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Search of human proteins with 224494019
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224494019 tumor necrosis factor receptor superfamily, member
10b isoform 1 precursor [Homo sapiens]
(440 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224494019 tumor necrosis factor receptor superfamily, member ... 900 0.0
gi|224494026 tumor necrosis factor receptor superfamily, member ... 827 0.0
gi|21361086 tumor necrosis factor receptor superfamily, member 1... 398 e-111
gi|22547108 tumor necrosis factor receptor superfamily, member 1... 313 3e-85
gi|22547121 tumor necrosis factor receptor superfamily, member 1... 172 7e-43
gi|23510421 tumor necrosis factor receptor superfamily, member 6... 70 3e-12
gi|23510423 tumor necrosis factor receptor superfamily, member 6... 69 1e-11
gi|4507583 tumor necrosis factor receptor superfamily, member 6 ... 69 1e-11
gi|23200021 tumor necrosis factor receptor superfamily, member 2... 64 2e-10
gi|4507569 tumor necrosis factor receptor superfamily, member 25... 64 2e-10
gi|4505039 lymphotoxin beta receptor [Homo sapiens] 62 1e-09
gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapi... 59 9e-09
gi|23200025 tumor necrosis factor receptor superfamily, member 2... 55 2e-07
gi|4507577 tumor necrosis factor receptor 2 precursor [Homo sapi... 54 3e-07
gi|23200041 tumor necrosis factor receptor superfamily, member 1... 50 4e-06
gi|4505393 nerve growth factor receptor precursor [Homo sapiens] 50 5e-06
gi|148743793 osteoprotegerin precursor [Homo sapiens] 47 3e-05
gi|7657039 tumor necrosis factor receptor superfamily, member 21... 46 6e-05
gi|68348711 tumor necrosis factor receptor superfamily, member 8... 44 3e-04
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 42 8e-04
gi|4507579 tumor necrosis factor receptor superfamily, member 4 ... 42 8e-04
gi|23200031 tumor necrosis factor receptor superfamily, member 2... 42 0.001
gi|23200023 tumor necrosis factor receptor superfamily, member 2... 42 0.001
gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens] 41 0.002
gi|14790170 tumor necrosis factor receptor superfamily, member 6... 38 0.016
gi|4507565 tumor necrosis factor receptor superfamily, member 11... 38 0.016
gi|4507585 tumor necrosis factor receptor superfamily, member 6b... 38 0.016
gi|221316650 ephrin receptor EphA1 [Homo sapiens] 38 0.021
gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens] 35 0.10
gi|145312251 EPH receptor A6 isoform a [Homo sapiens] 35 0.10
>gi|224494019 tumor necrosis factor receptor superfamily, member 10b
isoform 1 precursor [Homo sapiens]
Length = 440
Score = 900 bits (2327), Expect = 0.0
Identities = 440/440 (100%), Positives = 440/440 (100%)
Query: 1 MEQRGQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLLLVSAESALITQQD 60
MEQRGQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLLLVSAESALITQQD
Sbjct: 1 MEQRGQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLLLVSAESALITQQD 60
Query: 61 LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD 120
LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD
Sbjct: 61 LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD 120
Query: 121 SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH 180
SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH
Sbjct: 121 SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH 180
Query: 181 KESGTKHSGEVPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWKKV 240
KESGTKHSGEVPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWKKV
Sbjct: 181 KESGTKHSGEVPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWKKV 240
Query: 241 LPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGV 300
LPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGV
Sbjct: 241 LPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGV 300
Query: 301 NMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRK 360
NMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRK
Sbjct: 301 NMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRK 360
Query: 361 LGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIED 420
LGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIED
Sbjct: 361 LGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIED 420
