Guide to the Human Genome
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Search of human proteins with 18641360

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18641360 collectin sub-family member 12 [Homo sapiens]
         (742 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18641360 collectin sub-family member 12 [Homo sapiens]            1526   0.0  
gi|33598924 scavenger receptor class A, member 3 isoform 1 [Homo...   351   1e-96
gi|33598922 scavenger receptor class A, member 3 isoform 2 [Homo...   196   5e-50
gi|61699226 pulmonary surfactant-associated protein D precursor ...   180   4e-45
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]       175   2e-43
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      172   1e-42
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     171   3e-42
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   169   9e-42
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   169   9e-42
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   169   9e-42
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]               168   1e-41
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   168   2e-41
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   168   2e-41
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...   166   6e-41
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...   166   6e-41
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...   166   6e-41
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...   166   6e-41
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     166   7e-41
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]      166   9e-41
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]   165   2e-40
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         162   1e-39
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]          162   1e-39
gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens]              162   1e-39
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...   162   1e-39
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...   162   1e-39
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...   162   1e-39
gi|48762934 alpha 2 type I collagen [Homo sapiens]                    161   2e-39
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]              161   2e-39
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   160   3e-39
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   160   4e-39

>gi|18641360 collectin sub-family member 12 [Homo sapiens]
          Length = 742

 Score = 1526 bits (3950), Expect = 0.0
 Identities = 742/742 (100%), Positives = 742/742 (100%)

Query: 1   MKDDFAEEEEVQSFGYKRFGIQEGTQCTKCKNNWALKFSIILLYILCALLTITVAILGYK 60
           MKDDFAEEEEVQSFGYKRFGIQEGTQCTKCKNNWALKFSIILLYILCALLTITVAILGYK
Sbjct: 1   MKDDFAEEEEVQSFGYKRFGIQEGTQCTKCKNNWALKFSIILLYILCALLTITVAILGYK 60

Query: 61  VVEKMDNVTGGMETSRQTYDDKLTAVESDLKKLGDQTGKKAISTNSELSTFRSDILDLRQ 120
           VVEKMDNVTGGMETSRQTYDDKLTAVESDLKKLGDQTGKKAISTNSELSTFRSDILDLRQ
Sbjct: 61  VVEKMDNVTGGMETSRQTYDDKLTAVESDLKKLGDQTGKKAISTNSELSTFRSDILDLRQ 120

Query: 121 QLREITEKTSKNKDTLEKLQASGDALVDRQSQLKETLENNSFLITTVNKTLQAYNGYVTN 180
           QLREITEKTSKNKDTLEKLQASGDALVDRQSQLKETLENNSFLITTVNKTLQAYNGYVTN
Sbjct: 121 QLREITEKTSKNKDTLEKLQASGDALVDRQSQLKETLENNSFLITTVNKTLQAYNGYVTN 180

Query: 181 LQQDTSVLQGNLQNQMYSHNVVIMNLNNLNLTQVQQRNLITNLQRSVDDTSQAIQRIKND 240
           LQQDTSVLQGNLQNQMYSHNVVIMNLNNLNLTQVQQRNLITNLQRSVDDTSQAIQRIKND
Sbjct: 181 LQQDTSVLQGNLQNQMYSHNVVIMNLNNLNLTQVQQRNLITNLQRSVDDTSQAIQRIKND 240

Query: 241 FQNLQQVFLQAKKDTDWLKEKVQSLQTLAANNSALAKANNDTLEDMNSQLNSFTGQMENI 300
           FQNLQQVFLQAKKDTDWLKEKVQSLQTLAANNSALAKANNDTLEDMNSQLNSFTGQMENI
Sbjct: 241 FQNLQQVFLQAKKDTDWLKEKVQSLQTLAANNSALAKANNDTLEDMNSQLNSFTGQMENI 300

Query: 301 TTISQANEQNLKDLQDLHKDAENRTAIKFNQLEERFQLFETDIVNIISNISYTAHHLRTL 360
           TTISQANEQNLKDLQDLHKDAENRTAIKFNQLEERFQLFETDIVNIISNISYTAHHLRTL
Sbjct: 301 TTISQANEQNLKDLQDLHKDAENRTAIKFNQLEERFQLFETDIVNIISNISYTAHHLRTL 360

Query: 361 TSNLNEVRTTCTDTLTKHTDDLTSLNNTLANIRLDSVSLRMQQDLMRSRLDTEVANLSVI 420
           TSNLNEVRTTCTDTLTKHTDDLTSLNNTLANIRLDSVSLRMQQDLMRSRLDTEVANLSVI
Sbjct: 361 TSNLNEVRTTCTDTLTKHTDDLTSLNNTLANIRLDSVSLRMQQDLMRSRLDTEVANLSVI 420

Query: 421 MEEMKLVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGP 480
           MEEMKLVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGP
Sbjct: 421 MEEMKLVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGP 480

Query: 481 AGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP 540
           AGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP
Sbjct: 481 AGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP 540

Query: 541 QGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP 600
           QGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP
Sbjct: 541 QGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP 600

Query: 601 APEDNGCPPHWKNFTDKCYYFSVEKEIFEDAKLFCEDKSSHLVFINTREEQQWIKKQMVG 660
           APEDNGCPPHWKNFTDKCYYFSVEKEIFEDAKLFCEDKSSHLVFINTREEQQWIKKQMVG
Sbjct: 601 APEDNGCPPHWKNFTDKCYYFSVEKEIFEDAKLFCEDKSSHLVFINTREEQQWIKKQMVG 660

Query: 661 RESHWIGLTDSERENEWKWLDGTSPDYKNWKAGQPDNWGHGHGPGEDCAGLIYAGQWNDF 720
           RESHWIGLTDSERENEWKWLDGTSPDYKNWKAGQPDNWGHGHGPGEDCAGLIYAGQWNDF
Sbjct: 661 RESHWIGLTDSERENEWKWLDGTSPDYKNWKAGQPDNWGHGHGPGEDCAGLIYAGQWNDF 720

Query: 721 QCEDVNNFICEKDRETVLSSAL 742
           QCEDVNNFICEKDRETVLSSAL
Sbjct: 721 QCEDVNNFICEKDRETVLSSAL 742


>gi|33598924 scavenger receptor class A, member 3 isoform 1 [Homo
           sapiens]
          Length = 606

 Score =  351 bits (901), Expect = 1e-96
 Identities = 203/587 (34%), Positives = 324/587 (55%), Gaps = 2/587 (0%)

Query: 2   KDDFAEEEEVQSFGYKRFGIQEGTQCTKCKNNWALKFSIILLYILCALLTITVAILGYKV 61
           +D   ++E++ +F   + G + G +C++C+ N +L  S+ +LY+  ALL + VA+L   V
Sbjct: 18  EDLAGDDEDMPTFPCTQKG-RPGPRCSRCQKNLSLHTSVRILYLFLALLLVAVAVLASLV 76

Query: 62  VEKMDNVTGGMETSRQTYDDKLTAVESDLKKLGDQTGKKAISTNSELSTFRSDILDLRQQ 121
             K+D+++  +  ++  YD KL  ++ +L+ L D       S   E      +I  L+++
Sbjct: 77  FRKVDSLSEDISLTQSIYDKKLVLMQKNLQGL-DPKALNNCSFCHEAGQLGPEIRKLQEE 135

Query: 122 LREITEKTSKNKDTLEKLQASGDALVDRQSQLKETLENNSFLITTVNKTLQAYNGYVTNL 181
           L  I +     +  L++   + + L     Q+ + + + SF I  VN++L  +   V   
Sbjct: 136 LEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQVNQSLGLFLAQVRGW 195

Query: 182 QQDTSVLQGNLQNQMYSHNVVIMNLNNLNLTQVQQRNLITNLQRSVDDTSQAIQRIKNDF 241
           Q  T+ L  +L++       V   ++ +N T  Q    I  +QR  D+ +  +Q+I  D+
Sbjct: 196 QATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRKTDEETLTLQKIVTDW 255

Query: 242 QNLQQVFLQAKKDTDWLKEKVQSLQTLAANNSALAKANNDTLEDMNSQLNSFTGQMENIT 301
           QN  ++F   +  +    E V+++Q     +S     N++++ D+  Q+     Q++NI+
Sbjct: 256 QNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDLVLQVMGLQLQLDNIS 315

Query: 302 TISQANEQNLKDLQDLHKDAENRTAIKFNQLEERFQLFETDIVNIISNISYTAHHLRTLT 361
           +    +E+N+ DLQ     A+NRT  +F  LE R    E +I  I +NI+ T +H+ ++ 
Sbjct: 316 SFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTIFTNINATDNHVHSML 375

Query: 362 SNLNEVRTTCTDTLTKHTDDLTSLNNTLANIRLDSVSLRMQQDLMRSRLDTEVANLSVIM 421
             L++VR +CT     H ++L  LN +++ +   +  LR +  L+ +RLD  V NLS+I+
Sbjct: 376 KYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLLSARLDLNVRNLSMIV 435

Query: 422 EEMKLVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPA 481
           EEMK VD++HG++++N TIL+G PGP GPRG +G  G  GP G +G KG+ G  GP GP 
Sbjct: 436 EEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQ 495

Query: 482 GERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQ 541
           G +G  G AGP GERG  G +G  G KGS+GS G  GP+G  G  G  GPPG EG PG  
Sbjct: 496 GPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP 555

Query: 542 GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588
           GP G QG  G  G+ G PG RG  G  G PG+ GP G PGPPGP G+
Sbjct: 556 GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 25/53 (47%), Positives = 25/53 (47%), Gaps = 3/53 (5%)

Query: 554 GEPGVPGPRGLPGLPGVPGMPG---PKGPPGPPGPSGAVVPLALQNEPTPAPE 603
           G PG PGPRG  G  GV G  G   PKG PG  GP G   P     E  P  E
Sbjct: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509


>gi|33598922 scavenger receptor class A, member 3 isoform 2 [Homo
           sapiens]
          Length = 466

 Score =  196 bits (499), Expect = 5e-50
 Identities = 125/442 (28%), Positives = 236/442 (53%), Gaps = 2/442 (0%)

Query: 2   KDDFAEEEEVQSFGYKRFGIQEGTQCTKCKNNWALKFSIILLYILCALLTITVAILGYKV 61
           +D   ++E++ +F   + G + G +C++C+ N +L  S+ +LY+  ALL + VA+L   V
Sbjct: 18  EDLAGDDEDMPTFPCTQKG-RPGPRCSRCQKNLSLHTSVRILYLFLALLLVAVAVLASLV 76

Query: 62  VEKMDNVTGGMETSRQTYDDKLTAVESDLKKLGDQTGKKAISTNSELSTFRSDILDLRQQ 121
             K+D+++  +  ++  YD KL  ++ +L+ L D       S   E      +I  L+++
Sbjct: 77  FRKVDSLSEDISLTQSIYDKKLVLMQKNLQGL-DPKALNNCSFCHEAGQLGPEIRKLQEE 135

Query: 122 LREITEKTSKNKDTLEKLQASGDALVDRQSQLKETLENNSFLITTVNKTLQAYNGYVTNL 181
           L  I +     +  L++   + + L     Q+ + + + SF I  VN++L  +   V   
Sbjct: 136 LEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQVNQSLGLFLAQVRGW 195

Query: 182 QQDTSVLQGNLQNQMYSHNVVIMNLNNLNLTQVQQRNLITNLQRSVDDTSQAIQRIKNDF 241
           Q  T+ L  +L++       V   ++ +N T  Q    I  +QR  D+ +  +Q+I  D+
Sbjct: 196 QATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRKTDEETLTLQKIVTDW 255

Query: 242 QNLQQVFLQAKKDTDWLKEKVQSLQTLAANNSALAKANNDTLEDMNSQLNSFTGQMENIT 301
           QN  ++F   +  +    E V+++Q     +S     N++++ D+  Q+     Q++NI+
Sbjct: 256 QNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDLVLQVMGLQLQLDNIS 315

Query: 302 TISQANEQNLKDLQDLHKDAENRTAIKFNQLEERFQLFETDIVNIISNISYTAHHLRTLT 361
           +    +E+N+ DLQ     A+NRT  +F  LE R    E +I  I +NI+ T +H+ ++ 
Sbjct: 316 SFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTIFTNINATDNHVHSML 375

Query: 362 SNLNEVRTTCTDTLTKHTDDLTSLNNTLANIRLDSVSLRMQQDLMRSRLDTEVANLSVIM 421
             L++VR +CT     H ++L  LN +++ +   +  LR +  L+ +RLD  V NLS+I+
Sbjct: 376 KYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLLSARLDLNVRNLSMIV 435

Query: 422 EEMKLVDSKHGQLIKNFTILQG 443
           EEMK VD++HG++++N TIL+G
Sbjct: 436 EEMKAVDTQHGEILRNVTILRG 457


>gi|61699226 pulmonary surfactant-associated protein D precursor
           [Homo sapiens]
          Length = 375

 Score =  180 bits (457), Expect = 4e-45
 Identities = 106/302 (35%), Positives = 149/302 (49%), Gaps = 15/302 (4%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
           + G  GP GP+GD GS G PGP G+ G  G  G PG PGPAG  GP+G  G  G +G  G
Sbjct: 77  MPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGREGPLGKQGNIGPQGKPG 136

Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP---PGKEGLPGPQGPPGFQGLQGTVGEPG 557
            KG  GPKG  G+PG  G  G  G  GP G    PG+ G+PG  G  G  G  G  G PG
Sbjct: 137 PKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTGAAGSAGAMGPQGSPG 196

Query: 558 VPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPL-ALQNEPTPAP------EDNGCPPH 610
             GP GL G  G+PG  G KG  G P  +     + ALQ +           +     P+
Sbjct: 197 ARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHLQAAFSQYKKVELFPN 256

Query: 611 WKNFTDKCYYFSVEKEIFEDAKLFCEDKSSHLVFINTREEQQWIKKQMVGR-ESHWIGLT 669
            ++  +K +  +   + F +A+L C      L    +  E   +++ +V + E+ ++ +T
Sbjct: 257 GQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAALQQLVVAKNEAAFLSMT 316

Query: 670 DSERENEWKWLDGTSPDYKNWKAGQPDNWGHGHGPGEDCAGLIYAGQWNDFQCEDVNNFI 729
           DS+ E ++ +  G S  Y NW  G+P++     G  EDC  +   G+WND  C +    +
Sbjct: 317 DSKTEGKFTYPTGESLVYSNWAPGEPND----DGGSEDCVEIFTNGKWNDRACGEKRLVV 372

Query: 730 CE 731
           CE
Sbjct: 373 CE 374



 Score = 93.2 bits (230), Expect = 8e-19
 Identities = 48/103 (46%), Positives = 57/103 (55%), Gaps = 3/103 (2%)

Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPG 560
           S    G  G  G  G+ GP+G  GDPG PG  G+ G+PG  GP G +G  G+VGEPG  G
Sbjct: 41  SSVESGLPGRDGRDGREGPRGEKGDPGLPGAAGQAGMPGQAGPVGPKGDNGSVGEPGPKG 100

Query: 561 PRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPE 603
             G  G PG PG+PGP G  GP G  G + P   Q +P P  E
Sbjct: 101 DTGPSGPPGPPGVPGPAGREGPLGKQGNIGP---QGKPGPKGE 140


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score =  175 bits (443), Expect = 2e-43
 Identities = 90/179 (50%), Positives = 103/179 (57%), Gaps = 18/179 (10%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
            L GPPGP GPRG+RG QG  G  G++G +G+ G PGPPGP G  G +G  GPPG +  KG
Sbjct: 1127 LPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKG 1186

Query: 501  SKGSQGPKGSRGSPGKPGP---QGPS---------------GDPGPPGPPGKEGLPGPQG 542
            S+G +GP G  GSPG PGP   QGP+               GDPGP GPPG  G PG +G
Sbjct: 1187 SEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKG 1246

Query: 543  PPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601
              G  GL G  G+ G PGP G  G PG  G PG  GP G PGP G V P     +P PA
Sbjct: 1247 KTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPA 1305



 Score =  167 bits (423), Expect = 3e-41
 Identities = 83/162 (51%), Positives = 98/162 (60%), Gaps = 12/162 (7%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKG------EKGEPGPPGPAGERGPIGPAGPPGE 495
            +G PGP G  G  G+ GPPG  G KG++G      EKGEPGPPG  G  GP GPAGP GE
Sbjct: 1080 KGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGE 1139

Query: 496  RGGKGSKGSQGPKGSRGSPGKPGPQGPSG------DPGPPGPPGKEGLPGPQGPPGFQGL 549
            RG +G+ G +G +G +G PG PGP GP G       PGPPGP  ++G  G +GP G  G 
Sbjct: 1140 RGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGS 1199

Query: 550  QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
             G  G PG+ GP GL GL G  G PG +G PGP GP G + P
Sbjct: 1200 PGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGP 1241



 Score =  157 bits (396), Expect = 4e-38
 Identities = 91/204 (44%), Positives = 107/204 (52%), Gaps = 31/204 (15%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKG------EKGEPGPPGPAGERGPIGPAGPPGER 496
            GPPGP GP G  G+ G PG  G +G++G      +KGEPGPPG  G  G  GP G PG +
Sbjct: 1045 GPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIK 1104

Query: 497  GGKG------SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG---------LPGPQ 541
            G +G       KG  GP GS G PG PGP GP G+ GP G  G++G          PGP 
Sbjct: 1105 GERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPP 1164

Query: 542  GPPGFQGLQGTVGEP---------GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPL 592
            GPPGF G  G+ G P         G+ GP GLPG PG PG PG +GP G  G  G     
Sbjct: 1165 GPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKP 1224

Query: 593  ALQNEPTPA-PEDNGCPPHWKNFT 615
             L+ +P PA P     PP +K  T
Sbjct: 1225 GLRGDPGPAGPPGLMGPPGFKGKT 1248



 Score =  155 bits (393), Expect = 1e-37
 Identities = 78/159 (49%), Positives = 88/159 (55%), Gaps = 14/159 (8%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERG----- 497
            G PG  GP+GD G  GPPG TG  G +GE G  GP G  G  G +GP GPPG+ G     
Sbjct: 1249 GHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGIS 1308

Query: 498  GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557
              G KG +G  G RG  G PG  GP G PGPPG PG +G  G +GPPG QG  G  G  G
Sbjct: 1309 AVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKG 1368

Query: 558  VP---------GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
             P         G +G  G+PG PG  G  GP GPPGP+G
Sbjct: 1369 DPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAG 1407



 Score =  147 bits (371), Expect = 3e-35
 Identities = 82/175 (46%), Positives = 88/175 (50%), Gaps = 15/175 (8%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---PAGPPGERG 497
            L G  G  GP G RGS GPPGP G  G  G  G PG PG  GERG  G     G PG  G
Sbjct: 1028 LPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPG 1087

Query: 498  GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGP------------PG 545
              G  G+ GP G  G  G+ G  G +G+ G PGPPG EGLPGP GP             G
Sbjct: 1088 QPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSG 1147

Query: 546  FQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP 600
             +G QG  G+PG PGP G PG PG  G PGP GP    G  G   P  L   P P
Sbjct: 1148 EKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGP 1202



 Score =  141 bits (356), Expect = 2e-33
 Identities = 84/215 (39%), Positives = 98/215 (45%), Gaps = 55/215 (25%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
            +GPPG +G  G  G +G PG  G KGQ GEKG  G PG  G+ G +GP GPPG  G +G 
Sbjct: 1352 EGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGH 1411

Query: 502  KGSQGPKGSRG------------------------------------------------S 513
             G+ GP GS G                                                +
Sbjct: 1412 PGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA 1471

Query: 514  PGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR-----GLPGLP 568
            PG+PGP G  G PG PG PG  GLPG  G  G QGL G  G PG  G +     G+ G  
Sbjct: 1472 PGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGEN 1531

Query: 569  GVPGMPGPKGPPGPPGPSGAVVPLALQNEP-TPAP 602
            G+PG PGP+GPPG  G  GA  P+  Q  P  P P
Sbjct: 1532 GLPGPPGPQGPPG-YGKMGATGPMGQQGIPGIPGP 1565



 Score =  140 bits (354), Expect = 3e-33
 Identities = 83/187 (44%), Positives = 98/187 (52%), Gaps = 36/187 (19%)

Query: 431 HGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEP--------------G 476
           HG    N T+      P GP+G +G +G PGP G+KG+KG +G                G
Sbjct: 321 HGARDSNVTL-----APSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEG 375

Query: 477 PPGPAGERGPIGPAGPPG---ERGGKGSKGSQGPKGSRGSPGKP---------GPQGPSG 524
           P G  GE G +GP+G PG   E+G KG KG  G KG  G PG+          GP+G  G
Sbjct: 376 PKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKG 435

Query: 525 DPGPPGPPGKEGLPGP---QGPPGFQGLQGTVGEP-GVPGPRGLPGLPGVPGMPGPKGPP 580
           DPG  GP G  G PGP    GPPG  GL GT G+P G PGP+G  G  G+PG  GP G P
Sbjct: 436 DPGFVGPEGLAGEPGPPGLPGPPGI-GLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKP 494

Query: 581 GPPGPSG 587
           G PG  G
Sbjct: 495 GKPGVKG 501



 Score =  140 bits (352), Expect = 6e-33
 Identities = 72/147 (48%), Positives = 80/147 (54%)

Query: 452  GDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSR 511
            GD G  G PG  G  G  G++GE GPPG  G  GP GP GPPG  G  GS G  G +G R
Sbjct: 1012 GDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGER 1071

Query: 512  GSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVP 571
            G  G  G +G  G PG PG PG  G PG  G  G +G  G+ GE G PGP G  GLPG P
Sbjct: 1072 GLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPP 1131

Query: 572  GMPGPKGPPGPPGPSGAVVPLALQNEP 598
            G  GP+G  GP G SG       Q +P
Sbjct: 1132 GPAGPRGERGPQGNSGEKGDQGFQGQP 1158



 Score =  138 bits (347), Expect = 2e-32
 Identities = 80/181 (44%), Positives = 92/181 (50%), Gaps = 26/181 (14%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGE---------------KGEPGPPGPAGERGPI 487
           G PG  G  G  G  G  GP G KG+KG+                G PG PGP GE+GP 
Sbjct: 694 GTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPE 753

Query: 488 GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGP-----QGPSGDPGPPGPPGKEGLPGPQG 542
           G  G PG+ G  G  G QGP G +G  G+PGP     QGP G+PG PG PG +GLPGP+G
Sbjct: 754 G-VGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRG 812

Query: 543 PPGFQGLQGTVGEPGVPGPRGLPGLPGV-----PGMPGPKGPPGPPGPSGAVVPLALQNE 597
           PPG  G +G  G PGV G  G  G PG      PG  G +G  G  G  G   P   + E
Sbjct: 813 PPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGE 872

Query: 598 P 598
           P
Sbjct: 873 P 873



 Score =  138 bits (347), Expect = 2e-32
 Identities = 77/173 (44%), Positives = 84/173 (48%), Gaps = 18/173 (10%)

Query: 449  GPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPK 508
            G  G  GS G PGP G  GQ+GE+G PG  G  G  GPIGP G PG  G  G  G QG +
Sbjct: 1012 GDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGER 1071

Query: 509  GSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLP 568
            G  G  G  G  GP G PG PG  G  GLPG +G  G+ G  G  GEPG PG  GLPG P
Sbjct: 1072 GLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPP 1131

Query: 569  GVPGMPGPKGP------------------PGPPGPSGAVVPLALQNEPTPAPE 603
            G  G  G +GP                  PGPPGP G    +     P P  E
Sbjct: 1132 GPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAE 1184



 Score =  135 bits (339), Expect = 2e-31
 Identities = 80/187 (42%), Positives = 98/187 (52%), Gaps = 26/187 (13%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           G PG +GP G +G QG PGP G +G +G +GEPG PG  G +G  GP GPPG  G KG++
Sbjct: 765 GLPGVQGPPGLKGVQGEPGPPG-RGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQ 823

Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG----- 557
           GS G KG+ G  G PG    +   GPPG  G++G  G +G PG +G +G  GEPG     
Sbjct: 824 GSPGVKGATGPVGPPG----ASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCP 879

Query: 558 ---------VPGPRGL-------PGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601
                    +PG  GL       PG  G PG+PGP GPPG PG  G      L  +P   
Sbjct: 880 SQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLT 939

Query: 602 PEDNGCP 608
            E    P
Sbjct: 940 AELGSLP 946



 Score =  133 bits (335), Expect = 5e-31
 Identities = 82/189 (43%), Positives = 95/189 (50%), Gaps = 30/189 (15%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEP------------------GPPGPAG 482
           L+G  G  G  G  GS GPPGP G  G KG KGEP                    PGP+G
Sbjct: 597 LKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSG 656

Query: 483 ERGPIGPAG--PPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP 540
           E+G  GP G   PG++G  G +G +G KG  G+PG PG  G +G PG  G PG +G  GP
Sbjct: 657 EKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGP 716

Query: 541 QGPPG-----FQGLQGTV----GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
           +G  G        LQGTV    G PG PGP+G  G  GV G PG  G PG PG  G    
Sbjct: 717 KGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGV-GRPGKPGQPGLPGVQGPPGL 775

Query: 592 LALQNEPTP 600
             +Q EP P
Sbjct: 776 KGVQGEPGP 784



 Score =  132 bits (332), Expect = 1e-30
 Identities = 81/203 (39%), Positives = 101/203 (49%), Gaps = 37/203 (18%)

Query: 439 TILQGPPGPRGPRGDRGSQGP-----------PGPTGNKGQKGEKGEPGPPGPA--GERG 485
           T + G PG  GP+G++G +G            PG  G  G KG +GEPGPPG    G +G
Sbjct: 735 TDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQG 794

Query: 486 PIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPP-----GPPGKEGLPGP 540
             G  G PG +G  G +G  GP G +G+ G PG +G +G  GPP     GPPG++G  G 
Sbjct: 795 EPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQ 854

Query: 541 QGPPGFQGLQGTVGEPGVPGPRGLP--------GLPGVPGM-------PGPKGPPGPPGP 585
            G  G  G +G  GE G PG    P        G+PG PG+       PGP+GPPG PGP
Sbjct: 855 TGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGP 914

Query: 586 SGAVVPLALQNEPTPAPEDNGCP 608
            G      LQ      P +NG P
Sbjct: 915 PGPPGVPGLQG----VPGNNGLP 933



 Score =  130 bits (328), Expect = 3e-30
 Identities = 69/144 (47%), Positives = 77/144 (53%), Gaps = 2/144 (1%)

Query: 443  GPPGPRGPRGDRGSQGPPG--PTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
            GPPG  GP G  G  GP G    G KG +G  GE G  G  G+ GP G  GPPGE G  G
Sbjct: 1288 GPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDG 1347

Query: 501  SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPG 560
            + G +GP G +G  G PGP+G  G  G  G  G++G  G  G PG  G  G VG PG  G
Sbjct: 1348 AAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAG 1407

Query: 561  PRGLPGLPGVPGMPGPKGPPGPPG 584
             RG PG PG  G PG  G PG  G
Sbjct: 1408 ERGHPGAPGPSGSPGLPGVPGSMG 1431



 Score =  129 bits (325), Expect = 8e-30
 Identities = 74/172 (43%), Positives = 92/172 (53%), Gaps = 18/172 (10%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP---------IGPAG 491
           +QG PGP G RG +G QG PG  G  G +G  G  GPPGP GE+G           GP G
Sbjct: 778 VQGEPGPPG-RGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVG 836

Query: 492 PPGE--RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGK-----EGLPGPQGP- 543
           PPG    G  G  G QG  G RG+PG+ GP+G  G+PG    P +      G+PG  G  
Sbjct: 837 PPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLW 896

Query: 544 PGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQ 595
            G     G  G PG+PGP G PG+PG+ G+PG  G PG PG +  +  L ++
Sbjct: 897 MGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIE 948



 Score =  129 bits (323), Expect = 1e-29
 Identities = 83/210 (39%), Positives = 96/210 (45%), Gaps = 58/210 (27%)

Query: 449 GPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPK 508
           GP+G +G  G  GP G  G+ G  G PGPPG      P  P GPPG +G KGS G  G +
Sbjct: 429 GPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKE 488

Query: 509 GSRGSPGKPGPQGPSGDP------------------GPPGPPGKEGLPGP-QGPPGFQGL 549
           G  G PGKPG +G  GDP                  G PGP G+ G P P +G PG QG+
Sbjct: 489 GPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGI 548

Query: 550 QGTVGEP-----------------------GVPGPRGLPGLPGVPGMPGPK--------- 577
           +G  GEP                       G PG  GLPGLPG  G+PG K         
Sbjct: 549 KGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPG-FGLPGLPGRAGVPGLKGEKGNFGEA 607

Query: 578 GPPGPPGPSGAVVPLALQN------EPTPA 601
           GP G PGP G V P  ++       EP PA
Sbjct: 608 GPAGSPGPPGPVGPAGIKGAKGEPCEPCPA 637



 Score =  124 bits (312), Expect = 2e-28
 Identities = 78/215 (36%), Positives = 84/215 (39%), Gaps = 68/215 (31%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
            L G PGP G  G  G  G  G  G +G  G++G  GPPGP G+ G  G  G  GE+G  G
Sbjct: 1327 LPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAG 1386

Query: 501  SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPG--------------------- 539
              G  G  GS G  G PGP G  G PG PGP G  GLPG                     
Sbjct: 1387 MPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQE 1446

Query: 540  ------------------------PQGPPGFQGLQGTVGEPGVPGPRGLP---------G 566
                                      G PG  G  G  G PG PG  GLP         G
Sbjct: 1447 IIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQG 1506

Query: 567  LPGVPGMPGPKGP--------------PGPPGPSG 587
            LPGV G+PG KG               PGPPGP G
Sbjct: 1507 LPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQG 1541



 Score =  123 bits (309), Expect = 5e-28
 Identities = 77/194 (39%), Positives = 86/194 (44%), Gaps = 51/194 (26%)

Query: 445  PGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI----------------G 488
            PGP+GP G  G  GPPG  G +G  G  G PG PG   E G +                G
Sbjct: 903  PGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQG 962

Query: 489  PAGPPG---ERGGKGSKG-----------------------------SQGPKGSRGSPGK 516
                PG   E+G KG +G                             S+G  G  GSPG 
Sbjct: 963  QRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGL 1022

Query: 517  PGPQGPSGDPGPPGPPGKEGLPGPQ---GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGM 573
            PGP G  G  G  GPPG  G PGP    GPPGF G  G+ G PG+ G RGL GL G  G 
Sbjct: 1023 PGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGE 1082

Query: 574  PGPKGPPGPPGPSG 587
            PGP G PG PG +G
Sbjct: 1083 PGPPGQPGYPGATG 1096



 Score =  123 bits (308), Expect = 7e-28
 Identities = 76/173 (43%), Positives = 84/173 (48%), Gaps = 14/173 (8%)

Query: 449 GPRGDRGSQG-----PPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKG 503
           G  GD GS G      PG  G  G KGEKG  G  GPAG  GP GP GP G +G KG   
Sbjct: 573 GASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPC 632

Query: 504 SQGPKGSRGSPGK------PGPQGPSGDPGPP--GPPGKEGLPGPQGPPGFQGLQGTVGE 555
              P  S    G       PGP G  G+PGPP  G PGK+G  G +G  G +G  G  G+
Sbjct: 633 EPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGD 692

Query: 556 PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
           PG PG  G PGL G PG+ GP GP G  G      P +LQ   T      G P
Sbjct: 693 PGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACP-SLQGTVTDMAGRPGQP 744



 Score =  123 bits (308), Expect = 7e-28
 Identities = 88/239 (36%), Positives = 100/239 (41%), Gaps = 93/239 (38%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG------PA------ 490
           G PG  G  G  G +G  G  G  G  G  G PGP GPAG +G  G      PA      
Sbjct: 584 GLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQD 643

Query: 491 ------------------GPP-----------GERGGKGSKGSQGPKGSRGSP------- 514
                             GPP           GERG KG KG  G  G  G+P       
Sbjct: 644 GDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPG 703

Query: 515 --GKPGPQGPS---------------------------GDPGP-----------PGPPGK 534
             G+PG QGP+                           G PGP           PG PG+
Sbjct: 704 LSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQ 763

Query: 535 EGLPGPQGPPGFQGLQGTVGEP--GVPGPR---GLPGLPGVPGMPGPKGPPGPPGPSGA 588
            GLPG QGPPG +G+QG  G P  GV GP+   G PGLPG+ G+PGP+GPPGP G  GA
Sbjct: 764 PGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGA 822



 Score =  122 bits (307), Expect = 9e-28
 Identities = 82/230 (35%), Positives = 93/230 (40%), Gaps = 84/230 (36%)

Query: 442  QGPPG---PRGPRGDRGSQGPPGPTG---------------------------------- 464
            QGPPG   P GP G  G QG PG  G                                  
Sbjct: 906  QGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRA 965

Query: 465  ------NKGQKGEKGEPGPPG-----------------------PAGERGPIGPAGPPGE 495
                   KG+KG++G PG PG                         G+ G +G  G PG 
Sbjct: 966  HPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGP 1025

Query: 496  RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL---------------PGP 540
             G  G +G +GP G RGSPG PGP GP G PG  G PG  GL               PGP
Sbjct: 1026 PGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGP 1085

Query: 541  QGPPGFQGLQGTVGEPGVPGPRGLPGL---PGVPGMPGPKGPPGPPGPSG 587
             G PG+ G  G  G PG+ G RG  G     G PG PG +G PGPPGP+G
Sbjct: 1086 PGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAG 1135



 Score =  110 bits (276), Expect = 4e-24
 Identities = 72/177 (40%), Positives = 82/177 (46%), Gaps = 31/177 (17%)

Query: 444 PPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP-------IGPAGP---- 492
           PP   G R    +  P GP   KG KGE+G PGPPG  GE+G        I P  P    
Sbjct: 317 PPCVHGARDSNVTLAPSGP---KGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCA 373

Query: 493 PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552
            G +G KG  G+ GP G  GS G+ G +G  GD G  G PGK G  G  G     G +G 
Sbjct: 374 EGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQ 433

Query: 553 VGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609
            G+PG  GP GL G PG         PPG PGP G  +P          P D G PP
Sbjct: 434 KGDPGFVGPEGLAGEPG---------PPGLPGPPGIGLP--------GTPGDPGGPP 473



 Score = 88.6 bits (218), Expect = 2e-17
 Identities = 57/133 (42%), Positives = 63/133 (47%), Gaps = 7/133 (5%)

Query: 455  GSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP---PGERGGKGSKGSQGPKGSR 511
            G  GPPG  G  G+ G  G PG PG  G  G  G  G    PG +G KG  G  G  G  
Sbjct: 1473 GRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGI-GIAGEN 1531

Query: 512  GSPGKPGPQGPS--GDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRG-LPGLP 568
            G PG PGPQGP   G  G  GP G++G+PG  GPPG  G  G  G        G +P   
Sbjct: 1532 GLPGPPGPQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQ 1591

Query: 569  GVPGMPGPKGPPG 581
              P M   KGP G
Sbjct: 1592 QYPPMKTMKGPFG 1604



 Score = 83.6 bits (205), Expect = 6e-16
 Identities = 51/129 (39%), Positives = 63/129 (48%), Gaps = 17/129 (13%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPA--------G 491
            GPPG  G  G  G+ G PG  G  G++G +G PG    PG  GE+G IG          G
Sbjct: 1476 GPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPG 1535

Query: 492  PPGERG--GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKE----GLPGPQGPPG 545
            PPG +G  G G  G+ GP G +G PG PGP GP G PG  G          +P  Q  P 
Sbjct: 1536 PPGPQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPP 1595

Query: 546  FQGLQGTVG 554
             + ++G  G
Sbjct: 1596 MKTMKGPFG 1604



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 33/76 (43%), Positives = 38/76 (50%), Gaps = 11/76 (14%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP-------P 493
            L GPPGP+GP G     G  G TG  GQ+G  G PGPPGP G+ G  G   P       P
Sbjct: 1533 LPGPPGPQGPPG----YGKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMP 1588

Query: 494  GERGGKGSKGSQGPKG 509
             E+     K  +GP G
Sbjct: 1589 MEQQYPPMKTMKGPFG 1604


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  172 bits (435), Expect = 1e-42
 Identities = 83/158 (52%), Positives = 94/158 (59%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            G PGP GP G RG  GP GP G +G+KG KGE G  GP G+ GPIGP G PG+ G  G +
Sbjct: 1381 GEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLR 1440

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
            G  GP G +G PG PGP GP G  GPPG PG +G  GP+G  G  GL G +G PG  G +
Sbjct: 1441 GIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEK 1500

Query: 563  GLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP 600
            G  GLPG  G  GPKG  G  GPSG + P      P P
Sbjct: 1501 GDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGP 1538



 Score =  169 bits (429), Expect = 7e-42
 Identities = 86/174 (49%), Positives = 97/174 (55%), Gaps = 27/174 (15%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI---GPAGPPGERG 497
            L G  GP GP+G+RG +G  GP+G  G  G KG PG  GP G  GP+   G  GPPGE G
Sbjct: 1295 LPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPG 1354

Query: 498  GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGE-- 555
              G  G  G KG  G PG+ G  GP+G+PGP GPPGK G PGP GP G QG +G  GE  
Sbjct: 1355 PAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAG 1414

Query: 556  ----------------PGVPGPRGLPGLP------GVPGMPGPKGPPGPPGPSG 587
                            PG PGP GL G+P      G+PG PGP GPPGP GP G
Sbjct: 1415 LEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPG 1468



 Score =  169 bits (427), Expect = 1e-41
 Identities = 93/211 (44%), Positives = 103/211 (48%), Gaps = 48/211 (22%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP------PG 494
            L GP GP GP G+ G +G  G  G KG KG+KGE GPPGP G +GPIG  GP      PG
Sbjct: 1142 LPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPG 1201

Query: 495  ERGGKGSKGSQGPKGSRGSPGKPGP---------------------QGPSGDPGPPGPPG 533
             RG +G  G +G +G RG PG PGP                      GP G PGP GP G
Sbjct: 1202 PRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSG 1261

Query: 534  KEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLP---------------------GVPG 572
              G  GPQGPPG  G  G VGE G PG  G PGLP                     G  G
Sbjct: 1262 APGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAG 1321

Query: 573  MPGPKGPPGPPGPSGAVVPLALQNEPTPAPE 603
             PGPKGPPG  GP G+  P+    +P P  E
Sbjct: 1322 PPGPKGPPGDDGPKGSPGPVGFPGDPGPPGE 1352



 Score =  166 bits (419), Expect = 9e-41
 Identities = 91/203 (44%), Positives = 103/203 (50%), Gaps = 45/203 (22%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP---------- 492
            GP G RGP G RG +GP G TG  G KG  G  GP GP GERGP GP GP          
Sbjct: 907  GPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPP 966

Query: 493  --------PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD---------PGPPGPPGKE 535
                    PG  G +G  G QG  G  G PG  GPQGP+G+         PGPPGPPG++
Sbjct: 967  GPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQ 1026

Query: 536  GLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGP---------KGPPGPP--- 583
            GLPG  G  G +G  G  G PG  GP GL G PG  G+PGP         +GPPGPP   
Sbjct: 1027 GLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPA 1086

Query: 584  ------GPSGAVVPLALQNEPTP 600
                  GP+GA  P+ +   P P
Sbjct: 1087 GSPGERGPAGAAGPIGIPGRPGP 1109



 Score =  165 bits (417), Expect = 2e-40
 Identities = 83/151 (54%), Positives = 94/151 (62%), Gaps = 3/151 (1%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPA---GERGPIGPAGPPGERG 497
            L G  GP G RG  G +G PGP G  G KG +G PGPPGPA   GERGP G AGP G  G
Sbjct: 1046 LPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPG 1105

Query: 498  GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557
              G +G  GP G +G+PG+ GPQGP+G  G  GP G  G  GP GPPG  G +G +GEPG
Sbjct: 1106 RPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPG 1165

Query: 558  VPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588
              G +G  G  G PG  GP+GP G PGPSGA
Sbjct: 1166 QKGSKGDKGEQGPPGPTGPQGPIGQPGPSGA 1196



 Score =  165 bits (417), Expect = 2e-40
 Identities = 92/182 (50%), Positives = 99/182 (54%), Gaps = 36/182 (19%)

Query: 443  GPPGPRGPRGDRGS---------------QGPPGPTGNKGQKGEKGEPGPPG------PA 481
            GPPGP G  G+RG                QGPPGP G KG  GEKG  GP G      P 
Sbjct: 1081 GPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPV 1140

Query: 482  GERGPIGPAGPPGERGGKGS------KGSQGPKGSRGSPGKPGPQGPSGDPGP------P 529
            G  GP GP GPPGE G KG       KGS+G KG +G PG  GPQGP G PGP      P
Sbjct: 1141 GLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEP 1200

Query: 530  GPPGKEGL---PGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPS 586
            GP G++GL    G +GP GF G  G VG  G+PGP G  G  G  G  GP GPPGP GPS
Sbjct: 1201 GPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPS 1260

Query: 587  GA 588
            GA
Sbjct: 1261 GA 1262



 Score =  164 bits (416), Expect = 2e-40
 Identities = 90/197 (45%), Positives = 101/197 (51%), Gaps = 34/197 (17%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---------------------PGPA 481
            GPPGP+GP GD G +G PGP G  G  G  GEPGP                     PGP 
Sbjct: 1321 GPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPT 1380

Query: 482  GERGPIGPAG------PPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKE 535
            GE GP GP G      P G  G +G KG++G  G  G PGK GP GP G PG PGP G  
Sbjct: 1381 GEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLR 1440

Query: 536  GLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQ 595
            G+PGP G    QGL G+ G  G PGP G PGLPG+ G  GPKG  G PG  G + P   Q
Sbjct: 1441 GIPGPVGE---QGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQ 1497

Query: 596  NEP----TPAPEDNGCP 608
             E      P P+ +  P
Sbjct: 1498 GEKGDRGLPGPQGSSGP 1514



 Score =  163 bits (413), Expect = 5e-40
 Identities = 84/163 (51%), Positives = 96/163 (58%), Gaps = 15/163 (9%)

Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE------PGPPGPAGERGPIGP 489
           + F  L G PG +G RGD G  GPPGP G+ G++G+ GE      PG PGP G  GP GP
Sbjct: 630 RGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGP 689

Query: 490 AGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQ---GPPGF 546
            GPPG  G  G  G  GPKG+ G  G+PGP      PG  G PG +GLPGPQ   GPPG 
Sbjct: 690 PGPPGPPGVTGMDGQPGPKGNVGPQGEPGP------PGQQGNPGAQGLPGPQGAIGPPGE 743

Query: 547 QGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAV 589
           +G  G  G PG+PG  G PG PG  G PG KG  GPPGP G +
Sbjct: 744 KGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPI 786



 Score =  163 bits (412), Expect = 6e-40
 Identities = 88/187 (47%), Positives = 99/187 (52%), Gaps = 27/187 (14%)

Query: 441 LQGPPGP------RGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG 494
           +QGPPGP      RG  G  G++G PG TG KG +G  G  G PG  G RG  GP+GPPG
Sbjct: 596 VQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPG 655

Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQG---PSGDPGPPGPPGKEGL-------------- 537
             G  G +G  G  G RG PG+PGP+G   P G PGPPGPPG  G+              
Sbjct: 656 PPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQG 715

Query: 538 ----PGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLA 593
               PG QG PG QGL G  G  G PG +G  G PG+PGMPG  GPPG PG  G      
Sbjct: 716 EPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKG 775

Query: 594 LQNEPTP 600
            Q  P P
Sbjct: 776 GQGPPGP 782



 Score =  162 bits (411), Expect = 8e-40
 Identities = 87/174 (50%), Positives = 98/174 (56%), Gaps = 18/174 (10%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            GP G  GP GD+G  G PG TG+ G  GE   PGP GP G+RGP GPAGP G +G KG+K
Sbjct: 1354 GPAGQDGPPGDKGDDGEPGQTGSPGPTGE---PGPSGPPGKRGPPGPAGPEGRQGEKGAK 1410

Query: 503  GSQG---------PKGSRGSPGKPGPQGPSGDPGP------PGPPGKEGLPGPQGPPGFQ 547
            G  G         P G +G+PGKPGP G  G PGP      PG PG +G PGP GPPG  
Sbjct: 1411 GEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLP 1470

Query: 548  GLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601
            GL+G  G  G  G  GL GL G PG  G KG  G PGP G+  P   Q    P+
Sbjct: 1471 GLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPS 1524



 Score =  160 bits (404), Expect = 5e-39
 Identities = 84/177 (47%), Positives = 99/177 (55%), Gaps = 11/177 (6%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE---PGPPGPAGERGPIGPAGPPGERGGK 499
            G PGP GP G++G  G PG  G  G++G KG    PG PG  GE+G  G  G PG RG +
Sbjct: 853  GDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQR 912

Query: 500  GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559
            G  G +G +G RG  GKPGP+G SG  GP GPPG+ G  GPQGP GF G +G  G PG  
Sbjct: 913  GPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKD 972

Query: 560  GPRGLPGLPGVPGMPGPKGPPGPP------GPSGAVVPLALQNEPTP--APEDNGCP 608
            G  G PG  G  G  G  GPPGPP      GP+G   P+  +  P P   P + G P
Sbjct: 973  GLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLP 1029



 Score =  159 bits (403), Expect = 7e-39
 Identities = 83/170 (48%), Positives = 96/170 (56%), Gaps = 4/170 (2%)

Query: 442  QGP---PGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498
            QGP   PGP+GP G  G  G PG  G +G+ G +G+ GPPGP G  GP GP G  G  G 
Sbjct: 954  QGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGE 1013

Query: 499  KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV 558
            +G  G  GP G +G PG  G +G  GDPGP G PGK+G PG +G PG +GL G VG  G+
Sbjct: 1014 RGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGL 1073

Query: 559  PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
             G  G PG PG  G PG +GP G  GP G       Q  P PA E  G P
Sbjct: 1074 KGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGE-KGAP 1122



 Score =  159 bits (401), Expect = 1e-38
 Identities = 85/171 (49%), Positives = 98/171 (57%), Gaps = 16/171 (9%)

Query: 446 GPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQ 505
           GP GP G  G  GP GP G+ G KGE G+ GP GP G +GP GPAG PG RG  GS G+ 
Sbjct: 559 GPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGA- 617

Query: 506 GPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL---PGPQGPPGFQGLQGTVGEPGVPGPR 562
                RG PG+ GP+G  G  G  G PG++G    PGP GPPG  G  G  G+ G  GPR
Sbjct: 618 -----RGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPR 672

Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP----APEDNGCPP 609
           GLPG PG  G+ GPKGPPGPPGP G      +  +P P     P+    PP
Sbjct: 673 GLPGEPGPRGLLGPKGPPGPPGPPGVT---GMDGQPGPKGNVGPQGEPGPP 720



 Score =  157 bits (396), Expect = 4e-38
 Identities = 90/198 (45%), Positives = 98/198 (49%), Gaps = 34/198 (17%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP------PGPAGERGPIGPAGPPG 494
            L G PG +GP+G  G  G PG  G KG +G  G+PGP       GP GERGP G  G PG
Sbjct: 872  LPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPG 931

Query: 495  ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLP---------------G 539
             +G  G  G  GP G RG  G  GP G  G  GPPGPPGK+GLP               G
Sbjct: 932  PKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 991

Query: 540  PQGPPGFQGLQGTVGE---------PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVV 590
            P GPPG  G QG  GE         PG PGP G  GLPG+ G  G KG PGP G  G   
Sbjct: 992  PPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDG 1051

Query: 591  PLALQNEPTPAPEDNGCP 608
            P  L+      P D G P
Sbjct: 1052 PPGLRG----FPGDRGLP 1065



 Score =  154 bits (390), Expect = 2e-37
 Identities = 82/177 (46%), Positives = 90/177 (50%), Gaps = 6/177 (3%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI------GPAGPPGE 495
            +GP G  GP G  G QG PGP G KG+ G+ G+ GPPGP G RGP       GP GPPG 
Sbjct: 1215 EGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGG 1274

Query: 496  RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGE 555
             G  G+ G +G  G  G PG PG  GP G  G  G  G+ G  G  GPPG +G  G  G 
Sbjct: 1275 IGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGP 1334

Query: 556  PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPPHWK 612
             G PGP G PG PG PG PGP G  GPPG  G          P P  E     P  K
Sbjct: 1335 KGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGK 1391



 Score =  154 bits (390), Expect = 2e-37
 Identities = 84/169 (49%), Positives = 95/169 (56%), Gaps = 10/169 (5%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKG---QKGEKGEPGPPGPAGERGPIGPAGPPGERG 497
            L+GPPG  GP G +G+ G PGP G +G     GE+G PG PGP G  GP+GP G PG +G
Sbjct: 1415 LEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKG 1474

Query: 498  GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557
              G KG +G  G  G  G PG QG  GD G PGP G  G  G QG  G  G  G  G PG
Sbjct: 1475 DSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPG 1534

Query: 558  VPGPRGLPGLPGVPGMPGPK------GPPGPPGPSGAVV-PLALQNEPT 599
            +PGP G  G  G  G  GPK      GPPGPPGP G V+ PL +Q   T
Sbjct: 1535 LPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLPIQASRT 1583



 Score =  154 bits (388), Expect = 4e-37
 Identities = 86/181 (47%), Positives = 97/181 (53%), Gaps = 24/181 (13%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
            L GP G  G +G+ G  GPPGP G+ G++G  G  GP G  G  GP GP GP GE+G  G
Sbjct: 1064 LPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPG 1123

Query: 501  SKGSQGPKGS---RGSPGKPGPQGPSGDP---------GPPGPPGKEGLPGPQGPPGFQG 548
             KG QGP G    +G  G PGP GP G P         G PG  G +G  G QGPPG  G
Sbjct: 1124 EKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTG 1183

Query: 549  LQGTVGEP------GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAP 602
             QG +G+P      G PGPRG  GL G  G  GP+G PGPPGP G      LQ  P P  
Sbjct: 1184 PQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVG------LQGLPGPPG 1237

Query: 603  E 603
            E
Sbjct: 1238 E 1238



 Score =  153 bits (387), Expect = 5e-37
 Identities = 79/160 (49%), Positives = 92/160 (57%), Gaps = 9/160 (5%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGE------KGEPGPPGPAGERGPIGPAGPPG 494
           L+G PG  GP+G RG QGPPGP G  G++G       +G PG  GP G+RG  G AG PG
Sbjct: 581 LKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPG 640

Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVG 554
           E+G +G  G  GP G  G  G+ G  G  G  G PG PG  GL GP+GPPG  G  G  G
Sbjct: 641 EKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTG 700

Query: 555 EPGVPGPRGLPGLPGVPGMPGPKGPPGP---PGPSGAVVP 591
             G PGP+G  G  G PG PG +G PG    PGP GA+ P
Sbjct: 701 MDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGP 740



 Score =  153 bits (386), Expect = 6e-37
 Identities = 82/179 (45%), Positives = 99/179 (55%), Gaps = 12/179 (6%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGN------KGQKGEKGEPGPPGPAGERGPIGPAGPPGER 496
           G PG  GP G++G QGPPGP G       +G KG  G  G  G  GE+G  G  G  G+ 
Sbjct: 763 GHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDM 822

Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQG---PSGDPGPPGPPGKEG---LPGPQGPPGFQGLQ 550
           G KG +G  GP G RG  G  GP+G   P+GDPGP GPPG++G   +PG  G PG QG +
Sbjct: 823 GIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPK 882

Query: 551 GTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609
           G++G PG PG  G  G  G PG PGP+G  GP GP G   P  +  +P P     G  P
Sbjct: 883 GSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGP 941



 Score =  153 bits (386), Expect = 6e-37
 Identities = 88/199 (44%), Positives = 104/199 (52%), Gaps = 39/199 (19%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKG------QKGEKGEPGPPGPAGERGPIGPAGPPGE 495
            QGP G  GP G+RG  GPPGP G +G      ++G KG+PGP G  G+ GP G  G PG+
Sbjct: 1002 QGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGD 1061

Query: 496  RGGKGSKGSQGPKGSRGSPGKPGPQGPSGD------------------PGPPGPPGKEGL 537
            RG  G  G+ G KG+ G PG PGP G  G+                   GPPGP G++G 
Sbjct: 1062 RGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGA 1121

Query: 538  PG---PQGPPGFQGLQGTVGEPGVPGPRGLP---------GLPGVPGMPGPKGPPGPPGP 585
            PG   PQGP G  GLQG VG PG  GP G P         G PG  G  G KG  GPPGP
Sbjct: 1122 PGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGP 1181

Query: 586  SGAVVPLALQNEPTPAPED 604
            +G   P+    +P P+  D
Sbjct: 1182 TGPQGPI---GQPGPSGAD 1197



 Score =  153 bits (386), Expect = 6e-37
 Identities = 79/159 (49%), Positives = 86/159 (54%), Gaps = 12/159 (7%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG---ERGPIGPAGPPGERG 497
            L GPPG +G  GD G  GPPGP G +G  G  G  GP GP G     G +G  G PGE G
Sbjct: 1232 LPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAG 1291

Query: 498  GKGSKGS---QGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVG 554
              G  G     GPKG RG  G+ GP G +G PGP GPPG +G  G  GP GF G  G  G
Sbjct: 1292 EPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPG 1351

Query: 555  EP------GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
            EP      G PG +G  G PG  G PGP G PGP GP G
Sbjct: 1352 EPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPG 1390



 Score =  152 bits (384), Expect = 1e-36
 Identities = 82/175 (46%), Positives = 95/175 (54%), Gaps = 10/175 (5%)

Query: 443  GPPGPRGPRG---------DRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPP 493
            G PGPRG +G          RG  GPPGP G +G  G  GE G  G  G+ GP GP GP 
Sbjct: 1198 GEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPR 1257

Query: 494  GERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553
            G  G  G+ G QGP G  G+PG  G +G  G+ G PG PG+ G PGP+G  G +G  G  
Sbjct: 1258 GPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPS 1317

Query: 554  GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
            G  G PGP+G PG  G  G PGP G PG PGP G   P A Q+ P     D+G P
Sbjct: 1318 GAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGP-AGQDGPPGDKGDDGEP 1371



 Score =  150 bits (379), Expect = 4e-36
 Identities = 83/173 (47%), Positives = 93/173 (53%), Gaps = 24/173 (13%)

Query: 439  TILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPP---------GPAGERGPIGP 489
            T  QG  GP GP G  G QGP G TG  G++G  G PGPP         G  G +G  GP
Sbjct: 984  TGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGP 1043

Query: 490  A------GPPGERGGKGSKGSQGPKGS---RGSPGKPGPQGPSGDPGPPGPPGK------ 534
            A      GPPG RG  G +G  GP G+   +G+ G PGP GP+G PG  GP G       
Sbjct: 1044 AGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGI 1103

Query: 535  EGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
             G PGPQGPPG  G +G  GE G  GP G  GL G  G+PGP GP GPPG  G
Sbjct: 1104 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDG 1156



 Score =  149 bits (376), Expect = 9e-36
 Identities = 85/186 (45%), Positives = 96/186 (51%), Gaps = 23/186 (12%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGP---------TGNKGQKGEKGEPGPPGPAGERGPIGPAG 491
            L G PG RG  G +G  GPPGP         TG  G  GE+G PGPPGP GE+G  G AG
Sbjct: 974  LPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAG 1033

Query: 492  PPGERGGKGSKG---SQGPKGSRGSPGKPGPQGP------SGDPGPPGPPGKEGLPGPQG 542
              G +G  G  G     GP G RG PG  G  GP       G+ GPPGPPG  G PG +G
Sbjct: 1034 KEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERG 1093

Query: 543  PPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNE--PTP 600
            P    G  G +G PG PGP+G PG  G  G PG KGP GP G  G   P+ L     P  
Sbjct: 1094 P---AGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVG 1150

Query: 601  APEDNG 606
             P ++G
Sbjct: 1151 PPGEDG 1156



 Score =  115 bits (288), Expect = 1e-25
 Identities = 89/250 (35%), Positives = 98/250 (39%), Gaps = 95/250 (38%)

Query: 446 GPRGPRG-DRGSQGPPGPTGNKGQKGE----------KGEPGP------PGPAGERGPIG 488
           GP  P   D   +G  GP G KGQKGE          +G PGP      PGP G  GP G
Sbjct: 431 GPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTG 490

Query: 489 PAGPPGER----------------------------GGKGSKGS---------------- 504
             G PGER                            GG G  GS                
Sbjct: 491 QVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAIL 550

Query: 505 -------QGPKGSRGSPGKPGPQGP---------SGDPGPPGPPGKEGLPGPQGPPGFQG 548
                  +GP G  G  G+PGP GP          GD GP GP G +G PGP G PG +G
Sbjct: 551 QQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRG 610

Query: 549 LQGTVGEPGVP------GPRGLPGLPGVPGM------PGPKGPPGPP------GPSGAVV 590
             G+ G  G+P      G RG  GL G+PG       PGP GPPGPP      G  G V 
Sbjct: 611 RAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVG 670

Query: 591 PLALQNEPTP 600
           P  L  EP P
Sbjct: 671 PRGLPGEPGP 680



 Score = 80.9 bits (198), Expect = 4e-15
 Identities = 45/100 (45%), Positives = 52/100 (52%), Gaps = 6/100 (6%)

Query: 480 PAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSG-DPGPPGPPGKEGLP 538
           P      IGP  P  +      +G  GP+G +G  G+P    P     GPPGP G  GLP
Sbjct: 423 PTSSPSEIGPGMPANQ--DTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLP 480

Query: 539 GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKG 578
           GP   PG  G  G VG+PG  GP G PGLPG  G+PGP G
Sbjct: 481 GP---PGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPG 517


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  171 bits (432), Expect = 3e-42
 Identities = 82/145 (56%), Positives = 88/145 (60%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           GPPGP G  G  G  G PG  G +G  GEKGE GPPG AG  G  GPAGPPG +G KG +
Sbjct: 804 GPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGER 863

Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
           GS G  G+ G PG  G  GP G  G PGPPG  G PG  GPPG  G  G  G PGV GP+
Sbjct: 864 GSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPK 923

Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSG 587
           G  G PG  G PG +GPPG PGP G
Sbjct: 924 GDAGQPGEKGSPGAQGPPGAPGPLG 948



 Score =  168 bits (426), Expect = 1e-41
 Identities = 82/151 (54%), Positives = 90/151 (59%), Gaps = 6/151 (3%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKG------EPGPPGPAGERGPIGPAGPPGER 496
           GP GPRG  G+ G  G PG  G +G  G  G      +PGPPG  GE G  GP GP G R
Sbjct: 513 GPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPR 572

Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
           G  G  G  GPKG+ G+PGK G +G  G PGP GPPGK G  GPQGPPG  G  G  G+ 
Sbjct: 573 GQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDT 632

Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           G PGP+GL GLPG  G PG  G PG PGP G
Sbjct: 633 GPPGPQGLQGLPGTGGPPGENGKPGEPGPKG 663



 Score =  165 bits (417), Expect = 2e-40
 Identities = 82/155 (52%), Positives = 90/155 (58%), Gaps = 9/155 (5%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
           QGPPGP GP GD+G  GPPGP G +G  G  G PG  G  GE GP G AG PG  GGKG 
Sbjct: 617 QGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGD 676

Query: 502 KGSQGPKGS---------RGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552
            G+ G +G          RG  G PGP+G  G  GPPGPPG  G PG QG PG +G  G+
Sbjct: 677 AGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGS 736

Query: 553 VGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
            G  G  G  G PG  GVPG  GP+GP GP GP G
Sbjct: 737 PGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPG 771



 Score =  163 bits (413), Expect = 5e-40
 Identities = 90/183 (49%), Positives = 98/183 (53%), Gaps = 17/183 (9%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE------PGPPGPAGERGPIGPAGPPGER 496
           GPPGP GPRG  G  G PGP GN G  G+ GE      PGP GP G+ G  GP GPPG  
Sbjct: 564 GPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPT 623

Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
           G  G KG  GP G +G  G PG  GP G+ G PG PG +G  G  G PG +G  G  GE 
Sbjct: 624 GPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGER 683

Query: 557 GVPGPRGLPGLPGVPGMPGP---KGPPGPPGPSGAVVPLALQNEP-------TPAPE-DN 605
           G PG  G PGL G  G PGP   KG  GPPGP GA     LQ  P       +P P+ D 
Sbjct: 684 GPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDK 743

Query: 606 GCP 608
           G P
Sbjct: 744 GEP 746



 Score =  162 bits (409), Expect = 1e-39
 Identities = 82/152 (53%), Positives = 88/152 (57%), Gaps = 12/152 (7%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG------ERGPIGPAGPPGER 496
           G PG  GPRG  G  GPPGP G  G KGE G PG PG AG      ERG  GP GP G  
Sbjct: 753 GVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFP 812

Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
           G  G  G  G KG RG+PG+ G  GP G  GPPG  G      P GPPG QG++G  G P
Sbjct: 813 GAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSG------PAGPPGPQGVKGERGSP 866

Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588
           G PG  G PG  G+PG PG  G PGPPGPSG+
Sbjct: 867 GGPGAAGFPGARGLPGPPGSNGNPGPPGPSGS 898



 Score =  158 bits (400), Expect = 2e-38
 Identities = 80/155 (51%), Positives = 91/155 (58%), Gaps = 12/155 (7%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           G PGP+GP G  G  GP GP G  G  G+KG+ GPPGP G +G  G  GPPGE G     
Sbjct: 600 GGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENG---KP 656

Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQG---PPGFQGLQGTVGEPGVP 559
           G  GPKG  G+PG PG +G +G PG  GPPG  G PG +G   PPG +G +G  G PG P
Sbjct: 657 GEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPP 716

Query: 560 GPRGLPGLPGVPG------MPGPKGPPGPPGPSGA 588
           G  G PGL G+PG       PGPKG  G PG  GA
Sbjct: 717 GAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGA 751



 Score =  158 bits (399), Expect = 2e-38
 Identities = 83/164 (50%), Positives = 92/164 (56%), Gaps = 15/164 (9%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP------PGPAGER------GPIGPA 490
           G PGP G +G+ G  GPPGP+G +GQ G  G PGP      PG  GER      GP GP 
Sbjct: 549 GKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPP 608

Query: 491 GPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDP---GPPGPPGKEGLPGPQGPPGFQ 547
           G  GE G +G  G  GP G +G  G PGPQG  G P   GPPG  GK G PGP+G  G  
Sbjct: 609 GKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAP 668

Query: 548 GLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
           G  G  G+ G PG RG PGL G PG+ G  GPPGP G  GA  P
Sbjct: 669 GAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGP 712



 Score =  157 bits (398), Expect = 3e-38
 Identities = 83/170 (48%), Positives = 93/170 (54%), Gaps = 27/170 (15%)

Query: 443  GPPGPRGPRGDRGSQG---------PPGPTGNKGQKGEKGEPGP------PGPAGERGPI 487
            G PG +G RG+ GS G         PPGP G  G+ G++GE GP      PGPAG RG  
Sbjct: 1026 GSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAP 1085

Query: 488  GPAGPPGERGGKGSKGSQGPKGSR------GSPGKPGPQGPSGDPGPPGPPGKEGLPGPQ 541
            GP GP G++G  G +G+ G KG R      G+PG PGP G  G  G PGP G  G  GP 
Sbjct: 1086 GPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPS 1145

Query: 542  GPPGFQGLQGTVGEPGVPGP------RGLPGLPGVPGMPGPKGPPGPPGP 585
            GPPG  G  G  G  G PGP      RG  G PG PG PGP GPPG PGP
Sbjct: 1146 GPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGP 1195



 Score =  155 bits (392), Expect = 1e-37
 Identities = 80/172 (46%), Positives = 92/172 (53%), Gaps = 27/172 (15%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKG------EKGEPGPPGPAGERGPIGPAGPPGER 496
            GPPGP+G +G+RGS G PG  G  G +G        G PGPPGP+G  G  GP GP G  
Sbjct: 852  GPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNT 911

Query: 497  GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP------------PGKEGLPGPQGPP 544
            G  GS G  GPKG  G PG+ G  G  G PG PGP             G  G+PGP+G P
Sbjct: 912  GAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSP 971

Query: 545  GFQGLQGTVGEPGV---------PGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
            G QG++G  G+PG          PGP+GLPGL G  G PG  G PG  G  G
Sbjct: 972  GPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPG 1023



 Score =  154 bits (389), Expect = 3e-37
 Identities = 88/185 (47%), Positives = 96/185 (51%), Gaps = 27/185 (14%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERG----- 497
            GPPGP G  G  GS G  GP G+ GQ GEKG PG  GP G  GP+G AG  G RG     
Sbjct: 903  GPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPP 962

Query: 498  -GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL------PGPQGPPGFQGLQ 550
               G +GS GP+G +G  GKPG  G SG+ GPPGP G  GL      PG  G PG  GL 
Sbjct: 963  GMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLP 1022

Query: 551  GTVGEPGVPGPRG------LPGLPGVPGMPGPKGP---------PGPPGPSGAVVPLALQ 595
            G  G PG  G RG       PG PG PG PGP GP          GP GP+GA  P   +
Sbjct: 1023 GRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSR 1082

Query: 596  NEPTP 600
              P P
Sbjct: 1083 GAPGP 1087



 Score =  152 bits (385), Expect = 8e-37
 Identities = 84/187 (44%), Positives = 91/187 (48%), Gaps = 36/187 (19%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERG--- 497
            L GPPG  GPRG  G QG  G +G  G  G  GE GPPGP G  G  G AG PG  G   
Sbjct: 958  LAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPG 1017

Query: 498  ------------GKGSKGSQGPKGSRGSPGKPGP---------------QGPSGDPGPPG 530
                        GKG +G  G  G+ G+PG PGP                GP+G  G PG
Sbjct: 1018 SDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPG 1077

Query: 531  PPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPK------GPPGPPG 584
            P G  G PGPQGP G +G  G  G  G+ G RG PG PG PG PGP       G PGP G
Sbjct: 1078 PAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAG 1137

Query: 585  PSGAVVP 591
            P G V P
Sbjct: 1138 PRGPVGP 1144



 Score =  152 bits (384), Expect = 1e-36
 Identities = 79/151 (52%), Positives = 86/151 (56%), Gaps = 15/151 (9%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           GPPG  GP G  G  GPPGP    G KGE+G PG PG AG  G  G  GPP      GS 
Sbjct: 837 GPPGVAGPPGGSGPAGPPGPQ---GVKGERGSPGGPGAAGFPGARGLPGPP------GSN 887

Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
           G+ GP G  GSPGK GP GP+G+ G PG PG  G  G  G PG +G  G  G PG PGP 
Sbjct: 888 GNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPL 947

Query: 563 GLP------GLPGVPGMPGPKGPPGPPGPSG 587
           G+       GL G PGMPGP+G PGP G  G
Sbjct: 948 GIAGITGARGLAGPPGMPGPRGSPGPQGVKG 978



 Score =  152 bits (383), Expect = 1e-36
 Identities = 85/187 (45%), Positives = 95/187 (50%), Gaps = 23/187 (12%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           G  G RGP G  G+ G PG  G  G+ G+ G  G PGP GERG  G  G PG +G  G  
Sbjct: 408 GLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKD 467

Query: 503 GSQGPKGS---------RGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553
           GS G  G+         RG+PG  GP GP+G PG  GP G+ G PGP GP G  G  G  
Sbjct: 468 GSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRD 527

Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGP---------PGPPGPSGAVVPLALQNEPTP---- 600
           G PG PG RG+PG PG PG  G  GP         PGPPGPSG      +   P P    
Sbjct: 528 GVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGND 587

Query: 601 -APEDNG 606
            AP  NG
Sbjct: 588 GAPGKNG 594



 Score =  151 bits (381), Expect = 2e-36
 Identities = 82/161 (50%), Positives = 92/161 (57%), Gaps = 21/161 (13%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERG------PIGPAGP 492
           +G PGPRG RG+ G  G PG  G  G+ G  GEPG    PG AGERG      P GP G 
Sbjct: 440 KGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGI 499

Query: 493 PGERGGKGSKGSQGPKGSRGSPGKPG----PQGPS--GDPGPPGPPGKEGLPGPQGPPGF 546
           PGE+G  G +G+ GP G RG+ G+PG    P GP   G PG PG PG +G PGP G    
Sbjct: 500 PGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGS--- 556

Query: 547 QGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
              QG  G PG PGP G  G PGV G PGPKG  G PG +G
Sbjct: 557 ---QGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNG 594



 Score =  151 bits (381), Expect = 2e-36
 Identities = 81/172 (47%), Positives = 88/172 (51%), Gaps = 27/172 (15%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGN---------KGQKGEKGEPGPPGPAGERGPIGPAGPP 493
            G PGP GP G  G  GPPGP GN          G KG+ G+PG  G  G +GP G  GP 
Sbjct: 888  GNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPL 947

Query: 494  GERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553
            G  G  G++G  GP G  G  G PGPQG  G+ G PG  G  G  GP GP G  GL GT 
Sbjct: 948  GIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTA 1007

Query: 554  GEP---GVPGPRGLP---------------GLPGVPGMPGPKGPPGPPGPSG 587
            GEP   G PG  GLP               G PG PG PG  GPPGP GP+G
Sbjct: 1008 GEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAG 1059



 Score =  150 bits (380), Expect = 3e-36
 Identities = 87/209 (41%), Positives = 99/209 (47%), Gaps = 54/209 (25%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG------------PPGPAGERGPIGPA 490
           G PG  GP+GD G+ G PG  G+ G  GE+G PG            PPGP G +G  GP 
Sbjct: 654 GKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPP 713

Query: 491 GPPG------------ERGGKGSKGSQGPKGSRGSPG------KPGPQGPSGDPGPPGP- 531
           GPPG            ERGG GS G +G KG  G PG      K GP+GP+G  GPPGP 
Sbjct: 714 GPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPA 773

Query: 532 -----------------------PGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLP 568
                                  PG+ G  GP GP GF G  G  GEPG  G RG PG  
Sbjct: 774 GQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEK 833

Query: 569 GVPGMPGPKGPPGPPGPSGAVVPLALQNE 597
           G  G PG  GPPG  GP+G   P  ++ E
Sbjct: 834 GEGGPPGVAGPPGGSGPAGPPGPQGVKGE 862



 Score =  149 bits (376), Expect = 9e-36
 Identities = 86/183 (46%), Positives = 99/183 (54%), Gaps = 16/183 (8%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG---------PIGPAG 491
           L GPPG +GP G  G  G  G  G  G+ GEKGE G PG  GE G         P+GP G
Sbjct: 244 LPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRG 303

Query: 492 PPGERGGKG---SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG 548
            PGERG  G   + G++G  G+RGS G+PGP GP G  G PG PG +G  GP G PG  G
Sbjct: 304 APGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNG 363

Query: 549 LQGTVGEPGV---PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDN 605
             G  GEPG     G +G PG PG+ G PG KG  GP G  GA   +  +  P PA   N
Sbjct: 364 APGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGA-N 422

Query: 606 GCP 608
           G P
Sbjct: 423 GAP 425



 Score =  149 bits (376), Expect = 9e-36
 Identities = 78/168 (46%), Positives = 86/168 (51%), Gaps = 6/168 (3%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           GP GPRG  G+RG  G PG  G +G  G +G  G PGP G  G  G  G PG +G  G  
Sbjct: 297 GPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPA 356

Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLP------GPQGPPGFQGLQGTVGEP 556
           GS G  G+ G  G+PGPQG +G  GPPGPPG  G P      GP G PG  GL G  G P
Sbjct: 357 GSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPP 416

Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPED 604
           G  G  G PGL G  G PG  G  G PGP G      +   P    ED
Sbjct: 417 GPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGED 464



 Score =  146 bits (368), Expect = 8e-35
 Identities = 85/207 (41%), Positives = 96/207 (46%), Gaps = 26/207 (12%)

Query: 428 DSKHGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI 487
           D K G  +       GP GP GP G  G+ G PG  G+ G +G  GEPG  GP+G  GP 
Sbjct: 159 DVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPP 218

Query: 488 GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQ 547
           G  GP G  G  G  G  G  G RG PG PG +GP+G PG PG  G  G  G  G  G  
Sbjct: 219 GAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGET 278

Query: 548 GLQGTVGEPGVP---------GPRGLPGLPGVPGMP---------------GPKGPPGPP 583
           G  G  GE G+P         GPRG PG  G PG+P               G  GPPGPP
Sbjct: 279 GAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPP 338

Query: 584 GPSGAVVPLALQNEPTPA--PEDNGCP 608
           G +G       + E  PA  P  NG P
Sbjct: 339 GTAGFPGSPGAKGEVGPAGSPGSNGAP 365



 Score =  142 bits (358), Expect = 1e-33
 Identities = 74/164 (45%), Positives = 83/164 (50%), Gaps = 6/164 (3%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           GP GP GP G  G  GP G  G  G+ G  GE G PGP G +GP G  G PG +G +G  
Sbjct: 210 GPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFD 269

Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV---- 558
           G  G KG  G+PG  G  G  G+ G PGP G  G PG +G PG  G  G  G  G     
Sbjct: 270 GRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSD 329

Query: 559 --PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP 600
             PGP G PG  G PG PG KG  GP G  G+      + EP P
Sbjct: 330 GQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGP 373



 Score =  141 bits (356), Expect = 2e-33
 Identities = 78/180 (43%), Positives = 89/180 (49%), Gaps = 21/180 (11%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           GPPG  G  G  G++G  GP G+ G  G  G+ G PGP G  G  GP GPPG  G  G K
Sbjct: 336 GPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGK 395

Query: 503 GSQGPKGSRGSPG------KPGPQGPSGDPG------PPGPPGKEGLPGPQGP------- 543
           G  GP G  G+PG       PGP G +G PG       PG  G +G PGP+G        
Sbjct: 396 GEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIP 455

Query: 544 --PGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601
             PG +G  G  G PG PG  GLPG  G  G PG +GP GP G  G   P   +  P PA
Sbjct: 456 GVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPA 515



 Score =  141 bits (355), Expect = 2e-33
 Identities = 76/172 (44%), Positives = 90/172 (52%), Gaps = 21/172 (12%)

Query: 435 IKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG 494
           I  F  ++G  G  G  G++G  G PG  G  G  GE G PGP GP   RG  G  G PG
Sbjct: 256 IPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGP---RGAPGERGRPG 312

Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDP---------GPPGPPGKEGLPGPQGPPG 545
             G  G++G+ G +GS G PG PGP G +G P         GP G PG  G PG +G PG
Sbjct: 313 LPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPG 372

Query: 546 FQGLQGTVGEPGVPGPRGLP---------GLPGVPGMPGPKGPPGPPGPSGA 588
            QG  G  G PG PG  G P         G+PG PG+ G +GPPGP G +GA
Sbjct: 373 PQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGA 424



 Score =  140 bits (352), Expect = 6e-33
 Identities = 85/218 (38%), Positives = 97/218 (44%), Gaps = 57/218 (26%)

Query: 444 PPGPRGPRGDRGSQGPPGPTGNK------GQKGEKGEPGPP------------------- 478
           PP  +GP+G +G  GPPG  G        GQ G  G PGPP                   
Sbjct: 98  PPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDS 157

Query: 479 ----------GPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGP 528
                     G AG  GP GP GPPG  G  G  GS G  G +G PG+PG  GPSG PGP
Sbjct: 158 YDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGP 217

Query: 529 P---GPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGV--------------- 570
           P   GP G  G  G  G PG  G +G  G PG+ GP G+PG PG+               
Sbjct: 218 PGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGE 277

Query: 571 PGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
            G PG KG  G PG +GA  P+     P  AP + G P
Sbjct: 278 TGAPGLKGENGLPGENGAPGPMG----PRGAPGERGRP 311



 Score =  139 bits (351), Expect = 7e-33
 Identities = 78/165 (47%), Positives = 86/165 (52%), Gaps = 18/165 (10%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGP------TGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG 494
           L G  G RG  G RGS G PGP       G  G  G KGE GP G  G  G  G  G PG
Sbjct: 313 LPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPG 372

Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVG 554
            +G  G++G  GP G  GSPG  G  GP+G PG PG  G  G PGP G  G  GL+G  G
Sbjct: 373 PQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAG 432

Query: 555 EP------GVPGPRGLPGLPGVPGMPGPK------GPPGPPGPSG 587
           EP      G PGPRG  G  G+PG+PG K      G PG PG +G
Sbjct: 433 EPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANG 477



 Score =  128 bits (322), Expect = 2e-29
 Identities = 76/198 (38%), Positives = 81/198 (40%), Gaps = 53/198 (26%)

Query: 443 GPPGPRGPRGDRG------SQ--------------------------------------- 457
           GPPG  G  GD G      S                                        
Sbjct: 112 GPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAG 171

Query: 458 --------GPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKG 509
                   GPPGP G  G  G  G PG  GP GE G  GP+GPPG  G  G  G  G  G
Sbjct: 172 YPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDG 231

Query: 510 SRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPG 569
             G PG+PG +G  G PG  GP G  G PG +G  GF G  G  GE G PG +G  GLPG
Sbjct: 232 ESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPG 291

Query: 570 VPGMPGPKGPPGPPGPSG 587
             G PGP GP G PG  G
Sbjct: 292 ENGAPGPMGPRGAPGERG 309



 Score =  111 bits (277), Expect = 3e-24
 Identities = 72/184 (39%), Positives = 78/184 (42%), Gaps = 47/184 (25%)

Query: 445 PGPRGPRGD------RGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498
           P P  P G+      +    P  P   +G +G KG+PGPPG  G  G  G  G PG    
Sbjct: 75  PNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPG---- 130

Query: 499 KGSKGSQGPKG--------------------------SRGSPGKPGPQGPSGDPGPPGP- 531
             S GS GP G                            G  G PGP GP G PGPPG  
Sbjct: 131 --SPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTS 188

Query: 532 --PGKEGLPGPQGPPGFQGLQGTVGEPGVP------GPRGLPGLPGVPGMPGPKGPPGPP 583
             PG  G PG QGPPG  G  G  G PG P      GP G  G  G PG PG +G PGPP
Sbjct: 189 GHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPP 248

Query: 584 GPSG 587
           G  G
Sbjct: 249 GIKG 252



 Score =  108 bits (269), Expect = 2e-23
 Identities = 53/114 (46%), Positives = 64/114 (56%), Gaps = 24/114 (21%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPG---------------PAGERGP 486
            +G PGP+GPRGD+G  G  G  G KG +G  G PG PG               PAG RGP
Sbjct: 1082 RGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGP 1141

Query: 487  IGPAGPPGERGGKGS---------KGSQGPKGSRGSPGKPGPQGPSGDPGPPGP 531
            +GP+GPPG+ G  G          +G++G +GS GSPG PG  GP G PG PGP
Sbjct: 1142 VGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGP 1195



 Score =  103 bits (256), Expect = 8e-22
 Identities = 63/171 (36%), Positives = 66/171 (38%), Gaps = 37/171 (21%)

Query: 475 PGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGK 534
           P P  P GE   + P  P         +G QGPKG  G PG PG  G  G PG PG PG 
Sbjct: 75  PNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGS 134

Query: 535 -----------------------------------EGLPGPQGPPGFQGLQGTVGEPGVP 559
                                               G PGP GPPG  G  GT G PG P
Sbjct: 135 PGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSP 194

Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP--TPAPEDNGCP 608
           G  G  G PG PG  GP GPPGPPG  G   P     E      P + G P
Sbjct: 195 GSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLP 245


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  169 bits (428), Expect = 9e-42
 Identities = 86/179 (48%), Positives = 100/179 (55%), Gaps = 24/179 (13%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTG---------------------NKGQKGEKGEPGPPGPA 481
            GPPG +GP GD G +G PGP G                     +KG+ G+ G+PGPPGP+
Sbjct: 1303 GPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPS 1362

Query: 482  GERGPIGPAG---PPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLP 538
            GE GP GP G   PPG  G +G +G +G KG  G+ G PG  GP G  GP G PG EGL 
Sbjct: 1363 GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR 1422

Query: 539  GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNE 597
            G  GP G QGL G  G+ G PGP G PGLPG+ G PG KG  G PG  G + P   Q E
Sbjct: 1423 GIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE 1481



 Score =  166 bits (421), Expect = 6e-41
 Identities = 91/203 (44%), Positives = 101/203 (49%), Gaps = 45/203 (22%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP---------- 492
            GP G RGP G RGS+G  GPTG  G KG  G  GPPGP GERGP GP GP          
Sbjct: 889  GPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPP 948

Query: 493  --------PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD---------PGPPGPPGKE 535
                    PG  G +G  G QG  G  G  G  GPQGP+G+         PGPPGPPG++
Sbjct: 949  GPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQ 1008

Query: 536  GLPGPQG---------PPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGP- 585
            GLPG  G         P G  G  G  G  G PG RGLPG  G PG+ G +GP GPPGP 
Sbjct: 1009 GLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV 1068

Query: 586  --------SGAVVPLALQNEPTP 600
                    +G   P+ L   P P
Sbjct: 1069 GSPGERGSAGTAGPIGLPGRPGP 1091



 Score =  164 bits (414), Expect = 4e-40
 Identities = 85/177 (48%), Positives = 101/177 (57%), Gaps = 11/177 (6%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE---PGPPGPAGERGPIGPAGPPGERGGK 499
            G PGP G  G++G  G PG  G  G++G KG    PG PG  GE+G  G AG PG RG +
Sbjct: 835  GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 894

Query: 500  GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV- 558
            G  G +G +G+RG  GKPGP+G SG  GPPGPPG+ G  GPQGP GF G +G  G PG  
Sbjct: 895  GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 954

Query: 559  -----PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP--APEDNGCP 608
                 PG RG  G  G  G PGP G  GP GP+G   P+  +  P P   P + G P
Sbjct: 955  GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLP 1011



 Score =  163 bits (412), Expect = 6e-40
 Identities = 92/183 (50%), Positives = 97/183 (53%), Gaps = 33/183 (18%)

Query: 442  QGPPGPRGPRGDRGS---------------QGPPGPTGNKGQKGEKGEPGP------PGP 480
            QGPPGP G  G+RGS               QGPPGP G KG  GEKG  GP       GP
Sbjct: 1062 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1121

Query: 481  AGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP 540
             G  GP GPAG PGE G KG  G  G KGS+G  G+ GP GP G  GP G PG  G  G 
Sbjct: 1122 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGE 1181

Query: 541  QGPPGFQGL------QGTVGEPGVPGPRGLPGLPGVPGMP------GPKGPPGPPGPSGA 588
             GP G QG+      +G  G PG PGP GL GLPG PG        GP GPPGPPGP G 
Sbjct: 1182 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGP 1241

Query: 589  VVP 591
              P
Sbjct: 1242 QGP 1244



 Score =  162 bits (410), Expect = 1e-39
 Identities = 84/164 (51%), Positives = 94/164 (57%), Gaps = 12/164 (7%)

Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGP 492
           + F  L G PG +G RG+RG QGPPGP G+ G +GE GE GP   PG AG RG +GP G 
Sbjct: 612 RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGT 671

Query: 493 PGE---------RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGP 543
           PG           G  G KG+ GP+G  G PG+ G  GP G PGP GP G  G  GPQG 
Sbjct: 672 PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 731

Query: 544 PGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           PG  GL G  G PG PG  G  G  G  G PGP+GP G PGP G
Sbjct: 732 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRG 775



 Score =  162 bits (410), Expect = 1e-39
 Identities = 90/197 (45%), Positives = 100/197 (50%), Gaps = 36/197 (18%)

Query: 443  GPPGPRGPRGDRGSQGPPGP---------TGNKGQKGEKGEPGPP------GPAGERGPI 487
            GPPGPRGP+G  G+ GP GP          G KG+ GE G PGPP      GP GERG  
Sbjct: 1234 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1293

Query: 488  GPAGPPGER---GGKGSKGSQGPKGS---------RGSPGKPGP---------QGPSGDP 526
            G AGPPG     G KG  G  GPKG+          G PG+PGP         +G  GDP
Sbjct: 1294 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDP 1353

Query: 527  GPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPS 586
            G PGPPG  G  GP GPPG +G  G  G  G  G +G  G  G  G PG  GP GP GP+
Sbjct: 1354 GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPA 1413

Query: 587  GAVVPLALQNEPTPAPE 603
            G   P  L+  P P  E
Sbjct: 1414 GKPGPEGLRGIPGPVGE 1430



 Score =  160 bits (406), Expect = 3e-39
 Identities = 86/173 (49%), Positives = 95/173 (54%), Gaps = 11/173 (6%)

Query: 443  GPPGPRG---PRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---PAGPPGER 496
            GPPG  G   P+G+RG +G  GP G  G  G KG PG  GP G  GP+G     GPPGE 
Sbjct: 1276 GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEP 1335

Query: 497  GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
            G  G  G  G KG  G PG+PGP GPSG+ GPPGPPGK G PG  G  G QG +G  GE 
Sbjct: 1336 GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEA 1395

Query: 557  GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609
            G  GP   PG  G  G  GP G PGP G  G   P+  Q  P  A +D   PP
Sbjct: 1396 GAEGP---PGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDG--PP 1443



 Score =  159 bits (403), Expect = 7e-39
 Identities = 82/170 (48%), Positives = 98/170 (57%), Gaps = 7/170 (4%)

Query: 443  GPPGPRG---PRGDRGSQGPPGPTG---NKGQKGEKGEPGPPGPAGERGPIGPAGPPGER 496
            GPPGP G   P G  G +GPPG  G    +G+KG KGE G  GP G+ GP+GP GP G+ 
Sbjct: 1357 GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1416

Query: 497  GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
            G +G +G  GP G +G PG  G  GP G  GPPG PG +G PG +G  G  GL G +G P
Sbjct: 1417 GPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPP 1476

Query: 557  GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP-APEDN 605
            G  G +G  GLPG  G PG KG  G PGP+G + P      P P  P+ N
Sbjct: 1477 GEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN 1526



 Score =  158 bits (400), Expect = 2e-38
 Identities = 85/175 (48%), Positives = 96/175 (54%), Gaps = 18/175 (10%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERG--- 497
           L+GPPGP G  G     GP G  G+ G KGE G+PGP GP G +GP GP G PG+RG   
Sbjct: 539 LRGPPGPMGLTG---RPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPG 595

Query: 498 ---GKGSKGSQGPKGSRGS------PGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG 548
              G+G  G  G KG RG       PG  G +G  G  GPPGPPG +G+ G  G  G +G
Sbjct: 596 ADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRG 655

Query: 549 LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPP---GPSGAVVPLALQNEPTP 600
           L G  G  G+ GPRG PG PG PGM G  GPPGP    GP G   P   Q  P P
Sbjct: 656 LPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 710



 Score =  158 bits (399), Expect = 2e-38
 Identities = 81/158 (51%), Positives = 95/158 (60%), Gaps = 15/158 (9%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG------ERGPIGPAGPPGE 495
           +G PG  G +GDRG  G PG  G+KG +GE+G  GPPGP G      E G IGP G PGE
Sbjct: 600 RGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGE 659

Query: 496 RGGKGSKGSQGPKGSRGSPGK------PGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGL 549
            G +G  G +G  G+ G PG       PGP+G  G  G PGPPG++G PGPQG P   G 
Sbjct: 660 AGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLP---GP 716

Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           QG +G PG  GP+G PGL G+PG  GP G PG  G SG
Sbjct: 717 QGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSG 754



 Score =  157 bits (398), Expect = 3e-38
 Identities = 78/153 (50%), Positives = 89/153 (58%), Gaps = 6/153 (3%)

Query: 441 LQGPPGPRGPRGDR------GSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG 494
           +QGPPGP G  G R      G +G PG  G KG +G  G PG PG  G RG  GP GPPG
Sbjct: 578 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 637

Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVG 554
             G  G +G  G  G RG PG+ GP+G  G  G PG PG+ G+ G  GPPG +G  G  G
Sbjct: 638 PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG 697

Query: 555 EPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           EPG PG +G PG  G+PG  GP GPPG  GP G
Sbjct: 698 EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQG 730



 Score =  156 bits (395), Expect = 6e-38
 Identities = 86/187 (45%), Positives = 96/187 (51%), Gaps = 36/187 (19%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAG------PPG 494
            L GP GP G  G+ G +G  G  G KG KG+KGE GPPGP G +GP+G  G       PG
Sbjct: 1124 LPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPG 1183

Query: 495  ERGGKGSKGSQGPKGSRGSPGKPGP---------------------QGPSGDPGPPGPPG 533
             RG +G  G +G +G+RG PG PGP                      GP G PGP GP G
Sbjct: 1184 PRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQG 1243

Query: 534  KEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPK---------GPPGPPG 584
              G  GPQGPPG  G  G VGE G PG  G PG PG  G+ GPK         GPPG  G
Sbjct: 1244 PNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAG 1303

Query: 585  PSGAVVP 591
            P GA  P
Sbjct: 1304 PPGAKGP 1310



 Score =  154 bits (390), Expect = 2e-37
 Identities = 87/188 (46%), Positives = 95/188 (50%), Gaps = 30/188 (15%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPG---PAGERGPIGPAGPPGERG 497
            L G PG +GP+G  G  G PG  G KG +G  G+PGP G   P G RG  G  GP G+ G
Sbjct: 854  LPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG 913

Query: 498  GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGP---PGPPGKEGLP---------------- 538
             KG+ G  GP G  G  G  GPQGP G PGP   PGPPGK+GLP                
Sbjct: 914  PKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 973

Query: 539  --------GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVV 590
                    GPQGP G  G  G  G PG PGP G  GLPG  G  G KG PGP G SG   
Sbjct: 974  PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDG 1033

Query: 591  PLALQNEP 598
            P  L+  P
Sbjct: 1034 PAGLRGFP 1041



 Score =  154 bits (390), Expect = 2e-37
 Identities = 80/172 (46%), Positives = 90/172 (52%), Gaps = 4/172 (2%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
            +G  G  GP G  G QG PGP G KG+ G+ G  GPPGP G RGP GP G  G +G  GS
Sbjct: 1197 EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGS 1256

Query: 502  KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGP 561
             GS G  G +G PG+ G  GP G+ G  GP G+ G  G  GPPG  G  G  G PG  GP
Sbjct: 1257 VGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGP 1316

Query: 562  RGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP----TPAPEDNGCPP 609
            +G PG  G PG PGP G PGP G  G         +P     P P     PP
Sbjct: 1317 KGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1368



 Score =  153 bits (387), Expect = 5e-37
 Identities = 80/162 (49%), Positives = 87/162 (53%), Gaps = 18/162 (11%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGP------------AGERGPIG 488
            L GPPG +G  GD G  GPPGP G +G +G  G  GP GP             GE G  G
Sbjct: 1214 LPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAG 1273

Query: 489  PAGPPGERGGKGSKGSQGPKGSRGSP---GKPGPQGPSGDPGPPGPPGKEGLPGPQGPPG 545
              GPPGE G  G KG +G KG  G P   G PG +GP GD GP G PG  G PG  GPP 
Sbjct: 1274 NPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP- 1332

Query: 546  FQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
              G  G  G+ GV G +G  G PG PG PGP G  GPPGP G
Sbjct: 1333 --GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPG 1372



 Score =  152 bits (385), Expect = 8e-37
 Identities = 84/173 (48%), Positives = 90/173 (52%), Gaps = 16/173 (9%)

Query: 448 RGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGP 507
           RGP G  G  G PGP G  G  G KGE G PGP G RG  GP GP G+ G +G  G+ G 
Sbjct: 540 RGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGG 599

Query: 508 KGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLP-- 565
           +G  G PG  G +G  G PG PG  G  G  GPQGPPG  G  G  GE G  GPRGLP  
Sbjct: 600 RGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGE 659

Query: 566 ----------GLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
                     G PG PG PG  G  GPPGP G + P   Q EP P P   G P
Sbjct: 660 AGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGP---QGEPGP-PGQQGNP 708



 Score =  152 bits (385), Expect = 8e-37
 Identities = 86/186 (46%), Positives = 96/186 (51%), Gaps = 26/186 (13%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---PAGPPGERGG 498
            +G PGP GP G +G  GPPG  G  G  G  G PGPPGP G +GP G   P GPPG  G 
Sbjct: 1200 RGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGS 1259

Query: 499  KGSKGSQGPKGSRGSPGKPG------PQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552
             G  G +G  G  G+PG PG      P+G  G+ G  GPPG  G PG +GPPG  G +G 
Sbjct: 1260 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1319

Query: 553  ---VGEPGVPGPRGLPGLPGVPGMPGPK------GPPGPPGPSGAVVPLALQNEPTPAPE 603
               VG PG PGP G PG  G  G+ G K      G PGPPGPSG   P        P P 
Sbjct: 1320 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGP--------PGPP 1371

Query: 604  DNGCPP 609
                PP
Sbjct: 1372 GKRGPP 1377



 Score =  150 bits (379), Expect = 4e-36
 Identities = 86/187 (45%), Positives = 97/187 (51%), Gaps = 36/187 (19%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKG------QKGEKGEPGPPGPAGERGPIGPAGPPGE 495
            QGP G  GP G+RG  GPPGP G +G      ++G KG+PGP G +G+ GP G  G PGE
Sbjct: 984  QGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGE 1043

Query: 496  RGG---------KGSKGSQGPKGSRGSPGK------------PGPQGPSGDPGPPGPPGK 534
            RG          KG +G QGP G  GSPG+            PG  GP G PGP G  G 
Sbjct: 1044 RGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGA 1103

Query: 535  EGLPGPQGPPGFQGLQGTVGEPGVPGPRGLP---------GLPGVPGMPGPKGPPGPPGP 585
             G  GPQGP G  G+QG VG PG  GP G P         G PG  G  G KG  GPPGP
Sbjct: 1104 PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGP 1163

Query: 586  SGAVVPL 592
             G   P+
Sbjct: 1164 PGLQGPV 1170



 Score =  149 bits (376), Expect = 9e-36
 Identities = 81/173 (46%), Positives = 93/173 (53%), Gaps = 5/173 (2%)

Query: 439  TILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498
            T  QG  GP GP G  G QGP G TG  G++G  G PGPPG  G  G  G  G  G+ G 
Sbjct: 966  TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 1025

Query: 499  KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT---VGE 555
            +G  G  GP G RG PG+ G  G  G PG  G  G +G PGP G PG +G  GT   +G 
Sbjct: 1026 QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGL 1085

Query: 556  PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA--PEDNG 606
            PG PGP+G PG  G  G PG KGP GP G  G   P+ L     PA  P ++G
Sbjct: 1086 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG 1138



 Score =  145 bits (365), Expect = 2e-34
 Identities = 79/186 (42%), Positives = 98/186 (52%), Gaps = 22/186 (11%)

Query: 443  GPPGPRGP---------------RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI 487
            GPPG RGP               +G+ G++GPPG TG  G +G  G+PGP G  G  GP+
Sbjct: 1369 GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV 1428

Query: 488  GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDP---GPPGPPGKEGLPGPQGPP 544
            G  G PG  G  G  G  GP G  G  G PG +G  G P   G  GPPG++G  G +G P
Sbjct: 1429 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1488

Query: 545  GFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP-TPAPE 603
            G QG  G  G+ G+PGP G  G PG PG+PGP+GP G  G +G   P   + +   P P 
Sbjct: 1489 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTG---PAGQKGDSGLPGPP 1545

Query: 604  DNGCPP 609
             +  PP
Sbjct: 1546 GSPGPP 1551



 Score =  144 bits (364), Expect = 2e-34
 Identities = 84/196 (42%), Positives = 92/196 (46%), Gaps = 51/196 (26%)

Query: 443 GPPGPRGP------RGDRGSQGPPGPTGNKGQKGE------------------------K 472
           GPPGP+GP      RG +G+ G  G  G+KG+KGE                        +
Sbjct: 760 GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 819

Query: 473 GEPGPPGPAGERGPIGPAGPPGERGGKGS---------KGSQGPKGSRGSPGKPGPQ--- 520
           GE GP GP G  GP G  GP G+ G KG           G QGPKGS G PG PG     
Sbjct: 820 GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 879

Query: 521 ---------GPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVP 571
                    GP G  GP GP G  G  GP G PG +G  G  G PG PG RG  G  G  
Sbjct: 880 GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPV 939

Query: 572 GMPGPKGPPGPPGPSG 587
           G PGPKGPPGPPG  G
Sbjct: 940 GFPGPKGPPGPPGKDG 955



 Score =  144 bits (364), Expect = 2e-34
 Identities = 73/145 (50%), Positives = 86/145 (59%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            GP G RG  G+RG  G  G  G KG +G +G PGP G  GERG  G AGP G  G  G +
Sbjct: 1033 GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQ 1092

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
            G  GP G +G+PG+ GPQGP+G  G  GP G  G  GP G PG  G +G +GEPG  G +
Sbjct: 1093 GPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSK 1152

Query: 563  GLPGLPGVPGMPGPKGPPGPPGPSG 587
            G  G  G PG PG +GP G PG +G
Sbjct: 1153 GDKGENGPPGPPGLQGPVGAPGIAG 1177



 Score =  144 bits (363), Expect = 3e-34
 Identities = 79/165 (47%), Positives = 91/165 (55%), Gaps = 15/165 (9%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGPPGERGG 498
           +G PG  G  G  G  GPPGP GN G +GE G PG    PGP G  GP GP GPPGE+G 
Sbjct: 669 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 728

Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDP---GPPGPPGKEGLPGP---QGPPGFQGLQGT 552
           +G  G  G  G+ G PG PG +G SG+    GPPGP G  G PGP   +G  G +GL+G+
Sbjct: 729 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 788

Query: 553 VGE------PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
            GE      PG  G  GL G  G  G  GP+G  GP GP G   P
Sbjct: 789 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP 833



 Score =  144 bits (363), Expect = 3e-34
 Identities = 84/203 (41%), Positives = 98/203 (48%), Gaps = 36/203 (17%)

Query: 443 GPPGPRGPRGDRG------SQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGER 496
           GPPG +GP+G  G      + GPPG  G +GQ GEKG  GPPGP G  G  GP G  G  
Sbjct: 721 GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGAD 780

Query: 497 GGKGSKGSQGPKGSRGSPG---------------------KPGPQGPSGDPGPPGPPG-- 533
           G +G KGS+G KG  G PG                     + GP+GP G  GP G PG  
Sbjct: 781 GVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPS 840

Query: 534 -------KEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPS 586
                  K G+PG  G PG QG +G+ G PG PG  G  G  GV G PGP+G  GP GP 
Sbjct: 841 GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPR 900

Query: 587 GAVVPLALQNEPTPAPEDNGCPP 609
           G+        +P P     G  P
Sbjct: 901 GSRGARGPTGKPGPKGTSGGDGP 923



 Score =  144 bits (362), Expect = 4e-34
 Identities = 84/189 (44%), Positives = 97/189 (51%), Gaps = 32/189 (16%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
            L G  G  G +G  G QGPPGP G+ G++G  G  GP G  G  GP GP GP GE+G  G
Sbjct: 1046 LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1105

Query: 501  SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP---PGKEGLPGPQGPPGFQGLQGTVGEPG 557
             KG QGP G      + G QGP G PGP GP   PG++G  G  G PG +G +G  GE G
Sbjct: 1106 EKGPQGPAG------RDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1159

Query: 558  VPGPRGLPGLPGVPGMPGPKGPPGP------------------PGPSGAVVPLALQNEPT 599
             PGP GL G  G PG+ G  G PGP                  PGP G   P+ LQ  P 
Sbjct: 1160 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG---PIGLQGLPG 1216

Query: 600  PAPE--DNG 606
            P  E  +NG
Sbjct: 1217 PPGEKGENG 1225



 Score =  142 bits (359), Expect = 9e-34
 Identities = 83/193 (43%), Positives = 96/193 (49%), Gaps = 45/193 (23%)

Query: 440 ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP----PGE 495
           +++GPPGP GP G  G  G  GPTG  G  G++G PG PG  G  G  GP G     P  
Sbjct: 451 LVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFR 510

Query: 496 RGGKGSKGS--------------------QGPKGSRGSPGKPGP---------QGPSGDP 526
            GG GSKG                     +GP G  G  G+PGP         +G SGDP
Sbjct: 511 YGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDP 570

Query: 527 GPPGPPGKEGLPGPQGPPGFQGL------QGTVGEPGVPGPRGLPGLPGVP------GMP 574
           GP GP G +G PGP G PG +G       +G  GEPG  G RG  GLPG+P      G  
Sbjct: 571 GPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER 630

Query: 575 GPKGPPGPPGPSG 587
           GP+GPPGPPG  G
Sbjct: 631 GPQGPPGPPGDDG 643



 Score =  142 bits (359), Expect = 9e-34
 Identities = 77/158 (48%), Positives = 88/158 (55%), Gaps = 9/158 (5%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
            +GPPG  GP G +G  G PGP G +G  G  GE G PG AG+ GP GP GPPG  G KG 
Sbjct: 1398 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD 1457

Query: 502  KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGP---PGFQGLQGTVGEPGV 558
             GS+G KG  G  G  GP G  G+ G  G PG +G PG +G    PG  G  G  G PG+
Sbjct: 1458 PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL 1517

Query: 559  PGPRGLPGLPGVPGMPGPK------GPPGPPGPSGAVV 590
            PGP+G  G  G  G  G K      GPPG PGP G V+
Sbjct: 1518 PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVI 1555



 Score =  142 bits (358), Expect = 1e-33
 Identities = 81/172 (47%), Positives = 89/172 (51%), Gaps = 12/172 (6%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
            LQGP G  G  G  G  GP G  G  GQKG++G  G PGP G  G  G  GPPGE+   G
Sbjct: 1166 LQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK---G 1222

Query: 501  SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL---PGPQGPPGFQGLQGTVGEPG 557
              G  GP G  G PG  GPQGP+G  GP GPPG  G     G +G PG  G  G  GE G
Sbjct: 1223 ENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1282

Query: 558  VPGP------RGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPE 603
            V GP      +G  G PG  G PG KGPPG  GP G   P+    +P P  E
Sbjct: 1283 VGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1334



 Score =  141 bits (355), Expect = 2e-33
 Identities = 78/173 (45%), Positives = 93/173 (53%), Gaps = 15/173 (8%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGP---AGPPGERG 497
           + GPPGP+G  G +G  GPPG  GN G +G  G  GP GP GE+GP G    AG PG  G
Sbjct: 683 VDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADG 742

Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGP---------PGFQ- 547
             G  G +G  G +G+ G PGPQGP G PGP G  G +G+ G +G          PGF+ 
Sbjct: 743 PPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKG 802

Query: 548 --GLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598
             GL+G  GE G  GPRG  G  G  G  GP G PGP G +G    L +   P
Sbjct: 803 DMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLP 855



 Score =  136 bits (343), Expect = 6e-32
 Identities = 72/142 (50%), Positives = 83/142 (58%), Gaps = 6/142 (4%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
            + GP G +G  G  G  GPPGP G  G  G KG+PG  G  G  G IG  GPPGE+G KG
Sbjct: 1424 IPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKG 1483

Query: 501  SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPG 560
             +G  G +GS G+ G  G  GP+G  GPPGPP   GLPGPQGP   +G +G+ G  G  G
Sbjct: 1484 DRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP---GLPGPQGP---KGNKGSTGPAGQKG 1537

Query: 561  PRGLPGLPGVPGMPGPKGPPGP 582
              GLPG PG PG PG    P P
Sbjct: 1538 DSGLPGPPGSPGPPGEVIQPLP 1559



 Score = 99.8 bits (247), Expect = 8e-21
 Identities = 76/199 (38%), Positives = 86/199 (43%), Gaps = 46/199 (23%)

Query: 447 PRGPRGDRGSQGPPGPT----------GNKGQKGEKGEP----------GPPGPAGERGP 486
           P  P  +    G P  T          G  G+KG+KGEP          GPPGPAG   P
Sbjct: 405 PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAG---P 461

Query: 487 IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP----PGKEGLPGPQG 542
            G  GPPG +G  G  G  G    RG PG+PG  G  G PGPPG     P + G  G +G
Sbjct: 462 AGIMGPPGLQGPTGPPGDPG---DRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKG 518

Query: 543 PP------GFQGL--QGTVGEPGVPGPRGLPGLPGV---PGMPGPKGPPGPPGPSGAVVP 591
           P         Q +  Q  +   G PGP GL G PG    PG  G KG  G PGP G   P
Sbjct: 519 PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQG---P 575

Query: 592 LALQNEPTPA--PEDNGCP 608
             +Q  P P   P   G P
Sbjct: 576 RGVQGPPGPTGKPGKRGRP 594



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 23/45 (51%), Positives = 29/45 (64%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI 487
            G PGP+GP+G++GS GP G  G+ G  G  G PGPPG   +  PI
Sbjct: 1516 GLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPI 1560


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  169 bits (428), Expect = 9e-42
 Identities = 86/179 (48%), Positives = 100/179 (55%), Gaps = 24/179 (13%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTG---------------------NKGQKGEKGEPGPPGPA 481
            GPPG +GP GD G +G PGP G                     +KG+ G+ G+PGPPGP+
Sbjct: 1252 GPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPS 1311

Query: 482  GERGPIGPAG---PPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLP 538
            GE GP GP G   PPG  G +G +G +G KG  G+ G PG  GP G  GP G PG EGL 
Sbjct: 1312 GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR 1371

Query: 539  GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNE 597
            G  GP G QGL G  G+ G PGP G PGLPG+ G PG KG  G PG  G + P   Q E
Sbjct: 1372 GIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE 1430



 Score =  166 bits (421), Expect = 6e-41
 Identities = 91/203 (44%), Positives = 101/203 (49%), Gaps = 45/203 (22%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP---------- 492
            GP G RGP G RGS+G  GPTG  G KG  G  GPPGP GERGP GP GP          
Sbjct: 838  GPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPP 897

Query: 493  --------PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD---------PGPPGPPGKE 535
                    PG  G +G  G QG  G  G  G  GPQGP+G+         PGPPGPPG++
Sbjct: 898  GPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQ 957

Query: 536  GLPGPQG---------PPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGP- 585
            GLPG  G         P G  G  G  G  G PG RGLPG  G PG+ G +GP GPPGP 
Sbjct: 958  GLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV 1017

Query: 586  --------SGAVVPLALQNEPTP 600
                    +G   P+ L   P P
Sbjct: 1018 GSPGERGSAGTAGPIGLPGRPGP 1040



 Score =  164 bits (414), Expect = 4e-40
 Identities = 85/177 (48%), Positives = 101/177 (57%), Gaps = 11/177 (6%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE---PGPPGPAGERGPIGPAGPPGERGGK 499
           G PGP G  G++G  G PG  G  G++G KG    PG PG  GE+G  G AG PG RG +
Sbjct: 784 GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 843

Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV- 558
           G  G +G +G+RG  GKPGP+G SG  GPPGPPG+ G  GPQGP GF G +G  G PG  
Sbjct: 844 GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 903

Query: 559 -----PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP--APEDNGCP 608
                PG RG  G  G  G PGP G  GP GP+G   P+  +  P P   P + G P
Sbjct: 904 GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLP 960



 Score =  163 bits (412), Expect = 6e-40
 Identities = 92/183 (50%), Positives = 97/183 (53%), Gaps = 33/183 (18%)

Query: 442  QGPPGPRGPRGDRGS---------------QGPPGPTGNKGQKGEKGEPGP------PGP 480
            QGPPGP G  G+RGS               QGPPGP G KG  GEKG  GP       GP
Sbjct: 1011 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1070

Query: 481  AGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP 540
             G  GP GPAG PGE G KG  G  G KGS+G  G+ GP GP G  GP G PG  G  G 
Sbjct: 1071 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGE 1130

Query: 541  QGPPGFQGL------QGTVGEPGVPGPRGLPGLPGVPGMP------GPKGPPGPPGPSGA 588
             GP G QG+      +G  G PG PGP GL GLPG PG        GP GPPGPPGP G 
Sbjct: 1131 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGP 1190

Query: 589  VVP 591
              P
Sbjct: 1191 QGP 1193



 Score =  162 bits (410), Expect = 1e-39
 Identities = 84/164 (51%), Positives = 94/164 (57%), Gaps = 12/164 (7%)

Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGP 492
           + F  L G PG +G RG+RG QGPPGP G+ G +GE GE GP   PG AG RG +GP G 
Sbjct: 561 RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGT 620

Query: 493 PGE---------RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGP 543
           PG           G  G KG+ GP+G  G PG+ G  GP G PGP GP G  G  GPQG 
Sbjct: 621 PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 680

Query: 544 PGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           PG  GL G  G PG PG  G  G  G  G PGP+GP G PGP G
Sbjct: 681 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRG 724



 Score =  162 bits (410), Expect = 1e-39
 Identities = 90/197 (45%), Positives = 100/197 (50%), Gaps = 36/197 (18%)

Query: 443  GPPGPRGPRGDRGSQGPPGP---------TGNKGQKGEKGEPGPP------GPAGERGPI 487
            GPPGPRGP+G  G+ GP GP          G KG+ GE G PGPP      GP GERG  
Sbjct: 1183 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1242

Query: 488  GPAGPPGER---GGKGSKGSQGPKGS---------RGSPGKPGP---------QGPSGDP 526
            G AGPPG     G KG  G  GPKG+          G PG+PGP         +G  GDP
Sbjct: 1243 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDP 1302

Query: 527  GPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPS 586
            G PGPPG  G  GP GPPG +G  G  G  G  G +G  G  G  G PG  GP GP GP+
Sbjct: 1303 GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPA 1362

Query: 587  GAVVPLALQNEPTPAPE 603
            G   P  L+  P P  E
Sbjct: 1363 GKPGPEGLRGIPGPVGE 1379



 Score =  160 bits (406), Expect = 3e-39
 Identities = 86/173 (49%), Positives = 95/173 (54%), Gaps = 11/173 (6%)

Query: 443  GPPGPRG---PRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---PAGPPGER 496
            GPPG  G   P+G+RG +G  GP G  G  G KG PG  GP G  GP+G     GPPGE 
Sbjct: 1225 GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEP 1284

Query: 497  GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
            G  G  G  G KG  G PG+PGP GPSG+ GPPGPPGK G PG  G  G QG +G  GE 
Sbjct: 1285 GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEA 1344

Query: 557  GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609
            G  GP   PG  G  G  GP G PGP G  G   P+  Q  P  A +D   PP
Sbjct: 1345 GAEGP---PGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDG--PP 1392



 Score =  159 bits (403), Expect = 7e-39
 Identities = 82/170 (48%), Positives = 98/170 (57%), Gaps = 7/170 (4%)

Query: 443  GPPGPRG---PRGDRGSQGPPGPTG---NKGQKGEKGEPGPPGPAGERGPIGPAGPPGER 496
            GPPGP G   P G  G +GPPG  G    +G+KG KGE G  GP G+ GP+GP GP G+ 
Sbjct: 1306 GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1365

Query: 497  GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
            G +G +G  GP G +G PG  G  GP G  GPPG PG +G PG +G  G  GL G +G P
Sbjct: 1366 GPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPP 1425

Query: 557  GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP-APEDN 605
            G  G +G  GLPG  G PG KG  G PGP+G + P      P P  P+ N
Sbjct: 1426 GEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN 1475



 Score =  158 bits (400), Expect = 2e-38
 Identities = 85/175 (48%), Positives = 96/175 (54%), Gaps = 18/175 (10%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERG--- 497
           L+GPPGP G  G     GP G  G+ G KGE G+PGP GP G +GP GP G PG+RG   
Sbjct: 488 LRGPPGPMGLTG---RPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPG 544

Query: 498 ---GKGSKGSQGPKGSRGS------PGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG 548
              G+G  G  G KG RG       PG  G +G  G  GPPGPPG +G+ G  G  G +G
Sbjct: 545 ADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRG 604

Query: 549 LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPP---GPSGAVVPLALQNEPTP 600
           L G  G  G+ GPRG PG PG PGM G  GPPGP    GP G   P   Q  P P
Sbjct: 605 LPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 659



 Score =  158 bits (399), Expect = 2e-38
 Identities = 81/158 (51%), Positives = 95/158 (60%), Gaps = 15/158 (9%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG------ERGPIGPAGPPGE 495
           +G PG  G +GDRG  G PG  G+KG +GE+G  GPPGP G      E G IGP G PGE
Sbjct: 549 RGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGE 608

Query: 496 RGGKGSKGSQGPKGSRGSPGK------PGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGL 549
            G +G  G +G  G+ G PG       PGP+G  G  G PGPPG++G PGPQG P   G 
Sbjct: 609 AGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLP---GP 665

Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           QG +G PG  GP+G PGL G+PG  GP G PG  G SG
Sbjct: 666 QGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSG 703



 Score =  157 bits (398), Expect = 3e-38
 Identities = 78/153 (50%), Positives = 89/153 (58%), Gaps = 6/153 (3%)

Query: 441 LQGPPGPRGPRGDR------GSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG 494
           +QGPPGP G  G R      G +G PG  G KG +G  G PG PG  G RG  GP GPPG
Sbjct: 527 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 586

Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVG 554
             G  G +G  G  G RG PG+ GP+G  G  G PG PG+ G+ G  GPPG +G  G  G
Sbjct: 587 PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG 646

Query: 555 EPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           EPG PG +G PG  G+PG  GP GPPG  GP G
Sbjct: 647 EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQG 679



 Score =  156 bits (395), Expect = 6e-38
 Identities = 86/187 (45%), Positives = 96/187 (51%), Gaps = 36/187 (19%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAG------PPG 494
            L GP GP G  G+ G +G  G  G KG KG+KGE GPPGP G +GP+G  G       PG
Sbjct: 1073 LPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPG 1132

Query: 495  ERGGKGSKGSQGPKGSRGSPGKPGP---------------------QGPSGDPGPPGPPG 533
             RG +G  G +G +G+RG PG PGP                      GP G PGP GP G
Sbjct: 1133 PRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQG 1192

Query: 534  KEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPK---------GPPGPPG 584
              G  GPQGPPG  G  G VGE G PG  G PG PG  G+ GPK         GPPG  G
Sbjct: 1193 PNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAG 1252

Query: 585  PSGAVVP 591
            P GA  P
Sbjct: 1253 PPGAKGP 1259



 Score =  154 bits (390), Expect = 2e-37
 Identities = 87/188 (46%), Positives = 95/188 (50%), Gaps = 30/188 (15%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPG---PAGERGPIGPAGPPGERG 497
           L G PG +GP+G  G  G PG  G KG +G  G+PGP G   P G RG  G  GP G+ G
Sbjct: 803 LPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG 862

Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGP---PGPPGKEGLP---------------- 538
            KG+ G  GP G  G  G  GPQGP G PGP   PGPPGK+GLP                
Sbjct: 863 PKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 922

Query: 539 --------GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVV 590
                   GPQGP G  G  G  G PG PGP G  GLPG  G  G KG PGP G SG   
Sbjct: 923 PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDG 982

Query: 591 PLALQNEP 598
           P  L+  P
Sbjct: 983 PAGLRGFP 990



 Score =  154 bits (390), Expect = 2e-37
 Identities = 80/172 (46%), Positives = 90/172 (52%), Gaps = 4/172 (2%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
            +G  G  GP G  G QG PGP G KG+ G+ G  GPPGP G RGP GP G  G +G  GS
Sbjct: 1146 EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGS 1205

Query: 502  KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGP 561
             GS G  G +G PG+ G  GP G+ G  GP G+ G  G  GPPG  G  G  G PG  GP
Sbjct: 1206 VGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGP 1265

Query: 562  RGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP----TPAPEDNGCPP 609
            +G PG  G PG PGP G PGP G  G         +P     P P     PP
Sbjct: 1266 KGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1317



 Score =  153 bits (387), Expect = 5e-37
 Identities = 80/162 (49%), Positives = 87/162 (53%), Gaps = 18/162 (11%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGP------------AGERGPIG 488
            L GPPG +G  GD G  GPPGP G +G +G  G  GP GP             GE G  G
Sbjct: 1163 LPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAG 1222

Query: 489  PAGPPGERGGKGSKGSQGPKGSRGSP---GKPGPQGPSGDPGPPGPPGKEGLPGPQGPPG 545
              GPPGE G  G KG +G KG  G P   G PG +GP GD GP G PG  G PG  GPP 
Sbjct: 1223 NPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP- 1281

Query: 546  FQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
              G  G  G+ GV G +G  G PG PG PGP G  GPPGP G
Sbjct: 1282 --GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPG 1321



 Score =  152 bits (385), Expect = 8e-37
 Identities = 84/173 (48%), Positives = 90/173 (52%), Gaps = 16/173 (9%)

Query: 448 RGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGP 507
           RGP G  G  G PGP G  G  G KGE G PGP G RG  GP GP G+ G +G  G+ G 
Sbjct: 489 RGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGG 548

Query: 508 KGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLP-- 565
           +G  G PG  G +G  G PG PG  G  G  GPQGPPG  G  G  GE G  GPRGLP  
Sbjct: 549 RGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGE 608

Query: 566 ----------GLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
                     G PG PG PG  G  GPPGP G + P   Q EP P P   G P
Sbjct: 609 AGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGP---QGEPGP-PGQQGNP 657



 Score =  152 bits (385), Expect = 8e-37
 Identities = 86/186 (46%), Positives = 96/186 (51%), Gaps = 26/186 (13%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---PAGPPGERGG 498
            +G PGP GP G +G  GPPG  G  G  G  G PGPPGP G +GP G   P GPPG  G 
Sbjct: 1149 RGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGS 1208

Query: 499  KGSKGSQGPKGSRGSPGKPG------PQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552
             G  G +G  G  G+PG PG      P+G  G+ G  GPPG  G PG +GPPG  G +G 
Sbjct: 1209 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1268

Query: 553  ---VGEPGVPGPRGLPGLPGVPGMPGPK------GPPGPPGPSGAVVPLALQNEPTPAPE 603
               VG PG PGP G PG  G  G+ G K      G PGPPGPSG   P        P P 
Sbjct: 1269 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGP--------PGPP 1320

Query: 604  DNGCPP 609
                PP
Sbjct: 1321 GKRGPP 1326



 Score =  150 bits (379), Expect = 4e-36
 Identities = 86/187 (45%), Positives = 97/187 (51%), Gaps = 36/187 (19%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKG------QKGEKGEPGPPGPAGERGPIGPAGPPGE 495
            QGP G  GP G+RG  GPPGP G +G      ++G KG+PGP G +G+ GP G  G PGE
Sbjct: 933  QGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGE 992

Query: 496  RGG---------KGSKGSQGPKGSRGSPGK------------PGPQGPSGDPGPPGPPGK 534
            RG          KG +G QGP G  GSPG+            PG  GP G PGP G  G 
Sbjct: 993  RGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGA 1052

Query: 535  EGLPGPQGPPGFQGLQGTVGEPGVPGPRGLP---------GLPGVPGMPGPKGPPGPPGP 585
             G  GPQGP G  G+QG VG PG  GP G P         G PG  G  G KG  GPPGP
Sbjct: 1053 PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGP 1112

Query: 586  SGAVVPL 592
             G   P+
Sbjct: 1113 PGLQGPV 1119



 Score =  149 bits (376), Expect = 9e-36
 Identities = 81/173 (46%), Positives = 93/173 (53%), Gaps = 5/173 (2%)

Query: 439  TILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498
            T  QG  GP GP G  G QGP G TG  G++G  G PGPPG  G  G  G  G  G+ G 
Sbjct: 915  TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 974

Query: 499  KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT---VGE 555
            +G  G  GP G RG PG+ G  G  G PG  G  G +G PGP G PG +G  GT   +G 
Sbjct: 975  QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGL 1034

Query: 556  PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA--PEDNG 606
            PG PGP+G PG  G  G PG KGP GP G  G   P+ L     PA  P ++G
Sbjct: 1035 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG 1087



 Score =  145 bits (365), Expect = 2e-34
 Identities = 79/186 (42%), Positives = 98/186 (52%), Gaps = 22/186 (11%)

Query: 443  GPPGPRGP---------------RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI 487
            GPPG RGP               +G+ G++GPPG TG  G +G  G+PGP G  G  GP+
Sbjct: 1318 GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV 1377

Query: 488  GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDP---GPPGPPGKEGLPGPQGPP 544
            G  G PG  G  G  G  GP G  G  G PG +G  G P   G  GPPG++G  G +G P
Sbjct: 1378 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1437

Query: 545  GFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP-TPAPE 603
            G QG  G  G+ G+PGP G  G PG PG+PGP+GP G  G +G   P   + +   P P 
Sbjct: 1438 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTG---PAGQKGDSGLPGPP 1494

Query: 604  DNGCPP 609
             +  PP
Sbjct: 1495 GSPGPP 1500



 Score =  144 bits (364), Expect = 2e-34
 Identities = 84/196 (42%), Positives = 92/196 (46%), Gaps = 51/196 (26%)

Query: 443 GPPGPRGP------RGDRGSQGPPGPTGNKGQKGE------------------------K 472
           GPPGP+GP      RG +G+ G  G  G+KG+KGE                        +
Sbjct: 709 GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 768

Query: 473 GEPGPPGPAGERGPIGPAGPPGERGGKGS---------KGSQGPKGSRGSPGKPGPQ--- 520
           GE GP GP G  GP G  GP G+ G KG           G QGPKGS G PG PG     
Sbjct: 769 GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 828

Query: 521 ---------GPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVP 571
                    GP G  GP GP G  G  GP G PG +G  G  G PG PG RG  G  G  
Sbjct: 829 GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPV 888

Query: 572 GMPGPKGPPGPPGPSG 587
           G PGPKGPPGPPG  G
Sbjct: 889 GFPGPKGPPGPPGKDG 904



 Score =  144 bits (364), Expect = 2e-34
 Identities = 73/145 (50%), Positives = 86/145 (59%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            GP G RG  G+RG  G  G  G KG +G +G PGP G  GERG  G AGP G  G  G +
Sbjct: 982  GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQ 1041

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
            G  GP G +G+PG+ GPQGP+G  G  GP G  G  GP G PG  G +G +GEPG  G +
Sbjct: 1042 GPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSK 1101

Query: 563  GLPGLPGVPGMPGPKGPPGPPGPSG 587
            G  G  G PG PG +GP G PG +G
Sbjct: 1102 GDKGENGPPGPPGLQGPVGAPGIAG 1126



 Score =  144 bits (363), Expect = 3e-34
 Identities = 79/165 (47%), Positives = 91/165 (55%), Gaps = 15/165 (9%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGPPGERGG 498
           +G PG  G  G  G  GPPGP GN G +GE G PG    PGP G  GP GP GPPGE+G 
Sbjct: 618 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 677

Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDP---GPPGPPGKEGLPGP---QGPPGFQGLQGT 552
           +G  G  G  G+ G PG PG +G SG+    GPPGP G  G PGP   +G  G +GL+G+
Sbjct: 678 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 737

Query: 553 VGE------PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
            GE      PG  G  GL G  G  G  GP+G  GP GP G   P
Sbjct: 738 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP 782



 Score =  144 bits (363), Expect = 3e-34
 Identities = 84/203 (41%), Positives = 98/203 (48%), Gaps = 36/203 (17%)

Query: 443 GPPGPRGPRGDRG------SQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGER 496
           GPPG +GP+G  G      + GPPG  G +GQ GEKG  GPPGP G  G  GP G  G  
Sbjct: 670 GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGAD 729

Query: 497 GGKGSKGSQGPKGSRGSPG---------------------KPGPQGPSGDPGPPGPPG-- 533
           G +G KGS+G KG  G PG                     + GP+GP G  GP G PG  
Sbjct: 730 GVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPS 789

Query: 534 -------KEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPS 586
                  K G+PG  G PG QG +G+ G PG PG  G  G  GV G PGP+G  GP GP 
Sbjct: 790 GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPR 849

Query: 587 GAVVPLALQNEPTPAPEDNGCPP 609
           G+        +P P     G  P
Sbjct: 850 GSRGARGPTGKPGPKGTSGGDGP 872



 Score =  144 bits (362), Expect = 4e-34
 Identities = 84/189 (44%), Positives = 97/189 (51%), Gaps = 32/189 (16%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
            L G  G  G +G  G QGPPGP G+ G++G  G  GP G  G  GP GP GP GE+G  G
Sbjct: 995  LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1054

Query: 501  SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP---PGKEGLPGPQGPPGFQGLQGTVGEPG 557
             KG QGP G      + G QGP G PGP GP   PG++G  G  G PG +G +G  GE G
Sbjct: 1055 EKGPQGPAG------RDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1108

Query: 558  VPGPRGLPGLPGVPGMPGPKGPPGP------------------PGPSGAVVPLALQNEPT 599
             PGP GL G  G PG+ G  G PGP                  PGP G   P+ LQ  P 
Sbjct: 1109 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG---PIGLQGLPG 1165

Query: 600  PAPE--DNG 606
            P  E  +NG
Sbjct: 1166 PPGEKGENG 1174



 Score =  142 bits (359), Expect = 9e-34
 Identities = 83/193 (43%), Positives = 96/193 (49%), Gaps = 45/193 (23%)

Query: 440 ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP----PGE 495
           +++GPPGP GP G  G  G  GPTG  G  G++G PG PG  G  G  GP G     P  
Sbjct: 400 LVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFR 459

Query: 496 RGGKGSKGS--------------------QGPKGSRGSPGKPGP---------QGPSGDP 526
            GG GSKG                     +GP G  G  G+PGP         +G SGDP
Sbjct: 460 YGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDP 519

Query: 527 GPPGPPGKEGLPGPQGPPGFQGL------QGTVGEPGVPGPRGLPGLPGVP------GMP 574
           GP GP G +G PGP G PG +G       +G  GEPG  G RG  GLPG+P      G  
Sbjct: 520 GPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER 579

Query: 575 GPKGPPGPPGPSG 587
           GP+GPPGPPG  G
Sbjct: 580 GPQGPPGPPGDDG 592



 Score =  142 bits (359), Expect = 9e-34
 Identities = 77/158 (48%), Positives = 88/158 (55%), Gaps = 9/158 (5%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
            +GPPG  GP G +G  G PGP G +G  G  GE G PG AG+ GP GP GPPG  G KG 
Sbjct: 1347 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD 1406

Query: 502  KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGP---PGFQGLQGTVGEPGV 558
             GS+G KG  G  G  GP G  G+ G  G PG +G PG +G    PG  G  G  G PG+
Sbjct: 1407 PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL 1466

Query: 559  PGPRGLPGLPGVPGMPGPK------GPPGPPGPSGAVV 590
            PGP+G  G  G  G  G K      GPPG PGP G V+
Sbjct: 1467 PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVI 1504



 Score =  142 bits (358), Expect = 1e-33
 Identities = 81/172 (47%), Positives = 89/172 (51%), Gaps = 12/172 (6%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
            LQGP G  G  G  G  GP G  G  GQKG++G  G PGP G  G  G  GPPGE+   G
Sbjct: 1115 LQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK---G 1171

Query: 501  SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL---PGPQGPPGFQGLQGTVGEPG 557
              G  GP G  G PG  GPQGP+G  GP GPPG  G     G +G PG  G  G  GE G
Sbjct: 1172 ENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1231

Query: 558  VPGP------RGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPE 603
            V GP      +G  G PG  G PG KGPPG  GP G   P+    +P P  E
Sbjct: 1232 VGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1283



 Score =  141 bits (355), Expect = 2e-33
 Identities = 78/173 (45%), Positives = 93/173 (53%), Gaps = 15/173 (8%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGP---AGPPGERG 497
           + GPPGP+G  G +G  GPPG  GN G +G  G  GP GP GE+GP G    AG PG  G
Sbjct: 632 VDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADG 691

Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGP---------PGFQ- 547
             G  G +G  G +G+ G PGPQGP G PGP G  G +G+ G +G          PGF+ 
Sbjct: 692 PPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKG 751

Query: 548 --GLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598
             GL+G  GE G  GPRG  G  G  G  GP G PGP G +G    L +   P
Sbjct: 752 DMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLP 804



 Score =  136 bits (343), Expect = 6e-32
 Identities = 72/142 (50%), Positives = 83/142 (58%), Gaps = 6/142 (4%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
            + GP G +G  G  G  GPPGP G  G  G KG+PG  G  G  G IG  GPPGE+G KG
Sbjct: 1373 IPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKG 1432

Query: 501  SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPG 560
             +G  G +GS G+ G  G  GP+G  GPPGPP   GLPGPQGP   +G +G+ G  G  G
Sbjct: 1433 DRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP---GLPGPQGP---KGNKGSTGPAGQKG 1486

Query: 561  PRGLPGLPGVPGMPGPKGPPGP 582
              GLPG PG PG PG    P P
Sbjct: 1487 DSGLPGPPGSPGPPGEVIQPLP 1508



 Score = 99.8 bits (247), Expect = 8e-21
 Identities = 76/199 (38%), Positives = 86/199 (43%), Gaps = 46/199 (23%)

Query: 447 PRGPRGDRGSQGPPGPT----------GNKGQKGEKGEP----------GPPGPAGERGP 486
           P  P  +    G P  T          G  G+KG+KGEP          GPPGPAG   P
Sbjct: 354 PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAG---P 410

Query: 487 IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP----PGKEGLPGPQG 542
            G  GPPG +G  G  G  G    RG PG+PG  G  G PGPPG     P + G  G +G
Sbjct: 411 AGIMGPPGLQGPTGPPGDPG---DRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKG 467

Query: 543 PP------GFQGL--QGTVGEPGVPGPRGLPGLPGV---PGMPGPKGPPGPPGPSGAVVP 591
           P         Q +  Q  +   G PGP GL G PG    PG  G KG  G PGP G   P
Sbjct: 468 PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQG---P 524

Query: 592 LALQNEPTPA--PEDNGCP 608
             +Q  P P   P   G P
Sbjct: 525 RGVQGPPGPTGKPGKRGRP 543



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 23/45 (51%), Positives = 29/45 (64%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI 487
            G PGP+GP+G++GS GP G  G+ G  G  G PGPPG   +  PI
Sbjct: 1465 GLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPI 1509


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  169 bits (428), Expect = 9e-42
 Identities = 86/179 (48%), Positives = 100/179 (55%), Gaps = 24/179 (13%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTG---------------------NKGQKGEKGEPGPPGPA 481
            GPPG +GP GD G +G PGP G                     +KG+ G+ G+PGPPGP+
Sbjct: 1291 GPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPS 1350

Query: 482  GERGPIGPAG---PPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLP 538
            GE GP GP G   PPG  G +G +G +G KG  G+ G PG  GP G  GP G PG EGL 
Sbjct: 1351 GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR 1410

Query: 539  GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNE 597
            G  GP G QGL G  G+ G PGP G PGLPG+ G PG KG  G PG  G + P   Q E
Sbjct: 1411 GIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE 1469



 Score =  166 bits (421), Expect = 6e-41
 Identities = 91/203 (44%), Positives = 101/203 (49%), Gaps = 45/203 (22%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP---------- 492
            GP G RGP G RGS+G  GPTG  G KG  G  GPPGP GERGP GP GP          
Sbjct: 877  GPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPP 936

Query: 493  --------PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD---------PGPPGPPGKE 535
                    PG  G +G  G QG  G  G  G  GPQGP+G+         PGPPGPPG++
Sbjct: 937  GPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQ 996

Query: 536  GLPGPQG---------PPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGP- 585
            GLPG  G         P G  G  G  G  G PG RGLPG  G PG+ G +GP GPPGP 
Sbjct: 997  GLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV 1056

Query: 586  --------SGAVVPLALQNEPTP 600
                    +G   P+ L   P P
Sbjct: 1057 GSPGERGSAGTAGPIGLPGRPGP 1079



 Score =  164 bits (414), Expect = 4e-40
 Identities = 85/177 (48%), Positives = 101/177 (57%), Gaps = 11/177 (6%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE---PGPPGPAGERGPIGPAGPPGERGGK 499
           G PGP G  G++G  G PG  G  G++G KG    PG PG  GE+G  G AG PG RG +
Sbjct: 823 GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 882

Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV- 558
           G  G +G +G+RG  GKPGP+G SG  GPPGPPG+ G  GPQGP GF G +G  G PG  
Sbjct: 883 GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 942

Query: 559 -----PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP--APEDNGCP 608
                PG RG  G  G  G PGP G  GP GP+G   P+  +  P P   P + G P
Sbjct: 943 GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLP 999



 Score =  163 bits (412), Expect = 6e-40
 Identities = 92/183 (50%), Positives = 97/183 (53%), Gaps = 33/183 (18%)

Query: 442  QGPPGPRGPRGDRGS---------------QGPPGPTGNKGQKGEKGEPGP------PGP 480
            QGPPGP G  G+RGS               QGPPGP G KG  GEKG  GP       GP
Sbjct: 1050 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1109

Query: 481  AGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP 540
             G  GP GPAG PGE G KG  G  G KGS+G  G+ GP GP G  GP G PG  G  G 
Sbjct: 1110 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGE 1169

Query: 541  QGPPGFQGL------QGTVGEPGVPGPRGLPGLPGVPGMP------GPKGPPGPPGPSGA 588
             GP G QG+      +G  G PG PGP GL GLPG PG        GP GPPGPPGP G 
Sbjct: 1170 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGP 1229

Query: 589  VVP 591
              P
Sbjct: 1230 QGP 1232



 Score =  162 bits (410), Expect = 1e-39
 Identities = 84/164 (51%), Positives = 94/164 (57%), Gaps = 12/164 (7%)

Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGP 492
           + F  L G PG +G RG+RG QGPPGP G+ G +GE GE GP   PG AG RG +GP G 
Sbjct: 600 RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGT 659

Query: 493 PGE---------RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGP 543
           PG           G  G KG+ GP+G  G PG+ G  GP G PGP GP G  G  GPQG 
Sbjct: 660 PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 719

Query: 544 PGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           PG  GL G  G PG PG  G  G  G  G PGP+GP G PGP G
Sbjct: 720 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRG 763



 Score =  162 bits (410), Expect = 1e-39
 Identities = 90/197 (45%), Positives = 100/197 (50%), Gaps = 36/197 (18%)

Query: 443  GPPGPRGPRGDRGSQGPPGP---------TGNKGQKGEKGEPGPP------GPAGERGPI 487
            GPPGPRGP+G  G+ GP GP          G KG+ GE G PGPP      GP GERG  
Sbjct: 1222 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1281

Query: 488  GPAGPPGER---GGKGSKGSQGPKGS---------RGSPGKPGP---------QGPSGDP 526
            G AGPPG     G KG  G  GPKG+          G PG+PGP         +G  GDP
Sbjct: 1282 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDP 1341

Query: 527  GPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPS 586
            G PGPPG  G  GP GPPG +G  G  G  G  G +G  G  G  G PG  GP GP GP+
Sbjct: 1342 GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPA 1401

Query: 587  GAVVPLALQNEPTPAPE 603
            G   P  L+  P P  E
Sbjct: 1402 GKPGPEGLRGIPGPVGE 1418



 Score =  160 bits (406), Expect = 3e-39
 Identities = 86/173 (49%), Positives = 95/173 (54%), Gaps = 11/173 (6%)

Query: 443  GPPGPRG---PRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---PAGPPGER 496
            GPPG  G   P+G+RG +G  GP G  G  G KG PG  GP G  GP+G     GPPGE 
Sbjct: 1264 GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEP 1323

Query: 497  GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
            G  G  G  G KG  G PG+PGP GPSG+ GPPGPPGK G PG  G  G QG +G  GE 
Sbjct: 1324 GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEA 1383

Query: 557  GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609
            G  GP   PG  G  G  GP G PGP G  G   P+  Q  P  A +D   PP
Sbjct: 1384 GAEGP---PGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDG--PP 1431



 Score =  159 bits (403), Expect = 7e-39
 Identities = 82/170 (48%), Positives = 98/170 (57%), Gaps = 7/170 (4%)

Query: 443  GPPGPRG---PRGDRGSQGPPGPTG---NKGQKGEKGEPGPPGPAGERGPIGPAGPPGER 496
            GPPGP G   P G  G +GPPG  G    +G+KG KGE G  GP G+ GP+GP GP G+ 
Sbjct: 1345 GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1404

Query: 497  GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
            G +G +G  GP G +G PG  G  GP G  GPPG PG +G PG +G  G  GL G +G P
Sbjct: 1405 GPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPP 1464

Query: 557  GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP-APEDN 605
            G  G +G  GLPG  G PG KG  G PGP+G + P      P P  P+ N
Sbjct: 1465 GEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN 1514



 Score =  158 bits (400), Expect = 2e-38
 Identities = 85/175 (48%), Positives = 96/175 (54%), Gaps = 18/175 (10%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERG--- 497
           L+GPPGP G  G     GP G  G+ G KGE G+PGP GP G +GP GP G PG+RG   
Sbjct: 527 LRGPPGPMGLTG---RPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPG 583

Query: 498 ---GKGSKGSQGPKGSRGS------PGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG 548
              G+G  G  G KG RG       PG  G +G  G  GPPGPPG +G+ G  G  G +G
Sbjct: 584 ADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRG 643

Query: 549 LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPP---GPSGAVVPLALQNEPTP 600
           L G  G  G+ GPRG PG PG PGM G  GPPGP    GP G   P   Q  P P
Sbjct: 644 LPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 698



 Score =  158 bits (399), Expect = 2e-38
 Identities = 81/158 (51%), Positives = 95/158 (60%), Gaps = 15/158 (9%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG------ERGPIGPAGPPGE 495
           +G PG  G +GDRG  G PG  G+KG +GE+G  GPPGP G      E G IGP G PGE
Sbjct: 588 RGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGE 647

Query: 496 RGGKGSKGSQGPKGSRGSPGK------PGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGL 549
            G +G  G +G  G+ G PG       PGP+G  G  G PGPPG++G PGPQG P   G 
Sbjct: 648 AGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLP---GP 704

Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           QG +G PG  GP+G PGL G+PG  GP G PG  G SG
Sbjct: 705 QGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSG 742



 Score =  157 bits (398), Expect = 3e-38
 Identities = 78/153 (50%), Positives = 89/153 (58%), Gaps = 6/153 (3%)

Query: 441 LQGPPGPRGPRGDR------GSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG 494
           +QGPPGP G  G R      G +G PG  G KG +G  G PG PG  G RG  GP GPPG
Sbjct: 566 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 625

Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVG 554
             G  G +G  G  G RG PG+ GP+G  G  G PG PG+ G+ G  GPPG +G  G  G
Sbjct: 626 PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG 685

Query: 555 EPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           EPG PG +G PG  G+PG  GP GPPG  GP G
Sbjct: 686 EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQG 718



 Score =  156 bits (395), Expect = 6e-38
 Identities = 86/187 (45%), Positives = 96/187 (51%), Gaps = 36/187 (19%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAG------PPG 494
            L GP GP G  G+ G +G  G  G KG KG+KGE GPPGP G +GP+G  G       PG
Sbjct: 1112 LPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPG 1171

Query: 495  ERGGKGSKGSQGPKGSRGSPGKPGP---------------------QGPSGDPGPPGPPG 533
             RG +G  G +G +G+RG PG PGP                      GP G PGP GP G
Sbjct: 1172 PRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQG 1231

Query: 534  KEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPK---------GPPGPPG 584
              G  GPQGPPG  G  G VGE G PG  G PG PG  G+ GPK         GPPG  G
Sbjct: 1232 PNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAG 1291

Query: 585  PSGAVVP 591
            P GA  P
Sbjct: 1292 PPGAKGP 1298



 Score =  154 bits (390), Expect = 2e-37
 Identities = 87/188 (46%), Positives = 95/188 (50%), Gaps = 30/188 (15%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPG---PAGERGPIGPAGPPGERG 497
            L G PG +GP+G  G  G PG  G KG +G  G+PGP G   P G RG  G  GP G+ G
Sbjct: 842  LPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG 901

Query: 498  GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGP---PGPPGKEGLP---------------- 538
             KG+ G  GP G  G  G  GPQGP G PGP   PGPPGK+GLP                
Sbjct: 902  PKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 961

Query: 539  --------GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVV 590
                    GPQGP G  G  G  G PG PGP G  GLPG  G  G KG PGP G SG   
Sbjct: 962  PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDG 1021

Query: 591  PLALQNEP 598
            P  L+  P
Sbjct: 1022 PAGLRGFP 1029



 Score =  154 bits (390), Expect = 2e-37
 Identities = 80/172 (46%), Positives = 90/172 (52%), Gaps = 4/172 (2%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
            +G  G  GP G  G QG PGP G KG+ G+ G  GPPGP G RGP GP G  G +G  GS
Sbjct: 1185 EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGS 1244

Query: 502  KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGP 561
             GS G  G +G PG+ G  GP G+ G  GP G+ G  G  GPPG  G  G  G PG  GP
Sbjct: 1245 VGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGP 1304

Query: 562  RGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP----TPAPEDNGCPP 609
            +G PG  G PG PGP G PGP G  G         +P     P P     PP
Sbjct: 1305 KGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1356



 Score =  153 bits (387), Expect = 5e-37
 Identities = 80/162 (49%), Positives = 87/162 (53%), Gaps = 18/162 (11%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGP------------AGERGPIG 488
            L GPPG +G  GD G  GPPGP G +G +G  G  GP GP             GE G  G
Sbjct: 1202 LPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAG 1261

Query: 489  PAGPPGERGGKGSKGSQGPKGSRGSP---GKPGPQGPSGDPGPPGPPGKEGLPGPQGPPG 545
              GPPGE G  G KG +G KG  G P   G PG +GP GD GP G PG  G PG  GPP 
Sbjct: 1262 NPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP- 1320

Query: 546  FQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
              G  G  G+ GV G +G  G PG PG PGP G  GPPGP G
Sbjct: 1321 --GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPG 1360



 Score =  152 bits (385), Expect = 8e-37
 Identities = 84/173 (48%), Positives = 90/173 (52%), Gaps = 16/173 (9%)

Query: 448 RGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGP 507
           RGP G  G  G PGP G  G  G KGE G PGP G RG  GP GP G+ G +G  G+ G 
Sbjct: 528 RGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGG 587

Query: 508 KGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLP-- 565
           +G  G PG  G +G  G PG PG  G  G  GPQGPPG  G  G  GE G  GPRGLP  
Sbjct: 588 RGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGE 647

Query: 566 ----------GLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
                     G PG PG PG  G  GPPGP G + P   Q EP P P   G P
Sbjct: 648 AGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGP---QGEPGP-PGQQGNP 696



 Score =  152 bits (385), Expect = 8e-37
 Identities = 86/186 (46%), Positives = 96/186 (51%), Gaps = 26/186 (13%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---PAGPPGERGG 498
            +G PGP GP G +G  GPPG  G  G  G  G PGPPGP G +GP G   P GPPG  G 
Sbjct: 1188 RGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGS 1247

Query: 499  KGSKGSQGPKGSRGSPGKPG------PQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552
             G  G +G  G  G+PG PG      P+G  G+ G  GPPG  G PG +GPPG  G +G 
Sbjct: 1248 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1307

Query: 553  ---VGEPGVPGPRGLPGLPGVPGMPGPK------GPPGPPGPSGAVVPLALQNEPTPAPE 603
               VG PG PGP G PG  G  G+ G K      G PGPPGPSG   P        P P 
Sbjct: 1308 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGP--------PGPP 1359

