Guide to the Human Genome
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Search of human proteins with 239756028

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239756028 PREDICTED: hypothetical protein [Homo sapiens]
         (255 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239756028 PREDICTED: hypothetical protein [Homo sapiens]           542   e-155
gi|169206162 PREDICTED: hypothetical protein [Homo sapiens]           142   4e-34
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      66   3e-11
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      65   4e-11
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    64   1e-10
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    64   1e-10
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    60   1e-09
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    60   1e-09
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    60   1e-09
gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s...    59   4e-09
gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s...    59   4e-09
gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo ...    59   4e-09
gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens]     59   4e-09
gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo s...    57   1e-08
gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo s...    57   1e-08
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     56   3e-08
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       56   3e-08
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]    56   3e-08
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    56   3e-08
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    56   3e-08
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    56   3e-08
gi|154759255 collagen, type XXVIII precursor [Homo sapiens]            56   3e-08
gi|119508426 alpha 3 type IX collagen [Homo sapiens]                   55   5e-08
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          55   6e-08
gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]       55   6e-08
gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [H...    55   6e-08
gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Ho...    55   6e-08
gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Hom...    55   6e-08
gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]        55   6e-08
gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]        55   6e-08

>gi|239756028 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 255

 Score =  542 bits (1397), Expect = e-155
 Identities = 255/255 (100%), Positives = 255/255 (100%)

Query: 1   MDKVLNVNFTVEERGASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWG 60
           MDKVLNVNFTVEERGASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWG
Sbjct: 1   MDKVLNVNFTVEERGASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWG 60

Query: 61  GRGAGSQSLPRGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWL 120
           GRGAGSQSLPRGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWL
Sbjct: 61  GRGAGSQSLPRGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWL 120

Query: 121 SVPASRGVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGVGSESPP 180
           SVPASRGVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGVGSESPP
Sbjct: 121 SVPASRGVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGVGSESPP 180

Query: 181 RWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPR 240
           RWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPR
Sbjct: 181 RWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPR 240

Query: 241 CDGDPKSRGGRGAGS 255
           CDGDPKSRGGRGAGS
Sbjct: 241 CDGDPKSRGGRGAGS 255


>gi|169206162 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 120

 Score =  142 bits (357), Expect = 4e-34
 Identities = 84/157 (53%), Positives = 92/157 (58%), Gaps = 39/157 (24%)

Query: 48  MGVLKARGGRAWGGRGAGSQSLPR--GGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQ 105
           MGVL+ARG         G    PR  GGAS  CDGGP+S+G KRG L  P L  G ASP 
Sbjct: 1   MGVLRARGE-------VGLALSPRLVGGASPPCDGGPESRGRKRGCLLSPCLV-GVASPS 52

Query: 106 CDGGPKSQGGKSGWLSVPASRGVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGV 165
           CD GPKSQ GK GWLSVPAS                             LGVPPPPA+GV
Sbjct: 53  CDDGPKSQRGKRGWLSVPAS-----------------------------LGVPPPPAIGV 83

Query: 166 QRARGGRGVGSESPPRWGCLPTCDGGPKSQGGKRGWL 202
            R+RGGRG GS+SPPR GCLP CDGGP+S+  KRG L
Sbjct: 84  LRSRGGRGAGSQSPPRGGCLPPCDGGPESRERKRGCL 120



 Score =  100 bits (248), Expect = 2e-21
 Identities = 59/116 (50%), Positives = 67/116 (57%), Gaps = 4/116 (3%)

Query: 134 MGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGVGSESPPRWGCL-PTCDGGP 192
           MG+LRARG  G       P  +G   PP  G   +RG +     SP   G   P+CD GP
Sbjct: 1   MGVLRARGEVGLALS---PRLVGGASPPCDGGPESRGRKRGCLLSPCLVGVASPSCDDGP 57

Query: 193 KSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKSR 248
           KSQ GKRGWLSVPAS  V P PA+GVLR+RGGRG        GG  P CDG P+SR
Sbjct: 58  KSQRGKRGWLSVPASLGVPPPPAIGVLRSRGGRGAGSQSPPRGGCLPPCDGGPESR 113



 Score = 92.0 bits (227), Expect = 4e-19
 Identities = 48/77 (62%), Positives = 54/77 (70%), Gaps = 5/77 (6%)

Query: 16  ASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGAS 75
           ASP    GPKSQ GK GW S+ AS  VPPPPA+GVL++R     GGRGAGSQS PRGG  
Sbjct: 49  ASPSCDDGPKSQRGKRGWLSVPASLGVPPPPAIGVLRSR-----GGRGAGSQSPPRGGCL 103

Query: 76  ARCDGGPKSQGGKRGWL 92
             CDGGP+S+  KRG L
Sbjct: 104 PPCDGGPESRERKRGCL 120



 Score = 65.1 bits (157), Expect = 6e-11
 Identities = 43/94 (45%), Positives = 49/94 (52%), Gaps = 1/94 (1%)

Query: 163 MGVQRARGGRGVGSESPPRWGCLPTCDGGPKSQGGKRGWLSVPAS-WVVSPTPAMGVLRA 221
           MGV RARG  G+        G  P CDGGP+S+G KRG L  P    V SP+   G    
Sbjct: 1   MGVLRARGEVGLALSPRLVGGASPPCDGGPESRGRKRGCLLSPCLVGVASPSCDDGPKSQ 60

Query: 222 RGGRGVALSPYLMGGASPRCDGDPKSRGGRGAGS 255
           RG RG    P  +G   P   G  +SRGGRGAGS
Sbjct: 61  RGKRGWLSVPASLGVPPPPAIGVLRSRGGRGAGS 94


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 80/262 (30%), Positives = 95/262 (36%), Gaps = 49/262 (18%)

Query: 18  PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLP--RGGAS 75
           PPG  GP+ Q G  G+         P P        + G   G  G G Q  P   G   
Sbjct: 565 PPGPSGPRGQPGVMGF---------PGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETG 615

Query: 76  ARCDGGPKSQGGKRGWLSVPS------LPRGGASPQCDGGPKSQG--GKSGWLSVPASRG 127
            +   GP   GG +G    P       LP  G  P  +G P   G  G +G    P  +G
Sbjct: 616 PQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKG 675

Query: 128 VA-------PPGAMGILRARGGRGTGSQSPLPASLGVPPPPAM----GVQRARGGR-GVG 175
            A       PPG  G    RGG G         + G P PP      G+Q   G R G+G
Sbjct: 676 DAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLG 735

Query: 176 SESPPRWGCLPTCDGGPKSQG-----GKRGWLSVPASWVVSPTPAMGVLRARGGRGVALS 230
           S  P      P   GGP + G     G RG    P   +  P PA       G +G   +
Sbjct: 736 SPGPKGDKGEP---GGPGADGVPGKDGPRG----PTGPIGPPGPA----GQPGDKGEGGA 784

Query: 231 PYLMGGASPRCDGDPKSRGGRG 252
           P L G A PR  G P  RG  G
Sbjct: 785 PGLPGIAGPR--GSPGERGETG 804



 Score = 63.2 bits (152), Expect = 2e-10
 Identities = 70/244 (28%), Positives = 89/244 (36%), Gaps = 30/244 (12%)

Query: 19  PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGR-GAGSQSLPRGGASAR 77
           PG  GP+   G  G          PP PA       G +  GG  G    + PRG    R
Sbjct: 755 PGKDGPRGPTGPIG----------PPGPA----GQPGDKGEGGAPGLPGIAGPRGSPGER 800

Query: 78  CDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVA-PPGAMGI 136
            + GP    G  G       P GG   +   G K +GG  G    P   G A PPG  G+
Sbjct: 801 GETGPPGPAGFPGAPGQNGEP-GGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGV 859

Query: 137 LRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGG--RGVGSESPPRWGCLPTCDG---- 190
              RG  G    +  P + G+P PP         G     G + PP         G    
Sbjct: 860 KGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGV 919

Query: 191 -GPKSQGGKRGWLSVPASWVVSPTPA-MGVLRARGGRGVALSPYLMGGASPRCDGDPKSR 248
            GPK   G+ G    P +      P  +G+    G RG+A  P + G   PR  G P  +
Sbjct: 920 SGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPG---PR--GSPGPQ 974

Query: 249 GGRG 252
           G +G
Sbjct: 975 GVKG 978



 Score = 62.0 bits (149), Expect = 5e-10
 Identities = 81/270 (30%), Positives = 95/270 (35%), Gaps = 37/270 (13%)

Query: 13  ERG-ASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGG-RGAGSQSLP 70
           ERG A  PG+ G K + GK G  S         P A G   A G R   G  G   +  P
Sbjct: 448 ERGEAGIPGVPGAKGEDGKDG--SPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGP 505

Query: 71  RGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQG--------GKSGWLSV 122
            G   A    GP+   G+ G   VP  P     P   GGP S G        G+SG    
Sbjct: 506 AGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGP 565

Query: 123 PASRGV-APPGAMGILRARGGRGTGSQSPLPASLGVP----PPPAMGVQRARGGRG---- 173
           P   G    PG MG    +G  G   ++      G P    PP   G    +G  G    
Sbjct: 566 PGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGP 625

Query: 174 ------VGSESPPRWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPA----MGVLRARG 223
                  G   P     LP   GGP  + GK G             P      G    RG
Sbjct: 626 GGDKGDTGPPGPQGLQGLPG-TGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERG 684

Query: 224 GRGVALSPYLMGGASPRCDGDPKSRGGRGA 253
             G+A +P L GGA P     P   GG+GA
Sbjct: 685 PPGLAGAPGLRGGAGP-----PGPEGGKGA 709



 Score = 62.0 bits (149), Expect = 5e-10
 Identities = 81/281 (28%), Positives = 99/281 (35%), Gaps = 62/281 (22%)

Query: 13   ERGA-------SPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGA- 64
            ERGA        PPG+ GP    G +G           PP   GV   RG    GG GA 
Sbjct: 826  ERGAPGEKGEGGPPGVAGPPGGSGPAG-----------PPGPQGVKGERGSP--GGPGAA 872

Query: 65   ---GSQSLPRGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDG--GPKSQGGKSGW 119
               G++ LP G   +  + GP    G  G    P       +P   G  GPK   G+ G 
Sbjct: 873  GFPGARGLP-GPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGE 931

Query: 120  LSVPASRGV-APPGAMGILRARGGRGTGSQSPLPASLGVP----------PPPAMGVQRA 168
               P ++G    PG +GI    G RG      +P   G P           P A G+   
Sbjct: 932  KGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGE 991

Query: 169  RGGRG-------------VGSESPPRWGCLPTCDGGPKSQG--GKRGWLSVP-ASWVVSP 212
            RG  G              G +  P    LP  DG P  +G  G+ G    P A     P
Sbjct: 992  RGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGP 1051

Query: 213  TPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKSRGGRGA 253
               +G     G RG +      G A P   G P   G RGA
Sbjct: 1052 PGPVGPAGKSGDRGES------GPAGPA--GAPGPAGSRGA 1084



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 81/271 (29%), Positives = 100/271 (36%), Gaps = 54/271 (19%)

Query: 13  ERGA-SPPGIGGP---------KSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRA--WG 60
           ERG   PPGI GP         K   G  G          P       L    G     G
Sbjct: 241 ERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMG 300

Query: 61  GRGA----GSQSLPRGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDG-----GPK 111
            RGA    G   LP G A AR + G +   G+ G    P       SP   G     G  
Sbjct: 301 PRGAPGERGRPGLP-GAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSP 359

Query: 112 SQGGKSGWLSVPASRGVA----PPGAMGILRARGGRGTGSQSPLPASLGV-----PPPPA 162
              G  G    P  +G A    PPG  GI  + GG+G    + +P + G+     PP PA
Sbjct: 360 GSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPA 419

Query: 163 MGVQRARGGRGVGSESPPRWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRAR 222
            G   A G RG G+  P + G     + GP+   G+RG   +P           GV  A+
Sbjct: 420 -GANGAPGLRG-GAGEPGKNGA--KGEPGPR---GERGEAGIP-----------GVPGAK 461

Query: 223 GGRGVALSPYLMGGASPRCDGDPKSRGGRGA 253
           G  G   SP       P  +G P + G RGA
Sbjct: 462 GEDGKDGSP-----GEPGANGLPGAAGERGA 487



 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 53/171 (30%), Positives = 64/171 (37%), Gaps = 20/171 (11%)

Query: 19   PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRA-WGGRGAGSQSLPRGGASAR 77
            PG  GP    GKSG      S    P  A G   +RG     G RG   ++  RG A  +
Sbjct: 1049 PGPPGPVGPAGKSG--DRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIK 1106

Query: 78   CD-------GGPKSQG--GKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGV 128
                     G P S G  G++G +  P    G A P+   GP    GK G    P    +
Sbjct: 1107 GHRGFPGNPGAPGSPGPAGQQGAIGSP----GPAGPRGPVGPSGPPGKDGTSGHPGP--I 1160

Query: 129  APPGAMGILRARGGRGTGSQSPLPASLGVP--PPPAMGVQRARGGRGVGSE 177
             PPG  G    RG  G+      P   G P  P P  G   A    G+G E
Sbjct: 1161 GPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGE 1211



 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 50/182 (27%), Positives = 62/182 (34%), Gaps = 19/182 (10%)

Query: 19   PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGG-RGAGSQSLPRGGASAR 77
            PG  G + + G  G  +  A     PP  +G     G R   G  G      P G   A 
Sbjct: 1028 PGGKGDRGENGSPG--APGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAP 1085

Query: 78   CDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQG--GKSGWLSVPASRGVAPPGAMG 135
               GP+   G+ G      +      P   G P S G  G+ G +  P      P G  G
Sbjct: 1086 GPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSP-----GPAGPRG 1140

Query: 136  ILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGV-GSESPPRWGCLPTCDGGPKS 194
             +   G  G    S  P  +G P P        RG RG  GSE  P     P   G P +
Sbjct: 1141 PVGPSGPPGKDGTSGHPGPIGPPGP--------RGNRGERGSEGSPGHPGQPGPPGPPGA 1192

Query: 195  QG 196
             G
Sbjct: 1193 PG 1194



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 47/181 (25%), Positives = 62/181 (34%), Gaps = 31/181 (17%)

Query: 86  GGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVA-------PPGAMGILR 138
           GG  G+   P+ P G   P    G     G  G+   P   G A       PPGA+G   
Sbjct: 167 GGLAGYPG-PAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSG 225

Query: 139 ARGGRGTGSQSPLPASLGVPPPPAM-------GVQRARGGRGVGSESPPRWGCLPTCDGG 191
             G  G   +   P   G+P PP +       G    +G RG    +  +         G
Sbjct: 226 PAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEK---------G 276

Query: 192 PKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKSRGGR 251
                G +G   +P         A G +  RG  G    P L G A  R  G+  +RG  
Sbjct: 277 ETGAPGLKGENGLPGE-----NGAPGPMGPRGAPGERGRPGLPGAAGAR--GNDGARGSD 329

Query: 252 G 252
           G
Sbjct: 330 G 330



 Score = 32.0 bits (71), Expect = 0.54
 Identities = 50/195 (25%), Positives = 61/195 (31%), Gaps = 42/195 (21%)

Query: 71  RGGASARCDGGPKSQGGKRGWLSVPSLPRGGASP-------QCDGGPKSQGGKSGWLSVP 123
           +G    + D GP    G+ G   +P  P    SP        C  GP++   +  + S  
Sbjct: 102 QGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQ--YDSYD 159

Query: 124 ASRGVAP------PGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGVGSE 177
              GVA       PG  G     G  GT      P S G   PP    Q        G  
Sbjct: 160 VKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQ-------AGPS 212

Query: 178 SPPRWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGA 237
            PP     P    GP    GK G    P                 G RG+   P + G A
Sbjct: 213 GPPG----PPGAIGPSGPAGKDGESGRPG--------------RPGERGLPGPPGIKGPA 254

Query: 238 SPRCDGDPKSRGGRG 252
                G P  +G RG
Sbjct: 255 G--IPGFPGMKGHRG 267


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 79/257 (30%), Positives = 90/257 (35%), Gaps = 47/257 (18%)

Query: 16  ASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGR-GAGSQSLPRGGA 74
           A PPG  GP    G  G  ++ A     P    G    +G R   G  G    + P G  
Sbjct: 331 AGPPGPTGPAGPPGFPG--AVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNP 388

Query: 75  SARCDGGPKSQGGKRGWLSVPSLP--RGGASPQCDGGPKSQGGKSGWLSVPASRG----- 127
            A    G K   G  G    P  P  RG + PQ  GGP    G SG    P S+G     
Sbjct: 389 GADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAK 448

Query: 128 --------VAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGVGSESP 179
                     PPG  G    RG RG       P   G+P PP  G +   G RG      
Sbjct: 449 GEPGPVGVQGPPGPAGEEGKRGARGE------PGPTGLPGPP--GERGGPGSRG------ 494

Query: 180 PRWGCLPTCDG--GPKSQGGKRGWLSVPASWVVSPTPA--MGVLRARGGRGVALSPYLMG 235
                 P  DG  GPK   G+RG    PA    SP  A   G     G +G+  SP    
Sbjct: 495 -----FPGADGVAGPKGPAGERG-SPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSP---- 544

Query: 236 GASPRCDGDPKSRGGRG 252
             SP  DG     G  G
Sbjct: 545 -GSPGPDGKTGPPGPAG 560



 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 82/270 (30%), Positives = 94/270 (34%), Gaps = 43/270 (15%)

Query: 13  ERGAS-PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGG-RGAGSQSLP 70
           ERG   PPG  GP+   G  G  +  A      P A G   A G +   G RGA     P
Sbjct: 684 ERGVQGPPGPAGPRGANGAPG--NDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGP 741

Query: 71  RGGASARCDGGPKSQGGKRGWLSVPSL--------PRGGASPQCDGGPKSQGGKSGWLSV 122
           +G    R D GPK   G  G   V  L        P G    + + GP    G +G    
Sbjct: 742 KGD---RGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGA 798

Query: 123 PASRG----------VAPPGAMGILRARGGRGTGSQS-----PLPASLGVPPPPA--MGV 165
           P  RG            PPGA G   A+G  G          P PA    PP P   +G 
Sbjct: 799 PGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGA 858

Query: 166 QRARGGRGVGSESPPRWGCLPTCDG--GPKSQGGKRGWLSVPASWVVSPTPAMGVLRARG 223
             A+G R  GS  PP     P   G  GP    G  G    P      P    G    RG
Sbjct: 859 PGAKGAR--GSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPP-----GPAGKEGGKGPRG 911

Query: 224 GRGVALSPYLMGGASPRCDGDPKSRGGRGA 253
             G A  P  +G   P   G    +G  GA
Sbjct: 912 ETGPAGRPGEVGPPGP--PGPAGEKGSPGA 939



 Score = 58.5 bits (140), Expect = 5e-09
 Identities = 74/250 (29%), Positives = 89/250 (35%), Gaps = 24/250 (9%)

Query: 16   ASPPGIGGP------KSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSL 69
            A PPG  GP      K   G++G          P PP     K   G A G  GA     
Sbjct: 892  AGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPG-ADGPAGAPGTPG 950

Query: 70   PRGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVA 129
            P+G A  R   G   Q G+RG+  +P  P G    Q   G   + G  G +  P   G  
Sbjct: 951  PQGIAGQRGVVGLPGQRGERGFPGLPG-PSGEPGKQGPSGASGERGPPGPMGPPGLAG-- 1007

Query: 130  PPGAMGILRARGGRGTGSQSPLPASLG-------VPPPPAMGVQRARGGRGVGSESPPRW 182
            PPG  G   A G  G+  +   P + G         PP A G   A G  G   +S  R 
Sbjct: 1008 PPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRG 1067

Query: 183  GCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCD 242
               P    GP    G RG    PA     P    G    +G RG+       G   P   
Sbjct: 1068 ETGPAGPAGPVGPVGARG----PAG-PQGPRGDKGETGEQGDRGIKGHRGFSGLQGP--P 1120

Query: 243  GDPKSRGGRG 252
            G P S G +G
Sbjct: 1121 GPPGSPGEQG 1130



 Score = 57.8 bits (138), Expect = 9e-09
 Identities = 77/267 (28%), Positives = 93/267 (34%), Gaps = 48/267 (17%)

Query: 20  GIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGG-RGAGSQSLPRGGASARC 78
           G  GP  + GK G         +P PP       RGG    G  GA   + P+G A  R 
Sbjct: 458 GPPGPAGEEGKRGARGEPGPTGLPGPPG-----ERGGPGSRGFPGADGVAGPKGPAGERG 512

Query: 79  DGGPKSQGGKRGWLSVPS---------LPRGGASPQCDG-----GPKSQGGKSGWLSVPA 124
             GP    G  G    P          L     SP  DG     GP  Q G+ G    P 
Sbjct: 513 SPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPG 572

Query: 125 SRGVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPA----------MGVQRARGGRGV 174
           +RG A     G++   G +G   +       GVP PP            G Q   G  G 
Sbjct: 573 ARGQA-----GVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGP 627

Query: 175 GSE-------SPPRWGCLPTCDGGPKSQGGKRGWLSVPAS-WVVSPTPAMGVLRARGGRG 226
             E         P +  LP    GP  + GK G   VP       P+ A G     G RG
Sbjct: 628 AGERGEQGPAGSPGFQGLPG-PAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERG 686

Query: 227 VALSPYLMGGASPR-CDGDPKSRGGRG 252
           V   P   G A PR  +G P + G +G
Sbjct: 687 VQGPP---GPAGPRGANGAPGNDGAKG 710



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 82/287 (28%), Positives = 100/287 (34%), Gaps = 55/287 (19%)

Query: 13  ERGAS-PPGIGGPKSQWGKSGWFSIAASWRVPPPP-------------------AMGVLK 52
           E GA  PPG  GP  + G+ G         +P P                    A G   
Sbjct: 615 EAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSG 674

Query: 53  ARGGRAWGGRGAGSQSLPRGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKS 112
           ARG R + G   G Q  P G A  R   G     G +G    P  P    +P   G P  
Sbjct: 675 ARGERGFPGE-RGVQG-PPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMP-- 730

Query: 113 QGGKSGWLSVPASRG----VAPPGAMGILRARGGRG-TGSQSPLPASLGVP--------- 158
             G+ G   +P  +G      P GA G     G RG TG   P P   G P         
Sbjct: 731 --GERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGP-PGPAGAPGDKGESGPS 787

Query: 159 -PPPAMGVQRARGGRG-VGSESPPRWGCLPTCDGGPKSQG-----GKRGWLSVPA----S 207
            P    G + A G RG  G   P  +   P  DG P ++G     G +G    P     +
Sbjct: 788 GPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPA 847

Query: 208 WVVSPTPAMGVLRARGGRGVALSPYLMG--GASPRCDGDPKSRGGRG 252
               P   +G   A+G RG A  P   G  GA+ R  G P   G  G
Sbjct: 848 GPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRV-GPPGPSGNAG 893



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 66/244 (27%), Positives = 81/244 (33%), Gaps = 27/244 (11%)

Query: 18  PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASAR 77
           P G  GP  + G+ G          P PP         G+  G  G      P+G     
Sbjct: 198 PQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKP-GRPGERGPPGPQGARGLP 256

Query: 78  CDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGV-------AP 130
              G     G RG+  +    +G A P    GPK + G  G    P   G          
Sbjct: 257 GTAGLPGMKGHRGFSGLDGA-KGDAGP---AGPKGEPGSPGENGAPGQMGPRGLPGERGR 312

Query: 131 PGAMGILRARGGRG-TGSQSPLPASLGVPPPPAMGVQRARGGRGVGSESPPRWGCLP--- 186
           PGA G   ARG  G TG+  P P   G   PP  G   A G +G      PR    P   
Sbjct: 313 PGAPGPAGARGNDGATGAAGP-PGPTGPAGPP--GFPGAVGAKGEAGPQGPRGSEGPQGV 369

Query: 187 TCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPK 246
             + GP    G  G    P +         G   A G  G+A +P   G   P     P+
Sbjct: 370 RGEPGPPGPAGAAGPAGNPGA-----DGQPGAKGANGAPGIAGAPGFPGARGP---SGPQ 421

Query: 247 SRGG 250
             GG
Sbjct: 422 GPGG 425



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 84/266 (31%), Positives = 99/266 (37%), Gaps = 58/266 (21%)

Query: 13  ERGA-SPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPR 71
           ERG   PPG  GP  + G++G        + PP PA G    RG +   G   G Q LP 
Sbjct: 597 ERGVPGPPGAVGPAGKDGEAGA-------QGPPGPA-GPAGERGEQGPAG-SPGFQGLPG 647

Query: 72  GGASARCDGGPKSQG-----------GKRGWLSVPSL-----PRGGASPQ-CDGGPKSQG 114
                   G P  QG           G RG    P       P G A P+  +G P + G
Sbjct: 648 PAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDG 707

Query: 115 --GKSGWLSVPASRGVAPPGAMGILRARGGRGTGSQSPLPASLG----VPPPPAMGVQRA 168
             G +G    P S+G   PG  G+   RG  G      LP   G      P  A G    
Sbjct: 708 AKGDAGAPGAPGSQGA--PGLQGMPGERGAAG------LPGPKGDRGDAGPKGADGSPGK 759

Query: 169 RGGRGV-GSESPPRWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGV 227
            G RG+ G   PP     P    G K + G  G    PA     PT A G   A G RG 
Sbjct: 760 DGVRGLTGPIGPPG----PAGAPGDKGESGPSG----PA----GPTGARG---APGDRGE 804

Query: 228 ALSPYLMGGAS-PRCDGDPKSRGGRG 252
              P   G A  P  DG P ++G  G
Sbjct: 805 PGPPGPAGFAGPPGADGQPGAKGEPG 830



 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 72/267 (26%), Positives = 89/267 (33%), Gaps = 35/267 (13%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVP-------PPPAMGVLKARGGRAW-GGRGAGSQSL 69
            P G  G K + G SG      +   P       PP   G     G     G +G    + 
Sbjct: 774  PAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAG 833

