Guide to the Human Genome
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Search of human proteins with 239751471

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239751471 PREDICTED: hypothetical protein XP_002347846 [Homo
sapiens]
         (870 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239751471 PREDICTED: hypothetical protein XP_002347846 [Homo ...  1768   0.0  
gi|239745974 PREDICTED: hypothetical protein XP_002343630 [Homo ...   571   e-163
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     67   9e-11
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    64   6e-10
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    64   6e-10
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    60   9e-09
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    60   9e-09
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    60   9e-09
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       60   9e-09
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      58   3e-08
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]                58   4e-08
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]    57   6e-08
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      57   1e-07
gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ...    56   1e-07
gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo s...    56   1e-07
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    56   2e-07
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       54   5e-07
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]        54   5e-07
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     53   1e-06
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]         52   2e-06
gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [H...    51   5e-06
gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Ho...    51   5e-06
gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Hom...    51   5e-06
gi|22027607 alpha 1 type XIII collagen isoform 18 [Homo sapiens]       50   7e-06
gi|22027603 alpha 1 type XIII collagen isoform 16 [Homo sapiens]       50   7e-06
gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens]     50   9e-06
gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens]         50   1e-05
gi|239748777 PREDICTED: hypothetical protein [Homo sapiens]            49   2e-05
gi|239756550 PREDICTED: hypothetical protein XP_002344932 [Homo ...    49   3e-05
gi|239745514 PREDICTED: hypothetical protein XP_002343509 [Homo ...    49   3e-05

>gi|239751471 PREDICTED: hypothetical protein XP_002347846 [Homo
           sapiens]
          Length = 870

 Score = 1768 bits (4580), Expect = 0.0
 Identities = 870/870 (100%), Positives = 870/870 (100%)

Query: 1   MRTKPGCVRVRVQGRRPRFIPGEKGEKRRTKQIIAAQAGGEGGRAQPGLPCSVDLATGLE 60
           MRTKPGCVRVRVQGRRPRFIPGEKGEKRRTKQIIAAQAGGEGGRAQPGLPCSVDLATGLE
Sbjct: 1   MRTKPGCVRVRVQGRRPRFIPGEKGEKRRTKQIIAAQAGGEGGRAQPGLPCSVDLATGLE 60

Query: 61  GPLGGPAVDLDVGFSPGDDIAGQSLGAAGGQVVHLPGGQLAVPDVEVGQLTHKCLGGIKP 120
           GPLGGPAVDLDVGFSPGDDIAGQSLGAAGGQVVHLPGGQLAVPDVEVGQLTHKCLGGIKP
Sbjct: 61  GPLGGPAVDLDVGFSPGDDIAGQSLGAAGGQVVHLPGGQLAVPDVEVGQLTHKCLGGIKP 120

Query: 121 TTQSYLLLAQHQHALGLDGVIGRQVLATATLRAILVGLPDPVPGGPVYTTSPSLHQGEPS 180
           TTQSYLLLAQHQHALGLDGVIGRQVLATATLRAILVGLPDPVPGGPVYTTSPSLHQGEPS
Sbjct: 121 TTQSYLLLAQHQHALGLDGVIGRQVLATATLRAILVGLPDPVPGGPVYTTSPSLHQGEPS 180

Query: 181 LVSEFTAASQGSVRHLCSLLAGLSSLFRCPISSCYTLSLYNTSISGSLLWRGKASSKASW 240
           LVSEFTAASQGSVRHLCSLLAGLSSLFRCPISSCYTLSLYNTSISGSLLWRGKASSKASW
Sbjct: 181 LVSEFTAASQGSVRHLCSLLAGLSSLFRCPISSCYTLSLYNTSISGSLLWRGKASSKASW 240

Query: 241 WRSPDHIIGQGQAPWLVLRHLPYPPQEASGKVQLSLLSQYRPDVPLTHQCLLGVRLGSSP 300
           WRSPDHIIGQGQAPWLVLRHLPYPPQEASGKVQLSLLSQYRPDVPLTHQCLLGVRLGSSP
Sbjct: 241 WRSPDHIIGQGQAPWLVLRHLPYPPQEASGKVQLSLLSQYRPDVPLTHQCLLGVRLGSSP 300

Query: 301 PPRPFLGAGTLPGALLRGQGSKELGVLWAPGLPKVTALGCRHTLSYITSLKMALFKSVRH 360
           PPRPFLGAGTLPGALLRGQGSKELGVLWAPGLPKVTALGCRHTLSYITSLKMALFKSVRH
Sbjct: 301 PPRPFLGAGTLPGALLRGQGSKELGVLWAPGLPKVTALGCRHTLSYITSLKMALFKSVRH 360

Query: 361 ILRSEQGHVALLRTGHPPPSPFTTLFDFCDFKTEPPALIQAPWGVHPGQHLPLQLIDLAL 420
           ILRSEQGHVALLRTGHPPPSPFTTLFDFCDFKTEPPALIQAPWGVHPGQHLPLQLIDLAL
Sbjct: 361 ILRSEQGHVALLRTGHPPPSPFTTLFDFCDFKTEPPALIQAPWGVHPGQHLPLQLIDLAL 420

Query: 421 QQILEAVGLAGGIEAAVLLRGARAGETTPLGEARGPCWKARGAVPSGRLRGRPGRVAGAS 480
           QQILEAVGLAGGIEAAVLLRGARAGETTPLGEARGPCWKARGAVPSGRLRGRPGRVAGAS
Sbjct: 421 QQILEAVGLAGGIEAAVLLRGARAGETTPLGEARGPCWKARGAVPSGRLRGRPGRVAGAS 480

Query: 481 GRRGASQARGGTGRAPARLRRGRGMPGRVGNGVGEGRGASEPEGEPEPRARADLEVLQAG 540
           GRRGASQARGGTGRAPARLRRGRGMPGRVGNGVGEGRGASEPEGEPEPRARADLEVLQAG
Sbjct: 481 GRRGASQARGGTGRAPARLRRGRGMPGRVGNGVGEGRGASEPEGEPEPRARADLEVLQAG 540

Query: 541 FERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGW 600
           FERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGW
Sbjct: 541 FERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGW 600

Query: 601 TTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPV 660
           TTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPV
Sbjct: 601 TTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPV 660

Query: 661 VNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLAD 720
           VNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLAD
Sbjct: 661 VNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLAD 720

Query: 721 RAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLR 780
           RAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLR
Sbjct: 721 RAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLR 780

Query: 781 GRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEA 840
           GRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEA
Sbjct: 781 GRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEA 840

Query: 841 GSMETFLRNGGLYPPPSPRAPAVCVQHLSF 870
           GSMETFLRNGGLYPPPSPRAPAVCVQHLSF
Sbjct: 841 GSMETFLRNGGLYPPPSPRAPAVCVQHLSF 870


>gi|239745974 PREDICTED: hypothetical protein XP_002343630 [Homo
           sapiens]
          Length = 538

 Score =  571 bits (1472), Expect = e-163
 Identities = 308/430 (71%), Positives = 317/430 (73%), Gaps = 36/430 (8%)

Query: 472 RPGRVAGASGRRGASQARGGTGRA--PARLRRGRGMPGRVGNGVGEGRGASEPEGEPEPR 529
           RP  +A  +GR G   AR G G    PAR    R          G     +   G P  R
Sbjct: 114 RPAGMAAGTGRSGPGSARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSG-PHCR 172

Query: 530 ARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLA------- 582
            R       A      S      R  GR P  +  G   R G    +A PGL        
Sbjct: 173 LRCGARAFYAAAGGASS----RRRQRGRNPALIVRGPGPRRGGGLTSAPPGLPPLASPPP 228

Query: 583 --------------GSGV--QRALALAAAQLG------GWTTCVVSPNLRRGSRRAGNHR 620
                         G  +  +R   L   ++G      GWTTCVVSPNLRRGSRRAGNHR
Sbjct: 229 FWELPRPPPPPPPPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHR 288

Query: 621 VREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPG 680
           VREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPG
Sbjct: 289 VREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPG 348

Query: 681 RPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGW 740
           RPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGW
Sbjct: 349 RPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGW 408

Query: 741 TFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGL 800
           TFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGL
Sbjct: 409 TFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGL 468

Query: 801 CVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRA 860
           CVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRA
Sbjct: 469 CVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRA 528

Query: 861 PAVCVQHLSF 870
           PAVCVQHLSF
Sbjct: 529 PAVCVQHLSF 538



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 50/177 (28%), Positives = 59/177 (33%), Gaps = 39/177 (22%)

Query: 632 AALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLC 691
           A +    P    AG G  GP S+            GL +   P R    R A      L 
Sbjct: 108 AQVRAARPAGMAAGTGRSGPGSA----------RLGLGSGWDPARAVAPRAARALGAALF 157

Query: 692 GPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAP 751
           G       LS P  C    G         RAF    AG  + RRR+RG   A  +R   P
Sbjct: 158 GRAVHTAALSGPH-CRLRCGA--------RAF-YAAAGGASSRRRQRGRNPALIVRGPGP 207

Query: 752 RE-------QPPASPAASP---CQAPRAPEKETE-----APR----LRGRATAVAPR 789
           R         P   P ASP    + PR P           PR    LRG+   + PR
Sbjct: 208 RRGGGLTSAPPGLPPLASPPPFWELPRPPPPPPPPGPALLPRRLRELRGKEVGLRPR 264


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 66.6 bits (161), Expect = 9e-11
 Identities = 135/487 (27%), Positives = 163/487 (33%), Gaps = 112/487 (22%)

Query: 445 GETTPLGEA--RGPCWKARGAVPSGR--LRGRPGR--VAGASGRRGASQARGGTGRA-PA 497
           G   P GE   RGP  +A  A P G   LRG PG   + GA GR G     G  G + PA
Sbjct: 370 GPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPA 429

Query: 498 RLRRGRGMPGRVGN-GVGEGRGASEPEGEPEPRARADLEVLQAGFERLQSLPELAERLGG 556
            +R   G  GR G  G+   RG     G   P  +        G   +   P      G 
Sbjct: 430 GVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEG----PVGLPGIDGRPGPIGPAGA 485

Query: 557 RC-PGQVA-------------HGVLARAGLLAAAARPGLAGS-GVQRALALAAAQLGGWT 601
           R  PG +              +G    AGL  A   PG  G+ G Q        Q G   
Sbjct: 486 RGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGE 545

Query: 602 TCVVSPNLRRG-------SRRAGNHRVREIEFGSALLAALNTLG----PGSFGAG----- 645
                P   +G       +   G    R +     L       G    PG  GA      
Sbjct: 546 QGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGP 605

Query: 646 LGAQGPRSSTPECPVVNGSEWGL------AAPLSP-----------------ERGSPGRP 682
           +G++GP  S P  P  N  E G+      A P  P                 E+G PG  
Sbjct: 606 IGSRGP--SGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLR 663

Query: 683 AFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTF 742
             + +PG  G    PG +  P P G   GD  EA  A  A P   AGP            
Sbjct: 664 GEIGNPGRDGARGAPGAVGAPGPAG-ATGDRGEAGAAGPAGP---AGP------------ 707

Query: 743 AAALRKGAPREQPPASPA-----ASPCQAPRAP--EKETEAPRLRGRATAVAPRPLPAAP 795
                +G+P E+    PA     A P  A   P  + E  A   +G    V P     A 
Sbjct: 708 -----RGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAA 762

Query: 796 GFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPP 855
           G +G     P PA SRG G P   G TG PG   R   P                G+  P
Sbjct: 763 GPAGPNG-PPGPAGSRGDGGP--PGMTGFPGAAGRTGPPGP-------------SGISGP 806

Query: 856 PSPRAPA 862
           P P  PA
Sbjct: 807 PGPPGPA 813



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 121/429 (28%), Positives = 141/429 (32%), Gaps = 67/429 (15%)

Query: 445 GETTPLGEARGPCWKA--RGAVPSGRLRGRPGRVA--GASGRRGASQARGGTGRAPARLR 500
           GE   +G A GP   A  RG V    L G  G     GA+G  GA  A G  G A A   
Sbjct: 265 GEIGAVGNA-GPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGL 323

Query: 501 RG-RGMPGRVGNGVGEGRGASEPEGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCP 559
            G RG+PG VG       GA    GEP P           G    +  P  A   G   P
Sbjct: 324 PGPRGIPGPVG--AAGATGARGLVGEPGPAG-------SKGESGNKGEPGSAGPQGPPGP 374

Query: 560 G--QVAHGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAG 617
              +   G    AG       PGL GS   R L  A  + G     V+ P   RG+  +G
Sbjct: 375 SGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAG-----VMGPPGSRGA--SG 427

Query: 618 NHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERG 677
              VR     +        +GP       G  GP     E PV      G   P+ P  G
Sbjct: 428 PAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGK--EGPVGLPGIDGRPGPIGPA-G 484

Query: 678 SPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRR 737
           + G P  +  PG  GP   PG            GD   A LA      RGA    G    
Sbjct: 485 ARGEPGNIGFPGPKGPTGDPGK----------NGDKGHAGLAG----ARGAPGPDGNNGA 530

Query: 738 RGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLR------GRATAVAPRPL 791
           +G      ++ G   + PP  P       P  P  E   P  R      G      PR  
Sbjct: 531 QGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGE 590

Query: 792 PAAPGFSGLCVLQPFPARSRG-------------------LGVPSQQGPTGSPGCRDRAS 832
              PG SG       P  SRG                   +G     GP+G PG R  A 
Sbjct: 591 RGPPGESG-AAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAG 649

Query: 833 APRAGAEAG 841
            P    E G
Sbjct: 650 IPGGKGEKG 658



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 126/471 (26%), Positives = 160/471 (33%), Gaps = 95/471 (20%)

Query: 462 GAVPSGRL--RGRPGRVAGASGRRGASQARGGTGR----APARLRRGRGMPGRVGNGVGE 515
           G  P G +  RG PG  AGA G +G     G  G      PA  R   G PG+ G     
Sbjct: 89  GPGPMGLMGPRGPPG-AAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHP 147

Query: 516 G-------RGASEPEGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLA 568
           G       RG   P+G         L     GF+ ++    L + L G+ PG  A GV  
Sbjct: 148 GKPGRPGERGVVGPQGARGFPGTPGLP----GFKGIRGHNGL-DGLKGQ-PG--APGVKG 199

Query: 569 RAGLLAAAARPGLAGS-------GVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRV 621
             G       PG  G+       G   A   A A+    +   V P    GS  AG    
Sbjct: 200 EPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGS--AGPPGF 257

Query: 622 REIEFGSALLAALNTLGPGSFGAGLGAQG-PRSSTPECPVVNGSEWGLAAPLSPERGSPG 680
                    + A+   GP       G  G P  S P  P  N    GL       +G+ G
Sbjct: 258 PGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGA----KGAAG 313

Query: 681 RPAFLRSPGLCGPGPVPGGLSV------------PTPCGRGAGDFSEADLADRAFPVRGA 728
            P    +PGL GP  +PG +              P P G   G+         A P    
Sbjct: 314 LPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAG-SKGESGNKGEPGSAGPQGPP 372

Query: 729 GPIAGRRRRRGWTFAAALR--------KGAPREQ-------------PPASPAASPCQAP 767
           GP +G   +RG    A           +G+P  +             PP S  AS     
Sbjct: 373 GP-SGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGV 431

Query: 768 RAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQ-------------PF-PARSRG- 812
           R P  +   P   G    + PR LP +PG  G    +             P  PA +RG 
Sbjct: 432 RGPNGDAGRP---GEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGE 488

Query: 813 ---LGVPSQQGPTGSPGCR-DRASAPRAGAEAGSMETFLRNGGLYPPPSPR 859
              +G P  +GPTG PG   D+  A  AGA          N G   PP P+
Sbjct: 489 PGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPD--GNNGAQGPPGPQ 537



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 120/451 (26%), Positives = 149/451 (33%), Gaps = 56/451 (12%)

Query: 440  RGA--RAGETTPLGEA--RGPCWKARGAVPSGRLRGRPGR--VAGASGRRGASQARGGTG 493
            RGA    G   P G    RG    A  A P+G  RG PG     G +G  G +   G  G
Sbjct: 675  RGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGP-RGSPGERGEVGPAGPNGFAGPAGAAG 733

Query: 494  RAPARLRRG----RGMPGRVG-NGVGEGRGASEPEGEPEPR-ARADLEVLQAGFERLQSL 547
            +  A+  RG    +G  G VG  G     G + P G P P  +R D      G   +   
Sbjct: 734  QPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGD-----GGPPGMTGF 788

Query: 548  PELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSP 607
            P  A R G   P     G+    G    A + GL G    +       ++G      V P
Sbjct: 789  PGAAGRTGPPGPS----GISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGA-----VGP 839

Query: 608  NLRRGSR----RAGNHRVREIEFGSALLAALNTLG-PGSFGAGLGAQGPRSSTPECPVVN 662
                G +     AG            LL A   LG PGS G   G  G   +  E     
Sbjct: 840  PGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGER-GLPGVAGAVGE----- 893

Query: 663  GSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRA 722
                G+A P     G+ G P  + SPG+ G     G    P   G    D       +R 
Sbjct: 894  PGPLGIAGP----PGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERG 949

Query: 723  FPVRGAGPI--AGRRRRRGWTFAAALRKGAPREQPPASPAA-SPCQAPRAPEKETEAPRL 779
            +P    GP+  AG     G     A + G   E  P+ P   +    PR P         
Sbjct: 950  YP-GNIGPVGAAGAPGPHG-PVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGD 1007

Query: 780  RGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTG--------SPGCRD-R 830
            +G      PR LP   G +GL  L          G P   GP G         P  +D R
Sbjct: 1008 KGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGR 1067

Query: 831  ASAPRAGAEAGSMETFLRNGGLYPPPSPRAP 861
               P     AG        G   PP  P  P
Sbjct: 1068 TGHPGTVGPAGIRGPQGHQGPAGPPGPPGPP 1098



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 126/461 (27%), Positives = 153/461 (33%), Gaps = 91/461 (19%)

Query: 462 GAVPSGRLRGRPGRVAGASGRRGASQARGGTG-RAPARLRRGRGMPGRVGN--------- 511
           G +     RG PG + G  G +G +   G  G +  A L   RG PG  GN         
Sbjct: 478 GPIGPAGARGEPGNI-GFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGP 536

Query: 512 -GVGEGRGASEP------EGEPEPRARADLEVLQAGFERLQS---LPELAERLGGRCPG- 560
            GV  G+G   P      +G P P   A  EV + G   L     LP  A   G R P  
Sbjct: 537 QGVQGGKGEQGPPGPPGFQGLPGPSGPAG-EVGKPGERGLHGEFGLPGPAGPRGERGPPG 595

Query: 561 -QVAHGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNH 619
              A G     G    +  PG  G+  +  +  A    G        P+   G R A   
Sbjct: 596 ESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGP-----SGPSGLPGERGAAGI 650

Query: 620 RVREIEFGSALLAALNTLGPGSFGA-----GLGAQGPRSSTPECPVVNGSEWGLAAPLSP 674
              + E G   L       PG  GA      +GA GP  +T +       E G A P  P
Sbjct: 651 PGGKGEKGEPGLRG-EIGNPGRDGARGAPGAVGAPGPAGATGD-----RGEAGAAGPAGP 704

Query: 675 E--RGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCG-RGA-GDFSEADLADRAFPVRGAGP 730
              RGSPG    +   G  G     G    P   G RGA G   E  +     PV  AGP
Sbjct: 705 AGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGP 764

Query: 731 I--------AGRRRRRGWTF-----AAALRKGAPREQ----PPASPAASPCQAPRAPEKE 773
                    AG R   G         AA R G P       PP  P  +  +  R P  +
Sbjct: 765 AGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGD 824

Query: 774 TEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRG-------------LGVPSQQG 820
                  G   AV P      PGF+G    +  P+   G             LG P   G
Sbjct: 825 QGPVGRTGEVGAVGP------PGFAG----EKGPSGEAGTAGPPGTPGPQGLLGAPGILG 874

Query: 821 PTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAP 861
             GS G R       A  E G +       G+  PP  R P
Sbjct: 875 LPGSRGERGLPGVAGAVGEPGPL-------GIAGPPGARGP 908



 Score = 38.5 bits (88), Expect = 0.027
 Identities = 55/199 (27%), Positives = 65/199 (32%), Gaps = 36/199 (18%)

Query: 675 ERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGP---- 730
           ERG PG P      G  GP   PG    P   G  A  +    +     P+   GP    
Sbjct: 43  ERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRGPP 102

Query: 731 -IAGRRRRRGWTFAAALRKGAPREQPPAS---PAASPCQA-----PRAPEKETEAPRLRG 781
             AG    +G+   A    G P +  PA    PA  P +A     P  P +  E    RG
Sbjct: 103 GAAGAPGPQGFQGPAG-EPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGE----RG 157

Query: 782 RATAVAPRPLPAAPGFSGLCVL-----------QPFPARSRGL-------GVPSQQGPTG 823
                  R  P  PG  G   +           QP     +G        G P Q G  G
Sbjct: 158 VVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARG 217

Query: 824 SPGCRDRASAPRAGAEAGS 842
            PG R R  AP      GS
Sbjct: 218 LPGERGRVGAPGPAGARGS 236



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 61/227 (26%), Positives = 75/227 (33%), Gaps = 15/227 (6%)

Query: 637 LGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPV 696
           LGPG  G  +G +GP    P      G + G   P   E G PG+     + G  GP   
Sbjct: 88  LGPGPMGL-MGPRGP----PGAAGAPGPQ-GFQGPAG-EPGEPGQTGPAGARGPAGPPGK 140

Query: 697 PGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALR--KGAPREQ 754
            G    P   GR            R FP  G   + G +  RG      L+   GAP  +
Sbjct: 141 AGEDGHPGKPGRPGERGVVGPQGARGFP--GTPGLPGFKGIRGHNGLDGLKGQPGAPGVK 198

Query: 755 PPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGL- 813
               P A               P  RGR  A  P     + G  G  V    P  S G  
Sbjct: 199 --GEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGP-VGPAGPIGSAGPP 255

Query: 814 GVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRA 860
           G P   GP G  G    A         G +     +G + PP +P A
Sbjct: 256 GFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGA 302



 Score = 30.0 bits (66), Expect = 9.7
 Identities = 28/77 (36%), Positives = 33/77 (42%), Gaps = 21/77 (27%)

Query: 21  PGEKGEKRRTKQIIAAQAGGEGGRAQPGLPCSVDLATGLEGPLGGPAVDLDVGFSPGDDI 80
           PG KGE        A  AG  G R + GLP       GL GP+G P        +PG + 
Sbjct: 261 PGPKGEIGAVGN--AGPAGPAGPRGEVGLP-------GLSGPVGPPG-------NPGANG 304

Query: 81  AGQSLGAAGGQVVHLPG 97
              + GAAG     LPG
Sbjct: 305 LTGAKGAAG-----LPG 316


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score = 63.9 bits (154), Expect = 6e-10
 Identities = 122/445 (27%), Positives = 154/445 (34%), Gaps = 54/445 (12%)

Query: 432  GIEAAVLLRGARAGETTPLGEARGPCWKARGAVPSGRLRGRPGRVAGASGRRGASQARGG 491
            G   A  L+G R    TP  +  GP   +  A P G  +G PG + G  G RGA+   G 
Sbjct: 708  GSPGAQGLQGPRGLPGTPGTD--GPKGASGPAGPPGA-QGPPG-LQGMPGERGAAGIAGP 763

Query: 492  TG-RAPARLRRGRGMPGRVGNGVGEGRGASEPEGEPEPRARADLEVLQAGFERLQSLPEL 550
             G R     +   G PG+ G     GRG + P G P P A A+ E  + G       P  
Sbjct: 764  KGDRGDVGEKGPEGAPGKDG-----GRGLTGPIGPPGP-AGANGEKGEVG------PPGP 811

Query: 551  AERLGGR-CPGQVAHGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNL 609
            A   G R  PG+   G     G    A  PG  G    +     A Q G       +P  
Sbjct: 812  AGSAGARGAPGE--RGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGD----AGAPGP 865

Query: 610  RRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSST-----PECPVVNGS 664
            +  S   G      +        A    G   F    G  GP  S      P  P  +G 
Sbjct: 866  QGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGK 925

Query: 665  EWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGA--GDFSEADLADRA 722
            +    A     RG  G P     PGL GP   PG    P   G     G      LA + 
Sbjct: 926  DGPKGA-----RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ- 979

Query: 723  FPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGR 782
               RG   + G+R  RG+        G P +Q   +P AS  + P  P      P L G 
Sbjct: 980  ---RGIVGLPGQRGERGFPGLPG-PSGEPGKQ--GAPGASGDRGPPGP---VGPPGLTGP 1030

Query: 783  ATAVAPRPLPAA---PGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAE 839
            A        P A   PG  G   ++     +  +G P   GP GSPG            E
Sbjct: 1031 AGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGE 1090

Query: 840  AGSMETFLRNG-----GLYPPPSPR 859
            AG+      +G     G+  P  PR
Sbjct: 1091 AGAQGPMGPSGPAGARGIQGPQGPR 1115



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 104/400 (26%), Positives = 119/400 (29%), Gaps = 59/400 (14%)

Query: 445 GETTPLGEARGPCWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLRRGRG 504
           GE+   GE   P       +P  R R  P   AGA G  G     G  G  P     G G
Sbjct: 309 GESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPG--PVGPAGGPG 366

Query: 505 MPGRVG-NGVGEGRGASEPEGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVA 563
            PG  G  G     GA  PEG   PR          G       P  A   G   PG   
Sbjct: 367 FPGAPGAKGEAGPTGARGPEGAQGPR----------GEPGTPGSPGPAGASGN--PGTDG 414

Query: 564 -HGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVR 622
             G    AG    A  PG  G         A   LG        P  + G       +  
Sbjct: 415 IPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLG--------PKGQTGEPGIAGFKGE 466

Query: 623 EIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP--ERGSPG 680
           +   G          GP       G +G R +          E G   P+ P  ERG+PG
Sbjct: 467 QGPKGEP-----GPAGPQGAPGPAGEEGKRGAR--------GEPGGVGPIGPPGERGAPG 513

Query: 681 RPAFLRSPGLCGPGPVPG-----GLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRR 735
              F    GL GP   PG     GL+ P       G   E  L        GA  + GR 
Sbjct: 514 NRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLP-------GARGLTGRP 566

Query: 736 RRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPR-LRGRATAVAPRPLPAA 794
              G         GAP E     P        +        P+   G       + LP A
Sbjct: 567 GDAG-PQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGA 625

Query: 795 PGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAP 834
           PG  GL      P +    G     GP G  G R    AP
Sbjct: 626 PGLRGL------PGKDGETGAAGPPGPAGPAGERGEQGAP 659



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 107/393 (27%), Positives = 133/393 (33%), Gaps = 65/393 (16%)

Query: 444 AGETTPLGEARGPCWKARGAVPSGR-LRGRPGRVAGASGRRGASQARGGTGR-APARLRR 501
           +G   P G    P       +P  R L GRPG  AG  G+ G S A G  GR  P   + 
Sbjct: 536 SGLAGPKGANGDPGRPGEPGLPGARGLTGRPGD-AGPQGKVGPSGAPGEDGRPGPPGPQG 594

Query: 502 GRGMPGRVGNGVGEGRGASEPEGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQ 561
            RG PG +G       G     GEP           +AG + L   P L           
Sbjct: 595 ARGQPGVMGFP-----GPKGANGEPG----------KAGEKGLPGAPGL----------- 628

Query: 562 VAHGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRV 621
              G+  + G   AA  PG AG   +R     A    G+      P       + G+  V
Sbjct: 629 --RGLPGKDGETGAAGPPGPAGPAGERG-EQGAPGPSGFQGLPGPPGPPGEGGKPGDQGV 685

Query: 622 REIEFGSALLAALNTLG-PGSFGA--GLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGS 678
                   L+      G PG  G+    G QGPR   P  P  +G + G + P  P  G+
Sbjct: 686 PGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG-LPGTPGTDGPK-GASGPAGPP-GA 742

Query: 679 PGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRR 738
            G P     PG  G   + G      P G   GD  E          +G     G+   R
Sbjct: 743 QGPPGLQGMPGERGAAGIAG------PKG-DRGDVGE----------KGPEGAPGKDGGR 785

Query: 739 GWTF-----AAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPA 793
           G T        A   G   E  P  PA S        E+    P   G A    P   P 
Sbjct: 786 GLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPP--GPAGFAGP---PG 840

Query: 794 APGFSGLCVLQPFPARSRGLGVPSQQGPTGSPG 826
           A G  G    Q    +    G P  QGP+G+PG
Sbjct: 841 ADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPG 873



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 119/427 (27%), Positives = 141/427 (33%), Gaps = 73/427 (17%)

Query: 445 GETTPLGEARGPCWKARGAVPSGR-----LRGRPGRVA--GASGRRGASQARGGTG---- 493
           GE  P GE  GP        P+G       RG PG V   G  G RGA   RG  G    
Sbjct: 465 GEQGPKGEP-GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGL 523

Query: 494 ---------RAPARL---RRGRGMPGRVGN-GVGEGRGASEPEGEPEPRARADLEVLQAG 540
                    R P+ L   +   G PGR G  G+   RG +   G+  P+ +    V  +G
Sbjct: 524 AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGK----VGPSG 579

Query: 541 FERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAGS-GVQRALALAAAQLGG 599
                  P      G R  GQ   GV+   G   A   PG AG  G+  A  L       
Sbjct: 580 APGEDGRPGPPGPQGAR--GQP--GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKD 635

Query: 600 WTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECP 659
             T    P    G   AG    +     S         GP   G   G QG        P
Sbjct: 636 GETGAAGPPGPAGP--AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQG-------VP 686

Query: 660 VVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLA 719
              G+  GL  P   ERG PG      + GL GP  +PG      P G            
Sbjct: 687 GEAGAP-GLVGPRG-ERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGP-------- 736

Query: 720 DRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETE-APR 778
             A P    GP                 +G P E+  A  A          EK  E AP 
Sbjct: 737 --AGPPGAQGPPG--------------LQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG 780

Query: 779 LRGRATAVAPRPLPAAPGFSGLC--VLQPFPARSRGL-GVPSQQGPTGSPGCRDRASAPR 835
             G      P   P   G +G    V  P PA S G  G P ++G TG PG    A  P 
Sbjct: 781 KDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPG 840

Query: 836 AGAEAGS 842
           A  + G+
Sbjct: 841 ADGQPGA 847



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 113/432 (26%), Positives = 144/432 (33%), Gaps = 61/432 (14%)

Query: 465 PSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLRRG----RGMPGRVGNGVGEGR-GA 519
           P G+ +G PG +    G +G    +G  G    R  RG    +G PG  G     G  G 
Sbjct: 102 PKGQ-KGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGN 160

Query: 520 SEPEGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARP 579
             P G P P     L     G    Q      E+ GG   G V  G +   G +     P
Sbjct: 161 PGPPGPPGPPGPPGL----GGNFAAQMAGGFDEKAGGAQLG-VMQGPM---GPMGPRGPP 212

Query: 580 GLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGP 639
           G AG+   +       + G     V  P   RG          + E G           P
Sbjct: 213 GPAGAPGPQGFQGNPGEPG--EPGVSGPMGPRGPPGPPGKPGDDGEAGK----------P 260

Query: 640 GSFG--AGLGAQGPRS--STPECPVV---------NGSEWGLAAP-LSPERGSPGRPAFL 685
           G  G     G QG R    TP  P V         +G++    AP +  E GSPG     
Sbjct: 261 GKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENG-- 318

Query: 686 RSPGLCGPGPVPG--GLSVPTPCGRGAGDFSEADLADRAFPVRGAG----PIAGRRRRRG 739
            SPG  GP  +PG  G + P       G+  +   A    PV  AG    P A   +   
Sbjct: 319 -SPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEA 377

Query: 740 WTFAAALRKGA--PREQPPASPAASPCQAPRAPEKE--------TEAPRLRGRATAVAPR 789
               A   +GA  PR +P    +  P  A   P  +          AP + G      PR
Sbjct: 378 GPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPR 437

Query: 790 PLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRN 849
             P   G +G    +         G   +QGP G PG      AP    E G        
Sbjct: 438 GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEP 497

Query: 850 GGLYP--PPSPR 859
           GG+ P  PP  R
Sbjct: 498 GGVGPIGPPGER 509



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 105/399 (26%), Positives = 124/399 (31%), Gaps = 126/399 (31%)

Query: 470 RGRPGRVAGASGRRGASQARGGTGRAPARLRRGR-GMPGRVGNGVGEGRGASEPEGEPEP 528
           +G PG   G +G +G    RG  G   A   RGR G PG  GN      G   P G P P
Sbjct: 119 KGPPGP-QGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNP-----GPPGPPGPPGP 172

Query: 529 RARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAGSGVQR 588
                                    LGG    Q+A G   +AG                 
Sbjct: 173 PG-----------------------LGGNFAAQMAGGFDEKAG----------------- 192

Query: 589 ALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGA 648
                 AQLG                               +   +  +GP       GA
Sbjct: 193 -----GAQLG------------------------------VMQGPMGPMGPRGPPGPAGA 217

Query: 649 QGPRS--STPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPC 706
            GP+     P  P     E G++ P+ P RG PG P     PG  G    PG      P 
Sbjct: 218 PGPQGFQGNPGEP----GEPGVSGPMGP-RGPPGPPG---KPGDDGEAGKPGKAGERGPP 269

Query: 707 G-RGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTF--AAALRKGAPREQPPA-SPAAS 762
           G +GA          R FP  G   + G +  RG+     A    GAP  +  + SP  +
Sbjct: 270 GPQGA----------RGFP--GTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN 317

Query: 763 PCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPT 822
               P  P      P  RGR     P     A G  G    QP PA     G P   GP 
Sbjct: 318 GSPGPMGPRG---LPGERGRT---GPAGAAGARGNDG----QPGPA-----GPPGPVGPA 362

Query: 823 GSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAP 861
           G PG      AP A  EAG        G   P   P  P
Sbjct: 363 GGPGF---PGAPGAKGEAGPTGARGPEGAQGPRGEPGTP 398



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 57/190 (30%), Positives = 68/190 (35%), Gaps = 17/190 (8%)

Query: 645  GLGAQGPRSSTPECPVVNGSEWGLAAP-LSPERGSPGRPAFLRSPGLCGPGPVPGGLSVP 703
            GL  Q      P  P  +G      AP  S +RG PG    +  PGL GP   PG    P
Sbjct: 984  GLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGP---VGPPGLTGPAGEPGREGSP 1040

Query: 704  TPCGRGAGDFSEADLADR----AFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQP--PA 757
               G    D +     DR    A    GA    G     G T     R  A  + P  P+
Sbjct: 1041 GADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPS 1100

Query: 758  SPA-ASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVP 816
             PA A   Q P+ P  +      +G A     R L    GF+GL  L   P  S   G  
Sbjct: 1101 GPAGARGIQGPQGPRGD------KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGAS 1154

Query: 817  SQQGPTGSPG 826
               GP+G  G
Sbjct: 1155 GPAGPSGPRG 1164



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 93/366 (25%), Positives = 123/366 (33%), Gaps = 43/366 (11%)

Query: 440  RGARAGETTPLGEARGPCWKARGAVPSGRLRGRPGR-----VAGASGRRGASQARGGTGR 494
            +GAR G++ P G A  P  +     P  +  G PG        G  G +G +  RG  G 
Sbjct: 929  KGAR-GDSGPPGRAGEPGLQGPAGPPGEK--GEPGDDGPSGAEGPPGPQGLAGQRGIVGL 985

