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Search of human proteins with 239744258
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239744258 PREDICTED: hypothetical protein LOC100128703 [Homo
sapiens]
(389 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239744258 PREDICTED: hypothetical protein LOC100128703 [Homo ... 834 0.0
gi|239755454 PREDICTED: hypothetical protein [Homo sapiens] 590 e-169
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 101 1e-21
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 100 4e-21
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 97 2e-20
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 97 2e-20
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 96 7e-20
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 95 9e-20
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 95 1e-19
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 95 1e-19
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 95 1e-19
gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] 95 1e-19
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 94 2e-19
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 94 2e-19
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 94 2e-19
gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [H... 94 2e-19
gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Ho... 94 2e-19
gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Hom... 94 2e-19
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 93 5e-19
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 93 5e-19
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] 91 2e-18
gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens] 90 3e-18
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 89 5e-18
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 89 5e-18
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 89 5e-18
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 89 5e-18
gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s... 89 9e-18
gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s... 89 9e-18
gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo ... 89 9e-18
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 88 1e-17
>gi|239744258 PREDICTED: hypothetical protein LOC100128703 [Homo
sapiens]
Length = 389
Score = 834 bits (2154), Expect = 0.0
Identities = 389/389 (100%), Positives = 389/389 (100%)
Query: 1 MTPSRAQEGPPRVERAECGASAGALTIVSSHGGDSDKDLCARTQIYGAQPREDQMGSVEK 60
MTPSRAQEGPPRVERAECGASAGALTIVSSHGGDSDKDLCARTQIYGAQPREDQMGSVEK
Sbjct: 1 MTPSRAQEGPPRVERAECGASAGALTIVSSHGGDSDKDLCARTQIYGAQPREDQMGSVEK 60
Query: 61 LTTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVAS 120
LTTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVAS
Sbjct: 61 LTTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVAS 120
Query: 121 PGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQK 180
PGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQK
Sbjct: 121 PGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQK 180
Query: 181 GECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECG 240
GECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECG
Sbjct: 181 GECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECG 240
Query: 241 VPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWT 300
VPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWT
Sbjct: 241 VPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWT 300
Query: 301 EGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREGRV 360
EGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREGRV
Sbjct: 301 EGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREGRV 360
Query: 361 WYSLDKRGSVPAALASQRHALLALPQPQG 389
WYSLDKRGSVPAALASQRHALLALPQPQG
Sbjct: 361 WYSLDKRGSVPAALASQRHALLALPQPQG 389
>gi|239755454 PREDICTED: hypothetical protein [Homo sapiens]
Length = 305
Score = 590 bits (1521), Expect = e-169
Identities = 276/286 (96%), Positives = 279/286 (97%)
Query: 1 MTPSRAQEGPPRVERAECGASAGALTIVSSHGGDSDKDLCARTQIYGAQPREDQMGSVEK 60
MTPSRAQEGPPRVERAECGASAGALTIVSSHGGDSDKDLCARTQIYGAQPREDQMGSVEK
Sbjct: 1 MTPSRAQEGPPRVERAECGASAGALTIVSSHGGDSDKDLCARTQIYGAQPREDQMGSVEK 60
Query: 61 LTTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVAS 120
LTTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVAS
Sbjct: 61 LTTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVAS 120
Query: 121 PGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQK 180
PGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQK
Sbjct: 121 PGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQK 180
Query: 181 GECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECG 240
GECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECG
Sbjct: 181 GECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECG 240
Query: 241 VPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASV 286
VPWREG VWRPL+RRGSVASPGEKGECGV W EG VW L++R SV
Sbjct: 241 VPWREGAVWRPLDRRGSVASPGEKGECGVRWREGRVWYSLDKRGSV 286
Score = 433 bits (1114), Expect = e-121
Identities = 195/212 (91%), Positives = 201/212 (94%)
Query: 178 GQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKG 237
G+KGECG+PW EG VWRPLERR SVASPGEKGECGVPWREGRVWRPL+RR SVASPG+KG
Sbjct: 94 GEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKG 153
Query: 238 ECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGV 297
ECGVPWREG VWRPLERR SVASPG+KGECGVPW EGGVWRPLERR SVASPGEKGECGV
Sbjct: 154 ECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVASPGEKGECGV 213
Query: 298 PWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWRE 357
PW EG VWRPLERRASVASPG+KGECGVPWREG VWRPLDRRGSVASPGEKGECGVRWRE
Sbjct: 214 PWREGRVWRPLERRASVASPGQKGECGVPWREGAVWRPLDRRGSVASPGEKGECGVRWRE 273
Query: 358 GRVWYSLDKRGSVPAALASQRHALLALPQPQG 389
GRVWYSLDKRGSVPAALASQRHALLALPQPQG
Sbjct: 274 GRVWYSLDKRGSVPAALASQRHALLALPQPQG 305
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 101 bits (251), Expect = 1e-21
Identities = 97/311 (31%), Positives = 121/311 (38%), Gaps = 48/311 (15%)
Query: 69 AKPGSVPA---PRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKG 125
A P +P P R G AG AAGE G G+P G P S PG G
Sbjct: 494 AGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMP----GSPGGPGSDG 549
Query: 126 ECGVPWREGRVWR--------PLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASP 177
+ G P +G R P + G + PG KG G P + G P P
Sbjct: 550 KPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGP-GGPGPQGPP 608
Query: 178 GQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKG 237
G+ GE G P G P +G PG +G G+P G P PG KG
Sbjct: 609 GKNGETG-PQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGG----PPGENGKPGEPGPKG 663
Query: 238 ECGVPWR---EGPVWRPLER--RGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEK 292
+ G P +G P ER G +PG +G G P EGG + + PG
Sbjct: 664 DAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGG-------KGAAGPPGPP 716
Query: 293 GECGVPWTEGGVWRPLERRASVASPGEKGE---------CGVPWREG--GVWRPLDRRGS 341
G G P +G P E R + SPG KG+ GVP ++G G P+ G
Sbjct: 717 GAAGTPGLQG---MPGE-RGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGP 772
Query: 342 VASPGEKGECG 352
PG+KGE G
Sbjct: 773 AGQPGDKGEGG 783
Score = 92.8 bits (229), Expect = 5e-19
Identities = 93/301 (30%), Positives = 115/301 (38%), Gaps = 35/301 (11%)
Query: 71 PGSVPAPRPLRSIDGEAGH---SEAAGEKGECGIPWTEGQVWRPLERRA-----SVASPG 122
P + P + G GH GEKGE G P +G+ P E A +PG
Sbjct: 247 PPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPG 306
Query: 123 EKGECGVPWREGRVWRPLDR--RGSVASPGEKGECGVPWREG--GVWRPLERRASVASPG 178
E+G G+P G R G PG G G P G G P S +PG
Sbjct: 307 ERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPG 366
Query: 179 QKGECGVPWREGGVWRPLERRGSVASPGEKGE---CGVPWREGRVWR--PLERRASVASP 233
Q+GE G P G P G SPG KGE G+P G + P + +P
Sbjct: 367 QRGEPG-PQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAP 425
Query: 234 GQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKG 293
G +G G P + G +G GE+GE G+P G SPGE G
Sbjct: 426 GLRGGAGEPGKNG-------AKGEPGPRGERGEAGIPGVPGAKGED----GKDGSPGEPG 474
Query: 294 ECGVPWTEGGVWRPLERRASVAS--PGEKGECGVPWREGGVWRPLDRRGSVASPGEKGEC 351
G+P G P R + + PGEKG G E G P RG+ PG G
Sbjct: 475 ANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAG----ERGAPGPAGPRGAAGEPGRDGVP 530
Query: 352 G 352
G
Sbjct: 531 G 531
Score = 92.0 bits (227), Expect = 8e-19
Identities = 91/295 (30%), Positives = 117/295 (39%), Gaps = 51/295 (17%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
PG++ P DGE+G GE+G G P +G P PG KG G
Sbjct: 218 PGAIGPSGPAGK-DGESGRPGRPGERGLPGPPGIKGPAGIP-------GFPGMKGHRGFD 269
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
R G +G +PG KGE G+P E G P+ R +PG++G G+P G
Sbjct: 270 GRNG-------EKGETGAPGLKGENGLP-GENGAPGPMGPR---GAPGERGRPGLPGAAG 318
Query: 191 GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWR 250
RG+ + G G+ G P G P SPG KGE G
Sbjct: 319 A-------RGNDGARGSDGQPGPPGPPGTAGFP-------GSPGAKGEVG---------- 354
Query: 251 PLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGE---CGVPWTEG--GVW 305
P GS +PG++GE G P G P SPG KGE G+P G G
Sbjct: 355 PAGSPGSNGAPGQRGEPG-PQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGAR 413
Query: 306 RPLERRASVASPGEKGECGVPWREGGVWRPLDR--RGSVASPGEKGECGVRWREG 358
P + +PG +G G P + G P R RG PG G G ++G
Sbjct: 414 GPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDG 468
Score = 88.2 bits (217), Expect = 1e-17
Identities = 86/286 (30%), Positives = 103/286 (36%), Gaps = 46/286 (16%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
P P + G G AAG G G+P G + P + PG G GVP ++G
Sbjct: 701 PGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSP-GPKGDKGEPGGPGADGVPGKDG 759
Query: 135 R--VWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGV 192
P+ G PG+KGE G P G SPG++GE G P G
Sbjct: 760 PRGPTGPIGPPGPAGQPGDKGEGGAPGLPG-------IAGPRGSPGERGETGPPGPAGFP 812
Query: 193 WRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPL 252
P G PG KGE G P +G P PG G G P +G
Sbjct: 813 GAP----GQNGEPGGKGERGAPGEKGEGGPP----GVAGPPGGSGPAGPPGPQGV----- 859
Query: 253 ERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRA 312
+G SPG G G P G P S +PG G G P +G
Sbjct: 860 --KGERGSPGGPGAAGFPGARGLPGPP----GSNGNPGPPGPSGSPGKDG---------- 903
Query: 313 SVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
PG G G P GV P +G PGEKG G + G
Sbjct: 904 ---PPGPAGNTGAP-GSPGVSGP---KGDAGQPGEKGSPGAQGPPG 942
Score = 87.0 bits (214), Expect = 3e-17
Identities = 84/276 (30%), Positives = 109/276 (39%), Gaps = 46/276 (16%)
Query: 82 SIDGEAGHSEAAGEKGECGIPWTEGQVWRPLE--RRASVASPGEKGECGVPWREGRVW-- 137
++ G AG+ AG G G P T G P + PG+ G G P G +
Sbjct: 165 AVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPS 224
Query: 138 RPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVAS-PGQKGECGVPWREGGVWRPL 196
P + G PG GE G+P G ++ A + PG KG G R G
Sbjct: 225 GPAGKDGESGRPGRPGERGLPGPPG-----IKGPAGIPGFPGMKGHRGFDGRNG------ 273
Query: 197 ERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRG 256
+G +PG KGE G+P G P+ R +PG++G G+P G RG
Sbjct: 274 -EKGETGAPGLKGENGLPGENGAP-GPMGPR---GAPGERGRPGLPGAAG-------ARG 321
Query: 257 SVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASVAS 316
+ + G G+ G P G P SPG KGE G P S +
Sbjct: 322 NDGARGSDGQPGPPGPPGTAGFP-------GSPGAKGEVG----------PAGSPGSNGA 364
Query: 317 PGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECG 352
PG++GE G P G P G SPG KGE G
Sbjct: 365 PGQRGEPG-PQGHAGAQGPPGPPGINGSPGGKGEMG 399
Score = 77.0 bits (188), Expect = 3e-14
Identities = 93/333 (27%), Positives = 113/333 (33%), Gaps = 51/333 (15%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
P P P+ ++ G G AAG G G+P G P S SPG+ G G
Sbjct: 850 PAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPS-GSPGKDGPPGPA 908
Query: 131 WREGRVWRP--LDRRGSVASPGEKGECGVPWREG--------------GVWRPLERRASV 174
G P +G PGEKG G G G+ P
Sbjct: 909 GNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPR 968
Query: 175 ASPGQ---KGECGVPWREG-----GVWRPLERRGSVASPGEKGECGVPWREGRVWRP--- 223
SPG KGE G P G G P G + GE G G P +G R
Sbjct: 969 GSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSP 1028
Query: 224 --LERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEG--GVWRP 279
R SPG G G P GPV P + G G G G P G G P
Sbjct: 1029 GGKGDRGENGSPGAPGAPGHPGPPGPV-GPAGKSGDRGESGPAGPAGAPGPAGSRGAPGP 1087
Query: 280 LERRASVASPGEKGECGVPWTEG--------GVWRPLERRASVASPGEK------GECGV 325
R GE+G G+ G G P ++ ++ SPG G G
Sbjct: 1088 QGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGP 1147
Query: 326 PWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
P ++G P G + PG +G G R EG
Sbjct: 1148 PGKDGTSGHP----GPIGPPGPRGNRGERGSEG 1176
Score = 69.3 bits (168), Expect = 6e-12
Identities = 66/222 (29%), Positives = 82/222 (36%), Gaps = 25/222 (11%)
Query: 68 SAKPGS--------VPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVA 119
S KPG+ P P+ L + G AG G G G+P +G +R +
Sbjct: 980 SGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGEN-G 1038
Query: 120 SPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASP 177
SPG G G P G V P + G G G G P G G P R
Sbjct: 1039 SPGAPGAPGHPGPPGPVG-PAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGET 1097
Query: 178 GQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKG 237
G++G G+ G P G+ SPG G+ G G P R V G G
Sbjct: 1098 GERGAAGIKGHRGFPGNP----GAPGSPGPAGQQGAIGSPG----PAGPRGPVGPSGPPG 1149
Query: 238 ECGVPWREGPVWRPLER-----RGSVASPGEKGECGVPWTEG 274
+ G GP+ P R RGS SPG G+ G P G
Sbjct: 1150 KDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPG 1191
Score = 65.1 bits (157), Expect = 1e-10
Identities = 70/238 (29%), Positives = 86/238 (36%), Gaps = 27/238 (11%)
Query: 138 RPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGV----PWREGGVW 193
RP + +G G+ G G+P R G P + S SPG G C P +
Sbjct: 97 RPPNGQGPQGPKGDPGPPGIPGRNGDPGIP-GQPGSPGSPGPPGICESCPTGPQNYSPQY 155
Query: 194 RPLERRGSVA------SPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGP 247
+ + VA PG G G P G P S SPG +G G P + GP
Sbjct: 156 DSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHP----GSPGSPGYQGPPGEPGQAGP 211
Query: 248 VWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEG----- 302
P G + G G G G RP E R PG KG G+P G
Sbjct: 212 SGPP----GPPGAIGPSGPAGKDGESGRPGRPGE-RGLPGPPGIKGPAGIPGFPGMKGHR 266
Query: 303 GVWRPLERRASVASPGEKGECGVPWREG--GVWRPLDRRGSVASPGEKGECGVRWREG 358
G + +PG KGE G+P G G P G PG G G R +G
Sbjct: 267 GFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDG 324
Score = 47.0 bits (110), Expect = 3e-05
Identities = 44/141 (31%), Positives = 51/141 (36%), Gaps = 19/141 (13%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
P P+ R GE G AAG KG G P G + SPG G+ G G
Sbjct: 1085 PGPQGPRGDKGETGERGAAGIKGHRGFPGNPG----------APGSPGPAGQQGAIGSPG 1134
Query: 135 RVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLER-----RASVASPGQKGECGVPWRE 189
P RG V G G+ G G + P R R S SPG G+ G P
Sbjct: 1135 ----PAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPP 1190
Query: 190 GGVWRPLERRGSVASPGEKGE 210
G G+ A G GE
Sbjct: 1191 GAPGPCCGGVGAAAIAGIGGE 1211
>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
Length = 1745
Score = 99.8 bits (247), Expect = 4e-21
Identities = 90/285 (31%), Positives = 118/285 (41%), Gaps = 15/285 (5%)
Query: 68 SAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGEC 127
SA P P PR ++ G G GEKGE G P +G V + + +PG +GE
Sbjct: 702 SAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGD-QGKPGAPGPRGED 760
Query: 128 GVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPW 187
G +G+ + G S GEKG+ GVP G RP + S+ PG G G
Sbjct: 761 GPEGPKGQAGQ-AGEEGPPGSAGEKGKLGVPGLPGYPGRP-GPKGSIGFPGPLGPIGEKG 818
Query: 188 REGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGP 247
+ G +P G PG +GE G P G+ P +PG GE G+P +GP
Sbjct: 819 KSGKTGQP-GLEGERGPPGSRGERGQPGATGQP-GPKGDVGQDGAPGIPGEKGLPGLQGP 876
Query: 248 VWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRP 307
P G PG +G+ G P G L + PG G G P + G P
Sbjct: 877 PGFP----GPKGPPGHQGKDGRP-GHPGQRGELGFQGQTGPPGPAGVLG-PQGKTGEVGP 930
Query: 308 LERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECG 352
L R PG GE G+P EG +G + PG G+ G
Sbjct: 931 LGERGPPGPPGPPGEQGLPGLEGRE----GAKGELGPPGPLGKEG 971
Score = 91.3 bits (225), Expect = 1e-18
Identities = 91/294 (30%), Positives = 114/294 (38%), Gaps = 23/294 (7%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLE--------RRASVASPGEKGE 126
P PR L G G + G G G P +G V P E S PG +G
Sbjct: 598 PGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGL 657
Query: 127 CGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVP 186
G P +G P G PG G G P EG P + + PG G G P
Sbjct: 658 IGTPGEKG----PPGNPGIPGLPGSDGPLGHPGHEG----PTGEKGAQGPPGSAGPPGYP 709
Query: 187 WREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREG 246
GV RG GEKGE G P +G V + + +PG +GE G +G
Sbjct: 710 GPR-GVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGD-QGKPGAPGPRGEDGPEGPKG 767
Query: 247 PVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWR 306
+ E G S GEKG+ GVP G RP + S+ PG G G G +
Sbjct: 768 QAGQAGE-EGPPGSAGEKGKLGVPGLPGYPGRP-GPKGSIGFPGPLGPIGEKGKSGKTGQ 825
Query: 307 PLERRASVASPGEKGECGVPWREG--GVWRPLDRRGSVASPGEKGECGVRWREG 358
P PG +GE G P G G + + G+ PGEKG G++ G
Sbjct: 826 P-GLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPG 878
Score = 88.2 bits (217), Expect = 1e-17
Identities = 91/298 (30%), Positives = 116/298 (38%), Gaps = 30/298 (10%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVAS--PGEKGECG 128
PG V P + GE G + G G GIP +G + + S A+ PG+KG G
Sbjct: 1192 PGGVGQPGAVGE-KGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPG 1250
Query: 129 VPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWR 188
+G V P G + PG+ G G+ G P V PG G G P
Sbjct: 1251 EDGAKGSVG-PTGLPGDLGPPGDPGVSGIDGSPGEKGDP----GDVGGPGPPGASGEPGA 1305
Query: 189 EG--GVWRPLERRGSVASPGEKGECGVPWREGRVWR--PLERRASVASPGQKGECGVPWR 244
G G P G GEKG G P +G R P+ R G +G G+P
Sbjct: 1306 PGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIP-- 1363
Query: 245 EGPVWRP--LERRGSVASPGEKGECGVPWTEGGVWRPLERR--------ASVASPGEKGE 294
GPV P L G + PG G G+P +G E+ GEKG+
Sbjct: 1364 -GPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGD 1422
Query: 295 CGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECG 352
G+P +G P + PG G G P G V PL ++GS SPG G G
Sbjct: 1423 QGLPGVQG----PPGPKGDPGPPGPIGSLGHPGPPG-VAGPLGQKGSKGSPGSMGPRG 1475
Score = 82.4 bits (202), Expect = 6e-16
Identities = 83/285 (29%), Positives = 106/285 (37%), Gaps = 40/285 (14%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWR--PLERRASVASPGEKGECGVPWREGRVWRP--L 140
GE G G G G+ +G+ PL R PG GE G+P EGR L
Sbjct: 902 GELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGEL 961
Query: 141 DRRGSVASPGEKGECGVPWREGGVWRP--LERRASVASPGQKGECGVPWREGGVWRPLER 198
G + G G G P +GG P + PG G G P G PL
Sbjct: 962 GPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERG----PLGP 1017
Query: 199 RGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSV 258
G + PG+ G G G+ ER PG G+ G+P GP+ P G
Sbjct: 1018 AGGIGLPGQSGSEGPVGPAGKKGSRGER----GPPGPTGKDGIPGPLGPLGPP-GAAGPS 1072
Query: 259 ASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASVASPG 318
G+KG+ G P +G S G+KG+ G P + G+ P + G
Sbjct: 1073 GEEGDKGDVGAPGHKG-------------SKGDKGDAGPP-GQPGIRGPAGHPGPPGADG 1118
Query: 319 EKGECGVPWREG-----------GVWRPLDRRGSVASPGEKGECG 352
+G G P G GV P +G PGEKGE G
Sbjct: 1119 AQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVG 1163
Score = 80.5 bits (197), Expect = 2e-15
Identities = 85/309 (27%), Positives = 108/309 (34%), Gaps = 29/309 (9%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
P P P G G G+KG+ G+ G + P + PGEKGE G
Sbjct: 1107 PAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPP-GLQGLPGPPGEKGEVGDV 1165
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRP-----LERRASVASPGQKGECGV 185
G P G G G G P GGV +P R PG G G+
Sbjct: 1166 GSMG----PHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGI 1221
Query: 186 PWREGGVWRPLER--RGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPW 243
P +G + + G+ PG+KG G +G V P + PG G G+
Sbjct: 1222 PGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSV-GPTGLPGDLGPPGDPGVSGIDG 1280
Query: 244 REGPVWRPLERRGSVASPGEKGECGVPWTEG--GVWRPLERRASVASPGEKGECGVPWTE 301
G P G V PG G G P G G P GEKG G P +
Sbjct: 1281 SPGEKGDP----GDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPD 1336
Query: 302 G--GVWRPLERRASVASPGEKGECGVPWREG--------GVWRPLDRRGSVASPGEKGEC 351
G G P+ R G +G G+P G G P G PG KG+
Sbjct: 1337 GPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDT 1396
Query: 352 GVRWREGRV 360
G + +G +
Sbjct: 1397 GPKGEKGHI 1405
Score = 79.7 bits (195), Expect = 4e-15
Identities = 83/304 (27%), Positives = 110/304 (36%), Gaps = 54/304 (17%)
Query: 74 VPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWRE 133
+P P G AG S G+KG+ G P +G S G+KG+ G P +
Sbjct: 1056 IPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKG-------------SKGDKGDAGPPGQP 1102
Query: 134 GRVWRPLDRRGSVASPGEKGECGVPWREG-----------GVWRPLERRASVASPGQKGE 182
G + P G + G +G G P G GV P + PG+KGE
Sbjct: 1103 G-IRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGE 1161
Query: 183 CG-----VPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKG 237
G P G P GS +PG G G P G R PG G
Sbjct: 1162 VGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGE----KGERGDAGDPGPPG 1217
Query: 238 ECGVPWREGPVWRPLER--RGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGEC 295
G+P +G + + G+ PG+KG G +G V P + PG+ G
Sbjct: 1218 APGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSV-GPTGLPGDLGPPGDPGVS 1276
Query: 296 GVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRW 355
G+ + G P V PG G G P G+ PG++G G
Sbjct: 1277 GIDGSPGEKGDP----GDVGGPGPPGASGEP-------------GAPGPPGKRGPSGHMG 1319
Query: 356 REGR 359
REGR
Sbjct: 1320 REGR 1323
Score = 64.3 bits (155), Expect = 2e-10
Identities = 77/253 (30%), Positives = 96/253 (37%), Gaps = 33/253 (13%)
Query: 68 SAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWR--PLERRASVASPGEKG 125
S +PG+ P P R G G GEKG G P +G R P+ R G +G
Sbjct: 1300 SGEPGA-PGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEG 1358
Query: 126 ECGVPWREGRVWRP--LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGEC 183
G+P G V P L G + PG G G+P +G P + + G G
Sbjct: 1359 LRGIP---GPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDT-GPKGEKGHIGLIGLIGPP 1414
Query: 184 GVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASP-GQKGECGVP 242
G +G P G PG KG+ G P G + P VA P GQKG G P
Sbjct: 1415 GEAGEKGDQGLP----GVQGPPGPKGDPGPPGPIGSLGHP--GPPGVAGPLGQKGSKGSP 1468
Query: 243 WREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEG 302
GP RG G G G P G+ R RR V P +P EG
Sbjct: 1469 GSMGP-------RGDTGPAGPPGPPGAPAELHGLRR---RRRFVPVP-------LPVVEG 1511
Query: 303 GVWRPLERRASVA 315
G+ L S++
Sbjct: 1512 GLEEVLASLTSLS 1524
Score = 61.6 bits (148), Expect = 1e-09
Identities = 65/239 (27%), Positives = 89/239 (37%), Gaps = 41/239 (17%)
Query: 114 RRASVASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRAS 173
++ ++ G G G+ R G V P PG KGE G +G P +
Sbjct: 471 QQTQLSMKGPPGPVGLTGRPGPVGLP-------GHPGLKGEEGAEGPQG----PRGLQGP 519
Query: 174 VASPGQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASP 233
PG+ G+ G P +G P G G++G G+P G
Sbjct: 520 HGPPGRVGKMGRPGADGARGLP----GDTGPKGDRGFDGLPGLPGE-------------K 562
Query: 234 GQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKG 293
GQ+G+ G + GP ER G+ PG G+ G P G L R S G G
Sbjct: 563 GQRGDFGHVGQPGPPGEDGER-GAEGPPGPTGQAGEPGPRG----LLGPRGSPGPTGRPG 617
Query: 294 ECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECG 352
G+ G + +V PGE G G G P +G + +PGEKG G
Sbjct: 618 VTGIDGAPGA-------KGNVGPPGEPGPPGQQGNHGSQGLP-GPQGLIGTPGEKGPPG 668
>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
Length = 1626
Score = 97.4 bits (241), Expect = 2e-20
Identities = 101/306 (33%), Positives = 127/306 (41%), Gaps = 58/306 (18%)
Query: 67 LSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGI------PWTEGQVWRPLERRASVAS 120
L PG V AP + GE G GEKGE G+ P GQ RP + VA
Sbjct: 576 LPGPPGRVGAP----GLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRP--GPSGVAG 629
Query: 121 P-GEKGE---CGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVAS 176
P GEKG+ G P G V + +G +PG +G G P G P+
Sbjct: 630 PQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAP-GPPGARGPIGPEGRDGP 688
Query: 177 P------GQKGECGVPWREG--GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRA 228
P G+KG+ G P G G+ P G PG G G+P G + P
Sbjct: 689 PGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLP---GEIGFP----- 740
Query: 229 SVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVAS 288
PG G G P ++GP P G+ PGE+GE G+P + G+ + +
Sbjct: 741 --GKPGPPGPTGPPGKDGPNGPP-GPPGTKGEPGERGEDGLP-GKPGLRGEIGEQGLAGR 796
Query: 289 PGEKGECGVPWTEG--GVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPG 346
PGEKGE G+P G GV R GEKGE G+P +G DR G
Sbjct: 797 PGEKGEAGLPGAPGFPGV------RGEKGDQGEKGELGLPGLKG------DR-------G 837
Query: 347 EKGECG 352
EKGE G
Sbjct: 838 EKGEAG 843
Score = 90.9 bits (224), Expect = 2e-18
Identities = 86/292 (29%), Positives = 111/292 (38%), Gaps = 37/292 (12%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
P +P L + G G G G G P G++ P PG G G P
Sbjct: 703 PPGIPG---LLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFP-------GKPGPPGPTGPP 752
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
++G P G+ PGE+GE G+P + G + + + PG+KGE G+P G
Sbjct: 753 GKDGPNGPP-GPPGTKGEPGERGEDGLPGKPG-LRGEIGEQGLAGRPGEKGEAGLPGAPG 810
Query: 191 --GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPV 248
GV RG GEKGE G+P +G R G G G+P
Sbjct: 811 FPGV------RGEKGDQGEKGELGLPGLKGD-------RGEKGEAGPAGPPGLPGTTSLF 857
Query: 249 WRPLERRGSVASPGEKGECGVPWTEGGVWRP--LERRASVASPGEKGECGVPWTEGGVWR 306
G GEKG+ G+P G RP L + PG KG+ G G
Sbjct: 858 TPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGN 917
Query: 307 PLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
P +PG G G G V P RG+ GE+GE G EG
Sbjct: 918 P-------GAPGHVGAPGPSGPPGSVGAP-GLRGTPGKDGERGEKGAAGEEG 961
Score = 87.0 bits (214), Expect = 3e-17
Identities = 91/306 (29%), Positives = 118/306 (38%), Gaps = 50/306 (16%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
G AG G+ G G P G V + + +PG +G G P G P+ G
Sbjct: 626 GVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPG-ARGPIGPEG 684
Query: 145 SVASP------GEKGECGVPWREG-----------GVWRPLERRASVASPGQKGECGVPW 187
P G+KG+ G P G GV P SPG GE G P
Sbjct: 685 RDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGP---PGPGGSPGLPGEIGFPG 741
Query: 188 REG-----------GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQK 236
+ G G P G+ PGE+GE G+P + G + + + PG+K
Sbjct: 742 KPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPG-LRGEIGEQGLAGRPGEK 800
Query: 237 GECGVPWREG-PVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGEC 295
GE G+P G P RG GEKGE G+P +G R G G
Sbjct: 801 GEAGLPGAPGFP-----GVRGEKGDQGEKGELGLPGLKGD-------RGEKGEAGPAGPP 848
Query: 296 GVPWTEGGVWRPLERRASVASP-GEKGECGVPWREGGVWRP--LDRRGSVASPGEKGECG 352
G+P T ++ P R P GEKG+ G+P G RP L +G PG KG+ G
Sbjct: 849 GLPGTT-SLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEG 907
Query: 353 VRWREG 358
G
Sbjct: 908 AHGAPG 913
Score = 83.6 bits (205), Expect = 3e-16
Identities = 101/352 (28%), Positives = 132/352 (37%), Gaps = 57/352 (16%)
Query: 50 PREDQMGSVEKLTTSAFLSAK-------PGSVPAPRPLRSIDGEAGHSEAAGEKGECGI- 101
P +Q+G ++ + S K P +P P+ G G GEKG+ GI
Sbjct: 463 PGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIG 522
Query: 102 PWTEGQVWR--------PLERRASVASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKG 153
P+ +G+ P R S GE GE G P G V +G PG G
Sbjct: 523 PFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGM-RGPQGPPGLPGPPG 581
Query: 154 ECGVPWREG-----GVWRPLERRASVASPGQKGECGVPWREG--GVWRPLERRGSV--AS 204
G P +G G R PG+ G+ G R G GV P +G V A
Sbjct: 582 RVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAG 641
Query: 205 P-----------GEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGP--VWRP 251
P G KGE G P G P PG +G G R+GP +
Sbjct: 642 PPGVPGSVVQQEGLKGEQGAPGPRGHQGAP-------GPPGARGPIGPEGRDGPPGLQGL 694
Query: 252 LERRGSVASPGEKGECGVPWTEG--GVWRPLERRASVASPGEKGECGVPWTEG------- 302
++G + PG G G+ G GV P S PGE G G P G
Sbjct: 695 RGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGK 754
Query: 303 -GVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGV 353
G P + PGE+GE G+P + G+ + +G PGEKGE G+
Sbjct: 755 DGPNGPPGPPGTKGEPGERGEDGLPGKP-GLRGEIGEQGLAGRPGEKGEAGL 805
Score = 81.6 bits (200), Expect = 1e-15
Identities = 90/295 (30%), Positives = 117/295 (39%), Gaps = 43/295 (14%)
Query: 74 VPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWRE 133
+P LR GE G + GEKGE G+P G R GEKGE G+P +
Sbjct: 778 LPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFP----GVRGEKGDQGEKGELGLPGLK 833
Query: 134 GRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASP-GQKGECGVPWREGGV 192
G RG G G G+P ++ P R P G+KG+ G+P G
Sbjct: 834 G-------DRGEKGEAGPAGPPGLPGTT-SLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQ 885
Query: 193 WRP--LERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGP--- 247
RP L +G PG KG+ G G + +PG G G P GP
Sbjct: 886 GRPGELGPQGPTGPPGAKGQEGAHGAPG----------AAGNPGAPGHVGAPGPSGPPGS 935
Query: 248 VWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPG-----EKGECGVPWTEG 302
V P RG+ GE+GE G EG P+ R +PG KG+ G P G
Sbjct: 936 VGAP-GLRGTPGKDGERGEKGAAGEEGSP-GPVGPRGDPGAPGLPGPPGKGKDGEPGLRG 993
Query: 303 --GVWRPLERRASVASPGEKGECGVPWREGGVWRPLDR--RGSVASPGEKGECGV 353
G+ PL +A+ C + GG DR G SPG +G+ G+
Sbjct: 994 SPGLPGPLGTKAACGKVRGSENCAL----GGQCVKGDRGAPGIPGSPGSRGDPGI 1044
Score = 81.3 bits (199), Expect = 1e-15
Identities = 100/333 (30%), Positives = 131/333 (39%), Gaps = 70/333 (21%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQ--VWRPL----ERRA--SVASPG 122
PG +P + + + G+ G G+KGE G P G + P ER A V G
Sbjct: 1125 PG-LPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKG 1183
Query: 123 EKGECGVPWREGRVWRP-----------LDRRGSVASPGEKGE---------CGVPWREG 162
++G GVP G P G SPG++G G+P EG
Sbjct: 1184 DQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEG 1243
Query: 163 GVWRPLERRASVASPGQKGECGVPWREGGVWRP--LERRGSVASPGEKGE---CGVPWRE 217
R + PG+ GE G+P EG P G +PG +GE G+P +E
Sbjct: 1244 KEGRD-GKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQE 1302
Query: 218 GRVWRPLERRASVASPGQKGECGVPWREGPVW--RPLERRGSVASPGEKGECGVPWTEG- 274
G PG+ G+ G +GP P + GS SPGE G G P +G
Sbjct: 1303 G-------------LPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGS 1349
Query: 275 -------GVWRPLERRASVASPGEKGECGVPWTEGGVWRPLER--RASVASPGEKGECGV 325
G+ L R PGE GE GVP EG +P E + PG KG+ G
Sbjct: 1350 KGENGSPGLPGFLGPR---GPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGP 1406
Query: 326 PWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
P GG +P G PG KG G+ +G
Sbjct: 1407 P---GGKGQP----GDPGIPGHKGHTGLMGPQG 1432
Score = 80.5 bits (197), Expect = 2e-15
Identities = 103/370 (27%), Positives = 139/370 (37%), Gaps = 87/370 (23%)
Query: 68 SAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRP--LERRASVASPGEKG 125
S PG +P DG+ G G+ GE G+P EG P +PG +G
Sbjct: 1233 SGLPG-IPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRG 1291
Query: 126 ECG---VPWREGRVWR-----------------PLDRRGSVASPGEKGECGVPWREG--- 162
E G +P +EG + P + GS SPGE G G P ++G
Sbjct: 1292 ESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKG 1351
Query: 163 -----GVWRPLERRASVASPGQKGECGVPWREGGVWRPLER--RGSVASPGEKGECGVPW 215
G+ L R PG+ GE GVP +EG +P E +G PG KG+ G P
Sbjct: 1352 ENGSPGLPGFLGPR---GPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPG 1408
Query: 216 REGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEG- 274
+G+ P PG KG G+ GP P E G V PG G+ G P G
Sbjct: 1409 GKGQPGDP-------GIPGHKGHTGL---MGPQGLPGE-NGPVGPPGPPGQPGFPGLRGE 1457
Query: 275 -------------GVWRPLERRASV-----------ASPGEKGECGVPWTEGGVWRPLER 310
+ + LE R + +S G G G P +G L
Sbjct: 1458 SPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDG-----LPG 1512
Query: 311 RAS-VASPGEKGECGVPWREGGVWRPLDRRGSVASP--------GEKGECGVRWREGRVW 361
RA + PG G+ G+ G + P RG+ P GE G G+ + G
Sbjct: 1513 RAGPMGEPGRPGQGGLEGPSGPI-GPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPG 1571
Query: 362 YSLDKRGSVP 371
Y+ D +P
Sbjct: 1572 YAKDGLPGIP 1581
Score = 68.9 bits (167), Expect = 7e-12
Identities = 91/326 (27%), Positives = 122/326 (37%), Gaps = 48/326 (14%)
Query: 67 LSAKPGSVPAPRPLRSIDGEAGHSE--------AAGEKGECGIPWTEGQVWRPLERRASV 118
L PG +P P ++ G+ SE G++G GIP + G P A
Sbjct: 991 LRGSPG-LPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGP 1049
Query: 119 ----------ASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVP-----WREGG 163
SPG +G G P +G P R G+ +PGE+G G P G
Sbjct: 1050 PGPSGPPGDKGSPGSRGLPGFPGPQG----PAGRDGAPGNPGERGPPGKPGLSSLLSPGD 1105
Query: 164 VWRPLERRASVASPGQKGECGVPWREG--GVWRPLERRGSVASPGEKGECGVPWREGRVW 221
+ + + PG G G+P +G GV R G+ GE G G+P G +
Sbjct: 1106 INLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPG-IA 1164
Query: 222 RPL----ERRA--SVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGG 275
P ER A V G +G GVP GP P G + G G G P +G
Sbjct: 1165 GPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNP----GPPGADGIAGAAGPPGIQGS 1220
Query: 276 VWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRP 335
+ G G G+P EG R + PG+ GE G+P EG P
Sbjct: 1221 P----GKEGPPGPQGPSGLPGIPGEEGKEGRD-GKPGPPGEPGKAGEPGLPGPEGARGPP 1275
Query: 336 --LDRRGSVASPGEKGECGVRWREGR 359
G +PG +GE G G+
Sbjct: 1276 GFKGHTGDSGAPGPRGESGAMGLPGQ 1301
Score = 47.4 bits (111), Expect = 2e-05
Identities = 51/162 (31%), Positives = 63/162 (38%), Gaps = 49/162 (30%)
Query: 206 GEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKG 265
GEKGE GV G PG KG+ G GPV G+ GEKG
Sbjct: 481 GEKGEMGVAGPMGL-------------PGPKGDIGAI---GPV-------GAPGPKGEKG 517
Query: 266 ECGV-PWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECG 324
+ G+ P+ +G GEKG G+P G R PGE GE G
Sbjct: 518 DVGIGPFGQG-------------EKGEKGSLGLPGPPGRDGSKGMR----GEPGELGEPG 560
Query: 325 VPWREG--------GVWRPLDRRGSVASPGEKGECGVRWREG 358
+P G G+ P R G+ GE+GE G R +G
Sbjct: 561 LPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKG 602
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 97.1 bits (240), Expect = 2e-20
Identities = 105/344 (30%), Positives = 135/344 (39%), Gaps = 50/344 (14%)
