Guide to the Human Genome
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Search of human proteins with 239755454

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239755454 PREDICTED: hypothetical protein [Homo sapiens]
         (305 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239755454 PREDICTED: hypothetical protein [Homo sapiens]           648   0.0  
gi|239744258 PREDICTED: hypothetical protein LOC100128703 [Homo ...   590   e-169
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]    80   3e-15
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       77   2e-14
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       76   4e-14
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    76   4e-14
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    76   4e-14
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    76   4e-14
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      74   2e-13
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    73   3e-13
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    73   3e-13
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]     73   4e-13
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]      72   6e-13
gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]               72   8e-13
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    71   1e-12
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    71   1e-12
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    71   1e-12
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]                71   1e-12
gi|5803080 macrophage receptor with collagenous structure [Homo ...    70   2e-12
gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [H...    70   2e-12
gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Ho...    70   2e-12
gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Hom...    70   2e-12
gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]       69   4e-12
gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s...    69   5e-12
gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s...    69   5e-12
gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo ...    69   5e-12
gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]        69   5e-12
gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]        69   5e-12
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          69   7e-12
gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]        69   7e-12

>gi|239755454 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 305

 Score =  648 bits (1672), Expect = 0.0
 Identities = 305/305 (100%), Positives = 305/305 (100%)

Query: 1   MTPSRAQEGPPRVERAECGASAGALTIVSSHGGDSDKDLCARTQIYGAQPREDQMGSVEK 60
           MTPSRAQEGPPRVERAECGASAGALTIVSSHGGDSDKDLCARTQIYGAQPREDQMGSVEK
Sbjct: 1   MTPSRAQEGPPRVERAECGASAGALTIVSSHGGDSDKDLCARTQIYGAQPREDQMGSVEK 60

Query: 61  LTTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVAS 120
           LTTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVAS
Sbjct: 61  LTTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVAS 120

Query: 121 PGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQK 180
           PGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQK
Sbjct: 121 PGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQK 180

Query: 181 GECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECG 240
           GECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECG
Sbjct: 181 GECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECG 240

Query: 241 VPWREGAVWRPLDRRGSVASPGEKGECGVRWREGRVWYSLDKRGSVPAALASQRHALLAL 300
           VPWREGAVWRPLDRRGSVASPGEKGECGVRWREGRVWYSLDKRGSVPAALASQRHALLAL
Sbjct: 241 VPWREGAVWRPLDRRGSVASPGEKGECGVRWREGRVWYSLDKRGSVPAALASQRHALLAL 300

Query: 301 PQPQG 305
           PQPQG
Sbjct: 301 PQPQG 305


>gi|239744258 PREDICTED: hypothetical protein LOC100128703 [Homo
           sapiens]
          Length = 389

 Score =  590 bits (1521), Expect = e-169
 Identities = 276/286 (96%), Positives = 279/286 (97%)

Query: 1   MTPSRAQEGPPRVERAECGASAGALTIVSSHGGDSDKDLCARTQIYGAQPREDQMGSVEK 60
           MTPSRAQEGPPRVERAECGASAGALTIVSSHGGDSDKDLCARTQIYGAQPREDQMGSVEK
Sbjct: 1   MTPSRAQEGPPRVERAECGASAGALTIVSSHGGDSDKDLCARTQIYGAQPREDQMGSVEK 60

Query: 61  LTTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVAS 120
           LTTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVAS
Sbjct: 61  LTTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVAS 120

Query: 121 PGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQK 180
           PGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQK
Sbjct: 121 PGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQK 180

Query: 181 GECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECG 240
           GECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECG
Sbjct: 181 GECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECG 240

Query: 241 VPWREGAVWRPLDRRGSVASPGEKGECGVRWREGRVWYSLDKRGSV 286
           VPWREG VWRPL+RRGSVASPGEKGECGV W EG VW  L++R SV
Sbjct: 241 VPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASV 286



 Score =  433 bits (1114), Expect = e-122
 Identities = 195/212 (91%), Positives = 201/212 (94%)

Query: 94  GEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKG 153
           G+KGECG+PW EG VWRPLERR SVASPGEKGECGVPWREGRVWRPL+RR SVASPG+KG
Sbjct: 178 GQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKG 237

Query: 154 ECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVASPGEKGECGV 213
           ECGVPWREG VWRPLERR SVASPG+KGECGVPW EGGVWRPLERR SVASPGEKGECGV
Sbjct: 238 ECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGV 297

Query: 214 PWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWRE 273
           PW EG VWRPLERRASVASPG+KGECGVPWREG VWRPLDRRGSVASPGEKGECGVRWRE
Sbjct: 298 PWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWRE 357

Query: 274 GRVWYSLDKRGSVPAALASQRHALLALPQPQG 305
           GRVWYSLDKRGSVPAALASQRHALLALPQPQG
Sbjct: 358 GRVWYSLDKRGSVPAALASQRHALLALPQPQG 389


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score = 79.7 bits (195), Expect = 3e-15
 Identities = 66/215 (30%), Positives = 91/215 (42%), Gaps = 13/215 (6%)

Query: 68  SAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGEC 127
           SA P   P PR ++   G  G     GEKGE G P  +G V    + +    +PG +GE 
Sbjct: 702 SAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGD-QGKPGAPGPRGED 760

Query: 128 GVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPW 187
           G    +G+  +     G   S GEKG+ GVP   G   RP   + S+  PG  G  G   
Sbjct: 761 GPEGPKGQAGQ-AGEEGPPGSAGEKGKLGVPGLPGYPGRP-GPKGSIGFPGPLGPIGEKG 818

Query: 188 REGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGA 247
           + G   +P    G    PG +GE G P   G+   P        +PG  GE G+P  +G 
Sbjct: 819 KSGKTGQP-GLEGERGPPGSRGERGQPGATGQP-GPKGDVGQDGAPGIPGEKGLPGLQGP 876

Query: 248 VWRP--------LDRRGSVASPGEKGECGVRWREG 274
              P          + G    PG++GE G + + G
Sbjct: 877 PGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTG 911



 Score = 76.3 bits (186), Expect = 3e-14
 Identities = 64/201 (31%), Positives = 84/201 (41%), Gaps = 29/201 (14%)

Query: 85  GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
           GE G   +AGEKG+ G+P   G   RP   + S+  PG  G  G   + G+  +P    G
Sbjct: 773 GEEGPPGSAGEKGKLGVPGLPGYPGRP-GPKGSIGFPGPLGPIGEKGKSGKTGQP-GLEG 830

Query: 145 SVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLER-----R 199
               PG +GE G P   G              PG KG+ G   ++G    P E+     +
Sbjct: 831 ERGPPGSRGERGQPGATG-------------QPGPKGDVG---QDGAPGIPGEKGLPGLQ 874

Query: 200 GSVASPGEKGECGVPWREGRVWRPLER-----RASVASPGQKGECGVPWREGAVWRPLDR 254
           G    PG KG  G   ++GR   P +R     +     PG  G  G   + G V  PL  
Sbjct: 875 GPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVG-PLGE 933

Query: 255 RGSVASPGEKGECGVRWREGR 275
           RG    PG  GE G+   EGR
Sbjct: 934 RGPPGPPGPPGEQGLPGLEGR 954



 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 68/228 (29%), Positives = 89/228 (39%), Gaps = 30/228 (13%)

Query: 75  PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLE-----------------RRAS 117
           P PR L    G  G +   G  G  G P  +G V  P E                  +  
Sbjct: 598 PGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGL 657

Query: 118 VASPGEKGECGVPWREGRVWR--PLDRRGSVASPGEKGECGVPWREG--------GVWRP 167
           + +PGEKG  G P   G      PL   G     GEKG  G P   G        GV   
Sbjct: 658 IGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGT 717

Query: 168 LERRASVASPGQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERR 227
              R      G+KGE G P  +G V    + +G   +PG +GE G    +G+  +  E  
Sbjct: 718 SGNRGLQGEKGEKGEDGFPGFKGDVGLKGD-QGKPGAPGPRGEDGPEGPKGQAGQAGE-E 775

Query: 228 ASVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREGR 275
               S G+KG+ GVP   G   RP   +GS+  PG  G  G + + G+
Sbjct: 776 GPPGSAGEKGKLGVPGLPGYPGRP-GPKGSIGFPGPLGPIGEKGKSGK 822



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 68/220 (30%), Positives = 88/220 (40%), Gaps = 29/220 (13%)

Query: 72   GSVPAPRPLRSID--GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECG- 128
            GS+  P PL  I   G++G +   G +GE G P + G+  +P     +   PG KG+ G 
Sbjct: 803  GSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQP----GATGQPGPKGDVGQ 858

Query: 129  --VPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLER-----RASVASPGQKG 181
               P   G    P   +G    PG KG  G   ++G    P +R     +     PG  G
Sbjct: 859  DGAPGIPGEKGLP-GLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAG 917

Query: 182  ECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWR--------PLERRASV--- 230
              G   + G V  PL  RG    PG  GE G+P  EGR           PL +       
Sbjct: 918  VLGPQGKTGEVG-PLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLR 976

Query: 231  ASPGQKGECGVPWREGAVW--RPLDRRGSVASPGEKGECG 268
              PG KG  G P   G      P    G+  SPGE+G  G
Sbjct: 977  GFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLG 1016



 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 65/201 (32%), Positives = 77/201 (38%), Gaps = 25/201 (12%)

Query: 68   SAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGEC 127
            S +PG+ P P   R   G  G     GEKG  G P  +G              PG  G  
Sbjct: 1300 SGEPGA-PGPPGKRGPSGHMGREGREGEKGAKGEPGPDG-------------PPGRTGPM 1345

Query: 128  GVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPW 187
            G     GRV  P   RG     GE G  G P + G    P         PG KG+ G P 
Sbjct: 1346 GARGPPGRV-GPEGLRGIPGPVGEPGLLGAPGQMG----PPGPLGPSGLPGLKGDTG-PK 1399

Query: 188  REGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGA 247
             E G    +   G     GEKG+ G+P  +G    P   +     PG  G  G P   G 
Sbjct: 1400 GEKGHIGLIGLIGPPGEAGEKGDQGLPGVQG----PPGPKGDPGPPGPIGSLGHPGPPG- 1454

Query: 248  VWRPLDRRGSVASPGEKGECG 268
            V  PL ++GS  SPG  G  G
Sbjct: 1455 VAGPLGQKGSKGSPGSMGPRG 1475



 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 66/226 (29%), Positives = 85/226 (37%), Gaps = 30/226 (13%)

Query: 71   PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
            P   P P       G  G     G+KG+ G+    G +  P   +     PGEKGE G  
Sbjct: 1107 PAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPP-GLQGLPGPPGEKGEVGDV 1165

Query: 131  WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRP-----LERRASVASPGQKGECGV 185
               G    P   RG     G +G  G+P   GGV +P        R     PG  G  G+
Sbjct: 1166 GSMGPHGAP-GPRGPQGPTGSEGTPGLP---GGVGQPGAVGEKGERGDAGDPGPPGAPGI 1221

Query: 186  PWREG-----------GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASV--AS 232
            P  +G           G   P  ++G     G KG  G     G +  P +   S    S
Sbjct: 1222 PGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGS 1281

Query: 233  PGQKGE---CGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREGR 275
            PG+KG+    G P   GA   P    G+   PG++G  G   REGR
Sbjct: 1282 PGEKGDPGDVGGPGPPGASGEP----GAPGPPGKRGPSGHMGREGR 1323



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 62/221 (28%), Positives = 81/221 (36%), Gaps = 36/221 (16%)

Query: 74   VPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWRE 133
            +P P       G AG S   G+KG+ G P  +G             S G+KG+ G P + 
Sbjct: 1056 IPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKG-------------SKGDKGDAGPPGQP 1102

Query: 134  GRVWRPLDRRGSVASPGEKGECGVPWREG-----------GVWRPLERRASVASPGQKGE 182
            G +  P    G   + G +G  G P   G           GV  P   +     PG+KGE
Sbjct: 1103 G-IRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGE 1161

Query: 183  CG-----VPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKG 237
             G      P    G   P    GS  +PG  G  G P   G        R     PG  G
Sbjct: 1162 VGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGE----KGERGDAGDPGPPG 1217

Query: 238  ECGVPWREGAVWRPLDR--RGSVASPGEKGECGVRWREGRV 276
              G+P  +G +    D    G+   PG+KG  G    +G V
Sbjct: 1218 APGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSV 1258


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 70/222 (31%), Positives = 92/222 (41%), Gaps = 22/222 (9%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLER-----RASVASPGEKG 125
           P   P P  +  +DG+ G     G +GE G P   GQ   P  +     + ++  PGEKG
Sbjct: 689 PPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPP---GQQGNPGAQGLPGPQGAIGPPGEKG 745

Query: 126 ECGVPWREGRVWR--PLDRRGSVASPGEKGECGVPWREGGVWRPLER--------RASVA 175
             G P   G      P    G    PGEKG  G P  +G +  P  R        R    
Sbjct: 746 PLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKG 805

Query: 176 SPGQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQ 235
           + G+KGE G P  +G +    + RG +  PG +GE G    +GR   P      +  PG+
Sbjct: 806 TKGEKGEDGFPGFKGDMGIKGD-RGEIGPPGPRGEDGPEGPKGR-GGPNGDPGPLGPPGE 863

Query: 236 KGECGVPWREGAVWR--PLDRRGSVASPGEKGECGVRWREGR 275
           KG+ GVP   G   R  P    G    PG  GE G R   G+
Sbjct: 864 KGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGK 905



 Score = 75.1 bits (183), Expect = 7e-14
 Identities = 67/219 (30%), Positives = 94/219 (42%), Gaps = 27/219 (12%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
           P   P PR ++  DG  G     GEKGE G P  +G +    + R  +  PG +GE G  
Sbjct: 785 PIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGD-RGEIGPPGPRGEDGPE 843

Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASP------GQKGECG 184
             +GR   P    G +  PGEKG+ GVP   G   R    + S+  P      G+KG  G
Sbjct: 844 GPKGR-GGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQ-GPKGSIGFPGFPGANGEKGGRG 901

Query: 185 VPWREGGVWRPLERRGSVASPGEKGECGVPWR---------EGRVWRPLERRASVASPGQ 235
            P + G    P  +RG     GE+G  G+  +         +G    P ER  +    G 
Sbjct: 902 TPGKPG----PRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPN----GP 953

Query: 236 KGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREG 274
           +G  G P  +G    P  + G    PG++GE G + + G
Sbjct: 954 QGPTGFPGPKGPPGPP-GKDGLPGHPGQRGETGFQGKTG 991



 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 65/218 (29%), Positives = 86/218 (39%), Gaps = 24/218 (11%)

Query: 72   GSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPW 131
            G  P P+  R   GE+G S AAG  G  G P  +G    P      V  PG+ G  G P 
Sbjct: 1299 GGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSP----GPVGFPGDPGPPGEPG 1354

Query: 132  REGRVWRPLDR--------RGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKG 181
              G+   P D+         GS    GE G  G P + G  G   P  R+    + G+ G
Sbjct: 1355 PAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAG 1414

Query: 182  ECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGV 241
              G P + G    P+  +G+   PG  G  G+P   G    P         PG  G  G+
Sbjct: 1415 LEGPPGKTG----PIGPQGAPGKPGPDGLRGIPGPVGEQGLP-GSPGPDGPPGPMGPPGL 1469

Query: 242  PWREGAVWRPLDRR-----GSVASPGEKGECGVRWREG 274
            P  +G      ++      G +  PGE+GE G R   G
Sbjct: 1470 PGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1507



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 59/195 (30%), Positives = 78/195 (40%), Gaps = 34/195 (17%)

Query: 85   GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWR---PLD 141
            GE GH    G  GE G+P   G+            + G+ G  G+P ++G       P D
Sbjct: 1012 GERGHPGPPGPPGEQGLPGLAGKE----------GTKGDPGPAGLPGKDGPPGLRGFPGD 1061

Query: 142  RR--GSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERR 199
            R   G V + G KG  G P   G    P ER  +    G  G  G+P R G    P    
Sbjct: 1062 RGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPA----GAAGPIGIPGRPGPQGPP-GPA 1116

Query: 200  GSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVA 259
            G   +PGEKG  G   R+G        +  V  PG  G  G P  +G        +G + 
Sbjct: 1117 GEKGAPGEKGPQGPAGRDGL-------QGPVGLPGPAGPVGPPGEDGD-------KGEIG 1162

Query: 260  SPGEKGECGVRWREG 274
             PG+KG  G +  +G
Sbjct: 1163 EPGQKGSKGDKGEQG 1177



 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 62/197 (31%), Positives = 80/197 (40%), Gaps = 20/197 (10%)

Query: 85   GEAGHSEAAGEKGECGIPWT---EGQVWRPLERRASVASPGEKGECGVPWREGRVWR--- 138
            GE G   + G+KGE G P     +G + +P    A    PG +G+ G+  ++G       
Sbjct: 1162 GEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGAD-GEPGPRGQQGLFGQKGDEGPRGF 1220

Query: 139  -----PLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVW 193
                 P+  +G    PGEKGE G   + G    P  R  S  +PG  G  G P   GG+ 
Sbjct: 1221 PGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPS-GAPGADGPQGPP---GGIG 1276

Query: 194  RPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVW--RP 251
             P    G    PGE GE G+P  EG    P   R      G  G  G P  +G      P
Sbjct: 1277 NP-GAVGEKGEPGEAGEPGLP-GEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGP 1334

Query: 252  LDRRGSVASPGEKGECG 268
                G V  PG+ G  G
Sbjct: 1335 KGSPGPVGFPGDPGPPG 1351



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 64/226 (28%), Positives = 84/226 (37%), Gaps = 42/226 (18%)

Query: 71   PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
            PG      P  SI G  G   A GEKG  G P   G    P  +R      GE+G  G+ 
Sbjct: 873  PGYPGRQGPKGSI-GFPGFPGANGEKGGRGTPGKPG----PRGQRGPTGPRGERGPRGIT 927

Query: 131  WR---------EGRVWRPLDR-----RGSVASPGEKGECGVPWREGGVWRPLER-----R 171
             +         +G    P +R     +G    PG KG  G P ++G    P +R     +
Sbjct: 928  GKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 987

Query: 172  ASVASPGQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVA 231
                 PG  G  G P    G   P+  RG    PG  GE G+P   G+            
Sbjct: 988  GKTGPPGPPGVVG-PQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGK----------EG 1036

Query: 232  SPGQKGECGVPWREGAVWRPLDRRGSVAS---PGEKGECGVRWREG 274
            + G  G  G+P ++G    P   RG       PG  G  G++  EG
Sbjct: 1037 TKGDPGPAGLPGKDG----PPGLRGFPGDRGLPGPVGALGLKGNEG 1078



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 62/216 (28%), Positives = 79/216 (36%), Gaps = 30/216 (13%)

Query: 71   PGSVPAPRPLRSIDGEAGHSEAAGEK------GECGIPWTEGQVWRPLERRASVASPGEK 124
            P   P     +   G  G+  A GEK      GE G+P  EG    P   R      G  
Sbjct: 1259 PSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLP-GEGGPPGPKGERGEKGESGPS 1317

Query: 125  GECGVPWREGRVW--RPLDRRGSVASPGEKGECGVPWREGGVWRPLER-----RASVASP 177
            G  G P  +G      P    G V  PG+ G  G P   G    P ++          SP
Sbjct: 1318 GAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSP 1377

Query: 178  GQKGE---CGVPWREG--GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVAS 232
            G  GE    G P + G  G   P  R+G   + GE G  G P + G    P+  + +   
Sbjct: 1378 GPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTG----PIGPQGAPGK 1433

Query: 233  PGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECG 268
            PG  G  G+P        P+  +G   SPG  G  G
Sbjct: 1434 PGPDGLRGIP-------GPVGEQGLPGSPGPDGPPG 1462



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 58/188 (30%), Positives = 73/188 (38%), Gaps = 10/188 (5%)

Query: 83  IDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDR 142
           I+G  G    AG  G  G     GQV  P E R     PG  G  G+P   G +     R
Sbjct: 467 IEGPPGPEGPAGLPGPPGTMGPTGQVGDPGE-RGPPGRPGLPGADGLPGPPGTMLMLPFR 525

Query: 143 RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLE--RRG 200
            G     G KG   V  +E    + + ++A +A  G  G  G+  R G V  P     +G
Sbjct: 526 FGGGGDAGSKGPM-VSAQESQA-QAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKG 583

Query: 201 SVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVAS 260
                G +G  GV    G   +P  RR    S G +G  G    +G   R  D  G    
Sbjct: 584 EPGDVGPQGPRGVQGPPGPAGKP-GRRGRAGSDGARGMPGQTGPKGD--RGFD--GLAGL 638

Query: 261 PGEKGECG 268
           PGEKG  G
Sbjct: 639 PGEKGHRG 646



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 49/164 (29%), Positives = 62/164 (37%), Gaps = 38/164 (23%)

Query: 68   SAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGEC 127
            S  P   P P     + G  G S   GEKG  G+    G +  P E+       GEKG+ 
Sbjct: 1454 SPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGL---IGLIGPPGEQ-------GEKGDR 1503

Query: 128  GVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPW 187
            G+P  +G             S G KGE G+    G           +  PG  G  G P 
Sbjct: 1504 GLPGPQG-------------SSGPKGEQGITGPSG----------PIGPPGPPGLPGPPG 1540

Query: 188  REG--GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRAS 229
             +G  G   P   +G    PG  G  G P   G V +PL  +AS
Sbjct: 1541 PKGAKGSSGPTGPKGEAGHPGPPGPPGPP---GEVIQPLPIQAS 1581



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 61/242 (25%), Positives = 78/242 (32%), Gaps = 50/242 (20%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRP------------------- 111
           P  +P P       G+ G     G  G  G+P  +G    P                   
Sbjct: 476 PAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSK 535

Query: 112 -------------LERRASVASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVP 158
                        + ++A +A  G  G  G+  R G V  P    GS    GE G+ G P
Sbjct: 536 GPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPP----GSGGLKGEPGDVG-P 590

Query: 159 WREGGVWRPLERRASVASPGQKGECGVPWREG--GVWRPLERR---GSVASPGEKGECGV 213
               GV  P         PG++G  G     G  G   P   R   G    PGEKG  G 
Sbjct: 591 QGPRGVQGP---PGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGD 647

Query: 214 PWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWRE 273
           P   G    P +        G+ G  G+P   G    P    G    PG  G  GV   +
Sbjct: 648 PGPSGPPGPPGD-DGERGDDGEVGPRGLPGEPG----PRGLLGPKGPPGPPGPPGVTGMD 702

Query: 274 GR 275
           G+
Sbjct: 703 GQ 704


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 70/209 (33%), Positives = 89/209 (42%), Gaps = 24/209 (11%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRP----LERRASVASP-GEKG 125
           PGS   P P +   GE G   ++G KG  G P   G+   P    L     V  P G+ G
Sbjct: 530 PGSDGLPGP-KGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLG 588

Query: 126 ECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGV 185
             G P  +GR   P    GS+   G+ G  G+P  +G    P         PG+ G  GV
Sbjct: 589 PLGAPGEDGRPGPP----GSIGIRGQPGSMGLPGPKGSSGDP-------GKPGEAGNAGV 637

Query: 186 PWREGGVWRPLE--RRGSVASPG---EKGECGVPWREGRVWRPLERRASVASPGQKGECG 240
           P + G   +  E    G V  PG   E+GE G P   G    P          G+ G+ G
Sbjct: 638 PGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLP-GPPGPPGEGGKPGDQG 696

Query: 241 VPWREGAVWRPLDRRGSVASPGEKGECGV 269
           VP   GAV  PL  RG   +PGE+GE G+
Sbjct: 697 VPGDPGAVG-PLGPRGERGNPGERGEPGI 724



 Score = 68.2 bits (165), Expect = 9e-12
 Identities = 62/213 (29%), Positives = 86/213 (40%), Gaps = 32/213 (15%)

Query: 68  SAKPGS--VPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKG 125
           +  PG+   P    L  + G  GH    G KGE G P ++G+          + + G  G
Sbjct: 281 AGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEA----GPTGPMGAMGPLG 336

Query: 126 ECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRAS---VASPGQKGE 182
             G+P   GR+       G   +PG++G  G+P + G +  PL    S     +PG KGE
Sbjct: 337 PRGMPGERGRL-------GPQGAPGQRGAHGMPGKPGPM-GPLGIPGSSGFPGNPGMKGE 388

Query: 183 CGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVP 242
            G P    G   P  +RG    PG  G  G+P   G          +  +PG KG  G P
Sbjct: 389 AG-PTGARGPEGPQGQRGETGPPGPVGSPGLPGAIG----------TDGTPGAKGPTGSP 437

Query: 243 WREGAVWRPLDRRGSVASPGEKGECGVRWREGR 275
              G    P    G   SPG +G  G +   G+
Sbjct: 438 GTSG----PPGSAGPPGSPGPQGSTGPQGIRGQ 466



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 74/258 (28%), Positives = 91/258 (35%), Gaps = 43/258 (16%)

Query: 75   PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
            P P     + G  G     G  G  G P + G+V  P        +PG  G  G P +EG
Sbjct: 884  PGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPP----GPAGAPGPAGPLGEPGKEG 939

Query: 135  RVWRPLD--------RRGSVASPGEKGECGVPWREG--------GVWRPLERRASVASPG 178
                  D         RG    PG  G+ G P  +G        G      +R  V  PG
Sbjct: 940  PPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPG 999

Query: 179  QKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGE 238
            Q+GE G+P   G    P    G V   G  G+ G P   G    P      V  PG +G 
Sbjct: 1000 QRGERGMPGLPGPAGTP----GKVGPTGATGDKGPPGPVG----PPGSNGPVGEPGPEGP 1051

Query: 239  C---GVPWREGAVWRPLDR--------RGSVASPGEKGECGVRWREGRVWYSLDKRGSVP 287
                G P R+GAV    DR         GS  +PG  G  G     G+      +    P
Sbjct: 1052 AGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGP 1111

Query: 288  AALASQRHALLALPQPQG 305
               A +R     LP PQG
Sbjct: 1112 PGRAGKR----GLPGPQG 1125



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 60/196 (30%), Positives = 77/196 (39%), Gaps = 27/196 (13%)

Query: 85  GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRP--LDR 142
           G  G     G+ G  G+P  +G    P         PGE G  GVP + G   +   +  
Sbjct: 600 GPPGSIGIRGQPGSMGLPGPKGSSGDP-------GKPGEAGNAGVPGQRGAPGKDGEVGP 652

Query: 143 RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG-----GVWRPLE 197
            G V  PG  GE G    E G   P   +     PG  GE G P  +G     G   PL 
Sbjct: 653 SGPVGPPGLAGERG----EQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLG 708

Query: 198 RRGSVASPGEKGE---CGVPWREGRV--WRPLERRASVASPGQKGECGVPWREGAVWRPL 252
            RG   +PGE+GE    G+P  +G      P   + S    G  G+ G P  +G      
Sbjct: 709 PRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMP---- 764

Query: 253 DRRGSVASPGEKGECG 268
             RG   +PG KG+ G
Sbjct: 765 GERGIAGTPGPKGDRG 780



 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 67/219 (30%), Positives = 77/219 (35%), Gaps = 31/219 (14%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
           PG V +P     + G  G     G KG  G P T G    P        SPG +G  G  
Sbjct: 410 PGPVGSP----GLPGAIGTDGTPGAKGPTGSPGTSG----PPGSAGPPGSPGPQGSTGPQ 461

Query: 131 WREGRVWRP--LDRRGSVASPGEKGECGV-----PWREGGVWRPLERRASVASPGQKGEC 183
              G+   P     +G     GE G  G+     P  E G   P     +V  PG  GE 
Sbjct: 462 GIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGER 521

Query: 184 GVPWREG--------GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQ 235
           G P   G        G       RG V S G KG  G P R G    P  R       G 
Sbjct: 522 GAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGAR-------GL 574

Query: 236 KGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREG 274
            G  GV   EG +  PL   G    PG  G  G+R + G
Sbjct: 575 TGNPGVQGPEGKLG-PLGAPGEDGRPGPPGSIGIRGQPG 612



 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 75/229 (32%), Positives = 89/229 (38%), Gaps = 34/229 (14%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRP----------LER--RASV 118
           PGS   PR  R   G  G     G  GE G+P   G    P          L R   A +
Sbjct: 137 PGS-QGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQM 195

Query: 119 ASPGEKGECG-----VPWREGRVWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERR 171
           A   EK   G     +P   G V  P   +G     G  G  G P   G  G   P+  R
Sbjct: 196 AGLDEKSGLGSQVGLMPGSVGPV-GPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSR 254

Query: 172 ASVASPGQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREG----RVWRPLE-R 226
                PG+ GE G P R G    P E  G   SPG +G  G P   G    R  + LE  
Sbjct: 255 GPEGPPGKPGEDGEPGRNG---NPGE-VGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGP 310

Query: 227 RASVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREGR 275
           +  V +PG KGE G     GA+  PL  RG    PGE+G  G +   G+
Sbjct: 311 KGEVGAPGSKGEAGPTGPMGAM-GPLGPRG---MPGERGRLGPQGAPGQ 355



