Guide to the Human Genome
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Search of human proteins with 55743098

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
sapiens]
         (3177 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s...  6284   0.0  
gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s...  5816   0.0  
gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo ...  4815   0.0  
gi|240255540 alpha 3 type VI collagen isoform 3 precursor [Homo ...  2293   0.0  
gi|240255542 alpha 3 type VI collagen isoform 2 precursor [Homo ...  1910   0.0  
gi|156616290 collagen type VI alpha 6 [Homo sapiens]                 1144   0.0  
gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]             1032   0.0  
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]               336   2e-91
gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]       335   4e-91
gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Hom...   325   4e-88
gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [H...   317   1e-85
gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Ho...   317   1e-85
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     307   9e-83
gi|154759255 collagen, type XXVIII precursor [Homo sapiens]           301   5e-81
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      298   7e-80
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]              296   2e-79
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   293   2e-78
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   293   2e-78
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   289   3e-77
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   289   3e-77
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   289   3e-77
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]      286   2e-76
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     286   2e-76
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]   285   5e-76
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...   282   4e-75
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...   282   4e-75
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...   282   4e-75
gi|48762934 alpha 2 type I collagen [Homo sapiens]                    280   2e-74
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         277   1e-73
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]       274   9e-73

>gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
            sapiens]
          Length = 3177

 Score = 6284 bits (16304), Expect = 0.0
 Identities = 3177/3177 (100%), Positives = 3177/3177 (100%)

Query: 1    MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVRE 60
            MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVRE
Sbjct: 1    MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVRE 60

Query: 61   FLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGK 120
            FLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGK
Sbjct: 61   FLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGK 120

Query: 121  GLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDA 180
            GLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDA
Sbjct: 121  GLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDA 180

Query: 181  DEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDS 240
            DEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDS
Sbjct: 181  DEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDS 240

Query: 241  ADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYS 300
            ADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYS
Sbjct: 241  ADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYS 300

Query: 301  TKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSD 360
            TKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSD
Sbjct: 301  TKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSD 360

Query: 361  EIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIV 420
            EIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIV
Sbjct: 361  EIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIV 420

Query: 421  GVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQD 480
            GVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQD
Sbjct: 421  GVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQD 480

Query: 481  LIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSS 540
            LIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSS
Sbjct: 481  LIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSS 540

Query: 541  AGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSS 600
            AGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSS
Sbjct: 541  AGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSS 600

Query: 601  LVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRD 660
            LVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRD
Sbjct: 601  LVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRD 660

Query: 661  FVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTG 720
            FVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTG
Sbjct: 661  FVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTG 720

Query: 721  SALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQ 780
            SALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQ
Sbjct: 721  SALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQ 780

Query: 781  ANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILF 840
            ANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILF
Sbjct: 781  ANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILF 840

Query: 841  LFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEIL 900
            LFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEIL
Sbjct: 841  LFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEIL 900

Query: 901  NLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPA 960
            NLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPA
Sbjct: 901  NLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPA 960

Query: 961  SNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGA 1020
            SNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGA
Sbjct: 961  SNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGA 1020

Query: 1021 PAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEF 1080
            PAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEF
Sbjct: 1021 PAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEF 1080

Query: 1081 YLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLT 1140
            YLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLT
Sbjct: 1081 YLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLT 1140

Query: 1141 ADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQV 1200
            ADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQV
Sbjct: 1141 ADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQV 1200

Query: 1201 ISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVD 1260
            ISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVD
Sbjct: 1201 ISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVD 1260

Query: 1261 YLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVS 1320
            YLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVS
Sbjct: 1261 YLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVS 1320

Query: 1321 RNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVK 1380
            RNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVK
Sbjct: 1321 RNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVK 1380

Query: 1381 ISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFL 1440
            ISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFL
Sbjct: 1381 ISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFL 1440

Query: 1441 IDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVL 1500
            IDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVL
Sbjct: 1441 IDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVL 1500

Query: 1501 DAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFA 1560
            DAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFA
Sbjct: 1501 DAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFA 1560

Query: 1561 QVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATP 1620
            QVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATP
Sbjct: 1561 QVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATP 1620

Query: 1621 APPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGL 1680
            APPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGL
Sbjct: 1621 APPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGL 1680

Query: 1681 VQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLD 1740
            VQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLD
Sbjct: 1681 VQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLD 1740

Query: 1741 QRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVG 1800
            QRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVG
Sbjct: 1741 QRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVG 1800

Query: 1801 NVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFES 1860
            NVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFES
Sbjct: 1801 NVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFES 1860

Query: 1861 KVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQ 1920
            KVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQ
Sbjct: 1861 KVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQ 1920

Query: 1921 HPYVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILV 1980
            HPYVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILV
Sbjct: 1921 HPYVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILV 1980

Query: 1981 GLERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQR 2040
            GLERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQR
Sbjct: 1981 GLERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQR 2040

Query: 2041 GDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFP 2100
            GDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFP
Sbjct: 2041 GDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFP 2100

Query: 2101 GEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNP 2160
            GEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNP
Sbjct: 2101 GEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNP 2160

Query: 2161 GQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGF 2220
            GQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGF
Sbjct: 2161 GQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGF 2220

Query: 2221 EGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGP 2280
            EGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGP
Sbjct: 2221 EGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGP 2280

Query: 2281 KGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIR 2340
            KGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIR
Sbjct: 2281 KGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIR 2340

Query: 2341 GRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCPCCYGPLECPVFP 2400
            GRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCPCCYGPLECPVFP
Sbjct: 2341 GRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCPCCYGPLECPVFP 2400

Query: 2401 TELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRF 2460
            TELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRF
Sbjct: 2401 TELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRF 2460

Query: 2461 ADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPT 2520
            ADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPT
Sbjct: 2461 ADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPT 2520

Query: 2521 RASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLEN 2580
            RASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLEN
Sbjct: 2521 RASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLEN 2580

Query: 2581 VLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKK 2640
            VLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKK
Sbjct: 2581 VLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKK 2640

Query: 2641 YIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVD 2700
            YIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVD
Sbjct: 2641 YIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVD 2700

Query: 2701 FLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVIL 2760
            FLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVIL
Sbjct: 2701 FLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVIL 2760

Query: 2761 QAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKLVDKSTELNEEPLMRFGRLLPSFV 2820
            QAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKLVDKSTELNEEPLMRFGRLLPSFV
Sbjct: 2761 QAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKLVDKSTELNEEPLMRFGRLLPSFV 2820

Query: 2821 SSENAFYLSPDIRKQCDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTSNPVTTTKPVTTT 2880
            SSENAFYLSPDIRKQCDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTSNPVTTTKPVTTT
Sbjct: 2821 SSENAFYLSPDIRKQCDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTSNPVTTTKPVTTT 2880

Query: 2881 KPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPVAAKPVATKMATVRPPVAVKPAT 2940
            KPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPVAAKPVATKMATVRPPVAVKPAT
Sbjct: 2881 KPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPVAAKPVATKMATVRPPVAVKPAT 2940

Query: 2941 AAKPVAAKPAAVRPPAAAAAKPVATKPEVPRPQAAKPAATKPATTKPMVKMSREVQVFEI 3000
            AAKPVAAKPAAVRPPAAAAAKPVATKPEVPRPQAAKPAATKPATTKPMVKMSREVQVFEI
Sbjct: 2941 AAKPVAAKPAAVRPPAAAAAKPVATKPEVPRPQAAKPAATKPATTKPMVKMSREVQVFEI 3000

Query: 3001 TENSAKLHWERAEPPGPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGLLAGQTYHVAVVC 3060
            TENSAKLHWERAEPPGPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGLLAGQTYHVAVVC
Sbjct: 3001 TENSAKLHWERAEPPGPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGLLAGQTYHVAVVC 3060

Query: 3061 YLRSQVRATYHGSFSTKKSQPPPPQPARSASSSTINLMVSTEPLALTETDICKLPKDEGT 3120
            YLRSQVRATYHGSFSTKKSQPPPPQPARSASSSTINLMVSTEPLALTETDICKLPKDEGT
Sbjct: 3061 YLRSQVRATYHGSFSTKKSQPPPPQPARSASSSTINLMVSTEPLALTETDICKLPKDEGT 3120

Query: 3121 CRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAKPGVISVMGT 3177
            CRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAKPGVISVMGT
Sbjct: 3121 CRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAKPGVISVMGT 3177


>gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo
            sapiens]
          Length = 2971

 Score = 5816 bits (15089), Expect = 0.0
 Identities = 2942/2949 (99%), Positives = 2943/2949 (99%)

Query: 229  TETLKDITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSD 288
            T   +   AQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSD
Sbjct: 23   THAQQQQAAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSD 82

Query: 289  EPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQ 348
            EPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQ
Sbjct: 83   EPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQ 142

Query: 349  VLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSF 408
            VLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSF
Sbjct: 143  VLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSF 202

Query: 409  GDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFI 468
            GDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFI
Sbjct: 203  GDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFI 262

Query: 469  AKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSA 528
            AKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSA
Sbjct: 263  AKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSA 322

Query: 529  LDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGAD 588
            LDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGAD
Sbjct: 323  LDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGAD 382

Query: 589  QAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSA 648
            QAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSA
Sbjct: 383  QAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSA 442

Query: 649  NVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQ 708
            NVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQ
Sbjct: 443  NVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQ 502

Query: 709  LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTR 768
            LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTR
Sbjct: 503  LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTR 562

Query: 769  AGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVP 828
            AGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVP
Sbjct: 563  AGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVP 622

Query: 829  LAQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVES 888
            LAQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVES
Sbjct: 623  LAQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVES 682

Query: 889  RFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLV 948
            RFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLV
Sbjct: 683  RFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLV 742

Query: 949  AGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQ 1008
            AGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQ
Sbjct: 743  AGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQ 802

Query: 1009 IVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVA 1068
            IVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVA
Sbjct: 803  IVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVA 862

Query: 1069 VVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRI 1128
            VVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRI
Sbjct: 863  VVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRI 922

Query: 1129 TEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAI 1188
            TEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAI
Sbjct: 923  TEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAI 982

Query: 1189 PTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEF 1248
            PTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEF
Sbjct: 983  PTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEF 1042

Query: 1249 QYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGR 1308
            QYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGR
Sbjct: 1043 QYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGR 1102

Query: 1309 QINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFT 1368
            QINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFT
Sbjct: 1103 QINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFT 1162

Query: 1369 IARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPP 1428
            IARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPP
Sbjct: 1163 IARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPP 1222

Query: 1429 AVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEF 1488
            AVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEF
Sbjct: 1223 AVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEF 1282

Query: 1489 YLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVL 1548
            YLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVL
Sbjct: 1283 YLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVL 1342

Query: 1549 GGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEER 1608
            GGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEER
Sbjct: 1343 GGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEER 1402

Query: 1609 IMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDT 1668
            IMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDT
Sbjct: 1403 IMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDT 1462

Query: 1669 VYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRV 1728
            VYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRV
Sbjct: 1463 VYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRV 1522

Query: 1729 NHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGK 1788
            NHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGK
Sbjct: 1523 NHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGK 1582

Query: 1789 IASNSATAFRVGNVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGSRD 1848
            IASNSATAFRVGNVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGSRD
Sbjct: 1583 IASNSATAFRVGNVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGSRD 1642

Query: 1849 QNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQP 1908
            QNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQP
Sbjct: 1643 QNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQP 1702

Query: 1909 EMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASEN 1968
            EMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASEN
Sbjct: 1703 EMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASEN 1762

Query: 1969 LRQEGVRALILVGLERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKA 2028
            LRQEGVRALILVGLERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKA
Sbjct: 1763 LRQEGVRALILVGLERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKA 1822

Query: 2029 CCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCP 2088
            CCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCP
Sbjct: 1823 CCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCP 1882

Query: 2089 GQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER 2148
            GQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER
Sbjct: 1883 GQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER 1942

Query: 2149 GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208
            GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA
Sbjct: 1943 GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2002

Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2268
            KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP
Sbjct: 2003 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2062

Query: 2269 LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEP 2328
            LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEP
Sbjct: 2063 LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEP 2122

Query: 2329 GLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCP 2388
            GLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCP
Sbjct: 2123 GLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCP 2182

Query: 2389 CCYGPLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVV 2448
            CCYGPLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVV
Sbjct: 2183 CCYGPLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVV 2242

Query: 2449 TYNNEVTTEIRFADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLM 2508
            TYNNEVTTEIRFADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLM
Sbjct: 2243 TYNNEVTTEIRFADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLM 2302

Query: 2509 RKVAVFFSNTPTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVL 2568
            RKVAVFFSNTPTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVL
Sbjct: 2303 RKVAVFFSNTPTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVL 2362

Query: 2569 PAGRDLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAE 2628
            PAGRDLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAE
Sbjct: 2363 PAGRDLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAE 2422

Query: 2629 TTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFS 2688
            TTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFS
Sbjct: 2423 TTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFS 2482

Query: 2689 LTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVP 2748
            LTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVP
Sbjct: 2483 LTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVP 2542

Query: 2749 EQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKLVDKSTELNEEP 2808
            EQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKLVDKSTELNEEP
Sbjct: 2543 EQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKLVDKSTELNEEP 2602

Query: 2809 LMRFGRLLPSFVSSENAFYLSPDIRKQCDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTS 2868
            LMRFGRLLPSFVSSENAFYLSPDIRKQCDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTS
Sbjct: 2603 LMRFGRLLPSFVSSENAFYLSPDIRKQCDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTS 2662

Query: 2869 NPVTTTKPVTTTKPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPVAAKPVATKMA 2928
            NPVTTTKPVTTTKPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPVAAKPVATKMA
Sbjct: 2663 NPVTTTKPVTTTKPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPVAAKPVATKMA 2722

Query: 2929 TVRPPVAVKPATAAKPVAAKPAAVRPPAAAAAKPVATKPEVPRPQAAKPAATKPATTKPM 2988
            TVRPPVAVKPATAAKPVAAKPAAVRPPAAAAAKPVATKPEVPRPQAAKPAATKPATTKPM
Sbjct: 2723 TVRPPVAVKPATAAKPVAAKPAAVRPPAAAAAKPVATKPEVPRPQAAKPAATKPATTKPM 2782

Query: 2989 VKMSREVQVFEITENSAKLHWERAEPPGPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGL 3048
            VKMSREVQVFEITENSAKLHWERAEPPGPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGL
Sbjct: 2783 VKMSREVQVFEITENSAKLHWERAEPPGPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGL 2842

Query: 3049 LAGQTYHVAVVCYLRSQVRATYHGSFSTKKSQPPPPQPARSASSSTINLMVSTEPLALTE 3108
            LAGQTYHVAVVCYLRSQVRATYHGSFSTKKSQPPPPQPARSASSSTINLMVSTEPLALTE
Sbjct: 2843 LAGQTYHVAVVCYLRSQVRATYHGSFSTKKSQPPPPQPARSASSSTINLMVSTEPLALTE 2902

Query: 3109 TDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAK 3168
            TDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAK
Sbjct: 2903 TDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAK 2962

Query: 3169 PGVISVMGT 3177
            PGVISVMGT
Sbjct: 2963 PGVISVMGT 2971



 Score = 1036 bits (2680), Expect = 0.0
 Identities = 618/1672 (36%), Positives = 958/1672 (57%), Gaps = 57/1672 (3%)

Query: 1    MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVRE 60
            MRKHRHLPLVAVFCLFLSGFPTTHAQQQQA      +ADIIFL+D S   G  +F ++ +
Sbjct: 1    MRKHRHLPLVAVFCLFLSGFPTTHAQQQQAAQD---SADIIFLIDGSNNTGSVNFAVILD 57

Query: 61   FLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGG-TNQTG 119
            FL ++++ L +G       +VQF+  P T F L+TY TK +VL  +  + + GG     G
Sbjct: 58   FLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIG 117

Query: 120  KGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVED 179
              L++++++H T+A GSR  +GVPQV+V+++ G S D +      LK A V  F +G + 
Sbjct: 118  LALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQA 177

Query: 180  ADEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETL-KDITAQ 238
            A    L+ IA++  +  +F +  F S  D+   L+  +             T+   +   
Sbjct: 178  ASRAELQHIATD--DNLVFTVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEV 235

Query: 239  DSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDT 298
            +  DI+FL+DGS+  G  NF  I DF+  ++++L IG   I+V V Q++D  R  F  +T
Sbjct: 236  NKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNT 295

Query: 299  YSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPS 358
            + TK +V+ AV+ +    G     G ALDFV  N FT + G R  EG+P++LVLI+ G S
Sbjct: 296  HPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKS 355

Query: 359  SDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPY 418
             DEI      LK++S+ +F +G + A +AEL+ IA D +LVF   EFR+   LQ  +LP 
Sbjct: 356  LDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRA-APLQ-GMLPG 413

Query: 419  IVGVAQRHIVLKPPTIVTQVIEV--NKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLE 476
            +         L P   ++   EV  NKRDI+FL+DGS+ +G  NF  +RDF+  ++  L+
Sbjct: 414  L---------LAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD 464

Query: 477  IGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNL 536
            IG D I+V + Q++DT   EF  NT+ TK +++  +R+++   GS L TGSAL +V  N 
Sbjct: 465  IGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANH 524

Query: 537  FTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIA 596
            FT + G R  E +P+LL+L+T G+S D   Q A  L R+ I+ F +G   A++AELE+IA
Sbjct: 525  FTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIA 584

Query: 597  FDSSLVFIPAEFRAAPLQGMLPGLLAPLRTL--SGTPEV----HSNKRDIIFLLDGSAN- 649
            F+ SLV++  +F + P   +   L+ PL T    G  EV      +KRDI+FL DGSAN 
Sbjct: 585  FNPSLVYLMDDFSSLP--ALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANL 642

Query: 650  VGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQL 709
            VG+  FP VRDF+  +++ L++  +  R+ + Q+SD    E   + +Q+K +IL  ++++
Sbjct: 643  VGQ--FPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRM 700

Query: 710  QLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRA 769
            +++ G  LN G AL Y     F ++ GSRI + V Q L+LL AG+S D     A+ L ++
Sbjct: 701  KIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQS 760

Query: 770  GILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPL 829
            G++ F   A  A+ AELEQI  +P+ +   +    +  L  Q++  L +  +G    V  
Sbjct: 761  GVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPV-- 818

Query: 830  AQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESR 889
                 ++D++FL DGS  +   FP++++F+ ++++ L+V  +  R+AV QYSD  + E  
Sbjct: 819  ---SGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFY 875

Query: 890  FDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVA 949
             + + +K +++N V+++ +  G   N G AL++  R I V SAGSRI +GV Q L++L A
Sbjct: 876  LNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTA 935

Query: 950  GRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQI 1009
             RS D V  P+  +K+ G VP      NAD  E++ I   P F +A  +  ++G +   I
Sbjct: 936  DRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVI 995

Query: 1010 -----------VNLLKSVHNGAPAP-VSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVES 1057
                       ++ L+ V    P+P V G++DVVFL+DGS+     F  ++  ++R+V+ 
Sbjct: 996  SERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDY 1055

Query: 1058 LDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLR 1117
            LDVG D  RVAV+Q+SD  + EF LN++ +K +V NAV++L   GG   N G ALE+V R
Sbjct: 1056 LDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSR 1115

Query: 1118 NILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQT 1177
            NI     GSRI EGVPQ L+++++ +S D+V +P+V +K+ G  P  I   NAD  E+  
Sbjct: 1116 NIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIA-RNADQEELVK 1174

Query: 1178 ISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFL 1237
            IS  P++  ++ TFR+L +++Q +   +T LT E++ +L    +  P        D+VFL
Sbjct: 1175 ISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFL 1234

Query: 1238 IDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQ 1296
            ID S+   P+ F ++R  + R+V  L++G    RV V+QFS+D   EF L  + S+  V 
Sbjct: 1235 IDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVL 1294

Query: 1297 NAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPA 1356
            +A++RLR +GG  +N G ALE+V+RN+F +  GSRIE+GVPQ LVL+  GKS D+V   A
Sbjct: 1295 DAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFA 1354

Query: 1357 VELKQFGVAPFTIA-RNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQ 1415
              ++  G+    +  RN D+ EL  I+  P  VF+V  FRELP++E++++       +  
Sbjct: 1355 QVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATP 1414

Query: 1416 IQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRV 1475
                + +   PP   E   ADIVFL+D S   R D F  +  FVS IV  +      ++V
Sbjct: 1415 APPGVDTP--PPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQV 1472

Query: 1476 GVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSR 1535
            G+VQ+++D   EF+LK + ++  ++DAI ++  +GG   NT   LE +  N FV  AGSR
Sbjct: 1473 GLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSR 1532

Query: 1536 IEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFT 1595
            ++  VPQ   ++ GGKS +D    +  +   G+    VG RNID  E+  I ++    F 
Sbjct: 1533 LDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFR 1592

Query: 1596 VREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGS 1647
            V   +EL  + E+++ +   +      PGV        +    D++   DGS
Sbjct: 1593 VGNVQELSELSEQVLETLHDAMHETLCPGV----TDAAKACNLDVILGFDGS 1640



 Score =  672 bits (1733), Expect = 0.0
 Identities = 419/1263 (33%), Positives = 680/1263 (53%), Gaps = 79/1263 (6%)

Query: 17   LSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDF 76
            LSG P  H+ ++          DIIFL+D S  +G+ +F  VR+F+ ++V SL +G ++ 
Sbjct: 421  LSGTPEVHSNKR----------DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNI 470

Query: 77   HFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTN-QTGKGLEYIMQSHLTKAAG 135
               LVQF+  P TEF LNTY+TK ++L H+  +   GG+   TG  L Y+  +H T+A G
Sbjct: 471  RVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGG 530

Query: 136  SRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNM 195
            SR  + VPQ++++LT G S+D     +  L  A +  F +G   A++  L++IA  P  +
Sbjct: 531  SRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLV 590

Query: 196  HMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGS 255
            ++  +++F+SL  +   L+  + + VS    G  E +     +   DI+FL DGS N   
Sbjct: 591  YL--MDDFSSLPALPQQLIQPLTTYVS----GGVEEVPLAQPESKRDILFLFDGSANLVG 644

Query: 256  VNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFA 315
              F V+ DFL  ++++L +  +  R+ V Q+SD+ +     D + +K ++L  VK +   
Sbjct: 645  -QFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIK 703

Query: 316  GGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVF 375
             G+  N+G ALD+     F ++ GSR+E+GV Q LVL+ AG SSD +      LKQ+ V 
Sbjct: 704  TGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVV 763

Query: 376  SFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIV 435
             F   A+ A  AEL+ I      +         GDL  +++  +  V   H     P   
Sbjct: 764  PFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSV---HNGAPAPV-- 818

Query: 436  TQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRP 495
                   ++D+VFL+DGS  +  + F  +++F+ +V++ L++GQD ++VAV QY+D  RP
Sbjct: 819  -----SGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRP 872

Query: 496  EFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVL 555
            EFY N++  K++V+ AVR++  L G    TG+AL+FV  N+  SSAG R  EG+P+LL++
Sbjct: 873  EFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIV 932

Query: 556  ITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAF-DSSLVFIPAEFRAAPLQ 614
            +T  +S D++  P+  +KR   +   IG   AD  E++ I+F     V IP   +   +Q
Sbjct: 933  LTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQ 992

Query: 615  GMLP-----------GLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVM 663
             ++              L P+     +P V   KRD++FL+DGS + G   F YVR  + 
Sbjct: 993  QVISERVTQLTREELSRLQPVLQPLPSPGV-GGKRDVVFLIDGSQSAG-PEFQYVRTLIE 1050

Query: 664  NLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSAL 723
             LV+ LD+G D  RV ++QFSD P  EF LN + +K ++   +++L+ +GG  +N G+AL
Sbjct: 1051 RLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNAL 1110

Query: 724  SYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANK 783
             YV  N F    GSRI E VPQ L+L+++G+S+D     A  L + G+  F + A  A++
Sbjct: 1111 EYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI-ARNADQ 1169

Query: 784  AELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEV-------PLAQPESKR 836
             EL +I+ +P  V+ +  F  LP+L Q+L+ P+TT  S  ++++       P A      
Sbjct: 1170 EELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAA 1229

Query: 837  DILFLFDGSANL-VGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQS 895
            DI+FL D S  +    F  +RDF+ +I+  LN+ P   R+ V Q+S+DV  E     ++S
Sbjct: 1230 DIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRS 1289

Query: 896  KPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDR 955
            +  +L+ ++R++++ G  LN G AL++  R +FVKSAGSRIEDGV Q LVL++ G+S D 
Sbjct: 1290 QAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDD 1349

Query: 956  VDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLL-K 1014
            V   A  ++ SG+V      +N D  EL+ I   P  +       ++ ++  +I+N    
Sbjct: 1350 VSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGP 1409

Query: 1015 SVHNGAP---------APVSGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDR 1064
            S    AP          P   + D+VFLLDGS    R  F  +  FV  +V+++    D 
Sbjct: 1410 SAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDS 1469

Query: 1065 VRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSA 1124
            ++V +VQY+     EF+L  +  K+ +++A+ ++   GG   NT   LE +  N  V  A
Sbjct: 1470 IQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEA 1529

Query: 1125 GSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDF 1184
            GSR+ + VPQ+  V+T  +S +D ++ S+ + + G     +G+ N D  E+  I      
Sbjct: 1530 GSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKI------ 1583

Query: 1185 AVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGV-----GGKRDVVFLID 1239
            A    T  ++G VQ+     +++L+ + L  L   +     PGV         DV+   D
Sbjct: 1584 ASNSATAFRVGNVQE-----LSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFD 1638

Query: 1240 GSQ 1242
            GS+
Sbjct: 1639 GSR 1641


>gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo
            sapiens]
          Length = 2570

 Score = 4815 bits (12490), Expect = 0.0
 Identities = 2432/2562 (94%), Positives = 2475/2562 (96%), Gaps = 19/2562 (0%)

Query: 627  LSGTPEVHS---------NKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIR 677
            LSG P  H+         NKRDI+FL+DGS+ +G  NF  +RDF+  ++  L+IG D I+
Sbjct: 17   LSGFPTTHAQQQQAVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQ 76

Query: 678  VGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGS 737
            V + Q++DT   EF  NT+ TK +++  +R+++   GS L TGSAL +V  N FT + G 
Sbjct: 77   VAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGY 136

Query: 738  RIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVY 797
            R  E +P+LL+L+T G+S D   Q A  L R+ I+ F +G   A++AELE+IAF+ SLV+
Sbjct: 137  RAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVF 196

Query: 798  LMDDFSSLP--ALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANLVGQFPVV 855
            +  +F + P   +   L+ PL T +SG  EE       SKRDILFLFDGSANLVGQFPVV
Sbjct: 197  IPAEFRAAPLQGMLPGLLAPLRT-LSGTPEE-------SKRDILFLFDGSANLVGQFPVV 248

Query: 856  RDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALN 915
            RDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALN
Sbjct: 249  RDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALN 308

Query: 916  LGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQA 975
            LGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQA
Sbjct: 309  LGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQA 368

Query: 976  KNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLD 1035
            KNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLD
Sbjct: 369  KNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLD 428

Query: 1036 GSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAV 1095
            GSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAV
Sbjct: 429  GSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAV 488

Query: 1096 RQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVV 1155
            RQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVV
Sbjct: 489  RQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVV 548

Query: 1156 KRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSR 1215
            KRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSR
Sbjct: 549  KRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSR 608

Query: 1216 LQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQ 1275
            LQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQ
Sbjct: 609  LQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQ 668

Query: 1276 FSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEG 1335
            FSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEG
Sbjct: 669  FSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEG 728

Query: 1336 VPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVKISLSPEYVFSVSTFR 1395
            VPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVKISLSPEYVFSVSTFR
Sbjct: 729  VPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVKISLSPEYVFSVSTFR 788

Query: 1396 ELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHI 1455
            ELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHI
Sbjct: 789  ELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHI 848

Query: 1456 RDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLN 1515
            RDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLN
Sbjct: 849  RDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLN 908

Query: 1516 TGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGD 1575
            TGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGD
Sbjct: 909  TGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGD 968

Query: 1576 RNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEK 1635
            RNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEK
Sbjct: 969  RNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEK 1028

Query: 1636 KKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKD 1695
            KKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKD
Sbjct: 1029 KKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKD 1088

Query: 1696 FSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKS 1755
            FSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKS
Sbjct: 1089 FSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKS 1148

Query: 1756 VEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLET 1815
            VEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLET
Sbjct: 1149 VEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLET 1208

Query: 1816 LHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFESKVDAILNRISQMHRV 1875
            LHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFESKVDAILNRISQMHRV
Sbjct: 1209 LHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFESKVDAILNRISQMHRV 1268

Query: 1876 SCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQHPYVLTEDTLKVYLN 1935
            SCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQHPYVLTEDTLKVYLN
Sbjct: 1269 SCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQHPYVLTEDTLKVYLN 1328

Query: 1936 KFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILVGLERVVNLERLMHLE 1995
            KFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILVGLERVVNLERLMHLE
Sbjct: 1329 KFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILVGLERVVNLERLMHLE 1388

Query: 1996 FGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQRGDRGPIGSIGPKGIP 2055
            FGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQRGDRGPIGSIGPKGIP
Sbjct: 1389 FGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQRGDRGPIGSIGPKGIP 1448

Query: 2056 GEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLD 2115
            GEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLD
Sbjct: 1449 GEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLD 1508

Query: 2116 GEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGD 2175
            GEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGD
Sbjct: 1509 GEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGD 1568

Query: 2176 LGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGP 2235
            LGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGP
Sbjct: 1569 LGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGP 1628

Query: 2236 AGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGD 2295
            AGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGD
Sbjct: 1629 AGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGD 1688

Query: 2296 DGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
            DGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK
Sbjct: 1689 DGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 1748

Query: 2356 GDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVNQ 2415
            GDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVNQ
Sbjct: 1749 GDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVNQ 1808

Query: 2416 DTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFADSKRKSVLLDKIKN 2475
            DTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFADSKRKSVLLDKIKN
Sbjct: 1809 DTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFADSKRKSVLLDKIKN 1868

Query: 2476 LQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTRASPQLREAVLKLSD 2535
            LQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTRASPQLREAVLKLSD
Sbjct: 1869 LQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTRASPQLREAVLKLSD 1928

Query: 2536 AGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLENVLTCHVCLDICNIDP 2595
            AGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLENVLTCHVCLDICNIDP
Sbjct: 1929 AGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLENVLTCHVCLDICNIDP 1988

Query: 2596 SCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDP 2655
            SCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDP
Sbjct: 1989 SCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDP 2048

Query: 2656 KASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRAL 2715
            KASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRAL
Sbjct: 2049 KASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRAL 2108

Query: 2716 GSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIG 2775
            GSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIG
Sbjct: 2109 GSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIG 2168

Query: 2776 RKVNIKEVYTFASEPNDVFFKLVDKSTELNEEPLMRFGRLLPSFVSSENAFYLSPDIRKQ 2835
            RKVNIKEVYTFASEPNDVFFKLVDKSTELNEEPLMRFGRLLPSFVSSENAFYLSPDIRKQ
Sbjct: 2169 RKVNIKEVYTFASEPNDVFFKLVDKSTELNEEPLMRFGRLLPSFVSSENAFYLSPDIRKQ 2228

Query: 2836 CDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTSNPVTTTKPVTTTKPVTTTTKPVTTTTK 2895
            CDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTSNPVTTTKPVTTTKPVTTTTKPVTTTTK
Sbjct: 2229 CDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTSNPVTTTKPVTTTKPVTTTTKPVTTTTK 2288

Query: 2896 PVTIINQPSVKPAAAKPAPAKPVAAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPP 2955
            PVTIINQPSVKPAAAKPAPAKPVAAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPP
Sbjct: 2289 PVTIINQPSVKPAAAKPAPAKPVAAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPP 2348

Query: 2956 AAAAAKPVATKPEVPRPQAAKPAATKPATTKPMVKMSREVQVFEITENSAKLHWERAEPP 3015
            AAAAAKPVATKPEVPRPQAAKPAATKPATTKPMVKMSREVQVFEITENSAKLHWERAEPP
Sbjct: 2349 AAAAAKPVATKPEVPRPQAAKPAATKPATTKPMVKMSREVQVFEITENSAKLHWERAEPP 2408

Query: 3016 GPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGLLAGQTYHVAVVCYLRSQVRATYHGSFS 3075
            GPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGLLAGQTYHVAVVCYLRSQVRATYHGSFS
Sbjct: 2409 GPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGLLAGQTYHVAVVCYLRSQVRATYHGSFS 2468

Query: 3076 TKKSQPPPPQPARSASSSTINLMVSTEPLALTETDICKLPKDEGTCRDFILKWYYDPNTK 3135
            TKKSQPPPPQPARSASSSTINLMVSTEPLALTETDICKLPKDEGTCRDFILKWYYDPNTK
Sbjct: 2469 TKKSQPPPPQPARSASSSTINLMVSTEPLALTETDICKLPKDEGTCRDFILKWYYDPNTK 2528

Query: 3136 SCARFWYGGCGGNENKFGSQKECEKVCAPVLAKPGVISVMGT 3177
            SCARFWYGGCGGNENKFGSQKECEKVCAPVLAKPGVISVMGT
Sbjct: 2529 SCARFWYGGCGGNENKFGSQKECEKVCAPVLAKPGVISVMGT 2570



 Score =  988 bits (2553), Expect = 0.0
 Identities = 560/1225 (45%), Positives = 778/1225 (63%), Gaps = 31/1225 (2%)

Query: 438  VIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEF 497
            VIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEF
Sbjct: 31   VIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEF 90

Query: 498  YFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLIT 557
            YFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLIT
Sbjct: 91   YFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLIT 150

Query: 558  GGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGML 617
            GGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGML
Sbjct: 151  GGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGML 210

Query: 618  PGLLAPLRTLSGTPEVHSNKRDIIFLLDGSAN-VGKTNFPYVRDFVMNLVNSLDIGNDNI 676
            PGLLAPLRTLSGTPE   +KRDI+FL DGSAN VG+  FP VRDF+  +++ L++  +  
Sbjct: 211  PGLLAPLRTLSGTPE--ESKRDILFLFDGSANLVGQ--FPVVRDFLYKIIDELNVKPEGT 266

Query: 677  RVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGG 736
            R+ + Q+SD    E   + +Q+K +IL  +++++++ G  LN G AL Y     F ++ G
Sbjct: 267  RIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAG 326

Query: 737  SRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLV 796
            SRI + V Q L+LL AG+S D     A+ L ++G++ F   A  A+ AELEQI  +P+ +
Sbjct: 327  SRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFI 386

Query: 797  YLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANLVGQFPVVR 856
               +    +  L  Q++  L +  +G    V       ++D++FL DGS  +   FP+++
Sbjct: 387  LAAESLPKIGDLHPQIVNLLKSVHNGAPAPV-----SGEKDVVFLLDGSEGVRSGFPLLK 441

Query: 857  DFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNL 916
            +F+ ++++ L+V  +  R+AV QYSD  + E   + + +K +++N V+++ +  G   N 
Sbjct: 442  EFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNT 501

Query: 917  GYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAK 976
            G AL++  R I V SAGSRI +GV Q L++L A RS D V  P+  +K+ G VP      
Sbjct: 502  GAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIG 561

Query: 977  NADPAELEQIVLSPAFILAAESLPKIGDLHPQI-----------VNLLKSVHNGAPAP-V 1024
            NAD  E++ I   P F +A  +  ++G +   I           ++ L+ V    P+P V
Sbjct: 562  NADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGV 621

Query: 1025 SGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNS 1084
             G++DVVFL+DGS+     F  ++  ++R+V+ LDVG D  RVAV+Q+SD  + EF LN+
Sbjct: 622  GGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 681

Query: 1085 YMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRS 1144
            + +K +V NAV++L   GG   N G ALE+V RNI     GSRI EGVPQ L+++++ +S
Sbjct: 682  HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKS 741

Query: 1145 GDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISER 1204
             D+V +P+V +K+ G  P  I   NAD  E+  IS  P++  ++ TFR+L +++Q +   
Sbjct: 742  DDEVDDPAVELKQFGVAPFTIA-RNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTP 800

Query: 1205 VTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLD 1263
            +T LT E++ +L    +  P        D+VFLID S+   P+ F ++R  + R+V  L+
Sbjct: 801  ITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLN 860

Query: 1264 VGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNI 1323
            +G    RV V+QFS+D   EF L  + S+  V +A++RLR +GG  +N G ALE+V+RN+
Sbjct: 861  IGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNL 920

Query: 1324 FKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIA-RNADQEELVKIS 1382
            F +  GSRIE+GVPQ LVL+  GKS D+V   A  ++  G+    +  RN D+ EL  I+
Sbjct: 921  FVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTIT 980

Query: 1383 LSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLID 1442
              P  VF+V  FRELP++E++++       +      + +   PP   E   ADIVFL+D
Sbjct: 981  NDPRLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDTP--PPSRPEKKKADIVFLLD 1038

Query: 1443 SSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDA 1502
             S   R D F  +  FVS IV  +      ++VG+VQ+++D   EF+LK + ++  ++DA
Sbjct: 1039 GSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDA 1098

Query: 1503 IRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQV 1562
            I ++  +GG   NT   LE +  N FV  AGSR++  VPQ   ++ GGKS +D    +  
Sbjct: 1099 INKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLA 1158

Query: 1563 IRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAP 1622
            +   G+    VG RNID  E+  I ++    F V   +EL  + E+++ +   +      
Sbjct: 1159 LTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLETLHDAMHETLC 1218

Query: 1623 PGVDTPPPSRPEKKKADIVFLLDGS 1647
            PGV        +    D++   DGS
Sbjct: 1219 PGV----TDAAKACNLDVILGFDGS 1239



 Score =  763 bits (1970), Expect = 0.0
 Identities = 462/1189 (38%), Positives = 686/1189 (57%), Gaps = 45/1189 (3%)

Query: 242  DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 301
            DI+FL+DGS+  G  NF  I DF+  ++++L IG   I+V V Q++D  R  F  +T+ T
Sbjct: 38   DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 97

Query: 302  KAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDE 361
            K +V+ AV+ +    G     G ALDFV  N FT + G R  EG+P++LVLI+ G S DE
Sbjct: 98   KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDE 157

Query: 362  IRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIVG 421
            I      LK++S+ +F +G + A +AEL+ IA D +LVF   EFR+   LQ  +LP +  
Sbjct: 158  ISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRA-APLQ-GMLPGL-- 213

Query: 422  VAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDL 481
                   L P   ++   E +KRDI+FL DGS+ L +  F  +RDF+ K+I  L +  + 
Sbjct: 214  -------LAPLRTLSGTPEESKRDILFLFDGSANL-VGQFPVVRDFLYKIIDELNVKPEG 265

Query: 482  IQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSA 541
             ++AVAQY+D V+ E  F+ H +K E++  V++MK   G AL  G ALD+ +  +F  SA
Sbjct: 266  TRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSA 325

Query: 542  GYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSL 601
            G R  +G+ + LVL+  G+S D +  PA  LK+S ++ F    K AD AELE+I    S 
Sbjct: 326  GSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVL--SP 383

Query: 602  VFIPAEFRAAPLQGMLPGLLAPLRTL-SGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRD 660
             FI A      +  + P ++  L+++ +G P   S ++D++FLLDGS  V ++ FP +++
Sbjct: 384  AFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGV-RSGFPLLKE 442

Query: 661  FVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTG 720
            FV  +V SLD+G D +RV +VQ+SD    EF LN+Y  K D++  +RQL L GG   NTG
Sbjct: 443  FVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTG 502

Query: 721  SALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQ 780
            +AL +V  N    + GSRI E VPQLL++LTA +S D     +  + R G +   +G   
Sbjct: 503  AALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGN 562

Query: 781  ANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEV-PLAQP------E 833
            A+  E++ I+F P     +  F  L  + Q + + +T      +  + P+ QP       
Sbjct: 563  ADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVG 622

Query: 834  SKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEH 893
             KRD++FL DGS +   +F  VR  + +++D L+V  + TR+AV Q+SDD KVE   + H
Sbjct: 623  GKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAH 682

Query: 894  QSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSS 953
             SK E+ N V+R++ K G+ +N+G AL+Y  R IF +  GSRIE+GV QFLVL+ +G+S 
Sbjct: 683  SSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSD 742

Query: 954  DRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLH------- 1006
            D VD PA  LKQ GV PF   A+NAD  EL +I LSP ++ +  +  ++  L        
Sbjct: 743  DEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPI 801

Query: 1007 -----PQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVR-SGFPLLKEFVQRVVESLDV 1060
                  QI  LL S     PA  S   D+VFL+D SEGVR  GF  +++FV R+V  L++
Sbjct: 802  TTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNI 861

Query: 1061 GQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNIL 1120
            G  +VRV VVQ+S+   PEFYL +Y ++  V++A+R+L L GG   NTG ALEFV RN+ 
Sbjct: 862  GPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLF 921

Query: 1121 VSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISF 1180
            V SAGSRI +GVPQ L+++   +S DDV   + V++  G V +G+G  N D TE+QTI+ 
Sbjct: 922  VKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITN 981

Query: 1181 IPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQP--VLQPLPSPGVGGKRDVVFLI 1238
             P     +  FR+L  ++    ER+        +   P  V  P PS     K D+VFL+
Sbjct: 982  DPRLVFTVREFRELPNIE----ERIMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLL 1037

Query: 1239 DGS-QSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQN 1297
            DGS       FQ V   +  +VD +    D+ +V ++Q++ DP  EF L   S+K ++ +
Sbjct: 1038 DGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIID 1097

Query: 1298 AVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAV 1357
            A+ ++  KGGR  N    LE++  N F    GSR+++ VPQ   +I+ GKS ++  D ++
Sbjct: 1098 AINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSL 1157

Query: 1358 ELKQFGVAPFTI-ARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLL 1405
             L Q GV  F +  RN D EE+ KI+ +    F V   +EL  L +++L
Sbjct: 1158 ALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVL 1206



 Score =  705 bits (1820), Expect = 0.0
 Identities = 436/1279 (34%), Positives = 694/1279 (54%), Gaps = 76/1279 (5%)

Query: 1    MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVRE 60
            MRKHRHLPLVAVFCLFLSGFPTTHAQQQQA ++     DI+FLVD S  +G  +F  +R+
Sbjct: 1    MRKHRHLPLVAVFCLFLSGFPTTHAQQQQAVIEVN-KRDIVFLVDGSSALGLANFNAIRD 59

Query: 61   FLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTN-QTG 119
            F+  V++ L +G++    A+ Q+      EF  NT+ TK+EV++ +  M  + G+   TG
Sbjct: 60   FIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTG 119

Query: 120  KGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVED 179
              L+++  +  T +AG RA +G+P+++V++T G S D ++ P+ ELK + +  FAIG + 
Sbjct: 120  SALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKG 179

Query: 180  ADEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQD 239
            AD+  L+EIA +            +SL  I     +     + P       TL     + 
Sbjct: 180  ADQAELEEIAFD------------SSLVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEES 227

Query: 240  SADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTY 299
              DI+FL DGS N     F V+ DFL  ++++L +  +  R+ V Q+SD+ +     D +
Sbjct: 228  KRDILFLFDGSANLVG-QFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEH 286

Query: 300  STKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSS 359
             +K ++L  VK +    G+  N+G ALD+     F ++ GSR+E+GV Q LVL+ AG SS
Sbjct: 287  QSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSS 346

Query: 360  DEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYI 419
            D +      LKQ+ V  F   A+ A  AEL+ I      +         GDL  +++  +
Sbjct: 347  DRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLL 406

Query: 420  VGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQ 479
              V   H     P          ++D+VFL+DGS  +  + F  +++F+ +V++ L++GQ
Sbjct: 407  KSV---HNGAPAPV-------SGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQ 455

Query: 480  DLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTS 539
            D ++VAV QY+D  RPEFY N++  K++V+ AVR++  L G    TG+AL+FV  N+  S
Sbjct: 456  DRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVS 515

Query: 540  SAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAF-D 598
            SAG R  EG+P+LL+++T  +S D++  P+  +KR   +   IG   AD  E++ I+F  
Sbjct: 516  SAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIP 575

Query: 599  SSLVFIPAEFRAAPLQGMLP-----------GLLAPLRTLSGTPEVHSNKRDIIFLLDGS 647
               V IP   +   +Q ++              L P+     +P V   KRD++FL+DGS
Sbjct: 576  DFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGV-GGKRDVVFLIDGS 634

Query: 648  ANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLR 707
             + G   F YVR  +  LV+ LD+G D  RV ++QFSD P  EF LN + +K ++   ++
Sbjct: 635  QSAG-PEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQ 693

Query: 708  QLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALT 767
            +L+ +GG  +N G+AL YV  N F    GSRI E VPQ L+L+++G+S+D     A  L 
Sbjct: 694  RLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELK 753

Query: 768  RAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEV 827
            + G+  F + A  A++ EL +I+ +P  V+ +  F  LP+L Q+L+ P+TT  S  ++++
Sbjct: 754  QFGVAPFTI-ARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKL 812

Query: 828  -------PLAQPESKRDILFLFDGSANL-VGQFPVVRDFLYKIIDELNVKPEGTRIAVAQ 879
                   P A      DI+FL D S  +    F  +RDF+ +I+  LN+ P   R+ V Q
Sbjct: 813  LASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQ 872

Query: 880  YSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDG 939
            +S+DV  E     ++S+  +L+ ++R++++ G  LN G AL++  R +FVKSAGSRIEDG
Sbjct: 873  FSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDG 932

Query: 940  VLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESL 999
            V Q LVL++ G+S D V   A  ++ SG+V      +N D  EL+ I   P  +      
Sbjct: 933  VPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREF 992

Query: 1000 PKIGDLHPQIVNLL-KSVHNGAP---------APVSGEKDVVFLLDGSEGV-RSGFPLLK 1048
             ++ ++  +I+N    S    AP          P   + D+VFLLDGS    R  F  + 
Sbjct: 993  RELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVL 1052

Query: 1049 EFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNT 1108
             FV  +V+++    D ++V +VQY+     EF+L  +  K+ +++A+ ++   GG   NT
Sbjct: 1053 RFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANT 1112

Query: 1109 GAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIG 1168
               LE +  N  V  AGSR+ + VPQ+  V+T  +S +D ++ S+ + + G     +G+ 
Sbjct: 1113 KVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVR 1172

Query: 1169 NADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGV 1228
            N D  E+  I      A    T  ++G VQ+     +++L+ + L  L   +     PGV
Sbjct: 1173 NIDSEEVGKI------ASNSATAFRVGNVQE-----LSELSEQVLETLHDAMHETLCPGV 1221

Query: 1229 -----GGKRDVVFLIDGSQ 1242
                     DV+   DGS+
Sbjct: 1222 TDAAKACNLDVILGFDGSR 1240



 Score =  315 bits (807), Expect = 5e-85
 Identities = 226/735 (30%), Positives = 363/735 (49%), Gaps = 46/735 (6%)

Query: 35   GAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLN 94
            G   D++FL+D S + G E FQ VR  +  +V  L VG +    A++QF+ +P  EFLLN
Sbjct: 622  GGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLN 680

Query: 95   TYRTKQEVLSHISNMSYIGGTN-QTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGH 153
             + +K EV + +  +   GG     G  LEY+ ++   +  GSR  +GVPQ +V+++ G 
Sbjct: 681  AHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGK 740

Query: 154  SKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDIVGNL 213
            S D +  P+ ELK   V  F I   +AD+  L +I+  P   ++F++  F  L  +   L
Sbjct: 741  SDDEVDDPAVELKQFGVAPFTIA-RNADQEELVKISLSP--EYVFSVSTFRELPSLEQKL 797

Query: 214  VSCVHSSVSPE---RAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLE 270
            ++ + +  S +       T         D+ADI+FLID S       FA I DF+  ++ 
Sbjct: 798  LTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVR 857

Query: 271  KLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVV 330
            +L IG  ++RVGVVQFS++    F L TY ++A VL A++ L   GG   N G AL+FV 
Sbjct: 858  RLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVA 917

Query: 331  ENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQ 390
             N F ++ GSR+E+GVPQ LVL+  G S D++      ++ + + S G+G +   R ELQ
Sbjct: 918  RNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQ 977

Query: 391  HIATDDNLVFTVPEFRSFGDLQEKLL----PYIVGVAQRHIVLKPPTIVTQVIEVNKRDI 446
             I  D  LVFTV EFR   +++E+++    P     A   +   PP+      E  K DI
Sbjct: 978  TITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRP----EKKKADI 1033

Query: 447  VFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKR 506
            VFL+DGS      +F  +  F+++++  +    D IQV + QY      EF+     TKR
Sbjct: 1034 VFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKR 1093

Query: 507  EVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEIS 566
            ++I A+ K+    G    T   L+ +R N F   AG R  + +P++  +ITGGKS+++  
Sbjct: 1094 QIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQ 1153

Query: 567  QPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRT 626
              +  L +  +  FA+G +  D  E+ +IA +S+       FR   +Q +       L T
Sbjct: 1154 DVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSA-----TAFRVGNVQELSELSEQVLET 1208

Query: 627  LSG----------TPEVHSNKRDIIFLLDGSAN----VGKTNFPYVRDFVMNLVNSLDI- 671
            L            T    +   D+I   DGS +    V +  F    D ++N ++ +   
Sbjct: 1209 LHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFESKVDAILNRISQMHRV 1268

Query: 672  -----GNDNIRVGLVQFSDT-PVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSY 725
                  +  +RV +V  + + PV  F  + YQ   ++L   R ++ Q    L   +    
Sbjct: 1269 SCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQ--PEMLEKFRNMRSQHPYVLTEDTL--K 1324

Query: 726  VYANHFTEAGGSRIR 740
            VY N F ++    ++
Sbjct: 1325 VYLNKFRQSSPDSVK 1339



 Score = 58.9 bits (141), Expect = 8e-08
 Identities = 81/370 (21%), Positives = 155/370 (41%), Gaps = 52/370 (14%)

Query: 242  DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQI----RVGVVQFSDEPRTMFSLD 297
            ++ F +D S       F  + D +++++  L I         RV VV +++E  T     
Sbjct: 1795 ELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 1854

Query: 298  TYSTKAQVLGAVKALGFA-GGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAG 356
                K+ +L  +K L  A   +  ++  A+ FV  N F R     +   + +V V  S  
Sbjct: 1855 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFL---MRKVAVFFSNT 1911

Query: 357  PS--SDEIRYGVVALKQASVFSFGL----GAQAASRAELQHIATDDNLVFTVPEFRSFGD 410
            P+  S ++R  V+ L  A +    L      Q  +  ++ + A    LV  +P  R   D
Sbjct: 1912 PTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALV--LPAGRDLTD 1969

Query: 411  LQEKLLPYIV-----------GVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLA 459
              E +L   V           G        +        +++   D+ F++D +    L 
Sbjct: 1970 FLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDI---DMAFILDSAETTTLF 2026

Query: 460  NFNAIRDFIAKVIQRLEIGQD------LIQVAVAQYADT----------VRPEFYFNTHP 503
             FN ++ +IA ++++L++  D        +VAV Q+A +          V+ EF    + 
Sbjct: 2027 QFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYG 2086

Query: 504  TKREVITAV-RKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSL 562
            +K +++  + R M  L G+    GSA+++   N+F S+   R      K++VL+  G+  
Sbjct: 2087 SKEKLVDFLSRGMTQLQGTRA-LGSAIEYTIENVFESAPNPRDL----KIVVLMLTGEVP 2141

Query: 563  DEISQPAQEL 572
            ++  + AQ +
Sbjct: 2142 EQQLEEAQRV 2151


>gi|240255540 alpha 3 type VI collagen isoform 3 precursor [Homo
            sapiens]
          Length = 1237

 Score = 2293 bits (5942), Expect = 0.0
 Identities = 1195/1210 (98%), Positives = 1200/1210 (99%), Gaps = 1/1210 (0%)

Query: 229  TETLKDITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSD 288
            T   +   AQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSD
Sbjct: 23   THAQQQQAAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSD 82

Query: 289  EPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQ 348
            EPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQ
Sbjct: 83   EPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQ 142

Query: 349  VLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSF 408
            VLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSF
Sbjct: 143  VLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSF 202

Query: 409  GDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFI 468
            GDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFI
Sbjct: 203  GDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFI 262

Query: 469  AKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSA 528
            AKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSA
Sbjct: 263  AKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSA 322

Query: 529  LDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGAD 588
            LDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGAD
Sbjct: 323  LDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGAD 382

Query: 589  QAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSA 648
            QAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSA
Sbjct: 383  QAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSA 442

Query: 649  NVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQ 708
            NVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQ
Sbjct: 443  NVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQ 502

Query: 709  LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTR 768
            LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTR
Sbjct: 503  LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTR 562

Query: 769  AGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVP 828
            AGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVP
Sbjct: 563  AGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVP 622

Query: 829  LAQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVES 888
            LAQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVES
Sbjct: 623  LAQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVES 682

Query: 889  RFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLV 948
            RFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLV
Sbjct: 683  RFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLV 742

Query: 949  AGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQ 1008
            AGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQ
Sbjct: 743  AGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQ 802

Query: 1009 IVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVA 1068
            IVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVA
Sbjct: 803  IVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVA 862

Query: 1069 VVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRI 1128
            VVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRI
Sbjct: 863  VVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRI 922

Query: 1129 TEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAI 1188
            TEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAI
Sbjct: 923  TEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAI 982

Query: 1189 PTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEF 1248
            PTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEF
Sbjct: 983  PTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEF 1042

Query: 1249 QYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGR 1308
            QYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGR
Sbjct: 1043 QYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGR 1102

Query: 1309 QINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFT 1368
            QINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFT
Sbjct: 1103 QINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFT 1162

Query: 1369 IARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPP 1428
            IARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPP
Sbjct: 1163 IARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPP 1222

Query: 1429 AVESDAADIV 1438
              E  A++++
Sbjct: 1223 G-EMGASEVL 1231



 Score =  797 bits (2059), Expect = 0.0
 Identities = 476/1212 (39%), Positives = 703/1212 (58%), Gaps = 54/1212 (4%)

Query: 627  LSGTPEVHSNKR-------DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVG 679
            LSG P  H+ ++       DIIFL+DGS N G  NF  + DF++NL+  L IG   IRVG
Sbjct: 17   LSGFPTTHAQQQQAAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVG 76

Query: 680  LVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRI 739
            +VQFSD P T FSL+TY TK+ +LG ++ L   GG   N G AL +V  NHFT AGGSR+
Sbjct: 77   VVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRV 136

Query: 740  REHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLM 799
             E VPQ+L+L++AG S D       AL +A + +F +GA  A++AEL+ IA + +LV+ +
Sbjct: 137  EEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTV 196

Query: 800  DDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPES---------KRDILFLFDGSANL-V 849
             +F S   L ++L+     Y+ G  +   + +P +         KRDI+FL DGS+ L +
Sbjct: 197  PEFRSFGDLQEKLLP----YIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGL 252

Query: 850  GQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIK 909
              F  +RDF+ K+I  L +  +  ++AVAQY+D V+ E  F+ H +K E++  V++MK  
Sbjct: 253  ANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPL 312

Query: 910  TGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVV 969
             G AL  G ALD+ +  +F  SAG R  +G+ + LVL+  G+S D +  PA  LK+S ++
Sbjct: 313  DGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIM 372

Query: 970  PFIFQAKNADPAELEQIVL--SPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGE 1027
             F    K AD AELE+I    S  FI A      +  + P ++  L+++ +G P   S +
Sbjct: 373  AFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTL-SGTPEVHSNK 431

Query: 1028 KDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYM 1086
            +D++FLLDGS  V ++ FP +++FV  +V SLD+G D +RV +VQ+SD    EF LN+Y 
Sbjct: 432  RDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQ 491

Query: 1087 NKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGD 1146
             K D++  +RQL L GG   NTG+AL +V  N    + GSRI E VPQLL++LTA +S D
Sbjct: 492  TKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSED 551

Query: 1147 DVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVT 1206
                 +  + R G +   +G   A+  E++ I+F P     +  F  L  + Q + + +T
Sbjct: 552  SYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLT 611

Query: 1207 QLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGF 1266
                  +  + P+ QP        KRD++FL DGS +   +F  VR  + +++D L+V  
Sbjct: 612  TYVSGGVEEV-PLAQP------ESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKP 664

Query: 1267 DTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKR 1326
            + TR+AV Q+SDD KVE   + H SK E+ N V+R++ K G+ +N+G AL+Y  R IF +
Sbjct: 665  EGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVK 724

Query: 1327 PLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP 1385
              GSRIE+GV QFLVL+ +G+S D VD PA  LKQ GV PF   A+NAD  EL +I LSP
Sbjct: 725  SAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSP 784

Query: 1386 EYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSE 1445
             ++ +  +  ++  L              QI  LL S     PA  S   D+VFL+D SE
Sbjct: 785  AFILAAESLPKIGDLHP------------QIVNLLKSVHNGAPAPVSGEKDVVFLLDGSE 832

Query: 1446 GVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRR 1505
            GVR  GF  +++FV R+V  L++G  +VRV VVQ+S+   PEFYL +Y ++  V++A+R+
Sbjct: 833  GVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQ 891

Query: 1506 LRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRS 1565
            L L GG   NTG ALEFV RN+ V SAGSRI +GVPQ L+++   +S DDV   + V++ 
Sbjct: 892  LTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKR 951

Query: 1566 SGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIE----ERIMNSFGPSAATPA 1621
             G V +G+G  N D TE+QTI+  P     +  FR+L  ++    ER+        +   
Sbjct: 952  GGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQ 1011

Query: 1622 PPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLV 1681
            P  V  P PS     K D+VFL+DGS       FQ V   +  +VD +    D+ +V ++
Sbjct: 1012 P--VLQPLPSPGVGGKRDVVFLIDGS-QSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVI 1068

Query: 1682 QYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQ 1741
            Q++ DP  EF L   S+K ++ +A+ ++  KGGR  N    LE++  N F    GSR+++
Sbjct: 1069 QFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE 1128

Query: 1742 RVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGN 1801
             VPQ   +I+ GKS ++  D ++ L Q GV  F +  RN D EE+ KI+ +    F V  
Sbjct: 1129 GVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSPEYVFSVST 1187

Query: 1802 VQELSELSEQVL 1813
             +EL  L +++L
Sbjct: 1188 FRELPSLEQKLL 1199



 Score =  794 bits (2050), Expect = 0.0
 Identities = 473/1258 (37%), Positives = 734/1258 (58%), Gaps = 50/1258 (3%)

Query: 1    MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVRE 60
            MRKHRHLPLVAVFCLFLSGFPTTHAQQQQA      +ADIIFL+D S   G  +F ++ +
Sbjct: 1    MRKHRHLPLVAVFCLFLSGFPTTHAQQQQAAQD---SADIIFLIDGSNNTGSVNFAVILD 57

Query: 61   FLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGG-TNQTG 119
            FL ++++ L +G       +VQF+  P T F L+TY TK +VL  +  + + GG     G
Sbjct: 58   FLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIG 117

Query: 120  KGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVED 179
              L++++++H T+A GSR  +GVPQV+V+++ G S D +      LK A V  F +G + 
Sbjct: 118  LALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQA 177

Query: 180  ADEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETL-KDITAQ 238
            A    L+ IA++  +  +F +  F S  D+   L+  +             T+   +   
Sbjct: 178  ASRAELQHIATD--DNLVFTVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEV 235

Query: 239  DSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDT 298
            +  DI+FL+DGS+  G  NF  I DF+  ++++L IG   I+V V Q++D  R  F  +T
Sbjct: 236  NKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNT 295

Query: 299  YSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPS 358
            + TK +V+ AV+ +    G     G ALDFV  N FT + G R  EG+P++LVLI+ G S
Sbjct: 296  HPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKS 355

Query: 359  SDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPY 418
             DEI      LK++S+ +F +G + A +AEL+ IA D +LVF   EFR+   LQ  +LP 
Sbjct: 356  LDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRA-APLQ-GMLPG 413

Query: 419  IVGVAQRHIVLKPPTIVTQVIEV--NKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLE 476
            +         L P   ++   EV  NKRDI+FL+DGS+ +G  NF  +RDF+  ++  L+
Sbjct: 414  L---------LAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD 464

Query: 477  IGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNL 536
            IG D I+V + Q++DT   EF  NT+ TK +++  +R+++   GS L TGSAL +V  N 
Sbjct: 465  IGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANH 524

Query: 537  FTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIA 596
            FT + G R  E +P+LL+L+T G+S D   Q A  L R+ I+ F +G   A++AELE+IA
Sbjct: 525  FTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIA 584

Query: 597  FDSSLVFIPAEFRAAPLQGMLPGLLAPLRTL--SGTPEV----HSNKRDIIFLLDGSAN- 649
            F+ SLV++  +F + P   +   L+ PL T    G  EV      +KRDI+FL DGSAN 
Sbjct: 585  FNPSLVYLMDDFSSLP--ALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANL 642

Query: 650  VGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQL 709
            VG+  FP VRDF+  +++ L++  +  R+ + Q+SD    E   + +Q+K +IL  ++++
Sbjct: 643  VGQ--FPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRM 700

Query: 710  QLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRA 769
            +++ G  LN G AL Y     F ++ GSRI + V Q L+LL AG+S D     A+ L ++
Sbjct: 701  KIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQS 760

Query: 770  GILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPL 829
            G++ F   A  A+ AELEQI  +P+ +   +    +  L  Q++  L +  +G    V  
Sbjct: 761  GVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPV-- 818

Query: 830  AQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESR 889
                 ++D++FL DGS  +   FP++++F+ ++++ L+V  +  R+AV QYSD  + E  
Sbjct: 819  ---SGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFY 875

Query: 890  FDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVA 949
             + + +K +++N V+++ +  G   N G AL++  R I V SAGSRI +GV Q L++L A
Sbjct: 876  LNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTA 935

Query: 950  GRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQI 1009
             RS D V  P+  +K+ G VP      NAD  E++ I   P F +A  +  ++G +   I
Sbjct: 936  DRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVI 995

Query: 1010 -----------VNLLKSVHNGAPAP-VSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVES 1057
                       ++ L+ V    P+P V G++DVVFL+DGS+     F  ++  ++R+V+ 
Sbjct: 996  SERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDY 1055

Query: 1058 LDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLR 1117
            LDVG D  RVAV+Q+SD  + EF LN++ +K +V NAV++L   GG   N G ALE+V R
Sbjct: 1056 LDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSR 1115

Query: 1118 NILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQT 1177
            NI     GSRI EGVPQ L+++++ +S D+V +P+V +K+ G  P  I   NAD  E+  
Sbjct: 1116 NIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIA-RNADQEELVK 1174

Query: 1178 ISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVV 1235
            IS  P++  ++ TFR+L +++Q +   +T LT E++ +L    +  P PG  G  +V+
Sbjct: 1175 ISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTR-YPPPGEMGASEVL 1231



 Score =  550 bits (1418), Expect = e-156
 Identities = 345/1041 (33%), Positives = 558/1041 (53%), Gaps = 62/1041 (5%)

Query: 833  ESKRDILFLFDGSANLVG-QFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFD 891
            +   DI+FL DGS N     F V+ DFL  ++++L +  +  R+ V Q+SD+ +     D
Sbjct: 32   QDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLD 91

Query: 892  EHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGR 951
             + +K ++L  VK +    G+  N+G ALD+     F ++ GSR+E+GV Q LVL+ AG 
Sbjct: 92   TYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGP 151

Query: 952  SSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVN 1011
            SSD +      LKQ+ V  F   A+ A  AEL+ I      +         GDL  +++ 
Sbjct: 152  SSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLP 211

Query: 1012 LLKSVHNG-----APAPVS-----GEKDVVFLLDGSEGVR-SGFPLLKEFVQRVVESLDV 1060
             +  V         P  V+      ++D+VFL+DGS  +  + F  +++F+ +V++ L++
Sbjct: 212  YIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEI 271

Query: 1061 GQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNIL 1120
            GQD ++VAV QY+D  RPEFY N++  K++V+ AVR++  L G    TG+AL+FV  N+ 
Sbjct: 272  GQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLF 331

Query: 1121 VSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISF 1180
             SSAG R  EG+P+LL+++T  +S D++  P+  +KR   +   IG   AD  E++ I+F
Sbjct: 332  TSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAF 391

Query: 1181 IPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGV-GGKRDVVFLID 1239
                 V IP   +   +Q ++              L P+     +P V   KRD++FL+D
Sbjct: 392  DSSL-VFIPAEFRAAPLQGMLP-----------GLLAPLRTLSGTPEVHSNKRDIIFLLD 439

Query: 1240 GSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNA 1298
            GS + G   F YVR  +  LV+ LD+G D  RV ++QFSD P  EF LN + +K ++   
Sbjct: 440  GSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGH 499

Query: 1299 VQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVE 1358
            +++L+ +GG  +N G+AL YV  N F    GSRI E VPQ L+L+++G+S+D     A  
Sbjct: 500  LRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANA 559

Query: 1359 LKQFGVAPFTI-ARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQ 1417
            L + G+  F + A  A++ EL +I+ +P  V+ +  F  LP+L Q+L+ P+TT  S  ++
Sbjct: 560  LTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVE 619

Query: 1418 KLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGV 1477
            ++       P A      DI+FL D S  +    F  +RDF+ +I+  LN+ P   R+ V
Sbjct: 620  EV-------PLAQPESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAV 671

Query: 1478 VQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIE 1537
             Q+S+DV  E     ++S+  +L+ ++R++++ G  LN G AL++  R +FVKSAGSRIE
Sbjct: 672  AQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIE 731

Query: 1538 DGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVR 1597
            DGV Q LVL++ G+S D V   A  ++ SG+V      +N D  EL+ I   P  +    
Sbjct: 732  DGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAE 791

Query: 1598 EFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQE 1657
               ++ ++  +I+N    S    AP          P   + D+VFLLDGS   R   F  
Sbjct: 792  SLPKIGDLHPQIVNLL-KSVHNGAPA---------PVSGEKDVVFLLDGSEGVR-SGFPL 840

Query: 1658 VLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHA 1717
            +  FV  +V+++    D ++V +VQY+     EF+L  +  K+ +++A+ ++   GG   
Sbjct: 841  LKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTP 900

Query: 1718 NTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVG 1777
            NT   LE +  N  V  AGSR+ + VPQ+  V+T  +S +D ++ S+ + + G     +G
Sbjct: 901  NTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIG 960

Query: 1778 VRNIDSEEVGKI------ASNSATAFRVGNVQE-----LSELSEQVLETLHDAMHETLCP 1826
            + N D  E+  I      A    T  ++G VQ+     +++L+ + L  L   +     P
Sbjct: 961  IGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSP 1020

Query: 1827 GVTDAAKACNLDVILGFDGSR 1847
            GV         DV+   DGS+
Sbjct: 1021 GV-----GGKRDVVFLIDGSQ 1036



 Score =  378 bits (971), Expect = e-104
 Identities = 265/819 (32%), Positives = 412/819 (50%), Gaps = 43/819 (5%)

Query: 1233 DVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSS 1291
            D++FLIDGS + G   F  +   +  L++ L +G    RV V+QFSD+P+  F L+ +S+
Sbjct: 36   DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 95

Query: 1292 KDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDE 1351
            K +V  AV+ L   GG   N+G AL++V  N F R  GSR+EEGVPQ LVLIS+G S DE
Sbjct: 96   KAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDE 155

Query: 1352 VDDPAVELKQFGVAPFTI-ARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITT 1410
            +    V LKQ  V  F + A+ A + EL  I+     VF+V  FR    L++KLL  I  
Sbjct: 156  IRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIVG 215

Query: 1411 LTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGP 1470
            +    I  +L         +E +  DIVFL+D S  +    F  IRDF++++++RL IG 
Sbjct: 216  VAQRHI--VLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQ 273

Query: 1471 SKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVK 1530
              ++V V Q+++ V PEFY  T+ ++  V+ A+R+++   GS L TG AL+FV  NLF  
Sbjct: 274  DLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTS 333

Query: 1531 SAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDP 1590
            SAG R  +G+P+ LVL+ GGKS D++S+ AQ ++ S I++  +G++  D+ EL+ I  D 
Sbjct: 334  SAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDS 393

Query: 1591 RLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINF 1650
             LVF   EFR  P      +    P    P      TP        K DI+FLLDGS N 
Sbjct: 394  SLVFIPAEFRAAP------LQGMLPGLLAPLRTLSGTP---EVHSNKRDIIFLLDGSANV 444

Query: 1651 RRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVV 1710
             + +F  V  FV  +V+++    D+I+VGLVQ++  P  EF L  + TK  I+  + ++ 
Sbjct: 445  GKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQ 504

Query: 1711 YKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRG 1770
             +GG   NT   L ++  NHF    GSR+ + VPQ+  ++T G+S +     + ALT+ G
Sbjct: 505  LQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAG 564

Query: 1771 VKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLETLHDAMHETLCPGVTD 1830
            +  F VG    +  E+ +IA N +  + + +   L  L +Q+++ L   +   +   V  
Sbjct: 565  ILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGV-EEVPL 623

Query: 1831 AAKACNLDVILGFDGSRD-QNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSV 1889
            A      D++  FDGS +    F   + F  K+   LN       V   G      R++V
Sbjct: 624  AQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELN-------VKPEG-----TRIAV 671

Query: 1890 VANTPSGPVEA-FDFDEYQPEMLEKFRNMRSQH------PYVLTEDTLKVYLNKFRQSSP 1942
               +    VE+ FD  + +PE+L   + M+ +        Y L      +++        
Sbjct: 672  AQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIE 731

Query: 1943 DSV-KVVIHFTDGADGDLADLHRASENLRQEGVRALILVGLERVVNLERLMHLEFGRGFM 2001
            D V + ++    G   D  D    + NL+Q GV   I     +  +   L  +     F+
Sbjct: 732  DGVLQFLVLLVAGRSSDRVD--GPASNLKQSGVVPFIFQA--KNADPAELEQIVLSPAFI 787

Query: 2002 YDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQR 2040
                L    L    +L  Q+ N+ +    G P   SG++
Sbjct: 788  ----LAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEK 822



 Score =  229 bits (585), Expect = 3e-59
 Identities = 163/527 (30%), Positives = 259/527 (49%), Gaps = 38/527 (7%)

Query: 1433 DAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKT 1492
            D+ADI+FLID S       FA I DF+  ++ +L IG  ++RVGVVQFS++    F L T
Sbjct: 33   DSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDT 92

Query: 1493 YRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKS 1552
            Y ++A VL A++ L   GG   N G AL+FV  N F ++ GSR+E+GVPQ LVL+  G S
Sbjct: 93   YSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPS 152

Query: 1553 QDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNS 1612
             D++      ++ + + S G+G +   R ELQ I  D  LVFTV EFR   +++E+++  
Sbjct: 153  SDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLL-- 210

Query: 1613 FGPSAATPAPPGVDTPPPSRP----EKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDT 1668
              P     A   +   PP+      E  K DIVFL+DGS      +F  +  F+++++  
Sbjct: 211  --PYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQR 268

Query: 1669 VYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRV 1728
            +    D IQV + QY      EF+     TKR++I A+ K+    G    T   L+ +R 
Sbjct: 269  LEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRN 328

Query: 1729 NHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGK 1788
            N F   AG R  + +P++  +ITGGKS+++    +  L +  +  FA+G +  D  E+ +
Sbjct: 329  NLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEE 388

Query: 1789 IASNSA-----TAFRVGNVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGF 1843
            IA +S+       FR   +Q +       L TL            T    +   D+I   
Sbjct: 389  IAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSG----------TPEVHSNKRDIIFLL 438

Query: 1844 DGSRDQNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDF 1903
            DGS +    V +  F    D ++N ++ +         +  +RV +V  + + PV  F  
Sbjct: 439  DGSAN----VGKTNFPYVRDFVMNLVNSLDI------GNDNIRVGLVQFSDT-PVTEFSL 487

Query: 1904 DEYQ--PEMLEKFRNMRSQHPYVLTEDTL--KVYLNKFRQSSPDSVK 1946
            + YQ   ++L   R ++ Q    L   +    VY N F ++    ++
Sbjct: 488  NTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIR 534



 Score = 79.0 bits (193), Expect = 7e-14
 Identities = 95/406 (23%), Positives = 176/406 (43%), Gaps = 57/406 (14%)

Query: 2393 PLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNN 2452
            PL  P    ++ F  D S  +    F  +RD +  I+++L +     P G R+AV  Y++
Sbjct: 622  PLAQPESKRDILFLFDGSANL-VGQFPVVRDFLYKIIDELNVK----PEGTRIAVAQYSD 676

Query: 2453 EVTTEIRFADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTF-----KRVRNGFL 2507
            +V  E RF + + K  +L+ +K +++  T K  +L  A+ +  R  F      R+ +G L
Sbjct: 677  DVKVESRFDEHQSKPEILNLVKRMKIK-TGKALNLGYALDYAQRYIFVKSAGSRIEDGVL 735

Query: 2508 MRKVAVFFSNTPTRASPQLREAVLKLSDAGITP-LFLTRQEDRQLINALQINNTAVGHAL 2566
               V +       R+S ++      L  +G+ P +F  +  D   +  + ++   +  A 
Sbjct: 736  QFLVLL----VAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAE 791

Query: 2567 VLPAGRDLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDS 2626
             LP   DL   + N+L                      S  +   A    + D+ F+LD 
Sbjct: 792  SLPKIGDLHPQIVNLL---------------------KSVHNGAPAPVSGEKDVVFLLDG 830

Query: 2627 AETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVE 2686
            +E      F  +K+++  +V  LD+  D        RVAVVQ++             + E
Sbjct: 831  SEGVR-SGFPLLKEFVQRVVESLDVGQDR------VRVAVVQYSDR----------TRPE 873

Query: 2687 FSLTDYGSKEKLVDFLSRGMTQLQG-TRALGSAIEYTIENVFESAPNPRDLKIVVLMLTG 2745
            F L  Y +K+ +V+ + R +T L G T   G+A+E+ + N+  S+   R  + V  +L  
Sbjct: 874  FYLNSYMNKQDVVNAV-RQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIV 932

Query: 2746 EVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPN 2791
               ++  ++ +   +  K  G   + +GIG   +I E+ T +  P+
Sbjct: 933  LTADRSGDDVRNPSVVVKRGGAVPIGIGIG-NADITEMQTISFIPD 977



 Score = 58.9 bits (141), Expect = 8e-08
 Identities = 81/370 (21%), Positives = 155/370 (41%), Gaps = 52/370 (14%)

Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 2461
            ++ F +D S       F  + D +++++  L I         RV VV +++E  T     
Sbjct: 36   DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQI----RVGVVQFSDEPRTMFSLD 91

Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFL---MRKVAVFFSNT 2518
                K+ +L  +K L  A   +  ++  A+ FV  N F R     +   + +V V  S  
Sbjct: 92   TYSTKAQVLGAVKALGFA-GGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAG 150

Query: 2519 PTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALV--LPAGRDLTD 2576
            P+  S ++R  V+ L  A +    L      Q  +  ++ + A    LV  +P  R   D
Sbjct: 151  PS--SDEIRYGVVALKQASVFSFGL----GAQAASRAELQHIATDDNLVFTVPEFRSFGD 204

Query: 2577 FLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDI---DMAFILDSAETTTLF 2633
              E +L   V           G        +        +++   D+ F++D +    L 
Sbjct: 205  LQEKLLPYIV-----------GVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLA 253

Query: 2634 QFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYG 2693
             FN ++ +IA ++++L++  D        +VAV Q+A +          V+ EF    + 
Sbjct: 254  NFNAIRDFIAKVIQRLEIGQD------LIQVAVAQYADT----------VRPEFYFNTHP 297

Query: 2694 SKEKLVDFLSRGMTQLQGTRA-LGSAIEYTIENVFESAPNPRDL----KIVVLMLTGEVP 2748
            +K +++  + R M  L G+    GSA+++   N+F S+   R      K++VL+  G+  
Sbjct: 298  TKREVITAV-RKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSL 356

Query: 2749 EQQLEEAQRV 2758
            ++  + AQ +
Sbjct: 357  DEISQPAQEL 366



 Score = 55.5 bits (132), Expect = 8e-07
 Identities = 77/349 (22%), Positives = 145/349 (41%), Gaps = 42/349 (12%)

Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 2461
            ++ F LD S  V +  F  +RD V+++VN L I   N     RV +V +++   TE    
Sbjct: 433  DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDN----IRVGLVQFSDTPVTEFSLN 488

Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKV-AVFFSNTPT 2520
              + KS +L  ++ LQ+   S   +  +A+S+V  N F       +   V  +    T  
Sbjct: 489  TYQTKSDILGHLRQLQLQGGSGLNT-GSALSYVYANHFTEAGGSRIREHVPQLLLLLTAG 547

Query: 2521 RASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLEN 2580
            ++     +A   L+ AGI    LT        N  ++   A   +LV         +L +
Sbjct: 548  QSEDSYLQAANALTRAGI----LTFCVGASQANKAELEQIAFNPSLV---------YLMD 594

Query: 2581 VLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKK 2640
              +    L    I P   + S      +   A  +   D+ F+ D +    + QF  ++ 
Sbjct: 595  DFSSLPALPQQLIQPLTTYVS--GGVEEVPLAQPESKRDILFLFDGS-ANLVGQFPVVRD 651

Query: 2641 YIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVD 2700
            ++  ++ +L++ P+        R+AV Q++            VKVE    ++ SK ++++
Sbjct: 652  FLYKIIDELNVKPEG------TRIAVAQYSDD----------VKVESRFDEHQSKPEILN 695

Query: 2701 FLSRGMTQLQGTRALGSAIEYTIENVFESAPNPR----DLKIVVLMLTG 2745
             + R   +      LG A++Y    +F  +   R     L+ +VL++ G
Sbjct: 696  LVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAG 744



 Score = 43.1 bits (100), Expect = 0.004
 Identities = 93/421 (22%), Positives = 158/421 (37%), Gaps = 70/421 (16%)

Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 2461
            ++ F +D S  +    F  +RD +  ++  L I +       +VAV  Y + V  E  F 
Sbjct: 239  DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLI----QVAVAQYADTVRPEFYFN 294

Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFK-----RVRNGFLMRKVAVFFS 2516
                K  ++  ++ ++  L        +A+ FV  N F      R   G     V +   
Sbjct: 295  THPTKREVITAVRKMK-PLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLI--- 350

Query: 2517 NTPTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALV-LPA---GR 2572
             T  ++  ++ +   +L  + I    +  +   Q     ++   A   +LV +PA     
Sbjct: 351  -TGGKSLDEISQPAQELKRSSIMAFAIGNKGADQA----ELEEIAFDSSLVFIPAEFRAA 405

Query: 2573 DLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTL 2632
             L   L  +L     L            S  P     +        D+ F+LD +     
Sbjct: 406  PLQGMLPGLLAPLRTL------------SGTPEVHSNKR-------DIIFLLDGSANVGK 446

Query: 2633 FQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDY 2692
              F  ++ ++  LV  LD+  D        RV +VQ + +         PV  EFSL  Y
Sbjct: 447  TNFPYVRDFVMNLVNSLDIGNDN------IRVGLVQFSDT---------PV-TEFSLNTY 490

Query: 2693 GSKEKLVDFLSRGMTQLQGTRAL--GSAIEYTIENVFESAPNPR---DLKIVVLMLTGEV 2747
             +K  ++  L +   QLQG   L  GSA+ Y   N F  A   R    +  ++L+LT   
Sbjct: 491  QTKSDILGHLRQ--LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQ 548

Query: 2748 PEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKLVDKSTELNEE 2807
             E    +A   + +A   G     +G   + N  E+   A  P+ V+  L+D  + L   
Sbjct: 549  SEDSYLQAANALTRA---GILTFCVG-ASQANKAELEQIAFNPSLVY--LMDDFSSLPAL 602

Query: 2808 P 2808
            P
Sbjct: 603  P 603



 Score = 36.6 bits (83), Expect = 0.41
 Identities = 29/150 (19%), Positives = 69/150 (46%), Gaps = 7/150 (4%)

Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 2461
            ++ F +D S+    + F  +R ++  +V+ L +         RVAV+ ++++   E    
Sbjct: 1027 DVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDT----TRVAVIQFSDDPKVEFLLN 1081

Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPT- 2520
                K  + + ++ L+     +Q ++  A+ +V+RN FKR     +   V  F     + 
Sbjct: 1082 AHSSKDEVQNAVQRLRPK-GGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSG 1140

Query: 2521 RASPQLREAVLKLSDAGITPLFLTRQEDRQ 2550
            ++  ++ +  ++L   G+ P  + R  D++
Sbjct: 1141 KSDDEVDDPAVELKQFGVAPFTIARNADQE 1170


>gi|240255542 alpha 3 type VI collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1036

 Score = 1910 bits (4947), Expect = 0.0
 Identities = 993/1001 (99%), Positives = 997/1001 (99%), Gaps = 1/1001 (0%)

Query: 438  VIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEF 497
            VIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEF
Sbjct: 31   VIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEF 90

Query: 498  YFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLIT 557
            YFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLIT
Sbjct: 91   YFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLIT 150

Query: 558  GGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGML 617
            GGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGML
Sbjct: 151  GGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGML 210

Query: 618  PGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIR 677
            PGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIR
Sbjct: 211  PGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIR 270

Query: 678  VGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGS 737
            VGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGS
Sbjct: 271  VGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGS 330

Query: 738  RIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVY 797
            RIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVY
Sbjct: 331  RIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVY 390

Query: 798  LMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANLVGQFPVVRD 857
            LMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANLVGQFPVVRD
Sbjct: 391  LMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANLVGQFPVVRD 450

Query: 858  FLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLG 917
            FLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLG
Sbjct: 451  FLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLG 510

Query: 918  YALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKN 977
            YALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKN
Sbjct: 511  YALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKN 570

Query: 978  ADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGS 1037
            ADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGS
Sbjct: 571  ADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGS 630

Query: 1038 EGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQ 1097
            EGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQ
Sbjct: 631  EGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQ 690

Query: 1098 LTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKR 1157
            LTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKR
Sbjct: 691  LTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKR 750

Query: 1158 GGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQ 1217
            GGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQ
Sbjct: 751  GGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQ 810

Query: 1218 PVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFS 1277
            PVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFS
Sbjct: 811  PVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFS 870

Query: 1278 DDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVP 1337
            DDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVP
Sbjct: 871  DDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVP 930

Query: 1338 QFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVKISLSPEYVFSVSTFREL 1397
            QFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVKISLSPEYVFSVSTFREL
Sbjct: 931  QFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVKISLSPEYVFSVSTFREL 990

Query: 1398 PSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIV 1438
            PSLEQKLLTPITTLTSEQIQKLLASTRYPPP  E  A++++
Sbjct: 991  PSLEQKLLTPITTLTSEQIQKLLASTRYPPPG-EMGASEVL 1030



 Score =  699 bits (1805), Expect = 0.0
 Identities = 404/1024 (39%), Positives = 610/1024 (59%), Gaps = 40/1024 (3%)

Query: 1    MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVRE 60
            MRKHRHLPLVAVFCLFLSGFPTTHAQQQQA ++     DI+FLVD S  +G  +F  +R+
Sbjct: 1    MRKHRHLPLVAVFCLFLSGFPTTHAQQQQAVIEVNKR-DIVFLVDGSSALGLANFNAIRD 59

Query: 61   FLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTN-QTG 119
            F+  V++ L +G++    A+ Q+      EF  NT+ TK+EV++ +  M  + G+   TG
Sbjct: 60   FIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTG 119

Query: 120  KGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVED 179
              L+++  +  T +AG RA +G+P+++V++T G S D ++ P+ ELK + +  FAIG + 
Sbjct: 120  SALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKG 179

Query: 180  ADEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHS-SVSPERAGDTETLKDITAQ 238
            AD+  L+EIA +   + +        L  ++  L++ + + S +PE              
Sbjct: 180  ADQAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPE-----------VHS 228

Query: 239  DSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDT 298
            +  DIIFL+DGS N G  NF  + DF++NL+  L IG   IRVG+VQFSD P T FSL+T
Sbjct: 229  NKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNT 288

Query: 299  YSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPS 358
            Y TK+ +LG ++ L   GG   N G AL +V  NHFT AGGSR+ E VPQ+L+L++AG S
Sbjct: 289  YQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQS 348

Query: 359  SDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLL-- 416
             D       AL +A + +F +GA  A++AEL+ IA + +LV+ + +F S   L ++L+  
Sbjct: 349  EDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQP 408

Query: 417  --PYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQR 474
               Y+ G  +   + +P          +KRDI+FL DGS+ L +  F  +RDF+ K+I  
Sbjct: 409  LTTYVSGGVEEVPLAQPE---------SKRDILFLFDGSANL-VGQFPVVRDFLYKIIDE 458

Query: 475  LEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRN 534
            L +  +  ++AVAQY+D V+ E  F+ H +K E++  V++MK   G AL  G ALD+ + 
Sbjct: 459  LNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQR 518

Query: 535  NLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEE 594
             +F  SAG R  +G+ + LVL+  G+S D +  PA  LK+S ++ F    K AD AELE+
Sbjct: 519  YIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQ 578

Query: 595  IAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTL-SGTPEVHSNKRDIIFLLDGSANVGKT 653
            I    S  FI A      +  + P ++  L+++ +G P   S ++D++FLLDGS  V ++
Sbjct: 579  IVL--SPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGV-RS 635

Query: 654  NFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQG 713
             FP +++FV  +V SLD+G D +RV +VQ+SD    EF LN+Y  K D++  +RQL L G
Sbjct: 636  GFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLG 695

Query: 714  GSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILT 773
            G   NTG+AL +V  N    + GSRI E VPQLL++LTA +S D     +  + R G + 
Sbjct: 696  GPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVP 755

Query: 774  FCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEV-PLAQP 832
              +G   A+  E++ I+F P     +  F  L  + Q + + +T      +  + P+ QP
Sbjct: 756  IGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQP 815

Query: 833  ------ESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKV 886
                    KRD++FL DGS +   +F  VR  + +++D L+V  + TR+AV Q+SDD KV
Sbjct: 816  LPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKV 875

Query: 887  ESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVL 946
            E   + H SK E+ N V+R++ K G+ +N+G AL+Y  R IF +  GSRIE+GV QFLVL
Sbjct: 876  EFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVL 935

Query: 947  LVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLH 1006
            + +G+S D VD PA  LKQ GV PF   A+NAD  EL +I LSP ++ +  +  ++  L 
Sbjct: 936  ISSGKSDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSPEYVFSVSTFRELPSLE 994

Query: 1007 PQIV 1010
             +++
Sbjct: 995  QKLL 998



 Score =  641 bits (1653), Expect = 0.0
 Identities = 384/989 (38%), Positives = 572/989 (57%), Gaps = 34/989 (3%)

Query: 834  SKRDILFLFDGSANL-VGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDE 892
            +KRDI+FL DGS+ L +  F  +RDF+ K+I  L +  +  ++AVAQY+D V+ E  F+ 
Sbjct: 35   NKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNT 94

Query: 893  HQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRS 952
            H +K E++  V++MK   G AL  G ALD+ +  +F  SAG R  +G+ + LVL+  G+S
Sbjct: 95   HPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKS 154

Query: 953  SDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVL--SPAFILAAESLPKIGDLHPQIV 1010
             D +  PA  LK+S ++ F    K AD AELE+I    S  FI A      +  + P ++
Sbjct: 155  LDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLL 214

Query: 1011 NLLKSVHNGAPAPVSGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAV 1069
              L+++ +G P   S ++D++FLLDGS  V ++ FP +++FV  +V SLD+G D +RV +
Sbjct: 215  APLRTL-SGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGL 273

Query: 1070 VQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRIT 1129
            VQ+SD    EF LN+Y  K D++  +RQL L GG   NTG+AL +V  N    + GSRI 
Sbjct: 274  VQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIR 333

Query: 1130 EGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIP 1189
            E VPQLL++LTA +S D     +  + R G +   +G   A+  E++ I+F P     + 
Sbjct: 334  EHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMD 393

Query: 1190 TFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQ 1249
             F  L  + Q + + +T      +  + P+ QP        KRD++FL DGS +   +F 
Sbjct: 394  DFSSLPALPQQLIQPLTTYVSGGVEEV-PLAQP------ESKRDILFLFDGSANLVGQFP 446

Query: 1250 YVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQ 1309
             VR  + +++D L+V  + TR+AV Q+SDD KVE   + H SK E+ N V+R++ K G+ 
Sbjct: 447  VVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKA 506

Query: 1310 INVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI 1369
            +N+G AL+Y  R IF +  GSRIE+GV QFLVL+ +G+S D VD PA  LKQ GV PF  
Sbjct: 507  LNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIF 566

Query: 1370 -ARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPP 1428
             A+NAD  EL +I LSP ++ +  +  ++  L              QI  LL S     P
Sbjct: 567  QAKNADPAELEQIVLSPAFILAAESLPKIGDLHP------------QIVNLLKSVHNGAP 614

Query: 1429 AVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEF 1488
            A  S   D+VFL+D SEGVR  GF  +++FV R+V  L++G  +VRV VVQ+S+   PEF
Sbjct: 615  APVSGEKDVVFLLDGSEGVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEF 673

Query: 1489 YLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVL 1548
            YL +Y ++  V++A+R+L L GG   NTG ALEFV RN+ V SAGSRI +GVPQ L+++ 
Sbjct: 674  YLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLT 733

Query: 1549 GGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIE-- 1606
              +S DDV   + V++  G V +G+G  N D TE+QTI+  P     +  FR+L  ++  
Sbjct: 734  ADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQV 793

Query: 1607 --ERIMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSE 1664
              ER+        +   P  V  P PS     K D+VFL+DGS       FQ V   +  
Sbjct: 794  ISERVTQLTREELSRLQP--VLQPLPSPGVGGKRDVVFLIDGS-QSAGPEFQYVRTLIER 850

Query: 1665 IVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLE 1724
            +VD +    D+ +V ++Q++ DP  EF L   S+K ++ +A+ ++  KGGR  N    LE
Sbjct: 851  LVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALE 910

Query: 1725 HLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSE 1784
            ++  N F    GSR+++ VPQ   +I+ GKS ++  D ++ L Q GV  F +  RN D E
Sbjct: 911  YVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI-ARNADQE 969

Query: 1785 EVGKIASNSATAFRVGNVQELSELSEQVL 1813
            E+ KI+ +    F V   +EL  L +++L
Sbjct: 970  ELVKISLSPEYVFSVSTFRELPSLEQKLL 998



 Score =  458 bits (1178), Expect = e-128
 Identities = 282/836 (33%), Positives = 459/836 (54%), Gaps = 51/836 (6%)

Query: 1027 EKDVVFLLDGSEGVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSY 1085
            ++D+VFL+DGS  +  + F  +++F+ +V++ L++GQD ++VAV QY+D  RPEFY N++
Sbjct: 36   KRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTH 95

Query: 1086 MNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSG 1145
              K++V+ AVR++  L G    TG+AL+FV  N+  SSAG R  EG+P+LL+++T  +S 
Sbjct: 96   PTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSL 155

Query: 1146 DDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERV 1205
            D++  P+  +KR   +   IG   AD  E++ I+F     V IP   +   +Q ++    
Sbjct: 156  DEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSL-VFIPAEFRAAPLQGMLP--- 211

Query: 1206 TQLTREELSRLQPVLQPLPSPGV-GGKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLD 1263
                      L P+     +P V   KRD++FL+DGS + G   F YVR  +  LV+ LD
Sbjct: 212  --------GLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD 263

Query: 1264 VGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNI 1323
            +G D  RV ++QFSD P  EF LN + +K ++   +++L+ +GG  +N G+AL YV  N 
Sbjct: 264  IGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANH 323

Query: 1324 FKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKIS 1382
            F    GSRI E VPQ L+L+++G+S+D     A  L + G+  F + A  A++ EL +I+
Sbjct: 324  FTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIA 383

Query: 1383 LSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLID 1442
             +P  V+ +  F  LP+L Q+L+ P+TT  S  ++++       P A      DI+FL D
Sbjct: 384  FNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEV-------PLAQPESKRDILFLFD 436

Query: 1443 SSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDA 1502
             S  +    F  +RDF+ +I+  LN+ P   R+ V Q+S+DV  E     ++S+  +L+ 
Sbjct: 437  GSANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNL 495

Query: 1503 IRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQV 1562
            ++R++++ G  LN G AL++  R +FVKSAGSRIEDGV Q LVL++ G+S D V   A  
Sbjct: 496  VKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASN 555

Query: 1563 IRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAP 1622
            ++ SG+V      +N D  EL+ I   P  +       ++ ++  +I+N    S    AP
Sbjct: 556  LKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLL-KSVHNGAP 614

Query: 1623 PGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQ 1682
                      P   + D+VFLLDGS   R   F  +  FV  +V+++    D ++V +VQ
Sbjct: 615  A---------PVSGEKDVVFLLDGSEGVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQ 664

Query: 1683 YNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQR 1742
            Y+     EF+L  +  K+ +++A+ ++   GG   NT   LE +  N  V  AGSR+ + 
Sbjct: 665  YSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEG 724

Query: 1743 VPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKI------ASNSATA 1796
            VPQ+  V+T  +S +D ++ S+ + + G     +G+ N D  E+  I      A    T 
Sbjct: 725  VPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTF 784

Query: 1797 FRVGNVQE-----LSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGSR 1847
             ++G VQ+     +++L+ + L  L   +     PGV         DV+   DGS+
Sbjct: 785  RQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGV-----GGKRDVVFLIDGSQ 835



 Score =  258 bits (660), Expect = 5e-68
 Identities = 186/620 (30%), Positives = 302/620 (48%), Gaps = 39/620 (6%)

Query: 1430 VESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFY 1489
            +E +  DIVFL+D S  +    F  IRDF++++++RL IG   ++V V Q+++ V PEFY
Sbjct: 32   IEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFY 91

Query: 1490 LKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLG 1549
              T+ ++  V+ A+R+++   GS L TG AL+FV  NLF  SAG R  +G+P+ LVL+ G
Sbjct: 92   FNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITG 151

Query: 1550 GKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERI 1609
            GKS D++S+ AQ ++ S I++  +G++  D+ EL+ I  D  LVF   EFR  P      
Sbjct: 152  GKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAP------ 205

Query: 1610 MNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTV 1669
            +    P    P      TP        K DI+FLLDGS N  + +F  V  FV  +V+++
Sbjct: 206  LQGMLPGLLAPLRTLSGTP---EVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSL 262

Query: 1670 YEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVN 1729
                D+I+VGLVQ++  P  EF L  + TK  I+  + ++  +GG   NT   L ++  N
Sbjct: 263  DIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYAN 322

Query: 1730 HFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKI 1789
            HF    GSR+ + VPQ+  ++T G+S +     + ALT+ G+  F VG    +  E+ +I
Sbjct: 323  HFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQI 382

Query: 1790 ASNSATAFRVGNVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGSRD- 1848
            A N +  + + +   L  L +Q+++ L   +   +   V  A      D++  FDGS + 
Sbjct: 383  AFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGV-EEVPLAQPESKRDILFLFDGSANL 441

Query: 1849 QNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEA-FDFDEYQ 1907
               F   + F  K+   LN       V   G      R++V   +    VE+ FD  + +
Sbjct: 442  VGQFPVVRDFLYKIIDELN-------VKPEG-----TRIAVAQYSDDVKVESRFDEHQSK 489

Query: 1908 PEMLEKFRNMRSQH------PYVLTEDTLKVYLNKFRQSSPDSV-KVVIHFTDGADGDLA 1960
            PE+L   + M+ +        Y L      +++        D V + ++    G   D  
Sbjct: 490  PEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRV 549

Query: 1961 DLHRASENLRQEGVRALILVGLERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQ 2020
            D    + NL+Q GV   I     +  +   L  +     F+    L    L    +L  Q
Sbjct: 550  D--GPASNLKQSGVVPFIFQA--KNADPAELEQIVLSPAFI----LAAESLPKIGDLHPQ 601

Query: 2021 LDNIAEKACCGVPCKCSGQR 2040
            + N+ +    G P   SG++
Sbjct: 602  IVNLLKSVHNGAPAPVSGEK 621



 Score =  217 bits (553), Expect = 1e-55
 Identities = 141/404 (34%), Positives = 218/404 (53%), Gaps = 11/404 (2%)

Query: 32   VKNGAAA------DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNG 85
            V NGA A      D++FL+D S  +    F L++EF+  VV+SL VG++    A+VQ++ 
Sbjct: 609  VHNGAPAPVSGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSD 667

Query: 86   NPHTEFLLNTYRTKQEVLSHISNMSYIGG-TNQTGKGLEYIMQSHLTKAAGSRAGDGVPQ 144
                EF LN+Y  KQ+V++ +  ++ +GG T  TG  LE+++++ L  +AGSR  +GVPQ
Sbjct: 668  RTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQ 727

Query: 145  VIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEP-LNMHMFNLENF 203
            +++VLT   S D +  PS  +K        IG+ +AD   ++ I+  P   + +      
Sbjct: 728  LLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQL 787

Query: 204  TSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAVILD 263
             ++  ++   V+ +            + L         D++FLIDGS + G   F  +  
Sbjct: 788  GTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGP-EFQYVRT 846

Query: 264  FLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIG 323
             +  L++ L +G    RV V+QFSD+P+  F L+ +S+K +V  AV+ L   GG   N+G
Sbjct: 847  LIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVG 906

Query: 324  LALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQA 383
             AL++V  N F R  GSR+EEGVPQ LVLIS+G S DE+    V LKQ  V  F + A+ 
Sbjct: 907  NALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI-ARN 965

Query: 384  ASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIVGVAQRHI 427
            A + EL  I+     VF+V  FR    L++KLL  I  +    I
Sbjct: 966  ADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQI 1009



 Score = 79.0 bits (193), Expect = 7e-14
 Identities = 95/406 (23%), Positives = 176/406 (43%), Gaps = 57/406 (14%)

Query: 2393 PLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNN 2452
            PL  P    ++ F  D S  +    F  +RD +  I+++L +     P G R+AV  Y++
Sbjct: 421  PLAQPESKRDILFLFDGSANL-VGQFPVVRDFLYKIIDELNVK----PEGTRIAVAQYSD 475

Query: 2453 EVTTEIRFADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTF-----KRVRNGFL 2507
            +V  E RF + + K  +L+ +K +++  T K  +L  A+ +  R  F      R+ +G L
Sbjct: 476  DVKVESRFDEHQSKPEILNLVKRMKIK-TGKALNLGYALDYAQRYIFVKSAGSRIEDGVL 534

Query: 2508 MRKVAVFFSNTPTRASPQLREAVLKLSDAGITP-LFLTRQEDRQLINALQINNTAVGHAL 2566
               V +       R+S ++      L  +G+ P +F  +  D   +  + ++   +  A 
Sbjct: 535  QFLVLL----VAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAE 590

Query: 2567 VLPAGRDLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDS 2626
             LP   DL   + N+L                      S  +   A    + D+ F+LD 
Sbjct: 591  SLPKIGDLHPQIVNLL---------------------KSVHNGAPAPVSGEKDVVFLLDG 629

Query: 2627 AETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVE 2686
            +E      F  +K+++  +V  LD+  D        RVAVVQ++             + E
Sbjct: 630  SEGVR-SGFPLLKEFVQRVVESLDVGQDR------VRVAVVQYSDR----------TRPE 672

Query: 2687 FSLTDYGSKEKLVDFLSRGMTQLQG-TRALGSAIEYTIENVFESAPNPRDLKIVVLMLTG 2745
            F L  Y +K+ +V+ + R +T L G T   G+A+E+ + N+  S+   R  + V  +L  
Sbjct: 673  FYLNSYMNKQDVVNAV-RQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIV 731

Query: 2746 EVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPN 2791
               ++  ++ +   +  K  G   + +GIG   +I E+ T +  P+
Sbjct: 732  LTADRSGDDVRNPSVVVKRGGAVPIGIGIG-NADITEMQTISFIPD 776



 Score = 55.5 bits (132), Expect = 8e-07
 Identities = 77/349 (22%), Positives = 145/349 (41%), Gaps = 42/349 (12%)

Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 2461
            ++ F LD S  V +  F  +RD V+++VN L I   N     RV +V +++   TE    
Sbjct: 232  DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDN----IRVGLVQFSDTPVTEFSLN 287

Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKV-AVFFSNTPT 2520
              + KS +L  ++ LQ+   S   +  +A+S+V  N F       +   V  +    T  
Sbjct: 288  TYQTKSDILGHLRQLQLQGGSGLNT-GSALSYVYANHFTEAGGSRIREHVPQLLLLLTAG 346

Query: 2521 RASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLEN 2580
            ++     +A   L+ AGI    LT        N  ++   A   +LV         +L +
Sbjct: 347  QSEDSYLQAANALTRAGI----LTFCVGASQANKAELEQIAFNPSLV---------YLMD 393

Query: 2581 VLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKK 2640
              +    L    I P   + S      +   A  +   D+ F+ D +    + QF  ++ 
Sbjct: 394  DFSSLPALPQQLIQPLTTYVS--GGVEEVPLAQPESKRDILFLFDGS-ANLVGQFPVVRD 450

Query: 2641 YIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVD 2700
            ++  ++ +L++ P+        R+AV Q++            VKVE    ++ SK ++++
Sbjct: 451  FLYKIIDELNVKPEG------TRIAVAQYSDD----------VKVESRFDEHQSKPEILN 494

Query: 2701 FLSRGMTQLQGTRALGSAIEYTIENVFESAPNPR----DLKIVVLMLTG 2745
             + R   +      LG A++Y    +F  +   R     L+ +VL++ G
Sbjct: 495  LVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAG 543



 Score = 43.9 bits (102), Expect = 0.003
 Identities = 36/145 (24%), Positives = 73/145 (50%), Gaps = 22/145 (15%)

Query: 2619 DMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNA 2678
            D+ F++D +    L  FN ++ +IA ++++L++  D        +VAV Q+A +      
Sbjct: 38   DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQD------LIQVAVAQYADT------ 85

Query: 2679 SMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRA-LGSAIEYTIENVFESAPNPRDL- 2736
                V+ EF    + +K +++  + R M  L G+    GSA+++   N+F S+   R   
Sbjct: 86   ----VRPEFYFNTHPTKREVITAV-RKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAE 140

Query: 2737 ---KIVVLMLTGEVPEQQLEEAQRV 2758
               K++VL+  G+  ++  + AQ +
Sbjct: 141  GIPKLLVLITGGKSLDEISQPAQEL 165



 Score = 43.1 bits (100), Expect = 0.004
 Identities = 93/421 (22%), Positives = 158/421 (37%), Gaps = 70/421 (16%)

Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 2461
            ++ F +D S  +    F  +RD +  ++  L I +       +VAV  Y + V  E  F 
Sbjct: 38   DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLI----QVAVAQYADTVRPEFYFN 93

Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFK-----RVRNGFLMRKVAVFFS 2516
                K  ++  ++ ++  L        +A+ FV  N F      R   G     V +   
Sbjct: 94   THPTKREVITAVRKMK-PLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLI--- 149

Query: 2517 NTPTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALV-LPA---GR 2572
             T  ++  ++ +   +L  + I    +  +   Q     ++   A   +LV +PA     
Sbjct: 150  -TGGKSLDEISQPAQELKRSSIMAFAIGNKGADQA----ELEEIAFDSSLVFIPAEFRAA 204

Query: 2573 DLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTL 2632
             L   L  +L     L            S  P     +        D+ F+LD +     
Sbjct: 205  PLQGMLPGLLAPLRTL------------SGTPEVHSNKR-------DIIFLLDGSANVGK 245

Query: 2633 FQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDY 2692
              F  ++ ++  LV  LD+  D        RV +VQ + +         PV  EFSL  Y
Sbjct: 246  TNFPYVRDFVMNLVNSLDIGNDN------IRVGLVQFSDT---------PV-TEFSLNTY 289

Query: 2693 GSKEKLVDFLSRGMTQLQGTRAL--GSAIEYTIENVFESAPNPR---DLKIVVLMLTGEV 2747
             +K  ++  L +   QLQG   L  GSA+ Y   N F  A   R    +  ++L+LT   
Sbjct: 290  QTKSDILGHLRQ--LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQ 347

Query: 2748 PEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKLVDKSTELNEE 2807
             E    +A   + +A   G     +G   + N  E+   A  P+ V+  L+D  + L   
Sbjct: 348  SEDSYLQAANALTRA---GILTFCVG-ASQANKAELEQIAFNPSLVY--LMDDFSSLPAL 401

Query: 2808 P 2808
            P
Sbjct: 402  P 402



 Score = 36.6 bits (83), Expect = 0.41
 Identities = 29/150 (19%), Positives = 69/150 (46%), Gaps = 7/150 (4%)

Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 2461
            ++ F +D S+    + F  +R ++  +V+ L +         RVAV+ ++++   E    
Sbjct: 826  DVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDT----TRVAVIQFSDDPKVEFLLN 880

Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPT- 2520
                K  + + ++ L+     +Q ++  A+ +V+RN FKR     +   V  F     + 
Sbjct: 881  AHSSKDEVQNAVQRLRPK-GGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSG 939

Query: 2521 RASPQLREAVLKLSDAGITPLFLTRQEDRQ 2550
            ++  ++ +  ++L   G+ P  + R  D++
Sbjct: 940  KSDDEVDDPAVELKQFGVAPFTIARNADQE 969


>gi|156616290 collagen type VI alpha 6 [Homo sapiens]
          Length = 2263

 Score = 1144 bits (2960), Expect = 0.0
 Identities = 730/2191 (33%), Positives = 1148/2191 (52%), Gaps = 116/2191 (5%)

Query: 639  DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQT 698
            D++FL+D S  +G  +FP+V+ F+  +++SL I  D  RV L Q+SD   +EF L+T++ 
Sbjct: 27   DVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFKG 86

Query: 699  KSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDS 758
            +S +L HLR+     G  L  G AL   +  +F+     R ++  P +L++L + +SED+
Sbjct: 87   RSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVLASSESEDN 146

Query: 759  YLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYL--MDDFSSLPALPQQLIQPL 816
              +A+ AL + G+    VG  +A++  L+ +A +     L  + D S        +I+ +
Sbjct: 147  VEEASKALRKDGVKIISVGVQKASEENLKAMATSQFHFNLRTVRDLSMFSQNMTHIIKDV 206

Query: 817  TTYVSGGVEE--VPLAQPESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGT 873
              Y  G V++  V   Q  S  D++FL D S N   + F  ++ FL + +  L++K    
Sbjct: 207  IKYKEGAVDDIFVEACQGPSMADVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCM 266

Query: 874  RIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAG 933
            R+ +  YS++ KV +      +K E+L  ++ +  +TGKA   G A+   ++ +F    G
Sbjct: 267  RVGLVAYSNETKVINSLSMGINKSEVLQHIQNLSPRTGKAYT-GAAIKKLRKEVFSARNG 325

Query: 934  SRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFI 993
            SR   GV Q  VL+    S D V   A NL++ GV  F    + A   +LE+I   PA  
Sbjct: 326  SRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAEQ 385

Query: 994  LAAESLPKIGDLHPQIVNLLKSVHNGAPAPVS----------------GEKDVVFLLDGS 1037
              ++ L    DL       LK + N     VS                 E D+  L+DGS
Sbjct: 386  YVSK-LKTFADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSGCVDTEEADIYLLIDGS 444

Query: 1038 EGVRS-GFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVR 1096
               ++  F  +K F+  VV   ++   +VRV  VQY+D    EF +N Y NKQD+  A+ 
Sbjct: 445  GSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEINKYSNKQDLGKAIE 504

Query: 1097 QLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVK 1156
             +  +GG T NTGAAL F L   L+  A  +    VP  L+VLT   S D +  P+  ++
Sbjct: 505  NIRQMGGNT-NTGAALNFTLS--LLQKAKKQRGNKVPCHLVVLTNGMSKDSILEPANRLR 561

Query: 1157 RGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQ-QVISERVTQLTREELSR 1215
                    IGI  A+ T+++ I+        +  F  L  ++ QV+ E  T+   +E+  
Sbjct: 562  EEHIRVYAIGIKEANQTQLREIAGEEKRVYYVHDFDALKDIRNQVVQEICTEEACKEM-- 619

Query: 1216 LQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVI 1274
                           K D++FL+D S S GPE F  ++T ++ LV    +G D  ++ V+
Sbjct: 620  ---------------KADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVV 664

Query: 1275 QFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE 1334
            QFSD  K EF LN   S+ ++ NA+ ++   G   +  G+AL +VS+  F    G+R   
Sbjct: 665  QFSDINKEEFQLNRFMSQSDISNAIDQMAHIGQTTLT-GSALSFVSQ-YFSPTKGAR--P 720

Query: 1335 GVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIAR-NADQEELVKISLSPEYVFSVST 1393
             + +FL+LI+ G++ D V +PAV L+Q GV  +++    ++  +L +IS  PE VF V  
Sbjct: 721  NIRKFLILITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVEN 780

Query: 1394 FRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFA 1453
            F  L  +E  L+  I +   E+ +++             +  D+VF+IDSS  +  D + 
Sbjct: 781  FDILQRIEDDLVFGICS-PREECKRI-------------EVLDVVFVIDSSGSIDYDEYN 826

Query: 1454 HIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSP 1513
             ++DF+  +V++ ++G ++VR G +++++D    FYL  + ++  V+  ++  +  GGS 
Sbjct: 827  IMKDFMIGLVKKADVGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGST 886

Query: 1514 LNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQD--DVSRFAQVIRSSGIVSL 1571
              T +AL F + ++F ++ GSR+  GVPQ L+++  G+S D   ++  A+ +R  GI+ L
Sbjct: 887  Y-TAEALGF-SDHMFTEARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVL 944

Query: 1572 GVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPS 1631
             VG    +  EL  +       F V  F  L  I   +  S   S+              
Sbjct: 945  AVGIDGANPVELLAMAGSSDKYFFVETFGGLKGIFSDVTASVCNSSKVDC---------- 994

Query: 1632 RPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEF 1691
              E  K D+VFL+DGS + + + F+++  F++ +V       + +++G  Q++     EF
Sbjct: 995  --EIDKVDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEF 1052

Query: 1692 FLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNH-FVPEAGSRLDQRVPQIAFVI 1750
             L  F  +++I   I  +    G   NT +G     V H F P+ GSR++   PQ+  V+
Sbjct: 1053 PLGTFIGEKEISFQIENIKQIFG---NTHIGAALREVEHYFRPDMGSRINTGTPQVLLVL 1109

Query: 1751 TGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSE 1810
            T G+S ++    + AL  RG+ +++VG+ ++D +++ +I   +     V N  EL ++++
Sbjct: 1110 TDGQSQDEVAQAAEALRHRGIDIYSVGIGDVDDQQLIQITGTAEKKLTVHNFDELKKVNK 1169

Query: 1811 QVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGS---RDQNVFVAQKGFESKVDAILN 1867
            +++  +        C   T     C +DV++GFD S   + Q +   Q   E+ +  IL 
Sbjct: 1170 RIVRNI--------C--TTAGESNCFVDVVVGFDVSTQEKGQTLLEGQPWMETYLQDILR 1219

Query: 1868 RISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFD--FDEYQPEMLEKFRNMRSQHPYVL 1925
             IS ++ VSC  G    V V+      +  +E +   F+ Y   +L   +++  + P +L
Sbjct: 1220 AISSLNGVSCEVGTETQVSVAFQV---TNAMEKYSPKFEIYSENILNSLKDITVKGPSLL 1276

Query: 1926 TEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILVGLERV 1985
              + L    + F+  S    KVV+ F+DG D D+  L + S+ LR+EG+ ALI V L+  
Sbjct: 1277 NANLLDSLWDTFQNKSAARGKVVLLFSDGLDDDVEKLEQKSDELRKEGLNALITVALDGP 1336

Query: 1986 VN---LERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQRGD 2042
             +   L  L ++EFG+GF Y   L + + +L   L++QL N+AE+ CC + CKC G  G 
Sbjct: 1337 ADSSDLADLPYIEFGKGFEYRTQLSIGMRELGSRLSKQLVNVAERTCCCLFCKCIGGDGT 1396

Query: 2043 RGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGE 2102
             G  G  G +G PG  G  GY G+EG  GERG PG  G QG +GC G +G KG+RG  G+
Sbjct: 1397 MGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNRGLNGQ 1456

Query: 2103 KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQ 2162
            +GEVGE G+DGL+GE GD GLPG  GEKG+ G +G  G RG  G+RG  G+RGDPG PG 
Sbjct: 1457 EGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDPGAPGV 1516

Query: 2163 DSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEG 2222
            DS   GP G  G+ G  G  G  G PG PG   K    GRRG  G +G  G PG  G EG
Sbjct: 1517 DSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEG 1576

Query: 2223 EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKG 2282
              G +G QGP G AG  G  G  G  GP+G  G  G  G +GR G  G KGEPG+ G KG
Sbjct: 1577 SLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKG 1636

Query: 2283 GIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGR 2342
             +G  GPRG  G+DG  G GS GR+G KG+ GFPG  GPKG  G+PG  G TG KG RG+
Sbjct: 1637 AVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGK 1696

Query: 2343 RGNSGPPGIVGQKGDPGYPGPAGPKGNRG-DSIDQCALIQSIKDKCPCCYGPLECPVFPT 2401
              ++G PG +G  G+PG PG  G KG +G  S   C LIQ ++D+ P  +G  ECPV PT
Sbjct: 1697 MISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKPECPVHPT 1756

Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 2461
            EL FALD S  V +  F RM++++  +V D+ + E++CP GA +A+++YN+     +RF+
Sbjct: 1757 ELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYNSHARHLVRFS 1816

Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTR 2521
            D+ +KS LL +I+ +    +S  + +  AM F++RN FKR   G   RK+A FFS+  + 
Sbjct: 1817 DAYKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKRTLPGAHTRKIATFFSSGQSA 1876

Query: 2522 ASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLENV 2581
             +  +  A ++     I P+ +T      +  A  I++T     +V+P+G D    LE +
Sbjct: 1877 DAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAIDDTGTFQVIVVPSGADYIPALERL 1936

Query: 2582 LTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKY 2641
              C  C D+C  D SC            R       +D AF+LD++      +F +++ +
Sbjct: 1937 QRCTFCYDVCKPDASCD---------QARPPPVQSYMDAAFLLDASRNMGSAEFEDIRAF 1987

Query: 2642 IAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDF 2701
            +  L+   +++P+P+ S    RVA++ HAP + + N    PV+ EF+LT Y SK  +   
Sbjct: 1988 LGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEFNLTTYRSKRLMKRH 2047

Query: 2702 LSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQ 2761
            +   + QL G   +G A+++T++NVF S PN R  K++ ++  GE      E  ++  L+
Sbjct: 2048 VHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRNKVIFVISAGETSHLDGEILKKESLR 2107

Query: 2762 AKCKGYFFVVLGIGRKVNIKEVYTFASEPND 2792
            AKC+GY   V  +G   + KE+   AS P D
Sbjct: 2108 AKCQGYALFVFSLGPIWDDKELEDLASHPLD 2138



 Score =  478 bits (1230), Expect = e-134
 Identities = 338/1185 (28%), Positives = 613/1185 (51%), Gaps = 52/1185 (4%)

Query: 38   ADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYR 97
            AD++FLVDSS  +G + F  V+ F+  ++ SL +  + +  AL Q++   H+EF L+T++
Sbjct: 26   ADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFK 85

Query: 98   TKQEVLSHI-SNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKD 156
             +  +L+H+  N  +IGG+ Q GK L+   +++ +  A  R     P ++VVL    S+D
Sbjct: 86   GRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVLASSESED 145

Query: 157  GLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSC 216
             +   S  L+   V + ++GV+ A E  LK +A+   +   FNL     L     N+   
Sbjct: 146  NVEEASKALRKDGVKIISVGVQKASEENLKAMATSQFH---FNLRTVRDLSMFSQNMTHI 202

Query: 217  VHSSVS-PERAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIG 275
            +   +   E A D   ++       AD++FL+D S N    NF  +  FL   +  L I 
Sbjct: 203  IKDVIKYKEGAVDDIFVEACQGPSMADVVFLLDMSINGSEENFDYLKGFLEESVSALDIK 262

Query: 276  TQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFT 335
               +RVG+V +S+E + + SL     K++VL  ++ L    G+ A  G A+  + +  F+
Sbjct: 263  ENCMRVGLVAYSNETKVINSLSMGINKSEVLQHIQNLSPRTGK-AYTGAAIKKLRKEVFS 321

Query: 336  RAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATD 395
               GSR  +GVPQ+ VL++   S D +    V L++  V  F LG + AS  +L+ IA+ 
Sbjct: 322  ARNGSRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASH 381

Query: 396  DNLVFTVPEFRSFGDLQEKLLPYIVGVAQR--HIVL----KPPTIVTQVIEVNKRDIVFL 449
                + V + ++F DL      ++  +  +  H V     +  T+ +  ++  + DI  L
Sbjct: 382  PAEQY-VSKLKTFADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSGCVDTEEADIYLL 440

Query: 450  VDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVI 509
            +DGS +    +F+ ++ F+++V+    I    ++V   QYAD+   EF  N +  K+++ 
Sbjct: 441  IDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEINKYSNKQDLG 500

Query: 510  TAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPA 569
             A+  ++ + G+   TG+AL+F  + L    A  +    +P  LV++T G S D I +PA
Sbjct: 501  KAIENIRQMGGNT-NTGAALNFTLSLL--QKAKKQRGNKVPCHLVVLTNGMSKDSILEPA 557

Query: 570  QELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSG 629
              L+   I  +AIG K A+Q +L EIA +   V+   +F A  L+ +   ++  + T   
Sbjct: 558  NRLREEHIRVYAIGIKEANQTQLREIAGEEKRVYYVHDFDA--LKDIRNQVVQEICTEEA 615

Query: 630  TPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVT 689
              E+   K DI+FL+D S ++G  NF  ++ F+ NLV+   IG D +++G+VQFSD    
Sbjct: 616  CKEM---KADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINKE 672

Query: 690  EFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLL 749
            EF LN + ++SDI   + Q+   G + L TGSALS+V + +F+   G+  R ++ + L+L
Sbjct: 673  EFQLNRFMSQSDISNAIDQMAHIGQTTL-TGSALSFV-SQYFSPTKGA--RPNIRKFLIL 728

Query: 750  LTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALP 809
            +T G+++D   + A  L + G++ + VG   +N  +LE+I+  P +V+ +++F  L  + 
Sbjct: 729  ITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVENFDILQRIE 788

Query: 810  QQLIQPLTTYVSGGVEEVPLAQPESKR----DILFLFDGSANL-VGQFPVVRDFLYKIID 864
              L+  + +            + E KR    D++F+ D S ++   ++ +++DF+  ++ 
Sbjct: 789  DDLVFGICS-----------PREECKRIEVLDVVFVIDSSGSIDYDEYNIMKDFMIGLVK 837

Query: 865  ELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQ 924
            + +V     R    +Y+DD +V    D+  +K E++++++  +   G       AL ++ 
Sbjct: 838  KADVGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGSTYT-AEALGFSD 896

Query: 925  RYIFVKSAGSRIEDGVLQFLVLLVAGRS--SDRVDGPASNLKQSGVVPFIFQAKNADPAE 982
             ++F ++ GSR+  GV Q L+++  G S  +D+++  A  L+  G++        A+P E
Sbjct: 897  -HMFTEARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVE 955

Query: 983  LEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEK-DVVFLLDGSEGVR 1041
            L  +  S       E+    G L     ++  SV N +      +K D+VFL+DGS  ++
Sbjct: 956  LLAMAGSSDKYFFVET---FGGLKGIFSDVTASVCNSSKVDCEIDKVDLVFLMDGSTSIQ 1012

Query: 1042 -SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTL 1100
             + F  +KEF+  VV+  DV  +RVR+   Q+SD   PEF L +++ ++++   +  +  
Sbjct: 1013 PNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIGEKEISFQIENIKQ 1072

Query: 1101 LGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGA 1160
            + G T + GAAL  V  +      GSRI  G PQ+L+VLT  +S D+V   +  ++  G 
Sbjct: 1073 IFGNT-HIGAALREV-EHYFRPDMGSRINTGTPQVLLVLTDGQSQDEVAQAAEALRHRGI 1130

Query: 1161 VPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERV 1205
                +GIG+ D  ++  I+   +  + +  F +L  V + I   +
Sbjct: 1131 DIYSVGIGDVDDQQLIQITGTAEKKLTVHNFDELKKVNKRIVRNI 1175



 Score =  382 bits (980), Expect = e-105
 Identities = 299/1096 (27%), Positives = 533/1096 (48%), Gaps = 82/1096 (7%)

Query: 38   ADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYR 97
            AD++FL+D S    EE+F  ++ FL + V +L + EN     LV ++        L+   
Sbjct: 228  ADVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGI 287

Query: 98   TKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDG 157
             K EVL HI N+S   G   TG  ++ + +   +   GSR   GVPQ+ V++T   S+D 
Sbjct: 288  NKSEVLQHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSRKNQGVPQIAVLVTHRDSEDN 347

Query: 158  LALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENF--------TSLHDI 209
            +   +  L+   V +F +G+E A +  L++IAS P   ++  L+ F        T L  +
Sbjct: 348  VTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAEQYVSKLKTFADLAAHNQTFLKKL 407

Query: 210  VGNLVSCVHSSVSPERAGDTETLKD-ITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNL 268
               +   V  SV  ER   TETLK      + ADI  LIDGS +T + +F  +  FL  +
Sbjct: 408  RNQITHTV--SVFSER---TETLKSGCVDTEEADIYLLIDGSGSTQATDFHEMKTFLSEV 462

Query: 269  LEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDF 328
            +    I   ++RVG VQ++D     F ++ YS K  +  A++ +   GG   N G AL+F
Sbjct: 463  VGMFNIAPHKVRVGAVQYADSWDLEFEINKYSNKQDLGKAIENIRQMGGN-TNTGAALNF 521

Query: 329  VVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAE 388
             +     +    +    VP  LV+++ G S D I      L++  +  + +G + A++ +
Sbjct: 522  TLS--LLQKAKKQRGNKVPCHLVVLTNGMSKDSILEPANRLREEHIRVYAIGIKEANQTQ 579

Query: 389  LQHIATDDNLVFTVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVF 448
            L+ IA ++  V+ V +F +  D++ +++  I                 +  +  K DI+F
Sbjct: 580  LREIAGEEKRVYYVHDFDALKDIRNQVVQEI--------------CTEEACKEMKADIMF 625

Query: 449  LVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREV 508
            LVD S ++G  NF+ ++ F+  ++ + +IG D +Q+ V Q++D  + EF  N   ++ ++
Sbjct: 626  LVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINKEEFQLNRFMSQSDI 685

Query: 509  ITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQP 568
              A+ +M  + G    TGSAL FV +  F+ + G  A   I K L+LIT G++ D + +P
Sbjct: 686  SNAIDQMAHI-GQTTLTGSALSFV-SQYFSPTKG--ARPNIRKFLILITDGEAQDIVKEP 741

Query: 569  AQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPL--QGMLPGLLAPLRT 626
            A  L++  ++ +++G  G++  +LEEI+    +VF    F         ++ G+ +P   
Sbjct: 742  AVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVENFDILQRIEDDLVFGICSPREE 801

Query: 627  LSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDT 686
                  +     D++F++D S ++    +  ++DF++ LV   D+G + +R G ++++D 
Sbjct: 802  CKRIEVL-----DVVFVIDSSGSIDYDEYNIMKDFMIGLVKKADVGKNQVRFGALKYADD 856

Query: 687  PVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANH-FTEAGGSRIREHVPQ 745
            P   F L+ + TK +++  L+  Q  GGS   T +A +  +++H FTEA GSR+ + VPQ
Sbjct: 857  PEVLFYLDDFGTKLEVISVLQNDQAMGGS---TYTAEALGFSDHMFTEARGSRLNKGVPQ 913

Query: 746  LLLLLTAGQSEDS--YLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFS 803
            +L+++T G+S D+      A AL   GIL   VG   AN  EL  +A +    + ++ F 
Sbjct: 914  VLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVELLAMAGSSDKYFFVETFG 973

Query: 804  SLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANL-VGQFPVVRDFLYKI 862
             L  +   +   +        E         K D++FL DGS ++    F  +++FL  +
Sbjct: 974  GLKGIFSDVTASVCNSSKVDCE-------IDKVDLVFLMDGSTSIQPNDFKKMKEFLASV 1026

Query: 863  IDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDY 922
            + + +V     RI  AQ+SD    E        + EI   ++ +K   G   ++G AL  
Sbjct: 1027 VQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIGEKEISFQIENIKQIFGNT-HIGAALRE 1085

Query: 923  AQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAE 982
             + Y F    GSRI  G  Q L++L  G+S D V   A  L+  G+  +     + D  +
Sbjct: 1086 VEHY-FRPDMGSRINTGTPQVLLVLTDGQSQDEVAQAAEALRHRGIDIYSVGIGDVDDQQ 1144

Query: 983  LEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGS----- 1037
            L QI  +    L   +  ++  ++ +IV  + +    +   V    DVV   D S     
Sbjct: 1145 LIQITGTAEKKLTVHNFDELKKVNKRIVRNICTTAGESNCFV----DVVVGFDVSTQEKG 1200

Query: 1038 EGVRSGFPLLKEFVQRVVE--------SLDVG---QDRVRVAVVQYSDRTRPEFYLNSYM 1086
            + +  G P ++ ++Q ++         S +VG   Q  V   V    ++  P+F + S  
Sbjct: 1201 QTLLEGQPWMETYLQDILRAISSLNGVSCEVGTETQVSVAFQVTNAMEKYSPKFEIYS-- 1258

Query: 1087 NKQDVVNAVRQLTLLG 1102
              ++++N+++ +T+ G
Sbjct: 1259 --ENILNSLKDITVKG 1272



 Score =  154 bits (390), Expect = 1e-36
 Identities = 141/559 (25%), Positives = 251/559 (44%), Gaps = 36/559 (6%)

Query: 1435 ADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYR 1494
            AD+VFL+DSS+ +    F  ++ F+++++  L I   K RV + Q+S+ +  EF+L T++
Sbjct: 26   ADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFK 85

Query: 1495 SQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQD 1554
             ++P+L+ +R+     G  L  GKAL+   R  F   A  R +   P  LV++   +S+D
Sbjct: 86   GRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVLASSESED 145

Query: 1555 DVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFG 1614
            +V   ++ +R  G+  + VG +      L+ +    +  F +R  R+L    + + +   
Sbjct: 146  NVEEASKALRKDGVKIISVGVQKASEENLKAMATS-QFHFNLRTVRDLSMFSQNMTHIIK 204

Query: 1615 PSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGD 1674
                       D    +      AD+VFLLD SIN   ++F  +  F+ E V  +    +
Sbjct: 205  DVIKYKEGAVDDIFVEACQGPSMADVVFLLDMSINGSEENFDYLKGFLEESVSALDIKEN 264

Query: 1675 SIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPE 1734
             ++VGLV Y+++      L     K +++  I  +  + G+ A T   ++ LR   F   
Sbjct: 265  CMRVGLVAYSNETKVINSLSMGINKSEVLQHIQNLSPRTGK-AYTGAAIKKLRKEVFSAR 323

Query: 1735 AGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSA 1794
             GSR +Q VPQIA ++T   S ++    ++ L + GV +F +G+      ++ KIAS+ A
Sbjct: 324  NGSRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPA 383

Query: 1795 TAF----------RVGNVQELSELSEQVLET--LHDAMHETLCPGVTDAAKACNLDVILG 1842
              +             N   L +L  Q+  T  +     ETL  G  D  +A ++ +++ 
Sbjct: 384  EQYVSKLKTFADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSGCVDTEEA-DIYLLID 442

Query: 1843 FDGSRDQNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFD 1902
              GS     F   K F S+V  + N                 VRV  V    S  +E F+
Sbjct: 443  GSGSTQATDFHEMKTFLSEVVGMFNIAPH------------KVRVGAVQYADSWDLE-FE 489

Query: 1903 FDEY--QPEMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPD-SVKVVIH---FTDGAD 1956
             ++Y  + ++ +   N+R       T   L   L+  +++      KV  H    T+G  
Sbjct: 490  INKYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSLLQKAKKQRGNKVPCHLVVLTNGMS 549

Query: 1957 GDLADLHRASENLRQEGVR 1975
             D   +   +  LR+E +R
Sbjct: 550  KD--SILEPANRLREEHIR 566



 Score = 52.4 bits (124), Expect = 7e-06
 Identities = 78/362 (21%), Positives = 140/362 (38%), Gaps = 65/362 (17%)

Query: 39   DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDF----HFALVQFNGNPHTEFLLN 94
            +++F +D S  + E+ F+ ++E +  +V+ + V EN      H A++ +N +       +
Sbjct: 1757 ELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYNSHARHLVRFS 1816

Query: 95   TYRTKQEVLSHISNMSY--IGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDG 152
                K ++L  I  + Y     + + G+ + +I ++   +      G    ++    + G
Sbjct: 1817 DAYKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKRTL---PGAHTRKIATFFSSG 1873

Query: 153  HSKDGLALPSAELKSADVNVFAIGVEDA------------DEGALKEI---ASEPLNMHM 197
             S D  ++ +A ++   + +  + +  +            D G  + I   +       +
Sbjct: 1874 QSADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAIDDTGTFQVIVVPSGADYIPAL 1933

Query: 198  FNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVN 257
              L+  T  +D+     SC  +   P              Q   D  FL+D S N GS  
Sbjct: 1934 ERLQRCTFCYDVCKPDASCDQARPPP-------------VQSYMDAAFLLDASRNMGSAE 1980

Query: 258  FAVILDFLVNLLEKLPI----GTQQIRVGVVQFSDEP------------RTMFSLDTYST 301
            F  I  FL  LL+   I     T      V   S  P            R  F+L TY +
Sbjct: 1981 FEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEFNLTTYRS 2040

Query: 302  ----KAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGP 357
                K  V  +VK L    G+ A IG AL + ++N F      R      +V+ +ISAG 
Sbjct: 2041 KRLMKRHVHESVKQL---NGD-AFIGHALQWTLDNVFLSTPNLRRN----KVIFVISAGE 2092

Query: 358  SS 359
            +S
Sbjct: 2093 TS 2094



 Score = 49.3 bits (116), Expect = 6e-05
 Identities = 84/412 (20%), Positives = 160/412 (38%), Gaps = 72/412 (17%)

Query: 629  GTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVG--------- 679
            G PE   +  +++F LD S +V +  F  +++ +  LV  + +  ++  VG         
Sbjct: 1747 GKPECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYN 1806

Query: 680  -----LVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGS-GLNTGSALSYVYANHFTE 733
                 LV+FSD             KS +L  +  +  +  S     G A+ ++  N F  
Sbjct: 1807 SHARHLVRFSDA----------YKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKR 1856

Query: 734  AGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQ-IAFN 792
               +    H  ++    ++GQS D++     A+    +    V  + +N   + +  A +
Sbjct: 1857 ---TLPGAHTRKIATFFSSGQSADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAID 1913

Query: 793  PS----LVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQP---ESKRDILFLFDGS 845
             +    ++ +      +PAL +         V         A+P   +S  D  FL D S
Sbjct: 1914 DTGTFQVIVVPSGADYIPALERLQRCTFCYDVCKPDASCDQARPPPVQSYMDAAFLLDAS 1973

Query: 846  ANL-VGQFPVVRDFLYKIIDELNVKPE------GTRIAVAQYS----------DDVKVES 888
             N+   +F  +R FL  ++D   + PE      G R+A+  ++            V+ E 
Sbjct: 1974 RNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEF 2033

Query: 889  RFDEHQSKPEILNLVKRMKIKTGKALN----LGYALDYAQRYIFVKSAGSRIEDGVLQFL 944
                ++SK     L+KR   ++ K LN    +G+AL +    +F+ +   R        +
Sbjct: 2034 NLTTYRSK----RLMKRHVHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRNK-----V 2084

Query: 945  VLLVAGRSSDRVDG-----PASNLKQSGVVPFIFQAKNA-DPAELEQIVLSP 990
            + +++   +  +DG      +   K  G   F+F      D  ELE +   P
Sbjct: 2085 IFVISAGETSHLDGEILKKESLRAKCQGYALFVFSLGPIWDDKELEDLASHP 2136


>gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]
          Length = 2526

 Score = 1032 bits (2668), Expect = 0.0
 Identities = 706/2188 (32%), Positives = 1101/2188 (50%), Gaps = 127/2188 (5%)

Query: 639  DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQT 698
            D++FL+D S ++G  +FP+V+ F+  ++NSL I  +  RV L Q+SD   +EF L+T++ 
Sbjct: 30   DVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHSEFHLSTFKG 89

Query: 699  KSDILGHLRQ-LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSED 757
            +S +L HL++  Q  GGS L  G AL   +  +F+     R R+  P +L++L + +SED
Sbjct: 90   RSPMLNHLKKNFQFIGGS-LQIGKALQEAHRTYFSAPINGRDRKQFPPILVVLASAESED 148

Query: 758  SYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYL--MDDFSSLPALPQQLIQP 815
               +A+ AL + G+    VG  +A++  L+ +A +     L  + D S+      Q+I+ 
Sbjct: 149  EVEEASKALQKDGVKIISVGVQKASEENLKAMATSHFHFNLRTIRDLSTFSQNMTQIIKD 208

Query: 816  LTTYVSGGVE-----EVPLA-QPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVK 869
            +T Y  G V+       P++ Q +S  D++FL D S    G    ++ FL  I   ++VK
Sbjct: 209  VTKYKEGAVDADMQVHFPISCQKDSLADLVFLVDESLGTGGNLRHLQTFLENITSSMDVK 268

Query: 870  PEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFV 929
                R+ +  YS+  K  S      ++ E    +K + I+ GK+ N G A+D  +R  F 
Sbjct: 269  ENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQIKNLSIQVGKS-NTGAAIDQMRRDGFS 327

Query: 930  KSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLS 989
            +S GSR   GV Q  VL+    S D V   A NL+   V  F    + A+  +LE+IV  
Sbjct: 328  ESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNLRLEDVNVFALSIQGANNTQLEEIVSY 387

Query: 990  PAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSG----------------EKDVVFL 1033
            P       +L    DL       LK + N   + +S                 E D+ FL
Sbjct: 388  PPE-QTISTLKSYADLETYSTKFLKKLQNEIWSQISTYAEQRNLDKTGCVDTKEADIHFL 446

Query: 1034 LDGSEGVRSG-FPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVV 1092
            +DGS  ++   F  +K F+  V E   +G D+VRV VVQYSD T  EFY+  Y N  D+ 
Sbjct: 447  IDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFYITDYSNDIDLR 506

Query: 1093 NAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPS 1152
             A+  +  L G T  TG AL+++L+ I+ +    R+++ VP  LIVLT   S D V  P+
Sbjct: 507  KAIFNIKQLTGGT-YTGKALDYILQ-IIKNGMKDRMSK-VPCYLIVLTDGMSTDRVVEPA 563

Query: 1153 VVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQ-QVISERVTQLTRE 1211
              ++        +GIG A+  E+Q I+   +       F  L +++ +V+ E   +   E
Sbjct: 564  KRLRAEQITVHAVGIGAANKIELQEIAGKEERVSFGQNFDALKSIKNEVVREICAEKGCE 623

Query: 1212 ELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTR 1270
            ++                 K D++FL+D S S G E F+ ++  ++ L+  + +G D T+
Sbjct: 624  DM-----------------KADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGADKTQ 666

Query: 1271 VAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGS 1330
            + V+QFSD  K EF LN + ++ E+ +A+ R+       +  G AL +V +  F    G+
Sbjct: 667  IGVVQFSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTLT-GKALNFVGQ-YFTHSKGA 724

Query: 1331 RIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIA-RNADQEELVKISLSPEYVF 1389
            R+  G  +FL+LI+ G + D+V DPA  L+   V  F++   NA++ +L +IS     VF
Sbjct: 725  RL--GAKKFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGDSSLVF 782

Query: 1390 SVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRP 1449
             V  F  L +LE+KL+  +  L   +   LL               D+VF++D S  ++ 
Sbjct: 783  HVENFDHLKALERKLIFRVCALHDCKRITLL---------------DVVFVLDHSGSIKK 827

Query: 1450 DGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLR 1509
                H+ +    +V++ ++G  +V+ G +++S+     FYL TY +++ +++ +R+ R  
Sbjct: 828  QYQDHMINLTIHLVKKADVGRDRVQFGALKYSDQPNILFYLNTYSNRSAIIENLRKRRDT 887

Query: 1510 GGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQD--DVSRFAQVIRSSG 1567
            GG+   T KAL+  A  LF +  GSRI+  V Q L+++  G+S D   ++  A  +R+ G
Sbjct: 888  GGNTY-TAKALKH-ANALFTEEHGSRIKQNVKQMLIVITDGESHDHDQLNDTALELRNKG 945

Query: 1568 IVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDT 1627
            I    VG    ++ EL+ +  +      V  F +L ++   +               + T
Sbjct: 946  ITIFAVGVGKANQKELEGMAGNKNNTIYVDNFDKLKDVFTLVQER------------MCT 993

Query: 1628 PPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDP 1687
              P     ++AD++FL DGS       F  +  F+S+++D        +++G+ Q+ S+ 
Sbjct: 994  EAPEVCHLQEADVIFLCDGSDRVSNSDFVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSNY 1053

Query: 1688 TDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIA 1747
                 LK+  TK Q    I  V   GG        L+ +  N F   AG R +  VPQ  
Sbjct: 1054 QSIIELKNSLTKTQWKTQIQNVSKSGG-FPRIDFALKKVS-NMFNLHAGGRRNAGVPQTL 1111

Query: 1748 FVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELS- 1806
             VIT G    D  D    L   G+ V  +G+ ++  E +  I  NS       +  +L  
Sbjct: 1112 VVITSGDPRYDVADAVKTLKDLGICVLVLGIGDVYKEHLLPITGNSEKIITFQDFDKLKN 1171

Query: 1807 -ELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGS---RDQNVFVAQKGFESKV 1862
             ++ ++++  +  +  +T           C +D+++GFD S   + Q +F      ES +
Sbjct: 1172 VDVKKRIIREICQSCGKT----------NCFMDIVVGFDISTHVQGQPLFQGHPQLESYL 1221

Query: 1863 DAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQHP 1922
              IL  IS +  VSC  G    V ++   N+  G    F    YQ  + +    +    P
Sbjct: 1222 PGILEDISSIKGVSCGAGTEAQVSLAFKVNSDQGFPAKFQI--YQKAVFDSLLQVNVSGP 1279

Query: 1923 YVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDL-ADLHRASENLRQEGVRALILVG 1981
              L    L+   + F+  S    +V++ F+DG   +    L   S+ LR+ G+ AL++V 
Sbjct: 1280 THLNAQFLRSLWDTFKDKSASRGQVLLIFSDGLQSESNIMLENQSDRLREAGLDALLVVS 1339

Query: 1982 LERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQRG 2041
            L    + E     EFG+ F Y   L + + +L  +L++ L NIAE+ CC   CKC G  G
Sbjct: 1340 LNTTAHHE-FSSFEFGKRFDYRTHLTIGMRELGKKLSQYLGNIAERTCCCTFCKCPGIPG 1398

Query: 2042 DRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPG 2101
              G  G    KG  G  G RG+ G++G PG RG  G  G +G  GCPG  G KG +GF G
Sbjct: 1399 PHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFSG 1458

Query: 2102 EKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPG 2161
             KG  G+ G+DGLDGE+G  G PG  GEKG+PG +G  G RG  G+ G+ G  GDPGNPG
Sbjct: 1459 PKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPG 1518

Query: 2162 QDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFE 2221
            Q++  +G KG  G+ G  G  G+ GV G P   G  G  G+RG  G  G  G PG  G  
Sbjct: 1519 QNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGTL 1578

Query: 2222 GEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPK 2281
            G +G +G QG  G  G  G  G QG  GP+GS G  GA G  GR G LG+KGEPG PG  
Sbjct: 1579 GAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDL 1638

Query: 2282 GGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRG 2341
            G +G  G RG  GD G  G G  GR+G KG RGFPG  G KG+ G PG+ G  GPKG RG
Sbjct: 1639 GPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRG 1698

Query: 2342 RRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSI-DQCALIQSIKDKCPCCYGPLECPVFP 2400
                 G  G  G +G PG PG  G KG  G  +  QC LI+ +++  PC     +CP +P
Sbjct: 1699 LALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCDLIRFLREHSPC--WKEKCPAYP 1756

Query: 2401 TELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRF 2460
            TEL FALD S  V +++F + RD++ SIVNDL I E+NCP GARVA+V+YN+  +  IR+
Sbjct: 1757 TELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNSGTSYLIRW 1816

Query: 2461 ADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPT 2520
            +D  RK  LL ++  ++   T++ + +  AM FV RN FKR   G  +R+VAVFFSN  T
Sbjct: 1817 SDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYAGANVRRVAVFFSNGQT 1876

Query: 2521 RASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLEN 2580
             +   +  A ++ S   I+P      E R  + A   +NT     + +P   +    LE 
Sbjct: 1877 ASRSSIITATMEFSALDISPTVFAFDE-RVFLEAFGFDNTGTFQVIPVPPNGE-NQTLER 1934

Query: 2581 VLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKK 2640
            +  C +C D C    +C   ++ P          D  +D+ F++D++      +F  +K 
Sbjct: 1935 LRRCALCYDKC-FPNACIREAFLP---------EDSYMDVVFLIDNSRNIAKDEFKAVKA 1984

Query: 2641 YIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVD 2700
             ++ ++   +++ DP  S    R+A++ ++P ES     M  VK EF    Y ++  + +
Sbjct: 1985 LVSSVIDNFNIASDPLISDSGDRIALLSYSPWES-SRRKMGTVKTEFDFITYDNQLLMKN 2043

Query: 2701 FLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVIL 2760
             +     QL G   +G A+ +T EN+F   P  R  K++ ++  GE  E++ E  + + L
Sbjct: 2044 HIQTSFQQLNGEATIGRALLWTTENLFPETPYLRKHKVIFVVSAGENYERK-EFVKMMAL 2102

Query: 2761 QAKCKGY--FFVVLGIGRKVNIKEVYTF 2786
            +AKC+GY  F + LG  RK +++E+ ++
Sbjct: 2103 RAKCQGYVIFVISLGSTRKDDMEELASY 2130



 Score =  416 bits (1070), Expect = e-115
 Identities = 316/1152 (27%), Positives = 574/1152 (49%), Gaps = 56/1152 (4%)

Query: 38   ADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYR 97
            AD++FLVDSS  +G + F  V+ F+  ++ SL +  N +  AL Q++   H+EF L+T++
Sbjct: 29   ADVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHSEFHLSTFK 88

Query: 98   TKQEVLSHI-SNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKD 156
             +  +L+H+  N  +IGG+ Q GK L+   +++ +     R     P ++VVL    S+D
Sbjct: 89   GRSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRKQFPPILVVLASAESED 148

Query: 157  GLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSC 216
             +   S  L+   V + ++GV+ A E  LK +A+   + ++  + + ++    +  ++  
Sbjct: 149  EVEEASKALQKDGVKIISVGVQKASEENLKAMATSHFHFNLRTIRDLSTFSQNMTQIIKD 208

Query: 217  VHSSVSPERAGDTETLKDITAQDS--ADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPI 274
            V          D +    I+ Q    AD++FL+D S  TG  N   +  FL N+   + +
Sbjct: 209  VTKYKEGAVDADMQVHFPISCQKDSLADLVFLVDESLGTGG-NLRHLQTFLENITSSMDV 267

Query: 275  GTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHF 334
                +R+G++ +S+  +T+  L + +T+++    +K L    G+ +N G A+D +  + F
Sbjct: 268  KENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQIKNLSIQVGK-SNTGAAIDQMRRDGF 326

Query: 335  TRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIAT 394
            + + GSR  +GVPQ+ VL++  PS DE+    + L+   V  F L  Q A+  +L+ I +
Sbjct: 327  SESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNLRLEDVNVFALSIQGANNTQLEEIVS 386

Query: 395  DDNLVFTVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIVTQ-------VIEVNKRDIV 447
                  T+   +S+ DL+     ++  + Q  I  +  T   Q        ++  + DI 
Sbjct: 387  YPP-EQTISTLKSYADLETYSTKFLKKL-QNEIWSQISTYAEQRNLDKTGCVDTKEADIH 444

Query: 448  FLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKRE 507
            FL+DGSS++    F  I+ F+ +V +   IG D ++V V QY+D    EFY   +    +
Sbjct: 445  FLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFYITDYSNDID 504

Query: 508  VITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQ 567
            +  A+  +K L G   YTG ALD++   +  +    R ++ +P  L+++T G S D + +
Sbjct: 505  LRKAIFNIKQLTGGT-YTGKALDYIL-QIIKNGMKDRMSK-VPCYLIVLTDGMSTDRVVE 561

Query: 568  PAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTL 627
            PA+ L+   I   A+G   A++ EL+EIA     V     F A  L+ +   ++  +   
Sbjct: 562  PAKRLRAEQITVHAVGIGAANKIELQEIAGKEERVSFGQNFDA--LKSIKNEVVREICAE 619

Query: 628  SGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTP 687
             G  ++   K DI+FL+D S ++G  NF  ++ F+ NL+  + IG D  ++G+VQFSD  
Sbjct: 620  KGCEDM---KADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGADKTQIGVVQFSDKT 676

Query: 688  VTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLL 747
              EF LN Y T+ +I   + ++ L    G  TG AL++V   +FT + G+R+     + L
Sbjct: 677  KEEFQLNRYFTQQEISDAIDRMSLI-NEGTLTGKALNFV-GQYFTHSKGARL--GAKKFL 732

Query: 748  LLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPA 807
            +L+T G ++D     A  L    +  F VG   AN+++LE+I+ + SLV+ +++F  L A
Sbjct: 733  ILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGDSSLVFHVENFDHLKA 792

Query: 808  LPQQLIQPLTTYVSGGVEEVPLAQPESKR----DILFLFDGSANLVGQF-PVVRDFLYKI 862
            L ++LI  +             A  + KR    D++F+ D S ++  Q+   + +    +
Sbjct: 793  LERKLIFRV------------CALHDCKRITLLDVVFVLDHSGSIKKQYQDHMINLTIHL 840

Query: 863  IDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEIL-NLVKRMKIKTGKALNLGYALD 921
            + + +V  +  +    +YSD   +    + + ++  I+ NL KR    TG       AL 
Sbjct: 841  VKKADVGRDRVQFGALKYSDQPNILFYLNTYSNRSAIIENLRKRR--DTGGNTYTAKALK 898

Query: 922  YAQRYIFVKSAGSRIEDGVLQFLVLLVAGRS--SDRVDGPASNLKQSGVVPFIFQAKNAD 979
            +A   +F +  GSRI+  V Q L+++  G S   D+++  A  L+  G+  F      A+
Sbjct: 899  HANA-LFTEEHGSRIKQNVKQMLIVITDGESHDHDQLNDTALELRNKGITIFAVGVGKAN 957

Query: 980  PAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVS-GEKDVVFLLDGSE 1038
              ELE +  +    +  ++  K+ D+   +    + +   AP      E DV+FL DGS+
Sbjct: 958  QKELEGMAGNKNNTIYVDNFDKLKDVFTLV---QERMCTEAPEVCHLQEADVIFLCDGSD 1014

Query: 1039 GV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQ 1097
             V  S F  +  F+  ++++ D+   R+++ + Q+    +    L + + K      ++ 
Sbjct: 1015 RVSNSDFVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSNYQSIIELKNSLTKTQWKTQIQN 1074

Query: 1098 LTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKR 1157
            ++  GG  P    AL+ V  N+    AG R   GVPQ L+V+T+     DV +    +K 
Sbjct: 1075 VSKSGG-FPRIDFALKKV-SNMFNLHAGGRRNAGVPQTLVVITSGDPRYDVADAVKTLKD 1132

Query: 1158 GGAVPIGIGIGN 1169
             G   + +GIG+
Sbjct: 1133 LGICVLVLGIGD 1144



 Score =  299 bits (766), Expect = 3e-80
 Identities = 273/1049 (26%), Positives = 483/1049 (46%), Gaps = 90/1049 (8%)

Query: 1020 APAPVSGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRP 1078
            +P P     DVVFL+D S+ +    FP +K F+ +++ SL +  ++ RVA+ QYSD    
Sbjct: 21   SPGPGPVYADVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHS 80

Query: 1079 EFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIV 1138
            EF+L+++  +  ++N +++     G +   G AL+   R    +    R  +  P +L+V
Sbjct: 81   EFHLSTFKGRSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRKQFPPILVV 140

Query: 1139 LTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQ 1198
            L +  S D+V   S  +++ G   I +G+  A    ++ ++    F   + T R L T  
Sbjct: 141  LASAESEDEVEEASKALQKDGVKIISVGVQKASEENLKAMA-TSHFHFNLRTIRDLSTFS 199

Query: 1199 QVISERVTQLTREELSRLQPVLQ---PLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLI 1255
            Q +++ +  +T+ +   +   +Q   P+ S       D+VFL+D S   G   ++++T +
Sbjct: 200  QNMTQIIKDVTKYKEGAVDADMQVHFPI-SCQKDSLADLVFLVDESLGTGGNLRHLQTFL 258

Query: 1256 ERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNA 1315
            E +   +DV  +  R+ ++ +S+  K    L + +++ E Q  ++ L  + G+  N G A
Sbjct: 259  ENITSSMDVKENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQIKNLSIQVGKS-NTGAA 317

Query: 1316 LEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI----AR 1371
            ++ + R+ F    GSR  +GVPQ  VL++   SDDEV D A+ L+   V  F +    A 
Sbjct: 318  IDQMRRDGFSESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNLRLEDVNVFALSIQGAN 377

Query: 1372 NADQEELVKISLSPEYVFS-VSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPP-A 1429
            N   EE+V  S  PE   S + ++ +L +   K L  +      QI              
Sbjct: 378  NTQLEEIV--SYPPEQTISTLKSYADLETYSTKFLKKLQNEIWSQISTYAEQRNLDKTGC 435

Query: 1430 VESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFY 1489
            V++  ADI FLID S  ++   F  I+ F+  +    +IGP KVRVGVVQ+S+D   EFY
Sbjct: 436  VDTKEADIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFY 495

Query: 1490 LKTYRSQAPVLDAIRRLR-LRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVL 1548
            +  Y +   +  AI  ++ L GG+   TGKAL+++ +   +K+        VP +L+++ 
Sbjct: 496  ITDYSNDIDLRKAIFNIKQLTGGT--YTGKALDYILQ--IIKNGMKDRMSKVPCYLIVLT 551

Query: 1549 GGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEER 1608
             G S D V   A+ +R+  I    VG    ++ ELQ I      V   + F  L +I+  
Sbjct: 552  DGMSTDRVVEPAKRLRAEQITVHAVGIGAANKIELQEIAGKEERVSFGQNFDALKSIKNE 611

Query: 1609 IMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDT 1668
            ++                       E  KADI+FL+D S +   ++F+++  F+  ++  
Sbjct: 612  VVREICAEKGC--------------EDMKADIMFLVDSSWSIGNENFRKMKIFMKNLLTK 657

Query: 1669 VYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINK--VVYKG---GRHANTKVGL 1723
            +    D  Q+G+VQ++    +EF L  + T+++I DAI++  ++ +G   G+  N  VG 
Sbjct: 658  IQIGADKTQIGVVQFSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTLTGKALNF-VG- 715

Query: 1724 EHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDS 1783
                  +F    G+RL  +  +   +IT G + +D +D +  L  + V +F+VGV N + 
Sbjct: 716  -----QYFTHSKGARLGAK--KFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANR 768

Query: 1784 EEVGKIASNSATAFRVGNVQELSELSEQVLE---TLHDAMHETLCPGVTDAAKACNLDVI 1840
             ++ +I+ +S+  F V N   L  L  +++     LHD    TL            LDV+
Sbjct: 769  SQLEEISGDSSLVFHVENFDHLKALERKLIFRVCALHDCKRITL------------LDVV 816

Query: 1841 LGFDGSRDQNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEA 1900
               D S        +K ++   D ++N    +H V  +      V+   +  +   P   
Sbjct: 817  FVLDHSGS-----IKKQYQ---DHMIN--LTIHLVKKADVGRDRVQFGALKYSDQ-PNIL 865

Query: 1901 FDFDEY--QPEMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVK-----VVIHFTD 1953
            F  + Y  +  ++E  R  R       T   LK     F +     +K     ++I  TD
Sbjct: 866  FYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKHANALFTEEHGSRIKQNVKQMLIVITD 925

Query: 1954 GADGDLADLHRASENLRQEGVRALILVGLERVVNLERLMHLEFGRGFMYDRPLRLNLLDL 2013
            G   D   L+  +  LR +G+  +  VG+ +    E    LE G     +  + ++  D 
Sbjct: 926  GESHDHDQLNDTALELRNKGI-TIFAVGVGKANQKE----LE-GMAGNKNNTIYVDNFD- 978

Query: 2014 DYELAEQLDNIAEKACCGVPCKCSGQRGD 2042
              +L +    + E+ C   P  C  Q  D
Sbjct: 979  --KLKDVFTLVQERMCTEAPEVCHLQEAD 1005



 Score =  142 bits (359), Expect = 4e-33
 Identities = 103/386 (26%), Positives = 181/386 (46%), Gaps = 18/386 (4%)

Query: 31   DVKNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTE 90
            D K     D++F++D S +I +++   +      +VK   VG +   F  ++++  P+  
Sbjct: 806  DCKRITLLDVVFVLDHSGSIKKQYQDHMINLTIHLVKKADVGRDRVQFGALKYSDQPNIL 865

Query: 91   FLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLT 150
            F LNTY  +  ++ ++      GG   T K L++   +  T+  GSR    V Q+++V+T
Sbjct: 866  FYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKH-ANALFTEEHGSRIKQNVKQMLIVIT 924

Query: 151  DG--HSKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHD 208
            DG  H  D L   + EL++  + +FA+GV  A++  L+ +A    N     ++NF  L D
Sbjct: 925  DGESHDHDQLNDTALELRNKGITIFAVGVGKANQKELEGMAGNKNN--TIYVDNFDKLKD 982

Query: 209  IVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNL 268
            +   LV     + +PE          +     AD+IFL DGS+   + +F  +  FL +L
Sbjct: 983  VF-TLVQERMCTEAPE----------VCHLQEADVIFLCDGSDRVSNSDFVTMTTFLSDL 1031

Query: 269  LEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDF 328
            ++   I +Q++++G+ QF    +++  L    TK Q    ++ +  +GG    I  AL  
Sbjct: 1032 IDNFDIQSQRMKIGMAQFGSNYQSIIELKNSLTKTQWKTQIQNVSKSGG-FPRIDFALK- 1089

Query: 329  VVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAE 388
             V N F    G R   GVPQ LV+I++G    ++   V  LK   +    LG     +  
Sbjct: 1090 KVSNMFNLHAGGRRNAGVPQTLVVITSGDPRYDVADAVKTLKDLGICVLVLGIGDVYKEH 1149

Query: 389  LQHIATDDNLVFTVPEFRSFGDLQEK 414
            L  I  +   + T  +F    ++  K
Sbjct: 1150 LLPITGNSEKIITFQDFDKLKNVDVK 1175



 Score =  101 bits (252), Expect = 1e-20
 Identities = 62/219 (28%), Positives = 110/219 (50%), Gaps = 1/219 (0%)

Query: 2618 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2677
            +D+AF++D+++     +F E+K +I  ++    ++P P  S    RVAV+ ++P   + N
Sbjct: 2290 MDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPN 2349

Query: 2678 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLK 2737
                PV +EF L  Y S  ++   L     QL G   +G A+++TI+NVF   PN R  K
Sbjct: 2350 TEECPVYLEFDLVTYNSIHQMKHHLQDSQ-QLNGDVFIGHALQWTIDNVFVGTPNLRKNK 2408

Query: 2738 IVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKL 2797
            ++ ++  GE      +  + V L+AKC+GY   V   G K N KE+   AS P D     
Sbjct: 2409 VIFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHNDKELEELASHPLDHHLVQ 2468

Query: 2798 VDKSTELNEEPLMRFGRLLPSFVSSENAFYLSPDIRKQC 2836
            + ++ + +   +++F +     +      Y + D++  C
Sbjct: 2469 LGRTHKPDWNYIIKFVKPFVHLIRRAINKYPTEDMKATC 2507



 Score = 55.1 bits (131), Expect = 1e-06
 Identities = 74/400 (18%), Positives = 151/400 (37%), Gaps = 59/400 (14%)

Query: 39   DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGEND----FHFALVQFNGNPHTEFLLN 94
            +++F +D+S+ + EE F   R+ +  +V  L + EN+       A+V +N         +
Sbjct: 1758 ELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNSGTSYLIRWS 1817

Query: 95   TYRTKQEVLSHISNMSYIGGT--NQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDG 152
             Y  K+++L  +S + Y   T     G  + ++ ++   +   + AG  V +V V  ++G
Sbjct: 1818 DYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKR---TYAGANVRRVAVFFSNG 1874

Query: 153  H--SKDGLALPSAELKSADVNVFAIGVEDA--------DEGALKEIASEPLNMHMFNLEN 202
               S+  +   + E  + D++      ++         D     ++   P N     LE 
Sbjct: 1875 QTASRSSIITATMEFSALDISPTVFAFDERVFLEAFGFDNTGTFQVIPVPPNGENQTLER 1934

Query: 203  FTSLHDIVGNLV--SCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAV 260
                          +C+  +  PE                 D++FLID S N     F  
Sbjct: 1935 LRRCALCYDKCFPNACIREAFLPE-------------DSYMDVVFLIDNSRNIAKDEFKA 1981

Query: 261  ILDFLVNLLEKLPIGTQQI------RVGVVQFS---------DEPRTMFSLDTYSTKAQV 305
            +   + ++++   I +  +      R+ ++ +S            +T F   TY  +  +
Sbjct: 1982 VKALVSSVIDNFNIASDPLISDSGDRIALLSYSPWESSRRKMGTVKTEFDFITYDNQLLM 2041

Query: 306  LGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYG 365
               ++         A IG AL +  EN F      R      +V+ ++SAG + +   + 
Sbjct: 2042 KNHIQTSFQQLNGEATIGRALLWTTENLFPETPYLRKH----KVIFVVSAGENYERKEFV 2097

Query: 366  VVALKQAS-----VFSFGLGA-QAASRAELQHIATDDNLV 399
             +   +A      +F   LG+ +     EL     D +L+
Sbjct: 2098 KMMALRAKCQGYVIFVISLGSTRKDDMEELASYPLDQHLI 2137



 Score = 52.8 bits (125), Expect = 5e-06
 Identities = 81/390 (20%), Positives = 155/390 (39%), Gaps = 54/390 (13%)

Query: 242  DIIFLIDGSNNTGSVNFAVILDFLVNLLEKL-------PIGTQQIRVGVVQFSDEPRTMF 294
            +++F +D S +    +F    D + +++  L       P+G    RV +V ++     + 
Sbjct: 1758 ELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGA---RVAMVSYNSGTSYLI 1814

Query: 295  SLDTYSTKAQVLGAVKALGFAGG-ELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLI 353
                Y+ K Q+L  +  + +    E  ++G A+ FV  N F R         V +V V  
Sbjct: 1815 RWSDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYAGA---NVRRVAVFF 1871

Query: 354  SAGPSSDEIRYGVVALK------QASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRS 407
            S G ++         ++        +VF+F        R  L+    D+   F V     
Sbjct: 1872 SNGQTASRSSIITATMEFSALDISPTVFAFD------ERVFLEAFGFDNTGTFQVIPVPP 1925

Query: 408  FGDLQEKLLPYIVGVAQRHIVLKPPTIVTQVI--EVNKRDIVFLVDGSSALGLANFNAIR 465
             G+ Q   L  +   A  +    P   + +    E +  D+VFL+D S  +    F A++
Sbjct: 1926 NGENQT--LERLRRCALCYDKCFPNACIREAFLPEDSYMDVVFLIDNSRNIAKDEFKAVK 1983

Query: 466  DFIAKVIQRLEIGQDLI------QVAVAQYA---------DTVRPEFYFNTHPTKREVIT 510
              ++ VI    I  D +      ++A+  Y+          TV+ EF F T+  +  +  
Sbjct: 1984 ALVSSVIDNFNIASDPLISDSGDRIALLSYSPWESSRRKMGTVKTEFDFITYDNQLLMKN 2043

Query: 511  AVR-KMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDE---IS 566
             ++   + L+G A   G AL +   NLF  +   R      K++ +++ G++ +    + 
Sbjct: 2044 HIQTSFQQLNGEAT-IGRALLWTTENLFPETPYLRK----HKVIFVVSAGENYERKEFVK 2098

Query: 567  QPAQELKRSSIMAFAIGNKGADQAELEEIA 596
              A   K    + F I      + ++EE+A
Sbjct: 2099 MMALRAKCQGYVIFVISLGSTRKDDMEELA 2128



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 39/192 (20%), Positives = 87/192 (45%), Gaps = 23/192 (11%)

Query: 28   QQADVKNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSL------AVGENDFHFALV 81
            ++A +   +  D++FL+D+S  I ++ F+ V+  +  V+ +        + ++    AL+
Sbjct: 1952 REAFLPEDSYMDVVFLIDNSRNIAKDEFKAVKALVSSVIDNFNIASDPLISDSGDRIALL 2011

Query: 82   QFN---------GNPHTEFLLNTYRTKQEVLSHI-SNMSYIGGTNQTGKGLEYIMQSHLT 131
             ++         G   TEF   TY  +  + +HI ++   + G    G+ L +  ++   
Sbjct: 2012 SYSPWESSRRKMGTVKTEFDFITYDNQLLMKNHIQTSFQQLNGEATIGRALLWTTENLFP 2071

Query: 132  KAAGSRAGDGVPQVIVVLTDGHS---KDGLALPSAELKSADVNVFAIGVEDADEGALKEI 188
            +    R      +VI V++ G +   K+ + + +   K     +F I +    +  ++E+
Sbjct: 2072 ETPYLRK----HKVIFVVSAGENYERKEFVKMMALRAKCQGYVIFVISLGSTRKDDMEEL 2127

Query: 189  ASEPLNMHMFNL 200
            AS PL+ H+  L
Sbjct: 2128 ASYPLDQHLIQL 2139



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 41/180 (22%), Positives = 79/180 (43%), Gaps = 19/180 (10%)

Query: 39   DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDF------HFALVQFNG---NPHT 89
            D+ FL+D+S  +G + F+ V+ F+  V+    +             A++ ++     P+T
Sbjct: 2291 DVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPNT 2350

Query: 90   -------EFLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGV 142
                   EF L TY +  ++  H+ +   + G    G  L++ + +        R    +
Sbjct: 2351 EECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLRKNKVI 2410

Query: 143  PQVIVVLTDGHSKDGLALPS--AELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNL 200
              +    T+   KD L   S  A+ +   + VF+ G +  D+  L+E+AS PL+ H+  L
Sbjct: 2411 FVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHNDK-ELEELASHPLDHHLVQL 2469



 Score = 38.1 bits (87), Expect = 0.14
 Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 17/116 (14%)

Query: 1436 DIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKV------RVGVVQFSN------- 1482
            D+ FLID+S+ V  D F  ++ F++ ++   +I P+ +      RV V+ +S        
Sbjct: 2291 DVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPNT 2350

Query: 1483 ---DVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSR 1535
                V+ EF L TY S   +   ++  +   G  +  G AL++   N+FV +   R
Sbjct: 2351 EECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGD-VFIGHALQWTIDNVFVGTPNLR 2405


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score =  336 bits (862), Expect = 2e-91
 Identities = 267/837 (31%), Positives = 388/837 (46%), Gaps = 126/837 (15%)

Query: 1639 DIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFST 1698
            D+VFLLD S +  ++ F++V ++V+ +VDT     D  +VG+V+Y+  PT  F L  F +
Sbjct: 38   DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGS 97

Query: 1699 KRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSR-LDQRVPQIAFVITGGKSVE 1757
            + ++  A  ++ Y GG + NT   L ++    F P AG R  D+   Q+A ++T G+S +
Sbjct: 98   QEEVKAAARRLAYHGG-NTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQD 156

Query: 1758 DAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIAS--NSATAFRVGNVQELSELSEQVLET 1815
               D + A  + G+++FAVGV     EE+ +IAS   SA  F V +   + ++  ++   
Sbjct: 157  LVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRGKLRRR 216

Query: 1816 LHDAMHETLCPGVT---DAAKACNLDVILGFDGSRDQNVFVAQKGFESKVDAILNRISQM 1872
            L       LCP V    D  K  N        G+++   F     F   V  IL +    
Sbjct: 217  L---CENVLCPSVRVEGDRFKHTN-------GGTKEITGFDLMDLF--SVKEILGKRE-- 262

Query: 1873 HRVSCSGGRSPTVRVS---VVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQHPYVLTE-- 1927
                 +G +S  VR+    VV +T     +    DEY      +FR    +  + + +  
Sbjct: 263  -----NGAQSSYVRMGSFPVVQSTEDVFPQGLP-DEYAFVTTFRFRKTSRKEDWYIWQVI 316

Query: 1928 DTLKVYLNKFR-------------QSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGV 1974
            D   +     R              +  D+V+VV   +   D    D H+ + +++ + V
Sbjct: 317  DQYSIPQVSIRLDGENKAVEYNAVGAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNV 376

Query: 1975 RALILVGLERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQL----DNIAE-KAC 2029
               I   L + + +E   +++     +  + L  + + +D++L   +       AE + C
Sbjct: 377  SLHIDCALVQTLPIEERENIDIQGKTVIGKRL-YDSVPIDFDLQRIVIYCDSRHAELETC 435

Query: 2030 CGV---PCKC-------------------SGQRGDRGPIGSIGPKGIPGEDGY---RGYP 2064
            C +   PC+                    S Q G    I    P G  GE G     G P
Sbjct: 436  CDIPSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLP 495

Query: 2065 GDEG----------------------GPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGE 2102
            G +G                      GP  +G  G  G+ G  G PG+ G KG RG PGE
Sbjct: 496  GPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGE 555

Query: 2103 KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQ 2162
             GE G  G  G+ G  G  GLPG  G  G PG +G++G +G +GE+G+ G+ G PG PG 
Sbjct: 556  LGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGD 615

Query: 2163 DSQE--------RGPKGETGDLGPMGVPG-------RDGVPGGPGETGKNGGFGRRGPPG 2207
              Q+         GP+GE GD+GP G PG       ++G+ G  G  G  G  G  GPPG
Sbjct: 616  TGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPG 675

Query: 2208 AKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQ------GISGPRGSGGAAGAPG 2261
            A+G  G  G+ G  G QG RG +G  GP G PGL+G Q      G+ GP G GG+ G PG
Sbjct: 676  ARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPG 735

Query: 2262 E---RGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPG 2317
            E    G+ GP G  G PG+ GP G  G  G +GE G+ G DG+ G  G RG+ GE+G  G
Sbjct: 736  EIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAG 795

Query: 2318 YPGPKGN---PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
             PG KG    PG PG  G  G KG +G +G  G PG+ G +G+ G  GPAGP G  G
Sbjct: 796  RPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPG 852



 Score =  275 bits (704), Expect = 4e-73
 Identities = 158/365 (43%), Positives = 193/365 (52%), Gaps = 27/365 (7%)

Query: 2030 CGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEG-------GPGERGPPGVNGTQ 2082
            C  P    G+ G  GP+G  GPKG  G  G  G PG +G       GP  +G  G  G+ 
Sbjct: 476  CSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSL 535

Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142
            G  G PG+ G KG RG PGE GE G  G  G+ G  G  GLPG  G  G PG +G++G +
Sbjct: 536  GLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEK 595

Query: 2143 GEKGERGDVGIRGDPGNPGQDSQE--------RGPKGETGDLGPMGVPG-------RDGV 2187
            G +GE+G+ G+ G PG PG   Q+         GP+GE GD+GP G PG       ++G+
Sbjct: 596  GTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGL 655

Query: 2188 PGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGI 2247
             G  G  G  G  G  GPPGA+G  G  G+ G  G QG RG +G  GP G PGL+G QG 
Sbjct: 656  KGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGP 715

Query: 2248 SGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRR 2307
             GP G  G  G  G  G  G +G  G+PG PGP G  G  GP G  G  G     ++G  
Sbjct: 716  PGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPG-----TKGEP 770

Query: 2308 GKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPK 2367
            G++GE G PG PG +G  GE GL G  G KG  G  G  G PG+ G+KGD G  G  G  
Sbjct: 771  GERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLP 830

Query: 2368 GNRGD 2372
            G +GD
Sbjct: 831  GLKGD 835



 Score =  270 bits (689), Expect = 2e-71
 Identities = 173/418 (41%), Positives = 208/418 (49%), Gaps = 69/418 (16%)

Query: 2024 IAEKACCGVP-----CKCSGQ--RGDRGPIGSIGPKGIPGEDGY--RGYPGDEGGPGERG 2074
            +  KA CG       C   GQ  +GDRG  G  G  G  G+ G    G PG  G PG++G
Sbjct: 1001 LGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKG 1060

Query: 2075 PPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGL------------------DG 2116
             PG  G  GF G  G  G  G+ G PGE+G  G+ GL  L                   G
Sbjct: 1061 SPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPG 1120

Query: 2117 EDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPG-QDSQ-ERGPKGETG 2174
              G  GLPG  G+KG PG+ G +G  G+KGE G  G+ G PG  G Q SQ ERG  GE G
Sbjct: 1121 PPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVG 1180

Query: 2175 ---DLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKG--------GP-GQPGFEG 2222
               D G  GVPG  G PG PG  G +G  G  GPPG +G+ G        GP G PG  G
Sbjct: 1181 QKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPG 1240

Query: 2223 EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGA---------AGAPGERGRTGPLGRKG 2273
            E+G  G  G  GP G PG  GE G+ GP G+ G          +GAPG RG +G +G  G
Sbjct: 1241 EEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPG 1300

Query: 2274 EPGEPG---------PKGGIGNRGPRGETGDDGRDGV----GSEGRRGKKGERGFPGYPG 2320
            + G PG         P+G  G RGP G+ G  G  G     G+ G++G KGE G PG PG
Sbjct: 1301 QEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPG 1360

Query: 2321 ---PKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSID 2375
               P+G PGEPG  G  G +G+ G+ G    PG  G++GDPG  G  GP G +G   D
Sbjct: 1361 FLGPRGPPGEPGEKGVPGKEGVPGKPGE---PGFKGERGDPGIKGDKGPPGGKGQPGD 1415



 Score =  267 bits (682), Expect = 1e-70
 Identities = 166/375 (44%), Positives = 196/375 (52%), Gaps = 51/375 (13%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGG---PGERGPPGVNGTQGFQGCPGQRGVK 2094
            G  G  GP G  G  G+PGE G+ G PG  G    PG+ GP G  G  G +G PG+RG  
Sbjct: 717  GPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGED 776

Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGE---------K 2145
            G  G PG +GE+GE GL G  GE G+ GLPG+ G  G  G +GD+G +GE         +
Sbjct: 777  GLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDR 836

Query: 2146 GERGDVGIRGDPGNPGQDSQ---------ERGPKGETGDLGPMGVPGRDGVPGGPGETGK 2196
            GE+G+ G  G PG PG  S          E+GPKGE GD    G+PG  G+ G PGE G 
Sbjct: 837  GEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGD---PGLPGEPGLQGRPGELGP 893

Query: 2197 NGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGI------SGP 2250
             G     GPPGAKG +G  G PG  G  G  G  G  GP+GPPG +G  G+       G 
Sbjct: 894  QGP---TGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGE 950

Query: 2251 RGSGGAAGAPGERGRTGPLGRKGEPGEPGP--KGGIGNRGPRGETGDDGRDGV------- 2301
            RG  GAAG  G  G  GP G  G PG PGP  KG  G  G RG  G  G  G        
Sbjct: 951  RGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKV 1010

Query: 2302 -GSE----GRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKG 2356
             GSE    G +  KG+RG PG PG  G+ G+PG+ G  GP G  G  G+ G P   G +G
Sbjct: 1011 RGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSGPPGDKGSP---GSRG 1066

Query: 2357 DPGYPGPAGPKGNRG 2371
             PG+PGP GP G  G
Sbjct: 1067 LPGFPGPQGPAGRDG 1081



 Score =  256 bits (654), Expect = 2e-67
 Identities = 162/392 (41%), Positives = 191/392 (48%), Gaps = 61/392 (15%)

Query: 2038 GQRGDRG------PIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGT-------QGF 2084
            G++G+RG        G  G +G PG  G  G  G++G  G  GPPGV G+       +G 
Sbjct: 599  GEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGE 658

Query: 2085 QGCPGQRGVKGSRGFPGEKGEVGEIGLDG------LDGEDGDKGLPGS------SGEKGN 2132
            QG PG RG +G+ G PG +G +G  G DG      L G+ GD G PG        G  G 
Sbjct: 659  QGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGP 718

Query: 2133 PGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPG--------- 2183
            PG  G  GP G  G  G++G  G PG PG      GP G+ G  GP G PG         
Sbjct: 719  PGVPGPPGPGGSPGLPGEIGFPGKPGPPGPT----GPPGKDGPNGPPGPPGTKGEPGERG 774

Query: 2184 RDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIG 2243
             DG+PG PG  G+ G  G  G PG KG  G PG PGF G +G +G QG  G  G PGL G
Sbjct: 775  EDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKG 834

Query: 2244 EQGISGPRGSGGAAGAPGER----------GRTGPLGRKGEPG---EPGPKGGIGNRGPR 2290
            ++G  G  G  G  G PG            G  GP G KG+PG   EPG +G  G  GP+
Sbjct: 835  DRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQ 894

Query: 2291 GETGDDGRDGV-------GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRR 2343
            G TG  G  G        G+ G  G  G  G PG  GP G+ G PGL GT G  G RG +
Sbjct: 895  GPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEK 954

Query: 2344 G---NSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
            G     G PG VG +GDPG PG  GP G   D
Sbjct: 955  GAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKD 986



 Score =  254 bits (648), Expect = 1e-66
 Identities = 169/419 (40%), Positives = 198/419 (47%), Gaps = 69/419 (16%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQ-------------- 2082
            SG  GD+G  GS G  G PG  G  G  G  G PGERGPPG  G                
Sbjct: 1053 SGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKD 1112

Query: 2083 -------GFQGCPGQRGVKGSRGFPGE------KGEVGEIGLDGLDGEDGDKGLPGSSGE 2129
                   G  G PG  G KG +G PG+      +G+ GE G  GL G  G  G  GS GE
Sbjct: 1113 VCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGE 1172

Query: 2130 KGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQD-----SQERGPKGETGDLGPMGVPGR 2184
            +G  G  G KG +G  G  G +G  G+PG PG D     +   G +G  G  GP G  G 
Sbjct: 1173 RGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGP 1232

Query: 2185 DGVPGGPGETGKNGGFGRRGPPGAKGNKGGPG---------QPGFEGEQGTRGAQGPAGP 2235
             G+PG PGE GK G  G+ GPPG  G  G PG          PGF+G  G  GA GP G 
Sbjct: 1233 SGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGE 1292

Query: 2236 AGPPGLIGEQGI---------------SGPRGSGGAAGAPGERGRTGPLGR------KGE 2274
            +G  GL G++G+                GPRG  G  G+PG  G  GP G       KGE
Sbjct: 1293 SGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGE 1352

Query: 2275 PGEPGPKGGIGNRGPRGETGDDG---RDGV-GSEGRRGKKGERGFPGYPG---PKGNPGE 2327
             G PG  G +G RGP GE G+ G   ++GV G  G  G KGERG PG  G   P G  G+
Sbjct: 1353 NGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQ 1412

Query: 2328 PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDK 2386
            PG  G  G KG  G  G  G PG  G  G PG PG  G  G RG+S     L + I+++
Sbjct: 1413 PGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEE 1471



 Score =  253 bits (645), Expect = 3e-66
 Identities = 173/453 (38%), Positives = 206/453 (45%), Gaps = 77/453 (16%)

Query: 2031 GVPCK-----CSGQRGDRGPIGSIGPKGIPG---EDGYRGYPGDEGGPGERGPPGVNGTQ 2082
            GVP K       G++G+ GP G  GP GI G     G RG  G+ G  G++G PGV G  
Sbjct: 1135 GVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFM 1194

Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142
            G  G PG  G  G  G  G  G  G  G +G  G  G  GLPG  GE+G  GR G  GP 
Sbjct: 1195 GPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPP 1254

Query: 2143 GEKGERGDVGI------RGDPGNPGQ--DSQERGPKGETGDLGPMGVPGRDGVPGGPGET 2194
            GE G+ G+ G+      RG PG  G   DS   GP+GE+G    MG+PG++G+PG  G+T
Sbjct: 1255 GEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESG---AMGLPGQEGLPGKDGDT 1311

Query: 2195 GKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSG 2254
            G  G  G +GP G  G  G PG PG  G  GT G +G  G  G PGL G  G  GP G  
Sbjct: 1312 GPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEP 1371

Query: 2255 GAAGAPGERG---RTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG----VGSEGRR 2307
            G  G PG+ G   + G  G KGE G+PG KG  G  G +G+ GD G  G     G  G +
Sbjct: 1372 GEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQ 1431

Query: 2308 GKKGERGFPGYPGPKGNPGEPGLNGTT--------------------------------- 2334
            G  GE G  G PGP G PG PGL G +                                 
Sbjct: 1432 GLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAY 1491

Query: 2335 --------------GPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALI 2380
                          G  G+ GR G  G PG  GQ G  G  GP GPKG RG   D  A  
Sbjct: 1492 MKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG 1551

Query: 2381 QSIKDKCPCCYGPLECPVFPTELAFALDTSEGV 2413
              ++ +     GP   P  P E  +A D   G+
Sbjct: 1552 VGLRGE----MGPPGIPGQPGEPGYAKDGLPGI 1580



 Score =  252 bits (644), Expect = 4e-66
 Identities = 154/358 (43%), Positives = 181/358 (50%), Gaps = 23/358 (6%)

Query: 2024 IAEKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQG 2083
            +A+  C   P    G  G  G  G  G  G PG +G  G  G+ G PG  GPPG+ G QG
Sbjct: 1109 LAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQG 1168

Query: 2084 FQ---GCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKG 2140
             Q   G  G+ G KG +G PG  G +G  G  G  G DG  G  G  G +G+PG+ G  G
Sbjct: 1169 SQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPG 1228

Query: 2141 PRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGF 2200
            P+G  G     GI G+ G  G+D +  GP GE G  G  G+PG +G  G PG  G  G  
Sbjct: 1229 PQGPSGL---PGIPGEEGKEGRDGKP-GPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDS 1284

Query: 2201 GRRGPPGAKGNKGGPGQ---PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAA 2257
            G  GP G  G  G PGQ   PG +G+ G  G QGP GP GPP         G  GS G+ 
Sbjct: 1285 GAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPP---------GKNGSPGSP 1335

Query: 2258 GAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGD---DGRDGV-GSEGRRGKKGER 2313
            G PG  G  G  G KGE G PG  G +G RGP GE G+    G++GV G  G  G KGER
Sbjct: 1336 GEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGER 1395

Query: 2314 GFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
            G PG  G KG PG  G  G  G  G +G  G  GP G+ G+ G  G PGP G  G  G
Sbjct: 1396 GDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPG 1453



 Score =  250 bits (639), Expect = 1e-65
 Identities = 167/427 (39%), Positives = 196/427 (45%), Gaps = 93/427 (21%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGY---PGDEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094
            G+ G  GP G  G  GIPGE+G  G    PG  G PG+ G PG+ G +G +G PG +G  
Sbjct: 1222 GKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHT 1281

Query: 2095 GSRGFPGEKGEVGEIGL---DGLDGEDGDKGLPGSSG---------EKGNPGRRGDKGPR 2142
            G  G PG +GE G +GL   +GL G+DGD G  G  G         + G+PG  G+ GP 
Sbjct: 1282 GDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPS 1341

Query: 2143 GEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGR 2202
            G  G++G  G  G PG PG      GP+G  G+ G  GVPG++GVPG PGE G  G  G 
Sbjct: 1342 GTPGQKGSKGENGSPGLPGF----LGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGD 1397

Query: 2203 ------RGPPGAKGNKGGPGQPGFEGEQGTRGAQG------PAGPAGPPGLIG------- 2243
                  +GPPG KG  G PG PG +G  G  G QG      P GP GPPG  G       
Sbjct: 1398 PGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGE 1457

Query: 2244 -------------------------------------EQGISGPRGSGGAAGAPGERGRT 2266
                                                  QG  GP G  G  G PG  G  
Sbjct: 1458 SPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPM 1517

Query: 2267 GPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPG 2326
            G  GR G+ G  GP G IG +G RG  GD G  GV      G +GE G PG P   G PG
Sbjct: 1518 GEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGV------GLRGEMGPPGIP---GQPG 1568

Query: 2327 EPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDK 2386
            EPG     G  GI G +G +GP       G PG PGP GP G    S  QCA   S+  +
Sbjct: 1569 EPGY-AKDGLPGIPGPQGETGP------AGHPGLPGPPGPPGQCDPS--QCAYFASLAAR 1619