Query: 48 AQPREDQMGSV-EKLTTSAFLSAKPGSVP--APRPLRSIDGEAGHSEAAGEKGECGIPWT 104
++P QM + EK + + PGSV PR + + G+ G + G GE G P
Sbjct: 188 SRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGP 247
Query: 105 EGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREG-- 162
G P+ R PG+ GE G P R G G SPG +G G P G
Sbjct: 248 MG----PIGSRGPEGPPGKPGEDGEPGRNGNPGEV----GFAGSPGARGFPGAPGLPGLK 299
Query: 163 ------GVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVA---------SPGE 207
G+ P + V +PG KGE G P G PL RG +PG+
Sbjct: 300 GHRGHKGLEGP---KGEVGAPGSKGEAG-PTGPMGAMGPLGPRGMPGERGRLGPQGAPGQ 355
Query: 208 KGECGVPWREGRVWRPLERRASVA---SPGQKGECGVPWREGPVWRPLERRGSVASPGEK 264
+G G+P + G + PL S +PG KGE G GP P +RG PG
Sbjct: 356 RGAHGMPGKPGPMG-PLGIPGSSGFPGNPGMKGEAGPTGARGPEG-PQGQRGETGPPGPV 413
Query: 265 GECGVPWTEG-----GVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASVASPGE 319
G G+P G G P + PG G G P +G P R PG
Sbjct: 414 GSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTG-PQGIRGQPGDPGV 472
Query: 320 ---KGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREGRV 360
KGE G G P +G + PGE+G+ G R G V
Sbjct: 473 PGFKGEAGPKGEPG----PHGIQGPIGPPGEEGKRGPRGDPGTV 512
Score = 93.2 bits (230), Expect = 4e-19
Identities = 94/306 (30%), Positives = 121/306 (39%), Gaps = 46/306 (15%)
Query: 68 SAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWR-----PLERRASVASPG 122
SA P P P+ G G G+ G+ G+P +G+ P + + PG
Sbjct: 445 SAGPPGSPGPQ------GSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPG 498
Query: 123 EKGECGVPWREGRVWRP--LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQK 180
E+G+ G G V P + RG+ + G G G+P +G R V S G K
Sbjct: 499 EEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGE----RGPVGSSGPK 554
Query: 181 GECGVPWREGGVWRPLERRGSVASPGEKGE------CGVPWREGRVWRPLERRASVASPG 234
G G P R G P RG +PG +G G P +GR P S+ G
Sbjct: 555 GSQGDPGRPGEPGLP-GARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPP----GSIGIRG 609
Query: 235 QKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRAS--VASPGEK 292
Q G G+P +G G PGE G GVP G + E S V PG
Sbjct: 610 QPGSMGLPGPKGS-------SGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLA 662
Query: 293 GECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREG-----GVWRPLDRRGSVASPGE 347
GE G E G P + PG GE G P +G G PL RG +PGE
Sbjct: 663 GERG----EQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGE 718
Query: 348 KGECGV 353
+GE G+
Sbjct: 719 RGEPGI 724
Score = 91.3 bits (225), Expect = 1e-18
Identities = 96/306 (31%), Positives = 122/306 (39%), Gaps = 36/306 (11%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRP----LERRASVASP-GEKG 125
PGS P P + GE G ++G KG G P G+ P L V P G+ G
Sbjct: 530 PGSDGLPGP-KGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLG 588
Query: 126 ECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGV 185
G P +GR P GS+ G+ G G+P +G P PG+ G GV
Sbjct: 589 PLGAPGEDGRPGPP----GSIGIRGQPGSMGLPGPKGSSGDP-------GKPGEAGNAGV 637
Query: 186 PWREGGVWRPLE--RRGSVASPG---EKGECGVPWREGRVWRPLERRASVASPGQKGECG 240
P + G + E G V PG E+GE G P G P G+ G+ G
Sbjct: 638 PGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLP-GPPGPPGEGGKPGDQG 696
Query: 241 VPWREGPVWRPLERRGSVASPGEKGECGVPWTEG-----GVWRPLERRASVASPGEKGEC 295
VP G V PL RG +PGE+GE G+ G G P + S G G+
Sbjct: 697 VPGDPGAVG-PLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDT 755
Query: 296 GVPWTEG-----GVWRPLERRASVASPGEKGECGVPWREG--GVWRPLDRRGSVASPGEK 348
G P +G G+ + GEKG G +G G+ PL G GEK
Sbjct: 756 GPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEK 815
Query: 349 GECGVR 354
GE G R
Sbjct: 816 GEPGPR 821
Score = 88.6 bits (218), Expect = 9e-18
Identities = 105/365 (28%), Positives = 133/365 (36%), Gaps = 77/365 (21%)
Query: 68 SAKPGS--VPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQ--------VWRPL----- 112
+ PG+ P L + G GH G KGE G P ++G+ PL
Sbjct: 281 AGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGM 340
Query: 113 ----ERRASVASPGEKGECGVPWREGRVWRPLDRRGS---VASPGEKGECGVPWREGGVW 165
R +PG++G G+P + G + PL GS +PG KGE G P G
Sbjct: 341 PGERGRLGPQGAPGQRGAHGMPGKPGPM-GPLGIPGSSGFPGNPGMKGEAG-PTGARGPE 398
Query: 166 RPLERRASVASPGQKGECGVPWREG-----GVWRPLERRGSVASPGEKGECGVPWREGRV 220
P +R PG G G+P G G P G+ PG G G P +G
Sbjct: 399 GPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGST 458
Query: 221 WRPLERRASVASP---------GQKGECGVPWREGPVWRPLER--------RGSVASPGE 263
P R P G KGE G +GP+ P E G+V PG
Sbjct: 459 -GPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGP 517
Query: 264 KGECGVPWTEG-----GVWRPL----ER--------RASVASPGEKGECGVPWTEG---- 302
GE G P G G+ P ER + S PG GE G+P G
Sbjct: 518 VGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGN 577
Query: 303 -GVWRPLERRASVASPGEKGECGVPWREG--------GVWRPLDRRGSVASPGEKGECGV 353
GV P + + +PGE G G P G G+ P G PGE G GV
Sbjct: 578 PGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGV 637
Query: 354 RWREG 358
+ G
Sbjct: 638 PGQRG 642
Score = 88.2 bits (217), Expect = 1e-17
Identities = 98/332 (29%), Positives = 122/332 (36%), Gaps = 41/332 (12%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
P PR L G G+ + GE G G G + PG KGE G P ++G
Sbjct: 818 PGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGP-------QGPDGQPGVKGEPGEPGQKG 870
Query: 135 RVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG--GV 192
P +G SPG G GVP +GG A+ PG G G P G G
Sbjct: 871 DAGSP-GPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGAT-GFPGSAGRVGPPGPAGAPGP 928
Query: 193 WRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRP- 251
PL G PG +G+ P GRV PG KG+ G + GP P
Sbjct: 929 AGPLGEPGKEGPPGLRGD---PGSHGRV-GDRGPAGPPGGPGDKGDPGEDGQPGPDGPPG 984
Query: 252 ----LERRGSVASPGEKGECGVPWTEGGVWRP--LERRASVASPGEKGECGVPWTEGGVW 305
+RG V PG++GE G+P G P + + G G G P + G V
Sbjct: 985 PAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVG 1044
Query: 306 RPLERRASVASPGEKGECGVPWREGGVWRPLDR--------RGSVASPGEKGECGVRWRE 357
P G G G P R+G V DR GS +PG G G
Sbjct: 1045 EP-------GPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDA 1097
Query: 358 GRVWYSLDKRGSVPAALASQRHALLALPQPQG 389
G+ + P A +R LP PQG
Sbjct: 1098 GQRGDPGSRGPIGPPGRAGKR----GLPGPQG 1125
Score = 79.0 bits (193), Expect = 7e-15
Identities = 90/311 (28%), Positives = 109/311 (35%), Gaps = 47/311 (15%)
Query: 70 KPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGV 129
+PG VP +R G AG + G +GE G G P + PG G+ G
Sbjct: 117 EPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPG----PRGPQGIDGEPGVPGQPGA 172
Query: 130 PWREGRVWRP----LDRRGSVASPGEKGECGVPWREG---GVWRPLERRASVASPGQKGE 182
P G P L R S G + G+ + G G P+ R GQ+G
Sbjct: 173 PGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGG 232
Query: 183 CGVPWREG-----GVWRPLERRGSVASPGEKGECGVPWREGR------VWRPLER--RAS 229
G G G P+ RG PG+ GE G P R G P R +
Sbjct: 233 AGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGA 292
Query: 230 VASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASP 289
PG KG G EGP +G V +PG KGE G P G PL R
Sbjct: 293 PGLPGLKGHRGHKGLEGP-------KGEVGAPGSKGEAG-PTGPMGAMGPLGPRGMPGER 344
Query: 290 GEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREG--------GVWRPLDRRGS 341
G G G P G P PG G G+P G G P RG
Sbjct: 345 GRLGPQGAPGQRGAHGMP-------GKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGP 397
Query: 342 VASPGEKGECG 352
G++GE G
Sbjct: 398 EGPQGQRGETG 408
Score = 79.0 bits (193), Expect = 7e-15
Identities = 82/282 (29%), Positives = 106/282 (37%), Gaps = 43/282 (15%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
G+ G G G G T GQ R V PG++GE G+P G P G
Sbjct: 969 GDPGEDGQPGPDGPPGPAGTTGQ-------RGIVGMPGQRGERGMPGLPGPAGTP----G 1017
Query: 145 SVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECG---VPWREGGVWR------- 194
V G G+ G P G P V PG +G G P R+G V
Sbjct: 1018 KVGPTGATGDKGPPGPVG----PPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDP 1073
Query: 195 -PLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLE 253
P GS +PG G G P G+ P R + PG+ G+ G+P +GP
Sbjct: 1074 GPAGLPGSQGAPGTPGPVGAPGDAGQRGDP-GSRGPIGPPGRAGKRGLPGPQGP------ 1126
Query: 254 RRGSVASPGEKGECGVPWTEGGVWRPLERRASVASP-GEKGECGVPWTEG--GVWRPLER 310
RG G++G+ G G + L+ P GE+G G+P G G P+
Sbjct: 1127 -RGDKGDHGDRGDRGQKGHRG--FTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGP 1183
Query: 311 RASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECG 352
+PG G G P GV + G PGE G G
Sbjct: 1184 SGKEGNPGPLGPIGPP----GVRGSVGEAGPEGPPGEPGPPG 1221
Score = 42.0 bits (97), Expect = 0.001
Identities = 54/171 (31%), Positives = 65/171 (38%), Gaps = 28/171 (16%)
Query: 206 GEKGECG-VPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLER--RGSVASPG 262
G+KGE G VP G RP PG +G G GP RP R +G PG
Sbjct: 113 GQKGEPGLVPVVTGIRGRP----GPAGPPGSQGPRG---ERGPKGRPGPRGPQGIDGEPG 165
Query: 263 EKGECGVPWTEG--------GVWRPLERRASVASPGEKGECG-----VPWTEGGVWRPLE 309
G+ G P G G+ RP A +A EK G +P + G V P
Sbjct: 166 VPGQPGAPGPPGHPSHPGPDGLSRPFS--AQMAGLDEKSGLGSQVGLMPGSVGPVG-PRG 222
Query: 310 RRASVASPGEKGECGVPWREG--GVWRPLDRRGSVASPGEKGECGVRWREG 358
+ G G G P G G P+ RG PG+ GE G R G
Sbjct: 223 PQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNG 273
Score = 35.4 bits (80), Expect = 0.088
Identities = 33/117 (28%), Positives = 43/117 (36%), Gaps = 15/117 (12%)
Query: 74 VPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWRE 133
+P P+ R G+ G G+KG G +G P GE+G G+P
Sbjct: 1120 LPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPP-------GPNGEQGSAGIP--- 1169
Query: 134 GRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
P RG G G+ G P G + P R SV G +G G P G
Sbjct: 1170 ----GPFGPRGPPGPVGPSGKEGNPGPLGPIGPP-GVRGSVGEAGPEGPPGEPGPPG 1221
>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
Length = 1669
Score = 95.5 bits (236), Expect = 7e-20
Identities = 94/312 (30%), Positives = 126/312 (40%), Gaps = 59/312 (18%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
G G + G+ G G+P +GQ +P PG KG+ G+ G P +G
Sbjct: 960 GPIGEKGSRGDPGTPGVPGKDGQAGQP-------GQPGPKGDPGISGTPGAPGLP-GPKG 1011
Query: 145 SVA------SPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLER 198
SV +PGEKG G+P +G P ++ A G+KG+ G P G+ P R
Sbjct: 1012 SVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAK----GEKGQAGPP----GIGIPGLR 1063
Query: 199 RGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSV 258
GEKG+ G+ G E+ S+ PG G G+ G V P GS
Sbjct: 1064 -------GEKGDQGIAGFPGSPGEKGEK-GSIGIPGMPGSPGLKGSPGSVGYP----GSP 1111
Query: 259 ASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASVASPG 318
PGEKG+ G+P +G PG KGE G+P T G G
Sbjct: 1112 GLPGEKGDKGLPGLDG-------------IPGVKGEAGLPGTPGPT-------GPAGQKG 1151
Query: 319 EKGECGVPWREGGVWRP-LDRRGSVASPGEKGECGVRWREGRVWYSLDKRGSVPAALASQ 377
E G G+P G P L RG PG KG+ G + G + L +P + Q
Sbjct: 1152 EPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVG--FPGLAGSPGIPGSKGEQ 1209
Query: 378 RHALLALPQPQG 389
+ P PQG
Sbjct: 1210 --GFMGPPGPQG 1219
Score = 94.4 bits (233), Expect = 2e-19
Identities = 90/292 (30%), Positives = 124/292 (42%), Gaps = 49/292 (16%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
G G G KGE G+ T GQ P A PGEKG+ G P G RG
Sbjct: 867 GAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAP-GLPGEKGDHGFPGSSGP-------RG 918
Query: 145 SVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVAS 204
G+KG+ G+P + G +++ + GQKG+ G E G P+ +GS
Sbjct: 919 DPGLKGDKGDVGLPGKPGS----MDKVDMGSMKGQKGDQG----EKGQIGPIGEKGSRGD 970
Query: 205 PGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSV------ 258
PG GVP ++G+ +P PG KG+ G+ G P +GSV
Sbjct: 971 PGTP---GVPGKDGQAGQP-------GQPGPKGDPGISGTPGAPGLP-GPKGSVGGMGLP 1019
Query: 259 ASPGEKGECGVPWTEGGVWRPLERRA----------SVASPGEKGECGVPWTEGGVWRPL 308
+PGEKG G+P +G P ++ A + PG +GE G G P
Sbjct: 1020 GTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPG 1079
Query: 309 ER--RASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
E+ + S+ PG G G+ G V P GS PGEKG+ G+ +G
Sbjct: 1080 EKGEKGSIGIPGMPGSPGLKGSPGSVGYP----GSPGLPGEKGDKGLPGLDG 1127
Score = 92.0 bits (227), Expect = 8e-19
Identities = 91/295 (30%), Positives = 116/295 (39%), Gaps = 55/295 (18%)
Query: 84 DGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASV------ASPGEKGECGVPWREGRVW 137
DG+AG G KG+ GI T G P + SV +PGEKG G+P +G
Sbjct: 980 DGQAGQPGQPGPKGDPGISGTPGAPGLP-GPKGSVGGMGLPGTPGEKGVPGIPGPQGSPG 1038
Query: 138 RPLDR-----RGSVASP--------GEKGECGVPWREGGVWRPLERRASVASPGQKGECG 184
P D+ +G P GEKG+ G+ G E + S+ PG G G
Sbjct: 1039 LPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGE-KGSIGIPGMPGSPG 1097
Query: 185 VPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWR 244
+ G V P GS PGEKG+ G+P +G PG KGE G+P
Sbjct: 1098 LKGSPGSVGYP----GSPGLPGEKGDKGLPGLDG-------------IPGVKGEAGLPGT 1140
Query: 245 EGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRP-LERRASVASP------GEKGECGV 297
GP G GE G G+P + G P L R P G KGE G
Sbjct: 1141 PGPT-------GPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGF 1193
Query: 298 PWTEG--GVWRPLERRASVASPGEKGECGVPWREGGVWR-PLDRRGSVASPGEKG 349
P G G+ + + PG +G+ G+P G P RG PG G
Sbjct: 1194 PGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPG 1248
Score = 85.9 bits (211), Expect = 6e-17
Identities = 83/291 (28%), Positives = 116/291 (39%), Gaps = 52/291 (17%)
Query: 67 LSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGE 126
+ PG + P + GE G G G G+P +G V P PG G
Sbjct: 155 MKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPP----GFTGPPGPPGP 210
Query: 127 CGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVP 186
G P +G++ L +G G++G G P G ++ + A+ G+KG+ G P
Sbjct: 211 PGPPGEKGQM--GLSFQGPKGDKGDQGVSGPPGVPGQA--QVQEKGDFATKGEKGQKGEP 266
Query: 187 WREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLER--RASVASPGQKGECGVPWR 244
+G + GEKGE G P G+ + ++ + S PG+ G G+ R
Sbjct: 267 GFQG-----------MPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGR 315
Query: 245 EGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGV 304
+GP GEKGE G P G V GEKGE G P T G
Sbjct: 316 QGP-------------QGEKGEAGPPGPPGIV-------IGTGPLGEKGERGYPGTPG-- 353
Query: 305 WRPLERRASVASPGEKGECGVPWREGGVWRPL-DRRGSVASPGEKGECGVR 354
PG KG G+P + G P+ + G+ PGE+GE G R
Sbjct: 354 --------PRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDR 396
Score = 80.1 bits (196), Expect = 3e-15
Identities = 85/289 (29%), Positives = 114/289 (39%), Gaps = 53/289 (18%)
Query: 80 LRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRP 139
L+ + G G GEKG G+P G+ ++ PG +G G P G
Sbjct: 741 LKGLPGLPGIPGTPGEKGSIGVPGVPGE-------HGAIGPPGLQGIRGEPGPPGLP--- 790
Query: 140 LDRRGSVASPGEKG--ECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG-GVWRPL 196
GSV SPG G G GG P PG KGE G P G + P
Sbjct: 791 ----GSVGSPGVPGIGPPGARGPPGGQGPP----GLSGPPGIKGEKGFPGFPGLDMPGPK 842
Query: 197 ERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGV------PWREGPVWR 250
+G+ PG G+ G+P G+ P PG KGE GV P GPV
Sbjct: 843 GDKGAQGLPGITGQSGLPGLPGQQGAP----GIPGFPGSKGEMGVMGTPGQPGSPGPV-- 896
Query: 251 PLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLER 310
G+ PGEKG+ G P + G R G+KG+ G+P G +++
Sbjct: 897 -----GAPGLPGEKGDHGFPGSSG-------PRGDPGLKGDKGDVGLPGKPGS----MDK 940
Query: 311 RASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREGR 359
+ G+KG+ G E G P+ +GS PG G G + G+
Sbjct: 941 VDMGSMKGQKGDQG----EKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQ 985
Score = 79.0 bits (193), Expect = 7e-15
Identities = 94/316 (29%), Positives = 120/316 (37%), Gaps = 62/316 (19%)
Query: 70 KPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGV 129
+PG P PR DG+ G + G GE G P G+ GEKGE G
Sbjct: 279 EPGK-PGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQ----------GPQGEKGEAGP 327
Query: 130 PWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWRE 189
P G V G + GE+G G P G PG KG G+P +
Sbjct: 328 PGPPGIVIGT----GPLGEKGERGYPGTPGPRG-------------EPGPKGFPGLPGQP 370
Query: 190 GGVWRPLE-RRGSVASPGEKGECG--------VPWREGRVWRPLERRASVASPGQKG--- 237
G P+ + G+ PGE+GE G +P GR P S PGQ G
Sbjct: 371 GPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLP-GPPGSPGPPGQPGYTN 429
Query: 238 ---EC--GVPWREGPVWRPLERR--GSVASPGEKGE----CGVPWTEG--GVWRPLERRA 284
EC G P +GP P + G + G+KGE C + G G P
Sbjct: 430 GIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIG 489
Query: 285 SVASPGEKGECGVPWTEG--GVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSV 342
PG KG+ G+P +G GV P + PG KGE G + L +G
Sbjct: 490 FPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGE------PGEFYFDLRLKGDK 543
Query: 343 ASPGEKGECGVRWREG 358
PG G+ G+ R G
Sbjct: 544 GDPGFPGQPGMTGRAG 559
Score = 79.0 bits (193), Expect = 7e-15
Identities = 85/289 (29%), Positives = 110/289 (38%), Gaps = 49/289 (16%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
PG P + R + G G + G +G G+ G P E + G+KG+ G P
Sbjct: 491 PGQ-PGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFP 549
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREG-----GVWRPLERRASVASPGQKGECGV 185
+ G G SPG G G+P +G G+ V PG +G+ G
Sbjct: 550 GQPGMT-------GRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGP 602
Query: 186 PWREG-GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWR 244
P G G P+ +G PG G G+P +G E V PG G G+P
Sbjct: 603 PGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKG------EPGKIVPLPGPPGAEGLP-- 654
Query: 245 EGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGV 304
GS PG +G+ G P T G RP PGEKG G P G
Sbjct: 655 -----------GSPGFPGPQGDRGFPGTPG---RP-------GLPGEKGAVGQPGI--GF 691
Query: 305 WRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGV 353
P + PG+ G G P R G P G+ G+KGE GV
Sbjct: 692 PGPPGPKGVDGLPGDMGPPGTPGRPGFNGLP----GNPGVQGQKGEPGV 736
Score = 78.6 bits (192), Expect = 9e-15
Identities = 79/277 (28%), Positives = 109/277 (39%), Gaps = 30/277 (10%)
Query: 84 DGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRR 143
+G G G+ GE G+P T+G P + PG G G+P ++G P
Sbjct: 69 EGPQGPPGQKGDTGEPGLPGTKGTRGPP----GASGYPGNPGLPGIPGQDGPPGPP-GIP 123
Query: 144 GSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVA 203
G + GE+G G P G P PG KG+ G RG
Sbjct: 124 GCNGTKGERGPLGPPGLPGFAGNP----GPPGLPGMKGDPGEILGHVPGMLLKGERGFPG 179
Query: 204 SPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGE 263
PG G G+P +G V P PG G G P +G + L +G G+
Sbjct: 180 IPGTPGPPGLPGLQGPVGPP----GFTGPPGPPGPPGPPGEKGQM--GLSFQGPKGDKGD 233
Query: 264 KGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGEC 323
+G G P G ++ + A+ GEKG+ G P +G + GEKGE
Sbjct: 234 QGVSGPPGVPGQA--QVQEKGDFATKGEKGQKGEPGFQG-----------MPGVGEKGEP 280
Query: 324 GVPWREGGVWRPLDR--RGSVASPGEKGECGVRWREG 358
G P G + D+ +GS PGE G G+ R+G
Sbjct: 281 GKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQG 317
Score = 73.2 bits (178), Expect = 4e-13
Identities = 85/286 (29%), Positives = 108/286 (37%), Gaps = 60/286 (20%)
Query: 81 RSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPL 140
+ I G G GEKG GIP G SPG KG G V P
Sbjct: 1069 QGIAGFPGSPGEKGEKGSIGIPGMPG-------------SPGLKGS------PGSVGYP- 1108
Query: 141 DRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRG 200
GS PGEKG+ G+P +G PG KGE G+P G P ++G
Sbjct: 1109 ---GSPGLPGEKGDKGLPGLDG-------------IPGVKGEAGLPGTPGPT-GPAGQKG 1151
Query: 201 SVAS---PGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLER--R 255
S PG GE G P GR + + G KGE G P G P + +
Sbjct: 1152 EPGSDGIPGSAGEKGEPGLPGRGFPGFP--GAKGDKGSKGEVGFPGLAGSPGIPGSKGEQ 1209
Query: 256 GSVASPGEKGECGVPWTEG-------GVWRPLERRASVASPGEKGECGVPWTEGGVWRPL 308
G + PG +G+ G+P + G G P + PG G G+P +G
Sbjct: 1210 GFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDG------ 1263
Query: 309 ERRASVASPGEKGECGVPWREG--GVWRPLDRRGSVASPGEKGECG 352
+ +PG G GVP +G G GS G KG+ G
Sbjct: 1264 -VKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMG 1308
Score = 72.4 bits (176), Expect = 7e-13
Identities = 92/304 (30%), Positives = 120/304 (39%), Gaps = 45/304 (14%)
Query: 74 VPAPRPLRSIDGEAGHSEAAGEKGE---CGIPWTEGQVWRP-LERRASVASPGEKGECGV 129
+P + + G G + AG+KGE GIP + G+ P L R PG KG+ G
Sbjct: 1128 IPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKG- 1186
Query: 130 PWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRP-LERRASVASPGQKGECGVPWR 188
+G V P GS PG KGE G G +P L A+ G KG+ G +
Sbjct: 1187 --SKGEVGFP-GLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQ 1243
Query: 189 EG--GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLER--------------RASVAS 232
G G+ P+ G G KG+ G P G P + S
Sbjct: 1244 PGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGS 1303
Query: 233 PGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGE- 291
G G GVP +GP P G G++G+ GVP +G P PG
Sbjct: 1304 KGDMGPPGVPGFQGPKGLP----GLQGIKGDQGDQGVPGAKGLPGPP-------GPPGPY 1352
Query: 292 ---KGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEK 348
KGE G+P EG P + PG KG+ GV G+ P G +PG+K
Sbjct: 1353 DIIKGEPGLPGPEG----PPGLKGLQGLPGPKGQQGVTGLV-GIPGPPGIPGFDGAPGQK 1407
Query: 349 GECG 352
GE G
Sbjct: 1408 GEMG 1411
Score = 70.5 bits (171), Expect = 2e-12
Identities = 92/293 (31%), Positives = 107/293 (36%), Gaps = 62/293 (21%)
Query: 71 PGSV--PAPRPLRSIDGEAGHSEAA--GEKGECGIPWTEGQVWRPL---ERRASVASPGE 123
PG V P R G G+ A G+KG+ G P G P E V PG
Sbjct: 588 PGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGP 647
Query: 124 KGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGEC 183
G G+P G DR PG G G+P +G V +P + PG G
Sbjct: 648 PGAEGLPGSPGFPGPQGDR----GFPGTPGRPGLPGEKGAVGQP-----GIGFPGPPGPK 698
Query: 184 GVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPW 243
GV G + P G+ PG G G P +G+ P V PG KG G+P
Sbjct: 699 GVDGLPGDMGPP----GTPGRPGFNGLPGNPGVQGQKGEP-----GVGLPGLKGLPGLP- 748
Query: 244 REGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEG- 302
G +PGEKG GVP GV PGE G G P +G
Sbjct: 749 ------------GIPGTPGEKGSIGVP----GV------------PGEHGAIGPPGLQGI 780
Query: 303 -GVWRPLERRASVASPGEK--GECGVPWREGGVWRPLDRRGSVASPGEKGECG 352
G P SV SPG G G GG P G PG KGE G
Sbjct: 781 RGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPP----GLSGPPGIKGEKG 829
Score = 58.5 bits (140), Expect = 1e-08
Identities = 56/198 (28%), Positives = 78/198 (39%), Gaps = 37/198 (18%)
Query: 178 GQKGECGVPWREG-----GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVAS 232
GQKGE G+P +G G+ P +G G+ GE G+P +G P +
Sbjct: 46 GQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPP----GASGY 101
Query: 233 PGQKGECGVPWREGPVWRP--------LERRGSVASPG------EKGECGVPWTEGGVWR 278
PG G G+P ++GP P RG + PG G G+P +G
Sbjct: 102 PGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGE 161
Query: 279 PLERRASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDR 338
L + GE+G G+P T G PG +G G P G P
Sbjct: 162 ILGHVPGMLLKGERGFPGIPGTPG----------PPGLPGLQGPVGPP----GFTGPPGP 207
Query: 339 RGSVASPGEKGECGVRWR 356
G PGEKG+ G+ ++
Sbjct: 208 PGPPGPPGEKGQMGLSFQ 225
Score = 52.4 bits (124), Expect = 7e-07
Identities = 67/218 (30%), Positives = 84/218 (38%), Gaps = 27/218 (12%)
Query: 67 LSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEG----QVWRPLERRASVA-SP 121
L PG + P L IDG G G G G+P +G Q + + S
Sbjct: 1246 LPGLPGPM-GPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSK 1304
Query: 122 GEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQ-- 179
G+ G GVP +G P G G++G+ GVP +G P PG
Sbjct: 1305 GDMGPPGVPGFQG----PKGLPGLQGIKGDQGDQGVPGAKGLPGPP-------GPPGPYD 1353
Query: 180 --KGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKG 237
KGE G+P EG P +G PG KG+ GV G + P +PGQKG
Sbjct: 1354 IIKGEPGLPGPEG----PPGLKGLQGLPGPKGQQGVTGLVG-IPGPPGIPGFDGAPGQKG 1408
Query: 238 ECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGG 275
E G GP P G PG G G P + G
Sbjct: 1409 EMGPAGPTGPRGFP-GPPGPDGLPGSMGPPGTPSVDHG 1445
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 95.1 bits (235), Expect = 9e-20
Identities = 93/316 (29%), Positives = 126/316 (39%), Gaps = 50/316 (15%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
P P PR ++ DG G GEKGE G P +G + + R + PG +GE G
Sbjct: 785 PIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGD-RGEIGPPGPRGEDGPE 843
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASP------GQKGECG 184
+GR P G + PGEKG+ GVP G R + S+ P G+KG G
Sbjct: 844 GPKGR-GGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQ-GPKGSIGFPGFPGANGEKGGRG 901
Query: 185 VPWREGGVWRPLERRGSVASPGEKGECGVPWR---------EGRVWRPLER-----RASV 230
P + G P +RG GE+G G+ + +G P ER +
Sbjct: 902 TPGKPG----PRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPT 957
Query: 231 ASPGQKGECGVPWREGPVWRPLER-----RGSVASPGEKGECGVPWTEGGVWRPLERRAS 285
PG KG G P ++G P +R +G PG G G P G P+ R
Sbjct: 958 GFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVG-PQGPTGETGPMGERGH 1016
Query: 286 VASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVAS- 344
PG GE G+P G + G+ G G+P ++G P RG
Sbjct: 1017 PGPPGPPGEQGLPGLAG----------KEGTKGDPGPAGLPGKDG----PPGLRGFPGDR 1062
Query: 345 --PGEKGECGVRWREG 358
PG G G++ EG
Sbjct: 1063 GLPGPVGALGLKGNEG 1078
Score = 93.6 bits (231), Expect = 3e-19
Identities = 90/298 (30%), Positives = 117/298 (39%), Gaps = 65/298 (21%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
P P P + +DG+ G G +GE G P +G + PG +G G P
Sbjct: 689 PPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQG-------NPGAQGLPGPQGAIGPP 741
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
+G PL + G PG G G P +EG PG+KG G P +G
Sbjct: 742 GEKG----PLGKPGLPGMPGADGPPGHPGKEG-------------PPGEKGGQGPPGPQG 784
Query: 191 GVWRPLER--------RGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVP 242
+ P R RG + GEKGE G P +G + + R + PG +GE G
Sbjct: 785 PIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGD-RGEIGPPGPRGEDG-- 841
Query: 243 WREGPVWR--PLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWT 300
EGP R P G + PGEKG+ GVP G R G KG G P
Sbjct: 842 -PEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGR----------QGPKGSIGFPGF 890
Query: 301 EGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
G + GEKG G P + G P +RG GE+G G+ + G
Sbjct: 891 PG-------------ANGEKGGRGTPGKPG----PRGQRGPTGPRGERGPRGITGKPG 931
Score = 91.3 bits (225), Expect = 1e-18
Identities = 96/318 (30%), Positives = 125/318 (39%), Gaps = 38/318 (11%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
PG+ P P +I G G G+ G G+P +G P PGEKG G P
Sbjct: 726 PGAQGLPGPQGAI-GPPGEKGPLGKPGLPGMPGADGPPGHP----GKEGPPGEKGGQGPP 780
Query: 131 WREGRVWRPLDR--------RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGE 182
+G + P R RG + GEKGE G P +G + +R + PG +GE
Sbjct: 781 GPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDR-GEIGPPGPRGE 839
Query: 183 CGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPG------QK 236
G P G P G + PGEKG+ GVP G R + S+ PG +K
Sbjct: 840 DG-PEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQ-GPKGSIGFPGFPGANGEK 897
Query: 237 GECGVPWREGPVWR-----PLERRGSVASPGEKGECGVPWTEGGVWRPLER-----RASV 286
G G P + GP + P RG G+ G G +G P ER +
Sbjct: 898 GGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPT 957
Query: 287 ASPGEKGECGVPWTEGGVWRPLER-----RASVASPGEKGECGVPWREGGVWRPLDRRGS 341
PG KG G P +G P +R + PG G G P G P+ RG
Sbjct: 958 GFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVG-PQGPTGETGPMGERGH 1016
Query: 342 VASPGEKGECGVRWREGR 359
PG GE G+ G+
Sbjct: 1017 PGPPGPPGEQGLPGLAGK 1034
Score = 88.6 bits (218), Expect = 9e-18
Identities = 94/305 (30%), Positives = 119/305 (39%), Gaps = 34/305 (11%)
Query: 67 LSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGE 126
L+ +PG V P + GE G G +G G P G+ R R S G +G
Sbjct: 566 LTGRPGPVGPPGS-GGLKGEPGDVGPQGPRGVQGPPGPAGKPGR----RGRAGSDGARGM 620
Query: 127 CGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVP 186
G +G R D G PGEKG G P G P + G+ G G+P
Sbjct: 621 PGQTGPKGD--RGFD--GLAGLPGEKGHRGDPGPSGPPGPPGDD-GERGDDGEVGPRGLP 675
Query: 187 WREG--GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWR 244
G G+ P G PG G G P +G V + PGQ+G G
Sbjct: 676 GEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGP----QGEPGPPGQQGNPGAQGL 731
Query: 245 EGPVWRPLERRGSVASPGEKGECGVPWTEG--GVWRPLERRASVASPGEKGECGVPWTEG 302
GP +G++ PGEKG G P G G P PGEKG G P +G
Sbjct: 732 PGP-------QGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQG 784
Query: 303 GVWRPLER--------RASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVR 354
+ P R R + GEKGE G P +G + DR G + PG +GE G
Sbjct: 785 PIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDR-GEIGPPGPRGEDGPE 843
Query: 355 WREGR 359
+GR
Sbjct: 844 GPKGR 848
Score = 85.1 bits (209), Expect = 1e-16
Identities = 91/301 (30%), Positives = 111/301 (36%), Gaps = 52/301 (17%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWR---PLERRASVASPGEKGECGVPW 131
P P + + G AG G+ G G+P +G P +R PG G G+
Sbjct: 1020 PGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDR----GLPGPVGALGLKG 1075
Query: 132 REGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGG 191
EG P G SPGE+G G G RP PG GE G P E G
Sbjct: 1076 NEGPPGPP----GPAGSPGERGPAGAAGPIGIPGRP----GPQGPPGPAGEKGAPG-EKG 1126
Query: 192 VWRPLER---RGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPV 248
P R +G V PG G G P +G + + PGQKG G +GP
Sbjct: 1127 PQGPAGRDGLQGPVGLPGPAGPVGPPGEDGD-------KGEIGEPGQKGSKGDKGEQGPP 1179
Query: 249 WRPLERRGSVASPGEKGECGVPWTEG-----------------GVWRPLERRASVASPGE 291
P +G + PG G G P G G P+ + PGE
Sbjct: 1180 -GPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGE 1238
Query: 292 KGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGEC 351
KGE G G P R S +PG G G P GG+ P G+V GE GE
Sbjct: 1239 KGETGDVGQMGPPGPPGPRGPS-GAPGADGPQGPP---GGIGNP----GAVGEKGEPGEA 1290
Query: 352 G 352
G
Sbjct: 1291 G 1291
Score = 84.7 bits (208), Expect = 1e-16
Identities = 85/286 (29%), Positives = 105/286 (36%), Gaps = 40/286 (13%)
Query: 81 RSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPL 140
R I G+ G +G G G P G P + PG KG G P ++G P
Sbjct: 924 RGITGKPGPKGNSGGDGPAGPPGERG----PNGPQGPTGFPGPKGPPGPPGKDGLPGHPG 979
Query: 141 DR-----RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRP 195
R +G PG G G P G P+ R PG GE G+P G
Sbjct: 980 QRGETGFQGKTGPPGPPGVVG-PQGPTGETGPMGERGHPGPPGPPGEQGLPGLAG----- 1033
Query: 196 LERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERR 255
+ G+ PG G G G P +R PG G G+ EGP P
Sbjct: 1034 --KEGTKGDPGPAGLPGKDGPPGLRGFPGDR----GLPGPVGALGLKGNEGPPGPP---- 1083
Query: 256 GSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLER---RA 312
G SPGE+G G G RP PG GE G P E G P R +
Sbjct: 1084 GPAGSPGERGPAGAAGPIGIPGRP----GPQGPPGPAGEKGAPG-EKGPQGPAGRDGLQG 1138
Query: 313 SVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
V PG G G P +G +G + PG+KG G + +G
Sbjct: 1139 PVGLPGPAGPVGPPGEDGD-------KGEIGEPGQKGSKGDKGEQG 1177
Score = 84.3 bits (207), Expect = 2e-16
Identities = 89/293 (30%), Positives = 112/293 (38%), Gaps = 45/293 (15%)
Query: 72 GSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPW 131
G P P+ R GE+G S AAG G G P +G P V PG+ G G P
Sbjct: 1299 GGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSP----GPVGFPGDPGPPGEPG 1354
Query: 132 REGRVWRPLDR--------RGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKG 181
G+ P D+ GS GE G G P + G G P R+ + G+ G
Sbjct: 1355 PAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAG 1414
Query: 182 ECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGV 241
G P + G P+ +G+ PG G G+P G PG G G
Sbjct: 1415 LEGPPGKTG----PIGPQGAPGKPGPDGLRGIPGPVG----------EQGLPGSPGPDGP 1460
Query: 242 PWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTE 301
P GP P G G KGE G P G + P E+ GEKG+ G+P +
Sbjct: 1461 PGPMGPPGLP----GLKGDSGPKGEKGHPGLIGLIGPPGEQ-------GEKGDRGLPGPQ 1509
Query: 302 GGVWRPLERRASVASPGEKGECGVPWREG--GVWRPLDRRGSVASPGEKGECG 352
G E+ + G G G P G G P +GS G KGE G
Sbjct: 1510 GSSGPKGEQGIT----GPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAG 1558
Score = 81.6 bits (200), Expect = 1e-15
Identities = 88/298 (29%), Positives = 111/298 (37%), Gaps = 28/298 (9%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
P P L+ + G G G+ G+ G P G R +PG G G P G
Sbjct: 1224 PGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGP-------RGPSGAPGADGPQGPP---G 1273
Query: 135 RVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG--GV 192
+ P G PGE GE G+P EGG P R G G G P +G G
Sbjct: 1274 GIGNP-GAVGEKGEPGEAGEPGLP-GEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGD 1331
Query: 193 WRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPL 252
P G V PG+ G G P G+ P + + PGQ G G GP P
Sbjct: 1332 DGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGD-KGDDGEPGQTGSPGPTGEPGPSGPPG 1390
Query: 253 ER-----RGSVASPGEKGECGVPWTEG--GVWRPLERRASVASPGEKGECGVPWTEGGVW 305
+R G GEKG G EG G P+ + + PG G G+P G
Sbjct: 1391 KRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQG 1450
Query: 306 RPLERRASVASPGEKGECGVPWREGGVWRPLDRR-----GSVASPGEKGECGVRWREG 358
P PG G G+P +G ++ G + PGE+GE G R G
Sbjct: 1451 LP-GSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1507
Score = 69.3 bits (168), Expect = 6e-12
Identities = 90/314 (28%), Positives = 113/314 (35%), Gaps = 52/314 (16%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEK------GECGIPWTEGQVWRPLERRASVASPGEK 124
P P + G G+ A GEK GE G+P EG P R G
Sbjct: 1259 PSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLP-GEGGPPGPKGERGEKGESGPS 1317
Query: 125 GECGVPWREGRVW--RPLDRRGSVASPGEKGECGVPWREGGVWRPLER-----RASVASP 177
G G P +G P G V PG+ G G P G P ++ SP
Sbjct: 1318 GAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSP 1377
Query: 178 GQKGE---CGVPWREG--GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVAS 232
G GE G P + G G P R+G + GE G G P + G P+ + +
Sbjct: 1378 GPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTG----PIGPQGAPGK 1433
Query: 233 PGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEK 292
PG G G+P GPV G PG G G P G P G K
Sbjct: 1434 PGPDGLRGIP---GPV-------GEQGLPGSPGPDGPPGPMGPPGLP----GLKGDSGPK 1479
Query: 293 GECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREG--------GVWRPLDRRGSVAS 344
GE G P G + P E+ GEKG+ G+P +G G+ P G
Sbjct: 1480 GEKGHPGLIGLIGPPGEQ-------GEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGP 1532
Query: 345 PGEKGECGVRWREG 358
PG G G + +G
Sbjct: 1533 PGLPGPPGPKGAKG 1546
Score = 67.0 bits (162), Expect = 3e-11
Identities = 88/331 (26%), Positives = 112/331 (33%), Gaps = 57/331 (17%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRP------------------- 111
P +P P G+ G G G G+P +G P
Sbjct: 476 PAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSK 535
Query: 112 -------------LERRASVASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVP 158
+ ++A +A G G G+ R G V P GS GE G+ G P
