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Search of human proteins with 224494026
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224494026 tumor necrosis factor receptor superfamily, member
10b isoform 2 precursor [Homo sapiens]
(411 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224494026 tumor necrosis factor receptor superfamily, member ... 842 0.0
gi|224494019 tumor necrosis factor receptor superfamily, member ... 827 0.0
gi|21361086 tumor necrosis factor receptor superfamily, member 1... 403 e-112
gi|22547108 tumor necrosis factor receptor superfamily, member 1... 288 6e-78
gi|22547121 tumor necrosis factor receptor superfamily, member 1... 149 5e-36
gi|23510423 tumor necrosis factor receptor superfamily, member 6... 67 2e-11
gi|4507583 tumor necrosis factor receptor superfamily, member 6 ... 67 2e-11
gi|23510421 tumor necrosis factor receptor superfamily, member 6... 66 5e-11
gi|23200021 tumor necrosis factor receptor superfamily, member 2... 60 4e-09
gi|4505039 lymphotoxin beta receptor [Homo sapiens] 57 3e-08
gi|4507569 tumor necrosis factor receptor superfamily, member 25... 57 4e-08
gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapi... 55 2e-07
gi|4507577 tumor necrosis factor receptor 2 precursor [Homo sapi... 53 4e-07
gi|23200023 tumor necrosis factor receptor superfamily, member 2... 53 4e-07
gi|23200041 tumor necrosis factor receptor superfamily, member 1... 49 1e-05
gi|23200025 tumor necrosis factor receptor superfamily, member 2... 47 3e-05
gi|7657039 tumor necrosis factor receptor superfamily, member 21... 46 5e-05
gi|4505393 nerve growth factor receptor precursor [Homo sapiens] 46 5e-05
gi|148743793 osteoprotegerin precursor [Homo sapiens] 44 3e-04
gi|4507579 tumor necrosis factor receptor superfamily, member 4 ... 42 0.001
gi|23200031 tumor necrosis factor receptor superfamily, member 2... 42 0.001
gi|68348711 tumor necrosis factor receptor superfamily, member 8... 41 0.002
gi|221316650 ephrin receptor EphA1 [Homo sapiens] 38 0.019
gi|14790170 tumor necrosis factor receptor superfamily, member 6... 37 0.033
gi|4507585 tumor necrosis factor receptor superfamily, member 6b... 37 0.033
gi|4507565 tumor necrosis factor receptor superfamily, member 11... 36 0.073
gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens] 35 0.095
gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens] 35 0.095
gi|145312251 EPH receptor A6 isoform a [Homo sapiens] 35 0.095
gi|4507587 tumor necrosis factor receptor superfamily, member 7 ... 35 0.12
>gi|224494026 tumor necrosis factor receptor superfamily, member 10b
isoform 2 precursor [Homo sapiens]
Length = 411
Score = 842 bits (2176), Expect = 0.0
Identities = 411/411 (100%), Positives = 411/411 (100%)
Query: 1 MEQRGQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLLLVSAESALITQQD 60
MEQRGQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLLLVSAESALITQQD
Sbjct: 1 MEQRGQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLLLVSAESALITQQD 60
Query: 61 LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD 120
LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD
Sbjct: 61 LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD 120
Query: 121 SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH 180
SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH
Sbjct: 121 SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH 180
Query: 181 KESGIIIGVTVAAVVLIVAVFVCKSLLWKKVLPYLKGICSGGGGDPERVDRSSQRPGAED 240
KESGIIIGVTVAAVVLIVAVFVCKSLLWKKVLPYLKGICSGGGGDPERVDRSSQRPGAED
Sbjct: 181 KESGIIIGVTVAAVVLIVAVFVCKSLLWKKVLPYLKGICSGGGGDPERVDRSSQRPGAED 240
Query: 241 NVLNEIVSILQPTQVPEQEMEVQEPAEPTGVNMLSPGESEHLLEPAEAERSQRRRLLVPA 300
NVLNEIVSILQPTQVPEQEMEVQEPAEPTGVNMLSPGESEHLLEPAEAERSQRRRLLVPA
Sbjct: 241 NVLNEIVSILQPTQVPEQEMEVQEPAEPTGVNMLSPGESEHLLEPAEAERSQRRRLLVPA 300
Query: 301 NEGDPTETLRQCFDDFADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKW 360
NEGDPTETLRQCFDDFADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKW
Sbjct: 301 NEGDPTETLRQCFDDFADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKW 360