Query: 2387 CPCCYGP 2393
                 GP
Sbjct: 1620 PGNVKGP 1626



 Score =  250 bits (638), Expect = 2e-65
 Identities = 166/441 (37%), Positives = 196/441 (44%), Gaps = 94/441 (21%)

Query: 2026 EKACCGVPCK--CSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGE---------RG 2074
            EK   G+P +    G+ G+ GP G  GP G  G++G  G PG  G PG           G
Sbjct: 872  EKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSG 931

Query: 2075 PPGVNGTQGFQGCPG---QRGVKGS---RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSG 2128
            PPG  G  G +G PG   +RG KG+    G PG  G  G+ G  GL G  G KG  G  G
Sbjct: 932  PPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPG 990

Query: 2129 EKGNPGRRGD-----------------------KGPRGEKGERGDVGIRGDPG------- 2158
             +G+PG  G                        KG RG  G  G  G RGDPG       
Sbjct: 991  LRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPP 1050

Query: 2159 ---NPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNG--GF------------- 2200
                P  D    G +G  G  GP G  GRDG PG PGE G  G  G              
Sbjct: 1051 GPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLA 1110

Query: 2201 ------------GRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGIS 2248
                        G  G PG KG+KG PG+PG EG +G +G  GP G  GPPG+ G QG  
Sbjct: 1111 KDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQ 1170

Query: 2249 GPRGSGGAAGAPGERGRTGPLGRKGEPGEPGP---------------KGGIGNRGPRGET 2293
            G RG+ G  G  G++G  G  G  G PG PGP               +G  G  GP G  
Sbjct: 1171 GERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQ 1230

Query: 2294 GDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIV 2352
            G  G  G+ G EG+ G+ G+ G PG PG  G PG PG  G  GP G +G  G+SG PG  
Sbjct: 1231 GPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPR 1290

Query: 2353 GQKGDPGYPGPAGPKGNRGDS 2373
            G+ G  G PG  G  G  GD+
Sbjct: 1291 GESGAMGLPGQEGLPGKDGDT 1311



 Score =  248 bits (632), Expect = 9e-65
 Identities = 158/427 (37%), Positives = 201/427 (47%), Gaps = 92/427 (21%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGE------RGPPGVNGTQGFQG 2086
            P    G+RG  G +G  G +G PG  G+ G PG+ G PG        GPPG+ G+ G +G
Sbjct: 1166 PQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEG 1225

Query: 2087 CPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDG---DKGLPGSSGEKGNPGRRG---DKG 2140
             PG +G  G  G PGE+G+ G  G  G  GE G   + GLPG  G +G PG +G   D G
Sbjct: 1226 PPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSG 1285

Query: 2141 PRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGF 2200
              G +GE G +G+ G  G PG+D  + GP G  G  GP G PG++G PG PGE G +G  
Sbjct: 1286 APGPRGESGAMGLPGQEGLPGKDG-DTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTP 1344

Query: 2201 GRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAP 2260
            G++G   +KG  G PG PGF G +G  G  G  G  G  G+ G+ G  G +G  G  G  
Sbjct: 1345 GQKG---SKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIK 1401

Query: 2261 GERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-------GSEGRRGK---- 2309
            G++G  G  G+ G+PG PG KG  G  GP+G  G++G  G        G  G RG+    
Sbjct: 1402 GDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSM 1461

Query: 2310 -------------------------------KGERGFPGYPGP---------------KG 2323
                                           K  +G PG PGP                G
Sbjct: 1462 ETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPG 1521

Query: 2324 NPGEPGLNGTTGPKGIRGR--------------RGNSGPPGIVGQKGDPGY-----PGPA 2364
             PG+ GL G +GP G +G               RG  GPPGI GQ G+PGY     PG  
Sbjct: 1522 RPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIP 1581

Query: 2365 GPKGNRG 2371
            GP+G  G
Sbjct: 1582 GPQGETG 1588



 Score =  239 bits (611), Expect = 2e-62
 Identities = 157/395 (39%), Positives = 182/395 (46%), Gaps = 62/395 (15%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGD--EGGPGERGPPGVNG----------TQGFQ 2085
            G  G+ G  G +GP+G PG  G  G PG   +G PG RG PG+ G           +G +
Sbjct: 955  GAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSE 1014

Query: 2086 GCP-------GQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGD 2138
             C        G RG  G  G PG +G+ G IG+ G  G  G  G  GS G +G PG  G 
Sbjct: 1015 NCALGGQCVKGDRGAPGIPGSPGSRGDPG-IGVAGPPGPSGPPGDKGSPGSRGLPGFPGP 1073

Query: 2139 KGPRGEKGERGDVGIRGDPGNPG--------------QDSQERGPKGETGDLGPMGVPGR 2184
            +GP G  G  G+ G RG PG PG              +D     P G  G  G  G  G 
Sbjct: 1074 QGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGD 1133

Query: 2185 DGVPGGPGETGKNGGFGRRGPPGAKGNKG--GP-------------GQPGFEGEQGTRGA 2229
             GVPG PG  G  G  G  GPPG  G  G  GP             GQ G +G  G  G 
Sbjct: 1134 KGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGF 1193

Query: 2230 QGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGP 2289
             GP G  GPPG  G  G +GP G  G+ G  G  G  GP G  G PGE G +G  G  GP
Sbjct: 1194 MGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGP 1253

Query: 2290 RGETGDDGRDGV-GSEGRRGK---KGERGFPGYPGPKGNPGE---------PGLNGTTGP 2336
             GE G  G  G+ G EG RG    KG  G  G PGP+G  G          PG +G TGP
Sbjct: 1254 PGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGP 1313

Query: 2337 KGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
             G +G +G  GPPG  G  G PG PGP+G  G +G
Sbjct: 1314 TGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKG 1348



 Score =  129 bits (324), Expect = 5e-29
 Identities = 90/254 (35%), Positives = 138/254 (54%), Gaps = 29/254 (11%)

Query: 628 SGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTP 687
           +G   VH    D++FLLD S++VGK +F  VR +V NLV++ ++G D  RVG+V++SD P
Sbjct: 30  AGCKSVHY---DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRP 86

Query: 688 VTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHV-PQL 746
            T F L  + ++ ++    R+L   GG+  NTG AL Y+ A  F+   G R R+    Q+
Sbjct: 87  TTAFELGLFGSQEEVKAAARRLAYHGGN-TNTGDALRYITARSFSPHAGGRPRDRAYKQV 145

Query: 747 LLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNP--SLVYLMDDFSS 804
            +LLT G+S+D  L AA A  RAGI  F VG  +A K ELE+IA  P  + V+ + DF++
Sbjct: 146 AILLTDGRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNA 205

Query: 805 LPALPQQLIQPLT---------------TYVSGGVEEV---PLAQPESKRDILFLFDGSA 846
           +  +  +L + L                 + +GG +E+    L    S ++IL   +  A
Sbjct: 206 IDKIRGKLRRRLCENVLCPSVRVEGDRFKHTNGGTKEITGFDLMDLFSVKEILGKRENGA 265

Query: 847 N----LVGQFPVVR 856
                 +G FPVV+
Sbjct: 266 QSSYVRMGSFPVVQ 279



 Score =  115 bits (288), Expect = 7e-25
 Identities = 74/227 (32%), Positives = 124/227 (54%), Gaps = 10/227 (4%)

Query: 26  QQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNG 85
           Q Q+A  K+    D++FL+D+S ++G+E F+ VR+++ ++V +  VG +     +V+++ 
Sbjct: 26  QAQRAGCKS-VHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSD 84

Query: 86  NPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGD-GVPQ 144
            P T F L  + +++EV +    ++Y GG   TG  L YI     +  AG R  D    Q
Sbjct: 85  RPTTAFELGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQ 144

Query: 145 VIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFT 204
           V ++LTDG S+D +   +A    A + +FA+GV +A +  L+EIASEP + H+F++ +F 
Sbjct: 145 VAILLTDGRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFN 204

Query: 205 SLHDIVGNL-------VSCVHSSVSPERAGDTE-TLKDITAQDSADI 243
           ++  I G L       V C    V  +R   T    K+IT  D  D+
Sbjct: 205 AIDKIRGKLRRRLCENVLCPSVRVEGDRFKHTNGGTKEITGFDLMDL 251



 Score = 99.8 bits (247), Expect = 4e-20
 Identities = 71/183 (38%), Positives = 82/183 (44%), Gaps = 42/183 (22%)

Query: 2232 PAGPAGPP-------GLIGEQGISGPRGSGGAAGAPGERGRTGP---LGRKGEPGEPGPK 2281
            P  P  PP       G +     S P G  G  G  G  G  GP   +G  G  G PGPK
Sbjct: 454  PPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPK 513

Query: 2282 G-----GIG--NRGPRGETGDDGRDGV----GSEGRRGKKGE---------------RGF 2315
            G     GIG   +G +GE G  G  G     GS+G RG+ GE               +G 
Sbjct: 514  GEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGP 573

Query: 2316 PGYPGPKGNPGEPGLNGTTGPKGIRGRRGN------SGPPGIVGQKGDPGYPGPAGPKGN 2369
            PG PGP G  G PGL G  G KG RG +G        G PG  GQ+G PG  G AGP+G 
Sbjct: 574  PGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGE 633

Query: 2370 RGD 2372
            +GD
Sbjct: 634  KGD 636



 Score = 99.4 bits (246), Expect = 5e-20
 Identities = 89/266 (33%), Positives = 129/266 (48%), Gaps = 27/266 (10%)

Query: 1233 DVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSS 1291
            D+VFL+D S S G E F+ VR  +  LVD  +VG D TRV V+++SD P   F L    S
Sbjct: 38   DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGS 97

Query: 1292 KDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSR-IEEGVPQFLVLISSGKSDD 1350
            ++EV+ A +RL   GG   N G+AL Y++   F    G R  +    Q  +L++ G+S D
Sbjct: 98   QEEVKAAARRLAYHGG-NTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQD 156

Query: 1351 EVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSPE--YVFSVSTFRELPSLEQKLLTP 1407
             V D A    + G+  F +    A +EEL +I+  P+  +VF VS F  +  +  KL   
Sbjct: 157  LVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRGKLR-- 214

Query: 1408 ITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDF-VSRIVRRL 1466
                     ++L  +   P   VE D     F   +       GF  +  F V  I+ + 
Sbjct: 215  ---------RRLCENVLCPSVRVEGDR----FKHTNGGTKEITGFDLMDLFSVKEILGKR 261

Query: 1467 NIG--PSKVRVG---VVQFSNDVFPE 1487
              G   S VR+G   VVQ + DVFP+
Sbjct: 262  ENGAQSSYVRMGSFPVVQSTEDVFPQ 287



 Score = 95.1 bits (235), Expect = 1e-18
 Identities = 55/177 (31%), Positives = 95/177 (53%), Gaps = 4/177 (2%)

Query: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 301
           D++FL+D S++ G  +F  +  ++ NL++   +G  + RVGVV++SD P T F L  + +
Sbjct: 38  DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGS 97

Query: 302 KAQVLGAVKALGFAGGELANIGLALDFVVENHFT-RAGGSRVEEGVPQVLVLISAGPSSD 360
           + +V  A + L + GG   N G AL ++    F+  AGG   +    QV +L++ G S D
Sbjct: 98  QEEVKAAARRLAYHGGN-TNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQD 156

Query: 361 EIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNL--VFTVPEFRSFGDLQEKL 415
            +     A  +A +  F +G   A + EL+ IA++     VF V +F +   ++ KL
Sbjct: 157 LVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRGKL 213



 Score = 93.2 bits (230), Expect = 4e-18
 Identities = 62/189 (32%), Positives = 94/189 (49%), Gaps = 4/189 (2%)

Query: 1436 DIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRS 1495
            D+VFL+D+S  V  + F  +R +V+ +V    +GP + RVGVV++S+     F L  + S
Sbjct: 38   DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGS 97

Query: 1496 QAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIED-GVPQHLVLVLGGKSQD 1554
            Q  V  A RRL   GG+  NTG AL ++    F   AG R  D    Q  +L+  G+SQD
Sbjct: 98   QEEVKAAARRLAYHGGN-TNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQD 156

Query: 1555 DVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRL--VFTVREFRELPNIEERIMNS 1612
             V   A     +GI    VG     + EL+ I ++P+   VF V +F  +  I  ++   
Sbjct: 157  LVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRGKLRRR 216

Query: 1613 FGPSAATPA 1621
               +   P+
Sbjct: 217  LCENVLCPS 225



 Score = 86.3 bits (212), Expect = 4e-16
 Identities = 64/180 (35%), Positives = 94/180 (52%), Gaps = 7/180 (3%)

Query: 1012 LLKSVHNGAPAPVSGEK----DVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVR 1066
            LL S   G  A  +G K    D+VFLLD S  V +  F  ++++V  +V++ +VG DR R
Sbjct: 17   LLWSGGGGCQAQRAGCKSVHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTR 76

Query: 1067 VAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGS 1126
            V VV+YSDR    F L  + ++++V  A R+L   GG T NTG AL ++        AG 
Sbjct: 77   VGVVRYSDRPTTAFELGLFGSQEEVKAAARRLAYHGGNT-NTGDALRYITARSFSPHAGG 135

Query: 1127 RITE-GVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFA 1185
            R  +    Q+ I+LT  RS D V + +    R G     +G+G A   E++ I+  P  A
Sbjct: 136  RPRDRAYKQVAILLTDGRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSA 195



 Score = 85.1 bits (209), Expect = 1e-15
 Identities = 62/201 (30%), Positives = 102/201 (50%), Gaps = 10/201 (4%)

Query: 445 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 504
           D+VFL+D SS++G  +F  +R ++A ++   E+G D  +V V +Y+D     F      +
Sbjct: 38  DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGS 97

Query: 505 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAE-GIPKLLVLITGGKSLD 563
           + EV  A R++    G    TG AL ++    F+  AG R  +    ++ +L+T G+S D
Sbjct: 98  QEEVKAAARRL-AYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQD 156

Query: 564 EISQPAQELKRSSIMAFAIGNKGADQAELEEIAFD--SSLVFIPAEFRAA-PLQGML--- 617
            +   A    R+ I  FA+G   A + ELEEIA +  S+ VF  ++F A   ++G L   
Sbjct: 157 LVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRGKLRRR 216

Query: 618 --PGLLAPLRTLSGTPEVHSN 636
               +L P   + G    H+N
Sbjct: 217 LCENVLCPSVRVEGDRFKHTN 237



 Score = 61.6 bits (148), Expect = 1e-08
 Identities = 48/156 (30%), Positives = 71/156 (45%), Gaps = 3/156 (1%)

Query: 837 DILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQS 895
           D++FL D S+++  + F  VR ++  ++D   V P+ TR+ V +YSD            S
Sbjct: 38  DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGS 97

Query: 896 KPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIED-GVLQFLVLLVAGRSSD 954
           + E+    +R+    G   N G AL Y     F   AG R  D    Q  +LL  GRS D
Sbjct: 98  QEEVKAAARRLAYHGGNT-NTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQD 156

Query: 955 RVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSP 990
            V   A+   ++G+  F      A   ELE+I   P
Sbjct: 157 LVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEP 192



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 48/202 (23%), Positives = 84/202 (41%), Gaps = 31/202 (15%)

Query: 2609 RRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQ 2668
            +RA    V  D+ F+LD++ +     F ++++++A LV   ++ PD        RV VV+
Sbjct: 28   QRAGCKSVHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDR------TRVGVVR 81

Query: 2669 HAPSESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFE 2728
            ++   +            F L  +GS+E+ V   +R +    G    G A+ Y     F 
Sbjct: 82   YSDRPT----------TAFELGLFGSQEE-VKAAARRLAYHGGNTNTGDALRYITARSFS 130

Query: 2729 ----SAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVY 2784
                  P  R  K V ++LT    +  + +A     +A   G     +G+G  +  +E+ 
Sbjct: 131  PHAGGRPRDRAYKQVAILLTDGRSQDLVLDAAAAAHRA---GIRIFAVGVGEALK-EELE 186

Query: 2785 TFASEPNDVF------FKLVDK 2800
              ASEP          F  +DK
Sbjct: 187  EIASEPKSAHVFHVSDFNAIDK 208


>gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]
          Length = 1028

 Score =  335 bits (859), Expect = 4e-91
 Identities = 252/790 (31%), Positives = 359/790 (45%), Gaps = 72/790 (9%)

Query: 2017 LAEQLDNIAEKACCGVPCK-CSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGP 2075
            + + + N  E+ CC   C+   G  G RG  G  G +G PG  G +G  GD G PG+ GP
Sbjct: 235  IVDMIKNNVEQVCCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP 294

Query: 2076 PGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGR 2135
             G    QG +G  G RG KGSRG  G KGE G+ G+DG+DG  G+ G PG  G KG+PG 
Sbjct: 295  VGY---QGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGF 351

Query: 2136 RGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETG 2195
             G +GP G KG+ G  G++G+ G PG D    G  G  G  GP G  G+ G PG PGE G
Sbjct: 352  DGIQGPPGPKGDPGAFGLKGEKGEPGAD----GEAGRPGSSGPSGDEGQPGEPGPPGEKG 407

Query: 2196 KNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGG 2255
            + G  G  GP GA G +GGPG      E+G RG  G  GP G PG  G QG  G  G  G
Sbjct: 408  EAGDEGNPGPDGAPGERGGPG------ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVG 461

Query: 2256 AAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGF 2315
              G PGE G  GP G +G+ G PG +G  G  GP G  GD G  G   E      G  GF
Sbjct: 462  VPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGF 521

Query: 2316 PGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPP----------GIVGQKGDPGYPGPAG 2365
            PG+PG  GN G PG+NGT G  G++G  G +G P          G+ G KG  G  GP G
Sbjct: 522  PGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQG 581

Query: 2366 PKGNRG-DSIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVNQDTFGRMRDV 2424
            P G++G    D+C ++  I   C CC    EC   P +L F LD+SE +    F   +D 
Sbjct: 582  PPGHQGPPGPDECEILDIIMKMCSCC----ECKCGPIDLLFVLDSSESIGLQNFEIAKDF 637

Query: 2425 VLSIVNDLTIAE--SNCPRGARVAVVTYNNEVTTE---IRFADSKRKSVLLDKIKNLQVA 2479
            V+ +++ L+  E     P  +   VV Y++    E   +R    +    L + IK+LQ  
Sbjct: 638  VVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQ-- 695

Query: 2480 LTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTRASP--QLREAVLKLSDAG 2537
              +       A+ +          N  +   +    S+T    +P   L    +++   G
Sbjct: 696  WMAGGTFTGEALQYTRDQLLPPSPNNRIALVITDGRSDTQRDTTPLNVLCSPGIQVVSVG 755

Query: 2538 ITPLFLTRQEDRQL----INALQINNTAVGHALVLPAGRDLTD--FLENVLTCHVCLDIC 2591
            I  +F       QL       L  +    G +LV     +L +  FL+NV T  +C+D  
Sbjct: 756  IKDVFDFIPGSDQLNVISCQGLAPSQGRPGLSLVKENYAELLEDAFLKNV-TAQICIDKK 814

Query: 2592 NIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDM 2651
              D +C      P+             D+  +LD + +     F+  K++   L  +  +
Sbjct: 815  CPDYTCPITFSSPA-------------DITILLDGSASVGSHNFDTTKRFAKRLAERF-L 860

Query: 2652 SPDPKASQHFARVAVVQHAPS--ESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQL 2709
            +       H  RVAVVQ++ +  +  + AS+        L +Y +    VD     M  +
Sbjct: 861  TAGRTDPAHDVRVAVVQYSGTGQQRPERASLQ------FLQNYTALASAVD----AMDFI 910

Query: 2710 QGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFF 2769
                 +  A+ Y +   +  A +    K ++L   G          ++ + +A+  G   
Sbjct: 911  NDATDVNDALGY-VTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQEAQRAGIEI 969

Query: 2770 VVLGIGRKVN 2779
             V+ +GR+VN
Sbjct: 970  FVVVVGRQVN 979



 Score = 71.6 bits (174), Expect = 1e-11
 Identities = 97/372 (26%), Positives = 141/372 (37%), Gaps = 54/372 (14%)

Query: 445 DIVFLVDGSSALGLANFNAIRDFIAKVIQRL--------EIGQDLIQVAVAQYADTVRPE 496
           D++F++D S ++GL NF   +DF+ KVI RL        E GQ      V QY+ +   E
Sbjct: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQS--YAGVVQYSHSQMQE 672

Query: 497 FYFNTHPTKREVITAVRKMKPLDGSA--LYTGSALDFVRNNLFTSSAGYRAAEGIPKLLV 554
                 P+ R V      +K L   A   +TG AL + R+ L   S   R A      LV
Sbjct: 673 HVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNRIA------LV 726

Query: 555 LITGGKSLDEISQPAQELKRSSIMAFAIGNK-------GADQAE------LEEIAFDSSL 601
           +  G       + P   L    I   ++G K       G+DQ        L        L
Sbjct: 727 ITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGL 786

Query: 602 VFIPAEFRAAPLQGMLPGLLAPLRTLSGTPE-----VHSNKRDIIFLLDGSANVGKTNFP 656
             +   +        L  + A +      P+       S+  DI  LLDGSA+VG  NF 
Sbjct: 787 SLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHNFD 846

Query: 657 YVRDFVMNLVNS-LDIGN----DNIRVGLVQFSDT---PVTEFSLNTYQTKSDILGHLRQ 708
             + F   L    L  G      ++RV +VQ+S T        SL   Q  + +   +  
Sbjct: 847 TTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASAVDA 906

Query: 709 LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSED----SYLQAAN 764
           +        +   AL YV    + EA     ++     LLL + G S+     +  +A  
Sbjct: 907 MDFI-NDATDVNDALGYV-TRFYREASSGAAKKR----LLLFSDGNSQGATPAAIEKAVQ 960

Query: 765 ALTRAGILTFCV 776
              RAGI  F V
Sbjct: 961 EAQRAGIEIFVV 972



 Score = 65.9 bits (159), Expect = 6e-10
 Identities = 84/349 (24%), Positives = 147/349 (42%), Gaps = 45/349 (12%)

Query: 39  DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGE------NDFHFALVQFNGN---PHT 89
           D++F++DSS +IG ++F++ ++F+  V+  L+  E         +  +VQ++ +    H 
Sbjct: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674

Query: 90  EFLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVL 149
                + R  QE+   I ++ ++ G   TG+ L+Y     L  +  +R       + +V+
Sbjct: 675 SLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNR-------IALVI 727

Query: 150 TDGHSKDGL-ALPSAELKSADVNVFAIGVEDA-----DEGALKEIASEPLNMHM------ 197
           TDG S       P   L S  + V ++G++D          L  I+ + L          
Sbjct: 728 TDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLS 787

Query: 198 FNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVN 257
              EN+  L  +    +  V + +  ++     T   IT    ADI  L+DGS + GS N
Sbjct: 788 LVKENYAEL--LEDAFLKNVTAQICIDKKCPDYTC-PITFSSPADITILLDGSASVGSHN 844

Query: 258 FAVILDFLVNLLEK-LPIG----TQQIRVGVVQFS---DEPRTMFSLDTYSTKAQVLGAV 309
           F     F   L E+ L  G       +RV VVQ+S    +     SL        +  AV
Sbjct: 845 FDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASAV 904

Query: 310 KALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPS 358
            A+ F   +  ++  AL +V   +   + G+  +      L+L S G S
Sbjct: 905 DAMDFI-NDATDVNDALGYVTRFYREASSGAAKKR-----LLLFSDGNS 947



 Score = 56.6 bits (135), Expect = 4e-07
 Identities = 88/335 (26%), Positives = 135/335 (40%), Gaps = 60/335 (17%)

Query: 837  DILFLFDGSANL-VGQFPVVRDFLYKIIDELN------VKPEGTRIAVAQYSDDVKVESR 889
            D+LF+ D S ++ +  F + +DF+ K+ID L+       +P  +   V QYS      S+
Sbjct: 615  DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYS-----HSQ 669

Query: 890  FDEHQS--KPEILNL------VKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVL 941
              EH S   P I N+      +K ++   G     G AL Y +  +   S  +RI     
Sbjct: 670  MQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFT-GEALQYTRDQLLPPSPNNRIA---- 724

Query: 942  QFLVLLVAGRSSDRVDG-PASNLKQSGVVPFIFQAKNAD---PAELEQIVLSPAFILAAE 997
               +++  GRS  + D  P + L   G+       K+     P   +  V+S   +  ++
Sbjct: 725  ---LVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQ 781

Query: 998  SLPKIGDLHPQIVNLL----------------KSVHNGAPAPVSGEKDVVFLLDGSEGVR 1041
              P +  +      LL                K      P   S   D+  LLDGS  V 
Sbjct: 782  GRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASVG 841

Query: 1042 S-GFPLLKEFVQRVVESL------DVGQDRVRVAVVQYS--DRTRPE-FYLNSYMNKQDV 1091
            S  F   K F +R+ E        D   D VRVAVVQYS   + RPE   L    N   +
Sbjct: 842  SHNFDTTKRFAKRLAERFLTAGRTDPAHD-VRVAVVQYSGTGQQRPERASLQFLQNYTAL 900

Query: 1092 VNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGS 1126
             +AV  +  +   T +   AL +V R    +S+G+
Sbjct: 901  ASAVDAMDFINDAT-DVNDALGYVTRFYREASSGA 934



 Score = 55.8 bits (133), Expect = 6e-07
 Identities = 70/305 (22%), Positives = 124/305 (40%), Gaps = 44/305 (14%)

Query: 1436 DIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLN------IGPSKVRVGVVQFSNDVFPE-- 1487
            D++F++DSSE +    F   +DFV +++ RL+        P +   GVVQ+S+    E  
Sbjct: 615  DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674

Query: 1488 -FYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVL 1546
                 + R+   + +AI+ L+   G    TG+AL++    L   S  +RI       LV+
Sbjct: 675  SLRSPSIRNVQELKEAIKSLQWMAGGTF-TGEALQYTRDQLLPPSPNNRIA------LVI 727

Query: 1547 VLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNI-----DRTELQTIT--------NDPRLV 1593
              G       +    V+ S GI  + VG +++        +L  I+          P L 
Sbjct: 728  TDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLS 787

Query: 1594 FTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRD 1653
                 + EL  +E+  + +              T P +      ADI  LLDGS +    
Sbjct: 788  LVKENYAEL--LEDAFLKNVTAQICIDKKCPDYTCPIT--FSSPADITILLDGSASVGSH 843

Query: 1654 SFQEVLRFVSEIVDTVYEDG-----DSIQVGLVQYNS------DPTDEFFLKDFSTKRQI 1702
            +F    RF   + +     G       ++V +VQY+       +     FL++++     
Sbjct: 844  NFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASA 903

Query: 1703 IDAIN 1707
            +DA++
Sbjct: 904  VDAMD 908



 Score = 52.8 bits (125), Expect = 5e-06
 Identities = 89/373 (23%), Positives = 151/373 (40%), Gaps = 47/373 (12%)

Query: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKL------PIGTQQIRVGVVQFS-DEPRTMF 294
           D++F++D S + G  NF +  DF+V ++++L           Q   GVVQ+S  + +   
Sbjct: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674

Query: 295 SLDTYSTK--AQVLGAVKALGF-AGGELANIGLALDFVVENHFTRAGGSRV--------- 342
           SL + S +   ++  A+K+L + AGG     G AL +  +     +  +R+         
Sbjct: 675 SLRSPSIRNVQELKEAIKSLQWMAGGTFT--GEALQYTRDQLLPPSPNNRIALVITDGRS 732

Query: 343 --EEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVF 400
             +     + VL S G         VV++    VF F  G+   +    Q +A       
Sbjct: 733 DTQRDTTPLNVLCSPG-------IQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPG 785

Query: 401 TVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLAN 460
                 ++ +L E      V  AQ  I  K P     +   +  DI  L+DGS+++G  N
Sbjct: 786 LSLVKENYAELLEDAFLKNV-TAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHN 844

Query: 461 FNAIRDFIAKVIQR-LEIGQ----DLIQVAVAQYADT--VRPEFYFNTHPTKREVITAVR 513
           F+  + F  ++ +R L  G+      ++VAV QY+ T   RPE            + +  
Sbjct: 845 FDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASAV 904

Query: 514 KMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLD----EISQPA 569
                   A     AL +V      +S+G        K L+L + G S       I +  
Sbjct: 905 DAMDFINDATDVNDALGYVTRFYREASSG-----AAKKRLLLFSDGNSQGATPAAIEKAV 959

Query: 570 QELKRSSIMAFAI 582
           QE +R+ I  F +
Sbjct: 960 QEAQRAGIEIFVV 972



 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 89/358 (24%), Positives = 148/358 (41%), Gaps = 55/358 (15%)

Query: 1230 GKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLD----VGFDTTR--VAVIQFSDDPKV 1282
            G  D++F++D S+S G + F+  +  + +++D L     V F+  +    V+Q+S     
Sbjct: 612  GPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQ 671

Query: 1283 EFL-LNAHSSKD--EVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQF 1339
            E + L + S ++  E++ A++ L+   G     G AL+Y    +      +RI       
Sbjct: 672  EHVSLRSPSIRNVQELKEAIKSLQWMAGGTFT-GEALQYTRDQLLPPSPNNRIA------ 724

Query: 1340 LVLISSGKSDDEVD--------DPAVELKQFGVAP-FTIARNADQEELVKIS-LSPEYV- 1388
             ++I+ G+SD + D         P +++   G+   F     +DQ  ++    L+P    
Sbjct: 725  -LVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGR 783

Query: 1389 --FSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEG 1446
               S+        LE   L  +T     QI        Y  P   S  ADI  L+D S  
Sbjct: 784  PGLSLVKENYAELLEDAFLKNVTA----QICIDKKCPDYTCPITFSSPADITILLDGSAS 839

Query: 1447 VRPDGFAHIRDFVSRIVRR-LNIGPS----KVRVGVVQFS--NDVFPE----FYLKTYRS 1495
            V    F   + F  R+  R L  G +     VRV VVQ+S      PE     +L+ Y +
Sbjct: 840  VGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTA 899

Query: 1496 QAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQ 1553
             A  +DA+  +        +   AL +V R  F + A S       + L+L   G SQ
Sbjct: 900  LASAVDAMDFI----NDATDVNDALGYVTR--FYREASS---GAAKKRLLLFSDGNSQ 948



 Score = 47.0 bits (110), Expect = 3e-04
 Identities = 65/275 (23%), Positives = 112/275 (40%), Gaps = 42/275 (15%)

Query: 639 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD------IGNDNIRVGLVQFSDTPVTE-F 691
           D++F+LD S ++G  NF   +DFV+ +++ L               G+VQ+S + + E  
Sbjct: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674

Query: 692 SLNTYQTKS--DILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLL 749
           SL +   ++  ++   ++ LQ   G G  TG AL Y        +  +RI        L+
Sbjct: 675 SLRSPSIRNVQELKEAIKSLQWMAG-GTFTGEALQYTRDQLLPPSPNNRI-------ALV 726

Query: 750 LTAGQSEDSY-LQAANALTRAGI----------LTFCVGASQANKAELEQIA---FNPSL 795
           +T G+S+        N L   GI            F  G+ Q N    + +A     P L
Sbjct: 727 ITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGL 786

Query: 796 VYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQP---ESKRDILFLFDGSANLVG-Q 851
             + ++++ L  L    ++ +T  +    +      P    S  DI  L DGSA++    
Sbjct: 787 SLVKENYAEL--LEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHN 844

Query: 852 FPVVRDFLYKIIDEL-----NVKPEGTRIAVAQYS 881
           F   + F  ++ +              R+AV QYS
Sbjct: 845 FDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYS 879



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 87/396 (21%), Positives = 160/396 (40%), Gaps = 46/396 (11%)

Query: 1639 DIVFLLDGSINFRRDSFQEVLRFVSEIVDTV-------YEDGDSIQVGLVQY-NSDPTDE 1690
            D++F+LD S +    +F+    FV +++D +       +E G S   G+VQY +S   + 
Sbjct: 615  DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQS-YAGVVQYSHSQMQEH 673

Query: 1691 FFLKDFSTK--RQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAF 1748
              L+  S +  +++ +AI  + +  G    T   L++ R     P   +R       IA 
Sbjct: 674  VSLRSPSIRNVQELKEAIKSLQWMAG-GTFTGEALQYTRDQLLPPSPNNR-------IAL 725

Query: 1749 VITGGKSVEDAQDVSL-ALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQ---E 1804
            VIT G+S        L  L   G++V +VG++++     G    N  +   +   Q    
Sbjct: 726  VITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPG 785

Query: 1805 LSELSEQVLETLHDAMHETL---------CPGVT-DAAKACNLDVILGFDGSRDQNVFVA 1854
            LS + E   E L DA  + +         CP  T     +   D+ +  DGS      V 
Sbjct: 786  LSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSAS----VG 841

Query: 1855 QKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVE----AFDFDEYQPEM 1910
               F++       R+++    +     +  VRV+VV  + +G       +  F +    +
Sbjct: 842  SHNFDT-TKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTAL 900

Query: 1911 LEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVKV-VIHFTDG--ADGDLADLHRASE 1967
                  M   +      D L      +R++S  + K  ++ F+DG       A + +A +
Sbjct: 901  ASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQ 960

Query: 1968 NLRQEGVRALILVGLERVVNLERLMHLEFGRGFMYD 2003
              ++ G+   ++V + R VN   +  L  G+   YD
Sbjct: 961  EAQRAGIEIFVVV-VGRQVNEPHIRVLVTGKTAEYD 995



 Score = 40.0 bits (92), Expect = 0.037
 Identities = 38/169 (22%), Positives = 75/169 (44%), Gaps = 20/169 (11%)

Query: 2618 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2677
            ID+ F+LDS+E+  L  F   K ++  ++ +L      K     +   VVQ++ S+  ++
Sbjct: 614  IDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEH 673

Query: 2678 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLK 2737
             S+    +        + ++L + + + +  + G    G A++YT + +   +PN R   
Sbjct: 674  VSLRSPSIR-------NVQELKEAI-KSLQWMAGGTFTGEALQYTRDQLLPPSPNNR--- 722

Query: 2738 IVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTF 2786
             + L++T    + Q +      L   C     VV      V IK+V+ F
Sbjct: 723  -IALVITDGRSDTQRDTTP---LNVLCSPGIQVV-----SVGIKDVFDF 762



 Score = 33.5 bits (75), Expect = 3.4
 Identities = 33/154 (21%), Positives = 66/154 (42%), Gaps = 21/154 (13%)

Query: 38  ADIIFLVDSSWTIGEEHFQLVREFLYDVV-KSLAVGE----NDFHFALVQFNGNPH---T 89
           ADI  L+D S ++G  +F   + F   +  + L  G     +D   A+VQ++G       
Sbjct: 828 ADITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPE 887

Query: 90  EFLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVL 149
              L   +    + S +  M +I         L Y+ + +   ++G+       + +++ 
Sbjct: 888 RASLQFLQNYTALASAVDAMDFINDATDVNDALGYVTRFYREASSGA-----AKKRLLLF 942

Query: 150 TDGHSKDGLALPSA------ELKSADVNVFAIGV 177
           +DG+S+   A P+A      E + A + +F + V
Sbjct: 943 SDGNSQG--ATPAAIEKAVQEAQRAGIEIFVVVV 974


>gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Homo
            sapiens]
          Length = 1019

 Score =  325 bits (833), Expect = 4e-88
 Identities = 251/776 (32%), Positives = 352/776 (45%), Gaps = 76/776 (9%)

Query: 1935 NKFRQSSPDSVKVVIHF----TDG--ADGDLADLHRASENLRQEGVRALILVGLERVVNL 1988
            N   Q   D  K  +HF    TDG         +   +E  R+EG+R L  V   + +  
Sbjct: 140  NMTEQIRQDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERAREEGIR-LFAVAPNQNLKE 198

Query: 1989 ERLMHLEFGRGFMYDRPLRLNLLD---LDYELAEQLDNIAEKACCGVPCKCSGQRGDRGP 2045
            + L  +      +Y       L D   +D +   ++  + +    G   K S      GP
Sbjct: 199  QGLRDIASTPHELYRNDYATMLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIP-GP 257

Query: 2046 IGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGF---QGCPGQRGVKGSRGFPGE 2102
             G  G +G  G  G  G PG+ G  G +G PG+ G  GF   +G PG +G KG  G  G 
Sbjct: 258  SGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGR 317

Query: 2103 KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKG---ERGDVGIRGDPGN 2159
            KG  G  G +G DG+ G  G  G  G KG+PG RG  G  GE G   ERGD G +GDPG 
Sbjct: 318  KGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGR 377

Query: 2160 PGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPG 2219
            PG+    RGP GE G  G  G  G  G PG PG  G  GG G RGP G  G +G PG  G
Sbjct: 378  PGR----RGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKG 433

Query: 2220 FEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPG 2279
              G  G +G +G  GP GP GL GE G  G +G  G  G  G +G  G  G++G  G+PG
Sbjct: 434  SPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPG 493

Query: 2280 PKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGI 2339
              G  G+ G  G  GD GR G    G RG  GE+G PG  GP+G  G+ GL G  G KG 
Sbjct: 494  DAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGE 553

Query: 2340 RGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD-SIDQCALIQSIKDKCPCCYGPLECPV 2398
            +G   + GPPG  G +G  G PGP G  G  GD  + +C ++  +++ C CC     C  
Sbjct: 554  KGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKRCGA 613

Query: 2399 FPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDL--TIAESNCPRGARVAVVTYNNEVTT 2456
               ++ F +D+SE +    F   ++ V+++VN L     +     G RV VV Y++E T 
Sbjct: 614  L--DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTF 671

Query: 2457 EIRFADSKR---KSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAV 2513
            E    D +R    S   + +KNL+    +      +A+ F      K  R     +K  V
Sbjct: 672  EAIQLDDERIDSLSSFKEAVKNLE--WIAGGTWTPSALKFAYDRLIKESRR----QKTRV 725

Query: 2514 F-FSNTPTRASPQ--------LREAVLKLSDAGITPLFLTRQEDRQLINAL-----QINN 2559
            F    T  R  P+        L +  + ++  GI  +F  + E   L +       Q+ N
Sbjct: 726  FAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKPQQVRN 785

Query: 2560 TAVGHALVLPAGRDLTDFLENVLTCH---VCLDI-CNIDPSCGFGSWRPSFRDRRAAGSD 2615
              +   LV        D +E+VL      VC D+ C  + S    + RP           
Sbjct: 786  MTLFSDLV---AEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRP----------- 831

Query: 2616 VDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMS---PDPKASQHFARVAVVQ 2668
              +D+ F+LD +E      F++ ++++  + R+L ++    DP      ARVA++Q
Sbjct: 832  --VDIVFLLDGSERLGEQNFHKARRFVEQVARRLTLARRDDDPLN----ARVALLQ 881



 Score = 65.1 bits (157), Expect = 1e-09
 Identities = 88/361 (24%), Positives = 154/361 (42%), Gaps = 48/361 (13%)

Query: 1434 AADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNI------GPSKVRVGVVQFSND-VFP 1486
            A D+VF+IDSSE +    F   ++FV  +V RL          +  RVGVVQ+S++  F 
Sbjct: 613  ALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFE 672

Query: 1487 EFYLKTYR--SQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHL 1544
               L   R  S +   +A++ L    G    T  AL+F    L  +S   +         
Sbjct: 673  AIQLDDERIDSLSSFKEAVKNLEWIAGGTW-TPSALKFAYDRLIKESRRQKTR----VFA 727

Query: 1545 VLVLGGKSQ---DDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTI----TNDPRLVFTVR 1597
            V++  G+     DD++  A   R   + ++G+GD   ++ E + +     + P+ V  + 
Sbjct: 728  VVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKPQQVRNMT 787

Query: 1598 EFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPE-------KKKADIVFLLDGSINF 1650
             F +L  + E+ ++        P P  V    P + E       ++  DIVFLLDGS   
Sbjct: 788  LFSDL--VAEKFIDDM-EDVLCPDPQIVCPDLPCQTELSVAQCTQRPVDIVFLLDGSERL 844

Query: 1651 RRDSFQEVLRFVSEIVDTVY-----EDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDA 1705
               +F +  RFV ++   +      +D  + +V L+Q+      +           I +A
Sbjct: 845  GEQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQVAFPLSHNLTAIHEA 904

Query: 1706 INKVVYKGGRHANTKVGLEHLRVNHFV--PEAGSRLDQRVPQIAFV-----ITGGKSVED 1758
            +    Y     ++   G+ H  +N  V  P  G+R   R  +++FV     +TG  S+ +
Sbjct: 905  LETTQYLNS-FSHVGAGVVH-AINAIVRSPRGGAR---RHAELSFVFLTDGVTGNDSLHE 959

Query: 1759 A 1759
            +
Sbjct: 960  S 960



 Score = 60.5 bits (145), Expect = 3e-08
 Identities = 91/368 (24%), Positives = 156/368 (42%), Gaps = 43/368 (11%)

Query: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKL------PIGTQQIRVGVVQFSDEPRTMFS 295
           D++F+ID S + G  NF +  +F++N++ +L      P      RVGVVQ+S E  T  +
Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEG-TFEA 673

Query: 296 LDTYSTKAQVLG----AVKALGF-AGGELANIGL--ALDFVVENHFTRAGGSRVEEGVPQ 348
           +     +   L     AVK L + AGG      L  A D +++   +R   +RV      
Sbjct: 674 IQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKE--SRRQKTRV------ 725

Query: 349 VLVLISAG---PSSDEIRYGVVALKQASVFSFGLGAQAASRAE---LQHIATDDNLVFTV 402
             V+I+ G   P  D++    +  +  +V + G+G     + E   L  IA D      V
Sbjct: 726 FAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKPQ--QV 783

Query: 403 PEFRSFGDL-QEKLLPYIVGVAQRHIVLKPPTIVTQ----VIEVNKR--DIVFLVDGSSA 455
                F DL  EK +  +  V      +  P +  Q    V +  +R  DIVFL+DGS  
Sbjct: 784 RNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRPVDIVFLLDGSER 843

Query: 456 LGLANFNAIRDFIAKVIQRLEIGQD-----LIQVAVAQYADTVRPEFYFNTHPTKREVIT 510
           LG  NF+  R F+ +V +RL + +        +VA+ Q+      +  F        +  
Sbjct: 844 LGEQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQVAFPLSHNLTAIHE 903

Query: 511 AVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQ 570
           A+   + L+ S  + G+ +    N +  S  G          + L  G    D + + A 
Sbjct: 904 ALETTQYLN-SFSHVGAGVVHAINAIVRSPRGGARRHAELSFVFLTDGVTGNDSLHESAH 962

Query: 571 ELKRSSIM 578
            +++ +++
Sbjct: 963 SMRKQNVV 970



 Score = 56.6 bits (135), Expect = 4e-07
 Identities = 69/278 (24%), Positives = 113/278 (40%), Gaps = 28/278 (10%)

Query: 33  KNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAV------GENDFHFALVQFNGN 86
           K   A D++F++DSS +IG  +F L + F+ +VV  L         E      +VQ++  
Sbjct: 609 KRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHE 668

Query: 87  PHTEFL-LNTYR--TKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVP 143
              E + L+  R  +       + N+ +I G   T   L++     + ++   +      
Sbjct: 669 GTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQK----TR 724

Query: 144 QVIVVLTDG-HSKDGLALPSAELKSADVNVFAIGVEDA-----DEGALKEIA----SEPL 193
              VV+TDG H      L    L   DV V AIG+ D      +   L  IA     +  
Sbjct: 725 VFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKPQQVR 784

Query: 194 NMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNT 253
           NM +F+        D + +++      V P+    TE       Q   DI+FL+DGS   
Sbjct: 785 NMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRPVDIVFLLDGSERL 844

Query: 254 GSVNFAVILDFLVNLLEKLPIGTQ-----QIRVGVVQF 286
           G  NF     F+  +  +L +  +       RV ++QF
Sbjct: 845 GEQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQF 882



 Score = 52.8 bits (125), Expect = 5e-06
 Identities = 90/370 (24%), Positives = 149/370 (40%), Gaps = 56/370 (15%)

Query: 445 DIVFLVDGSSALGLANFNAIRDFIAKVIQRL-EIGQDL-----IQVAVAQYADTVRPEFY 498
           D+VF++D S ++G  NF   ++F+  V+ RL  I +D       +V V QY+     E  
Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSH----EGT 670

Query: 499 FNTHPTKREVIT-------AVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPK 551
           F       E I        AV+ ++ + G   +T SAL F  + L   S   +       
Sbjct: 671 FEAIQLDDERIDSLSSFKEAVKNLEWIAGGT-WTPSALKFAYDRLIKESRRQKTRV---- 725

Query: 552 LLVLITGGKSL---DEISQPAQELKRSSIMAFAIGNKGADQAELEE---IAFD------- 598
             V+IT G+     D+++  A   +  ++ A  IG+   ++ E E    IA D       
Sbjct: 726 FAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKPQQVRN 785

Query: 599 ----SSLVFIPAEFRAAPLQGML---PGLLAP---LRTLSGTPEVHSNKRDIIFLLDGSA 648
               S LV   AE     ++ +L   P ++ P    +T     +      DI+FLLDGS 
Sbjct: 786 MTLFSDLV---AEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRPVDIVFLLDGSE 842

Query: 649 NVGKTNFPYVRDFVMNLVNSLDIGND-----NIRVGLVQFSDTPVTEFSLNTYQTKSDIL 703
            +G+ NF   R FV  +   L +        N RV L+QF      + +       + I 
Sbjct: 843 RLGEQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQVAFPLSHNLTAIH 902

Query: 704 GHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAG-QSEDSYLQA 762
             L   Q            +  + A   +  GG+  R H     + LT G    DS  ++
Sbjct: 903 EALETTQYLNSFSHVGAGVVHAINAIVRSPRGGA--RRHAELSFVFLTDGVTGNDSLHES 960

Query: 763 ANALTRAGIL 772
           A+++ +  ++
Sbjct: 961 AHSMRKQNVV 970



 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 89/385 (23%), Positives = 153/385 (39%), Gaps = 33/385 (8%)

Query: 1026 GEKDVVFLLDGSEGVR-SGFPLLKEFVQRVVESLDV------GQDRVRVAVVQYS-DRTR 1077
            G  DVVF++D SE +  + F L K FV  VV  L         +   RV VVQYS + T 
Sbjct: 612  GALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTF 671

Query: 1078 PEFYLNSYM--NKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQL 1135
                L+     +      AV+ L  + G T  T +AL+F    ++  S   +        
Sbjct: 672  EAIQLDDERIDSLSSFKEAVKNLEWIAGGTW-TPSALKFAYDRLIKESRRQKTRV----F 726

Query: 1136 LIVLTADRSG--DDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQ 1193
             +V+T  R    DD  N   +  R   V   IGIG+    + ++ +            R 
Sbjct: 727  AVVITDGRHDPRDDDLNLRALCDRDVTVT-AIGIGDMFHEKHESENLYSIACDKPQQVRN 785

Query: 1194 LGTVQQVISERVTQLTREELSRLQPVLQP-LP-----SPGVGGKR--DVVFLIDGSQSAG 1245
            +     +++E+      + L     ++ P LP     S     +R  D+VFL+DGS+  G
Sbjct: 786  MTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRPVDIVFLLDGSERLG 845

Query: 1246 PE-FQYVRTLIERLVDYLDVGFD-----TTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAV 1299
             + F   R  +E++   L +          RVA++QF    + +       +   +  A+
Sbjct: 846  EQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQVAFPLSHNLTAIHEAL 905

Query: 1300 QRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVEL 1359
            +  +       +VG  + +    I + P G         F+ L      +D + + A  +
Sbjct: 906  ETTQYLNSFS-HVGAGVVHAINAIVRSPRGGARRHAELSFVFLTDGVTGNDSLHESAHSM 964

Query: 1360 KQFGVAPFTIARNADQEELVKISLS 1384
            ++  V P  +A  +D +  V  +LS
Sbjct: 965  RKQNVVPTVLALGSDVDMDVLTTLS 989



 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 87/366 (23%), Positives = 150/366 (40%), Gaps = 39/366 (10%)

Query: 639 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD-IGND-----NIRVGLVQFSDTPVTEFS 692
           D++F++D S ++G TNF   ++FV+N+VN L  I  D       RVG+VQ+S     E +
Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFE-A 673

Query: 693 LNTYQTKSDILGHLRQ----LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLL 748
           +     + D L   ++    L+   G G  T SAL + Y     E+     R+      +
Sbjct: 674 IQLDDERIDSLSSFKEAVKNLEWIAG-GTWTPSALKFAYDRLIKESR----RQKTRVFAV 728

Query: 749 LLTAGQSE--DSYLQAANALTR-AGILTFCVGASQANKAELEQI----AFNPSLVYLMDD 801
           ++T G+ +  D  L       R   +    +G     K E E +       P  V  M  
Sbjct: 729 VITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKPQQVRNMTL 788

Query: 802 FSSLPALP-----QQLIQPLTTYVSGGV---EEVPLAQ-PESKRDILFLFDGSANLVGQ- 851
           FS L A       + ++ P    V   +    E+ +AQ  +   DI+FL DGS  L  Q 
Sbjct: 789 FSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRPVDIVFLLDGSERLGEQN 848

Query: 852 FPVVRDFLYKIIDELNV-----KPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRM 906
           F   R F+ ++   L +      P   R+A+ Q+    + +  F    +   I   ++  
Sbjct: 849 FHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQVAFPLSHNLTAIHEALETT 908

Query: 907 KIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQS 966
           +     + ++G  + +A   I     G       L F+ L      +D +   A ++++ 
Sbjct: 909 QYLNSFS-HVGAGVVHAINAIVRSPRGGARRHAELSFVFLTDGVTGNDSLHESAHSMRKQ 967

Query: 967 GVVPFI 972
            VVP +
Sbjct: 968 NVVPTV 973



 Score = 50.4 bits (119), Expect = 3e-05
 Identities = 67/276 (24%), Positives = 112/276 (40%), Gaps = 30/276 (10%)

Query: 1230 GKRDVVFLIDGSQSAG-PEFQYVRTLIERLVDYL-----DVGFDT-TRVAVIQFSDDPKV 1282
            G  DVVF+ID S+S G   F   +  +  +V+ L     D   +T TRV V+Q+S +   
Sbjct: 612  GALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTF 671

Query: 1283 EFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVL 1342
            E +       D + +  + +  K    I  G       +  + R +     +    F V+
Sbjct: 672  EAIQLDDERIDSLSSFKEAV--KNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVFAVV 729

Query: 1343 ISSGKSDDEVDD--------PAVELKQFGVAPFTIARNADQEELVKISLS-PEYVFSVST 1393
            I+ G+ D   DD          V +   G+      ++ + E L  I+   P+ V +++ 
Sbjct: 730  ITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKH-ESENLYSIACDKPQQVRNMTL 788

Query: 1394 FRELPSLEQKLLTPITTLTSEQIQ----KLLASTRYPPPAVESDAADIVFLIDSSEGVRP 1449
            F +L  + +K +  +  +     Q     L   T            DIVFL+D SE +  
Sbjct: 789  FSDL--VAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRPVDIVFLLDGSERLGE 846

Query: 1450 DGFAHIRDFVSRIVRRLNIG-----PSKVRVGVVQF 1480
              F   R FV ++ RRL +      P   RV ++QF
Sbjct: 847  QNFHKARRFVEQVARRLTLARRDDDPLNARVALLQF 882



 Score = 42.0 bits (97), Expect = 0.010
 Identities = 38/159 (23%), Positives = 64/159 (40%), Gaps = 10/159 (6%)

Query: 39  DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGEND-----FHFALVQFNGNPHTEFLL 93
           DI+FL+D S  +GE++F   R F+  V + L +   D        AL+QF G    +   
Sbjct: 833 DIVFLLDGSERLGEQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQVAF 892

Query: 94  NTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDG- 152
                   +   +    Y+   +  G G+ + + + +    G  A        V LTDG 
Sbjct: 893 PLSHNLTAIHEALETTQYLNSFSHVGAGVVHAINAIVRSPRGG-ARRHAELSFVFLTDGV 951

Query: 153 HSKDGLALPSAELKSADV--NVFAIGVEDADEGALKEIA 189
              D L   +  ++  +V   V A+G  D D   L  ++
Sbjct: 952 TGNDSLHESAHSMRKQNVVPTVLALG-SDVDMDVLTTLS 989



 Score = 34.7 bits (78), Expect = 1.5
 Identities = 22/89 (24%), Positives = 50/89 (56%), Gaps = 3/89 (3%)

Query: 2618 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLD-MSPDPKASQHFARVAVVQHAPSESVD 2676
            +D+ F++DS+E+     F   K ++  +V +L  ++ DPK S+   RV VVQ++   + +
Sbjct: 614  LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPK-SETGTRVGVVQYSHEGTFE 672

Query: 2677 NASMPPVKVEFSLTDYGSKEKLVDFLSRG 2705
               +   +++ SL+ +    K +++++ G
Sbjct: 673  AIQLDDERID-SLSSFKEAVKNLEWIAGG 700


>gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [Homo
            sapiens]
          Length = 828

 Score =  317 bits (812), Expect = 1e-85
 Identities = 205/564 (36%), Positives = 271/564 (48%), Gaps = 29/564 (5%)

Query: 1935 NKFRQSSPDSVKVVIHF----TDG--ADGDLADLHRASENLRQEGVRALILVGLERVVNL 1988
            N   Q   D  K  +HF    TDG         +   +E  R+EG+R L  V   + +  
Sbjct: 140  NMTEQIRQDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERAREEGIR-LFAVAPNQNLKE 198

Query: 1989 ERLMHLEFGRGFMYDRPLRLNLLD---LDYELAEQLDNIAEKACCGVPCKCSGQRGDRGP 2045
            + L  +      +Y       L D   +D +   ++  + +    G   K S      GP
Sbjct: 199  QGLRDIASTPHELYRNDYATMLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIP-GP 257

Query: 2046 IGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGF---QGCPGQRGVKGSRGFPGE 2102
             G  G +G  G  G  G PG+ G  G +G PG+ G  GF   +G PG +G KG  G  G 
Sbjct: 258  SGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGR 317

Query: 2103 KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKG---ERGDVGIRGDPGN 2159
            KG  G  G +G DG+ G  G  G  G KG+PG RG  G  GE G   ERGD G +GDPG 
Sbjct: 318  KGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGR 377

Query: 2160 PGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPG 2219
            PG+    RGP GE G  G  G  G  G PG PG  G  GG G RGP G  G +G PG  G
Sbjct: 378  PGR----RGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKG 433

Query: 2220 FEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPG 2279
              G  G +G +G  GP GP GL GE G  G +G  G  G  G +G  G  G++G  G+PG
Sbjct: 434  SPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPG 493

Query: 2280 PKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGI 2339
              G  G+ G  G  GD GR G    G RG  GE+G PG  GP+G  G+ GL G  G KG 
Sbjct: 494  DAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGE 553

Query: 2340 RGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD-SIDQCALIQSIKDKCPCCYGPLECPV 2398
            +G   + GPPG  G +G  G PGP G  G  GD  + +C ++  +++ C CC     C  
Sbjct: 554  KGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKRCGA 613

Query: 2399 FPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDL--TIAESNCPRGARVAVVTYNNEVTT 2456
               ++ F +D+SE +    F   ++ V+++VN L     +     G RV VV Y++E T 
Sbjct: 614  L--DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTF 671

Query: 2457 EIRFADSKR---KSVLLDKIKNLQ 2477
            E    D +R    S   + +KNL+
Sbjct: 672  EAIQLDDERIDSLSSFKEAVKNLE 695



 Score = 45.8 bits (107), Expect = 7e-04
 Identities = 45/165 (27%), Positives = 75/165 (45%), Gaps = 17/165 (10%)

Query: 1434 AADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNI------GPSKVRVGVVQFSND-VFP 1486
            A D+VF+IDSSE +    F   ++FV  +V RL          +  RVGVVQ+S++  F 
Sbjct: 613  ALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFE 672

Query: 1487 EFYLKTYR--SQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHL 1544
               L   R  S +   +A++ L    G    T  AL+F    L  +S   +         
Sbjct: 673  AIQLDDERIDSLSSFKEAVKNLEWIAGGTW-TPSALKFAYDRLIKESRRQKTR----VFA 727

Query: 1545 VLVLGGK---SQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTI 1586
            V++  G+     DD++  A   R   + ++G+GD   ++ E + +
Sbjct: 728  VVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENL 772



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 35/112 (31%), Positives = 56/112 (50%), Gaps = 12/112 (10%)

Query: 639 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD-IGND-----NIRVGLVQFSDTPVTEFS 692
           D++F++D S ++G TNF   ++FV+N+VN L  I  D       RVG+VQ+S     E +
Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFE-A 673

Query: 693 LNTYQTKSDILGHLRQ----LQLQGGSGLNTGSALSYVYANHFTEAGGSRIR 740
           +     + D L   ++    L+   G G  T SAL + Y     E+   + R
Sbjct: 674 IQLDDERIDSLSSFKEAVKNLEWIAG-GTWTPSALKFAYDRLIKESRRQKTR 724



 Score = 40.8 bits (94), Expect = 0.022
 Identities = 41/157 (26%), Positives = 67/157 (42%), Gaps = 14/157 (8%)

Query: 33  KNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAV------GENDFHFALVQFNGN 86
           K   A D++F++DSS +IG  +F L + F+ +VV  L         E      +VQ++  
Sbjct: 609 KRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHE 668

Query: 87  PHTEFL-LNTYR--TKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVP 143
              E + L+  R  +       + N+ +I G   T   L++     + ++   +      
Sbjct: 669 GTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQK----TR 724

Query: 144 QVIVVLTDG-HSKDGLALPSAELKSADVNVFAIGVED 179
              VV+TDG H      L    L   DV V AIG+ D
Sbjct: 725 VFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGD 761



 Score = 39.7 bits (91), Expect = 0.048
 Identities = 20/54 (37%), Positives = 32/54 (59%), Gaps = 6/54 (11%)

Query: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKL------PIGTQQIRVGVVQFSDE 289
           D++F+ID S + G  NF +  +F++N++ +L      P      RVGVVQ+S E
Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHE 668



 Score = 35.0 bits (79), Expect = 1.2
 Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 25/167 (14%)

Query: 445 DIVFLVDGSSALGLANFNAIRDFIAKVIQRL-EIGQDL-----IQVAVAQYADTVRPEFY 498
           D+VF++D S ++G  NF   ++F+  V+ RL  I +D       +V V QY+     E  
Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSH----EGT 670

Query: 499 FNTHPTKREVI-------TAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPK 551
           F       E I        AV+ ++ + G   +T SAL F  + L   S   +       
Sbjct: 671 FEAIQLDDERIDSLSSFKEAVKNLEWIAGGT-WTPSALKFAYDRLIKESRRQKTR----V 725

Query: 552 LLVLITGGK---SLDEISQPAQELKRSSIMAFAIGNKGADQAELEEI 595
             V+IT G+     D+++  A   +  ++ A  IG+   ++ E E +
Sbjct: 726 FAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENL 772



 Score = 34.7 bits (78), Expect = 1.5
 Identities = 22/89 (24%), Positives = 50/89 (56%), Gaps = 3/89 (3%)

Query: 2618 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLD-MSPDPKASQHFARVAVVQHAPSESVD 2676
            +D+ F++DS+E+     F   K ++  +V +L  ++ DPK S+   RV VVQ++   + +
Sbjct: 614  LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPK-SETGTRVGVVQYSHEGTFE 672

Query: 2677 NASMPPVKVEFSLTDYGSKEKLVDFLSRG 2705
               +   +++ SL+ +    K +++++ G
Sbjct: 673  AIQLDDERID-SLSSFKEAVKNLEWIAGG 700


>gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Homo
            sapiens]
          Length = 918

 Score =  317 bits (812), Expect = 1e-85
 Identities = 205/564 (36%), Positives = 271/564 (48%), Gaps = 29/564 (5%)

Query: 1935 NKFRQSSPDSVKVVIHF----TDG--ADGDLADLHRASENLRQEGVRALILVGLERVVNL 1988
            N   Q   D  K  +HF    TDG         +   +E  R+EG+R L  V   + +  
Sbjct: 140  NMTEQIRQDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERAREEGIR-LFAVAPNQNLKE 198

Query: 1989 ERLMHLEFGRGFMYDRPLRLNLLD---LDYELAEQLDNIAEKACCGVPCKCSGQRGDRGP 2045
            + L  +      +Y       L D   +D +   ++  + +    G   K S      GP
Sbjct: 199  QGLRDIASTPHELYRNDYATMLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIP-GP 257

Query: 2046 IGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGF---QGCPGQRGVKGSRGFPGE 2102
             G  G +G  G  G  G PG+ G  G +G PG+ G  GF   +G PG +G KG  G  G 
Sbjct: 258  SGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGR 317

Query: 2103 KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKG---ERGDVGIRGDPGN 2159
            KG  G  G +G DG+ G  G  G  G KG+PG RG  G  GE G   ERGD G +GDPG 
Sbjct: 318  KGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGR 377

Query: 2160 PGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPG 2219
            PG+    RGP GE G  G  G  G  G PG PG  G  GG G RGP G  G +G PG  G
Sbjct: 378  PGR----RGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKG 433

Query: 2220 FEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPG 2279
              G  G +G +G  GP GP GL GE G  G +G  G  G  G +G  G  G++G  G+PG
Sbjct: 434  SPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPG 493

Query: 2280 PKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGI 2339
              G  G+ G  G  GD GR G    G RG  GE+G PG  GP+G  G+ GL G  G KG 
Sbjct: 494  DAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGE 553

Query: 2340 RGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD-SIDQCALIQSIKDKCPCCYGPLECPV 2398
            +G   + GPPG  G +G  G PGP G  G  GD  + +C ++  +++ C CC     C  
Sbjct: 554  KGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKRCGA 613

Query: 2399 FPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDL--TIAESNCPRGARVAVVTYNNEVTT 2456
               ++ F +D+SE +    F   ++ V+++VN L     +     G RV VV Y++E T 
Sbjct: 614  L--DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTF 671

Query: 2457 EIRFADSKR---KSVLLDKIKNLQ 2477
            E    D +R    S   + +KNL+
Sbjct: 672  EAIQLDDERIDSLSSFKEAVKNLE 695



 Score = 45.8 bits (107), Expect = 7e-04
 Identities = 45/165 (27%), Positives = 75/165 (45%), Gaps = 17/165 (10%)

Query: 1434 AADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNI------GPSKVRVGVVQFSND-VFP 1486
            A D+VF+IDSSE +    F   ++FV  +V RL          +  RVGVVQ+S++  F 
Sbjct: 613  ALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFE 672

Query: 1487 EFYLKTYR--SQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHL 1544
               L   R  S +   +A++ L    G    T  AL+F    L  +S   +         
Sbjct: 673  AIQLDDERIDSLSSFKEAVKNLEWIAGGTW-TPSALKFAYDRLIKESRRQKTR----VFA 727

Query: 1545 VLVLGGK---SQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTI 1586
            V++  G+     DD++  A   R   + ++G+GD   ++ E + +
Sbjct: 728  VVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENL 772



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 35/112 (31%), Positives = 56/112 (50%), Gaps = 12/112 (10%)

Query: 639 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD-IGND-----NIRVGLVQFSDTPVTEFS 692
           D++F++D S ++G TNF   ++FV+N+VN L  I  D       RVG+VQ+S     E +
Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFE-A 673

Query: 693 LNTYQTKSDILGHLRQ----LQLQGGSGLNTGSALSYVYANHFTEAGGSRIR 740
           +     + D L   ++    L+   G G  T SAL + Y     E+   + R
Sbjct: 674 IQLDDERIDSLSSFKEAVKNLEWIAG-GTWTPSALKFAYDRLIKESRRQKTR 724



 Score = 40.8 bits (94), Expect = 0.022
 Identities = 41/157 (26%), Positives = 67/157 (42%), Gaps = 14/157 (8%)

Query: 33  KNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAV------GENDFHFALVQFNGN 86
           K   A D++F++DSS +IG  +F L + F+ +VV  L         E      +VQ++  
Sbjct: 609 KRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHE 668

Query: 87  PHTEFL-LNTYR--TKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVP 143
              E + L+  R  +       + N+ +I G   T   L++     + ++   +      
Sbjct: 669 GTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQK----TR 724

Query: 144 QVIVVLTDG-HSKDGLALPSAELKSADVNVFAIGVED 179
              VV+TDG H      L    L   DV V AIG+ D
Sbjct: 725 VFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGD 761



 Score = 39.7 bits (91), Expect = 0.048
 Identities = 20/54 (37%), Positives = 32/54 (59%), Gaps = 6/54 (11%)

Query: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKL------PIGTQQIRVGVVQFSDE 289
           D++F+ID S + G  NF +  +F++N++ +L      P      RVGVVQ+S E
Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHE 668



 Score = 35.0 bits (79), Expect = 1.2
 Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 25/167 (14%)

Query: 445 DIVFLVDGSSALGLANFNAIRDFIAKVIQRL-EIGQDL-----IQVAVAQYADTVRPEFY 498
           D+VF++D S ++G  NF   ++F+  V+ RL  I +D       +V V QY+     E  
Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSH----EGT 670

Query: 499 FNTHPTKREVI-------TAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPK 551
           F       E I        AV+ ++ + G   +T SAL F  + L   S   +       
Sbjct: 671 FEAIQLDDERIDSLSSFKEAVKNLEWIAGGT-WTPSALKFAYDRLIKESRRQKTR----V 725

Query: 552 LLVLITGGK---SLDEISQPAQELKRSSIMAFAIGNKGADQAELEEI 595
             V+IT G+     D+++  A   +  ++ A  IG+   ++ E E +
Sbjct: 726 FAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENL 772



 Score = 34.7 bits (78), Expect = 1.5
 Identities = 22/89 (24%), Positives = 50/89 (56%), Gaps = 3/89 (3%)

Query: 2618 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLD-MSPDPKASQHFARVAVVQHAPSESVD 2676
            +D+ F++DS+E+     F   K ++  +V +L  ++ DPK S+   RV VVQ++   + +
Sbjct: 614  LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPK-SETGTRVGVVQYSHEGTFE 672

Query: 2677 NASMPPVKVEFSLTDYGSKEKLVDFLSRG 2705
               +   +++ SL+ +    K +++++ G
Sbjct: 673  AIQLDDERID-SLSSFKEAVKNLEWIAGG 700


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  307 bits (787), Expect = 9e-83
 Identities = 170/372 (45%), Positives = 205/372 (55%), Gaps = 33/372 (8%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGE---DGYRGYPGDEGGPGERGPPGVNGTQGFQGCPG 2089
            P   +G+RG++GP GS G +G+PG     G  G PG++G PG+ G PG +G +G +G PG
Sbjct: 624  PAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPG 683

Query: 2090 QRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGE---KGNPGRRGDKGPRGEKG 2146
            +RGV+G  G  G +G  G  G DG  G+ G  G PGS G    +G PG RG  G  G KG
Sbjct: 684  ERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKG 743

Query: 2147 ERGDVGIRGDPGNPGQDSQER--------------GPKGETGDLGPMGVPGRDGVPGGPG 2192
            +RGD G +G  G+PG+D                  G KGE+G  GP G  G  G PG  G
Sbjct: 744  DRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRG 803

Query: 2193 ETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRG 2252
            E G  G  G  GPPGA G  G  G+PG  G +G  G  GPAGPAGPPG IG  G  G +G
Sbjct: 804  EPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKG 863

Query: 2253 SGGAAGAPGER---------GRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VG 2302
            + G+AG PG           G  GP G  G PG PGP G  G +GPRGETG  GR G VG
Sbjct: 864  ARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVG 923

Query: 2303 SEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGI---RGRRGNSGPPGIVGQKGDPG 2359
              G  G  GE+G PG  GP G PG PG  G  G +G+    G+RG  G PG+ G  G+PG
Sbjct: 924  PPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPG 983

Query: 2360 YPGPAGPKGNRG 2371
              GP+G  G RG
Sbjct: 984  KQGPSGASGERG 995



 Score =  280 bits (715), Expect = 2e-74
 Identities = 166/372 (44%), Positives = 186/372 (50%), Gaps = 33/372 (8%)

Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPG---VNGTQ 2082
            E+   G+P    G +GDRG  G  G  G PG+DG RG  G  G PG  G PG    +G  
Sbjct: 732  ERGAAGLP----GPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPS 787

Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142
            G  G  G RG  G RG PG  G  G  G  G DG+ G KG PG +G KG+ G  G  GP 
Sbjct: 788  GPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPA 847

Query: 2143 GEKGERGDVGI------RGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGK 2196
            G  G  G+VG       RG  G PG      G  G  G +GP G  G  G PG PG  GK
Sbjct: 848  GPPGPIGNVGAPGAKGARGSAGPPGAT----GFPGAAGRVGPPGPSGNAGPPGPPGPAGK 903

Query: 2197 NGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGA 2256
             GG G RG  G  G  G  G PG  G  G +G+ G  GPAG PG  G QGI+G RG  G 
Sbjct: 904  EGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGL 963

Query: 2257 AGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGP---------RGETGDDGRDGV------ 2301
             G  GERG  G  G  GEPG+ GP G  G RGP          G  G+ GR+G       
Sbjct: 964  PGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGS 1023

Query: 2302 -GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGY 2360
             G +G  G KG+RG  G  GP G PG PG  G  GP G  G RG +GP G  G  G  G 
Sbjct: 1024 PGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGA 1083

Query: 2361 PGPAGPKGNRGD 2372
             GPAGP+G RGD
Sbjct: 1084 RGPAGPQGPRGD 1095



 Score =  277 bits (708), Expect = 1e-73
 Identities = 158/349 (45%), Positives = 183/349 (52%), Gaps = 18/349 (5%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096
            +G +GD GP G  GP G PG  G  G PG +G  G  GPPG  G  G  G  G  G  G+
Sbjct: 832  AGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGN 891

Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGD 2156
             G PG  G  G+ G  G  GE G  G PG  G  G PG      P GEKG  G  G  G 
Sbjct: 892  AGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPG------PAGEKGSPGADGPAGA 945

Query: 2157 PGNPGQD--SQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGG 2214
            PG PG    + +RG  G  G  G  G PG  G  G PG+ G +G  G RGPPG  G  G 
Sbjct: 946  PGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGL 1005

Query: 2215 PGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGE 2274
             G PG  G +G  GA+G  G  G PG  G++G +GP G  GA GAPG  G  GP G+ G+
Sbjct: 1006 AGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGD 1065

Query: 2275 PGEPGPKGG------IGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGY---PGPKGN 2324
             GE GP G       +G RGP G  G  G  G  G +G RG KG RGF G    PGP G+
Sbjct: 1066 RGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGS 1125

Query: 2325 PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373
            PGE G +G +GP G RG  G++G PG  G  G PG  GP GP+G  GD+
Sbjct: 1126 PGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDA 1174



 Score =  273 bits (699), Expect = 2e-72
 Identities = 155/350 (44%), Positives = 185/350 (52%), Gaps = 15/350 (4%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096
            +G +G+ GP+G  GP G  GE+G RG  G+ G  G  GPPG  G  G +G PG  GV G 
Sbjct: 445  TGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGP 504

Query: 2097 RGFPGEKGEVGEIGLDGLDGE---DGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI 2153
            +G  GE+G  G  G  G  GE    G+ GLPG+ G  G+PG  G  G  G  G  G  G 
Sbjct: 505  KGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGR 564

Query: 2154 RGDPGNPGQDSQER-----GPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208
             G PG PG   Q       GPKG  G+ G  G  G  G PG  G  GK+G  G +GPPG 
Sbjct: 565  PGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGP 624

Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2268
             G  G  G+ G  G  G +G  GPAGP G  G  GEQG+ G  G+ G +GA GERG  G 
Sbjct: 625  AGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGE 684

Query: 2269 LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV----GSEGRRGKKGERGFPGYPGPKGN 2324
             G +G PG  GP+G  G  G  G  GD G  G     G+ G +G  GERG  G PGPKG+
Sbjct: 685  RGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGD 744

Query: 2325 PGE---PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
             G+    G +G+ G  G+RG  G  GPPG  G  GD G  GP+GP G  G
Sbjct: 745  RGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTG 794



 Score =  273 bits (698), Expect = 2e-72
 Identities = 176/410 (42%), Positives = 197/410 (48%), Gaps = 64/410 (15%)

Query: 2026 EKACCGV----PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGER---GPPGV 2078
            EK+  G+    P   SG RG  GP G+ GP+G  G  G  G PG  G  G R   GPPG 
Sbjct: 169  EKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGK 228

Query: 2079 NGTQGFQGCPGQ------------RGVKGSRGFPGEKGEVGEIGLDGLDGE---DGDKGL 2123
            NG  G  G PG+            RG+ G+ G PG KG  G  GLDG  G+    G KG 
Sbjct: 229  NGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGE 288

Query: 2124 PGSSGEKGNPGRRGDKGPRGEKGE---------RGDVGIRGDPGNPGQDSQ--------- 2165
            PGS GE G PG+ G +G  GE+G          RG+ G  G  G PG             
Sbjct: 289  PGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGA 348

Query: 2166 -----ERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGP---GQ 2217
                 E GP+G  G  GP GV G  G PG  G  G  G  G  G PGAKG  G P   G 
Sbjct: 349  VGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGA 408

Query: 2218 PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP------LGR 2271
            PGF G +G  G QGP GP GP G  GE G  G +G  GA G PG  G  GP       G+
Sbjct: 409  PGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGK 468

Query: 2272 KGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGE--- 2327
            +G  GEPGP G  G  G RG  G  G  G  G  G +G  GERG PG  GPKG+PGE   
Sbjct: 469  RGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGR 528

Query: 2328 ------PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
                  PG  G TG  G  G  G +GPPG  GQ G PG PGP G +G  G
Sbjct: 529  PGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAG 578



 Score =  272 bits (696), Expect = 3e-72
 Identities = 163/392 (41%), Positives = 194/392 (49%), Gaps = 53/392 (13%)

Query: 2023 NIAEKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQ 2082
            N A +   G   K +G     GP+G  GP+G+PG  G  G  G +G PGE G PG +G  
Sbjct: 158  NFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPM 217

Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142
            G +G PG  G  G  G  G+ G  GE    G  G  G +GLPG++G  G  G RG  G  
Sbjct: 218  GPRGPPGPPGKNGDDGEAGKPGRPGE---RGPPGPQGARGLPGTAGLPGMKGHRGFSGLD 274

Query: 2143 GEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGET---GKNGG 2199
            G KG+ G  G +G+PG+PG++       G  G +GP G+PG  G PG PG     G +G 
Sbjct: 275  GAKGDAGPAGPKGEPGSPGEN-------GAPGQMGPRGLPGERGRPGAPGPAGARGNDGA 327

Query: 2200 FGRRGPPGAKGNKGGPGQP---------------GFEGEQGTRGAQGP------AGPAGP 2238
             G  GPPG  G  G PG P               G EG QG RG  GP      AGPAG 
Sbjct: 328  TGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGN 387

Query: 2239 PGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGR 2298
            PG  G+ G  G  G+ G AGAPG  G  GP G +G  G PGPKG  G  G  G  GD G 
Sbjct: 388  PGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGA 447

Query: 2299 DG-------------VGSEGRRGKKGE---RGFPGYPGPKGNPGE---PGLNGTTGPKGI 2339
             G              G EG+RG +GE    G PG PG +G PG    PG +G  GPKG 
Sbjct: 448  KGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGP 507

Query: 2340 RGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
             G RG+ GP G  G  G+ G PG AG  G +G
Sbjct: 508  AGERGSPGPAGPKGSPGEAGRPGEAGLPGAKG 539



 Score =  271 bits (692), Expect = 1e-71
 Identities = 164/385 (42%), Positives = 187/385 (48%), Gaps = 54/385 (14%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPG------------DEGGPGERGP---PGVNGTQ 2082
            G RG+ GP G  GP G  G  G RG+PG            + G PG  GP   PG  G  
Sbjct: 470  GARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRP 529

Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142
            G  G PG +G+ GS G PG  G+ G  G  G DG  G  G PG+ G+ G  G  G KG  
Sbjct: 530  GEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAA 589

Query: 2143 GEKGERGDVGIRGDPGNPGQDSQE-----------RGPKGETGDLGPMGVPGRDGVP--- 2188
            GE G+ G+ G+ G PG  G   ++            GP GE G+ GP G PG  G+P   
Sbjct: 590  GEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPA 649

Query: 2189 GGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGIS 2248
            G PGE GK G  G  G  GA G  G  G+ GF GE   RG QGP GPAGP G  G  G  
Sbjct: 650  GPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGE---RGVQGPPGPAGPRGANGAPGND 706

Query: 2249 GPRGSGGAAGAPGERGRTGPLGRKGEPGE---PGPKGGIGNRGPRGETGDDGRDGV---- 2301
            G +G  GA GAPG +G  G  G  GE G    PGPKG  G+ GP+G  G  G+DGV    
Sbjct: 707  GAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLT 766

Query: 2302 ---------------GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNS 2346
                           G  G  G  G  G  G PG +G PG PG  G  GP G  G+ G  
Sbjct: 767  GPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAK 826

Query: 2347 GPPGIVGQKGDPGYPGPAGPKGNRG 2371
            G PG  G KGD G PGPAGP G  G
Sbjct: 827  GEPGDAGAKGDAGPPGPAGPAGPPG 851



 Score =  270 bits (691), Expect = 1e-71
 Identities = 169/420 (40%), Positives = 205/420 (48%), Gaps = 60/420 (14%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGY---------RGYPGDEGGPGERGP---PGVNGTQGFQ 2085
            G+ G +GP GS GP+G+ GE G           G PG +G PG +G    PG+ G  GF 
Sbjct: 353  GEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFP 412

Query: 2086 GCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEK 2145
            G  G  G +G  G PG KG  GE G  G  G+ G KG PG  G +G PG  G++G RG +
Sbjct: 413  GARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGAR 472

Query: 2146 GERGDVGIRGDPGN---------PGQD--SQERGPKGETGDLGP---------------M 2179
            GE G  G+ G PG          PG D  +  +GP GE G  GP                
Sbjct: 473  GEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEA 532

Query: 2180 GVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPP 2239
            G+PG  G+ G PG  G +G  G  GP G  G  G PG PG  G+ G  G  GP G AG P
Sbjct: 533  GLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEP 592

Query: 2240 GLIGEQGISGPRGSGGAAGAPGE---RGRTGPLGRKGEPGEPGPKGGIGNR------GPR 2290
            G  GE+G+ GP G+ G AG  GE   +G  GP G  GE GE GP G  G +      GP 
Sbjct: 593  GKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPP 652

Query: 2291 GETGDDGRDGV----GSEGRRGKKGERGFPGY---------PGPKGNPGEPGLNGTTGPK 2337
            GE G  G  GV    G+ G  G +GERGFPG           GP+G  G PG +G  G  
Sbjct: 653  GEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDA 712

Query: 2338 GIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCPCCYGPLECP 2397
            G  G  G+ G PG+ G  G+ G  G  GPKG+RGD+  + A     KD      GP+  P
Sbjct: 713  GAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPP 772



 Score =  268 bits (686), Expect = 5e-71
 Identities = 164/433 (37%), Positives = 195/433 (45%), Gaps = 106/433 (24%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G+ G  GP+G  GP G PG++G  G  G  G PGERGPPG  G +G  G  G  G+KG R
Sbjct: 209  GEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHR 268

Query: 2098 GF---------------------PGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGR- 2135
            GF                     PGE G  G++G  GL GE G  G PG +G +GN G  
Sbjct: 269  GFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGAT 328

Query: 2136 -----------------------RGDKGPRGEKGERGDVGIRGDPGNPGQ-----DSQER 2167
                                   +G+ GP+G +G  G  G+RG+PG PG       +   
Sbjct: 329  GAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNP 388

Query: 2168 GPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTR 2227
            G  G+ G  G  G PG  G PG PG  G +G  G  GPPG KGN G PG PG +G+ G +
Sbjct: 389  GADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAK 448

Query: 2228 GAQGP------------------------------------------------AGPAGPP 2239
            G  GP                                                AGP GP 
Sbjct: 449  GEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPA 508

Query: 2240 GLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRD 2299
            G  G  G +GP+GS G AG PGE G  G  G  G PG PGP    G  GP G  G DGR 
Sbjct: 509  GERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPD---GKTGPPGPAGQDGRP 565

Query: 2300 GVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPG 2359
              G  G  G +G+ G  G+PGPKG  GEP   G  G +G+ G  G  GP G  G+ G  G
Sbjct: 566  --GPPGPPGARGQAGVMGFPGPKGAAGEP---GKAGERGVPGPPGAVGPAGKDGEAGAQG 620

Query: 2360 YPGPAGPKGNRGD 2372
             PGPAGP G RG+
Sbjct: 621  PPGPAGPAGERGE 633



 Score =  265 bits (676), Expect = 7e-70
 Identities = 163/370 (44%), Positives = 188/370 (50%), Gaps = 35/370 (9%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS- 2096
            G  G +GP G  GPKG  GE G  G  GD G  GE GP GV G  G  G  G+RG +G  
Sbjct: 416  GPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEP 475

Query: 2097 --RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154
               G PG  GE G  G  G  G DG  G  G +GE+G+PG  G KG  GE G  G+ G+ 
Sbjct: 476  GPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLP 535

Query: 2155 GDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP------PGA 2208
            G  G  G      GP G+TG  GP G  GR G PG PG  G+ G  G  GP      PG 
Sbjct: 536  GAKGLTGSPGSP-GPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGK 594

Query: 2209 KGNKGGPGQPGF---EGEQGTRGAQGPAGPAGPPGLIGEQGISGP---RGSGGAAGAPGE 2262
             G +G PG PG     G+ G  GAQGP GPAGP G  GEQG +G    +G  G AG PGE
Sbjct: 595  AGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGE 654

Query: 2263 RGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-------GSEGRRGKKGERGF 2315
             G+ G  G  G+ G PGP G  G RG  GE G  G  G        G+ G  G KG+ G 
Sbjct: 655  AGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGA 714

Query: 2316 PGYPGPKGNPG---EPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGY---------PGP 2363
            PG PG +G PG    PG  G  G  G +G RG++GP G  G  G  G          PGP
Sbjct: 715  PGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGP 774

Query: 2364 AGPKGNRGDS 2373
            AG  G++G+S
Sbjct: 775  AGAPGDKGES 784



 Score =  264 bits (675), Expect = 9e-70
 Identities = 158/378 (41%), Positives = 185/378 (48%), Gaps = 44/378 (11%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGV---NGTQGFQGCPGQRGV 2093
            +G +G  G  G  G  G+PG  G  G PG  G  G+ GPPG    +G  G  G PG RG 
Sbjct: 517  AGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQ 576

Query: 2094 KGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI 2153
             G  GFPG KG  GE G  G  G  G  G  G +G+ G  G +G  GP G  GERG+ G 
Sbjct: 577  AGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGP 636

Query: 2154 RGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRR---GPP---- 2206
             G PG  G      GP GE G  G  GVPG  G PG  G  G+ G  G R   GPP    
Sbjct: 637  AGSPGFQGLPG-PAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAG 695

Query: 2207 -----------GAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGG 2255
                       GAKG+ G PG PG +G  G +G  G  G AG PG  G++G +GP+G+ G
Sbjct: 696  PRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADG 755

Query: 2256 AAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG--------------- 2300
            + G  G RG TGP+G  G  G PG KG  G  GP G TG  G  G               
Sbjct: 756  SPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAG 815

Query: 2301 -VGSEGRRGKKGE------RGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVG 2353
              G++G+ G KGE      +G  G PGP G  G PG  G  G  G +G RG++GPPG  G
Sbjct: 816  PPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATG 875

Query: 2354 QKGDPGYPGPAGPKGNRG 2371
              G  G  GP GP GN G
Sbjct: 876  FPGAAGRVGPPGPSGNAG 893



 Score =  260 bits (664), Expect = 2e-68
 Identities = 157/371 (42%), Positives = 175/371 (47%), Gaps = 49/371 (13%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGV------------------- 2078
            G +GD GP G  GP G PG DG  G PG  G PG  GPPG                    
Sbjct: 112  GPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKS 171

Query: 2079 ------------NGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGS 2126
                        +G +G  G PG  G +G +G PGE GE G  G  G  G  G  G  G 
Sbjct: 172  TGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGD 231

Query: 2127 SGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDG 2186
             GE G PGR G++GP G +G RG  G  G PG  G     RG  G  G  G  G  G  G
Sbjct: 232  DGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGH----RGFSGLDGAKGDAGPAGPKG 287

Query: 2187 VPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQG 2246
             PG PGE G  G  G RG PG +G  G PG  G  G  G  GA GP GP GP G     G
Sbjct: 288  EPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAG---PPG 344

Query: 2247 ISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGR 2306
              G  G+ G AG  G RG  GP G +GEPG PGP G     GP G  G DG+   G++G 
Sbjct: 345  FPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGA---AGPAGNPGADGQP--GAKGA 399

Query: 2307 RGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDP------GY 2360
             G  G  G PG+PG +G  G  G  G  GPKG  G  G  G  G  G KG+P      G 
Sbjct: 400  NGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGP 459

Query: 2361 PGPAGPKGNRG 2371
            PGPAG +G RG
Sbjct: 460  PGPAGEEGKRG 470



 Score =  257 bits (656), Expect = 1e-67
 Identities = 143/329 (43%), Positives = 167/329 (50%), Gaps = 24/329 (7%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G  G+ GP G  GP G  G  G RG  G  G PGE GPPG  G  G +G PG  G  G+ 
Sbjct: 887  GPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAP 946

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157
            G PG +G  G+ G+ GL G+ G++G PG  G  G PG++G  G  GE+G  G +G  G  
Sbjct: 947  GTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLA 1006

Query: 2158 GNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQ 2217
            G PG+  +E  P  E       G PGRDG PG  G+ G+ G  G  G PGA G  G  G 
Sbjct: 1007 GPPGESGREGAPGAE-------GSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGP 1059

Query: 2218 PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGE 2277
             G  G++G  G  GPAGP GP G  G  G  GPRG  G  G  G+RG  G  G  G  G 
Sbjct: 1060 AGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGP 1119

Query: 2278 PGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPK 2337
            PGP G  G +GP G +G  G  G                  PG  G PG+ GLNG  GP 
Sbjct: 1120 PGPPGSPGEQGPSGASGPAGPRGP-----------------PGSAGAPGKDGLNGLPGPI 1162

Query: 2338 GIRGRRGNSGPPGIVGQKGDPGYPGPAGP 2366
            G  G RG +G  G VG  G PG PGP GP
Sbjct: 1163 GPPGPRGRTGDAGPVGPPGPPGPPGPPGP 1191



 Score =  221 bits (562), Expect = 1e-56
 Identities = 140/321 (43%), Positives = 161/321 (50%), Gaps = 58/321 (18%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPG---DEGGPGERGPPGVNGTQGFQGCPGQRGV 2093
            +G+ G +GP G  GP G PGE G  G PG   ++G PG  GP G  GT G QG  GQRGV
Sbjct: 901  AGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGV 960

Query: 2094 KGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI 2153
             G    PG++GE G  GL G  GE G +G  G+SGE+G PG  G  G  G  GE G  G 
Sbjct: 961  VG---LPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGA 1017

Query: 2154 RGDPGNPGQDSQE--RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA--- 2208
             G  G+PG+D     +G +GETG  GP G PG  G PG  G  GK+G  G  GP G    
Sbjct: 1018 PGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGP 1077

Query: 2209 ---------------KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISG---- 2249
                           +G+KG  G+ G  G +G RG  G  GP GPPG  GEQG SG    
Sbjct: 1078 VGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGP 1137

Query: 2250 --PRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRR 2307
              PRG  G+AGAPG+ G           G PGP   IG  GPRG TGD            
Sbjct: 1138 AGPRGPPGSAGAPGKDGLN---------GLPGP---IGPPGPRGRTGD------------ 1173

Query: 2308 GKKGERGFPGYPGPKGNPGEP 2328
               G  G PG PGP G PG P
Sbjct: 1174 --AGPVGPPGPPGPPGPPGPP 1192



 Score =  196 bits (498), Expect = 3e-49
 Identities = 131/331 (39%), Positives = 152/331 (45%), Gaps = 34/331 (10%)

Query: 2058 DGYRGYPGDEGGPGERGPPGVNGTQG--FQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLD 2115
            D  +  PG E   GE  P   +G++    Q   G  G KG  G  G +G  G  G DG+ 
Sbjct: 76   DETKNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIP 135

Query: 2116 GEDGDKGLPGSSGEKGNPGRRGDKGPRGEKG--ERGDVGIRGDPGNPGQDSQERGPKGET 2173
            G+ G  G PG  G  G PG  G+  P+   G  E+   GI   PG  G      GP+G  
Sbjct: 136  GQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGI-SVPGPMGPS----GPRGLP 190

Query: 2174 GDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPA 2233
            G  G  G  G  G PG PGE G +G  G RGPPG  G  G  G+ G  G  G RG  GP 
Sbjct: 191  GPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQ 250

Query: 2234 GPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPK---------GGI 2284
            G  G PG  G  G+ G RG  G  GA            KG+ G  GPK         G  
Sbjct: 251  GARGLPGTAGLPGMKGHRGFSGLDGA------------KGDAGPAGPKGEPGSPGENGAP 298

Query: 2285 GNRGPRGETGDDGRDG----VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIR 2340
            G  GPRG  G+ GR G     G+ G  G  G  G PG  GP G PG PG  G  G  G +
Sbjct: 299  GQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQ 358

Query: 2341 GRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
            G RG+ GP G+ G+ G PG  G AGP GN G
Sbjct: 359  GPRGSEGPQGVRGEPGPPGPAGAAGPAGNPG 389



 Score =  160 bits (405), Expect = 2e-38
 Identities = 96/225 (42%), Positives = 109/225 (48%), Gaps = 19/225 (8%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRG 2092
            P   SG+RG  GP+G  G  G PGE G  G PG EG PG  G PG  G +G  G  G  G
Sbjct: 987  PSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPG 1046

Query: 2093 VKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVG 2152
              G+ G PG  G  G+ G  G  G  G  G  G  G +G  G +G +G +GE GE+GD  
Sbjct: 1047 APGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGD-- 1104

Query: 2153 IRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPP---GAK 2209
                          RG KG  G  G  G PG  G PG  G +G +G  G RGPP   GA 
Sbjct: 1105 --------------RGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAP 1150

Query: 2210 GNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSG 2254
            G  G  G PG  G  G RG  G AGP GPPG  G  G  GP  +G
Sbjct: 1151 GKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAG 1195



 Score =  151 bits (381), Expect = 1e-35
 Identities = 92/227 (40%), Positives = 106/227 (46%), Gaps = 27/227 (11%)

