BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|18641360 collectin sub-family member 12 [Homo sapiens] (742 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|18641360 collectin sub-family member 12 [Homo sapiens] 1526 0.0 gi|33598924 scavenger receptor class A, member 3 isoform 1 [Homo... 351 1e-96 gi|33598922 scavenger receptor class A, member 3 isoform 2 [Homo... 196 5e-50 gi|61699226 pulmonary surfactant-associated protein D precursor ... 180 4e-45 gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] 175 2e-43 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 172 1e-42 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 171 3e-42 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 169 9e-42 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 169 9e-42 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 169 9e-42 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 168 1e-41 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 168 2e-41 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 168 2e-41 gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 166 6e-41 gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 166 6e-41 gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 166 6e-41 gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 166 6e-41 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 166 7e-41 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 166 9e-41 gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 165 2e-40 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 162 1e-39 gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] 162 1e-39 gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens] 162 1e-39 gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 162 1e-39 gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 162 1e-39 gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 162 1e-39 gi|48762934 alpha 2 type I collagen [Homo sapiens] 161 2e-39 gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 161 2e-39 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 160 3e-39 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 160 4e-39 >gi|18641360 collectin sub-family member 12 [Homo sapiens] Length = 742 Score = 1526 bits (3950), Expect = 0.0 Identities = 742/742 (100%), Positives = 742/742 (100%) Query: 1 MKDDFAEEEEVQSFGYKRFGIQEGTQCTKCKNNWALKFSIILLYILCALLTITVAILGYK 60 MKDDFAEEEEVQSFGYKRFGIQEGTQCTKCKNNWALKFSIILLYILCALLTITVAILGYK Sbjct: 1 MKDDFAEEEEVQSFGYKRFGIQEGTQCTKCKNNWALKFSIILLYILCALLTITVAILGYK 60 Query: 61 VVEKMDNVTGGMETSRQTYDDKLTAVESDLKKLGDQTGKKAISTNSELSTFRSDILDLRQ 120 VVEKMDNVTGGMETSRQTYDDKLTAVESDLKKLGDQTGKKAISTNSELSTFRSDILDLRQ Sbjct: 61 VVEKMDNVTGGMETSRQTYDDKLTAVESDLKKLGDQTGKKAISTNSELSTFRSDILDLRQ 120 Query: 121 QLREITEKTSKNKDTLEKLQASGDALVDRQSQLKETLENNSFLITTVNKTLQAYNGYVTN 180 QLREITEKTSKNKDTLEKLQASGDALVDRQSQLKETLENNSFLITTVNKTLQAYNGYVTN Sbjct: 121 QLREITEKTSKNKDTLEKLQASGDALVDRQSQLKETLENNSFLITTVNKTLQAYNGYVTN 180 Query: 181 LQQDTSVLQGNLQNQMYSHNVVIMNLNNLNLTQVQQRNLITNLQRSVDDTSQAIQRIKND 240 LQQDTSVLQGNLQNQMYSHNVVIMNLNNLNLTQVQQRNLITNLQRSVDDTSQAIQRIKND Sbjct: 181 LQQDTSVLQGNLQNQMYSHNVVIMNLNNLNLTQVQQRNLITNLQRSVDDTSQAIQRIKND 240 Query: 241 FQNLQQVFLQAKKDTDWLKEKVQSLQTLAANNSALAKANNDTLEDMNSQLNSFTGQMENI 300 FQNLQQVFLQAKKDTDWLKEKVQSLQTLAANNSALAKANNDTLEDMNSQLNSFTGQMENI Sbjct: 241 FQNLQQVFLQAKKDTDWLKEKVQSLQTLAANNSALAKANNDTLEDMNSQLNSFTGQMENI 300 Query: 301 TTISQANEQNLKDLQDLHKDAENRTAIKFNQLEERFQLFETDIVNIISNISYTAHHLRTL 360 TTISQANEQNLKDLQDLHKDAENRTAIKFNQLEERFQLFETDIVNIISNISYTAHHLRTL Sbjct: 301 TTISQANEQNLKDLQDLHKDAENRTAIKFNQLEERFQLFETDIVNIISNISYTAHHLRTL 360 Query: 361 TSNLNEVRTTCTDTLTKHTDDLTSLNNTLANIRLDSVSLRMQQDLMRSRLDTEVANLSVI 420 TSNLNEVRTTCTDTLTKHTDDLTSLNNTLANIRLDSVSLRMQQDLMRSRLDTEVANLSVI Sbjct: 361 TSNLNEVRTTCTDTLTKHTDDLTSLNNTLANIRLDSVSLRMQQDLMRSRLDTEVANLSVI 420 Query: 421 MEEMKLVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGP 480 MEEMKLVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGP Sbjct: 421 MEEMKLVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGP 480 Query: 481 AGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP 540 AGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP Sbjct: 481 AGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP 540 Query: 541 QGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP 600 QGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP Sbjct: 541 QGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP 600 Query: 601 APEDNGCPPHWKNFTDKCYYFSVEKEIFEDAKLFCEDKSSHLVFINTREEQQWIKKQMVG 660 APEDNGCPPHWKNFTDKCYYFSVEKEIFEDAKLFCEDKSSHLVFINTREEQQWIKKQMVG Sbjct: 601 APEDNGCPPHWKNFTDKCYYFSVEKEIFEDAKLFCEDKSSHLVFINTREEQQWIKKQMVG 660 Query: 661 RESHWIGLTDSERENEWKWLDGTSPDYKNWKAGQPDNWGHGHGPGEDCAGLIYAGQWNDF 720 RESHWIGLTDSERENEWKWLDGTSPDYKNWKAGQPDNWGHGHGPGEDCAGLIYAGQWNDF Sbjct: 661 RESHWIGLTDSERENEWKWLDGTSPDYKNWKAGQPDNWGHGHGPGEDCAGLIYAGQWNDF 720 Query: 721 QCEDVNNFICEKDRETVLSSAL 742 QCEDVNNFICEKDRETVLSSAL Sbjct: 721 QCEDVNNFICEKDRETVLSSAL 742 >gi|33598924 scavenger receptor class A, member 3 isoform 1 [Homo sapiens] Length = 606 Score = 351 bits (901), Expect = 1e-96 Identities = 203/587 (34%), Positives = 324/587 (55%), Gaps = 2/587 (0%) Query: 2 KDDFAEEEEVQSFGYKRFGIQEGTQCTKCKNNWALKFSIILLYILCALLTITVAILGYKV 61 +D ++E++ +F + G + G +C++C+ N +L S+ +LY+ ALL + VA+L V Sbjct: 18 EDLAGDDEDMPTFPCTQKG-RPGPRCSRCQKNLSLHTSVRILYLFLALLLVAVAVLASLV 76 Query: 62 VEKMDNVTGGMETSRQTYDDKLTAVESDLKKLGDQTGKKAISTNSELSTFRSDILDLRQQ 121 K+D+++ + ++ YD KL ++ +L+ L D S E +I L+++ Sbjct: 77 FRKVDSLSEDISLTQSIYDKKLVLMQKNLQGL-DPKALNNCSFCHEAGQLGPEIRKLQEE 135 Query: 122 LREITEKTSKNKDTLEKLQASGDALVDRQSQLKETLENNSFLITTVNKTLQAYNGYVTNL 181 L I + + L++ + + L Q+ + + + SF I VN++L + V Sbjct: 136 LEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQVNQSLGLFLAQVRGW 195 Query: 182 QQDTSVLQGNLQNQMYSHNVVIMNLNNLNLTQVQQRNLITNLQRSVDDTSQAIQRIKNDF 241 Q T+ L +L++ V ++ +N T Q I +QR D+ + +Q+I D+ Sbjct: 196 QATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRKTDEETLTLQKIVTDW 255 Query: 242 QNLQQVFLQAKKDTDWLKEKVQSLQTLAANNSALAKANNDTLEDMNSQLNSFTGQMENIT 301 QN ++F + + E V+++Q +S N++++ D+ Q+ Q++NI+ Sbjct: 256 QNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDLVLQVMGLQLQLDNIS 315 Query: 302 TISQANEQNLKDLQDLHKDAENRTAIKFNQLEERFQLFETDIVNIISNISYTAHHLRTLT 361 + +E+N+ DLQ A+NRT +F LE R E +I I +NI+ T +H+ ++ Sbjct: 316 SFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTIFTNINATDNHVHSML 375 Query: 362 SNLNEVRTTCTDTLTKHTDDLTSLNNTLANIRLDSVSLRMQQDLMRSRLDTEVANLSVIM 421 L++VR +CT H ++L LN +++ + + LR + L+ +RLD V NLS+I+ Sbjct: 376 KYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLLSARLDLNVRNLSMIV 435 Query: 422 EEMKLVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPA 481 EEMK VD++HG++++N TIL+G PGP GPRG +G G GP G +G KG+ G GP GP Sbjct: 436 EEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQ 495 Query: 482 GERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQ 541 G +G G AGP GERG G +G G KGS+GS G GP+G G G GPPG EG PG Sbjct: 496 GPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP 555 Query: 542 GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588 GP G QG G G+ G PG RG G G PG+ GP G PGPPGP G+ Sbjct: 556 GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 Score = 43.1 bits (100), Expect = 0.001 Identities = 25/53 (47%), Positives = 25/53 (47%), Gaps = 3/53 (5%) Query: 554 GEPGVPGPRGLPGLPGVPGMPG---PKGPPGPPGPSGAVVPLALQNEPTPAPE 603 G PG PGPRG G GV G G PKG PG GP G P E P E Sbjct: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509 >gi|33598922 scavenger receptor class A, member 3 isoform 2 [Homo sapiens] Length = 466 Score = 196 bits (499), Expect = 5e-50 Identities = 125/442 (28%), Positives = 236/442 (53%), Gaps = 2/442 (0%) Query: 2 KDDFAEEEEVQSFGYKRFGIQEGTQCTKCKNNWALKFSIILLYILCALLTITVAILGYKV 61 +D ++E++ +F + G + G +C++C+ N +L S+ +LY+ ALL + VA+L V Sbjct: 18 EDLAGDDEDMPTFPCTQKG-RPGPRCSRCQKNLSLHTSVRILYLFLALLLVAVAVLASLV 76 Query: 62 VEKMDNVTGGMETSRQTYDDKLTAVESDLKKLGDQTGKKAISTNSELSTFRSDILDLRQQ 121 K+D+++ + ++ YD KL ++ +L+ L D S E +I L+++ Sbjct: 77 FRKVDSLSEDISLTQSIYDKKLVLMQKNLQGL-DPKALNNCSFCHEAGQLGPEIRKLQEE 135 Query: 122 LREITEKTSKNKDTLEKLQASGDALVDRQSQLKETLENNSFLITTVNKTLQAYNGYVTNL 181 L I + + L++ + + L Q+ + + + SF I VN++L + V Sbjct: 136 LEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQVNQSLGLFLAQVRGW 195 Query: 182 QQDTSVLQGNLQNQMYSHNVVIMNLNNLNLTQVQQRNLITNLQRSVDDTSQAIQRIKNDF 241 Q T+ L +L++ V ++ +N T Q I +QR D+ + +Q+I D+ Sbjct: 196 QATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRKTDEETLTLQKIVTDW 255 Query: 242 QNLQQVFLQAKKDTDWLKEKVQSLQTLAANNSALAKANNDTLEDMNSQLNSFTGQMENIT 301 QN ++F + + E V+++Q +S N++++ D+ Q+ Q++NI+ Sbjct: 256 QNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDLVLQVMGLQLQLDNIS 315 Query: 302 TISQANEQNLKDLQDLHKDAENRTAIKFNQLEERFQLFETDIVNIISNISYTAHHLRTLT 361 + +E+N+ DLQ A+NRT +F LE R E +I I +NI+ T +H+ ++ Sbjct: 316 SFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTIFTNINATDNHVHSML 375 Query: 362 SNLNEVRTTCTDTLTKHTDDLTSLNNTLANIRLDSVSLRMQQDLMRSRLDTEVANLSVIM 421 L++VR +CT H ++L LN +++ + + LR + L+ +RLD V NLS+I+ Sbjct: 376 KYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLLSARLDLNVRNLSMIV 435 Query: 422 EEMKLVDSKHGQLIKNFTILQG 443 EEMK VD++HG++++N TIL+G Sbjct: 436 EEMKAVDTQHGEILRNVTILRG 457 >gi|61699226 pulmonary surfactant-associated protein D precursor [Homo sapiens] Length = 375 Score = 180 bits (457), Expect = 4e-45 Identities = 106/302 (35%), Positives = 149/302 (49%), Gaps = 15/302 (4%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 + G GP GP+GD GS G PGP G+ G G G PG PGPAG GP+G G G +G G Sbjct: 77 MPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGREGPLGKQGNIGPQGKPG 136 Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP---PGKEGLPGPQGPPGFQGLQGTVGEPG 557 KG GPKG G+PG G G G GP G PG+ G+PG G G G G G PG Sbjct: 137 PKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTGAAGSAGAMGPQGSPG 196 Query: 558 VPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPL-ALQNEPTPAP------EDNGCPPH 610 GP GL G G+PG G KG G P + + ALQ + + P+ Sbjct: 197 ARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHLQAAFSQYKKVELFPN 256 Query: 611 WKNFTDKCYYFSVEKEIFEDAKLFCEDKSSHLVFINTREEQQWIKKQMVGR-ESHWIGLT 669 ++ +K + + + F +A+L C L + E +++ +V + E+ ++ +T Sbjct: 257 GQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAALQQLVVAKNEAAFLSMT 316 Query: 670 DSERENEWKWLDGTSPDYKNWKAGQPDNWGHGHGPGEDCAGLIYAGQWNDFQCEDVNNFI 729 DS+ E ++ + G S Y NW G+P++ G EDC + G+WND C + + Sbjct: 317 DSKTEGKFTYPTGESLVYSNWAPGEPND----DGGSEDCVEIFTNGKWNDRACGEKRLVV 372 Query: 730 CE 731 CE Sbjct: 373 CE 374 Score = 93.2 bits (230), Expect = 8e-19 Identities = 48/103 (46%), Positives = 57/103 (55%), Gaps = 3/103 (2%) Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPG 560 S G G G G+ GP+G GDPG PG G+ G+PG GP G +G G+VGEPG G Sbjct: 41 SSVESGLPGRDGRDGREGPRGEKGDPGLPGAAGQAGMPGQAGPVGPKGDNGSVGEPGPKG 100 Query: 561 PRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPE 603 G G PG PG+PGP G GP G G + P Q +P P E Sbjct: 101 DTGPSGPPGPPGVPGPAGREGPLGKQGNIGP---QGKPGPKGE 140 >gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] Length = 1604 Score = 175 bits (443), Expect = 2e-43 Identities = 90/179 (50%), Positives = 103/179 (57%), Gaps = 18/179 (10%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 L GPPGP GPRG+RG QG G G++G +G+ G PGPPGP G G +G GPPG + KG Sbjct: 1127 LPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKG 1186 Query: 501 SKGSQGPKGSRGSPGKPGP---QGPS---------------GDPGPPGPPGKEGLPGPQG 542 S+G +GP G GSPG PGP QGP+ GDPGP GPPG G PG +G Sbjct: 1187 SEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKG 1246 Query: 543 PPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601 G GL G G+ G PGP G G PG G PG GP G PGP G V P +P PA Sbjct: 1247 KTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPA 1305 Score = 167 bits (423), Expect = 3e-41 Identities = 83/162 (51%), Positives = 98/162 (60%), Gaps = 12/162 (7%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKG------EKGEPGPPGPAGERGPIGPAGPPGE 495 +G PGP G G G+ GPPG G KG++G EKGEPGPPG G GP GPAGP GE Sbjct: 1080 KGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGE 1139 Query: 496 RGGKGSKGSQGPKGSRGSPGKPGPQGPSG------DPGPPGPPGKEGLPGPQGPPGFQGL 549 RG +G+ G +G +G +G PG PGP GP G PGPPGP ++G G +GP G G Sbjct: 1140 RGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGS 1199 Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 G G PG+ GP GL GL G G PG +G PGP GP G + P Sbjct: 1200 PGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGP 1241 Score = 157 bits (396), Expect = 4e-38 Identities = 91/204 (44%), Positives = 107/204 (52%), Gaps = 31/204 (15%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKG------EKGEPGPPGPAGERGPIGPAGPPGER 496 GPPGP GP G G+ G PG G +G++G +KGEPGPPG G G GP G PG + Sbjct: 1045 GPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIK 1104 Query: 497 GGKG------SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG---------LPGPQ 541 G +G KG GP GS G PG PGP GP G+ GP G G++G PGP Sbjct: 1105 GERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPP 1164 Query: 542 GPPGFQGLQGTVGEP---------GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPL 592 GPPGF G G+ G P G+ GP GLPG PG PG PG +GP G G G Sbjct: 1165 GPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKP 1224 Query: 593 ALQNEPTPA-PEDNGCPPHWKNFT 615 L+ +P PA P PP +K T Sbjct: 1225 GLRGDPGPAGPPGLMGPPGFKGKT 1248 Score = 155 bits (393), Expect = 1e-37 Identities = 78/159 (49%), Positives = 88/159 (55%), Gaps = 14/159 (8%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERG----- 497 G PG GP+GD G GPPG TG G +GE G GP G G G +GP GPPG+ G Sbjct: 1249 GHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGIS 1308 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557 G KG +G G RG G PG GP G PGPPG PG +G G +GPPG QG G G G Sbjct: 1309 AVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKG 1368 Query: 558 VP---------GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 P G +G G+PG PG G GP GPPGP+G Sbjct: 1369 DPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAG 1407 Score = 147 bits (371), Expect = 3e-35 Identities = 82/175 (46%), Positives = 88/175 (50%), Gaps = 15/175 (8%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---PAGPPGERG 497 L G G GP G RGS GPPGP G G G G PG PG GERG G G PG G Sbjct: 1028 LPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPG 1087 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGP------------PG 545 G G+ GP G G G+ G G +G+ G PGPPG EGLPGP GP G Sbjct: 1088 QPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSG 1147 Query: 546 FQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP 600 +G QG G+PG PGP G PG PG G PGP GP G G P L P P Sbjct: 1148 EKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGP 1202 Score = 141 bits (356), Expect = 2e-33 Identities = 84/215 (39%), Positives = 98/215 (45%), Gaps = 55/215 (25%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +GPPG +G G G +G PG G KGQ GEKG G PG G+ G +GP GPPG G +G Sbjct: 1352 EGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGH 1411 Query: 502 KGSQGPKGSRG------------------------------------------------S 513 G+ GP GS G + Sbjct: 1412 PGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA 1471 Query: 514 PGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR-----GLPGLP 568 PG+PGP G G PG PG PG GLPG G G QGL G G PG G + G+ G Sbjct: 1472 PGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGEN 1531 Query: 569 GVPGMPGPKGPPGPPGPSGAVVPLALQNEP-TPAP 602 G+PG PGP+GPPG G GA P+ Q P P P Sbjct: 1532 GLPGPPGPQGPPG-YGKMGATGPMGQQGIPGIPGP 1565 Score = 140 bits (354), Expect = 3e-33 Identities = 83/187 (44%), Positives = 98/187 (52%), Gaps = 36/187 (19%) Query: 431 HGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEP--------------G 476 HG N T+ P GP+G +G +G PGP G+KG+KG +G G Sbjct: 321 HGARDSNVTL-----APSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEG 375 Query: 477 PPGPAGERGPIGPAGPPG---ERGGKGSKGSQGPKGSRGSPGKP---------GPQGPSG 524 P G GE G +GP+G PG E+G KG KG G KG G PG+ GP+G G Sbjct: 376 PKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKG 435 Query: 525 DPGPPGPPGKEGLPGP---QGPPGFQGLQGTVGEP-GVPGPRGLPGLPGVPGMPGPKGPP 580 DPG GP G G PGP GPPG GL GT G+P G PGP+G G G+PG GP G P Sbjct: 436 DPGFVGPEGLAGEPGPPGLPGPPGI-GLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKP 494 Query: 581 GPPGPSG 587 G PG G Sbjct: 495 GKPGVKG 501 Score = 140 bits (352), Expect = 6e-33 Identities = 72/147 (48%), Positives = 80/147 (54%) Query: 452 GDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSR 511 GD G G PG G G G++GE GPPG