 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 64/216 (29%), Positives = 81/216 (37%), Gaps = 25/216 (11%)

Query: 70  KPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGV 129
           +PG VP    +R   G AG   + G +GE G     G    P   +     PG  G+ G 
Sbjct: 117 EPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPG----PRGPQGIDGEPGVPGQPGA 172

Query: 130 PWREGRVWRP----LDRRGSVASPGEKGECGVPWREG---GVWRPLERRASVASPGQKGE 182
           P   G    P    L R  S    G   + G+  + G   G   P+  R      GQ+G 
Sbjct: 173 PGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGG 232

Query: 183 CGVPWREG-----GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKG 237
            G     G     G   P+  RG    PG+ GE G P R G    P E      SPG +G
Sbjct: 233 AGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNG---NPGE-VGFAGSPGARG 288

Query: 238 ECGVPWREGAVWRPLDR-----RGSVASPGEKGECG 268
             G P   G       +     +G V +PG KGE G
Sbjct: 289 FPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAG 324



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 59/212 (27%), Positives = 74/212 (34%), Gaps = 43/212 (20%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
           P   P P       G  G     GE+G  G P  +G        R  +   G +G  G  
Sbjct: 742 PKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGD-------RGGIGEKGAEGTAGND 794

Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGV----- 185
              G +  PL   G     GEKGE G      G+  P   R +  S G+ G  G      
Sbjct: 795 GARG-LPGPLGPPGPAGPTGEKGEPG----PRGLVGPPGSRGNPGSRGENGPTGAVGFAG 849

Query: 186 ---PWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVP 242
              P  + GV      +G    PG+KG+ G P  +G             SPG  G  GVP
Sbjct: 850 PQGPDGQPGV------KGEPGEPGQKGDAGSPGPQG----------LAGSPGPHGPNGVP 893

Query: 243 WREGAVWRPLDRRGSVASPGEKGECGVRWREG 274
             +G        RG+   PG  G  G   R G
Sbjct: 894 GLKGG-------RGTQGPPGATGFPGSAGRVG 918



 Score = 35.4 bits (80), Expect = 0.063
 Identities = 33/117 (28%), Positives = 43/117 (36%), Gaps = 15/117 (12%)

Query: 74   VPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWRE 133
            +P P+  R   G+ G     G+KG  G    +G    P          GE+G  G+P   
Sbjct: 1120 LPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPP-------GPNGEQGSAGIP--- 1169

Query: 134  GRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
                 P   RG     G  G+ G P   G +  P   R SV   G +G  G P   G
Sbjct: 1170 ----GPFGPRGPPGPVGPSGKEGNPGPLGPIGPP-GVRGSVGEAGPEGPPGEPGPPG 1221


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein
           [Homo sapiens]
          Length = 1650

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 68/214 (31%), Positives = 88/214 (41%), Gaps = 17/214 (7%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
           P   P PR ++ +DG  G     GEKGE G P  +G +    + R  V  PG +GE G  
Sbjct: 627 PLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGD-RGEVGVPGSRGEDGPE 685

Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGV--- 185
             +GR   P    G     GEKG+ GVP   G  G   P         PG  GE G    
Sbjct: 686 GPKGRT-GPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 744

Query: 186 -----PWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECG 240
                P  E G   P  +RG   + G+ G  G    +G    P ER      PG +G  G
Sbjct: 745 SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGER----GLPGPQGPNG 800

Query: 241 VPWREGAVWRPLDRRGSVASPGEKGECGVRWREG 274
            P  +G    P  + G    PG++GE G + + G
Sbjct: 801 FPGPKGPPGPP-GKDGLPGHPGQRGEVGFQGKTG 833



 Score = 69.3 bits (168), Expect = 4e-12
 Identities = 68/222 (30%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLER-----RASVASPGEKG 125
           P  +P P  +R +DG  G   + G +GE G P   GQ   P  +     + ++   GEKG
Sbjct: 531 PPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP---GQQGTPGTQGLPGPQGAIGPHGEKG 587

Query: 126 ECGVPWREGRVWR--PLDRRGSVASPGEKGECGVPWREGGVWRPLER--------RASVA 175
             G P   G      P    G    PG KG  G    +G +  P  R        R    
Sbjct: 588 PQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKG 647

Query: 176 SPGQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQ 235
             G+KGE G P  +G +    + RG V  PG +GE G    +GR   P          G+
Sbjct: 648 HKGEKGEDGFPGFKGDIGVKGD-RGEVGVPGSRGEDGPEGPKGRT-GPTGDPGPPGLMGE 705

Query: 236 KGECGVPWREGAVWR--PLDRRGSVASPGEKGECGVRWREGR 275
           KG+ GVP   G   R  P    G    PG  GE G R   G+
Sbjct: 706 KGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGK 747



 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 63/224 (28%), Positives = 84/224 (37%), Gaps = 48/224 (21%)

Query: 70   KPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGV 129
            +PG   +P P     GE G     G++G  G P +EG       R+    + G+ G  G 
Sbjct: 1212 EPGQPGSPGPT----GENGPPGPLGKRGPAGSPGSEG-------RQGGKGAKGDPGAIGA 1260

Query: 130  PWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWRE 189
            P + G    P+   G    PG  G  G+P   G   RP         PG  G  G+P   
Sbjct: 1261 PGKTG----PVGPAGPAGKPGPDGLRGLPGSVGQQGRP-GATGQAGPPGPVGPPGLPGLR 1315

Query: 190  GGVWRPLERR--------GSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGV 241
            G      E+         G     GEKG+ G+P  +G             SPGQKGE G+
Sbjct: 1316 GDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQG-------------SPGQKGEMGI 1362

Query: 242  PWREGAVW-----------RPLDRRGSVASPGEKGECGVRWREG 274
            P   G +             P   +G+    G KGE GV+   G
Sbjct: 1363 PGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPG 1406



 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 60/193 (31%), Positives = 76/193 (39%), Gaps = 30/193 (15%)

Query: 85   GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
            GE GH    G  GE G+P T G+            + G+ G  G P ++G    P   RG
Sbjct: 854  GERGHPGPPGPPGEQGLPGTAGK----------EGTKGDPGPPGAPGKDG----PAGLRG 899

Query: 145  SVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVAS 204
                 G  G  G P  +G    P        SPG++G  G     GG   P  R G    
Sbjct: 900  FPGERGLPGTAGGPGLKGNE-GPSGPPGPAGSPGERGAAG----SGGPIGPPGRPGPQGP 954

Query: 205  PGEKGECGVPWREGRVWRPLER---RASVASPGQKGECGVPWREGAVWRPLDRRGSVASP 261
            PG  GE GVP  +G +  P  R   +  V  PG  G  GV   +G        +G V  P
Sbjct: 955  PGAAGEKGVPGEKGPI-GPTGRDGVQGPVGLPGPAGPPGVAGEDG-------DKGEVGDP 1006

Query: 262  GEKGECGVRWREG 274
            G+KG  G +   G
Sbjct: 1007 GQKGTKGNKGEHG 1019



 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 69/240 (28%), Positives = 89/240 (37%), Gaps = 37/240 (15%)

Query: 67   LSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGE 126
            +  +PG V  PR  R   GE+G     G  G  G    +G    P      V  PG+ G 
Sbjct: 1137 IQGEPG-VKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP----GPVGFPGDPGP 1191

Query: 127  CGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVP 186
             G     G+     DR G    PG+ G  G P  E G   PL +R    SPG +G  G  
Sbjct: 1192 PGEGGPRGQDGAKGDR-GEDGEPGQPGSPG-PTGENGPPGPLGKRGPAGSPGSEGRQGGK 1249

Query: 187  WREG--------GVWRPLERRGSVASPGEKGECGVPWREGRVWRP-LERRASVASP---- 233
              +G        G   P+   G    PG  G  G+P   G+  RP    +A    P    
Sbjct: 1250 GAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPP 1309

Query: 234  ---------GQKGECGVPWREGAVWRPLDRR--------GSVASPGEKGECGVRWREGRV 276
                     G KGE G P   G +  P ++         G   SPG+KGE G+    G +
Sbjct: 1310 GLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPI 1369



 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 63/201 (31%), Positives = 79/201 (39%), Gaps = 15/201 (7%)

Query: 81  RSIDGEAGHSEAAGEKGECGIPWTEG--QVWRPLERRASVASPGEKGECGVPWREGRVWR 138
           R + GE+G     G KG  GIP   G   +  P   + S+   GE G  G     G    
Sbjct: 514 RGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGL 573

Query: 139 PLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGVPWREGGVWRPL 196
           P   +G++   GEKG  G P   G  G   P         PG KG  G    +G +  P 
Sbjct: 574 P-GPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPG 632

Query: 197 ER--------RGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAV 248
            R        RG     GEKGE G P  +G +    + R  V  PG +GE G    +G  
Sbjct: 633 PRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGD-RGEVGVPGSRGEDGPEGPKGRT 691

Query: 249 WRPLDRRGSVASPGEKGECGV 269
             P    G     GEKG+ GV
Sbjct: 692 -GPTGDPGPPGLMGEKGKLGV 711



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 73/270 (27%), Positives = 97/270 (35%), Gaps = 38/270 (14%)

Query: 23  GALTIVSSHGGDSDKDLCARTQIYGAQPREDQMGSVEKLTTSAFLSAKPGSVPAPRPLRS 82
           G + +  S G D  +    RT   G       MG   KL         PG      P  S
Sbjct: 671 GEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGL----PGYPGRQGPKGS 726

Query: 83  IDGEAGHSEAAGEKGECGI-----PWTEGQVWRPLERRASVASPGEKGECGVPWREGRVW 137
           + G  G   A+GEKG  G+     P  E     P  +R    + G+ G  G    +G   
Sbjct: 727 L-GFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHG 785

Query: 138 RPLDR-----RGSVASPGEKGECGVPWREGGVWRPLER-----RASVASPGQKGECGVPW 187
            P +R     +G    PG KG  G P ++G    P +R     +     PG  G  G P 
Sbjct: 786 PPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVG-PQ 844

Query: 188 REGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGA 247
              G   P+  RG    PG  GE G+P   G+            + G  G  G P ++G 
Sbjct: 845 GAAGETGPMGERGHPGPPGPPGEQGLPGTAGK----------EGTKGDPGPPGAPGKDG- 893

Query: 248 VWRPLDRRGSVAS---PGEKGECGVRWREG 274
              P   RG       PG  G  G++  EG
Sbjct: 894 ---PAGLRGFPGERGLPGTAGGPGLKGNEG 920



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 60/220 (27%), Positives = 79/220 (35%), Gaps = 42/220 (19%)

Query: 85   GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
            G  GH  A G++G  G     G    P+  +      GEKGE G     G    P   RG
Sbjct: 1046 GPQGHFGAKGDEGTRGFNGPPG----PIGLQGLPGPSGEKGETGDVGPMGPPGPP-GPRG 1100

Query: 145  SVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG--GVWRPLERRGSV 202
                 G  G  G P   G +  P E+       G+ GE G P  +G  GV  P   RG  
Sbjct: 1101 PAGPNGADGPQGPPGGVGNLGPPGEK-------GEPGESGSPGIQGEPGVKGPRGERGEK 1153

Query: 203  ASPGEKGECGVPWREGRVWRPLER--------------------RASVASPGQKGECGVP 242
               G+ GE G P  +G       +                    R    + G +GE G P
Sbjct: 1154 GESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEP 1213

Query: 243  WREGAVW--------RPLDRRGSVASPGEKGECGVRWREG 274
             + G+           PL +RG   SPG +G  G +  +G
Sbjct: 1214 GQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKG 1253



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 56/192 (29%), Positives = 71/192 (36%), Gaps = 18/192 (9%)

Query: 85  GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
           GE G     GE G  G+P   G    P         PG  G  GV   +G    P   +G
Sbjct: 500 GEDGERGDDGEIGPRGLPGESG----PRGLLGPKGPPGIPGPPGVRGMDG----PQGPKG 551

Query: 145 SVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVAS 204
           S+   GE G  G     G    P  + A +   G+KG  G P   G         GS   
Sbjct: 552 SLGPQGEPGPPGQQGTPGTQGLPGPQGA-IGPHGEKGPQGKPGLPG-------MPGSDGP 603

Query: 205 PGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEK 264
           PG  G+ G P  +G    P   +  +  PG +G  GV    G        +G    PG K
Sbjct: 604 PGHPGKEGPPGTKGNQG-PSGPQGPLGYPGPRGVKGVDGIRGLKGHK-GEKGEDGFPGFK 661

Query: 265 GECGVRWREGRV 276
           G+ GV+   G V
Sbjct: 662 GDIGVKGDRGEV 673



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 59/210 (28%), Positives = 74/210 (35%), Gaps = 13/210 (6%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
           P     P+ L    G+AG    AG  G  G+P   G V            PGEKG  G  
Sbjct: 432 PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG-VKGDRGFDGLPGLPGEKGHRGDT 490

Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
             +G +  P    G     GE G  G+P   G    P         PG  G  GV   +G
Sbjct: 491 GAQG-LPGPPGEDGERGDDGEIGPRGLPGESG----PRGLLGPKGPPGIPGPPGVRGMDG 545

Query: 191 GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWR 250
               P   +GS+   GE G  G     G    P   + ++   G+KG  G P   G    
Sbjct: 546 ----PQGPKGSLGPQGEPGPPGQQGTPGTQGLP-GPQGAIGPHGEKGPQGKPGLPGMPGS 600

Query: 251 --PLDRRGSVASPGEKGECGVRWREGRVWY 278
             P    G    PG KG  G    +G + Y
Sbjct: 601 DGPPGHPGKEGPPGTKGNQGPSGPQGPLGY 630


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein
           [Homo sapiens]
          Length = 1629

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 68/214 (31%), Positives = 88/214 (41%), Gaps = 17/214 (7%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
           P   P PR ++ +DG  G     GEKGE G P  +G +    + R  V  PG +GE G  
Sbjct: 606 PLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGD-RGEVGVPGSRGEDGPE 664

Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGV--- 185
             +GR   P    G     GEKG+ GVP   G  G   P         PG  GE G    
Sbjct: 665 GPKGRT-GPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 723

Query: 186 -----PWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECG 240
                P  E G   P  +RG   + G+ G  G    +G    P ER      PG +G  G
Sbjct: 724 SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGER----GLPGPQGPNG 779

Query: 241 VPWREGAVWRPLDRRGSVASPGEKGECGVRWREG 274
            P  +G    P  + G    PG++GE G + + G
Sbjct: 780 FPGPKGPPGPP-GKDGLPGHPGQRGEVGFQGKTG 812



 Score = 69.3 bits (168), Expect = 4e-12
 Identities = 68/222 (30%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLER-----RASVASPGEKG 125
           P  +P P  +R +DG  G   + G +GE G P   GQ   P  +     + ++   GEKG
Sbjct: 510 PPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP---GQQGTPGTQGLPGPQGAIGPHGEKG 566

Query: 126 ECGVPWREGRVWR--PLDRRGSVASPGEKGECGVPWREGGVWRPLER--------RASVA 175
             G P   G      P    G    PG KG  G    +G +  P  R        R    
Sbjct: 567 PQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKG 626

Query: 176 SPGQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQ 235
             G+KGE G P  +G +    + RG V  PG +GE G    +GR   P          G+
Sbjct: 627 HKGEKGEDGFPGFKGDIGVKGD-RGEVGVPGSRGEDGPEGPKGRT-GPTGDPGPPGLMGE 684

Query: 236 KGECGVPWREGAVWR--PLDRRGSVASPGEKGECGVRWREGR 275
           KG+ GVP   G   R  P    G    PG  GE G R   G+
Sbjct: 685 KGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGK 726



 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 63/224 (28%), Positives = 84/224 (37%), Gaps = 48/224 (21%)

Query: 70   KPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGV 129
            +PG   +P P     GE G     G++G  G P +EG       R+    + G+ G  G 
Sbjct: 1191 EPGQPGSPGPT----GENGPPGPLGKRGPAGSPGSEG-------RQGGKGAKGDPGAIGA 1239

Query: 130  PWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWRE 189
            P + G    P+   G    PG  G  G+P   G   RP         PG  G  G+P   
Sbjct: 1240 PGKTG----PVGPAGPAGKPGPDGLRGLPGSVGQQGRP-GATGQAGPPGPVGPPGLPGLR 1294

Query: 190  GGVWRPLERR--------GSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGV 241
            G      E+         G     GEKG+ G+P  +G             SPGQKGE G+
Sbjct: 1295 GDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQG-------------SPGQKGEMGI 1341

Query: 242  PWREGAVW-----------RPLDRRGSVASPGEKGECGVRWREG 274
            P   G +             P   +G+    G KGE GV+   G
Sbjct: 1342 PGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPG 1385



 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 60/193 (31%), Positives = 76/193 (39%), Gaps = 30/193 (15%)

Query: 85  GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
           GE GH    G  GE G+P T G+            + G+ G  G P ++G    P   RG
Sbjct: 833 GERGHPGPPGPPGEQGLPGTAGK----------EGTKGDPGPPGAPGKDG----PAGLRG 878

Query: 145 SVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVAS 204
                G  G  G P  +G    P        SPG++G  G     GG   P  R G    
Sbjct: 879 FPGERGLPGTAGGPGLKGNE-GPSGPPGPAGSPGERGAAG----SGGPIGPPGRPGPQGP 933

Query: 205 PGEKGECGVPWREGRVWRPLER---RASVASPGQKGECGVPWREGAVWRPLDRRGSVASP 261
           PG  GE GVP  +G +  P  R   +  V  PG  G  GV   +G        +G V  P
Sbjct: 934 PGAAGEKGVPGEKGPI-GPTGRDGVQGPVGLPGPAGPPGVAGEDG-------DKGEVGDP 985

Query: 262 GEKGECGVRWREG 274
           G+KG  G +   G
Sbjct: 986 GQKGTKGNKGEHG 998



 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 69/240 (28%), Positives = 89/240 (37%), Gaps = 37/240 (15%)

Query: 67   LSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGE 126
            +  +PG V  PR  R   GE+G     G  G  G    +G    P      V  PG+ G 
Sbjct: 1116 IQGEPG-VKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP----GPVGFPGDPGP 1170

Query: 127  CGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVP 186
             G     G+     DR G    PG+ G  G P  E G   PL +R    SPG +G  G  
Sbjct: 1171 PGEGGPRGQDGAKGDR-GEDGEPGQPGSPG-PTGENGPPGPLGKRGPAGSPGSEGRQGGK 1228

Query: 187  WREG--------GVWRPLERRGSVASPGEKGECGVPWREGRVWRP-LERRASVASP---- 233
              +G        G   P+   G    PG  G  G+P   G+  RP    +A    P    
Sbjct: 1229 GAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPP 1288

Query: 234  ---------GQKGECGVPWREGAVWRPLDRR--------GSVASPGEKGECGVRWREGRV 276
                     G KGE G P   G +  P ++         G   SPG+KGE G+    G +
Sbjct: 1289 GLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPI 1348



 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 63/201 (31%), Positives = 79/201 (39%), Gaps = 15/201 (7%)

Query: 81  RSIDGEAGHSEAAGEKGECGIPWTEG--QVWRPLERRASVASPGEKGECGVPWREGRVWR 138
           R + GE+G     G KG  GIP   G   +  P   + S+   GE G  G     G    
Sbjct: 493 RGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGL 552

Query: 139 PLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGVPWREGGVWRPL 196
           P   +G++   GEKG  G P   G  G   P         PG KG  G    +G +  P 
Sbjct: 553 P-GPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPG 611

Query: 197 ER--------RGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAV 248
            R        RG     GEKGE G P  +G +    + R  V  PG +GE G    +G  
Sbjct: 612 PRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGD-RGEVGVPGSRGEDGPEGPKGRT 670

Query: 249 WRPLDRRGSVASPGEKGECGV 269
             P    G     GEKG+ GV
Sbjct: 671 -GPTGDPGPPGLMGEKGKLGV 690



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 73/270 (27%), Positives = 97/270 (35%), Gaps = 38/270 (14%)

Query: 23  GALTIVSSHGGDSDKDLCARTQIYGAQPREDQMGSVEKLTTSAFLSAKPGSVPAPRPLRS 82
           G + +  S G D  +    RT   G       MG   KL         PG      P  S
Sbjct: 650 GEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGL----PGYPGRQGPKGS 705

Query: 83  IDGEAGHSEAAGEKGECGI-----PWTEGQVWRPLERRASVASPGEKGECGVPWREGRVW 137
           + G  G   A+GEKG  G+     P  E     P  +R    + G+ G  G    +G   
Sbjct: 706 L-GFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHG 764

Query: 138 RPLDR-----RGSVASPGEKGECGVPWREGGVWRPLER-----RASVASPGQKGECGVPW 187
            P +R     +G    PG KG  G P ++G    P +R     +     PG  G  G P 
Sbjct: 765 PPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVG-PQ 823

Query: 188 REGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGA 247
              G   P+  RG    PG  GE G+P   G+            + G  G  G P ++G 
Sbjct: 824 GAAGETGPMGERGHPGPPGPPGEQGLPGTAGK----------EGTKGDPGPPGAPGKDG- 872

Query: 248 VWRPLDRRGSVAS---PGEKGECGVRWREG 274
              P   RG       PG  G  G++  EG
Sbjct: 873 ---PAGLRGFPGERGLPGTAGGPGLKGNEG 899



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 60/220 (27%), Positives = 79/220 (35%), Gaps = 42/220 (19%)

Query: 85   GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
            G  GH  A G++G  G     G    P+  +      GEKGE G     G    P   RG
Sbjct: 1025 GPQGHFGAKGDEGTRGFNGPPG----PIGLQGLPGPSGEKGETGDVGPMGPPGPP-GPRG 1079

Query: 145  SVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG--GVWRPLERRGSV 202
                 G  G  G P   G +  P E+       G+ GE G P  +G  GV  P   RG  
Sbjct: 1080 PAGPNGADGPQGPPGGVGNLGPPGEK-------GEPGESGSPGIQGEPGVKGPRGERGEK 1132

Query: 203  ASPGEKGECGVPWREGRVWRPLER--------------------RASVASPGQKGECGVP 242
               G+ GE G P  +G       +                    R    + G +GE G P
Sbjct: 1133 GESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEP 1192

Query: 243  WREGAVW--------RPLDRRGSVASPGEKGECGVRWREG 274
             + G+           PL +RG   SPG +G  G +  +G
Sbjct: 1193 GQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKG 1232



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 56/192 (29%), Positives = 71/192 (36%), Gaps = 18/192 (9%)

Query: 85  GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
           GE G     GE G  G+P   G    P         PG  G  GV   +G    P   +G
Sbjct: 479 GEDGERGDDGEIGPRGLPGESG----PRGLLGPKGPPGIPGPPGVRGMDG----PQGPKG 530

Query: 145 SVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVAS 204
           S+   GE G  G     G    P  + A +   G+KG  G P   G         GS   
Sbjct: 531 SLGPQGEPGPPGQQGTPGTQGLPGPQGA-IGPHGEKGPQGKPGLPG-------MPGSDGP 582

Query: 205 PGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEK 264
           PG  G+ G P  +G    P   +  +  PG +G  GV    G        +G    PG K
Sbjct: 583 PGHPGKEGPPGTKGNQG-PSGPQGPLGYPGPRGVKGVDGIRGLKGHK-GEKGEDGFPGFK 640

Query: 265 GECGVRWREGRV 276
           G+ GV+   G V
Sbjct: 641 GDIGVKGDRGEV 652



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 59/210 (28%), Positives = 74/210 (35%), Gaps = 13/210 (6%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
           P     P+ L    G+AG    AG  G  G+P   G V            PGEKG  G  
Sbjct: 411 PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG-VKGDRGFDGLPGLPGEKGHRGDT 469

Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
             +G +  P    G     GE G  G+P   G    P         PG  G  GV   +G
Sbjct: 470 GAQG-LPGPPGEDGERGDDGEIGPRGLPGESG----PRGLLGPKGPPGIPGPPGVRGMDG 524

Query: 191 GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWR 250
               P   +GS+   GE G  G     G    P   + ++   G+KG  G P   G    
Sbjct: 525 ----PQGPKGSLGPQGEPGPPGQQGTPGTQGLP-GPQGAIGPHGEKGPQGKPGLPGMPGS 579

Query: 251 --PLDRRGSVASPGEKGECGVRWREGRVWY 278
             P    G    PG KG  G    +G + Y
Sbjct: 580 DGPPGHPGKEGPPGTKGNQGPSGPQGPLGY 609


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein
           [Homo sapiens]
          Length = 1736

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 68/214 (31%), Positives = 88/214 (41%), Gaps = 17/214 (7%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
           P   P PR ++ +DG  G     GEKGE G P  +G +    + R  V  PG +GE G  
Sbjct: 713 PLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGD-RGEVGVPGSRGEDGPE 771

Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGV--- 185
             +GR   P    G     GEKG+ GVP   G  G   P         PG  GE G    
Sbjct: 772 GPKGRT-GPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 830

Query: 186 -----PWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECG 240
                P  E G   P  +RG   + G+ G  G    +G    P ER      PG +G  G
Sbjct: 831 SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGER----GLPGPQGPNG 886

Query: 241 VPWREGAVWRPLDRRGSVASPGEKGECGVRWREG 274
            P  +G    P  + G    PG++GE G + + G
Sbjct: 887 FPGPKGPPGPP-GKDGLPGHPGQRGEVGFQGKTG 919



 Score = 69.3 bits (168), Expect = 4e-12
 Identities = 68/222 (30%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLER-----RASVASPGEKG 125
           P  +P P  +R +DG  G   + G +GE G P   GQ   P  +     + ++   GEKG
Sbjct: 617 PPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP---GQQGTPGTQGLPGPQGAIGPHGEKG 673

Query: 126 ECGVPWREGRVWR--PLDRRGSVASPGEKGECGVPWREGGVWRPLER--------RASVA 175
             G P   G      P    G    PG KG  G    +G +  P  R        R    
Sbjct: 674 PQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKG 733

Query: 176 SPGQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQ 235
             G+KGE G P  +G +    + RG V  PG +GE G    +GR   P          G+
Sbjct: 734 HKGEKGEDGFPGFKGDIGVKGD-RGEVGVPGSRGEDGPEGPKGRT-GPTGDPGPPGLMGE 791

Query: 236 KGECGVPWREGAVWR--PLDRRGSVASPGEKGECGVRWREGR 275
           KG+ GVP   G   R  P    G    PG  GE G R   G+
Sbjct: 792 KGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGK 833



 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 63/224 (28%), Positives = 84/224 (37%), Gaps = 48/224 (21%)

Query: 70   KPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGV 129
            +PG   +P P     GE G     G++G  G P +EG       R+    + G+ G  G 
Sbjct: 1298 EPGQPGSPGPT----GENGPPGPLGKRGPAGSPGSEG-------RQGGKGAKGDPGAIGA 1346

Query: 130  PWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWRE 189
            P + G    P+   G    PG  G  G+P   G   RP         PG  G  G+P   
Sbjct: 1347 PGKTG----PVGPAGPAGKPGPDGLRGLPGSVGQQGRP-GATGQAGPPGPVGPPGLPGLR 1401

Query: 190  GGVWRPLERR--------GSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGV 241
            G      E+         G     GEKG+ G+P  +G             SPGQKGE G+
Sbjct: 1402 GDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQG-------------SPGQKGEMGI 1448

Query: 242  PWREGAVW-----------RPLDRRGSVASPGEKGECGVRWREG 274
            P   G +             P   +G+    G KGE GV+   G
Sbjct: 1449 PGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPG 1492



 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 60/193 (31%), Positives = 76/193 (39%), Gaps = 30/193 (15%)

Query: 85   GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
            GE GH    G  GE G+P T G+            + G+ G  G P ++G    P   RG
Sbjct: 940  GERGHPGPPGPPGEQGLPGTAGK----------EGTKGDPGPPGAPGKDG----PAGLRG 985

Query: 145  SVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVAS 204
                 G  G  G P  +G    P        SPG++G  G     GG   P  R G    
Sbjct: 986  FPGERGLPGTAGGPGLKGNE-GPSGPPGPAGSPGERGAAG----SGGPIGPPGRPGPQGP 1040

Query: 205  PGEKGECGVPWREGRVWRPLER---RASVASPGQKGECGVPWREGAVWRPLDRRGSVASP 261
            PG  GE GVP  +G +  P  R   +  V  PG  G  GV   +G        +G V  P
Sbjct: 1041 PGAAGEKGVPGEKGPI-GPTGRDGVQGPVGLPGPAGPPGVAGEDG-------DKGEVGDP 1092

Query: 262  GEKGECGVRWREG 274
            G+KG  G +   G
Sbjct: 1093 GQKGTKGNKGEHG 1105



 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 69/240 (28%), Positives = 89/240 (37%), Gaps = 37/240 (15%)

Query: 67   LSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGE 126
            +  +PG V  PR  R   GE+G     G  G  G    +G    P      V  PG+ G 
Sbjct: 1223 IQGEPG-VKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP----GPVGFPGDPGP 1277