Query: 2169 PKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRG 2228
            P+GE   + P G       P     TG  G  G  GP G +G  G PG+ G  G+ G  G
Sbjct: 87   PEGECCPVCPDGSES----PTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPG 142

Query: 2229 AQGPAGPAGPPGLIGE----------------------QGISGPRGSGGAAGAPGERGRT 2266
              GP GP GPPGL G                        G SGPRG  G  GAPG +G  
Sbjct: 143  PPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQ 202

Query: 2267 GPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNP 2325
            GP G  GEPG  GP G  G  GP G+ GDDG  G  G  G RG  G +G  G PG  G P
Sbjct: 203  GPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLP 262

Query: 2326 GEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
            G  G  G +G  G +G  G +GP G  G  G+ G PG  GP+G  G+
Sbjct: 263  GMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGE 309



 Score = 79.0 bits (193), Expect = 7e-14
 Identities = 49/131 (37%), Positives = 54/131 (41%), Gaps = 39/131 (29%)

Query: 2276 GEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGT-- 2333
            G  GPKG  G RGPRG  G  GRDG+         G+ G PG PGP G PG PGL G   
Sbjct: 109  GVEGPKGDTGPRGPRGPAGPPGRDGI--------PGQPGLPGPPGPPGPPGPPGLGGNFA 160

Query: 2334 -----------------------------TGPKGIRGRRGNSGPPGIVGQKGDPGYPGPA 2364
                                          GP G  G +G  GPPG  G+ G  G  GP 
Sbjct: 161  PQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPR 220

Query: 2365 GPKGNRGDSID 2375
            GP G  G + D
Sbjct: 221  GPPGPPGKNGD 231



 Score = 47.0 bits (110), Expect = 3e-04
 Identities = 26/60 (43%), Positives = 29/60 (48%), Gaps = 6/60 (10%)

Query: 2317 GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQ 2376
            G  GPKG+       G  GP+G  G  G  G PG  G  G PG PGP GP G  G+   Q
Sbjct: 109  GVEGPKGD------TGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQ 162


>gi|154759255 collagen, type XXVIII precursor [Homo sapiens]
          Length = 1125

 Score =  301 bits (772), Expect = 5e-81
 Identities = 203/531 (38%), Positives = 275/531 (51%), Gaps = 65/531 (12%)

Query: 2038 GQRGDRGPIGSIGPKGIPG--EDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKG 2095
            G++GD GP+G  GP GIPG    G +G  G  G PG +GP G  G  G +G  GQ G  G
Sbjct: 432  GEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTG 490

Query: 2096 SRG-----FPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGP--RGEKGER 2148
             RG       G KGE G IGL G  G  G+ G  G  GE G PG RG +GP  +G+ G +
Sbjct: 491  PRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPK 550

Query: 2149 GDVGIRGDPGNPGQDSQE--RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPP 2206
            GD G +G  GN GQ       GPKGE G +GP G+PG   +PG               PP
Sbjct: 551  GDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTS-IPG---------------PP 594

Query: 2207 GAKGNKGGPGQPGFEGE-----QGTRGAQGPAGPAGPPGLIGE--QGISGPRGSGGAAGA 2259
            G KG++GGPG PGF+GE     +G +G QGP GP G PGL G+   G+ GPRG  G  G 
Sbjct: 595  GPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGP 654

Query: 2260 PGERGRTGPLGRKGEPGEPGPKG-----GIGNRGPRGETGDDGRDGVGSE---GRRGKKG 2311
             G RG  G  G KGEPG  GP G     G+G +GP+G+TG  G  G       G +G KG
Sbjct: 655  MGLRG-VGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKG 713

Query: 2312 ERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
            E+G  G+PGPKG  G    +G  G KG  G RG+ G  G  G+ G+PG PG  G +G +G
Sbjct: 714  EQGPQGFPGPKGTMG----HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKG 769

Query: 2372 D-SIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVN 2430
            D  + +  +I+ I + C C  GP +C   P EL F +D+SE V  + F  +++ V ++ +
Sbjct: 770  DLGLTKEEIIKLITEICGC--GP-KCKETPLELVFVIDSSESVGPENFQIIKNFVKTMAD 826

Query: 2431 DLTIAESNCPRGARVAVVTYNNEVTTEIRFADSKRKSVLLDKIKNLQVALTSKQQSLETA 2490
             + +  +     AR+ ++ Y+++V           K      + N+Q       +   TA
Sbjct: 827  RVALDLAT----ARIGIINYSHKVEKVANLKQFSSKDDFKLAVDNMQYL----GEGTYTA 878

Query: 2491 MSFVARN-TFKRVRNGFLMRKVAVFFSN--TPTRASPQLREAVLKLSDAGI 2538
             +  A N  F+  R G  ++KVA+  ++  T +R   +L E V   SD  +
Sbjct: 879  TALQAANDMFEDARPG--VKKVALVITDGQTDSRDKEKLTEVVKNASDTNV 927



 Score =  269 bits (688), Expect = 3e-71
 Identities = 214/601 (35%), Positives = 286/601 (47%), Gaps = 82/601 (13%)

Query: 1835 CNLDVILGFDGSRDQNV--FVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVAN 1892
            C +D++   D S    +  F  QK F   VD++ ++I Q+     + GRS    + + A 
Sbjct: 45   CFIDIVFIVDSSESSKIALFDKQKDF---VDSLSDKIFQL-----TPGRSLEYDIKLAAL 96

Query: 1893 TPSGPVEAF-------DFDEYQPEMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSV 1945
              S  V+         D   ++ ++  K  N+  Q  +     +    L K R+   D V
Sbjct: 97   QFSSSVQIDPPFSSWKDLQTFKQKV--KSMNLIGQGTFSYYAISNATRLLK-REGRKDGV 153

Query: 1946 KVVIHFTDGADGDL-ADLHRASENLRQEGVRALILVGLERVVNLERLMHLEFGRGFMYDR 2004
            KVV+  TDG D     D+   SE+ R  G+ + I + L  VVN  +L  +    G     
Sbjct: 154  KVVLLMTDGIDHPKNPDVQSISEDARISGI-SFITIALSTVVNEAKLRLIS---GDSSSE 209

Query: 2005 P-LRLNLLDLDYELAEQLDNIAEKACCGVPCKCS-GQRGDRGPIGSIGPKGIPGEDGYRG 2062
            P L L+   L  ++ ++LD + EK C    C+C  G  GD GP G+ G  GI GE G +G
Sbjct: 210  PTLLLSDPTLVDKIQDRLDILFEKKCERKICECEKGDPGDPGPPGTHGNPGIKGERGPKG 269

Query: 2063 YPGD--EGGPGERGP---PGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGE 2117
             PG+  +G  GERGP   PG  G +G +G  G+ G+KG +G PG  G  G  G+ G+ G 
Sbjct: 270  NPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGP 329

Query: 2118 DGDKGLPGSSGEKGNPGRRGDKGPRG-----EKGERGDVGIRGDPGNPGQDSQERGPKGE 2172
             GD G  G  G KG PG  G  G  G     ++G +G+ G  G PG PG      G  G+
Sbjct: 330  PGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIGV--GEPGQ 387

Query: 2173 TGDLGPMGVPGRDGVPGG--PGETGKNGGFGRRGPPGA-----KGNKG-----GPGQP-- 2218
             G  GP GVPG  G+PG   PG  G+ G  G  GP G      KG KG     GP  P  
Sbjct: 388  PGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMG 447

Query: 2219 ----GFEGEQGTRGAQGPAGPAGPPGL--------IGEQGISGPRGSGGAAGAPGERGRT 2266
                G +GEQG +G  GP GP GP G         +G+ G +GPRG  G  G  G +G  
Sbjct: 448  IPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEP 506

Query: 2267 GPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV------------GSEGRRGKKGERG 2314
            G +G  G+PG PG  G  G +G  G  G  G +G             G +G +G +G+RG
Sbjct: 507  GSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRG 566

Query: 2315 FPGYPGPKGNPGEPGLNGTTGPK--GIRGRRGNSGPPGIVGQKGDPGYP--GPAGPKGNR 2370
             PG  GPKG PG  G  G  G    G  G +G+ G PGI G KG+PG    GP G +G R
Sbjct: 567  LPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPR 626

Query: 2371 G 2371
            G
Sbjct: 627  G 627



 Score =  153 bits (386), Expect = 3e-36
 Identities = 89/203 (43%), Positives = 106/203 (52%), Gaps = 15/203 (7%)

Query: 2172 ETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQG 2231
            E GD G  G PG  G PG  GE G  G  G     G  G +G  G PG++G++G RG  G
Sbjct: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPGYKGDKGERGECG 301

Query: 2232 PAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRG 2291
              G  G  G  G  G  GPRG  G  G PG+ G  G  G KGEPG PGP G         
Sbjct: 302  KPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGS-------- 353

Query: 2292 ETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGI 2351
                 G  G+G +G +G++G+ G PG PGP G  GEPG  G  GP+G+ G RG  G  G 
Sbjct: 354  ----PGAPGIGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPG-EGF 407

Query: 2352 VGQKGDPGYPGPAGPKGNRGDSI 2374
             G KG+ G  GP GP+G +G SI
Sbjct: 408  PGPKGEKGSEGPTGPQGLQGLSI 430



 Score = 96.7 bits (239), Expect = 3e-19
 Identities = 64/144 (44%), Positives = 80/144 (55%), Gaps = 15/144 (10%)

Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQ 2090
            GVP    G RG  GP G +G +G+ G+ G +G PG  G PG  GP GV GTQG +G  GQ
Sbjct: 641  GVP----GPRGLPGPPGPMGLRGV-GDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTGQ 694

Query: 2091 RGVKGSRGFPGE-----KGEVGEIGLDGLDGEDGDKGLPGSSGE---KGNPGRRGDKGPR 2142
            +G+ G  G PG      KGE G  G  G  G  G  GLPG  GE   +G+ G++GDKG  
Sbjct: 695  KGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMGH-GLPGQKGEHGERGDVGKKGDKGEI 753

Query: 2143 GEKGERGDVGIRGDPGNPGQDSQE 2166
            GE G  G  G++G  G+ G   +E
Sbjct: 754  GEPGSPGKQGLQGPKGDLGLTKEE 777



 Score = 72.8 bits (177), Expect = 5e-12
 Identities = 30/79 (37%), Positives = 47/79 (59%), Gaps = 1/79 (1%)

Query: 3084 PQPARSASSSTINLMVSTEPLALTETDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYG 3143
            P    S +++T   ++ST P+   E   C      G C +++++WYYD    SCARFW+ 
Sbjct: 1045 PATTSSEATTTPRPLLST-PVDGAEDPRCLEALKPGNCGEYVVRWYYDKQVNSCARFWFS 1103

Query: 3144 GCGGNENKFGSQKECEKVC 3162
            GC G+ N+F S+KEC++ C
Sbjct: 1104 GCNGSGNRFNSEKECQETC 1122



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 53/203 (26%), Positives = 90/203 (44%), Gaps = 24/203 (11%)

Query: 1411 LTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGP 1470
            LT E+I KL+       P  +    ++VF+IDSSE V P+ F  I++FV  +  R+ +  
Sbjct: 773  LTKEEIIKLITEICGCGPKCKETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVALDL 832

Query: 1471 SKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVK 1530
            +  R+G++ +S+ V     LK + S+     A+  ++  G     T  AL+         
Sbjct: 833  ATARIGIINYSHKVEKVANLKQFSSKDDFKLAVDNMQYLGEGTY-TATALQ--------- 882

Query: 1531 SAGSRIEDGVP----QHLVLVLGGKSQDDVSRFAQVIRSSG-----IVSLGVGDRN---- 1577
            +A    ED  P      LV+  G     D  +  +V++++      I  +GV  +N    
Sbjct: 883  AANDMFEDARPGVKKVALVITDGQTDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNF 942

Query: 1578 -IDRTELQTITNDPRLVFTVREF 1599
             I   E+  I  DP  V+   +F
Sbjct: 943  EIFHKEMNLIATDPEHVYQFDDF 965



 Score = 58.5 bits (140), Expect = 1e-07
 Identities = 48/198 (24%), Positives = 89/198 (44%), Gaps = 19/198 (9%)

Query: 631 PEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTE 690
           P+      +++F++D S +VG  NF  +++FV  + + + +     R+G++ +S      
Sbjct: 790 PKCKETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGIINYSHKVEKV 849

Query: 691 FSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLL 750
            +L  + +K D    +  +Q   G G  T +AL    AN   E      R  V ++ L++
Sbjct: 850 ANLKQFSSKDDFKLAVDNMQYL-GEGTYTATALQ--AANDMFEDA----RPGVKKVALVI 902

Query: 751 TAGQSE----DSYLQAANALTRAGILTFCVGASQAN-------KAELEQIAFNPSLVYLM 799
           T GQ++    +   +     +   +  F +G  + N         E+  IA +P  VY  
Sbjct: 903 TDGQTDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIATDPEHVYQF 962

Query: 800 DDFSSL-PALPQQLIQPL 816
           DDF +L   L Q+L Q +
Sbjct: 963 DDFFTLQDTLKQKLFQKI 980



 Score = 58.2 bits (139), Expect = 1e-07
 Identities = 43/180 (23%), Positives = 84/180 (46%), Gaps = 17/180 (9%)

Query: 39  DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRT 98
           +++F++DSS ++G E+FQ+++ F+  +   +A+        ++ ++        L  + +
Sbjct: 798 ELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGIINYSHKVEKVANLKQFSS 857

Query: 99  KQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGH--SKD 156
           K +    + NM Y+G    T   L+              A  GV +V +V+TDG   S+D
Sbjct: 858 KDDFKLAVDNMQYLGEGTYTATALQ------AANDMFEDARPGVKKVALVITDGQTDSRD 911

Query: 157 GLALPSAELKSADVNV--FAIGVEDADEGALKEIASEPLNM------HMFNLENFTSLHD 208
              L      ++D NV  F IGV   ++    EI  + +N+      H++  ++F +L D
Sbjct: 912 KEKLTEVVKNASDTNVEIFVIGVVKKNDPNF-EIFHKEMNLIATDPEHVYQFDDFFTLQD 970



 Score = 52.8 bits (125), Expect = 5e-06
 Identities = 58/236 (24%), Positives = 104/236 (44%), Gaps = 25/236 (10%)

Query: 1208 LTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGF 1266
            LT+EE+ +L   +            ++VF+ID S+S GPE FQ ++  ++ + D + +  
Sbjct: 773  LTKEEIIKLITEICGCGPKCKETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVALDL 832

Query: 1267 DTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFK- 1325
             T R+ +I +S   +    L   SSKD+ + AV  ++   G       AL+  + ++F+ 
Sbjct: 833  ATARIGIINYSHKVEKVANLKQFSSKDDFKLAVDNMQYL-GEGTYTATALQ-AANDMFED 890

Query: 1326 -RPLGSRIEEGVPQFLVLISSGKSDD-----------EVDDPAVELKQFGVAPFTIAR-N 1372
             RP       GV +  ++I+ G++D               D  VE+   GV         
Sbjct: 891  ARP-------GVKKVALVITDGQTDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFE 943

Query: 1373 ADQEELVKISLSPEYVFSVSTFREL-PSLEQKLLTPITTLTSEQIQKLLASTRYPP 1427
               +E+  I+  PE+V+    F  L  +L+QKL   I       + ++  S+   P
Sbjct: 944  IFHKEMNLIATDPEHVYQFDDFFTLQDTLKQKLFQKICEDFDSYLVQIFGSSSPQP 999



 Score = 48.5 bits (114), Expect = 1e-04
 Identities = 33/143 (23%), Positives = 69/143 (48%), Gaps = 11/143 (7%)

Query: 445 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 504
           ++VF++D S ++G  NF  I++F+  +  R+ +     ++ +  Y+  V          +
Sbjct: 798 ELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGIINYSHKVEKVANLKQFSS 857

Query: 505 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGG----K 560
           K +   AV  M+ L G   YT +AL    N++F       A  G+ K+ ++IT G    +
Sbjct: 858 KDDFKLAVDNMQYL-GEGTYTATALQ-AANDMFED-----ARPGVKKVALVITDGQTDSR 910

Query: 561 SLDEISQPAQELKRSSIMAFAIG 583
             +++++  +    +++  F IG
Sbjct: 911 DKEKLTEVVKNASDTNVEIFVIG 933



 Score = 46.6 bits (109), Expect = 4e-04
 Identities = 46/190 (24%), Positives = 88/190 (46%), Gaps = 19/190 (10%)

Query: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 301
           +++F+ID S + G  NF +I +F+  + +++ +     R+G++ +S +   + +L  +S+
Sbjct: 798 ELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGIINYSHKVEKVANLKQFSS 857

Query: 302 KAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDE 361
           K     AV  + +  GE      AL     + F  A       GV +V ++I+ G +   
Sbjct: 858 KDDFKLAVDNMQYL-GEGTYTATALQ-AANDMFEDA-----RPGVKKVALVITDGQTDSR 910

Query: 362 IRYGVV-ALKQAS-----VFSFGLGAQAASRAELQH-----IATDDNLVFTVPEFRSFGD 410
            +  +   +K AS     +F  G+  +     E+ H     IATD   V+   +F +  D
Sbjct: 911 DKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIATDPEHVYQFDDFFTLQD 970

Query: 411 -LQEKLLPYI 419
            L++KL   I
Sbjct: 971 TLKQKLFQKI 980



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 54/243 (22%), Positives = 102/243 (41%), Gaps = 20/243 (8%)

Query: 1002 IGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVR-SGFPLLKEFVQRVVESLDV 1060
            +G    +I+ L+  +    P       ++VF++D SE V    F ++K FV+ + + + +
Sbjct: 771  LGLTKEEIIKLITEICGCGPKCKETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVAL 830

Query: 1061 GQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNIL 1120
                 R+ ++ YS +      L  + +K D   AV  +  LG  T  T  AL+    N +
Sbjct: 831  DLATARIGIINYSHKVEKVANLKQFSSKDDFKLAVDNMQYLGEGT-YTATALQ--AANDM 887

Query: 1121 VSSAGSRITEGVPQLLIVLTADRSGD-DVRNPSVVVKRGGAVPIGIGI--------GNAD 1171
               A      GV ++ +V+T  ++   D    + VVK      + I +         N +
Sbjct: 888  FEDA----RPGVKKVALVITDGQTDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFE 943

Query: 1172 I--TEMQTISFIPDFAVAIPTFRQL-GTVQQVISERVTQLTREELSRLQPVLQPLPSPGV 1228
            I   EM  I+  P+       F  L  T++Q + +++ +     L ++     P P  G+
Sbjct: 944  IFHKEMNLIATDPEHVYQFDDFFTLQDTLKQKLFQKICEDFDSYLVQIFGSSSPQPGFGM 1003

Query: 1229 GGK 1231
             G+
Sbjct: 1004 SGE 1006



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 36/169 (21%), Positives = 73/169 (43%), Gaps = 17/169 (10%)

Query: 2613 GSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPS 2672
            GS   ID+ FI+DS+E++ +  F++ K ++  L  ++      ++ ++  ++A +Q + S
Sbjct: 42   GSICFIDIVFIVDSSESSKIALFDKQKDFVDSLSDKIFQLTPGRSLEYDIKLAALQFSSS 101

Query: 2673 ESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFE--SA 2730
              +D    PP      L  +  K K ++ + +G               Y I N       
Sbjct: 102  VQID----PPFSSWKDLQTFKQKVKSMNLIGQGTFSY-----------YAISNATRLLKR 146

Query: 2731 PNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVN 2779
               +D   VVL++T  +   +  + Q +   A+  G  F+ + +   VN
Sbjct: 147  EGRKDGVKVVLLMTDGIDHPKNPDVQSISEDARISGISFITIALSTVVN 195



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 36/144 (25%), Positives = 64/144 (44%), Gaps = 11/144 (7%)

Query: 1639 DIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFST 1698
            ++VF++D S +   ++FQ +  FV  + D V  D  + ++G++ Y+        LK FS+
Sbjct: 798  ELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGIINYSHKVEKVANLKQFSS 857

Query: 1699 KRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGG----K 1754
            K     A++ + Y G     T         N    +A       V ++A VIT G    +
Sbjct: 858  KDDFKLAVDNMQYLG---EGTYTATALQAANDMFEDA----RPGVKKVALVITDGQTDSR 910

Query: 1755 SVEDAQDVSLALTQRGVKVFAVGV 1778
              E   +V    +   V++F +GV
Sbjct: 911  DKEKLTEVVKNASDTNVEIFVIGV 934



 Score = 33.9 bits (76), Expect = 2.6
 Identities = 49/223 (21%), Positives = 90/223 (40%), Gaps = 28/223 (12%)

Query: 1436 DIVFLIDSSEGVRPDGFAHIRDFVSRI---VRRLNIGPS---KVRVGVVQFSNDVFPEFY 1489
            DIVF++DSSE  +   F   +DFV  +   + +L  G S    +++  +QFS+ V  +  
Sbjct: 48   DIVFIVDSSESSKIALFDKQKDFVDSLSDKIFQLTPGRSLEYDIKLAALQFSSSVQIDPP 107

Query: 1490 LKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLG 1549
              +++        ++ + L G    +   A+    R   +K  G +  DGV   L++  G
Sbjct: 108  FSSWKDLQTFKQKVKSMNLIGQGTFSY-YAISNATR--LLKREGRK--DGVKVVLLMTDG 162

Query: 1550 --GKSQDDVSRFAQVIRSSGIVSLGVGDRNI------------DRTELQTITNDPRLVFT 1595
                   DV   ++  R SGI  + +    +              +E   + +DP LV  
Sbjct: 163  IDHPKNPDVQSISEDARISGISFITIALSTVVNEAKLRLISGDSSSEPTLLLSDPTLVDK 222

Query: 1596 VREFREL---PNIEERIMNSFGPSAATPAPPGVDTPPPSRPEK 1635
            +++  ++      E +I          P PPG    P  + E+
Sbjct: 223  IQDRLDILFEKKCERKICECEKGDPGDPGPPGTHGNPGIKGER 265


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  298 bits (762), Expect = 7e-80
 Identities = 176/397 (44%), Positives = 202/397 (50%), Gaps = 63/397 (15%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G  G++GP+G  G  G+PG DG  G+PG EG PGE+G  G  G QG  G PG RGVKG+ 
Sbjct: 739  GPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGAD 798

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEK------------ 2145
            G  G KG  GE G DG  G  GD G+ G  GE G PG RG+ GP G K            
Sbjct: 799  GIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPL 858

Query: 2146 ---GERGDVGI------------------------------RGDPGNPGQDSQ------- 2165
               GE+G +G+                              RG PG PG   Q       
Sbjct: 859  GPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPR 918

Query: 2166 -ERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQ---PGFE 2221
             ERGP+G TG  GP G  G DG  G PGE G NG  G  G PG KG  G PG+   PG  
Sbjct: 919  GERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHP 978

Query: 2222 GEQGTRGAQGPAGPAGPPGLIGEQGIS------GPRGSGGAAGAPGERGRTGPLGRKGEP 2275
            G++G  G QG  GP GPPG++G QG +      G RG  G  G PGE+G  G  G++G  
Sbjct: 979  GQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTK 1038

Query: 2276 GEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTT 2334
            G+PGP G  G  GP G  G  G  G+ G  G  G KG  G PG PGP G+PGE G  G  
Sbjct: 1039 GDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAA 1098

Query: 2335 GPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
            GP GI GR G  GPPG  G+KG PG  GP GP G  G
Sbjct: 1099 GPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1135



 Score =  288 bits (737), Expect = 6e-77
 Identities = 166/376 (44%), Positives = 195/376 (51%), Gaps = 47/376 (12%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPG------DEGGPGERGPPGVNGTQGFQGCPGQR 2091
            G  G +GPIG  GP G  GE G RG  G      DEG  G  GPPG  G QG  G PG++
Sbjct: 1180 GPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEK 1239

Query: 2092 GVKGSRGF------PGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKG----- 2140
            G  G  G       PG +G  G  G DG  G  G  G PG+ GEKG PG  G+ G     
Sbjct: 1240 GETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEG 1299

Query: 2141 ----PRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGK 2196
                P+GE+GE+G+ G  G  G PG       PKG  GD GP G PG  G PG PG  G+
Sbjct: 1300 GPPGPKGERGEKGESGPSGAAGPPG-------PKGPPGDDGPKGSPGPVGFPGDPGPPGE 1352

Query: 2197 NGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGA 2256
             G  G+ GPPG KG+ G PGQ G  G  G  G  GP G  GPPG  G +G  G +G+ G 
Sbjct: 1353 PGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGE 1412

Query: 2257 AGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-------------VGS 2303
            AG  G  G+TGP+G +G PG+PGP G  G  GP GE G  G  G              G 
Sbjct: 1413 AGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGL 1472

Query: 2304 EGRRGKKGERGFPGY------PGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGD 2357
            +G  G KGE+G PG       PG +G  G+ GL G  G  G +G +G +GP G +G  G 
Sbjct: 1473 KGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGP 1532

Query: 2358 PGYPGPAGPKGNRGDS 2373
            PG PGP GPKG +G S
Sbjct: 1533 PGLPGPPGPKGAKGSS 1548



 Score =  287 bits (735), Expect = 1e-76
 Identities = 179/434 (41%), Positives = 212/434 (48%), Gaps = 99/434 (22%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPG---DEGGPGERGPPGVNGTQGFQGCPGQRGV 2093
            +G  G+RGP G+ GP GIPG  G +G PG   ++G PGE+GP G  G  G QG  G  G 
Sbjct: 1086 AGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGP 1145

Query: 2094 KGSRGFPGEKGEVGEIGLDGLDGEDGDK---------------GLPGSSGEKGNP----- 2133
             G  G PGE G+ GEIG  G  G  GDK               G PG SG  G P     
Sbjct: 1146 AGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQ 1205

Query: 2134 ----GRRGDKGPRGEKGERGDVGIRGDPGNPGQ-----DSQERGPKGETGDLGPMGVPGR 2184
                G++GD+GPRG  G  G VG++G PG PG+     D  + GP G  G  GP G PG 
Sbjct: 1206 QGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGA 1265

Query: 2185 DGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQ---PGFEGEQGTRGAQGPAGPAGPPGL 2241
            DG  G PG  G  G  G +G PG  G  G PG+   PG +GE+G +G  GP+G AGPPG 
Sbjct: 1266 DGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGP 1325

Query: 2242 IGEQGISGPRGSGGAAGAPGE---RGRTGPLGRKGEP------------------GEPGP 2280
             G  G  GP+GS G  G PG+    G  GP G+ G P                  GEPGP
Sbjct: 1326 KGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGP 1385

Query: 2281 KGGIGNRGPRGETGDDGRDG-------------------VGSEGRRGKK----------- 2310
             G  G RGP G  G +GR G                   +G +G  GK            
Sbjct: 1386 SGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGP 1445

Query: 2311 -GERGFPGYPGPKGNPGE------PGLNGTTGPKGIRGRR---GNSGPPGIVGQKGDPGY 2360
             GE+G PG PGP G PG       PGL G +GPKG +G     G  GPPG  G+KGD G 
Sbjct: 1446 VGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGL 1505

Query: 2361 PGP---AGPKGNRG 2371
            PGP   +GPKG +G
Sbjct: 1506 PGPQGSSGPKGEQG 1519



 Score =  278 bits (710), Expect = 8e-74
 Identities = 164/356 (46%), Positives = 186/356 (52%), Gaps = 29/356 (8%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G RG  GP G +G +G+PG  G +G  GD G  G  GPPG  G  G  G  G +G  G  
Sbjct: 1216 GPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGI 1275

Query: 2098 GFPG---EKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD---- 2150
            G PG   EKGE GE G  GL GE G  G  G  GEKG  G  G  GP G KG  GD    
Sbjct: 1276 GNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPK 1335

Query: 2151 -----VGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP 2205
                 VG  GDPG PG+     G  G  GD G  G PG+ G PG  GE G +G  G+RGP
Sbjct: 1336 GSPGPVGFPGDPGPPGEPGPA-GQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGP 1394

Query: 2206 PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGP------PGLIGEQGISGPRGSGGAAGA 2259
            PG  G +G  G+ G +GE G  G  G  GP GP      PG  G +GI GP G  G  G+
Sbjct: 1395 PGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGS 1454

Query: 2260 PGERGRTGPLGRKGEPG---EPGPKGG------IGNRGPRGETGDDGRDGV-GSEGRRGK 2309
            PG  G  GP+G  G PG   + GPKG       IG  GP GE G+ G  G+ G +G  G 
Sbjct: 1455 PGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGP 1514

Query: 2310 KGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAG 2365
            KGE+G  G  GP G PG PGL G  GPKG +G  G +GP G  G  G PG PGP G
Sbjct: 1515 KGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPG 1570



 Score =  277 bits (709), Expect = 1e-73
 Identities = 161/354 (45%), Positives = 193/354 (54%), Gaps = 18/354 (5%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096
            +G++G RG  G  GP+G  G  G RG  G  G  G+ GP G +G  G  G PG+RG  G 
Sbjct: 894  NGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGP 953

Query: 2097 R---GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI 2153
            +   GFPG KG  G  G DGL G  G +G  G  G+ G PG  G  GP+G  GE G +G 
Sbjct: 954  QGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGE 1013

Query: 2154 RGDPGNPGQDSQE-----RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208
            RG PG PG   ++      G +G  GD GP G+PG+DG PG  G  G  G  G  G  G 
Sbjct: 1014 RGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGL 1073

Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2268
            KGN+G PG PG  G  G R   GPAG AGP G+ G  G  GP G  G  GAPGE+G  GP
Sbjct: 1074 KGNEGPPGPPGPAGSPGER---GPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGP 1130

Query: 2269 LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGE 2327
             GR G  G  G  G  G  GP GE GD G  G  G +G +G KGE+G PG  GP+G  G+
Sbjct: 1131 AGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQ 1190

Query: 2328 PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPA------GPKGNRGDSID 2375
            PG +G  G  G RG++G  G  G  G +G PG PGP       GP G +G++ D
Sbjct: 1191 PGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGD 1244



 Score =  275 bits (704), Expect = 4e-73
 Identities = 158/353 (44%), Positives = 188/353 (53%), Gaps = 20/353 (5%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDG---YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094
            G+ G  GP G +GP+G  GE G    RG+PG  G PGE+G PG+ G +G +G PG  G+ 
Sbjct: 988  GKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLP 1047

Query: 2095 GS------RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGP---RGEK 2145
            G       RGFPG++G  G +G  GL G +G  G PG +G  G  G  G  GP    G  
Sbjct: 1048 GKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRP 1107

Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP 2205
            G +G  G  G+ G PG+   + GP G  G  GP+G+PG  G  G PGE G  G  G  G 
Sbjct: 1108 GPQGPPGPAGEKGAPGEKGPQ-GPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQ 1166

Query: 2206 PGAKGNKGGPGQPGFEGEQGTRGAQGPA------GPAGPPGLIGEQGISGPRGSGGAAGA 2259
             G+KG+KG  G PG  G QG  G  GP+      GP G  GL G++G  GPRG  G  G 
Sbjct: 1167 KGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGP 1226

Query: 2260 PGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGY 2318
             G +G  GP G KGE G+ G  G  G  GPRG +G  G DG  G  G  G  G  G  G 
Sbjct: 1227 VGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGE 1286

Query: 2319 PGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
            PG  G PG PG  G  GPKG RG +G SGP G  G  G  G PG  GPKG+ G
Sbjct: 1287 PGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPG 1339



 Score =  272 bits (695), Expect = 4e-72
 Identities = 156/351 (44%), Positives = 187/351 (53%), Gaps = 30/351 (8%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGP------------GERGPPGVNGTQGF 2084
            +G  G+RGP G  GP G PG  G  G PG +G P            G+ GPPG  G  G 
Sbjct: 942  AGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGP 1001

Query: 2085 QGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSS---GEKGNPGRRGDKGP 2141
            QG  G+ G  G RG PG  G  GE GL GL G++G KG PG +   G+ G PG RG  G 
Sbjct: 1002 QGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGD 1061

Query: 2142 RGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFG 2201
            RG  G  G +G++G+ G PG      GP G  G+ GP G  G  G+PG PG  G  G  G
Sbjct: 1062 RGLPGPVGALGLKGNEGPPGPP----GPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAG 1117

Query: 2202 RRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPG 2261
             +G PG KG +G  G+   +G QG  G  GPAGP GPPG  G++G  G  G  G+ G  G
Sbjct: 1118 EKGAPGEKGPQGPAGR---DGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKG 1174

Query: 2262 ERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGP 2321
            E+G  GP G +G  G+PGP G  G  GPRG+         G  G++G +G RGFPG PGP
Sbjct: 1175 EQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQ--------GLFGQKGDEGPRGFPGPPGP 1226

Query: 2322 KGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
             G  G PG  G  G  G  G+ G  GPPG  G  G PG  GP GP G  G+
Sbjct: 1227 VGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGN 1277



 Score =  272 bits (695), Expect = 4e-72
 Identities = 159/378 (42%), Positives = 188/378 (49%), Gaps = 44/378 (11%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDG---YRGYPGD---------------EGGPGERGPPGVN 2079
            G  G  G  G  GP G+PG+DG    RG+PGD               EG PG  GP G  
Sbjct: 1030 GLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSP 1089

Query: 2080 GTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDK 2139
            G +G  G  G  G+ G  G  G  G  GE G  G  G  G  G  G  G  G PG  G  
Sbjct: 1090 GERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPV 1149

Query: 2140 GPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGG 2199
            GP GE G++G++G  G  G+ G D  E+GP G TG  GP+G PG  G  G PG  G+ G 
Sbjct: 1150 GPPGEDGDKGEIGEPGQKGSKG-DKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGL 1208

Query: 2200 FGRR---------GPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGP 2250
            FG++         GPPG  G +G PG PG +GE G  G  GP GP GP G  G  G  GP
Sbjct: 1209 FGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGP 1268

Query: 2251 RGSGGAAGAP---GERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG------- 2300
            +G  G  G P   GE+G  G  G  G PGE GP G  G RG +GE+G  G  G       
Sbjct: 1269 QGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGP 1328

Query: 2301 VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDP-- 2358
             G +G +G  G  GFPG PGP G PG  G +G  G KG  G  G +G PG  G+ G    
Sbjct: 1329 PGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGP 1388

Query: 2359 ----GYPGPAGPKGNRGD 2372
                G PGPAGP+G +G+
Sbjct: 1389 PGKRGPPGPAGPEGRQGE 1406



 Score =  271 bits (693), Expect = 8e-72
 Identities = 158/365 (43%), Positives = 187/365 (51%), Gaps = 42/365 (11%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G +GDRG IG  GP+G  G +G +G  G  G PG  GPPG  G  G  G PG        
Sbjct: 823  GIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPG-------- 874

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157
             +PG +G  G IG  G  G +G+KG  G+ G+ G  G+RG  GPRGE+G RG  G  G  
Sbjct: 875  -YPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPK 933

Query: 2158 GNPGQDSQ-----ERGPKGETGDLG------PMGVPGRDGVPGGPGETGKNGGFGRRGPP 2206
            GN G D       ERGP G  G  G      P G PG+DG+PG PG+ G+ G  G+ GPP
Sbjct: 934  GNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPP 993

Query: 2207 GAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGA------- 2259
            G  G  G  G  G  G  G RG  GP GP G  GL G  G  G +G  G AG        
Sbjct: 994  GPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPP 1053

Query: 2260 -----PGERGRTGPL------GRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRR 2307
                 PG+RG  GP+      G +G PG PGP G  G RGP G  G  G  G  G +G  
Sbjct: 1054 GLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPP 1113

Query: 2308 GKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPK 2367
            G  GE+G PG  GP+G  G  GL    GP G+ G  G  GPPG  G KG+ G PG  G K
Sbjct: 1114 GPAGEKGAPGEKGPQGPAGRDGLQ---GPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSK 1170

Query: 2368 GNRGD 2372
            G++G+
Sbjct: 1171 GDKGE 1175



 Score =  271 bits (692), Expect = 1e-71
 Identities = 157/339 (46%), Positives = 178/339 (52%), Gaps = 17/339 (5%)

Query: 2040 RGDRGPIGSIG---PKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096
            RG  GP+G  G   P G PG  G +G PGD G  G RG  G  G  G  G  G+ G  G+
Sbjct: 558  RGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGA 617

Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGD 2156
            RG PG+ G  G+ G DGL G  G+KG  G  G  G PG  GD G RG+ GE   VG RG 
Sbjct: 618  RGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGE---VGPRGL 674

Query: 2157 PGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPG 2216
            PG P       GP+G  G  GP G PG  GV G  G+ G  G  G +G PG  G +G PG
Sbjct: 675  PGEP-------GPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPG 727

Query: 2217 QPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPG 2276
              G  G QG  G  G  GP G PGL G  G  GP G  G  G PGE+G  GP G +G  G
Sbjct: 728  AQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIG 787

Query: 2277 EPGP---KGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGLNG 2332
             PGP   KG  G RG +G  G+ G DG  G +G  G KG+RG  G PGP+G  G  G  G
Sbjct: 788  YPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKG 847

Query: 2333 TTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
              GP G  G  G  G  G +G  G PGYPG  GPKG+ G
Sbjct: 848  RGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIG 886



 Score =  270 bits (689), Expect = 2e-71
 Identities = 166/388 (42%), Positives = 192/388 (49%), Gaps = 50/388 (12%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNG---TQGFQGCPG 2089
            P   +G+ G  GP GS G KG PG+ G +G  G +G PG  G PG  G   + G +G PG
Sbjct: 563  PMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPG 622

Query: 2090 QRGVKGSRGF------PGEKGEVGEIGLDGL------DGEDGDKGLPGSSGEKGNPGRRG 2137
            Q G KG RGF      PGEKG  G+ G  G       DGE GD G  G  G  G PG RG
Sbjct: 623  QTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRG 682

Query: 2138 DKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVP---GGPGET 2194
              GP+G  G  G  G+ G  G PG      GP+GE G  G  G PG  G+P   G  G  
Sbjct: 683  LLGPKGPPGPPGPPGVTGMDGQPGPKGNV-GPQGEPGPPGQQGNPGAQGLPGPQGAIGPP 741

Query: 2195 GKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSG 2254
            G+ G  G+ G PG  G  G PG PG EG  G +G QGP GP GP G  G +G+ G  G  
Sbjct: 742  GEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIR 801

Query: 2255 GAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGS----------- 2303
            G  G  GE+G  G  G KG+ G  G +G IG  GPRGE G +G  G G            
Sbjct: 802  GLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPP 861

Query: 2304 --------------EGRRGKKGERGFPGYPGP------KGNPGEPGLNGTTGPKGIRGRR 2343
                           GR+G KG  GFPG+PG       +G PG+PG  G  GP G RG R
Sbjct: 862  GEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGER 921

Query: 2344 GNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
            G  G  G  G KG+ G  GPAGP G RG
Sbjct: 922  GPRGITGKPGPKGNSGGDGPAGPPGERG 949



 Score =  268 bits (684), Expect = 8e-71
 Identities = 168/391 (42%), Positives = 195/391 (49%), Gaps = 60/391 (15%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G +G  GP G  GP G PGE G  G PG  G PG +GP    G+ GF G PG  G KG R
Sbjct: 844  GPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGP---KGSIGFPGFPGANGEKGGR 900

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGN---------PGRRGDKGPRGE---- 2144
            G PG+ G  G+ G  G  GE G +G+ G  G KGN         PG RG  GP+G     
Sbjct: 901  GTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFP 960

Query: 2145 --KGERGDVGIRGDPGNPGQDSQER--------------GPKGETGDLGPMGVPGRDGVP 2188
              KG  G  G  G PG+PGQ  +                GP+G TG+ GPMG  G  G P
Sbjct: 961  GPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPP 1020

Query: 2189 GGPGE------TGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQ---------GTRGAQGPA 2233
            G PGE       GK G  G  GP G  G  G PG  GF G++         G +G +GP 
Sbjct: 1021 GPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPP 1080

Query: 2234 GPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGET 2293
            GP GP G  GE+G +G  G  G  G PG +G  GP G KG PGE GP+G  G  G +G  
Sbjct: 1081 GPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPV 1140

Query: 2294 GDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNS------ 2346
            G  G  G VG  G  G KGE G PG  G KG+ GE G  G TGP+G  G+ G S      
Sbjct: 1141 GLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEP 1200

Query: 2347 ---GPPGIVGQKGDP---GYPGPAGPKGNRG 2371
               G  G+ GQKGD    G+PGP GP G +G
Sbjct: 1201 GPRGQQGLFGQKGDEGPRGFPGPPGPVGLQG 1231



 Score =  229 bits (584), Expect = 3e-59
 Identities = 133/304 (43%), Positives = 160/304 (52%), Gaps = 25/304 (8%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G  G++G  G  G  G+PGE G  G  G+ G  GE GP G  G  G +G PG  G KGS 
Sbjct: 1279 GAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSP 1338

Query: 2098 G---FPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154
            G   FPG+ G  GE G  G DG  GDKG  G  G+ G+PG  G+ GP G  G+RG  G  
Sbjct: 1339 GPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPA 1398

Query: 2155 GDPGNPGQDSQE-----RGPKGETGDLGPMGVPGR---DGVPGGPGETGKNGGFGRRGPP 2206
            G  G  G+   +      GP G+TG +GP G PG+   DG+ G PG  G+ G  G  GP 
Sbjct: 1399 GPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPD 1458

Query: 2207 GAKGNKGGPGQPGFEGEQGTRGAQGPAGPAG---PPGLIGEQGISGPRGSGGAAGAPGER 2263
            G  G  G PG PG +G+ G +G +G  G  G   PPG  GE+G  G  G  G++G  GE+
Sbjct: 1459 GPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQ 1518

Query: 2264 GRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKG 2323
            G TGP G  G PG PG  G  G +G +           GS G  G KGE G PG PGP G
Sbjct: 1519 GITGPSGPIGPPGPPGLPGPPGPKGAK-----------GSSGPTGPKGEAGHPGPPGPPG 1567

Query: 2324 NPGE 2327
             PGE
Sbjct: 1568 PPGE 1571



 Score =  194 bits (492), Expect = 2e-48
 Identities = 137/343 (39%), Positives = 158/343 (46%), Gaps = 39/343 (11%)

Query: 2057 EDGYRGYPGDEGGPGERGPPGVNGTQG--FQGCPGQRGVKGSRGFPG--EKGEVGEIGLD 2112
            E+ Y  Y      P E GP G+   Q   ++G  G RG KG +G P   E G +    ++
Sbjct: 414  ENYYDPYYDPTSSPSEIGP-GMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGML----IE 468

Query: 2113 GLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQ---ERGP 2169
            G  G +G  GLPG  G  G  G+ GD G RG  G  G  G  G PG PG         G 
Sbjct: 469  GPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGG 528

Query: 2170 KGETGDLGPMGVPGRDGVPGG---------PGETGKNGGFGRRGPPGAKGNKGGPGQPGF 2220
             G+ G  GPM V  ++               G  G  G  GR GP G  G+ G  G+PG 
Sbjct: 529  GGDAGSKGPM-VSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGD 587

Query: 2221 EGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGE--- 2277
             G QG RG QGP GPAG PG  G  G  G RG  G  G  G+RG  G  G  GE G    
Sbjct: 588  VGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGD 647

Query: 2278 ------PGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLN 2331
                  PGP G  G RG  GE G  G    G  G RG  G +G PG PGP   PG  G++
Sbjct: 648  PGPSGPPGPPGDDGERGDDGEVGPRGLP--GEPGPRGLLGPKGPPGPPGP---PGVTGMD 702

Query: 2332 GTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGP---AGPKGNRG 2371
            G  GPKG  G +G  GPPG  G  G  G PGP    GP G +G
Sbjct: 703  GQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKG 745



 Score =  165 bits (417), Expect = 8e-40
 Identities = 133/387 (34%), Positives = 158/387 (40%), Gaps = 78/387 (20%)

Query: 2054 IPGEDGYRGYPGDE--GGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGL 2111
            +P ED Y   P D+   G GE  P            P       +   P      G   L
Sbjct: 341  VPSEDYYTPSPYDDLTYGEGEENPDQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDL 400

Query: 2112 DGLDGEDGDKGL----------PGSSGEKGNPGR--------RGDKGPRGEKGERGDVGI 2153
            +G   E+  + L          P SS  +  PG          G  GPRGEKG++G+  I
Sbjct: 401  EGEFTEETIRNLDENYYDPYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAI 460

Query: 2154 RGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKG 2213
                  PG   +  GP G  G  G  G PG  G  G  G+ G+ G  GR G PGA G  G
Sbjct: 461  I----EPGMLIE--GPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPG 514

Query: 2214 GPGQ----PGFEGEQGTRGAQGPA--------------------GPAGPPGLIGEQGISG 2249
             PG     P   G  G  G++GP                     GPAGP GL G  G  G
Sbjct: 515  PPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVG 574

Query: 2250 PRGSGGAAGAPGERGRTGPLG------------RKGEPGEPGPKGGIGNRGPRGETGDDG 2297
            P GSGG  G PG+ G  GP G            R+G  G  G +G  G  GP+G+ G DG
Sbjct: 575  PPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDG 634

Query: 2298 RDGV-GSEGRRGKKGERGFPGYPGP------------KGNPGEPGLNGTTGPKGIRGRRG 2344
              G+ G +G RG  G  G PG PG             +G PGEPG  G  GPK   G  G
Sbjct: 635  LAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPK---GPPG 691

Query: 2345 NSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
              GPPG+ G  G PG  G  GP+G  G
Sbjct: 692  PPGPPGVTGMDGQPGPKGNVGPQGEPG 718



 Score = 52.8 bits (125), Expect = 5e-06
 Identities = 27/63 (42%), Positives = 31/63 (49%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRG 2092
            P   SG +G++G  G  GP G PG  G  G PG +G  G  GP G  G  G  G PG  G
Sbjct: 1508 PQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPG 1567

Query: 2093 VKG 2095
              G
Sbjct: 1568 PPG 1570


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score =  296 bits (758), Expect = 2e-79
 Identities = 164/342 (47%), Positives = 189/342 (55%), Gaps = 10/342 (2%)

Query: 2038 GQRGDRGPIGSIGPKG---IPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094
            G RG  GP+G +G KG    PG  G  G+PGD G PG+ GP G+ G  G +G PG RG  
Sbjct: 883  GARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQL 942

Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154
            G  G  G  G  G  GL+G  G  G  G PG  G KG PG  G  GP GE+G  G +G+ 
Sbjct: 943  GPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLV 1002

Query: 2155 GDPGNPGQ--DSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPG---AK 2209
            G+PG  G+  D    GP G  G  G MG PG  G  G PGE G  G  G RGPPG   AK
Sbjct: 1003 GEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAK 1062

Query: 2210 GNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPL 2269
            G +G  G  G  GEQG+RG +GP GP G PG  G+QG++G RG  G+ G PG  G +GP 
Sbjct: 1063 GRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPP 1122

Query: 2270 GRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPG 2329
            G KG PGEPGP+G  G  GP GE G  G    G+ G  G  GE G  G  GP G PGE G
Sbjct: 1123 GTKGLPGEPGPQGPQGPIGPPGEMGPKGPP--GAVGEPGLPGEAGMKGDLGPLGTPGEQG 1180

Query: 2330 LNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
            L G  G  G+ G  G  GP G+ G +GDPG  G  G KG  G
Sbjct: 1181 LIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEG 1222



 Score =  277 bits (709), Expect = 1e-73
 Identities = 165/397 (41%), Positives = 201/397 (50%), Gaps = 58/397 (14%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNG------TQGFQGCPGQR 2091
            G +G RGP G  GP G  G  G +G PG +G PG  G  GV G      ++GF G PG  
Sbjct: 1060 GAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPS 1119

Query: 2092 GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGR---RGDKGPRGEKGER 2148
            G  G++G PGE G  G  G  G  GE G KG PG+ GE G PG    +GD GP G  GE+
Sbjct: 1120 GPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQ 1179

Query: 2149 GDVGIRGDPGNPGQ-----------DSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKN 2197
            G +G RG+PG  G            D  + GP GE G+ G  G+ G DG PG PG TG  
Sbjct: 1180 GLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVR 1239

Query: 2198 GGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAA 2257
            G  G+ G  G KG  G  G  G++G+ G  G  G  GP G PG  G +G  GP G+ G  
Sbjct: 1240 GPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRM 1299

Query: 2258 GAPGERGRTG---------------PLGRKGE----------PGEPGPKGGIGNRGPRGE 2292
            GA GE G  G               P G KGE          PG PG +G +G+RG RGE
Sbjct: 1300 GAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGE 1359

Query: 2293 TGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKG------------I 2339
             GD G  G  G +G RGK G++G PG+PGP+G PG  G  G  GPKG            +
Sbjct: 1360 PGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGV 1419

Query: 2340 RGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQ 2376
            +G +G  GP G+VG++G  G  GP G  G  G +  Q
Sbjct: 1420 QGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQ 1456



 Score =  277 bits (708), Expect = 1e-73
 Identities = 162/367 (44%), Positives = 200/367 (54%), Gaps = 33/367 (8%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G +GD G  G  G  G PG  G++GYPG  G PGE+G PG  G+ G +G PG++G+ G  
Sbjct: 688  GAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPV 747

Query: 2098 GFPGEKGEVGEIGLD---GLDGEDGDKGLPGSSGEKGN------PGRRGDKGPRGEKGER 2148
            G PG KG  G IGL    GL G DG++GLPG  G++G       PG  G++GP G  G  
Sbjct: 748  GDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNP 807

Query: 2149 GDVGIRGDPGNPGQDSQ--------ERGPKGETGDLGPMGVP------GRDGVPGGPGET 2194
            G++G+ G PG PG              GPKG  G +G +G P      G  GVPG  G+ 
Sbjct: 808  GELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDP 867

Query: 2195 GKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGP---R 2251
            G  G  G +G PG  G +G PG  G  G++G+ G  GP GP G PG IG  G +GP   +
Sbjct: 868  GFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMK 927

Query: 2252 GSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV----GSEGRR 2307
            G  GA G PG RG+ GP G +G  G PG  G  G  G +G  G  G DGV    G  GR 
Sbjct: 928  GKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRP 987

Query: 2308 GKKGERGFPGYPGPKGNP---GEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPA 2364
            G  GE+GF G+ G  G P   GE G  G  GP G+ G +G+ G PG+ G  G PG PGP 
Sbjct: 988  GPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQ 1047

Query: 2365 GPKGNRG 2371
            GP G+RG
Sbjct: 1048 GPPGSRG 1054



 Score =  276 bits (707), Expect = 2e-73
 Identities = 159/363 (43%), Positives = 190/363 (52%), Gaps = 29/363 (7%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRG 2092
            P    G  G+ GP G  GP G PGE G +G PG  G PG  G  G+ G  G  G PG++G
Sbjct: 1121 PPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQG 1180

Query: 2093 VKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVG 2152
            + G RG PG +G+ G +G DGL G+ GD G  G  GEKG  G  G+ GP G  G  G  G
Sbjct: 1181 LIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRG 1240

Query: 2153 IRGDPGNPGQDSQ--ERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKG 2210
              G  G  G+  +   +G KG  G LG MGVPG  G PG PG  G  G     GP GA G
Sbjct: 1241 PEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSL---GPTGAPG 1297

Query: 2211 NKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLG 2270
              G  G+PG  G  G +G  GP GP GP G  GEQG  G   + G  G PG+RG  G  G
Sbjct: 1298 RMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGK--AEGPPGPPGDRGPVGDRG 1355

Query: 2271 RKGEPGEPGPKGGIGNRGPRGETGDDGRDG-------------VGSEGRRGKKGERGFP- 2316
             +GEPG+PG  G  G +G RG+ G  G+ G              G+EG +GK+G+ G P 
Sbjct: 1356 DRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPG 1415

Query: 2317 --------GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKG 2368
                    G PGP+G  G  GL G  GP G+ GR G +G  G  G  GDPG  GPAG +G
Sbjct: 1416 RRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRG 1475

Query: 2369 NRG 2371
            N G
Sbjct: 1476 NPG 1478



 Score =  274 bits (701), Expect = 9e-73
 Identities = 162/399 (40%), Positives = 205/399 (51%), Gaps = 69/399 (17%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRG---VK 2094
            G+ G +GP G++G  G+PGE G +G  G  G PGE+G  G  G  G +G  G  G   +K
Sbjct: 1144 GEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLK 1203

Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPG---------SSGEKGNPGRRGDKGPRGEK 2145
            G RG PG  GE GE G +GL GEDG  G PG          SG++G  GR G KG +G +
Sbjct: 1204 GDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQ 1263

Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPG------------- 2192
            G+ G++G+ GDPG PG      GPKG  G LGP G PGR G  G PG             
Sbjct: 1264 GQLGEMGVPGDPGPPGTP----GPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGP 1319

Query: 2193 --------ETGKNGGFGR----------RGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAG 2234
                    E G+ G  G+          RGP G +G++G PG PG+ G++G +G +G  G
Sbjct: 1320 LGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPG 1379

Query: 2235 PAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGE---PGPKGGIGNRG--- 2288
              G PG  G +G  GP+GS GA G  G++G+ G  GR+G  G    PGP+G +G +G   
Sbjct: 1380 QQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEG 1439

Query: 2289 ---------------PRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNG 2332
                            +GE GDDG  G +G  G+RG  G  G PG  GP G  GE GL G
Sbjct: 1440 IAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPG 1499

Query: 2333 TTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
              GP G RG  G +G PG  G+ G  G PG +G  G  G
Sbjct: 1500 QLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPG 1538



 Score =  272 bits (695), Expect = 4e-72
 Identities = 151/343 (44%), Positives = 184/343 (53%), Gaps = 23/343 (6%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G++GDRG    +GP G+PG  G  G+PG  GG G  G PG  G  G +G PG RG KG R
Sbjct: 1009 GEKGDRG---MMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRR 1065

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKG---ERGDVGIR 2154
            G  G  G  GE G  GL G  G +G PG  G++G  G RG  G RG  G     G  G +
Sbjct: 1066 GPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTK 1125

Query: 2155 GDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGG 2214
            G PG PG    + GP G  G++GP G PG  G PG PGE G  G  G  G PG +G  G 
Sbjct: 1126 GLPGEPGPQGPQ-GPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQ 1184

Query: 2215 PGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGE 2274
             G+PG EG+         +GP GP GL G++G  GP G        GE+G+ G +G  G 
Sbjct: 1185 RGEPGLEGD---------SGPMGPDGLKGDRGDPGPDGE------HGEKGQEGLMGEDGP 1229

Query: 2275 PGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGT 2333
            PG PG  G  G  G  G+ G+ GR G  G++G +G+ GE G PG PGP G PG  G  G+
Sbjct: 1230 PGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGS 1289

Query: 2334 TGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQ 2376
             GP G  GR G  G PG+ G  G  G  GP GP G +G+  +Q
Sbjct: 1290 LGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQ 1332



 Score =  268 bits (685), Expect = 6e-71
 Identities = 165/401 (41%), Positives = 199/401 (49%), Gaps = 50/401 (12%)

Query: 2021 LDNIAEKACCGVPCKCS--GQRGDRGPIGSIGPKGIPGEDGYRGYPGD------EGGPGE 2072
            L  + +K   G P      G  GD GP G  GP+G+ G+ G RG PG       EG  G 
Sbjct: 891  LGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGP 950

Query: 2073 RGPPGVNGTQG------FQGCPGQRGVKGSRGFPGEKGEVGE---------IGLDGLDGE 2117
             GPPG  G +G      F G PG  GVKG  G PG  G VGE         +G  G+ GE
Sbjct: 951  MGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGE 1010

Query: 2118 DGDKGL------PGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE----- 2166
             GD+G+      PG  G  G+PG  G  G  GE G +G  G RG PG  G   +      
Sbjct: 1011 KGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGP 1070

Query: 2167 RGPKGETGDLGPMGVPGRDGVPGGPGE---TGKNGGFGRR------GPPGAKGNKGGPGQ 2217
             GP GE G  G  G PG  G PG PG+    G+ G  G R      GP G  G KG PG+
Sbjct: 1071 DGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGE 1130

Query: 2218 PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGE 2277
            PG +G QG  G  G  GP GPPG +GE G+ G  G  G  G  G  G  G +G++GEPG 
Sbjct: 1131 PGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGL 1190

Query: 2278 PGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYP------GPKGNPGEPGL 2330
             G  G +G  G +G+ GD G DG  G +G+ G  GE G PG P      GP+G  G+ G 
Sbjct: 1191 EGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGE 1250

Query: 2331 NGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
             G TG KG +G +G  G  G+ G  G PG PGP G +G+ G
Sbjct: 1251 KGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLG 1291



 Score =  258 bits (658), Expect = 9e-68
 Identities = 153/366 (41%), Positives = 189/366 (51%), Gaps = 31/366 (8%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096
            SG++G++G  G+ G KG  G+ G  G PGD G PG  GP G  G+ G  G PG+ G +G 
Sbjct: 1245 SGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGE 1304

Query: 2097 ---RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSS-GEKGNPGRRGDKGPRGEKGERGDVG 2152
                G+ G KG VG +G  G  GE G++G  G + G  G PG RG  G RG++GE GD G
Sbjct: 1305 PGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPG 1364

Query: 2153 ---------IRGDPGNPGQDSQER-----GPKGETGDLGPMGVPGRDGVPG--------- 2189
                     +RG PG  GQ          GPKG  G  GP G  G+ G PG         
Sbjct: 1365 YPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQG 1424

Query: 2190 --GP-GETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQG 2246
              GP G  G+ G  G  GP G  G  G  GQ G +G+ G  G  GPAG  G PG+ G  G
Sbjct: 1425 LPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPG 1484

Query: 2247 ISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEG 2305
              GP G  G +G PG+ G  G  G +G  G PG +G  G++G  G++G+ G  G+ G  G
Sbjct: 1485 AQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFG 1544

Query: 2306 RRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAG 2365
             +G  G+ GF G  GP+G PG  G  G  GP GI G  G  GP G  G +GD G  GP G
Sbjct: 1545 PKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRG 1604

Query: 2366 PKGNRG 2371
            P G RG
Sbjct: 1605 PPGPRG 1610



 Score =  255 bits (651), Expect = 6e-67
 Identities = 154/371 (41%), Positives = 191/371 (51%), Gaps = 49/371 (13%)

Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEG---GPGERGPPGVNGTQGFQGC 2087
            G+P    G RG RGP G  G  G+PG  G +G  GD G   G    G  G  G  G  G 
Sbjct: 646  GIP----GARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGN 701

Query: 2088 PGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGE 2147
            PG  G KG +G+PG  G  GE G  G +G  G KG P   G +G PG  GD GP+G +G 
Sbjct: 702  PGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYP---GRQGLPGPVGDPGPKGSRGY 758

Query: 2148 RGDVGI---------RGDPGNPGQDSQ-----------ERGPKGETGDLGPMGVPGRDGV 2187
             G  G+         RG PG PG+  +           ERGP G  G+ G +G+PG  GV
Sbjct: 759  IGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGV 818

Query: 2188 PGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGI 2247
            PG  G+ G  G  G  GP G KG  G  G+PG +G++G +G          PG+ G+ G 
Sbjct: 819  PGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGV---------PGVSGDPGF 869

Query: 2248 SGPRGSGGAAGAPGERGRTGPLGRKGE------PGEPGPKGGIGNRGPRGETGDDGRDG- 2300
             G +GS G  G PG RG+ GPLG+ G+      PG PGP+G  G+ GP G+ G +G  G 
Sbjct: 870  QGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGK 929

Query: 2301 VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGY 2360
             G+ G  G +G+ G  G  GP G PG PGL G  G KG  GR    G  G+ G+ GDPG 
Sbjct: 930  PGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGR---PGLDGVKGEPGDPGR 986

Query: 2361 PGPAGPKGNRG 2371
            PGP G +G  G
Sbjct: 987  PGPVGEQGFMG 997



 Score =  237 bits (605), Expect = 1e-61
 Identities = 142/340 (41%), Positives = 173/340 (50%), Gaps = 19/340 (5%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQG-------CPGQ 2090
            G RG  GP G+ G  G  GE G  GY G +G  G  GPPG  G +G QG        PG 
Sbjct: 1285 GSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGP 1344

Query: 2091 RGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD 2150
             G +G  G  G++GE G+ G  G +G  G +G PG  G+ G+PG RG  GP+G KG  G 
Sbjct: 1345 PGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGP 1404

Query: 2151 VGIRGDPGNPGQDSQER-----GPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP 2205
             G +G  G PG+   +      GP+G  G  G  G+ G DG+PG  G+ G+ G  G  G 
Sbjct: 1405 KGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGD 1464

Query: 2206 PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGR 2265
            PG  G  G  G PG  G     GAQGP G  G  GL G+ G  G RG+ G  G PG +G 
Sbjct: 1465 PGPMGPAGKRGNPGVAG---LPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGE 1521

Query: 2266 TGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV----GSEGRRGKKGERGFPGYPGP 2321
             G  G+ G+ GE G  G  G  GP+G  GD G  G+    G  G  GK+G  G  G  GP
Sbjct: 1522 PGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGP 1581

Query: 2322 KGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYP 2361
             G PG  G  G+ G  G++G RG  GP G  G  G PG P
Sbjct: 1582 SGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGP 1621



 Score =  176 bits (446), Expect = 3e-43
 Identities = 115/275 (41%), Positives = 138/275 (50%), Gaps = 38/275 (13%)

Query: 2127 SGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDG 2186
            +G    P   G  GP+G+ G  G  G+ G PG PG     RGP+G     GP G PG  G
Sbjct: 615  AGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPG----ARGPRGPP---GPYGNPGLPG 667

Query: 2187 VPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQG 2246
             PG  G+ G  G    +   GAKG+ G PG  G  G  G +G +G  GPAG P   GEQG
Sbjct: 668  PPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHP---GEQG 724

Query: 2247 ISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEG 2305
              GP GS GA G PG +G  GP+   G+PG  G +G IG  G  G  G DG  G+ G  G
Sbjct: 725  QPGPEGSPGAKGYPGRQGLPGPV---GDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPG 781

Query: 2306 RRGKKGERGFPGY------PGPKGNPGEPGLNGT------------------TGPKGIRG 2341
            +RGK G  GFPG       PG  GNPGE GL G                    GPKG++G
Sbjct: 782  KRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKG 841

Query: 2342 RRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQ 2376
              G+ G PG+ G KG+ G PG +G  G +GD   Q
Sbjct: 842  LMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQ 876



 Score =  152 bits (385), Expect = 4e-36
 Identities = 96/237 (40%), Positives = 120/237 (50%), Gaps = 35/237 (14%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEG--------GP-GERGPPGVNGTQGFQGCP 2088
            G  G +G  G  GP G+PG DG  G  G++G        GP G+RG PGV G  G QG P
Sbjct: 1430 GVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPP 1489

Query: 2089 G---QRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEK 2145
            G   + G+ G  G PG++G  G  GL G  GE G KG PG SGE G PG  G  GP+G  
Sbjct: 1490 GFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPP 1549

Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGF---GR 2202
            G+ G  GI+G  G PG         G+ G +GP+G+ G  G+PG  G+ G  G +   G 
Sbjct: 1550 GDIGFKGIQGPRGPPGL-------MGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGP 1602

Query: 2203 RGPPGAKGNKGGPGQPG-------------FEGEQGTRGAQGPAGPAGPPGLIGEQG 2246
            RGPPG +G  G PG PG             F+    T GA  P   + P  L+ +QG
Sbjct: 1603 RGPPGPRGRPGPPGPPGGPIQLQQDDLGAAFQTWMDTSGALRPESYSYPDRLVLDQG 1659



 Score = 48.5 bits (114), Expect = 1e-04
 Identities = 40/151 (26%), Positives = 62/151 (41%), Gaps = 13/151 (8%)

Query: 2844 PTKNLVKFGHKQVNVPNNVTSSPTSNPVTTTKPVTTTKPVTTTT---KPVTTTTKPVTII 2900
            PT+        +  +P      PTS PV         KP+       +P   +T+P+   
Sbjct: 387  PTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPAEKPIQRNPGMPRPPPPSTRPLPPT 446

Query: 2901 NQPSVKPA---AAKPAPAKPVAAKPVATKMATVRPP--VAVKPATAAKPVAAK----PAA 2951
               S KP    A   A     A+KP + + +T +PP   A+  + A  P + +    PA 
Sbjct: 447  TSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSPAPTPGSTRSTRPPAT 506

Query: 2952 VRPPAAAAAKPVATKPEVPRPQAAKPAATKP 2982
            + PP +  + P  T P VP P +A   + KP
Sbjct: 507  MVPPTSGTSTP-RTAPAVPTPGSAPTGSKKP 536



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 42/156 (26%), Positives = 64/156 (41%), Gaps = 28/156 (17%)

Query: 2869 NPVTTTKPVTTTKPVTTTT----KPVTTTTKPVTIINQPSVKPAAA-----KPAPAKPVA 2919
            NP     P  +T+P+  TT    KP+ T  +    I   + KPA+A     KP P   ++
Sbjct: 429  NPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALS 488

Query: 2920 AKPVATKMAT--VRPPVAVKPATAAKPVAAKPAAVRPPAAA---AAKPVAT--------- 2965
            + P  T  +T   RPP  + P T+         AV  P +A   + KP+ +         
Sbjct: 489  SSPAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEASKKAGPK 548

Query: 2966 ----KPEVPRP-QAAKPAATKPATTKPMVKMSREVQ 2996
                KP   RP +AA+       TT+P  +  +  Q
Sbjct: 549  SSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQ 584



 Score = 39.3 bits (90), Expect = 0.063
 Identities = 35/132 (26%), Positives = 53/132 (40%), Gaps = 19/132 (14%)

Query: 2863 TSSPTSNPVTTTKPVTTTKPVTTTTKPVTTTTKPVTIINQPSVK--PAAAKPAPAKP--V 2918
            T  P S P   + P T+  P+ +      T     T    P+ K  P  ++P PA+    
Sbjct: 362  TKIPKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRP 421

Query: 2919 AAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPPAAAAAKPVATKPEVP---RPQAA 2975
            A KP+       RPP    P+T   P         P  +++ KP+ T           A+
Sbjct: 422  AEKPIQRNPGMPRPP---PPSTRPLP---------PTTSSSKKPIPTLARTEAKITSHAS 469

Query: 2976 KPAATKPATTKP 2987
            KPA+ + +T KP
Sbjct: 470  KPASARTSTHKP 481



 Score = 38.1 bits (87), Expect = 0.14
 Identities = 33/123 (26%), Positives = 49/123 (39%), Gaps = 17/123 (13%)

Query: 2867 TSNPVTTTKPVTTTKPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPVA--AKPVA 2924
            +S+P  T     +T+P  T   P + T+ P T    P+  P +A     KP+   A   A
Sbjct: 488  SSSPAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPT--PGSAPTGSKKPIGSEASKKA 545

Query: 2925 TKMATVRPPVAVKPATAAKPVAAKPAAVRP------------PAAAAAKPVATKPEVPRP 2972
               ++ R PV ++P  AA+ V       RP            PA   A P       PRP
Sbjct: 546  GPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLA-PAQFLSSSPRP 604

Query: 2973 QAA 2975
             ++
Sbjct: 605  TSS 607



 Score = 35.8 bits (81), Expect = 0.69
 Identities = 34/151 (22%), Positives = 54/151 (35%), Gaps = 11/151 (7%)

Query: 2870 PVTTTKPVTTTKPVTTTTKPVTTTTK-PVTIINQPSVKPAAAKPAPAKPVAAKPVATKMA 2928
            P +      T +P         T TK P ++  +PS    +  P  +     K   +   
Sbjct: 338  PASVGGSTRTPRPAAAQPSQKITATKIPKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFT 397

Query: 2929 TVRPPVAVKPATAAKPVAAKPAAVRPPAAAAAKPVATKPEVPRPQAAKPAATKPATT--- 2985
                P   +    ++PV   PA V  P   A KP+   P +PRP         P T+   
Sbjct: 398  KSALPTQKQVPPTSRPV---PARVSRP---AEKPIQRNPGMPRPPPPSTRPLPPTTSSSK 451

Query: 2986 KPMVKMSR-EVQVFEITENSAKLHWERAEPP 3015
            KP+  ++R E ++       A       +PP
Sbjct: 452  KPIPTLARTEAKITSHASKPASARTSTHKPP 482



 Score = 35.4 bits (80), Expect = 0.91
 Identities = 30/120 (25%), Positives = 46/120 (38%), Gaps = 23/120 (19%)

Query: 2865 SPTSNPVTTTKPVTTTKPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPVAAKPVA 2924
            +PT     +T+P  T  P T+ T             + P   PA   P  A   + KP+ 
Sbjct: 492  APTPGSTRSTRPPATMVPPTSGT-------------STPRTAPAVPTPGSAPTGSKKPIG 538

Query: 2925 TKMATVRPPVAVKPATAAKPVAAKPAAVRPPAAAAAKPVATKPEVPRPQAAKPA-ATKPA 2983
            ++ +    P         K    KP  +RP  AA   P++     P P+  +P+  T PA
Sbjct: 539  SEASKKAGP---------KSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPA 589


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score =  293 bits (749), Expect = 2e-78
 Identities = 164/373 (43%), Positives = 194/373 (52%), Gaps = 43/373 (11%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096
            +G  G  GP G  G +G PG  G++G PG  G PGE G PG  G  G  G PG  G +G 
Sbjct: 641  AGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGE 700

Query: 2097 RGFPGEKGEVGEIGLDG------LDGEDGDKGLPGSSGE---------KGNPGRRGDKGP 2141
            RGFPGE+G  G  GL G        G DG KG  G +G          +G PG RG  G 
Sbjct: 701  RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 760

Query: 2142 RGEKGERGDVGIRGDPGNPGQDSQE--------------RGPKGETGDLGPMGVPGRDGV 2187
             G KG+RGDVG +G  G PG+D                  G KGE G  GP G  G  G 
Sbjct: 761  AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA 820

Query: 2188 PGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGI 2247
            PG  GETG  G  G  GPPGA G  G  G+ G  G++G  GA GP GP+G PG  G  G+
Sbjct: 821  PGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGV 880

Query: 2248 SGPRGSGGAAGAPGERG------RTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV 2301
            +GP+G+ GA G PG  G      R GP G  G PG PGP G  G  GP+G  GD      
Sbjct: 881  TGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDS----- 935

Query: 2302 GSEGRRGKKGERGFPGYPGPKGNPGE---PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDP 2358
            G  GR G+ G +G  G PG KG PG+    G  G  GP+G+ G+RG  G PG  G++G P
Sbjct: 936  GPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFP 995

Query: 2359 GYPGPAGPKGNRG 2371
            G PGP+G  G +G
Sbjct: 996  GLPGPSGEPGKQG 1008



 Score =  290 bits (742), Expect = 2e-77
 Identities = 166/361 (45%), Positives = 189/361 (52%), Gaps = 38/361 (10%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G+ G  GP+G  GP G PG+ G  G  G  G  GERGPPG  G +GF G PG  GVKG R
Sbjct: 231  GEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHR 290

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157
            G+PG  G  GE G  G+ GE G      S GE G+PG  G +G  GE+G  G  G  G  
Sbjct: 291  GYPGLDGAKGEAGAPGVKGESG------SPGENGSPGPMGPRGLPGERGRTGPAGAAGAR 344

Query: 2158 GNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQ 2217
            GN GQ     GP G  G +GP G PG  G PG  GE G  G    RGP GA+G +G PG 
Sbjct: 345  GNDGQP----GPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGA---RGPEGAQGPRGEPGT 397

Query: 2218 PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGE 2277
            PG  G  G  G  G  G  G  G  G  GI+G  G  G  G PG +G TGPLG KG+ GE
Sbjct: 398  PGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGE 457

Query: 2278 PGPKGGIGNRGPRGETGDDGRDG----VGSEGRRGKKGE------------------RGF 2315
            PG  G  G +GP+GE G  G  G     G EG+RG +GE                  RGF
Sbjct: 458  PGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGF 517

Query: 2316 P---GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
            P   G  GPKG PGE G +G  GPKG  G  G  G PG+ G +G  G PG AGP+G  G 
Sbjct: 518  PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGP 577

Query: 2373 S 2373
            S
Sbjct: 578  S 578



 Score =  283 bits (723), Expect = 2e-75
 Identities = 173/406 (42%), Positives = 202/406 (49%), Gaps = 74/406 (18%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGG------------------PGERGPPGV 2078
            +G+ GD GP G +GP G PGEDG  G PG +G                   PG+ G  G+
Sbjct: 563  TGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGL 622

Query: 2079 NGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGD 2138
             G  G +G PG+ G  G+ G PG  G  GE G  G  G  G +GLPG  G  G  G+ GD
Sbjct: 623  PGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGD 682

Query: 2139 K------------GPRGEK---GERGDVGI------RGDPGNPGQDSQERGPKGETGDLG 2177
            +            GPRGE+   GERG  G       RG PG PG D    GPKG +G  G
Sbjct: 683  QGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTD----GPKGASGPAG 738

Query: 2178 PMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAG 2237
            P G  G  G+ G PGE G  G  G +G  G  G KG  G PG +G +G  G  GP GPAG
Sbjct: 739  PPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAG 798

Query: 2238 PPGLIGEQGISGPRGSGGAAGAPGERGRTGP---------------LGRKGEPGEPGPKG 2282
              G  GE G  GP GS GA GAPGERG TGP                G KGE GE G KG
Sbjct: 799  ANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKG 858

Query: 2283 GIGNRGPRGETGDDGRDG-------VGSEGRRGKKGERGFPGY------PGPKGNPGEPG 2329
              G  GP+G +G  G  G        G+ G +G  G  GFPG       PG  GNPG PG
Sbjct: 859  DAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG 918

Query: 2330 LNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSID 2375
              G +G  G +G RG+SGPP   G+ G+PG  GPAGP G +G+  D
Sbjct: 919  PPGPSGKDGPKGARGDSGPP---GRAGEPGLQGPAGPPGEKGEPGD 961



 Score =  279 bits (713), Expect = 4e-74
 Identities = 158/349 (45%), Positives = 180/349 (51%), Gaps = 12/349 (3%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096
            +G  G RG  G  GP G PG  G  G PG  G PG +G  G  G +G +G  G RG  G+
Sbjct: 338  AGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGT 397

Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGD 2156
             G PG  G  G  G DG+ G  G  G PG +G  G PG RG  GP+G  G  G  G  G+
Sbjct: 398  PGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGE 457

Query: 2157 PGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPG---AKGNKG 2213
            PG  G    E+GPKGE G  GP G PG  G  G  G  G+ GG G  GPPG   A GN+G
Sbjct: 458  PGIAGFKG-EQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRG 516

Query: 2214 GPGQPGFEGEQGTRGAQGPAGPAGP------PGLIGEQGISGPRGSGGAAGAPGERGRTG 2267
             PGQ G  G +G  G +GP+G AGP      PG  GE G+ G RG  G  G  G +G+ G
Sbjct: 517  FPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVG 576

Query: 2268 PLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGE 2327
            P G  GE G PGP G  G RG  G  G  G  G  + G  GK GE+G PG PG +G PG+
Sbjct: 577  PSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKG--ANGEPGKAGEKGLPGAPGLRGLPGK 634

Query: 2328 PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQ 2376
             G  G  GP G  G  G  G  G  G  G  G PGP GP G  G   DQ
Sbjct: 635  DGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQ 683



 Score =  276 bits (706), Expect = 2e-73
 Identities = 171/406 (42%), Positives = 200/406 (49%), Gaps = 63/406 (15%)

Query: 2031 GVPCKCSGQRGDRGPIGSIG---PKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGC 2087
            G P K +G+RG  GP G+ G     G+PG  G+RGYPG +G  GE G PGV G  G  G 
Sbjct: 258  GKPGK-AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGE 316

Query: 2088 PGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGE---------KGNPGRRGD 2138
             G  G  G RG PGE+G  G  G  G  G DG  G  G  G           G PG +G+
Sbjct: 317  NGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGE 376

Query: 2139 KGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNG 2198
             GP G +G  G  G RG+PG PG      GP G +G+ G  G+PG  G  G PG  G  G
Sbjct: 377  AGPTGARGPEGAQGPRGEPGTPGSP----GPAGASGNPGTDGIPGAKGSAGAPGIAGAPG 432

Query: 2199 GFGRRGPPGA---------KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISG 2249
              G RGPPG          KG  G PG  GF+GEQG +G  GPAGP G PG  GE+G  G
Sbjct: 433  FPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRG 492

Query: 2250 PRGSGGAAGA---PGERGRTGPLGRKGEPGEPGPKGGIGNRGP------RGETGDDGRDG 2300
             RG  G  G    PGERG  G  G  G+ G  GPKG  G RGP      +G  GD GR G
Sbjct: 493  ARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPG 552

Query: 2301 V----GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGR---------RGNSG 2347
                 G+ G  G+ G+ G  G  GP G PGE G  G  GP+G RG+         +G +G
Sbjct: 553  EPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANG 612

Query: 2348 PPGIVGQKGDPGYP---------------GPAGPKGNRGDSIDQCA 2378
             PG  G+KG PG P               GP GP G  G+  +Q A
Sbjct: 613  EPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 658



 Score =  276 bits (706), Expect = 2e-73
 Identities = 174/408 (42%), Positives = 203/408 (49%), Gaps = 72/408 (17%)

Query: 2038 GQRGDRGPIGSIGPKGI------PGEDGYRGYPGDEGGPGERGPPGV---NGTQGFQGCP 2088
            G  G+RGP G  GPKG       PGE G  G  G  G PG+ GP G    +G  G  G P
Sbjct: 528  GAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRP 587

Query: 2089 GQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER 2148
            G  G +G+RG PG  G  G  G +G  G+ G+KGLPG+ G +G PG+ G+ G  G  G  
Sbjct: 588  GPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPA 647

Query: 2149 GDVGIRGDPGNPGQDSQE-----RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRR 2203
            G  G RG+ G PG    +      GP GE G  G  GVPG  G PG  G  G+ G  G R
Sbjct: 648  GPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGER 707

Query: 2204 GPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAA------ 2257
            G PGA+G +G  G PG  G  G +GA GPAGP G  G  G QG+ G RG+ G A      
Sbjct: 708  GSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDR 767

Query: 2258 ---------GAPGE---RGRTGPL---------GRKGEPGEPGPKGGIGNRGPRGETGD- 2295
                     GAPG+   RG TGP+         G KGE G PGP G  G RG  GE G+ 
Sbjct: 768  GDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGET 827

Query: 2296 --------------DGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIR 2340
                          DG+ G  G +G  G+KG+ G PG  GP G PG  G  G TGPKG R
Sbjct: 828  GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 887

Query: 2341 GRR------------GNSGPPGIVGQKGDPGYPGPA---GPKGNRGDS 2373
            G +            G  GPPG  G  G PG PGP+   GPKG RGDS
Sbjct: 888  GAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDS 935



 Score =  271 bits (692), Expect = 1e-71
 Identities = 159/351 (45%), Positives = 182/351 (51%), Gaps = 25/351 (7%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G  G +G  G +GPKG  GE G  G+ G++G  GE GP G       QG PG  G +G R
Sbjct: 438  GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGP------QGAPGPAGEEGKR 491

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGS---SGEKGNPGRRGDKGPRGEKGERGDVGIR 2154
            G  GE G VG IG  G  G  G++G PG    +G KG PG RG  G  G KG  GD G  
Sbjct: 492  GARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRP 551

Query: 2155 GDPGNPGQD--SQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNG-----GF----GRR 2203
            G+PG PG    +   G  G  G +GP G PG DG PG PG  G  G     GF    G  
Sbjct: 552  GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 611

Query: 2204 GPPGAKGNKGGPGQPGFEG---EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAP 2260
            G PG  G KG PG PG  G   + G  GA GP GPAGP G  GEQG  GP G  G  G P
Sbjct: 612  GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP 671

Query: 2261 GERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPG 2320
            G  G  G  G +G PGE G  G +G RG RG  G+  R   G++G +G +G  G PG  G
Sbjct: 672  GPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE--RGSPGAQGLQGPRGLPGTPGTDG 729

Query: 2321 PKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
            PKG  G  G  G  GP G++G  G  G  GI G KGD G  G  GP+G  G
Sbjct: 730  PKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG 780



 Score =  270 bits (691), Expect = 1e-71
 Identities = 168/401 (41%), Positives = 198/401 (49%), Gaps = 69/401 (17%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G +G+ GP G+ GP+G  G  G  G PG  G  G  G PG +G  G +G  G  G+ G+ 
Sbjct: 372  GAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAP 431

Query: 2098 GFPGE---------------KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142
            GFPG                KG+ GE G+ G  GE G KG PG +G +G PG  G++G R
Sbjct: 432  GFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKR 491

Query: 2143 GEKGERGDVGI------RGDPGN---PGQDSQ--------ERGPKGETGDLGPMGVPGRD 2185
            G +GE G VG       RG PGN   PGQD          ERGP G  G  G  G PGR 
Sbjct: 492  GARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRP 551

Query: 2186 GVPGGPGE------------------TGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTR 2227
            G PG PG                   +G  G  GR GPPG +G +G PG  GF G +G  
Sbjct: 552  GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 611

Query: 2228 GAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNR 2287
            G  G AG  G PG  G +G+ G  G  GAAG PG     GP G +GE G PGP G  G  
Sbjct: 612  GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP---AGPAGERGEQGAPGPSGFQGLP 668

Query: 2288 GPRGETGDDGRDG-------VGSEGRRGKKGERGFPGY---PGPKGNPGEPGLNGTTGPK 2337
            GP G  G+ G+ G        G+ G  G +GERGFPG    PG +G  G  GL GT G  
Sbjct: 669  GPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTD 728

Query: 2338 GIRGRRGNSGPPGIVGQKGDPGYPGP------AGPKGNRGD 2372
            G +G  G +GPPG  G  G  G PG       AGPKG+RGD
Sbjct: 729  GPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 769



 Score =  270 bits (691), Expect = 1e-71
 Identities = 155/367 (42%), Positives = 180/367 (49%), Gaps = 32/367 (8%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G  G  GP G+ G  G  GE G  G  GD G PG +GP G  G QG  G  G +G +G++
Sbjct: 831  GPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQ 890

Query: 2098 GFPGEKG---EVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154
            G PG  G     G +G  G +G  G  G PG SG+ G  G RGD GP G  GE G  G  
Sbjct: 891  GPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPA 950

Query: 2155 GDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGG 2214
            G PG  G+   + GP G  G  GP G+ G+ G+ G PG+ G+ G  G  GP G  G +G 
Sbjct: 951  GPPGEKGEPGDD-GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 1009

Query: 2215 PGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGE 2274
            PG  G  G  G  G  G  GPAG PG  G  G  GP G  GAAG  G+RG TG +G  G 
Sbjct: 1010 PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA 1069

Query: 2275 PG---EPGPKGGIGNRGPRGETGDDGRDG----------------------VGSEGRRGK 2309
            PG    PGP G  G +G RGE G  G  G                       G  G RG 
Sbjct: 1070 PGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGL 1129

Query: 2310 KGERGFPGY---PGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGP 2366
            KG RGF G    PGP G  G+ G +G  GP G RG  G  GP G  G  G PG  GP GP
Sbjct: 1130 KGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGP 1189

Query: 2367 KGNRGDS 2373
            +G  G++
Sbjct: 1190 RGRSGET 1196



 Score =  266 bits (680), Expect = 2e-70
 Identities = 165/408 (40%), Positives = 199/408 (48%), Gaps = 67/408 (16%)

Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQ 2085
            E+   G+    +G +GDRG +G  GP+G PG+DG RG  G  G PG   P G NG +G  
Sbjct: 754  ERGAAGI----AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPG---PAGANGEKGEV 806

Query: 2086 GCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKG----- 2140
            G PG  G  G+RG PGE+GE G  G  G  G  G  G PG+ GE+G  G++GD G     
Sbjct: 807  GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 866

Query: 2141 ----------------PRGEKGERGDVGIRGDPG------------NPGQD-----SQER 2167
                            P+G +G +G  G  G PG            NPG       S + 
Sbjct: 867  GPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKD 926

Query: 2168 GPKGETGDLGPMGVPGRDGV------PGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFE 2221
            GPKG  GD GP G  G  G+      PG  GE G +G  G  GPPG +G  G  G  G  
Sbjct: 927  GPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLP 986

Query: 2222 GEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPK 2281
            G++G RG  G  GP+G PG  G  G SG RG  G  G PG  G  G  GR+G PG  GP 
Sbjct: 987  GQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPP 1046

Query: 2282 G---GIGNRGPRGETGDDGRDGV-------GSEGRRGKKGERGFPGYPGPKGNPGEPGLN 2331
            G     G +G RGETG  G  G        G  G  GK+G+RG  G  GP G  G  G  
Sbjct: 1047 GRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGAR 1106

Query: 2332 GTTGPKGIRGRRGNSGPPGIVGQKGDPGY------PGPAGPKGNRGDS 2373
            G  GP+G RG +G +G PG  G KG  G+      PGP GP G++G S
Sbjct: 1107 GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGAS 1154



 Score =  265 bits (678), Expect = 4e-70
 Identities = 162/396 (40%), Positives = 195/396 (49%), Gaps = 74/396 (18%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G+RG  G  G  GP+G+PG  G     G +G  G  GPPG  G  G QG PG+RG  G  
Sbjct: 705  GERGSPGAQGLQGPRGLPGTPGT---DGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIA 761

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPG------------------------SSGEKGNP 2133
            G  G++G+VGE G +G  G+DG +GL G                        S+G +G P
Sbjct: 762  GPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAP 821

Query: 2134 GRRGDKGPRGE---------------KGERGDVGIRGDPGNPGQDSQERGPKGETGDLGP 2178
            G RG+ GP G                KGE+G+ G +GD G PG     +GP G  G  GP
Sbjct: 822  GERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGP----QGPSGAPGPQGP 877

Query: 2179 MGVPGRDGVPGG---PGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGA------ 2229
             GV G  G  G    PG TG  G  GR GPPG+ GN G PG PG  G+ G +GA      
Sbjct: 878  TGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGP 937

Query: 2230 ---------QGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGE---PGE 2277
                     QGPAGP G  G  G+ G SG  G  G  G  G+RG  G  G++GE   PG 
Sbjct: 938  PGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGL 997

Query: 2278 PGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGP 2336
            PGP G  G +G  G +GD G  G VG  G  G  GE      PG +G+PG  G  G  G 
Sbjct: 998  PGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGE------PGREGSPGADGPPGRDGA 1051

Query: 2337 KGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
             G++G RG +G  G  G  G PG PGPAGP G +GD
Sbjct: 1052 AGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGD 1087



 Score =  265 bits (678), Expect = 4e-70
 Identities = 154/347 (44%), Positives = 180/347 (51%), Gaps = 20/347 (5%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGC----- 2087
            P   +G +G RG  G  G  G PG  G  G PG  G PG  GPPG +G  G +G      
Sbjct: 877  PTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSG 936

Query: 2088 ----PGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRG 2143
                 G+ G++G  G PGEKGE G+ G  G +G  G +GL G  G  G PG+RG++G  G
Sbjct: 937  PPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG 996

Query: 2144 EKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRR 2203
              G  G+ G +G PG  G D    GP G  G  GP G PGR+G PG  G  G++G  G +
Sbjct: 997  LPGPSGEPGKQGAPGASG-DRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVK 1055

Query: 2204 GPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGER 2263
            G  G  G  G PG PG        G+ GPAGP G  G  GE G  GP G  G AGA G +
Sbjct: 1056 GDRGETGAVGAPGAPG------PPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQ 1109

Query: 2264 GRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV----GSEGRRGKKGERGFPGYP 2319
            G  GP G KGE GEPG +G  G+RG  G  G  G  G     G+ G  G  G RG PG  
Sbjct: 1110 GPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPV 1169

Query: 2320 GPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGP 2366
            GP G  G  G+ G  GP G RGR G +GP G  G  G PG PGP GP
Sbjct: 1170 GPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGP 1216



 Score =  263 bits (673), Expect = 2e-69
 Identities = 156/364 (42%), Positives = 186/364 (51%), Gaps = 29/364 (7%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEG------GPGERGPPGVNGTQGFQGCPGQR 2091
            G RG+ G +G IGP G  G  G RG+PG +G       PGERGP G+ G +G  G PG+ 
Sbjct: 492  GARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRP 551

Query: 2092 G------VKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEK 2145
            G       +G  G PG+ G  G++G  G  GEDG  G PG  G +G PG  G  GP+G  
Sbjct: 552  GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 611

Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP 2205
            GE G  G +G PG PG      G  GETG  GP G  G  G  G  G  G +G  G  GP
Sbjct: 612  GEPGKAGEKGLPGAPGLRGLP-GKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGP 670

Query: 2206 PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGE---QGISGPRGSGGAAGAPGE 2262
            PG  G  G PG  G  GE G  G  GP G  G PG  G    QG+ GPRG  G  G  G 
Sbjct: 671  PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGP 730

Query: 2263 RGRTGPLGRKGEPGEPGPKGGIGNRG------PRGETGDDGRDGV-GSEGRRGKKGERGF 2315
            +G +GP G  G  G PG +G  G RG      P+G+ GD G  G  G+ G+ G +G  G 
Sbjct: 731  KGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGP 790

Query: 2316 PGYPGPKGNPGE------PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGN 2369
             G PGP G  GE      PG  G+ G +G  G RG +GPPG  G  G PG  G  G KG 
Sbjct: 791  IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGE 850

Query: 2370 RGDS 2373
            +G++
Sbjct: 851  QGEA 854



 Score =  261 bits (667), Expect = 8e-69
 Identities = 156/361 (43%), Positives = 180/361 (49%), Gaps = 27/361 (7%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDG---------YRGYPGDEGGPGERGPPGVNGTQGFQGCP 2088
            G+ G  GP GS G +G PGE G         + G PG +G PG +G  G  G +G  G P
Sbjct: 804  GEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAP 863

Query: 2089 GQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGE---K 2145
            G +G  G+ G  G  G  G  G  G  G  G  G PG++G  G PG  G+ GP G     
Sbjct: 864  GPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPS 923

Query: 2146 GERGDVGIRGDPGNPGQDSQE--RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRR 2203
            G+ G  G RGD G PG+  +   +GP G  G+ G  G  G  G  G PG  G  G  G  
Sbjct: 924  GKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIV 983

Query: 2204 GPPGAKGNKGGPGQPGFEGEQGTRGA------QGPAGPAGPPGLIGEQGISGPRGSGGAA 2257
            G PG +G +G PG PG  GE G +GA      +GP GP GPPGL G  G  G  GS GA 
Sbjct: 984  GLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGAD 1043

Query: 2258 GAPGERGRTGPLGRKGE------PGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKK 2310
            G PG  G  G  G +GE      PG PGP G  G  GP G+ GD G  G  G  G  G  
Sbjct: 1044 GPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPA 1103

Query: 2311 GERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNR 2370
            G RG  G  GP+G+ GE G  G  G KG RG  G  G PG  G  GD G  GPAGP G R
Sbjct: 1104 GARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPR 1163