Query: 421 HLLSSGKFMYLEGNADSAMS 440
HLLSSGKFMYLEGNADSAMS
Sbjct: 421 HLLSSGKFMYLEGNADSAMS 440
>gi|224494026 tumor necrosis factor receptor superfamily, member 10b
isoform 2 precursor [Homo sapiens]
Length = 411
Score = 827 bits (2136), Expect = 0.0
Identities = 411/440 (93%), Positives = 411/440 (93%), Gaps = 29/440 (6%)
Query: 1 MEQRGQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLLLVSAESALITQQD 60
MEQRGQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLLLVSAESALITQQD
Sbjct: 1 MEQRGQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLLLVSAESALITQQD 60
Query: 61 LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD 120
LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD
Sbjct: 61 LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD 120
Query: 121 SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH 180
SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH
Sbjct: 121 SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH 180
Query: 181 KESGTKHSGEVPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWKKV 240
KESG IIIGVTVAAVVLIVAVFVCKSLLWKKV
Sbjct: 181 KESG-----------------------------IIIGVTVAAVVLIVAVFVCKSLLWKKV 211
Query: 241 LPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGV 300
LPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGV
Sbjct: 212 LPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGV 271
Query: 301 NMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRK 360
NMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRK
Sbjct: 272 NMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRK 331
Query: 361 LGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIED 420
LGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIED
Sbjct: 332 LGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIED 391
Query: 421 HLLSSGKFMYLEGNADSAMS 440
HLLSSGKFMYLEGNADSAMS
Sbjct: 392 HLLSSGKFMYLEGNADSAMS 411
>gi|21361086 tumor necrosis factor receptor superfamily, member 10a
[Homo sapiens]
Length = 468
Score = 398 bits (1022), Expect = e-111
Identities = 233/446 (52%), Positives = 273/446 (61%), Gaps = 49/446 (10%)
Query: 5 GQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLL-LVSAESALITQQDLAP 63
GQ+ P+A AR PGPR AR A P RV KT VV VLL +V + +A I D
Sbjct: 60 GQHGPSAR-ARAGRAPGPRPAREASPRLRVHKTFKFVVVGVLLQVVPSSAATIKLHD--- 115
Query: 64 QQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSGE 123
Q QQ SP LCPPG H SE C C G Y+ N+L CL CT C S E
Sbjct: 116 -QSIGTQQWEHSPLGELCPPGSHRSEHPGACNRCTEGVGYTNASNNLFACLPCTACKSDE 174
Query: 124 VELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKES 183
E SPCTTTRNT CQC+ GTFR ++S EMCRKC GCPRGMVKV DCTPWSDIECVHKES
Sbjct: 175 EERSPCTTTRNTACQCKPGTFRNDNSAEMCRKCSRGCPRGMVKVKDCTPWSDIECVHKES 234
Query: 184 GTKHSGEVPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWKKVLPY 243
G H+ +I+ VT+ +L+VAV +
Sbjct: 235 GNGHN-----------------------IWVILVVTLVVPLLLVAVLIVCCC-------- 263
Query: 244 LKGICSGGGGDPERVDRSS-------QRPGAEDNVLNEIVSILQP--TQVPEQEMEVQEP 294
I SG GGDP+ +DR + PGAEDN NEI+S T V EQ+ME QEP
Sbjct: 264 ---IGSGCGGDPKCMDRVCFWRLGLLRGPGAEDNAHNEILSNADSLSTFVSEQQMESQEP 320
Query: 295 AEPTGVNMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSW 354
A+ TGV + SPGE++ LL PAEAE SQRRRLLVPAN DPTETL FD FA++VPFDSW
Sbjct: 321 ADLTGVTVQSPGEAQCLLGPAEAEGSQRRRLLVPANGADPTETLMLFFDKFANIVPFDSW 380
Query: 355 EPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLA 414
+ LMR+L L NEI V +A AG D LY ML+KWVNKTGR+AS+HTLLDALE + ER A
Sbjct: 381 DQLMRQLDLTKNEIDVVRAGTAGPGDALYAMLMKWVNKTGRNASIHTLLDALERMEERHA 440
Query: 415 KQKIEDHLLSSGKFMYLEGNADSAMS 440
K+KI+D L+ SGKF+YLE SA+S
Sbjct: 441 KEKIQDLLVDSGKFIYLEDGTGSAVS 466
>gi|22547108 tumor necrosis factor receptor superfamily, member 10d
precursor [Homo sapiens]
Length = 386
Score = 313 bits (801), Expect = 3e-85
Identities = 182/344 (52%), Positives = 216/344 (62%), Gaps = 18/344 (5%)
Query: 5 GQNAPAASGARKRHGPGPREARGARPGPRVPKTL--VLVVAAVLLLVSAESALITQQDLA 62
GQ+ P AS AR PG R A G RP PK L V+ + AVLL V +SA I +QD
Sbjct: 5 GQSVPTASSARAGRYPGARTASGTRPWLLDPKILKFVVFIVAVLLPVRVDSATIPRQDEV 64
Query: 63 PQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSG 122
PQQ APQQ+R S E CP G H SE C C G DY+ N+L CL CT C SG
Sbjct: 65 PQQTVAPQQQRRSLKEEECPAGSHRSEYTGACNPCTEGVDYTIASNNLPSCLLCTVCKSG 124
