BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo sapiens] (3177 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s... 6284 0.0 gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s... 5816 0.0 gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo ... 4815 0.0 gi|240255540 alpha 3 type VI collagen isoform 3 precursor [Homo ... 2293 0.0 gi|240255542 alpha 3 type VI collagen isoform 2 precursor [Homo ... 1910 0.0 gi|156616290 collagen type VI alpha 6 [Homo sapiens] 1144 0.0 gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens] 1032 0.0 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 336 2e-91 gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens] 335 4e-91 gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Hom... 325 4e-88 gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [H... 317 1e-85 gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Ho... 317 1e-85 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 307 9e-83 gi|154759255 collagen, type XXVIII precursor [Homo sapiens] 301 5e-81 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 298 7e-80 gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 296 2e-79 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 293 2e-78 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 293 2e-78 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 289 3e-77 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 289 3e-77 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 289 3e-77 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 286 2e-76 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 286 2e-76 gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 285 5e-76 gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 282 4e-75 gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 282 4e-75 gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 282 4e-75 gi|48762934 alpha 2 type I collagen [Homo sapiens] 280 2e-74 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 277 1e-73 gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] 274 9e-73 >gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo sapiens] Length = 3177 Score = 6284 bits (16304), Expect = 0.0 Identities = 3177/3177 (100%), Positives = 3177/3177 (100%) Query: 1 MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVRE 60 MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVRE Sbjct: 1 MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVRE 60 Query: 61 FLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGK 120 FLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGK Sbjct: 61 FLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGK 120 Query: 121 GLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDA 180 GLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDA Sbjct: 121 GLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDA 180 Query: 181 DEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDS 240 DEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDS Sbjct: 181 DEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDS 240 Query: 241 ADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYS 300 ADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYS Sbjct: 241 ADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYS 300 Query: 301 TKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSD 360 TKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSD Sbjct: 301 TKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSD 360 Query: 361 EIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIV 420 EIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIV Sbjct: 361 EIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIV 420 Query: 421 GVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQD 480 GVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQD Sbjct: 421 GVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQD 480 Query: 481 LIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSS 540 LIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSS Sbjct: 481 LIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSS 540 Query: 541 AGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSS 600 AGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSS Sbjct: 541 AGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSS 600 Query: 601 LVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRD 660 LVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRD Sbjct: 601 LVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRD 660 Query: 661 FVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTG 720 FVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTG Sbjct: 661 FVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTG 720 Query: 721 SALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQ 780 SALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQ Sbjct: 721 SALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQ 780 Query: 781 ANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILF 840 ANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILF Sbjct: 781 ANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILF 840 Query: 841 LFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEIL 900 LFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEIL Sbjct: 841 LFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEIL 900 Query: 901 NLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPA 960 NLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPA Sbjct: 901 NLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPA 960 Query: 961 SNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGA 1020 SNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGA Sbjct: 961 SNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGA 1020 Query: 1021 PAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEF 1080 PAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEF Sbjct: 1021 PAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEF 1080 Query: 1081 YLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLT 1140 YLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLT Sbjct: 1081 YLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLT 1140 Query: 1141 ADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQV 1200 ADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQV Sbjct: 1141 ADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQV 1200 Query: 1201 ISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVD 1260 ISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVD Sbjct: 1201 ISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVD 1260 Query: 1261 YLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVS 1320 YLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVS Sbjct: 1261 YLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVS 1320 Query: 1321 RNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVK 1380 RNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVK Sbjct: 1321 RNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVK 1380 Query: 1381 ISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFL 1440 ISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFL Sbjct: 1381 ISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFL 1440 Query: 1441 IDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVL 1500 IDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVL Sbjct: 1441 IDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVL 1500 Query: 1501 DAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFA 1560 DAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFA Sbjct: 1501 DAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFA 1560 Query: 1561 QVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATP 1620 QVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATP Sbjct: 1561 QVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATP 1620 Query: 1621 APPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGL 1680 APPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGL Sbjct: 1621 APPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGL 1680 Query: 1681 VQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLD 1740 VQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLD Sbjct: 1681 VQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLD 1740 Query: 1741 QRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVG 1800 QRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVG Sbjct: 1741 QRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVG 1800 Query: 1801 NVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFES 1860 NVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFES Sbjct: 1801 NVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFES 1860 Query: 1861 KVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQ 1920 KVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQ Sbjct: 1861 KVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQ 1920 Query: 1921 HPYVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILV 1980 HPYVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILV Sbjct: 1921 HPYVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILV 1980 Query: 1981 GLERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQR 2040 GLERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQR Sbjct: 1981 GLERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQR 2040 Query: 2041 GDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFP 2100 GDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFP Sbjct: 2041 GDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFP 2100 Query: 2101 GEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNP 2160 GEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNP Sbjct: 2101 GEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNP 2160 Query: 2161 GQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGF 2220 GQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGF Sbjct: 2161 GQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGF 2220 Query: 2221 EGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGP 2280 EGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGP Sbjct: 2221 EGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGP 2280 Query: 2281 KGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIR 2340 KGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIR Sbjct: 2281 KGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIR 2340 Query: 2341 GRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCPCCYGPLECPVFP 2400 GRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCPCCYGPLECPVFP Sbjct: 2341 GRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCPCCYGPLECPVFP 2400 Query: 2401 TELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRF 2460 TELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRF Sbjct: 2401 TELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRF 2460 Query: 2461 ADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPT 2520 ADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPT Sbjct: 2461 ADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPT 2520 Query: 2521 RASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLEN 2580 RASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLEN Sbjct: 2521 RASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLEN 2580 Query: 2581 VLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKK 2640 VLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKK Sbjct: 2581 VLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKK 2640 Query: 2641 YIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVD 2700 YIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVD Sbjct: 2641 YIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVD 2700 Query: 2701 FLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVIL 2760 FLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVIL Sbjct: 2701 FLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVIL 2760 Query: 2761 QAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKLVDKSTELNEEPLMRFGRLLPSFV 2820 QAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKLVDKSTELNEEPLMRFGRLLPSFV Sbjct: 2761 QAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKLVDKSTELNEEPLMRFGRLLPSFV 2820 Query: 2821 SSENAFYLSPDIRKQCDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTSNPVTTTKPVTTT 2880 SSENAFYLSPDIRKQCDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTSNPVTTTKPVTTT Sbjct: 2821 SSENAFYLSPDIRKQCDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTSNPVTTTKPVTTT 2880 Query: 2881 KPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPVAAKPVATKMATVRPPVAVKPAT 2940 KPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPVAAKPVATKMATVRPPVAVKPAT Sbjct: 2881 KPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPVAAKPVATKMATVRPPVAVKPAT 2940 Query: 2941 AAKPVAAKPAAVRPPAAAAAKPVATKPEVPRPQAAKPAATKPATTKPMVKMSREVQVFEI 3000 AAKPVAAKPAAVRPPAAAAAKPVATKPEVPRPQAAKPAATKPATTKPMVKMSREVQVFEI Sbjct: 2941 AAKPVAAKPAAVRPPAAAAAKPVATKPEVPRPQAAKPAATKPATTKPMVKMSREVQVFEI 3000 Query: 3001 TENSAKLHWERAEPPGPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGLLAGQTYHVAVVC 3060 TENSAKLHWERAEPPGPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGLLAGQTYHVAVVC Sbjct: 3001 TENSAKLHWERAEPPGPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGLLAGQTYHVAVVC 3060 Query: 3061 YLRSQVRATYHGSFSTKKSQPPPPQPARSASSSTINLMVSTEPLALTETDICKLPKDEGT 3120 YLRSQVRATYHGSFSTKKSQPPPPQPARSASSSTINLMVSTEPLALTETDICKLPKDEGT Sbjct: 3061 YLRSQVRATYHGSFSTKKSQPPPPQPARSASSSTINLMVSTEPLALTETDICKLPKDEGT 3120 Query: 3121 CRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAKPGVISVMGT 3177 CRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAKPGVISVMGT Sbjct: 3121 CRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAKPGVISVMGT 3177 >gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo sapiens] Length = 2971 Score = 5816 bits (15089), Expect = 0.0 Identities = 2942/2949 (99%), Positives = 2943/2949 (99%) Query: 229 TETLKDITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSD 288 T + AQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSD Sbjct: 23 THAQQQQAAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSD 82 Query: 289 EPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQ 348 EPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQ Sbjct: 83 EPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQ 142 Query: 349 VLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSF 408 VLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSF Sbjct: 143 VLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSF 202 Query: 409 GDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFI 468 GDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFI Sbjct: 203 GDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFI 262 Query: 469 AKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSA 528 AKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSA Sbjct: 263 AKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSA 322 Query: 529 LDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGAD 588 LDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGAD Sbjct: 323 LDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGAD 382 Query: 589 QAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSA 648 QAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSA Sbjct: 383 QAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSA 442 Query: 649 NVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQ 708 NVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQ Sbjct: 443 NVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQ 502 Query: 709 LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTR 768 LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTR Sbjct: 503 LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTR 562 Query: 769 AGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVP 828 AGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVP Sbjct: 563 AGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVP 622 Query: 829 LAQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVES 888 LAQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVES Sbjct: 623 LAQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVES 682 Query: 889 RFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLV 948 RFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLV Sbjct: 683 RFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLV 742 Query: 949 AGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQ 1008 AGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQ Sbjct: 743 AGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQ 802 Query: 1009 IVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVA 1068 IVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVA Sbjct: 803 IVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVA 862 Query: 1069 VVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRI 1128 VVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRI Sbjct: 863 VVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRI 922 Query: 1129 TEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAI 1188 TEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAI Sbjct: 923 TEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAI 982 Query: 1189 PTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEF 1248 PTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEF Sbjct: 983 PTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEF 1042 Query: 1249 QYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGR 1308 QYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGR Sbjct: 1043 QYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGR 1102 Query: 1309 QINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFT 1368 QINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFT Sbjct: 1103 QINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFT 1162 Query: 1369 IARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPP 1428 IARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPP Sbjct: 1163 IARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPP 1222 Query: 1429 AVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEF 1488 AVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEF Sbjct: 1223 AVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEF 1282 Query: 1489 YLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVL 1548 YLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVL Sbjct: 1283 YLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVL 1342 Query: 1549 GGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEER 1608 GGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEER Sbjct: 1343 GGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEER 1402 Query: 1609 IMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDT 1668 IMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDT Sbjct: 1403 IMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDT 1462 Query: 1669 VYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRV 1728 VYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRV Sbjct: 1463 VYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRV 1522 Query: 1729 NHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGK 1788 NHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGK Sbjct: 1523 NHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGK 1582 Query: 1789 IASNSATAFRVGNVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGSRD 1848 IASNSATAFRVGNVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGSRD Sbjct: 1583 IASNSATAFRVGNVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGSRD 1642 Query: 1849 QNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQP 1908 QNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQP Sbjct: 1643 QNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQP 1702 Query: 1909 EMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASEN 1968 EMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASEN Sbjct: 1703 EMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASEN 1762 Query: 1969 LRQEGVRALILVGLERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKA 2028 LRQEGVRALILVGLERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKA Sbjct: 1763 LRQEGVRALILVGLERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKA 1822 Query: 2029 CCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCP 2088 CCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCP Sbjct: 1823 CCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCP 1882 Query: 2089 GQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER 2148 GQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER Sbjct: 1883 GQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER 1942 Query: 2149 GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208 GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA Sbjct: 1943 GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2002 Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2268 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP Sbjct: 2003 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2062 Query: 2269 LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEP 2328 LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEP Sbjct: 2063 LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEP 2122 Query: 2329 GLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCP 2388 GLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCP Sbjct: 2123 GLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCP 2182 Query: 2389 CCYGPLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVV 2448 CCYGPLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVV Sbjct: 2183 CCYGPLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVV 2242 Query: 2449 TYNNEVTTEIRFADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLM 2508 TYNNEVTTEIRFADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLM Sbjct: 2243 TYNNEVTTEIRFADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLM 2302 Query: 2509 RKVAVFFSNTPTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVL 2568 RKVAVFFSNTPTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVL Sbjct: 2303 RKVAVFFSNTPTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVL 2362 Query: 2569 PAGRDLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAE 2628 PAGRDLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAE Sbjct: 2363 PAGRDLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAE 2422 Query: 2629 TTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFS 2688 TTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFS Sbjct: 2423 TTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFS 2482 Query: 2689 LTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVP 2748 LTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVP Sbjct: 2483 LTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVP 2542 Query: 2749 EQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKLVDKSTELNEEP 2808 EQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKLVDKSTELNEEP Sbjct: 2543 EQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKLVDKSTELNEEP 2602 Query: 2809 LMRFGRLLPSFVSSENAFYLSPDIRKQCDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTS 2868 LMRFGRLLPSFVSSENAFYLSPDIRKQCDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTS Sbjct: 2603 LMRFGRLLPSFVSSENAFYLSPDIRKQCDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTS 2662 Query: 2869 NPVTTTKPVTTTKPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPVAAKPVATKMA 2928 NPVTTTKPVTTTKPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPVAAKPVATKMA Sbjct: 2663 NPVTTTKPVTTTKPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPVAAKPVATKMA 2722 Query: 2929 TVRPPVAVKPATAAKPVAAKPAAVRPPAAAAAKPVATKPEVPRPQAAKPAATKPATTKPM 2988 TVRPPVAVKPATAAKPVAAKPAAVRPPAAAAAKPVATKPEVPRPQAAKPAATKPATTKPM Sbjct: 2723 TVRPPVAVKPATAAKPVAAKPAAVRPPAAAAAKPVATKPEVPRPQAAKPAATKPATTKPM 2782 Query: 2989 VKMSREVQVFEITENSAKLHWERAEPPGPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGL 3048 VKMSREVQVFEITENSAKLHWERAEPPGPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGL Sbjct: 2783 VKMSREVQVFEITENSAKLHWERAEPPGPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGL 2842 Query: 3049 LAGQTYHVAVVCYLRSQVRATYHGSFSTKKSQPPPPQPARSASSSTINLMVSTEPLALTE 3108 LAGQTYHVAVVCYLRSQVRATYHGSFSTKKSQPPPPQPARSASSSTINLMVSTEPLALTE Sbjct: 2843 LAGQTYHVAVVCYLRSQVRATYHGSFSTKKSQPPPPQPARSASSSTINLMVSTEPLALTE 2902 Query: 3109 TDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAK 3168 TDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAK Sbjct: 2903 TDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAK 2962 Query: 3169 PGVISVMGT 3177 PGVISVMGT Sbjct: 2963 PGVISVMGT 2971 Score = 1036 bits (2680), Expect = 0.0 Identities = 618/1672 (36%), Positives = 958/1672 (57%), Gaps = 57/1672 (3%) Query: 1 MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVRE 60 MRKHRHLPLVAVFCLFLSGFPTTHAQQQQA +ADIIFL+D S G +F ++ + Sbjct: 1 MRKHRHLPLVAVFCLFLSGFPTTHAQQQQAAQD---SADIIFLIDGSNNTGSVNFAVILD 57 Query: 61 FLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGG-TNQTG 119 FL ++++ L +G +VQF+ P T F L+TY TK +VL + + + GG G Sbjct: 58 FLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIG 117 Query: 120 KGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVED 179 L++++++H T+A GSR +GVPQV+V+++ G S D + LK A V F +G + Sbjct: 118 LALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQA 177 Query: 180 ADEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETL-KDITAQ 238 A L+ IA++ + +F + F S D+ L+ + T+ + Sbjct: 178 ASRAELQHIATD--DNLVFTVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEV 235 Query: 239 DSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDT 298 + DI+FL+DGS+ G NF I DF+ ++++L IG I+V V Q++D R F +T Sbjct: 236 NKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNT 295 Query: 299 YSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPS 358 + TK +V+ AV+ + G G ALDFV N FT + G R EG+P++LVLI+ G S Sbjct: 296 HPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKS 355 Query: 359 SDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPY 418 DEI LK++S+ +F +G + A +AEL+ IA D +LVF EFR+ LQ +LP Sbjct: 356 LDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRA-APLQ-GMLPG 413 Query: 419 IVGVAQRHIVLKPPTIVTQVIEV--NKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLE 476 + L P ++ EV NKRDI+FL+DGS+ +G NF +RDF+ ++ L+ Sbjct: 414 L---------LAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD 464 Query: 477 IGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNL 536 IG D I+V + Q++DT EF NT+ TK +++ +R+++ GS L TGSAL +V N Sbjct: 465 IGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANH 524 Query: 537 FTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIA 596 FT + G R E +P+LL+L+T G+S D Q A L R+ I+ F +G A++AELE+IA Sbjct: 525 FTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIA 584 Query: 597 FDSSLVFIPAEFRAAPLQGMLPGLLAPLRTL--SGTPEV----HSNKRDIIFLLDGSAN- 649 F+ SLV++ +F + P + L+ PL T G EV +KRDI+FL DGSAN Sbjct: 585 FNPSLVYLMDDFSSLP--ALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANL 642 Query: 650 VGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQL 709 VG+ FP VRDF+ +++ L++ + R+ + Q+SD E + +Q+K +IL ++++ Sbjct: 643 VGQ--FPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRM 700 Query: 710 QLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRA 769 +++ G LN G AL Y F ++ GSRI + V Q L+LL AG+S D A+ L ++ Sbjct: 701 KIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQS 760 Query: 770 GILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPL 829 G++ F A A+ AELEQI +P+ + + + L Q++ L + +G V Sbjct: 761 GVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPV-- 818 Query: 830 AQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESR 889 ++D++FL DGS + FP++++F+ ++++ L+V + R+AV QYSD + E Sbjct: 819 ---SGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFY 875 Query: 890 FDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVA 949 + + +K +++N V+++ + G N G AL++ R I V SAGSRI +GV Q L++L A Sbjct: 876 LNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTA 935 Query: 950 GRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQI 1009 RS D V P+ +K+ G VP NAD E++ I P F +A + ++G + I Sbjct: 936 DRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVI 995 Query: 1010 -----------VNLLKSVHNGAPAP-VSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVES 1057 ++ L+ V P+P V G++DVVFL+DGS+ F ++ ++R+V+ Sbjct: 996 SERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDY 1055 Query: 1058 LDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLR 1117 LDVG D RVAV+Q+SD + EF LN++ +K +V NAV++L GG N G ALE+V R Sbjct: 1056 LDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSR 1115 Query: 1118 NILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQT 1177 NI GSRI EGVPQ L+++++ +S D+V +P+V +K+ G P I NAD E+ Sbjct: 1116 NIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIA-RNADQEELVK 1174 Query: 1178 ISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFL 1237 IS P++ ++ TFR+L +++Q + +T LT E++ +L + P D+VFL Sbjct: 1175 ISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFL 1234 Query: 1238 IDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQ 1296 ID S+ P+ F ++R + R+V L++G RV V+QFS+D EF L + S+ V Sbjct: 1235 IDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVL 1294 Query: 1297 NAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPA 1356 +A++RLR +GG +N G ALE+V+RN+F + GSRIE+GVPQ LVL+ GKS D+V A Sbjct: 1295 DAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFA 1354 Query: 1357 VELKQFGVAPFTIA-RNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQ 1415 ++ G+ + RN D+ EL I+ P VF+V FRELP++E++++ + Sbjct: 1355 QVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATP 1414 Query: 1416 IQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRV 1475 + + PP E ADIVFL+D S R D F + FVS IV + ++V Sbjct: 1415 APPGVDTP--PPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQV 1472 Query: 1476 GVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSR 1535 G+VQ+++D EF+LK + ++ ++DAI ++ +GG NT LE + N FV AGSR Sbjct: 1473 GLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSR 1532 Query: 1536 IEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFT 1595 ++ VPQ ++ GGKS +D + + G+ VG RNID E+ I ++ F Sbjct: 1533 LDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFR 1592 Query: 1596 VREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGS 1647 V +EL + E+++ + + PGV + D++ DGS Sbjct: 1593 VGNVQELSELSEQVLETLHDAMHETLCPGV----TDAAKACNLDVILGFDGS 1640 Score = 672 bits (1733), Expect = 0.0 Identities = 419/1263 (33%), Positives = 680/1263 (53%), Gaps = 79/1263 (6%) Query: 17 LSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDF 76 LSG P H+ ++ DIIFL+D S +G+ +F VR+F+ ++V SL +G ++ Sbjct: 421 LSGTPEVHSNKR----------DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNI 470 Query: 77 HFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTN-QTGKGLEYIMQSHLTKAAG 135 LVQF+ P TEF LNTY+TK ++L H+ + GG+ TG L Y+ +H T+A G Sbjct: 471 RVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGG 530 Query: 136 SRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNM 195 SR + VPQ++++LT G S+D + L A + F +G A++ L++IA P + Sbjct: 531 SRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLV 590 Query: 196 HMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGS 255 ++ +++F+SL + L+ + + VS G E + + DI+FL DGS N Sbjct: 591 YL--MDDFSSLPALPQQLIQPLTTYVS----GGVEEVPLAQPESKRDILFLFDGSANLVG 644 Query: 256 VNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFA 315 F V+ DFL ++++L + + R+ V Q+SD+ + D + +K ++L VK + Sbjct: 645 -QFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIK 703 Query: 316 GGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVF 375 G+ N+G ALD+ F ++ GSR+E+GV Q LVL+ AG SSD + LKQ+ V Sbjct: 704 TGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVV 763 Query: 376 SFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIV 435 F A+ A AEL+ I + GDL +++ + V H P Sbjct: 764 PFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSV---HNGAPAPV-- 818 Query: 436 TQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRP 495 ++D+VFL+DGS + + F +++F+ +V++ L++GQD ++VAV QY+D RP Sbjct: 819 -----SGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRP 872 Query: 496 EFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVL 555 EFY N++ K++V+ AVR++ L G TG+AL+FV N+ SSAG R EG+P+LL++ Sbjct: 873 EFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIV 932 Query: 556 ITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAF-DSSLVFIPAEFRAAPLQ 614 +T +S D++ P+ +KR + IG AD E++ I+F V IP + +Q Sbjct: 933 LTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQ 992 Query: 615 GMLP-----------GLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVM 663 ++ L P+ +P V KRD++FL+DGS + G F YVR + Sbjct: 993 QVISERVTQLTREELSRLQPVLQPLPSPGV-GGKRDVVFLIDGSQSAG-PEFQYVRTLIE 1050 Query: 664 NLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSAL 723 LV+ LD+G D RV ++QFSD P EF LN + +K ++ +++L+ +GG +N G+AL Sbjct: 1051 RLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNAL 1110 Query: 724 SYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANK 783 YV N F GSRI E VPQ L+L+++G+S+D A L + G+ F + A A++ Sbjct: 1111 EYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI-ARNADQ 1169 Query: 784 AELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEV-------PLAQPESKR 836 EL +I+ +P V+ + F LP+L Q+L+ P+TT S ++++ P A Sbjct: 1170 EELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAA 1229 Query: 837 DILFLFDGSANL-VGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQS 895 DI+FL D S + F +RDF+ +I+ LN+ P R+ V Q+S+DV E ++S Sbjct: 1230 DIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRS 1289 Query: 896 KPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDR 955 + +L+ ++R++++ G LN G AL++ R +FVKSAGSRIEDGV Q LVL++ G+S D Sbjct: 1290 QAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDD 1349 Query: 956 VDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLL-K 1014 V A ++ SG+V +N D EL+ I P + ++ ++ +I+N Sbjct: 1350 VSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGP 1409 Query: 1015 SVHNGAP---------APVSGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDR 1064 S AP P + D+VFLLDGS R F + FV +V+++ D Sbjct: 1410 SAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDS 1469 Query: 1065 VRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSA 1124 ++V +VQY+ EF+L + K+ +++A+ ++ GG NT LE + N V A Sbjct: 1470 IQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEA 1529 Query: 1125 GSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDF 1184 GSR+ + VPQ+ V+T +S +D ++ S+ + + G +G+ N D E+ I Sbjct: 1530 GSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKI------ 1583 Query: 1185 AVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGV-----GGKRDVVFLID 1239 A T ++G VQ+ +++L+ + L L + PGV DV+ D Sbjct: 1584 ASNSATAFRVGNVQE-----LSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFD 1638 Query: 1240 GSQ 1242 GS+ Sbjct: 1639 GSR 1641 >gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo sapiens] Length = 2570 Score = 4815 bits (12490), Expect = 0.0 Identities = 2432/2562 (94%), Positives = 2475/2562 (96%), Gaps = 19/2562 (0%) Query: 627 LSGTPEVHS---------NKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIR 677 LSG P H+ NKRDI+FL+DGS+ +G NF +RDF+ ++ L+IG D I+ Sbjct: 17 LSGFPTTHAQQQQAVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQ 76 Query: 678 VGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGS 737 V + Q++DT EF NT+ TK +++ +R+++ GS L TGSAL +V N FT + G Sbjct: 77 VAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGY 136 Query: 738 RIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVY 797 R E +P+LL+L+T G+S D Q A L R+ I+ F +G A++AELE+IAF+ SLV+ Sbjct: 137 RAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVF 196 Query: 798 LMDDFSSLP--ALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANLVGQFPVV 855 + +F + P + L+ PL T +SG EE SKRDILFLFDGSANLVGQFPVV Sbjct: 197 IPAEFRAAPLQGMLPGLLAPLRT-LSGTPEE-------SKRDILFLFDGSANLVGQFPVV 248 Query: 856 RDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALN 915 RDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALN Sbjct: 249 RDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALN 308 Query: 916 LGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQA 975 LGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQA Sbjct: 309 LGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQA 368 Query: 976 KNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLD 1035 KNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLD Sbjct: 369 KNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLD 428 Query: 1036 GSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAV 1095 GSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAV Sbjct: 429 GSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAV 488 Query: 1096 RQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVV 1155 RQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVV Sbjct: 489 RQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVV 548 Query: 1156 KRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSR 1215 KRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSR Sbjct: 549 KRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSR 608 Query: 1216 LQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQ 1275 LQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQ Sbjct: 609 LQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQ 668 Query: 1276 FSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEG 1335 FSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEG Sbjct: 669 FSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEG 728 Query: 1336 VPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVKISLSPEYVFSVSTFR 1395 VPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVKISLSPEYVFSVSTFR Sbjct: 729 VPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVKISLSPEYVFSVSTFR 788 Query: 1396 ELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHI 1455 ELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHI Sbjct: 789 ELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHI 848 Query: 1456 RDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLN 1515 RDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLN Sbjct: 849 RDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLN 908 Query: 1516 TGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGD 1575 TGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGD Sbjct: 909 TGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGD 968 Query: 1576 RNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEK 1635 RNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEK Sbjct: 969 RNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEK 1028 Query: 1636 KKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKD 1695 KKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKD Sbjct: 1029 KKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKD 1088 Query: 1696 FSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKS 1755 FSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKS Sbjct: 1089 FSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKS 1148 Query: 1756 VEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLET 1815 VEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLET Sbjct: 1149 VEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLET 1208 Query: 1816 LHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFESKVDAILNRISQMHRV 1875 LHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFESKVDAILNRISQMHRV Sbjct: 1209 LHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFESKVDAILNRISQMHRV 1268 Query: 1876 SCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQHPYVLTEDTLKVYLN 1935 SCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQHPYVLTEDTLKVYLN Sbjct: 1269 SCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQHPYVLTEDTLKVYLN 1328 Query: 1936 KFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILVGLERVVNLERLMHLE 1995 KFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILVGLERVVNLERLMHLE Sbjct: 1329 KFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILVGLERVVNLERLMHLE 1388 Query: 1996 FGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQRGDRGPIGSIGPKGIP 2055 FGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQRGDRGPIGSIGPKGIP Sbjct: 1389 FGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQRGDRGPIGSIGPKGIP 1448 Query: 2056 GEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLD 2115 GEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLD Sbjct: 1449 GEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLD 1508 Query: 2116 GEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGD 2175 GEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGD Sbjct: 1509 GEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGD 1568 Query: 2176 LGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGP 2235 LGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGP Sbjct: 1569 LGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGP 1628 Query: 2236 AGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGD 2295 AGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGD Sbjct: 1629 AGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGD 1688 Query: 2296 DGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355 DGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK Sbjct: 1689 DGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 1748 Query: 2356 GDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVNQ 2415 GDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVNQ Sbjct: 1749 GDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVNQ 1808 Query: 2416 DTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFADSKRKSVLLDKIKN 2475 DTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFADSKRKSVLLDKIKN Sbjct: 1809 DTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFADSKRKSVLLDKIKN 1868 Query: 2476 LQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTRASPQLREAVLKLSD 2535 LQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTRASPQLREAVLKLSD Sbjct: 1869 LQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTRASPQLREAVLKLSD 1928 Query: 2536 AGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLENVLTCHVCLDICNIDP 2595 AGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLENVLTCHVCLDICNIDP Sbjct: 1929 AGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLENVLTCHVCLDICNIDP 1988 Query: 2596 SCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDP 2655 SCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDP Sbjct: 1989 SCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDP 2048 Query: 2656 KASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRAL 2715 KASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRAL Sbjct: 2049 KASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRAL 2108 Query: 2716 GSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIG 2775 GSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIG Sbjct: 2109 GSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIG 2168 Query: 2776 RKVNIKEVYTFASEPNDVFFKLVDKSTELNEEPLMRFGRLLPSFVSSENAFYLSPDIRKQ 2835 RKVNIKEVYTFASEPNDVFFKLVDKSTELNEEPLMRFGRLLPSFVSSENAFYLSPDIRKQ Sbjct: 2169 RKVNIKEVYTFASEPNDVFFKLVDKSTELNEEPLMRFGRLLPSFVSSENAFYLSPDIRKQ 2228 Query: 2836 CDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTSNPVTTTKPVTTTKPVTTTTKPVTTTTK 2895 CDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTSNPVTTTKPVTTTKPVTTTTKPVTTTTK Sbjct: 2229 CDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTSNPVTTTKPVTTTKPVTTTTKPVTTTTK 2288 Query: 2896 PVTIINQPSVKPAAAKPAPAKPVAAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPP 2955 PVTIINQPSVKPAAAKPAPAKPVAAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPP Sbjct: 2289 PVTIINQPSVKPAAAKPAPAKPVAAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPP 2348 Query: 2956 AAAAAKPVATKPEVPRPQAAKPAATKPATTKPMVKMSREVQVFEITENSAKLHWERAEPP 3015 AAAAAKPVATKPEVPRPQAAKPAATKPATTKPMVKMSREVQVFEITENSAKLHWERAEPP Sbjct: 2349 AAAAAKPVATKPEVPRPQAAKPAATKPATTKPMVKMSREVQVFEITENSAKLHWERAEPP 2408 Query: 3016 GPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGLLAGQTYHVAVVCYLRSQVRATYHGSFS 3075 GPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGLLAGQTYHVAVVCYLRSQVRATYHGSFS Sbjct: 2409 GPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGLLAGQTYHVAVVCYLRSQVRATYHGSFS 2468 Query: 3076 TKKSQPPPPQPARSASSSTINLMVSTEPLALTETDICKLPKDEGTCRDFILKWYYDPNTK 3135 TKKSQPPPPQPARSASSSTINLMVSTEPLALTETDICKLPKDEGTCRDFILKWYYDPNTK Sbjct: 2469 TKKSQPPPPQPARSASSSTINLMVSTEPLALTETDICKLPKDEGTCRDFILKWYYDPNTK 2528 Query: 3136 SCARFWYGGCGGNENKFGSQKECEKVCAPVLAKPGVISVMGT 3177 SCARFWYGGCGGNENKFGSQKECEKVCAPVLAKPGVISVMGT Sbjct: 2529 SCARFWYGGCGGNENKFGSQKECEKVCAPVLAKPGVISVMGT 2570 Score = 988 bits (2553), Expect = 0.0 Identities = 560/1225 (45%), Positives = 778/1225 (63%), Gaps = 31/1225 (2%) Query: 438 VIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEF 497 VIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEF Sbjct: 31 VIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEF 90 Query: 498 YFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLIT 557 YFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLIT Sbjct: 91 YFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLIT 150 Query: 558 GGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGML 617 GGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGML Sbjct: 151 GGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGML 210 Query: 618 PGLLAPLRTLSGTPEVHSNKRDIIFLLDGSAN-VGKTNFPYVRDFVMNLVNSLDIGNDNI 676 PGLLAPLRTLSGTPE +KRDI+FL DGSAN VG+ FP VRDF+ +++ L++ + Sbjct: 211 PGLLAPLRTLSGTPE--ESKRDILFLFDGSANLVGQ--FPVVRDFLYKIIDELNVKPEGT 266 Query: 677 RVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGG 736 R+ + Q+SD E + +Q+K +IL +++++++ G LN G AL Y F ++ G Sbjct: 267 RIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAG 326 Query: 737 SRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLV 796 SRI + V Q L+LL AG+S D A+ L ++G++ F A A+ AELEQI +P+ + Sbjct: 327 SRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFI 386 Query: 797 YLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANLVGQFPVVR 856 + + L Q++ L + +G V ++D++FL DGS + FP+++ Sbjct: 387 LAAESLPKIGDLHPQIVNLLKSVHNGAPAPV-----SGEKDVVFLLDGSEGVRSGFPLLK 441 Query: 857 DFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNL 916 +F+ ++++ L+V + R+AV QYSD + E + + +K +++N V+++ + G N Sbjct: 442 EFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNT 501 Query: 917 GYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAK 976 G AL++ R I V SAGSRI +GV Q L++L A RS D V P+ +K+ G VP Sbjct: 502 GAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIG 561 Query: 977 NADPAELEQIVLSPAFILAAESLPKIGDLHPQI-----------VNLLKSVHNGAPAP-V 1024 NAD E++ I P F +A + ++G + I ++ L+ V P+P V Sbjct: 562 NADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGV 621 Query: 1025 SGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNS 1084 G++DVVFL+DGS+ F ++ ++R+V+ LDVG D RVAV+Q+SD + EF LN+ Sbjct: 622 GGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 681 Query: 1085 YMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRS 1144 + +K +V NAV++L GG N G ALE+V RNI GSRI EGVPQ L+++++ +S Sbjct: 682 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKS 741 Query: 1145 GDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISER 1204 D+V +P+V +K+ G P I NAD E+ IS P++ ++ TFR+L +++Q + Sbjct: 742 DDEVDDPAVELKQFGVAPFTIA-RNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTP 800 Query: 1205 VTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLD 1263 +T LT E++ +L + P D+VFLID S+ P+ F ++R + R+V L+ Sbjct: 801 ITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLN 860 Query: 1264 VGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNI 1323 +G RV V+QFS+D EF L + S+ V +A++RLR +GG +N G ALE+V+RN+ Sbjct: 861 IGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNL 920 Query: 1324 FKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIA-RNADQEELVKIS 1382 F + GSRIE+GVPQ LVL+ GKS D+V A ++ G+ + RN D+ EL I+ Sbjct: 921 FVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTIT 980 Query: 1383 LSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLID 1442 P VF+V FRELP++E++++ + + + PP E ADIVFL+D Sbjct: 981 NDPRLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDTP--PPSRPEKKKADIVFLLD 1038 Query: 1443 SSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDA 1502 S R D F + FVS IV + ++VG+VQ+++D EF+LK + ++ ++DA Sbjct: 1039 GSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDA 1098 Query: 1503 IRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQV 1562 I ++ +GG NT LE + N FV AGSR++ VPQ ++ GGKS +D + Sbjct: 1099 INKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLA 1158 Query: 1563 IRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAP 1622 + G+ VG RNID E+ I ++ F V +EL + E+++ + + Sbjct: 1159 LTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLETLHDAMHETLC 1218 Query: 1623 PGVDTPPPSRPEKKKADIVFLLDGS 1647 PGV + D++ DGS Sbjct: 1219 PGV----TDAAKACNLDVILGFDGS 1239 Score = 763 bits (1970), Expect = 0.0 Identities = 462/1189 (38%), Positives = 686/1189 (57%), Gaps = 45/1189 (3%) Query: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 301 DI+FL+DGS+ G NF I DF+ ++++L IG I+V V Q++D R F +T+ T Sbjct: 38 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 97 Query: 302 KAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDE 361 K +V+ AV+ + G G ALDFV N FT + G R EG+P++LVLI+ G S DE Sbjct: 98 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDE 157 Query: 362 IRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIVG 421 I LK++S+ +F +G + A +AEL+ IA D +LVF EFR+ LQ +LP + Sbjct: 158 ISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRA-APLQ-GMLPGL-- 213 Query: 422 VAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDL 481 L P ++ E +KRDI+FL DGS+ L + F +RDF+ K+I L + + Sbjct: 214 -------LAPLRTLSGTPEESKRDILFLFDGSANL-VGQFPVVRDFLYKIIDELNVKPEG 265 Query: 482 IQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSA 541 ++AVAQY+D V+ E F+ H +K E++ V++MK G AL G ALD+ + +F SA Sbjct: 266 TRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSA 325 Query: 542 GYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSL 601 G R +G+ + LVL+ G+S D + PA LK+S ++ F K AD AELE+I S Sbjct: 326 GSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVL--SP 383 Query: 602 VFIPAEFRAAPLQGMLPGLLAPLRTL-SGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRD 660 FI A + + P ++ L+++ +G P S ++D++FLLDGS V ++ FP +++ Sbjct: 384 AFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGV-RSGFPLLKE 442 Query: 661 FVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTG 720 FV +V SLD+G D +RV +VQ+SD EF LN+Y K D++ +RQL L GG NTG Sbjct: 443 FVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTG 502 Query: 721 SALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQ 780 +AL +V N + GSRI E VPQLL++LTA +S D + + R G + +G Sbjct: 503 AALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGN 562 Query: 781 ANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEV-PLAQP------E 833 A+ E++ I+F P + F L + Q + + +T + + P+ QP Sbjct: 563 ADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVG 622 Query: 834 SKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEH 893 KRD++FL DGS + +F VR + +++D L+V + TR+AV Q+SDD KVE + H Sbjct: 623 GKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAH 682 Query: 894 QSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSS 953 SK E+ N V+R++ K G+ +N+G AL+Y R IF + GSRIE+GV QFLVL+ +G+S Sbjct: 683 SSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSD 742 Query: 954 DRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLH------- 1006 D VD PA LKQ GV PF A+NAD EL +I LSP ++ + + ++ L Sbjct: 743 DEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPI 801 Query: 1007 -----PQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVR-SGFPLLKEFVQRVVESLDV 1060 QI LL S PA S D+VFL+D SEGVR GF +++FV R+V L++ Sbjct: 802 TTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNI 861 Query: 1061 GQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNIL 1120 G +VRV VVQ+S+ PEFYL +Y ++ V++A+R+L L GG NTG ALEFV RN+ Sbjct: 862 GPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLF 921 Query: 1121 VSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISF 1180 V SAGSRI +GVPQ L+++ +S DDV + V++ G V +G+G N D TE+QTI+ Sbjct: 922 VKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITN 981 Query: 1181 IPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQP--VLQPLPSPGVGGKRDVVFLI 1238 P + FR+L ++ ER+ + P V P PS K D+VFL+ Sbjct: 982 DPRLVFTVREFRELPNIE----ERIMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLL 1037 Query: 1239 DGS-QSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQN 1297 DGS FQ V + +VD + D+ +V ++Q++ DP EF L S+K ++ + Sbjct: 1038 DGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIID 1097 Query: 1298 AVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAV 1357 A+ ++ KGGR N LE++ N F GSR+++ VPQ +I+ GKS ++ D ++ Sbjct: 1098 AINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSL 1157 Query: 1358 ELKQFGVAPFTI-ARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLL 1405 L Q GV F + RN D EE+ KI+ + F V +EL L +++L Sbjct: 1158 ALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVL 1206 Score = 705 bits (1820), Expect = 0.0 Identities = 436/1279 (34%), Positives = 694/1279 (54%), Gaps = 76/1279 (5%) Query: 1 MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVRE 60 MRKHRHLPLVAVFCLFLSGFPTTHAQQQQA ++ DI+FLVD S +G +F +R+ Sbjct: 1 MRKHRHLPLVAVFCLFLSGFPTTHAQQQQAVIEVN-KRDIVFLVDGSSALGLANFNAIRD 59 Query: 61 FLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTN-QTG 119 F+ V++ L +G++ A+ Q+ EF NT+ TK+EV++ + M + G+ TG Sbjct: 60 FIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTG 119 Query: 120 KGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVED 179 L+++ + T +AG RA +G+P+++V++T G S D ++ P+ ELK + + FAIG + Sbjct: 120 SALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKG 179 Query: 180 ADEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQD 239 AD+ L+EIA + +SL I + + P TL + Sbjct: 180 ADQAELEEIAFD------------SSLVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEES 227 Query: 240 SADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTY 299 DI+FL DGS N F V+ DFL ++++L + + R+ V Q+SD+ + D + Sbjct: 228 KRDILFLFDGSANLVG-QFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEH 286 Query: 300 STKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSS 359 +K ++L VK + G+ N+G ALD+ F ++ GSR+E+GV Q LVL+ AG SS Sbjct: 287 QSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSS 346 Query: 360 DEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYI 419 D + LKQ+ V F A+ A AEL+ I + GDL +++ + Sbjct: 347 DRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLL 406 Query: 420 VGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQ 479 V H P ++D+VFL+DGS + + F +++F+ +V++ L++GQ Sbjct: 407 KSV---HNGAPAPV-------SGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQ 455 Query: 480 DLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTS 539 D ++VAV QY+D RPEFY N++ K++V+ AVR++ L G TG+AL+FV N+ S Sbjct: 456 DRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVS 515 Query: 540 SAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAF-D 598 SAG R EG+P+LL+++T +S D++ P+ +KR + IG AD E++ I+F Sbjct: 516 SAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIP 575 Query: 599 SSLVFIPAEFRAAPLQGMLP-----------GLLAPLRTLSGTPEVHSNKRDIIFLLDGS 647 V IP + +Q ++ L P+ +P V KRD++FL+DGS Sbjct: 576 DFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGV-GGKRDVVFLIDGS 634 Query: 648 ANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLR 707 + G F YVR + LV+ LD+G D RV ++QFSD P EF LN + +K ++ ++ Sbjct: 635 QSAG-PEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQ 693 Query: 708 QLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALT 767 +L+ +GG +N G+AL YV N F GSRI E VPQ L+L+++G+S+D A L Sbjct: 694 RLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELK 753 Query: 768 RAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEV 827 + G+ F + A A++ EL +I+ +P V+ + F LP+L Q+L+ P+TT S ++++ Sbjct: 754 QFGVAPFTI-ARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKL 812 Query: 828 -------PLAQPESKRDILFLFDGSANL-VGQFPVVRDFLYKIIDELNVKPEGTRIAVAQ 879 P A DI+FL D S + F +RDF+ +I+ LN+ P R+ V Q Sbjct: 813 LASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQ 872 Query: 880 YSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDG 939 +S+DV E ++S+ +L+ ++R++++ G LN G AL++ R +FVKSAGSRIEDG Sbjct: 873 FSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDG 932 Query: 940 VLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESL 999 V Q LVL++ G+S D V A ++ SG+V +N D EL+ I P + Sbjct: 933 VPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREF 992 Query: 1000 PKIGDLHPQIVNLL-KSVHNGAP---------APVSGEKDVVFLLDGSEGV-RSGFPLLK 1048 ++ ++ +I+N S AP P + D+VFLLDGS R F + Sbjct: 993 RELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVL 1052 Query: 1049 EFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNT 1108 FV +V+++ D ++V +VQY+ EF+L + K+ +++A+ ++ GG NT Sbjct: 1053 RFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANT 1112 Query: 1109 GAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIG 1168 LE + N V AGSR+ + VPQ+ V+T +S +D ++ S+ + + G +G+ Sbjct: 1113 KVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVR 1172 Query: 1169 NADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGV 1228 N D E+ I A T ++G VQ+ +++L+ + L L + PGV Sbjct: 1173 NIDSEEVGKI------ASNSATAFRVGNVQE-----LSELSEQVLETLHDAMHETLCPGV 1221 Query: 1229 -----GGKRDVVFLIDGSQ 1242 DV+ DGS+ Sbjct: 1222 TDAAKACNLDVILGFDGSR 1240 Score = 315 bits (807), Expect = 5e-85 Identities = 226/735 (30%), Positives = 363/735 (49%), Gaps = 46/735 (6%) Query: 35 GAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLN 94 G D++FL+D S + G E FQ VR + +V L VG + A++QF+ +P EFLLN Sbjct: 622 GGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLN 680 Query: 95 TYRTKQEVLSHISNMSYIGGTN-QTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGH 153 + +K EV + + + GG G LEY+ ++ + GSR +GVPQ +V+++ G Sbjct: 681 AHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGK 740 Query: 154 SKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDIVGNL 213 S D + P+ ELK V F I +AD+ L +I+ P ++F++ F L + L Sbjct: 741 SDDEVDDPAVELKQFGVAPFTIA-RNADQEELVKISLSP--EYVFSVSTFRELPSLEQKL 797 Query: 214 VSCVHSSVSPE---RAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLE 270 ++ + + S + T D+ADI+FLID S FA I DF+ ++ Sbjct: 798 LTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVR 857 Query: 271 KLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVV 330 +L IG ++RVGVVQFS++ F L TY ++A VL A++ L GG N G AL+FV Sbjct: 858 RLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVA 917 Query: 331 ENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQ 390 N F ++ GSR+E+GVPQ LVL+ G S D++ ++ + + S G+G + R ELQ Sbjct: 918 RNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQ 977 Query: 391 HIATDDNLVFTVPEFRSFGDLQEKLL----PYIVGVAQRHIVLKPPTIVTQVIEVNKRDI 446 I D LVFTV EFR +++E+++ P A + PP+ E K DI Sbjct: 978 TITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRP----EKKKADI 1033 Query: 447 VFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKR 506 VFL+DGS +F + F+++++ + D IQV + QY EF+ TKR Sbjct: 1034 VFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKR 1093 Query: 507 EVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEIS 566 ++I A+ K+ G T L+ +R N F AG R + +P++ +ITGGKS+++ Sbjct: 1094 QIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQ 1153 Query: 567 QPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRT 626 + L + + FA+G + D E+ +IA +S+ FR +Q + L T Sbjct: 1154 DVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSA-----TAFRVGNVQELSELSEQVLET 1208 Query: 627 LSG----------TPEVHSNKRDIIFLLDGSAN----VGKTNFPYVRDFVMNLVNSLDI- 671 L T + D+I DGS + V + F D ++N ++ + Sbjct: 1209 LHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFESKVDAILNRISQMHRV 1268 Query: 672 -----GNDNIRVGLVQFSDT-PVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSY 725 + +RV +V + + PV F + YQ ++L R ++ Q L + Sbjct: 1269 SCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQ--PEMLEKFRNMRSQHPYVLTEDTL--K 1324 Query: 726 VYANHFTEAGGSRIR 740 VY N F ++ ++ Sbjct: 1325 VYLNKFRQSSPDSVK 1339 Score = 58.9 bits (141), Expect = 8e-08 Identities = 81/370 (21%), Positives = 155/370 (41%), Gaps = 52/370 (14%) Query: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQI----RVGVVQFSDEPRTMFSLD 297 ++ F +D S F + D +++++ L I RV VV +++E T Sbjct: 1795 ELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 1854 Query: 298 TYSTKAQVLGAVKALGFA-GGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAG 356 K+ +L +K L A + ++ A+ FV N F R + + +V V S Sbjct: 1855 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFL---MRKVAVFFSNT 1911 Query: 357 PS--SDEIRYGVVALKQASVFSFGL----GAQAASRAELQHIATDDNLVFTVPEFRSFGD 410 P+ S ++R V+ L A + L Q + ++ + A LV +P R D Sbjct: 1912 PTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALV--LPAGRDLTD 1969 Query: 411 LQEKLLPYIV-----------GVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLA 459 E +L V G + +++ D+ F++D + L Sbjct: 1970 FLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDI---DMAFILDSAETTTLF 2026 Query: 460 NFNAIRDFIAKVIQRLEIGQD------LIQVAVAQYADT----------VRPEFYFNTHP 503 FN ++ +IA ++++L++ D +VAV Q+A + V+ EF + Sbjct: 2027 QFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYG 2086 Query: 504 TKREVITAV-RKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSL 562 +K +++ + R M L G+ GSA+++ N+F S+ R K++VL+ G+ Sbjct: 2087 SKEKLVDFLSRGMTQLQGTRA-LGSAIEYTIENVFESAPNPRDL----KIVVLMLTGEVP 2141 Query: 563 DEISQPAQEL 572 ++ + AQ + Sbjct: 2142 EQQLEEAQRV 2151 >gi|240255540 alpha 3 type VI collagen isoform 3 precursor [Homo sapiens] Length = 1237 Score = 2293 bits (5942), Expect = 0.0 Identities = 1195/1210 (98%), Positives = 1200/1210 (99%), Gaps = 1/1210 (0%) Query: 229 TETLKDITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSD 288 T + AQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSD Sbjct: 23 THAQQQQAAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSD 82 Query: 289 EPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQ 348 EPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQ Sbjct: 83 EPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQ 142 Query: 349 VLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSF 408 VLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSF Sbjct: 143 VLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSF 202 Query: 409 GDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFI 468 GDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFI Sbjct: 203 GDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFI 262 Query: 469 AKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSA 528 AKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSA Sbjct: 263 AKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSA 322 Query: 529 LDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGAD 588 LDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGAD Sbjct: 323 LDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGAD 382 Query: 589 QAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSA 648 QAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSA Sbjct: 383 QAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSA 442 Query: 649 NVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQ 708 NVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQ Sbjct: 443 NVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQ 502 Query: 709 LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTR 768 LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTR Sbjct: 503 LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTR 562 Query: 769 AGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVP 828 AGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVP Sbjct: 563 AGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVP 622 Query: 829 LAQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVES 888 LAQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVES Sbjct: 623 LAQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVES 682 Query: 889 RFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLV 948 RFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLV Sbjct: 683 RFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLV 742 Query: 949 AGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQ 1008 AGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQ Sbjct: 743 AGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQ 802 Query: 1009 IVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVA 1068 IVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVA Sbjct: 803 IVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVA 862 Query: 1069 VVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRI 1128 VVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRI Sbjct: 863 VVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRI 922 Query: 1129 TEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAI 1188 TEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAI Sbjct: 923 TEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAI 982 Query: 1189 PTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEF 1248 PTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEF Sbjct: 983 PTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEF 1042 Query: 1249 QYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGR 1308 QYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGR Sbjct: 1043 QYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGR 1102 Query: 1309 QINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFT 1368 QINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFT Sbjct: 1103 QINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFT 1162 Query: 1369 IARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPP 1428 IARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPP Sbjct: 1163 IARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPP 1222 Query: 1429 AVESDAADIV 1438 E A++++ Sbjct: 1223 G-EMGASEVL 1231 Score = 797 bits (2059), Expect = 0.0 Identities = 476/1212 (39%), Positives = 703/1212 (58%), Gaps = 54/1212 (4%) Query: 627 LSGTPEVHSNKR-------DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVG 679 LSG P H+ ++ DIIFL+DGS N G NF + DF++NL+ L IG IRVG Sbjct: 17 LSGFPTTHAQQQQAAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVG 76 Query: 680 LVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRI 739 +VQFSD P T FSL+TY TK+ +LG ++ L GG N G AL +V NHFT AGGSR+ Sbjct: 77 VVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRV 136 Query: 740 REHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLM 799 E VPQ+L+L++AG S D AL +A + +F +GA A++AEL+ IA + +LV+ + Sbjct: 137 EEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTV 196 Query: 800 DDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPES---------KRDILFLFDGSANL-V 849 +F S L ++L+ Y+ G + + +P + KRDI+FL DGS+ L + Sbjct: 197 PEFRSFGDLQEKLLP----YIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGL 252 Query: 850 GQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIK 909 F +RDF+ K+I L + + ++AVAQY+D V+ E F+ H +K E++ V++MK Sbjct: 253 ANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPL 312 Query: 910 TGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVV 969 G AL G ALD+ + +F SAG R +G+ + LVL+ G+S D + PA LK+S ++ Sbjct: 313 DGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIM 372 Query: 970 PFIFQAKNADPAELEQIVL--SPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGE 1027 F K AD AELE+I S FI A + + P ++ L+++ +G P S + Sbjct: 373 AFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTL-SGTPEVHSNK 431 Query: 1028 KDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYM 1086 +D++FLLDGS V ++ FP +++FV +V SLD+G D +RV +VQ+SD EF LN+Y Sbjct: 432 RDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQ 491 Query: 1087 NKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGD 1146 K D++ +RQL L GG NTG+AL +V N + GSRI E VPQLL++LTA +S D Sbjct: 492 TKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSED 551 Query: 1147 DVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVT 1206 + + R G + +G A+ E++ I+F P + F L + Q + + +T Sbjct: 552 SYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLT 611 Query: 1207 QLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGF 1266 + + P+ QP KRD++FL DGS + +F VR + +++D L+V Sbjct: 612 TYVSGGVEEV-PLAQP------ESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKP 664 Query: 1267 DTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKR 1326 + TR+AV Q+SDD KVE + H SK E+ N V+R++ K G+ +N+G AL+Y R IF + Sbjct: 665 EGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVK 724 Query: 1327 PLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP 1385 GSRIE+GV QFLVL+ +G+S D VD PA LKQ GV PF A+NAD EL +I LSP Sbjct: 725 SAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSP 784 Query: 1386 EYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSE 1445 ++ + + ++ L QI LL S PA S D+VFL+D SE Sbjct: 785 AFILAAESLPKIGDLHP------------QIVNLLKSVHNGAPAPVSGEKDVVFLLDGSE 832 Query: 1446 GVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRR 1505 GVR GF +++FV R+V L++G +VRV VVQ+S+ PEFYL +Y ++ V++A+R+ Sbjct: 833 GVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQ 891 Query: 1506 LRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRS 1565 L L GG NTG ALEFV RN+ V SAGSRI +GVPQ L+++ +S DDV + V++ Sbjct: 892 LTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKR 951 Query: 1566 SGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIE----ERIMNSFGPSAATPA 1621 G V +G+G N D TE+QTI+ P + FR+L ++ ER+ + Sbjct: 952 GGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQ 1011 Query: 1622 PPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLV 1681 P V P PS K D+VFL+DGS FQ V + +VD + D+ +V ++ Sbjct: 1012 P--VLQPLPSPGVGGKRDVVFLIDGS-QSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVI 1068 Query: 1682 QYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQ 1741 Q++ DP EF L S+K ++ +A+ ++ KGGR N LE++ N F GSR+++ Sbjct: 1069 QFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE 1128 Query: 1742 RVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGN 1801 VPQ +I+ GKS ++ D ++ L Q GV F + RN D EE+ KI+ + F V Sbjct: 1129 GVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSPEYVFSVST 1187 Query: 1802 VQELSELSEQVL 1813 +EL L +++L Sbjct: 1188 FRELPSLEQKLL 1199 Score = 794 bits (2050), Expect = 0.0 Identities = 473/1258 (37%), Positives = 734/1258 (58%), Gaps = 50/1258 (3%) Query: 1 MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVRE 60 MRKHRHLPLVAVFCLFLSGFPTTHAQQQQA +ADIIFL+D S G +F ++ + Sbjct: 1 MRKHRHLPLVAVFCLFLSGFPTTHAQQQQAAQD---SADIIFLIDGSNNTGSVNFAVILD 57 Query: 61 FLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGG-TNQTG 119 FL ++++ L +G +VQF+ P T F L+TY TK +VL + + + GG G Sbjct: 58 FLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIG 117 Query: 120 KGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVED 179 L++++++H T+A GSR +GVPQV+V+++ G S D + LK A V F +G + Sbjct: 118 LALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQA 177 Query: 180 ADEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETL-KDITAQ 238 A L+ IA++ + +F + F S D+ L+ + T+ + Sbjct: 178 ASRAELQHIATD--DNLVFTVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEV 235 Query: 239 DSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDT 298 + DI+FL+DGS+ G NF I DF+ ++++L IG I+V V Q++D R F +T Sbjct: 236 NKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNT 295 Query: 299 YSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPS 358 + TK +V+ AV+ + G G ALDFV N FT + G R EG+P++LVLI+ G S Sbjct: 296 HPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKS 355 Query: 359 SDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPY 418 DEI LK++S+ +F +G + A +AEL+ IA D +LVF EFR+ LQ +LP Sbjct: 356 LDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRA-APLQ-GMLPG 413 Query: 419 IVGVAQRHIVLKPPTIVTQVIEV--NKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLE 476 + L P ++ EV NKRDI+FL+DGS+ +G NF +RDF+ ++ L+ Sbjct: 414 L---------LAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD 464 Query: 477 IGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNL 536 IG D I+V + Q++DT EF NT+ TK +++ +R+++ GS L TGSAL +V N Sbjct: 465 IGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANH 524 Query: 537 FTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIA 596 FT + G R E +P+LL+L+T G+S D Q A L R+ I+ F +G A++AELE+IA Sbjct: 525 FTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIA 584 Query: 597 FDSSLVFIPAEFRAAPLQGMLPGLLAPLRTL--SGTPEV----HSNKRDIIFLLDGSAN- 649 F+ SLV++ +F + P + L+ PL T G EV +KRDI+FL DGSAN Sbjct: 585 FNPSLVYLMDDFSSLP--ALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANL 642 Query: 650 VGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQL 709 VG+ FP VRDF+ +++ L++ + R+ + Q+SD E + +Q+K +IL ++++ Sbjct: 643 VGQ--FPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRM 700 Query: 710 QLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRA 769 +++ G LN G AL Y F ++ GSRI + V Q L+LL AG+S D A+ L ++ Sbjct: 701 KIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQS 760 Query: 770 GILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPL 829 G++ F A A+ AELEQI +P+ + + + L Q++ L + +G V Sbjct: 761 GVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPV-- 818 Query: 830 AQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESR 889 ++D++FL DGS + FP++++F+ ++++ L+V + R+AV QYSD + E Sbjct: 819 ---SGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFY 875 Query: 890 FDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVA 949 + + +K +++N V+++ + G N G AL++ R I V SAGSRI +GV Q L++L A Sbjct: 876 LNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTA 935 Query: 950 GRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQI 1009 RS D V P+ +K+ G VP NAD E++ I P F +A + ++G + I Sbjct: 936 DRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVI 995 Query: 1010 -----------VNLLKSVHNGAPAP-VSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVES 1057 ++ L+ V P+P V G++DVVFL+DGS+ F ++ ++R+V+ Sbjct: 996 SERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDY 1055 Query: 1058 LDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLR 1117 LDVG D RVAV+Q+SD + EF LN++ +K +V NAV++L GG N G ALE+V R Sbjct: 1056 LDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSR 1115 Query: 1118 NILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQT 1177 NI GSRI EGVPQ L+++++ +S D+V +P+V +K+ G P I NAD E+ Sbjct: 1116 NIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIA-RNADQEELVK 1174 Query: 1178 ISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVV 1235 IS P++ ++ TFR+L +++Q + +T LT E++ +L + P PG G +V+ Sbjct: 1175 ISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTR-YPPPGEMGASEVL 1231 Score = 550 bits (1418), Expect = e-156 Identities = 345/1041 (33%), Positives = 558/1041 (53%), Gaps = 62/1041 (5%) Query: 833 ESKRDILFLFDGSANLVG-QFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFD 891 + DI+FL DGS N F V+ DFL ++++L + + R+ V Q+SD+ + D Sbjct: 32 QDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLD 91 Query: 892 EHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGR 951 + +K ++L VK + G+ N+G ALD+ F ++ GSR+E+GV Q LVL+ AG Sbjct: 92 TYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGP 151 Query: 952 SSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVN 1011 SSD + LKQ+ V F A+ A AEL+ I + GDL +++ Sbjct: 152 SSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLP 211 Query: 1012 LLKSVHNG-----APAPVS-----GEKDVVFLLDGSEGVR-SGFPLLKEFVQRVVESLDV 1060 + V P V+ ++D+VFL+DGS + + F +++F+ +V++ L++ Sbjct: 212 YIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEI 271 Query: 1061 GQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNIL 1120 GQD ++VAV QY+D RPEFY N++ K++V+ AVR++ L G TG+AL+FV N+ Sbjct: 272 GQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLF 331 Query: 1121 VSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISF 1180 SSAG R EG+P+LL+++T +S D++ P+ +KR + IG AD E++ I+F Sbjct: 332 TSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAF 391 Query: 1181 IPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGV-GGKRDVVFLID 1239 V IP + +Q ++ L P+ +P V KRD++FL+D Sbjct: 392 DSSL-VFIPAEFRAAPLQGMLP-----------GLLAPLRTLSGTPEVHSNKRDIIFLLD 439 Query: 1240 GSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNA 1298 GS + G F YVR + LV+ LD+G D RV ++QFSD P EF LN + +K ++ Sbjct: 440 GSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGH 499 Query: 1299 VQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVE 1358 +++L+ +GG +N G+AL YV N F GSRI E VPQ L+L+++G+S+D A Sbjct: 500 LRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANA 559 Query: 1359 LKQFGVAPFTI-ARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQ 1417 L + G+ F + A A++ EL +I+ +P V+ + F LP+L Q+L+ P+TT S ++ Sbjct: 560 LTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVE 619 Query: 1418 KLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGV 1477 ++ P A DI+FL D S + F +RDF+ +I+ LN+ P R+ V Sbjct: 620 EV-------PLAQPESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAV 671 Query: 1478 VQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIE 1537 Q+S+DV E ++S+ +L+ ++R++++ G LN G AL++ R +FVKSAGSRIE Sbjct: 672 AQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIE 731 Query: 1538 DGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVR 1597 DGV Q LVL++ G+S D V A ++ SG+V +N D EL+ I P + Sbjct: 732 DGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAE 791 Query: 1598 EFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQE 1657 ++ ++ +I+N S AP P + D+VFLLDGS R F Sbjct: 792 SLPKIGDLHPQIVNLL-KSVHNGAPA---------PVSGEKDVVFLLDGSEGVR-SGFPL 840 Query: 1658 VLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHA 1717 + FV +V+++ D ++V +VQY+ EF+L + K+ +++A+ ++ GG Sbjct: 841 LKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTP 900 Query: 1718 NTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVG 1777 NT LE + N V AGSR+ + VPQ+ V+T +S +D ++ S+ + + G +G Sbjct: 901 NTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIG 960 Query: 1778 VRNIDSEEVGKI------ASNSATAFRVGNVQE-----LSELSEQVLETLHDAMHETLCP 1826 + N D E+ I A T ++G VQ+ +++L+ + L L + P Sbjct: 961 IGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSP 1020 Query: 1827 GVTDAAKACNLDVILGFDGSR 1847 GV DV+ DGS+ Sbjct: 1021 GV-----GGKRDVVFLIDGSQ 1036 Score = 378 bits (971), Expect = e-104 Identities = 265/819 (32%), Positives = 412/819 (50%), Gaps = 43/819 (5%) Query: 1233 DVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSS 1291 D++FLIDGS + G F + + L++ L +G RV V+QFSD+P+ F L+ +S+ Sbjct: 36 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 95 Query: 1292 KDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDE 1351 K +V AV+ L GG N+G AL++V N F R GSR+EEGVPQ LVLIS+G S DE Sbjct: 96 KAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDE 155 Query: 1352 VDDPAVELKQFGVAPFTI-ARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITT 1410 + V LKQ V F + A+ A + EL I+ VF+V FR L++KLL I Sbjct: 156 IRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIVG 215 Query: 1411 LTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGP 1470 + I +L +E + DIVFL+D S + F IRDF++++++RL IG Sbjct: 216 VAQRHI--VLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQ 273 Query: 1471 SKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVK 1530 ++V V Q+++ V PEFY T+ ++ V+ A+R+++ GS L TG AL+FV NLF Sbjct: 274 DLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTS 333 Query: 1531 SAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDP 1590 SAG R +G+P+ LVL+ GGKS D++S+ AQ ++ S I++ +G++ D+ EL+ I D Sbjct: 334 SAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDS 393 Query: 1591 RLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINF 1650 LVF EFR P + P P TP K DI+FLLDGS N Sbjct: 394 SLVFIPAEFRAAP------LQGMLPGLLAPLRTLSGTP---EVHSNKRDIIFLLDGSANV 444 Query: 1651 RRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVV 1710 + +F V FV +V+++ D+I+VGLVQ++ P EF L + TK I+ + ++ Sbjct: 445 GKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQ 504 Query: 1711 YKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRG 1770 +GG NT L ++ NHF GSR+ + VPQ+ ++T G+S + + ALT+ G Sbjct: 505 LQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAG 564 Query: 1771 VKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLETLHDAMHETLCPGVTD 1830 + F VG + E+ +IA N + + + + L L +Q+++ L + + V Sbjct: 565 ILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGV-EEVPL 623 Query: 1831 AAKACNLDVILGFDGSRD-QNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSV 1889 A D++ FDGS + F + F K+ LN V G R++V Sbjct: 624 AQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELN-------VKPEG-----TRIAV 671 Query: 1890 VANTPSGPVEA-FDFDEYQPEMLEKFRNMRSQH------PYVLTEDTLKVYLNKFRQSSP 1942 + VE+ FD + +PE+L + M+ + Y L +++ Sbjct: 672 AQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIE 731 Query: 1943 DSV-KVVIHFTDGADGDLADLHRASENLRQEGVRALILVGLERVVNLERLMHLEFGRGFM 2001 D V + ++ G D D + NL+Q GV I + + L + F+ Sbjct: 732 DGVLQFLVLLVAGRSSDRVD--GPASNLKQSGVVPFIFQA--KNADPAELEQIVLSPAFI 787 Query: 2002 YDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQR 2040 L L +L Q+ N+ + G P SG++ Sbjct: 788 ----LAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEK 822 Score = 229 bits (585), Expect = 3e-59 Identities = 163/527 (30%), Positives = 259/527 (49%), Gaps = 38/527 (7%) Query: 1433 DAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKT 1492 D+ADI+FLID S FA I DF+ ++ +L IG ++RVGVVQFS++ F L T Sbjct: 33 DSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDT 92 Query: 1493 YRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKS 1552 Y ++A VL A++ L GG N G AL+FV N F ++ GSR+E+GVPQ LVL+ G S Sbjct: 93 YSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPS 152 Query: 1553 QDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNS 1612 D++ ++ + + S G+G + R ELQ I D LVFTV EFR +++E+++ Sbjct: 153 SDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLL-- 210 Query: 1613 FGPSAATPAPPGVDTPPPSRP----EKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDT 1668 P A + PP+ E K DIVFL+DGS +F + F+++++ Sbjct: 211 --PYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQR 268 Query: 1669 VYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRV 1728 + D IQV + QY EF+ TKR++I A+ K+ G T L+ +R Sbjct: 269 LEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRN 328 Query: 1729 NHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGK 1788 N F AG R + +P++ +ITGGKS+++ + L + + FA+G + D E+ + Sbjct: 329 NLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEE 388 Query: 1789 IASNSA-----TAFRVGNVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGF 1843 IA +S+ FR +Q + L TL T + D+I Sbjct: 389 IAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSG----------TPEVHSNKRDIIFLL 438 Query: 1844 DGSRDQNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDF 1903 DGS + V + F D ++N ++ + + +RV +V + + PV F Sbjct: 439 DGSAN----VGKTNFPYVRDFVMNLVNSLDI------GNDNIRVGLVQFSDT-PVTEFSL 487 Query: 1904 DEYQ--PEMLEKFRNMRSQHPYVLTEDTL--KVYLNKFRQSSPDSVK 1946 + YQ ++L R ++ Q L + VY N F ++ ++ Sbjct: 488 NTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIR 534 Score = 79.0 bits (193), Expect = 7e-14 Identities = 95/406 (23%), Positives = 176/406 (43%), Gaps = 57/406 (14%) Query: 2393 PLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNN 2452 PL P ++ F D S + F +RD + I+++L + P G R+AV Y++ Sbjct: 622 PLAQPESKRDILFLFDGSANL-VGQFPVVRDFLYKIIDELNVK----PEGTRIAVAQYSD 676 Query: 2453 EVTTEIRFADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTF-----KRVRNGFL 2507 +V E RF + + K +L+ +K +++ T K +L A+ + R F R+ +G L Sbjct: 677 DVKVESRFDEHQSKPEILNLVKRMKIK-TGKALNLGYALDYAQRYIFVKSAGSRIEDGVL 735 Query: 2508 MRKVAVFFSNTPTRASPQLREAVLKLSDAGITP-LFLTRQEDRQLINALQINNTAVGHAL 2566 V + R+S ++ L +G+ P +F + D + + ++ + A Sbjct: 736 QFLVLL----VAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAE 791 Query: 2567 VLPAGRDLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDS 2626 LP DL + N+L S + A + D+ F+LD Sbjct: 792 SLPKIGDLHPQIVNLL---------------------KSVHNGAPAPVSGEKDVVFLLDG 830 Query: 2627 AETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVE 2686 +E F +K+++ +V LD+ D RVAVVQ++ + E Sbjct: 831 SEGVR-SGFPLLKEFVQRVVESLDVGQDR------VRVAVVQYSDR----------TRPE 873 Query: 2687 FSLTDYGSKEKLVDFLSRGMTQLQG-TRALGSAIEYTIENVFESAPNPRDLKIVVLMLTG 2745 F L Y +K+ +V+ + R +T L G T G+A+E+ + N+ S+ R + V +L Sbjct: 874 FYLNSYMNKQDVVNAV-RQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIV 932 Query: 2746 EVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPN 2791 ++ ++ + + K G + +GIG +I E+ T + P+ Sbjct: 933 LTADRSGDDVRNPSVVVKRGGAVPIGIGIG-NADITEMQTISFIPD 977 Score = 58.9 bits (141), Expect = 8e-08 Identities = 81/370 (21%), Positives = 155/370 (41%), Gaps = 52/370 (14%) Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 2461 ++ F +D S F + D +++++ L I RV VV +++E T Sbjct: 36 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQI----RVGVVQFSDEPRTMFSLD 91 Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFL---MRKVAVFFSNT 2518 K+ +L +K L A + ++ A+ FV N F R + + +V V S Sbjct: 92 TYSTKAQVLGAVKALGFA-GGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAG 150 Query: 2519 PTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALV--LPAGRDLTD 2576 P+ S ++R V+ L A + L Q + ++ + A LV +P R D Sbjct: 151 PS--SDEIRYGVVALKQASVFSFGL----GAQAASRAELQHIATDDNLVFTVPEFRSFGD 204 Query: 2577 FLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDI---DMAFILDSAETTTLF 2633 E +L V G + +++ D+ F++D + L Sbjct: 205 LQEKLLPYIV-----------GVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLA 253 Query: 2634 QFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYG 2693 FN ++ +IA ++++L++ D +VAV Q+A + V+ EF + Sbjct: 254 NFNAIRDFIAKVIQRLEIGQD------LIQVAVAQYADT----------VRPEFYFNTHP 297 Query: 2694 SKEKLVDFLSRGMTQLQGTRA-LGSAIEYTIENVFESAPNPRDL----KIVVLMLTGEVP 2748 +K +++ + R M L G+ GSA+++ N+F S+ R K++VL+ G+ Sbjct: 298 TKREVITAV-RKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSL 356 Query: 2749 EQQLEEAQRV 2758 ++ + AQ + Sbjct: 357 DEISQPAQEL 366 Score = 55.5 bits (132), Expect = 8e-07 Identities = 77/349 (22%), Positives = 145/349 (41%), Gaps = 42/349 (12%) Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 2461 ++ F LD S V + F +RD V+++VN L I N RV +V +++ TE Sbjct: 433 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDN----IRVGLVQFSDTPVTEFSLN 488 Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKV-AVFFSNTPT 2520 + KS +L ++ LQ+ S + +A+S+V N F + V + T Sbjct: 489 TYQTKSDILGHLRQLQLQGGSGLNT-GSALSYVYANHFTEAGGSRIREHVPQLLLLLTAG 547 Query: 2521 RASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLEN 2580 ++ +A L+ AGI LT N ++ A +LV +L + Sbjct: 548 QSEDSYLQAANALTRAGI----LTFCVGASQANKAELEQIAFNPSLV---------YLMD 594 Query: 2581 VLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKK 2640 + L I P + S + A + D+ F+ D + + QF ++ Sbjct: 595 DFSSLPALPQQLIQPLTTYVS--GGVEEVPLAQPESKRDILFLFDGS-ANLVGQFPVVRD 651 Query: 2641 YIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVD 2700 ++ ++ +L++ P+ R+AV Q++ VKVE ++ SK ++++ Sbjct: 652 FLYKIIDELNVKPEG------TRIAVAQYSDD----------VKVESRFDEHQSKPEILN 695 Query: 2701 FLSRGMTQLQGTRALGSAIEYTIENVFESAPNPR----DLKIVVLMLTG 2745 + R + LG A++Y +F + R L+ +VL++ G Sbjct: 696 LVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAG 744 Score = 43.1 bits (100), Expect = 0.004 Identities = 93/421 (22%), Positives = 158/421 (37%), Gaps = 70/421 (16%) Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 2461 ++ F +D S + F +RD + ++ L I + +VAV Y + V E F Sbjct: 239 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLI----QVAVAQYADTVRPEFYFN 294 Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFK-----RVRNGFLMRKVAVFFS 2516 K ++ ++ ++ L +A+ FV N F R G V + Sbjct: 295 THPTKREVITAVRKMK-PLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLI--- 350 Query: 2517 NTPTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALV-LPA---GR 2572 T ++ ++ + +L + I + + Q ++ A +LV +PA Sbjct: 351 -TGGKSLDEISQPAQELKRSSIMAFAIGNKGADQA----ELEEIAFDSSLVFIPAEFRAA 405 Query: 2573 DLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTL 2632 L L +L L S P + D+ F+LD + Sbjct: 406 PLQGMLPGLLAPLRTL------------SGTPEVHSNKR-------DIIFLLDGSANVGK 446 Query: 2633 FQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDY 2692 F ++ ++ LV LD+ D RV +VQ + + PV EFSL Y Sbjct: 447 TNFPYVRDFVMNLVNSLDIGNDN------IRVGLVQFSDT---------PV-TEFSLNTY 490 Query: 2693 GSKEKLVDFLSRGMTQLQGTRAL--GSAIEYTIENVFESAPNPR---DLKIVVLMLTGEV 2747 +K ++ L + QLQG L GSA+ Y N F A R + ++L+LT Sbjct: 491 QTKSDILGHLRQ--LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQ 548 Query: 2748 PEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKLVDKSTELNEE 2807 E +A + +A G +G + N E+ A P+ V+ L+D + L Sbjct: 549 SEDSYLQAANALTRA---GILTFCVG-ASQANKAELEQIAFNPSLVY--LMDDFSSLPAL 602 Query: 2808 P 2808 P Sbjct: 603 P 603 Score = 36.6 bits (83), Expect = 0.41 Identities = 29/150 (19%), Positives = 69/150 (46%), Gaps = 7/150 (4%) Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 2461 ++ F +D S+ + F +R ++ +V+ L + RVAV+ ++++ E Sbjct: 1027 DVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDT----TRVAVIQFSDDPKVEFLLN 1081 Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPT- 2520 K + + ++ L+ +Q ++ A+ +V+RN FKR + V F + Sbjct: 1082 AHSSKDEVQNAVQRLRPK-GGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSG 1140 Query: 2521 RASPQLREAVLKLSDAGITPLFLTRQEDRQ 2550 ++ ++ + ++L G+ P + R D++ Sbjct: 1141 KSDDEVDDPAVELKQFGVAPFTIARNADQE 1170 >gi|240255542 alpha 3 type VI collagen isoform 2 precursor [Homo sapiens] Length = 1036 Score = 1910 bits (4947), Expect = 0.0 Identities = 993/1001 (99%), Positives = 997/1001 (99%), Gaps = 1/1001 (0%) Query: 438 VIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEF 497 VIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEF Sbjct: 31 VIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEF 90 Query: 498 YFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLIT 557 YFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLIT Sbjct: 91 YFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLIT 150 Query: 558 GGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGML 617 GGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGML Sbjct: 151 GGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGML 210 Query: 618 PGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIR 677 PGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIR Sbjct: 211 PGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIR 270 Query: 678 VGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGS 737 VGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGS Sbjct: 271 VGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGS 330 Query: 738 RIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVY 797 RIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVY Sbjct: 331 RIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVY 390 Query: 798 LMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANLVGQFPVVRD 857 LMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANLVGQFPVVRD Sbjct: 391 LMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANLVGQFPVVRD 450 Query: 858 FLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLG 917 FLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLG Sbjct: 451 FLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLG 510 Query: 918 YALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKN 977 YALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKN Sbjct: 511 YALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKN 570 Query: 978 ADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGS 1037 ADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGS Sbjct: 571 ADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGS 630 Query: 1038 EGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQ 1097 EGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQ Sbjct: 631 EGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQ 690 Query: 1098 LTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKR 1157 LTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKR Sbjct: 691 LTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKR 750 Query: 1158 GGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQ 1217 GGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQ Sbjct: 751 GGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQ 810 Query: 1218 PVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFS 1277 PVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFS Sbjct: 811 PVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFS 870 Query: 1278 DDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVP 1337 DDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVP Sbjct: 871 DDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVP 930 Query: 1338 QFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVKISLSPEYVFSVSTFREL 1397 QFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVKISLSPEYVFSVSTFREL Sbjct: 931 QFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVKISLSPEYVFSVSTFREL 990 Query: 1398 PSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIV 1438 PSLEQKLLTPITTLTSEQIQKLLASTRYPPP E A++++ Sbjct: 991 PSLEQKLLTPITTLTSEQIQKLLASTRYPPPG-EMGASEVL 1030 Score = 699 bits (1805), Expect = 0.0 Identities = 404/1024 (39%), Positives = 610/1024 (59%), Gaps = 40/1024 (3%) Query: 1 MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVRE 60 MRKHRHLPLVAVFCLFLSGFPTTHAQQQQA ++ DI+FLVD S +G +F +R+ Sbjct: 1 MRKHRHLPLVAVFCLFLSGFPTTHAQQQQAVIEVNKR-DIVFLVDGSSALGLANFNAIRD 59 Query: 61 FLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTN-QTG 119 F+ V++ L +G++ A+ Q+ EF NT+ TK+EV++ + M + G+ TG Sbjct: 60 FIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTG 119 Query: 120 KGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVED 179 L+++ + T +AG RA +G+P+++V++T G S D ++ P+ ELK + + FAIG + Sbjct: 120 SALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKG 179 Query: 180 ADEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHS-SVSPERAGDTETLKDITAQ 238 AD+ L+EIA + + + L ++ L++ + + S +PE Sbjct: 180 ADQAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPE-----------VHS 228 Query: 239 DSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDT 298 + DIIFL+DGS N G NF + DF++NL+ L IG IRVG+VQFSD P T FSL+T Sbjct: 229 NKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNT 288 Query: 299 YSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPS 358 Y TK+ +LG ++ L GG N G AL +V NHFT AGGSR+ E VPQ+L+L++AG S Sbjct: 289 YQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQS 348 Query: 359 SDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLL-- 416 D AL +A + +F +GA A++AEL+ IA + +LV+ + +F S L ++L+ Sbjct: 349 EDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQP 408 Query: 417 --PYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQR 474 Y+ G + + +P +KRDI+FL DGS+ L + F +RDF+ K+I Sbjct: 409 LTTYVSGGVEEVPLAQPE---------SKRDILFLFDGSANL-VGQFPVVRDFLYKIIDE 458 Query: 475 LEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRN 534 L + + ++AVAQY+D V+ E F+ H +K E++ V++MK G AL G ALD+ + Sbjct: 459 LNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQR 518 Query: 535 NLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEE 594 +F SAG R +G+ + LVL+ G+S D + PA LK+S ++ F K AD AELE+ Sbjct: 519 YIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQ 578 Query: 595 IAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTL-SGTPEVHSNKRDIIFLLDGSANVGKT 653 I S FI A + + P ++ L+++ +G P S ++D++FLLDGS V ++ Sbjct: 579 IVL--SPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGV-RS 635 Query: 654 NFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQG 713 FP +++FV +V SLD+G D +RV +VQ+SD EF LN+Y K D++ +RQL L G Sbjct: 636 GFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLG 695 Query: 714 GSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILT 773 G NTG+AL +V N + GSRI E VPQLL++LTA +S D + + R G + Sbjct: 696 GPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVP 755 Query: 774 FCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEV-PLAQP 832 +G A+ E++ I+F P + F L + Q + + +T + + P+ QP Sbjct: 756 IGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQP 815 Query: 833 ------ESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKV 886 KRD++FL DGS + +F VR + +++D L+V + TR+AV Q+SDD KV Sbjct: 816 LPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKV 875 Query: 887 ESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVL 946 E + H SK E+ N V+R++ K G+ +N+G AL+Y R IF + GSRIE+GV QFLVL Sbjct: 876 EFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVL 935 Query: 947 LVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLH 1006 + +G+S D VD PA LKQ GV PF A+NAD EL +I LSP ++ + + ++ L Sbjct: 936 ISSGKSDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSPEYVFSVSTFRELPSLE 994 Query: 1007 PQIV 1010 +++ Sbjct: 995 QKLL 998 Score = 641 bits (1653), Expect = 0.0 Identities = 384/989 (38%), Positives = 572/989 (57%), Gaps = 34/989 (3%) Query: 834 SKRDILFLFDGSANL-VGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDE 892 +KRDI+FL DGS+ L + F +RDF+ K+I L + + ++AVAQY+D V+ E F+ Sbjct: 35 NKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNT 94 Query: 893 HQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRS 952 H +K E++ V++MK G AL G ALD+ + +F SAG R +G+ + LVL+ G+S Sbjct: 95 HPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKS 154 Query: 953 SDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVL--SPAFILAAESLPKIGDLHPQIV 1010 D + PA LK+S ++ F K AD AELE+I S FI A + + P ++ Sbjct: 155 LDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLL 214 Query: 1011 NLLKSVHNGAPAPVSGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAV 1069 L+++ +G P S ++D++FLLDGS V ++ FP +++FV +V SLD+G D +RV + Sbjct: 215 APLRTL-SGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGL 273 Query: 1070 VQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRIT 1129 VQ+SD EF LN+Y K D++ +RQL L GG NTG+AL +V N + GSRI Sbjct: 274 VQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIR 333 Query: 1130 EGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIP 1189 E VPQLL++LTA +S D + + R G + +G A+ E++ I+F P + Sbjct: 334 EHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMD 393 Query: 1190 TFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQ 1249 F L + Q + + +T + + P+ QP KRD++FL DGS + +F Sbjct: 394 DFSSLPALPQQLIQPLTTYVSGGVEEV-PLAQP------ESKRDILFLFDGSANLVGQFP 446 Query: 1250 YVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQ 1309 VR + +++D L+V + TR+AV Q+SDD KVE + H SK E+ N V+R++ K G+ Sbjct: 447 VVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKA 506 Query: 1310 INVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI 1369 +N+G AL+Y R IF + GSRIE+GV QFLVL+ +G+S D VD PA LKQ GV PF Sbjct: 507 LNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIF 566 Query: 1370 -ARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPP 1428 A+NAD EL +I LSP ++ + + ++ L QI LL S P Sbjct: 567 QAKNADPAELEQIVLSPAFILAAESLPKIGDLHP------------QIVNLLKSVHNGAP 614 Query: 1429 AVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEF 1488 A S D+VFL+D SEGVR GF +++FV R+V L++G +VRV VVQ+S+ PEF Sbjct: 615 APVSGEKDVVFLLDGSEGVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEF 673 Query: 1489 YLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVL 1548 YL +Y ++ V++A+R+L L GG NTG ALEFV RN+ V SAGSRI +GVPQ L+++ Sbjct: 674 YLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLT 733 Query: 1549 GGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIE-- 1606 +S DDV + V++ G V +G+G N D TE+QTI+ P + FR+L ++ Sbjct: 734 ADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQV 793 Query: 1607 --ERIMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSE 1664 ER+ + P V P PS K D+VFL+DGS FQ V + Sbjct: 794 ISERVTQLTREELSRLQP--VLQPLPSPGVGGKRDVVFLIDGS-QSAGPEFQYVRTLIER 850 Query: 1665 IVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLE 1724 +VD + D+ +V ++Q++ DP EF L S+K ++ +A+ ++ KGGR N LE Sbjct: 851 LVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALE 910 Query: 1725 HLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSE 1784 ++ N F GSR+++ VPQ +I+ GKS ++ D ++ L Q GV F + RN D E Sbjct: 911 YVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI-ARNADQE 969 Query: 1785 EVGKIASNSATAFRVGNVQELSELSEQVL 1813 E+ KI+ + F V +EL L +++L Sbjct: 970 ELVKISLSPEYVFSVSTFRELPSLEQKLL 998 Score = 458 bits (1178), Expect = e-128 Identities = 282/836 (33%), Positives = 459/836 (54%), Gaps = 51/836 (6%) Query: 1027 EKDVVFLLDGSEGVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSY 1085 ++D+VFL+DGS + + F +++F+ +V++ L++GQD ++VAV QY+D RPEFY N++ Sbjct: 36 KRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTH 95 Query: 1086 MNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSG 1145 K++V+ AVR++ L G TG+AL+FV N+ SSAG R EG+P+LL+++T +S Sbjct: 96 PTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSL 155 Query: 1146 DDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERV 1205 D++ P+ +KR + IG AD E++ I+F V IP + +Q ++ Sbjct: 156 DEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSL-VFIPAEFRAAPLQGMLP--- 211 Query: 1206 TQLTREELSRLQPVLQPLPSPGV-GGKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLD 1263 L P+ +P V KRD++FL+DGS + G F YVR + LV+ LD Sbjct: 212 --------GLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD 263 Query: 1264 VGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNI 1323 +G D RV ++QFSD P EF LN + +K ++ +++L+ +GG +N G+AL YV N Sbjct: 264 IGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANH 323 Query: 1324 FKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKIS 1382 F GSRI E VPQ L+L+++G+S+D A L + G+ F + A A++ EL +I+ Sbjct: 324 FTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIA 383 Query: 1383 LSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLID 1442 +P V+ + F LP+L Q+L+ P+TT S ++++ P A DI+FL D Sbjct: 384 FNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEV-------PLAQPESKRDILFLFD 436 Query: 1443 SSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDA 1502 S + F +RDF+ +I+ LN+ P R+ V Q+S+DV E ++S+ +L+ Sbjct: 437 GSANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNL 495 Query: 1503 IRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQV 1562 ++R++++ G LN G AL++ R +FVKSAGSRIEDGV Q LVL++ G+S D V A Sbjct: 496 VKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASN 555 Query: 1563 IRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAP 1622 ++ SG+V +N D EL+ I P + ++ ++ +I+N S AP Sbjct: 556 LKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLL-KSVHNGAP 614 Query: 1623 PGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQ 1682 P + D+VFLLDGS R F + FV +V+++ D ++V +VQ Sbjct: 615 A---------PVSGEKDVVFLLDGSEGVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQ 664 Query: 1683 YNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQR 1742 Y+ EF+L + K+ +++A+ ++ GG NT LE + N V AGSR+ + Sbjct: 665 YSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEG 724 Query: 1743 VPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKI------ASNSATA 1796 VPQ+ V+T +S +D ++ S+ + + G +G+ N D E+ I A T Sbjct: 725 VPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTF 784 Query: 1797 FRVGNVQE-----LSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGSR 1847 ++G VQ+ +++L+ + L L + PGV DV+ DGS+ Sbjct: 785 RQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGV-----GGKRDVVFLIDGSQ 835 Score = 258 bits (660), Expect = 5e-68 Identities = 186/620 (30%), Positives = 302/620 (48%), Gaps = 39/620 (6%) Query: 1430 VESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFY 1489 +E + DIVFL+D S + F IRDF++++++RL IG ++V V Q+++ V PEFY Sbjct: 32 IEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFY 91 Query: 1490 LKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLG 1549 T+ ++ V+ A+R+++ GS L TG AL+FV NLF SAG R +G+P+ LVL+ G Sbjct: 92 FNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITG 151 Query: 1550 GKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERI 1609 GKS D++S+ AQ ++ S I++ +G++ D+ EL+ I D LVF EFR P Sbjct: 152 GKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAP------ 205 Query: 1610 MNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTV 1669 + P P TP K DI+FLLDGS N + +F V FV +V+++ Sbjct: 206 LQGMLPGLLAPLRTLSGTP---EVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSL 262 Query: 1670 YEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVN 1729 D+I+VGLVQ++ P EF L + TK I+ + ++ +GG NT L ++ N Sbjct: 263 DIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYAN 322 Query: 1730 HFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKI 1789 HF GSR+ + VPQ+ ++T G+S + + ALT+ G+ F VG + E+ +I Sbjct: 323 HFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQI 382 Query: 1790 ASNSATAFRVGNVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGSRD- 1848 A N + + + + L L +Q+++ L + + V A D++ FDGS + Sbjct: 383 AFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGV-EEVPLAQPESKRDILFLFDGSANL 441 Query: 1849 QNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEA-FDFDEYQ 1907 F + F K+ LN V G R++V + VE+ FD + + Sbjct: 442 VGQFPVVRDFLYKIIDELN-------VKPEG-----TRIAVAQYSDDVKVESRFDEHQSK 489 Query: 1908 PEMLEKFRNMRSQH------PYVLTEDTLKVYLNKFRQSSPDSV-KVVIHFTDGADGDLA 1960 PE+L + M+ + Y L +++ D V + ++ G D Sbjct: 490 PEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRV 549 Query: 1961 DLHRASENLRQEGVRALILVGLERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQ 2020 D + NL+Q GV I + + L + F+ L L +L Q Sbjct: 550 D--GPASNLKQSGVVPFIFQA--KNADPAELEQIVLSPAFI----LAAESLPKIGDLHPQ 601 Query: 2021 LDNIAEKACCGVPCKCSGQR 2040 + N+ + G P SG++ Sbjct: 602 IVNLLKSVHNGAPAPVSGEK 621 Score = 217 bits (553), Expect = 1e-55 Identities = 141/404 (34%), Positives = 218/404 (53%), Gaps = 11/404 (2%) Query: 32 VKNGAAA------DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNG 85 V NGA A D++FL+D S + F L++EF+ VV+SL VG++ A+VQ++ Sbjct: 609 VHNGAPAPVSGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSD 667 Query: 86 NPHTEFLLNTYRTKQEVLSHISNMSYIGG-TNQTGKGLEYIMQSHLTKAAGSRAGDGVPQ 144 EF LN+Y KQ+V++ + ++ +GG T TG LE+++++ L +AGSR +GVPQ Sbjct: 668 RTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQ 727 Query: 145 VIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEP-LNMHMFNLENF 203 +++VLT S D + PS +K IG+ +AD ++ I+ P + + Sbjct: 728 LLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQL 787 Query: 204 TSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAVILD 263 ++ ++ V+ + + L D++FLIDGS + G F + Sbjct: 788 GTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGP-EFQYVRT 846 Query: 264 FLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIG 323 + L++ L +G RV V+QFSD+P+ F L+ +S+K +V AV+ L GG N+G Sbjct: 847 LIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVG 906 Query: 324 LALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQA 383 AL++V N F R GSR+EEGVPQ LVLIS+G S DE+ V LKQ V F + A+ Sbjct: 907 NALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI-ARN 965 Query: 384 ASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIVGVAQRHI 427 A + EL I+ VF+V FR L++KLL I + I Sbjct: 966 ADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQI 1009 Score = 79.0 bits (193), Expect = 7e-14 Identities = 95/406 (23%), Positives = 176/406 (43%), Gaps = 57/406 (14%) Query: 2393 PLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNN 2452 PL P ++ F D S + F +RD + I+++L + P G R+AV Y++ Sbjct: 421 PLAQPESKRDILFLFDGSANL-VGQFPVVRDFLYKIIDELNVK----PEGTRIAVAQYSD 475 Query: 2453 EVTTEIRFADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTF-----KRVRNGFL 2507 +V E RF + + K +L+ +K +++ T K +L A+ + R F R+ +G L Sbjct: 476 DVKVESRFDEHQSKPEILNLVKRMKIK-TGKALNLGYALDYAQRYIFVKSAGSRIEDGVL 534 Query: 2508 MRKVAVFFSNTPTRASPQLREAVLKLSDAGITP-LFLTRQEDRQLINALQINNTAVGHAL 2566 V + R+S ++ L +G+ P +F + D + + ++ + A Sbjct: 535 QFLVLL----VAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAE 590 Query: 2567 VLPAGRDLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDS 2626 LP DL + N+L S + A + D+ F+LD Sbjct: 591 SLPKIGDLHPQIVNLL---------------------KSVHNGAPAPVSGEKDVVFLLDG 629 Query: 2627 AETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVE 2686 +E F +K+++ +V LD+ D RVAVVQ++ + E Sbjct: 630 SEGVR-SGFPLLKEFVQRVVESLDVGQDR------VRVAVVQYSDR----------TRPE 672 Query: 2687 FSLTDYGSKEKLVDFLSRGMTQLQG-TRALGSAIEYTIENVFESAPNPRDLKIVVLMLTG 2745 F L Y +K+ +V+ + R +T L G T G+A+E+ + N+ S+ R + V +L Sbjct: 673 FYLNSYMNKQDVVNAV-RQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIV 731 Query: 2746 EVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPN 2791 ++ ++ + + K G + +GIG +I E+ T + P+ Sbjct: 732 LTADRSGDDVRNPSVVVKRGGAVPIGIGIG-NADITEMQTISFIPD 776 Score = 55.5 bits (132), Expect = 8e-07 Identities = 77/349 (22%), Positives = 145/349 (41%), Gaps = 42/349 (12%) Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 2461 ++ F LD S V + F +RD V+++VN L I N RV +V +++ TE Sbjct: 232 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDN----IRVGLVQFSDTPVTEFSLN 287 Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKV-AVFFSNTPT 2520 + KS +L ++ LQ+ S + +A+S+V N F + V + T Sbjct: 288 TYQTKSDILGHLRQLQLQGGSGLNT-GSALSYVYANHFTEAGGSRIREHVPQLLLLLTAG 346 Query: 2521 RASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLEN 2580 ++ +A L+ AGI LT N ++ A +LV +L + Sbjct: 347 QSEDSYLQAANALTRAGI----LTFCVGASQANKAELEQIAFNPSLV---------YLMD 393 Query: 2581 VLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKK 2640 + L I P + S + A + D+ F+ D + + QF ++ Sbjct: 394 DFSSLPALPQQLIQPLTTYVS--GGVEEVPLAQPESKRDILFLFDGS-ANLVGQFPVVRD 450 Query: 2641 YIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVD 2700 ++ ++ +L++ P+ R+AV Q++ VKVE ++ SK ++++ Sbjct: 451 FLYKIIDELNVKPEG------TRIAVAQYSDD----------VKVESRFDEHQSKPEILN 494 Query: 2701 FLSRGMTQLQGTRALGSAIEYTIENVFESAPNPR----DLKIVVLMLTG 2745 + R + LG A++Y +F + R L+ +VL++ G Sbjct: 495 LVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAG 543 Score = 43.9 bits (102), Expect = 0.003 Identities = 36/145 (24%), Positives = 73/145 (50%), Gaps = 22/145 (15%) Query: 2619 DMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNA 2678 D+ F++D + L FN ++ +IA ++++L++ D +VAV Q+A + Sbjct: 38 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQD------LIQVAVAQYADT------ 85 Query: 2679 SMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRA-LGSAIEYTIENVFESAPNPRDL- 2736 V+ EF + +K +++ + R M L G+ GSA+++ N+F S+ R Sbjct: 86 ----VRPEFYFNTHPTKREVITAV-RKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAE 140 Query: 2737 ---KIVVLMLTGEVPEQQLEEAQRV 2758 K++VL+ G+ ++ + AQ + Sbjct: 141 GIPKLLVLITGGKSLDEISQPAQEL 165 Score = 43.1 bits (100), Expect = 0.004 Identities = 93/421 (22%), Positives = 158/421 (37%), Gaps = 70/421 (16%) Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 2461 ++ F +D S + F +RD + ++ L I + +VAV Y + V E F Sbjct: 38 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLI----QVAVAQYADTVRPEFYFN 93 Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFK-----RVRNGFLMRKVAVFFS 2516 K ++ ++ ++ L +A+ FV N F R G V + Sbjct: 94 THPTKREVITAVRKMK-PLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLI--- 149 Query: 2517 NTPTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALV-LPA---GR 2572 T ++ ++ + +L + I + + Q ++ A +LV +PA Sbjct: 150 -TGGKSLDEISQPAQELKRSSIMAFAIGNKGADQA----ELEEIAFDSSLVFIPAEFRAA 204 Query: 2573 DLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTL 2632 L L +L L S P + D+ F+LD + Sbjct: 205 PLQGMLPGLLAPLRTL------------SGTPEVHSNKR-------DIIFLLDGSANVGK 245 Query: 2633 FQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDY 2692 F ++ ++ LV LD+ D RV +VQ + + PV EFSL Y Sbjct: 246 TNFPYVRDFVMNLVNSLDIGNDN------IRVGLVQFSDT---------PV-TEFSLNTY 289 Query: 2693 GSKEKLVDFLSRGMTQLQGTRAL--GSAIEYTIENVFESAPNPR---DLKIVVLMLTGEV 2747 +K ++ L + QLQG L GSA+ Y N F A R + ++L+LT Sbjct: 290 QTKSDILGHLRQ--LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQ 347 Query: 2748 PEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKLVDKSTELNEE 2807 E +A + +A G +G + N E+ A P+ V+ L+D + L Sbjct: 348 SEDSYLQAANALTRA---GILTFCVG-ASQANKAELEQIAFNPSLVY--LMDDFSSLPAL 401 Query: 2808 P 2808 P Sbjct: 402 P 402 Score = 36.6 bits (83), Expect = 0.41 Identities = 29/150 (19%), Positives = 69/150 (46%), Gaps = 7/150 (4%) Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 2461 ++ F +D S+ + F +R ++ +V+ L + RVAV+ ++++ E Sbjct: 826 DVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDT----TRVAVIQFSDDPKVEFLLN 880 Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPT- 2520 K + + ++ L+ +Q ++ A+ +V+RN FKR + V F + Sbjct: 881 AHSSKDEVQNAVQRLRPK-GGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSG 939 Query: 2521 RASPQLREAVLKLSDAGITPLFLTRQEDRQ 2550 ++ ++ + ++L G+ P + R D++ Sbjct: 940 KSDDEVDDPAVELKQFGVAPFTIARNADQE 969 >gi|156616290 collagen type VI alpha 6 [Homo sapiens] Length = 2263 Score = 1144 bits (2960), Expect = 0.0 Identities = 730/2191 (33%), Positives = 1148/2191 (52%), Gaps = 116/2191 (5%) Query: 639 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQT 698 D++FL+D S +G +FP+V+ F+ +++SL I D RV L Q+SD +EF L+T++ Sbjct: 27 DVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFKG 86 Query: 699 KSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDS 758 +S +L HLR+ G L G AL + +F+ R ++ P +L++L + +SED+ Sbjct: 87 RSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVLASSESEDN 146 Query: 759 YLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYL--MDDFSSLPALPQQLIQPL 816 +A+ AL + G+ VG +A++ L+ +A + L + D S +I+ + Sbjct: 147 VEEASKALRKDGVKIISVGVQKASEENLKAMATSQFHFNLRTVRDLSMFSQNMTHIIKDV 206 Query: 817 TTYVSGGVEE--VPLAQPESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGT 873 Y G V++ V Q S D++FL D S N + F ++ FL + + L++K Sbjct: 207 IKYKEGAVDDIFVEACQGPSMADVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCM 266 Query: 874 RIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAG 933 R+ + YS++ KV + +K E+L ++ + +TGKA G A+ ++ +F G Sbjct: 267 RVGLVAYSNETKVINSLSMGINKSEVLQHIQNLSPRTGKAYT-GAAIKKLRKEVFSARNG 325 Query: 934 SRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFI 993 SR GV Q VL+ S D V A NL++ GV F + A +LE+I PA Sbjct: 326 SRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAEQ 385 Query: 994 LAAESLPKIGDLHPQIVNLLKSVHNGAPAPVS----------------GEKDVVFLLDGS 1037 ++ L DL LK + N VS E D+ L+DGS Sbjct: 386 YVSK-LKTFADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSGCVDTEEADIYLLIDGS 444 Query: 1038 EGVRS-GFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVR 1096 ++ F +K F+ VV ++ +VRV VQY+D EF +N Y NKQD+ A+ Sbjct: 445 GSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEINKYSNKQDLGKAIE 504 Query: 1097 QLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVK 1156 + +GG T NTGAAL F L L+ A + VP L+VLT S D + P+ ++ Sbjct: 505 NIRQMGGNT-NTGAALNFTLS--LLQKAKKQRGNKVPCHLVVLTNGMSKDSILEPANRLR 561 Query: 1157 RGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQ-QVISERVTQLTREELSR 1215 IGI A+ T+++ I+ + F L ++ QV+ E T+ +E+ Sbjct: 562 EEHIRVYAIGIKEANQTQLREIAGEEKRVYYVHDFDALKDIRNQVVQEICTEEACKEM-- 619 Query: 1216 LQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVI 1274 K D++FL+D S S GPE F ++T ++ LV +G D ++ V+ Sbjct: 620 ---------------KADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVV 664 Query: 1275 QFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE 1334 QFSD K EF LN S+ ++ NA+ ++ G + G+AL +VS+ F G+R Sbjct: 665 QFSDINKEEFQLNRFMSQSDISNAIDQMAHIGQTTLT-GSALSFVSQ-YFSPTKGAR--P 720 Query: 1335 GVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIAR-NADQEELVKISLSPEYVFSVST 1393 + +FL+LI+ G++ D V +PAV L+Q GV +++ ++ +L +IS PE VF V Sbjct: 721 NIRKFLILITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVEN 780 Query: 1394 FRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFA 1453 F L +E L+ I + E+ +++ + D+VF+IDSS + D + Sbjct: 781 FDILQRIEDDLVFGICS-PREECKRI-------------EVLDVVFVIDSSGSIDYDEYN 826 Query: 1454 HIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSP 1513 ++DF+ +V++ ++G ++VR G +++++D FYL + ++ V+ ++ + GGS Sbjct: 827 IMKDFMIGLVKKADVGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGST 886 Query: 1514 LNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQD--DVSRFAQVIRSSGIVSL 1571 T +AL F + ++F ++ GSR+ GVPQ L+++ G+S D ++ A+ +R GI+ L Sbjct: 887 Y-TAEALGF-SDHMFTEARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVL 944 Query: 1572 GVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPS 1631 VG + EL + F V F L I + S S+ Sbjct: 945 AVGIDGANPVELLAMAGSSDKYFFVETFGGLKGIFSDVTASVCNSSKVDC---------- 994 Query: 1632 RPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEF 1691 E K D+VFL+DGS + + + F+++ F++ +V + +++G Q++ EF Sbjct: 995 --EIDKVDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEF 1052 Query: 1692 FLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNH-FVPEAGSRLDQRVPQIAFVI 1750 L F +++I I + G NT +G V H F P+ GSR++ PQ+ V+ Sbjct: 1053 PLGTFIGEKEISFQIENIKQIFG---NTHIGAALREVEHYFRPDMGSRINTGTPQVLLVL 1109 Query: 1751 TGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSE 1810 T G+S ++ + AL RG+ +++VG+ ++D +++ +I + V N EL ++++ Sbjct: 1110 TDGQSQDEVAQAAEALRHRGIDIYSVGIGDVDDQQLIQITGTAEKKLTVHNFDELKKVNK 1169 Query: 1811 QVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGS---RDQNVFVAQKGFESKVDAILN 1867 +++ + C T C +DV++GFD S + Q + Q E+ + IL Sbjct: 1170 RIVRNI--------C--TTAGESNCFVDVVVGFDVSTQEKGQTLLEGQPWMETYLQDILR 1219 Query: 1868 RISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFD--FDEYQPEMLEKFRNMRSQHPYVL 1925 IS ++ VSC G V V+ + +E + F+ Y +L +++ + P +L Sbjct: 1220 AISSLNGVSCEVGTETQVSVAFQV---TNAMEKYSPKFEIYSENILNSLKDITVKGPSLL 1276 Query: 1926 TEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILVGLERV 1985 + L + F+ S KVV+ F+DG D D+ L + S+ LR+EG+ ALI V L+ Sbjct: 1277 NANLLDSLWDTFQNKSAARGKVVLLFSDGLDDDVEKLEQKSDELRKEGLNALITVALDGP 1336 Query: 1986 VN---LERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQRGD 2042 + L L ++EFG+GF Y L + + +L L++QL N+AE+ CC + CKC G G Sbjct: 1337 ADSSDLADLPYIEFGKGFEYRTQLSIGMRELGSRLSKQLVNVAERTCCCLFCKCIGGDGT 1396 Query: 2043 RGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGE 2102 G G G +G PG G GY G+EG GERG PG G QG +GC G +G KG+RG G+ Sbjct: 1397 MGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNRGLNGQ 1456 Query: 2103 KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQ 2162 +GEVGE G+DGL+GE GD GLPG GEKG+ G +G G RG G+RG G+RGDPG PG Sbjct: 1457 EGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDPGAPGV 1516 Query: 2163 DSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEG 2222 DS GP G G+ G G G G PG PG K GRRG G +G G PG G EG Sbjct: 1517 DSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEG 1576 Query: 2223 EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKG 2282 G +G QGP G AG G G G GP+G G G G +GR G G KGEPG+ G KG Sbjct: 1577 SLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKG 1636 Query: 2283 GIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGR 2342 +G GPRG G+DG G GS GR+G KG+ GFPG GPKG G+PG G TG KG RG+ Sbjct: 1637 AVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGK 1696 Query: 2343 RGNSGPPGIVGQKGDPGYPGPAGPKGNRG-DSIDQCALIQSIKDKCPCCYGPLECPVFPT 2401 ++G PG +G G+PG PG G KG +G S C LIQ ++D+ P +G ECPV PT Sbjct: 1697 MISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKPECPVHPT 1756 Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 2461 EL FALD S V + F RM++++ +V D+ + E++CP GA +A+++YN+ +RF+ Sbjct: 1757 ELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYNSHARHLVRFS 1816 Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTR 2521 D+ +KS LL +I+ + +S + + AM F++RN FKR G RK+A FFS+ + Sbjct: 1817 DAYKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKRTLPGAHTRKIATFFSSGQSA 1876 Query: 2522 ASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLENV 2581 + + A ++ I P+ +T + A I++T +V+P+G D LE + Sbjct: 1877 DAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAIDDTGTFQVIVVPSGADYIPALERL 1936 Query: 2582 LTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKY 2641 C C D+C D SC R +D AF+LD++ +F +++ + Sbjct: 1937 QRCTFCYDVCKPDASCD---------QARPPPVQSYMDAAFLLDASRNMGSAEFEDIRAF 1987 Query: 2642 IAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDF 2701 + L+ +++P+P+ S RVA++ HAP + + N PV+ EF+LT Y SK + Sbjct: 1988 LGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEFNLTTYRSKRLMKRH 2047 Query: 2702 LSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQ 2761 + + QL G +G A+++T++NVF S PN R K++ ++ GE E ++ L+ Sbjct: 2048 VHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRNKVIFVISAGETSHLDGEILKKESLR 2107 Query: 2762 AKCKGYFFVVLGIGRKVNIKEVYTFASEPND 2792 AKC+GY V +G + KE+ AS P D Sbjct: 2108 AKCQGYALFVFSLGPIWDDKELEDLASHPLD 2138 Score = 478 bits (1230), Expect = e-134 Identities = 338/1185 (28%), Positives = 613/1185 (51%), Gaps = 52/1185 (4%) Query: 38 ADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYR 97 AD++FLVDSS +G + F V+ F+ ++ SL + + + AL Q++ H+EF L+T++ Sbjct: 26 ADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFK 85 Query: 98 TKQEVLSHI-SNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKD 156 + +L+H+ N +IGG+ Q GK L+ +++ + A R P ++VVL S+D Sbjct: 86 GRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVLASSESED 145 Query: 157 GLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSC 216 + S L+ V + ++GV+ A E LK +A+ + FNL L N+ Sbjct: 146 NVEEASKALRKDGVKIISVGVQKASEENLKAMATSQFH---FNLRTVRDLSMFSQNMTHI 202 Query: 217 VHSSVS-PERAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIG 275 + + E A D ++ AD++FL+D S N NF + FL + L I Sbjct: 203 IKDVIKYKEGAVDDIFVEACQGPSMADVVFLLDMSINGSEENFDYLKGFLEESVSALDIK 262 Query: 276 TQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFT 335 +RVG+V +S+E + + SL K++VL ++ L G+ A G A+ + + F+ Sbjct: 263 ENCMRVGLVAYSNETKVINSLSMGINKSEVLQHIQNLSPRTGK-AYTGAAIKKLRKEVFS 321 Query: 336 RAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATD 395 GSR +GVPQ+ VL++ S D + V L++ V F LG + AS +L+ IA+ Sbjct: 322 ARNGSRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASH 381 Query: 396 DNLVFTVPEFRSFGDLQEKLLPYIVGVAQR--HIVL----KPPTIVTQVIEVNKRDIVFL 449 + V + ++F DL ++ + + H V + T+ + ++ + DI L Sbjct: 382 PAEQY-VSKLKTFADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSGCVDTEEADIYLL 440 Query: 450 VDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVI 509 +DGS + +F+ ++ F+++V+ I ++V QYAD+ EF N + K+++ Sbjct: 441 IDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEINKYSNKQDLG 500 Query: 510 TAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPA 569 A+ ++ + G+ TG+AL+F + L A + +P LV++T G S D I +PA Sbjct: 501 KAIENIRQMGGNT-NTGAALNFTLSLL--QKAKKQRGNKVPCHLVVLTNGMSKDSILEPA 557 Query: 570 QELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSG 629 L+ I +AIG K A+Q +L EIA + V+ +F A L+ + ++ + T Sbjct: 558 NRLREEHIRVYAIGIKEANQTQLREIAGEEKRVYYVHDFDA--LKDIRNQVVQEICTEEA 615 Query: 630 TPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVT 689 E+ K DI+FL+D S ++G NF ++ F+ NLV+ IG D +++G+VQFSD Sbjct: 616 CKEM---KADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINKE 672 Query: 690 EFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLL 749 EF LN + ++SDI + Q+ G + L TGSALS+V + +F+ G+ R ++ + L+L Sbjct: 673 EFQLNRFMSQSDISNAIDQMAHIGQTTL-TGSALSFV-SQYFSPTKGA--RPNIRKFLIL 728 Query: 750 LTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALP 809 +T G+++D + A L + G++ + VG +N +LE+I+ P +V+ +++F L + Sbjct: 729 ITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVENFDILQRIE 788 Query: 810 QQLIQPLTTYVSGGVEEVPLAQPESKR----DILFLFDGSANL-VGQFPVVRDFLYKIID 864 L+ + + + E KR D++F+ D S ++ ++ +++DF+ ++ Sbjct: 789 DDLVFGICS-----------PREECKRIEVLDVVFVIDSSGSIDYDEYNIMKDFMIGLVK 837 Query: 865 ELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQ 924 + +V R +Y+DD +V D+ +K E++++++ + G AL ++ Sbjct: 838 KADVGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGSTYT-AEALGFSD 896 Query: 925 RYIFVKSAGSRIEDGVLQFLVLLVAGRS--SDRVDGPASNLKQSGVVPFIFQAKNADPAE 982 ++F ++ GSR+ GV Q L+++ G S +D+++ A L+ G++ A+P E Sbjct: 897 -HMFTEARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVE 955 Query: 983 LEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEK-DVVFLLDGSEGVR 1041 L + S E+ G L ++ SV N + +K D+VFL+DGS ++ Sbjct: 956 LLAMAGSSDKYFFVET---FGGLKGIFSDVTASVCNSSKVDCEIDKVDLVFLMDGSTSIQ 1012 Query: 1042 -SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTL 1100 + F +KEF+ VV+ DV +RVR+ Q+SD PEF L +++ ++++ + + Sbjct: 1013 PNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIGEKEISFQIENIKQ 1072 Query: 1101 LGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGA 1160 + G T + GAAL V + GSRI G PQ+L+VLT +S D+V + ++ G Sbjct: 1073 IFGNT-HIGAALREV-EHYFRPDMGSRINTGTPQVLLVLTDGQSQDEVAQAAEALRHRGI 1130 Query: 1161 VPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERV 1205 +GIG+ D ++ I+ + + + F +L V + I + Sbjct: 1131 DIYSVGIGDVDDQQLIQITGTAEKKLTVHNFDELKKVNKRIVRNI 1175 Score = 382 bits (980), Expect = e-105 Identities = 299/1096 (27%), Positives = 533/1096 (48%), Gaps = 82/1096 (7%) Query: 38 ADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYR 97 AD++FL+D S EE+F ++ FL + V +L + EN LV ++ L+ Sbjct: 228 ADVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGI 287 Query: 98 TKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDG 157 K EVL HI N+S G TG ++ + + + GSR GVPQ+ V++T S+D Sbjct: 288 NKSEVLQHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSRKNQGVPQIAVLVTHRDSEDN 347 Query: 158 LALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENF--------TSLHDI 209 + + L+ V +F +G+E A + L++IAS P ++ L+ F T L + Sbjct: 348 VTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAEQYVSKLKTFADLAAHNQTFLKKL 407 Query: 210 VGNLVSCVHSSVSPERAGDTETLKD-ITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNL 268 + V SV ER TETLK + ADI LIDGS +T + +F + FL + Sbjct: 408 RNQITHTV--SVFSER---TETLKSGCVDTEEADIYLLIDGSGSTQATDFHEMKTFLSEV 462 Query: 269 LEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDF 328 + I ++RVG VQ++D F ++ YS K + A++ + GG N G AL+F Sbjct: 463 VGMFNIAPHKVRVGAVQYADSWDLEFEINKYSNKQDLGKAIENIRQMGGN-TNTGAALNF 521 Query: 329 VVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAE 388 + + + VP LV+++ G S D I L++ + + +G + A++ + Sbjct: 522 TLS--LLQKAKKQRGNKVPCHLVVLTNGMSKDSILEPANRLREEHIRVYAIGIKEANQTQ 579 Query: 389 LQHIATDDNLVFTVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVF 448 L+ IA ++ V+ V +F + D++ +++ I + + K DI+F Sbjct: 580 LREIAGEEKRVYYVHDFDALKDIRNQVVQEI--------------CTEEACKEMKADIMF 625 Query: 449 LVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREV 508 LVD S ++G NF+ ++ F+ ++ + +IG D +Q+ V Q++D + EF N ++ ++ Sbjct: 626 LVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINKEEFQLNRFMSQSDI 685 Query: 509 ITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQP 568 A+ +M + G TGSAL FV + F+ + G A I K L+LIT G++ D + +P Sbjct: 686 SNAIDQMAHI-GQTTLTGSALSFV-SQYFSPTKG--ARPNIRKFLILITDGEAQDIVKEP 741 Query: 569 AQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPL--QGMLPGLLAPLRT 626 A L++ ++ +++G G++ +LEEI+ +VF F ++ G+ +P Sbjct: 742 AVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVENFDILQRIEDDLVFGICSPREE 801 Query: 627 LSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDT 686 + D++F++D S ++ + ++DF++ LV D+G + +R G ++++D Sbjct: 802 CKRIEVL-----DVVFVIDSSGSIDYDEYNIMKDFMIGLVKKADVGKNQVRFGALKYADD 856 Query: 687 PVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANH-FTEAGGSRIREHVPQ 745 P F L+ + TK +++ L+ Q GGS T +A + +++H FTEA GSR+ + VPQ Sbjct: 857 PEVLFYLDDFGTKLEVISVLQNDQAMGGS---TYTAEALGFSDHMFTEARGSRLNKGVPQ 913 Query: 746 LLLLLTAGQSEDS--YLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFS 803 +L+++T G+S D+ A AL GIL VG AN EL +A + + ++ F Sbjct: 914 VLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVELLAMAGSSDKYFFVETFG 973 Query: 804 SLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANL-VGQFPVVRDFLYKI 862 L + + + E K D++FL DGS ++ F +++FL + Sbjct: 974 GLKGIFSDVTASVCNSSKVDCE-------IDKVDLVFLMDGSTSIQPNDFKKMKEFLASV 1026 Query: 863 IDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDY 922 + + +V RI AQ+SD E + EI ++ +K G ++G AL Sbjct: 1027 VQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIGEKEISFQIENIKQIFGNT-HIGAALRE 1085 Query: 923 AQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAE 982 + Y F GSRI G Q L++L G+S D V A L+ G+ + + D + Sbjct: 1086 VEHY-FRPDMGSRINTGTPQVLLVLTDGQSQDEVAQAAEALRHRGIDIYSVGIGDVDDQQ 1144 Query: 983 LEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGS----- 1037 L QI + L + ++ ++ +IV + + + V DVV D S Sbjct: 1145 LIQITGTAEKKLTVHNFDELKKVNKRIVRNICTTAGESNCFV----DVVVGFDVSTQEKG 1200 Query: 1038 EGVRSGFPLLKEFVQRVVE--------SLDVG---QDRVRVAVVQYSDRTRPEFYLNSYM 1086 + + G P ++ ++Q ++ S +VG Q V V ++ P+F + S Sbjct: 1201 QTLLEGQPWMETYLQDILRAISSLNGVSCEVGTETQVSVAFQVTNAMEKYSPKFEIYS-- 1258 Query: 1087 NKQDVVNAVRQLTLLG 1102 ++++N+++ +T+ G Sbjct: 1259 --ENILNSLKDITVKG 1272 Score = 154 bits (390), Expect = 1e-36 Identities = 141/559 (25%), Positives = 251/559 (44%), Gaps = 36/559 (6%) Query: 1435 ADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYR 1494 AD+VFL+DSS+ + F ++ F+++++ L I K RV + Q+S+ + EF+L T++ Sbjct: 26 ADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFK 85 Query: 1495 SQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQD 1554 ++P+L+ +R+ G L GKAL+ R F A R + P LV++ +S+D Sbjct: 86 GRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVLASSESED 145 Query: 1555 DVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFG 1614 +V ++ +R G+ + VG + L+ + + F +R R+L + + + Sbjct: 146 NVEEASKALRKDGVKIISVGVQKASEENLKAMATS-QFHFNLRTVRDLSMFSQNMTHIIK 204 Query: 1615 PSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGD 1674 D + AD+VFLLD SIN ++F + F+ E V + + Sbjct: 205 DVIKYKEGAVDDIFVEACQGPSMADVVFLLDMSINGSEENFDYLKGFLEESVSALDIKEN 264 Query: 1675 SIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPE 1734 ++VGLV Y+++ L K +++ I + + G+ A T ++ LR F Sbjct: 265 CMRVGLVAYSNETKVINSLSMGINKSEVLQHIQNLSPRTGK-AYTGAAIKKLRKEVFSAR 323 Query: 1735 AGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSA 1794 GSR +Q VPQIA ++T S ++ ++ L + GV +F +G+ ++ KIAS+ A Sbjct: 324 NGSRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPA 383 Query: 1795 TAF----------RVGNVQELSELSEQVLET--LHDAMHETLCPGVTDAAKACNLDVILG 1842 + N L +L Q+ T + ETL G D +A ++ +++ Sbjct: 384 EQYVSKLKTFADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSGCVDTEEA-DIYLLID 442 Query: 1843 FDGSRDQNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFD 1902 GS F K F S+V + N VRV V S +E F+ Sbjct: 443 GSGSTQATDFHEMKTFLSEVVGMFNIAPH------------KVRVGAVQYADSWDLE-FE 489 Query: 1903 FDEY--QPEMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPD-SVKVVIH---FTDGAD 1956 ++Y + ++ + N+R T L L+ +++ KV H T+G Sbjct: 490 INKYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSLLQKAKKQRGNKVPCHLVVLTNGMS 549 Query: 1957 GDLADLHRASENLRQEGVR 1975 D + + LR+E +R Sbjct: 550 KD--SILEPANRLREEHIR 566 Score = 52.4 bits (124), Expect = 7e-06 Identities = 78/362 (21%), Positives = 140/362 (38%), Gaps = 65/362 (17%) Query: 39 DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDF----HFALVQFNGNPHTEFLLN 94 +++F +D S + E+ F+ ++E + +V+ + V EN H A++ +N + + Sbjct: 1757 ELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYNSHARHLVRFS 1816 Query: 95 TYRTKQEVLSHISNMSY--IGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDG 152 K ++L I + Y + + G+ + +I ++ + G ++ + G Sbjct: 1817 DAYKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKRTL---PGAHTRKIATFFSSG 1873 Query: 153 HSKDGLALPSAELKSADVNVFAIGVEDA------------DEGALKEI---ASEPLNMHM 197 S D ++ +A ++ + + + + + D G + I + + Sbjct: 1874 QSADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAIDDTGTFQVIVVPSGADYIPAL 1933 Query: 198 FNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVN 257 L+ T +D+ SC + P Q D FL+D S N GS Sbjct: 1934 ERLQRCTFCYDVCKPDASCDQARPPP-------------VQSYMDAAFLLDASRNMGSAE 1980 Query: 258 FAVILDFLVNLLEKLPI----GTQQIRVGVVQFSDEP------------RTMFSLDTYST 301 F I FL LL+ I T V S P R F+L TY + Sbjct: 1981 FEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEFNLTTYRS 2040 Query: 302 ----KAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGP 357 K V +VK L G+ A IG AL + ++N F R +V+ +ISAG Sbjct: 2041 KRLMKRHVHESVKQL---NGD-AFIGHALQWTLDNVFLSTPNLRRN----KVIFVISAGE 2092 Query: 358 SS 359 +S Sbjct: 2093 TS 2094 Score = 49.3 bits (116), Expect = 6e-05 Identities = 84/412 (20%), Positives = 160/412 (38%), Gaps = 72/412 (17%) Query: 629 GTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVG--------- 679 G PE + +++F LD S +V + F +++ + LV + + ++ VG Sbjct: 1747 GKPECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYN 1806 Query: 680 -----LVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGS-GLNTGSALSYVYANHFTE 733 LV+FSD KS +L + + + S G A+ ++ N F Sbjct: 1807 SHARHLVRFSDA----------YKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKR 1856 Query: 734 AGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQ-IAFN 792 + H ++ ++GQS D++ A+ + V + +N + + A + Sbjct: 1857 ---TLPGAHTRKIATFFSSGQSADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAID 1913 Query: 793 PS----LVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQP---ESKRDILFLFDGS 845 + ++ + +PAL + V A+P +S D FL D S Sbjct: 1914 DTGTFQVIVVPSGADYIPALERLQRCTFCYDVCKPDASCDQARPPPVQSYMDAAFLLDAS 1973 Query: 846 ANL-VGQFPVVRDFLYKIIDELNVKPE------GTRIAVAQYS----------DDVKVES 888 N+ +F +R FL ++D + PE G R+A+ ++ V+ E Sbjct: 1974 RNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEF 2033 Query: 889 RFDEHQSKPEILNLVKRMKIKTGKALN----LGYALDYAQRYIFVKSAGSRIEDGVLQFL 944 ++SK L+KR ++ K LN +G+AL + +F+ + R + Sbjct: 2034 NLTTYRSK----RLMKRHVHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRNK-----V 2084 Query: 945 VLLVAGRSSDRVDG-----PASNLKQSGVVPFIFQAKNA-DPAELEQIVLSP 990 + +++ + +DG + K G F+F D ELE + P Sbjct: 2085 IFVISAGETSHLDGEILKKESLRAKCQGYALFVFSLGPIWDDKELEDLASHP 2136 >gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens] Length = 2526 Score = 1032 bits (2668), Expect = 0.0 Identities = 706/2188 (32%), Positives = 1101/2188 (50%), Gaps = 127/2188 (5%) Query: 639 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQT 698 D++FL+D S ++G +FP+V+ F+ ++NSL I + RV L Q+SD +EF L+T++ Sbjct: 30 DVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHSEFHLSTFKG 89 Query: 699 KSDILGHLRQ-LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSED 757 +S +L HL++ Q GGS L G AL + +F+ R R+ P +L++L + +SED Sbjct: 90 RSPMLNHLKKNFQFIGGS-LQIGKALQEAHRTYFSAPINGRDRKQFPPILVVLASAESED 148 Query: 758 SYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYL--MDDFSSLPALPQQLIQP 815 +A+ AL + G+ VG +A++ L+ +A + L + D S+ Q+I+ Sbjct: 149 EVEEASKALQKDGVKIISVGVQKASEENLKAMATSHFHFNLRTIRDLSTFSQNMTQIIKD 208 Query: 816 LTTYVSGGVE-----EVPLA-QPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVK 869 +T Y G V+ P++ Q +S D++FL D S G ++ FL I ++VK Sbjct: 209 VTKYKEGAVDADMQVHFPISCQKDSLADLVFLVDESLGTGGNLRHLQTFLENITSSMDVK 268 Query: 870 PEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFV 929 R+ + YS+ K S ++ E +K + I+ GK+ N G A+D +R F Sbjct: 269 ENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQIKNLSIQVGKS-NTGAAIDQMRRDGFS 327 Query: 930 KSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLS 989 +S GSR GV Q VL+ S D V A NL+ V F + A+ +LE+IV Sbjct: 328 ESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNLRLEDVNVFALSIQGANNTQLEEIVSY 387 Query: 990 PAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSG----------------EKDVVFL 1033 P +L DL LK + N + +S E D+ FL Sbjct: 388 PPE-QTISTLKSYADLETYSTKFLKKLQNEIWSQISTYAEQRNLDKTGCVDTKEADIHFL 446 Query: 1034 LDGSEGVRSG-FPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVV 1092 +DGS ++ F +K F+ V E +G D+VRV VVQYSD T EFY+ Y N D+ Sbjct: 447 IDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFYITDYSNDIDLR 506 Query: 1093 NAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPS 1152 A+ + L G T TG AL+++L+ I+ + R+++ VP LIVLT S D V P+ Sbjct: 507 KAIFNIKQLTGGT-YTGKALDYILQ-IIKNGMKDRMSK-VPCYLIVLTDGMSTDRVVEPA 563 Query: 1153 VVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQ-QVISERVTQLTRE 1211 ++ +GIG A+ E+Q I+ + F L +++ +V+ E + E Sbjct: 564 KRLRAEQITVHAVGIGAANKIELQEIAGKEERVSFGQNFDALKSIKNEVVREICAEKGCE 623 Query: 1212 ELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTR 1270 ++ K D++FL+D S S G E F+ ++ ++ L+ + +G D T+ Sbjct: 624 DM-----------------KADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGADKTQ 666 Query: 1271 VAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGS 1330 + V+QFSD K EF LN + ++ E+ +A+ R+ + G AL +V + F G+ Sbjct: 667 IGVVQFSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTLT-GKALNFVGQ-YFTHSKGA 724 Query: 1331 RIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIA-RNADQEELVKISLSPEYVF 1389 R+ G +FL+LI+ G + D+V DPA L+ V F++ NA++ +L +IS VF Sbjct: 725 RL--GAKKFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGDSSLVF 782 Query: 1390 SVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRP 1449 V F L +LE+KL+ + L + LL D+VF++D S ++ Sbjct: 783 HVENFDHLKALERKLIFRVCALHDCKRITLL---------------DVVFVLDHSGSIKK 827 Query: 1450 DGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLR 1509 H+ + +V++ ++G +V+ G +++S+ FYL TY +++ +++ +R+ R Sbjct: 828 QYQDHMINLTIHLVKKADVGRDRVQFGALKYSDQPNILFYLNTYSNRSAIIENLRKRRDT 887 Query: 1510 GGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQD--DVSRFAQVIRSSG 1567 GG+ T KAL+ A LF + GSRI+ V Q L+++ G+S D ++ A +R+ G Sbjct: 888 GGNTY-TAKALKH-ANALFTEEHGSRIKQNVKQMLIVITDGESHDHDQLNDTALELRNKG 945 Query: 1568 IVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDT 1627 I VG ++ EL+ + + V F +L ++ + + T Sbjct: 946 ITIFAVGVGKANQKELEGMAGNKNNTIYVDNFDKLKDVFTLVQER------------MCT 993 Query: 1628 PPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDP 1687 P ++AD++FL DGS F + F+S+++D +++G+ Q+ S+ Sbjct: 994 EAPEVCHLQEADVIFLCDGSDRVSNSDFVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSNY 1053 Query: 1688 TDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIA 1747 LK+ TK Q I V GG L+ + N F AG R + VPQ Sbjct: 1054 QSIIELKNSLTKTQWKTQIQNVSKSGG-FPRIDFALKKVS-NMFNLHAGGRRNAGVPQTL 1111 Query: 1748 FVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELS- 1806 VIT G D D L G+ V +G+ ++ E + I NS + +L Sbjct: 1112 VVITSGDPRYDVADAVKTLKDLGICVLVLGIGDVYKEHLLPITGNSEKIITFQDFDKLKN 1171 Query: 1807 -ELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGS---RDQNVFVAQKGFESKV 1862 ++ ++++ + + +T C +D+++GFD S + Q +F ES + Sbjct: 1172 VDVKKRIIREICQSCGKT----------NCFMDIVVGFDISTHVQGQPLFQGHPQLESYL 1221 Query: 1863 DAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQHP 1922 IL IS + VSC G V ++ N+ G F YQ + + + P Sbjct: 1222 PGILEDISSIKGVSCGAGTEAQVSLAFKVNSDQGFPAKFQI--YQKAVFDSLLQVNVSGP 1279 Query: 1923 YVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDL-ADLHRASENLRQEGVRALILVG 1981 L L+ + F+ S +V++ F+DG + L S+ LR+ G+ AL++V Sbjct: 1280 THLNAQFLRSLWDTFKDKSASRGQVLLIFSDGLQSESNIMLENQSDRLREAGLDALLVVS 1339 Query: 1982 LERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQRG 2041 L + E EFG+ F Y L + + +L +L++ L NIAE+ CC CKC G G Sbjct: 1340 LNTTAHHE-FSSFEFGKRFDYRTHLTIGMRELGKKLSQYLGNIAERTCCCTFCKCPGIPG 1398 Query: 2042 DRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPG 2101 G G KG G G RG+ G++G PG RG G G +G GCPG G KG +GF G Sbjct: 1399 PHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFSG 1458 Query: 2102 EKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPG 2161 KG G+ G+DGLDGE+G G PG GEKG+PG +G G RG G+ G+ G GDPGNPG Sbjct: 1459 PKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPG 1518 Query: 2162 QDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFE 2221 Q++ +G KG G+ G G G+ GV G P G G G+RG G G G PG G Sbjct: 1519 QNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGTL 1578 Query: 2222 GEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPK 2281 G +G +G QG G G G G QG GP+GS G GA G GR G LG+KGEPG PG Sbjct: 1579 GAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDL 1638 Query: 2282 GGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRG 2341 G +G G RG GD G G G GR+G KG RGFPG G KG+ G PG+ G GPKG RG Sbjct: 1639 GPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRG 1698 Query: 2342 RRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSI-DQCALIQSIKDKCPCCYGPLECPVFP 2400 G G G +G PG PG G KG G + QC LI+ +++ PC +CP +P Sbjct: 1699 LALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCDLIRFLREHSPC--WKEKCPAYP 1756 Query: 2401 TELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRF 2460 TEL FALD S V +++F + RD++ SIVNDL I E+NCP GARVA+V+YN+ + IR+ Sbjct: 1757 TELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNSGTSYLIRW 1816 Query: 2461 ADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPT 2520 +D RK LL ++ ++ T++ + + AM FV RN FKR G +R+VAVFFSN T Sbjct: 1817 SDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYAGANVRRVAVFFSNGQT 1876 Query: 2521 RASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLEN 2580 + + A ++ S I+P E R + A +NT + +P + LE Sbjct: 1877 ASRSSIITATMEFSALDISPTVFAFDE-RVFLEAFGFDNTGTFQVIPVPPNGE-NQTLER 1934 Query: 2581 VLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKK 2640 + C +C D C +C ++ P D +D+ F++D++ +F +K Sbjct: 1935 LRRCALCYDKC-FPNACIREAFLP---------EDSYMDVVFLIDNSRNIAKDEFKAVKA 1984 Query: 2641 YIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVD 2700 ++ ++ +++ DP S R+A++ ++P ES M VK EF Y ++ + + Sbjct: 1985 LVSSVIDNFNIASDPLISDSGDRIALLSYSPWES-SRRKMGTVKTEFDFITYDNQLLMKN 2043 Query: 2701 FLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVIL 2760 + QL G +G A+ +T EN+F P R K++ ++ GE E++ E + + L Sbjct: 2044 HIQTSFQQLNGEATIGRALLWTTENLFPETPYLRKHKVIFVVSAGENYERK-EFVKMMAL 2102 Query: 2761 QAKCKGY--FFVVLGIGRKVNIKEVYTF 2786 +AKC+GY F + LG RK +++E+ ++ Sbjct: 2103 RAKCQGYVIFVISLGSTRKDDMEELASY 2130 Score = 416 bits (1070), Expect = e-115 Identities = 316/1152 (27%), Positives = 574/1152 (49%), Gaps = 56/1152 (4%) Query: 38 ADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYR 97 AD++FLVDSS +G + F V+ F+ ++ SL + N + AL Q++ H+EF L+T++ Sbjct: 29 ADVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHSEFHLSTFK 88 Query: 98 TKQEVLSHI-SNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKD 156 + +L+H+ N +IGG+ Q GK L+ +++ + R P ++VVL S+D Sbjct: 89 GRSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRKQFPPILVVLASAESED 148 Query: 157 GLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSC 216 + S L+ V + ++GV+ A E LK +A+ + ++ + + ++ + ++ Sbjct: 149 EVEEASKALQKDGVKIISVGVQKASEENLKAMATSHFHFNLRTIRDLSTFSQNMTQIIKD 208 Query: 217 VHSSVSPERAGDTETLKDITAQDS--ADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPI 274 V D + I+ Q AD++FL+D S TG N + FL N+ + + Sbjct: 209 VTKYKEGAVDADMQVHFPISCQKDSLADLVFLVDESLGTGG-NLRHLQTFLENITSSMDV 267 Query: 275 GTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHF 334 +R+G++ +S+ +T+ L + +T+++ +K L G+ +N G A+D + + F Sbjct: 268 KENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQIKNLSIQVGK-SNTGAAIDQMRRDGF 326 Query: 335 TRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIAT 394 + + GSR +GVPQ+ VL++ PS DE+ + L+ V F L Q A+ +L+ I + Sbjct: 327 SESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNLRLEDVNVFALSIQGANNTQLEEIVS 386 Query: 395 DDNLVFTVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIVTQ-------VIEVNKRDIV 447 T+ +S+ DL+ ++ + Q I + T Q ++ + DI Sbjct: 387 YPP-EQTISTLKSYADLETYSTKFLKKL-QNEIWSQISTYAEQRNLDKTGCVDTKEADIH 444 Query: 448 FLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKRE 507 FL+DGSS++ F I+ F+ +V + IG D ++V V QY+D EFY + + Sbjct: 445 FLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFYITDYSNDID 504 Query: 508 VITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQ 567 + A+ +K L G YTG ALD++ + + R ++ +P L+++T G S D + + Sbjct: 505 LRKAIFNIKQLTGGT-YTGKALDYIL-QIIKNGMKDRMSK-VPCYLIVLTDGMSTDRVVE 561 Query: 568 PAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTL 627 PA+ L+ I A+G A++ EL+EIA V F A L+ + ++ + Sbjct: 562 PAKRLRAEQITVHAVGIGAANKIELQEIAGKEERVSFGQNFDA--LKSIKNEVVREICAE 619 Query: 628 SGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTP 687 G ++ K DI+FL+D S ++G NF ++ F+ NL+ + IG D ++G+VQFSD Sbjct: 620 KGCEDM---KADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGADKTQIGVVQFSDKT 676 Query: 688 VTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLL 747 EF LN Y T+ +I + ++ L G TG AL++V +FT + G+R+ + L Sbjct: 677 KEEFQLNRYFTQQEISDAIDRMSLI-NEGTLTGKALNFV-GQYFTHSKGARL--GAKKFL 732 Query: 748 LLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPA 807 +L+T G ++D A L + F VG AN+++LE+I+ + SLV+ +++F L A Sbjct: 733 ILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGDSSLVFHVENFDHLKA 792 Query: 808 LPQQLIQPLTTYVSGGVEEVPLAQPESKR----DILFLFDGSANLVGQF-PVVRDFLYKI 862 L ++LI + A + KR D++F+ D S ++ Q+ + + + Sbjct: 793 LERKLIFRV------------CALHDCKRITLLDVVFVLDHSGSIKKQYQDHMINLTIHL 840 Query: 863 IDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEIL-NLVKRMKIKTGKALNLGYALD 921 + + +V + + +YSD + + + ++ I+ NL KR TG AL Sbjct: 841 VKKADVGRDRVQFGALKYSDQPNILFYLNTYSNRSAIIENLRKRR--DTGGNTYTAKALK 898 Query: 922 YAQRYIFVKSAGSRIEDGVLQFLVLLVAGRS--SDRVDGPASNLKQSGVVPFIFQAKNAD 979 +A +F + GSRI+ V Q L+++ G S D+++ A L+ G+ F A+ Sbjct: 899 HANA-LFTEEHGSRIKQNVKQMLIVITDGESHDHDQLNDTALELRNKGITIFAVGVGKAN 957 Query: 980 PAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVS-GEKDVVFLLDGSE 1038 ELE + + + ++ K+ D+ + + + AP E DV+FL DGS+ Sbjct: 958 QKELEGMAGNKNNTIYVDNFDKLKDVFTLV---QERMCTEAPEVCHLQEADVIFLCDGSD 1014 Query: 1039 GV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQ 1097 V S F + F+ ++++ D+ R+++ + Q+ + L + + K ++ Sbjct: 1015 RVSNSDFVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSNYQSIIELKNSLTKTQWKTQIQN 1074 Query: 1098 LTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKR 1157 ++ GG P AL+ V N+ AG R GVPQ L+V+T+ DV + +K Sbjct: 1075 VSKSGG-FPRIDFALKKV-SNMFNLHAGGRRNAGVPQTLVVITSGDPRYDVADAVKTLKD 1132 Query: 1158 GGAVPIGIGIGN 1169 G + +GIG+ Sbjct: 1133 LGICVLVLGIGD 1144 Score = 299 bits (766), Expect = 3e-80 Identities = 273/1049 (26%), Positives = 483/1049 (46%), Gaps = 90/1049 (8%) Query: 1020 APAPVSGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRP 1078 +P P DVVFL+D S+ + FP +K F+ +++ SL + ++ RVA+ QYSD Sbjct: 21 SPGPGPVYADVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHS 80 Query: 1079 EFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIV 1138 EF+L+++ + ++N +++ G + G AL+ R + R + P +L+V Sbjct: 81 EFHLSTFKGRSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRKQFPPILVV 140 Query: 1139 LTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQ 1198 L + S D+V S +++ G I +G+ A ++ ++ F + T R L T Sbjct: 141 LASAESEDEVEEASKALQKDGVKIISVGVQKASEENLKAMA-TSHFHFNLRTIRDLSTFS 199 Query: 1199 QVISERVTQLTREELSRLQPVLQ---PLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLI 1255 Q +++ + +T+ + + +Q P+ S D+VFL+D S G ++++T + Sbjct: 200 QNMTQIIKDVTKYKEGAVDADMQVHFPI-SCQKDSLADLVFLVDESLGTGGNLRHLQTFL 258 Query: 1256 ERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNA 1315 E + +DV + R+ ++ +S+ K L + +++ E Q ++ L + G+ N G A Sbjct: 259 ENITSSMDVKENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQIKNLSIQVGKS-NTGAA 317 Query: 1316 LEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI----AR 1371 ++ + R+ F GSR +GVPQ VL++ SDDEV D A+ L+ V F + A Sbjct: 318 IDQMRRDGFSESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNLRLEDVNVFALSIQGAN 377 Query: 1372 NADQEELVKISLSPEYVFS-VSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPP-A 1429 N EE+V S PE S + ++ +L + K L + QI Sbjct: 378 NTQLEEIV--SYPPEQTISTLKSYADLETYSTKFLKKLQNEIWSQISTYAEQRNLDKTGC 435 Query: 1430 VESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFY 1489 V++ ADI FLID S ++ F I+ F+ + +IGP KVRVGVVQ+S+D EFY Sbjct: 436 VDTKEADIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFY 495 Query: 1490 LKTYRSQAPVLDAIRRLR-LRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVL 1548 + Y + + AI ++ L GG+ TGKAL+++ + +K+ VP +L+++ Sbjct: 496 ITDYSNDIDLRKAIFNIKQLTGGT--YTGKALDYILQ--IIKNGMKDRMSKVPCYLIVLT 551 Query: 1549 GGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEER 1608 G S D V A+ +R+ I VG ++ ELQ I V + F L +I+ Sbjct: 552 DGMSTDRVVEPAKRLRAEQITVHAVGIGAANKIELQEIAGKEERVSFGQNFDALKSIKNE 611 Query: 1609 IMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDT 1668 ++ E KADI+FL+D S + ++F+++ F+ ++ Sbjct: 612 VVREICAEKGC--------------EDMKADIMFLVDSSWSIGNENFRKMKIFMKNLLTK 657 Query: 1669 VYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINK--VVYKG---GRHANTKVGL 1723 + D Q+G+VQ++ +EF L + T+++I DAI++ ++ +G G+ N VG Sbjct: 658 IQIGADKTQIGVVQFSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTLTGKALNF-VG- 715 Query: 1724 EHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDS 1783 +F G+RL + + +IT G + +D +D + L + V +F+VGV N + Sbjct: 716 -----QYFTHSKGARLGAK--KFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANR 768 Query: 1784 EEVGKIASNSATAFRVGNVQELSELSEQVLE---TLHDAMHETLCPGVTDAAKACNLDVI 1840 ++ +I+ +S+ F V N L L +++ LHD TL LDV+ Sbjct: 769 SQLEEISGDSSLVFHVENFDHLKALERKLIFRVCALHDCKRITL------------LDVV 816 Query: 1841 LGFDGSRDQNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEA 1900 D S +K ++ D ++N +H V + V+ + + P Sbjct: 817 FVLDHSGS-----IKKQYQ---DHMIN--LTIHLVKKADVGRDRVQFGALKYSDQ-PNIL 865 Query: 1901 FDFDEY--QPEMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVK-----VVIHFTD 1953 F + Y + ++E R R T LK F + +K ++I TD Sbjct: 866 FYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKHANALFTEEHGSRIKQNVKQMLIVITD 925 Query: 1954 GADGDLADLHRASENLRQEGVRALILVGLERVVNLERLMHLEFGRGFMYDRPLRLNLLDL 2013 G D L+ + LR +G+ + VG+ + E LE G + + ++ D Sbjct: 926 GESHDHDQLNDTALELRNKGI-TIFAVGVGKANQKE----LE-GMAGNKNNTIYVDNFD- 978 Query: 2014 DYELAEQLDNIAEKACCGVPCKCSGQRGD 2042 +L + + E+ C P C Q D Sbjct: 979 --KLKDVFTLVQERMCTEAPEVCHLQEAD 1005 Score = 142 bits (359), Expect = 4e-33 Identities = 103/386 (26%), Positives = 181/386 (46%), Gaps = 18/386 (4%) Query: 31 DVKNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTE 90 D K D++F++D S +I +++ + +VK VG + F ++++ P+ Sbjct: 806 DCKRITLLDVVFVLDHSGSIKKQYQDHMINLTIHLVKKADVGRDRVQFGALKYSDQPNIL 865 Query: 91 FLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLT 150 F LNTY + ++ ++ GG T K L++ + T+ GSR V Q+++V+T Sbjct: 866 FYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKH-ANALFTEEHGSRIKQNVKQMLIVIT 924 Query: 151 DG--HSKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHD 208 DG H D L + EL++ + +FA+GV A++ L+ +A N ++NF L D Sbjct: 925 DGESHDHDQLNDTALELRNKGITIFAVGVGKANQKELEGMAGNKNN--TIYVDNFDKLKD 982 Query: 209 IVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNL 268 + LV + +PE + AD+IFL DGS+ + +F + FL +L Sbjct: 983 VF-TLVQERMCTEAPE----------VCHLQEADVIFLCDGSDRVSNSDFVTMTTFLSDL 1031 Query: 269 LEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDF 328 ++ I +Q++++G+ QF +++ L TK Q ++ + +GG I AL Sbjct: 1032 IDNFDIQSQRMKIGMAQFGSNYQSIIELKNSLTKTQWKTQIQNVSKSGG-FPRIDFALK- 1089 Query: 329 VVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAE 388 V N F G R GVPQ LV+I++G ++ V LK + LG + Sbjct: 1090 KVSNMFNLHAGGRRNAGVPQTLVVITSGDPRYDVADAVKTLKDLGICVLVLGIGDVYKEH 1149 Query: 389 LQHIATDDNLVFTVPEFRSFGDLQEK 414 L I + + T +F ++ K Sbjct: 1150 LLPITGNSEKIITFQDFDKLKNVDVK 1175 Score = 101 bits (252), Expect = 1e-20 Identities = 62/219 (28%), Positives = 110/219 (50%), Gaps = 1/219 (0%) Query: 2618 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2677 +D+AF++D+++ +F E+K +I ++ ++P P S RVAV+ ++P + N Sbjct: 2290 MDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPN 2349 Query: 2678 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLK 2737 PV +EF L Y S ++ L QL G +G A+++TI+NVF PN R K Sbjct: 2350 TEECPVYLEFDLVTYNSIHQMKHHLQDSQ-QLNGDVFIGHALQWTIDNVFVGTPNLRKNK 2408 Query: 2738 IVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKL 2797 ++ ++ GE + + V L+AKC+GY V G K N KE+ AS P D Sbjct: 2409 VIFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHNDKELEELASHPLDHHLVQ 2468 Query: 2798 VDKSTELNEEPLMRFGRLLPSFVSSENAFYLSPDIRKQC 2836 + ++ + + +++F + + Y + D++ C Sbjct: 2469 LGRTHKPDWNYIIKFVKPFVHLIRRAINKYPTEDMKATC 2507 Score = 55.1 bits (131), Expect = 1e-06 Identities = 74/400 (18%), Positives = 151/400 (37%), Gaps = 59/400 (14%) Query: 39 DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGEND----FHFALVQFNGNPHTEFLLN 94 +++F +D+S+ + EE F R+ + +V L + EN+ A+V +N + Sbjct: 1758 ELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNSGTSYLIRWS 1817 Query: 95 TYRTKQEVLSHISNMSYIGGT--NQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDG 152 Y K+++L +S + Y T G + ++ ++ + + AG V +V V ++G Sbjct: 1818 DYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKR---TYAGANVRRVAVFFSNG 1874 Query: 153 H--SKDGLALPSAELKSADVNVFAIGVEDA--------DEGALKEIASEPLNMHMFNLEN 202 S+ + + E + D++ ++ D ++ P N LE Sbjct: 1875 QTASRSSIITATMEFSALDISPTVFAFDERVFLEAFGFDNTGTFQVIPVPPNGENQTLER 1934 Query: 203 FTSLHDIVGNLV--SCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAV 260 +C+ + PE D++FLID S N F Sbjct: 1935 LRRCALCYDKCFPNACIREAFLPE-------------DSYMDVVFLIDNSRNIAKDEFKA 1981 Query: 261 ILDFLVNLLEKLPIGTQQI------RVGVVQFS---------DEPRTMFSLDTYSTKAQV 305 + + ++++ I + + R+ ++ +S +T F TY + + Sbjct: 1982 VKALVSSVIDNFNIASDPLISDSGDRIALLSYSPWESSRRKMGTVKTEFDFITYDNQLLM 2041 Query: 306 LGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYG 365 ++ A IG AL + EN F R +V+ ++SAG + + + Sbjct: 2042 KNHIQTSFQQLNGEATIGRALLWTTENLFPETPYLRKH----KVIFVVSAGENYERKEFV 2097 Query: 366 VVALKQAS-----VFSFGLGA-QAASRAELQHIATDDNLV 399 + +A +F LG+ + EL D +L+ Sbjct: 2098 KMMALRAKCQGYVIFVISLGSTRKDDMEELASYPLDQHLI 2137 Score = 52.8 bits (125), Expect = 5e-06 Identities = 81/390 (20%), Positives = 155/390 (39%), Gaps = 54/390 (13%) Query: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKL-------PIGTQQIRVGVVQFSDEPRTMF 294 +++F +D S + +F D + +++ L P+G RV +V ++ + Sbjct: 1758 ELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGA---RVAMVSYNSGTSYLI 1814 Query: 295 SLDTYSTKAQVLGAVKALGFAGG-ELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLI 353 Y+ K Q+L + + + E ++G A+ FV N F R V +V V Sbjct: 1815 RWSDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYAGA---NVRRVAVFF 1871 Query: 354 SAGPSSDEIRYGVVALK------QASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRS 407 S G ++ ++ +VF+F R L+ D+ F V Sbjct: 1872 SNGQTASRSSIITATMEFSALDISPTVFAFD------ERVFLEAFGFDNTGTFQVIPVPP 1925 Query: 408 FGDLQEKLLPYIVGVAQRHIVLKPPTIVTQVI--EVNKRDIVFLVDGSSALGLANFNAIR 465 G+ Q L + A + P + + E + D+VFL+D S + F A++ Sbjct: 1926 NGENQT--LERLRRCALCYDKCFPNACIREAFLPEDSYMDVVFLIDNSRNIAKDEFKAVK 1983 Query: 466 DFIAKVIQRLEIGQDLI------QVAVAQYA---------DTVRPEFYFNTHPTKREVIT 510 ++ VI I D + ++A+ Y+ TV+ EF F T+ + + Sbjct: 1984 ALVSSVIDNFNIASDPLISDSGDRIALLSYSPWESSRRKMGTVKTEFDFITYDNQLLMKN 2043 Query: 511 AVR-KMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDE---IS 566 ++ + L+G A G AL + NLF + R K++ +++ G++ + + Sbjct: 2044 HIQTSFQQLNGEAT-IGRALLWTTENLFPETPYLRK----HKVIFVVSAGENYERKEFVK 2098 Query: 567 QPAQELKRSSIMAFAIGNKGADQAELEEIA 596 A K + F I + ++EE+A Sbjct: 2099 MMALRAKCQGYVIFVISLGSTRKDDMEELA 2128 Score = 44.3 bits (103), Expect = 0.002 Identities = 39/192 (20%), Positives = 87/192 (45%), Gaps = 23/192 (11%) Query: 28 QQADVKNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSL------AVGENDFHFALV 81 ++A + + D++FL+D+S I ++ F+ V+ + V+ + + ++ AL+ Sbjct: 1952 REAFLPEDSYMDVVFLIDNSRNIAKDEFKAVKALVSSVIDNFNIASDPLISDSGDRIALL 2011 Query: 82 QFN---------GNPHTEFLLNTYRTKQEVLSHI-SNMSYIGGTNQTGKGLEYIMQSHLT 131 ++ G TEF TY + + +HI ++ + G G+ L + ++ Sbjct: 2012 SYSPWESSRRKMGTVKTEFDFITYDNQLLMKNHIQTSFQQLNGEATIGRALLWTTENLFP 2071 Query: 132 KAAGSRAGDGVPQVIVVLTDGHS---KDGLALPSAELKSADVNVFAIGVEDADEGALKEI 188 + R +VI V++ G + K+ + + + K +F I + + ++E+ Sbjct: 2072 ETPYLRK----HKVIFVVSAGENYERKEFVKMMALRAKCQGYVIFVISLGSTRKDDMEEL 2127 Query: 189 ASEPLNMHMFNL 200 AS PL+ H+ L Sbjct: 2128 ASYPLDQHLIQL 2139 Score = 44.3 bits (103), Expect = 0.002 Identities = 41/180 (22%), Positives = 79/180 (43%), Gaps = 19/180 (10%) Query: 39 DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDF------HFALVQFNG---NPHT 89 D+ FL+D+S +G + F+ V+ F+ V+ + A++ ++ P+T Sbjct: 2291 DVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPNT 2350 Query: 90 -------EFLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGV 142 EF L TY + ++ H+ + + G G L++ + + R + Sbjct: 2351 EECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLRKNKVI 2410 Query: 143 PQVIVVLTDGHSKDGLALPS--AELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNL 200 + T+ KD L S A+ + + VF+ G + D+ L+E+AS PL+ H+ L Sbjct: 2411 FVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHNDK-ELEELASHPLDHHLVQL 2469 Score = 38.1 bits (87), Expect = 0.14 Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 17/116 (14%) Query: 1436 DIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKV------RVGVVQFSN------- 1482 D+ FLID+S+ V D F ++ F++ ++ +I P+ + RV V+ +S Sbjct: 2291 DVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPNT 2350 Query: 1483 ---DVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSR 1535 V+ EF L TY S + ++ + G + G AL++ N+FV + R Sbjct: 2351 EECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGD-VFIGHALQWTIDNVFVGTPNLR 2405 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 336 bits (862), Expect = 2e-91 Identities = 267/837 (31%), Positives = 388/837 (46%), Gaps = 126/837 (15%) Query: 1639 DIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFST 1698 D+VFLLD S + ++ F++V ++V+ +VDT D +VG+V+Y+ PT F L F + Sbjct: 38 DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGS 97 Query: 1699 KRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSR-LDQRVPQIAFVITGGKSVE 1757 + ++ A ++ Y GG + NT L ++ F P AG R D+ Q+A ++T G+S + Sbjct: 98 QEEVKAAARRLAYHGG-NTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQD 156 Query: 1758 DAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIAS--NSATAFRVGNVQELSELSEQVLET 1815 D + A + G+++FAVGV EE+ +IAS SA F V + + ++ ++ Sbjct: 157 LVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRGKLRRR 216 Query: 1816 LHDAMHETLCPGVT---DAAKACNLDVILGFDGSRDQNVFVAQKGFESKVDAILNRISQM 1872 L LCP V D K N G+++ F F V IL + Sbjct: 217 L---CENVLCPSVRVEGDRFKHTN-------GGTKEITGFDLMDLF--SVKEILGKRE-- 262 Query: 1873 HRVSCSGGRSPTVRVS---VVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQHPYVLTE-- 1927 +G +S VR+ VV +T + DEY +FR + + + + Sbjct: 263 -----NGAQSSYVRMGSFPVVQSTEDVFPQGLP-DEYAFVTTFRFRKTSRKEDWYIWQVI 316 Query: 1928 DTLKVYLNKFR-------------QSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGV 1974 D + R + D+V+VV + D D H+ + +++ + V Sbjct: 317 DQYSIPQVSIRLDGENKAVEYNAVGAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNV 376 Query: 1975 RALILVGLERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQL----DNIAE-KAC 2029 I L + + +E +++ + + L + + +D++L + AE + C Sbjct: 377 SLHIDCALVQTLPIEERENIDIQGKTVIGKRL-YDSVPIDFDLQRIVIYCDSRHAELETC 435 Query: 2030 CGV---PCKC-------------------SGQRGDRGPIGSIGPKGIPGEDGY---RGYP 2064 C + PC+ S Q G I P G GE G G P Sbjct: 436 CDIPSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLP 495 Query: 2065 GDEG----------------------GPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGE 2102 G +G GP +G G G+ G G PG+ G KG RG PGE Sbjct: 496 GPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGE 555 Query: 2103 KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQ 2162 GE G G G+ G G GLPG G G PG +G++G +G +GE+G+ G+ G PG PG Sbjct: 556 LGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGD 615 Query: 2163 DSQE--------RGPKGETGDLGPMGVPG-------RDGVPGGPGETGKNGGFGRRGPPG 2207 Q+ GP+GE GD+GP G PG ++G+ G G G G G GPPG Sbjct: 616 TGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPG 675 Query: 2208 AKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQ------GISGPRGSGGAAGAPG 2261 A+G G G+ G G QG RG +G GP G PGL+G Q G+ GP G GG+ G PG Sbjct: 676 ARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPG 735 Query: 2262 E---RGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPG 2317 E G+ GP G G PG+ GP G G G +GE G+ G DG+ G G RG+ GE+G G Sbjct: 736 EIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAG 795 Query: 2318 YPGPKGN---PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 PG KG PG PG G G KG +G +G G PG+ G +G+ G GPAGP G G Sbjct: 796 RPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPG 852 Score = 275 bits (704), Expect = 4e-73 Identities = 158/365 (43%), Positives = 193/365 (52%), Gaps = 27/365 (7%) Query: 2030 CGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEG-------GPGERGPPGVNGTQ 2082 C P G+ G GP+G GPKG G G G PG +G GP +G G G+ Sbjct: 476 CSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSL 535 Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142 G G PG+ G KG RG PGE GE G G G+ G G GLPG G G PG +G++G + Sbjct: 536 GLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEK 595 Query: 2143 GEKGERGDVGIRGDPGNPGQDSQE--------RGPKGETGDLGPMGVPG-------RDGV 2187 G +GE+G+ G+ G PG PG Q+ GP+GE GD+GP G PG ++G+ Sbjct: 596 GTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGL 655 Query: 2188 PGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGI 2247 G G G G G GPPGA+G G G+ G G QG RG +G GP G