Query: 2371 G 2371
            G
Sbjct: 1164 G 1164



 Score =  252 bits (644), Expect = 4e-66
 Identities = 157/364 (43%), Positives = 178/364 (48%), Gaps = 39/364 (10%)

Query: 2038 GQRGDRGPIGSI-GPKGIPGEDG---YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGV 2093
            GQ+G+ G I  I GPKG PG  G    +G  GD G  GE+G PG  G  G  G PG  G 
Sbjct: 104  GQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGP 163

Query: 2094 KGSRGFPGEKGEVGEIGLD---GLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD 2150
             G  G PG  G  G        G D + G   L    G  G  G RG  GP G  G +G 
Sbjct: 164  PGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGF 223

Query: 2151 VGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKG 2210
             G  G+PG P          G +G +GP G PG  G PG  GE GK G  G RGPPG +G
Sbjct: 224  QGNPGEPGEP----------GVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQG 273

Query: 2211 NKGGPGQPGFEGEQGTR---GAQGPAGPAGPPGLIGEQGISGPRGSG---GAAGAPGERG 2264
             +G PG PG  G +G R   G  G  G AG PG+ GE G  G  GS    G  G PGERG
Sbjct: 274  ARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERG 333

Query: 2265 RTGP---LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV----------GSEGRRGKKG 2311
            RTGP    G +G  G+PGP G  G  GP G  G  G  G           G EG +G +G
Sbjct: 334  RTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRG 393

Query: 2312 ERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDP---GYPGPAGPKG 2368
            E G PG PGP G  G PG +G  G KG  G  G +G PG  G +G P   G  GP GPKG
Sbjct: 394  EPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKG 453

Query: 2369 NRGD 2372
              G+
Sbjct: 454  QTGE 457



 Score =  233 bits (593), Expect = 3e-60
 Identities = 140/322 (43%), Positives = 159/322 (49%), Gaps = 12/322 (3%)

Query: 2053 GIPGEDGYRGYPGD-EGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGL 2111
            G PG  G +G PGD +   G +GPPG  G  G QG  G RG KG +G PG +G  GE G 
Sbjct: 98   GQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT 157

Query: 2112 DGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKG 2171
             G  G  G  G PG  G  GN   +   G   EK     +G+   P  P       GP+G
Sbjct: 158  PGNPGPPGPPGPPGPPGLGGNFAAQM-AGGFDEKAGGAQLGVMQGPMGP------MGPRG 210

Query: 2172 ETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQG 2231
              G  G  G  G  G PG PGE G +G  G RGPPG  G  G  G+ G  G+ G RG  G
Sbjct: 211  PPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPG 270

Query: 2232 PAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRG 2291
            P G  G PG  G  G+ G RG  G  GA GE G  G    KGE G PG  G  G  GPRG
Sbjct: 271  PQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGV---KGESGSPGENGSPGPMGPRG 327

Query: 2292 ETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPG 2350
              G+ GR G  G+ G RG  G+ G  G PGP G  G PG  G  G KG  G  G  GP G
Sbjct: 328  LPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEG 387

Query: 2351 IVGQKGDPGYPGPAGPKGNRGD 2372
              G +G+PG PG  GP G  G+
Sbjct: 388  AQGPRGEPGTPGSPGPAGASGN 409



 Score =  171 bits (433), Expect = 1e-41
 Identities = 103/247 (41%), Positives = 121/247 (48%), Gaps = 18/247 (7%)

Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGF- 2084
            ++   G+P    GQRG+RG  G  GP G PG+ G  G  GD G PG  GPPG+ G  G  
Sbjct: 979  QRGIVGLP----GQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEP 1034

Query: 2085 --QGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142
              +G PG  G  G  G  G KG+ GE G  G  G  G  G PG +G  G  G RG+ G +
Sbjct: 1035 GREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQ 1094

Query: 2143 GEKGERGDVGIRG--DPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPG---ETGKN 2197
            G  G  G  G RG   P  P  D  E G  GE G  G  G  G  G+PG PG   + G +
Sbjct: 1095 GPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGAS 1154

Query: 2198 GGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAA 2257
                  GP G  G +G PG  G  G+ G  G  GP GP GP G  GE G +GP G+ G  
Sbjct: 1155 ------GPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP 1208

Query: 2258 GAPGERG 2264
            G PG  G
Sbjct: 1209 GPPGPPG 1215



 Score =  159 bits (403), Expect = 3e-38
 Identities = 103/280 (36%), Positives = 119/280 (42%), Gaps = 77/280 (27%)

Query: 2169 PKGETGDLGPMGVPGRDGVPGGPGETGKNGGF----GRRGPPGA---------------K 2209
            P GE   + P  +    G PG  G+ G+ G      G +GPPG                K
Sbjct: 81   PFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDK 140

Query: 2210 GNKGGPGQPGFEGEQGTRGAQGPAGPAGPPG---------------------------LI 2242
            G KG PG  G +GE GT G  GP GP GPPG                           + 
Sbjct: 141  GEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQ 200

Query: 2243 GEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-- 2300
            G  G  GPRG  G AGAPG +G  G  G  GEPG  GP G  G  GP G+ GDDG  G  
Sbjct: 201  GPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKP 260

Query: 2301 --VGSEGRRGKKGERGFPGYP---------------------------GPKGNPGEPGLN 2331
               G  G  G +G RGFPG P                           G  G+PGE G  
Sbjct: 261  GKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSP 320

Query: 2332 GTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
            G  GP+G+ G RG +GP G  G +G+ G PGPAGP G  G
Sbjct: 321  GPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVG 360



 Score = 80.5 bits (197), Expect = 2e-14
 Identities = 54/140 (38%), Positives = 65/140 (46%), Gaps = 27/140 (19%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G RGD+G  G  G +G+    G+RG+ G +G PG  GP       G QG  G  G  G R
Sbjct: 1113 GPRGDKGEAGEPGERGL---KGHRGFTGLQGLPGPPGP------SGDQGASGPAGPSGPR 1163

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157
            G PG  G           G+DG  G+PG  G  G  GR G+ GP G  G  G  G  G P
Sbjct: 1164 GPPGPVGP---------SGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPP 1214

Query: 2158 GNPGQD--------SQERGP 2169
            G PG D         +E+GP
Sbjct: 1215 G-PGIDMSAFAGLGPREKGP 1233



 Score = 69.7 bits (169), Expect = 4e-11
 Identities = 44/119 (36%), Positives = 53/119 (44%), Gaps = 36/119 (30%)

Query: 2264 GRTGPLGRKGEPGE----PGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYP 2319
            G+ GP G+KGEPG+     GPKG  G +GP            G +G RG +G++G  G P
Sbjct: 98   GQPGPKGQKGEPGDIKDIVGPKGPPGPQGP-----------AGEQGPRGDRGDKGEKGAP 146

Query: 2320 GPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCA 2378
            GP                     RG  G PG  G  G PG PGP GP G  G+   Q A
Sbjct: 147  GP---------------------RGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMA 184



 Score = 33.5 bits (75), Expect = 3.4
 Identities = 18/41 (43%), Positives = 21/41 (51%), Gaps = 10/41 (24%)

Query: 2346 SGPPGIVGQKGDP----------GYPGPAGPKGNRGDSIDQ 2376
            SG PG  GQKG+P          G PGP GP G +G   D+
Sbjct: 97   SGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDR 137


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score =  293 bits (749), Expect = 2e-78
 Identities = 164/373 (43%), Positives = 194/373 (52%), Gaps = 43/373 (11%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096
            +G  G  GP G  G +G PG  G++G PG  G PGE G PG  G  G  G PG  G +G 
Sbjct: 572  AGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGE 631

Query: 2097 RGFPGEKGEVGEIGLDG------LDGEDGDKGLPGSSGE---------KGNPGRRGDKGP 2141
            RGFPGE+G  G  GL G        G DG KG  G +G          +G PG RG  G 
Sbjct: 632  RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 691

Query: 2142 RGEKGERGDVGIRGDPGNPGQDSQE--------------RGPKGETGDLGPMGVPGRDGV 2187
             G KG+RGDVG +G  G PG+D                  G KGE G  GP G  G  G 
Sbjct: 692  AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA 751

Query: 2188 PGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGI 2247
            PG  GETG  G  G  GPPGA G  G  G+ G  G++G  GA GP GP+G PG  G  G+
Sbjct: 752  PGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGV 811

Query: 2248 SGPRGSGGAAGAPGERG------RTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV 2301
            +GP+G+ GA G PG  G      R GP G  G PG PGP G  G  GP+G  GD      
Sbjct: 812  TGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDS----- 866

Query: 2302 GSEGRRGKKGERGFPGYPGPKGNPGE---PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDP 2358
            G  GR G+ G +G  G PG KG PG+    G  G  GP+G+ G+RG  G PG  G++G P
Sbjct: 867  GPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFP 926

Query: 2359 GYPGPAGPKGNRG 2371
            G PGP+G  G +G
Sbjct: 927  GLPGPSGEPGKQG 939



 Score =  290 bits (742), Expect = 2e-77
 Identities = 166/361 (45%), Positives = 189/361 (52%), Gaps = 38/361 (10%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G+ G  GP+G  GP G PG+ G  G  G  G  GERGPPG  G +GF G PG  GVKG R
Sbjct: 162  GEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHR 221

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157
            G+PG  G  GE G  G+ GE G      S GE G+PG  G +G  GE+G  G  G  G  
Sbjct: 222  GYPGLDGAKGEAGAPGVKGESG------SPGENGSPGPMGPRGLPGERGRTGPAGAAGAR 275

Query: 2158 GNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQ 2217
            GN GQ     GP G  G +GP G PG  G PG  GE G  G    RGP GA+G +G PG 
Sbjct: 276  GNDGQP----GPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGA---RGPEGAQGPRGEPGT 328

Query: 2218 PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGE 2277
            PG  G  G  G  G  G  G  G  G  GI+G  G  G  G PG +G TGPLG KG+ GE
Sbjct: 329  PGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGE 388

Query: 2278 PGPKGGIGNRGPRGETGDDGRDG----VGSEGRRGKKGE------------------RGF 2315
            PG  G  G +GP+GE G  G  G     G EG+RG +GE                  RGF
Sbjct: 389  PGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGF 448

Query: 2316 P---GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
            P   G  GPKG PGE G +G  GPKG  G  G  G PG+ G +G  G PG AGP+G  G 
Sbjct: 449  PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGP 508

Query: 2373 S 2373
            S
Sbjct: 509  S 509



 Score =  283 bits (723), Expect = 2e-75
 Identities = 173/406 (42%), Positives = 202/406 (49%), Gaps = 74/406 (18%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGG------------------PGERGPPGV 2078
            +G+ GD GP G +GP G PGEDG  G PG +G                   PG+ G  G+
Sbjct: 494  TGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGL 553

Query: 2079 NGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGD 2138
             G  G +G PG+ G  G+ G PG  G  GE G  G  G  G +GLPG  G  G  G+ GD
Sbjct: 554  PGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGD 613

Query: 2139 K------------GPRGEK---GERGDVGI------RGDPGNPGQDSQERGPKGETGDLG 2177
            +            GPRGE+   GERG  G       RG PG PG D    GPKG +G  G
Sbjct: 614  QGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTD----GPKGASGPAG 669

Query: 2178 PMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAG 2237
            P G  G  G+ G PGE G  G  G +G  G  G KG  G PG +G +G  G  GP GPAG
Sbjct: 670  PPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAG 729

Query: 2238 PPGLIGEQGISGPRGSGGAAGAPGERGRTGP---------------LGRKGEPGEPGPKG 2282
              G  GE G  GP GS GA GAPGERG TGP                G KGE GE G KG
Sbjct: 730  ANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKG 789

Query: 2283 GIGNRGPRGETGDDGRDG-------VGSEGRRGKKGERGFPGY------PGPKGNPGEPG 2329
              G  GP+G +G  G  G        G+ G +G  G  GFPG       PG  GNPG PG
Sbjct: 790  DAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG 849

Query: 2330 LNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSID 2375
              G +G  G +G RG+SGPP   G+ G+PG  GPAGP G +G+  D
Sbjct: 850  PPGPSGKDGPKGARGDSGPP---GRAGEPGLQGPAGPPGEKGEPGD 892



 Score =  279 bits (713), Expect = 4e-74
 Identities = 158/349 (45%), Positives = 180/349 (51%), Gaps = 12/349 (3%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096
            +G  G RG  G  GP G PG  G  G PG  G PG +G  G  G +G +G  G RG  G+
Sbjct: 269  AGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGT 328

Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGD 2156
             G PG  G  G  G DG+ G  G  G PG +G  G PG RG  GP+G  G  G  G  G+
Sbjct: 329  PGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGE 388

Query: 2157 PGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPG---AKGNKG 2213
            PG  G    E+GPKGE G  GP G PG  G  G  G  G+ GG G  GPPG   A GN+G
Sbjct: 389  PGIAGFKG-EQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRG 447

Query: 2214 GPGQPGFEGEQGTRGAQGPAGPAGP------PGLIGEQGISGPRGSGGAAGAPGERGRTG 2267
             PGQ G  G +G  G +GP+G AGP      PG  GE G+ G RG  G  G  G +G+ G
Sbjct: 448  FPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVG 507

Query: 2268 PLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGE 2327
            P G  GE G PGP G  G RG  G  G  G  G  + G  GK GE+G PG PG +G PG+
Sbjct: 508  PSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKG--ANGEPGKAGEKGLPGAPGLRGLPGK 565

Query: 2328 PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQ 2376
             G  G  GP G  G  G  G  G  G  G  G PGP GP G  G   DQ
Sbjct: 566  DGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQ 614



 Score =  276 bits (706), Expect = 2e-73
 Identities = 171/406 (42%), Positives = 200/406 (49%), Gaps = 63/406 (15%)

Query: 2031 GVPCKCSGQRGDRGPIGSIG---PKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGC 2087
            G P K +G+RG  GP G+ G     G+PG  G+RGYPG +G  GE G PGV G  G  G 
Sbjct: 189  GKPGK-AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGE 247

Query: 2088 PGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGE---------KGNPGRRGD 2138
             G  G  G RG PGE+G  G  G  G  G DG  G  G  G           G PG +G+
Sbjct: 248  NGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGE 307

Query: 2139 KGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNG 2198
             GP G +G  G  G RG+PG PG      GP G +G+ G  G+PG  G  G PG  G  G
Sbjct: 308  AGPTGARGPEGAQGPRGEPGTPGSP----GPAGASGNPGTDGIPGAKGSAGAPGIAGAPG 363

Query: 2199 GFGRRGPPGA---------KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISG 2249
              G RGPPG          KG  G PG  GF+GEQG +G  GPAGP G PG  GE+G  G
Sbjct: 364  FPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRG 423

Query: 2250 PRGSGGAAGA---PGERGRTGPLGRKGEPGEPGPKGGIGNRGP------RGETGDDGRDG 2300
             RG  G  G    PGERG  G  G  G+ G  GPKG  G RGP      +G  GD GR G
Sbjct: 424  ARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPG 483

Query: 2301 V----GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGR---------RGNSG 2347
                 G+ G  G+ G+ G  G  GP G PGE G  G  GP+G RG+         +G +G
Sbjct: 484  EPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANG 543

Query: 2348 PPGIVGQKGDPGYP---------------GPAGPKGNRGDSIDQCA 2378
             PG  G+KG PG P               GP GP G  G+  +Q A
Sbjct: 544  EPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 589



 Score =  276 bits (706), Expect = 2e-73
 Identities = 174/408 (42%), Positives = 203/408 (49%), Gaps = 72/408 (17%)

Query: 2038 GQRGDRGPIGSIGPKGI------PGEDGYRGYPGDEGGPGERGPPGV---NGTQGFQGCP 2088
            G  G+RGP G  GPKG       PGE G  G  G  G PG+ GP G    +G  G  G P
Sbjct: 459  GAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRP 518

Query: 2089 GQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER 2148
            G  G +G+RG PG  G  G  G +G  G+ G+KGLPG+ G +G PG+ G+ G  G  G  
Sbjct: 519  GPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPA 578

Query: 2149 GDVGIRGDPGNPGQDSQE-----RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRR 2203
            G  G RG+ G PG    +      GP GE G  G  GVPG  G PG  G  G+ G  G R
Sbjct: 579  GPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGER 638

Query: 2204 GPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAA------ 2257
            G PGA+G +G  G PG  G  G +GA GPAGP G  G  G QG+ G RG+ G A      
Sbjct: 639  GSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDR 698

Query: 2258 ---------GAPGE---RGRTGPL---------GRKGEPGEPGPKGGIGNRGPRGETGD- 2295
                     GAPG+   RG TGP+         G KGE G PGP G  G RG  GE G+ 
Sbjct: 699  GDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGET 758

Query: 2296 --------------DGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIR 2340
                          DG+ G  G +G  G+KG+ G PG  GP G PG  G  G TGPKG R
Sbjct: 759  GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 818

Query: 2341 GRR------------GNSGPPGIVGQKGDPGYPGPA---GPKGNRGDS 2373
            G +            G  GPPG  G  G PG PGP+   GPKG RGDS
Sbjct: 819  GAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDS 866



 Score =  271 bits (692), Expect = 1e-71
 Identities = 159/351 (45%), Positives = 182/351 (51%), Gaps = 25/351 (7%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G  G +G  G +GPKG  GE G  G+ G++G  GE GP G       QG PG  G +G R
Sbjct: 369  GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGP------QGAPGPAGEEGKR 422

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGS---SGEKGNPGRRGDKGPRGEKGERGDVGIR 2154
            G  GE G VG IG  G  G  G++G PG    +G KG PG RG  G  G KG  GD G  
Sbjct: 423  GARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRP 482

Query: 2155 GDPGNPGQD--SQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNG-----GF----GRR 2203
            G+PG PG    +   G  G  G +GP G PG DG PG PG  G  G     GF    G  
Sbjct: 483  GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 542

Query: 2204 GPPGAKGNKGGPGQPGFEG---EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAP 2260
            G PG  G KG PG PG  G   + G  GA GP GPAGP G  GEQG  GP G  G  G P
Sbjct: 543  GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP 602

Query: 2261 GERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPG 2320
            G  G  G  G +G PGE G  G +G RG RG  G+  R   G++G +G +G  G PG  G
Sbjct: 603  GPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE--RGSPGAQGLQGPRGLPGTPGTDG 660

Query: 2321 PKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
            PKG  G  G  G  GP G++G  G  G  GI G KGD G  G  GP+G  G
Sbjct: 661  PKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG 711



 Score =  270 bits (691), Expect = 1e-71
 Identities = 168/401 (41%), Positives = 198/401 (49%), Gaps = 69/401 (17%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G +G+ GP G+ GP+G  G  G  G PG  G  G  G PG +G  G +G  G  G+ G+ 
Sbjct: 303  GAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAP 362

Query: 2098 GFPGE---------------KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142
            GFPG                KG+ GE G+ G  GE G KG PG +G +G PG  G++G R
Sbjct: 363  GFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKR 422

Query: 2143 GEKGERGDVGI------RGDPGN---PGQDSQ--------ERGPKGETGDLGPMGVPGRD 2185
            G +GE G VG       RG PGN   PGQD          ERGP G  G  G  G PGR 
Sbjct: 423  GARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRP 482

Query: 2186 GVPGGPGE------------------TGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTR 2227
            G PG PG                   +G  G  GR GPPG +G +G PG  GF G +G  
Sbjct: 483  GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 542

Query: 2228 GAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNR 2287
            G  G AG  G PG  G +G+ G  G  GAAG PG     GP G +GE G PGP G  G  
Sbjct: 543  GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP---AGPAGERGEQGAPGPSGFQGLP 599

Query: 2288 GPRGETGDDGRDG-------VGSEGRRGKKGERGFPGY---PGPKGNPGEPGLNGTTGPK 2337
            GP G  G+ G+ G        G+ G  G +GERGFPG    PG +G  G  GL GT G  
Sbjct: 600  GPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTD 659

Query: 2338 GIRGRRGNSGPPGIVGQKGDPGYPGP------AGPKGNRGD 2372
            G +G  G +GPPG  G  G  G PG       AGPKG+RGD
Sbjct: 660  GPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 700



 Score =  270 bits (691), Expect = 1e-71
 Identities = 155/367 (42%), Positives = 180/367 (49%), Gaps = 32/367 (8%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G  G  GP G+ G  G  GE G  G  GD G PG +GP G  G QG  G  G +G +G++
Sbjct: 762  GPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQ 821

Query: 2098 GFPGEKG---EVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154
            G PG  G     G +G  G +G  G  G PG SG+ G  G RGD GP G  GE G  G  
Sbjct: 822  GPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPA 881

Query: 2155 GDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGG 2214
            G PG  G+   + GP G  G  GP G+ G+ G+ G PG+ G+ G  G  GP G  G +G 
Sbjct: 882  GPPGEKGEPGDD-GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 940

Query: 2215 PGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGE 2274
            PG  G  G  G  G  G  GPAG PG  G  G  GP G  GAAG  G+RG TG +G  G 
Sbjct: 941  PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA 1000

Query: 2275 PG---EPGPKGGIGNRGPRGETGDDGRDG----------------------VGSEGRRGK 2309
            PG    PGP G  G +G RGE G  G  G                       G  G RG 
Sbjct: 1001 PGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGL 1060

Query: 2310 KGERGFPGY---PGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGP 2366
            KG RGF G    PGP G  G+ G +G  GP G RG  G  GP G  G  G PG  GP GP
Sbjct: 1061 KGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGP 1120

Query: 2367 KGNRGDS 2373
            +G  G++
Sbjct: 1121 RGRSGET 1127



 Score =  266 bits (680), Expect = 2e-70
 Identities = 165/408 (40%), Positives = 199/408 (48%), Gaps = 67/408 (16%)

Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQ 2085
            E+   G+    +G +GDRG +G  GP+G PG+DG RG  G  G PG   P G NG +G  
Sbjct: 685  ERGAAGI----AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPG---PAGANGEKGEV 737

Query: 2086 GCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKG----- 2140
            G PG  G  G+RG PGE+GE G  G  G  G  G  G PG+ GE+G  G++GD G     
Sbjct: 738  GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 797

Query: 2141 ----------------PRGEKGERGDVGIRGDPG------------NPGQD-----SQER 2167
                            P+G +G +G  G  G PG            NPG       S + 
Sbjct: 798  GPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKD 857

Query: 2168 GPKGETGDLGPMGVPGRDGV------PGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFE 2221
            GPKG  GD GP G  G  G+      PG  GE G +G  G  GPPG +G  G  G  G  
Sbjct: 858  GPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLP 917

Query: 2222 GEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPK 2281
            G++G RG  G  GP+G PG  G  G SG RG  G  G PG  G  G  GR+G PG  GP 
Sbjct: 918  GQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPP 977

Query: 2282 G---GIGNRGPRGETGDDGRDGV-------GSEGRRGKKGERGFPGYPGPKGNPGEPGLN 2331
            G     G +G RGETG  G  G        G  G  GK+G+RG  G  GP G  G  G  
Sbjct: 978  GRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGAR 1037

Query: 2332 GTTGPKGIRGRRGNSGPPGIVGQKGDPGY------PGPAGPKGNRGDS 2373
            G  GP+G RG +G +G PG  G KG  G+      PGP GP G++G S
Sbjct: 1038 GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGAS 1085



 Score =  265 bits (678), Expect = 4e-70
 Identities = 162/396 (40%), Positives = 195/396 (49%), Gaps = 74/396 (18%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G+RG  G  G  GP+G+PG  G     G +G  G  GPPG  G  G QG PG+RG  G  
Sbjct: 636  GERGSPGAQGLQGPRGLPGTPGT---DGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIA 692

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPG------------------------SSGEKGNP 2133
            G  G++G+VGE G +G  G+DG +GL G                        S+G +G P
Sbjct: 693  GPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAP 752

Query: 2134 GRRGDKGPRGE---------------KGERGDVGIRGDPGNPGQDSQERGPKGETGDLGP 2178
            G RG+ GP G                KGE+G+ G +GD G PG     +GP G  G  GP
Sbjct: 753  GERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGP----QGPSGAPGPQGP 808

Query: 2179 MGVPGRDGVPGG---PGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGA------ 2229
             GV G  G  G    PG TG  G  GR GPPG+ GN G PG PG  G+ G +GA      
Sbjct: 809  TGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGP 868

Query: 2230 ---------QGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGE---PGE 2277
                     QGPAGP G  G  G+ G SG  G  G  G  G+RG  G  G++GE   PG 
Sbjct: 869  PGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGL 928

Query: 2278 PGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGP 2336
            PGP G  G +G  G +GD G  G VG  G  G  GE      PG +G+PG  G  G  G 
Sbjct: 929  PGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGE------PGREGSPGADGPPGRDGA 982

Query: 2337 KGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
             G++G RG +G  G  G  G PG PGPAGP G +GD
Sbjct: 983  AGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGD 1018



 Score =  265 bits (678), Expect = 4e-70
 Identities = 154/347 (44%), Positives = 180/347 (51%), Gaps = 20/347 (5%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGC----- 2087
            P   +G +G RG  G  G  G PG  G  G PG  G PG  GPPG +G  G +G      
Sbjct: 808  PTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSG 867

Query: 2088 ----PGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRG 2143
                 G+ G++G  G PGEKGE G+ G  G +G  G +GL G  G  G PG+RG++G  G
Sbjct: 868  PPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG 927

Query: 2144 EKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRR 2203
              G  G+ G +G PG  G D    GP G  G  GP G PGR+G PG  G  G++G  G +
Sbjct: 928  LPGPSGEPGKQGAPGASG-DRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVK 986

Query: 2204 GPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGER 2263
            G  G  G  G PG PG        G+ GPAGP G  G  GE G  GP G  G AGA G +
Sbjct: 987  GDRGETGAVGAPGAPG------PPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQ 1040

Query: 2264 GRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV----GSEGRRGKKGERGFPGYP 2319
            G  GP G KGE GEPG +G  G+RG  G  G  G  G     G+ G  G  G RG PG  
Sbjct: 1041 GPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPV 1100

Query: 2320 GPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGP 2366
            GP G  G  G+ G  GP G RGR G +GP G  G  G PG PGP GP
Sbjct: 1101 GPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGP 1147



 Score =  263 bits (673), Expect = 2e-69
 Identities = 156/364 (42%), Positives = 186/364 (51%), Gaps = 29/364 (7%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEG------GPGERGPPGVNGTQGFQGCPGQR 2091
            G RG+ G +G IGP G  G  G RG+PG +G       PGERGP G+ G +G  G PG+ 
Sbjct: 423  GARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRP 482

Query: 2092 G------VKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEK 2145
            G       +G  G PG+ G  G++G  G  GEDG  G PG  G +G PG  G  GP+G  
Sbjct: 483  GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 542

Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP 2205
            GE G  G +G PG PG      G  GETG  GP G  G  G  G  G  G +G  G  GP
Sbjct: 543  GEPGKAGEKGLPGAPGLRGLP-GKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGP 601

Query: 2206 PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGE---QGISGPRGSGGAAGAPGE 2262
            PG  G  G PG  G  GE G  G  GP G  G PG  G    QG+ GPRG  G  G  G 
Sbjct: 602  PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGP 661

Query: 2263 RGRTGPLGRKGEPGEPGPKGGIGNRG------PRGETGDDGRDGV-GSEGRRGKKGERGF 2315
            +G +GP G  G  G PG +G  G RG      P+G+ GD G  G  G+ G+ G +G  G 
Sbjct: 662  KGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGP 721

Query: 2316 PGYPGPKGNPGE------PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGN 2369
             G PGP G  GE      PG  G+ G +G  G RG +GPPG  G  G PG  G  G KG 
Sbjct: 722  IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGE 781

Query: 2370 RGDS 2373
            +G++
Sbjct: 782  QGEA 785



 Score =  261 bits (667), Expect = 8e-69
 Identities = 156/361 (43%), Positives = 180/361 (49%), Gaps = 27/361 (7%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDG---------YRGYPGDEGGPGERGPPGVNGTQGFQGCP 2088
            G+ G  GP GS G +G PGE G         + G PG +G PG +G  G  G +G  G P
Sbjct: 735  GEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAP 794

Query: 2089 GQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGE---K 2145
            G +G  G+ G  G  G  G  G  G  G  G  G PG++G  G PG  G+ GP G     
Sbjct: 795  GPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPS 854

Query: 2146 GERGDVGIRGDPGNPGQDSQE--RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRR 2203
            G+ G  G RGD G PG+  +   +GP G  G+ G  G  G  G  G PG  G  G  G  
Sbjct: 855  GKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIV 914

Query: 2204 GPPGAKGNKGGPGQPGFEGEQGTRGA------QGPAGPAGPPGLIGEQGISGPRGSGGAA 2257
            G PG +G +G PG PG  GE G +GA      +GP GP GPPGL G  G  G  GS GA 
Sbjct: 915  GLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGAD 974

Query: 2258 GAPGERGRTGPLGRKGE------PGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKK 2310
            G PG  G  G  G +GE      PG PGP G  G  GP G+ GD G  G  G  G  G  
Sbjct: 975  GPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPA 1034

Query: 2311 GERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNR 2370
            G RG  G  GP+G+ GE G  G  G KG RG  G  G PG  G  GD G  GPAGP G R
Sbjct: 1035 GARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPR 1094

Query: 2371 G 2371
            G
Sbjct: 1095 G 1095



 Score =  252 bits (644), Expect = 4e-66
 Identities = 157/364 (43%), Positives = 178/364 (48%), Gaps = 39/364 (10%)

Query: 2038 GQRGDRGPIGSI-GPKGIPGEDG---YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGV 2093
            GQ+G+ G I  I GPKG PG  G    +G  GD G  GE+G PG  G  G  G PG  G 
Sbjct: 35   GQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGP 94

Query: 2094 KGSRGFPGEKGEVGEIGLD---GLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD 2150
             G  G PG  G  G        G D + G   L    G  G  G RG  GP G  G +G 
Sbjct: 95   PGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGF 154

Query: 2151 VGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKG 2210
             G  G+PG P          G +G +GP G PG  G PG  GE GK G  G RGPPG +G
Sbjct: 155  QGNPGEPGEP----------GVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQG 204

Query: 2211 NKGGPGQPGFEGEQGTR---GAQGPAGPAGPPGLIGEQGISGPRGSG---GAAGAPGERG 2264
             +G PG PG  G +G R   G  G  G AG PG+ GE G  G  GS    G  G PGERG
Sbjct: 205  ARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERG 264

Query: 2265 RTGP---LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV----------GSEGRRGKKG 2311
            RTGP    G +G  G+PGP G  G  GP G  G  G  G           G EG +G +G
Sbjct: 265  RTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRG 324

Query: 2312 ERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDP---GYPGPAGPKG 2368
            E G PG PGP G  G PG +G  G KG  G  G +G PG  G +G P   G  GP GPKG
Sbjct: 325  EPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKG 384

Query: 2369 NRGD 2372
              G+
Sbjct: 385  QTGE 388



 Score =  231 bits (590), Expect = 7e-60
 Identities = 139/320 (43%), Positives = 158/320 (49%), Gaps = 12/320 (3%)

Query: 2055 PGEDGYRGYPGD-EGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDG 2113
            PG  G +G PGD +   G +GPPG  G  G QG  G RG KG +G PG +G  GE G  G
Sbjct: 31   PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPG 90

Query: 2114 LDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGET 2173
              G  G  G PG  G  GN   +   G   EK     +G+   P  P       GP+G  
Sbjct: 91   NPGPPGPPGPPGPPGLGGNFAAQM-AGGFDEKAGGAQLGVMQGPMGP------MGPRGPP 143

Query: 2174 GDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPA 2233
            G  G  G  G  G PG PGE G +G  G RGPPG  G  G  G+ G  G+ G RG  GP 
Sbjct: 144  GPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 203

Query: 2234 GPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGET 2293
            G  G PG  G  G+ G RG  G  GA GE G  G    KGE G PG  G  G  GPRG  
Sbjct: 204  GARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGV---KGESGSPGENGSPGPMGPRGLP 260

Query: 2294 GDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIV 2352
            G+ GR G  G+ G RG  G+ G  G PGP G  G PG  G  G KG  G  G  GP G  
Sbjct: 261  GERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQ 320

Query: 2353 GQKGDPGYPGPAGPKGNRGD 2372
            G +G+PG PG  GP G  G+
Sbjct: 321  GPRGEPGTPGSPGPAGASGN 340



 Score =  173 bits (439), Expect = 2e-42
 Identities = 106/273 (38%), Positives = 122/273 (44%), Gaps = 68/273 (24%)

Query: 2161 GQDSQERGPKGETGD-------LGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKG 2213
            GQD ++ GPKG+ G+       +GP G PG  G  G  G  G  G  G +G PG +G  G
Sbjct: 25   GQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDG 84

Query: 2214 GPGQPGFEGEQGTRGAQGPAGPAGPPGL------------------------IGEQGISG 2249
             PG P      G  G  GP GP GPPGL                         G  G  G
Sbjct: 85   EPGTP------GNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMG 138

Query: 2250 PRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG----VGSEG 2305
            PRG  G AGAPG +G  G  G  GEPG  GP G  G  GP G+ GDDG  G     G  G
Sbjct: 139  PRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERG 198

Query: 2306 RRGKKGERGFPGYP---------------------------GPKGNPGEPGLNGTTGPKG 2338
              G +G RGFPG P                           G  G+PGE G  G  GP+G
Sbjct: 199  PPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRG 258

Query: 2339 IRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
            + G RG +GP G  G +G+ G PGPAGP G  G
Sbjct: 259  LPGERGRTGPAGAAGARGNDGQPGPAGPPGPVG 291



 Score =  171 bits (433), Expect = 1e-41
 Identities = 103/247 (41%), Positives = 121/247 (48%), Gaps = 18/247 (7%)

Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGF- 2084
            ++   G+P    GQRG+RG  G  GP G PG+ G  G  GD G PG  GPPG+ G  G  
Sbjct: 910  QRGIVGLP----GQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEP 965

Query: 2085 --QGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142
              +G PG  G  G  G  G KG+ GE G  G  G  G  G PG +G  G  G RG+ G +
Sbjct: 966  GREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQ 1025

Query: 2143 GEKGERGDVGIRG--DPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPG---ETGKN 2197
            G  G  G  G RG   P  P  D  E G  GE G  G  G  G  G+PG PG   + G +
Sbjct: 1026 GPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGAS 1085

Query: 2198 GGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAA 2257
                  GP G  G +G PG  G  G+ G  G  GP GP GP G  GE G +GP G+ G  
Sbjct: 1086 ------GPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP 1139

Query: 2258 GAPGERG 2264
            G PG  G
Sbjct: 1140 GPPGPPG 1146



 Score = 80.5 bits (197), Expect = 2e-14
 Identities = 54/140 (38%), Positives = 65/140 (46%), Gaps = 27/140 (19%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G RGD+G  G  G +G+    G+RG+ G +G PG  GP       G QG  G  G  G R
Sbjct: 1044 GPRGDKGEAGEPGERGL---KGHRGFTGLQGLPGPPGP------SGDQGASGPAGPSGPR 1094

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157
            G PG  G           G+DG  G+PG  G  G  GR G+ GP G  G  G  G  G P
Sbjct: 1095 GPPGPVGP---------SGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPP 1145

Query: 2158 GNPGQD--------SQERGP 2169
            G PG D         +E+GP
Sbjct: 1146 G-PGIDMSAFAGLGPREKGP 1164



 Score = 67.4 bits (163), Expect = 2e-10
 Identities = 43/116 (37%), Positives = 51/116 (43%), Gaps = 36/116 (31%)

Query: 2267 GPLGRKGEPGE----PGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPK 2322
            GP G+KGEPG+     GPKG  G +GP            G +G RG +G++G  G PGP 
Sbjct: 32   GPKGQKGEPGDIKDIVGPKGPPGPQGP-----------AGEQGPRGDRGDKGEKGAPGP- 79

Query: 2323 GNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCA 2378
                                RG  G PG  G  G PG PGP GP G  G+   Q A
Sbjct: 80   --------------------RGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMA 115


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  289 bits (739), Expect = 3e-77
 Identities = 170/401 (42%), Positives = 205/401 (51%), Gaps = 71/401 (17%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERG---------------PPGVNGTQ 2082
            G  G++GP G  G  G+PG DG  G+PG EG  GE+G               P GV G  
Sbjct: 721  GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGAD 780

Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142
            G +G  G +G KG  GFPG KG++G  G  G  G+ G +G  G  G KG  G  GD GP 
Sbjct: 781  GVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPS 840

Query: 2143 GEKGERGDVGIRGDPGNPGQDSQERGPKGET---------GDLGPMGVPGRDGVPGGPGE 2193
            G+ GE+G +G+ G PG PG+    +GPKG T         G+ G  GV G+ G  G  G 
Sbjct: 841  GQAGEKGKLGVPGLPGYPGR----QGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP 896

Query: 2194 TGKNGGFGRRGP---PGAKGNKGGPGQPGFEGEQGTRGAQGPA---GPAGPPGLIGE--- 2244
            TG  G  G RGP   PG KG  GG G PG  GE+G +G QGP    GP GPPG  G+   
Sbjct: 897  TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL 956

Query: 2245 ------------QGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGP------------ 2280
                        QG +GP G GG  G  G  G TGP+G +G PG PGP            
Sbjct: 957  PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 1016

Query: 2281 KGGIGNRGPRGETGDDGRDGV----------GSEGRRGKKGERGFPGYPGPKGNPGEPGL 2330
            +G  G+ GP+G +G DG  G+          G++G  G KG  G  G PGP G+PGE G 
Sbjct: 1017 EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGS 1076

Query: 2331 NGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
             GT GP G+ GR G  GPPG  G+KG PG  GP GP G  G
Sbjct: 1077 AGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1117



 Score =  286 bits (731), Expect = 3e-76
 Identities = 164/353 (46%), Positives = 194/353 (54%), Gaps = 20/353 (5%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDG---YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094
            G+ G  GP G +GP+G  GE G    RG+PG  G PGE+G PG  G +G +G PG +G+ 
Sbjct: 970  GKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGIS 1029

Query: 2095 GS------RGFPGEKGEVGEIGLDGLDGEDGDKGLPG---SSGEKGNPGRRGDKGPRGEK 2145
            G       RGFPGE+G  G  G  GL G +G +G PG   S GE+G+ G  G  G  G  
Sbjct: 1030 GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRP 1089

Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP 2205
            G +G  G  G+ G PG+   + GP G  G  GP+G+PG  G  G PGE G  G  G  G 
Sbjct: 1090 GPQGPPGPAGEKGAPGEKGPQ-GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ 1148

Query: 2206 PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE--- 2262
             G+KG+KG  G PG  G QG  GA G AG  G PG  G+QG+ G +G  GA G PG    
Sbjct: 1149 KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP 1208

Query: 2263 ---RGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGY 2318
               +G  GP G KGE G+ GP G  G  GPRG  G +G DG  G  G  G  G  G  G 
Sbjct: 1209 IGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1268

Query: 2319 PGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
            PG  GNPG PG  G  GPKG RG +G +GPPG  G  G  G PG  GPKGN G
Sbjct: 1269 PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPG 1321



 Score =  284 bits (726), Expect = 1e-75
 Identities = 163/384 (42%), Positives = 195/384 (50%), Gaps = 52/384 (13%)

Query: 2038 GQRGDRGPIGSIG---PKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQG---FQGCPGQR 2091
            G  G+ GPIG  G   P G PGE G  G  G EG  G+ GP G++G  G    +G PG+R
Sbjct: 985  GPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGER 1044

Query: 2092 GVKGSR------------------GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNP 2133
            G+ G++                  G PGE+G  G  G  GL G  G +G PG +GEKG P
Sbjct: 1045 GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1104

Query: 2134 GRRGDKGPRGEKGERGDVGI---------------RGDPGNPGQ-----DSQERGPKGET 2173
            G +G +GP G  G +G VG+               +G+ G PGQ     D  E GP G  
Sbjct: 1105 GEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP 1164

Query: 2174 GDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFE---GEQGTRGAQ 2230
            G  GP+G PG  G  G PG  G+ G FG++G  GA+G  G PG  G +   G  G +G  
Sbjct: 1165 GLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGEN 1224

Query: 2231 GPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGE---PGPKGGIGNR 2287
            G  GP GPPG  G +G  GP G+ G  G PG  G  G +G KGEPGE   PGP G  G  
Sbjct: 1225 GDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVG 1284

Query: 2288 GPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSG 2347
            GP+GE G+ G    G  G  G  G +G PG  GPKGNPG  G  G  GP G  G  G  G
Sbjct: 1285 GPKGERGEKGE--AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDG 1342

Query: 2348 PPGIVGQKGDPGYPGPAGPKGNRG 2371
              G  G+ GDPG PGP GP G  G
Sbjct: 1343 VGGDKGEDGDPGQPGPPGPSGEAG 1366



 Score =  283 bits (723), Expect = 2e-75
 Identities = 171/388 (44%), Positives = 200/388 (51%), Gaps = 56/388 (14%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNG---------TQGFQGCP 2088
            GQ+G +G  G  GP G PG  G  G PG  GG GE GP G  G          +GF G P
Sbjct: 1147 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPP 1206

Query: 2089 GQRGVKGSRGFPGEKGEVGEIGL------------DGLDGEDGDKGLPGSSG------EK 2130
            G  G++G  G PGEKGE G++G              G +G DG +G PGS G      EK
Sbjct: 1207 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1266

Query: 2131 GNPGRRGDKGPRGE------KGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGR 2184
            G PG  G+ GP GE      KGERG+ G  G PG  G      G KG  GD GP G PG 
Sbjct: 1267 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP----GAKGPPGDDGPKGNPGP 1322

Query: 2185 DGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGE 2244
             G PG PG  G+ G  G+ G  G KG  G PGQPG  G  G  G  GP G  GPPG  G 
Sbjct: 1323 VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGA 1382

Query: 2245 QGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGE------TGDDGR 2298
            +G  G +G+ G AGA G  G+TGP+G +G  G+PGP+G  G  GP GE       G DG 
Sbjct: 1383 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP 1442

Query: 2299 DG-------VGSEGRRGKKGERGFPGY------PGPKGNPGEPGLNGTTGPKGIRGRRGN 2345
             G        G +G  G KGE+G PG       PG +G  G+ GL GT G  G +G  G 
Sbjct: 1443 PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGI 1502

Query: 2346 SGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373
             GP G +G  G PG PGP GPKGN+G +
Sbjct: 1503 PGPAGPLGPPGPPGLPGPQGPKGNKGST 1530



 Score =  282 bits (722), Expect = 3e-75
 Identities = 172/377 (45%), Positives = 196/377 (51%), Gaps = 35/377 (9%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGD------EGGPGERGPPGVNGTQGFQGCPGQR 2091
            G RG  GP G IG +G+PG  G +G  GD       G PG RGP G NG  G QG PG  
Sbjct: 1198 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV 1257

Query: 2092 GVKGSRGFPGEKGEVG------EIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEK 2145
            G  G  G  GE GE G      E G+ G  GE G+KG  G  G  G PG +G  G  G K
Sbjct: 1258 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK 1317

Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP 2205
            G  G VG  GDPG PG+     G  G  GD G  G PG+ G PG  GE G  G  G+RGP
Sbjct: 1318 GNPGPVGFPGDPGPPGEPGPA-GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGP 1376

Query: 2206 PGA------KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGA 2259
            PGA      +G KG  G+ G EG  G  G  GP GPAG PG  G +GI GP G  G  GA
Sbjct: 1377 PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1436

Query: 2260 PGERGRTGPLGR------KGEPGEPGPKGG---IGNRGPRGETGDDGRDGV-GSEGRRGK 2309
             G+ G  GP+G       KG+PG  G KG    IG  GP GE G+ G  G+ G++G  G 
Sbjct: 1437 AGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGA 1496

Query: 2310 KGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGN 2369
            KG+ G PG  GP G PG PGL G  GPK      GN G  G  GQKGD G PGP G  G 
Sbjct: 1497 KGDGGIPGPAGPLGPPGPPGLPGPQGPK------GNKGSTGPAGQKGDSGLPGPPGSPGP 1550

Query: 2370 RGDSIDQCALIQSIKDK 2386
             G+ I    ++ S K +
Sbjct: 1551 PGEVIQPLPILSSKKTR 1567



 Score =  278 bits (712), Expect = 5e-74
 Identities = 164/366 (44%), Positives = 191/366 (52%), Gaps = 32/366 (8%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096
            SG  G +GP G  GP G  G+ G RG PG +GG G  G PG  G +GF G PG  G KG 
Sbjct: 567  SGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGH 626

Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGD---KGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI 2153
            RG  G +G  G  G DG+ GEDG+   +GLPG +G +G  G RG  G  G+ G  G  G 
Sbjct: 627  RGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP 686

Query: 2154 RGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKG 2213
             G  GN G    E GP G+ G+ GP G+PG  G  G PGE G  G  G  G PGA G  G
Sbjct: 687  PGPKGNMGPQG-EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPG 745

Query: 2214 GPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE----------- 2262
             PG+ G  GE+G  G  GP GP G PG  G +G  G RG  G+ G  GE           
Sbjct: 746  HPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG 805

Query: 2263 ----RGRTGPLGRKGEPGEPGPK---GGIGNRGPRGETGDDGRDGV----GSEGRRGKKG 2311
                RG  G +G +GE G  GPK   G  G+ GP G+ G+ G+ GV    G  GR+G KG
Sbjct: 806  LKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKG 865

Query: 2312 ERGFPGYPGPKGN------PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAG 2365
              GFPG+PG  G        G+PG  G  GP G RG RG  GP G  G KG  G  GP G
Sbjct: 866  STGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPG 925

Query: 2366 PKGNRG 2371
            P G RG
Sbjct: 926  PPGERG 931



 Score =  276 bits (707), Expect = 2e-73
 Identities = 170/387 (43%), Positives = 200/387 (51%), Gaps = 30/387 (7%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPG---DEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094
            G  G+RG  G+ GP G+PG  G +G PG   ++G PGE+GP G  G  G QG  G  G  
Sbjct: 1069 GSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPA 1128

Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKG---------LPGSSGEKGNPGRRGDKGPRGEK 2145
            G  G PGE G+ GEIG  G  G  GDKG         L G  G  G  G  G+ GPRG++
Sbjct: 1129 GPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQ 1188

Query: 2146 G---ERGDVGIRGDPGNPGQDSQER-----GPKGETGDLGPMGVPGRDGVPGGPGETGKN 2197
            G   ++GD G RG PG PG    +      G KGE GD+GPMG PG    PG  G  G N
Sbjct: 1189 GMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP---PGPRGPQGPN 1245

Query: 2198 GGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAA 2257
            G  G +GPPG+ G+ GG G+ G  GE G  G  G AG  GP G  GE+G +GP G+ G  
Sbjct: 1246 GADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP 1305

Query: 2258 GAPGERGRTGPLGRKGE---PGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGER 2313
            GA G  G  GP G  G    PG+PGP G  G  G  G  GD G DG  G  G  G  GE 
Sbjct: 1306 GAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEA 1365

Query: 2314 GFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGI---VGQKGDPGYPGPAGPKGNR 2370
            G PG PG +G PG  G  G  G KG +G  G  GPPG    VG +G  G PGP G +G  
Sbjct: 1366 GPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIP 1425

Query: 2371 GDSIDQCALIQSIKDKCPCCYGPLECP 2397
            G   +Q     + +D  P   GP   P
Sbjct: 1426 GPVGEQGLPGAAGQDGPPGPMGPPGLP 1452



 Score =  276 bits (706), Expect = 2e-73
 Identities = 155/340 (45%), Positives = 186/340 (54%), Gaps = 27/340 (7%)

Query: 2047 GSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEV 2106
            G  GP G+ G  G  G PG  G  GE G PG  G +G QG PG  G  G RG PG  G  
Sbjct: 541  GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 600

Query: 2107 GEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE 2166
            G  G  G  G+ G  GLPG  G+KG+   RG++GP+G  G  GD G+RG+ G       E
Sbjct: 601  GMPGEPGAKGDRGFDGLPGLPGDKGH---RGERGPQGPPGPPGDDGMRGEDG-------E 650

Query: 2167 RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGT 2226
             GP+G  G+ GP G+ G  G PG PG+ G  G  G  GP G  G +G PG PG +G  G 
Sbjct: 651  IGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 710

Query: 2227 RGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGN 2286
            +G  GP GP GPPG  G QG  G  G  GA G PG  G+ G  G KG  G PGP+G IG 
Sbjct: 711  QGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGY 770

Query: 2287 RGPRGETGDDGRDGVGSEGRRGKKGERGFPGY------PGPKGNPGEPGLNGTTGPKGIR 2340
             GPRG  G DG  G+  +G +G+KGE GFPG+       G +G  G+ G  G  GP+G +
Sbjct: 771  PGPRGVKGADGVRGL--KGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPK 828

Query: 2341 GRRGNSGPPGIVGQKGD---------PGYPGPAGPKGNRG 2371
            GR G +G PG  GQ G+         PGYPG  GPKG+ G
Sbjct: 829  GRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTG 868



 Score =  266 bits (681), Expect = 2e-70
 Identities = 165/388 (42%), Positives = 190/388 (48%), Gaps = 54/388 (13%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G +G  GP G  GP G  GE G  G PG  G PG +GP G  G  GF G  G++G +G  
Sbjct: 826  GPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA 885

Query: 2098 GFPGEKGEVGEIG------LDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR------GEK 2145
            G PG +G+ G  G        G  G+ G KG  G  G  G PG RG +GP+      G K
Sbjct: 886  GKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPK 945

Query: 2146 GERGDVGIRGDPGNPGQDSQER--------------GPKGETGDLGPMGVPGRDGVPGGP 2191
            G  G  G  G PG+PGQ  +                GP+G TG+ GP+G  G  G PG P
Sbjct: 946  GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 1005

Query: 2192 GE------TGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQ---------GPAGPA 2236
            GE       GK G  G  GP G  G  G  G  GF GE+G  GAQ         GP GP 
Sbjct: 1006 GEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPP 1065

Query: 2237 GPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDD 2296
            GP G  GE+G +G  G  G  G PG +G  GP G KG PGE GP+G  G  G +G  G  
Sbjct: 1066 GPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLP 1125

Query: 2297 GRDG-VGSEGRRGKKGERGFPGYPGPKGN------PGEPGLNGTTGPKGIRGRRGNSGP- 2348
            G  G  GS G  G KGE G PG  G KG+      PG PGL G  G  GI G  G  GP 
Sbjct: 1126 GPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPR 1185

Query: 2349 --PGIVGQKGDP---GYPGPAGPKGNRG 2371
               G+ GQKGD    G+PGP GP G +G
Sbjct: 1186 GQQGMFGQKGDEGARGFPGPPGPIGLQG 1213



 Score =  262 bits (670), Expect = 3e-69
 Identities = 156/351 (44%), Positives = 186/351 (52%), Gaps = 19/351 (5%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGD---EGGPGERGPPGVNGTQGFQGCPGQRGVK 2094
            G +G RG  G  GP G PG+DG RG  G+    G PGE GP G+ G +G  G PGQ G+ 
Sbjct: 622  GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 681

Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154
            G  G PG KG +G  G  G  G+ G+ G  G  G +G  G  G+KGP+G+ G  G  G  
Sbjct: 682  GVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 741

Query: 2155 GDPGNPGQDSQ--ERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP---PGAK 2209
            G PG+PG++ Q  E+G  G  G  GP+G PG  GV G  G  G  G  G +G    PG K
Sbjct: 742  GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 801

Query: 2210 GNKGGPGQPGFEGEQGTRGAQGPAGP---AGPPGLIGEQGISGPRGSGGAAGAPGERGRT 2266
            G+ G  G  G  G+ G RG  GP GP   AGP G  G  G +G +G  G  G PG  GR 
Sbjct: 802  GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQ 861

Query: 2267 GPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGN-- 2324
            GP G  G PG PG  G  G RG  G+ G  G+   G  G RG +G RG  G PGPKG   
Sbjct: 862  GPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR--GPTGPRGSRGARGPTGKPGPKGTSG 919

Query: 2325 ----PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
                PG PG  G  GP+G  G  G  GPPG  G+ G PG+PG  G  G +G
Sbjct: 920  GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 970



 Score =  261 bits (666), Expect = 1e-68
 Identities = 164/386 (42%), Positives = 197/386 (51%), Gaps = 40/386 (10%)

Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIG------------PKGIPGEDGYRGYPGDEG----- 2068
            EK   GVP    G  G +GP GS G             +G+ G+ G RG  G  G     
Sbjct: 845  EKGKLGVP-GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSR 903

Query: 2069 ---GP-GERGPPGVNGTQGFQGCPGQRGVKGSR---GFPGEKGEVGEIGLDGLDGEDGDK 2121
               GP G+ GP G +G  G  G PG+RG +G +   GFPG KG  G  G DGL G  G +
Sbjct: 904  GARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQR 963

Query: 2122 GLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE-----RGPKGETGDL 2176
            G  G  G+ G PG  G  GP+G  GE G +G RG PG PG   ++      G +G  GD 
Sbjct: 964  GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 1023

Query: 2177 GPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPA 2236
            GP G+ G+DG  G  G  G+ G  G +G PG KG +G  G PG  G  G RG+ G AGP 
Sbjct: 1024 GPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPI 1083

Query: 2237 GPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDD 2296
            G PG  G Q   GP G  G  GAPGE+G  GP GR G  G  G  G  G  G  GE GD 
Sbjct: 1084 GLPGRPGPQ---GPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1140

Query: 2297 GRDG-VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
            G  G  G +G +G KGE G PG PG +G  G PG+ G  G  G RG++G  G  G  G +
Sbjct: 1141 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1200

Query: 2356 GDPGYPGP------AGPKGNRGDSID 2375
            G PG PGP       GP G +G++ D
Sbjct: 1201 GFPGPPGPIGLQGLPGPPGEKGENGD 1226



 Score =  233 bits (595), Expect = 2e-60
 Identities = 144/350 (41%), Positives = 172/350 (49%), Gaps = 33/350 (9%)

Query: 2044 GPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK--------- 2094
            GP G  GP GI G  G +G  G  G PG+RGPPG  G  G  G PG  G           
Sbjct: 454  GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGG 513

Query: 2095 -GSRG--FPGEKGEVGEI---GLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER 2148
             GS+G     ++ +   I       L G  G  GL G  G  G PG  G KG  G+ G +
Sbjct: 514  DGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ 573

Query: 2149 GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208
            G  G++G PG          P G+ G  G  G  G  G+PG PG  G  G  G  G PG 
Sbjct: 574  GPRGVQGPPG----------PTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 623

Query: 2209 KGNKG--GP-GQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGR 2265
            KG++G  GP G PG  G+ G RG  G  GP G PG  G +G+ GPRG+ GA G PG  G 
Sbjct: 624  KGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV 683

Query: 2266 TGPLGRKGE---PGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPK 2322
             GP G KG     GEPGP G  GN GP+G  G  G   +G  G +G +G+ G  G PG  
Sbjct: 684  DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGP--IGPPGEKGPQGKPGLAGLPGAD 741

Query: 2323 GNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
            G PG PG  G +G KG  G  G  GP G  G +G  G  G  G KG++G+
Sbjct: 742  GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 791



 Score =  219 bits (559), Expect = 3e-56
 Identities = 142/353 (40%), Positives = 167/353 (47%), Gaps = 51/353 (14%)

Query: 2048 SIGPKGIPGEDGYRGYPGD-EGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEV 2106
            SI   G  GE G +G P   E G    GPPG  G  G  G PG +G  G  G PG++G  
Sbjct: 427  SINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPP 486

Query: 2107 GEIGLDGLDGEDGDKG----LPGSSGEKGNPGR--------------------RGDKGPR 2142
            G  GL G DG  G  G    LP   G  G+ G                     RG  GP 
Sbjct: 487  GRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPM 546

Query: 2143 GEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGR 2202
            G  G  G VG  G  G  G+ S + GP+G  G  GP   PG  G PG  G  G +GG G 
Sbjct: 547  GLTGRPGPVGGPGSSGAKGE-SGDPGPQGPRGVQGP---PGPTGKPGKRGRPGADGGRGM 602

Query: 2203 RGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE 2262
             G PGAKG++G  G PG  G++G RG +GP GP GPP                  G  G 
Sbjct: 603  PGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP------------------GDDGM 644

Query: 2263 RGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGP 2321
            RG  G +G +G PGE GP+G +G RG  G  G  G  GV G  G +G  G +G PG PG 
Sbjct: 645  RGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQ 704

Query: 2322 KGNPGEPGLNGTTGPKGIRGRRGNSGPPGIV---GQKGDPGYPGPAGPKGNRG 2371
            +GNPG  GL G  GP G  G +G  G PG+    G  G PG+PG  G  G +G
Sbjct: 705  QGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 757



 Score =  208 bits (530), Expect = 6e-53
 Identities = 117/275 (42%), Positives = 146/275 (53%), Gaps = 17/275 (6%)

Query: 2027 KACCGVPCKCSGQRGDRGPIGSIGP---KGIPGEDGYRGYPGDEGGPGERGPPG------ 2077
            +A  G P    G++G+ GP G+ GP   KG PG+DG +G PG  G PG+ GPPG      
Sbjct: 1280 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAG 1339

Query: 2078 ---VNGTQGFQGCPGQRGV---KGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKG 2131
               V G +G  G PGQ G     G  G PG  G+ G  G  G +G  G+KG  G +G +G
Sbjct: 1340 QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEG 1399

Query: 2132 NPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE--RGPKGETGDLGPMGVPGRDGVPG 2189
             PG+ G  GP+G  G+ G  G+RG PG  G+       G  G  G +GP G+PG  G PG
Sbjct: 1400 PPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPG 1459

Query: 2190 GPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISG 2249
              GE G  G  G  GPPG +G KG  G PG +G  G +G  G  GPAGP G  G  G+ G
Sbjct: 1460 SKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPG 1519

Query: 2250 PRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGI 2284
            P+G  G  G+ G  G+ G  G  G PG PGP G +
Sbjct: 1520 PQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1554



 Score =  186 bits (473), Expect = 2e-46
 Identities = 131/333 (39%), Positives = 155/333 (46%), Gaps = 26/333 (7%)

Query: 2057 EDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPG--EKGEVGEIGLDGL 2114
            ED     P +E GPG   P   + T+      G  G KG +G P   E G + E G  G 
Sbjct: 402  EDKPTSPPNEEFGPGV--PAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVE-GPPGP 458

Query: 2115 DGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNP-------GQDSQER 2167
             G  G  G PG  G  G PG  GD+GP G  G  G  G+ G PG         G D   +
Sbjct: 459  AGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGS-K 517

Query: 2168 GPKGETGDLGPMGV--PGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQG 2225
            GP     +     +    R  + G PG  G  G   R GP G  G+ G  G+ G  G QG
Sbjct: 518  GPTISAQEAQAQAILQQARIALRGPPGPMGLTG---RPGPVGGPGSSGAKGESGDPGPQG 574

Query: 2226 TRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERG---RTGPLGRKGEPGEPGPKG 2282
             RG QGP GP G PG  G  G  G RG  G  GA G+RG     G  G KG  GE GP+G
Sbjct: 575  PRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQG 634

Query: 2283 GIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGR 2342
              G  G  G  G+DG   +G  G  G+ G RG  G  G  G PG+PG+ G  GP G +G 
Sbjct: 635  PPGPPGDDGMRGEDGE--IGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGN 692

Query: 2343 RGNSGPPGIVGQKGDP---GYPGPAGPKGNRGD 2372
             G  G PG  GQ+G+P   G PGP GP G  G+
Sbjct: 693  MGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGE 725



 Score =  158 bits (399), Expect = 9e-38
 Identities = 100/240 (41%), Positives = 120/240 (50%), Gaps = 17/240 (7%)

Query: 2140 GPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGG 2199
            G  GEKG++G+  +  +PG         GP G  G  G MG PG  G  G PG+ G  G 
Sbjct: 432  GAYGEKGQKGEPAVV-EPG-----MLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGP 485

Query: 2200 FGRRGPPGAKGNKGGPGQ----PGFEGEQGTRGAQGPAGPAGPPGLIGEQGIS--GPRGS 2253
             GR G PGA G  G PG     P   G  G++G    A  A    ++ +  I+  GP G 
Sbjct: 486  PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGP 545

Query: 2254 GGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGER 2313
             G  G PG  G  G  G KGE G+PGP+G  G +GP G TG  G+      GR G  G R
Sbjct: 546  MGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGK-----RGRPGADGGR 600

Query: 2314 GFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373
            G PG PG KG+ G  GL G  G KG RG RG  GPPG  G  G  G  G  GP+G  G++
Sbjct: 601  GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 660


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  289 bits (739), Expect = 3e-77
 Identities = 170/401 (42%), Positives = 205/401 (51%), Gaps = 71/401 (17%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERG---------------PPGVNGTQ 2082
            G  G++GP G  G  G+PG DG  G+PG EG  GE+G               P GV G  
Sbjct: 670  GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGAD 729

Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142
            G +G  G +G KG  GFPG KG++G  G  G  G+ G +G  G  G KG  G  GD GP 
Sbjct: 730  GVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPS 789

Query: 2143 GEKGERGDVGIRGDPGNPGQDSQERGPKGET---------GDLGPMGVPGRDGVPGGPGE 2193
            G+ GE+G +G+ G PG PG+    +GPKG T         G+ G  GV G+ G  G  G 
Sbjct: 790  GQAGEKGKLGVPGLPGYPGR----QGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP 845

Query: 2194 TGKNGGFGRRGP---PGAKGNKGGPGQPGFEGEQGTRGAQGPA---GPAGPPGLIGE--- 2244
            TG  G  G RGP   PG KG  GG G PG  GE+G +G QGP    GP GPPG  G+   
Sbjct: 846  TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL 905

Query: 2245 ------------QGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGP------------ 2280
                        QG +GP G GG  G  G  G TGP+G +G PG PGP            
Sbjct: 906  PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 965

Query: 2281 KGGIGNRGPRGETGDDGRDGV----------GSEGRRGKKGERGFPGYPGPKGNPGEPGL 2330
            +G  G+ GP+G +G DG  G+          G++G  G KG  G  G PGP G+PGE G 
Sbjct: 966  EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGS 1025

Query: 2331 NGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
             GT GP G+ GR G  GPPG  G+KG PG  GP GP G  G
Sbjct: 1026 AGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1066



 Score =  286 bits (731), Expect = 3e-76
 Identities = 164/353 (46%), Positives = 194/353 (54%), Gaps = 20/353 (5%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDG---YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094
            G+ G  GP G +GP+G  GE G    RG+PG  G PGE+G PG  G +G +G PG +G+ 
Sbjct: 919  GKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGIS 978

Query: 2095 GS------RGFPGEKGEVGEIGLDGLDGEDGDKGLPG---SSGEKGNPGRRGDKGPRGEK 2145
            G       RGFPGE+G  G  G  GL G +G +G PG   S GE+G+ G  G  G  G  
Sbjct: 979  GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRP 1038

Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP 2205
            G +G  G  G+ G PG+   + GP G  G  GP+G+PG  G  G PGE G  G  G  G 
Sbjct: 1039 GPQGPPGPAGEKGAPGEKGPQ-GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ 1097

Query: 2206 PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE--- 2262
             G+KG+KG  G PG  G QG  GA G AG  G PG  G+QG+ G +G  GA G PG    
Sbjct: 1098 KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP 1157

Query: 2263 ---RGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGY 2318
               +G  GP G KGE G+ GP G  G  GPRG  G +G DG  G  G  G  G  G  G 
Sbjct: 1158 IGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1217

Query: 2319 PGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
            PG  GNPG PG  G  GPKG RG +G +GPPG  G  G  G PG  GPKGN G
Sbjct: 1218 PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPG 1270



 Score =  284 bits (726), Expect = 1e-75
 Identities = 163/384 (42%), Positives = 195/384 (50%), Gaps = 52/384 (13%)

Query: 2038 GQRGDRGPIGSIG---PKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQG---FQGCPGQR 2091
            G  G+ GPIG  G   P G PGE G  G  G EG  G+ GP G++G  G    +G PG+R
Sbjct: 934  GPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGER 993

Query: 2092 GVKGSR------------------GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNP 2133
            G+ G++                  G PGE+G  G  G  GL G  G +G PG +GEKG P
Sbjct: 994  GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1053

Query: 2134 GRRGDKGPRGEKGERGDVGI---------------RGDPGNPGQ-----DSQERGPKGET 2173
            G +G +GP G  G +G VG+               +G+ G PGQ     D  E GP G  
Sbjct: 1054 GEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP 1113

Query: 2174 GDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFE---GEQGTRGAQ 2230
            G  GP+G PG  G  G PG  G+ G FG++G  GA+G  G PG  G +   G  G +G  
Sbjct: 1114 GLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGEN 1173

Query: 2231 GPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGE---PGPKGGIGNR 2287
            G  GP GPPG  G +G  GP G+ G  G PG  G  G +G KGEPGE   PGP G  G  
Sbjct: 1174 GDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVG 1233

Query: 2288 GPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSG 2347
            GP+GE G+ G    G  G  G  G +G PG  GPKGNPG  G  G  GP G  G  G  G
Sbjct: 1234 GPKGERGEKGE--AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDG 1291

Query: 2348 PPGIVGQKGDPGYPGPAGPKGNRG 2371
              G  G+ GDPG PGP GP G  G
Sbjct: 1292 VGGDKGEDGDPGQPGPPGPSGEAG 1315



 Score =  283 bits (723), Expect = 2e-75
 Identities = 171/388 (44%), Positives = 200/388 (51%), Gaps = 56/388 (14%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNG---------TQGFQGCP 2088
            GQ+G +G  G  GP G PG  G  G PG  GG GE GP G  G          +GF G P
Sbjct: 1096 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPP 1155

Query: 2089 GQRGVKGSRGFPGEKGEVGEIGL------------DGLDGEDGDKGLPGSSG------EK 2130
            G  G++G  G PGEKGE G++G              G +G DG +G PGS G      EK
Sbjct: 1156 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1215

Query: 2131 GNPGRRGDKGPRGE------KGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGR 2184
            G PG  G+ GP GE      KGERG+ G  G PG  G      G KG  GD GP G PG 
Sbjct: 1216 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP----GAKGPPGDDGPKGNPGP 1271

Query: 2185 DGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGE 2244
             G PG PG  G+ G  G+ G  G KG  G PGQPG  G  G  G  GP G  GPPG  G 
Sbjct: 1272 VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGA 1331

Query: 2245 QGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGE------TGDDGR 2298
            +G  G +G+ G AGA G  G+TGP+G +G  G+PGP+G  G  GP GE       G DG 
Sbjct: 1332 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP 1391

Query: 2299 DG-------VGSEGRRGKKGERGFPGY------PGPKGNPGEPGLNGTTGPKGIRGRRGN 2345
             G        G +G  G KGE+G PG       PG +G  G+ GL GT G  G +G  G 
Sbjct: 1392 PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGI 1451

Query: 2346 SGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373
             GP G +G  G PG PGP GPKGN+G +
Sbjct: 1452 PGPAGPLGPPGPPGLPGPQGPKGNKGST 1479



 Score =  282 bits (722), Expect = 3e-75
 Identities = 172/377 (45%), Positives = 196/377 (51%), Gaps = 35/377 (9%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGD------EGGPGERGPPGVNGTQGFQGCPGQR 2091
            G RG  GP G IG +G+PG  G +G  GD       G PG RGP G NG  G QG PG  
Sbjct: 1147 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV 1206

Query: 2092 GVKGSRGFPGEKGEVG------EIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEK 2145
            G  G  G  GE GE G      E G+ G  GE G+KG  G  G  G PG +G  G  G K
Sbjct: 1207 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK 1266

Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP 2205
            G  G VG  GDPG PG+     G  G  GD G  G PG+ G PG  GE G  G  G+RGP
Sbjct: 1267 GNPGPVGFPGDPGPPGEPGPA-GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGP 1325

Query: 2206 PGA------KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGA 2259
            PGA      +G KG  G+ G EG  G  G  GP GPAG PG  G +GI GP G  G  GA
Sbjct: 1326 PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1385

Query: 2260 PGERGRTGPLGR------KGEPGEPGPKGG---IGNRGPRGETGDDGRDGV-GSEGRRGK 2309
             G+ G  GP+G       KG+PG  G KG    IG  GP GE G+ G  G+ G++G  G 
Sbjct: 1386 AGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGA 1445

Query: 2310 KGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGN 2369
            KG+ G PG  GP G PG PGL G  GPK      GN G  G  GQKGD G PGP G  G 
Sbjct: 1446 KGDGGIPGPAGPLGPPGPPGLPGPQGPK------GNKGSTGPAGQKGDSGLPGPPGSPGP 1499

Query: 2370 RGDSIDQCALIQSIKDK 2386
             G+ I    ++ S K +
Sbjct: 1500 PGEVIQPLPILSSKKTR 1516



 Score =  278 bits (712), Expect = 5e-74
 Identities = 164/366 (44%), Positives = 191/366 (52%), Gaps = 32/366 (8%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096
            SG  G +GP G  GP G  G+ G RG PG +GG G  G PG  G +GF G PG  G KG 
Sbjct: 516  SGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGH 575

Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGD---KGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI 2153
            RG  G +G  G  G DG+ GEDG+   +GLPG +G +G  G RG  G  G+ G  G  G 
Sbjct: 576  RGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP 635

Query: 2154 RGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKG 2213
             G  GN G    E GP G+ G+ GP G+PG  G  G PGE G  G  G  G PGA G  G
Sbjct: 636  PGPKGNMGPQG-EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPG 694

Query: 2214 GPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE----------- 2262
             PG+ G  GE+G  G  GP GP G PG  G +G  G RG  G+ G  GE           
Sbjct: 695  HPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG 754

Query: 2263 ----RGRTGPLGRKGEPGEPGPK---GGIGNRGPRGETGDDGRDGV----GSEGRRGKKG 2311
                RG  G +G +GE G  GPK   G  G+ GP G+ G+ G+ GV    G  GR+G KG
Sbjct: 755  LKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKG 814

Query: 2312 ERGFPGYPGPKGN------PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAG 2365
              GFPG+PG  G        G+PG  G  GP G RG RG  GP G  G KG  G  GP G
Sbjct: 815  STGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPG 874

Query: 2366 PKGNRG 2371
            P G RG
Sbjct: 875  PPGERG 880



 Score =  276 bits (707), Expect = 2e-73
 Identities = 170/387 (43%), Positives = 200/387 (51%), Gaps = 30/387 (7%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPG---DEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094
            G  G+RG  G+ GP G+PG  G +G PG   ++G PGE+GP G  G  G QG  G  G  
Sbjct: 1018 GSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPA 1077

Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKG---------LPGSSGEKGNPGRRGDKGPRGEK 2145
            G  G PGE G+ GEIG  G  G  GDKG         L G  G  G  G  G+ GPRG++
Sbjct: 1078 GPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQ 1137

Query: 2146 G---ERGDVGIRGDPGNPGQDSQER-----GPKGETGDLGPMGVPGRDGVPGGPGETGKN 2197
            G   ++GD G RG PG PG    +      G KGE GD+GPMG PG    PG  G  G N
Sbjct: 1138 GMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP---PGPRGPQGPN 1194

Query: 2198 GGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAA 2257
            G  G +GPPG+ G+ GG G+ G  GE G  G  G AG  GP G  GE+G +GP G+ G  
Sbjct: 1195 GADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP 1254

Query: 2258 GAPGERGRTGPLGRKGE---PGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGER 2313
            GA G  G  GP G  G    PG+PGP G  G  G  G  GD G DG  G  G  G  GE 
Sbjct: 1255 GAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEA 1314

Query: 2314 GFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGI---VGQKGDPGYPGPAGPKGNR 2370
            G PG PG +G PG  G  G  G KG +G  G  GPPG    VG +G  G PGP G +G  
Sbjct: 1315 GPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIP 1374

Query: 2371 GDSIDQCALIQSIKDKCPCCYGPLECP 2397
            G   +Q     + +D  P   GP   P
Sbjct: 1375 GPVGEQGLPGAAGQDGPPGPMGPPGLP 1401



 Score =  276 bits (706), Expect = 2e-73
 Identities = 155/340 (45%), Positives = 186/340 (54%), Gaps = 27/340 (7%)

Query: 2047 GSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEV 2106
            G  GP G+ G  G  G PG  G  GE G PG  G +G QG PG  G  G RG PG  G  
Sbjct: 490  GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 549

Query: 2107 GEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE 2166
            G  G  G  G+ G  GLPG  G+KG+   RG++GP+G  G  GD G+RG+ G       E
Sbjct: 550  GMPGEPGAKGDRGFDGLPGLPGDKGH---RGERGPQGPPGPPGDDGMRGEDG-------E 599

Query: 2167 RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGT 2226
             GP+G  G+ GP G+ G  G PG PG+ G  G  G  GP G  G +G PG PG +G  G 
Sbjct: 600  IGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 659

Query: 2227 RGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGN 2286
            +G  GP GP GPPG  G QG  G  G  GA G PG  G+ G  G KG  G PGP+G IG 
Sbjct: 660  QGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGY 719

Query: 2287 RGPRGETGDDGRDGVGSEGRRGKKGERGFPGY------PGPKGNPGEPGLNGTTGPKGIR 2340
             GPRG  G DG  G+  +G +G+KGE GFPG+       G +G  G+ G  G  GP+G +
Sbjct: 720  PGPRGVKGADGVRGL--KGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPK 777

Query: 2341 GRRGNSGPPGIVGQKGD---------PGYPGPAGPKGNRG 2371
            GR G +G PG  GQ G+         PGYPG  GPKG+ G
Sbjct: 778  GRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTG 817



 Score =  266 bits (681), Expect = 2e-70
 Identities = 165/388 (42%), Positives = 190/388 (48%), Gaps = 54/388 (13%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G +G  GP G  GP G  GE G  G PG  G PG +GP G  G  GF G  G++G +G  
Sbjct: 775  GPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA 834

Query: 2098 GFPGEKGEVGEIG------LDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR------GEK 2145
            G PG +G+ G  G        G  G+ G KG  G  G  G PG RG +GP+      G K
Sbjct: 835  GKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPK 894

Query: 2146 GERGDVGIRGDPGNPGQDSQER--------------GPKGETGDLGPMGVPGRDGVPGGP 2191
            G  G  G  G PG+PGQ  +                GP+G TG+ GP+G  G  G PG P
Sbjct: 895  GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 954

Query: 2192 GE------TGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQ---------GPAGPA 2236
            GE       GK G  G  GP G  G  G  G  GF GE+G  GAQ         GP GP 
Sbjct: 955  GEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPP 1014

Query: 2237 GPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDD 2296
            GP G  GE+G +G  G  G  G PG +G  GP G KG PGE GP+G  G  G +G  G  
Sbjct: 1015 GPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLP 1074

Query: 2297 GRDG-VGSEGRRGKKGERGFPGYPGPKGN------PGEPGLNGTTGPKGIRGRRGNSGP- 2348
            G  G  GS G  G KGE G PG  G KG+      PG PGL G  G  GI G  G  GP 
Sbjct: 1075 GPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPR 1134

Query: 2349 --PGIVGQKGDP---GYPGPAGPKGNRG 2371
               G+ GQKGD    G+PGP GP G +G
Sbjct: 1135 GQQGMFGQKGDEGARGFPGPPGPIGLQG 1162



 Score =  262 bits (670), Expect = 3e-69
 Identities = 156/351 (44%), Positives = 186/351 (52%), Gaps = 19/351 (5%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGD---EGGPGERGPPGVNGTQGFQGCPGQRGVK 2094
            G +G RG  G  GP G PG+DG RG  G+    G PGE GP G+ G +G  G PGQ G+ 
Sbjct: 571  GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 630

Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154
            G  G PG KG +G  G  G  G+ G+ G  G  G +G  G  G+KGP+G+ G  G  G  
Sbjct: 631  GVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 690

Query: 2155 GDPGNPGQDSQ--ERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP---PGAK 2209
            G PG+PG++ Q  E+G  G  G  GP+G PG  GV G  G  G  G  G +G    PG K
Sbjct: 691  GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 750

Query: 2210 GNKGGPGQPGFEGEQGTRGAQGPAGP---AGPPGLIGEQGISGPRGSGGAAGAPGERGRT 2266
            G+ G  G  G  G+ G RG  GP GP   AGP G  G  G +G +G  G  G PG  GR 
Sbjct: 751  GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQ 810

Query: 2267 GPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGN-- 2324
            GP G  G PG PG  G  G RG  G+ G  G+   G  G RG +G RG  G PGPKG   
Sbjct: 811  GPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR--GPTGPRGSRGARGPTGKPGPKGTSG 868

Query: 2325 ----PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
                PG PG  G  GP+G  G  G  GPPG  G+ G PG+PG  G  G +G
Sbjct: 869  GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 919



 Score =  261 bits (666), Expect = 1e-68
 Identities = 164/386 (42%), Positives = 197/386 (51%), Gaps = 40/386 (10%)

Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIG------------PKGIPGEDGYRGYPGDEG----- 2068
            EK   GVP    G  G +GP GS G             +G+ G+ G RG  G  G     
Sbjct: 794  EKGKLGVP-GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSR 852

Query: 2069 ---GP-GERGPPGVNGTQGFQGCPGQRGVKGSR---GFPGEKGEVGEIGLDGLDGEDGDK 2121
               GP G+ GP G +G  G  G PG+RG +G +   GFPG KG  G  G DGL G  G +
Sbjct: 853  GARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQR 912

Query: 2122 GLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE-----RGPKGETGDL 2176
            G  G  G+ G PG  G  GP+G  GE G +G RG PG PG   ++      G +G  GD 
Sbjct: 913  GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 972

Query: 2177 GPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPA 2236
            GP G+ G+DG  G  G  G+ G  G +G PG KG +G  G PG  G  G RG+ G AGP 
Sbjct: 973  GPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPI 1032

Query: 2237 GPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDD 2296
            G PG  G Q   GP G  G  GAPGE+G  GP GR G  G  G  G  G  G  GE GD 
Sbjct: 1033 GLPGRPGPQ---GPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1089

Query: 2297 GRDG-VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
            G  G  G +G +G KGE G PG PG +G  G PG+ G  G  G RG++G  G  G  G +
Sbjct: 1090 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1149

Query: 2356 GDPGYPGP------AGPKGNRGDSID 2375
            G PG PGP       GP G +G++ D
Sbjct: 1150 GFPGPPGPIGLQGLPGPPGEKGENGD 1175



 Score =  233 bits (595), Expect = 2e-60
 Identities = 144/350 (41%), Positives = 172/350 (49%), Gaps = 33/350 (9%)

Query: 2044 GPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK--------- 2094
            GP G  GP GI G  G +G  G  G PG+RGPPG  G  G  G PG  G           
Sbjct: 403  GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGG 462

Query: 2095 -GSRG--FPGEKGEVGEI---GLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER 2148
             GS+G     ++ +   I       L G  G  GL G  G  G PG  G KG  G+ G +
Sbjct: 463  DGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ 522

Query: 2149 GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208
            G  G++G PG          P G+ G  G  G  G  G+PG PG  G  G  G  G PG 
Sbjct: 523  GPRGVQGPPG----------PTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 572

Query: 2209 KGNKG--GP-GQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGR 2265
            KG++G  GP G PG  G+ G RG  G  GP G PG  G +G+ GPRG+ GA G PG  G 
Sbjct: 573  KGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV 632

Query: 2266 TGPLGRKGE---PGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPK 2322
             GP G KG     GEPGP G  GN GP+G  G  G   +G  G +G +G+ G  G PG  
Sbjct: 633  DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGP--IGPPGEKGPQGKPGLAGLPGAD 690

Query: 2323 GNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
            G PG PG  G +G KG  G  G  GP G  G +G  G  G  G KG++G+
Sbjct: 691  GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 740



 Score =  219 bits (559), Expect = 3e-56
 Identities = 142/353 (40%), Positives = 167/353 (47%), Gaps = 51/353 (14%)

Query: 2048 SIGPKGIPGEDGYRGYPGD-EGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEV 2106
            SI   G  GE G +G P   E G    GPPG  G  G  G PG +G  G  G PG++G  
Sbjct: 376  SINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPP 435

Query: 2107 GEIGLDGLDGEDGDKG----LPGSSGEKGNPGR--------------------RGDKGPR 2142
            G  GL G DG  G  G    LP   G  G+ G                     RG  GP 
Sbjct: 436  GRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPM 495

Query: 2143 GEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGR 2202
            G  G  G VG  G  G  G+ S + GP+G  G  GP   PG  G PG  G  G +GG G 
Sbjct: 496  GLTGRPGPVGGPGSSGAKGE-SGDPGPQGPRGVQGP---PGPTGKPGKRGRPGADGGRGM 551

Query: 2203 RGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE 2262
             G PGAKG++G  G PG  G++G RG +GP GP GPP                  G  G 
Sbjct: 552  PGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP------------------GDDGM 593

Query: 2263 RGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGP 2321
            RG  G +G +G PGE GP+G +G RG  G  G  G  GV G  G +G  G +G PG PG 
Sbjct: 594  RGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQ 653

Query: 2322 KGNPGEPGLNGTTGPKGIRGRRGNSGPPGIV---GQKGDPGYPGPAGPKGNRG 2371
            +GNPG  GL G  GP G  G +G  G PG+    G  G PG+PG  G  G +G
Sbjct: 654  QGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 706



 Score =  208 bits (530), Expect = 6e-53
 Identities = 117/275 (42%), Positives = 146/275 (53%), Gaps = 17/275 (6%)

Query: 2027 KACCGVPCKCSGQRGDRGPIGSIGP---KGIPGEDGYRGYPGDEGGPGERGPPG------ 2077
            +A  G P    G++G+ GP G+ GP   KG PG+DG +G PG  G PG+ GPPG      
Sbjct: 1229 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAG 1288

Query: 2078 ---VNGTQGFQGCPGQRGV---KGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKG 2131
               V G +G  G PGQ G     G  G PG  G+ G  G  G +G  G+KG  G +G +G
Sbjct: 1289 QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEG 1348

Query: 2132 NPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE--RGPKGETGDLGPMGVPGRDGVPG 2189
             PG+ G  GP+G  G+ G  G+RG PG  G+       G  G  G +GP G+PG  G PG
Sbjct: 1349 PPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPG 1408

Query: 2190 GPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISG 2249
              GE G  G  G  GPPG +G KG  G PG +G  G +G  G  GPAGP G  G  G+ G
Sbjct: 1409 SKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPG 1468

Query: 2250 PRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGI 2284
            P+G  G  G+ G  G+ G  G  G PG PGP G +
Sbjct: 1469 PQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1503



 Score =  186 bits (473), Expect = 2e-46
 Identities = 131/333 (39%), Positives = 155/333 (46%), Gaps = 26/333 (7%)

Query: 2057 EDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPG--EKGEVGEIGLDGL 2114
            ED     P +E GPG   P   + T+      G  G KG +G P   E G + E G  G 
Sbjct: 351  EDKPTSPPNEEFGPGV--PAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVE-GPPGP 407

Query: 2115 DGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNP-------GQDSQER 2167
             G  G  G PG  G  G PG  GD+GP G  G  G  G+ G PG         G D   +
Sbjct: 408  AGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGS-K 466

Query: 2168 GPKGETGDLGPMGV--PGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQG 2225
            GP     +     +    R  + G PG  G  G   R GP G  G+ G  G+ G  G QG
Sbjct: 467  GPTISAQEAQAQAILQQARIALRGPPGPMGLTG---RPGPVGGPGSSGAKGESGDPGPQG 523

Query: 2226 TRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERG---RTGPLGRKGEPGEPGPKG 2282
             RG QGP GP G PG  G  G  G RG  G  GA G+RG     G  G KG  GE GP+G
Sbjct: 524  PRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQG 583

Query: 2283 GIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGR 2342
              G  G  G  G+DG   +G  G  G+ G RG  G  G  G PG+PG+ G  GP G +G 
Sbjct: 584  PPGPPGDDGMRGEDGE--IGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGN 641

Query: 2343 RGNSGPPGIVGQKGDP---GYPGPAGPKGNRGD 2372
             G  G PG  GQ+G+P   G PGP GP G  G+
Sbjct: 642  MGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGE 674



 Score =  158 bits (399), Expect = 9e-38
 Identities = 100/240 (41%), Positives = 120/240 (50%), Gaps = 17/240 (7%)

Query: 2140 GPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGG 2199
            G  GEKG++G+  +  +PG         GP G  G  G MG PG  G  G PG+ G  G 
Sbjct: 381  GAYGEKGQKGEPAVV-EPG-----MLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGP 434

Query: 2200 FGRRGPPGAKGNKGGPGQ----PGFEGEQGTRGAQGPAGPAGPPGLIGEQGIS--GPRGS 2253
             GR G PGA G  G PG     P   G  G++G    A  A    ++ +  I+  GP G 
Sbjct: 435  PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGP 494

Query: 2254 GGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGER 2313
             G  G PG  G  G  G KGE G+PGP+G  G +GP G TG  G+      GR G  G R
Sbjct: 495  MGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGK-----RGRPGADGGR 549

Query: 2314 GFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373
            G PG PG KG+ G  GL G  G KG RG RG  GPPG  G  G  G  G  GP+G  G++
Sbjct: 550  GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 609


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  289 bits (739), Expect = 3e-77
 Identities = 170/401 (42%), Positives = 205/401 (51%), Gaps = 71/401 (17%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERG---------------PPGVNGTQ 2082
            G  G++GP G  G  G+PG DG  G+PG EG  GE+G               P GV G  
Sbjct: 709  GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGAD 768

Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142
            G +G  G +G KG  GFPG KG++G  G  G  G+ G +G  G  G KG  G  GD GP 
Sbjct: 769  GVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPS 828

Query: 2143 GEKGERGDVGIRGDPGNPGQDSQERGPKGET---------GDLGPMGVPGRDGVPGGPGE 2193
            G+ GE+G +G+ G PG PG+    +GPKG T         G+ G  GV G+ G  G  G 
Sbjct: 829  GQAGEKGKLGVPGLPGYPGR----QGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP 884

Query: 2194 TGKNGGFGRRGP---PGAKGNKGGPGQPGFEGEQGTRGAQGPA---GPAGPPGLIGE--- 2244
            TG  G  G RGP   PG KG  GG G PG  GE+G +G QGP    GP GPPG  G+   
Sbjct: 885  TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL 944

Query: 2245 ------------QGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGP------------ 2280
                        QG +GP G GG  G  G  G TGP+G +G PG PGP            
Sbjct: 945  PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 1004

Query: 2281 KGGIGNRGPRGETGDDGRDGV----------GSEGRRGKKGERGFPGYPGPKGNPGEPGL 2330
            +G  G+ GP+G +G DG  G+          G++G  G KG  G  G PGP G+PGE G 
Sbjct: 1005 EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGS 1064

Query: 2331 NGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
             GT GP G+ GR G  GPPG  G+KG PG  GP GP G  G
Sbjct: 1065 AGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1105



 Score =  286 bits (731), Expect = 3e-76
 Identities = 164/353 (46%), Positives = 194/353 (54%), Gaps = 20/353 (5%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDG---YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094
            G+ G  GP G +GP+G  GE G    RG+PG  G PGE+G PG  G +G +G PG +G+ 
Sbjct: 958  GKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGIS 1017

Query: 2095 GS------RGFPGEKGEVGEIGLDGLDGEDGDKGLPG---SSGEKGNPGRRGDKGPRGEK 2145
            G       RGFPGE+G  G  G  GL G +G +G PG   S GE+G+ G  G  G  G  
Sbjct: 1018 GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRP 1077

Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP 2205
            G +G  G  G+ G PG+   + GP G  G  GP+G+PG  G  G PGE G  G  G  G 
Sbjct: 1078 GPQGPPGPAGEKGAPGEKGPQ-GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ 1136

Query: 2206 PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE--- 2262
             G+KG+KG  G PG  G QG  GA G AG  G PG  G+QG+ G +G  GA G PG    
Sbjct: 1137 KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP 1196

Query: 2263 ---RGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGY 2318
               +G  GP G KGE G+ GP G  G  GPRG  G +G DG  G  G  G  G  G  G 
Sbjct: 1197 IGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1256

Query: 2319 PGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
            PG  GNPG PG  G  GPKG RG +G +GPPG  G  G  G PG  GPKGN G
Sbjct: 1257 PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPG 1309



 Score =  284 bits (726), Expect = 1e-75
 Identities = 163/384 (42%), Positives = 195/384 (50%), Gaps = 52/384 (13%)

Query: 2038 GQRGDRGPIGSIG---PKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQG---FQGCPGQR 2091
            G  G+ GPIG  G   P G PGE G  G  G EG  G+ GP G++G  G    +G PG+R
Sbjct: 973  GPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGER 1032

Query: 2092 GVKGSR------------------GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNP 2133
            G+ G++                  G PGE+G  G  G  GL G  G +G PG +GEKG P
Sbjct: 1033 GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1092

Query: 2134 GRRGDKGPRGEKGERGDVGI---------------RGDPGNPGQ-----DSQERGPKGET 2173
            G +G +GP G  G +G VG+               +G+ G PGQ     D  E GP G  
Sbjct: 1093 GEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP 1152

Query: 2174 GDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFE---GEQGTRGAQ 2230
            G  GP+G PG  G  G PG  G+ G FG++G  GA+G  G PG  G +   G  G +G  
Sbjct: 1153 GLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGEN 1212

Query: 2231 GPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGE---PGPKGGIGNR 2287
            G  GP GPPG  G +G  GP G+ G  G PG  G  G +G KGEPGE   PGP G  G  
Sbjct: 1213 GDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVG 1272

Query: 2288 GPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSG 2347
            GP+GE G+ G    G  G  G  G +G PG  GPKGNPG  G  G  GP G  G  G  G
Sbjct: 1273 GPKGERGEKGE--AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDG 1330

Query: 2348 PPGIVGQKGDPGYPGPAGPKGNRG 2371
              G  G+ GDPG PGP GP G  G
Sbjct: 1331 VGGDKGEDGDPGQPGPPGPSGEAG 1354



 Score =  283 bits (723), Expect = 2e-75
 Identities = 171/388 (44%), Positives = 200/388 (51%), Gaps = 56/388 (14%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNG---------TQGFQGCP 2088
            GQ+G +G  G  GP G PG  G  G PG  GG GE GP G  G          +GF G P
Sbjct: 1135 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPP 1194

Query: 2089 GQRGVKGSRGFPGEKGEVGEIGL------------DGLDGEDGDKGLPGSSG------EK 2130
            G  G++G  G PGEKGE G++G              G +G DG +G PGS G      EK
Sbjct: 1195 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1254

Query: 2131 GNPGRRGDKGPRGE------KGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGR 2184
            G PG  G+ GP GE      KGERG+ G  G PG  G      G KG  GD GP G PG 
Sbjct: 1255 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP----GAKGPPGDDGPKGNPGP 1310