Query: 123 EVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKE 182
+ S CTTTR+TVCQCE+G+F++++SPEMCR CRTGCPRGMVKV +CTP SDI+C E
Sbjct: 125 QTNKSSCTTTRDTVCQCEKGSFQDKNSPEMCRTCRTGCPRGMVKVSNCTPRSDIKC-KNE 183
Query: 183 SGTKHSGEVPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWKKVLP 242
S +G+ PA EETVT+ G ASP III V V + ++V F C+ KK +
Sbjct: 184 SAASSTGKTPAAEETVTTILGMLASPYHYL-IIIVVLVIILAVVVVGFSCR----KKFIS 238
Query: 243 YLKGICSGGGGDPERVDR--------SSQRPGAEDNVLNEIVS--ILQPTQVPEQEMEVQ 292
YLKGICSGGGG PERV R S+ PGAEDN NE +S LQPTQV EQE++ Q
Sbjct: 239 YLKGICSGGGGGPERVHRVLFRRRSCPSRVPGAEDNARNETLSNRYLQPTQVSEQEIQGQ 298
Query: 293 EPAEPTGVNMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTE 336
E AE TGV + P E + LLE AEAE QRRRLLVP N+ D +
Sbjct: 299 ELAELTGVTVELPEEPQRLLEQAEAEGCQRRRLLVPVNDADSAD 342
>gi|22547121 tumor necrosis factor receptor superfamily, member 10c
precursor [Homo sapiens]
Length = 259
Score = 172 bits (435), Expect = 7e-43
Identities = 92/176 (52%), Positives = 112/176 (63%), Gaps = 4/176 (2%)
Query: 33 RVPKTL--VLVVAAVLLLVSAESALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHHISED 90
R+PKTL V+V+ AVLL V A SA +Q+ PQQ APQQ+R S CP G H SE
Sbjct: 3 RIPKTLKFVVVIVAVLLPVLAYSATTARQEEVPQQTVAPQQQRHSFKGEECPAGSHRSEH 62
Query: 91 GRDCISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSP 150
C C G DY+ N+ C CT C S + S CT TR+TVCQC+EGTFR E+SP
Sbjct: 63 TGACNPCTEGVDYTNASNNEPSCFPCTVCKSDQKHKSSCTMTRDTVCQCKEGTFRNENSP 122
Query: 151 EMCRKCRTGCPRGMVKVGDCTPWSDIECVHKESGTKHSGEVPAVEETVTSSPGTPA 206
EMCRKC + CP G V+V +CT W DI+CV +E G + E PA EET+ +SPGTPA
Sbjct: 123 EMCRKC-SRCPSGEVQVSNCTSWDDIQCV-EEFGANATVETPAAEETMNTSPGTPA 176
>gi|23510421 tumor necrosis factor receptor superfamily, member 6
isoform 2 precursor [Homo sapiens]
Length = 314
Score = 70.5 bits (171), Expect = 3e-12
Identities = 54/168 (32%), Positives = 80/168 (47%), Gaps = 25/168 (14%)
Query: 81 CPPGHH------ISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSG---EVELSPCTT 131
CPPG ++ D DC+ C+ G++Y+ + C RC CD G EVE++ CT
Sbjct: 63 CPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEIN-CTR 121
Query: 132 TRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH-------KESG 184
T+NT C+C+ F E C C T C G++K +CT S+ +C +++
Sbjct: 122 TQNTKCRCKPNFFCNSTVCEHCDPC-TKCEHGIIK--ECTLTSNTKCKEEVKRKEVQKTC 178
Query: 185 TKHSGEVPAVEETVTSSPGTPA---SPCSLSGIIIGVTVAAVVLIVAV 229
KH E E+ T +P T A S LS I T+A V+ + V
Sbjct: 179 RKHRKENQGSHESPTLNPETVAINLSDVDLSKYI--TTIAGVMTLSQV 224
>gi|23510423 tumor necrosis factor receptor superfamily, member 6
isoform 3 precursor [Homo sapiens]
Length = 220
Score = 68.6 bits (166), Expect = 1e-11
Identities = 41/115 (35%), Positives = 61/115 (53%), Gaps = 15/115 (13%)
Query: 81 CPPGHH------ISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSG---EVELSPCTT 131
CPPG ++ D DC+ C+ G++Y+ + C RC CD G EVE++ CT
Sbjct: 63 CPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEIN-CTR 121
Query: 132 TRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKESGTK 186
T+NT C+C+ F E C C T C G++K +CT S+ +C KE G++
Sbjct: 122 TQNTKCRCKPNFFCNSTVCEHCDPC-TKCEHGIIK--ECTLTSNTKC--KEEGSR 171
>gi|4507583 tumor necrosis factor receptor superfamily, member 6
isoform 1 precursor [Homo sapiens]
Length = 335
Score = 68.6 bits (166), Expect = 1e-11
Identities = 41/115 (35%), Positives = 61/115 (53%), Gaps = 15/115 (13%)
Query: 81 CPPGHH------ISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSG---EVELSPCTT 131
CPPG ++ D DC+ C+ G++Y+ + C RC CD G EVE++ CT
Sbjct: 63 CPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEIN-CTR 121
Query: 132 TRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKESGTK 186
T+NT C+C+ F E C C T C G++K +CT S+ +C KE G++
Sbjct: 122 TQNTKCRCKPNFFCNSTVCEHCDPC-TKCEHGIIK--ECTLTSNTKC--KEEGSR 171
>gi|23200021 tumor necrosis factor receptor superfamily, member 25
isoform 1 precursor [Homo sapiens]
Length = 426
Score = 64.3 bits (155), Expect = 2e-10
Identities = 94/375 (25%), Positives = 140/375 (37%), Gaps = 60/375 (16%)
Query: 81 CPPGHHISEDGRD------CISCKYGQDYSTHWNDL--LFCLRCTRCD--SGEVELSPCT 130
CP GH++ + C+ C QD W + C RC CD + +V L C+
Sbjct: 51 CPAGHYLKAPCTEPCGNSTCLVCP--QDTFLAWENHHNSECARCQACDEQASQVALENCS 108
Query: 131 TTRNTVCQCEEGTFRE-------EDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKES 183
