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Search of human proteins with 122056617
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens]
(330 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens] 657 0.0
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 592 e-169
gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens] 411 e-115
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 348 5e-96
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens] 162 4e-40
gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens] 119 3e-27
gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens] 117 1e-26
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens] 117 1e-26
gi|13994151 PDZ and LIM domain 1 [Homo sapiens] 117 1e-26
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens] 115 4e-26
gi|166235176 PDZ and LIM domain protein 3 isoform a [Homo sapiens] 114 9e-26
gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens] 114 2e-25
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens] 114 2e-25
gi|19923181 PDZ and LIM domain 4 isoform 1 [Homo sapiens] 108 9e-24
gi|196162711 PDZ and LIM domain 4 isoform 2 [Homo sapiens] 107 1e-23
gi|166235178 PDZ and LIM domain protein 3 isoform b [Homo sapiens] 106 2e-23
gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens] 90 3e-18
gi|28866957 PDZ and LIM domain 2 isoform 1 [Homo sapiens] 90 3e-18
gi|21361888 PDZ and LIM domain 2 isoform 2 [Homo sapiens] 90 3e-18
gi|166706868 synaptopodin 2-like isoform a [Homo sapiens] 72 9e-13
gi|193083191 synaptopodin 2 isoform c [Homo sapiens] 65 1e-10
gi|193083185 synaptopodin 2 isoform b [Homo sapiens] 65 1e-10
gi|193083183 synaptopodin 2 isoform a [Homo sapiens] 65 1e-10
gi|74272284 membrane associated guanylate kinase, WW and PDZ dom... 62 5e-10
gi|27436957 membrane associated guanylate kinase, WW and PDZ dom... 54 1e-07
gi|118600967 shroom family member 4 [Homo sapiens] 50 4e-06
gi|11321640 basic beta 1 syntrophin [Homo sapiens] 50 4e-06
gi|4502175 apical protein of Xenopus-like [Homo sapiens] 50 4e-06
gi|13376349 PDZ domain containing 7 [Homo sapiens] 49 8e-06
gi|155969695 membrane-associated guanylate kinase-related 3 iso... 49 8e-06
>gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens]
Length = 330
Score = 657 bits (1696), Expect = 0.0
Identities = 330/330 (100%), Positives = 330/330 (100%)
Query: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM
Sbjct: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
Query: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP 120
THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP
Sbjct: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP 120
Query: 121 SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL 180
SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL
Sbjct: 121 SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL 180
Query: 181 LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKDLAVD 240
LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKDLAVD
Sbjct: 181 LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKDLAVD 240
Query: 241 SASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSRE 300
SASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSRE
Sbjct: 241 SASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSRE 300
Query: 301 RFETERNSPRFAKLRNWHHGLSAQILNVKS 330
RFETERNSPRFAKLRNWHHGLSAQILNVKS
Sbjct: 301 RFETERNSPRFAKLRNWHHGLSAQILNVKS 330
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 592 bits (1527), Expect = e-169
Identities = 299/303 (98%), Positives = 299/303 (98%)
Query: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM
Sbjct: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
Query: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP 120
THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP
Sbjct: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP 120
Query: 121 SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL 180
SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL
Sbjct: 121 SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL 180
Query: 181 LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKDLAVD 240
LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKDLAVD
Sbjct: 181 LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKDLAVD 240
Query: 241 SASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSRE 300
SASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRS
Sbjct: 241 SASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSST 300
Query: 301 RFE 303
E
Sbjct: 301 PIE 303
Score = 39.3 bits (90), Expect = 0.005
Identities = 30/111 (27%), Positives = 45/111 (40%), Gaps = 6/111 (5%)
Query: 85 RPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAPSPSPEARASPGTPGTPELRPTFSP 144