Query: 495  APARLRRG-RGMPGRVGNGVGEGR-GASEPEGEPEPRARADLEVLQAGFERLQSLPELAE 552
               R  RG  G+PG  G    +G  GAS   G P P     L    AG    +  P  A+
Sbjct: 986  PGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTG-PAGEPGREGSPG-AD 1043

Query: 553  RLGGRCPGQVAHGVLARAGLLAAAARPGLAGS-------GVQRALALAAAQ--LG----G 599
               GR       G     G + A   PG  GS       G Q     A AQ  +G     
Sbjct: 1044 GPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPA 1103

Query: 600  WTTCVVSPNLRRGSR-RAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSST--- 655
                +  P   RG +  AG    R ++            GP       GA GP   +   
Sbjct: 1104 GARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPR 1163

Query: 656  ----PECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAG 711
                P  P       G+  P+ P    PG        G  GP   PG    P P G G  
Sbjct: 1164 GPPGPVGPSGKDGANGIPGPIGP----PGPRGRSGETGPAGPPGNPGPPGPPGPPGPGID 1219

Query: 712  DFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPE 771
              + A L  R    +G  P+   R  +    A  LR+             +  ++ R+PE
Sbjct: 1220 MSAFAGLGPRE---KGPDPLQYMRADQA---AGGLRQHDAEVDATLKSLNNQIESIRSPE 1273

Query: 772  KETEAP 777
               + P
Sbjct: 1274 GSRKNP 1279



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 98/355 (27%), Positives = 120/355 (33%), Gaps = 55/355 (15%)

Query: 440  RGARAGETTPLGEARGPCWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTGRAPAR- 498
            +GAR  +  P G    P    R   P       P    G SG+ G   ARG +G  P R 
Sbjct: 884  KGARGAQGPP-GATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSG-PPGRA 941

Query: 499  ----LRRGRGMPGRVGNGVGEGRGASEPEGEPEPRARADLEVL-----QAGFERLQSLPE 549
                L+   G PG  G    +G   S  EG P P+  A    +     Q G      LP 
Sbjct: 942  GEPGLQGPAGPPGEKGEPGDDG--PSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPG 999

Query: 550  LAERLGGR-CPGQVAH----GVLARAGLLAAAARPGLAGS-------GVQRALALAAAQL 597
             +   G +  PG        G +   GL   A  PG  GS       G   A  +   + 
Sbjct: 1000 PSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDR- 1058

Query: 598  GGWTTCVVSPNLRR--GSRRAGNHRVREIEFGSALLAALNTLGP-GSFGA-GL-GAQGPR 652
             G T  V +P      GS        ++ + G A   A   +GP G  GA G+ G QGPR
Sbjct: 1059 -GETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEA--GAQGPMGPSGPAGARGIQGPQGPR 1115

Query: 653  SSTPECPVVNGSEWGLAAP--LSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGA 710
                E       E GL      +  +G PG P      G  GP    G    P P G   
Sbjct: 1116 GDKGEAG--EPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSG 1173

Query: 711  GDFSEADLADRAFPVRGAGPIA--GRRRRRGWTFAAALRKGAPREQPPASPAASP 763
             D +              GPI   G R R G T  A    G P    P  P   P
Sbjct: 1174 KDGANGI----------PGPIGPPGPRGRSGETGPA----GPPGNPGPPGPPGPP 1214



 Score = 34.7 bits (78), Expect = 0.39
 Identities = 50/165 (30%), Positives = 60/165 (36%), Gaps = 38/165 (23%)

Query: 17  PRFIPGEKGEKRRTKQIIAAQAGGEGGRAQPGLPCSVDLATGLEGPLGGPAVDLDVGF-- 74
           PR +PGE+G   RT    AA A G  G+  P  P       G  GP GGP      GF  
Sbjct: 325 PRGLPGERG---RTGPAGAAGARGNDGQPGPAGP------PGPVGPAGGP------GFPG 369

Query: 75  SPGDDIAGQSLGAAGGQVVHLPGGQLAVPDVEVGQLTHKCLGGIKPTTQSYLLLAQHQHA 134
           +PG        GA G +    P G+   P            G   P   S          
Sbjct: 370 APGAKGEAGPTGARGPEGAQGPRGEPGTP------------GSPGPAGAS--------GN 409

Query: 135 LGLDGVIGRQVLATATLRAILVGLPDP-VPGGPVYTTSPSLHQGE 178
            G DG+ G +  A A   A   G P P  P GP   T P   +G+
Sbjct: 410 PGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQ 454


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score = 63.9 bits (154), Expect = 6e-10
 Identities = 122/445 (27%), Positives = 154/445 (34%), Gaps = 54/445 (12%)

Query: 432  GIEAAVLLRGARAGETTPLGEARGPCWKARGAVPSGRLRGRPGRVAGASGRRGASQARGG 491
            G   A  L+G R    TP  +  GP   +  A P G  +G PG + G  G RGA+   G 
Sbjct: 639  GSPGAQGLQGPRGLPGTPGTD--GPKGASGPAGPPGA-QGPPG-LQGMPGERGAAGIAGP 694

Query: 492  TG-RAPARLRRGRGMPGRVGNGVGEGRGASEPEGEPEPRARADLEVLQAGFERLQSLPEL 550
             G R     +   G PG+ G     GRG + P G P P A A+ E  + G       P  
Sbjct: 695  KGDRGDVGEKGPEGAPGKDG-----GRGLTGPIGPPGP-AGANGEKGEVG------PPGP 742

Query: 551  AERLGGR-CPGQVAHGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNL 609
            A   G R  PG+   G     G    A  PG  G    +     A Q G       +P  
Sbjct: 743  AGSAGARGAPGE--RGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGD----AGAPGP 796

Query: 610  RRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSST-----PECPVVNGS 664
            +  S   G      +        A    G   F    G  GP  S      P  P  +G 
Sbjct: 797  QGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGK 856

Query: 665  EWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGA--GDFSEADLADRA 722
            +    A     RG  G P     PGL GP   PG    P   G     G      LA + 
Sbjct: 857  DGPKGA-----RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ- 910

Query: 723  FPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGR 782
               RG   + G+R  RG+        G P +Q   +P AS  + P  P      P L G 
Sbjct: 911  ---RGIVGLPGQRGERGFPGLPG-PSGEPGKQ--GAPGASGDRGPPGP---VGPPGLTGP 961

Query: 783  ATAVAPRPLPAA---PGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAE 839
            A        P A   PG  G   ++     +  +G P   GP GSPG            E
Sbjct: 962  AGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGE 1021

Query: 840  AGSMETFLRNG-----GLYPPPSPR 859
            AG+      +G     G+  P  PR
Sbjct: 1022 AGAQGPMGPSGPAGARGIQGPQGPR 1046



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 104/400 (26%), Positives = 119/400 (29%), Gaps = 59/400 (14%)

Query: 445 GETTPLGEARGPCWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLRRGRG 504
           GE+   GE   P       +P  R R  P   AGA G  G     G  G  P     G G
Sbjct: 240 GESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPG--PVGPAGGPG 297

Query: 505 MPGRVG-NGVGEGRGASEPEGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVA 563
            PG  G  G     GA  PEG   PR          G       P  A   G   PG   
Sbjct: 298 FPGAPGAKGEAGPTGARGPEGAQGPR----------GEPGTPGSPGPAGASGN--PGTDG 345

Query: 564 -HGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVR 622
             G    AG    A  PG  G         A   LG        P  + G       +  
Sbjct: 346 IPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLG--------PKGQTGEPGIAGFKGE 397

Query: 623 EIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP--ERGSPG 680
           +   G          GP       G +G R +          E G   P+ P  ERG+PG
Sbjct: 398 QGPKGEP-----GPAGPQGAPGPAGEEGKRGAR--------GEPGGVGPIGPPGERGAPG 444

Query: 681 RPAFLRSPGLCGPGPVPG-----GLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRR 735
              F    GL GP   PG     GL+ P       G   E  L        GA  + GR 
Sbjct: 445 NRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLP-------GARGLTGRP 497

Query: 736 RRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPR-LRGRATAVAPRPLPAA 794
              G         GAP E     P        +        P+   G       + LP A
Sbjct: 498 GDAG-PQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGA 556

Query: 795 PGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAP 834
           PG  GL      P +    G     GP G  G R    AP
Sbjct: 557 PGLRGL------PGKDGETGAAGPPGPAGPAGERGEQGAP 590



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 107/393 (27%), Positives = 133/393 (33%), Gaps = 65/393 (16%)

Query: 444 AGETTPLGEARGPCWKARGAVPSGR-LRGRPGRVAGASGRRGASQARGGTGR-APARLRR 501
           +G   P G    P       +P  R L GRPG  AG  G+ G S A G  GR  P   + 
Sbjct: 467 SGLAGPKGANGDPGRPGEPGLPGARGLTGRPGD-AGPQGKVGPSGAPGEDGRPGPPGPQG 525

Query: 502 GRGMPGRVGNGVGEGRGASEPEGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQ 561
            RG PG +G       G     GEP           +AG + L   P L           
Sbjct: 526 ARGQPGVMGFP-----GPKGANGEPG----------KAGEKGLPGAPGL----------- 559

Query: 562 VAHGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRV 621
              G+  + G   AA  PG AG   +R     A    G+      P       + G+  V
Sbjct: 560 --RGLPGKDGETGAAGPPGPAGPAGERG-EQGAPGPSGFQGLPGPPGPPGEGGKPGDQGV 616

Query: 622 REIEFGSALLAALNTLG-PGSFGA--GLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGS 678
                   L+      G PG  G+    G QGPR   P  P  +G + G + P  P  G+
Sbjct: 617 PGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG-LPGTPGTDGPK-GASGPAGPP-GA 673

Query: 679 PGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRR 738
            G P     PG  G   + G      P G   GD  E          +G     G+   R
Sbjct: 674 QGPPGLQGMPGERGAAGIAG------PKG-DRGDVGE----------KGPEGAPGKDGGR 716

Query: 739 GWTF-----AAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPA 793
           G T        A   G   E  P  PA S        E+    P   G A    P   P 
Sbjct: 717 GLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPP--GPAGFAGP---PG 771

Query: 794 APGFSGLCVLQPFPARSRGLGVPSQQGPTGSPG 826
           A G  G    Q    +    G P  QGP+G+PG
Sbjct: 772 ADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPG 804



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 119/427 (27%), Positives = 141/427 (33%), Gaps = 73/427 (17%)

Query: 445 GETTPLGEARGPCWKARGAVPSGR-----LRGRPGRVA--GASGRRGASQARGGTG---- 493
           GE  P GE  GP        P+G       RG PG V   G  G RGA   RG  G    
Sbjct: 396 GEQGPKGEP-GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGL 454

Query: 494 ---------RAPARL---RRGRGMPGRVGN-GVGEGRGASEPEGEPEPRARADLEVLQAG 540
                    R P+ L   +   G PGR G  G+   RG +   G+  P+ +    V  +G
Sbjct: 455 AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGK----VGPSG 510

Query: 541 FERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAGS-GVQRALALAAAQLGG 599
                  P      G R  GQ   GV+   G   A   PG AG  G+  A  L       
Sbjct: 511 APGEDGRPGPPGPQGAR--GQP--GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKD 566

Query: 600 WTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECP 659
             T    P    G   AG    +     S         GP   G   G QG        P
Sbjct: 567 GETGAAGPPGPAGP--AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQG-------VP 617

Query: 660 VVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLA 719
              G+  GL  P   ERG PG      + GL GP  +PG      P G            
Sbjct: 618 GEAGAP-GLVGPRG-ERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGP-------- 667

Query: 720 DRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETE-APR 778
             A P    GP                 +G P E+  A  A          EK  E AP 
Sbjct: 668 --AGPPGAQGPPG--------------LQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG 711

Query: 779 LRGRATAVAPRPLPAAPGFSGLC--VLQPFPARSRGL-GVPSQQGPTGSPGCRDRASAPR 835
             G      P   P   G +G    V  P PA S G  G P ++G TG PG    A  P 
Sbjct: 712 KDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPG 771

Query: 836 AGAEAGS 842
           A  + G+
Sbjct: 772 ADGQPGA 778



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 113/432 (26%), Positives = 144/432 (33%), Gaps = 61/432 (14%)

Query: 465 PSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLRRG----RGMPGRVGNGVGEGR-GA 519
           P G+ +G PG +    G +G    +G  G    R  RG    +G PG  G     G  G 
Sbjct: 33  PKGQ-KGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGN 91

Query: 520 SEPEGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARP 579
             P G P P     L     G    Q      E+ GG   G V  G +   G +     P
Sbjct: 92  PGPPGPPGPPGPPGL----GGNFAAQMAGGFDEKAGGAQLG-VMQGPM---GPMGPRGPP 143

Query: 580 GLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGP 639
           G AG+   +       + G     V  P   RG          + E G           P
Sbjct: 144 GPAGAPGPQGFQGNPGEPG--EPGVSGPMGPRGPPGPPGKPGDDGEAGK----------P 191

Query: 640 GSFG--AGLGAQGPRS--STPECPVV---------NGSEWGLAAP-LSPERGSPGRPAFL 685
           G  G     G QG R    TP  P V         +G++    AP +  E GSPG     
Sbjct: 192 GKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENG-- 249

Query: 686 RSPGLCGPGPVPG--GLSVPTPCGRGAGDFSEADLADRAFPVRGAG----PIAGRRRRRG 739
            SPG  GP  +PG  G + P       G+  +   A    PV  AG    P A   +   
Sbjct: 250 -SPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEA 308

Query: 740 WTFAAALRKGA--PREQPPASPAASPCQAPRAPEKE--------TEAPRLRGRATAVAPR 789
               A   +GA  PR +P    +  P  A   P  +          AP + G      PR
Sbjct: 309 GPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPR 368

Query: 790 PLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRN 849
             P   G +G    +         G   +QGP G PG      AP    E G        
Sbjct: 369 GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEP 428

Query: 850 GGLYP--PPSPR 859
           GG+ P  PP  R
Sbjct: 429 GGVGPIGPPGER 440



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 105/399 (26%), Positives = 124/399 (31%), Gaps = 126/399 (31%)

Query: 470 RGRPGRVAGASGRRGASQARGGTGRAPARLRRGR-GMPGRVGNGVGEGRGASEPEGEPEP 528
           +G PG   G +G +G    RG  G   A   RGR G PG  GN      G   P G P P
Sbjct: 50  KGPPGP-QGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNP-----GPPGPPGPPGP 103

Query: 529 RARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAGSGVQR 588
                                    LGG    Q+A G   +AG                 
Sbjct: 104 PG-----------------------LGGNFAAQMAGGFDEKAG----------------- 123

Query: 589 ALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGA 648
                 AQLG                               +   +  +GP       GA
Sbjct: 124 -----GAQLG------------------------------VMQGPMGPMGPRGPPGPAGA 148

Query: 649 QGPRS--STPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPC 706
            GP+     P  P     E G++ P+ P RG PG P     PG  G    PG      P 
Sbjct: 149 PGPQGFQGNPGEP----GEPGVSGPMGP-RGPPGPPG---KPGDDGEAGKPGKAGERGPP 200

Query: 707 G-RGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTF--AAALRKGAPREQPPA-SPAAS 762
           G +GA          R FP  G   + G +  RG+     A    GAP  +  + SP  +
Sbjct: 201 GPQGA----------RGFP--GTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN 248

Query: 763 PCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPT 822
               P  P      P  RGR     P     A G  G    QP PA     G P   GP 
Sbjct: 249 GSPGPMGPRG---LPGERGRT---GPAGAAGARGNDG----QPGPA-----GPPGPVGPA 293

Query: 823 GSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAP 861
           G PG      AP A  EAG        G   P   P  P
Sbjct: 294 GGPGF---PGAPGAKGEAGPTGARGPEGAQGPRGEPGTP 329



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 57/190 (30%), Positives = 68/190 (35%), Gaps = 17/190 (8%)

Query: 645  GLGAQGPRSSTPECPVVNGSEWGLAAP-LSPERGSPGRPAFLRSPGLCGPGPVPGGLSVP 703
            GL  Q      P  P  +G      AP  S +RG PG    +  PGL GP   PG    P
Sbjct: 915  GLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGP---VGPPGLTGPAGEPGREGSP 971

Query: 704  TPCGRGAGDFSEADLADR----AFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQP--PA 757
               G    D +     DR    A    GA    G     G T     R  A  + P  P+
Sbjct: 972  GADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPS 1031

Query: 758  SPA-ASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVP 816
             PA A   Q P+ P  +      +G A     R L    GF+GL  L   P  S   G  
Sbjct: 1032 GPAGARGIQGPQGPRGD------KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGAS 1085

Query: 817  SQQGPTGSPG 826
               GP+G  G
Sbjct: 1086 GPAGPSGPRG 1095



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 93/366 (25%), Positives = 123/366 (33%), Gaps = 43/366 (11%)

Query: 440  RGARAGETTPLGEARGPCWKARGAVPSGRLRGRPGR-----VAGASGRRGASQARGGTGR 494
            +GAR G++ P G A  P  +     P  +  G PG        G  G +G +  RG  G 
Sbjct: 860  KGAR-GDSGPPGRAGEPGLQGPAGPPGEK--GEPGDDGPSGAEGPPGPQGLAGQRGIVGL 916

Query: 495  APARLRRG-RGMPGRVGNGVGEGR-GASEPEGEPEPRARADLEVLQAGFERLQSLPELAE 552
               R  RG  G+PG  G    +G  GAS   G P P     L    AG    +  P  A+
Sbjct: 917  PGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTG-PAGEPGREGSPG-AD 974

Query: 553  RLGGRCPGQVAHGVLARAGLLAAAARPGLAGS-------GVQRALALAAAQ--LG----G 599
               GR       G     G + A   PG  GS       G Q     A AQ  +G     
Sbjct: 975  GPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPA 1034

Query: 600  WTTCVVSPNLRRGSR-RAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSST--- 655
                +  P   RG +  AG    R ++            GP       GA GP   +   
Sbjct: 1035 GARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPR 1094

Query: 656  ----PECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAG 711
                P  P       G+  P+ P    PG        G  GP   PG    P P G G  
Sbjct: 1095 GPPGPVGPSGKDGANGIPGPIGP----PGPRGRSGETGPAGPPGNPGPPGPPGPPGPGID 1150

Query: 712  DFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPE 771
              + A L  R    +G  P+   R  +    A  LR+             +  ++ R+PE
Sbjct: 1151 MSAFAGLGPRE---KGPDPLQYMRADQA---AGGLRQHDAEVDATLKSLNNQIESIRSPE 1204

Query: 772  KETEAP 777
               + P
Sbjct: 1205 GSRKNP 1210



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 98/355 (27%), Positives = 120/355 (33%), Gaps = 55/355 (15%)

Query: 440  RGARAGETTPLGEARGPCWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTGRAPAR- 498
            +GAR  +  P G    P    R   P       P    G SG+ G   ARG +G  P R 
Sbjct: 815  KGARGAQGPP-GATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSG-PPGRA 872

Query: 499  ----LRRGRGMPGRVGNGVGEGRGASEPEGEPEPRARADLEVL-----QAGFERLQSLPE 549
                L+   G PG  G    +G   S  EG P P+  A    +     Q G      LP 
Sbjct: 873  GEPGLQGPAGPPGEKGEPGDDG--PSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPG 930

Query: 550  LAERLGGR-CPGQVAH----GVLARAGLLAAAARPGLAGS-------GVQRALALAAAQL 597
             +   G +  PG        G +   GL   A  PG  GS       G   A  +   + 
Sbjct: 931  PSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDR- 989

Query: 598  GGWTTCVVSPNLRR--GSRRAGNHRVREIEFGSALLAALNTLGP-GSFGA-GL-GAQGPR 652
             G T  V +P      GS        ++ + G A   A   +GP G  GA G+ G QGPR
Sbjct: 990  -GETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEA--GAQGPMGPSGPAGARGIQGPQGPR 1046

Query: 653  SSTPECPVVNGSEWGLAAP--LSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGA 710
                E       E GL      +  +G PG P      G  GP    G    P P G   
Sbjct: 1047 GDKGEAG--EPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSG 1104

Query: 711  GDFSEADLADRAFPVRGAGPIA--GRRRRRGWTFAAALRKGAPREQPPASPAASP 763
             D +              GPI   G R R G T  A    G P    P  P   P
Sbjct: 1105 KDGANGI----------PGPIGPPGPRGRSGETGPA----GPPGNPGPPGPPGPP 1145



 Score = 34.7 bits (78), Expect = 0.39
 Identities = 50/165 (30%), Positives = 60/165 (36%), Gaps = 38/165 (23%)

Query: 17  PRFIPGEKGEKRRTKQIIAAQAGGEGGRAQPGLPCSVDLATGLEGPLGGPAVDLDVGF-- 74
           PR +PGE+G   RT    AA A G  G+  P  P       G  GP GGP      GF  
Sbjct: 256 PRGLPGERG---RTGPAGAAGARGNDGQPGPAGP------PGPVGPAGGP------GFPG 300

Query: 75  SPGDDIAGQSLGAAGGQVVHLPGGQLAVPDVEVGQLTHKCLGGIKPTTQSYLLLAQHQHA 134
           +PG        GA G +    P G+   P            G   P   S          
Sbjct: 301 APGAKGEAGPTGARGPEGAQGPRGEPGTP------------GSPGPAGAS--------GN 340

Query: 135 LGLDGVIGRQVLATATLRAILVGLPDP-VPGGPVYTTSPSLHQGE 178
            G DG+ G +  A A   A   G P P  P GP   T P   +G+
Sbjct: 341 PGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQ 385


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 111/402 (27%), Positives = 139/402 (34%), Gaps = 39/402 (9%)

Query: 445  GETTPLGEARGPCWK-ARGAVPSGRLRGRPGRVA--GASGRRGASQARGGTGR-APARLR 500
            G   P G    P +  A G   +  + G+PG     G +G RG+  ARG TG+  P    
Sbjct: 859  GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS 918

Query: 501  RGRGMPGRVGNGVGEGR----GASEPEGEPEPRARADLEVLQAGFERLQSLPELAERLGG 556
             G G PG  G    +G     G   P+G P P  +  L     G    +       + G 
Sbjct: 919  GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLP----GHPGQRGETGFQGKTGP 974

Query: 557  RCPGQVA--HGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSR 614
              PG V    G     G +     PG  G   ++ L  AA + G        P  +  S 
Sbjct: 975  PGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKG----DPGPQGISG 1030

Query: 615  RAGNHRVREIEFGSALLAALNTLGPGSFGA-GL-GAQGPRSSTPECPVVNGSEWGLAAPL 672
            + G   +R       L        PG+ GA GL G +GP+   P  PV +  E G A   
Sbjct: 1031 KDGPAGLRGFPGERGL--------PGAQGAPGLKGGEGPQG--PPGPVGSPGERGSAGTA 1080

Query: 673  SPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIA 732
             P  G PGRP     PG  G    PG      P GR  G      L   A P    G   
Sbjct: 1081 GPI-GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD-GVQGPVGLPGPAGPAGSPGE-D 1137

Query: 733  GRRRRRGWTFAAALRKGAPREQPPASPAAS-PCQAPRAPEKETE-APR----LRGRATAV 786
            G +   G       +       PP  P    P  AP     + E  PR    + G+    
Sbjct: 1138 GDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDE 1197

Query: 787  APRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCR 828
              R  P  PG  GL  L   P      G     GP G PG R
Sbjct: 1198 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1239



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 100/404 (24%), Positives = 132/404 (32%), Gaps = 77/404 (19%)

Query: 473  PGRVAGASGRRGASQARGGTG-------RAPARLRRGRGMPGRVGNGVGEG----RGASE 521
            P  V GA G RG   ++G  G       +    L+  RG  G++G    +G    +G + 
Sbjct: 773  PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAG 832

Query: 522  PEGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGL 581
            P G+P P         QAG +    +P L              G   R G   +   PG 
Sbjct: 833  PTGDPGPSG-------QAGEKGKLGVPGLP-------------GYPGRQGPKGSTGFPGF 872

Query: 582  AGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGS 641
             G+  ++     A + G        P  +RG       R      G          GP  
Sbjct: 873  PGANGEKGARGVAGKPG--------PRGQRGPTGPRGSRGARGPTGKP--------GPKG 916

Query: 642  FGAGLGAQGPRSST----PECPVVNGSEWGLAAPLSPER--GSPGRPAFLRSPGLCGPGP 695
               G G  GP        P+ PV      G   P   +   G PG+       G  GP P
Sbjct: 917  TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP-P 975

Query: 696  VPGGLSVPT-------PCGRGAGDFSEADLADRAFP----VRGAGPIAGRRRRRGWTFAA 744
             PGG+  P        P G            ++  P      GA    G +   G    A
Sbjct: 976  GPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPA 1035

Query: 745  ALR-----KGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSG 799
             LR     +G P  Q   +P     + P+ P     +P  RG A    P  LP  PG  G
Sbjct: 1036 GLRGFPGERGLPGAQ--GAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQG 1093

Query: 800  LCVLQPFPARSRGL-GVPSQQGPTGSPGCRDRASAPRAGAEAGS 842
                 P PA  +G  G    QGP G  G +     P     AGS
Sbjct: 1094 ----PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1133



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 115/435 (26%), Positives = 148/435 (34%), Gaps = 92/435 (21%)

Query: 469 LRGRPGRVAGASGRRGASQARGGTGRAPARLRRG-RGMPGRVGNGVGEGR-GASEPEGEP 526
           L GRPG V G     G+S A+G +G    +  RG +G PG  G     GR GA    G P
Sbjct: 548 LTGRPGPVGGP----GSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMP 603

Query: 527 -EPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVA-----HGVLARAGLLAAAARPG 580
            EP A+ D      GF+ L  LP      G R P          G+    G +     PG
Sbjct: 604 GEPGAKGD-----RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPG 658

Query: 581 LAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPG 640
            AG    R L              + P   RG+  A          G   +A ++  GP 
Sbjct: 659 EAGP---RGL--------------LGP---RGTPGAP---------GQPGMAGVD--GPP 687

Query: 641 SFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP-----ERGSPGRPAFLRSPGLCGPGP 695
                +G QG     P     N    GL  P  P     E+G  G+P     PG  GP  
Sbjct: 688 GPKGNMGPQGEPG--PPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPG 745

Query: 696 VPGG------------------LSVPTPCGRGAGD------FSEADLADRAFP-VRGAGP 730
            PG                   +  P P G    D       S+ +  +  FP  +G   
Sbjct: 746 HPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG 805

Query: 731 IAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEK-ETEAPRLRGRATAVAPR 789
           + G R   G         G    +  A P   P  + +A EK +   P L G      P+
Sbjct: 806 LKGDRGEVG-QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 864

Query: 790 PLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRD-RASAPRAGAEAGSMETFLR 848
                PGF G    +     +   G   Q+GPTG  G R  R    + G +  S      
Sbjct: 865 GSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS------ 918

Query: 849 NGGLYP--PPSPRAP 861
            GG  P  PP  R P
Sbjct: 919 -GGDGPPGPPGERGP 932



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 61/208 (29%), Positives = 75/208 (36%), Gaps = 33/208 (15%)

Query: 639 PGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP-----ERGSPGRPAFLRSPGLCGP 693
           P     G+  +GP    P  P       GL  P  P     +RG PGRP    + GL  P
Sbjct: 443 PAVVEPGMLVEGPPG--PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGL--P 498

Query: 694 GPVPGGLSVPTPCGRGAGDFS------------EADLADRAFPVRG-AGP--IAGRRRRR 738
           GP    L +P    R  GD S            +A L      +RG  GP  + GR    
Sbjct: 499 GPPGTMLMLPF---RYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPV 555

Query: 739 GWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFS 798
           G   ++   KG   +  P  P     Q P  P   T  P  RGR  A   R +P  PG  
Sbjct: 556 GGPGSSG-AKGESGDPGPQGPRG--VQGPPGP---TGKPGKRGRPGADGGRGMPGEPGAK 609

Query: 799 GLCVLQPFPARSRGLGVPSQQGPTGSPG 826
           G       P      G   ++GP G PG
Sbjct: 610 GDRGFDGLPGLPGDKGHRGERGPQGPPG 637



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 100/402 (24%), Positives = 126/402 (31%), Gaps = 80/402 (19%)

Query: 469 LRGRPGRVA-----GASGRRGASQARGGTGRAPARLRRGRGMPGRVG-NGVGEGRGASEP 522
           +RG  G +      G +G RG    RG  G AP       G PG  G +G    +G   P
Sbjct: 644 MRGEDGEIGPRGLPGEAGPRGLLGPRGTPG-AP-------GQPGMAGVDGPPGPKGNMGP 695

Query: 523 EGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVA-HGVLARAGLLAAAARPGL 581
           +GEP P         Q G    Q LP     +G   PG+    G    AGL  A   PG 
Sbjct: 696 QGEPGPPG-------QQGNPGPQGLPGPQGPIGP--PGEKGPQGKPGLAGLPGADGPPGH 746

Query: 582 AGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGS 641
            G   Q           G    +  P  +      G   V+  +    L  +    G   
Sbjct: 747 PGKEGQ----------SGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDG 796

Query: 642 FGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLS 701
           F    G  G +    E   +     G      PE G  GR      PG  G     G L 
Sbjct: 797 FPGFKGDMGLKGDRGEVGQI-----GPRGEDGPE-GPKGRAGPTGDPGPSGQAGEKGKLG 850

Query: 702 VPTPCGRGAGDFSEADLADRAFP----VRGAGPIAGRRRRRGWTFAAALRKGAPREQPPA 757
           VP   G       +       FP     +GA  +AG+   RG             ++ P 
Sbjct: 851 VPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRG-------------QRGPT 897

Query: 758 SPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRG-LGVP 816
            P  S     R     T  P  +G +    P   P  PG  G       P   +G +G P
Sbjct: 898 GPRGS-----RGARGPTGKPGPKGTSGGDGP---PGPPGERG-------PQGPQGPVGFP 942

Query: 817 SQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSP 858
             +GP G PG       P    E G         G   PP P
Sbjct: 943 GPKGPPGPPGKDGLPGHPGQRGETGFQ-------GKTGPPGP 977



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 124/460 (26%), Positives = 158/460 (34%), Gaps = 76/460 (16%)

Query: 445  GETTPLGEARGPCWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTGR-APARLRR-- 501
            GET P+GE   P        P G  +G PG  AG  G +G    +G +G+  PA LR   
Sbjct: 988  GETGPIGERGHPGPPG----PPGE-QGLPG-AAGKEGAKGDPGPQGISGKDGPAGLRGFP 1041

Query: 502  -GRGMPGRVGN-GV--GEG-RGASEPEGEPEPRARADLE--VLQAGFERLQSLPELAERL 554
              RG+PG  G  G+  GEG +G   P G P  R  A     +   G    Q  P  A   
Sbjct: 1042 GERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEK 1101

Query: 555  GGRCPGQVA-HGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGS 613
            G   PG+    G   R G+      PG AG            ++G             G 
Sbjct: 1102 GA--PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG-----------EPGQ 1148

Query: 614  RRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSST--------------PECP 659
            + +   +      G   L     +G      G G  GPR                 P  P
Sbjct: 1149 KGSKGDKGENGPPGPPGLQG--PVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPP 1206

Query: 660  VVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGP-GPV-PGGLSVPT-PCGR-----GAG 711
               G + GL  P   E+G  G    +  PG  GP GP  P G   P  P G      G G
Sbjct: 1207 GPIGLQ-GLPGPPG-EKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVG 1264

Query: 712  DFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAAL--------RKGAPREQPPASPAASP 763
            +  E   A    P   AG + G +  RG    A           KG P +  P      P
Sbjct: 1265 EKGEPGEAGNPGPPGEAG-VGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPG-P 1322

Query: 764  CQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGL-GVPSQQGPT 822
               P  P    E P   G+      +     PG  G     P P+   G  G P ++GP 
Sbjct: 1323 VGFPGDPGPPGE-PGPAGQDGVGGDKGEDGDPGQPG----PPGPSGEAGPPGPPGKRGPP 1377

Query: 823  GSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAPA 862
            G+ G   R     A  EAG+     + G    P  P+ PA
Sbjct: 1378 GAAGAEGRQGEKGAKGEAGAEGPPGKTG----PVGPQGPA 1413



 Score = 37.0 bits (84), Expect = 0.079
 Identities = 46/150 (30%), Positives = 60/150 (40%), Gaps = 28/150 (18%)

Query: 455  GPCWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLRRG------------ 502
            GP  +A    P G+ RG PG  AGA GR+G   A+G  G      + G            
Sbjct: 1360 GPSGEAGPPGPPGK-RGPPG-AAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG 1417

Query: 503  ----RGMPGRVGNGVGEG-RGASEPEGEPEPRARADLEVLQA--GFERLQSLPELAERLG 555
                RG+PG VG    +G  GA+  +G P P     L  L+   G +  +  P L   +G
Sbjct: 1418 PEGLRGIPGPVGE---QGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIG 1474

Query: 556  GRCPGQVAHGVLARAGLLAAAARPGLAGSG 585
               PG+   G     GL      PG  G G
Sbjct: 1475 P--PGE--QGEKGDRGLPGTQGSPGAKGDG 1500



 Score = 34.7 bits (78), Expect = 0.39
 Identities = 56/213 (26%), Positives = 68/213 (31%), Gaps = 22/213 (10%)

Query: 675  ERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCG-------RGA-GDFSEADLADRAFPVR 726
            E G PG+P      G  GP   PG    P   G       +GA G+        +  PV 
Sbjct: 1349 EDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVG 1408

Query: 727  GAGPIA-----GRRRRRGWTFAAALRKGAPREQPPAS---PAASPCQAPRAPEKETEAPR 778
              GP       G R   G      L   A ++ PP     P     +     + E   P 
Sbjct: 1409 PQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPG 1468

Query: 779  LRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGA 838
            L G    + P       G  GL   Q  P      G+P   GP G PG            
Sbjct: 1469 LIG---LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKG 1525

Query: 839  EAGSMETFLRNG--GL-YPPPSPRAPAVCVQHL 868
              GS     + G  GL  PP SP  P   +Q L
Sbjct: 1526 NKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPL 1558


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 111/402 (27%), Positives = 139/402 (34%), Gaps = 39/402 (9%)

Query: 445  GETTPLGEARGPCWK-ARGAVPSGRLRGRPGRVA--GASGRRGASQARGGTGR-APARLR 500
            G   P G    P +  A G   +  + G+PG     G +G RG+  ARG TG+  P    
Sbjct: 808  GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS 867

Query: 501  RGRGMPGRVGNGVGEGR----GASEPEGEPEPRARADLEVLQAGFERLQSLPELAERLGG 556
             G G PG  G    +G     G   P+G P P  +  L     G    +       + G 
Sbjct: 868  GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLP----GHPGQRGETGFQGKTGP 923

Query: 557  RCPGQVA--HGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSR 614
              PG V    G     G +     PG  G   ++ L  AA + G        P  +  S 
Sbjct: 924  PGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKG----DPGPQGISG 979

Query: 615  RAGNHRVREIEFGSALLAALNTLGPGSFGA-GL-GAQGPRSSTPECPVVNGSEWGLAAPL 672
            + G   +R       L        PG+ GA GL G +GP+   P  PV +  E G A   
Sbjct: 980  KDGPAGLRGFPGERGL--------PGAQGAPGLKGGEGPQG--PPGPVGSPGERGSAGTA 1029

Query: 673  SPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIA 732
             P  G PGRP     PG  G    PG      P GR  G      L   A P    G   
Sbjct: 1030 GPI-GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD-GVQGPVGLPGPAGPAGSPGE-D 1086