Query: 604  DNGCPP 609
                PP
Sbjct: 1360 GKRGPP 1365



 Score =  150 bits (379), Expect = 4e-36
 Identities = 86/187 (45%), Positives = 97/187 (51%), Gaps = 36/187 (19%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKG------QKGEKGEPGPPGPAGERGPIGPAGPPGE 495
            QGP G  GP G+RG  GPPGP G +G      ++G KG+PGP G +G+ GP G  G PGE
Sbjct: 972  QGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGE 1031

Query: 496  RGG---------KGSKGSQGPKGSRGSPGK------------PGPQGPSGDPGPPGPPGK 534
            RG          KG +G QGP G  GSPG+            PG  GP G PGP G  G 
Sbjct: 1032 RGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGA 1091

Query: 535  EGLPGPQGPPGFQGLQGTVGEPGVPGPRGLP---------GLPGVPGMPGPKGPPGPPGP 585
             G  GPQGP G  G+QG VG PG  GP G P         G PG  G  G KG  GPPGP
Sbjct: 1092 PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGP 1151

Query: 586  SGAVVPL 592
             G   P+
Sbjct: 1152 PGLQGPV 1158



 Score =  149 bits (376), Expect = 9e-36
 Identities = 81/173 (46%), Positives = 93/173 (53%), Gaps = 5/173 (2%)

Query: 439  TILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498
            T  QG  GP GP G  G QGP G TG  G++G  G PGPPG  G  G  G  G  G+ G 
Sbjct: 954  TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 1013

Query: 499  KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT---VGE 555
            +G  G  GP G RG PG+ G  G  G PG  G  G +G PGP G PG +G  GT   +G 
Sbjct: 1014 QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGL 1073

Query: 556  PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA--PEDNG 606
            PG PGP+G PG  G  G PG KGP GP G  G   P+ L     PA  P ++G
Sbjct: 1074 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG 1126



 Score =  145 bits (365), Expect = 2e-34
 Identities = 79/186 (42%), Positives = 98/186 (52%), Gaps = 22/186 (11%)

Query: 443  GPPGPRGP---------------RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI 487
            GPPG RGP               +G+ G++GPPG TG  G +G  G+PGP G  G  GP+
Sbjct: 1357 GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV 1416

Query: 488  GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDP---GPPGPPGKEGLPGPQGPP 544
            G  G PG  G  G  G  GP G  G  G PG +G  G P   G  GPPG++G  G +G P
Sbjct: 1417 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1476

Query: 545  GFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP-TPAPE 603
            G QG  G  G+ G+PGP G  G PG PG+PGP+GP G  G +G   P   + +   P P 
Sbjct: 1477 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTG---PAGQKGDSGLPGPP 1533

Query: 604  DNGCPP 609
             +  PP
Sbjct: 1534 GSPGPP 1539



 Score =  144 bits (364), Expect = 2e-34
 Identities = 84/196 (42%), Positives = 92/196 (46%), Gaps = 51/196 (26%)

Query: 443 GPPGPRGP------RGDRGSQGPPGPTGNKGQKGE------------------------K 472
           GPPGP+GP      RG +G+ G  G  G+KG+KGE                        +
Sbjct: 748 GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 807

Query: 473 GEPGPPGPAGERGPIGPAGPPGERGGKGS---------KGSQGPKGSRGSPGKPGPQ--- 520
           GE GP GP G  GP G  GP G+ G KG           G QGPKGS G PG PG     
Sbjct: 808 GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 867

Query: 521 ---------GPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVP 571
                    GP G  GP GP G  G  GP G PG +G  G  G PG PG RG  G  G  
Sbjct: 868 GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPV 927

Query: 572 GMPGPKGPPGPPGPSG 587
           G PGPKGPPGPPG  G
Sbjct: 928 GFPGPKGPPGPPGKDG 943



 Score =  144 bits (364), Expect = 2e-34
 Identities = 73/145 (50%), Positives = 86/145 (59%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            GP G RG  G+RG  G  G  G KG +G +G PGP G  GERG  G AGP G  G  G +
Sbjct: 1021 GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQ 1080

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
            G  GP G +G+PG+ GPQGP+G  G  GP G  G  GP G PG  G +G +GEPG  G +
Sbjct: 1081 GPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSK 1140

Query: 563  GLPGLPGVPGMPGPKGPPGPPGPSG 587
            G  G  G PG PG +GP G PG +G
Sbjct: 1141 GDKGENGPPGPPGLQGPVGAPGIAG 1165



 Score =  144 bits (363), Expect = 3e-34
 Identities = 79/165 (47%), Positives = 91/165 (55%), Gaps = 15/165 (9%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGPPGERGG 498
           +G PG  G  G  G  GPPGP GN G +GE G PG    PGP G  GP GP GPPGE+G 
Sbjct: 657 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 716

Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDP---GPPGPPGKEGLPGP---QGPPGFQGLQGT 552
           +G  G  G  G+ G PG PG +G SG+    GPPGP G  G PGP   +G  G +GL+G+
Sbjct: 717 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 776

Query: 553 VGE------PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
            GE      PG  G  GL G  G  G  GP+G  GP GP G   P
Sbjct: 777 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP 821



 Score =  144 bits (363), Expect = 3e-34
 Identities = 84/203 (41%), Positives = 98/203 (48%), Gaps = 36/203 (17%)

Query: 443 GPPGPRGPRGDRG------SQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGER 496
           GPPG +GP+G  G      + GPPG  G +GQ GEKG  GPPGP G  G  GP G  G  
Sbjct: 709 GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGAD 768

Query: 497 GGKGSKGSQGPKGSRGSPG---------------------KPGPQGPSGDPGPPGPPG-- 533
           G +G KGS+G KG  G PG                     + GP+GP G  GP G PG  
Sbjct: 769 GVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPS 828

Query: 534 -------KEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPS 586
                  K G+PG  G PG QG +G+ G PG PG  G  G  GV G PGP+G  GP GP 
Sbjct: 829 GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPR 888

Query: 587 GAVVPLALQNEPTPAPEDNGCPP 609
           G+        +P P     G  P
Sbjct: 889 GSRGARGPTGKPGPKGTSGGDGP 911



 Score =  144 bits (362), Expect = 4e-34
 Identities = 84/189 (44%), Positives = 97/189 (51%), Gaps = 32/189 (16%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
            L G  G  G +G  G QGPPGP G+ G++G  G  GP G  G  GP GP GP GE+G  G
Sbjct: 1034 LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1093

Query: 501  SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP---PGKEGLPGPQGPPGFQGLQGTVGEPG 557
             KG QGP G      + G QGP G PGP GP   PG++G  G  G PG +G +G  GE G
Sbjct: 1094 EKGPQGPAG------RDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1147

Query: 558  VPGPRGLPGLPGVPGMPGPKGPPGP------------------PGPSGAVVPLALQNEPT 599
             PGP GL G  G PG+ G  G PGP                  PGP G   P+ LQ  P 
Sbjct: 1148 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG---PIGLQGLPG 1204

Query: 600  PAPE--DNG 606
            P  E  +NG
Sbjct: 1205 PPGEKGENG 1213



 Score =  142 bits (359), Expect = 9e-34
 Identities = 83/193 (43%), Positives = 96/193 (49%), Gaps = 45/193 (23%)

Query: 440 ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP----PGE 495
           +++GPPGP GP G  G  G  GPTG  G  G++G PG PG  G  G  GP G     P  
Sbjct: 439 LVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFR 498

Query: 496 RGGKGSKGS--------------------QGPKGSRGSPGKPGP---------QGPSGDP 526
            GG GSKG                     +GP G  G  G+PGP         +G SGDP
Sbjct: 499 YGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDP 558

Query: 527 GPPGPPGKEGLPGPQGPPGFQGL------QGTVGEPGVPGPRGLPGLPGVP------GMP 574
           GP GP G +G PGP G PG +G       +G  GEPG  G RG  GLPG+P      G  
Sbjct: 559 GPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER 618

Query: 575 GPKGPPGPPGPSG 587
           GP+GPPGPPG  G
Sbjct: 619 GPQGPPGPPGDDG 631



 Score =  142 bits (359), Expect = 9e-34
 Identities = 77/158 (48%), Positives = 88/158 (55%), Gaps = 9/158 (5%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
            +GPPG  GP G +G  G PGP G +G  G  GE G PG AG+ GP GP GPPG  G KG 
Sbjct: 1386 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD 1445

Query: 502  KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGP---PGFQGLQGTVGEPGV 558
             GS+G KG  G  G  GP G  G+ G  G PG +G PG +G    PG  G  G  G PG+
Sbjct: 1446 PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL 1505

Query: 559  PGPRGLPGLPGVPGMPGPK------GPPGPPGPSGAVV 590
            PGP+G  G  G  G  G K      GPPG PGP G V+
Sbjct: 1506 PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVI 1543



 Score =  142 bits (358), Expect = 1e-33
 Identities = 81/172 (47%), Positives = 89/172 (51%), Gaps = 12/172 (6%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
            LQGP G  G  G  G  GP G  G  GQKG++G  G PGP G  G  G  GPPGE+   G
Sbjct: 1154 LQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK---G 1210

Query: 501  SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL---PGPQGPPGFQGLQGTVGEPG 557
              G  GP G  G PG  GPQGP+G  GP GPPG  G     G +G PG  G  G  GE G
Sbjct: 1211 ENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1270

Query: 558  VPGP------RGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPE 603
            V GP      +G  G PG  G PG KGPPG  GP G   P+    +P P  E
Sbjct: 1271 VGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1322



 Score =  141 bits (355), Expect = 2e-33
 Identities = 78/173 (45%), Positives = 93/173 (53%), Gaps = 15/173 (8%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGP---AGPPGERG 497
           + GPPGP+G  G +G  GPPG  GN G +G  G  GP GP GE+GP G    AG PG  G
Sbjct: 671 VDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADG 730

Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGP---------PGFQ- 547
             G  G +G  G +G+ G PGPQGP G PGP G  G +G+ G +G          PGF+ 
Sbjct: 731 PPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKG 790

Query: 548 --GLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598
             GL+G  GE G  GPRG  G  G  G  GP G PGP G +G    L +   P
Sbjct: 791 DMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLP 843



 Score =  136 bits (343), Expect = 6e-32
 Identities = 72/142 (50%), Positives = 83/142 (58%), Gaps = 6/142 (4%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
            + GP G +G  G  G  GPPGP G  G  G KG+PG  G  G  G IG  GPPGE+G KG
Sbjct: 1412 IPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKG 1471

Query: 501  SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPG 560
             +G  G +GS G+ G  G  GP+G  GPPGPP   GLPGPQGP   +G +G+ G  G  G
Sbjct: 1472 DRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP---GLPGPQGP---KGNKGSTGPAGQKG 1525

Query: 561  PRGLPGLPGVPGMPGPKGPPGP 582
              GLPG PG PG PG    P P
Sbjct: 1526 DSGLPGPPGSPGPPGEVIQPLP 1547



 Score = 99.8 bits (247), Expect = 8e-21
 Identities = 76/199 (38%), Positives = 86/199 (43%), Gaps = 46/199 (23%)

Query: 447 PRGPRGDRGSQGPPGPT----------GNKGQKGEKGEP----------GPPGPAGERGP 486
           P  P  +    G P  T          G  G+KG+KGEP          GPPGPAG   P
Sbjct: 393 PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAG---P 449

Query: 487 IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP----PGKEGLPGPQG 542
            G  GPPG +G  G  G  G    RG PG+PG  G  G PGPPG     P + G  G +G
Sbjct: 450 AGIMGPPGLQGPTGPPGDPG---DRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKG 506

Query: 543 PP------GFQGL--QGTVGEPGVPGPRGLPGLPGV---PGMPGPKGPPGPPGPSGAVVP 591
           P         Q +  Q  +   G PGP GL G PG    PG  G KG  G PGP G   P
Sbjct: 507 PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQG---P 563

Query: 592 LALQNEPTPA--PEDNGCP 608
             +Q  P P   P   G P
Sbjct: 564 RGVQGPPGPTGKPGKRGRP 582



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 23/45 (51%), Positives = 29/45 (64%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI 487
            G PGP+GP+G++GS GP G  G+ G  G  G PGPPG   +  PI
Sbjct: 1504 GLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPI 1548


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score =  168 bits (426), Expect = 1e-41
 Identities = 89/185 (48%), Positives = 106/185 (57%), Gaps = 22/185 (11%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG------- 494
           +G  G RG +G+RG  G PG  G+ GQ+G  G  G  GP GE+G +GPAGPPG       
Sbjct: 592 RGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQ 651

Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPG------PQGPPGFQG 548
           + G KG +G+ GP+G +G+PG PG +GP G  G  GPPG +GL G      P G PG  G
Sbjct: 652 QEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLG 711

Query: 549 LQGTVGEPGVPGPRG------LPG---LPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPT 599
           LQG  G PGVPGP G      LPG    PG PG PGP GPPG  GP+G   P   + EP 
Sbjct: 712 LQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPG 771

Query: 600 PAPED 604
              ED
Sbjct: 772 ERGED 776



 Score =  159 bits (403), Expect = 7e-39
 Identities = 85/174 (48%), Positives = 98/174 (56%), Gaps = 13/174 (7%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            GPPG  G  G +G +G PG  G +G +G+KGE GPPG  G   P G AGP G +G +G+ 
Sbjct: 1120 GPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPG---PPGIAGPQGSQGERGAD 1176

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
            G  G KG +G PG PG  GP   PG PGPPG +G+ G  GPPG QG  G  G PG  GP 
Sbjct: 1177 GEVGQKGDQGHPGVPGFMGP---PGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPS 1233

Query: 563  GLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP-TPAPEDNGCPPHWKNFT 615
            GLPG+PG  G  G  G PGPPG  G         EP  P PE    PP +K  T
Sbjct: 1234 GLPGIPGEEGKEGRDGKPGPPGEPGKA------GEPGLPGPEGARGPPGFKGHT 1281



 Score =  157 bits (397), Expect = 3e-38
 Identities = 82/176 (46%), Positives = 99/176 (56%), Gaps = 30/176 (17%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPG---PAGERGPIGPAGPPGERGG 498
            +GPPG +G  GD G+ GP G +G  G  G++G PG  G   P G +GP GP GPPG+ G 
Sbjct: 1272 RGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGS 1331

Query: 499  KGSKGSQGP---------KGSRGSPGKP---GPQGPSGDPGPPGPPGKEGLPGPQGPPGF 546
             GS G  GP         KG  GSPG P   GP+GP G+PG  G PGKEG+PG  G PGF
Sbjct: 1332 PGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGF 1391

Query: 547  QGL---------------QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
            +G                +G  G+PG+PG +G  GL G  G+PG  GP GPPGP G
Sbjct: 1392 KGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPG 1447



 Score =  155 bits (391), Expect = 2e-37
 Identities = 85/186 (45%), Positives = 97/186 (52%), Gaps = 28/186 (15%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKG------EPGPPGPAGERGPIGPAGPPG 494
            L GPPG  GP+G +G +G  G  G KG +G  G       PG PGP G  G  G AGPPG
Sbjct: 1157 LPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPG 1216

Query: 495  ERGGKGSKGSQGPKGSRGSPGKPGPQGPSG---DPGPPGPPGKEG---LPGPQGPPGFQG 548
             +G  G +G  GP+G  G PG PG +G  G    PGPPG PGK G   LPGP+G  G  G
Sbjct: 1217 IQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPG 1276

Query: 549  LQGTVGEPGVPGPR------GLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAP 602
             +G  G+ G PGPR      GLPG  G+PG  G  GP GP GP G          P   P
Sbjct: 1277 FKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQG----------PRGPP 1326

Query: 603  EDNGCP 608
              NG P
Sbjct: 1327 GKNGSP 1332



 Score =  152 bits (385), Expect = 8e-37
 Identities = 80/158 (50%), Positives = 93/158 (58%), Gaps = 12/158 (7%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
           QG PGP G RG  G +G  GP G +G +G+KG+ GPPG  G  G  GP GPPG  G  G 
Sbjct: 668 QGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGP 727

Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDP------GPPGPPGKEGLPGPQGP---PGFQGLQGT 552
            GS G  G  G PGKPGP GP+G P      GPPGPPG +G PG +G    PG  GL+G 
Sbjct: 728 GGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGE 787

Query: 553 VGEPGV---PGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           +GE G+   PG +G  GLPG PG PG +G  G  G  G
Sbjct: 788 IGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKG 825



 Score =  151 bits (381), Expect = 2e-36
 Identities = 79/157 (50%), Positives = 85/157 (54%), Gaps = 12/157 (7%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG---------PPGPAGERGPIGPAGPP 493
           GPPG RGP G  G  GPPG  G +G+KG+ G PG         PPGP G  GP GP G P
Sbjct: 672 GPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSP 731

Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGK---EGLPGPQGPPGFQGLQ 550
           G  G  G  G  GP G  G PGK GP GP G PG  G PG+   +GLPG  G  G  G Q
Sbjct: 732 GLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQ 791

Query: 551 GTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           G  G PG  G  GLPG PG PG+ G KG  G  G  G
Sbjct: 792 GLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELG 828



 Score =  150 bits (380), Expect = 3e-36
 Identities = 78/147 (53%), Positives = 85/147 (57%), Gaps = 3/147 (2%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            GPPG  GP G  G QG  G  G  G+ G+KG+ G PG  G  GP G  GPPG  G  G+ 
Sbjct: 1153 GPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAA 1212

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
            G  G +GS G  G PGPQGPSG PG PG  GKEG  G  GPP   G  G  GEPG+PGP 
Sbjct: 1213 GPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPP---GEPGKAGEPGLPGPE 1269

Query: 563  GLPGLPGVPGMPGPKGPPGPPGPSGAV 589
            G  G PG  G  G  G PGP G SGA+
Sbjct: 1270 GARGPPGFKGHTGDSGAPGPRGESGAM 1296



 Score =  149 bits (377), Expect = 7e-36
 Identities = 74/159 (46%), Positives = 92/159 (57%), Gaps = 12/159 (7%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG------PIGPAGPPG 494
            +QG PG  GP G +G  G PG  G +G++G  G+PGPPG  G+ G      P G  GPPG
Sbjct: 1217 IQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPG 1276

Query: 495  ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVG 554
             +G  G  G+ GP+G  G+ G PG +G  G  G  GP G +G  GP+GPPG  G  G+ G
Sbjct: 1277 FKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPG 1336

Query: 555  EPG---VPGPRGLPG---LPGVPGMPGPKGPPGPPGPSG 587
            EPG    PG +G  G    PG+PG  GP+GPPG PG  G
Sbjct: 1337 EPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKG 1375



 Score =  148 bits (374), Expect = 2e-35
 Identities = 80/174 (45%), Positives = 93/174 (53%), Gaps = 10/174 (5%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP---PGERGGK 499
            GPPG  G  G+ G  GP G  G  G KG  G+ G PGP GE G +G  G    PG+ G  
Sbjct: 1252 GPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDT 1311

Query: 500  GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559
            G  G QGP+G RG PGK G  G  G+PGP G PG++G  G  G PG  G  G  G PG P
Sbjct: 1312 GPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEP 1371

Query: 560  GPRGLP---GLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPPH 610
            G +G+P   G+PG PG PG KG  G PG  G   P   + +    P D G P H
Sbjct: 1372 GEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQ----PGDPGIPGH 1421



 Score =  148 bits (373), Expect = 2e-35
 Identities = 84/179 (46%), Positives = 94/179 (52%), Gaps = 34/179 (18%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTG-------NKGQKGEKGEPGP------PGPAGERGPIGP 489
           GP G  GP+G++G  GP GP G        +G KGE+G PGP      PGP G RGPIGP
Sbjct: 623 GPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGP 682

Query: 490 AG---PPGERGGKGSKGSQGP---------KGSRGSPGKPGPQGPSGDPG---------P 528
            G   PPG +G +G KG  GP         +G  G PG PGP GP G PG          
Sbjct: 683 EGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGK 742

Query: 529 PGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           PGPPG  G PG  GP G  G  GT GEPG  G  GLPG PG+ G  G +G  G PG  G
Sbjct: 743 PGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKG 801



 Score =  148 bits (373), Expect = 2e-35
 Identities = 79/175 (45%), Positives = 93/175 (53%), Gaps = 30/175 (17%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTG----------------NKGQKGEKGEPGPPGPAG---- 482
            G PG +G RG++G  GP GP G                 +G KGEKG+PG PG  G    
Sbjct: 828  GLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGR 887

Query: 483  --ERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP 540
              E GP GP GPPG +G +G+ G+ G  G+ G+PG  G  GPSG PG  G PG  G PG 
Sbjct: 888  PGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGK 947

Query: 541  QGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGP--------KGPPGPPGPSG 587
             G  G +G  G  G PG  GPRG PG PG+PG PG         +G PG PGP G
Sbjct: 948  DGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLG 1002



 Score =  147 bits (372), Expect = 3e-35
 Identities = 85/183 (46%), Positives = 95/183 (51%), Gaps = 38/183 (20%)

Query: 443 GPPGPRGPRGD-------------RGSQGPPGPTGNKGQKG------EKGEPGPPGPAGE 483
           G PGP+G +GD             +GS G PGP G  G KG      E GEPG PG  G 
Sbjct: 508 GAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGM 567

Query: 484 RGPIGPAGPPG------------ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGP--- 528
           RGP GP G PG            ERG KG++G +G +G  G PGKPG  G  G PGP   
Sbjct: 568 RGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGV 627

Query: 529 PGPPGKEGLPGPQGPPGFQG----LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPG 584
            GP G++G  GP GPPG  G     +G  GE G PGPRG  G PG PG  GP GP G  G
Sbjct: 628 AGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDG 687

Query: 585 PSG 587
           P G
Sbjct: 688 PPG 690



 Score =  146 bits (368), Expect = 8e-35
 Identities = 87/197 (44%), Positives = 93/197 (47%), Gaps = 52/197 (26%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGP---AGPPGERGG- 498
           GPPGP GP G  G  GPPGP G KG+ GE+GE G PG  G RG IG    AG PGE+G  
Sbjct: 744 GPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEA 803

Query: 499 -----------KGSKGSQGPKGSRGSPG-------------------------------K 516
                      +G KG QG KG  G PG                                
Sbjct: 804 GLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRM 863

Query: 517 PGPQGP---SGDPGPPGPPGKEGLP---GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGV 570
           PG QGP    GDPG PG PG +G P   GPQGP G  G +G  G  G PG  G PG PG 
Sbjct: 864 PGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGH 923

Query: 571 PGMPGPKGPPGPPGPSG 587
            G PGP GPPG  G  G
Sbjct: 924 VGAPGPSGPPGSVGAPG 940



 Score =  144 bits (364), Expect = 2e-34
 Identities = 76/165 (46%), Positives = 90/165 (54%), Gaps = 1/165 (0%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKG-EPGPPGPAGERGPIGPAGPPGERGGKGS 501
           GP G  GP+GD G+ GP G  G KG+KG+ G  P   G  GE+G +G  GPPG  G KG 
Sbjct: 490 GPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGM 549

Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGP 561
           +G  G  G  G PG+ G +GP G PG PGPPG+ G PG QG  G +G +G  GE G+ G 
Sbjct: 550 RGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGF 609

Query: 562 RGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNG 606
            G PG  G  G PGP G  GP G  G V P      P    +  G
Sbjct: 610 PGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEG 654



 Score =  144 bits (362), Expect = 4e-34
 Identities = 78/183 (42%), Positives = 94/183 (51%), Gaps = 36/183 (19%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKG------QKGEKGEPGPPGPAGE---------RG 485
            + G  GP G +G  G +GPPGP G  G      ++G++G  G PGP GE          G
Sbjct: 1208 IAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPG 1267

Query: 486  PIGPAGPPGERGGKGSKGSQGPKGSRGSPGKP------------------GPQGPSGDPG 527
            P G  GPPG +G  G  G+ GP+G  G+ G P                  GPQGP G PG
Sbjct: 1268 PEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPG 1327

Query: 528  PPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP---GPRGLPGLPGVPGMPGPKGPPGPPG 584
              G PG  G PGP G PG +G +G  G PG+P   GPRG PG PG  G+PG +G PG PG
Sbjct: 1328 KNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPG 1387

Query: 585  PSG 587
              G
Sbjct: 1388 EPG 1390



 Score =  143 bits (360), Expect = 7e-34
 Identities = 85/196 (43%), Positives = 97/196 (49%), Gaps = 36/196 (18%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGPPGE-- 495
            L G PG +G  G+ G QGP GP G KGQ+G  G PG    PG  G  G  GP+GPPG   
Sbjct: 878  LPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVG 937

Query: 496  ----RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPP-----GKEGLPGPQGPPGF 546
                RG  G  G +G KG+ G  G PGP GP GDPG PG P     GK+G PG +G PG 
Sbjct: 938  APGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGL 997

Query: 547  QGLQGT--------------VGEPGVPGPRGLPGLPGVP--------GMPGPKGPPGPPG 584
             G  GT              +G   V G RG PG+PG P        G+ GP GP GPPG
Sbjct: 998  PGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPG 1057

Query: 585  PSGAVVPLALQNEPTP 600
              G+     L   P P
Sbjct: 1058 DKGSPGSRGLPGFPGP 1073



 Score =  143 bits (360), Expect = 7e-34
 Identities = 76/149 (51%), Positives = 84/149 (56%), Gaps = 12/149 (8%)

Query: 442  QGPPGPRGP---RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498
            QGP GPRGP    G  GS G PGP+G  GQKG KGE G PG  G  GP GP G PGE+  
Sbjct: 1317 QGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEK-- 1374

Query: 499  KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV 558
                   G  G  G PGKPG  G  G+ G PG  G +G PG +G PG  G+ G  G  G+
Sbjct: 1375 -------GVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGL 1427

Query: 559  PGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
             GP+GLPG  G  G PGP G PG PG  G
Sbjct: 1428 MGPQGLPGENGPVGPPGPPGQPGFPGLRG 1456



 Score =  142 bits (359), Expect = 9e-34
 Identities = 74/147 (50%), Positives = 84/147 (57%), Gaps = 6/147 (4%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
           LQGPPGP G        GPPGP G+ G  GE G PG PGP G  GP G  GP G  G  G
Sbjct: 712 LQGPPGPPGV------PGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPG 765

Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPG 560
           +KG  G +G  G PGKPG +G  G+ G  G PG++G  G  G PGF G++G  G+ G  G
Sbjct: 766 TKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKG 825

Query: 561 PRGLPGLPGVPGMPGPKGPPGPPGPSG 587
             GLPGL G  G  G  GP GPPG  G
Sbjct: 826 ELGLPGLKGDRGEKGEAGPAGPPGLPG 852



 Score =  141 bits (355), Expect = 2e-33
 Identities = 85/202 (42%), Positives = 95/202 (47%), Gaps = 35/202 (17%)

Query: 432  GQLIKNFTILQGPPGPRGPRGD-----RGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP 486
            GQ +K      G PG  G RGD      G  GP GP G+KG  G +G PG PGP G  G 
Sbjct: 1020 GQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGR 1079

Query: 487  IGPAGPPGERG--GK----------------------------GSKGSQGPKGSRGSPGK 516
             G  G PGERG  GK                            G  G  G KG +G PGK
Sbjct: 1080 DGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGK 1139

Query: 517  PGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGP 576
            PG +G  G  G  GPPG  G PG  GP G QG +G  GE G  G +G PG+PG  G PG 
Sbjct: 1140 PGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGN 1199

Query: 577  KGPPGPPGPSGAVVPLALQNEP 598
             GPPG  G +GA  P  +Q  P
Sbjct: 1200 PGPPGADGIAGAAGPPGIQGSP 1221



 Score =  140 bits (353), Expect = 4e-33
 Identities = 87/217 (40%), Positives = 101/217 (46%), Gaps = 50/217 (23%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           G PGP G  G +G +G PG  G  G  GE G  GP GP G  GP G  G PG +G +G K
Sbjct: 536 GLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEK 595

Query: 503 GSQGPKGSRG------------SPGKP------GPQGPSGDPGPPGPPG-------KEGL 537
           G++G KG RG              G+P      GPQG  GD GP GPPG       +EGL
Sbjct: 596 GTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGL 655

Query: 538 PGPQGPPGFQGLQGTVGEPGV------------------------PGPRGLPGLPGVPGM 573
            G QG PG +G QG  G PG                          GP G+PGL G+ G 
Sbjct: 656 KGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGP 715

Query: 574 PGPKGPPGPPGPSGAV-VPLALQNEPTPAPEDNGCPP 609
           PGP G PGPPGP G+  +P  +     P P     PP
Sbjct: 716 PGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPP 752



 Score =  140 bits (352), Expect = 6e-33
 Identities = 83/188 (44%), Positives = 89/188 (47%), Gaps = 37/188 (19%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE---PGPPGPAGERGPIGPAGPPGERG 497
           L G PG +G  G  G+ G PG  G KG +GEKGE   PG  G  GE+G  GPAGPPG  G
Sbjct: 793 LAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPG 852

Query: 498 GKG-------SKGSQGPKGSRGSPGKPG------------PQGPSGDPGP---------- 528
                       G QGPKG +G PG PG            PQGP+G PG           
Sbjct: 853 TTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAP 912

Query: 529 -----PGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPP 583
                PG PG  G PGP GPPG  G  G  G PG  G RG  G  G  G PGP GP G P
Sbjct: 913 GAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDP 972

Query: 584 GPSGAVVP 591
           G  G   P
Sbjct: 973 GAPGLPGP 980



 Score =  137 bits (346), Expect = 3e-32
 Identities = 87/213 (40%), Positives = 99/213 (46%), Gaps = 57/213 (26%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGN--KGQKGEKGEPGPPGPAGERGPIGPA--------G 491
            +G PGP GPRGD G+ G PGP G    G+ G +G PG PGP G +   G          G
Sbjct: 960  EGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALG 1019

Query: 492  PPGERGGKGSKGSQGPKGSRGSPG-----KPGPQGPSGDPGPPGPPGKEGLPGPQGP--- 543
                +G +G+ G  G  GSRG PG      PGP GP GD G PG  G  G PGPQGP   
Sbjct: 1020 GQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGR 1079

Query: 544  ---PGFQGLQGTVGEPGV---------------------PGPRGLPGLP------GVPGM 573
               PG  G +G  G+PG+                     PGP GLPGLP      GVPG 
Sbjct: 1080 DGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGK 1139

Query: 574  PGPK---------GPPGPPGPSGAVVPLALQNE 597
            PG +         GPPG PGP G   P   Q E
Sbjct: 1140 PGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGE 1172



 Score =  135 bits (341), Expect = 1e-31
 Identities = 86/234 (36%), Positives = 102/234 (43%), Gaps = 60/234 (25%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG---------PPGPAGERGPIGPAGPP 493
            G PG +G RGD G +G  GP G KGQ G+ G PG         P G  GE GP+GP GPP
Sbjct: 1387 GEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPP 1446

Query: 494  GERGGKGSKGSQG-----------------------------PKGSRGSPGKPGPQGP-- 522
            G+ G  G +G                                P   + S G+PGP GP  
Sbjct: 1447 GQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPG 1506

Query: 523  -------SGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP-----GPRGLPGLPGV 570
                   +G  G PG PG+ GL GP GP G +G +G  G+PG P     G  G PG+PG 
Sbjct: 1507 KDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQ 1566

Query: 571  PGMPG--PKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPPHWKNFTDKCYYFS 622
            PG PG    G PG PGP G   P      P P      C P       +C YF+
Sbjct: 1567 PGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDP------SQCAYFA 1614



 Score =  134 bits (338), Expect = 2e-31
 Identities = 78/163 (47%), Positives = 87/163 (53%), Gaps = 9/163 (5%)

Query: 447 PRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP--IGPAGPPGERGGKGSKGS 504
           P G +G+ G  GP G  G KG  G  G  G PGP GE+G   IGP G  GE+G KGS G 
Sbjct: 479 PAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFG-QGEKGEKGSLGL 537

Query: 505 QGP------KGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV 558
            GP      KG RG PG+ G  G  G+ G  GP G  GLPGP G  G  GLQG  GE G 
Sbjct: 538 PGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGT 597

Query: 559 PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601
            G +G  GL G PG PG  G  G PGPSG   P   + +  PA
Sbjct: 598 RGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPA 640



 Score =  113 bits (283), Expect = 6e-25
 Identities = 65/148 (43%), Positives = 79/148 (53%), Gaps = 16/148 (10%)

Query: 425  KLVDSKHGQLIKN---FTILQGPPG-PRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGP 480
            +L+  + G+ ++    + + Q PP   +  +G  G  GPPG  G  G+ G  GEPG PG 
Sbjct: 1466 RLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQ 1525

Query: 481  AGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPG--KEGLP 538
             G  GP GP GP GERG KG  G+ G        G  G  GP G PG PG PG  K+GLP
Sbjct: 1526 GGLEGPSGPIGPKGERGAKGDPGAPG-------VGLRGEMGPPGIPGQPGEPGYAKDGLP 1578

Query: 539  GPQGPPGFQGLQGTVGEPGVPGPRGLPG 566
            G  GP   QG  G  G PG+PGP G PG
Sbjct: 1579 GIPGP---QGETGPAGHPGLPGPPGPPG 1603



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 44/153 (28%), Positives = 51/153 (33%), Gaps = 74/153 (48%)

Query: 519 PQGPSG-----DPGPPGPP--------------------------GKEGLPGPQGPPGFQ 547
           P GP       +P PP PP                          G+ G+ GP G PG +
Sbjct: 439 PSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPK 498

Query: 548 GLQGTVGEPGVPGPR-------------------------------------------GL 564
           G  G +G  G PGP+                                           G 
Sbjct: 499 GDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGE 558

Query: 565 PGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNE 597
           PGLPG  GM GP+GPPG PGP G V    LQ E
Sbjct: 559 PGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGE 591


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score =  168 bits (425), Expect = 2e-41
 Identities = 78/148 (52%), Positives = 92/148 (62%), Gaps = 3/148 (2%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           GPPGP G  G  G+ G PG  G +G+ G+KG+ G PGP G  G  GP GP G  G KG++
Sbjct: 828 GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 887

Query: 503 GSQGPKGSRGSPG---KPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559
           G+QGP G+ G PG   + GP G +G+PGPPGPPG  G  GP+G  G  G  G  GEPG+ 
Sbjct: 888 GAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQ 947

Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           GP G PG  G PG  GP G  GPPGP G
Sbjct: 948 GPAGPPGEKGEPGDDGPSGAEGPPGPQG 975



 Score =  163 bits (412), Expect = 6e-40
 Identities = 82/159 (51%), Positives = 93/159 (58%), Gaps = 12/159 (7%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
            QGP G  GP+G RG+QGPPG T   G  G  G  GPPG  G  GP GP GP G+ G KG+
Sbjct: 875  QGPTGVTGPKGARGAQGPPGAT---GFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA 931

Query: 502  KGSQGPKGSRGSPGKPGPQGP---SGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGE--- 555
            +G  GP G  G PG  GP GP    G+PG  GP G EG PGPQG  G +G+ G  G+   
Sbjct: 932  RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGE 991

Query: 556  ---PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
               PG+PGP G PG  G PG  G +GPPGP GP G   P
Sbjct: 992  RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGP 1030



 Score =  161 bits (408), Expect = 2e-39
 Identities = 83/165 (50%), Positives = 92/165 (55%), Gaps = 9/165 (5%)

Query: 443 GPPGPRGPRGDRGSQGPPGP---TGNKGQKGEKGEPGPPG------PAGERGPIGPAGPP 493
           GPPGP+G RG  G  G PGP    G  G+ GEKG PG PG        GE G  GP GP 
Sbjct: 588 GPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPA 647

Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553
           G  G +G +G+ GP G +G PG PGP G  G PG  G PG+ G PG  GP G +G  G  
Sbjct: 648 GPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGER 707

Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598
           G PG  G +G  GLPG PG  GPKG  GP GP GA  P  LQ  P
Sbjct: 708 GSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMP 752



 Score =  160 bits (405), Expect = 4e-39
 Identities = 79/160 (49%), Positives = 95/160 (59%), Gaps = 15/160 (9%)

Query: 443 GPPGPRGPRGDRGSQG------------PPGPTGNKGQKGEKGEPGPPGPAGERGPIGPA 490
           GPPGP GP G+RG QG            PPGP G  G+ G++G PG  G  G  GP G  
Sbjct: 642 GPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGER 701

Query: 491 GPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPG---PPGKEGLPGPQGPPGFQ 547
           G PGERG  G++G QGP+G  G+PG  GP+G SG  GPPG   PPG +G+PG +G  G  
Sbjct: 702 GFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIA 761

Query: 548 GLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           G +G  G+ G  GP G PG  G  G+ GP GPPGP G +G
Sbjct: 762 GPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANG 801



 Score =  159 bits (403), Expect = 7e-39
 Identities = 84/174 (48%), Positives = 93/174 (53%), Gaps = 15/174 (8%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           G PGP GPRG  G +G  GP G  G +G  G+PGP GP G   P+GPAG PG  G  G+K
Sbjct: 318 GSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPG---PVGPAGGPGFPGAPGAK 374

Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT---VGEPGVP 559
           G  GP G+RG  G  GP+G  G PG PGP G  G PG  G PG +G  G     G PG P
Sbjct: 375 GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP 434

Query: 560 GPRGLPGLPGVPGMPGPKGPPGPP---------GPSGAVVPLALQNEPTPAPED 604
           GPRG PG  G  G  GPKG  G P         GP G   P   Q  P PA E+
Sbjct: 435 GPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEE 488



 Score =  157 bits (398), Expect = 3e-38
 Identities = 86/210 (40%), Positives = 105/210 (50%), Gaps = 37/210 (17%)

Query: 435 IKNFTILQGPPGPRGP---------RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG 485
           IK+    +GPPGP+GP         RGD+G +G PGP G  G+ G  G PGPPGP G  G
Sbjct: 112 IKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPG 171

Query: 486 P---------------------------IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPG 518
           P                            GP GP G RG  G  G+ GP+G +G+PG+PG
Sbjct: 172 PPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG 231

Query: 519 PQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKG 578
             G SG  GP GPPG  G PG  G  G  G  G  G PG  G RG PG PG+PG+ G +G
Sbjct: 232 EPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRG 291

Query: 579 PPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
            PG  G  G      ++ E + +P +NG P
Sbjct: 292 YPGLDGAKGEAGAPGVKGE-SGSPGENGSP 320



 Score =  157 bits (398), Expect = 3e-38
 Identities = 86/193 (44%), Positives = 102/193 (52%), Gaps = 36/193 (18%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQ------KGE------KGEPGPPGPAGERGPIGP 489
           +GPPGP+G RG  G+ G PG  G++G       KGE      KGE G PG  G  GP+GP
Sbjct: 266 RGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP 325

Query: 490 AGPPGERGGKGSKGSQGPKGSRGSPGK---PGPQGPSGDPGPPGPPGKEGLPGPQGPPGF 546
            G PGERG  G  G+ G +G+ G PG    PGP GP+G PG PG PG +G  GP G  G 
Sbjct: 326 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 385

Query: 547 QGLQGTVGEPGVP---------------------GPRGLPGLPGVPGMPGPKGPPGPPGP 585
           +G QG  GEPG P                     G  G PG+ G PG PGP+GPPGP G 
Sbjct: 386 EGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGA 445

Query: 586 SGAVVPLALQNEP 598
           +G + P     EP
Sbjct: 446 TGPLGPKGQTGEP 458



 Score =  157 bits (396), Expect = 4e-38
 Identities = 87/182 (47%), Positives = 99/182 (54%), Gaps = 36/182 (19%)

Query: 442 QGPPGPRG---PRGDRGSQGPPGPTGNKGQKGEKGEPGP------PGPAGERGP------ 486
           +GPPGP+G   P G +G  G PG  G KG++G KGEPGP      PGPAGE G       
Sbjct: 437 RGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGE 496

Query: 487 ---IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGP------PGPPGKEGL 537
              +GP GPPGERG  G++G  G  G  G  G PG +GPSG  GP      PG PG+ GL
Sbjct: 497 PGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGL 556

Query: 538 P------------GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGP 585
           P            GPQG  G  G  G  G PG PGP+G  G PGV G PGPKG  G PG 
Sbjct: 557 PGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGK 616

Query: 586 SG 587
           +G
Sbjct: 617 AG 618



 Score =  155 bits (393), Expect = 1e-37
 Identities = 89/202 (44%), Positives = 102/202 (50%), Gaps = 35/202 (17%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG------------PPGPAGERGPIGP 489
           QG PGP G  G RG++G PG  G  G  GE+G PG            P G  GERGP G 
Sbjct: 479 QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGL 538

Query: 490 AGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPG---- 545
           AGP G  G  G  G  G  G+RG  G+PG  GP G  GP G PG++G PGP GP G    
Sbjct: 539 AGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ 598

Query: 546 -----FQGLQGTVGEPGVPGPRGLPGLPGVPGMP------GPKGPPGPPGPS------GA 588
                F G +G  GEPG  G +GLPG PG+ G+P      G  GPPGP GP+      GA
Sbjct: 599 PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 658

Query: 589 VVPLALQNEPTP--APEDNGCP 608
             P   Q  P P   P + G P
Sbjct: 659 PGPSGFQGLPGPPGPPGEGGKP 680



 Score =  155 bits (393), Expect = 1e-37
 Identities = 84/175 (48%), Positives = 96/175 (54%), Gaps = 7/175 (4%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG---PIGPAGPPGERGG 498
           QGPPG +G  G+RG+ G  GP G++G  GEKG  G PG  G RG   PIGP GP G  G 
Sbjct: 743 QGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGE 802

Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPG---PPGKEGLPGPQGPPGFQGLQGTVGE 555
           KG  G  GP GS G+ G PG +G +G PGP G   PPG +G PG +G  G  G +G  G 
Sbjct: 803 KGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGA 862

Query: 556 PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAV-VPLALQNEPTPAPEDNGCPP 609
           PG  GP G PG  G  G+ GPKG  G  GP GA   P A      P    N  PP
Sbjct: 863 PGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPP 917



 Score =  155 bits (392), Expect = 1e-37
 Identities = 77/157 (49%), Positives = 87/157 (55%), Gaps = 6/157 (3%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            G PG  GP G  G  GP G  G++G+ G +G  GP GPAG RG  GP GP G++G  G  
Sbjct: 1065 GAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEP 1124

Query: 503  GSQGPKGSRGS------PGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
            G +G KG RG       PG PGP G  G  GP GP G  G PGP GP G  G  G  G  
Sbjct: 1125 GERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPI 1184

Query: 557  GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLA 593
            G PGPRG  G  G  G PG  GPPGPPGP G  + ++
Sbjct: 1185 GPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMS 1221



 Score =  155 bits (391), Expect = 2e-37
 Identities = 83/170 (48%), Positives = 91/170 (53%), Gaps = 7/170 (4%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
           +GP G  G  G RG  GP GP G  G  GEKGE GPPGPAG  G  G  G  GE G  G 
Sbjct: 773 KGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP 832

Query: 502 KGSQGPKGSRGSPGKPGPQGPSG---DPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV 558
            G  GP G+ G PG  G QG +G   D G PGP G  G PGPQGP G  G +G  G  G 
Sbjct: 833 AGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP 892

Query: 559 PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
           PG  G PG  G  G PG  G PGPPGP G     + ++ P  A  D+G P
Sbjct: 893 PGATGFPGAAGRVGPPGSNGNPGPPGPPGP----SGKDGPKGARGDSGPP 938



 Score =  155 bits (391), Expect = 2e-37
 Identities = 85/181 (46%), Positives = 95/181 (52%), Gaps = 36/181 (19%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGER---GGK 499
            G  GP G  G+ G  GPPGP+G  G KG +G+ GPPG AGE G  GPAGPPGE+   G  
Sbjct: 903  GRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDD 962

Query: 500  GSKGSQGP------------------KGSRGSPGKPGPQ---------GPSGDPGPPGPP 532
            G  G++GP                  +G RG PG PGP          G SGD GPPGP 
Sbjct: 963  GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPV 1022

Query: 533  GKEGLPGPQGPPGFQGLQGTVGEP------GVPGPRGLPGLPGVPGMPGPKGPPGPPGPS 586
            G  GL GP G PG +G  G  G P      GV G RG  G  G PG PGP G PGP GP+
Sbjct: 1023 GPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPT 1082

Query: 587  G 587
            G
Sbjct: 1083 G 1083



 Score =  154 bits (390), Expect = 2e-37
 Identities = 83/181 (45%), Positives = 93/181 (51%), Gaps = 21/181 (11%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE------PGPPGPAGERGPIGPAGPPG 494
            L GP G  G  G  G+ GPPG  G  G KG++GE      PG PGP G  GP GP G  G
Sbjct: 1027 LTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1086

Query: 495  ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGK------------EGLPGPQG 542
            +RG  G++G  GP G  G+ G  GPQGP GD G  G PG+            +GLPGP G
Sbjct: 1087 DRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPG 1146

Query: 543  PPGFQGLQGTVGEPGV---PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPT 599
            P G QG  G  G  G    PGP G  G  G  G+PGP GPPGP G SG   P      P 
Sbjct: 1147 PSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPG 1206

Query: 600  P 600
            P
Sbjct: 1207 P 1207



 Score =  151 bits (381), Expect = 2e-36
 Identities = 78/178 (43%), Positives = 93/178 (52%), Gaps = 18/178 (10%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
           + GP G RG  G++G +G PG  G +G  G  G PGP G  GE+G +GP GP G  G +G
Sbjct: 760 IAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARG 819

Query: 501 SKGSQ------------GPKGSRGSPGKPGPQGPS---GDPGPPGPPGKEGLPGPQGPPG 545
           + G +            GP G+ G PG  G QG +   GD G PGP G  G PGPQGP G
Sbjct: 820 APGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTG 879

Query: 546 FQGLQGTVGEPGVPGPRGLPGLP---GVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP 600
             G +G  G  G PG  G PG     G PG  G  GPPGPPGPSG   P   + +  P
Sbjct: 880 VTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGP 937



 Score =  150 bits (378), Expect = 5e-36
 Identities = 80/169 (47%), Positives = 89/169 (52%), Gaps = 24/169 (14%)

Query: 440 ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499
           ++QGP GP GPRG  G  G PGP G +G  GE GEPG  GP G RGP    GPPG+ G  
Sbjct: 198 VMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGP---PGPPGKPGDD 254

Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP------PGKEGLPGPQGPPGFQGLQGTV 553
           G  G  G  G RG PG  G +G  G PG PG       PG +G  G  G PG +G  G+ 
Sbjct: 255 GEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSP 314

Query: 554 GEPGVPGPRGLPGLPGV---------------PGMPGPKGPPGPPGPSG 587
           GE G PGP G  GLPG                 G PGP GPPGP GP+G
Sbjct: 315 GENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAG 363



 Score =  149 bits (377), Expect = 7e-36
 Identities = 80/176 (45%), Positives = 94/176 (53%), Gaps = 10/176 (5%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
           +GP G +GPRG+ G+ G PGP G  G  G  G PG  G AG  G  G  G PG RG  G 
Sbjct: 383 RGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGP 442

Query: 502 KGSQGPKGSRGSPGKP------GPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGE 555
           +G+ GP G +G  G+P      G QGP G+PGP GP G  G  G +G  G +G  G VG 
Sbjct: 443 QGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGP 502

Query: 556 PGVPGPRGLP---GLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
            G PG RG P   G PG  G+ GPKG PG  GPSG   P     +P   P + G P
Sbjct: 503 IGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDP-GRPGEPGLP 557



 Score =  148 bits (373), Expect = 2e-35
 Identities = 79/169 (46%), Positives = 96/169 (56%), Gaps = 16/169 (9%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           G PGPRGP G +G+ GP GP      KG+ GEPG  G  GE+GP G  GP G +G  G  
Sbjct: 432 GFPGPRGPPGPQGATGPLGP------KGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA 485

Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGP---PGKEGLPGPQGPPGFQGLQGTVGEPGVP 559
           G +G +G+RG PG  GP GP G+ G PG    PG++GL GP+G PG +G  G  G  G  
Sbjct: 486 GEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGAN 545

Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
           G  G PG PG+PG  G  G PG  GP G V        P+ AP ++G P
Sbjct: 546 GDPGRPGEPGLPGARGLTGRPGDAGPQGKV-------GPSGAPGEDGRP 587



 Score =  147 bits (372), Expect = 3e-35
 Identities = 74/154 (48%), Positives = 85/154 (55%), Gaps = 22/154 (14%)

Query: 456 SQGPPGPTGNKGQKGE-KGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSP 514
           + G PGP G KG+ G+ K   GP GP G +GP G  GP G+RG KG KG+ GP+G  G P
Sbjct: 96  ASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 155

Query: 515 GKPGPQGPSGDPGPPGPPGKEG---------------------LPGPQGPPGFQGLQGTV 553
           G PG  GP G PGPPGPPG  G                     + GP GP G +G  G  
Sbjct: 156 GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 215

Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           G PG  G +G PG PG PG+ GP GP GPPGP G
Sbjct: 216 GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPG 249



 Score =  147 bits (371), Expect = 3e-35
 Identities = 77/172 (44%), Positives = 92/172 (53%), Gaps = 7/172 (4%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           GP G  GP G  G+QGPPG  G  G++G  G  GP G  G+ G  GP G PG+ GG+G  
Sbjct: 729 GPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLT 788

Query: 503 GS---QGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559
           G     GP G+ G  G+ GP GP+G  G  G PG+ G  GP GP GF G  G  G+PG  
Sbjct: 789 GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAK 848

Query: 560 GPRGLPGLPGVPGMPGPKGP---PGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
           G +G  G  G  G PGP+GP   PGP GP+G   P   +    P P   G P
Sbjct: 849 GEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP-PGATGFP 899



 Score =  146 bits (369), Expect = 6e-35
 Identities = 79/175 (45%), Positives = 91/175 (52%), Gaps = 8/175 (4%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
            QG PG  G RG  G  GPPG TG  G+ G +G PG  GP G  G  G  G  GE G  G+
Sbjct: 1007 QGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGA 1066

Query: 502  KGSQGPKGSRGSPGKPGPQGPSGDPG------PPGPPGKEGLPGPQGPPGFQGLQGTVGE 555
             G+ GP GS G  G  G QG  G+ G      P GP G  G+ GPQGP G +G  G  GE
Sbjct: 1067 PGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGE 1126

Query: 556  PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPED--NGCP 608
             G+ G RG  GL G+PG PGP G  G  GP+G   P        P+ +D  NG P
Sbjct: 1127 RGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIP 1181



 Score =  146 bits (368), Expect = 8e-35
 Identities = 78/162 (48%), Positives = 86/162 (53%), Gaps = 9/162 (5%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           G PG RG  G  G  GP G  G  G  GE G PGPPGP G RG  G  G PG +G  G  
Sbjct: 555 GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEP 614

Query: 503 GSQGPKGS------RGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
           G  G KG       RG PGK G  G +G PGP GP G+ G  G  GP GFQGL G  G P
Sbjct: 615 GKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPP 674

Query: 557 GV---PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQ 595
           G    PG +G+PG  G PG+ GP+G  G PG  G+     LQ
Sbjct: 675 GEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQ 716



 Score =  145 bits (365), Expect = 2e-34
 Identities = 73/148 (49%), Positives = 86/148 (58%), Gaps = 3/148 (2%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           G PG  GPRG+RG  G  G  G +G +G +G PG PG  G +G  GPAGPPG +G  G +
Sbjct: 690 GAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQ 749

Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKE---GLPGPQGPPGFQGLQGTVGEPGVP 559
           G  G +G+ G  G  G +G  G+ GP G PGK+   GL GP GPPG  G  G  GE G P
Sbjct: 750 GMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPP 809

Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           GP G  G  G PG  G  GPPGP G +G
Sbjct: 810 GPAGSAGARGAPGERGETGPPGPAGFAG 837



 Score =  144 bits (363), Expect = 3e-34
 Identities = 74/151 (49%), Positives = 85/151 (56%), Gaps = 6/151 (3%)

Query: 443 GPPGPRGPRGDRGSQGPPG------PTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGER 496
           GPPGP GP G  G  G PG      PTG +G +G +G  G PG  G  GP G +G PG  
Sbjct: 354 GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTD 413

Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
           G  G+KGS G  G  G+PG PGP+GP G  G  GP G +G  G  G  GF+G QG  GEP
Sbjct: 414 GIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 473

Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           G  GP+G PG  G  G  G +G PG  GP G
Sbjct: 474 GPAGPQGAPGPAGEEGKRGARGEPGGVGPIG 504



 Score =  143 bits (361), Expect = 5e-34
 Identities = 81/174 (46%), Positives = 89/174 (51%), Gaps = 24/174 (13%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG--- 498
           +G PG RG  G +G QGP G  G  G  G KG  GP GP G +GP G  G PGERG    
Sbjct: 701 RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 760

Query: 499 ---KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL------PGPQGPPGFQGL 549
              KG +G  G KG  G+PGK G +G +G  GPPGP G  G       PGP G  G +G 
Sbjct: 761 AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA 820

Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPK------------GPPGPPGPSGAVVP 591
            G  GE G PGP G  G PG  G PG K            G PGP GPSGA  P
Sbjct: 821 PGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGP 874



 Score =  142 bits (358), Expect = 1e-33
 Identities = 85/201 (42%), Positives = 96/201 (47%), Gaps = 55/201 (27%)

Query: 443 GPPGPR-------------GPRGDRGSQGP---PGPTGNKGQKGEKGEPGP------PGP 480
           G PGP+             GP+G  G QGP    GP G++G KGEKG PGP      PG 
Sbjct: 98  GQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT 157

Query: 481 AGERGPIGPAGPPG-----------------ERGG-------KGSKGSQGPKGSRGSPGK 516
            G  GP GP GPPG                 E+ G       +G  G  GP+G  G  G 
Sbjct: 158 PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGA 217

Query: 517 PGPQGPSGDPGPPGPPGKEGLPGPQGPP---------GFQGLQGTVGEPGVPGPRGLPGL 567
           PGPQG  G+PG PG PG  G  GP+GPP         G  G  G  GE G PGP+G  G 
Sbjct: 218 PGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGF 277

Query: 568 PGVPGMPGPKGPPGPPGPSGA 588
           PG PG+PG KG  G PG  GA
Sbjct: 278 PGTPGLPGVKGHRGYPGLDGA 298



 Score =  137 bits (345), Expect = 4e-32
 Identities = 69/145 (47%), Positives = 81/145 (55%), Gaps = 6/145 (4%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            GPPG +G  GD G  G  GP G +G  G++G  G PG  GERG  G  GP GE G +G+ 
Sbjct: 951  GPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAP 1010

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
            G+ G +G  G  G PG  GP+G+      PG+EG PG  GPPG  G  G  G+ G  G  
Sbjct: 1011 GASGDRGPPGPVGPPGLTGPAGE------PGREGSPGADGPPGRDGAAGVKGDRGETGAV 1064

Query: 563  GLPGLPGVPGMPGPKGPPGPPGPSG 587
            G PG PG PG PGP GP G  G  G
Sbjct: 1065 GAPGAPGPPGSPGPAGPTGKQGDRG 1089



 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 60/150 (40%), Positives = 66/150 (44%), Gaps = 28/150 (18%)

Query: 477 PPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGS----RGSPGKPGPQGPSGDPGPPGPP 532
           P  P GE  PI P       G  G KG +G  G      G  G PGPQGP+G+ GP G  
Sbjct: 78  PEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDR 137

Query: 533 GKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPG----------------------- 569
           G +G  G  GP G  G  GT G PG PGP G PG PG                       
Sbjct: 138 GDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLG 197

Query: 570 -VPGMPGPKGPPGPPGPSGAVVPLALQNEP 598
            + G  GP GP GPPGP+GA  P   Q  P
Sbjct: 198 VMQGPMGPMGPRGPPGPAGAPGPQGFQGNP 227



 Score = 97.1 bits (240), Expect = 5e-20
 Identities = 47/90 (52%), Positives = 53/90 (58%), Gaps = 3/90 (3%)

Query: 436  KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGE 495
            + FT LQG PGP GP GD+G+ GP GP+   G +G  G  GP G  G  G  GP GPPG 
Sbjct: 1133 RGFTGLQGLPGPPGPSGDQGASGPAGPS---GPRGPPGPVGPSGKDGANGIPGPIGPPGP 1189

Query: 496  RGGKGSKGSQGPKGSRGSPGKPGPQGPSGD 525
            RG  G  G  GP G+ G PG PGP GP  D
Sbjct: 1190 RGRSGETGPAGPPGNPGPPGPPGPPGPGID 1219



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 21/55 (38%), Positives = 26/55 (47%), Gaps = 4/55 (7%)

Query: 554 GEPGVPGPRGLPG----LPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPED 604
           G+PG  G +G PG    + G  G PGP+GP G  GP G       +  P P   D
Sbjct: 98  GQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRD 152


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score =  168 bits (425), Expect = 2e-41
 Identities = 78/148 (52%), Positives = 92/148 (62%), Gaps = 3/148 (2%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           GPPGP G  G  G+ G PG  G +G+ G+KG+ G PGP G  G  GP GP G  G KG++
Sbjct: 759 GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 818

Query: 503 GSQGPKGSRGSPG---KPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559
           G+QGP G+ G PG   + GP G +G+PGPPGPPG  G  GP+G  G  G  G  GEPG+ 
Sbjct: 819 GAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQ 878

Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           GP G PG  G PG  GP G  GPPGP G
Sbjct: 879 GPAGPPGEKGEPGDDGPSGAEGPPGPQG 906



 Score =  163 bits (413), Expect = 5e-40
 Identities = 88/175 (50%), Positives = 97/175 (55%), Gaps = 16/175 (9%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKG---EKGEPGPPGPAGERGPIGPAGPPGERGGK 499
           GPPGP G  G++G  GPPGP G+ G +G   E+GE GPPGPAG       AGPPG  G  
Sbjct: 723 GPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGF------AGPPGADGQP 776

Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP---PGKEGLPGPQGPPGFQGLQGTVGEP 556
           G+KG QG  G +G  G PGPQGPSG PGP GP    G +G  G QGPPG  G  G  G  
Sbjct: 777 GAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRV 836

Query: 557 GVPGPRGLPGLPGVP---GMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
           G PG  G PG PG P   G  GPKG  G  GP G      LQ  P   P + G P
Sbjct: 837 GPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQG-PAGPPGEKGEP 890



 Score =  163 bits (412), Expect = 6e-40
 Identities = 82/159 (51%), Positives = 93/159 (58%), Gaps = 12/159 (7%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
           QGP G  GP+G RG+QGPPG T   G  G  G  GPPG  G  GP GP GP G+ G KG+
Sbjct: 806 QGPTGVTGPKGARGAQGPPGAT---GFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA 862

Query: 502 KGSQGPKGSRGSPGKPGPQGP---SGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGE--- 555
           +G  GP G  G PG  GP GP    G+PG  GP G EG PGPQG  G +G+ G  G+   
Sbjct: 863 RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGE 922

Query: 556 ---PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
              PG+PGP G PG  G PG  G +GPPGP GP G   P
Sbjct: 923 RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGP 961



 Score =  161 bits (408), Expect = 2e-39
 Identities = 83/165 (50%), Positives = 92/165 (55%), Gaps = 9/165 (5%)

Query: 443 GPPGPRGPRGDRGSQGPPGP---TGNKGQKGEKGEPGPPG------PAGERGPIGPAGPP 493
           GPPGP+G RG  G  G PGP    G  G+ GEKG PG PG        GE G  GP GP 
Sbjct: 519 GPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPA 578

Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553
           G  G +G +G+ GP G +G PG PGP G  G PG  G PG+ G PG  GP G +G  G  
Sbjct: 579 GPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGER 638

Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598
           G PG  G +G  GLPG PG  GPKG  GP GP GA  P  LQ  P
Sbjct: 639 GSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMP 683



 Score =  160 bits (405), Expect = 4e-39
 Identities = 79/160 (49%), Positives = 95/160 (59%), Gaps = 15/160 (9%)

Query: 443 GPPGPRGPRGDRGSQG------------PPGPTGNKGQKGEKGEPGPPGPAGERGPIGPA 490
           GPPGP GP G+RG QG            PPGP G  G+ G++G PG  G  G  GP G  
Sbjct: 573 GPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGER 632

Query: 491 GPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPG---PPGKEGLPGPQGPPGFQ 547
           G PGERG  G++G QGP+G  G+PG  GP+G SG  GPPG   PPG +G+PG +G  G  
Sbjct: 633 GFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIA 692

Query: 548 GLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           G +G  G+ G  GP G PG  G  G+ GP GPPGP G +G
Sbjct: 693 GPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANG 732



 Score =  159 bits (403), Expect = 7e-39
 Identities = 84/174 (48%), Positives = 93/174 (53%), Gaps = 15/174 (8%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           G PGP GPRG  G +G  GP G  G +G  G+PGP GP G   P+GPAG PG  G  G+K
Sbjct: 249 GSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPG---PVGPAGGPGFPGAPGAK 305

Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT---VGEPGVP 559
           G  GP G+RG  G  GP+G  G PG PGP G  G PG  G PG +G  G     G PG P
Sbjct: 306 GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP 365

Query: 560 GPRGLPGLPGVPGMPGPKGPPGPP---------GPSGAVVPLALQNEPTPAPED 604
           GPRG PG  G  G  GPKG  G P         GP G   P   Q  P PA E+
Sbjct: 366 GPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEE 419



 Score =  157 bits (398), Expect = 3e-38
 Identities = 86/210 (40%), Positives = 105/210 (50%), Gaps = 37/210 (17%)

Query: 435 IKNFTILQGPPGPRGP---------RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG 485
           IK+    +GPPGP+GP         RGD+G +G PGP G  G+ G  G PGPPGP G  G
Sbjct: 43  IKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPG 102

Query: 486 P---------------------------IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPG 518
           P                            GP GP G RG  G  G+ GP+G +G+PG+PG
Sbjct: 103 PPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG 162

Query: 519 PQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKG 578
             G SG  GP GPPG  G PG  G  G  G  G  G PG  G RG PG PG+PG+ G +G
Sbjct: 163 EPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRG 222

Query: 579 PPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
            PG  G  G      ++ E + +P +NG P
Sbjct: 223 YPGLDGAKGEAGAPGVKGE-SGSPGENGSP 251



 Score =  157 bits (398), Expect = 3e-38
 Identities = 86/193 (44%), Positives = 102/193 (52%), Gaps = 36/193 (18%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQ------KGE------KGEPGPPGPAGERGPIGP 489
           +GPPGP+G RG  G+ G PG  G++G       KGE      KGE G PG  G  GP+GP
Sbjct: 197 RGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP 256

Query: 490 AGPPGERGGKGSKGSQGPKGSRGSPGK---PGPQGPSGDPGPPGPPGKEGLPGPQGPPGF 546
            G PGERG  G  G+ G +G+ G PG    PGP GP+G PG PG PG +G  GP G  G 
Sbjct: 257 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 316

Query: 547 QGLQGTVGEPGVP---------------------GPRGLPGLPGVPGMPGPKGPPGPPGP 585
           +G QG  GEPG P                     G  G PG+ G PG PGP+GPPGP G 
Sbjct: 317 EGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGA 376

Query: 586 SGAVVPLALQNEP 598
           +G + P     EP
Sbjct: 377 TGPLGPKGQTGEP 389



 Score =  157 bits (396), Expect = 4e-38
 Identities = 87/182 (47%), Positives = 99/182 (54%), Gaps = 36/182 (19%)

Query: 442 QGPPGPRG---PRGDRGSQGPPGPTGNKGQKGEKGEPGP------PGPAGERGP------ 486
           +GPPGP+G   P G +G  G PG  G KG++G KGEPGP      PGPAGE G       
Sbjct: 368 RGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGE 427

Query: 487 ---IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGP------PGPPGKEGL 537
              +GP GPPGERG  G++G  G  G  G  G PG +GPSG  GP      PG PG+ GL
Sbjct: 428 PGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGL 487

Query: 538 P------------GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGP 585
           P            GPQG  G  G  G  G PG PGP+G  G PGV G PGPKG  G PG 
Sbjct: 488 PGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGK 547

Query: 586 SG 587
           +G
Sbjct: 548 AG 549



 Score =  155 bits (393), Expect = 1e-37
 Identities = 89/202 (44%), Positives = 102/202 (50%), Gaps = 35/202 (17%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG------------PPGPAGERGPIGP 489
           QG PGP G  G RG++G PG  G  G  GE+G PG            P G  GERGP G 
Sbjct: 410 QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGL 469

Query: 490 AGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPG---- 545
           AGP G  G  G  G  G  G+RG  G+PG  GP G  GP G PG++G PGP GP G    
Sbjct: 470 AGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ 529

Query: 546 -----FQGLQGTVGEPGVPGPRGLPGLPGVPGMP------GPKGPPGPPGPS------GA 588
                F G +G  GEPG  G +GLPG PG+ G+P      G  GPPGP GP+      GA
Sbjct: 530 PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 589

Query: 589 VVPLALQNEPTP--APEDNGCP 608
             P   Q  P P   P + G P
Sbjct: 590 PGPSGFQGLPGPPGPPGEGGKP 611



 Score =  155 bits (393), Expect = 1e-37
 Identities = 84/175 (48%), Positives = 96/175 (54%), Gaps = 7/175 (4%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG---PIGPAGPPGERGG 498
           QGPPG +G  G+RG+ G  GP G++G  GEKG  G PG  G RG   PIGP GP G  G 
Sbjct: 674 QGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGE 733

Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPG---PPGKEGLPGPQGPPGFQGLQGTVGE 555
           KG  G  GP GS G+ G PG +G +G PGP G   PPG +G PG +G  G  G +G  G 
Sbjct: 734 KGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGA 793

Query: 556 PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAV-VPLALQNEPTPAPEDNGCPP 609
           PG  GP G PG  G  G+ GPKG  G  GP GA   P A      P    N  PP
Sbjct: 794 PGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPP 848



 Score =  155 bits (392), Expect = 1e-37
 Identities = 77/157 (49%), Positives = 87/157 (55%), Gaps = 6/157 (3%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            G PG  GP G  G  GP G  G++G+ G +G  GP GPAG RG  GP GP G++G  G  
Sbjct: 996  GAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEP 1055

Query: 503  GSQGPKGSRGS------PGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
            G +G KG RG       PG PGP G  G  GP GP G  G PGP GP G  G  G  G  
Sbjct: 1056 GERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPI 1115

Query: 557  GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLA 593
            G PGPRG  G  G  G PG  GPPGPPGP G  + ++
Sbjct: 1116 GPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMS 1152



 Score =  155 bits (391), Expect = 2e-37
 Identities = 83/170 (48%), Positives = 91/170 (53%), Gaps = 7/170 (4%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
           +GP G  G  G RG  GP GP G  G  GEKGE GPPGPAG  G  G  G  GE G  G 
Sbjct: 704 KGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP 763

Query: 502 KGSQGPKGSRGSPGKPGPQGPSG---DPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV 558
            G  GP G+ G PG  G QG +G   D G PGP G  G PGPQGP G  G +G  G  G 
Sbjct: 764 AGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP 823

Query: 559 PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
           PG  G PG  G  G PG  G PGPPGP G     + ++ P  A  D+G P
Sbjct: 824 PGATGFPGAAGRVGPPGSNGNPGPPGPPGP----SGKDGPKGARGDSGPP 869



 Score =  155 bits (391), Expect = 2e-37
 Identities = 85/181 (46%), Positives = 95/181 (52%), Gaps = 36/181 (19%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGER---GGK 499
            G  GP G  G+ G  GPPGP+G  G KG +G+ GPPG AGE G  GPAGPPGE+   G  
Sbjct: 834  GRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDD 893

Query: 500  GSKGSQGP------------------KGSRGSPGKPGPQ---------GPSGDPGPPGPP 532
            G  G++GP                  +G RG PG PGP          G SGD GPPGP 
Sbjct: 894  GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPV 953

Query: 533  GKEGLPGPQGPPGFQGLQGTVGEP------GVPGPRGLPGLPGVPGMPGPKGPPGPPGPS 586
            G  GL GP G PG +G  G  G P      GV G RG  G  G PG PGP G PGP GP+
Sbjct: 954  GPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPT 1013

Query: 587  G 587
            G
Sbjct: 1014 G 1014



 Score =  154 bits (390), Expect = 2e-37
 Identities = 83/181 (45%), Positives = 93/181 (51%), Gaps = 21/181 (11%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE------PGPPGPAGERGPIGPAGPPG 494
            L GP G  G  G  G+ GPPG  G  G KG++GE      PG PGP G  GP GP G  G
Sbjct: 958  LTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1017

Query: 495  ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGK------------EGLPGPQG 542
            +RG  G++G  GP G  G+ G  GPQGP GD G  G PG+            +GLPGP G
Sbjct: 1018 DRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPG 1077

Query: 543  PPGFQGLQGTVGEPGV---PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPT 599
            P G QG  G  G  G    PGP G  G  G  G+PGP GPPGP G SG   P      P 
Sbjct: 1078 PSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPG 1137

Query: 600  P 600
            P
Sbjct: 1138 P 1138



 Score =  151 bits (381), Expect = 2e-36
 Identities = 78/178 (43%), Positives = 93/178 (52%), Gaps = 18/178 (10%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
           + GP G RG  G++G +G PG  G +G  G  G PGP G  GE+G +GP GP G  G +G
Sbjct: 691 IAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARG 750

Query: 501 SKGSQ------------GPKGSRGSPGKPGPQGPS---GDPGPPGPPGKEGLPGPQGPPG 545
           + G +            GP G+ G PG  G QG +   GD G PGP G  G PGPQGP G
Sbjct: 751 APGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTG 810

Query: 546 FQGLQGTVGEPGVPGPRGLPGLP---GVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP 600
             G +G  G  G PG  G PG     G PG  G  GPPGPPGPSG   P   + +  P
Sbjct: 811 VTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGP 868



 Score =  150 bits (378), Expect = 5e-36
 Identities = 80/169 (47%), Positives = 89/169 (52%), Gaps = 24/169 (14%)

Query: 440 ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499
           ++QGP GP GPRG  G  G PGP G +G  GE GEPG  GP G RGP    GPPG+ G  
Sbjct: 129 VMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGP---PGPPGKPGDD 185

Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP------PGKEGLPGPQGPPGFQGLQGTV 553
           G  G  G  G RG PG  G +G  G PG PG       PG +G  G  G PG +G  G+ 
Sbjct: 186 GEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSP 245

Query: 554 GEPGVPGPRGLPGLPGV---------------PGMPGPKGPPGPPGPSG 587
           GE G PGP G  GLPG                 G PGP GPPGP GP+G
Sbjct: 246 GENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAG 294



 Score =  149 bits (377), Expect = 7e-36
 Identities = 80/176 (45%), Positives = 94/176 (53%), Gaps = 10/176 (5%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
           +GP G +GPRG+ G+ G PGP G  G  G  G PG  G AG  G  G  G PG RG  G 
Sbjct: 314 RGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGP 373

Query: 502 KGSQGPKGSRGSPGKP------GPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGE 555
           +G+ GP G +G  G+P      G QGP G+PGP GP G  G  G +G  G +G  G VG 
Sbjct: 374 QGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGP 433

Query: 556 PGVPGPRGLP---GLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
            G PG RG P   G PG  G+ GPKG PG  GPSG   P     +P   P + G P
Sbjct: 434 IGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDP-GRPGEPGLP 488