R + ++ P V P+P + P + + + PSP+P SP TP PT++P
Sbjct: 396 RVVTTASIRPSVYQPVPASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTP 455
Query: 145 AFSRPSAFSSLAEASDPGPPRA-----SLRAKTSPEGARDLLGPKALPGSS 190
+ P+ S A +P P A + A P D K PG S
Sbjct: 456 S-PAPAYTPSPAPNYNPAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKS 505
>gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens]
Length = 283
Score = 411 bits (1057), Expect = e-115
Identities = 229/331 (69%), Positives = 244/331 (73%), Gaps = 49/331 (14%)
Query: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM
Sbjct: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
Query: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP 120
THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQK
Sbjct: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQK------------- 107
Query: 121 SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL 180
+P + + F+P+ + SA S+ G
Sbjct: 108 -------VVVNSPANADYQERFNPSALKDSALSTHKPIEVKG------------------ 142
Query: 181 LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLP-GGSLPIKDLAV 239
LG KA + QYN PI +YS + + + ++ G+A G GSLPIKDLAV
Sbjct: 143 LGGKA---TIIHAQYNTPISMYSQDAIMD-------AIAGQAQAQGSDFSGSLPIKDLAV 192
Query: 240 DSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSR 299
DSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSR
Sbjct: 193 DSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSR 252
Query: 300 ERFETERNSPRFAKLRNWHHGLSAQILNVKS 330
ERFETERNSPRFAKLRNWHHGLSAQILNVKS
Sbjct: 253 ERFETERNSPRFAKLRNWHHGLSAQILNVKS 283
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 348 bits (892), Expect = 5e-96
Identities = 198/300 (66%), Positives = 213/300 (71%), Gaps = 49/300 (16%)
Query: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM
Sbjct: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
Query: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP 120
THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQK
Sbjct: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQK------------- 107
Query: 121 SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL 180
+P + + F+P+ + SA S+ G
Sbjct: 108 -------VVVNSPANADYQERFNPSALKDSALSTHKPIEVKG------------------ 142
Query: 181 LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLP-GGSLPIKDLAV 239
LG KA + QYN PI +YS + + + ++ G+A G GSLPIKDLAV
Sbjct: 143 LGGKA---TIIHAQYNTPISMYSQDAIMD-------AIAGQAQAQGSDFSGSLPIKDLAV 192
Query: 240 DSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSR 299
DSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSR
Sbjct: 193 DSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSR 252
Score = 39.3 bits (90), Expect = 0.005
Identities = 30/111 (27%), Positives = 45/111 (40%), Gaps = 6/111 (5%)
Query: 85 RPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAPSPSPEARASPGTPGTPELRPTFSP 144
R + ++ P V P+P + P + + + PSP+P SP TP PT++P
Sbjct: 286 RVVTTASIRPSVYQPVPASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTP 345
Query: 145 AFSRPSAFSSLAEASDPGPPRA-----SLRAKTSPEGARDLLGPKALPGSS 190
+ P+ S A +P P A + A P D K PG S
Sbjct: 346 S-PAPAYTPSPAPNYNPAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKS 395
>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
Length = 596
Score = 162 bits (410), Expect = 4e-40
Identities = 111/330 (33%), Positives = 170/330 (51%), Gaps = 34/330 (10%)
Query: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
+YSV+L GP PWGFRLQGGKDFNMPLTIS + G KAAQ+ + GD+V++IDG+N MT
Sbjct: 3 NYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMT 62
Query: 62 HLEAQNKIKSASYNLSLTLQKSK-----RPIPISTTAP-PVQTPLPVIPHQKDPALDTNG 115
HLEAQNKIK + +L++TLQ++ P+P+ P V P+P+ TN
Sbjct: 63 HLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKGEPKEVVKPVPITSPAVSKVTSTNN 122
Query: 116 SLVAPSPSP-EARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPP---------R 165
+P P + +SP P F+PA + S+ +S + + PP
Sbjct: 123 MAYNKAPRPFGSVSSPKVTSIPSPSSAFTPAHATTSSHASPSPVAAVTPPLFAASGLHAN 182
Query: 166 ASLRAKTSPEGARDLLGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGV 225
A+L A SP G A+ QP + +ET +E+A+ + +G +
Sbjct: 183 ANLSADQSPSALS--AGKTAVNVPRQP-----TVTSVCSETSQELAEGQRRGSQGDSKQQ 235
Query: 226 GLPGGSLPIKDLAVDSASPVYQAVIKSQNKPE---DEADEWARRSSNLQSRSFRILAQMT 282
P P K + V+ + Y S + ++ ++W R+ QSRSFRILAQ+T
Sbjct: 236 NGP----PRKHI-VERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQIT 290
Query: 283 GTEFMQDPDEEALRRSRERFETERNSPRFA 312
GTE +++ + + +++ ++ SP+ A
Sbjct: 291 GTEHLKESEADNTKKAN---NSQEPSPQLA 317
>gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens]
Length = 214
Score = 119 bits (299), Expect = 3e-27
Identities = 71/164 (43%), Positives = 91/164 (55%), Gaps = 26/164 (15%)