Query: 70   PRGGASARCDGGPKSQGGKRGWLSVPSLP--RGGASPQCDGGPKSQGGKSGWLSVPASRG 127
             +G A      GP    G  G +  P     RG A P    G     G +G +  P   G
Sbjct: 834  AKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPP---GATGFPGAAGRVGPPGPSG 890

Query: 128  VA----PPGAMGILRARGGRGTGSQSPLPASLGVPPPPA----MGVQRARGGRGVGSESP 179
             A    PPG  G    +G RG    +  P  +G P PP      G   A G  G      
Sbjct: 891  NAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPG 950

Query: 180  PRWGCLPTCDGGPKSQGGKRGWLSVPA-SWVVSPTPAMGVLRARGGRGVALSPYLMG--- 235
            P+         G   Q G+RG+  +P  S         G    RG  G    P L G   
Sbjct: 951  PQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPG 1010

Query: 236  -----GA-----SPRCDGDPKSRGGRG 252
                 GA     SP  DG P ++G RG
Sbjct: 1011 ESGREGAPGAEGSPGRDGSPGAKGDRG 1037



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 55/193 (28%), Positives = 67/193 (34%), Gaps = 17/193 (8%)

Query: 70  PRGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGK-----SGWLSVPA 124
           P+G    R   GP    G+ G    P LP G   P    GP   GG      S      +
Sbjct: 113 PKGDTGPRGPRGPAGPPGRDGIPGQPGLP-GPPGPPGPPGPPGLGGNFAPQLSYGYDEKS 171

Query: 125 SRGVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPA-MGVQRARGGRGV-GSESPPRW 182
           + G++ PG MG     G RG       P   G   PP   G   A G  G  G   PP  
Sbjct: 172 TGGISVPGPMG---PSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPG- 227

Query: 183 GCLPTCDGGPKSQGGKRGWLSVPASWVVSPTP-AMGVLRARGGRGVALSPYLMGGASPR- 240
                 D G   + G+ G    P        P   G+   +G RG +      G A P  
Sbjct: 228 ---KNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAG 284

Query: 241 CDGDPKSRGGRGA 253
             G+P S G  GA
Sbjct: 285 PKGEPGSPGENGA 297



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 43/151 (28%), Positives = 53/151 (35%), Gaps = 20/151 (13%)

Query: 19   PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASARC 78
            PG  GP    GKSG      +    P   +G +        G RG      PRG      
Sbjct: 1051 PGAPGPVGPAGKSG--DRGETGPAGPAGPVGPV--------GARGPAGPQGPRGDKGETG 1100

Query: 79   DGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAP-------- 130
            + G +   G RG+  +   P    SP  + GP    G +G    P S G AP        
Sbjct: 1101 EQGDRGIKGHRGFSGLQGPPGPPGSPG-EQGPSGASGPAGPRGPPGSAG-APGKDGLNGL 1158

Query: 131  PGAMGILRARGGRGTGSQSPLPASLGVPPPP 161
            PG +G    RG  G       P   G P PP
Sbjct: 1159 PGPIGPPGPRGRTGDAGPVGPPGPPGPPGPP 1189


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 73/248 (29%), Positives = 94/248 (37%), Gaps = 39/248 (15%)

Query: 12  EERGASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPR 71
           E   A PPG  GP  + G+ G    +    +P PP        G    GG+  G Q +P 
Sbjct: 637 ETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP--------GPPGEGGK-PGDQGVP- 686

Query: 72  GGASARCDGGPKSQGGKRGWLSVPSL-----PRGGASPQCDGGPKSQGGKSGWLSVPASR 126
           G A A    GP+ + G  G    P       PRG        GPK   G +G    P ++
Sbjct: 687 GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAG---PPGAQ 743

Query: 127 GVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGV-GSESPPRWGCL 185
           G  PPG  G+   RG  G          +G   P   G     GGRG+ G   PP     
Sbjct: 744 G--PPGLQGMPGERGAAGIAGPKGDRGDVGEKGPE--GAPGKDGGRGLTGPIGPP----- 794

Query: 186 PTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGAS-PRCDGD 244
                GP    G++G +  P      P  + G   A G RG    P   G A  P  DG 
Sbjct: 795 -----GPAGANGEKGEVGPP-----GPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQ 844

Query: 245 PKSRGGRG 252
           P ++G +G
Sbjct: 845 PGAKGEQG 852



 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 80/275 (29%), Positives = 98/275 (35%), Gaps = 54/275 (19%)

Query: 16  ASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGR-AWGGRGAGSQSLPRGGA 74
           A P G  GP  + GK G            P  +G +   G R A G RG   Q    G  
Sbjct: 476 AGPQGAPGPAGEEGKRGARG--------EPGGVGPIGPPGERGAPGNRGFPGQDGLAGPK 527

Query: 75  SARCDGGPKSQGGKRGWLSVPSLP--------------RGGASPQCDGGPKSQGGKSGWL 120
            A  + GP    G +G    P  P               G A PQ   GP    G+ G  
Sbjct: 528 GAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRP 587

Query: 121 SVPASRGV-APPGAMGI---LRARGGRGTGSQSPLPASLGV--------------PPPPA 162
             P  +G    PG MG      A G  G   +  LP + G+              PP PA
Sbjct: 588 GPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPA 647

Query: 163 MGVQRARGGRGVGSESPPRWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRAR 222
            G    RG +  G+  P  +  LP    GP  +GGK G   VP         A G++  R
Sbjct: 648 -GPAGERGEQ--GAPGPSGFQGLPG-PPGPPGEGGKPGDQGVPGE-----AGAPGLVGPR 698

Query: 223 GGRGV---ALSPYLMGGASPR-CDGDPKSRGGRGA 253
           G RG      SP   G   PR   G P + G +GA
Sbjct: 699 GERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGA 733



 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 69/237 (29%), Positives = 83/237 (35%), Gaps = 49/237 (20%)

Query: 19  PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASARC 78
           PG  GPK   G +G           PP A G    +G    G RGA   + P+G      
Sbjct: 725 PGTDGPKGASGPAG-----------PPGAQGPPGLQGMP--GERGAAGIAGPKGDRGDVG 771

Query: 79  DGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAPPGAMGILR 138
           + GP+   GK G        RG   P    GP    G+ G         V PPG  G   
Sbjct: 772 EKGPEGAPGKDGG-------RGLTGPIGPPGPAGANGEKG--------EVGPPGPAGSAG 816

Query: 139 ARGGRGTGSQSPLPASLG-VPPPPAMGVQRARGGRGVGSESPPRWGCLPTCDGGPKSQGG 197
           ARG  G   ++  P   G   PP A G   A+G +G   +            G P  QG 
Sbjct: 817 ARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDA--------GAPGPQG- 867

Query: 198 KRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMG--GASPRCDGDPKSRGGRG 252
                    S    P    GV   +G RG    P   G  GA+ R  G P S G  G
Sbjct: 868 --------PSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRV-GPPGSNGNPG 915



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 83/280 (29%), Positives = 101/280 (36%), Gaps = 64/280 (22%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASAR 77
            PPG  G   + G+ G          PP PA G   ARG  A G RG      P G A   
Sbjct: 793  PPGPAGANGEKGEVG----------PPGPA-GSAGARG--APGERGETGPPGPAGFAGPP 839

Query: 78   -CDGGPKSQG-----GKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAPP 131
              DG P ++G     G++G    P  P+G   P    GP+   G +G      ++G  PP
Sbjct: 840  GADGQPGAKGEQGEAGQKGDAGAPG-PQG---PSGAPGPQGPTGVTGPKGARGAQG--PP 893

Query: 132  GAMGILRARGGRGTGSQSPLPASLGVPPPPAM-GVQRARGGRG----------VGSESPP 180
            GA G   A G  G    +  P   G P P    G + ARG  G           G   PP
Sbjct: 894  GATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPP 953

Query: 181  RWGCLPTCDG--------GPKSQGGKRGWLSVPA-----SWVVSPTP--------AMGVL 219
                 P  DG        GP+   G+RG + +P       +   P P        A G  
Sbjct: 954  GEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGAS 1013

Query: 220  RARGGRGVALSPYLMGGA-------SPRCDGDPKSRGGRG 252
              RG  G    P L G A       SP  DG P   G  G
Sbjct: 1014 GDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAG 1053



 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 75/273 (27%), Positives = 91/273 (33%), Gaps = 51/273 (18%)

Query: 13  ERGASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRG 72
           ERG  P G+ GPK   G  G          P  P +   +   GR  G  G   +  P G
Sbjct: 532 ERG--PSGLAGPKGANGDPGR---------PGEPGLPGARGLTGRP-GDAGPQGKVGPSG 579

Query: 73  GASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGV---- 128
                   GP    G RG   V   P     P+   G   + G+ G    P  RG+    
Sbjct: 580 APGEDGRPGPPGPQGARGQPGVMGFP----GPKGANGEPGKAGEKGLPGAPGLRGLPGKD 635

Query: 129 ------APPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGVGSES---- 178
                  PPG  G    RG +G    S      G P PP  G +   G +GV  E+    
Sbjct: 636 GETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGK--PGDQGVPGEAGAPG 693

Query: 179 ---PPRWGCLPTCDGGPKSQG--GKRGWLSVP-------ASWVVSPTPAMGVLRARGGRG 226
              P      P   G P +QG  G RG    P       AS    P  A G    +G  G
Sbjct: 694 LVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPG 753

Query: 227 VALSPYLMGGASPRCD-------GDPKSRGGRG 252
              +  + G    R D       G P   GGRG
Sbjct: 754 ERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRG 786



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 50/174 (28%), Positives = 63/174 (36%), Gaps = 24/174 (13%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASAR 77
            PPG  GP    GK G    A         A G +   G    G RG      PRG     
Sbjct: 1072 PPGSPGPAGPTGKQGDRGEAG--------AQGPMGPSGPA--GARGIQGPQGPRGDKGEA 1121

Query: 78   CDGGPKSQGGKRGWLSVPSLP--------RGGASPQCDGGPKSQGGKSGWLSVPASRGVA 129
             + G +   G RG+  +  LP        +G + P    GP+   G  G      + G+ 
Sbjct: 1122 GEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGI- 1180

Query: 130  PPGAMGILRARGGRG-TGSQSP--LPASLGVPPPPAMGV-QRARGGRGVGSESP 179
             PG +G    RG  G TG   P   P   G P PP  G+   A  G G   + P
Sbjct: 1181 -PGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGP 1233



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 73/261 (27%), Positives = 86/261 (32%), Gaps = 41/261 (15%)

Query: 19  PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASARC 78
           PG  GP    G +G          P  P     K   G   G RG      PRG      
Sbjct: 350 PGPAGPPGPVGPAGG---------PGFPGAPGAKGEAGPT-GARGPEGAQGPRGEPGTPG 399

Query: 79  DGGPKSQGGKRGWLSVPSLPRGGASPQCDG-----GPKSQGGKSGWLSVPASRG-VAPPG 132
             GP    G  G   +P       +P   G     GP+   G  G       +G    PG
Sbjct: 400 SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG 459

Query: 133 AMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGR----GVGSESPPRWGCLPTC 188
             G    +G +G     P PA     P PA G +  RG R    GVG   PP     P  
Sbjct: 460 IAGFKGEQGPKG----EPGPAGPQGAPGPA-GEEGKRGARGEPGGVGPIGPPGERGAPGN 514

Query: 189 DG--------GPKSQGGKRGWLSVPASWVVSPTPAM----GVLRARG--GRGVALSPYLM 234
            G        GPK   G+RG   +      +  P      G+  ARG  GR     P   
Sbjct: 515 RGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGK 574

Query: 235 GGAS--PRCDGDPKSRGGRGA 253
            G S  P  DG P   G +GA
Sbjct: 575 VGPSGAPGEDGRPGPPGPQGA 595



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 70/261 (26%), Positives = 89/261 (34%), Gaps = 51/261 (19%)

Query: 16  ASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGAS 75
           A+  G  GPK Q G+ G        + PP P               +G   +  PRG   
Sbjct: 94  ATASGQPGPKGQKGEPGDIKDIVGPKGPPGP---------------QGPAGEQGPRGD-- 136

Query: 76  ARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDG--GPKSQGG------------KSGWLS 121
            R D G K   G RG    P  P     P   G  GP   GG            K+G   
Sbjct: 137 -RGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQ 195

Query: 122 VPASRGVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGVGSESPPR 181
           +   +G  P G MG     G  G         + G P  P  GV    G RG     PP 
Sbjct: 196 LGVMQG--PMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEP--GVSGPMGPRG-----PPG 246

Query: 182 WGCLPTCDG--GPKSQGGKRGWLSVPASWVVSPTPAMGVLRAR-------GGRGVALSPY 232
               P  DG  G   + G+RG      +     TP +  ++         G +G A +P 
Sbjct: 247 PPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPG 306

Query: 233 LMG-GASPRCDGDPKSRGGRG 252
           + G   SP  +G P   G RG
Sbjct: 307 VKGESGSPGENGSPGPMGPRG 327



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 48/173 (27%), Positives = 66/173 (38%), Gaps = 23/173 (13%)

Query: 19   PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGR-GAGSQSLPRGGASAR 77
            PG  GP    G  G   +A    +     +G+   RG R + G  G   +   +G   A 
Sbjct: 959  PGDDGPSGAEGPPGPQGLAGQRGI-----VGLPGQRGERGFPGLPGPSGEPGKQGAPGAS 1013

Query: 78   CDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQG--------GKSGWLSVPASRGVA 129
             D GP    G  G       P    SP  DG P   G        G++G +  P +    
Sbjct: 1014 GDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA--PG 1071

Query: 130  PPGAMGILRARGGRG----TGSQSPLPASLGVPPPPAMGVQRARGGRGVGSES 178
            PPG+ G     G +G     G+Q P+  S    P  A G+Q  +G RG   E+
Sbjct: 1072 PPGSPGPAGPTGKQGDRGEAGAQGPMGPS---GPAGARGIQGPQGPRGDKGEA 1121



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 54/203 (26%), Positives = 65/203 (32%), Gaps = 36/203 (17%)

Query: 70  PRGGASARCDGGPKSQGGKRGWLS---VPSLPRGGASPQCDGGPKSQGGKSGWLSVPASR 126
           P   A+A    GPK Q G+ G +     P  P G   P  + GP+   G  G    P  R
Sbjct: 90  PTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPR 149

Query: 127 GVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAM----------GVQRARGGRGVGS 176
           G             G  GT      P   G P PP +          G     GG  +G 
Sbjct: 150 G-----------RDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV 198

Query: 177 ESPPRWGCLPTCDGGPKSQGGKRGWLSVP-------ASWVVSPTPAMGVLRARGGRGVAL 229
              P     P    GP    G +G+   P        S  + P    G     G  G A 
Sbjct: 199 MQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG 258

Query: 230 SPYLMGGASPRCDGDPKSRGGRG 252
            P   G A  R  G P  +G RG
Sbjct: 259 KP---GKAGER--GPPGPQGARG 276


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 73/248 (29%), Positives = 94/248 (37%), Gaps = 39/248 (15%)

Query: 12  EERGASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPR 71
           E   A PPG  GP  + G+ G    +    +P PP        G    GG+  G Q +P 
Sbjct: 568 ETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP--------GPPGEGGK-PGDQGVP- 617

Query: 72  GGASARCDGGPKSQGGKRGWLSVPSL-----PRGGASPQCDGGPKSQGGKSGWLSVPASR 126
           G A A    GP+ + G  G    P       PRG        GPK   G +G    P ++
Sbjct: 618 GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAG---PPGAQ 674

Query: 127 GVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGV-GSESPPRWGCL 185
           G  PPG  G+   RG  G          +G   P   G     GGRG+ G   PP     
Sbjct: 675 G--PPGLQGMPGERGAAGIAGPKGDRGDVGEKGPE--GAPGKDGGRGLTGPIGPP----- 725

Query: 186 PTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGAS-PRCDGD 244
                GP    G++G +  P      P  + G   A G RG    P   G A  P  DG 
Sbjct: 726 -----GPAGANGEKGEVGPP-----GPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQ 775

Query: 245 PKSRGGRG 252
           P ++G +G
Sbjct: 776 PGAKGEQG 783



 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 80/275 (29%), Positives = 98/275 (35%), Gaps = 54/275 (19%)

Query: 16  ASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGR-AWGGRGAGSQSLPRGGA 74
           A P G  GP  + GK G            P  +G +   G R A G RG   Q    G  
Sbjct: 407 AGPQGAPGPAGEEGKRGARG--------EPGGVGPIGPPGERGAPGNRGFPGQDGLAGPK 458

Query: 75  SARCDGGPKSQGGKRGWLSVPSLP--------------RGGASPQCDGGPKSQGGKSGWL 120
            A  + GP    G +G    P  P               G A PQ   GP    G+ G  
Sbjct: 459 GAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRP 518

Query: 121 SVPASRGV-APPGAMGI---LRARGGRGTGSQSPLPASLGV--------------PPPPA 162
             P  +G    PG MG      A G  G   +  LP + G+              PP PA
Sbjct: 519 GPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPA 578

Query: 163 MGVQRARGGRGVGSESPPRWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRAR 222
            G    RG +  G+  P  +  LP    GP  +GGK G   VP         A G++  R
Sbjct: 579 -GPAGERGEQ--GAPGPSGFQGLPG-PPGPPGEGGKPGDQGVPGE-----AGAPGLVGPR 629

Query: 223 GGRGV---ALSPYLMGGASPR-CDGDPKSRGGRGA 253
           G RG      SP   G   PR   G P + G +GA
Sbjct: 630 GERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGA 664



 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 69/237 (29%), Positives = 83/237 (35%), Gaps = 49/237 (20%)

Query: 19  PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASARC 78
           PG  GPK   G +G           PP A G    +G    G RGA   + P+G      
Sbjct: 656 PGTDGPKGASGPAG-----------PPGAQGPPGLQGMP--GERGAAGIAGPKGDRGDVG 702

Query: 79  DGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAPPGAMGILR 138
           + GP+   GK G        RG   P    GP    G+ G         V PPG  G   
Sbjct: 703 EKGPEGAPGKDGG-------RGLTGPIGPPGPAGANGEKG--------EVGPPGPAGSAG 747

Query: 139 ARGGRGTGSQSPLPASLG-VPPPPAMGVQRARGGRGVGSESPPRWGCLPTCDGGPKSQGG 197
           ARG  G   ++  P   G   PP A G   A+G +G   +            G P  QG 
Sbjct: 748 ARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDA--------GAPGPQG- 798

Query: 198 KRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMG--GASPRCDGDPKSRGGRG 252
                    S    P    GV   +G RG    P   G  GA+ R  G P S G  G
Sbjct: 799 --------PSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRV-GPPGSNGNPG 846



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 83/280 (29%), Positives = 101/280 (36%), Gaps = 64/280 (22%)

Query: 18  PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASAR 77
           PPG  G   + G+ G          PP PA G   ARG  A G RG      P G A   
Sbjct: 724 PPGPAGANGEKGEVG----------PPGPA-GSAGARG--APGERGETGPPGPAGFAGPP 770

Query: 78  -CDGGPKSQG-----GKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAPP 131
             DG P ++G     G++G    P  P+G   P    GP+   G +G      ++G  PP
Sbjct: 771 GADGQPGAKGEQGEAGQKGDAGAPG-PQG---PSGAPGPQGPTGVTGPKGARGAQG--PP 824

Query: 132 GAMGILRARGGRGTGSQSPLPASLGVPPPPAM-GVQRARGGRG----------VGSESPP 180
           GA G   A G  G    +  P   G P P    G + ARG  G           G   PP
Sbjct: 825 GATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPP 884

Query: 181 RWGCLPTCDG--------GPKSQGGKRGWLSVPA-----SWVVSPTP--------AMGVL 219
                P  DG        GP+   G+RG + +P       +   P P        A G  
Sbjct: 885 GEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGAS 944

Query: 220 RARGGRGVALSPYLMGGA-------SPRCDGDPKSRGGRG 252
             RG  G    P L G A       SP  DG P   G  G
Sbjct: 945 GDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAG 984



 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 75/273 (27%), Positives = 91/273 (33%), Gaps = 51/273 (18%)

Query: 13  ERGASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRG 72
           ERG  P G+ GPK   G  G          P  P +   +   GR  G  G   +  P G
Sbjct: 463 ERG--PSGLAGPKGANGDPGR---------PGEPGLPGARGLTGRP-GDAGPQGKVGPSG 510

Query: 73  GASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGV---- 128
                   GP    G RG   V   P     P+   G   + G+ G    P  RG+    
Sbjct: 511 APGEDGRPGPPGPQGARGQPGVMGFP----GPKGANGEPGKAGEKGLPGAPGLRGLPGKD 566

Query: 129 ------APPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGVGSES---- 178
                  PPG  G    RG +G    S      G P PP  G +   G +GV  E+    
Sbjct: 567 GETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGK--PGDQGVPGEAGAPG 624

Query: 179 ---PPRWGCLPTCDGGPKSQG--GKRGWLSVP-------ASWVVSPTPAMGVLRARGGRG 226
              P      P   G P +QG  G RG    P       AS    P  A G    +G  G
Sbjct: 625 LVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPG 684

Query: 227 VALSPYLMGGASPRCD-------GDPKSRGGRG 252
              +  + G    R D       G P   GGRG
Sbjct: 685 ERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRG 717



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 50/174 (28%), Positives = 63/174 (36%), Gaps = 24/174 (13%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASAR 77
            PPG  GP    GK G    A         A G +   G    G RG      PRG     
Sbjct: 1003 PPGSPGPAGPTGKQGDRGEAG--------AQGPMGPSGPA--GARGIQGPQGPRGDKGEA 1052

Query: 78   CDGGPKSQGGKRGWLSVPSLP--------RGGASPQCDGGPKSQGGKSGWLSVPASRGVA 129
             + G +   G RG+  +  LP        +G + P    GP+   G  G      + G+ 
Sbjct: 1053 GEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGI- 1111

Query: 130  PPGAMGILRARGGRG-TGSQSP--LPASLGVPPPPAMGV-QRARGGRGVGSESP 179
             PG +G    RG  G TG   P   P   G P PP  G+   A  G G   + P
Sbjct: 1112 -PGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGP 1164



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 73/261 (27%), Positives = 86/261 (32%), Gaps = 41/261 (15%)

Query: 19  PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASARC 78
           PG  GP    G +G          P  P     K   G   G RG      PRG      
Sbjct: 281 PGPAGPPGPVGPAGG---------PGFPGAPGAKGEAGPT-GARGPEGAQGPRGEPGTPG 330

Query: 79  DGGPKSQGGKRGWLSVPSLPRGGASPQCDG-----GPKSQGGKSGWLSVPASRG-VAPPG 132
             GP    G  G   +P       +P   G     GP+   G  G       +G    PG
Sbjct: 331 SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG 390

Query: 133 AMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGR----GVGSESPPRWGCLPTC 188
             G    +G +G     P PA     P PA G +  RG R    GVG   PP     P  
Sbjct: 391 IAGFKGEQGPKG----EPGPAGPQGAPGPA-GEEGKRGARGEPGGVGPIGPPGERGAPGN 445

Query: 189 DG--------GPKSQGGKRGWLSVPASWVVSPTPAM----GVLRARG--GRGVALSPYLM 234
            G        GPK   G+RG   +      +  P      G+  ARG  GR     P   
Sbjct: 446 RGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGK 505

Query: 235 GGAS--PRCDGDPKSRGGRGA 253
            G S  P  DG P   G +GA
Sbjct: 506 VGPSGAPGEDGRPGPPGPQGA 526



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 48/173 (27%), Positives = 66/173 (38%), Gaps = 23/173 (13%)

Query: 19   PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGR-GAGSQSLPRGGASAR 77
            PG  GP    G  G   +A    +     +G+   RG R + G  G   +   +G   A 
Sbjct: 890  PGDDGPSGAEGPPGPQGLAGQRGI-----VGLPGQRGERGFPGLPGPSGEPGKQGAPGAS 944

Query: 78   CDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQG--------GKSGWLSVPASRGVA 129
             D GP    G  G       P    SP  DG P   G        G++G +  P +    
Sbjct: 945  GDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA--PG 1002

Query: 130  PPGAMGILRARGGRG----TGSQSPLPASLGVPPPPAMGVQRARGGRGVGSES 178
            PPG+ G     G +G     G+Q P+  S    P  A G+Q  +G RG   E+
Sbjct: 1003 PPGSPGPAGPTGKQGDRGEAGAQGPMGPS---GPAGARGIQGPQGPRGDKGEA 1052



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 68/254 (26%), Positives = 86/254 (33%), Gaps = 51/254 (20%)

Query: 23  GPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASARCDGGP 82
           GPK Q G+ G        + PP P               +G   +  PRG    R D G 
Sbjct: 32  GPKGQKGEPGDIKDIVGPKGPPGP---------------QGPAGEQGPRGD---RGDKGE 73

Query: 83  KSQGGKRGWLSVPSLPRGGASPQCDG--GPKSQGG------------KSGWLSVPASRGV 128
           K   G RG    P  P     P   G  GP   GG            K+G   +   +G 
Sbjct: 74  KGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQG- 132

Query: 129 APPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGVGSESPPRWGCLPTC 188
            P G MG     G  G         + G P  P  GV    G RG     PP     P  
Sbjct: 133 -PMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEP--GVSGPMGPRG-----PPGPPGKPGD 184

Query: 189 DG--GPKSQGGKRGWLSVPASWVVSPTPAMGVLRAR-------GGRGVALSPYLMG-GAS 238
           DG  G   + G+RG      +     TP +  ++         G +G A +P + G   S
Sbjct: 185 DGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS 244

Query: 239 PRCDGDPKSRGGRG 252
           P  +G P   G RG
Sbjct: 245 PGENGSPGPMGPRG 258



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 55/205 (26%), Positives = 65/205 (31%), Gaps = 42/205 (20%)

Query: 74  ASARCDG------GPKSQGGKRGWLSV---PSLPRGGASPQCDGGPKSQGGKSGWLSVPA 124
           A  RC G      GPK Q G+ G +     P  P G   P  + GP+   G  G    P 
Sbjct: 19  AVLRCQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPG 78