 Score =  148 bits (373), Expect = 2e-35
 Identities = 79/169 (46%), Positives = 96/169 (56%), Gaps = 16/169 (9%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           G PGPRGP G +G+ GP GP      KG+ GEPG  G  GE+GP G  GP G +G  G  
Sbjct: 363 GFPGPRGPPGPQGATGPLGP------KGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA 416

Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGP---PGKEGLPGPQGPPGFQGLQGTVGEPGVP 559
           G +G +G+RG PG  GP GP G+ G PG    PG++GL GP+G PG +G  G  G  G  
Sbjct: 417 GEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGAN 476

Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
           G  G PG PG+PG  G  G PG  GP G V        P+ AP ++G P
Sbjct: 477 GDPGRPGEPGLPGARGLTGRPGDAGPQGKV-------GPSGAPGEDGRP 518



 Score =  147 bits (371), Expect = 3e-35
 Identities = 77/172 (44%), Positives = 92/172 (53%), Gaps = 7/172 (4%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           GP G  GP G  G+QGPPG  G  G++G  G  GP G  G+ G  GP G PG+ GG+G  
Sbjct: 660 GPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLT 719

Query: 503 GS---QGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559
           G     GP G+ G  G+ GP GP+G  G  G PG+ G  GP GP GF G  G  G+PG  
Sbjct: 720 GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAK 779

Query: 560 GPRGLPGLPGVPGMPGPKGP---PGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
           G +G  G  G  G PGP+GP   PGP GP+G   P   +    P P   G P
Sbjct: 780 GEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP-PGATGFP 830



 Score =  146 bits (369), Expect = 6e-35
 Identities = 79/175 (45%), Positives = 91/175 (52%), Gaps = 8/175 (4%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
            QG PG  G RG  G  GPPG TG  G+ G +G PG  GP G  G  G  G  GE G  G+
Sbjct: 938  QGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGA 997

Query: 502  KGSQGPKGSRGSPGKPGPQGPSGDPG------PPGPPGKEGLPGPQGPPGFQGLQGTVGE 555
             G+ GP GS G  G  G QG  G+ G      P GP G  G+ GPQGP G +G  G  GE
Sbjct: 998  PGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGE 1057

Query: 556  PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPED--NGCP 608
             G+ G RG  GL G+PG PGP G  G  GP+G   P        P+ +D  NG P
Sbjct: 1058 RGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIP 1112



 Score =  146 bits (368), Expect = 8e-35
 Identities = 78/162 (48%), Positives = 86/162 (53%), Gaps = 9/162 (5%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           G PG RG  G  G  GP G  G  G  GE G PGPPGP G RG  G  G PG +G  G  
Sbjct: 486 GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEP 545

Query: 503 GSQGPKGS------RGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
           G  G KG       RG PGK G  G +G PGP GP G+ G  G  GP GFQGL G  G P
Sbjct: 546 GKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPP 605

Query: 557 GV---PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQ 595
           G    PG +G+PG  G PG+ GP+G  G PG  G+     LQ
Sbjct: 606 GEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQ 647



 Score =  145 bits (365), Expect = 2e-34
 Identities = 73/148 (49%), Positives = 86/148 (58%), Gaps = 3/148 (2%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           G PG  GPRG+RG  G  G  G +G +G +G PG PG  G +G  GPAGPPG +G  G +
Sbjct: 621 GAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQ 680

Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKE---GLPGPQGPPGFQGLQGTVGEPGVP 559
           G  G +G+ G  G  G +G  G+ GP G PGK+   GL GP GPPG  G  G  GE G P
Sbjct: 681 GMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPP 740

Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           GP G  G  G PG  G  GPPGP G +G
Sbjct: 741 GPAGSAGARGAPGERGETGPPGPAGFAG 768



 Score =  144 bits (363), Expect = 3e-34
 Identities = 74/151 (49%), Positives = 85/151 (56%), Gaps = 6/151 (3%)

Query: 443 GPPGPRGPRGDRGSQGPPG------PTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGER 496
           GPPGP GP G  G  G PG      PTG +G +G +G  G PG  G  GP G +G PG  
Sbjct: 285 GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTD 344

Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
           G  G+KGS G  G  G+PG PGP+GP G  G  GP G +G  G  G  GF+G QG  GEP
Sbjct: 345 GIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 404

Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           G  GP+G PG  G  G  G +G PG  GP G
Sbjct: 405 GPAGPQGAPGPAGEEGKRGARGEPGGVGPIG 435



 Score =  144 bits (362), Expect = 4e-34
 Identities = 80/175 (45%), Positives = 86/175 (49%), Gaps = 46/175 (26%)

Query: 460 PGPTGNKGQKGE-KGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPG 518
           PGP G KG+ G+ K   GP GP G +GP G  GP G+RG KG KG+ GP+G  G PG PG
Sbjct: 31  PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPG 90

Query: 519 PQGPSGDPGPPGPPG---------------------------------KEGLPGPQGPPG 545
             GP G PGPPGPPG                                   G PGP G PG
Sbjct: 91  NPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPG 150

Query: 546 FQGLQGTVGEPGVP------GPRGLPGLPGVP------GMPGPKGPPGPPGPSGA 588
            QG QG  GEPG P      GPRG PG PG P      G PG  G  GPPGP GA
Sbjct: 151 PQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGA 205



 Score =  143 bits (361), Expect = 5e-34
 Identities = 81/174 (46%), Positives = 89/174 (51%), Gaps = 24/174 (13%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG--- 498
           +G PG RG  G +G QGP G  G  G  G KG  GP GP G +GP G  G PGERG    
Sbjct: 632 RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 691

Query: 499 ---KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL------PGPQGPPGFQGL 549
              KG +G  G KG  G+PGK G +G +G  GPPGP G  G       PGP G  G +G 
Sbjct: 692 AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA 751

Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPK------------GPPGPPGPSGAVVP 591
            G  GE G PGP G  G PG  G PG K            G PGP GPSGA  P
Sbjct: 752 PGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGP 805



 Score =  137 bits (345), Expect = 4e-32
 Identities = 69/145 (47%), Positives = 81/145 (55%), Gaps = 6/145 (4%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            GPPG +G  GD G  G  GP G +G  G++G  G PG  GERG  G  GP GE G +G+ 
Sbjct: 882  GPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAP 941

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
            G+ G +G  G  G PG  GP+G+      PG+EG PG  GPPG  G  G  G+ G  G  
Sbjct: 942  GASGDRGPPGPVGPPGLTGPAGE------PGREGSPGADGPPGRDGAAGVKGDRGETGAV 995

Query: 563  GLPGLPGVPGMPGPKGPPGPPGPSG 587
            G PG PG PG PGP GP G  G  G
Sbjct: 996  GAPGAPGPPGSPGPAGPTGKQGDRG 1020



 Score =  125 bits (314), Expect = 1e-28
 Identities = 66/151 (43%), Positives = 75/151 (49%), Gaps = 37/151 (24%)

Query: 474 EPGPPGPAGE----------------RGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKP 517
           +PGP G  GE                +GP G  GP G+RG KG KG+ GP+G  G PG P
Sbjct: 30  QPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTP 89

Query: 518 GPQGPSGDPGPPGPPGKEG---------------------LPGPQGPPGFQGLQGTVGEP 556
           G  GP G PGPPGPPG  G                     + GP GP G +G  G  G P
Sbjct: 90  GNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAP 149

Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           G  G +G PG PG PG+ GP GP GPPGP G
Sbjct: 150 GPQGFQGNPGEPGEPGVSGPMGPRGPPGPPG 180



 Score = 97.1 bits (240), Expect = 5e-20
 Identities = 47/90 (52%), Positives = 53/90 (58%), Gaps = 3/90 (3%)

Query: 436  KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGE 495
            + FT LQG PGP GP GD+G+ GP GP+   G +G  G  GP G  G  G  GP GPPG 
Sbjct: 1064 RGFTGLQGLPGPPGPSGDQGASGPAGPS---GPRGPPGPVGPSGKDGANGIPGPIGPPGP 1120

Query: 496  RGGKGSKGSQGPKGSRGSPGKPGPQGPSGD 525
            RG  G  G  GP G+ G PG PGP GP  D
Sbjct: 1121 RGRSGETGPAGPPGNPGPPGPPGPPGPGID 1150



 Score = 37.4 bits (85), Expect = 0.051
 Identities = 21/56 (37%), Positives = 26/56 (46%), Gaps = 4/56 (7%)

Query: 553 VGEPGVPGPRGLPG----LPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPED 604
           V +PG  G +G PG    + G  G PGP+GP G  GP G       +  P P   D
Sbjct: 28  VRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRD 83


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
           sapiens]
          Length = 1424

 Score =  166 bits (421), Expect = 6e-41
 Identities = 87/173 (50%), Positives = 104/173 (60%), Gaps = 16/173 (9%)

Query: 441 LQGPPGPRGPRGDRGS---QGPPGPTGN---KGQKGEKGEPGPPGPAGERGPIGPAGPPG 494
           L+G PG +G  G  G+   +G PGP G     G+KG++G PG PG  G  GP GPAGPPG
Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617

Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD-------PGPPGPPGKEGLPGPQGPPGFQ 547
             G +G  G QG +G  G+PG PG  GP G+       PGPPGPPG  G PGPQGPPG  
Sbjct: 618 Y-GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIP 676

Query: 548 GLQGTVGEPGVPGPRGLPGLPGV--PGMPGPKGPPGPPGPSGAVVPLALQNEP 598
           G  G  G+PG+PGP G PG+PG+  PG PGPKG  G PG  G++       EP
Sbjct: 677 GSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEP 729



 Score =  149 bits (376), Expect = 9e-36
 Identities = 87/209 (41%), Positives = 98/209 (46%), Gaps = 42/209 (20%)

Query: 435  IKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG------ 488
            +K    L GP GP GPRGD GS G PG  G +G  G  G  G PG  G+RG +G      
Sbjct: 980  LKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAG 1039

Query: 489  -----------------------PAGPPGERGGKGSKGSQGPKGSRGSPGKPG---PQGP 522
                                     GPPG  G  G  G  G KG  G PG PG   P GP
Sbjct: 1040 RPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGP 1099

Query: 523  SGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGP------ 576
             G PG PG PG  G PGP G  GF+G++G +G PG+ GP   PGLPG PG PGP      
Sbjct: 1100 EGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGP---PGLPGFPGSPGPMGIRGD 1156

Query: 577  KGPPGPPGPSGAVVPLALQNEPTPAPEDN 605
            +G  G PGP+G      L   P P P  N
Sbjct: 1157 QGRDGIPGPAGEKGETGLLRAP-PGPRGN 1184



 Score =  145 bits (367), Expect = 1e-34
 Identities = 98/222 (44%), Positives = 109/222 (49%), Gaps = 52/222 (23%)

Query: 440  ILQGPPGPRG------PRGDRGSQGPPGPTGNKGQKGEKGEPGP------PGPAGERGPI 487
            +L+ PPGPRG       +GDRG+ G PG  G KG  G+ G  GP      PGP G  G I
Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233

Query: 488  GPA-----GPPGERGGKGSKGSQGP--------KGSRGSPGKPGPQGP---SGDPGPPG- 530
             P      GPPG RG  G+ G  GP        KG +GS G PGP+GP   +GD GPPG 
Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293

Query: 531  --PPGKEGLPGPQGPPGFQGLQGTVGEPG---------VPGPRGLPGLPGVPGMPGP--- 576
               PG  GLPGP+G PGFQG  G  GE G          PGP G  G PGV G PG    
Sbjct: 1294 LGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKI 1353

Query: 577  ---KGPPGPPGPSGAVVPLALQNEP-TPAPEDN--GCPPHWK 612
                G PGPPG  G      +Q EP  P P  N   C P  K
Sbjct: 1354 ISLPGSPGPPGTPGEP---GMQGEPGPPGPPGNLGPCGPRGK 1392



 Score =  145 bits (367), Expect = 1e-34
 Identities = 85/187 (45%), Positives = 93/187 (49%), Gaps = 20/187 (10%)

Query: 432  GQLIKNFTILQGPPGPRGPRGDRGSQGPPGP--TGNKGQKGEKGEPGPPGPAGERGPIGP 489
            G +I   T  +GPPG RG  G  G  GPPG    G KG KG  G PGP GP G  G +GP
Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP 1290

Query: 490  AGP---------PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG---- 536
             G          PG RG  G +G  G KG +G+PG  G  GP G  GP GPPG  G    
Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGT 1350

Query: 537  -----LPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
                 LPG  GPPG  G  G  GEPG PGP G  G  G  G PG  G PG PGP+G    
Sbjct: 1351 LKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGN 1410

Query: 592  LALQNEP 598
               + EP
Sbjct: 1411 KGSKGEP 1417



 Score =  144 bits (363), Expect = 3e-34
 Identities = 81/158 (51%), Positives = 91/158 (57%), Gaps = 9/158 (5%)

Query: 439 TILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498
           T + GPPGP GP G  G QGPPG  G+ G+ G+ G PGP G  G  G IG  GPPG    
Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG-IGFPGPPGP--- 707

Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG--LPGPQGPPGFQGLQGTVGEP 556
           KG +G  G KGS G PGK G  G  G PG PG  G+    +PG  G PGF G +G  GE 
Sbjct: 708 KGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767

Query: 557 GVPGPRGLPGLPGVPG---MPGPKGPPGPPGPSGAVVP 591
           G  G  GLPGLPG PG   + GP+G PG PGP G   P
Sbjct: 768 GEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGP 805



 Score =  143 bits (361), Expect = 5e-34
 Identities = 81/195 (41%), Positives = 94/195 (48%), Gaps = 35/195 (17%)

Query: 443  GPPGPRGPRGDRGSQGPPG--------PTGNKGQKGEKGEPGPPGPAGERGP--IGPAGP 492
            G  GPRGP G  G  GPPG         TGN+G  G +G PG PGP G  G   IG  G 
Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGD 1269

Query: 493  PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552
             G  G  G KG  G  G  G PG+ G  G  G PGP G PG +G PG +G  G  G  G+
Sbjct: 1270 KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS 1329

Query: 553  VGEPGVPGPRGLPGL------------------PGVPGMPGPKGPPGPPGPSGAVVPLAL 594
            +G PG  GP+G PG+                  PG PG PG +G PGPPGP G + P   
Sbjct: 1330 IGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGP 1389

Query: 595  QNEP-------TPAP 602
            + +P       TP P
Sbjct: 1390 RGKPGKDGKPGTPGP 1404



 Score =  141 bits (355), Expect = 2e-33
 Identities = 80/171 (46%), Positives = 92/171 (53%), Gaps = 26/171 (15%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQ------KGEKGEPGPPGPA---------GERGPI 487
            GPPGP G  G  G +G PG  G KGQ      KGE+G+ G PGP+         GE G  
Sbjct: 901  GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLK 960

Query: 488  GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD---PGPPGPPGKEGLPGPQGPP 544
            G AG PGE+G +G  G  G KG +G PG  GP GP GD    G PG PG  G+PG  G  
Sbjct: 961  GFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNM 1020

Query: 545  GFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGP--------PGPPGPSG 587
            G  G +G  G  G PG  G PGLPG+ G+ G KG         PGPPGP+G
Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071



 Score =  139 bits (351), Expect = 7e-33
 Identities = 82/187 (43%), Positives = 93/187 (49%), Gaps = 24/187 (12%)

Query: 442  QGPPGPRGPRGDRGSQGP---------------PGPTGNKGQKGEKGEPGPPGPAGERGP 486
            +G PG +G +GD+G+ GP                G  GN G+KG +G PG PG  G +G 
Sbjct: 927  RGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGL 986

Query: 487  IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF 546
             GPAGPPG RG  GS G+ G  G RG PG  G  G  G  G  G  G  G  G  G PG 
Sbjct: 987  PGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGI 1046

Query: 547  QGLQGTVGEPGV-----PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601
             GLQG  GEPG      PGP G  G PG+PG  G KG  G PGP G + P      P  A
Sbjct: 1047 HGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAG----PEGA 1102

Query: 602  PEDNGCP 608
            P   G P
Sbjct: 1103 PGSPGSP 1109



 Score =  139 bits (350), Expect = 9e-33
 Identities = 82/177 (46%), Positives = 94/177 (53%), Gaps = 21/177 (11%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG------PIGPAGP--PG 494
           G PGP GP+GD+G  G  G  G  G+ GE G PG PG  G +G      P GP  P  PG
Sbjct: 700 GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 495 ERGGKGSKGSQGPKGSRGSPGKPG------PQGPSGDPGPP---GPPGK--EGLPGPQGP 543
           ERG  G  G  G  G  G PG PG      P+G  G PGPP   GPPG+  EG  G QG 
Sbjct: 760 ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819

Query: 544 PGFQGLQGTVGEPGVPGPRGLPGLPGV--PGMPGPKGPPGPPGPSGAVVPLALQNEP 598
           PG  GL+G  G  G  GP+G PG+PG+   G PG  G PG PG  G + PL  +  P
Sbjct: 820 PGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876



 Score =  139 bits (349), Expect = 1e-32
 Identities = 78/174 (44%), Positives = 94/174 (54%), Gaps = 13/174 (7%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
           +G PG  G +G  G  G PG  G++G KG +G PG  G  G +G  G  GPPG RG    
Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEY 346

Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP-----QGPPGFQGLQGTVGEP 556
             +   KG  G+PG PGP+G  G  GP GPPG  G PG      +G PG+ GL+G+ GE 
Sbjct: 347 YDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGER 406

Query: 557 GVPG--PRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
           G PG    G PG PG  G PG  G PGPPGP G +V    +  P   P D+G P
Sbjct: 407 GRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIV---FRKGP---PGDHGLP 454



 Score =  138 bits (347), Expect = 2e-32
 Identities = 93/232 (40%), Positives = 109/232 (46%), Gaps = 68/232 (29%)

Query: 441 LQGPPGP---------RGPRGDRGSQGPPGPTGNKGQ---------------------KG 470
           LQG PG           G +G+RG  G  G  G KGQ                     KG
Sbjct: 295 LQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG 354

Query: 471 EKGEPGPPGPAGERGPIGPAGPPGERGGKGSK-----------GSQGPKGSRGSPGK--- 516
           ++G PGPPGP G RGP GP+GPPG  G  GS            G +G KG RG PGK   
Sbjct: 355 DEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAM 414

Query: 517 --PGPQGPSGDPGPPGPPGKEGLPGP----QGPPGFQGLQGTVGEPGVP---GPRGLPGL 567
             PG  G +G PG PG PG  G PG     +GPPG  GL G +G PG+P   GP+G PGL
Sbjct: 415 GTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGL 474

Query: 568 -----------PGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
                      PG+PG+PG  G  G PG  GA     L+  P  +P + G P
Sbjct: 475 LCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA---GLKGSP-GSPGNTGLP 522



 Score =  137 bits (345), Expect = 4e-32
 Identities = 73/154 (47%), Positives = 86/154 (55%), Gaps = 9/154 (5%)

Query: 443  GPPGPRGP---RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499
            GPPG  G     G  G+ GPPGP GN G  G++G PG PG  G+RG  G  G  G++G  
Sbjct: 883  GPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNP 942

Query: 500  GSK------GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553
            G        G +G  G +G  G PG +G  G PG PG  G +GLPGP GPPG +G  G+ 
Sbjct: 943  GPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGST 1002

Query: 554  GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
            G PG PG RG+PG  G  GMPG KG  G  G  G
Sbjct: 1003 GNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036



 Score =  135 bits (341), Expect = 1e-31
 Identities = 78/180 (43%), Positives = 90/180 (50%), Gaps = 23/180 (12%)

Query: 442  QGPPGPRGPRGD--------------RGSQGPPGPTGNKGQKGEKGEPGPPG---PAGER 484
            QG  G  GP+GD               GS G PG  G  G  G++G PG PG   P GE 
Sbjct: 829  QGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGED 888

Query: 485  GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQ--- 541
            G IG  G PG  G  G  G+ G  G RGSPG PG +G  G PG  G  G +G PGP    
Sbjct: 889  GVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEIS 948

Query: 542  ---GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598
               G  G  GL+G  G PG  G RG+PG+PG+ G+ G  GP GPPGP G +       EP
Sbjct: 949  HVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEP 1008



 Score =  135 bits (341), Expect = 1e-31
 Identities = 91/228 (39%), Positives = 105/228 (46%), Gaps = 48/228 (21%)

Query: 421  MEEMKLVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQ-----------GPPGPTGN---K 466
            M  M +  SK  +    F    G PG  G  G +G +           GPPGPTG+    
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 467  GQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGP------KGSRGSPGKPGPQ 520
            G  G+KGE G PGP G  GP GP G PG  G  G  G  GP      KG +G  G PG +
Sbjct: 1077 GDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIR 1136

Query: 521  GPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV----PGPRGLP---------GL 567
            GP G PG PG PG  G+ G QG  G  G  G  GE G+    PGPRG P         G 
Sbjct: 1137 GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGA 1196

Query: 568  PGVPGMP---------GPKGP------PGPPGPSGAVVPLALQNEPTP 600
            PG PG+P         GP+GP      PGPPG  GA++P    N   P
Sbjct: 1197 PGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPP 1244



 Score =  133 bits (335), Expect = 5e-31
 Identities = 84/215 (39%), Positives = 103/215 (47%), Gaps = 53/215 (24%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG- 500
            +G PG +G  G+ G +G  G  G  G KG KG PGP GP G RG +G  G PGE G +G 
Sbjct: 954  KGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGI 1013

Query: 501  -----------SKGSQGP------------------KGSRGSPG-----KPGPQGPSGDP 526
                       SKG +G                   +G +G PG     +PGP GP+GDP
Sbjct: 1014 PGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDP 1073

Query: 527  GPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLP------------GVPGMP 574
            G PG  GK+G  G  GPPG  G  G  G PG PG  GLPG P            G+ G P
Sbjct: 1074 GLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPP 1133

Query: 575  GPKGPPGPPGPSGAVVPLALQNE------PTPAPE 603
            G +GPPG PG  G+  P+ ++ +      P PA E
Sbjct: 1134 GIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE 1168



 Score =  132 bits (332), Expect = 1e-30
 Identities = 69/159 (43%), Positives = 81/159 (50%), Gaps = 20/159 (12%)

Query: 446 GPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQ 505
           G +G +G++G  GPPG  G KG  G +G PGP GP G  G  G  G  G RG  G  G  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 506 GPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV------------ 553
           G  G  G+PG  GP G  G PG  G  G++G PG  G  G+ G+ G              
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 554 --------GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPG 584
                   G+PG+PG  G  GLPG PG PGP GPPGPPG
Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPG 201



 Score =  129 bits (325), Expect = 8e-30
 Identities = 72/154 (46%), Positives = 82/154 (53%), Gaps = 26/154 (16%)

Query: 464 GNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPS 523
           G KG+KGEKG PGPPG  G++G  GP G PG +G KG  G  G  GS+G  G  G  G S
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 524 GDPGPPGPPGKEG---------LPGPQGPPGFQGLQGTVGEPGVPGPRGLPGL------- 567
           G PG PG PG  G           G +G  GF GL GT+G PG+PG  GL G        
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 568 ----------PGVPGMPGPKGPPGPPGPSGAVVP 591
                     PG+PG PGP+G PGPPG  G V P
Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP 196



 Score =  129 bits (324), Expect = 1e-29
 Identities = 82/194 (42%), Positives = 90/194 (46%), Gaps = 31/194 (15%)

Query: 441 LQGPPGPRGPRGDRG-SQGPPGPTGNKGQKGEKGEPGPPGPAGERG-----------PIG 488
           L G PGP GP GD    +GPPG  G  G  G  G PG  GP GE G           P G
Sbjct: 428 LPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPG 487

Query: 489 PAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPG-------PQ 541
             G PG  G KG  G QG  G +GSPG PG  G  G PG PG  G  GL G       P+
Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPE 547

Query: 542 GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKG------------PPGPPGPSGAV 589
           G  G  G  G  G+PG  G  G+PG PGV G+PGPKG            PPG PG  G+ 
Sbjct: 548 GQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSP 607

Query: 590 VPLALQNEPTPAPE 603
            P      P   P+
Sbjct: 608 GPAGPAGPPGYGPQ 621



 Score =  125 bits (315), Expect = 1e-28
 Identities = 79/186 (42%), Positives = 88/186 (47%), Gaps = 34/186 (18%)

Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQK------GEKGEPGPPGPAGERGPIGP 489
           K FT  +G PGP+GP   +G  G PG TG+KG +      G  G PG PG  G  GP G 
Sbjct: 63  KGFTGPEGLPGPQGP---KGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGL 119

Query: 490 AGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPP-----------GPPGKEGLP 538
            G PG  G KG +G  G  G+ G PG PG  G  G  G P           G PG  G P
Sbjct: 120 VGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAP 179

Query: 539 GPQGPPGFQGLQGTVGEPGVPGPRGLPG--------------LPGVPGMPGPKGPPGPPG 584
           GPQG PG  G  G VG PG PG  G PG              + G  G  G KG  GPPG
Sbjct: 180 GPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPG 239

Query: 585 PSGAVV 590
           P G V+
Sbjct: 240 PPGTVI 245



 Score =  124 bits (312), Expect = 2e-28
 Identities = 75/184 (40%), Positives = 89/184 (48%), Gaps = 39/184 (21%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGN--------KGQKGEKGEPGPPGPAGE-----RGPIGP 489
           GPPGP G  G  G+ GP GP G+        KG++G KG  GPPGP G       GP   
Sbjct: 195 GPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNR 254

Query: 490 AGPPGERGGKGSKGSQGPKG-----------SRGSPGKPGPQGPSGDPGPPGPPGKEGL- 537
               GE+G KG+ G  GP G            +G+PG PG QG  G  G PG PG EG+ 
Sbjct: 255 TDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVK 314

Query: 538 -----PGPQGPPGFQGLQGTVGEPGVPGP---------RGLPGLPGVPGMPGPKGPPGPP 583
                PG  G  G +G +G +G PG  GP         +G  G PG PG  G +GP GP 
Sbjct: 315 GNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPS 374

Query: 584 GPSG 587
           GP G
Sbjct: 375 GPPG 378



 Score =  124 bits (311), Expect = 3e-28
 Identities = 77/176 (43%), Positives = 85/176 (48%), Gaps = 36/176 (20%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP-------IGPAGPP 493
           ++G PG +G  G +GS G PG TG  G  G  G  G PG  GE+G        +G  G P
Sbjct: 497 VKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDP 556

Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGPQGP------SGDPGPPGPPGKEGLPGPQGPPGFQ 547
           G RG  G KG  G  G+ G  G PGP+G        GD GPPG PG  G PGP GP G  
Sbjct: 557 GLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPP 616

Query: 548 GLQGTVGEPGVPGPRGLPGLPGVPGMPGP----------------KGPPGPPGPSG 587
           G  G  GEPG      L G  GVPG PGP                 GPPGPPGP G
Sbjct: 617 GY-GPQGEPG------LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665



 Score =  124 bits (310), Expect = 4e-28
 Identities = 89/233 (38%), Positives = 99/233 (42%), Gaps = 67/233 (28%)

Query: 443 GPPGP-------RGPRGDRGSQGPPGPTGNKGQKGEKGEPG-----------PPGPAGER 484
           GPPGP       +GP GD G  G  G  G  G  G KGEPG           PPG  G  
Sbjct: 433 GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLP 492

Query: 485 GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPG----------PPGPPGK 534
           G  G  G PG +G  G KGS G  G+ G PG PG  G  GDPG          P G  G 
Sbjct: 493 GLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGV 552

Query: 535 EGLPGPQGPPGFQGLQGTVGEPGV---PGPRGL------------PGLPGVPGMPGPKGP 579
            G PG +G PG +GL G  G PGV   PGP+G             PG PG PG PGP GP
Sbjct: 553 PGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGP 612

Query: 580 -----------------------PGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609
                                  PGPPG +G    L++ + P P P     PP
Sbjct: 613 AGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSV-STPVPGPPGPPGPP 664



 Score =  122 bits (306), Expect = 1e-27
 Identities = 77/179 (43%), Positives = 90/179 (50%), Gaps = 34/179 (18%)

Query: 443 GPPGPRGPRGDRGS------QGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPA------ 490
           G PG RG  G+ G        G PG  GN+G  G +G+PG PGP GE+GP G        
Sbjct: 756 GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815

Query: 491 --GPPGERGGKGSKGSQGPKGSRGSPGKPGPQ-----GPSGDPGPPG------PPGKEGL 537
             G PG  G KG +G +G  G +G PG PG       G +G PG PG      P G+ G 
Sbjct: 816 AQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGY 875

Query: 538 PGPQG---PPGFQGLQGTVGEPGV---PGPRGLPGLP---GVPGMPGPKGPPGPPGPSG 587
           PG  G   PPG  G+ G +G PG    PGP G PG P   G PG+PG KG  G PG  G
Sbjct: 876 PGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKG 934



 Score =  117 bits (292), Expect = 5e-26
 Identities = 74/173 (42%), Positives = 82/173 (47%), Gaps = 36/173 (20%)

Query: 451 RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGE---RGPIGPAGPPGERGGK--GSKGSQ 505
           +GD G  G PGP G  G  G  G  GPPGP G     G +GP GP G  G +  G KG +
Sbjct: 170 KGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGER 229

Query: 506 GPKGSRGSPGKPGP-----------------QGPSGDPGPPGPPGKEGLPGP-----QGP 543
           G KG  G PG PG                  +G  G  G PGPPG  GLPG      +G 
Sbjct: 230 GVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGA 289

Query: 544 PGFQGLQGTVGEPGVP---------GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           PG  GLQG  G+ GVP         G RG PGL G  G+ G KG  GPPG  G
Sbjct: 290 PGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRG 342



 Score =  115 bits (289), Expect = 1e-25
 Identities = 80/211 (37%), Positives = 91/211 (43%), Gaps = 32/211 (15%)

Query: 426 LVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG 485
           L  SK  + I       G PG  G  G+ G  G  G  G  G KGE+G PG PG  G  G
Sbjct: 86  LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145

Query: 486 PIGPAGPPGERGGKG--------SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL 537
             G AG  G++G           +KG  G  G+ G  G PGP G  G  GPPGPPG  G 
Sbjct: 146 IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205

Query: 538 PGPQGPPGFQGLQG--TVGEPGVPGPRGLPGLPGVPGM--------------------PG 575
           PG  GP G +G  G   +G  G  G +GL G PG PG                      G
Sbjct: 206 PGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKG 265

Query: 576 PKGPPGPPGPSGAVVPLALQNEPTPAPEDNG 606
             G PGPPGPSG  +P         AP D G
Sbjct: 266 AMGEPGPPGPSG--LPGESYGSEKGAPGDPG 294


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
           sapiens]
          Length = 1494

 Score =  166 bits (421), Expect = 6e-41
 Identities = 87/173 (50%), Positives = 104/173 (60%), Gaps = 16/173 (9%)

Query: 441 LQGPPGPRGPRGDRGS---QGPPGPTGN---KGQKGEKGEPGPPGPAGERGPIGPAGPPG 494
           L+G PG +G  G  G+   +G PGP G     G+KG++G PG PG  G  GP GPAGPPG
Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617

Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD-------PGPPGPPGKEGLPGPQGPPGFQ 547
             G +G  G QG +G  G+PG PG  GP G+       PGPPGPPG  G PGPQGPPG  
Sbjct: 618 Y-GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIP 676

Query: 548 GLQGTVGEPGVPGPRGLPGLPGV--PGMPGPKGPPGPPGPSGAVVPLALQNEP 598
           G  G  G+PG+PGP G PG+PG+  PG PGPKG  G PG  G++       EP
Sbjct: 677 GSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEP 729



 Score =  150 bits (380), Expect = 3e-36
 Identities = 88/193 (45%), Positives = 96/193 (49%), Gaps = 20/193 (10%)

Query: 432  GQLIKNFTILQGPPGPRGPRGDRGSQGPPGP--TGNKGQKGEKGEPGPPGPAGERGPIGP 489
            G +I   T  +GPPG RG  G  G  GPPG    G KG KG  G PGP GP G  G +GP
Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP 1290

Query: 490  AGP---------PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG---- 536
             G          PG RG  G +G  G KG +G+PG  G  GP G  GP GPPG  G    
Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGT 1350

Query: 537  -----LPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
                 LPG  GPPG  G  G  GEPG PGP G  G  G  G PG  G PG PGP+G    
Sbjct: 1351 LKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGN 1410

Query: 592  LALQNEPTPAPED 604
               + EP PA  D
Sbjct: 1411 KGSKGEPGPAGSD 1423



 Score =  149 bits (376), Expect = 9e-36
 Identities = 87/209 (41%), Positives = 98/209 (46%), Gaps = 42/209 (20%)

Query: 435  IKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG------ 488
            +K    L GP GP GPRGD GS G PG  G +G  G  G  G PG  G+RG +G      
Sbjct: 980  LKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAG 1039

Query: 489  -----------------------PAGPPGERGGKGSKGSQGPKGSRGSPGKPG---PQGP 522
                                     GPPG  G  G  G  G KG  G PG PG   P GP
Sbjct: 1040 RPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGP 1099

Query: 523  SGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGP------ 576
             G PG PG PG  G PGP G  GF+G++G +G PG+ GP   PGLPG PG PGP      
Sbjct: 1100 EGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGP---PGLPGFPGSPGPMGIRGD 1156

Query: 577  KGPPGPPGPSGAVVPLALQNEPTPAPEDN 605
            +G  G PGP+G      L   P P P  N
Sbjct: 1157 QGRDGIPGPAGEKGETGLLRAP-PGPRGN 1184



 Score =  145 bits (367), Expect = 1e-34
 Identities = 98/222 (44%), Positives = 109/222 (49%), Gaps = 52/222 (23%)

Query: 440  ILQGPPGPRG------PRGDRGSQGPPGPTGNKGQKGEKGEPGP------PGPAGERGPI 487
            +L+ PPGPRG       +GDRG+ G PG  G KG  G+ G  GP      PGP G  G I
Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233

Query: 488  GPA-----GPPGERGGKGSKGSQGP--------KGSRGSPGKPGPQGP---SGDPGPPG- 530
             P      GPPG RG  G+ G  GP        KG +GS G PGP+GP   +GD GPPG 
Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293

Query: 531  --PPGKEGLPGPQGPPGFQGLQGTVGEPG---------VPGPRGLPGLPGVPGMPGP--- 576
               PG  GLPGP+G PGFQG  G  GE G          PGP G  G PGV G PG    
Sbjct: 1294 LGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKI 1353

Query: 577  ---KGPPGPPGPSGAVVPLALQNEP-TPAPEDN--GCPPHWK 612
                G PGPPG  G      +Q EP  P P  N   C P  K
Sbjct: 1354 ISLPGSPGPPGTPGEP---GMQGEPGPPGPPGNLGPCGPRGK 1392



 Score =  144 bits (363), Expect = 3e-34
 Identities = 81/158 (51%), Positives = 91/158 (57%), Gaps = 9/158 (5%)

Query: 439 TILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498
           T + GPPGP GP G  G QGPPG  G+ G+ G+ G PGP G  G  G IG  GPPG    
Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG-IGFPGPPGP--- 707

Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG--LPGPQGPPGFQGLQGTVGEP 556
           KG +G  G KGS G PGK G  G  G PG PG  G+    +PG  G PGF G +G  GE 
Sbjct: 708 KGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767

Query: 557 GVPGPRGLPGLPGVPG---MPGPKGPPGPPGPSGAVVP 591
           G  G  GLPGLPG PG   + GP+G PG PGP G   P
Sbjct: 768 GEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGP 805



 Score =  141 bits (355), Expect = 2e-33
 Identities = 80/171 (46%), Positives = 92/171 (53%), Gaps = 26/171 (15%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQ------KGEKGEPGPPGPA---------GERGPI 487
            GPPGP G  G  G +G PG  G KGQ      KGE+G+ G PGP+         GE G  
Sbjct: 901  GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLK 960

Query: 488  GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD---PGPPGPPGKEGLPGPQGPP 544
            G AG PGE+G +G  G  G KG +G PG  GP GP GD    G PG PG  G+PG  G  
Sbjct: 961  GFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNM 1020

Query: 545  GFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGP--------PGPPGPSG 587
            G  G +G  G  G PG  G PGLPG+ G+ G KG         PGPPGP+G
Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071



 Score =  139 bits (351), Expect = 7e-33
 Identities = 82/187 (43%), Positives = 93/187 (49%), Gaps = 24/187 (12%)

Query: 442  QGPPGPRGPRGDRGSQGP---------------PGPTGNKGQKGEKGEPGPPGPAGERGP 486
            +G PG +G +GD+G+ GP                G  GN G+KG +G PG PG  G +G 
Sbjct: 927  RGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGL 986

Query: 487  IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF 546
             GPAGPPG RG  GS G+ G  G RG PG  G  G  G  G  G  G  G  G  G PG 
Sbjct: 987  PGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGI 1046

Query: 547  QGLQGTVGEPGV-----PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601
             GLQG  GEPG      PGP G  G PG+PG  G KG  G PGP G + P      P  A
Sbjct: 1047 HGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAG----PEGA 1102

Query: 602  PEDNGCP 608
            P   G P
Sbjct: 1103 PGSPGSP 1109



 Score =  139 bits (350), Expect = 9e-33
 Identities = 82/177 (46%), Positives = 94/177 (53%), Gaps = 21/177 (11%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG------PIGPAGP--PG 494
           G PGP GP+GD+G  G  G  G  G+ GE G PG PG  G +G      P GP  P  PG
Sbjct: 700 GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 495 ERGGKGSKGSQGPKGSRGSPGKPG------PQGPSGDPGPP---GPPGK--EGLPGPQGP 543
           ERG  G  G  G  G  G PG PG      P+G  G PGPP   GPPG+  EG  G QG 
Sbjct: 760 ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819

Query: 544 PGFQGLQGTVGEPGVPGPRGLPGLPGV--PGMPGPKGPPGPPGPSGAVVPLALQNEP 598
           PG  GL+G  G  G  GP+G PG+PG+   G PG  G PG PG  G + PL  +  P
Sbjct: 820 PGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876



 Score =  139 bits (349), Expect = 1e-32
 Identities = 78/174 (44%), Positives = 94/174 (54%), Gaps = 13/174 (7%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
           +G PG  G +G  G  G PG  G++G KG +G PG  G  G +G  G  GPPG RG    
Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEY 346

Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP-----QGPPGFQGLQGTVGEP 556
             +   KG  G+PG PGP+G  G  GP GPPG  G PG      +G PG+ GL+G+ GE 
Sbjct: 347 YDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGER 406

Query: 557 GVPG--PRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
           G PG    G PG PG  G PG  G PGPPGP G +V    +  P   P D+G P
Sbjct: 407 GRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIV---FRKGP---PGDHGLP 454



 Score =  138 bits (347), Expect = 2e-32
 Identities = 93/232 (40%), Positives = 109/232 (46%), Gaps = 68/232 (29%)

Query: 441 LQGPPGP---------RGPRGDRGSQGPPGPTGNKGQ---------------------KG 470
           LQG PG           G +G+RG  G  G  G KGQ                     KG
Sbjct: 295 LQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG 354

Query: 471 EKGEPGPPGPAGERGPIGPAGPPGERGGKGSK-----------GSQGPKGSRGSPGK--- 516
           ++G PGPPGP G RGP GP+GPPG  G  GS            G +G KG RG PGK   
Sbjct: 355 DEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAM 414

Query: 517 --PGPQGPSGDPGPPGPPGKEGLPGP----QGPPGFQGLQGTVGEPGVP---GPRGLPGL 567
             PG  G +G PG PG PG  G PG     +GPPG  GL G +G PG+P   GP+G PGL
Sbjct: 415 GTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGL 474

Query: 568 -----------PGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
                      PG+PG+PG  G  G PG  GA     L+  P  +P + G P
Sbjct: 475 LCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA---GLKGSP-GSPGNTGLP 522



 Score =  138 bits (347), Expect = 2e-32
 Identities = 76/163 (46%), Positives = 81/163 (49%), Gaps = 24/163 (14%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQ------------------KGEKGEPGPPGPAGER 484
            G PGP+GP G  G  GPPG  G  G                   KGEKG PG  G  G  
Sbjct: 1274 GHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPP 1333

Query: 485  GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPP 544
            GPIGP GPPG RG  G+       GS G PG PG  G  G+PGPPGPPG  G  GP+G P
Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393

Query: 545  GFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
            G        G+PG PGP G  G  G  G PGP G  G PG  G
Sbjct: 1394 GKD------GKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKG 1430



 Score =  137 bits (345), Expect = 4e-32
 Identities = 73/154 (47%), Positives = 86/154 (55%), Gaps = 9/154 (5%)

Query: 443  GPPGPRGP---RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499
            GPPG  G     G  G+ GPPGP GN G  G++G PG PG  G+RG  G  G  G++G  
Sbjct: 883  GPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNP 942

Query: 500  GSK------GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553
            G        G +G  G +G  G PG +G  G PG PG  G +GLPGP GPPG +G  G+ 
Sbjct: 943  GPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGST 1002

Query: 554  GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
            G PG PG RG+PG  G  GMPG KG  G  G  G
Sbjct: 1003 GNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036



 Score =  135 bits (341), Expect = 1e-31
 Identities = 78/180 (43%), Positives = 90/180 (50%), Gaps = 23/180 (12%)

Query: 442  QGPPGPRGPRGD--------------RGSQGPPGPTGNKGQKGEKGEPGPPG---PAGER 484
            QG  G  GP+GD               GS G PG  G  G  G++G PG PG   P GE 
Sbjct: 829  QGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGED 888

Query: 485  GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQ--- 541
            G IG  G PG  G  G  G+ G  G RGSPG PG +G  G PG  G  G +G PGP    
Sbjct: 889  GVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEIS 948

Query: 542  ---GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598
               G  G  GL+G  G PG  G RG+PG+PG+ G+ G  GP GPPGP G +       EP
Sbjct: 949  HVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEP 1008



 Score =  135 bits (341), Expect = 1e-31
 Identities = 91/228 (39%), Positives = 105/228 (46%), Gaps = 48/228 (21%)

Query: 421  MEEMKLVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQ-----------GPPGPTGN---K 466
            M  M +  SK  +    F    G PG  G  G +G +           GPPGPTG+    
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 467  GQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGP------KGSRGSPGKPGPQ 520
            G  G+KGE G PGP G  GP GP G PG  G  G  G  GP      KG +G  G PG +
Sbjct: 1077 GDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIR 1136

Query: 521  GPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV----PGPRGLP---------GL 567
            GP G PG PG PG  G+ G QG  G  G  G  GE G+    PGPRG P         G 
Sbjct: 1137 GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGA 1196

Query: 568  PGVPGMP---------GPKGP------PGPPGPSGAVVPLALQNEPTP 600
            PG PG+P         GP+GP      PGPPG  GA++P    N   P
Sbjct: 1197 PGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPP 1244



 Score =  135 bits (341), Expect = 1e-31
 Identities = 80/177 (45%), Positives = 89/177 (50%), Gaps = 6/177 (3%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            G PG  GPRGD G QG PG  G KG  G  G  GPPGP G +GP G  G PG        
Sbjct: 1298 GTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLP 1357

Query: 503  GSQGPKGSRGSP---GKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559
            GS GP G+ G P   G+PGP GP G+ GP GP GK G  G  G PG  G +G  G  G P
Sbjct: 1358 GSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEP 1417

Query: 560  GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA-PEDNGCPPHWKNFT 615
            GP G  GLPG+ G  G  G P      G V     Q    P+ PE  G  P +  F+
Sbjct: 1418 GPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPE--GTVPLYSGFS 1472



 Score =  133 bits (335), Expect = 5e-31
 Identities = 84/215 (39%), Positives = 103/215 (47%), Gaps = 53/215 (24%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG- 500
            +G PG +G  G+ G +G  G  G  G KG KG PGP GP G RG +G  G PGE G +G 
Sbjct: 954  KGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGI 1013

Query: 501  -----------SKGSQGP------------------KGSRGSPG-----KPGPQGPSGDP 526
                       SKG +G                   +G +G PG     +PGP GP+GDP
Sbjct: 1014 PGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDP 1073

Query: 527  GPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLP------------GVPGMP 574
            G PG  GK+G  G  GPPG  G  G  G PG PG  GLPG P            G+ G P
Sbjct: 1074 GLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPP 1133

Query: 575  GPKGPPGPPGPSGAVVPLALQNE------PTPAPE 603
            G +GPPG PG  G+  P+ ++ +      P PA E
Sbjct: 1134 GIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE 1168



 Score =  132 bits (332), Expect = 1e-30
 Identities = 69/159 (43%), Positives = 81/159 (50%), Gaps = 20/159 (12%)

Query: 446 GPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQ 505
           G +G +G++G  GPPG  G KG  G +G PGP GP G  G  G  G  G RG  G  G  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 506 GPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV------------ 553
           G  G  G+PG  GP G  G PG  G  G++G PG  G  G+ G+ G              
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 554 --------GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPG 584
                   G+PG+PG  G  GLPG PG PGP GPPGPPG
Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPG 201



 Score =  129 bits (325), Expect = 8e-30
 Identities = 72/154 (46%), Positives = 82/154 (53%), Gaps = 26/154 (16%)

Query: 464 GNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPS 523
           G KG+KGEKG PGPPG  G++G  GP G PG +G KG  G  G  GS+G  G  G  G S
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 524 GDPGPPGPPGK---------EGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGL------- 567
           G PG PG PG           G  G +G  GF GL GT+G PG+PG  GL G        
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 568 ----------PGVPGMPGPKGPPGPPGPSGAVVP 591
                     PG+PG PGP+G PGPPG  G V P
Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP 196



 Score =  129 bits (324), Expect = 1e-29
 Identities = 82/194 (42%), Positives = 90/194 (46%), Gaps = 31/194 (15%)

Query: 441 LQGPPGPRGPRGDRG-SQGPPGPTGNKGQKGEKGEPGPPGPAGERG-----------PIG 488
           L G PGP GP GD    +GPPG  G  G  G  G PG  GP GE G           P G
Sbjct: 428 LPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPG 487

Query: 489 PAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPG-------PQ 541
             G PG  G KG  G QG  G +GSPG PG  G  G PG PG  G  GL G       P+
Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPE 547

Query: 542 GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKG------------PPGPPGPSGAV 589
           G  G  G  G  G+PG  G  G+PG PGV G+PGPKG            PPG PG  G+ 
Sbjct: 548 GQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSP 607

Query: 590 VPLALQNEPTPAPE 603
            P      P   P+
Sbjct: 608 GPAGPAGPPGYGPQ 621



 Score =  125 bits (315), Expect = 1e-28
 Identities = 79/186 (42%), Positives = 88/186 (47%), Gaps = 34/186 (18%)

Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQK------GEKGEPGPPGPAGERGPIGP 489
           K FT  +G PGP+GP   +G  G PG TG+KG +      G  G PG PG  G  GP G 
Sbjct: 63  KGFTGPEGLPGPQGP---KGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGL 119

Query: 490 AGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPP-----------GPPGKEGLP 538
            G PG  G KG +G  G  G+ G PG PG  G  G  G P           G PG  G P
Sbjct: 120 VGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAP 179

Query: 539 GPQGPPGFQGLQGTVGEPGVPGPRGLPG--------------LPGVPGMPGPKGPPGPPG 584
           GPQG PG  G  G VG PG PG  G PG              + G  G  G KG  GPPG
Sbjct: 180 GPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPG 239

Query: 585 PSGAVV 590
           P G V+
Sbjct: 240 PPGTVI 245



 Score =  124 bits (312), Expect = 2e-28
 Identities = 75/184 (40%), Positives = 89/184 (48%), Gaps = 39/184 (21%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGN--------KGQKGEKGEPGPPGPAGE-----RGPIGP 489
           GPPGP G  G  G+ GP GP G+        KG++G KG  GPPGP G       GP   
Sbjct: 195 GPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNR 254

Query: 490 AGPPGERGGKGSKGSQGPKG-----------SRGSPGKPGPQGPSGDPGPPGPPGKEGL- 537
               GE+G KG+ G  GP G            +G+PG PG QG  G  G PG PG EG+ 
Sbjct: 255 TDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVK 314

Query: 538 -----PGPQGPPGFQGLQGTVGEPGVPGP---------RGLPGLPGVPGMPGPKGPPGPP 583
                PG  G  G +G +G +G PG  GP         +G  G PG PG  G +GP GP 
Sbjct: 315 GNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPS 374

Query: 584 GPSG 587
           GP G
Sbjct: 375 GPPG 378



 Score =  124 bits (311), Expect = 3e-28
 Identities = 77/176 (43%), Positives = 85/176 (48%), Gaps = 36/176 (20%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP-------IGPAGPP 493
           ++G PG +G  G +GS G PG TG  G  G  G  G PG  GE+G        +G  G P
Sbjct: 497 VKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDP 556

Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGPQGP------SGDPGPPGPPGKEGLPGPQGPPGFQ 547
           G RG  G KG  G  G+ G  G PGP+G        GD GPPG PG  G PGP GP G  
Sbjct: 557 GLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPP 616

Query: 548 GLQGTVGEPGVPGPRGLPGLPGVPGMPGP----------------KGPPGPPGPSG 587
           G  G  GEPG      L G  GVPG PGP                 GPPGPPGP G
Sbjct: 617 GY-GPQGEPG------LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665



 Score =  124 bits (310), Expect = 4e-28
 Identities = 89/233 (38%), Positives = 99/233 (42%), Gaps = 67/233 (28%)

Query: 443 GPPGP-------RGPRGDRGSQGPPGPTGNKGQKGEKGEPG-----------PPGPAGER 484
           GPPGP       +GP GD G  G  G  G  G  G KGEPG           PPG  G  
Sbjct: 433 GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLP 492

Query: 485 GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPG----------PPGPPGK 534
           G  G  G PG +G  G KGS G  G+ G PG PG  G  GDPG          P G  G 
Sbjct: 493 GLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGV 552

Query: 535 EGLPGPQGPPGFQGLQGTVGEPGV---PGPRGL------------PGLPGVPGMPGPKGP 579
            G PG +G PG +GL G  G PGV   PGP+G             PG PG PG PGP GP
Sbjct: 553 PGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGP 612

Query: 580 -----------------------PGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609
                                  PGPPG +G    L++ + P P P     PP
Sbjct: 613 AGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSV-STPVPGPPGPPGPP 664



 Score =  122 bits (306), Expect = 1e-27
 Identities = 77/179 (43%), Positives = 90/179 (50%), Gaps = 34/179 (18%)

Query: 443 GPPGPRGPRGDRGS------QGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPA------ 490
           G PG RG  G+ G        G PG  GN+G  G +G+PG PGP GE+GP G        
Sbjct: 756 GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815

Query: 491 --GPPGERGGKGSKGSQGPKGSRGSPGKPGPQ-----GPSGDPGPPG------PPGKEGL 537
             G PG  G KG +G +G  G +G PG PG       G +G PG PG      P G+ G 
Sbjct: 816 AQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGY 875

Query: 538 PGPQG---PPGFQGLQGTVGEPGV---PGPRGLPGLP---GVPGMPGPKGPPGPPGPSG 587
           PG  G   PPG  G+ G +G PG    PGP G PG P   G PG+PG KG  G PG  G
Sbjct: 876 PGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKG 934



 Score =  117 bits (292), Expect = 5e-26
 Identities = 74/173 (42%), Positives = 82/173 (47%), Gaps = 36/173 (20%)

Query: 451 RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGE---RGPIGPAGPPGERGGK--GSKGSQ 505
           +GD G  G PGP G  G  G  G  GPPGP G     G +GP GP G  G +  G KG +
Sbjct: 170 KGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGER 229

Query: 506 GPKGSRGSPGKPGP-----------------QGPSGDPGPPGPPGKEGLPGP-----QGP 543
           G KG  G PG PG                  +G  G  G PGPPG  GLPG      +G 
Sbjct: 230 GVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGA 289

Query: 544 PGFQGLQGTVGEPGVP---------GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           PG  GLQG  G+ GVP         G RG PGL G  G+ G KG  GPPG  G
Sbjct: 290 PGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRG 342



 Score =  115 bits (289), Expect = 1e-25
 Identities = 80/211 (37%), Positives = 91/211 (43%), Gaps = 32/211 (15%)

Query: 426 LVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG 485
           L  SK  + I       G PG  G  G+ G  G  G  G  G KGE+G PG PG  G  G
Sbjct: 86  LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145

Query: 486 PIGPAGPPGERGGKG--------SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL 537
             G AG  G++G           +KG  G  G+ G  G PGP G  G  GPPGPPG  G 
Sbjct: 146 IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205

Query: 538 PGPQGPPGFQGLQG--TVGEPGVPGPRGLPGLPGVPGM--------------------PG 575
           PG  GP G +G  G   +G  G  G +GL G PG PG                      G
Sbjct: 206 PGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKG 265

Query: 576 PKGPPGPPGPSGAVVPLALQNEPTPAPEDNG 606
             G PGPPGPSG  +P         AP D G
Sbjct: 266 AMGEPGPPGPSG--LPGESYGSEKGAPGDPG 294


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
           sapiens]
          Length = 1637

 Score =  166 bits (421), Expect = 6e-41
 Identities = 87/173 (50%), Positives = 104/173 (60%), Gaps = 16/173 (9%)

Query: 441 LQGPPGPRGPRGDRGS---QGPPGPTGN---KGQKGEKGEPGPPGPAGERGPIGPAGPPG 494
           L+G PG +G  G  G+   +G PGP G     G+KG++G PG PG  G  GP GPAGPPG
Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617

Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD-------PGPPGPPGKEGLPGPQGPPGFQ 547
             G +G  G QG +G  G+PG PG  GP G+       PGPPGPPG  G PGPQGPPG  
Sbjct: 618 Y-GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIP 676

Query: 548 GLQGTVGEPGVPGPRGLPGLPGV--PGMPGPKGPPGPPGPSGAVVPLALQNEP 598
           G  G  G+PG+PGP G PG+PG+  PG PGPKG  G PG  G++       EP
Sbjct: 677 GSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEP 729



 Score =  150 bits (380), Expect = 3e-36
 Identities = 88/193 (45%), Positives = 96/193 (49%), Gaps = 20/193 (10%)

Query: 432  GQLIKNFTILQGPPGPRGPRGDRGSQGPPGP--TGNKGQKGEKGEPGPPGPAGERGPIGP 489
            G +I   T  +GPPG RG  G  G  GPPG    G KG KG  G PGP GP G  G +GP
Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP 1290

Query: 490  AGP---------PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG---- 536
             G          PG RG  G +G  G KG +G+PG  G  GP G  GP GPPG  G    
Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGT 1350

Query: 537  -----LPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
                 LPG  GPPG  G  G  GEPG PGP G  G  G  G PG  G PG PGP+G    
Sbjct: 1351 LKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGN 1410

Query: 592  LALQNEPTPAPED 604
               + EP PA  D
Sbjct: 1411 KGSKGEPGPAGSD 1423



 Score =  149 bits (376), Expect = 9e-36
 Identities = 87/209 (41%), Positives = 98/209 (46%), Gaps = 42/209 (20%)

Query: 435  IKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG------ 488
            +K    L GP GP GPRGD GS G PG  G +G  G  G  G PG  G+RG +G      
Sbjct: 980  LKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAG 1039

Query: 489  -----------------------PAGPPGERGGKGSKGSQGPKGSRGSPGKPG---PQGP 522
                                     GPPG  G  G  G  G KG  G PG PG   P GP
Sbjct: 1040 RPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGP 1099

Query: 523  SGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGP------ 576
             G PG PG PG  G PGP G  GF+G++G +G PG+ GP   PGLPG PG PGP      
Sbjct: 1100 EGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGP---PGLPGFPGSPGPMGIRGD 1156

Query: 577  KGPPGPPGPSGAVVPLALQNEPTPAPEDN 605
            +G  G PGP+G      L   P P P  N
Sbjct: 1157 QGRDGIPGPAGEKGETGLLRAP-PGPRGN 1184



 Score =  145 bits (367), Expect = 1e-34
 Identities = 98/222 (44%), Positives = 109/222 (49%), Gaps = 52/222 (23%)

Query: 440  ILQGPPGPRG------PRGDRGSQGPPGPTGNKGQKGEKGEPGP------PGPAGERGPI 487
            +L+ PPGPRG       +GDRG+ G PG  G KG  G+ G  GP      PGP G  G I
Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233

Query: 488  GPA-----GPPGERGGKGSKGSQGP--------KGSRGSPGKPGPQGP---SGDPGPPG- 530
             P      GPPG RG  G+ G  GP        KG +GS G PGP+GP   +GD GPPG 
Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293

Query: 531  --PPGKEGLPGPQGPPGFQGLQGTVGEPG---------VPGPRGLPGLPGVPGMPGP--- 576
               PG  GLPGP+G PGFQG  G  GE G          PGP G  G PGV G PG    
Sbjct: 1294 LGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKI 1353

Query: 577  ---KGPPGPPGPSGAVVPLALQNEP-TPAPEDN--GCPPHWK 612
                G PGPPG  G      +Q EP  P P  N   C P  K
Sbjct: 1354 ISLPGSPGPPGTPGEP---GMQGEPGPPGPPGNLGPCGPRGK 1392



 Score =  144 bits (363), Expect = 3e-34
 Identities = 81/158 (51%), Positives = 91/158 (57%), Gaps = 9/158 (5%)

Query: 439 TILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498
           T + GPPGP GP G  G QGPPG  G+ G+ G+ G PGP G  G  G IG  GPPG    
Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG-IGFPGPPGP--- 707

Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG--LPGPQGPPGFQGLQGTVGEP 556
           KG +G  G KGS G PGK G  G  G PG PG  G+    +PG  G PGF G +G  GE 
Sbjct: 708 KGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767

Query: 557 GVPGPRGLPGLPGVPG---MPGPKGPPGPPGPSGAVVP 591
           G  G  GLPGLPG PG   + GP+G PG PGP G   P
Sbjct: 768 GEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGP 805



 Score =  141 bits (355), Expect = 2e-33
 Identities = 80/171 (46%), Positives = 92/171 (53%), Gaps = 26/171 (15%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQ------KGEKGEPGPPGPA---------GERGPI 487
            GPPGP G  G  G +G PG  G KGQ      KGE+G+ G PGP+         GE G  
Sbjct: 901  GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLK 960

Query: 488  GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD---PGPPGPPGKEGLPGPQGPP 544
            G AG PGE+G +G  G  G KG +G PG  GP GP GD    G PG PG  G+PG  G  
Sbjct: 961  GFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNM 1020

Query: 545  GFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGP--------PGPPGPSG 587
            G  G +G  G  G PG  G PGLPG+ G+ G KG         PGPPGP+G
Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071



 Score =  139 bits (351), Expect = 7e-33
 Identities = 82/187 (43%), Positives = 93/187 (49%), Gaps = 24/187 (12%)

Query: 442  QGPPGPRGPRGDRGSQGP---------------PGPTGNKGQKGEKGEPGPPGPAGERGP 486
            +G PG +G +GD+G+ GP                G  GN G+KG +G PG PG  G +G 
Sbjct: 927  RGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGL 986

Query: 487  IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF 546
             GPAGPPG RG  GS G+ G  G RG PG  G  G  G  G  G  G  G  G  G PG 
Sbjct: 987  PGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGI 1046

Query: 547  QGLQGTVGEPGV-----PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601
             GLQG  GEPG      PGP G  G PG+PG  G KG  G PGP G + P      P  A
Sbjct: 1047 HGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAG----PEGA 1102

Query: 602  PEDNGCP 608
            P   G P
Sbjct: 1103 PGSPGSP 1109



 Score =  139 bits (350), Expect = 9e-33
 Identities = 82/177 (46%), Positives = 94/177 (53%), Gaps = 21/177 (11%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG------PIGPAGP--PG 494
           G PGP GP+GD+G  G  G  G  G+ GE G PG PG  G +G      P GP  P  PG
Sbjct: 700 GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 495 ERGGKGSKGSQGPKGSRGSPGKPG------PQGPSGDPGPP---GPPGK--EGLPGPQGP 543
           ERG  G  G  G  G  G PG PG      P+G  G PGPP   GPPG+  EG  G QG 
Sbjct: 760 ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819

Query: 544 PGFQGLQGTVGEPGVPGPRGLPGLPGV--PGMPGPKGPPGPPGPSGAVVPLALQNEP 598
           PG  GL+G  G  G  GP+G PG+PG+   G PG  G PG PG  G + PL  +  P
Sbjct: 820 PGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876



 Score =  139 bits (349), Expect = 1e-32
 Identities = 78/174 (44%), Positives = 94/174 (54%), Gaps = 13/174 (7%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
           +G PG  G +G  G  G PG  G++G KG +G PG  G  G +G  G  GPPG RG    
Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEY 346

Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP-----QGPPGFQGLQGTVGEP 556
             +   KG  G+PG PGP+G  G  GP GPPG  G PG      +G PG+ GL+G+ GE 
Sbjct: 347 YDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGER 406

Query: 557 GVPG--PRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
           G PG    G PG PG  G PG  G PGPPGP G +V    +  P   P D+G P
Sbjct: 407 GRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIV---FRKGP---PGDHGLP 454



 Score =  138 bits (347), Expect = 2e-32
 Identities = 93/232 (40%), Positives = 109/232 (46%), Gaps = 68/232 (29%)

Query: 441 LQGPPGP---------RGPRGDRGSQGPPGPTGNKGQ---------------------KG 470
           LQG PG           G +G+RG  G  G  G KGQ                     KG
Sbjct: 295 LQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG 354

Query: 471 EKGEPGPPGPAGERGPIGPAGPPGERGGKGSK-----------GSQGPKGSRGSPGK--- 516
           ++G PGPPGP G RGP GP+GPPG  G  GS            G +G KG RG PGK   
Sbjct: 355 DEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAM 414

Query: 517 --PGPQGPSGDPGPPGPPGKEGLPGP----QGPPGFQGLQGTVGEPGVP---GPRGLPGL 567
             PG  G +G PG PG PG  G PG     +GPPG  GL G +G PG+P   GP+G PGL
Sbjct: 415 GTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGL 474

Query: 568 -----------PGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
                      PG+PG+PG  G  G PG  GA     L+  P  +P + G P
Sbjct: 475 LCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA---GLKGSP-GSPGNTGLP 522



 Score =  138 bits (347), Expect = 2e-32
 Identities = 76/163 (46%), Positives = 81/163 (49%), Gaps = 24/163 (14%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQ------------------KGEKGEPGPPGPAGER 484
            G PGP+GP G  G  GPPG  G  G                   KGEKG PG  G  G  
Sbjct: 1274 GHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPP 1333

Query: 485  GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPP 544
            GPIGP GPPG RG  G+       GS G PG PG  G  G+PGPPGPPG  G  GP+G P
Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393

Query: 545  GFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
            G        G+PG PGP G  G  G  G PGP G  G PG  G
Sbjct: 1394 GKD------GKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKG 1430



 Score =  137 bits (345), Expect = 4e-32
 Identities = 73/154 (47%), Positives = 86/154 (55%), Gaps = 9/154 (5%)

Query: 443  GPPGPRGP---RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499
            GPPG  G     G  G+ GPPGP GN G  G++G PG PG  G+RG  G  G  G++G  
Sbjct: 883  GPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNP 942

Query: 500  GSK------GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553
            G        G +G  G +G  G PG +G  G PG PG  G +GLPGP GPPG +G  G+ 
Sbjct: 943  GPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGST 1002

Query: 554  GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
            G PG PG RG+PG  G  GMPG KG  G  G  G
Sbjct: 1003 GNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036



 Score =  135 bits (341), Expect = 1e-31
 Identities = 78/180 (43%), Positives = 90/180 (50%), Gaps = 23/180 (12%)

Query: 442  QGPPGPRGPRGD--------------RGSQGPPGPTGNKGQKGEKGEPGPPG---PAGER 484
            QG  G  GP+GD               GS G PG  G  G  G++G PG PG   P GE 
Sbjct: 829  QGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGED 888

Query: 485  GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQ--- 541
            G IG  G PG  G  G  G+ G  G RGSPG PG +G  G PG  G  G +G PGP    
Sbjct: 889  GVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEIS 948

Query: 542  ---GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598
               G  G  GL+G  G PG  G RG+PG+PG+ G+ G  GP GPPGP G +       EP
Sbjct: 949  HVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEP 1008



 Score =  135 bits (341), Expect = 1e-31
 Identities = 91/228 (39%), Positives = 105/228 (46%), Gaps = 48/228 (21%)

Query: 421  MEEMKLVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQ-----------GPPGPTGN---K 466
            M  M +  SK  +    F    G PG  G  G +G +           GPPGPTG+    
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 467  GQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGP------KGSRGSPGKPGPQ 520
            G  G+KGE G PGP G  GP GP G PG  G  G  G  GP      KG +G  G PG +
Sbjct: 1077 GDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIR 1136

Query: 521  GPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV----PGPRGLP---------GL 567
            GP G PG PG PG  G+ G QG  G  G  G  GE G+    PGPRG P         G 
Sbjct: 1137 GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGA 1196

Query: 568  PGVPGMP---------GPKGP------PGPPGPSGAVVPLALQNEPTP 600
            PG PG+P         GP+GP      PGPPG  GA++P    N   P
Sbjct: 1197 PGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPP 1244



 Score =  135 bits (341), Expect = 1e-31
 Identities = 80/177 (45%), Positives = 89/177 (50%), Gaps = 6/177 (3%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            G PG  GPRGD G QG PG  G KG  G  G  GPPGP G +GP G  G PG        
Sbjct: 1298 GTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLP 1357

Query: 503  GSQGPKGSRGSP---GKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559
            GS GP G+ G P   G+PGP GP G+ GP GP GK G  G  G PG  G +G  G  G P
Sbjct: 1358 GSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEP 1417

Query: 560  GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA-PEDNGCPPHWKNFT 615
            GP G  GLPG+ G  G  G P      G V     Q    P+ PE  G  P +  F+
Sbjct: 1418 GPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPE--GTVPLYSGFS 1472



 Score =  133 bits (335), Expect = 5e-31
 Identities = 84/215 (39%), Positives = 103/215 (47%), Gaps = 53/215 (24%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG- 500
            +G PG +G  G+ G +G  G  G  G KG KG PGP GP G RG +G  G PGE G +G 
Sbjct: 954  KGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGI 1013

Query: 501  -----------SKGSQGP------------------KGSRGSPG-----KPGPQGPSGDP 526
                       SKG +G                   +G +G PG     +PGP GP+GDP
Sbjct: 1014 PGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDP 1073

Query: 527  GPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLP------------GVPGMP 574
            G PG  GK+G  G  GPPG  G  G  G PG PG  GLPG P            G+ G P
Sbjct: 1074 GLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPP 1133

Query: 575  GPKGPPGPPGPSGAVVPLALQNE------PTPAPE 603
            G +GPPG PG  G+  P+ ++ +      P PA E
Sbjct: 1134 GIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE 1168



 Score =  132 bits (332), Expect = 1e-30
 Identities = 69/159 (43%), Positives = 81/159 (50%), Gaps = 20/159 (12%)

Query: 446 GPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQ 505
           G +G +G++G  GPPG  G KG  G +G PGP GP G  G  G  G  G RG  G  G  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 506 GPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV------------ 553
           G  G  G+PG  GP G  G PG  G  G++G PG  G  G+ G+ G              
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 554 --------GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPG 584
                   G+PG+PG  G  GLPG PG PGP GPPGPPG
Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPG 201



 Score =  129 bits (325), Expect = 8e-30
 Identities = 72/154 (46%), Positives = 82/154 (53%), Gaps = 26/154 (16%)

Query: 464 GNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPS 523
           G KG+KGEKG PGPPG  G++G  GP G PG +G KG  G  G  GS+G  G  G  G S
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 524 GDPGPPGPPGK---------EGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGL------- 567
           G PG PG PG           G  G +G  GF GL GT+G PG+PG  GL G        
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 568 ----------PGVPGMPGPKGPPGPPGPSGAVVP 591
                     PG+PG PGP+G PGPPG  G V P
Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP 196



 Score =  129 bits (324), Expect = 1e-29
 Identities = 82/194 (42%), Positives = 90/194 (46%), Gaps = 31/194 (15%)

Query: 441 LQGPPGPRGPRGDRG-SQGPPGPTGNKGQKGEKGEPGPPGPAGERG-----------PIG 488
           L G PGP GP GD    +GPPG  G  G  G  G PG  GP GE G           P G
Sbjct: 428 LPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPG 487

Query: 489 PAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPG-------PQ 541
             G PG  G KG  G QG  G +GSPG PG  G  G PG PG  G  GL G       P+
Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPE 547

Query: 542 GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKG------------PPGPPGPSGAV 589
           G  G  G  G  G+PG  G  G+PG PGV G+PGPKG            PPG PG  G+ 
Sbjct: 548 GQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSP 607

Query: 590 VPLALQNEPTPAPE 603
            P      P   P+
Sbjct: 608 GPAGPAGPPGYGPQ 621



 Score =  125 bits (315), Expect = 1e-28
 Identities = 79/186 (42%), Positives = 88/186 (47%), Gaps = 34/186 (18%)

Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQK------GEKGEPGPPGPAGERGPIGP 489
           K FT  +G PGP+GP   +G  G PG TG+KG +      G  G PG PG  G  GP G 
Sbjct: 63  KGFTGPEGLPGPQGP---KGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGL 119

Query: 490 AGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPP-----------GPPGKEGLP 538
            G PG  G KG +G  G  G+ G PG PG  G  G  G P           G PG  G P
Sbjct: 120 VGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAP 179

Query: 539 GPQGPPGFQGLQGTVGEPGVPGPRGLPG--------------LPGVPGMPGPKGPPGPPG 584
           GPQG PG  G  G VG PG PG  G PG              + G  G  G KG  GPPG
Sbjct: 180 GPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPG 239

Query: 585 PSGAVV 590
           P G V+
Sbjct: 240 PPGTVI 245



 Score =  124 bits (312), Expect = 2e-28
 Identities = 75/184 (40%), Positives = 89/184 (48%), Gaps = 39/184 (21%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGN--------KGQKGEKGEPGPPGPAGE-----RGPIGP 489
           GPPGP G  G  G+ GP GP G+        KG++G KG  GPPGP G       GP   
Sbjct: 195 GPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNR 254

Query: 490 AGPPGERGGKGSKGSQGPKG-----------SRGSPGKPGPQGPSGDPGPPGPPGKEGL- 537
               GE+G KG+ G  GP G            +G+PG PG QG  G  G PG PG EG+ 
Sbjct: 255 TDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVK 314

Query: 538 -----PGPQGPPGFQGLQGTVGEPGVPGP---------RGLPGLPGVPGMPGPKGPPGPP 583
                PG  G  G +G +G +G PG  GP         +G  G PG PG  G +GP GP 
Sbjct: 315 GNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPS 374

Query: 584 GPSG 587
           GP G
Sbjct: 375 GPPG 378



 Score =  124 bits (311), Expect = 3e-28
 Identities = 77/176 (43%), Positives = 85/176 (48%), Gaps = 36/176 (20%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP-------IGPAGPP 493
           ++G PG +G  G +GS G PG TG  G  G  G  G PG  GE+G        +G  G P
Sbjct: 497 VKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDP 556

Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGPQGP------SGDPGPPGPPGKEGLPGPQGPPGFQ 547
           G RG  G KG  G  G+ G  G PGP+G        GD GPPG PG  G PGP GP G  
Sbjct: 557 GLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPP 616

Query: 548 GLQGTVGEPGVPGPRGLPGLPGVPGMPGP----------------KGPPGPPGPSG 587
           G  G  GEPG      L G  GVPG PGP                 GPPGPPGP G
Sbjct: 617 GY-GPQGEPG------LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665



 Score =  124 bits (310), Expect = 4e-28
 Identities = 89/233 (38%), Positives = 99/233 (42%), Gaps = 67/233 (28%)