Query: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
+YSV+L GP PWGFRLQGGKDFNMPLTIS + G KAAQ+ + GD+V++IDG+N MT
Sbjct: 3 NYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMT 62
Query: 62 HLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAPS 121
HLEAQNKIK + +L++TLQ++ +A P P+PV QK + N
Sbjct: 63 HLEAQNKIKGCTGSLNMTLQRA--------SAAPKPEPVPV---QKKTQVTNN------- 104
Query: 122 PSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPR 165
PGT P RP R + F + SD R
Sbjct: 105 --------PGTVKIPPKRPPRKHIVERYTEFYHVPTHSDASKKR 140
Score = 73.6 bits (179), Expect = 2e-13
Identities = 31/78 (39%), Positives = 55/78 (70%)
Query: 252 SQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSRERFETERNSPRF 311
S+ + ++ ++W R+ QSRSFRILAQ+TGTE +++ + + ++++E+ SP++
Sbjct: 137 SKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNTKKAKEKIPLHVFSPKY 196
Query: 312 AKLRNWHHGLSAQILNVK 329
KLR+WHH +SA+ LNV+
Sbjct: 197 TKLRDWHHEVSARALNVQ 214
>gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens]
Length = 234
Score = 117 bits (293), Expect = 1e-26
Identities = 56/98 (57%), Positives = 73/98 (74%), Gaps = 3/98 (3%)
Query: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
+YSV+L GP PWGFRLQGGKDFNMPLTIS + G KAAQ+ + GD+V++IDG+N MT
Sbjct: 3 NYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMT 62
Query: 62 HLEAQNKIKSASYNLSLTLQKSK---RPIPISTTAPPV 96
HLEAQNKIK + +L++TLQ++ +P P+ P V
Sbjct: 63 HLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTV 100
Score = 73.9 bits (180), Expect = 2e-13
Identities = 42/131 (32%), Positives = 75/131 (57%), Gaps = 6/131 (4%)
Query: 204 AETLREMAQMYQMSLRG--KASGVGLPGGSLPIKDLAVDSASPVYQAVIKSQNKPE---D 258
+ET +E+A+ + +G K +P P K + V+ + Y S + +
Sbjct: 105 SETSQELAEGQRRGSQGDSKQQNGKIPPKRPPRKHI-VERYTEFYHVPTHSDASKKRLIE 163
Query: 259 EADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSRERFETERNSPRFAKLRNWH 318
+ ++W R+ QSRSFRILAQ+TGTE +++ + + ++++E+ SP++ KLR+WH
Sbjct: 164 DTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNTKKAKEKIPLHVFSPKYTKLRDWH 223
Query: 319 HGLSAQILNVK 329
H +SA+ LNV+
Sbjct: 224 HEVSARALNVQ 234
>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
Length = 487
Score = 117 bits (293), Expect = 1e-26
Identities = 56/98 (57%), Positives = 73/98 (74%), Gaps = 3/98 (3%)
Query: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
+YSV+L GP PWGFRLQGGKDFNMPLTIS + G KAAQ+ + GD+V++IDG+N MT
Sbjct: 3 NYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMT 62
Query: 62 HLEAQNKIKSASYNLSLTLQKSK---RPIPISTTAPPV 96
HLEAQNKIK + +L++TLQ++ +P P+ P V
Sbjct: 63 HLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTV 100
Score = 43.5 bits (101), Expect = 3e-04
Identities = 20/61 (32%), Positives = 39/61 (63%), Gaps = 3/61 (4%)
Query: 252 SQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSRERFETERNSPRF 311
S+ + ++ ++W R+ QSRSFRILAQ+TGTE +++ + + +++ ++ SP+
Sbjct: 151 SKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNTKKAN---NSQEPSPQL 207
Query: 312 A 312
A
Sbjct: 208 A 208
>gi|13994151 PDZ and LIM domain 1 [Homo sapiens]
Length = 329
Score = 117 bits (293), Expect = 1e-26
Identities = 95/301 (31%), Positives = 132/301 (43%), Gaps = 74/301 (24%)
Query: 5 VTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLE 64
+ L GPGPWGFRL GGKDF PL ISR+TPGSKAA + L GD++ AIDG NT MTHLE
Sbjct: 6 IDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSNMTHLE 65
Query: 65 AQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAPSPSP 124
AQN+IK + NL+ + ++ + V +PL ++ P S P
Sbjct: 66 AQNRIKGCTDNLT---------LTVARSEHKVWSPLVTEEGKRHPYKMNLAS------EP 110
Query: 125 EARASPGTPGTPELRP-TFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDLLGP 183
+ G+ P T SPA S + R T+
Sbjct: 111 QEVLHIGSAHNRSAMPFTASPASS------------------TTARVITN---------- 142
Query: 184 KALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPI------KDL 237
QYNNP GLYS+E + + +L K + G+ S P+ L
Sbjct: 143 ----------QYNNPAGLYSSENISN----FNNALESKTAASGVEANSRPLDHAQPPSSL 188
Query: 238 AVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRR 297
+D S VY+ + + Q E QS SF +L ++ +E DP++ + R
Sbjct: 189 VIDKESEVYKMLQEKQELNEPPK----------QSTSFLVLQEILESEEKGDPNKPSGFR 238
Query: 298 S 298
S
Sbjct: 239 S 239
>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
Length = 423
Score = 115 bits (289), Expect = 4e-26
Identities = 73/184 (39%), Positives = 98/184 (53%), Gaps = 21/184 (11%)
Query: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
S+ V L GP PWGFRLQGGKDFN+PL+ISR+TPG KAAQ+ ++ GD V++IDG N ++T
Sbjct: 3 SFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLT 62
Query: 62 HLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTP-----LPVIPHQKDPALDTNGS 116
H+EAQNKI++ LSL L +++ P+ + VQTP P++P L N
Sbjct: 63 HIEAQNKIRACGERLSLGLSRAQ---PVQSKPQKVQTPDKQPLRPLVPDASKQRLMENTE 119