PGL+G QG Sbjct: 656 KGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGP 715 Query: 2248 SGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRR 2307 GP G G G G G G +G G+PG PGP G G GP G G G ++G Sbjct: 716 PGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPG-----TKGEP 770 Query: 2308 GKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPK 2367 G++GE G PG PG +G GE GL G G KG G G G PG+ G+KGD G G G Sbjct: 771 GERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLP 830 Query: 2368 GNRGD 2372 G +GD Sbjct: 831 GLKGD 835 Score = 270 bits (689), Expect = 2e-71 Identities = 173/418 (41%), Positives = 208/418 (49%), Gaps = 69/418 (16%) Query: 2024 IAEKACCGVP-----CKCSGQ--RGDRGPIGSIGPKGIPGEDGY--RGYPGDEGGPGERG 2074 + KA CG C GQ +GDRG G G G G+ G G PG G PG++G Sbjct: 1001 LGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKG 1060 Query: 2075 PPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGL------------------DG 2116 PG G GF G G G G+ G PGE+G G+ GL L G Sbjct: 1061 SPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPG 1120 Query: 2117 EDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPG-QDSQ-ERGPKGETG 2174 G GLPG G+KG PG+ G +G G+KGE G G+ G PG G Q SQ ERG GE G Sbjct: 1121 PPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVG 1180 Query: 2175 ---DLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKG--------GP-GQPGFEG 2222 D G GVPG G PG PG G +G G GPPG +G+ G GP G PG G Sbjct: 1181 QKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPG 1240 Query: 2223 EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGA---------AGAPGERGRTGPLGRKG 2273 E+G G G GP G PG GE G+ GP G+ G +GAPG RG +G +G G Sbjct: 1241 EEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPG 1300 Query: 2274 EPGEPG---------PKGGIGNRGPRGETGDDGRDGV----GSEGRRGKKGERGFPGYPG 2320 + G PG P+G G RGP G+ G G G G+ G++G KGE G PG PG Sbjct: 1301 QEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPG 1360 Query: 2321 ---PKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSID 2375 P+G PGEPG G G +G+ G+ G PG G++GDPG G GP G +G D Sbjct: 1361 FLGPRGPPGEPGEKGVPGKEGVPGKPGE---PGFKGERGDPGIKGDKGPPGGKGQPGD 1415 Score = 267 bits (682), Expect = 1e-70 Identities = 166/375 (44%), Positives = 196/375 (52%), Gaps = 51/375 (13%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGG---PGERGPPGVNGTQGFQGCPGQRGVK 2094 G G GP G G G+PGE G+ G PG G PG+ GP G G G +G PG+RG Sbjct: 717 GPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGED 776 Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGE---------K 2145 G G PG +GE+GE GL G GE G+ GLPG+ G G G +GD+G +GE + Sbjct: 777 GLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDR 836 Query: 2146 GERGDVGIRGDPGNPGQDSQ---------ERGPKGETGDLGPMGVPGRDGVPGGPGETGK 2196 GE+G+ G G PG PG S E+GPKGE GD G+PG G+ G PGE G Sbjct: 837 GEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGD---PGLPGEPGLQGRPGELGP 893 Query: 2197 NGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGI------SGP 2250 G GPPGAKG +G G PG G G G G GP+GPPG +G G+ G Sbjct: 894 QGP---TGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGE 950 Query: 2251 RGSGGAAGAPGERGRTGPLGRKGEPGEPGP--KGGIGNRGPRGETGDDGRDGV------- 2301 RG GAAG G G GP G G PG PGP KG G G RG G G G Sbjct: 951 RGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKV 1010 Query: 2302 -GSE----GRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKG 2356 GSE G + KG+RG PG PG G+ G+PG+ G GP G G G+ G P G +G Sbjct: 1011 RGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSGPPGDKGSP---GSRG 1066 Query: 2357 DPGYPGPAGPKGNRG 2371 PG+PGP GP G G Sbjct: 1067 LPGFPGPQGPAGRDG 1081 Score = 256 bits (654), Expect = 2e-67 Identities = 162/392 (41%), Positives = 191/392 (48%), Gaps = 61/392 (15%) Query: 2038 GQRGDRG------PIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGT-------QGF 2084 G++G+RG G G +G PG G G G++G G GPPGV G+ +G Sbjct: 599 GEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGE 658 Query: 2085 QGCPGQRGVKGSRGFPGEKGEVGEIGLDG------LDGEDGDKGLPGS------SGEKGN 2132 QG PG RG +G+ G PG +G +G G DG L G+ GD G PG G G Sbjct: 659 QGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGP 718 Query: 2133 PGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPG--------- 2183 PG G GP G G G++G G PG PG GP G+ G GP G PG Sbjct: 719 PGVPGPPGPGGSPGLPGEIGFPGKPGPPGPT----GPPGKDGPNGPPGPPGTKGEPGERG 774 Query: 2184 RDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIG 2243 DG+PG PG G+ G G G PG KG G PG PGF G +G +G QG G G PGL G Sbjct: 775 EDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKG 834 Query: 2244 EQGISGPRGSGGAAGAPGER----------GRTGPLGRKGEPG---EPGPKGGIGNRGPR 2290 ++G G G G G PG G GP G KG+PG EPG +G G GP+ Sbjct: 835 DRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQ 894 Query: 2291 GETGDDGRDGV-------GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRR 2343 G TG G G G+ G G G G PG GP G+ G PGL GT G G RG + Sbjct: 895 GPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEK 954 Query: 2344 G---NSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 G G PG VG +GDPG PG GP G D Sbjct: 955 GAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKD 986 Score = 254 bits (648), Expect = 1e-66 Identities = 169/419 (40%), Positives = 198/419 (47%), Gaps = 69/419 (16%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQ-------------- 2082 SG GD+G GS G G PG G G G G PGERGPPG G Sbjct: 1053 SGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKD 1112 Query: 2083 -------GFQGCPGQRGVKGSRGFPGE------KGEVGEIGLDGLDGEDGDKGLPGSSGE 2129 G G PG G KG +G PG+ +G+ GE G GL G G G GS GE Sbjct: 1113 VCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGE 1172 Query: 2130 KGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQD-----SQERGPKGETGDLGPMGVPGR 2184 +G G G KG +G G G +G G+PG PG D + G +G G GP G G Sbjct: 1173 RGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGP 1232 Query: 2185 DGVPGGPGETGKNGGFGRRGPPGAKGNKGGPG---------QPGFEGEQGTRGAQGPAGP 2235 G+PG PGE GK G G+ GPPG G G PG PGF+G G GA GP G Sbjct: 1233 SGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGE 1292 Query: 2236 AGPPGLIGEQGI---------------SGPRGSGGAAGAPGERGRTGPLGR------KGE 2274 +G GL G++G+ GPRG G G+PG G GP G KGE Sbjct: 1293 SGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGE 1352 Query: 2275 PGEPGPKGGIGNRGPRGETGDDG---RDGV-GSEGRRGKKGERGFPGYPG---PKGNPGE 2327 G PG G +G RGP GE G+ G ++GV G G G KGERG PG G P G G+ Sbjct: 1353 NGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQ 1412 Query: 2328 PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDK 2386 PG G G KG G G G PG G G PG PG G G RG+S L + I+++ Sbjct: 1413 PGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEE 1471 Score = 253 bits (645), Expect = 3e-66 Identities = 173/453 (38%), Positives = 206/453 (45%), Gaps = 77/453 (16%) Query: 2031 GVPCK-----CSGQRGDRGPIGSIGPKGIPG---EDGYRGYPGDEGGPGERGPPGVNGTQ 2082 GVP K G++G+ GP G GP GI G G RG G+ G G++G PGV G Sbjct: 1135 GVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFM 1194 Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142 G G PG G G G G G G G +G G G GLPG GE+G GR G GP Sbjct: 1195 GPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPP 1254 Query: 2143 GEKGERGDVGI------RGDPGNPGQ--DSQERGPKGETGDLGPMGVPGRDGVPGGPGET 2194 GE G+ G+ G+ RG PG G DS GP+GE+G MG+PG++G+PG G+T Sbjct: 1255 GEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESG---AMGLPGQEGLPGKDGDT 1311 Query: 2195 GKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSG 2254 G G G +GP G G G PG PG G GT G +G G G PGL G G GP G Sbjct: 1312 GPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEP 1371 Query: 2255 GAAGAPGERG---RTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG----VGSEGRR 2307 G G PG+ G + G G KGE G+PG KG G G +G+ GD G G G G + Sbjct: 1372 GEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQ 1431 Query: 2308 GKKGERGFPGYPGPKGNPGEPGLNGTT--------------------------------- 2334 G GE G G PGP G PG PGL G + Sbjct: 1432 GLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAY 1491 Query: 2335 --------------GPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALI 2380 G G+ GR G G PG GQ G G GP GPKG RG D A Sbjct: 1492 MKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG 1551 Query: 2381 QSIKDKCPCCYGPLECPVFPTELAFALDTSEGV 2413 ++ + GP P P E +A D G+ Sbjct: 1552 VGLRGE----MGPPGIPGQPGEPGYAKDGLPGI 1580 Score = 252 bits (644), Expect = 4e-66 Identities = 154/358 (43%), Positives = 181/358 (50%), Gaps = 23/358 (6%) Query: 2024 IAEKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQG 2083 +A+ C P G G G G G G PG +G G G+ G PG GPPG+ G QG Sbjct: 1109 LAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQG 1168 Query: 2084 FQ---GCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKG 2140 Q G G+ G KG +G PG G +G G G G DG G G G +G+PG+ G G Sbjct: 1169 SQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPG 1228 Query: 2141 PRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGF 2200 P+G G GI G+ G G+D + GP GE G G G+PG +G G PG G G Sbjct: 1229 PQGPSGL---PGIPGEEGKEGRDGKP-GPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDS 1284 Query: 2201 GRRGPPGAKGNKGGPGQ---PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAA 2257 G GP G G G PGQ PG +G+ G G QGP GP GPP G GS G+ Sbjct: 1285 GAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPP---------GKNGSPGSP 1335 Query: 2258 GAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGD---DGRDGV-GSEGRRGKKGER 2313 G PG G G G KGE G PG G +G RGP GE G+ G++GV G G G KGER Sbjct: 1336 GEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGER 1395 Query: 2314 GFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 G PG G KG PG G G G G +G G GP G+ G+ G G PGP G G G Sbjct: 1396 GDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPG 1453 Score = 250 bits (639), Expect = 1e-65 Identities = 167/427 (39%), Positives = 196/427 (45%), Gaps = 93/427 (21%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGY---PGDEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094 G+ G GP G G GIPGE+G G PG G PG+ G PG+ G +G +G PG +G Sbjct: 1222 GKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHT 1281 Query: 2095 GSRGFPGEKGEVGEIGL---DGLDGEDGDKGLPGSSG---------EKGNPGRRGDKGPR 2142 G G PG +GE G +GL +GL G+DGD G G G + G+PG G+ GP Sbjct: 1282 GDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPS 1341 Query: 2143 GEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGR 2202 G G++G G G PG PG GP+G G+ G GVPG++GVPG PGE G G G Sbjct: 1342 GTPGQKGSKGENGSPGLPGF----LGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGD 1397 Query: 2203 ------RGPPGAKGNKGGPGQPGFEGEQGTRGAQG------PAGPAGPPGLIG------- 2243 +GPPG KG G PG PG +G G G QG P GP GPPG G Sbjct: 1398 PGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGE 1457 Query: 2244 -------------------------------------EQGISGPRGSGGAAGAPGERGRT 2266 QG GP G G G PG G Sbjct: 1458 SPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPM 1517 Query: 2267 GPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPG 2326 G GR G+ G GP G IG +G RG GD G GV G +GE G PG P G PG Sbjct: 1518 GEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGV------GLRGEMGPPGIP---GQPG 1568 Query: 2327 EPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDK 2386 EPG G GI G +G +GP G PG PGP GP G S QCA S+ + Sbjct: 1569 EPGY-AKDGLPGIPGPQGETGP------AGHPGLPGPPGPPGQCDPS--QCAYFASLAAR 1619 Query: 2387 CPCCYGP 2393 GP Sbjct: 1620 PGNVKGP 1626 Score = 250 bits (638), Expect = 2e-65 Identities = 166/441 (37%), Positives = 196/441 (44%), Gaps = 94/441 (21%) Query: 2026 EKACCGVPCK--CSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGE---------RG 2074 EK G+P + G+ G+ GP G GP G G++G G PG G PG G Sbjct: 872 EKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSG 931 Query: 2075 PPGVNGTQGFQGCPG---QRGVKGS---RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSG 2128 PPG G G +G PG +RG KG+ G PG G G+ G GL G G KG G G Sbjct: 932 PPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPG 990 Query: 2129 EKGNPGRRGD-----------------------KGPRGEKGERGDVGIRGDPG------- 2158 +G+PG G KG RG G G G RGDPG Sbjct: 991 LRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPP 1050 Query: 2159 ---NPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNG--GF------------- 2200 P D G +G G GP G GRDG PG PGE G G G Sbjct: 1051 GPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLA 1110 Query: 2201 ------------GRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGIS 2248 G G PG KG+KG PG+PG EG +G +G GP G GPPG+ G QG Sbjct: 1111 KDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQ 1170 Query: 2249 GPRGSGGAAGAPGERGRTGPLGRKGEPGEPGP---------------KGGIGNRGPRGET 2293 G RG+ G G G++G G G G PG PGP +G G GP G Sbjct: 1171 GERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQ 1230 Query: 2294 GDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIV 2352 G G G+ G EG+ G+ G+ G PG PG G PG PG G GP G +G G+SG PG Sbjct: 1231 GPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPR 1290 Query: 2353 GQKGDPGYPGPAGPKGNRGDS 2373 G+ G G PG G G GD+ Sbjct: 1291 GESGAMGLPGQEGLPGKDGDT 1311 Score = 248 bits (632), Expect = 9e-65 Identities = 158/427 (37%), Positives = 201/427 (47%), Gaps = 92/427 (21%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGE------RGPPGVNGTQGFQG 2086 P G+RG G +G G +G PG G+ G PG+ G PG GPPG+ G+ G +G Sbjct: 1166 PQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEG 1225 Query: 2087 CPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDG---DKGLPGSSGEKGNPGRRG---DKG 2140 PG +G G G PGE+G+ G G G GE G + GLPG G +G PG +G D G Sbjct: 1226 PPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSG 1285 Query: 2141 PRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGF 2200 G +GE G +G+ G G PG+D + GP G G GP G PG++G PG PGE G +G Sbjct: 1286 APGPRGESGAMGLPGQEGLPGKDG-DTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTP 1344 Query: 2201 GRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAP 2260 G++G +KG G PG PGF G +G G G G G G+ G+ G G +G G G Sbjct: 1345 GQKG---SKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIK 1401 Query: 2261 GERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-------GSEGRRGK---- 2309 G++G G G+ G+PG PG KG G GP+G G++G G G G RG+ Sbjct: 1402 GDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSM 1461 Query: 2310 -------------------------------KGERGFPGYPGP---------------KG 2323 K +G PG PGP G Sbjct: 1462 ETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPG 1521 Query: 2324 NPGEPGLNGTTGPKGIRGR--------------RGNSGPPGIVGQKGDPGY-----PGPA 2364 PG+ GL G +GP G +G RG GPPGI GQ G+PGY PG Sbjct: 1522 RPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIP 1581 Query: 2365 GPKGNRG 2371 GP+G G Sbjct: 1582 GPQGETG 1588 Score = 239 bits (611), Expect = 2e-62 Identities = 157/395 (39%), Positives = 182/395 (46%), Gaps = 62/395 (15%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGD--EGGPGERGPPGVNG----------TQGFQ 2085 G G+ G G +GP+G PG G G PG +G PG RG PG+ G +G + Sbjct: 955 GAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSE 1014 Query: 2086 GCP-------GQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGD 2138 C G RG G G PG +G+ G IG+ G G G G GS G +G PG G Sbjct: 1015 NCALGGQCVKGDRGAPGIPGSPGSRGDPG-IGVAGPPGPSGPPGDKGSPGSRGLPGFPGP 1073 Query: 2139 KGPRGEKGERGDVGIRGDPGNPG--------------QDSQERGPKGETGDLGPMGVPGR 2184 +GP G G G+ G RG PG PG +D P G G G G G Sbjct: 1074 QGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGD 1133 Query: 2185 DGVPGGPGETGKNGGFGRRGPPGAKGNKG--GP-------------GQPGFEGEQGTRGA 2229 GVPG PG G G G GPPG G G GP GQ G +G G G Sbjct: 1134 KGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGF 1193 Query: 2230 QGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGP 2289 GP G GPPG G G +GP G G+ G G G GP G G PGE G +G G GP Sbjct: 1194 MGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGP 1253 Query: 2290 RGETGDDGRDGV-GSEGRRGK---KGERGFPGYPGPKGNPGE---------PGLNGTTGP 2336 GE G G G+ G EG RG KG G G PGP+G G PG +G TGP Sbjct: 1254 PGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGP 1313 Query: 2337 KGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 G +G +G GPPG G G PG PGP+G G +G Sbjct: 1314 TGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKG 1348 Score = 129 bits (324), Expect = 5e-29 Identities = 90/254 (35%), Positives = 138/254 (54%), Gaps = 29/254 (11%) Query: 628 SGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTP 687 +G VH D++FLLD S++VGK +F VR +V NLV++ ++G D RVG+V++SD P Sbjct: 30 AGCKSVHY---DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRP 86 Query: 688 VTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHV-PQL 746 T F L + ++ ++ R+L GG+ NTG AL Y+ A F+ G R R+ Q+ Sbjct: 87 TTAFELGLFGSQEEVKAAARRLAYHGGN-TNTGDALRYITARSFSPHAGGRPRDRAYKQV 145 Query: 747 LLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNP--SLVYLMDDFSS 804 +LLT G+S+D L AA A RAGI F VG +A K ELE+IA P + V+ + DF++ Sbjct: 146 AILLTDGRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNA 205 Query: 805 LPALPQQLIQPLT---------------TYVSGGVEEV---PLAQPESKRDILFLFDGSA 846 + + +L + L + +GG +E+ L S ++IL + A Sbjct: 206 IDKIRGKLRRRLCENVLCPSVRVEGDRFKHTNGGTKEITGFDLMDLFSVKEILGKRENGA 265 Query: 847 N----LVGQFPVVR 856 +G FPVV+ Sbjct: 266 QSSYVRMGSFPVVQ 279 Score = 115 bits (288), Expect = 7e-25 Identities = 74/227 (32%), Positives = 124/227 (54%), Gaps = 10/227 (4%) Query: 26 QQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNG 85 Q Q+A K+ D++FL+D+S ++G+E F+ VR+++ ++V + VG + +V+++ Sbjct: 26 QAQRAGCKS-VHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSD 84 Query: 86 NPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGD-GVPQ 144 P T F L + +++EV + ++Y GG TG L YI + AG R D Q Sbjct: 85 RPTTAFELGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQ 144 Query: 145 VIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFT 204 V ++LTDG S+D + +A A + +FA+GV +A + L+EIASEP + H+F++ +F Sbjct: 145 VAILLTDGRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFN 204 Query: 205 SLHDIVGNL-------VSCVHSSVSPERAGDTE-TLKDITAQDSADI 243 ++ I G L V C V +R T K+IT D D+ Sbjct: 205 AIDKIRGKLRRRLCENVLCPSVRVEGDRFKHTNGGTKEITGFDLMDL 251 Score = 99.8 bits (247), Expect = 4e-20 Identities = 71/183 (38%), Positives = 82/183 (44%), Gaps = 42/183 (22%) Query: 2232 PAGPAGPP-------GLIGEQGISGPRGSGGAAGAPGERGRTGP---LGRKGEPGEPGPK 2281 P P PP G + S P G G G G G GP +G G G PGPK Sbjct: 454 PPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPK 513 Query: 2282 G-----GIG--NRGPRGETGDDGRDGV----GSEGRRGKKGE---------------RGF 2315 G GIG +G +GE G G G GS+G RG+ GE +G Sbjct: 514 GEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGP 573 Query: 2316 PGYPGPKGNPGEPGLNGTTGPKGIRGRRGN------SGPPGIVGQKGDPGYPGPAGPKGN 2369 PG PGP G G PGL G G KG RG +G G PG GQ+G PG G AGP+G Sbjct: 574 PGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGE 633 Query: 2370 RGD 2372 +GD Sbjct: 634 KGD 636 Score = 99.4 bits (246), Expect = 5e-20 Identities = 89/266 (33%), Positives = 129/266 (48%), Gaps = 27/266 (10%) Query: 1233 DVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSS 1291 D+VFL+D S S G E F+ VR + LVD +VG D TRV V+++SD P F L S Sbjct: 38 DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGS 97 Query: 1292 KDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSR-IEEGVPQFLVLISSGKSDD 1350 ++EV+ A +RL GG N G+AL Y++ F G R + Q +L++ G+S D Sbjct: 98 QEEVKAAARRLAYHGG-NTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQD 156 Query: 1351 EVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSPE--YVFSVSTFRELPSLEQKLLTP 1407 V D A + G+ F + A +EEL +I+ P+ +VF VS F + + KL Sbjct: 157 LVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRGKLR-- 214 Query: 1408 ITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDF-VSRIVRRL 1466 ++L + P VE D F + GF + F V I+ + Sbjct: 215 ---------RRLCENVLCPSVRVEGDR----FKHTNGGTKEITGFDLMDLFSVKEILGKR 261 Query: 1467 NIG--PSKVRVG---VVQFSNDVFPE 1487 G S VR+G VVQ + DVFP+ Sbjct: 262 ENGAQSSYVRMGSFPVVQSTEDVFPQ 287 Score = 95.1 bits (235), Expect = 1e-18 Identities = 55/177 (31%), Positives = 95/177 (53%), Gaps = 4/177 (2%) Query: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 301 D++FL+D S++ G +F + ++ NL++ +G + RVGVV++SD P T F L + + Sbjct: 38 DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGS 97 Query: 302 KAQVLGAVKALGFAGGELANIGLALDFVVENHFT-RAGGSRVEEGVPQVLVLISAGPSSD 360 + +V A + L + GG N G AL ++ F+ AGG + QV +L++ G S D Sbjct: 98 QEEVKAAARRLAYHGGN-TNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQD 156 Query: 361 EIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNL--VFTVPEFRSFGDLQEKL 415 + A +A + F +G A + EL+ IA++ VF V +F + ++ KL Sbjct: 157 LVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRGKL 213 Score = 93.2 bits (230), Expect = 4e-18 Identities = 62/189 (32%), Positives = 94/189 (49%), Gaps = 4/189 (2%) Query: 1436 DIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRS 1495 D+VFL+D+S V + F +R +V+ +V +GP + RVGVV++S+ F L + S Sbjct: 38 DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGS 97 Query: 1496 QAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIED-GVPQHLVLVLGGKSQD 1554 Q V A RRL GG+ NTG AL ++ F AG R D Q +L+ G+SQD Sbjct: 98 QEEVKAAARRLAYHGGN-TNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQD 156 Query: 1555 DVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRL--VFTVREFRELPNIEERIMNS 1612 V A +GI VG + EL+ I ++P+ VF V +F + I ++ Sbjct: 157 LVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRGKLRRR 216 Query: 1613 FGPSAATPA 1621 + P+ Sbjct: 217 LCENVLCPS 225 Score = 86.3 bits (212), Expect = 4e-16 Identities = 64/180 (35%), Positives = 94/180 (52%), Gaps = 7/180 (3%) Query: 1012 LLKSVHNGAPAPVSGEK----DVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVR 1066 LL S G A +G K D+VFLLD S V + F ++++V +V++ +VG DR R Sbjct: 17 LLWSGGGGCQAQRAGCKSVHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTR 76 Query: 1067 VAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGS 1126 V VV+YSDR F L + ++++V A R+L GG T NTG AL ++ AG Sbjct: 77 VGVVRYSDRPTTAFELGLFGSQEEVKAAARRLAYHGGNT-NTGDALRYITARSFSPHAGG 135 Query: 1127 RITE-GVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFA 1185 R + Q+ I+LT RS D V + + R G +G+G A E++ I+ P A Sbjct: 136 RPRDRAYKQVAILLTDGRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSA 195 Score = 85.1 bits (209), Expect = 1e-15 Identities = 62/201 (30%), Positives = 102/201 (50%), Gaps = 10/201 (4%) Query: 445 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 504 D+VFL+D SS++G +F +R ++A ++ E+G D +V V +Y+D F + Sbjct: 38 DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGS 97 Query: 505 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAE-GIPKLLVLITGGKSLD 563 + EV A R++ G TG AL ++ F+ AG R + ++ +L+T G+S D Sbjct: 98 QEEVKAAARRL-AYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQD 156 Query: 564 EISQPAQELKRSSIMAFAIGNKGADQAELEEIAFD--SSLVFIPAEFRAA-PLQGML--- 617 + A R+ I FA+G A + ELEEIA + S+ VF ++F A ++G L Sbjct: 157 LVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRGKLRRR 216 Query: 618 --PGLLAPLRTLSGTPEVHSN 636 +L P + G H+N Sbjct: 217 LCENVLCPSVRVEGDRFKHTN 237 Score = 61.6 bits (148), Expect = 1e-08 Identities = 48/156 (30%), Positives = 71/156 (45%), Gaps = 3/156 (1%) Query: 837 DILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQS 895 D++FL D S+++ + F VR ++ ++D V P+ TR+ V +YSD S Sbjct: 38 DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGS 97 Query: 896 KPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIED-GVLQFLVLLVAGRSSD 954 + E+ +R+ G N G AL Y F AG R D Q +LL GRS D Sbjct: 98 QEEVKAAARRLAYHGGNT-NTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQD 156 Query: 955 RVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSP 990 V A+ ++G+ F A ELE+I P Sbjct: 157 LVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEP 192 Score = 45.1 bits (105), Expect = 0.001 Identities = 48/202 (23%), Positives = 84/202 (41%), Gaps = 31/202 (15%) Query: 2609 RRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQ 2668 +RA V D+ F+LD++ + F ++++++A LV ++ PD RV VV+ Sbjct: 28 QRAGCKSVHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDR------TRVGVVR 81 Query: 2669 HAPSESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFE 2728 ++ + F L +GS+E+ V +R + G G A+ Y F Sbjct: 82 YSDRPT----------TAFELGLFGSQEE-VKAAARRLAYHGGNTNTGDALRYITARSFS 130 Query: 2729 ----SAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVY 2784 P R K V ++LT + + +A +A G +G+G + +E+ Sbjct: 131 PHAGGRPRDRAYKQVAILLTDGRSQDLVLDAAAAAHRA---GIRIFAVGVGEALK-EELE 186 Query: 2785 TFASEPNDVF------FKLVDK 2800 ASEP F +DK Sbjct: 187 EIASEPKSAHVFHVSDFNAIDK 208 >gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens] Length = 1028 Score = 335 bits (859), Expect = 4e-91 Identities = 252/790 (31%), Positives = 359/790 (45%), Gaps = 72/790 (9%) Query: 2017 LAEQLDNIAEKACCGVPCK-CSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGP 2075 + + + N E+ CC C+ G G RG G G +G PG G +G GD G PG+ GP Sbjct: 235 IVDMIKNNVEQVCCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP 294 Query: 2076 PGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGR 2135 G QG +G G RG KGSRG G KGE G+ G+DG+DG G+ G PG G KG+PG Sbjct: 295 VGY---QGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGF 351 Query: 2136 RGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETG 2195 G +GP G KG+ G G++G+ G PG D G G G GP G G+ G PG PGE G Sbjct: 352 DGIQGPPGPKGDPGAFGLKGEKGEPGAD----GEAGRPGSSGPSGDEGQPGEPGPPGEKG 407 Query: 2196 KNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGG 2255 + G G GP GA G +GGPG E+G RG G GP G PG G QG G G G Sbjct: 408 EAGDEGNPGPDGAPGERGGPG------ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVG 461 Query: 2256 AAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGF 2315 G PGE G GP G +G+ G PG +G G GP G GD G G E G GF Sbjct: 462 VPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGF 521 Query: 2316 PGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPP----------GIVGQKGDPGYPGPAG 2365 PG+PG GN G PG+NGT G G++G G +G P G+ G KG G GP G Sbjct: 522 PGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQG 581 Query: 2366 PKGNRG-DSIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVNQDTFGRMRDV 2424 P G++G D+C ++ I C CC EC P +L F LD+SE + F +D Sbjct: 582 PPGHQGPPGPDECEILDIIMKMCSCC----ECKCGPIDLLFVLDSSESIGLQNFEIAKDF 637 Query: 2425 VLSIVNDLTIAE--SNCPRGARVAVVTYNNEVTTE---IRFADSKRKSVLLDKIKNLQVA 2479 V+ +++ L+ E P + VV Y++ E +R + L + IK+LQ Sbjct: 638 VVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQ-- 695 Query: 2480 LTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTRASP--QLREAVLKLSDAG 2537 + A+ + N + + S+T +P L +++ G Sbjct: 696 WMAGGTFTGEALQYTRDQLLPPSPNNRIALVITDGRSDTQRDTTPLNVLCSPGIQVVSVG 755 Query: 2538 ITPLFLTRQEDRQL----INALQINNTAVGHALVLPAGRDLTD--FLENVLTCHVCLDIC 2591 I +F QL L + G +LV +L + FL+NV T +C+D Sbjct: 756 IKDVFDFIPGSDQLNVISCQGLAPSQGRPGLSLVKENYAELLEDAFLKNV-TAQICIDKK 814 Query: 2592 NIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDM 2651 D +C P+ D+ +LD + + F+ K++ L + + Sbjct: 815 CPDYTCPITFSSPA-------------DITILLDGSASVGSHNFDTTKRFAKRLAERF-L 860 Query: 2652 SPDPKASQHFARVAVVQHAPS--ESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQL 2709 + H RVAVVQ++ + + + AS+ L +Y + VD M + Sbjct: 861 TAGRTDPAHDVRVAVVQYSGTGQQRPERASLQ------FLQNYTALASAVD----AMDFI 910 Query: 2710 QGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFF 2769 + A+ Y + + A + K ++L G ++ + +A+ G Sbjct: 911 NDATDVNDALGY-VTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQEAQRAGIEI 969 Query: 2770 VVLGIGRKVN 2779 V+ +GR+VN Sbjct: 970 FVVVVGRQVN 979 Score = 71.6 bits (174), Expect = 1e-11 Identities = 97/372 (26%), Positives = 141/372 (37%), Gaps = 54/372 (14%) Query: 445 DIVFLVDGSSALGLANFNAIRDFIAKVIQRL--------EIGQDLIQVAVAQYADTVRPE 496 D++F++D S ++GL NF +DF+ KVI RL E GQ V QY+ + E Sbjct: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQS--YAGVVQYSHSQMQE 672 Query: 497 FYFNTHPTKREVITAVRKMKPLDGSA--LYTGSALDFVRNNLFTSSAGYRAAEGIPKLLV 554 P+ R V +K L A +TG AL + R+ L S R A LV Sbjct: 673 HVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNRIA------LV 726 Query: 555 LITGGKSLDEISQPAQELKRSSIMAFAIGNK-------GADQAE------LEEIAFDSSL 601 + G + P L I ++G K G+DQ L L Sbjct: 727 ITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGL 786 Query: 602 VFIPAEFRAAPLQGMLPGLLAPLRTLSGTPE-----VHSNKRDIIFLLDGSANVGKTNFP 656 + + L + A + P+ S+ DI LLDGSA+VG NF Sbjct: 787 SLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHNFD 846 Query: 657 YVRDFVMNLVNS-LDIGN----DNIRVGLVQFSDT---PVTEFSLNTYQTKSDILGHLRQ 708 + F L L G ++RV +VQ+S T SL Q + + + Sbjct: 847 TTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASAVDA 906 Query: 709 LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSED----SYLQAAN 764 + + AL YV + EA ++ LLL + G S+ + +A Sbjct: 907 MDFI-NDATDVNDALGYV-TRFYREASSGAAKKR----LLLFSDGNSQGATPAAIEKAVQ 960 Query: 765 ALTRAGILTFCV 776 RAGI F V Sbjct: 961 EAQRAGIEIFVV 972 Score = 65.9 bits (159), Expect = 6e-10 Identities = 84/349 (24%), Positives = 147/349 (42%), Gaps = 45/349 (12%) Query: 39 DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGE------NDFHFALVQFNGN---PHT 89 D++F++DSS +IG ++F++ ++F+ V+ L+ E + +VQ++ + H Sbjct: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674 Query: 90 EFLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVL 149 + R QE+ I ++ ++ G TG+ L+Y L + +R + +V+ Sbjct: 675 SLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNR-------IALVI 727 Query: 150 TDGHSKDGL-ALPSAELKSADVNVFAIGVEDA-----DEGALKEIASEPLNMHM------ 197 TDG S P L S + V ++G++D L I+ + L Sbjct: 728 TDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLS 787 Query: 198 FNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVN 257 EN+ L + + V + + ++ T IT ADI L+DGS + GS N Sbjct: 788 LVKENYAEL--LEDAFLKNVTAQICIDKKCPDYTC-PITFSSPADITILLDGSASVGSHN 844 Query: 258 FAVILDFLVNLLEK-LPIG----TQQIRVGVVQFS---DEPRTMFSLDTYSTKAQVLGAV 309 F F L E+ L G +RV VVQ+S + SL + AV Sbjct: 845 FDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASAV 904 Query: 310 KALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPS 358 A+ F + ++ AL +V + + G+ + L+L S G S Sbjct: 905 DAMDFI-NDATDVNDALGYVTRFYREASSGAAKKR-----LLLFSDGNS 947 Score = 56.6 bits (135), Expect = 4e-07 Identities = 88/335 (26%), Positives = 135/335 (40%), Gaps = 60/335 (17%) Query: 837 DILFLFDGSANL-VGQFPVVRDFLYKIIDELN------VKPEGTRIAVAQYSDDVKVESR 889 D+LF+ D S ++ + F + +DF+ K+ID L+ +P + V QYS S+ Sbjct: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYS-----HSQ 669 Query: 890 FDEHQS--KPEILNL------VKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVL 941 EH S P I N+ +K ++ G G AL Y + + S +RI Sbjct: 670 MQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFT-GEALQYTRDQLLPPSPNNRIA---- 724 Query: 942 QFLVLLVAGRSSDRVDG-PASNLKQSGVVPFIFQAKNAD---PAELEQIVLSPAFILAAE 997 +++ GRS + D P + L G+ K+ P + V+S + ++ Sbjct: 725 ---LVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQ 781 Query: 998 SLPKIGDLHPQIVNLL----------------KSVHNGAPAPVSGEKDVVFLLDGSEGVR 1041 P + + LL K P S D+ LLDGS V Sbjct: 782 GRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASVG 841 Query: 1042 S-GFPLLKEFVQRVVESL------DVGQDRVRVAVVQYS--DRTRPE-FYLNSYMNKQDV 1091 S F K F +R+ E D D VRVAVVQYS + RPE L N + Sbjct: 842 SHNFDTTKRFAKRLAERFLTAGRTDPAHD-VRVAVVQYSGTGQQRPERASLQFLQNYTAL 900 Query: 1092 VNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGS 1126 +AV + + T + AL +V R +S+G+ Sbjct: 901 ASAVDAMDFINDAT-DVNDALGYVTRFYREASSGA 934 Score = 55.8 bits (133), Expect = 6e-07 Identities = 70/305 (22%), Positives = 124/305 (40%), Gaps = 44/305 (14%) Query: 1436 DIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLN------IGPSKVRVGVVQFSNDVFPE-- 1487 D++F++DSSE + F +DFV +++ RL+ P + GVVQ+S+ E Sbjct: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674 Query: 1488 -FYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVL 1546 + R+ + +AI+ L+ G TG+AL++ L S +RI LV+ Sbjct: 675 SLRSPSIRNVQELKEAIKSLQWMAGGTF-TGEALQYTRDQLLPPSPNNRIA------LVI 727 Query: 1547 VLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNI-----DRTELQTIT--------NDPRLV 1593 G + V+ S GI + VG +++ +L I+ P L Sbjct: 728 TDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLS 787 Query: 1594 FTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRD 1653 + EL +E+ + + T P + ADI LLDGS + Sbjct: 788 LVKENYAEL--LEDAFLKNVTAQICIDKKCPDYTCPIT--FSSPADITILLDGSASVGSH 843 Query: 1654 SFQEVLRFVSEIVDTVYEDG-----DSIQVGLVQYNS------DPTDEFFLKDFSTKRQI 1702 +F RF + + G ++V +VQY+ + FL++++ Sbjct: 844 NFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASA 903 Query: 1703 IDAIN 1707 +DA++ Sbjct: 904 VDAMD 908 Score = 52.8 bits (125), Expect = 5e-06 Identities = 89/373 (23%), Positives = 151/373 (40%), Gaps = 47/373 (12%) Query: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKL------PIGTQQIRVGVVQFS-DEPRTMF 294 D++F++D S + G NF + DF+V ++++L Q GVVQ+S + + Sbjct: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674 Query: 295 SLDTYSTK--AQVLGAVKALGF-AGGELANIGLALDFVVENHFTRAGGSRV--------- 342 SL + S + ++ A+K+L + AGG G AL + + + +R+ Sbjct: 675 SLRSPSIRNVQELKEAIKSLQWMAGGTFT--GEALQYTRDQLLPPSPNNRIALVITDGRS 732 Query: 343 --EEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVF 400 + + VL S G VV++ VF F G+ + Q +A Sbjct: 733 DTQRDTTPLNVLCSPG-------IQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPG 785 Query: 401 TVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLAN 460 ++ +L E V AQ I K P + + DI L+DGS+++G N Sbjct: 786 LSLVKENYAELLEDAFLKNV-TAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHN 844 Query: 461 FNAIRDFIAKVIQR-LEIGQ----DLIQVAVAQYADT--VRPEFYFNTHPTKREVITAVR 513 F+ + F ++ +R L G+ ++VAV QY+ T RPE + + Sbjct: 845 FDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASAV 904 Query: 514 KMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLD----EISQPA 569 A AL +V +S+G K L+L + G S I + Sbjct: 905 DAMDFINDATDVNDALGYVTRFYREASSG-----AAKKRLLLFSDGNSQGATPAAIEKAV 959 Query: 570 QELKRSSIMAFAI 582 QE +R+ I F + Sbjct: 960 QEAQRAGIEIFVV 972 Score = 50.8 bits (120), Expect = 2e-05 Identities = 89/358 (24%), Positives = 148/358 (41%), Gaps = 55/358 (15%) Query: 1230 GKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLD----VGFDTTR--VAVIQFSDDPKV 1282 G D++F++D S+S G + F+ + + +++D L V F+ + V+Q+S Sbjct: 612 GPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQ 671 Query: 1283 EFL-LNAHSSKD--EVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQF 1339 E + L + S ++ E++ A++ L+ G G AL+Y + +RI Sbjct: 672 EHVSLRSPSIRNVQELKEAIKSLQWMAGGTFT-GEALQYTRDQLLPPSPNNRIA------ 724 Query: 1340 LVLISSGKSDDEVD--------DPAVELKQFGVAP-FTIARNADQEELVKIS-LSPEYV- 1388 ++I+ G+SD + D P +++ G+ F +DQ ++ L+P Sbjct: 725 -LVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGR 783 Query: 1389 --FSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEG 1446 S+ LE L +T QI Y P S ADI L+D S Sbjct: 784 PGLSLVKENYAELLEDAFLKNVTA----QICIDKKCPDYTCPITFSSPADITILLDGSAS 839 Query: 1447 VRPDGFAHIRDFVSRIVRR-LNIGPS----KVRVGVVQFS--NDVFPE----FYLKTYRS 1495 V F + F R+ R L G + VRV VVQ+S PE +L+ Y + Sbjct: 840 VGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTA 899 Query: 1496 QAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQ 1553 A +DA+ + + AL +V R F + A S + L+L G SQ Sbjct: 900 LASAVDAMDFI----NDATDVNDALGYVTR--FYREASS---GAAKKRLLLFSDGNSQ 948 Score = 47.0 bits (110), Expect = 3e-04 Identities = 65/275 (23%), Positives = 112/275 (40%), Gaps = 42/275 (15%) Query: 639 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD------IGNDNIRVGLVQFSDTPVTE-F 691 D++F+LD S ++G NF +DFV+ +++ L G+VQ+S + + E Sbjct: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674 Query: 692 SLNTYQTKS--DILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLL 749 SL + ++ ++ ++ LQ G G TG AL Y + +RI L+ Sbjct: 675 SLRSPSIRNVQELKEAIKSLQWMAG-GTFTGEALQYTRDQLLPPSPNNRI-------ALV 726 Query: 750 LTAGQSEDSY-LQAANALTRAGI----------LTFCVGASQANKAELEQIA---FNPSL 795 +T G+S+ N L GI F G+ Q N + +A P L Sbjct: 727 ITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGL 786 Query: 796 VYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQP---ESKRDILFLFDGSANLVG-Q 851 + ++++ L L ++ +T + + P S DI L DGSA++ Sbjct: 787 SLVKENYAEL--LEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHN 844 Query: 852 FPVVRDFLYKIIDEL-----NVKPEGTRIAVAQYS 881 F + F ++ + R+AV QYS Sbjct: 845 FDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYS 879 Score = 44.7 bits (104), Expect = 0.001 Identities = 87/396 (21%), Positives = 160/396 (40%), Gaps = 46/396 (11%) Query: 1639 DIVFLLDGSINFRRDSFQEVLRFVSEIVDTV-------YEDGDSIQVGLVQY-NSDPTDE 1690 D++F+LD S + +F+ FV +++D + +E G S G+VQY +S + Sbjct: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQS-YAGVVQYSHSQMQEH 673 Query: 1691 FFLKDFSTK--RQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAF 1748 L+ S + +++ +AI + + G T L++ R P +R IA Sbjct: 674 VSLRSPSIRNVQELKEAIKSLQWMAG-GTFTGEALQYTRDQLLPPSPNNR-------IAL 725 Query: 1749 VITGGKSVEDAQDVSL-ALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQ---E 1804 VIT G+S L L G++V +VG++++ G N + + Q Sbjct: 726 VITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPG 785 Query: 1805 LSELSEQVLETLHDAMHETL---------CPGVT-DAAKACNLDVILGFDGSRDQNVFVA 1854 LS + E E L DA + + CP T + D+ + DGS V Sbjct: 786 LSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSAS----VG 841 Query: 1855 QKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVE----AFDFDEYQPEM 1910 F++ R+++ + + VRV+VV + +G + F + + Sbjct: 842 SHNFDT-TKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTAL 900 Query: 1911 LEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVKV-VIHFTDG--ADGDLADLHRASE 1967 M + D L +R++S + K ++ F+DG A + +A + Sbjct: 901 ASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQ 960 Query: 1968 NLRQEGVRALILVGLERVVNLERLMHLEFGRGFMYD 2003 ++ G+ ++V + R VN + L G+ YD Sbjct: 961 EAQRAGIEIFVVV-VGRQVNEPHIRVLVTGKTAEYD 995 Score = 40.0 bits (92), Expect = 0.037 Identities = 38/169 (22%), Positives = 75/169 (44%), Gaps = 20/169 (11%) Query: 2618 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2677 ID+ F+LDS+E+ L F K ++ ++ +L K + VVQ++ S+ ++ Sbjct: 614 IDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEH 673 Query: 2678 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLK 2737 S+ + + ++L + + + + + G G A++YT + + +PN R Sbjct: 674 VSLRSPSIR-------NVQELKEAI-KSLQWMAGGTFTGEALQYTRDQLLPPSPNNR--- 722 Query: 2738 IVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTF 2786 + L++T + Q + L C VV V IK+V+ F Sbjct: 723 -IALVITDGRSDTQRDTTP---LNVLCSPGIQVV-----SVGIKDVFDF 762 Score = 33.5 bits (75), Expect = 3.4 Identities = 33/154 (21%), Positives = 66/154 (42%), Gaps = 21/154 (13%) Query: 38 ADIIFLVDSSWTIGEEHFQLVREFLYDVV-KSLAVGE----NDFHFALVQFNGNPH---T 89 ADI L+D S ++G +F + F + + L G +D A+VQ++G Sbjct: 828 ADITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPE 887 Query: 90 EFLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVL 149 L + + S + M +I L Y+ + + ++G+ + +++ Sbjct: 888 RASLQFLQNYTALASAVDAMDFINDATDVNDALGYVTRFYREASSGA-----AKKRLLLF 942 Query: 150 TDGHSKDGLALPSA------ELKSADVNVFAIGV 177 +DG+S+ A P+A E + A + +F + V Sbjct: 943 SDGNSQG--ATPAAIEKAVQEAQRAGIEIFVVVV 974 >gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Homo sapiens] Length = 1019 Score = 325 bits (833), Expect = 4e-88 Identities = 251/776 (32%), Positives = 352/776 (45%), Gaps = 76/776 (9%) Query: 1935 NKFRQSSPDSVKVVIHF----TDG--ADGDLADLHRASENLRQEGVRALILVGLERVVNL 1988 N Q D K +HF TDG + +E R+EG+R L V + + Sbjct: 140 NMTEQIRQDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERAREEGIR-LFAVAPNQNLKE 198 Query: 1989 ERLMHLEFGRGFMYDRPLRLNLLD---LDYELAEQLDNIAEKACCGVPCKCSGQRGDRGP 2045 + L + +Y L D +D + ++ + + G K S GP Sbjct: 199 QGLRDIASTPHELYRNDYATMLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIP-GP 257 Query: 2046 IGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGF---QGCPGQRGVKGSRGFPGE 2102 G G +G G G G PG+ G G +G PG+ G GF +G PG +G KG G G Sbjct: 258 SGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGR 317 Query: 2103 KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKG---ERGDVGIRGDPGN 2159 KG G G +G DG+ G G G G KG+PG RG G GE G ERGD G +GDPG Sbjct: 318 KGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGR 377 Query: 2160 PGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPG 2219 PG+ RGP GE G G G G G PG PG G GG G RGP G G +G PG G Sbjct: 378 PGR----RGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKG 433 Query: 2220 FEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPG 2279 G G +G +G GP GP GL GE G G +G G G G +G G G++G G+PG Sbjct: 434 SPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPG 493 Query: 2280 PKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGI 2339 G G+ G G GD GR G G RG GE+G PG GP+G G+ GL G G KG Sbjct: 494 DAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGE 553 Query: 2340 RGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD-SIDQCALIQSIKDKCPCCYGPLECPV 2398 +G + GPPG G +G G PGP G G GD + +C ++ +++ C CC C Sbjct: 554 KGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKRCGA 613 Query: 2399 FPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDL--TIAESNCPRGARVAVVTYNNEVTT 2456 ++ F +D+SE + F ++ V+++VN L + G RV VV Y++E T Sbjct: 614 L--DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTF 671 Query: 2457 EIRFADSKR---KSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAV 2513 E D +R S + +KNL+ + +A+ F K R +K V Sbjct: 672 EAIQLDDERIDSLSSFKEAVKNLE--WIAGGTWTPSALKFAYDRLIKESRR----QKTRV 725 Query: 2514 F-FSNTPTRASPQ--------LREAVLKLSDAGITPLFLTRQEDRQLINAL-----QINN 2559 F T R P+ L + + ++ GI +F + E L + Q+ N Sbjct: 726 FAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKPQQVRN 785 Query: 2560 TAVGHALVLPAGRDLTDFLENVLTCH---VCLDI-CNIDPSCGFGSWRPSFRDRRAAGSD 2615 + LV D +E+VL VC D+ C + S + RP Sbjct: 786 MTLFSDLV---AEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRP----------- 831 Query: 2616 VDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMS---PDPKASQHFARVAVVQ 2668 +D+ F+LD +E F++ ++++ + R+L ++ DP ARVA++Q Sbjct: 832 --VDIVFLLDGSERLGEQNFHKARRFVEQVARRLTLARRDDDPLN----ARVALLQ 881 Score = 65.1 bits (157), Expect = 1e-09 Identities = 88/361 (24%), Positives = 154/361 (42%), Gaps = 48/361 (13%) Query: 1434 AADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNI------GPSKVRVGVVQFSND-VFP 1486 A D+VF+IDSSE + F ++FV +V RL + RVGVVQ+S++ F Sbjct: 613 ALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFE 672 Query: 1487 EFYLKTYR--SQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHL 1544 L R S + +A++ L G T AL+F L +S + Sbjct: 673 AIQLDDERIDSLSSFKEAVKNLEWIAGGTW-TPSALKFAYDRLIKESRRQKTR----VFA 727 Query: 1545 VLVLGGKSQ---DDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTI----TNDPRLVFTVR 1597 V++ G+ DD++ A R + ++G+GD ++ E + + + P+ V + Sbjct: 728 VVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKPQQVRNMT 787 Query: 1598 EFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPE-------KKKADIVFLLDGSINF 1650 F +L + E+ ++ P P V P + E ++ DIVFLLDGS Sbjct: 788 LFSDL--VAEKFIDDM-EDVLCPDPQIVCPDLPCQTELSVAQCTQRPVDIVFLLDGSERL 844 Query: 1651 RRDSFQEVLRFVSEIVDTVY-----EDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDA 1705 +F + RFV ++ + +D + +V L+Q+ + I +A Sbjct: 845 GEQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQVAFPLSHNLTAIHEA 904 Query: 1706 INKVVYKGGRHANTKVGLEHLRVNHFV--PEAGSRLDQRVPQIAFV-----ITGGKSVED 1758 + Y ++ G+ H +N V P G+R R +++FV +TG S+ + Sbjct: 905 LETTQYLNS-FSHVGAGVVH-AINAIVRSPRGGAR---RHAELSFVFLTDGVTGNDSLHE 959 Query: 1759 A 1759 + Sbjct: 960 S 960 Score = 60.5 bits (145), Expect = 3e-08 Identities = 91/368 (24%), Positives = 156/368 (42%), Gaps = 43/368 (11%) Query: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKL------PIGTQQIRVGVVQFSDEPRTMFS 295 D++F+ID S + G NF + +F++N++ +L P RVGVVQ+S E T + Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEG-TFEA 673 Query: 296 LDTYSTKAQVLG----AVKALGF-AGGELANIGL--ALDFVVENHFTRAGGSRVEEGVPQ 348 + + L AVK L + AGG L A D +++ +R +RV Sbjct: 674 IQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKE--SRRQKTRV------ 725 Query: 349 VLVLISAG---PSSDEIRYGVVALKQASVFSFGLGAQAASRAE---LQHIATDDNLVFTV 402 V+I+ G P D++ + + +V + G+G + E L IA D V Sbjct: 726 FAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKPQ--QV 783 Query: 403 PEFRSFGDL-QEKLLPYIVGVAQRHIVLKPPTIVTQ----VIEVNKR--DIVFLVDGSSA 455 F DL EK + + V + P + Q V + +R DIVFL+DGS Sbjct: 784 RNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRPVDIVFLLDGSER 843 Query: 456 LGLANFNAIRDFIAKVIQRLEIGQD-----LIQVAVAQYADTVRPEFYFNTHPTKREVIT 510 LG NF+ R F+ +V +RL + + +VA+ Q+ + F + Sbjct: 844 LGEQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQVAFPLSHNLTAIHE 903 Query: 511 AVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQ 570 A+ + L+ S + G+ + N + S G + L G D + + A Sbjct: 904 ALETTQYLN-SFSHVGAGVVHAINAIVRSPRGGARRHAELSFVFLTDGVTGNDSLHESAH 962 Query: 571 ELKRSSIM 578 +++ +++ Sbjct: 963 SMRKQNVV 970 Score = 56.6 bits (135), Expect = 4e-07 Identities = 69/278 (24%), Positives = 113/278 (40%), Gaps = 28/278 (10%) Query: 33 KNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAV------GENDFHFALVQFNGN 86 K A D++F++DSS +IG +F L + F+ +VV L E +VQ++ Sbjct: 609 KRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHE 668 Query: 87 PHTEFL-LNTYR--TKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVP 143 E + L+ R + + N+ +I G T L++ + ++ + Sbjct: 669 GTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQK----TR 724 Query: 144 QVIVVLTDG-HSKDGLALPSAELKSADVNVFAIGVEDA-----DEGALKEIA----SEPL 193 VV+TDG H L L DV V AIG+ D + L IA + Sbjct: 725 VFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKPQQVR 784 Query: 194 NMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNT 253 NM +F+ D + +++ V P+ TE Q DI+FL+DGS Sbjct: 785 NMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRPVDIVFLLDGSERL 844 Query: 254 GSVNFAVILDFLVNLLEKLPIGTQ-----QIRVGVVQF 286 G NF F+ + +L + + RV ++QF Sbjct: 845 GEQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQF 882 Score = 52.8 bits (125), Expect = 5e-06 Identities = 90/370 (24%), Positives = 149/370 (40%), Gaps = 56/370 (15%) Query: 445 DIVFLVDGSSALGLANFNAIRDFIAKVIQRL-EIGQDL-----IQVAVAQYADTVRPEFY 498 D+VF++D S ++G NF ++F+ V+ RL I +D +V V QY+ E Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSH----EGT 670 Query: 499 FNTHPTKREVIT-------AVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPK 551 F E I AV+ ++ + G +T SAL F + L S + Sbjct: 671 FEAIQLDDERIDSLSSFKEAVKNLEWIAGGT-WTPSALKFAYDRLIKESRRQKTRV---- 725 Query: 552 LLVLITGGKSL---DEISQPAQELKRSSIMAFAIGNKGADQAELEE---IAFD------- 598 V+IT G+ D+++ A + ++ A IG+ ++ E E IA D Sbjct: 726 FAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKPQQVRN 785 Query: 599 ----SSLVFIPAEFRAAPLQGML---PGLLAP---LRTLSGTPEVHSNKRDIIFLLDGSA 648 S LV AE ++ +L P ++ P +T + DI+FLLDGS Sbjct: 786 MTLFSDLV---AEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRPVDIVFLLDGSE 842 Query: 649 NVGKTNFPYVRDFVMNLVNSLDIGND-----NIRVGLVQFSDTPVTEFSLNTYQTKSDIL 703 +G+ NF R FV + L + N RV L+QF + + + I Sbjct: 843 RLGEQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQVAFPLSHNLTAIH 902 Query: 704 GHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAG-QSEDSYLQA 762 L Q + + A + GG+ R H + LT G DS ++ Sbjct: 903 EALETTQYLNSFSHVGAGVVHAINAIVRSPRGGA--RRHAELSFVFLTDGVTGNDSLHES 960 Query: 763 ANALTRAGIL 772 A+++ + ++ Sbjct: 961 AHSMRKQNVV 970 Score = 50.8 bits (120), Expect = 2e-05 Identities = 89/385 (23%), Positives = 153/385 (39%), Gaps = 33/385 (8%) Query: 1026 GEKDVVFLLDGSEGVR-SGFPLLKEFVQRVVESLDV------GQDRVRVAVVQYS-DRTR 1077 G DVVF++D SE + + F L K FV VV L + RV VVQYS + T Sbjct: 612 GALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTF 671 Query: 1078 PEFYLNSYM--NKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQL 1135 L+ + AV+ L + G T T +AL+F ++ S + Sbjct: 672 EAIQLDDERIDSLSSFKEAVKNLEWIAGGTW-TPSALKFAYDRLIKESRRQKTRV----F 726 Query: 1136 LIVLTADRSG--DDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQ 1193 +V+T R DD N + R V IGIG+ + ++ + R Sbjct: 727 AVVITDGRHDPRDDDLNLRALCDRDVTVT-AIGIGDMFHEKHESENLYSIACDKPQQVRN 785 Query: 1194 LGTVQQVISERVTQLTREELSRLQPVLQP-LP-----SPGVGGKR--DVVFLIDGSQSAG 1245 + +++E+ + L ++ P LP S +R D+VFL+DGS+ G Sbjct: 786 MTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRPVDIVFLLDGSERLG 845 Query: 1246 PE-FQYVRTLIERLVDYLDVGFD-----TTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAV 1299 + F R +E++ L + RVA++QF + + + + A+ Sbjct: 846 EQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQVAFPLSHNLTAIHEAL 905 Query: 1300 QRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVEL 1359 + + +VG + + I + P G F+ L +D + + A + Sbjct: 906 ETTQYLNSFS-HVGAGVVHAINAIVRSPRGGARRHAELSFVFLTDGVTGNDSLHESAHSM 964 Query: 1360 KQFGVAPFTIARNADQEELVKISLS 1384 ++ V P +A +D + V +LS Sbjct: 965 RKQNVVPTVLALGSDVDMDVLTTLS 989 Score = 50.8 bits (120), Expect = 2e-05 Identities = 87/366 (23%), Positives = 150/366 (40%), Gaps = 39/366 (10%) Query: 639 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD-IGND-----NIRVGLVQFSDTPVTEFS 692 D++F++D S ++G TNF ++FV+N+VN L I D RVG+VQ+S E + Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFE-A 673 Query: 693 LNTYQTKSDILGHLRQ----LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLL 748 + + D L ++ L+ G G T SAL + Y E+ R+ + Sbjct: 674 IQLDDERIDSLSSFKEAVKNLEWIAG-GTWTPSALKFAYDRLIKESR----RQKTRVFAV 728 Query: 749 LLTAGQSE--DSYLQAANALTR-AGILTFCVGASQANKAELEQI----AFNPSLVYLMDD 801 ++T G+ + D L R + +G K E E + P V M Sbjct: 729 VITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKPQQVRNMTL 788 Query: 802 FSSLPALP-----QQLIQPLTTYVSGGV---EEVPLAQ-PESKRDILFLFDGSANLVGQ- 851 FS L A + ++ P V + E+ +AQ + DI+FL DGS L Q Sbjct: 789 FSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRPVDIVFLLDGSERLGEQN 848 Query: 852 FPVVRDFLYKIIDELNV-----KPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRM 906 F R F+ ++ L + P R+A+ Q+ + + F + I ++ Sbjct: 849 FHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQVAFPLSHNLTAIHEALETT 908 Query: 907 KIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQS 966 + + ++G + +A I G L F+ L +D + A ++++ Sbjct: 909 QYLNSFS-HVGAGVVHAINAIVRSPRGGARRHAELSFVFLTDGVTGNDSLHESAHSMRKQ 967 Query: 967 GVVPFI 972 VVP + Sbjct: 968 NVVPTV 973 Score = 50.4 bits (119), Expect = 3e-05 Identities = 67/276 (24%), Positives = 112/276 (40%), Gaps = 30/276 (10%) Query: 1230 GKRDVVFLIDGSQSAG-PEFQYVRTLIERLVDYL-----DVGFDT-TRVAVIQFSDDPKV 1282 G DVVF+ID S+S G F + + +V+ L D +T TRV V+Q+S + Sbjct: 612 GALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTF 671 Query: 1283 EFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVL 1342 E + D + + + + K I G + + R + + F V+ Sbjct: 672 EAIQLDDERIDSLSSFKEAV--KNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVFAVV 729 Query: 1343 ISSGKSDDEVDD--------PAVELKQFGVAPFTIARNADQEELVKISLS-PEYVFSVST 1393 I+ G+ D DD V + G+ ++ + E L I+ P+ V +++ Sbjct: 730 ITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKH-ESENLYSIACDKPQQVRNMTL 788 Query: 1394 FRELPSLEQKLLTPITTLTSEQIQ----KLLASTRYPPPAVESDAADIVFLIDSSEGVRP 1449 F +L + +K + + + Q L T DIVFL+D SE + Sbjct: 789 FSDL--VAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRPVDIVFLLDGSERLGE 846 Query: 1450 DGFAHIRDFVSRIVRRLNIG-----PSKVRVGVVQF 1480 F R FV ++ RRL + P RV ++QF Sbjct: 847 QNFHKARRFVEQVARRLTLARRDDDPLNARVALLQF 882 Score = 42.0 bits (97), Expect = 0.010 Identities = 38/159 (23%), Positives = 64/159 (40%), Gaps = 10/159 (6%) Query: 39 DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGEND-----FHFALVQFNGNPHTEFLL 93 DI+FL+D S +GE++F R F+ V + L + D AL+QF G + Sbjct: 833 DIVFLLDGSERLGEQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQVAF 892 Query: 94 NTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDG- 152 + + Y+ + G G+ + + + + G A V LTDG Sbjct: 893 PLSHNLTAIHEALETTQYLNSFSHVGAGVVHAINAIVRSPRGG-ARRHAELSFVFLTDGV 951 Query: 153 HSKDGLALPSAELKSADV--NVFAIGVEDADEGALKEIA 189 D L + ++ +V V A+G D D L ++ Sbjct: 952 TGNDSLHESAHSMRKQNVVPTVLALG-SDVDMDVLTTLS 989 Score = 34.7 bits (78), Expect = 1.5 Identities = 22/89 (24%), Positives = 50/89 (56%), Gaps = 3/89 (3%) Query: 2618 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLD-MSPDPKASQHFARVAVVQHAPSESVD 2676 +D+ F++DS+E+ F K ++ +V +L ++ DPK S+ RV VVQ++ + + Sbjct: 614 LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPK-SETGTRVGVVQYSHEGTFE 672 Query: 2677 NASMPPVKVEFSLTDYGSKEKLVDFLSRG 2705 + +++ SL+ + K +++++ G Sbjct: 673 AIQLDDERID-SLSSFKEAVKNLEWIAGG 700 >gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [Homo sapiens] Length = 828 Score = 317 bits (812), Expect = 1e-85 Identities = 205/564 (36%), Positives = 271/564 (48%), Gaps = 29/564 (5%) Query: 1935 NKFRQSSPDSVKVVIHF----TDG--ADGDLADLHRASENLRQEGVRALILVGLERVVNL 1988 N Q D K +HF TDG + +E R+EG+R L V + + Sbjct: 140 NMTEQIRQDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERAREEGIR-LFAVAPNQNLKE 198 Query: 1989 ERLMHLEFGRGFMYDRPLRLNLLD---LDYELAEQLDNIAEKACCGVPCKCSGQRGDRGP 2045 + L + +Y L D +D + ++ + + G K S GP Sbjct: 199 QGLRDIASTPHELYRNDYATMLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIP-GP 257 Query: 2046 IGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGF---QGCPGQRGVKGSRGFPGE 2102 G G +G G G G PG+ G G +G PG+ G GF +G PG +G KG G G Sbjct: 258 SGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGR 317 Query: 2103 KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKG---ERGDVGIRGDPGN 2159 KG G G +G DG+ G G G G KG+PG RG G GE G ERGD G +GDPG Sbjct: 318 KGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGR 377 Query: 2160 PGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPG 2219 PG+ RGP GE G G G G G PG PG G GG G RGP G G +G PG G Sbjct: 378 PGR----RGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKG 433 Query: 2220 FEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPG 2279 G G +G +G GP GP GL GE G G +G G G G +G G G++G G+PG Sbjct: 434 SPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPG 493 Query: 2280 PKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGI 2339 G G+ G G GD GR G G RG GE+G PG GP+G G+ GL G G KG Sbjct: 494 DAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGE 553 Query: 2340 RGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD-SIDQCALIQSIKDKCPCCYGPLECPV 2398 +G + GPPG G +G G PGP G G GD + +C ++ +++ C CC C Sbjct: 554 KGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKRCGA 613 Query: 2399 FPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDL--TIAESNCPRGARVAVVTYNNEVTT 2456 ++ F +D+SE + F ++ V+++VN L + G RV VV Y++E T Sbjct: 614 L--DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTF 671 Query: 2457 EIRFADSKR---KSVLLDKIKNLQ 2477 E D +R S + +KNL+ Sbjct: 672 EAIQLDDERIDSLSSFKEAVKNLE 695 Score = 45.8 bits (107), Expect = 7e-04 Identities = 45/165 (27%), Positives = 75/165 (45%), Gaps = 17/165 (10%) Query: 1434 AADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNI------GPSKVRVGVVQFSND-VFP 1486 A D+VF+IDSSE + F ++FV +V RL + RVGVVQ+S++ F Sbjct: 613 ALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFE 672 Query: 1487 EFYLKTYR--SQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHL 1544 L R S + +A++ L G T AL+F L +S + Sbjct: 673 AIQLDDERIDSLSSFKEAVKNLEWIAGGTW-TPSALKFAYDRLIKESRRQKTR----VFA 727 Query: 1545 VLVLGGK---SQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTI 1586 V++ G+ DD++ A R + ++G+GD ++ E + + Sbjct: 728 VVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENL 772 Score = 43.5 bits (101), Expect = 0.003 Identities = 35/112 (31%), Positives = 56/112 (50%), Gaps = 12/112 (10%) Query: 639 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD-IGND-----NIRVGLVQFSDTPVTEFS 692 D++F++D S ++G TNF ++FV+N+VN L I D RVG+VQ+S E + Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFE-A 673 Query: 693 LNTYQTKSDILGHLRQ----LQLQGGSGLNTGSALSYVYANHFTEAGGSRIR 740 + + D L ++ L+ G G T SAL + Y E+ + R Sbjct: 674 IQLDDERIDSLSSFKEAVKNLEWIAG-GTWTPSALKFAYDRLIKESRRQKTR 724 Score = 40.8 bits (94), Expect = 0.022 Identities = 41/157 (26%), Positives = 67/157 (42%), Gaps = 14/157 (8%) Query: 33 KNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAV------GENDFHFALVQFNGN 86 K A D++F++DSS +IG +F L + F+ +VV L E +VQ++ Sbjct: 609 KRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHE 668 Query: 87 PHTEFL-LNTYR--TKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVP 143 E + L+ R + + N+ +I G T L++ + ++ + Sbjct: 669 GTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQK----TR 724 Query: 144 QVIVVLTDG-HSKDGLALPSAELKSADVNVFAIGVED 179 VV+TDG H L L DV V AIG+ D Sbjct: 725 VFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGD 761 Score = 39.7 bits (91), Expect = 0.048 Identities = 20/54 (37%), Positives = 32/54 (59%), Gaps = 6/54 (11%) Query: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKL------PIGTQQIRVGVVQFSDE 289 D++F+ID S + G NF + +F++N++ +L P RVGVVQ+S E Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHE 668 Score = 35.0 bits (79), Expect = 1.2 Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 25/167 (14%) Query: 445 DIVFLVDGSSALGLANFNAIRDFIAKVIQRL-EIGQDL-----IQVAVAQYADTVRPEFY 498 D+VF++D S ++G NF ++F+ V+ RL I +D +V V QY+ E Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSH----EGT 670 Query: 499 FNTHPTKREVI-------TAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPK 551 F E I AV+ ++ + G +T SAL F + L S + Sbjct: 671 FEAIQLDDERIDSLSSFKEAVKNLEWIAGGT-WTPSALKFAYDRLIKESRRQKTR----V 725 Query: 552 LLVLITGGK---SLDEISQPAQELKRSSIMAFAIGNKGADQAELEEI 595 V+IT G+ D+++ A + ++ A IG+ ++ E E + Sbjct: 726 FAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENL 772 Score = 34.7 bits (78), Expect = 1.5 Identities = 22/89 (24%), Positives = 50/89 (56%), Gaps = 3/89 (3%) Query: 2618 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLD-MSPDPKASQHFARVAVVQHAPSESVD 2676 +D+ F++DS+E+ F K ++ +V +L ++ DPK S+ RV VVQ++ + + Sbjct: 614 LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPK-SETGTRVGVVQYSHEGTFE 672 Query: 2677 NASMPPVKVEFSLTDYGSKEKLVDFLSRG 2705 + +++ SL+ + K +++++ G Sbjct: 673 AIQLDDERID-SLSSFKEAVKNLEWIAGG 700 >gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Homo sapiens] Length = 918 Score = 317 bits (812), Expect = 1e-85 Identities = 205/564 (36%), Positives = 271/564 (48%), Gaps = 29/564 (5%) Query: 1935 NKFRQSSPDSVKVVIHF----TDG--ADGDLADLHRASENLRQEGVRALILVGLERVVNL 1988 N Q D K +HF TDG + +E R+EG+R L V + + Sbjct: 140 NMTEQIRQDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERAREEGIR-LFAVAPNQNLKE 198 Query: 1989 ERLMHLEFGRGFMYDRPLRLNLLD---LDYELAEQLDNIAEKACCGVPCKCSGQRGDRGP 2045 + L + +Y L D +D + ++ + + G K S GP Sbjct: 199 QGLRDIASTPHELYRNDYATMLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIP-GP 257 Query: 2046 IGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGF---QGCPGQRGVKGSRGFPGE 2102 G G +G G G G PG+ G G +G PG+ G GF +G PG +G KG G G Sbjct: 258 SGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGR 317 Query: 2103 KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKG---ERGDVGIRGDPGN 2159 KG G G +G DG+ G G G G KG+PG RG G GE G ERGD G +GDPG Sbjct: 318 KGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGR 377 Query: 2160 PGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPG 2219 PG+ RGP GE G G G G G PG PG G GG G RGP G G +G PG G Sbjct: 378 PGR----RGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKG 433 Query: 2220 FEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPG 2279 G G +G +G GP GP GL GE G G +G G G G +G G G++G G+PG Sbjct: 434 SPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPG 493 Query: 2280 PKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGI 2339 G G+ G G GD GR G G RG GE+G PG GP+G G+ GL G G KG Sbjct: 494 DAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGE 553 Query: 2340 RGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD-SIDQCALIQSIKDKCPCCYGPLECPV 2398 +G + GPPG G +G G PGP G G GD + +C ++ +++ C CC C Sbjct: 554 KGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKRCGA 613 Query: 2399 FPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDL--TIAESNCPRGARVAVVTYNNEVTT 2456 ++ F +D+SE + F ++ V+++VN L + G RV VV Y++E T Sbjct: 614 L--DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTF 671 Query: 2457 EIRFADSKR---KSVLLDKIKNLQ 2477 E D +R S + +KNL+ Sbjct: 672 EAIQLDDERIDSLSSFKEAVKNLE 695 Score = 45.8 bits (107), Expect = 7e-04 Identities = 45/165 (27%), Positives = 75/165 (45%), Gaps = 17/165 (10%) Query: 1434 AADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNI------GPSKVRVGVVQFSND-VFP 1486 A D+VF+IDSSE + F ++FV +V RL + RVGVVQ+S++ F Sbjct: 613 ALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFE 672 Query: 1487 EFYLKTYR--SQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHL 1544 L R S + +A++ L G T AL+F L +S + Sbjct: 673 AIQLDDERIDSLSSFKEAVKNLEWIAGGTW-TPSALKFAYDRLIKESRRQKTR----VFA 727 Query: 1545 VLVLGGK---SQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTI 1586 V++ G+ DD++ A R + ++G+GD ++ E + + Sbjct: 728 VVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENL 772 Score = 43.5 bits (101), Expect = 0.003 Identities = 35/112 (31%), Positives = 56/112 (50%), Gaps = 12/112 (10%) Query: 639 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD-IGND-----NIRVGLVQFSDTPVTEFS 692 D++F++D S ++G TNF ++FV+N+VN L I D RVG+VQ+S E + Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFE-A 673 Query: 693 LNTYQTKSDILGHLRQ----LQLQGGSGLNTGSALSYVYANHFTEAGGSRIR 740 + + D L ++ L+ G G T SAL + Y E+ + R Sbjct: 674 IQLDDERIDSLSSFKEAVKNLEWIAG-GTWTPSALKFAYDRLIKESRRQKTR 724 Score = 40.8 bits (94), Expect = 0.022 Identities = 41/157 (26%), Positives = 67/157 (42%), Gaps = 14/157 (8%) Query: 33 KNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAV------GENDFHFALVQFNGN 86 K A D++F++DSS +IG +F L + F+ +VV L E +VQ++ Sbjct: 609 KRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHE 668 Query: 87 PHTEFL-LNTYR--TKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVP 143 E + L+ R + + N+ +I G T L++ + ++ + Sbjct: 669 GTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQK----TR 724 Query: 144 QVIVVLTDG-HSKDGLALPSAELKSADVNVFAIGVED 179 VV+TDG H L L DV V AIG+ D Sbjct: 725 VFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGD 761 Score = 39.7 bits (91), Expect = 0.048 Identities = 20/54 (37%), Positives = 32/54 (59%), Gaps = 6/54 (11%) Query: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKL------PIGTQQIRVGVVQFSDE 289 D++F+ID S + G NF + +F++N++ +L P RVGVVQ+S E Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHE 668 Score = 35.0 bits (79), Expect = 1.2 Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 25/167 (14%) Query: 445 DIVFLVDGSSALGLANFNAIRDFIAKVIQRL-EIGQDL-----IQVAVAQYADTVRPEFY 498 D+VF++D S ++G NF ++F+ V+ RL I +D +V V QY+ E Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSH----EGT 670 Query: 499 FNTHPTKREVI-------TAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPK 551 F E I AV+ ++ + G +T SAL F + L S + Sbjct: 671 FEAIQLDDERIDSLSSFKEAVKNLEWIAGGT-WTPSALKFAYDRLIKESRRQKTR----V 725 Query: 552 LLVLITGGK---SLDEISQPAQELKRSSIMAFAIGNKGADQAELEEI 595 V+IT G+ D+++ A + ++ A IG+ ++ E E + Sbjct: 726 FAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENL 772 Score = 34.7 bits (78), Expect = 1.5 Identities = 22/89 (24%), Positives = 50/89 (56%), Gaps = 3/89 (3%) Query: 2618 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLD-MSPDPKASQHFARVAVVQHAPSESVD 2676 +D+ F++DS+E+ F K ++ +V +L ++ DPK S+ RV VVQ++ + + Sbjct: 614 LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPK-SETGTRVGVVQYSHEGTFE 672 Query: 2677 NASMPPVKVEFSLTDYGSKEKLVDFLSRG 2705 + +++ SL+ + K +++++ G Sbjct: 673 AIQLDDERID-SLSSFKEAVKNLEWIAGG 700 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 307 bits (787), Expect = 9e-83 Identities = 170/372 (45%), Positives = 205/372 (55%), Gaps = 33/372 (8%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGE---DGYRGYPGDEGGPGERGPPGVNGTQGFQGCPG 2089 P +G+RG++GP GS G +G+PG G G PG++G PG+ G PG +G +G +G PG Sbjct: 624 PAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPG 683 Query: 2090 QRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGE---KGNPGRRGDKGPRGEKG 2146 +RGV+G G G +G G G DG G+ G G PGS G +G PG RG G G KG Sbjct: 684 ERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKG 743 Query: 2147 ERGDVGIRGDPGNPGQDSQER--------------GPKGETGDLGPMGVPGRDGVPGGPG 2192 +RGD G +G G+PG+D G KGE+G GP G G G PG G Sbjct: 744 DRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRG 803 Query: 2193 ETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRG 2252 E G G G GPPGA G G G+PG G +G G GPAGPAGPPG IG G G +G Sbjct: 804 EPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKG 863 Query: 2253 SGGAAGAPGER---------GRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VG 2302 + G+AG PG G GP G G PG PGP G G +GPRGETG GR G VG Sbjct: 864 ARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVG 923 Query: 2303 SEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGI---RGRRGNSGPPGIVGQKGDPG 2359 G G GE+G PG GP G PG PG G G +G+ G+RG G PG+ G G+PG Sbjct: 924 PPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPG 983 Query: 2360 YPGPAGPKGNRG 2371 GP+G G RG Sbjct: 984 KQGPSGASGERG 995 Score = 280 bits (715), Expect = 2e-74 Identities = 166/372 (44%), Positives = 186/372 (50%), Gaps = 33/372 (8%) Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPG---VNGTQ 2082 E+ G+P G +GDRG G G G PG+DG RG G G PG G PG +G Sbjct: 732 ERGAAGLP----GPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPS 787 Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142 G G G RG G RG PG G G G G DG+ G KG PG +G KG+ G G GP Sbjct: 788 GPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPA 847 Query: 2143 GEKGERGDVGI------RGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGK 2196 G G G+VG RG G PG G G G +GP G G G PG PG GK Sbjct: 848 GPPGPIGNVGAPGAKGARGSAGPPGAT----GFPGAAGRVGPPGPSGNAGPPGPPGPAGK 903 Query: 2197 NGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGA 2256 GG G RG G G G G PG G G +G+ G GPAG PG G QGI+G RG G Sbjct: 904 EGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGL 963 Query: 2257 AGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGP---------RGETGDDGRDGV------ 2301 G GERG G G GEPG+ GP G G RGP G G+ GR+G Sbjct: 964 PGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGS 1023 Query: 2302 -GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGY 2360 G +G G KG+RG G GP G PG PG G GP G G RG +GP G G G G Sbjct: 1024 PGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGA 1083 Query: 2361 PGPAGPKGNRGD 2372 GPAGP+G RGD Sbjct: 1084 RGPAGPQGPRGD 1095 Score = 277 bits (708), Expect = 1e-73 Identities = 158/349 (45%), Positives = 183/349 (52%), Gaps = 18/349 (5%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096 +G +GD GP G GP G PG G G PG +G G GPPG G G G G G G+ Sbjct: 832 AGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGN 891 Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGD 2156 G PG G G+ G G GE G G PG G G PG P GEKG G G G Sbjct: 892 AGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPG------PAGEKGSPGADGPAGA 945 Query: 2157 PGNPGQD--SQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGG 2214 PG PG + +RG G G G G PG G G PG+ G +G G RGPPG G G Sbjct: 946 PGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGL 1005 Query: 2215 PGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGE 2274 G PG G +G GA+G G G PG G++G +GP G GA GAPG G GP G+ G+ Sbjct: 1006 AGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGD 1065 Query: 2275 PGEPGPKGG------IGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGY---PGPKGN 2324 GE GP G +G RGP G G G G G +G RG KG RGF G PGP G+ Sbjct: 1066 RGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGS 1125 Query: 2325 PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373 PGE G +G +GP G RG G++G PG G G PG GP GP+G GD+ Sbjct: 1126 PGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDA 1174 Score = 273 bits (699), Expect = 2e-72 Identities = 155/350 (44%), Positives = 185/350 (52%), Gaps = 15/350 (4%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096 +G +G+ GP+G GP G GE+G RG G+ G G GPPG G G +G PG GV G Sbjct: 445 TGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGP 504 Query: 2097 RGFPGEKGEVGEIGLDGLDGE---DGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI 2153 +G GE+G G G G GE G+ GLPG+ G G+PG G G G G G G Sbjct: 505 KGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGR 564 Query: 2154 RGDPGNPGQDSQER-----GPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208 G PG PG Q GPKG G+ G G G G PG G GK+G G +GPPG Sbjct: 565 PGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGP 624 Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2268 G G G+ G G G +G GPAGP G G GEQG+ G G+ G +GA GERG G Sbjct: 625 AGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGE 684 Query: 2269 LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV----GSEGRRGKKGERGFPGYPGPKGN 2324 G +G PG GP+G G G G GD G G G+ G +G GERG G PGPKG+ Sbjct: 685 RGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGD 744 Query: 2325 PGE---PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 G+ G +G+ G G+RG G GPPG G GD G GP+GP G G Sbjct: 745 RGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTG 794 Score = 273 bits (698), Expect = 2e-72 Identities = 176/410 (42%), Positives = 197/410 (48%), Gaps = 64/410 (15%) Query: 2026 EKACCGV----PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGER---GPPGV 2078 EK+ G+ P SG RG GP G+ GP+G G G G PG G G R GPPG Sbjct: 169 EKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGK 228 Query: 2079 NGTQGFQGCPGQ------------RGVKGSRGFPGEKGEVGEIGLDGLDGE---DGDKGL 2123 NG G G PG+ RG+ G+ G PG KG G GLDG G+ G KG Sbjct: 229 NGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGE 288 Query: 2124 PGSSGEKGNPGRRGDKGPRGEKGE---------RGDVGIRGDPGNPGQDSQ--------- 2165 PGS GE G PG+ G +G GE+G RG+ G G G PG Sbjct: 289 PGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGA 348 Query: 2166 -----ERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGP---GQ 2217 E GP+G G GP GV G G PG G G G G G PGAKG G P G Sbjct: 349 VGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGA 408 Query: 2218 PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP------LGR 2271 PGF G +G G QGP GP GP G GE G G +G GA G PG G GP G+ Sbjct: 409 PGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGK 468 Query: 2272 KGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGE--- 2327 +G GEPGP G G G RG G G G G G +G GERG PG GPKG+PGE Sbjct: 469 RGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGR 528 Query: 2328 ------PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 PG G TG G G G +GPPG GQ G PG PGP G +G G Sbjct: 529 PGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAG 578 Score = 272 bits (696), Expect = 3e-72 Identities = 163/392 (41%), Positives = 194/392 (49%), Gaps = 53/392 (13%) Query: 2023 NIAEKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQ 2082 N A + G K +G GP+G GP+G+PG G G G +G PGE G PG +G Sbjct: 158 NFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPM 217 Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142 G +G PG G G G G+ G GE G G G +GLPG++G G G RG G Sbjct: 218 GPRGPPGPPGKNGDDGEAGKPGRPGE---RGPPGPQGARGLPGTAGLPGMKGHRGFSGLD 274 Query: 2143 GEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGET---GKNGG 2199 G KG+ G G +G+PG+PG++ G G +GP G+PG G PG PG G +G Sbjct: 275 GAKGDAGPAGPKGEPGSPGEN-------GAPGQMGPRGLPGERGRPGAPGPAGARGNDGA 327 Query: 2200 FGRRGPPGAKGNKGGPGQP---------------GFEGEQGTRGAQGP------AGPAGP 2238 G GPPG G G PG P G EG QG RG GP AGPAG Sbjct: 328 TGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGN 387 Query: 2239 PGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGR 2298 PG G+ G G G+ G AGAPG G GP G +G G PGPKG G G G GD G Sbjct: 388 PGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGA 447 Query: 2299 DG-------------VGSEGRRGKKGE---RGFPGYPGPKGNPGE---PGLNGTTGPKGI 2339 G G EG+RG +GE G PG PG +G PG PG +G GPKG Sbjct: 448 KGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGP 507 Query: 2340 RGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 G RG+ GP G G G+ G PG AG G +G Sbjct: 508 AGERGSPGPAGPKGSPGEAGRPGEAGLPGAKG 539 Score = 271 bits (692), Expect = 1e-71 Identities = 164/385 (42%), Positives = 187/385 (48%), Gaps = 54/385 (14%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPG------------DEGGPGERGP---PGVNGTQ 2082 G RG+ GP G GP G G G RG+PG + G PG GP PG G Sbjct: 470 GARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRP 529 Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142 G G PG +G+ GS G PG G+ G G G DG G G PG+ G+ G G G KG Sbjct: 530 GEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAA 589 Query: 2143 GEKGERGDVGIRGDPGNPGQDSQE-----------RGPKGETGDLGPMGVPGRDGVP--- 2188 GE G+ G+ G+ G PG G ++ GP GE G+ GP G PG G+P Sbjct: 590 GEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPA 649 Query: 2189 GGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGIS 2248 G PGE GK G G G GA G G G+ GF GE RG QGP GPAGP G G G Sbjct: 650 GPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGE---RGVQGPPGPAGPRGANGAPGND 706 Query: 2249 GPRGSGGAAGAPGERGRTGPLGRKGEPGE---PGPKGGIGNRGPRGETGDDGRDGV---- 2301 G +G GA GAPG +G G G GE G PGPKG G+ GP+G G G+DGV Sbjct: 707 GAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLT 766 Query: 2302 ---------------GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNS 2346 G G G G G G PG +G PG PG G GP G G+ G Sbjct: 767 GPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAK 826 Query: 2347 GPPGIVGQKGDPGYPGPAGPKGNRG 2371 G PG G KGD G PGPAGP G G Sbjct: 827 GEPGDAGAKGDAGPPGPAGPAGPPG 851 Score = 270 bits (691), Expect = 1e-71 Identities = 169/420 (40%), Positives = 205/420 (48%), Gaps = 60/420 (14%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGY---------RGYPGDEGGPGERGP---PGVNGTQGFQ 2085 G+ G +GP GS GP+G+ GE G G PG +G PG +G PG+ G GF Sbjct: 353 GEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFP 412 Query: 2086 GCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEK 2145 G G G +G G PG KG GE G G G+ G KG PG G +G PG G++G RG + Sbjct: 413 GARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGAR 472 Query: 2146 GERGDVGIRGDPGN---------PGQD--SQERGPKGETGDLGP---------------M 2179 GE G G+ G PG PG D + +GP GE G GP Sbjct: 473 GEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEA 532 Query: 2180 GVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPP 2239 G+PG G+ G PG G +G G GP G G G PG PG G+ G G GP G AG P Sbjct: 533 GLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEP 592 Query: 2240 GLIGEQGISGPRGSGGAAGAPGE---RGRTGPLGRKGEPGEPGPKGGIGNR------GPR 2290 G GE+G+ GP G+ G AG GE +G GP G GE GE GP G G + GP Sbjct: 593 GKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPP 652 Query: 2291 GETGDDGRDGV----GSEGRRGKKGERGFPGY---------PGPKGNPGEPGLNGTTGPK 2337 GE G G GV G+ G G +GERGFPG GP+G G PG +G G Sbjct: 653 GEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDA 712 Query: 2338 GIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCPCCYGPLECP 2397 G G G+ G PG+ G G+ G G GPKG+RGD+ + A KD GP+ P Sbjct: 713 GAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPP 772 Score = 268 bits (686), Expect = 5e-71 Identities = 164/433 (37%), Positives = 195/433 (45%), Gaps = 106/433 (24%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G+ G GP+G GP G PG++G G G G PGERGPPG G +G G G G+KG R Sbjct: 209 GEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHR 268 Query: 2098 GF---------------------PGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGR- 2135 GF PGE G G++G GL GE G G PG +G +GN G Sbjct: 269 GFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGAT 328 Query: 2136 -----------------------RGDKGPRGEKGERGDVGIRGDPGNPGQ-----DSQER 2167 +G+ GP+G +G G G+RG+PG PG + Sbjct: 329 GAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNP 388 Query: 2168 GPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTR 2227 G G+ G G G PG G PG PG G +G G GPPG KGN G PG PG +G+ G + Sbjct: 389 GADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAK 448 Query: 2228 GAQGP------------------------------------------------AGPAGPP 2239 G GP AGP GP Sbjct: 449 GEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPA 508 Query: 2240 GLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRD 2299 G G G +GP+GS G AG PGE G G G G PG PGP G GP G G DGR Sbjct: 509 GERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPD---GKTGPPGPAGQDGRP 565 Query: 2300 GVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPG 2359 G G G +G+ G G+PGPKG GEP G G +G+ G G GP G G+ G G Sbjct: 566 --GPPGPPGARGQAGVMGFPGPKGAAGEP---GKAGERGVPGPPGAVGPAGKDGEAGAQG 620 Query: 2360 YPGPAGPKGNRGD 2372 PGPAGP G RG+ Sbjct: 621 PPGPAGPAGERGE 633 Score = 265 bits (676), Expect = 7e-70 Identities = 163/370 (44%), Positives = 188/370 (50%), Gaps = 35/370 (9%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS- 2096 G G +GP G GPKG GE G G GD G GE GP GV G G G G+RG +G Sbjct: 416 GPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEP 475 Query: 2097 --RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154 G PG GE G G G G DG G G +GE+G+PG G KG GE G G+ G+ Sbjct: 476 GPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLP 535 Query: 2155 GDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP------PGA 2208 G G G GP G+TG GP G GR G PG PG G+ G G GP PG Sbjct: 536 GAKGLTGSPGSP-GPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGK 594 Query: 2209 KGNKGGPGQPGF---EGEQGTRGAQGPAGPAGPPGLIGEQGISGP---RGSGGAAGAPGE 2262 G +G PG PG G+ G GAQGP GPAGP G GEQG +G +G G AG PGE Sbjct: 595 AGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGE 654 Query: 2263 RGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-------GSEGRRGKKGERGF 2315 G+ G G G+ G PGP G G RG GE G G G G+ G G KG+ G Sbjct: 655 AGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGA 714 Query: 2316 PGYPGPKGNPG---EPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGY---------PGP 2363 PG PG +G PG PG G G G +G RG++GP G G G G PGP Sbjct: 715 PGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGP 774 Query: 2364 AGPKGNRGDS 2373 AG G++G+S Sbjct: 775 AGAPGDKGES 784 Score = 264 bits (675), Expect = 9e-70 Identities = 158/378 (41%), Positives = 185/378 (48%), Gaps = 44/378 (11%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGV---NGTQGFQGCPGQRGV 2093 +G +G G G G G+PG G G PG G G+ GPPG +G G G PG RG Sbjct: 517 AGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQ 576 Query: 2094 KGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI 2153 G GFPG KG GE G G G G G G +G+ G G +G GP G GERG+ G Sbjct: 577 AGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGP 636 Query: 2154 RGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRR---GPP---- 2206 G PG G GP GE G G GVPG G PG G G+ G G R GPP Sbjct: 637 AGSPGFQGLPG-PAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAG 695 Query: 2207 -----------GAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGG 2255 GAKG+ G PG PG +G G +G G G AG PG G++G +GP+G+ G Sbjct: 696 PRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADG 755 Query: 2256 AAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG--------------- 2300 + G G RG TGP+G G G PG KG G GP G TG G G Sbjct: 756 SPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAG 815 Query: 2301 -VGSEGRRGKKGE------RGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVG 2353 G++G+ G KGE +G G PGP G G PG G G G +G RG++GPPG G Sbjct: 816 PPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATG 875 Query: 2354 QKGDPGYPGPAGPKGNRG 2371 G G GP GP GN G Sbjct: 876 FPGAAGRVGPPGPSGNAG 893 Score = 260 bits (664), Expect = 2e-68 Identities = 157/371 (42%), Positives = 175/371 (47%), Gaps = 49/371 (13%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGV------------------- 2078 G +GD GP G GP G PG DG G PG G PG GPPG Sbjct: 112 GPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKS 171 Query: 2079 ------------NGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGS 2126 +G +G G PG G +G +G PGE GE G G G G G G G Sbjct: 172 TGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGD 231 Query: 2127 SGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDG 2186 GE G PGR G++GP G +G RG G G PG G RG G G G G G G Sbjct: 232 DGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGH----RGFSGLDGAKGDAGPAGPKG 287 Query: 2187 VPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQG 2246 PG PGE G G G RG PG +G G PG G G G GA GP GP GP G G Sbjct: 288 EPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAG---PPG 344 Query: 2247 ISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGR 2306 G G+ G AG G RG GP G +GEPG PGP G GP G G DG+ G++G Sbjct: 345 FPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGA---AGPAGNPGADGQP--GAKGA 399 Query: 2307 RGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDP------GY 2360 G G G PG+PG +G G G G GPKG G G G G G KG+P G Sbjct: 400 NGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGP 459 Query: 2361 PGPAGPKGNRG 2371 PGPAG +G RG Sbjct: 460 PGPAGEEGKRG 470 Score = 257 bits (656), Expect = 1e-67 Identities = 143/329 (43%), Positives = 