Query: 361 VNKTGRDASVHTLLDALETLGERLAKQKIEDHLLSSGKFMYLEGNADSAMS 411
VNKTGRDASVHTLLDALETLGERLAKQKIEDHLLSSGKFMYLEGNADSAMS
Sbjct: 361 VNKTGRDASVHTLLDALETLGERLAKQKIEDHLLSSGKFMYLEGNADSAMS 411
>gi|224494019 tumor necrosis factor receptor superfamily, member 10b
isoform 1 precursor [Homo sapiens]
Length = 440
Score = 827 bits (2136), Expect = 0.0
Identities = 411/440 (93%), Positives = 411/440 (93%), Gaps = 29/440 (6%)
Query: 1 MEQRGQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLLLVSAESALITQQD 60
MEQRGQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLLLVSAESALITQQD
Sbjct: 1 MEQRGQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLLLVSAESALITQQD 60
Query: 61 LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD 120
LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD
Sbjct: 61 LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD 120
Query: 121 SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH 180
SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH
Sbjct: 121 SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH 180
Query: 181 KESG-----------------------------IIIGVTVAAVVLIVAVFVCKSLLWKKV 211
KESG IIIGVTVAAVVLIVAVFVCKSLLWKKV
Sbjct: 181 KESGTKHSGEVPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWKKV 240
Query: 212 LPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGV 271
LPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGV
Sbjct: 241 LPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGV 300
Query: 272 NMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRK 331
NMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRK
Sbjct: 301 NMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRK 360
Query: 332 LGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIED 391
LGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIED
Sbjct: 361 LGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIED 420
Query: 392 HLLSSGKFMYLEGNADSAMS 411
HLLSSGKFMYLEGNADSAMS
Sbjct: 421 HLLSSGKFMYLEGNADSAMS 440
>gi|21361086 tumor necrosis factor receptor superfamily, member 10a
[Homo sapiens]
Length = 468
Score = 403 bits (1036), Expect = e-112
Identities = 232/423 (54%), Positives = 271/423 (64%), Gaps = 32/423 (7%)
Query: 5 GQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLL-LVSAESALITQQDLAP 63
GQ+ P+A AR PGPR AR A P RV KT VV VLL +V + +A I D
Sbjct: 60 GQHGPSAR-ARAGRAPGPRPAREASPRLRVHKTFKFVVVGVLLQVVPSSAATIKLHD--- 115
Query: 64 QQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSGE 123
Q QQ SP LCPPG H SE C C G Y+ N+L CL CT C S E
Sbjct: 116 -QSIGTQQWEHSPLGELCPPGSHRSEHPGACNRCTEGVGYTNASNNLFACLPCTACKSDE 174
Query: 124 VELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKES 183
E SPCTTTRNT CQC+ GTFR ++S EMCRKC GCPRGMVKV DCTPWSDIECVHKES
Sbjct: 175 EERSPCTTTRNTACQCKPGTFRNDNSAEMCRKCSRGCPRGMVKVKDCTPWSDIECVHKES 234
Query: 184 G------IIIGVTVAAVVLIVAVFVCKSLLWKKVLPYLKGICSGGGGDPERVDRSS---- 233
G +I+ VT+ +L+VAV + I SG GGDP+ +DR
Sbjct: 235 GNGHNIWVILVVTLVVPLLLVAVLIVCCC-----------IGSGCGGDPKCMDRVCFWRL 283
Query: 234 ---QRPGAEDNVLNEIVSILQP--TQVPEQEMEVQEPAEPTGVNMLSPGESEHLLEPAEA 288
+ PGAEDN NEI+S T V EQ+ME QEPA+ TGV + SPGE++ LL PAEA
Sbjct: 284 GLLRGPGAEDNAHNEILSNADSLSTFVSEQQMESQEPADLTGVTVQSPGEAQCLLGPAEA 343
Query: 289 ERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAG 348
E SQRRRLLVPAN DPTETL FD FA++VPFDSW+ LMR+L L NEI V +A AG
Sbjct: 344 EGSQRRRLLVPANGADPTETLMLFFDKFANIVPFDSWDQLMRQLDLTKNEIDVVRAGTAG 403
Query: 349 HRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIEDHLLSSGKFMYLEGNADS 408
D LY ML+KWVNKTGR+AS+HTLLDALE + ER AK+KI+D L+ SGKF+YLE S
Sbjct: 404 PGDALYAMLMKWVNKTGRNASIHTLLDALERMEERHAKEKIQDLLVDSGKFIYLEDGTGS 463
Query: 409 AMS 411
A+S
Sbjct: 464 AVS 466
>gi|22547108 tumor necrosis factor receptor superfamily, member 10d
precursor [Homo sapiens]
Length = 386
Score = 288 bits (737), Expect = 6e-78
Identities = 169/338 (50%), Positives = 202/338 (59%), Gaps = 35/338 (10%)
Query: 5 GQNAPAASGARKRHGPGPREARGARPGPRVPKTL--VLVVAAVLLLVSAESALITQQDLA 62
GQ+ P AS AR PG R A G RP PK L V+ + AVLL V +SA I +QD