Query: 125 SRGVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAM----------GVQRARGGRGV 174
            RG             G  GT      P   G P PP +          G     GG  +
Sbjct: 79  PRG-----------RDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQL 127

Query: 175 GSESPPRWGCLPTCDGGPKSQGGKRGWLSVP-------ASWVVSPTPAMGVLRARGGRGV 227
           G    P     P    GP    G +G+   P        S  + P    G     G  G 
Sbjct: 128 GVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGE 187

Query: 228 ALSPYLMGGASPRCDGDPKSRGGRG 252
           A  P   G A  R  G P  +G RG
Sbjct: 188 AGKP---GKAGER--GPPGPQGARG 207


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 80/262 (30%), Positives = 101/262 (38%), Gaps = 44/262 (16%)

Query: 20   GIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAW----GGRGAGSQSLPRGGAS 75
            G+ G K + G+ G+           P   G +  +G R      G RG      P+G A 
Sbjct: 784  GLKGSKGEKGEDGF-----------PGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAG 832

Query: 76   ARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSV---PASRGVA--- 129
               D GP  Q G++G L VP LP G    Q   GPK   G  G+        +RGVA   
Sbjct: 833  PTGDPGPSGQAGEKGKLGVPGLP-GYPGRQ---GPKGSTGFPGFPGANGEKGARGVAGKP 888

Query: 130  -PPGAMGILRARGGRG----TGSQSPLPASLGVPPPPAMGVQRARGGRG-VGSESPPRWG 183
             P G  G    RG RG    TG   P   S G  PP   G +  +G +G VG   P    
Sbjct: 889  GPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPP 948

Query: 184  CLPTCDG-----GPKSQGGKRGWLSVPASWVV----SPTPAMGVLRARGGRGVALSPYLM 234
              P  DG     G + + G +G    P    V     PT   G +  RG  G    P   
Sbjct: 949  GPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQ 1008

Query: 235  G--GASPR--CDGDPKSRGGRG 252
            G  GA+ +    GDP  +G  G
Sbjct: 1009 GLPGAAGKEGAKGDPGPQGISG 1030



 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 81/300 (27%), Positives = 102/300 (34%), Gaps = 76/300 (25%)

Query: 19  PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASARC 78
           PG+ G K   G+ G          P PP    ++   G   G RG   ++ PRG    R 
Sbjct: 618 PGLPGDKGHRGERG------PQGPPGPPGDDGMRGEDGEI-GPRGLPGEAGPRGLLGPRG 670

Query: 79  DGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRG-VAPPGAM--- 134
             G   Q G  G +  P  P+G   PQ + GP  Q G  G   +P  +G + PPG     
Sbjct: 671 TPGAPGQPGMAG-VDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQ 729

Query: 135 ---------GILRARGGRGTGSQSPLPASLGVPPPPA-------MGVQRARGGRGV---- 174
                    G     G  G   QS    +LG P P          GV+ A G RG+    
Sbjct: 730 GKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSK 789

Query: 175 ------------------------------GSESP--PRWGCLPTCDGGPKSQGGKRGWL 202
                                         G + P  P+    PT D GP  Q G++G L
Sbjct: 790 GEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKL 849

Query: 203 SVPA--SWVVSPTPA--------MGVLRARGGRGVALSPYLMGGASPRCDGDPKSRGGRG 252
            VP    +     P          G    +G RGVA  P   G   P   G   SRG RG
Sbjct: 850 GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP--TGPRGSRGARG 907



 Score = 58.5 bits (140), Expect = 5e-09
 Identities = 73/259 (28%), Positives = 94/259 (36%), Gaps = 49/259 (18%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASAR 77
            PPG  GP+   G +G     A     PP ++G +   G +  G  G      P G A   
Sbjct: 1232 PPGPPGPRGPQGPNG-----ADGPQGPPGSVGSVGGVGEK--GEPGEAGNPGPPGEAGV- 1283

Query: 78   CDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQG--GKSGWLSVPASRGVAPPGAMG 135
              GGPK + G++G    P        P   G P   G  G  G +  P   G  PPG  G
Sbjct: 1284 --GGPKGERGEKGEAGPPG---AAGPPGAKGPPGDDGPKGNPGPVGFPGDPG--PPGEPG 1336

Query: 136  ILRARGGRGTGSQSPLPASLGVP----------------PPPAMGVQRARGGRG----VG 175
                 G  G   +   P   G P                PP A G +  +G +G     G
Sbjct: 1337 PAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAG 1396

Query: 176  SESPP-RWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLM 234
            +E PP + G  P    GP  + G  G   +P      P    G+  A G  G    P  M
Sbjct: 1397 AEGPPGKTG--PVGPQGPAGKPGPEGLRGIP-----GPVGEQGLPGAAGQDG---PPGPM 1446

Query: 235  GGAS-PRCDGDPKSRGGRG 252
            G    P   GDP S+G +G
Sbjct: 1447 GPPGLPGLKGDPGSKGEKG 1465



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 64/239 (26%), Positives = 89/239 (37%), Gaps = 17/239 (7%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAW--GGRGAGSQSLPRGGAS 75
            PPG  G K   G+ G    A    V  P  +       G     G +G   +   +G   
Sbjct: 1094 PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG 1153

Query: 76   ARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGV-APPGAM 134
             + + GP    G +G +  P +  G   P    GP+ Q G  G      +RG   PPG +
Sbjct: 1154 DKGENGPPGPPGLQGPVGAPGIAGGDGEP----GPRGQQGMFGQKGDEGARGFPGPPGPI 1209

Query: 135  GILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGV-GSESPPRWGCLPTCDG-GP 192
            G+    G  G   ++     +G P PP  G +  +G  G  G + PP  G + +  G G 
Sbjct: 1210 GLQGLPGPPGEKGENGDVGPMGPPGPP--GPRGPQGPNGADGPQGPP--GSVGSVGGVGE 1265

Query: 193  KSQGGKRGWLSVPA-SWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKSRGG 250
            K + G+ G    P  + V  P    G     G  G A  P   G   P  D  PK   G
Sbjct: 1266 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP---GAKGPPGDDGPKGNPG 1321



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 62/245 (25%), Positives = 82/245 (33%), Gaps = 42/245 (17%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLP--RGGAS 75
            P G+ GP+   G++G          P PP                  G Q LP   G   
Sbjct: 977  PGGVVGPQGPTGETGPIGERGHPGPPGPP------------------GEQGLPGAAGKEG 1018

Query: 76   ARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAPPGAMG 135
            A+ D GP+   GK G   +   P     P   G P  +GG+             PPG +G
Sbjct: 1019 AKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQ---------GPPGPVG 1069

Query: 136  ILRARGGRGTGSQSPLPASLGVPPPP-------AMGVQRARGGRGVGSESPPRWGCLPTC 188
                RG  GT     LP   G   PP       A G +  +G  G      P     P  
Sbjct: 1070 SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG 1129

Query: 189  DGGPKSQGGKRGWLSVPA-SWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKS 247
              G   + G +G +  P            G     G +G   +P + GG     DG+P  
Sbjct: 1130 PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG-----DGEPGP 1184

Query: 248  RGGRG 252
            RG +G
Sbjct: 1185 RGQQG 1189



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 58/224 (25%), Positives = 73/224 (32%), Gaps = 29/224 (12%)

Query: 44  PPPAMGVL----KARGGRAWGGRGAGSQSLPRGGASARCDGGPKSQGGKRGWLSVPSLPR 99
           PP  MG+        G  + G +G      P+G    +   GP  + GKRG         
Sbjct: 542 PPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD---- 597

Query: 100 GGASPQCDGGPKSQGGKSGWLSVPASRG-------VAPPGAMGILRARGGRGTGSQSPLP 152
           GG     + G K   G  G   +P  +G         PPG  G    RG  G      LP
Sbjct: 598 GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLP 657

Query: 153 ASLG----VPPPPAMGVQRARGGRGVGSESPPRWGCLPTCDGGPKSQGGKRGWLSVPASW 208
              G    + P    G     G  GV     P+    P  + GP  Q G  G   +P   
Sbjct: 658 GEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPG-- 715

Query: 209 VVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKSRGGRG 252
                   G +   G +G    P L G   P  DG P   G  G
Sbjct: 716 ------PQGPIGPPGEKGPQGKPGLAG--LPGADGPPGHPGKEG 751



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 47/167 (28%), Positives = 61/167 (36%), Gaps = 17/167 (10%)

Query: 13   ERGAS-PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPR 71
            E GA  PPG  GP    G +G         +P P     L    G+       G   LP 
Sbjct: 1394 EAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP- 1452

Query: 72   GGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQG--GKSGWLSVPASRG-V 128
                 + D G K + G  G + +   P         G P +QG  G  G   +P   G +
Sbjct: 1453 ---GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPL 1509

Query: 129  APPGAMGILRARGGRGT-GSQSP--------LPASLGVPPPPAMGVQ 166
             PPG  G+   +G +G  GS  P        LP   G P PP   +Q
Sbjct: 1510 GPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQ 1556



 Score = 32.7 bits (73), Expect = 0.32
 Identities = 46/180 (25%), Positives = 63/180 (35%), Gaps = 27/180 (15%)

Query: 87  GKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRG-VAPPGAMGILRARGGRGT 145
           G++G    P++   G   +   GP    G +G +  P  +G   PPG  G       RG 
Sbjct: 435 GEKGQKGEPAVVEPGMLVE---GPPGPAGPAGIMGPPGLQGPTGPPGDPG------DRGP 485

Query: 146 GSQSPLPASLGVPPPPAMGVQRARGGRGVGSESPPRWGCLPTCDG-------------GP 192
             +  LP + G+P PP   +       G GS+ P                        GP
Sbjct: 486 PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGP 545

Query: 193 KSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKSRGGRG 252
               G+ G +  P S         G    +G RGV   P   G    R  G P + GGRG
Sbjct: 546 MGLTGRPGPVGGPGS--SGAKGESGDPGPQGPRGVQGPPGPTGKPGKR--GRPGADGGRG 601


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
           sapiens]
          Length = 1767

 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 80/262 (30%), Positives = 101/262 (38%), Gaps = 44/262 (16%)

Query: 20  GIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAW----GGRGAGSQSLPRGGAS 75
           G+ G K + G+ G+           P   G +  +G R      G RG      P+G A 
Sbjct: 733 GLKGSKGEKGEDGF-----------PGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAG 781

Query: 76  ARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSV---PASRGVA--- 129
              D GP  Q G++G L VP LP G    Q   GPK   G  G+        +RGVA   
Sbjct: 782 PTGDPGPSGQAGEKGKLGVPGLP-GYPGRQ---GPKGSTGFPGFPGANGEKGARGVAGKP 837

Query: 130 -PPGAMGILRARGGRG----TGSQSPLPASLGVPPPPAMGVQRARGGRG-VGSESPPRWG 183
            P G  G    RG RG    TG   P   S G  PP   G +  +G +G VG   P    
Sbjct: 838 GPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPP 897

Query: 184 CLPTCDG-----GPKSQGGKRGWLSVPASWVV----SPTPAMGVLRARGGRGVALSPYLM 234
             P  DG     G + + G +G    P    V     PT   G +  RG  G    P   
Sbjct: 898 GPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQ 957

Query: 235 G--GASPR--CDGDPKSRGGRG 252
           G  GA+ +    GDP  +G  G
Sbjct: 958 GLPGAAGKEGAKGDPGPQGISG 979



 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 81/300 (27%), Positives = 102/300 (34%), Gaps = 76/300 (25%)

Query: 19  PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASARC 78
           PG+ G K   G+ G          P PP    ++   G   G RG   ++ PRG    R 
Sbjct: 567 PGLPGDKGHRGERG------PQGPPGPPGDDGMRGEDGEI-GPRGLPGEAGPRGLLGPRG 619

Query: 79  DGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRG-VAPPGAM--- 134
             G   Q G  G +  P  P+G   PQ + GP  Q G  G   +P  +G + PPG     
Sbjct: 620 TPGAPGQPGMAG-VDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQ 678

Query: 135 ---------GILRARGGRGTGSQSPLPASLGVPPPPA-------MGVQRARGGRGV---- 174
                    G     G  G   QS    +LG P P          GV+ A G RG+    
Sbjct: 679 GKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSK 738

Query: 175 ------------------------------GSESP--PRWGCLPTCDGGPKSQGGKRGWL 202
                                         G + P  P+    PT D GP  Q G++G L
Sbjct: 739 GEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKL 798

Query: 203 SVPA--SWVVSPTPA--------MGVLRARGGRGVALSPYLMGGASPRCDGDPKSRGGRG 252
            VP    +     P          G    +G RGVA  P   G   P   G   SRG RG
Sbjct: 799 GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP--TGPRGSRGARG 856



 Score = 58.5 bits (140), Expect = 5e-09
 Identities = 73/259 (28%), Positives = 94/259 (36%), Gaps = 49/259 (18%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASAR 77
            PPG  GP+   G +G     A     PP ++G +   G +  G  G      P G A   
Sbjct: 1181 PPGPPGPRGPQGPNG-----ADGPQGPPGSVGSVGGVGEK--GEPGEAGNPGPPGEAGV- 1232

Query: 78   CDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQG--GKSGWLSVPASRGVAPPGAMG 135
              GGPK + G++G    P        P   G P   G  G  G +  P   G  PPG  G
Sbjct: 1233 --GGPKGERGEKGEAGPPG---AAGPPGAKGPPGDDGPKGNPGPVGFPGDPG--PPGEPG 1285

Query: 136  ILRARGGRGTGSQSPLPASLGVP----------------PPPAMGVQRARGGRG----VG 175
                 G  G   +   P   G P                PP A G +  +G +G     G
Sbjct: 1286 PAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAG 1345

Query: 176  SESPP-RWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLM 234
            +E PP + G  P    GP  + G  G   +P      P    G+  A G  G    P  M
Sbjct: 1346 AEGPPGKTG--PVGPQGPAGKPGPEGLRGIP-----GPVGEQGLPGAAGQDG---PPGPM 1395

Query: 235  GGAS-PRCDGDPKSRGGRG 252
            G    P   GDP S+G +G
Sbjct: 1396 GPPGLPGLKGDPGSKGEKG 1414



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 64/239 (26%), Positives = 89/239 (37%), Gaps = 17/239 (7%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAW--GGRGAGSQSLPRGGAS 75
            PPG  G K   G+ G    A    V  P  +       G     G +G   +   +G   
Sbjct: 1043 PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG 1102

Query: 76   ARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGV-APPGAM 134
             + + GP    G +G +  P +  G   P    GP+ Q G  G      +RG   PPG +
Sbjct: 1103 DKGENGPPGPPGLQGPVGAPGIAGGDGEP----GPRGQQGMFGQKGDEGARGFPGPPGPI 1158

Query: 135  GILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGV-GSESPPRWGCLPTCDG-GP 192
            G+    G  G   ++     +G P PP  G +  +G  G  G + PP  G + +  G G 
Sbjct: 1159 GLQGLPGPPGEKGENGDVGPMGPPGPP--GPRGPQGPNGADGPQGPP--GSVGSVGGVGE 1214

Query: 193  KSQGGKRGWLSVPA-SWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKSRGG 250
            K + G+ G    P  + V  P    G     G  G A  P   G   P  D  PK   G
Sbjct: 1215 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP---GAKGPPGDDGPKGNPG 1270



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 62/245 (25%), Positives = 82/245 (33%), Gaps = 42/245 (17%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLP--RGGAS 75
            P G+ GP+   G++G          P PP                  G Q LP   G   
Sbjct: 926  PGGVVGPQGPTGETGPIGERGHPGPPGPP------------------GEQGLPGAAGKEG 967

Query: 76   ARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAPPGAMG 135
            A+ D GP+   GK G   +   P     P   G P  +GG+             PPG +G
Sbjct: 968  AKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQ---------GPPGPVG 1018

Query: 136  ILRARGGRGTGSQSPLPASLGVPPPP-------AMGVQRARGGRGVGSESPPRWGCLPTC 188
                RG  GT     LP   G   PP       A G +  +G  G      P     P  
Sbjct: 1019 SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG 1078

Query: 189  DGGPKSQGGKRGWLSVPA-SWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKS 247
              G   + G +G +  P            G     G +G   +P + GG     DG+P  
Sbjct: 1079 PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG-----DGEPGP 1133

Query: 248  RGGRG 252
            RG +G
Sbjct: 1134 RGQQG 1138



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 58/224 (25%), Positives = 73/224 (32%), Gaps = 29/224 (12%)

Query: 44  PPPAMGVL----KARGGRAWGGRGAGSQSLPRGGASARCDGGPKSQGGKRGWLSVPSLPR 99
           PP  MG+        G  + G +G      P+G    +   GP  + GKRG         
Sbjct: 491 PPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD---- 546

Query: 100 GGASPQCDGGPKSQGGKSGWLSVPASRG-------VAPPGAMGILRARGGRGTGSQSPLP 152
           GG     + G K   G  G   +P  +G         PPG  G    RG  G      LP
Sbjct: 547 GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLP 606

Query: 153 ASLG----VPPPPAMGVQRARGGRGVGSESPPRWGCLPTCDGGPKSQGGKRGWLSVPASW 208
              G    + P    G     G  GV     P+    P  + GP  Q G  G   +P   
Sbjct: 607 GEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPG-- 664

Query: 209 VVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKSRGGRG 252
                   G +   G +G    P L G   P  DG P   G  G
Sbjct: 665 ------PQGPIGPPGEKGPQGKPGLAG--LPGADGPPGHPGKEG 700



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 47/167 (28%), Positives = 61/167 (36%), Gaps = 17/167 (10%)

Query: 13   ERGAS-PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPR 71
            E GA  PPG  GP    G +G         +P P     L    G+       G   LP 
Sbjct: 1343 EAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP- 1401

Query: 72   GGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQG--GKSGWLSVPASRG-V 128
                 + D G K + G  G + +   P         G P +QG  G  G   +P   G +
Sbjct: 1402 ---GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPL 1458

Query: 129  APPGAMGILRARGGRGT-GSQSP--------LPASLGVPPPPAMGVQ 166
             PPG  G+   +G +G  GS  P        LP   G P PP   +Q
Sbjct: 1459 GPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQ 1505



 Score = 32.7 bits (73), Expect = 0.32
 Identities = 46/180 (25%), Positives = 63/180 (35%), Gaps = 27/180 (15%)

Query: 87  GKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRG-VAPPGAMGILRARGGRGT 145
           G++G    P++   G   +   GP    G +G +  P  +G   PPG  G       RG 
Sbjct: 384 GEKGQKGEPAVVEPGMLVE---GPPGPAGPAGIMGPPGLQGPTGPPGDPG------DRGP 434

Query: 146 GSQSPLPASLGVPPPPAMGVQRARGGRGVGSESPPRWGCLPTCDG-------------GP 192
             +  LP + G+P PP   +       G GS+ P                        GP
Sbjct: 435 PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGP 494

Query: 193 KSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKSRGGRG 252
               G+ G +  P S         G    +G RGV   P   G    R  G P + GGRG
Sbjct: 495 MGLTGRPGPVGGPGS--SGAKGESGDPGPQGPRGVQGPPGPTGKPGKR--GRPGADGGRG 550


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 80/262 (30%), Positives = 101/262 (38%), Gaps = 44/262 (16%)

Query: 20   GIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAW----GGRGAGSQSLPRGGAS 75
            G+ G K + G+ G+           P   G +  +G R      G RG      P+G A 
Sbjct: 772  GLKGSKGEKGEDGF-----------PGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAG 820

Query: 76   ARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSV---PASRGVA--- 129
               D GP  Q G++G L VP LP G    Q   GPK   G  G+        +RGVA   
Sbjct: 821  PTGDPGPSGQAGEKGKLGVPGLP-GYPGRQ---GPKGSTGFPGFPGANGEKGARGVAGKP 876

Query: 130  -PPGAMGILRARGGRG----TGSQSPLPASLGVPPPPAMGVQRARGGRG-VGSESPPRWG 183
             P G  G    RG RG    TG   P   S G  PP   G +  +G +G VG   P    
Sbjct: 877  GPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPP 936

Query: 184  CLPTCDG-----GPKSQGGKRGWLSVPASWVV----SPTPAMGVLRARGGRGVALSPYLM 234
              P  DG     G + + G +G    P    V     PT   G +  RG  G    P   
Sbjct: 937  GPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQ 996

Query: 235  G--GASPR--CDGDPKSRGGRG 252
            G  GA+ +    GDP  +G  G
Sbjct: 997  GLPGAAGKEGAKGDPGPQGISG 1018



 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 81/300 (27%), Positives = 102/300 (34%), Gaps = 76/300 (25%)

Query: 19  PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASARC 78
           PG+ G K   G+ G          P PP    ++   G   G RG   ++ PRG    R 
Sbjct: 606 PGLPGDKGHRGERG------PQGPPGPPGDDGMRGEDGEI-GPRGLPGEAGPRGLLGPRG 658

Query: 79  DGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRG-VAPPGAM--- 134
             G   Q G  G +  P  P+G   PQ + GP  Q G  G   +P  +G + PPG     
Sbjct: 659 TPGAPGQPGMAG-VDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQ 717

Query: 135 ---------GILRARGGRGTGSQSPLPASLGVPPPPA-------MGVQRARGGRGV---- 174
                    G     G  G   QS    +LG P P          GV+ A G RG+    
Sbjct: 718 GKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSK 777

Query: 175 ------------------------------GSESP--PRWGCLPTCDGGPKSQGGKRGWL 202
                                         G + P  P+    PT D GP  Q G++G L
Sbjct: 778 GEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKL 837

Query: 203 SVPA--SWVVSPTPA--------MGVLRARGGRGVALSPYLMGGASPRCDGDPKSRGGRG 252
            VP    +     P          G    +G RGVA  P   G   P   G   SRG RG
Sbjct: 838 GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP--TGPRGSRGARG 895



 Score = 58.5 bits (140), Expect = 5e-09
 Identities = 73/259 (28%), Positives = 94/259 (36%), Gaps = 49/259 (18%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASAR 77
            PPG  GP+   G +G     A     PP ++G +   G +  G  G      P G A   
Sbjct: 1220 PPGPPGPRGPQGPNG-----ADGPQGPPGSVGSVGGVGEK--GEPGEAGNPGPPGEAGV- 1271

Query: 78   CDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQG--GKSGWLSVPASRGVAPPGAMG 135
              GGPK + G++G    P        P   G P   G  G  G +  P   G  PPG  G
Sbjct: 1272 --GGPKGERGEKGEAGPPG---AAGPPGAKGPPGDDGPKGNPGPVGFPGDPG--PPGEPG 1324

Query: 136  ILRARGGRGTGSQSPLPASLGVP----------------PPPAMGVQRARGGRG----VG 175
                 G  G   +   P   G P                PP A G +  +G +G     G
Sbjct: 1325 PAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAG 1384

Query: 176  SESPP-RWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLM 234
            +E PP + G  P    GP  + G  G   +P      P    G+  A G  G    P  M
Sbjct: 1385 AEGPPGKTG--PVGPQGPAGKPGPEGLRGIP-----GPVGEQGLPGAAGQDG---PPGPM 1434

Query: 235  GGAS-PRCDGDPKSRGGRG 252
            G    P   GDP S+G +G
Sbjct: 1435 GPPGLPGLKGDPGSKGEKG 1453



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 64/239 (26%), Positives = 89/239 (37%), Gaps = 17/239 (7%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAW--GGRGAGSQSLPRGGAS 75
            PPG  G K   G+ G    A    V  P  +       G     G +G   +   +G   
Sbjct: 1082 PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG 1141

Query: 76   ARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGV-APPGAM 134
             + + GP    G +G +  P +  G   P    GP+ Q G  G      +RG   PPG +
Sbjct: 1142 DKGENGPPGPPGLQGPVGAPGIAGGDGEP----GPRGQQGMFGQKGDEGARGFPGPPGPI 1197

Query: 135  GILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGV-GSESPPRWGCLPTCDG-GP 192
            G+    G  G   ++     +G P PP  G +  +G  G  G + PP  G + +  G G 
Sbjct: 1198 GLQGLPGPPGEKGENGDVGPMGPPGPP--GPRGPQGPNGADGPQGPP--GSVGSVGGVGE 1253

Query: 193  KSQGGKRGWLSVPA-SWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKSRGG 250
            K + G+ G    P  + V  P    G     G  G A  P   G   P  D  PK   G
Sbjct: 1254 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP---GAKGPPGDDGPKGNPG 1309



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 62/245 (25%), Positives = 82/245 (33%), Gaps = 42/245 (17%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLP--RGGAS 75
            P G+ GP+   G++G          P PP                  G Q LP   G   
Sbjct: 965  PGGVVGPQGPTGETGPIGERGHPGPPGPP------------------GEQGLPGAAGKEG 1006

Query: 76   ARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAPPGAMG 135
            A+ D GP+   GK G   +   P     P   G P  +GG+             PPG +G
Sbjct: 1007 AKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQ---------GPPGPVG 1057

Query: 136  ILRARGGRGTGSQSPLPASLGVPPPP-------AMGVQRARGGRGVGSESPPRWGCLPTC 188
                RG  GT     LP   G   PP       A G +  +G  G      P     P  
Sbjct: 1058 SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG 1117

Query: 189  DGGPKSQGGKRGWLSVPA-SWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKS 247
              G   + G +G +  P            G     G +G   +P + GG     DG+P  
Sbjct: 1118 PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG-----DGEPGP 1172

Query: 248  RGGRG 252
            RG +G
Sbjct: 1173 RGQQG 1177



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 58/224 (25%), Positives = 73/224 (32%), Gaps = 29/224 (12%)

Query: 44  PPPAMGVL----KARGGRAWGGRGAGSQSLPRGGASARCDGGPKSQGGKRGWLSVPSLPR 99
           PP  MG+        G  + G +G      P+G    +   GP  + GKRG         
Sbjct: 530 PPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD---- 585

Query: 100 GGASPQCDGGPKSQGGKSGWLSVPASRG-------VAPPGAMGILRARGGRGTGSQSPLP 152
           GG     + G K   G  G   +P  +G         PPG  G    RG  G      LP
Sbjct: 586 GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLP 645