Query: 117 LVAPSPSPEARAS-------PGT-----PGTPELRPTFS-PAFSRPSAFSSLAEASDPGP 163
P P S GT P L+ + P P+ SS + PGP
Sbjct: 120 DWRPRPGTGQSRSFRILAHLTGTEFMQDPDEEHLKKSSQVPRTEAPAPASSTPQEPWPGP 179
Query: 164 PRAS 167
S
Sbjct: 180 TAPS 183
Score = 60.1 bits (144), Expect = 3e-09
Identities = 29/58 (50%), Positives = 39/58 (67%)
Query: 252 SQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSRERFETERNSP 309
S+ + + ++W R QSRSFRILA +TGTEFMQDPDEE L++S + TE +P
Sbjct: 110 SKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQDPDEEHLKKSSQVPRTEAPAP 167
>gi|166235176 PDZ and LIM domain protein 3 isoform a [Homo sapiens]
Length = 364
Score = 114 bits (286), Expect = 9e-26
Identities = 89/285 (31%), Positives = 135/285 (47%), Gaps = 30/285 (10%)
Query: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
M +V L GP PWGFRL GG DFN PL I+RITPGSKAA + L GD+++AIDG T++M
Sbjct: 1 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
Query: 61 THLEAQNKIKSASYNLSLTLQKSKRPI---PISTTAPPVQTPLPVIPHQKDPALDTNGSL 117
TH +AQ++IK+A++ L L + + + + +S + + +D +
Sbjct: 61 THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKHN 120
Query: 118 VAPSPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGA 177
+ P P S G P+ S S SS++ S P + AK +P
Sbjct: 121 IRPKPFVIPGRSSGCS-----TPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIP 175
Query: 178 RDLLGPKALPG-SSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKD 236
++ LPG Q+N P+ LYS + + E Q + G+ + P S+P
Sbjct: 176 LEM----ELPGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPLMSEPTASVP--- 228
Query: 237 LAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQM 281
S VY+ + ++N+P + QS SFR+L M
Sbjct: 229 ----PESDVYRMLHDNRNEP----------TQPRQSGSFRVLQGM 259
>gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens]
Length = 222
Score = 114 bits (284), Expect = 2e-25
Identities = 63/141 (44%), Positives = 88/141 (62%), Gaps = 7/141 (4%)
Query: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
S+ V L GP PWGFRLQGGKDFN+PL+ISR+TPG KAAQ+ ++ GD V++IDG N ++T
Sbjct: 3 SFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLT 62
Query: 62 HLEAQNKIKSASYNLSLTLQKSK--RPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVA 119
H+EAQNKI++ LSL L +++ + P +AP P + P++ N +
Sbjct: 63 HIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPP----RYTFAPSVSLNKTARP 118
Query: 120 PSPSPEARASPGTPGTPELRP 140
P A ++P G P LRP
Sbjct: 119 FGAPPPADSAPQQNGQP-LRP 138
Score = 95.9 bits (237), Expect = 4e-20
Identities = 48/105 (45%), Positives = 66/105 (62%), Gaps = 2/105 (1%)
Query: 228 PGGSLPIKDLAVDSASPVYQAVIKSQNKPE--DEADEWARRSSNLQSRSFRILAQMTGTE 285
P G+ P D A + ++ +K + ++W R QSRSFRILA +TGTE
Sbjct: 118 PFGAPPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTE 177
Query: 286 FMQDPDEEALRRSRERFETERNSPRFAKLRNWHHGLSAQILNVKS 330
FMQDPDEE L++SRE++ E SPR+ +LR+WHH SA +LNV+S
Sbjct: 178 FMQDPDEEHLKKSREKYVLELQSPRYTRLRDWHHQRSAHVLNVQS 222
>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
Length = 457
Score = 114 bits (284), Expect = 2e-25
Identities = 63/141 (44%), Positives = 88/141 (62%), Gaps = 7/141 (4%)
Query: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
S+ V L GP PWGFRLQGGKDFN+PL+ISR+TPG KAAQ+ ++ GD V++IDG N ++T
Sbjct: 3 SFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLT 62
Query: 62 HLEAQNKIKSASYNLSLTLQKSK--RPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVA 119
H+EAQNKI++ LSL L +++ + P +AP P + P++ N +
Sbjct: 63 HIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPP----RYTFAPSVSLNKTARP 118
Query: 120 PSPSPEARASPGTPGTPELRP 140
P A ++P G P LRP
Sbjct: 119 FGAPPPADSAPQQNGQP-LRP 138
Score = 61.2 bits (147), Expect = 1e-09
Identities = 34/84 (40%), Positives = 47/84 (55%), Gaps = 2/84 (2%)
Query: 228 PGGSLPIKDLAVDSASPVYQAVIKSQNKPE--DEADEWARRSSNLQSRSFRILAQMTGTE 285
P G+ P D A + ++ +K + ++W R QSRSFRILA +TGTE
Sbjct: 118 PFGAPPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTE 177
Query: 286 FMQDPDEEALRRSRERFETERNSP 309
FMQDPDEE L++S + TE +P
Sbjct: 178 FMQDPDEEHLKKSSQVPRTEAPAP 201
>gi|19923181 PDZ and LIM domain 4 isoform 1 [Homo sapiens]
Length = 330
Score = 108 bits (269), Expect = 9e-24
Identities = 86/259 (33%), Positives = 124/259 (47%), Gaps = 27/259 (10%)
Query: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
M +SVTL GP PWGFRL GG+DF+ PLTISR+ GSKAA + L GDL+ AI+G +T+ M
Sbjct: 1 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 60
Query: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP 120
THLEAQN+IK +L+L++ RP S + P + DP +
Sbjct: 61 THLEAQNRIKGCHDHLTLSV---SRPEGRSWPSAPDDSKAQAHRIHIDPEIQDG------ 111
Query: 121 SPSPEARASPGTPGTPELRPTFSPAFSRPSAF----SSLAEASDP--------GPPRASL 168
SP+ R S G + RP+ + +P F + +EA+ P PP ++
Sbjct: 112 SPTTSRRPSGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSAD 171
Query: 169 RAKTSPEGARDLLGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSL--RGKASGVG 226
A+ P +RD + GS R P +AE + + Y + G+
Sbjct: 172 PARGLPR-SRDC---RVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWP 227
Query: 227 LPGGSLPIKDLAVDSASPV 245
PGG +K A +P+
Sbjct: 228 GPGGPRNLKPTASKLGAPL 246
>gi|196162711 PDZ and LIM domain 4 isoform 2 [Homo sapiens]
Length = 246
Score = 107 bits (268), Expect = 1e-23
Identities = 79/214 (36%), Positives = 106/214 (49%), Gaps = 17/214 (7%)
Query: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
M +SVTL GP PWGFRL GG+DF+ PLTISR+ GSKAA + L GDL+ AI+G +T+ M
Sbjct: 1 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 60
Query: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP 120
THLEAQN+IK +L+L++ RP S + P + DP +
Sbjct: 61 THLEAQNRIKGCHDHLTLSV---SRPEGRSWPSAPDDSKAQAHRIHIDPEIQDG------ 111
Query: 121 SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL 180
SP+ R S G + RP+ + +P F G A+L A+ S
Sbjct: 112 SPTTSRRPSGTGTGPEDGRPSLGSPYGQPPRF----PVPHNGSSEATLPAQMSTLHVSP- 166
Query: 181 LGPKALPGSSQPRQYNNPIGLYSA--ETLREMAQ 212
P A P PR + + L S LRE A+
Sbjct: 167 -PPSADPARGLPRSRDCRVDLGSEVYRMLREPAE 199
>gi|166235178 PDZ and LIM domain protein 3 isoform b [Homo sapiens]
Length = 316
Score = 106 bits (265), Expect = 2e-23
Identities = 84/281 (29%), Positives = 125/281 (44%), Gaps = 70/281 (24%)
Query: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
M +V L GP PWGFRL GG DFN PL I+RITPGSKAA + L GD+++AIDG T++M
Sbjct: 1 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
Query: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP 120
TH +AQ++IK+A++ L L + + + L +P
Sbjct: 61 THADAQDRIKAAAHQLCLKIDRGET------------------------------HLWSP 90
Query: 121 SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL 180
S + +A P S P F + A + + P A
Sbjct: 91 QVSEDGKAHPFKINLE----------SEPQEFKPIGTAHN---------RRAQPFVAAAN 131
Query: 181 LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKDLAVD 240
+ K S+ YN+PIGLYS +++ +L G+ G+ +P +V
Sbjct: 132 IDDKRQVVSA---SYNSPIGLYSTSNIQD-------ALHGQLRGL-IPSSPQNEPTASVP 180
Query: 241 SASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQM 281
S VY+ + ++N+P + QS SFR+L M
Sbjct: 181 PESDVYRMLHDNRNEP----------TQPRQSGSFRVLQGM 211
>gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens]
Length = 278
Score = 89.7 bits (221), Expect = 3e-18
Identities = 71/243 (29%), Positives = 113/243 (46%), Gaps = 28/243 (11%)
Query: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
M+ +V + GP PWGFR+ GG+DF+ P+ ++++ KA + L GD++VAI+G + + M
Sbjct: 1 MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60
Query: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDT------- 113
H EAQ+KI+ + L L L +S+ P T + L V+ + ++ T
Sbjct: 61 LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNG---DSSLEVLATRFQGSVRTYTESQSS 117
Query: 114 -NGSLVAPSPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKT 172
S +P+ SP +P T A SR +F SL A PG P A + +
Sbjct: 118 LRSSYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISR--SFQSL--ACSPGLPAADRLSYS 173
Query: 173 SPEGARD------------LLGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRG 220
G+R +L P P SS+P + L E E+ +M Q + G
Sbjct: 174 GRPGSRQAGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDED-SEVFKMLQENREG 232
Query: 221 KAS 223
+A+
Sbjct: 233 RAA 235
>gi|28866957 PDZ and LIM domain 2 isoform 1 [Homo sapiens]
Length = 366
Score = 89.7 bits (221), Expect = 3e-18
Identities = 71/243 (29%), Positives = 113/243 (46%), Gaps = 28/243 (11%)
Query: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
M+ +V + GP PWGFR+ GG+DF+ P+ ++++ KA + L GD++VAI+G + + M
Sbjct: 1 MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60
Query: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDT------- 113
H EAQ+KI+ + L L L +S+ P T + L V+ + ++ T
Sbjct: 61 LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNG---DSSLEVLATRFQGSVRTYTESQSS 117
Query: 114 -NGSLVAPSPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKT 172
S +P+ SP +P T A SR +F SL A PG P A + +
Sbjct: 118 LRSSYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISR--SFQSL--ACSPGLPAADRLSYS 173
Query: 173 SPEGARD------------LLGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRG 220
G+R +L P P SS+P + L E E+ +M Q + G
Sbjct: 174 GRPGSRQAGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDED-SEVFKMLQENREG 232
Query: 221 KAS 223
+A+
Sbjct: 233 RAA 235
>gi|21361888 PDZ and LIM domain 2 isoform 2 [Homo sapiens]
Length = 352
Score = 89.7 bits (221), Expect = 3e-18
Identities = 71/243 (29%), Positives = 113/243 (46%), Gaps = 28/243 (11%)
Query: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
M+ +V + GP PWGFR+ GG+DF+ P+ ++++ KA + L GD++VAI+G + + M