Sbjct: 5 GQSVPTASSARAGRYPGARTASGTRPWLLDPKILKFVVFIVAVLLPVRVDSATIPRQDEV 64
Query: 63 PQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSG 122
PQQ APQQ+R S E CP G H SE C C G DY+ N+L CL CT C SG
Sbjct: 65 PQQTVAPQQQRRSLKEEECPAGSHRSEYTGACNPCTEGVDYTIASNNLPSCLLCTVCKSG 124
Query: 123 EVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKE 182
+ S CTTTR+TVCQCE+G+F++++SPEMCR CRTGCPRGMVKV +CTP SDI+C ++
Sbjct: 125 QTNKSSCTTTRDTVCQCEKGSFQDKNSPEMCRTCRTGCPRGMVKVSNCTPRSDIKCKNES 184
Query: 183 SGIIIGVTVAA-----------------------VVLIVAVFVCKSLLWKKVLPYLKGIC 219
+ G T AA +V+I+AV V KK + YLKGIC
Sbjct: 185 AASSTGKTPAAEETVTTILGMLASPYHYLIIIVVLVIILAVVVVGFSCRKKFISYLKGIC 244
Query: 220 SGGGGDPERVDR--------SSQRPGAEDNVLNEIVS--ILQPTQVPEQEMEVQEPAEPT 269
SGGGG PERV R S+ PGAEDN NE +S LQPTQV EQE++ QE AE T
Sbjct: 245 SGGGGGPERVHRVLFRRRSCPSRVPGAEDNARNETLSNRYLQPTQVSEQEIQGQELAELT 304
Query: 270 GVNMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTE 307
GV + P E + LLE AEAE QRRRLLVP N+ D +
Sbjct: 305 GVTVELPEEPQRLLEQAEAEGCQRRRLLVPVNDADSAD 342
>gi|22547121 tumor necrosis factor receptor superfamily, member 10c
precursor [Homo sapiens]
Length = 259
Score = 149 bits (376), Expect = 5e-36
Identities = 78/151 (51%), Positives = 95/151 (62%), Gaps = 3/151 (1%)
Query: 33 RVPKTL--VLVVAAVLLLVSAESALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHHISED 90
R+PKTL V+V+ AVLL V A SA +Q+ PQQ APQQ+R S CP G H SE
Sbjct: 3 RIPKTLKFVVVIVAVLLPVLAYSATTARQEEVPQQTVAPQQQRHSFKGEECPAGSHRSEH 62
Query: 91 GRDCISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSP 150
C C G DY+ N+ C CT C S + S CT TR+TVCQC+EGTFR E+SP
Sbjct: 63 TGACNPCTEGVDYTNASNNEPSCFPCTVCKSDQKHKSSCTMTRDTVCQCKEGTFRNENSP 122
Query: 151 EMCRKCRTGCPRGMVKVGDCTPWSDIECVHK 181
EMCRKC + CP G V+V +CT W DI+CV +
Sbjct: 123 EMCRKC-SRCPSGEVQVSNCTSWDDIQCVEE 152
>gi|23510423 tumor necrosis factor receptor superfamily, member 6
isoform 3 precursor [Homo sapiens]
Length = 220
Score = 67.4 bits (163), Expect = 2e-11
Identities = 41/113 (36%), Positives = 59/113 (52%), Gaps = 15/113 (13%)
Query: 81 CPPGHH------ISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSG---EVELSPCTT 131
CPPG ++ D DC+ C+ G++Y+ + C RC CD G EVE++ CT
Sbjct: 63 CPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEIN-CTR 121
Query: 132 TRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKESG 184
T+NT C+C+ F E C C T C G++K +CT S+ +C KE G
Sbjct: 122 TQNTKCRCKPNFFCNSTVCEHCDPC-TKCEHGIIK--ECTLTSNTKC--KEEG 169
>gi|4507583 tumor necrosis factor receptor superfamily, member 6
isoform 1 precursor [Homo sapiens]
Length = 335
Score = 67.4 bits (163), Expect = 2e-11
Identities = 41/113 (36%), Positives = 59/113 (52%), Gaps = 15/113 (13%)
Query: 81 CPPGHH------ISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSG---EVELSPCTT 131
CPPG ++ D DC+ C+ G++Y+ + C RC CD G EVE++ CT
Sbjct: 63 CPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEIN-CTR 121
Query: 132 TRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKESG 184
T+NT C+C+ F E C C T C G++K +CT S+ +C KE G
Sbjct: 122 TQNTKCRCKPNFFCNSTVCEHCDPC-TKCEHGIIK--ECTLTSNTKC--KEEG 169
>gi|23510421 tumor necrosis factor receptor superfamily, member 6
isoform 2 precursor [Homo sapiens]
Length = 314
Score = 66.2 bits (160), Expect = 5e-11
Identities = 38/107 (35%), Positives = 56/107 (52%), Gaps = 13/107 (12%)
Query: 81 CPPGHH------ISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSG---EVELSPCTT 131
CPPG ++ D DC+ C+ G++Y+ + C RC CD G EVE++ CT
Sbjct: 63 CPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEIN-CTR 121
Query: 132 TRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIEC 178
T+NT C+C+ F E C C T C G++K +CT S+ +C
Sbjct: 122 TQNTKCRCKPNFFCNSTVCEHCDPC-TKCEHGIIK--ECTLTSNTKC 165
>gi|23200021 tumor necrosis factor receptor superfamily, member 25
isoform 1 precursor [Homo sapiens]
Length = 426
Score = 60.1 bits (144), Expect = 4e-09
Identities = 92/365 (25%), Positives = 133/365 (36%), Gaps = 69/365 (18%)
Query: 81 CPPGHHISEDGRD------CISCKYGQDYSTHWNDL--LFCLRCTRCD--SGEVELSPCT 130
CP GH++ + C+ C QD W + C RC CD + +V L C+
Sbjct: 51 CPAGHYLKAPCTEPCGNSTCLVCP--QDTFLAWENHHNSECARCQACDEQASQVALENCS 108