+T C C+ G F E SP C+ C + G + + C ++
Sbjct: 109 AVADTRCGCKPGWFVECQVSQCVSSSPFYCQPC--------LDCGALHRHTRLLCSRRD- 159
Query: 184 GTKHSGEVPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVA-----VFVCKSLLWK 238
T +P E P P SL+G G +AV L VA VF + LL
Sbjct: 160 -TDCGTCLPGFYEHGDGCVSCPTPPPSLAGAPWGAVQSAVPLSVAGGRVGVFWVQVLLAG 218
Query: 239 KVLPYLKGICSGGG------------GDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPE 286
V+P L G D ++ + P + L+ ++L P E
Sbjct: 219 LVVPLLLGATLTYTYRHCWPHKPLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSE 278
Query: 287 QEMEVQ------EPAEPTGVNMLSPGESEHLLE-PAEAERSQRRRLLVPANE-GDPTETL 338
+ VQ P P L P + + P+ A L P + G P L
Sbjct: 279 KICTVQLVGNSWTPGYPETQEALCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMML 338
Query: 339 R---QCFDDFADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGR 395
+ Q +D D VP W+ +R LGL + EI+ + E RD Y ML +W + +
Sbjct: 339 QPGPQLYD-VMDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRW--RQQQ 395
Query: 396 DASVHTLLDALETLG 410
A + + ALE +G
Sbjct: 396 PAGLGAVYAALERMG 410
>gi|4507569 tumor necrosis factor receptor superfamily, member 25
isoform 2 precursor [Homo sapiens]
Length = 417
Score = 64.3 bits (155), Expect = 2e-10
Identities = 89/369 (24%), Positives = 140/369 (37%), Gaps = 57/369 (15%)
Query: 81 CPPGHHISEDGRD------CISCKYGQDYSTHWNDL--LFCLRCTRCD--SGEVELSPCT 130
CP GH++ + C+ C QD W + C RC CD + +V L C+
Sbjct: 51 CPAGHYLKAPCTEPCGNSTCLVCP--QDTFLAWENHHNSECARCQACDEQASQVALENCS 108
Query: 131 TTRNTVCQCEEGTFRE-------EDSPEMCRKC----------RTGCPRGMVKVGDCTPW 173
+T C C+ G F E SP C+ C R C R G C P
Sbjct: 109 AVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPG 168
Query: 174 SDIECVHKESGTKHSGEVPAVEETVTSSPGTPASPCSLSGII-IGVTVAAVVLIVAVFVC 232
E G G V T+ S P A+ C + + V +A +V+ + +
Sbjct: 169 ------FYEHG---DGCVSCPTSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGAT 219
Query: 233 KSLLWKKVLPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQ 292
+ ++ P+ + + G ++ + P + L+ ++L P E+ VQ
Sbjct: 220 LTYTYRHCWPHKPLVTADEAG----MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQ 275
Query: 293 ------EPAEPTGVNMLSPGESEHLLE-PAEAERSQRRRLLVPANE-GDPTETLR---QC 341
P P L P + + P+ A L P + G P L+ Q
Sbjct: 276 LVGNSWTPGYPETQEALCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQL 335
Query: 342 FDDFADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHT 401
+D D VP W+ +R LGL + EI+ + E RD Y ML +W + + A +
Sbjct: 336 YD-VMDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRW--RQQQPAGLGA 392
Query: 402 LLDALETLG 410
+ ALE +G
Sbjct: 393 VYAALERMG 401
>gi|4505039 lymphotoxin beta receptor [Homo sapiens]
Length = 435
Score = 62.0 bits (149), Expect = 1e-09
Identities = 56/193 (29%), Positives = 84/193 (43%), Gaps = 40/193 (20%)
Query: 81 CPPGHHISEDG---RD--CISCKYGQDYSTHWNDLLFCLRCTRCDS--GEVELSPCTTTR 133
CPPG ++S RD C +C Y+ HWN L C C CD G E++PCT+ R
Sbjct: 62 CPPGTYVSAKCSRIRDTVCATCAENS-YNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKR 120
Query: 134 NTVCQCEEGTFREEDSPEMCRKCR--TGCPRGM-VKVGDCTPWSDIECVHKESGTKHSGE 190
T C+C+ G F + E C C + CP G ++ D + CV ++G +
Sbjct: 121 KTQCRCQPGMFCAAWALE-CTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTS 179
Query: 191 VPAV----------EETVTSSPGTPAS-----------PCSLSGIIIGVTV----AAVVL 225
P+ + V ++PGT S P +SG ++ + V A +L
Sbjct: 180 SPSARCQPHTRCENQGLVEAAPGTAQSDTTCKNPLEPLPPEMSGTMLMLAVLLPLAFFLL 239
Query: 226 IVAVFVCKSLLWK 238
+ VF C +WK
Sbjct: 240 LATVFSC---IWK 249
Score = 36.6 bits (83), Expect = 0.047
Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 3/66 (4%)
Query: 116 CTRCDSGEVELSPCTTTRNTVC-QCEEGTFREE-DSPEMCRKCRTGCP-RGMVKVGDCTP 172
C+RC G + C+ R+TVC C E ++ E + +C+ CR P G+ ++ CT
Sbjct: 59 CSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTS 118
Query: 173 WSDIEC 178
+C
Sbjct: 119 KRKTQC 124
>gi|4507575 tumor necrosis factor receptor 1 precursor [Homo
sapiens]
Length = 455
Score = 58.9 bits (141), Expect = 9e-09
Identities = 101/434 (23%), Positives = 161/434 (37%), Gaps = 82/434 (18%)
Query: 34 VPKTLVLVVAAVLLLVSAESALITQQ----DLAPQQRAAPQQKRSSPSEGL-----CPPG 84
VP L+ +V LL+ S +I D + PQ K P C G
Sbjct: 6 VPDLLLPLVLLELLVGIYPSGVIGLVPHLGDREKRDSVCPQGKYIHPQNNSICCTKCHKG 65
Query: 85 HHISED------GRDCISCKYGQDYSTHWNDLLFCLRCTRC--DSGEVELSPCTTTRNTV 136