Sbjct: 1 MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60
Query: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDT------- 113
H EAQ+KI+ + L L L +S+ P T + L V+ + ++ T
Sbjct: 61 LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNG---DSSLEVLATRFQGSVRTYTESQSS 117
Query: 114 -NGSLVAPSPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKT 172
S +P+ SP +P T A SR +F SL A PG P A + +
Sbjct: 118 LRSSYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISR--SFQSL--ACSPGLPAADRLSYS 173
Query: 173 SPEGARD------------LLGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRG 220
G+R +L P P SS+P + L E E+ +M Q + G
Sbjct: 174 GRPGSRQAGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDED-SEVFKMLQENREG 232
Query: 221 KAS 223
+A+
Sbjct: 233 RAA 235
>gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]
Length = 977
Score = 71.6 bits (174), Expect = 9e-13
Identities = 52/171 (30%), Positives = 83/171 (48%), Gaps = 15/171 (8%)
Query: 5 VTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLE 64
VTL+G PWGFRL GG + PL +S+I S+A ++ L + D ++AI+GV+ ++H
Sbjct: 9 VTLSGGAPWGFRLHGGAEQRKPLQVSKIRRRSQAGRAGLRERDQLLAINGVSCTNLSHAS 68
Query: 65 AQNKIKSASYNLSLTLQKSKRPIPISTTAP-PVQTPLPVIPHQKDPALDTNGSLVAPSPS 123
A + I ++ L LT+Q+ P+ + +P +Q P+ P +P AP P
Sbjct: 69 AMSLIDASGNQLVLTVQRLADEGPVQSPSPHELQVLSPLSPLSPEPP-------GAPVPQ 121
Query: 124 PEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSP 174
P PG+ + P S A+ + + A+ P R R T P
Sbjct: 122 P---LQPGSLRS----PPDSEAYYGETDSDADGPATQEKPRRPRRRGPTRP 165
Score = 33.9 bits (76), Expect = 0.21
Identities = 57/232 (24%), Positives = 82/232 (35%), Gaps = 23/232 (9%)
Query: 88 PISTTAPPVQTPLPVI-PHQKDPALDTNGSLVAPSPSPEAR-ASPGTPGTPELRPTFSPA 145
P + PP P PV P P G P+PS R A P TPG RPT +
Sbjct: 430 PEAAVLPPSPLPAPVASPRPFQPG----GGAPTPAPSIFNRSARPFTPGLQGQRPTTTSV 485
Query: 146 FSRP----SAFSSLAEASDPGPPRASLRAKTS-PEGARDLLGPKALPGSSQPRQYNNPIG 200
RP A SL S PP S + T P + + GS + + P+
Sbjct: 486 IFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVT 545
Query: 201 LYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKDLAVDSASPVY-QAVIKSQNKPEDE 259
S+ +Y + + G P P A+ S + ++ A ++ +PE
Sbjct: 546 ATSS--------LYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAP 597
Query: 260 ADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRS--RERFETERNSP 309
A +R RI T +Q+ R+ R E +NSP
Sbjct: 598 A-PGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSP 648
>gi|193083191 synaptopodin 2 isoform c [Homo sapiens]
Length = 1109
Score = 64.7 bits (156), Expect = 1e-10
Identities = 59/218 (27%), Positives = 96/218 (44%), Gaps = 30/218 (13%)
Query: 5 VTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLE 64
+++TG PWGFRLQGGK+ PL +++I SKA+ S L +GD VV+I+G +T+ E
Sbjct: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
Query: 65 AQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPH---------QKDPALDTNG 115
++S + +L + +++ I + + L + H Q PA T
Sbjct: 69 VIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQC 128
Query: 116 SLVAPSP-------SPEARASPGTPGT--PELRPTFSPAFSRPSA----------FSSLA 156
+ +P + R+ P G+ E P++ A P +
Sbjct: 129 TEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAEELILREKV 188
Query: 157 EASDPGPPRASLRAKTSPEGARDLLGP-KALPGSSQPR 193
EA PGP L+ S E + GP ALPG+ + +
Sbjct: 189 EAVQPGPV-VELQLSLSQERHKGASGPLVALPGAEKSK 225
>gi|193083185 synaptopodin 2 isoform b [Homo sapiens]
Length = 1093
Score = 64.7 bits (156), Expect = 1e-10
Identities = 59/218 (27%), Positives = 96/218 (44%), Gaps = 30/218 (13%)
Query: 5 VTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLE 64
+++TG PWGFRLQGGK+ PL +++I SKA+ S L +GD VV+I+G +T+ E
Sbjct: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
Query: 65 AQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPH---------QKDPALDTNG 115
++S + +L + +++ I + + L + H Q PA T
Sbjct: 69 VIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQC 128
Query: 116 SLVAPSP-------SPEARASPGTPGT--PELRPTFSPAFSRPSA----------FSSLA 156
+ +P + R+ P G+ E P++ A P +
Sbjct: 129 TEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAEELILREKV 188
Query: 157 EASDPGPPRASLRAKTSPEGARDLLGP-KALPGSSQPR 193
EA PGP L+ S E + GP ALPG+ + +
Sbjct: 189 EAVQPGPV-VELQLSLSQERHKGASGPLVALPGAEKSK 225
>gi|193083183 synaptopodin 2 isoform a [Homo sapiens]
Length = 1261
Score = 64.7 bits (156), Expect = 1e-10
Identities = 59/218 (27%), Positives = 96/218 (44%), Gaps = 30/218 (13%)
Query: 5 VTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLE 64
+++TG PWGFRLQGGK+ PL +++I SKA+ S L +GD VV+I+G +T+ E
Sbjct: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
Query: 65 AQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPH---------QKDPALDTNG 115
++S + +L + +++ I + + L + H Q PA T