Query: 443 GPPGP-------RGPRGDRGSQGPPGPTGNKGQKGEKGEPG-----------PPGPAGER 484
           GPPGP       +GP GD G  G  G  G  G  G KGEPG           PPG  G  
Sbjct: 433 GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLP 492

Query: 485 GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPG----------PPGPPGK 534
           G  G  G PG +G  G KGS G  G+ G PG PG  G  GDPG          P G  G 
Sbjct: 493 GLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGV 552

Query: 535 EGLPGPQGPPGFQGLQGTVGEPGV---PGPRGL------------PGLPGVPGMPGPKGP 579
            G PG +G PG +GL G  G PGV   PGP+G             PG PG PG PGP GP
Sbjct: 553 PGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGP 612

Query: 580 -----------------------PGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609
                                  PGPPG +G    L++ + P P P     PP
Sbjct: 613 AGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSV-STPVPGPPGPPGPP 664



 Score =  122 bits (306), Expect = 1e-27
 Identities = 77/179 (43%), Positives = 90/179 (50%), Gaps = 34/179 (18%)

Query: 443 GPPGPRGPRGDRGS------QGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPA------ 490
           G PG RG  G+ G        G PG  GN+G  G +G+PG PGP GE+GP G        
Sbjct: 756 GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815

Query: 491 --GPPGERGGKGSKGSQGPKGSRGSPGKPGPQ-----GPSGDPGPPG------PPGKEGL 537
             G PG  G KG +G +G  G +G PG PG       G +G PG PG      P G+ G 
Sbjct: 816 AQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGY 875

Query: 538 PGPQG---PPGFQGLQGTVGEPGV---PGPRGLPGLP---GVPGMPGPKGPPGPPGPSG 587
           PG  G   PPG  G+ G +G PG    PGP G PG P   G PG+PG KG  G PG  G
Sbjct: 876 PGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKG 934



 Score =  117 bits (292), Expect = 5e-26
 Identities = 74/173 (42%), Positives = 82/173 (47%), Gaps = 36/173 (20%)

Query: 451 RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGE---RGPIGPAGPPGERGGK--GSKGSQ 505
           +GD G  G PGP G  G  G  G  GPPGP G     G +GP GP G  G +  G KG +
Sbjct: 170 KGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGER 229

Query: 506 GPKGSRGSPGKPGP-----------------QGPSGDPGPPGPPGKEGLPGP-----QGP 543
           G KG  G PG PG                  +G  G  G PGPPG  GLPG      +G 
Sbjct: 230 GVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGA 289

Query: 544 PGFQGLQGTVGEPGVP---------GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           PG  GLQG  G+ GVP         G RG PGL G  G+ G KG  GPPG  G
Sbjct: 290 PGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRG 342



 Score =  115 bits (289), Expect = 1e-25
 Identities = 80/211 (37%), Positives = 91/211 (43%), Gaps = 32/211 (15%)

Query: 426 LVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG 485
           L  SK  + I       G PG  G  G+ G  G  G  G  G KGE+G PG PG  G  G
Sbjct: 86  LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145

Query: 486 PIGPAGPPGERGGKG--------SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL 537
             G AG  G++G           +KG  G  G+ G  G PGP G  G  GPPGPPG  G 
Sbjct: 146 IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205

Query: 538 PGPQGPPGFQGLQG--TVGEPGVPGPRGLPGLPGVPGM--------------------PG 575
           PG  GP G +G  G   +G  G  G +GL G PG PG                      G
Sbjct: 206 PGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKG 265

Query: 576 PKGPPGPPGPSGAVVPLALQNEPTPAPEDNG 606
             G PGPPGPSG  +P         AP D G
Sbjct: 266 AMGEPGPPGPSG--LPGESYGSEKGAPGDPG 294


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
           sapiens]
          Length = 1670

 Score =  166 bits (421), Expect = 6e-41
 Identities = 87/173 (50%), Positives = 104/173 (60%), Gaps = 16/173 (9%)

Query: 441 LQGPPGPRGPRGDRGS---QGPPGPTGN---KGQKGEKGEPGPPGPAGERGPIGPAGPPG 494
           L+G PG +G  G  G+   +G PGP G     G+KG++G PG PG  G  GP GPAGPPG
Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617

Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD-------PGPPGPPGKEGLPGPQGPPGFQ 547
             G +G  G QG +G  G+PG PG  GP G+       PGPPGPPG  G PGPQGPPG  
Sbjct: 618 Y-GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIP 676

Query: 548 GLQGTVGEPGVPGPRGLPGLPGV--PGMPGPKGPPGPPGPSGAVVPLALQNEP 598
           G  G  G+PG+PGP G PG+PG+  PG PGPKG  G PG  G++       EP
Sbjct: 677 GSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEP 729



 Score =  150 bits (380), Expect = 3e-36
 Identities = 88/193 (45%), Positives = 96/193 (49%), Gaps = 20/193 (10%)

Query: 432  GQLIKNFTILQGPPGPRGPRGDRGSQGPPGP--TGNKGQKGEKGEPGPPGPAGERGPIGP 489
            G +I   T  +GPPG RG  G  G  GPPG    G KG KG  G PGP GP G  G +GP
Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP 1290

Query: 490  AGP---------PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG---- 536
             G          PG RG  G +G  G KG +G+PG  G  GP G  GP GPPG  G    
Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGT 1350

Query: 537  -----LPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
                 LPG  GPPG  G  G  GEPG PGP G  G  G  G PG  G PG PGP+G    
Sbjct: 1351 LKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGN 1410

Query: 592  LALQNEPTPAPED 604
               + EP PA  D
Sbjct: 1411 KGSKGEPGPAGSD 1423



 Score =  149 bits (376), Expect = 9e-36
 Identities = 87/209 (41%), Positives = 98/209 (46%), Gaps = 42/209 (20%)

Query: 435  IKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG------ 488
            +K    L GP GP GPRGD GS G PG  G +G  G  G  G PG  G+RG +G      
Sbjct: 980  LKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAG 1039

Query: 489  -----------------------PAGPPGERGGKGSKGSQGPKGSRGSPGKPG---PQGP 522
                                     GPPG  G  G  G  G KG  G PG PG   P GP
Sbjct: 1040 RPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGP 1099

Query: 523  SGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGP------ 576
             G PG PG PG  G PGP G  GF+G++G +G PG+ GP   PGLPG PG PGP      
Sbjct: 1100 EGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGP---PGLPGFPGSPGPMGIRGD 1156

Query: 577  KGPPGPPGPSGAVVPLALQNEPTPAPEDN 605
            +G  G PGP+G      L   P P P  N
Sbjct: 1157 QGRDGIPGPAGEKGETGLLRAP-PGPRGN 1184



 Score =  145 bits (367), Expect = 1e-34
 Identities = 98/222 (44%), Positives = 109/222 (49%), Gaps = 52/222 (23%)

Query: 440  ILQGPPGPRG------PRGDRGSQGPPGPTGNKGQKGEKGEPGP------PGPAGERGPI 487
            +L+ PPGPRG       +GDRG+ G PG  G KG  G+ G  GP      PGP G  G I
Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233

Query: 488  GPA-----GPPGERGGKGSKGSQGP--------KGSRGSPGKPGPQGP---SGDPGPPG- 530
             P      GPPG RG  G+ G  GP        KG +GS G PGP+GP   +GD GPPG 
Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293

Query: 531  --PPGKEGLPGPQGPPGFQGLQGTVGEPG---------VPGPRGLPGLPGVPGMPGP--- 576
               PG  GLPGP+G PGFQG  G  GE G          PGP G  G PGV G PG    
Sbjct: 1294 LGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKI 1353

Query: 577  ---KGPPGPPGPSGAVVPLALQNEP-TPAPEDN--GCPPHWK 612
                G PGPPG  G      +Q EP  P P  N   C P  K
Sbjct: 1354 ISLPGSPGPPGTPGEP---GMQGEPGPPGPPGNLGPCGPRGK 1392



 Score =  144 bits (363), Expect = 3e-34
 Identities = 81/158 (51%), Positives = 91/158 (57%), Gaps = 9/158 (5%)

Query: 439 TILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498
           T + GPPGP GP G  G QGPPG  G+ G+ G+ G PGP G  G  G IG  GPPG    
Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG-IGFPGPPGP--- 707

Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG--LPGPQGPPGFQGLQGTVGEP 556
           KG +G  G KGS G PGK G  G  G PG PG  G+    +PG  G PGF G +G  GE 
Sbjct: 708 KGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767

Query: 557 GVPGPRGLPGLPGVPG---MPGPKGPPGPPGPSGAVVP 591
           G  G  GLPGLPG PG   + GP+G PG PGP G   P
Sbjct: 768 GEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGP 805



 Score =  141 bits (355), Expect = 2e-33
 Identities = 80/171 (46%), Positives = 92/171 (53%), Gaps = 26/171 (15%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQ------KGEKGEPGPPGPA---------GERGPI 487
            GPPGP G  G  G +G PG  G KGQ      KGE+G+ G PGP+         GE G  
Sbjct: 901  GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLK 960

Query: 488  GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD---PGPPGPPGKEGLPGPQGPP 544
            G AG PGE+G +G  G  G KG +G PG  GP GP GD    G PG PG  G+PG  G  
Sbjct: 961  GFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNM 1020

Query: 545  GFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGP--------PGPPGPSG 587
            G  G +G  G  G PG  G PGLPG+ G+ G KG         PGPPGP+G
Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071



 Score =  139 bits (351), Expect = 7e-33
 Identities = 82/187 (43%), Positives = 93/187 (49%), Gaps = 24/187 (12%)

Query: 442  QGPPGPRGPRGDRGSQGP---------------PGPTGNKGQKGEKGEPGPPGPAGERGP 486
            +G PG +G +GD+G+ GP                G  GN G+KG +G PG PG  G +G 
Sbjct: 927  RGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGL 986

Query: 487  IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF 546
             GPAGPPG RG  GS G+ G  G RG PG  G  G  G  G  G  G  G  G  G PG 
Sbjct: 987  PGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGI 1046

Query: 547  QGLQGTVGEPGV-----PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601
             GLQG  GEPG      PGP G  G PG+PG  G KG  G PGP G + P      P  A
Sbjct: 1047 HGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAG----PEGA 1102

Query: 602  PEDNGCP 608
            P   G P
Sbjct: 1103 PGSPGSP 1109



 Score =  139 bits (350), Expect = 9e-33
 Identities = 82/177 (46%), Positives = 94/177 (53%), Gaps = 21/177 (11%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG------PIGPAGP--PG 494
           G PGP GP+GD+G  G  G  G  G+ GE G PG PG  G +G      P GP  P  PG
Sbjct: 700 GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 495 ERGGKGSKGSQGPKGSRGSPGKPG------PQGPSGDPGPP---GPPGK--EGLPGPQGP 543
           ERG  G  G  G  G  G PG PG      P+G  G PGPP   GPPG+  EG  G QG 
Sbjct: 760 ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819

Query: 544 PGFQGLQGTVGEPGVPGPRGLPGLPGV--PGMPGPKGPPGPPGPSGAVVPLALQNEP 598
           PG  GL+G  G  G  GP+G PG+PG+   G PG  G PG PG  G + PL  +  P
Sbjct: 820 PGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876



 Score =  139 bits (349), Expect = 1e-32
 Identities = 78/174 (44%), Positives = 94/174 (54%), Gaps = 13/174 (7%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
           +G PG  G +G  G  G PG  G++G KG +G PG  G  G +G  G  GPPG RG    
Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEY 346

Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP-----QGPPGFQGLQGTVGEP 556
             +   KG  G+PG PGP+G  G  GP GPPG  G PG      +G PG+ GL+G+ GE 
Sbjct: 347 YDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGER 406

Query: 557 GVPG--PRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
           G PG    G PG PG  G PG  G PGPPGP G +V    +  P   P D+G P
Sbjct: 407 GRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIV---FRKGP---PGDHGLP 454



 Score =  138 bits (347), Expect = 2e-32
 Identities = 93/232 (40%), Positives = 109/232 (46%), Gaps = 68/232 (29%)

Query: 441 LQGPPGP---------RGPRGDRGSQGPPGPTGNKGQ---------------------KG 470
           LQG PG           G +G+RG  G  G  G KGQ                     KG
Sbjct: 295 LQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG 354

Query: 471 EKGEPGPPGPAGERGPIGPAGPPGERGGKGSK-----------GSQGPKGSRGSPGK--- 516
           ++G PGPPGP G RGP GP+GPPG  G  GS            G +G KG RG PGK   
Sbjct: 355 DEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAM 414

Query: 517 --PGPQGPSGDPGPPGPPGKEGLPGP----QGPPGFQGLQGTVGEPGVP---GPRGLPGL 567
             PG  G +G PG PG PG  G PG     +GPPG  GL G +G PG+P   GP+G PGL
Sbjct: 415 GTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGL 474

Query: 568 -----------PGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
                      PG+PG+PG  G  G PG  GA     L+  P  +P + G P
Sbjct: 475 LCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA---GLKGSP-GSPGNTGLP 522



 Score =  138 bits (347), Expect = 2e-32
 Identities = 76/163 (46%), Positives = 81/163 (49%), Gaps = 24/163 (14%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQ------------------KGEKGEPGPPGPAGER 484
            G PGP+GP G  G  GPPG  G  G                   KGEKG PG  G  G  
Sbjct: 1274 GHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPP 1333

Query: 485  GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPP 544
            GPIGP GPPG RG  G+       GS G PG PG  G  G+PGPPGPPG  G  GP+G P
Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393

Query: 545  GFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
            G        G+PG PGP G  G  G  G PGP G  G PG  G
Sbjct: 1394 GKD------GKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKG 1430



 Score =  137 bits (345), Expect = 4e-32
 Identities = 73/154 (47%), Positives = 86/154 (55%), Gaps = 9/154 (5%)

Query: 443  GPPGPRGP---RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499
            GPPG  G     G  G+ GPPGP GN G  G++G PG PG  G+RG  G  G  G++G  
Sbjct: 883  GPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNP 942

Query: 500  GSK------GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553
            G        G +G  G +G  G PG +G  G PG PG  G +GLPGP GPPG +G  G+ 
Sbjct: 943  GPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGST 1002

Query: 554  GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
            G PG PG RG+PG  G  GMPG KG  G  G  G
Sbjct: 1003 GNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036



 Score =  135 bits (341), Expect = 1e-31
 Identities = 78/180 (43%), Positives = 90/180 (50%), Gaps = 23/180 (12%)

Query: 442  QGPPGPRGPRGD--------------RGSQGPPGPTGNKGQKGEKGEPGPPG---PAGER 484
            QG  G  GP+GD               GS G PG  G  G  G++G PG PG   P GE 
Sbjct: 829  QGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGED 888

Query: 485  GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQ--- 541
            G IG  G PG  G  G  G+ G  G RGSPG PG +G  G PG  G  G +G PGP    
Sbjct: 889  GVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEIS 948

Query: 542  ---GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598
               G  G  GL+G  G PG  G RG+PG+PG+ G+ G  GP GPPGP G +       EP
Sbjct: 949  HVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEP 1008



 Score =  135 bits (341), Expect = 1e-31
 Identities = 91/228 (39%), Positives = 105/228 (46%), Gaps = 48/228 (21%)

Query: 421  MEEMKLVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQ-----------GPPGPTGN---K 466
            M  M +  SK  +    F    G PG  G  G +G +           GPPGPTG+    
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 467  GQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGP------KGSRGSPGKPGPQ 520
            G  G+KGE G PGP G  GP GP G PG  G  G  G  GP      KG +G  G PG +
Sbjct: 1077 GDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIR 1136

Query: 521  GPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV----PGPRGLP---------GL 567
            GP G PG PG PG  G+ G QG  G  G  G  GE G+    PGPRG P         G 
Sbjct: 1137 GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGA 1196

Query: 568  PGVPGMP---------GPKGP------PGPPGPSGAVVPLALQNEPTP 600
            PG PG+P         GP+GP      PGPPG  GA++P    N   P
Sbjct: 1197 PGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPP 1244



 Score =  135 bits (341), Expect = 1e-31
 Identities = 80/177 (45%), Positives = 89/177 (50%), Gaps = 6/177 (3%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            G PG  GPRGD G QG PG  G KG  G  G  GPPGP G +GP G  G PG        
Sbjct: 1298 GTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLP 1357

Query: 503  GSQGPKGSRGSP---GKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559
            GS GP G+ G P   G+PGP GP G+ GP GP GK G  G  G PG  G +G  G  G P
Sbjct: 1358 GSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEP 1417

Query: 560  GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA-PEDNGCPPHWKNFT 615
            GP G  GLPG+ G  G  G P      G V     Q    P+ PE  G  P +  F+
Sbjct: 1418 GPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPE--GTVPLYSGFS 1472



 Score =  133 bits (335), Expect = 5e-31
 Identities = 84/215 (39%), Positives = 103/215 (47%), Gaps = 53/215 (24%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG- 500
            +G PG +G  G+ G +G  G  G  G KG KG PGP GP G RG +G  G PGE G +G 
Sbjct: 954  KGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGI 1013

Query: 501  -----------SKGSQGP------------------KGSRGSPG-----KPGPQGPSGDP 526
                       SKG +G                   +G +G PG     +PGP GP+GDP
Sbjct: 1014 PGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDP 1073

Query: 527  GPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLP------------GVPGMP 574
            G PG  GK+G  G  GPPG  G  G  G PG PG  GLPG P            G+ G P
Sbjct: 1074 GLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPP 1133

Query: 575  GPKGPPGPPGPSGAVVPLALQNE------PTPAPE 603
            G +GPPG PG  G+  P+ ++ +      P PA E
Sbjct: 1134 GIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE 1168



 Score =  132 bits (332), Expect = 1e-30
 Identities = 69/159 (43%), Positives = 81/159 (50%), Gaps = 20/159 (12%)

Query: 446 GPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQ 505
           G +G +G++G  GPPG  G KG  G +G PGP GP G  G  G  G  G RG  G  G  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 506 GPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV------------ 553
           G  G  G+PG  GP G  G PG  G  G++G PG  G  G+ G+ G              
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 554 --------GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPG 584
                   G+PG+PG  G  GLPG PG PGP GPPGPPG
Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPG 201



 Score =  129 bits (325), Expect = 8e-30
 Identities = 72/154 (46%), Positives = 82/154 (53%), Gaps = 26/154 (16%)

Query: 464 GNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPS 523
           G KG+KGEKG PGPPG  G++G  GP G PG +G KG  G  G  GS+G  G  G  G S
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 524 GDPGPPGPPGK---------EGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGL------- 567
           G PG PG PG           G  G +G  GF GL GT+G PG+PG  GL G        
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 568 ----------PGVPGMPGPKGPPGPPGPSGAVVP 591
                     PG+PG PGP+G PGPPG  G V P
Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP 196



 Score =  129 bits (324), Expect = 1e-29
 Identities = 82/194 (42%), Positives = 90/194 (46%), Gaps = 31/194 (15%)

Query: 441 LQGPPGPRGPRGDRG-SQGPPGPTGNKGQKGEKGEPGPPGPAGERG-----------PIG 488
           L G PGP GP GD    +GPPG  G  G  G  G PG  GP GE G           P G
Sbjct: 428 LPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPG 487

Query: 489 PAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPG-------PQ 541
             G PG  G KG  G QG  G +GSPG PG  G  G PG PG  G  GL G       P+
Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPE 547

Query: 542 GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKG------------PPGPPGPSGAV 589
           G  G  G  G  G+PG  G  G+PG PGV G+PGPKG            PPG PG  G+ 
Sbjct: 548 GQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSP 607

Query: 590 VPLALQNEPTPAPE 603
            P      P   P+
Sbjct: 608 GPAGPAGPPGYGPQ 621



 Score =  125 bits (315), Expect = 1e-28
 Identities = 79/186 (42%), Positives = 88/186 (47%), Gaps = 34/186 (18%)

Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQK------GEKGEPGPPGPAGERGPIGP 489
           K FT  +G PGP+GP   +G  G PG TG+KG +      G  G PG PG  G  GP G 
Sbjct: 63  KGFTGPEGLPGPQGP---KGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGL 119

Query: 490 AGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPP-----------GPPGKEGLP 538
            G PG  G KG +G  G  G+ G PG PG  G  G  G P           G PG  G P
Sbjct: 120 VGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAP 179

Query: 539 GPQGPPGFQGLQGTVGEPGVPGPRGLPG--------------LPGVPGMPGPKGPPGPPG 584
           GPQG PG  G  G VG PG PG  G PG              + G  G  G KG  GPPG
Sbjct: 180 GPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPG 239

Query: 585 PSGAVV 590
           P G V+
Sbjct: 240 PPGTVI 245



 Score =  124 bits (312), Expect = 2e-28
 Identities = 75/184 (40%), Positives = 89/184 (48%), Gaps = 39/184 (21%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGN--------KGQKGEKGEPGPPGPAGE-----RGPIGP 489
           GPPGP G  G  G+ GP GP G+        KG++G KG  GPPGP G       GP   
Sbjct: 195 GPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNR 254

Query: 490 AGPPGERGGKGSKGSQGPKG-----------SRGSPGKPGPQGPSGDPGPPGPPGKEGL- 537
               GE+G KG+ G  GP G            +G+PG PG QG  G  G PG PG EG+ 
Sbjct: 255 TDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVK 314

Query: 538 -----PGPQGPPGFQGLQGTVGEPGVPGP---------RGLPGLPGVPGMPGPKGPPGPP 583
                PG  G  G +G +G +G PG  GP         +G  G PG PG  G +GP GP 
Sbjct: 315 GNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPS 374

Query: 584 GPSG 587
           GP G
Sbjct: 375 GPPG 378



 Score =  124 bits (311), Expect = 3e-28
 Identities = 77/176 (43%), Positives = 85/176 (48%), Gaps = 36/176 (20%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP-------IGPAGPP 493
           ++G PG +G  G +GS G PG TG  G  G  G  G PG  GE+G        +G  G P
Sbjct: 497 VKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDP 556

Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGPQGP------SGDPGPPGPPGKEGLPGPQGPPGFQ 547
           G RG  G KG  G  G+ G  G PGP+G        GD GPPG PG  G PGP GP G  
Sbjct: 557 GLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPP 616

Query: 548 GLQGTVGEPGVPGPRGLPGLPGVPGMPGP----------------KGPPGPPGPSG 587
           G  G  GEPG      L G  GVPG PGP                 GPPGPPGP G
Sbjct: 617 GY-GPQGEPG------LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665



 Score =  124 bits (310), Expect = 4e-28
 Identities = 89/233 (38%), Positives = 99/233 (42%), Gaps = 67/233 (28%)

Query: 443 GPPGP-------RGPRGDRGSQGPPGPTGNKGQKGEKGEPG-----------PPGPAGER 484
           GPPGP       +GP GD G  G  G  G  G  G KGEPG           PPG  G  
Sbjct: 433 GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLP 492

Query: 485 GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPG----------PPGPPGK 534
           G  G  G PG +G  G KGS G  G+ G PG PG  G  GDPG          P G  G 
Sbjct: 493 GLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGV 552

Query: 535 EGLPGPQGPPGFQGLQGTVGEPGV---PGPRGL------------PGLPGVPGMPGPKGP 579
            G PG +G PG +GL G  G PGV   PGP+G             PG PG PG PGP GP
Sbjct: 553 PGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGP 612

Query: 580 -----------------------PGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609
                                  PGPPG +G    L++ + P P P     PP
Sbjct: 613 AGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSV-STPVPGPPGPPGPP 664



 Score =  122 bits (306), Expect = 1e-27
 Identities = 77/179 (43%), Positives = 90/179 (50%), Gaps = 34/179 (18%)

Query: 443 GPPGPRGPRGDRGS------QGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPA------ 490
           G PG RG  G+ G        G PG  GN+G  G +G+PG PGP GE+GP G        
Sbjct: 756 GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815

Query: 491 --GPPGERGGKGSKGSQGPKGSRGSPGKPGPQ-----GPSGDPGPPG------PPGKEGL 537
             G PG  G KG +G +G  G +G PG PG       G +G PG PG      P G+ G 
Sbjct: 816 AQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGY 875

Query: 538 PGPQG---PPGFQGLQGTVGEPGV---PGPRGLPGLP---GVPGMPGPKGPPGPPGPSG 587
           PG  G   PPG  G+ G +G PG    PGP G PG P   G PG+PG KG  G PG  G
Sbjct: 876 PGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKG 934



 Score =  117 bits (292), Expect = 5e-26
 Identities = 74/173 (42%), Positives = 82/173 (47%), Gaps = 36/173 (20%)

Query: 451 RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGE---RGPIGPAGPPGERGGK--GSKGSQ 505
           +GD G  G PGP G  G  G  G  GPPGP G     G +GP GP G  G +  G KG +
Sbjct: 170 KGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGER 229

Query: 506 GPKGSRGSPGKPGP-----------------QGPSGDPGPPGPPGKEGLPGP-----QGP 543
           G KG  G PG PG                  +G  G  G PGPPG  GLPG      +G 
Sbjct: 230 GVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGA 289

Query: 544 PGFQGLQGTVGEPGVP---------GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           PG  GLQG  G+ GVP         G RG PGL G  G+ G KG  GPPG  G
Sbjct: 290 PGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRG 342



 Score =  115 bits (289), Expect = 1e-25
 Identities = 80/211 (37%), Positives = 91/211 (43%), Gaps = 32/211 (15%)

Query: 426 LVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG 485
           L  SK  + I       G PG  G  G+ G  G  G  G  G KGE+G PG PG  G  G
Sbjct: 86  LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145

Query: 486 PIGPAGPPGERGGKG--------SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL 537
             G AG  G++G           +KG  G  G+ G  G PGP G  G  GPPGPPG  G 
Sbjct: 146 IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205

Query: 538 PGPQGPPGFQGLQG--TVGEPGVPGPRGLPGLPGVPGM--------------------PG 575
           PG  GP G +G  G   +G  G  G +GL G PG PG                      G
Sbjct: 206 PGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKG 265

Query: 576 PKGPPGPPGPSGAVVPLALQNEPTPAPEDNG 606
             G PGPPGPSG  +P         AP D G
Sbjct: 266 AMGEPGPPGPSG--LPGESYGSEKGAPGDPG 294


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  166 bits (420), Expect = 7e-41
 Identities = 91/198 (45%), Positives = 106/198 (53%), Gaps = 10/198 (5%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---PAGPPGERGG 498
            +G  GP GP G  G+ G PGP G  G+ G++GE GP GPAG  GP+G   PAGP G RG 
Sbjct: 1036 RGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGD 1095

Query: 499  KGSKGSQGP---KGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGE 555
            KG  G QG    KG RG  G  GP GP G PG  GP G  G  GP+GPPG  G  G  G 
Sbjct: 1096 KGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGL 1155

Query: 556  PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPPHWKNFT 615
             G+PGP G PG  G  G  GP GPPGPPGP G   P +   + +  P+    PP  K   
Sbjct: 1156 NGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQ----PPQEKAHD 1211

Query: 616  DKCYYFSVEKEIFEDAKL 633
               YY + +  +  D  L
Sbjct: 1212 GGRYYRADDANVVRDRDL 1229



 Score =  165 bits (418), Expect = 1e-40
 Identities = 92/191 (48%), Positives = 100/191 (52%), Gaps = 23/191 (12%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG------------PPGPAGERGPIG 488
           +QGPPGP G  G RG++G PGPTG  G  GE+G PG            P GPAGERG  G
Sbjct: 456 VQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPG 515

Query: 489 PAGP---PGERGGKGSKGSQGPKGSRGSPGKPGPQG------PSGDPGPPGPPGKEGLPG 539
           PAGP   PGE G  G  G  G KG  GSPG PGP G      P+G  G PGPPG  G  G
Sbjct: 516 PAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARG 575

Query: 540 PQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPT 599
             G  GF G +G  GEPG  G RG+PG PG  G  G  G  G  GP G   P   + E  
Sbjct: 576 QAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQG 635

Query: 600 PA--PEDNGCP 608
           PA  P   G P
Sbjct: 636 PAGSPGFQGLP 646



 Score =  165 bits (417), Expect = 2e-40
 Identities = 87/197 (44%), Positives = 99/197 (50%), Gaps = 39/197 (19%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP---------- 492
            GPPGP GP G  G +GP G TG  G+ GE G PGPPGPAGE+G  G  GP          
Sbjct: 893  GPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQ 952

Query: 493  -----------PGERGGK---------GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPP 532
                       PG+RG +         G  G QGP G+ G  G PGP GP G  GPPG  
Sbjct: 953  GIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGES 1012

Query: 533  GKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGP---------PGPP 583
            G+EG PG +G PG  G  G  G+ G  GP G PG PG PG PGP GP          GP 
Sbjct: 1013 GREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPA 1072

Query: 584  GPSGAVVPLALQNEPTP 600
            GP+G V P+  +    P
Sbjct: 1073 GPAGPVGPVGARGPAGP 1089



 Score =  164 bits (414), Expect = 4e-40
 Identities = 80/148 (54%), Positives = 88/148 (59%), Gaps = 3/148 (2%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           GPPGP G  G  G+ G PG  G  G  G KG+ GPPGPAG  GP GP G  G  G KG++
Sbjct: 806 GPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGAR 865

Query: 503 GSQGPKGSRGSPG---KPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559
           GS GP G+ G PG   + GP GPSG+ GPPGPPG  G  G +GP G  G  G  GE G P
Sbjct: 866 GSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPP 925

Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           GP G  G  G PG  GP G PG PGP G
Sbjct: 926 GPPGPAGEKGSPGADGPAGAPGTPGPQG 953



 Score =  162 bits (411), Expect = 8e-40
 Identities = 82/157 (52%), Positives = 90/157 (57%), Gaps = 15/157 (9%)

Query: 443  GPPGP------RGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGER 496
            GPPGP       G +G RGS GPPG TG  G  G  G   PPGP+G  GP GP GP G+ 
Sbjct: 848  GPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVG---PPGPSGNAGPPGPPGPAGKE 904

Query: 497  GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
            GGKG +G  GP G  G  G PGP GP+G+ G PG  G  G PG  GP G  G +G VG P
Sbjct: 905  GGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLP 964

Query: 557  GVPGPRGLPGLPGVPGMPGPKGPP------GPPGPSG 587
            G  G RG PGLPG  G PG +GP       GPPGP G
Sbjct: 965  GQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMG 1001



 Score =  160 bits (405), Expect = 4e-39
 Identities = 84/186 (45%), Positives = 97/186 (52%), Gaps = 27/186 (14%)

Query: 443 GPPGPRGPRGD---------RGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPP 493
           GPPGP GP G          +G  GP GP G++G +G +GEPGPPGPAG  GP G  G  
Sbjct: 332 GPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGAD 391

Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP------------- 540
           G+ G KG+ G+ G  G+ G PG  GP GP G  GPPGP G  G PG              
Sbjct: 392 GQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEP 451

Query: 541 -----QGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQ 595
                QGPPG  G +G  G  G PGP GLPG PG  G PG +G PG  G +G   P   +
Sbjct: 452 GPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGER 511

Query: 596 NEPTPA 601
             P PA
Sbjct: 512 GSPGPA 517



 Score =  159 bits (403), Expect = 7e-39
 Identities = 80/167 (47%), Positives = 92/167 (55%), Gaps = 9/167 (5%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG---PPGPAGERGPIGPAGPPGERGGK 499
           G PG  GP G RG  GPPG  G+ G+ G+ G PG   PPGP G RG  G AG PG +G +
Sbjct: 209 GEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHR 268

Query: 500 G------SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553
           G      +KG  GP G +G PG PG  G  G  GP G PG+ G PG  GP G +G  G  
Sbjct: 269 GFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGAT 328

Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP 600
           G  G PGP G  G PG PG  G KG  GP GP G+  P  ++ EP P
Sbjct: 329 GAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGP 375



 Score =  159 bits (403), Expect = 7e-39
 Identities = 81/157 (51%), Positives = 88/157 (56%), Gaps = 18/157 (11%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG------------PIGPA 490
           GP GP+G  G  G  G PG  G +G  GE+G PG PGPAG RG            P GPA
Sbjct: 281 GPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPA 340

Query: 491 GPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQ 550
           GPPG  G  G+KG  GP+G RGS G   PQG  G+PGPPGP G  G   P G PG  G  
Sbjct: 341 GPPGFPGAVGAKGEAGPQGPRGSEG---PQGVRGEPGPPGPAGAAG---PAGNPGADGQP 394

Query: 551 GTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           G  G  G PG  G PG PG  G  GP+GP GPPGP G
Sbjct: 395 GAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKG 431



 Score =  159 bits (402), Expect = 9e-39
 Identities = 80/158 (50%), Positives = 89/158 (56%), Gaps = 9/158 (5%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQ------KGEKGEPGPPGPAGERGPIGPAGPPGER 496
           G PG RGP G +G  GPPGP GN G+      KG+ G  G PGP G +GP GPAG  G+R
Sbjct: 410 GFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKR 469

Query: 497 GGKGSKGS---QGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553
           G +G  G     GP G RG PG  G  G  G  GP GP G+ G PGP GP G  G  G  
Sbjct: 470 GARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRP 529

Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
           GE G+PG +GL G PG PG  G  GPPGP G  G   P
Sbjct: 530 GEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGP 567



 Score =  158 bits (400), Expect = 2e-38
 Identities = 83/175 (47%), Positives = 92/175 (52%), Gaps = 7/175 (4%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
           QG PG +G  G+RG+ G PGP G++G  G KG  G PG  G RG  GP GPPG  G  G 
Sbjct: 721 QGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGD 780

Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPP------GPPGKEGLPGPQGPPGFQGLQGTVGE 555
           KG  GP G  G  G  G  G  G+PGPP      GPPG +G PG +G PG  G +G  G 
Sbjct: 781 KGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGP 840

Query: 556 PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAV-VPLALQNEPTPAPEDNGCPP 609
           PG  GP G PG  G  G PG KG  G  GP GA   P A      P P  N  PP
Sbjct: 841 PGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPP 895



 Score =  158 bits (399), Expect = 2e-38
 Identities = 78/149 (52%), Positives = 85/149 (57%), Gaps = 3/149 (2%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           G  GP GP G  G  GPPGP G +GQ G  G PGP G AGE G  G  G PG  G  G  
Sbjct: 551 GKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPA 610

Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGL---QGTVGEPGVP 559
           G  G  G++G PG  GP G  G+ GP G PG +GLPGP GPPG  G    QG  G+ G P
Sbjct: 611 GKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAP 670

Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588
           GP G  G  G PG  G +GPPGP GP GA
Sbjct: 671 GPSGARGERGFPGERGVQGPPGPAGPRGA 699



 Score =  156 bits (394), Expect = 8e-38
 Identities = 85/183 (46%), Positives = 96/183 (52%), Gaps = 30/183 (16%)

Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG------------------- 476
           + F    G  GP+GP G+RGS GP GP G+ G+ G  GE G                   
Sbjct: 493 RGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGK 552

Query: 477 --PPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGK 534
             PPGPAG+ G  GP GPPG RG  G  G  GPKG+ G PGK G +G  G PG  GP GK
Sbjct: 553 TGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGK 612

Query: 535 ------EGLPGPQGPPGFQGLQGTVGEP---GVPGPRGLPGLPGVPGMPGPKGPPGPPGP 585
                 +G PGP GP G +G QG  G P   G+PGP G PG  G PG  G  G  G PGP
Sbjct: 613 DGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGP 672

Query: 586 SGA 588
           SGA
Sbjct: 673 SGA 675



 Score =  155 bits (392), Expect = 1e-37
 Identities = 87/201 (43%), Positives = 102/201 (50%), Gaps = 37/201 (18%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKG------------QKGEKGEPGPPGPAGERGPIGP 489
           +GPPGP+G RG  G+ G PG  G++G              G KGEPG PG  G  G +GP
Sbjct: 244 RGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGP 303

Query: 490 AGPPGER---GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF 546
            G PGER   G  G  G++G  G+ G+ G PGP GP+G PG PG  G +G  GPQGP G 
Sbjct: 304 RGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGS 363

Query: 547 QGLQGTVGEPGVPGP---------------------RGLPGLPGVPGMPGPKGPPGPPGP 585
           +G QG  GEPG PGP                      G PG+ G PG PG +GP GP GP
Sbjct: 364 EGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGP 423

Query: 586 SGAVVPLALQNEPTPAPEDNG 606
            G   P     EP  AP   G
Sbjct: 424 GGPPGPKGNSGEP-GAPGSKG 443



 Score =  155 bits (392), Expect = 1e-37
 Identities = 77/152 (50%), Positives = 89/152 (58%), Gaps = 6/152 (3%)

Query: 443 GPPG---PRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGP---AGPPGER 496
           GPPG   P G  G+ G+QGPPGP G  G++GE+G  G PG  G  GP GP   AG PGE+
Sbjct: 602 GPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQ 661

Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
           G  G  G+ GP G+RG  G PG +G  G PGP GP G  G PG  G  G  G  G  G  
Sbjct: 662 GVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQ 721

Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588
           G PG +G+PG  G  G+PGPKG  G  GP GA
Sbjct: 722 GAPGLQGMPGERGAAGLPGPKGDRGDAGPKGA 753



 Score =  154 bits (390), Expect = 2e-37
 Identities = 79/159 (49%), Positives = 91/159 (57%), Gaps = 12/159 (7%)

Query: 442 QGPPGPRGPRGDRGSQGP---------PGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP 492
           QGPPGP GP G+RG QGP         PGP G  G+ G+ GE G PG  G  GP G  G 
Sbjct: 619 QGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGE 678

Query: 493 PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG---L 549
            G  G +G +G  GP G RG+ G PG  G  GD G PG PG +G PG QG PG +G   L
Sbjct: 679 RGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGL 738

Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588
            G  G+ G  GP+G  G PG  G+ G  GP GPPGP+GA
Sbjct: 739 PGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGA 777



 Score =  154 bits (390), Expect = 2e-37
 Identities = 84/176 (47%), Positives = 91/176 (51%), Gaps = 12/176 (6%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG------ERGPIGPAGPPGER 496
           G PGP+G RGD G +G  G  G  G +G  G  GPPGPAG      E GP GPAGP G R
Sbjct: 737 GLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGAR 796

Query: 497 GGKGSKGSQGPKGS---RGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553
           G  G +G  GP G     G PG  G  G  G+PG  G  G  G PGP GP G  G  G V
Sbjct: 797 GAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNV 856

Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609
           G PG  G RG  G PG  G PG  G  GPPGPSG   P      P PA ++ G  P
Sbjct: 857 GAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGP---PGPPGPAGKEGGKGP 909



 Score =  152 bits (384), Expect = 1e-36
 Identities = 85/179 (47%), Positives = 96/179 (53%), Gaps = 30/179 (16%)

Query: 443 GPPGPRGPRG---DRGSQGPPGPTGNK------GQKGEKGEPGPPGPAGERGPIGPAGPP 493
           GP G RG RG   +RG QGPPGP G +      G  G KG+ G PG  G +G  G  G P
Sbjct: 671 GPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMP 730

Query: 494 GERGG------KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP------PGKEGLPGPQ 541
           GERG       KG +G  GPKG+ GSPGK G +G +G  GPPGP       G+ G  GP 
Sbjct: 731 GERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPA 790

Query: 542 GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPP---------GPPGPSGAVVP 591
           GP G +G  G  GEPG PGP G  G PG  G PG KG P         GPPGP+G   P
Sbjct: 791 GPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGP 849



 Score =  151 bits (382), Expect = 2e-36
 Identities = 77/150 (51%), Positives = 84/150 (56%), Gaps = 3/150 (2%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEP---GPPGPAGERGPIGPAGPPGERG 497
           ++G PGP GP G  G  G PG  G  G KG  G P   G PG  G RGP GP GP G  G
Sbjct: 369 VRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPG 428

Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557
            KG+ G  G  GS+G  G  G  GP G  GPPGP G+EG  G +G PG  GL G  GE G
Sbjct: 429 PKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERG 488

Query: 558 VPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
            PG RG PG  GV G  GP G  G PGP+G
Sbjct: 489 GPGSRGFPGADGVAGPKGPAGERGSPGPAG 518



 Score =  147 bits (372), Expect = 3e-35
 Identities = 88/214 (41%), Positives = 96/214 (44%), Gaps = 64/214 (29%)

Query: 439 TILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG------------- 485
           T ++GP G  GPRG RG  GPPG  G  GQ G  G PGPPGP G  G             
Sbjct: 108 TGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGY 167

Query: 486 ------------PIGPAGP---PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPG 530
                       P+GP+GP   PG  G  G +G QGP G  G PG  GP GP G PGPPG
Sbjct: 168 DEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPG 227

Query: 531 ---------------------PPGKEGLPGPQGPP------GFQGLQGTVGEPGVPGPRG 563
                                P G  GLPG  G P      GF GL G  G+ G  GP+G
Sbjct: 228 KNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKG 287

Query: 564 LPGLPGVPGMPGPKGP---------PGPPGPSGA 588
            PG PG  G PG  GP         PG PGP+GA
Sbjct: 288 EPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGA 321



 Score =  146 bits (368), Expect = 8e-35
 Identities = 81/172 (47%), Positives = 88/172 (51%), Gaps = 27/172 (15%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKG------EKGEPGPPGPAGERGP---------- 486
           GP G RG  G  G+ GPPGPTG  G  G       KGE GP GP G  GP          
Sbjct: 317 GPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPP 376

Query: 487 -----IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQ 541
                 GPAG PG  G  G+KG+ G  G  G+PG PG +GPSG  GP GPPG +G  G  
Sbjct: 377 GPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEP 436

Query: 542 GPPGFQGLQGTVGEP------GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           G PG +G  G  GEP      G PGP G  G  G  G PGP G PGPPG  G
Sbjct: 437 GAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERG 488



 Score =  145 bits (367), Expect = 1e-34
 Identities = 84/178 (47%), Positives = 94/178 (52%), Gaps = 13/178 (7%)

Query: 442 QGPPGPRGPRGDR---GSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498
           QG PGP GP G+    G QG PG  G  G  G +GE G PG  G +GP GPAGP   RG 
Sbjct: 643 QGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGP---RGA 699

Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV 558
            G+ G+ G KG  G+PG PG QG  G  G PG  G  GLPGP+G  G  G +G  G PG 
Sbjct: 700 NGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGK 759

Query: 559 PGPRGL------PGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP-TPAPEDNGCPP 609
            G RGL      PG  G PG  G  GP GP GP+GA      + EP  P P     PP
Sbjct: 760 DGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPP 817



 Score =  145 bits (366), Expect = 1e-34
 Identities = 77/168 (45%), Positives = 90/168 (53%), Gaps = 9/168 (5%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            G PG +GP G  G +GPPGP G  G  G  GE G  G  G  G  G  G PG +G +G  
Sbjct: 980  GEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGET 1039

Query: 503  GSQGPKGSRGSPGKPGPQGPSG------DPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
            G  GP G+ G+PG PGP GP+G      + GP GP G  G  G +GP G QG +G  GE 
Sbjct: 1040 GPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGET 1099

Query: 557  GVPGPRGLPGLPGVPGMPGPKGPPGPP---GPSGAVVPLALQNEPTPA 601
            G  G RG+ G  G  G+ GP GPPG P   GPSGA  P   +  P  A
Sbjct: 1100 GEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSA 1147



 Score =  144 bits (363), Expect = 3e-34
 Identities = 84/198 (42%), Positives = 95/198 (47%), Gaps = 35/198 (17%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG--- 498
           Q   G  GP+GD G +GP GP G  G+ G  G+PG PGP    GP GP GPPG  G    
Sbjct: 105 QETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPP---GPPGPPGPPGLGGNFAP 161

Query: 499 ----------------KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQG 542
                            G  G  GP+G  G PG PGPQG  G PG PG PG  G  GP+G
Sbjct: 162 QLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRG 221

Query: 543 PPGFQGLQGTVGE------------PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVV 590
           PPG  G  G  GE            PG  G RGLPG  G+PGM G +G  G  G  G   
Sbjct: 222 PPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAG 281

Query: 591 PLALQNEPTPAPEDNGCP 608
           P   + EP  +P +NG P
Sbjct: 282 PAGPKGEP-GSPGENGAP 298



 Score =  143 bits (360), Expect = 7e-34
 Identities = 86/198 (43%), Positives = 98/198 (49%), Gaps = 38/198 (19%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---------PAGPP 493
           G  GPRG  G+RG  G PGP G +G  G  G  GPPGP G  GP G          AGP 
Sbjct: 299 GQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQ 358

Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGP---QGPSGDPGPPGPPGKE---GLPGPQGPPGFQ 547
           G R      GS+GP+G RG PG PGP    GP+G+PG  G PG +   G PG  G PGF 
Sbjct: 359 GPR------GSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFP 412

Query: 548 GLQGTVGEP---GVPGPRGLPGLPGVPGM---------PGPKGPPGPPGPSGAVVPLALQ 595
           G +G  G     G PGP+G  G PG PG          PGP G  GPPGP+G       +
Sbjct: 413 GARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGAR 472

Query: 596 NEPTPA-----PEDNGCP 608
            EP P      P + G P
Sbjct: 473 GEPGPTGLPGPPGERGGP 490



 Score = 80.9 bits (198), Expect = 4e-15
 Identities = 57/160 (35%), Positives = 62/160 (38%), Gaps = 44/160 (27%)

Query: 472 KGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP 531
           K  PG   P GE  P+ P             GS+ P     +    G +GP GD GP GP
Sbjct: 79  KNCPGAEVPEGECCPVCP------------DGSESPTDQETT----GVEGPKGDTGPRGP 122

Query: 532 PGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPG---------------------- 569
            G      P GPPG  G+ G  G PG PGP G PG PG                      
Sbjct: 123 RG------PAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGIS 176

Query: 570 VPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609
           VPG  GP GP G PGP GA  P   Q  P    E     P
Sbjct: 177 VPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGP 216


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score =  166 bits (419), Expect = 9e-41
 Identities = 81/177 (45%), Positives = 95/177 (53%), Gaps = 21/177 (11%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           G PG  G +G RG +G  GP G  G  G KGE GP GP G  GP+GP G PGERG  G +
Sbjct: 291 GAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQ 350

Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPG---------------------PPGPPGKEGLPGPQ 541
           G+ G +G+ G PGKPGP GP G PG                     P GP G+ G  GP 
Sbjct: 351 GAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPP 410

Query: 542 GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598
           GP G  GL G +G  G PG +G  G PG  G PG  GPPG PGP G+  P  ++ +P
Sbjct: 411 GPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQP 467



 Score =  160 bits (406), Expect = 3e-39
 Identities = 84/172 (48%), Positives = 91/172 (52%), Gaps = 27/172 (15%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            G PG  GP G  G +GPPGP G  G  G  GEPGP GPAG  G  G  G  GERG +G  
Sbjct: 1014 GTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDP 1073

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPG------------PPGPPGKEGLPGPQGP------- 543
            G  G  GS+G+PG PGP G  GD G            PPG  GK GLPGPQGP       
Sbjct: 1074 GPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDH 1133

Query: 544  --------PGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
                     G +G  G  G PG PGP G  G  G+PG  GP+GPPGP GPSG
Sbjct: 1134 GDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSG 1185



 Score =  159 bits (401), Expect = 1e-38
 Identities = 88/182 (48%), Positives = 99/182 (54%), Gaps = 24/182 (13%)

Query: 441  LQGPPGPRGP------RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG 494
            L G PGP GP      +G RG+QGPPG TG  G  G  G   PPGPAG  GP GP G PG
Sbjct: 880  LAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVG---PPGPAGAPGPAGPLGEPG 936

Query: 495  ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPP---GFQGLQG 551
            +   +G  G +G  GS G  G  GP GP G PG  G PG++G PGP GPP   G  G +G
Sbjct: 937  K---EGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRG 993

Query: 552  TVGEPGVPGPRGLPGLPGVPGMP---------GPKGPPGPPGPSGAVVPLALQNEPTPAP 602
             VG PG  G RG+PGLPG  G P         G KGPPGP GP G+  P+       PA 
Sbjct: 994  IVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAG 1053

Query: 603  ED 604
             D
Sbjct: 1054 ND 1055



 Score =  158 bits (399), Expect = 2e-38
 Identities = 85/175 (48%), Positives = 97/175 (55%), Gaps = 18/175 (10%)

Query: 441 LQGPPGP------RGPRGDRGSQGPPGPTG------NKGQKGEKGEPGPPGPAGERGPIG 488
           +QGP GP      RGPRGD G+ GPPGP G      N+G  G  G PGP G  GERGP+G
Sbjct: 490 IQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVG 549

Query: 489 PAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG 548
            +GP G +G  G  G  G  G+RG  G PG QGP G  GP G PG++G PGP G  G +G
Sbjct: 550 SSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRG 609

Query: 549 LQGTVGEPGVPGPRGLPGLP------GVPGMPGPKGPPGPPGPSGAVVPLALQNE 597
             G++G PG  G  G PG P      GVPG  G  G  G  GPSG V P  L  E
Sbjct: 610 QPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGE 664



 Score =  158 bits (399), Expect = 2e-38
 Identities = 88/186 (47%), Positives = 98/186 (52%), Gaps = 24/186 (12%)

Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG---------ERGP 486
           + F    G PGP+G +G+RG  G  GP G++G  G  GEPG PG  G           G 
Sbjct: 527 RGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGK 586

Query: 487 IGPAGPPGE------------RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGK 534
           +GP G PGE            RG  GS G  GPKGS G PGKPG  G +G PG  G PGK
Sbjct: 587 LGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGK 646

Query: 535 EGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGP---PGPSGAVVP 591
           +G  GP GP G  GL G  GE G PGP G  GLPG PG PG  G PG    PG  GAV P
Sbjct: 647 DGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGP 706

Query: 592 LALQNE 597
           L  + E
Sbjct: 707 LGPRGE 712



 Score =  155 bits (393), Expect = 1e-37
 Identities = 81/159 (50%), Positives = 89/159 (55%), Gaps = 12/159 (7%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGPPGERG 497
            L+G PG  G  GDRG  GPPG  G+KG  GE G+PGP   PGPAG  G  G  G PG+RG
Sbjct: 943  LRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRG 1002

Query: 498  GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKE---GLPGPQGP------PGFQG 548
             +G  G  GP G+ G  G  G  G  G PGP GPPG     G PGP+GP      PG  G
Sbjct: 1003 ERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDG 1062

Query: 549  LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
              G  G+ G PGP GLPG  G PG PGP G PG  G  G
Sbjct: 1063 AVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRG 1101



 Score =  155 bits (391), Expect = 2e-37
 Identities = 81/167 (48%), Positives = 90/167 (53%), Gaps = 9/167 (5%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPA------GERGPIGPAGPPG 494
           + G PGP+G RG  G +G  G  GN G +G  G  GPPGPA      GE GP G  GPPG
Sbjct: 769 IAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPG 828

Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGP---SGDPGPPGPPGKEGLPGPQGPPGFQGLQG 551
            RG  GS+G  GP G+ G  G  GP G     G+PG PG  G  G PGPQG  G  G  G
Sbjct: 829 SRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHG 888

Query: 552 TVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598
             G PG+ G RG  G PG  G PG  G  GPPGP+GA  P     EP
Sbjct: 889 PNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEP 935



 Score =  154 bits (390), Expect = 2e-37
 Identities = 82/176 (46%), Positives = 95/176 (53%), Gaps = 10/176 (5%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
           +GP GP+G RG+ G  GP G  G  G  G  G PG  GP G  G  GP G  G  G  G 
Sbjct: 395 RGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGP 454

Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQ------GTVGE 555
           +GS GP+G RG PG PG  G  G+ GP G PG  G+ GP GPPG +G +      GTVG 
Sbjct: 455 QGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGP 514

Query: 556 PGVPGPRGLP---GLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
           PG  G RG P   G PG  G+PGPKG  G  GP G+  P   Q +P   P + G P
Sbjct: 515 PGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDP-GRPGEPGLP 569



 Score =  154 bits (388), Expect = 4e-37
 Identities = 83/177 (46%), Positives = 92/177 (51%), Gaps = 16/177 (9%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG---------PPGPAGERGPIGPAGPP 493
           GPPG  G RG  GS G PGP G+ G  G+ GE G          PG  GE GP GP GPP
Sbjct: 600 GPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPP 659

Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553
           G  G +G +G  GP G +G PG PGP G  G PG  G PG  G  GP GP G +G  G  
Sbjct: 660 GLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGER 719

Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP-------TPAPE 603
           GEPG+ G  G  G+ G  G  GPKG PGP G  G   P  LQ  P       TP P+
Sbjct: 720 GEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPK 776



 Score =  152 bits (385), Expect = 8e-37
 Identities = 75/145 (51%), Positives = 88/145 (60%), Gaps = 3/145 (2%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            G PGP GP G  G+ G  G  G  GQ+GE+G PG PGPAG  G +GP G  G+   KG  
Sbjct: 975  GQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGD---KGPP 1031

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
            G  GP GS G  G+PGP+GP+G+ G PG  G  G  G +G PG  GL G+ G PG PGP 
Sbjct: 1032 GPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPV 1091

Query: 563  GLPGLPGVPGMPGPKGPPGPPGPSG 587
            G PG  G  G PG +GP GPPG +G
Sbjct: 1092 GAPGDAGQRGDPGSRGPIGPPGRAG 1116



 Score =  152 bits (384), Expect = 1e-36
 Identities = 86/210 (40%), Positives = 99/210 (47%), Gaps = 57/210 (27%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGE---KGEPGPPGPAGE---------------- 483
           GPPG +GPRG+RG +G PGP G +G  GE    G+PG PGP G                 
Sbjct: 135 GPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQ 194

Query: 484 -----------------RGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDP 526
                             G +GP GP G +G +G +G  GP G  G PG PGP GP G  
Sbjct: 195 MAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSR 254

Query: 527 GPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGM------------- 573
           GP GPPGK   PG  G PG  G  G VG  G PG RG PG PG+PG+             
Sbjct: 255 GPEGPPGK---PGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPK 311

Query: 574 -----PGPKGPPGPPGPSGAVVPLALQNEP 598
                PG KG  GP GP GA+ PL  +  P
Sbjct: 312 GEVGAPGSKGEAGPTGPMGAMGPLGPRGMP 341



 Score =  152 bits (383), Expect = 1e-36
 Identities = 82/175 (46%), Positives = 94/175 (53%), Gaps = 10/175 (5%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGE---RGPIGPAGPPGERGGK 499
           G PGP GP G RG +GPPG  G  G+ G  G PG  G AG    RG  G  G PG +G +
Sbjct: 243 GDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHR 302

Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPG------PQGPPGFQGLQGTV 553
           G KG +GPKG  G+PG  G  GP+G  G  GP G  G+PG      PQG PG +G  G  
Sbjct: 303 GHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMP 362

Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
           G+PG  GP G+PG  G PG PG KG  GP G  G   P   + E  P P   G P
Sbjct: 363 GKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGP-PGPVGSP 416



 Score =  152 bits (383), Expect = 1e-36
 Identities = 91/213 (42%), Positives = 104/213 (48%), Gaps = 49/213 (23%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTG------------------NKGQKGEKGEPGPPGPAG 482
            L GPPG RG  G RG  GP G  G                    GQKG+ G PGP G AG
Sbjct: 823  LVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAG 882

Query: 483  ERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP---PGKEGLPG 539
              GP GP G PG +GG+G++G  G  G  GS G+ GP GP+G PGP GP   PGKEG PG
Sbjct: 883  SPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPG 942

Query: 540  ---------------PQGPPGFQGLQGTVGEPGVPGPRGLPG---------LPGVPGMPG 575
                           P GPPG  G +G  GE G PGP G PG         + G+PG  G
Sbjct: 943  LRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRG 1002

Query: 576  PKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
             +G PG PGP+G    +     PT A  D G P
Sbjct: 1003 ERGMPGLPGPAGTPGKVG----PTGATGDKGPP 1031



 Score =  151 bits (381), Expect = 2e-36
 Identities = 86/196 (43%), Positives = 105/196 (53%), Gaps = 21/196 (10%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
            +G PGP G  G +G+ G PGP G  G  G++G+PG  GP G  G  G  G PG +G +G 
Sbjct: 1070 RGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGD 1129

Query: 502  KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG---LPGP---QGPPGFQGLQGTVGE 555
            KG  G +G RG  G  G  G  G PGPPGP G++G   +PGP   +GPPG  G  G  G 
Sbjct: 1130 KGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGN 1189

Query: 556  PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP-----LAL--------QNEPTPAP 602
            PG  GP G PG+ G  G  GP+GPPG PGP G   P      AL        ++ P P P
Sbjct: 1190 PGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGDIMGHYDESMPDPLP 1249

Query: 603  E--DNGCPPHWKNFTD 616
            E  ++   P  KN TD
Sbjct: 1250 EFTEDQAAPDDKNKTD 1265



 Score =  150 bits (380), Expect = 3e-36
 Identities = 84/187 (44%), Positives = 94/187 (50%), Gaps = 42/187 (22%)

Query: 443 GPPGPRGPRGD------RGSQGPPGPTGN------------------------------- 465
           GPPGP GP G+      RG  GPPG  GN                               
Sbjct: 804 GPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEP 863

Query: 466 --KGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPS 523
              GQKG+ G PGP G AG  GP GP G PG +GG+G++G  G  G  GS G+ GP GP+
Sbjct: 864 GEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPA 923

Query: 524 GDPGPPGP---PGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPP 580
           G PGP GP   PGKEG PG +G PG  G  G  G  G PG  G  G PG  G PGP GPP
Sbjct: 924 GAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPP 983

Query: 581 GPPGPSG 587
           GP G +G
Sbjct: 984 GPAGTTG 990



 Score =  150 bits (379), Expect = 4e-36
 Identities = 78/160 (48%), Positives = 89/160 (55%), Gaps = 15/160 (9%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKG------QKGEKGEPGPPGPAGERGPIGPAGPPGER 496
           GP GP G  G+RG QGPPGPTG +G        GE G+PG  G  G+ G +GP GP GER
Sbjct: 654 GPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGER 713

Query: 497 GGKGSKGSQGPKG---SRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553
           G  G +G  G  G    +G  G  GP GP G PGP G PG  G PG QG PG +G+ GT 
Sbjct: 714 GNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTP 773

Query: 554 GEPG------VPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           G  G        G  G  G  G  G+PGP GPPGP GP+G
Sbjct: 774 GPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTG 813



 Score =  150 bits (378), Expect = 5e-36
 Identities = 82/174 (47%), Positives = 90/174 (51%), Gaps = 7/174 (4%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
           L GP GP GP G  G +G PGP G  G  G +G PG  G  G  G +G AGP G  G  G
Sbjct: 799 LPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPG 858

Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP---PGKEGLPGPQGPPGFQGLQGTVGEPG 557
            KG  G  G +G  G PGPQG +G PGP GP   PG +G  G QGPPG  G  G+ G  G
Sbjct: 859 VKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVG 918

Query: 558 VPGPRGLPGLPGVPGMPGPKGPP---GPPGPSGAVVPLALQNEPTPAPEDNGCP 608
            PGP G PG  G  G PG +GPP   G PG  G V        P   P D G P
Sbjct: 919 PPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAG-PPGGPGDKGDP 971



 Score =  149 bits (377), Expect = 7e-36
 Identities = 81/174 (46%), Positives = 93/174 (53%), Gaps = 7/174 (4%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           GP G  GP+G RG  G PG  G KG+ G KGEPGP G  G  GP G  G  G RG  G+ 
Sbjct: 453 GPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTV 512

Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
           G  GP G RG+PG  G  G  G PGP G  G+ G  G  GP G QG  G  GEPG+PG R
Sbjct: 513 GPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGAR 572

Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSGAVVP---LALQNEP----TPAPEDNGCPP 609
           GL G PGV G  G  GP G PG  G   P   + ++ +P     P P+ +   P
Sbjct: 573 GLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDP 626



 Score =  148 bits (373), Expect = 2e-35
 Identities = 77/154 (50%), Positives = 86/154 (55%), Gaps = 9/154 (5%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           GP G  G RG  G  G PGP G  G  G  G PG PG  GE GP G  GP G +G +G  
Sbjct: 348 GPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGET 407

Query: 503 GSQGPKGSRGSPGK------PGPQGPSGDPGPPGPPGKEG---LPGPQGPPGFQGLQGTV 553
           G  GP GS G PG       PG +GP+G PG  GPPG  G    PGPQG  G QG++G  
Sbjct: 408 GPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQP 467

Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           G+PGVPG +G  G  G PG  G +GP GPPG  G
Sbjct: 468 GDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEG 501



 Score =  147 bits (371), Expect = 3e-35
 Identities = 83/186 (44%), Positives = 92/186 (49%), Gaps = 29/186 (15%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK--- 499
           G PG RG  G  G  GP GP G  G  GE+GE GPPGP G +G  GP GPPGE GGK   
Sbjct: 636 GVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGE-GGKPGD 694

Query: 500 ----GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGE 555
               G  G+ GP G RG  G PG +G  G  G PG  G  G  GP GP G  G  GT G+
Sbjct: 695 QGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGD 754

Query: 556 PGVPGPRGLPGLPGVPGMPGPKGP---------------------PGPPGPSGAVVPLAL 594
            G PG +G+PG  G+ G PGPKG                      PGP GP G   P   
Sbjct: 755 TGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGE 814

Query: 595 QNEPTP 600
           + EP P
Sbjct: 815 KGEPGP 820



 Score =  147 bits (371), Expect = 3e-35
 Identities = 80/178 (44%), Positives = 90/178 (50%), Gaps = 17/178 (9%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG------------ERGPIGPA 490
            G PGP GP G+ G +GPPG  G+ G  G  G+ GP GP G            + GP GP 
Sbjct: 924  GAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPP 983

Query: 491  GPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQ 550
            GP G  G +G  G  G +G RG PG PGP G  G  GP G  G +G PGP GPPG  G  
Sbjct: 984  GPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNG-- 1041

Query: 551  GTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP--APEDNG 606
              VGEPG  GP G  G PG  G  G +G  G PGP+G          P P  AP D G
Sbjct: 1042 -PVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAG 1098



 Score =  144 bits (364), Expect = 2e-34
 Identities = 78/151 (51%), Positives = 83/151 (54%), Gaps = 9/151 (5%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           G PG RG  G+ G QGP G  G  G  GE G PGPPG  G RG  G  G PG +G  G  
Sbjct: 567 GLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDP 626

Query: 503 GSQGPKGS------RGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
           G  G  G+      RG+PGK G  GPSG  GPPG  G+ G  GP GP GFQGL    G P
Sbjct: 627 GKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLP---GPP 683

Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           G PG  G PG  GVPG PG  GP GP G  G
Sbjct: 684 GPPGEGGKPGDQGVPGDPGAVGPLGPRGERG 714



 Score =  144 bits (362), Expect = 4e-34
 Identities = 81/175 (46%), Positives = 94/175 (53%), Gaps = 30/175 (17%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKG---------EKGEPGPPGPAGERGPIGPAGPP 493
           GP GPRG RG+ G +G PG TG  G+KG          KG PGP G  G+ GP G  G P
Sbjct: 705 GPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMP 764

Query: 494 GERG---------------GKGSKGSQGPKGSRGSPGK---PGPQGPSGDPGPPGPPGKE 535
           GERG                KG++G+ G  G+RG PG    PGP GP+G+ G PGP G  
Sbjct: 765 GERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLV 824

Query: 536 GLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGV---PGMPGPKGPPGPPGPSG 587
           G PG +G PG +G  G  G  G  GP+G  G PGV   PG PG KG  G PGP G
Sbjct: 825 GPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQG 879



 Score =  143 bits (361), Expect = 5e-34
 Identities = 80/166 (48%), Positives = 87/166 (52%), Gaps = 9/166 (5%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG---PPGPAGERGPIGPAGP------ 492
           QGPPGP G +G  G  GPPG  G  G +G  G+PG   P GP GERG  G  G       
Sbjct: 668 QGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGL 727

Query: 493 PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552
           PGE+G  G  G  GPKGS G  G PG  GP G  G PG  G  G PGP+G  G  G +G 
Sbjct: 728 PGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGA 787

Query: 553 VGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598
            G  G  G RGLPG  G PG  GP G  G PGP G V P   +  P
Sbjct: 788 EGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNP 833



 Score =  142 bits (357), Expect = 1e-33
 Identities = 72/151 (47%), Positives = 83/151 (54%), Gaps = 6/151 (3%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           GP GP+G  G  G+ G  GP G +G  GE+G  G PGP G+RG IG  G  G  G  G++
Sbjct: 738 GPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGAR 797

Query: 503 G------SQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
           G        GP G  G  G+PGP+G  G PG  G PG  G  GP G  GF G QG  G+P
Sbjct: 798 GLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQP 857

Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           GV G  G PG  G  G PGP+G  G PGP G
Sbjct: 858 GVKGEPGEPGQKGDAGSPGPQGLAGSPGPHG 888



 Score =  122 bits (306), Expect = 1e-27
 Identities = 88/269 (32%), Positives = 120/269 (44%), Gaps = 30/269 (11%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGER------GPIGPAGPPG 494
            L GP GPRG +GD G +G  G  G++G  G +G PGPPGP GE+      GP GP GPPG
Sbjct: 1120 LPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPG 1179

Query: 495  ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF--QGLQGT 552
              G  G +G+ GP    G  G PG +G  G+ GP GPPG+ G PGP GPPG     L   
Sbjct: 1180 PVGPSGKEGNPGP---LGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGDI 1236

Query: 553  VGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPPHWK 612
            +G      P  LP        P  K     PG    +  L+ Q E   +P+  G   H  
Sbjct: 1237 MGHYDESMPDPLPEFTEDQAAPDDKNKT-DPGVHATLKSLSSQIETMRSPD--GSKKHPA 1293

Query: 613  NFTDKC-----------YYFSVEKEIFEDA-KLFCEDKSSHLVFI---NTREEQQWIKKQ 657
               D             Y+    +   EDA K++C  ++         ++   + W   +
Sbjct: 1294 RTCDDLKLCHSAKQSGEYWIDPNQGSVEDAIKVYCNMETGETCISANPSSVPRKTWWASK 1353

Query: 658  MVGRESHWIGLTDSERENEWKWLDGTSPD 686
                +  W GL D  R +++ + D  SP+
Sbjct: 1354 SPDNKPVWYGL-DMNRGSQFAYGDHQSPN 1381



 Score =  119 bits (299), Expect = 8e-27
 Identities = 73/179 (40%), Positives = 85/179 (47%), Gaps = 39/179 (21%)

Query: 456 SQGPPGPTGN--KGQKGEKGEPG-PPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRG 512
           SQ P G   N  +G+KG+KGEPG  P   G RG  GPAGPPG         SQGP+G RG
Sbjct: 97  SQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPG---------SQGPRGERG 147

Query: 513 SPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG------------------------ 548
             G+PGP+GP G  G PG PG+ G PGP G P   G                        
Sbjct: 148 PKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQ 207

Query: 549 ---LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPED 604
              + G+VG  G  GP+GL G  G  G  GP G PG PGP G +     +  P    ED
Sbjct: 208 VGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGED 266



 Score = 92.4 bits (228), Expect = 1e-18
 Identities = 62/167 (37%), Positives = 71/167 (42%), Gaps = 41/167 (24%)

Query: 477 PPGPAGERGPIGPAGPPGERG--GKGSKGSQGPKGS----RGSPGKPGPQGPSGDPGPPG 530
           P  P GE  P+    P G     G+G KG +G  G      G  G+PGP GP G  GP G
Sbjct: 85  PVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRG 144

Query: 531 PPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPG------------------ 572
             G +G PGP+GP G  G  G  G+PG PGP G P  PG  G                  
Sbjct: 145 ERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGL 204

Query: 573 ------MPGPKGPPGPPGPSGAVVPLALQNE-----PTPAPEDNGCP 608
                 MPG  GP GP GP G      LQ +     PT  P + G P
Sbjct: 205 GSQVGLMPGSVGPVGPRGPQG------LQGQQGGAGPTGPPGEPGDP 245


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score =  165 bits (417), Expect = 2e-40
 Identities = 79/147 (53%), Positives = 90/147 (61%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            G PG  GP G RG  G  G  G +G+KG KGEPGP GP G  GP+G  GPPG  G +G +
Sbjct: 1301 GEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLR 1360

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
            G  GP G  G  G PG  GP G  GP G PG +G  GP+G  G  GL G +G PG  G +
Sbjct: 1361 GIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEK 1420

Query: 563  GLPGLPGVPGMPGPKGPPGPPGPSGAV 589
            G  GLPGV G PGPKG PGPPGP G++
Sbjct: 1421 GDQGLPGVQGPPGPKGDPGPPGPIGSL 1447



 Score =  161 bits (407), Expect = 2e-39
 Identities = 82/155 (52%), Positives = 96/155 (61%), Gaps = 9/155 (5%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGE---KGEPGPPGPAGERGPIGPAGPPGERGG 498
           +G PG  GP+GDRG  G PG  G KGQ+G+    G+PGPPG  GERG  GP GP G+ G 
Sbjct: 538 RGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGE 597

Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPP---GPPGKEGLPGPQGPPGFQGL---QGT 552
            G +G  GP+GS G  G+PG  G  G PG     GPPG+ G PG QG  G QGL   QG 
Sbjct: 598 PGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGL 657

Query: 553 VGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           +G PG  GP G PG+PG+PG  GP G PG  GP+G
Sbjct: 658 IGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTG 692



 Score =  160 bits (404), Expect = 5e-39
 Identities = 86/189 (45%), Positives = 101/189 (53%), Gaps = 23/189 (12%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQ---------------KGEKGEPGPPGPAGERGPI 487
           GP GP+G  G  G +GPPG  G KG+               KG  G PGP GP GE+G  
Sbjct: 761 GPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKS 820

Query: 488 GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF- 546
           G  G PG  G +G  GS+G +G  G+ G+PGP+G  G  G PG PG++GLPG QGPPGF 
Sbjct: 821 GKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFP 880

Query: 547 -----QGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP- 600
                 G QG  G PG PG RG  G  G  G PGP G  GP G +G V PL  +  P P 
Sbjct: 881 GPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPP 940

Query: 601 -APEDNGCP 608
             P + G P
Sbjct: 941 GPPGEQGLP 949



 Score =  157 bits (396), Expect = 4e-38
 Identities = 77/145 (53%), Positives = 84/145 (57%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            G PGPRGP+G  GS+G PG  G  GQ G  GE G  G AG+ GP G  G PG +G  G K
Sbjct: 1172 GAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEK 1231

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
            G  GP G+ G PGK GP G  G  G  GP G  G  GP G PG  G+ G+ GE G PG  
Sbjct: 1232 GDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDV 1291

Query: 563  GLPGLPGVPGMPGPKGPPGPPGPSG 587
            G PG PG  G PG  GPPG  GPSG
Sbjct: 1292 GGPGPPGASGEPGAPGPPGKRGPSG 1316



 Score =  155 bits (393), Expect = 1e-37
 Identities = 86/192 (44%), Positives = 99/192 (51%), Gaps = 36/192 (18%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
           QG PG  GPRG+ G +GP      KGQ G+ GE GPPG AGE+G +G  G PG  G  G 
Sbjct: 748 QGKPGAPGPRGEDGPEGP------KGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGP 801

Query: 502 KGS------QGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGE 555
           KGS       GP G +G  GK G  G  G+ GPPG  G+ G PG  G PG +G  G  G 
Sbjct: 802 KGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGA 861

Query: 556 PGVPGPRGLPGLPGVPGMPGPKGPP------------------------GPPGPSGAVVP 591
           PG+PG +GLPGL G PG PGPKGPP                        GPPGP+G + P
Sbjct: 862 PGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGP 921

