Guide to the Human Genome
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Search of human proteins with 4507583

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507583 tumor necrosis factor receptor superfamily, member 6
isoform 1 precursor [Homo sapiens]
         (335 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507583 tumor necrosis factor receptor superfamily, member 6 ...   699   0.0  
gi|23510421 tumor necrosis factor receptor superfamily, member 6...   642   0.0  
gi|23510423 tumor necrosis factor receptor superfamily, member 6...   472   e-133
gi|21361086 tumor necrosis factor receptor superfamily, member 1...    72   5e-13
gi|224494019 tumor necrosis factor receptor superfamily, member ...    69   8e-12
gi|23200041 tumor necrosis factor receptor superfamily, member 1...    68   1e-11
gi|4505039 lymphotoxin beta receptor [Homo sapiens]                    68   1e-11
gi|224494026 tumor necrosis factor receptor superfamily, member ...    67   2e-11
gi|23200023 tumor necrosis factor receptor superfamily, member 2...    65   7e-11
gi|23200021 tumor necrosis factor receptor superfamily, member 2...    65   7e-11
gi|89142745 tumor necrosis factor receptor superfamily, member 2...    65   7e-11
gi|4507569 tumor necrosis factor receptor superfamily, member 25...    65   7e-11
gi|4507587 tumor necrosis factor receptor superfamily, member 7 ...    65   1e-10
gi|22547108 tumor necrosis factor receptor superfamily, member 1...    64   2e-10
gi|22547121 tumor necrosis factor receptor superfamily, member 1...    63   3e-10
gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]             63   4e-10
gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]            63   4e-10
gi|148743793 osteoprotegerin precursor [Homo sapiens]                  59   6e-09
gi|4507577 tumor necrosis factor receptor 2 precursor [Homo sapi...    55   9e-08
gi|4505393 nerve growth factor receptor precursor [Homo sapiens]       55   1e-07
gi|4507565 tumor necrosis factor receptor superfamily, member 11...    54   3e-07
gi|14790170 tumor necrosis factor receptor superfamily, member 6...    53   4e-07
gi|4507585 tumor necrosis factor receptor superfamily, member 6b...    53   4e-07
gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapi...    49   8e-06
gi|4507579 tumor necrosis factor receptor superfamily, member 4 ...    47   3e-05
gi|68348711 tumor necrosis factor receptor superfamily, member 8...    40   0.002
gi|23200025 tumor necrosis factor receptor superfamily, member 2...    37   0.025
gi|61743980 stabilin 2 precursor [Homo sapiens]                        37   0.032
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]       35   0.072
gi|5730095 tumor necrosis factor receptor superfamily, member 9 ...    35   0.072

>gi|4507583 tumor necrosis factor receptor superfamily, member 6
           isoform 1 precursor [Homo sapiens]
          Length = 335

 Score =  699 bits (1804), Expect = 0.0
 Identities = 335/335 (100%), Positives = 335/335 (100%)

Query: 1   MLGIWTLLPLVLTSVARLSSKSVNAQVTDINSKGLELRKTVTTVETQNLEGLHHDGQFCH 60
           MLGIWTLLPLVLTSVARLSSKSVNAQVTDINSKGLELRKTVTTVETQNLEGLHHDGQFCH
Sbjct: 1   MLGIWTLLPLVLTSVARLSSKSVNAQVTDINSKGLELRKTVTTVETQNLEGLHHDGQFCH 60

Query: 61  KPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCT 120
           KPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCT
Sbjct: 61  KPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCT 120

Query: 121 RTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSNTKCKEEGSRSNLGWLCLL 180
           RTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSNTKCKEEGSRSNLGWLCLL
Sbjct: 121 RTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSNTKCKEEGSRSNLGWLCLL 180

Query: 181 LLPIPLIVWVKRKEVQKTCRKHRKENQGSHESPTLNPETVAINLSDVDLSKYITTIAGVM 240
           LLPIPLIVWVKRKEVQKTCRKHRKENQGSHESPTLNPETVAINLSDVDLSKYITTIAGVM
Sbjct: 181 LLPIPLIVWVKRKEVQKTCRKHRKENQGSHESPTLNPETVAINLSDVDLSKYITTIAGVM 240

Query: 241 TLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGKKEAYDTLIKDLKK 300
           TLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGKKEAYDTLIKDLKK
Sbjct: 241 TLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGKKEAYDTLIKDLKK 300

Query: 301 ANLCTLAEKIQTIILKDITSDSENSNFRNEIQSLV 335
           ANLCTLAEKIQTIILKDITSDSENSNFRNEIQSLV
Sbjct: 301 ANLCTLAEKIQTIILKDITSDSENSNFRNEIQSLV 335


>gi|23510421 tumor necrosis factor receptor superfamily, member 6
           isoform 2 precursor [Homo sapiens]
          Length = 314

 Score =  642 bits (1656), Expect = 0.0
 Identities = 314/335 (93%), Positives = 314/335 (93%), Gaps = 21/335 (6%)

Query: 1   MLGIWTLLPLVLTSVARLSSKSVNAQVTDINSKGLELRKTVTTVETQNLEGLHHDGQFCH 60
           MLGIWTLLPLVLTSVARLSSKSVNAQVTDINSKGLELRKTVTTVETQNLEGLHHDGQFCH
Sbjct: 1   MLGIWTLLPLVLTSVARLSSKSVNAQVTDINSKGLELRKTVTTVETQNLEGLHHDGQFCH 60

Query: 61  KPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCT 120
           KPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCT
Sbjct: 61  KPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCT 120

Query: 121 RTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSNTKCKEEGSRSNLGWLCLL 180
           RTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSNTKCKEE            
Sbjct: 121 RTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSNTKCKEE------------ 168

Query: 181 LLPIPLIVWVKRKEVQKTCRKHRKENQGSHESPTLNPETVAINLSDVDLSKYITTIAGVM 240
                    VKRKEVQKTCRKHRKENQGSHESPTLNPETVAINLSDVDLSKYITTIAGVM
Sbjct: 169 ---------VKRKEVQKTCRKHRKENQGSHESPTLNPETVAINLSDVDLSKYITTIAGVM 219

Query: 241 TLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGKKEAYDTLIKDLKK 300
           TLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGKKEAYDTLIKDLKK
Sbjct: 220 TLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGKKEAYDTLIKDLKK 279

Query: 301 ANLCTLAEKIQTIILKDITSDSENSNFRNEIQSLV 335
           ANLCTLAEKIQTIILKDITSDSENSNFRNEIQSLV
Sbjct: 280 ANLCTLAEKIQTIILKDITSDSENSNFRNEIQSLV 314


>gi|23510423 tumor necrosis factor receptor superfamily, member 6
           isoform 3 precursor [Homo sapiens]
          Length = 220

 Score =  472 bits (1215), Expect = e-133
 Identities = 217/217 (100%), Positives = 217/217 (100%)

Query: 1   MLGIWTLLPLVLTSVARLSSKSVNAQVTDINSKGLELRKTVTTVETQNLEGLHHDGQFCH 60
           MLGIWTLLPLVLTSVARLSSKSVNAQVTDINSKGLELRKTVTTVETQNLEGLHHDGQFCH
Sbjct: 1   MLGIWTLLPLVLTSVARLSSKSVNAQVTDINSKGLELRKTVTTVETQNLEGLHHDGQFCH 60

Query: 61  KPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCT 120
           KPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCT
Sbjct: 61  KPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCT 120

Query: 121 RTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSNTKCKEEGSRSNLGWLCLL 180
           RTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSNTKCKEEGSRSNLGWLCLL
Sbjct: 121 RTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSNTKCKEEGSRSNLGWLCLL 180

Query: 181 LLPIPLIVWVKRKEVQKTCRKHRKENQGSHESPTLNP 217
           LLPIPLIVWVKRKEVQKTCRKHRKENQGSHESPTLNP
Sbjct: 181 LLPIPLIVWVKRKEVQKTCRKHRKENQGSHESPTLNP 217


>gi|21361086 tumor necrosis factor receptor superfamily, member 10a
           [Homo sapiens]
          Length = 468

 Score = 72.4 bits (176), Expect = 5e-13
 Identities = 46/142 (32%), Positives = 70/142 (49%), Gaps = 19/142 (13%)

Query: 57  QFCHKP----CPPGERKARDCTVNGDEPD-CVPCQEGKEYTDKAHFSSKCRRCRLCDEGH 111
           Q+ H P    CPPG  ++       + P  C  C EG  YT+ ++    C  C  C    
Sbjct: 122 QWEHSPLGELCPPGSHRS-------EHPGACNRCTEGVGYTNASNNLFACLPCTACKSDE 174

Query: 112 GLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTK-CEHGI--IKECTLTSNTKC--K 166
             E    CT T+NT C+CKP  F N    E C  C++ C  G+  +K+CT  S+ +C  K
Sbjct: 175 --EERSPCTTTRNTACQCKPGTFRNDNSAEMCRKCSRGCPRGMVKVKDCTPWSDIECVHK 232