++ D DC C+ G ++ N L CL C++C + G+VE+S CT R+TV
Sbjct: 66 TYLYNDCPGPGQDTDCRECESGS-FTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTV 124
Query: 137 CQCEEGTFREEDSPEM--CRKCRTGCPRGMVKVGDCTPWSDIECVHKESGTKHSGEVPAV 194
C C + +R S + C C C G V + C + C T H+G
Sbjct: 125 CGCRKNQYRHYWSENLFQCFNCSL-CLNGTVHL-SCQEKQNTVC------TCHAGFFLRE 176
Query: 195 EETVTSSPGTPASPC---------SLSGIIIGVTVAAVVLIVAVFVC-KSLL-------- 236
E V+ S + C ++ G T + L++ +C SLL
Sbjct: 177 NECVSCSNCKKSLECTKLCLPQIENVKGTEDSGTTVLLPLVIFFGLCLLSLLFIGLMYRY 236
Query: 237 --WKKVLPYLKGICSGGGGDPER---VDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEV 291
WK L + +C G PE+ ++ ++ +P A + + P P
Sbjct: 237 QRWKSKLYSI--VC--GKSTPEKEGELEGTTTKPLAPNPSFSP-----TPGFTPTLGFSP 287
Query: 292 QEPAEPTGVNMLSPGESEHLLEPAEAERSQRR---RLLVPANEGDPTETLRQCFDDFA-- 346
+ T + +PG+ + P + +L A DP Q ++D A
Sbjct: 288 VPSSTFTSSSTYTPGDCPNFAAPRREVAPPYQGADPILATALASDPIPNPLQKWEDSAHK 347
Query: 347 ----------------DLVPFDSWEPLMRKLGLMDNEI-KVAKAEAAGHRDTLYTMLIKW 389
+ VP W+ +R+LGL D+EI ++ R+ Y+ML W
Sbjct: 348 PQSLDTDDPATLYAVVENVPPLRWKEFVRRLGLSDHEIDRLELQNGRCLREAQYSMLATW 407
Query: 390 VNKTGRDASVHTLL 403
+T R + LL
Sbjct: 408 RRRTPRREATLELL 421
>gi|23200025 tumor necrosis factor receptor superfamily, member 25
isoform 4 precursor [Homo sapiens]
Length = 372
Score = 54.7 bits (130), Expect = 2e-07
Identities = 80/330 (24%), Positives = 126/330 (38%), Gaps = 48/330 (14%)
Query: 111 LFCLRCTRCDSG-EVELSPCTTTRNTVCQCEEGTFRE-------EDSPEMCRKC------ 156
LFC C C + +V L C+ +T C C+ G F E SP C+ C
Sbjct: 45 LFC--CRGCPAASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGAL 102
Query: 157 ----RTGCPRGMVKVGDCTPWSDIECVHKESGTKHSGEVPAVEETVTSSPGTPASPCSLS 212
R C R G C P E G G V T+ S P A+ C
Sbjct: 103 HRHTRLLCSRRDTDCGTCLPG------FYEHG---DGCVSCPTSTLGSCPERCAAVCGWR 153
Query: 213 GII-IGVTVAAVVLIVAVFVCKSLLWKKVLPYLKGICSGGGGDPERVDRSSQRPGAEDNV 271
+ + V +A +V+ + + + ++ P+ + + G ++ + P +
Sbjct: 154 QMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAG----MEALTPPPATHLSP 209
Query: 272 LNEIVSILQPTQVPEQEMEVQ------EPAEPTGVNMLSPGESEHLLE-PAEAERSQRRR 324
L+ ++L P E+ VQ P P L P + + P+ A
Sbjct: 210 LDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSWDQLPSRALGPAAAP 269
Query: 325 LLVPANE-GDPTETLR---QCFDDFADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRD 380
L P + G P L+ Q +D D VP W+ +R LGL + EI+ + E RD
Sbjct: 270 TLSPESPAGSPAMMLQPGPQLYD-VMDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRD 328
Query: 381 TLYTMLIKWVNKTGRDASVHTLLDALETLG 410
Y ML +W + + A + + ALE +G
Sbjct: 329 QQYEMLKRW--RQQQPAGLGAVYAALERMG 356
>gi|4507577 tumor necrosis factor receptor 2 precursor [Homo
sapiens]
Length = 461
Score = 53.9 bits (128), Expect = 3e-07
Identities = 39/117 (33%), Positives = 50/117 (42%), Gaps = 17/117 (14%)
Query: 81 CPPGHHIS-----EDGRDCISCKYGQDYSTHWNDLLFCLRC-TRCDSGEVELSPCTTTRN 134
C PG H C SC+ Y+ WN + CL C +RC S +VE CT +N
Sbjct: 57 CSPGQHAKVFCTKTSDTVCDSCE-DSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQN 115
Query: 135 TVCQCEEGTFREEDSPEMC------RKCRTGCPRGMVKVGDCTPWSDIECVHKESGT 185
+C C G + E C RKCR G G+ + G T SD+ C GT
Sbjct: 116 RICTCRPGWYCALSKQEGCRLCAPLRKCRPGF--GVARPG--TETSDVVCKPCAPGT 168
Score = 35.4 bits (80), Expect = 0.10
Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 4/59 (6%)
Query: 116 CTRCDSGEVELSPCTTTRNTVC-QCEEGTFRE--EDSPEMCRKCRTGCPRGMVKVGDCT 171
C++C G+ CT T +TVC CE+ T+ + PE C C + C V+ CT
Sbjct: 54 CSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPE-CLSCGSRCSSDQVETQACT 111
>gi|23200041 tumor necrosis factor receptor superfamily, member 14
precursor [Homo sapiens]
Length = 283
Score = 50.1 bits (118), Expect = 4e-06
Identities = 51/171 (29%), Positives = 64/171 (37%), Gaps = 21/171 (12%)
Query: 27 GARPGPRVPKTLVLVVAAVLLLVSAESALITQQDLAPQQRAAPQQKRSSPSEGL--CPPG 84
G P PKT VL + L + A AP + + + SE C PG
Sbjct: 8 GPPPWRSTPKTDVLRLVLYLTFLGAPC-------YAPALPSCKEDEYPVGSECCPKCSPG 60
Query: 85 HHISE-----DGRDCISCKYGQDYSTHWNDLLFCLRCTRCDS--GEVELSPCTTTRNTVC 137
+ + E G C C G Y H N L CL+C CD G C+ T N VC
Sbjct: 61 YRVKEACGELTGTVCEPCPPGT-YIAHLNGLSKCLQCQMCDPAMGLRASRNCSRTENAVC 119
Query: 138 QCEEGTF---REEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKESGT 185
C G F ++ D CR T P V+ G T D C + GT
Sbjct: 120 GCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGG-TESQDTLCQNCPPGT 169