Query: 153 ASLG----VPPPPAMGVQRARGGRGVGSESPPRWGCLPTCDGGPKSQGGKRGWLSVPASW 208
              G    + P    G     G  GV     P+    P  + GP  Q G  G   +P   
Sbjct: 646 GEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPG-- 703

Query: 209 VVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKSRGGRG 252
                   G +   G +G    P L G   P  DG P   G  G
Sbjct: 704 ------PQGPIGPPGEKGPQGKPGLAG--LPGADGPPGHPGKEG 739



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 47/167 (28%), Positives = 61/167 (36%), Gaps = 17/167 (10%)

Query: 13   ERGAS-PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPR 71
            E GA  PPG  GP    G +G         +P P     L    G+       G   LP 
Sbjct: 1382 EAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP- 1440

Query: 72   GGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQG--GKSGWLSVPASRG-V 128
                 + D G K + G  G + +   P         G P +QG  G  G   +P   G +
Sbjct: 1441 ---GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPL 1497

Query: 129  APPGAMGILRARGGRGT-GSQSP--------LPASLGVPPPPAMGVQ 166
             PPG  G+   +G +G  GS  P        LP   G P PP   +Q
Sbjct: 1498 GPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQ 1544



 Score = 32.7 bits (73), Expect = 0.32
 Identities = 46/180 (25%), Positives = 63/180 (35%), Gaps = 27/180 (15%)

Query: 87  GKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRG-VAPPGAMGILRARGGRGT 145
           G++G    P++   G   +   GP    G +G +  P  +G   PPG  G       RG 
Sbjct: 423 GEKGQKGEPAVVEPGMLVE---GPPGPAGPAGIMGPPGLQGPTGPPGDPG------DRGP 473

Query: 146 GSQSPLPASLGVPPPPAMGVQRARGGRGVGSESPPRWGCLPTCDG-------------GP 192
             +  LP + G+P PP   +       G GS+ P                        GP
Sbjct: 474 PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGP 533

Query: 193 KSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKSRGGRG 252
               G+ G +  P S         G    +G RGV   P   G    R  G P + GGRG
Sbjct: 534 MGLTGRPGPVGGPGS--SGAKGESGDPGPQGPRGVQGPPGPTGKPGKR--GRPGADGGRG 589


>gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo
            sapiens]
          Length = 2971

 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 54/191 (28%), Positives = 73/191 (38%), Gaps = 7/191 (3%)

Query: 13   ERGASPPGIGGPKSQWGKSGWFSIAASWRVPPPPA-MGVLKARG-GRAWGGRGAGSQSLP 70
            ERG  PPG+ G +   G  G   +  S   P     +G +   G     G +G    S  
Sbjct: 1866 ERG--PPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGE 1923

Query: 71   RGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAP 130
            +G    R D GP+ + G+RG + +   P        + GPK + G  G + VP   GV  
Sbjct: 1924 KGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGV-- 1981

Query: 131  PGAMGILRARGGRGTGSQSPLPASLGVPPPPAM-GVQRARGGRGVGSESPPRWGCLPTCD 189
            PG  G     GG G         + G P  P   G Q  RG +G    + P         
Sbjct: 1982 PGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGI 2041

Query: 190  GGPKSQGGKRG 200
             GP+  GG  G
Sbjct: 2042 SGPRGSGGAAG 2052


>gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
            sapiens]
          Length = 3177

 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 54/191 (28%), Positives = 73/191 (38%), Gaps = 7/191 (3%)

Query: 13   ERGASPPGIGGPKSQWGKSGWFSIAASWRVPPPPA-MGVLKARG-GRAWGGRGAGSQSLP 70
            ERG  PPG+ G +   G  G   +  S   P     +G +   G     G +G    S  
Sbjct: 2072 ERG--PPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGE 2129

Query: 71   RGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAP 130
            +G    R D GP+ + G+RG + +   P        + GPK + G  G + VP   GV  
Sbjct: 2130 KGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGV-- 2187

Query: 131  PGAMGILRARGGRGTGSQSPLPASLGVPPPPAM-GVQRARGGRGVGSESPPRWGCLPTCD 189
            PG  G     GG G         + G P  P   G Q  RG +G    + P         
Sbjct: 2188 PGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGI 2247

Query: 190  GGPKSQGGKRG 200
             GP+  GG  G
Sbjct: 2248 SGPRGSGGAAG 2258


>gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo
            sapiens]
          Length = 2570

 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 54/191 (28%), Positives = 73/191 (38%), Gaps = 7/191 (3%)

Query: 13   ERGASPPGIGGPKSQWGKSGWFSIAASWRVPPPPA-MGVLKARG-GRAWGGRGAGSQSLP 70
            ERG  PPG+ G +   G  G   +  S   P     +G +   G     G +G    S  
Sbjct: 1465 ERG--PPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGE 1522

Query: 71   RGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAP 130
            +G    R D GP+ + G+RG + +   P        + GPK + G  G + VP   GV  
Sbjct: 1523 KGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGV-- 1580

Query: 131  PGAMGILRARGGRGTGSQSPLPASLGVPPPPAM-GVQRARGGRGVGSESPPRWGCLPTCD 189
            PG  G     GG G         + G P  P   G Q  RG +G    + P         
Sbjct: 1581 PGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGI 1640

Query: 190  GGPKSQGGKRG 200
             GP+  GG  G
Sbjct: 1641 SGPRGSGGAAG 1651


>gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens]
          Length = 1712

 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 80/277 (28%), Positives = 104/277 (37%), Gaps = 52/277 (18%)

Query: 18  PPGIGGPKSQWGKSGW-FSI-AASWRVPPPPAMGVLKARGGRAWGGRGA------GSQSL 69
           PPG+ GP    G  G+ F +  A  R   P   G   ARG + W G         G +++
Sbjct: 436 PPGLPGPP---GPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAI 492

Query: 70  --------PRGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDG--GPKSQGGKSGW 119
                   P+G A    + G K   G  G   +P  P     P   G  GPK   G S  
Sbjct: 493 KGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRT 552

Query: 120 LSVPASRGVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGV----- 174
           ++    RG   PG  G+   +G  G+  +  L    G+P PP  G++   G  G      
Sbjct: 553 ITTKGERG--QPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPG 610

Query: 175 -----GSESPPRWGCLPTCDGGPKSQGGKRG--WLSVPASWVVSPTPA---------MGV 218
                G   PP  G LP    G K Q G  G   L  P  ++  P PA           V
Sbjct: 611 TKGTPGEMGPPGLG-LP----GLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDV 665

Query: 219 LRARGG-RGVALSPYLMGGAS--PRCDGDPKSRGGRG 252
            RA GG R  A+ P  +GG    P   G P   G +G
Sbjct: 666 KRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKG 702



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 68/252 (26%), Positives = 88/252 (34%), Gaps = 37/252 (14%)

Query: 18  PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASAR 77
           PPG+G P    G  G         +P PP  G L   G     G+      + R     R
Sbjct: 620 PPGLGLP----GLKGQRGFPGDAGLPGPP--GFLGPPGPAGTPGQIDCDTDVKRAVGGDR 673

Query: 78  -------CDGGPKSQGGKRGWLSVPSLPRGGASPQ-------CDGGPKSQG--GKSGWLS 121
                  C GGPK   G  G    P  P G    +        DGGP  +G  G +G   
Sbjct: 674 QEAIQPGCIGGPKGLPGLPG----PPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREG 729

Query: 122 VPASRGVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGVGSESPPR 181
            P      PPG +G   ++G  G       P  +G+P P     +R   G  +G++  PR
Sbjct: 730 FPG-----PPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPR 784

Query: 182 WGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGG-RGVALSPYLMGGASPR 240
                    G K   G RG    P        P M  L+ + G  G +  P L G   P 
Sbjct: 785 GDAGVPGQPGLKGLPGDRG---PPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYG--PPG 839

Query: 241 CDGDPKSRGGRG 252
             G P + G  G
Sbjct: 840 LHGFPGAPGQEG 851



 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 67/265 (25%), Positives = 91/265 (34%), Gaps = 58/265 (21%)

Query: 13  ERGASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRG 72
           ERGA  PG+ GPK   G  G      +  +P  P  G  + R G               G
Sbjct: 92  ERGA--PGVTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGY-------------DG 136

Query: 73  GASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWL-SVPASRGVAPP 131
               + D GP+   G  G+   P        PQ   GPK Q G+   L      R    P
Sbjct: 137 CNGTQGDSGPQGPPGSEGFTGPP-------GPQ---GPKGQKGEPYALPKEERDRYRGEP 186

Query: 132 GAMGILRARGGRG----TGSQSPLPASLGVPPPPAMGVQRARGGRGVGSESPPRWGCLPT 187
           G  G++  +G  G     G   P+ A     PP   G +  +G RG+G            
Sbjct: 187 GEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKG------ 240

Query: 188 CDGGPKSQGGKRGWLSVPASWVVSPT------------------PAMGVLRARGGRGVAL 229
            + G   Q G  G  S     +++PT                  P +  +  +G  G+  
Sbjct: 241 -EKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMG 299

Query: 230 SPYLMG--GASPRCDGDPKSRGGRG 252
            P L G  G S    G P  +G RG
Sbjct: 300 FPGLRGYPGLSGE-KGSPGQKGSRG 323



 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 48/197 (24%), Positives = 66/197 (33%), Gaps = 36/197 (18%)

Query: 60  GGRGAGSQSLPRGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGW 119
           G +G+  Q   RG    +   GP+   G+ G    P LP     P    G +   G  G 
Sbjct: 311 GEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGA 370

Query: 120 LSVPASRGVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGVGSESP 179
              P S+G                        P   G+P PP + +      RG+  E  
Sbjct: 371 QGEPGSQGE-----------------------PGDPGLPGPPGLSIGDGDQRRGLPGEMG 407

Query: 180 PRWGC----LPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMG 235
           P+       +P   GGP    GKRG    P      P P   +   +G +G A       
Sbjct: 408 PKGFIGDPGIPALYGGPPGPDGKRG-PPGPPGLPGPPGPDGFLFGLKGAKGRA------- 459

Query: 236 GASPRCDGDPKSRGGRG 252
              P   G P +RG +G
Sbjct: 460 -GFPGLPGSPGARGPKG 475



 Score = 36.2 bits (82), Expect = 0.029
 Identities = 49/179 (27%), Positives = 63/179 (35%), Gaps = 14/179 (7%)

Query: 87   GKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAP-PGAMGILRARGGRGT 145
            G  G    P L      P   G P SQG + G + +P  +G    PGA G+    G RG 
Sbjct: 1137 GVTGVQGPPGLKGQTGFPGLTGPPGSQG-ELGRIGLPGGKGDDGWPGAPGLPGFPGLRGI 1195

Query: 146  GSQSPLPASLGVPPPPAMGVQRARGGRGVGSE--SPPRWGCLPTCDGGPKSQG-----GK 198
                 LP + G P  P   +    G  G   E   P     LP   G P  +G     G+
Sbjct: 1196 RGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGE 1255

Query: 199  RGWLSVPA----SWVVSPTPAMGVLRARGGRGV-ALSPYLMGGASPRCDGDPKSRGGRG 252
            RG    P       +  P+   G    +G  G+  L  Y      P     P S+G  G
Sbjct: 1256 RGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTG 1314



 Score = 32.0 bits (71), Expect = 0.54
 Identities = 63/276 (22%), Positives = 95/276 (34%), Gaps = 60/276 (21%)

Query: 19   PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASARC 78
            PG  G K   G++G+F I     +   P       +G R   G       +  G    + 
Sbjct: 940  PGFPGSK---GEAGFFGIPGLKGLAGEPGF-----KGSRGDPGPPGPPPVILPGMKDIKG 991

Query: 79   DGGPKSQGGKRGWLS------VPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGV---- 128
            + G +   G +G+L       +P +P     P   G P    G  G + VP   G+    
Sbjct: 992  EKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFP 1051

Query: 129  ---APPGAM---GILRARGGRGTGSQSPLPASLG-----------VPPPPAMGVQRARGG 171
                PPG     G + +RG +G   ++ L   +G           +  P   G++  RG 
Sbjct: 1052 GVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGT 1111

Query: 172  RGV----------GSESPPRWGCLPTCDG-----GPKSQGGKRGWLSVPASWVVSPTPAM 216
             G+          G+E    +  +    G     G K Q G  G    P S        +
Sbjct: 1112 TGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGS-----QGEL 1166

Query: 217  GVLRARGGRGVALSPYLMGGASPRCDGDPKSRGGRG 252
            G +   GG+G    P      +P   G P  RG RG
Sbjct: 1167 GRIGLPGGKGDDGWP-----GAPGLPGFPGLRGIRG 1197


>gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo
           sapiens]
          Length = 921

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 71/250 (28%), Positives = 94/250 (37%), Gaps = 34/250 (13%)

Query: 18  PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASAR 77
           PPG  GPK   G  G   I     +P P     L    GR       G   +P G     
Sbjct: 509 PPGEAGPKGDRGAEGARGIPG---LPGPKGDTGLPGVDGRD------GIPGMP-GTKGEP 558

Query: 78  CDGGPKSQGGKRGWLSVPSLP--RGGASPQCDGGPKSQGGKSGWLSVPASRG----VAPP 131
              GP    G +G   VP +P  +G A  +   G   + G+ G    P  +G    V P 
Sbjct: 559 GKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPR 618

Query: 132 GAMGILRARGGRGTGSQSPLPASLG---------VPPPPAMGVQRARGGRGVGSESPPRW 182
           G  G+  +RG  G      LP  LG         +P PP  G+   +G RGV  E  P+ 
Sbjct: 619 GPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPP--GLPGMKGDRGVVGEPGPKG 676

Query: 183 GCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCD 242
               + + G   + G+ G + +P      P  + G     G RG   S  L G   PR  
Sbjct: 677 EQGASGEEGEAGERGELGDIGLP-----GPKGSAGNPGEPGLRGPEGSRGLPGVEGPR-- 729

Query: 243 GDPKSRGGRG 252
           G P  RG +G
Sbjct: 730 GPPGPRGVQG 739



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 73/268 (27%), Positives = 85/268 (31%), Gaps = 55/268 (20%)

Query: 10  TVEERGASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSL 69
           T +ERG  PPG  GP    G              PP   G+    G R            
Sbjct: 264 TTDERG--PPGEQGPPGPPG--------------PPGVPGIDGIDGDRG----------- 296

Query: 70  PRGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQG--GKSGWLSVPASRG 127
           P+G        GP  + GK G    P  P        DG P S G  G+ G   VP SRG
Sbjct: 297 PKGPPGPP---GPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRG 353

Query: 128 V------APPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGVGSESPPR 181
                   PPG  G     G  G       P   G P PP     R   G   G    P 
Sbjct: 354 FPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPN 413

Query: 182 WGCLPTCDGGPKSQG-----GKRGWLSVPA----------SWVVSPTPAMGVLRARGGRG 226
             C P   G P   G     G +G +  P              +    A G   A+G RG
Sbjct: 414 -ACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRG 472

Query: 227 VALSPYLMGGASPR-CDGDPKSRGGRGA 253
           +       G    R  DG+P  +G  GA
Sbjct: 473 ITGIVGDKGEKGARGLDGEPGPQGLPGA 500



 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 77/293 (26%), Positives = 94/293 (32%), Gaps = 66/293 (22%)

Query: 19  PGIGGPKSQWGKSG-----WFSIAASWRVPPPPAMGVLKARGGRAW-----GGRGAGSQS 68
           PG  G K Q G+ G      F        P PP    L    GR       G RG     
Sbjct: 334 PGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPP 393

Query: 69  LPRG--GASARCDGGPKSQG----GKRGWLSVPSL-----PRGGASPQCDGGPKSQGGKS 117
            P G  G     DG P        G+ G+  +P +      +G        G K + G  
Sbjct: 394 GPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQ 453

Query: 118 GWLSVPASRGVAPPGAMG------ILRARGGRGTGSQSPLPASLGVPPPPAMGVQR---- 167
           G L    ++G  PPGA G      I+  +G +G       P   G+P  P    QR    
Sbjct: 454 GELGEVGAQG--PPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPG 511

Query: 168 ---------ARGGRGV-GSESPPRWGCLPTCDG-----------------GPKSQGGKRG 200
                    A G RG+ G   P     LP  DG                 GP    G +G
Sbjct: 512 EAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQG 571

Query: 201 WLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGA-SPRCDGDPKSRGGRG 252
              VP         A GV   +G  G    P  MG +  P   G P   G RG
Sbjct: 572 LPGVPGI-----PGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRG 619



 Score = 41.2 bits (95), Expect = 9e-04
 Identities = 32/106 (30%), Positives = 44/106 (41%), Gaps = 11/106 (10%)

Query: 100 GGASPQCDGGPKSQGGKSGWLSVPASRGV-APPGAMGI------LRARGGRGTGSQSP-- 150
           G   P    GP  + G  G + +    G+  PPGA+G+      L  +G RG   + P  
Sbjct: 793 GRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNG 852

Query: 151 LPASLGVPPPPAMGVQRARGGRGVGSESPPRWGCLPTCDGGPKSQG 196
           LP ++G+P  P       R GR  G   PP    +P   G P   G
Sbjct: 853 LPGAIGLPGDPG-PASYGRNGRD-GERGPPGVAGIPGVPGPPGPPG 896


>gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo
           sapiens]
          Length = 678

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 71/250 (28%), Positives = 94/250 (37%), Gaps = 34/250 (13%)

Query: 18  PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASAR 77
           PPG  GPK   G  G   I     +P P     L    GR       G   +P G     
Sbjct: 266 PPGEAGPKGDRGAEGARGIPG---LPGPKGDTGLPGVDGRD------GIPGMP-GTKGEP 315

Query: 78  CDGGPKSQGGKRGWLSVPSLP--RGGASPQCDGGPKSQGGKSGWLSVPASRG----VAPP 131
              GP    G +G   VP +P  +G A  +   G   + G+ G    P  +G    V P 
Sbjct: 316 GKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPR 375

Query: 132 GAMGILRARGGRGTGSQSPLPASLG---------VPPPPAMGVQRARGGRGVGSESPPRW 182
           G  G+  +RG  G      LP  LG         +P PP  G+   +G RGV  E  P+ 
Sbjct: 376 GPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPP--GLPGMKGDRGVVGEPGPKG 433

Query: 183 GCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCD 242
               + + G   + G+ G + +P      P  + G     G RG   S  L G   PR  
Sbjct: 434 EQGASGEEGEAGERGELGDIGLP-----GPKGSAGNPGEPGLRGPEGSRGLPGVEGPR-- 486

Query: 243 GDPKSRGGRG 252
           G P  RG +G
Sbjct: 487 GPPGPRGVQG 496



 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 77/293 (26%), Positives = 94/293 (32%), Gaps = 66/293 (22%)

Query: 19  PGIGGPKSQWGKSG-----WFSIAASWRVPPPPAMGVLKARGGRAW-----GGRGAGSQS 68
           PG  G K Q G+ G      F        P PP    L    GR       G RG     
Sbjct: 91  PGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPP 150

Query: 69  LPRG--GASARCDGGPKSQG----GKRGWLSVPSL-----PRGGASPQCDGGPKSQGGKS 117
            P G  G     DG P        G+ G+  +P +      +G        G K + G  
Sbjct: 151 GPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQ 210

Query: 118 GWLSVPASRGVAPPGAMG------ILRARGGRGTGSQSPLPASLGVPPPPAMGVQR---- 167
           G L    ++G  PPGA G      I+  +G +G       P   G+P  P    QR    
Sbjct: 211 GELGEVGAQG--PPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPG 268

Query: 168 ---------ARGGRGV-GSESPPRWGCLPTCDG-----------------GPKSQGGKRG 200
                    A G RG+ G   P     LP  DG                 GP    G +G
Sbjct: 269 EAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQG 328

Query: 201 WLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGA-SPRCDGDPKSRGGRG 252
              VP         A GV   +G  G    P  MG +  P   G P   G RG
Sbjct: 329 LPGVPGI-----PGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRG 376



 Score = 41.2 bits (95), Expect = 9e-04
 Identities = 32/106 (30%), Positives = 44/106 (41%), Gaps = 11/106 (10%)

Query: 100 GGASPQCDGGPKSQGGKSGWLSVPASRGV-APPGAMGI------LRARGGRGTGSQSP-- 150
           G   P    GP  + G  G + +    G+  PPGA+G+      L  +G RG   + P  
Sbjct: 550 GRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNG 609

Query: 151 LPASLGVPPPPAMGVQRARGGRGVGSESPPRWGCLPTCDGGPKSQG 196
           LP ++G+P  P       R GR  G   PP    +P   G P   G
Sbjct: 610 LPGAIGLPGDPG-PASYGRNGRD-GERGPPGVAGIPGVPGPPGPPG 653



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 56/197 (28%), Positives = 65/197 (32%), Gaps = 25/197 (12%)

Query: 81  GPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQG--GKSGWLSVPASRGV------APPG 132
           GP  + GK G    P  P        DG P S G  G+ G   VP SRG        PPG
Sbjct: 62  GPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPG 121

Query: 133 AMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGVGSESPPRWGCLPTCDGGP 192
             G     G  G       P   G P PP     R   G   G    P   C P   G P
Sbjct: 122 PPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPN-ACPPGRSGYP 180

Query: 193 KSQG-----GKRGWLSVPA----------SWVVSPTPAMGVLRARGGRGVALSPYLMGGA 237
              G     G +G +  P              +    A G   A+G RG+       G  
Sbjct: 181 GLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEK 240

Query: 238 SPR-CDGDPKSRGGRGA 253
             R  DG+P  +G  GA
Sbjct: 241 GARGLDGEPGPQGLPGA 257



 Score = 36.6 bits (83), Expect = 0.022
 Identities = 45/143 (31%), Positives = 51/143 (35%), Gaps = 19/143 (13%)

Query: 112 SQGGKSGWLSVPASRGVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGG 171
           +Q G  G    P   G  PPG  GI    G RG       P   G P  P  G     G 
Sbjct: 23  AQRGPPGEQGPPGPPG--PPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKP--GAPGKPGT 78

Query: 172 RGVGSESPPRWGCLPTCDGGPKSQG--GKRGWLSVPASWVVSPTPAMGVLRARGGRGVAL 229
            G    + P        DG P S G  G++G   VP S      P  G+    G  G A 
Sbjct: 79  PGADGLTGP--------DGSPGSIGSKGQKGEPGVPGS---RGFPGRGIPGPPGPPGTAG 127

Query: 230 SPYLMGGASPRCDGDPKSRGGRG 252
            P  +G   P   GDP  RG  G
Sbjct: 128 LPGELGRVGP--VGDPGRRGPPG 148


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 75/266 (28%), Positives = 90/266 (33%), Gaps = 39/266 (14%)

Query: 18   PPGIGGPKSQWGKSGWFSI-AASWRVPPPPAMGVLKARGGRAWGG----RGAGSQSLPRG 72
            PPG  G +   G  G      A+ R  PP   G+    G     G    RG      P G
Sbjct: 770  PPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVG 829

Query: 73   GASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRG----- 127
                    GP    G++G    PS   G A P    GP+   G  G L +P SRG     
Sbjct: 830  RTGEVGAVGPPGFAGEKG----PSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLP 885

Query: 128  -----VAPPGAMGILRARGGRGTGSQSPLPASLGVP-------------PPPAMGVQRAR 169
                 V  PG +GI    G RG       P   G P             PP   G    +
Sbjct: 886  GVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHK 945

Query: 170  GGRGV-GSESPPRWGCLPTCDG--GPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRG 226
            G RG  G+  P      P   G  GP  + G RG      S  V P  A+G     G +G
Sbjct: 946  GERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRG--ETGPSGPVGPAGAVGPRGPSGPQG 1003

Query: 227  VALSPYLMGGASPRCDGDPKSRGGRG 252
            +       G   PR  G P  +G  G
Sbjct: 1004 IRGDKGEPGEKGPR--GLPGLKGHNG 1027



 Score = 54.7 bits (130), Expect = 8e-08
 Identities = 78/264 (29%), Positives = 97/264 (36%), Gaps = 35/264 (13%)

Query: 12  EERGASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAM-GVLKARG-----GRA--WGGRG 63
           E   A P G  GP  + GK G    A S   P PP + G   +RG     GRA   G  G
Sbjct: 362 EPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPG 421

Query: 64  AGSQSLPRGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGP---KSQGGKSGWL 120
           +   S P G      D G   + G  G   +P  P G   P    GP       G+ G +
Sbjct: 422 SRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSP-GNIGPAGKEGPVGLPGIDGRPGPI 480

Query: 121 SVPASRG----VAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPA-------MGVQRAR 169
               +RG    +  PG  G     G  G    + L  + G P P          G Q  +
Sbjct: 481 GPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQ 540

Query: 170 GGRG-VGSESPPRWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVA 228
           GG+G  G   PP +  LP    GP  + GK G   +   + + P PA       G RG  
Sbjct: 541 GGKGEQGPPGPPGFQGLPG-PSGPAGEVGKPGERGLHGEFGL-PGPA-------GPRGER 591

Query: 229 LSPYLMGGASPRCDGDPKSRGGRG 252
             P   G A P   G   SRG  G
Sbjct: 592 GPPGESGAAGP--TGPIGSRGPSG 613



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 65/208 (31%), Positives = 81/208 (38%), Gaps = 35/208 (16%)

Query: 70  PRGGASARCDGGPKSQGGKRGWLSVPSL--PRGG-ASPQCDGGPKSQG-----GKSGWLS 121
           P+G   A  + GP    G RG + +P L  P G   +P  +G   ++G     G +G   
Sbjct: 263 PKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPG 322

Query: 122 VPASRGV-APPGAMGILRARG---------GRGTGSQSPLPASLGVPPPPA-MGVQRARG 170
           +P  RG+  P GA G   ARG          +G       P S G   PP   G +  RG
Sbjct: 323 LPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRG 382

Query: 171 GRG-VGSESPPRWGCLPTCDGGPKSQG-----GKRGWLSVPASWVVSPTPAMGVLRARGG 224
             G  GS  PP     P   G P S+G     G+ G +  P S       A G    RG 
Sbjct: 383 PNGEAGSAGPPG---PPGLRGSPGSRGLPGADGRAGVMGPPGS-----RGASGPAGVRGP 434