Query: 733  GRRRRRGWTFAAALRKGAPREQPPASPAAS-PCQAPRAPEKETE-APR----LRGRATAV 786
            G +   G       +       PP  P    P  AP     + E  PR    + G+    
Sbjct: 1087 GDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDE 1146

Query: 787  APRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCR 828
              R  P  PG  GL  L   P      G     GP G PG R
Sbjct: 1147 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1188



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 100/404 (24%), Positives = 132/404 (32%), Gaps = 77/404 (19%)

Query: 473  PGRVAGASGRRGASQARGGTG-------RAPARLRRGRGMPGRVGNGVGEG----RGASE 521
            P  V GA G RG   ++G  G       +    L+  RG  G++G    +G    +G + 
Sbjct: 722  PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAG 781

Query: 522  PEGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGL 581
            P G+P P         QAG +    +P L              G   R G   +   PG 
Sbjct: 782  PTGDPGPSG-------QAGEKGKLGVPGLP-------------GYPGRQGPKGSTGFPGF 821

Query: 582  AGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGS 641
             G+  ++     A + G        P  +RG       R      G          GP  
Sbjct: 822  PGANGEKGARGVAGKPG--------PRGQRGPTGPRGSRGARGPTGKP--------GPKG 865

Query: 642  FGAGLGAQGPRSST----PECPVVNGSEWGLAAPLSPER--GSPGRPAFLRSPGLCGPGP 695
               G G  GP        P+ PV      G   P   +   G PG+       G  GP P
Sbjct: 866  TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP-P 924

Query: 696  VPGGLSVPT-------PCGRGAGDFSEADLADRAFP----VRGAGPIAGRRRRRGWTFAA 744
             PGG+  P        P G            ++  P      GA    G +   G    A
Sbjct: 925  GPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPA 984

Query: 745  ALR-----KGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSG 799
             LR     +G P  Q   +P     + P+ P     +P  RG A    P  LP  PG  G
Sbjct: 985  GLRGFPGERGLPGAQ--GAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQG 1042

Query: 800  LCVLQPFPARSRGL-GVPSQQGPTGSPGCRDRASAPRAGAEAGS 842
                 P PA  +G  G    QGP G  G +     P     AGS
Sbjct: 1043 ----PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1082



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 115/435 (26%), Positives = 148/435 (34%), Gaps = 92/435 (21%)

Query: 469 LRGRPGRVAGASGRRGASQARGGTGRAPARLRRG-RGMPGRVGNGVGEGR-GASEPEGEP 526
           L GRPG V G     G+S A+G +G    +  RG +G PG  G     GR GA    G P
Sbjct: 497 LTGRPGPVGGP----GSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMP 552

Query: 527 -EPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVA-----HGVLARAGLLAAAARPG 580
            EP A+ D      GF+ L  LP      G R P          G+    G +     PG
Sbjct: 553 GEPGAKGD-----RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPG 607

Query: 581 LAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPG 640
            AG    R L              + P   RG+  A          G   +A ++  GP 
Sbjct: 608 EAGP---RGL--------------LGP---RGTPGAP---------GQPGMAGVD--GPP 636

Query: 641 SFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP-----ERGSPGRPAFLRSPGLCGPGP 695
                +G QG     P     N    GL  P  P     E+G  G+P     PG  GP  
Sbjct: 637 GPKGNMGPQGEPG--PPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPG 694

Query: 696 VPGG------------------LSVPTPCGRGAGD------FSEADLADRAFP-VRGAGP 730
            PG                   +  P P G    D       S+ +  +  FP  +G   
Sbjct: 695 HPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG 754

Query: 731 IAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEK-ETEAPRLRGRATAVAPR 789
           + G R   G         G    +  A P   P  + +A EK +   P L G      P+
Sbjct: 755 LKGDRGEVG-QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 813

Query: 790 PLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRD-RASAPRAGAEAGSMETFLR 848
                PGF G    +     +   G   Q+GPTG  G R  R    + G +  S      
Sbjct: 814 GSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS------ 867

Query: 849 NGGLYP--PPSPRAP 861
            GG  P  PP  R P
Sbjct: 868 -GGDGPPGPPGERGP 881



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 61/208 (29%), Positives = 75/208 (36%), Gaps = 33/208 (15%)

Query: 639 PGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP-----ERGSPGRPAFLRSPGLCGP 693
           P     G+  +GP    P  P       GL  P  P     +RG PGRP    + GL  P
Sbjct: 392 PAVVEPGMLVEGPPG--PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGL--P 447

Query: 694 GPVPGGLSVPTPCGRGAGDFS------------EADLADRAFPVRG-AGP--IAGRRRRR 738
           GP    L +P    R  GD S            +A L      +RG  GP  + GR    
Sbjct: 448 GPPGTMLMLPF---RYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPV 504

Query: 739 GWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFS 798
           G   ++   KG   +  P  P     Q P  P   T  P  RGR  A   R +P  PG  
Sbjct: 505 GGPGSSG-AKGESGDPGPQGPRG--VQGPPGP---TGKPGKRGRPGADGGRGMPGEPGAK 558

Query: 799 GLCVLQPFPARSRGLGVPSQQGPTGSPG 826
           G       P      G   ++GP G PG
Sbjct: 559 GDRGFDGLPGLPGDKGHRGERGPQGPPG 586



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 100/402 (24%), Positives = 126/402 (31%), Gaps = 80/402 (19%)

Query: 469 LRGRPGRVA-----GASGRRGASQARGGTGRAPARLRRGRGMPGRVG-NGVGEGRGASEP 522
           +RG  G +      G +G RG    RG  G AP       G PG  G +G    +G   P
Sbjct: 593 MRGEDGEIGPRGLPGEAGPRGLLGPRGTPG-AP-------GQPGMAGVDGPPGPKGNMGP 644

Query: 523 EGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVA-HGVLARAGLLAAAARPGL 581
           +GEP P         Q G    Q LP     +G   PG+    G    AGL  A   PG 
Sbjct: 645 QGEPGPPG-------QQGNPGPQGLPGPQGPIGP--PGEKGPQGKPGLAGLPGADGPPGH 695

Query: 582 AGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGS 641
            G   Q           G    +  P  +      G   V+  +    L  +    G   
Sbjct: 696 PGKEGQ----------SGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDG 745

Query: 642 FGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLS 701
           F    G  G +    E   +     G      PE G  GR      PG  G     G L 
Sbjct: 746 FPGFKGDMGLKGDRGEVGQI-----GPRGEDGPE-GPKGRAGPTGDPGPSGQAGEKGKLG 799

Query: 702 VPTPCGRGAGDFSEADLADRAFP----VRGAGPIAGRRRRRGWTFAAALRKGAPREQPPA 757
           VP   G       +       FP     +GA  +AG+   RG             ++ P 
Sbjct: 800 VPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRG-------------QRGPT 846

Query: 758 SPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRG-LGVP 816
            P  S     R     T  P  +G +    P   P  PG  G       P   +G +G P
Sbjct: 847 GPRGS-----RGARGPTGKPGPKGTSGGDGP---PGPPGERG-------PQGPQGPVGFP 891

Query: 817 SQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSP 858
             +GP G PG       P    E G         G   PP P
Sbjct: 892 GPKGPPGPPGKDGLPGHPGQRGETGFQ-------GKTGPPGP 926



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 124/460 (26%), Positives = 158/460 (34%), Gaps = 76/460 (16%)

Query: 445  GETTPLGEARGPCWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTGR-APARLRR-- 501
            GET P+GE   P        P G  +G PG  AG  G +G    +G +G+  PA LR   
Sbjct: 937  GETGPIGERGHPGPPG----PPGE-QGLPG-AAGKEGAKGDPGPQGISGKDGPAGLRGFP 990

Query: 502  -GRGMPGRVGN-GV--GEG-RGASEPEGEPEPRARADLE--VLQAGFERLQSLPELAERL 554
              RG+PG  G  G+  GEG +G   P G P  R  A     +   G    Q  P  A   
Sbjct: 991  GERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEK 1050

Query: 555  GGRCPGQVA-HGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGS 613
            G   PG+    G   R G+      PG AG            ++G             G 
Sbjct: 1051 GA--PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG-----------EPGQ 1097

Query: 614  RRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSST--------------PECP 659
            + +   +      G   L     +G      G G  GPR                 P  P
Sbjct: 1098 KGSKGDKGENGPPGPPGLQG--PVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPP 1155

Query: 660  VVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGP-GPV-PGGLSVPT-PCGR-----GAG 711
               G + GL  P   E+G  G    +  PG  GP GP  P G   P  P G      G G
Sbjct: 1156 GPIGLQ-GLPGPPG-EKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVG 1213

Query: 712  DFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAAL--------RKGAPREQPPASPAASP 763
            +  E   A    P   AG + G +  RG    A           KG P +  P      P
Sbjct: 1214 EKGEPGEAGNPGPPGEAG-VGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPG-P 1271

Query: 764  CQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGL-GVPSQQGPT 822
               P  P    E P   G+      +     PG  G     P P+   G  G P ++GP 
Sbjct: 1272 VGFPGDPGPPGE-PGPAGQDGVGGDKGEDGDPGQPG----PPGPSGEAGPPGPPGKRGPP 1326

Query: 823  GSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAPA 862
            G+ G   R     A  EAG+     + G    P  P+ PA
Sbjct: 1327 GAAGAEGRQGEKGAKGEAGAEGPPGKTG----PVGPQGPA 1362



 Score = 37.0 bits (84), Expect = 0.079
 Identities = 46/150 (30%), Positives = 60/150 (40%), Gaps = 28/150 (18%)

Query: 455  GPCWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLRRG------------ 502
            GP  +A    P G+ RG PG  AGA GR+G   A+G  G      + G            
Sbjct: 1309 GPSGEAGPPGPPGK-RGPPG-AAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG 1366

Query: 503  ----RGMPGRVGNGVGEG-RGASEPEGEPEPRARADLEVLQA--GFERLQSLPELAERLG 555
                RG+PG VG    +G  GA+  +G P P     L  L+   G +  +  P L   +G
Sbjct: 1367 PEGLRGIPGPVGE---QGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIG 1423

Query: 556  GRCPGQVAHGVLARAGLLAAAARPGLAGSG 585
               PG+   G     GL      PG  G G
Sbjct: 1424 P--PGE--QGEKGDRGLPGTQGSPGAKGDG 1449



 Score = 34.7 bits (78), Expect = 0.39
 Identities = 56/213 (26%), Positives = 68/213 (31%), Gaps = 22/213 (10%)

Query: 675  ERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCG-------RGA-GDFSEADLADRAFPVR 726
            E G PG+P      G  GP   PG    P   G       +GA G+        +  PV 
Sbjct: 1298 EDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVG 1357

Query: 727  GAGPIA-----GRRRRRGWTFAAALRKGAPREQPPAS---PAASPCQAPRAPEKETEAPR 778
              GP       G R   G      L   A ++ PP     P     +     + E   P 
Sbjct: 1358 PQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPG 1417

Query: 779  LRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGA 838
            L G    + P       G  GL   Q  P      G+P   GP G PG            
Sbjct: 1418 LIG---LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKG 1474

Query: 839  EAGSMETFLRNG--GL-YPPPSPRAPAVCVQHL 868
              GS     + G  GL  PP SP  P   +Q L
Sbjct: 1475 NKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPL 1507


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 111/402 (27%), Positives = 139/402 (34%), Gaps = 39/402 (9%)

Query: 445  GETTPLGEARGPCWK-ARGAVPSGRLRGRPGRVA--GASGRRGASQARGGTGR-APARLR 500
            G   P G    P +  A G   +  + G+PG     G +G RG+  ARG TG+  P    
Sbjct: 847  GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS 906

Query: 501  RGRGMPGRVGNGVGEGR----GASEPEGEPEPRARADLEVLQAGFERLQSLPELAERLGG 556
             G G PG  G    +G     G   P+G P P  +  L     G    +       + G 
Sbjct: 907  GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLP----GHPGQRGETGFQGKTGP 962

Query: 557  RCPGQVA--HGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSR 614
              PG V    G     G +     PG  G   ++ L  AA + G        P  +  S 
Sbjct: 963  PGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKG----DPGPQGISG 1018

Query: 615  RAGNHRVREIEFGSALLAALNTLGPGSFGA-GL-GAQGPRSSTPECPVVNGSEWGLAAPL 672
            + G   +R       L        PG+ GA GL G +GP+   P  PV +  E G A   
Sbjct: 1019 KDGPAGLRGFPGERGL--------PGAQGAPGLKGGEGPQG--PPGPVGSPGERGSAGTA 1068

Query: 673  SPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIA 732
             P  G PGRP     PG  G    PG      P GR  G      L   A P    G   
Sbjct: 1069 GPI-GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD-GVQGPVGLPGPAGPAGSPGE-D 1125

Query: 733  GRRRRRGWTFAAALRKGAPREQPPASPAAS-PCQAPRAPEKETE-APR----LRGRATAV 786
            G +   G       +       PP  P    P  AP     + E  PR    + G+    
Sbjct: 1126 GDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDE 1185

Query: 787  APRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCR 828
              R  P  PG  GL  L   P      G     GP G PG R
Sbjct: 1186 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1227



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 100/404 (24%), Positives = 132/404 (32%), Gaps = 77/404 (19%)

Query: 473  PGRVAGASGRRGASQARGGTG-------RAPARLRRGRGMPGRVGNGVGEG----RGASE 521
            P  V GA G RG   ++G  G       +    L+  RG  G++G    +G    +G + 
Sbjct: 761  PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAG 820

Query: 522  PEGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGL 581
            P G+P P         QAG +    +P L              G   R G   +   PG 
Sbjct: 821  PTGDPGPSG-------QAGEKGKLGVPGLP-------------GYPGRQGPKGSTGFPGF 860

Query: 582  AGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGS 641
             G+  ++     A + G        P  +RG       R      G          GP  
Sbjct: 861  PGANGEKGARGVAGKPG--------PRGQRGPTGPRGSRGARGPTGKP--------GPKG 904

Query: 642  FGAGLGAQGPRSST----PECPVVNGSEWGLAAPLSPER--GSPGRPAFLRSPGLCGPGP 695
               G G  GP        P+ PV      G   P   +   G PG+       G  GP P
Sbjct: 905  TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP-P 963

Query: 696  VPGGLSVPT-------PCGRGAGDFSEADLADRAFP----VRGAGPIAGRRRRRGWTFAA 744
             PGG+  P        P G            ++  P      GA    G +   G    A
Sbjct: 964  GPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPA 1023

Query: 745  ALR-----KGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSG 799
             LR     +G P  Q   +P     + P+ P     +P  RG A    P  LP  PG  G
Sbjct: 1024 GLRGFPGERGLPGAQ--GAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQG 1081

Query: 800  LCVLQPFPARSRGL-GVPSQQGPTGSPGCRDRASAPRAGAEAGS 842
                 P PA  +G  G    QGP G  G +     P     AGS
Sbjct: 1082 ----PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1121



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 115/435 (26%), Positives = 148/435 (34%), Gaps = 92/435 (21%)

Query: 469 LRGRPGRVAGASGRRGASQARGGTGRAPARLRRG-RGMPGRVGNGVGEGR-GASEPEGEP 526
           L GRPG V G     G+S A+G +G    +  RG +G PG  G     GR GA    G P
Sbjct: 536 LTGRPGPVGGP----GSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMP 591

Query: 527 -EPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVA-----HGVLARAGLLAAAARPG 580
            EP A+ D      GF+ L  LP      G R P          G+    G +     PG
Sbjct: 592 GEPGAKGD-----RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPG 646

Query: 581 LAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPG 640
            AG    R L              + P   RG+  A          G   +A ++  GP 
Sbjct: 647 EAGP---RGL--------------LGP---RGTPGAP---------GQPGMAGVD--GPP 675

Query: 641 SFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP-----ERGSPGRPAFLRSPGLCGPGP 695
                +G QG     P     N    GL  P  P     E+G  G+P     PG  GP  
Sbjct: 676 GPKGNMGPQGEPG--PPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPG 733

Query: 696 VPGG------------------LSVPTPCGRGAGD------FSEADLADRAFP-VRGAGP 730
            PG                   +  P P G    D       S+ +  +  FP  +G   
Sbjct: 734 HPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG 793

Query: 731 IAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEK-ETEAPRLRGRATAVAPR 789
           + G R   G         G    +  A P   P  + +A EK +   P L G      P+
Sbjct: 794 LKGDRGEVG-QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 852

Query: 790 PLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRD-RASAPRAGAEAGSMETFLR 848
                PGF G    +     +   G   Q+GPTG  G R  R    + G +  S      
Sbjct: 853 GSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS------ 906

Query: 849 NGGLYP--PPSPRAP 861
            GG  P  PP  R P
Sbjct: 907 -GGDGPPGPPGERGP 920



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 61/208 (29%), Positives = 75/208 (36%), Gaps = 33/208 (15%)

Query: 639 PGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP-----ERGSPGRPAFLRSPGLCGP 693
           P     G+  +GP    P  P       GL  P  P     +RG PGRP    + GL  P
Sbjct: 431 PAVVEPGMLVEGPPG--PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGL--P 486

Query: 694 GPVPGGLSVPTPCGRGAGDFS------------EADLADRAFPVRG-AGP--IAGRRRRR 738
           GP    L +P    R  GD S            +A L      +RG  GP  + GR    
Sbjct: 487 GPPGTMLMLPF---RYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPV 543

Query: 739 GWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFS 798
           G   ++   KG   +  P  P     Q P  P   T  P  RGR  A   R +P  PG  
Sbjct: 544 GGPGSSG-AKGESGDPGPQGPRG--VQGPPGP---TGKPGKRGRPGADGGRGMPGEPGAK 597

Query: 799 GLCVLQPFPARSRGLGVPSQQGPTGSPG 826
           G       P      G   ++GP G PG
Sbjct: 598 GDRGFDGLPGLPGDKGHRGERGPQGPPG 625



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 100/402 (24%), Positives = 126/402 (31%), Gaps = 80/402 (19%)

Query: 469 LRGRPGRVA-----GASGRRGASQARGGTGRAPARLRRGRGMPGRVG-NGVGEGRGASEP 522
           +RG  G +      G +G RG    RG  G AP       G PG  G +G    +G   P
Sbjct: 632 MRGEDGEIGPRGLPGEAGPRGLLGPRGTPG-AP-------GQPGMAGVDGPPGPKGNMGP 683

Query: 523 EGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVA-HGVLARAGLLAAAARPGL 581
           +GEP P         Q G    Q LP     +G   PG+    G    AGL  A   PG 
Sbjct: 684 QGEPGPPG-------QQGNPGPQGLPGPQGPIGP--PGEKGPQGKPGLAGLPGADGPPGH 734

Query: 582 AGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGS 641
            G   Q           G    +  P  +      G   V+  +    L  +    G   
Sbjct: 735 PGKEGQ----------SGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDG 784

Query: 642 FGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLS 701
           F    G  G +    E   +     G      PE G  GR      PG  G     G L 
Sbjct: 785 FPGFKGDMGLKGDRGEVGQI-----GPRGEDGPE-GPKGRAGPTGDPGPSGQAGEKGKLG 838

Query: 702 VPTPCGRGAGDFSEADLADRAFP----VRGAGPIAGRRRRRGWTFAAALRKGAPREQPPA 757
           VP   G       +       FP     +GA  +AG+   RG             ++ P 
Sbjct: 839 VPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRG-------------QRGPT 885

Query: 758 SPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRG-LGVP 816
            P  S     R     T  P  +G +    P   P  PG  G       P   +G +G P
Sbjct: 886 GPRGS-----RGARGPTGKPGPKGTSGGDGP---PGPPGERG-------PQGPQGPVGFP 930

Query: 817 SQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSP 858
             +GP G PG       P    E G         G   PP P
Sbjct: 931 GPKGPPGPPGKDGLPGHPGQRGETGFQ-------GKTGPPGP 965



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 124/460 (26%), Positives = 158/460 (34%), Gaps = 76/460 (16%)

Query: 445  GETTPLGEARGPCWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTGR-APARLRR-- 501
            GET P+GE   P        P G  +G PG  AG  G +G    +G +G+  PA LR   
Sbjct: 976  GETGPIGERGHPGPPG----PPGE-QGLPG-AAGKEGAKGDPGPQGISGKDGPAGLRGFP 1029

Query: 502  -GRGMPGRVGN-GV--GEG-RGASEPEGEPEPRARADLE--VLQAGFERLQSLPELAERL 554
              RG+PG  G  G+  GEG +G   P G P  R  A     +   G    Q  P  A   
Sbjct: 1030 GERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEK 1089

Query: 555  GGRCPGQVA-HGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGS 613
            G   PG+    G   R G+      PG AG            ++G             G 
Sbjct: 1090 GA--PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG-----------EPGQ 1136

Query: 614  RRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSST--------------PECP 659
            + +   +      G   L     +G      G G  GPR                 P  P
Sbjct: 1137 KGSKGDKGENGPPGPPGLQG--PVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPP 1194

Query: 660  VVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGP-GPV-PGGLSVPT-PCGR-----GAG 711
               G + GL  P   E+G  G    +  PG  GP GP  P G   P  P G      G G
Sbjct: 1195 GPIGLQ-GLPGPPG-EKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVG 1252

Query: 712  DFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAAL--------RKGAPREQPPASPAASP 763
            +  E   A    P   AG + G +  RG    A           KG P +  P      P
Sbjct: 1253 EKGEPGEAGNPGPPGEAG-VGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPG-P 1310

Query: 764  CQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGL-GVPSQQGPT 822
               P  P    E P   G+      +     PG  G     P P+   G  G P ++GP 
Sbjct: 1311 VGFPGDPGPPGE-PGPAGQDGVGGDKGEDGDPGQPG----PPGPSGEAGPPGPPGKRGPP 1365

Query: 823  GSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAPA 862
            G+ G   R     A  EAG+     + G    P  P+ PA
Sbjct: 1366 GAAGAEGRQGEKGAKGEAGAEGPPGKTG----PVGPQGPA 1401



 Score = 37.0 bits (84), Expect = 0.079
 Identities = 46/150 (30%), Positives = 60/150 (40%), Gaps = 28/150 (18%)

Query: 455  GPCWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLRRG------------ 502
            GP  +A    P G+ RG PG  AGA GR+G   A+G  G      + G            
Sbjct: 1348 GPSGEAGPPGPPGK-RGPPG-AAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG 1405

Query: 503  ----RGMPGRVGNGVGEG-RGASEPEGEPEPRARADLEVLQA--GFERLQSLPELAERLG 555
                RG+PG VG    +G  GA+  +G P P     L  L+   G +  +  P L   +G
Sbjct: 1406 PEGLRGIPGPVGE---QGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIG 1462

Query: 556  GRCPGQVAHGVLARAGLLAAAARPGLAGSG 585
               PG+   G     GL      PG  G G
Sbjct: 1463 P--PGE--QGEKGDRGLPGTQGSPGAKGDG 1488



 Score = 34.7 bits (78), Expect = 0.39
 Identities = 56/213 (26%), Positives = 68/213 (31%), Gaps = 22/213 (10%)

Query: 675  ERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCG-------RGA-GDFSEADLADRAFPVR 726
            E G PG+P      G  GP   PG    P   G       +GA G+        +  PV 
Sbjct: 1337 EDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVG 1396

Query: 727  GAGPIA-----GRRRRRGWTFAAALRKGAPREQPPAS---PAASPCQAPRAPEKETEAPR 778
              GP       G R   G      L   A ++ PP     P     +     + E   P 
Sbjct: 1397 PQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPG 1456

Query: 779  LRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGA 838
            L G    + P       G  GL   Q  P      G+P   GP G PG            
Sbjct: 1457 LIG---LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKG 1513

Query: 839  EAGSMETFLRNG--GL-YPPPSPRAPAVCVQHL 868
              GS     + G  GL  PP SP  P   +Q L
Sbjct: 1514 NKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPL 1546


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 127/455 (27%), Positives = 147/455 (32%), Gaps = 85/455 (18%)

Query: 440  RGARAGETTPLGEARGPCWKARGAVPSGRLRGRPGRVA--------------------GA 479
            RG   G+  PLG    P  K +  VP   L G PGR                      G 
Sbjct: 848  RGGPNGDPGPLGP---PGEKGKLGVPG--LPGYPGRQGPKGSIGFPGFPGANGEKGGRGT 902

Query: 480  SGRRGASQARGGTGRAPARLRRG-RGMPGRVGNGVGEG----------RGASEPEGEPEP 528
             G+ G    RG TG    R  RG  G PG  GN  G+G           G   P G P P
Sbjct: 903  PGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGP 962

Query: 529  RARADLEVLQAGFERLQSLPELAERLG--GRC-----PGQVA-HGVLARAGLLAAAARPG 580
            +          G + L   P      G  G+      PG V   G     G +     PG
Sbjct: 963  KGPPG----PPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPG 1018

Query: 581  LAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPG 640
              G   ++ L   A + G        P       + G   +R       L        PG
Sbjct: 1019 PPGPPGEQGLPGLAGKEG----TKGDPGPAGLPGKDGPPGLRGFPGDRGL--------PG 1066

Query: 641  SFGA-GL-GAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPG 698
              GA GL G +GP    P  P  +  E G A    P  G PGRP     PG  G    PG
Sbjct: 1067 PVGALGLKGNEGPPG--PPGPAGSPGERGPAGAAGPI-GIPGRPGPQGPPGPAGEKGAPG 1123

Query: 699  GLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIA-----GRRRRRGWTFAAALRKGAPRE 753
                  P GR  G      L   A PV   G        G   ++G        KG   E
Sbjct: 1124 EKGPQGPAGRD-GLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKG-------SKGDKGE 1175

Query: 754  QPPASPAA--SPCQAPRAPEKETE-APR----LRGRATAVAPRPLPAAPGFSGLCVLQPF 806
            Q P  P     P   P     + E  PR    L G+     PR  P  PG  GL  L   
Sbjct: 1176 QGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGP 1235

Query: 807  PARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAG 841
            P      G   Q GP G PG R  + AP A    G
Sbjct: 1236 PGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQG 1270



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 107/414 (25%), Positives = 136/414 (32%), Gaps = 64/414 (15%)

Query: 445  GETTPLGEARGPCWKARGAVPSGR--LRGRPGRV--AGASGRRGASQARGGTGRAPARLR 500
            G   P GE   P  K     P+GR  L+G  G    AG  G  G    +G  G    +  
Sbjct: 1111 GPPGPAGEKGAPGEKGPQG-PAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGS 1169

Query: 501  RG----RGMPGRVGNGVGEGR-GASEPEGEPEPRARADLEVLQAGFERLQSLPELAERLG 555
            +G    +G PG  G     G+ G S  +GEP PR +  L   Q G E  +  P     +G
Sbjct: 1170 KGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGL-FGQKGDEGPRGFPGPPGPVG 1228

Query: 556  GR-CPGQVAH-GVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGS 613
             +  PG     G     G +     PG  G              GG            G+
Sbjct: 1229 LQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGI-----------GN 1277

Query: 614  RRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLS 673
              A   +    E G           PG  G G G  GP+    E      S  G A P  
Sbjct: 1278 PGAVGEKGEPGEAGE----------PGLPGEG-GPPGPKGERGEKGESGPS--GAAGPPG 1324

Query: 674  PERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGA-----GDFSEADLADRAFPVRGA 728
            P +G PG      SPG  G    PG    P P G+       GD  E        P    
Sbjct: 1325 P-KGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEP 1383

Query: 729  GPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPC-QAPRAPEKETEAPRLRGRATAVA 787
            GP                  G P ++ P  PA     Q  +  + E       G+   + 
Sbjct: 1384 GP-----------------SGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIG 1426

Query: 788  PRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAG 841
            P+  P  PG  GL  + P P   +GL  P   GP G PG       P    ++G
Sbjct: 1427 PQGAPGKPGPDGLRGI-PGPVGEQGL--PGSPGPDGPPGPMGPPGLPGLKGDSG 1477



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 97/376 (25%), Positives = 114/376 (30%), Gaps = 37/376 (9%)

Query: 502 GRGMPGR---VGNGVGEGRGASEPEGEPEPRARADLEVLQAGFERLQSLPELAERLG--G 556
           G GMP     +  G+G  RG    +GEP       L     G E    LP     +G  G
Sbjct: 431 GPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTG 490

Query: 557 RCPGQVAHGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRA 616
           +       G   R GL  A   PG  G+ +            G           +G   +
Sbjct: 491 QVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAG----------SKGPMVS 540

Query: 617 GNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPER 676
                 +     A LA     GP       G  GP    P    + G E G   P  P R
Sbjct: 541 AQESQAQAILQQARLALRGPAGPMGLTGRPGPVGP----PGSGGLKG-EPGDVGPQGP-R 594

Query: 677 GSPGRPAFLRSPGLCGPGPVPGGLSVPTPCG----RG----AGDFSEADLADRAFPVRGA 728
           G  G P     PG  G     G   +P   G    RG    AG   E        P    
Sbjct: 595 GVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPP 654

Query: 729 GPIAGRRRRRGWTFAAALRKGAPREQPPAS---PAASPCQAPRAPEKETEAPRLRGRATA 785
           GP  G    RG       R G P E  P     P   P   P  P   T      G    
Sbjct: 655 GP-PGDDGERGDDGEVGPR-GLPGEPGPRGLLGPKGPP--GPPGPPGVTGMDGQPGPKGN 710

Query: 786 VAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMET 845
           V P+  P  PG  G    Q  P     +G P ++GP G PG      A       G    
Sbjct: 711 VGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGP 770

Query: 846 FLRNGGLYPPPSPRAP 861
               GG   PP P+ P
Sbjct: 771 PGEKGG-QGPPGPQGP 785



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 104/397 (26%), Positives = 134/397 (33%), Gaps = 65/397 (16%)

Query: 471  GRPGR--VAGASGRRGASQARGGTGR-APARLRRGRGMPGRVGNGVGEGRGASEPEGEPE 527
            G PG+  + G  G+RG +  +G TG   P  +   +G  G  G  +GE RG   P G P 
Sbjct: 967  GPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGP-MGE-RGHPGPPGPPG 1024

Query: 528  PRARADLEVLQ--------AGFERLQSLPELAERLGGR-CPGQVAHGVLARAGLLAAAAR 578
             +    L   +        AG       P L    G R  PG V  G L   G       
Sbjct: 1025 EQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPV--GALGLKGNEGPPGP 1082

Query: 579  PGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTL- 637
            PG AGS  +R  A AA  +G     +      +G       +    E G    A  + L 
Sbjct: 1083 PGPAGSPGERGPAGAAGPIG-----IPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQ 1137

Query: 638  GPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGP-GPV 696
            GP       G  GP       P  +G +  +  P   ++GS G       PG  GP GP+
Sbjct: 1138 GPVGLPGPAGPVGP-------PGEDGDKGEIGEP--GQKGSKGDKGEQGPPGPTGPQGPI 1188

Query: 697  -----PGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIA-----GRRRRRGWTFAAAL 746
                  G    P P G+      + D   R FP    GP+      G    +G T     
Sbjct: 1189 GQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFP-GPPGPVGLQGLPGPPGEKGETGDVG- 1246

Query: 747  RKGAPREQPPASPAASP-CQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQP 805
            + G P    P  P+ +P    P+ P      P   G          P  PG  G     P
Sbjct: 1247 QMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGG----PP 1302

Query: 806  FPARSRG----------------LGVPSQQGPTGSPG 826
             P   RG                 G P   GP GSPG
Sbjct: 1303 GPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPG 1339



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 120/449 (26%), Positives = 149/449 (33%), Gaps = 52/449 (11%)

Query: 445  GETTPLGEARGPCWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTGR-APARLRR-- 501
            GET P+GE   P        P G  +G PG +AG  G +G     G  G+  P  LR   
Sbjct: 1006 GETGPMGERGHPGPPG----PPGE-QGLPG-LAGKEGTKGDPGPAGLPGKDGPPGLRGFP 1059

Query: 502  -GRGMPGRVG----NGVGEGRGASEPEGEPEPRARADLE--VLQAGFERLQSLPELAERL 554
              RG+PG VG     G     G   P G P  R  A     +   G    Q  P  A   
Sbjct: 1060 GDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEK 1119

Query: 555  GGRCPGQVA-HGVLARAGLLAAAARPGLAGS----------------GVQRALALAAAQL 597
            G   PG+    G   R GL      PG AG                 G + +      Q 
Sbjct: 1120 GA--PGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQG 1177

Query: 598  GGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPE 657
                T    P  + G   A        + G  L       GP  F    G  G +   P 
Sbjct: 1178 PPGPTGPQGPIGQPGPSGADGEPGPRGQQG--LFGQKGDEGPRGFPGPPGPVGLQG-LPG 1234

Query: 658  CPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGA--GDFSE 715
             P   G E G    + P  G PG      +PG  GP   PGG+  P   G     G+  E
Sbjct: 1235 PPGEKG-ETGDVGQMGPP-GPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGE 1292

Query: 716  ADLADRAFPVRGAGPIAGRRRRRGWTFAAALR--KGAPREQPPASPAASPCQAPRAPEKE 773
              L     P    G   G +   G + AA     KG P +  P   +  P   P  P   
Sbjct: 1293 PGLPGEGGPPGPKGE-RGEKGESGPSGAAGPPGPKGPPGDDGPKG-SPGPVGFPGDPGPP 1350

Query: 774  TEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRG-LGVPSQQGPTGSPGCRDRAS 832
             E P   G+      +     PG +G     P P    G  G P ++GP G  G   R  
Sbjct: 1351 GE-PGPAGQDGPPGDKGDDGEPGQTG----SPGPTGEPGPSGPPGKRGPPGPAGPEGRQG 1405

Query: 833  APRAGAEAGSMETFLRNGGLYPPPSPRAP 861
               A  EAG      + G + P  +P  P
Sbjct: 1406 EKGAKGEAGLEGPPGKTGPIGPQGAPGKP 1434



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 66/253 (26%), Positives = 83/253 (32%), Gaps = 55/253 (21%)

Query: 647  GAQGPRSST--PECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSV-- 702
            G QGP+ S   P  P  NG + G        RG+PG+P      G  GP    G   +  
Sbjct: 877  GRQGPKGSIGFPGFPGANGEKGG--------RGTPGKPGPRGQRGPTGPRGERGPRGITG 928

Query: 703  -PTPCGRGAGDFSEADLADRA---------FPVRGAGP-------IAGRRRRRGWTFAAA 745
             P P G   GD       +R          FP     P       + G   +RG T    
Sbjct: 929  KPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 988

Query: 746  LR-----------KGAPREQPPASPAASPCQAPRAPEKETEAPRLRGR-ATAVAPRP--L 791
                         +G   E  P      P   P  P  E   P L G+  T   P P  L
Sbjct: 989  KTGPPGPPGVVGPQGPTGETGPMGERGHP--GPPGPPGEQGLPGLAGKEGTKGDPGPAGL 1046

Query: 792  PAA---PGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLR 848
            P     PG  G    +  P     LG+   +GP G PG    A +P     AG+      
Sbjct: 1047 PGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPG---PAGSPGERGPAGAAGPI-- 1101

Query: 849  NGGLYPPPSPRAP 861
              G+   P P+ P
Sbjct: 1102 --GIPGRPGPQGP 1112



 Score = 38.9 bits (89), Expect = 0.021
 Identities = 109/426 (25%), Positives = 135/426 (31%), Gaps = 98/426 (23%)

Query: 441 GARA--GETTPLGEARGPCWKARGAVPSGR-LRGRPGRVAGASGRRGASQARGGTGRA-- 495
           GAR   G+T P G+ RG  +     +P  +  RG PG  +G  G  G    RG  G    
Sbjct: 616 GARGMPGQTGPKGD-RG--FDGLAGLPGEKGHRGDPGP-SGPPGPPGDDGERGDDGEVGP 671