Sbjct: 536 GPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPP----GSGGLKGEPGDVG-P 590
Query: 159 WREGGVWRPLERRASVASPGQKGECGVPWREG--GVWRPLERR---GSVASPGEKGECGV 213
GV P PG++G G G G P R G PGEKG G
Sbjct: 591 QGPRGVQGP---PGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGD 647
Query: 214 PWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTE 273
P G P + G+ G G+P GP RG + G G G P
Sbjct: 648 PGPSGPPGPPGD-DGERGDDGEVGPRGLPGEPGP-------RGLLGPKGPPGPPGPPGVT 699
Query: 274 GGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREG--G 331
G +P + +V GE G G G P + ++ PGEKG G P G G
Sbjct: 700 GMDGQP-GPKGNVGPQGEPGPPGQQGNPGAQGLP-GPQGAIGPPGEKGPLGKPGLPGMPG 757
Query: 332 VWRPLDRRGSVASPGEKGECGVRWREGRVWY 362
P G PGEKG G +G + Y
Sbjct: 758 ADGPPGHPGKEGPPGEKGGQGPPGPQGPIGY 788
Score = 49.7 bits (117), Expect = 5e-06
Identities = 54/199 (27%), Positives = 71/199 (35%), Gaps = 26/199 (13%)
Query: 68 SAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGEC 127
S PG P P G G G KGE G+ G+ P+ + + PG G
Sbjct: 1386 SGPPGKRGPPGPA----GPEGRQGEKGAKGEAGLEGPPGKTG-PIGPQGAPGKPGPDGLR 1440
Query: 128 GVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERR--------ASVASPGQ 179
G+P G P G PG G G+P +G E+ G+
Sbjct: 1441 GIPGPVGEQGLP-GSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGE 1499
Query: 180 KGECGVPWREGGVWRPLER-----RGSVASPGEKGECGVPWREGRVWRPLERRASVASPG 234
KG+ G+P +G E+ G + PG G G P +G + S G
Sbjct: 1500 KGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGA-------KGSSGPTG 1552
Query: 235 QKGECGVPWREGPVWRPLE 253
KGE G P GP P E
Sbjct: 1553 PKGEAGHPGPPGPPGPPGE 1571
Score = 44.3 bits (103), Expect = 2e-04
Identities = 49/164 (29%), Positives = 62/164 (37%), Gaps = 38/164 (23%)
Query: 68 SAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGEC 127
S P P P + G G S GEKG G+ G + P E+ GEKG+
Sbjct: 1454 SPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGL---IGLIGPPGEQ-------GEKGDR 1503
Query: 128 GVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPW 187
G+P +G S G KGE G+ G + PG G G P
Sbjct: 1504 GLPGPQG-------------SSGPKGEQGITGPSG----------PIGPPGPPGLPGPPG 1540
Query: 188 REG--GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRAS 229
+G G P +G PG G G P G V +PL +AS
Sbjct: 1541 PKGAKGSSGPTGPKGEAGHPGPPGPPGPP---GEVIQPLPIQAS 1581
>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein
[Homo sapiens]
Length = 1650
Score = 94.7 bits (234), Expect = 1e-19
Identities = 97/316 (30%), Positives = 119/316 (37%), Gaps = 38/316 (12%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
P P PR ++ +DG G GEKGE G P +G + + R V PG +GE G
Sbjct: 627 PLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGD-RGEVGVPGSRGEDGPE 685
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGV--- 185
+GR P G GEKG+ GVP G G P PG GE G
Sbjct: 686 GPKGRT-GPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 744
Query: 186 -----PWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLER-----RASVASPGQ 235
P E G P +RG + G+ G G +G P ER + PG
Sbjct: 745 SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 804
Query: 236 KGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEG-----GVWRPLERRASVASPG 290
KG G P ++G P +RG V G+ G G P G G P+ R PG
Sbjct: 805 KGPPGPPGKDGLPGHP-GQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPG 863
Query: 291 EKGECGVPWTEG--------------GVWRPLERRASVASPGEKGECGVPWREGGVWRPL 336
GE G+P T G G P R G G G P +G P
Sbjct: 864 PPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNE-GPS 922
Query: 337 DRRGSVASPGEKGECG 352
G SPGE+G G
Sbjct: 923 GPPGPAGSPGERGAAG 938
Score = 88.6 bits (218), Expect = 9e-18
Identities = 93/311 (29%), Positives = 117/311 (37%), Gaps = 60/311 (19%)
Query: 67 LSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGE 126
+ +PG V PR R GE+G G G G +G P V PG+ G
Sbjct: 1137 IQGEPG-VKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP----GPVGFPGDPGP 1191
Query: 127 CGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVP 186
G G+ DR G PG+ G G P E G PL +R SPG +G G
Sbjct: 1192 PGEGGPRGQDGAKGDR-GEDGEPGQPGSPG-PTGENGPPGPLGKRGPAGSPGSEGRQGGK 1249
Query: 187 WREG--------GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGE 238
+G G P+ G PG G G+P G+ RP G G+
Sbjct: 1250 GAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRP----------GATGQ 1299
Query: 239 CGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVP 298
G P GP P G G KGE G P G + P E+ GEKG+ G+P
Sbjct: 1300 AGPPGPVGPPGLP----GLRGDAGAKGEKGHPGLIGLIGPPGEQ-------GEKGDRGLP 1348
Query: 299 WTEGGVWRPLERRASVASPGEKGECGVPWREG-----------GVWRPLDRRGSVASPGE 347
+G SPG+KGE G+P G G P +G+ G
Sbjct: 1349 GPQG-------------SPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGP 1395
Query: 348 KGECGVRWREG 358
KGE GV+ G
Sbjct: 1396 KGEKGVQGPPG 1406
Score = 88.2 bits (217), Expect = 1e-17
Identities = 91/290 (31%), Positives = 111/290 (38%), Gaps = 37/290 (12%)
Query: 77 PRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRV 136
PR R G G S A G G G G+ P + + PG KG G P ++G
Sbjct: 759 PRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPN-GFPGPKGPPGPPGKDGLP 817
Query: 137 WRPLDRRGSVASPGEKGECGVPWREG-----GVWRPLERRASVASPGQKGECGVPWREGG 191
P +RG V G+ G G P G G P+ R PG GE G+P G
Sbjct: 818 GHP-GQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG- 875
Query: 192 VWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRP 251
+ G+ PG G G G P ER PG G G+ EGP P
Sbjct: 876 ------KEGTKGDPGPPGAPGKDGPAGLRGFPGER----GLPGTAGGPGLKGNEGPSGPP 925
Query: 252 LERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLER- 310
G SPGE+G G GG P R PG GE GVP +G + P R
Sbjct: 926 ----GPAGSPGERGAAG----SGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIG-PTGRD 976
Query: 311 --RASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
+ V PG G GV +G +G V PG+KG G + G
Sbjct: 977 GVQGPVGLPGPAGPPGVAGEDGD-------KGEVGDPGQKGTKGNKGEHG 1019
Score = 84.7 bits (208), Expect = 1e-16
Identities = 92/313 (29%), Positives = 122/313 (38%), Gaps = 35/313 (11%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLER-----RASVASPGEKG 125
P +P P +R +DG G + G +GE G P GQ P + + ++ GEKG
Sbjct: 531 PPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP---GQQGTPGTQGLPGPQGAIGPHGEKG 587
Query: 126 ECGVPWREGRVWR--PLDRRGSVASPGEKGECGVPWREGGVWRPLER--------RASVA 175
G P G P G PG KG G +G + P R R
Sbjct: 588 PQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKG 647
Query: 176 SPGQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQ 235
G+KGE G P +G + + RG V PG +GE G +GR P G+
Sbjct: 648 HKGEKGEDGFPGFKGDIGVKGD-RGEVGVPGSRGEDGPEGPKGRT-GPTGDPGPPGLMGE 705
Query: 236 KGECGVPWREGPVWR--PLERRGSVASPGEKGECGV--------PWTEGGVWRPLERRAS 285
KG+ GVP G R P G PG GE G P E G P +R
Sbjct: 706 KGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGP 765
Query: 286 VASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASP 345
+ G+ G G +G P ER PG +G G P +G P + G P
Sbjct: 766 RGATGKSGAKGTSGGDGPHGPPGER----GLPGPQGPNGFPGPKGPPGPP-GKDGLPGHP 820
Query: 346 GEKGECGVRWREG 358
G++GE G + + G
Sbjct: 821 GQRGEVGFQGKTG 833
Score = 82.0 bits (201), Expect = 8e-16
Identities = 87/303 (28%), Positives = 110/303 (36%), Gaps = 46/303 (15%)
Query: 69 AKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQ--VWRPLERRASVASPGEKGE 126
A P P+ G G GE GE G P +G+ V P R G+ GE
Sbjct: 1102 AGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGE 1161
Query: 127 CGVPWREGRVWR--PLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECG 184
G P +G P G V PG+ G G EGG R + G +GE G
Sbjct: 1162 PGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG----EGGP------RGQDGAKGDRGEDG 1211
Query: 185 VPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWR 244
P + G P G G++G G P EGR + + G G G P +
Sbjct: 1212 EPGQPGSPG-PTGENGPPGPLGKRGPAGSPGSEGR-------QGGKGAKGDPGAIGAPGK 1263
Query: 245 EGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGV 304
GPV G PG G G+P + G RP PG G G+P G
Sbjct: 1264 TGPVGPA----GPAGKPGPDGLRGLPGSVGQQGRP-GATGQAGPPGPVGPPGLPGLRGDA 1318
Query: 305 WRPLERR-----ASVASPGEKGECGVPWREGGVWRPLDRR--GSVASPGEKGECGVRWRE 357
E+ + PGE+GE G DR G SPG+KGE G+
Sbjct: 1319 GAKGEKGHPGLIGLIGPPGEQGEKG------------DRGLPGPQGSPGQKGEMGIPGAS 1366
Query: 358 GRV 360
G +
Sbjct: 1367 GPI 1369
Score = 78.2 bits (191), Expect = 1e-14
Identities = 80/279 (28%), Positives = 104/279 (37%), Gaps = 58/279 (20%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
GE GH G GE G+P T G+ + G+ G G P ++G P RG
Sbjct: 854 GERGHPGPPGPPGEQGLPGTAGKE----------GTKGDPGPPGAPGKDG----PAGLRG 899
Query: 145 SVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVAS 204
G G G P +G P SPG++G G GG P R G
Sbjct: 900 FPGERGLPGTAGGPGLKGNEG-PSGPPGPAGSPGERGAAG----SGGPIGPPGRPGPQGP 954
Query: 205 PGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEK 264
PG GE GVP +G + G +G G+P GP G G+K
Sbjct: 955 PGAAGEKGVPGEKGPI-------GPTGRDGVQGPVGLPGPAGP-------PGVAGEDGDK 1000
Query: 265 GECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASVASPGE----- 319
GE G P +G + G KGE G P G + P+ + + + GE
Sbjct: 1001 GEVGDPGQKG-------------TKGNKGEHGPPGPPGPI-GPVGQPGAAGADGEPGARG 1046
Query: 320 -KGECGVPWREG-----GVWRPLDRRGSVASPGEKGECG 352
+G G EG G P+ +G GEKGE G
Sbjct: 1047 PQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1085
Score = 78.2 bits (191), Expect = 1e-14
Identities = 87/291 (29%), Positives = 105/291 (36%), Gaps = 58/291 (19%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
G+ G G KGE G P G + V PG G G P G P G
Sbjct: 1004 GDPGQKGTKGNKGEHGPPGPPGPI-------GPVGQPGAAGADGEPGARG----PQGHFG 1052
Query: 145 SVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGVPWREG--------GVWR 194
+ G +G G P G G+ P + G G G P G G
Sbjct: 1053 AKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQG 1112
Query: 195 PLERRGSVASPGEKGE---CGVPWREGR--VWRPLERRASVASPGQKGECGVPWREGPVW 249
P G++ PGEKGE G P +G V P R GQ GE G P +GP
Sbjct: 1113 PPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTG 1172
Query: 250 R--PLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRP 307
P G V PG+ G G EGG R + G++GE G P G
Sbjct: 1173 DDGPKGNPGPVGFPGDPGPPG----EGGP------RGQDGAKGDRGEDGEPGQPG----- 1217
Query: 308 LERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
SPG GE G P PL +RG SPG +G G + +G
Sbjct: 1218 --------SPGPTGENGPPG-------PLGKRGPAGSPGSEGRQGGKGAKG 1253
Score = 77.4 bits (189), Expect = 2e-14
Identities = 97/323 (30%), Positives = 119/323 (36%), Gaps = 53/323 (16%)
Query: 81 RSIDGEAGHSEAAGEKGECGIPWTEG--QVWRPLERRASVASPGEKGECGVPWREGRVWR 138
R + GE+G G KG GIP G + P + S+ GE G G G
Sbjct: 514 RGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGL 573
Query: 139 PLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGVPWREGGVWRPL 196
P +G++ GEKG G P G G P PG KG G +G + P
Sbjct: 574 P-GPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPG 632
Query: 197 ER--------RGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPV 248
R RG GEKGE G P +G + + R V PG +GE G EGP
Sbjct: 633 PRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGD-RGEVGVPGSRGEDG---PEGPK 688
Query: 249 WR--PLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWR 306
R P G GEKG+ GVP G R G KG G P G
Sbjct: 689 GRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR----------QGPKGSLGFPGFPG---- 734
Query: 307 PLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREGRVWYSLDK 366
+ GEKG G+ + G P RG G++G G + G S
Sbjct: 735 ---------ASGEKGARGLSGKSG----PRGERGPTGPRGQRGPRGATGKSGAKGTS--- 778
Query: 367 RGSVPAALASQRHALLALPQPQG 389
G P +R LP PQG
Sbjct: 779 GGDGPHGPPGER----GLPGPQG 797
Score = 75.5 bits (184), Expect = 8e-14
Identities = 95/328 (28%), Positives = 117/328 (35%), Gaps = 51/328 (15%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
P P+ L G+AG AG G G+P G V PGEKG G
Sbjct: 432 PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG-VKGDRGFDGLPGLPGEKGHRGDT 490
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREG-----------------GVWRPLERRAS 173
+G + P G GE G G+P G GV +
Sbjct: 491 GAQG-LPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGP 549
Query: 174 VASPGQKGECGVPWREG--GVWRPLERRGSVASPGEKGECGVPWREGRVWR--PLERRAS 229
S G +GE G P ++G G +G++ GEKG G P G P
Sbjct: 550 KGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGK 609
Query: 230 VASPGQKGECGVPWREGPVWRPLER--------RGSVASPGEKGECGVPWTEGGVWRPLE 281
PG KG G +GP+ P R RG GEKGE G P +G
Sbjct: 610 EGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKG------- 662
Query: 282 RRASVASPGEKGECGVPWTEG--GVWRPLERRASVASP------GEKGECGVPWREG--G 331
+ G++GE GVP + G G P R P GEKG+ GVP G G
Sbjct: 663 ---DIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPG 719
Query: 332 VWRPLDRRGSVASPGEKGECGVRWREGR 359
P G PG GE G R G+
Sbjct: 720 RQGPKGSLGFPGFPGASGEKGARGLSGK 747
Score = 72.8 bits (177), Expect = 5e-13
Identities = 72/253 (28%), Positives = 93/253 (36%), Gaps = 60/253 (23%)
Query: 70 KPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGV 129
+PG +P P GE G G++G G P +EG R+ + G+ G G
Sbjct: 1212 EPGQPGSPGPT----GENGPPGPLGKRGPAGSPGSEG-------RQGGKGAKGDPGAIGA 1260
Query: 130 PWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWRE 189
P + G P+ G PG G G+P G RP PG G G+P
Sbjct: 1261 PGKTG----PVGPAGPAGKPGPDGLRGLPGSVGQQGRP-GATGQAGPPGPVGPPGLPGLR 1315
Query: 190 GGVWRPLERR--------GSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGV 241
G E+ G GEKG+ G+P +G SPGQKGE G+
Sbjct: 1316 GDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQG-------------SPGQKGEMGI 1362
Query: 242 PWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGV---- 297
P GP+ G PG G G P + + G KGE GV
Sbjct: 1363 PGASGPI-------GPGGPPGLPGPAG----------PKGAKGATGPGGPKGEKGVQGPP 1405
Query: 298 --PWTEGGVWRPL 308
P G V +PL
Sbjct: 1406 GHPGPPGEVIQPL 1418
>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein
[Homo sapiens]
Length = 1629
Score = 94.7 bits (234), Expect = 1e-19
Identities = 97/316 (30%), Positives = 119/316 (37%), Gaps = 38/316 (12%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
P P PR ++ +DG G GEKGE G P +G + + R V PG +GE G
Sbjct: 606 PLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGD-RGEVGVPGSRGEDGPE 664
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGV--- 185
+GR P G GEKG+ GVP G G P PG GE G
Sbjct: 665 GPKGRT-GPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 723
Query: 186 -----PWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLER-----RASVASPGQ 235
P E G P +RG + G+ G G +G P ER + PG
Sbjct: 724 SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 783
Query: 236 KGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEG-----GVWRPLERRASVASPG 290
KG G P ++G P +RG V G+ G G P G G P+ R PG
Sbjct: 784 KGPPGPPGKDGLPGHP-GQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPG 842
Query: 291 EKGECGVPWTEG--------------GVWRPLERRASVASPGEKGECGVPWREGGVWRPL 336
GE G+P T G G P R G G G P +G P
Sbjct: 843 PPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNE-GPS 901
Query: 337 DRRGSVASPGEKGECG 352
G SPGE+G G
Sbjct: 902 GPPGPAGSPGERGAAG 917
Score = 88.6 bits (218), Expect = 9e-18
Identities = 93/311 (29%), Positives = 117/311 (37%), Gaps = 60/311 (19%)
Query: 67 LSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGE 126
+ +PG V PR R GE+G G G G +G P V PG+ G
Sbjct: 1116 IQGEPG-VKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP----GPVGFPGDPGP 1170
Query: 127 CGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVP 186
G G+ DR G PG+ G G P E G PL +R SPG +G G
Sbjct: 1171 PGEGGPRGQDGAKGDR-GEDGEPGQPGSPG-PTGENGPPGPLGKRGPAGSPGSEGRQGGK 1228
Query: 187 WREG--------GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGE 238
+G G P+ G PG G G+P G+ RP G G+
Sbjct: 1229 GAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRP----------GATGQ 1278
Query: 239 CGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVP 298
G P GP P G G KGE G P G + P E+ GEKG+ G+P
Sbjct: 1279 AGPPGPVGPPGLP----GLRGDAGAKGEKGHPGLIGLIGPPGEQ-------GEKGDRGLP 1327
Query: 299 WTEGGVWRPLERRASVASPGEKGECGVPWREG-----------GVWRPLDRRGSVASPGE 347
+G SPG+KGE G+P G G P +G+ G
Sbjct: 1328 GPQG-------------SPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGP 1374
Query: 348 KGECGVRWREG 358
KGE GV+ G
Sbjct: 1375 KGEKGVQGPPG 1385
Score = 88.2 bits (217), Expect = 1e-17
Identities = 91/290 (31%), Positives = 111/290 (38%), Gaps = 37/290 (12%)
Query: 77 PRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRV 136
PR R G G S A G G G G+ P + + PG KG G P ++G
Sbjct: 738 PRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPN-GFPGPKGPPGPPGKDGLP 796
Query: 137 WRPLDRRGSVASPGEKGECGVPWREG-----GVWRPLERRASVASPGQKGECGVPWREGG 191
P +RG V G+ G G P G G P+ R PG GE G+P G
Sbjct: 797 GHP-GQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG- 854
Query: 192 VWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRP 251
+ G+ PG G G G P ER PG G G+ EGP P
Sbjct: 855 ------KEGTKGDPGPPGAPGKDGPAGLRGFPGER----GLPGTAGGPGLKGNEGPSGPP 904
Query: 252 LERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLER- 310
G SPGE+G G GG P R PG GE GVP +G + P R
Sbjct: 905 ----GPAGSPGERGAAG----SGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIG-PTGRD 955
Query: 311 --RASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
+ V PG G GV +G +G V PG+KG G + G
Sbjct: 956 GVQGPVGLPGPAGPPGVAGEDGD-------KGEVGDPGQKGTKGNKGEHG 998
Score = 84.7 bits (208), Expect = 1e-16
Identities = 92/313 (29%), Positives = 122/313 (38%), Gaps = 35/313 (11%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLER-----RASVASPGEKG 125
P +P P +R +DG G + G +GE G P GQ P + + ++ GEKG
Sbjct: 510 PPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP---GQQGTPGTQGLPGPQGAIGPHGEKG 566
Query: 126 ECGVPWREGRVWR--PLDRRGSVASPGEKGECGVPWREGGVWRPLER--------RASVA 175
G P G P G PG KG G +G + P R R
Sbjct: 567 PQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKG 626
Query: 176 SPGQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQ 235
G+KGE G P +G + + RG V PG +GE G +GR P G+
Sbjct: 627 HKGEKGEDGFPGFKGDIGVKGD-RGEVGVPGSRGEDGPEGPKGRT-GPTGDPGPPGLMGE 684
Query: 236 KGECGVPWREGPVWR--PLERRGSVASPGEKGECGV--------PWTEGGVWRPLERRAS 285
KG+ GVP G R P G PG GE G P E G P +R
Sbjct: 685 KGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGP 744
Query: 286 VASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASP 345
+ G+ G G +G P ER PG +G G P +G P + G P
Sbjct: 745 RGATGKSGAKGTSGGDGPHGPPGER----GLPGPQGPNGFPGPKGPPGPP-GKDGLPGHP 799
Query: 346 GEKGECGVRWREG 358
G++GE G + + G
Sbjct: 800 GQRGEVGFQGKTG 812
Score = 82.0 bits (201), Expect = 8e-16
Identities = 87/303 (28%), Positives = 110/303 (36%), Gaps = 46/303 (15%)
Query: 69 AKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQ--VWRPLERRASVASPGEKGE 126
A P P+ G G GE GE G P +G+ V P R G+ GE
Sbjct: 1081 AGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGE 1140
Query: 127 CGVPWREGRVWR--PLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECG 184
G P +G P G V PG+ G G EGG R + G +GE G
Sbjct: 1141 PGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG----EGGP------RGQDGAKGDRGEDG 1190
Query: 185 VPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWR 244
P + G P G G++G G P EGR + + G G G P +
Sbjct: 1191 EPGQPGSPG-PTGENGPPGPLGKRGPAGSPGSEGR-------QGGKGAKGDPGAIGAPGK 1242
Query: 245 EGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGV 304
GPV G PG G G+P + G RP PG G G+P G
Sbjct: 1243 TGPVGPA----GPAGKPGPDGLRGLPGSVGQQGRP-GATGQAGPPGPVGPPGLPGLRGDA 1297
Query: 305 WRPLERR-----ASVASPGEKGECGVPWREGGVWRPLDRR--GSVASPGEKGECGVRWRE 357
E+ + PGE+GE G DR G SPG+KGE G+
Sbjct: 1298 GAKGEKGHPGLIGLIGPPGEQGEKG------------DRGLPGPQGSPGQKGEMGIPGAS 1345
Query: 358 GRV 360
G +
Sbjct: 1346 GPI 1348
Score = 78.2 bits (191), Expect = 1e-14
Identities = 80/279 (28%), Positives = 104/279 (37%), Gaps = 58/279 (20%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
GE GH G GE G+P T G+ + G+ G G P ++G P RG
Sbjct: 833 GERGHPGPPGPPGEQGLPGTAGKE----------GTKGDPGPPGAPGKDG----PAGLRG 878
Query: 145 SVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVAS 204
G G G P +G P SPG++G G GG P R G
Sbjct: 879 FPGERGLPGTAGGPGLKGNEG-PSGPPGPAGSPGERGAAG----SGGPIGPPGRPGPQGP 933
Query: 205 PGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEK 264
PG GE GVP +G + G +G G+P GP G G+K
Sbjct: 934 PGAAGEKGVPGEKGPI-------GPTGRDGVQGPVGLPGPAGP-------PGVAGEDGDK 979
Query: 265 GECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASVASPGE----- 319
GE G P +G + G KGE G P G + P+ + + + GE
Sbjct: 980 GEVGDPGQKG-------------TKGNKGEHGPPGPPGPI-GPVGQPGAAGADGEPGARG 1025
Query: 320 -KGECGVPWREG-----GVWRPLDRRGSVASPGEKGECG 352
+G G EG G P+ +G GEKGE G
Sbjct: 1026 PQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1064
Score = 78.2 bits (191), Expect = 1e-14
Identities = 87/291 (29%), Positives = 105/291 (36%), Gaps = 58/291 (19%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
G+ G G KGE G P G + V PG G G P G P G
Sbjct: 983 GDPGQKGTKGNKGEHGPPGPPGPI-------GPVGQPGAAGADGEPGARG----PQGHFG 1031
Query: 145 SVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGVPWREG--------GVWR 194
+ G +G G P G G+ P + G G G P G G
Sbjct: 1032 AKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQG 1091
Query: 195 PLERRGSVASPGEKGE---CGVPWREGR--VWRPLERRASVASPGQKGECGVPWREGPVW 249
P G++ PGEKGE G P +G V P R GQ GE G P +GP
Sbjct: 1092 PPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTG 1151
Query: 250 R--PLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRP 307
P G V PG+ G G EGG R + G++GE G P G
Sbjct: 1152 DDGPKGNPGPVGFPGDPGPPG----EGGP------RGQDGAKGDRGEDGEPGQPG----- 1196
Query: 308 LERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
SPG GE G P PL +RG SPG +G G + +G
Sbjct: 1197 --------SPGPTGENGPPG-------PLGKRGPAGSPGSEGRQGGKGAKG 1232
Score = 77.4 bits (189), Expect = 2e-14
Identities = 97/323 (30%), Positives = 119/323 (36%), Gaps = 53/323 (16%)
Query: 81 RSIDGEAGHSEAAGEKGECGIPWTEG--QVWRPLERRASVASPGEKGECGVPWREGRVWR 138
R + GE+G G KG GIP G + P + S+ GE G G G
Sbjct: 493 RGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGL 552
Query: 139 PLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGVPWREGGVWRPL 196
P +G++ GEKG G P G G P PG KG G +G + P
Sbjct: 553 P-GPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPG 611
Query: 197 ER--------RGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPV 248
R RG GEKGE G P +G + + R V PG +GE G EGP
Sbjct: 612 PRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGD-RGEVGVPGSRGEDG---PEGPK 667
Query: 249 WR--PLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWR 306
R P G GEKG+ GVP G R G KG G P G
Sbjct: 668 GRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR----------QGPKGSLGFPGFPG---- 713
Query: 307 PLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREGRVWYSLDK 366
+ GEKG G+ + G P RG G++G G + G S
Sbjct: 714 ---------ASGEKGARGLSGKSG----PRGERGPTGPRGQRGPRGATGKSGAKGTS--- 757
Query: 367 RGSVPAALASQRHALLALPQPQG 389
G P +R LP PQG
Sbjct: 758 GGDGPHGPPGER----GLPGPQG 776
Score = 75.5 bits (184), Expect = 8e-14
Identities = 95/328 (28%), Positives = 117/328 (35%), Gaps = 51/328 (15%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
P P+ L G+AG AG G G+P G V PGEKG G
Sbjct: 411 PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG-VKGDRGFDGLPGLPGEKGHRGDT 469
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREG-----------------GVWRPLERRAS 173
+G + P G GE G G+P G GV +
Sbjct: 470 GAQG-LPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGP 528
Query: 174 VASPGQKGECGVPWREG--GVWRPLERRGSVASPGEKGECGVPWREGRVWR--PLERRAS 229
S G +GE G P ++G G +G++ GEKG G P G P
Sbjct: 529 KGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGK 588
Query: 230 VASPGQKGECGVPWREGPVWRPLER--------RGSVASPGEKGECGVPWTEGGVWRPLE 281
PG KG G +GP+ P R RG GEKGE G P +G
Sbjct: 589 EGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKG------- 641
Query: 282 RRASVASPGEKGECGVPWTEG--GVWRPLERRASVASP------GEKGECGVPWREG--G 331
+ G++GE GVP + G G P R P GEKG+ GVP G G
Sbjct: 642 ---DIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPG 698
Query: 332 VWRPLDRRGSVASPGEKGECGVRWREGR 359
P G PG GE G R G+
Sbjct: 699 RQGPKGSLGFPGFPGASGEKGARGLSGK 726
Score = 72.8 bits (177), Expect = 5e-13
Identities = 72/253 (28%), Positives = 93/253 (36%), Gaps = 60/253 (23%)
Query: 70 KPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGV 129
+PG +P P GE G G++G G P +EG R+ + G+ G G
Sbjct: 1191 EPGQPGSPGPT----GENGPPGPLGKRGPAGSPGSEG-------RQGGKGAKGDPGAIGA 1239
Query: 130 PWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWRE 189
P + G P+ G PG G G+P G RP PG G G+P
Sbjct: 1240 PGKTG----PVGPAGPAGKPGPDGLRGLPGSVGQQGRP-GATGQAGPPGPVGPPGLPGLR 1294
Query: 190 GGVWRPLERR--------GSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGV 241
G E+ G GEKG+ G+P +G SPGQKGE G+
Sbjct: 1295 GDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQG-------------SPGQKGEMGI 1341
Query: 242 PWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGV---- 297
P GP+ G PG G G P + + G KGE GV
Sbjct: 1342 PGASGPI-------GPGGPPGLPGPAG----------PKGAKGATGPGGPKGEKGVQGPP 1384
Query: 298 --PWTEGGVWRPL 308
P G V +PL
Sbjct: 1385 GHPGPPGEVIQPL 1397
>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
sapiens]
Length = 1736
Score = 94.7 bits (234), Expect = 1e-19
Identities = 97/316 (30%), Positives = 119/316 (37%), Gaps = 38/316 (12%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
P P PR ++ +DG G GEKGE G P +G + + R V PG +GE G
Sbjct: 713 PLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGD-RGEVGVPGSRGEDGPE 771
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGV--- 185
+GR P G GEKG+ GVP G G P PG GE G
Sbjct: 772 GPKGRT-GPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 830
Query: 186 -----PWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLER-----RASVASPGQ 235
P E G P +RG + G+ G G +G P ER + PG
Sbjct: 831 SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 890
Query: 236 KGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEG-----GVWRPLERRASVASPG 290
KG G P ++G P +RG V G+ G G P G G P+ R PG
Sbjct: 891 KGPPGPPGKDGLPGHP-GQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPG 949
Query: 291 EKGECGVPWTEG--------------GVWRPLERRASVASPGEKGECGVPWREGGVWRPL 336
GE G+P T G G P R G G G P +G P
Sbjct: 950 PPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNE-GPS 1008
Query: 337 DRRGSVASPGEKGECG 352
G SPGE+G G
Sbjct: 1009 GPPGPAGSPGERGAAG 1024
Score = 88.6 bits (218), Expect = 9e-18
Identities = 93/311 (29%), Positives = 117/311 (37%), Gaps = 60/311 (19%)
Query: 67 LSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGE 126
+ +PG V PR R GE+G G G G +G P V PG+ G
Sbjct: 1223 IQGEPG-VKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP----GPVGFPGDPGP 1277
Query: 127 CGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVP 186
G G+ DR G PG+ G G P E G PL +R SPG +G G
Sbjct: 1278 PGEGGPRGQDGAKGDR-GEDGEPGQPGSPG-PTGENGPPGPLGKRGPAGSPGSEGRQGGK 1335
Query: 187 WREG--------GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGE 238
+G G P+ G PG G G+P G+ RP G G+
Sbjct: 1336 GAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRP----------GATGQ 1385
Query: 239 CGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVP 298
G P GP P G G KGE G P G + P E+ GEKG+ G+P
Sbjct: 1386 AGPPGPVGPPGLP----GLRGDAGAKGEKGHPGLIGLIGPPGEQ-------GEKGDRGLP 1434
Query: 299 WTEGGVWRPLERRASVASPGEKGECGVPWREG-----------GVWRPLDRRGSVASPGE 347
+G SPG+KGE G+P G G P +G+ G
Sbjct: 1435 GPQG-------------SPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGP 1481
Query: 348 KGECGVRWREG 358
KGE GV+ G
Sbjct: 1482 KGEKGVQGPPG 1492
Score = 88.2 bits (217), Expect = 1e-17
Identities = 91/290 (31%), Positives = 111/290 (38%), Gaps = 37/290 (12%)
Query: 77 PRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRV 136
PR R G G S A G G G G+ P + + PG KG G P ++G
Sbjct: 845 PRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPN-GFPGPKGPPGPPGKDGLP 903
Query: 137 WRPLDRRGSVASPGEKGECGVPWREG-----GVWRPLERRASVASPGQKGECGVPWREGG 191
P +RG V G+ G G P G G P+ R PG GE G+P G
Sbjct: 904 GHP-GQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG- 961
Query: 192 VWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRP 251
+ G+ PG G G G P ER PG G G+ EGP P
Sbjct: 962 ------KEGTKGDPGPPGAPGKDGPAGLRGFPGER----GLPGTAGGPGLKGNEGPSGPP 1011
Query: 252 LERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLER- 310
G SPGE+G G GG P R PG GE GVP +G + P R
Sbjct: 1012 ----GPAGSPGERGAAG----SGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIG-PTGRD 1062
Query: 311 --RASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
+ V PG G GV +G +G V PG+KG G + G
Sbjct: 1063 GVQGPVGLPGPAGPPGVAGEDGD-------KGEVGDPGQKGTKGNKGEHG 1105
Score = 84.7 bits (208), Expect = 1e-16
Identities = 92/313 (29%), Positives = 122/313 (38%), Gaps = 35/313 (11%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLER-----RASVASPGEKG 125
P +P P +R +DG G + G +GE G P GQ P + + ++ GEKG
Sbjct: 617 PPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP---GQQGTPGTQGLPGPQGAIGPHGEKG 673
Query: 126 ECGVPWREGRVWR--PLDRRGSVASPGEKGECGVPWREGGVWRPLER--------RASVA 175
G P G P G PG KG G +G + P R R
Sbjct: 674 PQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKG 733
Query: 176 SPGQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQ 235
G+KGE G P +G + + RG V PG +GE G +GR P G+
Sbjct: 734 HKGEKGEDGFPGFKGDIGVKGD-RGEVGVPGSRGEDGPEGPKGRT-GPTGDPGPPGLMGE 791
Query: 236 KGECGVPWREGPVWR--PLERRGSVASPGEKGECGV--------PWTEGGVWRPLERRAS 285
KG+ GVP G R P G PG GE G P E G P +R
Sbjct: 792 KGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGP 851
Query: 286 VASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASP 345
+ G+ G G +G P ER PG +G G P +G P + G P
Sbjct: 852 RGATGKSGAKGTSGGDGPHGPPGER----GLPGPQGPNGFPGPKGPPGPP-GKDGLPGHP 906
Query: 346 GEKGECGVRWREG 358
G++GE G + + G
Sbjct: 907 GQRGEVGFQGKTG 919
Score = 82.0 bits (201), Expect = 8e-16
Identities = 87/303 (28%), Positives = 110/303 (36%), Gaps = 46/303 (15%)
Query: 69 AKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQ--VWRPLERRASVASPGEKGE 126
A P P+ G G GE GE G P +G+ V P R G+ GE
Sbjct: 1188 AGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGE 1247
Query: 127 CGVPWREGRVWR--PLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECG 184
G P +G P G V PG+ G G EGG R + G +GE G
Sbjct: 1248 PGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG----EGGP------RGQDGAKGDRGEDG 1297
Query: 185 VPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWR 244
P + G P G G++G G P EGR + + G G G P +
Sbjct: 1298 EPGQPGSPG-PTGENGPPGPLGKRGPAGSPGSEGR-------QGGKGAKGDPGAIGAPGK 1349
Query: 245 EGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGV 304
GPV G PG G G+P + G RP PG G G+P G
Sbjct: 1350 TGPVGPA----GPAGKPGPDGLRGLPGSVGQQGRP-GATGQAGPPGPVGPPGLPGLRGDA 1404
Query: 305 WRPLERR-----ASVASPGEKGECGVPWREGGVWRPLDRR--GSVASPGEKGECGVRWRE 357
E+ + PGE+GE G DR G SPG+KGE G+
Sbjct: 1405 GAKGEKGHPGLIGLIGPPGEQGEKG------------DRGLPGPQGSPGQKGEMGIPGAS 1452
Query: 358 GRV 360
G +
Sbjct: 1453 GPI 1455
Score = 78.2 bits (191), Expect = 1e-14
Identities = 80/279 (28%), Positives = 104/279 (37%), Gaps = 58/279 (20%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
GE GH G GE G+P T G+ + G+ G G P ++G P RG
Sbjct: 940 GERGHPGPPGPPGEQGLPGTAGKE----------GTKGDPGPPGAPGKDG----PAGLRG 985
Query: 145 SVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVAS 204
G G G P +G P SPG++G G GG P R G
Sbjct: 986 FPGERGLPGTAGGPGLKGNEG-PSGPPGPAGSPGERGAAG----SGGPIGPPGRPGPQGP 1040
Query: 205 PGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEK 264
PG GE GVP +G + G +G G+P GP G G+K
Sbjct: 1041 PGAAGEKGVPGEKGPI-------GPTGRDGVQGPVGLPGPAGP-------PGVAGEDGDK 1086
Query: 265 GECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASVASPGE----- 319
GE G P +G + G KGE G P G + P+ + + + GE
Sbjct: 1087 GEVGDPGQKG-------------TKGNKGEHGPPGPPGPI-GPVGQPGAAGADGEPGARG 1132
Query: 320 -KGECGVPWREG-----GVWRPLDRRGSVASPGEKGECG 352
+G G EG G P+ +G GEKGE G
Sbjct: 1133 PQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1171
Score = 78.2 bits (191), Expect = 1e-14
Identities = 87/291 (29%), Positives = 105/291 (36%), Gaps = 58/291 (19%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
G+ G G KGE G P G + V PG G G P G P G
Sbjct: 1090 GDPGQKGTKGNKGEHGPPGPPGPI-------GPVGQPGAAGADGEPGARG----PQGHFG 1138
Query: 145 SVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGVPWREG--------GVWR 194
+ G +G G P G G+ P + G G G P G G
Sbjct: 1139 AKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQG 1198
Query: 195 PLERRGSVASPGEKGE---CGVPWREGR--VWRPLERRASVASPGQKGECGVPWREGPVW 249
P G++ PGEKGE G P +G V P R GQ GE G P +GP
Sbjct: 1199 PPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTG 1258
Query: 250 R--PLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRP 307
P G V PG+ G G EGG R + G++GE G P G
Sbjct: 1259 DDGPKGNPGPVGFPGDPGPPG----EGGP------RGQDGAKGDRGEDGEPGQPG----- 1303
Query: 308 LERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
SPG GE G P PL +RG SPG +G G + +G
Sbjct: 1304 --------SPGPTGENGPPG-------PLGKRGPAGSPGSEGRQGGKGAKG 1339
Score = 77.4 bits (189), Expect = 2e-14
Identities = 97/323 (30%), Positives = 119/323 (36%), Gaps = 53/323 (16%)
Query: 81 RSIDGEAGHSEAAGEKGECGIPWTEG--QVWRPLERRASVASPGEKGECGVPWREGRVWR 138
R + GE+G G KG GIP G + P + S+ GE G G G
Sbjct: 600 RGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGL 659
Query: 139 PLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGVPWREGGVWRPL 196
P +G++ GEKG G P G G P PG KG G +G + P
Sbjct: 660 P-GPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPG 718
Query: 197 ER--------RGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPV 248
R RG GEKGE G P +G + + R V PG +GE G EGP
Sbjct: 719 PRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGD-RGEVGVPGSRGEDG---PEGPK 774
Query: 249 WR--PLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWR 306
R P G GEKG+ GVP G R G KG G P G
Sbjct: 775 GRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR----------QGPKGSLGFPGFPG---- 820
Query: 307 PLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREGRVWYSLDK 366
+ GEKG G+ + G P RG G++G G + G S
Sbjct: 821 ---------ASGEKGARGLSGKSG----PRGERGPTGPRGQRGPRGATGKSGAKGTS--- 864
Query: 367 RGSVPAALASQRHALLALPQPQG 389
G P +R LP PQG
Sbjct: 865 GGDGPHGPPGER----GLPGPQG 883
Score = 75.5 bits (184), Expect = 8e-14
Identities = 95/328 (28%), Positives = 117/328 (35%), Gaps = 51/328 (15%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
P P+ L G+AG AG G G+P G V PGEKG G
Sbjct: 518 PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG-VKGDRGFDGLPGLPGEKGHRGDT 576