Query: 2185 DGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGE 2244
             G PG PG  G+ G  G+ G  G KG  G PGQPG  G  G  G  GP G  GPPG  G 
Sbjct: 1311 VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGA 1370

Query: 2245 QGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGE------TGDDGR 2298
            +G  G +G+ G AGA G  G+TGP+G +G  G+PGP+G  G  GP GE       G DG 
Sbjct: 1371 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP 1430

Query: 2299 DG-------VGSEGRRGKKGERGFPGY------PGPKGNPGEPGLNGTTGPKGIRGRRGN 2345
             G        G +G  G KGE+G PG       PG +G  G+ GL GT G  G +G  G 
Sbjct: 1431 PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGI 1490

Query: 2346 SGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373
             GP G +G  G PG PGP GPKGN+G +
Sbjct: 1491 PGPAGPLGPPGPPGLPGPQGPKGNKGST 1518



 Score =  282 bits (722), Expect = 3e-75
 Identities = 172/377 (45%), Positives = 196/377 (51%), Gaps = 35/377 (9%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGD------EGGPGERGPPGVNGTQGFQGCPGQR 2091
            G RG  GP G IG +G+PG  G +G  GD       G PG RGP G NG  G QG PG  
Sbjct: 1186 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV 1245

Query: 2092 GVKGSRGFPGEKGEVG------EIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEK 2145
            G  G  G  GE GE G      E G+ G  GE G+KG  G  G  G PG +G  G  G K
Sbjct: 1246 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK 1305

Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP 2205
            G  G VG  GDPG PG+     G  G  GD G  G PG+ G PG  GE G  G  G+RGP
Sbjct: 1306 GNPGPVGFPGDPGPPGEPGPA-GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGP 1364

Query: 2206 PGA------KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGA 2259
            PGA      +G KG  G+ G EG  G  G  GP GPAG PG  G +GI GP G  G  GA
Sbjct: 1365 PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1424

Query: 2260 PGERGRTGPLGR------KGEPGEPGPKGG---IGNRGPRGETGDDGRDGV-GSEGRRGK 2309
             G+ G  GP+G       KG+PG  G KG    IG  GP GE G+ G  G+ G++G  G 
Sbjct: 1425 AGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGA 1484

Query: 2310 KGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGN 2369
            KG+ G PG  GP G PG PGL G  GPK      GN G  G  GQKGD G PGP G  G 
Sbjct: 1485 KGDGGIPGPAGPLGPPGPPGLPGPQGPK------GNKGSTGPAGQKGDSGLPGPPGSPGP 1538

Query: 2370 RGDSIDQCALIQSIKDK 2386
             G+ I    ++ S K +
Sbjct: 1539 PGEVIQPLPILSSKKTR 1555



 Score =  278 bits (712), Expect = 5e-74
 Identities = 164/366 (44%), Positives = 191/366 (52%), Gaps = 32/366 (8%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096
            SG  G +GP G  GP G  G+ G RG PG +GG G  G PG  G +GF G PG  G KG 
Sbjct: 555  SGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGH 614

Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGD---KGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI 2153
            RG  G +G  G  G DG+ GEDG+   +GLPG +G +G  G RG  G  G+ G  G  G 
Sbjct: 615  RGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP 674

Query: 2154 RGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKG 2213
             G  GN G    E GP G+ G+ GP G+PG  G  G PGE G  G  G  G PGA G  G
Sbjct: 675  PGPKGNMGPQG-EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPG 733

Query: 2214 GPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE----------- 2262
             PG+ G  GE+G  G  GP GP G PG  G +G  G RG  G+ G  GE           
Sbjct: 734  HPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG 793

Query: 2263 ----RGRTGPLGRKGEPGEPGPK---GGIGNRGPRGETGDDGRDGV----GSEGRRGKKG 2311
                RG  G +G +GE G  GPK   G  G+ GP G+ G+ G+ GV    G  GR+G KG
Sbjct: 794  LKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKG 853

Query: 2312 ERGFPGYPGPKGN------PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAG 2365
              GFPG+PG  G        G+PG  G  GP G RG RG  GP G  G KG  G  GP G
Sbjct: 854  STGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPG 913

Query: 2366 PKGNRG 2371
            P G RG
Sbjct: 914  PPGERG 919



 Score =  276 bits (707), Expect = 2e-73
 Identities = 170/387 (43%), Positives = 200/387 (51%), Gaps = 30/387 (7%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPG---DEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094
            G  G+RG  G+ GP G+PG  G +G PG   ++G PGE+GP G  G  G QG  G  G  
Sbjct: 1057 GSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPA 1116

Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKG---------LPGSSGEKGNPGRRGDKGPRGEK 2145
            G  G PGE G+ GEIG  G  G  GDKG         L G  G  G  G  G+ GPRG++
Sbjct: 1117 GPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQ 1176

Query: 2146 G---ERGDVGIRGDPGNPGQDSQER-----GPKGETGDLGPMGVPGRDGVPGGPGETGKN 2197
            G   ++GD G RG PG PG    +      G KGE GD+GPMG PG    PG  G  G N
Sbjct: 1177 GMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP---PGPRGPQGPN 1233

Query: 2198 GGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAA 2257
            G  G +GPPG+ G+ GG G+ G  GE G  G  G AG  GP G  GE+G +GP G+ G  
Sbjct: 1234 GADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP 1293

Query: 2258 GAPGERGRTGPLGRKGE---PGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGER 2313
            GA G  G  GP G  G    PG+PGP G  G  G  G  GD G DG  G  G  G  GE 
Sbjct: 1294 GAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEA 1353

Query: 2314 GFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGI---VGQKGDPGYPGPAGPKGNR 2370
            G PG PG +G PG  G  G  G KG +G  G  GPPG    VG +G  G PGP G +G  
Sbjct: 1354 GPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIP 1413

Query: 2371 GDSIDQCALIQSIKDKCPCCYGPLECP 2397
            G   +Q     + +D  P   GP   P
Sbjct: 1414 GPVGEQGLPGAAGQDGPPGPMGPPGLP 1440



 Score =  276 bits (706), Expect = 2e-73
 Identities = 155/340 (45%), Positives = 186/340 (54%), Gaps = 27/340 (7%)

Query: 2047 GSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEV 2106
            G  GP G+ G  G  G PG  G  GE G PG  G +G QG PG  G  G RG PG  G  
Sbjct: 529  GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 588

Query: 2107 GEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE 2166
            G  G  G  G+ G  GLPG  G+KG+   RG++GP+G  G  GD G+RG+ G       E
Sbjct: 589  GMPGEPGAKGDRGFDGLPGLPGDKGH---RGERGPQGPPGPPGDDGMRGEDG-------E 638

Query: 2167 RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGT 2226
             GP+G  G+ GP G+ G  G PG PG+ G  G  G  GP G  G +G PG PG +G  G 
Sbjct: 639  IGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 698

Query: 2227 RGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGN 2286
            +G  GP GP GPPG  G QG  G  G  GA G PG  G+ G  G KG  G PGP+G IG 
Sbjct: 699  QGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGY 758

Query: 2287 RGPRGETGDDGRDGVGSEGRRGKKGERGFPGY------PGPKGNPGEPGLNGTTGPKGIR 2340
             GPRG  G DG  G+  +G +G+KGE GFPG+       G +G  G+ G  G  GP+G +
Sbjct: 759  PGPRGVKGADGVRGL--KGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPK 816

Query: 2341 GRRGNSGPPGIVGQKGD---------PGYPGPAGPKGNRG 2371
            GR G +G PG  GQ G+         PGYPG  GPKG+ G
Sbjct: 817  GRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTG 856



 Score =  266 bits (681), Expect = 2e-70
 Identities = 165/388 (42%), Positives = 190/388 (48%), Gaps = 54/388 (13%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G +G  GP G  GP G  GE G  G PG  G PG +GP G  G  GF G  G++G +G  
Sbjct: 814  GPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA 873

Query: 2098 GFPGEKGEVGEIG------LDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR------GEK 2145
            G PG +G+ G  G        G  G+ G KG  G  G  G PG RG +GP+      G K
Sbjct: 874  GKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPK 933

Query: 2146 GERGDVGIRGDPGNPGQDSQER--------------GPKGETGDLGPMGVPGRDGVPGGP 2191
            G  G  G  G PG+PGQ  +                GP+G TG+ GP+G  G  G PG P
Sbjct: 934  GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 993

Query: 2192 GE------TGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQ---------GPAGPA 2236
            GE       GK G  G  GP G  G  G  G  GF GE+G  GAQ         GP GP 
Sbjct: 994  GEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPP 1053

Query: 2237 GPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDD 2296
            GP G  GE+G +G  G  G  G PG +G  GP G KG PGE GP+G  G  G +G  G  
Sbjct: 1054 GPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLP 1113

Query: 2297 GRDG-VGSEGRRGKKGERGFPGYPGPKGN------PGEPGLNGTTGPKGIRGRRGNSGP- 2348
            G  G  GS G  G KGE G PG  G KG+      PG PGL G  G  GI G  G  GP 
Sbjct: 1114 GPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPR 1173

Query: 2349 --PGIVGQKGDP---GYPGPAGPKGNRG 2371
               G+ GQKGD    G+PGP GP G +G
Sbjct: 1174 GQQGMFGQKGDEGARGFPGPPGPIGLQG 1201



 Score =  262 bits (670), Expect = 3e-69
 Identities = 156/351 (44%), Positives = 186/351 (52%), Gaps = 19/351 (5%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGD---EGGPGERGPPGVNGTQGFQGCPGQRGVK 2094
            G +G RG  G  GP G PG+DG RG  G+    G PGE GP G+ G +G  G PGQ G+ 
Sbjct: 610  GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 669

Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154
            G  G PG KG +G  G  G  G+ G+ G  G  G +G  G  G+KGP+G+ G  G  G  
Sbjct: 670  GVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 729

Query: 2155 GDPGNPGQDSQ--ERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP---PGAK 2209
            G PG+PG++ Q  E+G  G  G  GP+G PG  GV G  G  G  G  G +G    PG K
Sbjct: 730  GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 789

Query: 2210 GNKGGPGQPGFEGEQGTRGAQGPAGP---AGPPGLIGEQGISGPRGSGGAAGAPGERGRT 2266
            G+ G  G  G  G+ G RG  GP GP   AGP G  G  G +G +G  G  G PG  GR 
Sbjct: 790  GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQ 849

Query: 2267 GPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGN-- 2324
            GP G  G PG PG  G  G RG  G+ G  G+   G  G RG +G RG  G PGPKG   
Sbjct: 850  GPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR--GPTGPRGSRGARGPTGKPGPKGTSG 907

Query: 2325 ----PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
                PG PG  G  GP+G  G  G  GPPG  G+ G PG+PG  G  G +G
Sbjct: 908  GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 958



 Score =  261 bits (666), Expect = 1e-68
 Identities = 164/386 (42%), Positives = 197/386 (51%), Gaps = 40/386 (10%)

Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIG------------PKGIPGEDGYRGYPGDEG----- 2068
            EK   GVP    G  G +GP GS G             +G+ G+ G RG  G  G     
Sbjct: 833  EKGKLGVP-GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSR 891

Query: 2069 ---GP-GERGPPGVNGTQGFQGCPGQRGVKGSR---GFPGEKGEVGEIGLDGLDGEDGDK 2121
               GP G+ GP G +G  G  G PG+RG +G +   GFPG KG  G  G DGL G  G +
Sbjct: 892  GARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQR 951

Query: 2122 GLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE-----RGPKGETGDL 2176
            G  G  G+ G PG  G  GP+G  GE G +G RG PG PG   ++      G +G  GD 
Sbjct: 952  GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 1011

Query: 2177 GPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPA 2236
            GP G+ G+DG  G  G  G+ G  G +G PG KG +G  G PG  G  G RG+ G AGP 
Sbjct: 1012 GPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPI 1071

Query: 2237 GPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDD 2296
            G PG  G Q   GP G  G  GAPGE+G  GP GR G  G  G  G  G  G  GE GD 
Sbjct: 1072 GLPGRPGPQ---GPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1128

Query: 2297 GRDG-VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
            G  G  G +G +G KGE G PG PG +G  G PG+ G  G  G RG++G  G  G  G +
Sbjct: 1129 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1188

Query: 2356 GDPGYPGP------AGPKGNRGDSID 2375
            G PG PGP       GP G +G++ D
Sbjct: 1189 GFPGPPGPIGLQGLPGPPGEKGENGD 1214



 Score =  233 bits (595), Expect = 2e-60
 Identities = 144/350 (41%), Positives = 172/350 (49%), Gaps = 33/350 (9%)

Query: 2044 GPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK--------- 2094
            GP G  GP GI G  G +G  G  G PG+RGPPG  G  G  G PG  G           
Sbjct: 442  GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGG 501

Query: 2095 -GSRG--FPGEKGEVGEI---GLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER 2148
             GS+G     ++ +   I       L G  G  GL G  G  G PG  G KG  G+ G +
Sbjct: 502  DGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ 561

Query: 2149 GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208
            G  G++G PG          P G+ G  G  G  G  G+PG PG  G  G  G  G PG 
Sbjct: 562  GPRGVQGPPG----------PTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 611

Query: 2209 KGNKG--GP-GQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGR 2265
            KG++G  GP G PG  G+ G RG  G  GP G PG  G +G+ GPRG+ GA G PG  G 
Sbjct: 612  KGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV 671

Query: 2266 TGPLGRKGE---PGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPK 2322
             GP G KG     GEPGP G  GN GP+G  G  G   +G  G +G +G+ G  G PG  
Sbjct: 672  DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGP--IGPPGEKGPQGKPGLAGLPGAD 729

Query: 2323 GNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
            G PG PG  G +G KG  G  G  GP G  G +G  G  G  G KG++G+
Sbjct: 730  GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 779



 Score =  219 bits (559), Expect = 3e-56
 Identities = 142/353 (40%), Positives = 167/353 (47%), Gaps = 51/353 (14%)

Query: 2048 SIGPKGIPGEDGYRGYPGD-EGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEV 2106
            SI   G  GE G +G P   E G    GPPG  G  G  G PG +G  G  G PG++G  
Sbjct: 415  SINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPP 474

Query: 2107 GEIGLDGLDGEDGDKG----LPGSSGEKGNPGR--------------------RGDKGPR 2142
            G  GL G DG  G  G    LP   G  G+ G                     RG  GP 
Sbjct: 475  GRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPM 534

Query: 2143 GEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGR 2202
            G  G  G VG  G  G  G+ S + GP+G  G  GP   PG  G PG  G  G +GG G 
Sbjct: 535  GLTGRPGPVGGPGSSGAKGE-SGDPGPQGPRGVQGP---PGPTGKPGKRGRPGADGGRGM 590

Query: 2203 RGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE 2262
             G PGAKG++G  G PG  G++G RG +GP GP GPP                  G  G 
Sbjct: 591  PGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP------------------GDDGM 632

Query: 2263 RGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGP 2321
            RG  G +G +G PGE GP+G +G RG  G  G  G  GV G  G +G  G +G PG PG 
Sbjct: 633  RGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQ 692

Query: 2322 KGNPGEPGLNGTTGPKGIRGRRGNSGPPGIV---GQKGDPGYPGPAGPKGNRG 2371
            +GNPG  GL G  GP G  G +G  G PG+    G  G PG+PG  G  G +G
Sbjct: 693  QGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 745



 Score =  208 bits (530), Expect = 6e-53
 Identities = 117/275 (42%), Positives = 146/275 (53%), Gaps = 17/275 (6%)

Query: 2027 KACCGVPCKCSGQRGDRGPIGSIGP---KGIPGEDGYRGYPGDEGGPGERGPPG------ 2077
            +A  G P    G++G+ GP G+ GP   KG PG+DG +G PG  G PG+ GPPG      
Sbjct: 1268 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAG 1327

Query: 2078 ---VNGTQGFQGCPGQRGV---KGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKG 2131
               V G +G  G PGQ G     G  G PG  G+ G  G  G +G  G+KG  G +G +G
Sbjct: 1328 QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEG 1387

Query: 2132 NPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE--RGPKGETGDLGPMGVPGRDGVPG 2189
             PG+ G  GP+G  G+ G  G+RG PG  G+       G  G  G +GP G+PG  G PG
Sbjct: 1388 PPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPG 1447

Query: 2190 GPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISG 2249
              GE G  G  G  GPPG +G KG  G PG +G  G +G  G  GPAGP G  G  G+ G
Sbjct: 1448 SKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPG 1507

Query: 2250 PRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGI 2284
            P+G  G  G+ G  G+ G  G  G PG PGP G +
Sbjct: 1508 PQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1542



 Score =  186 bits (473), Expect = 2e-46
 Identities = 131/333 (39%), Positives = 155/333 (46%), Gaps = 26/333 (7%)

Query: 2057 EDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPG--EKGEVGEIGLDGL 2114
            ED     P +E GPG   P   + T+      G  G KG +G P   E G + E G  G 
Sbjct: 390  EDKPTSPPNEEFGPGV--PAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVE-GPPGP 446

Query: 2115 DGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNP-------GQDSQER 2167
             G  G  G PG  G  G PG  GD+GP G  G  G  G+ G PG         G D   +
Sbjct: 447  AGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGS-K 505

Query: 2168 GPKGETGDLGPMGV--PGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQG 2225
            GP     +     +    R  + G PG  G  G   R GP G  G+ G  G+ G  G QG
Sbjct: 506  GPTISAQEAQAQAILQQARIALRGPPGPMGLTG---RPGPVGGPGSSGAKGESGDPGPQG 562

Query: 2226 TRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERG---RTGPLGRKGEPGEPGPKG 2282
             RG QGP GP G PG  G  G  G RG  G  GA G+RG     G  G KG  GE GP+G
Sbjct: 563  PRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQG 622

Query: 2283 GIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGR 2342
              G  G  G  G+DG   +G  G  G+ G RG  G  G  G PG+PG+ G  GP G +G 
Sbjct: 623  PPGPPGDDGMRGEDGE--IGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGN 680

Query: 2343 RGNSGPPGIVGQKGDP---GYPGPAGPKGNRGD 2372
             G  G PG  GQ+G+P   G PGP GP G  G+
Sbjct: 681  MGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGE 713



 Score =  158 bits (399), Expect = 9e-38
 Identities = 100/240 (41%), Positives = 120/240 (50%), Gaps = 17/240 (7%)

Query: 2140 GPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGG 2199
            G  GEKG++G+  +  +PG         GP G  G  G MG PG  G  G PG+ G  G 
Sbjct: 420  GAYGEKGQKGEPAVV-EPG-----MLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGP 473

Query: 2200 FGRRGPPGAKGNKGGPGQ----PGFEGEQGTRGAQGPAGPAGPPGLIGEQGIS--GPRGS 2253
             GR G PGA G  G PG     P   G  G++G    A  A    ++ +  I+  GP G 
Sbjct: 474  PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGP 533

Query: 2254 GGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGER 2313
             G  G PG  G  G  G KGE G+PGP+G  G +GP G TG  G+      GR G  G R
Sbjct: 534  MGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGK-----RGRPGADGGR 588

Query: 2314 GFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373
            G PG PG KG+ G  GL G  G KG RG RG  GPPG  G  G  G  G  GP+G  G++
Sbjct: 589  GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 648


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score =  286 bits (733), Expect = 2e-76
 Identities = 159/344 (46%), Positives = 184/344 (53%), Gaps = 23/344 (6%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G  G  GPIGS GP+G PG+ G  G PG  G PGE          GF G PG RG  G+ 
Sbjct: 243  GDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGE---------VGFAGSPGARGFPGAP 293

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157
            G PG KG  G  GL+G  GE G  G  G +G  G  G  G  GPRG  GERG +G +G P
Sbjct: 294  GLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAP 353

Query: 2158 GNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQ 2217
            G  G      G  G+ G +GP+G+PG  G PG PG  G+ G  G RGP G +G +G  G 
Sbjct: 354  GQRGA----HGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGP 409

Query: 2218 PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGE 2277
            PG  G  G  GA G  G  G  G  G  G SGP GS G  G+PG +G TGP G +G+PG+
Sbjct: 410  PGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGD 469

Query: 2278 PGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGP---------KGNPGE 2327
            PG  G  G  GP+GE G  G  G +G  G  GK+G RG PG  GP          GN G 
Sbjct: 470  PGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGF 529

Query: 2328 PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
            PG +G  GPKG +G RG  G  G  G +GDPG PG  G  G RG
Sbjct: 530  PGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARG 573



 Score =  283 bits (725), Expect = 1e-75
 Identities = 161/369 (43%), Positives = 187/369 (50%), Gaps = 30/369 (8%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRG 2092
            P   +G  G  GP GS GP+GI G+ G  G PG +G  G +G PG +G QG  G PG+ G
Sbjct: 442  PPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEG 501

Query: 2093 VKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVG 2152
             +G RG PG  G  G +G  G  G  G  G  G  G KG  G RG  G  G KG +GD G
Sbjct: 502  KRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPG 561

Query: 2153 IRGDPGNPGQDSQERGP--KGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKG 2210
              G+PG PG       P  +G  G LGP+G PG DG PG PG  G  G  G  G PG KG
Sbjct: 562  RPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKG 621

Query: 2211 NKGGPGQPGFEGEQGTRGAQ---------GPAGPAGPPGLIGEQGISGPRGSGGAAGAPG 2261
            + G PG+PG  G  G  G +         GP+GP GPPGL GE+G  GP G  G  G PG
Sbjct: 622  SSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPG 681

Query: 2262 ERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGR----------------DGVGSEG 2305
              G  G  G+ G+ G PG  G +G  GPRGE G+ G                  G G +G
Sbjct: 682  PPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDG 741

Query: 2306 RRGKKGERGFPGYPGP---KGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPG 2362
             +G  G  G PG  GP   +G PGE G+ GT GPKG RG  G  G  G  G  G  G PG
Sbjct: 742  PKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPG 801

Query: 2363 PAGPKGNRG 2371
            P GP G  G
Sbjct: 802  PLGPPGPAG 810



 Score =  282 bits (722), Expect = 3e-75
 Identities = 164/370 (44%), Positives = 188/370 (50%), Gaps = 38/370 (10%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQG---CPGQRGVK 2094
            G +G+ GP G+ GP+G  G+ G  G PG  G PG  G  G +GT G +G    PG  G  
Sbjct: 384  GMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPP 443

Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGE---KGNPGRRGDKGPRGEKGERGDV 2151
            GS G PG  G  G  G  G+ G+ GD G+PG  GE   KG PG  G +GP G  GE G  
Sbjct: 444  GSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKR 503

Query: 2152 GIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGN 2211
            G RGDPG  G      GP GE G  G  G PG DG+PG  G  G+ G  G  GP G++G+
Sbjct: 504  GPRGDPGTVGPP----GPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGD 559

Query: 2212 KGGPGQPGFEGEQ---GTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2268
             G PG+PG  G +   G  G QGP G  GP G  GE G  GP GS G  G PG  G  GP
Sbjct: 560  PGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGP 619

Query: 2269 LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG----------VGSEGRRGKKGERGFPGY 2318
             G  G+PG+PG  G  G  G RG  G DG  G           G  G +G  G  GF G 
Sbjct: 620  KGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGL 679

Query: 2319 PGPKGNPGE------------PGLNGTTGPKGIRGRRGNSGPPGIV---GQKGDPGYPGP 2363
            PGP G PGE            PG  G  GP+G RG  G  G PGI    G+KG  G  GP
Sbjct: 680  PGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGP 739

Query: 2364 AGPKGNRGDS 2373
             GPKG+ G S
Sbjct: 740  DGPKGSPGPS 749



 Score =  282 bits (721), Expect = 4e-75
 Identities = 166/378 (43%), Positives = 193/378 (51%), Gaps = 31/378 (8%)

Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGT---Q 2082
            E+   G P    G +GDRG IG  G +G  G DG RG PG  G PG  GP G  G    +
Sbjct: 766  ERGIAGTP----GPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPR 821

Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGN---------- 2132
            G  G PG RG  GSRG  G  G VG  G  G DG+ G KG PG  G+KG+          
Sbjct: 822  GLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLA 881

Query: 2133 --PGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQ--ERGPKGETGDLGPMGVPGRDGVP 2188
              PG  G  G  G KG RG  G  G  G PG   +    GP G  G  GP+G PG++G P
Sbjct: 882  GSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPP 941

Query: 2189 GGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGIS 2248
            G  G+ G +G  G RGP G  G  G  G PG +G+ G  G  GPAG  G  G++G  G  
Sbjct: 942  GLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQR 1001

Query: 2249 GPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRR 2307
            G RG  G  G  G  G+ GP G  G+ G PGP G  G+ GP GE G +G  G  G+ GR 
Sbjct: 1002 GERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRD 1061

Query: 2308 GKKGERGFPGYPGPKGNPGEPGLNGTTGP---------KGIRGRRGNSGPPGIVGQKGDP 2358
            G  GERG  G PGP G PG  G  GT GP         +G  G RG  GPPG  G++G P
Sbjct: 1062 GAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLP 1121

Query: 2359 GYPGPAGPKGNRGDSIDQ 2376
            G  GP G KG+ GD  D+
Sbjct: 1122 GPQGPRGDKGDHGDRGDR 1139



 Score =  281 bits (720), Expect = 6e-75
 Identities = 162/360 (45%), Positives = 192/360 (53%), Gaps = 32/360 (8%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGD---EGGPGERGPPGVNGTQGFQGCPGQRG- 2092
            +G  G +GP G +GP G PGEDG  G PG     G PG  G PG  G+ G  G PG+ G 
Sbjct: 575  TGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGN 634

Query: 2093 --VKGSRGFPGEKGEVGE---IGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGE 2147
              V G RG PG+ GEVG    +G  GL GE G++G PG +G +G PG     GP GE G+
Sbjct: 635  AGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPG---PPGPPGEGGK 691

Query: 2148 RGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPG 2207
             GD G+ GDPG  G      GP+GE G+ G  G PG  G+PG  G  G +G  G +G PG
Sbjct: 692  PGDQGVPGDPGAVGP----LGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPG 747

Query: 2208 AKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTG 2267
              G  G  G PG +G  G RG  G  GP G  G IGE+G  G  G+ GA G PG  G  G
Sbjct: 748  PSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPG 807

Query: 2268 PLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG----------VGSEGRRGKKGERGFPG 2317
            P G  GE GEPGP+G +G  G RG  G  G +G           G +G+ G KGE G PG
Sbjct: 808  PAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPG 867

Query: 2318 Y------PGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
                   PGP+G  G PG +G  G  G++G RG  GPPG  G  G  G  GP GP G  G
Sbjct: 868  QKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPG 927



 Score =  277 bits (708), Expect = 1e-73
 Identities = 160/347 (46%), Positives = 183/347 (52%), Gaps = 18/347 (5%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPG------ERGPPGVNGTQGFQGCPGQ 2090
            SG  G  GP GS GP+G  G  G RG PGD G PG       +G PG +G QG  G PG+
Sbjct: 440  SGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGE 499

Query: 2091 RGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD 2150
             G +G RG PG  G  G +G  G  G  G  G  G  G KG  G RG  G  G KG +GD
Sbjct: 500  EGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGD 559

Query: 2151 VGIRGDPGNPGQDSQERGP--KGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208
             G  G+PG PG       P  +G  G LGP+G PG DG PG PG  G  G  G  G PG 
Sbjct: 560  PGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGP 619

Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2268
            KG+ G PG+PG  G  G  G +G       PG  GE G SGP G  G AG  GE+G  GP
Sbjct: 620  KGSSGDPGKPGEAGNAGVPGQRGA------PGKDGEVGPSGPVGPPGLAGERGEQGPPGP 673

Query: 2269 LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGE 2327
             G +G PG PGP G  G  G +G  GD G  G +G  G RG  GERG PG  G  G  G 
Sbjct: 674  TGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGM 733

Query: 2328 PGLNGTTGPKGI---RGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
             G +G  GPKG     G  G++GPPG+ G  G+ G  G  GPKG+RG
Sbjct: 734  AGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRG 780



 Score =  275 bits (704), Expect = 4e-73
 Identities = 158/359 (44%), Positives = 183/359 (50%), Gaps = 28/359 (7%)

Query: 2037 SGQRGDRGPIGSIGPK------GIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQ 2090
            +G  G+ G  GS G +      G+PG  G+RG+ G EG  GE G PG  G  G  G  G 
Sbjct: 272  NGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGA 331

Query: 2091 RGVKGSRGFPGEKGEV---------GEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGP 2141
             G  G RG PGE+G +         G  G+ G  G  G  G+PGSSG  GNPG +G+ GP
Sbjct: 332  MGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGP 391

Query: 2142 RGEKGERGDVGIRGDPGNPGQDSQER-----GPKGETGDLGPMGVPGRDGVPGGPGETGK 2196
             G +G  G  G RG+ G PG           G  G  G  GP G PG  G PG  G  G 
Sbjct: 392  TGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGS 451

Query: 2197 NGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGA 2256
             G  G  GP G +G  G PG PGF+GE G +G  GP G  GP G  GE+G  GPRG  G 
Sbjct: 452  PGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGT 511

Query: 2257 AGAPGERGRTGPLGRKGEPGE---PGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGER 2313
             G PG  G  G  G +G PG    PGPKG  G RGP G +G       GS+G  G+ GE 
Sbjct: 512  VGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPK-----GSQGDPGRPGEP 566

Query: 2314 GFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
            G PG  G  GNPG  G  G  GP G  G  G  GPPG +G +G PG  G  GPKG+ GD
Sbjct: 567  GLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGD 625



 Score =  275 bits (704), Expect = 4e-73
 Identities = 155/347 (44%), Positives = 179/347 (51%), Gaps = 8/347 (2%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRG 2092
            P    GQRG  G  G  GP G  G  G  G+PG+ G  GE GP G  G +G QG  G+ G
Sbjct: 349  PQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETG 408

Query: 2093 VKGSRGFPGEKGEVGEIGLDGLDGEDGDKGL---PGSSGEKGNPGRRGDKGPRGEKGERG 2149
              G  G PG  G +G  G  G  G  G  G    PGS+G  G+PG +G  GP+G +G+ G
Sbjct: 409  PPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPG 468

Query: 2150 DVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAK 2209
            D G+ G  G  G    E GP G  G +GP G  G+ G  G PG  G  G  G RG PG +
Sbjct: 469  DPGVPGFKGEAGPKG-EPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNR 527

Query: 2210 GNKGGPGQPGFEGEQGTR---GAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRT 2266
            G  G  G PG +G QG R   G+ GP G  G PG  GE G+ G RG  G  G  G  G+ 
Sbjct: 528  GFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKL 587

Query: 2267 GPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNP 2325
            GPLG  GE G PGP G IG RG  G  G  G  G  G  G+ G+ G  G PG  G  G  
Sbjct: 588  GPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKD 647

Query: 2326 GEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
            GE G +G  GP G+ G RG  GPPG  G +G PG PGP G  G  GD
Sbjct: 648  GEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGD 694



 Score =  272 bits (695), Expect = 4e-72
 Identities = 163/380 (42%), Positives = 190/380 (50%), Gaps = 36/380 (9%)

Query: 2033 PCKCSGQRGDRGPIGSIGPK------------GIPGEDGYRGYPGDEGGPGERGPPGVN- 2079
            P    G  G+RG  G+ GPK            G  G DG RG PG  G PG  GP G   
Sbjct: 757  PPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKG 816

Query: 2080 --GTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEK------- 2130
              G +G  G PG RG  GSRG  G  G VG  G  G DG+ G KG PG  G+K       
Sbjct: 817  EPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPG 876

Query: 2131 -----GNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQ--ERGPKGETGDLGPMGVPG 2183
                 G+PG  G  G  G KG RG  G  G  G PG   +    GP G  G  GP+G PG
Sbjct: 877  PQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPG 936

Query: 2184 RDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIG 2243
            ++G PG  G+ G +G  G RGP G  G  G  G PG +G+ G  G  GPAG  G  G++G
Sbjct: 937  KEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVG 996

Query: 2244 EQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VG 2302
              G  G RG  G  G  G  G+ GP G  G+ G PGP G  G+ GP GE G +G  G  G
Sbjct: 997  MPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDG 1056

Query: 2303 SEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGI------RGRRGNSGPPGIVGQKG 2356
            + GR G  GERG  G PGP G PG  G  GT GP G       RG  G+ GP G  G+ G
Sbjct: 1057 TPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAG 1116

Query: 2357 DPGYPGPAGPKGNRGDSIDQ 2376
              G PGP GP+G++GD  D+
Sbjct: 1117 KRGLPGPQGPRGDKGDHGDR 1136



 Score =  265 bits (677), Expect = 5e-70
 Identities = 156/353 (44%), Positives = 187/353 (52%), Gaps = 17/353 (4%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRG---YPGDEGGPGERGPPGVNGTQGFQGCPG 2089
            P    G  G +GP G  G KG PGE G +G    PG +G  G  GP G NG  G +G  G
Sbjct: 841  PTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRG 900

Query: 2090 QRGVKGSRGFPGEKGEVGEIGLDGLDG------EDGDKGLPGSSGEKGNPGRRGDKGPRG 2143
             +G  G+ GFPG  G VG  G  G  G      E G +G PG  G+ G+ GR GD+GP G
Sbjct: 901  TQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAG 960

Query: 2144 EKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRR 2203
              G  GD G  G+ G PG D    GP G TG  G +G+PG+ G  G PG  G  G  G+ 
Sbjct: 961  PPGGPGDKGDPGEDGQPGPDGPP-GPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKV 1019

Query: 2204 GPPGAKGNKGGPGQ---PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAP 2260
            GP GA G+KG PG    PG  G  G  G +GPAG  G PG  G  G  G RG  G AG P
Sbjct: 1020 GPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLP 1079

Query: 2261 GERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYP 2319
            G +G  G  G  G PG+ G +G  G+RGP G  G  G+ G+ G +G RG KG+ G  G  
Sbjct: 1080 GSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDR 1139

Query: 2320 GPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
            G KG+ G  GL G  GP G  G +G++G PG  G +G PG   P GP G  G+
Sbjct: 1140 GQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPG---PVGPSGKEGN 1189



 Score =  263 bits (673), Expect = 2e-69
 Identities = 156/364 (42%), Positives = 179/364 (49%), Gaps = 33/364 (9%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            GQ+GD G  G  G  G PG  G  G PG +GG G +GPPG  G   F G  G+ G  G  
Sbjct: 867  GQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATG---FPGSAGRVGPPGPA 923

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGL------------PGSSGEKGNPGRRGDKGPRGEK 2145
            G PG  G +GE G +G  G  GD G             PG  G+KG+PG  G  GP G  
Sbjct: 924  GAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPP 983

Query: 2146 GERGDVGIRGDPGNPGQDSQER-----GPKGETGDLGPMGVPGRDGVPGGPGETGKNGGF 2200
            G  G  G RG  G PGQ  +       GP G  G +GP G  G  G PG  G  G NG  
Sbjct: 984  GPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPV 1043

Query: 2201 GRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAP 2260
            G  GP G  GN G PG+ G  GE+G RG  GPAG  G  G  G  G  G  G  G  G P
Sbjct: 1044 GEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDP 1103

Query: 2261 GERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-------VGSEGRRGKKGER 2313
            G RG  GP GR G+ G PGP+G  G++G  G+ GD G+ G        G  G  G  GE+
Sbjct: 1104 GSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQ 1163

Query: 2314 GFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGI------VGQKGDPGYPGPAGPK 2367
            G  G PGP G  G PG  G +G +G  G  G  GPPG+       G +G PG PGP GP 
Sbjct: 1164 GSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPP 1223

Query: 2368 GNRG 2371
            G  G
Sbjct: 1224 GPPG 1227



 Score =  262 bits (669), Expect = 5e-69
 Identities = 156/363 (42%), Positives = 188/363 (51%), Gaps = 31/363 (8%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            GQ+G+ G +  +   GI G  G  G PG +G  GERGP G  G +G QG  G+ GV G  
Sbjct: 113  GQKGEPGLVPVV--TGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQP 170

Query: 2098 GFPGEKGEVGEIGLDGLD--------GEDGDKGLPGSSG-EKGNPGRRGDKGPRGEKGER 2148
            G PG  G     G DGL         G D   GL    G   G+ G  G +GP+G +G++
Sbjct: 171  GAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQ 230

Query: 2149 GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208
            G  G  G PG PG    + GP G  G  GP G PG+ G  G PG  G  G  G  G PGA
Sbjct: 231  GGAGPTGPPGEPG----DPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGA 286

Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSG---GAAGAPGERGR 2265
            +G  G PG PG +G +G +G +GP G  G PG  GE G +GP G+    G  G PGERGR
Sbjct: 287  RGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGR 346

Query: 2266 TGPLGRKGE------PGEPGPKGGIGNRGPRGETGDDGRDG----VGSEGRRGKKGERGF 2315
             GP G  G+      PG+PGP G +G  G  G  G+ G  G     G+ G  G +G+RG 
Sbjct: 347  LGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGE 406

Query: 2316 PGYPGPKGNPGEP---GLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
             G PGP G+PG P   G +GT G KG  G  G SGPPG  G  G PG  G  GP+G RG 
Sbjct: 407  TGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQ 466

Query: 2373 SID 2375
              D
Sbjct: 467  PGD 469



 Score =  208 bits (529), Expect = 8e-53
 Identities = 119/284 (41%), Positives = 144/284 (50%), Gaps = 35/284 (12%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGT---QGFQGCPGQRGVK 2094
            G  G  G +G  GP G PG  G +G PG++G PG  GPPG  GT   +G  G PGQRG +
Sbjct: 945  GDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGER 1004

Query: 2095 GSRGFPG---------------EKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDK 2139
            G  G PG               +KG  G +G  G +G  G+ G  G +G  G PGR G  
Sbjct: 1005 GMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAV 1064

Query: 2140 GPRGEKGERGDVGIRGDPGNPGQ--------DSQERGPKGETGDLGPMGVPGRDGVPGGP 2191
            G RG++G+ G  G+ G  G PG         D+ +RG  G  G +GP G  G+ G+PG  
Sbjct: 1065 GERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQ 1124

Query: 2192 GETGKNGGFGRRGPPGAKGNKGG------PGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQ 2245
            G  G  G  G RG  G KG++G       PG PG  GEQG+ G  GP GP GPPG +G  
Sbjct: 1125 GPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPS 1184

Query: 2246 GISGPRGSGGAAGAPGERG---RTGPLGRKGEPGEPGPKGGIGN 2286
            G  G  G  G  G PG RG     GP G  GEPG PGP G  G+
Sbjct: 1185 GKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGH 1228



 Score =  169 bits (429), Expect = 3e-41
 Identities = 107/268 (39%), Positives = 125/268 (46%), Gaps = 53/268 (19%)

Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGT---- 2081
            ++   G+P    GQRG+RG  G  GP G PG+ G  G  GD+G PG  GPPG NG     
Sbjct: 991  QRGIVGMP----GQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEP 1046

Query: 2082 -----QGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRR 2136
                  G  G PG+ G  G RG  G+ G  G  G  G  G  G  G PG +G++G+PG R
Sbjct: 1047 GPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSR 1106

Query: 2137 GD---------------KGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGV 2181
            G                +GPRG+KG+ GD   RGD          RG KG  G  G  G+
Sbjct: 1107 GPIGPPGRAGKRGLPGPQGPRGDKGDHGD---RGD----------RGQKGHRGFTGLQGL 1153

Query: 2182 PGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGL 2241
            PG  G  G  G  G  G FG RGPPG  G  G  G P            GP GP GPPG+
Sbjct: 1154 PGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNP------------GPLGPIGPPGV 1201

Query: 2242 IGEQGISGPRGSGGAAGAPGERGRTGPL 2269
             G  G +GP G  G  G PG  G  G L
Sbjct: 1202 RGSVGEAGPEGPPGEPGPPGPPGPPGHL 1229



 Score =  165 bits (418), Expect = 6e-40
 Identities = 108/261 (41%), Positives = 120/261 (45%), Gaps = 40/261 (15%)

Query: 2124 PGSSGEKGNPGRRGDKGPRG----EKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPM 2179
            PG        GR+G KG  G      G RG  G  G PG+ G    ERGPKG  G  GP 
Sbjct: 100  PGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRG-ERGPKGRPGPRGPQ 158

Query: 2180 GVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGP-----AG 2234
            G+   DG PG PG+                   G PG PG     G  G   P     AG
Sbjct: 159  GI---DGEPGVPGQ------------------PGAPGPPGHPSHPGPDGLSRPFSAQMAG 197

Query: 2235 PAGPPGLIGEQGIS----GPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPR 2290
                 GL  + G+     GP G  G  G  G++G  GP G  GEPG+PGP G IG+RGP 
Sbjct: 198  LDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPE 257

Query: 2291 GETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPG 2350
            G  G  G D  G  GR G  GE GF G PG +G PG PGL G    KG RG +G  GP G
Sbjct: 258  GPPGKPGED--GEPGRNGNPGEVGFAGSPGARGFPGAPGLPGL---KGHRGHKGLEGPKG 312

Query: 2351 IVGQKGDPGYPGPAGPKGNRG 2371
             VG  G  G  GP GP G  G
Sbjct: 313  EVGAPGSKGEAGPTGPMGAMG 333



 Score = 62.8 bits (151), Expect = 5e-09
 Identities = 46/122 (37%), Positives = 57/122 (46%), Gaps = 19/122 (15%)

Query: 2275 PGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGE-------RGFPGYPGPKGNPGE 2327
            PGE  P   + ++ P G   + GR      GR+G+KGE        G  G PGP G PG 
Sbjct: 89   PGECCP---VCSQTPGGGNTNFGR------GRKGQKGEPGLVPVVTGIRGRPGPAGPPGS 139

Query: 2328 PGLNGTTGPKGI---RGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIK 2384
             G  G  GPKG    RG +G  G PG+ GQ G PG PG     G  G S    A +  + 
Sbjct: 140  QGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLD 199

Query: 2385 DK 2386
            +K
Sbjct: 200  EK 201


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  286 bits (732), Expect = 2e-76
 Identities = 161/346 (46%), Positives = 181/346 (52%), Gaps = 12/346 (3%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGC---PGQRGVK 2094
            G  G+ G  G  GPKG  G  G  G  GD G PGERGPPG+ G  G +G    PG  G K
Sbjct: 648  GPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGK 707

Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154
            G+ G PG  G  G  GL G+ GE G  G PG  G+KG PG  G  G  G+ G RG  G  
Sbjct: 708  GAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPI 767

Query: 2155 GDPGNPGQ--DSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNK 2212
            G PG  GQ  D  E G  G  G  GP G PG  G  G PG  G  G  G+ G PG KG +
Sbjct: 768  GPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGER 827

Query: 2213 GGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRK 2272
            G PG+ G  G  G  G  G +GPAGPPG  G +G  G  G  GAAG PG RG  GP G  
Sbjct: 828  GAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSN 887

Query: 2273 GEPGEPGPKGGIGNRGPRGETGDDGRDG----VGSEGRRGKKGERGFPGYPGPKGNPGEP 2328
            G PG PGP G  G  GP G  G+ G  G     G +G  G+ GE+G PG  GP G PG  
Sbjct: 888  GNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPL 947

Query: 2329 GLNGTTGPKGIRGRRGNSGP---PGIVGQKGDPGYPGPAGPKGNRG 2371
            G+ G TG +G+ G  G  GP   PG  G KG+ G PG  G  G RG
Sbjct: 948  GIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERG 993



 Score =  284 bits (727), Expect = 9e-76
 Identities = 165/361 (45%), Positives = 188/361 (52%), Gaps = 19/361 (5%)

Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQ 2085
            E    G+P   +G+RG  G  G  GP GIPGE   +G  G+ G PG  GP G  G  G  
Sbjct: 472  EPGANGLP-GAAGERGAPGFRGPAGPNGIPGE---KGPAGERGAPGPAGPRGAAGEPGRD 527

Query: 2086 GCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEK 2145
            G PG  G++G  G PG  G  G+ G  G  GE G  G PG SG +G PG  G  GP+G  
Sbjct: 528  GVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGND 587

Query: 2146 GERGDVGIRGDPGNPGQDSQ-----ERGPKGETGDLGP------MGVPGRDGVPGGPGET 2194
            G  G  G RG PG PG         E GP+G  G  GP       G PG  G+ G PG  
Sbjct: 588  GAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTG 647

Query: 2195 GKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSG 2254
            G  G  G+ G PG KG+ G PG PG +G+ G  G +GP G AG PGL G  G  GP G  
Sbjct: 648  GPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGK 707

Query: 2255 GAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGER 2313
            GAAG PG  G  G  G +G PGE G  G  G +G +GE G  G DGV G +G RG  G  
Sbjct: 708  GAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPI 767

Query: 2314 GFP---GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNR 2370
            G P   G PG KG  G PGL G  GP+G  G RG +GPPG  G  G PG  G  G KG R
Sbjct: 768  GPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGER 827

Query: 2371 G 2371
            G
Sbjct: 828  G 828



 Score =  280 bits (716), Expect = 2e-74
 Identities = 165/364 (45%), Positives = 191/364 (52%), Gaps = 31/364 (8%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGV---- 2093
            G  G RG  G  G  G+PG  G RG  G  G  G+ GPPG  GT GF G PG +G     
Sbjct: 297  GPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPA 356

Query: 2094 --KGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGN---------PGRRGDKGPR 2142
               GS G PG++GE G  G  G  G  G  G+ GS G KG          PG  G +GP 
Sbjct: 357  GSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPP 416

Query: 2143 GEKGERGDVGIRGDPGNPGQDSQ--ERGPKGETGDLGPMGVPG------RDGVPGGPGET 2194
            G  G  G  G+RG  G PG++    E GP+GE G+ G  GVPG      +DG PG PG  
Sbjct: 417  GPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGAN 476

Query: 2195 GKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGP---AGPPGLIGEQGISGPR 2251
            G  G  G RG PG +G  G  G PG +G  G RGA GPAGP   AG PG  G  G  G R
Sbjct: 477  GLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMR 536

Query: 2252 GSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKG 2311
            G  G+ G PG  G+ GP G +GE G PGP G  G RG  G  G  G    G++G  GK G
Sbjct: 537  GMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPK--GNDGAPGKNG 594

Query: 2312 ERGFPGYPGPKGNP---GEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKG 2368
            ERG PG PGP+G P   GE G  G  GP G  G +G++GPPG  G +G PG  GP G  G
Sbjct: 595  ERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENG 654

Query: 2369 NRGD 2372
              G+
Sbjct: 655  KPGE 658



 Score =  279 bits (714), Expect = 3e-74
 Identities = 160/375 (42%), Positives = 187/375 (49%), Gaps = 47/375 (12%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096
            +G  G  GP G+IGP G  G+DG  G PG  G  G  GPPG+ G  G  G PG +G +G 
Sbjct: 209  AGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGF 268

Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGD 2156
             G  GEKGE G  GL G +G  G+ G PG  G +G PG RG  G  G  G RG+ G RG 
Sbjct: 269  DGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGS 328

Query: 2157 PGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPG 2216
             G PG       P G  G  G  G PG  G  G  G  G NG  G+RG PG +G+ G  G
Sbjct: 329  DGQPG-------PPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQG 381

Query: 2217 QPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPG 2276
             PG  G  G+ G +G  GPAG PG  G  G  GP G  GA GAPG RG  G  G+ G  G
Sbjct: 382  PPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKG 441

Query: 2277 EPGPKGGIGNR---GPRGETGDDGRDGV----------------------------GSEG 2305
            EPGP+G  G     G  G  G+DG+DG                             G  G
Sbjct: 442  EPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPG 501

Query: 2306 RRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGN---------SGPPGIVGQKG 2356
             +G  GERG PG  GP+G  GEPG +G  G  G+RG  G+          GPPG  G+ G
Sbjct: 502  EKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESG 561

Query: 2357 DPGYPGPAGPKGNRG 2371
             PG PGP+GP+G  G
Sbjct: 562  RPGPPGPSGPRGQPG 576



 Score =  279 bits (714), Expect = 3e-74
 Identities = 165/359 (45%), Positives = 182/359 (50%), Gaps = 30/359 (8%)

Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPG------DEGGPGERGPPGVNGTQGF 2084
            GVP K  G RG  GPIG  GP G PG+ G  G PG        G PGERG  G  G  GF
Sbjct: 753  GVPGK-DGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGF 811

Query: 2085 QGCPGQRGV---KGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGP 2141
             G PGQ G    KG RG PGEKGE G  G+          G PG SG  G PG +G KG 
Sbjct: 812  PGAPGQNGEPGGKGERGAPGEKGEGGPPGV---------AGPPGGSGPAGPPGPQGVKGE 862

Query: 2142 RGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFG 2201
            RG  G  G  G  G  G PG      G  G  G  GP G PG+DG PG  G TG  G  G
Sbjct: 863  RGSPGGPGAAGFPGARGLPGPP----GSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPG 918

Query: 2202 RRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPG 2261
              GP G  G  G  G PG +G  G  G  G AG  G  GL G  G+ GPRGS G  G  G
Sbjct: 919  VSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKG 978

Query: 2262 ERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-------GSEGRRGKKGERG 2314
            E G+ G  G  GE G PGP+G  G  G  GE G DG  G        GS G +G +GE G
Sbjct: 979  ESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENG 1038

Query: 2315 FPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373
             PG PG  G+PG PG  G  G  G RG  G +GP G  G  G  G PGP GP+G++G++
Sbjct: 1039 SPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGET 1097



 Score =  278 bits (711), Expect = 6e-74
 Identities = 161/379 (42%), Positives = 190/379 (50%), Gaps = 49/379 (12%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERG---PPGVNGTQGFQGC---PGQR 2091
            G+RG+ GP G  G  G PG++G  G  G+ G PGE+G   PPGV G  G  G    PG +
Sbjct: 798  GERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQ 857

Query: 2092 GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDV 2151
            GVKG RG PG  G  G  G  GL G  G  G PG  G  G+PG+ G  GP G  G  G  
Sbjct: 858  GVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSP 917

Query: 2152 GIRGDPGNPGQDSQE-----RGPKGETGDLG------------------PMGVPGRDGVP 2188
            G+ G  G+ GQ  ++     +GP G  G LG                  P G PG  GV 
Sbjct: 918  GVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVK 977

Query: 2189 GGPGETGKNGGFGRRGPPGAKG------------NKGGPGQPGFEGEQGTRGAQGPAGPA 2236
            G  G+ G NG  G RGPPG +G              G PG  G  G  G+ G +G  G  
Sbjct: 978  GESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGEN 1037

Query: 2237 GPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDD 2296
            G PG  G  G  GP G  G AG  G+RG +GP G  G PG  G +G  G +GPRG+ G+ 
Sbjct: 1038 GSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGE- 1096

Query: 2297 GRDGVGSEGRRGKKGERGFPGYPGPKGNP---GEPGLNGTTGPKGIRGRRGNSGPPGIVG 2353
                 G  G  G KG RGFPG PG  G+P   G+ G  G+ GP G RG  G SGPPG  G
Sbjct: 1097 ----TGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDG 1152

Query: 2354 QKGDPGYPGPAGPKGNRGD 2372
              G PG  GP GP+GNRG+
Sbjct: 1153 TSGHPGPIGPPGPRGNRGE 1171



 Score =  271 bits (692), Expect = 1e-71
 Identities = 159/396 (40%), Positives = 190/396 (47%), Gaps = 57/396 (14%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G +GD+G  G  G  G+PG+DG RG  G  G PG  G PG    +G  G PG  G+ G R
Sbjct: 738  GPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPG---DKGEGGAPGLPGIAGPR 794

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157
            G PGE+GE G  G  G  G  G  G PG  GE+G PG +G+ GP G  G  G  G  G P
Sbjct: 795  GSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPP 854

Query: 2158 GNPGQDSQERGP--KGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGP 2215
            G  G   +   P   G  G  G  G+PG  G  G PG  G +G  G+ GPPG  GN G P
Sbjct: 855  GPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAP 914

Query: 2216 GQPGFEG------EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPL 2269
            G PG  G      + G +G+ G  GP G PG +G  GI+G RG  G  G PG RG  GP 
Sbjct: 915  GSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQ 974

Query: 2270 GRKGEPGEPGPKGGIGNRGP---------RGETGDDGRDGV----------GSEGRRGKK 2310
            G KGE G+PG  G  G RGP          G  G+ GRDG           GS G +G +
Sbjct: 975  GVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDR 1034

Query: 2311 GERGFPGYPGPKGNPGEPG---------------------------LNGTTGPKGIRGRR 2343
            GE G PG PG  G+PG PG                             G  GP+G RG +
Sbjct: 1035 GENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDK 1094

Query: 2344 GNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCAL 2379
            G +G  G  G KG  G+PG  G  G+ G +  Q A+
Sbjct: 1095 GETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAI 1130



 Score =  269 bits (688), Expect = 3e-71
 Identities = 164/385 (42%), Positives = 191/385 (49%), Gaps = 57/385 (14%)

Query: 2038 GQRGDRGPIGSIGPKGIPG---EDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094
            GQ G  GP G+ G  G PG   E G  G PG  G PG+RG PG  G  G QG PG  G+ 
Sbjct: 330  GQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGIN 389

Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRG------------DKGPR 2142
            GS   PG KGE+G  G+ G  G  G +G PG +G  G PG RG            + GPR
Sbjct: 390  GS---PGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPR 446

Query: 2143 GEKGE---------RGDVGIRGDPGNPGQD-----SQERGPKGETGDLGPMGVPGRD--- 2185
            GE+GE         +G+ G  G PG PG +     + ERG  G  G  GP G+PG     
Sbjct: 447  GERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPA 506

Query: 2186 ------------GVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPA 2233
                        G  G PG  G  GG G RG PG+ G  G  G+PG  G QG  G  GP 
Sbjct: 507  GERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPP 566

Query: 2234 GPAGPPGLIGEQGISGPRGSGGAAGAPGER------GRTGPLGRKGEPGEPGPKGGIGNR 2287
            GP+GP G  G  G  GP+G+ GA G  GER      G  GP G+ GE G  GP G  G  
Sbjct: 567  GPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPG 626

Query: 2288 GPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNS 2346
            G +G+TG  G  G+ G  G  G  GE G PG PGPKG+ G P   G  G KG  G  G  
Sbjct: 627  GDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAP---GAPGGKGDAGAPGER 683

Query: 2347 GPPGIVGQKGDPGYPGPAGPKGNRG 2371
            GPPG+ G  G  G  GP GP+G +G
Sbjct: 684  GPPGLAGAPGLRGGAGPPGPEGGKG 708



 Score =  268 bits (686), Expect = 5e-71
 Identities = 170/415 (40%), Positives = 202/415 (48%), Gaps = 77/415 (18%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEG--GP----------GERGPPG---VNGTQ 2082
            GQRG+ GP G  G +G PG  G  G PG +G  GP          G RGPPG    NG  
Sbjct: 366  GQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAP 425

Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVGEIGL------------DGLDGEDGDKGLPGSSGEK 2130
            G +G  G+ G  G++G PG +GE GE G+            DG  GE G  GLPG++GE+
Sbjct: 426  GLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGER 485

Query: 2131 GNPGRRG---------DKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGV 2181
            G PG RG         +KGP GE+G  G  G RG  G PG+D    GP G  G  G  G 
Sbjct: 486  GAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGP-GMRGMPGSPGG 544

Query: 2182 PGRDGVPGGPGETGKNG-----------------GF----GRRGPPGAKGNKGGPGQPGF 2220
            PG DG PG PG  G++G                 GF    G  G PG  G +GGPG PG 
Sbjct: 545  PGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGP 604

Query: 2221 EGEQGTRGAQGPAGPAGPPGLIGEQGISGP------RGSGGAAGAPGERGRTGPLGRKGE 2274
            +G  G  G  GP GP GP G  G++G +GP      +G  G  G PGE G+ G  G KG+
Sbjct: 605  QGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGD 664

Query: 2275 PGEPGPKGGIGNRGPRGETGDDG-------RDGVGSEGRRGKKGERGFPGYPGP------ 2321
             G PG  GG G+ G  GE G  G       R G G  G  G KG  G PG PG       
Sbjct: 665  AGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGL 724

Query: 2322 KGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQ 2376
            +G PGE G  G+ GPKG +G  G  G  G+ G+ G  G  GP GP G  G   D+
Sbjct: 725  QGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDK 779



 Score =  266 bits (680), Expect = 2e-70
 Identities = 159/363 (43%), Positives = 183/363 (50%), Gaps = 35/363 (9%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G  G  GP G  GP G PG  G+ G PG  G  G  G PG  G  G  G PG  G  G  
Sbjct: 168  GLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPA 227

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157
            G  GE G  G  G  GL G  G KG  G  G  G  G RG  G  GEKGE G  G++G+ 
Sbjct: 228  GKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGEN 287

Query: 2158 GNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQ 2217
            G PG++       G  G +GP G PG  G PG PG  G  G  G RG  G  G  G PG 
Sbjct: 288  GLPGEN-------GAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGT 340

Query: 2218 PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAA---------GAPGERGRTGP 2268
             GF G  G +G  GPAG  G  G  G++G  GP+G  GA          G+PG +G  GP
Sbjct: 341  AGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGP 400

Query: 2269 LGRKGEP------GEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGP 2321
             G  G P      G PGP G  G  G RG  G+ G++G  G  G RG++GE G PG PG 
Sbjct: 401  AGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGA 460

Query: 2322 K------GNPGEPGLNGTTGPKGIRGR---RGNSGPPGIVGQK---GDPGYPGPAGPKGN 2369
            K      G+PGEPG NG  G  G RG    RG +GP GI G+K   G+ G PGPAGP+G 
Sbjct: 461  KGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGA 520

Query: 2370 RGD 2372
             G+
Sbjct: 521  AGE 523



 Score =  191 bits (484), Expect = 1e-47
 Identities = 118/283 (41%), Positives = 139/283 (49%), Gaps = 41/283 (14%)

Query: 2130 KGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDS------------QERGPKGETGDL- 2176
            +G  G +GD GP G  G  GD GI G PG+PG               Q   P+ ++ D+ 
Sbjct: 102  QGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVK 161

Query: 2177 ------GPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQ 2230
                  G  G PG  G PG PG  G +G  G  G PG +G  G PGQ G  G  G  GA 
Sbjct: 162  SGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAI 221

Query: 2231 GPAGPAGP------PGLIGEQGISGPRGSGGAAGAPG---------------ERGRTGPL 2269
            GP+GPAG       PG  GE+G+ GP G  G AG PG               E+G TG  
Sbjct: 222  GPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAP 281

Query: 2270 GRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEP 2328
            G KGE G PG  G  G  GPRG  G+ GR G+ G+ G RG  G RG  G PGP G PG  
Sbjct: 282  GLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTA 341

Query: 2329 GLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
            G  G+ G KG  G  G+ G  G  GQ+G+PG  G AG +G  G
Sbjct: 342  GFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPG 384



 Score =  169 bits (429), Expect = 3e-41
 Identities = 108/280 (38%), Positives = 128/280 (45%), Gaps = 54/280 (19%)

Query: 2038 GQRGDRGPIGSIGPKGI------------PGEDGYRGYPGDEGGPGERGPPGVNGTQGFQ 2085
            G  G +GP G+ GP GI            PG  G RG PG +G  GE G PG NG  G +
Sbjct: 933  GSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGER 992

Query: 2086 GCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDG---------DKGLPGSSGEKGNPGRR 2136
            G PG +G+ G  G  GE G  G  G DGL G DG         + G PG+ G  G+PG  
Sbjct: 993  GPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPP 1052

Query: 2137 GDKGPRGEKGERGDVGIRGDPGNPGQDSQE--------RGPKGETGDLGPMGV------P 2182
            G  GP G+ G+RG+ G  G  G PG             RG KGETG+ G  G+      P
Sbjct: 1053 GPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFP 1112

Query: 2183 GRDGVPGGPGETGKNGGFGR------------RGPPGAKGNKGGPGQ---PGFEGEQGTR 2227
            G  G PG PG  G+ G  G              GPPG  G  G PG    PG  G +G R
Sbjct: 1113 GNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGER 1172

Query: 2228 GAQGPAGPAGPPGLIGEQGISGP----RGSGGAAGAPGER 2263
            G++G  G  G PG  G  G  GP     G+   AG  GE+
Sbjct: 1173 GSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEK 1212



 Score =  144 bits (364), Expect = 1e-33
 Identities = 93/245 (37%), Positives = 100/245 (40%), Gaps = 42/245 (17%)

Query: 2169 PKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQ---- 2224
            P GE   + P         P G G  G  G  G  G PG  G+ G PGQPG  G      
Sbjct: 80   PFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPG 139

Query: 2225 ----------------------------GTRGAQGPAGPAGPPGLIGEQGISGPRGSGGA 2256
                                        G  G  GPAGP GPPG  G  G  G  GS G 
Sbjct: 140  ICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGY 199

Query: 2257 AGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV----------GSEGR 2306
             G PGE G+ GP G  G PG  GP G  G  G  G  G  G  G+          G  G 
Sbjct: 200  QGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGF 259

Query: 2307 RGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGP 2366
             G KG RGF G  G KG  G PGL G  G  G  G  G  GP G  G++G PG PG AG 
Sbjct: 260  PGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGA 319

Query: 2367 KGNRG 2371
            +GN G
Sbjct: 320  RGNDG 324



 Score =  120 bits (302), Expect = 2e-26
 Identities = 77/175 (44%), Positives = 89/175 (50%), Gaps = 19/175 (10%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPG------DEGGPGERGPPGVNGTQGFQG 2086
            P   +G+ GDRG  G  GP G PG  G RG PG      D+G  GERG  G+ G +GF  
Sbjct: 1054 PVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGF-- 1111

Query: 2087 CPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKG 2146
             PG  G  GS G  G++G +G  G  G  G  G  G PG  G  G+PG  G  GPRG +G
Sbjct: 1112 -PGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRG 1170

Query: 2147 ERGDVGIRGDPGNPGQDSQERGPKGETGDLGP-MGVPGRDGVPGGPGETGKNGGF 2200
            ERG     G PG+PGQ     GP G  G  GP  G  G   + G  GE  K GGF
Sbjct: 1171 ERGS---EGSPGHPGQP----GPPGPPGAPGPCCGGVGAAAIAGIGGE--KAGGF 1216



 Score = 84.7 bits (208), Expect = 1e-15
 Identities = 61/163 (37%), Positives = 71/163 (43%), Gaps = 27/163 (16%)

Query: 2232 PAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP---LGRKGEPGEPGPKGGIGNRG 2288
            P  P G    +  Q  + P       G  G +G  GP    GR G+PG PG  G  G+ G
Sbjct: 77   PEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPG 136

Query: 2289 PRG-----ETGD----------DGRDGVGSEGRRGKKGERGFPGYPGP---KGNPGEPGL 2330
            P G      TG           D + GV   G  G  G  G PG PGP    G+PG PG 
Sbjct: 137  PPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGS 196

Query: 2331 NGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373
             G  GP G  G+ G SGPP      G PG  GP+GP G  G+S
Sbjct: 197  PGYQGPPGEPGQAGPSGPP------GPPGAIGPSGPAGKDGES 233


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score =  285 bits (729), Expect = 5e-76
 Identities = 163/351 (46%), Positives = 187/351 (53%), Gaps = 17/351 (4%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGV------NGTQGFQGCPGQR 2091
            G +GD+G  G  G  GI G  G+ G PG +G  G RGPPG+      +G +GF G  G  
Sbjct: 1088 GSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPP 1147

Query: 2092 GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRG---DKGPRGEKGER 2148
            G++G  G PGEKGEVG++G  G  G  G +G  G +G +G PG  G     G  GEKGER
Sbjct: 1148 GLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGER 1207

Query: 2149 GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208
            GD G  G PG PG     +G  GE GD GP G  G  G  G PGE G  G  G  G PG 
Sbjct: 1208 GDAGDPGPPGAPGIPGP-KGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGD 1266

Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2268
             G  G PG  G +G  G +G  G  G  GPPG  GE G  GP G  G +G  G  GR G 
Sbjct: 1267 LGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGE 1326

Query: 2269 LGRKGEPGEPGPKGG---IGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGN 2324
             G KGEPG  GP G    +G RGP G  G +G  G+ G  G  G  G  G  G PGP G 
Sbjct: 1327 KGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGP 1386

Query: 2325 PGEPGLNGTTGPKGIRGRRGNSG---PPGIVGQKGDPGYPGPAGPKGNRGD 2372
             G PGL G TGPKG +G  G  G   PPG  G+KGD G PG  GP G +GD
Sbjct: 1387 SGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGD 1437



 Score =  284 bits (726), Expect = 1e-75
 Identities = 169/410 (41%), Positives = 202/410 (49%), Gaps = 52/410 (12%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G  G++GP G+ G  G+PG DG  G+PG EG  GE+G  G  G+ G  G PG RGVKG+ 
Sbjct: 659  GTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTS 718

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157
            G  G +GE GE G DG  G  GD GL G  G+ G PG RG+ GP G KG+ G  G  G P
Sbjct: 719  GNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPP 778

Query: 2158 GNPGQDSQ-----------ERGPKGETGDLGPM------------GVPGRDGVPGGPGET 2194
            G+ G+  +             GPKG  G  GP+            G PG +G  G PG  
Sbjct: 779  GSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSR 838

Query: 2195 GKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGP---AGPAGPP------------ 2239
            G+ G  G  G PG KG+ G  G PG  GE+G  G QGP    GP GPP            
Sbjct: 839  GERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHP 898

Query: 2240 ---GLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDD 2296
               G +G QG +GP G  G  G  G+ G  GPLG +G PG PGP G  G  G  G  G  
Sbjct: 899  GQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAK 958

Query: 2297 GRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPK---------GIRGRRGNSG 2347
            G   +G  G  GK+G  G  G+PGPKG PG+PG  G  G K         G  G RG  G
Sbjct: 959  GE--LGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLG 1016

Query: 2348 PPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCPCCYGPLECP 2397
            P G +G  G  G  GP GP G +G   ++     + KD  P   GPL  P
Sbjct: 1017 PAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPP 1066



 Score =  276 bits (707), Expect = 2e-73
 Identities = 160/358 (44%), Positives = 190/358 (53%), Gaps = 30/358 (8%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G  G +GP G  GP G PG  G  G PG +G  G  G  G  G +GF G PG  G KG R
Sbjct: 506  GAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQR 565

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157
            G   + G VG+ G  G DGE G +G PG +G+ G PG RG  GPRG  G  G  G+ G  
Sbjct: 566  G---DFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGID 622

Query: 2158 GNPGQDSQ-----ERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNK 2212
            G PG         E GP G+ G+ G  G+PG  G+ G PGE G     G  G PG  G+ 
Sbjct: 623  GAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPP---GNPGIPGLPGSD 679

Query: 2213 GGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRK 2272
            G  G PG EG  G +GAQGP G AGPPG  G +G+ G  G+ G  G  GE+G  G  G K
Sbjct: 680  GPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFK 739

Query: 2273 GE---------PGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGY---P 2319
            G+         PG PGP+G  G  GP+G+ G  G +G  GS G +GK G  G PGY   P
Sbjct: 740  GDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRP 799

Query: 2320 GPKGNPGEPGLNGTTGPKGIRGR------RGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
            GPKG+ G PG  G  G KG  G+       G  GPPG  G++G PG  G  GPKG+ G
Sbjct: 800  GPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVG 857



 Score =  275 bits (704), Expect = 4e-73
 Identities = 164/397 (41%), Positives = 200/397 (50%), Gaps = 44/397 (11%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQG------FQGCPGQR 2091
            G+ G +G +G  GP G  G  G RG+PG +GGPG+ GP G+ G +G        G PG+R
Sbjct: 953  GREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGER 1012

Query: 2092 GVKGSRG---FPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER 2148
            G  G  G    PG+ G  G +G  G  G  G++G PG +G+ G PG  G  GP G  G  
Sbjct: 1013 GPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPS 1072

Query: 2149 GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208
            G+ G +GD G PG     +G KG+ GD GP G PG  G  G PG  G +G  GRRGPPG 
Sbjct: 1073 GEEGDKGDVGAPGH----KGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGL 1128

Query: 2209 KGNKGG------------------PGQPGFEGE------QGTRGAQGPAGPAGPPGLIGE 2244
             G KG                   PG PG +GE       G  GA GP GP GP G  G 
Sbjct: 1129 FGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGT 1188

Query: 2245 QGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRG---PRGETGDDGRDGV 2301
             G+ G  G  GA G  GERG  G  G  G PG PGPKG IG +G   P G  G  G+ G 
Sbjct: 1189 PGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGP 1248

Query: 2302 -GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKG---D 2357
             G +G +G  G  G PG  GP G+PG  G++G+ G KG  G  G  GPPG  G+ G    
Sbjct: 1249 PGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGP 1308

Query: 2358 PGYPGPAGPKGNRGDSIDQCALIQSIKDKCPCCYGPL 2394
            PG  GP+G  G  G   ++ A  +   D  P   GP+
Sbjct: 1309 PGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPM 1345



 Score =  275 bits (704), Expect = 4e-73
 Identities = 158/345 (45%), Positives = 182/345 (52%), Gaps = 14/345 (4%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096
            +G+ G  GP+G +GP G  G  G  G  GD G PG +G  G  G  G  G PG RG  G 
Sbjct: 1051 TGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGH 1110

Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGD 2156
             G PG  G  G  G  GL G+ GD G+ G  G  G PG +G  GP GEKGE GDVG  G 
Sbjct: 1111 PGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGP 1170

Query: 2157 PGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPG 2216
             G PG     RGP+G TG  G  G+PG  G PG  GE G+ G  G  GPPGA G  G  G
Sbjct: 1171 HGAPGP----RGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKG 1226

Query: 2217 QPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPG 2276
              G +G+ G  GA GP G  GPPG  G +G  GP G  G  G PG+ G +G  G  GE G
Sbjct: 1227 DIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKG 1286

Query: 2277 EPGPKGGIGNRGPRGETGDDGRDGV----GSEGRRGKKGERGFPGYPGPKGNPGEPGLNG 2332
            +PG  GG G  G  GE G  G  G     G  GR G++GE+G  G PGP G PG  G  G
Sbjct: 1287 DPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMG 1346

Query: 2333 T------TGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
                    GP+G+RG  G  G PG++G  G  G PGP GP G  G
Sbjct: 1347 ARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPG 1391



 Score =  273 bits (697), Expect = 3e-72
 Identities = 171/400 (42%), Positives = 205/400 (51%), Gaps = 68/400 (17%)

Query: 2037 SGQRGDRGPIGSIGPKG---IPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGV 2093
            +GQ G+ GP GS G KG   +PG  GY G PG +G  G  GP G  G +G  G  GQ G+
Sbjct: 769  AGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGL 828

Query: 2094 KGSRGFPGEKGEVGEIGLDGLDGEDGD---KGLPGSSGEKGNPGRR------GDKGPRGE 2144
            +G RG PG +GE G+ G  G  G  GD    G PG  GEKG PG +      G KGP G 
Sbjct: 829  EGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGH 888

Query: 2145 K---------GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETG 2195
            +         G+RG++G +G  G PG  +   GP+G+TG++GP+G  G  G PG PGE G
Sbjct: 889  QGKDGRPGHPGQRGELGFQGQTGPPG-PAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQG 947

Query: 2196 KNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGG 2255
              G  GR    GAKG  G PG  G EG  G RG  GP G  G PG  G +G  GP G  G
Sbjct: 948  LPGLEGRE---GAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVG 1004

Query: 2256 AAGAPGERGRTGPLGRKGEPGEP------GPKGGIGNRGPRGETGDDGRDGV-------- 2301
            A G+PGERG  GP G  G PG+       GP G  G+RG RG  G  G+DG+        
Sbjct: 1005 ANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLG 1064

Query: 2302 -----GSEGRRGKKGERGFPGYPGPKGN------PGEPGLNGTT---GPKGIRGRRGNSG 2347
                 G  G  G KG+ G PG+ G KG+      PG+PG+ G     GP G  G +G  G
Sbjct: 1065 PPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRG 1124

Query: 2348 PPGIVGQKGD---------------PGYPGPAGPKGNRGD 2372
            PPG+ GQKGD                G PGP G KG  GD
Sbjct: 1125 PPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGD 1164



 Score =  271 bits (694), Expect = 6e-72
 Identities = 165/368 (44%), Positives = 187/368 (50%), Gaps = 33/368 (8%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPG---QRGVK 2094
            GQRG+ G  G  GP G  G  G +G  G+ G  GERGPPG  G  G QG PG   + G K
Sbjct: 899  GQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAK 958

Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154
            G  G PG  G+ G  GL G  G  G  G PG +G KG+ G  G  G  G  GERG +G  
Sbjct: 959  GELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPA 1018

Query: 2155 GDPGNPGQDSQE-----RGPKGETGDLGPMGVPGRDGVPGG------PGETGKNGGFGRR 2203
            G  G PGQ   E      G KG  G+ GP G  G+DG+PG       PG  G +G  G +
Sbjct: 1019 GGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDK 1078

Query: 2204 GPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGP------------R 2251
            G  GA G+KG  G  G  G  G  G +GPAG  GPPG  G QG  GP            R
Sbjct: 1079 GDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVR 1138

Query: 2252 GSGGAAGAPGERGRTGPLGRKGEPGE---PGPKGGIGNRGPRGETGDDGR----DGVGSE 2304
            G  G  G PG +G  GP G KGE G+    GP G  G RGP+G TG +G      GVG  
Sbjct: 1139 GFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQP 1198

Query: 2305 GRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPA 2364
            G  G+KGERG  G PGP G PG PG  G  G KG  G  G +GPPG  G  G+ G  G  
Sbjct: 1199 GAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSV 1258

Query: 2365 GPKGNRGD 2372
            GP G  GD
Sbjct: 1259 GPTGLPGD 1266



 Score =  271 bits (693), Expect = 8e-72
 Identities = 154/359 (42%), Positives = 186/359 (51%), Gaps = 24/359 (6%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096
            +G +GD+GP G +G  G PGE G  G  G  G PG+ G  G  G  G +G  G+RG  G 
Sbjct: 991  TGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGP 1050

Query: 2097 RG---FPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI 2153
             G    PG  G +G  G  G  GE+GDKG  G+ G KG+ G +GD GP G+ G RG  G 
Sbjct: 1051 TGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGH 1110

Query: 2154 RGDPGNPGQDSQ--------ERGPKGETGDLGPMGVPGRDGVPGGPGETGK--------- 2196
             G PG  G   +        ++G  G  G +G +G PG  G+PG PGE G+         
Sbjct: 1111 PGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGP 1170

Query: 2197 NGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGA 2256
            +G  G RGP G  G++G PG PG  G+ G  G +G  G AG PG  G  GI GP+G  G 
Sbjct: 1171 HGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGE 1230

Query: 2257 AGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV----GSEGRRGKKGE 2312
             G  G  G  GP G+KG PGE G KG +G  G  G+ G  G  GV    GS G +G  G+
Sbjct: 1231 KGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGD 1290

Query: 2313 RGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
             G PG PG  G PG PG  G  GP G  GR G  G  G  G+ G  G PG  GP G RG
Sbjct: 1291 VGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARG 1349



 Score =  270 bits (691), Expect = 1e-71
 Identities = 169/410 (41%), Positives = 198/410 (48%), Gaps = 78/410 (19%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGE---------DGYRGYPGDEGGPGERGPPGVNGTQGFQGC 2087
            +GQ G+ GP G +GP+G PG          DG  G  G+ G PGE GPPG  G  G QG 
Sbjct: 592  TGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGL 651

Query: 2088 PGQRGVKGSRGFPGEKGEVGEIGLDGLDGED------------------------GDKGL 2123
            PG +G+ G+   PGEKG  G  G+ GL G D                        G  G 
Sbjct: 652  PGPQGLIGT---PGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGY 708

Query: 2124 PGSSGEKGNPGRRGDKGPRGEKGE------RGDVGIRGDPGNPGQ--------------- 2162
            PG  G KG  G RG +G +GEKGE      +GDVG++GD G PG                
Sbjct: 709  PGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQ 768

Query: 2163 --DSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGF 2220
               + E GP G  G+ G +GVPG  G PG PG  G  G  G  GP G KG  G  GQPG 
Sbjct: 769  AGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGL 828

Query: 2221 EGE------QGTRGAQGPAGPAGPPGLIGEQ---GISGPRGSGGAAGAPGERGRTGPLGR 2271
            EGE      +G RG  G  G  GP G +G+    GI G +G  G  G PG  G  GP G 
Sbjct: 829  EGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGH 888

Query: 2272 KGEPGEPGPKGGIGNRGPRGETGDDGRDGV----GSEGRRGKKGERGFPGYPGPKGNPGE 2327
            +G+ G PG  G  G  G +G+TG  G  GV    G  G  G  GERG PG PGP G  G 
Sbjct: 889  QGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGL 948

Query: 2328 PGL------NGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
            PGL       G  GP G  G+ G +G  G  G KG PG PGP G KG++G
Sbjct: 949  PGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKG 998



 Score =  270 bits (690), Expect = 2e-71
 Identities = 156/345 (45%), Positives = 184/345 (53%), Gaps = 29/345 (8%)

Query: 2040 RGDRGPIGSIG---PKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096
            +G  GP+G  G   P G+PG  G +G  G EG  G RG  G +G  G  G  G+ G  G+
Sbjct: 478  KGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGA 537

Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGD 2156
            RG PG+ G  G+ G DGL G  G+KG  G  G  G PG  G+ G RG +G  G  G  G+
Sbjct: 538  RGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGE 597

Query: 2157 PGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPG 2216
            PG        RG  G  G  GP G PG  G+ G PG  G  G  G  GPPG +GN G  G
Sbjct: 598  PG-------PRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQG 650

Query: 2217 QPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPG 2276
             PG +G  GT G +GP G  G PGL    G  GP G  G  G  GE+G  GP G  G PG
Sbjct: 651  LPGPQGLIGTPGEKGPPGNPGIPGL---PGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPG 707

Query: 2277 EPGP---KGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGLNG 2332
             PGP   KG  GNRG +GE G+ G DG  G +G  G KG++G PG PGP+G       +G
Sbjct: 708  YPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGE------DG 761

Query: 2333 TTGPKGIRGRRGNSGPPGIVGQKGD------PGYPGPAGPKGNRG 2371
              GPKG  G+ G  GPPG  G+KG       PGYPG  GPKG+ G
Sbjct: 762  PEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIG 806



 Score =  267 bits (683), Expect = 1e-70
 Identities = 152/354 (42%), Positives = 182/354 (51%), Gaps = 22/354 (6%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQ------- 2090
            G  GD GP G  G  G+PG  G +G  GD G  G+ GPPG +G +G +G PG        
Sbjct: 539  GLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEP 598

Query: 2091 --RGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER 2148
              RG+ G RG PG  G  G  G+DG  G  G+ G PG  G  G  G  G +G  G +G  
Sbjct: 599  GPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLI 658

Query: 2149 GDVGIRGDPGNPGQDS--------QERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGF 2200
            G  G +G PGNPG              G +G TG+ G  G PG  G PG PG  G  G  
Sbjct: 659  GTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTS 718

Query: 2201 GRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAP 2260
            G RG  G KG KG  G PGF+G+ G +G QG  G  GP G  G +G  G  G  G  G P
Sbjct: 719  GNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPP 778

Query: 2261 ---GERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPG 2317
               GE+G+ G  G  G PG PGPKG IG  GP G  G+ G+   G  G+ G +GERG PG
Sbjct: 779  GSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKS--GKTGQPGLEGERGPPG 836

Query: 2318 YPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
              G +G PG  G  G  G  G  G  G  G  G+ G +G PG+PGP GP G++G
Sbjct: 837  SRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQG 890



 Score =  247 bits (631), Expect = 1e-64
 Identities = 153/342 (44%), Positives = 179/342 (52%), Gaps = 30/342 (8%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGI------PGEDGYRGYPGDEGGPGERGPPGVNGTQGFQG 2086
            P    G RG +GP GS G  G+      PG  G +G  GD G PG  G PG+ G +G  G
Sbjct: 1170 PHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIG 1229

Query: 2087 CPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKG 2146
              G  G  G+ G PG+KG  GE   DG  G  G  GLPG  G  G+PG  G  G  GEKG
Sbjct: 1230 EKGDSGPSGAAGPPGKKGPPGE---DGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKG 1286

Query: 2147 ERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPP 2206
            + GDVG  G PG  G+     GP G+ G  G MG  GR+G  G  GE G +G  GR GP 
Sbjct: 1287 DPGDVGGPGPPGASGEPGAP-GPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPM 1345

Query: 2207 GAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRT 2266
            GA+      G PG  G +G RG     GP G PGL+G  G  GP G  G +G PG +G T
Sbjct: 1346 GAR------GPPGRVGPEGLRGI---PGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDT 1396

Query: 2267 GPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPG 2326
            GP   KGE G  G  G IG  G  GE GD G  GV     +G  G +G PG PGP G+ G
Sbjct: 1397 GP---KGEKGHIGLIGLIGPPGEAGEKGDQGLPGV-----QGPPGPKGDPGPPGPIGSLG 1448

Query: 2327 EPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKG 2368
             PG  G  GP    G++G+ G PG +G +GD G  GP GP G
Sbjct: 1449 HPGPPGVAGP---LGQKGSKGSPGSMGPRGDTGPAGPPGPPG 1487



 Score =  244 bits (624), Expect = 8e-64
 Identities = 151/362 (41%), Positives = 176/362 (48%), Gaps = 51/362 (14%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPG-------Q 2090
            G  G  GP G +GP G PG  G+   PGD G PG  G PG+ G  G +G PG       Q
Sbjct: 392  GPPGAPGPQGVVGPSGPPGPPGF---PGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQ 448

Query: 2091 RGVKGSRGFP-----------------GEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNP 2133
                  +G P                   KG  G +GL G     G  GLPG  G KG  
Sbjct: 449  FAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTG---RPGPVGLPGHPGLKGEE 505

Query: 2134 GRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGE 2193
            G  G +GPRG +G  G  G  G  G PG D    G +G  GD GP G  G DG+PG PGE
Sbjct: 506  GAEGPQGPRGLQGPHGPPGRVGKMGRPGAD----GARGLPGDTGPKGDRGFDGLPGLPGE 561

Query: 2194 TGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGS 2253
             G+ G FG              GQPG  GE G RGA+GP GP G  G  G +G+ GPRGS
Sbjct: 562  KGQRGDFGH------------VGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGS 609

Query: 2254 GGAAGAPGERGRTGPLGRKGE---PGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKK 2310
             G  G PG  G  G  G KG    PGEPGP G  GN G +G  G  G   +G+ G +G  
Sbjct: 610  PGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGL--IGTPGEKGPP 667

Query: 2311 GERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNR 2370
            G  G PG PG  G  G PG  G TG KG +G  G++GPPG  G +G  G  G  G +G +
Sbjct: 668  GNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEK 727

Query: 2371 GD 2372
            G+
Sbjct: 728  GE 729



 Score =  186 bits (471), Expect = 4e-46
 Identities = 134/350 (38%), Positives = 159/350 (45%), Gaps = 58/350 (16%)

Query: 2065 GDEG--GPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPG--EKGEVGEIGLDGLDGEDGD 2120
            GD+   GP  R     + TQ FQ  PG  G KG++G P   EKG+  E    G  G  G 
Sbjct: 346  GDDSTMGPDFRAAEYPSRTQ-FQIFPGA-GEKGAKGEPAVIEKGQQFE----GPPGAPGP 399

Query: 2121 KGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQ---------DSQERGP-- 2169
            +G+ G SG  G PG  GD GP G  G  G  GI G  G PG              +GP  
Sbjct: 400  QGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPV 459

Query: 2170 ------------------KGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGN 2211
                              KG  G +G  G PG  G+PG PG  G+ G  G +GP G +G 
Sbjct: 460  SFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGP 519

Query: 2212 KGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGR 2271
             G PG+ G  G  G  GA+G  G  GP          G RG  G  G PGE+G+ G  G 
Sbjct: 520  HGPPGRVGKMGRPGADGARGLPGDTGP---------KGDRGFDGLPGLPGEKGQRGDFGH 570

Query: 2272 KGEPGEPGPKGGIGNRGPRGETGDDGRDGV-------GSEGRRGKKGERGFPGYPGPKGN 2324
             G+PG PG  G  G  GP G TG  G  G        GS G  G+ G  G  G PG KGN
Sbjct: 571  VGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGN 630

Query: 2325 PGEPGLNGTTGPKGIRGRRGNSGPPGIV---GQKGDPGYPGPAGPKGNRG 2371
             G PG  G  G +G  G +G  GP G++   G+KG PG PG  G  G+ G
Sbjct: 631  VGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDG 680



 Score =  136 bits (343), Expect = 3e-31
 Identities = 89/227 (39%), Positives = 100/227 (44%), Gaps = 39/227 (17%)

Query: 2183 GRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLI 2242
            G  G  G P    K   F   GPPGA G +G  G  G  G  G  G  GP GPAG PG+ 
Sbjct: 373  GEKGAKGEPAVIEKGQQF--EGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIP 430

Query: 2243 GEQGISGPRGS------------------------------------GGAAGAPGERGRT 2266
            G  GI GP G+                                     G  G  G  GR 
Sbjct: 431  GIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRP 490

Query: 2267 GPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNP 2325
            GP+G  G PG  G +G  G +GPRG  G  G  G VG  GR G  G RG PG  GPKG+ 
Sbjct: 491  GPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDR 550

Query: 2326 GEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
            G  GL G  G KG RG  G+ G PG  G+ G+ G  GP GP G  G+
Sbjct: 551  GFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGE 597


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score =  282 bits (721), Expect = 4e-75
 Identities = 166/361 (45%), Positives = 191/361 (52%), Gaps = 39/361 (10%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGD------EGGPGERGPPGVNGTQGFQGCPGQR 2091
            G RG  GP G IG +G+PG  G +G  GD       G PG RGP G NG  G QG PG  
Sbjct: 1058 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG-- 1115

Query: 2092 GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD- 2150
            GV G+ G PGEKGE GE G  G+ GE G KG  G  GEKG  G+ G+ GP G KG  GD 
Sbjct: 1116 GV-GNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD 1174

Query: 2151 --------VGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGR 2202
                    VG  GDPG PG+    RG  G  GD G  G PG+ G PG  GE G  G  G+
Sbjct: 1175 GPKGNPGPVGFPGDPGPPGEGGP-RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGK 1233

Query: 2203 RGP---PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGA 2259
            RGP   PG++G +GG G  G  G  G  G  GP GPAGP G  G  G+ G  GS G  G 
Sbjct: 1234 RGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGR 1293

Query: 2260 PGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYP 2319
            PG  G+ GP G  G PG PG +G  G +G +G  G  G   +G  G +G+KG+RG PG  
Sbjct: 1294 PGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL--IGPPGEQGEKGDRGLPGPQ 1351

Query: 2320 GPKGNPGE---------------PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPA 2364
            G  G  GE               PGL G  GPKG +G  G  GP G  G +G PG+PGP 
Sbjct: 1352 GSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPP 1411

Query: 2365 G 2365
            G
Sbjct: 1412 G 1412



 Score =  281 bits (719), Expect = 7e-75
 Identities = 160/348 (45%), Positives = 190/348 (54%), Gaps = 17/348 (4%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G+ G  GP G IGP G PG  G  G PG  G  G  G  G  GT+GF G PG  G++G  
Sbjct: 1016 GEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLP 1075

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPG---SSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154
            G  GEKGE G++G  G  G  G +G  G   + G +G PG  G+ GP GEKGE G+ G  
Sbjct: 1076 GPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSP 1135

Query: 2155 GDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGG 2214
            G  G PG     +GP+GE G+ G  G PG  G PG  G TG +G  G  GP G  G+ G 
Sbjct: 1136 GIQGEPGV----KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGP 1191

Query: 2215 PGQPGFEGEQGT---RGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGR 2271
            PG+ G  G+ G    RG  G  G  G PG  GE G  GP G  G AG+PG  GR G  G 
Sbjct: 1192 PGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGA 1251

Query: 2272 KGEPGE---PGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGE 2327
            KG+PG    PG  G +G  GP G+ G DG  G+ GS G++G+ G  G  G PGP G PG 
Sbjct: 1252 KGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGL 1311

Query: 2328 PGLNGTTGPKGIRGRRGNSG---PPGIVGQKGDPGYPGPAGPKGNRGD 2372
            PGL G  G KG +G  G  G   PPG  G+KGD G PGP G  G +G+
Sbjct: 1312 PGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGE 1359



 Score =  281 bits (718), Expect = 9e-75
 Identities = 173/398 (43%), Positives = 198/398 (49%), Gaps = 65/398 (16%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERG---------------PPGVNGTQ 2082
            G  G++GP G  G  G+PG DG  G+PG EG PG +G               P GV G  
Sbjct: 581  GPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVD 640

Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVG------EIGLDGLDGEDG------------DKGLP 2124
            G +G  G +G KG  GFPG KG++G      E+G+ G  GEDG            D G P
Sbjct: 641  GIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPP 700

Query: 2125 GSSGEKGN---------PGRRGDKGP---------RGEKGER---GDVGIRGDPGNPGQD 2163
            G  GEKG          PGR+G KG           GEKG R   G  G RG+ G  G  
Sbjct: 701  GLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPR 760

Query: 2164 SQERGPKGETGDLGPMGVPGRDGVPGGPGE------TGKNGGFGRRGPPGAKGNKGGPGQ 2217
             Q RGP+G TG  G  G  G DG  G PGE       G NG  G +GPPG  G  G PG 
Sbjct: 761  GQ-RGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGH 819

Query: 2218 PGFEGEQGTRGAQGPAGP---AGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGE 2274
            PG  GE G +G  GP GP    GP G  GE G  G RG  G  G PGE+G  G  G++G 
Sbjct: 820  PGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 879

Query: 2275 PGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGT 2333
             G+PGP G  G  GP G  G  G  G+ G+ G  G KG  G  G PGP G+PGE G  G+
Sbjct: 880  KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 939

Query: 2334 TGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
             GP G  GR G  GPPG  G+KG PG  GP GP G  G
Sbjct: 940  GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDG 977



 Score =  279 bits (714), Expect = 3e-74
 Identities = 161/349 (46%), Positives = 193/349 (55%), Gaps = 21/349 (6%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERG---PPGVNGTQGFQGCPGQRGVK 2094
            G  G +GP GS+GP+G PG  G +G PG +G PG +G   P G  G QG  G PG  G  
Sbjct: 542  GMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSD 601

Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGE------R 2148
            G  G PG++G  G  G  G  G  G  G PG  G KG  G RG KG +GEKGE      +
Sbjct: 602  GPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFK 661

Query: 2149 GDVGIRGD------PGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGR 2202
            GD+G++GD      PG+ G+D  E GPKG TG  G  G PG  G  G  G  G  G  GR
Sbjct: 662  GDIGVKGDRGEVGVPGSRGEDGPE-GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR 720

Query: 2203 RGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE 2262
            +GP   KG+ G PG PG  GE+G RG  G +GP G  G  G +G  GPRG+ G +GA G 
Sbjct: 721  QGP---KGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGT 777