Query: 167 EEGSRSNLGWLCLLLLPIPLIV 188
           E G+  N+  + ++ L +PL++
Sbjct: 233 ESGNGHNIWVILVVTLVVPLLL 254


>gi|224494019 tumor necrosis factor receptor superfamily, member 10b
           isoform 1 precursor [Homo sapiens]
          Length = 440

 Score = 68.6 bits (166), Expect = 8e-12
 Identities = 41/115 (35%), Positives = 61/115 (53%), Gaps = 15/115 (13%)

Query: 63  CPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEIN-CTR 121
           CPPG        ++ D  DC+ C+ G++Y+   +    C RC  CD G   EVE++ CT 
Sbjct: 81  CPPGHH------ISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSG---EVELSPCTT 131

Query: 122 TQNTKCRCKPNFFCNSTVCEHCDPC-TKCEHGIIK--ECTLTSNTKC--KEEGSR 171
           T+NT C+C+   F      E C  C T C  G++K  +CT  S+ +C  KE G++
Sbjct: 132 TRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKESGTK 186


>gi|23200041 tumor necrosis factor receptor superfamily, member 14
           precursor [Homo sapiens]
          Length = 283

 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 57/234 (24%), Positives = 88/234 (37%), Gaps = 56/234 (23%)

Query: 56  GQFCHKPCPPGERKARDC-TVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLE 114
           G  C   C PG R    C  + G    C PC  G  Y    +  SKC +C++CD   GL 
Sbjct: 50  GSECCPKCSPGYRVKEACGELTGTV--CEPCPPGT-YIAHLNGLSKCLQCQMCDPAMGLR 106

Query: 115 VEINCTRTQNTKCRCKPNFFC------------------------------NSTVCEHCD 144
              NC+RT+N  C C P  FC                                T+C++C 
Sbjct: 107 ASRNCSRTENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCP 166

Query: 145 PCTKCEHGIIKECTLTSNTKC-----KEEGSRSNLGW----------LCLLLLPIPLIVW 189
           P T   +G ++EC     TKC     K     S+  W          + ++   + LI+ 
Sbjct: 167 PGTFSPNGTLEEC--QHQTKCSWLVTKAGAGTSSSHWVWWFLSGSLVIVIVCSTVGLIIC 224

Query: 190 VKRKE-----VQKTCRKHRKENQGSHESPTLNPETVAINLSDVDLSKYITTIAG 238
           VKR++     V+      RK  +   E+  +       +++ V + + I +  G
Sbjct: 225 VKRRKPRGDVVKVIVSVQRKRQEAEGEATVIEALQAPPDVTTVAVEETIPSFTG 278


>gi|4505039 lymphotoxin beta receptor [Homo sapiens]
          Length = 435

 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 40/131 (30%), Positives = 59/131 (45%), Gaps = 8/131 (6%)

Query: 43  TVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCR 102
           T   Q  E      + C   CPPG   +  C+   D   C  C E   Y +  ++ + C+
Sbjct: 42  TCRDQEKEYYEPQHRICCSRCPPGTYVSAKCSRIRDTV-CATCAENS-YNEHWNYLTICQ 99

Query: 103 RCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSN 162
            CR CD   GLE    CT  + T+CRC+P  FC +   E    CT CE  ++ +C   + 
Sbjct: 100 LCRPCDPVMGLEEIAPCTSKRKTQCRCQPGMFCAAWALE----CTHCE--LLSDCPPGTE 153

Query: 163 TKCKEEGSRSN 173
            + K+E  + N
Sbjct: 154 AELKDEVGKGN 164



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 19/66 (28%), Positives = 28/66 (42%), Gaps = 2/66 (3%)

Query: 63  CPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCTRT 122
           CPPG        V      CVPC+ G  + + +  S++C+    C E  GL      T  
Sbjct: 148 CPPGTEAELKDEVGKGNNHCVPCKAG-HFQNTSSPSARCQPHTRC-ENQGLVEAAPGTAQ 205

Query: 123 QNTKCR 128
            +T C+
Sbjct: 206 SDTTCK 211


>gi|224494026 tumor necrosis factor receptor superfamily, member 10b
           isoform 2 precursor [Homo sapiens]
          Length = 411

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 41/113 (36%), Positives = 59/113 (52%), Gaps = 15/113 (13%)