G GP GP GPPG G GS G G +G R Sbjct: 1012 GDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGER 1071 Query: 512 GSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVP 571 G G G +G G PG PG PG G PG G G +G G+ GE G PGP G GLPG P Sbjct: 1072 GLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPP 1131 Query: 572 GMPGPKGPPGPPGPSGAVVPLALQNEP 598 G GP+G GP G SG Q +P Sbjct: 1132 GPAGPRGERGPQGNSGEKGDQGFQGQP 1158 Score = 138 bits (347), Expect = 2e-32 Identities = 80/181 (44%), Positives = 92/181 (50%), Gaps = 26/181 (14%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGE---------------KGEPGPPGPAGERGPI 487 G PG G G G G GP G KG+KG+ G PG PGP GE+GP Sbjct: 694 GTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPE 753 Query: 488 GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGP-----QGPSGDPGPPGPPGKEGLPGPQG 542 G G PG+ G G G QGP G +G G+PGP QGP G+PG PG PG +GLPGP+G Sbjct: 754 G-VGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRG 812 Query: 543 PPGFQGLQGTVGEPGVPGPRGLPGLPGV-----PGMPGPKGPPGPPGPSGAVVPLALQNE 597 PPG G +G G PGV G G G PG PG G +G G G G P + E Sbjct: 813 PPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGE 872 Query: 598 P 598 P Sbjct: 873 P 873 Score = 138 bits (347), Expect = 2e-32 Identities = 77/173 (44%), Positives = 84/173 (48%), Gaps = 18/173 (10%) Query: 449 GPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPK 508 G G GS G PGP G GQ+GE+G PG G G GPIGP G PG G G G QG + Sbjct: 1012 GDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGER 1071 Query: 509 GSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLP 568 G G G G GP G PG PG G GLPG +G G+ G G GEPG PG GLPG P Sbjct: 1072 GLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPP 1131 Query: 569 GVPGMPGPKGP------------------PGPPGPSGAVVPLALQNEPTPAPE 603 G G G +GP PGPPGP G + P P E Sbjct: 1132 GPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAE 1184 Score = 135 bits (339), Expect = 2e-31 Identities = 80/187 (42%), Positives = 98/187 (52%), Gaps = 26/187 (13%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PG +GP G +G QG PGP G +G +G +GEPG PG G +G GP GPPG G KG++ Sbjct: 765 GLPGVQGPPGLKGVQGEPGPPG-RGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQ 823 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG----- 557 GS G KG+ G G PG + GPPG G++G G +G PG +G +G GEPG Sbjct: 824 GSPGVKGATGPVGPPG----ASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCP 879 Query: 558 ---------VPGPRGL-------PGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601 +PG GL PG G PG+PGP GPPG PG G L +P Sbjct: 880 SQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLT 939 Query: 602 PEDNGCP 608 E P Sbjct: 940 AELGSLP 946 Score = 133 bits (335), Expect = 5e-31 Identities = 82/189 (43%), Positives = 95/189 (50%), Gaps = 30/189 (15%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEP------------------GPPGPAG 482 L+G G G G GS GPPGP G G KG KGEP PGP+G Sbjct: 597 LKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSG 656 Query: 483 ERGPIGPAG--PPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP 540 E+G GP G PG++G G +G +G KG G+PG PG G +G PG G PG +G GP Sbjct: 657 EKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGP 716 Query: 541 QGPPG-----FQGLQGTV----GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 +G G LQGTV G PG PGP+G G GV G PG G PG PG G Sbjct: 717 KGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGV-GRPGKPGQPGLPGVQGPPGL 775 Query: 592 LALQNEPTP 600 +Q EP P Sbjct: 776 KGVQGEPGP 784 Score = 132 bits (332), Expect = 1e-30 Identities = 81/203 (39%), Positives = 101/203 (49%), Gaps = 37/203 (18%) Query: 439 TILQGPPGPRGPRGDRGSQGP-----------PGPTGNKGQKGEKGEPGPPGPA--GERG 485 T + G PG GP+G++G +G PG G G KG +GEPGPPG G +G Sbjct: 735 TDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQG 794 Query: 486 PIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPP-----GPPGKEGLPGP 540 G G PG +G G +G GP G +G+ G PG +G +G GPP GPPG++G G Sbjct: 795 EPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQ 854 Query: 541 QGPPGFQGLQGTVGEPGVPGPRGLP--------GLPGVPGM-------PGPKGPPGPPGP 585 G G G +G GE G PG P G+PG PG+ PGP+GPPG PGP Sbjct: 855 TGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGP 914 Query: 586 SGAVVPLALQNEPTPAPEDNGCP 608 G LQ P +NG P Sbjct: 915 PGPPGVPGLQG----VPGNNGLP 933 Score = 130 bits (328), Expect = 3e-30 Identities = 69/144 (47%), Positives = 77/144 (53%), Gaps = 2/144 (1%) Query: 443 GPPGPRGPRGDRGSQGPPG--PTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 GPPG GP G G GP G G KG +G GE G G G+ GP G GPPGE G G Sbjct: 1288 GPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDG 1347 Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPG 560 + G +GP G +G G PGP+G G G G G++G G G PG G G VG PG G Sbjct: 1348 AAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAG 1407 Query: 561 PRGLPGLPGVPGMPGPKGPPGPPG 584 RG PG PG G PG G PG G Sbjct: 1408 ERGHPGAPGPSGSPGLPGVPGSMG 1431 Score = 129 bits (325), Expect = 8e-30 Identities = 74/172 (43%), Positives = 92/172 (53%), Gaps = 18/172 (10%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP---------IGPAG 491 +QG PGP G RG +G QG PG G G +G G GPPGP GE+G GP G Sbjct: 778 VQGEPGPPG-RGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVG 836 Query: 492 PPGE--RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGK-----EGLPGPQGP- 543 PPG G G G QG G RG+PG+ GP+G G+PG P + G+PG G Sbjct: 837 PPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLW 896 Query: 544 PGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQ 595 G G G PG+PGP G PG+PG+ G+PG G PG PG + + L ++ Sbjct: 897 MGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIE 948 Score = 129 bits (323), Expect = 1e-29 Identities = 83/210 (39%), Positives = 96/210 (45%), Gaps = 58/210 (27%) Query: 449 GPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPK 508 GP+G +G G GP G G+ G G PGPPG P P GPPG +G KGS G G + Sbjct: 429 GPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKE 488 Query: 509 GSRGSPGKPGPQGPSGDP------------------GPPGPPGKEGLPGP-QGPPGFQGL 549 G G PGKPG +G GDP G PGP G+ G P P +G PG QG+ Sbjct: 489 GPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGI 548 Query: 550 QGTVGEP-----------------------GVPGPRGLPGLPGVPGMPGPK--------- 577 +G GEP G PG GLPGLPG G+PG K Sbjct: 549 KGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPG-FGLPGLPGRAGVPGLKGEKGNFGEA 607 Query: 578 GPPGPPGPSGAVVPLALQN------EPTPA 601 GP G PGP G V P ++ EP PA Sbjct: 608 GPAGSPGPPGPVGPAGIKGAKGEPCEPCPA 637 Score = 124 bits (312), Expect = 2e-28 Identities = 78/215 (36%), Positives = 84/215 (39%), Gaps = 68/215 (31%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 L G PGP G G G G G G +G G++G GPPGP G+ G G G GE+G G Sbjct: 1327 LPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAG 1386 Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPG--------------------- 539 G G GS G G PGP G G PG PGP G GLPG Sbjct: 1387 MPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQE 1446 Query: 540 ------------------------PQGPPGFQGLQGTVGEPGVPGPRGLP---------G 566 G PG G G G PG PG GLP G Sbjct: 1447 IIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQG 1506 Query: 567 LPGVPGMPGPKGP--------------PGPPGPSG 587 LPGV G+PG KG PGPPGP G Sbjct: 1507 LPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQG 1541 Score = 123 bits (309), Expect = 5e-28 Identities = 77/194 (39%), Positives = 86/194 (44%), Gaps = 51/194 (26%) Query: 445 PGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI----------------G 488 PGP+GP G G GPPG G +G G G PG PG E G + G Sbjct: 903 PGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQG 962 Query: 489 PAGPPG---ERGGKGSKG-----------------------------SQGPKGSRGSPGK 516 PG E+G KG +G S+G G GSPG Sbjct: 963 QRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGL 1022 Query: 517 PGPQGPSGDPGPPGPPGKEGLPGPQ---GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGM 573 PGP G G G GPPG G PGP GPPGF G G+ G PG+ G RGL GL G G Sbjct: 1023 PGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGE 1082 Query: 574 PGPKGPPGPPGPSG 587 PGP G PG PG +G Sbjct: 1083 PGPPGQPGYPGATG 1096 Score = 123 bits (308), Expect = 7e-28 Identities = 76/173 (43%), Positives = 84/173 (48%), Gaps = 14/173 (8%) Query: 449 GPRGDRGSQG-----PPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKG 503 G GD GS G PG G G KGEKG G GPAG GP