Query: 592 LALQNEPTPAPE 603
                E  P  E
Sbjct: 922 QGKTGEVGPLGE 933



 Score =  155 bits (391), Expect = 2e-37
 Identities = 92/197 (46%), Positives = 103/197 (52%), Gaps = 31/197 (15%)

Query: 442  QGPPGP---------RGP---------RGDRGSQGPPGPTGNKGQKGEKGEPGP------ 477
            +GPPGP         RGP          G  GS+GP GP G KG +GE+G PGP      
Sbjct: 997  KGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGI 1056

Query: 478  PGPAGERGPIGPAGPPGERGGKGS------KGSQGPKGSRGSPGKPGPQGPSGDPGPPGP 531
            PGP G  GP G AGP GE G KG       KGS+G KG  G PG+PG +GP+G PGPPG 
Sbjct: 1057 PGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGA 1116

Query: 532  PGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
             G +G  GP G  G +G  G  G  GV GP GL GLPG PG  G  G  G  GP GA  P
Sbjct: 1117 DGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGP 1176

Query: 592  LALQNEPTPAPEDNGCP 608
               Q  PT +    G P
Sbjct: 1177 RGPQG-PTGSEGTPGLP 1192



 Score =  154 bits (390), Expect = 2e-37
 Identities = 84/180 (46%), Positives = 95/180 (52%), Gaps = 33/180 (18%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           G PGP G +G+ GSQG PGP G  G  GEKG PG PG  G  G  GP G PG  G  G K
Sbjct: 635 GEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEK 694

Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQ---GLQGTVGEPGVP 559
           G+QGP GS G PG PGP+G  G  G  G  G++G  G  G PGF+   GL+G  G+PG P
Sbjct: 695 GAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAP 754

Query: 560 GPR------------------------------GLPGLPGVPGMPGPKGPPGPPGPSGAV 589
           GPR                              G+PGLPG PG PGPKG  G PGP G +
Sbjct: 755 GPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPI 814



 Score =  154 bits (390), Expect = 2e-37
 Identities = 81/155 (52%), Positives = 92/155 (59%), Gaps = 9/155 (5%)

Query: 443  GPPGP---RGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG------ERGPIGPAGPP 493
            GPPGP    GP G RG  GP G  G+ G  G KG+ GPPGP G      ERGP+GPAG  
Sbjct: 962  GPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGI 1021

Query: 494  GERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553
            G  G  GS+G  GP G +GS G+ GP GP+G  G PGP G  G PG  GP G +G +G V
Sbjct: 1022 GLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDV 1081

Query: 554  GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588
            G PG  G +G  G  G PG PG +GP G PGP GA
Sbjct: 1082 GAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGA 1116



 Score =  154 bits (389), Expect = 3e-37
 Identities = 97/221 (43%), Positives = 112/221 (50%), Gaps = 44/221 (19%)

Query: 441  LQGPPG---PRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG--------------- 482
            LQGPPG   P+GP G +G  G PG  G +G+ G +G+ GPPGPAG               
Sbjct: 873  LQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLG 932

Query: 483  ERGPIGPAGPPGERGGKGSKGSQGPKGSRGSP---GKPGPQGPSGDPGP---PGPPGKEG 536
            ERGP GP GPPGE+G  G +G +G KG  G P   GK GP G  G PGP   PG PG  G
Sbjct: 933  ERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTG 992

Query: 537  LPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPP---------GPPGPS- 586
            L G +GPPG  G  G+ GE G  GP G  GLPG  G  GP GP          GPPGP+ 
Sbjct: 993  LKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTG 1052

Query: 587  -----GAVVPLALQNEPTPAPE-----DNGCPPHWKNFTDK 617
                 G + PL       P+ E     D G P H  +  DK
Sbjct: 1053 KDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDK 1093



 Score =  153 bits (386), Expect = 6e-37
 Identities = 81/170 (47%), Positives = 88/170 (51%), Gaps = 9/170 (5%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            G  G +G RGD G  GPPG  G  G KG+ GE G  GP+G  GP G  GPPGE G KGS 
Sbjct: 1199 GAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSV 1258

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPGP---------PGPPGKEGLPGPQGPPGFQGLQGTV 553
            G  G  G  G PG PG  G  G PG          PGPPG  G PG  GPPG +G  G +
Sbjct: 1259 GPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHM 1318

Query: 554  GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPE 603
            G  G  G +G  G PG  G PG  GP G  GP G V P  L+  P P  E
Sbjct: 1319 GREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGE 1368



 Score =  151 bits (382), Expect = 2e-36
 Identities = 80/177 (45%), Positives = 97/177 (54%), Gaps = 30/177 (16%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQ---------------KGEKGEPGPPGPAGERGP 486
            +GPPG RG RG  G+ G PGP G+ GQ               +G  G PGP GP G +G 
Sbjct: 832  RGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGK 891

Query: 487  IGPAGPPGERGGKGSKGSQGPK------GSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP 540
             G  G PG+RG  G +G  GP       G +G  G+ GP G  G PGPPGPPG++GLPG 
Sbjct: 892  DGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGL 951

Query: 541  Q---------GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588
            +         GPPG  G +G  G  G PGP+G PG PG  G+ G KGPPGP G +G+
Sbjct: 952  EGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGS 1008



 Score =  150 bits (378), Expect = 5e-36
 Identities = 83/186 (44%), Positives = 97/186 (52%), Gaps = 30/186 (16%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            GPPG  GP G+ G +G  G  G+KG KG+KG+ GPPG  G RGP G  GPPG  G +G +
Sbjct: 1064 GPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRR 1123

Query: 503  GSQG------------------PKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPP 544
            G  G                  P G +G PG PG +G  GD G  GP G  G  GPQGP 
Sbjct: 1124 GPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPT 1183

Query: 545  GFQG---LQGTVGEPGVPGPRGL------PGLPGVPGMPGPK---GPPGPPGPSGAVVPL 592
            G +G   L G VG+PG  G +G       PG PG PG+PGPK   G  G  GPSGA  P 
Sbjct: 1184 GSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPP 1243

Query: 593  ALQNEP 598
              +  P
Sbjct: 1244 GKKGPP 1249



 Score =  149 bits (377), Expect = 7e-36
 Identities = 88/203 (43%), Positives = 99/203 (48%), Gaps = 57/203 (28%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP------PGPAGERGPIGPAGPPGER 496
            GP G  G  G  GS+GP GP G KG +GE+G PGP      PGP G  GP G AGP GE 
Sbjct: 1016 GPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEE 1075

Query: 497  GGKGS------KGSQGPKGSRGSPGKPGPQGPSGDPGPPG-------------------- 530
            G KG       KGS+G KG  G PG+PG +GP+G PGPPG                    
Sbjct: 1076 GDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDD 1135

Query: 531  ----------PPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRG---------LPGLPGVP 571
                      PPG +GLPGP G  G  G  G++G  G PGPRG          PGLPG  
Sbjct: 1136 GVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGV 1195

Query: 572  GMP------GPKGPPGPPGPSGA 588
            G P      G +G  G PGP GA
Sbjct: 1196 GQPGAVGEKGERGDAGDPGPPGA 1218



 Score =  149 bits (376), Expect = 9e-36
 Identities = 87/198 (43%), Positives = 97/198 (48%), Gaps = 32/198 (16%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG------PPGPAGERGPIGPAGPPG 494
           L G PG  GP+G  G  GP GP G KG+ G+ G+PG      PPG  GERG  G  G PG
Sbjct: 792 LPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPG 851

Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPG--------------- 539
            +G  G  G+ G  G +G PG  GP G  G  GPPG  GK+G PG               
Sbjct: 852 PKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTG 911

Query: 540 PQGPPGFQGLQGTVGE---------PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVV 590
           P GP G  G QG  GE         PG PGP G  GLPG+ G  G KG  GPPGP G   
Sbjct: 912 PPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEG 971

Query: 591 PLALQNEPTP--APEDNG 606
           P  L+  P P   P D G
Sbjct: 972 PAGLRGFPGPKGGPGDPG 989



 Score =  147 bits (372), Expect = 3e-35
 Identities = 80/184 (43%), Positives = 95/184 (51%), Gaps = 15/184 (8%)

Query: 435  IKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG 494
            ++ F   +G PG  GP G +G +GPPGP G  G  GE+G  GP G  G  G  G  GP G
Sbjct: 975  LRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVG 1034

Query: 495  ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQ---- 550
              G KGS+G +GP G  G  G PGP GP G PG  GP G+EG  G  G PG +G +    
Sbjct: 1035 PAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKG 1094

Query: 551  --GTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPS---------GAVVPLALQNEPT 599
              G  G+PG+ GP G PG PG  G  G +GPPG  G           G + P  LQ  P 
Sbjct: 1095 DAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPG 1154

Query: 600  PAPE 603
            P  E
Sbjct: 1155 PPGE 1158



 Score =  147 bits (370), Expect = 5e-35
 Identities = 83/186 (44%), Positives = 94/186 (50%), Gaps = 25/186 (13%)

Query: 442  QGPPGPRGPRGDRGS------------QGPPGPTGNKGQKGEKGEPGP---PGPAGERGP 486
            +GPPG  G +GD G             QG PGP G KG+ G+ G  GP   PGP G +GP
Sbjct: 1123 RGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGP 1182

Query: 487  IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGP---------PGPPGKEGL 537
             G  G PG  GG G  G+ G KG RG  G PGP G  G PGP          GP G  G 
Sbjct: 1183 TGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGP 1242

Query: 538  PGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNE 597
            PG +GPPG  G +G+VG  G+PG  G PG PGV G+ G  G  G PG  G   P     E
Sbjct: 1243 PGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGE 1302

Query: 598  P-TPAP 602
            P  P P
Sbjct: 1303 PGAPGP 1308



 Score =  146 bits (369), Expect = 6e-35
 Identities = 79/168 (47%), Positives = 89/168 (52%), Gaps = 12/168 (7%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           G PGP G  G+RG++GPPGPT      G+ GEPGP G  G RG  GP G PG  G  G+ 
Sbjct: 572 GQPGPPGEDGERGAEGPPGPT------GQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAP 625

Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGL------QGTVGEP 556
           G++G  G  G PG PG QG  G  G PGP G  G PG +GPPG  G+       G +G P
Sbjct: 626 GAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHP 685

Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPED 604
           G  GP G  G  G PG  GP G PGP G  G      LQ E     ED
Sbjct: 686 GHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGED 733



 Score =  144 bits (364), Expect = 2e-34
 Identities = 77/158 (48%), Positives = 87/158 (55%), Gaps = 12/158 (7%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
            +G  GP G  G  G +GPPG  G KG  G  G PG  GP G+ G  G  G PGE+G  G 
Sbjct: 1231 KGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGD 1290

Query: 502  KGSQGPKGSRGSPGKPGP---QGPSGDPGPPGPPGKEGL---PGPQGPPGFQGLQGTVGE 555
             G  GP G+ G PG PGP   +GPSG  G  G  G++G    PGP GPPG  G  G  G 
Sbjct: 1291 VGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGP 1350

Query: 556  PGVPGPRGLPGL------PGVPGMPGPKGPPGPPGPSG 587
            PG  GP GL G+      PG+ G PG  GPPGP GPSG
Sbjct: 1351 PGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSG 1388



 Score =  144 bits (362), Expect = 4e-34
 Identities = 75/163 (46%), Positives = 88/163 (53%), Gaps = 3/163 (1%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
           + G PG  GP G  G +GP G  G +G  G  G PG PGP G +G  G  G  GE+G KG
Sbjct: 672 IPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKG 731

Query: 501 SKGSQGPKGS---RGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557
             G  G KG    +G  GKPG  GP G+ GP GP G+ G  G +GPPG  G +G +G PG
Sbjct: 732 EDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPG 791

Query: 558 VPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP 600
           +PG  G PG  G  G PGP GP G  G SG      L+ E  P
Sbjct: 792 LPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGP 834



 Score =  140 bits (354), Expect = 3e-33
 Identities = 84/191 (43%), Positives = 98/191 (51%), Gaps = 23/191 (12%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP---IGPAGPPGERG 497
           ++GPPGP G  G  G  G PG  G KG++G +G  GP G  G  GP   +G  G PG  G
Sbjct: 477 MKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADG 536

Query: 498 GKGSKGSQGPKGSRGS---PGKPGPQGPSGD------PGPPGPPGK---EGLPGPQGPPG 545
            +G  G  GPKG RG    PG PG +G  GD      PGPPG  G+   EG PGP G  G
Sbjct: 537 ARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAG 596

Query: 546 FQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKG---PPGPPGPSGAVVPLALQNEPTP-- 600
             G +G +G  G PGP G PG+ G+ G PG KG   PPG PGP G       Q  P P  
Sbjct: 597 EPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQG 656

Query: 601 ---APEDNGCP 608
               P + G P
Sbjct: 657 LIGTPGEKGPP 667



 Score =  139 bits (350), Expect = 9e-33
 Identities = 85/198 (42%), Positives = 95/198 (47%), Gaps = 36/198 (18%)

Query: 442 QGPPGPRG------PRGDRGSQGPPGPTGN------------KGQKGEKGEPGPPGPAGE 483
           +GPPGP G      PRG  G +G PGPTG             KG  G  GEPGPPG  G 
Sbjct: 586 EGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGN 645

Query: 484 R------GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL 537
                  GP G  G PGE+G  G+ G  G  GS G  G PG +GP+G+ G  GPPG  G 
Sbjct: 646 HGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGP 705

Query: 538 PGPQGPPGF------QGLQGTVGE------PGVPGPRGLPGLPGVPGMPGPKGPPGPPGP 585
           PG  GP G       +GLQG  GE      PG  G  GL G  G PG PGP+G  GP GP
Sbjct: 706 PGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGP 765

Query: 586 SGAVVPLALQNEPTPAPE 603
            G       +  P  A E
Sbjct: 766 KGQAGQAGEEGPPGSAGE 783



 Score =  134 bits (337), Expect = 3e-31
 Identities = 74/162 (45%), Positives = 81/162 (50%), Gaps = 18/162 (11%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
            + GP G  G  G  G  GPPGP G  G  G KG+ GP G  G  G IG  GPPGE     
Sbjct: 1362 IPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEA---- 1417

Query: 501  SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPG 560
                 G KG +G PG  GP GP GDPGPPGP G  G PGP G  G  G +G+ G PG  G
Sbjct: 1418 -----GEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMG 1472

Query: 561  PRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAP 602
            PR         G  GP GPPGPPG    +  L  +    P P
Sbjct: 1473 PR---------GDTGPAGPPGPPGAPAELHGLRRRRRFVPVP 1505



 Score =  128 bits (321), Expect = 2e-29
 Identities = 78/190 (41%), Positives = 85/190 (44%), Gaps = 45/190 (23%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGE----------------------KGEP----- 475
           GP GP GP G  G  GPPGP G  G  G                       KG P     
Sbjct: 404 GPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQ 463

Query: 476 ---------------GPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQ 520
                          GPPGP G  G  GP G PG  G KG +G++GP+G RG  G  GP 
Sbjct: 464 AQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPP 523

Query: 521 GPSGDPGPPGPPGKEGLPG---PQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPK 577
           G  G  G PG  G  GLPG   P+G  GF GL G  GE G  G  G  G PG PG  G +
Sbjct: 524 GRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGER 583

Query: 578 GPPGPPGPSG 587
           G  GPPGP+G
Sbjct: 584 GAEGPPGPTG 593



 Score =  112 bits (281), Expect = 1e-24
 Identities = 82/216 (37%), Positives = 96/216 (44%), Gaps = 50/216 (23%)

Query: 438 FTILQGPPGPRGPRGD-----RGSQ--GPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPA 490
           F I  G  G +G +G+     +G Q  GPPG  G +G  G  G PGPPG  G+ GP GPA
Sbjct: 366 FQIFPGA-GEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPA 424

Query: 491 GPPGERGGKGSKGSQG---------PKGS-RGSP--------------------GKPGPQ 520
           G PG  G  G +G  G           GS +G P                    G PGP 
Sbjct: 425 GLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPV 484

Query: 521 GPSGDPGP---PGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPK 577
           G +G PGP   PG PG +G  G +GP G +GLQG  G PG  G  G PG  G  G+PG  
Sbjct: 485 GLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDT 544

Query: 578 GP---------PGPPGPSGAVVPLALQNEPTPAPED 604
           GP         PG PG  G         +P P  ED
Sbjct: 545 GPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGED 580



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 23/60 (38%), Positives = 25/60 (41%), Gaps = 9/60 (15%)

Query: 556 PGVPGPRGLPGLPGV-------PGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
           PG  G +G  G P V        G PG  GP G  GPSG   P     +P P P   G P
Sbjct: 370 PGA-GEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGP-PGPAGLP 427


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  162 bits (410), Expect = 1e-39
 Identities = 88/173 (50%), Positives = 97/173 (56%), Gaps = 26/173 (15%)

Query: 442  QGPPGPRGP---RGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAG---- 491
            QGP G RG    +GDRG  GP G  GN G  GE+G  GP   PG  G RGP GP G    
Sbjct: 2125 QGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGD 2184

Query: 492  --PPGERGGKGSKGSQGPKGSRGSPGKPGP-----QGPSGDPGPPGPPGKEGLPGPQGPP 544
              PPG  G  G  G QGP G +G PG+ GP      GP+G  G PGPPG  GL GPQG P
Sbjct: 2185 PGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSP 2244

Query: 545  GFQGLQGTVGEPGVP---------GPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588
            G  G  G  G+PG P         G RG PG+PG PG+PGP GP G PGP+GA
Sbjct: 2245 GLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGA 2297



 Score =  154 bits (389), Expect = 3e-37
 Identities = 91/201 (45%), Positives = 104/201 (51%), Gaps = 42/201 (20%)

Query: 442  QGPPGPRGP------------RGDRGSQGPPG-------PTGNKGQKGEKGEPGPPGPAG 482
            QGPPG  GP            RGD G QGPPG       P G  G  GE G+PG PG  G
Sbjct: 1987 QGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPG 2046

Query: 483  ERGPIGPAGPPGERGGKGSKGSQG------PKGSRGSPGKPGPQGP-----------SGD 525
              G +G AG PGERG +G KG +G      P G  G+PG PGP GP           SG+
Sbjct: 2047 RAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGE 2106

Query: 526  PGPPGPPGKEGLPGP---QGPPGFQGLQGTVGEPGVPGPRGL---PGLPGVPGMPGPKGP 579
             GPPG  G +G PG    QGP G +G+ G  G+ G PGPRG    PGLPG  GM GP+G 
Sbjct: 2107 QGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGK 2166

Query: 580  PGPPGPSGAVVPLALQNEPTP 600
            PG  GP G   P+    +P P
Sbjct: 2167 PGLQGPRGPPGPVGGHGDPGP 2187



 Score =  154 bits (388), Expect = 4e-37
 Identities = 95/223 (42%), Positives = 105/223 (47%), Gaps = 60/223 (26%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGN--KGQKGEKGEPGPPGPA---------------GERG 485
            GPPGPRGP GD G +GPPG  G   KG KG++GE GPPGP                G  G
Sbjct: 1374 GPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPG 1433

Query: 486  PIGPAGPPGERGGKGSK-----------------------GSQGPKGSRGSPGKPGPQGP 522
            P GP GPPG++G KG                         G+ GPKG RG PG  G  G 
Sbjct: 1434 PQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGE 1493

Query: 523  SGDPGPPGPPGKEGLPG---------PQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGM 573
             G+ GPPGP G  GLPG         P+GPPG  G QG  GEPG PG   + G P V G 
Sbjct: 1494 KGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVG-PAVAGP 1552

Query: 574  PGPKGPPGPPGPSGAV--------VPLALQNEPTPA--PEDNG 606
             G KG  GP GP GA           L L  +P P   P D G
Sbjct: 1553 KGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRG 1595



 Score =  154 bits (388), Expect = 4e-37
 Identities = 82/169 (48%), Positives = 90/169 (53%), Gaps = 7/169 (4%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKG----EKGEPGPPGPAGERGPIGPAGPPGERGG 498
            G PG  GP+GDRG  GPPGP G     G    EKGEPG  G  G RGP G  G PG  G 
Sbjct: 1685 GSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGE 1744

Query: 499  KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV 558
            +G +G +GP G +G PG  GP G  GD GPPG  G+ GL G  G  G  G  G  G+ G 
Sbjct: 1745 RGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGD 1804

Query: 559  PGPRGLPGLPGVPGMPGPKGP---PGPPGPSGAVVPLALQNEPTPAPED 604
            PG  GLPGL G  G+PGP GP   PG PG  G         EP    ED
Sbjct: 1805 PGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGED 1853



 Score =  154 bits (388), Expect = 4e-37
 Identities = 81/169 (47%), Positives = 96/169 (56%), Gaps = 17/169 (10%)

Query: 446  GPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQ 505
            GPRG +G+RG +G  G  G KG KGE G PG PG AG +G +G  G PG+ G  G +G  
Sbjct: 2620 GPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLI 2679

Query: 506  GPKGSRGSPGKPGPQGPSGDPGP---------PGPPGKEGLPGPQGPPGF------QGLQ 550
            GPKG RG  G+PGP+G  G+ G          PGP G +G  GP GPPG       +GLQ
Sbjct: 2680 GPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQ 2739

Query: 551  GTVGEPGVPGPR--GLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNE 597
            G  GE G PG R  G PG+PG PG  G +G PGP GP G     AL  +
Sbjct: 2740 GQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTED 2788



 Score =  152 bits (385), Expect = 8e-37
 Identities = 82/179 (45%), Positives = 97/179 (54%), Gaps = 31/179 (17%)

Query: 440  ILQGPPGPRGPRGDRGS------QGPPGPTGNKGQKGEKGEPGPPGP---------AGER 484
            +L G PGP+G  GDRG        GPPG +G  G+KG+ G PGPPGP          GE+
Sbjct: 1580 VLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEK 1639

Query: 485  GPIGPAGPP------GERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLP 538
            G  GP G P      GERG +G+ G +GP G +G  G PG  G +G PG  GP G  G P
Sbjct: 1640 GDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEP 1699

Query: 539  GPQGPPG----------FQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
            GP GPPG           +G  G  G+ G  GP+G PGLPG PG  G +G  GPPGP G
Sbjct: 1700 GPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQG 1758



 Score =  151 bits (381), Expect = 2e-36
 Identities = 93/229 (40%), Positives = 107/229 (46%), Gaps = 64/229 (27%)

Query: 442  QGPPGPRGPRG---------DRGSQGPPGPTGNKGQKGEKGEPGPP--------GPAGER 484
            +GPPGP G RG          +G +GPPGPTG +G+KGE G PG P        GP GE+
Sbjct: 1497 RGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEK 1556

Query: 485  GPIGPAGP-----------------PGERGGKGSKGSQGP---KGSRGSPGKPGPQGPSG 524
            G +GPAGP                 PG+ G KG  G +GP    G  G PG  GP G  G
Sbjct: 1557 GDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKG 1616

Query: 525  DPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGP---RGLPGLPGV----------- 570
            DPG PGPPG  G  G  G  G +G +G  G+PG+PG    RGL G PGV           
Sbjct: 1617 DPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQG 1676

Query: 571  ----------PGMPGPKGP---PGPPGPSGAVVPLALQNEPTPAPEDNG 606
                      PG  GPKG    PGPPGP G +V           P D G
Sbjct: 1677 DPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRG 1725



 Score =  149 bits (376), Expect = 9e-36
 Identities = 83/172 (48%), Positives = 96/172 (55%), Gaps = 22/172 (12%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
            +GPPG  GP+GDRG    PGP G  G+KGE+   GPPGPAG RG  G AG PG +G +G 
Sbjct: 1470 RGPPGAIGPKGDRGF---PGPLGEAGEKGER---GPPGPAGSRGLPGVAGRPGAKGPEGP 1523

Query: 502  KGSQGPKGSRGSPGKP-----------GPQGPSGDPGPPGPPGKEGLPGPQGPPG--FQG 548
             G  G +G +G PG+P           GP+G  GD GP GP G  G+ G +GPPG    G
Sbjct: 1524 PGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPG 1583

Query: 549  LQGTVGEPGVPGPRGLPGLPGVP---GMPGPKGPPGPPGPSGAVVPLALQNE 597
              G  G+PG  GP GL G  G P   G PG KG PG PGP G V P     E
Sbjct: 1584 DPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGE 1635



 Score =  149 bits (376), Expect = 9e-36
 Identities = 81/170 (47%), Positives = 94/170 (55%), Gaps = 14/170 (8%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG-----ERG 497
            G PG  G  G  G  G PG  G +G+KGE+GE G  GP G  G  GP GPPG     +  
Sbjct: 2040 GIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEP 2099

Query: 498  GKGSKGSQGP---KGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGP------PGFQG 548
            G G  G QGP   KG++G PG  G QGP GD G PG  G  G PGP+G       PG +G
Sbjct: 2100 GPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERG 2159

Query: 549  LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598
            + G  G+PG+ GPRG PG  G  G PGP G PG  GP+G   P  L+ EP
Sbjct: 2160 MAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEP 2209



 Score =  149 bits (375), Expect = 1e-35
 Identities = 79/160 (49%), Positives = 88/160 (55%), Gaps = 14/160 (8%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
            QGPPG    +G+RG  G  G  G+ G+ G  G PG PG  G  G  GP G PGERG +G 
Sbjct: 1286 QGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGP 1345

Query: 502  KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL---PGPQGPPGFQGL-----QGTV 553
            KG  G  G       PG  G  GDPGP GPPG  G    PGP+GPPG  G      +G  
Sbjct: 1346 KGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDR 1405

Query: 554  GEPGVPGP------RGLPGLPGVPGMPGPKGPPGPPGPSG 587
            GE G PGP       G PGLPG+PG PGP+GP GPPG  G
Sbjct: 1406 GERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKG 1445



 Score =  148 bits (373), Expect = 2e-35
 Identities = 83/170 (48%), Positives = 90/170 (52%), Gaps = 21/170 (12%)

Query: 443  GPPGPRGPRGDRGSQGPPGPT--GNKGQKGEKGEPGP-----------------PGPAGE 483
            G PGP GP+G+ G  G PG    G  G KGEKG PG                  PGP GE
Sbjct: 2281 GLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGE 2340

Query: 484  RGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGK--PGPQGPSGDPGPPGPPGKEGLPGPQ 541
            +G  G AG PG+ G  G KG+ GPKG +G PG   PG  GP G PG  G  G  GLPG  
Sbjct: 2341 KGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAP 2400

Query: 542  GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
            G  GF G  G  GE G PGP G  GL G PG  G  GP GPPGP G+V P
Sbjct: 2401 GVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGP 2450



 Score =  142 bits (359), Expect = 9e-34
 Identities = 80/174 (45%), Positives = 96/174 (55%), Gaps = 31/174 (17%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGE-----RGPIGPAGPPGER 496
            +G PGPRG +G+ G  G PG   + G+ G+KG PGP G  G+      G  GP GPPG +
Sbjct: 2332 RGLPGPRGEKGEAGRAGEPG---DPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVK 2388

Query: 497  GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGP------PGPPGKEGLPGP---------Q 541
            G  G  G  G  G  G PG+ GP+G  G PGP       GPPG+EG+PGP          
Sbjct: 2389 GDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSV 2448

Query: 542  GPPGFQGLQGTVGEPGV--PGPRGLPGLPGV------PGMPGPKGPPGPPGPSG 587
            GPPG  GL+G  G+PGV  PGPRG  G PG+      PG  GP+G  GPPG  G
Sbjct: 2449 GPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRG 2502



 Score =  140 bits (354), Expect = 3e-33
 Identities = 82/209 (39%), Positives = 99/209 (47%), Gaps = 57/209 (27%)

Query: 440  ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGE------------RGPI 487
            ++ GPPGPRG +GD G +GP G  G+KG +G+ G+PG  G  GE            RG +
Sbjct: 2524 VILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLL 2583

Query: 488  GPAGPPG------------------------------------ERGGKGS---KGSQGPK 508
            GP G PG                                    ERG KG+    G +G K
Sbjct: 2584 GPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDK 2643

Query: 509  GSRGSPGKPGPQGPSGD------PGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
            G  G PG+PG  G  G+      PG  G PGKEGL GP+G  GF G  G  G+ G  G R
Sbjct: 2644 GEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGER 2703

Query: 563  GLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
            G PG+ G PG  G  G  GPPGP G+V P
Sbjct: 2704 GTPGIGGFPGPSGNDGSAGPPGPPGSVGP 2732



 Score =  139 bits (351), Expect = 7e-33
 Identities = 77/179 (43%), Positives = 92/179 (51%), Gaps = 33/179 (18%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
            +G PG RG  G RG +G PG  G  G++G +G  GPPGP G+ G  GPAG  G+RG  G 
Sbjct: 1718 KGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGL 1777

Query: 502  KGSQGPKGSRGSPGKPGPQ---GPSGDPGPPGPP---GKEGLPGPQGPPGFQGLQGTVGE 555
             G  G  G  G+ G  GP    G +GDPG  G P   G++GLPGP GPPG  G  G  G+
Sbjct: 1778 DGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGK 1837

Query: 556  PGVPGPRGLPGLP---------------------------GVPGMPGPKGPPGPPGPSG 587
            PG+ G  G PG P                           G PG+ GP+GPPG PGP G
Sbjct: 1838 PGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVG 1896



 Score =  139 bits (350), Expect = 9e-33
 Identities = 86/188 (45%), Positives = 91/188 (48%), Gaps = 24/188 (12%)

Query: 441  LQGPPGPRGPRGDRGSQGPPG---------PTGNKGQKGEKGEPGPPG-----PAGERGP 486
            LQGP GP GP G  G  GPPG         P G  G KGE GE GPPG     P G  G 
Sbjct: 2169 LQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGL 2228

Query: 487  IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSG---DPGPPGPPGKEGLPGPQGP 543
             GP GP G  G +GS G  G  G  G PG PG  G SG   D G PG PG  GLPGP GP
Sbjct: 2229 PGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGP 2288

Query: 544  PGFQGLQGTVGEP--GVPGPRGLPGLPG-----VPGMPGPKGPPGPPGPSGAVVPLALQN 596
             G  G  G  G+   G+PG +G  G PG     + G PG KG  G PGP G         
Sbjct: 2289 KGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAG 2348

Query: 597  EPTPAPED 604
            EP    ED
Sbjct: 2349 EPGDPGED 2356



 Score =  136 bits (342), Expect = 8e-32
 Identities = 80/184 (43%), Positives = 93/184 (50%), Gaps = 20/184 (10%)

Query: 441  LQGPPGPRGPRGDRGSQGPPG-------------PTGNKGQKGEKGEPGPPGPAGERGPI 487
            L GPPG RG RG++G  G  G             P G +G KG+ GE GP G  G++GP 
Sbjct: 2494 LTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPR 2553

Query: 488  GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQ 547
            G  G PG+   KGSKG  G KGS G PG  G  GP G PG  G PG  G PG  G PG +
Sbjct: 2554 GDNGDPGD---KGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIR 2610

Query: 548  GLQGTV---GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPED 604
            G +G V   G  G+ G RG+ G  G+ G  G KG  GPPG  G         EP   P  
Sbjct: 2611 GEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEP-GVPGQ 2669

Query: 605  NGCP 608
            +G P
Sbjct: 2670 SGAP 2673



 Score =  135 bits (341), Expect = 1e-31
 Identities = 77/184 (41%), Positives = 92/184 (50%), Gaps = 23/184 (12%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG--- 498
            QG PG  G  G+ G  G PG  G  G+ G++G PG PG  G  GP+GP G PG  G    
Sbjct: 2241 QGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQ 2300

Query: 499  --------KGSKGSQG-----------PKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPG 539
                    KG KG+ G            KG RG PG  G +G +G  G PG PG++G  G
Sbjct: 2301 AVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKG 2360

Query: 540  PQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPT 599
              GP GF+G  G VG PG PGP G PG+ G  G+PG  G PG  G  G   P     +P 
Sbjct: 2361 APGPKGFKGDPG-VGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPG 2419

Query: 600  PAPE 603
            P+ E
Sbjct: 2420 PSGE 2423



 Score =  135 bits (339), Expect = 2e-31
 Identities = 73/154 (47%), Positives = 86/154 (55%), Gaps = 8/154 (5%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGP---AGERGPIGPAGPPGERGG 498
            QG PG RGP G++G +GPPG  G  G  G+ G  GP GP   AG+ G  G  G PG RG 
Sbjct: 1757 QGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGE 1816

Query: 499  KGSKGSQGPKGSRGSPG---KPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGE 555
            +G  G  GP G  G PG   KPG  G +G+PG PG  G++G  G  G  G +G  G  GE
Sbjct: 1817 QGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGE 1876

Query: 556  PGVPGPRGLPGLPGVPGMPGPKGP--PGPPGPSG 587
             G PG  G  G PG+PG  GP G   PG PG +G
Sbjct: 1877 RGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTG 1910



 Score =  134 bits (336), Expect = 4e-31
 Identities = 85/220 (38%), Positives = 101/220 (45%), Gaps = 49/220 (22%)

Query: 436  KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKG---------------------- 473
            + F  + G  GP+G RG+ GS+G  G  G +G +GE G                      
Sbjct: 1900 QGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREI 1959

Query: 474  -----------------EPGPPGPAGERGPIGPAGP---PGERGGKGSKGSQGPKGSRG- 512
                               GP G +GE+GP G  GP   PGERG KG +G  GP+G  G 
Sbjct: 1960 VETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGL 2019

Query: 513  SPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPG 572
            + G+ GP GPSG  G PG PG  GLPG  G  G  G  G  GE G  G RG  G  G PG
Sbjct: 2020 ALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPG 2079

Query: 573  MPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPPHWK 612
            +PG  GPPGPPGP  +V      +EP P       PP  K
Sbjct: 2080 LPGTPGPPGPPGPKVSV------DEPGPGLSGEQGPPGLK 2113



 Score =  134 bits (336), Expect = 4e-31
 Identities = 83/177 (46%), Positives = 92/177 (51%), Gaps = 30/177 (16%)

Query: 441  LQGPPGPRGPRGDRGSQGPP---GPTGNKGQKGEKGEPGP--PGPAGER----------- 484
            L GPPG  G  G  G  GPP   GP G  G KG+KG+PG   PGP GER           
Sbjct: 2426 LAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGR 2485

Query: 485  ----GPIGPAGPP---GERGGKGSKGSQGPKGSRGSP----GKPGPQGPSGDPGPPGPPG 533
                GP G  GPP   GERG KG  GS G KG +G      G PGP+G  GD G  GP G
Sbjct: 2486 PGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRG 2545

Query: 534  KEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGV---PGMPGPKGPPGPPGPSG 587
             +G  GP+G  G  G +G+ GEPG  G  GLPGL G+    G PG  G PG PG  G
Sbjct: 2546 LDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPG 2602



 Score =  133 bits (334), Expect = 7e-31
 Identities = 73/153 (47%), Positives = 87/153 (56%), Gaps = 10/153 (6%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPA----GPPGERG 497
            +G PG RG  G  G +GP G TG  G +GE+GE G  G AG +G  G +    GPPG RG
Sbjct: 2474 RGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRG 2533

Query: 498  GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP- 556
             KG  G +GP   RG  G  GP+G +GDPG  G  G+ G  G  G PG +GL G  G+P 
Sbjct: 2534 AKGDMGERGP---RGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPG 2590

Query: 557  --GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
              G+PG  G PG  GVPG+ G KG  G  GP G
Sbjct: 2591 AAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRG 2623



 Score =  132 bits (331), Expect = 2e-30
 Identities = 70/138 (50%), Positives = 79/138 (57%), Gaps = 11/138 (7%)

Query: 454  RGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGS 513
            +G +G PG  G +GQ G  G+PG PG  G  GP    GPPG    KG +G  G   + G 
Sbjct: 1253 KGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGP---QGPPGSATAKGERGFPG---ADGR 1306

Query: 514  PGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGP----RGLPGLPG 569
            PG PG  G  G PG PG  G  GLPGP+G PG +G +G  GEPG PG      G PGLPG
Sbjct: 1307 PGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEG-PGLPG 1365

Query: 570  VPGMPGPKGPPGPPGPSG 587
              G PGP GPPGP GP G
Sbjct: 1366 RKGDPGPSGPPGPRGPLG 1383



 Score =  127 bits (320), Expect = 3e-29
 Identities = 80/185 (43%), Positives = 94/185 (50%), Gaps = 24/185 (12%)

Query: 443  GPPGPRGPRGDRGSQG---PPGPTGNKGQKGEKGEPGPPGPAGERG------------PI 487
            GPPGP G +GD G  G    PG  G  GQ G +GE G PGP+GERG            P+
Sbjct: 2380 GPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPL 2439

Query: 488  GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQ 547
            GP GPPG  G  G+ G +G KG  G  G PGP+G  G+PG  G  G+ G  GP+G  G  
Sbjct: 2440 GPPGPPGSVGPPGASGLKGDKGDPG-VGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPP 2498

Query: 548  GLQGTVGEPGVPGPRGLPGLPG----VPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPE 603
            G +G  GE G  G  GL G  G    + G PGP+G  G  G  G   P  L  +  P   
Sbjct: 2499 GSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERG---PRGLDGDKGPR-G 2554

Query: 604  DNGCP 608
            DNG P
Sbjct: 2555 DNGDP 2559



 Score =  127 bits (318), Expect = 5e-29
 Identities = 83/219 (37%), Positives = 94/219 (42%), Gaps = 62/219 (28%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGE---------------RG 485
            L G PG  GP G  G+ G  G  G  G  G +GE G PGP+G                 G
Sbjct: 1783 LDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNG 1842

Query: 486  PIGPAGPPGERGGKGSKGS---------QGPKGSRGSPGKPGPQGPSGDPGPPGPPGK-- 534
              G  G PGE G KG KG           GPKG RG+PG  GPQGP G PGP GPPG+  
Sbjct: 1843 KNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGF 1902

Query: 535  EGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPG-VPGMP------------------- 574
             G+PG  GP G +G  G+ GE G+PG RGL G PG VP +                    
Sbjct: 1903 PGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVET 1962

Query: 575  ----------------GPKGPPGPPGPSGAVVPLALQNE 597
                            GPKG  G  GP G   P+    E
Sbjct: 1963 WDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGE 2001



 Score =  102 bits (255), Expect = 1e-21
 Identities = 49/100 (49%), Positives = 54/100 (54%)

Query: 489  PAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG 548
            P G  GE G  G +G  GP G  G PG+ G  GP G PG     G+ G PG  G PG  G
Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPG 1311

Query: 549  LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588
              G  G PG PG +G PGLPG  G PG +GP GP G  GA
Sbjct: 1312 RAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGA 1351



 Score = 98.6 bits (244), Expect = 2e-20
 Identities = 48/98 (48%), Positives = 55/98 (56%), Gaps = 6/98 (6%)

Query: 507  PKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF------QGLQGTVGEPGVPG 560
            PKG +G PG+ G +G  G PG PG PG+ G PGPQGPPG       +G  G  G PG PG
Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPG 1311

Query: 561  PRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598
              G PG PG PG+ G  G PGP G  G   P   + EP
Sbjct: 1312 RAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEP 1349



 Score = 33.1 bits (74), Expect = 0.96
 Identities = 17/41 (41%), Positives = 19/41 (46%)

Query: 561  PRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601
            P+G  G PG  G+ G  GPPG PG  G       Q  P  A
Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSA 1292


>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
          Length = 680

 Score =  162 bits (410), Expect = 1e-39
 Identities = 92/186 (49%), Positives = 103/186 (55%), Gaps = 16/186 (8%)

Query: 441 LQGPPGPRGPRGDRGSQGPPG---PTGNKGQKGEKGEPGP---PGPAGERGPIGPAGPPG 494
           L G PG +G +G  G  G PG   P GN G +G KG PG    PGP GE GP GPAG PG
Sbjct: 315 LPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPG 374

Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPG---KEGLPGPQGPPGFQGLQG 551
            +G +GS GS G  G  G PG  GP+G  G PGP G PG     GLPGP GP G +G+ G
Sbjct: 375 AKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPG 434

Query: 552 TVGE------PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG-AVVPLALQNEPTPAPED 604
             GE      PG+PG RG  G PG+PG PG KG PG PGP G A +     N PT  P  
Sbjct: 435 HNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGP 494

Query: 605 NGCPPH 610
            G   H
Sbjct: 495 PGPRGH 500



 Score =  158 bits (399), Expect = 2e-38
 Identities = 82/160 (51%), Positives = 91/160 (56%), Gaps = 19/160 (11%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTG--NKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
           GPPGP GPRG  G  GPPG  G  + G +GE G PGPPGP+     +G  G PG  G  G
Sbjct: 63  GPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSA----VGKPGVPGLPGKPG 118

Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP-----PGKEGLPGPQGPPGFQGLQGTVGE 555
            +G  GPKG  G  G PGP+GP G PG PGP     PGK G  GP G PG +G  G  G 
Sbjct: 119 ERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGA 178

Query: 556 PGVPGPR--------GLPGLPGVPGMPGPKGPPGPPGPSG 587
           PGVPG          G PG PG  G+PGP+GP GP GP G
Sbjct: 179 PGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPG 218



 Score =  155 bits (393), Expect = 1e-37
 Identities = 79/147 (53%), Positives = 86/147 (58%), Gaps = 8/147 (5%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAG---PPGERGGK 499
           G PG +G RG  GS G PG  G  G  G KG PG PGP G+ G  GP G   P G  G K
Sbjct: 371 GYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAK 430

Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPG-----FQGLQGTVG 554
           G  G  G  G RG+PG PG +GP G PG PG PG +G PG  GPPG      +GL G  G
Sbjct: 431 GMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTG 490

Query: 555 EPGVPGPRGLPGLPGVPGMPGPKGPPG 581
            PG PGPRG  G PG+PG PGP GPPG
Sbjct: 491 PPGPPGPRGHSGEPGLPGPPGPPGPPG 517



 Score =  152 bits (383), Expect = 1e-36
 Identities = 85/174 (48%), Positives = 94/174 (54%), Gaps = 17/174 (9%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKG-----EPGPPGPAGERGPIGPAGPPG-- 494
           QGP G  GPRG  G +G PG  G  GQKGE G      PG  G  G +GP GP+GPPG  
Sbjct: 161 QGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVG 220

Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL--PGPQGPPGFQGLQGT 552
           +RG  G  G  G KG RG PG+ GP GP G  GPPG  G EG+  PG  G PG  G+ GT
Sbjct: 221 KRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGT 280

Query: 553 VGEPGVPGPR--------GLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598
            G PG PG          G PGLPG+ G  GP G PG PG  G   P  L  +P
Sbjct: 281 KGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKP 334



 Score =  147 bits (371), Expect = 3e-35
 Identities = 86/217 (39%), Positives = 103/217 (47%), Gaps = 61/217 (28%)

Query: 443 GPPGPRGPRGDRGSQG-----------------------------PPGPTGN-------- 465
           GPPGP+GP G+RG +G                             PPGP G         
Sbjct: 247 GPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGL 306

Query: 466 KGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD 525
           KG++G  G PG PG  GE+GP G  G PG  G  G+ G QGPKG  GS G PGP+G +G 
Sbjct: 307 KGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGP 366

Query: 526 PGP---PGPPGKEGLPGPQGPPGFQG---LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGP 579
            GP   PG  G+ G PG  G PG+ G   L G  G PG+PGP+G PG+ G PG+PGP GP
Sbjct: 367 AGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGP 426

Query: 580 ------------------PGPPGPSGAVVPLALQNEP 598
                             PG PG  G + P  +   P
Sbjct: 427 AGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFP 463



 Score =  144 bits (364), Expect = 2e-34
 Identities = 87/202 (43%), Positives = 104/202 (51%), Gaps = 42/202 (20%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP-----PGPAGERGPIGPAGP--- 492
           L G PG RGP G +G  GP G  G +G  G  G PGP     PG  G++GP G  GP   
Sbjct: 113 LPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGF 172

Query: 493 PGERGGKGSKGSQGPKGSR--GSPGK------PGPQGPSGDPGPP--------GPPGKEG 536
           PGE+G  G  G  G KG    G+PG+      PGPQGP+G  GPP        G PG+ G
Sbjct: 173 PGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPG 232

Query: 537 L---------------PGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPG 581
           +               PGPQGPPG +G +G +G+PG  G  G PG+PG  G+PG  G  G
Sbjct: 233 IKGDRGFPGEMGPIGPPGPQGPPGERGPEG-IGKPGAAGAPGQPGIPGTKGLPGAPGIAG 291

Query: 582 PPGPSGAVVP--LALQNEPTPA 601
           PPGP G   P    L+ E  PA
Sbjct: 292 PPGPPGFGKPGLPGLKGERGPA 313



 Score =  109 bits (273), Expect = 8e-24
 Identities = 73/171 (42%), Positives = 84/171 (49%), Gaps = 27/171 (15%)

Query: 442 QGPPGPRGPRGDRGSQG-PPGPTGNKG--QKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498
           Q P G +GP  +  +Q   P    +KG   +GE+G PGPPGPA                 
Sbjct: 26  QMPTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPA----------------- 68

Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV 558
            G +G  GP G  G PG   P G  G+PG PGPPG    P   G PG  GL G  GE G 
Sbjct: 69  -GPRGHPGPSGPPGKPGYGSP-GLQGEPGLPGPPG----PSAVGKPGVPGLPGKPGERGP 122

Query: 559 PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP-LALQNEPTPAPEDNGCP 608
            GP+G  G  G+PG  GP GPPG PGP+G  VP    Q  PT AP   G P
Sbjct: 123 YGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFP 173



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 33/85 (38%), Positives = 40/85 (47%), Gaps = 17/85 (20%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
           +G  GP GP       GPPGP G+ G+ G  G PGPPGP G+   + P G          
Sbjct: 483 KGLNGPTGP------PGPPGPRGHSGEPGLPGPPGPPGPPGQ--AVMPEG--------FI 526

Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDP 526
           K  Q P  S G+P     QG +G P
Sbjct: 527 KAGQRPSLS-GTPLVSANQGVTGMP 550


>gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens]
          Length = 540

 Score =  162 bits (410), Expect = 1e-39
 Identities = 87/196 (44%), Positives = 100/196 (51%), Gaps = 38/196 (19%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP------------IG 488
           L G PG  GP+G++G+ G  GP G++GQ G  G PGPPGP G RGP             G
Sbjct: 152 LDGKPGLPGPKGEKGAPGDFGPRGDQGQDGAAGPPGPPGPPGARGPPGDTGKDGPRGAQG 211

Query: 489 PAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG 548
           PAGP GE G  G  G +GP G +G PG PG +G  G P  PGPPG +G PG  GP G  G
Sbjct: 212 PAGPKGEPGQDGEMGPKGPPGPKGEPGVPGKKGDDGTPSQPGPPGPKGEPGSMGPRGENG 271

Query: 549 LQGTVGEPGVP---------GPRGLPGLPG-----------------VPGMPGPKGPPGP 582
           + G  G  G P         GPRG PGL G                 + G PGP+GPPGP
Sbjct: 272 VDGAPGPKGEPGHRGTDGAAGPRGAPGLKGEQGDTVVIDYDGRILDALKGPPGPQGPPGP 331

Query: 583 PGPSGAVVPLALQNEP 598
           PG  GA   L L   P
Sbjct: 332 PGIPGAKGELGLPGAP 347



 Score =  152 bits (383), Expect = 1e-36
 Identities = 84/177 (47%), Positives = 95/177 (53%), Gaps = 22/177 (12%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGE---KGEPGPPGPAGERGP---IGPAGPPGER 496
           GPPG RG  G RG  GPPG +G  G  G     G+PG PGP GE+G     GP G  G+ 
Sbjct: 121 GPPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDGKPGLPGPKGEKGAPGDFGPRGDQGQD 180

Query: 497 GGKGSKGSQGPKGSRGSP---GKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553
           G  G  G  GP G+RG P   GK GP+G  G  GP G PG++G  GP+GPP      G  
Sbjct: 181 GAAGPPGPPGPPGARGPPGDTGKDGPRGAQGPAGPKGEPGQDGEMGPKGPP------GPK 234

Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPPH 610
           GEPGVPG +G  G P  PG PGPKG PG  GP G       +N    AP   G P H
Sbjct: 235 GEPGVPGKKGDDGTPSQPGPPGPKGEPGSMGPRG-------ENGVDGAPGPKGEPGH 284



 Score =  145 bits (366), Expect = 1e-34
 Identities = 84/209 (40%), Positives = 97/209 (46%), Gaps = 53/209 (25%)

Query: 442 QGPPGPRGPRGDRGSQG---PPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498
           +G PG  GPRGD+G  G   PPGP G  G +G  G+ G  GP G +GP GP G PG+ G 
Sbjct: 165 KGAPGDFGPRGDQGQDGAAGPPGPPGPPGARGPPGDTGKDGPRGAQGPAGPKGEPGQDGE 224

Query: 499 KGSKGSQGPKGSRGSPGK---------PGPQGPSGDPGPPGPPGKEGL---PGPQGPPGF 546
            G KG  GPKG  G PGK         PGP GP G+PG  GP G+ G+   PGP+G PG 
Sbjct: 225 MGPKGPPGPKGEPGVPGKKGDDGTPSQPGPPGPKGEPGSMGPRGENGVDGAPGPKGEPGH 284

Query: 547 QGLQGTVGEPGVPG-----------------------------PRGLP---------GLP 568
           +G  G  G  G PG                             P G P         GLP
Sbjct: 285 RGTDGAAGPRGAPGLKGEQGDTVVIDYDGRILDALKGPPGPQGPPGPPGIPGAKGELGLP 344

Query: 569 GVPGMPGPKGPPGPPGPSGAVVPLALQNE 597
           G PG+ G KGP G  G  G   P  L+ E
Sbjct: 345 GAPGIDGEKGPKGQKGDPGEPGPAGLKGE 373



 Score =  143 bits (360), Expect = 7e-34
 Identities = 87/222 (39%), Positives = 102/222 (45%), Gaps = 58/222 (26%)

Query: 441 LQGPPGPRGP---------RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG--------- 482
           L+GPPGP+GP         +G+ G  G PG  G KG KG+KG+PG PGPAG         
Sbjct: 319 LKGPPGPQGPPGPPGIPGAKGELGLPGAPGIDGEKGPKGQKGDPGEPGPAGLKGEAGEMG 378

Query: 483 -------------------------------ERGPIGPAGPPGERGGKGSKGSQGPKGSR 511
                                          E GP GP GPPG  G +G +G +G  G++
Sbjct: 379 LSGLPGADGLKGEKGESASDSLQESLAQLIVEPGPPGPPGPPGPMGLQGIQGPKGLDGAK 438

Query: 512 GSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGP------PGFQGLQGTVGEPGVPGPRGLP 565
           G  G  G +GPSG PGP GPPG  GLPG +G       PG  G  G  GE G    RG  
Sbjct: 439 GEKGASGERGPSGLPGPVGPPGLIGLPGTKGEKGRPGEPGLDGFPGPRGEKGDRSERGEK 498

Query: 566 GLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGC 607
           G  GVPG  G KG  G PGP G   P  +  +  P P   GC
Sbjct: 499 GERGVPGRKGVKGQKGEPGPPGLDQPCPVGPDGLPVP---GC 537



 Score =  138 bits (348), Expect = 2e-32
 Identities = 80/173 (46%), Positives = 86/173 (49%), Gaps = 31/173 (17%)

Query: 440 ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499
           IL    GP GP      QGPPGP G  G KGE G PG PG  GE+GP G  G PGE G  
Sbjct: 315 ILDALKGPPGP------QGPPGPPGIPGAKGELGLPGAPGIDGEKGPKGQKGDPGEPGPA 368

Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGD-------------------PGPPGPPGKEGLPGP 540
           G KG  G  G  G PG  G +G  G+                   PGPPGPPG  GL G 
Sbjct: 369 GLKGEAGEMGLSGLPGADGLKGEKGESASDSLQESLAQLIVEPGPPGPPGPPGPMGLQGI 428

Query: 541 QGPPGFQGLQGTV------GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           QGP G  G +G        G  G+PGP G PGL G+PG  G KG PG PG  G
Sbjct: 429 QGPKGLDGAKGEKGASGERGPSGLPGPVGPPGLIGLPGTKGEKGRPGEPGLDG 481



 Score =  132 bits (333), Expect = 9e-31
 Identities = 70/161 (43%), Positives = 83/161 (51%), Gaps = 9/161 (5%)

Query: 459 PPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPG 518
           PPGP G +G+ G +G+PGPPG +G  G  GP G  G+       G  GPKG +G+PG  G
Sbjct: 119 PPGPPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDGK------PGLPGPKGEKGAPGDFG 172

Query: 519 PQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGV---PGMPG 575
           P+G  G  G  GPPG  G PG +GPPG  G  G  G  G  GP+G PG  G     G PG
Sbjct: 173 PRGDQGQDGAAGPPGPPGPPGARGPPGDTGKDGPRGAQGPAGPKGEPGQDGEMGPKGPPG 232

Query: 576 PKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPPHWKNFTD 616
           PKG PG PG  G     +    P P  E     P  +N  D
Sbjct: 233 PKGEPGVPGKKGDDGTPSQPGPPGPKGEPGSMGPRGENGVD 273



 Score = 73.2 bits (178), Expect = 8e-13
 Identities = 39/87 (44%), Positives = 46/87 (52%), Gaps = 15/87 (17%)

Query: 520 QGPSGDPGPPGPPGKEGLPGPQGPP---------GFQGLQGTVGEPGVPGPRGLPGLP-- 568
           + PS    PPGPPG+ G PG +G P         G+ G  G  G+PG+PGP+G  G P  
Sbjct: 111 EAPSECVCPPGPPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDGKPGLPGPKGEKGAPGD 170

Query: 569 ----GVPGMPGPKGPPGPPGPSGAVVP 591
               G  G  G  GPPGPPGP GA  P
Sbjct: 171 FGPRGDQGQDGAAGPPGPPGPPGARGP 197


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein
           [Homo sapiens]
          Length = 1650

 Score =  162 bits (409), Expect = 1e-39
 Identities = 89/188 (47%), Positives = 99/188 (52%), Gaps = 30/188 (15%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPG---PAGERGPIGPAGPPGERG 497
           L G PG +GP+G  G  G PG +G KG +G  G+ GP G   P G RG  GP G  G+ G
Sbjct: 714 LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG 773

Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGP---PGPPGKEGLP---------------G 539
            KG+ G  GP G  G  G PGPQGP+G PGP   PGPPGK+GLP               G
Sbjct: 774 AKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTG 833

Query: 540 PQGPPGFQGLQGTVGE---------PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVV 590
           P GPPG  G QG  GE         PG PGP G  GLPG  G  G KG PGPPG  G   
Sbjct: 834 PPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDG 893

Query: 591 PLALQNEP 598
           P  L+  P
Sbjct: 894 PAGLRGFP 901



 Score =  160 bits (404), Expect = 5e-39
 Identities = 83/158 (52%), Positives = 97/158 (61%), Gaps = 9/158 (5%)

Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGP 492
           + F  L G PG +G RGD G+QG PGP G  G++G+ GE GP   PG +G RG +GP GP
Sbjct: 472 RGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGP 531

Query: 493 PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQ---GPPGFQGL 549
           PG  G  G +G  GP+G +GS G   PQG  G PG  G PG +GLPGPQ   GP G +G 
Sbjct: 532 PGIPGPPGVRGMDGPQGPKGSLG---PQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 588

Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           QG  G PG+PG  G PG PG  G PG KG  GP GP G
Sbjct: 589 QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQG 626



 Score =  159 bits (403), Expect = 7e-39
 Identities = 82/164 (50%), Positives = 96/164 (58%), Gaps = 18/164 (10%)

Query: 442 QGPPGPRGPRGDRGSQGPPGP------TGNKGQKGE---KGEPGPPGPAGERGPIGPAGP 492
           +G PGP+GP G  G +GPPGP       G+ GQ+GE   +G+ GPPGP G  GP G AG 
Sbjct: 790 RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGE 849

Query: 493 PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552
            G  G +G  G  GP G +G PG  G +G  GDPGPPG PGK+G  G +G PG +GL GT
Sbjct: 850 TGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGT 909

Query: 553 VGEPGV---------PGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
            G PG+         PGP G PG  G  G  GP GPPG PGP G
Sbjct: 910 AGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQG 953



 Score =  159 bits (402), Expect = 9e-39
 Identities = 84/182 (46%), Positives = 96/182 (52%), Gaps = 36/182 (19%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP---------- 492
           GP G RGP G RG +GP G TG  G KG  G  GP GP GERG  GP GP          
Sbjct: 749 GPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPP 808

Query: 493 -----------PGERGGKGSKGSQGPKGS------RGSPGKPGPQGPSGDPGPPGPPGKE 535
                      PG+RG  G +G  GP G       +G+ G+ GP G  G PGPPGPPG++
Sbjct: 809 GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ 868

Query: 536 GLP---------GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPS 586
           GLP         G  GPPG  G  G  G  G PG RGLPG  G PG+ G +GP GPPGP+
Sbjct: 869 GLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPA 928

Query: 587 GA 588
           G+
Sbjct: 929 GS 930



 Score =  159 bits (402), Expect = 9e-39
 Identities = 84/182 (46%), Positives = 99/182 (54%), Gaps = 30/182 (16%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTG---------------------NKGQKGEKGEPGPPGPA 481
            GPPGP+GP GD G +G PGP G                     ++G+ GE G+PG PGP 
Sbjct: 1163 GPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPT 1222

Query: 482  GERGPIGP------AGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKE 535
            GE GP GP      AG PG  G +G KG++G  G+ G+PGK GP GP+G  G PGP G  
Sbjct: 1223 GENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLR 1282

Query: 536  GLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQ 595
            GLPG  G    QG  G  G+ G PGP G PGLPG+ G  G KG  G PG  G + P   Q
Sbjct: 1283 GLPGSVGQ---QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQ 1339

Query: 596  NE 597
             E
Sbjct: 1340 GE 1341



 Score =  158 bits (399), Expect = 2e-38
 Identities = 82/148 (55%), Positives = 88/148 (59%), Gaps = 12/148 (8%)

Query: 443  GPPGPRGPRGDRGS---QGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499
            GPPGPRGP G  G+   QGPPG  GN G  GEKGEPG  G  G +G  G  GP GERG K
Sbjct: 1094 GPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEK 1153

Query: 500  GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559
            G  G        G PG PGP+GP+GD GP G PG  G PG  GPPG +G  G  G+ G  
Sbjct: 1154 GESGQP------GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG-EG--GPRGQDGAK 1204

Query: 560  GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
            G RG  G PG PG PGP G  GPPGP G
Sbjct: 1205 GDRGEDGEPGQPGSPGPTGENGPPGPLG 1232



 Score =  157 bits (397), Expect = 3e-38
 Identities = 86/167 (51%), Positives = 93/167 (55%), Gaps = 18/167 (10%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---PAGPPG----- 494
            G  GP GP G  G QGPPG  G KG  GEKG  GP G  G +GP+G   PAGPPG     
Sbjct: 938  GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGED 997

Query: 495  ----ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQ 550
                E G  G KG++G KG  G PG PGP GP G PG  G  G+ G  GPQG  G +G +
Sbjct: 998  GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1057

Query: 551  GTVGEPGVPGPRGLPGLPGVPGMP------GPKGPPGPPGPSGAVVP 591
            GT G  G PGP GL GLPG  G        GP GPPGPPGP G   P
Sbjct: 1058 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGP 1104



 Score =  157 bits (396), Expect = 4e-38
 Identities = 81/161 (50%), Positives = 94/161 (58%), Gaps = 3/161 (1%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           GPPG  G +G  G  G PG  G +G KG  G PG PG +GE+G  G +G  G RG +G  
Sbjct: 698 GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 757

Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
           G +G +G RG+ GK G +G SG  GP GPPG+ GLPGPQGP GF G +   G PG PG  
Sbjct: 758 GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK---GPPGPPGKD 814

Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPE 603
           GLPG PG  G  G +G  GPPGP G V P     E  P  E
Sbjct: 815 GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 855



 Score =  157 bits (396), Expect = 4e-38
 Identities = 88/206 (42%), Positives = 94/206 (45%), Gaps = 45/206 (21%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            GPPG  G  GD+G  G PG  G KG KGE G PGPPGP G  G  G AG  GE G +G +
Sbjct: 989  GPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQ 1048

Query: 503  GS------------------------QGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLP 538
            G                          GP G +G  G  GP GP G PGP GP G  G  
Sbjct: 1049 GHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGAD 1108

Query: 539  GPQGP---------------PGFQGLQGTVGEPGVPGPR------GLPGLPGVPGMPGPK 577
            GPQGP               PG  G  G  GEPGV GPR      G  G PG PG PGPK
Sbjct: 1109 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK 1168

Query: 578  GPPGPPGPSGAVVPLALQNEPTPAPE 603
            GP G  GP G   P+    +P P  E
Sbjct: 1169 GPTGDDGPKGNPGPVGFPGDPGPPGE 1194



 Score =  154 bits (390), Expect = 2e-37
 Identities = 82/158 (51%), Positives = 92/158 (58%), Gaps = 15/158 (9%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE---PGPPGPAGERGPIGPAGPPGERGG 498
           +G PG  G +GDRG  G PG  G KG +G+ G    PGPPG  GERG  G  GP G  G 
Sbjct: 460 RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 519

Query: 499 KGSKGSQGPKGSRGSPGKP------GPQGPSGDPGP---PGPPGKEGLPGPQGPPGFQGL 549
            G +G  GPKG  G PG P      GPQGP G  GP   PGPPG++G PG QG P   G 
Sbjct: 520 SGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP---GP 576

Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           QG +G  G  GP+G PGLPG+PG  GP G PG  GP G
Sbjct: 577 QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPG 614



 Score =  153 bits (386), Expect = 6e-37
 Identities = 84/190 (44%), Positives = 98/190 (51%), Gaps = 45/190 (23%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKG------QKGEKGEPGPPGPAGERGPIGPAGPPGE 495
            QG  G  GP G+RG  GPPGP G +G      ++G KG+PGPPG  G+ GP G  G PGE
Sbjct: 844  QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE 903

Query: 496  RG------GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGL 549
            RG      G G KG++GP G  G  G PG +G +G  GP GPPG+   PGPQGPPG  G 
Sbjct: 904  RGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGR---PGPQGPPGAAGE 960

Query: 550  QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPP----------------------------- 580
            +G  GE G  GP G  G+ G  G+PGP GPP                             
Sbjct: 961  KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 1020

Query: 581  -GPPGPSGAV 589
             GPPGP G V
Sbjct: 1021 PGPPGPIGPV 1030



 Score =  152 bits (383), Expect = 1e-36
 Identities = 78/172 (45%), Positives = 95/172 (55%), Gaps = 8/172 (4%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI---GPAGPPGERG 497
            +QG PG +GPRG+RG +G  G  G  G  G KG  G  GP G  GP+   G  GPPGE G
Sbjct: 1137 IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGG 1196

Query: 498  GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557
             +G  G++G +G  G PG+PG  GP+G+ GPPGP GK    GP G PG +G QG  G  G
Sbjct: 1197 PRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR---GPAGSPGSEGRQGGKGAKG 1253

Query: 558  VPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609
             PG  G PG  G  G  GP G PGP G  G  +P ++  +  P       PP
Sbjct: 1254 DPGAIGAPGKTGPVGPAGPAGKPGPDGLRG--LPGSVGQQGRPGATGQAGPP 1303



 Score =  151 bits (382), Expect = 2e-36
 Identities = 77/159 (48%), Positives = 88/159 (55%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            G  GP GP G RG  G PG  G +G KG KG+PG  G  G+ GP+GPAGP G+ G  G +
Sbjct: 1223 GENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLR 1282

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
            G  G  G +G PG  G  GP G  GPPG PG  G  G +G  G  GL G +G PG  G +
Sbjct: 1283 GLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEK 1342

Query: 563  GLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601
            G  GLPG  G PG KG  G PG SG + P      P PA
Sbjct: 1343 GDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPA 1381



 Score =  149 bits (376), Expect = 9e-36
 Identities = 82/171 (47%), Positives = 91/171 (53%), Gaps = 24/171 (14%)

Query: 441 LQGPPGPRGPRGDRGSQGP---PGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERG 497
           L GPPG  G RG  G+ G    PG  G KG +G  G PG PG  G RG  G  G PG  G
Sbjct: 441 LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 500

Query: 498 GKGSKGSQGPKGSRGSPGKPGPQ---GPSGDPGPPGPPGKEGLPGPQGP---------PG 545
             G +G  G  G RG PG+ GP+   GP G PG PGPPG  G+ GPQGP         PG
Sbjct: 501 EDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG 560

Query: 546 FQGLQGTVGEPGVPGPRGL---------PGLPGVPGMPGPKGPPGPPGPSG 587
             G QGT G  G+PGP+G           G PG+PGMPG  GPPG PG  G
Sbjct: 561 PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEG 611



 Score =  147 bits (372), Expect = 3e-35
 Identities = 81/189 (42%), Positives = 97/189 (51%), Gaps = 22/189 (11%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG------PIGPAGPPGER 496
            G PG RGP+G  G++G  G  G  G  G  G  G PGP+GE+G      P+GP GPPG R
Sbjct: 1040 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1099

Query: 497  GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
            G  G  G+ GP+G  G  G  GP G  G+PG  G PG +G PG +GP G +G +G  G+P
Sbjct: 1100 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP 1159

Query: 557  GVP------------GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP----TP 600
            G P            GP+G PG  G PG PGP G  GP G  GA        EP    +P
Sbjct: 1160 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSP 1219

Query: 601  APEDNGCPP 609
             P     PP
Sbjct: 1220 GPTGENGPP 1228



 Score =  145 bits (367), Expect = 1e-34
 Identities = 78/160 (48%), Positives = 86/160 (53%), Gaps = 7/160 (4%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            G  GP GP G  G  GP G  G  G  G++G PG  G AG  GP+GP G PG RG  G+K
Sbjct: 1262 GKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAK 1321

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
            G +G  G  G  G PG QG  GD G PGP G  G  G  G PG  G  G  G PG+PGP 
Sbjct: 1322 GEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPA 1381

Query: 563  GLPGLPGVPGMPGPK------GPPGPPGPSGAVV-PLALQ 595
            G  G  G  G  GPK      GPPG PGP G V+ PL +Q
Sbjct: 1382 GPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQ 1421



 Score =  144 bits (363), Expect = 3e-34
 Identities = 81/170 (47%), Positives = 88/170 (51%), Gaps = 10/170 (5%)

Query: 448 RGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGP 507
           RGP G  G  G PGP G  G  G KGE G  GP G RGP G  GPPG+ G +G  G+ G 
Sbjct: 400 RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 459

Query: 508 KGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGL 567
           +G  G PG  G +G  G PG PG  G  G  G QG PG  G  G  G+ G  GPRGLPG 
Sbjct: 460 RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 519

Query: 568 PGVPGMPGPKGPPGPP---------GPSGAVVPLALQNEPTPAPEDNGCP 608
            G  G+ GPKGPPG P         GP G    L  Q EP P P   G P
Sbjct: 520 SGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP-PGQQGTP 568



 Score =  142 bits (357), Expect = 1e-33
 Identities = 77/160 (48%), Positives = 89/160 (55%), Gaps = 3/160 (1%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
           QG PGP G +G  G+QG PGP G  G  GEKG  G PG  G  G  GP G PG+ G  G+
Sbjct: 556 QGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGT 615

Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG---LQGTVGEPGV 558
           KG+QGP G +G  G PGP+G  G  G  G  G +G  G  G PGF+G   ++G  GE GV
Sbjct: 616 KGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV 675

Query: 559 PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598
           PG RG  G  G  G  GP G PGPPG  G    L +   P
Sbjct: 676 PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLP 715



 Score =  140 bits (354), Expect = 3e-33
 Identities = 75/166 (45%), Positives = 87/166 (52%), Gaps = 9/166 (5%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
           ++G  GP+GP+G  G QG PGP G +G  G +G PGP G  G  G  GP G PG  G  G
Sbjct: 540 VRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 599

Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP- 559
           S G  G  G  G PG  G QGPSG  GP G PG  G+ G  G  G +G +G  GE G P 
Sbjct: 600 SDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPG 659

Query: 560 --------GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNE 597
                   G RG  G+PG  G  GP+GP G  GP+G   P  L  E
Sbjct: 660 FKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGE 705



 Score =  140 bits (353), Expect = 4e-33
 Identities = 78/179 (43%), Positives = 97/179 (54%), Gaps = 11/179 (6%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGE---KGEPGPPGPAGERGPIGPAGPPGERGGK 499
           G  GP+GPRG +G  GPPG  G +G+ G    +G PG PG  G+RG  G  G PGE+G +
Sbjct: 428 GDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHR 487

Query: 500 GSKGSQG------PKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553
           G  G+QG        G RG  G+ GP+G  G+ GP G  G +G PG  GPPG +G+ G  
Sbjct: 488 GDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQ 547

Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP--TPAPEDNGCPPH 610
           G  G  GP+G PG PG  G PG +G PGP G  G       Q +P     P  +G P H
Sbjct: 548 GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 606



 Score =  139 bits (350), Expect = 9e-33
 Identities = 85/197 (43%), Positives = 90/197 (45%), Gaps = 51/197 (25%)

Query: 442 QGPPGPRGPRG---DRGSQGPPGPTGNKGQKGEK-------------------------- 472
           QGP GP+GP G    RG +G  G  G KG KGEK                          
Sbjct: 619 QGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGS 678

Query: 473 -GEPGPPGPAGERGPIGPAGPPGERGGKGS---------KGSQGPKGSRGSPGKP----- 517
            GE GP GP G  GP G  GPPG  G KG           G QGPKGS G PG P     
Sbjct: 679 RGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGE 738

Query: 518 -------GPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGV 570
                  G  GP G+ GP GP G+ G  G  G  G +G  G  G  G PG RGLPG  G 
Sbjct: 739 KGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGP 798

Query: 571 PGMPGPKGPPGPPGPSG 587
            G PGPKGPPGPPG  G
Sbjct: 799 NGFPGPKGPPGPPGKDG 815



 Score =  139 bits (349), Expect = 1e-32
 Identities = 81/181 (44%), Positives = 92/181 (50%), Gaps = 18/181 (9%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG---PPGPAGERGPIGPAGP---PG 494
           L GP G  GP G++G QG PG  G  G  G  G PG   PPG  G +GP GP GP   PG
Sbjct: 573 LPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPG 632

Query: 495 ERGGKGS------KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG 548
            RG KG       KG +G KG  G PG  G  G  GD G  G PG  G  GP+GP G  G
Sbjct: 633 PRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTG 692

Query: 549 LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGP------PGPPGPSGAVVPLALQNEPTPAP 602
             G  G PG+ G +G  G+PG+PG PG +GP      PG PG SG      L  +  P  
Sbjct: 693 PTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG 752

Query: 603 E 603
           E
Sbjct: 753 E 753



 Score =  137 bits (346), Expect = 3e-32
 Identities = 76/152 (50%), Positives = 81/152 (53%), Gaps = 12/152 (7%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG---ERGPIG---PAGPPGER 496
            G  GP G RG  G +G PG  G  G KG +G  GPPGPAG   ERG  G   P GPPG  
Sbjct: 890  GKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGR- 948

Query: 497  GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
                  G QGP G+ G  G PG +GP G  G  G  G  GLPGP GPPG  G  G  GE 
Sbjct: 949  -----PGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 1003

Query: 557  GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588
            G PG +G  G  G  G PGP GP GP G  GA
Sbjct: 1004 GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1035