Query: 63  CPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEIN-CTR 121
           CPPG        ++ D  DC+ C+ G++Y+   +    C RC  CD G   EVE++ CT 
Sbjct: 81  CPPGHH------ISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSG---EVELSPCTT 131

Query: 122 TQNTKCRCKPNFFCNSTVCEHCDPC-TKCEHGIIK--ECTLTSNTKC--KEEG 169
           T+NT C+C+   F      E C  C T C  G++K  +CT  S+ +C  KE G
Sbjct: 132 TRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKESG 184


>gi|23200023 tumor necrosis factor receptor superfamily, member 25
           isoform 3 precursor [Homo sapiens]
          Length = 380

 Score = 65.5 bits (158), Expect = 7e-11
 Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 7/101 (6%)

Query: 56  GQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEV 115
           G FC + CP G      CT       C+ C +      + H +S+C RC+ CDE      
Sbjct: 44  GLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVA 103

Query: 116 EINCTRTQNTKCRCKPNFF-------CNSTVCEHCDPCTKC 149
             NC+   +T+C CKP +F       C S+   +C PC  C
Sbjct: 104 LENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDC 144


>gi|23200021 tumor necrosis factor receptor superfamily, member 25
           isoform 1 precursor [Homo sapiens]
          Length = 426

 Score = 65.5 bits (158), Expect = 7e-11
 Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 7/101 (6%)

Query: 56  GQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEV 115
           G FC + CP G      CT       C+ C +      + H +S+C RC+ CDE      
Sbjct: 44  GLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVA 103

Query: 116 EINCTRTQNTKCRCKPNFF-------CNSTVCEHCDPCTKC 149
             NC+   +T+C CKP +F       C S+   +C PC  C
Sbjct: 104 LENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDC 144


>gi|89142745 tumor necrosis factor receptor superfamily, member 25
           isoform 12 precursor [Homo sapiens]
          Length = 181

 Score = 65.5 bits (158), Expect = 7e-11
 Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 7/101 (6%)

Query: 56  GQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEV 115
           G FC + CP G      CT       C+ C +      + H +S+C RC+ CDE      
Sbjct: 44  GLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVA 103

Query: 116 EINCTRTQNTKCRCKPNFF-------CNSTVCEHCDPCTKC 149
             NC+   +T+C CKP +F       C S+   +C PC  C
Sbjct: 104 LENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDC 144


>gi|4507569 tumor necrosis factor receptor superfamily, member 25
           isoform 2 precursor [Homo sapiens]
          Length = 417

 Score = 65.5 bits (158), Expect = 7e-11
 Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 7/101 (6%)

Query: 56  GQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEV 115
           G FC + CP G      CT       C+ C +      + H +S+C RC+ CDE      
Sbjct: 44  GLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVA 103

Query: 116 EINCTRTQNTKCRCKPNFF-------CNSTVCEHCDPCTKC 149
             NC+   +T+C CKP +F       C S+   +C PC  C
Sbjct: 104 LENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDC 144


>gi|4507587 tumor necrosis factor receptor superfamily, member 7
           precursor [Homo sapiens]
          Length = 260

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 29/90 (32%), Positives = 40/90 (44%), Gaps = 3/90 (3%)

Query: 56  GQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEV 115
           G+ C + C PG    +DC  +     C PC  G  ++   H    C  CR C+ G  +  
Sbjct: 36  GKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCNSGLLVR- 94

Query: 116 EINCTRTQNTKCRCKPNFFCNSTVCEHCDP 145
             NCT T N +C C+  + C    C  CDP
Sbjct: 95  --NCTITANAECACRNGWQCRDKECTECDP 122


>gi|22547108 tumor necrosis factor receptor superfamily, member 10d
           precursor [Homo sapiens]
          Length = 386

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 37/116 (31%), Positives = 55/116 (47%), Gaps = 11/116 (9%)

Query: 63  CPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCTRT 122
           CP G  ++           C PC EG +YT  ++    C  C +C  G     + +CT T
Sbjct: 83  CPAGSHRSEYTGA------CNPCTEGVDYTIASNNLPSCLLCTVCKSGQ--TNKSSCTTT 134

Query: 123 QNTKCRCKPNFFCNSTVCEHCDPC-TKCEHGIIK--ECTLTSNTKCKEEGSRSNLG 175
           ++T C+C+   F +    E C  C T C  G++K   CT  S+ KCK E + S+ G
Sbjct: 135 RDTVCQCEKGSFQDKNSPEMCRTCRTGCPRGMVKVSNCTPRSDIKCKNESAASSTG 190