Query: 225 RGVALSPYLMGGASPRCDGDPKSRGGRG 252
            G A  P   G   PR  G P S G  G
Sbjct: 435 NGDAGRPGEPGLMGPR--GLPGSPGNIG 460



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 72/249 (28%), Positives = 90/249 (36%), Gaps = 40/249 (16%)

Query: 19  PGIGGPKSQWGKSG---WFSIAASWRVPPPPAMGVLKARGGR--AWGGRGAGSQSLPRGG 73
           PG  GP    GK+G      +A +   P P      +   G     GG+G      P G 
Sbjct: 495 PGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGF 554

Query: 74  ASARCDGGPKSQGGK---RGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAP 130
                  GP  + GK   RG      LP G A P+ + GP  + G +G      SRG + 
Sbjct: 555 QGLPGPSGPAGEVGKPGERGLHGEFGLP-GPAGPRGERGPPGESGAAGPTGPIGSRGPSG 613

Query: 131 P-------GAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGVGSESPPRWG 183
           P       G  G++ A G  G    S LP   G    P        GG+G   E   R  
Sbjct: 614 PPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIP--------GGKGEKGEPGLR-- 663

Query: 184 CLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDG 243
                  G     G+ G    P + V +P PA     A G RG A +    G A PR  G
Sbjct: 664 -------GEIGNPGRDGARGAPGA-VGAPGPA----GATGDRGEAGAAGPAGPAGPR--G 709

Query: 244 DPKSRGGRG 252
            P  RG  G
Sbjct: 710 SPGERGEVG 718



 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 67/247 (27%), Positives = 86/247 (34%), Gaps = 48/247 (19%)

Query: 16   ASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGG-RGAGSQSLPRGGA 74
            A PPG  GP+   G               P  +G+  +RG R   G  GA  +  P G A
Sbjct: 855  AGPPGTPGPQGLLG--------------APGILGLPGSRGERGLPGVAGAVGEPGPLGIA 900

Query: 75   SARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQG-----GKSGWLS----VPAS 125
                  GP    G  G    P       +P  DG P   G     G+ G+      V A+
Sbjct: 901  GPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAA 960

Query: 126  RGVAPPGAMGILRARGGRG-TGSQSPLPASLGVPPPPAMGVQRARGGRGVGSESPPRWGC 184
                P G +G     G RG TG   P+  +  V P    G Q  RG +G   E  PR   
Sbjct: 961  GAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRG-- 1018

Query: 185  LPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGD 244
            LP    G K   G +G                G+    G +G   +P  +G A PR    
Sbjct: 1019 LP----GLKGHNGLQG--------------LPGIAGHHGDQG---APGSVGPAGPRGPAG 1057

Query: 245  PKSRGGR 251
            P    G+
Sbjct: 1058 PSGPAGK 1064



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 66/251 (26%), Positives = 79/251 (31%), Gaps = 19/251 (7%)

Query: 16  ASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGG--RAWGGRG-AGSQSLP-- 70
           A P G  GP  + G +G      S     PP     K   G   A G  G +G   LP  
Sbjct: 585 AGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGE 644

Query: 71  RGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAP 130
           RG A      G K + G RG +  P       +P   G P   G         A+    P
Sbjct: 645 RGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGP 704

Query: 131 PGAMGILRARGGRGTGSQSPLPASLGVPPPPA----MGVQRARGGRGVGSESPPRWGCLP 186
            G  G    RG  G    +      G    P      G +  +G  GV   + P     P
Sbjct: 705 AGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGP 764

Query: 187 TCDGGPKSQGGKRGWLSVP-------ASWVVSPTPAMGVLRARGGRGVALSPYLMGGASP 239
               GP    G RG    P       A+    P    G+    G  G A    L G   P
Sbjct: 765 AGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRG---P 821

Query: 240 RCDGDPKSRGG 250
           R D  P  R G
Sbjct: 822 RGDQGPVGRTG 832



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 53/192 (27%), Positives = 69/192 (35%), Gaps = 29/192 (15%)

Query: 16  ASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGAS 75
           A  PG+ GP+   G  G      +  +   P     K   G     +G    + P+G   
Sbjct: 318 AGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGN----KGEPGSAGPQG--- 370

Query: 76  ARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRG----VAPP 131
                GP  + GKRG       P G A      GP    G  G   +P + G    + PP
Sbjct: 371 ---PPGPSGEEGKRG-------PNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPP 420

Query: 132 GAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRG-VGSESPPRWGCLPTCDG 190
           G+ G     G RG    +  P   G+  P   G+  + G  G  G E P     LP  DG
Sbjct: 421 GSRGASGPAGVRGPNGDAGRPGEPGLMGP--RGLPGSPGNIGPAGKEGPVG---LPGIDG 475

Query: 191 --GPKSQGGKRG 200
             GP    G RG
Sbjct: 476 RPGPIGPAGARG 487



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 65/252 (25%), Positives = 84/252 (33%), Gaps = 43/252 (17%)

Query: 18  PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASAR 77
           P G  GP    G+ G          P PP    L       + G+G G            
Sbjct: 40  PRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVG------------ 87

Query: 78  CDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVA-------- 129
              GP    G RG    P    G   PQ   GP  + G+ G      +RG A        
Sbjct: 88  LGPGPMGLMGPRG----PPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGE 143

Query: 130 --------PPGAMGILRARGGRGTGSQSPLPASLGVPPPPAM-GVQRARGGRGVGSESPP 180
                    PG  G++  +G RG      LP   G+     + G++   G  GV  E P 
Sbjct: 144 DGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGE-PG 202

Query: 181 RWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPR 240
             G     + G   Q G RG L      V +P PA G   + G  G       +G A P 
Sbjct: 203 APG-----ENGTPGQTGARG-LPGERGRVGAPGPA-GARGSDGSVGPVGPAGPIGSAGP- 254

Query: 241 CDGDPKSRGGRG 252
             G P + G +G
Sbjct: 255 -PGFPGAPGPKG 265



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 42/152 (27%), Positives = 53/152 (34%), Gaps = 12/152 (7%)

Query: 16   ASPPGIGGPKSQWGKSG-WFSIAASWRVPPPPAMGVLKARGGRAW-GGRGAGSQSLPRGG 73
            A  PG  GP    GK G       S  V P  A+G     G +   G +G   +  PRG 
Sbjct: 960  AGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGL 1019

Query: 74   ASARCDGGPKSQGGKRGWLSVPSLPR--GGASPQCDGGPKSQGGKSGWLSVPASRGVAPP 131
               +   G +   G  G       P   G A P+   GP    GK G            P
Sbjct: 1020 PGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDG--------RTGHP 1071

Query: 132  GAMGILRARGGRGTGSQSPLPASLGVPPPPAM 163
            G +G    RG +G    +  P   G P PP +
Sbjct: 1072 GTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGV 1103


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 72/256 (28%), Positives = 94/256 (36%), Gaps = 42/256 (16%)

Query: 19  PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGG-RG----------AGSQ 67
           PG+ GP+ + G  G  +     R  PP ++G+    G     G +G          AG+ 
Sbjct: 578 PGVQGPEGKLGPLG--APGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNA 635

Query: 68  SLPRGGASARCDG--------GPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGW 119
            +P    +   DG        GP    G+RG    P  P G        GP  +GGK G 
Sbjct: 636 GVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPG-PTGFQGLPGPPGPPGEGGKPGD 694

Query: 120 LSVPASRGVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGV-GSES 178
             VP       PGA+G L  RG RG   +   P   G+P     G +   GG G  G + 
Sbjct: 695 QGVPGD-----PGAVGPLGPRGERGNPGERGEPGITGLP-----GEKGMAGGHGPDGPKG 744

Query: 179 PPRWGCLPTCDGGPKSQG--GKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGG 236
            P     P   G P  QG  G+RG    P      P    G +  +G  G A +    G 
Sbjct: 745 SPGPSGTPGDTGPPGLQGMPGERGIAGTP-----GPKGDRGGIGEKGAEGTAGNDGARGL 799

Query: 237 ASPRCDGDPKSRGGRG 252
             P   G P   G  G
Sbjct: 800 PGPL--GPPGPAGPTG 813



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 61/213 (28%), Positives = 75/213 (35%), Gaps = 44/213 (20%)

Query: 16   ASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGAS 75
            A  PG  GP  + GK G   +        P + G +  RG     G G G +  P     
Sbjct: 923  AGAPGPAGPLGEPGKEGPPGLRGD-----PGSHGRVGDRGPAGPPG-GPGDKGDPGEDGQ 976

Query: 76   ARCDGGPKSQG-----------GKRGWLSVPSLPRGGASPQCDG-----------GPKSQ 113
               DG P   G           G+RG   +P LP    +P   G           GP   
Sbjct: 977  PGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGP 1036

Query: 114  GGKSGWLSVPASRGVA----PPGAMGILRARGGRGTGSQSPLPASLGVPPPPA-MGVQRA 168
             G +G +  P   G A     PG  G +  RG RG    + LP S G P  P  +G    
Sbjct: 1037 PGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGD 1096

Query: 169  RGGRG-VGSESPPRWGCLPTCDGGPKSQGGKRG 200
             G RG  GS  P           GP  + GKRG
Sbjct: 1097 AGQRGDPGSRGPI----------GPPGRAGKRG 1119



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 80/292 (27%), Positives = 97/292 (33%), Gaps = 69/292 (23%)

Query: 16  ASPPGIGGPKSQWGKSGWFSIAASWRVP----------------------PPPAMGVLKA 53
           A PPG  GP+   G  G         VP                      PP   G    
Sbjct: 446 AGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGP 505

Query: 54  RGGRAW-------GGRGA-------GSQSLPRGGASARCDGGPKSQGGKRGWLSVPSLPR 99
           RG           G RGA       GS  LP G   A+ + GP    G +G    P  P 
Sbjct: 506 RGDPGTVGPPGPVGERGAPGNRGFPGSDGLP-GPKGAQGERGPVGSSGPKGSQGDPGRPG 564

Query: 100 GGASPQC---DGGPKSQG--GKSGWLSVPASRG-VAPPGAMGILRARGGRGTGSQSPLPA 153
               P      G P  QG  GK G L  P   G   PPG++GI      RG       P 
Sbjct: 565 EPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGI------RGQ------PG 612

Query: 154 SLGVPPPPAMGVQRARGGRGVGSESPPRWGCLPTCDG--------GPKSQGGKRGWLSVP 205
           S+G+P P        + G    +  P + G  P  DG        GP    G+RG    P
Sbjct: 613 SMGLPGPKGSSGDPGKPGEAGNAGVPGQRGA-PGKDGEVGPSGPVGPPGLAGERGEQGPP 671

Query: 206 A----SWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCD-GDPKSRGGRG 252
                  +  P    G     G +GV   P  +G   PR + G+P  RG  G
Sbjct: 672 GPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPG 723



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 67/262 (25%), Positives = 92/262 (35%), Gaps = 40/262 (15%)

Query: 18  PPGIGGPKSQWGKSG------WFSIAASWRVPPPPAMGVLKARGGRAW--------GGRG 63
           PPG  G   + G++G      +     +   P  P +  LK   G           G  G
Sbjct: 259 PPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPG 318

Query: 64  AGSQSLPRGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQG-----GKSG 118
           +  ++ P G   A    GP+   G+RG L     P    +    G P   G     G SG
Sbjct: 319 SKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSG 378

Query: 119 WLSVPASRGVA-PPGAMGILRARGGRG-TGSQSP-----LPASLGVPPPPAMGVQRARGG 171
           +   P  +G A P GA G    +G RG TG   P     LP ++G    P      A+G 
Sbjct: 379 FPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPG-----AKGP 433

Query: 172 RGVGSESPPRWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSP 231
            G    S P     P    GP+   G +G    P        P +   +   G      P
Sbjct: 434 TGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGD------PGVPGFKGEAGPKGEPGP 487

Query: 232 Y-LMGGASPRCDGDPKSRGGRG 252
           + + G   P   G+   RG RG
Sbjct: 488 HGIQGPIGP--PGEEGKRGPRG 507



 Score = 47.8 bits (112), Expect = 9e-06
 Identities = 75/255 (29%), Positives = 92/255 (36%), Gaps = 48/255 (18%)

Query: 20  GIGGPKSQWGKSGWFSIAASWRVPPPPAM----GVLKARGGRA-WGGRG-------AGSQ 67
           G  G   + G  G   I  S   P  P M    G   ARG     G RG        GS 
Sbjct: 357 GAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSP 416

Query: 68  SLPRGGASARCDGGPKSQG--GKRGWLSVPSL--PRGGASPQCDGGPKSQGGKSGWLSVP 123
            LP    +   DG P ++G  G  G    P    P G   PQ   GP+   G+ G   VP
Sbjct: 417 GLP---GAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVP 473

Query: 124 ASRGVA----PPGAMGILRARGGRG-TGSQSPLPASLGVPPPPAMGVQRARGGRGV-GSE 177
             +G A     PG  GI    G  G  G + P      V PP  +G + A G RG  GS+
Sbjct: 474 GFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSD 533

Query: 178 SPPRWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGA 237
             P          GPK   G+RG           P  + G   ++G  G    P L G  
Sbjct: 534 GLP----------GPKGAQGERG-----------PVGSSGPKGSQGDPGRPGEPGLPGAR 572

Query: 238 SPRCDGDPKSRGGRG 252
                G+P  +G  G
Sbjct: 573 G--LTGNPGVQGPEG 585



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 75/248 (30%), Positives = 90/248 (36%), Gaps = 31/248 (12%)

Query: 13  ERG-ASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPR 71
           E+G A   G  GPK   G SG           PP   G+         G RG      P+
Sbjct: 730 EKGMAGGHGPDGPKGSPGPSG-----TPGDTGPPGLQGMP--------GERGIAGTPGPK 776

Query: 72  GGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAPP 131
           G      + G +   G  G   +P  P G   P    G K + G  G +  P SRG   P
Sbjct: 777 GDRGGIGEKGAEGTAGNDGARGLPG-PLGPPGPAGPTGEKGEPGPRGLVGPPGSRG--NP 833

Query: 132 GAMGILRARGGRG-TGSQSP--LPASLGVPPPPAM-GVQRARGGRGV-GSESPPRWGCLP 186
           G+ G     G  G  G Q P   P   G P  P   G   + G +G+ GS  P     +P
Sbjct: 834 GSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVP 893

Query: 187 TCDGGPKSQG--GKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGD 244
              GG  +QG  G  G+    A  V  P PA     A G  G    P   G   P   GD
Sbjct: 894 GLKGGRGTQGPPGATGFPG-SAGRVGPPGPA----GAPGPAGPLGEPGKEG--PPGLRGD 946

Query: 245 PKSRGGRG 252
           P S G  G
Sbjct: 947 PGSHGRVG 954



 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 76/294 (25%), Positives = 100/294 (34%), Gaps = 79/294 (26%)

Query: 16  ASPPGIGGPKSQWGK------------SGWFSIAASWRVPPPP----------------- 46
           A PPG  GP+ + G              G   +      P PP                 
Sbjct: 134 AGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSA 193

Query: 47  --------------------AMGVLKARGGRAWGGRGAGSQSLPRGGASARCDGGPKSQG 86
                               ++G +  RG +   G+  G+   P G      D GP    
Sbjct: 194 QMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAG--PTGPPGEPGDPGPMGPI 251

Query: 87  GKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAPPGAMGILRARGGRG-T 145
           G RG    P  P     P  +G P    G+ G+   P +RG   PGA G+   +G RG  
Sbjct: 252 GSRGPEGPPGKPGEDGEPGRNGNP----GEVGFAGSPGARGF--PGAPGLPGLKGHRGHK 305

Query: 146 GSQSP-----LPASLG-VPPPPAMGVQRARGGRGVGSESPPRWGCLPTCDGGPKSQGGKR 199
           G + P      P S G   P   MG     G RG+    P   G L     GP+   G+R
Sbjct: 306 GLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGM----PGERGRL-----GPQGAPGQR 356

Query: 200 GWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKS-RGGRG 252
           G   +P      P P MG L   G  G   +P + G A P     P+  +G RG
Sbjct: 357 GAHGMPG----KPGP-MGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRG 405



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 56/205 (27%), Positives = 71/205 (34%), Gaps = 20/205 (9%)

Query: 13   ERGASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARG--GRAWGGRGAGSQSLP 70
            ERG   PG+ GP    GK G     A+    PP  +G   + G  G       AG+   P
Sbjct: 1003 ERGM--PGLPGPAGTPGKVG--PTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTP 1058

Query: 71   R--GGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDG--------GPKSQGGKSGWL 120
               G    R D G     G  G    P  P    +P   G        GP    G++G  
Sbjct: 1059 GRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKR 1118

Query: 121  SVPASRGVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGVGSESPP 180
             +P  +G  P G  G    RG RG           G+P PP  G    +G  G+     P
Sbjct: 1119 GLPGPQG--PRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPP--GPNGEQGSAGIPGPFGP 1174

Query: 181  RWGCLPTCDGGPKSQGGKRGWLSVP 205
            R    P    G +   G  G +  P
Sbjct: 1175 RGPPGPVGPSGKEGNPGPLGPIGPP 1199



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 58/214 (27%), Positives = 76/214 (35%), Gaps = 28/214 (13%)

Query: 60  GGRGAGSQSLPRGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGW 119
           G RG    + P G    R + GPK + G RG   +   P     P   G P       G 
Sbjct: 126 GIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPP-------GH 178

Query: 120 LSVPASRGVAPPGAMGILRARGGRGTGSQSPL-PASLG-VPPPPAMGVQRARGGRG---- 173
            S P   G++ P +  +       G GSQ  L P S+G V P    G+Q  +GG G    
Sbjct: 179 PSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGP 238

Query: 174 ------------VGSESPPRWGCLPTCDGGPKSQG--GKRGWLSVPASWVVSPTPAMGVL 219
                       +GS  P      P  DG P   G  G+ G+   P +      P +  L
Sbjct: 239 PGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGL 298

Query: 220 RARGGRGVALSPYLMGGASPRCDGDPKSRGGRGA 253
           +   G      P    GA P   G+    G  GA
Sbjct: 299 KGHRGHKGLEGPKGEVGA-PGSKGEAGPTGPMGA 331



 Score = 35.4 bits (80), Expect = 0.049
 Identities = 46/155 (29%), Positives = 51/155 (32%), Gaps = 25/155 (16%)

Query: 19   PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASA-- 76
            PG  GP    G +G      S     PP         GRA G RG      PRG      
Sbjct: 1085 PGTPGPVGAPGDAGQRGDPGSRGPIGPP---------GRA-GKRGLPGPQGPRGDKGDHG 1134

Query: 77   -RCDGGPKSQGGKRGWLSVPSLP--------RGGASPQCDGGPKSQGGKSGWLSVPASRG 127
             R D G K   G  G   +P  P         G   P    GP    G SG    P   G
Sbjct: 1135 DRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLG 1194

Query: 128  -VAPPGAMGILRARGGRGTGSQSPLPASLGVPPPP 161
             + PPG  G +   G  G   +   P   G P PP
Sbjct: 1195 PIGPPGVRGSVGEAGPEGPPGE---PGPPGPPGPP 1226


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 74/256 (28%), Positives = 92/256 (35%), Gaps = 53/256 (20%)

Query: 18   PPGIGGPKSQWGKSGWFSIAAS---WRVPPPP----------AMGVLKARGGRAWGGRGA 64
            PPG+ G K   G  G+  +        +P PP          +MG   A G R   G   
Sbjct: 1125 PPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGP-T 1183

Query: 65   GSQSLPR--GGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSV 122
            GS+  P   GG       G K + G  G    P  P G   P+ D G K   G SG    
Sbjct: 1184 GSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAP-GIPGPKGDIGEKGDSGPSGAAGP 1242

Query: 123  PASRGVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAM-GVQRARGGRG----VGSE 177
            P  +G  PPG        G +G+   + LP  LG P  P + G+  + G +G    VG  
Sbjct: 1243 PGKKG--PPGE------DGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGP 1294

Query: 178  SPPRWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGA 237
             PP     P   G P    GKRG           P+  MG     G +G           
Sbjct: 1295 GPPGASGEPGAPGPP----GKRG-----------PSGHMGREGREGEKGAK--------G 1331

Query: 238  SPRCDGDPKSRGGRGA 253
             P  DG P   G  GA
Sbjct: 1332 EPGPDGPPGRTGPMGA 1347



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 68/237 (28%), Positives = 87/237 (36%), Gaps = 39/237 (16%)

Query: 16  ASPPGIGGPKSQWGKSGWFSIAASWRVPP----PPAMGVLKARGGR----AWGGRGAGSQ 67
           A PPG  GP+   G SG   +            P   G +  +G +    A G RG    
Sbjct: 703 AGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGP 762

Query: 68  SLPRGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDG--------GPKSQGGKSGW 119
             P+G A    + GP    G++G L VP LP     P   G        GP  + GKSG 
Sbjct: 763 EGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGK 822

Query: 120 LSVPASRGV-APPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGV-GSE 177
              P   G   PPG+ G    RG  G   Q      +G    P +      G +G+ G +
Sbjct: 823 TGQPGLEGERGPPGSRG---ERGQPGATGQPGPKGDVGQDGAPGI-----PGEKGLPGLQ 874

Query: 178 SPPRWGCLPTCDGGPKSQG--------GKRGWLSVPASWVVSPTPAMGVLRARGGRG 226
            PP +   P   G P  QG        G+RG L         P    GVL  +G  G
Sbjct: 875 GPPGF---PGPKGPPGHQGKDGRPGHPGQRGELGFQGQ--TGPPGPAGVLGPQGKTG 926



 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 64/218 (29%), Positives = 77/218 (35%), Gaps = 25/218 (11%)

Query: 13   ERGASPPGIGGPKSQWGKSGWFSI-AASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPR 71
            ERG  PPG  GP  + G  G      A   + PP  +G     G R + G        P+
Sbjct: 933  ERG--PPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPG--------PK 982

Query: 72   GGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRG-VAP 130
            GG     D GP    G +G    P  P G      + GP    G  G      S G V P
Sbjct: 983  GGPG---DPGPTGLKGDKG----PPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGP 1035

Query: 131  PGAMGILRARGGRGTGSQSPLPASLG-VPPPPAMGVQRARGGRGVGSESPPRWGCLPTCD 189
             G  G    RG  G   +  +P  LG + PP A G     G +G       +       D
Sbjct: 1036 AGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGD 1095

Query: 190  GGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGV 227
             GP  Q G RG    P      P  A G    RG  G+
Sbjct: 1096 AGPPGQPGIRGPAGHP-----GPPGADGAQGRRGPPGL 1128



 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 77/279 (27%), Positives = 96/279 (34%), Gaps = 59/279 (21%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGA--GSQSLP--RGG 73
            P G  G K   G+ G         +P P  +G L   G     G     G    P  +G 
Sbjct: 1032 PVGPAGKKGSRGERGPPGPTGKDGIPGP--LGPLGPPGAAGPSGEEGDKGDVGAPGHKGS 1089

Query: 74   ASARCDGGPKSQGGKRGWLSVPSLP-----RGGASPQCDGGPKSQGGKSGWLSV---PAS 125
               + D GP  Q G RG    P  P     +G   P    G K   G  G++ V   P  
Sbjct: 1090 KGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGL 1149

Query: 126  RGVAPP----------GAMGILRARGGRG----TGSQSP--LPASLGVP----------- 158
            +G+  P          G+MG   A G RG    TGS+    LP  +G P           
Sbjct: 1150 QGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGD 1209

Query: 159  -----PPPAMGVQRARGGRGVGSESPPRWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPT 213
                 PP A G+   +G  G   +S P     P    GP  + G +G         V PT
Sbjct: 1210 AGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKG--------SVGPT 1261

Query: 214  PAMGVLRARGGRGVALSPYLMGGASPRCDGDPKSRGGRG 252
               G L   G  GV+         SP   GDP   GG G
Sbjct: 1262 GLPGDLGPPGDPGVSGI-----DGSPGEKGDPGDVGGPG 1295



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 77/302 (25%), Positives = 95/302 (31%), Gaps = 83/302 (27%)

Query: 19  PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASARC 78
           PG+ G K Q G  G        +  PP   G   A G    G  G   +  PRG    R 
Sbjct: 556 PGLPGEKGQRGDFGHVG-----QPGPPGEDGERGAEGPP--GPTGQAGEPGPRGLLGPRG 608

Query: 79  DGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQG--------GKSGWLSVPASRGVAP 130
             GP  + G  G    P        P   G P  QG        G  G +  P  +G  P
Sbjct: 609 SPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKG--P 666

Query: 131 PGAMGILRARGGRG-------------TGSQSPLPASLGVPP-PPAMGVQRARGGRGV-- 174
           PG  GI    G  G              G+Q P P S G P  P   GV+   G RG+  
Sbjct: 667 PGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGP-PGSAGPPGYPGPRGVKGTSGNRGLQG 725

Query: 175 --------------------------------GSESP--PRWGCLPTCDGGPKSQGGKRG 200
                                           G + P  P+       + GP    G++G
Sbjct: 726 EKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKG 785

Query: 201 WLSVPA--SWVVSPTP--------AMGVLRARGGRGVALSPYLMGGASPRCDGDPKSRGG 250
            L VP    +   P P         +G +  +G  G    P L G   P     P SRG 
Sbjct: 786 KLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGP-----PGSRGE 840

Query: 251 RG 252
           RG
Sbjct: 841 RG 842



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 59/221 (26%), Positives = 79/221 (35%), Gaps = 30/221 (13%)

Query: 13   ERGA-SPPGIGGPKSQWGKSGWFSIAASWRVP----PPPAMGVLKARGGRAWGGRGAGSQ 67
            E GA  PPG  GP    G+ G      +   P    PP   G + ARG     G   G +
Sbjct: 1302 EPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVG-PEGLR 1360

Query: 68   SLPRGGASARCDGGPKSQG--GKRGWLSVPSLPRGGASPQCDG---------GPKSQGGK 116
             +P         G P   G  G  G   +P L +G   P+ +          GP  + G+
Sbjct: 1361 GIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGL-KGDTGPKGEKGHIGLIGLIGPPGEAGE 1419