 Score =  136 bits (342), Expect = 8e-32
 Identities = 76/170 (44%), Positives = 91/170 (53%), Gaps = 12/170 (7%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGE---------KGEPGPPGPAGERGPIGPAG 491
           L+GPPGP G  G  G  G PG  G KG+ G+         +G  GPPG AG RG  G  G
Sbjct: 399 LRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADG 458

Query: 492 PPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQG 551
             G  G  G KG +G  G  G PG+ G +G +G  G PGPPG++G  G  G  G +GL G
Sbjct: 459 ARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPG 518

Query: 552 TVGEPGVPGPRGLPGLPGVP---GMPGPKGPPGPPGPSGAVVPLALQNEP 598
             G  G+ GP+G PG+PG P   GM GP+GP G  GP G   P   Q  P
Sbjct: 519 ESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTP 568



 Score =  136 bits (342), Expect = 8e-32
 Identities = 81/191 (42%), Positives = 94/191 (49%), Gaps = 21/191 (10%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
           L G PG  GP G  G +GPPG  GN+G  G +G  G PGP G +G  G  G  G +G KG
Sbjct: 594 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 653

Query: 501 S------KGSQGPKGSRGSPGKPG------PQGPS------GDPGPP---GPPGKEGLPG 539
                  KG  G KG RG  G PG      P+GP       GDPGPP   G  GK G+PG
Sbjct: 654 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 713

Query: 540 PQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPT 599
             G PG QG +G++G PG PG  G  G  G+ G  GP+G  GP GP G   P     +  
Sbjct: 714 LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG 773

Query: 600 PAPEDNGCPPH 610
                 G  PH
Sbjct: 774 AKGTSGGDGPH 784



 Score =  131 bits (330), Expect = 2e-30
 Identities = 82/216 (37%), Positives = 94/216 (43%), Gaps = 58/216 (26%)

Query: 440 ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGE---- 495
           +++GPPGP GP G     GPPG  GN G  G+ GE GPPG AG  G  G  GPPG     
Sbjct: 310 LVEGPPGPEGPAG---LIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLML 366

Query: 496 ---------------------------------RGGKGSKGSQGPKGSRGSPGKPGPQGP 522
                                            RG  G  G  G  G  G PG PG +G 
Sbjct: 367 PFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGE 426

Query: 523 SGDPGPPGPPGKEGLPGP------QGPPGFQGLQGTVGEPGVPGPRGLPGLPGVP----- 571
           SGD GP GP G +GL GP      +G  G  G +G  G+PGV G RG  GLPG+P     
Sbjct: 427 SGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGH 486

Query: 572 -------GMPGPKGPPGPPGPSGAVVPLALQNEPTP 600
                  G+PGP G  G  G  G + P  L  E  P
Sbjct: 487 RGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGP 522



 Score =  125 bits (314), Expect = 1e-28
 Identities = 70/145 (48%), Positives = 80/145 (55%), Gaps = 9/145 (6%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
            L G  G +G  G  G  GPPGP G  G  G +G+ G  G  G  G IG  GPPGE+G KG
Sbjct: 1284 LPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKG 1343

Query: 501  SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPG 560
             +G  GP+GS G  G+ G  G SG  GP GPPG   LPGP GP G +G  G    PG  G
Sbjct: 1344 DRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPG---LPGPAGPKGAKGATG----PG--G 1394

Query: 561  PRGLPGLPGVPGMPGPKGPPGPPGP 585
            P+G  G+ G PG PGP G    P P
Sbjct: 1395 PKGEKGVQGPPGHPGPPGEVIQPLP 1419



 Score =  107 bits (268), Expect = 3e-23
 Identities = 69/171 (40%), Positives = 75/171 (43%), Gaps = 44/171 (25%)

Query: 461 GPTGNKGQKGE----------KGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGS 510
           GP G KG+KGE          +G PGP GPAG  GP G  G PG  G  G +G  G  G 
Sbjct: 291 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 350

Query: 511 RGSPGKPGPQGPS-----------GDP-----------------------GPPGPPGKEG 536
            GS G PGP G S           GD                        GPPGP G  G
Sbjct: 351 PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTG 410

Query: 537 LPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
            PGP G PG  GL+G  G+ G  GPRG  GL G PG  G +G  G  G  G
Sbjct: 411 RPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARG 461



 Score = 92.0 bits (227), Expect = 2e-18
 Identities = 62/170 (36%), Positives = 68/170 (40%), Gaps = 58/170 (34%)

Query: 464 GNKGQKGEKGEPG--PPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQG 521
           G +G KGEKGEP    PG   E       GPPG          +GP G  G PG  G  G
Sbjct: 291 GPRGLKGEKGEPAVLEPGMLVE-------GPPGP---------EGPAGLIGPPGIQGNPG 334

Query: 522 PSGDPGPPGPPGKEGLPGPQGPPG------------------------------------ 545
           P GDPG  GPPG+ GLPG  G PG                                    
Sbjct: 335 PVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQ 394

Query: 546 ----FQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
                +G  G +G  G PGP G PG PG+ G  G  GP GP GP G   P
Sbjct: 395 ARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGP 444



 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 38/79 (48%), Positives = 45/79 (56%), Gaps = 6/79 (7%)

Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGP--PGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559
           + + GP+G +G  G+P       +PG    GPPG EG  G  GPPG QG  G VG+PG  
Sbjct: 287 EAAHGPRGLKGEKGEPAVL----EPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGER 342

Query: 560 GPRGLPGLPGVPGMPGPKG 578
           GP G  GLPG  G PGP G
Sbjct: 343 GPPGRAGLPGSDGAPGPPG 361



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 40/124 (32%), Positives = 49/124 (39%), Gaps = 37/124 (29%)

Query: 495 ERGGKGSKGSQGPKGSRGSPG-------KPGPQGPSGDPGPPG-----------PPGKEG 536
           E G +    +Q P  ++ SP        +P  Q P      PG           PP +E 
Sbjct: 229 EGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEA 288

Query: 537 LPGPQGPPGFQGLQGTVGE-------------PGVPGPRGLPGLPGVPGMPGPKGPPGPP 583
             GP+G      L+G  GE             PG  GP GL G PG+ G PGP G PG  
Sbjct: 289 AHGPRG------LKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGER 342

Query: 584 GPSG 587
           GP G
Sbjct: 343 GPPG 346



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 25/60 (41%), Positives = 31/60 (51%), Gaps = 6/60 (10%)

Query: 555 EPGVPGPRGLPGLPGVPGMPGP----KGPPGPPGPSGAVVPLALQNEPTPA--PEDNGCP 608
           E    GPRGL G  G P +  P    +GPPGP GP+G + P  +Q  P P   P + G P
Sbjct: 286 EEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPP 345


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein
           [Homo sapiens]
          Length = 1629

 Score =  162 bits (409), Expect = 1e-39
 Identities = 89/188 (47%), Positives = 99/188 (52%), Gaps = 30/188 (15%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPG---PAGERGPIGPAGPPGERG 497
           L G PG +GP+G  G  G PG +G KG +G  G+ GP G   P G RG  GP G  G+ G
Sbjct: 693 LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG 752

Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGP---PGPPGKEGLP---------------G 539
            KG+ G  GP G  G  G PGPQGP+G PGP   PGPPGK+GLP               G
Sbjct: 753 AKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTG 812

Query: 540 PQGPPGFQGLQGTVGE---------PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVV 590
           P GPPG  G QG  GE         PG PGP G  GLPG  G  G KG PGPPG  G   
Sbjct: 813 PPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDG 872

Query: 591 PLALQNEP 598
           P  L+  P
Sbjct: 873 PAGLRGFP 880



 Score =  160 bits (404), Expect = 5e-39
 Identities = 83/158 (52%), Positives = 97/158 (61%), Gaps = 9/158 (5%)

Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGP 492
           + F  L G PG +G RGD G+QG PGP G  G++G+ GE GP   PG +G RG +GP GP
Sbjct: 451 RGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGP 510

Query: 493 PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQ---GPPGFQGL 549
           PG  G  G +G  GP+G +GS G   PQG  G PG  G PG +GLPGPQ   GP G +G 
Sbjct: 511 PGIPGPPGVRGMDGPQGPKGSLG---PQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 567

Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           QG  G PG+PG  G PG PG  G PG KG  GP GP G
Sbjct: 568 QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQG 605



 Score =  159 bits (403), Expect = 7e-39
 Identities = 82/164 (50%), Positives = 96/164 (58%), Gaps = 18/164 (10%)

Query: 442 QGPPGPRGPRGDRGSQGPPGP------TGNKGQKGE---KGEPGPPGPAGERGPIGPAGP 492
           +G PGP+GP G  G +GPPGP       G+ GQ+GE   +G+ GPPGP G  GP G AG 
Sbjct: 769 RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGE 828

Query: 493 PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552
            G  G +G  G  GP G +G PG  G +G  GDPGPPG PGK+G  G +G PG +GL GT
Sbjct: 829 TGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGT 888

Query: 553 VGEPGV---------PGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
            G PG+         PGP G PG  G  G  GP GPPG PGP G
Sbjct: 889 AGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQG 932



 Score =  159 bits (402), Expect = 9e-39
 Identities = 84/182 (46%), Positives = 96/182 (52%), Gaps = 36/182 (19%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP---------- 492
           GP G RGP G RG +GP G TG  G KG  G  GP GP GERG  GP GP          
Sbjct: 728 GPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPP 787

Query: 493 -----------PGERGGKGSKGSQGPKGS------RGSPGKPGPQGPSGDPGPPGPPGKE 535
                      PG+RG  G +G  GP G       +G+ G+ GP G  G PGPPGPPG++
Sbjct: 788 GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ 847

Query: 536 GLP---------GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPS 586
           GLP         G  GPPG  G  G  G  G PG RGLPG  G PG+ G +GP GPPGP+
Sbjct: 848 GLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPA 907

Query: 587 GA 588
           G+
Sbjct: 908 GS 909



 Score =  159 bits (402), Expect = 9e-39
 Identities = 84/182 (46%), Positives = 99/182 (54%), Gaps = 30/182 (16%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTG---------------------NKGQKGEKGEPGPPGPA 481
            GPPGP+GP GD G +G PGP G                     ++G+ GE G+PG PGP 
Sbjct: 1142 GPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPT 1201

Query: 482  GERGPIGP------AGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKE 535
            GE GP GP      AG PG  G +G KG++G  G+ G+PGK GP GP+G  G PGP G  
Sbjct: 1202 GENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLR 1261

Query: 536  GLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQ 595
            GLPG  G    QG  G  G+ G PGP G PGLPG+ G  G KG  G PG  G + P   Q
Sbjct: 1262 GLPGSVGQ---QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQ 1318

Query: 596  NE 597
             E
Sbjct: 1319 GE 1320



 Score =  158 bits (399), Expect = 2e-38
 Identities = 82/148 (55%), Positives = 88/148 (59%), Gaps = 12/148 (8%)

Query: 443  GPPGPRGPRGDRGS---QGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499
            GPPGPRGP G  G+   QGPPG  GN G  GEKGEPG  G  G +G  G  GP GERG K
Sbjct: 1073 GPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEK 1132

Query: 500  GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559
            G  G        G PG PGP+GP+GD GP G PG  G PG  GPPG +G  G  G+ G  
Sbjct: 1133 GESGQP------GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG-EG--GPRGQDGAK 1183

Query: 560  GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
            G RG  G PG PG PGP G  GPPGP G
Sbjct: 1184 GDRGEDGEPGQPGSPGPTGENGPPGPLG 1211



 Score =  157 bits (397), Expect = 3e-38
 Identities = 86/167 (51%), Positives = 93/167 (55%), Gaps = 18/167 (10%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---PAGPPG----- 494
            G  GP GP G  G QGPPG  G KG  GEKG  GP G  G +GP+G   PAGPPG     
Sbjct: 917  GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGED 976

Query: 495  ----ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQ 550
                E G  G KG++G KG  G PG PGP GP G PG  G  G+ G  GPQG  G +G +
Sbjct: 977  GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1036

Query: 551  GTVGEPGVPGPRGLPGLPGVPGMP------GPKGPPGPPGPSGAVVP 591
            GT G  G PGP GL GLPG  G        GP GPPGPPGP G   P
Sbjct: 1037 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGP 1083



 Score =  157 bits (396), Expect = 4e-38
 Identities = 81/161 (50%), Positives = 94/161 (58%), Gaps = 3/161 (1%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           GPPG  G +G  G  G PG  G +G KG  G PG PG +GE+G  G +G  G RG +G  
Sbjct: 677 GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 736

Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
           G +G +G RG+ GK G +G SG  GP GPPG+ GLPGPQGP GF G +   G PG PG  
Sbjct: 737 GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK---GPPGPPGKD 793

Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPE 603
           GLPG PG  G  G +G  GPPGP G V P     E  P  E
Sbjct: 794 GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 834



 Score =  157 bits (396), Expect = 4e-38
 Identities = 88/206 (42%), Positives = 94/206 (45%), Gaps = 45/206 (21%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            GPPG  G  GD+G  G PG  G KG KGE G PGPPGP G  G  G AG  GE G +G +
Sbjct: 968  GPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQ 1027

Query: 503  GS------------------------QGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLP 538
            G                          GP G +G  G  GP GP G PGP GP G  G  
Sbjct: 1028 GHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGAD 1087

Query: 539  GPQGP---------------PGFQGLQGTVGEPGVPGPR------GLPGLPGVPGMPGPK 577
            GPQGP               PG  G  G  GEPGV GPR      G  G PG PG PGPK
Sbjct: 1088 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK 1147

Query: 578  GPPGPPGPSGAVVPLALQNEPTPAPE 603
            GP G  GP G   P+    +P P  E
Sbjct: 1148 GPTGDDGPKGNPGPVGFPGDPGPPGE 1173



 Score =  154 bits (390), Expect = 2e-37
 Identities = 82/158 (51%), Positives = 92/158 (58%), Gaps = 15/158 (9%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE---PGPPGPAGERGPIGPAGPPGERGG 498
           +G PG  G +GDRG  G PG  G KG +G+ G    PGPPG  GERG  G  GP G  G 
Sbjct: 439 RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 498

Query: 499 KGSKGSQGPKGSRGSPGKPG------PQGPSGDPGP---PGPPGKEGLPGPQGPPGFQGL 549
            G +G  GPKG  G PG PG      PQGP G  GP   PGPPG++G PG QG PG    
Sbjct: 499 SGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG---P 555

Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           QG +G  G  GP+G PGLPG+PG  GP G PG  GP G
Sbjct: 556 QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPG 593



 Score =  153 bits (386), Expect = 6e-37
 Identities = 84/190 (44%), Positives = 98/190 (51%), Gaps = 45/190 (23%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKG------QKGEKGEPGPPGPAGERGPIGPAGPPGE 495
            QG  G  GP G+RG  GPPGP G +G      ++G KG+PGPPG  G+ GP G  G PGE
Sbjct: 823  QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE 882

Query: 496  RG------GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGL 549
            RG      G G KG++GP G  G  G PG +G +G  GP GPPG+   PGPQGPPG  G 
Sbjct: 883  RGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGR---PGPQGPPGAAGE 939

Query: 550  QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPP----------------------------- 580
            +G  GE G  GP G  G+ G  G+PGP GPP                             
Sbjct: 940  KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 999

Query: 581  -GPPGPSGAV 589
             GPPGP G V
Sbjct: 1000 PGPPGPIGPV 1009



 Score =  152 bits (383), Expect = 1e-36
 Identities = 78/172 (45%), Positives = 95/172 (55%), Gaps = 8/172 (4%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI---GPAGPPGERG 497
            +QG PG +GPRG+RG +G  G  G  G  G KG  G  GP G  GP+   G  GPPGE G
Sbjct: 1116 IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGG 1175

Query: 498  GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557
             +G  G++G +G  G PG+PG  GP+G+ GPPGP GK    GP G PG +G QG  G  G
Sbjct: 1176 PRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR---GPAGSPGSEGRQGGKGAKG 1232

Query: 558  VPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609
             PG  G PG  G  G  GP G PGP G  G  +P ++  +  P       PP
Sbjct: 1233 DPGAIGAPGKTGPVGPAGPAGKPGPDGLRG--LPGSVGQQGRPGATGQAGPP 1282



 Score =  151 bits (382), Expect = 2e-36
 Identities = 77/159 (48%), Positives = 88/159 (55%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            G  GP GP G RG  G PG  G +G KG KG+PG  G  G+ GP+GPAGP G+ G  G +
Sbjct: 1202 GENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLR 1261

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
            G  G  G +G PG  G  GP G  GPPG PG  G  G +G  G  GL G +G PG  G +
Sbjct: 1262 GLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEK 1321

Query: 563  GLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601
            G  GLPG  G PG KG  G PG SG + P      P PA
Sbjct: 1322 GDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPA 1360



 Score =  149 bits (376), Expect = 9e-36
 Identities = 82/171 (47%), Positives = 91/171 (53%), Gaps = 24/171 (14%)

Query: 441 LQGPPGPRGPRGDRGSQGP---PGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERG 497
           L GPPG  G RG  G+ G    PG  G KG +G  G PG PG  G RG  G  G PG  G
Sbjct: 420 LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 479

Query: 498 GKGSKGSQGPKGSRGSPGKPGPQ---GPSGDPGPPGPPGKEGLPGPQGP---------PG 545
             G +G  G  G RG PG+ GP+   GP G PG PGPPG  G+ GPQGP         PG
Sbjct: 480 EDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG 539

Query: 546 FQGLQGTVGEPGVPGPRGL---------PGLPGVPGMPGPKGPPGPPGPSG 587
             G QGT G  G+PGP+G           G PG+PGMPG  GPPG PG  G
Sbjct: 540 PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEG 590



 Score =  147 bits (372), Expect = 3e-35
 Identities = 81/189 (42%), Positives = 97/189 (51%), Gaps = 22/189 (11%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG------PIGPAGPPGER 496
            G PG RGP+G  G++G  G  G  G  G  G  G PGP+GE+G      P+GP GPPG R
Sbjct: 1019 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1078

Query: 497  GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
            G  G  G+ GP+G  G  G  GP G  G+PG  G PG +G PG +GP G +G +G  G+P
Sbjct: 1079 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP 1138

Query: 557  GVP------------GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP----TP 600
            G P            GP+G PG  G PG PGP G  GP G  GA        EP    +P
Sbjct: 1139 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSP 1198

Query: 601  APEDNGCPP 609
             P     PP
Sbjct: 1199 GPTGENGPP 1207



 Score =  145 bits (367), Expect = 1e-34
 Identities = 78/160 (48%), Positives = 86/160 (53%), Gaps = 7/160 (4%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            G  GP GP G  G  GP G  G  G  G++G PG  G AG  GP+GP G PG RG  G+K
Sbjct: 1241 GKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAK 1300

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
            G +G  G  G  G PG QG  GD G PGP G  G  G  G PG  G  G  G PG+PGP 
Sbjct: 1301 GEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPA 1360

Query: 563  GLPGLPGVPGMPGPK------GPPGPPGPSGAVV-PLALQ 595
            G  G  G  G  GPK      GPPG PGP G V+ PL +Q
Sbjct: 1361 GPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQ 1400



 Score =  144 bits (363), Expect = 3e-34
 Identities = 81/170 (47%), Positives = 88/170 (51%), Gaps = 10/170 (5%)

Query: 448 RGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGP 507
           RGP G  G  G PGP G  G  G KGE G  GP G RGP G  GPPG+ G +G  G+ G 
Sbjct: 379 RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 438

Query: 508 KGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGL 567
           +G  G PG  G +G  G PG PG  G  G  G QG PG  G  G  G+ G  GPRGLPG 
Sbjct: 439 RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 498

Query: 568 PGVPGMPGPKGPPGPP---------GPSGAVVPLALQNEPTPAPEDNGCP 608
            G  G+ GPKGPPG P         GP G    L  Q EP P P   G P
Sbjct: 499 SGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP-PGQQGTP 547



 Score =  142 bits (357), Expect = 1e-33
 Identities = 77/160 (48%), Positives = 89/160 (55%), Gaps = 3/160 (1%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
           QG PGP G +G  G+QG PGP G  G  GEKG  G PG  G  G  GP G PG+ G  G+
Sbjct: 535 QGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGT 594

Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG---LQGTVGEPGV 558
           KG+QGP G +G  G PGP+G  G  G  G  G +G  G  G PGF+G   ++G  GE GV
Sbjct: 595 KGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV 654

Query: 559 PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598
           PG RG  G  G  G  GP G PGPPG  G    L +   P
Sbjct: 655 PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLP 694



 Score =  140 bits (354), Expect = 3e-33
 Identities = 75/166 (45%), Positives = 87/166 (52%), Gaps = 9/166 (5%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
           ++G  GP+GP+G  G QG PGP G +G  G +G PGP G  G  G  GP G PG  G  G
Sbjct: 519 VRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 578

Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP- 559
           S G  G  G  G PG  G QGPSG  GP G PG  G+ G  G  G +G +G  GE G P 
Sbjct: 579 SDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPG 638

Query: 560 --------GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNE 597
                   G RG  G+PG  G  GP+GP G  GP+G   P  L  E
Sbjct: 639 FKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGE 684



 Score =  140 bits (353), Expect = 4e-33
 Identities = 78/179 (43%), Positives = 97/179 (54%), Gaps = 11/179 (6%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGE---KGEPGPPGPAGERGPIGPAGPPGERGGK 499
           G  GP+GPRG +G  GPPG  G +G+ G    +G PG PG  G+RG  G  G PGE+G +
Sbjct: 407 GDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHR 466

Query: 500 GSKGSQG------PKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553
           G  G+QG        G RG  G+ GP+G  G+ GP G  G +G PG  GPPG +G+ G  
Sbjct: 467 GDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQ 526

Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP--TPAPEDNGCPPH 610
           G  G  GP+G PG PG  G PG +G PGP G  G       Q +P     P  +G P H
Sbjct: 527 GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 585



 Score =  139 bits (350), Expect = 9e-33
 Identities = 85/197 (43%), Positives = 90/197 (45%), Gaps = 51/197 (25%)

Query: 442 QGPPGPRGPRG---DRGSQGPPGPTGNKGQKGEK-------------------------- 472
           QGP GP+GP G    RG +G  G  G KG KGEK                          
Sbjct: 598 QGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGS 657

Query: 473 -GEPGPPGPAGERGPIGPAGPPGERGGKGS---------KGSQGPKGSRGSPGKP----- 517
            GE GP GP G  GP G  GPPG  G KG           G QGPKGS G PG P     
Sbjct: 658 RGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGE 717

Query: 518 -------GPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGV 570
                  G  GP G+ GP GP G+ G  G  G  G +G  G  G  G PG RGLPG  G 
Sbjct: 718 KGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGP 777

Query: 571 PGMPGPKGPPGPPGPSG 587
            G PGPKGPPGPPG  G
Sbjct: 778 NGFPGPKGPPGPPGKDG 794



 Score =  139 bits (349), Expect = 1e-32
 Identities = 81/181 (44%), Positives = 92/181 (50%), Gaps = 18/181 (9%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG---PPGPAGERGPIGPAGP---PG 494
           L GP G  GP G++G QG PG  G  G  G  G PG   PPG  G +GP GP GP   PG
Sbjct: 552 LPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPG 611

Query: 495 ERGGKGS------KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG 548
            RG KG       KG +G KG  G PG  G  G  GD G  G PG  G  GP+GP G  G
Sbjct: 612 PRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTG 671

Query: 549 LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGP------PGPPGPSGAVVPLALQNEPTPAP 602
             G  G PG+ G +G  G+PG+PG PG +GP      PG PG SG      L  +  P  
Sbjct: 672 PTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG 731

Query: 603 E 603
           E
Sbjct: 732 E 732



 Score =  137 bits (346), Expect = 3e-32
 Identities = 76/152 (50%), Positives = 81/152 (53%), Gaps = 12/152 (7%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG---ERGPIG---PAGPPGER 496
            G  GP G RG  G +G PG  G  G KG +G  GPPGPAG   ERG  G   P GPPG  
Sbjct: 869  GKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGR- 927

Query: 497  GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
                  G QGP G+ G  G PG +GP G  G  G  G  GLPGP GPPG  G  G  GE 
Sbjct: 928  -----PGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 982

Query: 557  GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588
            G PG +G  G  G  G PGP GP GP G  GA
Sbjct: 983  GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1014



 Score =  136 bits (342), Expect = 8e-32
 Identities = 76/170 (44%), Positives = 91/170 (53%), Gaps = 12/170 (7%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGE---------KGEPGPPGPAGERGPIGPAG 491
           L+GPPGP G  G  G  G PG  G KG+ G+         +G  GPPG AG RG  G  G
Sbjct: 378 LRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADG 437

Query: 492 PPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQG 551
             G  G  G KG +G  G  G PG+ G +G +G  G PGPPG++G  G  G  G +GL G
Sbjct: 438 ARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPG 497

Query: 552 TVGEPGVPGPRGLPGLPGVP---GMPGPKGPPGPPGPSGAVVPLALQNEP 598
             G  G+ GP+G PG+PG P   GM GP+GP G  GP G   P   Q  P
Sbjct: 498 ESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTP 547



 Score =  136 bits (342), Expect = 8e-32
 Identities = 81/191 (42%), Positives = 94/191 (49%), Gaps = 21/191 (10%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
           L G PG  GP G  G +GPPG  GN+G  G +G  G PGP G +G  G  G  G +G KG
Sbjct: 573 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 632

Query: 501 S------KGSQGPKGSRGSPGKPG------PQGPS------GDPGPP---GPPGKEGLPG 539
                  KG  G KG RG  G PG      P+GP       GDPGPP   G  GK G+PG
Sbjct: 633 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 692

Query: 540 PQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPT 599
             G PG QG +G++G PG PG  G  G  G+ G  GP+G  GP GP G   P     +  
Sbjct: 693 LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG 752

Query: 600 PAPEDNGCPPH 610
                 G  PH
Sbjct: 753 AKGTSGGDGPH 763



 Score =  131 bits (330), Expect = 2e-30
 Identities = 82/216 (37%), Positives = 94/216 (43%), Gaps = 58/216 (26%)

Query: 440 ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGE---- 495
           +++GPPGP GP G     GPPG  GN G  G+ GE GPPG AG  G  G  GPPG     
Sbjct: 289 LVEGPPGPEGPAG---LIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLML 345

Query: 496 ---------------------------------RGGKGSKGSQGPKGSRGSPGKPGPQGP 522
                                            RG  G  G  G  G  G PG PG +G 
Sbjct: 346 PFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGE 405

Query: 523 SGDPGPPGPPGKEGLPGP------QGPPGFQGLQGTVGEPGVPGPRGLPGLPGVP----- 571
           SGD GP GP G +GL GP      +G  G  G +G  G+PGV G RG  GLPG+P     
Sbjct: 406 SGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGH 465

Query: 572 -------GMPGPKGPPGPPGPSGAVVPLALQNEPTP 600
                  G+PGP G  G  G  G + P  L  E  P
Sbjct: 466 RGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGP 501



 Score =  125 bits (314), Expect = 1e-28
 Identities = 70/145 (48%), Positives = 80/145 (55%), Gaps = 9/145 (6%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
            L G  G +G  G  G  GPPGP G  G  G +G+ G  G  G  G IG  GPPGE+G KG
Sbjct: 1263 LPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKG 1322

Query: 501  SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPG 560
             +G  GP+GS G  G+ G  G SG  GP GPP   GLPGP GP G +G  G    PG  G
Sbjct: 1323 DRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP---GLPGPAGPKGAKGATG----PG--G 1373

Query: 561  PRGLPGLPGVPGMPGPKGPPGPPGP 585
            P+G  G+ G PG PGP G    P P
Sbjct: 1374 PKGEKGVQGPPGHPGPPGEVIQPLP 1398



 Score = 92.4 bits (228), Expect = 1e-18
 Identities = 65/178 (36%), Positives = 71/178 (39%), Gaps = 61/178 (34%)

Query: 456 SQGPPGPTGNKGQKGEKGEPG--PPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGS 513
           SQ   GP   +G KGEKGEP    PG   E       GPPG          +GP G  G 
Sbjct: 265 SQAAHGP---RGLKGEKGEPAVLEPGMLVE-------GPPGP---------EGPAGLIGP 305

Query: 514 PGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPG---------------------------- 545
           PG  G  GP GDPG  GPPG+ GLPG  G PG                            
Sbjct: 306 PGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEA 365

Query: 546 ------------FQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
                        +G  G +G  G PGP G PG PG+ G  G  GP GP GP G   P
Sbjct: 366 QAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGP 423



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 27/63 (42%), Positives = 30/63 (47%), Gaps = 13/63 (20%)

Query: 538 PGPQGPPGFQGLQGTVGE-------------PGVPGPRGLPGLPGVPGMPGPKGPPGPPG 584
           P  Q   G +GL+G  GE             PG  GP GL G PG+ G PGP G PG  G
Sbjct: 263 PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 322

Query: 585 PSG 587
           P G
Sbjct: 323 PPG 325


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein
           [Homo sapiens]
          Length = 1736

 Score =  162 bits (409), Expect = 1e-39
 Identities = 89/188 (47%), Positives = 99/188 (52%), Gaps = 30/188 (15%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPG---PAGERGPIGPAGPPGERG 497
           L G PG +GP+G  G  G PG +G KG +G  G+ GP G   P G RG  GP G  G+ G
Sbjct: 800 LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG 859

Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGP---PGPPGKEGLP---------------G 539
            KG+ G  GP G  G  G PGPQGP+G PGP   PGPPGK+GLP               G
Sbjct: 860 AKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTG 919

Query: 540 PQGPPGFQGLQGTVGE---------PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVV 590
           P GPPG  G QG  GE         PG PGP G  GLPG  G  G KG PGPPG  G   
Sbjct: 920 PPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDG 979

Query: 591 PLALQNEP 598
           P  L+  P
Sbjct: 980 PAGLRGFP 987



 Score =  160 bits (404), Expect = 5e-39
 Identities = 83/158 (52%), Positives = 97/158 (61%), Gaps = 9/158 (5%)

Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGP 492
           + F  L G PG +G RGD G+QG PGP G  G++G+ GE GP   PG +G RG +GP GP
Sbjct: 558 RGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGP 617

Query: 493 PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQ---GPPGFQGL 549
           PG  G  G +G  GP+G +GS G   PQG  G PG  G PG +GLPGPQ   GP G +G 
Sbjct: 618 PGIPGPPGVRGMDGPQGPKGSLG---PQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 674

Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           QG  G PG+PG  G PG PG  G PG KG  GP GP G
Sbjct: 675 QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQG 712



 Score =  159 bits (403), Expect = 7e-39
 Identities = 80/158 (50%), Positives = 92/158 (58%), Gaps = 12/158 (7%)

Query: 442  QGP---PGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498
            QGP   PGP+GP G  G  G PG  G +G+ G +G+ GPPGP G  GP G AG  G  G 
Sbjct: 882  QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 941

Query: 499  KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV 558
            +G  G  GP G +G PG  G +G  GDPGPPG PGK+G  G +G PG +GL GT G PG+
Sbjct: 942  RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGL 1001

Query: 559  ---------PGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
                     PGP G PG  G  G  GP GPPG PGP G
Sbjct: 1002 KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQG 1039



 Score =  159 bits (402), Expect = 9e-39
 Identities = 84/182 (46%), Positives = 96/182 (52%), Gaps = 36/182 (19%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP---------- 492
            GP G RGP G RG +GP G TG  G KG  G  GP GP GERG  GP GP          
Sbjct: 835  GPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPP 894

Query: 493  -----------PGERGGKGSKGSQGPKGS------RGSPGKPGPQGPSGDPGPPGPPGKE 535
                       PG+RG  G +G  GP G       +G+ G+ GP G  G PGPPGPPG++
Sbjct: 895  GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ 954

Query: 536  GLP---------GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPS 586
            GLP         G  GPPG  G  G  G  G PG RGLPG  G PG+ G +GP GPPGP+
Sbjct: 955  GLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPA 1014

Query: 587  GA 588
            G+
Sbjct: 1015 GS 1016



 Score =  159 bits (402), Expect = 9e-39
 Identities = 84/182 (46%), Positives = 99/182 (54%), Gaps = 30/182 (16%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTG---------------------NKGQKGEKGEPGPPGPA 481
            GPPGP+GP GD G +G PGP G                     ++G+ GE G+PG PGP 
Sbjct: 1249 GPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPT 1308

Query: 482  GERGPIGP------AGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKE 535
            GE GP GP      AG PG  G +G KG++G  G+ G+PGK GP GP+G  G PGP G  
Sbjct: 1309 GENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLR 1368

Query: 536  GLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQ 595
            GLPG  G    QG  G  G+ G PGP G PGLPG+ G  G KG  G PG  G + P   Q
Sbjct: 1369 GLPGSVGQ---QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQ 1425

Query: 596  NE 597
             E
Sbjct: 1426 GE 1427



 Score =  158 bits (399), Expect = 2e-38
 Identities = 82/148 (55%), Positives = 88/148 (59%), Gaps = 12/148 (8%)

Query: 443  GPPGPRGPRGDRGS---QGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499
            GPPGPRGP G  G+   QGPPG  GN G  GEKGEPG  G  G +G  G  GP GERG K
Sbjct: 1180 GPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEK 1239

Query: 500  GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559
            G  G        G PG PGP+GP+GD GP G PG  G PG  GPPG +G  G  G+ G  
Sbjct: 1240 GESGQP------GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG-EG--GPRGQDGAK 1290

Query: 560  GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
            G RG  G PG PG PGP G  GPPGP G
Sbjct: 1291 GDRGEDGEPGQPGSPGPTGENGPPGPLG 1318



 Score =  157 bits (397), Expect = 3e-38
 Identities = 86/167 (51%), Positives = 93/167 (55%), Gaps = 18/167 (10%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---PAGPPG----- 494
            G  GP GP G  G QGPPG  G KG  GEKG  GP G  G +GP+G   PAGPPG     
Sbjct: 1024 GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGED 1083

Query: 495  ----ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQ 550
                E G  G KG++G KG  G PG PGP GP G PG  G  G+ G  GPQG  G +G +
Sbjct: 1084 GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1143

Query: 551  GTVGEPGVPGPRGLPGLPGVPGMP------GPKGPPGPPGPSGAVVP 591
            GT G  G PGP GL GLPG  G        GP GPPGPPGP G   P
Sbjct: 1144 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGP 1190



 Score =  157 bits (396), Expect = 4e-38
 Identities = 81/161 (50%), Positives = 94/161 (58%), Gaps = 3/161 (1%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           GPPG  G +G  G  G PG  G +G KG  G PG PG +GE+G  G +G  G RG +G  
Sbjct: 784 GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 843

Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
           G +G +G RG+ GK G +G SG  GP GPPG+ GLPGPQGP GF G +   G PG PG  
Sbjct: 844 GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK---GPPGPPGKD 900

Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPE 603
           GLPG PG  G  G +G  GPPGP G V P     E  P  E
Sbjct: 901 GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 941



 Score =  157 bits (396), Expect = 4e-38
 Identities = 88/206 (42%), Positives = 94/206 (45%), Gaps = 45/206 (21%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            GPPG  G  GD+G  G PG  G KG KGE G PGPPGP G  G  G AG  GE G +G +
Sbjct: 1075 GPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQ 1134

Query: 503  GS------------------------QGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLP 538
            G                          GP G +G  G  GP GP G PGP GP G  G  
Sbjct: 1135 GHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGAD 1194

Query: 539  GPQGP---------------PGFQGLQGTVGEPGVPGPR------GLPGLPGVPGMPGPK 577
            GPQGP               PG  G  G  GEPGV GPR      G  G PG PG PGPK
Sbjct: 1195 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK 1254

Query: 578  GPPGPPGPSGAVVPLALQNEPTPAPE 603
            GP G  GP G   P+    +P P  E
Sbjct: 1255 GPTGDDGPKGNPGPVGFPGDPGPPGE 1280



 Score =  154 bits (390), Expect = 2e-37
 Identities = 82/158 (51%), Positives = 92/158 (58%), Gaps = 15/158 (9%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE---PGPPGPAGERGPIGPAGPPGERGG 498
           +G PG  G +GDRG  G PG  G KG +G+ G    PGPPG  GERG  G  GP G  G 
Sbjct: 546 RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 605

Query: 499 KGSKGSQGPKGSRGSPGKP------GPQGPSGDPGP---PGPPGKEGLPGPQGPPGFQGL 549
            G +G  GPKG  G PG P      GPQGP G  GP   PGPPG++G PG QG P   G 
Sbjct: 606 SGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP---GP 662

Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           QG +G  G  GP+G PGLPG+PG  GP G PG  GP G
Sbjct: 663 QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPG 700



 Score =  153 bits (386), Expect = 6e-37
 Identities = 84/190 (44%), Positives = 98/190 (51%), Gaps = 45/190 (23%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKG------QKGEKGEPGPPGPAGERGPIGPAGPPGE 495
            QG  G  GP G+RG  GPPGP G +G      ++G KG+PGPPG  G+ GP G  G PGE
Sbjct: 930  QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE 989

Query: 496  RG------GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGL 549
            RG      G G KG++GP G  G  G PG +G +G  GP GPPG+   PGPQGPPG  G 
Sbjct: 990  RGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGR---PGPQGPPGAAGE 1046

Query: 550  QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPP----------------------------- 580
            +G  GE G  GP G  G+ G  G+PGP GPP                             
Sbjct: 1047 KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 1106

Query: 581  -GPPGPSGAV 589
             GPPGP G V
Sbjct: 1107 PGPPGPIGPV 1116



 Score =  152 bits (383), Expect = 1e-36
 Identities = 78/172 (45%), Positives = 95/172 (55%), Gaps = 8/172 (4%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI---GPAGPPGERG 497
            +QG PG +GPRG+RG +G  G  G  G  G KG  G  GP G  GP+   G  GPPGE G
Sbjct: 1223 IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGG 1282

Query: 498  GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557
             +G  G++G +G  G PG+PG  GP+G+ GPPGP GK    GP G PG +G QG  G  G
Sbjct: 1283 PRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR---GPAGSPGSEGRQGGKGAKG 1339

Query: 558  VPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609
             PG  G PG  G  G  GP G PGP G  G  +P ++  +  P       PP
Sbjct: 1340 DPGAIGAPGKTGPVGPAGPAGKPGPDGLRG--LPGSVGQQGRPGATGQAGPP 1389



 Score =  151 bits (382), Expect = 2e-36
 Identities = 77/159 (48%), Positives = 88/159 (55%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            G  GP GP G RG  G PG  G +G KG KG+PG  G  G+ GP+GPAGP G+ G  G +
Sbjct: 1309 GENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLR 1368

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
            G  G  G +G PG  G  GP G  GPPG PG  G  G +G  G  GL G +G PG  G +
Sbjct: 1369 GLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEK 1428

Query: 563  GLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601
            G  GLPG  G PG KG  G PG SG + P      P PA
Sbjct: 1429 GDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPA 1467



 Score =  149 bits (376), Expect = 9e-36
 Identities = 82/171 (47%), Positives = 91/171 (53%), Gaps = 24/171 (14%)

Query: 441 LQGPPGPRGPRGDRGSQGP---PGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERG 497
           L GPPG  G RG  G+ G    PG  G KG +G  G PG PG  G RG  G  G PG  G
Sbjct: 527 LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 586

Query: 498 GKGSKGSQGPKGSRGSPGKPGPQ---GPSGDPGPPGPPGKEGLPGPQGP---------PG 545
             G +G  G  G RG PG+ GP+   GP G PG PGPPG  G+ GPQGP         PG
Sbjct: 587 EDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG 646

Query: 546 FQGLQGTVGEPGVPGPRGL---------PGLPGVPGMPGPKGPPGPPGPSG 587
             G QGT G  G+PGP+G           G PG+PGMPG  GPPG PG  G
Sbjct: 647 PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEG 697



 Score =  147 bits (372), Expect = 3e-35
 Identities = 81/189 (42%), Positives = 97/189 (51%), Gaps = 22/189 (11%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG------PIGPAGPPGER 496
            G PG RGP+G  G++G  G  G  G  G  G  G PGP+GE+G      P+GP GPPG R
Sbjct: 1126 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1185

Query: 497  GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
            G  G  G+ GP+G  G  G  GP G  G+PG  G PG +G PG +GP G +G +G  G+P
Sbjct: 1186 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP 1245

Query: 557  GVP------------GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP----TP 600
            G P            GP+G PG  G PG PGP G  GP G  GA        EP    +P
Sbjct: 1246 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSP 1305

Query: 601  APEDNGCPP 609
             P     PP
Sbjct: 1306 GPTGENGPP 1314



 Score =  145 bits (367), Expect = 1e-34
 Identities = 78/160 (48%), Positives = 86/160 (53%), Gaps = 7/160 (4%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            G  GP GP G  G  GP G  G  G  G++G PG  G AG  GP+GP G PG RG  G+K
Sbjct: 1348 GKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAK 1407

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
            G +G  G  G  G PG QG  GD G PGP G  G  G  G PG  G  G  G PG+PGP 
Sbjct: 1408 GEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPA 1467

Query: 563  GLPGLPGVPGMPGPK------GPPGPPGPSGAVV-PLALQ 595
            G  G  G  G  GPK      GPPG PGP G V+ PL +Q
Sbjct: 1468 GPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQ 1507



 Score =  144 bits (363), Expect = 3e-34
 Identities = 81/170 (47%), Positives = 88/170 (51%), Gaps = 10/170 (5%)

Query: 448 RGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGP 507
           RGP G  G  G PGP G  G  G KGE G  GP G RGP G  GPPG+ G +G  G+ G 
Sbjct: 486 RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 545

Query: 508 KGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGL 567
           +G  G PG  G +G  G PG PG  G  G  G QG PG  G  G  G+ G  GPRGLPG 
Sbjct: 546 RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 605

Query: 568 PGVPGMPGPKGPPGPP---------GPSGAVVPLALQNEPTPAPEDNGCP 608
            G  G+ GPKGPPG P         GP G    L  Q EP P P   G P
Sbjct: 606 SGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP-PGQQGTP 654



 Score =  142 bits (357), Expect = 1e-33
 Identities = 77/160 (48%), Positives = 89/160 (55%), Gaps = 3/160 (1%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
           QG PGP G +G  G+QG PGP G  G  GEKG  G PG  G  G  GP G PG+ G  G+
Sbjct: 642 QGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGT 701

Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG---LQGTVGEPGV 558
           KG+QGP G +G  G PGP+G  G  G  G  G +G  G  G PGF+G   ++G  GE GV
Sbjct: 702 KGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV 761

Query: 559 PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598
           PG RG  G  G  G  GP G PGPPG  G    L +   P
Sbjct: 762 PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLP 801



 Score =  140 bits (354), Expect = 3e-33
 Identities = 75/166 (45%), Positives = 87/166 (52%), Gaps = 9/166 (5%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
           ++G  GP+GP+G  G QG PGP G +G  G +G PGP G  G  G  GP G PG  G  G
Sbjct: 626 VRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 685

Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP- 559
           S G  G  G  G PG  G QGPSG  GP G PG  G+ G  G  G +G +G  GE G P 
Sbjct: 686 SDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPG 745

Query: 560 --------GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNE 597
                   G RG  G+PG  G  GP+GP G  GP+G   P  L  E
Sbjct: 746 FKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGE 791



 Score =  140 bits (353), Expect = 4e-33
 Identities = 78/179 (43%), Positives = 97/179 (54%), Gaps = 11/179 (6%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGE---KGEPGPPGPAGERGPIGPAGPPGERGGK 499
           G  GP+GPRG +G  GPPG  G +G+ G    +G PG PG  G+RG  G  G PGE+G +
Sbjct: 514 GDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHR 573

Query: 500 GSKGSQG------PKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553
           G  G+QG        G RG  G+ GP+G  G+ GP G  G +G PG  GPPG +G+ G  
Sbjct: 574 GDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQ 633

Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP--TPAPEDNGCPPH 610
           G  G  GP+G PG PG  G PG +G PGP G  G       Q +P     P  +G P H
Sbjct: 634 GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 692



 Score =  139 bits (350), Expect = 9e-33
 Identities = 85/197 (43%), Positives = 90/197 (45%), Gaps = 51/197 (25%)

Query: 442 QGPPGPRGPRG---DRGSQGPPGPTGNKGQKGEK-------------------------- 472
           QGP GP+GP G    RG +G  G  G KG KGEK                          
Sbjct: 705 QGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGS 764

Query: 473 -GEPGPPGPAGERGPIGPAGPPGERGGKGS---------KGSQGPKGSRGSPGKP----- 517
            GE GP GP G  GP G  GPPG  G KG           G QGPKGS G PG P     
Sbjct: 765 RGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGE 824

Query: 518 -------GPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGV 570
                  G  GP G+ GP GP G+ G  G  G  G +G  G  G  G PG RGLPG  G 
Sbjct: 825 KGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGP 884

Query: 571 PGMPGPKGPPGPPGPSG 587
            G PGPKGPPGPPG  G
Sbjct: 885 NGFPGPKGPPGPPGKDG 901



 Score =  139 bits (349), Expect = 1e-32
 Identities = 81/181 (44%), Positives = 92/181 (50%), Gaps = 18/181 (9%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG---PPGPAGERGPIGPAGP---PG 494
           L GP G  GP G++G QG PG  G  G  G  G PG   PPG  G +GP GP GP   PG
Sbjct: 659 LPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPG 718

Query: 495 ERGGKGS------KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG 548
            RG KG       KG +G KG  G PG  G  G  GD G  G PG  G  GP+GP G  G
Sbjct: 719 PRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTG 778

Query: 549 LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGP------PGPPGPSGAVVPLALQNEPTPAP 602
             G  G PG+ G +G  G+PG+PG PG +GP      PG PG SG      L  +  P  
Sbjct: 779 PTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG 838

Query: 603 E 603
           E
Sbjct: 839 E 839



 Score =  137 bits (346), Expect = 3e-32
 Identities = 76/152 (50%), Positives = 81/152 (53%), Gaps = 12/152 (7%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG---ERGPIG---PAGPPGER 496
            G  GP G RG  G +G PG  G  G KG +G  GPPGPAG   ERG  G   P GPPG  
Sbjct: 976  GKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGR- 1034

Query: 497  GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
                  G QGP G+ G  G PG +GP G  G  G  G  GLPGP GPPG  G  G  GE 
Sbjct: 1035 -----PGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 1089

Query: 557  GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588
            G PG +G  G  G  G PGP GP GP G  GA
Sbjct: 1090 GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1121



 Score =  136 bits (342), Expect = 8e-32
 Identities = 76/170 (44%), Positives = 91/170 (53%), Gaps = 12/170 (7%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGE---------KGEPGPPGPAGERGPIGPAG 491
           L+GPPGP G  G  G  G PG  G KG+ G+         +G  GPPG AG RG  G  G
Sbjct: 485 LRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADG 544

Query: 492 PPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQG 551
             G  G  G KG +G  G  G PG+ G +G +G  G PGPPG++G  G  G  G +GL G
Sbjct: 545 ARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPG 604

Query: 552 TVGEPGVPGPRGLPGLPGVP---GMPGPKGPPGPPGPSGAVVPLALQNEP 598
             G  G+ GP+G PG+PG P   GM GP+GP G  GP G   P   Q  P
Sbjct: 605 ESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTP 654



 Score =  136 bits (342), Expect = 8e-32
 Identities = 81/191 (42%), Positives = 94/191 (49%), Gaps = 21/191 (10%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
           L G PG  GP G  G +GPPG  GN+G  G +G  G PGP G +G  G  G  G +G KG
Sbjct: 680 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 739

Query: 501 S------KGSQGPKGSRGSPGKPG------PQGPS------GDPGPP---GPPGKEGLPG 539
                  KG  G KG RG  G PG      P+GP       GDPGPP   G  GK G+PG
Sbjct: 740 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 799

Query: 540 PQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPT 599
             G PG QG +G++G PG PG  G  G  G+ G  GP+G  GP GP G   P     +  
Sbjct: 800 LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG 859

Query: 600 PAPEDNGCPPH 610
                 G  PH
Sbjct: 860 AKGTSGGDGPH 870



 Score =  131 bits (330), Expect = 2e-30
 Identities = 82/216 (37%), Positives = 94/216 (43%), Gaps = 58/216 (26%)

Query: 440 ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGE---- 495
           +++GPPGP GP G     GPPG  GN G  G+ GE GPPG AG  G  G  GPPG     
Sbjct: 396 LVEGPPGPEGPAG---LIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLML 452

Query: 496 ---------------------------------RGGKGSKGSQGPKGSRGSPGKPGPQGP 522
                                            RG  G  G  G  G  G PG PG +G 
Sbjct: 453 PFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGE 512

Query: 523 SGDPGPPGPPGKEGLPGP------QGPPGFQGLQGTVGEPGVPGPRGLPGLPGVP----- 571
           SGD GP GP G +GL GP      +G  G  G +G  G+PGV G RG  GLPG+P     
Sbjct: 513 SGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGH 572

Query: 572 -------GMPGPKGPPGPPGPSGAVVPLALQNEPTP 600
                  G+PGP G  G  G  G + P  L  E  P
Sbjct: 573 RGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGP 608



 Score =  125 bits (314), Expect = 1e-28
 Identities = 70/145 (48%), Positives = 80/145 (55%), Gaps = 9/145 (6%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
            L G  G +G  G  G  GPPGP G  G  G +G+ G  G  G  G IG  GPPGE+G KG
Sbjct: 1370 LPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKG 1429

Query: 501  SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPG 560
             +G  GP+GS G  G+ G  G SG  GP GPP   GLPGP GP G +G  G    PG  G
Sbjct: 1430 DRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP---GLPGPAGPKGAKGATG----PG--G 1480

Query: 561  PRGLPGLPGVPGMPGPKGPPGPPGP 585
            P+G  G+ G PG PGP G    P P
Sbjct: 1481 PKGEKGVQGPPGHPGPPGEVIQPLP 1505



 Score =  107 bits (268), Expect = 3e-23
 Identities = 69/171 (40%), Positives = 75/171 (43%), Gaps = 44/171 (25%)

Query: 461 GPTGNKGQKGE----------KGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGS 510
           GP G KG+KGE          +G PGP GPAG  GP G  G PG  G  G +G  G  G 
Sbjct: 377 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 436

Query: 511 RGSPGKPGPQGPS-----------GDP-----------------------GPPGPPGKEG 536
            GS G PGP G S           GD                        GPPGP G  G
Sbjct: 437 PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTG 496

Query: 537 LPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
            PGP G PG  GL+G  G+ G  GPRG  GL G PG  G +G  G  G  G
Sbjct: 497 RPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARG 547



 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 53/132 (40%), Positives = 63/132 (47%), Gaps = 21/132 (15%)

Query: 462 PTGNKGQKGEKGEPGPPGPAG-------------ERGPIGPAGPPGERGGKGSKGSQGPK 508
           PT ++ Q  E GE G   P G             E   +GPA    E    G+  + GP+
Sbjct: 322 PTADRFQAEEYGEGGTDPPEGPYDYTYGYGDDYREETELGPA-LSAETAHSGA-AAHGPR 379

Query: 509 GSRGSPGKPGPQGPSGDPGP--PGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPG 566
           G +G  G+P       +PG    GPPG EG  G  GPPG QG  G VG+PG  GP G  G
Sbjct: 380 GLKGEKGEPAVL----EPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAG 435

Query: 567 LPGVPGMPGPKG 578
           LPG  G PGP G
Sbjct: 436 LPGSDGAPGPPG 447


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score =  161 bits (408), Expect = 2e-39
 Identities = 95/219 (43%), Positives = 108/219 (49%), Gaps = 53/219 (24%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTG------------------NKGQKGEKGEPGPPGPAGER 484
           GP GPRG  G+RG  GP GP G                   KG KGE G  GP GP G  
Sbjct: 703 GPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAA 762

Query: 485 GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSG---DPGPPGPPGKEGLPGPQ 541
           GP GP GPPG  G +G  G  G  G  G+ G+ GP GPSG    PGPPGP GKEGL GP+
Sbjct: 763 GPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPR 822

Query: 542 G---------------PPGFQGLQG------TVGEPGVPGPRGLPGLPGVPGMPGPKGPP 580
           G               PPGF G +G      T G PG PGP+GL G PG+ G+PG +G  
Sbjct: 823 GDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGER 882

Query: 581 GPPGPSGAV---VPLALQNEP--------TPAPEDNGCP 608
           G PG +GAV    PL +   P          +P  NG P
Sbjct: 883 GLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAP 921



 Score =  153 bits (386), Expect = 6e-37
 Identities = 81/165 (49%), Positives = 92/165 (55%), Gaps = 12/165 (7%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG------PIGPAGPPGER 496
           G PG +G  G  G  G PG TG +G  GE+G  G PGPAG RG      P+GPAGP G  
Sbjct: 193 GAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSA 252

Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
           G  G  G+ GPKG  G+ G  GP GP+G   P G  G  GL GP GPPG  G  G  G  
Sbjct: 253 GPPGFPGAPGPKGEIGAVGNAGPAGPAG---PRGEVGLPGLSGPVGPPGNPGANGLTGAK 309

Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601
           G  G   LPG+ G PG+PGP+G PGP G +GA     L  EP PA
Sbjct: 310 GAAG---LPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPA 351



 Score =  153 bits (386), Expect = 6e-37
 Identities = 88/183 (48%), Positives = 99/183 (54%), Gaps = 27/183 (14%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQ---KGEKGEPGPPGPAGERG---------PIGPA 490
           G PG  GPRG  GS G  GP G +G     G  G PGP GPAG RG         P GP 
Sbjct: 442 GEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPT 501

Query: 491 GPPGERGGKG------SKGSQGPKGSRGSPGKPGP---QGPSGDPGPPGPPGKEGLPGPQ 541
           G PG+ G KG      ++G+ GP G+ G+ G PGP   QG  G+ GPPGPPG +GLPGP 
Sbjct: 502 GDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPS 561

Query: 542 GP------PGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQ 595
           GP      PG +GL G  G PG  GPRG  G PG  G  GP GP G  GPSG   P   +
Sbjct: 562 GPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNK 621

Query: 596 NEP 598
            EP
Sbjct: 622 GEP 624



 Score =  152 bits (384), Expect = 1e-36
 Identities = 79/152 (51%), Positives = 87/152 (57%), Gaps = 3/152 (1%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPA---GPPGERG 497
           L G  G  GP G+ G+QGPPGP G +G KGE+G PGPPG  G  GP GPA   G PGERG
Sbjct: 515 LAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERG 574

Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557
             G  G  GP G RG  G PG  G +G  GP G  G  G PGP G  G  G+ G VG  G
Sbjct: 575 LHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAG 634

Query: 558 VPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAV 589
             GP GLPG  G  G+PG KG  G PG  G +
Sbjct: 635 PSGPSGLPGERGAAGIPGGKGEKGEPGLRGEI 666



 Score =  151 bits (382), Expect = 2e-36
 Identities = 88/191 (46%), Positives = 95/191 (49%), Gaps = 25/191 (13%)

Query: 442 QGPPGP------RGPRGDRGSQGPPGPTGNKGQKGEKGEPGPP------GPAGERGPIGP 489
           QGPPGP      RGP G+ GS GPPGP G +G  G +G PG        GP G RG  GP
Sbjct: 369 QGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGP 428

Query: 490 AGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGL 549
           AG  G  G  G  G  G  G RG PG PG  GP+G  GP G PG +G PGP GP G +G 
Sbjct: 429 AGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGE 488

Query: 550 QGTVGEPGVPGPRGLP---------GLPGVPGMPGP---KGPPGPPGPSGAVVPLALQNE 597
            G +G PG  GP G P         GL G  G PGP    G  GPPGP G       Q  
Sbjct: 489 PGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGP 548

Query: 598 PTPAPEDNGCP 608
           P P P   G P
Sbjct: 549 PGP-PGFQGLP 558



 Score =  150 bits (380), Expect = 3e-36
 Identities = 79/157 (50%), Positives = 85/157 (54%), Gaps = 9/157 (5%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
           + GP G  G  G RG  G PGP G+KG+ G KGEPG  GP G  GP G  G  G  G  G
Sbjct: 329 IPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAG 388

Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPG 560
           S G  GP G RGSPG  G  G  G  G  GPPG  G  GP G  G  G  G  GEPG+ G
Sbjct: 389 SAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMG 448

Query: 561 PRGLPGLP---------GVPGMPGPKGPPGPPGPSGA 588
           PRGLPG P         G  G+PG  G PGP GP+GA
Sbjct: 449 PRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGA 485



 Score =  150 bits (379), Expect = 4e-36
 Identities = 85/180 (47%), Positives = 94/180 (52%), Gaps = 30/180 (16%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---------PAGP 492
           +G  GP G RG  G  G PG  G  G +G  G PG  GPAG+ GP+G         P GP
Sbjct: 423 RGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGP 482

Query: 493 PGERGGKGSKGSQGPKGSRGSPGK---------------PGPQGPSGDPGPPGPPGKE-- 535
            G RG  G+ G  GPKG  G PGK               PGP G +G  GPPGP G +  
Sbjct: 483 AGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGG 542

Query: 536 -GLPGPQGPPGFQGL---QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
            G  GP GPPGFQGL    G  GE G PG RGL G  G+PG  GP+G  GPPG SGA  P
Sbjct: 543 KGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGP 602



 Score =  150 bits (379), Expect = 4e-36
 Identities = 79/156 (50%), Positives = 88/156 (56%), Gaps = 6/156 (3%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKG------QKGEKGEPGPPGPAGERGPIGPAGPPGE 495
           QGPPGP+G +G +G QGPPGP G +G        GE G+PG  G  GE G  GPAGP GE
Sbjct: 531 QGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGE 590

Query: 496 RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGE 555
           RG  G  G+ GP G  GS G  GP GP G+ G PG  G  G  GP GP G  G +G  G 
Sbjct: 591 RGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGI 650

Query: 556 PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
           PG  G +G PGL G  G PG  G  G PG  GA  P
Sbjct: 651 PGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGP 686



 Score =  149 bits (377), Expect = 7e-36
 Identities = 86/209 (41%), Positives = 99/209 (47%), Gaps = 40/209 (19%)

Query: 433 QLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG---------- 482
           Q ++  T+ +GP G RGPRG+RG  GPPG  G  G  G  G PGPPGP G          
Sbjct: 23  QSLQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYD 82

Query: 483 ---------ERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP-- 531
                      G +GP GPPG  G  G +G QGP G  G PG+ GP G  G  GPPG   
Sbjct: 83  GKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAG 142

Query: 532 ----PGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGL------------PGLPGV---PG 572
               PGK G PG +G  G QG +G  G PG+PG +G+            PG PGV   PG
Sbjct: 143 EDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPG 202

Query: 573 MPGPKGPPGPPGPSGAVVPLALQNEPTPA 601
            PG  G PG  G  G          P PA
Sbjct: 203 APGENGTPGQTGARGLPGERGRVGAPGPA 231



 Score =  148 bits (374), Expect = 2e-35
 Identities = 78/154 (50%), Positives = 86/154 (55%), Gaps = 9/154 (5%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGE------RGPIGPAGPPGER 496
           G PGP G RG  GS GP GP G  G  G  G PG PGP GE       GP GPAGP GE 
Sbjct: 226 GAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEV 285

Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDP---GPPGPPGKEGLPGPQGPPGFQGLQGTV 553
           G  G  G  GP G+ G+ G  G +G +G P   G PG PG  G+PGP G  G  G +G V
Sbjct: 286 GLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLV 345

Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
           GEPG  G +G  G  G PG  GP+GPPGP G  G
Sbjct: 346 GEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEG 379



 Score =  148 bits (374), Expect = 2e-35
 Identities = 78/169 (46%), Positives = 91/169 (53%), Gaps = 24/169 (14%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            G PGP G  G  G++GPPG  G+ G  G  GE G  G  G  GP G  G PG +G +G  
Sbjct: 892  GEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYP 951

Query: 503  GSQGPKGSRGSPGKPGPQGPSG------DPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
            G+ GP G+ G+PG  GP GP+G      + GP GP G  G  GP+GP G QG++G  GEP
Sbjct: 952  GNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEP 1011

Query: 557  GVPGPRGLPGL------------------PGVPGMPGPKGPPGPPGPSG 587
            G  GPRGLPGL                   G PG  GP GP GP GPSG
Sbjct: 1012 GEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSG 1060



 Score =  148 bits (373), Expect = 2e-35
 Identities = 75/155 (48%), Positives = 83/155 (53%), Gaps = 9/155 (5%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
            +G PG  GP G  G+ GP GP G  G+ G +GE GP GP G  G +GP GP G +G +G 
Sbjct: 948  RGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGD 1007

Query: 502  KGSQGPKGSRGSP---------GKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552
            KG  G KG RG P         G PG  G  GD G PG  G  G  GP GP G  G  G 
Sbjct: 1008 KGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGR 1067

Query: 553  VGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
             G PG  GP G+ G  G  G  GP GPPGPPGP G
Sbjct: 1068 TGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPG 1102



 Score =  147 bits (371), Expect = 3e-35
 Identities = 71/145 (48%), Positives = 79/145 (54%), Gaps = 12/145 (8%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           G PGP G  GDRG  G  GP G  G +G  GE G  GPAG  G  GPAG  G+ G KG +
Sbjct: 682 GAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGER 741

Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
           G++GPKG  G  G  GP G +G  GP GPPG  G  G  GPPG  G  G  G  G PGP 
Sbjct: 742 GAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPS 801

Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSG 587
           G+             GPPGPPGP+G
Sbjct: 802 GI------------SGPPGPPGPAG 814



 Score =  145 bits (366), Expect = 1e-34
 Identities = 82/176 (46%), Positives = 89/176 (50%), Gaps = 12/176 (6%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG---ERGGK 499
           GP G  G RG+ G+ GP GP G +G  GE+GE GP GP G  GP G AG PG   ERG K
Sbjct: 685 GPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAK 744

Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPG------PPGKEGLPGPQGPPGFQGLQGTV 553
           G KG  G  G  G  G  GP GP+G PGP G      PPG  G PG  G  G  G  G  
Sbjct: 745 GPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGIS 804

Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609
           G PG PGP G  GL    G  G +GP G  G  GAV P     E  P+ E     P
Sbjct: 805 GPPGPPGPAGKEGL---RGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGP 857



 Score =  144 bits (364), Expect = 2e-34
 Identities = 88/208 (42%), Positives = 97/208 (46%), Gaps = 34/208 (16%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGE---------RGPIGPAG 491
           L GP GPRG RG  G  G  GPTG  G +G  G PGP G  GE          GP GP+G
Sbjct: 581 LPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSG 640

Query: 492 PPGER------GGKGSKGSQGPKGSRGSPGK------------PGPQGPSGDPGPPGPPG 533
            PGER      GGKG KG  G +G  G+PG+            PGP G +GD G  G  G
Sbjct: 641 LPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAG 700

Query: 534 KEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPP------GPPGPSG 587
             G  GP+G PG +G  G  G  G  GP G  G PG  G  G KGP       GP GP G
Sbjct: 701 PAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVG 760

Query: 588 AVVPLALQNEPTPA-PEDNGCPPHWKNF 614
           A  P      P PA    +G PP    F
Sbjct: 761 AAGPAGPNGPPGPAGSRGDGGPPGMTGF 788



 Score =  144 bits (362), Expect = 4e-34
 Identities = 81/190 (42%), Positives = 94/190 (49%), Gaps = 22/190 (11%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE---------------PGPPGPAGERGP 486
           +G  G  GP G  G+ GP GP G  G  G +G+                GPPGP+G  GP
Sbjct: 747 KGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGP 806

Query: 487 IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF 546
            GP GP G+ G +G +G QGP G  G  G  GP G +G+ GP G  G  G PG  GP G 
Sbjct: 807 PGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGL 866

Query: 547 QGLQGTVGEPGVPGPRGLPGLPGVPGMPGP---KGPPGPPGPSGAVVPLALQNEPTPAPE 603
            G  G +G PG  G RGLPG+ G  G PGP    GPPG  GP GAV    +   P  A  
Sbjct: 867 LGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGR 926

Query: 604 D----NGCPP 609
           D    N  PP
Sbjct: 927 DGNPGNDGPP 936



 Score =  143 bits (360), Expect = 7e-34
 Identities = 76/149 (51%), Positives = 85/149 (57%), Gaps = 9/149 (6%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           GP G  GPRG  G+ G PGP G +G  GE GEPG  GPAG RGP   AGPPG+ G  G  
Sbjct: 91  GPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGP---AGPPGKAGEDGHP 147

Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQ---GLQGTVGEPGVP 559
           G  G  G R   G  GPQG  G PG PG PG +G+ G  G  G +   G  G  GEPG P
Sbjct: 148 GKPGRPGER---GVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAP 204

Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588
           G  G PG  G  G+PG +G  G PGP+GA
Sbjct: 205 GENGTPGQTGARGLPGERGRVGAPGPAGA 233



 Score =  143 bits (360), Expect = 7e-34
 Identities = 86/197 (43%), Positives = 95/197 (48%), Gaps = 45/197 (22%)

Query: 443 GPPGPRGPRGD---RGSQGPPGPTGNKGQKG------------EKGEPGPPGPAGERGPI 487
           GP GP GPRG+    G  GP GP GN G  G              G PG PGP G  GP+
Sbjct: 274 GPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPV 333

Query: 488 G---------------PAGPPGERGGKGSKGS---QGPKGSRGSPGKPGPQGPSGDPGPP 529
           G               PAG  GE G KG  GS   QGP G  G  GK GP G +G  GPP
Sbjct: 334 GAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPP 393

Query: 530 GPPGKEGLPGPQGPPGFQGLQGTVGEP---------GVPGPRGLPGLPGVPGMPGPKGPP 580
           GPPG  G PG +G PG  G  G +G P         GV GP G  G PG PG+ GP+G P
Sbjct: 394 GPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLP 453

Query: 581 GPP---GPSGAVVPLAL 594
           G P   GP+G   P+ L
Sbjct: 454 GSPGNIGPAGKEGPVGL 470



 Score =  142 bits (359), Expect = 9e-34
 Identities = 71/150 (47%), Positives = 85/150 (56%), Gaps = 6/150 (4%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG---PPGPAGERGPIGPAGPPGERG 497
            + G PG  G  G+ G+ GPPG  G  G KGE+G PG   P G AG  GP GP GP G+ G
Sbjct: 917  VNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHG 976

Query: 498  GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557
             +G  G  GP G  G+ G  GP GP G  G  G PG++   GP+G PG +G  G  G PG
Sbjct: 977  NRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEK---GPRGLPGLKGHNGLQGLPG 1033

Query: 558  VPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
            + G  G  G PG  G  GP+GP GP GP+G
Sbjct: 1034 IAGHHGDQGAPGSVGPAGPRGPAGPSGPAG 1063



 Score =  142 bits (357), Expect = 1e-33
 Identities = 79/169 (46%), Positives = 89/169 (52%), Gaps = 18/169 (10%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP---IGPAGPPGERG 497
           + GPPGP GP G  G +GP G  G  G+ GE G  GPPG AGE+GP    G AGPPG  G
Sbjct: 803 ISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPG 862

Query: 498 GKG------------SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPG 545
            +G            S+G +G  G  G+ G+PGP G +G PG  GPPG  G PG  G PG
Sbjct: 863 PQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPG 922

Query: 546 FQGLQGTVGEPGVPGPRGLPGLPGVPGMP---GPKGPPGPPGPSGAVVP 591
             G  G  G  G PG  G PG  G  G P   GP G  G PGP G V P
Sbjct: 923 EAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGP 971



 Score =  141 bits (355), Expect = 2e-33
 Identities = 76/161 (47%), Positives = 85/161 (52%), Gaps = 15/161 (9%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGER---------GPIGPAGPP 493
           GP GP GP G  G  G PG  G KG+ G  G  GP GPAG R         GP+GP G P
Sbjct: 241 GPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNP 300

Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553
           G  G  G+KG+ G  G  G+PG PGP+G  G  G  G  G  GL G  GP G +G  G  
Sbjct: 301 GANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNK 360

Query: 554 GEPGVPGPRGLPGLPGVPGMPGPK------GPPGPPGPSGA 588
           GEPG  GP+G PG  G  G  GP       GPPGPPG  G+
Sbjct: 361 GEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGS 401



 Score =  141 bits (355), Expect = 2e-33
 Identities = 76/166 (45%), Positives = 85/166 (51%), Gaps = 9/166 (5%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE---PGPPGPAGERGP------IGPAGP 492
           QGPPGP G +G  G  GP G  G  G++G  GE   PGP GP GERGP       GP GP
Sbjct: 546 QGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGP 605

Query: 493 PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552
            G RG  G  G  G KG  G  G  G  GPSG  G PG  G  G+PG +G  G  GL+G 
Sbjct: 606 IGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGE 665

Query: 553 VGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598
           +G PG  G RG PG  G PG  G  G  G  G +G   P   +  P
Sbjct: 666 IGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSP 711



 Score =  140 bits (354), Expect = 3e-33
 Identities = 79/170 (46%), Positives = 92/170 (54%), Gaps = 10/170 (5%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG------PPGPAGERGPIGPAGPPGER 496
           GP G RG  G+ G  GP GPTG+ G+ G+KG  G       PGP G  G  GP GP G +
Sbjct: 481 GPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQ 540

Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
           GGKG +G  GP G +G PG  GP G  G PG  G  G+ GLPGP GP   +G +G  GE 
Sbjct: 541 GGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGP---RGERGPPGES 597

Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNG 606
           G  GP G  G  G  G PGP G  G PG  GA V  A  + P+  P + G
Sbjct: 598 GAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGA-VGTAGPSGPSGLPGERG 646



 Score =  139 bits (351), Expect = 7e-33
 Identities = 74/162 (45%), Positives = 82/162 (50%), Gaps = 3/162 (1%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           G PG RG  G+ G  GP GP G +G  GE G  GP GP G RGP GP GP G +G  G  
Sbjct: 568 GKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVV 627

Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
           G+ G  G  G  G PG +G +G PG  G  G+ GL G  G PG  G +G  G  G PGP 
Sbjct: 628 GAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPA 687

Query: 563 GLPGLPGVPGMPGPKGPPGP---PGPSGAVVPLALQNEPTPA 601
           G  G  G  G  GP GP GP   PG  G V P        PA
Sbjct: 688 GATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPA 729



 Score =  139 bits (349), Expect = 1e-32
 Identities = 75/164 (45%), Positives = 90/164 (54%), Gaps = 21/164 (12%)

Query: 443 GPPG---PRGPRGDRGSQGPPGPTGNKG------------QKGEKGEPGPPGPAGERGPI 487
           GPPG    +GP G+ G+ GPPG  G +G             +GE+G PG  G  GE GP+
Sbjct: 838 GPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPL 897

Query: 488 GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQ 547
           G AGPPG RG  G+ GS G  G+      PG  G  G+PG  GPPG++G PG +G  G+ 
Sbjct: 898 GIAGPPGARGPPGAVGSPGVNGA------PGEAGRDGNPGNDGPPGRDGQPGHKGERGYP 951

Query: 548 GLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
           G  G VG  G PGP G  G  G  G  G  GP GP GP+GAV P
Sbjct: 952 GNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGP 995



 Score =  136 bits (343), Expect = 6e-32
 Identities = 74/167 (44%), Positives = 83/167 (49%), Gaps = 21/167 (12%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
           G  GP GP G  G  GPPGP G +G +G +G+ GP G  GE G +GP G  GE+G  G  
Sbjct: 793 GRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEA 852

Query: 503 GSQGP------------------KGSRGSPGKPGPQGPSGDPGP---PGPPGKEGLPGPQ 541
           G+ GP                   GSRG  G PG  G  G+PGP    GPPG  G PG  
Sbjct: 853 GTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAV 912