Query: 127  CGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVP 186
             G     G+     DR G    PG+ G  G P  E G   PL +R    SPG +G  G  
Sbjct: 1278 PGEGGPRGQDGAKGDR-GEDGEPGQPGSPG-PTGENGPPGPLGKRGPAGSPGSEGRQGGK 1335

Query: 187  WREG--------GVWRPLERRGSVASPGEKGECGVPWREGRVWRP-LERRASVASP---- 233
              +G        G   P+   G    PG  G  G+P   G+  RP    +A    P    
Sbjct: 1336 GAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPP 1395

Query: 234  ---------GQKGECGVPWREGAVWRPLDRR--------GSVASPGEKGECGVRWREGRV 276
                     G KGE G P   G +  P ++         G   SPG+KGE G+    G +
Sbjct: 1396 GLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPI 1455



 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 63/201 (31%), Positives = 79/201 (39%), Gaps = 15/201 (7%)

Query: 81  RSIDGEAGHSEAAGEKGECGIPWTEG--QVWRPLERRASVASPGEKGECGVPWREGRVWR 138
           R + GE+G     G KG  GIP   G   +  P   + S+   GE G  G     G    
Sbjct: 600 RGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGL 659

Query: 139 PLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGVPWREGGVWRPL 196
           P   +G++   GEKG  G P   G  G   P         PG KG  G    +G +  P 
Sbjct: 660 P-GPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPG 718

Query: 197 ER--------RGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAV 248
            R        RG     GEKGE G P  +G +    + R  V  PG +GE G    +G  
Sbjct: 719 PRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGD-RGEVGVPGSRGEDGPEGPKGRT 777

Query: 249 WRPLDRRGSVASPGEKGECGV 269
             P    G     GEKG+ GV
Sbjct: 778 -GPTGDPGPPGLMGEKGKLGV 797



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 73/270 (27%), Positives = 97/270 (35%), Gaps = 38/270 (14%)

Query: 23   GALTIVSSHGGDSDKDLCARTQIYGAQPREDQMGSVEKLTTSAFLSAKPGSVPAPRPLRS 82
            G + +  S G D  +    RT   G       MG   KL         PG      P  S
Sbjct: 757  GEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGL----PGYPGRQGPKGS 812

Query: 83   IDGEAGHSEAAGEKGECGI-----PWTEGQVWRPLERRASVASPGEKGECGVPWREGRVW 137
            + G  G   A+GEKG  G+     P  E     P  +R    + G+ G  G    +G   
Sbjct: 813  L-GFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHG 871

Query: 138  RPLDR-----RGSVASPGEKGECGVPWREGGVWRPLER-----RASVASPGQKGECGVPW 187
             P +R     +G    PG KG  G P ++G    P +R     +     PG  G  G P 
Sbjct: 872  PPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVG-PQ 930

Query: 188  REGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGA 247
               G   P+  RG    PG  GE G+P   G+            + G  G  G P ++G 
Sbjct: 931  GAAGETGPMGERGHPGPPGPPGEQGLPGTAGK----------EGTKGDPGPPGAPGKDG- 979

Query: 248  VWRPLDRRGSVAS---PGEKGECGVRWREG 274
               P   RG       PG  G  G++  EG
Sbjct: 980  ---PAGLRGFPGERGLPGTAGGPGLKGNEG 1006



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 60/220 (27%), Positives = 79/220 (35%), Gaps = 42/220 (19%)

Query: 85   GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
            G  GH  A G++G  G     G    P+  +      GEKGE G     G    P   RG
Sbjct: 1132 GPQGHFGAKGDEGTRGFNGPPG----PIGLQGLPGPSGEKGETGDVGPMGPPGPP-GPRG 1186

Query: 145  SVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG--GVWRPLERRGSV 202
                 G  G  G P   G +  P E+       G+ GE G P  +G  GV  P   RG  
Sbjct: 1187 PAGPNGADGPQGPPGGVGNLGPPGEK-------GEPGESGSPGIQGEPGVKGPRGERGEK 1239

Query: 203  ASPGEKGECGVPWREGRVWRPLER--------------------RASVASPGQKGECGVP 242
               G+ GE G P  +G       +                    R    + G +GE G P
Sbjct: 1240 GESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEP 1299

Query: 243  WREGAVW--------RPLDRRGSVASPGEKGECGVRWREG 274
             + G+           PL +RG   SPG +G  G +  +G
Sbjct: 1300 GQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKG 1339



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 56/192 (29%), Positives = 71/192 (36%), Gaps = 18/192 (9%)

Query: 85  GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
           GE G     GE G  G+P   G    P         PG  G  GV   +G    P   +G
Sbjct: 586 GEDGERGDDGEIGPRGLPGESG----PRGLLGPKGPPGIPGPPGVRGMDG----PQGPKG 637

Query: 145 SVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVAS 204
           S+   GE G  G     G    P  + A +   G+KG  G P   G         GS   
Sbjct: 638 SLGPQGEPGPPGQQGTPGTQGLPGPQGA-IGPHGEKGPQGKPGLPG-------MPGSDGP 689

Query: 205 PGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEK 264
           PG  G+ G P  +G    P   +  +  PG +G  GV    G        +G    PG K
Sbjct: 690 PGHPGKEGPPGTKGNQG-PSGPQGPLGYPGPRGVKGVDGIRGLKGHK-GEKGEDGFPGFK 747

Query: 265 GECGVRWREGRV 276
           G+ GV+   G V
Sbjct: 748 GDIGVKGDRGEV 759



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 59/210 (28%), Positives = 74/210 (35%), Gaps = 13/210 (6%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
           P     P+ L    G+AG    AG  G  G+P   G V            PGEKG  G  
Sbjct: 518 PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG-VKGDRGFDGLPGLPGEKGHRGDT 576

Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
             +G +  P    G     GE G  G+P   G    P         PG  G  GV   +G
Sbjct: 577 GAQG-LPGPPGEDGERGDDGEIGPRGLPGESG----PRGLLGPKGPPGIPGPPGVRGMDG 631

Query: 191 GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWR 250
               P   +GS+   GE G  G     G    P   + ++   G+KG  G P   G    
Sbjct: 632 ----PQGPKGSLGPQGEPGPPGQQGTPGTQGLP-GPQGAIGPHGEKGPQGKPGLPGMPGS 686

Query: 251 --PLDRRGSVASPGEKGECGVRWREGRVWY 278
             P    G    PG KG  G    +G + Y
Sbjct: 687 DGPPGHPGKEGPPGTKGNQGPSGPQGPLGY 716


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 64/205 (31%), Positives = 82/205 (40%), Gaps = 46/205 (22%)

Query: 75  PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
           P P+ L+ + G  G     GE G+ G P  +G    P        +PG KG+ G P   G
Sbjct: 635 PGPQGLQGLPGTGG---PPGENGKPGEPGPKGDAGAP-------GAPGGKGDAGAPGERG 684

Query: 135 RVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWR 194
                    G   +PG +G  G P  EGG       + +   PG  G  G P  +G    
Sbjct: 685 PP-------GLAGAPGLRGGAGPPGPEGG-------KGAAGPPGPPGAAGTPGLQG---M 727

Query: 195 PLERRGSVASPGEKGE---------CGVPWREG--RVWRPLERRASVASPGQKGECGVPW 243
           P E RG + SPG KG+          GVP ++G      P+        PG KGE G P 
Sbjct: 728 PGE-RGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPG 786

Query: 244 REGAVWRPLDRRGSVASPGEKGECG 268
             G         G   SPGE+GE G
Sbjct: 787 LPGIA-------GPRGSPGERGETG 804



 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 65/217 (29%), Positives = 81/217 (37%), Gaps = 28/217 (12%)

Query: 69  AKPGSVPA---PRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKG 125
           A P  +P    P   R   G AG   AAGE G  G+P   G    P     S   PG  G
Sbjct: 494 AGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMP----GSPGGPGSDG 549

Query: 126 ECGVPWREGRVWR--------PLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASP 177
           + G P  +G   R        P  + G +  PG KG  G P + G    P         P
Sbjct: 550 KPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGP-GGPGPQGPP 608

Query: 178 GQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKG 237
           G+ GE G P    G   P   +G    PG +G  G+P   G    P         PG KG
Sbjct: 609 GKNGETG-PQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGG----PPGENGKPGEPGPKG 663

Query: 238 ECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREG 274
           + G P   G        +G   +PGE+G  G+    G
Sbjct: 664 DAGAPGAPGG-------KGDAGAPGERGPPGLAGAPG 693



 Score = 72.0 bits (175), Expect = 6e-13
 Identities = 70/223 (31%), Positives = 87/223 (39%), Gaps = 20/223 (8%)

Query: 71  PGSVPAPRPLRSIDGEAGH---SEAAGEKGECGIPWTEGQVWRPLERRA-----SVASPG 122
           P  +  P  +    G  GH       GEKGE G P  +G+   P E  A        +PG
Sbjct: 247 PPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPG 306

Query: 123 EKGECGVPWREGRVWRPLDR--RGSVASPGEKGECGVPWREG--GVWRPLERRASVASPG 178
           E+G  G+P   G       R   G    PG  G  G P   G  G   P     S  +PG
Sbjct: 307 ERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPG 366

Query: 179 QKGECGVPWREGGVWRPLERRGSVASPGEKGE---CGVPWREGRVWR--PLERRASVASP 233
           Q+GE G P    G   P    G   SPG KGE    G+P   G +    P     +  +P
Sbjct: 367 QRGEPG-PQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAP 425

Query: 234 GQKGECGVPWREGAVWRPLDR--RGSVASPGEKGECGVRWREG 274
           G +G  G P + GA   P  R  RG    PG  G  G   ++G
Sbjct: 426 GLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDG 468



 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 63/202 (31%), Positives = 75/202 (37%), Gaps = 22/202 (10%)

Query: 75  PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
           P P   +   G  G   AAG  G  G+P   G +  P   +     PG  G  GVP ++G
Sbjct: 701 PGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSP-GPKGDKGEPGGPGADGVPGKDG 759

Query: 135 R--VWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGV 192
                 P+   G    PG+KGE G P   G             SPG++GE G P   G  
Sbjct: 760 PRGPTGPIGPPGPAGQPGDKGEGGAPGLPG-------IAGPRGSPGERGETGPPGPAGFP 812

Query: 193 WRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPL 252
             P    G    PG KGE G P  +G    P         PG  G  G P  +G      
Sbjct: 813 GAP----GQNGEPGGKGERGAPGEKGEGGPP----GVAGPPGGSGPAGPPGPQGV----K 860

Query: 253 DRRGSVASPGEKGECGVRWREG 274
             RGS   PG  G  G R   G
Sbjct: 861 GERGSPGGPGAAGFPGARGLPG 882



 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 67/203 (33%), Positives = 84/203 (41%), Gaps = 26/203 (12%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
           PG++    P    DGE+G     GE+G  G P  +G    P         PG KG  G  
Sbjct: 218 PGAIGPSGPAGK-DGESGRPGRPGERGLPGPPGIKGPAGIP-------GFPGMKGHRGFD 269

Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
            R G        +G   +PG KGE G+P  E G   P+  R    +PG++G  G+P   G
Sbjct: 270 GRNG-------EKGETGAPGLKGENGLP-GENGAPGPMGPR---GAPGERGRPGLPGAAG 318

Query: 191 -----GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWRE 245
                G      + G    PG  G  G P  +G V  P     S  +PGQ+GE G     
Sbjct: 319 ARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEV-GPAGSPGSNGAPGQRGEPGPQGHA 377

Query: 246 GAVWRPLDRRGSVASPGEKGECG 268
           GA   P    G   SPG KGE G
Sbjct: 378 GAQGPP-GPPGINGSPGGKGEMG 399



 Score = 65.9 bits (159), Expect = 4e-11
 Identities = 66/219 (30%), Positives = 84/219 (38%), Gaps = 31/219 (14%)

Query: 82  SIDGEAGHSEAAGEKGECGIPWTEGQVWRPLE--RRASVASPGEKGECGVP--------- 130
           ++ G AG+   AG  G  G P T G    P     +     PG+ G  G P         
Sbjct: 165 AVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPS 224

Query: 131 ------WREGRVWRPLDRRGSVASPGEKGECGVPWREG-----GVWRPLERRASVASPGQ 179
                    GR  RP   RG    PG KG  G+P   G     G       +    +PG 
Sbjct: 225 GPAGKDGESGRPGRP-GERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGL 283

Query: 180 KGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRA--SVASPGQKG 237
           KGE G+P  E G   P+  RG   +PGE+G  G+P   G       R +      PG  G
Sbjct: 284 KGENGLP-GENGAPGPMGPRG---APGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPG 339

Query: 238 ECGVPWREGAVWR--PLDRRGSVASPGEKGECGVRWREG 274
             G P   GA     P    GS  +PG++GE G +   G
Sbjct: 340 TAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAG 378



 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 63/215 (29%), Positives = 78/215 (36%), Gaps = 25/215 (11%)

Query: 75  PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRP--LERRASVASPGEKGECGVPWR 132
           P PR  R   G  G   A GE G+ G P   G    P     R +    G  G  G+P  
Sbjct: 443 PGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGE 502

Query: 133 EGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGV 192
           +G    P   RG+    G +G  G P R+G              PG +G  G P   G  
Sbjct: 503 KG----PAGERGAPGPAGPRGAAGEPGRDG----------VPGGPGMRGMPGSPGGPGSD 548

Query: 193 WRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPL 252
            +P    G   S GE G  G P   G    P  +   +  PG KG  G P + G    P 
Sbjct: 549 GKP----GPPGSQGESGRPGPPGPSG----PRGQPGVMGFPGPKGNDGAPGKNGERGGP- 599

Query: 253 DRRGSVASPGEKGECGVRWREGRVWYSLDKRGSVP 287
              G    PG+ GE G +   G      DK  + P
Sbjct: 600 GGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGP 634



 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 64/234 (27%), Positives = 83/234 (35%), Gaps = 37/234 (15%)

Query: 68   SAKPGS--------VPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVA 119
            S KPG+         P P+ L  + G AG     G  G  G+P  +G      +R  +  
Sbjct: 980  SGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGEN-G 1038

Query: 120  SPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASP 177
            SPG  G  G P   G V  P  + G     G  G  G P   G  G   P   R      
Sbjct: 1039 SPGAPGAPGHPGPPGPVG-PAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGET 1097

Query: 178  GQKGECGVPWREG--------GVWRPLERRGSVASPGEKGE------CGVPWREGRVWRP 223
            G++G  G+    G        G   P  ++G++ SPG  G        G P ++G    P
Sbjct: 1098 GERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHP 1157

Query: 224  -----------LERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGE 266
                          R S  SPG  G+ G P   GA        G+ A  G  GE
Sbjct: 1158 GPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGE 1211



 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 74/255 (29%), Positives = 93/255 (36%), Gaps = 35/255 (13%)

Query: 71   PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
            P   P P+ ++   G  G   AAG  G  G+P   G          S  +PG  G  G P
Sbjct: 850  PAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPG----------SNGNPGPPGPSGSP 899

Query: 131  WREGRVWRPLDRRGSVASP---GEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPW 187
             ++G    P    G+  SP   G KG+ G P  +G        +    +PG  G  G+  
Sbjct: 900  GKDGPP-GPAGNTGAPGSPGVSGPKGDAGQPGEKGSP----GAQGPPGAPGPLGIAGITG 954

Query: 188  REGGVWRP--LERRGSVASPGEKGECGVPWREGRVW-------RPLERRASVAS----PG 234
              G    P     RGS    G KGE G P   G          + L   A  A      G
Sbjct: 955  ARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDG 1014

Query: 235  QKGECGVPWREGAVWRPLDR--RGSVASPGEKGECGVRWREGRVWYSLDKRGSVPA--AL 290
              G  G+P R+G+     DR   GS  +PG  G  G     G    S D+  S PA  A 
Sbjct: 1015 NPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAG 1074

Query: 291  ASQRHALLALPQPQG 305
            A         P PQG
Sbjct: 1075 APGPAGSRGAPGPQG 1089



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 65/232 (28%), Positives = 85/232 (36%), Gaps = 33/232 (14%)

Query: 68   SAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVA-----SPG 122
            +  PG  P P      DG  G +   G  G  G+   +G   +P E+ +  A     +PG
Sbjct: 887  NGNPGP-PGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPG 945

Query: 123  EKGECGVPWREGRVWRP--LDRRGSVASPGEKGECGVPWREG--GVWRP-----LERRAS 173
              G  G+    G    P     RGS    G KGE G P   G  G   P     L   A 
Sbjct: 946  PLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAG 1005

Query: 174  VASP----GQKGECGVPWREGGVWRPLER--RGSVASPGEKGECGVPWREGRVWRPLERR 227
             A      G  G  G+P R+G      +R   GS  +PG  G  G P   G   +  +R 
Sbjct: 1006 TAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRG 1065

Query: 228  AS-----VASPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREG 274
             S       +PG  G  G P  +G        RG     GE+G  G++   G
Sbjct: 1066 ESGPAGPAGAPGPAGSRGAPGPQGP-------RGDKGETGERGAAGIKGHRG 1110



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 42/148 (28%), Positives = 55/148 (37%), Gaps = 16/148 (10%)

Query: 138 RPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGV----PWREGGVW 193
           RP + +G     G+ G  G+P R G    P  +  S  SPG  G C      P      +
Sbjct: 97  RPPNGQGPQGPKGDPGPPGIPGRNGDPGIP-GQPGSPGSPGPPGICESCPTGPQNYSPQY 155

Query: 194 RPLERRGSVA------SPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGA 247
              + +  VA       PG  G  G P   G    P     S  SPG +G  G P + G 
Sbjct: 156 DSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHP----GSPGSPGYQGPPGEPGQAGP 211

Query: 248 VWRPLDRRGSVASPGEKGECGVRWREGR 275
              P    G++   G  G+ G   R GR
Sbjct: 212 SGPP-GPPGAIGPSGPAGKDGESGRPGR 238


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 67/211 (31%), Positives = 88/211 (41%), Gaps = 24/211 (11%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
           PG V  PR  R   GE G   A G +G  G+P T G    P         PG +G  G+ 
Sbjct: 692 PGLV-GPRGERGFPGERGSPGAQGLQGPRGLPGTPG-TDGPKGASGPAGPPGAQGPPGLQ 749

Query: 131 WREGR-----VWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGEC 183
              G      +  P   RG V   GEKG  G P ++G  G+  P+       + G+KGE 
Sbjct: 750 GMPGERGAAGIAGPKGDRGDV---GEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEV 806

Query: 184 GVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPW 243
           G P   G         G+  +PGE+GE G P   G    P     +   PG KGE G   
Sbjct: 807 GPPGPAGSA-------GARGAPGERGETGPPGPAGFAGPP----GADGQPGAKGEQGEAG 855

Query: 244 REGAVWRPLDRRGSVASPGEKGECGVRWREG 274
           ++G    P   +G   +PG +G  GV   +G
Sbjct: 856 QKGDAGAP-GPQGPSGAPGPQGPTGVTGPKG 885



 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 64/216 (29%), Positives = 82/216 (37%), Gaps = 39/216 (18%)

Query: 71   PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
            P   P P+    + G  G   A G  G  G P   G+V  P     S  +PG  G  G  
Sbjct: 868  PSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP----GSNGNPGPPGPPGPS 923

Query: 131  WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
             ++G    P   RG    PG  GE G+             +     PG+KGE G     G
Sbjct: 924  GKDG----PKGARGDSGPPGRAGEPGL-------------QGPAGPPGEKGEPGDDGPSG 966

Query: 191  GVWRP-----LERRGSVASPGEKGECGVPWREGRVWRPLERRASVAS-----------PG 234
                P       +RG V  PG++GE G P   G    P ++ A  AS           PG
Sbjct: 967  AEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPG 1026

Query: 235  QKGECGVPWREGAVWR--PLDRRGSVASPGEKGECG 268
              G  G P REG+     P  R G+    G++GE G
Sbjct: 1027 LTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETG 1062



 Score = 69.3 bits (168), Expect = 4e-12
 Identities = 61/201 (30%), Positives = 75/201 (37%), Gaps = 29/201 (14%)

Query: 75  PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
           P    L  + G  G+    G KGE G P  +G+   P E      SPG  G  G+P   G
Sbjct: 278 PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN----GSPGPMGPRGLPGERG 333

Query: 135 RVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG--GV 192
           R   P    G+  + G+ G  G P   G    P        +PG KGE G     G  G 
Sbjct: 334 RT-GPAGAAGARGNDGQPGPAGPPGPVGPAGGP----GFPGAPGAKGEAGPTGARGPEGA 388

Query: 193 WRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPL 252
             P    G+  SPG  G  G P  +G              PG KG  G P   GA   P 
Sbjct: 389 QGPRGEPGTPGSPGPAGASGNPGTDG-------------IPGAKGSAGAPGIAGAPGFPG 435

Query: 253 DR-----RGSVASPGEKGECG 268
            R     +G+    G KG+ G
Sbjct: 436 PRGPPGPQGATGPLGPKGQTG 456



 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 59/201 (29%), Positives = 81/201 (40%), Gaps = 32/201 (15%)

Query: 81  RSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPL 140
           + + GEAG     G +GE G P   G          +    G +G  G P  +G    P 
Sbjct: 683 QGVPGEAGAPGLVGPRGERGFPGERGS-------PGAQGLQGPRGLPGTPGTDG----PK 731

Query: 141 DRRGSVASPGEKGECGVPWREG-----GVWRPLERRASVASPGQKGECGVPWREG--GVW 193
              G    PG +G  G+    G     G+  P   R  V   G+KG  G P ++G  G+ 
Sbjct: 732 GASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV---GEKGPEGAPGKDGGRGLT 788

Query: 194 RPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLD 253
            P+   G   + GEKGE G P        P     +  +PG++GE G P   G    P  
Sbjct: 789 GPIGPPGPAGANGEKGEVGPP-------GPAGSAGARGAPGERGETGPPGPAGFAGPP-- 839

Query: 254 RRGSVASPGEKGECGVRWREG 274
             G+   PG KGE G   ++G
Sbjct: 840 --GADGQPGAKGEQGEAGQKG 858



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 61/200 (30%), Positives = 71/200 (35%), Gaps = 34/200 (17%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
           P   P P      DGEAG    AGE+G  G     G    P         PG KG  G P
Sbjct: 241 PRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTP-------GLPGVKGHRGYP 293

Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
             +G        +G   +PG KGE G P   G             SPG  G  G+P  E 
Sbjct: 294 GLDG-------AKGEAGAPGVKGESGSPGENG-------------SPGPMGPRGLP-GER 332

Query: 191 GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREG--AV 248
           G   P    G+  + G+ G  G P   G    P        +PG KGE G     G    
Sbjct: 333 GRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGP----GFPGAPGAKGEAGPTGARGPEGA 388

Query: 249 WRPLDRRGSVASPGEKGECG 268
             P    G+  SPG  G  G
Sbjct: 389 QGPRGEPGTPGSPGPAGASG 408



 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 63/231 (27%), Positives = 88/231 (38%), Gaps = 32/231 (13%)

Query: 70  KPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLER-----RASVASPGEK 124
           +PG+  +P P  +  G  G     G KG  G P   G    P  R     + +    G K
Sbjct: 394 EPGTPGSPGPAGA-SGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPK 452

Query: 125 GECGVPWREGRVWR--------PLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVAS 176
           G+ G P   G            P   +G+    GE+G+ G     GGV  P+       +
Sbjct: 453 GQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVG-PIGPPGERGA 511

Query: 177 PGQKGECGVPWREGGVWRPLER--------RGSVASPGEKGECGVPWREGRVWRPLE--- 225
           PG +G  G     G    P ER        +G+   PG  GE G+P   G   RP +   
Sbjct: 512 PGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGP 571

Query: 226 --RRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREG 274
             +     +PG+ G  G P  +GA  +P    G +  PG KG  G   + G
Sbjct: 572 QGKVGPSGAPGEDGRPGPPGPQGARGQP----GVMGFPGPKGANGEPGKAG 618



 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 62/234 (26%), Positives = 86/234 (36%), Gaps = 50/234 (21%)

Query: 75  PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWR--------PLERRASVASPGEKGE 126
           P P+      G+AG     G  G  G+P  +G+           P   R    +PG  G 
Sbjct: 605 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 664

Query: 127 CGV---PWREGRVWRPLDR--------------RGSVASPGEKGECGVPWREG------- 162
            G+   P   G   +P D+              RG    PGE+G  G    +G       
Sbjct: 665 QGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGT 724

Query: 163 -GVWRPLERRASVASPGQKGECGVPWREG-----GVWRPLERRGSVASPGEKGECGVPWR 216
            G   P         PG +G  G+    G     G+  P   RG V   GEKG  G P +
Sbjct: 725 PGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV---GEKGPEGAPGK 781

Query: 217 EG--RVWRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECG 268
           +G   +  P+       + G+KGE G P   G+        G+  +PGE+GE G
Sbjct: 782 DGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSA-------GARGAPGERGETG 828



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 59/208 (28%), Positives = 70/208 (33%), Gaps = 32/208 (15%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
           P     PR  R   GE G     G  GE G P   G              PG  G  G P
Sbjct: 127 PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPG-------------PPGPPGPPGPP 173

Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
              G         G         + GV     G   P        +PG +G  G P   G
Sbjct: 174 GLGGNF--AAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG 231

Query: 191 --GVWRPLERR---GSVASPGEKGECGVPWREGRVWRPLERRA-----SVASPGQKGECG 240
             GV  P+  R   G    PG+ GE G P + G    P  + A     +   PG KG  G
Sbjct: 232 EPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRG 291

Query: 241 VPWREGAVWRPLDRRGSVASPGEKGECG 268
            P  +GA       +G   +PG KGE G
Sbjct: 292 YPGLDGA-------KGEAGAPGVKGESG 312



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 53/208 (25%), Positives = 66/208 (31%), Gaps = 40/208 (19%)

Query: 61   LTTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVAS 120
            LT  A    + GS  A  P    DG AG     GE G  G P   G              
Sbjct: 1027 LTGPAGEPGREGSPGADGP-PGRDGAAGVKGDRGETGAVGAPGAPG-------------P 1072

Query: 121  PGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQK 180
            PG  G  G   ++G        RG   + G  G  G P    G+  P   R      G+ 
Sbjct: 1073 PGSPGPAGPTGKQG-------DRGEAGAQGPMGPSG-PAGARGIQGPQGPRGDKGEAGEP 1124

Query: 181  GECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECG 240
            GE G+    G        +G    PG  G+ G     G    P      V   G+ G  G
Sbjct: 1125 GERGLKGHRGFT----GLQGLPGPPGPSGDQGASGPAGPS-GPRGPPGPVGPSGKDGANG 1179

Query: 241  VPWREGAVWRPLDRRGSVASPGEKGECG 268
            +P             G +  PG +G  G
Sbjct: 1180 IP-------------GPIGPPGPRGRSG 1194



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 42/168 (25%), Positives = 57/168 (33%), Gaps = 39/168 (23%)

Query: 95  EKGEC---GIPWTEGQVWRPLERRASVASPG----------EKGEC---GVPWREGRVWR 138
           E G C   G  + +  VW+P   R  V   G          +  +C    +P+ E     
Sbjct: 30  EAGSCVQDGQRYNDKDVWKPEPCRICVCDTGTVLCDDIICEDVKDCLSPEIPFGECCPIC 89

Query: 139 PLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLER 198
           P D   +   PG KG+ G P     +  P         PG +G  G              
Sbjct: 90  PTDLATASGQPGPKGQKGEPGDIKDIVGPK------GPPGPQGPAG-------------E 130

Query: 199 RGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREG 246
           +G     G+KGE G P   GR   P     +  +PG  G  G P   G
Sbjct: 131 QGPRGDRGDKGEKGAPGPRGRDGEP----GTPGNPGPPGPPGPPGPPG 174


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 67/211 (31%), Positives = 88/211 (41%), Gaps = 24/211 (11%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
           PG V  PR  R   GE G   A G +G  G+P T G    P         PG +G  G+ 
Sbjct: 623 PGLV-GPRGERGFPGERGSPGAQGLQGPRGLPGTPG-TDGPKGASGPAGPPGAQGPPGLQ 680

Query: 131 WREGR-----VWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGEC 183
              G      +  P   RG V   GEKG  G P ++G  G+  P+       + G+KGE 
Sbjct: 681 GMPGERGAAGIAGPKGDRGDV---GEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEV 737

Query: 184 GVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPW 243
           G P   G         G+  +PGE+GE G P   G    P     +   PG KGE G   
Sbjct: 738 GPPGPAGSA-------GARGAPGERGETGPPGPAGFAGPP----GADGQPGAKGEQGEAG 786

Query: 244 REGAVWRPLDRRGSVASPGEKGECGVRWREG 274
           ++G    P   +G   +PG +G  GV   +G
Sbjct: 787 QKGDAGAP-GPQGPSGAPGPQGPTGVTGPKG 816



 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 64/216 (29%), Positives = 82/216 (37%), Gaps = 39/216 (18%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
           P   P P+    + G  G   A G  G  G P   G+V  P     S  +PG  G  G  
Sbjct: 799 PSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP----GSNGNPGPPGPPGPS 854

Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
            ++G    P   RG    PG  GE G+             +     PG+KGE G     G
Sbjct: 855 GKDG----PKGARGDSGPPGRAGEPGL-------------QGPAGPPGEKGEPGDDGPSG 897

Query: 191 GVWRP-----LERRGSVASPGEKGECGVPWREGRVWRPLERRASVAS-----------PG 234
               P       +RG V  PG++GE G P   G    P ++ A  AS           PG
Sbjct: 898 AEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPG 957

Query: 235 QKGECGVPWREGAVWR--PLDRRGSVASPGEKGECG 268
             G  G P REG+     P  R G+    G++GE G
Sbjct: 958 LTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETG 993



 Score = 69.3 bits (168), Expect = 4e-12
 Identities = 61/201 (30%), Positives = 75/201 (37%), Gaps = 29/201 (14%)

Query: 75  PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
           P    L  + G  G+    G KGE G P  +G+   P E      SPG  G  G+P   G
Sbjct: 209 PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN----GSPGPMGPRGLPGERG 264

Query: 135 RVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG--GV 192
           R   P    G+  + G+ G  G P   G    P        +PG KGE G     G  G 
Sbjct: 265 RT-GPAGAAGARGNDGQPGPAGPPGPVGPAGGP----GFPGAPGAKGEAGPTGARGPEGA 319

Query: 193 WRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPL 252
             P    G+  SPG  G  G P  +G              PG KG  G P   GA   P 
Sbjct: 320 QGPRGEPGTPGSPGPAGASGNPGTDG-------------IPGAKGSAGAPGIAGAPGFPG 366

Query: 253 DR-----RGSVASPGEKGECG 268
            R     +G+    G KG+ G
Sbjct: 367 PRGPPGPQGATGPLGPKGQTG 387



 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 59/201 (29%), Positives = 81/201 (40%), Gaps = 32/201 (15%)

Query: 81  RSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPL 140
           + + GEAG     G +GE G P   G          +    G +G  G P  +G    P 
Sbjct: 614 QGVPGEAGAPGLVGPRGERGFPGERGS-------PGAQGLQGPRGLPGTPGTDG----PK 662

Query: 141 DRRGSVASPGEKGECGVPWREG-----GVWRPLERRASVASPGQKGECGVPWREG--GVW 193
              G    PG +G  G+    G     G+  P   R  V   G+KG  G P ++G  G+ 
Sbjct: 663 GASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV---GEKGPEGAPGKDGGRGLT 719

Query: 194 RPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLD 253
            P+   G   + GEKGE G P        P     +  +PG++GE G P   G    P  
Sbjct: 720 GPIGPPGPAGANGEKGEVGPP-------GPAGSAGARGAPGERGETGPPGPAGFAGPP-- 770

Query: 254 RRGSVASPGEKGECGVRWREG 274
             G+   PG KGE G   ++G
Sbjct: 771 --GADGQPGAKGEQGEAGQKG 789



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 61/200 (30%), Positives = 71/200 (35%), Gaps = 34/200 (17%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
           P   P P      DGEAG    AGE+G  G     G    P         PG KG  G P
Sbjct: 172 PRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTP-------GLPGVKGHRGYP 224

Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
             +G        +G   +PG KGE G P   G             SPG  G  G+P  E 
Sbjct: 225 GLDG-------AKGEAGAPGVKGESGSPGENG-------------SPGPMGPRGLP-GER 263

Query: 191 GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREG--AV 248
           G   P    G+  + G+ G  G P   G    P        +PG KGE G     G    
Sbjct: 264 GRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGP----GFPGAPGAKGEAGPTGARGPEGA 319

Query: 249 WRPLDRRGSVASPGEKGECG 268
             P    G+  SPG  G  G
Sbjct: 320 QGPRGEPGTPGSPGPAGASG 339



 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 63/231 (27%), Positives = 88/231 (38%), Gaps = 32/231 (13%)

Query: 70  KPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLER-----RASVASPGEK 124
           +PG+  +P P  +  G  G     G KG  G P   G    P  R     + +    G K
Sbjct: 325 EPGTPGSPGPAGA-SGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPK 383

Query: 125 GECGVPWREGRVWR--------PLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVAS 176
           G+ G P   G            P   +G+    GE+G+ G     GGV  P+       +
Sbjct: 384 GQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVG-PIGPPGERGA 442

Query: 177 PGQKGECGVPWREGGVWRPLER--------RGSVASPGEKGECGVPWREGRVWRPLE--- 225
           PG +G  G     G    P ER        +G+   PG  GE G+P   G   RP +   
Sbjct: 443 PGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGP 502

Query: 226 --RRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREG 274
             +     +PG+ G  G P  +GA  +P    G +  PG KG  G   + G
Sbjct: 503 QGKVGPSGAPGEDGRPGPPGPQGARGQP----GVMGFPGPKGANGEPGKAG 549



 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 62/234 (26%), Positives = 86/234 (36%), Gaps = 50/234 (21%)

Query: 75  PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWR--------PLERRASVASPGEKGE 126
           P P+      G+AG     G  G  G+P  +G+           P   R    +PG  G 
Sbjct: 536 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 595

Query: 127 CGV---PWREGRVWRPLDR--------------RGSVASPGEKGECGVPWREG------- 162
            G+   P   G   +P D+              RG    PGE+G  G    +G       
Sbjct: 596 QGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGT 655

Query: 163 -GVWRPLERRASVASPGQKGECGVPWREG-----GVWRPLERRGSVASPGEKGECGVPWR 216
            G   P         PG +G  G+    G     G+  P   RG V   GEKG  G P +
Sbjct: 656 PGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV---GEKGPEGAPGK 712

Query: 217 EG--RVWRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECG 268
           +G   +  P+       + G+KGE G P   G+        G+  +PGE+GE G
Sbjct: 713 DGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSA-------GARGAPGERGETG 759



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 59/208 (28%), Positives = 70/208 (33%), Gaps = 32/208 (15%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
           P     PR  R   GE G     G  GE G P   G              PG  G  G P
Sbjct: 58  PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPG-------------PPGPPGPPGPP 104

Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
              G         G         + GV     G   P        +PG +G  G P   G
Sbjct: 105 GLGGNF--AAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG 162

Query: 191 --GVWRPLERR---GSVASPGEKGECGVPWREGRVWRPLERRA-----SVASPGQKGECG 240
             GV  P+  R   G    PG+ GE G P + G    P  + A     +   PG KG  G
Sbjct: 163 EPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRG 222

Query: 241 VPWREGAVWRPLDRRGSVASPGEKGECG 268
            P  +GA       +G   +PG KGE G
Sbjct: 223 YPGLDGA-------KGEAGAPGVKGESG 243



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 53/208 (25%), Positives = 66/208 (31%), Gaps = 40/208 (19%)

Query: 61   LTTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVAS 120
            LT  A    + GS  A  P    DG AG     GE G  G P   G              
Sbjct: 958  LTGPAGEPGREGSPGADGP-PGRDGAAGVKGDRGETGAVGAPGAPG-------------P 1003

Query: 121  PGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQK 180
            PG  G  G   ++G        RG   + G  G  G P    G+  P   R      G+ 
Sbjct: 1004 PGSPGPAGPTGKQG-------DRGEAGAQGPMGPSG-PAGARGIQGPQGPRGDKGEAGEP 1055

Query: 181  GECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECG 240
            GE G+    G        +G    PG  G+ G     G    P      V   G+ G  G
Sbjct: 1056 GERGLKGHRGFT----GLQGLPGPPGPSGDQGASGPAGPS-GPRGPPGPVGPSGKDGANG 1110

Query: 241  VPWREGAVWRPLDRRGSVASPGEKGECG 268
            +P             G +  PG +G  G
Sbjct: 1111 IP-------------GPIGPPGPRGRSG 1125



 Score = 31.6 bits (70), Expect = 0.91
 Identities = 43/163 (26%), Positives = 54/163 (33%), Gaps = 35/163 (21%)

Query: 118 VASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASP 177
           V  PG KG+ G P     +  P    G     GE+G  G                     
Sbjct: 28  VRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRG-------------------DR 68

Query: 178 GQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREG-------RVWRPLERRASV 230
           G KGE G P   G    P    G+  +PG  G  G P   G       ++    + +A  
Sbjct: 69  GDKGEKGAPGPRGRDGEP----GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGG 124

Query: 231 AS----PGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECGV 269
           A      G  G  G     G    P   +G   +PGE GE GV
Sbjct: 125 AQLGVMQGPMGPMGPRGPPGPAGAP-GPQGFQGNPGEPGEPGV 166


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score = 72.8 bits (177), Expect = 4e-13
 Identities = 66/210 (31%), Positives = 86/210 (40%), Gaps = 39/210 (18%)

Query: 84   DGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASV------ASPGEKGECGVPWREGRVW 137
            DG+AG     G KG+ GI  T G    P   + SV       +PGEKG  G+P  +G   
Sbjct: 980  DGQAGQPGQPGPKGDPGISGTPGAPGLP-GPKGSVGGMGLPGTPGEKGVPGIPGPQGSPG 1038

Query: 138  RPLDR-----RGSVASP--------GEKGECGVPWREGGVWRPLERRASVASPGQKGECG 184
             P D+     +G    P        GEKG+ G+    G      E + S+  PG  G  G
Sbjct: 1039 LPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGE-KGSIGIPGMPGSPG 1097

Query: 185  VPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWR 244
            +    G V  P    GS   PGEKG+ G+P  +G              PG KGE G+P  
Sbjct: 1098 LKGSPGSVGYP----GSPGLPGEKGDKGLPGLDG-------------IPGVKGEAGLPGT 1140

Query: 245  EGAVWRPLDRRGSVASPGEKGECGVRWREG 274
             G    P  ++G   S G  G  G +   G
Sbjct: 1141 PGPT-GPAGQKGEPGSDGIPGSAGEKGEPG 1169



 Score = 68.6 bits (166), Expect = 7e-12
 Identities = 59/196 (30%), Positives = 84/196 (42%), Gaps = 34/196 (17%)

Query: 85   GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
            G  G   + G+ G  G+P  +GQ  +P         PG KG+ G+    G    P   +G
Sbjct: 960  GPIGEKGSRGDPGTPGVPGKDGQAGQP-------GQPGPKGDPGISGTPGAPGLP-GPKG 1011

Query: 145  SV------ASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLER 198
            SV       +PGEKG  G+P  +G    P ++ A     G+KG+ G P    G+  P   
Sbjct: 1012 SVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAK----GEKGQAGPP----GIGIP--- 1060

Query: 199  RGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSV 258
             G     G++G  G P   G        + S+  PG  G  G+    G+V  P    GS 
Sbjct: 1061 -GLRGEKGDQGIAGFPGSPGE----KGEKGSIGIPGMPGSPGLKGSPGSVGYP----GSP 1111

Query: 259  ASPGEKGECGVRWREG 274
              PGEKG+ G+   +G
Sbjct: 1112 GLPGEKGDKGLPGLDG 1127



 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 70/211 (33%), Positives = 86/211 (40%), Gaps = 41/211 (19%)

Query: 71   PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVA----SPGEKGE 126
            PG +P P+    + G+ G   A GEKG+ G P       R  +    +A    SPGEKGE
Sbjct: 1028 PG-IPGPQGSPGLPGDKG---AKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGE 1083

Query: 127  CG------VPWREGRVWRP--LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPG 178
             G      +P   G    P  +   GS   PGEKG+ G+P  +G              PG
Sbjct: 1084 KGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDG-------------IPG 1130

Query: 179  QKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRP-LERRASVASPGQKG 237
             KGE G+P   G         G     GE G  G+P   G    P L  R     PG KG
Sbjct: 1131 VKGEAGLPGTPGPT-------GPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKG 1183

Query: 238  ECGVPWREGAVWRPLDRRGSVASPGEKGECG 268
            + G    +G V  P    GS   PG KGE G
Sbjct: 1184 DKG---SKGEVGFP-GLAGSPGIPGSKGEQG 1210



 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 65/231 (28%), Positives = 100/231 (43%), Gaps = 39/231 (16%)

Query: 71   PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRP-----LERRASVASPGEKG 125
            PG V AP  L    G+ G   ++G +G+ G+   +G V  P     +++    +  G+KG
Sbjct: 893  PGPVGAPG-LPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKG 951

Query: 126  ECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGV 185
            + G   + G    P+  +GS   PG  G   VP ++G   +P         PG KG+ G+
Sbjct: 952  DQGEKGQIG----PIGEKGSRGDPGTPG---VPGKDGQAGQP-------GQPGPKGDPGI 997

Query: 186  PWREGGVWRPLERRGSVA------SPGEKGECGVPWREGRVWRPLERRAS---------- 229
                G    P   +GSV       +PGEKG  G+P  +G    P ++ A           
Sbjct: 998  SGTPGAPGLP-GPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPG 1056

Query: 230  VASPGQKGECGVPWREGAVWRPLDR--RGSVASPGEKGECGVRWREGRVWY 278
            +  PG +GE G     G    P ++  +GS+  PG  G  G++   G V Y
Sbjct: 1057 IGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGY 1107



 Score = 65.5 bits (158), Expect = 6e-11
 Identities = 67/228 (29%), Positives = 90/228 (39%), Gaps = 50/228 (21%)

Query: 71   PG-SVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGV 129
            PG  +P P+      G+ G     G  G+ G+P   GQ   P         PG KGE GV
Sbjct: 834  PGLDMPGPK------GDKGAQGLPGITGQSGLPGLPGQQGAP----GIPGFPGSKGEMGV 883

Query: 130  PWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWRE 189
                G+   P    G+   PGEKG+ G P   G        R      G KG+ G+P + 
Sbjct: 884  MGTPGQPGSP-GPVGAPGLPGEKGDHGFPGSSG-------PRGDPGLKGDKGDVGLPGKP 935

Query: 190  G-----------GVWRPLERRGSVASPGEKGE------CGVPWREGRVWRPLERRASVAS 232
            G           G       +G +   GEKG        GVP ++G+  +P         
Sbjct: 936  GSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQP-------GQ 988

Query: 233  PGQKGECGVPWREGAVWRPLDRRGSV------ASPGEKGECGVRWREG 274
            PG KG+ G+    GA   P   +GSV       +PGEKG  G+   +G
Sbjct: 989  PGPKGDPGISGTPGAPGLP-GPKGSVGGMGLPGTPGEKGVPGIPGPQG 1035



 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 62/213 (29%), Positives = 85/213 (39%), Gaps = 22/213 (10%)

Query: 67  LSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGE 126
           +   PG +    P   + GE G     G  G  G+P  +G V  P         PG  G 
Sbjct: 155 MKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPP----GFTGPPGPPGP 210

Query: 127 CGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVP 186
            G P  +G++   L  +G     G++G  G P   G     ++ +   A+ G+KG+ G P
Sbjct: 211 PGPPGEKGQM--GLSFQGPKGDKGDQGVSGPPGVPGQA--QVQEKGDFATKGEKGQKGEP 266

Query: 187 WREG--GVWRPLE-----RRGSVASPGEKGECGVPWREGRVWRP--LERRASVASPGQKG 237
             +G  GV    E      RG     G+KGE G P   G    P  + R+      G+KG
Sbjct: 267 GFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQ---GPQGEKG 323

Query: 238 ECGVPWREGAV--WRPLDRRGSVASPGEKGECG 268
           E G P   G V    PL  +G    PG  G  G
Sbjct: 324 EAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRG 356



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 58/194 (29%), Positives = 80/194 (41%), Gaps = 16/194 (8%)

Query: 85  GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
           G  G    AG  G  G+P  +G     L     +   GE+G  G+P   G    P   +G
Sbjct: 136 GPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLP-GLQG 194

Query: 145 SVASPGEKGECGVPWREGGVWRPLERRASVASP-GQKGECGVPWREGGVWR-PLERRGSV 202
            V  PG  G  G P   G      +   S   P G KG+ GV    G   +  ++ +G  
Sbjct: 195 PVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDF 254

Query: 203 ASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDR--RGSVAS 260
           A+ GEKG+ G P  +G           +   G+KGE G P   G   +  D+  +GS   
Sbjct: 255 ATKGEKGQKGEPGFQG-----------MPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGF 303

Query: 261 PGEKGECGVRWREG 274
           PGE G  G+  R+G
Sbjct: 304 PGEPGYPGLIGRQG 317



 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 56/204 (27%), Positives = 78/204 (38%), Gaps = 15/204 (7%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
           PG  P  +  R + G  G +   G +G  G+    G    P E    +   G+KG+ G P
Sbjct: 491 PGQ-PGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFP 549

Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREG-----GVWRPLERRASVASPGQKGECGV 185
            + G         G   SPG  G  G+P  +G     G+         V  PG +G+ G 
Sbjct: 550 GQPGMT-------GRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGP 602

Query: 186 PWREG-GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWR 244
           P   G G   P+  +G    PG  G  G+P  +G   + +       + G  G  G P  
Sbjct: 603 PGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGP 662

Query: 245 EGAVWRPLDRRGSVASPGEKGECG 268
           +G    P    G    PGEKG  G
Sbjct: 663 QGDRGFP-GTPGRPGLPGEKGAVG 685



 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 61/215 (28%), Positives = 83/215 (38%), Gaps = 28/215 (13%)

Query: 67  LSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGE 126
           L  +PG    P P ++  G  G     GEKG+ G P T   +  P  R      PG  G 
Sbjct: 366 LPGQPGPPGLPVPGQA--GAPGFPGERGEKGDRGFPGTS--LPGPSGRDGLPGPPGSPGP 421

Query: 127 CGVP-WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGE--- 182
            G P +  G V            PG++G  G+P + G +         +   GQKGE   
Sbjct: 422 PGQPGYTNGIV------ECQPGPPGDQGPPGIPGQPGFI-------GEIGEKGQKGESCL 468

Query: 183 -CGVPWREG--GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGEC 239
            C +    G  G   P    G    PG KG+ G+P R+G    P        +PG  G+ 
Sbjct: 469 ICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVP----GPQGTPGLIGQP 524

Query: 240 GVPWREGAVWRPLDRRGSVASPGEKGECGVRWREG 274
           G     G  +  L  +G    PG  G+ G+  R G
Sbjct: 525 GAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAG 559



 Score = 58.2 bits (139), Expect = 9e-09
 Identities = 60/192 (31%), Positives = 75/192 (39%), Gaps = 26/192 (13%)

Query: 80  LRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRP 139
           L+ + G  G     GEKG  G+P   G+         ++  PG +G  G P        P
Sbjct: 741 LKGLPGLPGIPGTPGEKGSIGVPGVPGE-------HGAIGPPGLQGIRGEP-------GP 786

Query: 140 LDRRGSVASPGEK--GECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG-GVWRPL 196
               GSV SPG    G  G     GG   P         PG KGE G P   G  +  P 
Sbjct: 787 PGLPGSVGSPGVPGIGPPGARGPPGGQGPP----GLSGPPGIKGEKGFPGFPGLDMPGPK 842

Query: 197 ERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDRRG 256
             +G+   PG  G+ G+P   G+   P         PG KGE GV    G    P    G
Sbjct: 843 GDKGAQGLPGITGQSGLPGLPGQQGAP----GIPGFPGSKGEMGVMGTPGQPGSP-GPVG 897

Query: 257 SVASPGEKGECG 268
           +   PGEKG+ G
Sbjct: 898 APGLPGEKGDHG 909



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 62/199 (31%), Positives = 75/199 (37%), Gaps = 31/199 (15%)

Query: 85  GEAGHSEAAGEKGECGIPWTEGQ--VWRPLERRASVASPGEKGECGVPWREGRVWRPLDR 142
           GE G     G KG+ G+P  +G   V  P      +  PG KGE G  + + R+      
Sbjct: 486 GEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGD 545

Query: 143 RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSV 202
            G    PG  G  G P R+G    P   + S  S G KGE G P   GGV  P   RG  
Sbjct: 546 PGFPGQPGMTGRAGSPGRDGHPGLP-GPKGSPGSVGLKGERGPP---GGVGFP-GSRGDT 600

Query: 203 ASPG-----------EKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRP 251
             PG           +KG+ G P   G             SPG  G  G P +   +  P
Sbjct: 601 GPPGPPGYGPAGPIGDKGQAGFPGGPG-------------SPGLPGPKGEPGKIVPLPGP 647

Query: 252 LDRRGSVASPGEKGECGVR 270
               G   SPG  G  G R
Sbjct: 648 PGAEGLPGSPGFPGPQGDR 666



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 60/217 (27%), Positives = 83/217 (38%), Gaps = 42/217 (19%)

Query: 94  GEKGECGIPWTEGQVWRPLERRASVASPGEKGECG--VPWREGRVWRPLDR-----RG-- 144
           GEKGE G P T G    P   +     PG+ G  G  VP + G    P +R     RG  
Sbjct: 341 GEKGERGYPGTPGPRGEP-GPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFP 399

Query: 145 SVASPGEKGECGVPWREGGVWRPLER-------RASVASPGQKGECGVPWREGGVWRPLE 197
             + PG  G  G+P   G    P +              PG +G  G+P + G +     
Sbjct: 400 GTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFI----- 454

Query: 198 RRGSVASPGEKGEC----------GVPWREGRVWRPLERRASVASPGQKGECGVPWREGA 247
             G +   G+KGE           G P  +G    P         PG KG+ G+P R+G 
Sbjct: 455 --GEIGEKGQKGESCLICDIDGYRGPPGPQG----PPGEIGFPGQPGAKGDRGLPGRDGV 508

Query: 248 VWRPLDRRGSVASPGEKGECGVRWREGRVWYSLDKRG 284
              P    G   +PG  G+ G +   G  ++ L  +G
Sbjct: 509 AGVP----GPQGTPGLIGQPGAKGEPGEFYFDLRLKG 541



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 53/204 (25%), Positives = 79/204 (38%), Gaps = 27/204 (13%)

Query: 84  DGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRP---- 139
           +G  G     G+ GE G+P T+G    P     +   PG  G  G+P ++G    P    
Sbjct: 69  EGPQGPPGQKGDTGEPGLPGTKGTRGPP----GASGYPGNPGLPGIPGQDGPPGPPGIPG 124

Query: 140 ----LDRRGSVASP------GEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWRE 189
                  RG +  P      G  G  G+P  +G     L     +   G++G  G+P   
Sbjct: 125 CNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTP 184

Query: 190 G-----GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWR 244
           G     G+  P+   G    PG  G  G P  +G++   L  +      G +G  G P  
Sbjct: 185 GPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQM--GLSFQGPKGDKGDQGVSGPPGV 242

Query: 245 EGAVWRPLDRRGSVASPGEKGECG 268
            G     +  +G  A+ GEKG+ G
Sbjct: 243 PGQA--QVQEKGDFATKGEKGQKG 264



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 59/197 (29%), Positives = 69/197 (35%), Gaps = 52/197 (26%)

Query: 71  PGS--VPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECG 128
           PGS   P P+  R   G  G     GEKG  G P               +  PG  G  G
Sbjct: 654 PGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQP--------------GIGFPGPPGPKG 699

Query: 129 VPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWR 188
           V    G +  P    G+   PG  G  G P  +G    P      V  PG KG  G+P  
Sbjct: 700 VDGLPGDMGPP----GTPGRPGFNGLPGNPGVQGQKGEP-----GVGLPGLKGLPGLP-- 748

Query: 189 EGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAV 248
                      G   +PGEKG  GVP   G          ++  PG +G  G P   G  
Sbjct: 749 -----------GIPGTPGEKGSIGVPGVPG-------EHGAIGPPGLQGIRGEPGPPGL- 789

Query: 249 WRPLDRRGSVASPGEKG 265
                  GSV SPG  G
Sbjct: 790 ------PGSVGSPGVPG 800



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 53/189 (28%), Positives = 76/189 (40%), Gaps = 19/189 (10%)

Query: 94  GEKGECGIPWTEGQVWRPLER--RASVASPGEK---GECGVPWREGRVWRPLDRRGSVAS 148
           G+KGE G+P  +G +  P  +        PG+K   GE G+P  +G    P    G+   
Sbjct: 46  GQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPP----GASGY 101

Query: 149 PGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVASPGEK 208
           PG  G  G+P ++G    P     +  + G++G  G P   G    P    G    PG K
Sbjct: 102 PGNPGLPGIPGQDGPPGPPGIPGCN-GTKGERGPLGPPGLPGFAGNP----GPPGLPGMK 156

Query: 209 GECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAV-----WRPLDRRGSVASPGE 263
           G+ G              R     PG  G  G+P  +G V       P    G    PGE
Sbjct: 157 GDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGE 216

Query: 264 KGECGVRWR 272
           KG+ G+ ++
Sbjct: 217 KGQMGLSFQ 225



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 63/208 (30%), Positives = 79/208 (37%), Gaps = 33/208 (15%)

Query: 67   LSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEG----QVWRPLERRASV-ASP 121
            L   PG +  P  L  IDG  G     G  G  G+P  +G    Q    +     +  S 
Sbjct: 1246 LPGLPGPM-GPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSK 1304

Query: 122  GEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQ-- 179
            G+ G  GVP  +G    P    G     G++G+ GVP  +G    P         PG   
Sbjct: 1305 GDMGPPGVPGFQG----PKGLPGLQGIKGDQGDQGVPGAKGLPGPP-------GPPGPYD 1353

Query: 180  --KGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKG 237
              KGE G+P  EG    P   +G    PG KG+ GV    G +  P        +PGQKG
Sbjct: 1354 IIKGEPGLPGPEG----PPGLKGLQGLPGPKGQQGVTGLVG-IPGPPGIPGFDGAPGQKG 1408

Query: 238  ECGVPWREGAVWRPLDRRGSVASPGEKG 265
            E G          P   RG    PG  G
Sbjct: 1409 EMGPA-------GPTGPRGFPGPPGPDG 1429


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score = 72.0 bits (175), Expect = 6e-13
 Identities = 68/216 (31%), Positives = 87/216 (40%), Gaps = 28/216 (12%)

Query: 67  LSAKPGS-----VPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASP 121
           L+ +PG      +P    LR   GE G +   GEKGE G+P   G        R      
Sbjct: 248 LNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFP----GVRGEKGDQ 303

Query: 122 GEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASP-GQK 180
           GEKGE G+P  +G        RG     G  G  G+P     ++ P  R      P G+K
Sbjct: 304 GEKGELGLPGLKG-------DRGEKGEAGPAGPPGLPGTT-SLFTPHPRMPGEQGPKGEK 355

Query: 181 GECGVPWREGGVWRP--LERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGE 238
           G+ G+P   G   RP  L  +G    PG KG+ G     G    P        +PG  G 
Sbjct: 356 GDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNP-------GAPGHVGA 408

Query: 239 CGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREG 274
            G     G+V  P   RG+    GE+GE G    EG
Sbjct: 409 PGPSGPPGSVGAP-GLRGTPGKDGERGEKGAAGEEG 443



 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 69/233 (29%), Positives = 92/233 (39%), Gaps = 47/233 (20%)

Query: 68  SAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRP--LERRASVASPGEKG 125
           S  PG +P        DG+ G     G+ GE G+P  EG    P          +PG +G
Sbjct: 680 SGLPG-IPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRG 738

Query: 126 ECG---VPWREGRVWR-----------------PLDRRGSVASPGEKGECGVPWREG--- 162
           E G   +P +EG   +                 P  + GS  SPGE G  G P ++G   
Sbjct: 739 ESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKG 798

Query: 163 -----GVWRPLERRASVASPGQKGECGVPWREGGVWRPLER--RGSVASPGEKGECGVPW 215
                G+   L  R     PG+ GE GVP +EG   +P E   +G    PG KG+ G P 
Sbjct: 799 ENGSPGLPGFLGPR---GPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPG 855

Query: 216 REGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECG 268
            +G+   P         PG KG  G+   +G         G V  PG  G+ G
Sbjct: 856 GKGQPGDP-------GIPGHKGHTGLMGPQGLP----GENGPVGPPGPPGQPG 897



 Score = 65.1 bits (157), Expect = 7e-11
 Identities = 70/259 (27%), Positives = 97/259 (37%), Gaps = 58/259 (22%)

Query: 69  AKPGSVPAPRPL---RSIDGEAGHSEAAGEKGECGIPWTEGQVWRP-------LERRASV 118
           A P  +P P  +   +   GE G     G+KG+ G P   G +  P        +  A  
Sbjct: 599 AGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGA 658

Query: 119 ASP----------------GEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREG 162
           A P                G  G  G+P  EG+  R   + G    PG+ GE G+P  EG
Sbjct: 659 AGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRD-GKPGPPGEPGKAGEPGLPGPEG 717

Query: 163 GVWRP--LERRASVASPGQKGE---CGVPWREG-----------------GVWRPLERRG 200
               P          +PG +GE    G+P +EG                 G   P  + G
Sbjct: 718 ARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNG 777

Query: 201 SVASPGEKGECGVPWREGRVWRPLER-----RASVASPGQKGECGVPWREGAVWRPLDRR 255
           S  SPGE G  G P ++G                   PG+ GE GVP +EG   +P    
Sbjct: 778 SPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKP---- 833