Query: 131 TTRNTVCQCEEGTFRE-------EDSPEMCRKC----------RTGCPRGMVKVGDCTPW 173
+T C C+ G F E SP C+ C R C R G C P
Sbjct: 109 AVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPG 168
Query: 174 ------SDIECVHKE---SGIIIGVTVAAVVLIVA-----VFVCKSLLWKKVLPYLKGIC 219
+ C +G G +AV L VA VF + LL V+P L G
Sbjct: 169 FYEHGDGCVSCPTPPPSLAGAPWGAVQSAVPLSVAGGRVGVFWVQVLLAGLVVPLLLGAT 228
Query: 220 SGGG------------GDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQ---- 263
D ++ + P + L+ ++L P E+ VQ
Sbjct: 229 LTYTYRHCWPHKPLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGN 288
Query: 264 --EPAEPTGVNMLSPGESEHLLE-PAEAERSQRRRLLVPANE-GDPTETLR---QCFDDF 316
P P L P + + P+ A L P + G P L+ Q +D
Sbjct: 289 SWTPGYPETQEALCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYD-V 347
Query: 317 ADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDA 376
D VP W+ +R LGL + EI+ + E RD Y ML +W + + A + + A
Sbjct: 348 MDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRW--RQQQPAGLGAVYAA 405
Query: 377 LETLG 381
LE +G
Sbjct: 406 LERMG 410
>gi|4505039 lymphotoxin beta receptor [Homo sapiens]
Length = 435
Score = 57.0 bits (136), Expect = 3e-08
Identities = 35/92 (38%), Positives = 46/92 (50%), Gaps = 11/92 (11%)
Query: 81 CPPGHHISEDG---RD--CISCKYGQDYSTHWNDLLFCLRCTRCDS--GEVELSPCTTTR 133
CPPG ++S RD C +C Y+ HWN L C C CD G E++PCT+ R
Sbjct: 62 CPPGTYVSAKCSRIRDTVCATCAENS-YNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKR 120
Query: 134 NTVCQCEEGTFREEDSPEMCRKCR--TGCPRG 163
T C+C+ G F + E C C + CP G
Sbjct: 121 KTQCRCQPGMFCAAWALE-CTHCELLSDCPPG 151
Score = 36.6 bits (83), Expect = 0.043
Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 3/66 (4%)
Query: 116 CTRCDSGEVELSPCTTTRNTVC-QCEEGTFREE-DSPEMCRKCRTGCP-RGMVKVGDCTP 172
C+RC G + C+ R+TVC C E ++ E + +C+ CR P G+ ++ CT
Sbjct: 59 CSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTS 118
Query: 173 WSDIEC 178
+C
Sbjct: 119 KRKTQC 124
>gi|4507569 tumor necrosis factor receptor superfamily, member 25
isoform 2 precursor [Homo sapiens]
Length = 417
Score = 56.6 bits (135), Expect = 4e-08
Identities = 84/356 (23%), Positives = 126/356 (35%), Gaps = 60/356 (16%)
Query: 81 CPPGHHISEDGRD------CISCKYGQDYSTHWNDL--LFCLRCTRCD--SGEVELSPCT 130
CP GH++ + C+ C QD W + C RC CD + +V L C+
Sbjct: 51 CPAGHYLKAPCTEPCGNSTCLVCP--QDTFLAWENHHNSECARCQACDEQASQVALENCS 108
Query: 131 TTRNTVCQCEEGTFRE-------EDSPEMCRKC----------RTGCPRGMVKVGDCTPW 173
+T C C+ G F E SP C+ C R C R G C P
Sbjct: 109 AVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPG 168
Query: 174 -------------SDIECVHKESGIIIGVTVAAVVLIVAVFVCKSLLWKKVLPYLKGICS 220
S + + + G V ++ + LL L Y C
Sbjct: 169 FYEHGDGCVSCPTSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCW 228
Query: 221 GGG----GDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQ------EPAEPTG 270
D ++ + P + L+ ++L P E+ VQ P P
Sbjct: 229 PHKPLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPET 288
Query: 271 VNMLSPGESEHLLE-PAEAERSQRRRLLVPANE-GDPTETLR---QCFDDFADLVPFDSW 325
L P + + P+ A L P + G P L+ Q +D D VP W
Sbjct: 289 QEALCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYD-VMDAVPARRW 347
Query: 326 EPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLG 381
+ +R LGL + EI+ + E RD Y ML +W + + A + + ALE +G
Sbjct: 348 KEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRW--RQQQPAGLGAVYAALERMG 401
>gi|4507575 tumor necrosis factor receptor 1 precursor [Homo
sapiens]
Length = 455
Score = 54.7 bits (130), Expect = 2e-07
Identities = 96/426 (22%), Positives = 155/426 (36%), Gaps = 95/426 (22%)
Query: 34 VPKTLVLVVAAVLLLVSAESALITQQ----DLAPQQRAAPQQKRSSPSEGL-----CPPG 84
VP L+ +V LL+ S +I D + PQ K P C G
Sbjct: 6 VPDLLLPLVLLELLVGIYPSGVIGLVPHLGDREKRDSVCPQGKYIHPQNNSICCTKCHKG 65
Query: 85 HHISED------GRDCISCKYGQDYSTHWNDLLFCLRCTRC--DSGEVELSPCTTTRNTV 136
++ D DC C+ G ++ N L CL C++C + G+VE+S CT R+TV
Sbjct: 66 TYLYNDCPGPGQDTDCRECESGS-FTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTV 124
Query: 137 CQCEEGTFREEDSPEM-----CRKCRTG---------------CPRG-MVKVGDCTPWSD 175
C C + +R S + C C G C G ++ +C S+