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREG-----------------GVWRPLERRAS 173
+G + P G GE G G+P G GV +
Sbjct: 577 GAQG-LPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGP 635
Query: 174 VASPGQKGECGVPWREG--GVWRPLERRGSVASPGEKGECGVPWREGRVWR--PLERRAS 229
S G +GE G P ++G G +G++ GEKG G P G P
Sbjct: 636 KGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGK 695
Query: 230 VASPGQKGECGVPWREGPVWRPLER--------RGSVASPGEKGECGVPWTEGGVWRPLE 281
PG KG G +GP+ P R RG GEKGE G P +G
Sbjct: 696 EGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKG------- 748
Query: 282 RRASVASPGEKGECGVPWTEG--GVWRPLERRASVASP------GEKGECGVPWREG--G 331
+ G++GE GVP + G G P R P GEKG+ GVP G G
Sbjct: 749 ---DIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPG 805
Query: 332 VWRPLDRRGSVASPGEKGECGVRWREGR 359
P G PG GE G R G+
Sbjct: 806 RQGPKGSLGFPGFPGASGEKGARGLSGK 833
Score = 72.8 bits (177), Expect = 5e-13
Identities = 72/253 (28%), Positives = 93/253 (36%), Gaps = 60/253 (23%)
Query: 70 KPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGV 129
+PG +P P GE G G++G G P +EG R+ + G+ G G
Sbjct: 1298 EPGQPGSPGPT----GENGPPGPLGKRGPAGSPGSEG-------RQGGKGAKGDPGAIGA 1346
Query: 130 PWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWRE 189
P + G P+ G PG G G+P G RP PG G G+P
Sbjct: 1347 PGKTG----PVGPAGPAGKPGPDGLRGLPGSVGQQGRP-GATGQAGPPGPVGPPGLPGLR 1401
Query: 190 GGVWRPLERR--------GSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGV 241
G E+ G GEKG+ G+P +G SPGQKGE G+
Sbjct: 1402 GDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQG-------------SPGQKGEMGI 1448
Query: 242 PWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGV---- 297
P GP+ G PG G G P + + G KGE GV
Sbjct: 1449 PGASGPI-------GPGGPPGLPGPAG----------PKGAKGATGPGGPKGEKGVQGPP 1491
Query: 298 --PWTEGGVWRPL 308
P G V +PL
Sbjct: 1492 GHPGPPGEVIQPL 1504
>gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]
Length = 1714
Score = 94.7 bits (234), Expect = 1e-19
Identities = 92/310 (29%), Positives = 125/310 (40%), Gaps = 42/310 (13%)
Query: 67 LSAKPGS-----VPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASP 121
L PGS +P LR + G+ G GE G G P TEG+ P
Sbjct: 976 LQGLPGSTGDRGLPGEPGLRGLQGDVG---PPGEMGMEGPPGTEGE-------SGLQGEP 1025
Query: 122 GEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKG 181
G KG+ G G P G PG GE G+ ++G P R G+KG
Sbjct: 1026 GAKGDVGTAGSVGGTGEP----GLRGEPGAPGEEGLQGKDGLKGVP-GGRGLPGEDGEKG 1080
Query: 182 ECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGV 241
E G+P G+ PL R G PG +G G+P + GR + + + + G+ G G
Sbjct: 1081 EMGLP----GIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGD-KGQIGPTGEVGSRGP 1135
Query: 242 PWREGPVWRPLER--RGSVAS---PGEKGECGVPWTEGGVWRPLERRASVASPGEKGECG 296
P + G R RG+V G GE G+P G +P PG KGE G
Sbjct: 1136 PGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQP----GPSGLPGPKGEKG 1191
Query: 297 VPWTEGGVWRPLERRASVASPGEKGECGVPWREG--------GVWRPLDRRGSVASPGEK 348
P + V P R G++GE G P EG G+ ++G PG++
Sbjct: 1192 YPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQ 1251
Query: 349 GECGVRWREG 358
GE G++ G
Sbjct: 1252 GEQGLKGERG 1261
Score = 91.3 bits (225), Expect = 1e-18
Identities = 113/393 (28%), Positives = 149/393 (37%), Gaps = 71/393 (18%)
Query: 9 GPPRVERAECGASAGALTIVSSHGGDSDKDLCARTQ------IYGAQPREDQMGSVEKLT 62
GPP E G + I +G + K L + G Q E +G+ +L
Sbjct: 765 GPPGPE-----GFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELG 819
Query: 63 TSAFLSAKPGSV-----PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLER--R 115
KPG P P L+ G+ G+ GE G G+P G E+ R
Sbjct: 820 PRG----KPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGER 875
Query: 116 AS---VASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRA 172
S + GEKG G P G V P+ G + PG G G P +G P +R
Sbjct: 876 GSPGPLGPQGEKGVMGYPGPPG-VPGPI---GPLGLPGHVGARGPPGSQG----PKGQRG 927
Query: 173 SVASPGQKGECGVPWREG-----GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLER- 226
S G GE G+ +G G P G +PGE+G G P +G +R
Sbjct: 928 SRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRG 987
Query: 227 ----------RASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGV 276
+ V PG+ G G P EG G PG KG+ G + GG
Sbjct: 988 LPGEPGLRGLQGDVGPPGEMGMEGPPGTEG-------ESGLQGEPGAKGDVGTAGSVGGT 1040
Query: 277 WRPLERRASVASPGEKG---ECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVW 333
P R +PGE+G + G+ GG P E GEKGE G+P G+
Sbjct: 1041 GEP-GLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGE-------DGEKGEMGLP----GII 1088
Query: 334 RPLDRRGSVASPGEKGECGVRWREGRVWYSLDK 366
PL R G PG +G G+ + GR DK
Sbjct: 1089 GPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDK 1121
Score = 90.5 bits (223), Expect = 2e-18
Identities = 93/290 (32%), Positives = 115/290 (39%), Gaps = 37/290 (12%)
Query: 81 RSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPL 140
R G+ G G G+ G+P G R L+ V PGE G G P EG
Sbjct: 968 RGFQGKPGLQGLPGSTGDRGLPGEPGL--RGLQ--GDVGPPGEMGMEGPPGTEGE----- 1018
Query: 141 DRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRG 200
G PG KG+ G GG P R PG GE G+ ++G P RG
Sbjct: 1019 --SGLQGEPGAKGDVGTAGSVGGTGEPGLR----GEPGAPGEEGLQGKDGLKGVP-GGRG 1071
Query: 201 SVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLER--RGSV 258
GEKGE G+P G PL R PG +G G+P + G RP ++ +G +
Sbjct: 1072 LPGEDGEKGEMGLPGIIG----PLGRSGQTGLPGPEGIVGIPGQRG---RPGKKGDKGQI 1124
Query: 259 ASPGEKGECGVPWTEG--GVWRPLERRASVAS---PGEKGECGVPWTEGGVWRPLERRAS 313
GE G G P G G R +V G GE G+P G +P
Sbjct: 1125 GPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQP----GP 1180
Query: 314 VASPGEKGECGVPWREGGVWRPLDRRGS---VASPGEKGECGVRWREGRV 360
PG KGE G P + V P RG V GE+GE G +G V
Sbjct: 1181 SGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHV 1230
Score = 89.7 bits (221), Expect = 4e-18
Identities = 85/296 (28%), Positives = 116/296 (39%), Gaps = 49/296 (16%)
Query: 80 LRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRP 139
L+ + G G GEKGE G+P G PL R PG +G G+P + GR +
Sbjct: 1063 LKGVPGGRGLPGEDGEKGEMGLPGIIG----PLGRSGQTGLPGPEGIVGIPGQRGRPGKK 1118
Query: 140 LDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVAS---PGQKGECGVPWREGGVWR 194
D+ G + GE G G P + G G R +V G GE G+P G +
Sbjct: 1119 GDK-GQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQ 1177
Query: 195 PLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLER 254
P G PG KGE G P + V P PG +GE G +G
Sbjct: 1178 P----GPSGLPGPKGEKGYPGEDSTVLGP---------PGPRGEPGPVGDQG-------E 1217
Query: 255 RGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASV 314
RG + G KG GVP G + + PG++GE G+ G +
Sbjct: 1218 RGEPGAEGYKGHVGVPGLRGATGQ----QGPPGEPGDQGEQGLKGERGSEGN----KGKK 1269
Query: 315 ASPGEKGECGVPWREG-----------GVWRPLDRRGSVASPGEKGECGVRWREGR 359
+PG G+ G+P +G G G + PG++G G+R GR
Sbjct: 1270 GAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGR 1325
Score = 79.0 bits (193), Expect = 7e-15
Identities = 95/325 (29%), Positives = 125/325 (38%), Gaps = 52/325 (16%)
Query: 71 PGSVPAP------RPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRP------------- 111
P +P P + L I G+ G AGE GE G P +G V P
Sbjct: 694 PAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSG 753
Query: 112 ------LERRASVASP-GEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREG-- 162
L+ + P G G+ G+P + G P G+ PG G G EG
Sbjct: 754 QTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPE-GPKGLLGNRGPPGPPGLKGTQGEEGPI 812
Query: 163 GVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWR 222
G + L R PGQKG G P E G+ + +G++ GE G G+P G
Sbjct: 813 GAFGELGPR---GKPGQKGYAGEPGPE-GLKGEVGDQGNIGKIGETGPVGLPGEVGMTGS 868
Query: 223 PLER--RASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPL 280
E+ R S G +GE GV GP P G + PG G G P ++G P
Sbjct: 869 IGEKGERGSPGPLGPQGEKGVMGYPGPPGVP-GPIGPLGLPGHVGARGPPGSQG----PK 923
Query: 281 ERRASVASPGEKGECGVPWTEG-----GVWRPLERRASVASPGEKGECGVPWREGGVWRP 335
+R S G GE G+ +G G P +PGE+G G P +G
Sbjct: 924 GQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQG----- 978
Query: 336 LDRRGSVASPGEKGECGVRWREGRV 360
GS G GE G+R +G V
Sbjct: 979 --LPGSTGDRGLPGEPGLRGLQGDV 1001
Score = 75.1 bits (183), Expect = 1e-13
Identities = 85/312 (27%), Positives = 112/312 (35%), Gaps = 65/312 (20%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRAS---VASPGEKGEC 127
P P R G+ G S G KGE G P + V P R V GE+GE
Sbjct: 1162 PDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEP 1221
Query: 128 GVPWREGRVWRP-----LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGE 182
G +G V P ++G PG++GE G+ G + +PG G+
Sbjct: 1222 GAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSE----GNKGKKGAPGPSGK 1277
Query: 183 CGVPWREG-----------GVWRPLERRGSVASPGEKGECGV---PWREGRVWRPLERRA 228
G+P +G G G + PG++G G+ P R G P
Sbjct: 1278 PGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAP----- 1332
Query: 229 SVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVAS 288
PG KG G+P GS G KGE G+P G +R +
Sbjct: 1333 --GPPGVKGSSGLP-------------GSPGIQGPKGEQGLPGQPG----IQGKRGHRGA 1373
Query: 289 PGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREG--GVWRPLDRRGSVASPG 346
G++G CG P +G PGE G G+ +G G P G V G
Sbjct: 1374 QGDQGPCGDPGLKG-------------QPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISG 1420
Query: 347 EKGECGVRWREG 358
KG G R G
Sbjct: 1421 PKGPIGHRGNTG 1432
Score = 73.2 bits (178), Expect = 4e-13
Identities = 82/292 (28%), Positives = 117/292 (40%), Gaps = 19/292 (6%)
Query: 69 AKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECG 128
A P P P+ + G G + G +GE GIP G+ R+ G++G G
Sbjct: 605 AGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFK-GRQGFPGDFGDRGPAG 663
Query: 129 VPWREGRVWRPLDRRGSVASPGEKGECGV--PWREGGVWRPLERRASVASPGQKGECGVP 186
+ G V G PG +G G P G+ P+ + PG KG+ G
Sbjct: 664 LDGSPGLV----GGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQ 719
Query: 187 WREGGVWRP--LERRGSVASPGEKGECGVPWREGRVWRP-LERRASVASP-GQKGECGVP 242
G + P +G+V PG G G G+ P L+ + P G G+ G+P
Sbjct: 720 GTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIP 779
Query: 243 WREGPVWRPLERRGSVASPGEKGECGVPWTEG--GVWRPLERRASVASPGEKGECGVPWT 300
+ GP P G+ PG G G EG G + L R PG+KG G P
Sbjct: 780 GQNGPE-GPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPR---GKPGQKGYAGEPGP 835
Query: 301 EGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECG 352
E G+ + + ++ GE G G+P E G+ + +G SPG G G
Sbjct: 836 E-GLKGEVGDQGNIGKIGETGPVGLP-GEVGMTGSIGEKGERGSPGPLGPQG 885
Score = 72.0 bits (175), Expect = 9e-13
Identities = 86/299 (28%), Positives = 110/299 (36%), Gaps = 63/299 (21%)
Query: 77 PRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRV 136
P ++ G GH G GE GIP G ++ SPG G G+ EG
Sbjct: 562 PPGMQGDKGLKGHPGLPGLPGEQGIPGFAG----------NIGSPGYPGRQGLAGPEGNP 611
Query: 137 WRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG--GVWR 194
P +G + SPGE G+ G P E G+ PG +G+ G R+G G +
Sbjct: 612 -GPKGAQGFIGSPGEAGQLG-PEGERGI------------PGIRGKKGFKGRQGFPGDFG 657
Query: 195 PLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLER 254
G SPG G G P G R SV G G G+P P+
Sbjct: 658 DRGPAGLDGSPGLVGGTGPPGFPG-------LRGSVGPVGPIGPAGIP-------GPMGL 703
Query: 255 RGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEG--GVWRPLERRA 312
G+ PG KG+ G T G + P PG+KG G+P G G P
Sbjct: 704 SGNKGLPGIKGDKGEQGTAGELGEP-------GYPGDKGAVGLPGPPGMRGKSGP---SG 753
Query: 313 SVASPGEKGECGVPWREG-----------GVWRPLDRRGSVASPGEKGECGVRWREGRV 360
PG +G G P EG G P G+ PG G G + EG +
Sbjct: 754 QTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPI 812
Score = 56.6 bits (135), Expect = 4e-08
Identities = 55/187 (29%), Positives = 78/187 (41%), Gaps = 30/187 (16%)
Query: 178 GQKGECGVPWREG--GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVAS--P 233
G KG+ G P G G+ P +RG PG G G+P G + S P
Sbjct: 489 GPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVP 548
Query: 234 GQKGECGVPWREGPVWRPLER--RGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGE 291
G+KG+ G+ GP ++ +G PG GE G+P G ++ SPG
Sbjct: 549 GEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAG----------NIGSPGY 598
Query: 292 KGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGEC 351
G G+ EG P + + SPGE G+ G P E G+ PG +G+
Sbjct: 599 PGRQGLAGPEGNP-GPKGAQGFIGSPGEAGQLG-PEGERGI------------PGIRGKK 644
Query: 352 GVRWREG 358
G + R+G
Sbjct: 645 GFKGRQG 651
>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
sapiens]
Length = 1818
Score = 94.0 bits (232), Expect = 2e-19
Identities = 96/316 (30%), Positives = 118/316 (37%), Gaps = 38/316 (12%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
P P PR ++ DG G + GEKGE G P +G + + R V G +GE G
Sbjct: 767 PIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGD-RGEVGQIGPRGEDGPE 825
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGV--- 185
+GR P G GEKG+ GVP G G P PG GE G
Sbjct: 826 GPKGRA-GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV 884
Query: 186 -----PWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLER-----RASVASPGQ 235
P + G P RG+ G+ G G +G P ER + V PG
Sbjct: 885 AGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP 944
Query: 236 KGECGVPWREGPVWRPLER-----RGSVASPGEKGECGVPWTEGGVWRPLERRASVASPG 290
KG G P ++G P +R +G PG G G P G P+ R PG
Sbjct: 945 KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVG-PQGPTGETGPIGERGHPGPPG 1003
Query: 291 EKGECGVPWTEG--------------GVWRPLERRASVASPGEKGECGVPWREGGVWRPL 336
GE G+P G G P R G G G P +GG P
Sbjct: 1004 PPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGE-GPQ 1062
Query: 337 DRRGSVASPGEKGECG 352
G V SPGE+G G
Sbjct: 1063 GPPGPVGSPGERGSAG 1078
Score = 90.9 bits (224), Expect = 2e-18
Identities = 94/300 (31%), Positives = 115/300 (38%), Gaps = 44/300 (14%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWT---EGQVWRPLER-----RASVASPGEKGE 126
P PR R G G A G G+ G T +G P ER + V PG KG
Sbjct: 888 PGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGP 947
Query: 127 CGVPWREGRVWRPLDR-----RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKG 181
G P ++G P R +G PG G G P G P+ R PG G
Sbjct: 948 PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVG-PQGPTGETGPIGERGHPGPPGPPG 1006
Query: 182 ECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGV 241
E G+P G + G+ PG +G G G P ER PG +G G+
Sbjct: 1007 EQGLPGAAG-------KEGAKGDPGPQGISGKDGPAGLRGFPGER----GLPGAQGAPGL 1055
Query: 242 PWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTE 301
EGP P G V SPGE+G G T G + P R PG GE G P E
Sbjct: 1056 KGGEGPQGPP----GPVGSPGERGSAG---TAGPIGLP-GRPGPQGPPGPAGEKGAPG-E 1106
Query: 302 GGVWRPLER---RASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
G P R + V PG G G P +G +G + PG+KG G + G
Sbjct: 1107 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGD-------KGEIGEPGQKGSKGDKGENG 1159
Score = 88.6 bits (218), Expect = 9e-18
Identities = 91/298 (30%), Positives = 113/298 (37%), Gaps = 57/298 (19%)
Query: 74 VPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWRE 133
V P+ R GEAG AAG G G P +G P V PG+ G G P
Sbjct: 1283 VGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP----GPVGFPGDPGPPGEPGPA 1338
Query: 134 GRVWRPLDR-----RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWR 188
G+ D+ G PG GE G P G P A G+KG G
Sbjct: 1339 GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE-GRQGEKGAKGEAGA 1397
Query: 189 EG--GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREG 246
EG G P+ +G PG +G G+P G PG G+ G P G
Sbjct: 1398 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG----------EQGLPGAAGQDGPPGPMG 1447
Query: 247 PVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWR 306
P P G PG KGE G P G + P E+ GEKG+ G+P T+G
Sbjct: 1448 PPGLP----GLKGDPGSKGEKGHPGLIGLIGPPGEQ-------GEKGDRGLPGTQG---- 1492
Query: 307 PLERRASVASPGEKGECGVPWREG-----------GVWRPLDRRGSVASPGEKGECGV 353
SPG KG+ G+P G G P +GS G+KG+ G+
Sbjct: 1493 ---------SPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGL 1541
Score = 87.0 bits (214), Expect = 3e-17
Identities = 98/317 (30%), Positives = 125/317 (39%), Gaps = 36/317 (11%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
PG P P I G G G+ G G+P +G P + S GEKG G P
Sbjct: 708 PGPQGLPGPQGPI-GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQS----GEKGALGPP 762
Query: 131 WREGRVWRPLDR--------RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGE 182
+G + P R RG S GEKGE G P +G + +R V G +GE
Sbjct: 763 GPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDR-GEVGQIGPRGE 821
Query: 183 CGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRAS-----VASPGQKG 237
G P G P G GEKG+ GVP G R + ++ + G+KG
Sbjct: 822 DG-PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKG 880
Query: 238 ECGVPWREGPVWR--PLERRGSVASPGEKGECGVPWTEGG---VWRPLER-----RASVA 287
GV + GP + P RGS + G G+ G T GG P ER + V
Sbjct: 881 ARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVG 940
Query: 288 SPGEKGECGVPWTEGGVWRPLER-----RASVASPGEKGECGVPWREGGVWRPLDRRGSV 342
PG KG G P +G P +R + PG G G P G P+ RG
Sbjct: 941 FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVG-PQGPTGETGPIGERGHP 999
Query: 343 ASPGEKGECGVRWREGR 359
PG GE G+ G+
Sbjct: 1000 GPPGPPGEQGLPGAAGK 1016
Score = 85.1 bits (209), Expect = 1e-16
Identities = 89/306 (29%), Positives = 110/306 (35%), Gaps = 48/306 (15%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWR--------PLERRASVASPG 122
P P P + G G G +G+ G P G V P+ R PG
Sbjct: 944 PKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG 1003
Query: 123 EKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGE 182
GE G+P G+ G+ PG +G G G P ER PG +G
Sbjct: 1004 PPGEQGLPGAAGK-------EGAKGDPGPQGISGKDGPAGLRGFPGER----GLPGAQGA 1052
Query: 183 CGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVP 242
G+ EG P G V SPGE+G G G RP PG GE G P
Sbjct: 1053 PGLKGGEGPQGPP----GPVGSPGERGSAGTAGPIGLPGRP----GPQGPPGPAGEKGAP 1104
Query: 243 WREGP--------------VWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVAS 288
+GP + P GS G+KGE G P +G E
Sbjct: 1105 GEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGE-NGPPGP 1163
Query: 289 PGEKGECGVPWTEGGVWRPLER--RASVASPGEKGECGVPWREGGVWRPLDRRGSVASPG 346
PG +G G P GG P R + G++G G P G P+ +G PG
Sbjct: 1164 PGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG----PIGLQGLPGPPG 1219
Query: 347 EKGECG 352
EKGE G
Sbjct: 1220 EKGENG 1225
Score = 84.7 bits (208), Expect = 1e-16
Identities = 93/324 (28%), Positives = 121/324 (37%), Gaps = 56/324 (17%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTE---------GQVWRPLERRASVAS----- 120
P P L G G ++G KGE G P + G +P +R A
Sbjct: 543 PGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGM 602
Query: 121 PGEKGECGVPWREGRVWRPLDR-----RGSVASPGEKGECGVPWREG-----------GV 164
PGE G G +G P D+ RG PG G+ G+ +G G
Sbjct: 603 PGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGP 662
Query: 165 WRPLERRASVASPGQKGECGVPWREG--GVWRPLERRGSVASPGEKGECGVPWREGRVWR 222
L R + +PGQ G GV G G P G G G G+P +G +
Sbjct: 663 RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGP 722
Query: 223 PLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLER 282
P E+ G+ G G+P +GP P G GEKG G P +G + P R
Sbjct: 723 PGEK----GPQGKPGLAGLPGADGPPGHP----GKEGQSGEKGALGPPGPQGPIGYPGPR 774
Query: 283 --------RASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWR 334
R S GEKGE G P +G + +R GE G+ G P E G
Sbjct: 775 GVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDR-------GEVGQIG-PRGEDGPEG 826
Query: 335 PLDRRGSVASPGEKGECGVRWREG 358
P R G PG G+ G + + G
Sbjct: 827 PKGRAGPTGDPGPSGQAGEKGKLG 850
Score = 84.0 bits (206), Expect = 2e-16
Identities = 96/314 (30%), Positives = 118/314 (37%), Gaps = 43/314 (13%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAA---GEKGECGIPWTEGQVWRPLER--------RASVA 119
P P L DG GH GEKG G P +G + P R R
Sbjct: 728 PQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKG 787
Query: 120 SPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQ 179
S GEKGE G P +G + D RG V G +GE G P G P G+
Sbjct: 788 SKGEKGEDGFPGFKGDMGLKGD-RGEVGQIGPRGEDG-PEGPKGRAGPTGDPGPSGQAGE 845
Query: 180 KGECGVPWREGGVWRPLERRGSVASP------GEKGECGVPWREGRVWR-----PLERRA 228
KG+ GVP G R +GS P GEKG GV + G + P R
Sbjct: 846 KGKLGVPGLPGYPGRQ-GPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRG 904
Query: 229 SVASPGQKGECGVPWREGPVWRPLER-----RGSVASPGEKGECGVPWTEGGVWRPLER- 282
+ G+ G G +GP P ER +G V PG KG G P +G P +R
Sbjct: 905 ARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRG 964
Query: 283 ----RASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDR 338
+ PG G G P G P+ R PG GE G+P G +
Sbjct: 965 ETGFQGKTGPPGPGGVVG-PQGPTGETGPIGERGHPGPPGPPGEQGLPGAAG-------K 1016
Query: 339 RGSVASPGEKGECG 352
G+ PG +G G
Sbjct: 1017 EGAKGDPGPQGISG 1030
Score = 80.9 bits (198), Expect = 2e-15
Identities = 80/277 (28%), Positives = 103/277 (37%), Gaps = 70/277 (25%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
G AG G+KGE G P G P PG++G G EGR +G
Sbjct: 1336 GPAGQDGVGGDKGEDGDPGQPGPPG-PSGEAGPPGPPGKRGPPGAAGAEGR-------QG 1387
Query: 145 SVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVAS 204
+ GE G G P + G P+ + PG +G G+P G P G
Sbjct: 1388 EKGAKGEAGAEGPPGKTG----PVGPQGPAGKPGPEGLRGIPGPVGEQGLP-GAAGQDGP 1442
Query: 205 PGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEK 264
PG G G+P +G PG KGE G P G + P E+ GEK
Sbjct: 1443 PGPMGPPGLPGLKG-------------DPGSKGEKGHPGLIGLIGPPGEQ-------GEK 1482
Query: 265 GECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEG-----------GVWRPLERRAS 313
G+ G+P T+G SPG KG+ G+P G G P + S
Sbjct: 1483 GDRGLPGTQG-------------SPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGS 1529
Query: 314 VASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGE 350
G+KG+ G+P G SPG GE
Sbjct: 1530 TGPAGQKGDSGLP-------------GPPGSPGPPGE 1553
Score = 74.7 bits (182), Expect = 1e-13
Identities = 86/300 (28%), Positives = 106/300 (35%), Gaps = 32/300 (10%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
P P L+ + G G G+ G G P G R G G G P G
Sbjct: 1206 PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGP-------RGPQGPNGADGPQGPPGSVG 1258
Query: 135 RVWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGVPWREG-- 190
V G V GE GE G P G GV P R G G G P +G
Sbjct: 1259 SV-------GGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPP 1311
Query: 191 GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWR 250
G P G V PG+ G G P G+ ++ PGQ G G GP
Sbjct: 1312 GDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGED-GDPGQPGPPGPSGEAGPPGP 1370
Query: 251 PLER-----RGSVASPGEKGECGVPWTEG--GVWRPLERRASVASPGEKGECGVPWTEGG 303
P +R G+ GEKG G EG G P+ + PG +G G+P G
Sbjct: 1371 PGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGE 1430
Query: 304 VWRPLERRASVASPGEKGECGVPWREGGVWRPLDRR-----GSVASPGEKGECGVRWREG 358
P PG G G+P +G ++ G + PGE+GE G R G
Sbjct: 1431 QGLP-GAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1489
Score = 70.5 bits (171), Expect = 2e-12
Identities = 82/279 (29%), Positives = 98/279 (35%), Gaps = 36/279 (12%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
P PR G+ G G++G G P G P+ + PGEKGE G G
Sbjct: 1182 PGPR------GQQGMFGQKGDEGARGFPGPPG----PIGLQGLPGPPGEKGENGDVGPMG 1231
Query: 135 RVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWR 194
P RG G G G P G V E+ PG+ G G P E GV
Sbjct: 1232 PPGPP-GPRGPQGPNGADGPQGPPGSVGSVGGVGEK----GEPGEAGNPGPPG-EAGVGG 1285
Query: 195 PLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLER 254
P RG G G G P +G G G G P GP P
Sbjct: 1286 PKGERGEKGEAGPPGAAGPPGAKG-------PPGDDGPKGNPGPVGFPGDPGPPGEP-GP 1337
Query: 255 RGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASV 314
G G+KGE G P G P PG G+ G P G R E+ A
Sbjct: 1338 AGQDGVGGDKGEDGDPGQPG----PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAK- 1392
Query: 315 ASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGV 353
GE G G P + G P+ +G PG +G G+
Sbjct: 1393 ---GEAGAEGPPGKTG----PVGPQGPAGKPGPEGLRGI 1424
Score = 70.5 bits (171), Expect = 2e-12
Identities = 65/220 (29%), Positives = 84/220 (38%), Gaps = 47/220 (21%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWR--PLERRASVASPGEKGECGVPWR 132
P P R G AG GEKG G EG + P+ + PG +G G+P
Sbjct: 1368 PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP 1427
Query: 133 EGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGV 192
G P G PG G G+P +G PG KGE G P G +
Sbjct: 1428 VGEQGLP-GAAGQDGPPGPMGPPGLPGLKG-------------DPGSKGEKGHPGLIGLI 1473
Query: 193 WRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRP- 251
P E+ GEKG+ G+P +G SPG KG+ G+P GP+ P
Sbjct: 1474 GPPGEQ-------GEKGDRGLPGTQG-------------SPGAKGDGGIPGPAGPLGPPG 1513
Query: 252 ----------LERRGSVASPGEKGECGVPWTEGGVWRPLE 281
+GS G+KG+ G+P G P E
Sbjct: 1514 PPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1553
Score = 53.5 bits (127), Expect = 3e-07
Identities = 80/345 (23%), Positives = 119/345 (34%), Gaps = 77/345 (22%)
Query: 53 DQMGSVEKLTTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPL 112
+++ + E LT + S + S + IDG G+ GE + +P
Sbjct: 347 EEIFTEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKP- 405
Query: 113 ERRASVASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRA 172
+ P E+ GVP ++ G+ G+KGE
Sbjct: 406 -----TSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGE-----------------P 443
Query: 173 SVASPGQKGECGVPWREG--GVWRPLERRGSVASPGEKGECGVPWREG------------ 218
+V PG E G P G G+ P +G PG+ G+ G P R G
Sbjct: 444 AVVEPGMLVE-GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPG 502
Query: 219 -----------------------RVWRPLERRASVASPGQKGECGVPWREGPVWRPLERR 255
+ + ++A +A G G G+ R GPV
Sbjct: 503 TMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPV------- 555
Query: 256 GSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASVA 315
G S G KGE G P +G P + G+ G+ G P +GG P E A
Sbjct: 556 GGPGSSGAKGESGDPGPQG----PRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAK-- 609
Query: 316 SPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREGRV 360
G++G G+P G RG PG G+ G+R +G +
Sbjct: 610 --GDRGFDGLPGLPGDKGH-RGERGPQGPPGPPGDDGMRGEDGEI 651
>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
sapiens]
Length = 1767
Score = 94.0 bits (232), Expect = 2e-19
Identities = 96/316 (30%), Positives = 118/316 (37%), Gaps = 38/316 (12%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
P P PR ++ DG G + GEKGE G P +G + + R V G +GE G
Sbjct: 716 PIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGD-RGEVGQIGPRGEDGPE 774
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGV--- 185
+GR P G GEKG+ GVP G G P PG GE G
Sbjct: 775 GPKGRA-GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV 833
Query: 186 -----PWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLER-----RASVASPGQ 235
P + G P RG+ G+ G G +G P ER + V PG
Sbjct: 834 AGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP 893
Query: 236 KGECGVPWREGPVWRPLER-----RGSVASPGEKGECGVPWTEGGVWRPLERRASVASPG 290
KG G P ++G P +R +G PG G G P G P+ R PG
Sbjct: 894 KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVG-PQGPTGETGPIGERGHPGPPG 952
Query: 291 EKGECGVPWTEG--------------GVWRPLERRASVASPGEKGECGVPWREGGVWRPL 336
GE G+P G G P R G G G P +GG P
Sbjct: 953 PPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGE-GPQ 1011
Query: 337 DRRGSVASPGEKGECG 352
G V SPGE+G G
Sbjct: 1012 GPPGPVGSPGERGSAG 1027
Score = 90.9 bits (224), Expect = 2e-18
Identities = 94/300 (31%), Positives = 115/300 (38%), Gaps = 44/300 (14%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWT---EGQVWRPLER-----RASVASPGEKGE 126
P PR R G G A G G+ G T +G P ER + V PG KG
Sbjct: 837 PGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGP 896
Query: 127 CGVPWREGRVWRPLDR-----RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKG 181
G P ++G P R +G PG G G P G P+ R PG G
Sbjct: 897 PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVG-PQGPTGETGPIGERGHPGPPGPPG 955
Query: 182 ECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGV 241
E G+P G + G+ PG +G G G P ER PG +G G+
Sbjct: 956 EQGLPGAAG-------KEGAKGDPGPQGISGKDGPAGLRGFPGER----GLPGAQGAPGL 1004
Query: 242 PWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTE 301
EGP P G V SPGE+G G T G + P R PG GE G P E
Sbjct: 1005 KGGEGPQGPP----GPVGSPGERGSAG---TAGPIGLP-GRPGPQGPPGPAGEKGAPG-E 1055
Query: 302 GGVWRPLER---RASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
G P R + V PG G G P +G +G + PG+KG G + G
Sbjct: 1056 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGD-------KGEIGEPGQKGSKGDKGENG 1108
Score = 88.6 bits (218), Expect = 9e-18
Identities = 91/298 (30%), Positives = 113/298 (37%), Gaps = 57/298 (19%)
Query: 74 VPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWRE 133
V P+ R GEAG AAG G G P +G P V PG+ G G P
Sbjct: 1232 VGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP----GPVGFPGDPGPPGEPGPA 1287
Query: 134 GRVWRPLDR-----RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWR 188
G+ D+ G PG GE G P G P A G+KG G
Sbjct: 1288 GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE-GRQGEKGAKGEAGA 1346
Query: 189 EG--GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREG 246
EG G P+ +G PG +G G+P G PG G+ G P G
Sbjct: 1347 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG----------EQGLPGAAGQDGPPGPMG 1396
Query: 247 PVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWR 306
P P G PG KGE G P G + P E+ GEKG+ G+P T+G
Sbjct: 1397 PPGLP----GLKGDPGSKGEKGHPGLIGLIGPPGEQ-------GEKGDRGLPGTQG---- 1441
Query: 307 PLERRASVASPGEKGECGVPWREG-----------GVWRPLDRRGSVASPGEKGECGV 353
SPG KG+ G+P G G P +GS G+KG+ G+
Sbjct: 1442 ---------SPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGL 1490
Score = 87.0 bits (214), Expect = 3e-17
Identities = 98/317 (30%), Positives = 125/317 (39%), Gaps = 36/317 (11%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
PG P P I G G G+ G G+P +G P + S GEKG G P
Sbjct: 657 PGPQGLPGPQGPI-GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQS----GEKGALGPP 711
Query: 131 WREGRVWRPLDR--------RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGE 182
+G + P R RG S GEKGE G P +G + +R V G +GE
Sbjct: 712 GPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDR-GEVGQIGPRGE 770
Query: 183 CGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRAS-----VASPGQKG 237
G P G P G GEKG+ GVP G R + ++ + G+KG
Sbjct: 771 DG-PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKG 829
Query: 238 ECGVPWREGPVWR--PLERRGSVASPGEKGECGVPWTEGG---VWRPLER-----RASVA 287
GV + GP + P RGS + G G+ G T GG P ER + V
Sbjct: 830 ARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVG 889
Query: 288 SPGEKGECGVPWTEGGVWRPLER-----RASVASPGEKGECGVPWREGGVWRPLDRRGSV 342
PG KG G P +G P +R + PG G G P G P+ RG
Sbjct: 890 FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVG-PQGPTGETGPIGERGHP 948
Query: 343 ASPGEKGECGVRWREGR 359
PG GE G+ G+
Sbjct: 949 GPPGPPGEQGLPGAAGK 965
Score = 85.1 bits (209), Expect = 1e-16
Identities = 89/306 (29%), Positives = 110/306 (35%), Gaps = 48/306 (15%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWR--------PLERRASVASPG 122
P P P + G G G +G+ G P G V P+ R PG
Sbjct: 893 PKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG 952
Query: 123 EKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGE 182
GE G+P G+ G+ PG +G G G P ER PG +G
Sbjct: 953 PPGEQGLPGAAGK-------EGAKGDPGPQGISGKDGPAGLRGFPGER----GLPGAQGA 1001
Query: 183 CGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVP 242
G+ EG P G V SPGE+G G G RP PG GE G P
Sbjct: 1002 PGLKGGEGPQGPP----GPVGSPGERGSAGTAGPIGLPGRP----GPQGPPGPAGEKGAP 1053
Query: 243 WREGP--------------VWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVAS 288
+GP + P GS G+KGE G P +G E
Sbjct: 1054 GEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGE-NGPPGP 1112
Query: 289 PGEKGECGVPWTEGGVWRPLER--RASVASPGEKGECGVPWREGGVWRPLDRRGSVASPG 346
PG +G G P GG P R + G++G G P G P+ +G PG
Sbjct: 1113 PGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG----PIGLQGLPGPPG 1168
Query: 347 EKGECG 352
EKGE G
Sbjct: 1169 EKGENG 1174
Score = 84.7 bits (208), Expect = 1e-16
Identities = 93/324 (28%), Positives = 121/324 (37%), Gaps = 56/324 (17%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTE---------GQVWRPLERRASVAS----- 120
P P L G G ++G KGE G P + G +P +R A
Sbjct: 492 PGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGM 551
Query: 121 PGEKGECGVPWREGRVWRPLDR-----RGSVASPGEKGECGVPWREG-----------GV 164
PGE G G +G P D+ RG PG G+ G+ +G G
Sbjct: 552 PGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGP 611
Query: 165 WRPLERRASVASPGQKGECGVPWREG--GVWRPLERRGSVASPGEKGECGVPWREGRVWR 222
L R + +PGQ G GV G G P G G G G+P +G +
Sbjct: 612 RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGP 671
Query: 223 PLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLER 282
P E+ G+ G G+P +GP P G GEKG G P +G + P R
Sbjct: 672 PGEK----GPQGKPGLAGLPGADGPPGHP----GKEGQSGEKGALGPPGPQGPIGYPGPR 723
Query: 283 --------RASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWR 334
R S GEKGE G P +G + +R GE G+ G P E G
Sbjct: 724 GVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDR-------GEVGQIG-PRGEDGPEG 775
Query: 335 PLDRRGSVASPGEKGECGVRWREG 358
P R G PG G+ G + + G
Sbjct: 776 PKGRAGPTGDPGPSGQAGEKGKLG 799
Score = 84.0 bits (206), Expect = 2e-16
Identities = 96/314 (30%), Positives = 118/314 (37%), Gaps = 43/314 (13%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAA---GEKGECGIPWTEGQVWRPLER--------RASVA 119
P P L DG GH GEKG G P +G + P R R
Sbjct: 677 PQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKG 736
Query: 120 SPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQ 179
S GEKGE G P +G + D RG V G +GE G P G P G+
Sbjct: 737 SKGEKGEDGFPGFKGDMGLKGD-RGEVGQIGPRGEDG-PEGPKGRAGPTGDPGPSGQAGE 794
Query: 180 KGECGVPWREGGVWRPLERRGSVASP------GEKGECGVPWREGRVWR-----PLERRA 228
KG+ GVP G R +GS P GEKG GV + G + P R
Sbjct: 795 KGKLGVPGLPGYPGRQ-GPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRG 853
Query: 229 SVASPGQKGECGVPWREGPVWRPLER-----RGSVASPGEKGECGVPWTEGGVWRPLER- 282
+ G+ G G +GP P ER +G V PG KG G P +G P +R
Sbjct: 854 ARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRG 913
Query: 283 ----RASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDR 338
+ PG G G P G P+ R PG GE G+P G +
Sbjct: 914 ETGFQGKTGPPGPGGVVG-PQGPTGETGPIGERGHPGPPGPPGEQGLPGAAG-------K 965
Query: 339 RGSVASPGEKGECG 352
G+ PG +G G
Sbjct: 966 EGAKGDPGPQGISG 979
Score = 80.9 bits (198), Expect = 2e-15
Identities = 80/277 (28%), Positives = 103/277 (37%), Gaps = 70/277 (25%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
G AG G+KGE G P G P PG++G G EGR +G
Sbjct: 1285 GPAGQDGVGGDKGEDGDPGQPGPPG-PSGEAGPPGPPGKRGPPGAAGAEGR-------QG 1336