Query: 496 --------PARLRRGRGMPGRVG-------NGVGEGRGASEPEGEPEPRARADLEVLQAG 540
                   P  L   +G PG  G       +G    +G   P+GEP P         Q G
Sbjct: 672 RGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPG-------QQG 724

Query: 541 FERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGW 600
               Q LP     +G   PG+   G L + GL      PG  G            + GG 
Sbjct: 725 NPGAQGLPGPQGAIGP--PGE--KGPLGKPGL---PGMPGADGPPGHPGKEGPPGEKGGQ 777

Query: 601 TTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLG-------PGSFG--------AG 645
                 P   +G    G    R ++    +     T G       PG  G          
Sbjct: 778 -----GPPGPQGP--IGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGE 830

Query: 646 LGAQGPRSST-PECPVVNGSEWGLAAPLSP--ERGSPGRPAFLRSPGLCGPGPVPGGLSV 702
           +G  GPR    PE P   G   G   PL P  E+G  G P     PG  GP    G    
Sbjct: 831 IGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGF 890

Query: 703 PTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAAS 762
           P   G   G              RG     G R +RG                P  P   
Sbjct: 891 PGANGEKGG--------------RGTPGKPGPRGQRG----------------PTGP--- 917

Query: 763 PCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPT 822
             +  R P   T  P  +G +    P   P   G +G      FP      G P + G  
Sbjct: 918 --RGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLP 975

Query: 823 GSPGCR 828
           G PG R
Sbjct: 976 GHPGQR 981



 Score = 37.7 bits (86), Expect = 0.047
 Identities = 118/451 (26%), Positives = 141/451 (31%), Gaps = 90/451 (19%)

Query: 445  GETTPLGEARGPCWKARGAVPSGRLRGRPGRVA--GASGRRGASQARGGTGR-APARLRR 501
            GE  P G   GP        PSG   G PG     G  G++G    RG  G   P  L+ 
Sbjct: 1174 GEQGPPGPT-GPQGPIGQPGPSGA-DGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQG 1231

Query: 502  GRGMPGRVGNGVGEGRGASEPEGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQ 561
              G PG  G     G+    P G P PR  +       G +  Q  P           G 
Sbjct: 1232 LPGPPGEKGETGDVGQMG--PPGPPGPRGPSGAP----GADGPQGPP-----------GG 1274

Query: 562  VAH-GVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHR 620
            + + G +   G    A  PGL G G                     P   RG +      
Sbjct: 1275 IGNPGAVGEKGEPGEAGEPGLPGEGGPPG-----------------PKGERGEKGESGP- 1316

Query: 621  VREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP--ERGS 678
                   S         GP       G+ GP    P  P   G E G A    P  ++G 
Sbjct: 1317 -------SGAAGPPGPKGPPGDDGPKGSPGP-VGFPGDPGPPG-EPGPAGQDGPPGDKGD 1367

Query: 679  PGRPAFLRSPGLCG-PGPV--PGGLSVPTPCGRGA--GDFSEADLADRAFPVRGAGPIAG 733
             G P    SPG  G PGP   PG    P P G     G+      A    P    GPI G
Sbjct: 1368 DGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPI-G 1426

Query: 734  RRRRRGWTFAAALR-----------KGAPREQPPASPAASP----CQAPRAPEKETEAPR 778
             +   G      LR            G+P    P  P   P     +    P+ E   P 
Sbjct: 1427 PQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPG 1486

Query: 779  L------RGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRAS 832
            L       G       R LP   G SG       P   +G+  PS  GP G PG      
Sbjct: 1487 LIGLIGPPGEQGEKGDRGLPGPQGSSG-------PKGEQGITGPS--GPIGPPGPPGLPG 1537

Query: 833  AP-RAGAEAGSMETFLRNGGLYP-PPSPRAP 861
             P   GA+  S  T  +    +P PP P  P
Sbjct: 1538 PPGPKGAKGSSGPTGPKGEAGHPGPPGPPGP 1568


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 107/405 (26%), Positives = 131/405 (32%), Gaps = 100/405 (24%)

Query: 470 RGRPGRVAGASGRRGASQARGGTGR----APARLRRGRGMPGRVGN----GVGEGRGASE 521
           RGRPG + GA+G RG   ARG  G+     P       G PG  G     G     GA  
Sbjct: 308 RGRPG-LPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPG 366

Query: 522 PEGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVAH-GVLARAGLLAAAARPG 580
             GEP P+  A       G +     P +    GG+  G++   G+    GL+ A   PG
Sbjct: 367 QRGEPGPQGHA-------GAQGPPGPPGINGSPGGK--GEMGPAGIPGAPGLMGARGPPG 417

Query: 581 LAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPG 640
            AG+                     +P LR G+                         PG
Sbjct: 418 PAGANG-------------------APGLRGGAGE-----------------------PG 435

Query: 641 SFGAGLGAQGPRSSTPEC--PVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPG 698
             GA  G  GPR    E   P V G++         + GSPG P     PG  G    PG
Sbjct: 436 KNGAK-GEPGPRGERGEAGIPGVPGAKGE-----DGKDGSPGEPGANGLPGAAGERGAPG 489

Query: 699 --GLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPP 756
             G + P       G   E      A P RGA   AG   R G      +R G P    P
Sbjct: 490 FRGPAGPNGIPGEKGPAGERGAPGPAGP-RGA---AGEPGRDGVPGGPGMR-GMPGS--P 542

Query: 757 ASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVP 816
             P +     P   + E+  P   G +    PR  P   GF         P      G P
Sbjct: 543 GGPGSDGKPGPPGSQGESGRPGPPGPS---GPRGQPGVMGF---------PGPKGNDGAP 590

Query: 817 SQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAP 861
            + G  G PG       P    E G             PP P  P
Sbjct: 591 GKNGERGGPGGPGPQGPPGKNGETGPQ----------GPPGPTGP 625



 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 121/461 (26%), Positives = 137/461 (29%), Gaps = 67/461 (14%)

Query: 441  GARAGETTPLGEARGPCWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLR 500
            G   G+T P G          G  P     G+PG   G  G  GA  A GG G A A   
Sbjct: 626  GGDKGDTGPPGPQGLQGLPGTGGPPGEN--GKPGE-PGPKGDAGAPGAPGGKGDAGAPGE 682

Query: 501  RG----RGMPGRVGN----GVGEGRGASEPEGEPEPRARADLEVLQAGFERLQSLPELAE 552
            RG     G PG  G     G   G+GA+ P G P            AG   LQ +P    
Sbjct: 683  RGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGA----------AGTPGLQGMPGERG 732

Query: 553  RLGGRCP--------GQVAHGVLARAGLLAA---------AARPGLAGSGVQRALALAAA 595
             LG   P        G  A GV  + G             A +PG  G G    L   A 
Sbjct: 733  GLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAG 792

Query: 596  QLG--------GWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLG 647
              G        G       P     +   G    R               GP       G
Sbjct: 793  PRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAG 852

Query: 648  AQGPRSSTPECPVVNGSEWGLAAPLSP-ERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPC 706
              GP+    E     GS  G  A   P  RG PG P    +PG  GP   PG    P P 
Sbjct: 853  PPGPQGVKGE----RGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPA 908

Query: 707  GRGAGDFS---EADLADRAFPVRGAGPIA-GRRRRRGWTFAAALRKGAPREQPPASPAAS 762
            G      S        D   P     P A G     G    A +        PP  P   
Sbjct: 909  GNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPR 968

Query: 763  PCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPT 822
                P+  + E+  P   G +    P   P   G  GL      P R    G     G  
Sbjct: 969  GSPGPQGVKGESGKPGANGLSGERGP---PGPQGLPGLAGTAGEPGRDGNPGSDGLPGRD 1025

Query: 823  GSPGCR-DRASAPRAGAEAGSMETFLRNGGLYPPPSPRAPA 862
            GSPG + DR      GA            G   PP P  PA
Sbjct: 1026 GSPGGKGDRGENGSPGAPGAP--------GHPGPPGPVGPA 1058



 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 113/442 (25%), Positives = 142/442 (32%), Gaps = 105/442 (23%)

Query: 440 RGARAGETTPLGEARGPCWKARGAVPSGR-LRGRPGRVAG--ASGRRGASQARGGTGR-A 495
           RGA  G   P G A  P    R  VP G  +RG PG   G  + G+ G   ++G +GR  
Sbjct: 509 RGA-PGPAGPRGAAGEP---GRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPG 564

Query: 496 PARLRRGRGMPGRVG-------------NGVGEGRGASEPEGEPEPRARADLE------- 535
           P      RG PG +G             NG   G G   P+G P        +       
Sbjct: 565 PPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTG 624

Query: 536 -------VLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAGSGVQR 588
                      G + LQ LP       G  PG+  +G     G    A  PG  G    +
Sbjct: 625 PGGDKGDTGPPGPQGLQGLPGT-----GGPPGE--NGKPGEPGPKGDAGAPGAPGG---K 674

Query: 589 ALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGA 648
             A A  + G       +P LR G+                        GP     G GA
Sbjct: 675 GDAGAPGERGP-PGLAGAPGLRGGA------------------------GPPGPEGGKGA 709

Query: 649 QGP-----RSSTPECPVVNGSEWGLAAP-LSPERGSPGRPAFLRSPGLCGPGPVPGGLSV 702
            GP      + TP    + G   GL +P    ++G PG P     PG  GP    G +  
Sbjct: 710 AGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGP 769

Query: 703 PTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAAL--------------RK 748
           P P G+  GD  E   A     + G     G R   G    A                 +
Sbjct: 770 PGPAGQ-PGDKGEGG-APGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGER 827

Query: 749 GAPREQ----PPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQ 804
           GAP E+    PP          P  P          G       R  P  PG +G    +
Sbjct: 828 GAPGEKGEGGPPGVAGPPGGSGPAGPP---------GPQGVKGERGSPGGPGAAGFPGAR 878

Query: 805 PFPARSRGLGVPSQQGPTGSPG 826
             P      G P   GP+GSPG
Sbjct: 879 GLPGPPGSNGNPGPPGPSGSPG 900



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 116/412 (28%), Positives = 140/412 (33%), Gaps = 63/412 (15%)

Query: 445 GETTPLGEARGPCWKARGAVPSGRLRGRPGRV-----AGASGRRGASQARGGTGRAPARL 499
           GE  P G A      A+G      + G PG       AG  G  G   ARG  G A A  
Sbjct: 369 GEPGPQGHAG-----AQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGAN- 422

Query: 500 RRGRGMPGRVGNGVGEGRGASEPEGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCP 559
               G PG  G G GE  G +  +GEP PR        +AG   +        + G   P
Sbjct: 423 ----GAPGLRG-GAGEP-GKNGAKGEPGPRGERG----EAGIPGVPGAKGEDGKDGS--P 470

Query: 560 GQV-AHGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGN 618
           G+  A+G+   AG   A    G AG          A + G       +P    G R A  
Sbjct: 471 GEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERG-------APG-PAGPRGAAG 522

Query: 619 HRVREIEFGSALLAAL--NTLGPGSFG--AGLGAQG----PRSSTPECPVVNGSEWGLAA 670
              R+   G   +  +  +  GPGS G     G+QG    P    P  P       G   
Sbjct: 523 EPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPG 582

Query: 671 PLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGP 730
           P   + G+PG+      PG  GP   PG      P G         D  D   P    GP
Sbjct: 583 PKGND-GAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPP----GP 637

Query: 731 IAGRRRRRGWTFAAALRKGAPREQPPASPAASP----------CQAPRAPEKETEAPRLR 780
             G +   G T       G P E  P   A +P              R P     AP LR
Sbjct: 638 -QGLQGLPG-TGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLR 695

Query: 781 GRATAVAPRP------LPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPG 826
           G A    P         P  PG +G   LQ  P    GLG P  +G  G PG
Sbjct: 696 GGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPG 747



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 112/424 (26%), Positives = 138/424 (32%), Gaps = 98/424 (23%)

Query: 432 GIEAAVLLRGARA--GETTPLGEARGPCWKARGAVPSGRLRGRPGRVA--GASGRR---- 483
           GI     ++G R   G     GE   P  K    +P     G PG +   GA G R    
Sbjct: 255 GIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGEN--GAPGPMGPRGAPGERGRPG 312

Query: 484 --GASQARGGTGRAPARLRRG-------RGMPGRVG-------NGVGEGRGASEPEGEPE 527
             GA+ ARG  G   +  + G        G PG  G        G     GA    GEP 
Sbjct: 313 LPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPG 372

Query: 528 PRARADLEVLQAGFERLQSLPELAERLGGRCPGQVA-HGVLARAGLLAAAARPGLAGSGV 586
           P+         AG +     P +    GG+  G++   G+    GL+ A   PG AG+  
Sbjct: 373 PQG-------HAGAQGPPGPPGINGSPGGK--GEMGPAGIPGAPGLMGARGPPGPAGAN- 422

Query: 587 QRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGL 646
                              +P LR G+                         PG  GA  
Sbjct: 423 ------------------GAPGLRGGAGE-----------------------PGKNGA-K 440

Query: 647 GAQGPRSSTPEC--PVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPG--GLSV 702
           G  GPR    E   P V G     A     + GSPG P     PG  G    PG  G + 
Sbjct: 441 GEPGPRGERGEAGIPGVPG-----AKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAG 495

Query: 703 PTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAAS 762
           P       G   E      A P RGA   AG   R G      +R G P    P  P + 
Sbjct: 496 PNGIPGEKGPAGERGAPGPAGP-RGA---AGEPGRDGVPGGPGMR-GMPGS--PGGPGSD 548

Query: 763 PCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPT 822
               P   + E+  P   G      PR  P   GF G       P ++   G P   GP 
Sbjct: 549 GKPGPPGSQGESGRP---GPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQ 605

Query: 823 GSPG 826
           G PG
Sbjct: 606 GPPG 609



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 121/452 (26%), Positives = 144/452 (31%), Gaps = 89/452 (19%)

Query: 426 AVGLAGGIEAAVLLRGARAGETTPLGEARGPCW--KARGAVPSGRLRGRPGRVAGASGRR 483
           A GL GG  A    +    GE  P GE RG        GA       G PG   GA+G  
Sbjct: 424 APGLRGG--AGEPGKNGAKGEPGPRGE-RGEAGIPGVPGAKGEDGKDGSPGE-PGANGLP 479

Query: 484 GASQARGGTG-RAPARLRRGRGMPGRVGNGVGEGRGASEPEGEPEPRARADLEVLQAGFE 542
           GA+  RG  G R PA      G+PG  G   GE RGA  P G   PR  A     + G +
Sbjct: 480 GAAGERGAPGFRGPAG---PNGIPGEKGPA-GE-RGAPGPAG---PRGAAG----EPGRD 527

Query: 543 RLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTT 602
            +   P +   + G   G  + G     G    + RPG  G    R          G   
Sbjct: 528 GVPGGPGM-RGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPR----------GQPG 576

Query: 603 CVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVN 662
            +  P  +      G +  R               GPG    G G QGP       P  N
Sbjct: 577 VMGFPGPKGNDGAPGKNGERG--------------GPG----GPGPQGP-------PGKN 611

Query: 663 GSEWGLAAPLSP--------ERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFS 714
           G E G   P  P        + G PG       PG  GP    G    P P G      +
Sbjct: 612 G-ETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGA 670

Query: 715 EADLADRAFP-VRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQA------- 766
                D   P  RG   +AG    RG         G     PP  P A+           
Sbjct: 671 PGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGE 730

Query: 767 --------PRAPEKETEAPRLRGRATAVAPR--------PLPAA-PGFSGLCVLQPFPAR 809
                   P+  + E   P   G      PR        P PA  PG  G       P  
Sbjct: 731 RGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGI 790

Query: 810 SRGLGVPSQQGPTGSPGCRDRASAPRAGAEAG 841
           +   G P ++G TG PG      AP    E G
Sbjct: 791 AGPRGSPGERGETGPPGPAGFPGAPGQNGEPG 822



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 127/454 (27%), Positives = 157/454 (34%), Gaps = 72/454 (15%)

Query: 428  GLAGGIEAAVLLRGA--RAGETTPLGEARGPCWKARGAVPSGR-LRGRPGRVAGASGRRG 484
            G A G+      RG+    GET P G A  P    +   P G+  RG PG   G  G  G
Sbjct: 782  GGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGE-KGEGGPPG 840

Query: 485  ASQARGGTGRA----PARLRRGRGMPGRVGN-GVGEGRGASEP---EGEPEPRARADLEV 536
             +   GG+G A    P  ++  RG PG  G  G    RG   P    G P P        
Sbjct: 841  VAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPG------ 894

Query: 537  LQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAGSGVQRALALAAAQ 596
              +G       P  A   G   PG  + GV   +G    A +PG  GS   +    A   
Sbjct: 895  -PSGSPGKDGPPGPAGNTGA--PG--SPGV---SGPKGDAGQPGEKGSPGAQGPPGAPGP 946

Query: 597  LG--GWTTC--VVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLG----PGSFG----A 644
            LG  G T    +  P    G R  G+   + ++  S    A    G    PG  G    A
Sbjct: 947  LGIAGITGARGLAGPPGMPGPR--GSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLA 1004

Query: 645  GLGAQGPRSSTPEC---PVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLS 701
            G   +  R   P     P  +GS  G       E GSPG P     PG   PGPV     
Sbjct: 1005 GTAGEPGRDGNPGSDGLPGRDGSPGGKGD--RGENGSPGAPGAPGHPG--PPGPVG---- 1056

Query: 702  VPTPCGRGA--GDFSEADLADRAFPV--RGAGPIAGRRRRRGWTFAAALRKGAPREQPPA 757
               P G+    G+   A  A    P   RGA    G R  +G T              P 
Sbjct: 1057 ---PAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPG 1113

Query: 758  SPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLC--VLQPFPARSRGL-- 813
            +P A     P   +    +P   G    V P   P   G SG    +  P P  +RG   
Sbjct: 1114 NPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERG 1173

Query: 814  --------GVPSQQGPTGSPG--CRDRASAPRAG 837
                    G P   GP G+PG  C    +A  AG
Sbjct: 1174 SEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAG 1207



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 105/389 (26%), Positives = 125/389 (32%), Gaps = 85/389 (21%)

Query: 471 GRPGRVAGASGRRGASQARGGTGRAPARLRRGRGMPGRVGN-GVGEGRGASEPEGEPEPR 529
           G PG+ AG SG  G   A G +G  PA      G PGR G  G+    G   P G P   
Sbjct: 204 GEPGQ-AGPSGPPGPPGAIGPSG--PAGKDGESGRPGRPGERGLPGPPGIKGPAGIP--- 257

Query: 530 ARADLEVLQAGFERLQSLPELAERLGGRCPGQVAH-GVLARAGLLAAAARPGLAGSGVQR 588
                     GF                 PG   H G   R G       PGL G     
Sbjct: 258 ----------GF-----------------PGMKGHRGFDGRNGEKGETGAPGLKGENGLP 290

Query: 589 ALALAAAQLG--GWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLG-PGSFGAG 645
               A   +G  G       P L   +   GN   R  +          T G PGS GA 
Sbjct: 291 GENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAK 350

Query: 646 LGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTP 705
            G  GP  S    P  NG+          +RG PG      + G  GP  + G     +P
Sbjct: 351 -GEVGPAGS----PGSNGAPG--------QRGEPGPQGHAGAQGPPGPPGING-----SP 392

Query: 706 CGRGAGDFSEADLADRAFPVRGAGPIAGRRRR---RGWTFAAALRKGAPREQPPASPAAS 762
            G+G       ++     P  GA  + G R      G   A  LR GA     P    A 
Sbjct: 393 GGKG-------EMGPAGIP--GAPGLMGARGPPGPAGANGAPGLRGGAGE---PGKNGAK 440

Query: 763 PCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGL--------- 813
               PR    E   P + G          P  PG +GL    P  A  RG          
Sbjct: 441 GEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGL----PGAAGERGAPGFRGPAGP 496

Query: 814 -GVPSQQGPTGSPGCRDRASAPRAGAEAG 841
            G+P ++GP G  G    A    A  E G
Sbjct: 497 NGIPGEKGPAGERGAPGPAGPRGAAGEPG 525



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 68/242 (28%), Positives = 79/242 (32%), Gaps = 69/242 (28%)

Query: 639 PGSFGAGLGAQGPRSSTPEC-PVVNGSEWGLAAPLSP-----ERGSPGRPA---FLRSPG 689
           PGS G+  G QGP     +  P       G   P  P     E G PGRP        PG
Sbjct: 191 PGSPGSP-GYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPG 249

Query: 690 LCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFP-VRGAGPIAGRRRRRGWTFAAALR- 747
           + GP  +PG                        FP ++G     GR   +G T A  L+ 
Sbjct: 250 IKGPAGIPG------------------------FPGMKGHRGFDGRNGEKGETGAPGLKG 285

Query: 748 -KGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVA----------PRPLPAAPG 796
             G P E     P       PR    E   P L G A A            P P P  PG
Sbjct: 286 ENGLPGENGAPGP-----MGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGP-PGPPG 339

Query: 797 FSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPP 856
            +G      FP      G   + GP GSPG      AP    E G       + G   PP
Sbjct: 340 TAG------FPGSP---GAKGEVGPAGSPGSN---GAPGQRGEPGPQ----GHAGAQGPP 383

Query: 857 SP 858
            P
Sbjct: 384 GP 385



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 52/193 (26%), Positives = 66/193 (34%), Gaps = 31/193 (16%)

Query: 677 GSPGRPAFLRSPGLCGPGPVPGGLSVP---TPCGRGAGDFS-EADLADRAFPVRGAGPIA 732
           G PG P     PG+ G    PG    P     C  G  ++S + D  D    V   G +A
Sbjct: 112 GPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGV-AVGGLA 170

Query: 733 GRRRRRG--------WTFAAALRKGAPREQ-PPASPAASPCQAPRAPE----------KE 773
           G     G         T       G+P  Q PP  P  +    P  P           K+
Sbjct: 171 GYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKD 230

Query: 774 TEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARS--RGL-GVPSQQGPTGSPGCRDR 830
            E+    GR      R LP  PG  G   +  FP     RG  G   ++G TG+PG +  
Sbjct: 231 GES----GRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGE 286

Query: 831 ASAPRAGAEAGSM 843
              P      G M
Sbjct: 287 NGLPGENGAPGPM 299



 Score = 33.5 bits (75), Expect = 0.88
 Identities = 30/118 (25%), Positives = 46/118 (38%), Gaps = 21/118 (17%)

Query: 751 PREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARS 810
           P  + P     + C  P+ P   T  P  +G      P+  P  PG          P R+
Sbjct: 75  PNPEIPFGECCAVC--PQPPTAPTRPPNGQGPQ---GPKGDPGPPGI---------PGRN 120

Query: 811 RGLGVPSQQGPTGSPG----CRDRASAPRAGA---EAGSMETFLRNGGLYPPPSPRAP 861
              G+P Q G  GSPG    C    + P+  +   ++  +++ +  GGL   P P  P
Sbjct: 121 GDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGP 178


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 117/436 (26%), Positives = 143/436 (32%), Gaps = 71/436 (16%)

Query: 478 GASGRRGASQARGGTGRAPARLRRGR-------GMPGRVGNGVGEGRGASEPEGEPEPRA 530
           G  G +G+    G  GR  ++  RG        G+PG VG      RG   P G P P  
Sbjct: 527 GEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGM-----RGPQGPPGLPGPPG 581

Query: 531 RADLEVLQA--------------GFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAA 576
           R     LQ               G +     P    + G   P  VA G     G +  A
Sbjct: 582 RVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVA-GPQGEKGDVGPA 640

Query: 577 ARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFG-SALLAALN 635
             PG+ GS VQ+          G      +P    G+R       R+   G   L     
Sbjct: 641 GPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPG-PPGARGPIGPEGRDGPPGLQGLRGKKG 699

Query: 636 TLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPER----GSPGRPAFLRSPGLC 691
            +GP      LG QGP    P  P V G      +P  P      G PG P     PG  
Sbjct: 700 DMGPPGIPGLLGLQGP----PGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKD 755

Query: 692 GPGPVPGGLSVP-TPCGRGA----------GDFSEADLADRAFPVRGAG--------PIA 732
           GP   PG       P  RG           G+  E  LA R      AG         + 
Sbjct: 756 GPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVR 815

Query: 733 GRRRRRGWTFAAALR--KGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRP 790
           G +  +G      L   KG   E+  A PA  P   P      T  PR+ G       + 
Sbjct: 816 GEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPP-GLPGTTSLFTPHPRMPGEQGPKGEKG 874

Query: 791 LPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRA---SAPRAGAEAGSMETFL 847
            P  PG  GL        R   LG    QGPTG PG + +     AP A    G+     
Sbjct: 875 DPGLPGEPGL------QGRPGELG---PQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVG 925

Query: 848 RNGGLYPPPSPRAPAV 863
             G   PP S  AP +
Sbjct: 926 APGPSGPPGSVGAPGL 941



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 113/468 (24%), Positives = 143/468 (30%), Gaps = 105/468 (22%)

Query: 445  GETTPLGEARGPCWKARGAVPSGRLRGRPGRVA--------GASGRRGASQARGGTGRAP 496
            GE  P GE   P     G      L+GRPG +         GA G+ GA  A G  G   
Sbjct: 865  GEQGPKGEKGDP-----GLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPG 919

Query: 497  ARLRRGR----GMPGRVG----------NGVGEGRGASEPEGEPEPRARADLEVLQAGFE 542
            A    G     G PG VG          +G    +GA+  EG P P           G  
Sbjct: 920  APGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGP----------VGPR 969

Query: 543  RLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTT 602
                 P L        PG    G     GL  +   PG  G+        A  ++ G   
Sbjct: 970  GDPGAPGL--------PGPPGKGKDGEPGLRGSPGLPGPLGTKA------ACGKVRGSEN 1015

Query: 603  CVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVN 662
            C +     +G R A          G   +      GP       G+ G R   P  P   
Sbjct: 1016 CALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRG-LPGFPGPQ 1074

Query: 663  GSEWGLAAPLSP-ERGSPGRPAF--LRSPGL-----------CGPGP--------VPGGL 700
            G      AP +P ERG PG+P    L SPG            C PGP          G  
Sbjct: 1075 GPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDK 1134

Query: 701  SVPTPCGRGAGDFSEADLADRAFP-------------VRGAGPIAGRRRRRGWTFAAALR 747
             VP   GR   +  + +      P              RGA    G++  +G        
Sbjct: 1135 GVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFM 1194

Query: 748  KGAPREQPPASP----AASPC--------QAPRAPEKETEAPRLRGRATAVAPRPLPAAP 795
                   PP +     AA P         + P  P+  +  P + G          P  P
Sbjct: 1195 GPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPP 1254

Query: 796  GFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSM 843
            G  G       P      G P  +G TG  G      AP    E+G+M
Sbjct: 1255 GEPGKAGEPGLPGPEGARGPPGFKGHTGDSG------APGPRGESGAM 1296



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 108/417 (25%), Positives = 138/417 (33%), Gaps = 69/417 (16%)

Query: 456  PCWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTG----RAPARLRRGRGMPGRVGN 511
            P +K    VP     G+PGR  G  G++G +   G  G      P   +  RG  G VG 
Sbjct: 1128 PGFKGDKGVP-----GKPGR-EGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQ 1181

Query: 512  GVGEGR----GASEPEGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVL 567
               +G     G   P G P P   AD     AG   +Q  P      G + P  +  G+ 
Sbjct: 1182 KGDQGHPGVPGFMGPPGNPGPPG-ADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLP-GIP 1239

Query: 568  ARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFG 627
               G      +PG  G   +         L G       P  +  +  +G    R  E G
Sbjct: 1240 GEEGKEGRDGKPGPPGEPGKAG----EPGLPGPEGARGPPGFKGHTGDSGAPGPRG-ESG 1294

Query: 628  SALLAALNTLGPGSFG-----AGLGAQGPRSSTPECPVVNGSEWGLAAP----------L 672
            +  L     L PG  G        G QGPR      P  NGS      P           
Sbjct: 1295 AMGLPGQEGL-PGKDGDTGPTGPQGPQGPRGP----PGKNGSPGSPGEPGPSGTPGQKGS 1349

Query: 673  SPERGSPGRPAFLRS---PGLCGPGPVPGGLSVPTPCGRGA--GDFSEADLADRAFPVRG 727
              E GSPG P FL     PG  G   VPG   VP   G     G+  +  +     P  G
Sbjct: 1350 KGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGG 1409

Query: 728  AGP-----IAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRL--- 779
             G      I G +   G        +G P E  P  P   P Q P  P    E+P +   
Sbjct: 1410 KGQPGDPGIPGHKGHTGLMGP----QGLPGENGPVGPPGPPGQ-PGFPGLRGESPSMETL 1464

Query: 780  ---------RGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGL-GVPSQQGPTGSPG 826
                     +   T +A       P +      +P P    G  G+P + GP G PG
Sbjct: 1465 RRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPG 1521



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 123/504 (24%), Positives = 162/504 (32%), Gaps = 116/504 (23%)

Query: 428  GLAGGIEAAVLLRGARAGETTPLGEARGPCWKARGAVP----SGRLRGRPG-RVAGASGR 482
            GL G +         R  E   LG   G C K     P    S   RG PG  VAG  G 
Sbjct: 996  GLPGPLGTKAACGKVRGSENCALG---GQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGP 1052

Query: 483  RGASQARGGTGRAPARLRRGRGMPGRVGNGVGEGR-GASEPEGEPEPRARADLEVLQAGF 541
             G    +G  G         RG+PG  G     GR GA    GE  P  +  L  L +  
Sbjct: 1053 SGPPGDKGSPG--------SRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPG 1104

Query: 542  ERLQSLPELAERLGGRCPGQVAH--GVLARAGLLAAAARPGLAGSGVQRALALAAAQLGG 599
            +    +  LA+ +   CP       G+    G      +PG  G+  ++  A      G 
Sbjct: 1105 D----INLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPG- 1159

Query: 600  WTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAAL-----NTLGPGSFG-AGL------- 646
                +  P   +G R A     ++ + G   +        N   PG+ G AG        
Sbjct: 1160 -PPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQ 1218

Query: 647  ---------GAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGP---- 693
                     G QGP S  P  P   G E     P     G PG P     PGL GP    
Sbjct: 1219 GSPGKEGPPGPQGP-SGLPGIPGEEGKEGRDGKP-----GPPGEPGKAGEPGLPGPEGAR 1272

Query: 694  GPV-----PGGLSVPTPCGRGA--GDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAAL 746
            GP       G    P P G     G   +  L  +       GP  G +  RG       
Sbjct: 1273 GPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGP-QGPQGPRG----PPG 1327

Query: 747  RKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPF 806
            + G+P       P+ +P Q  +  + E  +P L G    + PR  P  PG  G+   +  
Sbjct: 1328 KNGSPGSPGEPGPSGTPGQ--KGSKGENGSPGLPG---FLGPRGPPGEPGEKGVPGKEGV 1382

Query: 807  PAR--------SRG----------------------------------LGVPSQQGPTGS 824
            P +         RG                                   G+P + GP G 
Sbjct: 1383 PGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGP 1442

Query: 825  PGCRDRASAPRAGAEAGSMETFLR 848
            PG   +   P    E+ SMET  R
Sbjct: 1443 PGPPGQPGFPGLRGESPSMETLRR 1466



 Score = 30.4 bits (67), Expect = 7.4
 Identities = 44/174 (25%), Positives = 59/174 (33%), Gaps = 27/174 (15%)

Query: 658 CPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGR----GAGDF 713
           CP     E G+A P+    G PG    +   G  GP   PG      P G     G G F
Sbjct: 478 CPAGEKGEMGVAGPM----GLPGPKGDI---GAIGPVGAPG------PKGEKGDVGIGPF 524

Query: 714 SEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQ-PPASPAASPCQAPRAPEK 772
            + +  ++   +   GP  GR   +G        +G P E   P  P     + P+ P  
Sbjct: 525 GQGEKGEKG-SLGLPGP-PGRDGSKGM-------RGEPGELGEPGLPGEVGMRGPQGPPG 575

Query: 773 ETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPG 826
               P   G       R      G  G   L  FP +    G   + GP+G  G
Sbjct: 576 LPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAG 629


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 104/396 (26%), Positives = 128/396 (32%), Gaps = 62/396 (15%)

Query: 469 LRGRPGRVA--GASGRRGASQARGGTGRAPARLRRGRGMPGRVGN-GVGEGRGASEPEGE 525
           L GRPG V   G  G +G   A G  G  P  L+   G PGRVG  G     GA    G+
Sbjct: 486 LTGRPGPVGLPGHPGLKGEEGAEGPQG--PRGLQGPHGPPGRVGKMGRPGADGARGLPGD 543

Query: 526 PEPRARADLEVLQAGFERLQSLP-------------------ELAERLGGRCPGQVAH-G 565
             P+          GF+ L  LP                   E  ER     PG     G
Sbjct: 544 TGPKG-------DRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAG 596

Query: 566 VLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIE 625
                GLL     PG  G      +  A    G     V  P       + GNH      
Sbjct: 597 EPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGN----VGPPGEPGPPGQQGNH------ 646

Query: 626 FGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFL 685
            GS  L      GP       G +GP  + P  P + GS+  L  P     G  G     
Sbjct: 647 -GSQGLP-----GPQGLIGTPGEKGPPGN-PGIPGLPGSDGPLGHP--GHEGPTGEKGAQ 697

Query: 686 RSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAA 745
             PG  GP   PG   V    G       + +  +  FP  G     G +  +G      
Sbjct: 698 GPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFP--GFKGDVGLKGDQG------ 749

Query: 746 LRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQP 805
            + GAP  +    P     QA +A E+    P   G    +    LP  PG  G      
Sbjct: 750 -KPGAPGPRGEDGPEGPKGQAGQAGEEGP--PGSAGEKGKLGVPGLPGYPGRPGPKGSIG 806

Query: 806 FPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAG 841
           FP     +G   + G TG PG       P +  E G
Sbjct: 807 FPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERG 842



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 96/399 (24%), Positives = 124/399 (31%), Gaps = 71/399 (17%)

Query: 470  RGRPGRVAGASGRRGASQARGGTGR-APARLRRGRGMPGRVGNGVGEGRGASEPEGEPEP 528
            +G+ GR  G  G+RG    +G TG   PA +   +G  G VG  +GE RG   P G P  
Sbjct: 889  QGKDGR-PGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGP-LGE-RGPPGPPGPPGE 945

Query: 529  RARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAGSGVQR 588
                            Q LP L  R G       A G L   G L      GL G     
Sbjct: 946  ----------------QGLPGLEGREG-------AKGELGPPGPLGKEGPAGLRGF---- 978

Query: 589  ALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGA 648
                              P  + G    G          + L       GP       G 
Sbjct: 979  ------------------PGPKGGPGDPGP---------TGLKGDKGPPGPVGANGSPGE 1011

Query: 649  QGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGR 708
            +GP    P   +    + G   P+ P  G  G       PG  G   +PG L    P G 
Sbjct: 1012 RGPLG--PAGGIGLPGQSGSEGPVGPA-GKKGSRGERGPPGPTGKDGIPGPLGPLGPPGA 1068

Query: 709  GAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPR 768
                  E D  D   P  G     G +   G      +R  A    PP +  A   + P 
Sbjct: 1069 AGPSGEEGDKGDVGAP--GHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPP 1126

Query: 769  APEKETEAPRLRGRATAVAP---RPLPAAPGFSGLCVLQPFPARSRGL-GVPSQQGPTGS 824
                +     +RG    + P   + LP  PG  G    +     S G  G P  +GP G 
Sbjct: 1127 GLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKG----EVGDVGSMGPHGAPGPRGPQGP 1182