Sbjct: 125 CGCRKNQYRHYWSENLFQCFNCSLCLNGTVHLSCQEKQNTVCTCHAGFFLRENECVSCSN 184
Query: 176 ----IEC-------VHKESGIIIGVTVAAVVLIVAVFVC-KSLL----------WKKVLP 213
+EC + G T + L++ +C SLL WK L
Sbjct: 185 CKKSLECTKLCLPQIENVKGTEDSGTTVLLPLVIFFGLCLLSLLFIGLMYRYQRWKSKLY 244
Query: 214 YLKGICSGGGGDPER---VDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTG 270
+ +C G PE+ ++ ++ +P A + + P P + T
Sbjct: 245 SI--VC--GKSTPEKEGELEGTTTKPLAPNPSFSP-----TPGFTPTLGFSPVPSSTFTS 295
Query: 271 VNMLSPGESEHLLEPAEAERSQRR---RLLVPANEGDPTETLRQCFDDFA---------- 317
+ +PG+ + P + +L A DP Q ++D A
Sbjct: 296 SSTYTPGDCPNFAAPRREVAPPYQGADPILATALASDPIPNPLQKWEDSAHKPQSLDTDD 355
Query: 318 --------DLVPFDSWEPLMRKLGLMDNEI-KVAKAEAAGHRDTLYTMLIKWVNKTGRDA 368
+ VP W+ +R+LGL D+EI ++ R+ Y+ML W +T R
Sbjct: 356 PATLYAVVENVPPLRWKEFVRRLGLSDHEIDRLELQNGRCLREAQYSMLATWRRRTPRRE 415
Query: 369 SVHTLL 374
+ LL
Sbjct: 416 ATLELL 421
>gi|4507577 tumor necrosis factor receptor 2 precursor [Homo
sapiens]
Length = 461
Score = 53.1 bits (126), Expect = 4e-07
Identities = 37/110 (33%), Positives = 48/110 (43%), Gaps = 17/110 (15%)
Query: 81 CPPGHHIS-----EDGRDCISCKYGQDYSTHWNDLLFCLRC-TRCDSGEVELSPCTTTRN 134
C PG H C SC+ Y+ WN + CL C +RC S +VE CT +N
Sbjct: 57 CSPGQHAKVFCTKTSDTVCDSCE-DSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQN 115
Query: 135 TVCQCEEGTFREEDSPEMC------RKCRTGCPRGMVKVGDCTPWSDIEC 178
+C C G + E C RKCR G G+ + G T SD+ C
Sbjct: 116 RICTCRPGWYCALSKQEGCRLCAPLRKCRPGF--GVARPG--TETSDVVC 161
Score = 35.4 bits (80), Expect = 0.095
Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 4/59 (6%)
Query: 116 CTRCDSGEVELSPCTTTRNTVC-QCEEGTFRE--EDSPEMCRKCRTGCPRGMVKVGDCT 171
C++C G+ CT T +TVC CE+ T+ + PE C C + C V+ CT
Sbjct: 54 CSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPE-CLSCGSRCSSDQVETQACT 111
>gi|23200023 tumor necrosis factor receptor superfamily, member 25
isoform 3 precursor [Homo sapiens]
Length = 380
Score = 53.1 bits (126), Expect = 4e-07
Identities = 79/339 (23%), Positives = 121/339 (35%), Gaps = 63/339 (18%)
Query: 81 CPPGHHISEDGRD------CISCKYGQDYSTHWNDL--LFCLRCTRCD--SGEVELSPCT 130
CP GH++ + C+ C QD W + C RC CD + +V L C+
Sbjct: 51 CPAGHYLKAPCTEPCGNSTCLVCP--QDTFLAWENHHNSECARCQACDEQASQVALENCS 108
Query: 131 TTRNTVCQCEEGTFRE-------EDSPEMCRKC----------RTGCPRGMVKVGDCTPW 173
+T C C+ G F E SP C+ C R C R G C P
Sbjct: 109 AVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPG 168
Query: 174 SDIECVHKESGIIIGVTVAAVVLIVAVFVCKSLLWKKVLPYLKGICSGGGGDPERVDRSS 233
H + + + VC W++ + ++ +
Sbjct: 169 F---YEHGDGCVSCPTSTLGSCPERCAAVCG---WRQ--------------NEAGMEALT 208
Query: 234 QRPGAEDNVLNEIVSILQPTQVPEQEMEVQ------EPAEPTGVNMLSPGESEHLLE-PA 286
P + L+ ++L P E+ VQ P P L P + + P+
Sbjct: 209 PPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSWDQLPS 268
Query: 287 EAERSQRRRLLVPANE-GDPTETLR---QCFDDFADLVPFDSWEPLMRKLGLMDNEIKVA 342
A L P + G P L+ Q +D D VP W+ +R LGL + EI+
Sbjct: 269 RALGPAAAPTLSPESPAGSPAMMLQPGPQLYD-VMDAVPARRWKEFVRTLGLREAEIEAV 327
Query: 343 KAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLG 381
+ E RD Y ML +W + + A + + ALE +G
Sbjct: 328 EVEIGRFRDQQYEMLKRW--RQQQPAGLGAVYAALERMG 364
>gi|23200041 tumor necrosis factor receptor superfamily, member 14
precursor [Homo sapiens]
Length = 283
Score = 48.5 bits (114), Expect = 1e-05
Identities = 46/154 (29%), Positives = 58/154 (37%), Gaps = 20/154 (12%)
Query: 27 GARPGPRVPKTLVLVVAAVLLLVSAESALITQQDLAPQQRAAPQQKRSSPSEGL--CPPG 84
G P PKT VL + L + A AP + + + SE C PG
Sbjct: 8 GPPPWRSTPKTDVLRLVLYLTFLGAPC-------YAPALPSCKEDEYPVGSECCPKCSPG 60
Query: 85 HHISE-----DGRDCISCKYGQDYSTHWNDLLFCLRCTRCDS--GEVELSPCTTTRNTVC 137
+ + E G C C G Y H N L CL+C CD G C+ T N VC
Sbjct: 61 YRVKEACGELTGTVCEPCPPGT-YIAHLNGLSKCLQCQMCDPAMGLRASRNCSRTENAVC 119
Query: 138 QCEEGTF---REEDSPEMCRKCRTGCPRGMVKVG 168
C G F ++ D CR T P V+ G
Sbjct: 120 GCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKG 153
>gi|23200025 tumor necrosis factor receptor superfamily, member 25
isoform 4 precursor [Homo sapiens]
Length = 372
Score = 47.0 bits (110), Expect = 3e-05
Identities = 75/317 (23%), Positives = 112/317 (35%), Gaps = 51/317 (16%)