>gi|22547121 tumor necrosis factor receptor superfamily, member 10c
           precursor [Homo sapiens]
          Length = 259

 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 35/115 (30%), Positives = 55/115 (47%), Gaps = 14/115 (12%)

Query: 58  FCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLC--DEGHGLEV 115
           F  + CP G  ++           C PC EG +YT+ ++    C  C +C  D+ H    
Sbjct: 48  FKGEECPAGSHRSEHTGA------CNPCTEGVDYTNASNNEPSCFPCTVCKSDQKH---- 97

Query: 116 EINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIK--ECTLTSNTKCKEE 168
           + +CT T++T C+CK   F N    E C  C++C  G ++   CT   + +C EE
Sbjct: 98  KSSCTMTRDTVCQCKEGTFRNENSPEMCRKCSRCPSGEVQVSNCTSWDDIQCVEE 152


>gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]
          Length = 277

 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 35/110 (31%), Positives = 52/110 (47%), Gaps = 4/110 (3%)

Query: 59  CHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEIN 118
           C   C PG++   DCT    E +C+PC E  E+ D  +  + C + + CD   GL V+  
Sbjct: 37  CCSLCQPGQKLVSDCT-EFTETECLPCGES-EFLDTWNRETHCHQHKYCDPNLGLRVQQK 94

Query: 119 CTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCE--HGIIKECTLTSNTKCK 166
            T   +T C C+  + C S  CE C     C    G+ +  T  S+T C+
Sbjct: 95  GTSETDTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQIATGVSDTICE 144


>gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]
          Length = 203

 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 35/110 (31%), Positives = 52/110 (47%), Gaps = 4/110 (3%)

Query: 59  CHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEIN 118
           C   C PG++   DCT    E +C+PC E  E+ D  +  + C + + CD   GL V+  
Sbjct: 37  CCSLCQPGQKLVSDCT-EFTETECLPCGES-EFLDTWNRETHCHQHKYCDPNLGLRVQQK 94

Query: 119 CTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCE--HGIIKECTLTSNTKCK 166
            T   +T C C+  + C S  CE C     C    G+ +  T  S+T C+
Sbjct: 95  GTSETDTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQIATGVSDTICE 144


>gi|148743793 osteoprotegerin precursor [Homo sapiens]
          Length = 401

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 73/284 (25%), Positives = 107/284 (37%), Gaps = 55/284 (19%)

Query: 42  TTVETQNLEGLHHDGQFCHK----PCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHF 97
           TT ET   + LH+D +  H+     CPPG    + CT    +  C PC +   YTD  H 
Sbjct: 19  TTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKW-KTVCAPCPD-HYYTDSWHT 76

Query: 98  SSKCRRCR-LCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVC---EHCDPCTKCEHGI 153
           S +C  C  +C E   ++ E  C RT N  C CK   +     C     C P      G+
Sbjct: 77  SDECLYCSPVCKELQYVKQE--CNRTHNRVCECKEGRYLEIEFCLKHRSCPP----GFGV 130

Query: 154 IKECTLTSNTKCKE--EGSRSNLGWLCLLLLPIPLIVWVKRKEVQKTCRKH--------- 202
           ++  T   NT CK   +G  SN                      +  CRKH         
Sbjct: 131 VQAGTPERNTVCKRCPDGFFSN------------------ETSSKAPCRKHTNCSVFGLL 172

Query: 203 --RKENQGSHESPTLNPETVAINLSDVDLSKYITTIAGVMT------LSQVKGFVRKNGV 254
             +K N       + N E+      DV L +       V T      LS +   +    V
Sbjct: 173 LTQKGNATHDNICSGNSESTQKCGIDVTLCEEAFFRFAVPTKFTPNWLSVLVDNLPGTKV 232

Query: 255 NEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGKKEAYDTLIKDL 298
           N   ++ IK  +   + EQ  QLL+ W   +  ++    +I+D+
Sbjct: 233 NAESVERIKRQH--SSQEQTFQLLKLWKHQNKDQDIVKKIIQDI 274


>gi|4507577 tumor necrosis factor receptor 2 precursor [Homo
           sapiens]
          Length = 461

 Score = 55.1 bits (131), Expect = 9e-08
 Identities = 35/115 (30%), Positives = 49/115 (42%), Gaps = 8/115 (6%)

Query: 57  QFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVE 116
           Q C   C PG+     CT   D   C  C++   YT   ++  +C  C        +E +
Sbjct: 51  QMCCSKCSPGQHAKVFCTKTSDTV-CDSCEDST-YTQLWNWVPECLSCGSRCSSDQVETQ 108