167/329 (50%), Gaps = 24/329 (7%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G G+ GP G GP G G G RG G G PGE GPPG G G +G PG G G+ Sbjct: 887 GPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAP 946 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157 G PG +G G+ G+ GL G+ G++G PG G G PG++G G GE+G G +G G Sbjct: 947 GTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLA 1006 Query: 2158 GNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQ 2217 G PG+ +E P E G PGRDG PG G+ G+ G G G PGA G G G Sbjct: 1007 GPPGESGREGAPGAE-------GSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGP 1059 Query: 2218 PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGE 2277 G G++G G GPAGP GP G G G GPRG G G G+RG G G G G Sbjct: 1060 AGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGP 1119 Query: 2278 PGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPK 2337 PGP G G +GP G +G G G PG G PG+ GLNG GP Sbjct: 1120 PGPPGSPGEQGPSGASGPAGPRGP-----------------PGSAGAPGKDGLNGLPGPI 1162 Query: 2338 GIRGRRGNSGPPGIVGQKGDPGYPGPAGP 2366 G G RG +G G VG G PG PGP GP Sbjct: 1163 GPPGPRGRTGDAGPVGPPGPPGPPGPPGP 1191 Score = 221 bits (562), Expect = 1e-56 Identities = 140/321 (43%), Positives = 161/321 (50%), Gaps = 58/321 (18%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPG---DEGGPGERGPPGVNGTQGFQGCPGQRGV 2093 +G+ G +GP G GP G PGE G G PG ++G PG GP G GT G QG GQRGV Sbjct: 901 AGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGV 960 Query: 2094 KGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI 2153 G PG++GE G GL G GE G +G G+SGE+G PG G G G GE G G Sbjct: 961 VG---LPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGA 1017 Query: 2154 RGDPGNPGQDSQE--RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA--- 2208 G G+PG+D +G +GETG GP G PG G PG G GK+G G GP G Sbjct: 1018 PGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGP 1077 Query: 2209 ---------------KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISG---- 2249 +G+KG G+ G G +G RG G GP GPPG GEQG SG Sbjct: 1078 VGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGP 1137 Query: 2250 --PRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRR 2307 PRG G+AGAPG+ G G PGP IG GPRG TGD Sbjct: 1138 AGPRGPPGSAGAPGKDGLN---------GLPGP---IGPPGPRGRTGD------------ 1173 Query: 2308 GKKGERGFPGYPGPKGNPGEP 2328 G G PG PGP G PG P Sbjct: 1174 --AGPVGPPGPPGPPGPPGPP 1192 Score = 196 bits (498), Expect = 3e-49 Identities = 131/331 (39%), Positives = 152/331 (45%), Gaps = 34/331 (10%) Query: 2058 DGYRGYPGDEGGPGERGPPGVNGTQG--FQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLD 2115 D + PG E GE P +G++ Q G G KG G G +G G G DG+ Sbjct: 76 DETKNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIP 135 Query: 2116 GEDGDKGLPGSSGEKGNPGRRGDKGPRGEKG--ERGDVGIRGDPGNPGQDSQERGPKGET 2173 G+ G G PG G G PG G+ P+ G E+ GI PG G GP+G Sbjct: 136 GQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGI-SVPGPMGPS----GPRGLP 190 Query: 2174 GDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPA 2233 G G G G G PG PGE G +G G RGPPG G G G+ G G G RG GP Sbjct: 191 GPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQ 250 Query: 2234 GPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPK---------GGI 2284 G G PG G G+ G RG G GA KG+ G GPK G Sbjct: 251 GARGLPGTAGLPGMKGHRGFSGLDGA------------KGDAGPAGPKGEPGSPGENGAP 298 Query: 2285 GNRGPRGETGDDGRDG----VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIR 2340 G GPRG G+ GR G G+ G G G G PG GP G PG PG G G G + Sbjct: 299 GQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQ 358 Query: 2341 GRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 G RG+ GP G+ G+ G PG G AGP GN G Sbjct: 359 GPRGSEGPQGVRGEPGPPGPAGAAGPAGNPG 389 Score = 160 bits (405), Expect = 2e-38 Identities = 96/225 (42%), Positives = 109/225 (48%), Gaps = 19/225 (8%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRG 2092 P SG+RG GP+G G G PGE G G PG EG PG G PG G +G G G G Sbjct: 987 PSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPG 1046 Query: 2093 VKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVG 2152 G+ G PG G G+ G G G G G G G +G G +G +G +GE GE+GD Sbjct: 1047 APGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGD-- 1104 Query: 2153 IRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPP---GAK 2209 RG KG G G G PG G PG G +G +G G RGPP GA Sbjct: 1105 --------------RGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAP 1150 Query: 2210 GNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSG 2254 G G G PG G G RG G AGP GPPG G G GP +G Sbjct: 1151 GKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAG 1195 Score = 151 bits (381), Expect = 1e-35 Identities = 92/227 (40%), Positives = 106/227 (46%), Gaps = 27/227 (11%) Query: 2169 PKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRG 2228 P+GE + P G P TG G G GP G +G G PG+ G G+ G G Sbjct: 87 PEGECCPVCPDGSES----PTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPG 142 Query: 2229 AQGPAGPAGPPGLIGE----------------------QGISGPRGSGGAAGAPGERGRT 2266 GP GP GPPGL G G SGPRG G GAPG +G Sbjct: 143 PPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQ 202 Query: 2267 GPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNP 2325 GP G GEPG GP G G GP G+ GDDG G G G RG G +G G PG G P Sbjct: 203 GPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLP 262 Query: 2326 GEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 G G G +G G +G G +GP G G G+ G PG GP+G G+ Sbjct: 263 GMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGE 309 Score = 79.0 bits (193), Expect = 7e-14 Identities = 49/131 (37%), Positives = 54/131 (41%), Gaps = 39/131 (29%) Query: 2276 GEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGT-- 2333 G GPKG G RGPRG G GRDG+ G+ G PG PGP G PG PGL G Sbjct: 109 GVEGPKGDTGPRGPRGPAGPPGRDGI--------PGQPGLPGPPGPPGPPGPPGLGGNFA 160 Query: 2334 -----------------------------TGPKGIRGRRGNSGPPGIVGQKGDPGYPGPA 2364 GP G G +G GPPG G+ G G GP Sbjct: 161 PQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPR 220 Query: 2365 GPKGNRGDSID 2375 GP G G + D Sbjct: 221 GPPGPPGKNGD 231 Score = 47.0 bits (110), Expect = 3e-04 Identities = 26/60 (43%), Positives = 29/60 (48%), Gaps = 6/60 (10%) Query: 2317 GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQ 2376 G GPKG+ G GP+G G G G PG G G PG PGP GP G G+ Q Sbjct: 109 GVEGPKGD------TGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQ 162 >gi|154759255 collagen, type XXVIII precursor [Homo sapiens] Length = 1125 Score = 301 bits (772), Expect = 5e-81 Identities = 203/531 (38%), Positives = 275/531 (51%), Gaps = 65/531 (12%) Query: 2038 GQRGDRGPIGSIGPKGIPG--EDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKG 2095 G++GD GP+G GP GIPG G +G G G PG +GP G G G +G GQ G G Sbjct: 432 GEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTG 490 Query: 2096 SRG-----FPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGP--RGEKGER 2148 RG G KGE G IGL G G G+ G G GE G PG RG +GP +G+ G + Sbjct: 491 PRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPK 550 Query: 2149 GDVGIRGDPGNPGQDSQE--RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPP 2206 GD G +G GN GQ GPKGE G +GP G+PG +PG PP Sbjct: 551 GDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTS-IPG---------------PP 594 Query: 2207 GAKGNKGGPGQPGFEGE-----QGTRGAQGPAGPAGPPGLIGE--QGISGPRGSGGAAGA 2259 G KG++GGPG PGF+GE +G +G QGP GP G PGL G+ G+ GPRG G G Sbjct: 595 GPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGP 654 Query: 2260 PGERGRTGPLGRKGEPGEPGPKG-----GIGNRGPRGETGDDGRDGVGSE---GRRGKKG 2311 G RG G G KGEPG GP G G+G +GP+G+TG G G G +G KG Sbjct: 655 MGLRG-VGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKG 713 Query: 2312 ERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 E+G G+PGPKG G +G G KG G RG+ G G G+ G+PG PG G +G +G Sbjct: 714 EQGPQGFPGPKGTMG----HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKG 769 Query: 2372 D-SIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVN 2430 D + + +I+ I + C C GP +C P EL F +D+SE V + F +++ V ++ + Sbjct: 770 DLGLTKEEIIKLITEICGC--GP-KCKETPLELVFVIDSSESVGPENFQIIKNFVKTMAD 826 Query: 2431 DLTIAESNCPRGARVAVVTYNNEVTTEIRFADSKRKSVLLDKIKNLQVALTSKQQSLETA 2490 + + + AR+ ++ Y+++V K + N+Q + TA Sbjct: 827 RVALDLAT----ARIGIINYSHKVEKVANLKQFSSKDDFKLAVDNMQYL----GEGTYTA 878 Query: 2491 MSFVARN-TFKRVRNGFLMRKVAVFFSN--TPTRASPQLREAVLKLSDAGI 2538 + A N F+ R G ++KVA+ ++ T +R +L E V SD + Sbjct: 879 TALQAANDMFEDARPG--VKKVALVITDGQTDSRDKEKLTEVVKNASDTNV 927 Score = 269 bits (688), Expect = 3e-71 Identities = 214/601 (35%), Positives = 286/601 (47%), Gaps = 82/601 (13%) Query: 1835 CNLDVILGFDGSRDQNV--FVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVAN 1892 C +D++ D S + F QK F VD++ ++I Q+ + GRS + + A Sbjct: 45 CFIDIVFIVDSSESSKIALFDKQKDF---VDSLSDKIFQL-----TPGRSLEYDIKLAAL 96 Query: 1893 TPSGPVEAF-------DFDEYQPEMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSV 1945 S V+ D ++ ++ K N+ Q + + L K R+ D V Sbjct: 97 QFSSSVQIDPPFSSWKDLQTFKQKV--KSMNLIGQGTFSYYAISNATRLLK-REGRKDGV 153 Query: 1946 KVVIHFTDGADGDL-ADLHRASENLRQEGVRALILVGLERVVNLERLMHLEFGRGFMYDR 2004 KVV+ TDG D D+ SE+ R G+ + I + L VVN +L + G Sbjct: 154 KVVLLMTDGIDHPKNPDVQSISEDARISGI-SFITIALSTVVNEAKLRLIS---GDSSSE 209 Query: 2005 P-LRLNLLDLDYELAEQLDNIAEKACCGVPCKCS-GQRGDRGPIGSIGPKGIPGEDGYRG 2062 P L L+ L ++ ++LD + EK C C+C G GD GP G+ G GI GE G +G Sbjct: 210 PTLLLSDPTLVDKIQDRLDILFEKKCERKICECEKGDPGDPGPPGTHGNPGIKGERGPKG 269 Query: 2063 YPGD--EGGPGERGP---PGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGE 2117 PG+ +G GERGP PG G +G +G G+ G+KG +G PG G G G+ G+ G Sbjct: 270 NPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGP 329 Query: 2118 DGDKGLPGSSGEKGNPGRRGDKGPRG-----EKGERGDVGIRGDPGNPGQDSQERGPKGE 2172 GD G G G KG PG G G G ++G +G+ G G PG PG G G+ Sbjct: 330 PGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIGV--GEPGQ 387 Query: 2173 TGDLGPMGVPGRDGVPGG--PGETGKNGGFGRRGPPGA-----KGNKG-----GPGQP-- 2218 G GP GVPG G+PG PG G+ G G GP G KG KG GP P Sbjct: 388 PGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMG 447 Query: 2219 ----GFEGEQGTRGAQGPAGPAGPPGL--------IGEQGISGPRGSGGAAGAPGERGRT 2266 G +GEQG +G GP GP GP G +G+ G +GPRG G G G +G Sbjct: 448 IPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEP 506 Query: 2267 GPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV------------GSEGRRGKKGERG 2314 G +G G+PG PG G G +G G G G +G G +G +G +G+RG Sbjct: 507 GSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRG 566 Query: 2315 FPGYPGPKGNPGEPGLNGTTGPK--GIRGRRGNSGPPGIVGQKGDPGYP--GPAGPKGNR 2370 PG GPKG PG G G G G G +G+ G PGI G KG+PG GP G +G R Sbjct: 567 LPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPR 626 Query: 2371 G 2371 G Sbjct: 627 G 627 Score = 153 bits (386), Expect = 3e-36 Identities = 89/203 (43%), Positives = 106/203 (52%), Gaps = 15/203 (7%) Query: 2172 ETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQG 2231 E GD G G PG G PG GE G G G G G +G G PG++G++G RG G Sbjct: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPGYKGDKGERGECG 301 Query: 2232 PAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRG 2291 G G G G G GPRG G G PG+ G G G KGEPG PGP G Sbjct: 302 KPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGS-------- 353 Query: 2292 ETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGI 2351 G G+G +G +G++G+ G PG PGP G GEPG G GP+G+ G RG G G Sbjct: 354 ----PGAPGIGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPG-EGF 407 Query: 2352 VGQKGDPGYPGPAGPKGNRGDSI 2374 G KG+ G GP GP+G +G SI Sbjct: 408 PGPKGEKGSEGPTGPQGLQGLSI 430 Score = 96.7 bits (239), Expect = 3e-19 Identities = 64/144 (44%), Positives = 80/144 (55%), Gaps = 15/144 (10%) Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQ 2090 GVP G RG GP G +G +G+ G+ G +G PG G PG GP GV GTQG +G GQ Sbjct: 641 GVP----GPRGLPGPPGPMGLRGV-GDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTGQ 694 Query: 2091 RGVKGSRGFPGE-----KGEVGEIGLDGLDGEDGDKGLPGSSGE---KGNPGRRGDKGPR 2142 +G+ G G PG KGE G G G G G GLPG GE +G+ G++GDKG Sbjct: 695 KGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMGH-GLPGQKGEHGERGDVGKKGDKGEI 753 Query: 2143 GEKGERGDVGIRGDPGNPGQDSQE 2166 GE G G G++G G+ G +E Sbjct: 754 GEPGSPGKQGLQGPKGDLGLTKEE 777 Score = 72.8 bits (177), Expect = 5e-12 Identities = 30/79 (37%), Positives = 47/79 (59%), Gaps = 1/79 (1%) Query: 3084 PQPARSASSSTINLMVSTEPLALTETDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYG 3143 P S +++T ++ST P+ E C G C +++++WYYD SCARFW+ Sbjct: 1045 PATTSSEATTTPRPLLST-PVDGAEDPRCLEALKPGNCGEYVVRWYYDKQVNSCARFWFS 1103 Query: 3144 GCGGNENKFGSQKECEKVC 3162 GC G+ N+F S+KEC++ C Sbjct: 1104 GCNGSGNRFNSEKECQETC 1122 Score = 60.1 bits (144), Expect = 3e-08 Identities = 53/203 (26%), Positives = 90/203 (44%), Gaps = 24/203 (11%) Query: 1411 LTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGP 1470 LT E+I KL+ P + ++VF+IDSSE V P+ F I++FV + R+ + Sbjct: 773 LTKEEIIKLITEICGCGPKCKETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVALDL 832 Query: 1471 SKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVK 1530 + R+G++ +S+ V LK + S+ A+ ++ G T AL+ Sbjct: 833 ATARIGIINYSHKVEKVANLKQFSSKDDFKLAVDNMQYLGEGTY-TATALQ--------- 882 Query: 1531 SAGSRIEDGVP----QHLVLVLGGKSQDDVSRFAQVIRSSG-----IVSLGVGDRN---- 1577 +A ED P LV+ G D + +V++++ I +GV +N Sbjct: 883 AANDMFEDARPGVKKVALVITDGQTDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNF 942 Query: 1578 -IDRTELQTITNDPRLVFTVREF 1599 I E+ I DP V+ +F Sbjct: 943 EIFHKEMNLIATDPEHVYQFDDF 965 Score = 58.5 bits (140), Expect = 1e-07 Identities = 48/198 (24%), Positives = 89/198 (44%), Gaps = 19/198 (9%) Query: 631 PEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTE 690 P+ +++F++D S +VG NF +++FV + + + + R+G++ +S Sbjct: 790 PKCKETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGIINYSHKVEKV 849 Query: 691 FSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLL 750 +L + +K D + +Q G G T +AL AN E R V ++ L++ Sbjct: 850 ANLKQFSSKDDFKLAVDNMQYL-GEGTYTATALQ--AANDMFEDA----RPGVKKVALVI 902 Query: 751 TAGQSE----DSYLQAANALTRAGILTFCVGASQAN-------KAELEQIAFNPSLVYLM 799 T GQ++ + + + + F +G + N E+ IA +P VY Sbjct: 903 TDGQTDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIATDPEHVYQF 962 Query: 800 DDFSSL-PALPQQLIQPL 816 DDF +L L Q+L Q + Sbjct: 963 DDFFTLQDTLKQKLFQKI 980 Score = 58.2 bits (139), Expect = 1e-07 Identities = 43/180 (23%), Positives = 84/180 (46%), Gaps = 17/180 (9%) Query: 39 DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRT 98 +++F++DSS ++G E+FQ+++ F+ + +A+ ++ ++ L + + Sbjct: 798 ELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGIINYSHKVEKVANLKQFSS 857 Query: 99 KQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGH--SKD 156 K + + NM Y+G T L+ A GV +V +V+TDG S+D Sbjct: 858 KDDFKLAVDNMQYLGEGTYTATALQ------AANDMFEDARPGVKKVALVITDGQTDSRD 911 Query: 157 GLALPSAELKSADVNV--FAIGVEDADEGALKEIASEPLNM------HMFNLENFTSLHD 208 L ++D NV F IGV ++ EI + +N+ H++ ++F +L D Sbjct: 912 KEKLTEVVKNASDTNVEIFVIGVVKKNDPNF-EIFHKEMNLIATDPEHVYQFDDFFTLQD 970 Score = 52.8 bits (125), Expect = 5e-06 Identities = 58/236 (24%), Positives = 104/236 (44%), Gaps = 25/236 (10%) Query: 1208 LTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGF 1266 LT+EE+ +L + ++VF+ID S+S GPE FQ ++ ++ + D + + Sbjct: 773 LTKEEIIKLITEICGCGPKCKETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVALDL 832 Query: 1267 DTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFK- 1325 T R+ +I +S + L SSKD+ + AV ++ G AL+ + ++F+ Sbjct: 833 ATARIGIINYSHKVEKVANLKQFSSKDDFKLAVDNMQYL-GEGTYTATALQ-AANDMFED 890 Query: 1326 -RPLGSRIEEGVPQFLVLISSGKSDD-----------EVDDPAVELKQFGVAPFTIAR-N 1372 RP GV + ++I+ G++D D VE+ GV Sbjct: 891 ARP-------GVKKVALVITDGQTDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFE 943 Query: 1373 ADQEELVKISLSPEYVFSVSTFREL-PSLEQKLLTPITTLTSEQIQKLLASTRYPP 1427 +E+ I+ PE+V+ F L +L+QKL I + ++ S+ P Sbjct: 944 IFHKEMNLIATDPEHVYQFDDFFTLQDTLKQKLFQKICEDFDSYLVQIFGSSSPQP 999 Score = 48.5 bits (114), Expect = 1e-04 Identities = 33/143 (23%), Positives = 69/143 (48%), Gaps = 11/143 (7%) Query: 445 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 504 ++VF++D S ++G NF I++F+ + R+ + ++ + Y+ V + Sbjct: 798 ELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGIINYSHKVEKVANLKQFSS 857 Query: 505 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGG----K 560 K + AV M+ L G YT +AL N++F A G+ K+ ++IT G + Sbjct: 858 KDDFKLAVDNMQYL-GEGTYTATALQ-AANDMFED-----ARPGVKKVALVITDGQTDSR 910 Query: 561 SLDEISQPAQELKRSSIMAFAIG 583 +++++ + +++ F IG Sbjct: 911 DKEKLTEVVKNASDTNVEIFVIG 933 Score = 46.6 bits (109), Expect = 4e-04 Identities = 46/190 (24%), Positives = 88/190 (46%), Gaps = 19/190 (10%) Query: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 301 +++F+ID S + G NF +I +F+ + +++ + R+G++ +S + + +L +S+ Sbjct: 798 ELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGIINYSHKVEKVANLKQFSS 857 Query: 302 KAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDE 361 K AV + + GE AL + F A GV +V ++I+ G + Sbjct: 858 KDDFKLAVDNMQYL-GEGTYTATALQ-AANDMFEDA-----RPGVKKVALVITDGQTDSR 910 Query: 362 IRYGVV-ALKQAS-----VFSFGLGAQAASRAELQH-----IATDDNLVFTVPEFRSFGD 410 + + +K AS +F G+ + E+ H IATD V+ +F + D Sbjct: 911 DKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIATDPEHVYQFDDFFTLQD 970 Query: 411 -LQEKLLPYI 419 L++KL I Sbjct: 971 TLKQKLFQKI 980 Score = 44.7 bits (104), Expect = 0.001 Identities = 54/243 (22%), Positives = 102/243 (41%), Gaps = 20/243 (8%) Query: 1002 IGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVR-SGFPLLKEFVQRVVESLDV 1060 +G +I+ L+ + P ++VF++D SE V F ++K FV+ + + + + Sbjct: 771 LGLTKEEIIKLITEICGCGPKCKETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVAL 830 Query: 1061 GQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNIL 1120 R+ ++ YS + L + +K D AV + LG T T AL+ N + Sbjct: 831 DLATARIGIINYSHKVEKVANLKQFSSKDDFKLAVDNMQYLGEGT-YTATALQ--AANDM 887 Query: 1121 VSSAGSRITEGVPQLLIVLTADRSGD-DVRNPSVVVKRGGAVPIGIGI--------GNAD 1171 A GV ++ +V+T ++ D + VVK + I + N + Sbjct: 888 FEDA----RPGVKKVALVITDGQTDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFE 943 Query: 1172 I--TEMQTISFIPDFAVAIPTFRQL-GTVQQVISERVTQLTREELSRLQPVLQPLPSPGV 1228 I EM I+ P+ F L T++Q + +++ + L ++ P P G+ Sbjct: 944 IFHKEMNLIATDPEHVYQFDDFFTLQDTLKQKLFQKICEDFDSYLVQIFGSSSPQPGFGM 1003 Query: 1229 GGK 1231 G+ Sbjct: 1004 SGE 1006 Score = 43.5 bits (101), Expect = 0.003 Identities = 36/169 (21%), Positives = 73/169 (43%), Gaps = 17/169 (10%) Query: 2613 GSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPS 2672 GS ID+ FI+DS+E++ + F++ K ++ L ++ ++ ++ ++A +Q + S Sbjct: 42 GSICFIDIVFIVDSSESSKIALFDKQKDFVDSLSDKIFQLTPGRSLEYDIKLAALQFSSS 101 Query: 2673 ESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFE--SA 2730 +D PP L + K K ++ + +G Y I N Sbjct: 102 VQID----PPFSSWKDLQTFKQKVKSMNLIGQGTFSY-----------YAISNATRLLKR 146 Query: 2731 PNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVN 2779 +D VVL++T + + + Q + A+ G F+ + + VN Sbjct: 147 EGRKDGVKVVLLMTDGIDHPKNPDVQSISEDARISGISFITIALSTVVN 195 Score = 43.5 bits (101), Expect = 0.003 Identities = 36/144 (25%), Positives = 64/144 (44%), Gaps = 11/144 (7%) Query: 1639 DIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFST 1698 ++VF++D S + ++FQ + FV + D V D + ++G++ Y+ LK FS+ Sbjct: 798 ELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGIINYSHKVEKVANLKQFSS 857 Query: 1699 KRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGG----K 1754 K A++ + Y G T N +A V ++A VIT G + Sbjct: 858 KDDFKLAVDNMQYLG---EGTYTATALQAANDMFEDA----RPGVKKVALVITDGQTDSR 910 Query: 1755 SVEDAQDVSLALTQRGVKVFAVGV 1778 E +V + V++F +GV Sbjct: 911 DKEKLTEVVKNASDTNVEIFVIGV 934 Score = 33.9 bits (76), Expect = 2.6 Identities = 49/223 (21%), Positives = 90/223 (40%), Gaps = 28/223 (12%) Query: 1436 DIVFLIDSSEGVRPDGFAHIRDFVSRI---VRRLNIGPS---KVRVGVVQFSNDVFPEFY 1489 DIVF++DSSE + F +DFV + + +L G S +++ +QFS+ V + Sbjct: 48 DIVFIVDSSESSKIALFDKQKDFVDSLSDKIFQLTPGRSLEYDIKLAALQFSSSVQIDPP 107 Query: 1490 LKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLG 1549 +++ ++ + L G + A+ R +K G + DGV L++ G Sbjct: 108 FSSWKDLQTFKQKVKSMNLIGQGTFSY-YAISNATR--LLKREGRK--DGVKVVLLMTDG 162 Query: 1550 --GKSQDDVSRFAQVIRSSGIVSLGVGDRNI------------DRTELQTITNDPRLVFT 1595 DV ++ R SGI + + + +E + +DP LV Sbjct: 163 IDHPKNPDVQSISEDARISGISFITIALSTVVNEAKLRLISGDSSSEPTLLLSDPTLVDK 222 Query: 1596 VREFREL---PNIEERIMNSFGPSAATPAPPGVDTPPPSRPEK 1635 +++ ++ E +I P PPG P + E+ Sbjct: 223 IQDRLDILFEKKCERKICECEKGDPGDPGPPGTHGNPGIKGER 265 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 298 bits (762), Expect = 7e-80 Identities = 176/397 (44%), Positives = 202/397 (50%), Gaps = 63/397 (15%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G G++GP+G G G+PG DG G+PG EG PGE+G G G QG G PG RGVKG+ Sbjct: 739 GPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGAD 798 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEK------------ 2145 G G KG GE G DG G GD G+ G GE G PG RG+ GP G K Sbjct: 799 GIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPL 858 Query: 2146 ---GERGDVGI------------------------------RGDPGNPGQDSQ------- 2165 GE+G +G+ RG PG PG Q Sbjct: 859 GPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPR 918 Query: 2166 -ERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQ---PGFE 2221 ERGP+G TG GP G G DG G PGE G NG G G PG KG G PG+ PG Sbjct: 919 GERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHP 978 Query: 2222 GEQGTRGAQGPAGPAGPPGLIGEQGIS------GPRGSGGAAGAPGERGRTGPLGRKGEP 2275 G++G G QG GP GPPG++G QG + G RG G G PGE+G G G++G Sbjct: 979 GQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTK 1038 Query: 2276 GEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTT 2334 G+PGP G G GP G G G G+ G G G KG G PG PGP G+PGE G G Sbjct: 1039 GDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAA 1098 Query: 2335 GPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 GP GI GR G GPPG G+KG PG GP GP G G Sbjct: 1099 GPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1135 Score = 288 bits (737), Expect = 6e-77 Identities = 166/376 (44%), Positives = 195/376 (51%), Gaps = 47/376 (12%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPG------DEGGPGERGPPGVNGTQGFQGCPGQR 2091 G G +GPIG GP G GE G RG G DEG G GPPG G QG G PG++ Sbjct: 1180 GPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEK 1239 Query: 2092 GVKGSRGF------PGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKG----- 2140 G G G PG +G G G DG G G G PG+ GEKG PG G+ G Sbjct: 1240 GETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEG 1299 Query: 2141 ----PRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGK 2196 P+GE+GE+G+ G G G PG PKG GD GP G PG G PG PG G+ Sbjct: 1300 GPPGPKGERGEKGESGPSGAAGPPG-------PKGPPGDDGPKGSPGPVGFPGDPGPPGE 1352 Query: 2197 NGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGA 2256 G G+ GPPG KG+ G PGQ G G G G GP G GPPG G +G G +G+ G Sbjct: 1353 PGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGE 1412 Query: 2257 AGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-------------VGS 2303 AG G G+TGP+G +G PG+PGP G G GP GE G G G G Sbjct: 1413 AGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGL 1472 Query: 2304 EGRRGKKGERGFPGY------PGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGD 2357 +G G KGE+G PG PG +G G+ GL G G G +G +G +GP G +G G Sbjct: 1473 KGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGP 1532 Query: 2358 PGYPGPAGPKGNRGDS 2373 PG PGP GPKG +G S Sbjct: 1533 PGLPGPPGPKGAKGSS 1548 Score = 287 bits (735), Expect = 1e-76 Identities = 179/434 (41%), Positives = 212/434 (48%), Gaps = 99/434 (22%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPG---DEGGPGERGPPGVNGTQGFQGCPGQRGV 2093 +G G+RGP G+ GP GIPG G +G PG ++G PGE+GP G G G QG G G Sbjct: 1086 AGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGP 1145 Query: 2094 KGSRGFPGEKGEVGEIGLDGLDGEDGDK---------------GLPGSSGEKGNP----- 2133 G G PGE G+ GEIG G G GDK G PG SG G P Sbjct: 1146 AGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQ 1205 Query: 2134 ----GRRGDKGPRGEKGERGDVGIRGDPGNPGQ-----DSQERGPKGETGDLGPMGVPGR 2184 G++GD+GPRG G G VG++G PG PG+ D + GP G G GP G PG Sbjct: 1206 QGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGA 1265 Query: 2185 DGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQ---PGFEGEQGTRGAQGPAGPAGPPGL 2241 DG G PG G G G +G PG G G PG+ PG +GE+G +G GP+G AGPPG Sbjct: 1266 DGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGP 1325 Query: 2242 IGEQGISGPRGSGGAAGAPGE---RGRTGPLGRKGEP------------------GEPGP 2280 G G GP+GS G G PG+ G GP G+ G P GEPGP Sbjct: 1326 KGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGP 1385 Query: 2281 KGGIGNRGPRGETGDDGRDG-------------------VGSEGRRGKK----------- 2310 G G RGP G G +GR G +G +G GK Sbjct: 1386 SGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGP 1445 Query: 2311 -GERGFPGYPGPKGNPGE------PGLNGTTGPKGIRGRR---GNSGPPGIVGQKGDPGY 2360 GE+G PG PGP G PG PGL G +GPKG +G G GPPG G+KGD G Sbjct: 1446 VGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGL 1505 Query: 2361 PGP---AGPKGNRG 2371 PGP +GPKG +G Sbjct: 1506 PGPQGSSGPKGEQG 1519 Score = 278 bits (710), Expect = 8e-74 Identities = 164/356 (46%), Positives = 186/356 (52%), Gaps = 29/356 (8%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G RG GP G +G +G+PG G +G GD G G GPPG G G G G +G G Sbjct: 1216 GPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGI 1275 Query: 2098 GFPG---EKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD---- 2150 G PG EKGE GE G GL GE G G G GEKG G G GP G KG GD Sbjct: 1276 GNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPK 1335 Query: 2151 -----VGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP 2205 VG GDPG PG+ G G GD G G PG+ G PG GE G +G G+RGP Sbjct: 1336 GSPGPVGFPGDPGPPGEPGPA-GQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGP 1394 Query: 2206 PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGP------PGLIGEQGISGPRGSGGAAGA 2259 PG G +G G+ G +GE G G G GP GP PG G +GI GP G G G+ Sbjct: 1395 PGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGS 1454 Query: 2260 PGERGRTGPLGRKGEPG---EPGPKGG------IGNRGPRGETGDDGRDGV-GSEGRRGK 2309 PG G GP+G G PG + GPKG IG GP GE G+ G G+ G +G G Sbjct: 1455 PGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGP 1514 Query: 2310 KGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAG 2365 KGE+G G GP G PG PGL G GPKG +G G +GP G G G PG PGP G Sbjct: 1515 KGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPG 1570 Score = 277 bits (709), Expect = 1e-73 Identities = 161/354 (45%), Positives = 193/354 (54%), Gaps = 18/354 (5%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096 +G++G RG G GP+G G G RG G G G+ GP G +G G G PG+RG G Sbjct: 894 NGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGP 953 Query: 2097 R---GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI 2153 + GFPG KG G G DGL G G +G G G+ G PG G GP+G GE G +G Sbjct: 954 QGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGE 1013 Query: 2154 RGDPGNPGQDSQE-----RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208 RG PG PG ++ G +G GD GP G+PG+DG PG G G G G G G Sbjct: 1014 RGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGL 1073 Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2268 KGN+G PG PG G G R GPAG AGP G+ G G GP G G GAPGE+G GP Sbjct: 1074 KGNEGPPGPPGPAGSPGER---GPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGP 1130 Query: 2269 LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGE 2327 GR G G G G G GP GE GD G G G +G +G KGE+G PG GP+G G+ Sbjct: 1131 AGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQ 1190 Query: 2328 PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPA------GPKGNRGDSID 2375 PG +G G G RG++G G G G +G PG PGP GP G +G++ D Sbjct: 1191 PGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGD 1244 Score = 275 bits (704), Expect = 4e-73 Identities = 158/353 (44%), Positives = 188/353 (53%), Gaps = 20/353 (5%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDG---YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094 G+ G GP G +GP+G GE G RG+PG G PGE+G PG+ G +G +G PG G+ Sbjct: 988 GKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLP 1047 Query: 2095 GS------RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGP---RGEK 2145 G RGFPG++G G +G GL G +G G PG +G G G G GP G Sbjct: 1048 GKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRP 1107 Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP 2205 G +G G G+ G PG+ + GP G G GP+G+PG G G PGE G G G G Sbjct: 1108 GPQGPPGPAGEKGAPGEKGPQ-GPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQ 1166 Query: 2206 PGAKGNKGGPGQPGFEGEQGTRGAQGPA------GPAGPPGLIGEQGISGPRGSGGAAGA 2259 G+KG+KG G PG G QG G GP+ GP G GL G++G GPRG G G Sbjct: 1167 KGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGP 1226 Query: 2260 PGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGY 2318 G +G GP G KGE G+ G G G GPRG +G G DG G G G G G G Sbjct: 1227 VGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGE 1286 Query: 2319 PGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 PG G PG PG G GPKG RG +G SGP G G G G PG GPKG+ G Sbjct: 1287 PGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPG 1339 Score = 272 bits (695), Expect = 4e-72 Identities = 156/351 (44%), Positives = 187/351 (53%), Gaps = 30/351 (8%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGP------------GERGPPGVNGTQGF 2084 +G G+RGP G GP G PG G G PG +G P G+ GPPG G G Sbjct: 942 AGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGP 1001 Query: 2085 QGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSS---GEKGNPGRRGDKGP 2141 QG G+ G G RG PG G GE GL GL G++G KG PG + G+ G PG RG G Sbjct: 1002 QGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGD 1061 Query: 2142 RGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFG 2201 RG G G +G++G+ G PG GP G G+ GP G G G+PG PG G G G Sbjct: 1062 RGLPGPVGALGLKGNEGPPGPP----GPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAG 1117 Query: 2202 RRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPG 2261 +G PG KG +G G+ +G QG G GPAGP GPPG G++G G G G+ G G Sbjct: 1118 EKGAPGEKGPQGPAGR---DGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKG 1174 Query: 2262 ERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGP 2321 E+G GP G +G G+PGP G G GPRG+ G G++G +G RGFPG PGP Sbjct: 1175 EQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQ--------GLFGQKGDEGPRGFPGPPGP 1226 Query: 2322 KGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 G G PG G G G G+ G GPPG G G PG GP GP G G+ Sbjct: 1227 VGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGN 1277 Score = 272 bits (695), Expect = 4e-72 Identities = 159/378 (42%), Positives = 188/378 (49%), Gaps = 44/378 (11%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDG---YRGYPGD---------------EGGPGERGPPGVN 2079 G G G G GP G+PG+DG RG+PGD EG PG GP G Sbjct: 1030 GLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSP 1089 Query: 2080 GTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDK 2139 G +G G G G+ G G G G GE G G G G G G G G PG G Sbjct: 1090 GERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPV 1149 Query: 2140 GPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGG 2199 GP GE G++G++G G G+ G D E+GP G TG GP+G PG G G PG G+ G Sbjct: 1150 GPPGEDGDKGEIGEPGQKGSKG-DKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGL 1208 Query: 2200 FGRR---------GPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGP 2250 FG++ GPPG G +G PG PG +GE G G GP GP GP G G G GP Sbjct: 1209 FGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGP 1268 Query: 2251 RGSGGAAGAP---GERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG------- 2300 +G G G P GE+G G G G PGE GP G G RG +GE+G G G Sbjct: 1269 QGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGP 1328 Query: 2301 VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDP-- 2358 G +G +G G GFPG PGP G PG G +G G KG G G +G PG G+ G Sbjct: 1329 PGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGP 1388 Query: 2359 ----GYPGPAGPKGNRGD 2372 G PGPAGP+G +G+ Sbjct: 1389 PGKRGPPGPAGPEGRQGE 1406 Score = 271 bits (693), Expect = 8e-72 Identities = 158/365 (43%), Positives = 187/365 (51%), Gaps = 42/365 (11%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G +GDRG IG GP+G G +G +G G G PG GPPG G G G PG Sbjct: 823 GIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPG-------- 874 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157 +PG +G G IG G G +G+KG G+ G+ G G+RG GPRGE+G RG G G Sbjct: 875 -YPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPK 933 Query: 2158 GNPGQDSQ-----ERGPKGETGDLG------PMGVPGRDGVPGGPGETGKNGGFGRRGPP 2206 GN G D ERGP G G G P G PG+DG+PG PG+ G+ G G+ GPP Sbjct: 934 GNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPP 993 Query: 2207 GAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGA------- 2259 G G G G G G G RG GP GP G GL G G G +G G AG Sbjct: 994 GPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPP 1053 Query: 2260 -----PGERGRTGPL------GRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRR 2307 PG+RG GP+ G +G PG PGP G G RGP G G G G G +G Sbjct: 1054 GLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPP 1113 Query: 2308 GKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPK 2367 G GE+G PG GP+G G GL GP G+ G G GPPG G KG+ G PG G K Sbjct: 1114 GPAGEKGAPGEKGPQGPAGRDGLQ---GPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSK 1170 Query: 2368 GNRGD 2372 G++G+ Sbjct: 1171 GDKGE 1175 Score = 271 bits (692), Expect = 1e-71 Identities = 157/339 (46%), Positives = 178/339 (52%), Gaps = 17/339 (5%) Query: 2040 RGDRGPIGSIG---PKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096 RG GP+G G P G PG G +G PGD G G RG G G G G G+ G G+ Sbjct: 558 RGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGA 617 Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGD 2156 RG PG+ G G+ G DGL G G+KG G G G PG GD G RG+ GE VG RG Sbjct: 618 RGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGE---VGPRGL 674 Query: 2157 PGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPG 2216 PG P GP+G G GP G PG GV G G+ G G G +G PG G +G PG Sbjct: 675 PGEP-------GPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPG 727 Query: 2217 QPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPG 2276 G G QG G G GP G PGL G G GP G G G PGE+G GP G +G G Sbjct: 728 AQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIG 787 Query: 2277 EPGP---KGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGLNG 2332 PGP KG G RG +G G+ G DG G +G G KG+RG G PGP+G G G G Sbjct: 788 YPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKG 847 Query: 2333 TTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 GP G G G G G +G G PGYPG GPKG+ G Sbjct: 848 RGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIG 886 Score = 270 bits (689), Expect = 2e-71 Identities = 166/388 (42%), Positives = 192/388 (49%), Gaps = 50/388 (12%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNG---TQGFQGCPG 2089 P +G+ G GP GS G KG PG+ G +G G +G PG G PG G + G +G PG Sbjct: 563 PMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPG 622 Query: 2090 QRGVKGSRGF------PGEKGEVGEIGLDGL------DGEDGDKGLPGSSGEKGNPGRRG 2137 Q G KG RGF PGEKG G+ G G DGE GD G G G G PG RG Sbjct: 623 QTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRG 682 Query: 2138 DKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVP---GGPGET 2194 GP+G G G G+ G G PG GP+GE G G G PG G+P G G Sbjct: 683 LLGPKGPPGPPGPPGVTGMDGQPGPKGNV-GPQGEPGPPGQQGNPGAQGLPGPQGAIGPP 741 Query: 2195 GKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSG 2254 G+ G G+ G PG G G PG PG EG G +G QGP GP GP G G +G+ G G Sbjct: 742 GEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIR 801 Query: 2255 GAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGS----------- 2303 G G GE+G G G KG+ G G +G IG GPRGE G +G G G Sbjct: 802 GLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPP 861 Query: 2304 --------------EGRRGKKGERGFPGYPGP------KGNPGEPGLNGTTGPKGIRGRR 2343 GR+G KG GFPG+PG +G PG+PG G GP G RG R Sbjct: 862 GEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGER 921 Query: 2344 GNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 G G G G KG+ G GPAGP G RG Sbjct: 922 GPRGITGKPGPKGNSGGDGPAGPPGERG 949 Score = 268 bits (684), Expect = 8e-71 Identities = 168/391 (42%), Positives = 195/391 (49%), Gaps = 60/391 (15%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G +G GP G GP G PGE G G PG G PG +GP G+ GF G PG G KG R Sbjct: 844 GPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGP---KGSIGFPGFPGANGEKGGR 900 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGN---------PGRRGDKGPRGE---- 2144 G PG+ G G+ G G GE G +G+ G G KGN PG RG GP+G Sbjct: 901 GTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFP 960 Query: 2145 --KGERGDVGIRGDPGNPGQDSQER--------------GPKGETGDLGPMGVPGRDGVP 2188 KG G G G PG+PGQ + GP+G TG+ GPMG G G P Sbjct: 961 GPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPP 1020 Query: 2189 GGPGE------TGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQ---------GTRGAQGPA 2233 G PGE GK G G GP G G G PG GF G++ G +G +GP Sbjct: 1021 GPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPP 1080 Query: 2234 GPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGET 2293 GP GP G GE+G +G G G G PG +G GP G KG PGE GP+G G G +G Sbjct: 1081 GPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPV 1140 Query: 2294 GDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNS------ 2346 G G G VG G G KGE G PG G KG+ GE G G TGP+G G+ G S Sbjct: 1141 GLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEP 1200 Query: 2347 ---GPPGIVGQKGDP---GYPGPAGPKGNRG 2371 G G+ GQKGD G+PGP GP G +G Sbjct: 1201 GPRGQQGLFGQKGDEGPRGFPGPPGPVGLQG 1231 Score = 229 bits (584), Expect = 3e-59 Identities = 133/304 (43%), Positives = 160/304 (52%), Gaps = 25/304 (8%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G G++G G G G+PGE G G G+ G GE GP G G G +G PG G KGS Sbjct: 1279 GAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSP 1338 Query: 2098 G---FPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154 G FPG+ G GE G G DG GDKG G G+ G+PG G+ GP G G+RG G Sbjct: 1339 GPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPA 1398 Query: 2155 GDPGNPGQDSQE-----RGPKGETGDLGPMGVPGR---DGVPGGPGETGKNGGFGRRGPP 2206 G G G+ + GP G+TG +GP G PG+ DG+ G PG G+ G G GP Sbjct: 1399 GPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPD 1458 Query: 2207 GAKGNKGGPGQPGFEGEQGTRGAQGPAGPAG---PPGLIGEQGISGPRGSGGAAGAPGER 2263 G G G PG PG +G+ G +G +G G G PPG GE+G G G G++G GE+ Sbjct: 1459 GPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQ 1518 Query: 2264 GRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKG 2323 G TGP G G PG PG G G +G + GS G G KGE G PG PGP G Sbjct: 1519 GITGPSGPIGPPGPPGLPGPPGPKGAK-----------GSSGPTGPKGEAGHPGPPGPPG 1567 Query: 2324 NPGE 2327 PGE Sbjct: 1568 PPGE 1571 Score = 194 bits (492), Expect = 2e-48 Identities = 137/343 (39%), Positives = 158/343 (46%), Gaps = 39/343 (11%) Query: 2057 EDGYRGYPGDEGGPGERGPPGVNGTQG--FQGCPGQRGVKGSRGFPG--EKGEVGEIGLD 2112 E+ Y Y P E GP G+ Q ++G G RG KG +G P E G + ++ Sbjct: 414 ENYYDPYYDPTSSPSEIGP-GMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGML----IE 468 Query: 2113 GLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQ---ERGP 2169 G G +G GLPG G G G+ GD G RG G G G G PG PG G Sbjct: 469 GPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGG 528 Query: 2170 KGETGDLGPMGVPGRDGVPGG---------PGETGKNGGFGRRGPPGAKGNKGGPGQPGF 2220 G+ G GPM V ++ G G G GR GP G G+ G G+PG Sbjct: 529 GGDAGSKGPM-VSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGD 587 Query: 2221 EGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGE--- 2277 G QG RG QGP GPAG PG G G G RG G G G+RG G G GE G Sbjct: 588 VGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGD 647 Query: 2278 ------PGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLN 2331 PGP G G RG GE G G G G RG G +G PG PGP PG G++ Sbjct: 648 PGPSGPPGPPGDDGERGDDGEVGPRGLP--GEPGPRGLLGPKGPPGPPGP---PGVTGMD 702 Query: 2332 GTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGP---AGPKGNRG 2371 G GPKG G +G GPPG G G G PGP GP G +G Sbjct: 703 GQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKG 745 Score = 165 bits (417), Expect = 8e-40 Identities = 133/387 (34%), Positives = 158/387 (40%), Gaps = 78/387 (20%) Query: 2054 IPGEDGYRGYPGDE--GGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGL 2111 +P ED Y P D+ G GE P P + P G L Sbjct: 341 VPSEDYYTPSPYDDLTYGEGEENPDQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDL 400 Query: 2112 DGLDGEDGDKGL----------PGSSGEKGNPGR--------RGDKGPRGEKGERGDVGI 2153 +G E+ + L P SS + PG G GPRGEKG++G+ I Sbjct: 401 EGEFTEETIRNLDENYYDPYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAI 460 Query: 2154 RGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKG 2213 PG + GP G G G G PG G G G+ G+ G GR G PGA G G Sbjct: 461 I----EPGMLIE--GPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPG 514 Query: 2214 GPGQ----PGFEGEQGTRGAQGPA--------------------GPAGPPGLIGEQGISG 2249 PG P G G G++GP GPAGP GL G G G Sbjct: 515 PPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVG 574 Query: 2250 PRGSGGAAGAPGERGRTGPLG------------RKGEPGEPGPKGGIGNRGPRGETGDDG 2297 P GSGG G PG+ G GP G R+G G G +G G GP+G+ G DG Sbjct: 575 PPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDG 634 Query: 2298 RDGV-GSEGRRGKKGERGFPGYPGP------------KGNPGEPGLNGTTGPKGIRGRRG 2344 G+ G +G RG G G PG PG +G PGEPG G GPK G G Sbjct: 635 LAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPK---GPPG 691 Query: 2345 NSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 GPPG+ G G PG G GP+G G Sbjct: 692 PPGPPGVTGMDGQPGPKGNVGPQGEPG 718 Score = 52.8 bits (125), Expect = 5e-06 Identities = 27/63 (42%), Positives = 31/63 (49%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRG 2092 P SG +G++G G GP G PG G G PG +G G GP G G G G PG G Sbjct: 1508 PQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPG 1567 Query: 2093 VKG 2095 G Sbjct: 1568 PPG 1570 >gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] Length = 1860 Score = 296 bits (758), Expect = 2e-79 Identities = 164/342 (47%), Positives = 189/342 (55%), Gaps = 10/342 (2%) Query: 2038 GQRGDRGPIGSIGPKG---IPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094 G RG GP+G +G KG PG G G+PGD G PG+ GP G+ G G +G PG RG Sbjct: 883 GARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQL 942 Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154 G G G G G GL+G G G G PG G KG PG G GP GE+G G +G+ Sbjct: 943 GPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLV 1002 Query: 2155 GDPGNPGQ--DSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPG---AK 2209 G+PG G+ D GP G G G MG PG G G PGE G G G RGPPG AK Sbjct: 1003 GEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAK 1062 Query: 2210 GNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPL 2269 G +G G G GEQG+RG +GP GP G PG G+QG++G RG G+ G PG G +GP Sbjct: 1063 GRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPP 1122 Query: 2270 GRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPG 2329 G KG PGEPGP+G G GP GE G G G+ G G GE G G GP G PGE G Sbjct: 1123 GTKGLPGEPGPQGPQGPIGPPGEMGPKGPP--GAVGEPGLPGEAGMKGDLGPLGTPGEQG 1180 Query: 2330 LNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 L G G G+ G G GP G+ G +GDPG G G KG G Sbjct: 1181 LIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEG 1222 Score = 277 bits (709), Expect = 1e-73 Identities = 165/397 (41%), Positives = 201/397 (50%), Gaps = 58/397 (14%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNG------TQGFQGCPGQR 2091 G +G RGP G GP G G G +G PG +G PG G GV G ++GF G PG Sbjct: 1060 GAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPS 1119 Query: 2092 GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGR---RGDKGPRGEKGER 2148 G G++G PGE G G G G GE G KG PG+ GE G PG +GD GP G GE+ Sbjct: 1120 GPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQ 1179 Query: 2149 GDVGIRGDPGNPGQ-----------DSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKN 2197 G +G RG+PG G D + GP GE G+ G G+ G DG PG PG TG Sbjct: 1180 GLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVR 1239 Query: 2198 GGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAA 2257 G G+ G G KG G G G++G+ G G G GP G PG G +G GP G+ G Sbjct: 1240 GPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRM 1299 Query: 2258 GAPGERGRTG---------------PLGRKGE----------PGEPGPKGGIGNRGPRGE 2292 GA GE G G P G KGE PG PG +G +G+RG RGE Sbjct: 1300 GAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGE 1359 Query: 2293 TGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKG------------I 2339 GD G G G +G RGK G++G PG+PGP+G PG G G GPKG + Sbjct: 1360 PGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGV 1419 Query: 2340 RGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQ 2376 +G +G GP G+VG++G G GP G G G + Q Sbjct: 1420 QGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQ 1456 Score = 277 bits (708), Expect = 1e-73 Identities = 162/367 (44%), Positives = 200/367 (54%), Gaps = 33/367 (8%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G +GD G G G G PG G++GYPG G PGE+G PG G+ G +G PG++G+ G Sbjct: 688 GAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPV 747 Query: 2098 GFPGEKGEVGEIGLD---GLDGEDGDKGLPGSSGEKGN------PGRRGDKGPRGEKGER 2148 G PG KG G IGL GL G DG++GLPG G++G PG G++GP G G Sbjct: 748 GDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNP 807 Query: 2149 GDVGIRGDPGNPGQDSQ--------ERGPKGETGDLGPMGVP------GRDGVPGGPGET 2194 G++G+ G PG PG GPKG G +G +G P G GVPG G+ Sbjct: 808 GELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDP 867 Query: 2195 GKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGP---R 2251 G G G +G PG G +G PG G G++G+ G GP GP G PG IG G +GP + Sbjct: 868 GFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMK 927 Query: 2252 GSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV----GSEGRR 2307 G GA G PG RG+ GP G +G G PG G G G +G G G DGV G GR Sbjct: 928 GKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRP 987 Query: 2308 GKKGERGFPGYPGPKGNP---GEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPA 2364 G GE+GF G+ G G P GE G G GP G+ G +G+ G PG+ G G PG PGP Sbjct: 988 GPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQ 1047 Query: 2365 GPKGNRG 2371 GP G+RG Sbjct: 1048 GPPGSRG 1054 Score = 276 bits (707), Expect = 2e-73 Identities = 159/363 (43%), Positives = 190/363 (52%), Gaps = 29/363 (7%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRG 2092 P G G+ GP G GP G PGE G +G PG G PG G G+ G G G PG++G Sbjct: 1121 PPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQG 1180 Query: 2093 VKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVG 2152 + G RG PG +G+ G +G DGL G+ GD G G GEKG G G+ GP G G G G Sbjct: 1181 LIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRG 1240 Query: 2153 IRGDPGNPGQDSQ--ERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKG 2210 G G G+ + +G KG G LG MGVPG G PG PG G G GP GA G Sbjct: 1241 PEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSL---GPTGAPG 1297 Query: 2211 NKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLG 2270 G G+PG G G +G GP GP GP G GEQG G + G G PG+RG G G Sbjct: 1298 RMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGK--AEGPPGPPGDRGPVGDRG 1355 Query: 2271 RKGEPGEPGPKGGIGNRGPRGETGDDGRDG-------------VGSEGRRGKKGERGFP- 2316 +GEPG+PG G G +G RG+ G G+ G G+EG +GK+G+ G P Sbjct: 1356 DRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPG 1415 Query: 2317 --------GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKG 2368 G PGP+G G GL G GP G+ GR G +G G G GDPG GPAG +G Sbjct: 1416 RRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRG 1475 Query: 2369 NRG 2371 N G Sbjct: 1476 NPG 1478 Score = 274 bits (701), Expect = 9e-73 Identities = 162/399 (40%), Positives = 205/399 (51%), Gaps = 69/399 (17%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRG---VK 2094 G+ G +GP G++G G+PGE G +G G G PGE+G G G G +G G G +K Sbjct: 1144 GEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLK 1203 Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPG---------SSGEKGNPGRRGDKGPRGEK 2145 G RG PG GE GE G +GL GEDG G PG SG++G GR G KG +G + Sbjct: 1204 GDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQ 1263 Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPG------------- 2192 G+ G++G+ GDPG PG GPKG G LGP G PGR G G PG Sbjct: 1264 GQLGEMGVPGDPGPPGTP----GPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGP 1319 Query: 2193 --------ETGKNGGFGR----------RGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAG 2234 E G+ G G+ RGP G +G++G PG PG+ G++G +G +G G Sbjct: 1320 LGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPG 1379 Query: 2235 PAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGE---PGPKGGIGNRG--- 2288 G PG G +G GP+GS GA G G++G+ G GR+G G PGP+G +G +G Sbjct: 1380 QQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEG 1439 Query: 2289 ---------------PRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNG 2332 +GE GDDG G +G G+RG G G PG GP G GE GL G Sbjct: 1440 IAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPG 1499 Query: 2333 TTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 GP G RG G +G PG G+ G G PG +G G G Sbjct: 1500 QLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPG 1538 Score = 272 bits (695), Expect = 4e-72 Identities = 151/343 (44%), Positives = 184/343 (53%), Gaps = 23/343 (6%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G++GDRG +GP G+PG G G+PG GG G G PG G G +G PG RG KG R Sbjct: 1009 GEKGDRG---MMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRR 1065 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKG---ERGDVGIR 2154 G G G GE G GL G G +G PG G++G G RG G RG G G G + Sbjct: 1066 GPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTK 1125 Query: 2155 GDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGG 2214 G PG PG + GP G G++GP G PG G PG PGE G G G G PG +G G Sbjct: 1126 GLPGEPGPQGPQ-GPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQ 1184 Query: 2215 PGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGE 2274 G+PG EG+ +GP GP GL G++G GP G GE+G+ G +G G Sbjct: 1185 RGEPGLEGD---------SGPMGPDGLKGDRGDPGPDGE------HGEKGQEGLMGEDGP 1229 Query: 2275 PGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGT 2333 PG PG G G G G+ G+ GR G G++G +G+ GE G PG PGP G PG G G+ Sbjct: 1230 PGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGS 1289 Query: 2334 TGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQ 2376 GP G GR G G PG+ G G G GP GP G +G+ +Q Sbjct: 1290 LGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQ 1332 Score = 268 bits (685), Expect = 6e-71 Identities = 165/401 (41%), Positives = 199/401 (49%), Gaps = 50/401 (12%) Query: 2021 LDNIAEKACCGVPCKCS--GQRGDRGPIGSIGPKGIPGEDGYRGYPGD------EGGPGE 2072 L + +K G P G GD GP G GP+G+ G+ G RG PG EG G Sbjct: 891 LGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGP 950 Query: 2073 RGPPGVNGTQG------FQGCPGQRGVKGSRGFPGEKGEVGE---------IGLDGLDGE 2117 GPPG G +G F G PG GVKG G PG G VGE +G G+ GE Sbjct: 951 MGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGE 1010 Query: 2118 DGDKGL------PGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE----- 2166 GD+G+ PG G G+PG G G GE G +G G RG PG G + Sbjct: 1011 KGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGP 1070 Query: 2167 RGPKGETGDLGPMGVPGRDGVPGGPGE---TGKNGGFGRR------GPPGAKGNKGGPGQ 2217 GP GE G G G PG G PG PG+ G+ G G R GP G G KG PG+ Sbjct: 1071 DGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGE 1130 Query: 2218 PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGE 2277 PG +G QG G G GP GPPG +GE G+ G G G G G G G +G++GEPG Sbjct: 1131 PGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGL 1190 Query: 2278 PGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYP------GPKGNPGEPGL 2330 G G +G G +G+ GD G DG G +G+ G GE G PG P GP+G G+ G Sbjct: 1191 EGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGE 1250 Query: 2331 NGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 G TG KG +G +G G G+ G G PG PGP G +G+ G Sbjct: 1251 KGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLG 1291 Score = 258 bits (658), Expect = 9e-68 Identities = 153/366 (41%), Positives = 189/366 (51%), Gaps = 31/366 (8%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096 SG++G++G G+ G KG G+ G G PGD G PG GP G G+ G G PG+ G +G Sbjct: 1245 SGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGE 1304 Query: 2097 ---RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSS-GEKGNPGRRGDKGPRGEKGERGDVG 2152 G+ G KG VG +G G GE G++G G + G G PG RG G RG++GE GD G Sbjct: 1305 PGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPG 1364 Query: 2153 ---------IRGDPGNPGQDSQER-----GPKGETGDLGPMGVPGRDGVPG--------- 2189 +RG PG GQ GPKG G GP G G+ G PG Sbjct: 1365 YPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQG 1424 Query: 2190 --GP-GETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQG 2246 GP G G+ G G GP G G G GQ G +G+ G G GPAG G PG+ G G Sbjct: 1425 LPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPG 1484 Query: 2247 ISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEG 2305 GP G G +G PG+ G G G +G G PG +G G++G G++G+ G G+ G G Sbjct: 1485 AQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFG 1544 Query: 2306 RRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAG 2365 +G G+ GF G GP+G PG G G GP GI G G GP G G +GD G GP G Sbjct: 1545 PKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRG 1604 Query: 2366 PKGNRG 2371 P G RG Sbjct: 1605 PPGPRG 1610 Score = 255 bits (651), Expect = 6e-67 Identities = 154/371 (41%), Positives = 191/371 (51%), Gaps = 49/371 (13%) Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEG---GPGERGPPGVNGTQGFQGC 2087 G+P G RG RGP G G G+PG G +G GD G G G G G G G Sbjct: 646 GIP----GARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGN 701 Query: 2088 PGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGE 2147 PG G KG +G+PG G GE G G +G G KG P G +G PG GD GP+G +G Sbjct: 702 PGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYP---GRQGLPGPVGDPGPKGSRGY 758 Query: 2148 RGDVGI---------RGDPGNPGQDSQ-----------ERGPKGETGDLGPMGVPGRDGV 2187 G G+ RG PG PG+ + ERGP G G+ G +G+PG GV Sbjct: 759 IGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGV 818 Query: 2188 PGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGI 2247 PG G+ G G G GP G KG G G+PG +G++G +G PG+ G+ G Sbjct: 819 PGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGV---------PGVSGDPGF 869 Query: 2248 SGPRGSGGAAGAPGERGRTGPLGRKGE------PGEPGPKGGIGNRGPRGETGDDGRDG- 2300 G +GS G G PG RG+ GPLG+ G+ PG PGP+G G+ GP G+ G +G G Sbjct: 870 QGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGK 929 Query: 2301 VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGY 2360 G+ G G +G+ G G GP G PG PGL G G KG GR G G+ G+ GDPG Sbjct: 930 PGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGR---PGLDGVKGEPGDPGR 986 Query: 2361 PGPAGPKGNRG 2371 PGP G +G G Sbjct: 987 PGPVGEQGFMG 997 Score = 237 bits (605), Expect = 1e-61 Identities = 142/340 (41%), Positives = 173/340 (50%), Gaps = 19/340 (5%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQG-------CPGQ 2090 G RG GP G+ G G GE G GY G +G G GPPG G +G QG PG Sbjct: 1285 GSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGP 1344 Query: 2091 RGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD 2150 G +G G G++GE G+ G G +G G +G PG G+ G+PG RG GP+G KG G Sbjct: 1345 PGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGP 1404 Query: 2151 VGIRGDPGNPGQDSQER-----GPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP 2205 G +G G PG+ + GP+G G G G+ G DG+PG G+ G+ G G G Sbjct: 1405 KGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGD 1464 Query: 2206 PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGR 2265 PG G G G PG G GAQGP G G GL G+ G G RG+ G G PG +G Sbjct: 1465 PGPMGPAGKRGNPGVAG---LPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGE 1521 Query: 2266 TGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV----GSEGRRGKKGERGFPGYPGP 2321 G G+ G+ GE G G G GP+G GD G G+ G G GK+G G G GP Sbjct: 1522 PGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGP 1581 Query: 2322 KGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYP 2361 G PG G G+ G G++G RG GP G G G PG P Sbjct: 1582 SGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGP 1621 Score = 176 bits (446), Expect = 3e-43 Identities = 115/275 (41%), Positives = 138/275 (50%), Gaps = 38/275 (13%) Query: 2127 SGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDG 2186 +G P G GP+G+ G G G+ G PG PG RGP+G GP G PG G Sbjct: 615 AGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPG----ARGPRGPP---GPYGNPGLPG 667 Query: 2187 VPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQG 2246 PG G+ G G + GAKG+ G PG G G G +G +G GPAG P GEQG Sbjct: 668 PPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHP---GEQG 724 Query: 2247 ISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEG 2305 GP GS GA G PG +G GP+ G+PG G +G IG G G G DG G+ G G Sbjct: 725 QPGPEGSPGAKGYPGRQGLPGPV---GDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPG 781 Query: 2306 RRGKKGERGFPGY------PGPKGNPGEPGLNGT------------------TGPKGIRG 2341 +RGK G GFPG PG GNPGE GL G GPKG++G Sbjct: 782 KRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKG 841 Query: 2342 RRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQ 2376 G+ G PG+ G KG+ G PG +G G +GD Q Sbjct: 842 LMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQ 876 Score = 152 bits (385), Expect = 4e-36 Identities = 96/237 (40%), Positives = 120/237 (50%), Gaps = 35/237 (14%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEG--------GP-GERGPPGVNGTQGFQGCP 2088 G G +G G GP G+PG DG G G++G GP G+RG PGV G G QG P Sbjct: 1430 GVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPP 1489 Query: 2089 G---QRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEK 2145 G + G+ G G PG++G G GL G GE G KG PG SGE G PG G GP+G Sbjct: 1490 GFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPP 1549 Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGF---GR 2202 G+ G GI+G G PG G+ G +GP+G+ G G+PG G+ G G + G Sbjct: 1550 GDIGFKGIQGPRGPPGL-------MGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGP 1602 Query: 2203 RGPPGAKGNKGGPGQPG-------------FEGEQGTRGAQGPAGPAGPPGLIGEQG 2246 RGPPG +G G PG PG F+ T GA P + P L+ +QG Sbjct: 1603 RGPPGPRGRPGPPGPPGGPIQLQQDDLGAAFQTWMDTSGALRPESYSYPDRLVLDQG 1659 Score = 48.5 bits (114), Expect = 1e-04 Identities = 40/151 (26%), Positives = 62/151 (41%), Gaps = 13/151 (8%) Query: 2844 PTKNLVKFGHKQVNVPNNVTSSPTSNPVTTTKPVTTTKPVTTTT---KPVTTTTKPVTII 2900 PT+ + +P PTS PV KP+ +P +T+P+ Sbjct: 387 PTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPAEKPIQRNPGMPRPPPPSTRPLPPT 446 Query: 2901 NQPSVKPA---AAKPAPAKPVAAKPVATKMATVRPP--VAVKPATAAKPVAAK----PAA 2951 S KP A A A+KP + + +T +PP A+ + A P + + PA Sbjct: 447 TSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSPAPTPGSTRSTRPPAT 506 Query: 2952 VRPPAAAAAKPVATKPEVPRPQAAKPAATKP 2982 + PP + + P T P VP P +A + KP Sbjct: 507 MVPPTSGTSTP-RTAPAVPTPGSAPTGSKKP 536 Score = 45.1 bits (105), Expect = 0.001 Identities = 42/156 (26%), Positives = 64/156 (41%), Gaps = 28/156 (17%) Query: 2869 NPVTTTKPVTTTKPVTTTT----KPVTTTTKPVTIINQPSVKPAAA-----KPAPAKPVA 2919 NP P +T+P+ TT KP+ T + I + KPA+A KP P ++ Sbjct: 429 NPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALS 488 Query: 2920 AKPVATKMAT--VRPPVAVKPATAAKPVAAKPAAVRPPAAA---AAKPVAT--------- 2965 + P T +T RPP + P T+ AV P +A + KP+ + Sbjct: 489 SSPAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEASKKAGPK 548 Query: 2966 ----KPEVPRP-QAAKPAATKPATTKPMVKMSREVQ 2996 KP RP +AA+ TT+P + + Q Sbjct: 549 SSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQ 584 Score = 39.3 bits (90), Expect = 0.063 Identities = 35/132 (26%), Positives = 53/132 (40%), Gaps = 19/132 (14%) Query: 2863 TSSPTSNPVTTTKPVTTTKPVTTTTKPVTTTTKPVTIINQPSVK--PAAAKPAPAKP--V 2918 T P S P + P T+ P+ + T T P+ K P ++P PA+ Sbjct: 362 TKIPKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRP 421 Query: 2919 AAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPPAAAAAKPVATKPEVP---RPQAA 2975 A KP+ RPP P+T P P +++ KP+ T A+ Sbjct: 422 AEKPIQRNPGMPRPP---PPSTRPLP---------PTTSSSKKPIPTLARTEAKITSHAS 469 Query: 2976 KPAATKPATTKP 2987 KPA+ + +T KP Sbjct: 470 KPASARTSTHKP 481 Score = 38.1 bits (87), Expect = 0.14 Identities = 33/123 (26%), Positives = 49/123 (39%), Gaps = 17/123 (13%) Query: 2867 TSNPVTTTKPVTTTKPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPVA--AKPVA 2924 +S+P T +T+P T P + T+ P T P+ P +A KP+ A A Sbjct: 488 SSSPAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPT--PGSAPTGSKKPIGSEASKKA 545 Query: 2925 TKMATVRPPVAVKPATAAKPVAAKPAAVRP------------PAAAAAKPVATKPEVPRP 2972 ++ R PV ++P AA+ V RP PA A P PRP Sbjct: 546 GPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLA-PAQFLSSSPRP 604 Query: 2973 QAA 2975 ++ Sbjct: 605 TSS 607 Score = 35.8 bits (81), Expect = 0.69 Identities = 34/151 (22%), Positives = 54/151 (35%), Gaps = 11/151 (7%) Query: 2870 PVTTTKPVTTTKPVTTTTKPVTTTTK-PVTIINQPSVKPAAAKPAPAKPVAAKPVATKMA 2928 P + T +P T TK P ++ +PS + P + K + Sbjct: 338 PASVGGSTRTPRPAAAQPSQKITATKIPKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFT 397 Query: 2929 TVRPPVAVKPATAAKPVAAKPAAVRPPAAAAAKPVATKPEVPRPQAAKPAATKPATT--- 2985 P + ++PV PA V P A KP+ P +PRP P T+ Sbjct: 398 KSALPTQKQVPPTSRPV---PARVSRP---AEKPIQRNPGMPRPPPPSTRPLPPTTSSSK 451 Query: 2986 KPMVKMSR-EVQVFEITENSAKLHWERAEPP 3015 KP+ ++R E ++ A +PP Sbjct: 452 KPIPTLARTEAKITSHASKPASARTSTHKPP 482 Score = 35.4 bits (80), Expect = 0.91 Identities = 30/120 (25%), Positives = 46/120 (38%), Gaps = 23/120 (19%) Query: 2865 SPTSNPVTTTKPVTTTKPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPVAAKPVA 2924 +PT +T+P T P T+ T + P PA P A + KP+ Sbjct: 492 APTPGSTRSTRPPATMVPPTSGT-------------STPRTAPAVPTPGSAPTGSKKPIG 538 Query: 2925 TKMATVRPPVAVKPATAAKPVAAKPAAVRPPAAAAAKPVATKPEVPRPQAAKPA-ATKPA 2983 ++ + P K KP +RP AA P++ P P+ +P+ T PA Sbjct: 539 SEASKKAGP---------KSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPA 589 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 293 bits (749), Expect = 2e-78 Identities = 164/373 (43%), Positives = 194/373 (52%), Gaps = 43/373 (11%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096 +G G GP G G +G PG G++G PG G PGE G PG G G G PG G +G Sbjct: 641 AGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGE 700 Query: 2097 RGFPGEKGEVGEIGLDG------LDGEDGDKGLPGSSGE---------KGNPGRRGDKGP 2141 RGFPGE+G G GL G G DG KG G +G +G PG RG G Sbjct: 701 RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 760 Query: 2142 RGEKGERGDVGIRGDPGNPGQDSQE--------------RGPKGETGDLGPMGVPGRDGV 2187 G KG+RGDVG +G G PG+D G KGE G GP G G G Sbjct: 761 AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA 820 Query: 2188 PGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGI 2247 PG GETG G G GPPGA G G G+ G G++G GA GP GP+G PG G G+ Sbjct: 821 PGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGV 880 Query: 2248 SGPRGSGGAAGAPGERG------RTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV 2301 +GP+G+ GA G PG G R GP G G PG PGP G G GP+G GD Sbjct: 881 TGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDS----- 935 Query: 2302 GSEGRRGKKGERGFPGYPGPKGNPGE---PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDP 2358 G GR G+ G +G G PG KG PG+ G G GP+G+ G+RG G PG G++G P Sbjct: 936 GPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFP 995 Query: 2359 GYPGPAGPKGNRG 2371 G PGP+G G +G Sbjct: 996 GLPGPSGEPGKQG 1008 Score = 290 bits (742), Expect = 2e-77 Identities = 166/361 (45%), Positives = 189/361 (52%), Gaps = 38/361 (10%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G+ G GP+G GP G PG+ G G G G GERGPPG G +GF G PG GVKG R Sbjct: 231 GEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHR 290 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157 G+PG G GE G G+ GE G S GE G+PG G +G GE+G G G G Sbjct: 291 GYPGLDGAKGEAGAPGVKGESG------SPGENGSPGPMGPRGLPGERGRTGPAGAAGAR 344 Query: 2158 GNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQ 2217 GN GQ GP G G +GP G PG G PG GE G G RGP GA+G +G PG Sbjct: 345 GNDGQP----GPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGA---RGPEGAQGPRGEPGT 397 Query: 2218 PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGE 2277 PG G G G G G G G G GI+G G G G PG +G TGPLG KG+ GE Sbjct: 398 PGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGE 457 Query: 2278 PGPKGGIGNRGPRGETGDDGRDG----VGSEGRRGKKGE------------------RGF 2315 PG G G +GP+GE G G G G EG+RG +GE RGF Sbjct: 458 PGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGF 517 Query: 2316 P---GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 P G GPKG PGE G +G GPKG G G G PG+ G +G G PG AGP+G G Sbjct: 518 PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGP 577 Query: 2373 S 2373 S Sbjct: 578 S 578 Score = 283 bits (723), Expect = 2e-75 Identities = 173/406 (42%), Positives = 202/406 (49%), Gaps = 74/406 (18%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGG------------------PGERGPPGV 2078 +G+ GD GP G +GP G PGEDG G PG +G PG+ G G+ Sbjct: 563 TGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGL 622 Query: 2079 NGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGD 2138 G G +G PG+ G G+ G PG G GE G G G G +GLPG G G G+ GD Sbjct: 623 PGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGD 682 Query: 2139 K------------GPRGEK---GERGDVGI------RGDPGNPGQDSQERGPKGETGDLG 2177 + GPRGE+ GERG G RG PG PG D GPKG +G G Sbjct: 683 QGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTD----GPKGASGPAG 738 Query: 2178 PMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAG 2237 P G G G+ G PGE G G G +G G G KG G PG +G +G G GP GPAG Sbjct: 739 PPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAG 798 Query: 2238 PPGLIGEQGISGPRGSGGAAGAPGERGRTGP---------------LGRKGEPGEPGPKG 2282 G GE G GP GS GA GAPGERG TGP G KGE GE G KG Sbjct: 799 ANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKG 858 Query: 2283 GIGNRGPRGETGDDGRDG-------VGSEGRRGKKGERGFPGY------PGPKGNPGEPG 2329 G GP+G +G G G G+ G +G G GFPG PG GNPG PG Sbjct: 859 DAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG 918 Query: 2330 LNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSID 2375 G +G G +G RG+SGPP G+ G+PG GPAGP G +G+ D Sbjct: 919 PPGPSGKDGPKGARGDSGPP---GRAGEPGLQGPAGPPGEKGEPGD 961 Score = 279 bits (713), Expect = 4e-74 Identities = 158/349 (45%), Positives = 180/349 (51%), Gaps = 12/349 (3%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096 +G G RG G GP G PG G G PG G PG +G G G +G +G G RG G+ Sbjct: 338 AGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGT 397 Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGD 2156 G PG G G G DG+ G G G PG +G G PG RG GP+G G G G G+ Sbjct: 398 PGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGE 457 Query: 2157 PGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPG---AKGNKG 2213 PG G E+GPKGE G GP G PG G G G G+ GG G GPPG A GN+G Sbjct: 458 PGIAGFKG-EQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRG 516 Query: 2214 GPGQPGFEGEQGTRGAQGPAGPAGP------PGLIGEQGISGPRGSGGAAGAPGERGRTG 2267 PGQ G G +G G +GP+G AGP PG GE G+ G RG G G G +G+ G Sbjct: 517 FPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVG 576 Query: 2268 PLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGE 2327 P G GE G PGP G G RG G G G G + G GK GE+G PG PG +G PG+ Sbjct: 577 PSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKG--ANGEPGKAGEKGLPGAPGLRGLPGK 634 Query: 2328 PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQ 2376 G G GP G G G G G G G G PGP GP G G DQ Sbjct: 635 DGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQ 683 Score = 276 bits (706), Expect = 2e-73 Identities = 171/406 (42%), Positives = 200/406 (49%), Gaps = 63/406 (15%) Query: 2031 GVPCKCSGQRGDRGPIGSIG---PKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGC 2087 G P K +G+RG GP G+ G G+PG G+RGYPG +G GE G PGV G G G Sbjct: 258 GKPGK-AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGE 316 Query: 2088 PGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGE---------KGNPGRRGD 2138 G G G RG PGE+G G G G G DG G G G G PG +G+ Sbjct: 317 NGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGE 376 Query: 2139 KGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNG 2198 GP G +G G G RG+PG PG GP G +G+ G G+PG G G PG G G Sbjct: 377 AGPTGARGPEGAQGPRGEPGTPGSP----GPAGASGNPGTDGIPGAKGSAGAPGIAGAPG 432 Query: 2199 GFGRRGPPGA---------KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISG 2249 G RGPPG KG G PG GF+GEQG +G GPAGP G PG GE+G G Sbjct: 433 FPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRG 492 Query: 2250 PRGSGGAAGA---PGERGRTGPLGRKGEPGEPGPKGGIGNRGP------RGETGDDGRDG 2300 RG G G PGERG G G G+ G GPKG G RGP +G GD GR G Sbjct: 493 ARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPG 552 Query: 2301 V----GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGR---------RGNSG 2347 G+ G G+ G+ G G GP G PGE G G GP+G RG+ +G +G Sbjct: 553 EPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANG 612 Query: 2348 PPGIVGQKGDPGYP---------------GPAGPKGNRGDSIDQCA 2378 PG G+KG PG P GP GP G G+ +Q A Sbjct: 613 EPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 658 Score = 276 bits (706), Expect = 2e-73 Identities = 174/408 (42%), Positives = 203/408 (49%), Gaps = 72/408 (17%) Query: 2038 GQRGDRGPIGSIGPKGI------PGEDGYRGYPGDEGGPGERGPPGV---NGTQGFQGCP 2088 G G+RGP G GPKG PGE G G G G PG+ GP G +G G G P Sbjct: 528 GAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRP 587 Query: 2089 GQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER 2148 G G +G+RG PG G G G +G G+ G+KGLPG+ G +G PG+ G+ G G G Sbjct: 588 GPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPA 647 Query: 2149 GDVGIRGDPGNPGQDSQE-----RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRR 2203 G G RG+ G PG + GP GE G G GVPG G PG G G+ G G R Sbjct: 648 GPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGER 707 Query: 2204 GPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAA------ 2257 G PGA+G +G G PG G G +GA GPAGP G G G QG+ G RG+ G A Sbjct: 708 GSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDR 767 Query: 2258 ---------GAPGE---RGRTGPL---------GRKGEPGEPGPKGGIGNRGPRGETGD- 2295 GAPG+ RG TGP+ G KGE G PGP G G RG GE G+ Sbjct: 768 GDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGET 827 Query: 2296 --------------DGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIR 2340 DG+ G G +G G+KG+ G PG GP G PG G G TGPKG R Sbjct: 828 GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 887 Query: 2341 GRR------------GNSGPPGIVGQKGDPGYPGPA---GPKGNRGDS 2373 G + G GPPG G G PG PGP+ GPKG RGDS Sbjct: 888 GAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDS 935 Score = 271 bits (692), Expect = 1e-71 Identities = 159/351 (45%), Positives = 182/351 (51%), Gaps = 25/351 (7%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G G +G G +GPKG GE G G+ G++G GE GP G QG PG G +G R Sbjct: 438 GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGP------QGAPGPAGEEGKR 491 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGS---SGEKGNPGRRGDKGPRGEKGERGDVGIR 2154 G GE G VG IG G G G++G PG +G KG PG RG G G KG GD G Sbjct: 492 GARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRP 551 Query: 2155 GDPGNPGQD--SQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNG-----GF----GRR 2203 G+PG PG + G G G +GP G PG DG PG PG G G GF G Sbjct: 552 GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 611 Query: 2204 GPPGAKGNKGGPGQPGFEG---EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAP 2260 G PG G KG PG PG G + G GA GP GPAGP G GEQG GP G G G P Sbjct: 612 GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP 671 Query: 2261 GERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPG 2320 G G G G +G PGE G G +G RG RG G+ R G++G +G +G G PG G Sbjct: 672 GPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE--RGSPGAQGLQGPRGLPGTPGTDG 729 Query: 2321 PKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 PKG G G G GP G++G G G GI G KGD G G GP+G G Sbjct: 730 PKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG 780 Score = 270 bits (691), Expect = 1e-71 Identities = 168/401 (41%), Positives = 198/401 (49%), Gaps = 69/401 (17%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G +G+ GP G+ GP+G G G G PG G G G PG +G G +G G G+ G+ Sbjct: 372 GAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAP 431 Query: 2098 GFPGE---------------KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142 GFPG KG+ GE G+ G GE G KG PG +G +G PG G++G R Sbjct: 432 GFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKR 491 Query: 2143 GEKGERGDVGI------RGDPGN---PGQDSQ--------ERGPKGETGDLGPMGVPGRD 2185 G +GE G VG RG PGN PGQD ERGP G G G G PGR Sbjct: 492 GARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRP 551 Query: 2186 GVPGGPGE------------------TGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTR 2227 G PG PG +G G GR GPPG +G +G PG GF G +G Sbjct: 552 GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 611 Query: 2228 GAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNR 2287 G G AG G PG G +G+ G G GAAG PG GP G +GE G PGP G G Sbjct: 612 GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP---AGPAGERGEQGAPGPSGFQGLP 668 Query: 2288 GPRGETGDDGRDG-------VGSEGRRGKKGERGFPGY---PGPKGNPGEPGLNGTTGPK 2337 GP G G+ G+ G G+ G G +GERGFPG PG +G G GL GT G Sbjct: 669 GPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTD 728 Query: 2338 GIRGRRGNSGPPGIVGQKGDPGYPGP------AGPKGNRGD 2372 G +G G +GPPG G G G PG AGPKG+RGD Sbjct: 729 GPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 769 Score = 270 bits (691), Expect = 1e-71 Identities = 155/367 (42%), Positives = 180/367 (49%), Gaps = 32/367 (8%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G G GP G+ G G GE G G GD G PG +GP G G QG G G +G +G++ Sbjct: 831 GPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQ 890 Query: 2098 GFPGEKG---EVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154 G PG G G +G G +G G G PG SG+ G G RGD GP G GE G G Sbjct: 891 GPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPA 950 Query: 2155 GDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGG 2214 G PG G+ + GP G G GP G+ G+ G+ G PG+ G+ G G GP G G +G Sbjct: 951 GPPGEKGEPGDD-GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 1009 Query: 2215 PGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGE 2274 PG G G G G G GPAG PG G G GP G GAAG G+RG TG +G G Sbjct: 1010 PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA 1069 Query: 2275 PG---EPGPKGGIGNRGPRGETGDDGRDG----------------------VGSEGRRGK 2309 PG PGP G G +G RGE G G G G G RG Sbjct: 1070 PGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGL 1129 Query: 2310 KGERGFPGY---PGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGP 2366 KG RGF G PGP G G+ G +G GP G RG G GP G G G PG GP GP Sbjct: 1130 KGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGP 1189 Query: 2367 KGNRGDS 2373 +G G++ Sbjct: 1190 RGRSGET 1196 Score = 266 bits (680), Expect = 2e-70 Identities = 165/408 (40%), Positives = 199/408 (48%), Gaps = 67/408 (16%) Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQ 2085 E+ G+ +G +GDRG +G GP+G PG+DG RG G G PG P G NG +G Sbjct: 754 ERGAAGI----AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPG---PAGANGEKGEV 806 Query: 2086 GCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKG----- 2140 G PG G G+RG PGE+GE G G G G G G PG+ GE+G G++GD G Sbjct: 807 GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 866 Query: 2141 ----------------PRGEKGERGDVGIRGDPG------------NPGQD-----SQER 2167 P+G +G +G G G PG NPG S + Sbjct: 867 GPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKD 926 Query: 2168 GPKGETGDLGPMGVPGRDGV------PGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFE 2221 GPKG GD GP G G G+ PG GE G +G G GPPG +G G G G Sbjct: 927 GPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLP 986 Query: 2222 GEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPK 2281 G++G RG G GP+G PG G G SG RG G G PG G G GR+G PG GP Sbjct: 987 GQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPP 1046 Query: 2282 G---GIGNRGPRGETGDDGRDGV-------GSEGRRGKKGERGFPGYPGPKGNPGEPGLN 2331 G G +G RGETG G G G G GK+G+RG G GP G G G Sbjct: 1047 GRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGAR 1106 Query: 2332 GTTGPKGIRGRRGNSGPPGIVGQKGDPGY------PGPAGPKGNRGDS 2373 G GP+G RG +G +G PG G KG G+ PGP GP G++G S Sbjct: 1107 GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGAS 1154 Score = 265 bits (678), Expect = 4e-70 Identities = 162/396 (40%), Positives = 195/396 (49%), Gaps = 74/396 (18%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G+RG G G GP+G+PG G G +G G GPPG G G QG PG+RG G Sbjct: 705 GERGSPGAQGLQGPRGLPGTPGT---DGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIA 761 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPG------------------------SSGEKGNP 2133 G G++G+VGE G +G G+DG +GL G S+G +G P Sbjct: 762 GPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAP 821 Query: 2134 GRRGDKGPRGE---------------KGERGDVGIRGDPGNPGQDSQERGPKGETGDLGP 2178 G RG+ GP G KGE+G+ G +GD G PG +GP G G GP Sbjct: 822 GERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGP----QGPSGAPGPQGP 877 Query: 2179 MGVPGRDGVPGG---PGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGA------ 2229 GV G G G PG TG G GR GPPG+ GN G PG PG G+ G +GA Sbjct: 878 TGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGP 937 Query: 2230 ---------QGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGE---PGE 2277 QGPAGP G G G+ G SG G G G G+RG G G++GE PG Sbjct: 938 PGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGL 997 Query: 2278 PGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGP 2336 PGP G G +G G +GD G G VG G G GE PG +G+PG G G G Sbjct: 998 PGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGE------PGREGSPGADGPPGRDGA 1051 Query: 2337 KGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 G++G RG +G G G G PG PGPAGP G +GD Sbjct: 1052 AGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGD 1087 Score = 265 bits (678), Expect = 4e-70 Identities = 154/347 (44%), Positives = 180/347 (51%), Gaps = 20/347 (5%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGC----- 2087 P +G +G RG G G G PG G G PG G PG GPPG +G G +G Sbjct: 877 PTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSG 936 Query: 2088 ----PGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRG 2143 G+ G++G G PGEKGE G+ G G +G G +GL G G G PG+RG++G G Sbjct: 937 PPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG 996 Query: 2144 EKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRR 2203 G G+ G +G PG G D GP G G GP G PGR+G PG G G++G G + Sbjct: 997 LPGPSGEPGKQGAPGASG-DRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVK 1055 Query: 2204 GPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGER 2263 G G G G PG PG G+ GPAGP G G GE G GP G G AGA G + Sbjct: 1056 GDRGETGAVGAPGAPG------PPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQ 1109 Query: 2264 GRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV----GSEGRRGKKGERGFPGYP 2319 G GP G KGE GEPG +G G+RG G G G G G+ G G G RG PG Sbjct: 1110 GPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPV 1169 Query: 2320 GPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGP 2366 GP G G G+ G GP G RGR G +GP G G G PG PGP GP Sbjct: 1170 GPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGP 1216 Score = 263 bits (673), Expect = 2e-69 Identities = 156/364 (42%), Positives = 186/364 (51%), Gaps = 29/364 (7%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEG------GPGERGPPGVNGTQGFQGCPGQR 2091 G RG+ G +G IGP G G G RG+PG +G PGERGP G+ G +G G PG+ Sbjct: 492 GARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRP 551 Query: 2092 G------VKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEK 2145 G +G G PG+ G G++G G GEDG G PG G +G PG G GP+G Sbjct: 552 GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 611 Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP 2205 GE G G +G PG PG G GETG GP G G G G G G +G G GP Sbjct: 612 GEPGKAGEKGLPGAPGLRGLP-GKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGP 670 Query: 2206 PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGE---QGISGPRGSGGAAGAPGE 2262 PG G G PG G GE G G GP G G PG G QG+ GPRG G G G Sbjct: 671 PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGP 730 Query: 2263 RGRTGPLGRKGEPGEPGPKGGIGNRG------PRGETGDDGRDGV-GSEGRRGKKGERGF 2315 +G +GP G G G PG +G G RG P+G+ GD G G G+ G+ G +G G Sbjct: 731 KGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGP 790 Query: 2316 PGYPGPKGNPGE------PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGN 2369 G PGP G GE PG G+ G +G G RG +GPPG G G PG G G KG Sbjct: 791 IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGE 850 Query: 2370 RGDS 2373 +G++ Sbjct: 851 QGEA 854 Score = 261 bits (667), Expect = 8e-69 Identities = 156/361 (43%), Positives = 180/361 (49%), Gaps = 27/361 (7%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDG---------YRGYPGDEGGPGERGPPGVNGTQGFQGCP 2088 G+ G GP GS G +G PGE G + G PG +G PG +G G G +G G P Sbjct: 804 GEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAP 863 Query: 2089 GQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGE---K 2145 G +G G+ G G G G G G G G G PG++G G PG G+ GP G Sbjct: 864 GPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPS 923 Query: 2146 GERGDVGIRGDPGNPGQDSQE--RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRR 2203 G+ G G RGD G PG+ + +GP G G+ G G G G G PG G G G Sbjct: 924 GKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIV 983 Query: 2204 GPPGAKGNKGGPGQPGFEGEQGTRGA------QGPAGPAGPPGLIGEQGISGPRGSGGAA 2257 G PG +G +G PG PG GE G +GA +GP GP GPPGL G G G GS GA Sbjct: 984 GLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGAD 1043 Query: 2258 GAPGERGRTGPLGRKGE------PGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKK 2310 G PG G G G +GE PG PGP G G GP G+ GD G G G G G Sbjct: 1044 GPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPA 1103 Query: 2311 GERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNR 2370 G RG G GP+G+ GE G G G KG RG G G PG G GD G GPAGP G R Sbjct: 1104 GARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPR 1163 Query: 2371 G 2371 G Sbjct: 1164 G 1164 Score = 252 bits (644), Expect = 4e-66 Identities = 157/364 (43%), Positives = 178/364 (48%), Gaps = 39/364 (10%) Query: 2038 GQRGDRGPIGSI-GPKGIPGEDG---YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGV 2093 GQ+G+ G I I GPKG PG G +G GD G GE+G PG G G G PG G Sbjct: 104 GQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGP 163 Query: 2094 KGSRGFPGEKGEVGEIGLD---GLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD 2150 G G PG G G G D + G L G G G RG GP G G +G Sbjct: 164 PGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGF 223 Query: 2151 VGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKG 2210 G G+PG P G +G +GP G PG G PG GE GK G G RGPPG +G Sbjct: 224 QGNPGEPGEP----------GVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQG 273 Query: 2211 NKGGPGQPGFEGEQGTR---GAQGPAGPAGPPGLIGEQGISGPRGSG---GAAGAPGERG 2264 +G PG PG G +G R G G G AG PG+ GE G G GS G G PGERG Sbjct: 274 ARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERG 333 Query: 2265 RTGP---LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV----------GSEGRRGKKG 2311 RTGP G +G G+PGP G G GP G G G G G EG +G +G Sbjct: 334 RTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRG 393 Query: 2312 ERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDP---GYPGPAGPKG 2368 E G PG PGP G G PG +G G KG G G +G PG G +G P G GP GPKG Sbjct: 394 EPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKG 453 Query: 2369 NRGD 2372 G+ Sbjct: 454 QTGE 457 Score = 233 bits (593), Expect = 3e-60 Identities = 140/322 (43%), Positives = 159/322 (49%), Gaps = 12/322 (3%) Query: 2053 GIPGEDGYRGYPGD-EGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGL 2111 G PG G +G PGD + G +GPPG G G QG G RG KG +G PG +G GE G Sbjct: 98 GQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT 157 Query: 2112 DGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKG 2171 G G G G PG G GN + G EK +G+ P P GP+G Sbjct: 158 PGNPGPPGPPGPPGPPGLGGNFAAQM-AGGFDEKAGGAQLGVMQGPMGP------MGPRG 210 Query: 2172 ETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQG 2231 G G G G G PG PGE G +G G RGPPG G G G+ G G+ G RG G Sbjct: 211 PPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPG 270 Query: 2232 PAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRG 2291 P G G PG G G+ G RG G GA GE G G KGE G PG G G GPRG Sbjct: 271 PQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGV---KGESGSPGENGSPGPMGPRG 327 Query: 2292 ETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPG 2350 G+ GR G G+ G RG G+ G G PGP G G PG G G KG G G GP G Sbjct: 328 LPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEG 387 Query: 2351 IVGQKGDPGYPGPAGPKGNRGD 2372 G +G+PG PG GP G G+ Sbjct: 388 AQGPRGEPGTPGSPGPAGASGN 409 Score = 171 bits (433), Expect = 1e-41 Identities = 103/247 (41%), Positives = 121/247 (48%), Gaps = 18/247 (7%) Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGF- 2084 ++ G+P GQRG+RG G GP G PG+ G G GD G PG GPPG+ G G Sbjct: 979 QRGIVGLP----GQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEP 1034 Query: 2085 --QGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142 +G PG G G G G KG+ GE G G G G G PG +G G G RG+ G + Sbjct: 1035 GREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQ 1094 Query: 2143 GEKGERGDVGIRG--DPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPG---ETGKN 2197 G G G G RG P P D E G GE G G G G G+PG PG + G + Sbjct: 1095 GPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGAS 1154 Query: 2198 GGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAA 2257 GP G G +G PG G G+ G G GP GP GP G GE G +GP G+ G Sbjct: 1155 ------GPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP 1208 Query: 2258 GAPGERG 2264 G PG G Sbjct: 1209 GPPGPPG 1215 Score = 159 bits (403), Expect = 3e-38 Identities = 103/280 (36%), Positives = 119/280 (42%), Gaps = 77/280 (27%) Query: 2169 PKGETGDLGPMGVPGRDGVPGGPGETGKNGGF----GRRGPPGA---------------K 2209 P GE + P + G PG G+ G+ G G +GPPG K Sbjct: 81 PFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDK 140 Query: 2210 GNKGGPGQPGFEGEQGTRGAQGPAGPAGPPG---------------------------LI 2242 G KG PG G +GE GT G GP GP GPPG + Sbjct: 141 GEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQ 200 Query: 2243 GEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-- 2300 G G GPRG G AGAPG +G G G GEPG GP G G GP G+ GDDG G Sbjct: 201 GPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKP 260 Query: 2301 --VGSEGRRGKKGERGFPGYP---------------------------GPKGNPGEPGLN 2331 G G G +G RGFPG P G G+PGE G Sbjct: 261 GKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSP 320 Query: 2332 GTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 G GP+G+ G RG +GP G G +G+ G PGPAGP G G Sbjct: 321 GPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVG 360 Score = 80.5 bits (197), Expect = 2e-14 Identities = 54/140 (38%), Positives = 65/140 (46%), Gaps = 27/140 (19%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G RGD+G G G +G+ G+RG+ G +G PG GP G QG G G G R Sbjct: 1113 GPRGDKGEAGEPGERGL---KGHRGFTGLQGLPGPPGP------SGDQGASGPAGPSGPR 1163 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157 G PG G G+DG G+PG G G GR G+ GP G G G G G P Sbjct: 1164 GPPGPVGP---------SGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPP 1214 Query: 2158 GNPGQD--------SQERGP 2169 G PG D +E+GP Sbjct: 1215 G-PGIDMSAFAGLGPREKGP 1233 Score = 69.7 bits (169), Expect = 4e-11 Identities = 44/119 (36%), Positives = 53/119 (44%), Gaps = 36/119 (30%) Query: 2264 GRTGPLGRKGEPGE----PGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYP 2319 G+ GP G+KGEPG+ GPKG G +GP G +G RG +G++G G P Sbjct: 98 GQPGPKGQKGEPGDIKDIVGPKGPPGPQGP-----------AGEQGPRGDRGDKGEKGAP 146 Query: 2320 GPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCA 2378 GP RG G PG G G PG PGP GP G G+ Q A Sbjct: 147 GP---------------------RGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMA 184 Score = 33.5 bits (75), Expect = 3.4 Identities = 18/41 (43%), Positives = 21/41 (51%), Gaps = 10/41 (24%) Query: 2346 SGPPGIVGQKGDP----------GYPGPAGPKGNRGDSIDQ 2376 SG PG GQKG+P G PGP GP G +G D+ Sbjct: 97 SGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDR 137 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 293 bits (749), Expect = 2e-78 Identities = 164/373 (43%), Positives = 194/373 (52%), Gaps = 43/373 (11%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096 +G G GP G G +G PG G++G PG G PGE G PG G G G PG G +G Sbjct: 572 AGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGE 631 Query: 2097 RGFPGEKGEVGEIGLDG------LDGEDGDKGLPGSSGE---------KGNPGRRGDKGP 2141 RGFPGE+G G GL G G DG KG G +G +G PG RG G Sbjct: 632 RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 691 Query: 2142 RGEKGERGDVGIRGDPGNPGQDSQE--------------RGPKGETGDLGPMGVPGRDGV 2187 G KG+RGDVG +G G PG+D G KGE G GP G G G Sbjct: 692 AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA 751 Query: 2188 PGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGI 2247 PG GETG G G GPPGA G G G+ G G++G GA GP GP+G PG G G+ Sbjct: 752 PGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGV 811 Query: 2248 SGPRGSGGAAGAPGERG------RTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV 2301 +GP+G+ GA G PG G R GP G G PG PGP G G GP+G GD Sbjct: 812 TGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDS----- 866 Query: 2302 GSEGRRGKKGERGFPGYPGPKGNPGE---PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDP 2358 G GR G+ G +G G PG KG PG+ G G GP+G+ G+RG G PG G++G P Sbjct: 867 GPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFP 926 Query: 2359 GYPGPAGPKGNRG 2371 G PGP+G G +G Sbjct: 927 GLPGPSGEPGKQG 939 Score = 290 bits (742), Expect = 2e-77 Identities = 166/361 (45%), Positives = 189/361 (52%), Gaps = 38/361 (10%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G+ G GP+G GP G PG+ G G G G GERGPPG G +GF G PG GVKG R Sbjct: 162 GEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHR 221 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157 G+PG G GE G G+ GE G S GE G+PG G +G GE+G G G G Sbjct: 222 GYPGLDGAKGEAGAPGVKGESG------SPGENGSPGPMGPRGLPGERGRTGPAGAAGAR 275 Query: 2158 GNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQ 2217 GN GQ GP G G +GP G PG G PG GE G G RGP GA+G +G PG Sbjct: 276 GNDGQP----GPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGA---RGPEGAQGPRGEPGT 328 Query: 2218 PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGE 2277 PG G G G G G G G G GI+G G G G PG +G TGPLG KG+ GE Sbjct: 329 PGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGE 388 Query: 2278 PGPKGGIGNRGPRGETGDDGRDG----VGSEGRRGKKGE------------------RGF 2315 PG G G +GP+GE G G G G EG+RG +GE RGF Sbjct: 389 PGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGF 448 Query: 2316 P---GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 P G GPKG PGE G +G GPKG G G G PG+ G +G G PG AGP+G G Sbjct: 449 PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGP 508 Query: 2373 S 2373 S Sbjct: 509 S 509 Score = 283 bits (723), Expect = 2e-75 Identities = 173/406 (42%), Positives = 202/406 (49%), Gaps = 74/406 (18%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGG------------------PGERGPPGV 2078 +G+ GD GP G +GP G PGEDG G PG +G PG+ G G+ Sbjct: 494 TGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGL 553 Query: 2079 NGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGD 2138 G G +G PG+ G G+ G PG G GE G G G G +GLPG G G G+ GD Sbjct: 554 PGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGD 613 Query: 2139 K------------GPRGEK---GERGDVGI------RGDPGNPGQDSQERGPKGETGDLG 2177 + GPRGE+ GERG G RG PG PG D GPKG +G G Sbjct: 614 QGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTD----GPKGASGPAG 669 Query: 2178 PMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAG 2237 P G G G+ G PGE G G G +G G G KG G PG +G +G G GP GPAG Sbjct: 670 PPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAG 729 Query: 2238 PPGLIGEQGISGPRGSGGAAGAPGERGRTGP---------------LGRKGEPGEPGPKG 2282 G GE G GP GS GA GAPGERG TGP G KGE GE G KG Sbjct: 730 ANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKG 789 Query: 2283 GIGNRGPRGETGDDGRDG-------VGSEGRRGKKGERGFPGY------PGPKGNPGEPG 2329 G GP+G +G G G G+ G +G G GFPG PG GNPG PG Sbjct: 790 DAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG 849 Query: 2330 LNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSID 2375 G +G G +G RG+SGPP G+ G+PG GPAGP G +G+ D Sbjct: 850 PPGPSGKDGPKGARGDSGPP---GRAGEPGLQGPAGPPGEKGEPGD 892 Score = 279 bits (713), Expect = 4e-74 Identities = 158/349 (45%), Positives = 180/349 (51%), Gaps = 12/349 (3%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096 +G G RG G GP G PG G G PG G PG +G G G +G +G G RG G+ Sbjct: 269 AGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGT 328 Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGD 2156 G PG G G G DG+ G G G PG +G G PG RG GP+G G G G G+ Sbjct: 329 PGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGE 388 Query: 2157 PGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPG---AKGNKG 2213 PG G E+GPKGE G GP G PG G G G G+ GG G GPPG A GN+G Sbjct: 389 PGIAGFKG-EQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRG 447 Query: 2214 GPGQPGFEGEQGTRGAQGPAGPAGP------PGLIGEQGISGPRGSGGAAGAPGERGRTG 2267 PGQ G G +G G +GP+G AGP PG GE G+ G RG G G G +G+ G Sbjct: 448 FPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVG 507 Query: 2268 PLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGE 2327 P G GE G PGP G G RG G G G G + G GK GE+G PG PG +G PG+ Sbjct: 508 PSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKG--ANGEPGKAGEKGLPGAPGLRGLPGK 565 Query: 2328 PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQ 2376 G G GP G G G G G G G G PGP GP G G DQ Sbjct: 566 DGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQ 614 Score = 276 bits (706), Expect = 2e-73 Identities = 171/406 (42%), Positives = 200/406 (49%), Gaps = 63/406 (15%) Query: 2031 GVPCKCSGQRGDRGPIGSIG---PKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGC 2087 G P K +G+RG GP G+ G G+PG G+RGYPG +G GE G PGV G G G Sbjct: 189 GKPGK-AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGE 247 Query: 2088 PGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGE---------KGNPGRRGD 2138 G G G RG PGE+G G G G G DG G G G G PG +G+ Sbjct: 248 NGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGE 307 Query: 2139 KGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNG 2198 GP G +G G G RG+PG PG GP G +G+ G G+PG G G PG G G Sbjct: 308 AGPTGARGPEGAQGPRGEPGTPGSP----GPAGASGNPGTDGIPGAKGSAGAPGIAGAPG 363 Query: 2199 GFGRRGPPGA---------KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISG 2249 G RGPPG KG G PG GF+GEQG +G GPAGP G PG GE+G G Sbjct: 364 FPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRG 423 Query: 2250 PRGSGGAAGA---PGERGRTGPLGRKGEPGEPGPKGGIGNRGP------RGETGDDGRDG 2300 RG G G PGERG G G G+ G GPKG G RGP +G GD GR G Sbjct: 424 ARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPG 483 Query: 2301 V----GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGR---------RGNSG 2347 G+ G G+ G+ G G GP G PGE G G GP+G RG+ +G +G Sbjct: 484 EPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANG 543 Query: 2348 PPGIVGQKGDPGYP---------------GPAGPKGNRGDSIDQCA 2378 PG G+KG PG P GP GP G G+ +Q A Sbjct: 544 EPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 589 Score = 276 bits (706), Expect = 2e-73 Identities = 174/408 (42%), Positives = 203/408 (49%), Gaps = 72/408 (17%) Query: 2038 GQRGDRGPIGSIGPKGI------PGEDGYRGYPGDEGGPGERGPPGV---NGTQGFQGCP 2088 G G+RGP G GPKG PGE G G G G PG+ GP G +G G G P Sbjct: 459 GAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRP 518 Query: 2089 GQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER 2148 G G +G+RG PG G G G +G G+ G+KGLPG+ G +G PG+ G+ G G G Sbjct: 519 GPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPA 578 Query: 2149 GDVGIRGDPGNPGQDSQE-----RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRR 2203 G G RG+ G PG + GP GE G G GVPG G PG G G+ G G R Sbjct: 579 GPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGER 638 Query: 2204 GPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAA------ 2257 G PGA+G +G G PG G G +GA GPAGP G G G QG+ G RG+ G A Sbjct: 639 GSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDR 698 Query: 2258 ---------GAPGE---RGRTGPL---------GRKGEPGEPGPKGGIGNRGPRGETGD- 2295 GAPG+ RG TGP+ G KGE G PGP G G RG GE G+ Sbjct: 699 GDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGET 758 Query: 2296 --------------DGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIR 2340 DG+ G G +G G+KG+ G PG GP G PG G G TGPKG R Sbjct: 759 GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 818 Query: 2341 GRR------------GNSGPPGIVGQKGDPGYPGPA---GPKGNRGDS 2373 G + G GPPG G G PG PGP+ GPKG RGDS Sbjct: 819 GAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDS 866 Score = 271 bits (692), Expect = 1e-71 Identities = 159/351 (45%), Positives = 182/351 (51%), Gaps = 25/351 (7%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G G +G G +GPKG GE G G+ G++G GE GP G QG PG G +G R Sbjct: 369 GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGP------QGAPGPAGEEGKR 422 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGS---SGEKGNPGRRGDKGPRGEKGERGDVGIR 2154 G GE G VG IG G G G++G PG +G KG PG RG G G KG GD G Sbjct: 423 GARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRP 482 Query: 2155 GDPGNPGQD--SQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNG-----GF----GRR 2203 G+PG PG + G G G +GP G PG DG PG PG G G GF G Sbjct: 483 GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 542 Query: 2204 GPPGAKGNKGGPGQPGFEG---EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAP 2260 G PG G KG PG PG G + G GA GP GPAGP G GEQG GP G G G P Sbjct: 543 GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP 602 Query: 2261 GERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPG 2320 G G G G +G PGE G G +G RG RG G+ R G++G +G +G G PG G Sbjct: 603 GPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE--RGSPGAQGLQGPRGLPGTPGTDG 660 Query: 2321 PKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 PKG G G G GP G++G G G GI G KGD G G GP+G G Sbjct: 661 PKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG 711 Score = 270 bits (691), Expect = 1e-71 Identities = 168/401 (41%), Positives = 198/401 (49%), Gaps = 69/401 (17%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G +G+ GP G+ GP+G G G G PG G G G PG +G G +G G G+ G+ Sbjct: 303 GAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAP 362 Query: 2098 GFPGE---------------KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142 GFPG KG+ GE G+ G GE G KG PG +G +G PG G++G R Sbjct: 363 GFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKR 422 Query: 2143 GEKGERGDVGI------RGDPGN---PGQDSQ--------ERGPKGETGDLGPMGVPGRD 2185 G +GE G VG RG PGN PGQD ERGP G G G G PGR Sbjct: 423 GARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRP 482 Query: 2186 GVPGGPGE------------------TGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTR 2227 G PG PG +G G GR GPPG +G +G PG GF G +G Sbjct: 483 GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 542 Query: 2228 GAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNR 2287 G G AG G PG G +G+ G G GAAG PG GP G +GE G PGP G G Sbjct: 543 GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP---AGPAGERGEQGAPGPSGFQGLP 599 Query: 2288 GPRGETGDDGRDG-------VGSEGRRGKKGERGFPGY---PGPKGNPGEPGLNGTTGPK 2337 GP G G+ G+ G G+ G G +GERGFPG PG +G G GL GT G Sbjct: 600 GPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTD 659 Query: 2338 GIRGRRGNSGPPGIVGQKGDPGYPGP------AGPKGNRGD 2372 G +G G +GPPG G G G PG AGPKG+RGD Sbjct: 660 GPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 700 Score = 270 bits (691), Expect = 1e-71 Identities = 155/367 (42%), Positives = 180/367 (49%), Gaps = 32/367 (8%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G G GP G+ G G GE G G GD G PG +GP G G QG G G +G +G++ Sbjct: 762 GPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQ 821 Query: 2098 GFPGEKG---EVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154 G PG G G +G G +G G G PG SG+ G G RGD GP G GE G G Sbjct: 822 GPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPA 881 Query: 2155 GDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGG 2214 G PG G+ + GP G G GP G+ G+ G+ G PG+ G+ G G GP G G +G Sbjct: 882 GPPGEKGEPGDD-GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 940 Query: 2215 PGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGE 2274 PG G G G G G GPAG PG G G GP G GAAG G+RG TG +G G Sbjct: 941 PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA 1000 Query: 2275 PG---EPGPKGGIGNRGPRGETGDDGRDG----------------------VGSEGRRGK 2309 PG PGP G G +G RGE G G G G G RG Sbjct: 1001 PGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGL 1060 Query: 2310 KGERGFPGY---PGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGP 2366 KG RGF G PGP G G+ G +G GP G RG G GP G G G PG GP GP Sbjct: 1061 KGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGP 1120 Query: 2367 KGNRGDS 2373 +G G++ Sbjct: 1121 RGRSGET 1127 Score = 266 bits (680), Expect = 2e-70 Identities = 165/408 (40%), Positives = 199/408 (48%), Gaps = 67/408 (16%) Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQ 2085 E+ G+ +G +GDRG +G GP+G PG+DG RG G G PG P G NG +G Sbjct: 685 ERGAAGI----AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPG---PAGANGEKGEV 737 Query: 2086 GCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKG----- 2140 G PG G G+RG PGE+GE G G G G G G PG+ GE+G G++GD G Sbjct: 738 GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 797 Query: 2141 ----------------PRGEKGERGDVGIRGDPG------------NPGQD-----SQER 2167 P+G +G +G G G PG NPG S + Sbjct: 798 GPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKD 857 Query: 2168 GPKGETGDLGPMGVPGRDGV------PGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFE 2221 GPKG GD GP G G G+ PG GE G +G G GPPG +G G G G Sbjct: 858 GPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLP 917 Query: 2222 GEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPK 2281 G++G RG G GP+G PG G G SG RG G G PG G G GR+G PG GP Sbjct: 918 GQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPP 977 Query: 2282 G---GIGNRGPRGETGDDGRDGV-------GSEGRRGKKGERGFPGYPGPKGNPGEPGLN 2331 G G +G RGETG G G G G GK+G+RG G GP G G G Sbjct: 978 GRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGAR 1037 Query: 2332 GTTGPKGIRGRRGNSGPPGIVGQKGDPGY------PGPAGPKGNRGDS 2373 G GP+G RG +G +G PG G KG G+ PGP GP G++G S Sbjct: 1038 GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGAS 1085 Score = 265 bits (678), Expect = 4e-70 Identities = 162/396 (40%), Positives = 195/396 (49%), Gaps = 74/396 (18%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G+RG G G GP+G+PG G G +G G GPPG G G QG PG+RG G Sbjct: 636 GERGSPGAQGLQGPRGLPGTPGT---DGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIA 692 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPG------------------------SSGEKGNP 2133 G G++G+VGE G +G G+DG +GL G S+G +G P Sbjct: 693 GPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAP 752 Query: 2134 GRRGDKGPRGE---------------KGERGDVGIRGDPGNPGQDSQERGPKGETGDLGP 2178 G RG+ GP G KGE+G+ G +GD G PG +GP G G GP Sbjct: 753 GERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGP----QGPSGAPGPQGP 808 Query: 2179 MGVPGRDGVPGG---PGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGA------ 2229 GV G G G PG TG G GR GPPG+ GN G PG PG G+ G +GA Sbjct: 809 TGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGP 868 Query: 2230 ---------QGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGE---PGE 2277 QGPAGP G G G+ G SG G G G G+RG G G++GE PG Sbjct: 869 PGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGL 928 Query: 2278 PGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGP 2336 PGP G G +G G +GD G G VG G G GE PG +G+PG G G G Sbjct: 929 PGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGE------PGREGSPGADGPPGRDGA 982 Query: 2337 KGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 G++G RG +G G G G PG PGPAGP G +GD Sbjct: 983 AGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGD 1018 Score = 265 bits (678), Expect = 4e-70 Identities = 154/347 (44%), Positives = 180/347 (51%), Gaps = 20/347 (5%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGC----- 2087 P +G +G RG G G G PG G G PG G PG GPPG +G G +G Sbjct: 808 PTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSG 867 Query: 2088 ----PGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRG 2143 G+ G++G G PGEKGE G+ G G +G G +GL G G G PG+RG++G G Sbjct: 868 PPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG 927 Query: 2144 EKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRR 2203 G G+ G +G PG G D GP G G GP G PGR+G PG G G++G G + Sbjct: 928 LPGPSGEPGKQGAPGASG-DRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVK 986 Query: 2204 GPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGER 2263 G G G G PG PG G+ GPAGP G G GE G GP G G AGA G + Sbjct: 987 GDRGETGAVGAPGAPG------PPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQ 1040 Query: 2264 GRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV----GSEGRRGKKGERGFPGYP 2319 G GP G KGE GEPG +G G+RG G G G G G+ G G G RG PG Sbjct: 1041 GPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPV 1100 Query: 2320 GPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGP 2366 GP G G G+ G GP G RGR G +GP G G G PG PGP GP Sbjct: 1101 GPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGP 1147 Score = 263 bits (673), Expect = 2e-69 Identities = 156/364 (42%), Positives = 186/364 (51%), Gaps = 29/364 (7%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEG------GPGERGPPGVNGTQGFQGCPGQR 2091 G RG+ G +G IGP G G G RG+PG +G PGERGP G+ G +G G PG+ Sbjct: 423 GARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRP 482 Query: 2092 G------VKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEK 2145 G +G G PG+ G G++G G GEDG G PG G +G PG G GP+G Sbjct: 483 GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 542 Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP 2205 GE G G +G PG PG G GETG GP G G G G G G +G G GP Sbjct: 543 GEPGKAGEKGLPGAPGLRGLP-GKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGP 601 Query: 2206 PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGE---QGISGPRGSGGAAGAPGE 2262 PG G G PG G GE G G GP G G PG G QG+ GPRG G G G Sbjct: 602 PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGP 661 Query: 2263 RGRTGPLGRKGEPGEPGPKGGIGNRG------PRGETGDDGRDGV-GSEGRRGKKGERGF 2315 +G +GP G G G PG +G G RG P+G+ GD G G G+ G+ G +G G Sbjct: 662 KGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGP 721 Query: 2316 PGYPGPKGNPGE------PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGN 2369 G PGP G GE PG G+ G +G G RG +GPPG G G PG G G KG Sbjct: 722 IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGE 781 Query: 2370 RGDS 2373 +G++ Sbjct: 782 QGEA 785 Score = 261 bits (667), Expect = 8e-69 Identities = 156/361 (43%), Positives = 180/361 (49%), Gaps = 27/361 (7%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDG---------YRGYPGDEGGPGERGPPGVNGTQGFQGCP 2088 G+ G GP GS G +G PGE G + G PG +G PG +G G G +G G P Sbjct: 735 GEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAP 794 Query: 2089 GQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGE---K 2145 G +G G+ G G G G G G G G G PG++G G PG G+ GP G Sbjct: 795 GPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPS 854 Query: 2146 GERGDVGIRGDPGNPGQDSQE--RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRR 2203 G+ G G RGD G PG+ + +GP G G+ G G G G G PG G G G Sbjct: 855 GKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIV 914 Query: 2204 GPPGAKGNKGGPGQPGFEGEQGTRGA------QGPAGPAGPPGLIGEQGISGPRGSGGAA 2257 G PG +G +G PG PG GE G +GA +GP GP GPPGL G G G GS GA Sbjct: 915 GLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGAD 974 Query: 2258 GAPGERGRTGPLGRKGE------PGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKK 2310 G PG G G G +GE PG PGP G G GP G+ GD G G G G G Sbjct: 975 GPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPA 1034 Query: 2311 GERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNR 2370 G RG G GP+G+ GE G G G KG RG G G PG G GD G GPAGP G R Sbjct: 1035 GARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPR 1094 Query: 2371 G 2371 G Sbjct: 1095 G 1095 Score = 252 bits (644), Expect = 4e-66 Identities = 157/364 (43%), Positives = 178/364 (48%), Gaps = 39/364 (10%) Query: 2038 GQRGDRGPIGSI-GPKGIPGEDG---YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGV 2093 GQ+G+ G I I GPKG PG G +G GD G GE+G PG G G G PG G Sbjct: 35 GQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGP 94 Query: 2094 KGSRGFPGEKGEVGEIGLD---GLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD 2150 G G PG G G G D + G L G G G RG GP G G +G Sbjct: 95 PGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGF 154 Query: 2151 VGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKG 2210 G G+PG P G +G +GP G PG G PG GE GK G G RGPPG +G Sbjct: 155 QGNPGEPGEP----------GVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQG 204 Query: 2211 NKGGPGQPGFEGEQGTR---GAQGPAGPAGPPGLIGEQGISGPRGSG---GAAGAPGERG 2264 +G PG PG G +G R G G G AG PG+ GE G G GS G G PGERG Sbjct: 205 ARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERG 264 Query: 2265 RTGP---LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV----------GSEGRRGKKG 2311 RTGP G +G G+PGP G G GP G G G G G EG +G +G Sbjct: 265 RTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRG 324 Query: 2312 ERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDP---GYPGPAGPKG 2368 E G PG PGP G G PG +G G KG G G +G PG G +G P G GP GPKG Sbjct: 325 EPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKG 384 Query: 2369 NRGD 2372 G+ Sbjct: 385 QTGE 388 Score = 231 bits (590), Expect = 7e-60 Identities = 139/320 (43%), Positives = 158/320 (49%), Gaps = 12/320 (3%) Query: 2055 PGEDGYRGYPGD-EGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDG 2113 PG G +G PGD + G +GPPG G G QG G RG KG +G PG +G GE G G Sbjct: 31 PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPG 90 Query: 2114 LDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGET 2173 G G G PG G GN + G EK +G+ P P GP+G Sbjct: 91 NPGPPGPPGPPGPPGLGGNFAAQM-AGGFDEKAGGAQLGVMQGPMGP------MGPRGPP 143 Query: 2174 GDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPA 2233 G G G G G PG PGE G +G G RGPPG G G G+ G G+ G RG GP Sbjct: 144 GPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 203 Query: 2234 GPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGET 2293 G G PG G G+ G RG G GA GE G G KGE G PG G G GPRG Sbjct: 204 GARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGV---KGESGSPGENGSPGPMGPRGLP 260 Query: 2294 GDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIV 2352 G+ GR G G+ G RG G+ G G PGP G G PG G G KG G G GP G Sbjct: 261 GERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQ 320 Query: 2353 GQKGDPGYPGPAGPKGNRGD 2372 G +G+PG PG GP G G+ Sbjct: 321 GPRGEPGTPGSPGPAGASGN 340 Score = 173 bits (439), Expect = 2e-42 Identities = 106/273 (38%), Positives = 122/273 (44%), Gaps = 68/273 (24%) Query: 2161 GQDSQERGPKGETGD-------LGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKG 2213 GQD ++ GPKG+ G+ +GP G PG G G G G G G +G PG +G G Sbjct: 25 GQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDG 84 Query: 2214 GPGQPGFEGEQGTRGAQGPAGPAGPPGL------------------------IGEQGISG 2249 PG P G G GP GP GPPGL G G G Sbjct: 85 EPGTP------GNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMG 138 Query: 2250 PRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG----VGSEG 2305 PRG G AGAPG +G G G GEPG GP G G GP G+ GDDG G G G Sbjct: 139 PRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERG 198 Query: 2306 RRGKKGERGFPGYP---------------------------GPKGNPGEPGLNGTTGPKG 2338 G +G RGFPG P G G+PGE G G GP+G Sbjct: 199 PPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRG 258 Query: 2339 IRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 + G RG +GP G G +G+ G PGPAGP G G Sbjct: 259 LPGERGRTGPAGAAGARGNDGQPGPAGPPGPVG 291 Score = 171 bits (433), Expect = 1e-41 Identities = 103/247 (41%), Positives = 121/247 (48%), Gaps = 18/247 (7%) Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGF- 2084 ++ G+P GQRG+RG G GP G PG+ G G GD G PG GPPG+ G G Sbjct: 910 QRGIVGLP----GQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEP 965 Query: 2085 --QGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142 +G PG G G G G KG+ GE G G G G G PG +G G G RG+ G + Sbjct: 966 GREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQ 1025 Query: 2143 GEKGERGDVGIRG--DPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPG---ETGKN 2197 G G G G RG P P D E G GE G G G G G+PG PG + G + Sbjct: 1026 GPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGAS 1085 Query: 2198 GGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAA 2257 GP G G +G PG G G+ G G GP GP GP G GE G +GP G+ G Sbjct: 1086 ------GPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP 1139 Query: 2258 GAPGERG 2264 G PG G Sbjct: 1140 GPPGPPG 1146 Score = 80.5 bits (197), Expect = 2e-14 Identities = 54/140 (38%), Positives = 65/140 (46%), Gaps = 27/140 (19%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G RGD+G G G +G+ G+RG+ G +G PG GP G QG G G G R Sbjct: 1044 GPRGDKGEAGEPGERGL---KGHRGFTGLQGLPGPPGP------SGDQGASGPAGPSGPR 1094 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157 G PG G G+DG G+PG G G GR G+ GP G G G G G P Sbjct: 1095 GPPGPVGP---------SGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPP 1145 Query: 2158 GNPGQD--------SQERGP 2169 G PG D +E+GP Sbjct: 1146 G-PGIDMSAFAGLGPREKGP 1164 Score = 67.4 bits (163), Expect = 2e-10 Identities = 43/116 (37%), Positives = 51/116 (43%), Gaps = 36/116 (31%) Query: 2267 GPLGRKGEPGE----PGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPK 2322 GP G+KGEPG+ GPKG G +GP G +G RG +G++G G PGP Sbjct: 32 GPKGQKGEPGDIKDIVGPKGPPGPQGP-----------AGEQGPRGDRGDKGEKGAPGP- 79 Query: 2323 GNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCA 2378 RG G PG G G PG PGP GP G G+ Q A Sbjct: 80 --------------------RGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMA 115 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 289 bits (739), Expect = 3e-77 Identities = 170/401 (42%), Positives = 205/401 (51%), Gaps = 71/401 (17%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERG---------------PPGVNGTQ 2082 G G++GP G G G+PG DG G+PG EG GE+G P GV G Sbjct: 721 GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGAD 780 Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142 G +G G +G KG GFPG KG++G G G G+ G +G G G KG G GD GP Sbjct: 781 GVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPS 840 Query: 2143 GEKGERGDVGIRGDPGNPGQDSQERGPKGET---------GDLGPMGVPGRDGVPGGPGE 2193 G+ GE+G +G+ G PG PG+ +GPKG T G+ G GV G+ G G G Sbjct: 841 GQAGEKGKLGVPGLPGYPGR----QGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP 896 Query: 2194 TGKNGGFGRRGP---PGAKGNKGGPGQPGFEGEQGTRGAQGPA---GPAGPPGLIGE--- 2244 TG G G RGP PG KG GG G PG GE+G +G QGP GP GPPG G+ Sbjct: 897 TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL 956 Query: 2245 ------------QGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGP------------ 2280 QG +GP G GG G G G TGP+G +G PG PGP Sbjct: 957 PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 1016 Query: 2281 KGGIGNRGPRGETGDDGRDGV----------GSEGRRGKKGERGFPGYPGPKGNPGEPGL 2330 +G G+ GP+G +G DG G+ G++G G KG G G PGP G+PGE G Sbjct: 1017 EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGS 1076 Query: 2331 NGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 GT GP G+ GR G GPPG G+KG PG GP GP G G Sbjct: 1077 AGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1117 Score = 286 bits (731), Expect = 3e-76 Identities = 164/353 (46%), Positives = 194/353 (54%), Gaps = 20/353 (5%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDG---YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094 G+ G GP G +GP+G GE G RG+PG G PGE+G PG G +G +G PG +G+ Sbjct: 970 GKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGIS 1029 Query: 2095 GS------RGFPGEKGEVGEIGLDGLDGEDGDKGLPG---SSGEKGNPGRRGDKGPRGEK 2145 G RGFPGE+G G G GL G +G +G PG S GE+G+ G G G G Sbjct: 1030 GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRP 1089 Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP 2205 G +G G G+ G PG+ + GP G G GP+G+PG G G PGE G G G G Sbjct: 1090 GPQGPPGPAGEKGAPGEKGPQ-GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ 1148 Query: 2206 PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE--- 2262 G+KG+KG G PG G QG GA G AG G PG G+QG+ G +G GA G PG Sbjct: 1149 KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP 1208 Query: 2263 ---RGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGY 2318 +G GP G KGE G+ GP G G GPRG G +G DG G G G G G G Sbjct: 1209 IGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1268 Query: 2319 PGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 PG GNPG PG G GPKG RG +G +GPPG G G G PG GPKGN G Sbjct: 1269 PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPG 1321 Score = 284 bits (726), Expect = 1e-75 Identities = 163/384 (42%), Positives = 195/384 (50%), Gaps = 52/384 (13%) Query: 2038 GQRGDRGPIGSIG---PKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQG---FQGCPGQR 2091 G G+ GPIG G P G PGE G G G EG G+ GP G++G G +G PG+R Sbjct: 985 GPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGER 1044 Query: 2092 GVKGSR------------------GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNP 2133 G+ G++ G PGE+G G G GL G G +G PG +GEKG P Sbjct: 1045 GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1104 Query: 2134 GRRGDKGPRGEKGERGDVGI---------------RGDPGNPGQ-----DSQERGPKGET 2173 G +G +GP G G +G VG+ +G+ G PGQ D E GP G Sbjct: 1105 GEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP 1164 Query: 2174 GDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFE---GEQGTRGAQ 2230 G GP+G PG G G PG G+ G FG++G GA+G G PG G + G G +G Sbjct: 1165 GLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGEN 1224 Query: 2231 GPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGE---PGPKGGIGNR 2287 G GP GPPG G +G GP G+ G G PG G G +G KGEPGE PGP G G Sbjct: 1225 GDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVG 1284 Query: 2288 GPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSG 2347 GP+GE G+ G G G G G +G PG GPKGNPG G G GP G G G G Sbjct: 1285 GPKGERGEKGE--AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDG 1342 Query: 2348 PPGIVGQKGDPGYPGPAGPKGNRG 2371 G G+ GDPG PGP GP G G Sbjct: 1343 VGGDKGEDGDPGQPGPPGPSGEAG 1366 Score = 283 bits (723), Expect = 2e-75 Identities = 171/388 (44%), Positives = 200/388 (51%), Gaps = 56/388 (14%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNG---------TQGFQGCP 2088 GQ+G +G G GP G PG G G PG GG GE GP G G +GF G P Sbjct: 1147 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPP 1206 Query: 2089 GQRGVKGSRGFPGEKGEVGEIGL------------DGLDGEDGDKGLPGSSG------EK 2130 G G++G G PGEKGE G++G G +G DG +G PGS G EK Sbjct: 1207 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1266 Query: 2131 GNPGRRGDKGPRGE------KGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGR 2184 G PG G+ GP GE KGERG+ G G PG G G KG GD GP G PG Sbjct: 1267 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP----GAKGPPGDDGPKGNPGP 1322 Query: 2185 DGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGE 2244 G PG PG G+ G G+ G G KG G PGQPG G G G GP G GPPG G Sbjct: 1323 VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGA 1382 Query: 2245 QGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGE------TGDDGR 2298 +G G +G+ G AGA G G+TGP+G +G G+PGP+G G GP GE G DG Sbjct: 1383 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP 1442 Query: 2299 DG-------VGSEGRRGKKGERGFPGY------PGPKGNPGEPGLNGTTGPKGIRGRRGN 2345 G G +G G KGE+G PG PG +G G+ GL GT G G +G G Sbjct: 1443 PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGI 1502 Query: 2346 SGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373 GP G +G G PG PGP GPKGN+G + Sbjct: 1503 PGPAGPLGPPGPPGLPGPQGPKGNKGST 1530 Score = 282 bits (722), Expect = 3e-75 Identities = 172/377 (45%), Positives = 196/377 (51%), Gaps = 35/377 (9%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGD------EGGPGERGPPGVNGTQGFQGCPGQR 2091 G RG GP G IG +G+PG G +G GD G PG RGP G NG G QG PG Sbjct: 1198 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV 1257 Query: 2092 GVKGSRGFPGEKGEVG------EIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEK 2145 G G G GE GE G E G+ G GE G+KG G G G PG +G G G K Sbjct: 1258 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK 1317 Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP 2205 G G VG GDPG PG+ G G GD G G PG+ G PG GE G G G+RGP Sbjct: 1318 GNPGPVGFPGDPGPPGEPGPA-GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGP 1376 Query: 2206 PGA------KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGA 2259 PGA +G KG G+ G EG G G GP GPAG PG G +GI GP G G GA Sbjct: 1377 PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1436 Query: 2260 PGERGRTGPLGR------KGEPGEPGPKGG---IGNRGPRGETGDDGRDGV-GSEGRRGK 2309 G+ G GP+G KG+PG G KG IG GP GE G+ G G+ G++G G Sbjct: 1437 AGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGA 1496 Query: 2310 KGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGN 2369 KG+ G PG GP G PG PGL G GPK GN G G GQKGD G PGP G G Sbjct: 1497 KGDGGIPGPAGPLGPPGPPGLPGPQGPK------GNKGSTGPAGQKGDSGLPGPPGSPGP 1550 Query: 2370 RGDSIDQCALIQSIKDK 2386 G+ I ++ S K + Sbjct: 1551 PGEVIQPLPILSSKKTR 1567 Score = 278 bits (712), Expect = 5e-74 Identities = 164/366 (44%), Positives = 191/366 (52%), Gaps = 32/366 (8%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096 SG G +GP G GP G G+ G RG PG +GG G G PG G +GF G PG G KG Sbjct: 567 SGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGH 626 Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGD---KGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI 2153 RG G +G G G DG+ GEDG+ +GLPG +G +G G RG G G+ G G G Sbjct: 627 RGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP 686 Query: 2154 RGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKG 2213 G GN G E GP G+ G+ GP G+PG G G PGE G G G G PGA G G Sbjct: 687 PGPKGNMGPQG-EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPG 745 Query: 2214 GPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE----------- 2262 PG+ G GE+G G GP GP G PG G +G G RG G+ G GE Sbjct: 746 HPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG 805 Query: 2263 ----RGRTGPLGRKGEPGEPGPK---GGIGNRGPRGETGDDGRDGV----GSEGRRGKKG 2311 RG G +G +GE G GPK G G+ GP G+ G+ G+ GV G GR+G KG Sbjct: 806 LKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKG 865 Query: 2312 ERGFPGYPGPKGN------PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAG 2365 GFPG+PG G G+PG G GP G RG RG GP G G KG G GP G Sbjct: 866 STGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPG 925 Query: 2366 PKGNRG 2371 P G RG Sbjct: 926 PPGERG 931 Score = 276 bits (707), Expect = 2e-73 Identities = 170/387 (43%), Positives = 200/387 (51%), Gaps = 30/387 (7%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPG---DEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094 G G+RG G+ GP G+PG G +G PG ++G PGE+GP G G G QG G G Sbjct: 1069 GSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPA 1128 Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKG---------LPGSSGEKGNPGRRGDKGPRGEK 2145 G G PGE G+ GEIG G G GDKG L G G G G G+ GPRG++ Sbjct: 1129 GPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQ 1188 Query: 2146 G---ERGDVGIRGDPGNPGQDSQER-----GPKGETGDLGPMGVPGRDGVPGGPGETGKN 2197 G ++GD G RG PG PG + G KGE GD+GPMG PG PG G G N Sbjct: 1189 GMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP---PGPRGPQGPN 1245 Query: 2198 GGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAA 2257 G G +GPPG+ G+ GG G+ G GE G G G AG GP G GE+G +GP G+ G Sbjct: 1246 GADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP 1305 Query: 2258 GAPGERGRTGPLGRKGE---PGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGER 2313 GA G G GP G G PG+PGP G G G G GD G DG G G G GE Sbjct: 1306 GAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEA 1365 Query: 2314 GFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGI---VGQKGDPGYPGPAGPKGNR 2370 G PG PG +G PG G G G KG +G G GPPG VG +G G PGP G +G Sbjct: 1366 GPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIP 1425 Query: 2371 GDSIDQCALIQSIKDKCPCCYGPLECP 2397 G +Q + +D P GP P Sbjct: 1426 GPVGEQGLPGAAGQDGPPGPMGPPGLP 1452 Score = 276 bits (706), Expect = 2e-73 Identities = 155/340 (45%), Positives = 186/340 (54%), Gaps = 27/340 (7%) Query: 2047 GSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEV 2106 G GP G+ G G G PG G GE G PG G +G QG PG G G RG PG G Sbjct: 541 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 600 Query: 2107 GEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE 2166 G G G G+ G GLPG G+KG+ RG++GP+G G GD G+RG+ G E Sbjct: 601 GMPGEPGAKGDRGFDGLPGLPGDKGH---RGERGPQGPPGPPGDDGMRGEDG-------E 650 Query: 2167 RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGT 2226 GP+G G+ GP G+ G G PG PG+ G G G GP G G +G PG PG +G G Sbjct: 651 IGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 710 Query: 2227 RGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGN 2286 +G GP GP GPPG G QG G G GA G PG G+ G G KG G PGP+G IG Sbjct: 711 QGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGY 770 Query: 2287 RGPRGETGDDGRDGVGSEGRRGKKGERGFPGY------PGPKGNPGEPGLNGTTGPKGIR 2340 GPRG G DG G+ +G +G+KGE GFPG+ G +G G+ G G GP+G + Sbjct: 771 PGPRGVKGADGVRGL--KGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPK 828 Query: 2341 GRRGNSGPPGIVGQKGD---------PGYPGPAGPKGNRG 2371 GR G +G PG GQ G+ PGYPG GPKG+ G Sbjct: 829 GRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTG 868 Score = 266 bits (681), Expect = 2e-70 Identities = 165/388 (42%), Positives = 190/388 (48%), Gaps = 54/388 (13%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G +G GP G GP G GE G G PG G PG +GP G G GF G G++G +G Sbjct: 826 GPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA 885 Query: 2098 GFPGEKGEVGEIG------LDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR------GEK 2145 G PG +G+ G G G G+ G KG G G G PG RG +GP+ G K Sbjct: 886 GKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPK 945 Query: 2146 GERGDVGIRGDPGNPGQDSQER--------------GPKGETGDLGPMGVPGRDGVPGGP 2191 G G G G PG+PGQ + GP+G TG+ GP+G G G PG P Sbjct: 946 GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 1005 Query: 2192 GE------TGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQ---------GPAGPA 2236 GE GK G G GP G G G G GF GE+G GAQ GP GP Sbjct: 1006 GEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPP 1065 Query: 2237 GPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDD 2296 GP G GE+G +G G G G PG +G GP G KG PGE GP+G G G +G G Sbjct: 1066 GPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLP 1125 Query: 2297 GRDG-VGSEGRRGKKGERGFPGYPGPKGN------PGEPGLNGTTGPKGIRGRRGNSGP- 2348 G G GS G G KGE G PG G KG+ PG PGL G G GI G G GP Sbjct: 1126 GPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPR 1185 Query: 2349 --PGIVGQKGDP---GYPGPAGPKGNRG 2371 G+ GQKGD G+PGP GP G +G Sbjct: 1186 GQQGMFGQKGDEGARGFPGPPGPIGLQG 1213 Score = 262 bits (670), Expect = 3e-69 Identities = 156/351 (44%), Positives = 186/351 (52%), Gaps = 19/351 (5%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGD---EGGPGERGPPGVNGTQGFQGCPGQRGVK 2094 G +G RG G GP G PG+DG RG G+ G PGE GP G+ G +G G PGQ G+ Sbjct: 622 GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 681 Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154 G G PG KG +G G G G+ G+ G G G +G G G+KGP+G+ G G G Sbjct: 682 GVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 741 Query: 2155 GDPGNPGQDSQ--ERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP---PGAK 2209 G PG+PG++ Q E+G G G GP+G PG GV G G G G G +G PG K Sbjct: 742 GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 801 Query: 2210 GNKGGPGQPGFEGEQGTRGAQGPAGP---AGPPGLIGEQGISGPRGSGGAAGAPGERGRT 2266 G+ G G G G+ G RG GP GP AGP G G G +G +G G G PG GR Sbjct: 802 GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQ 861 Query: 2267 GPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGN-- 2324 GP G G PG PG G G RG G+ G G+ G G RG +G RG G PGPKG Sbjct: 862 GPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR--GPTGPRGSRGARGPTGKPGPKGTSG 919 Query: 2325 ----PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 PG PG G GP+G G G GPPG G+ G PG+PG G G +G Sbjct: 920 GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 970 Score = 261 bits (666), Expect = 1e-68 Identities = 164/386 (42%), Positives = 197/386 (51%), Gaps = 40/386 (10%) Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIG------------PKGIPGEDGYRGYPGDEG----- 2068 EK GVP G G +GP GS G +G+ G+ G RG G G Sbjct: 845 EKGKLGVP-GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSR 903 Query: 2069 ---GP-GERGPPGVNGTQGFQGCPGQRGVKGSR---GFPGEKGEVGEIGLDGLDGEDGDK 2121 GP G+ GP G +G G G PG+RG +G + GFPG KG G G DGL G G + Sbjct: 904 GARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQR 963 Query: 2122 GLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE-----RGPKGETGDL 2176 G G G+ G PG G GP+G GE G +G RG PG PG ++ G +G GD Sbjct: 964 GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 1023 Query: 2177 GPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPA 2236 GP G+ G+DG G G G+ G G +G PG KG +G G PG G G RG+ G AGP Sbjct: 1024 GPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPI 1083 Query: 2237 GPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDD 2296 G PG G Q GP G G GAPGE+G GP GR G G G G G G GE GD Sbjct: 1084 GLPGRPGPQ---GPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1140 Query: 2297 GRDG-VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355 G G G +G +G KGE G PG PG +G G PG+ G G G RG++G G G G + Sbjct: 1141 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1200 Query: 2356 GDPGYPGP------AGPKGNRGDSID 2375 G PG PGP GP G +G++ D Sbjct: 1201 GFPGPPGPIGLQGLPGPPGEKGENGD 1226 Score = 233 bits (595), Expect = 2e-60 Identities = 144/350 (41%), Positives = 172/350 (49%), Gaps = 33/350 (9%) Query: 2044 GPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK--------- 2094 GP G GP GI G G +G G G PG+RGPPG G G G PG G Sbjct: 454 GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGG 513 Query: 2095 -GSRG--FPGEKGEVGEI---GLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER 2148 GS+G ++ + I L G G GL G G G PG G KG G+ G + Sbjct: 514 DGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ 573 Query: 2149 GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208 G G++G PG P G+ G G G G G+PG PG G G G G PG Sbjct: 574 GPRGVQGPPG----------PTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 623 Query: 2209 KGNKG--GP-GQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGR 2265 KG++G GP G PG G+ G RG G GP G PG G +G+ GPRG+ GA G PG G Sbjct: 624 KGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV 683 Query: 2266 TGPLGRKGE---PGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPK 2322 GP G KG GEPGP G GN GP+G G G +G G +G +G+ G G PG Sbjct: 684 DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGP--IGPPGEKGPQGKPGLAGLPGAD 741 Query: 2323 GNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 G PG PG G +G KG G G GP G G +G G G G KG++G+ Sbjct: 742 GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 791 Score = 219 bits (559), Expect = 3e-56 Identities = 142/353 (40%), Positives = 167/353 (47%), Gaps = 51/353 (14%) Query: 2048 SIGPKGIPGEDGYRGYPGD-EGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEV 2106 SI G GE G +G P E G GPPG G G G PG +G G G PG++G Sbjct: 427 SINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPP 486 Query: 2107 GEIGLDGLDGEDGDKG----LPGSSGEKGNPGR--------------------RGDKGPR 2142 G GL G DG G G LP G G+ G RG GP Sbjct: 487 GRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPM 546 Query: 2143 GEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGR 2202 G G G VG G G G+ S + GP+G G GP PG G PG G G +GG G Sbjct: 547 GLTGRPGPVGGPGSSGAKGE-SGDPGPQGPRGVQGP---PGPTGKPGKRGRPGADGGRGM 602 Query: 2203 RGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE 2262 G PGAKG++G G PG G++G RG +GP GP GPP G G Sbjct: 603 PGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP------------------GDDGM 644 Query: 2263 RGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGP 2321 RG G +G +G PGE GP+G +G RG G G G GV G G +G G +G PG PG Sbjct: 645 RGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQ 704 Query: 2322 KGNPGEPGLNGTTGPKGIRGRRGNSGPPGIV---GQKGDPGYPGPAGPKGNRG 2371 +GNPG GL G GP G G +G G PG+ G G PG+PG G G +G Sbjct: 705 QGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 757 Score = 208 bits (530), Expect = 6e-53 Identities = 117/275 (42%), Positives = 146/275 (53%), Gaps = 17/275 (6%) Query: 2027 KACCGVPCKCSGQRGDRGPIGSIGP---KGIPGEDGYRGYPGDEGGPGERGPPG------ 2077 +A G P G++G+ GP G+ GP KG PG+DG +G PG G PG+ GPPG Sbjct: 1280 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAG 1339 Query: 2078 ---VNGTQGFQGCPGQRGV---KGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKG 2131 V G +G G PGQ G G G PG G+ G G G +G G+KG G +G +G Sbjct: 1340 QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEG 1399 Query: 2132 NPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE--RGPKGETGDLGPMGVPGRDGVPG 2189 PG+ G GP+G G+ G G+RG PG G+ G G G +GP G+PG G PG Sbjct: 1400 PPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPG 1459 Query: 2190 GPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISG 2249 GE G G G GPPG +G KG G PG +G G +G G GPAGP G G G+ G Sbjct: 1460 SKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPG 1519 Query: 2250 PRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGI 2284 P+G G G+ G G+ G G G PG PGP G + Sbjct: 1520 PQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1554 Score = 186 bits (473), Expect = 2e-46 Identities = 131/333 (39%), Positives = 155/333 (46%), Gaps = 26/333 (7%) Query: 2057 EDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPG--EKGEVGEIGLDGL 2114 ED P +E GPG P + T+ G G KG +G P E G + E G G Sbjct: 402 EDKPTSPPNEEFGPGV--PAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVE-GPPGP 458 Query: 2115 DGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNP-------GQDSQER 2167 G G G PG G G PG GD+GP G G G G+ G PG G D + Sbjct: 459 AGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGS-K 517 Query: 2168 GPKGETGDLGPMGV--PGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQG 2225 GP + + R + G PG G G R GP G G+ G G+ G G QG Sbjct: 518 GPTISAQEAQAQAILQQARIALRGPPGPMGLTG---RPGPVGGPGSSGAKGESGDPGPQG 574 Query: 2226 TRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERG---RTGPLGRKGEPGEPGPKG 2282 RG QGP GP G PG G G G RG G GA G+RG G G KG GE GP+G Sbjct: 575 PRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQG 634 Query: 2283 GIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGR 2342 G G G G+DG +G G G+ G RG G G G PG+PG+ G GP G +G Sbjct: 635 PPGPPGDDGMRGEDGE--IGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGN 692 Query: 2343 RGNSGPPGIVGQKGDP---GYPGPAGPKGNRGD 2372 G G PG GQ+G+P G PGP GP G G+ Sbjct: 693 MGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGE 725 Score = 158 bits (399), Expect = 9e-38 Identities = 100/240 (41%), Positives = 120/240 (50%), Gaps = 17/240 (7%) Query: 2140 GPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGG 2199 G GEKG++G+ + +PG GP G G G MG PG G G PG+ G G Sbjct: 432 GAYGEKGQKGEPAVV-EPG-----MLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGP 485 Query: 2200 FGRRGPPGAKGNKGGPGQ----PGFEGEQGTRGAQGPAGPAGPPGLIGEQGIS--GPRGS 2253 GR G PGA G G PG P G G++G A A ++ + I+ GP G Sbjct: 486 PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGP 545 Query: 2254 GGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGER 2313 G G PG G G G KGE G+PGP+G G +GP G TG G+ GR G G R Sbjct: 546 MGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGK-----RGRPGADGGR 600 Query: 2314 GFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373 G PG PG KG+ G GL G G KG RG RG GPPG G G G G GP+G G++ Sbjct: 601 GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 660 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 289 bits (739), Expect = 3e-77 Identities = 170/401 (42%), Positives = 205/401 (51%), Gaps = 71/401 (17%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERG---------------PPGVNGTQ 2082 G G++GP G G G+PG DG G+PG EG GE+G P GV G Sbjct: 670 GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGAD 729 Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142 G +G G +G KG GFPG KG++G G G G+ G +G G G KG G GD GP Sbjct: 730 GVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPS 789 Query: 2143 GEKGERGDVGIRGDPGNPGQDSQERGPKGET---------GDLGPMGVPGRDGVPGGPGE 2193 G+ GE+G +G+ G PG PG+ +GPKG T G+ G GV G+ G G G Sbjct: 790 GQAGEKGKLGVPGLPGYPGR----QGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP 845 Query: 2194 TGKNGGFGRRGP---PGAKGNKGGPGQPGFEGEQGTRGAQGPA---GPAGPPGLIGE--- 2244 TG G G RGP PG KG GG G PG GE+G +G QGP GP GPPG G+ Sbjct: 846 TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL 905 Query: 2245 ------------QGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGP------------ 2280 QG +GP G GG G G G TGP+G +G PG PGP Sbjct: 906 PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 965 Query: 2281 KGGIGNRGPRGETGDDGRDGV----------GSEGRRGKKGERGFPGYPGPKGNPGEPGL 2330 +G G+ GP+G +G DG G+ G++G G KG G G PGP G+PGE G Sbjct: 966 EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGS 1025 Query: 2331 NGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 GT GP G+ GR G GPPG G+KG PG GP GP G G Sbjct: 1026 AGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1066 Score = 286 bits (731), Expect = 3e-76 Identities = 164/353 (46%), Positives = 194/353 (54%), Gaps = 20/353 (5%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDG---YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094 G+ G GP G +GP+G GE G RG+PG G PGE+G PG G +G +G PG +G+ Sbjct: 919 GKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGIS 978 Query: 2095 GS------RGFPGEKGEVGEIGLDGLDGEDGDKGLPG---SSGEKGNPGRRGDKGPRGEK 2145 G RGFPGE+G G G GL G +G +G PG S GE+G+ G G G G Sbjct: 979 GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRP 1038 Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP 2205 G +G G G+ G PG+ + GP G G GP+G+PG G G PGE G G G G Sbjct: 1039 GPQGPPGPAGEKGAPGEKGPQ-GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ 1097 Query: 2206 PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE--- 2262 G+KG+KG G PG G QG GA G AG G PG G+QG+ G +G GA G PG Sbjct: 1098 KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP 1157 Query: 2263 ---RGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGY 2318 +G GP G KGE G+ GP G G GPRG G +G DG G G G G G G Sbjct: 1158 IGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1217 Query: 2319 PGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 PG GNPG PG G GPKG RG +G +GPPG G G G PG GPKGN G Sbjct: 1218 PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPG 1270 Score = 284 bits (726), Expect = 1e-75 Identities = 163/384 (42%), Positives = 195/384 (50%), Gaps = 52/384 (13%) Query: 2038 GQRGDRGPIGSIG---PKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQG---FQGCPGQR 2091 G G+ GPIG G P G PGE G G G EG G+ GP G++G G +G PG+R Sbjct: 934 GPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGER 993 Query: 2092 GVKGSR------------------GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNP 2133 G+ G++ G PGE+G G G GL G G +G PG +GEKG P Sbjct: 994 GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1053 Query: 2134 GRRGDKGPRGEKGERGDVGI---------------RGDPGNPGQ-----DSQERGPKGET 2173 G +G +GP G G +G VG+ +G+ G PGQ D E GP G Sbjct: 1054 GEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP 1113 Query: 2174 GDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFE---GEQGTRGAQ 2230 G GP+G PG G G PG G+ G FG++G GA+G G PG G + G G +G Sbjct: 1114 GLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGEN 1173 Query: 2231 GPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGE---PGPKGGIGNR 2287 G GP GPPG G +G GP G+ G G PG G G +G KGEPGE PGP G G Sbjct: 1174 GDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVG 1233 Query: 2288 GPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSG 2347 GP+GE G+ G G G G G +G PG GPKGNPG G G GP G G G G Sbjct: 1234 GPKGERGEKGE--AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDG 1291 Query: 2348 PPGIVGQKGDPGYPGPAGPKGNRG 2371 G G+ GDPG PGP GP G G Sbjct: 1292 VGGDKGEDGDPGQPGPPGPSGEAG 1315 Score = 283 bits (723), Expect = 2e-75 Identities = 171/388 (44%), Positives = 200/388 (51%), Gaps = 56/388 (14%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNG---------TQGFQGCP 2088 GQ+G +G G GP G PG G G PG GG GE GP G G +GF G P Sbjct: 1096 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPP 1155 Query: 2089 GQRGVKGSRGFPGEKGEVGEIGL------------DGLDGEDGDKGLPGSSG------EK 2130 G G++G G PGEKGE G++G G +G DG +G PGS G EK Sbjct: 1156 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1215 Query: 2131 GNPGRRGDKGPRGE------KGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGR 2184 G PG G+ GP GE KGERG+ G G PG G G KG GD GP G PG Sbjct: 1216 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP----GAKGPPGDDGPKGNPGP 1271 Query: 2185 DGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGE 2244 G PG PG G+ G G+ G G KG G PGQPG G G G GP G GPPG G Sbjct: 1272 VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGA 1331 Query: 2245 QGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGE------TGDDGR 2298 +G G +G+ G AGA G G+TGP+G +G G+PGP+G G GP GE G DG Sbjct: 1332 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP 1391 Query: 2299 DG-------VGSEGRRGKKGERGFPGY------PGPKGNPGEPGLNGTTGPKGIRGRRGN 2345 G G +G G KGE+G PG PG +G G+ GL GT G G +G G Sbjct: 1392 PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGI 1451 Query: 2346 SGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373 GP G +G G PG PGP GPKGN+G + Sbjct: 1452 PGPAGPLGPPGPPGLPGPQGPKGNKGST 1479 Score = 282 bits (722), Expect = 3e-75 Identities = 172/377 (45%), Positives = 196/377 (51%), Gaps = 35/377 (9%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGD------EGGPGERGPPGVNGTQGFQGCPGQR 2091 G RG GP G IG +G+PG G +G GD G PG RGP G NG G QG PG Sbjct: 1147 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV 1206 Query: 2092 GVKGSRGFPGEKGEVG------EIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEK 2145 G G G GE GE G E G+ G GE G+KG G G G PG +G G G K Sbjct: 1207 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK 1266 Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP 2205 G G VG GDPG PG+ G G GD G G PG+ G PG GE G G G+RGP Sbjct: 1267 GNPGPVGFPGDPGPPGEPGPA-GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGP 1325 Query: 2206 PGA------KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGA 2259 PGA +G KG G+ G EG G G GP GPAG PG G +GI GP G G GA Sbjct: 1326 PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1385 Query: 2260 PGERGRTGPLGR------KGEPGEPGPKGG---IGNRGPRGETGDDGRDGV-GSEGRRGK 2309 G+ G GP+G KG+PG G KG IG GP GE G+ G G+ G++G G Sbjct: 1386 AGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGA 1445 Query: 2310 KGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGN 2369 KG+ G PG GP G PG PGL G GPK GN G G GQKGD G PGP G G Sbjct: 1446 KGDGGIPGPAGPLGPPGPPGLPGPQGPK------GNKGSTGPAGQKGDSGLPGPPGSPGP 1499 Query: 2370 RGDSIDQCALIQSIKDK 2386 G+ I ++ S K + Sbjct: 1500 PGEVIQPLPILSSKKTR 1516 Score = 278 bits (712), Expect = 5e-74 Identities = 164/366 (44%), Positives = 191/366 (52%), Gaps = 32/366 (8%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096 SG G +GP G GP G G+ G RG PG +GG G G PG G +GF G PG G KG Sbjct: 516 SGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGH 575 Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGD---KGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI 2153 RG G +G G G DG+ GEDG+ +GLPG +G +G G RG G G+ G G G Sbjct: 576 RGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP 635 Query: 2154 RGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKG 2213 G GN G E GP G+ G+ GP G+PG G G PGE G G G G PGA G G Sbjct: 636 PGPKGNMGPQG-EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPG 694 Query: 2214 GPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE----------- 2262 PG+ G GE+G G GP GP G PG G +G G RG G+ G GE Sbjct: 695 HPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG 754 Query: 2263 ----RGRTGPLGRKGEPGEPGPK---GGIGNRGPRGETGDDGRDGV----GSEGRRGKKG 2311 RG G +G +GE G GPK G G+ GP G+ G+ G+ GV G GR+G KG Sbjct: 755 LKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKG 814 Query: 2312 ERGFPGYPGPKGN------PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAG 2365 GFPG+PG G G+PG G GP G RG RG GP G G KG G GP G Sbjct: 815 STGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPG 874 Query: 2366 PKGNRG 2371 P G RG Sbjct: 875 PPGERG 880 Score = 276 bits (707), Expect = 2e-73 Identities = 170/387 (43%), Positives = 200/387 (51%), Gaps = 30/387 (7%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPG---DEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094 G G+RG G+ GP G+PG G +G PG ++G PGE+GP G G G QG G G Sbjct: 1018 GSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPA 1077 Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKG---------LPGSSGEKGNPGRRGDKGPRGEK 2145 G G PGE G+ GEIG G G GDKG L G G G G G+ GPRG++ Sbjct: 1078 GPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQ 1137 Query: 2146 G---ERGDVGIRGDPGNPGQDSQER-----GPKGETGDLGPMGVPGRDGVPGGPGETGKN 2197 G ++GD G RG PG PG + G KGE GD+GPMG PG PG G G N Sbjct: 1138 GMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP---PGPRGPQGPN 1194 Query: 2198 GGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAA 2257 G G +GPPG+ G+ GG G+ G GE G G G AG GP G GE+G +GP G+ G Sbjct: 1195 GADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP 1254 Query: 2258 GAPGERGRTGPLGRKGE---PGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGER 2313 GA G G GP G G PG+PGP G G G G GD G DG G G G GE Sbjct: 1255 GAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEA 1314 Query: 2314 GFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGI---VGQKGDPGYPGPAGPKGNR 2370 G PG PG +G PG G G G KG +G G GPPG VG +G G PGP G +G Sbjct: 1315 GPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIP 1374 Query: 2371 GDSIDQCALIQSIKDKCPCCYGPLECP 2397 G +Q + +D P GP P Sbjct: 1375 GPVGEQGLPGAAGQDGPPGPMGPPGLP 1401 Score = 276 bits (706), Expect = 2e-73 Identities = 155/340 (45%), Positives = 186/340 (54%), Gaps = 27/340 (7%) Query: 2047 GSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEV 2106 G GP G+ G G G PG G GE G PG G +G QG PG G G RG PG G Sbjct: 490 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 549 Query: 2107 GEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE 2166 G G G G+ G GLPG G+KG+ RG++GP+G G GD G+RG+ G E Sbjct: 550 GMPGEPGAKGDRGFDGLPGLPGDKGH---RGERGPQGPPGPPGDDGMRGEDG-------E 599 Query: 2167 RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGT 2226 GP+G G+ GP G+ G G PG PG+ G G G GP G G +G PG PG +G G Sbjct: 600 IGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 659 Query: 2227 RGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGN 2286 +G GP GP GPPG G QG G G GA G PG G+ G G KG G PGP+G IG Sbjct: 660 QGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGY 719 Query: 2287 RGPRGETGDDGRDGVGSEGRRGKKGERGFPGY------PGPKGNPGEPGLNGTTGPKGIR 2340 GPRG G DG G+ +G +G+KGE GFPG+ G +G G+ G G GP+G + Sbjct: 720 PGPRGVKGADGVRGL--KGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPK 777 Query: 2341 GRRGNSGPPGIVGQKGD---------PGYPGPAGPKGNRG 2371 GR G +G PG GQ G+ PGYPG GPKG+ G Sbjct: 778 GRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTG 817 Score = 266 bits (681), Expect = 2e-70 Identities = 165/388 (42%), Positives = 190/388 (48%), Gaps = 54/388 (13%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G +G GP G GP G GE G G PG G PG +GP G G GF G G++G +G Sbjct: 775 GPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA 834 Query: 2098 GFPGEKGEVGEIG------LDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR------GEK 2145 G PG +G+ G G G G+ G KG G G G PG RG +GP+ G K Sbjct: 835 GKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPK 894 Query: 2146 GERGDVGIRGDPGNPGQDSQER--------------GPKGETGDLGPMGVPGRDGVPGGP 2191 G G G G PG+PGQ + GP+G TG+ GP+G G G PG P Sbjct: 895 GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 954 Query: 2192 GE------TGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQ---------GPAGPA 2236 GE GK G G GP G G G G GF GE+G GAQ GP GP Sbjct: 955 GEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPP 1014 Query: 2237 GPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDD 2296 GP G GE+G +G G G G PG +G GP G KG PGE GP+G G G +G G Sbjct: 1015 GPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLP 1074 Query: 2297 GRDG-VGSEGRRGKKGERGFPGYPGPKGN------PGEPGLNGTTGPKGIRGRRGNSGP- 2348 G G GS G G KGE G PG G KG+ PG PGL G G GI G G GP Sbjct: 1075 GPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPR 1134 Query: 2349 --PGIVGQKGDP---GYPGPAGPKGNRG 2371 G+ GQKGD G+PGP GP G +G Sbjct: 1135 GQQGMFGQKGDEGARGFPGPPGPIGLQG 1162 Score = 262 bits (670), Expect = 3e-69 Identities = 156/351 (44%), Positives = 186/351 (52%), Gaps = 19/351 (5%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGD---EGGPGERGPPGVNGTQGFQGCPGQRGVK 2094 G +G RG G GP G PG+DG RG G+ G PGE GP G+ G +G G PGQ G+ Sbjct: 571 GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 630 Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154 G G PG KG +G G G G+ G+ G G G +G G G+KGP+G+ G G G Sbjct: 631 GVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 690 Query: 2155 GDPGNPGQDSQ--ERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP---PGAK 2209 G PG+PG++ Q E+G G G GP+G PG GV G G G G G +G PG K Sbjct: 691 GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 750 Query: 2210 GNKGGPGQPGFEGEQGTRGAQGPAGP---AGPPGLIGEQGISGPRGSGGAAGAPGERGRT 2266 G+ G G G G+ G RG GP GP AGP G G G +G +G G G PG GR Sbjct: 751 GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQ 810 Query: 2267 GPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGN-- 2324 GP G G PG PG G G RG G+ G G+ G G RG +G RG G PGPKG Sbjct: 811 GPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR--GPTGPRGSRGARGPTGKPGPKGTSG 868 Query: 2325 ----PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 PG PG G GP+G G G GPPG G+ G PG+PG G G +G Sbjct: 869 GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 919 Score = 261 bits (666), Expect = 1e-68 Identities = 164/386 (42%), Positives = 197/386 (51%), Gaps = 40/386 (10%) Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIG------------PKGIPGEDGYRGYPGDEG----- 2068 EK GVP G G +GP GS G +G+ G+ G RG G G Sbjct: 794 EKGKLGVP-GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSR 852 Query: 2069 ---GP-GERGPPGVNGTQGFQGCPGQRGVKGSR---GFPGEKGEVGEIGLDGLDGEDGDK 2121 GP G+ GP G +G G G PG+RG +G + GFPG KG G G DGL G G + Sbjct: 853 GARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQR 912 Query: 2122 GLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE-----RGPKGETGDL 2176 G G G+ G PG G GP+G GE G +G RG PG PG ++ G +G GD Sbjct: 913 GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 972 Query: 2177 GPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPA 2236 GP G+ G+DG G G G+ G G +G PG KG +G G PG G G RG+ G AGP Sbjct: 973 GPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPI 1032 Query: 2237 GPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDD 2296 G PG G Q GP G G GAPGE+G GP GR G G G G G G GE GD Sbjct: 1033 GLPGRPGPQ---GPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1089 Query: 2297 GRDG-VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355 G G G +G +G KGE G PG PG +G G PG+ G G G RG++G G G G + Sbjct: 1090 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1149 Query: 2356 GDPGYPGP------AGPKGNRGDSID 2375 G PG PGP GP G +G++ D Sbjct: 1150 GFPGPPGPIGLQGLPGPPGEKGENGD 1175 Score = 233 bits (595), Expect = 2e-60 Identities = 144/350 (41%), Positives = 172/350 (49%), Gaps = 33/350 (9%) Query: 2044 GPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK--------- 2094 GP G GP GI G G +G G G PG+RGPPG G G G PG G Sbjct: 403 GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGG 462 Query: 2095 -GSRG--FPGEKGEVGEI---GLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER 2148 GS+G ++ + I L G G GL G G G PG G KG G+ G + Sbjct: 463 DGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ 522 Query: 2149 GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208 G G++G PG P G+ G G G G G+PG PG G G G G PG Sbjct: 523 GPRGVQGPPG----------PTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 572 Query: 2209 KGNKG--GP-GQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGR 2265 KG++G GP G PG G+ G RG G GP G PG G +G+ GPRG+ GA G PG G Sbjct: 573 KGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV 632 Query: 2266 TGPLGRKGE---PGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPK 2322 GP G KG GEPGP G GN GP+G G G +G G +G +G+ G G PG Sbjct: 633 DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGP--IGPPGEKGPQGKPGLAGLPGAD 690 Query: 2323 GNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 G PG PG G +G KG G G GP G G +G G G G KG++G+ Sbjct: 691 GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 740 Score = 219 bits (559), Expect = 3e-56 Identities = 142/353 (40%), Positives = 167/353 (47%), Gaps = 51/353 (14%) Query: 2048 SIGPKGIPGEDGYRGYPGD-EGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEV 2106 SI G GE G +G P E G GPPG G G G PG +G G G PG++G Sbjct: 376 SINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPP 435 Query: 2107 GEIGLDGLDGEDGDKG----LPGSSGEKGNPGR--------------------RGDKGPR 2142 G GL G DG G G LP G G+ G RG GP Sbjct: 436 GRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPM 495 Query: 2143 GEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGR 2202 G G G VG G G G+ S + GP+G G GP PG G PG G G +GG G Sbjct: 496 GLTGRPGPVGGPGSSGAKGE-SGDPGPQGPRGVQGP---PGPTGKPGKRGRPGADGGRGM 551 Query: 2203 RGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE 2262 G PGAKG++G G PG G++G RG +GP GP GPP G G Sbjct: 552 PGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP------------------GDDGM 593 Query: 2263 RGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGP 2321 RG G +G +G PGE GP+G +G RG G G G GV G G +G G +G PG PG Sbjct: 594 RGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQ 653 Query: 2322 KGNPGEPGLNGTTGPKGIRGRRGNSGPPGIV---GQKGDPGYPGPAGPKGNRG 2371 +GNPG GL G GP G G +G G PG+ G G PG+PG G G +G Sbjct: 654 QGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 706 Score = 208 bits (530), Expect = 6e-53 Identities = 117/275 (42%), Positives = 146/275 (53%), Gaps = 17/275 (6%) Query: 2027 KACCGVPCKCSGQRGDRGPIGSIGP---KGIPGEDGYRGYPGDEGGPGERGPPG------ 2077 +A G P G++G+ GP G+ GP KG PG+DG +G PG G PG+ GPPG Sbjct: 1229 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAG 1288 Query: 2078 ---VNGTQGFQGCPGQRGV---KGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKG 2131 V G +G G PGQ G G G PG G+ G G G +G G+KG G +G +G Sbjct: 1289 QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEG 1348 Query: 2132 NPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE--RGPKGETGDLGPMGVPGRDGVPG 2189 PG+ G GP+G G+ G G+RG PG G+ G G G +GP G+PG G PG Sbjct: 1349 PPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPG 1408 Query: 2190 GPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISG 2249 GE G G G GPPG +G KG G PG +G G +G G GPAGP G G G+ G Sbjct: 1409 SKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPG 1468 Query: 2250 PRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGI 2284 P+G G G+ G G+ G G G PG PGP G + Sbjct: 1469 PQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1503 Score = 186 bits (473), Expect = 2e-46 Identities = 131/333 (39%), Positives = 155/333 (46%), Gaps = 26/333 (7%) Query: 2057 EDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPG--EKGEVGEIGLDGL 2114 ED P +E GPG P + T+ G G KG +G P E G + E G G Sbjct: 351 EDKPTSPPNEEFGPGV--PAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVE-GPPGP 407 Query: 2115 DGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNP-------GQDSQER 2167 G G G PG G G PG GD+GP G G G G+ G PG G D + Sbjct: 408 AGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGS-K 466 Query: 2168 GPKGETGDLGPMGV--PGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQG 2225 GP + + R + G PG G G R GP G G+ G G+ G G QG Sbjct: 467 GPTISAQEAQAQAILQQARIALRGPPGPMGLTG---RPGPVGGPGSSGAKGESGDPGPQG 523 Query: 2226 TRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERG---RTGPLGRKGEPGEPGPKG 2282 RG QGP GP G PG G G G RG G GA G+RG G G KG GE GP+G Sbjct: 524 PRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQG 583 Query: 2283 GIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGR 2342 G G G G+DG +G G G+ G RG G G G PG+PG+ G GP G +G Sbjct: 584 PPGPPGDDGMRGEDGE--IGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGN 641 Query: 2343 RGNSGPPGIVGQKGDP---GYPGPAGPKGNRGD 2372 G G PG GQ+G+P G PGP GP G G+ Sbjct: 642 MGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGE 674 Score = 158 bits (399), Expect = 9e-38 Identities = 100/240 (41%), Positives = 120/240 (50%), Gaps = 17/240 (7%) Query: 2140 GPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGG 2199 G GEKG++G+ + +PG GP G G G MG PG G G PG+ G G Sbjct: 381 GAYGEKGQKGEPAVV-EPG-----MLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGP 434 Query: 2200 FGRRGPPGAKGNKGGPGQ----PGFEGEQGTRGAQGPAGPAGPPGLIGEQGIS--GPRGS 2253 GR G PGA G G PG P G G++G A A ++ + I+ GP G Sbjct: 435 PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGP 494 Query: 2254 GGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGER 2313 G G PG G G G KGE G+PGP+G G +GP G TG G+ GR G G R Sbjct: 495 MGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGK-----RGRPGADGGR 549 Query: 2314 GFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373 G PG PG KG+ G GL G G KG RG RG GPPG G G G G GP+G G++ Sbjct: 550 GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 609 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 289 bits (739), Expect = 3e-77 Identities = 170/401 (42%), Positives = 205/401 (51%), Gaps = 71/401 (17%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERG---------------PPGVNGTQ 2082 G G++GP G G G+PG DG G+PG EG GE+G P GV G Sbjct: 709 GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGAD 768 Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142 G +G G +G KG GFPG KG++G G G G+ G +G G G KG G GD GP Sbjct: 769 GVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPS 828 Query: 2143 GEKGERGDVGIRGDPGNPGQDSQERGPKGET---------GDLGPMGVPGRDGVPGGPGE 2193 G+ GE+G +G+ G PG PG+ +GPKG T G+ G GV G+ G G G Sbjct: 829 GQAGEKGKLGVPGLPGYPGR----QGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP 884 Query: 2194 TGKNGGFGRRGP---PGAKGNKGGPGQPGFEGEQGTRGAQGPA---GPAGPPGLIGE--- 2244 TG G G RGP PG KG GG G PG GE+G +G QGP GP GPPG G+ Sbjct: 885 TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL 944 Query: 2245 ------------QGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGP------------ 2280 QG +GP G GG G G G TGP+G +G PG PGP Sbjct: 945 PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 1004 Query: 2281 KGGIGNRGPRGETGDDGRDGV----------GSEGRRGKKGERGFPGYPGPKGNPGEPGL 2330 +G G+ GP+G +G DG G+ G++G G KG G G PGP G+PGE G Sbjct: 1005 EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGS 1064 Query: 2331 NGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 GT GP G+ GR G GPPG G+KG PG GP GP G G Sbjct: 1065 AGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1105 Score = 286 bits (731), Expect = 3e-76 Identities = 164/353 (46%), Positives = 194/353 (54%), Gaps = 20/353 (5%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDG---YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094 G+ G GP G +GP+G GE G RG+PG G PGE+G PG G +G +G PG +G+ Sbjct: 958 GKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGIS 1017 Query: 2095 GS------RGFPGEKGEVGEIGLDGLDGEDGDKGLPG---SSGEKGNPGRRGDKGPRGEK 2145 G RGFPGE+G G G GL G +G +G PG S GE+G+ G G G G Sbjct: 1018 GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRP 1077 Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP 2205 G +G G G+ G PG+ + GP G G GP+G+PG G G PGE G G G G Sbjct: 1078 GPQGPPGPAGEKGAPGEKGPQ-GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ 1136 Query: 2206 PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE--- 2262 G+KG+KG G PG G QG GA G AG G PG G+QG+ G +G GA G PG Sbjct: 1137 KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP 1196 Query: 2263 ---RGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGY 2318 +G GP G KGE G+ GP G G GPRG G +G DG G G G G G G Sbjct: 1197 IGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1256 Query: 2319 PGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 PG GNPG PG G GPKG RG +G +GPPG G G G PG GPKGN G Sbjct: 1257 PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPG 1309 Score = 284 bits (726), Expect = 1e-75 Identities = 163/384 (42%), Positives = 195/384 (50%), Gaps = 52/384 (13%) Query: 2038 GQRGDRGPIGSIG---PKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQG---FQGCPGQR 2091 G G+ GPIG G P G PGE G G G EG G+ GP G++G G +G PG+R Sbjct: 973 GPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGER 1032 Query: 2092 GVKGSR------------------GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNP 2133 G+ G++ G PGE+G G G GL G G +G PG +GEKG P Sbjct: 1033 GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1092 Query: 2134 GRRGDKGPRGEKGERGDVGI---------------RGDPGNPGQ-----DSQERGPKGET 2173 G +G +GP G G +G VG+ +G+ G PGQ D E GP G Sbjct: 1093 GEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP 1152 Query: 2174 GDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFE---GEQGTRGAQ 2230 G GP+G PG G G PG G+ G FG++G GA+G G PG G + G G +G Sbjct: 1153 GLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGEN 1212 Query: 2231 GPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGE---PGPKGGIGNR 2287 G GP GPPG G +G GP G+ G G PG G G +G KGEPGE PGP G G Sbjct: 1213 GDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVG 1272 Query: 2288 GPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSG 2347 GP+GE G+ G G G G G +G PG GPKGNPG G G GP G G G G Sbjct: 1273 GPKGERGEKGE--AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDG 1330 Query: 2348 PPGIVGQKGDPGYPGPAGPKGNRG 2371 G G+ GDPG PGP GP G G Sbjct: 1331 VGGDKGEDGDPGQPGPPGPSGEAG 1354 Score = 283 bits (723), Expect = 2e-75 Identities = 171/388 (44%), Positives = 200/388 (51%), Gaps = 56/388 (14%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNG---------TQGFQGCP 2088 GQ+G +G G GP G PG G G PG GG GE GP G G +GF G P Sbjct: 1135 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPP 1194 Query: 2089 GQRGVKGSRGFPGEKGEVGEIGL------------DGLDGEDGDKGLPGSSG------EK 2130 G G++G G PGEKGE G++G G +G DG +G PGS G EK Sbjct: 1195 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1254 Query: 2131 GNPGRRGDKGPRGE------KGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGR 2184 G PG G+ GP GE KGERG+ G G PG G G KG GD GP G PG Sbjct: 1255 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP----GAKGPPGDDGPKGNPGP 1310 Query: 2185 DGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGE 2244 G PG PG G+ G G+ G G KG G PGQPG G G G GP G GPPG G Sbjct: 1311 VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGA 1370 Query: 2245 QGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGE------TGDDGR 2298 +G G +G+ G AGA G G+TGP+G +G G+PGP+G G GP GE G DG Sbjct: 1371 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP 1430 Query: 2299 DG-------VGSEGRRGKKGERGFPGY------PGPKGNPGEPGLNGTTGPKGIRGRRGN 2345 G G +G G KGE+G PG PG +G G+ GL GT G G +G G Sbjct: 1431 PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGI 1490 Query: 2346 SGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373 GP G +G G PG PGP GPKGN+G + Sbjct: 1491 PGPAGPLGPPGPPGLPGPQGPKGNKGST 1518 Score = 282 bits (722), Expect = 3e-75 Identities = 172/377 (45%), Positives = 196/377 (51%), Gaps = 35/377 (9%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGD------EGGPGERGPPGVNGTQGFQGCPGQR 2091 G RG GP G IG +G+PG G +G GD G PG RGP G NG G QG PG Sbjct: 1186 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV 1245 Query: 2092 GVKGSRGFPGEKGEVG------EIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEK 2145 G G G GE GE G E G+ G GE G+KG G G G PG +G G G K Sbjct: 1246 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK 1305 Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP 2205 G G VG GDPG PG+ G G GD G G PG+ G PG GE G G G+RGP Sbjct: 1306 GNPGPVGFPGDPGPPGEPGPA-GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGP 1364 Query: 2206 PGA------KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGA 2259 PGA +G KG G+ G EG G G GP GPAG PG G +GI GP G G GA Sbjct: 1365 PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1424 Query: 2260 PGERGRTGPLGR------KGEPGEPGPKGG---IGNRGPRGETGDDGRDGV-GSEGRRGK 2309 G+ G GP+G KG+PG G KG IG GP GE G+ G G+ G++G G Sbjct: 1425 AGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGA 1484 Query: 2310 KGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGN 2369 KG+ G PG GP G PG PGL G GPK GN G G GQKGD G PGP G G Sbjct: 1485 KGDGGIPGPAGPLGPPGPPGLPGPQGPK------GNKGSTGPAGQKGDSGLPGPPGSPGP 1538 Query: 2370 RGDSIDQCALIQSIKDK 2386 G+ I ++ S K + Sbjct: 1539 PGEVIQPLPILSSKKTR 1555 Score = 278 bits (712), Expect = 5e-74 Identities = 164/366 (44%), Positives = 191/366 (52%), Gaps = 32/366 (8%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096 SG G +GP G GP G G+ G RG PG +GG G G PG G +GF G PG G KG Sbjct: 555 SGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGH 614 Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGD---KGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI 2153 RG G +G G G DG+ GEDG+ +GLPG +G +G G RG G G+ G G G Sbjct: 615 RGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP 674 Query: 2154 RGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKG 2213 G GN G E GP G+ G+ GP G+PG G G PGE G G G G PGA G G Sbjct: 675 PGPKGNMGPQG-EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPG 733 Query: 2214 GPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE----------- 2262 PG+ G GE+G G GP GP G PG G +G G RG G+ G GE Sbjct: 734 HPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG 793 Query: 2263 ----RGRTGPLGRKGEPGEPGPK---GGIGNRGPRGETGDDGRDGV----GSEGRRGKKG 2311 RG G +G +GE G GPK G G+ GP G+ G+ G+ GV G GR+G KG Sbjct: 794 LKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKG 853 Query: 2312 ERGFPGYPGPKGN------PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAG 2365 GFPG+PG G G+PG G GP G RG RG GP G G KG G GP G Sbjct: 854 STGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPG 913 Query: 2366 PKGNRG 2371 P G RG Sbjct: 914 PPGERG 919 Score = 276 bits (707), Expect = 2e-73 Identities = 170/387 (43%), Positives = 200/387 (51%), Gaps = 30/387 (7%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPG---DEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094 G G+RG G+ GP G+PG G +G PG ++G PGE+GP G G G QG G G Sbjct: 1057 GSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPA 1116 Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKG---------LPGSSGEKGNPGRRGDKGPRGEK 2145 G G PGE G+ GEIG G G GDKG L G G G G G+ GPRG++ Sbjct: 1117 GPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQ 1176 Query: 2146 G---ERGDVGIRGDPGNPGQDSQER-----GPKGETGDLGPMGVPGRDGVPGGPGETGKN 2197 G ++GD G RG PG PG + G KGE GD+GPMG PG PG G G N Sbjct: 1177 GMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP---PGPRGPQGPN 1233 Query: 2198 GGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAA 2257 G G +GPPG+ G+ GG G+ G GE G G G AG GP G GE+G +GP G+ G Sbjct: 1234 GADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP 1293 Query: 2258 GAPGERGRTGPLGRKGE---PGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGER 2313 GA G G GP G G PG+PGP G G G G GD G DG G G G GE Sbjct: 1294 GAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEA 1353 Query: 2314 GFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGI---VGQKGDPGYPGPAGPKGNR 2370 G PG PG +G PG G G G KG +G G GPPG VG +G G PGP G +G Sbjct: 1354 GPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIP 1413 Query: 2371 GDSIDQCALIQSIKDKCPCCYGPLECP 2397 G +Q + +D P GP P Sbjct: 1414 GPVGEQGLPGAAGQDGPPGPMGPPGLP 1440 Score = 276 bits (706), Expect = 2e-73 Identities = 155/340 (45%), Positives = 186/340 (54%), Gaps = 27/340 (7%) Query: 2047 GSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEV 2106 G GP G+ G G G PG G GE G PG G +G QG PG G G RG PG G Sbjct: 529 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 588 Query: 2107 GEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE 2166 G G G G+ G GLPG G+KG+ RG++GP+G G GD G+RG+ G E Sbjct: 589 GMPGEPGAKGDRGFDGLPGLPGDKGH---RGERGPQGPPGPPGDDGMRGEDG-------E 638 Query: 2167 RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGT 2226 GP+G G+ GP G+ G G PG PG+ G G G GP G G +G PG PG +G G Sbjct: 639 IGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 698 Query: 2227 RGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGN 2286 +G GP GP GPPG G QG G G GA G PG G+ G G KG G PGP+G IG Sbjct: 699 QGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGY 758 Query: 2287 RGPRGETGDDGRDGVGSEGRRGKKGERGFPGY------PGPKGNPGEPGLNGTTGPKGIR 2340 GPRG G DG G+ +G +G+KGE GFPG+ G +G G+ G G GP+G + Sbjct: 759 PGPRGVKGADGVRGL--KGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPK 816 Query: 2341 GRRGNSGPPGIVGQKGD---------PGYPGPAGPKGNRG 2371 GR G +G PG GQ G+ PGYPG GPKG+ G Sbjct: 817 GRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTG 856 Score = 266 bits (681), Expect = 2e-70 Identities = 165/388 (42%), Positives = 190/388 (48%), Gaps = 54/388 (13%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G +G GP G GP G GE G G PG G PG +GP G G GF G G++G +G Sbjct: 814 GPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA 873 Query: 2098 GFPGEKGEVGEIG------LDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR------GEK 2145 G PG +G+ G G G G+ G KG G G G PG RG +GP+ G K Sbjct: 874 GKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPK 933 Query: 2146 GERGDVGIRGDPGNPGQDSQER--------------GPKGETGDLGPMGVPGRDGVPGGP 2191 G G G G PG+PGQ + GP+G TG+ GP+G G G PG P Sbjct: 934 GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 993 Query: 2192 GE------TGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQ---------GPAGPA 2236 GE GK G G GP G G G G GF GE+G GAQ GP GP Sbjct: 994 GEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPP 1053 Query: 2237 GPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDD 2296 GP G GE+G +G G G G PG +G GP G KG PGE GP+G G G +G G Sbjct: 1054 GPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLP 1113 Query: 2297 GRDG-VGSEGRRGKKGERGFPGYPGPKGN------PGEPGLNGTTGPKGIRGRRGNSGP- 2348 G G GS G G KGE G PG G KG+ PG PGL G G GI G G GP Sbjct: 1114 GPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPR 1173 Query: 2349 --PGIVGQKGDP---GYPGPAGPKGNRG 2371 G+ GQKGD G+PGP GP G +G Sbjct: 1174 GQQGMFGQKGDEGARGFPGPPGPIGLQG 1201 Score = 262 bits (670), Expect = 3e-69 Identities = 156/351 (44%), Positives = 186/351 (52%), Gaps = 19/351 (5%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGD---EGGPGERGPPGVNGTQGFQGCPGQRGVK 2094 G +G RG G GP G PG+DG RG G+ G PGE GP G+ G +G G PGQ G+ Sbjct: 610 GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 669 Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154 G G PG KG +G G G G+ G+ G G G +G G G+KGP+G+ G G G Sbjct: 670 GVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 729 Query: 2155 GDPGNPGQDSQ--ERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP---PGAK 2209 G PG+PG++ Q E+G G G GP+G PG GV G G G G G +G PG K Sbjct: 730 GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 789 Query: 2210 GNKGGPGQPGFEGEQGTRGAQGPAGP---AGPPGLIGEQGISGPRGSGGAAGAPGERGRT 2266 G+ G G G G+ G RG GP GP AGP G G G +G +G G G PG GR Sbjct: 790 GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQ 849 Query: 2267 GPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGN-- 2324 GP G G PG PG G G RG G+ G G+ G G RG +G RG G PGPKG Sbjct: 850 GPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR--GPTGPRGSRGARGPTGKPGPKGTSG 907 Query: 2325 ----PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 PG PG G GP+G G G GPPG G+ G PG+PG G G +G Sbjct: 908 GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 958 Score = 261 bits (666), Expect = 1e-68 Identities = 164/386 (42%), Positives = 197/386 (51%), Gaps = 40/386 (10%) Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIG------------PKGIPGEDGYRGYPGDEG----- 2068 EK GVP G G +GP GS G +G+ G+ G RG G G Sbjct: 833 EKGKLGVP-GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSR 891 Query: 2069 ---GP-GERGPPGVNGTQGFQGCPGQRGVKGSR---GFPGEKGEVGEIGLDGLDGEDGDK 2121 GP G+ GP G +G G G PG+RG +G + GFPG KG G G DGL G G + Sbjct: 892 GARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQR 951 Query: 2122 GLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE-----RGPKGETGDL 2176 G G G+ G PG G GP+G GE G +G RG PG PG ++ G +G GD Sbjct: 952 GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 1011 Query: 2177 GPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPA 2236 GP G+ G+DG G G G+ G G +G PG KG +G G PG G G RG+ G AGP Sbjct: 1012 GPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPI 1071 Query: 2237 GPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDD 2296 G PG G Q GP G G GAPGE+G GP GR G G G G G G GE GD Sbjct: 1072 GLPGRPGPQ---GPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1128 Query: 2297 GRDG-VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355 G G G +G +G KGE G PG PG +G G PG+ G G G RG++G G G G + Sbjct: 1129 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1188 Query: 2356 GDPGYPGP------AGPKGNRGDSID 2375 G PG PGP GP G +G++ D Sbjct: 1189 GFPGPPGPIGLQGLPGPPGEKGENGD 1214 Score = 233 bits (595), Expect = 2e-60 Identities = 144/350 (41%), Positives = 172/350 (49%), Gaps = 33/350 (9%) Query: 2044 GPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK--------- 2094 GP G GP GI G G +G G G PG+RGPPG G G G PG G Sbjct: 442 GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGG 501 Query: 2095 -GSRG--FPGEKGEVGEI---GLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER 2148 GS+G ++ + I L G G GL G G G PG G KG G+ G + Sbjct: 502 DGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ 561 Query: 2149 GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208 G G++G PG P G+ G G G G G+PG PG G G G G PG Sbjct: 562 GPRGVQGPPG----------PTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 611 Query: 2209 KGNKG--GP-GQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGR 2265 KG++G GP G PG G+ G RG G GP G PG G +G+ GPRG+ GA G PG G Sbjct: 612 KGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV 671 Query: 2266 TGPLGRKGE---PGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPK 2322 GP G KG GEPGP G GN GP+G G G +G G +G +G+ G G PG Sbjct: 672 DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGP--IGPPGEKGPQGKPGLAGLPGAD 729 Query: 2323 GNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 G PG PG G +G KG G G GP G G +G G G G KG++G+ Sbjct: 730 GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 779 Score = 219 bits (559), Expect = 3e-56 Identities = 142/353 (40%), Positives = 167/353 (47%), Gaps = 51/353 (14%) Query: 2048 SIGPKGIPGEDGYRGYPGD-EGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEV 2106 SI G GE G +G P E G GPPG G G G PG +G G G PG++G Sbjct: 415 SINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPP 474 Query: 2107 GEIGLDGLDGEDGDKG----LPGSSGEKGNPGR--------------------RGDKGPR 2142 G GL G DG G G LP G G+ G RG GP Sbjct: 475 GRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPM 534 Query: 2143 GEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGR 2202 G G G VG G G G+ S + GP+G G GP PG G PG G G +GG G Sbjct: 535 GLTGRPGPVGGPGSSGAKGE-SGDPGPQGPRGVQGP---PGPTGKPGKRGRPGADGGRGM 590 Query: 2203 RGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE 2262 G PGAKG++G G PG G++G RG +GP GP GPP G G Sbjct: 591 PGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP------------------GDDGM 632 Query: 2263 RGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGP 2321 RG G +G +G PGE GP+G +G RG G G G GV G G +G G +G PG PG Sbjct: 633 RGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQ 692 Query: 2322 KGNPGEPGLNGTTGPKGIRGRRGNSGPPGIV---GQKGDPGYPGPAGPKGNRG 2371 +GNPG GL G GP G G +G G PG+ G G PG+PG G G +G Sbjct: 693 QGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 745 Score = 208 bits (530), Expect = 6e-53 Identities = 117/275 (42%), Positives = 146/275 (53%), Gaps = 17/275 (6%) Query: 2027 KACCGVPCKCSGQRGDRGPIGSIGP---KGIPGEDGYRGYPGDEGGPGERGPPG------ 2077 +A G P G++G+ GP G+ GP KG PG+DG +G PG G PG+ GPPG Sbjct: 1268 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAG 1327 Query: 2078 ---VNGTQGFQGCPGQRGV---KGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKG 2131 V G +G G PGQ G G G PG G+ G G G +G G+KG G +G +G Sbjct: 1328 QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEG 1387 Query: 2132 NPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE--RGPKGETGDLGPMGVPGRDGVPG 2189 PG+ G GP+G G+ G G+RG PG G+ G G G +GP G+PG G PG Sbjct: 1388 PPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPG 1447 Query: 2190 GPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISG 2249 GE G G G GPPG +G KG G PG +G G +G G GPAGP G G G+ G Sbjct: 1448 SKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPG 1507 Query: 2250 PRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGI 2284 P+G G G+ G G+ G G G PG PGP G + Sbjct: 1508 PQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1542 Score = 186 bits (473), Expect = 2e-46 Identities = 131/333 (39%), Positives = 155/333 (46%), Gaps = 26/333 (7%) Query: 2057 EDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPG--EKGEVGEIGLDGL 2114 ED P +E GPG P + T+ G G KG +G P E G + E G G Sbjct: 390 EDKPTSPPNEEFGPGV--PAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVE-GPPGP 446 Query: 2115 DGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNP-------GQDSQER 2167 G G G PG G G PG GD+GP G G G G+ G PG G D + Sbjct: 447 AGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGS-K 505 Query: 2168 GPKGETGDLGPMGV--PGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQG 2225 GP + + R + G PG G G R GP G G+ G G+ G G QG Sbjct: 506 GPTISAQEAQAQAILQQARIALRGPPGPMGLTG---RPGPVGGPGSSGAKGESGDPGPQG 562 Query: 2226 TRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERG---RTGPLGRKGEPGEPGPKG 2282 RG QGP GP G PG G G G RG G GA G+RG G G KG GE GP+G Sbjct: 563 PRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQG 622 Query: 2283 GIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGR 2342 G G G G+DG +G G G+ G RG G G G PG+PG+ G GP G +G Sbjct: 623 PPGPPGDDGMRGEDGE--IGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGN 680 Query: 2343 RGNSGPPGIVGQKGDP---GYPGPAGPKGNRGD 2372 G G PG GQ+G+P G PGP GP G G+ Sbjct: 681 MGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGE 713 Score = 158 bits (399), Expect = 9e-38 Identities = 100/240 (41%), Positives = 120/240 (50%), Gaps = 17/240 (7%) Query: 2140 GPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGG 2199 G GEKG++G+ + +PG GP G G G MG PG G G PG+ G G Sbjct: 420 GAYGEKGQKGEPAVV-EPG-----MLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGP 473 Query: 2200 FGRRGPPGAKGNKGGPGQ----PGFEGEQGTRGAQGPAGPAGPPGLIGEQGIS--GPRGS 2253 GR G PGA G G PG P G G++G A A ++ + I+ GP G Sbjct: 474 PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGP 533 Query: 2254 GGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGER 2313 G G PG G G G KGE G+PGP+G G +GP G TG G+ GR G G R Sbjct: 534 MGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGK-----RGRPGADGGR 588 Query: 2314 GFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373 G PG PG KG+ G GL G G KG RG RG GPPG G G G G GP+G G++ Sbjct: 589 GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 648 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 286 bits (733), Expect = 2e-76 Identities = 159/344 (46%), Positives = 184/344 (53%), Gaps = 23/344 (6%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G G GPIGS GP+G PG+ G G PG G PGE GF G PG RG G+ Sbjct: 243 GDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGE---------VGFAGSPGARGFPGAP 293 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157 G PG KG G GL+G GE G G G +G G G G GPRG GERG +G +G P Sbjct: 294 GLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAP 353 Query: 2158 GNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQ 2217 G G G G+ G +GP+G+PG G PG PG G+ G G RGP G +G +G G Sbjct: 354 GQRGA----HGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGP 409 Query: 2218 PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGE 2277 PG G G GA G G G G G G SGP GS G G+PG +G TGP G +G+PG+ Sbjct: 410 PGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGD 469 Query: 2278 PGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGP---------KGNPGE 2327 PG G G GP+GE G G G +G G GK+G RG PG GP GN G Sbjct: 470 PGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGF 529 Query: 2328 PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 PG +G GPKG +G RG G G G +GDPG PG G G RG Sbjct: 530 PGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARG 573 Score = 283 bits (725), Expect = 1e-75 Identities = 161/369 (43%), Positives = 187/369 (50%), Gaps = 30/369 (8%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRG 2092 P +G G GP GS GP+GI G+ G G PG +G G +G PG +G QG G PG+ G Sbjct: 442 PPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEG 501 Query: 2093 VKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVG 2152 +G RG PG G G +G G G G G G G KG G RG G G KG +GD G Sbjct: 502 KRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPG 561 Query: 2153 IRGDPGNPGQDSQERGP--KGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKG 2210 G+PG PG P +G G LGP+G PG DG PG PG G G G G PG KG Sbjct: 562 RPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKG 621 Query: 2211 NKGGPGQPGFEGEQGTRGAQ---------GPAGPAGPPGLIGEQGISGPRGSGGAAGAPG 2261 + G PG+PG G G G + GP+GP GPPGL GE+G GP G G G PG Sbjct: 622 SSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPG 681 Query: 2262 ERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGR----------------DGVGSEG 2305 G G G+ G+ G PG G +G GPRGE G+ G G G +G Sbjct: 682 PPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDG 741 Query: 2306 RRGKKGERGFPGYPGP---KGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPG 2362 +G G G PG GP +G PGE G+ GT GPKG RG G G G G G G PG Sbjct: 742 PKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPG 801 Query: 2363 PAGPKGNRG 2371 P GP G G Sbjct: 802 PLGPPGPAG 810 Score = 282 bits (722), Expect = 3e-75 Identities = 164/370 (44%), Positives = 188/370 (50%), Gaps = 38/370 (10%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQG---CPGQRGVK 2094 G +G+ GP G+ GP+G G+ G G PG G PG G G +GT G +G PG G Sbjct: 384 GMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPP 443 Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGE---KGNPGRRGDKGPRGEKGERGDV 2151 GS G PG G G G G+ G+ GD G+PG GE KG PG G +GP G GE G Sbjct: 444 GSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKR 503 Query: 2152 GIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGN 2211 G RGDPG G GP GE G G G PG DG+PG G G+ G G GP G++G+ Sbjct: 504 GPRGDPGTVGPP----GPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGD 559 Query: 2212 KGGPGQPGFEGEQ---GTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2268 G PG+PG G + G G QGP G GP G GE G GP GS G G PG G GP Sbjct: 560 PGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGP 619 Query: 2269 LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG----------VGSEGRRGKKGERGFPGY 2318 G G+PG+PG G G G RG G DG G G G +G G GF G Sbjct: 620 KGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGL 679 Query: 2319 PGPKGNPGE------------PGLNGTTGPKGIRGRRGNSGPPGIV---GQKGDPGYPGP 2363 PGP G PGE PG G GP+G RG G G PGI G+KG G GP Sbjct: 680 PGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGP 739 Query: 2364 AGPKGNRGDS 2373 GPKG+ G S Sbjct: 740 DGPKGSPGPS 749 Score = 282 bits (721), Expect = 4e-75 Identities = 166/378 (43%), Positives = 193/378 (51%), Gaps = 31/378 (8%) Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGT---Q 2082 E+ G P G +GDRG IG G +G G DG RG PG G PG GP G G + Sbjct: 766 ERGIAGTP----GPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPR 821 Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGN---------- 2132 G G PG RG GSRG G G VG G G DG+ G KG PG G+KG+ Sbjct: 822 GLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLA 881 Query: 2133 --PGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQ--ERGPKGETGDLGPMGVPGRDGVP 2188 PG G G G KG RG G G G PG + GP G G GP+G PG++G P Sbjct: 882 GSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPP 941 Query: 2189 GGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGIS 2248 G G+ G +G G RGP G G G G PG +G+ G G GPAG G G++G G Sbjct: 942 GLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQR 1001 Query: 2249 GPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRR 2307 G RG G G G G+ GP G G+ G PGP G G+ GP GE G +G G G+ GR Sbjct: 1002 GERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRD 1061 Query: 2308 GKKGERGFPGYPGPKGNPGEPGLNGTTGP---------KGIRGRRGNSGPPGIVGQKGDP 2358 G GERG G PGP G PG G GT GP +G G RG GPPG G++G P Sbjct: 1062 GAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLP 1121 Query: 2359 GYPGPAGPKGNRGDSIDQ 2376 G GP G KG+ GD D+ Sbjct: 1122 GPQGPRGDKGDHGDRGDR 1139 Score = 281 bits (720), Expect = 6e-75 Identities = 162/360 (45%), Positives = 192/360 (53%), Gaps = 32/360 (8%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGD---EGGPGERGPPGVNGTQGFQGCPGQRG- 2092 +G G +GP G +GP G PGEDG G PG G PG G PG G+ G G PG+ G Sbjct: 575 TGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGN 634 Query: 2093 --VKGSRGFPGEKGEVGE---IGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGE 2147 V G RG PG+ GEVG +G GL GE G++G PG +G +G PG GP GE G+ Sbjct: 635 AGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPG---PPGPPGEGGK 691 Query: 2148 RGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPG 2207 GD G+ GDPG G GP+GE G+ G G PG G+PG G G +G G +G PG Sbjct: 692 PGDQGVPGDPGAVGP----LGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPG 747 Query: 2208 AKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTG 2267 G G G PG +G G RG G GP G G IGE+G G G+ GA G PG G G Sbjct: 748 PSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPG 807 Query: 2268 PLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG----------VGSEGRRGKKGERGFPG 2317 P G GE GEPGP+G +G G RG G G +G G +G+ G KGE G PG Sbjct: 808 PAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPG 867 Query: 2318 Y------PGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 PGP+G G PG +G G G++G RG GPPG G G G GP GP G G Sbjct: 868 QKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPG 927 Score = 277 bits (708), Expect = 1e-73 Identities = 160/347 (46%), Positives = 183/347 (52%), Gaps = 18/347 (5%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPG------ERGPPGVNGTQGFQGCPGQ 2090 SG G GP GS GP+G G G RG PGD G PG +G PG +G QG G PG+ Sbjct: 440 SGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGE 499 Query: 2091 RGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD 2150 G +G RG PG G G +G G G G G G G KG G RG G G KG +GD Sbjct: 500 EGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGD 559 Query: 2151 VGIRGDPGNPGQDSQERGP--KGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208 G G+PG PG P +G G LGP+G PG DG PG PG G G G G PG Sbjct: 560 PGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGP 619 Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2268 KG+ G PG+PG G G G +G PG GE G SGP G G AG GE+G GP Sbjct: 620 KGSSGDPGKPGEAGNAGVPGQRGA------PGKDGEVGPSGPVGPPGLAGERGEQGPPGP 673 Query: 2269 LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGE 2327 G +G PG PGP G G G +G GD G G +G G RG GERG PG G G G Sbjct: 674 TGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGM 733 Query: 2328 PGLNGTTGPKGI---RGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 G +G GPKG G G++GPPG+ G G+ G G GPKG+RG Sbjct: 734 AGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRG 780 Score = 275 bits (704), Expect = 4e-73 Identities = 158/359 (44%), Positives = 183/359 (50%), Gaps = 28/359 (7%) Query: 2037 SGQRGDRGPIGSIGPK------GIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQ 2090 +G G+ G GS G + G+PG G+RG+ G EG GE G PG G G G G Sbjct: 272 NGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGA 331 Query: 2091 RGVKGSRGFPGEKGEV---------GEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGP 2141 G G RG PGE+G + G G+ G G G G+PGSSG GNPG +G+ GP Sbjct: 332 MGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGP 391 Query: 2142 RGEKGERGDVGIRGDPGNPGQDSQER-----GPKGETGDLGPMGVPGRDGVPGGPGETGK 2196 G +G G G RG+ G PG G G G GP G PG G PG G G Sbjct: 392 TGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGS 451 Query: 2197 NGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGA 2256 G G GP G +G G PG PGF+GE G +G GP G GP G GE+G GPRG G Sbjct: 452 PGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGT 511 Query: 2257 AGAPGERGRTGPLGRKGEPGE---PGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGER 2313 G PG G G G +G PG PGPKG G RGP G +G GS+G G+ GE Sbjct: 512 VGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPK-----GSQGDPGRPGEP 566 Query: 2314 GFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 G PG G GNPG G G GP G G G GPPG +G +G PG G GPKG+ GD Sbjct: 567 GLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGD 625 Score = 275 bits (704), Expect = 4e-73 Identities = 155/347 (44%), Positives = 179/347 (51%), Gaps = 8/347 (2%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRG 2092 P GQRG G G GP G G G G+PG+ G GE GP G G +G QG G+ G Sbjct: 349 PQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETG 408 Query: 2093 VKGSRGFPGEKGEVGEIGLDGLDGEDGDKGL---PGSSGEKGNPGRRGDKGPRGEKGERG 2149 G G PG G +G G G G G G PGS+G G+PG +G GP+G +G+ G Sbjct: 409 PPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPG 468 Query: 2150 DVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAK 2209 D G+ G G G E GP G G +GP G G+ G G PG G G G RG PG + Sbjct: 469 DPGVPGFKGEAGPKG-EPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNR 527 Query: 2210 GNKGGPGQPGFEGEQGTR---GAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRT 2266 G G G PG +G QG R G+ GP G G PG GE G+ G RG G G G G+ Sbjct: 528 GFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKL 587 Query: 2267 GPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNP 2325 GPLG GE G PGP G IG RG G G G G G G+ G+ G G PG G G Sbjct: 588 GPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKD 647 Query: 2326 GEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 GE G +G GP G+ G RG GPPG G +G PG PGP G G GD Sbjct: 648 GEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGD 694 Score = 272 bits (695), Expect = 4e-72 Identities = 163/380 (42%), Positives = 190/380 (50%), Gaps = 36/380 (9%) Query: 2033 PCKCSGQRGDRGPIGSIGPK------------GIPGEDGYRGYPGDEGGPGERGPPGVN- 2079 P G G+RG G+ GPK G G DG RG PG G PG GP G Sbjct: 757 PPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKG 816 Query: 2080 --GTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEK------- 2130 G +G G PG RG GSRG G G VG G G DG+ G KG PG G+K Sbjct: 817 EPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPG 876 Query: 2131 -----GNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQ--ERGPKGETGDLGPMGVPG 2183 G+PG G G G KG RG G G G PG + GP G G GP+G PG Sbjct: 877 PQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPG 936 Query: 2184 RDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIG 2243 ++G PG G+ G +G G RGP G G G G PG +G+ G G GPAG G G++G Sbjct: 937 KEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVG 996 Query: 2244 EQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VG 2302 G G RG G G G G+ GP G G+ G PGP G G+ GP GE G +G G G Sbjct: 997 MPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDG 1056 Query: 2303 SEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGI------RGRRGNSGPPGIVGQKG 2356 + GR G GERG G PGP G PG G GT GP G RG G+ GP G G+ G Sbjct: 1057 TPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAG 1116 Query: 2357 DPGYPGPAGPKGNRGDSIDQ 2376 G PGP GP+G++GD D+ Sbjct: 1117 KRGLPGPQGPRGDKGDHGDR 1136 Score = 265 bits (677), Expect = 5e-70 Identities = 156/353 (44%), Positives = 187/353 (52%), Gaps = 17/353 (4%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRG---YPGDEGGPGERGPPGVNGTQGFQGCPG 2089 P G G +GP G G KG PGE G +G PG +G G GP G NG G +G G Sbjct: 841 PTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRG 900 Query: 2090 QRGVKGSRGFPGEKGEVGEIGLDGLDG------EDGDKGLPGSSGEKGNPGRRGDKGPRG 2143 +G G+ GFPG G VG G G G E G +G PG G+ G+ GR GD+GP G Sbjct: 901 TQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAG 960 Query: 2144 EKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRR 2203 G GD G G+ G PG D GP G TG G +G+PG+ G G PG G G G+ Sbjct: 961 PPGGPGDKGDPGEDGQPGPDGPP-GPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKV 1019 Query: 2204 GPPGAKGNKGGPGQ---PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAP 2260 GP GA G+KG PG PG G G G +GPAG G PG G G G RG G AG P Sbjct: 1020 GPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLP 1079 Query: 2261 GERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYP 2319 G +G G G G PG+ G +G G+RGP G G G+ G+ G +G RG KG+ G G Sbjct: 1080 GSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDR 1139 Query: 2320 GPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 G KG+ G GL G GP G G +G++G PG G +G PG P GP G G+ Sbjct: 1140 GQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPG---PVGPSGKEGN 1189 Score = 263 bits (673), Expect = 2e-69 Identities = 156/364 (42%), Positives = 179/364 (49%), Gaps = 33/364 (9%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 GQ+GD G G G G PG G G PG +GG G +GPPG G F G G+ G G Sbjct: 867 GQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATG---FPGSAGRVGPPGPA 923 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGL------------PGSSGEKGNPGRRGDKGPRGEK 2145 G PG G +GE G +G G GD G PG G+KG+PG G GP G Sbjct: 924 GAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPP 983 Query: 2146 GERGDVGIRGDPGNPGQDSQER-----GPKGETGDLGPMGVPGRDGVPGGPGETGKNGGF 2200 G G G RG G PGQ + GP G G +GP G G G PG G G NG Sbjct: 984 GPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPV 1043 Query: 2201 GRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAP 2260 G GP G GN G PG+ G GE+G RG GPAG G G G G G G G G P Sbjct: 1044 GEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDP 1103 Query: 2261 GERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-------VGSEGRRGKKGER 2313 G RG GP GR G+ G PGP+G G++G G+ GD G+ G G G G GE+ Sbjct: 1104 GSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQ 1163 Query: 2314 GFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGI------VGQKGDPGYPGPAGPK 2367 G G PGP G G PG G +G +G G G GPPG+ G +G PG PGP GP Sbjct: 1164 GSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPP 1223 Query: 2368 GNRG 2371 G G Sbjct: 1224 GPPG 1227 Score = 262 bits (669), Expect = 5e-69 Identities = 156/363 (42%), Positives = 188/363 (51%), Gaps = 31/363 (8%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 GQ+G+ G + + GI G G G PG +G GERGP G G +G QG G+ GV G Sbjct: 113 GQKGEPGLVPVV--TGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQP 170 Query: 2098 GFPGEKGEVGEIGLDGLD--------GEDGDKGLPGSSG-EKGNPGRRGDKGPRGEKGER 2148 G PG G G DGL G D GL G G+ G G +GP+G +G++ Sbjct: 171 GAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQ 230 Query: 2149 GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208 G G G PG PG + GP G G GP G PG+ G G PG G G G G PGA Sbjct: 231 GGAGPTGPPGEPG----DPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGA 286 Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSG---GAAGAPGERGR 2265 +G G PG PG +G +G +G +GP G G PG GE G +GP G+ G G PGERGR Sbjct: 287 RGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGR 346 Query: 2266 TGPLGRKGE------PGEPGPKGGIGNRGPRGETGDDGRDG----VGSEGRRGKKGERGF 2315 GP G G+ PG+PGP G +G G G G+ G G G+ G G +G+RG Sbjct: 347 LGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGE 406 Query: 2316 PGYPGPKGNPGEP---GLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 G PGP G+PG P G +GT G KG G G SGPPG G G PG G GP+G RG Sbjct: 407 TGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQ 466 Query: 2373 SID 2375 D Sbjct: 467 PGD 469 Score = 208 bits (529), Expect = 8e-53 Identities = 119/284 (41%), Positives = 144/284 (50%), Gaps = 35/284 (12%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGT---QGFQGCPGQRGVK 2094 G G G +G GP G PG G +G PG++G PG GPPG GT +G G PGQRG + Sbjct: 945 GDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGER 1004 Query: 2095 GSRGFPG---------------EKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDK 2139 G G PG +KG G +G G +G G+ G G +G G PGR G Sbjct: 1005 GMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAV 1064 Query: 2140 GPRGEKGERGDVGIRGDPGNPGQ--------DSQERGPKGETGDLGPMGVPGRDGVPGGP 2191 G RG++G+ G G+ G G PG D+ +RG G G +GP G G+ G+PG Sbjct: 1065 GERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQ 1124 Query: 2192 GETGKNGGFGRRGPPGAKGNKGG------PGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQ 2245 G G G G RG G KG++G PG PG GEQG+ G GP GP GPPG +G Sbjct: 1125 GPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPS 1184 Query: 2246 GISGPRGSGGAAGAPGERG---RTGPLGRKGEPGEPGPKGGIGN 2286 G G G G G PG RG GP G GEPG PGP G G+ Sbjct: 1185 GKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGH 1228 Score = 169 bits (429), Expect = 3e-41 Identities = 107/268 (39%), Positives = 125/268 (46%), Gaps = 53/268 (19%) Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGT---- 2081 ++ G+P GQRG+RG G GP G PG+ G G GD+G PG GPPG NG Sbjct: 991 QRGIVGMP----GQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEP 1046 Query: 2082 -----QGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRR 2136 G G PG+ G G RG G+ G G G G G G G PG +G++G+PG R Sbjct: 1047 GPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSR 1106 Query: 2137 GD---------------KGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGV 2181 G +GPRG+KG+ GD RGD RG KG G G G+ Sbjct: 1107 GPIGPPGRAGKRGLPGPQGPRGDKGDHGD---RGD----------RGQKGHRGFTGLQGL 1153 Query: 2182 PGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGL 2241 PG G G G G G FG RGPPG G G G P GP GP GPPG+ Sbjct: 1154 PGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNP------------GPLGPIGPPGV 1201 Query: 2242 IGEQGISGPRGSGGAAGAPGERGRTGPL 2269 G G +GP G G G PG G G L Sbjct: 1202 RGSVGEAGPEGPPGEPGPPGPPGPPGHL 1229 Score = 165 bits (418), Expect = 6e-40 Identities = 108/261 (41%), Positives = 120/261 (45%), Gaps = 40/261 (15%) Query: 2124 PGSSGEKGNPGRRGDKGPRG----EKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPM 2179 PG GR+G KG G G RG G G PG+ G ERGPKG G GP Sbjct: 100 PGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRG-ERGPKGRPGPRGPQ 158 Query: 2180 GVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGP-----AG 2234 G+ DG PG PG+ G PG PG G G P AG Sbjct: 159 GI---DGEPGVPGQ------------------PGAPGPPGHPSHPGPDGLSRPFSAQMAG 197 Query: 2235 PAGPPGLIGEQGIS----GPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPR 2290 GL + G+ GP G G G G++G GP G GEPG+PGP G IG+RGP Sbjct: 198 LDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPE 257 Query: 2291 GETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPG 2350 G G G D G GR G GE GF G PG +G PG PGL G KG RG +G GP G Sbjct: 258 GPPGKPGED--GEPGRNGNPGEVGFAGSPGARGFPGAPGLPGL---KGHRGHKGLEGPKG 312 Query: 2351 IVGQKGDPGYPGPAGPKGNRG 2371 VG G G GP GP G G Sbjct: 313 EVGAPGSKGEAGPTGPMGAMG 333 Score = 62.8 bits (151), Expect = 5e-09 Identities = 46/122 (37%), Positives = 57/122 (46%), Gaps = 19/122 (15%) Query: 2275 PGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGE-------RGFPGYPGPKGNPGE 2327 PGE P + ++ P G + GR GR+G+KGE G G PGP G PG Sbjct: 89 PGECCP---VCSQTPGGGNTNFGR------GRKGQKGEPGLVPVVTGIRGRPGPAGPPGS 139 Query: 2328 PGLNGTTGPKGI---RGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIK 2384 G G GPKG RG +G G PG+ GQ G PG PG G G S A + + Sbjct: 140 QGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLD 199 Query: 2385 DK 2386 +K Sbjct: 200 EK 201 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 286 bits (732), Expect = 2e-76 Identities = 161/346 (46%), Positives = 181/346 (52%), Gaps = 12/346 (3%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGC---PGQRGVK 2094 G G+ G G GPKG G G G GD G PGERGPPG+ G G +G PG G K Sbjct: 648 GPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGK 707 Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154 G+ G PG G G GL G+ GE G G PG G+KG PG G G G+ G RG G Sbjct: 708 GAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPI 767 Query: 2155 GDPGNPGQ--DSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNK 2212 G PG GQ D E G G G GP G PG G G PG G G G+ G PG KG + Sbjct: 768 GPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGER 827 Query: 2213 GGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRK 2272 G PG+ G G G G G +GPAGPPG G +G G G GAAG PG RG GP G Sbjct: 828 GAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSN 887 Query: 2273 GEPGEPGPKGGIGNRGPRGETGDDGRDG----VGSEGRRGKKGERGFPGYPGPKGNPGEP 2328 G PG PGP G G GP G G+ G G G +G G+ GE+G PG GP G PG Sbjct: 888 GNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPL 947 Query: 2329 GLNGTTGPKGIRGRRGNSGP---PGIVGQKGDPGYPGPAGPKGNRG 2371 G+ G TG +G+ G G GP PG G KG+ G PG G G RG Sbjct: 948 GIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERG 993 Score = 284 bits (727), Expect = 9e-76 Identities = 165/361 (45%), Positives = 188/361 (52%), Gaps = 19/361 (5%) Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQ 2085 E G+P +G+RG G G GP GIPGE +G G+ G PG GP G G G Sbjct: 472 EPGANGLP-GAAGERGAPGFRGPAGPNGIPGE---KGPAGERGAPGPAGPRGAAGEPGRD 527 Query: 2086 GCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEK 2145 G PG G++G G PG G G+ G G GE G G PG SG +G PG G GP+G Sbjct: 528 GVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGND 587 Query: 2146 GERGDVGIRGDPGNPGQDSQ-----ERGPKGETGDLGP------MGVPGRDGVPGGPGET 2194 G G G RG PG PG E GP+G G GP G PG G+ G PG Sbjct: 588 GAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTG 647 Query: 2195 GKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSG 2254 G G G+ G PG KG+ G PG PG +G+ G G +GP G AG PGL G G GP G Sbjct: 648 GPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGK 707 Query: 2255 GAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGER 2313 GAAG PG G G G +G PGE G G G +G +GE G G DGV G +G RG G Sbjct: 708 GAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPI 767 Query: 2314 GFP---GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNR 2370 G P G PG KG G PGL G GP+G G RG +GPPG G G PG G G KG R Sbjct: 768 GPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGER 827 Query: 2371 G 2371 G Sbjct: 828 G 828 Score = 280 bits (716), Expect = 2e-74 Identities = 165/364 (45%), Positives = 191/364 (52%), Gaps = 31/364 (8%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGV---- 2093 G G RG G G G+PG G RG G G G+ GPPG GT GF G PG +G Sbjct: 297 GPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPA 356 Query: 2094 --KGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGN---------PGRRGDKGPR 2142 GS G PG++GE G G G G G G+ GS G KG PG G +GP Sbjct: 357 GSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPP 416 Query: 2143 GEKGERGDVGIRGDPGNPGQDSQ--ERGPKGETGDLGPMGVPG------RDGVPGGPGET 2194 G G G G+RG G PG++ E GP+GE G+ G GVPG +DG PG PG Sbjct: 417 GPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGAN 476 Query: 2195 GKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGP---AGPPGLIGEQGISGPR 2251 G G G RG PG +G G G PG +G G RGA GPAGP AG PG G G G R Sbjct: 477 GLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMR 536 Query: 2252 GSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKG 2311 G G+ G PG G+ GP G +GE G PGP G G RG G G G G++G GK G Sbjct: 537 GMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPK--GNDGAPGKNG 594 Query: 2312 ERGFPGYPGPKGNP---GEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKG 2368 ERG PG PGP+G P GE G G GP G G +G++GPPG G +G PG GP G G Sbjct: 595 ERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENG 654 Query: 2369 NRGD 2372 G+ Sbjct: 655 KPGE 658 Score = 279 bits (714), Expect = 3e-74 Identities = 160/375 (42%), Positives = 187/375 (49%), Gaps = 47/375 (12%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096 +G G GP G+IGP G G+DG G PG G G GPPG+ G G G PG +G +G Sbjct: 209 AGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGF 268 Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGD 2156 G GEKGE G GL G +G G+ G PG G +G PG RG G G G RG+ G RG Sbjct: 269 DGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGS 328 Query: 2157 PGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPG 2216 G PG P G G G G PG G G G G NG G+RG PG +G+ G G Sbjct: 329 DGQPG-------PPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQG 381 Query: 2217 QPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPG 2276 PG G G+ G +G GPAG PG G G GP G GA GAPG RG G G+ G G Sbjct: 382 PPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKG 441 Query: 2277 EPGPKGGIGNR---GPRGETGDDGRDGV----------------------------GSEG 2305 EPGP+G G G G G+DG+DG G G Sbjct: 442 EPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPG 501 Query: 2306 RRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGN---------SGPPGIVGQKG 2356 +G GERG PG GP+G GEPG +G G G+RG G+ GPPG G+ G Sbjct: 502 EKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESG 561 Query: 2357 DPGYPGPAGPKGNRG 2371 PG PGP+GP+G G Sbjct: 562 RPGPPGPSGPRGQPG 576 Score = 279 bits (714), Expect = 3e-74 Identities = 165/359 (45%), Positives = 182/359 (50%), Gaps = 30/359 (8%) Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPG------DEGGPGERGPPGVNGTQGF 2084 GVP K G RG GPIG GP G PG+ G G PG G PGERG G G GF Sbjct: 753 GVPGK-DGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGF 811 Query: 2085 QGCPGQRGV---KGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGP 2141 G PGQ G KG RG PGEKGE G G+ G PG SG G PG +G KG Sbjct: 812 PGAPGQNGEPGGKGERGAPGEKGEGGPPGV---------AGPPGGSGPAGPPGPQGVKGE 862 Query: 2142 RGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFG 2201 RG G G G G G PG G G G GP G PG+DG PG G TG G G Sbjct: 863 RGSPGGPGAAGFPGARGLPGPP----GSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPG 918 Query: 2202 RRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPG 2261 GP G G G G PG +G G G G AG G GL G G+ GPRGS G G G Sbjct: 919 VSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKG 978 Query: 2262 ERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-------GSEGRRGKKGERG 2314 E G+ G G GE G PGP+G G G GE G DG G GS G +G +GE G Sbjct: 979 ESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENG 1038 Query: 2315 FPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373 PG PG G+PG PG G G G RG G +GP G G G G PGP GP+G++G++ Sbjct: 1039 SPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGET 1097 Score = 278 bits (711), Expect = 6e-74 Identities = 161/379 (42%), Positives = 190/379 (50%), Gaps = 49/379 (12%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERG---PPGVNGTQGFQGC---PGQR 2091 G+RG+ GP G G G PG++G G G+ G PGE+G PPGV G G G PG + Sbjct: 798 GERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQ 857 Query: 2092 GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDV 2151 GVKG RG PG G G G GL G G G PG G G+PG+ G GP G G G Sbjct: 858 GVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSP 917 Query: 2152 GIRGDPGNPGQDSQE-----RGPKGETGDLG------------------PMGVPGRDGVP 2188 G+ G G+ GQ ++ +GP G G LG P G PG GV Sbjct: 918 GVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVK 977 Query: 2189 GGPGETGKNGGFGRRGPPGAKG------------NKGGPGQPGFEGEQGTRGAQGPAGPA 2236 G G+ G NG G RGPPG +G G PG G G G+ G +G G Sbjct: 978 GESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGEN 1037 Query: 2237 GPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDD 2296 G PG G G GP G G AG G+RG +GP G G PG G +G G +GPRG+ G+ Sbjct: 1038 GSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGE- 1096 Query: 2297 GRDGVGSEGRRGKKGERGFPGYPGPKGNP---GEPGLNGTTGPKGIRGRRGNSGPPGIVG 2353 G G G KG RGFPG PG G+P G+ G G+ GP G RG G SGPPG G Sbjct: 1097 ----TGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDG 1152 Query: 2354 QKGDPGYPGPAGPKGNRGD 2372 G PG GP GP+GNRG+ Sbjct: 1153 TSGHPGPIGPPGPRGNRGE 1171 Score = 271 bits (692), Expect = 1e-71 Identities = 159/396 (40%), Positives = 190/396 (47%), Gaps = 57/396 (14%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G +GD+G G G G+PG+DG RG G G PG G PG +G G PG G+ G R Sbjct: 738 GPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPG---DKGEGGAPGLPGIAGPR 794 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157 G PGE+GE G G G G G G PG GE+G PG +G+ GP G G G G G P Sbjct: 795 GSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPP 854 Query: 2158 GNPGQDSQERGP--KGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGP 2215 G G + P G G G G+PG G G PG G +G G+ GPPG GN G P Sbjct: 855 GPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAP 914 Query: 2216 GQPGFEG------EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPL 2269 G PG G + G +G+ G GP G PG +G GI+G RG G G PG RG GP Sbjct: 915 GSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQ 974 Query: 2270 GRKGEPGEPGPKGGIGNRGP---------RGETGDDGRDGV----------GSEGRRGKK 2310 G KGE G+PG G G RGP G G+ GRDG GS G +G + Sbjct: 975 GVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDR 1034 Query: 2311 GERGFPGYPGPKGNPGEPG---------------------------LNGTTGPKGIRGRR 2343 GE G PG PG G+PG PG G GP+G RG + Sbjct: 1035 GENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDK 1094 Query: 2344 GNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCAL 2379 G +G G G KG G+PG G G+ G + Q A+ Sbjct: 1095 GETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAI 1130 Score = 269 bits (688), Expect = 3e-71 Identities = 164/385 (42%), Positives = 191/385 (49%), Gaps = 57/385 (14%) Query: 2038 GQRGDRGPIGSIGPKGIPG---EDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094 GQ G GP G+ G G PG E G G PG G PG+RG PG G G QG PG G+ Sbjct: 330 GQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGIN 389 Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRG------------DKGPR 2142 GS PG KGE+G G+ G G G +G PG +G G PG RG + GPR Sbjct: 390 GS---PGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPR 446 Query: 2143 GEKGE---------RGDVGIRGDPGNPGQD-----SQERGPKGETGDLGPMGVPGRD--- 2185 GE+GE +G+ G G PG PG + + ERG G G GP G+PG Sbjct: 447 GERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPA 506 Query: 2186 ------------GVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPA 2233 G G PG G GG G RG PG+ G G G+PG G QG G GP Sbjct: 507 GERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPP 566 Query: 2234 GPAGPPGLIGEQGISGPRGSGGAAGAPGER------GRTGPLGRKGEPGEPGPKGGIGNR 2287 GP+GP G G G GP+G+ GA G GER G GP G+ GE G GP G G Sbjct: 567 GPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPG 626 Query: 2288 GPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNS 2346 G +G+TG G G+ G G G GE G PG PGPKG+ G P G G KG G G Sbjct: 627 GDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAP---GAPGGKGDAGAPGER 683 Query: 2347 GPPGIVGQKGDPGYPGPAGPKGNRG 2371 GPPG+ G G G GP GP+G +G Sbjct: 684 GPPGLAGAPGLRGGAGPPGPEGGKG 708 Score = 268 bits (686), Expect = 5e-71 Identities = 170/415 (40%), Positives = 202/415 (48%), Gaps = 77/415 (18%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEG--GP----------GERGPPG---VNGTQ 2082 GQRG+ GP G G +G PG G G PG +G GP G RGPPG NG Sbjct: 366 GQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAP 425 Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVGEIGL------------DGLDGEDGDKGLPGSSGEK 2130 G +G G+ G G++G PG +GE GE G+ DG GE G GLPG++GE+ Sbjct: 426 GLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGER 485 Query: 2131 GNPGRRG---------DKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGV 2181 G PG RG +KGP GE+G G G RG G PG+D GP G G G G Sbjct: 486 GAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGP-GMRGMPGSPGG 544 Query: 2182 PGRDGVPGGPGETGKNG-----------------GF----GRRGPPGAKGNKGGPGQPGF 2220 PG DG PG PG G++G GF G G PG G +GGPG PG Sbjct: 545 PGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGP 604 Query: 2221 EGEQGTRGAQGPAGPAGPPGLIGEQGISGP------RGSGGAAGAPGERGRTGPLGRKGE 2274 +G G G GP GP GP G G++G +GP +G G G PGE G+ G G KG+ Sbjct: 605 QGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGD 664 Query: 2275 PGEPGPKGGIGNRGPRGETGDDG-------RDGVGSEGRRGKKGERGFPGYPGP------ 2321 G PG GG G+ G GE G G R G G G G KG G PG PG Sbjct: 665 AGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGL 724 Query: 2322 KGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQ 2376 +G PGE G G+ GPKG +G G G G+ G+ G G GP GP G G D+ Sbjct: 725 QGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDK 779 Score = 266 bits (680), Expect = 2e-70 Identities = 159/363 (43%), Positives = 183/363 (50%), Gaps = 35/363 (9%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G G GP G GP G PG G+ G PG G G G PG G G G PG G G Sbjct: 168 GLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPA 227 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157 G GE G G G GL G G KG G G G G RG G GEKGE G G++G+ Sbjct: 228 GKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGEN 287 Query: 2158 GNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQ 2217 G PG++ G G +GP G PG G PG PG G G G RG G G G PG Sbjct: 288 GLPGEN-------GAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGT 340 Query: 2218 PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAA---------GAPGERGRTGP 2268 GF G G +G GPAG G G G++G GP+G GA G+PG +G GP Sbjct: 341 AGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGP 400 Query: 2269 LGRKGEP------GEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGP 2321 G G P G PGP G G G RG G+ G++G G G RG++GE G PG PG Sbjct: 401 AGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGA 460 Query: 2322 K------GNPGEPGLNGTTGPKGIRGR---RGNSGPPGIVGQK---GDPGYPGPAGPKGN 2369 K G+PGEPG NG G G RG RG +GP GI G+K G+ G PGPAGP+G Sbjct: 461 KGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGA 520 Query: 2370 RGD 2372 G+ Sbjct: 521 AGE 523 Score = 191 bits (484), Expect = 1e-47 Identities = 118/283 (41%), Positives = 139/283 (49%), Gaps = 41/283 (14%) Query: 2130 KGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDS------------QERGPKGETGDL- 2176 +G G +GD GP G G GD GI G PG+PG Q P+ ++ D+ Sbjct: 102 QGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVK 161 Query: 2177 ------GPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQ 2230 G G PG G PG PG G +G G G PG +G G PGQ G G G GA Sbjct: 162 SGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAI 221 Query: 2231 GPAGPAGP------PGLIGEQGISGPRGSGGAAGAPG---------------ERGRTGPL 2269 GP+GPAG PG GE+G+ GP G G AG PG E+G TG Sbjct: 222 GPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAP 281 Query: 2270 GRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEP 2328 G KGE G PG G G GPRG G+ GR G+ G+ G RG G RG G PGP G PG Sbjct: 282 GLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTA 341 Query: 2329 GLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 G G+ G KG G G+ G G GQ+G+PG G AG +G G Sbjct: 342 GFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPG 384 Score = 169 bits (429), Expect = 3e-41 Identities = 108/280 (38%), Positives = 128/280 (45%), Gaps = 54/280 (19%) Query: 2038 GQRGDRGPIGSIGPKGI------------PGEDGYRGYPGDEGGPGERGPPGVNGTQGFQ 2085 G G +GP G+ GP GI PG G RG PG +G GE G PG NG G + Sbjct: 933 GSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGER 992 Query: 2086 GCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDG---------DKGLPGSSGEKGNPGRR 2136 G PG +G+ G G GE G G G DGL G DG + G PG+ G G+PG Sbjct: 993 GPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPP 1052 Query: 2137 GDKGPRGEKGERGDVGIRGDPGNPGQDSQE--------RGPKGETGDLGPMGV------P 2182 G GP G+ G+RG+ G G G PG RG KGETG+ G G+ P Sbjct: 1053 GPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFP 1112 Query: 2183 GRDGVPGGPGETGKNGGFGR------------RGPPGAKGNKGGPGQ---PGFEGEQGTR 2227 G G PG PG G+ G G GPPG G G PG PG G +G R Sbjct: 1113 GNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGER 1172 Query: 2228 GAQGPAGPAGPPGLIGEQGISGP----RGSGGAAGAPGER 2263 G++G G G PG G G GP G+ AG GE+ Sbjct: 1173 GSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEK 1212 Score = 144 bits (364), Expect = 1e-33 Identities = 93/245 (37%), Positives = 100/245 (40%), Gaps = 42/245 (17%) Query: 2169 PKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQ---- 2224 P GE + P P G G G G G G PG G+ G PGQPG G Sbjct: 80 PFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPG 139 Query: 2225 ----------------------------GTRGAQGPAGPAGPPGLIGEQGISGPRGSGGA 2256 G G GPAGP GPPG G G G GS G Sbjct: 140 ICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGY 199 Query: 2257 AGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV----------GSEGR 2306 G PGE G+ GP G G PG GP G G G G G G G+ G G Sbjct: 200 QGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGF 259 Query: 2307 RGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGP 2366 G KG RGF G G KG G PGL G G G G G GP G G++G PG PG AG Sbjct: 260 PGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGA 319 Query: 2367 KGNRG 2371 +GN G Sbjct: 320 RGNDG 324 Score = 120 bits (302), Expect = 2e-26 Identities = 77/175 (44%), Positives = 89/175 (50%), Gaps = 19/175 (10%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPG------DEGGPGERGPPGVNGTQGFQG 2086 P +G+ GDRG G GP G PG G RG PG D+G GERG G+ G +GF Sbjct: 1054 PVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGF-- 1111 Query: 2087 CPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKG 2146 PG G GS G G++G +G G G G G G PG G G+PG G GPRG +G Sbjct: 1112 -PGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRG 1170 Query: 2147 ERGDVGIRGDPGNPGQDSQERGPKGETGDLGP-MGVPGRDGVPGGPGETGKNGGF 2200 ERG G PG+PGQ GP G G GP G G + G GE K GGF Sbjct: 1171 ERGS---EGSPGHPGQP----GPPGPPGAPGPCCGGVGAAAIAGIGGE--KAGGF 1216 Score = 84.7 bits (208), Expect = 1e-15 Identities = 61/163 (37%), Positives = 71/163 (43%), Gaps = 27/163 (16%) Query: 2232 PAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP---LGRKGEPGEPGPKGGIGNRG 2288 P P G + Q + P G G +G GP GR G+PG PG G G+ G Sbjct: 77 PEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPG 136 Query: 2289 PRG-----ETGD----------DGRDGVGSEGRRGKKGERGFPGYPGP---KGNPGEPGL 2330 P G TG D + GV G G G G PG PGP G+PG PG Sbjct: 137 PPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGS 196 Query: 2331 NGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373 G GP G G+ G SGPP G PG GP+GP G G+S Sbjct: 197 PGYQGPPGEPGQAGPSGPP------GPPGAIGPSGPAGKDGES 233 >gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] Length = 1745 Score = 285 bits (729), Expect = 5e-76 Identities = 163/351 (46%), Positives = 187/351 (53%), Gaps = 17/351 (4%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGV------NGTQGFQGCPGQR 2091 G +GD+G G G GI G G+ G PG +G G RGPPG+ +G +GF G G Sbjct: 1088 GSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPP 1147 Query: 2092 GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRG---DKGPRGEKGER 2148 G++G G PGEKGEVG++G G G G +G G +G +G PG G G GEKGER Sbjct: 1148 GLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGER 1207 Query: 2149 GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208 GD G G PG PG +G GE GD GP G G G G PGE G G G G PG Sbjct: 1208 GDAGDPGPPGAPGIPGP-KGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGD 1266 Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2268 G G PG G +G G +G G G GPPG GE G GP G G +G G GR G Sbjct: 1267 LGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGE 1326 Query: 2269 LGRKGEPGEPGPKGG---IGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGN 2324 G KGEPG GP G +G RGP G G +G G+ G G G G G G PGP G Sbjct: 1327 KGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGP 1386 Query: 2325 PGEPGLNGTTGPKGIRGRRGNSG---PPGIVGQKGDPGYPGPAGPKGNRGD 2372 G PGL G TGPKG +G G G PPG G+KGD G PG GP G +GD Sbjct: 1387 SGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGD 1437 Score = 284 bits (726), Expect = 1e-75 Identities = 169/410 (41%), Positives = 202/410 (49%), Gaps = 52/410 (12%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G G++GP G+ G G+PG DG G+PG EG GE+G G G+ G G PG RGVKG+ Sbjct: 659 GTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTS 718 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157 G G +GE GE G DG G GD GL G G+ G PG RG+ GP G KG+ G G G P Sbjct: 719 GNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPP 778 Query: 2158 GNPGQDSQ-----------ERGPKGETGDLGPM------------GVPGRDGVPGGPGET 2194 G+ G+ + GPKG G GP+ G PG +G G PG Sbjct: 779 GSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSR 838 Query: 2195 GKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGP---AGPAGPP------------ 2239 G+ G G G PG KG+ G G PG GE+G G QGP GP GPP Sbjct: 839 GERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHP 898 Query: 2240 ---GLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDD 2296 G +G QG +GP G G G G+ G GPLG +G PG PGP G G G G G Sbjct: 899 GQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAK 958 Query: 2297 GRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPK---------GIRGRRGNSG 2347 G +G G GK+G G G+PGPKG PG+PG G G K G G RG G Sbjct: 959 GE--LGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLG 1016 Query: 2348 PPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCPCCYGPLECP 2397 P G +G G G GP GP G +G ++ + KD P GPL P Sbjct: 1017 PAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPP 1066 Score = 276 bits (707), Expect = 2e-73 Identities = 160/358 (44%), Positives = 190/358 (53%), Gaps = 30/358 (8%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G G +GP G GP G PG G G PG +G G G G G +GF G PG G KG R Sbjct: 506 GAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQR 565 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157 G + G VG+ G G DGE G +G PG +G+ G PG RG GPRG G G G+ G Sbjct: 566 G---DFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGID 622 Query: 2158 GNPGQDSQ-----ERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNK 2212 G PG E GP G+ G+ G G+PG G+ G PGE G G G PG G+ Sbjct: 623 GAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPP---GNPGIPGLPGSD 679 Query: 2213 GGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRK 2272 G G PG EG G +GAQGP G AGPPG G +G+ G G+ G G GE+G G G K Sbjct: 680 GPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFK 739 Query: 2273 GE---------PGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGY---P 2319 G+ PG PGP+G G GP+G+ G G +G GS G +GK G G PGY P Sbjct: 740 GDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRP 799 Query: 2320 GPKGNPGEPGLNGTTGPKGIRGR------RGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 GPKG+ G PG G G KG G+ G GPPG G++G PG G GPKG+ G Sbjct: 800 GPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVG 857 Score = 275 bits (704), Expect = 4e-73 Identities = 164/397 (41%), Positives = 200/397 (50%), Gaps = 44/397 (11%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQG------FQGCPGQR 2091 G+ G +G +G GP G G G RG+PG +GGPG+ GP G+ G +G G PG+R Sbjct: 953 GREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGER 1012 Query: 2092 GVKGSRG---FPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER 2148 G G G PG+ G G +G G G G++G PG +G+ G PG G GP G G Sbjct: 1013 GPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPS 1072 Query: 2149 GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208 G+ G +GD G PG +G KG+ GD GP G PG G G PG G +G GRRGPPG Sbjct: 1073 GEEGDKGDVGAPGH----KGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGL 1128 Query: 2209 KGNKGG------------------PGQPGFEGE------QGTRGAQGPAGPAGPPGLIGE 2244 G KG PG PG +GE G GA GP GP GP G G Sbjct: 1129 FGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGT 1188 Query: 2245 QGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRG---PRGETGDDGRDGV 2301 G+ G G GA G GERG G G G PG PGPKG IG +G P G G G+ G Sbjct: 1189 PGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGP 1248 Query: 2302 -GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKG---D 2357 G +G +G G G PG GP G+PG G++G+ G KG G G GPPG G+ G Sbjct: 1249 PGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGP 1308 Query: 2358 PGYPGPAGPKGNRGDSIDQCALIQSIKDKCPCCYGPL 2394 PG GP+G G G ++ A + D P GP+ Sbjct: 1309 PGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPM 1345 Score = 275 bits (704), Expect = 4e-73 Identities = 158/345 (45%), Positives = 182/345 (52%), Gaps = 14/345 (4%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096 +G+ G GP+G +GP G G G G GD G PG +G G G G G PG RG G Sbjct: 1051 TGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGH 1110 Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGD 2156 G PG G G G GL G+ GD G+ G G G PG +G GP GEKGE GDVG G Sbjct: 1111 PGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGP 1170 Query: 2157 PGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPG 2216 G PG RGP+G TG G G+PG G PG GE G+ G G GPPGA G G G Sbjct: 1171 HGAPGP----RGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKG 1226 Query: 2217 QPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPG 2276 G +G+ G GA GP G GPPG G +G GP G G G PG+ G +G G GE G Sbjct: 1227 DIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKG 1286 Query: 2277 EPGPKGGIGNRGPRGETGDDGRDGV----GSEGRRGKKGERGFPGYPGPKGNPGEPGLNG 2332 +PG GG G G GE G G G G GR G++GE+G G PGP G PG G G Sbjct: 1287 DPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMG 1346 Query: 2333 T------TGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 GP+G+RG G G PG++G G G PGP GP G G Sbjct: 1347 ARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPG 1391 Score = 273 bits (697), Expect = 3e-72 Identities = 171/400 (42%), Positives = 205/400 (51%), Gaps = 68/400 (17%) Query: 2037 SGQRGDRGPIGSIGPKG---IPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGV 2093 +GQ G+ GP GS G KG +PG GY G PG +G G GP G G +G G GQ G+ Sbjct: 769 AGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGL 828 Query: 2094 KGSRGFPGEKGEVGEIGLDGLDGEDGD---KGLPGSSGEKGNPGRR------GDKGPRGE 2144 +G RG PG +GE G+ G G G GD G PG GEKG PG + G KGP G Sbjct: 829 EGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGH 888 Query: 2145 K---------GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETG 2195 + G+RG++G +G G PG + GP+G+TG++GP+G G G PG PGE G Sbjct: 889 QGKDGRPGHPGQRGELGFQGQTGPPG-PAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQG 947 Query: 2196 KNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGG 2255 G GR GAKG G PG G EG G RG GP G G PG G +G GP G G Sbjct: 948 LPGLEGRE---GAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVG 1004 Query: 2256 AAGAPGERGRTGPLGRKGEPGEP------GPKGGIGNRGPRGETGDDGRDGV-------- 2301 A G+PGERG GP G G PG+ GP G G+RG RG G G+DG+ Sbjct: 1005 ANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLG 1064 Query: 2302 -----GSEGRRGKKGERGFPGYPGPKGN------PGEPGLNGTT---GPKGIRGRRGNSG 2347 G G G KG+ G PG+ G KG+ PG+PG+ G GP G G +G G Sbjct: 1065 PPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRG 1124 Query: 2348 PPGIVGQKGD---------------PGYPGPAGPKGNRGD 2372 PPG+ GQKGD G PGP G KG GD Sbjct: 1125 PPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGD 1164 Score = 271 bits (694), Expect = 6e-72 Identities = 165/368 (44%), Positives = 187/368 (50%), Gaps = 33/368 (8%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPG---QRGVK 2094 GQRG+ G G GP G G G +G G+ G GERGPPG G G QG PG + G K Sbjct: 899 GQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAK 958 Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154 G G PG G+ G GL G G G G PG +G KG+ G G G G GERG +G Sbjct: 959 GELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPA 1018 Query: 2155 GDPGNPGQDSQE-----RGPKGETGDLGPMGVPGRDGVPGG------PGETGKNGGFGRR 2203 G G PGQ E G KG G+ GP G G+DG+PG PG G +G G + Sbjct: 1019 GGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDK 1078 Query: 2204 GPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGP------------R 2251 G GA G+KG G G G G G +GPAG GPPG G QG GP R Sbjct: 1079 GDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVR 1138 Query: 2252 GSGGAAGAPGERGRTGPLGRKGEPGE---PGPKGGIGNRGPRGETGDDGR----DGVGSE 2304 G G G PG +G GP G KGE G+ GP G G RGP+G TG +G GVG Sbjct: 1139 GFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQP 1198 Query: 2305 GRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPA 2364 G G+KGERG G PGP G PG PG G G KG G G +GPPG G G+ G G Sbjct: 1199 GAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSV 1258 Query: 2365 GPKGNRGD 2372 GP G GD Sbjct: 1259 GPTGLPGD 1266 Score = 271 bits (693), Expect = 8e-72 Identities = 154/359 (42%), Positives = 186/359 (51%), Gaps = 24/359 (6%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096 +G +GD+GP G +G G PGE G G G G PG+ G G G G +G G+RG G Sbjct: 991 TGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGP 1050 Query: 2097 RG---FPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI 2153 G PG G +G G G GE+GDKG G+ G KG+ G +GD GP G+ G RG G Sbjct: 1051 TGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGH 1110 Query: 2154 RGDPGNPGQDSQ--------ERGPKGETGDLGPMGVPGRDGVPGGPGETGK--------- 2196 G PG G + ++G G G +G +G PG G+PG PGE G+ Sbjct: 1111 PGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGP 1170 Query: 2197 NGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGA 2256 +G G RGP G G++G PG PG G+ G G +G G AG PG G GI GP+G G Sbjct: 1171 HGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGE 1230 Query: 2257 AGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV----GSEGRRGKKGE 2312 G G G GP G+KG PGE G KG +G G G+ G G GV GS G +G G+ Sbjct: 1231 KGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGD 1290 Query: 2313 RGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 G PG PG G PG PG G GP G GR G G G G+ G G PG GP G RG Sbjct: 1291 VGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARG 1349 Score = 270 bits (691), Expect = 1e-71 Identities = 169/410 (41%), Positives = 198/410 (48%), Gaps = 78/410 (19%) Query: 2037 SGQRGDRGPIGSIGPKGIPGE---------DGYRGYPGDEGGPGERGPPGVNGTQGFQGC 2087 +GQ G+ GP G +GP+G PG DG G G+ G PGE GPPG G G QG Sbjct: 592 TGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGL 651 Query: 2088 PGQRGVKGSRGFPGEKGEVGEIGLDGLDGED------------------------GDKGL 2123 PG +G+ G+ PGEKG G G+ GL G D G G Sbjct: 652 PGPQGLIGT---PGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGY 708 Query: 2124 PGSSGEKGNPGRRGDKGPRGEKGE------RGDVGIRGDPGNPGQ--------------- 2162 PG G KG G RG +G +GEKGE +GDVG++GD G PG Sbjct: 709 PGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQ 768 Query: 2163 --DSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGF 2220 + E GP G G+ G +GVPG G PG PG G G G GP G KG G GQPG Sbjct: 769 AGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGL 828 Query: 2221 EGE------QGTRGAQGPAGPAGPPGLIGEQ---GISGPRGSGGAAGAPGERGRTGPLGR 2271 EGE +G RG G G GP G +G+ GI G +G G G PG G GP G Sbjct: 829 EGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGH 888 Query: 2272 KGEPGEPGPKGGIGNRGPRGETGDDGRDGV----GSEGRRGKKGERGFPGYPGPKGNPGE 2327 +G+ G PG G G G +G+TG G GV G G G GERG PG PGP G G Sbjct: 889 QGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGL 948 Query: 2328 PGL------NGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 PGL G GP G G+ G +G G G KG PG PGP G KG++G Sbjct: 949 PGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKG 998 Score = 270 bits (690), Expect = 2e-71 Identities = 156/345 (45%), Positives = 184/345 (53%), Gaps = 29/345 (8%) Query: 2040 RGDRGPIGSIG---PKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096 +G GP+G G P G+PG G +G G EG G RG G +G G G G+ G G+ Sbjct: 478 KGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGA 537 Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGD 2156 RG PG+ G G+ G DGL G G+KG G G G PG G+ G RG +G G G G+ Sbjct: 538 RGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGE 597 Query: 2157 PGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPG 2216 PG RG G G GP G PG G+ G PG G G G GPPG +GN G G Sbjct: 598 PG-------PRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQG 650 Query: 2217 QPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPG 2276 PG +G GT G +GP G G PGL G GP G G G GE+G GP G G PG Sbjct: 651 LPGPQGLIGTPGEKGPPGNPGIPGL---PGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPG 707 Query: 2277 EPGP---KGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGLNG 2332 PGP KG GNRG +GE G+ G DG G +G G KG++G PG PGP+G +G Sbjct: 708 YPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGE------DG 761 Query: 2333 TTGPKGIRGRRGNSGPPGIVGQKGD------PGYPGPAGPKGNRG 2371 GPKG G+ G GPPG G+KG PGYPG GPKG+ G Sbjct: 762 PEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIG 806 Score = 267 bits (683), Expect = 1e-70 Identities = 152/354 (42%), Positives = 182/354 (51%), Gaps = 22/354 (6%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQ------- 2090 G GD GP G G G+PG G +G GD G G+ GPPG +G +G +G PG Sbjct: 539 GLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEP 598 Query: 2091 --RGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER 2148 RG+ G RG PG G G G+DG G G+ G PG G G G G +G G +G Sbjct: 599 GPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLI 658 Query: 2149 GDVGIRGDPGNPGQDS--------QERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGF 2200 G G +G PGNPG G +G TG+ G G PG G PG PG G G Sbjct: 659 GTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTS 718 Query: 2201 GRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAP 2260 G RG G KG KG G PGF+G+ G +G QG G GP G G +G G G G G P Sbjct: 719 GNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPP 778 Query: 2261 ---GERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPG 2317 GE+G+ G G G PG PGPKG IG GP G G+ G+ G G+ G +GERG PG Sbjct: 779 GSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKS--GKTGQPGLEGERGPPG 836 Query: 2318 YPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 G +G PG G G G G G G G G+ G +G PG+PGP GP G++G Sbjct: 837 SRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQG 890 Score = 247 bits (631), Expect = 1e-64 Identities = 153/342 (44%), Positives = 179/342 (52%), Gaps = 30/342 (8%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGI------PGEDGYRGYPGDEGGPGERGPPGVNGTQGFQG 2086 P G RG +GP GS G G+ PG G +G GD G PG G PG+ G +G G Sbjct: 1170 PHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIG 1229 Query: 2087 CPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKG 2146 G G G+ G PG+KG GE DG G G GLPG G G+PG G G GEKG Sbjct: 1230 EKGDSGPSGAAGPPGKKGPPGE---DGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKG 1286 Query: 2147 ERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPP 2206 + GDVG G PG G+ GP G+ G G MG GR+G G GE G +G GR GP Sbjct: 1287 DPGDVGGPGPPGASGEPGAP-GPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPM 1345 Query: 2207 GAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRT 2266 GA+ G PG G +G RG GP G PGL+G G GP G G +G PG +G T Sbjct: 1346 GAR------GPPGRVGPEGLRGI---PGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDT 1396 Query: 2267 GPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPG 2326 GP KGE G G G IG G GE GD G GV +G G +G PG PGP G+ G Sbjct: 1397 GP---KGEKGHIGLIGLIGPPGEAGEKGDQGLPGV-----QGPPGPKGDPGPPGPIGSLG 1448 Query: 2327 EPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKG 2368 PG G GP G++G+ G PG +G +GD G GP GP G Sbjct: 1449 HPGPPGVAGP---LGQKGSKGSPGSMGPRGDTGPAGPPGPPG 1487 Score = 244 bits (624), Expect = 8e-64 Identities = 151/362 (41%), Positives = 176/362 (48%), Gaps = 51/362 (14%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPG-------Q 2090 G G GP G +GP G PG G+ PGD G PG G PG+ G G +G PG Q Sbjct: 392 GPPGAPGPQGVVGPSGPPGPPGF---PGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQ 448 Query: 2091 RGVKGSRGFP-----------------GEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNP 2133 +G P KG G +GL G G GLPG G KG Sbjct: 449 FAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTG---RPGPVGLPGHPGLKGEE 505 Query: 2134 GRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGE 2193 G G +GPRG +G G G G G PG D G +G GD GP G G DG+PG PGE Sbjct: 506 GAEGPQGPRGLQGPHGPPGRVGKMGRPGAD----GARGLPGDTGPKGDRGFDGLPGLPGE 561 Query: 2194 TGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGS 2253 G+ G FG GQPG GE G RGA+GP GP G G G +G+ GPRGS Sbjct: 562 KGQRGDFGH------------VGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGS 609 Query: 2254 GGAAGAPGERGRTGPLGRKGE---PGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKK 2310 G G PG G G G KG PGEPGP G GN G +G G G +G+ G +G Sbjct: 610 PGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGL--IGTPGEKGPP 667 Query: 2311 GERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNR 2370 G G PG PG G G PG G TG KG +G G++GPPG G +G G G G +G + Sbjct: 668 GNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEK 727 Query: 2371 GD 2372 G+ Sbjct: 728 GE 729 Score = 186 bits (471), Expect = 4e-46 Identities = 134/350 (38%), Positives = 159/350 (45%), Gaps = 58/350 (16%) Query: 2065 GDEG--GPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPG--EKGEVGEIGLDGLDGEDGD 2120 GD+ GP R + TQ FQ PG G KG++G P EKG+ E G G G Sbjct: 346 GDDSTMGPDFRAAEYPSRTQ-FQIFPGA-GEKGAKGEPAVIEKGQQFE----GPPGAPGP 399 Query: 2121 KGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQ---------DSQERGP-- 2169 +G+ G SG G PG GD GP G G G GI G G PG +GP Sbjct: 400 QGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPV 459 Query: 2170 ------------------KGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGN 2211 KG G +G G PG G+PG PG G+ G G +GP G +G Sbjct: 460 SFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGP 519 Query: 2212 KGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGR 2271 G PG+ G G G GA+G G GP G RG G G PGE+G+ G G Sbjct: 520 HGPPGRVGKMGRPGADGARGLPGDTGP---------KGDRGFDGLPGLPGEKGQRGDFGH 570 Query: 2272 KGEPGEPGPKGGIGNRGPRGETGDDGRDGV-------GSEGRRGKKGERGFPGYPGPKGN 2324 G+PG PG G G GP G TG G G GS G G+ G G G PG KGN Sbjct: 571 VGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGN 630 Query: 2325 PGEPGLNGTTGPKGIRGRRGNSGPPGIV---GQKGDPGYPGPAGPKGNRG 2371 G PG G G +G G +G GP G++ G+KG PG PG G G+ G Sbjct: 631 VGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDG 680 Score = 136 bits (343), Expect = 3e-31 Identities = 89/227 (39%), Positives = 100/227 (44%), Gaps = 39/227 (17%) Query: 2183 GRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLI 2242 G G G P K F GPPGA G +G G G G G G GP GPAG PG+ Sbjct: 373 GEKGAKGEPAVIEKGQQF--EGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIP 430 Query: 2243 GEQGISGPRGS------------------------------------GGAAGAPGERGRT 2266 G GI GP G+ G G G GR Sbjct: 431 GIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRP 490 Query: 2267 GPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNP 2325 GP+G G PG G +G G +GPRG G G G VG GR G G RG PG GPKG+ Sbjct: 491 GPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDR 550 Query: 2326 GEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 G GL G G KG RG G+ G PG G+ G+ G GP GP G G+ Sbjct: 551 GFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGE 597 >gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo sapiens] Length = 1650 Score = 282 bits (721), Expect = 4e-75 Identities = 166/361 (45%), Positives = 191/361 (52%), Gaps = 39/361 (10%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGD------EGGPGERGPPGVNGTQGFQGCPGQR 2091 G RG GP G IG +G+PG G +G GD G PG RGP G NG G QG PG Sbjct: 1058 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG-- 1115 Query: 2092 GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD- 2150 GV G+ G PGEKGE GE G G+ GE G KG G GEKG G+ G+ GP G KG GD Sbjct: 1116 GV-GNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD 1174 Query: 2151 --------VGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGR 2202 VG GDPG PG+ RG G GD G G PG+ G PG GE G G G+ Sbjct: 1175 GPKGNPGPVGFPGDPGPPGEGGP-RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGK 1233 Query: 2203 RGP---PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGA 2259 RGP PG++G +GG G G G G G GP GPAGP G G G+ G GS G G Sbjct: 1234 RGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGR 1293 Query: 2260 PGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYP 2319 PG G+ GP G G PG PG +G G +G +G G G +G G +G+KG+RG PG Sbjct: 1294 PGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL--IGPPGEQGEKGDRGLPGPQ 1351 Query: 2320 GPKGNPGE---------------PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPA 2364 G G GE PGL G GPKG +G G GP G G +G PG+PGP Sbjct: 1352 GSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPP 1411 Query: 2365 G 2365 G Sbjct: 1412 G 1412 Score = 281 bits (719), Expect = 7e-75 Identities = 160/348 (45%), Positives = 190/348 (54%), Gaps = 17/348 (4%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G+ G GP G IGP G PG G G PG G G G G GT+GF G PG G++G Sbjct: 1016 GEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLP 1075 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPG---SSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154 G GEKGE G++G G G G +G G + G +G PG G+ GP GEKGE G+ G Sbjct: 1076 GPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSP 1135 Query: 2155 GDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGG 2214 G G PG +GP+GE G+ G G PG G PG G TG +G G GP G G+ G Sbjct: 1136 GIQGEPGV----KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGP 1191 