Sbjct: 69 VIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQC 128
Query: 116 SLVAPSP-------SPEARASPGTPGT--PELRPTFSPAFSRPSA----------FSSLA 156
+ +P + R+ P G+ E P++ A P +
Sbjct: 129 TEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAEELILREKV 188
Query: 157 EASDPGPPRASLRAKTSPEGARDLLGP-KALPGSSQPR 193
EA PGP L+ S E + GP ALPG+ + +
Sbjct: 189 EAVQPGPV-VELQLSLSQERHKGASGPLVALPGAEKSK 225
>gi|74272284 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform c [Homo sapiens]
Length = 1462
Score = 62.4 bits (150), Expect = 5e-10
Identities = 49/179 (27%), Positives = 78/179 (43%), Gaps = 31/179 (17%)
Query: 3 YSVTLT-GPGPWGFRLQGGKDFNMPLTISRITPGSKAAQ-SQLSQGDLVVAIDGVNTDTM 60
Y+V L G +GF L+GG+++NM L + R+ A + ++ GD ++ I+G T M
Sbjct: 1122 YTVELERGAKGFGFSLRGGREYNMDLYVLRLAEDGPAERCGKMRIGDEILEINGETTKNM 1181
Query: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP 120
H A IK+ + L L++ +P + DP+ D +G P
Sbjct: 1182 KHSRAIELIKNGGRRVRLFLKRGDGSVP-----------------EYDPSSDRHGPATGP 1224
Query: 121 SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARD 179
PE RA P P L ++ P L ++S G RA R P+G+R+
Sbjct: 1225 QGVPEVRAGPDRRQHPSLESSYPP---------DLHKSSPHGEKRAHAR---DPKGSRE 1271
Score = 37.0 bits (84), Expect = 0.024
Identities = 33/135 (24%), Positives = 58/135 (42%), Gaps = 4/135 (2%)
Query: 13 WGFRLQGGKDFNMPLTI-SRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLEAQNKIKS 71
+GF + GG + + L I S + G A ++ GD++V+++ TH + +S
Sbjct: 482 FGFTVVGGDEPDEFLQIKSLVLDGPAALDGKMETGDVIVSVNDTCVLGHTHAQVVKIFQS 541
Query: 72 ASYNLSLTLQKSK-RPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAPSPSPEARASP 130
S+ L+ + P+P P V K+P + NG SP+ + +
Sbjct: 542 IPIGASVDLELCRGYPLPFDPDDPNTSLVTSVAILDKEPII-VNGQETYDSPASHSSKTG 600
Query: 131 GTPGTPELRPTFSPA 145
G + RP+ SPA
Sbjct: 601 KVNGMKDARPS-SPA 614
Score = 35.0 bits (79), Expect = 0.092
Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 5/120 (4%)
Query: 43 LSQGDLVVAIDGVNTDTMTHLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPV 102
L +GDL+V ++ N +TH + + + +TL + +P+ +P Q PL
Sbjct: 680 LKEGDLIVEVNKKNVQALTHNQVVDMLVECPKGSEVTLLVQRGGLPVPKKSPKSQ-PLER 738
Query: 103 IPHQKDP--ALDTNGSLVAPSPSPEARASPGTPGTPELRP--TFSPAFSRPSAFSSLAEA 158
Q ++ ++ SL SPS + P P P T S +P F A++
Sbjct: 739 KDSQNSSQHSVSSHRSLHTASPSHSTQVLPEFPPAEAQAPDQTDSSGQKKPDPFKIWAQS 798
Score = 33.5 bits (75), Expect = 0.27
Identities = 24/98 (24%), Positives = 40/98 (40%), Gaps = 10/98 (10%)
Query: 13 WGFRLQGGKDFNMPLTISRITP-GSKAAQSQLSQGDLVVAIDGVNTDTMTHLEA----QN 67
+GFR+ GG + P+ I I P G+ +L GD ++ +DG +H Q
Sbjct: 823 FGFRILGGNEPGEPIYIGHIVPLGAADTDGRLRSGDELICVDGTPVIGKSHQLVVQLMQQ 882
Query: 68 KIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPH 105
K NL++ +R + + + P P H
Sbjct: 883 AAKQGHVNLTV-----RRKVVFAVPKTENEVPSPASSH 915
>gi|27436957 membrane associated guanylate kinase, WW and PDZ domain
containing 2 [Homo sapiens]
Length = 1455
Score = 54.3 bits (129), Expect = 1e-07
Identities = 35/131 (26%), Positives = 60/131 (45%), Gaps = 8/131 (6%)
Query: 9 GPGPWGFRLQGGKDFNMPLTISRITPGSKAAQS-QLSQGDLVVAIDGVNTDTMTHLEAQN 67
G +GF ++GG+++ M L + R+ A ++ ++ GD ++ I+G +T MTH A
Sbjct: 1153 GAKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIE 1212
Query: 68 KIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAPSPS---- 123
IKS + L L++ +P P +P P + + + L SPS
Sbjct: 1213 LIKSGGRRVRLLLKRGTGQVPEYDEPAPWSSPAAAAPGLPEVGVSLDDGLAPFSPSHPAP 1272
Query: 124 ---PEARASPG 131
P + SPG
Sbjct: 1273 PSDPSHQISPG 1283
Score = 44.7 bits (104), Expect = 1e-04
Identities = 35/126 (27%), Positives = 59/126 (46%), Gaps = 13/126 (10%)
Query: 16 RLQGGKDFNMPLTISRITPGSKAAQ-SQLSQGDLVVAIDGVNTDTMTHLEAQNKIKSASY 74
R + G +P I RI GS A + ++L GD ++A++G + M H + IK A
Sbjct: 941 RPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGL 1000
Query: 75 NLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAPSPSPEARASPGTPG 134
+++L + + + T+AP + P+ Q+ P SP A+ SP TP
Sbjct: 1001 SVTLRIIPQEE-LNSPTSAPSSEKQSPMA--QQSPLAQQ---------SPLAQPSPATPN 1048
Query: 135 TPELRP 140
+P +P
Sbjct: 1049 SPIAQP 1054
Score = 39.7 bits (91), Expect = 0.004
Identities = 36/126 (28%), Positives = 55/126 (43%), Gaps = 9/126 (7%)
Query: 13 WGFRLQGGKDFNMPLTISR-ITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLEAQNKIKS 71
+GFR+ GG + P+ I I GS +L GD +V +DG+ TH + +
Sbjct: 788 FGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHH 847
Query: 72 ASYNLSLTLQKSKRPIPISTTAPP-VQTPLPVIPHQKDPALD----TNGSLVAPSPS--- 123
A+ N + L ++ + P ++P V H P D TN + APS +
Sbjct: 848 AARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASP 907
Query: 124 PEARAS 129
PE AS
Sbjct: 908 PEGFAS 913
Score = 34.3 bits (77), Expect = 0.16
Identities = 26/105 (24%), Positives = 46/105 (43%), Gaps = 2/105 (1%)
Query: 13 WGFRLQGGKDFNMPLTISRITPGSKAAQS-QLSQGDLVVAIDGVNTDTMTHLEAQNKIKS 71