>gi|4505393 nerve growth factor receptor precursor [Homo sapiens]
Length = 427
Score = 49.7 bits (117), Expect = 5e-06
Identities = 40/135 (29%), Positives = 59/135 (43%), Gaps = 12/135 (8%)
Query: 97 CKYG--QDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQ-CEEGTFREE-DSPEM 152
C YG QD +T C C C++G + C +NTVC+ C +GT+ +E + +
Sbjct: 109 CAYGYYQDETTGR-----CEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDP 163
Query: 153 CRKCRTGCPRGMVKVGDCTPWSDIECVHKESGTKHSGEVPAVEETVTSSPGTPASPCSLS 212
C C T C ++ +CT W+D EC P ++ S P +P
Sbjct: 164 CLPC-TVCEDTERQLRECTRWADAECEEIPGRWITRSTPPEGSDSTAPSTQEPEAPPEQD 222
Query: 213 GIIIGVTVAAVVLIV 227
+I TVA VV V
Sbjct: 223 --LIASTVAGVVTTV 235
Score = 30.8 bits (68), Expect = 2.6
Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 1/57 (1%)
Query: 94 CISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSP 150
C C G YS N + CL CT C+ E +L CT + C+ G + +P
Sbjct: 146 CEECPDGT-YSDEANHVDPCLPCTVCEDTERQLRECTRWADAECEEIPGRWITRSTP 201
>gi|148743793 osteoprotegerin precursor [Homo sapiens]
Length = 401
Score = 47.4 bits (111), Expect = 3e-05
Identities = 39/142 (27%), Positives = 59/142 (41%), Gaps = 18/142 (12%)
Query: 81 CPPGHHISEDGRD-----CISCKYGQDYSTHWNDLLFCLRCTR-CDSGEVELSPCTTTRN 134
CPPG ++ + C C Y+ W+ CL C+ C + C T N
Sbjct: 44 CPPGTYLKQHCTAKWKTVCAPCP-DHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHN 102
Query: 135 TVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKESGTKHSGEVPAV 194
VC+C+EG + E E C K R+ CP G V TP + C G +
Sbjct: 103 RVCECKEGRYLE---IEFCLKHRS-CPPGFGVVQAGTPERNTVCKRCPDGFFSN------ 152
Query: 195 EETVTSSPGTPASPCSLSGIII 216
ET + +P + CS+ G+++
Sbjct: 153 -ETSSKAPCRKHTNCSVFGLLL 173
>gi|7657039 tumor necrosis factor receptor superfamily, member 21
precursor [Homo sapiens]
Length = 655
Score = 46.2 bits (108), Expect = 6e-05
Identities = 25/67 (37%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Query: 114 LRCTRCDSGEVELSPCTTTRNTVCQ-CEEGTF-REEDSPEMCRKCRTGCPRGMVKVGDCT 171
L C +C +G CT T VC C GTF R E+ E C C CP M++ C
Sbjct: 65 LTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKLPCA 124
Query: 172 PWSDIEC 178
+D EC
Sbjct: 125 ALTDREC 131
Score = 43.1 bits (100), Expect = 5e-04
Identities = 40/163 (24%), Positives = 60/163 (36%), Gaps = 36/163 (22%)
Query: 81 CPPGHHISEDG-----RDCISCKYGQDYSTHWNDLLFCLRCTR-CDSGEVELSPCTTTRN 134
CP G ++SE R C SC G ++ H N + C C++ C +E PC +
Sbjct: 70 CPAGTYVSEHCTNTSLRVCSSCPVGT-FTRHENGIEKCHDCSQPCPWPMIEKLPCAALTD 128
Query: 135 TVCQCEEGTFRE---------------------EDSPEMCRKCRTG----CPRGMVKVGD 169
C C G F+ E C++C G P ++K
Sbjct: 129 RECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKCKA 188
Query: 170 CTPWSDIECVHKESGTKHS----GEVPAVEETVTSSPGTPASP 208
T V + GTK + G +P+ + + SPGT P
Sbjct: 189 YTDCLSQNLVVIKPGTKETDNVCGTLPSFSSSTSPSPGTAIFP 231
>gi|68348711 tumor necrosis factor receptor superfamily, member 8
isoform 1 precursor [Homo sapiens]
Length = 595
Score = 43.9 bits (102), Expect = 3e-04
Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 9/107 (8%)
Query: 113 CLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKC--RTGCPRGMVKVGDC 170
C+ C+R D VE +PC + VC+C G F + C +C + CP GM+
Sbjct: 84 CVTCSRDDL--VEKTPCAWNSSRVCECRPGMFCSTSAVNSCARCFFHSVCPAGMIVKFPG 141
Query: 171 TPWSDIECVHKESGTKHSGEVP-----AVEETVTSSPGTPASPCSLS 212
T + C G + P T+ + TP SP + S
Sbjct: 142 TAQKNTVCEPASPGVSPACASPENCKEPSSGTIPQAKPTPVSPATSS 188
Score = 30.8 bits (68), Expect = 2.6
Identities = 26/106 (24%), Positives = 40/106 (37%), Gaps = 4/106 (3%)
Query: 113 CLRC---TRCDSGEVELSPCTTTRNTVCQ-CEEGTFREEDSPEMCRKCRTGCPRGMVKVG 168
C RC + C +G + P T +NTVC+ G SPE C++ +G
Sbjct: 122 CARCFFHSVCPAGMIVKFPGTAQKNTVCEPASPGVSPACASPENCKEPSSGTIPQAKPTP 181
Query: 169 DCTPWSDIECVHKESGTKHSGEVPAVEETVTSSPGTPASPCSLSGI 214
S + GT+ + E + SP + P S G+
Sbjct: 182 VSPATSSASTMPVRGGTRLAQEAASKLTRAPDSPSSVGRPSSDPGL 227
Score = 29.6 bits (65), Expect = 5.7
Identities = 30/138 (21%), Positives = 44/138 (31%), Gaps = 11/138 (7%)
Query: 8 APAASGARKRHGPGPREARGARPGPRVPKTL---VLVVAAVLLLVSAESALITQQDLAPQ 64
+PA + P A+P P P T + V L ++ +T+ +P
Sbjct: 157 SPACASPENCKEPSSGTIPQAKPTPVSPATSSASTMPVRGGTRLAQEAASKLTRAPDSPS 216
Query: 65 QRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSGEV 124
P CP G DC Y C+ C+R D V
Sbjct: 217 SVGRPSSDPGLSPTQPCPEG------SGDCRKQCEPDYYLDEAGRCTACVSCSRDDL--V 268