Query: 825  PGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAPAV 863
             G       P    + G++      G    P  P AP +
Sbjct: 1183 TGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGI 1221



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 111/454 (24%), Positives = 149/454 (32%), Gaps = 82/454 (18%)

Query: 435  AAVLLRGARAGETTPLGEARGPCWKARGAVPSGR--LRGRPGRVA-----------GASG 481
            A VL    + GE  PLGE RGP          G   L GR G              G +G
Sbjct: 916  AGVLGPQGKTGEVGPLGE-RGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAG 974

Query: 482  RRGASQARGGTGR-APARLRRGRGMPGRVG--------------NGVG-EGRGASEPEGE 525
             RG    +GG G   P  L+  +G PG VG               G+G  G+  SE    
Sbjct: 975  LRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVG 1034

Query: 526  PEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAGSG 585
            P  +  +  E    G      +P     LG   PG  A G     G       PG  GS 
Sbjct: 1035 PAGKKGSRGERGPPGPTGKDGIPGPLGPLGP--PG--AAGPSGEEGDKGDVGAPGHKGSK 1090

Query: 586  VQRALALAAAQLG--GWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFG 643
              +  A    Q G  G       P       R G   +   +    +   +  +GP    
Sbjct: 1091 GDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQ 1150

Query: 644  AGLGAQGPRSSTPECPVVNGSEWGLAAPLSPE-----RGSPGRPAFLRSPGLCG------ 692
               G  G +    +  V +    G   P  P+      G+PG P  +  PG  G      
Sbjct: 1151 GLPGPPGEKGEVGD--VGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERG 1208

Query: 693  ----PGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRK 748
                PGP PG   +P P G   G+  ++  +  A P    GP  G    +G    +    
Sbjct: 1209 DAGDPGP-PGAPGIPGPKG-DIGEKGDSGPSGAAGPPGKKGP-PGEDGAKG----SVGPT 1261

Query: 749  GAPREQ-PPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFP 807
            G P +  PP  P  S      +P ++ +   + G          P  PG SG        
Sbjct: 1262 GLPGDLGPPGDPGVSGIDG--SPGEKGDPGDVGG----------PGPPGASG-------- 1301

Query: 808  ARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAG 841
                  G P ++GP+G  G   R     A  E G
Sbjct: 1302 -EPGAPGPPGKRGPSGHMGREGREGEKGAKGEPG 1334



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 110/423 (26%), Positives = 141/423 (33%), Gaps = 65/423 (15%)

Query: 427  VGLAGGIEAAVLLRGARAGETTPLGEAR-----------GPCWKARGAVPSGRLRGRPGR 475
            +G AGGI         ++G   P+G A            GP  K     P G L G PG 
Sbjct: 1015 LGPAGGIGLP-----GQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPL-GPPG- 1067

Query: 476  VAGASGRRGASQARGGTGRAPARLRRG-RGMPGRVGNGVGEGRGASEPEGEPEPRARADL 534
             AG SG  G     G  G   ++  +G  G PG+ G      RG   P G P P   AD 
Sbjct: 1068 AAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGI-----RG---PAGHPGPPG-AD- 1117

Query: 535  EVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAGSGVQRALALAA 594
                 G +  +  P L  + G         GV    G++      GL G   ++      
Sbjct: 1118 -----GAQGRRGPPGLFGQKGD-------DGVRGFVGVIGPPGLQGLPGPPGEKGEVGDV 1165

Query: 595  AQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLG-------PGSFGAGLG 647
              +G       +P  R      G+     +  G     A+   G       PG  GA  G
Sbjct: 1166 GSMGPHG----APGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAP-G 1220

Query: 648  AQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCG 707
              GP+    E      S  G A P   ++G PG      + G  GP  +PG L  P   G
Sbjct: 1221 IPGPKGDIGEKGDSGPS--GAAGPPG-KKGPPGEDG---AKGSVGPTGLPGDLGPPGDPG 1274

Query: 708  RGAGDFSEADLADRAFPVRGAGP--IAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQ 765
                D S  +  D    V G GP   +G     G            RE       A    
Sbjct: 1275 VSGIDGSPGEKGDPG-DVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEP 1333

Query: 766  APRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSP 825
             P  P   T     RG    V P  L   PG  G   L   P +   +G P   GP+G P
Sbjct: 1334 GPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQ---MGPPGPLGPSGLP 1390

Query: 826  GCR 828
            G +
Sbjct: 1391 GLK 1393



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 59/212 (27%), Positives = 71/212 (33%), Gaps = 45/212 (21%)

Query: 639 PGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPE-----RGSPGRPAFLRSPGLCGP 693
           PG  G   G  GP    P  P + G E G   P  P       G PGR   +  PG  G 
Sbjct: 481 PGPVGL-TGRPGP-VGLPGHPGLKGEE-GAEGPQGPRGLQGPHGPPGRVGKMGRPGADGA 537

Query: 694 GPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPRE 753
             +PG      P G            DR F   G   + G + +RG  F    + G P E
Sbjct: 538 RGLPGDTG---PKG------------DRGFD--GLPGLPGEKGQRG-DFGHVGQPGPPGE 579

Query: 754 Q-------PPA------SPAASPCQAPRAPEKETEAPRLRGRATA------VAPRPLPAA 794
                   PP        P       PR     T  P + G   A      V P   P  
Sbjct: 580 DGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGP 639

Query: 795 PGFSGLCVLQPFPARSRGLGVPSQQGPTGSPG 826
           PG  G    Q  P     +G P ++GP G+PG
Sbjct: 640 PGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPG 671



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 95/400 (23%), Positives = 119/400 (29%), Gaps = 73/400 (18%)

Query: 471  GRPGRVAGASGRRGASQARGGTGRAPARLRRGRGMPGRVGN-GVGEGRGASEPEGEPEPR 529
            G PG   G +G +GA    G  G  P      RG+ G  GN G+   +G    +G P  +
Sbjct: 683  GHPGH-EGPTGEKGAQGPPGSAG--PPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFK 739

Query: 530  ARADLEVLQ----AGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAGSG 585
                L+  Q    A   R +  PE  +   G+   +   G     G L     PG  G  
Sbjct: 740  GDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRP 799

Query: 586  VQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFG-- 643
              +        LG        P   +G          E E G           PGS G  
Sbjct: 800  GPKGSIGFPGPLG--------PIGEKGKSGKTGQPGLEGERGP----------PGSRGER 841

Query: 644  ---AGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGL 700
                  G  GP+    +                   G+PG P     PGL GP   PG  
Sbjct: 842  GQPGATGQPGPKGDVGQ------------------DGAPGIPGEKGLPGLQGPPGFPGPK 883

Query: 701  SVPTPCGRGA-----GDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQP 755
              P   G+       G   E     +  P   AG +  +              G   E  
Sbjct: 884  GPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQ--------------GKTGEVG 929

Query: 756  PASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGV 815
            P      P   P  P  E   P L GR  A      P   G  G   L+ FP    G G 
Sbjct: 930  PLGERGPP--GPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGD 987

Query: 816  PSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPP 855
            P   GPTG  G +       A    G        GG+  P
Sbjct: 988  P---GPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLP 1024



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 52/196 (26%), Positives = 62/196 (31%), Gaps = 37/196 (18%)

Query: 677 GSPGRPAFLRSPGLCGPGPVPG-----------GLSVPTPCGRGAGDF-----------S 714
           G PG P F   PG  GP  +PG           G  +  P     G F           +
Sbjct: 407 GPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQA 466

Query: 715 EADLADRAFPVRG-AGPI--AGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPE 771
           +A L      ++G  GP+   GR    G      L KG    + P  P     Q P  P 
Sbjct: 467 QAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGL-KGEEGAEGPQGPRG--LQGPHGPP 523

Query: 772 KETEAPRLRGRATAVAPRPLPAAP------GFSGLCVLQPFPARSRGLGVPSQQGPTGSP 825
                    GR  A   R LP         GF GL  L     +    G   Q GP G  
Sbjct: 524 GRVGK---MGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGED 580

Query: 826 GCRDRASAPRAGAEAG 841
           G R     P    +AG
Sbjct: 581 GERGAEGPPGPTGQAG 596



 Score = 30.4 bits (67), Expect = 7.4
 Identities = 28/98 (28%), Positives = 33/98 (33%), Gaps = 28/98 (28%)

Query: 730 PIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPR 789
           P AG +  +G    A + KG   E PP +P       P  P                   
Sbjct: 370 PGAGEKGAKGEP--AVIEKGQQFEGPPGAPGPQGVVGPSGP------------------- 408

Query: 790 PLPAAPGFSGLCVLQPFPARSRGL-GVPSQQGPTGSPG 826
             P  PGF G     P P    GL G+P   G  G PG
Sbjct: 409 --PGPPGFPG----DPGPPGPAGLPGIPGIDGIRGPPG 440


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 124/463 (26%), Positives = 147/463 (31%), Gaps = 119/463 (25%)

Query: 430 AGGIEAAVLLRGARAGETTPLGEARGPCWKARGAVPSGR-------LRGRPGRV------ 476
           A GI  A    GAR G + P G    P  K     P           +G PG V      
Sbjct: 402 APGIAGAPGFPGAR-GPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPP 460

Query: 477 --AGASGRRGASQARGGTGRAPARLRRG----RGMPGRVGNGVGEGRGASEPEGEPEPRA 530
             AG  G+RGA    G TG       RG    RG PG   +GV   +G +   G P P A
Sbjct: 461 GPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPG--ADGVAGPKGPAGERGSPGP-A 517

Query: 531 RADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAGSGVQRAL 590
                  +AG      LP  A+ L G        G     G      RPG  G    R  
Sbjct: 518 GPKGSPGEAGRPGEAGLPG-AKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGAR-- 574

Query: 591 ALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQG 650
                   G    +  P  +  +   G    R +            +GP       GAQG
Sbjct: 575 --------GQAGVMGFPGPKGAAGEPGKAGERGVP------GPPGAVGPAGKDGEAGAQG 620

Query: 651 PRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGP---------VPGGLS 701
           P       P     E G       E+G  G P F   PG  GP           VPG L 
Sbjct: 621 PPG-----PAGPAGERG-------EQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLG 668

Query: 702 VPTPCG-RGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPA 760
            P P G RG          +R FP        G R  +G               PP    
Sbjct: 669 APGPSGARG----------ERGFP--------GERGVQG---------------PPG--- 692

Query: 761 ASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQG 820
                 P  P     AP   G   A      P APG  G   LQ         G+P ++G
Sbjct: 693 ------PAGPRGANGAP---GNDGAKGDAGAPGAPGSQGAPGLQ---------GMPGERG 734

Query: 821 PTGSPGCR-DRASAPRAGAEAGSMETFLRNGGLYPPPSPRAPA 862
             G PG + DR  A   GA+    +  +R  GL  P  P  PA
Sbjct: 735 AAGLPGPKGDRGDAGPKGADGSPGKDGVR--GLTGPIGPPGPA 775



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 118/447 (26%), Positives = 142/447 (31%), Gaps = 109/447 (24%)

Query: 471 GRPGRVAGASGRRGASQARGGTGRAPARLRRGRGMPGRVGN----GVGEGRGASEPEGEP 526
           G+PGR  G  G  G   ARG  G A        G+PG  G+    G+   +G + P G P
Sbjct: 236 GKPGR-PGERGPPGPQGARGLPGTA--------GLPGMKGHRGFSGLDGAKGDAGPAG-P 285

Query: 527 EPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAGSGV 586
           +    +  E    G    + LP    R G   P     G     G   AA  PG  G   
Sbjct: 286 KGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPA----GARGNDGATGAAGPPGPTGPAG 341

Query: 587 QRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLG-------P 639
                 A    G        P   RGS   G   VR          A    G       P
Sbjct: 342 PPGFPGAVGAKGE-----AGPQGPRGSE--GPQGVRGEPGPPGPAGAAGPAGNPGADGQP 394

Query: 640 GSFGAGLGAQGPRSSTPECPVVNGSEW--GLAAPLSPE--RGSPGRPAFLRSPGLCG-PG 694
           G+ GA  GA G  +  P  P   G     G   P  P+   G PG P      G  G PG
Sbjct: 395 GAKGAN-GAPGI-AGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPG 452

Query: 695 PV--------------------PGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGR 734
           PV                    PG   +P P G   G  S      R FP  GA  +AG 
Sbjct: 453 PVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGS------RGFP--GADGVAGP 504

Query: 735 RRRRGWTFAAALRKGAPREQPPASPAASPCQAPR-------------------APEKETE 775
           +   G        +G+P    PA P  SP +A R                    P+ +T 
Sbjct: 505 KGPAG-------ERGSPG---PAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTG 554

Query: 776 APRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPR 835
            P   G+     P   P  PG  G   +  FP      G P + G  G PG         
Sbjct: 555 PPGPAGQDGRPGP---PGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAG 611

Query: 836 AGAEAGSMETFLRNGGLYPPPSPRAPA 862
              EAG+            PP P  PA
Sbjct: 612 KDGEAGAQ----------GPPGPAGPA 628



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 74/251 (29%), Positives = 85/251 (33%), Gaps = 54/251 (21%)

Query: 647 GAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPC 706
           G +GP+  T           G   P  P  G PGR      PGL GP   PG    P   
Sbjct: 109 GVEGPKGDT-----------GPRGPRGPA-GPPGRDGIPGQPGLPGPPGPPGPPGPPGLG 156

Query: 707 GRGAGDFSEADLADRAFPVRGAGPI--AGRRRRRGWTFAAALR--KGAPREQPPASPAAS 762
           G  A   S          +   GP+  +G R   G   A   +  +G P E  P  P AS
Sbjct: 157 GNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGE--PGEPGAS 214

Query: 763 PCQAPRAPE-------KETEA-----PRLRGRATAVAPRPLPAAPGFSGLCVLQPF---- 806
               PR P         + EA     P  RG       R LP   G  G+   + F    
Sbjct: 215 GPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLD 274

Query: 807 -------PARSRGL-------GVPSQQGPTGSPGCRDRASAP-RAGAEAGSMETFLRNGG 851
                  PA  +G        G P Q GP G PG R R  AP  AGA      T     G
Sbjct: 275 GAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGAT-----G 329

Query: 852 LYPPPSPRAPA 862
              PP P  PA
Sbjct: 330 AAGPPGPTGPA 340



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 137/489 (28%), Positives = 157/489 (32%), Gaps = 96/489 (19%)

Query: 426  AVGLAGGIEAAVLLRGARAGETTPLGEARGPCWKARGAVPSGR--LRGRPGRV-----AG 478
            AVG AG        +   AG   P G A GP  +     P+G    +G PG       AG
Sbjct: 606  AVGPAG--------KDGEAGAQGPPGPA-GPAGERGEQGPAGSPGFQGLPGPAGPPGEAG 656

Query: 479  ASGRRGASQARGGTGRAPARLRRG-------RGMPGRVG----NGVGEGRGASEPEGEPE 527
              G +G     G  G + AR  RG       +G PG  G    NG     GA    G P 
Sbjct: 657  KPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPG 716

Query: 528  PRARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAG---- 583
                        G   LQ +P   ER     PG    G    AG   A   PG  G    
Sbjct: 717  APG-------SQGAPGLQGMP--GERGAAGLPGP--KGDRGDAGPKGADGSPGKDGVRGL 765

Query: 584  SGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLG----- 638
            +G       A A      +    P    G+R A   R      G A  A           
Sbjct: 766  TGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGA 825

Query: 639  ---PGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAP-LSPERGSPGRPAFLRSPGLCG-- 692
               PG  GA   A  P  + P  P   G    + AP     RGS G P     PG  G  
Sbjct: 826  KGEPGDAGAKGDAGPPGPAGPAGPP--GPIGNVGAPGAKGARGSAGPPGATGFPGAAGRV 883

Query: 693  --PGPV--PGGLSVPTPCGR--GAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAAL 746
              PGP    G    P P G+  G G   E   A R   V   GP              A 
Sbjct: 884  GPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPG-----------PAG 932

Query: 747  RKGAPREQPPASPAASPCQAPRAPEKETEA-PRLRGRATAVAPRPLPAAPGFSGLCVLQP 805
             KG+P    PA    +P     A ++     P  RG       R  P  PG SG    Q 
Sbjct: 933  EKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGE------RGFPGLPGPSGEPGKQG 986

Query: 806  FPARSRGLGVPSQQGP---TGSPGCRDRASAPRA----------GAEAGSMETFLRNGGL 852
                S   G P   GP    G PG   R  AP A          GA+    ET    G  
Sbjct: 987  PSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGET----GPA 1042

Query: 853  YPPPSPRAP 861
             PP +P AP
Sbjct: 1043 GPPGAPGAP 1051



 Score = 50.1 bits (118), Expect = 9e-06
 Identities = 121/440 (27%), Positives = 142/440 (32%), Gaps = 88/440 (20%)

Query: 455 GPCWKARGAVPSGRLRGRPGRVA--GASGRRGASQARGGTGRAPARLRRGR----GMPGR 508
           GP  K     P+G+  GRPG     GA G+ G     G  G A    + G     G PG 
Sbjct: 548 GPDGKTGPPGPAGQ-DGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGA 606

Query: 509 VGNGVGEGR-GASEPEGEPEPRARADLEVLQAGFERLQSLPELAERLG--GRCPGQVAHG 565
           VG    +G  GA  P G   P      E   AG    Q LP  A   G  G+   Q   G
Sbjct: 607 VGPAGKDGEAGAQGPPGPAGPAGERG-EQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPG 665

Query: 566 VLARAGLLAAAARPGLAGS-GVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREI 624
            L   G   A    G  G  GVQ                   P    G R A      + 
Sbjct: 666 DLGAPGPSGARGERGFPGERGVQ------------------GPPGPAGPRGANGAPGNDG 707

Query: 625 EFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAF 684
             G A         PGS GA  G QG        P   G+  GL  P   +RG  G    
Sbjct: 708 AKGDAGAPG----APGSQGAP-GLQG-------MPGERGAA-GLPGPKG-DRGDAGPKGA 753

Query: 685 LRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAA 744
             SPG  G   + G +  P P G   GD  E+  +  A P  GA    G R   G    A
Sbjct: 754 DGSPGKDGVRGLTGPIGPPGPAG-APGDKGESGPSGPAGPT-GARGAPGDRGEPGPPGPA 811

Query: 745 ALR-----------KGAPREQPPASPAASPCQA----PRAPEKETEAPRLRGRATAVAPR 789
                         KG P +      A  P  A    P  P     AP  +G   +  P 
Sbjct: 812 GFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGP- 870

Query: 790 PLPAAPGFSGLC--VLQPFPARSRG----------------------LGVPSQQGPTGSP 825
             P A GF G    V  P P+ + G                       G P + GP G P
Sbjct: 871 --PGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPP 928

Query: 826 GCRDRASAPRAGAEAGSMET 845
           G      +P A   AG+  T
Sbjct: 929 GPAGEKGSPGADGPAGAPGT 948



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 132/470 (28%), Positives = 155/470 (32%), Gaps = 64/470 (13%)

Query: 430  AGGIEAAVLLRGARAGETTPLGEARGPCWK--ARGAVPSGRLRGRPGRV-----AGASGR 482
            A G++     RGA AG   P G+ RG      A G+     +RG  G +     AGA G 
Sbjct: 723  APGLQGMPGERGA-AGLPGPKGD-RGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGD 780

Query: 483  RGASQARGGTGRAPARLRRG-RGMPGRVGNGVGEGRGASEPEGEPEPRARADLEVLQAGF 541
            +G S   G  G   AR   G RG PG  G        A  P  + +P A+   E   AG 
Sbjct: 781  KGESGPSGPAGPTGARGAPGDRGEPGPPG----PAGFAGPPGADGQPGAKG--EPGDAGA 834

Query: 542  ERLQSLPELAERLGGRCP-GQV----AHGVLARAGLLAAAARPGLAGSGVQRALALAAAQ 596
            +     P  A   G   P G V    A G    AG   A   PG AG       +  A  
Sbjct: 835  KGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGP 894

Query: 597  LGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSS-- 654
             G            +G R       R  E G          GP       GA GP  +  
Sbjct: 895  PG--PPGPAGKEGGKGPRGETGPAGRPGEVGPP-----GPPGPAGEKGSPGADGPAGAPG 947

Query: 655  TPECPVVNGSEWGLAAP-LSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCG----RG 709
            TP    + G    +  P    ERG PG P     PG  GP    G    P P G     G
Sbjct: 948  TPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAG 1007

Query: 710  AGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAAL--RKGAPREQPPASPAASPCQ-- 765
                S  + A  A    G     G +  RG T  A      GAP    P  PA       
Sbjct: 1008 PPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRG 1067

Query: 766  --APRAPEKETEAPRLRGRATAVAP------------RPLPAAPGFSGLCVLQPFPARSR 811
               P  P         RG A    P            R +    GFSGL    P P    
Sbjct: 1068 ETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGL-QGPPGPP--- 1123

Query: 812  GLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNG--GLYPPPSPR 859
              G P +QGP+G+ G       P     AG+      NG  G   PP PR
Sbjct: 1124 --GSPGEQGPSGASGPAGPRGPP---GSAGAPGKDGLNGLPGPIGPPGPR 1168



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 62/205 (30%), Positives = 72/205 (35%), Gaps = 32/205 (15%)

Query: 639 PGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPG 698
           PG  GA  G  GPR   P  P  NG +         E G PGRP     PG  G   +PG
Sbjct: 208 PGEPGAS-GPMGPRGP-PGPPGKNGDDG--------EAGKPGRPGERGPPGPQGARGLPG 257

Query: 699 GLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPAS 758
              +P    +G   FS  D A        AGP AG +   G    +    GAP +     
Sbjct: 258 TAGLPGM--KGHRGFSGLDGAKG-----DAGP-AGPKGEPG----SPGENGAPGQM---G 302

Query: 759 PAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAP-GFSGLCVLQPFPARSRGLGVPS 817
           P   P +  R         R    AT  A  P P  P G  G      FP      G   
Sbjct: 303 PRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPG------FPGAVGAKGEAG 356

Query: 818 QQGPTGSPGCRDRASAPRAGAEAGS 842
            QGP GS G +     P     AG+
Sbjct: 357 PQGPRGSEGPQGVRGEPGPPGPAGA 381



 Score = 31.2 bits (69), Expect = 4.4
 Identities = 30/90 (33%), Positives = 35/90 (38%), Gaps = 9/90 (10%)

Query: 35  AAQAGGEGGRAQPGLPCSVDLATGLEGPLGGPAVDLDVGFSPGDDIAGQSLGAAGGQVVH 94
           A + G  G R +PG        TGL GP G        GF   D +AG   G AG +   
Sbjct: 463 AGEEGKRGARGEPG-------PTGLPGPPGERGGPGSRGFPGADGVAGPK-GPAGERGSP 514

Query: 95  LPGGQLAVPDVEVGQLTHKCLGGIKPTTQS 124
            P G    P  E G+     L G K  T S
Sbjct: 515 GPAGPKGSPG-EAGRPGEAGLPGAKGLTGS 543


>gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo
            sapiens]
          Length = 1691

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 96/372 (25%), Positives = 132/372 (35%), Gaps = 64/372 (17%)

Query: 469  LRGRPGRVAGASGRRGASQARGGTGRAPARLRRGRGMPGRVG--NGVGEGRGASEPEGEP 526
            +RG PG + G+SG  G     G +G     +R   G+PG  G     G+     E  G P
Sbjct: 1025 IRGLPG-LKGSSGITGFPGMPGESGSQG--IRGSPGLPGASGLPGLKGDNGQTVEISGSP 1081

Query: 527  EPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVAH----GVLARAGLLAAAARPGLA 582
             P+ +      ++GF+  +    L   +G   PG        GV    GL  A   PG+A
Sbjct: 1082 GPKGQPG----ESGFKGTKGRDGLIGNIG--FPGNKGEDGKVGVSGDVGLPGAPGFPGVA 1135

Query: 583  GSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSF 642
            G   +  L  ++   G     + SP L       G   +  +           T GP   
Sbjct: 1136 GMRGEPGLPGSSGHQGAIGP-LGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSIT 1194

Query: 643  GAG--LGAQGPRSSTPECPVVNGSEWGLAAPLSPE-RGSPGRPAFLRSPGLCGPGPVPG- 698
            G     G  GP+       +      G+ AP  P  RG  G   F   PGL GP  +PG 
Sbjct: 1195 GVPGPAGLPGPKGEKGYPGI------GIGAPGKPGLRGQKGDRGF---PGLQGPAGLPGA 1245

Query: 699  -GLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPA 757
             G+S+P+      GD              G   + G R R G                PA
Sbjct: 1246 PGISLPSLIAGQPGD-------------PGRPGLDGERGRPG----------------PA 1276

Query: 758  SPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGL---CVLQPFPARSRGLG 814
             P   P   P + + +T  P   G      P+     PGFSGL     L+        +G
Sbjct: 1277 GPPGPP--GPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMG 1334

Query: 815  VPSQQGPTGSPG 826
             P + GP G PG
Sbjct: 1335 TPGKVGPPGDPG 1346



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 97/391 (24%), Positives = 128/391 (32%), Gaps = 71/391 (18%)

Query: 471  GRPGR--VAGASGRRGASQARGGTGRAPARLRRGRGMPGRVG-NGVGEGRGASEPEGEPE 527
            G PG+  + G  G  G   ++G TG          G PG  G  G+   +G     G P 
Sbjct: 727  GLPGKDGLPGMIGSPGLPGSKGATGDI---FGAENGAPGEQGLQGLTGHKGFLGDSGLP- 782

Query: 528  PRARADLEVLQAGFERLQSLPELAERLGGR----CPGQVA----------HGVLARAGLL 573
                        G + +   P L    G R     PGQV           +G+  ++GL 
Sbjct: 783  ------------GLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLP 830

Query: 574  AAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAA 633
             A   PG++G   ++         G     +V   L       GN  +  ++ GS     
Sbjct: 831  GAPGFPGISGHPGKKGTRGKKGPPGS----IVKKGLPGLKGLPGNPGLVGLK-GS----- 880

Query: 634  LNTLGPGSFG-AGLGA-QGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLC 691
                 PGS G AGL A  GP+        V               G PG P     PG  
Sbjct: 881  -----PGSPGVAGLPALSGPKGEKGSVGFV---------------GFPGIPGLPGIPGTR 920

Query: 692  GPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAP 751
            G   +PG      P GR     +  +  DR  P     P   R     W       +G+ 
Sbjct: 921  GLKGIPGSTGKMGPSGRAG---TPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSA 977

Query: 752  REQPPASPAASPCQAPR-APEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARS 810
                   P     +A R  P     AP L G    V+ +P P  PGF G+  L      S
Sbjct: 978  GSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGP--PGFMGIRGLPGLKGSS 1035

Query: 811  RGLGVPSQQGPTGSPGCRDRASAPRAGAEAG 841
               G P   G +GS G R     P A    G
Sbjct: 1036 GITGFPGMPGESGSQGIRGSPGLPGASGLPG 1066



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 95/381 (24%), Positives = 125/381 (32%), Gaps = 88/381 (23%)

Query: 457 CWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLRRGRGMPGRVGNGVGEG 516
           C+  +GA      RGRPG + G  G  G     G TG +   L+  RG PG +G      
Sbjct: 42  CFPEKGA------RGRPGPI-GIQGPTGPQGFTGSTGLSG--LKGERGFPGLLGPY--GP 90

Query: 517 RGASEPEGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAA 576
           +G   P G P             GF  +  +P    + G R P                 
Sbjct: 91  KGDKGPMGVP-------------GFLGINGIPGHPGQPGPRGP----------------- 120

Query: 577 ARPGLAG-SGVQRALALAAAQLGGWTTCVVSPNL--RRGSRRAGNHRVREIEFGSALLAA 633
             PGL G +G Q A+        G+   +  P L  ++GS+            G  +LA 
Sbjct: 121 --PGLDGCNGTQGAVGFPGPD--GYPGLLGPPGLPGQKGSK------------GDPVLA- 163

Query: 634 LNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGP 693
                PGSF    G        P  P ++G      AP  P    P  P     PGL GP
Sbjct: 164 -----PGSFKGMKG-------DPGLPGLDGITGPQGAPGFPGAVGPAGP-----PGLQGP 206

Query: 694 GPVPGGLSVPTPCGRGAGDFSEADLADRAFP-VRGAGPIAGRRRRRGWTFAAALRKGAPR 752
              PG L      G G     +    D   P   G  P  G     G+       KG P 
Sbjct: 207 PGPPGPLGPDGNMGLGFQG-EKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPG 265

Query: 753 EQ-------PPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQP 805
            +       PP  P        +  + E   P L G    +    +   PG  G      
Sbjct: 266 PKGFPGISGPPGFPGLGTT-GEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLG 324

Query: 806 FPARSRGLGVPSQQGPTGSPG 826
           FP  +   G+  Q+G  G PG
Sbjct: 325 FPGLNGFQGIEGQKGDIGLPG 345



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 95/399 (23%), Positives = 135/399 (33%), Gaps = 66/399 (16%)

Query: 469  LRGRPGRVAGASGRRGASQARGGTGR-------APARLRRGRGMPGRVG-NGVGEGRGAS 520
            + G+PG + G  G RG+    G  G+        P  ++   G+PG  G  G+    G  
Sbjct: 787  VHGKPG-LLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKK 845

Query: 521  EPEGEPEPRARADLEVLQAGFERLQSLPELAERLGGR----CPGQVA-------HGVLAR 569
               G+  P       +++ G   L+ LP     +G +     PG           G    
Sbjct: 846  GTRGKKGPPG----SIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGS 901

Query: 570  AGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFG-- 627
             G +     PGL G    R L       G      + P+ R G+      R      G  
Sbjct: 902  VGFVGFPGIPGLPGIPGTRGLKGIPGSTGK-----MGPSGRAGTPGEKGDRGNPGPVGIP 956

Query: 628  ------SALLAALNTLGPGSFGAGLGAQGPRSSTPEC-----PVVNGSEWGLAAPLSPER 676
                  S L    +    GS G+  G  GPR    E      P + G+  GL   +    
Sbjct: 957  SPRRPMSNLWLKGDKGSQGSAGSN-GFPGPRGDKGEAGRPGPPGLPGAP-GLPGIIKGVS 1014

Query: 677  GSPGRPAFLRS---PGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAG 733
            G PG P F+     PGL G   + G   +P   G      S+        P  GA  + G
Sbjct: 1015 GKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESG------SQGIRGSPGLP--GASGLPG 1066

Query: 734  RRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEK---ETEAPRLRGRATAVAPRP 790
             +   G T   +   G+P   P   P  S  +  +  +        P  +G    V    
Sbjct: 1067 LKGDNGQTVEIS---GSPG--PKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSG 1121

Query: 791  ---LPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPG 826
               LP APGF G+  ++  P      G     GP GSPG
Sbjct: 1122 DVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPG 1160



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 100/373 (26%), Positives = 122/373 (32%), Gaps = 41/373 (10%)

Query: 470  RGRPGRVAGASGRRGASQARGGTGRAPARLRRGRGMPGRVGNGVGEGRGASEPEGEPEPR 529
            +G  G+V G SG  G   A G  G   A +R   G+PG  G+     +GA  P G P   
Sbjct: 1111 KGEDGKV-GVSGDVGLPGAPGFPG--VAGMRGEPGLPGSSGH-----QGAIGPLGSPGLI 1162

Query: 530  ARADLEVLQAGFERLQSLPELAERLGGR-CPGQVAHGVLARAGLLAAAARPGLAGSGVQR 588
                      GF  L  L  L    G    PG    GV   AGL       G  G G+  
Sbjct: 1163 GPKGFP----GFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIG- 1217

Query: 589  ALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGA 648
              A     L G       P L+     AG      I   S +       G        G 
Sbjct: 1218 --APGKPGLRGQKGDRGFPGLQGP---AGLPGAPGISLPSLIAGQPGDPGRPGLDGERGR 1272

Query: 649  QGPRSST-PECPVVNGSEWG------LAAPLSPERGSPGRPAFLRSPG---LCGPGPVPG 698
             GP     P  P  N  + G      +  P  P +G  G P F   PG   L G    PG
Sbjct: 1273 PGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGP-KGDQGIPGFSGLPGELGLKGMRGEPG 1331

Query: 699  GLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQP--- 755
             +  P   G   GD     +  +A P RG+  + G   +     A  +  G P   P   
Sbjct: 1332 FMGTPGKVGP-PGDPGFPGMKGKAGP-RGSSGLQGDPGQTPTAEAVQVPPG-PLGLPGID 1388

Query: 756  --PASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGL 813
              P        Q P   +     P + G+     P  LP  PG  G   L          
Sbjct: 1389 GIPGLTGDPGAQGPVGLQGSKGLPGIPGKD---GPSGLPGPPGALGDPGLPGLQGPPGFE 1445

Query: 814  GVPSQQGPTGSPG 826
            G P QQGP G PG
Sbjct: 1446 GAPGQQGPFGMPG 1458



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 115/461 (24%), Positives = 144/461 (31%), Gaps = 90/461 (19%)

Query: 454 RGP-----CWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLRRGRGMPGR 508
           RGP     C   +GAV      G PG + G  G  G   ++G    AP   +  +G PG 
Sbjct: 118 RGPPGLDGCNGTQGAVGFPGPDGYPG-LLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGL 176

Query: 509 VGNGVGEGRGASEPEGEPE-PRARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVL 567
            G       G + P+G P  P A     V  AG   LQ  P     LG    G +  G  
Sbjct: 177 PGLD-----GITGPQGAPGFPGA-----VGPAGPPGLQGPPGPPGPLGP--DGNMGLGFQ 224

Query: 568 ARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFG 627
              G+      PG AG               G    +  P  ++GS+     +      G
Sbjct: 225 GEKGVKGDVGLPGPAGPPPST----------GELEFMGFPKGKKGSKGEPGPKGFPGISG 274

Query: 628 SALLAALNTLG-------------PGSFG--AGLGAQGP-----RSSTPECPVVNG---- 663
                 L T G             PG  G     G QGP     +  T   P +NG    
Sbjct: 275 PPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGI 334

Query: 664 ----SEWGLAAP----------LSPERGSPGRPAF--LRSP----GLCGPGPVPG--GLS 701
                + GL  P          +S   G PG P    L+      GL GP  VPG   LS
Sbjct: 335 EGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALS 394

Query: 702 -VPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPA 760
            VP   G       + D  +      GA  + GR              G P    P  P 
Sbjct: 395 GVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGR-------------DGLPGPPGPPGPP 441

Query: 761 ASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQG 820
           +   +      KE+  P LRG         L    G SG C        +   G P   G
Sbjct: 442 SPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPG 501

Query: 821 PTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAP 861
           P G  G      A R    +G  +      GL  P  P  P
Sbjct: 502 PWGLIGLPGLKGA-RGDRGSGGAQGPAGAPGLVGPLGPSGP 541



 Score = 38.1 bits (87), Expect = 0.036
 Identities = 92/370 (24%), Positives = 118/370 (31%), Gaps = 87/370 (23%)

Query: 476 VAGASGRRGASQARGGTGRAPARLRRGRGMPGRVGNGVGEGRGASEPEGEPEPRARAD-L 534
           V GA G +G    +G  G          G+PGR G       G   P G P P    + L
Sbjct: 396 VPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLP-----GPPGPPGPPSPEFETETL 450

Query: 535 EVLQAGFERLQSLPELAERLGGR----------CPGQVAH----GVLARAGLLAAAARPG 580
              ++GF  L+        LG +          C G V +    G     G       PG
Sbjct: 451 HNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPG 510