Query: 145 SVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVAS 204
+ GE G G P + G P+ + PG +G G+P G P G
Sbjct: 1337 EKGAKGEAGAEGPPGKTG----PVGPQGPAGKPGPEGLRGIPGPVGEQGLP-GAAGQDGP 1391
Query: 205 PGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEK 264
PG G G+P +G PG KGE G P G + P E+ GEK
Sbjct: 1392 PGPMGPPGLPGLKG-------------DPGSKGEKGHPGLIGLIGPPGEQ-------GEK 1431
Query: 265 GECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEG-----------GVWRPLERRAS 313
G+ G+P T+G SPG KG+ G+P G G P + S
Sbjct: 1432 GDRGLPGTQG-------------SPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGS 1478
Query: 314 VASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGE 350
G+KG+ G+P G SPG GE
Sbjct: 1479 TGPAGQKGDSGLP-------------GPPGSPGPPGE 1502
Score = 74.7 bits (182), Expect = 1e-13
Identities = 86/300 (28%), Positives = 106/300 (35%), Gaps = 32/300 (10%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
P P L+ + G G G+ G G P G R G G G P G
Sbjct: 1155 PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGP-------RGPQGPNGADGPQGPPGSVG 1207
Query: 135 RVWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGVPWREG-- 190
V G V GE GE G P G GV P R G G G P +G
Sbjct: 1208 SV-------GGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPP 1260
Query: 191 GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWR 250
G P G V PG+ G G P G+ ++ PGQ G G GP
Sbjct: 1261 GDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGED-GDPGQPGPPGPSGEAGPPGP 1319
Query: 251 PLER-----RGSVASPGEKGECGVPWTEG--GVWRPLERRASVASPGEKGECGVPWTEGG 303
P +R G+ GEKG G EG G P+ + PG +G G+P G
Sbjct: 1320 PGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGE 1379
Query: 304 VWRPLERRASVASPGEKGECGVPWREGGVWRPLDRR-----GSVASPGEKGECGVRWREG 358
P PG G G+P +G ++ G + PGE+GE G R G
Sbjct: 1380 QGLP-GAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1438
Score = 70.5 bits (171), Expect = 2e-12
Identities = 82/279 (29%), Positives = 98/279 (35%), Gaps = 36/279 (12%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
P PR G+ G G++G G P G P+ + PGEKGE G G
Sbjct: 1131 PGPR------GQQGMFGQKGDEGARGFPGPPG----PIGLQGLPGPPGEKGENGDVGPMG 1180
Query: 135 RVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWR 194
P RG G G G P G V E+ PG+ G G P E GV
Sbjct: 1181 PPGPP-GPRGPQGPNGADGPQGPPGSVGSVGGVGEK----GEPGEAGNPGPPG-EAGVGG 1234
Query: 195 PLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLER 254
P RG G G G P +G G G G P GP P
Sbjct: 1235 PKGERGEKGEAGPPGAAGPPGAKG-------PPGDDGPKGNPGPVGFPGDPGPPGEP-GP 1286
Query: 255 RGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASV 314
G G+KGE G P G P PG G+ G P G R E+ A
Sbjct: 1287 AGQDGVGGDKGEDGDPGQPG----PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAK- 1341
Query: 315 ASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGV 353
GE G G P + G P+ +G PG +G G+
Sbjct: 1342 ---GEAGAEGPPGKTG----PVGPQGPAGKPGPEGLRGI 1373
Score = 70.5 bits (171), Expect = 2e-12
Identities = 65/220 (29%), Positives = 84/220 (38%), Gaps = 47/220 (21%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWR--PLERRASVASPGEKGECGVPWR 132
P P R G AG GEKG G EG + P+ + PG +G G+P
Sbjct: 1317 PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP 1376
Query: 133 EGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGV 192
G P G PG G G+P +G PG KGE G P G +
Sbjct: 1377 VGEQGLP-GAAGQDGPPGPMGPPGLPGLKG-------------DPGSKGEKGHPGLIGLI 1422
Query: 193 WRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRP- 251
P E+ GEKG+ G+P +G SPG KG+ G+P GP+ P
Sbjct: 1423 GPPGEQ-------GEKGDRGLPGTQG-------------SPGAKGDGGIPGPAGPLGPPG 1462
Query: 252 ----------LERRGSVASPGEKGECGVPWTEGGVWRPLE 281
+GS G+KG+ G+P G P E
Sbjct: 1463 PPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1502
Score = 53.5 bits (127), Expect = 3e-07
Identities = 80/345 (23%), Positives = 119/345 (34%), Gaps = 77/345 (22%)
Query: 53 DQMGSVEKLTTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPL 112
+++ + E LT + S + S + IDG G+ GE + +P
Sbjct: 296 EEIFTEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKP- 354
Query: 113 ERRASVASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRA 172
+ P E+ GVP ++ G+ G+KGE
Sbjct: 355 -----TSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGE-----------------P 392
Query: 173 SVASPGQKGECGVPWREG--GVWRPLERRGSVASPGEKGECGVPWREG------------ 218
+V PG E G P G G+ P +G PG+ G+ G P R G
Sbjct: 393 AVVEPGMLVE-GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPG 451
Query: 219 -----------------------RVWRPLERRASVASPGQKGECGVPWREGPVWRPLERR 255
+ + ++A +A G G G+ R GPV
Sbjct: 452 TMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPV------- 504
Query: 256 GSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASVA 315
G S G KGE G P +G P + G+ G+ G P +GG P E A
Sbjct: 505 GGPGSSGAKGESGDPGPQG----PRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAK-- 558
Query: 316 SPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREGRV 360
G++G G+P G RG PG G+ G+R +G +
Sbjct: 559 --GDRGFDGLPGLPGDKGH-RGERGPQGPPGPPGDDGMRGEDGEI 600
>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
sapiens]
Length = 1806
Score = 94.0 bits (232), Expect = 2e-19
Identities = 96/316 (30%), Positives = 118/316 (37%), Gaps = 38/316 (12%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
P P PR ++ DG G + GEKGE G P +G + + R V G +GE G
Sbjct: 755 PIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGD-RGEVGQIGPRGEDGPE 813
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGV--- 185
+GR P G GEKG+ GVP G G P PG GE G
Sbjct: 814 GPKGRA-GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV 872
Query: 186 -----PWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLER-----RASVASPGQ 235
P + G P RG+ G+ G G +G P ER + V PG
Sbjct: 873 AGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP 932
Query: 236 KGECGVPWREGPVWRPLER-----RGSVASPGEKGECGVPWTEGGVWRPLERRASVASPG 290
KG G P ++G P +R +G PG G G P G P+ R PG
Sbjct: 933 KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVG-PQGPTGETGPIGERGHPGPPG 991
Query: 291 EKGECGVPWTEG--------------GVWRPLERRASVASPGEKGECGVPWREGGVWRPL 336
GE G+P G G P R G G G P +GG P
Sbjct: 992 PPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGE-GPQ 1050
Query: 337 DRRGSVASPGEKGECG 352
G V SPGE+G G
Sbjct: 1051 GPPGPVGSPGERGSAG 1066
Score = 90.9 bits (224), Expect = 2e-18
Identities = 94/300 (31%), Positives = 115/300 (38%), Gaps = 44/300 (14%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWT---EGQVWRPLER-----RASVASPGEKGE 126
P PR R G G A G G+ G T +G P ER + V PG KG
Sbjct: 876 PGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGP 935
Query: 127 CGVPWREGRVWRPLDR-----RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKG 181
G P ++G P R +G PG G G P G P+ R PG G
Sbjct: 936 PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVG-PQGPTGETGPIGERGHPGPPGPPG 994
Query: 182 ECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGV 241
E G+P G + G+ PG +G G G P ER PG +G G+
Sbjct: 995 EQGLPGAAG-------KEGAKGDPGPQGISGKDGPAGLRGFPGER----GLPGAQGAPGL 1043
Query: 242 PWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTE 301
EGP P G V SPGE+G G T G + P R PG GE G P E
Sbjct: 1044 KGGEGPQGPP----GPVGSPGERGSAG---TAGPIGLP-GRPGPQGPPGPAGEKGAPG-E 1094
Query: 302 GGVWRPLER---RASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
G P R + V PG G G P +G +G + PG+KG G + G
Sbjct: 1095 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGD-------KGEIGEPGQKGSKGDKGENG 1147
Score = 88.6 bits (218), Expect = 9e-18
Identities = 91/298 (30%), Positives = 113/298 (37%), Gaps = 57/298 (19%)
Query: 74 VPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWRE 133
V P+ R GEAG AAG G G P +G P V PG+ G G P
Sbjct: 1271 VGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP----GPVGFPGDPGPPGEPGPA 1326
Query: 134 GRVWRPLDR-----RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWR 188
G+ D+ G PG GE G P G P A G+KG G
Sbjct: 1327 GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE-GRQGEKGAKGEAGA 1385
Query: 189 EG--GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREG 246
EG G P+ +G PG +G G+P G PG G+ G P G
Sbjct: 1386 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG----------EQGLPGAAGQDGPPGPMG 1435
Query: 247 PVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWR 306
P P G PG KGE G P G + P E+ GEKG+ G+P T+G
Sbjct: 1436 PPGLP----GLKGDPGSKGEKGHPGLIGLIGPPGEQ-------GEKGDRGLPGTQG---- 1480
Query: 307 PLERRASVASPGEKGECGVPWREG-----------GVWRPLDRRGSVASPGEKGECGV 353
SPG KG+ G+P G G P +GS G+KG+ G+
Sbjct: 1481 ---------SPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGL 1529
Score = 87.0 bits (214), Expect = 3e-17
Identities = 98/317 (30%), Positives = 125/317 (39%), Gaps = 36/317 (11%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
PG P P I G G G+ G G+P +G P + S GEKG G P
Sbjct: 696 PGPQGLPGPQGPI-GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQS----GEKGALGPP 750
Query: 131 WREGRVWRPLDR--------RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGE 182
+G + P R RG S GEKGE G P +G + +R V G +GE
Sbjct: 751 GPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDR-GEVGQIGPRGE 809
Query: 183 CGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRAS-----VASPGQKG 237
G P G P G GEKG+ GVP G R + ++ + G+KG
Sbjct: 810 DG-PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKG 868
Query: 238 ECGVPWREGPVWR--PLERRGSVASPGEKGECGVPWTEGG---VWRPLER-----RASVA 287
GV + GP + P RGS + G G+ G T GG P ER + V
Sbjct: 869 ARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVG 928
Query: 288 SPGEKGECGVPWTEGGVWRPLER-----RASVASPGEKGECGVPWREGGVWRPLDRRGSV 342
PG KG G P +G P +R + PG G G P G P+ RG
Sbjct: 929 FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVG-PQGPTGETGPIGERGHP 987
Query: 343 ASPGEKGECGVRWREGR 359
PG GE G+ G+
Sbjct: 988 GPPGPPGEQGLPGAAGK 1004
Score = 85.1 bits (209), Expect = 1e-16
Identities = 89/306 (29%), Positives = 110/306 (35%), Gaps = 48/306 (15%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWR--------PLERRASVASPG 122
P P P + G G G +G+ G P G V P+ R PG
Sbjct: 932 PKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG 991
Query: 123 EKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGE 182
GE G+P G+ G+ PG +G G G P ER PG +G
Sbjct: 992 PPGEQGLPGAAGK-------EGAKGDPGPQGISGKDGPAGLRGFPGER----GLPGAQGA 1040
Query: 183 CGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVP 242
G+ EG P G V SPGE+G G G RP PG GE G P
Sbjct: 1041 PGLKGGEGPQGPP----GPVGSPGERGSAGTAGPIGLPGRP----GPQGPPGPAGEKGAP 1092
Query: 243 WREGP--------------VWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVAS 288
+GP + P GS G+KGE G P +G E
Sbjct: 1093 GEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGE-NGPPGP 1151
Query: 289 PGEKGECGVPWTEGGVWRPLER--RASVASPGEKGECGVPWREGGVWRPLDRRGSVASPG 346
PG +G G P GG P R + G++G G P G P+ +G PG
Sbjct: 1152 PGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG----PIGLQGLPGPPG 1207
Query: 347 EKGECG 352
EKGE G
Sbjct: 1208 EKGENG 1213
Score = 84.7 bits (208), Expect = 1e-16
Identities = 93/324 (28%), Positives = 121/324 (37%), Gaps = 56/324 (17%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTE---------GQVWRPLERRASVAS----- 120
P P L G G ++G KGE G P + G +P +R A
Sbjct: 531 PGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGM 590
Query: 121 PGEKGECGVPWREGRVWRPLDR-----RGSVASPGEKGECGVPWREG-----------GV 164
PGE G G +G P D+ RG PG G+ G+ +G G
Sbjct: 591 PGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGP 650
Query: 165 WRPLERRASVASPGQKGECGVPWREG--GVWRPLERRGSVASPGEKGECGVPWREGRVWR 222
L R + +PGQ G GV G G P G G G G+P +G +
Sbjct: 651 RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGP 710
Query: 223 PLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLER 282
P E+ G+ G G+P +GP P G GEKG G P +G + P R
Sbjct: 711 PGEK----GPQGKPGLAGLPGADGPPGHP----GKEGQSGEKGALGPPGPQGPIGYPGPR 762
Query: 283 --------RASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWR 334
R S GEKGE G P +G + +R GE G+ G P E G
Sbjct: 763 GVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDR-------GEVGQIG-PRGEDGPEG 814
Query: 335 PLDRRGSVASPGEKGECGVRWREG 358
P R G PG G+ G + + G
Sbjct: 815 PKGRAGPTGDPGPSGQAGEKGKLG 838
Score = 84.0 bits (206), Expect = 2e-16
Identities = 96/314 (30%), Positives = 118/314 (37%), Gaps = 43/314 (13%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAA---GEKGECGIPWTEGQVWRPLER--------RASVA 119
P P L DG GH GEKG G P +G + P R R
Sbjct: 716 PQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKG 775
Query: 120 SPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQ 179
S GEKGE G P +G + D RG V G +GE G P G P G+
Sbjct: 776 SKGEKGEDGFPGFKGDMGLKGD-RGEVGQIGPRGEDG-PEGPKGRAGPTGDPGPSGQAGE 833
Query: 180 KGECGVPWREGGVWRPLERRGSVASP------GEKGECGVPWREGRVWR-----PLERRA 228
KG+ GVP G R +GS P GEKG GV + G + P R
Sbjct: 834 KGKLGVPGLPGYPGRQ-GPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRG 892
Query: 229 SVASPGQKGECGVPWREGPVWRPLER-----RGSVASPGEKGECGVPWTEGGVWRPLER- 282
+ G+ G G +GP P ER +G V PG KG G P +G P +R
Sbjct: 893 ARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRG 952
Query: 283 ----RASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDR 338
+ PG G G P G P+ R PG GE G+P G +
Sbjct: 953 ETGFQGKTGPPGPGGVVG-PQGPTGETGPIGERGHPGPPGPPGEQGLPGAAG-------K 1004
Query: 339 RGSVASPGEKGECG 352
G+ PG +G G
Sbjct: 1005 EGAKGDPGPQGISG 1018
Score = 80.9 bits (198), Expect = 2e-15
Identities = 80/277 (28%), Positives = 103/277 (37%), Gaps = 70/277 (25%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
G AG G+KGE G P G P PG++G G EGR +G
Sbjct: 1324 GPAGQDGVGGDKGEDGDPGQPGPPG-PSGEAGPPGPPGKRGPPGAAGAEGR-------QG 1375
Query: 145 SVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVAS 204
+ GE G G P + G P+ + PG +G G+P G P G
Sbjct: 1376 EKGAKGEAGAEGPPGKTG----PVGPQGPAGKPGPEGLRGIPGPVGEQGLP-GAAGQDGP 1430
Query: 205 PGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEK 264
PG G G+P +G PG KGE G P G + P E+ GEK
Sbjct: 1431 PGPMGPPGLPGLKG-------------DPGSKGEKGHPGLIGLIGPPGEQ-------GEK 1470
Query: 265 GECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEG-----------GVWRPLERRAS 313
G+ G+P T+G SPG KG+ G+P G G P + S
Sbjct: 1471 GDRGLPGTQG-------------SPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGS 1517
Query: 314 VASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGE 350
G+KG+ G+P G SPG GE
Sbjct: 1518 TGPAGQKGDSGLP-------------GPPGSPGPPGE 1541
Score = 74.7 bits (182), Expect = 1e-13
Identities = 86/300 (28%), Positives = 106/300 (35%), Gaps = 32/300 (10%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
P P L+ + G G G+ G G P G R G G G P G
Sbjct: 1194 PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGP-------RGPQGPNGADGPQGPPGSVG 1246
Query: 135 RVWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGVPWREG-- 190
V G V GE GE G P G GV P R G G G P +G
Sbjct: 1247 SV-------GGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPP 1299
Query: 191 GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWR 250
G P G V PG+ G G P G+ ++ PGQ G G GP
Sbjct: 1300 GDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGED-GDPGQPGPPGPSGEAGPPGP 1358
Query: 251 PLER-----RGSVASPGEKGECGVPWTEG--GVWRPLERRASVASPGEKGECGVPWTEGG 303
P +R G+ GEKG G EG G P+ + PG +G G+P G
Sbjct: 1359 PGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGE 1418
Query: 304 VWRPLERRASVASPGEKGECGVPWREGGVWRPLDRR-----GSVASPGEKGECGVRWREG 358
P PG G G+P +G ++ G + PGE+GE G R G
Sbjct: 1419 QGLP-GAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1477
Score = 70.5 bits (171), Expect = 2e-12
Identities = 82/279 (29%), Positives = 98/279 (35%), Gaps = 36/279 (12%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
P PR G+ G G++G G P G P+ + PGEKGE G G
Sbjct: 1170 PGPR------GQQGMFGQKGDEGARGFPGPPG----PIGLQGLPGPPGEKGENGDVGPMG 1219
Query: 135 RVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWR 194
P RG G G G P G V E+ PG+ G G P E GV
Sbjct: 1220 PPGPP-GPRGPQGPNGADGPQGPPGSVGSVGGVGEK----GEPGEAGNPGPPG-EAGVGG 1273
Query: 195 PLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLER 254
P RG G G G P +G G G G P GP P
Sbjct: 1274 PKGERGEKGEAGPPGAAGPPGAKG-------PPGDDGPKGNPGPVGFPGDPGPPGEP-GP 1325
Query: 255 RGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASV 314
G G+KGE G P G P PG G+ G P G R E+ A
Sbjct: 1326 AGQDGVGGDKGEDGDPGQPG----PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAK- 1380
Query: 315 ASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGV 353
GE G G P + G P+ +G PG +G G+
Sbjct: 1381 ---GEAGAEGPPGKTG----PVGPQGPAGKPGPEGLRGI 1412
Score = 70.5 bits (171), Expect = 2e-12
Identities = 65/220 (29%), Positives = 84/220 (38%), Gaps = 47/220 (21%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWR--PLERRASVASPGEKGECGVPWR 132
P P R G AG GEKG G EG + P+ + PG +G G+P
Sbjct: 1356 PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP 1415
Query: 133 EGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGV 192
G P G PG G G+P +G PG KGE G P G +
Sbjct: 1416 VGEQGLP-GAAGQDGPPGPMGPPGLPGLKG-------------DPGSKGEKGHPGLIGLI 1461
Query: 193 WRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRP- 251
P E+ GEKG+ G+P +G SPG KG+ G+P GP+ P
Sbjct: 1462 GPPGEQ-------GEKGDRGLPGTQG-------------SPGAKGDGGIPGPAGPLGPPG 1501
Query: 252 ----------LERRGSVASPGEKGECGVPWTEGGVWRPLE 281
+GS G+KG+ G+P G P E
Sbjct: 1502 PPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1541
Score = 53.5 bits (127), Expect = 3e-07
Identities = 80/345 (23%), Positives = 119/345 (34%), Gaps = 77/345 (22%)
Query: 53 DQMGSVEKLTTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPL 112
+++ + E LT + S + S + IDG G+ GE + +P
Sbjct: 335 EEIFTEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKP- 393
Query: 113 ERRASVASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRA 172
+ P E+ GVP ++ G+ G+KGE
Sbjct: 394 -----TSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGE-----------------P 431
Query: 173 SVASPGQKGECGVPWREG--GVWRPLERRGSVASPGEKGECGVPWREG------------ 218
+V PG E G P G G+ P +G PG+ G+ G P R G
Sbjct: 432 AVVEPGMLVE-GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPG 490
Query: 219 -----------------------RVWRPLERRASVASPGQKGECGVPWREGPVWRPLERR 255
+ + ++A +A G G G+ R GPV
Sbjct: 491 TMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPV------- 543
Query: 256 GSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASVA 315
G S G KGE G P +G P + G+ G+ G P +GG P E A
Sbjct: 544 GGPGSSGAKGESGDPGPQG----PRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAK-- 597
Query: 316 SPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREGRV 360
G++G G+P G RG PG G+ G+R +G +
Sbjct: 598 --GDRGFDGLPGLPGDKGH-RGERGPQGPPGPPGDDGMRGEDGEI 639
>gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [Homo
sapiens]
Length = 828
Score = 94.0 bits (232), Expect = 2e-19
Identities = 95/301 (31%), Positives = 118/301 (39%), Gaps = 33/301 (10%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
P R + G G G+KG G P EG + P + PG KGE G
Sbjct: 257 PSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGV----PGFKGEKGEF 312
Query: 131 WREGRVWRP--LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWR 188
+GR P + G+ G+ G G P +G R PG+ G G
Sbjct: 313 GADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGN----RGPDGYPGEAGSPGERGD 368
Query: 189 EGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPV 248
+GG P R G PGE G G +G P SPG KG G P GP
Sbjct: 369 QGGKGDP-GRPGRRGPPGEIGAKGSKGYQGNSGAP-------GSPGVKGAKGGPGPRGPK 420
Query: 249 WRPLER-----RGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEG- 302
P R +GS S G KGE G P EG P V + G KG+ G+P G
Sbjct: 421 GEPGRRGDPGTKGSPGSDGPKGEKGDPGPEG----PRGLAGEVGNKGAKGDRGLPGPRGP 476
Query: 303 -GVWRPLERRASVASPGE---KGECGVPWREGGVWRP-LDRRGSVASPGEKGECGVRWRE 357
G ++ S PG+ +G+ G P +G RP G +PGEKGE G R E
Sbjct: 477 QGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPE 536
Query: 358 G 358
G
Sbjct: 537 G 537
Score = 90.9 bits (224), Expect = 2e-18
Identities = 97/300 (32%), Positives = 118/300 (39%), Gaps = 28/300 (9%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIP---WTEGQVWRPLERRASVASPGEKGEC 127
P P P+ + GE G A G KG G+ T+GQ + L R G+ G
Sbjct: 293 PIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGK-LGRIGPPGCKGDPGNR 351
Query: 128 GVPWREGRVWRPLDR--RGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGEC 183
G G P +R +G PG G G P G G + SPG KG
Sbjct: 352 GPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAK 411
Query: 184 GVPWREGGVWRPLER-----RGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGE 238
G P G P R +GS S G KGE G P EG P V + G KG+
Sbjct: 412 GGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEG----PRGLAGEVGNKGAKGD 467
Query: 239 CGVPWREGPVWRPLE--RRGSVASPGE---KGECGVPWTEGGVWRP-LERRASVASPGEK 292
G+P GP E ++GS PG+ +G+ G P +G RP +PGEK
Sbjct: 468 RGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEK 527
Query: 293 GECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECG 352
GE G EGG PG KGE G P G P RG PG +GE G
Sbjct: 528 GEPGPRGPEGG----RGDFGLKGEPGRKGEKGEPADPGPPGEP-GPRGPRGVPGPEGEPG 582
Score = 58.9 bits (141), Expect = 7e-09
Identities = 49/147 (33%), Positives = 63/147 (42%), Gaps = 8/147 (5%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLER--RASVASPGEKGECGVPWR 132
P P R + GE G+ A G++G G +G + P ++ R G +G+ G P
Sbjct: 447 PGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGP 506
Query: 133 EGRVWRP-LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGG 191
+G RP G +PGEKGE G EGG PG+KGE G P G
Sbjct: 507 KGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGG----RGDFGLKGEPGRKGEKGEPADPGP 562
Query: 192 VWRPLERRGSVASPGEKGECGVPWREG 218
P RG PG +GE G P G
Sbjct: 563 PGEP-GPRGPRGVPGPEGEPGPPGDPG 588
Score = 48.1 bits (113), Expect = 1e-05
Identities = 47/154 (30%), Positives = 62/154 (40%), Gaps = 35/154 (22%)
Query: 206 GEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKG 265
G KG G +G + P E PGQKG G P EGP+ P +G GEKG
Sbjct: 259 GPKGYRGQKGAKGNMGEPGE-------PGQKGRQGDPGIEGPIGFP-GPKGVPGFKGEKG 310
Query: 266 ECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGV 325
E G +G +PG G+ G +G + R + PG KG+ G
Sbjct: 311 EFGADGRKG-------------APGLAGKNGTDGQKGKLGR-------IGPPGCKGDPGN 350
Query: 326 PWREGGVWRPLDRRGSVASPGEKGECGVRWREGR 359
+G G SPGE+G+ G + GR
Sbjct: 351 RGPDG-------YPGEAGSPGERGDQGGKGDPGR 377
>gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Homo
sapiens]
Length = 918
Score = 94.0 bits (232), Expect = 2e-19
Identities = 95/301 (31%), Positives = 118/301 (39%), Gaps = 33/301 (10%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
P R + G G G+KG G P EG + P + PG KGE G
Sbjct: 257 PSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGV----PGFKGEKGEF 312
Query: 131 WREGRVWRP--LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWR 188
+GR P + G+ G+ G G P +G R PG+ G G
Sbjct: 313 GADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGN----RGPDGYPGEAGSPGERGD 368
Query: 189 EGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPV 248
+GG P R G PGE G G +G P SPG KG G P GP
Sbjct: 369 QGGKGDP-GRPGRRGPPGEIGAKGSKGYQGNSGAP-------GSPGVKGAKGGPGPRGPK 420
Query: 249 WRPLER-----RGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEG- 302
P R +GS S G KGE G P EG P V + G KG+ G+P G
Sbjct: 421 GEPGRRGDPGTKGSPGSDGPKGEKGDPGPEG----PRGLAGEVGNKGAKGDRGLPGPRGP 476
Query: 303 -GVWRPLERRASVASPGE---KGECGVPWREGGVWRP-LDRRGSVASPGEKGECGVRWRE 357
G ++ S PG+ +G+ G P +G RP G +PGEKGE G R E
Sbjct: 477 QGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPE 536
Query: 358 G 358
G
Sbjct: 537 G 537
Score = 90.9 bits (224), Expect = 2e-18
Identities = 97/300 (32%), Positives = 118/300 (39%), Gaps = 28/300 (9%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIP---WTEGQVWRPLERRASVASPGEKGEC 127
P P P+ + GE G A G KG G+ T+GQ + L R G+ G
Sbjct: 293 PIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGK-LGRIGPPGCKGDPGNR 351
Query: 128 GVPWREGRVWRPLDR--RGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGEC 183
G G P +R +G PG G G P G G + SPG KG
Sbjct: 352 GPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAK 411
Query: 184 GVPWREGGVWRPLER-----RGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGE 238
G P G P R +GS S G KGE G P EG P V + G KG+
Sbjct: 412 GGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEG----PRGLAGEVGNKGAKGD 467
Query: 239 CGVPWREGPVWRPLE--RRGSVASPGE---KGECGVPWTEGGVWRP-LERRASVASPGEK 292
G+P GP E ++GS PG+ +G+ G P +G RP +PGEK
Sbjct: 468 RGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEK 527
Query: 293 GECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECG 352
GE G EGG PG KGE G P G P RG PG +GE G
Sbjct: 528 GEPGPRGPEGG----RGDFGLKGEPGRKGEKGEPADPGPPGEP-GPRGPRGVPGPEGEPG 582
Score = 58.9 bits (141), Expect = 7e-09
Identities = 49/147 (33%), Positives = 63/147 (42%), Gaps = 8/147 (5%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLER--RASVASPGEKGECGVPWR 132
P P R + GE G+ A G++G G +G + P ++ R G +G+ G P
Sbjct: 447 PGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGP 506
Query: 133 EGRVWRP-LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGG 191
+G RP G +PGEKGE G EGG PG+KGE G P G
Sbjct: 507 KGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGG----RGDFGLKGEPGRKGEKGEPADPGP 562
Query: 192 VWRPLERRGSVASPGEKGECGVPWREG 218
P RG PG +GE G P G
Sbjct: 563 PGEP-GPRGPRGVPGPEGEPGPPGDPG 588
Score = 48.1 bits (113), Expect = 1e-05
Identities = 47/154 (30%), Positives = 62/154 (40%), Gaps = 35/154 (22%)
Query: 206 GEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKG 265
G KG G +G + P E PGQKG G P EGP+ P +G GEKG
Sbjct: 259 GPKGYRGQKGAKGNMGEPGE-------PGQKGRQGDPGIEGPIGFP-GPKGVPGFKGEKG 310
Query: 266 ECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGV 325
E G +G +PG G+ G +G + R + PG KG+ G
Sbjct: 311 EFGADGRKG-------------APGLAGKNGTDGQKGKLGR-------IGPPGCKGDPGN 350
Query: 326 PWREGGVWRPLDRRGSVASPGEKGECGVRWREGR 359
+G G SPGE+G+ G + GR
Sbjct: 351 RGPDG-------YPGEAGSPGERGDQGGKGDPGR 377
>gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Homo
sapiens]
Length = 1019
Score = 94.0 bits (232), Expect = 2e-19
Identities = 95/301 (31%), Positives = 118/301 (39%), Gaps = 33/301 (10%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
P R + G G G+KG G P EG + P + PG KGE G
Sbjct: 257 PSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGV----PGFKGEKGEF 312
Query: 131 WREGRVWRP--LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWR 188
+GR P + G+ G+ G G P +G R PG+ G G
Sbjct: 313 GADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGN----RGPDGYPGEAGSPGERGD 368
Query: 189 EGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPV 248
+GG P R G PGE G G +G P SPG KG G P GP
Sbjct: 369 QGGKGDP-GRPGRRGPPGEIGAKGSKGYQGNSGAP-------GSPGVKGAKGGPGPRGPK 420
Query: 249 WRPLER-----RGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEG- 302
P R +GS S G KGE G P EG P V + G KG+ G+P G
Sbjct: 421 GEPGRRGDPGTKGSPGSDGPKGEKGDPGPEG----PRGLAGEVGNKGAKGDRGLPGPRGP 476
Query: 303 -GVWRPLERRASVASPGE---KGECGVPWREGGVWRP-LDRRGSVASPGEKGECGVRWRE 357
G ++ S PG+ +G+ G P +G RP G +PGEKGE G R E
Sbjct: 477 QGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPE 536
Query: 358 G 358
G
Sbjct: 537 G 537
Score = 90.9 bits (224), Expect = 2e-18
Identities = 97/300 (32%), Positives = 118/300 (39%), Gaps = 28/300 (9%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIP---WTEGQVWRPLERRASVASPGEKGEC 127
P P P+ + GE G A G KG G+ T+GQ + L R G+ G
Sbjct: 293 PIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGK-LGRIGPPGCKGDPGNR 351
Query: 128 GVPWREGRVWRPLDR--RGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGEC 183
G G P +R +G PG G G P G G + SPG KG
Sbjct: 352 GPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAK 411
Query: 184 GVPWREGGVWRPLER-----RGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGE 238
G P G P R +GS S G KGE G P EG P V + G KG+
Sbjct: 412 GGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEG----PRGLAGEVGNKGAKGD 467
Query: 239 CGVPWREGPVWRPLE--RRGSVASPGE---KGECGVPWTEGGVWRP-LERRASVASPGEK 292
G+P GP E ++GS PG+ +G+ G P +G RP +PGEK
Sbjct: 468 RGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEK 527
Query: 293 GECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECG 352
GE G EGG PG KGE G P G P RG PG +GE G
Sbjct: 528 GEPGPRGPEGG----RGDFGLKGEPGRKGEKGEPADPGPPGEP-GPRGPRGVPGPEGEPG 582
Score = 58.9 bits (141), Expect = 7e-09
Identities = 49/147 (33%), Positives = 63/147 (42%), Gaps = 8/147 (5%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLER--RASVASPGEKGECGVPWR 132
P P R + GE G+ A G++G G +G + P ++ R G +G+ G P
Sbjct: 447 PGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGP 506
Query: 133 EGRVWRP-LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGG 191
+G RP G +PGEKGE G EGG PG+KGE G P G
Sbjct: 507 KGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGG----RGDFGLKGEPGRKGEKGEPADPGP 562
Query: 192 VWRPLERRGSVASPGEKGECGVPWREG 218
P RG PG +GE G P G
Sbjct: 563 PGEP-GPRGPRGVPGPEGEPGPPGDPG 588
Score = 48.1 bits (113), Expect = 1e-05
Identities = 47/154 (30%), Positives = 62/154 (40%), Gaps = 35/154 (22%)
Query: 206 GEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKG 265
G KG G +G + P E PGQKG G P EGP+ P +G GEKG
Sbjct: 259 GPKGYRGQKGAKGNMGEPGE-------PGQKGRQGDPGIEGPIGFP-GPKGVPGFKGEKG 310
Query: 266 ECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGV 325
E G +G +PG G+ G +G + R + PG KG+ G
Sbjct: 311 EFGADGRKG-------------APGLAGKNGTDGQKGKLGR-------IGPPGCKGDPGN 350
Query: 326 PWREGGVWRPLDRRGSVASPGEKGECGVRWREGR 359
+G G SPGE+G+ G + GR
Sbjct: 351 RGPDG-------YPGEAGSPGERGDQGGKGDPGR 377
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 92.8 bits (229), Expect = 5e-19
Identities = 99/332 (29%), Positives = 129/332 (38%), Gaps = 46/332 (13%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
PG V PR R GE G A G +G G+P T G P PG +G G+
Sbjct: 692 PGLV-GPRGERGFPGERGSPGAQGLQGPRGLPGTPG-TDGPKGASGPAGPPGAQGPPGLQ 749
Query: 131 WREGR-----VWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGEC 183
G + P RG V GEKG G P ++G G+ P+ + G+KGE
Sbjct: 750 GMPGERGAAGIAGPKGDRGDV---GEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEV 806
Query: 184 GVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPW 243
G P G G+ +PGE+GE G P G P + PG KGE G
Sbjct: 807 GPPGPAGSA-------GARGAPGERGETGPPGPAGFAGPP----GADGQPGAKGEQGEAG 855
Query: 244 REGPVWRPLERRGSVASPGEKGECGVPWTEG--GVWRPLERRASVASPGEKGECGVPWTE 301
++G P +G +PG +G GV +G G P + PG G G P +
Sbjct: 856 QKGDAGAP-GPQGPSGAPGPQGPTGVTGPKGARGAQGP---PGATGFPGAAGRVGPPGSN 911
Query: 302 G--GVWRPLERRASVASPGEKGECGVPWREG--GVWRPLDRRGSVASPGEKGECGVRWRE 357
G G P G +G+ G P R G G+ P G PG+ G G
Sbjct: 912 GNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPP 971
Query: 358 GRVWYSLDKRGSVPAALASQRHALLALPQPQG 389
G P LA QR ++ LP +G
Sbjct: 972 G------------PQGLAGQR-GIVGLPGQRG 990
Score = 91.7 bits (226), Expect = 1e-18
Identities = 99/332 (29%), Positives = 119/332 (35%), Gaps = 32/332 (9%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
P L + G G+ G KGE G P +G+ P E SPG G G+P G
Sbjct: 278 PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN----GSPGPMGPRGLPGERG 333
Query: 135 RVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG--GV 192
R P G+ + G+ G G P G P +PG KGE G G G
Sbjct: 334 RT-GPAGAAGARGNDGQPGPAGPPGPVGPAGGP----GFPGAPGAKGEAGPTGARGPEGA 388
Query: 193 WRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGP----- 247
P G+ SPG G G P +G + S +PG G G P GP
Sbjct: 389 QGPRGEPGTPGSPGPAGASGNPGTDGIP----GAKGSAGAPGIAGAPGFPGPRGPPGPQG 444
Query: 248 VWRPLERRGSVASP---GEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGV 304
PL +G P G KGE G P E G P G++G G P G +
Sbjct: 445 ATGPLGPKGQTGEPGIAGFKGEQG-PKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPI 503
Query: 305 WRPLER-----RASVASPGEKGECGVPWREG--GVWRPLDRRGSVASPGEKGECGVRWRE 357
P ER R G G G P G G+ P G PGE G G R
Sbjct: 504 GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLT 563
Query: 358 GRVWYSLDKRGSVPAALASQRHALLALPQPQG 389
GR +G V + A P PQG
Sbjct: 564 GRPG-DAGPQGKVGPSGAPGEDGRPGPPGPQG 594
Score = 88.6 bits (218), Expect = 9e-18
Identities = 91/300 (30%), Positives = 109/300 (36%), Gaps = 50/300 (16%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
P P P DGEAG AGE+G G G P PG KG G P
Sbjct: 241 PRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTP-------GLPGVKGHRGYP 293
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
+G +G +PG KGE G P G SPG G G+P E
Sbjct: 294 GLDG-------AKGEAGAPGVKGESGSPGENG-------------SPGPMGPRGLP-GER 332
Query: 191 GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGP--V 248
G P G+ + G+ G G P G P +PG KGE G GP
Sbjct: 333 GRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGP----GFPGAPGAKGEAGPTGARGPEGA 388
Query: 249 WRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEG-----G 303
P G+ SPG G G P T+G + S +PG G G P G G
Sbjct: 389 QGPRGEPGTPGSPGPAGASGNPGTDG----IPGAKGSAGAPGIAGAPGFPGPRGPPGPQG 444
Query: 304 VWRPLERRASVASP---GEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREGRV 360
PL + P G KGE G G P +G+ GE+G+ G R G V
Sbjct: 445 ATGPLGPKGQTGEPGIAGFKGEQGPKGEPG----PAGPQGAPGPAGEEGKRGARGEPGGV 500
Score = 88.2 bits (217), Expect = 1e-17
Identities = 95/326 (29%), Positives = 119/326 (36%), Gaps = 68/326 (20%)
Query: 71 PGSVPAP--RPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECG 128
PG AP R DG AG A GE+G G+ +G + PG GE G
Sbjct: 506 PGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKG----------ANGDPGRPGEPG 555
Query: 129 VPWREGRVWRPLD-----RRGSVASPGEKGECGVPWREG-----GVWRPLERRASVASPG 178
+P G RP D + G +PGE G G P +G GV + + PG
Sbjct: 556 LPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPG 615
Query: 179 QKGECGVPWREG-----------------GVWRPLERRGSVASPGEKGECGVPWREGRVW 221
+ GE G+P G G P RG +PG G G+P G
Sbjct: 616 KAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPG--- 672
Query: 222 RPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEG------- 274
P G GE G P GP RG PGE+G G +G
Sbjct: 673 -PPGEGGKPGDQGVPGEAGAPGLVGP-------RGERGFPGERGSPGAQGLQGPRGLPGT 724
Query: 275 -GVWRPLERRASVASPGEKGECGVPWTEG-----GVWRPLERRASVASPGEKGECGVPWR 328
G P PG +G G+ G G+ P R V GEKG G P +
Sbjct: 725 PGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV---GEKGPEGAPGK 781
Query: 329 EG--GVWRPLDRRGSVASPGEKGECG 352
+G G+ P+ G + GEKGE G
Sbjct: 782 DGGRGLTGPIGPPGPAGANGEKGEVG 807
Score = 87.8 bits (216), Expect = 2e-17
Identities = 86/295 (29%), Positives = 109/295 (36%), Gaps = 35/295 (11%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