Query: 256 GSVASPGEKGECGVRWREG 274
           G     GE+G+ G++  +G
Sbjct: 834 GEPGFKGERGDPGIKGDKG 852



 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 70/237 (29%), Positives = 86/237 (36%), Gaps = 42/237 (17%)

Query: 68  SAKPGSVPAP--RPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRP-LERRASVASPGEK 124
           S  PGSV AP  R     DGE G   AAGE+G  G     G    P L         GE 
Sbjct: 412 SGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEP 471

Query: 125 GECGVPWREGRVWRPLDR--RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGE 182
           G  G P   G +    DR   G   SPG +G+ G+     G   P        SPG +G 
Sbjct: 472 GLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGI--GVAGPPGPSGPPGDKGSPGSRGL 529

Query: 183 CGVPWREGGVWR-----------------------PLERRGSVASPGEKGECGVPWREGR 219
            G P  +G   R                       P    G    PG KG+ GVP + GR
Sbjct: 530 PGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGR 589

Query: 220 VWRPLERRASVASPGQKGECGVPWREG--AVWRPLDRRGSVASPGEKGECGVRWREG 274
                       + G+KGE G P   G   +  P   +G   + GE G+ G +   G
Sbjct: 590 ----------EGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPG 636



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 55/228 (24%), Positives = 77/228 (33%), Gaps = 65/228 (28%)

Query: 83   IDGEAGHSEAAGEKGECGIPWTEGQVWR------PLERRASVASPGEKGECGVPWREGR- 135
            I G+ G     G+ G+ GIP  +G          P E    V  PG  G+ G P   G  
Sbjct: 847  IKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGEN-GPVGPPGPPGQPGFPGLRGES 905

Query: 136  -------------VWRPLDRR-----------------GSVASPGEKGECGVPWREGGVW 165
                         + + L+ R                 G    PG  G+ G+P R G   
Sbjct: 906  PSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAG--- 962

Query: 166  RPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVASPGE-----KGECGVPWREGRV 220
                    +  PG+ G+ G+    G +  P   RG+   PG      +GE G P   G+ 
Sbjct: 963  -------PMGEPGRPGQGGLEGPSGPI-GPKGERGAKGDPGAPGVGLRGEMGPPGIPGQP 1014

Query: 221  WRPLERRASVAS-PGQKGECGVPWREGAVWRPLDRRGSVASPGEKGEC 267
              P   +  +   PG +GE G          P    G    PG  G+C
Sbjct: 1015 GEPGYAKDGLPGIPGPQGETG----------PAGHPGLPGPPGPPGQC 1052


>gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]
          Length = 1714

 Score = 71.6 bits (174), Expect = 8e-13
 Identities = 61/215 (28%), Positives = 83/215 (38%), Gaps = 35/215 (16%)

Query: 71   PGSV--PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECG 128
            PG +    P+  R   G  GH    G  GE GIP   G   +P         PG KGE G
Sbjct: 1136 PGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQP----GPSGLPGPKGEKG 1191

Query: 129  VPWREGRVWRPLDRRGSVASPGEKGECGVPWREG--------GVWRPLERRASVASPGQK 180
             P  +  V  P   RG     G++GE G P  EG        G+     ++     PG +
Sbjct: 1192 YPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQ 1251

Query: 181  GECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECG 240
            GE G+    G        +G   +PG  G+ G+P  +G +             G KG  G
Sbjct: 1252 GEQGLKGERGSE----GNKGKKGAPGPSGKPGIPGLQGLL-------------GPKGIQG 1294

Query: 241  VPWREGAVWRPLDRRGSVASPGEKGECGVRWREGR 275
                +G    P    G +  PG++G  G+R   GR
Sbjct: 1295 YHGADGISGNP----GKIGPPGKQGLPGIRGGPGR 1325



 Score = 70.1 bits (170), Expect = 2e-12
 Identities = 65/209 (31%), Positives = 81/209 (38%), Gaps = 34/209 (16%)

Query: 85   GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDR-- 142
            GE G   A GEKG+ G     G + +         +PGE+G  G P  +G      DR  
Sbjct: 936  GEQGIQGAKGEKGDQGKRGPHGLIGK-------TGNPGERGFQGKPGLQGLPGSTGDRGL 988

Query: 143  ---------RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVW 193
                     +G V  PGE G  G P  EG              PG KG+ G     GG  
Sbjct: 989  PGEPGLRGLQGDVGPPGEMGMEGPPGTEG-------ESGLQGEPGAKGDVGTAGSVGGTG 1041

Query: 194  RPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLD 253
             P    G    PG  GE G+  ++G    P   R      G+KGE G+P   G    PL 
Sbjct: 1042 EP----GLRGEPGAPGEEGLQGKDGLKGVP-GGRGLPGEDGEKGEMGLPGIIG----PLG 1092

Query: 254  RRGSVASPGEKGECGVRWREGRVWYSLDK 282
            R G    PG +G  G+  + GR     DK
Sbjct: 1093 RSGQTGLPGPEGIVGIPGQRGRPGKKGDK 1121



 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 65/213 (30%), Positives = 84/213 (39%), Gaps = 44/213 (20%)

Query: 67   LSAKPGS-----VPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASP 121
            L   PGS     +P    LR + G+ G     GE G  G P TEG+             P
Sbjct: 976  LQGLPGSTGDRGLPGEPGLRGLQGDVG---PPGEMGMEGPPGTEGE-------SGLQGEP 1025

Query: 122  GEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKG 181
            G KG+ G     G    P    G    PG  GE G+  ++G    P   R      G+KG
Sbjct: 1026 GAKGDVGTAGSVGGTGEP----GLRGEPGAPGEEGLQGKDGLKGVP-GGRGLPGEDGEKG 1080

Query: 182  ECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGV 241
            E G+P    G+  PL R G    PG +G  G+P + GR             PG+KG+ G 
Sbjct: 1081 EMGLP----GIIGPLGRSGQTGLPGPEGIVGIPGQRGR-------------PGKKGDKGQ 1123

Query: 242  PWREGAVWRPLDRRGSVASPGEKGECGVRWREG 274
                G V       GS   PG+ G+ G +   G
Sbjct: 1124 IGPTGEV-------GSRGPPGKIGKSGPKGARG 1149



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 62/226 (27%), Positives = 86/226 (38%), Gaps = 34/226 (15%)

Query: 71   PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRAS---VASPGEKGEC 127
            P   P     R   G+ G S   G KGE G P  +  V  P   R     V   GE+GE 
Sbjct: 1162 PDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEP 1221

Query: 128  GVPWREGRVWRP-----LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGE 182
            G    +G V  P       ++G    PG++GE G+    G        +    +PG  G+
Sbjct: 1222 GAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSE----GNKGKKGAPGPSGK 1277

Query: 183  CGVPWREG-----------GVWRPLERRGSVASPGEKGECGV---PWREGRVWRPLERRA 228
             G+P  +G           G        G +  PG++G  G+   P R G    P     
Sbjct: 1278 PGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAP----- 1332

Query: 229  SVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREG 274
                PG KG  G+P   G +  P   +G    PG +G+ G R  +G
Sbjct: 1333 --GPPGVKGSSGLPGSPG-IQGPKGEQGLPGQPGIQGKRGHRGAQG 1375



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 62/211 (29%), Positives = 85/211 (40%), Gaps = 38/211 (18%)

Query: 71  PGSVPAP------RPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEK 124
           P  +P P      + L  I G+ G    AGE GE G P  +G V  P         PG +
Sbjct: 694 PAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLP-------GPPGMR 746

Query: 125 GECGVPWREGRVWRPLDRRGSVASPGEK---GECGVPWREG--GVWRPLERRASVASPGQ 179
           G+ G   + G        +G    PG +   G+ G+P + G  G    L  R     PG 
Sbjct: 747 GKSGPSGQTG----DPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGL 802

Query: 180 KGECGVPWREG--GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKG 237
           KG  G    EG  G +  L  RG    PG+KG  G P  EG +   +  + ++   G+ G
Sbjct: 803 KGTQG---EEGPIGAFGELGPRG---KPGQKGYAGEPGPEG-LKGEVGDQGNIGKIGETG 855

Query: 238 ECGVPWREGAVWRPLDRRGSVASPGEKGECG 268
             G+P   G         GS+   GE+G  G
Sbjct: 856 PVGLPGEVGMT-------GSIGEKGERGSPG 879



 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 62/208 (29%), Positives = 78/208 (37%), Gaps = 37/208 (17%)

Query: 77  PRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRV 136
           P  ++   G  GH    G  GE GIP   G          ++ SPG  G  G+   EG  
Sbjct: 562 PPGMQGDKGLKGHPGLPGLPGEQGIPGFAG----------NIGSPGYPGRQGLAGPEGNP 611

Query: 137 WRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG--GVWR 194
             P   +G + SPGE G+ G P  E G+            PG +G+ G   R+G  G + 
Sbjct: 612 -GPKGAQGFIGSPGEAGQLG-PEGERGI------------PGIRGKKGFKGRQGFPGDFG 657

Query: 195 PLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDR 254
                G   SPG  G  G P   G        R SV   G  G  G+P   G        
Sbjct: 658 DRGPAGLDGSPGLVGGTGPPGFPG-------LRGSVGPVGPIGPAGIPGPMGL----SGN 706

Query: 255 RGSVASPGEKGECGVRWREGRVWYSLDK 282
           +G     G+KGE G     G   Y  DK
Sbjct: 707 KGLPGIKGDKGEQGTAGELGEPGYPGDK 734



 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 57/214 (26%), Positives = 83/214 (38%), Gaps = 12/214 (5%)

Query: 69  AKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECG 128
           A P   P P+  +   G  G +   G +GE GIP   G+      R+      G++G  G
Sbjct: 605 AGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFK-GRQGFPGDFGDRGPAG 663

Query: 129 VPWREGRVWRPLDRRGSVASPGEKGECGV--PWREGGVWRPLERRASVASPGQKGECGVP 186
           +    G V       G    PG +G  G   P    G+  P+    +   PG KG+ G  
Sbjct: 664 LDGSPGLV----GGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQ 719

Query: 187 WREGGVWRP--LERRGSVASPGEKGECGVPWREGRVWRP-LERRASVASP-GQKGECGVP 242
              G +  P     +G+V  PG  G  G     G+   P L+  +    P G  G+ G+P
Sbjct: 720 GTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIP 779

Query: 243 WREGAVWRPLDRRGSVASPGEKGECGVRWREGRV 276
            + G    P    G+   PG  G  G +  EG +
Sbjct: 780 GQNGPE-GPKGLLGNRGPPGPPGLKGTQGEEGPI 812



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 39/145 (26%), Positives = 55/145 (37%), Gaps = 28/145 (19%)

Query: 83   IDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDR 142
            I G+ GH  A G++G CG P  +GQ             PGE G  G+   +G        
Sbjct: 1364 IQGKRGHRGAQGDQGPCGDPGLKGQ-------------PGEYGVQGLTGFQG-------F 1403

Query: 143  RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSV 202
             G     G+ G  G+   +G    P+  R +    G++G  G   R G    P   +G  
Sbjct: 1404 PGPKGPEGDAGIVGISGPKG----PIGHRGNTGPLGREGIIGPTGRTG----PRGEKGFR 1455

Query: 203  ASPGEKGECGVPWREGRVWRPLERR 227
               G +G  G P   G    P  R+
Sbjct: 1456 GETGPQGPRGQPGPPGPPGAPGPRK 1480



 Score = 33.5 bits (75), Expect = 0.24
 Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 6/105 (5%)

Query: 178 GQKGECGVPWREG--GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVAS--P 233
           G KG+ G P   G  G+  P  +RG    PG  G  G+P   G      +   S     P
Sbjct: 489 GPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVP 548

Query: 234 GQKGECGVPWREGAVWRPLDR--RGSVASPGEKGECGVRWREGRV 276
           G+KG+ G+    G      D+  +G    PG  GE G+    G +
Sbjct: 549 GEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNI 593


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
           sapiens]
          Length = 1818

 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 66/219 (30%), Positives = 86/219 (39%), Gaps = 27/219 (12%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
           P   P PR ++  DG  G   + GEKGE G P  +G +    + R  V   G +GE G  
Sbjct: 767 PIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGD-RGEVGQIGPRGEDGPE 825

Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGV--- 185
             +GR   P    G     GEKG+ GVP   G  G   P         PG  GE G    
Sbjct: 826 GPKGRA-GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV 884

Query: 186 -----PWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLER-----RASVASPGQ 235
                P  + G   P   RG+    G+ G  G    +G    P ER     +  V  PG 
Sbjct: 885 AGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP 944

Query: 236 KGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREG 274
           KG  G P ++G              PG++GE G + + G
Sbjct: 945 KGPPGPPGKDGL----------PGHPGQRGETGFQGKTG 973



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 59/192 (30%), Positives = 75/192 (39%), Gaps = 28/192 (14%)

Query: 85   GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRR- 143
            GE GH    G  GE G+P   G       +  +   PG +G  G     G    P +R  
Sbjct: 994  GERGHPGPPGPPGEQGLPGAAG-------KEGAKGDPGPQGISGKDGPAGLRGFPGERGL 1046

Query: 144  -GSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSV 202
             G+  +PG KG  G     G V  P ER     S G  G  G+P R G    P    G  
Sbjct: 1047 PGAQGAPGLKGGEGPQGPPGPVGSPGER----GSAGTAGPIGLPGRPGPQGPP-GPAGEK 1101

Query: 203  ASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPG 262
             +PGEKG  G   R+G        +  V  PG  G  G P  +G        +G +  PG
Sbjct: 1102 GAPGEKGPQGPAGRDGV-------QGPVGLPGPAGPAGSPGEDGD-------KGEIGEPG 1147

Query: 263  EKGECGVRWREG 274
            +KG  G +   G
Sbjct: 1148 QKGSKGDKGENG 1159



 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 58/196 (29%), Positives = 71/196 (36%), Gaps = 54/196 (27%)

Query: 71   PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
            P   P P  LR I G  G     G  G+ G P   G    P         PG KGE G P
Sbjct: 1412 PAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP----GLKGDPGSKGEKGHP 1467

Query: 131  WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
               G +  P ++       GEKG+ G+P  +G             SPG KG+ G+P   G
Sbjct: 1468 GLIGLIGPPGEQ-------GEKGDRGLPGTQG-------------SPGAKGDGGIPGPAG 1507

Query: 191  GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWR 250
                PL   G    PG +G             P   + S    GQKG+ G+P        
Sbjct: 1508 ----PLGPPGPPGLPGPQG-------------PKGNKGSTGPAGQKGDSGLP-------- 1542

Query: 251  PLDRRGSVASPGEKGE 266
                 G   SPG  GE
Sbjct: 1543 -----GPPGSPGPPGE 1553



 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 61/205 (29%), Positives = 79/205 (38%), Gaps = 41/205 (20%)

Query: 75   PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWR--PLERRASVASPGEKGECGVPWR 132
            P P   R   G AG     GEKG  G    EG   +  P+  +     PG +G  G+P  
Sbjct: 1368 PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP 1427

Query: 133  EGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGV 192
             G    P    G    PG  G  G+P  +G              PG KGE G P   G +
Sbjct: 1428 VGEQGLP-GAAGQDGPPGPMGPPGLPGLKG-------------DPGSKGEKGHPGLIGLI 1473

Query: 193  WRPLERR--------GSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWR 244
              P E+         G+  SPG KG+ G+P   G    PL         G  G  G+P  
Sbjct: 1474 GPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAG----PL---------GPPGPPGLPGP 1520

Query: 245  EGAVWRPLDRRGSVASPGEKGECGV 269
            +G    P   +GS    G+KG+ G+
Sbjct: 1521 QG----PKGNKGSTGPAGQKGDSGL 1541



 Score = 62.0 bits (149), Expect = 6e-10
 Identities = 70/225 (31%), Positives = 85/225 (37%), Gaps = 28/225 (12%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAA---GEKGECGIPWTEGQVWRPLER--------RASVA 119
           P   P    L   DG  GH       GEKG  G P  +G +  P  R        R    
Sbjct: 728 PQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKG 787

Query: 120 SPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQ 179
           S GEKGE G P  +G +    D RG V   G +GE G P    G   P          G+
Sbjct: 788 SKGEKGEDGFPGFKGDMGLKGD-RGEVGQIGPRGEDG-PEGPKGRAGPTGDPGPSGQAGE 845

Query: 180 KGECGVPWREGGVWRPLERRGSVASP------GEKGECGVPWREGRVWRPLERRASVASP 233
           KG+ GVP   G   R    +GS   P      GEKG  GV  + G    P  +R      
Sbjct: 846 KGKLGVPGLPGYPGRQ-GPKGSTGFPGFPGANGEKGARGVAGKPG----PRGQRGPTGPR 900

Query: 234 GQKGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREGRVWY 278
           G +G  G   + G    P    G    PG  GE G +  +G V +
Sbjct: 901 GSRGARGPTGKPG----PKGTSGGDGPPGPPGERGPQGPQGPVGF 941



 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 63/222 (28%), Positives = 82/222 (36%), Gaps = 33/222 (14%)

Query: 71   PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWR--------PLERRASVASPG 122
            P   P P     + G  G     G +G+ G P   G V          P+  R     PG
Sbjct: 944  PKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG 1003

Query: 123  EKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGE 182
              GE G+P   G+        G+   PG +G  G     G    P ER      PG +G 
Sbjct: 1004 PPGEQGLPGAAGK-------EGAKGDPGPQGISGKDGPAGLRGFPGER----GLPGAQGA 1052

Query: 183  CGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLER-----RASVASPGQKG 237
             G+   EG    P    G V SPGE+G  G     G   RP  +          +PG+KG
Sbjct: 1053 PGLKGGEGPQGPP----GPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG 1108

Query: 238  ECGVPWREG-----AVWRPLDRRGSVASPGEKGECGVRWREG 274
              G   R+G      +  P    GS    G+KGE G   ++G
Sbjct: 1109 PQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKG 1150



 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 64/212 (30%), Positives = 78/212 (36%), Gaps = 39/212 (18%)

Query: 75   PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
            P PR  R   G  G   A G  G+ G   T G    P         PGE+G         
Sbjct: 888  PGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPP-------GPPGERG--------- 931

Query: 135  RVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLER-----RASVASPGQKGECGVPWRE 189
                P   +G V  PG KG  G P ++G    P +R     +     PG  G  G P   
Sbjct: 932  ----PQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVG-PQGP 986

Query: 190  GGVWRPLERRGSVASPGEKGECGVP---WREGRVWRPLERRAS-----VASPGQKGECGV 241
             G   P+  RG    PG  GE G+P    +EG    P  +  S         G  GE G+
Sbjct: 987  TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL 1046

Query: 242  PWREGAVW-----RPLDRRGSVASPGEKGECG 268
            P  +GA        P    G V SPGE+G  G
Sbjct: 1047 PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAG 1078



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 64/213 (30%), Positives = 80/213 (37%), Gaps = 18/213 (8%)

Query: 74   VPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWRE 133
            V  P+  R   GEAG   AAG  G  G P  +G    P      V  PG+ G  G P   
Sbjct: 1283 VGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP----GPVGFPGDPGPPGEPGPA 1338

Query: 134  GRVWRPLDR-----RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWR 188
            G+     D+      G    PG  GE G P   G    P    A     G+KG  G    
Sbjct: 1339 GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE-GRQGEKGAKGEAGA 1397

Query: 189  EG--GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREG 246
            EG  G   P+  +G    PG +G  G+P   G    P         PG  G  G+P  +G
Sbjct: 1398 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLP-GAAGQDGPPGPMGPPGLPGLKG 1456

Query: 247  AVWRPLDRR-----GSVASPGEKGECGVRWREG 274
                  ++      G +  PGE+GE G R   G
Sbjct: 1457 DPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1489



 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 63/212 (29%), Positives = 82/212 (38%), Gaps = 31/212 (14%)

Query: 68   SAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGEC 127
            +A P  +P     +   G AG   A GEKG  G    +G        +  V  PG  G  
Sbjct: 1079 TAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGV-------QGPVGLPGPAGPA 1131

Query: 128  GVPWREG---RVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECG 184
            G P  +G    +  P  ++GS    GE G  G P  +G V  P         PG +G+ G
Sbjct: 1132 GSPGEDGDKGEIGEP-GQKGSKGDKGENGPPGPPGLQGPVGAP-GIAGGDGEPGPRGQQG 1189

Query: 185  VPWREG--------GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQK 236
            +  ++G        G   P+  +G    PGEKGE G     G    P  R       G +
Sbjct: 1190 MFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR-------GPQ 1242

Query: 237  GECGVPWREGAVWRPLDRRGSVASPGEKGECG 268
            G  G    +G    P    GSV   GEKGE G
Sbjct: 1243 GPNGADGPQG----PPGSVGSVGGVGEKGEPG 1270



 Score = 55.1 bits (131), Expect = 8e-08
 Identities = 64/236 (27%), Positives = 85/236 (36%), Gaps = 40/236 (16%)

Query: 75  PAPRPLRSIDGEAGHSEAAGEKGECGIPWTE---------GQVWRPLERRASVAS----- 120
           P P  L    G  G   ++G KGE G P  +         G   +P +R    A      
Sbjct: 543 PGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGM 602

Query: 121 PGEKGECGVPWREGRVWRPLDR-----RGSVASPGEKGECGVPWREG-----------GV 164
           PGE G  G    +G    P D+     RG    PG  G+ G+   +G           G 
Sbjct: 603 PGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGP 662

Query: 165 WRPLERRASVASPGQKGECGVPWREG--GVWRPLERRGSVASPGEKGECGVPWREGRVWR 222
              L  R +  +PGQ G  GV    G  G   P    G     G  G  G+P  +G +  
Sbjct: 663 RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGP 722

Query: 223 PLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREGRVWY 278
           P E+       G+ G  G+P  +G    P    G     GEKG  G    +G + Y
Sbjct: 723 PGEK----GPQGKPGLAGLPGADGPPGHP----GKEGQSGEKGALGPPGPQGPIGY 770



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 64/221 (28%), Positives = 75/221 (33%), Gaps = 37/221 (16%)

Query: 75   PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
            P PR      G+ G     G++G  G P   G    P+  +     PGEKGE G     G
Sbjct: 1182 PGPR------GQQGMFGQKGDEGARGFPGPPG----PIGLQGLPGPPGEKGENGDVGPMG 1231

Query: 135  RVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWR 194
                P   RG     G  G  G P   G V    E+      PG+ G  G P  E GV  
Sbjct: 1232 PPGPP-GPRGPQGPNGADGPQGPPGSVGSVGGVGEK----GEPGEAGNPGPPG-EAGVGG 1285

Query: 195  PLERRGSVASPGEKGECGVPWREGRVW--RPLERRASVASP------------------G 234
            P   RG     G  G  G P  +G      P      V  P                  G
Sbjct: 1286 PKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGG 1345

Query: 235  QKGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREGR 275
             KGE G P + G    P    G    PG++G  G    EGR
Sbjct: 1346 DKGEDGDPGQPGPP-GPSGEAGPPGPPGKRGPPGAAGAEGR 1385



 Score = 30.0 bits (66), Expect = 2.7
 Identities = 39/168 (23%), Positives = 60/168 (35%), Gaps = 26/168 (15%)

Query: 53  DQMGSVEKLTTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPL 112
           +++ + E LT   + S +  S       + IDG        G+ GE      +    +P 
Sbjct: 347 EEIFTEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKP- 405

Query: 113 ERRASVASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRA 172
                 + P E+   GVP         ++  G+    G+KGE                  
Sbjct: 406 -----TSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGE-----------------P 443

Query: 173 SVASPGQKGECGVPWREG--GVWRPLERRGSVASPGEKGECGVPWREG 218
           +V  PG   E G P   G  G+  P   +G    PG+ G+ G P R G
Sbjct: 444 AVVEPGMLVE-GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPG 490


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
           sapiens]
          Length = 1767

 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 66/219 (30%), Positives = 86/219 (39%), Gaps = 27/219 (12%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
           P   P PR ++  DG  G   + GEKGE G P  +G +    + R  V   G +GE G  
Sbjct: 716 PIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGD-RGEVGQIGPRGEDGPE 774

Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGV--- 185
             +GR   P    G     GEKG+ GVP   G  G   P         PG  GE G    
Sbjct: 775 GPKGRA-GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV 833

Query: 186 -----PWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLER-----RASVASPGQ 235
                P  + G   P   RG+    G+ G  G    +G    P ER     +  V  PG 
Sbjct: 834 AGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP 893

Query: 236 KGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREG 274
           KG  G P ++G              PG++GE G + + G
Sbjct: 894 KGPPGPPGKDGL----------PGHPGQRGETGFQGKTG 922



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 59/192 (30%), Positives = 75/192 (39%), Gaps = 28/192 (14%)

Query: 85   GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRR- 143
            GE GH    G  GE G+P   G       +  +   PG +G  G     G    P +R  
Sbjct: 943  GERGHPGPPGPPGEQGLPGAAG-------KEGAKGDPGPQGISGKDGPAGLRGFPGERGL 995

Query: 144  -GSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSV 202
             G+  +PG KG  G     G V  P ER     S G  G  G+P R G    P    G  
Sbjct: 996  PGAQGAPGLKGGEGPQGPPGPVGSPGER----GSAGTAGPIGLPGRPGPQGPP-GPAGEK 1050

Query: 203  ASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPG 262
             +PGEKG  G   R+G        +  V  PG  G  G P  +G        +G +  PG
Sbjct: 1051 GAPGEKGPQGPAGRDGV-------QGPVGLPGPAGPAGSPGEDGD-------KGEIGEPG 1096

Query: 263  EKGECGVRWREG 274
            +KG  G +   G
Sbjct: 1097 QKGSKGDKGENG 1108



 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 58/196 (29%), Positives = 71/196 (36%), Gaps = 54/196 (27%)

Query: 71   PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
            P   P P  LR I G  G     G  G+ G P   G    P         PG KGE G P
Sbjct: 1361 PAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP----GLKGDPGSKGEKGHP 1416

Query: 131  WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
               G +  P ++       GEKG+ G+P  +G             SPG KG+ G+P   G
Sbjct: 1417 GLIGLIGPPGEQ-------GEKGDRGLPGTQG-------------SPGAKGDGGIPGPAG 1456

Query: 191  GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWR 250
                PL   G    PG +G             P   + S    GQKG+ G+P        
Sbjct: 1457 ----PLGPPGPPGLPGPQG-------------PKGNKGSTGPAGQKGDSGLP-------- 1491

Query: 251  PLDRRGSVASPGEKGE 266
                 G   SPG  GE
Sbjct: 1492 -----GPPGSPGPPGE 1502



 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 61/205 (29%), Positives = 79/205 (38%), Gaps = 41/205 (20%)

Query: 75   PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWR--PLERRASVASPGEKGECGVPWR 132
            P P   R   G AG     GEKG  G    EG   +  P+  +     PG +G  G+P  
Sbjct: 1317 PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP 1376

Query: 133  EGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGV 192
             G    P    G    PG  G  G+P  +G              PG KGE G P   G +
Sbjct: 1377 VGEQGLP-GAAGQDGPPGPMGPPGLPGLKG-------------DPGSKGEKGHPGLIGLI 1422

Query: 193  WRPLERR--------GSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWR 244
              P E+         G+  SPG KG+ G+P   G    PL         G  G  G+P  
Sbjct: 1423 GPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAG----PL---------GPPGPPGLPGP 1469

Query: 245  EGAVWRPLDRRGSVASPGEKGECGV 269
            +G    P   +GS    G+KG+ G+
Sbjct: 1470 QG----PKGNKGSTGPAGQKGDSGL 1490



 Score = 62.0 bits (149), Expect = 6e-10
 Identities = 70/225 (31%), Positives = 85/225 (37%), Gaps = 28/225 (12%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAA---GEKGECGIPWTEGQVWRPLER--------RASVA 119
           P   P    L   DG  GH       GEKG  G P  +G +  P  R        R    
Sbjct: 677 PQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKG 736

Query: 120 SPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQ 179
           S GEKGE G P  +G +    D RG V   G +GE G P    G   P          G+
Sbjct: 737 SKGEKGEDGFPGFKGDMGLKGD-RGEVGQIGPRGEDG-PEGPKGRAGPTGDPGPSGQAGE 794

Query: 180 KGECGVPWREGGVWRPLERRGSVASP------GEKGECGVPWREGRVWRPLERRASVASP 233
           KG+ GVP   G   R    +GS   P      GEKG  GV  + G    P  +R      
Sbjct: 795 KGKLGVPGLPGYPGRQ-GPKGSTGFPGFPGANGEKGARGVAGKPG----PRGQRGPTGPR 849

Query: 234 GQKGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREGRVWY 278
           G +G  G   + G    P    G    PG  GE G +  +G V +
Sbjct: 850 GSRGARGPTGKPG----PKGTSGGDGPPGPPGERGPQGPQGPVGF 890



 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 63/222 (28%), Positives = 82/222 (36%), Gaps = 33/222 (14%)

Query: 71   PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWR--------PLERRASVASPG 122
            P   P P     + G  G     G +G+ G P   G V          P+  R     PG
Sbjct: 893  PKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG 952