Query: 581 LAGSGVQRALALAAAQLGG-WTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGP 639
           L G+   R    A    G       + P+  +G +            G  +L+ +  + P
Sbjct: 511 LKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKK------------GEPILSTIQGM-P 557

Query: 640 GSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGG 699
           G  G   G+QG R    E P  +G       P  P  G  G P     PGL      PG 
Sbjct: 558 GDRGDS-GSQGFRGVIGE-PGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGL------PGE 609

Query: 700 LSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQ--PPA 757
              P P G                P  G   + G R   G       + G P +Q  P +
Sbjct: 610 KGHPGPPG---------------LPGNGLPGLPGPRGLPG----DKGKDGLPGQQGLPGS 650

Query: 758 SPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGL-GVP 816
                PC  P +                  P   P  PGF G       P  SRGL G P
Sbjct: 651 KGITLPCIIPGS----------------YGPSGFPGTPGFPG-------PKGSRGLPGTP 687

Query: 817 SQQGPTGSPG 826
            Q G +GS G
Sbjct: 688 GQPGSSGSKG 697



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 53/211 (25%), Positives = 70/211 (33%), Gaps = 51/211 (24%)

Query: 675 ERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADR---------AFP- 724
           + G PG       PGL GP    G    P   G+     S      +          FP 
Sbjct: 778 DSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPG 837

Query: 725 VRGAGPIAGRRRRRGWTFAAALRKGAP-------------REQPPASPAASPCQAPRAPE 771
           + G     G R ++G    + ++KG P              +  P SP  +   A   P+
Sbjct: 838 ISGHPGKKGTRGKKG-PPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPK 896

Query: 772 KETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGL-GVPSQQGPTGSPGCRDR 830
            E      +G    V    +P  PG  G          +RGL G+P   G TG  G   R
Sbjct: 897 GE------KGSVGFVGFPGIPGLPGIPG----------TRGLKGIP---GSTGKMGPSGR 937

Query: 831 ASAPRAGAEAGSMETFLRNGGLYPPPSPRAP 861
           A  P    + G       N G    PSPR P
Sbjct: 938 AGTPGEKGDRG-------NPGPVGIPSPRRP 961


>gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo
            sapiens]
          Length = 1690

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 96/372 (25%), Positives = 132/372 (35%), Gaps = 64/372 (17%)

Query: 469  LRGRPGRVAGASGRRGASQARGGTGRAPARLRRGRGMPGRVG--NGVGEGRGASEPEGEP 526
            +RG PG + G+SG  G     G +G     +R   G+PG  G     G+     E  G P
Sbjct: 1024 IRGLPG-LKGSSGITGFPGMPGESGSQG--IRGSPGLPGASGLPGLKGDNGQTVEISGSP 1080

Query: 527  EPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVAH----GVLARAGLLAAAARPGLA 582
             P+ +      ++GF+  +    L   +G   PG        GV    GL  A   PG+A
Sbjct: 1081 GPKGQPG----ESGFKGTKGRDGLIGNIG--FPGNKGEDGKVGVSGDVGLPGAPGFPGVA 1134

Query: 583  GSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSF 642
            G   +  L  ++   G     + SP L       G   +  +           T GP   
Sbjct: 1135 GMRGEPGLPGSSGHQGAIGP-LGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSIT 1193

Query: 643  GAG--LGAQGPRSSTPECPVVNGSEWGLAAPLSPE-RGSPGRPAFLRSPGLCGPGPVPG- 698
            G     G  GP+       +      G+ AP  P  RG  G   F   PGL GP  +PG 
Sbjct: 1194 GVPGPAGLPGPKGEKGYPGI------GIGAPGKPGLRGQKGDRGF---PGLQGPAGLPGA 1244

Query: 699  -GLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPA 757
             G+S+P+      GD              G   + G R R G                PA
Sbjct: 1245 PGISLPSLIAGQPGD-------------PGRPGLDGERGRPG----------------PA 1275

Query: 758  SPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGL---CVLQPFPARSRGLG 814
             P   P   P + + +T  P   G      P+     PGFSGL     L+        +G
Sbjct: 1276 GPPGPP--GPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMG 1333

Query: 815  VPSQQGPTGSPG 826
             P + GP G PG
Sbjct: 1334 TPGKVGPPGDPG 1345



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 97/391 (24%), Positives = 128/391 (32%), Gaps = 71/391 (18%)

Query: 471  GRPGR--VAGASGRRGASQARGGTGRAPARLRRGRGMPGRVG-NGVGEGRGASEPEGEPE 527
            G PG+  + G  G  G   ++G TG          G PG  G  G+   +G     G P 
Sbjct: 726  GLPGKDGLPGMIGSPGLPGSKGATGDI---FGAENGAPGEQGLQGLTGHKGFLGDSGLP- 781

Query: 528  PRARADLEVLQAGFERLQSLPELAERLGGR----CPGQVA----------HGVLARAGLL 573
                        G + +   P L    G R     PGQV           +G+  ++GL 
Sbjct: 782  ------------GLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLP 829

Query: 574  AAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAA 633
             A   PG++G   ++         G     +V   L       GN  +  ++ GS     
Sbjct: 830  GAPGFPGISGHPGKKGTRGKKGPPGS----IVKKGLPGLKGLPGNPGLVGLK-GS----- 879

Query: 634  LNTLGPGSFG-AGLGA-QGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLC 691
                 PGS G AGL A  GP+        V               G PG P     PG  
Sbjct: 880  -----PGSPGVAGLPALSGPKGEKGSVGFV---------------GFPGIPGLPGIPGTR 919

Query: 692  GPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAP 751
            G   +PG      P GR     +  +  DR  P     P   R     W       +G+ 
Sbjct: 920  GLKGIPGSTGKMGPSGRAG---TPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSA 976

Query: 752  REQPPASPAASPCQAPR-APEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARS 810
                   P     +A R  P     AP L G    V+ +P P  PGF G+  L      S
Sbjct: 977  GSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGP--PGFMGIRGLPGLKGSS 1034

Query: 811  RGLGVPSQQGPTGSPGCRDRASAPRAGAEAG 841
               G P   G +GS G R     P A    G
Sbjct: 1035 GITGFPGMPGESGSQGIRGSPGLPGASGLPG 1065



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 109/433 (25%), Positives = 143/433 (33%), Gaps = 100/433 (23%)

Query: 405 VHPGQHLPLQLIDLALQQILEAVGLAGGIEAAVLLRGARAGETTPLGEARGPCWKARGAV 464
           +HPG  L L L+ L L + L A G            G   G     G  +  C+  +GA 
Sbjct: 1   MHPG--LWLLLVTLCLTEELAAAGEKS--------YGKPCGGQDCSGSCQ--CFPEKGA- 47

Query: 465 PSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLRRGRGMPGRVGNGVGEGRGASEPEG 524
                RGRPG + G  G  G     G TG +   L+  RG PG +G      +G   P G
Sbjct: 48  -----RGRPGPI-GIQGPTGPQGFTGSTGLSG--LKGERGFPGLLGPY--GPKGDKGPMG 97

Query: 525 EPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAG- 583
            P             GF  +  +P    + G R P                   PGL G 
Sbjct: 98  VP-------------GFLGINGIPGHPGQPGPRGP-------------------PGLDGC 125

Query: 584 SGVQRALALAAAQLGGWTTCVVSPNL--RRGSRRAGNHRVREIEFGSALLAALNTLGPGS 641
           +G Q A+        G+   +  P L  ++GS+            G  +LA      PGS
Sbjct: 126 NGTQGAVGFPGPD--GYPGLLGPPGLPGQKGSK------------GDPVLA------PGS 165

Query: 642 FGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLS 701
           F    G        P  P ++G      AP  P    P  P     PGL GP   PG L 
Sbjct: 166 FKGMKG-------DPGLPGLDGITGPQGAPGFPGAVGPAGP-----PGLQGPPGPPGPLG 213

Query: 702 VPTPCGRGAGDFSEADLADRAFP-VRGAGPIAGRRRRRGWTFAAALRKGAPREQ------ 754
                G G     +    D   P   G  P  G     G+       KG P  +      
Sbjct: 214 PDGNMGLGFQG-EKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGIS 272

Query: 755 -PPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGL 813
            PP  P        +  + E   P L G    +    +   PG  G      FP  +   
Sbjct: 273 GPPGFPGLGTT-GEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQ 331

Query: 814 GVPSQQGPTGSPG 826
           G+  Q+G  G PG
Sbjct: 332 GIEGQKGDIGLPG 344



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 95/399 (23%), Positives = 135/399 (33%), Gaps = 66/399 (16%)

Query: 469  LRGRPGRVAGASGRRGASQARGGTGR-------APARLRRGRGMPGRVG-NGVGEGRGAS 520
            + G+PG + G  G RG+    G  G+        P  ++   G+PG  G  G+    G  
Sbjct: 786  VHGKPG-LLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKK 844

Query: 521  EPEGEPEPRARADLEVLQAGFERLQSLPELAERLGGR----CPGQVA-------HGVLAR 569
               G+  P       +++ G   L+ LP     +G +     PG           G    
Sbjct: 845  GTRGKKGPPG----SIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGS 900

Query: 570  AGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFG-- 627
             G +     PGL G    R L       G      + P+ R G+      R      G  
Sbjct: 901  VGFVGFPGIPGLPGIPGTRGLKGIPGSTGK-----MGPSGRAGTPGEKGDRGNPGPVGIP 955

Query: 628  ------SALLAALNTLGPGSFGAGLGAQGPRSSTPEC-----PVVNGSEWGLAAPLSPER 676
                  S L    +    GS G+  G  GPR    E      P + G+  GL   +    
Sbjct: 956  SPRRPMSNLWLKGDKGSQGSAGSN-GFPGPRGDKGEAGRPGPPGLPGAP-GLPGIIKGVS 1013

Query: 677  GSPGRPAFLRS---PGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAG 733
            G PG P F+     PGL G   + G   +P   G      S+        P  GA  + G
Sbjct: 1014 GKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESG------SQGIRGSPGLP--GASGLPG 1065

Query: 734  RRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEK---ETEAPRLRGRATAVAPRP 790
             +   G T   +   G+P   P   P  S  +  +  +        P  +G    V    
Sbjct: 1066 LKGDNGQTVEIS---GSPG--PKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSG 1120

Query: 791  ---LPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPG 826
               LP APGF G+  ++  P      G     GP GSPG
Sbjct: 1121 DVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPG 1159



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 100/373 (26%), Positives = 122/373 (32%), Gaps = 41/373 (10%)

Query: 470  RGRPGRVAGASGRRGASQARGGTGRAPARLRRGRGMPGRVGNGVGEGRGASEPEGEPEPR 529
            +G  G+V G SG  G   A G  G   A +R   G+PG  G+     +GA  P G P   
Sbjct: 1110 KGEDGKV-GVSGDVGLPGAPGFPG--VAGMRGEPGLPGSSGH-----QGAIGPLGSPGLI 1161

Query: 530  ARADLEVLQAGFERLQSLPELAERLGGR-CPGQVAHGVLARAGLLAAAARPGLAGSGVQR 588
                      GF  L  L  L    G    PG    GV   AGL       G  G G+  
Sbjct: 1162 GPKGFP----GFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIG- 1216

Query: 589  ALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGA 648
              A     L G       P L+     AG      I   S +       G        G 
Sbjct: 1217 --APGKPGLRGQKGDRGFPGLQGP---AGLPGAPGISLPSLIAGQPGDPGRPGLDGERGR 1271

Query: 649  QGPRSST-PECPVVNGSEWG------LAAPLSPERGSPGRPAFLRSPG---LCGPGPVPG 698
             GP     P  P  N  + G      +  P  P +G  G P F   PG   L G    PG
Sbjct: 1272 PGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGP-KGDQGIPGFSGLPGELGLKGMRGEPG 1330

Query: 699  GLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQP--- 755
             +  P   G   GD     +  +A P RG+  + G   +     A  +  G P   P   
Sbjct: 1331 FMGTPGKVGP-PGDPGFPGMKGKAGP-RGSSGLQGDPGQTPTAEAVQVPPG-PLGLPGID 1387

Query: 756  --PASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGL 813
              P        Q P   +     P + G+     P  LP  PG  G   L          
Sbjct: 1388 GIPGLTGDPGAQGPVGLQGSKGLPGIPGKD---GPSGLPGPPGALGDPGLPGLQGPPGFE 1444

Query: 814  GVPSQQGPTGSPG 826
            G P QQGP G PG
Sbjct: 1445 GAPGQQGPFGMPG 1457



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 115/461 (24%), Positives = 144/461 (31%), Gaps = 90/461 (19%)

Query: 454 RGP-----CWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLRRGRGMPGR 508
           RGP     C   +GAV      G PG + G  G  G   ++G    AP   +  +G PG 
Sbjct: 117 RGPPGLDGCNGTQGAVGFPGPDGYPG-LLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGL 175

Query: 509 VGNGVGEGRGASEPEGEPE-PRARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVL 567
            G       G + P+G P  P A     V  AG   LQ  P     LG    G +  G  
Sbjct: 176 PGLD-----GITGPQGAPGFPGA-----VGPAGPPGLQGPPGPPGPLGP--DGNMGLGFQ 223

Query: 568 ARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFG 627
              G+      PG AG               G    +  P  ++GS+     +      G
Sbjct: 224 GEKGVKGDVGLPGPAGPPPST----------GELEFMGFPKGKKGSKGEPGPKGFPGISG 273

Query: 628 SALLAALNTLG-------------PGSFG--AGLGAQGP-----RSSTPECPVVNG---- 663
                 L T G             PG  G     G QGP     +  T   P +NG    
Sbjct: 274 PPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGI 333

Query: 664 ----SEWGLAAP----------LSPERGSPGRPAF--LRSP----GLCGPGPVPG--GLS 701
                + GL  P          +S   G PG P    L+      GL GP  VPG   LS
Sbjct: 334 EGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALS 393

Query: 702 -VPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPA 760
            VP   G       + D  +      GA  + GR              G P    P  P 
Sbjct: 394 GVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGR-------------DGLPGPPGPPGPP 440

Query: 761 ASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQG 820
           +   +      KE+  P LRG         L    G SG C        +   G P   G
Sbjct: 441 SPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPG 500

Query: 821 PTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAP 861
           P G  G      A R    +G  +      GL  P  P  P
Sbjct: 501 PWGLIGLPGLKGA-RGDRGSGGAQGPAGAPGLVGPLGPSGP 540



 Score = 38.1 bits (87), Expect = 0.036
 Identities = 92/370 (24%), Positives = 118/370 (31%), Gaps = 87/370 (23%)

Query: 476 VAGASGRRGASQARGGTGRAPARLRRGRGMPGRVGNGVGEGRGASEPEGEPEPRARAD-L 534
           V GA G +G    +G  G          G+PGR G       G   P G P P    + L
Sbjct: 395 VPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLP-----GPPGPPGPPSPEFETETL 449

Query: 535 EVLQAGFERLQSLPELAERLGGR----------CPGQVAH----GVLARAGLLAAAARPG 580
              ++GF  L+        LG +          C G V +    G     G       PG
Sbjct: 450 HNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPG 509

Query: 581 LAGSGVQRALALAAAQLGG-WTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGP 639
           L G+   R    A    G       + P+  +G +            G  +L+ +  + P
Sbjct: 510 LKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKK------------GEPILSTIQGM-P 556

Query: 640 GSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGG 699
           G  G   G+QG R    E P  +G       P  P  G  G P     PGL      PG 
Sbjct: 557 GDRGDS-GSQGFRGVIGE-PGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGL------PGE 608

Query: 700 LSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQ--PPA 757
              P P G                P  G   + G R   G       + G P +Q  P +
Sbjct: 609 KGHPGPPG---------------LPGNGLPGLPGPRGLPG----DKGKDGLPGQQGLPGS 649

Query: 758 SPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGL-GVP 816
                PC  P +                  P   P  PGF G       P  SRGL G P
Sbjct: 650 KGITLPCIIPGS----------------YGPSGFPGTPGFPG-------PKGSRGLPGTP 686

Query: 817 SQQGPTGSPG 826
            Q G +GS G
Sbjct: 687 GQPGSSGSKG 696



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 53/211 (25%), Positives = 70/211 (33%), Gaps = 51/211 (24%)

Query: 675 ERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADR---------AFP- 724
           + G PG       PGL GP    G    P   G+     S      +          FP 
Sbjct: 777 DSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPG 836

Query: 725 VRGAGPIAGRRRRRGWTFAAALRKGAP-------------REQPPASPAASPCQAPRAPE 771
           + G     G R ++G    + ++KG P              +  P SP  +   A   P+
Sbjct: 837 ISGHPGKKGTRGKKG-PPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPK 895

Query: 772 KETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGL-GVPSQQGPTGSPGCRDR 830
            E      +G    V    +P  PG  G          +RGL G+P   G TG  G   R
Sbjct: 896 GE------KGSVGFVGFPGIPGLPGIPG----------TRGLKGIP---GSTGKMGPSGR 936

Query: 831 ASAPRAGAEAGSMETFLRNGGLYPPPSPRAP 861
           A  P    + G       N G    PSPR P
Sbjct: 937 AGTPGEKGDRG-------NPGPVGIPSPRRP 960


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 108/450 (24%), Positives = 147/450 (32%), Gaps = 51/450 (11%)

Query: 429 LAGGIEAAVLLRGARAGETTP-LGEARGPCWKARGAVPSGRLRGRPGRVAGASGRRGASQ 487
           L G +E+ +    A      P   E R     A GA+ +  + G P   AGA+G   A+ 
Sbjct: 25  LVGSLESQLAASAAHHHHLAPRTPEVRAA---AAGALGNHVVSGSP---AGAAGAGPAAP 78

Query: 488 ARGGTGRAPARLRRGRGMPGRVGNGVGEGRGASEPEGEPEPRARADLEVLQAGFERLQSL 547
           A G  G AP     GR  PG        G G   P G P PR             +L+  
Sbjct: 79  AEGAPGAAPEPPPAGRARPG--------GGGPQRP-GPPSPRRPLVPAGPAPPAAKLRPP 129

Query: 548 PELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSP 607
           PE +    G C        +  A  +AA   P  AG       A  AA+ G        P
Sbjct: 130 PEGS---AGSC------APVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGP 180

Query: 608 NLRRG-SRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQG----PRSSTPECPVVN 662
               G  + AG    + +   +ALL + +   P       G       P+ + P   +  
Sbjct: 181 GPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQT 240

Query: 663 GSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEA------ 716
               G AAP +P   SP       +P    P P P   ++  P G  AG  + A      
Sbjct: 241 PPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPP 300

Query: 717 -------DLADRAFPVRGAGPIAGRRRRRG-WTFAAALRKGAPREQPPASPAASPCQAPR 768
                         P   AG  AG   + G    AAA   G   E P     A+P   P 
Sbjct: 301 AAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAP---PA 357

Query: 769 APEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCR 828
           A       P     +  + P    A P  + +    P PA     G+P       +    
Sbjct: 358 AQTLAASGPASTAASMVIGPTMQGALPSPAAV----PPPAPGTPTGLPKGAAGAVTQSLS 413

Query: 829 DRASAPRAGAEAGSMETFLRNGGLYPPPSP 858
              +A  +G  A    T L      PP +P
Sbjct: 414 RTPTATTSGIRATLTPTVLAPRLPQPPQNP 443


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 124/456 (27%), Positives = 155/456 (33%), Gaps = 69/456 (15%)

Query: 427 VGLAGGIEAAVLLRGAR--------AGETTPLGEARGPCWKARGAVPSGRLRGRPGRVA- 477
           VGL  G    V  RG +        AG T P GE   P     G + S    G PG+   
Sbjct: 208 VGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDP--GPMGPIGSRGPEGPPGKPGE 265

Query: 478 -GASGRRGASQARGGTGRAPARLRRGR-GMPGRVGNGVGEG-RGASEPEGEPEPRARADL 534
            G  GR G     G  G   AR   G  G+PG  G+   +G  G     G P  +  A  
Sbjct: 266 DGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGP 325

Query: 535 EVLQAGFERL--QSLPELAERLGGR-CPGQV-AHGVLARAGLLAAAARPGLAGSGVQRAL 590
                    L  + +P    RLG +  PGQ  AHG+  + G +     PG +G      +
Sbjct: 326 TGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGM 385

Query: 591 ALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAG--LGA 648
              A   G            RG       R      G      L    PG+ G     GA
Sbjct: 386 KGEAGPTGA-----------RGPEGPQGQRGETGPPGPVGSPGL----PGAIGTDGTPGA 430

Query: 649 QGPRSSTPECPVVNGSEWGLAAPLSPE----------RGSPGRPAFLRSPGLCGPGPVPG 698
           +GP  S    P  +G       P SP           RG PG P      G  GP   PG
Sbjct: 431 KGPTGS----PGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPG 486

Query: 699 GLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIA--GRRRRRGWTFAAAL--RKGAPREQ 754
              +  P G    +       D    V   GP+   G    RG+  +  L   KGA  E+
Sbjct: 487 PHGIQGPIGPPGEEGKRGPRGDPG-TVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGER 545

Query: 755 PP---ASPAASPCQAPRAPEKETEAPR-LRGRATAVAPR----PLPAAPGFSGLCVLQPF 806
            P   + P  S     R  E      R L G      P     PL  APG  G    +P 
Sbjct: 546 GPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPL-GAPGEDG----RPG 600

Query: 807 PARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGS 842
           P  S  +G+  Q G  G PG +  +  P    EAG+
Sbjct: 601 PPGS--IGIRGQPGSMGLPGPKGSSGDPGKPGEAGN 634



 Score = 50.1 bits (118), Expect = 9e-06
 Identities = 108/403 (26%), Positives = 132/403 (32%), Gaps = 53/403 (13%)

Query: 455  GPCWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLRRG----RGMPGRVG 510
            GP        P G L+G PG   G +G  G    RGG G   A    G    RG+PG +G
Sbjct: 747  GPSGTPGDTGPPG-LQGMPGE-RGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLG 804

Query: 511  NGVGEGRGASEPEGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARA 570
                   G +  +GEP PR              L   P      G R       G +  A
Sbjct: 805  PP--GPAGPTGEKGEPGPRG-------------LVGPPGSRGNPGSRGENGPT-GAVGFA 848

Query: 571  GLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRA-GNHRVREIEFGSA 629
            G      +PG+ G   +      A   G        P    GS    G + V  ++ G  
Sbjct: 849  GPQGPDGQPGVKGEPGEPGQKGDAGSPG--------PQGLAGSPGPHGPNGVPGLKGGRG 900

Query: 630  LLAALNTLG-PGSFGAGLGAQGPRSST-PECPVVNGSEWGLAAPLSPERGSPGRPAFLRS 687
                    G PGS G  +G  GP  +  P  P+    E G   P    RG PG    +  
Sbjct: 901  TQGPPGATGFPGSAGR-VGPPGPAGAPGPAGPL---GEPGKEGPPGL-RGDPGSHGRVGD 955

Query: 688  PGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGW------- 740
             G  GP   PG    P   G+   D             RG   + G+R  RG        
Sbjct: 956  RGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTG--QRGIVGMPGQRGERGMPGLPGPA 1013

Query: 741  -TFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPR----LRGRATAVAPRPLPAAP 795
             T       GA  ++ P  P   P       E   E P       GR  AV  R     P
Sbjct: 1014 GTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDP 1073

Query: 796  GFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAP-RAG 837
            G +GL   Q  P     +G P   G  G PG R     P RAG
Sbjct: 1074 GPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAG 1116



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 60/211 (28%), Positives = 72/211 (34%), Gaps = 28/211 (13%)

Query: 636 TLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP--------ERGSPGRPAFLRS 687
           T G G+   G G +G +      PVV G   G   P  P        ERG  GRP     
Sbjct: 99  TPGGGNTNFGRGRKGQKGEPGLVPVVTGIR-GRPGPAGPPGSQGPRGERGPKGRPGPRGP 157

Query: 688 PGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALR 747
            G+ G   VPG    P P G  +      D   R F    +  +AG   + G      L 
Sbjct: 158 QGIDGEPGVPGQPGAPGPPGHPS--HPGPDGLSRPF----SAQMAGLDEKSGLGSQVGLM 211

Query: 748 KGAPREQPPASPAASPCQ----APRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVL 803
            G+     P  P     Q     P  P  E   P   G   +  P   P  PG  G    
Sbjct: 212 PGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDG---- 267

Query: 804 QPFPARSRGLGVPSQQGPTGSPGCRDRASAP 834
              P R+   G P + G  GSPG R    AP
Sbjct: 268 --EPGRN---GNPGEVGFAGSPGARGFPGAP 293



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 108/425 (25%), Positives = 143/425 (33%), Gaps = 95/425 (22%)

Query: 444 AGETTPLGEARGPCWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLRRGR 503
           A   TP GE    C +  G   +   RGR G+             +G  G  P  +   R
Sbjct: 83  ADPVTPPGECCPVCSQTPGGGNTNFGRGRKGQ-------------KGEPGLVPV-VTGIR 128

Query: 504 GMPGRVGNGVGEG-RGASEPEGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQV 562
           G PG  G    +G RG   P+G P PR          G + +   P +  + G   PG  
Sbjct: 129 GRPGPAGPPGSQGPRGERGPKGRPGPR----------GPQGIDGEPGVPGQPGA--PGPP 176

Query: 563 AHGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVR 622
            H            + PG    G+ R  +   AQ+ G               ++G     
Sbjct: 177 GH-----------PSHPG--PDGLSRPFS---AQMAGL------------DEKSG----- 203

Query: 623 EIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRP 682
                   L +   L PGS G  +G +GP+        + G + G A P  P  G PG P
Sbjct: 204 --------LGSQVGLMPGSVGP-VGPRGPQG-------LQGQQGG-AGPTGPP-GEPGDP 245

Query: 683 AFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLAD----RAFPVRGAGPIAGRRRRR 738
             +   G  GP   PG        GR  G+  E   A     R FP  GA  + G +  R
Sbjct: 246 GPMGPIGSRGPEGPPGKPGEDGEPGRN-GNPGEVGFAGSPGARGFP--GAPGLPGLKGHR 302

Query: 739 GWTFAAALRK--GAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPG 796
           G       +   GAP  +  A P          P      P  RGR   + P+    APG
Sbjct: 303 GHKGLEGPKGEVGAPGSKGEAGPTGP--MGAMGPLGPRGMPGERGR---LGPQ---GAPG 354

Query: 797 FSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPP 856
             G   +   P     LG+P   G  G+PG +  A    A    G        G   P  
Sbjct: 355 QRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVG 414

Query: 857 SPRAP 861
           SP  P
Sbjct: 415 SPGLP 419



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 118/432 (27%), Positives = 131/432 (30%), Gaps = 103/432 (23%)

Query: 471  GRPGRVAGASGRRGASQARGGTGRAPARLRRG----RGMPGRVG----NGVGEGRGASEP 522
            G PG   G  G +G     G  G    R  RG    RG PG  G     G+  G G   P
Sbjct: 684  GPPGE-GGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGP 742

Query: 523  EGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLA 582
            +G P P           G   LQ +P   ER     PG        R G+    A  G A
Sbjct: 743  KGSPGPSGTPG----DTGPPGLQGMP--GERGIAGTPGPKGD----RGGIGEKGAE-GTA 791

Query: 583  GSGVQRALA--LAAAQLGGWTTCVVSPNLRR-----GSRRAGNHRVREIEFGSALLAALN 635
            G+   R L   L      G T     P  R      GSR  GN   R             
Sbjct: 792  GNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSR--GNPGSR------------G 837

Query: 636  TLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP----ERGSPGRPAFLRSPGLC 691
              GP       G QGP       P V G       P  P    + GSPG      SPG  
Sbjct: 838  ENGPTGAVGFAGPQGPDGQ----PGVKGE------PGEPGQKGDAGSPGPQGLAGSPGPH 887

Query: 692  GPGPVPGGLSVPTPCGRGA-GDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGA 750
            GP  VPG        GRG  G          A  V   GP                  GA
Sbjct: 888  GPNGVPG-----LKGGRGTQGPPGATGFPGSAGRVGPPGP-----------------AGA 925

Query: 751  PREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQ------ 804
            P    PA P   P      P      P   GR     P   P  PG  G           
Sbjct: 926  P---GPAGPLGEP--GKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPD 980

Query: 805  --PFPARSRG----LGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPP--- 855
              P PA + G    +G+P Q+G  G PG    A  P      G+       G + PP   
Sbjct: 981  GPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSN 1040

Query: 856  -----PSPRAPA 862
                 P P  PA
Sbjct: 1041 GPVGEPGPEGPA 1052



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 112/438 (25%), Positives = 141/438 (32%), Gaps = 83/438 (18%)

Query: 444  AGETTPLGEARGPCWK-ARGAVPSGRLRGRPGRV-----AGASGRRGASQARGGTGRAPA 497
            AG   P G+  G   K A G   +   RG PG +     AG +G +G    RG  G   +
Sbjct: 770  AGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGS 829

Query: 498  RLRRG-RGMPGRVGNGVGEGRGASEPEGEP-------EPRARADLEVLQAGFERLQSL-- 547
            R   G RG  G  G  VG   G   P+G+P       EP  + D     AG    Q L  
Sbjct: 830  RGNPGSRGENGPTG-AVGFA-GPQGPDGQPGVKGEPGEPGQKGD-----AGSPGPQGLAG 882

Query: 548  ---PELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCV 604
               P     + G   G+   G     G   +A R G  G       A    + G      
Sbjct: 883  SPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGK----- 937

Query: 605  VSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQG-------PRSSTPE 657
              P   RG    G+H              +   GP     G G +G       P    P 
Sbjct: 938  EGPPGLRGD--PGSH------------GRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPP 983

Query: 658  CPVVNGSEWGLAAPLSP--ERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFS- 714
             P     + G+        ERG PG P    +PG  GP    G    P P G    +   
Sbjct: 984  GPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPV 1043

Query: 715  -----EADLADRAFPVRGAGPIAGRRRRRGWTFAAAL--RKGAPREQPPAS--------- 758
                 E    +   P R      G R  RG    A L   +GAP    P           
Sbjct: 1044 GEPGPEGPAGNDGTPGRDGA--VGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRG 1101

Query: 759  ------PAASPCQAPRAPEKETEAPRL-RGRATAVAPRPLPAAPGFSGLCVLQ--PFPAR 809
                  P   P +A +      + PR  +G       R      GF+GL  L   P P  
Sbjct: 1102 DPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNG 1161

Query: 810  SRG-LGVPSQQGPTGSPG 826
             +G  G+P   GP G PG
Sbjct: 1162 EQGSAGIPGPFGPRGPPG 1179



 Score = 38.9 bits (89), Expect = 0.021
 Identities = 108/429 (25%), Positives = 130/429 (30%), Gaps = 76/429 (17%)

Query: 426  AVGLAG--GIEAAVLLRGARAGETTPLGEAR--GPCWKARGAVPSGRLRGRPGRVAGASG 481
            AVG AG  G +    ++G   GE    G+A   GP   A    P G     P  V G  G
Sbjct: 844  AVGFAGPQGPDGQPGVKG-EPGEPGQKGDAGSPGPQGLAGSPGPHG-----PNGVPGLKG 897

Query: 482  RRGASQARGGTGRAPARLRRGRGMPGRVGN-GVGEGRGASEPEGEPEPRARADLEVLQAG 540
             RG     G TG          G  GRVG  G     G + P GEP           + G
Sbjct: 898  GRGTQGPPGATGFP--------GSAGRVGPPGPAGAPGPAGPLGEPG----------KEG 939

Query: 541  FERLQSLPELAERLGGRCP-----GQVAHGVLARAGLLAAAARPGLAGSGVQRALALAAA 595
               L+  P    R+G R P     G    G     G       PG AG+  QR +     
Sbjct: 940  PPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPG 999

Query: 596  QLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSST 655
            Q G            RG            + G     A    GP       G+ GP    
Sbjct: 1000 QRG-----------ERGMPGLPGPAGTPGKVGPT--GATGDKGPPGPVGPPGSNGPVGEP 1046

Query: 656  -PECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFS 714
             PE P  N    G    +  ERG  G P     PG  G    PG +  P   G+     S
Sbjct: 1047 GPEGPAGNDGTPGRDGAVG-ERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGS 1105

Query: 715  EADLAD------RAFPV----------RGAGPIAGRRRRRGWTFAAALRKGAPREQPPAS 758
               +        R  P            G     G++  RG+T    L  G P       
Sbjct: 1106 RGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGL-PGPPGPNGEQG 1164

Query: 759  PAASPCQ-APRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPS 817
             A  P    PR P          G    + P   P   G  G          +   G P 
Sbjct: 1165 SAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVG---------EAGPEGPPG 1215

Query: 818  QQGPTGSPG 826
            + GP G PG
Sbjct: 1216 EPGPPGPPG 1224


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 119/455 (26%), Positives = 149/455 (32%), Gaps = 73/455 (16%)

Query: 430  AGGIEAAVLLRGARA--GETTPLGEARGPCWK-ARGAV--PSGRLRGRPGRVAGASGRRG 484
            A G+     L G R   G T   G    P  K A G V  P   + G PGR     G++G
Sbjct: 798  APGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGR----DGQQG 853

Query: 485  ASQARGGTGRAPARLRRGR---------------GMPGRVGNGVGEG--RGASEPEGEPE 527
             +  RG  G    R  +G                GMPG  G  +G     G   P G P 
Sbjct: 854  QTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPG 913

Query: 528  PRARADLEVLQA--GFERLQSLPELAERLG-------------GRC-PGQVAH-GVLARA 570
            P     +  LQ   G   L   P L   LG             G C  GQ AH G L   
Sbjct: 914  PPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEK 973

Query: 571  GLLAAAARPGLAGS--------GVQRALALAAA--QLGGWTTCVVSPNLRRGSRRAGNHR 620
            G       PG+ G          ++R  A  A      G   CV SP L       G   
Sbjct: 974  GEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRG 1033

Query: 621  VREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPG 680
                            +GP  F   +G+ G        P + G E GL   L+ ++G PG
Sbjct: 1034 EEGPPGMRGSPGPPGPIGPPGFPGAVGSPG-------LPGLQG-ERGLTG-LTGDKGEPG 1084

Query: 681  RPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGW 740
             P     PG  GP  +PG        G  AG+  E             GP AG R  RG 
Sbjct: 1085 PPGQPGYPGATGPPGLPGIKGERGYTG-SAGEKGEPGPPGSEGLPGPPGP-AGPRGERGP 1142

Query: 741  TFAAALR-----KGAPREQPPASPAASPCQA----PRAPEKETEAPRLRGRATAVAPRPL 791
               +  +     +G P    P  P   P +     P  P+ E  +  +RG +        
Sbjct: 1143 QGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGP 1202

Query: 792  PAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPG 826
            P  PG  G   L     +    G+    GP G PG
Sbjct: 1203 PGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPG 1237



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 105/435 (24%), Positives = 136/435 (31%), Gaps = 77/435 (17%)

Query: 471  GRPGRVAGASGRRGASQARGGTGRAPARLRRGRG-------------MPGRVGNGVGEGR 517
            G PG   G +GR G S   G  G A  +  +G G             M GR G    +G 
Sbjct: 691  GDPG-TPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGE 749

Query: 518  GASEPEGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAA 577
               E  G P           Q G   +Q  P L    G   PG    GV    G   A  
Sbjct: 750  QGPEGVGRPGKPG-------QPGLPGVQGPPGLKGVQGE--PGPPGRGVQGPQGEPGAPG 800

Query: 578  RPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTL 637
             PG+ G    R       + G       SP ++  +   G         G+++       
Sbjct: 801  LPGIQGLPGPRGPPGPTGEKGAQG----SPGVKGATGPVGPP-------GASVSGP---- 845