Query: 117 INCTRTQNTKCRCKPNFFC---NSTVCEHCDPCTKCE--HGIIKECTLTSNTKCK 166
             CTR QN  C C+P ++C       C  C P  KC    G+ +  T TS+  CK
Sbjct: 109 A-CTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCK 162


>gi|4505393 nerve growth factor receptor precursor [Homo sapiens]
          Length = 427

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 10/117 (8%)

Query: 54  HDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGL 113
           H G+ C K C  GE  A+ C  N  +  C PC +   ++D    +  C+ C  C    GL
Sbjct: 39  HSGECC-KACNLGEGVAQPCGAN--QTVCEPCLDSVTFSDVVSATEPCKPCTEC---VGL 92

Query: 114 E-VEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCE--HGIIKECTLTSNTKCKE 167
           + +   C    +  CRC   ++ + T    C+ C  CE   G++  C    NT C+E
Sbjct: 93  QSMSAPCVEADDAVCRCAYGYYQDETT-GRCEACRVCEAGSGLVFSCQDKQNTVCEE 148


>gi|4507565 tumor necrosis factor receptor superfamily, member 11a
           precursor [Homo sapiens]
          Length = 616

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 36/115 (31%), Positives = 51/115 (44%), Gaps = 6/115 (5%)

Query: 54  HDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGL 113
           H G+ C+K C PG+  +  CT   D   C+PC    EY D  +   KC   ++CD G  L
Sbjct: 42  HLGRCCNK-CEPGKYMSSKCTTTSDSV-CLPCGPD-EYLDSWNEEDKCLLHKVCDTGKAL 98

Query: 114 EVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKE--CTLTSNTKCK 166
              +    T   +C C   +   S  CE C   T+C  G+  +    L  +T CK
Sbjct: 99  VAVVAGNSTTPRRCACTAGYHW-SQDCECCRRNTECAPGLGAQHPLQLNKDTVCK 152


>gi|14790170 tumor necrosis factor receptor superfamily, member 6b
           [Homo sapiens]
          Length = 300

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 39/109 (35%), Positives = 50/109 (45%), Gaps = 14/109 (12%)

Query: 63  CPPGERKARDCTVNGDEPD-CVPCQEGKEYTDKAHFSSKCRRCR-LCDEGHGLEVEINCT 120
           CPPG    R C    D P  C PC   + YT   ++  +CR C  LC E    E    C 
Sbjct: 52  CPPGTFVQRPC--RRDSPTTCGPCPP-RHYTQFWNYLERCRYCNVLCGERE--EEARACH 106

Query: 121 RTQNTKCRCKPNFFCNSTVC-EH--CDPCTKCEHGIIKECTLTSNTKCK 166
            T N  CRC+  FF ++  C EH  C P      G+I   T + NT+C+
Sbjct: 107 ATHNRACRCRTGFFAHAGFCLEHASCPPGA----GVIAPGTPSQNTQCQ 151


>gi|4507585 tumor necrosis factor receptor superfamily, member 6b
           [Homo sapiens]
          Length = 300

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 39/109 (35%), Positives = 50/109 (45%), Gaps = 14/109 (12%)

Query: 63  CPPGERKARDCTVNGDEPD-CVPCQEGKEYTDKAHFSSKCRRCR-LCDEGHGLEVEINCT 120
           CPPG    R C    D P  C PC   + YT   ++  +CR C  LC E    E    C 
Sbjct: 52  CPPGTFVQRPC--RRDSPTTCGPCPP-RHYTQFWNYLERCRYCNVLCGERE--EEARACH 106

Query: 121 RTQNTKCRCKPNFFCNSTVC-EH--CDPCTKCEHGIIKECTLTSNTKCK 166
            T N  CRC+  FF ++  C EH  C P      G+I   T + NT+C+
Sbjct: 107 ATHNRACRCRTGFFAHAGFCLEHASCPPGA----GVIAPGTPSQNTQCQ 151


>gi|4507575 tumor necrosis factor receptor 1 precursor [Homo
           sapiens]
          Length = 455

 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 57/222 (25%), Positives = 68/222 (30%), Gaps = 68/222 (30%)

Query: 55  DGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFS-----SKCRR------ 103
           +   C   C  G     DC   G + DC  C+ G     + H       SKCR+      
Sbjct: 54  NNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVE 113