Query: 123  EKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGE 182
              GE G+P   G+        G+   PG +G  G     G    P ER      PG +G 
Sbjct: 953  PPGEQGLPGAAGK-------EGAKGDPGPQGISGKDGPAGLRGFPGER----GLPGAQGA 1001

Query: 183  CGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLER-----RASVASPGQKG 237
             G+   EG    P    G V SPGE+G  G     G   RP  +          +PG+KG
Sbjct: 1002 PGLKGGEGPQGPP----GPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG 1057

Query: 238  ECGVPWREG-----AVWRPLDRRGSVASPGEKGECGVRWREG 274
              G   R+G      +  P    GS    G+KGE G   ++G
Sbjct: 1058 PQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKG 1099



 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 64/212 (30%), Positives = 78/212 (36%), Gaps = 39/212 (18%)

Query: 75   PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
            P PR  R   G  G   A G  G+ G   T G    P         PGE+G         
Sbjct: 837  PGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPP-------GPPGERG--------- 880

Query: 135  RVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLER-----RASVASPGQKGECGVPWRE 189
                P   +G V  PG KG  G P ++G    P +R     +     PG  G  G P   
Sbjct: 881  ----PQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVG-PQGP 935

Query: 190  GGVWRPLERRGSVASPGEKGECGVP---WREGRVWRPLERRAS-----VASPGQKGECGV 241
             G   P+  RG    PG  GE G+P    +EG    P  +  S         G  GE G+
Sbjct: 936  TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL 995

Query: 242  PWREGAVW-----RPLDRRGSVASPGEKGECG 268
            P  +GA        P    G V SPGE+G  G
Sbjct: 996  PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAG 1027



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 64/213 (30%), Positives = 80/213 (37%), Gaps = 18/213 (8%)

Query: 74   VPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWRE 133
            V  P+  R   GEAG   AAG  G  G P  +G    P      V  PG+ G  G P   
Sbjct: 1232 VGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP----GPVGFPGDPGPPGEPGPA 1287

Query: 134  GRVWRPLDR-----RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWR 188
            G+     D+      G    PG  GE G P   G    P    A     G+KG  G    
Sbjct: 1288 GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE-GRQGEKGAKGEAGA 1346

Query: 189  EG--GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREG 246
            EG  G   P+  +G    PG +G  G+P   G    P         PG  G  G+P  +G
Sbjct: 1347 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLP-GAAGQDGPPGPMGPPGLPGLKG 1405

Query: 247  AVWRPLDRR-----GSVASPGEKGECGVRWREG 274
                  ++      G +  PGE+GE G R   G
Sbjct: 1406 DPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1438



 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 63/212 (29%), Positives = 82/212 (38%), Gaps = 31/212 (14%)

Query: 68   SAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGEC 127
            +A P  +P     +   G AG   A GEKG  G    +G        +  V  PG  G  
Sbjct: 1028 TAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGV-------QGPVGLPGPAGPA 1080

Query: 128  GVPWREG---RVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECG 184
            G P  +G    +  P  ++GS    GE G  G P  +G V  P         PG +G+ G
Sbjct: 1081 GSPGEDGDKGEIGEP-GQKGSKGDKGENGPPGPPGLQGPVGAP-GIAGGDGEPGPRGQQG 1138

Query: 185  VPWREG--------GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQK 236
            +  ++G        G   P+  +G    PGEKGE G     G    P  R       G +
Sbjct: 1139 MFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR-------GPQ 1191

Query: 237  GECGVPWREGAVWRPLDRRGSVASPGEKGECG 268
            G  G    +G    P    GSV   GEKGE G
Sbjct: 1192 GPNGADGPQG----PPGSVGSVGGVGEKGEPG 1219



 Score = 55.1 bits (131), Expect = 8e-08
 Identities = 64/236 (27%), Positives = 85/236 (36%), Gaps = 40/236 (16%)

Query: 75  PAPRPLRSIDGEAGHSEAAGEKGECGIPWTE---------GQVWRPLERRASVAS----- 120
           P P  L    G  G   ++G KGE G P  +         G   +P +R    A      
Sbjct: 492 PGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGM 551

Query: 121 PGEKGECGVPWREGRVWRPLDR-----RGSVASPGEKGECGVPWREG-----------GV 164
           PGE G  G    +G    P D+     RG    PG  G+ G+   +G           G 
Sbjct: 552 PGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGP 611

Query: 165 WRPLERRASVASPGQKGECGVPWREG--GVWRPLERRGSVASPGEKGECGVPWREGRVWR 222
              L  R +  +PGQ G  GV    G  G   P    G     G  G  G+P  +G +  
Sbjct: 612 RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGP 671

Query: 223 PLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREGRVWY 278
           P E+       G+ G  G+P  +G    P    G     GEKG  G    +G + Y
Sbjct: 672 PGEK----GPQGKPGLAGLPGADGPPGHP----GKEGQSGEKGALGPPGPQGPIGY 719



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 64/221 (28%), Positives = 75/221 (33%), Gaps = 37/221 (16%)

Query: 75   PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
            P PR      G+ G     G++G  G P   G    P+  +     PGEKGE G     G
Sbjct: 1131 PGPR------GQQGMFGQKGDEGARGFPGPPG----PIGLQGLPGPPGEKGENGDVGPMG 1180

Query: 135  RVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWR 194
                P   RG     G  G  G P   G V    E+      PG+ G  G P  E GV  
Sbjct: 1181 PPGPP-GPRGPQGPNGADGPQGPPGSVGSVGGVGEK----GEPGEAGNPGPPG-EAGVGG 1234

Query: 195  PLERRGSVASPGEKGECGVPWREGRVW--RPLERRASVASP------------------G 234
            P   RG     G  G  G P  +G      P      V  P                  G
Sbjct: 1235 PKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGG 1294

Query: 235  QKGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREGR 275
             KGE G P + G    P    G    PG++G  G    EGR
Sbjct: 1295 DKGEDGDPGQPGPP-GPSGEAGPPGPPGKRGPPGAAGAEGR 1334



 Score = 30.0 bits (66), Expect = 2.7
 Identities = 39/168 (23%), Positives = 60/168 (35%), Gaps = 26/168 (15%)

Query: 53  DQMGSVEKLTTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPL 112
           +++ + E LT   + S +  S       + IDG        G+ GE      +    +P 
Sbjct: 296 EEIFTEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKP- 354

Query: 113 ERRASVASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRA 172
                 + P E+   GVP         ++  G+    G+KGE                  
Sbjct: 355 -----TSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGE-----------------P 392

Query: 173 SVASPGQKGECGVPWREG--GVWRPLERRGSVASPGEKGECGVPWREG 218
           +V  PG   E G P   G  G+  P   +G    PG+ G+ G P R G
Sbjct: 393 AVVEPGMLVE-GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPG 439


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
           sapiens]
          Length = 1806

 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 66/219 (30%), Positives = 86/219 (39%), Gaps = 27/219 (12%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
           P   P PR ++  DG  G   + GEKGE G P  +G +    + R  V   G +GE G  
Sbjct: 755 PIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGD-RGEVGQIGPRGEDGPE 813

Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGV--- 185
             +GR   P    G     GEKG+ GVP   G  G   P         PG  GE G    
Sbjct: 814 GPKGRA-GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV 872

Query: 186 -----PWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLER-----RASVASPGQ 235
                P  + G   P   RG+    G+ G  G    +G    P ER     +  V  PG 
Sbjct: 873 AGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP 932

Query: 236 KGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREG 274
           KG  G P ++G              PG++GE G + + G
Sbjct: 933 KGPPGPPGKDGL----------PGHPGQRGETGFQGKTG 961



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 59/192 (30%), Positives = 75/192 (39%), Gaps = 28/192 (14%)

Query: 85   GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRR- 143
            GE GH    G  GE G+P   G       +  +   PG +G  G     G    P +R  
Sbjct: 982  GERGHPGPPGPPGEQGLPGAAG-------KEGAKGDPGPQGISGKDGPAGLRGFPGERGL 1034

Query: 144  -GSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSV 202
             G+  +PG KG  G     G V  P ER     S G  G  G+P R G    P    G  
Sbjct: 1035 PGAQGAPGLKGGEGPQGPPGPVGSPGER----GSAGTAGPIGLPGRPGPQGPP-GPAGEK 1089

Query: 203  ASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPG 262
             +PGEKG  G   R+G        +  V  PG  G  G P  +G        +G +  PG
Sbjct: 1090 GAPGEKGPQGPAGRDGV-------QGPVGLPGPAGPAGSPGEDGD-------KGEIGEPG 1135

Query: 263  EKGECGVRWREG 274
            +KG  G +   G
Sbjct: 1136 QKGSKGDKGENG 1147



 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 58/196 (29%), Positives = 71/196 (36%), Gaps = 54/196 (27%)

Query: 71   PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
            P   P P  LR I G  G     G  G+ G P   G    P         PG KGE G P
Sbjct: 1400 PAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP----GLKGDPGSKGEKGHP 1455

Query: 131  WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
               G +  P ++       GEKG+ G+P  +G             SPG KG+ G+P   G
Sbjct: 1456 GLIGLIGPPGEQ-------GEKGDRGLPGTQG-------------SPGAKGDGGIPGPAG 1495

Query: 191  GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWR 250
                PL   G    PG +G             P   + S    GQKG+ G+P        
Sbjct: 1496 ----PLGPPGPPGLPGPQG-------------PKGNKGSTGPAGQKGDSGLP-------- 1530

Query: 251  PLDRRGSVASPGEKGE 266
                 G   SPG  GE
Sbjct: 1531 -----GPPGSPGPPGE 1541



 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 61/205 (29%), Positives = 79/205 (38%), Gaps = 41/205 (20%)

Query: 75   PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWR--PLERRASVASPGEKGECGVPWR 132
            P P   R   G AG     GEKG  G    EG   +  P+  +     PG +G  G+P  
Sbjct: 1356 PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP 1415

Query: 133  EGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGV 192
             G    P    G    PG  G  G+P  +G              PG KGE G P   G +
Sbjct: 1416 VGEQGLP-GAAGQDGPPGPMGPPGLPGLKG-------------DPGSKGEKGHPGLIGLI 1461

Query: 193  WRPLERR--------GSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWR 244
              P E+         G+  SPG KG+ G+P   G    PL         G  G  G+P  
Sbjct: 1462 GPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAG----PL---------GPPGPPGLPGP 1508

Query: 245  EGAVWRPLDRRGSVASPGEKGECGV 269
            +G    P   +GS    G+KG+ G+
Sbjct: 1509 QG----PKGNKGSTGPAGQKGDSGL 1529



 Score = 62.0 bits (149), Expect = 6e-10
 Identities = 70/225 (31%), Positives = 85/225 (37%), Gaps = 28/225 (12%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAA---GEKGECGIPWTEGQVWRPLER--------RASVA 119
           P   P    L   DG  GH       GEKG  G P  +G +  P  R        R    
Sbjct: 716 PQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKG 775

Query: 120 SPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQ 179
           S GEKGE G P  +G +    D RG V   G +GE G P    G   P          G+
Sbjct: 776 SKGEKGEDGFPGFKGDMGLKGD-RGEVGQIGPRGEDG-PEGPKGRAGPTGDPGPSGQAGE 833

Query: 180 KGECGVPWREGGVWRPLERRGSVASP------GEKGECGVPWREGRVWRPLERRASVASP 233
           KG+ GVP   G   R    +GS   P      GEKG  GV  + G    P  +R      
Sbjct: 834 KGKLGVPGLPGYPGRQ-GPKGSTGFPGFPGANGEKGARGVAGKPG----PRGQRGPTGPR 888

Query: 234 GQKGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREGRVWY 278
           G +G  G   + G    P    G    PG  GE G +  +G V +
Sbjct: 889 GSRGARGPTGKPG----PKGTSGGDGPPGPPGERGPQGPQGPVGF 929



 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 63/222 (28%), Positives = 82/222 (36%), Gaps = 33/222 (14%)

Query: 71   PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWR--------PLERRASVASPG 122
            P   P P     + G  G     G +G+ G P   G V          P+  R     PG
Sbjct: 932  PKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG 991

Query: 123  EKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGE 182
              GE G+P   G+        G+   PG +G  G     G    P ER      PG +G 
Sbjct: 992  PPGEQGLPGAAGK-------EGAKGDPGPQGISGKDGPAGLRGFPGER----GLPGAQGA 1040

Query: 183  CGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLER-----RASVASPGQKG 237
             G+   EG    P    G V SPGE+G  G     G   RP  +          +PG+KG
Sbjct: 1041 PGLKGGEGPQGPP----GPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG 1096

Query: 238  ECGVPWREG-----AVWRPLDRRGSVASPGEKGECGVRWREG 274
              G   R+G      +  P    GS    G+KGE G   ++G
Sbjct: 1097 PQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKG 1138



 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 64/212 (30%), Positives = 78/212 (36%), Gaps = 39/212 (18%)

Query: 75   PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
            P PR  R   G  G   A G  G+ G   T G    P         PGE+G         
Sbjct: 876  PGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPP-------GPPGERG--------- 919

Query: 135  RVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLER-----RASVASPGQKGECGVPWRE 189
                P   +G V  PG KG  G P ++G    P +R     +     PG  G  G P   
Sbjct: 920  ----PQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVG-PQGP 974

Query: 190  GGVWRPLERRGSVASPGEKGECGVP---WREGRVWRPLERRAS-----VASPGQKGECGV 241
             G   P+  RG    PG  GE G+P    +EG    P  +  S         G  GE G+
Sbjct: 975  TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL 1034

Query: 242  PWREGAVW-----RPLDRRGSVASPGEKGECG 268
            P  +GA        P    G V SPGE+G  G
Sbjct: 1035 PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAG 1066



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 64/213 (30%), Positives = 80/213 (37%), Gaps = 18/213 (8%)

Query: 74   VPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWRE 133
            V  P+  R   GEAG   AAG  G  G P  +G    P      V  PG+ G  G P   
Sbjct: 1271 VGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP----GPVGFPGDPGPPGEPGPA 1326

Query: 134  GRVWRPLDR-----RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWR 188
            G+     D+      G    PG  GE G P   G    P    A     G+KG  G    
Sbjct: 1327 GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE-GRQGEKGAKGEAGA 1385

Query: 189  EG--GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREG 246
            EG  G   P+  +G    PG +G  G+P   G    P         PG  G  G+P  +G
Sbjct: 1386 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLP-GAAGQDGPPGPMGPPGLPGLKG 1444

Query: 247  AVWRPLDRR-----GSVASPGEKGECGVRWREG 274
                  ++      G +  PGE+GE G R   G
Sbjct: 1445 DPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1477



 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 63/212 (29%), Positives = 82/212 (38%), Gaps = 31/212 (14%)

Query: 68   SAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGEC 127
            +A P  +P     +   G AG   A GEKG  G    +G        +  V  PG  G  
Sbjct: 1067 TAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGV-------QGPVGLPGPAGPA 1119

Query: 128  GVPWREG---RVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECG 184
            G P  +G    +  P  ++GS    GE G  G P  +G V  P         PG +G+ G
Sbjct: 1120 GSPGEDGDKGEIGEP-GQKGSKGDKGENGPPGPPGLQGPVGAP-GIAGGDGEPGPRGQQG 1177

Query: 185  VPWREG--------GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQK 236
            +  ++G        G   P+  +G    PGEKGE G     G    P  R       G +
Sbjct: 1178 MFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR-------GPQ 1230

Query: 237  GECGVPWREGAVWRPLDRRGSVASPGEKGECG 268
            G  G    +G    P    GSV   GEKGE G
Sbjct: 1231 GPNGADGPQG----PPGSVGSVGGVGEKGEPG 1258



 Score = 55.1 bits (131), Expect = 8e-08
 Identities = 64/236 (27%), Positives = 85/236 (36%), Gaps = 40/236 (16%)

Query: 75  PAPRPLRSIDGEAGHSEAAGEKGECGIPWTE---------GQVWRPLERRASVAS----- 120
           P P  L    G  G   ++G KGE G P  +         G   +P +R    A      
Sbjct: 531 PGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGM 590

Query: 121 PGEKGECGVPWREGRVWRPLDR-----RGSVASPGEKGECGVPWREG-----------GV 164
           PGE G  G    +G    P D+     RG    PG  G+ G+   +G           G 
Sbjct: 591 PGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGP 650

Query: 165 WRPLERRASVASPGQKGECGVPWREG--GVWRPLERRGSVASPGEKGECGVPWREGRVWR 222
              L  R +  +PGQ G  GV    G  G   P    G     G  G  G+P  +G +  
Sbjct: 651 RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGP 710

Query: 223 PLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREGRVWY 278
           P E+       G+ G  G+P  +G    P    G     GEKG  G    +G + Y
Sbjct: 711 PGEK----GPQGKPGLAGLPGADGPPGHP----GKEGQSGEKGALGPPGPQGPIGY 758



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 64/221 (28%), Positives = 75/221 (33%), Gaps = 37/221 (16%)

Query: 75   PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
            P PR      G+ G     G++G  G P   G    P+  +     PGEKGE G     G
Sbjct: 1170 PGPR------GQQGMFGQKGDEGARGFPGPPG----PIGLQGLPGPPGEKGENGDVGPMG 1219

Query: 135  RVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWR 194
                P   RG     G  G  G P   G V    E+      PG+ G  G P  E GV  
Sbjct: 1220 PPGPP-GPRGPQGPNGADGPQGPPGSVGSVGGVGEK----GEPGEAGNPGPPG-EAGVGG 1273

Query: 195  PLERRGSVASPGEKGECGVPWREGRVW--RPLERRASVASP------------------G 234
            P   RG     G  G  G P  +G      P      V  P                  G
Sbjct: 1274 PKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGG 1333

Query: 235  QKGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREGR 275
             KGE G P + G    P    G    PG++G  G    EGR
Sbjct: 1334 DKGEDGDPGQPGPP-GPSGEAGPPGPPGKRGPPGAAGAEGR 1373



 Score = 30.0 bits (66), Expect = 2.7
 Identities = 39/168 (23%), Positives = 60/168 (35%), Gaps = 26/168 (15%)

Query: 53  DQMGSVEKLTTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPL 112
           +++ + E LT   + S +  S       + IDG        G+ GE      +    +P 
Sbjct: 335 EEIFTEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKP- 393

Query: 113 ERRASVASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRA 172
                 + P E+   GVP         ++  G+    G+KGE                  
Sbjct: 394 -----TSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGE-----------------P 431

Query: 173 SVASPGQKGECGVPWREG--GVWRPLERRGSVASPGEKGECGVPWREG 218
           +V  PG   E G P   G  G+  P   +G    PG+ G+ G P R G
Sbjct: 432 AVVEPGMLVE-GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPG 478


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 65/204 (31%), Positives = 82/204 (40%), Gaps = 23/204 (11%)

Query: 74  VPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWRE 133
           +P    LR   GE G +   GEKGE G+P   G        R      GEKGE G+P  +
Sbjct: 778 LPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFP----GVRGEKGDQGEKGELGLPGLK 833

Query: 134 GRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASP-GQKGECGVPWREGGV 192
           G        RG     G  G  G+P     ++ P  R      P G+KG+ G+P   G  
Sbjct: 834 G-------DRGEKGEAGPAGPPGLPGTT-SLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQ 885

Query: 193 WRP--LERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWR 250
            RP  L  +G    PG KG+ G     G    P        +PG  G  G     G+V  
Sbjct: 886 GRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNP-------GAPGHVGAPGPSGPPGSVGA 938

Query: 251 PLDRRGSVASPGEKGECGVRWREG 274
           P   RG+    GE+GE G    EG
Sbjct: 939 P-GLRGTPGKDGERGEKGAAGEEG 961



 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 74/238 (31%), Positives = 95/238 (39%), Gaps = 43/238 (18%)

Query: 67  LSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGI------PWTEGQVWRPLERRASVAS 120
           L   PG V AP     + GE G     GEKGE G+      P   GQ  RP    + VA 
Sbjct: 576 LPGPPGRVGAP----GLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRP--GPSGVAG 629

Query: 121 P-GEKGE---CGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVAS 176
           P GEKG+    G P   G V +    +G   +PG +G  G P    G   P+        
Sbjct: 630 PQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAP-GPPGARGPIGPEGRDGP 688

Query: 177 P------GQKGECGVPWREG-----------GVWRPLERRGSVASPGEKGECGVPWREGR 219
           P      G+KG+ G P   G           GV  P    GS   PGE G  G P   G 
Sbjct: 689 PGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGP 748

Query: 220 VWRPLE--------RRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECGV 269
              P +           +   PG++GE G+P + G +   +  +G    PGEKGE G+
Sbjct: 749 TGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPG-LRGEIGEQGLAGRPGEKGEAGL 805



 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 69/233 (29%), Positives = 92/233 (39%), Gaps = 47/233 (20%)

Query: 68   SAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRP--LERRASVASPGEKG 125
            S  PG +P        DG+ G     G+ GE G+P  EG    P          +PG +G
Sbjct: 1233 SGLPG-IPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRG 1291

Query: 126  ECG---VPWREGRVWR-----------------PLDRRGSVASPGEKGECGVPWREG--- 162
            E G   +P +EG   +                 P  + GS  SPGE G  G P ++G   
Sbjct: 1292 ESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKG 1351

Query: 163  -----GVWRPLERRASVASPGQKGECGVPWREGGVWRPLER--RGSVASPGEKGECGVPW 215
                 G+   L  R     PG+ GE GVP +EG   +P E   +G    PG KG+ G P 
Sbjct: 1352 ENGSPGLPGFLGPR---GPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPG 1408

Query: 216  REGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECG 268
             +G+   P         PG KG  G+   +G         G V  PG  G+ G
Sbjct: 1409 GKGQPGDP-------GIPGHKGHTGLMGPQGLP----GENGPVGPPGPPGQPG 1450



 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 70/237 (29%), Positives = 98/237 (41%), Gaps = 48/237 (20%)

Query: 50  PREDQMGSVEKLTTSAFLSAK-------PGSVPAPRPLRSIDGEAGHSEAAGEKGECGI- 101
           P  +Q+G ++ +  S     K       P  +P P+      G  G     GEKG+ GI 
Sbjct: 463 PGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIG 522

Query: 102 PWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWRE 161
           P+ +G+              GEKG  G+P   GR       +G    PGE GE G+P  E
Sbjct: 523 PFGQGE-------------KGEKGSLGLPGPPGRD----GSKGMRGEPGELGEPGLP-GE 564

Query: 162 GGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVASPGEKGECGV------PW 215
            G+  P   +     PG  G  G P  +G        RG   + GEKGE G+      P 
Sbjct: 565 VGMRGP---QGPPGLPGPPGRVGAPGLQG-------ERGEKGTRGEKGERGLDGFPGKPG 614

Query: 216 REGRVWRPLERRASVASP-GQKGE---CGVPWREGAVWRPLDRRGSVASPGEKGECG 268
             G+  RP    + VA P G+KG+    G P   G+V +    +G   +PG +G  G
Sbjct: 615 DTGQQGRP--GPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQG 669



 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 65/218 (29%), Positives = 85/218 (38%), Gaps = 37/218 (16%)

Query: 85  GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
           G AG     G+ G  G P   G V +    +    +PG +G  G P   G    P+   G
Sbjct: 626 GVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPG-ARGPIGPEG 684

Query: 145 SVASP------GEKGECGVPWREG-----------GVWRPLERRASVASPGQKGECGVPW 187
               P      G+KG+ G P   G           GV  P        SPG  GE G P 
Sbjct: 685 RDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGP---PGPGGSPGLPGEIGFPG 741

Query: 188 REG-----------GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQK 236
           + G           G   P    G+   PGE+GE G+P + G +   +  +     PG+K
Sbjct: 742 KPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPG-LRGEIGEQGLAGRPGEK 800

Query: 237 GECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREG 274
           GE G+P   GA   P   RG     GEKGE G+   +G
Sbjct: 801 GEAGLP---GAPGFP-GVRGEKGDQGEKGELGLPGLKG 834



 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 62/205 (30%), Positives = 81/205 (39%), Gaps = 44/205 (21%)

Query: 77   PRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRV 136
            P  ++   G+ G     G  G  GIP  EG+  R   +      PG+ GE G+P  EG  
Sbjct: 1214 PPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRD-GKPGPPGEPGKAGEPGLPGPEGAR 1272

Query: 137  WRP--LDRRGSVASPGEKGECG---VPWREGGVWRPLERRASVASPGQKGECGVPWREG- 190
              P      G   +PG +GE G   +P +EG              PG+ G+ G    +G 
Sbjct: 1273 GPPGFKGHTGDSGAPGPRGESGAMGLPGQEG-------------LPGKDGDTGPTGPQGP 1319

Query: 191  -GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVW 249
             G   P  + GS  SPGE G  G P ++G                 KGE G P   G + 
Sbjct: 1320 QGPRGPPGKNGSPGSPGEPGPSGTPGQKG----------------SKGENGSPGLPGFL- 1362

Query: 250  RPLDRRGSVASPGEKGECGVRWREG 274
                  G    PGE GE GV  +EG
Sbjct: 1363 ------GPRGPPGEPGEKGVPGKEG 1381



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 61/208 (29%), Positives = 81/208 (38%), Gaps = 34/208 (16%)

Query: 71   PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASP-GEKGECGV 129
            PG +P  +  + + G+ G     G+KGE G P   G           +A P G +GE G 
Sbjct: 1125 PG-LPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGP--------PGIAGPQGSQGERGA 1175

Query: 130  PWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWRE 189
                G       ++G    PG  G  G P   G    P        + G  G  G P +E
Sbjct: 1176 DGEVG-------QKGDQGHPGVPGFMGPPGNPG----PPGADGIAGAAGPPGIQGSPGKE 1224

Query: 190  GGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVW 249
            G    P   +G    PG  GE G   R+G+   P E       PG+ GE G+P  EGA  
Sbjct: 1225 G----PPGPQGPSGLPGIPGEEGKEGRDGKPGPPGE-------PGKAGEPGLPGPEGARG 1273

Query: 250  RP--LDRRGSVASPGEKGECGVRWREGR 275
             P      G   +PG +GE G     G+
Sbjct: 1274 PPGFKGHTGDSGAPGPRGESGAMGLPGQ 1301



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 66/229 (28%), Positives = 86/229 (37%), Gaps = 33/229 (14%)

Query: 68   SAKPGSVPAP--RPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRP----LERRASVASP 121
            S  PGSV AP  R     DGE G   AAGE+G  G     G    P       +     P
Sbjct: 930  SGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEP 989

Query: 122  GEKGECGVPWREGRVWRPLDRRGS-------VASPGEKGECGVPWREG----------GV 164
            G +G  G+P   G        RGS           G++G  G+P   G          G 
Sbjct: 990  GLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGP 1049

Query: 165  WRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVP-----WREGR 219
              P        SPG +G  G P  +G    P  R G+  +PGE+G  G P        G 
Sbjct: 1050 PGPSGPPGDKGSPGSRGLPGFPGPQG----PAGRDGAPGNPGERGPPGKPGLSSLLSPGD 1105

Query: 220  VWRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECG 268
            +    +   +   PG  G  G+P  +G    P  + G   + G+KGE G
Sbjct: 1106 INLLAKDVCNDCPPGPPGLPGLPGFKGDKGVP-GKPGREGTEGKKGEAG 1153



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 53/183 (28%), Positives = 67/183 (36%), Gaps = 61/183 (33%)

Query: 93  AGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRGSVASPGEK 152
           AGEKGE G+    G              PG KG+ G           +   G+    GEK
Sbjct: 480 AGEKGEMGVAGPMGL-------------PGPKGDIGA----------IGPVGAPGPKGEK 516

Query: 153 GECGV-PWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVASPGEKGEC 211
           G+ G+ P+ +G               G+KG  G+P   G       R GS    GE GE 
Sbjct: 517 GDVGIGPFGQG-------------EKGEKGSLGLPGPPG-------RDGSKGMRGEPGEL 556

Query: 212 GVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRW 271
           G P   G V             G +G  G P   G    P  R G+    GE+GE G R 
Sbjct: 557 GEPGLPGEV-------------GMRGPQGPPGLPG----PPGRVGAPGLQGERGEKGTRG 599

Query: 272 REG 274
            +G
Sbjct: 600 EKG 602



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 55/228 (24%), Positives = 77/228 (33%), Gaps = 65/228 (28%)

Query: 83   IDGEAGHSEAAGEKGECGIPWTEGQVWR------PLERRASVASPGEKGECGVPWREGR- 135
            I G+ G     G+ G+ GIP  +G          P E    V  PG  G+ G P   G  
Sbjct: 1400 IKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGEN-GPVGPPGPPGQPGFPGLRGES 1458

Query: 136  -------------VWRPLDRR-----------------GSVASPGEKGECGVPWREGGVW 165
                         + + L+ R                 G    PG  G+ G+P R G   
Sbjct: 1459 PSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAG--- 1515

Query: 166  RPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVASPGE-----KGECGVPWREGRV 220
                    +  PG+ G+ G+    G +  P   RG+   PG      +GE G P   G+ 
Sbjct: 1516 -------PMGEPGRPGQGGLEGPSGPI-GPKGERGAKGDPGAPGVGLRGEMGPPGIPGQP 1567