Query: 125 ELSPCTTTRNTVCQCEEG 142
E +PC + C+C G
Sbjct: 269 EKTPCAWNSSRTCECRPG 286
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 42.4 bits (98), Expect = 8e-04
Identities = 52/177 (29%), Positives = 71/177 (40%), Gaps = 36/177 (20%)
Query: 81 CPPGHHISEDGRDCISCKYGQDYSTH-WNDLLFCLR------CTR-CDSGEVELSPCTTT 132
C PG + G+ C+ CK H N +CL C++ C G + C T
Sbjct: 610 CQPGRY----GKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGEN-CAQT 664
Query: 133 RNTVCQCEEG-TFREEDSPEMC------RKCRTGCPRGMVKVGDCTPWS--DIECVHKES 183
CQC G T +D +C C GCP G P E H E+
Sbjct: 665 ----CQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPET 720
Query: 184 GT-----KHSGEVP--AVEETVTSSPGTPASPCSLSGIIIGVTV--AAVVLIVAVFV 231
G HSG ++E T P TP + SL G +IG+ V + VV +VA+F+
Sbjct: 721 GACVCPPGHSGAPCRIGIQEPFTVMPTTPVAYNSL-GAVIGIAVLGSLVVALVALFI 776
>gi|4507579 tumor necrosis factor receptor superfamily, member 4
precursor [Homo sapiens]
Length = 277
Score = 42.4 bits (98), Expect = 8e-04
Identities = 34/111 (30%), Positives = 47/111 (42%), Gaps = 14/111 (12%)
Query: 113 CLRCTRCD--SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGD- 169
C CT C+ SG CT T++TVC+C GT + DS + C CP G GD
Sbjct: 81 CKPCTWCNLRSGSERKQLCTATQDTVCRCRAGT-QPLDSYKPGVDC-APCPPGHFSPGDN 138
Query: 170 --CTPWSDIECVHKESGTKHSGEVPAVEE-------TVTSSPGTPASPCSL 211
C PW++ K + S A+ E + G PA P ++
Sbjct: 139 QACKPWTNCTLAGKHTLQPASNSSDAICEDRDPPATQPQETQGPPARPITV 189
Score = 35.4 bits (80), Expect = 0.10
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 20/100 (20%)
Query: 116 CTRCDSGEVELSPCTTTRNTVCQ-CEEGTFREEDSPEMCRKC-----RTGCPRGMVKVGD 169
C C G +S C+ ++NTVC+ C G + + S + C+ C R+G R +
Sbjct: 43 CHECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGSERKQL---- 98
Query: 170 CTPWSDIECVHKESGTKHSGEVPAVEETVTSSPGTPASPC 209
CT D C +GT + + PG +PC
Sbjct: 99 CTATQDTVC-RCRAGT---------QPLDSYKPGVDCAPC 128
>gi|23200031 tumor necrosis factor receptor superfamily, member 25
isoform 7 precursor [Homo sapiens]
Length = 234
Score = 41.6 bits (96), Expect = 0.001
Identities = 23/67 (34%), Positives = 34/67 (50%), Gaps = 2/67 (2%)
Query: 344 DFADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLL 403
D D VP W+ +R LGL + EI+ + E RD Y ML +W + + A + +
Sbjct: 154 DVMDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRW--RQQQPAGLGAVY 211
Query: 404 DALETLG 410
ALE +G
Sbjct: 212 AALERMG 218
>gi|23200023 tumor necrosis factor receptor superfamily, member 25
isoform 3 precursor [Homo sapiens]
Length = 380
Score = 41.6 bits (96), Expect = 0.001
Identities = 23/67 (34%), Positives = 34/67 (50%), Gaps = 2/67 (2%)
Query: 344 DFADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLL 403
D D VP W+ +R LGL + EI+ + E RD Y ML +W + + A + +
Sbjct: 300 DVMDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRW--RQQQPAGLGAVY 357
Query: 404 DALETLG 410
ALE +G
Sbjct: 358 AALERMG 364
>gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]
Length = 277
Score = 40.8 bits (94), Expect = 0.002
Identities = 51/209 (24%), Positives = 79/209 (37%), Gaps = 49/209 (23%)
Query: 63 PQQRAAPQQKR---SSPSEGLCPPGHHISED-----GRDCISCKYGQDYSTHWNDLLFCL 114
P+ A ++K+ +S LC PG + D +C+ C + T WN C
Sbjct: 20 PEPPTACREKQYLINSQCCSLCQPGQKLVSDCTEFTETECLPCGESEFLDT-WNRETHCH 78
Query: 115 RCTRCDS--GEVELSPCTTTRNTVCQCEEGTFREEDSPEMC---RKCRTG---------- 159
+ CD G T+ +T+C CEEG ++ E C R C G
Sbjct: 79 QHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQIATGV 138
Query: 160 -------CPRGMVK-----VGDCTPWSDIE---CVHKESGTKHSGEVPAVEETVTSSPGT 204
CP G C PW+ E V +++GT + V ++ + +
Sbjct: 139 SDTICEPCPVGFFSNVSSAFEKCHPWTSCETKDLVVQQAGTNKTDVVCGPQDRLRALVVI 198
Query: 205 PASPCSLSGIIIGVTVAAVVLIVAVFVCK 233
P II G+ A +L+V VF+ K
Sbjct: 199 P--------IIFGILFA--ILLVLVFIKK 217
>gi|14790170 tumor necrosis factor receptor superfamily, member 6b
[Homo sapiens]
Length = 300
Score = 38.1 bits (87), Expect = 0.016
Identities = 41/152 (26%), Positives = 56/152 (36%), Gaps = 31/152 (20%)
Query: 72 KRSSPSE-GLCPPGHHIS-------------------EDGRDCIS-----CKYGQDYSTH 106
+R SP+ G CPP H+ E+ R C + C+ + H
Sbjct: 63 RRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAH 122
Query: 107 WNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQ-CEEGTF-REEDSPEMCRKCRTGCPRGM 164
FCL C G ++P T ++NT CQ C GTF S E C+ R G+