Query: 104 --------------------------------CRLCDEGHGLEVEINCTRTQNTKCRCKP 131
                                           C LC  G    V ++C   QNT C C  
Sbjct: 114 ISSCTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCLNG---TVHLSCQEKQNTVCTCHA 170

Query: 132 NFFCNSTVCEHCDPCTKCEHGIIKECT-----LTSNTKCKEEGSRSNL------GWLCLL 180
            FF     C  C  C K       ECT        N K  E+   + L        LCLL
Sbjct: 171 GFFLRENECVSCSNCKKS-----LECTKLCLPQIENVKGTEDSGTTVLLPLVIFFGLCLL 225

Query: 181 -LLPIPLIV----WVKRKEVQKTCRKHRKENQGSHESPTLNP 217
            LL I L+     W K K     C K   E +G  E  T  P
Sbjct: 226 SLLFIGLMYRYQRW-KSKLYSIVCGKSTPEKEGELEGTTTKP 266



 Score = 29.3 bits (64), Expect = 5.2
 Identities = 18/67 (26%), Positives = 36/67 (53%), Gaps = 1/67 (1%)

Query: 246 KGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGKKEA-YDTLIKDLKKANLC 304
           K FVR+ G+++ +ID ++  N +   E +  +L  W +   ++EA  + L + L+  +L 
Sbjct: 372 KEFVRRLGLSDHEIDRLELQNGRCLREAQYSMLATWRRRTPRREATLELLGRVLRDMDLL 431

Query: 305 TLAEKIQ 311
              E I+
Sbjct: 432 GCLEDIE 438


>gi|4507579 tumor necrosis factor receptor superfamily, member 4
           precursor [Homo sapiens]
          Length = 277

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 7/75 (9%)

Query: 97  FSSKCRRCRLCDEGHGLEVEINCTRTQNTKCR-CKPNFFCNSTVCEHCDPCTKCEHGIIK 155
           + S  R C  C  G+G+     C+R+QNT CR C P F+ +    + C PCT C      
Sbjct: 36  YPSNDRCCHECRPGNGMVSR--CSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGS 93

Query: 156 E----CTLTSNTKCK 166
           E    CT T +T C+
Sbjct: 94  ERKQLCTATQDTVCR 108



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 26/72 (36%), Positives = 33/72 (45%), Gaps = 4/72 (5%)

Query: 59  CHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEIN 118
           CH+ C PG      C+       C PC  G  Y D    S  C+ C  C+   G E +  
Sbjct: 43  CHE-CRPGNGMVSRCS-RSQNTVCRPCGPGF-YNDVVS-SKPCKPCTWCNLRSGSERKQL 98

Query: 119 CTRTQNTKCRCK 130
           CT TQ+T CRC+
Sbjct: 99  CTATQDTVCRCR 110


>gi|68348711 tumor necrosis factor receptor superfamily, member 8
           isoform 1 precursor [Homo sapiens]
          Length = 595

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 30/113 (26%), Positives = 44/113 (38%), Gaps = 11/113 (9%)

Query: 59  CHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEIN 118
           C   CP G    + C       DC    E   Y D+A    +C  C  C     +E +  
Sbjct: 44  CCYRCPMGLFPTQQCPQR--PTDCRKQCEPDYYLDEA---DRCTACVTCSRDDLVE-KTP 97

Query: 119 CTRTQNTKCRCKPNFFCNSTVCEHCDPC---TKCEHGIIKEC--TLTSNTKCK 166
           C    +  C C+P  FC+++    C  C   + C  G+I +   T   NT C+
Sbjct: 98  CAWNSSRVCECRPGMFCSTSAVNSCARCFFHSVCPAGMIVKFPGTAQKNTVCE 150


>gi|23200025 tumor necrosis factor receptor superfamily, member 25
           isoform 4 precursor [Homo sapiens]
          Length = 372

 Score = 37.0 bits (84), Expect = 0.025
 Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 8/53 (15%)

Query: 104 CRLCDEGHGLEVEINCTRTQNTKCRCKPNFF-------CNSTVCEHCDPCTKC 149
           CR C     + +E NC+   +T+C CKP +F       C S+   +C PC  C
Sbjct: 48  CRGCPAASQVALE-NCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDC 99


>gi|61743980 stabilin 2 precursor [Homo sapiens]
          Length = 2551

 Score = 36.6 bits (83), Expect = 0.032
 Identities = 29/135 (21%), Positives = 47/135 (34%), Gaps = 6/135 (4%)