P P P+ + G G A G G G P G+V P S +PG G G
Sbjct: 868 PSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP----GSNGNPGPPGPPGPS 923
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
++G P RG PG GE G+ + PG+KGE G G
Sbjct: 924 GKDG----PKGARGDSGPPGRAGEPGL-------------QGPAGPPGEKGEPGDDGPSG 966
Query: 191 GVWRP-----LERRGSVASPGEKGECGVPWREGRVWRPLERRASVAS--PGQKGECGVPW 243
P +RG V PG++GE G P G P ++ A AS G G G P
Sbjct: 967 AEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPG 1026
Query: 244 REGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGG 303
GP P R GS + G G G GV +V +PG G G P G
Sbjct: 1027 LTGPAGEP-GREGSPGADGPPGRDGA----AGVKGDRGETGAVGAPGAPGPPGSPGPAGP 1081
Query: 304 VWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
+ + R + G G G P G+ P RG GE GE G++ G
Sbjct: 1082 TGKQGD-RGEAGAQGPMGPSG-PAGARGIQGPQGPRGDKGEAGEPGERGLKGHRG 1134
Score = 84.3 bits (207), Expect = 2e-16
Identities = 82/281 (29%), Positives = 109/281 (38%), Gaps = 48/281 (17%)
Query: 81 RSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPL 140
+ + GEAG G +GE G P G + G +G G P +G P
Sbjct: 683 QGVPGEAGAPGLVGPRGERGFPGERGS-------PGAQGLQGPRGLPGTPGTDG----PK 731
Query: 141 DRRGSVASPGEKGECGVPWREG-----GVWRPLERRASVASPGQKGECGVPWREG--GVW 193
G PG +G G+ G G+ P R V G+KG G P ++G G+
Sbjct: 732 GASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV---GEKGPEGAPGKDGGRGLT 788
Query: 194 RPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLE 253
P+ G + GEKGE G P P + +PG++GE G P G P
Sbjct: 789 GPIGPPGPAGANGEKGEVGPP-------GPAGSAGARGAPGERGETGPPGPAGFAGPP-- 839
Query: 254 RRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEG--GVWRPLERR 311
G+ PG KGE G E G ++ +PG +G G P +G GV P R
Sbjct: 840 --GADGQPGAKGEQG----EAG------QKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 887
Query: 312 ASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECG 352
+ PG G G R G P G+ PG G G
Sbjct: 888 GAQGPPGATGFPGAAGRVG----PPGSNGNPGPPGPPGPSG 924
Score = 83.2 bits (204), Expect = 4e-16
Identities = 90/326 (27%), Positives = 120/326 (36%), Gaps = 66/326 (20%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWR--------PLERRASVASPGEKGE 126
P P+ G+AG G G G+P +G+ P R +PG G
Sbjct: 605 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 664
Query: 127 CGV---PWREGRVWRPLDR--------------RGSVASPGEKGECGVPWREG------- 162
G+ P G +P D+ RG PGE+G G +G
Sbjct: 665 QGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGT 724
Query: 163 -GVWRPLERRASVASPGQKGECGVPWREG-----GVWRPLERRGSVASPGEKGECGVPWR 216
G P PG +G G+ G G+ P RG V GEKG G P +
Sbjct: 725 PGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV---GEKGPEGAPGK 781
Query: 217 EG--RVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEG 274
+G + P+ + G+KGE G P P G+ +PGE+GE G P G
Sbjct: 782 DGGRGLTGPIGPPGPAGANGEKGEVGPP-------GPAGSAGARGAPGERGETGPPGPAG 834
Query: 275 GVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREG--GV 332
P + PG KGE G E G ++ +PG +G G P +G GV
Sbjct: 835 FAGPP----GADGQPGAKGEQG----EAG------QKGDAGAPGPQGPSGAPGPQGPTGV 880
Query: 333 WRPLDRRGSVASPGEKGECGVRWREG 358
P RG+ PG G G R G
Sbjct: 881 TGPKGARGAQGPPGATGFPGAAGRVG 906
Score = 75.9 bits (185), Expect = 6e-14
Identities = 99/365 (27%), Positives = 116/365 (31%), Gaps = 94/365 (25%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRP------------------- 111
P PR R GE G G GE G P G P
Sbjct: 127 PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGG 186
Query: 112 LERRASVA-------------------------------SPGEKGECGVPWREGRVWRPL 140
+ +A A +PGE GE GV G P
Sbjct: 187 FDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMG----PR 242
Query: 141 DRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASP---------------GQKGEC 183
G PG+ GE G P + G G P R +P G KGE
Sbjct: 243 GPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEA 302
Query: 184 GVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPW 243
G P +G P G SPG G G+P GR P + + GQ G G P
Sbjct: 303 GAPGVKGESGSP----GENGSPGPMGPRGLPGERGRT-GPAGAAGARGNDGQPGPAGPPG 357
Query: 244 REGPVWRPLERRGSVASPGEKGECGVPWTEG--GVWRPLERRASVASPGEKGECGVPWTE 301
GP P G +PG KGE G G G P + SPG G G P T+
Sbjct: 358 PVGPAGGP----GFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTD 413
Query: 302 GGVWRPLERRASVASPGEKGECGVPWREG-----GVWRPLDRRGSVASP---GEKGECGV 353
G + S +PG G G P G G PL +G P G KGE G
Sbjct: 414 G----IPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGP 469
Query: 354 RWREG 358
+ G
Sbjct: 470 KGEPG 474
Score = 52.8 bits (125), Expect = 5e-07
Identities = 72/288 (25%), Positives = 97/288 (33%), Gaps = 50/288 (17%)
Query: 95 EKGEC---GIPWTEGQVWRPLERRASVASPG----------EKGEC---GVPWREGRVWR 138
E G C G + + VW+P R V G + +C +P+ E
Sbjct: 30 EAGSCVQDGQRYNDKDVWKPEPCRICVCDTGTVLCDDIICEDVKDCLSPEIPFGECCPIC 89
Query: 139 PLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLER 198
P D + PG KG+ G P + P PG +G G
Sbjct: 90 PTDLATASGQPGPKGQKGEPGDIKDIVGPK------GPPGPQGPAG-------------E 130
Query: 199 RGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWR----PLER 254
+G G+KGE G P GR P +PG G G P GP +
Sbjct: 131 QGPRGDRGDKGEKGAPGPRGRDGEP-------GTPGNPGPPGPPGPPGPPGLGGNFAAQM 183
Query: 255 RGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEG--GVWRPLERRA 312
G + GV G P +PG +G G P G GV P+ R
Sbjct: 184 AGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRG 243
Query: 313 SVASPGEKGECGVPWREG--GVWRPLDRRGSVASPGEKGECGVRWREG 358
PG+ G+ G + G G P +G+ PG G GV+ G
Sbjct: 244 PPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRG 291
Score = 29.3 bits (64), Expect = 6.3
Identities = 32/117 (27%), Positives = 41/117 (35%), Gaps = 18/117 (15%)
Query: 74 VPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWRE 133
+ P+ R GEAG G KG G +G P G++G G
Sbjct: 1108 IQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPP-------GPSGDQGASGPAGPS 1160
Query: 134 GRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
G P G V G+ G G+P G + P R S G+ G G P G
Sbjct: 1161 G----PRGPPGPVGPSGKDGANGIP---GPIGPPGPRGRS----GETGPAGPPGNPG 1206
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 92.8 bits (229), Expect = 5e-19
Identities = 99/332 (29%), Positives = 129/332 (38%), Gaps = 46/332 (13%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
PG V PR R GE G A G +G G+P T G P PG +G G+
Sbjct: 623 PGLV-GPRGERGFPGERGSPGAQGLQGPRGLPGTPG-TDGPKGASGPAGPPGAQGPPGLQ 680
Query: 131 WREGR-----VWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGEC 183
G + P RG V GEKG G P ++G G+ P+ + G+KGE
Sbjct: 681 GMPGERGAAGIAGPKGDRGDV---GEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEV 737
Query: 184 GVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPW 243
G P G G+ +PGE+GE G P G P + PG KGE G
Sbjct: 738 GPPGPAGSA-------GARGAPGERGETGPPGPAGFAGPP----GADGQPGAKGEQGEAG 786
Query: 244 REGPVWRPLERRGSVASPGEKGECGVPWTEG--GVWRPLERRASVASPGEKGECGVPWTE 301
++G P +G +PG +G GV +G G P + PG G G P +
Sbjct: 787 QKGDAGAP-GPQGPSGAPGPQGPTGVTGPKGARGAQGP---PGATGFPGAAGRVGPPGSN 842
Query: 302 G--GVWRPLERRASVASPGEKGECGVPWREG--GVWRPLDRRGSVASPGEKGECGVRWRE 357
G G P G +G+ G P R G G+ P G PG+ G G
Sbjct: 843 GNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPP 902
Query: 358 GRVWYSLDKRGSVPAALASQRHALLALPQPQG 389
G P LA QR ++ LP +G
Sbjct: 903 G------------PQGLAGQR-GIVGLPGQRG 921
Score = 91.7 bits (226), Expect = 1e-18
Identities = 99/332 (29%), Positives = 119/332 (35%), Gaps = 32/332 (9%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
P L + G G+ G KGE G P +G+ P E SPG G G+P G
Sbjct: 209 PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN----GSPGPMGPRGLPGERG 264
Query: 135 RVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG--GV 192
R P G+ + G+ G G P G P +PG KGE G G G
Sbjct: 265 RT-GPAGAAGARGNDGQPGPAGPPGPVGPAGGP----GFPGAPGAKGEAGPTGARGPEGA 319
Query: 193 WRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGP----- 247
P G+ SPG G G P +G + S +PG G G P GP
Sbjct: 320 QGPRGEPGTPGSPGPAGASGNPGTDGIP----GAKGSAGAPGIAGAPGFPGPRGPPGPQG 375
Query: 248 VWRPLERRGSVASP---GEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGV 304
PL +G P G KGE G P E G P G++G G P G +
Sbjct: 376 ATGPLGPKGQTGEPGIAGFKGEQG-PKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPI 434
Query: 305 WRPLER-----RASVASPGEKGECGVPWREG--GVWRPLDRRGSVASPGEKGECGVRWRE 357
P ER R G G G P G G+ P G PGE G G R
Sbjct: 435 GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLT 494
Query: 358 GRVWYSLDKRGSVPAALASQRHALLALPQPQG 389
GR +G V + A P PQG
Sbjct: 495 GRPG-DAGPQGKVGPSGAPGEDGRPGPPGPQG 525
Score = 88.6 bits (218), Expect = 9e-18
Identities = 91/300 (30%), Positives = 109/300 (36%), Gaps = 50/300 (16%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
P P P DGEAG AGE+G G G P PG KG G P
Sbjct: 172 PRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTP-------GLPGVKGHRGYP 224
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
+G +G +PG KGE G P G SPG G G+P E
Sbjct: 225 GLDG-------AKGEAGAPGVKGESGSPGENG-------------SPGPMGPRGLP-GER 263
Query: 191 GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGP--V 248
G P G+ + G+ G G P G P +PG KGE G GP
Sbjct: 264 GRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGP----GFPGAPGAKGEAGPTGARGPEGA 319
Query: 249 WRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEG-----G 303
P G+ SPG G G P T+G + S +PG G G P G G
Sbjct: 320 QGPRGEPGTPGSPGPAGASGNPGTDG----IPGAKGSAGAPGIAGAPGFPGPRGPPGPQG 375
Query: 304 VWRPLERRASVASP---GEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREGRV 360
PL + P G KGE G G P +G+ GE+G+ G R G V
Sbjct: 376 ATGPLGPKGQTGEPGIAGFKGEQGPKGEPG----PAGPQGAPGPAGEEGKRGARGEPGGV 431
Score = 88.2 bits (217), Expect = 1e-17
Identities = 95/326 (29%), Positives = 119/326 (36%), Gaps = 68/326 (20%)
Query: 71 PGSVPAP--RPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECG 128
PG AP R DG AG A GE+G G+ +G + PG GE G
Sbjct: 437 PGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKG----------ANGDPGRPGEPG 486
Query: 129 VPWREGRVWRPLD-----RRGSVASPGEKGECGVPWREG-----GVWRPLERRASVASPG 178
+P G RP D + G +PGE G G P +G GV + + PG
Sbjct: 487 LPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPG 546
Query: 179 QKGECGVPWREG-----------------GVWRPLERRGSVASPGEKGECGVPWREGRVW 221
+ GE G+P G G P RG +PG G G+P G
Sbjct: 547 KAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPG--- 603
Query: 222 RPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEG------- 274
P G GE G P GP RG PGE+G G +G
Sbjct: 604 -PPGEGGKPGDQGVPGEAGAPGLVGP-------RGERGFPGERGSPGAQGLQGPRGLPGT 655
Query: 275 -GVWRPLERRASVASPGEKGECGVPWTEG-----GVWRPLERRASVASPGEKGECGVPWR 328
G P PG +G G+ G G+ P R V GEKG G P +
Sbjct: 656 PGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV---GEKGPEGAPGK 712
Query: 329 EG--GVWRPLDRRGSVASPGEKGECG 352
+G G+ P+ G + GEKGE G
Sbjct: 713 DGGRGLTGPIGPPGPAGANGEKGEVG 738
Score = 87.8 bits (216), Expect = 2e-17
Identities = 86/295 (29%), Positives = 109/295 (36%), Gaps = 35/295 (11%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
P P P+ + G G A G G G P G+V P S +PG G G
Sbjct: 799 PSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP----GSNGNPGPPGPPGPS 854
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
++G P RG PG GE G+ + PG+KGE G G
Sbjct: 855 GKDG----PKGARGDSGPPGRAGEPGL-------------QGPAGPPGEKGEPGDDGPSG 897
Query: 191 GVWRP-----LERRGSVASPGEKGECGVPWREGRVWRPLERRASVAS--PGQKGECGVPW 243
P +RG V PG++GE G P G P ++ A AS G G G P
Sbjct: 898 AEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPG 957
Query: 244 REGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGG 303
GP P R GS + G G G GV +V +PG G G P G
Sbjct: 958 LTGPAGEP-GREGSPGADGPPGRDGA----AGVKGDRGETGAVGAPGAPGPPGSPGPAGP 1012
Query: 304 VWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
+ + R + G G G P G+ P RG GE GE G++ G
Sbjct: 1013 TGKQGD-RGEAGAQGPMGPSG-PAGARGIQGPQGPRGDKGEAGEPGERGLKGHRG 1065
Score = 84.3 bits (207), Expect = 2e-16
Identities = 82/281 (29%), Positives = 109/281 (38%), Gaps = 48/281 (17%)
Query: 81 RSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPL 140
+ + GEAG G +GE G P G + G +G G P +G P
Sbjct: 614 QGVPGEAGAPGLVGPRGERGFPGERGS-------PGAQGLQGPRGLPGTPGTDG----PK 662
Query: 141 DRRGSVASPGEKGECGVPWREG-----GVWRPLERRASVASPGQKGECGVPWREG--GVW 193
G PG +G G+ G G+ P R V G+KG G P ++G G+
Sbjct: 663 GASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV---GEKGPEGAPGKDGGRGLT 719
Query: 194 RPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLE 253
P+ G + GEKGE G P P + +PG++GE G P G P
Sbjct: 720 GPIGPPGPAGANGEKGEVGPP-------GPAGSAGARGAPGERGETGPPGPAGFAGPP-- 770
Query: 254 RRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEG--GVWRPLERR 311
G+ PG KGE G E G ++ +PG +G G P +G GV P R
Sbjct: 771 --GADGQPGAKGEQG----EAG------QKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 818
Query: 312 ASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECG 352
+ PG G G R G P G+ PG G G
Sbjct: 819 GAQGPPGATGFPGAAGRVG----PPGSNGNPGPPGPPGPSG 855
Score = 83.2 bits (204), Expect = 4e-16
Identities = 90/326 (27%), Positives = 120/326 (36%), Gaps = 66/326 (20%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWR--------PLERRASVASPGEKGE 126
P P+ G+AG G G G+P +G+ P R +PG G
Sbjct: 536 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 595
Query: 127 CGV---PWREGRVWRPLDR--------------RGSVASPGEKGECGVPWREG------- 162
G+ P G +P D+ RG PGE+G G +G
Sbjct: 596 QGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGT 655
Query: 163 -GVWRPLERRASVASPGQKGECGVPWREG-----GVWRPLERRGSVASPGEKGECGVPWR 216
G P PG +G G+ G G+ P RG V GEKG G P +
Sbjct: 656 PGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV---GEKGPEGAPGK 712
Query: 217 EG--RVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEG 274
+G + P+ + G+KGE G P P G+ +PGE+GE G P G
Sbjct: 713 DGGRGLTGPIGPPGPAGANGEKGEVGPP-------GPAGSAGARGAPGERGETGPPGPAG 765
Query: 275 GVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREG--GV 332
P + PG KGE G E G ++ +PG +G G P +G GV
Sbjct: 766 FAGPP----GADGQPGAKGEQG----EAG------QKGDAGAPGPQGPSGAPGPQGPTGV 811
Query: 333 WRPLDRRGSVASPGEKGECGVRWREG 358
P RG+ PG G G R G
Sbjct: 812 TGPKGARGAQGPPGATGFPGAAGRVG 837
Score = 75.9 bits (185), Expect = 6e-14
Identities = 99/365 (27%), Positives = 116/365 (31%), Gaps = 94/365 (25%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRP------------------- 111
P PR R GE G G GE G P G P
Sbjct: 58 PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGG 117
Query: 112 LERRASVA-------------------------------SPGEKGECGVPWREGRVWRPL 140
+ +A A +PGE GE GV G P
Sbjct: 118 FDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMG----PR 173
Query: 141 DRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASP---------------GQKGEC 183
G PG+ GE G P + G G P R +P G KGE
Sbjct: 174 GPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEA 233
Query: 184 GVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPW 243
G P +G P G SPG G G+P GR P + + GQ G G P
Sbjct: 234 GAPGVKGESGSP----GENGSPGPMGPRGLPGERGRT-GPAGAAGARGNDGQPGPAGPPG 288
Query: 244 REGPVWRPLERRGSVASPGEKGECGVPWTEG--GVWRPLERRASVASPGEKGECGVPWTE 301
GP P G +PG KGE G G G P + SPG G G P T+
Sbjct: 289 PVGPAGGP----GFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTD 344
Query: 302 GGVWRPLERRASVASPGEKGECGVPWREG-----GVWRPLDRRGSVASP---GEKGECGV 353
G + S +PG G G P G G PL +G P G KGE G
Sbjct: 345 G----IPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGP 400
Query: 354 RWREG 358
+ G
Sbjct: 401 KGEPG 405
Score = 55.5 bits (132), Expect = 8e-08
Identities = 69/251 (27%), Positives = 86/251 (34%), Gaps = 51/251 (20%)
Query: 118 VASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASP 177
V PG KG+ G P + P G GE+G G
Sbjct: 28 VRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRG-------------------DR 68
Query: 178 GQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREG-------RVWRPLERRASV 230
G KGE G P G P G+ +PG G G P G ++ + +A
Sbjct: 69 GDKGEKGAPGPRGRDGEP----GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGG 124
Query: 231 AS----PGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASV 286
A G G G GP P +G +PGE GE GV G P
Sbjct: 125 AQLGVMQGPMGPMGPRGPPGPAGAP-GPQGFQGNPGEPGEPGV----SGPMGPRGPPGPP 179
Query: 287 ASPGEKGECGVPWTEGGVWRPLERRA-----SVASPGEKGECGVPWREGGVWRPLDRRGS 341
PG+ GE G P G P + A + PG KG G P +G +G
Sbjct: 180 GKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGA-------KGE 232
Query: 342 VASPGEKGECG 352
+PG KGE G
Sbjct: 233 AGAPGVKGESG 243
Score = 48.9 bits (115), Expect = 8e-06
Identities = 55/195 (28%), Positives = 69/195 (35%), Gaps = 21/195 (10%)
Query: 178 GQKGECGV------PWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVA 231
GQKGE G P G P +G G+KGE G P GR P
Sbjct: 35 GQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP-------G 87
Query: 232 SPGQKGECGVPWREGPVWR----PLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVA 287
+PG G G P GP + G + GV G P
Sbjct: 88 TPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAG 147
Query: 288 SPGEKGECGVPWTEG--GVWRPLERRASVASPGEKGECGVPWREG--GVWRPLDRRGSVA 343
+PG +G G P G GV P+ R PG+ G+ G + G G P +G+
Sbjct: 148 APGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARG 207
Query: 344 SPGEKGECGVRWREG 358
PG G GV+ G
Sbjct: 208 FPGTPGLPGVKGHRG 222
Score = 29.3 bits (64), Expect = 6.3
Identities = 32/117 (27%), Positives = 41/117 (35%), Gaps = 18/117 (15%)
Query: 74 VPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWRE 133
+ P+ R GEAG G KG G +G P G++G G
Sbjct: 1039 IQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPP-------GPSGDQGASGPAGPS 1091
Query: 134 GRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
G P G V G+ G G+P G + P R S G+ G G P G
Sbjct: 1092 G----PRGPPGPVGPSGKDGANGIP---GPIGPPGPRGRS----GETGPAGPPGNPG 1137
>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
Length = 1604
Score = 90.9 bits (224), Expect = 2e-18
Identities = 94/319 (29%), Positives = 123/319 (38%), Gaps = 55/319 (17%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVW-----RPLERRASVASPGEKG 125
PG+ P L I GE G++ +AGEKGE G P +EG P R + GEKG
Sbjct: 1092 PGAT-GPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKG 1150
Query: 126 ECGVPWREGRVW--RPLDRRGSVASPG------EKGECGVPWREGGVWRPLERRASVASP 177
+ G + G P G V SPG EKG G+ G P P
Sbjct: 1151 DQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSP----GPPGPP 1206
Query: 178 GQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKG 237
G +G G+ +G +P RG G G G P +G+ P PG KG
Sbjct: 1207 GIQGPAGLDGLDGKDGKP-GLRGDPGPAGPPGLMGPPGFKGKTGHP-------GLPGPKG 1258
Query: 238 ECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRP-------------LERRA 284
+CG P G RP G+ PG G G P G V P + +
Sbjct: 1259 DCGKPGPPGSTGRP----GAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKG 1314
Query: 285 SVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREG-----GVWRPLDRR 339
+ GE+G G+P G P PGE G G +EG G + P +
Sbjct: 1315 DRGATGERGLAGLPGQPGPPGHP-------GPPGEPGTDGAAGKEGPPGKQGFYGPPGPK 1367
Query: 340 GSVASPGEKGECGVRWREG 358
G + G+KG+ G + R G
Sbjct: 1368 GDPGAAGQKGQAGEKGRAG 1386
Score = 85.5 bits (210), Expect = 7e-17
Identities = 103/356 (28%), Positives = 126/356 (35%), Gaps = 61/356 (17%)
Query: 11 PRVERAECGASAGALTIVSSHGGDSDKDLCARTQIYGAQPREDQMGSVEKLTTSAFLSAK 70
PR E A S G V S G L + G G + F
Sbjct: 1000 PRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGF---- 1055
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
PG+V +P L + GE G + G+KGE G P G PG G G+P
Sbjct: 1056 PGAVGSPG-LPGLQGERGLTGLTGDKGEPGPPGQPGY-------------PGATGPPGLP 1101
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREG-----GVWRPLERRASVASPGQKGECGV 185
+G RG S GEKGE G P EG G P R + G+KG+ G
Sbjct: 1102 GIKG-------ERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGF 1154
Query: 186 PWREG--GVWRPLERRGSVASPG------EKGECGVPWREGRVWRPLERRASVASPGQKG 237
+ G G P G V SPG EKG G+ G P PG +G
Sbjct: 1155 QGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSP----GPPGPPGIQG 1210
Query: 238 ECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGV 297
G+ +G +P RG G G G P +G P PG KG+CG
Sbjct: 1211 PAGLDGLDGKDGKP-GLRGDPGPAGPPGLMGPPGFKGKTGHP-------GLPGPKGDCGK 1262
Query: 298 PWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGV 353
P G RP + GE G G R G P G PG+ G G+
Sbjct: 1263 PGPPGSTGRP-------GAEGEPGAMGPQGRPG----PPGHVGPPGPPGQPGPAGI 1307
Score = 84.0 bits (206), Expect = 2e-16
Identities = 84/326 (25%), Positives = 124/326 (38%), Gaps = 51/326 (15%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRP----- 139
G+ GH G KG+CG P G RP + PG G G P G V P
Sbjct: 1246 GKTGHPGLPGPKGDCGKPGPPGSTGRP----GAEGEPGAMGPQGRPGPPGHVGPPGPPGQ 1301
Query: 140 --------LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGG 191
+ +G + GE+G G+P + G P PG+ G G +EG
Sbjct: 1302 PGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHP-------GPPGEPGTDGAAGKEG- 1353
Query: 192 VWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRP 251
P ++G PG KG+ G ++G+ R PG+ G G GP
Sbjct: 1354 ---PPGKQGFYGPPGPKGDPGAAGQKGQAGEK-GRAGMPGGPGKSGSMGPVGPPGPAGE- 1408
Query: 252 LERRGSVASPGEKGECGVPWTEGGVWRPLE--------RRASVASPGEKGECGVPWTEGG 303
RG +PG G G+P G + + R+ + E+ + +
Sbjct: 1409 ---RGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDER----MAYYTSR 1461
Query: 304 VWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREGRVWYS 363
+ P+E A+ PG G+ G P R G P G + G +G GVR G +
Sbjct: 1462 MQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSP-GLPGQIGREGRQGLPGVRGLPG----T 1516
Query: 364 LDKRGSVPAALASQRHALLALPQPQG 389
++G + +A + + L P PQG
Sbjct: 1517 KGEKGDIGIGIAGE-NGLPGPPGPQG 1541
Score = 70.1 bits (170), Expect = 3e-12
Identities = 80/293 (27%), Positives = 113/293 (38%), Gaps = 45/293 (15%)
Query: 79 PLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWR 138
PL+ +G G +G G G+P + G+ + E+ G+ G GVP + GR R
Sbjct: 369 PLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEK-------GDGGIKGVPGKPGRDGR 421
Query: 139 PLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGV-----PWREGGVW 193
P G + G KG+ G P G P PG G G+ P GG
Sbjct: 422 P----GEICVIGPKGQKGDP----GFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPP 473
Query: 194 RPLERRGSVASPGEKGECGVPWR---EGRVWRPLERRASVASPGQKGECGVPWREGPVWR 250
P +GS PG++G G P + +G P E ++ G + G+P + GP
Sbjct: 474 GPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPE-GFQNFVGLPGKPGPKGE 532
Query: 251 ---PLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRP 307
P+ RG G KGE G P + + V+S G G+ G P
Sbjct: 533 PGDPVPARGDPGIQGIKGEKGEPCLSCS--SVVGAQHLVSSTGASGDVGSP--------- 581
Query: 308 LERRASVASPGEKGECGVPWREG--GVWRPLDRRGSVASPGEKGECGVRWREG 358
PG G GVP +G G + GS PG G G++ +G
Sbjct: 582 -----GFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKG 629
Score = 68.6 bits (166), Expect = 9e-12
Identities = 96/323 (29%), Positives = 109/323 (33%), Gaps = 49/323 (15%)
Query: 67 LSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGE----CGIPWTEGQVWRPLERRASVAS-- 120
L KPG P G+ G GEKGE C + V S
Sbjct: 523 LPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPG 582
Query: 121 ---PGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRAS---- 173
PG G GVP +G G SPG G G +G P E +
Sbjct: 583 FGLPGLPGRAGVPGLKGEKGN-FGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNL 641
Query: 174 -------VASPGQKGECGVPWREG----GVWRPLERRGSVASPGEKGECGVPWREGRVWR 222
VA PG GE G P G G RG G+ G G P G R
Sbjct: 642 QDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGR 701
Query: 223 P-LERRASVASP-GQKGECG-----VPWREGPVWRPLERRGSVASPGEKGECGVPWTEGG 275
P L V P G KGE G P +G V + G PG KGE G G
Sbjct: 702 PGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTV---TDMAGRPGQPGPKGEQG----PEG 754
Query: 276 VWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASVASP-GEKGECGVPWREG---- 330
V RP PG G G P +G P V P GE G G+P +G
Sbjct: 755 VGRP----GKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGP 810
Query: 331 -GVWRPLDRRGSVASPGEKGECG 352
G P +G+ SPG KG G
Sbjct: 811 RGPPGPTGEKGAQGSPGVKGATG 833
Score = 68.6 bits (166), Expect = 9e-12
Identities = 103/363 (28%), Positives = 136/363 (37%), Gaps = 75/363 (20%)
Query: 33 GDSDKDLCARTQIYGAQPREDQMGSVEKLTTSAF-LSAKPG--SVPAPRPLRSIDGEAGH 89
G+ + + + + GAQ G+ + + F L PG VP + + GEAG
Sbjct: 550 GEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGP 609
Query: 90 SEAAGEKGECGIPWTEGQVWRPLE-------------RRASVASP-GEKGE-----CGVP 130
+ + G G G +G P E R ++ P GEKGE G+P
Sbjct: 610 AGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLP 669
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRP-LERRASVASP-GQKGECG---- 184
++G+ RG G+ G G P G RP L V P G KGE G
Sbjct: 670 GKQGKA----GERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCT 725
Query: 185 -VPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPW 243
P +G V + G PG KGE G EG V PG+ G+ G+P
Sbjct: 726 ACPSLQGTV---TDMAGRPGQPGPKGEQGP---EG-----------VGRPGKPGQPGLPG 768
Query: 244 REGPVWRPLERRGSVASPGEKGECGVPWTEG-GVWRPLERRASVASPGEKGECGVPWTEG 302
+GP PG KG G P G GV P + +PG G G+P G
Sbjct: 769 VQGP-------------PGLKGVQGEPGPPGRGVQGP---QGEPGAPGLPGIQGLPGPRG 812
Query: 303 GVWRPLERRASVASPGEKGECGVPWREG-GVWRPLDRRGSV------ASPGEKGECGVRW 355
P + + SPG KG G G V P R G +PGEKG G +
Sbjct: 813 PP-GPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKG 871
Query: 356 REG 358
G
Sbjct: 872 EPG 874
Score = 65.9 bits (159), Expect = 6e-11
Identities = 87/297 (29%), Positives = 107/297 (36%), Gaps = 59/297 (19%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
PG P P+ G+KG GIP EG +P PG KGE G P
Sbjct: 469 PGGPPGPK---------------GDKGSSGIPGKEGPGGKP-------GKPGVKGEKGDP 506
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
E P + V PG+ G G P P+ R G KGE G P
Sbjct: 507 C-EVCPTLPEGFQNFVGLPGKPGPKGEP------GDPVPARGDPGIQGIKGEKGEPCLSC 559
Query: 191 GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWR 250
+ + V+S G G+ G P G L RA V PG KGE G GP
Sbjct: 560 S--SVVGAQHLVSSTGASGDVGSP---GFGLPGLPGRAGV--PGLKGEKGNFGEAGPA-- 610
Query: 251 PLERRGSVASPGEKGECGVPWTEGGVWRPLERRAS--------VASPGEKGECGVPWTEG 302
GS PG G G+ +G P ++ VA PG GE G P G
Sbjct: 611 -----GSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPG 665
Query: 303 -GVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
G+ + G+KG+ G P G G+ PG GE GV+ G
Sbjct: 666 FGLPGKQGKAGERGLKGQKGDAGNPGDPG-------TPGTTGRPGLSGEPGVQGPAG 715
Score = 62.0 bits (149), Expect = 9e-10
Identities = 86/323 (26%), Positives = 112/323 (34%), Gaps = 73/323 (22%)
Query: 70 KPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASP----GEKG 125
+PG+ P ++ + G G GEKG G P +G ASV+ P G++G
Sbjct: 795 EPGAPGLPG-IQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQG 853
Query: 126 ECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWR-----EGGVWRPLERRASVASPGQK 180
+ G+ G +G GE GEC P + G P S PG +
Sbjct: 854 QTGLRGTPGE-------KGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQ 906
Query: 181 GECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQK---- 236
G G+P G PG G GVP G +P + P ++
Sbjct: 907 GPPGIP-------------GPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLK 953
Query: 237 ---GECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEG---------GVWRPLERRA 284
G+C R P G + GEKG+ G+P G + RP A
Sbjct: 954 SICGDCVQGQRAHP--------GYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEA 1005
Query: 285 ----------SVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWR 334
V SPG G G+P G P R SPG G G P G V
Sbjct: 1006 RGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMR----GSPGPPGPIGPPGFPGAVGS 1061
Query: 335 P-----LDRRGSVASPGEKGECG 352
P RG G+KGE G
Sbjct: 1062 PGLPGLQGERGLTGLTGDKGEPG 1084
Score = 55.1 bits (131), Expect = 1e-07
Identities = 64/252 (25%), Positives = 86/252 (34%), Gaps = 56/252 (22%)
Query: 70 KPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGV 129
K G P P + G AG AGEKG G+P G+ V PG GE G
Sbjct: 1357 KQGFYGPPGP-KGDPGAAGQKGQAGEKGRAGMPGGPGK----SGSMGPVGPPGPAGERGH 1411
Query: 130 PWREGRVWRPLDRRGSVASPGEKGEC--------------------GVPWREGGVWRPLE 169
P G P G PG G+ + + + P+E
Sbjct: 1412 PGAPG----PSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPME 1467
Query: 170 RRASVASPGQKGECGVPWREGGVWRP-----LERRGSVASPGEKGECGVPWREGRVWRPL 224
A+ PG G+ G P R G P + R G PG +G G +G +
Sbjct: 1468 MAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDI---- 1523
Query: 225 ERRASVASPGQKGECGVPWREGPVWRP-LERRGSVASPGEKGECGVPWTEGGVWRPLERR 283
G GE G+P GP P + G+ G++G G+P G
Sbjct: 1524 -------GIGIAGENGLPGPPGPQGPPGYGKMGATGPMGQQGIPGIPGPPG--------- 1567
Query: 284 ASVASPGEKGEC 295
+ PG+ G C
Sbjct: 1568 -PMGQPGKAGHC 1578
>gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]
Length = 957
Score = 90.1 bits (222), Expect = 3e-18
Identities = 86/313 (27%), Positives = 125/313 (39%), Gaps = 39/313 (12%)
Query: 46 YGAQPREDQMGSVEKLTTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTE 105
Y QP +D + + + + PG + R L GE G G+KG+ G+P
Sbjct: 468 YPGQPGQDGKPGYQGIAGTPGVPGSPG-IQGARGLPGYKGEPGRD---GDKGDRGLPGFP 523
Query: 106 GQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVW 165
G P + + + G+KG G ++G +G+ PG G G P R G
Sbjct: 524 GLHGMP-GSKGEMGAKGDKGSPGFYGKKG----AKGEKGNAGFPGLPGPAGEPGRHG--- 575
Query: 166 RPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLE 225
+ + SPG KGE G P G+ G +GE G+P G +
Sbjct: 576 ----KDGLMGSPGFKGEAGSP-------------GAPGQDGTRGEPGIPGFPGNRGL-MG 617
Query: 226 RRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEG--GVWRPLERR 283
++ + PGQ+G+ G P G + G +PG KG G P +G G
Sbjct: 618 QKGEIGPPGQQGKKGAPGMPG-LMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEP 676
Query: 284 ASVASPGEKGECGVPWTEG--GVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGS 341
+ SPGE G G+P +G G + GE G G+P ++G G+
Sbjct: 677 GATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQG----IQGHHGA 732
Query: 342 VASPGEKGECGVR 354
GEKGE GVR
Sbjct: 733 KGERGEKGEPGVR 745
Score = 79.7 bits (195), Expect = 4e-15
Identities = 90/341 (26%), Positives = 129/341 (37%), Gaps = 79/341 (23%)
Query: 32 GGDSDKDLCARTQIYGAQPREDQMGSVEKLTTSAFLSAK-----------PGSVPAPRPL 80
G D+ L ++G + +MG+ + F K PG +P P
Sbjct: 512 GDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPG-LPGPAGE 570
Query: 81 RSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPL 140
G+ G + G KGE G P GQ G +GE G+P G
Sbjct: 571 PGRHGKDGLMGSPGFKGEAGSPGAPGQ-------------DGTRGEPGIPGFPG------ 611
Query: 141 DRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRG 200
RG + G+KGE G P ++G ++ + PG G G P + G G
Sbjct: 612 -NRGLM---GQKGEIGPPGQQG-------KKGAPGMPGLMGSNGSPGQPG-------TPG 653
Query: 201 SVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVAS 260
S S GE G G+P G P + SPG+ G G+P +G ++G +
Sbjct: 654 SKGSKGEPGIQGMPGASGLKGEP----GATGSPGEPGYMGLPGIQG-------KKGDKGN 702
Query: 261 PGEKGECGVPWTEGGVWRPLER--RASVASPGEKGECGVPWTEGGVWRPLERRASVASPG 318
GEKG G G P ++ + + GE+GE G P G + G
Sbjct: 703 QGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAI-------------G 749
Query: 319 EKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREGR 359
KGE GV G+ P +G PG +G G+ + GR
Sbjct: 750 SKGESGV----DGLMGPAGPKGQPGDPGPQGPPGLDGKPGR 786
Score = 57.0 bits (136), Expect = 3e-08
Identities = 72/270 (26%), Positives = 93/270 (34%), Gaps = 61/270 (22%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
G GH A GE+GE G P G + G KGE GV G P +G
Sbjct: 725 GIQGHHGAKGERGEKGEPGVRGAI-------------GSKGESGVDGLMG----PAGPKG 767
Query: 145 SVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVW---RPLERRGS 201
PG +G G+ + G + R V + + + V + G + L + GS
Sbjct: 768 QPGDPGPQGPPGLDGKPGREFSEQFIR-QVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGS 826
Query: 202 VASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASP 261
PG G G G PG G GVP G RP RG P
Sbjct: 827 PGIPGPPGPIGPEGPRG-------------LPGLPGRDGVPGLVGVPGRP-GVRGLKGLP 872
Query: 262 GEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKG 321
G GE G PGE+G G P EG ++ G G
Sbjct: 873 GRNGEKG--------------SQGFGYPGEQGPPGPPGPEG--------PPGISKEGPPG 910
Query: 322 ECGVPWREGGVWRPLDRRGSVASPGEKGEC 351
+ G+P ++G +P G PG G C
Sbjct: 911 DPGLPGKDGDHGKP----GIQGQPGPPGIC 936
>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
sapiens]
Length = 1424
Score = 89.4 bits (220), Expect = 5e-18
Identities = 88/297 (29%), Positives = 123/297 (41%), Gaps = 35/297 (11%)
Query: 80 LRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRP 139
L + G+ G G KG+ GIP + PGE G G+P +G + P
Sbjct: 822 LNGLKGQQGRRGKTGPKGDPGIPGLDRS-----------GFPGETGSPGIPGHQGEM-GP 869
Query: 140 LDRRGSVASP---GEKGECGVPWREG--GVWRPLERRASVASPGQKGECGVPWREGGVWR 194
L +RG +P G GE GV G G P + +PGQ+G G+P +G
Sbjct: 870 LGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929
Query: 195 PLER--RGSVASPGEK------GECGVPWREGRVWRPLER--RASVASPGQKGECGVPWR 244
P + +G +PG G+ G P +G P E+ R PG KG G+P
Sbjct: 930 PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989
Query: 245 EGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRP--LERRASVASPGEKGECGVPWTEG 302
GP P GS +PGE G G+P + G + P +R ++ PG G G+P G
Sbjct: 990 AGPP-GPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHG 1048
Query: 303 GVWRPLERRASVAS-PGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
E S + PG G G P G+ + ++G + PG G G EG
Sbjct: 1049 LQGDKGEPGYSEGTRPGPPGPTGDP----GLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101
Score = 84.3 bits (207), Expect = 2e-16
Identities = 88/312 (28%), Positives = 117/312 (37%), Gaps = 44/312 (14%)
Query: 62 TTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASP 121
T ++ PG +P L + G G AAG KG G P G P P
Sbjct: 477 TQCPYIPGPPG-LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFP-------GFP 528
Query: 122 GEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREG--------GVWRPLERRAS 173
G +G+ G+ +G +P G V PG+ G G P R+G GV +
Sbjct: 529 GAQGDPGLKGEKGETLQP---EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGE 585
Query: 174 VASPGQKGECGVPWREGGVWRP----------LERRGSVASPGEKGECGVPWREGRVWRP 223
+A G+KG+ G P G P +G G +G G P G
Sbjct: 586 LALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPR 645
Query: 224 LERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRP-LER 282
E S PG G G P GP +G PG G+CG P G P +
Sbjct: 646 GELSVSTPVPGPPGPPGPPGHPGP-------QGPPGIPGSLGKCGDPGLPGPDGEPGIPG 698
Query: 283 RASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREG--GVWRPLDRRG 340
PG KG+ G P T+G + P + PG G+ G+P +G V P G
Sbjct: 699 IGFPGPPGPKGDQGFPGTKGSLGCP----GKMGEPGLPGKPGLPGAKGEPAVAMP-GGPG 753
Query: 341 SVASPGEKGECG 352
+ PGE+G G
Sbjct: 754 TPGFPGERGNSG 765
Score = 80.1 bits (196), Expect = 3e-15
Identities = 88/293 (30%), Positives = 110/293 (37%), Gaps = 46/293 (15%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