+GF + GG + + L + + P AAQ ++ GD++V I+ V TH + +S
Sbjct: 436 FGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQS 495
Query: 72 ASYNLSLTLQKSK-RPIPISTTAPPVQTPLPVIPHQKDPALDTNG 115
S+ L + P+P P P+ ++ P + NG
Sbjct: 496 VPIGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNG 540
Score = 32.7 bits (73), Expect = 0.46
Identities = 33/122 (27%), Positives = 49/122 (40%), Gaps = 21/122 (17%)
Query: 43 LSQGDLVVAIDGVNTDTMTHLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPV 102
L +GDL+V I+ N ++H E + +K +L I P +TP P+
Sbjct: 640 LCEGDLIVEINQQNVQNLSHTEVVDILKDCPIGSETSL-----IIHRGGFFSPWKTPKPI 694
Query: 103 IPHQKDPALDTNGSLVAPSPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPG 162
+ ++ SP+ S P P+ P F PA R S+F EA DP
Sbjct: 695 MDRWENQG------------SPQTSLS--APAIPQNLP-FPPALHR-SSFPDSTEAFDPR 738
Query: 163 PP 164
P
Sbjct: 739 KP 740
Score = 31.2 bits (69), Expect = 1.3
Identities = 16/64 (25%), Positives = 27/64 (42%)
Query: 101 PVIPHQKDPALDTNGSLVAPSPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASD 160
P ++ P ++ NG +V P S S G G +P +P +S+P + +
Sbjct: 232 PEEEEEERPVVNGNGVVVTPESSEHEDKSAGASGEMPSQPYPAPVYSQPEELKEQMDDTK 291
Query: 161 PGPP 164
P P
Sbjct: 292 PTKP 295
>gi|118600967 shroom family member 4 [Homo sapiens]
Length = 1493
Score = 49.7 bits (117), Expect = 4e-06
Identities = 33/84 (39%), Positives = 46/84 (54%), Gaps = 2/84 (2%)
Query: 5 VTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQ-LSQGDLVVAIDGVNTDTMTHL 63
V L G PWGF L+GG + PLT+S+I G KAA SQ + GD +V I+G +
Sbjct: 13 VQLQGGAPWGFTLKGGLEHCEPLTVSKIEDGGKAALSQKMRTGDELVNINGTPL-YGSRQ 71
Query: 64 EAQNKIKSASYNLSLTLQKSKRPI 87
EA IK + L L +++ P+
Sbjct: 72 EALILIKGSFRILKLIVRRRNAPV 95
>gi|11321640 basic beta 1 syntrophin [Homo sapiens]
Length = 538
Score = 49.7 bits (117), Expect = 4e-06
Identities = 32/100 (32%), Positives = 50/100 (50%), Gaps = 6/100 (6%)
Query: 11 GPWGFRLQGGKDFNMPLTISRITPGSKAAQSQ-LSQGDLVVAIDGVNTDTMTHLEAQNKI 69
G G ++GGK+ MP+ IS+I G A Q+Q L GD +++++G + TH EA +
Sbjct: 121 GGLGISIKGGKENKMPILISKIFKGLAADQTQALYVGDAILSVNGADLRDATHDEAVQAL 180
Query: 70 KSASYNLSLTLQKSKRPIPISTTAPPV-----QTPLPVIP 104
K A + L ++ + P PV +TP P P
Sbjct: 181 KRAGKEVLLEVKYMREATPYVKKGSPVSEIGWETPPPESP 220
>gi|4502175 apical protein of Xenopus-like [Homo sapiens]
Length = 1616
Score = 49.7 bits (117), Expect = 4e-06
Identities = 29/79 (36%), Positives = 44/79 (55%), Gaps = 2/79 (2%)
Query: 5 VTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQ-SQLSQGDLVVAIDGVNTDTMTHL 63
V L+G PWGF L+GG++ PL I++I GSKAA +L GD +V I+ +
Sbjct: 29 VQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQ- 87
Query: 64 EAQNKIKSASYNLSLTLQK 82
EA +K + L L +++
Sbjct: 88 EAICLVKGSHKTLKLVVKR 106
>gi|13376349 PDZ domain containing 7 [Homo sapiens]
Length = 517
Score = 48.5 bits (114), Expect = 8e-06
Identities = 22/72 (30%), Positives = 46/72 (63%), Gaps = 1/72 (1%)
Query: 14 GFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLEAQNKIKSAS 73
GF ++GGK+F + + +S++ G A ++ + GD V+A +GV D ++H +A +K +
Sbjct: 223 GFNIRGGKEFGLGIYVSKVDHGGLAEENGIKVGDQVLAANGVRFDDISHSQAVEVLKGQT 282
Query: 74 YNLSLTLQKSKR 85
+ + LT++++ R
Sbjct: 283 H-IMLTIKETGR 293
Score = 38.5 bits (88), Expect = 0.008
Identities = 20/84 (23%), Positives = 47/84 (55%), Gaps = 1/84 (1%)
Query: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
S V + G GF ++GG + + + +S++ GS A ++ L GD + ++G++ ++ T
Sbjct: 86 SVRVEKSPAGRLGFSVRGGSEHGLGIFVSKVEEGSSAERAGLCVGDKITEVNGLSLESTT 145
Query: 62 HLEAQNKIKSASYNLSLTLQKSKR 85
+ + K+ ++S L + +++ R
Sbjct: 146 -MGSAVKVLTSSSRLHMMVRRMGR 168
>gi|155969695 membrane-associated guanylate kinase-related 3 isoform
2 [Homo sapiens]
Length = 1125
Score = 48.5 bits (114), Expect = 8e-06
Identities = 30/87 (34%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Query: 9 GPGPWGFRLQGGKDFNMPLTISRIT-PGSKAAQSQLSQGDLVVAIDGVNTDTMTHLEAQN 67
GP +GF L+GGK++NM L I R+ G ++ GD +V I+G T +TH A
Sbjct: 1027 GPRGFGFSLRGGKEYNMGLFILRLAEDGPAIKDGRIHVGDQIVEINGEPTQGITHTRAIE 1086
Query: 68 KIKSASYNLSLTLQKSKRPIPISTTAP 94
I++ + L L+ IP AP
Sbjct: 1087 LIQAGGNKVLLLLRPGTGLIPDHGLAP 1113
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,683,417
Number of Sequences: 37866
Number of extensions: 836895
Number of successful extensions: 6723
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 197
Number of HSP's successfully gapped in prelim test: 696
Number of HSP's that attempted gapping in prelim test: 4658
Number of HSP's gapped (non-prelim): 2309
length of query: 330
length of database: 18,247,518
effective HSP length: 103
effective length of query: 227
effective length of database: 14,347,320
effective search space: 3256841640
effective search space used: 3256841640
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.