Query: 51   GLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEG 110
            G+H D       C      + +C  N D      C  G  +       +    C + + G
Sbjct: 1424 GVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAG--FQGNGTICTAINACEISNGG 1481

Query: 111  HGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIK--ECTLT--SNTKCK 166
               + +   T      C CK  +  +  VC   +PC +   G  K  ECT T  +   C 
Sbjct: 1482 CSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACN 1541

Query: 167  EEGSRSNLGWLCLLL 181
               + +  G +C L+
Sbjct: 1542 CLPAYTGDGKVCTLI 1556



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 35/140 (25%), Positives = 47/140 (33%), Gaps = 15/140 (10%)

Query: 51  GLHHDGQFCHK--PC----PPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRC 104
           G   DG  C +  PC    P G  +  +C   G       CQ+G  +T      S+   C
Sbjct: 857 GYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQG--WTGNGRDCSEINNC 914

Query: 105 RLCDEGHGLEVEINCTRTQ--NTKCRCKPNFFCNSTVCEHCDPCT----KCEHGIIKECT 158
            L   G G     +C        +C CK  F  N   CE    C     KC      + T
Sbjct: 915 LLPSAG-GCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQST 973

Query: 159 LTSNTKCKEEGSRSNLGWLC 178
            +    C  +      G+LC
Sbjct: 974 SSGVWSCVCQEGYEGDGFLC 993



 Score = 32.0 bits (71), Expect = 0.80
 Identities = 33/128 (25%), Positives = 47/128 (36%), Gaps = 27/128 (21%)

Query: 57  QFCHKPCPPGERKARDCTVNGDEPDCV--PCQEGKEYTDKAHFSSKCR---RCRLCDEGH 111
           QFC  P   G R  + C        CV   C    + +D A  +  CR     RLCD+  
Sbjct: 776 QFCSDPNKYGPRCNKKCL-------CVHGTCNNRID-SDGACLTGTCRDGSAGRLCDKQT 827

Query: 112 GL--------EVEINCTRTQNT-KCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSN 162
                      +   C  +  T  C CK  +  + T+C   DPCT    G       + N
Sbjct: 828 SACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPG-----GCSRN 882

Query: 163 TKCKEEGS 170
            +C + G+
Sbjct: 883 AECIKTGT 890


>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
          Length = 1823

 Score = 35.4 bits (80), Expect = 0.072
 Identities = 34/120 (28%), Positives = 46/120 (38%), Gaps = 22/120 (18%)

Query: 73  CTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRL------------CDEGHGLEVEINCT 120
           C  N   P+C  C  G  Y +     S C++C              CDE  G     NC 
Sbjct: 157 CNENYAGPNCERCAPGY-YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCR--NCL 213

Query: 121 R-TQNTKC-RCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSNTKCKEEGSRSNLGWLC 178
           R T   KC RC P ++ ++ + ++C  C  C  G     T     +C EEG     G  C
Sbjct: 214 RNTTGFKCERCAPGYYGDARIAKNCAVC-NCGGGPCDSVT----GECLEEGFEPPTGMDC 268


>gi|5730095 tumor necrosis factor receptor superfamily, member 9
           precursor [Homo sapiens]
          Length = 255

 Score = 35.4 bits (80), Expect = 0.072
 Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 5/51 (9%)

Query: 119 CTRTQNTKCR-CKPNFFCNSTVCEHCDPCTKCEHGII---KECTLTSNTKC 165
           C   +N  C  C PN F ++     CD C +C+ G+    KEC+ TSN +C
Sbjct: 37  CDNNRNQICSPCPPNSFSSAGGQRTCDICRQCK-GVFRTRKECSSTSNAEC 86



 Score = 35.4 bits (80), Expect = 0.072
 Identities = 16/52 (30%), Positives = 23/52 (44%), Gaps = 3/52 (5%)

Query: 102 RRCRLCDEGHGL-EVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHG 152
           R C +C +  G+      C+ T N +C C P F C    C  C+    C+ G
Sbjct: 60  RTCDICRQCKGVFRTRKECSSTSNAECDCTPGFHCLGAGCSMCE--QDCKQG 109


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,330,475
Number of Sequences: 37866
Number of extensions: 643929
Number of successful extensions: 2202
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 94
Number of HSP's that attempted gapping in prelim test: 2057
Number of HSP's gapped (non-prelim): 223
length of query: 335
length of database: 18,247,518
effective HSP length: 103
effective length of query: 232
effective length of database: 14,347,320
effective search space: 3328578240
effective search space used: 3328578240
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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