Sbjct: 123 AG---FCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGL 179
Query: 165 VKVGDCTPWSDIECVHKESGTKHSGEVPAVEE 196
+ D C +G S VP EE
Sbjct: 180 ALNVPGSSSHDTLCT-SCTGFPLSTRVPGAEE 210
>gi|4507565 tumor necrosis factor receptor superfamily, member 11a
precursor [Homo sapiens]
Length = 616
Score = 38.1 bits (87), Expect = 0.016
Identities = 52/221 (23%), Positives = 79/221 (35%), Gaps = 39/221 (17%)
Query: 44 AVLLLVSAESALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHHISED---GRDCISCKYG 100
A+LLL + + L +AP + + C PG ++S D + G
Sbjct: 13 ALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKCTTTSDSVCLPCG 72
Query: 101 QD-YSTHWNDLLFCLRCTRCDSGE--VELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCR 157
D Y WN+ CL CD+G+ V + +T C C G +D E CR+
Sbjct: 73 PDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHWSQDC-ECCRR-N 130
Query: 158 TGCPRGM--------------------------VKVGDCTPWSDIECVHK---ESGTKHS 188
T C G+ C PW++ + K GT+ S
Sbjct: 131 TECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGKRVEHHGTEKS 190
Query: 189 GEVPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAV 229
V + P P L G+II + A+V L+ A+
Sbjct: 191 DAVCSSSLPARKPPNEP--HVYLPGLIILLLFASVALVAAI 229
>gi|4507585 tumor necrosis factor receptor superfamily, member 6b
[Homo sapiens]
Length = 300
Score = 38.1 bits (87), Expect = 0.016
Identities = 41/152 (26%), Positives = 56/152 (36%), Gaps = 31/152 (20%)
Query: 72 KRSSPSE-GLCPPGHHIS-------------------EDGRDCIS-----CKYGQDYSTH 106
+R SP+ G CPP H+ E+ R C + C+ + H
Sbjct: 63 RRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAH 122
Query: 107 WNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQ-CEEGTF-REEDSPEMCRKCRTGCPRGM 164
FCL C G ++P T ++NT CQ C GTF S E C+ R G+
Sbjct: 123 AG---FCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGL 179
Query: 165 VKVGDCTPWSDIECVHKESGTKHSGEVPAVEE 196
+ D C +G S VP EE
Sbjct: 180 ALNVPGSSSHDTLCT-SCTGFPLSTRVPGAEE 210
>gi|221316650 ephrin receptor EphA1 [Homo sapiens]
Length = 976
Score = 37.7 bits (86), Expect = 0.021
Identities = 31/125 (24%), Positives = 47/125 (37%), Gaps = 17/125 (13%)
Query: 48 LVSAESALITQQDLAPQQRAAPQQKRSSPSEGL-------CPPGHHISEDGRDCISCKYG 100
LV + +P+ AP+ S E L C PG+ G C++C G
Sbjct: 224 LVEVAGTCLPHARASPRPSGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSG 283
Query: 101 QDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREE-DSPEMCRKCRTG 159
Y D CL C + + E E + T+C CE G +R + P++
Sbjct: 284 -SYRMDM-DTPHCLTCPQQSTAESEGA-------TICTCESGHYRAPGEGPQVACTGPPS 334
Query: 160 CPRGM 164
PR +
Sbjct: 335 APRNL 339
>gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]
Length = 203
Score = 35.4 bits (80), Expect = 0.10
Identities = 30/110 (27%), Positives = 45/110 (40%), Gaps = 14/110 (12%)
Query: 63 PQQRAAPQQKR---SSPSEGLCPPGHHISED-----GRDCISCKYGQDYSTHWNDLLFCL 114
P+ A ++K+ +S LC PG + D +C+ C + T WN C
Sbjct: 20 PEPPTACREKQYLINSQCCSLCQPGQKLVSDCTEFTETECLPCGESEFLDT-WNRETHCH 78
Query: 115 RCTRCDS--GEVELSPCTTTRNTVCQCEEGTFREEDSPEMC---RKCRTG 159
+ CD G T+ +T+C CEEG ++ E C R C G
Sbjct: 79 QHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCTSEACESCVLHRSCSPG 128
>gi|145312251 EPH receptor A6 isoform a [Homo sapiens]
Length = 1130
Score = 35.4 bits (80), Expect = 0.10
Identities = 29/108 (26%), Positives = 46/108 (42%), Gaps = 15/108 (13%)
Query: 64 QQRAAPQQKRSSPSEGLCPPGHHISEDGRD-----CISCKYGQDYSTHWNDLLFCLRCTR 118
++R P+ + + L P G I G + C +C+ G + N +C++
Sbjct: 335 EERDTPKLYCGADGDWLVPLGRCICSTGYEEIEGSCHACRPGFYKAFAGNT-----KCSK 389
Query: 119 CDSGEVELSPCTTTRNTVCQCEEGTFR-EEDSPEMCRKCRTGCPRGMV 165
C + T+ VCQCE+G FR E+D P M PR +V
Sbjct: 390 CPPHSLTYMEATS----VCQCEKGYFRAEKDPPSMACTRPPSAPRNVV 433
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,374,576
Number of Sequences: 37866
Number of extensions: 1073247
Number of successful extensions: 4693
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 80
Number of HSP's that attempted gapping in prelim test: 4504
Number of HSP's gapped (non-prelim): 235
length of query: 440
length of database: 18,247,518
effective HSP length: 105
effective length of query: 335
effective length of database: 14,271,588
effective search space: 4780981980
effective search space used: 4780981980
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.