Query: 542 GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588
           G PG  G  G  G  G PG  G PG  G PG  G +G PG  GP GA
Sbjct: 913 GSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGA 959



 Score =  135 bits (340), Expect = 1e-31
 Identities = 78/172 (45%), Positives = 87/172 (50%), Gaps = 24/172 (13%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGP------AGPPGE 495
           QGP G  G  G  G  G  GP G  G+ GE G PG PG  GERG +GP       G PG 
Sbjct: 114 QGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGL 173

Query: 496 RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGK---EGLPGPQ------GPPGF 546
            G KG +G  G  G +G PG PG +G  G PG  G PG+    GLPG +      GP G 
Sbjct: 174 PGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGA 233

Query: 547 QGLQGTVGEPGVPGPRGLPGLPGVPGMPGPK---------GPPGPPGPSGAV 589
           +G  G+VG  G  GP G  G PG PG PGPK         GP GP GP G V
Sbjct: 234 RGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEV 285



 Score =  132 bits (331), Expect = 2e-30
 Identities = 75/171 (43%), Positives = 85/171 (49%), Gaps = 12/171 (7%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
           +GPPG  G  G +G QGP G  G  GQ G  G  GP GP G+ G  G  G PG  G +G 
Sbjct: 99  RGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGV 158

Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGP 561
            G QG +G  G+PG PG +G  G  G  G  G+ G PG +G PG  G  GT   PG  G 
Sbjct: 159 VGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGT---PGQTGA 215

Query: 562 RGLPGLPGVPGMPGPK---------GPPGPPGPSGAVVPLALQNEPTPAPE 603
           RGLPG  G  G PGP          GP GP GP G+  P      P P  E
Sbjct: 216 RGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGE 266



 Score =  107 bits (267), Expect = 4e-23
 Identities = 56/122 (45%), Positives = 66/122 (54%), Gaps = 18/122 (14%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKG---------------EKGEPGPPGPAGERGP 486
            +GP GP+G RGD+G  G  GP G  G KG               ++G PG  GPAG RGP
Sbjct: 996  RGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGP 1055

Query: 487  IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF 546
             GP+GP G+ G  G  G+ GP G RG  G  GP GP   PGPPGPPG  G+ G     G+
Sbjct: 1056 AGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGP---PGPPGPPGPPGVSGGGYDFGY 1112

Query: 547  QG 548
             G
Sbjct: 1113 DG 1114



 Score = 88.2 bits (217), Expect = 3e-17
 Identities = 46/102 (45%), Positives = 52/102 (50%), Gaps = 18/102 (17%)

Query: 435  IKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG 494
            +K    LQG PG  G  GD+G+ G  G                  PAG RGP GP+GP G
Sbjct: 1022 LKGHNGLQGLPGIAGHHGDQGAPGSVG------------------PAGPRGPAGPSGPAG 1063

Query: 495  ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG 536
            + G  G  G+ GP G RG  G  GP GP G PGPPGPPG  G
Sbjct: 1064 KDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSG 1105



 Score = 87.8 bits (216), Expect = 3e-17
 Identities = 50/113 (44%), Positives = 55/113 (48%), Gaps = 7/113 (6%)

Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQ----GLQGTVG 554
           KG  G +GP+G RG PG PG  G  G  GPPGPPG  G PG  G    Q    G+    G
Sbjct: 32  KGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPG 91

Query: 555 EPGVPGPRGLPGLPGVPG---MPGPKGPPGPPGPSGAVVPLALQNEPTPAPED 604
             G+ GPRG PG  G PG     GP G PG PG +G          P  A ED
Sbjct: 92  PMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGED 144



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 16/36 (44%), Positives = 20/36 (55%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG 476
            ++GP G +GP G  G  GPPGP G  G   + G  G
Sbjct: 1079 IRGPQGHQGPAGPPGPPGPPGPPGVSGGGYDFGYDG 1114


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score =  161 bits (407), Expect = 2e-39
 Identities = 80/154 (51%), Positives = 92/154 (59%), Gaps = 3/154 (1%)

Query: 438  FTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERG 497
            F  L G PG  G +GDRG  GPPG     G KG  G PG PG  G  G  GP GPPG RG
Sbjct: 998  FIGLVGEPGIVGEKGDRGMMGPPGV---PGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRG 1054

Query: 498  GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557
              G +G++G +G RG  G  G QG  G  GPPGP G+ G PG QG  G +G  G+ G PG
Sbjct: 1055 PPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPG 1114

Query: 558  VPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
            +PGP G PG  G+PG PGP+GP GP GP G + P
Sbjct: 1115 IPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGP 1148



 Score =  154 bits (389), Expect = 3e-37
 Identities = 90/214 (42%), Positives = 102/214 (47%), Gaps = 54/214 (25%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQ---------------KGEKGEPGPPGPAGERG 485
            L GP G  GP GD G  GPPG  G +GQ               KGE G+PG PGP GE+G
Sbjct: 935  LPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQG 994

Query: 486  PIG------------------PAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPG 527
             +G                    GPPG  G KGS G  G  G  G+PG+PGPQGP G  G
Sbjct: 995  FMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRG 1054

Query: 528  PPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPG---------------VPG 572
            PPG  G +G  GP+GP G  G QG+ G  G PGP+G PG PG                PG
Sbjct: 1055 PPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPG 1114

Query: 573  MPGPKGP------PGPPGPSGAVVPLALQNEPTP 600
            +PGP GP      PG PGP G   P+    E  P
Sbjct: 1115 IPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGP 1148



 Score =  152 bits (383), Expect = 1e-36
 Identities = 75/152 (49%), Positives = 91/152 (59%), Gaps = 6/152 (3%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGPPGERGG 498
            +GPPG RG +G RG +GP GP G +G +G KG PGP   PG  G++G  G  G  G RG 
Sbjct: 1053 RGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGF 1112

Query: 499  KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF---QGLQGTVGE 555
             G  G  GP G++G PG+PGPQGP G  GPPG  G +G PG  G PG     G++G +G 
Sbjct: 1113 PGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGP 1172

Query: 556  PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
             G PG +GL G  G PG+ G  GP GP G  G
Sbjct: 1173 LGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKG 1204



 Score =  152 bits (383), Expect = 1e-36
 Identities = 77/154 (50%), Positives = 93/154 (60%), Gaps = 9/154 (5%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            GPPG RGP GDRG +G PG  G  GQ+G +G  G PG  G+ G  GP G PG +G KG++
Sbjct: 1343 GPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAE 1402

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF---------QGLQGTV 553
            G +G +G  G+PG+ G QG  G PGP G  G++GL G  GP G          QG QG  
Sbjct: 1403 GPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDD 1462

Query: 554  GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
            G+PG  GP G  G PGV G+PG +GPPG  G SG
Sbjct: 1463 GDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESG 1496



 Score =  151 bits (381), Expect = 2e-36
 Identities = 75/159 (47%), Positives = 92/159 (57%), Gaps = 12/159 (7%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG---PPGPAGERGPIGPAGPPGERG 497
            + GPPG  GP+G  G  G PG  G  G+ G +G PG   PPG  G +G  GP GP G  G
Sbjct: 1016 MMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAG 1075

Query: 498  GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGL-------- 549
             +GS+G +GP G +G PG+PG QG +G+ G  G  G  G+PGP GPPG +GL        
Sbjct: 1076 EQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQG 1135

Query: 550  -QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
             QG +G PG  GP+G PG  G PG+PG  G  G  GP G
Sbjct: 1136 PQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLG 1174



 Score =  150 bits (379), Expect = 4e-36
 Identities = 83/178 (46%), Positives = 96/178 (53%), Gaps = 15/178 (8%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGE---KGEPGPPGPAGERGPIGPAGPPGERGG 498
            QGP GP GP G+ G +GPPG  G  G  GE   KG+ GP G  GE+G IG  G PG  G 
Sbjct: 1134 QGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGD 1193

Query: 499  KGSKGSQGPKGSRGSPG------KPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552
             G  G  G KG RG PG      + G +G  G+ GPPGPPG  G+ GP+G  G QG +G 
Sbjct: 1194 SGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGR 1253

Query: 553  VGEPGVP------GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPED 604
             G  G        G  G+PG PG PG PGPKG  G  GP+GA   +  Q EP  A  D
Sbjct: 1254 TGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYD 1311



 Score =  149 bits (377), Expect = 7e-36
 Identities = 81/167 (48%), Positives = 92/167 (55%), Gaps = 17/167 (10%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            GP GP G RG+ G  G PG  G  G KGE G PG  GP G+RG  G  G PG +G  GSK
Sbjct: 1466 GPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSK 1525

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
            G  G  G  G PG  G  GP G   PPG  G +G+ GP+GPPG  G +G VG  G+ GP 
Sbjct: 1526 GQPGDSGEMGFPGMAGLFGPKG---PPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPS 1582

Query: 563  GLP------------GLPGVPGMPGPKGPPGPPGPSGAVVPLALQNE 597
            GLP            GL G  G PGP+G PGPPGP G   P+ LQ +
Sbjct: 1583 GLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGG--PIQLQQD 1627



 Score =  149 bits (376), Expect = 9e-36
 Identities = 84/180 (46%), Positives = 100/180 (55%), Gaps = 19/180 (10%)

Query: 443  GPPGPRGPRGDRGSQGPPG---PTGNKGQKGEKGEPGPPGPAGE------RGPIGPAGPP 493
            G PG  G  G+ G QGPPG   P G +G KG +G  GP GPAGE      +GP GP G P
Sbjct: 1033 GMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRP 1092

Query: 494  GERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQ--- 550
            G  G +G  G +G  GSRG PG PGP GP G  G PG PG +G  GP GPPG  G +   
Sbjct: 1093 GRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPP 1152

Query: 551  GTVGEPGVPGPRGLP------GLPGVPGMPGPKGPPGPPGPSGAVVPLALQNE-PTPAPE 603
            G VGEPG+PG  G+       G PG  G+ G +G PG  G SG + P  L+ +   P P+
Sbjct: 1153 GAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPD 1212



 Score =  149 bits (375), Expect = 1e-35
 Identities = 80/169 (47%), Positives = 91/169 (53%), Gaps = 16/169 (9%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            GP GP G +GDRG  GP G  G KGQ+G  GE GPPGP G  G     GP G+ G +G K
Sbjct: 1195 GPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGV---RGPEGKSGKQGEK 1251

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562
            G  G KG++G  G+ G  G  GDPGPPG PG +G  G  GP G  G  G  GEPG+ G  
Sbjct: 1252 GRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYD 1311

Query: 563  GLPGLPGVPGMPGPK-------------GPPGPPGPSGAVVPLALQNEP 598
            G  G+ G  G PGPK             GPPGPPG  G V     + EP
Sbjct: 1312 GHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEP 1360



 Score =  148 bits (373), Expect = 2e-35
 Identities = 77/157 (49%), Positives = 90/157 (57%), Gaps = 12/157 (7%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            G PGP GP G  G  GPPG  G +G KG+ G  G PGP G+ GP G  GP G  G  G +
Sbjct: 901  GFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLE 960

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKE------GLPGPQGPPGFQGLQGTVGEP 556
            G  G KG  G PG  G +G  GDPG PGP G++      GL G  G  G +G +G +G P
Sbjct: 961  GQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPP 1020

Query: 557  GVPGPR------GLPGLPGVPGMPGPKGPPGPPGPSG 587
            GVPGP+      G+PG  G PG PGP+GPPG  GP G
Sbjct: 1021 GVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPG 1057



 Score =  146 bits (369), Expect = 6e-35
 Identities = 82/190 (43%), Positives = 97/190 (51%), Gaps = 25/190 (13%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPA---GPPGERGG 498
            QG  G +G  G  G++G PGP G  G KG  G PGPPGP G  G IGP    GP G +G 
Sbjct: 870  QGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGK 929

Query: 499  KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL------------------PGP 540
             G++G  GP+G  G  G  GP GP G PG  G PG++G                   PGP
Sbjct: 930  PGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGP 989

Query: 541  QGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP 600
             G  GF G  G VGEPG+ G +G  G+ G PG+PGPKG  G PG  G    +    EP P
Sbjct: 990  VGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGG---MGTPGEPGP 1046

Query: 601  -APEDNGCPP 609
              P  +  PP
Sbjct: 1047 QGPPGSRGPP 1056



 Score =  146 bits (368), Expect = 8e-35
 Identities = 82/168 (48%), Positives = 96/168 (57%), Gaps = 21/168 (12%)

Query: 438 FTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERG 497
           F +L GPP   GP+GD G  GPPG  G  G  G +G  GPPGP G  G  GP G  G++G
Sbjct: 620 FPLLMGPP---GPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKG 676

Query: 498 ------GK---GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF-- 546
                 GK   G+KG  G  G  G+PG PG +G  G PGP G PG++G PGP+G PG   
Sbjct: 677 DPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKG 736

Query: 547 ----QGLQGTVGEPGVPGPR---GLPGLPGVPGMPGPKGPPGPPGPSG 587
               QGL G VG+PG  G R   GLPGL G+PG  G +G PG PG  G
Sbjct: 737 YPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRG 784



 Score =  145 bits (367), Expect = 1e-34
 Identities = 85/181 (46%), Positives = 94/181 (51%), Gaps = 18/181 (9%)

Query: 441 LQGPPGPRGPRGDRGSQGP---PGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERG 497
           L GPPG  G  GD G  GP   PGP G KG  G  GEPG  G  GE+G  G +G PG +G
Sbjct: 812 LPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQG 871

Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557
            KGS+G  G  G+RG PG  G  G  G  G PGPPG EG PG  GPPG  G +G  G+PG
Sbjct: 872 DKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPG 931

Query: 558 ---VPGPRGL------------PGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAP 602
              +PGPRG             PG PG+ G PG KG PG PG  G          P P  
Sbjct: 932 ARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVG 991

Query: 603 E 603
           E
Sbjct: 992 E 992



 Score =  144 bits (362), Expect = 4e-34
 Identities = 80/164 (48%), Positives = 92/164 (56%), Gaps = 6/164 (3%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG-PPGPA--GERGPIGPAGPPGERG 497
           L G PG RGPRG  G  G PG  G  G KG+KG+PG  PG A  G +G +G  G  G  G
Sbjct: 644 LPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPG 703

Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP- 556
             G KG +G  G  G PG+ G  GP G PG  G PG++GLPGP G PG +G +G +G P 
Sbjct: 704 PPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPG 763

Query: 557 --GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598
             G+PG  G  GLPGVPG  G  G PG PG  G   P  L   P
Sbjct: 764 LFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNP 807



 Score =  142 bits (359), Expect = 9e-34
 Identities = 80/168 (47%), Positives = 91/168 (54%), Gaps = 27/168 (16%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGE---------------------KGEPGPPG 479
           + G  GPRGP G  G+ G PGP G KGQKG+                      G PGPPG
Sbjct: 647 IPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPG 706

Query: 480 PAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPG 539
             G +G  GPAG PGE+G  G +GS G KG    PG+ G  GP GDPGP G  G  GLPG
Sbjct: 707 RKGHKGYPGPAGHPGEQGQPGPEGSPGAKGY---PGRQGLPGPVGDPGPKGSRGYIGLPG 763

Query: 540 PQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
             G PG  G +G    PGVPG RG  G+PG PG+ G +GPPG  G  G
Sbjct: 764 LFGLPGSDGERGL---PGVPGKRGKMGMPGFPGVFGERGPPGLDGNPG 808



 Score =  141 bits (355), Expect = 2e-33
 Identities = 85/199 (42%), Positives = 98/199 (49%), Gaps = 29/199 (14%)

Query: 428  DSKHGQLIKNFTILQ-GPPGP------RGPRGDRGSQGPPGPTGNKGQKG------EKGE 474
            D +HG+  +   + + GPPGP      RGP G  G QG  G TG KG KG      E G 
Sbjct: 1212 DGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGV 1271

Query: 475  P------GPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD--- 525
            P      G PGP G RG +GP G PG  G +G  G  G  G +G  G  GP GP G+   
Sbjct: 1272 PGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGE 1331

Query: 526  -------PGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKG 578
                    GPPGPPG  G  G +G  G  G  G  G+ GV G RG PG  G PG PGP+G
Sbjct: 1332 QGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRG 1391

Query: 579  PPGPPGPSGAVVPLALQNE 597
             PGP G  GA  P   Q +
Sbjct: 1392 WPGPKGSKGAEGPKGKQGK 1410



 Score =  140 bits (354), Expect = 3e-33
 Identities = 74/160 (46%), Positives = 89/160 (55%), Gaps = 9/160 (5%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGER---GPIGPAGPPGERG 497
            L+GPPGP+G  G  G QG  G  G+ G +G  G PGP GP G +   G  GP GP G  G
Sbjct: 1082 LKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIG 1141

Query: 498  GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557
              G  G +GP G+ G PG PG  G  GD GP G PG++GL G +G PG +G  G +G  G
Sbjct: 1142 PPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDG 1201

Query: 558  V------PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
            +      PGP G  G  G  G+ G  GPPGPPG +G   P
Sbjct: 1202 LKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGP 1241



 Score =  140 bits (353), Expect = 4e-33
 Identities = 76/159 (47%), Positives = 88/159 (55%), Gaps = 12/159 (7%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
            L+G PG +G  G  G +G PGP G+KG +G KG+ G  G  G RG  G  G PG RG  G
Sbjct: 1374 LRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVG 1433

Query: 501  SKGSQGPKGSRGSPGK------PGPQGPSGDPGPPGP------PGKEGLPGPQGPPGFQG 548
             +G +G  G  G PG+       G QG  GDPGP GP      PG  GLPG QGPPGF+G
Sbjct: 1434 RQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKG 1493

Query: 549  LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
              G  G+ G PG RG  G  G+PG  G  G  G PG SG
Sbjct: 1494 ESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSG 1532



 Score =  139 bits (351), Expect = 7e-33
 Identities = 75/166 (45%), Positives = 89/166 (53%), Gaps = 7/166 (4%)

Query: 442  QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE-------PGPPGPAGERGPIGPAGPPG 494
            QG PG  G  G +G  GP GP G KG+KGE+GE       PGPPG  G  G  G  G PG
Sbjct: 1302 QGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPG 1361

Query: 495  ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVG 554
            + G  G +G QG +G  G  G+PG  GP G PGP G  G EG  G QG  G  G +G  G
Sbjct: 1362 DPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQG 1421

Query: 555  EPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP 600
              G+PGPRG+ G  G+ G+ GP G PG  G +G         +P P
Sbjct: 1422 LQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGP 1467



 Score =  137 bits (344), Expect = 5e-32
 Identities = 77/178 (43%), Positives = 90/178 (50%), Gaps = 27/178 (15%)

Query: 441 LQGPPGPRGPRGDRG------SQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG 494
           L G PG RG  G  G       +GPPG  GN G+ G  G PG PG  G+ G +GP G PG
Sbjct: 776 LPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPG 835

Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDP---------GPPGPPGKEGLPGP----- 540
            +G KG  GS G  G +G  G+ G  G SGDP         G PG PG  G PGP     
Sbjct: 836 PKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVG 895

Query: 541 -------QGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
                   GPPG +G  G +G PG  GP G+ G PG  G+PGP+G  GP G  G + P
Sbjct: 896 DKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGP 953



 Score =  135 bits (340), Expect = 1e-31
 Identities = 75/155 (48%), Positives = 86/155 (55%), Gaps = 9/155 (5%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGP---PGE 495
           +G PGP G  G++G  GP G  G KG  G +G PGP   PGP G RG IG  G    PG 
Sbjct: 711 KGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGS 770

Query: 496 RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGE 555
            G +G  G  G +G  G PG PG  G  G PG  G PG+ GLPGP G PG  G  G +G 
Sbjct: 771 DGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGP 830

Query: 556 PGVPGPRGLPGL---PGVPGMPGPKGPPGPPGPSG 587
            G PGP+G+ GL    G PG+ G KG  G PG SG
Sbjct: 831 IGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSG 865



 Score =  135 bits (340), Expect = 1e-31
 Identities = 87/204 (42%), Positives = 100/204 (49%), Gaps = 35/204 (17%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG-------- 494
            GP G +G  G +G QG  G  G +G +G +G PGP G  G +G  G AGP G        
Sbjct: 1394 GPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQA 1453

Query: 495  ----ERGGKGSKGSQGPKGSRGSP---GKPGPQGP------SGDPGPPGPPGKE------ 535
                E+G  G  G  GP G RG+P   G PG QGP      SG PG  GPPGK       
Sbjct: 1454 GQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRT 1513

Query: 536  GLPGPQGPPGFQGLQGTVGEPGVP------GPRGLPGLPGVPGMPGPKGPPGPPGPSGAV 589
            GLPG QG PG +G  G  GE G P      GP+G PG  G  G+ GP+GPPG  G  G V
Sbjct: 1514 GLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIV 1573

Query: 590  VPLA-LQNEPTPAPE-DNGCPPHW 611
             PL  L     P P+ D G    W
Sbjct: 1574 GPLGILGPSGLPGPKGDKGSRGDW 1597



 Score =  132 bits (333), Expect = 9e-31
 Identities = 82/185 (44%), Positives = 90/185 (48%), Gaps = 27/185 (14%)

Query: 441 LQGPPGPRGPRGD------------RGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG 488
           L GPPG +G +GD            +G  G PG +GN G  G KG  G PGPAG  G  G
Sbjct: 665 LPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQG 724

Query: 489 PAGPPGERGGKGSKGSQ---------GPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPG 539
             GP G  G KG  G Q         GPKGSRG  G PG  G  G  G  G PG  G  G
Sbjct: 725 QPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRG 784

Query: 540 PQGPPGFQGLQGTVGEPGV---PGPRGLPGLPGVPGMPGPKGPPGP---PGPSGAVVPLA 593
             G PGF G+ G  G PG+   PG  GLPG PGVPG+ G  G  GP   PGP G    + 
Sbjct: 785 KMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMG 844

Query: 594 LQNEP 598
              EP
Sbjct: 845 SVGEP 849



 Score =  129 bits (325), Expect = 8e-30
 Identities = 76/168 (45%), Positives = 85/168 (50%), Gaps = 21/168 (12%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG------------ERGP-- 486
           L GP G  GP+G RG  G PG  G  G  GE+G PG PG  G            ERGP  
Sbjct: 743 LPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPG 802

Query: 487 -------IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPG 539
                  +G  GPPG  G  G  G  GP G  G  G  G  G  G+PG  G  G++G+PG
Sbjct: 803 LDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPG 862

Query: 540 PQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587
             G PGFQG +G+ G PG PG RG PG  G  G  G  G PGPPGP G
Sbjct: 863 VSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEG 910



 Score =  107 bits (266), Expect = 5e-23
 Identities = 59/126 (46%), Positives = 66/126 (52%), Gaps = 5/126 (3%)

Query: 476 GPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPG-PPGK 534
           GPPGP G+ G  GP G PG  G  G++G +GP G  G+PG PGP G  G  G PG  PGK
Sbjct: 625 GPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGK 684

Query: 535 EGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLAL 594
                  G  G  GL G  G PG PG +G  G PG  G PG +G PGP G  GA      
Sbjct: 685 ----AHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGR 740

Query: 595 QNEPTP 600
           Q  P P
Sbjct: 741 QGLPGP 746



 Score = 79.7 bits (195), Expect = 9e-15
 Identities = 46/103 (44%), Positives = 49/103 (47%), Gaps = 24/103 (23%)

Query: 509 GSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGP------- 561
           GS   P   GP GP GD G PGPPG  GLPG  G  G +G  G  G PG+PGP       
Sbjct: 616 GSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQK 675

Query: 562 -----------------RGLPGLPGVPGMPGPKGPPGPPGPSG 587
                             GLPGL G PG PG KG  G PGP+G
Sbjct: 676 GDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAG 718



 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 44/101 (43%), Positives = 53/101 (52%), Gaps = 21/101 (20%)

Query: 442  QGPPGPRGPRGDRGSQG---------PPGPTGNKGQKGEKGEPGPPGPAGERGPIGP--- 489
            QG PG +G  GD G  G         P GP G+ G KG +G  GPPG  G+ G +GP   
Sbjct: 1519 QGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGI 1578

Query: 490  ---AGPPGERGGKGSKGS------QGPKGSRGSPGKPGPQG 521
               +G PG +G KGS+G       +GP G RG PG PGP G
Sbjct: 1579 LGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPG 1619



 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 64/195 (32%), Positives = 78/195 (40%), Gaps = 51/195 (26%)

Query: 438 FTILQGPPGPRGPRGDRGSQGP----PGPTGNKGQKGEKGEPGP-PGPAGERGPIGP--- 489
           FT L   P P  P   R ++ P    P  +G    +     P P   P G + PIG    
Sbjct: 484 FTALSSSPAPT-PGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEAS 542

Query: 490 --AGPPGE-------RGGKGSKGSQ-GPKGSRGSPGKPGP-------------QGPSGDP 526
             AGP          R GK ++        +R SP +P P             Q  S  P
Sbjct: 543 KKAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSP 602

Query: 527 GPPGP-------PGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGP 579
            P           G    P   GPPG +G      + G+PGP GLPGLPG+PG  GP+GP
Sbjct: 603 RPTSSGYSIFHLAGSTPFPLLMGPPGPKG------DCGLPGPPGLPGLPGIPGARGPRGP 656

Query: 580 PGP------PGPSGA 588
           PGP      PGP GA
Sbjct: 657 PGPYGNPGLPGPPGA 671


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  160 bits (406), Expect = 3e-39
 Identities = 91/195 (46%), Positives = 103/195 (52%), Gaps = 28/195 (14%)

Query: 438  FTILQGPPGP--------RGPRGDRGSQGPPG---PTGNKGQKGEKGEPGPPGPAGERGP 486
            F  +QGPPGP         GP+G+ G QGPPG   PTG +G  G +G PG PG  G +G 
Sbjct: 1230 FPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGE 1289

Query: 487  IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF 546
             G  G PG  G  G KG QGP G +G+PG+PG  G  GDPG PG PG  G+ GP G PG 
Sbjct: 1290 KGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGS 1349

Query: 547  QGLQGTVGEPGVPGPRGLP-------------GLPGVPGMPGPKGPPGPPGPSGAVVPLA 593
             G +G  G  G PGP GLP             G PG+PG PG KG PGP GP G   P  
Sbjct: 1350 AGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTG 1409

Query: 594  LQNEPTPAPEDNGCP 608
                P   P  NG P
Sbjct: 1410 ----PPGDPGRNGLP 1420



 Score =  157 bits (396), Expect = 4e-38
 Identities = 85/173 (49%), Positives = 95/173 (54%), Gaps = 14/173 (8%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
           +G PG  G  G  G  GP GP G +GQKG+ G PGPPGP G RGP G  G PG  G  G 
Sbjct: 50  RGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGM 109

Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG---------LQGT 552
            G  G  G +G PG  G +G  G PG PG PG +G PGP G PG +G         L G 
Sbjct: 110 PGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGP 169

Query: 553 VGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDN 605
            G PG PGP G+ GLPG  G+PGP GPPGPPG  G   P  L     P P+ N
Sbjct: 170 KGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGL-----PGPKGN 217



 Score =  155 bits (393), Expect = 1e-37
 Identities = 85/184 (46%), Positives = 99/184 (53%), Gaps = 23/184 (12%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            G PG  GP+G+ G  G PG  G KG  G+ G PG PG  G +G  G  G PG  G  G K
Sbjct: 1074 GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPK 1133

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV--PG 560
            G  GP G+ G PG+PGP G  G PG PGPPG++G PG  G PG  G +G  G+PG   PG
Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG 1193

Query: 561  PRGLPGL------------PGVPGMPGPKGPP---------GPPGPSGAVVPLALQNEPT 599
            P GLPGL            PG PG+PGPKG P         GPPGP G+  P     +  
Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGN 1253

Query: 600  PAPE 603
            P P+
Sbjct: 1254 PGPQ 1257



 Score =  154 bits (388), Expect = 4e-37
 Identities = 87/177 (49%), Positives = 95/177 (53%), Gaps = 15/177 (8%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
            LQG PG  G  G +G  G PG  G  G KG  G PG  GP GE G IGP GPPG  G  G
Sbjct: 1313 LQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSG 1372

Query: 501  S----KGSQGPKGSRGSPGK---PGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553
                 KG  GP G  G PG    PGPQGP G PGP GPPG    PG  G PGF G  G  
Sbjct: 1373 QSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGD---PGRNGLPGFDGAGGRK 1429

Query: 554  GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAV--VPLALQNEPTPAPEDNGCP 608
            G+PG+PG  G  GL G PG  G +GPPGPPG S       +   ++ T AP+   CP
Sbjct: 1430 GDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQ---CP 1483



 Score =  153 bits (387), Expect = 5e-37
 Identities = 87/173 (50%), Positives = 94/173 (54%), Gaps = 14/173 (8%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
           +GPPGPRG +GD G  GPPGP G +G  G  G PG PG  G  G  G  GP G  G  G+
Sbjct: 68  EGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGT 127

Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGK---EGLPGPQG------PPGFQGLQGT 552
           KG +G  GS G PG  GP GP G PG  G PG      LPGP+G      PPG QGL G 
Sbjct: 128 KGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGP 187

Query: 553 VGEP---GVPGPRGLPGLPGVPGMPGPKGPPGP--PGPSGAVVPLALQNEPTP 600
            G P   G PGP GL G PG PG+PGPKG  G    GP G      LQ  P P
Sbjct: 188 TGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 240



 Score =  152 bits (384), Expect = 1e-36
 Identities = 85/177 (48%), Positives = 94/177 (53%), Gaps = 26/177 (14%)

Query: 441  LQGPPGPRGP------------RGDRGSQGPPG---PTGNKGQKGEKGEPGPPGPA---- 481
            + GPPGP GP            +GD G QG PG   PTG KG KGE G PGPPGP     
Sbjct: 900  MMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNL 959

Query: 482  ----GERGPIGPAGPPGERGGKGSKGSQGPKGS---RGSPGKPGPQGPSGDPGPPGPPGK 534
                GE+G  G  G PG  G KG +G  G  G     G PG PGP GP G+PG PG PG 
Sbjct: 960  LGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGL 1019

Query: 535  EGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
             G PG +G  G  G  G  G  G PGP G+PG PG PG+PG KG  G PG S   +P
Sbjct: 1020 IGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLP 1076



 Score =  151 bits (382), Expect = 2e-36
 Identities = 83/173 (47%), Positives = 96/173 (55%), Gaps = 11/173 (6%)

Query: 436  KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGE 495
            K +  L G PG  G  G  G  GPPGP GN G     G+PG  GP G +G IG  G PG 
Sbjct: 981  KGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGL---PGQPGLIGPPGLKGTIGDMGFPGP 1037

Query: 496  RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDP-----GPPGPPGKEGLPGPQGPPGFQGLQ 550
            +G +G  G  G  G  GSPG PG +G  GDP     G PG PG +G PG  G PG  G++
Sbjct: 1038 QGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIK 1097

Query: 551  GTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP---LALQNEPTP 600
            G+VG+PG+PG  G PG  G PG+PG  G PGPPGP G   P     L  EP P
Sbjct: 1098 GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGP 1150



 Score =  150 bits (380), Expect = 3e-36
 Identities = 86/183 (46%), Positives = 94/183 (51%), Gaps = 27/183 (14%)

Query: 443 GPPGPRGPRG--DRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG--PAGPPGERGG 498
           G PGP GP G    G QGPPGP G  G  G+ G  G PG  G+ GP G    GPPGERG 
Sbjct: 805 GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGS 864

Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDP---------GPPGPPGKEGLPGPQGPPGFQGL 549
            G  G+ GP G  GSPG PG  G SG P         GPPGPPG  G+PG  G PG +G 
Sbjct: 865 PGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924

Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGP--------------PGPPGPSGAVVPLALQ 595
            G  G+PG+PGP G  G  G PG+PGP GP              PG PG  G   P   Q
Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQ 984

Query: 596 NEP 598
             P
Sbjct: 985 GLP 987



 Score =  150 bits (379), Expect = 4e-36
 Identities = 89/197 (45%), Positives = 99/197 (50%), Gaps = 45/197 (22%)

Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKG-----EPGPPGPAGERGPIGPA 490
           K F  + GPPG  G  G  G +GPPGP G  G KGE G      PGPPG  G +G +GP 
Sbjct: 715 KGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPK 774

Query: 491 G------PPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPG--PPGPPGKEGLPGPQG 542
           G      PPG  G  G  G  GPKG  G  G+PGP GP G PG    GPPG  G+PGP G
Sbjct: 775 GDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIG 834

Query: 543 PPGFQGLQGTVGEPG-----VPGP---RGLPGLPGVPG---------MPGP--------- 576
            PG  G+ G  G+PG     VPGP   RG PG+PG PG         +PG          
Sbjct: 835 QPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGT 894

Query: 577 ------KGPPGPPGPSG 587
                  GPPGPPGP G
Sbjct: 895 KGEMGMMGPPGPPGPLG 911



 Score =  148 bits (373), Expect = 2e-35
 Identities = 92/209 (44%), Positives = 96/209 (45%), Gaps = 55/209 (26%)

Query: 438 FTILQGPPGPRGPRGDRGSQGP------PGPTGNKGQKGEKGEPGPPGPAGERGPIGPAG 491
           F  LQGPPGP G  G +G  G       PGP GN G  G  G  G PGP G  GPIGP G
Sbjct: 139 FPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPG 198

Query: 492 PPGERGGKGSKGS-----------QGPKGSRGSPGKPGPQGPSG---------------- 524
           PPG  G  G  G            QGPKG +G  G  GP GP G                
Sbjct: 199 PPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKG 258

Query: 525 ------DPGPPGPPGKEGLPGP----------QGPPGFQGLQGTVGEPGVPGPRGLPGLP 568
                 D GPPGPPG  G PGP          QG PG +G  G  GE G PG  GLPG P
Sbjct: 259 DQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDP 318

Query: 569 GVPGMPG------PKGPPGPPGPSGAVVP 591
           G PG PG       KG  GPPGP G V+P
Sbjct: 319 GYPGEPGRDGEKGQKGDTGPPGPPGLVIP 347



 Score =  147 bits (370), Expect = 5e-35
 Identities = 86/172 (50%), Positives = 94/172 (54%), Gaps = 12/172 (6%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQ---KGEKGEPGPPGPAGERGPIGPAGPP--GERG 497
           G PG  G  G  G  G PGP G  G    KGE+G PG PG  G  G IGP GPP  G  G
Sbjct: 570 GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG 629

Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSG----DPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553
             G KG QG  G+ G PG PGP+G  G     PG PG PG  G  G  G PG  GL G  
Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689

Query: 554 GEPGVPGPRGLPGLPGV--PGMPGPKGPPGPPGPSGAV-VPLALQNEPTPAP 602
           G PG+PG +G PG+PG+  PG PGPKG PG PGP GA   P  +  E  P P
Sbjct: 690 GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGP 741



 Score =  147 bits (370), Expect = 5e-35
 Identities = 87/198 (43%), Positives = 103/198 (52%), Gaps = 37/198 (18%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPT-----GNKGQKGEKGEPGPPGPAGERGPIGPAGPPGE 495
            L GP G +G +G+ G  GPPGP      G+KG+KGE G PG PG +G +G  G  G PG+
Sbjct: 933  LPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQ 992

Query: 496  RGGKGSKGSQGPKGSRGSPGKPG---------------------PQGPSGDPGP---PGP 531
             G  G  G  GP G +G+PG PG                     PQG  G PGP   PG 
Sbjct: 993  PGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQ 1052

Query: 532  PGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGP------PGPPGP 585
            PG  GLPG +G  G  G+  ++G PG+PGP+G PGLPG PG PG KG       PG PG 
Sbjct: 1053 PGSPGLPGQKGDKGDPGI-SSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGT 1111

Query: 586  SGAVVPLALQNEP-TPAP 602
             GA     L   P TP P
Sbjct: 1112 PGAKGQPGLPGFPGTPGP 1129



 Score =  145 bits (366), Expect = 1e-34
 Identities = 90/221 (40%), Positives = 102/221 (46%), Gaps = 54/221 (24%)

Query: 441 LQGPPGPR---GPRGDRGSQGP-----PGPTGNKGQKGEKGEPGPPGPAGERGP------ 486
           + GPPGP    G RG +G +GP     PGP G  GQ G  G PGPPGPAG   P      
Sbjct: 392 VMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEIC 451

Query: 487 -IGPAGPPGERGGKGSKGSQGPKGSRG-------SPGKPGPQGPSGDPGPPGPPGKEGLP 538
             GP GPPG  G KG +G QG KG +G         G  GP G  G PG PGPPG  G P
Sbjct: 452 EPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFP 511

Query: 539 GPQ---------GPPGFQGLQGTVGEPGVPGPR----------------------GLPGL 567
           G +         GP G  G+ G  G PG PG +                      G PGL
Sbjct: 512 GQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGL 571

Query: 568 PGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
           PG+PG PG  G PG PGP G    +  + E  P P + G P
Sbjct: 572 PGLPGTPGQDGLPGLPGPKGEPGGITFKGERGP-PGNPGLP 611



 Score =  145 bits (365), Expect = 2e-34
 Identities = 90/194 (46%), Positives = 96/194 (49%), Gaps = 27/194 (13%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
           L G PG +G  G  G  G PGP G KG  G  G PG PG  G  G  GP GPPG  G KG
Sbjct: 691 LPGIPGSKGEPGIPGI-GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG 749

Query: 501 SKGSQ--GPKGSRGSPGKPGPQGPSGD---PGPPGPPGKEGL---------------PGP 540
             G    GP G  G PG  G  GP GD   PGPPGPPG+ GL               PGP
Sbjct: 750 EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGP 809

Query: 541 QGPPGFQGL--QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPG--PPGPSGAVVPLALQN 596
            GPPG  G+  QG  G PG+PGP G PGL G+PG  G  GPPG   PGP G      +  
Sbjct: 810 MGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPG 869

Query: 597 EPTP--APEDNGCP 608
            P P   P   G P
Sbjct: 870 APGPIGPPGSPGLP 883



 Score =  144 bits (364), Expect = 2e-34
 Identities = 84/182 (46%), Positives = 98/182 (53%), Gaps = 42/182 (23%)

Query: 446 GPRGPRGDRGSQGPPGPTGN----------KGQKGEKGEPGPPGPAGERGPIGPAGPPGE 495
           GP+G +G++G QGPPGP G           + QKG++G PG  GP G  G  GP GPPG 
Sbjct: 224 GPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG- 282

Query: 496 RGGKGSKGSQGPKGSRGSPGK------PGPQGPSGDPGPPGPPGKEGL------PGPQGP 543
            G KG KG QG  G RG PGK      PG  G  GDPG PG PG++G        GP GP
Sbjct: 283 -GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGP 341

Query: 544 PGFQ----------GLQGTVGEPGVP---GPRGLPGLPGVPGMPGP-----KGPPGPPGP 585
           PG            G +G +G PG+P   G RG PG+ G PG+PGP      GPPGPPG 
Sbjct: 342 PGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGF 401

Query: 586 SG 587
            G
Sbjct: 402 PG 403



 Score =  143 bits (361), Expect = 5e-34
 Identities = 92/213 (43%), Positives = 104/213 (48%), Gaps = 59/213 (27%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGN-KGQKGEKGEPGP---------------------PG 479
           QG PG RGP G  G +GPPGP G  KG+KGE+GEPG                      PG
Sbjct: 260 QGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPG 319

Query: 480 PAGE---------RGPIGPAGPPG---ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPG 527
             GE         +G  GP GPPG    R G G   + G KG+ G PG PG +G  G PG
Sbjct: 320 YPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGI--TIGEKGNIGLPGLPGEKGERGFPG 377

Query: 528 PPGPPGKEGLP-----GPQGPPGFQGLQGTVGEPG-----VPGPRGLPGLPGVPGMPGPK 577
             GPPG  G P     GP GPPGF G +G  G+ G     +PGP GL G PG PG+PGP 
Sbjct: 378 IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPP 437

Query: 578 GP-------------PGPPGPSGAVVPLALQNE 597
           GP             PGPPGP G+     LQ E
Sbjct: 438 GPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGE 470



 Score =  143 bits (360), Expect = 7e-34
 Identities = 80/156 (51%), Positives = 84/156 (53%), Gaps = 11/156 (7%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPA----GPPGER 496
           L G PG  GP G  G  GPPGP G KG +G  G PG PG  G +G  G      G PG  
Sbjct: 610 LPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLP 668

Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
           G  G  G  G  G  G PG+PG  G  G  G PG PG  GLPGP GP GF G+ G  G P
Sbjct: 669 GNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI-GLPGPPGPKGFPGIPGPPGAP 727

Query: 557 GVPGPRGLPGLPGVPGMPGPKGP-----PGPPGPSG 587
           G PG  GL G PG PG PGPKG      PGPPGP G
Sbjct: 728 GTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPG 763



 Score =  142 bits (359), Expect = 9e-34
 Identities = 82/196 (41%), Positives = 94/196 (47%), Gaps = 29/196 (14%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            G PGP GP+G+ G  G PG  G  G KG  G+ G PGP G  GP GP+G PG+ G  G  
Sbjct: 1000 GLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLP 1059

Query: 503  GSQGPKG-----SRGSPGKPGPQGPSGDPGPPGPPGKEG--------------------- 536
            G +G KG     S G PG PGP+G  G PG PG PG +G                     
Sbjct: 1060 GQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPG 1119

Query: 537  ---LPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLA 593
                PG  GPPG +G+ G  G PG+PG  G  G  G PG PGP G  G PG  G   P  
Sbjct: 1120 LPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG 1179

Query: 594  LQNEPTPAPEDNGCPP 609
             + EP      N  PP
Sbjct: 1180 QKGEPGQPGFGNPGPP 1195



 Score =  141 bits (356), Expect = 2e-33
 Identities = 82/188 (43%), Positives = 94/188 (50%), Gaps = 20/188 (10%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
           + GPPGP+G RG  G  G PG  G  G  G  G PGP G  G  G  G  G PG  G  G
Sbjct: 82  IPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG 141

Query: 501 SKGSQGPKGSRGSPGKPGP------QGPSGDPGPPGPPGKEGLPGPQ------GPPGFQG 548
            +G  GP G  G  G+PG        GP G+PG PGPPG +GLPGP       GPPG  G
Sbjct: 142 LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPG 201

Query: 549 LQGTVGEPGVPGPRGLPGL--PGVPGMPGPKGPPGPPGPSGAV------VPLALQNEPTP 600
           L G  G PG+PGP+G  GL   G  G  G +G  GPPGP G +      + +  Q     
Sbjct: 202 LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261

Query: 601 APEDNGCP 608
            P D G P
Sbjct: 262 LPGDRGPP 269



 Score =  140 bits (353), Expect = 4e-33
 Identities = 82/179 (45%), Positives = 91/179 (50%), Gaps = 34/179 (18%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQK-------GEKGEPGPPGPAGERGPIGPAGPPGE 495
           GPPGP G  GD+G QG  G  G+KG         G  G PG PG  G  GP G  G PG+
Sbjct: 454 GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQ 513

Query: 496 RGGKGSKGSQGPKGSRGSPGKPGP-------------------QGPSGDPGPPGPPGKEG 536
           +G KG  G+ GPKG  G PG PG                    +G  G+ G PG PG  G
Sbjct: 514 KGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573

Query: 537 LPGPQGPPGFQGLQGTVGEPG---VPGPRGLPGLPGVPGMP---GPKGPP--GPPGPSG 587
           LPG  G  G  GL G  GEPG     G RG PG PG+PG+P   GP GPP  GPPGP G
Sbjct: 574 LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVG 632



 Score =  139 bits (350), Expect = 9e-33
 Identities = 81/183 (44%), Positives = 97/183 (53%), Gaps = 25/183 (13%)

Query: 443 GPPGPRGPRGDRGSQ----GPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP------ 492
           G PG  GP+GD G      G PG  GN G+ G+ G PG PG  G+ G  G  G       
Sbjct: 644 GQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGI 703

Query: 493 -----PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG--LPGPQGP-- 543
                PG  G KG  G  GP G+ G+PG+ G +GP G PG PGP G+ G  LPGP GP  
Sbjct: 704 PGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPG 763

Query: 544 -PGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP-----LALQNE 597
            PGF+G  G  G+ G PGP G PG  G+ G+PGPKG  GP G  G + P     + +Q  
Sbjct: 764 LPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGP 823

Query: 598 PTP 600
           P P
Sbjct: 824 PGP 826



 Score =  135 bits (341), Expect = 1e-31
 Identities = 72/140 (51%), Positives = 80/140 (57%), Gaps = 15/140 (10%)

Query: 463 TGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGP 522
           +G KG+KGE+G PG  G  G  G  GP GPPG RG KG  G  GP G +G  G PG  G 
Sbjct: 41  SGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGF 100

Query: 523 SGDPGPPGPPGKEGLPGPQGPPGFQGLQGT---VGEPGVPGPRGLPGLPGVPGM------ 573
            G PG PG PG +G PGPQG PG  G +G     G PG PG +G PG PG+PGM      
Sbjct: 101 PGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGS 160

Query: 574 ------PGPKGPPGPPGPSG 587
                 PGPKG PG PGP G
Sbjct: 161 IIMSSLPGPKGNPGYPGPPG 180



 Score =  134 bits (336), Expect = 4e-31
 Identities = 87/206 (42%), Positives = 101/206 (49%), Gaps = 41/206 (19%)

Query: 443 GPPGPRG---PR-------GDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP--IGPA 490
           GPPGP G   PR       G++G+ G PG  G KG++G  G  GPPG  G  G   +GP 
Sbjct: 337 GPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPP 396

Query: 491 GPPGERGGKGSKGSQGPKG-----------SRGSPGKPGPQGPSG----------DPGPP 529
           GPPG  G +G KG +GP G             G+PG PGP GP+G          +PGPP
Sbjct: 397 GPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPP 456

Query: 530 GPPGKEGLPGPQGPPGFQGLQGTV-------GEPGVPGPRGLPGLPGVPGMPGPKGPPGP 582
           GPPG  G  G QG  G +G +G         G  G PG  GLPGLPG PG  G  G  G 
Sbjct: 457 GPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGE 516

Query: 583 PGPSGAVVPLALQNEPTPAPEDNGCP 608
            G +GA  P  L   P  AP   G P
Sbjct: 517 KGQAGATGPKGLPGIP-GAPGAPGFP 541



 Score =  124 bits (311), Expect = 3e-28
 Identities = 86/230 (37%), Positives = 98/230 (42%), Gaps = 81/230 (35%)

Query: 439 TILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP------PGPAGERGPIGPAGP 492
           T + GPPG  G  G  G  G  G  G KG+KG+ G  GP      PG  G  G  G  G 
Sbjct: 487 TGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGE 546

Query: 493 PGE-------RGGKGSKGSQGPKGSRGSPGKPGPQ------GPSGDP---------GPPG 530
           PG+       +G KG  GS G  G  G PG PG        GP G+P         GPPG
Sbjct: 547 PGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPG 606

Query: 531 PPGKEGLP---GPQGPPGF-----------QGLQGTVGEPGVPGPR-------------- 562
            PG  GLP   GP GPPGF           QG+ G  G+PG+PGP+              
Sbjct: 607 NPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPG 666

Query: 563 -----------------GLPGLPGVPGMPGPKGP--------PGPPGPSG 587
                            GLPG PG+PG+PG KG         PGPPGP G
Sbjct: 667 LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKG 716



 Score =  111 bits (277), Expect = 3e-24
 Identities = 64/152 (42%), Positives = 75/152 (49%), Gaps = 13/152 (8%)

Query: 467 GQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDP 526
           GQ  E        P  +    G  G  GERG  G +G  G  G  G  G PGP+G  GD 
Sbjct: 21  GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80

Query: 527 GPPGPPGKEGLPGPQGPPGFQGLQGTVGEP---GVPGPRGLP---------GLPGVPGMP 574
           G PGPPG +G+ GP G PGF G  G  G P   G PGP+G+P         G PG PG P
Sbjct: 81  GIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP 140

Query: 575 GPKGPPGPPG-PSGAVVPLALQNEPTPAPEDN 605
           G +GPPGPPG P     P ++     P P+ N
Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGN 172



 Score = 80.1 bits (196), Expect = 7e-15
 Identities = 45/106 (42%), Positives = 52/106 (49%), Gaps = 21/106 (19%)

Query: 440  ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499
            I++G  GP G  G  G +G PGP                GP G  GP GP G PG  G  
Sbjct: 1376 IIKGDAGPPGIPGQPGLKGLPGP---------------QGPQGLPGPTGPPGDPGRNGLP 1420

Query: 500  GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPG 545
            G  G+ G KG  G PG+PG +G        GPPG +GL GP GPPG
Sbjct: 1421 GFDGAGGRKGDPGLPGQPGTRGLD------GPPGPDGLQGPPGPPG 1460


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score =  160 bits (405), Expect = 4e-39
 Identities = 89/192 (46%), Positives = 101/192 (52%), Gaps = 25/192 (13%)

Query: 438  FTILQGPPGP--------RGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGP 489
            F  +QGPPGP         GP+G+ G QGPPG  G +G  G +G PG PG  G +G  G 
Sbjct: 1230 FPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGN 1289

Query: 490  AGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGL 549
             G PG  G  G KG QGP G +G+PG+PG  G  GDPG PG PG  G+ GP G PG  G 
Sbjct: 1290 PGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGP 1349

Query: 550  QGTVGEPGVPGPRGLP-------------GLPGVPGMPGPKGPPGPPGPSGAVVPLALQN 596
            +G  G  G PGP GLP             G PG+PG PG KG PGP GP G   P     
Sbjct: 1350 EGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTG--- 1406

Query: 597  EPTPAPEDNGCP 608
             P   P  NG P
Sbjct: 1407 -PPGDPGRNGLP 1417



 Score =  157 bits (396), Expect = 4e-38
 Identities = 85/173 (49%), Positives = 95/173 (54%), Gaps = 14/173 (8%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
           +G PG  G  G  G  GP GP G +GQKG+ G PGPPGP G RGP G  G PG  G  G 
Sbjct: 50  RGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGM 109

Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG---------LQGT 552
            G  G  G +G PG  G +G  G PG PG PG +G PGP G PG +G         L G 
Sbjct: 110 PGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGP 169

Query: 553 VGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDN 605
            G PG PGP G+ GLPG  G+PGP GPPGPPG  G   P  L     P P+ N
Sbjct: 170 KGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGL-----PGPKGN 217



 Score =  155 bits (393), Expect = 1e-37
 Identities = 85/184 (46%), Positives = 99/184 (53%), Gaps = 23/184 (12%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            G PG  GP+G+ G  G PG  G KG  G+ G PG PG  G +G  G  G PG  G  G K
Sbjct: 1074 GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPK 1133

Query: 503  GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV--PG 560
            G  GP G+ G PG+PGP G  G PG PGPPG++G PG  G PG  G +G  G+PG   PG
Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG 1193

Query: 561  PRGLPGL------------PGVPGMPGPKGPP---------GPPGPSGAVVPLALQNEPT 599
            P GLPGL            PG PG+PGPKG P         GPPGP G+  P     +  
Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGN 1253

Query: 600  PAPE 603
            P P+
Sbjct: 1254 PGPQ 1257



 Score =  154 bits (388), Expect = 4e-37
 Identities = 87/177 (49%), Positives = 95/177 (53%), Gaps = 15/177 (8%)

Query: 441  LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
            LQG PG  G  G +G  G PG  G  G KG  G PG  GP GE G IGP GPPG  G  G
Sbjct: 1310 LQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSG 1369

Query: 501  S----KGSQGPKGSRGSPGK---PGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553
                 KG  GP G  G PG    PGPQGP G PGP GPPG    PG  G PGF G  G  
Sbjct: 1370 QSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGD---PGRNGLPGFDGAGGRK 1426

Query: 554  GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAV--VPLALQNEPTPAPEDNGCP 608
            G+PG+PG  G  GL G PG  G +GPPGPPG S       +   ++ T AP+   CP
Sbjct: 1427 GDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQ---CP 1480



 Score =  153 bits (387), Expect = 5e-37
 Identities = 87/173 (50%), Positives = 94/173 (54%), Gaps = 14/173 (8%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501
           +GPPGPRG +GD G  GPPGP G +G  G  G PG PG  G  G  G  GP G  G  G+
Sbjct: 68  EGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGT 127

Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGK---EGLPGPQG------PPGFQGLQGT 552
           KG +G  GS G PG  GP GP G PG  G PG      LPGP+G      PPG QGL G 
Sbjct: 128 KGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGP 187

Query: 553 VGEP---GVPGPRGLPGLPGVPGMPGPKGPPGP--PGPSGAVVPLALQNEPTP 600
            G P   G PGP GL G PG PG+PGPKG  G    GP G      LQ  P P
Sbjct: 188 TGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 240



 Score =  152 bits (384), Expect = 1e-36
 Identities = 85/177 (48%), Positives = 94/177 (53%), Gaps = 26/177 (14%)

Query: 441  LQGPPGPRGP------------RGDRGSQGPPG---PTGNKGQKGEKGEPGPPGPA---- 481
            + GPPGP GP            +GD G QG PG   PTG KG KGE G PGPPGP     
Sbjct: 900  MMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNL 959

Query: 482  ----GERGPIGPAGPPGERGGKGSKGSQGPKGS---RGSPGKPGPQGPSGDPGPPGPPGK 534
                GE+G  G  G PG  G KG +G  G  G     G PG PGP GP G+PG PG PG 
Sbjct: 960  LGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGL 1019

Query: 535  EGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591
             G PG +G  G  G  G  G  G PGP G+PG PG PG+PG KG  G PG S   +P
Sbjct: 1020 IGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLP 1076



 Score =  151 bits (382), Expect = 2e-36
 Identities = 83/173 (47%), Positives = 96/173 (55%), Gaps = 11/173 (6%)

Query: 436  KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGE 495
            K +  L G PG  G  G  G  GPPGP GN G     G+PG  GP G +G IG  G PG 
Sbjct: 981  KGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGL---PGQPGLIGPPGLKGTIGDMGFPGP 1037

Query: 496  RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDP-----GPPGPPGKEGLPGPQGPPGFQGLQ 550
            +G +G  G  G  G  GSPG PG +G  GDP     G PG PG +G PG  G PG  G++
Sbjct: 1038 QGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIK 1097

Query: 551  GTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP---LALQNEPTP 600
            G+VG+PG+PG  G PG  G PG+PG  G PGPPGP G   P     L  EP P
Sbjct: 1098 GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGP 1150



 Score =  150 bits (380), Expect = 3e-36
 Identities = 86/183 (46%), Positives = 94/183 (51%), Gaps = 27/183 (14%)

Query: 443 GPPGPRGPRG--DRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG--PAGPPGERGG 498
           G PGP GP G    G QGPPGP G  G  G+ G  G PG  G+ GP G    GPPGERG 
Sbjct: 805 GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGS 864

Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDP---------GPPGPPGKEGLPGPQGPPGFQGL 549
            G  G+ GP G  GSPG PG  G SG P         GPPGPPG  G+PG  G PG +G 
Sbjct: 865 PGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924

Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGP--------------PGPPGPSGAVVPLALQ 595
            G  G+PG+PGP G  G  G PG+PGP GP              PG PG  G   P   Q
Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQ 984

Query: 596 NEP 598
             P
Sbjct: 985 GLP 987



 Score =  150 bits (379), Expect = 4e-36
 Identities = 89/197 (45%), Positives = 99/197 (50%), Gaps = 45/197 (22%)

Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKG-----EPGPPGPAGERGPIGPA 490
           K F  + GPPG  G  G  G +GPPGP G  G KGE G      PGPPG  G +G +GP 
Sbjct: 715 KGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPK 774

Query: 491 G------PPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPG--PPGPPGKEGLPGPQG 542
           G      PPG  G  G  G  GPKG  G  G+PGP GP G PG    GPPG  G+PGP G
Sbjct: 775 GDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIG 834

Query: 543 PPGFQGLQGTVGEPG-----VPGP---RGLPGLPGVPG---------MPGP--------- 576
            PG  G+ G  G+PG     VPGP   RG PG+PG PG         +PG          
Sbjct: 835 QPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGT 894

Query: 577 ------KGPPGPPGPSG 587
                  GPPGPPGP G
Sbjct: 895 KGEMGMMGPPGPPGPLG 911



 Score =  148 bits (373), Expect = 2e-35
 Identities = 92/209 (44%), Positives = 96/209 (45%), Gaps = 55/209 (26%)

Query: 438 FTILQGPPGPRGPRGDRGSQGP------PGPTGNKGQKGEKGEPGPPGPAGERGPIGPAG 491
           F  LQGPPGP G  G +G  G       PGP GN G  G  G  G PGP G  GPIGP G
Sbjct: 139 FPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPG 198

Query: 492 PPGERGGKGSKGS-----------QGPKGSRGSPGKPGPQGPSG---------------- 524
           PPG  G  G  G            QGPKG +G  G  GP GP G                
Sbjct: 199 PPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKG 258

Query: 525 ------DPGPPGPPGKEGLPGP----------QGPPGFQGLQGTVGEPGVPGPRGLPGLP 568
                 D GPPGPPG  G PGP          QG PG +G  G  GE G PG  GLPG P
Sbjct: 259 DQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDP 318

Query: 569 GVPGMPG------PKGPPGPPGPSGAVVP 591
           G PG PG       KG  GPPGP G V+P
Sbjct: 319 GYPGEPGRDGEKGQKGDTGPPGPPGLVIP 347



 Score =  147 bits (370), Expect = 5e-35
 Identities = 86/172 (50%), Positives = 94/172 (54%), Gaps = 12/172 (6%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQ---KGEKGEPGPPGPAGERGPIGPAGPP--GERG 497
           G PG  G  G  G  G PGP G  G    KGE+G PG PG  G  G IGP GPP  G  G
Sbjct: 570 GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG 629

Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSG----DPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553
             G KG QG  G+ G PG PGP+G  G     PG PG PG  G  G  G PG  GL G  
Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689

Query: 554 GEPGVPGPRGLPGLPGV--PGMPGPKGPPGPPGPSGAV-VPLALQNEPTPAP 602
           G PG+PG +G PG+PG+  PG PGPKG PG PGP GA   P  +  E  P P
Sbjct: 690 GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGP 741



 Score =  145 bits (366), Expect = 1e-34
 Identities = 90/221 (40%), Positives = 102/221 (46%), Gaps = 54/221 (24%)

Query: 441 LQGPPGPR---GPRGDRGSQGP-----PGPTGNKGQKGEKGEPGPPGPAGERGP------ 486
           + GPPGP    G RG +G +GP     PGP G  GQ G  G PGPPGPAG   P      
Sbjct: 392 VMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEIC 451

Query: 487 -IGPAGPPGERGGKGSKGSQGPKGSRG-------SPGKPGPQGPSGDPGPPGPPGKEGLP 538
             GP GPPG  G KG +G QG KG +G         G  GP G  G PG PGPPG  G P
Sbjct: 452 EPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFP 511

Query: 539 GPQ---------GPPGFQGLQGTVGEPGVPGPR----------------------GLPGL 567
           G +         GP G  G+ G  G PG PG +                      G PGL
Sbjct: 512 GQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGL 571

Query: 568 PGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608
           PG+PG PG  G PG PGP G    +  + E  P P + G P
Sbjct: 572 PGLPGTPGQDGLPGLPGPKGEPGGITFKGERGP-PGNPGLP 611



 Score =  145 bits (365), Expect = 2e-34
 Identities = 90/194 (46%), Positives = 96/194 (49%), Gaps = 27/194 (13%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
           L G PG +G  G  G  G PGP G KG  G  G PG PG  G  G  GP GPPG  G KG
Sbjct: 691 LPGIPGSKGEPGIPGI-GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG 749

Query: 501 SKGSQ--GPKGSRGSPGKPGPQGPSGD---PGPPGPPGKEGL---------------PGP 540
             G    GP G  G PG  G  GP GD   PGPPGPPG+ GL               PGP
Sbjct: 750 EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGP 809

Query: 541 QGPPGFQGL--QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPG--PPGPSGAVVPLALQN 596
            GPPG  G+  QG  G PG+PGP G PGL G+PG  G  GPPG   PGP G      +  
Sbjct: 810 MGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPG 869

Query: 597 EPTP--APEDNGCP 608
            P P   P   G P
Sbjct: 870 APGPIGPPGSPGLP 883



 Score =  144 bits (364), Expect = 2e-34
 Identities = 84/182 (46%), Positives = 98/182 (53%), Gaps = 42/182 (23%)

Query: 446 GPRGPRGDRGSQGPPGPTGN----------KGQKGEKGEPGPPGPAGERGPIGPAGPPGE 495
           GP+G +G++G QGPPGP G           + QKG++G PG  GP G  G  GP GPPG 
Sbjct: 224 GPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG- 282

Query: 496 RGGKGSKGSQGPKGSRGSPGK------PGPQGPSGDPGPPGPPGKEGL------PGPQGP 543
            G KG KG QG  G RG PGK      PG  G  GDPG PG PG++G        GP GP
Sbjct: 283 -GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGP 341

Query: 544 PGFQ----------GLQGTVGEPGVP---GPRGLPGLPGVPGMPGP-----KGPPGPPGP 585
           PG            G +G +G PG+P   G RG PG+ G PG+PGP      GPPGPPG 
Sbjct: 342 PGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGF 401

Query: 586 SG 587
            G
Sbjct: 402 PG 403



 Score =  143 bits (361), Expect = 5e-34
 Identities = 92/213 (43%), Positives = 104/213 (48%), Gaps = 59/213 (27%)

Query: 442 QGPPGPRGPRGDRGSQGPPGPTGN-KGQKGEKGEPGP---------------------PG 479
           QG PG RGP G  G +GPPGP G  KG+KGE+GEPG                      PG
Sbjct: 260 QGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPG 319

Query: 480 PAGE---------RGPIGPAGPPG---ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPG 527
             GE         +G  GP GPPG    R G G   + G KG+ G PG PG +G  G PG
Sbjct: 320 YPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGI--TIGEKGNIGLPGLPGEKGERGFPG 377

Query: 528 PPGPPGKEGLP-----GPQGPPGFQGLQGTVGEPG-----VPGPRGLPGLPGVPGMPGPK 577
             GPPG  G P     GP GPPGF G +G  G+ G     +PGP GL G PG PG+PGP 
Sbjct: 378 IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPP 437

Query: 578 GP-------------PGPPGPSGAVVPLALQNE 597
           GP             PGPPGP G+     LQ E
Sbjct: 438 GPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGE 470



 Score =  143 bits (360), Expect = 7e-34
 Identities = 80/156 (51%), Positives = 84/156 (53%), Gaps = 11/156 (7%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPA----GPPGER 496
           L G PG  GP G  G  GPPGP G KG +G  G PG PG  G +G  G      G PG  
Sbjct: 610 LPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLP 668

Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556
           G  G  G  G  G  G PG+PG  G  G  G PG PG  GLPGP GP GF G+ G  G P
Sbjct: 669 GNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI-GLPGPPGPKGFPGIPGPPGAP 727

Query: 557 GVPGPRGLPGLPGVPGMPGPKGP-----PGPPGPSG 587
           G PG  GL G PG PG PGPKG      PGPPGP G
Sbjct: 728 GTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPG 763



 Score =  142 bits (359), Expect = 9e-34
 Identities = 82/196 (41%), Positives = 94/196 (47%), Gaps = 29/196 (14%)

Query: 443  GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
            G PGP GP+G+ G  G PG  G  G KG  G+ G PGP G  GP GP+G PG+ G  G  
Sbjct: 1000 GLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLP 1059

Query: 503  GSQGPKG-----SRGSPGKPGPQGPSGDPGPPGPPGKEG--------------------- 536
            G +G KG     S G PG PGP+G  G PG PG PG +G                     
Sbjct: 1060 GQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPG 1119

Query: 537  ---LPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLA 593
                PG  GPPG +G+ G  G PG+PG  G  G  G PG PGP G  G PG  G   P  
Sbjct: 1120 LPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG 1179

Query: 594  LQNEPTPAPEDNGCPP 609
             + EP      N  PP
Sbjct: 1180 QKGEPGQPGFGNPGPP 1195



 Score =  141 bits (356), Expect = 2e-33
 Identities = 82/188 (43%), Positives = 94/188 (50%), Gaps = 20/188 (10%)

Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500
           + GPPGP+G RG  G  G PG  G  G  G  G PGP G  G  G  G  G PG  G  G
Sbjct: 82  IPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG 141

Query: 501 SKGSQGPKGSRGSPGKPGP------QGPSGDPGPPGPPGKEGLPGPQ------GPPGFQG 548
            +G  GP G  G  G+PG        GP G+PG PGPPG +GLPGP       GPPG  G
Sbjct: 142 LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPG 201

Query: 549 LQGTVGEPGVPGPRGLPGL--PGVPGMPGPKGPPGPPGPSGAV------VPLALQNEPTP 600
           L G  G PG+PGP+G  GL   G  G  G +G  GPPGP G +      + +  Q     
Sbjct: 202 LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261

Query: 601 APEDNGCP 608
            P D G P
Sbjct: 262 LPGDRGPP 269



 Score =  140 bits (353), Expect = 4e-33
 Identities = 82/179 (45%), Positives = 91/179 (50%), Gaps = 34/179 (18%)

Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQK-------GEKGEPGPPGPAGERGPIGPAGPPGE 495
           GPPGP G  GD+G QG  G  G+KG         G  G PG PG  G  GP G  G PG+
Sbjct: 454 GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQ 513

Query: 496 RGGKGSKGSQGPKGSRGSPGKPGP-------------------QGPSGDPGPPGPPGKEG 536
           +G KG  G+ GPKG  G PG PG                    +G  G+ G PG PG  G
Sbjct: 514 KGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573

Query: 537 LPGPQGPPGFQGLQGTVGEPG---VPGPRGLPGLPGVPGMP---GPKGPP--GPPGPSG 587
           LPG  G  G  GL G  GEPG     G RG PG PG+PG+P   GP GPP  GPPGP G
Sbjct: 574 LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVG 632



 Score =  139 bits (350), Expect = 9e-33
 Identities = 81/183 (44%), Positives = 97/183 (53%), Gaps = 25/183 (13%)

Query: 443 GPPGPRGPRGDRGSQ----GPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP------ 492
           G PG  GP+GD G      G PG  GN G+ G+ G PG PG  G+ G  G  G       
Sbjct: 644 GQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGI 703

Query: 493 -----PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG--LPGPQGP-- 543
                PG  G KG  G  GP G+ G+PG+ G +GP G PG PGP G+ G  LPGP GP  
Sbjct: 704 PGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPG 763

Query: 544 -PGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP-----LALQNE 597
            PGF+G  G  G+ G PGP G PG  G+ G+PGPKG  GP G  G + P     + +Q  
Sbjct: 764 LPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGP 823

Query: 598 PTP 600
           P P
Sbjct: 824 PGP 826



 Score =  135 bits (341), Expect = 1e-31
 Identities = 72/140 (51%), Positives = 80/140 (57%), Gaps = 15/140 (10%)

Query: 463 TGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGP 522
           +G KG+KGE+G PG  G  G  G  GP GPPG RG KG  G  GP G +G  G PG  G 
Sbjct: 41  SGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGF 100

Query: 523 SGDPGPPGPPGKEGLPGPQGPPGFQGLQGT---VGEPGVPGPRGLPGLPGVPGM------ 573
            G PG PG PG +G PGPQG PG  G +G     G PG PG +G PG PG+PGM      
Sbjct: 101 PGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGS 160

Query: 574 ------PGPKGPPGPPGPSG 587
                 PGPKG PG PGP G
Sbjct: 161 IIMSSLPGPKGNPGYPGPPG 180



 Score =  134 bits (336), Expect = 4e-31
 Identities = 87/206 (42%), Positives = 101/206 (49%), Gaps = 41/206 (19%)

Query: 443 GPPGPRG---PR-------GDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP--IGPA 490
           GPPGP G   PR       G++G+ G PG  G KG++G  G  GPPG  G  G   +GP 
Sbjct: 337 GPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPP 396

Query: 491 GPPGERGGKGSKGSQGPKG-----------SRGSPGKPGPQGPSG----------DPGPP 529
           GPPG  G +G KG +GP G             G+PG PGP GP+G          +PGPP
Sbjct: 397 GPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPP 456

Query: 530 GPPGKEGLPGPQGPPGFQGLQGTV-------GEPGVPGPRGLPGLPGVPGMPGPKGPPGP 582
           GPPG  G  G QG  G +G +G         G  G PG  GLPGLPG PG  G  G  G 
Sbjct: 457 GPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGE 516

Query: 583 PGPSGAVVPLALQNEPTPAPEDNGCP 608
            G +GA  P  L   P  AP   G P
Sbjct: 517 KGQAGATGPKGLPGIP-GAPGAPGFP 541



 Score =  124 bits (311), Expect = 3e-28
 Identities = 86/230 (37%), Positives = 98/230 (42%), Gaps = 81/230 (35%)

Query: 439 TILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP------PGPAGERGPIGPAGP 492
           T + GPPG  G  G  G  G  G  G KG+KG+ G  GP      PG  G  G  G  G 
Sbjct: 487 TGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGE 546

Query: 493 PGE-------RGGKGSKGSQGPKGSRGSPGKPGPQ------GPSGDP---------GPPG 530
           PG+       +G KG  GS G  G  G PG PG        GP G+P         GPPG
Sbjct: 547 PGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPG 606

Query: 531 PPGKEGLP---GPQGPPGF-----------QGLQGTVGEPGVPGPR-------------- 562
            PG  GLP   GP GPPGF           QG+ G  G+PG+PGP+              
Sbjct: 607 NPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPG 666

Query: 563 -----------------GLPGLPGVPGMPGPKGP--------PGPPGPSG 587
                            GLPG PG+PG+PG KG         PGPPGP G
Sbjct: 667 LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKG 716



 Score =  111 bits (277), Expect = 3e-24
 Identities = 64/152 (42%), Positives = 75/152 (49%), Gaps = 13/152 (8%)

Query: 467 GQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDP 526
           GQ  E        P  +    G  G  GERG  G +G  G  G  G  G PGP+G  GD 
Sbjct: 21  GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80

Query: 527 GPPGPPGKEGLPGPQGPPGFQGLQGTVGEP---GVPGPRGLP---------GLPGVPGMP 574
           G PGPPG +G+ GP G PGF G  G  G P   G PGP+G+P         G PG PG P
Sbjct: 81  GIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP 140

Query: 575 GPKGPPGPPG-PSGAVVPLALQNEPTPAPEDN 605
           G +GPPGPPG P     P ++     P P+ N
Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGN 172



 Score = 80.1 bits (196), Expect = 7e-15
 Identities = 45/106 (42%), Positives = 52/106 (49%), Gaps = 21/106 (19%)

Query: 440  ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499
            I++G  GP G  G  G +G PGP                GP G  GP GP G PG  G  
Sbjct: 1373 IIKGDAGPPGIPGQPGLKGLPGP---------------QGPQGLPGPTGPPGDPGRNGLP 1417

Query: 500  GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPG 545
            G  G+ G KG  G PG+PG +G        GPPG +GL GP GPPG
Sbjct: 1418 GFDGAGGRKGDPGLPGQPGTRGLD------GPPGPDGLQGPPGPPG 1457


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.133    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,810,230
Number of Sequences: 37866
Number of extensions: 2721550
Number of successful extensions: 83165
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 689
Number of HSP's successfully gapped in prelim test: 1857
Number of HSP's that attempted gapping in prelim test: 15043
Number of HSP's gapped (non-prelim): 17970
length of query: 742
length of database: 18,247,518
effective HSP length: 110
effective length of query: 632
effective length of database: 14,082,258
effective search space: 8899987056
effective search space used: 8899987056
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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