Query: 2215 PGQPGFEGEQGT---RGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGR 2271 PG+ G G+ G RG G G G PG GE G GP G G AG+PG GR G G Sbjct: 1192 PGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGA 1251 Query: 2272 KGEPGE---PGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGE 2327 KG+PG PG G +G GP G+ G DG G+ GS G++G+ G G G PGP G PG Sbjct: 1252 KGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGL 1311 Query: 2328 PGLNGTTGPKGIRGRRGNSG---PPGIVGQKGDPGYPGPAGPKGNRGD 2372 PGL G G KG +G G G PPG G+KGD G PGP G G +G+ Sbjct: 1312 PGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGE 1359 Score = 281 bits (718), Expect = 9e-75 Identities = 173/398 (43%), Positives = 198/398 (49%), Gaps = 65/398 (16%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERG---------------PPGVNGTQ 2082 G G++GP G G G+PG DG G+PG EG PG +G P GV G Sbjct: 581 GPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVD 640 Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVG------EIGLDGLDGEDG------------DKGLP 2124 G +G G +G KG GFPG KG++G E+G+ G GEDG D G P Sbjct: 641 GIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPP 700 Query: 2125 GSSGEKGN---------PGRRGDKGP---------RGEKGER---GDVGIRGDPGNPGQD 2163 G GEKG PGR+G KG GEKG R G G RG+ G G Sbjct: 701 GLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPR 760 Query: 2164 SQERGPKGETGDLGPMGVPGRDGVPGGPGE------TGKNGGFGRRGPPGAKGNKGGPGQ 2217 Q RGP+G TG G G G DG G PGE G NG G +GPPG G G PG Sbjct: 761 GQ-RGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGH 819 Query: 2218 PGFEGEQGTRGAQGPAGP---AGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGE 2274 PG GE G +G GP GP GP G GE G G RG G G PGE+G G G++G Sbjct: 820 PGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 879 Query: 2275 PGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGT 2333 G+PGP G G GP G G G G+ G+ G G KG G G PGP G+PGE G G+ Sbjct: 880 KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 939 Query: 2334 TGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 GP G GR G GPPG G+KG PG GP GP G G Sbjct: 940 GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDG 977 Score = 279 bits (714), Expect = 3e-74 Identities = 161/349 (46%), Positives = 193/349 (55%), Gaps = 21/349 (6%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERG---PPGVNGTQGFQGCPGQRGVK 2094 G G +GP GS+GP+G PG G +G PG +G PG +G P G G QG G PG G Sbjct: 542 GMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSD 601 Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGE------R 2148 G G PG++G G G G G G G PG G KG G RG KG +GEKGE + Sbjct: 602 GPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFK 661 Query: 2149 GDVGIRGD------PGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGR 2202 GD+G++GD PG+ G+D E GPKG TG G G PG G G G G G GR Sbjct: 662 GDIGVKGDRGEVGVPGSRGEDGPE-GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR 720 Query: 2203 RGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE 2262 +GP KG+ G PG PG GE+G RG G +GP G G G +G GPRG+ G +GA G Sbjct: 721 QGP---KGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGT 777 Query: 2263 RGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPK 2322 G GP G GE G PGP+G G GP+G G G+DG+ G G++GE GF G GP Sbjct: 778 SGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL--PGHPGQRGEVGFQGKTGPP 835 Query: 2323 GNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 G PG G G G G G RG+ GPPG G++G PG G G KG+ G Sbjct: 836 GPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPG 884 Score = 278 bits (712), Expect = 5e-74 Identities = 162/365 (44%), Positives = 185/365 (50%), Gaps = 26/365 (7%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGV---NGTQGFQGCPG 2089 P +G+ G G G GP G PGE G G G EG G+ GPPG +G G +G PG Sbjct: 843 PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG 902 Query: 2090 QRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERG 2149 +RG+ G+ G PG KG G G G G G++G GS G G PGR G +GP G GE+G Sbjct: 903 ERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKG 962 Query: 2150 DVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPG---GPGETGKNGGFGRRGPP 2206 G +G G G+D + GP G G GP GV G DG G PG+ G G G GPP Sbjct: 963 VPGEKGPIGPTGRDGVQ-GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPP 1021 Query: 2207 GAKGNKGGPGQPGFEGEQGTRGAQGPAGPAG------------PPGLIGEQGISGPRGSG 2254 G G G GQPG G G GA+GP G G PPG IG QG+ GP G Sbjct: 1022 GPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEK 1081 Query: 2255 GAAG------APGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRR 2307 G G PG G GP G G G GP GG+GN GP GE G+ G G G +G Sbjct: 1082 GETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEP 1141 Query: 2308 GKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPK 2367 G KG RG G G G PGEPG G GP G G +GN GP G G G PG GP G Sbjct: 1142 GVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQD 1201 Query: 2368 GNRGD 2372 G +GD Sbjct: 1202 GAKGD 1206 Score = 278 bits (710), Expect = 8e-74 Identities = 161/357 (45%), Positives = 188/357 (52%), Gaps = 27/357 (7%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGV--- 2093 SG++G RG G GP+G G G RG G G G+ G G +G G G PG+RG+ Sbjct: 736 SGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGP 795 Query: 2094 KGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI 2153 +G GFPG KG G G DGL G G +G G G+ G PG G GP+G GE G +G Sbjct: 796 QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 855 Query: 2154 RGDPGNPGQDSQE-----RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208 RG PG PG ++ G +G GD GP G PG+DG G G G+ G G G PG Sbjct: 856 RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGL 915 Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2268 KGN+G G PG G G RGA G GP GPPG G Q GP G+ G G PGE+G GP Sbjct: 916 KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQ---GPPGAAGEKGVPGEKGPIGP 972 Query: 2269 LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGE 2327 GR G G G G G G GE GD G G G +G +G KGE G PG PGP G G+ Sbjct: 973 TGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQ 1032 Query: 2328 PGLNGTTGPKGIR------------GRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 PG G G G R G RG +GPPG +G + G PGP+G KG GD Sbjct: 1033 PGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ---GLPGPSGEKGETGD 1086 Score = 272 bits (695), Expect = 4e-72 Identities = 154/344 (44%), Positives = 188/344 (54%), Gaps = 30/344 (8%) Query: 2043 RGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGE 2102 RGP G +G G PG G G PG +G G+ GP G G QG G PG+ G +G G G Sbjct: 400 RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 459 Query: 2103 KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQ 2162 +G G+ G+ G G DG GLPG G +G+ G +G GP GE GERGD G Sbjct: 460 RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDG---------- 509 Query: 2163 DSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEG 2222 E GP+G G+ GP G+ G G PG PG G G G +GP G+ G +G PG PG +G Sbjct: 510 ---EIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQG 566 Query: 2223 EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKG 2282 GT+G GP G GP G G QG G G G+ G PG G+ GP G KG G GP+G Sbjct: 567 TPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQG 626 Query: 2283 GIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYP---------GPKGNPGEPGLNGT 2333 +G GPRG G DG G+ +G +G+KGE GFPG+ G G PG G +G Sbjct: 627 PLGYPGPRGVKGVDGIRGL--KGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGP 684 Query: 2334 TGPKGIRGRRGNSGPPGIVGQKGD------PGYPGPAGPKGNRG 2371 GPKG G G+ GPPG++G+KG PGYPG GPKG+ G Sbjct: 685 EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLG 728 Score = 270 bits (690), Expect = 2e-71 Identities = 157/393 (39%), Positives = 198/393 (50%), Gaps = 57/393 (14%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDG---YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094 G G G G GP G PG+DG RG+PG+ G PG G PG+ G +G G PG G Sbjct: 872 GTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 931 Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI- 2153 G RG G G +G G G +G PG++GEKG PG +G GP G G +G VG+ Sbjct: 932 GERGAAGSGGPIGP------PGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLP 985 Query: 2154 --------------RGDPGNPGQ-----DSQERGPKGETGDLGPMGVPGRDGVPGGPGET 2194 +G+ G+PGQ + E GP G G +GP+G PG G G PG Sbjct: 986 GPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGAR 1045 Query: 2195 GKNGGFGRRGPPGAKGNKGGPGQPGFEG---EQGTRGAQGPAGPAGPPGLIGEQGISGPR 2251 G G FG +G G +G G PG G +G G +G G GP GPPG G +G +GP Sbjct: 1046 GPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPN 1105 Query: 2252 GSGGAAGAPGERGRTGPLGRKGEPGE---PGPKGGIGNRGPRGETGDDGRDGV----GSE 2304 G+ G G PG G GP G KGEPGE PG +G G +GPRGE G+ G G G Sbjct: 1106 GADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1165 Query: 2305 GRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGN------------------S 2346 G +G G+ G G PGP G PG+PG G GP+G G +G+ + Sbjct: 1166 GPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGEN 1225 Query: 2347 GPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCAL 2379 GPPG +G++G G PG G +G +G D A+ Sbjct: 1226 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAI 1258 Score = 270 bits (689), Expect = 2e-71 Identities = 164/375 (43%), Positives = 189/375 (50%), Gaps = 44/375 (11%) Query: 2040 RGDRGPIGSIG---PKGIPGEDGYRGYPGDEGGPGERGPPGVNG------------TQGF 2084 RG GP+G G P G PG G +G GD G G RGP G+ G G Sbjct: 400 RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 459 Query: 2085 QGCPGQRGVKGSRGF------PGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGD 2138 +G PG GVKG RGF PGEKG G+ G GL G G+ G G GE G G G+ Sbjct: 460 RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 519 Query: 2139 KGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGG---PGETG 2195 GPRG G +G GI G PG G D + GPKG G G G PG+ G PG PG G Sbjct: 520 SGPRGLLGPKGPPGIPGPPGVRGMDGPQ-GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQG 578 Query: 2196 KNGGFGRRGP------PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGP---------PG 2240 G G +GP PG G+ G PG PG EG GT+G QGP+GP GP G Sbjct: 579 AIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKG 638 Query: 2241 LIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG 2300 + G +G+ G +G G G PG +G G G +GE G PG +G G GP+G TG G G Sbjct: 639 VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG 698 Query: 2301 V-GSEGRRGKKGERGFPGYP---GPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKG 2356 G G +GK G G PGYP GPKG+ G PG G +G KG RG G SGP G G G Sbjct: 699 PPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTG 758 Query: 2357 DPGYPGPAGPKGNRG 2371 G GP G G G Sbjct: 759 PRGQRGPRGATGKSG 773 Score = 269 bits (688), Expect = 3e-71 Identities = 162/381 (42%), Positives = 192/381 (50%), Gaps = 40/381 (10%) Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGG------PGERGPPGV---NGT 2081 G P G+ G +GP G+ G KG+PGE G G G +G PG GPPGV +G Sbjct: 940 GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGD 999 Query: 2082 QGFQGCPGQRGVKGSRGF------PGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGR 2135 +G G PGQ+G KG++G PG G VG+ G G DGE G +G G G KG+ G Sbjct: 1000 KGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGT 1059 Query: 2136 RGDKGP------------RGEKGERGDVGIRGDPGNPGQ-----DSQERGPKGETGDLGP 2178 RG GP GEKGE GDVG G PG PG + GP+G G +G Sbjct: 1060 RGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN 1119 Query: 2179 MGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGP 2238 +G PG G PG G G G G +GP G +G KG GQPG G G +G G GP G Sbjct: 1120 LGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN 1179 Query: 2239 PGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGG------IGNRGPRGE 2292 PG +G G GP G GG G G +G G G G+PG PGP G +G RGP G Sbjct: 1180 PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1239 Query: 2293 TGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIV 2352 G +GR G +G +G G G PG GP G G G G G +G+ G G G PG Sbjct: 1240 PGSEGRQG--GKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGAT 1297 Query: 2353 GQKGDPGYPGPAGPKGNRGDS 2373 GQ G PG GP G G RGD+ Sbjct: 1298 GQAGPPGPVGPPGLPGLRGDA 1318 Score = 266 bits (681), Expect = 2e-70 Identities = 160/377 (42%), Positives = 195/377 (51%), Gaps = 50/377 (13%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G+ G+RG G IGP+G+PGE G RG G +G PG GPPGV G G QG G G +G Sbjct: 500 GEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEP 559 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157 G PG++G G GL G G G G G G+ G PG G GP G G+ G G +G+ Sbjct: 560 GPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQ 619 Query: 2158 GNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQ 2217 G G +GP G G G GV G G+ G GE G++G G +G G KG++G G Sbjct: 620 GPSGP----QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV 675 Query: 2218 PGFEGE---QGTRGAQGPAGPAGPPGLIGEQGI------------SGPRGSGGAAGAPG- 2261 PG GE +G +G GP G GPPGL+GE+G GP+GS G G PG Sbjct: 676 PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGA 735 Query: 2262 --ERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPG- 2317 E+G G G+ G GE GP G G RGPRG TG G G G +G G GERG PG Sbjct: 736 SGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGP 795 Query: 2318 -----YPGPKGN---------PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK-------- 2355 +PGPKG PG PG G G +G+ G GPPG+VG + Sbjct: 796 QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEV---GFQGKTGPPGPPGVVGPQGAAGETGP 852 Query: 2356 -GDPGYPGPAGPKGNRG 2371 G+ G+PGP GP G +G Sbjct: 853 MGERGHPGPPGPPGEQG 869 Score = 263 bits (673), Expect = 2e-69 Identities = 160/395 (40%), Positives = 195/395 (49%), Gaps = 57/395 (14%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQR- 2091 P +G+ G +G G GP G PGE G G G G PG +GPPG G G G PGQR Sbjct: 765 PRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRG 824 Query: 2092 --------------GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRG 2137 GV G +G GE G +GE G G G G++GLPG++G++G +G Sbjct: 825 EVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT---KG 881 Query: 2138 DKGPRGEKGERGDVGIRGDPGNPGQDSQERGP-----KGETGDLGPMGVPGRDGVPGGPG 2192 D GP G G+ G G+RG PG G GP +G +G GP G PG G G G Sbjct: 882 DPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGG 941 Query: 2193 ETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPA---GPAGPPGLIGEQGISG 2249 G G G +GPPGA G KG PG+ G G G G QGP GPAGPPG+ GE G G Sbjct: 942 PIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 1001 Query: 2250 PRGSGGAAGAPGERGR------TGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG--- 2300 G G G G +G GP+G G+PG G G G RGP+G G G +G Sbjct: 1002 EVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRG 1061 Query: 2301 -------VGSEGRRGKKGERGFPGYPGPKGNPGEP------GLNGTTGPKGIRGRRGNSG 2347 +G +G G GE+G G GP G PG P G NG GP+G G GN G Sbjct: 1062 FNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLG 1121 Query: 2348 PPGIVGQ---------KGDPGYPGPAGPKGNRGDS 2373 PPG G+ +G+PG GP G +G +G+S Sbjct: 1122 PPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGES 1156 Score = 241 bits (616), Expect = 6e-63 Identities = 148/362 (40%), Positives = 178/362 (49%), Gaps = 35/362 (9%) Query: 2044 GPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK-------GS 2096 GP G GP G+ G G +G PG G PGERGPPG G G G PG G GS Sbjct: 313 GPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGS 372 Query: 2097 RGFPGEKGEV--------------GEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142 G G+KG V + L G G G G PG G+ G+PG +G+ G Sbjct: 373 GG--GDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 430 Query: 2143 GEKGERGDVGIRGDPGNPGQDSQER--GPKGETGDLGPMGVPGRDGVPGGPGETGKNGGF 2200 G +G RG G+ G PG G+ + G +G GD G G G DG+PG PGE G G Sbjct: 431 GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDT 490 Query: 2201 GRRG---PPGAKGNKGGPGQ---PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSG 2254 G +G PPG G +G G+ G GE G RG GP GP G PG G +G+ GP+G Sbjct: 491 GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPK 550 Query: 2255 GAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV----GSEGRRGKK 2310 G+ G GE G G G G G PGP+G IG G +G G G G+ G G GK+ Sbjct: 551 GSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKE 610 Query: 2311 GERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNR 2370 G G G GP G G G G G KG+ G RG G G G+ G PG+ G G KG+R Sbjct: 611 GPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDR 670 Query: 2371 GD 2372 G+ Sbjct: 671 GE 672 Score = 223 bits (569), Expect = 2e-57 Identities = 139/347 (40%), Positives = 172/347 (49%), Gaps = 43/347 (12%) Query: 2050 GPKGIPGEDG----------YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGF 2099 GP+G+ GE G G PG EG G GPPG+ G G G PG+RG G G Sbjct: 291 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 350 Query: 2100 PGEKGEVGEIGLDGL-----DGEDGDKGLPGSSGEKG-----NPGRRGDKGPRGEKGERG 2149 PG G G G + GDKG ++ E R +GP G G G Sbjct: 351 PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTG 410 Query: 2150 DVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAK 2209 G G PG+PG KGE+GDLGP G G G+ G PG+ G RRG GA Sbjct: 411 RPGPLGQPGSPGL-------KGESGDLGPQGPRGPQGLTGPPGKAG------RRGRAGAD 457 Query: 2210 GNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPL 2269 G +G PG PG +G++G G G G G G G QG+ GP G G ERG G + Sbjct: 458 GARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDG------ERGDDGEI 511 Query: 2270 GRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGE- 2327 G +G PGE GP+G +G +GP G G G G+ G +G +G G +G PG PG +G PG Sbjct: 512 GPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQ 571 Query: 2328 --PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 PG G GP G +G +G G PG+ G G PG+PG GP G +G+ Sbjct: 572 GLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN 618 Score = 189 bits (479), Expect = 5e-47 Identities = 114/263 (43%), Positives = 133/263 (50%), Gaps = 26/263 (9%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G+ G G G GPKG G+DG +G PG G PG+ GPPG G +G G G RG G Sbjct: 1154 GESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEP 1213 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKG------------PRGEK 2145 G PG G GE G G G+ G G PGS G +G G +GD G P G Sbjct: 1214 GQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA 1273 Query: 2146 GERGDVGIRGDPGNPGQDSQE--RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRR 2203 G+ G G+RG PG+ GQ + G G G +GP G+PG G G GE G G G Sbjct: 1274 GKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLI 1333 Query: 2204 GPPGAKGNKG-----GP-GQPGFEGEQGTRGAQGP---AGPAGPPGLIGEQGISGPRGSG 2254 GPPG +G KG GP G PG +GE G GA GP GP PGL G G G +G+ Sbjct: 1334 GPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP---PGLPGPAGPKGAKGAT 1390 Query: 2255 GAAGAPGERGRTGPLGRKGEPGE 2277 G G GE+G GP G G PGE Sbjct: 1391 GPGGPKGEKGVQGPPGHPGPPGE 1413 Score = 171 bits (432), Expect = 1e-41 Identities = 101/228 (44%), Positives = 118/228 (51%), Gaps = 10/228 (4%) Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQ 2090 G P G +GDRG G G G PG G G PG G+RGP G G++G QG G Sbjct: 1195 GGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP---LGKRGPAGSPGSEGRQGGKGA 1251 Query: 2091 RGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD 2150 +G G+ G PG+ G VG G G G DG +GLPGS G++G PG G GP G G G Sbjct: 1252 KGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGL 1311 Query: 2151 VGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKG 2210 G+RGD G G E+G G G +GP G G G G PG G G G G PGA G Sbjct: 1312 PGLRGDAGAKG----EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASG 1367 Query: 2211 NKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAG 2258 G G PG G G +GA+G GP GP GE+G+ GP G G G Sbjct: 1368 PIGPGGPPGLPGPAGPKGAKGATGPGGPK---GEKGVQGPPGHPGPPG 1412 Score = 148 bits (373), Expect = 1e-34 Identities = 97/241 (40%), Positives = 121/241 (50%), Gaps = 18/241 (7%) Query: 2140 GPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGG 2199 GPRG KGE+G+ + +PG GP G G G +G PG G PG G+ G+ G Sbjct: 291 GPRGLKGEKGEPAVL-EPG-----MLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGP 344 Query: 2200 FGRRGPPGAKGNKGGPGQP-----GFEGEQGTRGAQGPAGPAGPPGLIGEQGIS--GPRG 2252 GR G PG+ G G PG F G +G A A ++ + ++ GP G Sbjct: 345 PGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPG 404 Query: 2253 SGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGE 2312 G G PG G+ G G KGE G+ GP+G RGP+G TG G+ G GR G G Sbjct: 405 PMGYTGRPGPLGQPGSPGLKGESGDLGPQGP---RGPQGLTGPPGK--AGRRGRAGADGA 459 Query: 2313 RGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 RG PG PG KG+ G GL G G KG RG G G PG G+ G+ G G GP+G G+ Sbjct: 460 RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 519 Query: 2373 S 2373 S Sbjct: 520 S 520 Score = 108 bits (271), Expect = 6e-23 Identities = 67/164 (40%), Positives = 80/164 (48%), Gaps = 9/164 (5%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGT---QGFQGCPGQRGVK 2094 GQ+G G G GP G G G G GD G GE+G PG+ G G QG G RG+ Sbjct: 1289 GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1348 Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154 G +G PG+KGE+G G G G G GLPG +G KG G G GP+GEKG +G G Sbjct: 1349 GPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHP 1408 Query: 2155 GDPGNPGQDSQERGPKGETGDLGPMGVPGRD------GVPGGPG 2192 G PG Q + PK + + D G PG PG Sbjct: 1409 GPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1452 Score = 75.9 bits (185), Expect = 6e-13 Identities = 61/190 (32%), Positives = 69/190 (36%), Gaps = 78/190 (41%) Query: 2260 PGERGRTGPLGRKGEPGE-------------------------------PGPKGGIGNRG 2288 P E GP G KGE GE PGP G G RG Sbjct: 284 PLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 343 Query: 2289 PRGETGDDGRDGV--------------GSEG------------------------RRGKK 2310 P G G G DG GS G RG Sbjct: 344 PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPP 403 Query: 2311 GERGFPGYPGPKGNPGEPGLNGTT---GPKGIRGRRGNSGPPGIVGQKGDP------GYP 2361 G G+ G PGP G PG PGL G + GP+G RG +G +GPPG G++G G P Sbjct: 404 GPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMP 463 Query: 2362 GPAGPKGNRG 2371 G G KG+RG Sbjct: 464 GDPGVKGDRG 473 Score = 54.3 bits (129), Expect = 2e-06 Identities = 32/76 (42%), Positives = 37/76 (48%), Gaps = 4/76 (5%) Query: 2303 SEGRRGKKGERGFPGYPGP----KGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDP 2358 + G RG KGE+G P P +G PG G G GP GI+G G G PG G G Sbjct: 289 AHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA 348 Query: 2359 GYPGPAGPKGNRGDSI 2374 G PG G G G S+ Sbjct: 349 GLPGSDGAPGPPGTSL 364 Score = 39.3 bits (90), Expect = 0.063 Identities = 41/124 (33%), Positives = 48/124 (38%), Gaps = 31/124 (25%) Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQ 2090 G P G G +G G+ GP G GE G +G PG G PGE Q P Q Sbjct: 1372 GGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGE----------VIQPLPIQ 1421 Query: 2091 ------RGVKGSR-----------GFPGEKGEVGEI--GLDGLDGEDGDKGLPGSSGEKG 2131 R V GSR G PG G + EI LD L E P +G + Sbjct: 1422 MPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRP--TGTQD 1479 Query: 2132 NPGR 2135 +P R Sbjct: 1480 SPAR 1483 >gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo sapiens] Length = 1629 Score = 282 bits (721), Expect = 4e-75 Identities = 166/361 (45%), Positives = 191/361 (52%), Gaps = 39/361 (10%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGD------EGGPGERGPPGVNGTQGFQGCPGQR 2091 G RG GP G IG +G+PG G +G GD G PG RGP G NG G QG PG Sbjct: 1037 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG-- 1094 Query: 2092 GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD- 2150 GV G+ G PGEKGE GE G G+ GE G KG G GEKG G+ G+ GP G KG GD Sbjct: 1095 GV-GNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD 1153 Query: 2151 --------VGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGR 2202 VG GDPG PG+ RG G GD G G PG+ G PG GE G G G+ Sbjct: 1154 GPKGNPGPVGFPGDPGPPGEGGP-RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGK 1212 Query: 2203 RGP---PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGA 2259 RGP PG++G +GG G G G G G GP GPAGP G G G+ G GS G G Sbjct: 1213 RGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGR 1272 Query: 2260 PGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYP 2319 PG G+ GP G G PG PG +G G +G +G G G +G G +G+KG+RG PG Sbjct: 1273 PGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL--IGPPGEQGEKGDRGLPGPQ 1330 Query: 2320 GPKGNPGE---------------PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPA 2364 G G GE PGL G GPKG +G G GP G G +G PG+PGP Sbjct: 1331 GSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPP 1390 Query: 2365 G 2365 G Sbjct: 1391 G 1391 Score = 281 bits (719), Expect = 7e-75 Identities = 160/348 (45%), Positives = 190/348 (54%), Gaps = 17/348 (4%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G+ G GP G IGP G PG G G PG G G G G GT+GF G PG G++G Sbjct: 995 GEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLP 1054 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPG---SSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154 G GEKGE G++G G G G +G G + G +G PG G+ GP GEKGE G+ G Sbjct: 1055 GPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSP 1114 Query: 2155 GDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGG 2214 G G PG +GP+GE G+ G G PG G PG G TG +G G GP G G+ G Sbjct: 1115 GIQGEPGV----KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGP 1170 Query: 2215 PGQPGFEGEQGT---RGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGR 2271 PG+ G G+ G RG G G G PG GE G GP G G AG+PG GR G G Sbjct: 1171 PGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGA 1230 Query: 2272 KGEPGE---PGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGE 2327 KG+PG PG G +G GP G+ G DG G+ GS G++G+ G G G PGP G PG Sbjct: 1231 KGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGL 1290 Query: 2328 PGLNGTTGPKGIRGRRGNSG---PPGIVGQKGDPGYPGPAGPKGNRGD 2372 PGL G G KG +G G G PPG G+KGD G PGP G G +G+ Sbjct: 1291 PGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGE 1338 Score = 281 bits (718), Expect = 9e-75 Identities = 173/398 (43%), Positives = 198/398 (49%), Gaps = 65/398 (16%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERG---------------PPGVNGTQ 2082 G G++GP G G G+PG DG G+PG EG PG +G P GV G Sbjct: 560 GPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVD 619 Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVG------EIGLDGLDGEDG------------DKGLP 2124 G +G G +G KG GFPG KG++G E+G+ G GEDG D G P Sbjct: 620 GIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPP 679 Query: 2125 GSSGEKGN---------PGRRGDKGP---------RGEKGER---GDVGIRGDPGNPGQD 2163 G GEKG PGR+G KG GEKG R G G RG+ G G Sbjct: 680 GLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPR 739 Query: 2164 SQERGPKGETGDLGPMGVPGRDGVPGGPGE------TGKNGGFGRRGPPGAKGNKGGPGQ 2217 Q RGP+G TG G G G DG G PGE G NG G +GPPG G G PG Sbjct: 740 GQ-RGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGH 798 Query: 2218 PGFEGEQGTRGAQGPAGP---AGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGE 2274 PG GE G +G GP GP GP G GE G G RG G G PGE+G G G++G Sbjct: 799 PGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 858 Query: 2275 PGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGT 2333 G+PGP G G GP G G G G+ G+ G G KG G G PGP G+PGE G G+ Sbjct: 859 KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 918 Query: 2334 TGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 GP G GR G GPPG G+KG PG GP GP G G Sbjct: 919 GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDG 956 Score = 279 bits (714), Expect = 3e-74 Identities = 161/349 (46%), Positives = 193/349 (55%), Gaps = 21/349 (6%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERG---PPGVNGTQGFQGCPGQRGVK 2094 G G +GP GS+GP+G PG G +G PG +G PG +G P G G QG G PG G Sbjct: 521 GMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSD 580 Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGE------R 2148 G G PG++G G G G G G G PG G KG G RG KG +GEKGE + Sbjct: 581 GPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFK 640 Query: 2149 GDVGIRGD------PGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGR 2202 GD+G++GD PG+ G+D E GPKG TG G G PG G G G G G GR Sbjct: 641 GDIGVKGDRGEVGVPGSRGEDGPE-GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR 699 Query: 2203 RGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE 2262 +GP KG+ G PG PG GE+G RG G +GP G G G +G GPRG+ G +GA G Sbjct: 700 QGP---KGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGT 756 Query: 2263 RGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPK 2322 G GP G GE G PGP+G G GP+G G G+DG+ G G++GE GF G GP Sbjct: 757 SGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL--PGHPGQRGEVGFQGKTGPP 814 Query: 2323 GNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 G PG G G G G G RG+ GPPG G++G PG G G KG+ G Sbjct: 815 GPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPG 863 Score = 278 bits (712), Expect = 5e-74 Identities = 162/365 (44%), Positives = 185/365 (50%), Gaps = 26/365 (7%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGV---NGTQGFQGCPG 2089 P +G+ G G G GP G PGE G G G EG G+ GPPG +G G +G PG Sbjct: 822 PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG 881 Query: 2090 QRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERG 2149 +RG+ G+ G PG KG G G G G G++G GS G G PGR G +GP G GE+G Sbjct: 882 ERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKG 941 Query: 2150 DVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPG---GPGETGKNGGFGRRGPP 2206 G +G G G+D + GP G G GP GV G DG G PG+ G G G GPP Sbjct: 942 VPGEKGPIGPTGRDGVQ-GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPP 1000 Query: 2207 GAKGNKGGPGQPGFEGEQGTRGAQGPAGPAG------------PPGLIGEQGISGPRGSG 2254 G G G GQPG G G GA+GP G G PPG IG QG+ GP G Sbjct: 1001 GPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEK 1060 Query: 2255 GAAG------APGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRR 2307 G G PG G GP G G G GP GG+GN GP GE G+ G G G +G Sbjct: 1061 GETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEP 1120 Query: 2308 GKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPK 2367 G KG RG G G G PGEPG G GP G G +GN GP G G G PG GP G Sbjct: 1121 GVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQD 1180 Query: 2368 GNRGD 2372 G +GD Sbjct: 1181 GAKGD 1185 Score = 278 bits (710), Expect = 8e-74 Identities = 161/357 (45%), Positives = 188/357 (52%), Gaps = 27/357 (7%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGV--- 2093 SG++G RG G GP+G G G RG G G G+ G G +G G G PG+RG+ Sbjct: 715 SGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGP 774 Query: 2094 KGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI 2153 +G GFPG KG G G DGL G G +G G G+ G PG G GP+G GE G +G Sbjct: 775 QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 834 Query: 2154 RGDPGNPGQDSQE-----RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208 RG PG PG ++ G +G GD GP G PG+DG G G G+ G G G PG Sbjct: 835 RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGL 894 Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2268 KGN+G G PG G G RGA G GP GPPG G Q GP G+ G G PGE+G GP Sbjct: 895 KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQ---GPPGAAGEKGVPGEKGPIGP 951 Query: 2269 LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGE 2327 GR G G G G G G GE GD G G G +G +G KGE G PG PGP G G+ Sbjct: 952 TGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQ 1011 Query: 2328 PGLNGTTGPKGIR------------GRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 PG G G G R G RG +GPPG +G + G PGP+G KG GD Sbjct: 1012 PGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ---GLPGPSGEKGETGD 1065 Score = 272 bits (695), Expect = 4e-72 Identities = 154/344 (44%), Positives = 188/344 (54%), Gaps = 30/344 (8%) Query: 2043 RGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGE 2102 RGP G +G G PG G G PG +G G+ GP G G QG G PG+ G +G G G Sbjct: 379 RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 438 Query: 2103 KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQ 2162 +G G+ G+ G G DG GLPG G +G+ G +G GP GE GERGD G Sbjct: 439 RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDG---------- 488 Query: 2163 DSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEG 2222 E GP+G G+ GP G+ G G PG PG G G G +GP G+ G +G PG PG +G Sbjct: 489 ---EIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQG 545 Query: 2223 EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKG 2282 GT+G GP G GP G G QG G G G+ G PG G+ GP G KG G GP+G Sbjct: 546 TPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQG 605 Query: 2283 GIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYP---------GPKGNPGEPGLNGT 2333 +G GPRG G DG G+ +G +G+KGE GFPG+ G G PG G +G Sbjct: 606 PLGYPGPRGVKGVDGIRGL--KGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGP 663 Query: 2334 TGPKGIRGRRGNSGPPGIVGQKGD------PGYPGPAGPKGNRG 2371 GPKG G G+ GPPG++G+KG PGYPG GPKG+ G Sbjct: 664 EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLG 707 Score = 270 bits (690), Expect = 2e-71 Identities = 157/393 (39%), Positives = 198/393 (50%), Gaps = 57/393 (14%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDG---YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094 G G G G GP G PG+DG RG+PG+ G PG G PG+ G +G G PG G Sbjct: 851 GTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 910 Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI- 2153 G RG G G +G G G +G PG++GEKG PG +G GP G G +G VG+ Sbjct: 911 GERGAAGSGGPIGP------PGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLP 964 Query: 2154 --------------RGDPGNPGQ-----DSQERGPKGETGDLGPMGVPGRDGVPGGPGET 2194 +G+ G+PGQ + E GP G G +GP+G PG G G PG Sbjct: 965 GPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGAR 1024 Query: 2195 GKNGGFGRRGPPGAKGNKGGPGQPGFEG---EQGTRGAQGPAGPAGPPGLIGEQGISGPR 2251 G G FG +G G +G G PG G +G G +G G GP GPPG G +G +GP Sbjct: 1025 GPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPN 1084 Query: 2252 GSGGAAGAPGERGRTGPLGRKGEPGE---PGPKGGIGNRGPRGETGDDGRDGV----GSE 2304 G+ G G PG G GP G KGEPGE PG +G G +GPRGE G+ G G G Sbjct: 1085 GADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1144 Query: 2305 GRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGN------------------S 2346 G +G G+ G G PGP G PG+PG G GP+G G +G+ + Sbjct: 1145 GPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGEN 1204 Query: 2347 GPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCAL 2379 GPPG +G++G G PG G +G +G D A+ Sbjct: 1205 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAI 1237 Score = 270 bits (689), Expect = 2e-71 Identities = 164/375 (43%), Positives = 189/375 (50%), Gaps = 44/375 (11%) Query: 2040 RGDRGPIGSIG---PKGIPGEDGYRGYPGDEGGPGERGPPGVNG------------TQGF 2084 RG GP+G G P G PG G +G GD G G RGP G+ G G Sbjct: 379 RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 438 Query: 2085 QGCPGQRGVKGSRGF------PGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGD 2138 +G PG GVKG RGF PGEKG G+ G GL G G+ G G GE G G G+ Sbjct: 439 RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 498 Query: 2139 KGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGG---PGETG 2195 GPRG G +G GI G PG G D + GPKG G G G PG+ G PG PG G Sbjct: 499 SGPRGLLGPKGPPGIPGPPGVRGMDGPQ-GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQG 557 Query: 2196 KNGGFGRRGP------PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGP---------PG 2240 G G +GP PG G+ G PG PG EG GT+G QGP+GP GP G Sbjct: 558 AIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKG 617 Query: 2241 LIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG 2300 + G +G+ G +G G G PG +G G G +GE G PG +G G GP+G TG G G Sbjct: 618 VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG 677 Query: 2301 V-GSEGRRGKKGERGFPGYP---GPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKG 2356 G G +GK G G PGYP GPKG+ G PG G +G KG RG G SGP G G G Sbjct: 678 PPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTG 737 Query: 2357 DPGYPGPAGPKGNRG 2371 G GP G G G Sbjct: 738 PRGQRGPRGATGKSG 752 Score = 269 bits (688), Expect = 3e-71 Identities = 162/381 (42%), Positives = 192/381 (50%), Gaps = 40/381 (10%) Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGG------PGERGPPGV---NGT 2081 G P G+ G +GP G+ G KG+PGE G G G +G PG GPPGV +G Sbjct: 919 GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGD 978 Query: 2082 QGFQGCPGQRGVKGSRGF------PGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGR 2135 +G G PGQ+G KG++G PG G VG+ G G DGE G +G G G KG+ G Sbjct: 979 KGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGT 1038 Query: 2136 RGDKGP------------RGEKGERGDVGIRGDPGNPGQ-----DSQERGPKGETGDLGP 2178 RG GP GEKGE GDVG G PG PG + GP+G G +G Sbjct: 1039 RGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN 1098 Query: 2179 MGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGP 2238 +G PG G PG G G G G +GP G +G KG GQPG G G +G G GP G Sbjct: 1099 LGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN 1158 Query: 2239 PGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGG------IGNRGPRGE 2292 PG +G G GP G GG G G +G G G G+PG PGP G +G RGP G Sbjct: 1159 PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1218 Query: 2293 TGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIV 2352 G +GR G +G +G G G PG GP G G G G G +G+ G G G PG Sbjct: 1219 PGSEGRQG--GKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGAT 1276 Query: 2353 GQKGDPGYPGPAGPKGNRGDS 2373 GQ G PG GP G G RGD+ Sbjct: 1277 GQAGPPGPVGPPGLPGLRGDA 1297 Score = 266 bits (681), Expect = 2e-70 Identities = 160/377 (42%), Positives = 195/377 (51%), Gaps = 50/377 (13%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G+ G+RG G IGP+G+PGE G RG G +G PG GPPGV G G QG G G +G Sbjct: 479 GEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEP 538 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157 G PG++G G GL G G G G G G+ G PG G GP G G+ G G +G+ Sbjct: 539 GPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQ 598 Query: 2158 GNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQ 2217 G G +GP G G G GV G G+ G GE G++G G +G G KG++G G Sbjct: 599 GPSGP----QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV 654 Query: 2218 PGFEGE---QGTRGAQGPAGPAGPPGLIGEQGI------------SGPRGSGGAAGAPG- 2261 PG GE +G +G GP G GPPGL+GE+G GP+GS G G PG Sbjct: 655 PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGA 714 Query: 2262 --ERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPG- 2317 E+G G G+ G GE GP G G RGPRG TG G G G +G G GERG PG Sbjct: 715 SGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGP 774 Query: 2318 -----YPGPKGN---------PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK-------- 2355 +PGPKG PG PG G G +G+ G GPPG+VG + Sbjct: 775 QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEV---GFQGKTGPPGPPGVVGPQGAAGETGP 831 Query: 2356 -GDPGYPGPAGPKGNRG 2371 G+ G+PGP GP G +G Sbjct: 832 MGERGHPGPPGPPGEQG 848 Score = 263 bits (673), Expect = 2e-69 Identities = 160/395 (40%), Positives = 195/395 (49%), Gaps = 57/395 (14%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQR- 2091 P +G+ G +G G GP G PGE G G G G PG +GPPG G G G PGQR Sbjct: 744 PRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRG 803 Query: 2092 --------------GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRG 2137 GV G +G GE G +GE G G G G++GLPG++G++G +G Sbjct: 804 EVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT---KG 860 Query: 2138 DKGPRGEKGERGDVGIRGDPGNPGQDSQERGP-----KGETGDLGPMGVPGRDGVPGGPG 2192 D GP G G+ G G+RG PG G GP +G +G GP G PG G G G Sbjct: 861 DPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGG 920 Query: 2193 ETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPA---GPAGPPGLIGEQGISG 2249 G G G +GPPGA G KG PG+ G G G G QGP GPAGPPG+ GE G G Sbjct: 921 PIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 980 Query: 2250 PRGSGGAAGAPGERGR------TGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG--- 2300 G G G G +G GP+G G+PG G G G RGP+G G G +G Sbjct: 981 EVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRG 1040 Query: 2301 -------VGSEGRRGKKGERGFPGYPGPKGNPGEP------GLNGTTGPKGIRGRRGNSG 2347 +G +G G GE+G G GP G PG P G NG GP+G G GN G Sbjct: 1041 FNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLG 1100 Query: 2348 PPGIVGQ---------KGDPGYPGPAGPKGNRGDS 2373 PPG G+ +G+PG GP G +G +G+S Sbjct: 1101 PPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGES 1135 Score = 241 bits (616), Expect = 6e-63 Identities = 148/362 (40%), Positives = 178/362 (49%), Gaps = 35/362 (9%) Query: 2044 GPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK-------GS 2096 GP G GP G+ G G +G PG G PGERGPPG G G G PG G GS Sbjct: 292 GPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGS 351 Query: 2097 RGFPGEKGEV--------------GEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142 G G+KG V + L G G G G PG G+ G+PG +G+ G Sbjct: 352 GG--GDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 409 Query: 2143 GEKGERGDVGIRGDPGNPGQDSQER--GPKGETGDLGPMGVPGRDGVPGGPGETGKNGGF 2200 G +G RG G+ G PG G+ + G +G GD G G G DG+PG PGE G G Sbjct: 410 GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDT 469 Query: 2201 GRRG---PPGAKGNKGGPGQ---PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSG 2254 G +G PPG G +G G+ G GE G RG GP GP G PG G +G+ GP+G Sbjct: 470 GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPK 529 Query: 2255 GAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV----GSEGRRGKK 2310 G+ G GE G G G G G PGP+G IG G +G G G G+ G G GK+ Sbjct: 530 GSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKE 589 Query: 2311 GERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNR 2370 G G G GP G G G G G KG+ G RG G G G+ G PG+ G G KG+R Sbjct: 590 GPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDR 649 Query: 2371 GD 2372 G+ Sbjct: 650 GE 651 Score = 223 bits (569), Expect = 2e-57 Identities = 139/347 (40%), Positives = 172/347 (49%), Gaps = 43/347 (12%) Query: 2050 GPKGIPGEDG----------YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGF 2099 GP+G+ GE G G PG EG G GPPG+ G G G PG+RG G G Sbjct: 270 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 329 Query: 2100 PGEKGEVGEIGLDGL-----DGEDGDKGLPGSSGEKG-----NPGRRGDKGPRGEKGERG 2149 PG G G G + GDKG ++ E R +GP G G G Sbjct: 330 PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTG 389 Query: 2150 DVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAK 2209 G G PG+PG KGE+GDLGP G G G+ G PG+ G RRG GA Sbjct: 390 RPGPLGQPGSPGL-------KGESGDLGPQGPRGPQGLTGPPGKAG------RRGRAGAD 436 Query: 2210 GNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPL 2269 G +G PG PG +G++G G G G G G G QG+ GP G G ERG G + Sbjct: 437 GARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDG------ERGDDGEI 490 Query: 2270 GRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGE- 2327 G +G PGE GP+G +G +GP G G G G+ G +G +G G +G PG PG +G PG Sbjct: 491 GPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQ 550 Query: 2328 --PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 PG G GP G +G +G G PG+ G G PG+PG GP G +G+ Sbjct: 551 GLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN 597 Score = 189 bits (479), Expect = 5e-47 Identities = 114/263 (43%), Positives = 133/263 (50%), Gaps = 26/263 (9%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G+ G G G GPKG G+DG +G PG G PG+ GPPG G +G G G RG G Sbjct: 1133 GESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEP 1192 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKG------------PRGEK 2145 G PG G GE G G G+ G G PGS G +G G +GD G P G Sbjct: 1193 GQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA 1252 Query: 2146 GERGDVGIRGDPGNPGQDSQE--RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRR 2203 G+ G G+RG PG+ GQ + G G G +GP G+PG G G GE G G G Sbjct: 1253 GKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLI 1312 Query: 2204 GPPGAKGNKG-----GP-GQPGFEGEQGTRGAQGP---AGPAGPPGLIGEQGISGPRGSG 2254 GPPG +G KG GP G PG +GE G GA GP GP PGL G G G +G+ Sbjct: 1313 GPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP---PGLPGPAGPKGAKGAT 1369 Query: 2255 GAAGAPGERGRTGPLGRKGEPGE 2277 G G GE+G GP G G PGE Sbjct: 1370 GPGGPKGEKGVQGPPGHPGPPGE 1392 Score = 171 bits (432), Expect = 1e-41 Identities = 101/228 (44%), Positives = 118/228 (51%), Gaps = 10/228 (4%) Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQ 2090 G P G +GDRG G G G PG G G PG G+RGP G G++G QG G Sbjct: 1174 GGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP---LGKRGPAGSPGSEGRQGGKGA 1230 Query: 2091 RGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD 2150 +G G+ G PG+ G VG G G G DG +GLPGS G++G PG G GP G G G Sbjct: 1231 KGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGL 1290 Query: 2151 VGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKG 2210 G+RGD G G E+G G G +GP G G G G PG G G G G PGA G Sbjct: 1291 PGLRGDAGAKG----EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASG 1346 Query: 2211 NKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAG 2258 G G PG G G +GA+G GP GP GE+G+ GP G G G Sbjct: 1347 PIGPGGPPGLPGPAGPKGAKGATGPGGPK---GEKGVQGPPGHPGPPG 1391 Score = 149 bits (375), Expect = 6e-35 Identities = 98/248 (39%), Positives = 123/248 (49%), Gaps = 18/248 (7%) Query: 2133 PGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPG 2192 P + GPRG KGE+G+ + +PG GP G G G +G PG G PG G Sbjct: 263 PQSQAAHGPRGLKGEKGEPAVL-EPG-----MLVEGPPGPEGPAGLIGPPGIQGNPGPVG 316 Query: 2193 ETGKNGGFGRRGPPGAKGNKGGPGQP-----GFEGEQGTRGAQGPAGPAGPPGLIGEQGI 2247 + G+ G GR G PG+ G G PG F G +G A A ++ + + Sbjct: 317 DPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARL 376 Query: 2248 S--GPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEG 2305 + GP G G G PG G+ G G KGE G+ GP+G RGP+G TG G+ G G Sbjct: 377 ALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGP---RGPQGLTGPPGK--AGRRG 431 Query: 2306 RRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAG 2365 R G G RG PG PG KG+ G GL G G KG RG G G PG G+ G+ G G G Sbjct: 432 RAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIG 491 Query: 2366 PKGNRGDS 2373 P+G G+S Sbjct: 492 PRGLPGES 499 Score = 108 bits (271), Expect = 6e-23 Identities = 67/164 (40%), Positives = 80/164 (48%), Gaps = 9/164 (5%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGT---QGFQGCPGQRGVK 2094 GQ+G G G GP G G G G GD G GE+G PG+ G G QG G RG+ Sbjct: 1268 GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1327 Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154 G +G PG+KGE+G G G G G GLPG +G KG G G GP+GEKG +G G Sbjct: 1328 GPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHP 1387 Query: 2155 GDPGNPGQDSQERGPKGETGDLGPMGVPGRD------GVPGGPG 2192 G PG Q + PK + + D G PG PG Sbjct: 1388 GPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1431 Score = 54.3 bits (129), Expect = 2e-06 Identities = 32/76 (42%), Positives = 37/76 (48%), Gaps = 4/76 (5%) Query: 2303 SEGRRGKKGERGFPGYPGP----KGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDP 2358 + G RG KGE+G P P +G PG G G GP GI+G G G PG G G Sbjct: 268 AHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA 327 Query: 2359 GYPGPAGPKGNRGDSI 2374 G PG G G G S+ Sbjct: 328 GLPGSDGAPGPPGTSL 343 Score = 39.3 bits (90), Expect = 0.063 Identities = 41/124 (33%), Positives = 48/124 (38%), Gaps = 31/124 (25%) Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQ 2090 G P G G +G G+ GP G GE G +G PG G PGE Q P Q Sbjct: 1351 GGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGE----------VIQPLPIQ 1400 Query: 2091 ------RGVKGSR-----------GFPGEKGEVGEI--GLDGLDGEDGDKGLPGSSGEKG 2131 R V GSR G PG G + EI LD L E P +G + Sbjct: 1401 MPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRP--TGTQD 1458 Query: 2132 NPGR 2135 +P R Sbjct: 1459 SPAR 1462 >gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo sapiens] Length = 1736 Score = 282 bits (721), Expect = 4e-75 Identities = 166/361 (45%), Positives = 191/361 (52%), Gaps = 39/361 (10%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGD------EGGPGERGPPGVNGTQGFQGCPGQR 2091 G RG GP G IG +G+PG G +G GD G PG RGP G NG G QG PG Sbjct: 1144 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG-- 1201 Query: 2092 GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD- 2150 GV G+ G PGEKGE GE G G+ GE G KG G GEKG G+ G+ GP G KG GD Sbjct: 1202 GV-GNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD 1260 Query: 2151 --------VGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGR 2202 VG GDPG PG+ RG G GD G G PG+ G PG GE G G G+ Sbjct: 1261 GPKGNPGPVGFPGDPGPPGEGGP-RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGK 1319 Query: 2203 RGP---PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGA 2259 RGP PG++G +GG G G G G G GP GPAGP G G G+ G GS G G Sbjct: 1320 RGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGR 1379 Query: 2260 PGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYP 2319 PG G+ GP G G PG PG +G G +G +G G G +G G +G+KG+RG PG Sbjct: 1380 PGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL--IGPPGEQGEKGDRGLPGPQ 1437 Query: 2320 GPKGNPGE---------------PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPA 2364 G G GE PGL G GPKG +G G GP G G +G PG+PGP Sbjct: 1438 GSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPP 1497 Query: 2365 G 2365 G Sbjct: 1498 G 1498 Score = 281 bits (719), Expect = 7e-75 Identities = 160/348 (45%), Positives = 190/348 (54%), Gaps = 17/348 (4%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G+ G GP G IGP G PG G G PG G G G G GT+GF G PG G++G Sbjct: 1102 GEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLP 1161 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPG---SSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154 G GEKGE G++G G G G +G G + G +G PG G+ GP GEKGE G+ G Sbjct: 1162 GPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSP 1221 Query: 2155 GDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGG 2214 G G PG +GP+GE G+ G G PG G PG G TG +G G GP G G+ G Sbjct: 1222 GIQGEPGV----KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGP 1277 Query: 2215 PGQPGFEGEQGT---RGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGR 2271 PG+ G G+ G RG G G G PG GE G GP G G AG+PG GR G G Sbjct: 1278 PGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGA 1337 Query: 2272 KGEPGE---PGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGE 2327 KG+PG PG G +G GP G+ G DG G+ GS G++G+ G G G PGP G PG Sbjct: 1338 KGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGL 1397 Query: 2328 PGLNGTTGPKGIRGRRGNSG---PPGIVGQKGDPGYPGPAGPKGNRGD 2372 PGL G G KG +G G G PPG G+KGD G PGP G G +G+ Sbjct: 1398 PGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGE 1445 Score = 281 bits (718), Expect = 9e-75 Identities = 173/398 (43%), Positives = 198/398 (49%), Gaps = 65/398 (16%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERG---------------PPGVNGTQ 2082 G G++GP G G G+PG DG G+PG EG PG +G P GV G Sbjct: 667 GPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVD 726 Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVG------EIGLDGLDGEDG------------DKGLP 2124 G +G G +G KG GFPG KG++G E+G+ G GEDG D G P Sbjct: 727 GIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPP 786 Query: 2125 GSSGEKGN---------PGRRGDKGP---------RGEKGER---GDVGIRGDPGNPGQD 2163 G GEKG PGR+G KG GEKG R G G RG+ G G Sbjct: 787 GLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPR 846 Query: 2164 SQERGPKGETGDLGPMGVPGRDGVPGGPGE------TGKNGGFGRRGPPGAKGNKGGPGQ 2217 Q RGP+G TG G G G DG G PGE G NG G +GPPG G G PG Sbjct: 847 GQ-RGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGH 905 Query: 2218 PGFEGEQGTRGAQGPAGP---AGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGE 2274 PG GE G +G GP GP GP G GE G G RG G G PGE+G G G++G Sbjct: 906 PGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 965 Query: 2275 PGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGT 2333 G+PGP G G GP G G G G+ G+ G G KG G G PGP G+PGE G G+ Sbjct: 966 KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 1025 Query: 2334 TGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 GP G GR G GPPG G+KG PG GP GP G G Sbjct: 1026 GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDG 1063 Score = 279 bits (714), Expect = 3e-74 Identities = 161/349 (46%), Positives = 193/349 (55%), Gaps = 21/349 (6%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERG---PPGVNGTQGFQGCPGQRGVK 2094 G G +GP GS+GP+G PG G +G PG +G PG +G P G G QG G PG G Sbjct: 628 GMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSD 687 Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGE------R 2148 G G PG++G G G G G G G PG G KG G RG KG +GEKGE + Sbjct: 688 GPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFK 747 Query: 2149 GDVGIRGD------PGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGR 2202 GD+G++GD PG+ G+D E GPKG TG G G PG G G G G G GR Sbjct: 748 GDIGVKGDRGEVGVPGSRGEDGPE-GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR 806 Query: 2203 RGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE 2262 +GP KG+ G PG PG GE+G RG G +GP G G G +G GPRG+ G +GA G Sbjct: 807 QGP---KGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGT 863 Query: 2263 RGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPK 2322 G GP G GE G PGP+G G GP+G G G+DG+ G G++GE GF G GP Sbjct: 864 SGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL--PGHPGQRGEVGFQGKTGPP 921 Query: 2323 GNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 G PG G G G G G RG+ GPPG G++G PG G G KG+ G Sbjct: 922 GPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPG 970 Score = 278 bits (712), Expect = 5e-74 Identities = 162/365 (44%), Positives = 185/365 (50%), Gaps = 26/365 (7%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGV---NGTQGFQGCPG 2089 P +G+ G G G GP G PGE G G G EG G+ GPPG +G G +G PG Sbjct: 929 PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG 988 Query: 2090 QRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERG 2149 +RG+ G+ G PG KG G G G G G++G GS G G PGR G +GP G GE+G Sbjct: 989 ERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKG 1048 Query: 2150 DVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPG---GPGETGKNGGFGRRGPP 2206 G +G G G+D + GP G G GP GV G DG G PG+ G G G GPP Sbjct: 1049 VPGEKGPIGPTGRDGVQ-GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPP 1107 Query: 2207 GAKGNKGGPGQPGFEGEQGTRGAQGPAGPAG------------PPGLIGEQGISGPRGSG 2254 G G G GQPG G G GA+GP G G PPG IG QG+ GP G Sbjct: 1108 GPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEK 1167 Query: 2255 GAAG------APGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRR 2307 G G PG G GP G G G GP GG+GN GP GE G+ G G G +G Sbjct: 1168 GETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEP 1227 Query: 2308 GKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPK 2367 G KG RG G G G PGEPG G GP G G +GN GP G G G PG GP G Sbjct: 1228 GVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQD 1287 Query: 2368 GNRGD 2372 G +GD Sbjct: 1288 GAKGD 1292 Score = 278 bits (710), Expect = 8e-74 Identities = 161/357 (45%), Positives = 188/357 (52%), Gaps = 27/357 (7%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGV--- 2093 SG++G RG G GP+G G G RG G G G+ G G +G G G PG+RG+ Sbjct: 822 SGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGP 881 Query: 2094 KGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI 2153 +G GFPG KG G G DGL G G +G G G+ G PG G GP+G GE G +G Sbjct: 882 QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 941 Query: 2154 RGDPGNPGQDSQE-----RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208 RG PG PG ++ G +G GD GP G PG+DG G G G+ G G G PG Sbjct: 942 RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGL 1001 Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2268 KGN+G G PG G G RGA G GP GPPG G Q GP G+ G G PGE+G GP Sbjct: 1002 KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQ---GPPGAAGEKGVPGEKGPIGP 1058 Query: 2269 LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGE 2327 GR G G G G G G GE GD G G G +G +G KGE G PG PGP G G+ Sbjct: 1059 TGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQ 1118 Query: 2328 PGLNGTTGPKGIR------------GRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 PG G G G R G RG +GPPG +G + G PGP+G KG GD Sbjct: 1119 PGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ---GLPGPSGEKGETGD 1172 Score = 272 bits (695), Expect = 4e-72 Identities = 154/344 (44%), Positives = 188/344 (54%), Gaps = 30/344 (8%) Query: 2043 RGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGE 2102 RGP G +G G PG G G PG +G G+ GP G G QG G PG+ G +G G G Sbjct: 486 RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 545 Query: 2103 KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQ 2162 +G G+ G+ G G DG GLPG G +G+ G +G GP GE GERGD G Sbjct: 546 RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDG---------- 595 Query: 2163 DSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEG 2222 E GP+G G+ GP G+ G G PG PG G G G +GP G+ G +G PG PG +G Sbjct: 596 ---EIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQG 652 Query: 2223 EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKG 2282 GT+G GP G GP G G QG G G G+ G PG G+ GP G KG G GP+G Sbjct: 653 TPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQG 712 Query: 2283 GIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYP---------GPKGNPGEPGLNGT 2333 +G GPRG G DG G+ +G +G+KGE GFPG+ G G PG G +G Sbjct: 713 PLGYPGPRGVKGVDGIRGL--KGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGP 770 Query: 2334 TGPKGIRGRRGNSGPPGIVGQKGD------PGYPGPAGPKGNRG 2371 GPKG G G+ GPPG++G+KG PGYPG GPKG+ G Sbjct: 771 EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLG 814 Score = 270 bits (690), Expect = 2e-71 Identities = 157/393 (39%), Positives = 198/393 (50%), Gaps = 57/393 (14%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDG---YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094 G G G G GP G PG+DG RG+PG+ G PG G PG+ G +G G PG G Sbjct: 958 GTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 1017 Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI- 2153 G RG G G +G G G +G PG++GEKG PG +G GP G G +G VG+ Sbjct: 1018 GERGAAGSGGPIGP------PGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLP 1071 Query: 2154 --------------RGDPGNPGQ-----DSQERGPKGETGDLGPMGVPGRDGVPGGPGET 2194 +G+ G+PGQ + E GP G G +GP+G PG G G PG Sbjct: 1072 GPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGAR 1131 Query: 2195 GKNGGFGRRGPPGAKGNKGGPGQPGFEG---EQGTRGAQGPAGPAGPPGLIGEQGISGPR 2251 G G FG +G G +G G PG G +G G +G G GP GPPG G +G +GP Sbjct: 1132 GPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPN 1191 Query: 2252 GSGGAAGAPGERGRTGPLGRKGEPGE---PGPKGGIGNRGPRGETGDDGRDGV----GSE 2304 G+ G G PG G GP G KGEPGE PG +G G +GPRGE G+ G G G Sbjct: 1192 GADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1251 Query: 2305 GRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGN------------------S 2346 G +G G+ G G PGP G PG+PG G GP+G G +G+ + Sbjct: 1252 GPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGEN 1311 Query: 2347 GPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCAL 2379 GPPG +G++G G PG G +G +G D A+ Sbjct: 1312 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAI 1344 Score = 270 bits (689), Expect = 2e-71 Identities = 164/375 (43%), Positives = 189/375 (50%), Gaps = 44/375 (11%) Query: 2040 RGDRGPIGSIG---PKGIPGEDGYRGYPGDEGGPGERGPPGVNG------------TQGF 2084 RG GP+G G P G PG G +G GD G G RGP G+ G G Sbjct: 486 RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 545 Query: 2085 QGCPGQRGVKGSRGF------PGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGD 2138 +G PG GVKG RGF PGEKG G+ G GL G G+ G G GE G G G+ Sbjct: 546 RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 605 Query: 2139 KGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGG---PGETG 2195 GPRG G +G GI G PG G D + GPKG G G G PG+ G PG PG G Sbjct: 606 SGPRGLLGPKGPPGIPGPPGVRGMDGPQ-GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQG 664 Query: 2196 KNGGFGRRGP------PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGP---------PG 2240 G G +GP PG G+ G PG PG EG GT+G QGP+GP GP G Sbjct: 665 AIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKG 724 Query: 2241 LIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG 2300 + G +G+ G +G G G PG +G G G +GE G PG +G G GP+G TG G G Sbjct: 725 VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG 784 Query: 2301 V-GSEGRRGKKGERGFPGYP---GPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKG 2356 G G +GK G G PGYP GPKG+ G PG G +G KG RG G SGP G G G Sbjct: 785 PPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTG 844 Query: 2357 DPGYPGPAGPKGNRG 2371 G GP G G G Sbjct: 845 PRGQRGPRGATGKSG 859 Score = 269 bits (688), Expect = 3e-71 Identities = 162/381 (42%), Positives = 192/381 (50%), Gaps = 40/381 (10%) Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGG------PGERGPPGV---NGT 2081 G P G+ G +GP G+ G KG+PGE G G G +G PG GPPGV +G Sbjct: 1026 GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGD 1085 Query: 2082 QGFQGCPGQRGVKGSRGF------PGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGR 2135 +G G PGQ+G KG++G PG G VG+ G G DGE G +G G G KG+ G Sbjct: 1086 KGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGT 1145 Query: 2136 RGDKGP------------RGEKGERGDVGIRGDPGNPGQ-----DSQERGPKGETGDLGP 2178 RG GP GEKGE GDVG G PG PG + GP+G G +G Sbjct: 1146 RGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN 1205 Query: 2179 MGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGP 2238 +G PG G PG G G G G +GP G +G KG GQPG G G +G G GP G Sbjct: 1206 LGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN 1265 Query: 2239 PGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGG------IGNRGPRGE 2292 PG +G G GP G GG G G +G G G G+PG PGP G +G RGP G Sbjct: 1266 PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1325 Query: 2293 TGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIV 2352 G +GR G +G +G G G PG GP G G G G G +G+ G G G PG Sbjct: 1326 PGSEGRQG--GKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGAT 1383 Query: 2353 GQKGDPGYPGPAGPKGNRGDS 2373 GQ G PG GP G G RGD+ Sbjct: 1384 GQAGPPGPVGPPGLPGLRGDA 1404 Score = 266 bits (681), Expect = 2e-70 Identities = 160/377 (42%), Positives = 195/377 (51%), Gaps = 50/377 (13%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G+ G+RG G IGP+G+PGE G RG G +G PG GPPGV G G QG G G +G Sbjct: 586 GEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEP 645 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157 G PG++G G GL G G G G G G+ G PG G GP G G+ G G +G+ Sbjct: 646 GPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQ 705 Query: 2158 GNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQ 2217 G G +GP G G G GV G G+ G GE G++G G +G G KG++G G Sbjct: 706 GPSGP----QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV 761 Query: 2218 PGFEGE---QGTRGAQGPAGPAGPPGLIGEQGI------------SGPRGSGGAAGAPG- 2261 PG GE +G +G GP G GPPGL+GE+G GP+GS G G PG Sbjct: 762 PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGA 821 Query: 2262 --ERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPG- 2317 E+G G G+ G GE GP G G RGPRG TG G G G +G G GERG PG Sbjct: 822 SGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGP 881 Query: 2318 -----YPGPKGN---------PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK-------- 2355 +PGPKG PG PG G G +G+ G GPPG+VG + Sbjct: 882 QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEV---GFQGKTGPPGPPGVVGPQGAAGETGP 938 Query: 2356 -GDPGYPGPAGPKGNRG 2371 G+ G+PGP GP G +G Sbjct: 939 MGERGHPGPPGPPGEQG 955 Score = 263 bits (673), Expect = 2e-69 Identities = 160/395 (40%), Positives = 195/395 (49%), Gaps = 57/395 (14%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQR- 2091 P +G+ G +G G GP G PGE G G G G PG +GPPG G G G PGQR Sbjct: 851 PRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRG 910 Query: 2092 --------------GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRG 2137 GV G +G GE G +GE G G G G++GLPG++G++G +G Sbjct: 911 EVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT---KG 967 Query: 2138 DKGPRGEKGERGDVGIRGDPGNPGQDSQERGP-----KGETGDLGPMGVPGRDGVPGGPG 2192 D GP G G+ G G+RG PG G GP +G +G GP G PG G G G Sbjct: 968 DPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGG 1027 Query: 2193 ETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPA---GPAGPPGLIGEQGISG 2249 G G G +GPPGA G KG PG+ G G G G QGP GPAGPPG+ GE G G Sbjct: 1028 PIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 1087 Query: 2250 PRGSGGAAGAPGERGR------TGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG--- 2300 G G G G +G GP+G G+PG G G G RGP+G G G +G Sbjct: 1088 EVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRG 1147 Query: 2301 -------VGSEGRRGKKGERGFPGYPGPKGNPGEP------GLNGTTGPKGIRGRRGNSG 2347 +G +G G GE+G G GP G PG P G NG GP+G G GN G Sbjct: 1148 FNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLG 1207 Query: 2348 PPGIVGQ---------KGDPGYPGPAGPKGNRGDS 2373 PPG G+ +G+PG GP G +G +G+S Sbjct: 1208 PPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGES 1242 Score = 241 bits (616), Expect = 6e-63 Identities = 148/362 (40%), Positives = 178/362 (49%), Gaps = 35/362 (9%) Query: 2044 GPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK-------GS 2096 GP G GP G+ G G +G PG G PGERGPPG G G G PG G GS Sbjct: 399 GPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGS 458 Query: 2097 RGFPGEKGEV--------------GEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142 G G+KG V + L G G G G PG G+ G+PG +G+ G Sbjct: 459 GG--GDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 516 Query: 2143 GEKGERGDVGIRGDPGNPGQDSQER--GPKGETGDLGPMGVPGRDGVPGGPGETGKNGGF 2200 G +G RG G+ G PG G+ + G +G GD G G G DG+PG PGE G G Sbjct: 517 GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDT 576 Query: 2201 GRRG---PPGAKGNKGGPGQ---PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSG 2254 G +G PPG G +G G+ G GE G RG GP GP G PG G +G+ GP+G Sbjct: 577 GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPK 636 Query: 2255 GAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV----GSEGRRGKK 2310 G+ G GE G G G G G PGP+G IG G +G G G G+ G G GK+ Sbjct: 637 GSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKE 696 Query: 2311 GERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNR 2370 G G G GP G G G G G KG+ G RG G G G+ G PG+ G G KG+R Sbjct: 697 GPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDR 756 Query: 2371 GD 2372 G+ Sbjct: 757 GE 758 Score = 223 bits (569), Expect = 2e-57 Identities = 139/347 (40%), Positives = 172/347 (49%), Gaps = 43/347 (12%) Query: 2050 GPKGIPGEDG----------YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGF 2099 GP+G+ GE G G PG EG G GPPG+ G G G PG+RG G G Sbjct: 377 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 436 Query: 2100 PGEKGEVGEIGLDGL-----DGEDGDKGLPGSSGEKG-----NPGRRGDKGPRGEKGERG 2149 PG G G G + GDKG ++ E R +GP G G G Sbjct: 437 PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTG 496 Query: 2150 DVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAK 2209 G G PG+PG KGE+GDLGP G G G+ G PG+ G RRG GA Sbjct: 497 RPGPLGQPGSPGL-------KGESGDLGPQGPRGPQGLTGPPGKAG------RRGRAGAD 543 Query: 2210 GNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPL 2269 G +G PG PG +G++G G G G G G G QG+ GP G G ERG G + Sbjct: 544 GARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDG------ERGDDGEI 597 Query: 2270 GRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGE- 2327 G +G PGE GP+G +G +GP G G G G+ G +G +G G +G PG PG +G PG Sbjct: 598 GPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQ 657 Query: 2328 --PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 PG G GP G +G +G G PG+ G G PG+PG GP G +G+ Sbjct: 658 GLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN 704 Score = 189 bits (479), Expect = 5e-47 Identities = 114/263 (43%), Positives = 133/263 (50%), Gaps = 26/263 (9%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G+ G G G GPKG G+DG +G PG G PG+ GPPG G +G G G RG G Sbjct: 1240 GESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEP 1299 Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKG------------PRGEK 2145 G PG G GE G G G+ G G PGS G +G G +GD G P G Sbjct: 1300 GQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA 1359 Query: 2146 GERGDVGIRGDPGNPGQDSQE--RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRR 2203 G+ G G+RG PG+ GQ + G G G +GP G+PG G G GE G G G Sbjct: 1360 GKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLI 1419 Query: 2204 GPPGAKGNKG-----GP-GQPGFEGEQGTRGAQGP---AGPAGPPGLIGEQGISGPRGSG 2254 GPPG +G KG GP G PG +GE G GA GP GP PGL G G G +G+ Sbjct: 1420 GPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP---PGLPGPAGPKGAKGAT 1476 Query: 2255 GAAGAPGERGRTGPLGRKGEPGE 2277 G G GE+G GP G G PGE Sbjct: 1477 GPGGPKGEKGVQGPPGHPGPPGE 1499 Score = 171 bits (432), Expect = 1e-41 Identities = 101/228 (44%), Positives = 118/228 (51%), Gaps = 10/228 (4%) Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQ 2090 G P G +GDRG G G G PG G G PG G+RGP G G++G QG G Sbjct: 1281 GGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP---LGKRGPAGSPGSEGRQGGKGA 1337 Query: 2091 RGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD 2150 +G G+ G PG+ G VG G G G DG +GLPGS G++G PG G GP G G G Sbjct: 1338 KGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGL 1397 Query: 2151 VGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKG 2210 G+RGD G G E+G G G +GP G G G G PG G G G G PGA G Sbjct: 1398 PGLRGDAGAKG----EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASG 1453 Query: 2211 NKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAG 2258 G G PG G G +GA+G GP GP GE+G+ GP G G G Sbjct: 1454 PIGPGGPPGLPGPAGPKGAKGATGPGGPK---GEKGVQGPPGHPGPPG 1498 Score = 149 bits (377), Expect = 3e-35 Identities = 101/257 (39%), Positives = 126/257 (49%), Gaps = 19/257 (7%) Query: 2124 PGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPG 2183 P S E + G GPRG KGE+G+ + +PG GP G G G +G PG Sbjct: 362 PALSAETAHSGAAAH-GPRGLKGEKGEPAVL-EPG-----MLVEGPPGPEGPAGLIGPPG 414 Query: 2184 RDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQP-----GFEGEQGTRGAQGPAGPAGP 2238 G PG G+ G+ G GR G PG+ G G PG F G +G A A Sbjct: 415 IQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQA 474 Query: 2239 PGLIGEQGIS--GPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDD 2296 ++ + ++ GP G G G PG G+ G G KGE G+ GP+G RGP+G TG Sbjct: 475 QAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGP---RGPQGLTGPP 531 Query: 2297 GRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKG 2356 G+ G GR G G RG PG PG KG+ G GL G G KG RG G G PG G+ G Sbjct: 532 GK--AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDG 589 Query: 2357 DPGYPGPAGPKGNRGDS 2373 + G G GP+G G+S Sbjct: 590 ERGDDGEIGPRGLPGES 606 Score = 108 bits (271), Expect = 6e-23 Identities = 67/164 (40%), Positives = 80/164 (48%), Gaps = 9/164 (5%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGT---QGFQGCPGQRGVK 2094 GQ+G G G GP G G G G GD G GE+G PG+ G G QG G RG+ Sbjct: 1375 GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1434 Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154 G +G PG+KGE+G G G G G GLPG +G KG G G GP+GEKG +G G Sbjct: 1435 GPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHP 1494 Query: 2155 GDPGNPGQDSQERGPKGETGDLGPMGVPGRD------GVPGGPG 2192 G PG Q + PK + + D G PG PG Sbjct: 1495 GPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1538 Score = 57.4 bits (137), Expect = 2e-07 Identities = 33/86 (38%), Positives = 40/86 (46%), Gaps = 4/86 (4%) Query: 2293 TGDDGRDGVGSEGRRGKKGERGFPGYPGP----KGNPGEPGLNGTTGPKGIRGRRGNSGP 2348 + + G + G RG KGE+G P P +G PG G G GP GI+G G G Sbjct: 365 SAETAHSGAAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGD 424 Query: 2349 PGIVGQKGDPGYPGPAGPKGNRGDSI 2374 PG G G G PG G G G S+ Sbjct: 425 PGERGPPGRAGLPGSDGAPGPPGTSL 450 Score = 39.3 bits (90), Expect = 0.063 Identities = 41/124 (33%), Positives = 48/124 (38%), Gaps = 31/124 (25%) Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQ 2090 G P G G +G G+ GP G GE G +G PG G PGE Q P Q Sbjct: 1458 GGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGE----------VIQPLPIQ 1507 Query: 2091 ------RGVKGSR-----------GFPGEKGEVGEI--GLDGLDGEDGDKGLPGSSGEKG 2131 R V GSR G PG G + EI LD L E P +G + Sbjct: 1508 MPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRP--TGTQD 1565 Query: 2132 NPGR 2135 +P R Sbjct: 1566 SPAR 1569 >gi|48762934 alpha 2 type I collagen [Homo sapiens] Length = 1366 Score = 280 bits (715), Expect = 2e-74 Identities = 167/412 (40%), Positives = 196/412 (47%), Gaps = 77/412 (18%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096 SG G GPIGS GP G PG DG +G PG G G GP G +G G +G G G KG Sbjct: 597 SGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGE 656 Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGDKGLP------------------GSSGEKGNPGRRGD 2138 +G PG +GE+G G DG G G G P G +G +G+PG RG+ Sbjct: 657 KGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGE 716 Query: 2139 KGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVP---------- 2188 GP G G G G G PG G+ +GPKGE G +GP G G G Sbjct: 717 VGPAGPNGFAGPAGAAGQPGAKGERG-AKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAG 775 Query: 2189 -----GGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGP-------- 2235 G PG TG G GR GPPG G G PG PG G++G RG +G GP Sbjct: 776 SRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVG 835 Query: 2236 -AGPPGLIGEQGISGPRGSGGAAGAPGER---------------------------GRTG 2267 GPPG GE+G SG G+ G G PG + G G Sbjct: 836 AVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPG 895 Query: 2268 PLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-------VGSEGRRGKKGERGFPGYPG 2320 PLG G PG GP G +G+ G G G+ GRDG G +G+ G KGERG+PG G Sbjct: 896 PLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIG 955 Query: 2321 PKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 P G G PG +G GP G G RG +GP G VG G G GP+GP+G RGD Sbjct: 956 PVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGD 1007 Score = 269 bits (688), Expect = 3e-71 Identities = 159/364 (43%), Positives = 187/364 (51%), Gaps = 29/364 (7%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPG---EDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPG 2089 P G+ G++G GS GP+G PG E+G RG G+ G G GPPG+ G+ G +G PG Sbjct: 350 PAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPG 409 Query: 2090 QRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERG 2149 G G G PG +G G G+ G +G+ G G PG G +G PG G+ GP G++G G Sbjct: 410 ADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVG 469 Query: 2150 DVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAK 2209 GI G PG G G +GE G++G G G G PG G+ G G G RG PG Sbjct: 470 LPGIDGRPGPIGP----AGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPD 525 Query: 2210 GNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPL 2269 GN G G PG +G QG +G QGP GP G GL G G +G G G G GE G GP Sbjct: 526 GNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPA 585 Query: 2270 GRKGEPGEP------GPKGGIGNRGPRGETGDDGRDG----------VGSEGRRGKKGER 2313 G +GE G P GP G IG+RGP G G DG G G G G GER Sbjct: 586 GPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGER 645 Query: 2314 GFPGYPGPKGNPGEPGLNGTTGPKGIRGRR------GNSGPPGIVGQKGDPGYPGPAGPK 2367 G G PG KG GEPGL G G G G R G GP G G +G+ G GPAGP Sbjct: 646 GAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPA 705 Query: 2368 GNRG 2371 G RG Sbjct: 706 GPRG 709 Score = 269 bits (688), Expect = 3e-71 Identities = 160/357 (44%), Positives = 185/357 (51%), Gaps = 30/357 (8%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGD------EGGPGERGPPGVNGTQGFQGCPGQR 2091 G+ GD+G G G +G PG DG G G +GG GE+GPPG GFQG PG Sbjct: 505 GKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPG---PPGFQGLPGPS 561 Query: 2092 GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPG---RRGDKGPRGEKGER 2148 G G G PGE+G GE GL G G G++G PG SG G G RG GP G G + Sbjct: 562 GPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNK 621 Query: 2149 GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208 G+ G+ G G G GP G G+ G G+PG G G PG G+ G GR G GA Sbjct: 622 GEPGVVGAVGTAGPS----GPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGA 677 Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGP------RGSGGAAGAPGE 2262 G G PG G G++G GA GPAGPAGP G GE+G GP G GAAG PG Sbjct: 678 PGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGA 737 Query: 2263 RGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGY---- 2318 +G G G KGE G GP G +G GP G G G GS G G G GFPG Sbjct: 738 KGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPG--PAGSRGDGGPPGMTGFPGAAGRT 795 Query: 2319 --PGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373 PGP G G PG G G +G+RG RG+ GP G G+ G G PG AG KG G++ Sbjct: 796 GPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEA 852 Score = 268 bits (686), Expect = 5e-71 Identities = 161/377 (42%), Positives = 189/377 (50%), Gaps = 44/377 (11%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGV------------NGTQGFQ 2085 G G GP G G G PG G++G G+ G PG+ GP G +G G Sbjct: 91 GPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKP 150 Query: 2086 GCPGQRGV---KGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDK--- 2139 G PG+RGV +G+RGFPG G G G+ G +G DG KG PG+ G KG PG G+ Sbjct: 151 GRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTP 210 Query: 2140 ---GPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGK 2196 G RG GERG VG G G G D GP G G +G G PG G PG GE G Sbjct: 211 GQTGARGLPGERGRVGAPGPAGARGSDGSV-GPVGPAGPIGSAGPPGFPGAPGPKGEIGA 269 Query: 2197 NGGFGRRGP---------PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGI 2247 G G GP PG G G PG PG G G +GA G G AG PGL G +GI Sbjct: 270 VGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGI 329 Query: 2248 SGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSE--- 2304 GP G+ GA GA G G GP G KGE G G G G +GP G +G++G+ G E Sbjct: 330 PGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGS 389 Query: 2305 -------GRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNS---GPPGIVGQ 2354 G RG G RG PG G G G PG G +GP G+RG G++ G PG++G Sbjct: 390 AGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGP 449 Query: 2355 KGDPGYPGPAGPKGNRG 2371 +G PG PG GP G G Sbjct: 450 RGLPGSPGNIGPAGKEG 466 Score = 264 bits (674), Expect = 1e-69 Identities = 172/451 (38%), Positives = 204/451 (45%), Gaps = 111/451 (24%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGE---------------RGPPGVNGT 2081 SG+ G RGP G G G PG G RG PG G PG GP GV G Sbjct: 375 SGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGP 434 Query: 2082 QGFQGCPGQRGVKGSRGFPGEKGEVGE------IGLDGLDGEDGDKGLPGSSGEKGNPGR 2135 G G PG+ G+ G RG PG G +G +GL G+DG G G G+ GE GN G Sbjct: 435 NGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGF 494 Query: 2136 RGDKGPRGEKGERGD------VGIRGDPGNPGQDSQE-----RGPKGETGDLGPMGVPGR 2184 G KGP G+ G+ GD G RG PG G + + +G +G G+ GP G PG Sbjct: 495 PGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGF 554 Query: 2185 DGVPGG---------PGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGP 2235 G+PG PGE G +G FG GP G +G +G PG+ G G G G++GP+GP Sbjct: 555 QGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGP 614 Query: 2236 AGPPGLIGEQGISGPRGSGGAAGA---PGERGRTGPLGRKGEPGEPGPKGGIGNRG---- 2288 GP G GE G+ G G+ G +G PGERG G G KGE GEPG +G IGN G Sbjct: 615 PGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGA 674 Query: 2289 -----------PRGETGDDGRDGV----------GSEGRRGKKGERGFPGYPGPKGNPGE 2327 P G TGD G G GS G RG+ G G G+ GP G G+ Sbjct: 675 RGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQ 734 Query: 2328 PGLNGT---------------TGPKGIRGRRGNSGPPGIVGQKGD--------------- 2357 PG G TGP G G G +GPPG G +GD Sbjct: 735 PGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGR 794 Query: 2358 ------------PGYPGPAGPKGNRGDSIDQ 2376 PG PGPAG +G RG DQ Sbjct: 795 TGPPGPSGISGPPGPPGPAGKEGLRGPRGDQ 825 Score = 263 bits (673), Expect = 2e-69 Identities = 154/354 (43%), Positives = 172/354 (48%), Gaps = 28/354 (7%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGT---------------- 2081 G GDRGP G GP G PG DG G G G PG GPPG+ G Sbjct: 33 GPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGP 92 Query: 2082 ---QGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGD 2138 G +G PG G G +GF G GE GE G G G G G PG +GE G+PG+ G Sbjct: 93 MGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGR 152 Query: 2139 KGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNG 2198 G RG G +G G G PG PG RG G G G G PG G PG PGE G G Sbjct: 153 PGERGVVGPQGARGFPGTPGLPGFKG-IRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPG 211 Query: 2199 GFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAG 2258 G RG PG +G G PG G G G+ G GPAGP G G G G GP+G GA G Sbjct: 212 QTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVG 271 Query: 2259 APGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGY 2318 G G GP G G PG GP G GN G G T G++G G G G PG Sbjct: 272 NAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLT--------GAKGAAGLPGVAGAPGL 