Query: 2263 RGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPK 2322
             G  GP G  GE G PGP+G  G  GP+G  G  G+DG+   G  G++GE GF G  GP 
Sbjct: 778  SGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL--PGHPGQRGEVGFQGKTGPP 835

Query: 2323 GNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
            G PG  G  G  G  G  G RG+ GPPG  G++G PG  G  G KG+ G
Sbjct: 836  GPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPG 884



 Score =  278 bits (712), Expect = 5e-74
 Identities = 162/365 (44%), Positives = 185/365 (50%), Gaps = 26/365 (7%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGV---NGTQGFQGCPG 2089
            P   +G+ G  G  G  GP G PGE G  G  G EG  G+ GPPG    +G  G +G PG
Sbjct: 843  PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG 902

Query: 2090 QRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERG 2149
            +RG+ G+ G PG KG  G  G  G  G  G++G  GS G  G PGR G +GP G  GE+G
Sbjct: 903  ERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKG 962

Query: 2150 DVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPG---GPGETGKNGGFGRRGPP 2206
              G +G  G  G+D  + GP G  G  GP GV G DG  G    PG+ G  G  G  GPP
Sbjct: 963  VPGEKGPIGPTGRDGVQ-GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPP 1021

Query: 2207 GAKGNKGGPGQPGFEGEQGTRGAQGPAGPAG------------PPGLIGEQGISGPRGSG 2254
            G  G  G  GQPG  G  G  GA+GP G  G            PPG IG QG+ GP G  
Sbjct: 1022 GPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEK 1081

Query: 2255 GAAG------APGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRR 2307
            G  G       PG  G  GP G  G  G  GP GG+GN GP GE G+ G  G  G +G  
Sbjct: 1082 GETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEP 1141

Query: 2308 GKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPK 2367
            G KG RG  G  G  G PGEPG  G  GP G  G +GN GP G  G  G PG  GP G  
Sbjct: 1142 GVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQD 1201

Query: 2368 GNRGD 2372
            G +GD
Sbjct: 1202 GAKGD 1206



 Score =  278 bits (710), Expect = 8e-74
 Identities = 161/357 (45%), Positives = 188/357 (52%), Gaps = 27/357 (7%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGV--- 2093
            SG++G RG  G  GP+G  G  G RG  G  G  G+ G  G +G  G  G PG+RG+   
Sbjct: 736  SGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGP 795

Query: 2094 KGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI 2153
            +G  GFPG KG  G  G DGL G  G +G  G  G+ G PG  G  GP+G  GE G +G 
Sbjct: 796  QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 855

Query: 2154 RGDPGNPGQDSQE-----RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208
            RG PG PG   ++      G +G  GD GP G PG+DG  G  G  G+ G  G  G PG 
Sbjct: 856  RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGL 915

Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2268
            KGN+G  G PG  G  G RGA G  GP GPPG  G Q   GP G+ G  G PGE+G  GP
Sbjct: 916  KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQ---GPPGAAGEKGVPGEKGPIGP 972

Query: 2269 LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGE 2327
             GR G  G  G  G  G  G  GE GD G  G  G +G +G KGE G PG PGP G  G+
Sbjct: 973  TGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQ 1032

Query: 2328 PGLNGTTGPKGIR------------GRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
            PG  G  G  G R            G RG +GPPG +G +   G PGP+G KG  GD
Sbjct: 1033 PGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ---GLPGPSGEKGETGD 1086



 Score =  272 bits (695), Expect = 4e-72
 Identities = 154/344 (44%), Positives = 188/344 (54%), Gaps = 30/344 (8%)

Query: 2043 RGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGE 2102
            RGP G +G  G PG  G  G PG +G  G+ GP G  G QG  G PG+ G +G  G  G 
Sbjct: 400  RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 459

Query: 2103 KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQ 2162
            +G  G+ G+ G  G DG  GLPG  G +G+ G +G  GP GE GERGD G          
Sbjct: 460  RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDG---------- 509

Query: 2163 DSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEG 2222
               E GP+G  G+ GP G+ G  G PG PG  G  G  G +GP G+ G +G PG PG +G
Sbjct: 510  ---EIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQG 566

Query: 2223 EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKG 2282
              GT+G  GP G  GP G  G QG  G  G  G+ G PG  G+ GP G KG  G  GP+G
Sbjct: 567  TPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQG 626

Query: 2283 GIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYP---------GPKGNPGEPGLNGT 2333
             +G  GPRG  G DG  G+  +G +G+KGE GFPG+          G  G PG  G +G 
Sbjct: 627  PLGYPGPRGVKGVDGIRGL--KGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGP 684

Query: 2334 TGPKGIRGRRGNSGPPGIVGQKGD------PGYPGPAGPKGNRG 2371
             GPKG  G  G+ GPPG++G+KG       PGYPG  GPKG+ G
Sbjct: 685  EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLG 728



 Score =  270 bits (690), Expect = 2e-71
 Identities = 157/393 (39%), Positives = 198/393 (50%), Gaps = 57/393 (14%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDG---YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094
            G  G  G  G  GP G PG+DG    RG+PG+ G PG  G PG+ G +G  G PG  G  
Sbjct: 872  GTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 931

Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI- 2153
            G RG  G  G +G        G  G +G PG++GEKG PG +G  GP G  G +G VG+ 
Sbjct: 932  GERGAAGSGGPIGP------PGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLP 985

Query: 2154 --------------RGDPGNPGQ-----DSQERGPKGETGDLGPMGVPGRDGVPGGPGET 2194
                          +G+ G+PGQ     +  E GP G  G +GP+G PG  G  G PG  
Sbjct: 986  GPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGAR 1045

Query: 2195 GKNGGFGRRGPPGAKGNKGGPGQPGFEG---EQGTRGAQGPAGPAGPPGLIGEQGISGPR 2251
            G  G FG +G  G +G  G PG  G +G     G +G  G  GP GPPG  G +G +GP 
Sbjct: 1046 GPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPN 1105

Query: 2252 GSGGAAGAPGERGRTGPLGRKGEPGE---PGPKGGIGNRGPRGETGDDGRDGV----GSE 2304
            G+ G  G PG  G  GP G KGEPGE   PG +G  G +GPRGE G+ G  G     G  
Sbjct: 1106 GADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1165

Query: 2305 GRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGN------------------S 2346
            G +G  G+ G  G PGP G PG+PG  G  GP+G  G +G+                  +
Sbjct: 1166 GPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGEN 1225

Query: 2347 GPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCAL 2379
            GPPG +G++G  G PG  G +G +G   D  A+
Sbjct: 1226 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAI 1258



 Score =  270 bits (689), Expect = 2e-71
 Identities = 164/375 (43%), Positives = 189/375 (50%), Gaps = 44/375 (11%)

Query: 2040 RGDRGPIGSIG---PKGIPGEDGYRGYPGDEGGPGERGPPGVNG------------TQGF 2084
            RG  GP+G  G   P G PG  G +G  GD G  G RGP G+ G              G 
Sbjct: 400  RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 459

Query: 2085 QGCPGQRGVKGSRGF------PGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGD 2138
            +G PG  GVKG RGF      PGEKG  G+ G  GL G  G+ G  G  GE G  G  G+
Sbjct: 460  RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 519

Query: 2139 KGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGG---PGETG 2195
             GPRG  G +G  GI G PG  G D  + GPKG  G  G  G PG+ G PG    PG  G
Sbjct: 520  SGPRGLLGPKGPPGIPGPPGVRGMDGPQ-GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQG 578

Query: 2196 KNGGFGRRGP------PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGP---------PG 2240
              G  G +GP      PG  G+ G PG PG EG  GT+G QGP+GP GP          G
Sbjct: 579  AIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKG 638

Query: 2241 LIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG 2300
            + G +G+ G +G  G  G PG +G  G  G +GE G PG +G  G  GP+G TG  G  G
Sbjct: 639  VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG 698

Query: 2301 V-GSEGRRGKKGERGFPGYP---GPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKG 2356
              G  G +GK G  G PGYP   GPKG+ G PG  G +G KG RG  G SGP G  G  G
Sbjct: 699  PPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTG 758

Query: 2357 DPGYPGPAGPKGNRG 2371
              G  GP G  G  G
Sbjct: 759  PRGQRGPRGATGKSG 773



 Score =  269 bits (688), Expect = 3e-71
 Identities = 162/381 (42%), Positives = 192/381 (50%), Gaps = 40/381 (10%)

Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGG------PGERGPPGV---NGT 2081
            G P    G+ G +GP G+ G KG+PGE G  G  G +G       PG  GPPGV   +G 
Sbjct: 940  GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGD 999

Query: 2082 QGFQGCPGQRGVKGSRGF------PGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGR 2135
            +G  G PGQ+G KG++G       PG  G VG+ G  G DGE G +G  G  G KG+ G 
Sbjct: 1000 KGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGT 1059

Query: 2136 RGDKGP------------RGEKGERGDVGIRGDPGNPGQ-----DSQERGPKGETGDLGP 2178
            RG  GP             GEKGE GDVG  G PG PG       +   GP+G  G +G 
Sbjct: 1060 RGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN 1119

Query: 2179 MGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGP 2238
            +G PG  G PG  G  G  G  G +GP G +G KG  GQPG  G  G +G  G  GP G 
Sbjct: 1120 LGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN 1179

Query: 2239 PGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGG------IGNRGPRGE 2292
            PG +G  G  GP G GG  G  G +G  G  G  G+PG PGP G       +G RGP G 
Sbjct: 1180 PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1239

Query: 2293 TGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIV 2352
             G +GR G   +G +G  G  G PG  GP G  G  G  G  G +G+ G  G  G PG  
Sbjct: 1240 PGSEGRQG--GKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGAT 1297

Query: 2353 GQKGDPGYPGPAGPKGNRGDS 2373
            GQ G PG  GP G  G RGD+
Sbjct: 1298 GQAGPPGPVGPPGLPGLRGDA 1318



 Score =  266 bits (681), Expect = 2e-70
 Identities = 160/377 (42%), Positives = 195/377 (51%), Gaps = 50/377 (13%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G+ G+RG  G IGP+G+PGE G RG  G +G PG  GPPGV G  G QG  G  G +G  
Sbjct: 500  GEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEP 559

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157
            G PG++G  G  GL G  G  G  G  G  G+ G PG  G  GP G  G+ G  G +G+ 
Sbjct: 560  GPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQ 619

Query: 2158 GNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQ 2217
            G  G     +GP G  G  G  GV G  G+ G  GE G++G  G +G  G KG++G  G 
Sbjct: 620  GPSGP----QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV 675

Query: 2218 PGFEGE---QGTRGAQGPAGPAGPPGLIGEQGI------------SGPRGSGGAAGAPG- 2261
            PG  GE   +G +G  GP G  GPPGL+GE+G              GP+GS G  G PG 
Sbjct: 676  PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGA 735

Query: 2262 --ERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPG- 2317
              E+G  G  G+ G  GE GP G  G RGPRG TG  G  G  G +G  G  GERG PG 
Sbjct: 736  SGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGP 795

Query: 2318 -----YPGPKGN---------PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK-------- 2355
                 +PGPKG          PG PG  G     G +G+ G  GPPG+VG +        
Sbjct: 796  QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEV---GFQGKTGPPGPPGVVGPQGAAGETGP 852

Query: 2356 -GDPGYPGPAGPKGNRG 2371
             G+ G+PGP GP G +G
Sbjct: 853  MGERGHPGPPGPPGEQG 869



 Score =  263 bits (673), Expect = 2e-69
 Identities = 160/395 (40%), Positives = 195/395 (49%), Gaps = 57/395 (14%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQR- 2091
            P   +G+ G +G  G  GP G PGE G  G  G  G PG +GPPG  G  G  G PGQR 
Sbjct: 765  PRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRG 824

Query: 2092 --------------GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRG 2137
                          GV G +G  GE G +GE G  G  G  G++GLPG++G++G    +G
Sbjct: 825  EVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT---KG 881

Query: 2138 DKGPRGEKGERGDVGIRGDPGNPGQDSQERGP-----KGETGDLGPMGVPGRDGVPGGPG 2192
            D GP G  G+ G  G+RG PG  G      GP     +G +G  GP G PG  G  G  G
Sbjct: 882  DPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGG 941

Query: 2193 ETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPA---GPAGPPGLIGEQGISG 2249
              G  G  G +GPPGA G KG PG+ G  G  G  G QGP    GPAGPPG+ GE G  G
Sbjct: 942  PIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 1001

Query: 2250 PRGSGGAAGAPGERGR------TGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG--- 2300
              G  G  G  G +G        GP+G  G+PG  G  G  G RGP+G  G  G +G   
Sbjct: 1002 EVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRG 1061

Query: 2301 -------VGSEGRRGKKGERGFPGYPGPKGNPGEP------GLNGTTGPKGIRGRRGNSG 2347
                   +G +G  G  GE+G  G  GP G PG P      G NG  GP+G  G  GN G
Sbjct: 1062 FNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLG 1121

Query: 2348 PPGIVGQ---------KGDPGYPGPAGPKGNRGDS 2373
            PPG  G+         +G+PG  GP G +G +G+S
Sbjct: 1122 PPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGES 1156



 Score =  241 bits (616), Expect = 6e-63
 Identities = 148/362 (40%), Positives = 178/362 (49%), Gaps = 35/362 (9%)

Query: 2044 GPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK-------GS 2096
            GP G  GP G+ G  G +G PG  G PGERGPPG  G  G  G PG  G         GS
Sbjct: 313  GPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGS 372

Query: 2097 RGFPGEKGEV--------------GEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142
             G  G+KG V                + L G  G  G  G PG  G+ G+PG +G+ G  
Sbjct: 373  GG--GDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 430

Query: 2143 GEKGERGDVGIRGDPGNPGQDSQER--GPKGETGDLGPMGVPGRDGVPGGPGETGKNGGF 2200
            G +G RG  G+ G PG  G+  +    G +G  GD G  G  G DG+PG PGE G  G  
Sbjct: 431  GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDT 490

Query: 2201 GRRG---PPGAKGNKGGPGQ---PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSG 2254
            G +G   PPG  G +G  G+    G  GE G RG  GP GP G PG  G +G+ GP+G  
Sbjct: 491  GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPK 550

Query: 2255 GAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV----GSEGRRGKK 2310
            G+ G  GE G  G  G  G  G PGP+G IG  G +G  G  G  G+    G  G  GK+
Sbjct: 551  GSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKE 610

Query: 2311 GERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNR 2370
            G  G  G  GP G  G  G  G  G KG+ G RG  G  G  G+ G PG+ G  G KG+R
Sbjct: 611  GPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDR 670

Query: 2371 GD 2372
            G+
Sbjct: 671  GE 672



 Score =  223 bits (569), Expect = 2e-57
 Identities = 139/347 (40%), Positives = 172/347 (49%), Gaps = 43/347 (12%)

Query: 2050 GPKGIPGEDG----------YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGF 2099
            GP+G+ GE G            G PG EG  G  GPPG+ G  G  G PG+RG  G  G 
Sbjct: 291  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 350

Query: 2100 PGEKGEVGEIGLDGL-----DGEDGDKGLPGSSGEKG-----NPGRRGDKGPRGEKGERG 2149
            PG  G  G  G   +         GDKG   ++ E          R   +GP G  G  G
Sbjct: 351  PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTG 410

Query: 2150 DVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAK 2209
              G  G PG+PG        KGE+GDLGP G  G  G+ G PG+ G      RRG  GA 
Sbjct: 411  RPGPLGQPGSPGL-------KGESGDLGPQGPRGPQGLTGPPGKAG------RRGRAGAD 457

Query: 2210 GNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPL 2269
            G +G PG PG +G++G  G  G  G  G  G  G QG+ GP G  G      ERG  G +
Sbjct: 458  GARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDG------ERGDDGEI 511

Query: 2270 GRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGE- 2327
            G +G PGE GP+G +G +GP G  G  G  G+ G +G +G  G +G PG PG +G PG  
Sbjct: 512  GPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQ 571

Query: 2328 --PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
              PG  G  GP G +G +G  G PG+ G  G PG+PG  GP G +G+
Sbjct: 572  GLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN 618



 Score =  189 bits (479), Expect = 5e-47
 Identities = 114/263 (43%), Positives = 133/263 (50%), Gaps = 26/263 (9%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G+ G  G  G  GPKG  G+DG +G PG  G PG+ GPPG  G +G  G  G RG  G  
Sbjct: 1154 GESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEP 1213

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKG------------PRGEK 2145
            G PG  G  GE G  G  G+ G  G PGS G +G  G +GD G            P G  
Sbjct: 1214 GQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA 1273

Query: 2146 GERGDVGIRGDPGNPGQDSQE--RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRR 2203
            G+ G  G+RG PG+ GQ  +    G  G  G +GP G+PG  G  G  GE G  G  G  
Sbjct: 1274 GKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLI 1333

Query: 2204 GPPGAKGNKG-----GP-GQPGFEGEQGTRGAQGP---AGPAGPPGLIGEQGISGPRGSG 2254
            GPPG +G KG     GP G PG +GE G  GA GP    GP   PGL G  G  G +G+ 
Sbjct: 1334 GPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP---PGLPGPAGPKGAKGAT 1390

Query: 2255 GAAGAPGERGRTGPLGRKGEPGE 2277
            G  G  GE+G  GP G  G PGE
Sbjct: 1391 GPGGPKGEKGVQGPPGHPGPPGE 1413



 Score =  171 bits (432), Expect = 1e-41
 Identities = 101/228 (44%), Positives = 118/228 (51%), Gaps = 10/228 (4%)

Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQ 2090
            G P    G +GDRG  G  G  G PG  G  G PG     G+RGP G  G++G QG  G 
Sbjct: 1195 GGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP---LGKRGPAGSPGSEGRQGGKGA 1251

Query: 2091 RGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD 2150
            +G  G+ G PG+ G VG  G  G  G DG +GLPGS G++G PG  G  GP G  G  G 
Sbjct: 1252 KGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGL 1311

Query: 2151 VGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKG 2210
             G+RGD G  G    E+G  G  G +GP G  G  G  G PG  G  G  G  G PGA G
Sbjct: 1312 PGLRGDAGAKG----EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASG 1367

Query: 2211 NKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAG 2258
              G  G PG  G  G +GA+G  GP GP    GE+G+ GP G  G  G
Sbjct: 1368 PIGPGGPPGLPGPAGPKGAKGATGPGGPK---GEKGVQGPPGHPGPPG 1412



 Score =  148 bits (373), Expect = 1e-34
 Identities = 97/241 (40%), Positives = 121/241 (50%), Gaps = 18/241 (7%)

Query: 2140 GPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGG 2199
            GPRG KGE+G+  +  +PG         GP G  G  G +G PG  G PG  G+ G+ G 
Sbjct: 291  GPRGLKGEKGEPAVL-EPG-----MLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGP 344

Query: 2200 FGRRGPPGAKGNKGGPGQP-----GFEGEQGTRGAQGPAGPAGPPGLIGEQGIS--GPRG 2252
             GR G PG+ G  G PG        F    G +G    A  A    ++ +  ++  GP G
Sbjct: 345  PGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPG 404

Query: 2253 SGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGE 2312
              G  G PG  G+ G  G KGE G+ GP+G    RGP+G TG  G+   G  GR G  G 
Sbjct: 405  PMGYTGRPGPLGQPGSPGLKGESGDLGPQGP---RGPQGLTGPPGK--AGRRGRAGADGA 459

Query: 2313 RGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
            RG PG PG KG+ G  GL G  G KG RG  G  G PG  G+ G+ G  G  GP+G  G+
Sbjct: 460  RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 519

Query: 2373 S 2373
            S
Sbjct: 520  S 520



 Score =  108 bits (271), Expect = 6e-23
 Identities = 67/164 (40%), Positives = 80/164 (48%), Gaps = 9/164 (5%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGT---QGFQGCPGQRGVK 2094
            GQ+G  G  G  GP G  G  G  G  GD G  GE+G PG+ G     G QG  G RG+ 
Sbjct: 1289 GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1348

Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154
            G +G PG+KGE+G  G  G  G  G  GLPG +G KG  G  G  GP+GEKG +G  G  
Sbjct: 1349 GPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHP 1408

Query: 2155 GDPGNPGQDSQERGPKGETGDLGPMGVPGRD------GVPGGPG 2192
            G PG   Q    + PK     +    +   D      G PG PG
Sbjct: 1409 GPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1452



 Score = 75.9 bits (185), Expect = 6e-13
 Identities = 61/190 (32%), Positives = 69/190 (36%), Gaps = 78/190 (41%)

Query: 2260 PGERGRTGPLGRKGEPGE-------------------------------PGPKGGIGNRG 2288
            P E    GP G KGE GE                               PGP G  G RG
Sbjct: 284  PLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 343

Query: 2289 PRGETGDDGRDGV--------------GSEG------------------------RRGKK 2310
            P G  G  G DG               GS G                         RG  
Sbjct: 344  PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPP 403

Query: 2311 GERGFPGYPGPKGNPGEPGLNGTT---GPKGIRGRRGNSGPPGIVGQKGDP------GYP 2361
            G  G+ G PGP G PG PGL G +   GP+G RG +G +GPPG  G++G        G P
Sbjct: 404  GPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMP 463

Query: 2362 GPAGPKGNRG 2371
            G  G KG+RG
Sbjct: 464  GDPGVKGDRG 473



 Score = 54.3 bits (129), Expect = 2e-06
 Identities = 32/76 (42%), Positives = 37/76 (48%), Gaps = 4/76 (5%)

Query: 2303 SEGRRGKKGERGFPGYPGP----KGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDP 2358
            + G RG KGE+G P    P    +G PG  G  G  GP GI+G  G  G PG  G  G  
Sbjct: 289  AHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA 348

Query: 2359 GYPGPAGPKGNRGDSI 2374
            G PG  G  G  G S+
Sbjct: 349  GLPGSDGAPGPPGTSL 364



 Score = 39.3 bits (90), Expect = 0.063
 Identities = 41/124 (33%), Positives = 48/124 (38%), Gaps = 31/124 (25%)

Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQ 2090
            G P    G  G +G  G+ GP G  GE G +G PG  G PGE            Q  P Q
Sbjct: 1372 GGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGE----------VIQPLPIQ 1421

Query: 2091 ------RGVKGSR-----------GFPGEKGEVGEI--GLDGLDGEDGDKGLPGSSGEKG 2131
                  R V GSR           G PG  G + EI   LD L  E      P  +G + 
Sbjct: 1422 MPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRP--TGTQD 1479

Query: 2132 NPGR 2135
            +P R
Sbjct: 1480 SPAR 1483


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score =  282 bits (721), Expect = 4e-75
 Identities = 166/361 (45%), Positives = 191/361 (52%), Gaps = 39/361 (10%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGD------EGGPGERGPPGVNGTQGFQGCPGQR 2091
            G RG  GP G IG +G+PG  G +G  GD       G PG RGP G NG  G QG PG  
Sbjct: 1037 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG-- 1094

Query: 2092 GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD- 2150
            GV G+ G PGEKGE GE G  G+ GE G KG  G  GEKG  G+ G+ GP G KG  GD 
Sbjct: 1095 GV-GNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD 1153

Query: 2151 --------VGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGR 2202
                    VG  GDPG PG+    RG  G  GD G  G PG+ G PG  GE G  G  G+
Sbjct: 1154 GPKGNPGPVGFPGDPGPPGEGGP-RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGK 1212

Query: 2203 RGP---PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGA 2259
            RGP   PG++G +GG G  G  G  G  G  GP GPAGP G  G  G+ G  GS G  G 
Sbjct: 1213 RGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGR 1272

Query: 2260 PGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYP 2319
            PG  G+ GP G  G PG PG +G  G +G +G  G  G   +G  G +G+KG+RG PG  
Sbjct: 1273 PGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL--IGPPGEQGEKGDRGLPGPQ 1330

Query: 2320 GPKGNPGE---------------PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPA 2364
            G  G  GE               PGL G  GPKG +G  G  GP G  G +G PG+PGP 
Sbjct: 1331 GSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPP 1390

Query: 2365 G 2365
            G
Sbjct: 1391 G 1391



 Score =  281 bits (719), Expect = 7e-75
 Identities = 160/348 (45%), Positives = 190/348 (54%), Gaps = 17/348 (4%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G+ G  GP G IGP G PG  G  G PG  G  G  G  G  GT+GF G PG  G++G  
Sbjct: 995  GEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLP 1054

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPG---SSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154
            G  GEKGE G++G  G  G  G +G  G   + G +G PG  G+ GP GEKGE G+ G  
Sbjct: 1055 GPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSP 1114

Query: 2155 GDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGG 2214
            G  G PG     +GP+GE G+ G  G PG  G PG  G TG +G  G  GP G  G+ G 
Sbjct: 1115 GIQGEPGV----KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGP 1170

Query: 2215 PGQPGFEGEQGT---RGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGR 2271
            PG+ G  G+ G    RG  G  G  G PG  GE G  GP G  G AG+PG  GR G  G 
Sbjct: 1171 PGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGA 1230

Query: 2272 KGEPGE---PGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGE 2327
            KG+PG    PG  G +G  GP G+ G DG  G+ GS G++G+ G  G  G PGP G PG 
Sbjct: 1231 KGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGL 1290

Query: 2328 PGLNGTTGPKGIRGRRGNSG---PPGIVGQKGDPGYPGPAGPKGNRGD 2372
            PGL G  G KG +G  G  G   PPG  G+KGD G PGP G  G +G+
Sbjct: 1291 PGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGE 1338



 Score =  281 bits (718), Expect = 9e-75
 Identities = 173/398 (43%), Positives = 198/398 (49%), Gaps = 65/398 (16%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERG---------------PPGVNGTQ 2082
            G  G++GP G  G  G+PG DG  G+PG EG PG +G               P GV G  
Sbjct: 560  GPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVD 619

Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVG------EIGLDGLDGEDG------------DKGLP 2124
            G +G  G +G KG  GFPG KG++G      E+G+ G  GEDG            D G P
Sbjct: 620  GIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPP 679

Query: 2125 GSSGEKGN---------PGRRGDKGP---------RGEKGER---GDVGIRGDPGNPGQD 2163
            G  GEKG          PGR+G KG           GEKG R   G  G RG+ G  G  
Sbjct: 680  GLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPR 739

Query: 2164 SQERGPKGETGDLGPMGVPGRDGVPGGPGE------TGKNGGFGRRGPPGAKGNKGGPGQ 2217
             Q RGP+G TG  G  G  G DG  G PGE       G NG  G +GPPG  G  G PG 
Sbjct: 740  GQ-RGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGH 798

Query: 2218 PGFEGEQGTRGAQGPAGP---AGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGE 2274
            PG  GE G +G  GP GP    GP G  GE G  G RG  G  G PGE+G  G  G++G 
Sbjct: 799  PGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 858

Query: 2275 PGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGT 2333
             G+PGP G  G  GP G  G  G  G+ G+ G  G KG  G  G PGP G+PGE G  G+
Sbjct: 859  KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 918

Query: 2334 TGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
             GP G  GR G  GPPG  G+KG PG  GP GP G  G
Sbjct: 919  GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDG 956



 Score =  279 bits (714), Expect = 3e-74
 Identities = 161/349 (46%), Positives = 193/349 (55%), Gaps = 21/349 (6%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERG---PPGVNGTQGFQGCPGQRGVK 2094
            G  G +GP GS+GP+G PG  G +G PG +G PG +G   P G  G QG  G PG  G  
Sbjct: 521  GMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSD 580

Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGE------R 2148
            G  G PG++G  G  G  G  G  G  G PG  G KG  G RG KG +GEKGE      +
Sbjct: 581  GPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFK 640

Query: 2149 GDVGIRGD------PGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGR 2202
            GD+G++GD      PG+ G+D  E GPKG TG  G  G PG  G  G  G  G  G  GR
Sbjct: 641  GDIGVKGDRGEVGVPGSRGEDGPE-GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR 699

Query: 2203 RGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE 2262
            +GP   KG+ G PG PG  GE+G RG  G +GP G  G  G +G  GPRG+ G +GA G 
Sbjct: 700  QGP---KGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGT 756

Query: 2263 RGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPK 2322
             G  GP G  GE G PGP+G  G  GP+G  G  G+DG+   G  G++GE GF G  GP 
Sbjct: 757  SGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL--PGHPGQRGEVGFQGKTGPP 814

Query: 2323 GNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
            G PG  G  G  G  G  G RG+ GPPG  G++G PG  G  G KG+ G
Sbjct: 815  GPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPG 863



 Score =  278 bits (712), Expect = 5e-74
 Identities = 162/365 (44%), Positives = 185/365 (50%), Gaps = 26/365 (7%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGV---NGTQGFQGCPG 2089
            P   +G+ G  G  G  GP G PGE G  G  G EG  G+ GPPG    +G  G +G PG
Sbjct: 822  PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG 881

Query: 2090 QRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERG 2149
            +RG+ G+ G PG KG  G  G  G  G  G++G  GS G  G PGR G +GP G  GE+G
Sbjct: 882  ERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKG 941

Query: 2150 DVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPG---GPGETGKNGGFGRRGPP 2206
              G +G  G  G+D  + GP G  G  GP GV G DG  G    PG+ G  G  G  GPP
Sbjct: 942  VPGEKGPIGPTGRDGVQ-GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPP 1000

Query: 2207 GAKGNKGGPGQPGFEGEQGTRGAQGPAGPAG------------PPGLIGEQGISGPRGSG 2254
            G  G  G  GQPG  G  G  GA+GP G  G            PPG IG QG+ GP G  
Sbjct: 1001 GPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEK 1060

Query: 2255 GAAG------APGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRR 2307
            G  G       PG  G  GP G  G  G  GP GG+GN GP GE G+ G  G  G +G  
Sbjct: 1061 GETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEP 1120

Query: 2308 GKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPK 2367
            G KG RG  G  G  G PGEPG  G  GP G  G +GN GP G  G  G PG  GP G  
Sbjct: 1121 GVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQD 1180

Query: 2368 GNRGD 2372
            G +GD
Sbjct: 1181 GAKGD 1185



 Score =  278 bits (710), Expect = 8e-74
 Identities = 161/357 (45%), Positives = 188/357 (52%), Gaps = 27/357 (7%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGV--- 2093
            SG++G RG  G  GP+G  G  G RG  G  G  G+ G  G +G  G  G PG+RG+   
Sbjct: 715  SGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGP 774

Query: 2094 KGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI 2153
            +G  GFPG KG  G  G DGL G  G +G  G  G+ G PG  G  GP+G  GE G +G 
Sbjct: 775  QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 834

Query: 2154 RGDPGNPGQDSQE-----RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208
            RG PG PG   ++      G +G  GD GP G PG+DG  G  G  G+ G  G  G PG 
Sbjct: 835  RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGL 894

Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2268
            KGN+G  G PG  G  G RGA G  GP GPPG  G Q   GP G+ G  G PGE+G  GP
Sbjct: 895  KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQ---GPPGAAGEKGVPGEKGPIGP 951

Query: 2269 LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGE 2327
             GR G  G  G  G  G  G  GE GD G  G  G +G +G KGE G PG PGP G  G+
Sbjct: 952  TGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQ 1011

Query: 2328 PGLNGTTGPKGIR------------GRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
            PG  G  G  G R            G RG +GPPG +G +   G PGP+G KG  GD
Sbjct: 1012 PGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ---GLPGPSGEKGETGD 1065



 Score =  272 bits (695), Expect = 4e-72
 Identities = 154/344 (44%), Positives = 188/344 (54%), Gaps = 30/344 (8%)

Query: 2043 RGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGE 2102
            RGP G +G  G PG  G  G PG +G  G+ GP G  G QG  G PG+ G +G  G  G 
Sbjct: 379  RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 438

Query: 2103 KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQ 2162
            +G  G+ G+ G  G DG  GLPG  G +G+ G +G  GP GE GERGD G          
Sbjct: 439  RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDG---------- 488

Query: 2163 DSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEG 2222
               E GP+G  G+ GP G+ G  G PG PG  G  G  G +GP G+ G +G PG PG +G
Sbjct: 489  ---EIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQG 545

Query: 2223 EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKG 2282
              GT+G  GP G  GP G  G QG  G  G  G+ G PG  G+ GP G KG  G  GP+G
Sbjct: 546  TPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQG 605

Query: 2283 GIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYP---------GPKGNPGEPGLNGT 2333
             +G  GPRG  G DG  G+  +G +G+KGE GFPG+          G  G PG  G +G 
Sbjct: 606  PLGYPGPRGVKGVDGIRGL--KGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGP 663

Query: 2334 TGPKGIRGRRGNSGPPGIVGQKGD------PGYPGPAGPKGNRG 2371
             GPKG  G  G+ GPPG++G+KG       PGYPG  GPKG+ G
Sbjct: 664  EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLG 707



 Score =  270 bits (690), Expect = 2e-71
 Identities = 157/393 (39%), Positives = 198/393 (50%), Gaps = 57/393 (14%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDG---YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094
            G  G  G  G  GP G PG+DG    RG+PG+ G PG  G PG+ G +G  G PG  G  
Sbjct: 851  GTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 910

Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI- 2153
            G RG  G  G +G        G  G +G PG++GEKG PG +G  GP G  G +G VG+ 
Sbjct: 911  GERGAAGSGGPIGP------PGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLP 964

Query: 2154 --------------RGDPGNPGQ-----DSQERGPKGETGDLGPMGVPGRDGVPGGPGET 2194
                          +G+ G+PGQ     +  E GP G  G +GP+G PG  G  G PG  
Sbjct: 965  GPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGAR 1024

Query: 2195 GKNGGFGRRGPPGAKGNKGGPGQPGFEG---EQGTRGAQGPAGPAGPPGLIGEQGISGPR 2251
            G  G FG +G  G +G  G PG  G +G     G +G  G  GP GPPG  G +G +GP 
Sbjct: 1025 GPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPN 1084

Query: 2252 GSGGAAGAPGERGRTGPLGRKGEPGE---PGPKGGIGNRGPRGETGDDGRDGV----GSE 2304
            G+ G  G PG  G  GP G KGEPGE   PG +G  G +GPRGE G+ G  G     G  
Sbjct: 1085 GADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1144

Query: 2305 GRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGN------------------S 2346
            G +G  G+ G  G PGP G PG+PG  G  GP+G  G +G+                  +
Sbjct: 1145 GPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGEN 1204

Query: 2347 GPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCAL 2379
            GPPG +G++G  G PG  G +G +G   D  A+
Sbjct: 1205 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAI 1237



 Score =  270 bits (689), Expect = 2e-71
 Identities = 164/375 (43%), Positives = 189/375 (50%), Gaps = 44/375 (11%)

Query: 2040 RGDRGPIGSIG---PKGIPGEDGYRGYPGDEGGPGERGPPGVNG------------TQGF 2084
            RG  GP+G  G   P G PG  G +G  GD G  G RGP G+ G              G 
Sbjct: 379  RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 438

Query: 2085 QGCPGQRGVKGSRGF------PGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGD 2138
            +G PG  GVKG RGF      PGEKG  G+ G  GL G  G+ G  G  GE G  G  G+
Sbjct: 439  RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 498

Query: 2139 KGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGG---PGETG 2195
             GPRG  G +G  GI G PG  G D  + GPKG  G  G  G PG+ G PG    PG  G
Sbjct: 499  SGPRGLLGPKGPPGIPGPPGVRGMDGPQ-GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQG 557

Query: 2196 KNGGFGRRGP------PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGP---------PG 2240
              G  G +GP      PG  G+ G PG PG EG  GT+G QGP+GP GP          G
Sbjct: 558  AIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKG 617

Query: 2241 LIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG 2300
            + G +G+ G +G  G  G PG +G  G  G +GE G PG +G  G  GP+G TG  G  G
Sbjct: 618  VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG 677

Query: 2301 V-GSEGRRGKKGERGFPGYP---GPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKG 2356
              G  G +GK G  G PGYP   GPKG+ G PG  G +G KG RG  G SGP G  G  G
Sbjct: 678  PPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTG 737

Query: 2357 DPGYPGPAGPKGNRG 2371
              G  GP G  G  G
Sbjct: 738  PRGQRGPRGATGKSG 752



 Score =  269 bits (688), Expect = 3e-71
 Identities = 162/381 (42%), Positives = 192/381 (50%), Gaps = 40/381 (10%)

Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGG------PGERGPPGV---NGT 2081
            G P    G+ G +GP G+ G KG+PGE G  G  G +G       PG  GPPGV   +G 
Sbjct: 919  GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGD 978

Query: 2082 QGFQGCPGQRGVKGSRGF------PGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGR 2135
            +G  G PGQ+G KG++G       PG  G VG+ G  G DGE G +G  G  G KG+ G 
Sbjct: 979  KGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGT 1038

Query: 2136 RGDKGP------------RGEKGERGDVGIRGDPGNPGQ-----DSQERGPKGETGDLGP 2178
            RG  GP             GEKGE GDVG  G PG PG       +   GP+G  G +G 
Sbjct: 1039 RGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN 1098

Query: 2179 MGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGP 2238
            +G PG  G PG  G  G  G  G +GP G +G KG  GQPG  G  G +G  G  GP G 
Sbjct: 1099 LGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN 1158

Query: 2239 PGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGG------IGNRGPRGE 2292
            PG +G  G  GP G GG  G  G +G  G  G  G+PG PGP G       +G RGP G 
Sbjct: 1159 PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1218

Query: 2293 TGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIV 2352
             G +GR G   +G +G  G  G PG  GP G  G  G  G  G +G+ G  G  G PG  
Sbjct: 1219 PGSEGRQG--GKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGAT 1276

Query: 2353 GQKGDPGYPGPAGPKGNRGDS 2373
            GQ G PG  GP G  G RGD+
Sbjct: 1277 GQAGPPGPVGPPGLPGLRGDA 1297



 Score =  266 bits (681), Expect = 2e-70
 Identities = 160/377 (42%), Positives = 195/377 (51%), Gaps = 50/377 (13%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G+ G+RG  G IGP+G+PGE G RG  G +G PG  GPPGV G  G QG  G  G +G  
Sbjct: 479  GEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEP 538

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157
            G PG++G  G  GL G  G  G  G  G  G+ G PG  G  GP G  G+ G  G +G+ 
Sbjct: 539  GPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQ 598

Query: 2158 GNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQ 2217
            G  G     +GP G  G  G  GV G  G+ G  GE G++G  G +G  G KG++G  G 
Sbjct: 599  GPSGP----QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV 654

Query: 2218 PGFEGE---QGTRGAQGPAGPAGPPGLIGEQGI------------SGPRGSGGAAGAPG- 2261
            PG  GE   +G +G  GP G  GPPGL+GE+G              GP+GS G  G PG 
Sbjct: 655  PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGA 714

Query: 2262 --ERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPG- 2317
              E+G  G  G+ G  GE GP G  G RGPRG TG  G  G  G +G  G  GERG PG 
Sbjct: 715  SGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGP 774

Query: 2318 -----YPGPKGN---------PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK-------- 2355
                 +PGPKG          PG PG  G     G +G+ G  GPPG+VG +        
Sbjct: 775  QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEV---GFQGKTGPPGPPGVVGPQGAAGETGP 831

Query: 2356 -GDPGYPGPAGPKGNRG 2371
             G+ G+PGP GP G +G
Sbjct: 832  MGERGHPGPPGPPGEQG 848



 Score =  263 bits (673), Expect = 2e-69
 Identities = 160/395 (40%), Positives = 195/395 (49%), Gaps = 57/395 (14%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQR- 2091
            P   +G+ G +G  G  GP G PGE G  G  G  G PG +GPPG  G  G  G PGQR 
Sbjct: 744  PRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRG 803

Query: 2092 --------------GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRG 2137
                          GV G +G  GE G +GE G  G  G  G++GLPG++G++G    +G
Sbjct: 804  EVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT---KG 860

Query: 2138 DKGPRGEKGERGDVGIRGDPGNPGQDSQERGP-----KGETGDLGPMGVPGRDGVPGGPG 2192
            D GP G  G+ G  G+RG PG  G      GP     +G +G  GP G PG  G  G  G
Sbjct: 861  DPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGG 920

Query: 2193 ETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPA---GPAGPPGLIGEQGISG 2249
              G  G  G +GPPGA G KG PG+ G  G  G  G QGP    GPAGPPG+ GE G  G
Sbjct: 921  PIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 980

Query: 2250 PRGSGGAAGAPGERGR------TGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG--- 2300
              G  G  G  G +G        GP+G  G+PG  G  G  G RGP+G  G  G +G   
Sbjct: 981  EVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRG 1040

Query: 2301 -------VGSEGRRGKKGERGFPGYPGPKGNPGEP------GLNGTTGPKGIRGRRGNSG 2347
                   +G +G  G  GE+G  G  GP G PG P      G NG  GP+G  G  GN G
Sbjct: 1041 FNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLG 1100

Query: 2348 PPGIVGQ---------KGDPGYPGPAGPKGNRGDS 2373
            PPG  G+         +G+PG  GP G +G +G+S
Sbjct: 1101 PPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGES 1135



 Score =  241 bits (616), Expect = 6e-63
 Identities = 148/362 (40%), Positives = 178/362 (49%), Gaps = 35/362 (9%)

Query: 2044 GPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK-------GS 2096
            GP G  GP G+ G  G +G PG  G PGERGPPG  G  G  G PG  G         GS
Sbjct: 292  GPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGS 351

Query: 2097 RGFPGEKGEV--------------GEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142
             G  G+KG V                + L G  G  G  G PG  G+ G+PG +G+ G  
Sbjct: 352  GG--GDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 409

Query: 2143 GEKGERGDVGIRGDPGNPGQDSQER--GPKGETGDLGPMGVPGRDGVPGGPGETGKNGGF 2200
            G +G RG  G+ G PG  G+  +    G +G  GD G  G  G DG+PG PGE G  G  
Sbjct: 410  GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDT 469

Query: 2201 GRRG---PPGAKGNKGGPGQ---PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSG 2254
            G +G   PPG  G +G  G+    G  GE G RG  GP GP G PG  G +G+ GP+G  
Sbjct: 470  GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPK 529

Query: 2255 GAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV----GSEGRRGKK 2310
            G+ G  GE G  G  G  G  G PGP+G IG  G +G  G  G  G+    G  G  GK+
Sbjct: 530  GSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKE 589

Query: 2311 GERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNR 2370
            G  G  G  GP G  G  G  G  G KG+ G RG  G  G  G+ G PG+ G  G KG+R
Sbjct: 590  GPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDR 649

Query: 2371 GD 2372
            G+
Sbjct: 650  GE 651



 Score =  223 bits (569), Expect = 2e-57
 Identities = 139/347 (40%), Positives = 172/347 (49%), Gaps = 43/347 (12%)

Query: 2050 GPKGIPGEDG----------YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGF 2099
            GP+G+ GE G            G PG EG  G  GPPG+ G  G  G PG+RG  G  G 
Sbjct: 270  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 329

Query: 2100 PGEKGEVGEIGLDGL-----DGEDGDKGLPGSSGEKG-----NPGRRGDKGPRGEKGERG 2149
            PG  G  G  G   +         GDKG   ++ E          R   +GP G  G  G
Sbjct: 330  PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTG 389

Query: 2150 DVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAK 2209
              G  G PG+PG        KGE+GDLGP G  G  G+ G PG+ G      RRG  GA 
Sbjct: 390  RPGPLGQPGSPGL-------KGESGDLGPQGPRGPQGLTGPPGKAG------RRGRAGAD 436

Query: 2210 GNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPL 2269
            G +G PG PG +G++G  G  G  G  G  G  G QG+ GP G  G      ERG  G +
Sbjct: 437  GARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDG------ERGDDGEI 490

Query: 2270 GRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGE- 2327
            G +G PGE GP+G +G +GP G  G  G  G+ G +G +G  G +G PG PG +G PG  
Sbjct: 491  GPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQ 550

Query: 2328 --PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
              PG  G  GP G +G +G  G PG+ G  G PG+PG  GP G +G+
Sbjct: 551  GLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN 597



 Score =  189 bits (479), Expect = 5e-47
 Identities = 114/263 (43%), Positives = 133/263 (50%), Gaps = 26/263 (9%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G+ G  G  G  GPKG  G+DG +G PG  G PG+ GPPG  G +G  G  G RG  G  
Sbjct: 1133 GESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEP 1192

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKG------------PRGEK 2145
            G PG  G  GE G  G  G+ G  G PGS G +G  G +GD G            P G  
Sbjct: 1193 GQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA 1252

Query: 2146 GERGDVGIRGDPGNPGQDSQE--RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRR 2203
            G+ G  G+RG PG+ GQ  +    G  G  G +GP G+PG  G  G  GE G  G  G  
Sbjct: 1253 GKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLI 1312

Query: 2204 GPPGAKGNKG-----GP-GQPGFEGEQGTRGAQGP---AGPAGPPGLIGEQGISGPRGSG 2254
            GPPG +G KG     GP G PG +GE G  GA GP    GP   PGL G  G  G +G+ 
Sbjct: 1313 GPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP---PGLPGPAGPKGAKGAT 1369

Query: 2255 GAAGAPGERGRTGPLGRKGEPGE 2277
            G  G  GE+G  GP G  G PGE
Sbjct: 1370 GPGGPKGEKGVQGPPGHPGPPGE 1392



 Score =  171 bits (432), Expect = 1e-41
 Identities = 101/228 (44%), Positives = 118/228 (51%), Gaps = 10/228 (4%)

Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQ 2090
            G P    G +GDRG  G  G  G PG  G  G PG     G+RGP G  G++G QG  G 
Sbjct: 1174 GGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP---LGKRGPAGSPGSEGRQGGKGA 1230

Query: 2091 RGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD 2150
            +G  G+ G PG+ G VG  G  G  G DG +GLPGS G++G PG  G  GP G  G  G 
Sbjct: 1231 KGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGL 1290

Query: 2151 VGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKG 2210
             G+RGD G  G    E+G  G  G +GP G  G  G  G PG  G  G  G  G PGA G
Sbjct: 1291 PGLRGDAGAKG----EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASG 1346

Query: 2211 NKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAG 2258
              G  G PG  G  G +GA+G  GP GP    GE+G+ GP G  G  G
Sbjct: 1347 PIGPGGPPGLPGPAGPKGAKGATGPGGPK---GEKGVQGPPGHPGPPG 1391



 Score =  149 bits (375), Expect = 6e-35
 Identities = 98/248 (39%), Positives = 123/248 (49%), Gaps = 18/248 (7%)

Query: 2133 PGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPG 2192
            P  +   GPRG KGE+G+  +  +PG         GP G  G  G +G PG  G PG  G
Sbjct: 263  PQSQAAHGPRGLKGEKGEPAVL-EPG-----MLVEGPPGPEGPAGLIGPPGIQGNPGPVG 316

Query: 2193 ETGKNGGFGRRGPPGAKGNKGGPGQP-----GFEGEQGTRGAQGPAGPAGPPGLIGEQGI 2247
            + G+ G  GR G PG+ G  G PG        F    G +G    A  A    ++ +  +
Sbjct: 317  DPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARL 376

Query: 2248 S--GPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEG 2305
            +  GP G  G  G PG  G+ G  G KGE G+ GP+G    RGP+G TG  G+   G  G
Sbjct: 377  ALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGP---RGPQGLTGPPGK--AGRRG 431

Query: 2306 RRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAG 2365
            R G  G RG PG PG KG+ G  GL G  G KG RG  G  G PG  G+ G+ G  G  G
Sbjct: 432  RAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIG 491

Query: 2366 PKGNRGDS 2373
            P+G  G+S
Sbjct: 492  PRGLPGES 499



 Score =  108 bits (271), Expect = 6e-23
 Identities = 67/164 (40%), Positives = 80/164 (48%), Gaps = 9/164 (5%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGT---QGFQGCPGQRGVK 2094
            GQ+G  G  G  GP G  G  G  G  GD G  GE+G PG+ G     G QG  G RG+ 
Sbjct: 1268 GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1327

Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154
            G +G PG+KGE+G  G  G  G  G  GLPG +G KG  G  G  GP+GEKG +G  G  
Sbjct: 1328 GPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHP 1387

Query: 2155 GDPGNPGQDSQERGPKGETGDLGPMGVPGRD------GVPGGPG 2192
            G PG   Q    + PK     +    +   D      G PG PG
Sbjct: 1388 GPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1431



 Score = 54.3 bits (129), Expect = 2e-06
 Identities = 32/76 (42%), Positives = 37/76 (48%), Gaps = 4/76 (5%)

Query: 2303 SEGRRGKKGERGFPGYPGP----KGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDP 2358
            + G RG KGE+G P    P    +G PG  G  G  GP GI+G  G  G PG  G  G  
Sbjct: 268  AHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA 327

Query: 2359 GYPGPAGPKGNRGDSI 2374
            G PG  G  G  G S+
Sbjct: 328  GLPGSDGAPGPPGTSL 343



 Score = 39.3 bits (90), Expect = 0.063
 Identities = 41/124 (33%), Positives = 48/124 (38%), Gaps = 31/124 (25%)

Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQ 2090
            G P    G  G +G  G+ GP G  GE G +G PG  G PGE            Q  P Q
Sbjct: 1351 GGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGE----------VIQPLPIQ 1400

Query: 2091 ------RGVKGSR-----------GFPGEKGEVGEI--GLDGLDGEDGDKGLPGSSGEKG 2131
                  R V GSR           G PG  G + EI   LD L  E      P  +G + 
Sbjct: 1401 MPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRP--TGTQD 1458

Query: 2132 NPGR 2135
            +P R
Sbjct: 1459 SPAR 1462


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score =  282 bits (721), Expect = 4e-75
 Identities = 166/361 (45%), Positives = 191/361 (52%), Gaps = 39/361 (10%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGD------EGGPGERGPPGVNGTQGFQGCPGQR 2091
            G RG  GP G IG +G+PG  G +G  GD       G PG RGP G NG  G QG PG  
Sbjct: 1144 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG-- 1201

Query: 2092 GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD- 2150
            GV G+ G PGEKGE GE G  G+ GE G KG  G  GEKG  G+ G+ GP G KG  GD 
Sbjct: 1202 GV-GNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD 1260

Query: 2151 --------VGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGR 2202
                    VG  GDPG PG+    RG  G  GD G  G PG+ G PG  GE G  G  G+
Sbjct: 1261 GPKGNPGPVGFPGDPGPPGEGGP-RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGK 1319

Query: 2203 RGP---PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGA 2259
            RGP   PG++G +GG G  G  G  G  G  GP GPAGP G  G  G+ G  GS G  G 
Sbjct: 1320 RGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGR 1379

Query: 2260 PGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYP 2319
            PG  G+ GP G  G PG PG +G  G +G +G  G  G   +G  G +G+KG+RG PG  
Sbjct: 1380 PGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL--IGPPGEQGEKGDRGLPGPQ 1437

Query: 2320 GPKGNPGE---------------PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPA 2364
            G  G  GE               PGL G  GPKG +G  G  GP G  G +G PG+PGP 
Sbjct: 1438 GSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPP 1497

Query: 2365 G 2365
            G
Sbjct: 1498 G 1498



 Score =  281 bits (719), Expect = 7e-75
 Identities = 160/348 (45%), Positives = 190/348 (54%), Gaps = 17/348 (4%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G+ G  GP G IGP G PG  G  G PG  G  G  G  G  GT+GF G PG  G++G  
Sbjct: 1102 GEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLP 1161

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPG---SSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154
            G  GEKGE G++G  G  G  G +G  G   + G +G PG  G+ GP GEKGE G+ G  
Sbjct: 1162 GPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSP 1221

Query: 2155 GDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGG 2214
            G  G PG     +GP+GE G+ G  G PG  G PG  G TG +G  G  GP G  G+ G 
Sbjct: 1222 GIQGEPGV----KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGP 1277

Query: 2215 PGQPGFEGEQGT---RGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGR 2271
            PG+ G  G+ G    RG  G  G  G PG  GE G  GP G  G AG+PG  GR G  G 
Sbjct: 1278 PGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGA 1337

Query: 2272 KGEPGE---PGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGE 2327
            KG+PG    PG  G +G  GP G+ G DG  G+ GS G++G+ G  G  G PGP G PG 
Sbjct: 1338 KGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGL 1397

Query: 2328 PGLNGTTGPKGIRGRRGNSG---PPGIVGQKGDPGYPGPAGPKGNRGD 2372
            PGL G  G KG +G  G  G   PPG  G+KGD G PGP G  G +G+
Sbjct: 1398 PGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGE 1445



 Score =  281 bits (718), Expect = 9e-75
 Identities = 173/398 (43%), Positives = 198/398 (49%), Gaps = 65/398 (16%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERG---------------PPGVNGTQ 2082
            G  G++GP G  G  G+PG DG  G+PG EG PG +G               P GV G  
Sbjct: 667  GPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVD 726

Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVG------EIGLDGLDGEDG------------DKGLP 2124
            G +G  G +G KG  GFPG KG++G      E+G+ G  GEDG            D G P
Sbjct: 727  GIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPP 786

Query: 2125 GSSGEKGN---------PGRRGDKGP---------RGEKGER---GDVGIRGDPGNPGQD 2163
            G  GEKG          PGR+G KG           GEKG R   G  G RG+ G  G  
Sbjct: 787  GLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPR 846

Query: 2164 SQERGPKGETGDLGPMGVPGRDGVPGGPGE------TGKNGGFGRRGPPGAKGNKGGPGQ 2217
             Q RGP+G TG  G  G  G DG  G PGE       G NG  G +GPPG  G  G PG 
Sbjct: 847  GQ-RGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGH 905

Query: 2218 PGFEGEQGTRGAQGPAGP---AGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGE 2274
            PG  GE G +G  GP GP    GP G  GE G  G RG  G  G PGE+G  G  G++G 
Sbjct: 906  PGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 965

Query: 2275 PGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGLNGT 2333
             G+PGP G  G  GP G  G  G  G+ G+ G  G KG  G  G PGP G+PGE G  G+
Sbjct: 966  KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 1025

Query: 2334 TGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
             GP G  GR G  GPPG  G+KG PG  GP GP G  G
Sbjct: 1026 GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDG 1063



 Score =  279 bits (714), Expect = 3e-74
 Identities = 161/349 (46%), Positives = 193/349 (55%), Gaps = 21/349 (6%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERG---PPGVNGTQGFQGCPGQRGVK 2094
            G  G +GP GS+GP+G PG  G +G PG +G PG +G   P G  G QG  G PG  G  
Sbjct: 628  GMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSD 687

Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGE------R 2148
            G  G PG++G  G  G  G  G  G  G PG  G KG  G RG KG +GEKGE      +
Sbjct: 688  GPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFK 747

Query: 2149 GDVGIRGD------PGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGR 2202
            GD+G++GD      PG+ G+D  E GPKG TG  G  G PG  G  G  G  G  G  GR
Sbjct: 748  GDIGVKGDRGEVGVPGSRGEDGPE-GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR 806

Query: 2203 RGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE 2262
            +GP   KG+ G PG PG  GE+G RG  G +GP G  G  G +G  GPRG+ G +GA G 
Sbjct: 807  QGP---KGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGT 863

Query: 2263 RGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPK 2322
             G  GP G  GE G PGP+G  G  GP+G  G  G+DG+   G  G++GE GF G  GP 
Sbjct: 864  SGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL--PGHPGQRGEVGFQGKTGPP 921

Query: 2323 GNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
            G PG  G  G  G  G  G RG+ GPPG  G++G PG  G  G KG+ G
Sbjct: 922  GPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPG 970



 Score =  278 bits (712), Expect = 5e-74
 Identities = 162/365 (44%), Positives = 185/365 (50%), Gaps = 26/365 (7%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGV---NGTQGFQGCPG 2089
            P   +G+ G  G  G  GP G PGE G  G  G EG  G+ GPPG    +G  G +G PG
Sbjct: 929  PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG 988

Query: 2090 QRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERG 2149
            +RG+ G+ G PG KG  G  G  G  G  G++G  GS G  G PGR G +GP G  GE+G
Sbjct: 989  ERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKG 1048

Query: 2150 DVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPG---GPGETGKNGGFGRRGPP 2206
              G +G  G  G+D  + GP G  G  GP GV G DG  G    PG+ G  G  G  GPP
Sbjct: 1049 VPGEKGPIGPTGRDGVQ-GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPP 1107

Query: 2207 GAKGNKGGPGQPGFEGEQGTRGAQGPAGPAG------------PPGLIGEQGISGPRGSG 2254
            G  G  G  GQPG  G  G  GA+GP G  G            PPG IG QG+ GP G  
Sbjct: 1108 GPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEK 1167

Query: 2255 GAAG------APGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRR 2307
            G  G       PG  G  GP G  G  G  GP GG+GN GP GE G+ G  G  G +G  
Sbjct: 1168 GETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEP 1227

Query: 2308 GKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPK 2367
            G KG RG  G  G  G PGEPG  G  GP G  G +GN GP G  G  G PG  GP G  
Sbjct: 1228 GVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQD 1287

Query: 2368 GNRGD 2372
            G +GD
Sbjct: 1288 GAKGD 1292



 Score =  278 bits (710), Expect = 8e-74
 Identities = 161/357 (45%), Positives = 188/357 (52%), Gaps = 27/357 (7%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGV--- 2093
            SG++G RG  G  GP+G  G  G RG  G  G  G+ G  G +G  G  G PG+RG+   
Sbjct: 822  SGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGP 881

Query: 2094 KGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI 2153
            +G  GFPG KG  G  G DGL G  G +G  G  G+ G PG  G  GP+G  GE G +G 
Sbjct: 882  QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 941

Query: 2154 RGDPGNPGQDSQE-----RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208
            RG PG PG   ++      G +G  GD GP G PG+DG  G  G  G+ G  G  G PG 
Sbjct: 942  RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGL 1001

Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2268
            KGN+G  G PG  G  G RGA G  GP GPPG  G Q   GP G+ G  G PGE+G  GP
Sbjct: 1002 KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQ---GPPGAAGEKGVPGEKGPIGP 1058

Query: 2269 LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGE 2327
             GR G  G  G  G  G  G  GE GD G  G  G +G +G KGE G PG PGP G  G+
Sbjct: 1059 TGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQ 1118

Query: 2328 PGLNGTTGPKGIR------------GRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
            PG  G  G  G R            G RG +GPPG +G +   G PGP+G KG  GD
Sbjct: 1119 PGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ---GLPGPSGEKGETGD 1172



 Score =  272 bits (695), Expect = 4e-72
 Identities = 154/344 (44%), Positives = 188/344 (54%), Gaps = 30/344 (8%)

Query: 2043 RGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGE 2102
            RGP G +G  G PG  G  G PG +G  G+ GP G  G QG  G PG+ G +G  G  G 
Sbjct: 486  RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 545

Query: 2103 KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQ 2162
            +G  G+ G+ G  G DG  GLPG  G +G+ G +G  GP GE GERGD G          
Sbjct: 546  RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDG---------- 595

Query: 2163 DSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEG 2222
               E GP+G  G+ GP G+ G  G PG PG  G  G  G +GP G+ G +G PG PG +G
Sbjct: 596  ---EIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQG 652

Query: 2223 EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKG 2282
              GT+G  GP G  GP G  G QG  G  G  G+ G PG  G+ GP G KG  G  GP+G
Sbjct: 653  TPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQG 712

Query: 2283 GIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYP---------GPKGNPGEPGLNGT 2333
             +G  GPRG  G DG  G+  +G +G+KGE GFPG+          G  G PG  G +G 
Sbjct: 713  PLGYPGPRGVKGVDGIRGL--KGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGP 770

Query: 2334 TGPKGIRGRRGNSGPPGIVGQKGD------PGYPGPAGPKGNRG 2371
             GPKG  G  G+ GPPG++G+KG       PGYPG  GPKG+ G
Sbjct: 771  EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLG 814



 Score =  270 bits (690), Expect = 2e-71
 Identities = 157/393 (39%), Positives = 198/393 (50%), Gaps = 57/393 (14%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDG---YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094
            G  G  G  G  GP G PG+DG    RG+PG+ G PG  G PG+ G +G  G PG  G  
Sbjct: 958  GTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 1017

Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGI- 2153
            G RG  G  G +G        G  G +G PG++GEKG PG +G  GP G  G +G VG+ 
Sbjct: 1018 GERGAAGSGGPIGP------PGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLP 1071

Query: 2154 --------------RGDPGNPGQ-----DSQERGPKGETGDLGPMGVPGRDGVPGGPGET 2194
                          +G+ G+PGQ     +  E GP G  G +GP+G PG  G  G PG  
Sbjct: 1072 GPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGAR 1131

Query: 2195 GKNGGFGRRGPPGAKGNKGGPGQPGFEG---EQGTRGAQGPAGPAGPPGLIGEQGISGPR 2251
            G  G FG +G  G +G  G PG  G +G     G +G  G  GP GPPG  G +G +GP 
Sbjct: 1132 GPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPN 1191

Query: 2252 GSGGAAGAPGERGRTGPLGRKGEPGE---PGPKGGIGNRGPRGETGDDGRDGV----GSE 2304
            G+ G  G PG  G  GP G KGEPGE   PG +G  G +GPRGE G+ G  G     G  
Sbjct: 1192 GADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1251

Query: 2305 GRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGN------------------S 2346
            G +G  G+ G  G PGP G PG+PG  G  GP+G  G +G+                  +
Sbjct: 1252 GPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGEN 1311

Query: 2347 GPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCAL 2379
            GPPG +G++G  G PG  G +G +G   D  A+
Sbjct: 1312 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAI 1344



 Score =  270 bits (689), Expect = 2e-71
 Identities = 164/375 (43%), Positives = 189/375 (50%), Gaps = 44/375 (11%)

Query: 2040 RGDRGPIGSIG---PKGIPGEDGYRGYPGDEGGPGERGPPGVNG------------TQGF 2084
            RG  GP+G  G   P G PG  G +G  GD G  G RGP G+ G              G 
Sbjct: 486  RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 545

Query: 2085 QGCPGQRGVKGSRGF------PGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGD 2138
            +G PG  GVKG RGF      PGEKG  G+ G  GL G  G+ G  G  GE G  G  G+
Sbjct: 546  RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 605

Query: 2139 KGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGG---PGETG 2195
             GPRG  G +G  GI G PG  G D  + GPKG  G  G  G PG+ G PG    PG  G
Sbjct: 606  SGPRGLLGPKGPPGIPGPPGVRGMDGPQ-GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQG 664

Query: 2196 KNGGFGRRGP------PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGP---------PG 2240
              G  G +GP      PG  G+ G PG PG EG  GT+G QGP+GP GP          G
Sbjct: 665  AIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKG 724

Query: 2241 LIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG 2300
            + G +G+ G +G  G  G PG +G  G  G +GE G PG +G  G  GP+G TG  G  G
Sbjct: 725  VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG 784

Query: 2301 V-GSEGRRGKKGERGFPGYP---GPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKG 2356
              G  G +GK G  G PGYP   GPKG+ G PG  G +G KG RG  G SGP G  G  G
Sbjct: 785  PPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTG 844

Query: 2357 DPGYPGPAGPKGNRG 2371
              G  GP G  G  G
Sbjct: 845  PRGQRGPRGATGKSG 859



 Score =  269 bits (688), Expect = 3e-71
 Identities = 162/381 (42%), Positives = 192/381 (50%), Gaps = 40/381 (10%)

Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGG------PGERGPPGV---NGT 2081
            G P    G+ G +GP G+ G KG+PGE G  G  G +G       PG  GPPGV   +G 
Sbjct: 1026 GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGD 1085

Query: 2082 QGFQGCPGQRGVKGSRGF------PGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGR 2135
            +G  G PGQ+G KG++G       PG  G VG+ G  G DGE G +G  G  G KG+ G 
Sbjct: 1086 KGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGT 1145

Query: 2136 RGDKGP------------RGEKGERGDVGIRGDPGNPGQ-----DSQERGPKGETGDLGP 2178
            RG  GP             GEKGE GDVG  G PG PG       +   GP+G  G +G 
Sbjct: 1146 RGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN 1205

Query: 2179 MGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGP 2238
            +G PG  G PG  G  G  G  G +GP G +G KG  GQPG  G  G +G  G  GP G 
Sbjct: 1206 LGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN 1265

Query: 2239 PGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGG------IGNRGPRGE 2292
            PG +G  G  GP G GG  G  G +G  G  G  G+PG PGP G       +G RGP G 
Sbjct: 1266 PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1325

Query: 2293 TGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIV 2352
             G +GR G   +G +G  G  G PG  GP G  G  G  G  G +G+ G  G  G PG  
Sbjct: 1326 PGSEGRQG--GKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGAT 1383

Query: 2353 GQKGDPGYPGPAGPKGNRGDS 2373
            GQ G PG  GP G  G RGD+
Sbjct: 1384 GQAGPPGPVGPPGLPGLRGDA 1404



 Score =  266 bits (681), Expect = 2e-70
 Identities = 160/377 (42%), Positives = 195/377 (51%), Gaps = 50/377 (13%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G+ G+RG  G IGP+G+PGE G RG  G +G PG  GPPGV G  G QG  G  G +G  
Sbjct: 586  GEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEP 645

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDP 2157
            G PG++G  G  GL G  G  G  G  G  G+ G PG  G  GP G  G+ G  G +G+ 
Sbjct: 646  GPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQ 705

Query: 2158 GNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQ 2217
            G  G     +GP G  G  G  GV G  G+ G  GE G++G  G +G  G KG++G  G 
Sbjct: 706  GPSGP----QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV 761

Query: 2218 PGFEGE---QGTRGAQGPAGPAGPPGLIGEQGI------------SGPRGSGGAAGAPG- 2261
            PG  GE   +G +G  GP G  GPPGL+GE+G              GP+GS G  G PG 
Sbjct: 762  PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGA 821

Query: 2262 --ERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPG- 2317
              E+G  G  G+ G  GE GP G  G RGPRG TG  G  G  G +G  G  GERG PG 
Sbjct: 822  SGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGP 881

Query: 2318 -----YPGPKGN---------PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK-------- 2355
                 +PGPKG          PG PG  G     G +G+ G  GPPG+VG +        
Sbjct: 882  QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEV---GFQGKTGPPGPPGVVGPQGAAGETGP 938

Query: 2356 -GDPGYPGPAGPKGNRG 2371
             G+ G+PGP GP G +G
Sbjct: 939  MGERGHPGPPGPPGEQG 955



 Score =  263 bits (673), Expect = 2e-69
 Identities = 160/395 (40%), Positives = 195/395 (49%), Gaps = 57/395 (14%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQR- 2091
            P   +G+ G +G  G  GP G PGE G  G  G  G PG +GPPG  G  G  G PGQR 
Sbjct: 851  PRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRG 910

Query: 2092 --------------GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRG 2137
                          GV G +G  GE G +GE G  G  G  G++GLPG++G++G    +G
Sbjct: 911  EVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT---KG 967

Query: 2138 DKGPRGEKGERGDVGIRGDPGNPGQDSQERGP-----KGETGDLGPMGVPGRDGVPGGPG 2192
            D GP G  G+ G  G+RG PG  G      GP     +G +G  GP G PG  G  G  G
Sbjct: 968  DPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGG 1027

Query: 2193 ETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPA---GPAGPPGLIGEQGISG 2249
              G  G  G +GPPGA G KG PG+ G  G  G  G QGP    GPAGPPG+ GE G  G
Sbjct: 1028 PIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 1087

Query: 2250 PRGSGGAAGAPGERGR------TGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG--- 2300
              G  G  G  G +G        GP+G  G+PG  G  G  G RGP+G  G  G +G   
Sbjct: 1088 EVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRG 1147

Query: 2301 -------VGSEGRRGKKGERGFPGYPGPKGNPGEP------GLNGTTGPKGIRGRRGNSG 2347
                   +G +G  G  GE+G  G  GP G PG P      G NG  GP+G  G  GN G
Sbjct: 1148 FNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLG 1207

Query: 2348 PPGIVGQ---------KGDPGYPGPAGPKGNRGDS 2373
            PPG  G+         +G+PG  GP G +G +G+S
Sbjct: 1208 PPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGES 1242



 Score =  241 bits (616), Expect = 6e-63
 Identities = 148/362 (40%), Positives = 178/362 (49%), Gaps = 35/362 (9%)

Query: 2044 GPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK-------GS 2096
            GP G  GP G+ G  G +G PG  G PGERGPPG  G  G  G PG  G         GS
Sbjct: 399  GPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGS 458

Query: 2097 RGFPGEKGEV--------------GEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPR 2142
             G  G+KG V                + L G  G  G  G PG  G+ G+PG +G+ G  
Sbjct: 459  GG--GDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 516

Query: 2143 GEKGERGDVGIRGDPGNPGQDSQER--GPKGETGDLGPMGVPGRDGVPGGPGETGKNGGF 2200
            G +G RG  G+ G PG  G+  +    G +G  GD G  G  G DG+PG PGE G  G  
Sbjct: 517  GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDT 576

Query: 2201 GRRG---PPGAKGNKGGPGQ---PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSG 2254
            G +G   PPG  G +G  G+    G  GE G RG  GP GP G PG  G +G+ GP+G  
Sbjct: 577  GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPK 636

Query: 2255 GAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV----GSEGRRGKK 2310
            G+ G  GE G  G  G  G  G PGP+G IG  G +G  G  G  G+    G  G  GK+
Sbjct: 637  GSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKE 696

Query: 2311 GERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNR 2370
            G  G  G  GP G  G  G  G  G KG+ G RG  G  G  G+ G PG+ G  G KG+R
Sbjct: 697  GPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDR 756

Query: 2371 GD 2372
            G+
Sbjct: 757  GE 758



 Score =  223 bits (569), Expect = 2e-57
 Identities = 139/347 (40%), Positives = 172/347 (49%), Gaps = 43/347 (12%)

Query: 2050 GPKGIPGEDG----------YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGF 2099
            GP+G+ GE G            G PG EG  G  GPPG+ G  G  G PG+RG  G  G 
Sbjct: 377  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 436

Query: 2100 PGEKGEVGEIGLDGL-----DGEDGDKGLPGSSGEKG-----NPGRRGDKGPRGEKGERG 2149
            PG  G  G  G   +         GDKG   ++ E          R   +GP G  G  G
Sbjct: 437  PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTG 496

Query: 2150 DVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAK 2209
              G  G PG+PG        KGE+GDLGP G  G  G+ G PG+ G      RRG  GA 
Sbjct: 497  RPGPLGQPGSPGL-------KGESGDLGPQGPRGPQGLTGPPGKAG------RRGRAGAD 543

Query: 2210 GNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPL 2269
            G +G PG PG +G++G  G  G  G  G  G  G QG+ GP G  G      ERG  G +
Sbjct: 544  GARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDG------ERGDDGEI 597

Query: 2270 GRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGE- 2327
            G +G PGE GP+G +G +GP G  G  G  G+ G +G +G  G +G PG PG +G PG  
Sbjct: 598  GPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQ 657

Query: 2328 --PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
              PG  G  GP G +G +G  G PG+ G  G PG+PG  GP G +G+
Sbjct: 658  GLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN 704



 Score =  189 bits (479), Expect = 5e-47
 Identities = 114/263 (43%), Positives = 133/263 (50%), Gaps = 26/263 (9%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G+ G  G  G  GPKG  G+DG +G PG  G PG+ GPPG  G +G  G  G RG  G  
Sbjct: 1240 GESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEP 1299

Query: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKG------------PRGEK 2145
            G PG  G  GE G  G  G+ G  G PGS G +G  G +GD G            P G  
Sbjct: 1300 GQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA 1359

Query: 2146 GERGDVGIRGDPGNPGQDSQE--RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRR 2203
            G+ G  G+RG PG+ GQ  +    G  G  G +GP G+PG  G  G  GE G  G  G  
Sbjct: 1360 GKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLI 1419

Query: 2204 GPPGAKGNKG-----GP-GQPGFEGEQGTRGAQGP---AGPAGPPGLIGEQGISGPRGSG 2254
            GPPG +G KG     GP G PG +GE G  GA GP    GP   PGL G  G  G +G+ 
Sbjct: 1420 GPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP---PGLPGPAGPKGAKGAT 1476

Query: 2255 GAAGAPGERGRTGPLGRKGEPGE 2277
            G  G  GE+G  GP G  G PGE
Sbjct: 1477 GPGGPKGEKGVQGPPGHPGPPGE 1499



 Score =  171 bits (432), Expect = 1e-41
 Identities = 101/228 (44%), Positives = 118/228 (51%), Gaps = 10/228 (4%)

Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQ 2090
            G P    G +GDRG  G  G  G PG  G  G PG     G+RGP G  G++G QG  G 
Sbjct: 1281 GGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP---LGKRGPAGSPGSEGRQGGKGA 1337

Query: 2091 RGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD 2150
            +G  G+ G PG+ G VG  G  G  G DG +GLPGS G++G PG  G  GP G  G  G 
Sbjct: 1338 KGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGL 1397

Query: 2151 VGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKG 2210
             G+RGD G  G    E+G  G  G +GP G  G  G  G PG  G  G  G  G PGA G
Sbjct: 1398 PGLRGDAGAKG----EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASG 1453

Query: 2211 NKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAG 2258
              G  G PG  G  G +GA+G  GP GP    GE+G+ GP G  G  G
Sbjct: 1454 PIGPGGPPGLPGPAGPKGAKGATGPGGPK---GEKGVQGPPGHPGPPG 1498



 Score =  149 bits (377), Expect = 3e-35
 Identities = 101/257 (39%), Positives = 126/257 (49%), Gaps = 19/257 (7%)

Query: 2124 PGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPG 2183
            P  S E  + G     GPRG KGE+G+  +  +PG         GP G  G  G +G PG
Sbjct: 362  PALSAETAHSGAAAH-GPRGLKGEKGEPAVL-EPG-----MLVEGPPGPEGPAGLIGPPG 414

Query: 2184 RDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQP-----GFEGEQGTRGAQGPAGPAGP 2238
              G PG  G+ G+ G  GR G PG+ G  G PG        F    G +G    A  A  
Sbjct: 415  IQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQA 474

Query: 2239 PGLIGEQGIS--GPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDD 2296
              ++ +  ++  GP G  G  G PG  G+ G  G KGE G+ GP+G    RGP+G TG  
Sbjct: 475  QAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGP---RGPQGLTGPP 531

Query: 2297 GRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKG 2356
            G+   G  GR G  G RG PG PG KG+ G  GL G  G KG RG  G  G PG  G+ G
Sbjct: 532  GK--AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDG 589

Query: 2357 DPGYPGPAGPKGNRGDS 2373
            + G  G  GP+G  G+S
Sbjct: 590  ERGDDGEIGPRGLPGES 606



 Score =  108 bits (271), Expect = 6e-23
 Identities = 67/164 (40%), Positives = 80/164 (48%), Gaps = 9/164 (5%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGT---QGFQGCPGQRGVK 2094
            GQ+G  G  G  GP G  G  G  G  GD G  GE+G PG+ G     G QG  G RG+ 
Sbjct: 1375 GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1434

Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154
            G +G PG+KGE+G  G  G  G  G  GLPG +G KG  G  G  GP+GEKG +G  G  
Sbjct: 1435 GPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHP 1494

Query: 2155 GDPGNPGQDSQERGPKGETGDLGPMGVPGRD------GVPGGPG 2192
            G PG   Q    + PK     +    +   D      G PG PG
Sbjct: 1495 GPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1538



 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 33/86 (38%), Positives = 40/86 (46%), Gaps = 4/86 (4%)

Query: 2293 TGDDGRDGVGSEGRRGKKGERGFPGYPGP----KGNPGEPGLNGTTGPKGIRGRRGNSGP 2348
            + +    G  + G RG KGE+G P    P    +G PG  G  G  GP GI+G  G  G 
Sbjct: 365  SAETAHSGAAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGD 424

Query: 2349 PGIVGQKGDPGYPGPAGPKGNRGDSI 2374
            PG  G  G  G PG  G  G  G S+
Sbjct: 425  PGERGPPGRAGLPGSDGAPGPPGTSL 450



 Score = 39.3 bits (90), Expect = 0.063
 Identities = 41/124 (33%), Positives = 48/124 (38%), Gaps = 31/124 (25%)

Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQ 2090
            G P    G  G +G  G+ GP G  GE G +G PG  G PGE            Q  P Q
Sbjct: 1458 GGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGE----------VIQPLPIQ 1507

Query: 2091 ------RGVKGSR-----------GFPGEKGEVGEI--GLDGLDGEDGDKGLPGSSGEKG 2131
                  R V GSR           G PG  G + EI   LD L  E      P  +G + 
Sbjct: 1508 MPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRP--TGTQD 1565

Query: 2132 NPGR 2135
            +P R
Sbjct: 1566 SPAR 1569


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score =  280 bits (715), Expect = 2e-74
 Identities = 167/412 (40%), Positives = 196/412 (47%), Gaps = 77/412 (18%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096
            SG  G  GPIGS GP G PG DG +G PG  G  G  GP G +G  G +G  G  G KG 
Sbjct: 597  SGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGE 656

Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGDKGLP------------------GSSGEKGNPGRRGD 2138
            +G PG +GE+G  G DG  G  G  G P                  G +G +G+PG RG+
Sbjct: 657  KGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGE 716

Query: 2139 KGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVP---------- 2188
             GP G  G  G  G  G PG  G+    +GPKGE G +GP G  G  G            
Sbjct: 717  VGPAGPNGFAGPAGAAGQPGAKGERG-AKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAG 775

Query: 2189 -----GGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGP-------- 2235
                 G PG TG  G  GR GPPG  G  G PG PG  G++G RG +G  GP        
Sbjct: 776  SRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVG 835

Query: 2236 -AGPPGLIGEQGISGPRGSGGAAGAPGER---------------------------GRTG 2267
              GPPG  GE+G SG  G+ G  G PG +                           G  G
Sbjct: 836  AVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPG 895

Query: 2268 PLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-------VGSEGRRGKKGERGFPGYPG 2320
            PLG  G PG  GP G +G+ G  G  G+ GRDG        G +G+ G KGERG+PG  G
Sbjct: 896  PLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIG 955

Query: 2321 PKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
            P G  G PG +G  GP G  G RG +GP G VG  G  G  GP+GP+G RGD
Sbjct: 956  PVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGD 1007



 Score =  269 bits (688), Expect = 3e-71
 Identities = 159/364 (43%), Positives = 187/364 (51%), Gaps = 29/364 (7%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPG---EDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPG 2089
            P    G+ G++G  GS GP+G PG   E+G RG  G+ G  G  GPPG+ G+ G +G PG
Sbjct: 350  PAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPG 409

Query: 2090 QRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERG 2149
              G  G  G PG +G  G  G+ G +G+ G  G PG  G +G PG  G+ GP G++G  G
Sbjct: 410  ADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVG 469

Query: 2150 DVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAK 2209
              GI G PG  G      G +GE G++G  G  G  G PG  G+ G  G  G RG PG  
Sbjct: 470  LPGIDGRPGPIGP----AGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPD 525

Query: 2210 GNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPL 2269
            GN G  G PG +G QG +G QGP GP G  GL G  G +G  G  G  G  GE G  GP 
Sbjct: 526  GNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPA 585

Query: 2270 GRKGEPGEP------GPKGGIGNRGPRGETGDDGRDG----------VGSEGRRGKKGER 2313
            G +GE G P      GP G IG+RGP G  G DG  G           G  G  G  GER
Sbjct: 586  GPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGER 645

Query: 2314 GFPGYPGPKGNPGEPGLNGTTGPKGIRGRR------GNSGPPGIVGQKGDPGYPGPAGPK 2367
            G  G PG KG  GEPGL G  G  G  G R      G  GP G  G +G+ G  GPAGP 
Sbjct: 646  GAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPA 705

Query: 2368 GNRG 2371
            G RG
Sbjct: 706  GPRG 709



 Score =  269 bits (688), Expect = 3e-71
 Identities = 160/357 (44%), Positives = 185/357 (51%), Gaps = 30/357 (8%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGD------EGGPGERGPPGVNGTQGFQGCPGQR 2091
            G+ GD+G  G  G +G PG DG  G  G       +GG GE+GPPG     GFQG PG  
Sbjct: 505  GKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPG---PPGFQGLPGPS 561

Query: 2092 GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPG---RRGDKGPRGEKGER 2148
            G  G  G PGE+G  GE GL G  G  G++G PG SG  G  G    RG  GP G  G +
Sbjct: 562  GPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNK 621

Query: 2149 GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208
            G+ G+ G  G  G      GP G  G+ G  G+PG  G  G PG  G+ G  GR G  GA
Sbjct: 622  GEPGVVGAVGTAGPS----GPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGA 677

Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGP------RGSGGAAGAPGE 2262
             G  G PG  G  G++G  GA GPAGPAGP G  GE+G  GP       G  GAAG PG 
Sbjct: 678  PGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGA 737

Query: 2263 RGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGY---- 2318
            +G  G  G KGE G  GP G +G  GP G  G  G    GS G  G  G  GFPG     
Sbjct: 738  KGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPG--PAGSRGDGGPPGMTGFPGAAGRT 795

Query: 2319 --PGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373
              PGP G  G PG  G  G +G+RG RG+ GP G  G+ G  G PG AG KG  G++
Sbjct: 796  GPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEA 852



 Score =  268 bits (686), Expect = 5e-71
 Identities = 161/377 (42%), Positives = 189/377 (50%), Gaps = 44/377 (11%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGV------------NGTQGFQ 2085
            G  G  GP G  G  G PG  G++G  G+ G PG+ GP G             +G  G  
Sbjct: 91   GPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKP 150

Query: 2086 GCPGQRGV---KGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDK--- 2139
            G PG+RGV   +G+RGFPG  G  G  G+ G +G DG KG PG+ G KG PG  G+    
Sbjct: 151  GRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTP 210

Query: 2140 ---GPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGK 2196
               G RG  GERG VG  G  G  G D    GP G  G +G  G PG  G PG  GE G 
Sbjct: 211  GQTGARGLPGERGRVGAPGPAGARGSDGSV-GPVGPAGPIGSAGPPGFPGAPGPKGEIGA 269

Query: 2197 NGGFGRRGP---------PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGI 2247
             G  G  GP         PG  G  G PG PG  G  G +GA G  G AG PGL G +GI
Sbjct: 270  VGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGI 329

Query: 2248 SGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSE--- 2304
             GP G+ GA GA G  G  GP G KGE G  G  G  G +GP G +G++G+ G   E   
Sbjct: 330  PGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGS 389

Query: 2305 -------GRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNS---GPPGIVGQ 2354
                   G RG  G RG PG  G  G  G PG  G +GP G+RG  G++   G PG++G 
Sbjct: 390  AGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGP 449

Query: 2355 KGDPGYPGPAGPKGNRG 2371
            +G PG PG  GP G  G
Sbjct: 450  RGLPGSPGNIGPAGKEG 466



 Score =  264 bits (674), Expect = 1e-69
 Identities = 172/451 (38%), Positives = 204/451 (45%), Gaps = 111/451 (24%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGE---------------RGPPGVNGT 2081
            SG+ G RGP G  G  G PG  G RG PG  G PG                 GP GV G 
Sbjct: 375  SGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGP 434

Query: 2082 QGFQGCPGQRGVKGSRGFPGEKGEVGE------IGLDGLDGEDGDKGLPGSSGEKGNPGR 2135
             G  G PG+ G+ G RG PG  G +G       +GL G+DG  G  G  G+ GE GN G 
Sbjct: 435  NGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGF 494

Query: 2136 RGDKGPRGEKGERGD------VGIRGDPGNPGQDSQE-----RGPKGETGDLGPMGVPGR 2184
             G KGP G+ G+ GD       G RG PG  G +  +     +G +G  G+ GP G PG 
Sbjct: 495  PGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGF 554

Query: 2185 DGVPGG---------PGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGP 2235
             G+PG          PGE G +G FG  GP G +G +G PG+ G  G  G  G++GP+GP
Sbjct: 555  QGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGP 614

Query: 2236 AGPPGLIGEQGISGPRGSGGAAGA---PGERGRTGPLGRKGEPGEPGPKGGIGNRG---- 2288
             GP G  GE G+ G  G+ G +G    PGERG  G  G KGE GEPG +G IGN G    
Sbjct: 615  PGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGA 674

Query: 2289 -----------PRGETGDDGRDGV----------GSEGRRGKKGERGFPGYPGPKGNPGE 2327
                       P G TGD G  G           GS G RG+ G  G  G+ GP G  G+
Sbjct: 675  RGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQ 734

Query: 2328 PGLNGT---------------TGPKGIRGRRGNSGPPGIVGQKGD--------------- 2357
            PG  G                TGP G  G  G +GPPG  G +GD               
Sbjct: 735  PGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGR 794

Query: 2358 ------------PGYPGPAGPKGNRGDSIDQ 2376
                        PG PGPAG +G RG   DQ
Sbjct: 795  TGPPGPSGISGPPGPPGPAGKEGLRGPRGDQ 825



 Score =  263 bits (673), Expect = 2e-69
 Identities = 154/354 (43%), Positives = 172/354 (48%), Gaps = 28/354 (7%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGT---------------- 2081
            G  GDRGP G  GP G PG DG  G  G  G PG  GPPG+ G                 
Sbjct: 33   GPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGP 92

Query: 2082 ---QGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGD 2138
                G +G PG  G  G +GF G  GE GE G  G  G  G  G PG +GE G+PG+ G 
Sbjct: 93   MGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGR 152

Query: 2139 KGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNG 2198
             G RG  G +G  G  G PG PG     RG  G  G  G  G PG  G PG PGE G  G
Sbjct: 153  PGERGVVGPQGARGFPGTPGLPGFKG-IRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPG 211

Query: 2199 GFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAG 2258
              G RG PG +G  G PG  G  G  G+ G  GPAGP G  G  G  G  GP+G  GA G
Sbjct: 212  QTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVG 271

Query: 2259 APGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGY 2318
              G  G  GP G  G PG  GP G  GN G  G T        G++G  G  G  G PG 
Sbjct: 272  NAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLT--------GAKGAAGLPGVAGAPGL 323

Query: 2319 PGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
            PGP+G PG  G  G TG +G+ G  G +G  G  G KG+PG  GP GP G  G+
Sbjct: 324  PGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGE 377



 Score =  262 bits (670), Expect = 3e-69
 Identities = 160/390 (41%), Positives = 187/390 (47%), Gaps = 51/390 (13%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G+ G  GP G+ GP G PG+ G  G+PG  G PGERG  G  G +GF G PG  G KG R
Sbjct: 121  GEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIR 180

Query: 2098 GF------------PGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPG---RRGDKGPR 2142
            G             PG KGE G  G +G  G+ G +GLPG  G  G PG    RG  G  
Sbjct: 181  GHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSV 240

Query: 2143 GEKGERGDVGIRGDPGNPGQDSQE--------------RGPKGE---------------- 2172
            G  G  G +G  G PG PG    +               GP+GE                
Sbjct: 241  GPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNP 300

Query: 2173 -----TGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTR 2227
                 TG  G  G+PG  G PG PG  G  G  G  G  GA+G  G PG  G +GE G +
Sbjct: 301  GANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNK 360

Query: 2228 GAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNR 2287
            G  G AGP GPPG  GE+G  GP G  G+AG PG  G  G  G +G PG  G  G +G  
Sbjct: 361  GEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPP 420

Query: 2288 GPRGETGDDG-RDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNS 2346
            G RG +G  G R   G  GR G+ G  G  G PG  GN G  G  G  G  GI GR G  
Sbjct: 421  GSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPI 480

Query: 2347 GPPGIVGQKGDPGYPGPAGPKGNRGDSIDQ 2376
            GP G  G+ G+ G+PGP GP G+ G + D+
Sbjct: 481  GPAGARGEPGNIGFPGPKGPTGDPGKNGDK 510



 Score =  262 bits (669), Expect = 5e-69
 Identities = 162/380 (42%), Positives = 187/380 (49%), Gaps = 42/380 (11%)

Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQ 2085
            E+   G P    G  G RG  GS+GP G  G  G  G PG  G PG +G  G  G  G  
Sbjct: 221  ERGRVGAP----GPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPA 276

Query: 2086 GCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEK 2145
            G  G RG  G  G  G  G  G  G +GL G  G  GLPG +G  G PG RG  GP G  
Sbjct: 277  GPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAA 336

Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGP 2205
            G  G  G+ G+PG P     E G KGE G  GP G PG  G  G  G  G+ G  G  GP
Sbjct: 337  GATGARGLVGEPG-PAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGP 395

Query: 2206 PGAKGNKGGPGQPGFEGEQG------TRGAQGPAGPAGP---------PGLIGEQGISG- 2249
            PG +G+ G  G PG +G  G      +RGA GPAG  GP         PGL+G +G+ G 
Sbjct: 396  PGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGS 455

Query: 2250 -----PRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG---- 2300
                 P G  G  G PG  GR GP+G  G  GEP   G IG  GP+G TGD G++G    
Sbjct: 456  PGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEP---GNIGFPGPKGPTGDPGKNGDKGH 512

Query: 2301 ---VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGD 2357
                G+ G  G  G  G  G PGP+G  G  G  G  GP G +G  G SGP G VG+ G+
Sbjct: 513  AGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGE 572

Query: 2358 P------GYPGPAGPKGNRG 2371
                   G PGPAGP+G RG
Sbjct: 573  RGLHGEFGLPGPAGPRGERG 592



 Score =  260 bits (665), Expect = 1e-68
 Identities = 161/408 (39%), Positives = 194/408 (47%), Gaps = 72/408 (17%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKG-- 2095
            G+RG  GP G+ G  G PG  G++G  G  G  G +G PG  G +G  G PG+ G  G  
Sbjct: 154  GERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQT 213

Query: 2096 -SRGFPGEKGEVGEIGLDGLDGEDGD---------------KGLPGSSGEKGNPGRRGDK 2139
             +RG PGE+G VG  G  G  G DG                 G PG+ G KG  G  G+ 
Sbjct: 214  GARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNA 273

Query: 2140 GPRGEKGERGDVGIRG------DPGNPGQDSQER-----------------GPKGETGDL 2176
            GP G  G RG+VG+ G       PGNPG +                     GP+G  G +
Sbjct: 274  GPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPV 333

Query: 2177 GPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPA 2236
            G  G  G  G+ G PG  G  G  G +G PG+ G +G PG  G EG++G  G  G AGP 
Sbjct: 334  GAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPP 393

Query: 2237 GPPGLIGEQG------------ISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKG-- 2282
            GPPGL G  G            + GP GS GA+G  G RG  G  GR GEPG  GP+G  
Sbjct: 394  GPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLP 453

Query: 2283 -------GIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGE------- 2327
                     G  GP G  G DGR G +G  G RG+ G  GFPG  GP G+PG+       
Sbjct: 454  GSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHA 513

Query: 2328 --PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373
               G  G  GP G  G +G  GP G+ G KG+ G PGP G +G  G S
Sbjct: 514  GLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPS 561