GP GP G +G KG Sbjct: 573 GASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPC 632 Query: 504 SQGPKGSRGSPGK------PGPQGPSGDPGPP--GPPGKEGLPGPQGPPGFQGLQGTVGE 555 P S G PGP G G+PGPP G PGK+G G +G G +G G G+ Sbjct: 633 EPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGD 692 Query: 556 PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 PG PG G PGL G PG+ GP GP G G P +LQ T G P Sbjct: 693 PGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACP-SLQGTVTDMAGRPGQP 744 Score = 123 bits (308), Expect = 7e-28 Identities = 88/239 (36%), Positives = 100/239 (41%), Gaps = 93/239 (38%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG------PA------ 490 G PG G G G +G G G G G G PGP GPAG +G G PA Sbjct: 584 GLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQD 643 Query: 491 ------------------GPP-----------GERGGKGSKGSQGPKGSRGSP------- 514 GPP GERG KG KG G G G+P Sbjct: 644 GDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPG 703 Query: 515 --GKPGPQGPS---------------------------GDPGP-----------PGPPGK 534 G+PG QGP+ G PGP PG PG+ Sbjct: 704 LSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQ 763 Query: 535 EGLPGPQGPPGFQGLQGTVGEP--GVPGPR---GLPGLPGVPGMPGPKGPPGPPGPSGA 588 GLPG QGPPG +G+QG G P GV GP+ G PGLPG+ G+PGP+GPPGP G GA Sbjct: 764 PGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGA 822 Score = 122 bits (307), Expect = 9e-28 Identities = 82/230 (35%), Positives = 93/230 (40%), Gaps = 84/230 (36%) Query: 442 QGPPG---PRGPRGDRGSQGPPGPTG---------------------------------- 464 QGPPG P GP G G QG PG G Sbjct: 906 QGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRA 965 Query: 465 ------NKGQKGEKGEPGPPG-----------------------PAGERGPIGPAGPPGE 495 KG+KG++G PG PG G+ G +G G PG Sbjct: 966 HPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGP 1025 Query: 496 RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL---------------PGP 540 G G +G +GP G RGSPG PGP GP G PG G PG GL PGP Sbjct: 1026 PGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGP 1085 Query: 541 QGPPGFQGLQGTVGEPGVPGPRGLPGL---PGVPGMPGPKGPPGPPGPSG 587 G PG+ G G G PG+ G RG G G PG PG +G PGPPGP+G Sbjct: 1086 PGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAG 1135 Score = 110 bits (276), Expect = 4e-24 Identities = 72/177 (40%), Positives = 82/177 (46%), Gaps = 31/177 (17%) Query: 444 PPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP-------IGPAGP---- 492 PP G R + P GP KG KGE+G PGPPG GE+G I P P Sbjct: 317 PPCVHGARDSNVTLAPSGP---KGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCA 373 Query: 493 PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552 G +G KG G+ GP G GS G+ G +G GD G G PGK G G G G +G Sbjct: 374 EGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQ 433 Query: 553 VGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609 G+PG GP GL G PG PPG PGP G +P P D G PP Sbjct: 434 KGDPGFVGPEGLAGEPG---------PPGLPGPPGIGLP--------GTPGDPGGPP 473 Score = 88.6 bits (218), Expect = 2e-17 Identities = 57/133 (42%), Positives = 63/133 (47%), Gaps = 7/133 (5%) Query: 455 GSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP---PGERGGKGSKGSQGPKGSR 511 G GPPG G G+ G G PG PG G G G G PG +G KG G G G Sbjct: 1473 GRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGI-GIAGEN 1531 Query: 512 GSPGKPGPQGPS--GDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRG-LPGLP 568 G PG PGPQGP G G GP G++G+PG GPPG G G G G +P Sbjct: 1532 GLPGPPGPQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQ 1591 Query: 569 GVPGMPGPKGPPG 581 P M KGP G Sbjct: 1592 QYPPMKTMKGPFG 1604 Score = 83.6 bits (205), Expect = 6e-16 Identities = 51/129 (39%), Positives = 63/129 (48%), Gaps = 17/129 (13%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPA--------G 491 GPPG G G G+ G PG G G++G +G PG PG GE+G IG G Sbjct: 1476 GPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPG 1535 Query: 492 PPGERG--GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKE----GLPGPQGPPG 545 PPG +G G G G+ GP G +G PG PGP GP G PG G +P Q P Sbjct: 1536 PPGPQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPP 1595 Query: 546 FQGLQGTVG 554 + ++G G Sbjct: 1596 MKTMKGPFG 1604 Score = 55.8 bits (133), Expect = 1e-07 Identities = 33/76 (43%), Positives = 38/76 (50%), Gaps = 11/76 (14%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP-------P 493 L GPPGP+GP G G G TG GQ+G G PGPPGP G+ G G P P Sbjct: 1533 LPGPPGPQGPPG----YGKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMP 1588 Query: 494 GERGGKGSKGSQGPKG 509 E+ K +GP G Sbjct: 1589 MEQQYPPMKTMKGPFG 1604 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 172 bits (435), Expect = 1e-42 Identities = 83/158 (52%), Positives = 94/158 (59%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PGP GP G RG GP GP G +G+KG KGE G GP G+ GPIGP G PG+ G G + Sbjct: 1381 GEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLR 1440 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G GP G +G PG PGP GP G GPPG PG +G GP+G G GL G +G PG G + Sbjct: 1441 GIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEK 1500 Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP 600 G GLPG G GPKG G GPSG + P P P Sbjct: 1501 GDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGP 1538 Score = 169 bits (429), Expect = 7e-42 Identities = 86/174 (49%), Positives = 97/174 (55%), Gaps = 27/174 (15%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI---GPAGPPGERG 497 L G GP GP+G+RG +G GP+G G G KG PG GP G GP+ G GPPGE G Sbjct: 1295 LPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPG 1354 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGE-- 555 G G G KG G PG+ G GP+G+PGP GPPGK G PGP GP G QG +G GE Sbjct: 1355 PAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAG 1414 Query: 556 ----------------PGVPGPRGLPGLP------GVPGMPGPKGPPGPPGPSG 587 PG PGP GL G+P G+PG PGP GPPGP GP G Sbjct: 1415 LEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPG 1468 Score = 169 bits (427), Expect = 1e-41 Identities = 93/211 (44%), Positives = 103/211 (48%), Gaps = 48/211 (22%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP------PG 494 L GP GP GP G+ G +G G G KG KG+KGE GPPGP G +GPIG GP PG Sbjct: 1142 LPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPG 1201 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGP---------------------QGPSGDPGPPGPPG 533 RG +G G +G +G RG PG PGP GP G PGP GP G Sbjct: 1202 PRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSG 1261 Query: 534 KEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLP---------------------GVPG 572 G GPQGPPG G G VGE G PG G PGLP G G Sbjct: 1262 APGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAG 1321 Query: 573 MPGPKGPPGPPGPSGAVVPLALQNEPTPAPE 603 PGPKGPPG GP G+ P+ +P P E Sbjct: 1322 PPGPKGPPGDDGPKGSPGPVGFPGDPGPPGE 1352 Score = 166 bits (419), Expect = 9e-41 Identities = 91/203 (44%), Positives = 103/203 (50%), Gaps = 45/203 (22%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP---------- 492 GP G RGP G RG +GP G TG G KG G GP GP GERGP GP GP Sbjct: 907 GPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPP 966 Query: 493 --------PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD---------PGPPGPPGKE 535 PG G +G G QG G G PG GPQGP+G+ PGPPGPPG++ Sbjct: 967 GPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQ 1026 Query: 536 GLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGP---------KGPPGPP--- 583 GLPG G G +G G G PG GP GL G PG G+PGP +GPPGPP Sbjct: 1027 GLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPA 1086 Query: 584 ------GPSGAVVPLALQNEPTP 600 GP+GA P+ + P P Sbjct: 1087 GSPGERGPAGAAGPIGIPGRPGP 1109 Score = 165 bits (417), Expect = 2e-40 Identities = 83/151 (54%), Positives = 94/151 (62%), Gaps = 3/151 (1%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPA---GERGPIGPAGPPGERG 497 L G GP G RG G +G PGP G G KG +G PGPPGPA GERGP G AGP G G Sbjct: 1046 LPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPG 1105 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557 G +G GP G +G+PG+ GPQGP+G G GP G G GP GPPG G +G +GEPG Sbjct: 1106 RPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPG 1165 Query: 558 VPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588 G +G G G PG GP+GP G PGPSGA Sbjct: 1166 QKGSKGDKGEQGPPGPTGPQGPIGQPGPSGA 1196 Score = 165 bits (417), Expect = 2e-40 Identities = 92/182 (50%), Positives = 99/182 (54%), Gaps = 36/182 (19%) Query: 443 GPPGPRGPRGDRGS---------------QGPPGPTGNKGQKGEKGEPGPPG------PA 481 GPPGP G G+RG QGPPGP G KG GEKG GP G P Sbjct: 1081 GPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPV 1140 Query: 482 GERGPIGPAGPPGERGGKGS------KGSQGPKGSRGSPGKPGPQGPSGDPGP------P 529 G GP GP GPPGE G KG KGS+G KG +G PG GPQGP G PGP P Sbjct: 1141 GLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEP 1200 Query: 530 GPPGKEGL---PGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPS 586 GP G++GL G +GP GF G G VG G+PGP G G G G GP GPPGP GPS Sbjct: 1201 GPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPS 1260 Query: 587 GA 588 GA Sbjct: 1261 GA 1262 Score = 164 bits (416), Expect = 2e-40 Identities = 90/197 (45%), Positives = 101/197 (51%), Gaps = 34/197 (17%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---------------------PGPA 481 GPPGP+GP GD G +G PGP G G G GEPGP PGP Sbjct: 1321 GPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPT 1380 Query: 482 GERGPIGPAG------PPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKE 535 GE GP GP G P G G +G KG++G G G PGK GP GP G PG PGP G Sbjct: 1381 GEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLR 1440 Query: 536 GLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQ 595 G+PGP G QGL G+ G G PGP G PGLPG+ G GPKG G PG G + P Q Sbjct: 1441 GIPGPVGE---QGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQ 1497 Query: 596 NEP----TPAPEDNGCP 608 E P P+ + P Sbjct: 1498 GEKGDRGLPGPQGSSGP 1514 Score = 163 bits (413), Expect = 5e-40 Identities = 84/163 (51%), Positives = 96/163 (58%), Gaps = 15/163 (9%) Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE------PGPPGPAGERGPIGP 489 + F L G PG +G RGD G GPPGP G+ G++G+ GE PG PGP G GP GP Sbjct: 630 RGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGP 689 Query: 490 AGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQ---GPPGF 546 GPPG G G G GPKG+ G G+PGP PG G PG +GLPGPQ GPPG Sbjct: 690 PGPPGPPGVTGMDGQPGPKGNVGPQGEPGP------PGQQGNPGAQGLPGPQGAIGPPGE 743 Query: 547 QGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAV 589 +G G G PG+PG G PG PG G PG KG GPPGP G + Sbjct: 744 KGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPI 786 Score = 163 bits (412), Expect = 6e-40 Identities = 88/187 (47%), Positives = 99/187 (52%), Gaps = 27/187 (14%) Query: 441 LQGPPGP------RGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG 494 +QGPPGP RG G G++G PG TG KG +G G G PG G RG GP+GPPG Sbjct: 596 VQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPG 655 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQG---PSGDPGPPGPPGKEGL-------------- 537 G G +G G G RG PG+PGP+G P G PGPPGPPG G+ Sbjct: 656 PPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQG 715 Query: 538 ----PGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLA 593 PG QG PG QGL G G G PG +G G PG+PGMPG GPPG PG G Sbjct: 716 EPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKG 775 Query: 594 LQNEPTP 600 Q P P Sbjct: 776 GQGPPGP 782 Score = 162 bits (411), Expect = 8e-40 Identities = 87/174 (50%), Positives = 98/174 (56%), Gaps = 18/174 (10%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GP G GP GD+G G PG TG+ G GE PGP GP G+RGP GPAGP G +G KG+K Sbjct: 1354 GPAGQDGPPGDKGDDGEPGQTGSPGPTGE---PGPSGPPGKRGPPGPAGPEGRQGEKGAK 1410 Query: 503 GSQG---------PKGSRGSPGKPGPQGPSGDPGP------PGPPGKEGLPGPQGPPGFQ 547 G G P G +G+PGKPGP G G PGP PG PG +G PGP GPPG Sbjct: 1411 GEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLP 1470 Query: 548 GLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601 GL+G G G G GL GL G PG G KG G PGP G+ P Q P+ Sbjct: 1471 GLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPS 1524 Score = 160 bits (404), Expect = 5e-39 Identities = 84/177 (47%), Positives = 99/177 (55%), Gaps = 11/177 (6%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE---PGPPGPAGERGPIGPAGPPGERGGK 499 G PGP GP G++G G PG G G++G KG PG PG GE+G G G PG RG + Sbjct: 853 GDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQR 912 Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559 G G +G +G RG GKPGP+G SG GP GPPG+ G GPQGP GF G +G G PG Sbjct: 913 GPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKD 972 Query: 560 GPRGLPGLPGVPGMPGPKGPPGPP------GPSGAVVPLALQNEPTP--APEDNGCP 608 G G PG G G G GPPGPP GP+G P+ + P P P + G P Sbjct: 973 GLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLP 1029 Score = 159 bits (403), Expect = 7e-39 Identities = 83/170 (48%), Positives = 96/170 (56%), Gaps = 4/170 (2%) Query: 442 QGP---PGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498 QGP PGP+GP G G G PG G +G+ G +G+ GPPGP G GP GP G G G Sbjct: 954 QGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGE 1013 Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV 558 +G G GP G +G PG G +G GDPGP G PGK+G PG +G PG +GL G VG G+ Sbjct: 1014 RGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGL 1073 Query: 559 PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 G G PG PG G PG +GP G GP G Q P PA E G P Sbjct: 1074 KGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGE-KGAP 1122 Score = 159 bits (401), Expect = 1e-38 Identities = 85/171 (49%), Positives = 98/171 (57%), Gaps = 16/171 (9%) Query: 446 GPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQ 505 GP GP G G GP GP G+ G KGE G+ GP GP G +GP GPAG PG RG GS G+ Sbjct: 559 GPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGA- 617 Query: 506 GPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL---PGPQGPPGFQGLQGTVGEPGVPGPR 562 RG PG+ GP+G G G G PG++G PGP GPPG G G G+ G GPR Sbjct: 618 -----RGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPR 672 Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP----APEDNGCPP 609 GLPG PG G+ GPKGPPGPPGP G + +P P P+ PP Sbjct: 673 GLPGEPGPRGLLGPKGPPGPPGPPGVT---GMDGQPGPKGNVGPQGEPGPP 720 Score = 157 bits (396), Expect = 4e-38 Identities = 90/198 (45%), Positives = 98/198 (49%), Gaps = 34/198 (17%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP------PGPAGERGPIGPAGPPG 494 L G PG +GP+G G G PG G KG +G G+PGP GP GERGP G G PG Sbjct: 872 LPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPG 931 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLP---------------G 539 +G G G GP G RG G GP G G GPPGPPGK+GLP G Sbjct: 932 PKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 991 Query: 540 PQGPPGFQGLQGTVGE---------PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVV 590 P GPPG G QG GE PG PGP G GLPG+ G G KG PGP G G Sbjct: 992 PPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDG 1051 Query: 591 PLALQNEPTPAPEDNGCP 608 P L+ P D G P Sbjct: 1052 PPGLRG----FPGDRGLP 1065 Score = 154 bits (390), Expect = 2e-37 Identities = 82/177 (46%), Positives = 90/177 (50%), Gaps = 6/177 (3%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI------GPAGPPGE 495 +GP G GP G G QG PGP G KG+ G+ G+ GPPGP G RGP GP GPPG Sbjct: 1215 EGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGG 1274 Query: 496 RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGE 555 G G+ G +G G G PG PG GP G G G G+ G G GPPG +G G G Sbjct: 1275 IGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGP 1334 Query: 556 PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPPHWK 612 G PGP G PG PG PG PGP G GPPG G P P E P K Sbjct: 1335 KGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGK 1391 Score = 154 bits (390), Expect = 2e-37 Identities = 84/169 (49%), Positives = 95/169 (56%), Gaps = 10/169 (5%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKG---QKGEKGEPGPPGPAGERGPIGPAGPPGERG 497 L+GPPG GP G +G+ G PGP G +G GE+G PG PGP G GP+GP G PG +G Sbjct: 1415 LEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKG 1474 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557 G KG +G G G G PG QG GD G PGP G G G QG G G G G PG Sbjct: 1475 DSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPG 1534 Query: 558 VPGPRGLPGLPGVPGMPGPK------GPPGPPGPSGAVV-PLALQNEPT 599 +PGP G G G G GPK GPPGPPGP G V+ PL +Q T Sbjct: 1535 LPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLPIQASRT 1583 Score = 154 bits (388), Expect = 4e-37 Identities = 86/181 (47%), Positives = 97/181 (53%), Gaps = 24/181 (13%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 L GP G G +G+ G GPPGP G+ G++G G GP G G GP GP GP GE+G G Sbjct: 1064 LPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPG 1123 Query: 501 SKGSQGPKGS---RGSPGKPGPQGPSGDP---------GPPGPPGKEGLPGPQGPPGFQG 548 KG QGP G +G G PGP GP G P G PG G +G G QGPPG G Sbjct: 1124 EKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTG 1183 Query: 549 LQGTVGEP------GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAP 602 QG +G+P G PGPRG GL G G GP+G PGPPGP G LQ P P Sbjct: 1184 PQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVG------LQGLPGPPG 1237 Query: 603 E 603 E Sbjct: 1238 E 1238 Score = 153 bits (387), Expect = 5e-37 Identities = 79/160 (49%), Positives = 92/160 (57%), Gaps = 9/160 (5%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGE------KGEPGPPGPAGERGPIGPAGPPG 494 L+G PG GP+G RG QGPPGP G G++G +G PG GP G+RG G AG PG Sbjct: 581 LKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPG 640 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVG 554 E+G +G G GP G G G+ G G G G PG PG GL GP+GPPG G G G Sbjct: 641 EKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTG 700 Query: 555 EPGVPGPRGLPGLPGVPGMPGPKGPPGP---PGPSGAVVP 591 G PGP+G G G PG PG +G PG PGP GA+ P Sbjct: 701 MDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGP 740 Score = 153 bits (386), Expect = 6e-37 Identities = 82/179 (45%), Positives = 99/179 (55%), Gaps = 12/179 (6%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGN------KGQKGEKGEPGPPGPAGERGPIGPAGPPGER 496 G PG GP G++G QGPPGP G +G KG G G G GE+G G G G+ Sbjct: 763 GHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDM 822 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQG---PSGDPGPPGPPGKEG---LPGPQGPPGFQGLQ 550 G KG +G GP G RG G GP+G P+GDPGP GPPG++G +PG G PG QG + Sbjct: 823 GIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPK 882 Query: 551 GTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609 G++G PG PG G G G PG PGP+G GP GP G P + +P P G P Sbjct: 883 GSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGP 941 Score = 153 bits (386), Expect = 6e-37 Identities = 88/199 (44%), Positives = 104/199 (52%), Gaps = 39/199 (19%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKG------QKGEKGEPGPPGPAGERGPIGPAGPPGE 495 QGP G GP G+RG GPPGP G +G ++G KG+PGP G G+ GP G G PG+ Sbjct: 1002 QGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGD 1061 Query: 496 RGGKGSKGSQGPKGSRGSPGKPGPQGPSGD------------------PGPPGPPGKEGL 537 RG G G+ G KG+ G PG PGP G G+ GPPGP G++G Sbjct: 1062 RGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGA 1121 Query: 538 PG---PQGPPGFQGLQGTVGEPGVPGPRGLP---------GLPGVPGMPGPKGPPGPPGP 585 PG PQGP G GLQG VG PG GP G P G PG G G KG GPPGP Sbjct: 1122 PGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGP 1181 Query: 586 SGAVVPLALQNEPTPAPED 604 +G P+ +P P+ D Sbjct: 1182 TGPQGPI---GQPGPSGAD 1197 Score = 153 bits (386), Expect = 6e-37 Identities = 79/159 (49%), Positives = 86/159 (54%), Gaps = 12/159 (7%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG---ERGPIGPAGPPGERG 497 L GPPG +G GD G GPPGP G +G G G GP GP G G +G G PGE G Sbjct: 1232 LPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAG 1291 Query: 498 GKGSKGS---QGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVG 554 G G GPKG RG G+ GP G +G PGP GPPG +G G GP GF G G G Sbjct: 1292 EPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPG 1351 Query: 555 EP------GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 EP G PG +G G PG G PGP G PGP GP G Sbjct: 1352 EPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPG 1390 Score = 152 bits (384), Expect = 1e-36 Identities = 82/175 (46%), Positives = 95/175 (54%), Gaps = 10/175 (5%) Query: 443 GPPGPRGPRG---------DRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPP 493 G PGPRG +G RG GPPGP G +G G GE G G G+ GP GP GP Sbjct: 1198 GEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPR 1257 Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553 G G G+ G QGP G G+PG G +G G+ G PG PG+ G PGP+G G +G G Sbjct: 1258 GPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPS 1317 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 G G PGP+G PG G G PGP G PG PGP G P A Q+ P D+G P Sbjct: 1318 GAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGP-AGQDGPPGDKGDDGEP 1371 Score = 150 bits (379), Expect = 4e-36 Identities = 83/173 (47%), Positives = 93/173 (53%), Gaps = 24/173 (13%) Query: 439 TILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPP---------GPAGERGPIGP 489 T QG GP GP G G QGP G TG G++G G PGPP G G +G GP Sbjct: 984 TGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGP 1043 Query: 490 A------GPPGERGGKGSKGSQGPKGS---RGSPGKPGPQGPSGDPGPPGPPGK------ 534 A GPPG RG G +G GP G+ +G+ G PGP GP+G PG GP G Sbjct: 1044 AGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGI 1103 Query: 535 EGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G PGPQGPPG G +G GE G GP G GL G G+PGP GP GPPG G Sbjct: 1104 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDG 1156 Score = 149 bits (376), Expect = 9e-36 Identities = 85/186 (45%), Positives = 96/186 (51%), Gaps = 23/186 (12%) Query: 441 LQGPPGPRGPRGDRGSQGPPGP---------TGNKGQKGEKGEPGPPGPAGERGPIGPAG 491 L G PG RG G +G GPPGP TG G GE+G PGPPGP GE+G G AG Sbjct: 974 LPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAG 1033 Query: 492 PPGERGGKGSKG---SQGPKGSRGSPGKPGPQGP------SGDPGPPGPPGKEGLPGPQG 542 G +G G G GP G RG PG G GP G+ GPPGPPG G PG +G Sbjct: 1034 KEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERG 1093 Query: 543 PPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNE--PTP 600 P G G +G PG PGP+G PG G G PG KGP GP G G P+ L P Sbjct: 1094 P---AGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVG 1150 Query: 601 APEDNG 606 P ++G Sbjct: 1151 PPGEDG 1156 Score = 115 bits (288), Expect = 1e-25 Identities = 89/250 (35%), Positives = 98/250 (39%), Gaps = 95/250 (38%) Query: 446 GPRGPRG-DRGSQGPPGPTGNKGQKGE----------KGEPGP------PGPAGERGPIG 488 GP P D +G GP G KGQKGE +G PGP PGP G GP G Sbjct: 431 GPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTG 490 Query: 489 PAGPPGER----------------------------GGKGSKGS---------------- 504 G PGER GG G GS Sbjct: 491 QVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAIL 550 Query: 505 -------QGPKGSRGSPGKPGPQGP---------SGDPGPPGPPGKEGLPGPQGPPGFQG 548 +GP G G G+PGP GP GD GP GP G +G PGP G PG +G Sbjct: 551 QQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRG 610 Query: 549 LQGTVGEPGVP------GPRGLPGLPGVPGM------PGPKGPPGPP------GPSGAVV 590 G+ G G+P G RG GL G+PG PGP GPPGPP G G V Sbjct: 611 RAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVG 670 Query: 591 PLALQNEPTP 600 P L EP P Sbjct: 671 PRGLPGEPGP 680 Score = 80.9 bits (198), Expect = 4e-15 Identities = 45/100 (45%), Positives = 52/100 (52%), Gaps = 6/100 (6%) Query: 480 PAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSG-DPGPPGPPGKEGLP 538 P IGP P + +G GP+G +G G+P P GPPGP G GLP Sbjct: 423 PTSSPSEIGPGMPANQ--DTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLP 480 Query: 539 GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKG 578 GP PG G G VG+PG GP G PGLPG G+PGP G Sbjct: 481 GP---PGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPG 517 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 171 bits (432), Expect = 3e-42 Identities = 82/145 (56%), Positives = 88/145 (60%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GPPGP G G G G PG G +G GEKGE GPPG AG G GPAGPPG +G KG + Sbjct: 804 GPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGER 863 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 GS G G+ G PG G GP G G PGPPG G PG GPPG G G G PGV GP+ Sbjct: 864 GSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPK 923 Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSG 587 G G PG G PG +GPPG PGP G Sbjct: 924 GDAGQPGEKGSPGAQGPPGAPGPLG 948 Score = 168 bits (426), Expect = 1e-41 Identities = 82/151 (54%), Positives = 90/151 (59%), Gaps = 6/151 (3%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKG------EPGPPGPAGERGPIGPAGPPGER 496 GP GPRG G+ G G PG G +G G G +PGPPG GE G GP GP G R Sbjct: 513 GPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPR 572 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G G G GPKG+ G+PGK G +G G PGP GPPGK G GPQGPPG G G G+ Sbjct: 573 GQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDT 632 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G PGP+GL GLPG G PG G PG PGP G Sbjct: 