323 Query: 2319 PGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 PGP+G PG G G TG +G+ G G +G G G KG+PG GP GP G G+ Sbjct: 324 PGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGE 377 Score = 262 bits (670), Expect = 3e-69 Identities = 160/390 (41%), Positives = 187/390 (47%), Gaps = 51/390 (13%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G+ G GP G+ GP G PG+ G G+PG G PGERG G G +GF G PG G KG R Sbjct: 121 GEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIR 180 Query: 2098 GF------------PGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPG---RRGDKGPR 2142 G PG KGE G G +G G+ G +GLPG G G PG RG G Sbjct: 181 GHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSV 240 Query: 2143 GEKGERGDVGIRGDPGNPGQDSQE--------------RGPKGE---------------- 2172 G G G +G G PG PG + GP+GE Sbjct: 241 GPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNP 300 Query: 2173 -----TGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTR 2227 TG G G+PG G PG PG G G G G GA+G G PG G +GE G + Sbjct: 301 GANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNK 360 Query: 2228 GAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNR 2287 G G AGP GPPG GE+G GP G G+AG PG G G G +G PG G G +G Sbjct: 361 GEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPP 420 Query: 2288 GPRGETGDDG-RDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNS 2346 G RG +G G R G GR G+ G G G PG GN G G G G GI GR G Sbjct: 421 GSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPI 480 Query: 2347 GPPGIVGQKGDPGYPGPAGPKGNRGDSIDQ 2376 GP G G+ G+ G+PGP GP G+ G + D+ Sbjct: 481 GPAGARGEPGNIGFPGPKGPTGDPGKNGDK 510 Score = 262 bits (669), Expect = 5e-69 Identities = 162/380 (42%), Positives = 187/380 (49%), Gaps = 42/380 (11%) Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQ 2085 E+ G P G G RG GS+GP G G G G PG G PG +G G G G Sbjct: 221 ERGRVGAP----GPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPA 276 Query: 2086 GCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEK 2145 G G RG G G G G G G +GL G G GLPG +G G PG RG GP G Sbjct: 277 GPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAA 336 Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP 2205 G G G+ G+PG P E G KGE G GP G PG G G G G+ G G GP Sbjct: 337 GATGARGLVGEPG-PAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGP 395 Query: 2206 PGAKGNKGGPGQPGFEGEQG------TRGAQGPAGPAGP---------PGLIGEQGISG- 2249 PG +G+ G G PG +G G +RGA GPAG GP PGL+G +G+ G Sbjct: 396 PGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGS 455 Query: 2250 -----PRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG---- 2300 P G G G PG GR GP+G G GEP G IG GP+G TGD G++G Sbjct: 456 PGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEP---GNIGFPGPKGPTGDPGKNGDKGH 512 Query: 2301 ---VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGD 2357 G+ G G G G G PGP+G G G G GP G +G G SGP G VG+ G+ Sbjct: 513 AGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGE 572 Query: 2358 P------GYPGPAGPKGNRG 2371 G PGPAGP+G RG Sbjct: 573 RGLHGEFGLPGPAGPRGERG 592 Score = 260 bits (665), Expect = 1e-68 Identities = 161/408 (39%), Positives = 194/408 (47%), Gaps = 72/408 (17%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKG-- 2095 G+RG GP G+ G G PG G++G G G G +G PG G +G G PG+ G G Sbjct: 154 GERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQT 213 Query: 2096 -SRGFPGEKGEVGEIGLDGLDGEDGD---------------KGLPGSSGEKGNPGRRGDK 2139 +RG PGE+G VG G G G DG G PG+ G KG G G+ Sbjct: 214 GARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNA 273 Query: 2140 GPRGEKGERGDVGIRG------DPGNPGQDSQER-----------------GPKGETGDL 2176 GP G G RG+VG+ G PGNPG + GP+G G + Sbjct: 274 GPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPV 333 Query: 2177 GPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPA 2236 G G G G+ G PG G G G +G PG+ G +G PG G EG++G G G AGP Sbjct: 334 GAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPP 393 Query: 2237 GPPGLIGEQG------------ISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKG-- 2282 GPPGL G G + GP GS GA+G G RG G GR GEPG GP+G Sbjct: 394 GPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLP 453 Query: 2283 -------GIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGE------- 2327 G GP G G DGR G +G G RG+ G GFPG GP G+PG+ Sbjct: 454 GSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHA 513 Query: 2328 --PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373 G G GP G G +G GP G+ G KG+ G PGP G +G G S Sbjct: 514 GLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPS 561 Score = 254 bits (650), Expect = 7e-67 Identities = 153/358 (42%), Positives = 179/358 (50%), Gaps = 21/358 (5%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRG 2092 P +G G GP G G +G G G G+PG G G GP G++G G G G+ G Sbjct: 758 PVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEG 817 Query: 2093 VKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVG 2152 ++G RG G G GE+G G G G+KG G +G G PG G +G G G G G Sbjct: 818 LRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPG 877 Query: 2153 IRGDPGNPGQDSQ--ERGP---KGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPG 2207 RG+ G PG E GP G G GP G G GV G PGE G++G G GPPG Sbjct: 878 SRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPG 937 Query: 2208 AKG---NKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERG 2264 G +KG G PG G G GA GP GP GP G G +G +GP G G AGA G RG Sbjct: 938 RDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRG 997 Query: 2265 RTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-------GSEGRRGKKGERGFPG 2317 +GP G +G+ GEPG KG G G +G G G G+ G+ G G G RG G Sbjct: 998 PSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAG 1057 Query: 2318 YPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSID 2375 GP G G G GT GP GIRG +G+ GP G PG PGP GP G G D Sbjct: 1058 PSGPAGKDGRTGHPGTVGPAGIRGPQGHQGP------AGPPGPPGPPGPPGVSGGGYD 1109 Score = 214 bits (546), Expect = 8e-55 Identities = 134/312 (42%), Positives = 151/312 (48%), Gaps = 34/312 (10%) Query: 2094 KGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGD-------------KG 2140 KG G G +GE G G G DGEDG G PG G G PG G+ G Sbjct: 32 KGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPG 91 Query: 2141 PRGEKGERGDVGIRGDPG-----NPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETG 2195 P G G RG G G PG P + E G G G GP G PG+ G G PG+ G Sbjct: 92 PMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPG 151 Query: 2196 KNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGG 2255 + G G GP GA+G G PG PGF+G +G G G G G PG+ GE G G G+ G Sbjct: 152 RPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPG 211 Query: 2256 AAGA---PGERGRT---GPLGRKGEPGE---PGPKGGIGNRGPRGETGDDGRDG------ 2300 GA PGERGR GP G +G G GP G IG+ GP G G G G Sbjct: 212 QTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVG 271 Query: 2301 -VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPG 2359 G G G +GE G PG GP G PG PG NG TG KG G G +G PG+ G +G PG Sbjct: 272 NAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPG 331 Query: 2360 YPGPAGPKGNRG 2371 G AG G RG Sbjct: 332 PVGAAGATGARG 343 Score = 198 bits (503), Expect = 8e-50 Identities = 117/272 (43%), Positives = 137/272 (50%), Gaps = 8/272 (2%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096 +G++G G G+ GP G PG G G PG G PG RG G+ G G G PG G+ G Sbjct: 843 AGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGP 902 Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGD 2156 G G G VG G++G GE G G PG+ G G G+ G KG RG G G VG G Sbjct: 903 PGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGA 962 Query: 2157 PG--NPGQDSQERGPKGETGDLGPMGVPGRDGV--PGGP----GETGKNGGFGRRGPPGA 2208 PG P + + G +GETG GP+G G G P GP G+ G+ G G RG PG Sbjct: 963 PGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGL 1022 Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2268 KG+ G G PG G G +GA G GPAGP G G G +G G G G G G GP Sbjct: 1023 KGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGP 1082 Query: 2269 LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG 2300 G +G G PGP G G G G D G DG Sbjct: 1083 QGHQGPAGPPGPPGPPGPPGVSGGGYDFGYDG 1114 Score = 165 bits (418), Expect = 6e-40 Identities = 97/226 (42%), Positives = 113/226 (50%), Gaps = 14/226 (6%) Query: 2162 QDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGN-------KG- 2213 +++ +GP G+ G G G PG G G G TG G G GPPG GN KG Sbjct: 27 EETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGV 86 Query: 2214 --GPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGR 2271 GPG G G +G GA G GP G G GE G G G GA G G G+ G G Sbjct: 87 GLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGH 146 Query: 2272 KGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGL 2330 G+PG PG +G +G +G RG G G G G G G G +G PG PG KG PG PG Sbjct: 147 PGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGE 206 Query: 2331 NGT---TGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373 NGT TG +G+ G RG G PG G +G G GP GP G G + Sbjct: 207 NGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSA 252 Score = 164 bits (414), Expect = 2e-39 Identities = 98/239 (41%), Positives = 113/239 (47%), Gaps = 4/239 (1%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096 +G G+ GP+G GP G G G G PG G PGE G G G G G GQ G KG Sbjct: 888 AGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGE 947 Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGD 2156 RG+PG G VG G G G G G G+ GE G G G G G +G G GIRGD Sbjct: 948 RGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGD 1007 Query: 2157 PGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPG 2216 G PG E+GP+G G G G+ G G+ G G+ G G G GP G G G G Sbjct: 1008 KGEPG----EKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAG 1063 Query: 2217 QPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEP 2275 + G G GT G G GP G G G G GP G G +G + G G R +P Sbjct: 1064 KDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSGGGYDFGYDGDFYRADQP 1122 Score = 79.7 bits (195), Expect = 4e-14 Identities = 49/127 (38%), Positives = 58/127 (45%), Gaps = 12/127 (9%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRG 2092 P G RGD+G G GP+G+PG G+ G +G PG+ G G QG PG G Sbjct: 998 PSGPQGIRGDKGEPGEKGPRGLPGLKGHNGL---------QGLPGIAGHHGDQGAPGSVG 1048 Query: 2093 VKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERG--- 2149 G RG G G G+ G G G G G+ G G +G G G GP G G G Sbjct: 1049 PAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSGGGY 1108 Query: 2150 DVGIRGD 2156 D G GD Sbjct: 1109 DFGYDGD 1115 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 277 bits (708), Expect = 1e-73 Identities = 160/356 (44%), Positives = 193/356 (54%), Gaps = 38/356 (10%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G GDRGPIG G G PG+ G PG++G PG GPPG G +G G G++G +G Sbjct: 1589 GDPGDRGPIGLTGRAGPPGDSGP---PGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPP 1645 Query: 2098 GFPGEKGEVGEIGLDGLD------GEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDV 2151 G PG G+ GE GL G GE GD+G PG G G+PG G KG RGE G G Sbjct: 1646 GDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPP 1705 Query: 2152 G----------IRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFG 2201 G +G+PG+ GQ+ GP+G GD G G PG G+ G G G G G Sbjct: 1706 GRLVDTGPGAREKGEPGDRGQE----GPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPG 1761 Query: 2202 RRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGP------------PGLIGEQGISG 2249 RGP G KG++G PG G G G GA GP+GP G PGL GEQG+ G Sbjct: 1762 VRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPG 1821 Query: 2250 PRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRG 2308 P G G G PGE G+ G G+ GEPG+PG G G +G G +G +GRDG G G G Sbjct: 1822 PSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPG 1881 Query: 2309 KKGERGFPGYPGPKGNPGE--PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPG 2362 G +G PG PGP G PG+ PG+ G TGPKG RG G+ G G+ G++G G PG Sbjct: 1882 ILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPG 1937 Score = 276 bits (707), Expect = 2e-73 Identities = 167/373 (44%), Positives = 204/373 (54%), Gaps = 44/373 (11%) Query: 2038 GQRGDRGPIGSIGPKGIPG--EDGYRGYPGDEGGPGE---RGPPGVNGTQGFQGCPG--- 2089 G G +GP+G G KG G EDG G PG G PGE RGPPG G +G +G PG Sbjct: 1430 GSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLG 1489 Query: 2090 QRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSG---EKGNPGRRGDK------- 2139 + G KG RG PG G G G+ G G G +G PG +G EKG PGR GD Sbjct: 1490 EAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAV 1549 Query: 2140 -GPRGEKGE------RGDVGIRGDPGNPGQDSQ-ERGPKGETGDLGPMGVPGRDGVPGGP 2191 GP+GEKG+ RG G++G+ G PG + GPKG+ GD GP+G+ GR G PG Sbjct: 1550 AGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDS 1609 Query: 2192 GETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPR 2251 G G+ G GR GPPG G +G G+ G +G++G G G G AG GL G G+ GP Sbjct: 1610 GPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPV 1669 Query: 2252 GSGGAAGAPGERGR------TGPLGRKGEPGEPGPKGGIGNRGP----RGETGDDGRDGV 2301 G G G PGE GR +GP G +GEPG PGP G + + GP +GE GD G+ Sbjct: 1670 GEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQ--- 1726 Query: 2302 GSEGRRGKKGERGFPGYPGPKGNP---GEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDP 2358 EG RG KG+ G PG PG +G G PG G G +G G +G+ GPPG+ G+ G Sbjct: 1727 --EGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLD 1784 Query: 2359 GYPGPAGPKGNRG 2371 G PG AGP G G Sbjct: 1785 GKPGAAGPSGPNG 1797 Score = 274 bits (700), Expect = 1e-72 Identities = 167/401 (41%), Positives = 206/401 (51%), Gaps = 68/401 (16%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G++G RGP G+IGPKG + G+ G G+ G GERGPPG G++G G G+ G KG Sbjct: 1465 GEQGPRGPPGAIGPKG---DRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPE 1521 Query: 2098 GFPG------EKGEVGEIG--------LDGLDGEDGD------KGLPGSSGEKGNPGR-- 2135 G PG EKGE G G + G GE GD +G G GE+G PG Sbjct: 1522 GPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVL 1581 Query: 2136 RGDKGPRGEKGERGDVGI---------------RGDPGNPGQDSQ--ERGPKGETGDLGP 2178 GD GP+G+ G+RG +G+ +GDPG PG RG GE G+ G Sbjct: 1582 PGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGD 1641 Query: 2179 MGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQ------PGFEGEQGTRGAQGP 2232 G PG G+PG GE G G G RGP G KG++G PG+ PG G +G RG GP Sbjct: 1642 EGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGP 1701 Query: 2233 AGPAG-------------PPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPG 2279 GP G PG G++G GP+G G GAPGERG G G G G+PG Sbjct: 1702 PGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPG 1761 Query: 2280 PKGGIGNRGPRGETGDDGRDGV-------GSEGRRGKKGERGFPGYPGPKGNPGEPGLNG 2332 +G G +G RG G DGR G+ G G G G+ G PG G G GE GL G Sbjct: 1762 VRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPG 1821 Query: 2333 TTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373 +GP G+ G+ G G PG+ G+ G+PG PG G KG +GDS Sbjct: 1822 PSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDS 1862 Score = 271 bits (692), Expect = 1e-71 Identities = 166/411 (40%), Positives = 205/411 (49%), Gaps = 69/411 (16%) Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQ 2090 GVP G G G G +G G+PG G G+PG G GE G PG +G +G G PG+ Sbjct: 2374 GVPGS-PGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGR 2432 Query: 2091 RGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKG--LPGSSGEKGNPGRRGDKG-------- 2140 G+ G G PG G VG G GL G+ GD G LPG GE+G PG RG+ G Sbjct: 2433 EGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPR 2492 Query: 2141 -------PRGEKGERGDVG---IRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGG 2190 RGE+GE+GDVG ++GD G+ GP+G GD+G G G DG G Sbjct: 2493 GLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGP 2552 Query: 2191 PGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQG-PAGPAGP-----PGLIGE 2244 G+ G G G +G PG KG+ G PG G G QG GA G P P P PG+ GE Sbjct: 2553 RGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGE 2612 Query: 2245 QG---ISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV 2301 +G GPRG G G G G G G KGE G PG G G++G GE G G+ G Sbjct: 2613 KGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGA 2672 Query: 2302 -GSEGRRGKKGERGFPGYPGPKGN---------------------------PGEPGLNGT 2333 G EG G KG+RGF G PGPKG+ PG PG G Sbjct: 2673 PGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGP 2732 Query: 2334 TGPKGIRGRRGNSGP-----------PGIVGQKGDPGYPGPAGPKGNRGDS 2373 GP+G++G++G GP PG G++G+ G PGPAGP+G +G++ Sbjct: 2733 RGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEA 2783 Score = 266 bits (681), Expect = 2e-70 Identities = 177/397 (44%), Positives = 201/397 (50%), Gaps = 67/397 (16%) Query: 2030 CGVPCKCSGQRGDRGPIG---SIGPKGIPGEDGYRGYPGDEGGPG------ERGPPGVNG 2080 C V C GQ+G+ G +G +GP G PG G G PG +G PG ERG PG +G Sbjct: 1247 CPVYCP-KGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADG 1305 Query: 2081 TQGFQG------CPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPG 2134 G G PG G+KGS G PG +G+ GE G G GE G G G PG Sbjct: 1306 RPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPG 1365 Query: 2135 RRGDKGPRGEKGER---GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGV---- 2187 R+GD GP G G R GD G RG PG PG + +G KG+ G+ GP G PG G+ Sbjct: 1366 RKGDPGPSGPPGPRGPLGDPGPRGPPGLPG--TAMKGDKGDRGERGPPG-PGEGGIAPGE 1422 Query: 2188 PGGPGETGKNGGFGRRGPPGAKGNKGG--------PGQPGFEGEQGTRGAQGPAGP---- 2235 PG PG G G G GPPG KG KG PGQPG GEQG RG G GP Sbjct: 1423 PGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDR 1482 Query: 2236 --AGPPGLIGEQGISGPRGSGGAAGAPGERGR---------TGPLGRKGEPGEPGPKG-- 2282 GP G GE+G GP G G+ G PG GR GP GR+GE GEPG G Sbjct: 1483 GFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDP 1542 Query: 2283 ---GIGNRGPRGETGDDGRDGVGSEGRRGKKGERG-----FPGYPGPKGNPGEPGLNGTT 2334 G GP+GE GD G G G G +GERG PG PGPKG+PG+ Sbjct: 1543 AVVGPAVAGPKGEKGDVG--PAGPRGATGVQGERGPPGLVLPGDPGPKGDPGD------R 1594 Query: 2335 GPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 GP G+ GR G G G G+KGDPG PGP GP G RG Sbjct: 1595 GPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRG 1631 Score = 266 bits (680), Expect = 2e-70 Identities = 170/413 (41%), Positives = 196/413 (47%), Gaps = 79/413 (19%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGIP---------------------GEDGYRGYPGDEGGPG 2071 P G G GP G +GP+G P G+DG RG PG G PG Sbjct: 2222 PTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPG 2281 Query: 2072 ERGPPGVNGTQGFQGCPGQR-------------------------GVKGSRGFP---GEK 2103 GP G G G G PGQ G KG RG P GEK Sbjct: 2282 LPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEK 2341 Query: 2104 GEVGEIGLDGLDGEDGDKGLPGSSGEKGNP--GRRGDKGPRGEKGERGDVGIRGDPGNPG 2161 GE G G G GEDG KG PG G KG+P G G GP G G +GD+G+ G PG PG Sbjct: 2342 GEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPG 2401 Query: 2162 QDS--QERGPKGETGDLGP------MGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKG 2213 + GP+GE G GP G PGR+G+PG G G G G G G KG+KG Sbjct: 2402 VVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKG 2461 Query: 2214 GP-----------GQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE 2262 P G+PG GE G G +GP G GPPG GE+G G GS G G G+ Sbjct: 2462 DPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGD 2521 Query: 2263 R----GRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGY 2318 G GP G KG+ GE GP+G G++GPRG+ GD G GS+G G KG G PG Sbjct: 2522 SAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPG--DKGSKGEPGDKGSAGLPGL 2579 Query: 2319 PGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 G G G+PG G G G G+ G PGI G+KGD G+ GP G KG RG Sbjct: 2580 RGLLGPQGQPGAAGIPGDPGSPGK---DGVPGIRGEKGDVGFMGPRGLKGERG 2629 Score = 266 bits (679), Expect = 3e-70 Identities = 177/428 (41%), Positives = 216/428 (50%), Gaps = 90/428 (21%) Query: 2031 GVPCKCSGQRGDRGPIGSI---GPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGF--- 2084 G+P + +G G +GP GS G +G PG DG G PG G PG G PG+ G+ G Sbjct: 1275 GLPGR-TGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGP 1333 Query: 2085 QGCPGQRGVKGSRGFPGEKGEV--GE-IGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGP 2141 +G PG+RG +G +G PG G+V GE GL G G+ G G PG G G+PG RG G Sbjct: 1334 RGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGL 1393 Query: 2142 RGE--KGERGDVGIRGDPGNPGQDSQERGPKG------ETGDLGPMGVPGR--------D 2185 G KG++GD G RG PG PG+ G G G GP+G PG+ D Sbjct: 1394 PGTAMKGDKGDRGERGPPG-PGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSED 1452 Query: 2186 GVPGGPGETGKNGGFGRRGPPGA---KGNKGGPGQPGFEGEQGTRGAQGPAG-------- 2234 G PG PG+ G G G RGPPGA KG++G PG G GE+G RG GPAG Sbjct: 1453 GAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVA 1512 Query: 2235 -------PAGPPGLIGEQG-----------------ISGPRGSGGAAGAPGERGRTGPLG 2270 P GPPG G QG ++GP+G G G G RG TG G Sbjct: 1513 GRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQG 1572 Query: 2271 RKGEPG-----EPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGP---- 2321 +G PG +PGPKG G+RGP G TG G G G G+KG+ G PG PGP Sbjct: 1573 ERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPG--DSGPPGEKGDPGRPGPPGPVGPR 1630 Query: 2322 -----------KGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDP------GYPGPA 2364 +G PG+PGL G G +G+RG G GP G G +GDP G PG + Sbjct: 1631 GRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSS 1690 Query: 2365 GPKGNRGD 2372 GPKG+RG+ Sbjct: 1691 GPKGDRGE 1698 Score = 265 bits (676), Expect = 7e-70 Identities = 163/376 (43%), Positives = 186/376 (49%), Gaps = 40/376 (10%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G G G +G G G PG DG G GD G PG G PG+ G G +G PG G G Sbjct: 2242 GSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQA 2301 Query: 2098 --GFPGEKGEVGEIG-----LDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD 2150 G PG KGE G G L G G GD+GLPG GEKG GR G+ G GE G++G Sbjct: 2302 VVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGA 2361 Query: 2151 VGIRGDPGNPGQ----DSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPP 2206 G +G G+PG GP G GDLG G+PG GV G PG+TG G G+ GP Sbjct: 2362 PGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPS 2421 Query: 2207 GAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQG-----ISGPRGSGGAAGAPG 2261 G +G G PG+ G G G G G GP G GL G++G + GPRG G G G Sbjct: 2422 GERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRG 2481 Query: 2262 ERGR---------TGPLGRKGEPGEPGPKGGIGNRG-------------PRGETGDDGRD 2299 E GR TGP G +GE GE G G G +G PRG GD G Sbjct: 2482 EDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGER 2541 Query: 2300 GVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPG 2359 G G G KG RG G PG KG+ GEPG G+ G G+RG G G PG G GDPG Sbjct: 2542 G--PRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPG 2599 Query: 2360 YPGPAGPKGNRGDSID 2375 PG G G RG+ D Sbjct: 2600 SPGKDGVPGIRGEKGD 2615 Score = 265 bits (676), Expect = 7e-70 Identities = 165/380 (43%), Positives = 196/380 (51%), Gaps = 46/380 (12%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGER--GPPGVNGTQGFQG-----CPG 2089 SG+ GDRG G G G+PG G +G PG G PG+ G PG G +G G G Sbjct: 2265 SGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVG 2324 Query: 2090 QRGVKGSRGFPG---EKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRR--GDKGPRGE 2144 + G KG RG PG EKGE G G G GEDG KG PG G KG+PG G GP G Sbjct: 2325 EPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGP 2384 Query: 2145 KGERGDVGIRGDPGNPGQDS--QERGPKGETGDLGPMGV------PGRDGVPGGPGETGK 2196 G +GD+G+ G PG PG + GP+GE G GP G PGR+G+PG G G Sbjct: 2385 PGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGP 2444 Query: 2197 NGGFGRRGPPGAKGNKGGPG-----------QPGFEGEQGTRGAQGPAGPAGPPGLIGEQ 2245 G G G G KG+KG PG +PG GE G G +GP G GPPG GE+ Sbjct: 2445 PGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGER 2504 Query: 2246 GISGPRGSGGAAGAPGER----GRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV 2301 G G GS G G G+ G GP G KG+ GE GP+G G++GPRG+ GD G G Sbjct: 2505 GEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKG- 2563 Query: 2302 GSEGRRGKKGERGFPGYPG---PKGNPGE---PGLNGTTGPKGIRGRRGNSGPPGIVGQ- 2354 S+G G KG G PG G P+G PG PG G+ G G+ G RG G G +G Sbjct: 2564 -SKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPR 2622 Query: 2355 --KGDPGYPGPAGPKGNRGD 2372 KG+ G G G G +GD Sbjct: 2623 GLKGERGVKGACGLDGEKGD 2642 Score = 262 bits (670), Expect = 3e-69 Identities = 161/383 (42%), Positives = 190/383 (49%), Gaps = 49/383 (12%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPG-----DEGGPG---ERGPPGVNGTQGFQGCPG 2089 G++G+RG G GP G+PG G G PG DE GPG E+GPPG+ G +G G G Sbjct: 2064 GEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNG 2123 Query: 2090 QRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERG 2149 +G KG RG PG KG+ GE G G DG G G G +G +G PG +G +GP G G G Sbjct: 2124 DQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHG 2183 Query: 2150 DVGIRGDPG--NPGQDSQERGPKGETGDLGP-----------------------MGVPGR 2184 D G G PG P G KGE G+ GP +G G Sbjct: 2184 DPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGS 2243 Query: 2185 DGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPG--LI 2242 G+PG GETGK G GR G G G++G PG PG G G G +G GP G PG ++ Sbjct: 2244 PGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVV 2303 Query: 2243 GEQGISGPRGS-GGAAG-------------APGERGRTGPLGRKGEPGEPGPKGGIGNRG 2288 G G G +G+ GG AG PG RG G GR GEPG+PG G G G Sbjct: 2304 GLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPG 2363 Query: 2289 PRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGP 2348 P+G GD G GS G G G +G G PG G PG G G TGP+G G+ G SG Sbjct: 2364 PKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGE 2423 Query: 2349 PGIVGQKGDPGYPGPAGPKGNRG 2371 G+ G G G PGP GP G G Sbjct: 2424 RGLAGPPGREGIPGPLGPPGPPG 2446 Score = 260 bits (665), Expect = 1e-68 Identities = 160/366 (43%), Positives = 184/366 (50%), Gaps = 39/366 (10%) Query: 2038 GQRGDRGPIGS---IGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094 G GD GP G+ GP G G G +G PG+ G PG RG G G G G PG G+ Sbjct: 2180 GGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPG-RGLTGPTGAVGLPGPPGPSGLV 2238 Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154 G +G PG G+VGE G G G DG G G G G PG G GP G KGE G G Sbjct: 2239 GPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAP 2298 Query: 2155 GDP--GNPGQDSQERGPKGETGDL-GPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGN 2211 G G PG ++ P G GDL G G G G+PG GE G+ G G G PG G Sbjct: 2299 GQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQ 2358 Query: 2212 KGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGI---------------SGPRGSGGA 2256 KG PG GF+G+ G G G GP GPPG+ G+ G+ +GPRG G Sbjct: 2359 KGAPGPKGFKGDPGV-GVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQ 2417 Query: 2257 AGAPGERGRTGPLGRKGEPGE---PGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGER 2313 G GERG GP GR+G PG PGP G +G G G GD G GVG G RG++GE Sbjct: 2418 PGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGE- 2476 Query: 2314 GFPGYPGPKGN---PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPG----YPGPAGP 2366 PG +G PG+ G G TGP G RG RG G G G KGD G GP GP Sbjct: 2477 -----PGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGP 2531 Query: 2367 KGNRGD 2372 +G +GD Sbjct: 2532 RGAKGD 2537 Score = 259 bits (661), Expect = 4e-68 Identities = 169/439 (38%), Positives = 208/439 (47%), Gaps = 104/439 (23%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096 +G++GDRGP G G G+ G+ G G G G G+ G PG +G G +G G G G Sbjct: 1766 AGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGP 1825 Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPG---RRGDKGPRGEKGERGDVGI 2153 G PG+ GE G+ GL+G +GE GD G G GEKG+ G R G GP+GE+G G +G Sbjct: 1826 PGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGP 1885 Query: 2154 RGDPGNPGQ-------------DSQERGPKGETGDLGPMGVPGRDGVPGGPG-------- 2192 +G PG PG + +G +GETG G G+PG G+ G PG Sbjct: 1886 QGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRL 1945 Query: 2193 -ETG----------------KNGGF-----GRRGPPGAKGNKGGPGQP---GFEGEQGTR 2227 ET +G F RRGP G G +G PG+ GF GE+G + Sbjct: 1946 LETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLK 2005 Query: 2228 GAQGPAGPAGPPGL-IGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGN 2286 G +G GP GPPGL +GE+G GP G G G PG G G G GE G PG +G G Sbjct: 2006 GDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGE 2065 Query: 2287 RGPRGETGDDGRDGV---------------------------------------GSEGRR 2307 +G RGE G DG G+ GS G + Sbjct: 2066 KGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQ 2125 Query: 2308 GKKGERGFPGY------PGPK---GNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDP 2358 G KG+RG PG PGP+ GNPG PG G GP+G G +G GPPG VG GDP Sbjct: 2126 GPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDP 2185 Query: 2359 GYP------GPAGPKGNRG 2371 G P GPAGP+G G Sbjct: 2186 GPPGAPGLAGPAGPQGPSG 2204 Score = 259 bits (661), Expect = 4e-68 Identities = 165/382 (43%), Positives = 188/382 (49%), Gaps = 66/382 (17%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGV----------------NGT 2081 G G++GP G GP G PGE RG GD G PG +GPPG+ G Sbjct: 1982 GDSGEQGPPGKEGPIGFPGE---RGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGK 2038 Query: 2082 QGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRR----- 2136 G G PG+ G G G PGE+GE GE G G G DG GLPG+ G G PG + Sbjct: 2039 PGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDE 2098 Query: 2137 ------GDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGG 2190 G++GP G KG +G+ G GD G G +RG G GD G G G+DG PG Sbjct: 2099 PGPGLSGEQGPPGLKGAKGEPGSNGDQGPKG----DRGVPGIKGDRGEPGPRGQDGNPGL 2154 Query: 2191 PGE------TGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGE 2244 PGE GK G G RGPPG G G PG P G G GPAGP GP GL GE Sbjct: 2155 PGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPP------GAPGLAGPAGPQGPSGLKGE 2208 Query: 2245 QGISGPRGSG-----GAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRD 2299 G +GP G G GA G PG G +G +G +G PG PG G G G G G G+D Sbjct: 2209 PGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKD 2268 Query: 2300 GVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPK--GIRGRRGNSGPPG-----IV 2352 G RG G G PG PGP G GEPG G G G+ G +G G PG +V Sbjct: 2269 -----GDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLV 2323 Query: 2353 GQ---KGDPGYPGPAGPKGNRG 2371 G+ KGD G PGP G KG G Sbjct: 2324 GEPGAKGDRGLPGPRGEKGEAG 2345 Score = 258 bits (658), Expect = 9e-68 Identities = 165/401 (41%), Positives = 189/401 (47%), Gaps = 82/401 (20%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGD------------------------------ 2066 +G +GDRG GS G +G+PGE G RG PG Sbjct: 1909 TGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSG 1968 Query: 2067 ------------EGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPG----------EKG 2104 +G GE+GPPG G GF PG+RG+KG RG PG E+G Sbjct: 1969 SFLPVPERRRGPKGDSGEQGPPGKEGPIGF---PGERGLKGDRGDPGPQGPPGLALGERG 2025 Query: 2105 EVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDS 2164 G GL G G+ G GLPG +G G GR G++G RGEKGERG+ G G PG PG Sbjct: 2026 PPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPG 2085 Query: 2165 QER--GPKGETGDLGP-----MGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQ 2217 GPK + GP G PG G G PG G G G RG PG KG++G PG Sbjct: 2086 PPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGP 2145 Query: 2218 PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGR------ 2271 G +G G G +G AGP G PGL G +G GP G G G PG G GP G Sbjct: 2146 RGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGL 2205 Query: 2272 KGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGL 2330 KGEPGE GP G RG TG G G+ G G G G +G PG PG G G+PG Sbjct: 2206 KGEPGETGPPG-------RGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGA 2258 Query: 2331 NGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 G G G G RG+ G P G PG PGP GPKG G Sbjct: 2259 PGRDGASGKDGDRGSPGVP------GSPGLPGPVGPKGEPG 2293 Score = 256 bits (654), Expect = 2e-67 Identities = 162/408 (39%), Positives = 188/408 (46%), Gaps = 73/408 (17%) Query: 2031 GVPCKCSGQRGDRGP------------------IGSIGPKGIPGEDGYRGYPGDEGGPGE 2072 G P G+RG GP G +G G PGE G RG G+ G G Sbjct: 2015 GPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGR 2074 Query: 2073 RGPPGVNGTQGFQGCPGQR--------GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLP 2124 GPPG+ GT G G PG + G+ G +G PG KG GE G +G G GD+G+P Sbjct: 2075 DGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVP 2134 Query: 2125 GSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPG--------NPGQDSQERGPKGETGDL 2176 G G++G PG RG G G GERG G G PG P + GP G G Sbjct: 2135 GIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLA 2194 Query: 2177 GPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPA 2236 GP G G G+ G PGETG G G GP GA G G PG G G QG+ G G G Sbjct: 2195 GPAGPQGPSGLKGEPGETGPPGR-GLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGET 2253 Query: 2237 GPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEP--------------------- 2275 G PG G G SG G G+ G PG G GP+G KGEP Sbjct: 2254 GKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKG 2313 Query: 2276 ----------GEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNP 2325 GEPG KG G GPRGE G+ GR G G GE G G PGPKG Sbjct: 2314 APGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGR-----AGEPGDPGEDGQKGAPGPKGFK 2368 Query: 2326 GEPGLN--GTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 G+PG+ G+ GP G G +G+ G PG+ G G G+PG GP+G G Sbjct: 2369 GDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMG 2416 Score = 256 bits (653), Expect = 3e-67 Identities = 165/397 (41%), Positives = 191/397 (48%), Gaps = 58/397 (14%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPG-EDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQR 2091 P G+RG +G G GP+G PG G RG PG G GE G PG+ G G G G+ Sbjct: 1995 PIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEA 2054 Query: 2092 GVKGSRGFPGEKGEVGEIGLDGL-----------------------DGEDGDKGLPGSSG 2128 G G RG GEKGE GE G DG G G++G PG G Sbjct: 2055 GRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKG 2114 Query: 2129 EKGNPGRRGDKGPRGE------KGERGDVGIRGDPGNPGQDSQE--RGPKGETGDLGPMG 2180 KG PG GD+GP+G+ KG+RG+ G RG GNPG + GP+G+ G GP G Sbjct: 2115 AKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRG 2174 Query: 2181 VP---GRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAG 2237 P G G PG PG G G G +GP G KG G G PG G G GA G GP G Sbjct: 2175 PPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPG-RGLTGPTGAVGLPGPPG 2233 Query: 2238 PPGLIGEQ---GISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETG 2294 P GL+G Q G+ G G G GAPG G +G G +G PG PG G G GP+GE G Sbjct: 2234 PSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPG 2293 Query: 2295 DDGRDGVGSEGRRGKKGERGFP-----------------GYPGPKGNPGEPGLNGTTGPK 2337 G G G G KGE+G P G PGP+G GE G G G Sbjct: 2294 PTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDP 2353 Query: 2338 GIRGRRGNSGPPGIVGQK--GDPGYPGPAGPKGNRGD 2372 G G++G GP G G G PG PGP GP G +GD Sbjct: 2354 GEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGD 2390 Score = 249 bits (635), Expect = 4e-65 Identities = 166/458 (36%), Positives = 196/458 (42%), Gaps = 121/458 (26%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097 G++GD GP G G G GE G RG PG G GE+G G G G G PG G KG R Sbjct: 1637 GEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDR 1696 Query: 2098 GFPG----------------EKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGP 2141 G PG EKGE G+ G +G G GD GLPG+ GE+G G RG GP Sbjct: 1697 GEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGP 1756 Query: 2142 RGEKGERGDVGIRGDPGNPGQDSQE--------RGPKGETGDLGPMGVPGRDGVPG---- 2189 +G+ G RG G +GD G PG D + GP G G G G PGRDG+PG Sbjct: 1757 QGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGE 1816 Query: 2190 --------------GPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGP 2235 PGE GK G G+ G PG G G G+ G G G G GP G Sbjct: 1817 QGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGE 1876 Query: 2236 AGPPGLIGEQGISG------PRGSG-----GAAGAPGERGRTGPLGRKGEPGEPGPKGGI 2284 G PG++G QG G P G G G G G+RG TG G +G PGE G +G Sbjct: 1877 RGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEP 1936 Query: 2285 GN---------------------------------------RGPRGETGDDGRDG----V 2301 G+ RGP+G++G+ G G + Sbjct: 1937 GSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPI 1996 Query: 2302 GSEGRRGKKGERGFPGYPGPKG----------------NPGEPGLNGT---------TGP 2336 G G RG KG+RG PG GP G PG+PG+ G G Sbjct: 1997 GFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGR 2056 Query: 2337 KGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSI 2374 G RG RG G G G+ G PG PG GP G G + Sbjct: 2057 PGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKV 2094 Score = 241 bits (614), Expect = 1e-62 Identities = 159/411 (38%), Positives = 186/411 (45%), Gaps = 73/411 (17%) Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQ 2090 G+P K +G+RG RG G GP G G+ G G G G PG GP G G G G PG+ Sbjct: 1649 GLPGK-AGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGR 1707 Query: 2091 RGVKGSRGFPG--EKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER 2148 G PG EKGE G+ G +G G GD GLPG+ GE+G G RG GP+G+ G R Sbjct: 1708 LVDTG----PGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVR 1763 Query: 2149 GDVGIRGDPGNPGQDSQE--------RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGF 2200 G G +GD G PG D + GP G G G G PGRDG+PG GE G G Sbjct: 1764 GPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPS 1823 Query: 2201 GRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAP 2260 G G PG G G PG G GE G G G G G G G +G GP+G GA G Sbjct: 1824 GPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGIL 1883 Query: 2261 GERGRTGPLGRKGEPGE--PGPKGGIGNRGPRGETGDDGRDGVGSE-------------- 2304 G +G G G G PG+ PG GG G +G RGETG G G+ E Sbjct: 1884 GPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVD 1943 Query: 2305 -----------------------------------GRRGKKGERGFPGYPGPKGNPGEPG 2329 G +G GE+G PG GP G PGE G Sbjct: 1944 RLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERG 2003 Query: 2330 LNGTTGPKGIR-------GRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373 L G G G + G RG GP G+ G+ G PG PG G G G++ Sbjct: 2004 LKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEA 2054 Score = 236 bits (602), Expect = 3e-61 Identities = 148/338 (43%), Positives = 167/338 (49%), Gaps = 47/338 (13%) Query: 2051 PKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPG---EKGEVG 2107 PKG GE G G G G PG+ G PG G G QG PG KG RGFPG G G Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPG 1311 Query: 2108 EIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQER 2167 G G G G KG PG G +G+PG RG +GP+GE G G V PG PG+ + Sbjct: 1312 RAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKG-DP 1370 Query: 2168 GPKGETGDLGPMGVPGRDGVPGGPGET--GKNGGFGRRGPPGAKGNKGGPGQPGFEGEQG 2225 GP G G GP+G PG G PG PG G G G RGPPG PG+PG G Sbjct: 1371 GPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPG--- 1427 Query: 2226 TRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIG 2285 G+ GP GP GPPG GE+G S GA G PG+ G G G +G PG GPKG G Sbjct: 1428 LPGSPGPQGPVGPPGKKGEKGDS----EDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRG 1483 Query: 2286 NRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGN 2345 GP GE G+ KGERG PG G +G PG G G GP+G Sbjct: 1484 FPGPLGEAGE--------------KGERGPPGPAGSRGLPGVAGRPGAKGPEG------- 1522 Query: 2346 SGPPGIV---GQKGDPGYPGP--------AGPKGNRGD 2372 PPG G+KG+PG PG AGPKG +GD Sbjct: 1523 --PPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGD 1558 Score = 234 bits (598), Expect = 8e-61 Identities = 144/367 (39%), Positives = 174/367 (47%), Gaps = 66/367 (17%) Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPG--------ERGPPG 2077 E+ G P G+ G GP+G GP G G G G GD+G PG ERG PG Sbjct: 2423 ERGLAGPP----GREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPG 2478 Query: 2078 VNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDK----GLPGSSGEKGNP 2133 + G G G G RG+ G G GE+GE G++G GL G+ GD G PG G KG+ Sbjct: 2479 IRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDM 2538 Query: 2134 GRRG------DKGPRGEKGERGD------------------------------VGIRGDP 2157 G RG DKGPRG+ G+ GD GI GDP Sbjct: 2539 GERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDP 2598 Query: 2158 GNPGQDSQE--RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKG---NK 2212 G+PG+D RG KG+ G +GP G+ G GV G G G+ G G GPPG G +K Sbjct: 2599 GSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHK 2658 Query: 2213 GGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRK 2272 G G+PG G+ G G +G GP G G G+ G G +G G G PG G GP G Sbjct: 2659 GEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGND 2718 Query: 2273 GEPGEPGPKGGIGNRGPRGETGDDGRDGVGSE---------GRRGKKGERGFPGYPGPKG 2323 G G PGP G +G RGP G G G G E G G++GE+G PG GP+G Sbjct: 2719 GSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRG 2778 Query: 2324 NPGEPGL 2330 GE L Sbjct: 2779 EKGEAAL 2785 Score = 207 bits (526), Expect = 2e-52 Identities = 137/319 (42%), Positives = 162/319 (50%), Gaps = 39/319 (12%) Query: 2038 GQRGDRGPIGSIGPKGIPGED----GYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGV 2093 G+RG++G +GS G KG G+ G G G +G GERGP G++G +G +G G G Sbjct: 2502 GERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGD 2561 Query: 2094 KGSRGFPGEKGEVGEIGLDGLDGEDGDKGL------PGSSGEKGNPGRRGDKG------P 2141 KGS+G PG+KG G GL GL G G G PGS G+ G PG RG+KG P Sbjct: 2562 KGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGP 2621 Query: 2142 RGEKGERGDVGIRGDPGNPGQDSQERGPKGETG------DLGPMGVPGRDGVPGGPGETG 2195 RG KGERG G G G G D E GP G G ++G GVPG+ G PG G G Sbjct: 2622 RGLKGERGVKGACGLDGEKG-DKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIG 2680 Query: 2196 KNG--GF-GRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRG 2252 G GF G+ GP G +G KG G PG G G G G AGP GPPG +G +G G +G Sbjct: 2681 PKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQG 2740 Query: 2253 SGGAAGAPGER-----GRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSE--- 2304 G G PGER G G G +GE G PGP G G +G T DD R V E Sbjct: 2741 QKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIRGFVRQEMSQ 2800 Query: 2305 -----GRRGKKGERGFPGY 2318 G+ G R P Y Sbjct: 2801 HCACQGQFIASGSRPLPSY 2819 Score = 180 bits (457), Expect = 2e-44 Identities = 110/250 (44%), Positives = 130/250 (52%), Gaps = 33/250 (13%) Query: 2141 PRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGF 2200 P+G+KGE G++G+RG G PG G+PGR G PG G G Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDP----------------GLPGRTGAPGPQGPPGSATAK 1295 Query: 2201 GRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAP 2260 G RG PGA G PG PG G GT GA G G G PG G+ G GPRG G GAP Sbjct: 1296 GERGFPGADGR---PGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAP 1352 Query: 2261 GER-GRTGP--LGRKGEPGE---PGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERG 2314 G+ G GP GRKG+PG PGP+G +G+ GPRG G G G +G RG++G G Sbjct: 1353 GQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPG 1412 Query: 2315 ------FPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNS--GPPGIVGQKGDPGYPGPAGP 2366 PG PG G PG PG G GP G +G +G+S G PG+ GQ G PG GP GP Sbjct: 1413 PGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGP 1472 Query: 2367 KGNRGDSIDQ 2376 G G D+ Sbjct: 1473 PGAIGPKGDR 1482 Score = 109 bits (273), Expect = 4e-23 Identities = 94/331 (28%), Positives = 153/331 (46%), Gaps = 23/331 (6%) Query: 9 LVAVFCL-FLSGFPTTHAQ-QQQADVKNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVV 66 LVA C L+ P AQ +++ AADI+FL+D S +IG +F+ VR FL +V Sbjct: 6 LVAALCAGILAEAPRVRAQHRERVTCTRLYAADIVFLLDGSSSIGRSNFREVRSFLEGLV 65 Query: 67 K--SLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEY 124 S A FA VQ++ +P TEF L+ + +V+ I +SY GG +TG + + Sbjct: 66 LPFSGAASAQGVRFATVQYSDDPRTEFGLDALGSGGDVIRAIRELSYKGGNTRTGAAILH 125 Query: 125 IMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDADEGA 184 + A GVP+V +++TDG S+D + + LK V +FA+G+++AD Sbjct: 126 VADHVFLPQL---ARPGVPKVCILITDGKSQDLVDTAAQRLKGQGVKLFAVGIKNADPEE 182 Query: 185 LKEIASEPLNMHMFNLENFT---SLHDIVGNLVSCVHSSVSPERAGD--TETLKDITAQD 239 LK +AS+P + F + +F+ +L +V V V R D T +D+ + Sbjct: 183 LKRVASQPTSDFFFFVNDFSILRTLLPLVSRRVCTTAGGVPVTRPPDDSTSAPRDLVLSE 242 Query: 240 SADIIFLIDGSNNTGSV-NFAVILDFLVNLLEKLPIGTQQIRV----------GVVQFSD 288 + + + +G V + V L L + LP Q++ V G+ ++ Sbjct: 243 PSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLRGLRPLTE 302 Query: 289 EPRTMFSLDTYSTKAQVLGAVKALGFAGGEL 319 T+ +L S V G + G EL Sbjct: 303 YQVTVIALYANSIGEAVSGTARTTALEGPEL 333 Score = 99.4 bits (246), Expect = 5e-20 Identities = 66/198 (33%), Positives = 107/198 (54%), Gaps = 12/198 (6%) Query: 639 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD--IGNDNIRVGLVQFSDTPVTEFSLNTY 696 DI+FLLDGS+++G++NF VR F+ LV +R VQ+SD P TEF L+ Sbjct: 38 DIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDAL 97 Query: 697 QTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSE 756 + D++ +R+L +GG+ TG+A+ +V + F R VP++ +L+T G+S+ Sbjct: 98 GSGGDVIRAIRELSYKGGN-TRTGAAILHVADHVFLP---QLARPGVPKVCILITDGKSQ 153 Query: 757 DSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPS--LVYLMDDFSSLPALPQQLIQ 814 D AA L G+ F VG A+ EL+++A P+ + ++DFS L L + + Sbjct: 154 DLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLPLVSR 213 Query: 815 PLTTYVSGGVEEVPLAQP 832 + T G VP+ +P Sbjct: 214 RVCTTAGG----VPVTRP 227 Score = 95.1 bits (235), Expect = 1e-18 Identities = 78/222 (35%), Positives = 113/222 (50%), Gaps = 16/222 (7%) Query: 1233 DVVFLIDGSQSAG-PEFQYVRTLIERLVDYLD--VGFDTTRVAVIQFSDDPKVEFLLNAH 1289 D+VFL+DGS S G F+ VR+ +E LV R A +Q+SDDP+ EF L+A Sbjct: 38 DIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDAL 97 Query: 1290 SSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSD 1349 S +V A++ L KGG G A+ +V+ ++F L GVP+ +LI+ GKS Sbjct: 98 GSGGDVIRAIRELSYKGG-NTRTGAAILHVADHVF---LPQLARPGVPKVCILITDGKSQ 153 Query: 1350 DEVDDPAVELKQFGVAPFTIA-RNADQEELVKISLSP--EYVFSVSTFRELPSLEQKLLT 1406 D VD A LK GV F + +NAD EEL +++ P ++ F V+ F L +L + Sbjct: 154 DLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLPLVSR 213 Query: 1407 PITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVR 1448 + T + TR PP S D+V SS+ +R Sbjct: 214 RVCTTAGG-----VPVTR-PPDDSTSAPRDLVLSEPSSQSLR 249 Score = 92.8 bits (229), Expect = 5e-18 Identities = 59/164 (35%), Positives = 91/164 (55%), Gaps = 10/164 (6%) Query: 1638 ADIVFLLDGSINFRRDSFQEVLRFVSEIV--DTVYEDGDSIQVGLVQYNSDPTDEFFLKD 1695 ADIVFLLDGS + R +F+EV F+ +V + ++ VQY+ DP EF L Sbjct: 37 ADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDA 96 Query: 1696 FSTKRQIIDAINKVVYKGGRHANTKVG--LEHLRVNHFVPEAGSRLDQRVPQIAFVITGG 1753 + +I AI ++ YKGG NT+ G + H+ + F+P+ VP++ +IT G Sbjct: 97 LGSGGDVIRAIRELSYKGG---NTRTGAAILHVADHVFLPQLAR---PGVPKVCILITDG 150 Query: 1754 KSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAF 1797 KS + + L +GVK+FAVG++N D EE+ ++AS + F Sbjct: 151 KSQDLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDF 194 Score = 90.5 bits (223), Expect = 2e-17 Identities = 69/205 (33%), Positives = 98/205 (47%), Gaps = 13/205 (6%) Query: 1434 AADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSK--VRVGVVQFSNDVFPEFYLK 1491 AADIVFL+D S + F +R F+ +V + S VR VQ+S+D EF L Sbjct: 36 AADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLD 95 Query: 1492 TYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGK 1551 S V+ AIR L +GG+ TG A+ VA ++F+ GVP+ +L+ GK Sbjct: 96 ALGSGGDVIRAIRELSYKGGNT-RTGAAILHVADHVFLPQLA---RPGVPKVCILITDGK 151 Query: 1552 SQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPR--LVFTVREF----RELPNI 1605 SQD V AQ ++ G+ VG +N D EL+ + + P F V +F LP + Sbjct: 152 SQDLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLPLV 211 Query: 1606 EERIMNSFGPSAATPAPPGVDTPPP 1630 R+ + G T PP T P Sbjct: 212 SRRVCTTAGGVPVT-RPPDDSTSAP 235 Score = 90.5 bits (223), Expect = 2e-17 Identities = 55/154 (35%), Positives = 86/154 (55%), Gaps = 6/154 (3%) Query: 445 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDL--IQVAVAQYADTVRPEFYFNTH 502 DIVFL+DGSS++G +NF +R F+ ++ ++ A QY+D R EF + Sbjct: 38 DIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDAL 97 Query: 503 PTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSL 562 + +VI A+R++ G+ TG+A+ V +++F A G+PK+ +LIT GKS Sbjct: 98 GSGGDVIRAIRELSYKGGNTR-TGAAILHVADHVFLPQL---ARPGVPKVCILITDGKSQ 153 Query: 563 DEISQPAQELKRSSIMAFAIGNKGADQAELEEIA 596 D + AQ LK + FA+G K AD EL+ +A Sbjct: 154 DLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVA 187 Score = 88.6 bits (218), Expect = 9e-17 Identities = 73/220 (33%), Positives = 109/220 (49%), Gaps = 15/220 (6%) Query: 1029 DVVFLLDGSEGV-RSGFPLLKEFVQRVVESLD--VGQDRVRVAVVQYSDRTRPEFYLNSY 1085 D+VFLLDGS + RS F ++ F++ +V VR A VQYSD R EF L++ Sbjct: 38 DIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDAL 97 Query: 1086 MNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSG 1145 + DV+ A+R+L+ GG T TGAA+ V ++ + GVP++ I++T +S Sbjct: 98 GSGGDVIRAIRELSYKGGNT-RTGAAILHVADHVFLPQLA---RPGVPKVCILITDGKSQ 153 Query: 1146 DDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIP--DFAVAIPTFRQLGTVQQVISE 1203 D V + +K G +GI NAD E++ ++ P DF + F L T+ ++S Sbjct: 154 DLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLPLVSR 213 Query: 1204 RVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQS 1243 RV PV +P P RD+V SQS Sbjct: 214 RVCTTAGG-----VPVTRP-PDDSTSAPRDLVLSEPSSQS 247 Score = 86.3 bits (212), Expect = 4e-16 Identities = 69/223 (30%), Positives = 103/223 (46%), Gaps = 16/223 (7%) Query: 240 SADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIG----TQQIRVGVVQFSDEPRTMFS 295 +ADI+FL+DGS++ G NF + FL L+ LP Q +R VQ+SD+PRT F Sbjct: 36 AADIVFLLDGSSSIGRSNFREVRSFLEGLV--LPFSGAASAQGVRFATVQYSDDPRTEFG 93 Query: 296 LDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISA 355 LD + V+ A++ L + GG G A+ V ++ F GVP+V +LI+ Sbjct: 94 LDALGSGGDVIRAIRELSYKGGN-TRTGAAILHVADHVFLP---QLARPGVPKVCILITD 149 Query: 356 GPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATD--DNLVFTVPEFRSFGDLQE 413 G S D + LK V F +G + A EL+ +A+ + F V +F L Sbjct: 150 GKSQDLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLP 209 Query: 414 KLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSAL 456 + + A V +PP T RD+V S +L Sbjct: 210 LVSRRVCTTAGGVPVTRPPDDSTSA----PRDLVLSEPSSQSL 248 Score = 77.0 bits (188), Expect = 3e-13 Identities = 60/216 (27%), Positives = 95/216 (43%), Gaps = 15/216 (6%) Query: 837 DILFLFDGSANLV-GQFPVVRDFLYKIIDELN--VKPEGTRIAVAQYSDDVKVESRFDEH 893 DI+FL DGS+++ F VR FL ++ + +G R A QYSDD + E D Sbjct: 38 DIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDAL 97 Query: 894 QSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSS 953 S +++ ++ + K G G A+ + ++F+ GV + +L+ G+S Sbjct: 98 GSGGDVIRAIRELSYKGGNT-RTGAAILHVADHVFLPQLA---RPGVPKVCILITDGKSQ 153 Query: 954 DRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPA--FILAAESLPKIGDLHPQIVN 1011 D VD A LK GV F KNADP EL+++ P F + L P + Sbjct: 154 DLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLPLVSR 213 Query: 1012 LLKSVHNGAPA------PVSGEKDVVFLLDGSEGVR 1041 + + G P S +D+V S+ +R Sbjct: 214 RVCTTAGGVPVTRPPDDSTSAPRDLVLSEPSSQSLR 249 Score = 70.1 bits (170), Expect = 3e-11 Identities = 33/86 (38%), Positives = 52/86 (60%), Gaps = 4/86 (4%) Query: 3083 PPQPARSASSSTINLMVSTEPLALTETDI-CKLPKDEGTCRDFILKWYYDP---NTKSCA 3138 PP+ + S ++ +P A ++D C LP DEG+C + L+WY+ +T++C Sbjct: 2846 PPEDDEYSEYSEYSVEEYQDPEAPWDSDDPCSLPLDEGSCTAYTLRWYHRAVTGSTEACH 2905 Query: 3139 RFWYGGCGGNENKFGSQKECEKVCAP 3164 F YGGCGGN N+FG+++ CE+ C P Sbjct: 2906 PFVYGGCGGNANRFGTREACERRCPP 2931 Score = 48.5 bits (114), Expect = 1e-04 Identities = 46/205 (22%), Positives = 88/205 (42%), Gaps = 3/205 (1%) Query: 1021 PAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLD-VGQDRVRVAVVQYSDRTRPE 1079 P G DVVFL ++ + ++R+V +L +G V+V ++ YS R P Sbjct: 1046 PVCPRGLADVVFLPHATQDNAHRAEATRRVLERLVLALGPLGPQAVQVGLLSYSHRPSPL 1105 Query: 1080 FYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVL 1139 F LN + ++ +R + + N G A+ R +L A R + VP ++++L Sbjct: 1106 FPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHRYMLAPDAPGR-RQHVPGVMVLL 1164 Query: 1140 TADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQ 1199 + D+ +P + G + +G+ AD +++ ++ D ++ Q Sbjct: 1165 VDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLAPGMDSVQTFFAVDDGPSLDQ 1224 Query: 1200 VISERVTQLTREELSRLQPVLQPLP 1224 +S T L + + QP +P P Sbjct: 1225 AVSGLATALCQASFT-TQPRPEPCP 1248 Score = 42.4 bits (98), Expect = 0.007 Identities = 43/187 (22%), Positives = 80/187 (42%), Gaps = 11/187 (5%) Query: 1428 PAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRL-----NIGPSKVRVGVVQFSN 1482 P AD+VFL +++ AH + R++ RL +GP V+VG++ +S+ Sbjct: 1046 PVCPRGLADVVFLPHATQDN-----AHRAEATRRVLERLVLALGPLGPQAVQVGLLSYSH 1100 Query: 1483 DVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQ 1542 P F L +L IR + S N G A+ R + A R VP Sbjct: 1101 RPSPLFPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHRYMLAPDAPGR-RQHVPG 1159 Query: 1543 HLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFREL 1602 +VL++ + D+ + ++SG+ + +G D +L+ + V T + Sbjct: 1160 VMVLLVDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLAPGMDSVQTFFAVDDG 1219 Query: 1603 PNIEERI 1609 P++++ + Sbjct: 1220 PSLDQAV 1226 Score = 40.0 bits (92), Expect = 0.037 Identities = 58/229 (25%), Positives = 94/229 (41%), Gaps = 26/229 (11%) Query: 1202 SERVTQLTR--EELSRLQPVLQPLPSPGVG---------GKRDVVFLIDGSQSAGPEFQY 1250 S+RVT L + L PVL + P G DVVFL +Q + Sbjct: 1012 SQRVTGLEPGVSYIFSLTPVLDGVRGPEASVTQTPVCPRGLADVVFLPHATQDNAHRAEA 1071 Query: 1251 VRTLIERLVDYL-DVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLR------ 1303 R ++ERLV L +G +V ++ +S P F LN ++ +QR+R Sbjct: 1072 TRRVLERLVLALGPLGPQAVQVGLLSYSHRPSPLFPLN---GSHDLGIILQRIRDMPYMD 1128 Query: 1304 PKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFG 1363 P G N+G A+ R + R + VP +VL+ ++ P E + G Sbjct: 1129 PSGN---NLGTAVVTAHRYMLAPDAPGR-RQHVPGVMVLLVDEPLRGDIFSPIREAQASG 1184 Query: 1364 VAPFTIA-RNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTL 1411 + + AD E+L +++ + V + + PSL+Q + T L Sbjct: 1185 LNVVMLGMAGADPEQLRRLAPGMDSVQTFFAVDDGPSLDQAVSGLATAL 1233 Score = 39.3 bits (90), Expect = 0.063 Identities = 47/198 (23%), Positives = 83/198 (41%), Gaps = 21/198 (10%) Query: 2603 RPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFA 2662 R R+R D+ F+LD + + F E++ ++ LV + AS Sbjct: 22 RAQHRERVTCTRLYAADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGA----ASAQGV 77 Query: 2663 RVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYT 2722 R A VQ++ + EF L GS ++ + R ++ G G+AI + Sbjct: 78 RFATVQYSDDP----------RTEFGLDALGSGGDVIRAI-RELSYKGGNTRTGAAILHV 126 Query: 2723 IENVF-ESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIK 2781 ++VF P K+ +L+ G+ + AQR+ K +G +GI + + + Sbjct: 127 ADHVFLPQLARPGVPKVCILITDGKSQDLVDTAAQRL----KGQGVKLFAVGI-KNADPE 181 Query: 2782 EVYTFASEPNDVFFKLVD 2799 E+ AS+P FF V+ Sbjct: 182 ELKRVASQPTSDFFFFVN 199 Score = 37.4 bits (85), Expect = 0.24 Identities = 59/292 (20%), Positives = 114/292 (39%), Gaps = 29/292 (9%) Query: 121 GLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDA 180 GLE Q + + AG+G + T+ +PS EL+ D ++ ++ + Sbjct: 923 GLEPATQYRVRLSVLGPAGEGPSAEVTARTESPR-----VPSIELRVVDTSIDSVTLAWT 977 Query: 181 D--------------EGALKEIASEPLNMH-MFNLENFTSLHDIVGNLVSC--VHSSVSP 223 G +E+ P + + + + T L V + S V V Sbjct: 978 PVSRASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPVLDGVRG 1037 Query: 224 ERAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAV--ILDFLVNLLEKLPIGTQQIRV 281 A T+T + + AD++FL + + A +L+ LV L P+G Q ++V Sbjct: 1038 PEASVTQT--PVCPRGLADVVFLPHATQDNAHRAEATRRVLERLVLALG--PLGPQAVQV 1093 Query: 282 GVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSR 341 G++ +S P +F L+ +L ++ + + N+G A+ + Sbjct: 1094 GLLSYSHRPSPLFPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAV-VTAHRYMLAPDAPG 1152 Query: 342 VEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIA 393 + VP V+VL+ P +I + + + + LG A +L+ +A Sbjct: 1153 RRQHVPGVMVLLVDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLA 1204 Score = 33.5 bits (75), Expect = 3.4 Identities = 36/164 (21%), Positives = 64/164 (39%), Gaps = 3/164 (1%) Query: 824 VEEVPLAQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELN-VKPEGTRIAVAQYSD 882 V + P+ P D++FL + + + R L +++ L + P+ ++ + YS Sbjct: 1042 VTQTPVC-PRGLADVVFLPHATQDNAHRAEATRRVLERLVLALGPLGPQAVQVGLLSYSH 1100 Query: 883 DVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQ 942 + IL ++ M NLG A+ A RY+ A R V Sbjct: 1101 RPSPLFPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHRYMLAPDAPGR-RQHVPG 1159 Query: 943 FLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQI 986 +VLLV + P + SG+ + ADP +L ++ Sbjct: 1160 VMVLLVDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRL 1203 >gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] Length = 1604 Score = 274 bits (701), Expect = 9e-73 Identities = 159/361 (44%), Positives = 187/361 (51%), Gaps = 31/361 (8%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPG------ERGPPGVNGTQGFQGCPGQR 2091 GQRG+ GP G G G PG G G+PG G PG ERG G+ G +G G PGQ Sbjct: 1030 GQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQP 1089 Query: 2092 GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGR---RGDKGPRGEKGER 2148 G G+ G PG G GE G G GE G+ G PGS G G PG RG++GP+G GE+ Sbjct: 1090 GYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEK 1149 Query: 2149 GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208 GD G +G PG PG GP G G +G G PG G G G +G G GPPG Sbjct: 1150 GDQGFQGQPGFPGPP----GPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGP 1205 Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2268 G +G G G +G+ G G +G GPAGPPGL+G G G G G G G+ G+ GP Sbjct: 1206 PGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGP 1265 Query: 2269 LGRKGEPG------------EPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGF- 2315 G G PG PGP G +G GP G+ G G VG +G RG GERG Sbjct: 1266 PGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLA 1325 Query: 2316 --PGYPGPKGN---PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNR 2370 PG PGP G+ PGEPG +G G +G G++G GPPG G G G G AG KG Sbjct: 1326 GLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRA 1385 Query: 2371 G 2371 G Sbjct: 1386 G 1386 Score = 257 bits (656), Expect = 1e-67 Identities = 152/359 (42%), Positives = 175/359 (48%), Gaps = 26/359 (7%) Query: 2037 SGQRGDRGPIG------SIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQ 2090 +G +G+ GP G + GP G+PG G RGY G G GE GPPG G G G G Sbjct: 1077 TGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGP 1136 Query: 2091 RGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD 2150 RG +G +G GEKG+ G G G G G G PG G G PG + +KG G +G G Sbjct: 1137 RGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGL 1196 Query: 2151 VGIRGDPGNPG------------QDSQE--RGPKGETGDLGPMGVPGRDGVPGGPGETGK 2196 G G PG PG +D + RG G G G MG PG G G PG G Sbjct: 1197 PGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGP 1256 Query: 2197 NGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGIS-----GPR 2251 G G+ GPPG+ G G G+PG G QG G G GP GPPG G GIS G R Sbjct: 1257 KGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDR 1316 Query: 2252 GSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKK 2310 G+ G G G G+ GP G G PGEPG G G GP G+ G G G G G G+K Sbjct: 1317 GATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQK 1376 Query: 2311 GERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGN 2369 G+ G G G G PG+ G G GP G G RG+ G PG G G PG PG G N Sbjct: 1377 GQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVN 1435 Score = 255 bits (651), Expect = 6e-67 Identities = 158/352 (44%), Positives = 182/352 (51%), Gaps = 46/352 (13%) Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEG--GP-GERGPPGVNGT---QGFQGCPGQR 2091 G +G+RG GS G KG PG G G PG G GP GERGP G +G QGFQG PG Sbjct: 1102 GIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFP 1161 Query: 2092 GVKGSRGFPGEKGEVGEIGLD---GLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER 2148 G G GFPG+ G G G G +G G GLPGS G G PG +G G G G+ Sbjct: 1162 GPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKD 1221 Query: 2149 GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208 G G+RGDP GP G G +GP G G+ G PG P G G G+ GPPG+ Sbjct: 1222 GKPGLRGDP----------GPAGPPGLMGPPGFKGKTGHPGLP---GPKGDCGKPGPPGS 1268 Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2268 G G G+PG G QG G G GP GPPG G GIS A G G+RG TG Sbjct: 1269 TGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGIS-------AVGLKGDRGATGE 1321 Query: 2269 LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEP 2328 G G PG+PGP G+ GP GE G D G+ G+ G G++GF G PGPKG+PG Sbjct: 1322 RGLAGLPGQPGPP---GHPGPPGEPGTD-----GAAGKEGPPGKQGFYGPPGPKGDPGAA 1373 Query: 2329 GLNGTTGPKGIRGRRGNS---------GPPGIVGQKGDPGYPGPAGPKGNRG 2371 G G G KG G G GPPG G++G PG PGP+G G G Sbjct: 1374 GQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPG 1425 Score = 250 bits (638), Expect = 2e-65 Identities = 156/364 (42%), Positives = 181/364 (49%), Gaps = 37/364 (10%) Query: 2041 GDRGPIGSIG---PKGIPGEDGYRGYPGDEGGPGERGP---PGVNGTQGFQGCPGQRGVK 2094 GD G +GS G P G+PG+ G G PG G PG GP PG G G G PG +G + Sbjct: 1012 GDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGER 1071 Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154 G G G+KGE G G G G G GLPG GE+G G G+KG E G G G+ Sbjct: 1072 GLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKG---EPGPPGSEGLP 1128 Query: 2155 GDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGG 2214 G PG P ERGP+G +G+ G G G+ G PG PG G G G GPPG + KG Sbjct: 1129 GPPG-PAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGS 1187 Query: 2215 PGQPGFEGEQGTRGAQGPAG---PAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGR 2271 G G G G+ G GP G PAG GL G+ G G RG G AG PG G G G+ Sbjct: 1188 EGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGK 1247 Query: 2272 KGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNP----- 2325 G PG PGPKG G GP G TG G +G G+ G +G+ G G G PGP G P Sbjct: 1248 TGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGI 1307 Query: 2326 ------------GE---PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDP---GYPGPAGPK 2367 GE GL G GP G G G G G G++G P G+ GP GPK Sbjct: 1308 SAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPK 1367 Query: 2368 GNRG 2371 G+ G Sbjct: 1368 GDPG 1371 Score = 243 bits (620), Expect = 2e-63 Identities = 163/409 (39%), Positives = 192/409 (46%), Gaps = 74/409 (18%) Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIGPK--GIPGEDGYRGYPGDEGGPGERGPPGVNGTQG 2083 EK G P G +G GP+G G G PG DG +G G G PGE+GP G G G Sbjct: 819 EKGAQGSP----GVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPG 874 Query: 2084 -----------FQGCPG----------QRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKG 2122 F G PG Q G +G G PG G G GL G+ G +G G Sbjct: 875 ECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPG 934 Query: 2123 LPGSSGEKGN----------------PGRRGDKGPRGEKGERGDVGIRGDPGNPGQDS-- 2164 PG + E G+ G+R G EKGE+GD GI PG PG D+ Sbjct: 935 QPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGI---PGVPGLDNCA 991 Query: 2165 ------------QERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRG-------- 2204 + RG E GD G +G PG G PG PG+ G+ G G RG Sbjct: 992 QCFLSLERPRAEEARGDNSE-GDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPI 1050 Query: 2205 -PPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGER 2263 PPG G G PG PG +GE+G G G G GPPG G G +GP G G GER Sbjct: 1051 GPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGP---PGLPGIKGER 1107 Query: 2264 GRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPK 2322 G TG G KGEPG PG +G G GP G G+ G G G +G +G +G+ GFPG PGP Sbjct: 1108 GYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPP 1167 Query: 2323 GNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 G PG+ G G GP+ +G G GP G+ G G PG PG GP G G Sbjct: 1168 GFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDG 1216 Score = 243 bits (620), Expect = 2e-63 Identities = 163/441 (36%), Positives = 196/441 (44%), Gaps = 107/441 (24%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPG------ERGPPGVNGTQGFQGCPGQ 2090 +G RG+RGP G+ G KG G G G+PG G PG GPPG +G +G G Sbjct: 1134 AGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGP 1193 Query: 2091 RGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD 2150 G+ GS G PG G G GLDGLDG+DG GL G G G PG G G +G+ G G Sbjct: 1194 SGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGL 1253 Query: 2151 VGIRGDPGNPGQDSQ--ERGPKGETGDLGPMG---VPGRDGVPGGPGE------------ 2193 G +GD G PG G +GE G +GP G PG G PG PG+ Sbjct: 1254 PGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLK 1313 Query: 2194 -----TGKNGGFGRRGPPGAKGNKGGPGQPGF------EGEQGTRGAQGPAGPAGPPGLI 2242 TG+ G G G PG G+ G PG+PG EG G +G GP GP G PG Sbjct: 1314 GDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAA 1373 Query: 2243 GEQGISGPRGSGGAAGAPGERGRTGPLG------RKGEPGEPGPKG-----GI------- 2284 G++G +G +G G G PG+ G GP+G +G PG PGP G G+ Sbjct: 1374 GQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDM 1433 Query: 2285 ---------------------------------------GNRGPRGETGDDGRDG----- 2300 G GP G+ G GR G Sbjct: 1434 VNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSP 1493 Query: 2301 -----VGSEGRRGKKGERGFPGYPGPKGN-----PGEPGLNGTTGPKGIRGRRGNSGPPG 2350 +G EGR+G G RG PG G KG+ GE GL G GP+G G G G G Sbjct: 1494 GLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGY-GKMGATG 1552 Query: 2351 IVGQKGDPGYPGPAGPKGNRG 2371 +GQ+G PG PGP GP G G Sbjct: 1553 PMGQQGIPGIPGPPGPMGQPG 1573 Score = 243 bits (619), Expect = 3e-63 Identities = 165/419 (39%), Positives = 189/419 (45%), Gaps = 85/419 (20%) Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGT--------------- 2081 S Q G +GP G GP G PG G +G PG+ G PG+ G G+ Sbjct: 900 SWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDC 959 Query: 2082 -QGFQGCPG---QRGVKGSRGFPGEKG-----------------------EVGEIGLDGL 2114 QG + PG ++G KG +G PG G G+ G G Sbjct: 960 VQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGS 1019 Query: 2115 DGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETG 2174 G G GLPG GE+G PG RG GP G G G G G PG PG ERG G TG Sbjct: 1020 PGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQG-ERGLTGLTG 1078 Query: 2175 DLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAG 2234 D G G PG+ G PG G G G G RG G+ G KG PG PG EG G G GP G Sbjct: 1079 DKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRG 1138 Query: 2235 PAGPPGLIGEQGISGPRGSGGAAGAPG------------------ERGRTGPLGRKGEPG 2276 GP G GE+G G +G G G PG E+G G G G PG Sbjct: 1139 ERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPG 1198 Query: 2277 EPGPKGGIGNRGPRGETGDDGRDGV-------------GSEGRRGKKGERGFPGYPGPKG 2323 PGP G G +GP G G DG+DG G G G KG+ G PG PGPKG Sbjct: 1199 SPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKG 1258 Query: 2324 NPGEPGLNGTTGPKGIRGR------RGNSGPPGIVGQKGDPGYPGPA-----GPKGNRG 2371 + G+PG G+TG G G +G GPPG VG G PG PGPA G KG+RG Sbjct: 1259 DCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRG 1317 Score = 239 bits (609), Expect = 4e-62 Identities = 154/387 (39%), Positives = 172/387 (44%), Gaps = 55/387 (14%) Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRG 2092 P G G GP G G +G G G +G G +G PG GPPG G G G PG G Sbjct: 1121 PPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPG 1180 Query: 2093 ---VKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERG 2149 KGS G G G G G G G G GL G G+ G PG RGD GP G G G Sbjct: 1181 PQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMG 1240 Query: 2150 DVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAK 2209 G +G G+PG GPKG+ G GP PG G PG GE G G GR GPPG Sbjct: 1241 PPGFKGKTGHPGLP----GPKGDCGKPGP---PGSTGRPGAEGEPGAMGPQGRPGPPGHV 1293 Query: 2210 GNKGGPGQP-----------GFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAG 2258 G G PGQP G G G RG G G GPPG G G G G+ G G Sbjct: 1294 GPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEG 1353 Query: 2259 APGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPG 2317 PG++G GP G KG+PG G KG G +G G G G+ G +G G G GERG PG Sbjct: 1354 PPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPG 1413 Query: 2318 YPGPKGNPGEPGLNGTTG---------------------------------PKGIRGRRG 2344 PGP G+PG PG+ G+ G P + G Sbjct: 1414 APGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPG 1473 Query: 2345 NSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 GPPG G G PG PG G G G Sbjct: 1474 RPGPPGKDGAPGRPGAPGSPGLPGQIG 1500 Score = 236 bits (602), Expect = 3e-61 Identities = 162/407 (39%), Positives = 180/407 (44%), Gaps = 75/407 (18%) Query: 2025 AEKACCGV--PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQ 2082 AEK G+ P G G GP G GP G+ G DG G PG G PG GPPG+ G Sbjct: 1183 AEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPP 1242 Query: 2083 GFQGC---PGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDK 2139 GF+G PG G KG G PG G G G +G G G +G PG G G PG G Sbjct: 1243 GFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQP 1302 Query: 2140 GPRGE-----KGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGET 2194 GP G KG+RG G RG G PGQ G G GP G PG DG G G Sbjct: 1303 GPAGISAVGLKGDRGATGERGLAGLPGQP-------GPPGHPGPPGEPGTDGAAGKEGPP 1355 Query: 2195 GKNGGFGRRGP---PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQG---IS 2248 GK G +G GP PGA G KG G+ G G G G G GP GPPG GE+G Sbjct: 1356 GKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAP 1415 Query: 2249 GPRGSGGAAGAPGERG------------------------------------------RT 2266 GP GS G G PG G R Sbjct: 1416 GPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRP 1475 Query: 2267 GPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKG--------ERGFPG 2317 GP G+ G PG PG G G G G G G GV G G +G+KG E G PG Sbjct: 1476 GPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPG 1535 Query: 2318 YPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPA 2364 PGP+G PG G G TGP G +G G GPPG +GQ G G+ P+ Sbjct: 1536 PPGPQGPPGY-GKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPS 1581 Score = 233 bits (594), Expect = 2e-60 Identities = 164/455 (36%), Positives = 192/455 (42%), Gaps = 110/455 (24%) Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGI--PGEDGYRGYPGDEGGPG------ERGPPGVNGTQ 2082 G +G+ G GP G GP+G+ PG+ G G PG +G PG E GPPG G Q Sbjct: 732 GTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPG-RGVQ 790 Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGL--------------PGSSG 2128 G QG PG G+ G +G PG +G G G G G G KG PG G Sbjct: 791 GPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDG 850 Query: 2129 EKGNPGRRG---DKGPRGEKGE--------RGDVGIRGDPGNPGQ---DSQERGPKGETG 2174 ++G G RG +KGPRGEKGE +GD+ G PG PG S + GP+G G Sbjct: 851 QQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPG 910 Query: 2175 DLGP---------MGVPGRDGVPGGP---------------------------------- 2191 GP GVPG +G+PG P Sbjct: 911 IPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYL 970 Query: 2192 ---GETGKNG--------------------------GFGRRGPPGAKGNKGGPGQPGFEG 2222 GE G G G G PG G+ G PG PG G Sbjct: 971 VEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPG 1030 Query: 2223 EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKG 2282 ++G G G G GPPG IG G G GS G G GERG TG G KGEPG PG G Sbjct: 1031 QRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPG 1090 Query: 2283 GIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRG 2341 G GP G G G G GS G +G+ G G G PGP G G G G G G +G Sbjct: 1091 YPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKG 1150 Query: 2342 RRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQ 2376 +G G PG G G PG+PG G G G ++ Sbjct: 1151 DQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEK 1185 Score = 233 bits (593), Expect = 3e-60 Identities = 156/391 (39%), Positives = 193/391 (49%), Gaps = 60/391 (15%) Query: 2033 PCKCS-GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQR 2091 P +C+ G +G++G G++GP G+PG G +G G++G G +G PG G G PG+ Sbjct: 369 PLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGR---PGEI 425 Query: 2092 GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKG-PRGEKGERGD 2150 V G +G +KG+ G +G +GL GE G GLPG G G PG GD G P G KG++G Sbjct: 426 CVIGPKG---QKGDPGFVGPEGLAGEPGPPGLPGPPGI-GLPGTPGDPGGPPGPKGDKGS 481 Query: 2151 VGIRGDPGNPGQDSQERGPKGETGD------LGPMGVPGRDGVPGGPGETGKNGG-FGRR 2203 GI G G PG + G KGE GD P G G+PG PG G+ G R Sbjct: 482 SGIPGKEG-PGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPAR 540 Query: 2204 GPPGAKGNKGGPGQP-----------------GFEGEQGTRG--AQGPAGPAGPPGLIGE 2244 G PG +G KG G+P G G+ G+ G G G AG PGL GE Sbjct: 541 GDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGE 600 Query: 2245 QGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGG---------IGNRGPRGETGD 2295 +G G G G+ G PG G G G KGEP EP P + GP GE G+ Sbjct: 601 KGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGE 660 Query: 2296 DGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355 G G G G++GK GERG G G GNPG+PG GTTG G+ G G GP G G+K Sbjct: 661 PGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEK 720 Query: 2356 GD---------------PGYPGPAGPKGNRG 2371 GD G PG GPKG +G Sbjct: 721 GDGCTACPSLQGTVTDMAGRPGQPGPKGEQG 751 Score = 224 bits (571), Expect = 1e-57 Identities = 154/391 (39%), Positives = 181/391 (46%), Gaps = 62/391 (15%) Query: 2031 GVPC-KCSGQRGDRGPIGSIGPKGIPGEDGYR--GYPGDEGGPGERGPPGVNGTQGFQGC 2087 G PC CS G + + S G G G G+ G PG G PG +G G G G G Sbjct: 553 GEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGS 612 Query: 2088 PGQRGVKGSRGFPGEKGEV------------GEIGLDGLDGEDGDKGLPGSSGEKGNPGR 2135 PG G G G G KGE G++ + L G G+KG PG G G PG+ Sbjct: 613 PGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGF-GLPGK 671 Query: 2136 RGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDG--------- 2186 +G G RG KG++GD G GDPG PG + G GE G GP G G G Sbjct: 672 QGKAGERGLKGQKGDAGNPGDPGTPGTTGRP-GLSGEPGVQGPAGPKGEKGDGCTACPSL 730 Query: 2187 ---VPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIG 2243 V G G+ G G +GP G G G PGQPG G QG G +G G GPPG Sbjct: 731 QGTVTDMAGRPGQPGPKGEQGPEGV-GRPGKPGQPGLPGVQGPPGLKGVQGEPGPPG--- 786 Query: 2244 EQGISGPRGSGGA------AGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGE--TGD 2295 +G+ GP+G GA G PG RG GP G KG G PG KG G GP G +G Sbjct: 787 -RGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGP 845 Query: 2296 DGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPG-----------LNGTTGPKGI----R 2340 GRD G++G+ G RG PG GP+G GEPG +G G G+ Sbjct: 846 PGRD-----GQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSS 900 Query: 2341 GRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371 + G GPPGI G G PG PG G GN G Sbjct: 901 WQPGPQGPPGIPGPPGPPGVPGLQGVPGNNG 931 Score = 221 bits (564), Expect = 7e-57 Identities = 159/410 (38%), Positives = 186/410 (45%), Gaps = 69/410 (16%) Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGV------NGTQGF 2084 G+P G GP G G GIPG++G G PG G GE+G P G Q F Sbjct: 461 GLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNF 520 Query: 2085 QGCPGQRGVKGSRGFP-------------GEKGE--------VGEIGLDGLDGEDGDKGL 2123 G PG+ G KG G P GEKGE VG L G GD G Sbjct: 521 VGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGS 580 Query: 2124 PGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE--RGPKGET-------- 2173 PG G G PGR G G +GEKG G+ G G PG PG +G KGE Sbjct: 581 PGF-GLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALS 639 Query: 2174 ----GDL------GPMGVPGRDGVPGG--PGETGKNGGFGRRGPPGAKGNKGGPGQPGFE 2221 GD+ GP G G G PG PG+ GK G G +G G GN G PG PG Sbjct: 640 NLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTT 699 Query: 2222 GEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSG------GAAGAPGERGRTGP--LGRKG 2273 G G G G GPAGP G G+ + P G G G PG +G GP +GR G Sbjct: 700 GRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPG 759 Query: 2274 EPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGY---PGPKGNPGEPGL 2330 +PG+PG G G G +G G+ G G G +G +G+ G G PG PGP+G PG G Sbjct: 760 KPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGE 819 Query: 2331 NGTTGPKGIRGRRGN--------SGPPGIVGQKGDPGYPGPAGPKGNRGD 2372 G G G++G G SGPPG GQ+G G G G KG RG+ Sbjct: 820 KGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGE 869 Score = 220 bits (561), Expect = 2e-56 Identities = 164/437 (37%), Positives = 197/437 (45%), Gaps = 98/437 (22%) Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGY---RGYPGDEGGPGERGPPGVN--GTQGFQ 2085 GVP K G+ G G I IGPKG G+ G+ G G+ G PG GPPG+ GT G Sbjct: 411 GVPGK-PGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDP 469 Query: 2086 GCP-GQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDK---------------GLPGSSGE 2129 G P G +G KGS G PG++G G+ G G+ GE GD GLPG G Sbjct: 470 GGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGP 529 Query: 2130 KGNPG----RRGDKGPRGEKGERGD-----------------VGIRGDPGNPGQDSQ--- 2165 KG PG RGD G +G KGE+G+ G GD G+PG Sbjct: 530 KGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLP 589 Query: 2166 -ERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPP------------------ 2206 G G G+ G G G G PG PG G G G +G P Sbjct: 590 GRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVV 649 Query: 2207 ---GAKGNKGGPGQPGF-----EGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAG 2258 G G KG PG PGF +G+ G RG +G G AG PG + G G G G +G Sbjct: 650 ALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPG---DPGTPGTTGRPGLSG 706 Query: 2259 APGERGRTGPLGRKGE------------------PGEPGPKGGIGNRGPRGETGDDGRDG 2300 PG +G GP G KG+ PG+PGPKG G G G G G+ G Sbjct: 707 EPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGV-GRPGKPGQPG 765 Query: 2301 V-GSEGRRGKKGERGFPGYPGP--KGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGD 2357 + G +G G KG +G PG PG +G GEPG G G +G+ G RG GP G G +G Sbjct: 766 LPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGS 825 Query: 2358 PGYPGPAGPKGNRGDSI 2374 PG G GP G G S+ Sbjct: 826 PGVKGATGPVGPPGASV 842 Score = 142 bits (358), Expect = 5e-33 Identities = 105/306 (34%), Positives = 121/306 (39%), Gaps = 74/306 (24%) Query: 2038 GQRGDRG--PIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKG 2095 GQ G G +G G +G GE G G PG G PG GPPG GT G G G G +G Sbjct: 1300 GQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQG 1359 Query: 2096 SRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRG 2155 G PG KG+ G G G GE G G+PG G+ G+ G G GP GE+G G G G Sbjct: 1360 FYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSG 1419 Query: 2156 DPGNPG----------QDSQER----------------------------------GPKG 2171 PG PG D +R GP G Sbjct: 1420 SPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPG 1479 Query: 2172 ETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQG 2231 + G G G PG G+PG G G+ G G RG PG KG KG G G GE G G G Sbjct: 1480 KDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGI-GIAGENGLPGPPG 1538 Query: 2232 PAGPAG--------------------PPGLIGEQGISGPRGSGGAAGA-------PGERG 2264 P GP G PPG +G+ G +G GA P + Sbjct: 1539 PQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKT 1598 Query: 2265 RTGPLG 2270 GP G Sbjct: 1599 MKGPFG 1604 Score = 139 bits (351), Expect = 3e-32 Identities = 98/280 (35%), Positives = 122/280 (43%), Gaps = 55/280 (19%) Query: 2156 DPGNPGQDSQERG---PKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNK 2212 +P N D+Q G K E G + P G N GP G KG + Sbjct: 283 EPQNSEVDAQLTGRISQKAERGAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGER 342 Query: 2213 GGPGQPGFEGEQGTRG--------------AQGP---------AGPAGPPGLIGEQGISG 2249 G PG PG +GE+G RG A+GP GP+G PG GE+G G Sbjct: 343 GLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKG 402 Query: 2250 PRGSGGAAGAPGERGR---------TGPLGRKGEPGEPGPKGGIGNRGPRGETGDDG--- 2297 +G GG G PG+ GR GP G+KG+PG GP+G G GP G G G Sbjct: 403 EKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGL 462 Query: 2298 ----RDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTG---------PKGIRGRRG 2344 D G G +G KG G PG GP G PG+PG+ G G P+G + G Sbjct: 463 PGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVG 522 Query: 2345 NSGPPGIVGQKGDP----GYPGPAGPKGNRGDSIDQCALI 2380 G PG G+ GDP G PG G KG +G+ C+ + Sbjct: 523 LPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSV 562 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.136 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 128,395,349 Number of Sequences: 37866 Number of extensions: 6858436 Number of successful extensions: 144218 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 375 Number of HSP's successfully gapped in prelim test: 1016 Number of HSP's that attempted gapping in prelim test: 29393 Number of HSP's gapped (non-prelim): 16921 length of query: 3177 length of database: 18,247,518 effective HSP length: 121 effective length of query: 3056 effective length of database: 13,665,732 effective search space: 41762476992 effective search space used: 41762476992 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.