Query: 221  WRPLERRASVAS-PGQKGECGVPWREGAVWRPLDRRGSVASPGEKGEC 267
              P   +  +   PG +GE G          P    G    PG  G+C
Sbjct: 1568 GEPGYAKDGLPGIPGPQGETG----------PAGHPGLPGPPGPPGQC 1605


>gi|5803080 macrophage receptor with collagenous structure [Homo
           sapiens]
          Length = 520

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 77/284 (27%), Positives = 112/284 (39%), Gaps = 57/284 (20%)

Query: 29  SSHGGDSDKDLCARTQIYGAQPREDQMGSVEKLTTSAFLSAKPGSVPAPRPLRSIDGEAG 88
           S+H G+      +R Q+  AQ    ++     L      +  PG       +  I GE G
Sbjct: 99  SAHPGEHLAQGASRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPG-------MFRIKGEQG 151

Query: 89  HSEAAGEKGECGIPWTEGQVWRPLERRASVA--------------SPGEKGECGVPWREG 134
                G KG  G+P   G    P E+ A  A               PG KGE G+   +G
Sbjct: 152 APGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAGLQGPQG 211

Query: 135 RVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG---- 190
                  ++G+  +PG +GE G    +GG+  P   +    + G+KG+ G+P  +G    
Sbjct: 212 AP----GKQGATGTPGPQGEKGSK-GDGGLIGP---KGETGTKGEKGDLGLPGSKGDRGM 263

Query: 191 ----GVWRPLERRGS------------VASPGEKGECGVPWREGRVWRPLERRASVASPG 234
               GV  P   +GS               PG KG+ G P  +G    P     +V  PG
Sbjct: 264 KGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPP----GAVGHPG 319

Query: 235 QKGE---CGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREGR 275
            KGE    G P R G    P    G+    G KG+ G++ ++GR
Sbjct: 320 AKGEPGSAGSPGRAGLPGSP-GSPGATGLKGSKGDTGLQGQQGR 362



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 62/214 (28%), Positives = 81/214 (37%), Gaps = 52/214 (24%)

Query: 85  GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASP----GEKGECGVPWREGRVWRPL 140
           G  G +   GEKG+ G+P ++G   R ++  A V  P    G KG+ G P   G    P 
Sbjct: 238 GPKGETGTKGEKGDLGLPGSKGD--RGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPG 295

Query: 141 DRR--------------GSVASPGEKGE---CGVPWREGGVWRPLERRASVASPGQKGEC 183
            +               G+V  PG KGE    G P R G    P    A+    G KG+ 
Sbjct: 296 AKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGAT-GLKGSKGDT 354

Query: 184 GVPWREG-----GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGE 238
           G+  ++G     GV  P   +G   SPG  G  G P                   GQKG+
Sbjct: 355 GLQGQQGRKGESGVPGPAGVKGEQGSPGLAGPKGAP----------------GQAGQKGD 398

Query: 239 CGVPWREGAVWRPLDRRGSVASPGEKGECGVRWR 272
            GV    G        +G     GE+GE  V  R
Sbjct: 399 QGVKGSSG-------EQGVKGEKGERGENSVSVR 425



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 30/98 (30%), Positives = 38/98 (38%), Gaps = 15/98 (15%)

Query: 65  AFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEK 124
           A L   PGS P    L+   G+ G     G KGE G+P   G        +    SPG  
Sbjct: 333 AGLPGSPGS-PGATGLKGSKGDTGLQGQQGRKGESGVPGPAGV-------KGEQGSPGLA 384

Query: 125 GECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREG 162
           G  G P + G       ++G     G  GE GV   +G
Sbjct: 385 GPKGAPGQAG-------QKGDQGVKGSSGEQGVKGEKG 415


>gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [Homo
           sapiens]
          Length = 828

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 76/249 (30%), Positives = 97/249 (38%), Gaps = 49/249 (19%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIP---WTEGQVWR----------------- 110
           P   P P+ +    GE G   A G KG  G+     T+GQ  +                 
Sbjct: 293 PIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRG 352

Query: 111 PLERRASVASPGEKGE---CGVPWREGRVWRPLD-----------RRGSVASPGEKGECG 156
           P        SPGE+G+    G P R GR   P +             G+  SPG KG  G
Sbjct: 353 PDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKG 412

Query: 157 VPWREGGVWRPLER-----RASVASPGQKGECGVPWREGGVWRPLERRGSVASPGEKGEC 211
            P   G    P  R     + S  S G KGE G P  EG    P    G V + G KG+ 
Sbjct: 413 GPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEG----PRGLAGEVGNKGAKGDR 468

Query: 212 GVP---WREGRVWRPLER--RASVASPGQKGECGVPWREGAVWRP-LDRRGSVASPGEKG 265
           G+P     +G +  P ++  R      G +G+ G P  +G   RP     G   +PGEKG
Sbjct: 469 GLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKG 528

Query: 266 ECGVRWREG 274
           E G R  EG
Sbjct: 529 EPGPRGPEG 537



 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 64/209 (30%), Positives = 82/209 (39%), Gaps = 32/209 (15%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLER-----RASVASPGEKG 125
           PG + A +  +   G +G   + G KG  G P   G    P  R     + S  S G KG
Sbjct: 384 PGEIGA-KGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKG 442

Query: 126 ECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQ---K 180
           E G P  EG    P    G V + G KG+ G+P   G  G      ++ S   PG    +
Sbjct: 443 EKGDPGPEG----PRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPR 498

Query: 181 GECGVPWREGGVWRP-LERRGSVASPGEKGECGV---------------PWREGRVWRPL 224
           G+ G P  +G   RP     G   +PGEKGE G                P R+G    P 
Sbjct: 499 GDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPA 558

Query: 225 ERRASVASPGQKGECGVPWREGAVWRPLD 253
           +       PG +G  GVP  EG    P D
Sbjct: 559 DP-GPPGEPGPRGPRGVPGPEGEPGPPGD 586



 Score = 58.9 bits (141), Expect = 5e-09
 Identities = 49/147 (33%), Positives = 63/147 (42%), Gaps = 8/147 (5%)

Query: 75  PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLER--RASVASPGEKGECGVPWR 132
           P P   R + GE G+  A G++G  G    +G +  P ++  R      G +G+ G P  
Sbjct: 447 PGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGP 506

Query: 133 EGRVWRP-LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGG 191
           +G   RP     G   +PGEKGE G    EGG             PG+KGE G P   G 
Sbjct: 507 KGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGG----RGDFGLKGEPGRKGEKGEPADPGP 562

Query: 192 VWRPLERRGSVASPGEKGECGVPWREG 218
              P   RG    PG +GE G P   G
Sbjct: 563 PGEP-GPRGPRGVPGPEGEPGPPGDPG 588



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 44/155 (28%), Positives = 58/155 (37%), Gaps = 32/155 (20%)

Query: 121 PGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQK 180
           PG  G  G   ++G         G    PG+KG  G P  EG +  P         PG K
Sbjct: 255 PGPSGPKGYRGQKGAK----GNMGEPGEPGQKGRQGDPGIEGPIGFP----GPKGVPGFK 306

Query: 181 GECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECG 240
           GE G    +G       R+G+    G+ G  G   + GR+  P         PG +G  G
Sbjct: 307 GEKGEFGADG-------RKGAPGLAGKNGTDGQKGKLGRIGPP----GCKGDPGNRGPDG 355

Query: 241 VPWREGAVWRPLDRRGSVASPGEKGECGVRWREGR 275
            P             G   SPGE+G+ G +   GR
Sbjct: 356 YP-------------GEAGSPGERGDQGGKGDPGR 377


>gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Homo
           sapiens]
          Length = 918

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 76/249 (30%), Positives = 97/249 (38%), Gaps = 49/249 (19%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIP---WTEGQVWR----------------- 110
           P   P P+ +    GE G   A G KG  G+     T+GQ  +                 
Sbjct: 293 PIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRG 352

Query: 111 PLERRASVASPGEKGE---CGVPWREGRVWRPLD-----------RRGSVASPGEKGECG 156
           P        SPGE+G+    G P R GR   P +             G+  SPG KG  G
Sbjct: 353 PDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKG 412

Query: 157 VPWREGGVWRPLER-----RASVASPGQKGECGVPWREGGVWRPLERRGSVASPGEKGEC 211
            P   G    P  R     + S  S G KGE G P  EG    P    G V + G KG+ 
Sbjct: 413 GPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEG----PRGLAGEVGNKGAKGDR 468

Query: 212 GVP---WREGRVWRPLER--RASVASPGQKGECGVPWREGAVWRP-LDRRGSVASPGEKG 265
           G+P     +G +  P ++  R      G +G+ G P  +G   RP     G   +PGEKG
Sbjct: 469 GLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKG 528

Query: 266 ECGVRWREG 274
           E G R  EG
Sbjct: 529 EPGPRGPEG 537



 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 64/209 (30%), Positives = 82/209 (39%), Gaps = 32/209 (15%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLER-----RASVASPGEKG 125
           PG + A +  +   G +G   + G KG  G P   G    P  R     + S  S G KG
Sbjct: 384 PGEIGA-KGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKG 442

Query: 126 ECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQ---K 180
           E G P  EG    P    G V + G KG+ G+P   G  G      ++ S   PG    +
Sbjct: 443 EKGDPGPEG----PRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPR 498

Query: 181 GECGVPWREGGVWRP-LERRGSVASPGEKGECGV---------------PWREGRVWRPL 224
           G+ G P  +G   RP     G   +PGEKGE G                P R+G    P 
Sbjct: 499 GDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPA 558

Query: 225 ERRASVASPGQKGECGVPWREGAVWRPLD 253
           +       PG +G  GVP  EG    P D
Sbjct: 559 DP-GPPGEPGPRGPRGVPGPEGEPGPPGD 586



 Score = 58.9 bits (141), Expect = 5e-09
 Identities = 49/147 (33%), Positives = 63/147 (42%), Gaps = 8/147 (5%)

Query: 75  PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLER--RASVASPGEKGECGVPWR 132
           P P   R + GE G+  A G++G  G    +G +  P ++  R      G +G+ G P  
Sbjct: 447 PGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGP 506

Query: 133 EGRVWRP-LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGG 191
           +G   RP     G   +PGEKGE G    EGG             PG+KGE G P   G 
Sbjct: 507 KGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGG----RGDFGLKGEPGRKGEKGEPADPGP 562

Query: 192 VWRPLERRGSVASPGEKGECGVPWREG 218
              P   RG    PG +GE G P   G
Sbjct: 563 PGEP-GPRGPRGVPGPEGEPGPPGDPG 588



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 44/155 (28%), Positives = 58/155 (37%), Gaps = 32/155 (20%)

Query: 121 PGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQK 180
           PG  G  G   ++G         G    PG+KG  G P  EG +  P         PG K
Sbjct: 255 PGPSGPKGYRGQKGAK----GNMGEPGEPGQKGRQGDPGIEGPIGFP----GPKGVPGFK 306

Query: 181 GECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECG 240
           GE G    +G       R+G+    G+ G  G   + GR+  P         PG +G  G
Sbjct: 307 GEKGEFGADG-------RKGAPGLAGKNGTDGQKGKLGRIGPP----GCKGDPGNRGPDG 355

Query: 241 VPWREGAVWRPLDRRGSVASPGEKGECGVRWREGR 275
            P             G   SPGE+G+ G +   GR
Sbjct: 356 YP-------------GEAGSPGERGDQGGKGDPGR 377


>gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Homo
           sapiens]
          Length = 1019

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 76/249 (30%), Positives = 97/249 (38%), Gaps = 49/249 (19%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIP---WTEGQVWR----------------- 110
           P   P P+ +    GE G   A G KG  G+     T+GQ  +                 
Sbjct: 293 PIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRG 352

Query: 111 PLERRASVASPGEKGE---CGVPWREGRVWRPLD-----------RRGSVASPGEKGECG 156
           P        SPGE+G+    G P R GR   P +             G+  SPG KG  G
Sbjct: 353 PDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKG 412

Query: 157 VPWREGGVWRPLER-----RASVASPGQKGECGVPWREGGVWRPLERRGSVASPGEKGEC 211
            P   G    P  R     + S  S G KGE G P  EG    P    G V + G KG+ 
Sbjct: 413 GPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEG----PRGLAGEVGNKGAKGDR 468

Query: 212 GVP---WREGRVWRPLER--RASVASPGQKGECGVPWREGAVWRP-LDRRGSVASPGEKG 265
           G+P     +G +  P ++  R      G +G+ G P  +G   RP     G   +PGEKG
Sbjct: 469 GLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKG 528

Query: 266 ECGVRWREG 274
           E G R  EG
Sbjct: 529 EPGPRGPEG 537



 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 64/209 (30%), Positives = 82/209 (39%), Gaps = 32/209 (15%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLER-----RASVASPGEKG 125
           PG + A +  +   G +G   + G KG  G P   G    P  R     + S  S G KG
Sbjct: 384 PGEIGA-KGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKG 442

Query: 126 ECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQ---K 180
           E G P  EG    P    G V + G KG+ G+P   G  G      ++ S   PG    +
Sbjct: 443 EKGDPGPEG----PRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPR 498

Query: 181 GECGVPWREGGVWRP-LERRGSVASPGEKGECGV---------------PWREGRVWRPL 224
           G+ G P  +G   RP     G   +PGEKGE G                P R+G    P 
Sbjct: 499 GDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPA 558

Query: 225 ERRASVASPGQKGECGVPWREGAVWRPLD 253
           +       PG +G  GVP  EG    P D
Sbjct: 559 DP-GPPGEPGPRGPRGVPGPEGEPGPPGD 586



 Score = 58.9 bits (141), Expect = 5e-09
 Identities = 49/147 (33%), Positives = 63/147 (42%), Gaps = 8/147 (5%)

Query: 75  PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLER--RASVASPGEKGECGVPWR 132
           P P   R + GE G+  A G++G  G    +G +  P ++  R      G +G+ G P  
Sbjct: 447 PGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGP 506

Query: 133 EGRVWRP-LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGG 191
           +G   RP     G   +PGEKGE G    EGG             PG+KGE G P   G 
Sbjct: 507 KGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGG----RGDFGLKGEPGRKGEKGEPADPGP 562

Query: 192 VWRPLERRGSVASPGEKGECGVPWREG 218
              P   RG    PG +GE G P   G
Sbjct: 563 PGEP-GPRGPRGVPGPEGEPGPPGDPG 588



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 44/155 (28%), Positives = 58/155 (37%), Gaps = 32/155 (20%)

Query: 121 PGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQK 180
           PG  G  G   ++G         G    PG+KG  G P  EG +  P         PG K
Sbjct: 255 PGPSGPKGYRGQKGAK----GNMGEPGEPGQKGRQGDPGIEGPIGFP----GPKGVPGFK 306

Query: 181 GECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECG 240
           GE G    +G       R+G+    G+ G  G   + GR+  P         PG +G  G
Sbjct: 307 GEKGEFGADG-------RKGAPGLAGKNGTDGQKGKLGRIGPP----GCKGDPGNRGPDG 355

Query: 241 VPWREGAVWRPLDRRGSVASPGEKGECGVRWREGR 275
            P             G   SPGE+G+ G +   GR
Sbjct: 356 YP-------------GEAGSPGERGDQGGKGDPGR 377


>gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]
          Length = 957

 Score = 69.3 bits (168), Expect = 4e-12
 Identities = 72/265 (27%), Positives = 102/265 (38%), Gaps = 50/265 (18%)

Query: 46  YGAQPREDQMGSVEKLTTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTE 105
           Y  QP +D     + +  +  +   PG +   R L    GE G     G+KG+ G+P   
Sbjct: 468 YPGQPGQDGKPGYQGIAGTPGVPGSPG-IQGARGLPGYKGEPGRD---GDKGDRGLPGFP 523

Query: 106 GQVWRP-----LERRASVASP---------GEKGECGVPWREGRVWRP--LDRRGSVASP 149
           G    P     +  +    SP         GEKG  G P   G    P    + G + SP
Sbjct: 524 GLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSP 583

Query: 150 GEKGEC---GVPWREGGVWRP-----------LERRASVASPGQKGECGVPWREG----- 190
           G KGE    G P ++G    P           + ++  +  PGQ+G+ G P   G     
Sbjct: 584 GFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSN 643

Query: 191 GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWR 250
           G        GS  S GE G  G+P   G    P     +  SPG+ G  G+P  +G    
Sbjct: 644 GSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEP----GATGSPGEPGYMGLPGIQG---- 695

Query: 251 PLDRRGSVASPGEKGECGVRWREGR 275
              ++G   + GEKG  G +   GR
Sbjct: 696 ---KKGDKGNQGEKGIQGQKGENGR 717



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 59/206 (28%), Positives = 84/206 (40%), Gaps = 25/206 (12%)

Query: 85  GEAGHSEAAGEKGECGIPWTEGQVWRPLE--RRASVASPGEKGECG---VPWREGRVWRP 139
           G  G   A GEKG  G P   G    P    +   + SPG KGE G    P ++G    P
Sbjct: 545 GFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEP 604

Query: 140 -----------LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWR 188
                      + ++G +  PG++G+ G P   G +           +PG KG  G P  
Sbjct: 605 GIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPG-LMGSNGSPGQPGTPGSKGSKGEPGI 663

Query: 189 EG--GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLER--RASVASPGQKGECGVPWR 244
           +G  G        G+  SPGE G  G+P  +G+      +  +      G+ G  G+P +
Sbjct: 664 QGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQ 723

Query: 245 EGAVWRPLDRRGSVASPGEKGECGVR 270
           +G         G+    GEKGE GVR
Sbjct: 724 QGI----QGHHGAKGERGEKGEPGVR 745



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 53/187 (28%), Positives = 66/187 (35%), Gaps = 35/187 (18%)

Query: 85  GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
           G  GH  A GE+GE G P   G +             G KGE GV    G    P   +G
Sbjct: 725 GIQGHHGAKGERGEKGEPGVRGAI-------------GSKGESGVDGLMG----PAGPKG 767

Query: 145 SVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVW---RPLERRGS 201
               PG +G  G+  + G  +     R  V +   + +  V  + G +      L + GS
Sbjct: 768 QPGDPGPQGPPGLDGKPGREFSEQFIR-QVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGS 826

Query: 202 VASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASP 261
              PG  G  G     G              PG  G  GVP   G   RP   RG    P
Sbjct: 827 PGIPGPPGPIGPEGPRG-------------LPGLPGRDGVPGLVGVPGRP-GVRGLKGLP 872

Query: 262 GEKGECG 268
           G  GE G
Sbjct: 873 GRNGEKG 879


>gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo
            sapiens]
          Length = 2971

 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 58/202 (28%), Positives = 79/202 (39%), Gaps = 29/202 (14%)

Query: 85   GEAGHSEAAGEKGECGIPWTEGQVWRPLER--RASVASPGEKGECGVPWREGRVWRPLDR 142
            GE G     GE G+ G+P + G+   P  R  +      GE+G+ G+    G   +    
Sbjct: 1901 GEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE 1960

Query: 143  RGSVASPGEKGECGVPWREGGVWRPLE--------RRASVASPGQKGECGVPWREGGVWR 194
            RG     G+ G  GVP R+G    P E        RR    + G KG  G P  EG    
Sbjct: 1961 RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEG---- 2016

Query: 195  PLERRGSVASPGEKGECGVPWREGR--VWRPLERRASVASPGQKGECGVPWREGAVWRPL 252
                +G+  + G  G  G P   G   +  P     +  +PG++G  G          PL
Sbjct: 2017 ---EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTG----------PL 2063

Query: 253  DRRGSVASPGEKGECGVRWREG 274
             R+G    PG KG  G R   G
Sbjct: 2064 GRKGEPGEPGPKGGIGNRGPRG 2085



 Score = 65.9 bits (159), Expect = 4e-11
 Identities = 56/194 (28%), Positives = 78/194 (40%), Gaps = 26/194 (13%)

Query: 85   GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRP----- 139
            G+ G     GE+G+ GI    G   +  + R      G+ G  GVP R+G    P     
Sbjct: 1931 GDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGK 1990

Query: 140  ---LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPW--REGGVWR 194
                 RRG   + G KG  G P  EG        + +  + G  G  G P    E G+  
Sbjct: 1991 NGGFGRRGPPGAKGNKGGPGQPGFEG-------EQGTRGAQGPAGPAGPPGLIGEQGISG 2043

Query: 195  PLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDR 254
            P    G+  +PGE+G  G   R+G    P   +  + + G +GE G   R+G        
Sbjct: 2044 PRGSGGAAGAPGERGRTGPLGRKGEPGEP-GPKGGIGNRGPRGETGDDGRDGV------- 2095

Query: 255  RGSVASPGEKGECG 268
             GS    G+KGE G
Sbjct: 2096 -GSEGRRGKKGERG 2108



 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 57/193 (29%), Positives = 73/193 (37%), Gaps = 30/193 (15%)

Query: 85   GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDR-- 142
            G+ G     G  G  GIP  +G    P +       PGE+G  GV   +G    P  R  
Sbjct: 1832 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDE----GGPGERGPPGVNGTQGFQGCPGQRGV 1887

Query: 143  RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSV 202
            +GS   PGEKGE G    +G      ++      PG  GE G P R G        +G  
Sbjct: 1888 KGSRGFPGEKGEVGEIGLDGLDGEDGDK----GLPGSSGEKGNPGRRGD-------KGPR 1936

Query: 203  ASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPG 262
               GE+G+ G+    G   +  + R      G  G  GVP R+G              PG
Sbjct: 1937 GEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGV-------------PG 1983

Query: 263  EKGECGVRWREGR 275
              GE G     GR
Sbjct: 1984 GPGETGKNGGFGR 1996



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 52/167 (31%), Positives = 68/167 (40%), Gaps = 29/167 (17%)

Query: 123  EKGECGVPWR---EGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQ 179
            EK  CGVP +   +     P+   G    PGE G  G P  EGG             PG+
Sbjct: 1820 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGG-------------PGE 1866

Query: 180  KGECGVPWREGGVWRPLER--RGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKG 237
            +G  GV   +G    P +R  +GS   PGEKGE G    +G      ++      PG  G
Sbjct: 1867 RGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDK----GLPGSSG 1922

Query: 238  ECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREGRVWYSLDKRG 284
            E G P R G        +G     GE+G+ G+R   G       +RG
Sbjct: 1923 EKGNPGRRGD-------KGPRGEKGERGDVGIRGDPGNPGQDSQERG 1962



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 62/205 (30%), Positives = 81/205 (39%), Gaps = 30/205 (14%)

Query: 78   RPLR----SIDGE-AGHSEAAGEKGECGIPWT-EGQVWRPLERRASVASPGEKGECGVPW 131
            RPLR     +D E A   +   EK  CG+P    GQ       R      G  G  G+P 
Sbjct: 1798 RPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQ-------RGDRGPIGSIGPKGIPG 1850

Query: 132  REGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLER--RASVASPGQKGECGVPWRE 189
             +G    P D  G    PGE+G  GV   +G    P +R  + S   PG+KGE G    E
Sbjct: 1851 EDGYRGYPGDEGG----PGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVG----E 1902

Query: 190  GGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVW 249
             G+       G    PG  GE G P R G        +      G++G+ G+    G   
Sbjct: 1903 IGLDGLDGEDGDKGLPGSSGEKGNPGRRGD-------KGPRGEKGERGDVGIRGDPGNPG 1955

Query: 250  RPLDRRGSVASPGEKGECGVRWREG 274
            +    RG     G+ G  GV  R+G
Sbjct: 1956 QDSQERGPKGETGDLGPMGVPGRDG 1980


>gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
            sapiens]
          Length = 3177

 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 58/202 (28%), Positives = 79/202 (39%), Gaps = 29/202 (14%)

Query: 85   GEAGHSEAAGEKGECGIPWTEGQVWRPLER--RASVASPGEKGECGVPWREGRVWRPLDR 142
            GE G     GE G+ G+P + G+   P  R  +      GE+G+ G+    G   +    
Sbjct: 2107 GEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE 2166

Query: 143  RGSVASPGEKGECGVPWREGGVWRPLE--------RRASVASPGQKGECGVPWREGGVWR 194
            RG     G+ G  GVP R+G    P E        RR    + G KG  G P  EG    
Sbjct: 2167 RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEG---- 2222

Query: 195  PLERRGSVASPGEKGECGVPWREGR--VWRPLERRASVASPGQKGECGVPWREGAVWRPL 252
                +G+  + G  G  G P   G   +  P     +  +PG++G  G          PL
Sbjct: 2223 ---EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTG----------PL 2269

Query: 253  DRRGSVASPGEKGECGVRWREG 274
             R+G    PG KG  G R   G
Sbjct: 2270 GRKGEPGEPGPKGGIGNRGPRG 2291



 Score = 65.9 bits (159), Expect = 4e-11
 Identities = 56/194 (28%), Positives = 78/194 (40%), Gaps = 26/194 (13%)

Query: 85   GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRP----- 139
            G+ G     GE+G+ GI    G   +  + R      G+ G  GVP R+G    P     
Sbjct: 2137 GDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGK 2196

Query: 140  ---LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPW--REGGVWR 194
                 RRG   + G KG  G P  EG        + +  + G  G  G P    E G+  
Sbjct: 2197 NGGFGRRGPPGAKGNKGGPGQPGFEG-------EQGTRGAQGPAGPAGPPGLIGEQGISG 2249

Query: 195  PLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDR 254
            P    G+  +PGE+G  G   R+G    P   +  + + G +GE G   R+G        
Sbjct: 2250 PRGSGGAAGAPGERGRTGPLGRKGEPGEP-GPKGGIGNRGPRGETGDDGRDGV------- 2301

Query: 255  RGSVASPGEKGECG 268
             GS    G+KGE G
Sbjct: 2302 -GSEGRRGKKGERG 2314



 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 57/193 (29%), Positives = 73/193 (37%), Gaps = 30/193 (15%)

Query: 85   GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDR-- 142
            G+ G     G  G  GIP  +G    P +       PGE+G  GV   +G    P  R  
Sbjct: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDE----GGPGERGPPGVNGTQGFQGCPGQRGV 2093

Query: 143  RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSV 202
            +GS   PGEKGE G    +G      ++      PG  GE G P R G        +G  
Sbjct: 2094 KGSRGFPGEKGEVGEIGLDGLDGEDGDK----GLPGSSGEKGNPGRRGD-------KGPR 2142

Query: 203  ASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPG 262
               GE+G+ G+    G   +  + R      G  G  GVP R+G              PG
Sbjct: 2143 GEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGV-------------PG 2189

Query: 263  EKGECGVRWREGR 275
              GE G     GR
Sbjct: 2190 GPGETGKNGGFGR 2202



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 52/167 (31%), Positives = 68/167 (40%), Gaps = 29/167 (17%)

Query: 123  EKGECGVPWR---EGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQ 179
            EK  CGVP +   +     P+   G    PGE G  G P  EGG             PG+
Sbjct: 2026 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGG-------------PGE 2072

Query: 180  KGECGVPWREGGVWRPLER--RGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKG 237
            +G  GV   +G    P +R  +GS   PGEKGE G    +G      ++      PG  G
Sbjct: 2073 RGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDK----GLPGSSG 2128

Query: 238  ECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREGRVWYSLDKRG 284
            E G P R G        +G     GE+G+ G+R   G       +RG
Sbjct: 2129 EKGNPGRRGD-------KGPRGEKGERGDVGIRGDPGNPGQDSQERG 2168



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 62/205 (30%), Positives = 81/205 (39%), Gaps = 30/205 (14%)

Query: 78   RPLR----SIDGE-AGHSEAAGEKGECGIPWT-EGQVWRPLERRASVASPGEKGECGVPW 131
            RPLR     +D E A   +   EK  CG+P    GQ       R      G  G  G+P 
Sbjct: 2004 RPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQ-------RGDRGPIGSIGPKGIPG 2056

Query: 132  REGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLER--RASVASPGQKGECGVPWRE 189
             +G    P D  G    PGE+G  GV   +G    P +R  + S   PG+KGE G    E
Sbjct: 2057 EDGYRGYPGDEGG----PGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVG----E 2108

Query: 190  GGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVW 249
             G+       G    PG  GE G P R G        +      G++G+ G+    G   
Sbjct: 2109 IGLDGLDGEDGDKGLPGSSGEKGNPGRRGD-------KGPRGEKGERGDVGIRGDPGNPG 2161

Query: 250  RPLDRRGSVASPGEKGECGVRWREG 274
            +    RG     G+ G  GV  R+G
Sbjct: 2162 QDSQERGPKGETGDLGPMGVPGRDG 2186


>gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo
            sapiens]
          Length = 2570

 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 58/202 (28%), Positives = 79/202 (39%), Gaps = 29/202 (14%)

Query: 85   GEAGHSEAAGEKGECGIPWTEGQVWRPLER--RASVASPGEKGECGVPWREGRVWRPLDR 142
            GE G     GE G+ G+P + G+   P  R  +      GE+G+ G+    G   +    
Sbjct: 1500 GEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQE 1559