Query: 111 LFCLRCTRCDSG-EVELSPCTTTRNTVCQCEEGTFRE-------EDSPEMCRKC------ 156
LFC C C + +V L C+ +T C C+ G F E SP C+ C
Sbjct: 45 LFC--CRGCPAASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGAL 102
Query: 157 ----RTGCPRGMVKVGDCTPW-------------SDIECVHKESGIIIGVTVAAVVLIVA 199
R C R G C P S + + + G V ++
Sbjct: 103 HRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTSTLGSCPERCAAVCGWRQMFWVQVLL 162
Query: 200 VFVCKSLLWKKVLPYLKGICSGGG----GDPERVDRSSQRPGAEDNVLNEIVSILQPTQV 255
+ LL L Y C D ++ + P + L+ ++L P
Sbjct: 163 AGLVVPLLLGATLTYTYRHCWPHKPLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDS 222
Query: 256 PEQEMEVQ------EPAEPTGVNMLSPGESEHLLE-PAEAERSQRRRLLVPANE-GDPTE 307
E+ VQ P P L P + + P+ A L P + G P
Sbjct: 223 SEKICTVQLVGNSWTPGYPETQEALCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAM 282
Query: 308 TLR---QCFDDFADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKT 364
L+ Q +D D VP W+ +R LGL + EI+ + E RD Y ML +W +
Sbjct: 283 MLQPGPQLYD-VMDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRW--RQ 339
Query: 365 GRDASVHTLLDALETLG 381
+ A + + ALE +G
Sbjct: 340 QQPAGLGAVYAALERMG 356
>gi|7657039 tumor necrosis factor receptor superfamily, member 21
precursor [Homo sapiens]
Length = 655
Score = 46.2 bits (108), Expect = 5e-05
Identities = 25/67 (37%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Query: 114 LRCTRCDSGEVELSPCTTTRNTVCQ-CEEGTF-REEDSPEMCRKCRTGCPRGMVKVGDCT 171
L C +C +G CT T VC C GTF R E+ E C C CP M++ C
Sbjct: 65 LTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKLPCA 124
Query: 172 PWSDIEC 178
+D EC
Sbjct: 125 ALTDREC 131
Score = 39.3 bits (90), Expect = 0.007
Identities = 44/163 (26%), Positives = 61/163 (37%), Gaps = 12/163 (7%)
Query: 81 CPPGHHISEDG-----RDCISCKYGQDYSTHWNDLLFCLRCTR-CDSGEVELSPCTTTRN 134
CP G ++SE R C SC G ++ H N + C C++ C +E PC +
Sbjct: 70 CPAGTYVSEHCTNTSLRVCSSCPVGT-FTRHENGIEKCHDCSQPCPWPMIEKLPCAALTD 128
Query: 135 TVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKESGIIIGVTVAAV 194
C C G F+ S C T CP G T D+ C G V ++V
Sbjct: 129 RECTCPPGMFQ---SNATCAP-HTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVP-SSV 183
Query: 195 VLIVAVFVCKSLLWKKVLPYLKGICSGGGGDPERVDRSSQRPG 237
+ A C S + P K + G P +S PG
Sbjct: 184 MKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSSTSPSPG 226
>gi|4505393 nerve growth factor receptor precursor [Homo sapiens]
Length = 427
Score = 46.2 bits (108), Expect = 5e-05
Identities = 29/86 (33%), Positives = 44/86 (51%), Gaps = 10/86 (11%)
Query: 97 CKYG--QDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVC-QCEEGTFREE-DSPEM 152
C YG QD +T C C C++G + C +NTVC +C +GT+ +E + +
Sbjct: 109 CAYGYYQDETTGR-----CEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDP 163
Query: 153 CRKCRTGCPRGMVKVGDCTPWSDIEC 178
C C T C ++ +CT W+D EC
Sbjct: 164 CLPC-TVCEDTERQLRECTRWADAEC 188
Score = 30.8 bits (68), Expect = 2.3
Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 1/57 (1%)
Query: 94 CISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSP 150
C C G YS N + CL CT C+ E +L CT + C+ G + +P
Sbjct: 146 CEECPDGT-YSDEANHVDPCLPCTVCEDTERQLRECTRWADAECEEIPGRWITRSTP 201
>gi|148743793 osteoprotegerin precursor [Homo sapiens]
Length = 401
Score = 43.9 bits (102), Expect = 3e-04
Identities = 34/116 (29%), Positives = 46/116 (39%), Gaps = 11/116 (9%)
Query: 81 CPPGHHISEDGRD-----CISCKYGQDYSTHWNDLLFCLRCTR-CDSGEVELSPCTTTRN 134
CPPG ++ + C C Y+ W+ CL C+ C + C T N
Sbjct: 44 CPPGTYLKQHCTAKWKTVCAPCP-DHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHN 102
Query: 135 TVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKESGIIIGVT 190
VC+C+EG + E E C K R+ CP G V TP + C G T
Sbjct: 103 RVCECKEGRYLE---IEFCLKHRS-CPPGFGVVQAGTPERNTVCKRCPDGFFSNET 154
>gi|4507579 tumor necrosis factor receptor superfamily, member 4
precursor [Homo sapiens]
Length = 277
Score = 41.6 bits (96), Expect = 0.001
Identities = 27/76 (35%), Positives = 36/76 (47%), Gaps = 7/76 (9%)
Query: 113 CLRCTRCD--SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGD- 169
C CT C+ SG CT T++TVC+C GT + DS + C CP G GD
Sbjct: 81 CKPCTWCNLRSGSERKQLCTATQDTVCRCRAGT-QPLDSYKPGVDC-APCPPGHFSPGDN 138