Query: 638  GPGSFG----AGL----GAQGPRSSTPE-----CP-----VVNGSE-----WGLAAPLSP 674
             PG  G     GL    G +GPR    E     CP     + +G       W  ++    
Sbjct: 846  -PGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPG 904

Query: 675  ERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGR 734
             +G PG P     PG+ G   VPG   +P   G  A +     +            + G+
Sbjct: 905  PQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTA-ELGSLPIEQHLLKSICGDCVQGQ 963

Query: 735  RRRRGWTFAAALRKGAPREQP-PASPAASPC-------QAPRAPEKETEAPRLRGRATAV 786
            R   G+     + KG   +Q  P  P    C       + PRA  +E       G    V
Sbjct: 964  RAHPGYL----VEKGEKGDQGIPGVPGLDNCAQCFLSLERPRA--EEARGDNSEGDPGCV 1017

Query: 787  APRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETF 846
                LP  PG  G    +  P      G P   GP G PG       P    E G     
Sbjct: 1018 GSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLT 1077

Query: 847  LRNGGLYPPPSPRAP 861
               G   PP  P  P
Sbjct: 1078 GDKGEPGPPGQPGYP 1092



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 98/405 (24%), Positives = 135/405 (33%), Gaps = 55/405 (13%)

Query: 471 GRPGRVAGASGRRGASQARG--GTGRAPAR--LRRGRGMPGRVGNGVGEG-------RGA 519
           G PG   G  G +G+S   G  G G  P +  ++  +G P  V   + EG        G 
Sbjct: 467 GDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGK 526

Query: 520 SEPEGEP-EP-RARADLEVLQAGFERLQSLPELAERLGGR-------CPGQVAHGVLARA 570
             P+GEP +P  AR D  +     E+ +     +  +G +         G V        
Sbjct: 527 PGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLP 586

Query: 571 GLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNH---RVREIEFG 627
           GL   A  PGL G       A  A   G      V P   +G++         +  ++ G
Sbjct: 587 GLPGRAGVPGLKGEKGNFGEAGPAGSPG--PPGPVGPAGIKGAKGEPCEPCPALSNLQDG 644

Query: 628 SALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRS 687
              + AL    PG  G   G  GP             E GL      ++G  G P    +
Sbjct: 645 DVRVVAL----PGPSGEK-GEPGPPGFGLPGKQGKAGERGLKG----QKGDAGNPGDPGT 695

Query: 688 PGLCGPGPVPGGLSVPTPCG----RGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFA 743
           PG  G   + G   V  P G    +G G  +   L      + G     G +  +G    
Sbjct: 696 PGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQG---- 751

Query: 744 AALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVL 803
               +G  R   P  P     Q P   +     P   GR     P+  P APG  G+  L
Sbjct: 752 ---PEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQ-GPQGEPGAPGLPGIQGL 807

Query: 804 -----QPFPARSRGL----GVPSQQGPTGSPGCRDRASAPRAGAE 839
                 P P   +G     GV    GP G PG        R G +
Sbjct: 808 PGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQ 852



 Score = 37.7 bits (86), Expect = 0.047
 Identities = 102/402 (25%), Positives = 127/402 (31%), Gaps = 94/402 (23%)

Query: 469  LRGRPGRVAGASGRRGASQARGGTGRAPARLRRGR----GMPGRVGNGVGEGR-GASEPE 523
            LRG PG  AG  G  G    +G TG       +G     G PG  G    EG  GA  P+
Sbjct: 1226 LRGDPGP-AGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQ 1284

Query: 524  GEPEPRARADLEVL--QAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGL 581
            G P P           Q G   + ++    +R         A G    AGL      PG 
Sbjct: 1285 GRPGPPGHVGPPGPPGQPGPAGISAVGLKGDR--------GATGERGLAGLPGQPGPPGH 1336

Query: 582  AGSGVQRALALAAAQLGG-WTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPG 640
             G   +     AA + G         P   +G   A   + +  E G A +      GPG
Sbjct: 1337 PGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPG----GPG 1392

Query: 641  SFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGL 700
              G+ +G  GP                     + ERG PG P    SPGL G   VPG +
Sbjct: 1393 KSGS-MGPVGPPGP------------------AGERGHPGAPGPSGSPGLPG---VPGSM 1430

Query: 701  SVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPA 760
                      GD    D   R             R+     F   +     R Q P   A
Sbjct: 1431 ----------GDMVNYDEIKRFI-----------RQEIIKMFDERMAYYTSRMQFPMEMA 1469

Query: 761  ASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQG 820
            A+P + P  P K+    R             P APG  GL               P Q G
Sbjct: 1470 AAPGR-PGPPGKDGAPGR-------------PGAPGSPGL---------------PGQIG 1500

Query: 821  PTGSPGCRDRASAPRAGAEAGSMETFLR-NGGLYPPPSPRAP 861
              G  G       P    E G +   +    GL  PP P+ P
Sbjct: 1501 REGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGP 1542



 Score = 37.0 bits (84), Expect = 0.079
 Identities = 104/438 (23%), Positives = 131/438 (29%), Gaps = 88/438 (20%)

Query: 462  GAVPSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLRRGRGMPGRVGNGVGEG----- 516
            G V S  L G PG + G  G  G    RG  G  P       G PG VG+    G     
Sbjct: 1015 GCVGSPGLPGPPG-LPGQRGEEGPPGMRGSPG--PPGPIGPPGFPGAVGSPGLPGLQGER 1071

Query: 517  --RGASEPEGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLA 574
               G +  +GEP P         Q G+      P L              G+    G   
Sbjct: 1072 GLTGLTGDKGEPGPPG-------QPGYPGATGPPGLP-------------GIKGERGYTG 1111

Query: 575  AAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAAL 634
            +A   G  G      L       G        P   RG +  GN   +  +         
Sbjct: 1112 SAGEKGEPGPPGSEGLPGPPGPAG--------PRGERGPQ--GNSGEKGDQGFQGQPGFP 1161

Query: 635  NTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAP--LSPERGSPGRPAFLRSPGLCG 692
               GP  F   +G+ GP     E     GSE G+  P  L    G PG P      GL G
Sbjct: 1162 GPPGPPGFPGKVGSPGPPGPQAE----KGSE-GIRGPSGLPGSPGPPGPPGIQGPAGLDG 1216

Query: 693  -------------PGPV--PGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRR 737
                         PGP   PG +  P   G+           D   P  G     GR   
Sbjct: 1217 LDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKP--GPPGSTGRPGA 1274

Query: 738  RGWTFAAALR-----------KGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAV 786
             G   A   +            G P +  PA  +A   +  R    E     L G+    
Sbjct: 1275 EGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPP 1334

Query: 787  APRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGC------RDRASAPRAGAEA 840
                 P  PG  G    +  P +    G P  +G  G+ G       + RA  P    ++
Sbjct: 1335 GHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKS 1394

Query: 841  GSMETFLRNGGLYPPPSP 858
            GSM       G   PP P
Sbjct: 1395 GSM-------GPVGPPGP 1405



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 114/459 (24%), Positives = 151/459 (32%), Gaps = 83/459 (18%)

Query: 440 RGARAGETTPLGEARGPCWKARGA----VPSGRLRGRPGR-VAGASGRRGASQARGGTG- 493
           RGA+  + T   E       AR +     PSG   G+  R + G  G +G   ARG    
Sbjct: 303 RGAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGNDCV 362

Query: 494 --RAPARLRRGRGMPGRVGNGVGEGRGASEPEGEPEPRARADL--EVLQAGFERLQSLPE 549
                A L+   G  G  G       GA  P G P          E    G + +   P 
Sbjct: 363 RISPDAPLQCAEGPKGEKGES-----GALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPG 417

Query: 550 LAERLGGRC----PGQVAH-GVLARAGLLAAAARPGLAGS-GVQRALALAAAQLGGWTTC 603
              R G  C     GQ    G +   GL      PGL G  G+   L       GG    
Sbjct: 418 RDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGI--GLPGTPGDPGG---- 471

Query: 604 VVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPE-CPVV- 661
              P   +G + +     +E              GPG      G +G +    E CP + 
Sbjct: 472 ---PPGPKGDKGSSGIPGKE--------------GPGGKPGKPGVKGEKGDPCEVCPTLP 514

Query: 662 NGSEWGLAAPLSP-ERGSPGRPAFLRS-PGLCGPGPVPGG--LSVPTPCGR--------G 709
            G +  +  P  P  +G PG P   R  PG+ G     G   LS  +  G          
Sbjct: 515 EGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGA 574

Query: 710 AGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAA------SP 763
           +GD           P R   P  G +  +G  F  A   G+P    P  PA        P
Sbjct: 575 SGDVGSPGFGLPGLPGRAGVP--GLKGEKG-NFGEAGPAGSPGPPGPVGPAGIKGAKGEP 631

Query: 764 CQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTG 823
           C+   A     +     G    VA   LP   G  G    +P P    G G+P +QG  G
Sbjct: 632 CEPCPALSNLQD-----GDVRVVA---LPGPSGEKG----EPGPP---GFGLPGKQGKAG 676

Query: 824 SPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAPA 862
             G + +        + G+  T  R  GL   P  + PA
Sbjct: 677 ERGLKGQKGDAGNPGDPGTPGTTGR-PGLSGEPGVQGPA 714


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 53/152 (34%), Positives = 56/152 (36%), Gaps = 21/152 (13%)

Query: 711 GDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAP 770
           G  S  + A    P RGA P A  R  RG   AAA         PP +PA  P  AP A 
Sbjct: 89  GSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAA------PPPTPAPPPPPAPVAA 142

Query: 771 EKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDR 830
                APR    A    P P PA PG        P   R+  L  P    P   P     
Sbjct: 143 AAPARAPRAAAAAATAPPSPGPAQPG--------PRAQRAAPLAAP-PPAPAAPP----- 188

Query: 831 ASAPRAG-AEAGSMETFLRNGGLYPPPSPRAP 861
           A AP AG   A       R   L PPP P AP
Sbjct: 189 AVAPPAGPRRAPPPAVAAREPPLPPPPQPPAP 220



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 36/127 (28%), Positives = 45/127 (35%), Gaps = 12/127 (9%)

Query: 669 AAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGA 728
           A P +P R   G PA   +     P P P     P P    A   +    A  A      
Sbjct: 106 ATPPAPPRAPRGAPA---AAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSP 162

Query: 729 GPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAP 788
           GP     R +         + AP   PP +PAA P  AP A  +    P +  R   + P
Sbjct: 163 GPAQPGPRAQ---------RAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPP 213

Query: 789 RPLPAAP 795
            P P AP
Sbjct: 214 PPQPPAP 220


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 110/418 (26%), Positives = 141/418 (33%), Gaps = 75/418 (17%)

Query: 471 GRPGRVAGASGRRGASQARGGTGRAPARLRRGR----GMPGRVGNGVGEGR-GASEPEGE 525
           G PG+  GASG  G   A+G    +  +  +G     G PG  G     GR G +  +G+
Sbjct: 539 GLPGK-HGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGD 597

Query: 526 PEPRA-RADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAGS 584
           P P     D      GF      P  A  +G   PG    G     G       PG+ G 
Sbjct: 598 PGPPGDHEDATPGGKGFPGPLGPPGKAGPVGP--PGLGFPGPPGERGHPGVPGHPGVRGP 655

Query: 585 GVQRALALAAAQLGGWTTCVVS---------------------PNLRRGSRRAGNHRVRE 623
              +       Q G   +C V+                     P    G   +  H+ R 
Sbjct: 656 DGLKG------QKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRP 709

Query: 624 IEFGSALLAA----LNTLGPGSFGAGLGAQ--GPRSSTPECPVVNGSEWGLAAPLSPERG 677
              G+A +         +G   FG   G+   GP    P  P VNG +     P     G
Sbjct: 710 GTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGP-PGPPGSPGVNGQKGIPGDPAFGHLG 768

Query: 678 SPGRPAFLRSPGLCGP----------GP--VPGGLSVPTPCGR-GAGDFSEADLADRAFP 724
            PG+      PG+ GP          GP  +PG L +  P GR G   F           
Sbjct: 769 PPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSC 828

Query: 725 VRGAGPIAGRRRRRGWTFA--AALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGR 782
            RGA  I G+    G+  +  A   KG P +  P  PA                P L GR
Sbjct: 829 ERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMK-----------GLPGLPGR 877

Query: 783 ATAVAPRPLPAAPGFSGLCVL--QPFPARSRGL----GVPSQQGPTGSPGCRDRASAP 834
             A  P  LP  PG  G   L   P P   RGL    G P ++G  G+ GC      P
Sbjct: 878 PGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEP 935



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 125/480 (26%), Positives = 155/480 (32%), Gaps = 70/480 (14%)

Query: 417  DLALQQILEAVGLAGGI-EAAVLLRGARAGETTPLGEARGPCWKARGAVPS--GRLRGRP 473
            D  L+    A+G  G   E A++ +    GE  P G+   P  +     P   GR RG P
Sbjct: 946  DRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGR-RGEP 1004

Query: 474  GRVA------GASGRRGASQARGGTGRAPARLRRG----RGMPGRVGNGVGEGR-GASEP 522
            GR        G  G +G     G  G   +   RG     G+PG  G     G  G S  
Sbjct: 1005 GRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGI 1064

Query: 523  EGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQV-AHGVLARAGLLAAAARPGL 581
            +G   P+          G    +  P         CPG   A G     G+      PG 
Sbjct: 1065 DGARGPKGNKGDPASHFGPPGPKGEPG-----SPGCPGHFGASGEQGLPGIQGPRGSPGR 1119

Query: 582  AGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGP-G 640
             G              G        P LR      G+   R ++    +       GP G
Sbjct: 1120 PGPPGSSGPPGCPGDHG-------MPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSG 1172

Query: 641  SFGA----GL-------GAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPG 689
            S G     GL       GA G     P  PV      G+   L  ERG PG P  +  PG
Sbjct: 1173 SPGLNGLHGLKGQKGTKGASGLHDVGPPGPV------GIPG-LKGERGDPGSPG-ISPPG 1224

Query: 690  LCG----PGPVPGGLSVPTPCG---RGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTF 742
              G    PGP PG    P P G   R   D  +        P    GP  G     G   
Sbjct: 1225 PRGKKGPPGP-PGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGP-RGAPGPPGLPG 1282

Query: 743  AAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCV 802
            +  L +G P +     P   P   P  P      P   G+     P   P   G  G   
Sbjct: 1283 SVDLLRGEPGDCGLPGPPGPP--GPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGF-- 1338

Query: 803  LQPFPARSRGL-GVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAP 861
              P P   +GL G P ++GPTG PG R     P        ++   R  GL   P  R P
Sbjct: 1339 --PGPPGEKGLPGPPGRKGPTGLPGPRGEPGPP------ADVDDCPRIPGLPGAPGMRGP 1390



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 104/411 (25%), Positives = 132/411 (32%), Gaps = 66/411 (16%)

Query: 470  RGRPGRVA--GASGRRGASQARGGTGRAPARLRRGRGMPGRVGN-GVGEGRGASEPEGEP 526
            +GR G     G  G  G S  RG  G     +    G+PG  G+ G   G+G     G P
Sbjct: 809  KGREGHAGFPGVPGPPGHSCERGAPG-----IPGQPGLPGYPGSPGAPGGKGQPGDVGPP 863

Query: 527  EPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAGSGV 586
             P          AG + L  LP       GR PG  AHG     G+       GL G   
Sbjct: 864  GP----------AGMKGLPGLP-------GR-PG--AHGPPGLPGIPGPFGDDGLPGPPG 903

Query: 587  QRALALAAAQLGGWTTCVVSPNL--RRGSRRAGNHRVREIEFGSALLAALNTLGPGSFG- 643
             +        L G+      P     RG   A      + E G   ++ L    PG  G 
Sbjct: 904  PKG----PRGLPGF------PGFPGERGKPGAEGCPGAKGEPGEKGMSGL----PGDRGL 949

Query: 644  -AGLGAQGPRSSTPECPVVNGSEWGLAAPLSP--ERGSPGRPAFLRSPGLCGPGPVPGGL 700
                GA GP     E  ++  S+ G      P  + G PG      +PG+ G    PG  
Sbjct: 950  RGAKGAIGPPGDEGEMAII--SQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRY 1007

Query: 701  SVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPA 760
              P   G   G+  E     +  P    GP  G    RG+     L         P  P 
Sbjct: 1008 GPP---GFHRGEPGEKG---QPGPPGPPGP-PGSTGLRGFIGFPGLPGDQGEPGSPGPPG 1060

Query: 761  ASPCQAPRAPEKETEAPRLRGRATAVAPRP-LPAAPGFSGLCVLQPFPARSRGLGVPSQQ 819
             S     R P+     P            P  P  PG  G    Q  P      G P + 
Sbjct: 1061 FSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRP 1120

Query: 820  GPTGS---PGCRDRASAPRAGAEAGSM-----ETFLRNGGLYPPPSPRAPA 862
            GP GS   PGC      P    + G M          + G+  PP  + P+
Sbjct: 1121 GPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPS 1171



 Score = 38.9 bits (89), Expect = 0.021
 Identities = 120/492 (24%), Positives = 164/492 (33%), Gaps = 123/492 (25%)

Query: 389 CDFKTEPPALIQAPWGVHPGQHLPLQLIDLALQQILEA----VGLAGGIEAAVLLRGARA 444
           C F+    +L   PW         L LI  ++Q +  +    +G  GG + +V       
Sbjct: 11  CSFRLTK-SLATGPWS--------LILILFSVQYVYGSGKKYIGPCGGRDCSVC------ 55

Query: 445 GETTPLGEARGPCWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLRRG-R 503
               P   +RGP        P G L G PG + G SG +G    RG  G A  +  +G  
Sbjct: 56  -HCVPEKGSRGPPGPPGPQGPIGPL-GAPGPI-GLSGEKGMRGDRGPPGAAGDKGDKGPT 112

Query: 504 GMPGRVG-NGVGEGRGASEPEGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQV 562
           G+PG  G +G+    G   P G+P            +G    +  P      GGR     
Sbjct: 113 GVPGFPGLDGIPGHPGPPGPRGKPG----------MSGHNGSRGDPGFP---GGR----- 154

Query: 563 AHGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVR 622
             G L   G L      G  G+ V    A+   Q               G R        
Sbjct: 155 --GALGPGGPLGHPGEKGEKGNSVFILGAVKGIQ---------------GDR-------- 189

Query: 623 EIEFGSALLAALNTLGPGSFGAGLGAQGPRS-----------STPECPVVNGSEW-GLAA 670
               G   L  L    PGS+GAG G  GP               P  P + G+   G+  
Sbjct: 190 ----GDPGLPGL----PGSWGAG-GPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKG 240

Query: 671 PLSP-----ERGSPGRPAFLRSPGLC------GPGPVPGGLSVPTPCGRG--AGDFSEAD 717
            +       ++GSPG    +  P  C      G   +PG + +P P GR   +G  ++ +
Sbjct: 241 QMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGE 300

Query: 718 LADRAFPVRGAGP-------IAGRRRRRGWT-----FAAALRKGAP--REQP-PASPAAS 762
                FP     P         G +   G       F     KG P  R  P P     +
Sbjct: 301 KGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVT 360

Query: 763 PCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPT 822
           P    + P  +   P   G    V P   P  PG  G    +P  A +  +G P  QG  
Sbjct: 361 PPLPLKGPPGDPGFPGRYGETGDVGP---PGPPGLLG----RPGEACAGMIGPPGPQGFP 413

Query: 823 GSPGCRDRASAP 834
           G PG    A  P
Sbjct: 414 GLPGLPGEAGIP 425



 Score = 37.0 bits (84), Expect = 0.079
 Identities = 25/59 (42%), Positives = 28/59 (47%), Gaps = 9/59 (15%)

Query: 21  PGEKGEKRRTKQIIAAQAGGEGGRAQPGLPCSVDLATGLEGP--LGGPAVDLDVGFSPG 77
           PGEKGEK  +  I+ A  G +G R  PGLP       GL G    GGPA        PG
Sbjct: 166 PGEKGEKGNSVFILGAVKGIQGDRGDPGLP-------GLPGSWGAGGPAGPTGYPGEPG 217



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 98/373 (26%), Positives = 122/373 (32%), Gaps = 59/373 (15%)

Query: 470 RGRPGRVAGASGRRGASQARGGTGR-APARLRRGRGMPGRVGNGVGEGRGASEPEGEPEP 528
           RG PG + G  G  GA    G TG      L    G PGR G     G G     G+P  
Sbjct: 189 RGDPG-LPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPG- 246

Query: 529 RARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAG-SGVQ 587
                 EV Q G       P L       C  +   G+    G++     PG  G SG+ 
Sbjct: 247 ------EVGQQGSPG----PTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIG 296

Query: 588 RALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGS----ALLAALNTLG-PGSF 642
              A     + G+      P    GS            +GS     L   L  +G PG F
Sbjct: 297 ---AKGEKGIPGFP----GPRGDPGS------------YGSPGFPGLKGELGLVGDPGLF 337

Query: 643 GAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCG----PGPVPG 698
           G  +G +G   +        G    L  P  P +G PG P F    G  G    PGP PG
Sbjct: 338 GL-IGPKGDPGNRGH----PGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGP-PG 391

Query: 699 GLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQP-PA 757
            L  P     G           + FP  G   + G     G   +A  + G P     P 
Sbjct: 392 LLGRPGEACAG----MIGPPGPQGFP--GLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPG 445

Query: 758 SPAASPCQAPRAPEKETEAPRLRGRATAVAP---RPLPAAPGFSGLCVLQPFPARSRG-L 813
           +P                 P  +G    V P   R      G  GLC  +P P    G  
Sbjct: 446 APGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPP 505

Query: 814 GVPSQQGPTGSPG 826
           G+P +QG  G  G
Sbjct: 506 GLPGRQGSKGDLG 518



 Score = 30.8 bits (68), Expect = 5.7
 Identities = 58/210 (27%), Positives = 70/210 (33%), Gaps = 41/210 (19%)

Query: 639 PGSFGAGLGAQG-PRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVP 697
           PG  GA  G QG P SS   C V N    G+   + P  G  G      + GLC   P P
Sbjct: 441 PGLPGAP-GLQGLPGSSVIYCSVGNPGPQGIKGKVGPP-GGRGPKGEKGNEGLCACEPGP 498

Query: 698 GGLSVPTPCGRGAGDFSEADLA---------DRAFP----------VRGAGPIAGRRRRR 738
            G   P P G      S+ DL          D   P            GA    G +  +
Sbjct: 499 MG--PPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAK 556

Query: 739 GWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFS 798
           G    + + KG   E+ P  P   P Q           P   GR      +  P  PG  
Sbjct: 557 GDMVVSRV-KGHKGERGPDGPPGFPGQ-----------PGSHGRDGHAGEKGDPGPPGDH 604

Query: 799 GLCVL--QPFPARSRGLGVPSQQGPTGSPG 826
                  + FP     LG P + GP G PG
Sbjct: 605 EDATPGGKGFPGP---LGPPGKAGPVGPPG 631



 Score = 30.4 bits (67), Expect = 7.4
 Identities = 53/195 (27%), Positives = 61/195 (31%), Gaps = 28/195 (14%)

Query: 674 PERGSPGRPAFLRSPGLCGP-GPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIA 732
           PE+GS G       PG  GP GP+ G L  P P G         D        RG    A
Sbjct: 59  PEKGSRG------PPGPPGPQGPI-GPLGAPGPIGLSGEKGMRGD--------RGPPGAA 103

Query: 733 GRRRRRGWTFAAAL--RKGAPREQPPASPAASP-CQAPRAPEKETEAPRLRGRATAVAPR 789
           G +  +G T         G P    P  P   P          +   P  RG      P 
Sbjct: 104 GDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPL 163

Query: 790 PLPAAPGFSGLCVLQPFPARSRGLG-VPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLR 848
             P   G  G  V          LG V   QG  G PG      +  AG  AG       
Sbjct: 164 GHPGEKGEKGNSVFI--------LGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGE 215

Query: 849 NGGLYPPPSPRAPAV 863
            G + PP  P  P +
Sbjct: 216 PGLVGPPGQPGRPGL 230



 Score = 30.4 bits (67), Expect = 7.4
 Identities = 34/132 (25%), Positives = 42/132 (31%), Gaps = 7/132 (5%)

Query: 638  GPGSFGAGLGAQGPRSSTPECPVVNGSEW--GLAAPLS----PERGSPGRPAFLRSPGLC 691
            GP       G  GP +   +CP + G     G+  P      P    P  P     PGL 
Sbjct: 1355 GPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLD 1414

Query: 692  GPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAP 751
            G   V G    P P GR  GD  E        P    G    +    G+     L   + 
Sbjct: 1415 GRRGVDGVPGSPGPPGR-KGDTGEDGYPGGPGPPGPIGDPGPKGFGPGYLGGFLLVLHSQ 1473

Query: 752  REQPPASPAASP 763
             +Q P  P   P
Sbjct: 1474 TDQEPTCPLGMP 1485


>gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [Homo
           sapiens]
          Length = 828

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 107/400 (26%), Positives = 131/400 (32%), Gaps = 68/400 (17%)

Query: 452 EARGPCWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLRRGR-GMPGRVG 510
           EA G C+K       G         +G  G RG   A+G  G      ++GR G PG  G
Sbjct: 241 EAYGECYKVSCLEIPGP--------SGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEG 292

Query: 511 NGVGEGRGASEPEGEPEPRARADL--EVLQAGFERLQSLPELAERLGGRCPGQVAHGVLA 568
                      P G P P+       E  + G +  +  P LA + G    GQ   G L 
Sbjct: 293 -----------PIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNG--TDGQ--KGKLG 337

Query: 569 RAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGS 628
           R G       PG  G               G+     SP   RG +       R    G 
Sbjct: 338 RIGPPGCKGDPGNRGPD-------------GYPGEAGSPG-ERGDQGGKGDPGRPGRRGP 383

Query: 629 ALLAALNTLGPGSFGA--GLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGR---PA 683
                     PG  GA    G QG  S  P  P V G++ G   P  P +G PGR   P 
Sbjct: 384 ----------PGEIGAKGSKGYQG-NSGAPGSPGVKGAKGG-PGPRGP-KGEPGRRGDPG 430

Query: 684 FLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFP-VRGAGPIAGRRRRRGWTF 742
              SPG  GP    G      P G      ++    DR  P  RG     G   ++G   
Sbjct: 431 TKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQG--- 487

Query: 743 AAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAP-GFSGLC 801
                +G P +  P   +  P             P  RG A      P P  P G  G  
Sbjct: 488 ----SRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRG-APGEKGEPGPRGPEGGRGDF 542

Query: 802 VLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAG 841
            L+  P R    G P+  GP G PG R     P    E G
Sbjct: 543 GLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPG 582



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 30/90 (33%), Positives = 35/90 (38%), Gaps = 12/90 (13%)

Query: 444 AGETTPLGEARGPCWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLRRGR 503
           +G+  P G+   P +   G       RG PG   G  G RG    RG  G      R+G 
Sbjct: 501 SGQPGPKGDPGRPGFSYPGP------RGAPGE-KGEPGPRGPEGGRGDFGLKGEPGRKGE 553

Query: 504 ----GMPGRVGNGVGEG-RGASEPEGEPEP 528
                 PG  G     G RG   PEGEP P
Sbjct: 554 KGEPADPGPPGEPGPRGPRGVPGPEGEPGP 583


>gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Homo
           sapiens]
          Length = 918

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 107/400 (26%), Positives = 131/400 (32%), Gaps = 68/400 (17%)

Query: 452 EARGPCWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLRRGR-GMPGRVG 510
           EA G C+K       G         +G  G RG   A+G  G      ++GR G PG  G
Sbjct: 241 EAYGECYKVSCLEIPGP--------SGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEG 292

Query: 511 NGVGEGRGASEPEGEPEPRARADL--EVLQAGFERLQSLPELAERLGGRCPGQVAHGVLA 568
                      P G P P+       E  + G +  +  P LA + G    GQ   G L 
Sbjct: 293 -----------PIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNG--TDGQ--KGKLG 337

Query: 569 RAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGS 628
           R G       PG  G               G+     SP   RG +       R    G 
Sbjct: 338 RIGPPGCKGDPGNRGPD-------------GYPGEAGSPG-ERGDQGGKGDPGRPGRRGP 383

Query: 629 ALLAALNTLGPGSFGA--GLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGR---PA 683
                     PG  GA    G QG  S  P  P V G++ G   P  P +G PGR   P 
Sbjct: 384 ----------PGEIGAKGSKGYQG-NSGAPGSPGVKGAKGG-PGPRGP-KGEPGRRGDPG 430

Query: 684 FLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFP-VRGAGPIAGRRRRRGWTF 742
              SPG  GP    G      P G      ++    DR  P  RG     G   ++G   
Sbjct: 431 TKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQG--- 487

Query: 743 AAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAP-GFSGLC 801
                +G P +  P   +  P             P  RG A      P P  P G  G  
Sbjct: 488 ----SRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRG-APGEKGEPGPRGPEGGRGDF 542

Query: 802 VLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAG 841
            L+  P R    G P+  GP G PG R     P    E G
Sbjct: 543 GLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPG 582



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 30/90 (33%), Positives = 35/90 (38%), Gaps = 12/90 (13%)

Query: 444 AGETTPLGEARGPCWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLRRGR 503
           +G+  P G+   P +   G       RG PG   G  G RG    RG  G      R+G 
Sbjct: 501 SGQPGPKGDPGRPGFSYPGP------RGAPGE-KGEPGPRGPEGGRGDFGLKGEPGRKGE 553

Query: 504 ----GMPGRVGNGVGEG-RGASEPEGEPEP 528
                 PG  G     G RG   PEGEP P
Sbjct: 554 KGEPADPGPPGEPGPRGPRGVPGPEGEPGP 583


>gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Homo
           sapiens]
          Length = 1019

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 107/400 (26%), Positives = 131/400 (32%), Gaps = 68/400 (17%)

Query: 452 EARGPCWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLRRGR-GMPGRVG 510
           EA G C+K       G         +G  G RG   A+G  G      ++GR G PG  G
Sbjct: 241 EAYGECYKVSCLEIPGP--------SGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEG 292

Query: 511 NGVGEGRGASEPEGEPEPRARADL--EVLQAGFERLQSLPELAERLGGRCPGQVAHGVLA 568
                      P G P P+       E  + G +  +  P LA + G    GQ   G L 
Sbjct: 293 -----------PIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNG--TDGQ--KGKLG 337

Query: 569 RAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGS 628
           R G       PG  G               G+     SP   RG +       R    G 
Sbjct: 338 RIGPPGCKGDPGNRGPD-------------GYPGEAGSPG-ERGDQGGKGDPGRPGRRGP 383

Query: 629 ALLAALNTLGPGSFGA--GLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGR---PA 683
                     PG  GA    G QG  S  P  P V G++ G   P  P +G PGR   P 
Sbjct: 384 ----------PGEIGAKGSKGYQG-NSGAPGSPGVKGAKGG-PGPRGP-KGEPGRRGDPG 430

Query: 684 FLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFP-VRGAGPIAGRRRRRGWTF 742
              SPG  GP    G      P G      ++    DR  P  RG     G   ++G   
Sbjct: 431 TKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQG--- 487

Query: 743 AAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAP-GFSGLC 801
                +G P +  P   +  P             P  RG A      P P  P G  G  
Sbjct: 488 ----SRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRG-APGEKGEPGPRGPEGGRGDF 542

Query: 802 VLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAG 841
            L+  P R    G P+  GP G PG R     P    E G
Sbjct: 543 GLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPG 582



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 30/90 (33%), Positives = 35/90 (38%), Gaps = 12/90 (13%)

Query: 444 AGETTPLGEARGPCWKARGAVPSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLRRGR 503
           +G+  P G+   P +   G       RG PG   G  G RG    RG  G      R+G 
Sbjct: 501 SGQPGPKGDPGRPGFSYPGP------RGAPGE-KGEPGPRGPEGGRGDFGLKGEPGRKGE 553

Query: 504 ----GMPGRVGNGVGEG-RGASEPEGEPEP 528
                 PG  G     G RG   PEGEP P
Sbjct: 554 KGEPADPGPPGEPGPRGPRGVPGPEGEPGP 583


>gi|22027607 alpha 1 type XIII collagen isoform 18 [Homo sapiens]
          Length = 655

 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 92/407 (22%), Positives = 132/407 (32%), Gaps = 72/407 (17%)

Query: 460 ARGA--VPSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLRRGRGMPGRVGNGVGEGR 517
           A+GA  +    ++G PG + G  G +GA  + G  G     L   +G  G  GN +G GR
Sbjct: 269 AKGAPGIAVAGMKGEPG-IPGTKGEKGAEGSPGLPG-----LLGQKGEKGDAGNSIGGGR 322

Query: 518 GASEPEGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAA 577
           G   P G P P                                    G    AG+     
Sbjct: 323 GEPGPPGLPGP-----------------------------------PGPKGEAGVDGQVG 347

Query: 578 RPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTL 637
            PG  G   +R    AA + G        P+  +GS+     +   +++   +  AL  +
Sbjct: 348 PPGQPGDKGERG---AAGEQG--------PDGPKGSKGEPG-KGEMVDYNGNINEALQEI 395

Query: 638 GPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP----ERGSPGRPAFLRSPGLCGP 693
              +     G  G +   P  P + G +  +  P  P    E+G  G+P  +  PG  GP
Sbjct: 396 RTLALMGPPGLPG-QIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGP 454

Query: 694 GPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGP-IAGRRRRRGWTFAAALRKGAPR 752
              PG    P   G      S  +  ++    +   P   G    +G   A       P 
Sbjct: 455 ---PGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPGAEVPGLPGP- 510

Query: 753 EQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRG 812
           E PP  P       P+       A   +G       R     PG SGL      P     
Sbjct: 511 EGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGASGLDGRPGPPGTPGP 570

Query: 813 LGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPR 859
           +GVP   GP G  G +           AG         GL+ PP  +
Sbjct: 571 IGVPGPAGPKGERGSKGDPGMTGPTGAAGL-------PGLHGPPGDK 610



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 76/291 (26%), Positives = 107/291 (36%), Gaps = 40/291 (13%)

Query: 551 AERLGGRCPGQV-AHG----VLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVV 605
           A   G R PG++ A G    V ARA   A    PG  G       +LA + L  + T  +
Sbjct: 9   AAATGARGPGELGAPGTVALVAARAERGARLPSPGSCGLLTLALCSLALSLLAHFRTAEL 68

Query: 606 SPNLRRGSRRAGNHRVREIEFGSALLAALNTL--GPGSFGAGLGAQGPRSSTPEC---PV 660
              + R     G  ++      +A+L  +N L        +    + P++S P C   P 
Sbjct: 69  QARVLRLEAERGEQQME-----TAILGRVNQLLDEKWKLHSRRRREAPKTS-PGCNCPPA 122

Query: 661 VNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLAD 720
             GS       +   RG PG+P     PG  GP  + G    P P     GD        
Sbjct: 123 PQGSPGDAGLSIIGPRGPPGQPGTRGFPGFPGPIGLDGKPGHPGP----KGDMGLTGPPG 178

Query: 721 RAFPV--RGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPR 778
           +  P   +G     G    RG    A++      + PP  P       P  P      P 
Sbjct: 179 QPGPQGQKGEKGQCGEYPHRGEQSQASI------QGPPGPPG------PPGPSGPLGHPG 226

Query: 779 LRGRATAVAPRPLPAAPGFSGLCVLQPFPAR--SRGL-GVPSQQGPTGSPG 826
           L G    + P  LP  PG  G   +Q +  R   RG+ G+P + G  G+PG
Sbjct: 227 LPG---PMGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPG 274