633 GPPGPQGLQGLPGTGGPPGENGKPGEPGPKG 663 Score = 165 bits (417), Expect = 2e-40 Identities = 82/155 (52%), Positives = 90/155 (58%), Gaps = 9/155 (5%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 QGPPGP GP GD+G GPPGP G +G G G PG G GE GP G AG PG GGKG Sbjct: 617 QGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGD 676 Query: 502 KGSQGPKGS---------RGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552 G+ G +G RG G PGP+G G GPPGPPG G PG QG PG +G G+ Sbjct: 677 AGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGS 736 Query: 553 VGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G G G G PG GVPG GP+GP GP GP G Sbjct: 737 PGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPG 771 Score = 163 bits (413), Expect = 5e-40 Identities = 90/183 (49%), Positives = 98/183 (53%), Gaps = 17/183 (9%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE------PGPPGPAGERGPIGPAGPPGER 496 GPPGP GPRG G G PGP GN G G+ GE PGP GP G+ G GP GPPG Sbjct: 564 GPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPT 623 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G G KG GP G +G G PG GP G+ G PG PG +G G G PG +G G GE Sbjct: 624 GPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGER 683 Query: 557 GVPGPRGLPGLPGVPGMPGP---KGPPGPPGPSGAVVPLALQNEP-------TPAPE-DN 605 G PG G PGL G G PGP KG GPPGP GA LQ P +P P+ D Sbjct: 684 GPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDK 743 Query: 606 GCP 608 G P Sbjct: 744 GEP 746 Score = 162 bits (409), Expect = 1e-39 Identities = 82/152 (53%), Positives = 88/152 (57%), Gaps = 12/152 (7%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG------ERGPIGPAGPPGER 496 G PG GPRG G GPPGP G G KGE G PG PG AG ERG GP GP G Sbjct: 753 GVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFP 812 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G G G G KG RG+PG+ G GP G GPPG G P GPPG QG++G G P Sbjct: 813 GAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSG------PAGPPGPQGVKGERGSP 866 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588 G PG G PG G+PG PG G PGPPGPSG+ Sbjct: 867 GGPGAAGFPGARGLPGPPGSNGNPGPPGPSGS 898 Score = 158 bits (400), Expect = 2e-38 Identities = 80/155 (51%), Positives = 91/155 (58%), Gaps = 12/155 (7%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PGP+GP G G GP GP G G G+KG+ GPPGP G +G G GPPGE G Sbjct: 600 GGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENG---KP 656 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQG---PPGFQGLQGTVGEPGVP 559 G GPKG G+PG PG +G +G PG GPPG G PG +G PPG +G +G G PG P Sbjct: 657 GEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPP 716 Query: 560 GPRGLPGLPGVPG------MPGPKGPPGPPGPSGA 588 G G PGL G+PG PGPKG G PG GA Sbjct: 717 GAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGA 751 Score = 158 bits (399), Expect = 2e-38 Identities = 83/164 (50%), Positives = 92/164 (56%), Gaps = 15/164 (9%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP------PGPAGER------GPIGPA 490 G PGP G +G+ G GPPGP+G +GQ G G PGP PG GER GP GP Sbjct: 549 GKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPP 608 Query: 491 GPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDP---GPPGPPGKEGLPGPQGPPGFQ 547 G GE G +G G GP G +G G PGPQG G P GPPG GK G PGP+G G Sbjct: 609 GKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAP 668 Query: 548 GLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 G G G+ G PG RG PGL G PG+ G GPPGP G GA P Sbjct: 669 GAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGP 712 Score = 157 bits (398), Expect = 3e-38 Identities = 83/170 (48%), Positives = 93/170 (54%), Gaps = 27/170 (15%) Query: 443 GPPGPRGPRGDRGSQG---------PPGPTGNKGQKGEKGEPGP------PGPAGERGPI 487 G PG +G RG+ GS G PPGP G G+ G++GE GP PGPAG RG Sbjct: 1026 GSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAP 1085 Query: 488 GPAGPPGERGGKGSKGSQGPKGSR------GSPGKPGPQGPSGDPGPPGPPGKEGLPGPQ 541 GP GP G++G G +G+ G KG R G+PG PGP G G G PGP G G GP Sbjct: 1086 GPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPS 1145 Query: 542 GPPGFQGLQGTVGEPGVPGP------RGLPGLPGVPGMPGPKGPPGPPGP 585 GPPG G G G G PGP RG G PG PG PGP GPPG PGP Sbjct: 1146 GPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGP 1195 Score = 155 bits (392), Expect = 1e-37 Identities = 80/172 (46%), Positives = 92/172 (53%), Gaps = 27/172 (15%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKG------EKGEPGPPGPAGERGPIGPAGPPGER 496 GPPGP+G +G+RGS G PG G G +G G PGPPGP+G G GP GP G Sbjct: 852 GPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNT 911 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP------------PGKEGLPGPQGPP 544 G GS G GPKG G PG+ G G G PG PGP G G+PGP+G P Sbjct: 912 GAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSP 971 Query: 545 GFQGLQGTVGEPGV---------PGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G QG++G G+PG PGP+GLPGL G G PG G PG G G Sbjct: 972 GPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPG 1023 Score = 154 bits (389), Expect = 3e-37 Identities = 88/185 (47%), Positives = 96/185 (51%), Gaps = 27/185 (14%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERG----- 497 GPPGP G G GS G GP G+ GQ GEKG PG GP G GP+G AG G RG Sbjct: 903 GPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPP 962 Query: 498 -GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL------PGPQGPPGFQGLQ 550 G +GS GP+G +G GKPG G SG+ GPPGP G GL PG G PG GL Sbjct: 963 GMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLP 1022 Query: 551 GTVGEPGVPGPRG------LPGLPGVPGMPGPKGP---------PGPPGPSGAVVPLALQ 595 G G PG G RG PG PG PG PGP GP GP GP+GA P + Sbjct: 1023 GRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSR 1082 Query: 596 NEPTP 600 P P Sbjct: 1083 GAPGP 1087 Score = 152 bits (385), Expect = 8e-37 Identities = 84/187 (44%), Positives = 91/187 (48%), Gaps = 36/187 (19%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERG--- 497 L GPPG GPRG G QG G +G G G GE GPPGP G G G AG PG G Sbjct: 958 LAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPG 1017 Query: 498 ------------GKGSKGSQGPKGSRGSPGKPGP---------------QGPSGDPGPPG 530 GKG +G G G+ G+PG PGP GP+G G PG Sbjct: 1018 SDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPG 1077 Query: 531 PPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPK------GPPGPPG 584 P G G PGPQGP G +G G G G+ G RG PG PG PG PGP G PGP G Sbjct: 1078 PAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAG 1137 Query: 585 PSGAVVP 591 P G V P Sbjct: 1138 PRGPVGP 1144 Score = 152 bits (384), Expect = 1e-36 Identities = 79/151 (52%), Positives = 86/151 (56%), Gaps = 15/151 (9%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GPPG GP G G GPPGP G KGE+G PG PG AG G G GPP GS Sbjct: 837 GPPGVAGPPGGSGPAGPPGPQ---GVKGERGSPGGPGAAGFPGARGLPGPP------GSN 887 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G+ GP G GSPGK GP GP+G+ G PG PG G G G PG +G G G PG PGP Sbjct: 888 GNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPL 947 Query: 563 GLP------GLPGVPGMPGPKGPPGPPGPSG 587 G+ GL G PGMPGP+G PGP G G Sbjct: 948 GIAGITGARGLAGPPGMPGPRGSPGPQGVKG 978 Score = 152 bits (383), Expect = 1e-36 Identities = 85/187 (45%), Positives = 95/187 (50%), Gaps = 23/187 (12%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G G RGP G G+ G PG G G+ G+ G G PGP GERG G G PG +G G Sbjct: 408 GLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKD 467 Query: 503 GSQGPKGS---------RGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553 GS G G+ RG+PG GP GP+G PG GP G+ G PGP GP G G G Sbjct: 468 GSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRD 527 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGP---------PGPPGPSGAVVPLALQNEPTP---- 600 G PG PG RG+PG PG PG G GP PGPPGPSG + P P Sbjct: 528 GVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGND 587 Query: 601 -APEDNG 606 AP NG Sbjct: 588 GAPGKNG 594 Score = 151 bits (381), Expect = 2e-36 Identities = 82/161 (50%), Positives = 92/161 (57%), Gaps = 21/161 (13%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERG------PIGPAGP 492 +G PGPRG RG+ G G PG G G+ G GEPG PG AGERG P GP G Sbjct: 440 KGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGI 499 Query: 493 PGERGGKGSKGSQGPKGSRGSPGKPG----PQGPS--GDPGPPGPPGKEGLPGPQGPPGF 546 PGE+G G +G+ GP G RG+ G+PG P GP G PG PG PG +G PGP G Sbjct: 500 PGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGS--- 