Query: 170 --CTPWSDIECVHKES 183
C PW++ K +
Sbjct: 139 QACKPWTNCTLAGKHT 154
Score = 34.7 bits (78), Expect = 0.16
Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 10/69 (14%)
Query: 116 CTRCDSGEVELSPCTTTRNTVCQ-CEEGTFREEDSPEMCRKC-----RTGCPRGMVKVGD 169
C C G +S C+ ++NTVC+ C G + + S + C+ C R+G R +
Sbjct: 43 CHECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGSERKQL---- 98
Query: 170 CTPWSDIEC 178
CT D C
Sbjct: 99 CTATQDTVC 107
>gi|23200031 tumor necrosis factor receptor superfamily, member 25
isoform 7 precursor [Homo sapiens]
Length = 234
Score = 41.6 bits (96), Expect = 0.001
Identities = 23/67 (34%), Positives = 34/67 (50%), Gaps = 2/67 (2%)
Query: 315 DFADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLL 374
D D VP W+ +R LGL + EI+ + E RD Y ML +W + + A + +
Sbjct: 154 DVMDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRW--RQQQPAGLGAVY 211
Query: 375 DALETLG 381
ALE +G
Sbjct: 212 AALERMG 218
>gi|68348711 tumor necrosis factor receptor superfamily, member 8
isoform 1 precursor [Homo sapiens]
Length = 595
Score = 41.2 bits (95), Expect = 0.002
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 4/75 (5%)
Query: 113 CLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKC--RTGCPRGMVKVGDC 170
C+ C+R D VE +PC + VC+C G F + C +C + CP GM+
Sbjct: 84 CVTCSRDDL--VEKTPCAWNSSRVCECRPGMFCSTSAVNSCARCFFHSVCPAGMIVKFPG 141
Query: 171 TPWSDIECVHKESGI 185
T + C G+
Sbjct: 142 TAQKNTVCEPASPGV 156
Score = 29.6 bits (65), Expect = 5.2
Identities = 30/138 (21%), Positives = 44/138 (31%), Gaps = 11/138 (7%)
Query: 8 APAASGARKRHGPGPREARGARPGPRVPKTL---VLVVAAVLLLVSAESALITQQDLAPQ 64
+PA + P A+P P P T + V L ++ +T+ +P
Sbjct: 157 SPACASPENCKEPSSGTIPQAKPTPVSPATSSASTMPVRGGTRLAQEAASKLTRAPDSPS 216
Query: 65 QRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSGEV 124
P CP G DC Y C+ C+R D V
Sbjct: 217 SVGRPSSDPGLSPTQPCPEG------SGDCRKQCEPDYYLDEAGRCTACVSCSRDDL--V 268
Query: 125 ELSPCTTTRNTVCQCEEG 142
E +PC + C+C G
Sbjct: 269 EKTPCAWNSSRTCECRPG 286
Score = 28.9 bits (63), Expect = 8.9
Identities = 17/51 (33%), Positives = 25/51 (49%), Gaps = 4/51 (7%)
Query: 113 CLRC---TRCDSGEVELSPCTTTRNTVCQ-CEEGTFREEDSPEMCRKCRTG 159
C RC + C +G + P T +NTVC+ G SPE C++ +G
Sbjct: 122 CARCFFHSVCPAGMIVKFPGTAQKNTVCEPASPGVSPACASPENCKEPSSG 172
>gi|221316650 ephrin receptor EphA1 [Homo sapiens]
Length = 976
Score = 37.7 bits (86), Expect = 0.019
Identities = 31/125 (24%), Positives = 47/125 (37%), Gaps = 17/125 (13%)
Query: 48 LVSAESALITQQDLAPQQRAAPQQKRSSPSEGL-------CPPGHHISEDGRDCISCKYG 100
LV + +P+ AP+ S E L C PG+ G C++C G
Sbjct: 224 LVEVAGTCLPHARASPRPSGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSG 283
Query: 101 QDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREE-DSPEMCRKCRTG 159
Y D CL C + + E E + T+C CE G +R + P++
Sbjct: 284 -SYRMDM-DTPHCLTCPQQSTAESEGA-------TICTCESGHYRAPGEGPQVACTGPPS 334
Query: 160 CPRGM 164
PR +
Sbjct: 335 APRNL 339
>gi|14790170 tumor necrosis factor receptor superfamily, member 6b
[Homo sapiens]
Length = 300
Score = 37.0 bits (84), Expect = 0.033
Identities = 33/120 (27%), Positives = 46/120 (38%), Gaps = 30/120 (25%)
Query: 72 KRSSPSE-GLCPPGHHIS-------------------EDGRDCIS-----CKYGQDYSTH 106
+R SP+ G CPP H+ E+ R C + C+ + H
Sbjct: 63 RRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAH 122
Query: 107 WNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQ-CEEGTF-REEDSPEMCRKCRTGCPRGM 164
FCL C G ++P T ++NT CQ C GTF S E C+ R G+
Sbjct: 123 AG---FCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGL 179
>gi|4507585 tumor necrosis factor receptor superfamily, member 6b
[Homo sapiens]
Length = 300
Score = 37.0 bits (84), Expect = 0.033
Identities = 33/120 (27%), Positives = 46/120 (38%), Gaps = 30/120 (25%)
Query: 72 KRSSPSE-GLCPPGHHIS-------------------EDGRDCIS-----CKYGQDYSTH 106
+R SP+ G CPP H+ E+ R C + C+ + H
Sbjct: 63 RRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAH 122
Query: 107 WNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQ-CEEGTF-REEDSPEMCRKCRTGCPRGM 164
FCL C G ++P T ++NT CQ C GTF S E C+ R G+