Query: 117  SGWLSVPASRGVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAM-GVQRARGGRGVG 175
             G   +P  +G  PPG  G          G   P+  SLG P PP + G    +G +G  
Sbjct: 1420 KGDQGLPGVQG--PPGPKG--------DPGPPGPI-GSLGHPGPPGVAGPLGQKGSKGSP 1468

Query: 176  SESPPRWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAM 216
                PR    P    GP     +   L     +V  P P +
Sbjct: 1469 GSMGPRGDTGPAGPPGPPGAPAELHGLRRRRRFVPVPLPVV 1509


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein
           [Homo sapiens]
          Length = 1650

 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 68/241 (28%), Positives = 89/241 (36%), Gaps = 35/241 (14%)

Query: 19  PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASARC 78
           PG+ G K   G +G      +  +P PP     +   G   G RG   +S PRG    + 
Sbjct: 478 PGLPGEKGHRGDTG------AQGLPGPPGEDGERGDDGEI-GPRGLPGESGPRGLLGPKG 530

Query: 79  DGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAPPGAMGILR 138
             G     G RG +  P  P+G   PQ + GP  Q G  G   +P      P GA+G   
Sbjct: 531 PPGIPGPPGVRG-MDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP-----GPQGAIGPHG 584

Query: 139 ARGGRGTGSQSPLPASLGVP-------PPPAMGVQRARGGRGVGSESPPRWGCLPTCDG- 190
            +G +G      +P S G P       PP   G Q   G +G      PR   +   DG 
Sbjct: 585 EKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRG--VKGVDGI 642

Query: 191 -GPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKSRG 249
            G K   G++G    P           G +  +G RG    P   G   P     PK R 
Sbjct: 643 RGLKGHKGEKGEDGFPG--------FKGDIGVKGDRGEVGVPGSRGEDGPE---GPKGRT 691

Query: 250 G 250
           G
Sbjct: 692 G 692



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 76/253 (30%), Positives = 90/253 (35%), Gaps = 31/253 (12%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASAR 77
            PPG  GP  Q G +G     A          G   A+G    G RG      P G     
Sbjct: 1023 PPGPIGPVGQPGAAG-----ADGEPGARGPQGHFGAKGDE--GTRGFNGPPGPIGLQGLP 1075

Query: 78   CDGGPKSQGGKRGWLSVPSLP--RGGASPQCDGGPKSQGGKSGWLSVPASRG----VAPP 131
               G K + G  G +  P  P  RG A P    GP+   G  G L  P  +G       P
Sbjct: 1076 GPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSP 1135

Query: 132  GAM---GILRARGGRGTGSQSPLPASLGVPPPPA-MGVQRARGGRG-VGSESPPRWGCLP 186
            G     G+   RG RG   +S  P   G P P    G    +G  G VG    P     P
Sbjct: 1136 GIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPG----P 1191

Query: 187  TCDGGPKSQGGKR------GWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPR 240
              +GGP+ Q G +      G    P S    PT   G     G RG A SP   G    +
Sbjct: 1192 PGEGGPRGQDGAKGDRGEDGEPGQPGS--PGPTGENGPPGPLGKRGPAGSPGSEGRQGGK 1249

Query: 241  -CDGDPKSRGGRG 252
               GDP + G  G
Sbjct: 1250 GAKGDPGAIGAPG 1262



 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 65/250 (26%), Positives = 82/250 (32%), Gaps = 66/250 (26%)

Query: 7    VNFTVEERGASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGS 66
            V F  +     PPG+ GP+   G++G          P PP                  G 
Sbjct: 826  VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPP------------------GE 867

Query: 67   QSLP--RGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQG--GKSGWLSV 122
            Q LP   G    + D GP    GK G   +   P     P   GGP  +G  G SG    
Sbjct: 868  QGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSG---- 923

Query: 123  PASRGVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGVGSESPPRW 182
                   PPG  G    RG  G+G     P   G   PP      A G +GV  E  P  
Sbjct: 924  -------PPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPG-----AAGEKGVPGEKGPI- 970

Query: 183  GCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCD 242
                    GP  + G +G + +P      P    GV    G +G                
Sbjct: 971  --------GPTGRDGVQGPVGLP-----GPAGPPGVAGEDGDKGEV-------------- 1003

Query: 243  GDPKSRGGRG 252
            GDP  +G +G
Sbjct: 1004 GDPGQKGTKG 1013



 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 67/247 (27%), Positives = 91/247 (36%), Gaps = 24/247 (9%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASAR 77
            PPG  GP    G  G          P PP  G  + + G A G RG   +    G     
Sbjct: 1164 PPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDG-AKGDRGEDGEPGQPGSPGPT 1222

Query: 78   CDGGPKSQGGKRGWLSVPSLP--RGGASPQCDGGPKSQGGKSGWLSVPASRGVAPP---- 131
             + GP    GKRG    P     +GG   + D G     GK+G +      G   P    
Sbjct: 1223 GENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLR 1282

Query: 132  GAMGILRARGGRGTGSQSPLPASLGVPPPPAM-GVQRARGGRG----VGSESPPRWGCLP 186
            G  G +  +G  G   Q+  P  +G P  P + G   A+G +G    +G   PP      
Sbjct: 1283 GLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEK 1342

Query: 187  TCDG--GPKSQGGKRGWLSVP-ASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDG 243
               G  GP+   G++G + +P AS  + P    G+    G +G        G   P   G
Sbjct: 1343 GDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGA------KGATGP---G 1393

Query: 244  DPKSRGG 250
             PK   G
Sbjct: 1394 GPKGEKG 1400



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 78/312 (25%), Positives = 96/312 (30%), Gaps = 92/312 (29%)

Query: 20  GIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAW----GGRGAGSQSLPRGGAS 75
           G+ G K + G+ G+           P   G +  +G R      G RG      P+G   
Sbjct: 644 GLKGHKGEKGEDGF-----------PGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTG 692

Query: 76  ARCDGGPKSQGGKRGWLSVPSLP------------------------------------- 98
              D GP    G++G L VP LP                                     
Sbjct: 693 PTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG 752

Query: 99  -RGGASPQCDGGPKSQGGKSGWLSVPASRGV-APPGAMGILRARGGRG-TGSQSP--LPA 153
            RG   P+   GP+   GKSG        G   PPG  G+   +G  G  G + P   P 
Sbjct: 753 ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPG 812

Query: 154 SLGVP-------------------PPPAMGVQRARGGRGV----GSESPPRWGCLPTCDG 190
             G+P                   PP  +G Q A G  G     G   PP     P  + 
Sbjct: 813 KDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPG----PPGEQ 868

Query: 191 GPKSQGGKRGWLSVP----ASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCD---- 242
           G     GK G    P    A     P    G    RG  G A  P L G   P       
Sbjct: 869 GLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPA 928

Query: 243 GDPKSRGGRGAG 254
           G P  RG  G+G
Sbjct: 929 GSPGERGAAGSG 940



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 73/267 (27%), Positives = 91/267 (34%), Gaps = 38/267 (14%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAM-------GVLKARG--------GRAWGGR 62
            PPG GGP+ Q G  G          P  P         G L  RG        GR  GG+
Sbjct: 1191 PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQ-GGK 1249

Query: 63   GAGSQSLPRGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSV 122
            GA       G        GP    GK G   +  LP G    Q   G   Q G  G +  
Sbjct: 1250 GAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLP-GSVGQQGRPGATGQAGPPGPVGP 1308

Query: 123  PASRGV----------APPGAMGILRARGGRGTGSQSPLPASLGVPPPPA-MGVQRARGG 171
            P   G+            PG +G++   G +G      LP   G P     MG+  A G 
Sbjct: 1309 PGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGP 1368

Query: 172  RGVGSE------SPPRWGCLPTCDGGPKSQGGKRG--WLSVPASWVVSPTPAMGVLRARG 223
             G G        + P+     T  GGPK + G +G      P   V+ P P     + R 
Sbjct: 1369 IGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTR- 1427

Query: 224  GRGVALSPYLMGGASPRCDGDPKSRGG 250
             R V  S  +    +    G P S GG
Sbjct: 1428 -RSVDGSRLMQEDEAIPTGGAPGSPGG 1453



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 76/286 (26%), Positives = 100/286 (34%), Gaps = 59/286 (20%)

Query: 19  PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGV-LKARGGRAWGGRG-------AGSQS-L 69
           PG  G   + G  G   +  S   P PP   + L  R G   G +G       A +Q+ L
Sbjct: 333 PGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAIL 392

Query: 70  PRGGASARCDGGPKSQGGKRGWLSVPSLP-----------RGGASPQCDGGPKSQGGKSG 118
            +   + R   GP    G+ G L  P  P           +G   PQ   GP  + G+ G
Sbjct: 393 QQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRG 452

Query: 119 WLSVPASRGVAPPGAMGILRARGGRGTGSQSPLP---------ASLGVPPPPAMGVQRAR 169
                 +RG+  PG  G+   +G RG      LP          + G+P PP    +R  
Sbjct: 453 RAGADGARGM--PGDPGV---KGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGD 507

Query: 170 GG----RGVGSESPPRWGCLPT-------------CDG--GPKSQGGKRGWLSVPASWVV 210
            G    RG+  ES PR    P               DG  GPK   G +G    P     
Sbjct: 508 DGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT 567

Query: 211 SPTPAM----GVLRARGGRGVALSPYLMGGASPRCDGDPKSRGGRG 252
             T  +    G +   G +G    P L G   P  DG P   G  G
Sbjct: 568 PGTQGLPGPQGAIGPHGEKGPQGKPGLPG--MPGSDGPPGHPGKEG 611



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 12/100 (12%)

Query: 81  GPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAPPGAMGILRAR 140
           GP+   G++G    P++   G   +   GP    G +G +  P  +G   PG +G     
Sbjct: 291 GPRGLKGEKG---EPAVLEPGMLVE---GPPGPEGPAGLIGPPGIQG--NPGPVG---DP 339

Query: 141 GGRGTGSQSPLPASLGVPPPPAMGVQRA-RGGRGVGSESP 179
           G RG   ++ LP S G P PP   +    R G G G + P
Sbjct: 340 GERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGP 379



 Score = 33.5 bits (75), Expect = 0.18
 Identities = 38/121 (31%), Positives = 46/121 (38%), Gaps = 12/121 (9%)

Query: 16   ASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAW-GGRGA-GSQSLP--R 71
            A PPG  GP    G  G     A      P  +G++   G +   G RG  G Q  P  +
Sbjct: 1300 AGPPGPVGPPGLPGLRG--DAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQK 1357

Query: 72   GGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAPP 131
            G        GP   GG  G L  P+ P+G       GGPK + G  G    P      PP
Sbjct: 1358 GEMGIPGASGPIGPGGPPG-LPGPAGPKGAKGATGPGGPKGEKGVQGPPGHP-----GPP 1411

Query: 132  G 132
            G
Sbjct: 1412 G 1412


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein
           [Homo sapiens]
          Length = 1629

 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 68/241 (28%), Positives = 89/241 (36%), Gaps = 35/241 (14%)

Query: 19  PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASARC 78
           PG+ G K   G +G      +  +P PP     +   G   G RG   +S PRG    + 
Sbjct: 457 PGLPGEKGHRGDTG------AQGLPGPPGEDGERGDDGEI-GPRGLPGESGPRGLLGPKG 509

Query: 79  DGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAPPGAMGILR 138
             G     G RG +  P  P+G   PQ + GP  Q G  G   +P      P GA+G   
Sbjct: 510 PPGIPGPPGVRG-MDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP-----GPQGAIGPHG 563

Query: 139 ARGGRGTGSQSPLPASLGVP-------PPPAMGVQRARGGRGVGSESPPRWGCLPTCDG- 190
            +G +G      +P S G P       PP   G Q   G +G      PR   +   DG 
Sbjct: 564 EKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRG--VKGVDGI 621

Query: 191 -GPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKSRG 249
            G K   G++G    P           G +  +G RG    P   G   P     PK R 
Sbjct: 622 RGLKGHKGEKGEDGFPG--------FKGDIGVKGDRGEVGVPGSRGEDGPE---GPKGRT 670

Query: 250 G 250
           G
Sbjct: 671 G 671



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 76/253 (30%), Positives = 90/253 (35%), Gaps = 31/253 (12%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASAR 77
            PPG  GP  Q G +G     A          G   A+G    G RG      P G     
Sbjct: 1002 PPGPIGPVGQPGAAG-----ADGEPGARGPQGHFGAKGDE--GTRGFNGPPGPIGLQGLP 1054

Query: 78   CDGGPKSQGGKRGWLSVPSLP--RGGASPQCDGGPKSQGGKSGWLSVPASRG----VAPP 131
               G K + G  G +  P  P  RG A P    GP+   G  G L  P  +G       P
Sbjct: 1055 GPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSP 1114

Query: 132  GAM---GILRARGGRGTGSQSPLPASLGVPPPPA-MGVQRARGGRG-VGSESPPRWGCLP 186
            G     G+   RG RG   +S  P   G P P    G    +G  G VG    P     P
Sbjct: 1115 GIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPG----P 1170

Query: 187  TCDGGPKSQGGKR------GWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPR 240
              +GGP+ Q G +      G    P S    PT   G     G RG A SP   G    +
Sbjct: 1171 PGEGGPRGQDGAKGDRGEDGEPGQPGS--PGPTGENGPPGPLGKRGPAGSPGSEGRQGGK 1228

Query: 241  -CDGDPKSRGGRG 252
               GDP + G  G
Sbjct: 1229 GAKGDPGAIGAPG 1241



 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 65/250 (26%), Positives = 82/250 (32%), Gaps = 66/250 (26%)

Query: 7   VNFTVEERGASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGS 66
           V F  +     PPG+ GP+   G++G          P PP                  G 
Sbjct: 805 VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPP------------------GE 846

Query: 67  QSLP--RGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQG--GKSGWLSV 122
           Q LP   G    + D GP    GK G   +   P     P   GGP  +G  G SG    
Sbjct: 847 QGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSG---- 902

Query: 123 PASRGVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGVGSESPPRW 182
                  PPG  G    RG  G+G     P   G   PP      A G +GV  E  P  
Sbjct: 903 -------PPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPG-----AAGEKGVPGEKGPI- 949

Query: 183 GCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCD 242
                   GP  + G +G + +P      P    GV    G +G                
Sbjct: 950 --------GPTGRDGVQGPVGLP-----GPAGPPGVAGEDGDKGEV-------------- 982

Query: 243 GDPKSRGGRG 252
           GDP  +G +G
Sbjct: 983 GDPGQKGTKG 992



 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 67/247 (27%), Positives = 91/247 (36%), Gaps = 24/247 (9%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASAR 77
            PPG  GP    G  G          P PP  G  + + G A G RG   +    G     
Sbjct: 1143 PPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDG-AKGDRGEDGEPGQPGSPGPT 1201

Query: 78   CDGGPKSQGGKRGWLSVPSLP--RGGASPQCDGGPKSQGGKSGWLSVPASRGVAPP---- 131
             + GP    GKRG    P     +GG   + D G     GK+G +      G   P    
Sbjct: 1202 GENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLR 1261

Query: 132  GAMGILRARGGRGTGSQSPLPASLGVPPPPAM-GVQRARGGRG----VGSESPPRWGCLP 186
            G  G +  +G  G   Q+  P  +G P  P + G   A+G +G    +G   PP      
Sbjct: 1262 GLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEK 1321

Query: 187  TCDG--GPKSQGGKRGWLSVP-ASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDG 243
               G  GP+   G++G + +P AS  + P    G+    G +G        G   P   G
Sbjct: 1322 GDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGA------KGATGP---G 1372

Query: 244  DPKSRGG 250
             PK   G
Sbjct: 1373 GPKGEKG 1379



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 78/312 (25%), Positives = 96/312 (30%), Gaps = 92/312 (29%)

Query: 20  GIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAW----GGRGAGSQSLPRGGAS 75
           G+ G K + G+ G+           P   G +  +G R      G RG      P+G   
Sbjct: 623 GLKGHKGEKGEDGF-----------PGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTG 671

Query: 76  ARCDGGPKSQGGKRGWLSVPSLP------------------------------------- 98
              D GP    G++G L VP LP                                     
Sbjct: 672 PTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG 731

Query: 99  -RGGASPQCDGGPKSQGGKSGWLSVPASRGV-APPGAMGILRARGGRG-TGSQSP--LPA 153
            RG   P+   GP+   GKSG        G   PPG  G+   +G  G  G + P   P 
Sbjct: 732 ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPG 791

Query: 154 SLGVP-------------------PPPAMGVQRARGGRGV----GSESPPRWGCLPTCDG 190
             G+P                   PP  +G Q A G  G     G   PP     P  + 
Sbjct: 792 KDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPG----PPGEQ 847

Query: 191 GPKSQGGKRGWLSVP----ASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCD---- 242
           G     GK G    P    A     P    G    RG  G A  P L G   P       
Sbjct: 848 GLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPA 907

Query: 243 GDPKSRGGRGAG 254
           G P  RG  G+G
Sbjct: 908 GSPGERGAAGSG 919



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 73/267 (27%), Positives = 91/267 (34%), Gaps = 38/267 (14%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAM-------GVLKARG--------GRAWGGR 62
            PPG GGP+ Q G  G          P  P         G L  RG        GR  GG+
Sbjct: 1170 PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQ-GGK 1228

Query: 63   GAGSQSLPRGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSV 122
            GA       G        GP    GK G   +  LP G    Q   G   Q G  G +  
Sbjct: 1229 GAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLP-GSVGQQGRPGATGQAGPPGPVGP 1287

Query: 123  PASRGV----------APPGAMGILRARGGRGTGSQSPLPASLGVPPPPA-MGVQRARGG 171
            P   G+            PG +G++   G +G      LP   G P     MG+  A G 
Sbjct: 1288 PGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGP 1347

Query: 172  RGVGSE------SPPRWGCLPTCDGGPKSQGGKRG--WLSVPASWVVSPTPAMGVLRARG 223
             G G        + P+     T  GGPK + G +G      P   V+ P P     + R 
Sbjct: 1348 IGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTR- 1406

Query: 224  GRGVALSPYLMGGASPRCDGDPKSRGG 250
             R V  S  +    +    G P S GG
Sbjct: 1407 -RSVDGSRLMQEDEAIPTGGAPGSPGG 1432



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 76/286 (26%), Positives = 100/286 (34%), Gaps = 59/286 (20%)

Query: 19  PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGV-LKARGGRAWGGRG-------AGSQS-L 69
           PG  G   + G  G   +  S   P PP   + L  R G   G +G       A +Q+ L
Sbjct: 312 PGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAIL 371

Query: 70  PRGGASARCDGGPKSQGGKRGWLSVPSLP-----------RGGASPQCDGGPKSQGGKSG 118
            +   + R   GP    G+ G L  P  P           +G   PQ   GP  + G+ G
Sbjct: 372 QQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRG 431

Query: 119 WLSVPASRGVAPPGAMGILRARGGRGTGSQSPLP---------ASLGVPPPPAMGVQRAR 169
                 +RG+  PG  G+   +G RG      LP          + G+P PP    +R  
Sbjct: 432 RAGADGARGM--PGDPGV---KGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGD 486

Query: 170 GG----RGVGSESPPRWGCLPT-------------CDG--GPKSQGGKRGWLSVPASWVV 210
            G    RG+  ES PR    P               DG  GPK   G +G    P     
Sbjct: 487 DGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT 546

Query: 211 SPTPAM----GVLRARGGRGVALSPYLMGGASPRCDGDPKSRGGRG 252
             T  +    G +   G +G    P L G   P  DG P   G  G
Sbjct: 547 PGTQGLPGPQGAIGPHGEKGPQGKPGLPG--MPGSDGPPGHPGKEG 590



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 12/100 (12%)

Query: 81  GPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAPPGAMGILRAR 140
           GP+   G++G    P++   G   +   GP    G +G +  P  +G   PG +G     
Sbjct: 270 GPRGLKGEKG---EPAVLEPGMLVE---GPPGPEGPAGLIGPPGIQG--NPGPVG---DP 318

Query: 141 GGRGTGSQSPLPASLGVPPPPAMGVQRA-RGGRGVGSESP 179
           G RG   ++ LP S G P PP   +    R G G G + P
Sbjct: 319 GERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGP 358



 Score = 33.5 bits (75), Expect = 0.18
 Identities = 38/121 (31%), Positives = 46/121 (38%), Gaps = 12/121 (9%)

Query: 16   ASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAW-GGRGA-GSQSLP--R 71
            A PPG  GP    G  G     A      P  +G++   G +   G RG  G Q  P  +
Sbjct: 1279 AGPPGPVGPPGLPGLRG--DAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQK 1336

Query: 72   GGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAPP 131
            G        GP   GG  G L  P+ P+G       GGPK + G  G    P      PP
Sbjct: 1337 GEMGIPGASGPIGPGGPPG-LPGPAGPKGAKGATGPGGPKGEKGVQGPPGHP-----GPP 1390

Query: 132  G 132
            G
Sbjct: 1391 G 1391


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein
           [Homo sapiens]
          Length = 1736

 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 68/241 (28%), Positives = 89/241 (36%), Gaps = 35/241 (14%)

Query: 19  PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASARC 78
           PG+ G K   G +G      +  +P PP     +   G   G RG   +S PRG    + 
Sbjct: 564 PGLPGEKGHRGDTG------AQGLPGPPGEDGERGDDGEI-GPRGLPGESGPRGLLGPKG 616

Query: 79  DGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAPPGAMGILR 138
             G     G RG +  P  P+G   PQ + GP  Q G  G   +P      P GA+G   
Sbjct: 617 PPGIPGPPGVRG-MDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP-----GPQGAIGPHG 670

Query: 139 ARGGRGTGSQSPLPASLGVP-------PPPAMGVQRARGGRGVGSESPPRWGCLPTCDG- 190
            +G +G      +P S G P       PP   G Q   G +G      PR   +   DG 
Sbjct: 671 EKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRG--VKGVDGI 728

Query: 191 -GPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKSRG 249
            G K   G++G    P           G +  +G RG    P   G   P     PK R 
Sbjct: 729 RGLKGHKGEKGEDGFPG--------FKGDIGVKGDRGEVGVPGSRGEDGPE---GPKGRT 777

Query: 250 G 250
           G
Sbjct: 778 G 778



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 76/253 (30%), Positives = 90/253 (35%), Gaps = 31/253 (12%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASAR 77
            PPG  GP  Q G +G     A          G   A+G    G RG      P G     
Sbjct: 1109 PPGPIGPVGQPGAAG-----ADGEPGARGPQGHFGAKGDE--GTRGFNGPPGPIGLQGLP 1161

Query: 78   CDGGPKSQGGKRGWLSVPSLP--RGGASPQCDGGPKSQGGKSGWLSVPASRG----VAPP 131
               G K + G  G +  P  P  RG A P    GP+   G  G L  P  +G       P
Sbjct: 1162 GPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSP 1221

Query: 132  GAM---GILRARGGRGTGSQSPLPASLGVPPPPA-MGVQRARGGRG-VGSESPPRWGCLP 186
            G     G+   RG RG   +S  P   G P P    G    +G  G VG    P     P
Sbjct: 1222 GIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPG----P 1277

Query: 187  TCDGGPKSQGGKR------GWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPR 240
              +GGP+ Q G +      G    P S    PT   G     G RG A SP   G    +
Sbjct: 1278 PGEGGPRGQDGAKGDRGEDGEPGQPGS--PGPTGENGPPGPLGKRGPAGSPGSEGRQGGK 1335

Query: 241  -CDGDPKSRGGRG 252
               GDP + G  G
Sbjct: 1336 GAKGDPGAIGAPG 1348



 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 65/250 (26%), Positives = 82/250 (32%), Gaps = 66/250 (26%)

Query: 7    VNFTVEERGASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGS 66
            V F  +     PPG+ GP+   G++G          P PP                  G 
Sbjct: 912  VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPP------------------GE 953

Query: 67   QSLP--RGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQG--GKSGWLSV 122
            Q LP   G    + D GP    GK G   +   P     P   GGP  +G  G SG    
Sbjct: 954  QGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSG---- 1009

Query: 123  PASRGVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGVGSESPPRW 182
                   PPG  G    RG  G+G     P   G   PP      A G +GV  E  P  
Sbjct: 1010 -------PPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPG-----AAGEKGVPGEKGPI- 1056

Query: 183  GCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCD 242
                    GP  + G +G + +P      P    GV    G +G                
Sbjct: 1057 --------GPTGRDGVQGPVGLP-----GPAGPPGVAGEDGDKGEV-------------- 1089

Query: 243  GDPKSRGGRG 252
            GDP  +G +G
Sbjct: 1090 GDPGQKGTKG 1099



 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 67/247 (27%), Positives = 91/247 (36%), Gaps = 24/247 (9%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASAR 77
            PPG  GP    G  G          P PP  G  + + G A G RG   +    G     
Sbjct: 1250 PPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDG-AKGDRGEDGEPGQPGSPGPT 1308

Query: 78   CDGGPKSQGGKRGWLSVPSLP--RGGASPQCDGGPKSQGGKSGWLSVPASRGVAPP---- 131
             + GP    GKRG    P     +GG   + D G     GK+G +      G   P    
Sbjct: 1309 GENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLR 1368

Query: 132  GAMGILRARGGRGTGSQSPLPASLGVPPPPAM-GVQRARGGRG----VGSESPPRWGCLP 186
            G  G +  +G  G   Q+  P  +G P  P + G   A+G +G    +G   PP      
Sbjct: 1369 GLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEK 1428

Query: 187  TCDG--GPKSQGGKRGWLSVP-ASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDG 243
               G  GP+   G++G + +P AS  + P    G+    G +G        G   P   G
Sbjct: 1429 GDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGA------KGATGP---G 1479

Query: 244  DPKSRGG 250
             PK   G
Sbjct: 1480 GPKGEKG 1486



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 78/312 (25%), Positives = 96/312 (30%), Gaps = 92/312 (29%)

Query: 20   GIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAW----GGRGAGSQSLPRGGAS 75
            G+ G K + G+ G+           P   G +  +G R      G RG      P+G   
Sbjct: 730  GLKGHKGEKGEDGF-----------PGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTG 778