 Score =  254 bits (650), Expect = 7e-67
 Identities = 153/358 (42%), Positives = 179/358 (50%), Gaps = 21/358 (5%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRG 2092
            P   +G  G  GP G  G +G  G  G  G+PG  G  G  GP G++G  G  G  G+ G
Sbjct: 758  PVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEG 817

Query: 2093 VKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVG 2152
            ++G RG  G  G  GE+G  G  G  G+KG  G +G  G PG  G +G  G  G  G  G
Sbjct: 818  LRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPG 877

Query: 2153 IRGDPGNPGQDSQ--ERGP---KGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPG 2207
             RG+ G PG      E GP    G  G  GP G  G  GV G PGE G++G  G  GPPG
Sbjct: 878  SRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPG 937

Query: 2208 AKG---NKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERG 2264
              G   +KG  G PG  G  G  GA GP GP GP G  G +G +GP G  G AGA G RG
Sbjct: 938  RDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRG 997

Query: 2265 RTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-------GSEGRRGKKGERGFPG 2317
             +GP G +G+ GEPG KG  G  G +G  G  G  G+       G+ G  G  G RG  G
Sbjct: 998  PSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAG 1057

Query: 2318 YPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSID 2375
              GP G  G  G  GT GP GIRG +G+ GP       G PG PGP GP G  G   D
Sbjct: 1058 PSGPAGKDGRTGHPGTVGPAGIRGPQGHQGP------AGPPGPPGPPGPPGVSGGGYD 1109



 Score =  214 bits (546), Expect = 8e-55
 Identities = 134/312 (42%), Positives = 151/312 (48%), Gaps = 34/312 (10%)

Query: 2094 KGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGD-------------KG 2140
            KG  G  G +GE G  G  G DGEDG  G PG  G  G PG  G+              G
Sbjct: 32   KGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPG 91

Query: 2141 PRGEKGERGDVGIRGDPG-----NPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETG 2195
            P G  G RG  G  G PG      P  +  E G  G  G  GP G PG+ G  G PG+ G
Sbjct: 92   PMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPG 151

Query: 2196 KNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGG 2255
            + G  G  GP GA+G  G PG PGF+G +G  G  G  G  G PG+ GE G  G  G+ G
Sbjct: 152  RPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPG 211

Query: 2256 AAGA---PGERGRT---GPLGRKGEPGE---PGPKGGIGNRGPRGETGDDGRDG------ 2300
              GA   PGERGR    GP G +G  G     GP G IG+ GP G  G  G  G      
Sbjct: 212  QTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVG 271

Query: 2301 -VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPG 2359
              G  G  G +GE G PG  GP G PG PG NG TG KG  G  G +G PG+ G +G PG
Sbjct: 272  NAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPG 331

Query: 2360 YPGPAGPKGNRG 2371
              G AG  G RG
Sbjct: 332  PVGAAGATGARG 343



 Score =  198 bits (503), Expect = 8e-50
 Identities = 117/272 (43%), Positives = 137/272 (50%), Gaps = 8/272 (2%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096
            +G++G  G  G+ GP G PG  G  G PG  G PG RG  G+ G  G  G PG  G+ G 
Sbjct: 843  AGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGP 902

Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGD 2156
             G  G  G VG  G++G  GE G  G PG+ G  G  G+ G KG RG  G  G VG  G 
Sbjct: 903  PGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGA 962

Query: 2157 PG--NPGQDSQERGPKGETGDLGPMGVPGRDGV--PGGP----GETGKNGGFGRRGPPGA 2208
            PG   P   + + G +GETG  GP+G  G  G   P GP    G+ G+ G  G RG PG 
Sbjct: 963  PGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGL 1022

Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2268
            KG+ G  G PG  G  G +GA G  GPAGP G  G  G +G  G  G  G  G  G  GP
Sbjct: 1023 KGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGP 1082

Query: 2269 LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG 2300
             G +G  G PGP G  G  G  G   D G DG
Sbjct: 1083 QGHQGPAGPPGPPGPPGPPGVSGGGYDFGYDG 1114



 Score =  165 bits (418), Expect = 6e-40
 Identities = 97/226 (42%), Positives = 113/226 (50%), Gaps = 14/226 (6%)

Query: 2162 QDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGN-------KG- 2213
            +++  +GP G+ G  G  G PG  G  G  G TG  G  G  GPPG  GN       KG 
Sbjct: 27   EETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGV 86

Query: 2214 --GPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGR 2271
              GPG  G  G +G  GA G  GP G  G  GE G  G  G  GA G  G  G+ G  G 
Sbjct: 87   GLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGH 146

Query: 2272 KGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGL 2330
             G+PG PG +G +G +G RG  G  G  G  G  G  G  G +G PG PG KG PG PG 
Sbjct: 147  PGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGE 206

Query: 2331 NGT---TGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373
            NGT   TG +G+ G RG  G PG  G +G  G  GP GP G  G +
Sbjct: 207  NGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSA 252



 Score =  164 bits (414), Expect = 2e-39
 Identities = 98/239 (41%), Positives = 113/239 (47%), Gaps = 4/239 (1%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096
            +G  G+ GP+G  GP G  G  G  G PG  G PGE G  G  G  G  G  GQ G KG 
Sbjct: 888  AGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGE 947

Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGD 2156
            RG+PG  G VG  G  G  G  G  G  G+ GE G  G  G  G  G +G  G  GIRGD
Sbjct: 948  RGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGD 1007

Query: 2157 PGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPG 2216
             G PG    E+GP+G  G  G  G+ G  G+ G  G+ G  G  G  GP G  G  G  G
Sbjct: 1008 KGEPG----EKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAG 1063

Query: 2217 QPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEP 2275
            + G  G  GT G  G  GP G  G  G  G  GP G  G +G   + G  G   R  +P
Sbjct: 1064 KDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSGGGYDFGYDGDFYRADQP 1122



 Score = 79.7 bits (195), Expect = 4e-14
 Identities = 49/127 (38%), Positives = 58/127 (45%), Gaps = 12/127 (9%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRG 2092
            P    G RGD+G  G  GP+G+PG  G+ G          +G PG+ G  G QG PG  G
Sbjct: 998  PSGPQGIRGDKGEPGEKGPRGLPGLKGHNGL---------QGLPGIAGHHGDQGAPGSVG 1048

Query: 2093 VKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERG--- 2149
              G RG  G  G  G+ G  G  G  G  G+ G  G +G  G  G  GP G  G  G   
Sbjct: 1049 PAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSGGGY 1108

Query: 2150 DVGIRGD 2156
            D G  GD
Sbjct: 1109 DFGYDGD 1115


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  277 bits (708), Expect = 1e-73
 Identities = 160/356 (44%), Positives = 193/356 (54%), Gaps = 38/356 (10%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G  GDRGPIG  G  G PG+ G    PG++G PG  GPPG  G +G  G  G++G +G  
Sbjct: 1589 GDPGDRGPIGLTGRAGPPGDSGP---PGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPP 1645

Query: 2098 GFPGEKGEVGEIGLDGLD------GEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDV 2151
            G PG  G+ GE GL G        GE GD+G PG  G  G+PG  G KG RGE G  G  
Sbjct: 1646 GDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPP 1705

Query: 2152 G----------IRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFG 2201
            G           +G+PG+ GQ+    GP+G  GD G  G PG  G+ G  G  G  G  G
Sbjct: 1706 GRLVDTGPGAREKGEPGDRGQE----GPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPG 1761

Query: 2202 RRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGP------------PGLIGEQGISG 2249
             RGP G KG++G PG  G  G  G  GA GP+GP G             PGL GEQG+ G
Sbjct: 1762 VRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPG 1821

Query: 2250 PRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRG 2308
            P G  G  G PGE G+ G  G+ GEPG+PG  G  G +G  G +G +GRDG  G  G  G
Sbjct: 1822 PSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPG 1881

Query: 2309 KKGERGFPGYPGPKGNPGE--PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPG 2362
              G +G PG PGP G PG+  PG+ G TGPKG RG  G+ G  G+ G++G  G PG
Sbjct: 1882 ILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPG 1937



 Score =  276 bits (707), Expect = 2e-73
 Identities = 167/373 (44%), Positives = 204/373 (54%), Gaps = 44/373 (11%)

Query: 2038 GQRGDRGPIGSIGPKGIPG--EDGYRGYPGDEGGPGE---RGPPGVNGTQGFQGCPG--- 2089
            G  G +GP+G  G KG  G  EDG  G PG  G PGE   RGPPG  G +G +G PG   
Sbjct: 1430 GSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLG 1489

Query: 2090 QRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSG---EKGNPGRRGDK------- 2139
            + G KG RG PG  G  G  G+ G  G  G +G PG +G   EKG PGR GD        
Sbjct: 1490 EAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAV 1549

Query: 2140 -GPRGEKGE------RGDVGIRGDPGNPGQDSQ-ERGPKGETGDLGPMGVPGRDGVPGGP 2191
             GP+GEKG+      RG  G++G+ G PG     + GPKG+ GD GP+G+ GR G PG  
Sbjct: 1550 AGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDS 1609

Query: 2192 GETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPR 2251
            G  G+ G  GR GPPG  G +G  G+ G +G++G  G  G  G AG  GL G  G+ GP 
Sbjct: 1610 GPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPV 1669

Query: 2252 GSGGAAGAPGERGR------TGPLGRKGEPGEPGPKGGIGNRGP----RGETGDDGRDGV 2301
            G  G  G PGE GR      +GP G +GEPG PGP G + + GP    +GE GD G+   
Sbjct: 1670 GEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQ--- 1726

Query: 2302 GSEGRRGKKGERGFPGYPGPKGNP---GEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDP 2358
              EG RG KG+ G PG PG +G     G PG  G  G +G  G +G+ GPPG+ G+ G  
Sbjct: 1727 --EGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLD 1784

Query: 2359 GYPGPAGPKGNRG 2371
            G PG AGP G  G
Sbjct: 1785 GKPGAAGPSGPNG 1797



 Score =  274 bits (700), Expect = 1e-72
 Identities = 167/401 (41%), Positives = 206/401 (51%), Gaps = 68/401 (16%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G++G RGP G+IGPKG   + G+ G  G+ G  GERGPPG  G++G  G  G+ G KG  
Sbjct: 1465 GEQGPRGPPGAIGPKG---DRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPE 1521

Query: 2098 GFPG------EKGEVGEIG--------LDGLDGEDGD------KGLPGSSGEKGNPGR-- 2135
            G PG      EKGE G  G        + G  GE GD      +G  G  GE+G PG   
Sbjct: 1522 GPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVL 1581

Query: 2136 RGDKGPRGEKGERGDVGI---------------RGDPGNPGQDSQ--ERGPKGETGDLGP 2178
             GD GP+G+ G+RG +G+               +GDPG PG       RG  GE G+ G 
Sbjct: 1582 PGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGD 1641

Query: 2179 MGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQ------PGFEGEQGTRGAQGP 2232
             G PG  G+PG  GE G  G  G RGP G KG++G PG+      PG  G +G RG  GP
Sbjct: 1642 EGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGP 1701

Query: 2233 AGPAG-------------PPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPG 2279
             GP G              PG  G++G  GP+G  G  GAPGERG  G  G  G  G+PG
Sbjct: 1702 PGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPG 1761

Query: 2280 PKGGIGNRGPRGETGDDGRDGV-------GSEGRRGKKGERGFPGYPGPKGNPGEPGLNG 2332
             +G  G +G RG  G DGR G+       G  G  G  G+ G PG  G  G  GE GL G
Sbjct: 1762 VRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPG 1821

Query: 2333 TTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373
             +GP G+ G+ G  G PG+ G+ G+PG PG  G KG +GDS
Sbjct: 1822 PSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDS 1862



 Score =  271 bits (692), Expect = 1e-71
 Identities = 166/411 (40%), Positives = 205/411 (49%), Gaps = 69/411 (16%)

Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQ 2090
            GVP    G  G  G  G +G  G+PG  G  G+PG  G  GE G PG +G +G  G PG+
Sbjct: 2374 GVPGS-PGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGR 2432

Query: 2091 RGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKG--LPGSSGEKGNPGRRGDKG-------- 2140
             G+ G  G PG  G VG  G  GL G+ GD G  LPG  GE+G PG RG+ G        
Sbjct: 2433 EGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPR 2492

Query: 2141 -------PRGEKGERGDVG---IRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGG 2190
                    RGE+GE+GDVG   ++GD G+        GP+G  GD+G  G  G DG  G 
Sbjct: 2493 GLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGP 2552

Query: 2191 PGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQG-PAGPAGP-----PGLIGE 2244
             G+ G  G  G +G PG KG+ G PG  G  G QG  GA G P  P  P     PG+ GE
Sbjct: 2553 RGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGE 2612

Query: 2245 QG---ISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV 2301
            +G     GPRG  G  G  G  G  G  G KGE G PG  G  G++G  GE G  G+ G 
Sbjct: 2613 KGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGA 2672

Query: 2302 -GSEGRRGKKGERGFPGYPGPKGN---------------------------PGEPGLNGT 2333
             G EG  G KG+RGF G PGPKG+                           PG PG  G 
Sbjct: 2673 PGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGP 2732

Query: 2334 TGPKGIRGRRGNSGP-----------PGIVGQKGDPGYPGPAGPKGNRGDS 2373
             GP+G++G++G  GP           PG  G++G+ G PGPAGP+G +G++
Sbjct: 2733 RGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEA 2783



 Score =  266 bits (681), Expect = 2e-70
 Identities = 177/397 (44%), Positives = 201/397 (50%), Gaps = 67/397 (16%)

Query: 2030 CGVPCKCSGQRGDRGPIG---SIGPKGIPGEDGYRGYPGDEGGPG------ERGPPGVNG 2080
            C V C   GQ+G+ G +G    +GP G PG  G  G PG +G PG      ERG PG +G
Sbjct: 1247 CPVYCP-KGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADG 1305

Query: 2081 TQGFQG------CPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPG 2134
              G  G       PG  G+KGS G PG +G+ GE G  G  GE G  G        G PG
Sbjct: 1306 RPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPG 1365

Query: 2135 RRGDKGPRGEKGER---GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGV---- 2187
            R+GD GP G  G R   GD G RG PG PG  +  +G KG+ G+ GP G PG  G+    
Sbjct: 1366 RKGDPGPSGPPGPRGPLGDPGPRGPPGLPG--TAMKGDKGDRGERGPPG-PGEGGIAPGE 1422

Query: 2188 PGGPGETGKNGGFGRRGPPGAKGNKGG--------PGQPGFEGEQGTRGAQGPAGP---- 2235
            PG PG  G  G  G  GPPG KG KG         PGQPG  GEQG RG  G  GP    
Sbjct: 1423 PGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDR 1482

Query: 2236 --AGPPGLIGEQGISGPRGSGGAAGAPGERGR---------TGPLGRKGEPGEPGPKG-- 2282
               GP G  GE+G  GP G  G+ G PG  GR          GP GR+GE GEPG  G  
Sbjct: 1483 GFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDP 1542

Query: 2283 ---GIGNRGPRGETGDDGRDGVGSEGRRGKKGERG-----FPGYPGPKGNPGEPGLNGTT 2334
               G    GP+GE GD G    G  G  G +GERG      PG PGPKG+PG+       
Sbjct: 1543 AVVGPAVAGPKGEKGDVG--PAGPRGATGVQGERGPPGLVLPGDPGPKGDPGD------R 1594

Query: 2335 GPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
            GP G+ GR G  G  G  G+KGDPG PGP GP G RG
Sbjct: 1595 GPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRG 1631



 Score =  266 bits (680), Expect = 2e-70
 Identities = 170/413 (41%), Positives = 196/413 (47%), Gaps = 79/413 (19%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGIP---------------------GEDGYRGYPGDEGGPG 2071
            P    G  G  GP G +GP+G P                     G+DG RG PG  G PG
Sbjct: 2222 PTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPG 2281

Query: 2072 ERGPPGVNGTQGFQGCPGQR-------------------------GVKGSRGFP---GEK 2103
              GP G  G  G  G PGQ                          G KG RG P   GEK
Sbjct: 2282 LPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEK 2341

Query: 2104 GEVGEIGLDGLDGEDGDKGLPGSSGEKGNP--GRRGDKGPRGEKGERGDVGIRGDPGNPG 2161
            GE G  G  G  GEDG KG PG  G KG+P  G  G  GP G  G +GD+G+ G PG PG
Sbjct: 2342 GEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPG 2401

Query: 2162 QDS--QERGPKGETGDLGP------MGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKG 2213
                  + GP+GE G  GP       G PGR+G+PG  G  G  G  G  G  G KG+KG
Sbjct: 2402 VVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKG 2461

Query: 2214 GP-----------GQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE 2262
             P           G+PG  GE G  G +GP G  GPPG  GE+G  G  GS G  G  G+
Sbjct: 2462 DPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGD 2521

Query: 2263 R----GRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGY 2318
                 G  GP G KG+ GE GP+G  G++GPRG+ GD G    GS+G  G KG  G PG 
Sbjct: 2522 SAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPG--DKGSKGEPGDKGSAGLPGL 2579

Query: 2319 PGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
             G  G  G+PG  G  G  G  G+    G PGI G+KGD G+ GP G KG RG
Sbjct: 2580 RGLLGPQGQPGAAGIPGDPGSPGK---DGVPGIRGEKGDVGFMGPRGLKGERG 2629



 Score =  266 bits (679), Expect = 3e-70
 Identities = 177/428 (41%), Positives = 216/428 (50%), Gaps = 90/428 (21%)

Query: 2031 GVPCKCSGQRGDRGPIGSI---GPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGF--- 2084
            G+P + +G  G +GP GS    G +G PG DG  G PG  G PG  G PG+ G+ G    
Sbjct: 1275 GLPGR-TGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGP 1333

Query: 2085 QGCPGQRGVKGSRGFPGEKGEV--GE-IGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGP 2141
            +G PG+RG +G +G PG  G+V  GE  GL G  G+ G  G PG  G  G+PG RG  G 
Sbjct: 1334 RGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGL 1393

Query: 2142 RGE--KGERGDVGIRGDPGNPGQDSQERGPKG------ETGDLGPMGVPGR--------D 2185
             G   KG++GD G RG PG PG+     G  G        G  GP+G PG+        D
Sbjct: 1394 PGTAMKGDKGDRGERGPPG-PGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSED 1452

Query: 2186 GVPGGPGETGKNGGFGRRGPPGA---KGNKGGPGQPGFEGEQGTRGAQGPAG-------- 2234
            G PG PG+ G  G  G RGPPGA   KG++G PG  G  GE+G RG  GPAG        
Sbjct: 1453 GAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVA 1512

Query: 2235 -------PAGPPGLIGEQG-----------------ISGPRGSGGAAGAPGERGRTGPLG 2270
                   P GPPG  G QG                 ++GP+G  G  G  G RG TG  G
Sbjct: 1513 GRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQG 1572

Query: 2271 RKGEPG-----EPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGP---- 2321
             +G PG     +PGPKG  G+RGP G TG  G  G    G  G+KG+ G PG PGP    
Sbjct: 1573 ERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPG--DSGPPGEKGDPGRPGPPGPVGPR 1630

Query: 2322 -----------KGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDP------GYPGPA 2364
                       +G PG+PGL G  G +G+RG  G  GP G  G +GDP      G PG +
Sbjct: 1631 GRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSS 1690

Query: 2365 GPKGNRGD 2372
            GPKG+RG+
Sbjct: 1691 GPKGDRGE 1698



 Score =  265 bits (676), Expect = 7e-70
 Identities = 163/376 (43%), Positives = 186/376 (49%), Gaps = 40/376 (10%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G  G  G +G  G  G PG DG  G  GD G PG  G PG+ G  G +G PG  G  G  
Sbjct: 2242 GSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQA 2301

Query: 2098 --GFPGEKGEVGEIG-----LDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD 2150
              G PG KGE G  G     L G  G  GD+GLPG  GEKG  GR G+ G  GE G++G 
Sbjct: 2302 VVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGA 2361

Query: 2151 VGIRGDPGNPGQ----DSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPP 2206
             G +G  G+PG          GP G  GDLG  G+PG  GV G PG+TG  G  G+ GP 
Sbjct: 2362 PGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPS 2421

Query: 2207 GAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQG-----ISGPRGSGGAAGAPG 2261
            G +G  G PG+ G  G  G  G  G  GP G  GL G++G     + GPRG  G  G  G
Sbjct: 2422 GERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRG 2481

Query: 2262 ERGR---------TGPLGRKGEPGEPGPKGGIGNRG-------------PRGETGDDGRD 2299
            E GR         TGP G +GE GE G  G  G +G             PRG  GD G  
Sbjct: 2482 EDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGER 2541

Query: 2300 GVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPG 2359
            G    G  G KG RG  G PG KG+ GEPG  G+ G  G+RG  G  G PG  G  GDPG
Sbjct: 2542 G--PRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPG 2599

Query: 2360 YPGPAGPKGNRGDSID 2375
             PG  G  G RG+  D
Sbjct: 2600 SPGKDGVPGIRGEKGD 2615



 Score =  265 bits (676), Expect = 7e-70
 Identities = 165/380 (43%), Positives = 196/380 (51%), Gaps = 46/380 (12%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGER--GPPGVNGTQGFQG-----CPG 2089
            SG+ GDRG  G  G  G+PG  G +G PG  G PG+   G PG  G +G  G       G
Sbjct: 2265 SGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVG 2324

Query: 2090 QRGVKGSRGFPG---EKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRR--GDKGPRGE 2144
            + G KG RG PG   EKGE G  G  G  GEDG KG PG  G KG+PG    G  GP G 
Sbjct: 2325 EPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGP 2384

Query: 2145 KGERGDVGIRGDPGNPGQDS--QERGPKGETGDLGPMGV------PGRDGVPGGPGETGK 2196
             G +GD+G+ G PG PG      + GP+GE G  GP G       PGR+G+PG  G  G 
Sbjct: 2385 PGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGP 2444

Query: 2197 NGGFGRRGPPGAKGNKGGPG-----------QPGFEGEQGTRGAQGPAGPAGPPGLIGEQ 2245
             G  G  G  G KG+KG PG           +PG  GE G  G +GP G  GPPG  GE+
Sbjct: 2445 PGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGER 2504

Query: 2246 GISGPRGSGGAAGAPGER----GRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV 2301
            G  G  GS G  G  G+     G  GP G KG+ GE GP+G  G++GPRG+ GD G  G 
Sbjct: 2505 GEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKG- 2563

Query: 2302 GSEGRRGKKGERGFPGYPG---PKGNPGE---PGLNGTTGPKGIRGRRGNSGPPGIVGQ- 2354
             S+G  G KG  G PG  G   P+G PG    PG  G+ G  G+ G RG  G  G +G  
Sbjct: 2564 -SKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPR 2622

Query: 2355 --KGDPGYPGPAGPKGNRGD 2372
              KG+ G  G  G  G +GD
Sbjct: 2623 GLKGERGVKGACGLDGEKGD 2642



 Score =  262 bits (670), Expect = 3e-69
 Identities = 161/383 (42%), Positives = 190/383 (49%), Gaps = 49/383 (12%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPG-----DEGGPG---ERGPPGVNGTQGFQGCPG 2089
            G++G+RG  G  GP G+PG  G  G PG     DE GPG   E+GPPG+ G +G  G  G
Sbjct: 2064 GEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNG 2123

Query: 2090 QRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERG 2149
             +G KG RG PG KG+ GE G  G DG  G  G  G +G +G PG +G +GP G  G  G
Sbjct: 2124 DQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHG 2183

Query: 2150 DVGIRGDPG--NPGQDSQERGPKGETGDLGP-----------------------MGVPGR 2184
            D G  G PG   P       G KGE G+ GP                       +G  G 
Sbjct: 2184 DPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGS 2243

Query: 2185 DGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPG--LI 2242
             G+PG  GETGK G  GR G  G  G++G PG PG  G  G  G +G  GP G PG  ++
Sbjct: 2244 PGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVV 2303

Query: 2243 GEQGISGPRGS-GGAAG-------------APGERGRTGPLGRKGEPGEPGPKGGIGNRG 2288
            G  G  G +G+ GG AG              PG RG  G  GR GEPG+PG  G  G  G
Sbjct: 2304 GLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPG 2363

Query: 2289 PRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGP 2348
            P+G  GD G    GS G  G  G +G  G PG  G PG  G  G TGP+G  G+ G SG 
Sbjct: 2364 PKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGE 2423

Query: 2349 PGIVGQKGDPGYPGPAGPKGNRG 2371
             G+ G  G  G PGP GP G  G
Sbjct: 2424 RGLAGPPGREGIPGPLGPPGPPG 2446



 Score =  260 bits (665), Expect = 1e-68
 Identities = 160/366 (43%), Positives = 184/366 (50%), Gaps = 39/366 (10%)

Query: 2038 GQRGDRGPIGS---IGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094
            G  GD GP G+    GP G  G  G +G PG+ G PG RG  G  G  G  G PG  G+ 
Sbjct: 2180 GGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPG-RGLTGPTGAVGLPGPPGPSGLV 2238

Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154
            G +G PG  G+VGE G  G  G DG  G  G  G  G PG  G  GP G KGE G  G  
Sbjct: 2239 GPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAP 2298

Query: 2155 GDP--GNPGQDSQERGPKGETGDL-GPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGN 2211
            G    G PG   ++  P G  GDL G  G  G  G+PG  GE G+ G  G  G PG  G 
Sbjct: 2299 GQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQ 2358

Query: 2212 KGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGI---------------SGPRGSGGA 2256
            KG PG  GF+G+ G  G  G  GP GPPG+ G+ G+               +GPRG  G 
Sbjct: 2359 KGAPGPKGFKGDPGV-GVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQ 2417

Query: 2257 AGAPGERGRTGPLGRKGEPGE---PGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGER 2313
             G  GERG  GP GR+G PG    PGP G +G  G  G  GD G  GVG  G RG++GE 
Sbjct: 2418 PGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGE- 2476

Query: 2314 GFPGYPGPKGN---PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPG----YPGPAGP 2366
                 PG +G    PG+ G  G TGP G RG RG  G  G  G KGD G      GP GP
Sbjct: 2477 -----PGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGP 2531

Query: 2367 KGNRGD 2372
            +G +GD
Sbjct: 2532 RGAKGD 2537



 Score =  259 bits (661), Expect = 4e-68
 Identities = 169/439 (38%), Positives = 208/439 (47%), Gaps = 104/439 (23%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGS 2096
            +G++GDRGP G  G  G+ G+ G  G  G  G  G+ G PG +G  G +G  G  G  G 
Sbjct: 1766 AGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGP 1825

Query: 2097 RGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPG---RRGDKGPRGEKGERGDVGI 2153
             G PG+ GE G+ GL+G +GE GD G  G  GEKG+ G   R G  GP+GE+G  G +G 
Sbjct: 1826 PGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGP 1885

Query: 2154 RGDPGNPGQ-------------DSQERGPKGETGDLGPMGVPGRDGVPGGPG-------- 2192
            +G PG PG               +  +G +GETG  G  G+PG  G+ G PG        
Sbjct: 1886 QGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRL 1945

Query: 2193 -ETG----------------KNGGF-----GRRGPPGAKGNKGGPGQP---GFEGEQGTR 2227
             ET                  +G F      RRGP G  G +G PG+    GF GE+G +
Sbjct: 1946 LETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLK 2005

Query: 2228 GAQGPAGPAGPPGL-IGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGN 2286
            G +G  GP GPPGL +GE+G  GP G  G  G PG  G  G  G  GE G PG +G  G 
Sbjct: 2006 GDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGE 2065

Query: 2287 RGPRGETGDDGRDGV---------------------------------------GSEGRR 2307
            +G RGE G DG  G+                                       GS G +
Sbjct: 2066 KGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQ 2125

Query: 2308 GKKGERGFPGY------PGPK---GNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDP 2358
            G KG+RG PG       PGP+   GNPG PG  G  GP+G  G +G  GPPG VG  GDP
Sbjct: 2126 GPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDP 2185

Query: 2359 GYP------GPAGPKGNRG 2371
            G P      GPAGP+G  G
Sbjct: 2186 GPPGAPGLAGPAGPQGPSG 2204



 Score =  259 bits (661), Expect = 4e-68
 Identities = 165/382 (43%), Positives = 188/382 (49%), Gaps = 66/382 (17%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGV----------------NGT 2081
            G  G++GP G  GP G PGE   RG  GD G PG +GPPG+                 G 
Sbjct: 1982 GDSGEQGPPGKEGPIGFPGE---RGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGK 2038

Query: 2082 QGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRR----- 2136
             G  G PG+ G  G  G PGE+GE GE G  G  G DG  GLPG+ G  G PG +     
Sbjct: 2039 PGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDE 2098

Query: 2137 ------GDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGG 2190
                  G++GP G KG +G+ G  GD G  G    +RG  G  GD G  G  G+DG PG 
Sbjct: 2099 PGPGLSGEQGPPGLKGAKGEPGSNGDQGPKG----DRGVPGIKGDRGEPGPRGQDGNPGL 2154

Query: 2191 PGE------TGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGE 2244
            PGE       GK G  G RGPPG  G  G PG P      G  G  GPAGP GP GL GE
Sbjct: 2155 PGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPP------GAPGLAGPAGPQGPSGLKGE 2208

Query: 2245 QGISGPRGSG-----GAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRD 2299
             G +GP G G     GA G PG  G +G +G +G PG PG  G  G  G  G  G  G+D
Sbjct: 2209 PGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKD 2268

Query: 2300 GVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPK--GIRGRRGNSGPPG-----IV 2352
                 G RG  G  G PG PGP G  GEPG  G  G    G+ G +G  G PG     +V
Sbjct: 2269 -----GDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLV 2323

Query: 2353 GQ---KGDPGYPGPAGPKGNRG 2371
            G+   KGD G PGP G KG  G
Sbjct: 2324 GEPGAKGDRGLPGPRGEKGEAG 2345



 Score =  258 bits (658), Expect = 9e-68
 Identities = 165/401 (41%), Positives = 189/401 (47%), Gaps = 82/401 (20%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGD------------------------------ 2066
            +G +GDRG  GS G +G+PGE G RG PG                               
Sbjct: 1909 TGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSG 1968

Query: 2067 ------------EGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPG----------EKG 2104
                        +G  GE+GPPG  G  GF   PG+RG+KG RG PG          E+G
Sbjct: 1969 SFLPVPERRRGPKGDSGEQGPPGKEGPIGF---PGERGLKGDRGDPGPQGPPGLALGERG 2025

Query: 2105 EVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDS 2164
              G  GL G  G+ G  GLPG +G  G  GR G++G RGEKGERG+ G  G PG PG   
Sbjct: 2026 PPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPG 2085

Query: 2165 QER--GPKGETGDLGP-----MGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQ 2217
                 GPK    + GP      G PG  G  G PG  G  G  G RG PG KG++G PG 
Sbjct: 2086 PPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGP 2145

Query: 2218 PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGR------ 2271
             G +G  G  G +G AGP G PGL G +G  GP G  G  G PG  G  GP G       
Sbjct: 2146 RGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGL 2205

Query: 2272 KGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNPGEPGL 2330
            KGEPGE GP G       RG TG  G  G+ G  G  G  G +G PG PG  G  G+PG 
Sbjct: 2206 KGEPGETGPPG-------RGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGA 2258

Query: 2331 NGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
             G  G  G  G RG+ G P      G PG PGP GPKG  G
Sbjct: 2259 PGRDGASGKDGDRGSPGVP------GSPGLPGPVGPKGEPG 2293



 Score =  256 bits (654), Expect = 2e-67
 Identities = 162/408 (39%), Positives = 188/408 (46%), Gaps = 73/408 (17%)

Query: 2031 GVPCKCSGQRGDRGP------------------IGSIGPKGIPGEDGYRGYPGDEGGPGE 2072
            G P    G+RG  GP                   G +G  G PGE G RG  G+ G  G 
Sbjct: 2015 GPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGR 2074

Query: 2073 RGPPGVNGTQGFQGCPGQR--------GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLP 2124
             GPPG+ GT G  G PG +        G+ G +G PG KG  GE G +G  G  GD+G+P
Sbjct: 2075 DGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVP 2134

Query: 2125 GSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPG--------NPGQDSQERGPKGETGDL 2176
            G  G++G PG RG  G  G  GERG  G  G PG         P     + GP G  G  
Sbjct: 2135 GIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLA 2194

Query: 2177 GPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPA 2236
            GP G  G  G+ G PGETG  G  G  GP GA G  G PG  G  G QG+ G  G  G  
Sbjct: 2195 GPAGPQGPSGLKGEPGETGPPGR-GLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGET 2253

Query: 2237 GPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEP--------------------- 2275
            G PG  G  G SG  G  G+ G PG  G  GP+G KGEP                     
Sbjct: 2254 GKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKG 2313

Query: 2276 ----------GEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNP 2325
                      GEPG KG  G  GPRGE G+ GR      G  G  GE G  G PGPKG  
Sbjct: 2314 APGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGR-----AGEPGDPGEDGQKGAPGPKGFK 2368

Query: 2326 GEPGLN--GTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
            G+PG+   G+ GP G  G +G+ G PG+ G  G  G+PG  GP+G  G
Sbjct: 2369 GDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMG 2416



 Score =  256 bits (653), Expect = 3e-67
 Identities = 165/397 (41%), Positives = 191/397 (48%), Gaps = 58/397 (14%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPG-EDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQR 2091
            P    G+RG +G  G  GP+G PG   G RG PG  G  GE G PG+ G  G  G  G+ 
Sbjct: 1995 PIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEA 2054

Query: 2092 GVKGSRGFPGEKGEVGEIGLDGL-----------------------DGEDGDKGLPGSSG 2128
            G  G RG  GEKGE GE G DG                         G  G++G PG  G
Sbjct: 2055 GRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKG 2114

Query: 2129 EKGNPGRRGDKGPRGE------KGERGDVGIRGDPGNPGQDSQE--RGPKGETGDLGPMG 2180
             KG PG  GD+GP+G+      KG+RG+ G RG  GNPG   +    GP+G+ G  GP G
Sbjct: 2115 AKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRG 2174

Query: 2181 VP---GRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAG 2237
             P   G  G PG PG  G  G  G +GP G KG  G  G PG  G  G  GA G  GP G
Sbjct: 2175 PPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPG-RGLTGPTGAVGLPGPPG 2233

Query: 2238 PPGLIGEQ---GISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETG 2294
            P GL+G Q   G+ G  G  G  GAPG  G +G  G +G PG PG  G  G  GP+GE G
Sbjct: 2234 PSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPG 2293

Query: 2295 DDGRDGVGSEGRRGKKGERGFP-----------------GYPGPKGNPGEPGLNGTTGPK 2337
              G  G    G  G KGE+G P                 G PGP+G  GE G  G  G  
Sbjct: 2294 PTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDP 2353

Query: 2338 GIRGRRGNSGPPGIVGQK--GDPGYPGPAGPKGNRGD 2372
            G  G++G  GP G  G    G PG PGP GP G +GD
Sbjct: 2354 GEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGD 2390



 Score =  249 bits (635), Expect = 4e-65
 Identities = 166/458 (36%), Positives = 196/458 (42%), Gaps = 121/458 (26%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSR 2097
            G++GD GP G  G  G  GE G RG PG  G  GE+G  G  G  G  G PG  G KG R
Sbjct: 1637 GEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDR 1696

Query: 2098 GFPG----------------EKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGP 2141
            G PG                EKGE G+ G +G  G  GD GLPG+ GE+G  G RG  GP
Sbjct: 1697 GEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGP 1756

Query: 2142 RGEKGERGDVGIRGDPGNPGQDSQE--------RGPKGETGDLGPMGVPGRDGVPG---- 2189
            +G+ G RG  G +GD G PG D +          GP G  G  G  G PGRDG+PG    
Sbjct: 1757 QGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGE 1816

Query: 2190 --------------GPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGP 2235
                           PGE GK G  G+ G PG  G  G  G+ G  G  G  G  GP G 
Sbjct: 1817 QGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGE 1876

Query: 2236 AGPPGLIGEQGISG------PRGSG-----GAAGAPGERGRTGPLGRKGEPGEPGPKGGI 2284
             G PG++G QG  G      P G G     G  G  G+RG TG  G +G PGE G +G  
Sbjct: 1877 RGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEP 1936

Query: 2285 GN---------------------------------------RGPRGETGDDGRDG----V 2301
            G+                                       RGP+G++G+ G  G    +
Sbjct: 1937 GSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPI 1996

Query: 2302 GSEGRRGKKGERGFPGYPGPKG----------------NPGEPGLNGT---------TGP 2336
            G  G RG KG+RG PG  GP G                 PG+PG+ G           G 
Sbjct: 1997 GFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGR 2056

Query: 2337 KGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSI 2374
             G RG RG  G  G  G+ G PG PG  GP G  G  +
Sbjct: 2057 PGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKV 2094



 Score =  241 bits (614), Expect = 1e-62
 Identities = 159/411 (38%), Positives = 186/411 (45%), Gaps = 73/411 (17%)

Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQ 2090
            G+P K +G+RG RG  G  GP G  G+ G  G  G  G PG  GP G  G  G  G PG+
Sbjct: 1649 GLPGK-AGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGR 1707

Query: 2091 RGVKGSRGFPG--EKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER 2148
                G    PG  EKGE G+ G +G  G  GD GLPG+ GE+G  G RG  GP+G+ G R
Sbjct: 1708 LVDTG----PGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVR 1763

Query: 2149 GDVGIRGDPGNPGQDSQE--------RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGF 2200
            G  G +GD G PG D +          GP G  G  G  G PGRDG+PG  GE G  G  
Sbjct: 1764 GPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPS 1823

Query: 2201 GRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAP 2260
            G  G PG  G  G PG  G  GE G  G  G  G  G  G  G +G  GP+G  GA G  
Sbjct: 1824 GPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGIL 1883

Query: 2261 GERGRTGPLGRKGEPGE--PGPKGGIGNRGPRGETGDDGRDGVGSE-------------- 2304
            G +G  G  G  G PG+  PG  GG G +G RGETG  G  G+  E              
Sbjct: 1884 GPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVD 1943

Query: 2305 -----------------------------------GRRGKKGERGFPGYPGPKGNPGEPG 2329
                                               G +G  GE+G PG  GP G PGE G
Sbjct: 1944 RLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERG 2003

Query: 2330 LNGTTGPKGIR-------GRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDS 2373
            L G  G  G +       G RG  GP G+ G+ G PG PG  G  G  G++
Sbjct: 2004 LKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEA 2054



 Score =  236 bits (602), Expect = 3e-61
 Identities = 148/338 (43%), Positives = 167/338 (49%), Gaps = 47/338 (13%)

Query: 2051 PKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPG---EKGEVG 2107
            PKG  GE G  G  G  G PG+ G PG  G  G QG PG    KG RGFPG     G  G
Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPG 1311

Query: 2108 EIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQER 2167
              G  G  G  G KG PG  G +G+PG RG +GP+GE G  G V     PG PG+   + 
Sbjct: 1312 RAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKG-DP 1370

Query: 2168 GPKGETGDLGPMGVPGRDGVPGGPGET--GKNGGFGRRGPPGAKGNKGGPGQPGFEGEQG 2225
            GP G  G  GP+G PG  G PG PG    G  G  G RGPPG       PG+PG  G   
Sbjct: 1371 GPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPG--- 1427

Query: 2226 TRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIG 2285
              G+ GP GP GPPG  GE+G S      GA G PG+ G  G  G +G PG  GPKG  G
Sbjct: 1428 LPGSPGPQGPVGPPGKKGEKGDS----EDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRG 1483

Query: 2286 NRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGN 2345
              GP GE G+              KGERG PG  G +G PG  G  G  GP+G       
Sbjct: 1484 FPGPLGEAGE--------------KGERGPPGPAGSRGLPGVAGRPGAKGPEG------- 1522

Query: 2346 SGPPGIV---GQKGDPGYPGP--------AGPKGNRGD 2372
              PPG     G+KG+PG PG         AGPKG +GD
Sbjct: 1523 --PPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGD 1558



 Score =  234 bits (598), Expect = 8e-61
 Identities = 144/367 (39%), Positives = 174/367 (47%), Gaps = 66/367 (17%)

Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPG--------ERGPPG 2077
            E+   G P    G+ G  GP+G  GP G  G  G  G  GD+G PG        ERG PG
Sbjct: 2423 ERGLAGPP----GREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPG 2478

Query: 2078 VNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDK----GLPGSSGEKGNP 2133
            + G  G  G  G RG+ G  G  GE+GE G++G  GL G+ GD     G PG  G KG+ 
Sbjct: 2479 IRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDM 2538

Query: 2134 GRRG------DKGPRGEKGERGD------------------------------VGIRGDP 2157
            G RG      DKGPRG+ G+ GD                               GI GDP
Sbjct: 2539 GERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDP 2598

Query: 2158 GNPGQDSQE--RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKG---NK 2212
            G+PG+D     RG KG+ G +GP G+ G  GV G  G  G+ G  G  GPPG  G   +K
Sbjct: 2599 GSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHK 2658

Query: 2213 GGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRK 2272
            G  G+PG  G+ G  G +G  GP G  G  G+ G  G +G  G  G PG  G  GP G  
Sbjct: 2659 GEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGND 2718

Query: 2273 GEPGEPGPKGGIGNRGPRGETGDDGRDGVGSE---------GRRGKKGERGFPGYPGPKG 2323
            G  G PGP G +G RGP G  G  G  G   E         G  G++GE+G PG  GP+G
Sbjct: 2719 GSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRG 2778

Query: 2324 NPGEPGL 2330
              GE  L
Sbjct: 2779 EKGEAAL 2785



 Score =  207 bits (526), Expect = 2e-52
 Identities = 137/319 (42%), Positives = 162/319 (50%), Gaps = 39/319 (12%)

Query: 2038 GQRGDRGPIGSIGPKGIPGED----GYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGV 2093
            G+RG++G +GS G KG  G+     G  G  G +G  GERGP G++G +G +G  G  G 
Sbjct: 2502 GERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGD 2561

Query: 2094 KGSRGFPGEKGEVGEIGLDGLDGEDGDKGL------PGSSGEKGNPGRRGDKG------P 2141
            KGS+G PG+KG  G  GL GL G  G  G       PGS G+ G PG RG+KG      P
Sbjct: 2562 KGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGP 2621

Query: 2142 RGEKGERGDVGIRGDPGNPGQDSQERGPKGETG------DLGPMGVPGRDGVPGGPGETG 2195
            RG KGERG  G  G  G  G D  E GP G  G      ++G  GVPG+ G PG  G  G
Sbjct: 2622 RGLKGERGVKGACGLDGEKG-DKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIG 2680

Query: 2196 KNG--GF-GRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRG 2252
              G  GF G+ GP G +G KG  G PG  G  G  G  G AGP GPPG +G +G  G +G
Sbjct: 2681 PKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQG 2740

Query: 2253 SGGAAGAPGER-----GRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSE--- 2304
              G  G PGER     G  G  G +GE G PGP G  G +G    T DD R  V  E   
Sbjct: 2741 QKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIRGFVRQEMSQ 2800

Query: 2305 -----GRRGKKGERGFPGY 2318
                 G+    G R  P Y
Sbjct: 2801 HCACQGQFIASGSRPLPSY 2819



 Score =  180 bits (457), Expect = 2e-44
 Identities = 110/250 (44%), Positives = 130/250 (52%), Gaps = 33/250 (13%)

Query: 2141 PRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGF 2200
            P+G+KGE G++G+RG  G PG                  G+PGR G PG  G  G     
Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDP----------------GLPGRTGAPGPQGPPGSATAK 1295

Query: 2201 GRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAP 2260
            G RG PGA G    PG PG  G  GT GA G  G  G PG  G+ G  GPRG  G  GAP
Sbjct: 1296 GERGFPGADGR---PGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAP 1352

Query: 2261 GER-GRTGP--LGRKGEPGE---PGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERG 2314
            G+  G  GP   GRKG+PG    PGP+G +G+ GPRG  G  G    G +G RG++G  G
Sbjct: 1353 GQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPG 1412

Query: 2315 ------FPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNS--GPPGIVGQKGDPGYPGPAGP 2366
                   PG PG  G PG PG  G  GP G +G +G+S  G PG+ GQ G PG  GP GP
Sbjct: 1413 PGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGP 1472

Query: 2367 KGNRGDSIDQ 2376
             G  G   D+
Sbjct: 1473 PGAIGPKGDR 1482



 Score =  109 bits (273), Expect = 4e-23
 Identities = 94/331 (28%), Positives = 153/331 (46%), Gaps = 23/331 (6%)

Query: 9   LVAVFCL-FLSGFPTTHAQ-QQQADVKNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVV 66
           LVA  C   L+  P   AQ +++       AADI+FL+D S +IG  +F+ VR FL  +V
Sbjct: 6   LVAALCAGILAEAPRVRAQHRERVTCTRLYAADIVFLLDGSSSIGRSNFREVRSFLEGLV 65

Query: 67  K--SLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEY 124
              S A       FA VQ++ +P TEF L+   +  +V+  I  +SY GG  +TG  + +
Sbjct: 66  LPFSGAASAQGVRFATVQYSDDPRTEFGLDALGSGGDVIRAIRELSYKGGNTRTGAAILH 125

Query: 125 IMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDADEGA 184
           +            A  GVP+V +++TDG S+D +   +  LK   V +FA+G+++AD   
Sbjct: 126 VADHVFLPQL---ARPGVPKVCILITDGKSQDLVDTAAQRLKGQGVKLFAVGIKNADPEE 182

Query: 185 LKEIASEPLNMHMFNLENFT---SLHDIVGNLVSCVHSSVSPERAGD--TETLKDITAQD 239
           LK +AS+P +   F + +F+   +L  +V   V      V   R  D  T   +D+   +
Sbjct: 183 LKRVASQPTSDFFFFVNDFSILRTLLPLVSRRVCTTAGGVPVTRPPDDSTSAPRDLVLSE 242

Query: 240 SADIIFLIDGSNNTGSV-NFAVILDFLVNLLEKLPIGTQQIRV----------GVVQFSD 288
            +     +  +  +G V  + V    L  L + LP   Q++ V          G+   ++
Sbjct: 243 PSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLRGLRPLTE 302

Query: 289 EPRTMFSLDTYSTKAQVLGAVKALGFAGGEL 319
              T+ +L   S    V G  +     G EL
Sbjct: 303 YQVTVIALYANSIGEAVSGTARTTALEGPEL 333



 Score = 99.4 bits (246), Expect = 5e-20
 Identities = 66/198 (33%), Positives = 107/198 (54%), Gaps = 12/198 (6%)

Query: 639 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD--IGNDNIRVGLVQFSDTPVTEFSLNTY 696
           DI+FLLDGS+++G++NF  VR F+  LV           +R   VQ+SD P TEF L+  
Sbjct: 38  DIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDAL 97

Query: 697 QTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSE 756
            +  D++  +R+L  +GG+   TG+A+ +V  + F        R  VP++ +L+T G+S+
Sbjct: 98  GSGGDVIRAIRELSYKGGN-TRTGAAILHVADHVFLP---QLARPGVPKVCILITDGKSQ 153

Query: 757 DSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPS--LVYLMDDFSSLPALPQQLIQ 814
           D    AA  L   G+  F VG   A+  EL+++A  P+    + ++DFS L  L   + +
Sbjct: 154 DLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLPLVSR 213

Query: 815 PLTTYVSGGVEEVPLAQP 832
            + T   G    VP+ +P
Sbjct: 214 RVCTTAGG----VPVTRP 227



 Score = 95.1 bits (235), Expect = 1e-18
 Identities = 78/222 (35%), Positives = 113/222 (50%), Gaps = 16/222 (7%)

Query: 1233 DVVFLIDGSQSAG-PEFQYVRTLIERLVDYLD--VGFDTTRVAVIQFSDDPKVEFLLNAH 1289
            D+VFL+DGS S G   F+ VR+ +E LV            R A +Q+SDDP+ EF L+A 
Sbjct: 38   DIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDAL 97

Query: 1290 SSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSD 1349
             S  +V  A++ L  KGG     G A+ +V+ ++F   L      GVP+  +LI+ GKS 
Sbjct: 98   GSGGDVIRAIRELSYKGG-NTRTGAAILHVADHVF---LPQLARPGVPKVCILITDGKSQ 153

Query: 1350 DEVDDPAVELKQFGVAPFTIA-RNADQEELVKISLSP--EYVFSVSTFRELPSLEQKLLT 1406
            D VD  A  LK  GV  F +  +NAD EEL +++  P  ++ F V+ F  L +L   +  
Sbjct: 154  DLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLPLVSR 213

Query: 1407 PITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVR 1448
             + T         +  TR PP    S   D+V    SS+ +R
Sbjct: 214  RVCTTAGG-----VPVTR-PPDDSTSAPRDLVLSEPSSQSLR 249



 Score = 92.8 bits (229), Expect = 5e-18
 Identities = 59/164 (35%), Positives = 91/164 (55%), Gaps = 10/164 (6%)

Query: 1638 ADIVFLLDGSINFRRDSFQEVLRFVSEIV--DTVYEDGDSIQVGLVQYNSDPTDEFFLKD 1695
            ADIVFLLDGS +  R +F+EV  F+  +V   +       ++   VQY+ DP  EF L  
Sbjct: 37   ADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDA 96

Query: 1696 FSTKRQIIDAINKVVYKGGRHANTKVG--LEHLRVNHFVPEAGSRLDQRVPQIAFVITGG 1753
              +   +I AI ++ YKGG   NT+ G  + H+  + F+P+        VP++  +IT G
Sbjct: 97   LGSGGDVIRAIRELSYKGG---NTRTGAAILHVADHVFLPQLAR---PGVPKVCILITDG 150

Query: 1754 KSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAF 1797
            KS +     +  L  +GVK+FAVG++N D EE+ ++AS   + F
Sbjct: 151  KSQDLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDF 194



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 69/205 (33%), Positives = 98/205 (47%), Gaps = 13/205 (6%)

Query: 1434 AADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSK--VRVGVVQFSNDVFPEFYLK 1491
            AADIVFL+D S  +    F  +R F+  +V   +   S   VR   VQ+S+D   EF L 
Sbjct: 36   AADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLD 95

Query: 1492 TYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGK 1551
               S   V+ AIR L  +GG+   TG A+  VA ++F+         GVP+  +L+  GK
Sbjct: 96   ALGSGGDVIRAIRELSYKGGNT-RTGAAILHVADHVFLPQLA---RPGVPKVCILITDGK 151

Query: 1552 SQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPR--LVFTVREF----RELPNI 1605
            SQD V   AQ ++  G+    VG +N D  EL+ + + P     F V +F      LP +
Sbjct: 152  SQDLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLPLV 211

Query: 1606 EERIMNSFGPSAATPAPPGVDTPPP 1630
              R+  + G    T  PP   T  P
Sbjct: 212  SRRVCTTAGGVPVT-RPPDDSTSAP 235



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 55/154 (35%), Positives = 86/154 (55%), Gaps = 6/154 (3%)

Query: 445 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDL--IQVAVAQYADTVRPEFYFNTH 502
           DIVFL+DGSS++G +NF  +R F+  ++           ++ A  QY+D  R EF  +  
Sbjct: 38  DIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDAL 97

Query: 503 PTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSL 562
            +  +VI A+R++    G+   TG+A+  V +++F       A  G+PK+ +LIT GKS 
Sbjct: 98  GSGGDVIRAIRELSYKGGNTR-TGAAILHVADHVFLPQL---ARPGVPKVCILITDGKSQ 153

Query: 563 DEISQPAQELKRSSIMAFAIGNKGADQAELEEIA 596
           D +   AQ LK   +  FA+G K AD  EL+ +A
Sbjct: 154 DLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVA 187



 Score = 88.6 bits (218), Expect = 9e-17
 Identities = 73/220 (33%), Positives = 109/220 (49%), Gaps = 15/220 (6%)

Query: 1029 DVVFLLDGSEGV-RSGFPLLKEFVQRVVESLD--VGQDRVRVAVVQYSDRTRPEFYLNSY 1085
            D+VFLLDGS  + RS F  ++ F++ +V           VR A VQYSD  R EF L++ 
Sbjct: 38   DIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDAL 97

Query: 1086 MNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSG 1145
             +  DV+ A+R+L+  GG T  TGAA+  V  ++ +         GVP++ I++T  +S 
Sbjct: 98   GSGGDVIRAIRELSYKGGNT-RTGAAILHVADHVFLPQLA---RPGVPKVCILITDGKSQ 153

Query: 1146 DDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIP--DFAVAIPTFRQLGTVQQVISE 1203
            D V   +  +K  G     +GI NAD  E++ ++  P  DF   +  F  L T+  ++S 
Sbjct: 154  DLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLPLVSR 213

Query: 1204 RVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQS 1243
            RV            PV +P P       RD+V     SQS
Sbjct: 214  RVCTTAGG-----VPVTRP-PDDSTSAPRDLVLSEPSSQS 247



 Score = 86.3 bits (212), Expect = 4e-16
 Identities = 69/223 (30%), Positives = 103/223 (46%), Gaps = 16/223 (7%)

Query: 240 SADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIG----TQQIRVGVVQFSDEPRTMFS 295
           +ADI+FL+DGS++ G  NF  +  FL  L+  LP       Q +R   VQ+SD+PRT F 
Sbjct: 36  AADIVFLLDGSSSIGRSNFREVRSFLEGLV--LPFSGAASAQGVRFATVQYSDDPRTEFG 93

Query: 296 LDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISA 355
           LD   +   V+ A++ L + GG     G A+  V ++ F          GVP+V +LI+ 
Sbjct: 94  LDALGSGGDVIRAIRELSYKGGN-TRTGAAILHVADHVFLP---QLARPGVPKVCILITD 149

Query: 356 GPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATD--DNLVFTVPEFRSFGDLQE 413
           G S D +      LK   V  F +G + A   EL+ +A+    +  F V +F     L  
Sbjct: 150 GKSQDLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLP 209

Query: 414 KLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSAL 456
            +   +   A    V +PP   T       RD+V     S +L
Sbjct: 210 LVSRRVCTTAGGVPVTRPPDDSTSA----PRDLVLSEPSSQSL 248



 Score = 77.0 bits (188), Expect = 3e-13
 Identities = 60/216 (27%), Positives = 95/216 (43%), Gaps = 15/216 (6%)

Query: 837  DILFLFDGSANLV-GQFPVVRDFLYKIIDELN--VKPEGTRIAVAQYSDDVKVESRFDEH 893
            DI+FL DGS+++    F  VR FL  ++   +     +G R A  QYSDD + E   D  
Sbjct: 38   DIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDAL 97

Query: 894  QSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSS 953
             S  +++  ++ +  K G     G A+ +   ++F+         GV +  +L+  G+S 
Sbjct: 98   GSGGDVIRAIRELSYKGGNT-RTGAAILHVADHVFLPQLA---RPGVPKVCILITDGKSQ 153

Query: 954  DRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPA--FILAAESLPKIGDLHPQIVN 1011
            D VD  A  LK  GV  F    KNADP EL+++   P   F         +  L P +  
Sbjct: 154  DLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLPLVSR 213

Query: 1012 LLKSVHNGAPA------PVSGEKDVVFLLDGSEGVR 1041
             + +   G P         S  +D+V     S+ +R
Sbjct: 214  RVCTTAGGVPVTRPPDDSTSAPRDLVLSEPSSQSLR 249



 Score = 70.1 bits (170), Expect = 3e-11
 Identities = 33/86 (38%), Positives = 52/86 (60%), Gaps = 4/86 (4%)

Query: 3083 PPQPARSASSSTINLMVSTEPLALTETDI-CKLPKDEGTCRDFILKWYYDP---NTKSCA 3138
            PP+    +  S  ++    +P A  ++D  C LP DEG+C  + L+WY+     +T++C 
Sbjct: 2846 PPEDDEYSEYSEYSVEEYQDPEAPWDSDDPCSLPLDEGSCTAYTLRWYHRAVTGSTEACH 2905

Query: 3139 RFWYGGCGGNENKFGSQKECEKVCAP 3164
             F YGGCGGN N+FG+++ CE+ C P
Sbjct: 2906 PFVYGGCGGNANRFGTREACERRCPP 2931



 Score = 48.5 bits (114), Expect = 1e-04
 Identities = 46/205 (22%), Positives = 88/205 (42%), Gaps = 3/205 (1%)

Query: 1021 PAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLD-VGQDRVRVAVVQYSDRTRPE 1079
            P    G  DVVFL   ++         +  ++R+V +L  +G   V+V ++ YS R  P 
Sbjct: 1046 PVCPRGLADVVFLPHATQDNAHRAEATRRVLERLVLALGPLGPQAVQVGLLSYSHRPSPL 1105

Query: 1080 FYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVL 1139
            F LN   +   ++  +R +  +     N G A+    R +L   A  R  + VP ++++L
Sbjct: 1106 FPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHRYMLAPDAPGR-RQHVPGVMVLL 1164

Query: 1140 TADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQ 1199
              +    D+ +P    +  G   + +G+  AD  +++ ++   D            ++ Q
Sbjct: 1165 VDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLAPGMDSVQTFFAVDDGPSLDQ 1224

Query: 1200 VISERVTQLTREELSRLQPVLQPLP 1224
             +S   T L +   +  QP  +P P
Sbjct: 1225 AVSGLATALCQASFT-TQPRPEPCP 1248



 Score = 42.4 bits (98), Expect = 0.007
 Identities = 43/187 (22%), Positives = 80/187 (42%), Gaps = 11/187 (5%)

Query: 1428 PAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRL-----NIGPSKVRVGVVQFSN 1482
            P      AD+VFL  +++       AH  +   R++ RL      +GP  V+VG++ +S+
Sbjct: 1046 PVCPRGLADVVFLPHATQDN-----AHRAEATRRVLERLVLALGPLGPQAVQVGLLSYSH 1100

Query: 1483 DVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQ 1542
               P F L        +L  IR +     S  N G A+    R +    A  R    VP 
Sbjct: 1101 RPSPLFPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHRYMLAPDAPGR-RQHVPG 1159

Query: 1543 HLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFREL 1602
             +VL++    + D+    +  ++SG+  + +G    D  +L+ +      V T     + 
Sbjct: 1160 VMVLLVDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLAPGMDSVQTFFAVDDG 1219

Query: 1603 PNIEERI 1609
            P++++ +
Sbjct: 1220 PSLDQAV 1226



 Score = 40.0 bits (92), Expect = 0.037
 Identities = 58/229 (25%), Positives = 94/229 (41%), Gaps = 26/229 (11%)

Query: 1202 SERVTQLTR--EELSRLQPVLQPLPSPGVG---------GKRDVVFLIDGSQSAGPEFQY 1250
            S+RVT L      +  L PVL  +  P            G  DVVFL   +Q      + 
Sbjct: 1012 SQRVTGLEPGVSYIFSLTPVLDGVRGPEASVTQTPVCPRGLADVVFLPHATQDNAHRAEA 1071

Query: 1251 VRTLIERLVDYL-DVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLR------ 1303
             R ++ERLV  L  +G    +V ++ +S  P   F LN      ++   +QR+R      
Sbjct: 1072 TRRVLERLVLALGPLGPQAVQVGLLSYSHRPSPLFPLN---GSHDLGIILQRIRDMPYMD 1128

Query: 1304 PKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFG 1363
            P G    N+G A+    R +       R  + VP  +VL+       ++  P  E +  G
Sbjct: 1129 PSGN---NLGTAVVTAHRYMLAPDAPGR-RQHVPGVMVLLVDEPLRGDIFSPIREAQASG 1184

Query: 1364 VAPFTIA-RNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTL 1411
            +    +    AD E+L +++   + V +     + PSL+Q +    T L
Sbjct: 1185 LNVVMLGMAGADPEQLRRLAPGMDSVQTFFAVDDGPSLDQAVSGLATAL 1233



 Score = 39.3 bits (90), Expect = 0.063
 Identities = 47/198 (23%), Positives = 83/198 (41%), Gaps = 21/198 (10%)

Query: 2603 RPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFA 2662
            R   R+R         D+ F+LD + +     F E++ ++  LV     +    AS    
Sbjct: 22   RAQHRERVTCTRLYAADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGA----ASAQGV 77

Query: 2663 RVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYT 2722
            R A VQ++             + EF L   GS   ++  + R ++   G    G+AI + 
Sbjct: 78   RFATVQYSDDP----------RTEFGLDALGSGGDVIRAI-RELSYKGGNTRTGAAILHV 126

Query: 2723 IENVF-ESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIK 2781
             ++VF      P   K+ +L+  G+  +     AQR+    K +G     +GI +  + +
Sbjct: 127  ADHVFLPQLARPGVPKVCILITDGKSQDLVDTAAQRL----KGQGVKLFAVGI-KNADPE 181

Query: 2782 EVYTFASEPNDVFFKLVD 2799
            E+   AS+P   FF  V+
Sbjct: 182  ELKRVASQPTSDFFFFVN 199



 Score = 37.4 bits (85), Expect = 0.24
 Identities = 59/292 (20%), Positives = 114/292 (39%), Gaps = 29/292 (9%)

Query: 121  GLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDA 180
            GLE   Q  +  +    AG+G    +   T+        +PS EL+  D ++ ++ +   
Sbjct: 923  GLEPATQYRVRLSVLGPAGEGPSAEVTARTESPR-----VPSIELRVVDTSIDSVTLAWT 977

Query: 181  D--------------EGALKEIASEPLNMH-MFNLENFTSLHDIVGNLVSC--VHSSVSP 223
                            G  +E+   P  +  + + +  T L   V  + S   V   V  
Sbjct: 978  PVSRASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPVLDGVRG 1037

Query: 224  ERAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAV--ILDFLVNLLEKLPIGTQQIRV 281
              A  T+T   +  +  AD++FL   + +      A   +L+ LV  L   P+G Q ++V
Sbjct: 1038 PEASVTQT--PVCPRGLADVVFLPHATQDNAHRAEATRRVLERLVLALG--PLGPQAVQV 1093

Query: 282  GVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSR 341
            G++ +S  P  +F L+       +L  ++ + +      N+G A+      +        
Sbjct: 1094 GLLSYSHRPSPLFPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAV-VTAHRYMLAPDAPG 1152

Query: 342  VEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIA 393
              + VP V+VL+   P   +I   +   + + +    LG   A   +L+ +A
Sbjct: 1153 RRQHVPGVMVLLVDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLA 1204



 Score = 33.5 bits (75), Expect = 3.4
 Identities = 36/164 (21%), Positives = 64/164 (39%), Gaps = 3/164 (1%)

Query: 824  VEEVPLAQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELN-VKPEGTRIAVAQYSD 882
            V + P+  P    D++FL   + +   +    R  L +++  L  + P+  ++ +  YS 
Sbjct: 1042 VTQTPVC-PRGLADVVFLPHATQDNAHRAEATRRVLERLVLALGPLGPQAVQVGLLSYSH 1100

Query: 883  DVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQ 942
                    +       IL  ++ M        NLG A+  A RY+    A  R    V  
Sbjct: 1101 RPSPLFPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHRYMLAPDAPGR-RQHVPG 1159

Query: 943  FLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQI 986
             +VLLV       +  P    + SG+   +     ADP +L ++
Sbjct: 1160 VMVLLVDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRL 1203


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score =  274 bits (701), Expect = 9e-73
 Identities = 159/361 (44%), Positives = 187/361 (51%), Gaps = 31/361 (8%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPG------ERGPPGVNGTQGFQGCPGQR 2091
            GQRG+ GP G  G  G PG  G  G+PG  G PG      ERG  G+ G +G  G PGQ 
Sbjct: 1030 GQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQP 1089

Query: 2092 GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGR---RGDKGPRGEKGER 2148
            G  G+ G PG  G  GE G  G  GE G+ G PGS G  G PG    RG++GP+G  GE+
Sbjct: 1090 GYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEK 1149

Query: 2149 GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208
            GD G +G PG PG      GP G  G +G  G PG     G  G  G +G  G  GPPG 
Sbjct: 1150 GDQGFQGQPGFPGPP----GPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGP 1205

Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2268
             G +G  G  G +G+ G  G +G  GPAGPPGL+G  G  G  G  G  G  G+ G+ GP
Sbjct: 1206 PGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGP 1265

Query: 2269 LGRKGEPG------------EPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGF- 2315
             G  G PG             PGP G +G  GP G+ G  G   VG +G RG  GERG  
Sbjct: 1266 PGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLA 1325

Query: 2316 --PGYPGPKGN---PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNR 2370
              PG PGP G+   PGEPG +G  G +G  G++G  GPPG  G  G  G  G AG KG  
Sbjct: 1326 GLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRA 1385

Query: 2371 G 2371
            G
Sbjct: 1386 G 1386



 Score =  257 bits (656), Expect = 1e-67
 Identities = 152/359 (42%), Positives = 175/359 (48%), Gaps = 26/359 (7%)

Query: 2037 SGQRGDRGPIG------SIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQ 2090
            +G +G+ GP G      + GP G+PG  G RGY G  G  GE GPPG  G  G  G  G 
Sbjct: 1077 TGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGP 1136

Query: 2091 RGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD 2150
            RG +G +G  GEKG+ G  G  G  G  G  G PG  G  G PG + +KG  G +G  G 
Sbjct: 1137 RGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGL 1196

Query: 2151 VGIRGDPGNPG------------QDSQE--RGPKGETGDLGPMGVPGRDGVPGGPGETGK 2196
             G  G PG PG            +D +   RG  G  G  G MG PG  G  G PG  G 
Sbjct: 1197 PGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGP 1256

Query: 2197 NGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGIS-----GPR 2251
             G  G+ GPPG+ G  G  G+PG  G QG  G  G  GP GPPG  G  GIS     G R
Sbjct: 1257 KGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDR 1316

Query: 2252 GSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKK 2310
            G+ G  G  G  G+ GP G  G PGEPG  G  G  GP G+ G  G  G  G  G  G+K
Sbjct: 1317 GATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQK 1376

Query: 2311 GERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGN 2369
            G+ G  G  G  G PG+ G  G  GP G  G RG+ G PG  G  G PG PG  G   N
Sbjct: 1377 GQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVN 1435



 Score =  255 bits (651), Expect = 6e-67
 Identities = 158/352 (44%), Positives = 182/352 (51%), Gaps = 46/352 (13%)

Query: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEG--GP-GERGPPGVNGT---QGFQGCPGQR 2091
            G +G+RG  GS G KG PG  G  G PG  G  GP GERGP G +G    QGFQG PG  
Sbjct: 1102 GIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFP 1161

Query: 2092 GVKGSRGFPGEKGEVGEIGLD---GLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER 2148
            G  G  GFPG+ G  G  G     G +G  G  GLPGS G  G PG +G  G  G  G+ 
Sbjct: 1162 GPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKD 1221

Query: 2149 GDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGA 2208
            G  G+RGDP          GP G  G +GP G  G+ G PG P   G  G  G+ GPPG+
Sbjct: 1222 GKPGLRGDP----------GPAGPPGLMGPPGFKGKTGHPGLP---GPKGDCGKPGPPGS 1268

Query: 2209 KGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGP 2268
             G  G  G+PG  G QG  G  G  GP GPPG  G  GIS       A G  G+RG TG 
Sbjct: 1269 TGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGIS-------AVGLKGDRGATGE 1321

Query: 2269 LGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEP 2328
             G  G PG+PGP    G+ GP GE G D     G+ G+ G  G++GF G PGPKG+PG  
Sbjct: 1322 RGLAGLPGQPGPP---GHPGPPGEPGTD-----GAAGKEGPPGKQGFYGPPGPKGDPGAA 1373

Query: 2329 GLNGTTGPKGIRGRRGNS---------GPPGIVGQKGDPGYPGPAGPKGNRG 2371
            G  G  G KG  G  G           GPPG  G++G PG PGP+G  G  G
Sbjct: 1374 GQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPG 1425



 Score =  250 bits (638), Expect = 2e-65
 Identities = 156/364 (42%), Positives = 181/364 (49%), Gaps = 37/364 (10%)

Query: 2041 GDRGPIGSIG---PKGIPGEDGYRGYPGDEGGPGERGP---PGVNGTQGFQGCPGQRGVK 2094
            GD G +GS G   P G+PG+ G  G PG  G PG  GP   PG  G  G  G PG +G +
Sbjct: 1012 GDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGER 1071

Query: 2095 GSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIR 2154
            G  G  G+KGE G  G  G  G  G  GLPG  GE+G  G  G+KG   E G  G  G+ 
Sbjct: 1072 GLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKG---EPGPPGSEGLP 1128

Query: 2155 GDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGG 2214
            G PG P     ERGP+G +G+ G  G  G+ G PG PG  G  G  G  GPPG +  KG 
Sbjct: 1129 GPPG-PAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGS 1187

Query: 2215 PGQPGFEGEQGTRGAQGPAG---PAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGR 2271
             G  G  G  G+ G  GP G   PAG  GL G+ G  G RG  G AG PG  G  G  G+
Sbjct: 1188 EGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGK 1247

Query: 2272 KGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKGERGFPGYPGPKGNP----- 2325
             G PG PGPKG  G  GP G TG  G +G  G+ G +G+ G  G  G PGP G P     
Sbjct: 1248 TGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGI 1307

Query: 2326 ------------GE---PGLNGTTGPKGIRGRRGNSGPPGIVGQKGDP---GYPGPAGPK 2367
                        GE    GL G  GP G  G  G  G  G  G++G P   G+ GP GPK
Sbjct: 1308 SAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPK 1367

Query: 2368 GNRG 2371
            G+ G
Sbjct: 1368 GDPG 1371



 Score =  243 bits (620), Expect = 2e-63
 Identities = 163/409 (39%), Positives = 192/409 (46%), Gaps = 74/409 (18%)

Query: 2026 EKACCGVPCKCSGQRGDRGPIGSIGPK--GIPGEDGYRGYPGDEGGPGERGPPGVNGTQG 2083
            EK   G P    G +G  GP+G  G    G PG DG +G  G  G PGE+GP G  G  G
Sbjct: 819  EKGAQGSP----GVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPG 874

Query: 2084 -----------FQGCPG----------QRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKG 2122
                       F G PG          Q G +G  G PG  G  G  GL G+ G +G  G
Sbjct: 875  ECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPG 934

Query: 2123 LPGSSGEKGN----------------PGRRGDKGPRGEKGERGDVGIRGDPGNPGQDS-- 2164
             PG + E G+                 G+R   G   EKGE+GD GI   PG PG D+  
Sbjct: 935  QPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGI---PGVPGLDNCA 991

Query: 2165 ------------QERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRG-------- 2204
                        + RG   E GD G +G PG  G PG PG+ G+ G  G RG        
Sbjct: 992  QCFLSLERPRAEEARGDNSE-GDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPI 1050

Query: 2205 -PPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGER 2263
             PPG  G  G PG PG +GE+G  G  G  G  GPPG  G  G +GP    G  G  GER
Sbjct: 1051 GPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGP---PGLPGIKGER 1107

Query: 2264 GRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPK 2322
            G TG  G KGEPG PG +G  G  GP G  G+ G  G  G +G +G +G+ GFPG PGP 
Sbjct: 1108 GYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPP 1167

Query: 2323 GNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
            G PG+ G  G  GP+  +G  G  GP G+ G  G PG PG  GP G  G
Sbjct: 1168 GFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDG 1216



 Score =  243 bits (620), Expect = 2e-63
 Identities = 163/441 (36%), Positives = 196/441 (44%), Gaps = 107/441 (24%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPG------ERGPPGVNGTQGFQGCPGQ 2090
            +G RG+RGP G+ G KG  G  G  G+PG  G PG        GPPG    +G +G  G 
Sbjct: 1134 AGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGP 1193

Query: 2091 RGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGD 2150
             G+ GS G PG  G  G  GLDGLDG+DG  GL G  G  G PG  G  G +G+ G  G 
Sbjct: 1194 SGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGL 1253

Query: 2151 VGIRGDPGNPGQDSQ--ERGPKGETGDLGPMG---VPGRDGVPGGPGE------------ 2193
             G +GD G PG        G +GE G +GP G    PG  G PG PG+            
Sbjct: 1254 PGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLK 1313

Query: 2194 -----TGKNGGFGRRGPPGAKGNKGGPGQPGF------EGEQGTRGAQGPAGPAGPPGLI 2242
                 TG+ G  G  G PG  G+ G PG+PG       EG  G +G  GP GP G PG  
Sbjct: 1314 GDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAA 1373

Query: 2243 GEQGISGPRGSGGAAGAPGERGRTGPLG------RKGEPGEPGPKG-----GI------- 2284
            G++G +G +G  G  G PG+ G  GP+G       +G PG PGP G     G+       
Sbjct: 1374 GQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDM 1433

Query: 2285 ---------------------------------------GNRGPRGETGDDGRDG----- 2300
                                                   G  GP G+ G  GR G     
Sbjct: 1434 VNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSP 1493

Query: 2301 -----VGSEGRRGKKGERGFPGYPGPKGN-----PGEPGLNGTTGPKGIRGRRGNSGPPG 2350
                 +G EGR+G  G RG PG  G KG+      GE GL G  GP+G  G  G  G  G
Sbjct: 1494 GLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGY-GKMGATG 1552

Query: 2351 IVGQKGDPGYPGPAGPKGNRG 2371
             +GQ+G PG PGP GP G  G
Sbjct: 1553 PMGQQGIPGIPGPPGPMGQPG 1573



 Score =  243 bits (619), Expect = 3e-63
 Identities = 165/419 (39%), Positives = 189/419 (45%), Gaps = 85/419 (20%)

Query: 2037 SGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGT--------------- 2081
            S Q G +GP G  GP G PG  G +G PG+ G PG+ G     G+               
Sbjct: 900  SWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDC 959

Query: 2082 -QGFQGCPG---QRGVKGSRGFPGEKG-----------------------EVGEIGLDGL 2114
             QG +  PG   ++G KG +G PG  G                         G+ G  G 
Sbjct: 960  VQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGS 1019

Query: 2115 DGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETG 2174
             G  G  GLPG  GE+G PG RG  GP G  G  G  G  G PG PG    ERG  G TG
Sbjct: 1020 PGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQG-ERGLTGLTG 1078

Query: 2175 DLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAG 2234
            D G  G PG+ G PG  G  G  G  G RG  G+ G KG PG PG EG  G  G  GP G
Sbjct: 1079 DKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRG 1138

Query: 2235 PAGPPGLIGEQGISGPRGSGGAAGAPG------------------ERGRTGPLGRKGEPG 2276
              GP G  GE+G  G +G  G  G PG                  E+G  G  G  G PG
Sbjct: 1139 ERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPG 1198

Query: 2277 EPGPKGGIGNRGPRGETGDDGRDGV-------------GSEGRRGKKGERGFPGYPGPKG 2323
             PGP G  G +GP G  G DG+DG              G  G  G KG+ G PG PGPKG
Sbjct: 1199 SPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKG 1258

Query: 2324 NPGEPGLNGTTGPKGIRGR------RGNSGPPGIVGQKGDPGYPGPA-----GPKGNRG 2371
            + G+PG  G+TG  G  G       +G  GPPG VG  G PG PGPA     G KG+RG
Sbjct: 1259 DCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRG 1317



 Score =  239 bits (609), Expect = 4e-62
 Identities = 154/387 (39%), Positives = 172/387 (44%), Gaps = 55/387 (14%)

Query: 2033 PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRG 2092
            P    G  G  GP G  G +G  G  G +G  G +G PG  GPPG  G  G  G PG  G
Sbjct: 1121 PPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPG 1180

Query: 2093 ---VKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERG 2149
                KGS G  G  G  G  G  G  G  G  GL G  G+ G PG RGD GP G  G  G
Sbjct: 1181 PQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMG 1240

Query: 2150 DVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAK 2209
              G +G  G+PG      GPKG+ G  GP   PG  G PG  GE G  G  GR GPPG  
Sbjct: 1241 PPGFKGKTGHPGLP----GPKGDCGKPGP---PGSTGRPGAEGEPGAMGPQGRPGPPGHV 1293

Query: 2210 GNKGGPGQP-----------GFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAG 2258
            G  G PGQP           G  G  G RG  G  G  GPPG  G  G  G  G+ G  G
Sbjct: 1294 GPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEG 1353

Query: 2259 APGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPG 2317
             PG++G  GP G KG+PG  G KG  G +G  G  G  G+ G +G  G  G  GERG PG
Sbjct: 1354 PPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPG 1413

Query: 2318 YPGPKGNPGEPGLNGTTG---------------------------------PKGIRGRRG 2344
             PGP G+PG PG+ G+ G                                 P  +    G
Sbjct: 1414 APGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPG 1473

Query: 2345 NSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
              GPPG  G  G PG PG  G  G  G
Sbjct: 1474 RPGPPGKDGAPGRPGAPGSPGLPGQIG 1500



 Score =  236 bits (602), Expect = 3e-61
 Identities = 162/407 (39%), Positives = 180/407 (44%), Gaps = 75/407 (18%)

Query: 2025 AEKACCGV--PCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQ 2082
            AEK   G+  P    G  G  GP G  GP G+ G DG  G PG  G PG  GPPG+ G  
Sbjct: 1183 AEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPP 1242

Query: 2083 GFQGC---PGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDK 2139
            GF+G    PG  G KG  G PG  G  G  G +G  G  G +G PG  G  G PG  G  
Sbjct: 1243 GFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQP 1302

Query: 2140 GPRGE-----KGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGET 2194
            GP G      KG+RG  G RG  G PGQ        G  G  GP G PG DG  G  G  
Sbjct: 1303 GPAGISAVGLKGDRGATGERGLAGLPGQP-------GPPGHPGPPGEPGTDGAAGKEGPP 1355

Query: 2195 GKNGGFGRRGP---PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQG---IS 2248
            GK G +G  GP   PGA G KG  G+ G  G  G  G  G  GP GPPG  GE+G     
Sbjct: 1356 GKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAP 1415

Query: 2249 GPRGSGGAAGAPGERG------------------------------------------RT 2266
            GP GS G  G PG  G                                          R 
Sbjct: 1416 GPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRP 1475

Query: 2267 GPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGV-GSEGRRGKKG--------ERGFPG 2317
            GP G+ G PG PG  G  G  G  G  G  G  GV G  G +G+KG        E G PG
Sbjct: 1476 GPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPG 1535

Query: 2318 YPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPA 2364
             PGP+G PG  G  G TGP G +G  G  GPPG +GQ G  G+  P+
Sbjct: 1536 PPGPQGPPGY-GKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPS 1581



 Score =  233 bits (594), Expect = 2e-60
 Identities = 164/455 (36%), Positives = 192/455 (42%), Gaps = 110/455 (24%)

Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGI--PGEDGYRGYPGDEGGPG------ERGPPGVNGTQ 2082
            G     +G+ G  GP G  GP+G+  PG+ G  G PG +G PG      E GPPG  G Q
Sbjct: 732  GTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPG-RGVQ 790

Query: 2083 GFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGL--------------PGSSG 2128
            G QG PG  G+ G +G PG +G  G  G  G  G  G KG               PG  G
Sbjct: 791  GPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDG 850

Query: 2129 EKGNPGRRG---DKGPRGEKGE--------RGDVGIRGDPGNPGQ---DSQERGPKGETG 2174
            ++G  G RG   +KGPRGEKGE        +GD+   G PG PG     S + GP+G  G
Sbjct: 851  QQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPG 910

Query: 2175 DLGP---------MGVPGRDGVPGGP---------------------------------- 2191
              GP          GVPG +G+PG P                                  
Sbjct: 911  IPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYL 970

Query: 2192 ---GETGKNG--------------------------GFGRRGPPGAKGNKGGPGQPGFEG 2222
               GE G  G                          G    G PG  G+ G PG PG  G
Sbjct: 971  VEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPG 1030

Query: 2223 EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKG 2282
            ++G  G  G  G  GPPG IG  G  G  GS G  G  GERG TG  G KGEPG PG  G
Sbjct: 1031 QRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPG 1090

Query: 2283 GIGNRGPRGETGDDGRDG-VGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRG 2341
              G  GP G  G  G  G  GS G +G+ G  G  G PGP G  G  G  G  G  G +G
Sbjct: 1091 YPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKG 1150

Query: 2342 RRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQ 2376
             +G  G PG  G  G PG+PG  G  G  G   ++
Sbjct: 1151 DQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEK 1185



 Score =  233 bits (593), Expect = 3e-60
 Identities = 156/391 (39%), Positives = 193/391 (49%), Gaps = 60/391 (15%)

Query: 2033 PCKCS-GQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQR 2091
            P +C+ G +G++G  G++GP G+PG  G +G  G++G  G +G PG  G  G    PG+ 
Sbjct: 369  PLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGR---PGEI 425

Query: 2092 GVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKG-PRGEKGERGD 2150
             V G +G   +KG+ G +G +GL GE G  GLPG  G  G PG  GD G P G KG++G 
Sbjct: 426  CVIGPKG---QKGDPGFVGPEGLAGEPGPPGLPGPPGI-GLPGTPGDPGGPPGPKGDKGS 481

Query: 2151 VGIRGDPGNPGQDSQERGPKGETGD------LGPMGVPGRDGVPGGPGETGKNGG-FGRR 2203
             GI G  G PG    + G KGE GD        P G     G+PG PG  G+ G     R
Sbjct: 482  SGIPGKEG-PGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPAR 540

Query: 2204 GPPGAKGNKGGPGQP-----------------GFEGEQGTRG--AQGPAGPAGPPGLIGE 2244
            G PG +G KG  G+P                 G  G+ G+ G    G  G AG PGL GE
Sbjct: 541  GDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGE 600

Query: 2245 QGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGG---------IGNRGPRGETGD 2295
            +G  G  G  G+ G PG  G  G  G KGEP EP P            +   GP GE G+
Sbjct: 601  KGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGE 660

Query: 2296 DGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
             G  G G  G++GK GERG  G  G  GNPG+PG  GTTG  G+ G  G  GP G  G+K
Sbjct: 661  PGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEK 720

Query: 2356 GD---------------PGYPGPAGPKGNRG 2371
            GD                G PG  GPKG +G
Sbjct: 721  GDGCTACPSLQGTVTDMAGRPGQPGPKGEQG 751



 Score =  224 bits (571), Expect = 1e-57
 Identities = 154/391 (39%), Positives = 181/391 (46%), Gaps = 62/391 (15%)

Query: 2031 GVPC-KCSGQRGDRGPIGSIGPKGIPGEDGYR--GYPGDEGGPGERGPPGVNGTQGFQGC 2087
            G PC  CS   G +  + S G  G  G  G+   G PG  G PG +G  G  G  G  G 
Sbjct: 553  GEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGS 612

Query: 2088 PGQRGVKGSRGFPGEKGEV------------GEIGLDGLDGEDGDKGLPGSSGEKGNPGR 2135
            PG  G  G  G  G KGE             G++ +  L G  G+KG PG  G  G PG+
Sbjct: 613  PGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGF-GLPGK 671

Query: 2136 RGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDG--------- 2186
            +G  G RG KG++GD G  GDPG PG   +  G  GE G  GP G  G  G         
Sbjct: 672  QGKAGERGLKGQKGDAGNPGDPGTPGTTGRP-GLSGEPGVQGPAGPKGEKGDGCTACPSL 730

Query: 2187 ---VPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIG 2243
               V    G  G+ G  G +GP G  G  G PGQPG  G QG  G +G  G  GPPG   
Sbjct: 731  QGTVTDMAGRPGQPGPKGEQGPEGV-GRPGKPGQPGLPGVQGPPGLKGVQGEPGPPG--- 786

Query: 2244 EQGISGPRGSGGA------AGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGE--TGD 2295
             +G+ GP+G  GA       G PG RG  GP G KG  G PG KG  G  GP G   +G 
Sbjct: 787  -RGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGP 845

Query: 2296 DGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPG-----------LNGTTGPKGI----R 2340
             GRD     G++G+ G RG PG  GP+G  GEPG            +G  G  G+     
Sbjct: 846  PGRD-----GQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSS 900

Query: 2341 GRRGNSGPPGIVGQKGDPGYPGPAGPKGNRG 2371
             + G  GPPGI G  G PG PG  G  GN G
Sbjct: 901  WQPGPQGPPGIPGPPGPPGVPGLQGVPGNNG 931



 Score =  221 bits (564), Expect = 7e-57
 Identities = 159/410 (38%), Positives = 186/410 (45%), Gaps = 69/410 (16%)

Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGV------NGTQGF 2084
            G+P       G  GP G  G  GIPG++G  G PG  G  GE+G P         G Q F
Sbjct: 461  GLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNF 520

Query: 2085 QGCPGQRGVKGSRGFP-------------GEKGE--------VGEIGLDGLDGEDGDKGL 2123
             G PG+ G KG  G P             GEKGE        VG   L    G  GD G 
Sbjct: 521  VGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGS 580

Query: 2124 PGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE--RGPKGET-------- 2173
            PG  G  G PGR G  G +GEKG  G+ G  G PG PG       +G KGE         
Sbjct: 581  PGF-GLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALS 639

Query: 2174 ----GDL------GPMGVPGRDGVPGG--PGETGKNGGFGRRGPPGAKGNKGGPGQPGFE 2221
                GD+      GP G  G  G PG   PG+ GK G  G +G  G  GN G PG PG  
Sbjct: 640  NLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTT 699

Query: 2222 GEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSG------GAAGAPGERGRTGP--LGRKG 2273
            G  G  G  G  GPAGP G  G+   + P   G      G  G PG +G  GP  +GR G
Sbjct: 700  GRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPG 759

Query: 2274 EPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGY---PGPKGNPGEPGL 2330
            +PG+PG  G  G  G +G  G+ G  G G +G +G+ G  G PG    PGP+G PG  G 
Sbjct: 760  KPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGE 819

Query: 2331 NGTTGPKGIRGRRGN--------SGPPGIVGQKGDPGYPGPAGPKGNRGD 2372
             G  G  G++G  G         SGPPG  GQ+G  G  G  G KG RG+
Sbjct: 820  KGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGE 869



 Score =  220 bits (561), Expect = 2e-56
 Identities = 164/437 (37%), Positives = 197/437 (45%), Gaps = 98/437 (22%)

Query: 2031 GVPCKCSGQRGDRGPIGSIGPKGIPGEDGY---RGYPGDEGGPGERGPPGVN--GTQGFQ 2085
            GVP K  G+ G  G I  IGPKG  G+ G+    G  G+ G PG  GPPG+   GT G  
Sbjct: 411  GVPGK-PGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDP 469

Query: 2086 GCP-GQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDK---------------GLPGSSGE 2129
            G P G +G KGS G PG++G  G+ G  G+ GE GD                GLPG  G 
Sbjct: 470  GGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGP 529

Query: 2130 KGNPG----RRGDKGPRGEKGERGD-----------------VGIRGDPGNPGQDSQ--- 2165
            KG PG     RGD G +G KGE+G+                  G  GD G+PG       
Sbjct: 530  KGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLP 589

Query: 2166 -ERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPP------------------ 2206
               G  G  G+ G  G  G  G PG PG  G  G  G +G P                  
Sbjct: 590  GRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVV 649

Query: 2207 ---GAKGNKGGPGQPGF-----EGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAG 2258
               G  G KG PG PGF     +G+ G RG +G  G AG PG   + G  G  G  G +G
Sbjct: 650  ALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPG---DPGTPGTTGRPGLSG 706

Query: 2259 APGERGRTGPLGRKGE------------------PGEPGPKGGIGNRGPRGETGDDGRDG 2300
             PG +G  GP G KG+                  PG+PGPKG  G  G  G  G  G+ G
Sbjct: 707  EPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGV-GRPGKPGQPG 765

Query: 2301 V-GSEGRRGKKGERGFPGYPGP--KGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGD 2357
            + G +G  G KG +G PG PG   +G  GEPG  G  G +G+ G RG  GP G  G +G 
Sbjct: 766  LPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGS 825

Query: 2358 PGYPGPAGPKGNRGDSI 2374
            PG  G  GP G  G S+
Sbjct: 826  PGVKGATGPVGPPGASV 842



 Score =  142 bits (358), Expect = 5e-33
 Identities = 105/306 (34%), Positives = 121/306 (39%), Gaps = 74/306 (24%)

Query: 2038 GQRGDRG--PIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKG 2095
            GQ G  G   +G  G +G  GE G  G PG  G PG  GPPG  GT G  G  G  G +G
Sbjct: 1300 GQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQG 1359

Query: 2096 SRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRG 2155
              G PG KG+ G  G  G  GE G  G+PG  G+ G+ G  G  GP GE+G  G  G  G
Sbjct: 1360 FYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSG 1419

Query: 2156 DPGNPG----------QDSQER----------------------------------GPKG 2171
             PG PG           D  +R                                  GP G
Sbjct: 1420 SPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPG 1479

Query: 2172 ETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQG 2231
            + G  G  G PG  G+PG  G  G+ G  G RG PG KG KG  G  G  GE G  G  G
Sbjct: 1480 KDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGI-GIAGENGLPGPPG 1538

Query: 2232 PAGPAG--------------------PPGLIGEQGISGPRGSGGAAGA-------PGERG 2264
            P GP G                    PPG +G+ G +G        GA       P  + 
Sbjct: 1539 PQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKT 1598

Query: 2265 RTGPLG 2270
              GP G
Sbjct: 1599 MKGPFG 1604



 Score =  139 bits (351), Expect = 3e-32
 Identities = 98/280 (35%), Positives = 122/280 (43%), Gaps = 55/280 (19%)

Query: 2156 DPGNPGQDSQERG---PKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNK 2212
            +P N   D+Q  G    K E G          +  P   G    N      GP G KG +
Sbjct: 283  EPQNSEVDAQLTGRISQKAERGAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGER 342

Query: 2213 GGPGQPGFEGEQGTRG--------------AQGP---------AGPAGPPGLIGEQGISG 2249
            G PG PG +GE+G RG              A+GP          GP+G PG  GE+G  G
Sbjct: 343  GLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKG 402

Query: 2250 PRGSGGAAGAPGERGR---------TGPLGRKGEPGEPGPKGGIGNRGPRGETGDDG--- 2297
             +G GG  G PG+ GR          GP G+KG+PG  GP+G  G  GP G  G  G   
Sbjct: 403  EKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGL 462

Query: 2298 ----RDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTG---------PKGIRGRRG 2344
                 D  G  G +G KG  G PG  GP G PG+PG+ G  G         P+G +   G
Sbjct: 463  PGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVG 522

Query: 2345 NSGPPGIVGQKGDP----GYPGPAGPKGNRGDSIDQCALI 2380
              G PG  G+ GDP    G PG  G KG +G+    C+ +
Sbjct: 523  LPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSV 562


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.136    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 128,395,349
Number of Sequences: 37866
Number of extensions: 6858436
Number of successful extensions: 144218
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 375
Number of HSP's successfully gapped in prelim test: 1016
Number of HSP's that attempted gapping in prelim test: 29393
Number of HSP's gapped (non-prelim): 16921
length of query: 3177
length of database: 18,247,518
effective HSP length: 121
effective length of query: 3056
effective length of database: 13,665,732
effective search space: 41762476992
effective search space used: 41762476992
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 72 (32.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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