Query: 143  RGSVASPGEKGECGVPWREGGVWRPLE--------RRASVASPGQKGECGVPWREGGVWR 194
            RG     G+ G  GVP R+G    P E        RR    + G KG  G P  EG    
Sbjct: 1560 RGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEG---- 1615

Query: 195  PLERRGSVASPGEKGECGVPWREGR--VWRPLERRASVASPGQKGECGVPWREGAVWRPL 252
                +G+  + G  G  G P   G   +  P     +  +PG++G  G          PL
Sbjct: 1616 ---EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTG----------PL 1662

Query: 253  DRRGSVASPGEKGECGVRWREG 274
             R+G    PG KG  G R   G
Sbjct: 1663 GRKGEPGEPGPKGGIGNRGPRG 1684



 Score = 65.9 bits (159), Expect = 4e-11
 Identities = 56/194 (28%), Positives = 78/194 (40%), Gaps = 26/194 (13%)

Query: 85   GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRP----- 139
            G+ G     GE+G+ GI    G   +  + R      G+ G  GVP R+G    P     
Sbjct: 1530 GDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGK 1589

Query: 140  ---LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPW--REGGVWR 194
                 RRG   + G KG  G P  EG        + +  + G  G  G P    E G+  
Sbjct: 1590 NGGFGRRGPPGAKGNKGGPGQPGFEG-------EQGTRGAQGPAGPAGPPGLIGEQGISG 1642

Query: 195  PLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDR 254
            P    G+  +PGE+G  G   R+G    P   +  + + G +GE G   R+G        
Sbjct: 1643 PRGSGGAAGAPGERGRTGPLGRKGEPGEP-GPKGGIGNRGPRGETGDDGRDGV------- 1694

Query: 255  RGSVASPGEKGECG 268
             GS    G+KGE G
Sbjct: 1695 -GSEGRRGKKGERG 1707



 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 57/193 (29%), Positives = 73/193 (37%), Gaps = 30/193 (15%)

Query: 85   GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDR-- 142
            G+ G     G  G  GIP  +G    P +       PGE+G  GV   +G    P  R  
Sbjct: 1431 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDE----GGPGERGPPGVNGTQGFQGCPGQRGV 1486

Query: 143  RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSV 202
            +GS   PGEKGE G    +G      ++      PG  GE G P R G        +G  
Sbjct: 1487 KGSRGFPGEKGEVGEIGLDGLDGEDGDK----GLPGSSGEKGNPGRRGD-------KGPR 1535

Query: 203  ASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPG 262
               GE+G+ G+    G   +  + R      G  G  GVP R+G              PG
Sbjct: 1536 GEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGV-------------PG 1582

Query: 263  EKGECGVRWREGR 275
              GE G     GR
Sbjct: 1583 GPGETGKNGGFGR 1595



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 52/167 (31%), Positives = 68/167 (40%), Gaps = 29/167 (17%)

Query: 123  EKGECGVPWR---EGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQ 179
            EK  CGVP +   +     P+   G    PGE G  G P  EGG             PG+
Sbjct: 1419 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGG-------------PGE 1465

Query: 180  KGECGVPWREGGVWRPLER--RGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKG 237
            +G  GV   +G    P +R  +GS   PGEKGE G    +G      ++      PG  G
Sbjct: 1466 RGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDK----GLPGSSG 1521

Query: 238  ECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREGRVWYSLDKRG 284
            E G P R G        +G     GE+G+ G+R   G       +RG
Sbjct: 1522 EKGNPGRRGD-------KGPRGEKGERGDVGIRGDPGNPGQDSQERG 1561



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 62/205 (30%), Positives = 81/205 (39%), Gaps = 30/205 (14%)

Query: 78   RPLR----SIDGE-AGHSEAAGEKGECGIPWT-EGQVWRPLERRASVASPGEKGECGVPW 131
            RPLR     +D E A   +   EK  CG+P    GQ       R      G  G  G+P 
Sbjct: 1397 RPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQ-------RGDRGPIGSIGPKGIPG 1449

Query: 132  REGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLER--RASVASPGQKGECGVPWRE 189
             +G    P D  G    PGE+G  GV   +G    P +R  + S   PG+KGE G    E
Sbjct: 1450 EDGYRGYPGDEGG----PGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVG----E 1501

Query: 190  GGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVW 249
             G+       G    PG  GE G P R G        +      G++G+ G+    G   
Sbjct: 1502 IGLDGLDGEDGDKGLPGSSGEKGNPGRRGD-------KGPRGEKGERGDVGIRGDPGNPG 1554

Query: 250  RPLDRRGSVASPGEKGECGVRWREG 274
            +    RG     G+ G  GV  R+G
Sbjct: 1555 QDSQERGPKGETGDLGPMGVPGRDG 1579


>gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 64/214 (29%), Positives = 91/214 (42%), Gaps = 27/214 (12%)

Query: 71  PGSVPAPRPLRSIDGEAGHSE--AAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECG 128
           P  +P P+ LR   G+ G     A G KG  G+    G V  P          G+ G  G
Sbjct: 227 PKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLP--------GVGKPGVTG 278

Query: 129 VPWREGRVWRPLDRRGSVASPGEKGECGVPWREG-----GVWRPLER--RASVASPGQKG 181
            P  +G    PL + G+   PG +G  GVP  +G     G+ +P +         PG KG
Sbjct: 279 FPGPQG----PLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKG 334

Query: 182 ECGVPWREGGVWRP-LERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECG 240
           E G+P   G    P + + G     G++G  GVP   G    P   +  + +PG  G  G
Sbjct: 335 EQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALG----PRGEKGPIGAPGIGGPPG 390

Query: 241 VPWREGAVWRPLDRRGSVASPGEKGECGVRWREG 274
            P   G +  P+   G++  PG KGE G+   +G
Sbjct: 391 EPGLPG-IPGPMGPPGAIGFPGPKGEGGIVGPQG 423



 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 57/185 (30%), Positives = 76/185 (41%), Gaps = 16/185 (8%)

Query: 84  DGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASP-GEKGECGVPWREGRVWRPLDR 142
           DG  G     G KGE G+P   G    P   +     P G++G  GVP   G    P   
Sbjct: 321 DGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALG----PRGE 376

Query: 143 RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSV 202
           +G + +PG  G  G P   G +  P+    ++  PG KGE       GG+  P    G  
Sbjct: 377 KGPIGAPGIGGPPGEPGLPG-IPGPMGPPGAIGFPGPKGE-------GGIVGPQGPPGPK 428

Query: 203 ASPGEKGECGVPWREGRVWRPLER--RASVASPGQKGECGVPWREGAVWRPLDRRGSVAS 260
             PG +G  G P   G V  P  R     +   G+ G+ GVP   G V   L  +G    
Sbjct: 429 GEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPG-VPGLLGPKGEPGI 487

Query: 261 PGEKG 265
           PG++G
Sbjct: 488 PGDQG 492



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 65/228 (28%), Positives = 83/228 (36%), Gaps = 39/228 (17%)

Query: 70  KPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQ--------VWRPLERRASVASP 121
           KPG  P P+  R + G  G     GEKG  G P   G         +  P+    ++  P
Sbjct: 352 KPG-FPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFP 410

Query: 122 GEKGECGVPWREGRVWRPLDR--RGSVASPGEKGECGVPWREG--GVWRPLERRASVASP 177
           G KGE G+   +G      +   +G    PG  GE G P   G  G   P         P
Sbjct: 411 GPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVP 470

Query: 178 G---------QKGECGVPWREG--------GVWRPLERRGSVASPGEKGECGVPWREGRV 220
           G          KGE G+P  +G        G+  P    G    PG KGE G+P   G  
Sbjct: 471 GLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPG-- 528

Query: 221 WRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECG 268
                    +  PG  G  G P + GA+  P  + G    PG  G  G
Sbjct: 529 ------FPGIGKPGVAGLHGPPGKPGAL-GPQGQPGLPGPPGPPGPPG 569



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 44/147 (29%), Positives = 58/147 (39%), Gaps = 16/147 (10%)

Query: 70  KPGSVP--APRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGEC 127
           KPG +    P  +R + G  G    AG+KG  G+P   G     L  +     PG++G  
Sbjct: 439 KPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGL----LGPKGEPGIPGDQGLQ 494

Query: 128 GVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPW 187
           G P   G +  P    G    PG KGE G+P   G           +  PG  G  G P 
Sbjct: 495 GPPGIPG-IGGPSGPIGPPGIPGPKGEPGLPGPPG--------FPGIGKPGVAGLHGPPG 545

Query: 188 REGGVWRPLERRGSVASPGEKGECGVP 214
           + G +  P  + G    PG  G  G P
Sbjct: 546 KPGAL-GPQGQPGLPGPPGPPGPPGPP 571


>gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 64/214 (29%), Positives = 91/214 (42%), Gaps = 27/214 (12%)

Query: 71  PGSVPAPRPLRSIDGEAGHSE--AAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECG 128
           P  +P P+ LR   G+ G     A G KG  G+    G V  P          G+ G  G
Sbjct: 227 PKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLP--------GVGKPGVTG 278

Query: 129 VPWREGRVWRPLDRRGSVASPGEKGECGVPWREG-----GVWRPLER--RASVASPGQKG 181
            P  +G    PL + G+   PG +G  GVP  +G     G+ +P +         PG KG
Sbjct: 279 FPGPQG----PLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKG 334

Query: 182 ECGVPWREGGVWRP-LERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECG 240
           E G+P   G    P + + G     G++G  GVP   G    P   +  + +PG  G  G
Sbjct: 335 EQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALG----PRGEKGPIGAPGIGGPPG 390

Query: 241 VPWREGAVWRPLDRRGSVASPGEKGECGVRWREG 274
            P   G +  P+   G++  PG KGE G+   +G
Sbjct: 391 EPGLPG-IPGPMGPPGAIGFPGPKGEGGIVGPQG 423



 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 57/185 (30%), Positives = 76/185 (41%), Gaps = 16/185 (8%)

Query: 84  DGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASP-GEKGECGVPWREGRVWRPLDR 142
           DG  G     G KGE G+P   G    P   +     P G++G  GVP   G    P   
Sbjct: 321 DGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALG----PRGE 376

Query: 143 RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSV 202
           +G + +PG  G  G P   G +  P+    ++  PG KGE       GG+  P    G  
Sbjct: 377 KGPIGAPGIGGPPGEPGLPG-IPGPMGPPGAIGFPGPKGE-------GGIVGPQGPPGPK 428

Query: 203 ASPGEKGECGVPWREGRVWRPLER--RASVASPGQKGECGVPWREGAVWRPLDRRGSVAS 260
             PG +G  G P   G V  P  R     +   G+ G+ GVP   G V   L  +G    
Sbjct: 429 GEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPG-VPGLLGPKGEPGI 487

Query: 261 PGEKG 265
           PG++G
Sbjct: 488 PGDQG 492



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 65/228 (28%), Positives = 83/228 (36%), Gaps = 39/228 (17%)

Query: 70  KPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQ--------VWRPLERRASVASP 121
           KPG  P P+  R + G  G     GEKG  G P   G         +  P+    ++  P
Sbjct: 352 KPG-FPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFP 410

Query: 122 GEKGECGVPWREGRVWRPLDR--RGSVASPGEKGECGVPWREG--GVWRPLERRASVASP 177
           G KGE G+   +G      +   +G    PG  GE G P   G  G   P         P
Sbjct: 411 GPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVP 470

Query: 178 G---------QKGECGVPWREG--------GVWRPLERRGSVASPGEKGECGVPWREGRV 220
           G          KGE G+P  +G        G+  P    G    PG KGE G+P   G  
Sbjct: 471 GLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPG-- 528

Query: 221 WRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECG 268
                    +  PG  G  G P + GA+  P  + G    PG  G  G
Sbjct: 529 ------FPGIGKPGVAGLHGPPGKPGAL-GPQGQPGLPGPPGPPGPPG 569



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 44/147 (29%), Positives = 58/147 (39%), Gaps = 16/147 (10%)

Query: 70  KPGSVP--APRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGEC 127
           KPG +    P  +R + G  G    AG+KG  G+P   G     L  +     PG++G  
Sbjct: 439 KPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGL----LGPKGEPGIPGDQGLQ 494

Query: 128 GVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPW 187
           G P   G +  P    G    PG KGE G+P   G           +  PG  G  G P 
Sbjct: 495 GPPGIPG-IGGPSGPIGPPGIPGPKGEPGLPGPPG--------FPGIGKPGVAGLHGPPG 545

Query: 188 REGGVWRPLERRGSVASPGEKGECGVP 214
           + G +  P  + G    PG  G  G P
Sbjct: 546 KPGAL-GPQGQPGLPGPPGPPGPPGPP 571


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 68.6 bits (166), Expect = 7e-12
 Identities = 68/218 (31%), Positives = 87/218 (39%), Gaps = 32/218 (14%)

Query: 70   KPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASP-GEKGECG 128
            +PG  P P   R  DGE G     G  G+ G+P   G+  R L     V  P GEKG+ G
Sbjct: 1620 RPGP-PGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGE--RGLRGAPGVRGPVGEKGDQG 1676

Query: 129  VPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPG--QKGECGVP 186
             P  +G       R GS  S G KG+ G P   G   R ++       PG  +KGE G  
Sbjct: 1677 DPGEDG-------RNGSPGSSGPKGDRGEPGPPGPPGRLVD-----TGPGAREKGEPGDR 1724

Query: 187  WREGGVWRPLERRGSVASPGEKGECGV--------PWREGRVWRPLERRASVASPGQKGE 238
             +EG    P   +G    PG  GE G+        P  +  V  P   +     PG  G 
Sbjct: 1725 GQEG----PRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGR 1780

Query: 239  CGVPWREGAVW--RPLDRRGSVASPGEKGECGVRWREG 274
             G+  + GA     P    G    PG  G  G+R  +G
Sbjct: 1781 SGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQG 1818



 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 68/214 (31%), Positives = 83/214 (38%), Gaps = 26/214 (12%)

Query: 75   PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
            P P  L    G  G     GE G+ G P  +G   +  +R     SPG  G  G+P   G
Sbjct: 2232 PGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDR----GSPGVPGSPGLPGPVG 2287

Query: 135  RVWRP----LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
                P       +  V  PG KGE G P   GG+   L     V  PG KG+ G+P   G
Sbjct: 2288 PKGEPGPTGAPGQAVVGLPGAKGEKGAP---GGLAGDL-----VGEPGAKGDRGLPGPRG 2339

Query: 191  GVWRPLERRGSVASPGEKGECGVPWREGRVWRP----LERRASVASPGQKGECGVPWREG 246
                   R G    PGE G+ G P  +G    P             PG KG+ G+P   G
Sbjct: 2340 EKGE-AGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPG 2398

Query: 247  A---VWRP--LDRRGSVASPGEKGECGVRWREGR 275
            A   V  P     RG +  PG  GE G+    GR
Sbjct: 2399 APGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGR 2432



 Score = 65.9 bits (159), Expect = 4e-11
 Identities = 62/202 (30%), Positives = 79/202 (39%), Gaps = 22/202 (10%)

Query: 84   DGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPG--EKGECGVPWREGRVWRPLD 141
            DG  G   ++G KG+ G P   G   R ++       PG  EKGE G   +EG    P  
Sbjct: 1681 DGRNGSPGSSGPKGDRGEPGPPGPPGRLVD-----TGPGAREKGEPGDRGQEG----PRG 1731

Query: 142  RRGSVASPGEKGECGV--------PWREGGVWRPLERRASVASPGQKGECGVPWREGGVW 193
             +G    PG  GE G+        P  + GV  P   +     PG  G  G+  + G   
Sbjct: 1732 PKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAA- 1790

Query: 194  RPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLD 253
             P    G+    G+ G  G+P   G    P         PG+ GE G P   G    P D
Sbjct: 1791 GPSGPNGAAGKAGDPGRDGLPGLRGEQGLP-GPSGPPGLPGKPGEDGKPGLNGKNGEPGD 1849

Query: 254  RRGSVASPGEKGECGVRWREGR 275
              G     GEKG+ G   REGR
Sbjct: 1850 -PGEDGRKGEKGDSGASGREGR 1870



 Score = 65.1 bits (157), Expect = 7e-11
 Identities = 74/251 (29%), Positives = 91/251 (36%), Gaps = 51/251 (20%)

Query: 67   LSAKPGS-----VPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASP 121
            L  +PG+     +P PR  +   G AG     GE G+ G P  +G    P      V  P
Sbjct: 2322 LVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDP-----GVGVP 2376

Query: 122  GEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKG 181
            G  G  G P  +G +  P         PG  G  G P + G    P          G++G
Sbjct: 2377 GSPGPPGPPGVKGDLGLP-------GLPGAPGVVGFPGQTG----PRGEMGQPGPSGERG 2425

Query: 182  ECGVPWREG--GVWRPLERRGSVASPGE---KGECGVPWREGRVWRPLERRASVASPGQK 236
              G P REG  G   P    GSV  PG    KG+ G P               V  PG +
Sbjct: 2426 LAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDP--------------GVGLPGPR 2471

Query: 237  GECGVPWREGAVWRPLDR--RGSVASPGEKGECGVRWREGRVWYSLDKRGSVPAALASQR 294
            GE G P   G   RP     RG    PG +GE G +   G      DK  S         
Sbjct: 2472 GERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSA-------- 2523

Query: 295  HALLALPQPQG 305
              +L  P P+G
Sbjct: 2524 -VILGPPGPRG 2533



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 63/226 (27%), Positives = 88/226 (38%), Gaps = 27/226 (11%)

Query: 70   KPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQ---VWRPLERRASVASPGEKGE 126
            +PG    PR L    G  G     G+ G  G+   +G    +  P   R +    GE+G 
Sbjct: 2485 RPGQ-EGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGP 2543

Query: 127  CGVPWREGRVWRPLDR--RGSVASPGEKGECGVPWREGGVWRPLERRAS--VASPGQKGE 182
             G+   +G      D   +GS   PG+KG  G+P   G +    +  A+     PG  G+
Sbjct: 2544 RGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGK 2603

Query: 183  CGVPWREG-----GVWRPLERRGS---------VASPGEKGECGVPWREGRVWRPLERRA 228
             GVP   G     G   P   +G              G+KGE G P R G        + 
Sbjct: 2604 DGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLA----GHKG 2659

Query: 229  SVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREG 274
             +  PG  G+ G P +EG +  P   RG    PG KG+ G +   G
Sbjct: 2660 EMGEPGVPGQSGAPGKEGLI-GPKGDRGFDGQPGPKGDQGEKGERG 2704



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 73/236 (30%), Positives = 89/236 (37%), Gaps = 45/236 (19%)

Query: 71   PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASP--------- 121
            PG    P+  R   G  G     GE+G  G P +   V R LE     AS          
Sbjct: 1906 PGGT-GPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWD 1964

Query: 122  -----------------GEKGECGVPWREGRVWRPLDR--RGSVASPGEKGECGVPWREG 162
                             G+ GE G P +EG +  P +R  +G    PG +G  G+   E 
Sbjct: 1965 ESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGER 2024

Query: 163  GVWRPLERRASVASPGQKGECGVPWREGGV---WRPLER--RGSVASPGEKGECGVPWRE 217
            G   P         PG+ G  G+P R GGV    RP ER  RG     GE+G  G P   
Sbjct: 2025 G---PPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLP 2081

Query: 218  GRVWRPLERRASVA----SPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECGV 269
            G    P      V+     PG  GE G P  +GA   P    GS    G KG+ GV
Sbjct: 2082 GTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEP----GSNGDQGPKGDRGV 2133



 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 61/202 (30%), Positives = 83/202 (41%), Gaps = 21/202 (10%)

Query: 77   PRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGR- 135
            P  L+   GE G +   G KG+ G+P  +G    P   R    +PG  GE G+   EG+ 
Sbjct: 2109 PPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEP-GPRGQDGNPGLPGERGMAGPEGKP 2167

Query: 136  -VWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWR 194
             +  P    G V   G+ G  G P    G+  P   +      G+ GE G P R  G+  
Sbjct: 2168 GLQGPRGPPGPVGGHGDPGPPGAP----GLAGPAGPQGPSGLKGEPGETGPPGR--GLTG 2221

Query: 195  PLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDR 254
            P    G+V  PG  G  G+   +G    P          G+ G+ G P R+GA  +  DR
Sbjct: 2222 P---TGAVGLPGPPGPSGLVGPQGSPGLP-------GQVGETGKPGAPGRDGASGKDGDR 2271

Query: 255  --RGSVASPGEKGECGVRWREG 274
               G   SPG  G  G +   G
Sbjct: 2272 GSPGVPGSPGLPGPVGPKGEPG 2293



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 62/212 (29%), Positives = 83/212 (39%), Gaps = 33/212 (15%)

Query: 71   PGSVPAPRPLRSIDGEAGHSEAAGEKGE--CGIPWTEGQVWRPLERRASVASPGEKGECG 128
            PG +  P P  S+ G  G S   G+KG+   G+P   G+             PG +GE G
Sbjct: 2436 PGPLGPPGPPGSV-GPPGASGLKGDKGDPGVGLPGPRGER----------GEPGIRGEDG 2484

Query: 129  VPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWR 188
             P +EG    P    G   S GE+GE G     G      +    +  PG +G  G    
Sbjct: 2485 RPGQEG----PRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGE 2540

Query: 189  EG--GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREG 246
             G  G+      RG    PG+KG  G P  +G    P   R  +   GQ G  G+P    
Sbjct: 2541 RGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLP-GLRGLLGPQGQPGAAGIP---- 2595

Query: 247  AVWRPLDRRGSVASPGEKGECGVRWREGRVWY 278
                     G   SPG+ G  G+R  +G V +
Sbjct: 2596 ---------GDPGSPGKDGVPGIRGEKGDVGF 2618



 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 70/234 (29%), Positives = 92/234 (39%), Gaps = 26/234 (11%)

Query: 47   GAQPREDQMGSVEKLTTSAFLSAK-PGSVPAP--RPLRSIDGEAGHSEAAGEKGECGIPW 103
            GA  RE + G   +      L  + P  +P P   P +   G  G +   G++GE G   
Sbjct: 1863 GASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKG 1922

Query: 104  TEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREG- 162
             +G              PGE+G  G P     V R L+  G  AS     E    W E  
Sbjct: 1923 EQGL-------------PGERGLRGEPGSVPNVDRLLETAGIKASALR--EIVETWDESS 1967

Query: 163  GVWRPLERRASVASPGQKGECGVPWREGGVWRPLER--RGSVASPGEKGECGVPWREGRV 220
            G + P+  R      G  GE G P +EG +  P ER  +G    PG +G  G+   E   
Sbjct: 1968 GSFLPVPERRR-GPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERG- 2025

Query: 221  WRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWREG 274
              P         PG+ G  G+P R G V     R G     GEKGE G + R+G
Sbjct: 2026 --PPGPSGLAGEPGKPGIPGLPGRAGGVGEA-GRPGERGERGEKGERGEQGRDG 2076



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 68/216 (31%), Positives = 86/216 (39%), Gaps = 39/216 (18%)

Query: 71   PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
            PG   AP P        G   +A  KGE G P  +G+   P  R  +  +PG  G  G P
Sbjct: 1277 PGRTGAPGP-------QGPPGSATAKGERGFPGADGRPGSP-GRAGNPGTPGAPGLKGSP 1328

Query: 131  WREGRVWRPLDR--RGSVASPGEKGEC------GVPWREG--GVWRPLERRASVASPGQK 180
               G    P +R  RG    PG  G+       G+P R+G  G   P   R  +  PG +
Sbjct: 1329 GLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPR 1388

Query: 181  GECGVPWR--------EGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVAS 232
            G  G+P           G    P    G +A PGE G  G+P   G        +  V  
Sbjct: 1389 GPPGLPGTAMKGDKGDRGERGPPGPGEGGIA-PGEPGLPGLPGSPG-------PQGPVGP 1440

Query: 233  PGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECG 268
            PG+KGE G    +GA   P    G   SPGE+G  G
Sbjct: 1441 PGKKGEKG-DSEDGAPGLP----GQPGSPGEQGPRG 1471



 Score = 58.2 bits (139), Expect = 9e-09
 Identities = 68/228 (29%), Positives = 82/228 (35%), Gaps = 39/228 (17%)

Query: 71   PGSVPAPRPLRSIDGEAGHSEAAGEKG--ECGIPWTEGQVWRPLER--RASVASPGEKGE 126
            PG   +P P     G  G     GEKG  E G P   GQ   P E+  R    + G KG+
Sbjct: 1426 PGLPGSPGP----QGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGD 1481

Query: 127  CGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRP-LERRASVASP-------G 178
             G P             G +   GEKGE G P   G    P +  R     P       G
Sbjct: 1482 RGFP-------------GPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTG 1528

Query: 179  QKGECGVPWREG-------GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASV- 230
            ++GE G P R G        V  P   +G V   G +G  GV    G     L       
Sbjct: 1529 RQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPK 1588

Query: 231  ASPGQKGECGVPWREGAVWR--PLDRRGSVASPGEKGECGVRWREGRV 276
              PG +G  G+  R G      P   +G    PG  G  G R R+G V
Sbjct: 1589 GDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEV 1636



 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 48/170 (28%), Positives = 59/170 (34%), Gaps = 34/170 (20%)

Query: 68   SAKPGS--VPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKG 125
            S  PG   +  P+  R  DG+ G     GEKGE G P   G               G  G
Sbjct: 2670 SGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGG----------FPGPSGNDG 2719

Query: 126  ECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGV 185
              G P   G V      RG     G+KGE G P       R +       +PG++GE G 
Sbjct: 2720 SAGPPGPPGSV----GPRGPEGLQGQKGERGPPGE-----RVVGAPGVPGAPGERGEQGR 2770

Query: 186  PWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQ 235
            P             G     GEKGE  +   + R +   E     A  GQ
Sbjct: 2771 P-------------GPAGPRGEKGEAALTEDDIRGFVRQEMSQHCACQGQ 2807


>gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]
          Length = 1028

 Score = 68.6 bits (166), Expect = 7e-12
 Identities = 66/218 (30%), Positives = 82/218 (37%), Gaps = 30/218 (13%)

Query: 75  PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
           P  R     +GE G     GEKGE G P   G +  P+  +      G +GE G    +G
Sbjct: 259 PGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDL-GPVGYQGMKGEKGSRGEKGSRGPKG 317

Query: 135 RVWRPLDRRGSVASPGEKGECGVPWREG--------GVWRPLERRASVASPGQKGECGVP 186
                  +RG     G KGE G P   G        G+  P   +    + G KGE G P
Sbjct: 318 YKGEK-GKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376

Query: 187 WREGGVWRPLE--------RRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGE 238
             +G   RP          + G    PGEKGE G     G    P ER      PG++G 
Sbjct: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGER----GGPGERGP 432

Query: 239 CGVPWREGAVWRPLD--------RRGSVASPGEKGECG 268
            G P   G    P +        R G V  PG+ GE G
Sbjct: 433 RGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAG 470



 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 56/183 (30%), Positives = 68/183 (37%), Gaps = 38/183 (20%)

Query: 107 QVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWR 166
           QV    E + +   PG +G+ G    EG        RG    PGEKGE G P R G +  
Sbjct: 245 QVCCSFECQPARGPPGLRGDPGF---EGE-------RGKPGLPGEKGEAGDPGRPGDL-- 292

Query: 167 PLERRASVASPGQKGECGVPWREG-----GVWRPLERRGSVASPGEKGECGVPWREG--- 218
                  V   G KGE G    +G     G      +RG     G KGE G P   G   
Sbjct: 293 -----GPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKG 347

Query: 219 -----RVWRPLERRASVASPGQKGECGVPWREGAVWRP--------LDRRGSVASPGEKG 265
                 +  P   +    + G KGE G P  +G   RP          + G    PGEKG
Sbjct: 348 SPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKG 407

Query: 266 ECG 268
           E G
Sbjct: 408 EAG 410



 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 45/176 (25%), Positives = 61/176 (34%), Gaps = 20/176 (11%)

Query: 71  PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
           P   P  R  R   GEAG     G +G  G+P   G+          +   G +G+ G P
Sbjct: 432 PRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEA-------GPIGPKGYRGDEGPP 484

Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
             EG    P    G    PG+ G  G    +G      E       PG  G  G P   G
Sbjct: 485 GSEGARGAP----GPAGPPGDPGLMGERGEDGPAGNGTE--GFPGFPGYPGNRGAPGING 538

Query: 191 GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREG 246
                   +G     G++GE G P  +     P   + +    G +G  G P  +G
Sbjct: 539 -------TKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQG 587


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.135    0.445 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,600,329
Number of Sequences: 37866
Number of extensions: 919071
Number of successful extensions: 7808
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 100
Number of HSP's successfully gapped in prelim test: 195
Number of HSP's that attempted gapping in prelim test: 2156
Number of HSP's gapped (non-prelim): 1574
length of query: 305
length of database: 18,247,518
effective HSP length: 102
effective length of query: 203
effective length of database: 14,385,186
effective search space: 2920192758
effective search space used: 2920192758
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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