Query: 76   ARCDGGPKSQGGKRGWLSVPSLP------------------------------------- 98
               D GP    G++G L VP LP                                     
Sbjct: 779  PTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG 838

Query: 99   -RGGASPQCDGGPKSQGGKSGWLSVPASRGV-APPGAMGILRARGGRG-TGSQSP--LPA 153
             RG   P+   GP+   GKSG        G   PPG  G+   +G  G  G + P   P 
Sbjct: 839  ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPG 898

Query: 154  SLGVP-------------------PPPAMGVQRARGGRGV----GSESPPRWGCLPTCDG 190
              G+P                   PP  +G Q A G  G     G   PP     P  + 
Sbjct: 899  KDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPG----PPGEQ 954

Query: 191  GPKSQGGKRGWLSVP----ASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCD---- 242
            G     GK G    P    A     P    G    RG  G A  P L G   P       
Sbjct: 955  GLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPA 1014

Query: 243  GDPKSRGGRGAG 254
            G P  RG  G+G
Sbjct: 1015 GSPGERGAAGSG 1026



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 73/267 (27%), Positives = 91/267 (34%), Gaps = 38/267 (14%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAM-------GVLKARG--------GRAWGGR 62
            PPG GGP+ Q G  G          P  P         G L  RG        GR  GG+
Sbjct: 1277 PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQ-GGK 1335

Query: 63   GAGSQSLPRGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSV 122
            GA       G        GP    GK G   +  LP G    Q   G   Q G  G +  
Sbjct: 1336 GAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLP-GSVGQQGRPGATGQAGPPGPVGP 1394

Query: 123  PASRGV----------APPGAMGILRARGGRGTGSQSPLPASLGVPPPPA-MGVQRARGG 171
            P   G+            PG +G++   G +G      LP   G P     MG+  A G 
Sbjct: 1395 PGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGP 1454

Query: 172  RGVGSE------SPPRWGCLPTCDGGPKSQGGKRG--WLSVPASWVVSPTPAMGVLRARG 223
             G G        + P+     T  GGPK + G +G      P   V+ P P     + R 
Sbjct: 1455 IGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTR- 1513

Query: 224  GRGVALSPYLMGGASPRCDGDPKSRGG 250
             R V  S  +    +    G P S GG
Sbjct: 1514 -RSVDGSRLMQEDEAIPTGGAPGSPGG 1539



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 76/286 (26%), Positives = 100/286 (34%), Gaps = 59/286 (20%)

Query: 19  PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGV-LKARGGRAWGGRG-------AGSQS-L 69
           PG  G   + G  G   +  S   P PP   + L  R G   G +G       A +Q+ L
Sbjct: 419 PGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAIL 478

Query: 70  PRGGASARCDGGPKSQGGKRGWLSVPSLP-----------RGGASPQCDGGPKSQGGKSG 118
            +   + R   GP    G+ G L  P  P           +G   PQ   GP  + G+ G
Sbjct: 479 QQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRG 538

Query: 119 WLSVPASRGVAPPGAMGILRARGGRGTGSQSPLP---------ASLGVPPPPAMGVQRAR 169
                 +RG+  PG  G+   +G RG      LP          + G+P PP    +R  
Sbjct: 539 RAGADGARGM--PGDPGV---KGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGD 593

Query: 170 GG----RGVGSESPPRWGCLPT-------------CDG--GPKSQGGKRGWLSVPASWVV 210
            G    RG+  ES PR    P               DG  GPK   G +G    P     
Sbjct: 594 DGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT 653

Query: 211 SPTPAM----GVLRARGGRGVALSPYLMGGASPRCDGDPKSRGGRG 252
             T  +    G +   G +G    P L G   P  DG P   G  G
Sbjct: 654 PGTQGLPGPQGAIGPHGEKGPQGKPGLPG--MPGSDGPPGHPGKEG 697



 Score = 35.0 bits (79), Expect = 0.063
 Identities = 34/115 (29%), Positives = 49/115 (42%), Gaps = 15/115 (13%)

Query: 66  SQSLPRGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPAS 125
           S      GA+A    GP+   G++G    P++   G   +   GP    G +G +  P  
Sbjct: 365 SAETAHSGAAAH---GPRGLKGEKG---EPAVLEPGMLVE---GPPGPEGPAGLIGPPGI 415

Query: 126 RGVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRA-RGGRGVGSESP 179
           +G   PG +G     G RG   ++ LP S G P PP   +    R G G G + P
Sbjct: 416 QG--NPGPVG---DPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGP 465



 Score = 33.5 bits (75), Expect = 0.18
 Identities = 38/121 (31%), Positives = 46/121 (38%), Gaps = 12/121 (9%)

Query: 16   ASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAW-GGRGA-GSQSLP--R 71
            A PPG  GP    G  G     A      P  +G++   G +   G RG  G Q  P  +
Sbjct: 1386 AGPPGPVGPPGLPGLRG--DAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQK 1443

Query: 72   GGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAPP 131
            G        GP   GG  G L  P+ P+G       GGPK + G  G    P      PP
Sbjct: 1444 GEMGIPGASGPIGPGGPPG-LPGPAGPKGAKGATGPGGPKGEKGVQGPPGHP-----GPP 1497

Query: 132  G 132
            G
Sbjct: 1498 G 1498


>gi|154759255 collagen, type XXVIII precursor [Homo sapiens]
          Length = 1125

 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 69/245 (28%), Positives = 89/245 (36%), Gaps = 29/245 (11%)

Query: 18  PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASAR 77
           PPG  GPK   G  G       +  P  P +G    +G R   GR      +  G     
Sbjct: 329 PPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQP 388

Query: 78  CDGGPKSQGGKRGWLSVPSLP-RGGASPQCDGGPKSQGGKSG--WLSVPASRG----VAP 130
              GP+   G+RG      LP  G   P+ + G +   G  G   LS+   +G    V P
Sbjct: 389 GPRGPEGVPGERG------LPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGP 442

Query: 131 PGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRG-VGSESP--PRWGCLPT 187
            G MGI     G G+  +  +   +G P P     Q   G +G VG   P  PR G +  
Sbjct: 443 QGPMGI----PGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPR-GPVGI 497

Query: 188 CDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKS 247
              GPK + G  G    P           G   A G +G A  P   G   P   G P  
Sbjct: 498 GVQGPKGEPGSIGLPGQPG--------VPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGP 549

Query: 248 RGGRG 252
           +G  G
Sbjct: 550 KGDEG 554



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 64/197 (32%), Positives = 82/197 (41%), Gaps = 37/197 (18%)

Query: 19  PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGA-GSQSLPRGGASAR 77
           PG  GPK + G  G F +  +  +P PP       +G R  GG G  G +  P  G S R
Sbjct: 568 PGPEGPKGEPGIMGPFGMPGT-SIPGPPG-----PKGDR--GGPGIPGFKGEP--GLSIR 617

Query: 78  CDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAPPGAMGIL 137
              GPK   G RG +  P L +G   P   G P+   G  G + +   RGV   GA G  
Sbjct: 618 ---GPKGVQGPRGPVGAPGL-KGDGYPGVPG-PRGLPGPPGPMGL---RGVGDTGAKGEP 669

Query: 138 RARGG------RGTGSQSP--------LPASLGVPPPPAMGVQRARGGRGVGSESPPRWG 183
             RG       RG G+Q P        LP     P PP  G Q  +G +G      P+ G
Sbjct: 670 GVRGPPGPSGPRGVGTQGPKGDTGQKGLPGP---PGPPGYGSQGIKGEQGPQGFPGPK-G 725

Query: 184 CLPTCDGGPKSQGGKRG 200
            +     G K + G+RG
Sbjct: 726 TMGHGLPGQKGEHGERG 742



 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 70/254 (27%), Positives = 92/254 (36%), Gaps = 39/254 (15%)

Query: 13  ERGASPPGIGGPKSQWGKSG--------WFSI-AASWRVPPPPAMGVLKARGGRAWGGRG 63
           ERG    G  GPK + G  G          SI      + P    G +   G  + G +G
Sbjct: 399 ERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQG 458

Query: 64  AGSQSLPRGGASARCDGGPKSQG--GKRGWLSVPSLPRG--GASPQCDGGPKSQGGKSGW 119
                 P G       G P S+G  G+ G    P+ PRG  G   Q   GPK + G  G 
Sbjct: 459 IQGPIGPPGPQGPAGQGLPGSKGEVGQMG----PTGPRGPVGIGVQ---GPKGEPGSIGL 511

Query: 120 LSVPASRGVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRG-VGSES 178
                      PG  G+    G  G   ++ LP + G   PP  G    +G  G  GS+ 
Sbjct: 512 -----------PGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKG 560

Query: 179 PPRWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGAS 238
                 LP  + GPK + G  G   +P + +  P    G    RGG G+   P   G   
Sbjct: 561 NQGQRGLPGPE-GPKGEPGIMGPFGMPGTSIPGPPGPKG---DRGGPGI---PGFKGEPG 613

Query: 239 PRCDGDPKSRGGRG 252
               G    +G RG
Sbjct: 614 LSIRGPKGVQGPRG 627



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 68/251 (27%), Positives = 81/251 (32%), Gaps = 48/251 (19%)

Query: 18  PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASAR 77
           P GI G  SQ G+ G         + PP   G     G    G +G   Q  P G     
Sbjct: 445 PMGIPGIGSQ-GEQG-----IQGPIGPPGPQG---PAGQGLPGSKGEVGQMGPTGPRGPV 495

Query: 78  CDG--GPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASR------GVA 129
             G  GPK + G  G    P +P          G     GK G   +P +R      G  
Sbjct: 496 GIGVQGPKGEPGSIGLPGQPGVP----------GEDGAAGKKGEAGLPGARGPEGPPGKG 545

Query: 130 PPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGVGSESPPRWGCLPTCD 189
            PG  G    +G +G   Q  LP   G  P    G+    G  G     PP         
Sbjct: 546 QPGPKGDEGKKGSKGNQGQRGLPGPEG--PKGEPGIMGPFGMPGTSIPGPP--------- 594

Query: 190 GGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASP------RCDG 243
            GPK   G RG   +P           G    +G RG   +P L G   P         G
Sbjct: 595 -GPK---GDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPG 650

Query: 244 DPKSRGGRGAG 254
            P   G RG G
Sbjct: 651 PPGPMGLRGVG 661


>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
          Length = 684

 Score = 55.5 bits (132), Expect = 5e-08
 Identities = 59/187 (31%), Positives = 68/187 (36%), Gaps = 31/187 (16%)

Query: 18  PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASAR 77
           PPG  GP  + G+ G    A    +P PP     K   G+      AG   LP       
Sbjct: 33  PPGPPGPPGKPGQDGIDGEAGPPGLPGPPGP---KGAPGKPGKPGEAGLPGLPGVDGLTG 89

Query: 78  CDG--GPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVA-PPGAM 134
            DG  GPK   G+RG L  P             GP   GGK G    P   GV+ PPG +
Sbjct: 90  RDGPPGPKGAPGERGSLGPP-------------GPPGLGGK-GLPGPPGEAGVSGPPGGI 135

Query: 135 GILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGVGSESPPRWGCLPTCDGGPKS 194
           G+   RG  G      LP   G P PP        G  GV  E      C   C  GP  
Sbjct: 136 GL---RGPPGPSGLPGLPGPPGPPGPP--------GHPGVLPEGATDLQCPSICPPGPPG 184

Query: 195 QGGKRGW 201
             G  G+
Sbjct: 185 PPGMPGF 191



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 60/221 (27%), Positives = 82/221 (37%), Gaps = 46/221 (20%)

Query: 13  ERGASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRG 72
           ERG  P G  GPK   G+ G           P    GV    G     G+  G   +P G
Sbjct: 269 ERG--PEGFRGPKGDLGRPG-----------PKGTPGVAGPSGEPGMPGKD-GQNGVP-G 313

Query: 73  GASARCDGGPKSQGGKRGWLSVPSLP-----------RGGASPQCDGGPKSQGGKSGWLS 121
               + + G     G++G   +P LP           RG A    + GP  + G  G   
Sbjct: 314 LDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAG 373

Query: 122 VPASRGVA-------------PPGAMGILRARGGRGTGSQSPLPASLG----VPPPPAMG 164
           +P  RG A             PPGA G+   +G +G+     LP   G    V      G
Sbjct: 374 MPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGG 433

Query: 165 VQRARGGRGV-GSESPP--RWGCLPTCDGGPKSQGGKRGWL 202
               +G +G+ GS+  P  +    P+   GPK + G RG L
Sbjct: 434 AAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGEL 474



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 73/246 (29%), Positives = 93/246 (37%), Gaps = 26/246 (10%)

Query: 16  ASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGAS 75
           A PPG+ GP    G  G         +P  P +  L  R G   G +GA  +   RG   
Sbjct: 52  AGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPP-GPKGAPGE---RGSLG 107

Query: 76  ARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRG-VAPPGAM 134
                GP   GGK   L  P    G + P    G +   G SG   +P   G   PPG  
Sbjct: 108 ---PPGPPGLGGK--GLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHP 162

Query: 135 GILRARGGRGTGSQSPLPASLGVPPPPAM-GVQRARGGRG----VGSESPPRWGCLPTCD 189
           G+L       T  Q P     G P PP M G +   G +G    VG +        P   
Sbjct: 163 GVLPE---GATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPA 219

Query: 190 GGPKSQG--GKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKS 247
           G P S G  G RG   +P    + P    G +  RG  G+  +P   G A  R +  P+ 
Sbjct: 220 GLPGSVGLQGPRGLRGLPGP--LGPPGDRGPIGFRGPPGIPGAP---GKAGDRGERGPEG 274

Query: 248 -RGGRG 252
            RG +G
Sbjct: 275 FRGPKG 280



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 68/259 (26%), Positives = 83/259 (32%), Gaps = 49/259 (18%)

Query: 20  GIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASARCD 79
           G  GPK   G+ G      S   P PP +G     G    G  G    S P GG   R  
Sbjct: 92  GPPGPKGAPGERG------SLGPPGPPGLG-----GKGLPGPPGEAGVSGPPGGIGLRGP 140

Query: 80  GGPKSQGGKRGWLSVPS-------LPRGGASPQCDG----------------GPKSQGGK 116
            GP    G  G    P        LP G    QC                  GP    G+
Sbjct: 141 PGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGE 200

Query: 117 SGWLSVPASRG-VAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPA-MGVQRARGGRGV 174
            G +     +G   PPG  G+  + G +G      LP  LG P     +G +   G  G 
Sbjct: 201 QGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGA 260

Query: 175 GSESPPRWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLM 234
             ++  R    P    GPK   G+ G    P   V  P+   G+    G  GV       
Sbjct: 261 PGKAGDRGERGPEGFRGPKGDLGRPGPKGTPG--VAGPSGEPGMPGKDGQNGV------- 311

Query: 235 GGASPRCDGDPKSRGGRGA 253
               P  DG     G  GA
Sbjct: 312 ----PGLDGQKGEAGRNGA 326



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 44/149 (29%), Positives = 56/149 (37%), Gaps = 29/149 (19%)

Query: 81  GPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVA----PPGAMGI 136
           G   Q G  G    P LP G   P+   G   + G++G   +P   G+     PPG  G 
Sbjct: 41  GKPGQDGIDGEAGPPGLP-GPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKG- 98

Query: 137 LRARGGRGTGSQSPLPASLGVPPPPAMGVQRARG----------GRGVGSESPPRWGCLP 186
             A G RG         SLG P PP +G +   G            G+G   PP    LP
Sbjct: 99  --APGERG---------SLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLP 147

Query: 187 TCDG--GPKSQGGKRGWLSVPASWVVSPT 213
              G  GP    G  G L   A+ +  P+
Sbjct: 148 GLPGPPGPPGPPGHPGVLPEGATDLQCPS 176



 Score = 36.6 bits (83), Expect = 0.022
 Identities = 71/275 (25%), Positives = 89/275 (32%), Gaps = 53/275 (19%)

Query: 18  PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARG-GRAWGGRG----AGSQSLP-- 70
           PPG  G +   G+ G  S+       P    G +  RG G A G +G    AGS  LP  
Sbjct: 395 PPGAPGVRGFQGQKG--SMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGD 452

Query: 71  ------------RGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSG 118
                       +G + +R + GPK   G  G   V  +P          GP    G  G
Sbjct: 453 KGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVP----------GPPGPLGLQG 502

Query: 119 WLSVPASRGVAPPGAMG-------ILRARGGR--------GTGSQSPL-PASLGVP---- 158
              VP   G   PG  G       I    GG             + PL P S+G P    
Sbjct: 503 VPGVPGITG--KPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAG 560

Query: 159 PPPAMGVQRARGGRGVGSESPPRWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGV 218
           PP   G   + G  G       R       D GP+   G RG      + +  P    G 
Sbjct: 561 PPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGP 620

Query: 219 LRARGGRGVALSPYLMGGASPRCDGDPKSRGGRGA 253
              +G  G +          P   GDP   G  GA
Sbjct: 621 QGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGA 655


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 68/237 (28%), Positives = 82/237 (34%), Gaps = 25/237 (10%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASAR 77
            PPG  GPK    + G      S    PP   G        A G  G+     P+G     
Sbjct: 2086 PPGPPGPKVSVDEPG---PGLSGEQGPPGLKG--------AKGEPGSNGDQGPKGDRGVP 2134

Query: 78   CDGGPKSQGGKRGWLSVPSLP--RGGASPQCDGGPKSQGGKSGWLSVPASRGVAPPGAMG 135
               G + + G RG    P LP  RG A P+  G P  QG +     V       PPGA G
Sbjct: 2135 GIKGDRGEPGPRGQDGNPGLPGERGMAGPE--GKPGLQGPRGPPGPVGGHGDPGPPGAPG 2192

Query: 136  ILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGVGSESPPRWGCLPTCDGGPKSQ 195
            +    G +G       P   G   PP  G+    G  G+     P     P    G   Q
Sbjct: 2193 LAGPAGPQGPSGLKGEPGETG---PPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQ 2249

Query: 196  GGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKSRGGRG 252
             G+ G    P         A G    RG  GV  SP L G   P+  G+P   G  G
Sbjct: 2250 VGETGKPGAPGR-----DGASGKDGDRGSPGVPGSPGLPGPVGPK--GEPGPTGAPG 2299



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 75/269 (27%), Positives = 91/269 (33%), Gaps = 38/269 (14%)

Query: 19   PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAW------GGRGAGSQSLPRG 72
            PG+ GP    G+ G         V  P A G   A GG A       G +G      PRG
Sbjct: 2280 PGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRG 2339

Query: 73   GASARCDGGPKSQGGKRGWLSVPSLPRG-----GASPQCDGGPKSQGGKSGWLSVPASRG 127
                    G     G+ G    P  P+G     G       GP    G  G L +P   G
Sbjct: 2340 EKGEAGRAGEPGDPGEDGQKGAPG-PKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPG 2398

Query: 128  ----------VAPPGAMGILRARGGRGTG---SQSPLPASLGVP-------PPPAMGVQR 167
                        P G MG     G RG      +  +P  LG P       PP A G++ 
Sbjct: 2399 APGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKG 2458

Query: 168  ARGGRGVGSESPPRWGCLPTCDG--GPKSQGGKRGWLSVPAS-WVVSPTPAMGVLRARGG 224
             +G  GVG   P      P   G  G   Q G RG    P S         +G    +G 
Sbjct: 2459 DKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGD 2518

Query: 225  RGVALSPYLMGGASPR-CDGDPKSRGGRG 252
            +G   S  ++G   PR   GD   RG RG
Sbjct: 2519 KGD--SAVILGPPGPRGAKGDMGERGPRG 2545



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 68/248 (27%), Positives = 85/248 (34%), Gaps = 41/248 (16%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASAR 77
            PPG    K + G  G     A  R   P   G     G  A G +G+     PRG    R
Sbjct: 1288 PPGSATAKGERGFPG-----ADGRPGSPGRAGNPGTPG--APGLKGSPGLPGPRGDPGER 1340

Query: 78   CDGGPKSQGGKRGWL---SVPSLP--RGGASPQCDGGPKSQGGKSGWLSVPASRGVAPPG 132
               GPK + G  G +     P LP  +G   P    GP+   G  G    P   G A  G
Sbjct: 1341 GPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKG 1400

Query: 133  AMGILRARGGRGTGSQSPLPASLGVP-------PPPAMGVQRARGGRGVGSESPPRWGCL 185
              G    RG  G G     P   G+P       P   +G    +G +G   +  P    L
Sbjct: 1401 DKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPG---L 1457

Query: 186  PTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCD-GD 244
            P   G P  QG               P    G +  +G RG    P  +G A  + + G 
Sbjct: 1458 PGQPGSPGEQG---------------PRGPPGAIGPKGDRGF---PGPLGEAGEKGERGP 1499

Query: 245  PKSRGGRG 252
            P   G RG
Sbjct: 1500 PGPAGSRG 1507



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 73/249 (29%), Positives = 89/249 (35%), Gaps = 26/249 (10%)

Query: 18   PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGR-AWGGRGAGSQSLPRGGASA 76
            P G  GP  + G+ G     A      P + G    RG   A G +G      P G A  
Sbjct: 1434 PQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGE 1493

Query: 77   RCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGP------KSQGGKSGWLSVPASRGVAP 130
            + + GP    G RG   V   P G   P+   GP      K + G+ G  +V       P
Sbjct: 1494 KGERGPPGPAGSRGLPGVAGRP-GAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGP 1552

Query: 131  PGAMGILRARGGRG-TGSQSPL-PASLGVPPPPAMGVQRARGGRG----VGSESPPRWGC 184
             G  G +   G RG TG Q    P  L +P  P  G +   G RG     G   PP    
Sbjct: 1553 KGEKGDVGPAGPRGATGVQGERGPPGLVLPGDP--GPKGDPGDRGPIGLTGRAGPPG--- 1607

Query: 185  LPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPR-CDG 243
                D GP  + G  G    P    V P    G +  +G  G    P L G A  R   G
Sbjct: 1608 ----DSGPPGEKGDPGRPGPPGP--VGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRG 1661

Query: 244  DPKSRGGRG 252
             P  RG  G
Sbjct: 1662 APGVRGPVG 1670



 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 65/251 (25%), Positives = 87/251 (34%), Gaps = 29/251 (11%)

Query: 19   PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASARC 78
            PG  GPK   G+ G          P PP   V    G R  G  G   Q  PRG      
Sbjct: 1687 PGSSGPKGDRGEPG---------PPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPG 1737

Query: 79   DGGPKSQGGKRGWLSVPSLP-----RGGASPQCDGGPKSQGGKSGWLSVPASRG------ 127
              G   + G  G+   P        RG A  + D GP    G+SG    P + G      
Sbjct: 1738 LPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNG 1797

Query: 128  ----VAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAM-GVQRARGGRGVGSESPPRW 182
                   PG  G+   RG +G    S  P   G P      G+    G  G   E   + 
Sbjct: 1798 AAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKG 1857

Query: 183  GCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCD 242
                +   G + + G +G    P   ++ P    G+    G  G    P + GG  P+ D
Sbjct: 1858 EKGDSGASGREGRDGPKGERGAPG--ILGPQGPPGLPGPVGPPGQGF-PGVPGGTGPKGD 1914

Query: 243  -GDPKSRGGRG 252
             G+  S+G +G
Sbjct: 1915 RGETGSKGEQG 1925



 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 66/257 (25%), Positives = 92/257 (35%), Gaps = 42/257 (16%)

Query: 13   ERGASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARG--GRAW--GGRGAGSQS 68
            ERG   PGI G   + G+ G   +       PP + G    +G  G A   G +G  +  
Sbjct: 2473 ERGE--PGIRGEDGRPGQEGPRGLTG-----PPGSRGERGEKGDVGSAGLKGDKGDSAVI 2525

Query: 69   L----PRGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPA 124
            L    PRG      + GP+   G +G       PRG      D G K + G  G   +P 
Sbjct: 2526 LGPPGPRGAKGDMGERGPRGLDGDKG-------PRGDNGDPGDKGSKGEPGDKGSAGLPG 2578

Query: 125  SRG-VAPPGAMGILRARGGRGTGSQSPLPASLG-------VPPPPAMGVQRARGGRGVGS 176
             RG + P G  G     G  G+  +  +P   G       + P    G +  +G  G+  
Sbjct: 2579 LRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDG 2638

Query: 177  ESPPRWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAM-GVLRARGGRGVALSPYLMG 235
            E   +    P    G     G+ G   VP     S  P   G++  +G RG         
Sbjct: 2639 EKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQ---SGAPGKEGLIGPKGDRGF-------- 2687

Query: 236  GASPRCDGDPKSRGGRG 252
               P   GD   +G RG
Sbjct: 2688 DGQPGPKGDQGEKGERG 2704



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 68/252 (26%), Positives = 84/252 (33%), Gaps = 51/252 (20%)

Query: 16   ASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGAS 75
            A PPG  GP  + G  G        R  PP  +           G RG   +   +G   
Sbjct: 1603 AGPPGDSGPPGEKGDPG--------RPGPPGPV-----------GPRGRDGEVGEKGDEG 1643

Query: 76   ARCDGGPKSQGGKRGWLSVPSL--PRGGASPQCDGGPKSQGGKSGWLSVPASRG-VAPPG 132
               D G   + G+RG    P +  P G    Q D G   + G  G       RG   PPG
Sbjct: 1644 PPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPG 1703

Query: 133  AMGIL-------RARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGV-GSESPPRWGC 184
              G L       R +G  G   Q       G P     G+  A G RG+ G   PP    
Sbjct: 1704 PPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDP-----GLPGAPGERGIEGFRGPPG--- 1755

Query: 185  LPTCDGGPKSQGGKRGWLSVPA----SWVVSPTPAMGVLRARGGRGVALSPYLMGGASPR 240
             P  D G +   G++G    P     S +     A G     G  G A          P 
Sbjct: 1756 -PQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKA--------GDPG 1806

Query: 241  CDGDPKSRGGRG 252
             DG P  RG +G
Sbjct: 1807 RDGLPGLRGEQG 1818