PGS P P +R G G AGEKGE G+ + P R + + G KG+ G P
Sbjct: 1145 PGS-PGPMGIRGDQGRDGIPGPAGEKGETGL------LRAPPGPRGNPGAQGAKGDRGAP 1197
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
G R+G++ G +G G+ G P PGQ G G P G
Sbjct: 1198 GFPGLP----GRKGAMGDAGPRGPTGIEGFPGPPGLP-----GAIIPGQTGNRGPPGSRG 1248
Query: 191 --GVWRPLERRGS--VASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREG 246
G P GS + G+KG G P +G P + PG+ G G P G
Sbjct: 1249 SPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKG----PPGTAGDMGPPGRLGAPGTPGLPG 1304
Query: 247 PVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWR 306
P P G PG KGE G P G S+ PG G G P G
Sbjct: 1305 PRGDP----GFQGFPGVKGEKGNPGFLG----------SIGPPGPIGPKGPPGVRGDP-G 1349
Query: 307 PLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREGR 359
L+ + SPG G G P +G G PG G CG R + G+
Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQG-------EPGPPGPPGNLGPCGPRGKPGK 1395
Score = 78.6 bits (192), Expect = 9e-15
Identities = 94/327 (28%), Positives = 127/327 (38%), Gaps = 67/327 (20%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASV-------------ASP 121
P P+ + G G G+ GE G+P G E ++ +
Sbjct: 705 PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNS 764
Query: 122 GEKGECGVPWREGRVWRPLDR-----RGSVASPGEKGECGVPWR--EGGVWRPLERRASV 174
GE GE G+P G P + RG PG GE G P R EG P +
Sbjct: 765 GEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG----PRGAQGLP 820
Query: 175 ASPGQKGECGVPWREGGVWRP----LERRGSVASPGEKGECGVPWREGRVWRPLERRASV 230
G KG+ G + G P L+R G PGE G G+P +G + PL +R
Sbjct: 821 GLNGLKGQQGRRGKTGPKGDPGIPGLDRSG---FPGETGSPGIPGHQGEM-GPLGQRGYP 876
Query: 231 ASP---GQKGECGV------PWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLE 281
+P G GE GV P GP P G+ +PG++G G+P +G
Sbjct: 877 GNPGILGPPGEDGVIGMMGFPGAIGPPGPP----GNPGTPGQRGSPGIPGVKG------- 925
Query: 282 RRASVASPGEKGECGVPWTE------GGVWRPLERRASVASPGEKGECGVPWREG----- 330
+R + + GE+G+ G P G P + +PGEKG GVP G
Sbjct: 926 QRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP-GLKGFAGNPGEKGNRGVPGMPGLKGLK 984
Query: 331 ---GVWRPLDRRGSVASPGEKGECGVR 354
G P RG + S G GE G+R
Sbjct: 985 GLPGPAGPPGPRGDLGSTGNPGEPGLR 1011
Score = 78.2 bits (191), Expect = 1e-14
Identities = 89/311 (28%), Positives = 120/311 (38%), Gaps = 61/311 (19%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
PG++ P P G+ G++G GIP +GQ R + + GE+G+ G P
Sbjct: 897 PGAIGPPGP-------PGNPGTPGQRGSPGIPGVKGQ-------RGTPGAKGEQGDKGNP 942
Query: 131 WRE------GRVWRPLDRRGSVASPGEKGECGVPWREG-----------GVWRPLERRAS 173
G P +G +PGEKG GVP G G P S
Sbjct: 943 GPSEISHVIGDKGEP-GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS 1001
Query: 174 VASPGQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASP 233
+PG+ G G+P G + P S G++G G P R GR P
Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMP-------GSKGKRGTLGFPGRAGRPGLP----GIHGLQ 1050
Query: 234 GQKGECGV-----PWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVAS 288
G KGE G P GP P G G+KGE G P G + P + S
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDP----GLPGDMGKKGEMGQPGPPGHL-GPAGPEGAPGS 1105
Query: 289 PGEKGECGVPWTEGGV-WRPLERRASVASPGEKGECGVPWREG-----GVWRPLDRRGSV 342
PG G G P G + ++ + + + PG +G G+P G G+ R G
Sbjct: 1106 PGSPGLPGKPGPHGDLGFKGI--KGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIP 1163
Query: 343 ASPGEKGECGV 353
GEKGE G+
Sbjct: 1164 GPAGEKGETGL 1174
Score = 66.6 bits (161), Expect = 4e-11
Identities = 87/312 (27%), Positives = 114/312 (36%), Gaps = 58/312 (18%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
G G S + GE+G G+P T G P + G KG+ G P +E + LD +G
Sbjct: 121 GVPGCSGSKGEQGFPGLPGTLGYPGIP-------GAAGLKGQKGAPAKEEDI--ELDAKG 171
Query: 145 SVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVAS 204
PG G G+P G V PG G G P G P +G +
Sbjct: 172 DPGLPGAPGPQGLPGPPGFP-------GPVGPPGPPGFFGFP----GAMGPRGPKGHMGE 220
Query: 205 P--GEKGECGVPWREGRVWRPLERRASVASP----------GQKGECGVPWREGPVWRPL 252
G KGE GV G P ++ P G KG G P GP P
Sbjct: 221 RVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPG 280
Query: 253 ERRGSV-ASPGEKGECGVPWTEGGVWRPLER--RASVASPGEKGECGVPWTEGGVWRP-- 307
E GS +PG+ G G P +G P + + PG GE G+ +G + P
Sbjct: 281 ESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGF 340
Query: 308 ---------LERRASVASPGEKGECGVPWREG-----------GVWRPLDRRGSVASPGE 347
+ + +PG G G +G G RP RG+ PG
Sbjct: 341 RGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRP-GLRGAPGWPGL 399
Query: 348 KGECGVRWREGR 359
KG G R R G+
Sbjct: 400 KGSKGERGRPGK 411
Score = 65.5 bits (158), Expect = 8e-11
Identities = 84/320 (26%), Positives = 114/320 (35%), Gaps = 47/320 (14%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRP-----LERRASVASP---G 122
P +P P+ + G G + + G +G G+P G P V P G
Sbjct: 68 PEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSG 127
Query: 123 EKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGE 182
KGE G P G + P G + G KG+ G P +E + L+ + PG G
Sbjct: 128 SKGEQGFPGLPGTLGYP----GIPGAAGLKGQKGAPAKEEDI--ELDAKGDPGLPGAPGP 181
Query: 183 CGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVP 242
G+P G G V PG G G P G R + G KGE GV
Sbjct: 182 QGLPGPPG-------FPGPVGPPGPPGFFGFPGAMGP--RGPKGHMGERVIGHKGERGVK 232
Query: 243 WREGP----------VWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRAS-VASPGE 291
GP + P R G+KG G P G P E S +PG+
Sbjct: 233 GLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGD 292
Query: 292 KGECGVPWTEGGVWRPLER--RASVASPGEKGECGVPWREGGVWRP-----------LDR 338
G G P +G P + + PG GE G+ ++G + P
Sbjct: 293 PGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQE 352
Query: 339 RGSVASPGEKGECGVRWREG 358
+G +PG G G R +G
Sbjct: 353 KGDEGTPGPPGPRGARGPQG 372
Score = 65.1 bits (157), Expect = 1e-10
Identities = 83/309 (26%), Positives = 112/309 (36%), Gaps = 51/309 (16%)
Query: 67 LSAKPGSVPAP--------RPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASV 118
L KPG P + R G G G+KG+ G P G P E +
Sbjct: 295 LQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRG----PTEYYDTY 350
Query: 119 ASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPG 178
G++G G P RG+ G G GVP G L R + PG
Sbjct: 351 QEKGDEGTPGPP----------GPRGARGPQGPSGPPGVPGSPGSSRPGL--RGAPGWPG 398
Query: 179 QKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLE---RRASVAS--- 232
KG G R G + G+ SPG G G+P G P + R+
Sbjct: 399 LKGSKGERGRPGK-----DAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGL 453
Query: 233 PGQKGECGVPWREGPVWRP-LERRGSVASPGEKGECGVPWTEGGVWRPLERRAS--VASP 289
PG G G+P +GP P L PG G G+P G P + A+ SP
Sbjct: 454 PGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSP 513
Query: 290 GEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKG 349
G G G+P G PG +G+ G+ +G +P + G PG +G
Sbjct: 514 GSPGNTGLPGFPG-------------FPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRG 560
Query: 350 ECGVRWREG 358
+ G + +G
Sbjct: 561 QPGRKGLDG 569
Score = 61.6 bits (148), Expect = 1e-09
Identities = 84/301 (27%), Positives = 113/301 (37%), Gaps = 41/301 (13%)
Query: 92 AAGEKGECGIPWTEGQVWRPLER--RASVASPGEKGECGVPWREGRVWRPLDRRGSVASP 149
A GEKGE G P G P ++ PG +G G P G + RG P
Sbjct: 44 AKGEKGEKGFPGPPGS---PGQKGFTGPEGLPGPQGPKGFPGLPG-LTGSKGVRGISGLP 99
Query: 150 GEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVASPGEKG 209
G G G+P G P G KGE G P G + P G + G KG
Sbjct: 100 GFSGSPGLPGTPGNT-GPYGLVGVPGCSGSKGEQGFPGLPGTLGYP----GIPGAAGLKG 154
Query: 210 ECGVPWREGRVWRPLERRASV-ASPGQKGECGVPWREGPVWRP-----------LERRGS 257
+ G P +E + + + +PG +G G P GPV P + RG
Sbjct: 155 QKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP 214
Query: 258 VASPGE-----KGECGVPWTEGGVWRPLERRASVASP----------GEKGECGVPWTEG 302
GE KGE GV G P ++ P G+KG G P G
Sbjct: 215 KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274
Query: 303 GVWRPLERRAS-VASPGEKGECGVPWREGGVWRPLDR--RGSVASPGEKGECGVRWREGR 359
P E S +PG+ G G P ++G P +G+ PG GE G++ ++G
Sbjct: 275 PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGD 334
Query: 360 V 360
+
Sbjct: 335 I 335
>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
sapiens]
Length = 1494
Score = 89.4 bits (220), Expect = 5e-18
Identities = 88/297 (29%), Positives = 123/297 (41%), Gaps = 35/297 (11%)
Query: 80 LRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRP 139
L + G+ G G KG+ GIP + PGE G G+P +G + P
Sbjct: 822 LNGLKGQQGRRGKTGPKGDPGIPGLDRS-----------GFPGETGSPGIPGHQGEM-GP 869
Query: 140 LDRRGSVASP---GEKGECGVPWREG--GVWRPLERRASVASPGQKGECGVPWREGGVWR 194
L +RG +P G GE GV G G P + +PGQ+G G+P +G
Sbjct: 870 LGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929
Query: 195 PLER--RGSVASPGEK------GECGVPWREGRVWRPLER--RASVASPGQKGECGVPWR 244
P + +G +PG G+ G P +G P E+ R PG KG G+P
Sbjct: 930 PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989
Query: 245 EGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRP--LERRASVASPGEKGECGVPWTEG 302
GP P GS +PGE G G+P + G + P +R ++ PG G G+P G
Sbjct: 990 AGPP-GPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHG 1048
Query: 303 GVWRPLERRASVAS-PGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
E S + PG G G P G+ + ++G + PG G G EG
Sbjct: 1049 LQGDKGEPGYSEGTRPGPPGPTGDP----GLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101
Score = 84.3 bits (207), Expect = 2e-16
Identities = 88/312 (28%), Positives = 117/312 (37%), Gaps = 44/312 (14%)
Query: 62 TTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASP 121
T ++ PG +P L + G G AAG KG G P G P P
Sbjct: 477 TQCPYIPGPPG-LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFP-------GFP 528
Query: 122 GEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREG--------GVWRPLERRAS 173
G +G+ G+ +G +P G V PG+ G G P R+G GV +
Sbjct: 529 GAQGDPGLKGEKGETLQP---EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGE 585
Query: 174 VASPGQKGECGVPWREGGVWRP----------LERRGSVASPGEKGECGVPWREGRVWRP 223
+A G+KG+ G P G P +G G +G G P G
Sbjct: 586 LALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPR 645
Query: 224 LERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRP-LER 282
E S PG G G P GP +G PG G+CG P G P +
Sbjct: 646 GELSVSTPVPGPPGPPGPPGHPGP-------QGPPGIPGSLGKCGDPGLPGPDGEPGIPG 698
Query: 283 RASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREG--GVWRPLDRRG 340
PG KG+ G P T+G + P + PG G+ G+P +G V P G
Sbjct: 699 IGFPGPPGPKGDQGFPGTKGSLGCP----GKMGEPGLPGKPGLPGAKGEPAVAMP-GGPG 753
Query: 341 SVASPGEKGECG 352
+ PGE+G G
Sbjct: 754 TPGFPGERGNSG 765
Score = 80.1 bits (196), Expect = 3e-15
Identities = 88/293 (30%), Positives = 110/293 (37%), Gaps = 46/293 (15%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
PGS P P +R G G AGEKGE G+ + P R + + G KG+ G P
Sbjct: 1145 PGS-PGPMGIRGDQGRDGIPGPAGEKGETGL------LRAPPGPRGNPGAQGAKGDRGAP 1197
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
G R+G++ G +G G+ G P PGQ G G P G
Sbjct: 1198 GFPGLP----GRKGAMGDAGPRGPTGIEGFPGPPGLP-----GAIIPGQTGNRGPPGSRG 1248
Query: 191 --GVWRPLERRGS--VASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREG 246
G P GS + G+KG G P +G P + PG+ G G P G
Sbjct: 1249 SPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKG----PPGTAGDMGPPGRLGAPGTPGLPG 1304
Query: 247 PVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWR 306
P P G PG KGE G P G S+ PG G G P G
Sbjct: 1305 PRGDP----GFQGFPGVKGEKGNPGFLG----------SIGPPGPIGPKGPPGVRGDP-G 1349
Query: 307 PLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREGR 359
L+ + SPG G G P +G G PG G CG R + G+
Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQG-------EPGPPGPPGNLGPCGPRGKPGK 1395
Score = 78.6 bits (192), Expect = 9e-15
Identities = 94/327 (28%), Positives = 127/327 (38%), Gaps = 67/327 (20%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASV-------------ASP 121
P P+ + G G G+ GE G+P G E ++ +
Sbjct: 705 PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNS 764
Query: 122 GEKGECGVPWREGRVWRPLDR-----RGSVASPGEKGECGVPWR--EGGVWRPLERRASV 174
GE GE G+P G P + RG PG GE G P R EG P +
Sbjct: 765 GEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG----PRGAQGLP 820
Query: 175 ASPGQKGECGVPWREGGVWRP----LERRGSVASPGEKGECGVPWREGRVWRPLERRASV 230
G KG+ G + G P L+R G PGE G G+P +G + PL +R
Sbjct: 821 GLNGLKGQQGRRGKTGPKGDPGIPGLDRSG---FPGETGSPGIPGHQGEM-GPLGQRGYP 876
Query: 231 ASP---GQKGECGV------PWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLE 281
+P G GE GV P GP P G+ +PG++G G+P +G
Sbjct: 877 GNPGILGPPGEDGVIGMMGFPGAIGPPGPP----GNPGTPGQRGSPGIPGVKG------- 925
Query: 282 RRASVASPGEKGECGVPWTE------GGVWRPLERRASVASPGEKGECGVPWREG----- 330
+R + + GE+G+ G P G P + +PGEKG GVP G
Sbjct: 926 QRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP-GLKGFAGNPGEKGNRGVPGMPGLKGLK 984
Query: 331 ---GVWRPLDRRGSVASPGEKGECGVR 354
G P RG + S G GE G+R
Sbjct: 985 GLPGPAGPPGPRGDLGSTGNPGEPGLR 1011
Score = 78.2 bits (191), Expect = 1e-14
Identities = 89/311 (28%), Positives = 120/311 (38%), Gaps = 61/311 (19%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
PG++ P P G+ G++G GIP +GQ R + + GE+G+ G P
Sbjct: 897 PGAIGPPGP-------PGNPGTPGQRGSPGIPGVKGQ-------RGTPGAKGEQGDKGNP 942
Query: 131 WRE------GRVWRPLDRRGSVASPGEKGECGVPWREG-----------GVWRPLERRAS 173
G P +G +PGEKG GVP G G P S
Sbjct: 943 GPSEISHVIGDKGEP-GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS 1001
Query: 174 VASPGQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASP 233
+PG+ G G+P G + P S G++G G P R GR P
Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMP-------GSKGKRGTLGFPGRAGRPGLP----GIHGLQ 1050
Query: 234 GQKGECGV-----PWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVAS 288
G KGE G P GP P G G+KGE G P G + P + S
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDP----GLPGDMGKKGEMGQPGPPGHL-GPAGPEGAPGS 1105
Query: 289 PGEKGECGVPWTEGGV-WRPLERRASVASPGEKGECGVPWREG-----GVWRPLDRRGSV 342
PG G G P G + ++ + + + PG +G G+P G G+ R G
Sbjct: 1106 PGSPGLPGKPGPHGDLGFKGI--KGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIP 1163
Query: 343 ASPGEKGECGV 353
GEKGE G+
Sbjct: 1164 GPAGEKGETGL 1174
Score = 66.6 bits (161), Expect = 4e-11
Identities = 87/312 (27%), Positives = 114/312 (36%), Gaps = 58/312 (18%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
G G S + GE+G G+P T G P + G KG+ G P +E + LD +G
Sbjct: 121 GVPGCSGSKGEQGFPGLPGTLGYPGIP-------GAAGLKGQKGAPAKEEDI--ELDAKG 171
Query: 145 SVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVAS 204
PG G G+P G V PG G G P G P +G +
Sbjct: 172 DPGLPGAPGPQGLPGPPGFP-------GPVGPPGPPGFFGFP----GAMGPRGPKGHMGE 220
Query: 205 P--GEKGECGVPWREGRVWRPLERRASVASP----------GQKGECGVPWREGPVWRPL 252
G KGE GV G P ++ P G KG G P GP P
Sbjct: 221 RVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPG 280
Query: 253 ERRGSV-ASPGEKGECGVPWTEGGVWRPLER--RASVASPGEKGECGVPWTEGGVWRP-- 307
E GS +PG+ G G P +G P + + PG GE G+ +G + P
Sbjct: 281 ESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGF 340
Query: 308 ---------LERRASVASPGEKGECGVPWREG-----------GVWRPLDRRGSVASPGE 347
+ + +PG G G +G G RP RG+ PG
Sbjct: 341 RGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRP-GLRGAPGWPGL 399
Query: 348 KGECGVRWREGR 359
KG G R R G+
Sbjct: 400 KGSKGERGRPGK 411
Score = 65.5 bits (158), Expect = 8e-11
Identities = 84/320 (26%), Positives = 114/320 (35%), Gaps = 47/320 (14%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRP-----LERRASVASP---G 122
P +P P+ + G G + + G +G G+P G P V P G
Sbjct: 68 PEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSG 127
Query: 123 EKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGE 182
KGE G P G + P G + G KG+ G P +E + L+ + PG G
Sbjct: 128 SKGEQGFPGLPGTLGYP----GIPGAAGLKGQKGAPAKEEDI--ELDAKGDPGLPGAPGP 181
Query: 183 CGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVP 242
G+P G G V PG G G P G R + G KGE GV
Sbjct: 182 QGLPGPPG-------FPGPVGPPGPPGFFGFPGAMGP--RGPKGHMGERVIGHKGERGVK 232
Query: 243 WREGP----------VWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRAS-VASPGE 291
GP + P R G+KG G P G P E S +PG+
Sbjct: 233 GLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGD 292
Query: 292 KGECGVPWTEGGVWRPLER--RASVASPGEKGECGVPWREGGVWRP-----------LDR 338
G G P +G P + + PG GE G+ ++G + P
Sbjct: 293 PGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQE 352
Query: 339 RGSVASPGEKGECGVRWREG 358
+G +PG G G R +G
Sbjct: 353 KGDEGTPGPPGPRGARGPQG 372
Score = 65.1 bits (157), Expect = 1e-10
Identities = 83/309 (26%), Positives = 112/309 (36%), Gaps = 51/309 (16%)
Query: 67 LSAKPGSVPAP--------RPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASV 118
L KPG P + R G G G+KG+ G P G P E +
Sbjct: 295 LQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRG----PTEYYDTY 350
Query: 119 ASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPG 178
G++G G P RG+ G G GVP G L R + PG
Sbjct: 351 QEKGDEGTPGPP----------GPRGARGPQGPSGPPGVPGSPGSSRPGL--RGAPGWPG 398
Query: 179 QKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLE---RRASVAS--- 232
KG G R G + G+ SPG G G+P G P + R+
Sbjct: 399 LKGSKGERGRPGK-----DAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGL 453
Query: 233 PGQKGECGVPWREGPVWRP-LERRGSVASPGEKGECGVPWTEGGVWRPLERRAS--VASP 289
PG G G+P +GP P L PG G G+P G P + A+ SP
Sbjct: 454 PGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSP 513
Query: 290 GEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKG 349
G G G+P G PG +G+ G+ +G +P + G PG +G
Sbjct: 514 GSPGNTGLPGFPG-------------FPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRG 560
Query: 350 ECGVRWREG 358
+ G + +G
Sbjct: 561 QPGRKGLDG 569
Score = 61.6 bits (148), Expect = 1e-09
Identities = 84/301 (27%), Positives = 113/301 (37%), Gaps = 41/301 (13%)
Query: 92 AAGEKGECGIPWTEGQVWRPLER--RASVASPGEKGECGVPWREGRVWRPLDRRGSVASP 149
A GEKGE G P G P ++ PG +G G P G + RG P
Sbjct: 44 AKGEKGEKGFPGPPGS---PGQKGFTGPEGLPGPQGPKGFPGLPG-LTGSKGVRGISGLP 99
Query: 150 GEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVASPGEKG 209
G G G+P G P G KGE G P G + P G + G KG
Sbjct: 100 GFSGSPGLPGTPGNT-GPYGLVGVPGCSGSKGEQGFPGLPGTLGYP----GIPGAAGLKG 154
Query: 210 ECGVPWREGRVWRPLERRASV-ASPGQKGECGVPWREGPVWRP-----------LERRGS 257
+ G P +E + + + +PG +G G P GPV P + RG
Sbjct: 155 QKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP 214
Query: 258 VASPGE-----KGECGVPWTEGGVWRPLERRASVASP----------GEKGECGVPWTEG 302
GE KGE GV G P ++ P G+KG G P G
Sbjct: 215 KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274
Query: 303 GVWRPLERRAS-VASPGEKGECGVPWREGGVWRPLDR--RGSVASPGEKGECGVRWREGR 359
P E S +PG+ G G P ++G P +G+ PG GE G++ ++G
Sbjct: 275 PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGD 334
Query: 360 V 360
+
Sbjct: 335 I 335
Score = 52.8 bits (125), Expect = 5e-07
Identities = 54/183 (29%), Positives = 66/183 (36%), Gaps = 22/183 (12%)
Query: 94 GEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKG 153
G+KG G P +G P + PG G G P G P G PG KG
Sbjct: 1268 GDKGSMGHPGPKG----PPGTAGDMGPPGRLGAPGTPGLPG----PRGDPGFQGFPGVKG 1319
Query: 154 ECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG--GVWRPLERRGSVASPGEKGEC 211
E G P G S+ PG G G P G G + + GS PG GE
Sbjct: 1320 EKGNPGFLG----------SIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEP 1369
Query: 212 GVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPW 271
G+ G P G+ G+ G P GP +GS PG G G+P
Sbjct: 1370 GMQGEPGPPGPP-GNLGPCGPRGKPGKDGKPGTPGPAGEK-GNKGSKGEPGPAGSDGLPG 1427
Query: 272 TEG 274
+G
Sbjct: 1428 LKG 1430
Score = 41.2 bits (95), Expect = 0.002
Identities = 45/151 (29%), Positives = 58/151 (38%), Gaps = 21/151 (13%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
PG +P PR G+ G G KGE G P G + P G KG GV
Sbjct: 1300 PG-LPGPR------GDPGFQGFPGVKGEKGNPGFLGSIGPP-------GPIGPKGPPGVR 1345
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRP--LERRASVASPGQKGECGVPWR 188
G + + + GS PG GE G+ G P L PG+ G+ G P
Sbjct: 1346 GDPGTL-KIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGP 1404
Query: 189 EGGVWRPLERRGSVASPGEKGECGVPWREGR 219
G +GS PG G G+P +G+
Sbjct: 1405 AG----EKGNKGSKGEPGPAGSDGLPGLKGK 1431
>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
sapiens]
Length = 1637
Score = 89.4 bits (220), Expect = 5e-18
Identities = 88/297 (29%), Positives = 123/297 (41%), Gaps = 35/297 (11%)
Query: 80 LRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRP 139
L + G+ G G KG+ GIP + PGE G G+P +G + P
Sbjct: 822 LNGLKGQQGRRGKTGPKGDPGIPGLDRS-----------GFPGETGSPGIPGHQGEM-GP 869
Query: 140 LDRRGSVASP---GEKGECGVPWREG--GVWRPLERRASVASPGQKGECGVPWREGGVWR 194
L +RG +P G GE GV G G P + +PGQ+G G+P +G
Sbjct: 870 LGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929
Query: 195 PLER--RGSVASPGEK------GECGVPWREGRVWRPLER--RASVASPGQKGECGVPWR 244
P + +G +PG G+ G P +G P E+ R PG KG G+P
Sbjct: 930 PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989
Query: 245 EGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRP--LERRASVASPGEKGECGVPWTEG 302
GP P GS +PGE G G+P + G + P +R ++ PG G G+P G
Sbjct: 990 AGPP-GPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHG 1048
Query: 303 GVWRPLERRASVAS-PGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
E S + PG G G P G+ + ++G + PG G G EG
Sbjct: 1049 LQGDKGEPGYSEGTRPGPPGPTGDP----GLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101
Score = 84.3 bits (207), Expect = 2e-16
Identities = 88/312 (28%), Positives = 117/312 (37%), Gaps = 44/312 (14%)
Query: 62 TTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASP 121
T ++ PG +P L + G G AAG KG G P G P P
Sbjct: 477 TQCPYIPGPPG-LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFP-------GFP 528
Query: 122 GEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREG--------GVWRPLERRAS 173
G +G+ G+ +G +P G V PG+ G G P R+G GV +
Sbjct: 529 GAQGDPGLKGEKGETLQP---EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGE 585
Query: 174 VASPGQKGECGVPWREGGVWRP----------LERRGSVASPGEKGECGVPWREGRVWRP 223
+A G+KG+ G P G P +G G +G G P G
Sbjct: 586 LALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPR 645
Query: 224 LERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRP-LER 282
E S PG G G P GP +G PG G+CG P G P +
Sbjct: 646 GELSVSTPVPGPPGPPGPPGHPGP-------QGPPGIPGSLGKCGDPGLPGPDGEPGIPG 698
Query: 283 RASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREG--GVWRPLDRRG 340
PG KG+ G P T+G + P + PG G+ G+P +G V P G
Sbjct: 699 IGFPGPPGPKGDQGFPGTKGSLGCP----GKMGEPGLPGKPGLPGAKGEPAVAMP-GGPG 753
Query: 341 SVASPGEKGECG 352
+ PGE+G G
Sbjct: 754 TPGFPGERGNSG 765
Score = 80.1 bits (196), Expect = 3e-15
Identities = 88/293 (30%), Positives = 110/293 (37%), Gaps = 46/293 (15%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
PGS P P +R G G AGEKGE G+ + P R + + G KG+ G P
Sbjct: 1145 PGS-PGPMGIRGDQGRDGIPGPAGEKGETGL------LRAPPGPRGNPGAQGAKGDRGAP 1197
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
G R+G++ G +G G+ G P PGQ G G P G
Sbjct: 1198 GFPGLP----GRKGAMGDAGPRGPTGIEGFPGPPGLP-----GAIIPGQTGNRGPPGSRG 1248
Query: 191 --GVWRPLERRGS--VASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREG 246
G P GS + G+KG G P +G P + PG+ G G P G
Sbjct: 1249 SPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKG----PPGTAGDMGPPGRLGAPGTPGLPG 1304
Query: 247 PVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWR 306
P P G PG KGE G P G S+ PG G G P G
Sbjct: 1305 PRGDP----GFQGFPGVKGEKGNPGFLG----------SIGPPGPIGPKGPPGVRGDP-G 1349
Query: 307 PLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREGR 359
L+ + SPG G G P +G G PG G CG R + G+
Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQG-------EPGPPGPPGNLGPCGPRGKPGK 1395
Score = 78.6 bits (192), Expect = 9e-15
Identities = 94/327 (28%), Positives = 127/327 (38%), Gaps = 67/327 (20%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASV-------------ASP 121
P P+ + G G G+ GE G+P G E ++ +
Sbjct: 705 PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNS 764
Query: 122 GEKGECGVPWREGRVWRPLDR-----RGSVASPGEKGECGVPWR--EGGVWRPLERRASV 174
GE GE G+P G P + RG PG GE G P R EG P +
Sbjct: 765 GEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG----PRGAQGLP 820
Query: 175 ASPGQKGECGVPWREGGVWRP----LERRGSVASPGEKGECGVPWREGRVWRPLERRASV 230
G KG+ G + G P L+R G PGE G G+P +G + PL +R
Sbjct: 821 GLNGLKGQQGRRGKTGPKGDPGIPGLDRSG---FPGETGSPGIPGHQGEM-GPLGQRGYP 876
Query: 231 ASP---GQKGECGV------PWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLE 281
+P G GE GV P GP P G+ +PG++G G+P +G
Sbjct: 877 GNPGILGPPGEDGVIGMMGFPGAIGPPGPP----GNPGTPGQRGSPGIPGVKG------- 925
Query: 282 RRASVASPGEKGECGVPWTE------GGVWRPLERRASVASPGEKGECGVPWREG----- 330
+R + + GE+G+ G P G P + +PGEKG GVP G
Sbjct: 926 QRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP-GLKGFAGNPGEKGNRGVPGMPGLKGLK 984
Query: 331 ---GVWRPLDRRGSVASPGEKGECGVR 354
G P RG + S G GE G+R
Sbjct: 985 GLPGPAGPPGPRGDLGSTGNPGEPGLR 1011
Score = 78.2 bits (191), Expect = 1e-14
Identities = 89/311 (28%), Positives = 120/311 (38%), Gaps = 61/311 (19%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
PG++ P P G+ G++G GIP +GQ R + + GE+G+ G P
Sbjct: 897 PGAIGPPGP-------PGNPGTPGQRGSPGIPGVKGQ-------RGTPGAKGEQGDKGNP 942
Query: 131 WRE------GRVWRPLDRRGSVASPGEKGECGVPWREG-----------GVWRPLERRAS 173
G P +G +PGEKG GVP G G P S
Sbjct: 943 GPSEISHVIGDKGEP-GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS 1001
Query: 174 VASPGQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASP 233
+PG+ G G+P G + P S G++G G P R GR P
Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMP-------GSKGKRGTLGFPGRAGRPGLP----GIHGLQ 1050
Query: 234 GQKGECGV-----PWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVAS 288
G KGE G P GP P G G+KGE G P G + P + S
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDP----GLPGDMGKKGEMGQPGPPGHL-GPAGPEGAPGS 1105
Query: 289 PGEKGECGVPWTEGGV-WRPLERRASVASPGEKGECGVPWREG-----GVWRPLDRRGSV 342
PG G G P G + ++ + + + PG +G G+P G G+ R G
Sbjct: 1106 PGSPGLPGKPGPHGDLGFKGI--KGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIP 1163
Query: 343 ASPGEKGECGV 353
GEKGE G+
Sbjct: 1164 GPAGEKGETGL 1174
Score = 66.6 bits (161), Expect = 4e-11
Identities = 87/312 (27%), Positives = 114/312 (36%), Gaps = 58/312 (18%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
G G S + GE+G G+P T G P + G KG+ G P +E + LD +G
Sbjct: 121 GVPGCSGSKGEQGFPGLPGTLGYPGIP-------GAAGLKGQKGAPAKEEDI--ELDAKG 171
Query: 145 SVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVAS 204
PG G G+P G V PG G G P G P +G +
Sbjct: 172 DPGLPGAPGPQGLPGPPGFP-------GPVGPPGPPGFFGFP----GAMGPRGPKGHMGE 220
Query: 205 P--GEKGECGVPWREGRVWRPLERRASVASP----------GQKGECGVPWREGPVWRPL 252
G KGE GV G P ++ P G KG G P GP P
Sbjct: 221 RVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPG 280
Query: 253 ERRGSV-ASPGEKGECGVPWTEGGVWRPLER--RASVASPGEKGECGVPWTEGGVWRP-- 307
E GS +PG+ G G P +G P + + PG GE G+ +G + P
Sbjct: 281 ESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGF 340
Query: 308 ---------LERRASVASPGEKGECGVPWREG-----------GVWRPLDRRGSVASPGE 347
+ + +PG G G +G G RP RG+ PG
Sbjct: 341 RGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRP-GLRGAPGWPGL 399
Query: 348 KGECGVRWREGR 359
KG G R R G+
Sbjct: 400 KGSKGERGRPGK 411
Score = 65.5 bits (158), Expect = 8e-11
Identities = 84/320 (26%), Positives = 114/320 (35%), Gaps = 47/320 (14%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRP-----LERRASVASP---G 122
P +P P+ + G G + + G +G G+P G P V P G
Sbjct: 68 PEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSG 127
Query: 123 EKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGE 182
KGE G P G + P G + G KG+ G P +E + L+ + PG G
Sbjct: 128 SKGEQGFPGLPGTLGYP----GIPGAAGLKGQKGAPAKEEDI--ELDAKGDPGLPGAPGP 181
Query: 183 CGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVP 242
G+P G G V PG G G P G R + G KGE GV
Sbjct: 182 QGLPGPPG-------FPGPVGPPGPPGFFGFPGAMGP--RGPKGHMGERVIGHKGERGVK 232
Query: 243 WREGP----------VWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRAS-VASPGE 291
GP + P R G+KG G P G P E S +PG+
Sbjct: 233 GLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGD 292
Query: 292 KGECGVPWTEGGVWRPLER--RASVASPGEKGECGVPWREGGVWRP-----------LDR 338
G G P +G P + + PG GE G+ ++G + P
Sbjct: 293 PGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQE 352
Query: 339 RGSVASPGEKGECGVRWREG 358
+G +PG G G R +G
Sbjct: 353 KGDEGTPGPPGPRGARGPQG 372
Score = 65.1 bits (157), Expect = 1e-10
Identities = 83/309 (26%), Positives = 112/309 (36%), Gaps = 51/309 (16%)
Query: 67 LSAKPGSVPAP--------RPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASV 118
L KPG P + R G G G+KG+ G P G P E +
Sbjct: 295 LQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRG----PTEYYDTY 350
Query: 119 ASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPG 178
G++G G P RG+ G G GVP G L R + PG
Sbjct: 351 QEKGDEGTPGPP----------GPRGARGPQGPSGPPGVPGSPGSSRPGL--RGAPGWPG 398
Query: 179 QKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLE---RRASVAS--- 232
KG G R G + G+ SPG G G+P G P + R+
Sbjct: 399 LKGSKGERGRPGK-----DAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGL 453
Query: 233 PGQKGECGVPWREGPVWRP-LERRGSVASPGEKGECGVPWTEGGVWRPLERRAS--VASP 289
PG G G+P +GP P L PG G G+P G P + A+ SP
Sbjct: 454 PGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSP 513
Query: 290 GEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKG 349
G G G+P G PG +G+ G+ +G +P + G PG +G
Sbjct: 514 GSPGNTGLPGFPG-------------FPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRG 560
Query: 350 ECGVRWREG 358
+ G + +G
Sbjct: 561 QPGRKGLDG 569
Score = 61.6 bits (148), Expect = 1e-09
Identities = 84/301 (27%), Positives = 113/301 (37%), Gaps = 41/301 (13%)
Query: 92 AAGEKGECGIPWTEGQVWRPLER--RASVASPGEKGECGVPWREGRVWRPLDRRGSVASP 149
A GEKGE G P G P ++ PG +G G P G + RG P
Sbjct: 44 AKGEKGEKGFPGPPGS---PGQKGFTGPEGLPGPQGPKGFPGLPG-LTGSKGVRGISGLP 99
Query: 150 GEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVASPGEKG 209
G G G+P G P G KGE G P G + P G + G KG
Sbjct: 100 GFSGSPGLPGTPGNT-GPYGLVGVPGCSGSKGEQGFPGLPGTLGYP----GIPGAAGLKG 154
Query: 210 ECGVPWREGRVWRPLERRASV-ASPGQKGECGVPWREGPVWRP-----------LERRGS 257
+ G P +E + + + +PG +G G P GPV P + RG
Sbjct: 155 QKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP 214
Query: 258 VASPGE-----KGECGVPWTEGGVWRPLERRASVASP----------GEKGECGVPWTEG 302
GE KGE GV G P ++ P G+KG G P G
Sbjct: 215 KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274
Query: 303 GVWRPLERRAS-VASPGEKGECGVPWREGGVWRPLDR--RGSVASPGEKGECGVRWREGR 359
P E S +PG+ G G P ++G P +G+ PG GE G++ ++G
Sbjct: 275 PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGD 334
Query: 360 V 360
+
Sbjct: 335 I 335
Score = 52.8 bits (125), Expect = 5e-07
Identities = 54/183 (29%), Positives = 66/183 (36%), Gaps = 22/183 (12%)
Query: 94 GEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKG 153
G+KG G P +G P + PG G G P G P G PG KG
Sbjct: 1268 GDKGSMGHPGPKG----PPGTAGDMGPPGRLGAPGTPGLPG----PRGDPGFQGFPGVKG 1319
Query: 154 ECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG--GVWRPLERRGSVASPGEKGEC 211
E G P G S+ PG G G P G G + + GS PG GE
Sbjct: 1320 EKGNPGFLG----------SIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEP 1369
Query: 212 GVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPW 271
G+ G P G+ G+ G P GP +GS PG G G+P
Sbjct: 1370 GMQGEPGPPGPP-GNLGPCGPRGKPGKDGKPGTPGPAGEK-GNKGSKGEPGPAGSDGLPG 1427
Query: 272 TEG 274
+G
Sbjct: 1428 LKG 1430
Score = 41.2 bits (95), Expect = 0.002
Identities = 45/151 (29%), Positives = 58/151 (38%), Gaps = 21/151 (13%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
PG +P PR G+ G G KGE G P G + P G KG GV
Sbjct: 1300 PG-LPGPR------GDPGFQGFPGVKGEKGNPGFLGSIGPP-------GPIGPKGPPGVR 1345
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRP--LERRASVASPGQKGECGVPWR 188
G + + + GS PG GE G+ G P L PG+ G+ G P
Sbjct: 1346 GDPGTL-KIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGP 1404
Query: 189 EGGVWRPLERRGSVASPGEKGECGVPWREGR 219
G +GS PG G G+P +G+
Sbjct: 1405 AG----EKGNKGSKGEPGPAGSDGLPGLKGK 1431
>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
sapiens]
Length = 1670
Score = 89.4 bits (220), Expect = 5e-18
Identities = 88/297 (29%), Positives = 123/297 (41%), Gaps = 35/297 (11%)
Query: 80 LRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRP 139
L + G+ G G KG+ GIP + PGE G G+P +G + P
Sbjct: 822 LNGLKGQQGRRGKTGPKGDPGIPGLDRS-----------GFPGETGSPGIPGHQGEM-GP 869
Query: 140 LDRRGSVASP---GEKGECGVPWREG--GVWRPLERRASVASPGQKGECGVPWREGGVWR 194
L +RG +P G GE GV G G P + +PGQ+G G+P +G
Sbjct: 870 LGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929
Query: 195 PLER--RGSVASPGEK------GECGVPWREGRVWRPLER--RASVASPGQKGECGVPWR 244
P + +G +PG G+ G P +G P E+ R PG KG G+P
Sbjct: 930 PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989
Query: 245 EGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRP--LERRASVASPGEKGECGVPWTEG 302
GP P GS +PGE G G+P + G + P +R ++ PG G G+P G
Sbjct: 990 AGPP-GPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHG 1048
Query: 303 GVWRPLERRASVAS-PGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
E S + PG G G P G+ + ++G + PG G G EG
Sbjct: 1049 LQGDKGEPGYSEGTRPGPPGPTGDP----GLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101
Score = 84.3 bits (207), Expect = 2e-16
Identities = 88/312 (28%), Positives = 117/312 (37%), Gaps = 44/312 (14%)
Query: 62 TTSAFLSAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASP 121
T ++ PG +P L + G G AAG KG G P G P P
Sbjct: 477 TQCPYIPGPPG-LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFP-------GFP 528
Query: 122 GEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREG--------GVWRPLERRAS 173
G +G+ G+ +G +P G V PG+ G G P R+G GV +
Sbjct: 529 GAQGDPGLKGEKGETLQP---EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGE 585
Query: 174 VASPGQKGECGVPWREGGVWRP----------LERRGSVASPGEKGECGVPWREGRVWRP 223
+A G+KG+ G P G P +G G +G G P G
Sbjct: 586 LALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPR 645
Query: 224 LERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRP-LER 282
E S PG G G P GP +G PG G+CG P G P +
Sbjct: 646 GELSVSTPVPGPPGPPGPPGHPGP-------QGPPGIPGSLGKCGDPGLPGPDGEPGIPG 698
Query: 283 RASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREG--GVWRPLDRRG 340
PG KG+ G P T+G + P + PG G+ G+P +G V P G
Sbjct: 699 IGFPGPPGPKGDQGFPGTKGSLGCP----GKMGEPGLPGKPGLPGAKGEPAVAMP-GGPG 753
Query: 341 SVASPGEKGECG 352
+ PGE+G G
Sbjct: 754 TPGFPGERGNSG 765
Score = 80.1 bits (196), Expect = 3e-15
Identities = 88/293 (30%), Positives = 110/293 (37%), Gaps = 46/293 (15%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
PGS P P +R G G AGEKGE G+ + P R + + G KG+ G P