 Score = 34.3 bits (77), Expect = 0.52
 Identities = 52/205 (25%), Positives = 67/205 (32%), Gaps = 30/205 (14%)

Query: 647 GAQGPRSSTPECPVV----NGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSV 702
           G QG +    +C         S+  +  P  P  G PG    L  PGL GP   PG    
Sbjct: 181 GPQGQKGEKGQCGEYPHRGEQSQASIQGPPGPP-GPPGPSGPLGHPGLPGPMGPPGLPGP 239

Query: 703 PTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWT-FAAALRKGAPR------EQP 755
           P P G            +R  P      + G+   +G    A A  KG P       E+ 
Sbjct: 240 PGPKGDPGIQGYHGRKGERGMP-----GMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKG 294

Query: 756 PASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGV 815
                  P    +  EK      + G      P  LP  PG  G              GV
Sbjct: 295 AEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEA------------GV 342

Query: 816 PSQQGPTGSPGCR-DRASAPRAGAE 839
             Q GP G PG + +R +A   G +
Sbjct: 343 DGQVGPPGQPGDKGERGAAGEQGPD 367



 Score = 33.9 bits (76), Expect = 0.67
 Identities = 31/82 (37%), Positives = 32/82 (39%), Gaps = 11/82 (13%)

Query: 22  GEKGEKRRTKQIIAAQAGGEGGRAQPGLPCSVDLATGLEGPLGGPAVDLDVGFSPGDDIA 81
           G+KGEK      I    GG G    PGLP       G  GP G   VD  VG  PG    
Sbjct: 306 GQKGEKGDAGNSIG---GGRGEPGPPGLP-------GPPGPKGEAGVDGQVG-PPGQPGD 354

Query: 82  GQSLGAAGGQVVHLPGGQLAVP 103
               GAAG Q    P G    P
Sbjct: 355 KGERGAAGEQGPDGPKGSKGEP 376



 Score = 31.2 bits (69), Expect = 4.4
 Identities = 21/49 (42%), Positives = 24/49 (48%), Gaps = 3/49 (6%)

Query: 21  PGEKGEKRRTKQIIAAQAGGEGG-RAQPGLPCSVDLATGLEGPLGGPAV 68
           PGEKGEK  T Q  +    GE G +  PG    V    G EGP G P +
Sbjct: 473 PGEKGEKGETGQAGSPGEKGEAGEKGNPG--AEVPGLPGPEGPPGPPGL 519



 Score = 30.0 bits (66), Expect = 9.7
 Identities = 26/81 (32%), Positives = 33/81 (40%), Gaps = 7/81 (8%)

Query: 454 RGPCWKARGAVPSGRLRGRPGR-----VAGASGRRGASQARGGTGRAPARLRRG-RGMPG 507
           +GP  K     P G  +G PG+     V G +G  G+   +G  G        G +G  G
Sbjct: 437 KGPRGKPGDMGPPGP-QGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAG 495

Query: 508 RVGNGVGEGRGASEPEGEPEP 528
             GN   E  G   PEG P P
Sbjct: 496 EKGNPGAEVPGLPGPEGPPGP 516


>gi|22027603 alpha 1 type XIII collagen isoform 16 [Homo sapiens]
          Length = 660

 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 92/407 (22%), Positives = 132/407 (32%), Gaps = 72/407 (17%)

Query: 460 ARGA--VPSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLRRGRGMPGRVGNGVGEGR 517
           A+GA  +    ++G PG + G  G +GA  + G  G     L   +G  G  GN +G GR
Sbjct: 274 AKGAPGIAVAGMKGEPG-IPGTKGEKGAEGSPGLPG-----LLGQKGEKGDAGNSIGGGR 327

Query: 518 GASEPEGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAA 577
           G   P G P P                                    G    AG+     
Sbjct: 328 GEPGPPGLPGP-----------------------------------PGPKGEAGVDGQVG 352

Query: 578 RPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTL 637
            PG  G   +R    AA + G        P+  +GS+     +   +++   +  AL  +
Sbjct: 353 PPGQPGDKGERG---AAGEQG--------PDGPKGSKGEPG-KGEMVDYNGNINEALQEI 400

Query: 638 GPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP----ERGSPGRPAFLRSPGLCGP 693
              +     G  G +   P  P + G +  +  P  P    E+G  G+P  +  PG  GP
Sbjct: 401 RTLALMGPPGLPG-QIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGP 459

Query: 694 GPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGP-IAGRRRRRGWTFAAALRKGAPR 752
              PG    P   G      S  +  ++    +   P   G    +G   A       P 
Sbjct: 460 ---PGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPGAEVPGLPGP- 515

Query: 753 EQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRG 812
           E PP  P       P+       A   +G       R     PG SGL      P     
Sbjct: 516 EGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGASGLDGRPGPPGTPGP 575

Query: 813 LGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPR 859
           +GVP   GP G  G +           AG         GL+ PP  +
Sbjct: 576 IGVPGPAGPKGERGSKGDPGMTGPTGAAGL-------PGLHGPPGDK 615



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 77/299 (25%), Positives = 111/299 (37%), Gaps = 51/299 (17%)

Query: 551 AERLGGRCPGQV-AHG----VLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVV 605
           A   G R PG++ A G    V ARA   A    PG  G       +LA + L  + T  +
Sbjct: 9   AAATGARGPGELGAPGTVALVAARAERGARLPSPGSCGLLTLALCSLALSLLAHFRTAEL 68

Query: 606 SPNLRRGSRRAGNHRVREIEFGSALLAALNTL--GPGSFGAGLGAQGPRSSTPEC---PV 660
              + R     G  ++      +A+L  +N L        +    + P++S P C   PV
Sbjct: 69  QARVLRLEAERGEQQME-----TAILGRVNQLLDEKWKLHSRRRREAPKTS-PGCNCPPV 122

Query: 661 VNGSEW-----GLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSE 715
             G        G   P+  + G PG P      GL GP   PG      P G+       
Sbjct: 123 FQGQPGTRGFPGFPGPIGLD-GKPGHPGPKGDMGLTGPPGQPG------PQGQKGEKGQC 175

Query: 716 ADLADRAFPVRGA-----GPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAP 770
            +   R  P+  +      P+  RR  +G    A++      + PP  P       P  P
Sbjct: 176 GEYPHRLLPLLNSVRLAPPPVIKRRTFQGEQSQASI------QGPPGPPG------PPGP 223

Query: 771 EKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPAR--SRGL-GVPSQQGPTGSPG 826
                 P L G    + P  LP  PG  G   +Q +  R   RG+ G+P + G  G+PG
Sbjct: 224 SGPLGHPGLPG---PMGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPG 279



 Score = 33.9 bits (76), Expect = 0.67
 Identities = 31/82 (37%), Positives = 32/82 (39%), Gaps = 11/82 (13%)

Query: 22  GEKGEKRRTKQIIAAQAGGEGGRAQPGLPCSVDLATGLEGPLGGPAVDLDVGFSPGDDIA 81
           G+KGEK      I    GG G    PGLP       G  GP G   VD  VG  PG    
Sbjct: 311 GQKGEKGDAGNSIG---GGRGEPGPPGLP-------GPPGPKGEAGVDGQVG-PPGQPGD 359

Query: 82  GQSLGAAGGQVVHLPGGQLAVP 103
               GAAG Q    P G    P
Sbjct: 360 KGERGAAGEQGPDGPKGSKGEP 381



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 48/184 (26%), Positives = 61/184 (33%), Gaps = 26/184 (14%)

Query: 664 SEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAF 723
           S+  +  P  P  G PG    L  PGL GP   PG    P P G            +R  
Sbjct: 207 SQASIQGPPGPP-GPPGPSGPLGHPGLPGPMGPPGLPGPPGPKGDPGIQGYHGRKGERGM 265

Query: 724 PVRGAGPIAGRRRRRGWT-FAAALRKGAPR------EQPPASPAASPCQAPRAPEKETEA 776
           P      + G+   +G    A A  KG P       E+        P    +  EK    
Sbjct: 266 P-----GMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAG 320

Query: 777 PRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCR-DRASAPR 835
             + G      P  LP  PG  G              GV  Q GP G PG + +R +A  
Sbjct: 321 NSIGGGRGEPGPPGLPGPPGPKGEA------------GVDGQVGPPGQPGDKGERGAAGE 368

Query: 836 AGAE 839
            G +
Sbjct: 369 QGPD 372



 Score = 31.2 bits (69), Expect = 4.4
 Identities = 21/49 (42%), Positives = 24/49 (48%), Gaps = 3/49 (6%)

Query: 21  PGEKGEKRRTKQIIAAQAGGEGG-RAQPGLPCSVDLATGLEGPLGGPAV 68
           PGEKGEK  T Q  +    GE G +  PG    V    G EGP G P +
Sbjct: 478 PGEKGEKGETGQAGSPGEKGEAGEKGNPG--AEVPGLPGPEGPPGPPGL 524



 Score = 30.0 bits (66), Expect = 9.7
 Identities = 26/81 (32%), Positives = 33/81 (40%), Gaps = 7/81 (8%)

Query: 454 RGPCWKARGAVPSGRLRGRPGR-----VAGASGRRGASQARGGTGRAPARLRRG-RGMPG 507
           +GP  K     P G  +G PG+     V G +G  G+   +G  G        G +G  G
Sbjct: 442 KGPRGKPGDMGPPGP-QGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAG 500

Query: 508 RVGNGVGEGRGASEPEGEPEP 528
             GN   E  G   PEG P P
Sbjct: 501 EKGNPGAEVPGLPGPEGPPGP 521


>gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens]
          Length = 1712

 Score = 50.1 bits (118), Expect = 9e-06
 Identities = 107/389 (27%), Positives = 133/389 (34%), Gaps = 70/389 (17%)

Query: 469  LRGRPGRVAGASGRRGASQARGGTGR----APARLRRGRGMPGRVGNGVGEGR----GAS 520
            LRG PG  AGA G  G     G  GR     P      RG  G VG    +G     G  
Sbjct: 703  LRGIPG-FAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLP 761

Query: 521  EPEGEP------------EPRARADLEVLQAGFERLQSLPELAERLGGR----CPGQVAH 564
             P+G P            +P  R D  V   G   L+ LP      G R     PG    
Sbjct: 762  GPDGPPGERGLPGEVLGAQPGPRGDAGV--PGQPGLKGLPGDRGPPGFRGSQGMPGMP-- 817

Query: 565  GVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREI 624
            G+  + GL   + +PGL G         A  Q G     +  P +  G       R    
Sbjct: 818  GLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGP----LGLPGIP-GREGLPGDRGDPG 872

Query: 625  EFGSALLAALNTLGPGSFGAGL-GAQGPRSSTPECPVVNGSEWGLAAP-LSPERGSPGRP 682
            + G+     +  L      AG  G QG     P  P   G +     P L  +RGSPG  
Sbjct: 873  DTGAPGPVGMKGLSGDRGDAGFTGEQGH----PGSPGFKGIDGMPGTPGLKGDRGSPGMD 928

Query: 683  AFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTF 742
             F   PGL G    PG         +G   F         F + G   +AG    +G   
Sbjct: 929  GFQGMPGLKGRPGFPGS--------KGEAGF---------FGIPGLKGLAGEPGFKG--- 968

Query: 743  AAALRKGAPREQPPASPAASPCQAPRAPEKETEAPR-LRGRATAVAPRPLPAAPGFSGLC 801
                 +G P    P  P   P       EK  E P  L+G   A   + +P  PG SG+ 
Sbjct: 969  ----SRGDPGPPGPP-PVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIP 1023

Query: 802  VLQPFPARSRG----LGVPSQQGPTGSPG 826
             L   P   +G    +GVP   G  G PG
Sbjct: 1024 GLPGRPGHIKGVKGDIGVPGIPGLPGFPG 1052



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 100/399 (25%), Positives = 132/399 (33%), Gaps = 62/399 (15%)

Query: 465 PSGRLRGRPGRVA--GASGRRGASQARGGTGRAPARLRRGRGMPGRVGNGVGEG-RGASE 521
           P   ++G PG     G  G +G     G  G     L+  RG PG  G     G  G   
Sbjct: 592 PGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPG 651

Query: 522 PEGEPEPRARADLEVLQA-GFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPG 580
           P G P  +   D +V +A G +R +++           PG +        GL      PG
Sbjct: 652 PAGTPG-QIDCDTDVKRAVGGDRQEAIQ----------PGCIG----GPKGLPGLPGPPG 696

Query: 581 LAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPG 640
             G+   R +   A   GG            G R       RE   G         +GP 
Sbjct: 697 PTGAKGLRGIPGFAGADGG-----------PGPRGLPGDAGREGFPGPP-----GFIGPR 740

Query: 641 SFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP--ERGSPGRPAFLRSPGLCGPGPVPG 698
                +G  GP  S    P+      GL  P  P  ERG PG       PG  G   VPG
Sbjct: 741 GSKGAVGLPGPDGSPG--PI------GLPGPDGPPGERGLPGE-VLGAQPGPRGDAGVPG 791

Query: 699 GLSVP-TPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALR--KGAPREQP 755
              +   P  RG   F  +        ++G   + G   + G      L    GAP ++ 
Sbjct: 792 QPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEG 851

Query: 756 PAS----PAASPCQAPRAPEKETEAPRL---------RGRATAVAPRPLPAAPGFSGLCV 802
           P      P        R    +T AP           RG A     +  P +PGF G+  
Sbjct: 852 PLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDG 911

Query: 803 LQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAG 841
           +   P      G P   G  G PG + R   P +  EAG
Sbjct: 912 MPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAG 950



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 59/201 (29%), Positives = 79/201 (39%), Gaps = 21/201 (10%)

Query: 639 PGSFGA--GLGAQGPRSSTPECPVVN--GSEWGLAAPLSP----ERGSPGRPAFLRSPGL 690
           PG  G    +GA GP+ +  +   +   G       P  P    + GSPGR      PGL
Sbjct: 529 PGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGL 588

Query: 691 CGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGA 750
             PGP   G+  P P   G                 G G + G + +RG+   A L  G 
Sbjct: 589 --PGPPGDGIKGP-PGDPGYPGIPGTKGTPGEMGPPGLG-LPGLKGQRGFPGDAGL-PGP 643

Query: 751 PREQPPASPAASPCQAPRAPEKETEAPRLRG--RATAVAPRPLPAAPGFSGLCVLQPFPA 808
           P    P  PA +P Q     + +T+  R  G  R  A+ P  +    G  GL    P P 
Sbjct: 644 PGFLGPPGPAGTPGQI----DCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGL-PGPPGPT 698

Query: 809 RSRGL-GVPSQQGPTGSPGCR 828
            ++GL G+P   G  G PG R
Sbjct: 699 GAKGLRGIPGFAGADGGPGPR 719



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 52/214 (24%), Positives = 67/214 (31%), Gaps = 31/214 (14%)

Query: 676 RGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEAD-----------LADRAFP 724
           RG PG P     PG  G    PG   +P P G   GD  +             + D   P
Sbjct: 362 RGDPGFPGAQGEPGSQGE---PGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIP 418

Query: 725 VRGAGPIA--GRRRRRGWT----------FAAALRKGAPREQPPASPAASPCQAPRAPEK 772
               GP    G+R   G            F   L+    R   P  P +   + P+  + 
Sbjct: 419 ALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKG 478

Query: 773 ETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCR---D 829
           +    R      A+  + LP  PG  G   +   P R    G P Q G  G PG +    
Sbjct: 479 DAGECRCTEGDEAI--KGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPG 536

Query: 830 RASAPRAGAEAGSMETFLRNGGLYPPPSPRAPAV 863
              AP      G   T    G    P  P  P +
Sbjct: 537 NIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGM 570



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 53/207 (25%), Positives = 68/207 (32%), Gaps = 27/207 (13%)

Query: 639  PGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP----------ERGSPGRPAFLRSP 688
            PG FG   G +GP    P    + GS+     P +P          + G  GRP     P
Sbjct: 1286 PGIFGLK-GYRGP-PGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLP 1343

Query: 689  GLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRK 748
            G  GP    G +    P G       +    D  FP  GA    G     G     A++ 
Sbjct: 1344 GEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFP--GAPGTVGAPGIAGIPQKIAVQP 1401

Query: 749  GAPREQPPASPAASPCQ-APRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFP 807
            G    Q    P  +P +  P+ P  E       G+A       + A PGF G        
Sbjct: 1402 GTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRG-------- 1453

Query: 808  ARSRGLGVPSQQGPTGSPGCRDRASAP 834
                  G    QGP G  G   R  +P
Sbjct: 1454 ----DEGPIGHQGPIGQEGAPGRPGSP 1476



 Score = 37.7 bits (86), Expect = 0.047
 Identities = 59/222 (26%), Positives = 78/222 (35%), Gaps = 39/222 (17%)

Query: 647  GAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPG-------- 698
            G  G  ++ P    V G +    AP   ERG PG P     PG+  P  + G        
Sbjct: 1229 GDPGEANTLPGPVGVPGQKGDQGAP--GERGPPGSPGLQGFPGITPPSNISGAPGDKGAP 1286

Query: 699  ---GLS----VPTPCGRGAGDFSEADLADRAFP----VRGAGPIAGRRRRRGWTFAAALR 747
               GL      P P G  A   S+ D  +   P     +G    +G + R G  F     
Sbjct: 1287 GIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPG-VFGLPGE 1345

Query: 748  KGAPREQP----PASPAASPCQAPRAPEKETEAPRLRGRATAVA----PRPLPAAPGFSG 799
            KG   EQ          A   + P+ P+ +   P   G   A      P+ +   PG  G
Sbjct: 1346 KGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVG 1405

Query: 800  LCVLQPFPARSRGL-GVPSQQGPTGSPGCRDRASAP-RAGAE 839
                   P   RG  G P + GP G PG      AP +AG +
Sbjct: 1406 -------PQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQ 1440



 Score = 37.4 bits (85), Expect = 0.061
 Identities = 44/167 (26%), Positives = 58/167 (34%), Gaps = 20/167 (11%)

Query: 667 GLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCG-------RGAGDFSEADLA 719
           G   P+ P+ G  G P     PGL G     G    P   G       RG   F  AD  
Sbjct: 61  GQPGPVGPQ-GYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGAD-- 117

Query: 720 DRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRL 779
                + G     G R R G+      +  +  + PP S   +    P+ P+ +   P  
Sbjct: 118 ----GIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYA 173

Query: 780 RGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPG 826
             +      R  P  PG  G    Q  P R   +G   Q GP G+PG
Sbjct: 174 LPKEERDRYRGEPGEPGLVG---FQGPPGRPGHVG---QMGPVGAPG 214



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 40/158 (25%), Positives = 55/158 (34%), Gaps = 30/158 (18%)

Query: 677  GSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRG-------AGDFSEADLADRAFPVRGAG 729
            G+PG P F    G+ G   +PG    P   G          G   E      A  + G  
Sbjct: 1182 GAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPV 1241

Query: 730  PIAGRRRRRGWTFAAALRKGAPREQ-PPASPAASPCQAPRAPEKETEAPRLRGRATAVAP 788
             + G++            +GAP E+ PP SP          P   + AP  +G       
Sbjct: 1242 GVPGQKG----------DQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKG------- 1284

Query: 789  RPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPG 826
                 APG  GL   +  P       +P  +G TG+PG
Sbjct: 1285 -----APGIFGLKGYRGPPGPPGSAALPGSKGDTGNPG 1317



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 56/194 (28%), Positives = 67/194 (34%), Gaps = 26/194 (13%)

Query: 647  GAQGPRSSTPECPVVNGSEWGLAAP----LSPERGSPGRPAFLRSPGLCGPGPVPGGLSV 702
            G QG    TP   + +G+     AP    L   RG PG P     PG  G    PG    
Sbjct: 1263 GLQGFPGITPPSNI-SGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGT 1321

Query: 703  PTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAAS 762
            P   G  AGD S        F + G     G +   G T       GA  ++ P  P   
Sbjct: 1322 PGTKG-WAGD-SGPQGRPGVFGLPGEKGPRGEQGFMGNTGPT----GAVGDRGPKGPKGD 1375

Query: 763  PCQAPRAPEKETEAPRLRGRATAVAPRP----------LPAAPGFSGLCVLQPFPARSRG 812
            P   P AP     AP + G    +A +P           P APG  G    Q  P     
Sbjct: 1376 P-GFPGAPGT-VGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGP---QGPPGEPGF 1430

Query: 813  LGVPSQQGPTGSPG 826
             G P + GP G  G
Sbjct: 1431 RGAPGKAGPQGRGG 1444



 Score = 30.0 bits (66), Expect = 9.7
 Identities = 32/125 (25%), Positives = 43/125 (34%), Gaps = 5/125 (4%)

Query: 639  PGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP----ERGSPGRPAFLRSPGLCGPG 694
            PG+ GA  G  G        P   G +     P +P     +G PG P F  +PG  GP 
Sbjct: 1382 PGTVGAP-GIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQ 1440

Query: 695  PVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQ 754
               G  +VP   G       +  +     P R   P       R  +    L K +  +Q
Sbjct: 1441 GRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQ 1500

Query: 755  PPASP 759
             P  P
Sbjct: 1501 EPMCP 1505


>gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens]
          Length = 1142

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 116/444 (26%), Positives = 151/444 (34%), Gaps = 83/444 (18%)

Query: 427 VGLAG--GIEAAVLLRGARAGETTPLGEARGPCWKARGAVPSGRLRGRPGRVA--GASGR 482
           VGL G  GI     ++G +      +G    P  K     P   L G PG     GA G 
Sbjct: 542 VGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGP 601

Query: 483 RGASQARGGTGRAPARLRRGRGMPGRVG-NGVG-EGR-GASEPEGEPEPRARADLEVLQA 539
           RG    RG  G          G PG +G  G+G  GR GA  P GEP             
Sbjct: 602 RGPKGERGLPGV--------HGSPGDIGPQGIGIPGRTGAQGPAGEP------------- 640

Query: 540 GFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLAGS-GVQRALALAA---A 595
           G +  + LP L    G   PG    GV  R G      +PGL G  G   AL L     A
Sbjct: 641 GIQGPRGLPGLPGTPG--TPGN--DGVPGRDG------KPGLPGPPGDPIALPLLGDIGA 690

Query: 596 QLGGWT-TCVVS-PNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRS 653
            L  +   C  S P L+      G       ++ S  +A    +GP       G +GP+ 
Sbjct: 691 LLKNFCGNCQASVPGLKSNKGEEGGAG-EPGKYDS--MARKGDIGPRGPPGIPGREGPKG 747

Query: 654 STPE--CPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAG 711
           S  E   P + G +         + G  G P    +PG  GP  + G    P P G    
Sbjct: 748 SKGERGYPGIPGEKG--------DEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGE 799

Query: 712 DFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPE 771
             S+        P     P      R G +    ++ G      P  P     +    P 
Sbjct: 800 KGSDGPPGKPGPPGPPGIPF---NERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPV 856

Query: 772 KETEA---------PRLRGRATAVAPRPL------PAAPGFSGLCVLQPFPARSRG---- 812
            E  A         P ++G      P  +      P APG  G+    P     RG    
Sbjct: 857 GEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGV----PGEPGERGPVGD 912

Query: 813 LGVPSQQGPTGSPGCRDRASAPRA 836
           +G P  +GP+G PG   +   P A
Sbjct: 913 IGFPGPEGPSGKPGINGKDGIPGA 936



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 102/426 (23%), Positives = 134/426 (31%), Gaps = 73/426 (17%)

Query: 461 RGAVPSGRLRGRPGRVAGASGRRGASQARGGTGRAPARLRRGRGMPGRVG-NGVGEGRGA 519
           +G      L G PG   G  G +G   ++G TG    +  +G   P   G NG    +G 
Sbjct: 309 KGEPGENGLHGAPG-FPGQKGEQGFEGSKGETGEKGEQGEKGD--PALAGLNGENGLKGD 365

Query: 520 SEPEGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCPGQVA--HGVLARAGLLAAAA 577
             P G P P+        + G       P L   LG + P       G   R G      
Sbjct: 366 LGPHGPPGPKG-------EKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPG 418

Query: 578 RPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTL 637
           +PG  G      +      LGG+       N       AG  +  + E G          
Sbjct: 419 KPGPPGPPGPPGIQGIHQTLGGYYN---KDNKGNDEHEAGGLKGDKGETGL--------- 466

Query: 638 GPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAP-------LSPERGSPGRPAFLRSPGL 690
            PG F   +G +G +    E P   G +     P       +  E G PG P  + SPGL
Sbjct: 467 -PG-FPGSVGPKGQKGEPGE-PFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGL 523

Query: 691 ---------CGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWT 741
                     GP   PG + +P   G       + +  D        G I G     G  
Sbjct: 524 KGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGD-------PGGIIGPPGLPGPK 576

Query: 742 FAAALRKGAPREQPPASPAASP---CQAPRAPEKETEAPRLRG--------------RAT 784
             A    G P +  P  P          PR P+ E   P + G              R  
Sbjct: 577 GEA----GPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTG 632

Query: 785 AVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPG-CRDRASAPRAGAEAGSM 843
           A  P   P   G  GL  L   P      GVP + G  G PG   D  + P  G     +
Sbjct: 633 AQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALL 692

Query: 844 ETFLRN 849
           + F  N
Sbjct: 693 KNFCGN 698



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 103/412 (25%), Positives = 135/412 (32%), Gaps = 63/412 (15%)

Query: 466 SGRLRGRPGRVA--GASGRRGASQARGGTGRAPARLRRG-RGMPGRVGNGVGEGRGASEP 522
           +G L+G  G     G  G  G    +G  G    +  +G RG PG +G+     +G    
Sbjct: 454 AGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGS-----QGVKGE 508

Query: 523 EGEPEPRARADLEVLQAGFERLQSLPELAERLGGRCP-GQVA----HGVLARAGLLAAAA 577
            G+P P           G   L+     A  +G R P G V     HG+  + G+     
Sbjct: 509 PGDPGPPGLI-------GSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKG 561

Query: 578 RPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGNHRVREIEFG-SALLAALNT 636
            PG  G      L     + G     +       G+  A   R  + E G   +  +   
Sbjct: 562 DPG--GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGD 619

Query: 637 LGPGSFG--AGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPG 694
           +GP   G     GAQGP             E G+  P    RG PG P    +PG  G  
Sbjct: 620 IGPQGIGIPGRTGAQGP-----------AGEPGIQGP----RGLPGLPG---TPGTPGND 661

Query: 695 PVPGGLSVPTPCGRGAGDFSEADLAD-----RAFPVRGAGPIAGRRRRRGWTFAAALRKG 749
            VPG    P   G      +   L D     + F       + G +  +G    A    G
Sbjct: 662 GVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGA----G 717

Query: 750 APREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPAR 809
            P +    S A      PR P      P   G   +   R  P  PG  G   LQ  P  
Sbjct: 718 EPGKYD--SMARKGDIGPRGPPG---IPGREGPKGSKGERGYPGIPGEKGDEGLQGIP-- 770

Query: 810 SRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAP 861
               G+P   GPTG PG   R   P      G   +    G   PP  P  P
Sbjct: 771 ----GIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIP 818



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 103/424 (24%), Positives = 139/424 (32%), Gaps = 72/424 (16%)

Query: 454  RGPCWKARGAVPSGRLRGRPGRVA----GASGRRGASQARGGTG-RAPARLRRGRGMPGR 508
            RGP  K    +P   + G PG +     G  GR GA    G  G + P  L    G PG 
Sbjct: 602  RGP--KGERGLPG--VHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGT 657

Query: 509  VGNGVGEGR----GASEPEGEPEPRAR-ADLEVLQAGF--ERLQSLPEL----AERLGGR 557
             GN    GR    G   P G+P       D+  L   F      S+P L     E  G  
Sbjct: 658  PGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAG 717

Query: 558  CPGQVAHGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAG 617
             PG+  +  +AR G +     PG+ G    +    +  + G        P +       G
Sbjct: 718  EPGK--YDSMARKGDIGPRGPPGIPGREGPKG---SKGERG-------YPGIPGEKGDEG 765

Query: 618  NHRVREIEFGSALLAALNTLG----PGSFGAG--LGAQGP--RSSTPECPVVNGSEWGLA 669
               +  I            +G    PG  GA    G+ GP  +   P  P +  +E    
Sbjct: 766  LQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGM 825

Query: 670  APLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAG 729
            + L   +G    P++   PG  GP   PG +  P   G    +       DR      AG
Sbjct: 826  SSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRG----PAG 881

Query: 730  P--IAGRRRRRGWTFAAALRKGAPREQPPAS---------PAASPC-------------- 764
            P  IAG   + G      +  G P E+ P           P+  P               
Sbjct: 882  PPGIAGMSGKPGAPGPPGV-PGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIM 940

Query: 765  --QAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPT 822
                 R P+ E     + G   +   R  P   G  G       P     +G P  QGP 
Sbjct: 941  GKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPP 1000

Query: 823  GSPG 826
            GSPG
Sbjct: 1001 GSPG 1004



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 26/73 (35%), Positives = 31/73 (42%), Gaps = 6/73 (8%)

Query: 465  PSGR--LRGRPGRVAGASGRRGASQARGGTGRAPARLRRGRGMPGRVGNGVGEGRGASEP 522
            P G+  L G PG   G  G RG    RG  G     L    G+PG    G+    GA  P
Sbjct: 1058 PPGKDGLPGPPGD-PGPQGYRGQKGERGEPGIG---LPGSPGLPGTSALGLPGSPGAPGP 1113

Query: 523  EGEPEPRARADLE 535
            +G P P  R + E
Sbjct: 1114 QGPPGPSGRCNPE 1126


>gi|239748777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 350

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 67/219 (30%), Positives = 81/219 (36%), Gaps = 31/219 (14%)

Query: 653 SSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGD 712
           + +P  P VN  +WG  A  +P   S    A   S       P PG +  P+     A  
Sbjct: 17  AESPARPRVN-EQWGSRAHPNPRSASSAAAAASSS------FPPPGFIHPPSS---RAAV 66

Query: 713 FSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAP--REQPPASPAA--------- 761
            S    A  A P      +AG   R G    + LR  A    +Q  A+P           
Sbjct: 67  HSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGP 126

Query: 762 SPCQAPRAPEKETEAPRLRGRATAVAPRP--LPAAPGFSGLCVLQPFPARSRGLGVPSQQ 819
           SP   PR+    T  PR    AT + P P   P A    G C   PFPARSR    P + 
Sbjct: 127 SPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPG-CRSSPFPARSR---TPGEA 182

Query: 820 GPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSP 858
           GP   P    R  APR G +       LR      PPSP
Sbjct: 183 GP---PRGDPRPRAPRPG-DHPRRSPALRETPSLSPPSP 217


>gi|239756550 PREDICTED: hypothetical protein XP_002344932 [Homo
           sapiens]
          Length = 177

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 51/159 (32%), Positives = 59/159 (37%), Gaps = 27/159 (16%)

Query: 716 ADLADRAFPVRGAGPIAGRRRR-----RGWTFAAALRKGAPREQPPASPAASPCQAPRAP 770
           A L     P RG  P  G R R     R     + L   AP   P AS +  P    RAP
Sbjct: 27  AGLGPGPSPRRGRLPSGGLRLRARPGRRALGLPSPLELAAPSLVPNASASPRPVSCRRAP 86

Query: 771 EKETE-APRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRD 829
            +    A R RGR     P P P +P         P P R+R LG P +     +P  R 
Sbjct: 87  PRPVPGAARWRGR-----PEPRPGSPA-------GPAPTRARPLGAPGR----SAPPARR 130

Query: 830 RASAPRAGAEAGSMETFLRNGGLYPPPSPRAPAVCVQHL 868
           R       A  G  E  LR     P    RA AVC  H+
Sbjct: 131 RERELGTDARVGDGERELR-----PDARGRAEAVCSDHV 164



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 46/150 (30%), Positives = 60/150 (40%), Gaps = 19/150 (12%)

Query: 392 KTEPPALIQAPWGVHPGQ-----HLPLQLIDLALQQILEAVGLAGGIE-AAVLLRGARAG 445
           +T  PA++    G+ PG       LP   + L  +    A+GL   +E AA  L    + 
Sbjct: 19  RTVRPAMLA---GLGPGPSPRRGRLPSGGLRLRARPGRRALGLPSPLELAAPSLVPNASA 75

Query: 446 ETTPLGEARGPCWKARGAVP-SGRLRGRPGRVAGASGRRGASQARGGTGRAPARLR-RGR 503
              P+   R P     GA    GR   RPG  AG +  R       G    PAR R R  
Sbjct: 76  SPRPVSCRRAPPRPVPGAARWRGRPEPRPGSPAGPAPTRARPLGAPGRSAPPARRREREL 135

Query: 504 GMPGRVGNGVGEGRGASEPEGEPEPRARAD 533
           G   RVG+G        E E  P+ R RA+
Sbjct: 136 GTDARVGDG--------ERELRPDARGRAE 157


>gi|239745514 PREDICTED: hypothetical protein XP_002343509 [Homo
           sapiens]
          Length = 177

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 51/159 (32%), Positives = 59/159 (37%), Gaps = 27/159 (16%)

Query: 716 ADLADRAFPVRGAGPIAGRRRR-----RGWTFAAALRKGAPREQPPASPAASPCQAPRAP 770
           A L     P RG  P  G R R     R     + L   AP   P AS +  P    RAP
Sbjct: 27  AGLGPGPSPRRGRLPSGGLRLRARPGRRALGLPSPLELAAPSLVPNASASPRPVSCRRAP 86

Query: 771 EKETE-APRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRD 829
            +    A R RGR     P P P +P         P P R+R LG P +     +P  R 
Sbjct: 87  PRPVPGAARWRGR-----PEPRPGSPA-------GPAPTRARPLGAPGR----SAPPARR 130

Query: 830 RASAPRAGAEAGSMETFLRNGGLYPPPSPRAPAVCVQHL 868
           R       A  G  E  LR     P    RA AVC  H+
Sbjct: 131 RERELGTDARVGDGERELR-----PDARGRAEAVCSDHV 164



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 46/150 (30%), Positives = 60/150 (40%), Gaps = 19/150 (12%)

Query: 392 KTEPPALIQAPWGVHPGQ-----HLPLQLIDLALQQILEAVGLAGGIE-AAVLLRGARAG 445
           +T  PA++    G+ PG       LP   + L  +    A+GL   +E AA  L    + 
Sbjct: 19  RTVRPAMLA---GLGPGPSPRRGRLPSGGLRLRARPGRRALGLPSPLELAAPSLVPNASA 75

Query: 446 ETTPLGEARGPCWKARGAVP-SGRLRGRPGRVAGASGRRGASQARGGTGRAPARLR-RGR 503
              P+   R P     GA    GR   RPG  AG +  R       G    PAR R R  
Sbjct: 76  SPRPVSCRRAPPRPVPGAARWRGRPEPRPGSPAGPAPTRARPLGAPGRSAPPARRREREL 135

Query: 504 GMPGRVGNGVGEGRGASEPEGEPEPRARAD 533
           G   RVG+G        E E  P+ R RA+
Sbjct: 136 GTDARVGDG--------ERELRPDARGRAE 157


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.138    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,087,403
Number of Sequences: 37866
Number of extensions: 2822027
Number of successful extensions: 20413
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 78
Number of HSP's successfully gapped in prelim test: 943
Number of HSP's that attempted gapping in prelim test: 13244
Number of HSP's gapped (non-prelim): 4727
length of query: 870
length of database: 18,247,518
effective HSP length: 111
effective length of query: 759
effective length of database: 14,044,392
effective search space: 10659693528
effective search space used: 10659693528
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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