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 61/222 (27%), Positives = 75/222 (33%), Gaps = 42/222 (18%)

Query: 8    NFTVEERGASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQ 67
            +FT + R   P  +  PK Q G+ G   +      P  P +           G  GA   
Sbjct: 1237 SFTTQPR-PEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLP----------GRTGAPGP 1285

Query: 68   SLPRGGASAR-------CDGGPKSQG--GKRGWLSVPSL--------PRGGASPQCDGGP 110
              P G A+A+        DG P S G  G  G    P L        PRG    +   GP
Sbjct: 1286 QGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGP 1345

Query: 111  KSQGGKSGWLSVPASRGVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARG 170
            K + G  G   V    G   PG  G     G  G       P   G P  P   ++  +G
Sbjct: 1346 KGEPGAPG--QVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKG 1403

Query: 171  GRGV-GSESPPRWGC------LPTCDGGPKSQG-----GKRG 200
             RG  G   P   G       LP   G P  QG     GK+G
Sbjct: 1404 DRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKG 1445



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 86/291 (29%), Positives = 103/291 (35%), Gaps = 76/291 (26%)

Query: 13   ERGASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRA-WGGRGA----GSQ 67
            ERGA  PGI GP+   G  G            PP  G     GG    G RG     G Q
Sbjct: 1876 ERGA--PGILGPQGPPGLPGPVG---------PPGQGFPGVPGGTGPKGDRGETGSKGEQ 1924

Query: 68   SLP-----RG--GASARCDGGPKSQGGKRG---------------WLSVPSLPRGGASPQ 105
             LP     RG  G+    D   ++ G K                 +L VP   RG   P+
Sbjct: 1925 GLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRG---PK 1981

Query: 106  CDGGPKSQGGKSGWLSVPASRGV-------APPGAMGI-LRARGGRGTGSQSPLPASLGV 157
             D G +   GK G +  P  RG+        P G  G+ L  RG  G    +  P   G+
Sbjct: 1982 GDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGI 2041

Query: 158  P--PPPAMGVQRA-----RGGRG-------VGSESPPRWGCLPTCDGGPKSQGGKRGWLS 203
            P  P  A GV  A     RG RG        G + PP    LP   G P   G       
Sbjct: 2042 PGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPG---LPGTPGPPGPPG------- 2091

Query: 204  VPASWVVSPTPAM-GVLRARGGRGVALSPYLMGGASPRCD-GDPKSRGGRG 252
             P   V  P P + G     G +G    P   G   P+ D G P  +G RG
Sbjct: 2092 -PKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRG 2141



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 66/237 (27%), Positives = 80/237 (33%), Gaps = 48/237 (20%)

Query: 23   GPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAW-GGRG-AGSQSLPRGGASARCDG 80
            GPK   G+ G           PP   G +   G R   G RG  G Q  P      R   
Sbjct: 1979 GPKGDSGEQG-----------PPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPP 2027

Query: 81   GPKSQGGKRGWLSVPSLP--RGGASPQCDGGPKSQGGKSGWLSVPASRGVAPPGAMGILR 138
            GP    G+ G   +P LP   GG       G + + G+ G                    
Sbjct: 2028 GPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKG-------------------- 2067

Query: 139  ARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGV-GSESPPRWGCLPTCDGGPKSQG- 196
             RG +G      LP + G P PP   V     G G+ G + PP    L    G P S G 
Sbjct: 2068 ERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPG---LKGAKGEPGSNGD 2124

Query: 197  -GKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKSRGGRG 252
             G +G   VP        P       RG  G    P   G A P  +G P  +G RG
Sbjct: 2125 QGPKGDRGVPGIKGDRGEPG-----PRGQDGNPGLPGERGMAGP--EGKPGLQGPRG 2174



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 35/130 (26%), Positives = 49/130 (37%), Gaps = 16/130 (12%)

Query: 19   PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGG----RGAGSQSLPRGGA 74
            PG+ G K + G+ G        +   P   G++  +G R + G    +G   +   RG  
Sbjct: 2652 PGLAGHKGEMGEPG-----VPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTP 2706

Query: 75   SARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAPPGAM 134
                  GP    G  G    P  P G   P+   GP+   G+ G    P  R V  PG  
Sbjct: 2707 GIGGFPGPSGNDGSAG----PPGPPGSVGPR---GPEGLQGQKGERGPPGERVVGAPGVP 2759

Query: 135  GILRARGGRG 144
            G    RG +G
Sbjct: 2760 GAPGERGEQG 2769



 Score = 32.0 bits (71), Expect = 0.54
 Identities = 44/203 (21%), Positives = 64/203 (31%), Gaps = 25/203 (12%)

Query: 16   ASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAW-----GGRGAGSQSLP 70
            + P G  G     G+ G   +     +P P     L  + G        G  G       
Sbjct: 1793 SGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGE 1852

Query: 71   RGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAP 130
             G    + D G   + G+ G       P+G        GP+   G  G +  P       
Sbjct: 1853 DGRKGEKGDSGASGREGRDG-------PKGERGAPGILGPQGPPGLPGPVGPPGQGFPGV 1905

Query: 131  PGAMGILRARGGRGTGSQSPLPASLGV--PPPPAMGVQRARGGRGVGS-----------E 177
            PG  G    RG  G+  +  LP   G+   P     V R     G+ +           E
Sbjct: 1906 PGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDE 1965

Query: 178  SPPRWGCLPTCDGGPKSQGGKRG 200
            S   +  +P    GPK   G++G
Sbjct: 1966 SSGSFLPVPERRRGPKGDSGEQG 1988


>gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]
          Length = 957

 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 68/257 (26%), Positives = 98/257 (38%), Gaps = 48/257 (18%)

Query: 12  EERGASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLP- 70
           E+  A  PG+ GP  + G+ G   +  S     P   G   + G     G   G   +P 
Sbjct: 555 EKGNAGFPGLPGPAGEPGRHGKDGLMGS-----PGFKGEAGSPGAPGQDGT-RGEPGIPG 608

Query: 71  ----RGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASR 126
               RG    + + GP  Q GK+G   +P L     SP   G P S+G K      P  +
Sbjct: 609 FPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSK----GEPGIQ 664

Query: 127 GVAPPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQRARGGRGVGSESPPRWGCLP 186
           G+  PGA G+    G  G+  +   P  +G+P     G+Q  +G +G   E         
Sbjct: 665 GM--PGASGLKGEPGATGSPGE---PGYMGLP-----GIQGKKGDKGNQGEK-------- 706

Query: 187 TCDGGPKSQGGKRGWLSVPASWVV----------SPTPAMGVLRARGGRGVALSPYLMGG 236
               G + Q G+ G   +P    +                GV  A G +G +    LMG 
Sbjct: 707 ----GIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGP 762

Query: 237 ASPRCD-GDPKSRGGRG 252
           A P+   GDP  +G  G
Sbjct: 763 AGPKGQPGDPGPQGPPG 779



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 53/210 (25%), Positives = 69/210 (32%), Gaps = 36/210 (17%)

Query: 19  PGIGGPKSQWGKSGWFSIAA----SWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGA 74
           PGI G K   G  G   I      + R   P   G+    G +  G RG   +   RG  
Sbjct: 691 PGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAK--GERGEKGEPGVRGAI 748

Query: 75  SARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKS---------------------- 112
            ++ + G     G  G    P  P     P  DG P                        
Sbjct: 749 GSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVL 808

Query: 113 -QGGK----SGWLSVPASRGV-APPGAMGILRARGGRGTGSQSPLPASLGVPPPPAMGVQ 166
            Q G+       LS   S G+  PPG +G    RG  G   +  +P  +GVP  P  GV+
Sbjct: 809 LQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRP--GVR 866

Query: 167 RARGGRGVGSESPPRWGCLPTCDGGPKSQG 196
             +G  G   E   +    P   G P   G
Sbjct: 867 GLKGLPGRNGEKGSQGFGYPGEQGPPGPPG 896


>gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [Homo
           sapiens]
          Length = 828

 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 72/244 (29%), Positives = 88/244 (36%), Gaps = 43/244 (17%)

Query: 19  PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASARC 78
           PG  GP  + G  G      +   P  P  GV  A+GG   G RG      P+G    R 
Sbjct: 378 PGRRGPPGEIGAKGSKGYQGNSGAPGSP--GVKGAKGGP--GPRG------PKGEPGRRG 427

Query: 79  DGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGV----APPGAM 134
           D G K   G  G    P   +G   P+   GP+   G+ G       RG+     P GA+
Sbjct: 428 DPGTKGSPGSDG----PKGEKGDPGPE---GPRGLAGEVGNKGAKGDRGLPGPRGPQGAL 480

Query: 135 GILRARGGRGT-GSQSPL-----PASLGVPPPPAMGVQRARGGRGVGSESPPRWGCLPTC 188
           G    +G RG  G   P      P   G P  P       RG  G   E  PR       
Sbjct: 481 GEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRG 540

Query: 189 DGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKSR 248
           D G K + G++G    PA     P P  G    RG RGV           P  +G+P   
Sbjct: 541 DFGLKGEPGRKGEKGEPA----DPGPP-GEPGPRGPRGV-----------PGPEGEPGPP 584

Query: 249 GGRG 252
           G  G
Sbjct: 585 GDPG 588


>gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Homo
           sapiens]
          Length = 918

 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 72/244 (29%), Positives = 88/244 (36%), Gaps = 43/244 (17%)

Query: 19  PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASARC 78
           PG  GP  + G  G      +   P  P  GV  A+GG   G RG      P+G    R 
Sbjct: 378 PGRRGPPGEIGAKGSKGYQGNSGAPGSP--GVKGAKGGP--GPRG------PKGEPGRRG 427

Query: 79  DGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGV----APPGAM 134
           D G K   G  G    P   +G   P+   GP+   G+ G       RG+     P GA+
Sbjct: 428 DPGTKGSPGSDG----PKGEKGDPGPE---GPRGLAGEVGNKGAKGDRGLPGPRGPQGAL 480

Query: 135 GILRARGGRGT-GSQSPL-----PASLGVPPPPAMGVQRARGGRGVGSESPPRWGCLPTC 188
           G    +G RG  G   P      P   G P  P       RG  G   E  PR       
Sbjct: 481 GEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRG 540

Query: 189 DGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKSR 248
           D G K + G++G    PA     P P  G    RG RGV           P  +G+P   
Sbjct: 541 DFGLKGEPGRKGEKGEPA----DPGPP-GEPGPRGPRGV-----------PGPEGEPGPP 584

Query: 249 GGRG 252
           G  G
Sbjct: 585 GDPG 588


>gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Homo
           sapiens]
          Length = 1019

 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 72/244 (29%), Positives = 88/244 (36%), Gaps = 43/244 (17%)

Query: 19  PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASARC 78
           PG  GP  + G  G      +   P  P  GV  A+GG   G RG      P+G    R 
Sbjct: 378 PGRRGPPGEIGAKGSKGYQGNSGAPGSP--GVKGAKGGP--GPRG------PKGEPGRRG 427

Query: 79  DGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGV----APPGAM 134
           D G K   G  G    P   +G   P+   GP+   G+ G       RG+     P GA+
Sbjct: 428 DPGTKGSPGSDG----PKGEKGDPGPE---GPRGLAGEVGNKGAKGDRGLPGPRGPQGAL 480

Query: 135 GILRARGGRGT-GSQSPL-----PASLGVPPPPAMGVQRARGGRGVGSESPPRWGCLPTC 188
           G    +G RG  G   P      P   G P  P       RG  G   E  PR       
Sbjct: 481 GEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRG 540

Query: 189 DGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKSR 248
           D G K + G++G    PA     P P  G    RG RGV           P  +G+P   
Sbjct: 541 DFGLKGEPGRKGEKGEPA----DPGPP-GEPGPRGPRGV-----------PGPEGEPGPP 584

Query: 249 GGRG 252
           G  G
Sbjct: 585 GDPG 588


>gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 71/250 (28%), Positives = 85/250 (34%), Gaps = 41/250 (16%)

Query: 15  GASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARG-GRAWGGRGAGSQSLPRGG 73
           G   PG  GPK   G  G         + P    G + A G G   G  G      P G 
Sbjct: 349 GIGKPGFPGPKGDRGMGG-----VPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGP 403

Query: 74  ASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRG-VAPPG 132
             A    GPK +GG  G             PQ   GPK + G  G+   P   G V PPG
Sbjct: 404 PGAIGFPGPKGEGGIVG-------------PQGPPGPKGEPGLQGFPGKPGFLGEVGPPG 450

Query: 133 AMGILRARGGRGTGSQSPLPASLGVPP----------PPAMGVQRARGGRGVGSESPPRW 182
             G+    G +G   Q  +P   GVP           P   G+Q   G  G+G  S P  
Sbjct: 451 MRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGP-- 508

Query: 183 GCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCD 242
              P    GPK + G  G    P  +     P +  L    G+  AL P       P   
Sbjct: 509 -IGPPGIPGPKGEPGLPG----PPGFPGIGKPGVAGLHGPPGKPGALGPQ----GQPGLP 559

Query: 243 GDPKSRGGRG 252
           G P   G  G
Sbjct: 560 GPPGPPGPPG 569



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 60/200 (30%), Positives = 77/200 (38%), Gaps = 24/200 (12%)

Query: 65  GSQSLPRGG-----ASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQG----G 115
           G +++P+ G     AS R + GP+ + G RG    P LP G   P   G P  QG    G
Sbjct: 100 GKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLP-GHGIPGIKGKPGPQGYPGVG 158

Query: 116 KSGWLSVPASRGVAPPGAMGILRARGGRG-TGSQSP--LPASLGVPPPPAMGVQRARGGR 172
           K G   +P       PGAMG+  A+G  G  G   P  +P   G P P  +      GG 
Sbjct: 159 KPGMPGMPGK-----PGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGP 213

Query: 173 GVGSESPPRWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPY 232
           G+  +  P+       D GPK   G +G              A GV    G  G      
Sbjct: 214 GLPGQPGPKG------DRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVG 267

Query: 233 LMGGASPRCDGDPKSRGGRG 252
           L G   P   G P  +G  G
Sbjct: 268 LPGVGKPGVTGFPGPQGPLG 287



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 68/253 (26%), Positives = 87/253 (34%), Gaps = 41/253 (16%)

Query: 15  GASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGA 74
           G   PG  GPK   G  G            P   G+   +G + +G  GA     P G  
Sbjct: 212 GPGLPGQPGPKGDRGPKGL-----------PGPQGLRGPKGDKGFGMPGAPGVKGPPG-- 258

Query: 75  SARCDGGPKSQG----GKRGWLSVPSLPRGGASPQCDGGPKSQG--GKSGWLSVPASRGV 128
                G P   G    GK G    P        P   G P  QG  G  G    P   G+
Sbjct: 259 ---MHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI 315

Query: 129 APPGAMGILRARGGRGTGSQSPLPASLGVPPPPAM---------GVQRARGGRGVGSESP 179
             PG  GI    G  G   +  LP   G+P PP +         G +  RG  GV     
Sbjct: 316 GKPGQDGIPGQPGFPGGKGEQGLP---GLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALG 372

Query: 180 PRWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASP 239
           PR    P    G     G+ G   +P    + P  A+G    +G  G+ + P   G   P
Sbjct: 373 PRGEKGPIGAPGIGGPPGEPGLPGIPGP--MGPPGAIGFPGPKGEGGI-VGP--QGPPGP 427

Query: 240 RCDGDPKSRGGRG 252
           +  G+P  +G  G
Sbjct: 428 K--GEPGLQGFPG 438



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 51/194 (26%), Positives = 64/194 (32%), Gaps = 22/194 (11%)

Query: 18  PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPR--GGAS 75
           P G  GPK + G  G+           PP M  L    G        G   LP   G   
Sbjct: 421 PQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG 480

Query: 76  ARCDGGPKSQGGKRGWLSVPSL--PRGGASPQCDGGPKSQGGKSGWLSVPASRGVAPPGA 133
            + + G     G +G   +P +  P G   P    GPK + G  G    P   G+  PG 
Sbjct: 481 PKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPG---PPGFPGIGKPGV 537

Query: 134 MGILRARG---GRGTGSQSPLPASLG-----------VPPPPAMGVQRARGGRGVGSESP 179
            G+    G     G   Q  LP   G            P PP  G      G G+    P
Sbjct: 538 AGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKP 597

Query: 180 PR-WGCLPTCDGGP 192
           P  +G     +GGP
Sbjct: 598 PHAYGAKKGKNGGP 611



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 65/242 (26%), Positives = 82/242 (33%), Gaps = 50/242 (20%)

Query: 15  GASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGA 74
           G   PGI G     G  G            P AMG+  A+G     G   G   +P    
Sbjct: 139 GHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGE-IGPMGIP---- 193

Query: 75  SARCDGGPKSQGGKRGWLSVPSLPR-GGASPQCDGGPKSQGGKSGWLSVPASRGVAPPGA 133
                 GP+   G  G   +P + + GG       GPK   G  G            PG 
Sbjct: 194 ------GPQGPPGPHG---LPGIGKPGGPGLPGQPGPKGDRGPKGL-----------PGP 233

Query: 134 MGILRARGGRGTGSQSPLPASLGVPPPPAM-GVQRARGGRGVGSESPPRWGCLPTCDGGP 192
            G+   +G +G G    +P + GV  PP M G     G  GVG          P   G P
Sbjct: 234 QGLRGPKGDKGFG----MPGAPGVKGPPGMHGPPGPVGLPGVGK---------PGVTGFP 280

Query: 193 KSQG--GKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKSRGG 250
             QG  GK G    P      P   +GV   +G  G+   P +         G P   GG
Sbjct: 281 GPQGPLGKPGAPGEP-----GPQGPIGVPGVQGPPGI---PGIGKPGQDGIPGQPGFPGG 332

Query: 251 RG 252
           +G
Sbjct: 333 KG 334



 Score = 32.3 bits (72), Expect = 0.41
 Identities = 39/143 (27%), Positives = 46/143 (32%), Gaps = 14/143 (9%)

Query: 19  PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASARC 78
           PGIGGP    G  G         +P PP        G    G  G      P G   A  
Sbjct: 500 PGIGGPSGPIGPPGIPGPKGEPGLPGPP--------GFPGIGKPGVAGLHGPPGKPGAL- 550

Query: 79  DGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAPPGAMGILR 138
             GP+ Q G  G    P  P   A       P+ +      L +    GV PP A G  +
Sbjct: 551 --GPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGID---GVKPPHAYGAKK 605

Query: 139 ARGGRGTGSQSPLPASLGVPPPP 161
            + G          A L  P PP
Sbjct: 606 GKNGGPAYEMPAFTAELTAPFPP 628


>gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 71/250 (28%), Positives = 85/250 (34%), Gaps = 41/250 (16%)

Query: 15  GASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARG-GRAWGGRGAGSQSLPRGG 73
           G   PG  GPK   G  G         + P    G + A G G   G  G      P G 
Sbjct: 349 GIGKPGFPGPKGDRGMGG-----VPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGP 403

Query: 74  ASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRG-VAPPG 132
             A    GPK +GG  G             PQ   GPK + G  G+   P   G V PPG
Sbjct: 404 PGAIGFPGPKGEGGIVG-------------PQGPPGPKGEPGLQGFPGKPGFLGEVGPPG 450

Query: 133 AMGILRARGGRGTGSQSPLPASLGVPP----------PPAMGVQRARGGRGVGSESPPRW 182
             G+    G +G   Q  +P   GVP           P   G+Q   G  G+G  S P  
Sbjct: 451 MRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGP-- 508

Query: 183 GCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCD 242
              P    GPK + G  G    P  +     P +  L    G+  AL P       P   
Sbjct: 509 -IGPPGIPGPKGEPGLPG----PPGFPGIGKPGVAGLHGPPGKPGALGPQ----GQPGLP 559

Query: 243 GDPKSRGGRG 252
           G P   G  G
Sbjct: 560 GPPGPPGPPG 569



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 60/200 (30%), Positives = 77/200 (38%), Gaps = 24/200 (12%)

Query: 65  GSQSLPRGG-----ASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQG----G 115
           G +++P+ G     AS R + GP+ + G RG    P LP G   P   G P  QG    G
Sbjct: 100 GKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLP-GHGIPGIKGKPGPQGYPGVG 158

Query: 116 KSGWLSVPASRGVAPPGAMGILRARGGRG-TGSQSP--LPASLGVPPPPAMGVQRARGGR 172
           K G   +P       PGAMG+  A+G  G  G   P  +P   G P P  +      GG 
Sbjct: 159 KPGMPGMPGK-----PGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGP 213

Query: 173 GVGSESPPRWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPY 232
           G+  +  P+       D GPK   G +G              A GV    G  G      
Sbjct: 214 GLPGQPGPKG------DRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVG 267

Query: 233 LMGGASPRCDGDPKSRGGRG 252
           L G   P   G P  +G  G
Sbjct: 268 LPGVGKPGVTGFPGPQGPLG 287



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 68/253 (26%), Positives = 87/253 (34%), Gaps = 41/253 (16%)

Query: 15  GASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGA 74
           G   PG  GPK   G  G            P   G+   +G + +G  GA     P G  
Sbjct: 212 GPGLPGQPGPKGDRGPKGL-----------PGPQGLRGPKGDKGFGMPGAPGVKGPPG-- 258

Query: 75  SARCDGGPKSQG----GKRGWLSVPSLPRGGASPQCDGGPKSQG--GKSGWLSVPASRGV 128
                G P   G    GK G    P        P   G P  QG  G  G    P   G+
Sbjct: 259 ---MHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI 315

Query: 129 APPGAMGILRARGGRGTGSQSPLPASLGVPPPPAM---------GVQRARGGRGVGSESP 179
             PG  GI    G  G   +  LP   G+P PP +         G +  RG  GV     
Sbjct: 316 GKPGQDGIPGQPGFPGGKGEQGLP---GLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALG 372

Query: 180 PRWGCLPTCDGGPKSQGGKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASP 239
           PR    P    G     G+ G   +P    + P  A+G    +G  G+ + P   G   P
Sbjct: 373 PRGEKGPIGAPGIGGPPGEPGLPGIPGP--MGPPGAIGFPGPKGEGGI-VGP--QGPPGP 427

Query: 240 RCDGDPKSRGGRG 252
           +  G+P  +G  G
Sbjct: 428 K--GEPGLQGFPG 438



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 51/194 (26%), Positives = 64/194 (32%), Gaps = 22/194 (11%)

Query: 18  PPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPR--GGAS 75
           P G  GPK + G  G+           PP M  L    G        G   LP   G   
Sbjct: 421 PQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG 480

Query: 76  ARCDGGPKSQGGKRGWLSVPSL--PRGGASPQCDGGPKSQGGKSGWLSVPASRGVAPPGA 133
            + + G     G +G   +P +  P G   P    GPK + G  G    P   G+  PG 
Sbjct: 481 PKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPG---PPGFPGIGKPGV 537

Query: 134 MGILRARG---GRGTGSQSPLPASLG-----------VPPPPAMGVQRARGGRGVGSESP 179
            G+    G     G   Q  LP   G            P PP  G      G G+    P
Sbjct: 538 AGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKP 597

Query: 180 PR-WGCLPTCDGGP 192
           P  +G     +GGP
Sbjct: 598 PHAYGAKKGKNGGP 611



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 65/242 (26%), Positives = 82/242 (33%), Gaps = 50/242 (20%)

Query: 15  GASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGA 74
           G   PGI G     G  G            P AMG+  A+G     G   G   +P    
Sbjct: 139 GHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGE-IGPMGIP---- 193

Query: 75  SARCDGGPKSQGGKRGWLSVPSLPR-GGASPQCDGGPKSQGGKSGWLSVPASRGVAPPGA 133
                 GP+   G  G   +P + + GG       GPK   G  G            PG 
Sbjct: 194 ------GPQGPPGPHG---LPGIGKPGGPGLPGQPGPKGDRGPKGL-----------PGP 233

Query: 134 MGILRARGGRGTGSQSPLPASLGVPPPPAM-GVQRARGGRGVGSESPPRWGCLPTCDGGP 192
            G+   +G +G G    +P + GV  PP M G     G  GVG          P   G P
Sbjct: 234 QGLRGPKGDKGFG----MPGAPGVKGPPGMHGPPGPVGLPGVGK---------PGVTGFP 280

Query: 193 KSQG--GKRGWLSVPASWVVSPTPAMGVLRARGGRGVALSPYLMGGASPRCDGDPKSRGG 250
             QG  GK G    P      P   +GV   +G  G+   P +         G P   GG
Sbjct: 281 GPQGPLGKPGAPGEP-----GPQGPIGVPGVQGPPGI---PGIGKPGQDGIPGQPGFPGG 332

Query: 251 RG 252
           +G
Sbjct: 333 KG 334



 Score = 32.3 bits (72), Expect = 0.41
 Identities = 39/143 (27%), Positives = 46/143 (32%), Gaps = 14/143 (9%)

Query: 19  PGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVLKARGGRAWGGRGAGSQSLPRGGASARC 78
           PGIGGP    G  G         +P PP        G    G  G      P G   A  
Sbjct: 500 PGIGGPSGPIGPPGIPGPKGEPGLPGPP--------GFPGIGKPGVAGLHGPPGKPGAL- 550

Query: 79  DGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQGGKSGWLSVPASRGVAPPGAMGILR 138
             GP+ Q G  G    P  P   A       P+ +      L +    GV PP A G  +
Sbjct: 551 --GPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGID---GVKPPHAYGAKK 605

Query: 139 ARGGRGTGSQSPLPASLGVPPPP 161
            + G          A L  P PP
Sbjct: 606 GKNGGPAYEMPAFTAELTAPFPP 628


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.138    0.456 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,987,844
Number of Sequences: 37866
Number of extensions: 1176991
Number of successful extensions: 7191
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 120
Number of HSP's successfully gapped in prelim test: 749
Number of HSP's that attempted gapping in prelim test: 4361
Number of HSP's gapped (non-prelim): 2148
length of query: 255
length of database: 18,247,518
effective HSP length: 100
effective length of query: 155
effective length of database: 14,460,918
effective search space: 2241442290
effective search space used: 2241442290
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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