Sbjct: 1145 PGS-PGPMGIRGDQGRDGIPGPAGEKGETGL------LRAPPGPRGNPGAQGAKGDRGAP 1197
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
G R+G++ G +G G+ G P PGQ G G P G
Sbjct: 1198 GFPGLP----GRKGAMGDAGPRGPTGIEGFPGPPGLP-----GAIIPGQTGNRGPPGSRG 1248
Query: 191 --GVWRPLERRGS--VASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREG 246
G P GS + G+KG G P +G P + PG+ G G P G
Sbjct: 1249 SPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKG----PPGTAGDMGPPGRLGAPGTPGLPG 1304
Query: 247 PVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWR 306
P P G PG KGE G P G S+ PG G G P G
Sbjct: 1305 PRGDP----GFQGFPGVKGEKGNPGFLG----------SIGPPGPIGPKGPPGVRGDP-G 1349
Query: 307 PLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREGR 359
L+ + SPG G G P +G G PG G CG R + G+
Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQG-------EPGPPGPPGNLGPCGPRGKPGK 1395
Score = 78.6 bits (192), Expect = 9e-15
Identities = 94/327 (28%), Positives = 127/327 (38%), Gaps = 67/327 (20%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASV-------------ASP 121
P P+ + G G G+ GE G+P G E ++ +
Sbjct: 705 PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNS 764
Query: 122 GEKGECGVPWREGRVWRPLDR-----RGSVASPGEKGECGVPWR--EGGVWRPLERRASV 174
GE GE G+P G P + RG PG GE G P R EG P +
Sbjct: 765 GEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG----PRGAQGLP 820
Query: 175 ASPGQKGECGVPWREGGVWRP----LERRGSVASPGEKGECGVPWREGRVWRPLERRASV 230
G KG+ G + G P L+R G PGE G G+P +G + PL +R
Sbjct: 821 GLNGLKGQQGRRGKTGPKGDPGIPGLDRSG---FPGETGSPGIPGHQGEM-GPLGQRGYP 876
Query: 231 ASP---GQKGECGV------PWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLE 281
+P G GE GV P GP P G+ +PG++G G+P +G
Sbjct: 877 GNPGILGPPGEDGVIGMMGFPGAIGPPGPP----GNPGTPGQRGSPGIPGVKG------- 925
Query: 282 RRASVASPGEKGECGVPWTE------GGVWRPLERRASVASPGEKGECGVPWREG----- 330
+R + + GE+G+ G P G P + +PGEKG GVP G
Sbjct: 926 QRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP-GLKGFAGNPGEKGNRGVPGMPGLKGLK 984
Query: 331 ---GVWRPLDRRGSVASPGEKGECGVR 354
G P RG + S G GE G+R
Sbjct: 985 GLPGPAGPPGPRGDLGSTGNPGEPGLR 1011
Score = 78.2 bits (191), Expect = 1e-14
Identities = 89/311 (28%), Positives = 120/311 (38%), Gaps = 61/311 (19%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
PG++ P P G+ G++G GIP +GQ R + + GE+G+ G P
Sbjct: 897 PGAIGPPGP-------PGNPGTPGQRGSPGIPGVKGQ-------RGTPGAKGEQGDKGNP 942
Query: 131 WRE------GRVWRPLDRRGSVASPGEKGECGVPWREG-----------GVWRPLERRAS 173
G P +G +PGEKG GVP G G P S
Sbjct: 943 GPSEISHVIGDKGEP-GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS 1001
Query: 174 VASPGQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASP 233
+PG+ G G+P G + P S G++G G P R GR P
Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMP-------GSKGKRGTLGFPGRAGRPGLP----GIHGLQ 1050
Query: 234 GQKGECGV-----PWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVAS 288
G KGE G P GP P G G+KGE G P G + P + S
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDP----GLPGDMGKKGEMGQPGPPGHL-GPAGPEGAPGS 1105
Query: 289 PGEKGECGVPWTEGGV-WRPLERRASVASPGEKGECGVPWREG-----GVWRPLDRRGSV 342
PG G G P G + ++ + + + PG +G G+P G G+ R G
Sbjct: 1106 PGSPGLPGKPGPHGDLGFKGI--KGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIP 1163
Query: 343 ASPGEKGECGV 353
GEKGE G+
Sbjct: 1164 GPAGEKGETGL 1174
Score = 66.6 bits (161), Expect = 4e-11
Identities = 87/312 (27%), Positives = 114/312 (36%), Gaps = 58/312 (18%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRG 144
G G S + GE+G G+P T G P + G KG+ G P +E + LD +G
Sbjct: 121 GVPGCSGSKGEQGFPGLPGTLGYPGIP-------GAAGLKGQKGAPAKEEDI--ELDAKG 171
Query: 145 SVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVAS 204
PG G G+P G V PG G G P G P +G +
Sbjct: 172 DPGLPGAPGPQGLPGPPGFP-------GPVGPPGPPGFFGFP----GAMGPRGPKGHMGE 220
Query: 205 P--GEKGECGVPWREGRVWRPLERRASVASP----------GQKGECGVPWREGPVWRPL 252
G KGE GV G P ++ P G KG G P GP P
Sbjct: 221 RVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPG 280
Query: 253 ERRGSV-ASPGEKGECGVPWTEGGVWRPLER--RASVASPGEKGECGVPWTEGGVWRP-- 307
E GS +PG+ G G P +G P + + PG GE G+ +G + P
Sbjct: 281 ESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGF 340
Query: 308 ---------LERRASVASPGEKGECGVPWREG-----------GVWRPLDRRGSVASPGE 347
+ + +PG G G +G G RP RG+ PG
Sbjct: 341 RGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRP-GLRGAPGWPGL 399
Query: 348 KGECGVRWREGR 359
KG G R R G+
Sbjct: 400 KGSKGERGRPGK 411
Score = 65.5 bits (158), Expect = 8e-11
Identities = 84/320 (26%), Positives = 114/320 (35%), Gaps = 47/320 (14%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRP-----LERRASVASP---G 122
P +P P+ + G G + + G +G G+P G P V P G
Sbjct: 68 PEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSG 127
Query: 123 EKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGE 182
KGE G P G + P G + G KG+ G P +E + L+ + PG G
Sbjct: 128 SKGEQGFPGLPGTLGYP----GIPGAAGLKGQKGAPAKEEDI--ELDAKGDPGLPGAPGP 181
Query: 183 CGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVP 242
G+P G G V PG G G P G R + G KGE GV
Sbjct: 182 QGLPGPPG-------FPGPVGPPGPPGFFGFPGAMGP--RGPKGHMGERVIGHKGERGVK 232
Query: 243 WREGP----------VWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRAS-VASPGE 291
GP + P R G+KG G P G P E S +PG+
Sbjct: 233 GLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGD 292
Query: 292 KGECGVPWTEGGVWRPLER--RASVASPGEKGECGVPWREGGVWRP-----------LDR 338
G G P +G P + + PG GE G+ ++G + P
Sbjct: 293 PGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQE 352
Query: 339 RGSVASPGEKGECGVRWREG 358
+G +PG G G R +G
Sbjct: 353 KGDEGTPGPPGPRGARGPQG 372
Score = 65.1 bits (157), Expect = 1e-10
Identities = 83/309 (26%), Positives = 112/309 (36%), Gaps = 51/309 (16%)
Query: 67 LSAKPGSVPAP--------RPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASV 118
L KPG P + R G G G+KG+ G P G P E +
Sbjct: 295 LQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRG----PTEYYDTY 350
Query: 119 ASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPG 178
G++G G P RG+ G G GVP G L R + PG
Sbjct: 351 QEKGDEGTPGPP----------GPRGARGPQGPSGPPGVPGSPGSSRPGL--RGAPGWPG 398
Query: 179 QKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLE---RRASVAS--- 232
KG G R G + G+ SPG G G+P G P + R+
Sbjct: 399 LKGSKGERGRPGK-----DAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGL 453
Query: 233 PGQKGECGVPWREGPVWRP-LERRGSVASPGEKGECGVPWTEGGVWRPLERRAS--VASP 289
PG G G+P +GP P L PG G G+P G P + A+ SP
Sbjct: 454 PGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSP 513
Query: 290 GEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKG 349
G G G+P G PG +G+ G+ +G +P + G PG +G
Sbjct: 514 GSPGNTGLPGFPG-------------FPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRG 560
Query: 350 ECGVRWREG 358
+ G + +G
Sbjct: 561 QPGRKGLDG 569
Score = 61.6 bits (148), Expect = 1e-09
Identities = 84/301 (27%), Positives = 113/301 (37%), Gaps = 41/301 (13%)
Query: 92 AAGEKGECGIPWTEGQVWRPLER--RASVASPGEKGECGVPWREGRVWRPLDRRGSVASP 149
A GEKGE G P G P ++ PG +G G P G + RG P
Sbjct: 44 AKGEKGEKGFPGPPGS---PGQKGFTGPEGLPGPQGPKGFPGLPG-LTGSKGVRGISGLP 99
Query: 150 GEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVASPGEKG 209
G G G+P G P G KGE G P G + P G + G KG
Sbjct: 100 GFSGSPGLPGTPGNT-GPYGLVGVPGCSGSKGEQGFPGLPGTLGYP----GIPGAAGLKG 154
Query: 210 ECGVPWREGRVWRPLERRASV-ASPGQKGECGVPWREGPVWRP-----------LERRGS 257
+ G P +E + + + +PG +G G P GPV P + RG
Sbjct: 155 QKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP 214
Query: 258 VASPGE-----KGECGVPWTEGGVWRPLERRASVASP----------GEKGECGVPWTEG 302
GE KGE GV G P ++ P G+KG G P G
Sbjct: 215 KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274
Query: 303 GVWRPLERRAS-VASPGEKGECGVPWREGGVWRPLDR--RGSVASPGEKGECGVRWREGR 359
P E S +PG+ G G P ++G P +G+ PG GE G++ ++G
Sbjct: 275 PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGD 334
Query: 360 V 360
+
Sbjct: 335 I 335
Score = 52.8 bits (125), Expect = 5e-07
Identities = 54/183 (29%), Positives = 66/183 (36%), Gaps = 22/183 (12%)
Query: 94 GEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDRRGSVASPGEKG 153
G+KG G P +G P + PG G G P G P G PG KG
Sbjct: 1268 GDKGSMGHPGPKG----PPGTAGDMGPPGRLGAPGTPGLPG----PRGDPGFQGFPGVKG 1319
Query: 154 ECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG--GVWRPLERRGSVASPGEKGEC 211
E G P G S+ PG G G P G G + + GS PG GE
Sbjct: 1320 EKGNPGFLG----------SIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEP 1369
Query: 212 GVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPW 271
G+ G P G+ G+ G P GP +GS PG G G+P
Sbjct: 1370 GMQGEPGPPGPP-GNLGPCGPRGKPGKDGKPGTPGPAGEK-GNKGSKGEPGPAGSDGLPG 1427
Query: 272 TEG 274
+G
Sbjct: 1428 LKG 1430
Score = 41.2 bits (95), Expect = 0.002
Identities = 45/151 (29%), Positives = 58/151 (38%), Gaps = 21/151 (13%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
PG +P PR G+ G G KGE G P G + P G KG GV
Sbjct: 1300 PG-LPGPR------GDPGFQGFPGVKGEKGNPGFLGSIGPP-------GPIGPKGPPGVR 1345
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRP--LERRASVASPGQKGECGVPWR 188
G + + + GS PG GE G+ G P L PG+ G+ G P
Sbjct: 1346 GDPGTL-KIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGP 1404
Query: 189 EGGVWRPLERRGSVASPGEKGECGVPWREGR 219
G +GS PG G G+P +G+
Sbjct: 1405 AG----EKGNKGSKGEPGPAGSDGLPGLKGK 1431
>gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo
sapiens]
Length = 2971
Score = 88.6 bits (218), Expect = 9e-18
Identities = 85/286 (29%), Positives = 110/286 (38%), Gaps = 44/286 (15%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDR-- 142
G+ G G G GIP +G P + PGE+G GV +G P R
Sbjct: 1832 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDE----GGPGERGPPGVNGTQGFQGCPGQRGV 1887
Query: 143 RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSV 202
+GS PGEKGE G +G ++ PG GE G P R G +G
Sbjct: 1888 KGSRGFPGEKGEVGEIGLDGLDGEDGDK----GLPGSSGEKGNPGRRGD-------KGPR 1936
Query: 203 ASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLE--------R 254
GE+G+ G+ G + + R G G GVP R+G P E R
Sbjct: 1937 GEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGR 1996
Query: 255 RGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEG--GVWRPLERRA 312
RG + G KG G P EG + + + G G G P G G+ P
Sbjct: 1997 RGPPGAKGNKGGPGQPGFEG-------EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGG 2049
Query: 313 SVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
+ +PGE+G G PL R+G PG KG G R G
Sbjct: 2050 AAGAPGERGRTG----------PLGRKGEPGEPGPKGGIGNRGPRG 2085
Score = 75.5 bits (184), Expect = 8e-14
Identities = 86/280 (30%), Positives = 107/280 (38%), Gaps = 41/280 (14%)
Query: 80 LRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRP 139
L +DGE G G GE G P G + GE+G+ G+ G +
Sbjct: 1905 LDGLDGEDGDKGLPGSSGEKGNPGRRGD-------KGPRGEKGERGDVGIRGDPGNPGQD 1957
Query: 140 LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERR 199
RG G+ G GVP R+G PG GE G + GG RR
Sbjct: 1958 SQERGPKGETGDLGPMGVPGRDG-------------VPGGPGETG---KNGG----FGRR 1997
Query: 200 GSVASPGEKGECGVPWREG-RVWRPLERRASVASP----GQKGECGVPWREGPVWRPLER 254
G + G KG G P EG + R + A A P G++G G G P E
Sbjct: 1998 GPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE- 2056
Query: 255 RGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASV 314
RG G KGE G P +GG+ R G+ G GV +EG + E R
Sbjct: 2057 RGRTGPLGRKGEPGEPGPKGGI----GNRGPRGETGDDGRDGV-GSEGRRGKKGE-RGFP 2110
Query: 315 ASPGEKGECGVPWREG--GVWRPLDRRGSVASPGEKGECG 352
PG KG G P G G RRG+ PG G+ G
Sbjct: 2111 GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKG 2150
Score = 74.7 bits (182), Expect = 1e-13
Identities = 73/256 (28%), Positives = 97/256 (37%), Gaps = 40/256 (15%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRP----- 139
G+ G GE+G+ GI G + + R G+ G GVP R+G P
Sbjct: 1931 GDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGK 1990
Query: 140 ---LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPW--REGGVWR 194
RRG + G KG G P EG + + + G G G P E G+
Sbjct: 1991 NGGFGRRGPPGAKGNKGGPGQPGFEG-------EQGTRGAQGPAGPAGPPGLIGEQGISG 2043
Query: 195 PLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLER 254
P G+ +PGE+G G R+G P + + + G +GE G R+G
Sbjct: 2044 PRGSGGAAGAPGERGRTGPLGRKGEPGEP-GPKGGIGNRGPRGETGDDGRDGV------- 2095
Query: 255 RGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASV 314
GS G+KGE G P G P E PG G G G RR +
Sbjct: 2096 -GSEGRRGKKGERGFPGYPGPKGNPGE-------PGLNGTTGPKGIRG-------RRGNS 2140
Query: 315 ASPGEKGECGVPWREG 330
PG G+ G P G
Sbjct: 2141 GPPGIVGQKGDPGYPG 2156
Score = 61.2 bits (147), Expect = 2e-09
Identities = 61/216 (28%), Positives = 82/216 (37%), Gaps = 46/216 (21%)
Query: 151 EKGECGVPWR---EGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVASPGE 207
EK CGVP + + G P+ PG+ G G P EGG PGE
Sbjct: 1820 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGG-------------PGE 1866
Query: 208 KGECGVPWREGRVWRPLER--RASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKG 265
+G GV +G P +R + S PG+KGE G +G GE G
Sbjct: 1867 RGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDG-------------LDGEDG 1913
Query: 266 ECGVPWTEGGVWRPLER--RASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGEC 323
+ G+P + G P R + GE+G+ G+ G + + R G+ G
Sbjct: 1914 DKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPM 1973
Query: 324 GVPWREGGVWRPLDRRGSVASPGEKGECGVRWREGR 359
GVP R+G PG GE G GR
Sbjct: 1974 GVPGRDG-------------VPGGPGETGKNGGFGR 1996
Score = 53.1 bits (126), Expect = 4e-07
Identities = 50/164 (30%), Positives = 66/164 (40%), Gaps = 23/164 (14%)
Query: 207 EKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGE 266
EK CGVP + +R G G G+P +G P G PGE+G
Sbjct: 1820 EKACCGVPCKCSG------QRGDRGPIGSIGPKGIPGEDGYRGYP----GDEGGPGERGP 1869
Query: 267 CGVPWTEGGVWRPLER--RASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECG 324
GV T+G P +R + S PGEKGE G +G ++ PG GE G
Sbjct: 1870 PGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDK----GLPGSSGEKG 1925
Query: 325 VPWREGGVWRPLDRRGSVASPGEKGECGVRWREGRVWYSLDKRG 368
P R G +G GE+G+ G+R G +RG
Sbjct: 1926 NPGRRGD-------KGPRGEKGERGDVGIRGDPGNPGQDSQERG 1962
>gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
sapiens]
Length = 3177
Score = 88.6 bits (218), Expect = 9e-18
Identities = 85/286 (29%), Positives = 110/286 (38%), Gaps = 44/286 (15%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDR-- 142
G+ G G G GIP +G P + PGE+G GV +G P R
Sbjct: 2038 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDE----GGPGERGPPGVNGTQGFQGCPGQRGV 2093
Query: 143 RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSV 202
+GS PGEKGE G +G ++ PG GE G P R G +G
Sbjct: 2094 KGSRGFPGEKGEVGEIGLDGLDGEDGDK----GLPGSSGEKGNPGRRGD-------KGPR 2142
Query: 203 ASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLE--------R 254
GE+G+ G+ G + + R G G GVP R+G P E R
Sbjct: 2143 GEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGR 2202
Query: 255 RGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEG--GVWRPLERRA 312
RG + G KG G P EG + + + G G G P G G+ P
Sbjct: 2203 RGPPGAKGNKGGPGQPGFEG-------EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGG 2255
Query: 313 SVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
+ +PGE+G G PL R+G PG KG G R G
Sbjct: 2256 AAGAPGERGRTG----------PLGRKGEPGEPGPKGGIGNRGPRG 2291
Score = 75.5 bits (184), Expect = 8e-14
Identities = 86/280 (30%), Positives = 107/280 (38%), Gaps = 41/280 (14%)
Query: 80 LRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRP 139
L +DGE G G GE G P G + GE+G+ G+ G +
Sbjct: 2111 LDGLDGEDGDKGLPGSSGEKGNPGRRGD-------KGPRGEKGERGDVGIRGDPGNPGQD 2163
Query: 140 LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERR 199
RG G+ G GVP R+G PG GE G + GG RR
Sbjct: 2164 SQERGPKGETGDLGPMGVPGRDG-------------VPGGPGETG---KNGG----FGRR 2203
Query: 200 GSVASPGEKGECGVPWREG-RVWRPLERRASVASP----GQKGECGVPWREGPVWRPLER 254
G + G KG G P EG + R + A A P G++G G G P E
Sbjct: 2204 GPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE- 2262
Query: 255 RGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASV 314
RG G KGE G P +GG+ R G+ G GV +EG + E R
Sbjct: 2263 RGRTGPLGRKGEPGEPGPKGGI----GNRGPRGETGDDGRDGV-GSEGRRGKKGE-RGFP 2316
Query: 315 ASPGEKGECGVPWREG--GVWRPLDRRGSVASPGEKGECG 352
PG KG G P G G RRG+ PG G+ G
Sbjct: 2317 GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKG 2356
Score = 74.7 bits (182), Expect = 1e-13
Identities = 73/256 (28%), Positives = 97/256 (37%), Gaps = 40/256 (15%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRP----- 139
G+ G GE+G+ GI G + + R G+ G GVP R+G P
Sbjct: 2137 GDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGK 2196
Query: 140 ---LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPW--REGGVWR 194
RRG + G KG G P EG + + + G G G P E G+
Sbjct: 2197 NGGFGRRGPPGAKGNKGGPGQPGFEG-------EQGTRGAQGPAGPAGPPGLIGEQGISG 2249
Query: 195 PLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLER 254
P G+ +PGE+G G R+G P + + + G +GE G R+G
Sbjct: 2250 PRGSGGAAGAPGERGRTGPLGRKGEPGEP-GPKGGIGNRGPRGETGDDGRDGV------- 2301
Query: 255 RGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASV 314
GS G+KGE G P G P E PG G G G RR +
Sbjct: 2302 -GSEGRRGKKGERGFPGYPGPKGNPGE-------PGLNGTTGPKGIRG-------RRGNS 2346
Query: 315 ASPGEKGECGVPWREG 330
PG G+ G P G
Sbjct: 2347 GPPGIVGQKGDPGYPG 2362
Score = 61.2 bits (147), Expect = 2e-09
Identities = 61/216 (28%), Positives = 82/216 (37%), Gaps = 46/216 (21%)
Query: 151 EKGECGVPWR---EGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVASPGE 207
EK CGVP + + G P+ PG+ G G P EGG PGE
Sbjct: 2026 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGG-------------PGE 2072
Query: 208 KGECGVPWREGRVWRPLER--RASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKG 265
+G GV +G P +R + S PG+KGE G +G GE G
Sbjct: 2073 RGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDG-------------LDGEDG 2119
Query: 266 ECGVPWTEGGVWRPLER--RASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGEC 323
+ G+P + G P R + GE+G+ G+ G + + R G+ G
Sbjct: 2120 DKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPM 2179
Query: 324 GVPWREGGVWRPLDRRGSVASPGEKGECGVRWREGR 359
GVP R+G PG GE G GR
Sbjct: 2180 GVPGRDG-------------VPGGPGETGKNGGFGR 2202
Score = 53.1 bits (126), Expect = 4e-07
Identities = 50/164 (30%), Positives = 66/164 (40%), Gaps = 23/164 (14%)
Query: 207 EKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGE 266
EK CGVP + +R G G G+P +G P G PGE+G
Sbjct: 2026 EKACCGVPCKCSG------QRGDRGPIGSIGPKGIPGEDGYRGYP----GDEGGPGERGP 2075
Query: 267 CGVPWTEGGVWRPLER--RASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECG 324
GV T+G P +R + S PGEKGE G +G ++ PG GE G
Sbjct: 2076 PGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDK----GLPGSSGEKG 2131
Query: 325 VPWREGGVWRPLDRRGSVASPGEKGECGVRWREGRVWYSLDKRG 368
P R G +G GE+G+ G+R G +RG
Sbjct: 2132 NPGRRGD-------KGPRGEKGERGDVGIRGDPGNPGQDSQERG 2168
>gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo
sapiens]
Length = 2570
Score = 88.6 bits (218), Expect = 9e-18
Identities = 85/286 (29%), Positives = 110/286 (38%), Gaps = 44/286 (15%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRPLDR-- 142
G+ G G G GIP +G P + PGE+G GV +G P R
Sbjct: 1431 GQRGDRGPIGSIGPKGIPGEDGYRGYPGDE----GGPGERGPPGVNGTQGFQGCPGQRGV 1486
Query: 143 RGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSV 202
+GS PGEKGE G +G ++ PG GE G P R G +G
Sbjct: 1487 KGSRGFPGEKGEVGEIGLDGLDGEDGDK----GLPGSSGEKGNPGRRGD-------KGPR 1535
Query: 203 ASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLE--------R 254
GE+G+ G+ G + + R G G GVP R+G P E R
Sbjct: 1536 GEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGR 1595
Query: 255 RGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEG--GVWRPLERRA 312
RG + G KG G P EG + + + G G G P G G+ P
Sbjct: 1596 RGPPGAKGNKGGPGQPGFEG-------EQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGG 1648
Query: 313 SVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
+ +PGE+G G PL R+G PG KG G R G
Sbjct: 1649 AAGAPGERGRTG----------PLGRKGEPGEPGPKGGIGNRGPRG 1684
Score = 75.5 bits (184), Expect = 8e-14
Identities = 86/280 (30%), Positives = 107/280 (38%), Gaps = 41/280 (14%)
Query: 80 LRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRP 139
L +DGE G G GE G P G + GE+G+ G+ G +
Sbjct: 1504 LDGLDGEDGDKGLPGSSGEKGNPGRRGD-------KGPRGEKGERGDVGIRGDPGNPGQD 1556
Query: 140 LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERR 199
RG G+ G GVP R+G PG GE G + GG RR
Sbjct: 1557 SQERGPKGETGDLGPMGVPGRDG-------------VPGGPGETG---KNGG----FGRR 1596
Query: 200 GSVASPGEKGECGVPWREG-RVWRPLERRASVASP----GQKGECGVPWREGPVWRPLER 254
G + G KG G P EG + R + A A P G++G G G P E
Sbjct: 1597 GPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGE- 1655
Query: 255 RGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASV 314
RG G KGE G P +GG+ R G+ G GV +EG + E R
Sbjct: 1656 RGRTGPLGRKGEPGEPGPKGGI----GNRGPRGETGDDGRDGV-GSEGRRGKKGE-RGFP 1709
Query: 315 ASPGEKGECGVPWREG--GVWRPLDRRGSVASPGEKGECG 352
PG KG G P G G RRG+ PG G+ G
Sbjct: 1710 GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKG 1749
Score = 74.7 bits (182), Expect = 1e-13
Identities = 73/256 (28%), Positives = 97/256 (37%), Gaps = 40/256 (15%)
Query: 85 GEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREGRVWRP----- 139
G+ G GE+G+ GI G + + R G+ G GVP R+G P
Sbjct: 1530 GDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGK 1589
Query: 140 ---LDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPW--REGGVWR 194
RRG + G KG G P EG + + + G G G P E G+
Sbjct: 1590 NGGFGRRGPPGAKGNKGGPGQPGFEG-------EQGTRGAQGPAGPAGPPGLIGEQGISG 1642
Query: 195 PLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLER 254
P G+ +PGE+G G R+G P + + + G +GE G R+G
Sbjct: 1643 PRGSGGAAGAPGERGRTGPLGRKGEPGEP-GPKGGIGNRGPRGETGDDGRDGV------- 1694
Query: 255 RGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPLERRASV 314
GS G+KGE G P G P E PG G G G RR +
Sbjct: 1695 -GSEGRRGKKGERGFPGYPGPKGNPGE-------PGLNGTTGPKGIRG-------RRGNS 1739
Query: 315 ASPGEKGECGVPWREG 330
PG G+ G P G
Sbjct: 1740 GPPGIVGQKGDPGYPG 1755
Score = 61.2 bits (147), Expect = 2e-09
Identities = 61/216 (28%), Positives = 82/216 (37%), Gaps = 46/216 (21%)
Query: 151 EKGECGVPWR---EGGVWRPLERRASVASPGQKGECGVPWREGGVWRPLERRGSVASPGE 207
EK CGVP + + G P+ PG+ G G P EGG PGE
Sbjct: 1419 EKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGG-------------PGE 1465
Query: 208 KGECGVPWREGRVWRPLER--RASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKG 265
+G GV +G P +R + S PG+KGE G +G GE G
Sbjct: 1466 RGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDG-------------LDGEDG 1512
Query: 266 ECGVPWTEGGVWRPLER--RASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGEC 323
+ G+P + G P R + GE+G+ G+ G + + R G+ G
Sbjct: 1513 DKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPM 1572
Query: 324 GVPWREGGVWRPLDRRGSVASPGEKGECGVRWREGR 359
GVP R+G PG GE G GR
Sbjct: 1573 GVPGRDG-------------VPGGPGETGKNGGFGR 1595
Score = 53.1 bits (126), Expect = 4e-07
Identities = 50/164 (30%), Positives = 66/164 (40%), Gaps = 23/164 (14%)
Query: 207 EKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWRPLERRGSVASPGEKGE 266
EK CGVP + +R G G G+P +G P G PGE+G
Sbjct: 1419 EKACCGVPCKCSG------QRGDRGPIGSIGPKGIPGEDGYRGYP----GDEGGPGERGP 1468
Query: 267 CGVPWTEGGVWRPLER--RASVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECG 324
GV T+G P +R + S PGEKGE G +G ++ PG GE G
Sbjct: 1469 PGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDK----GLPGSSGEKG 1524
Query: 325 VPWREGGVWRPLDRRGSVASPGEKGECGVRWREGRVWYSLDKRG 368
P R G +G GE+G+ G+R G +RG
Sbjct: 1525 NPGRRGD-------KGPRGEKGERGDVGIRGDPGNPGQDSQERG 1561
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 88.2 bits (217), Expect = 1e-17
Identities = 89/292 (30%), Positives = 108/292 (36%), Gaps = 35/292 (11%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
PG P P+ G G G KGE G +G P + GE G G+P
Sbjct: 423 PGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPG-PAGEEGKRGARGEPGPTGLP 481
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGV--PWREGGVWRPLERRASVASPGQKGECGVPWR 188
G P GS PG G G P E G P + S G+ GE G+P
Sbjct: 482 GPPGERGGP----GSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGA 537
Query: 189 EGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPV 248
+G GS SPG G+ G P G+ RP PG +G+ GV GP
Sbjct: 538 KG-------LTGSPGSPGPDGKTGPPGPAGQDGRP----GPPGPPGARGQAGVMGFPGP- 585
Query: 249 WRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWRPL 308
+G+ PG+ GE GVP G V P + + G G G P E G P
Sbjct: 586 ------KGAAGEPGKAGERGVPGPPGAV-GPAGKDGEAGAQGPPGPAG-PAGERGEQGPA 637
Query: 309 ERRASVASP---GEKGECGVPWREG-----GVWRPLDRRGSVASPGEKGECG 352
P G GE G P +G G P RG PGE+G G
Sbjct: 638 GSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQG 689
Score = 87.8 bits (216), Expect = 2e-17
Identities = 90/300 (30%), Positives = 107/300 (35%), Gaps = 45/300 (15%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
P P P GE+G S AG G G P G+ P PG G+ G
Sbjct: 768 PIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPP-GPAGFAGPPGADGQPGAK 826
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLER--RASVASPGQKGECGVPWR 188
G +G PG G G P G V P + R S PG G G R
Sbjct: 827 GEPG----DAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGR 882
Query: 189 EG--------GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECG 240
G G P G G +GE G R G V P PG GE G
Sbjct: 883 VGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPP-------GPPGPAGEKG 935
Query: 241 VPWREGPVWRP--------LERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEK 292
P +GP P +RG V PG++GE G P G P ++ S AS GE+
Sbjct: 936 SPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGAS-GER 994
Query: 293 GECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECG 352
G G P+ PGE G G P EG R GS + G++GE G
Sbjct: 995 GPPG----------PMGPPGLAGPPGESGREGAPGAEGSP----GRDGSPGAKGDRGETG 1040
Score = 86.3 bits (212), Expect = 4e-17
Identities = 90/307 (29%), Positives = 114/307 (37%), Gaps = 55/307 (17%)
Query: 75 PAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVPWREG 134
P P R +G G+ A G+ G G P ++G PGE+G G+P +G
Sbjct: 691 PGPAGPRGANGAPGNDGAKGDAGAPGAPGSQG-------APGLQGMPGERGAAGLPGPKG 743
Query: 135 RVWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGVPWREGGV 192
DR G KG G P ++G G+ P+ +PG KGE G G
Sbjct: 744 ------DR----GDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESG----PSGP 789
Query: 193 WRPLERRGSVASPGEKGECGVPWREGRVWRP-----LERRASVASPGQKGECGVPWREGP 247
P RG +PG++GE G P G P + G KG+ G P GP
Sbjct: 790 AGPTGARG---APGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGP 846
Query: 248 VWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEG----- 302
P G+V +PG KG G G P V PG G G P G
Sbjct: 847 AGPP-GPIGNVGAPGAKGARGSAGPPGATGFP-GAAGRVGPPGPSGNAGPPGPPGPAGKE 904
Query: 303 ------GVWRPLERRASV---ASPGEKGECGVPWREGGVWRP--------LDRRGSVASP 345
G P R V PG GE G P +G P +RG V P
Sbjct: 905 GGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLP 964
Query: 346 GEKGECG 352
G++GE G
Sbjct: 965 GQRGERG 971
Score = 85.1 bits (209), Expect = 1e-16
Identities = 88/300 (29%), Positives = 106/300 (35%), Gaps = 42/300 (14%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLE-----RRASVASPGEKG 125
P P R G+ G G G G P +GQ E + PG G
Sbjct: 786 PSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAG 845
Query: 126 ECGVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGV 185
G P G V P +G+ S G G G P G V P + PG G G
Sbjct: 846 PAGPPGPIGNVGAP-GAKGARGSAGPPGATGFPGAAGRVGPP-GPSGNAGPPGPPGPAGK 903
Query: 186 PWREG--GVWRPLERRGSVASPGEKG---ECGVPWREGRVWRP--------LERRASVAS 232
+G G P R G V PG G E G P +G P +R V
Sbjct: 904 EGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGL 963
Query: 233 PGQKGECGVPWREGPVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEK 292
PGQ+GE G P GP P ++G + GE+G G P+ PGE
Sbjct: 964 PGQRGERGFPGLPGPSGEP-GKQGPSGASGERGPPG----------PMGPPGLAGPPGES 1012
Query: 293 GECGVPWTEGGVWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECG 352
G G P EG R SPG KG+ G E G P G+ +PG G G
Sbjct: 1013 GREGAPGAEGSPGRD-------GSPGAKGDRG----ETGPAGPPGAPGAPGAPGPVGPAG 1061
Score = 83.2 bits (204), Expect = 4e-16
Identities = 83/292 (28%), Positives = 101/292 (34%), Gaps = 34/292 (11%)
Query: 69 AKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECG 128
A P P P G G +AG G G P G+ V PG G G
Sbjct: 844 AGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGR----------VGPPGPSGNAG 893
Query: 129 VPWREGRVWRPLDRRGSVASPGEKGECGVPWREG--GVWRPLERRASVASPGQKGECGVP 186
P G P + G GE G G P G G P + S + G G G P
Sbjct: 894 PPGPPG----PAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTP 949
Query: 187 WREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREG 246
+G +RG V PG++GE G P G PG++G G G
Sbjct: 950 GPQG----IAGQRGVVGLPGQRGERGFPGLPG----------PSGEPGKQGPSGASGERG 995
Query: 247 PVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVWR 306
P P+ G PGE G G P EG R A GE G G P G
Sbjct: 996 PP-GPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAK-GDRGETGPAGPPGAPGAPGA 1053
Query: 307 PLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREG 358
P G++GE G P G P+ RG G +G+ G +G
Sbjct: 1054 P-GPVGPAGKSGDRGETG-PAGPAGPVGPVGARGPAGPQGPRGDKGETGEQG 1103
Score = 82.8 bits (203), Expect = 5e-16
Identities = 104/368 (28%), Positives = 123/368 (33%), Gaps = 67/368 (18%)
Query: 71 PGSVPAP-----RPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKG 125
PG+ P R +DG G + AG KGE G P G +PG+ G
Sbjct: 256 PGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENG-------------APGQMG 302
Query: 126 ECGVPWREGRVWRP--------LDRRGSVASPGEKGECGVPWREGGVWR-----PLERRA 172
G+P GR P G+ PG G G P G V P R
Sbjct: 303 PRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRG 362
Query: 173 SVASPGQKGECGVPWREGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRAS--- 229
S G +GE G P G P G+ PG KG G P G P R S
Sbjct: 363 SEGPQGVRGEPGPPGPAGAA-GPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQ 421
Query: 230 --------------VASPGQKGECGVPWREGPVW-----RPLERRGSVASPGEKGECGVP 270
+PG KG+ G GPV P G + GE G G+P
Sbjct: 422 GPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLP 481
Query: 271 WTEGGVWRPLER----RASVASP-GEKGECGVPWTEGGVWRPLE--RRASVASPGEKGEC 323
G P R VA P G GE G P G P E R PG KG
Sbjct: 482 GPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLT 541
Query: 324 GVPWREG--GVWRPLDRRGSVASPGEKGECGVRWREGRVWYSLDKRGSVPAALASQRHAL 381
G P G G P G PG G G R + G + + K + A +R
Sbjct: 542 GSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGER--- 598
Query: 382 LALPQPQG 389
+P P G
Sbjct: 599 -GVPGPPG 605
Score = 82.8 bits (203), Expect = 5e-16
Identities = 87/295 (29%), Positives = 113/295 (38%), Gaps = 48/295 (16%)
Query: 68 SAKPGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGEC 127
+ K G A P G AG + GE+G G P +G + P PGE+G
Sbjct: 610 AGKDGEAGAQGP----PGPAGPAGERGEQGPAGSPGFQG-LPGPAGPPGEAGKPGEQGVP 664
Query: 128 GVPWREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPW 187
G G P RG PGE+G G P G P + + G KG+ G P
Sbjct: 665 GDLGAPG----PSGARGERGFPGERGVQGPPGPAG----PRGANGAPGNDGAKGDAGAPG 716
Query: 188 REGGVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREG- 246
G P G PGE+G G+P +G G KG G P ++G
Sbjct: 717 APGSQGAP----GLQGMPGERGAAGLPGPKG----------DRGDAGPKGADGSPGKDGV 762
Query: 247 -PVWRPLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGGVW 305
+ P+ G +PG+KGE G G P R +PG++GE G P G
Sbjct: 763 RGLTGPIGPPGPAGAPGDKGESGPSGPAG----PTGAR---GAPGDRGEPGPPGPAGFAG 815
Query: 306 RPLERRASVASPGEKGECGVPWREG--------GVWRPLDRRGSVASPGEKGECG 352
P + PG KGE G +G G P G+V +PG KG G
Sbjct: 816 PP----GADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARG 866
Score = 82.4 bits (202), Expect = 6e-16
Identities = 84/297 (28%), Positives = 101/297 (34%), Gaps = 41/297 (13%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
P P P+ + GE G A+G G G P G+ E PG GE G P
Sbjct: 192 PPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGE----AGKPGRPGERGPP 247
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
+G P G+ PG KG G +G + G KGE G P G
Sbjct: 248 GPQGARGLP----GTAGLPGMKGHRGFSGLDGA-------KGDAGPAGPKGEPGSPGENG 296
Query: 191 --GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPV 248
G P G PG G G +G + PG G G P G V
Sbjct: 297 APGQMGPRGLPGERGRPGAPGPAGARGNDGAT-------GAAGPPGPTGPAGPPGFPGAV 349
Query: 249 WR-----PLERRGSVASPGEKGECGVPWTEGGVWRPLERRASVASPGEKGECGVPWTEGG 303
P RGS G +GE G P G P + PG KG G P G
Sbjct: 350 GAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAA-GPAGNPGADGQPGAKGANGAPGIAG- 407
Query: 304 VWRPLERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECGVRWREGRV 360
+ PG +G G P GG P G +PG KG+ G + G V
Sbjct: 408 ---------APGFPGARGPSG-PQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPV 454
Score = 68.2 bits (165), Expect = 1e-11
Identities = 78/284 (27%), Positives = 101/284 (35%), Gaps = 59/284 (20%)
Query: 71 PGSVPAPRPLRSIDGEAGHSEAAGEKGECGIPWTEGQVWRPLERRASVASPGEKGECGVP 130
PG+ P P+ + G G GE+G G+P G+ PG++G G
Sbjct: 946 PGT-PGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGE-------------PGKQGPSGAS 991
Query: 131 WREGRVWRPLDRRGSVASPGEKGECGVPWREGGVWRPLERRASVASPGQKGECGVPWREG 190
G P+ G PGE G G P EG R SPG KG+ G E
Sbjct: 992 GERGPP-GPMGPPGLAGPPGESGREGAPGAEGSPGRD-------GSPGAKGDRG----ET 1039
Query: 191 GVWRPLERRGSVASPGEKGECGVPWREGRVWRPLERRASVASPGQKGECGVPWREGPVWR 250
G P G+ +PG G G + G R G G G GP
Sbjct: 1040 G---PAGPPGAPGAPGAPGPVGPAGKSG-------DRGETGPAGPAGPVGPVGARGPA-G 1088
Query: 251 PLERRGSVASPGEKGECGVPWTEG--GVWRPLERRASVASPGEKGECGVPWTEGGVWRPL 308
P RG GE+G+ G+ G G+ P SPGE+G G G P
Sbjct: 1089 PQGPRGDKGETGEQGDRGIKGHRGFSGLQGP---PGPPGSPGEQGPSGASGPAG----PR 1141
Query: 309 ERRASVASPGEKGECGVPWREGGVWRPLDRRGSVASPGEKGECG 352
S +PG+ G G+P G + PG +G G
Sbjct: 1142 GPPGSAGAPGKDGLNGLP-------------GPIGPPGPRGRTG 1172
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.136 0.455
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,320,045
Number of Sequences: 37866
Number of extensions: 1257198
Number of successful extensions: 11488
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 120
Number of HSP's successfully gapped in prelim test: 251
Number of HSP's that attempted gapping in prelim test: 2864
Number of HSP's gapped (non-prelim): 1938
length of query: 389
length of database: 18,247,518
effective HSP length: 104
effective length of query: 285
effective length of database: 14,309,454
effective search space: 4078194390
effective search space used: 4078194390
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.