Sbjct: 123 AG---FCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGL 179
>gi|4507565 tumor necrosis factor receptor superfamily, member 11a
precursor [Homo sapiens]
Length = 616
Score = 35.8 bits (81), Expect = 0.073
Identities = 33/119 (27%), Positives = 49/119 (41%), Gaps = 19/119 (15%)
Query: 106 HWNDLLFCLRCTRCDSGEVELSPCTTTRNTVC-QCEE----GTFREEDSPEMCRKCRTGC 160
H+ L C C +C+ G+ S CTTT ++VC C ++ EED + + C TG
Sbjct: 39 HYEHLGRC--CNKCEPGKYMSSKCTTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGK 96
Query: 161 PRGMVKVGDCTP-----------WS-DIECVHKESGIIIGVTVAAVVLIVAVFVCKSLL 207
V G+ T WS D EC + + G+ + + VCK L
Sbjct: 97 ALVAVVAGNSTTPRRCACTAGYHWSQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCL 155
Score = 33.9 bits (76), Expect = 0.28
Identities = 34/127 (26%), Positives = 51/127 (40%), Gaps = 8/127 (6%)
Query: 44 AVLLLVSAESALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHHISED---GRDCISCKYG 100
A+LLL + + L +AP + + C PG ++S D + G
Sbjct: 13 ALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKCTTTSDSVCLPCG 72
Query: 101 QD-YSTHWNDLLFCLRCTRCDSGE--VELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCR 157
D Y WN+ CL CD+G+ V + +T C C G +D E CR+
Sbjct: 73 PDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHWSQDC-ECCRR-N 130
Query: 158 TGCPRGM 164
T C G+
Sbjct: 131 TECAPGL 137
>gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]
Length = 277
Score = 35.4 bits (80), Expect = 0.095
Identities = 30/110 (27%), Positives = 45/110 (40%), Gaps = 14/110 (12%)
Query: 63 PQQRAAPQQKR---SSPSEGLCPPGHHISED-----GRDCISCKYGQDYSTHWNDLLFCL 114
P+ A ++K+ +S LC PG + D +C+ C + T WN C
Sbjct: 20 PEPPTACREKQYLINSQCCSLCQPGQKLVSDCTEFTETECLPCGESEFLDT-WNRETHCH 78
Query: 115 RCTRCDS--GEVELSPCTTTRNTVCQCEEGTFREEDSPEMC---RKCRTG 159
+ CD G T+ +T+C CEEG ++ E C R C G
Sbjct: 79 QHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCTSEACESCVLHRSCSPG 128
>gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]
Length = 203
Score = 35.4 bits (80), Expect = 0.095
Identities = 30/110 (27%), Positives = 45/110 (40%), Gaps = 14/110 (12%)
Query: 63 PQQRAAPQQKR---SSPSEGLCPPGHHISED-----GRDCISCKYGQDYSTHWNDLLFCL 114
P+ A ++K+ +S LC PG + D +C+ C + T WN C
Sbjct: 20 PEPPTACREKQYLINSQCCSLCQPGQKLVSDCTEFTETECLPCGESEFLDT-WNRETHCH 78
Query: 115 RCTRCDS--GEVELSPCTTTRNTVCQCEEGTFREEDSPEMC---RKCRTG 159
+ CD G T+ +T+C CEEG ++ E C R C G
Sbjct: 79 QHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCTSEACESCVLHRSCSPG 128
>gi|145312251 EPH receptor A6 isoform a [Homo sapiens]
Length = 1130
Score = 35.4 bits (80), Expect = 0.095
Identities = 29/108 (26%), Positives = 46/108 (42%), Gaps = 15/108 (13%)
Query: 64 QQRAAPQQKRSSPSEGLCPPGHHISEDGRD-----CISCKYGQDYSTHWNDLLFCLRCTR 118
++R P+ + + L P G I G + C +C+ G + N +C++
Sbjct: 335 EERDTPKLYCGADGDWLVPLGRCICSTGYEEIEGSCHACRPGFYKAFAGNT-----KCSK 389
Query: 119 CDSGEVELSPCTTTRNTVCQCEEGTFR-EEDSPEMCRKCRTGCPRGMV 165
C + T+ VCQCE+G FR E+D P M PR +V
Sbjct: 390 CPPHSLTYMEATS----VCQCEKGYFRAEKDPPSMACTRPPSAPRNVV 433
>gi|4507587 tumor necrosis factor receptor superfamily, member 7
precursor [Homo sapiens]
Length = 260
Score = 35.0 bits (79), Expect = 0.12
Identities = 20/69 (28%), Positives = 28/69 (40%), Gaps = 7/69 (10%)
Query: 80 LCPPGHHISED------GRDCISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTR 133
+C PG + +D C C G +S + C C C+SG + + CT T
Sbjct: 42 MCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCNSGLL-VRNCTITA 100
Query: 134 NTVCQCEEG 142
N C C G
Sbjct: 101 NAECACRNG 109
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,727,722
Number of Sequences: 37866
Number of extensions: 975746
Number of successful extensions: 4026
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 73
Number of HSP's that attempted gapping in prelim test: 3854
Number of HSP's gapped (non-prelim): 218
length of query: 411
length of database: 18,247,518
effective HSP length: 105
effective length of query: 306
effective length of database: 14,271,588
effective search space: 4367105928
effective search space used: 4367105928
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.