556 Query: 547 QGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 QG G PG PGP G G PGV G PGPKG G PG +G Sbjct: 557 ---QGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNG 594 Score = 151 bits (381), Expect = 2e-36 Identities = 81/172 (47%), Positives = 88/172 (51%), Gaps = 27/172 (15%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGN---------KGQKGEKGEPGPPGPAGERGPIGPAGPP 493 G PGP GP G G GPPGP GN G KG+ G+PG G G +GP G GP Sbjct: 888 GNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPL 947 Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553 G G G++G GP G G G PGPQG G+ G PG G G GP GP G GL GT Sbjct: 948 GIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTA 1007 Query: 554 GEP---GVPGPRGLP---------------GLPGVPGMPGPKGPPGPPGPSG 587 GEP G PG GLP G PG PG PG GPPGP GP+G Sbjct: 1008 GEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAG 1059 Score = 150 bits (380), Expect = 3e-36 Identities = 87/209 (41%), Positives = 99/209 (47%), Gaps = 54/209 (25%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG------------PPGPAGERGPIGPA 490 G PG GP+GD G+ G PG G+ G GE+G PG PPGP G +G GP Sbjct: 654 GKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPP 713 Query: 491 GPPG------------ERGGKGSKGSQGPKGSRGSPG------KPGPQGPSGDPGPPGP- 531 GPPG ERGG GS G +G KG G PG K GP+GP+G GPPGP Sbjct: 714 GPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPA 773 Query: 532 -----------------------PGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLP 568 PG+ G GP GP GF G G GEPG G RG PG Sbjct: 774 GQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEK 833 Query: 569 GVPGMPGPKGPPGPPGPSGAVVPLALQNE 597 G G PG GPPG GP+G P ++ E Sbjct: 834 GEGGPPGVAGPPGGSGPAGPPGPQGVKGE 862 Score = 149 bits (376), Expect = 9e-36 Identities = 86/183 (46%), Positives = 99/183 (54%), Gaps = 16/183 (8%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG---------PIGPAG 491 L GPPG +GP G G G G G G+ GEKGE G PG GE G P+GP G Sbjct: 244 LPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRG 303 Query: 492 PPGERGGKG---SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG 548 PGERG G + G++G G+RGS G+PGP GP G G PG PG +G GP G PG G Sbjct: 304 APGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNG 363 Query: 549 LQGTVGEPGV---PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDN 605 G GEPG G +G PG PG+ G PG KG GP G GA + + P PA N Sbjct: 364 APGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGA-N 422 Query: 606 GCP 608 G P Sbjct: 423 GAP 425 Score = 149 bits (376), Expect = 9e-36 Identities = 78/168 (46%), Positives = 86/168 (51%), Gaps = 6/168 (3%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GP GPRG G+RG G PG G +G G +G G PGP G G G G PG +G G Sbjct: 297 GPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPA 356 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLP------GPQGPPGFQGLQGTVGEP 556 GS G G+ G G+PGPQG +G GPPGPPG G P GP G PG GL G G P Sbjct: 357 GSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPP 416 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPED 604 G G G PGL G G PG G G PGP G + P ED Sbjct: 417 GPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGED 464 Score = 146 bits (368), Expect = 8e-35 Identities = 85/207 (41%), Positives = 96/207 (46%), Gaps = 26/207 (12%) Query: 428 DSKHGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI 487 D K G + GP GP GP G G+ G PG G+ G +G GEPG GP+G GP Sbjct: 159 DVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPP 218 Query: 488 GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQ 547 G GP G G G G G G RG PG PG +GP+G PG PG G G G G G Sbjct: 219 GAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGET 278 Query: 548 GLQGTVGEPGVP---------GPRGLPGLPGVPGMP---------------GPKGPPGPP 583 G G GE G+P GPRG PG G PG+P G GPPGPP Sbjct: 279 GAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPP 338 Query: 584 GPSGAVVPLALQNEPTPA--PEDNGCP 608 G +G + E PA P NG P Sbjct: 339 GTAGFPGSPGAKGEVGPAGSPGSNGAP 365 Score = 142 bits (358), Expect = 1e-33 Identities = 74/164 (45%), Positives = 83/164 (50%), Gaps = 6/164 (3%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GP GP GP G G GP G G G+ G GE G PGP G +GP G G PG +G +G Sbjct: 210 GPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFD 269 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV---- 558 G G KG G+PG G G G+ G PGP G G PG +G PG G G G G Sbjct: 270 GRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSD 329 Query: 559 --PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP 600 PGP G PG G PG PG KG GP G G+ + EP P Sbjct: 330 GQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGP 373 Score = 141 bits (356), Expect = 2e-33 Identities = 78/180 (43%), Positives = 89/180 (49%), Gaps = 21/180 (11%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GPPG G G G++G GP G+ G G G+ G PGP G G GP GPPG G G K Sbjct: 336 GPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGK 395 Query: 503 GSQGPKGSRGSPG------KPGPQGPSGDPG------PPGPPGKEGLPGPQGP------- 543 G GP G G+PG PGP G +G PG PG G +G PGP+G Sbjct: 396 GEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIP 455 Query: 544 --PGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601 PG +G G G PG PG GLPG G G PG +GP GP G G P + P PA Sbjct: 456 GVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPA 515 Score = 141 bits (355), Expect = 2e-33 Identities = 76/172 (44%), Positives = 90/172 (52%), Gaps = 21/172 (12%) Query: 435 IKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG 494 I F ++G G G G++G G PG G G GE G PGP GP RG G G PG Sbjct: 256 IPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGP---RGAPGERGRPG 312 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDP---------GPPGPPGKEGLPGPQGPPG 545 G G++G+ G +GS G PG PGP G +G P GP G PG G PG +G PG Sbjct: 313 LPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPG 372 Query: 546 FQGLQGTVGEPGVPGPRGLP---------GLPGVPGMPGPKGPPGPPGPSGA 588 QG G G PG PG G P G+PG PG+ G +GPPGP G +GA Sbjct: 373 PQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGA 424 Score = 140 bits (352), Expect = 6e-33 Identities = 85/218 (38%), Positives = 97/218 (44%), Gaps = 57/218 (26%) Query: 444 PPGPRGPRGDRGSQGPPGPTGNK------GQKGEKGEPGPP------------------- 478 PP +GP+G +G GPPG G GQ G G PGPP Sbjct: 98 PPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDS 157 Query: 479 ----------GPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGP 528 G AG GP GP GPPG G G GS G G +G PG+PG GPSG PGP Sbjct: 158 YDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGP 217 Query: 529 P---GPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGV--------------- 570 P GP G G G G PG G +G G PG+ GP G+PG PG+ Sbjct: 218 PGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGE 277 Query: 571 PGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 G PG KG G PG +GA P+ P AP + G P Sbjct: 278 TGAPGLKGENGLPGENGAPGPMG----PRGAPGERGRP 311 Score = 139 bits (351), Expect = 7e-33 Identities = 78/165 (47%), Positives = 86/165 (52%), Gaps = 18/165 (10%) Query: 441 LQGPPGPRGPRGDRGSQGPPGP------TGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG 494 L G G RG G RGS G PGP G G G KGE GP G G G G G PG Sbjct: 313 LPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPG 372 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVG 554 +G G++G GP G GSPG G GP+G PG PG G G PGP G G GL+G G Sbjct: 373 PQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAG 432 Query: 555 EP------GVPGPRGLPGLPGVPGMPGPK------GPPGPPGPSG 587 EP G PGPRG G G+PG+PG K G PG PG +G Sbjct: 433 EPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANG 477 Score = 128 bits (322), Expect = 2e-29 Identities = 76/198 (38%), Positives = 81/198 (40%), Gaps = 53/198 (26%) Query: 443 GPPGPRGPRGDRG------SQ--------------------------------------- 457 GPPG G GD G S Sbjct: 112 GPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAG 171 Query: 458 --------GPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKG 509 GPPGP G G G G PG GP GE G GP+GPPG G G G G G Sbjct: 172 YPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDG 231 Query: 510 SRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPG 569 G PG+PG +G G PG GP G G PG +G GF G G GE G PG +G GLPG Sbjct: 232 ESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPG 291 Query: 570 VPGMPGPKGPPGPPGPSG 587 G PGP GP G PG G Sbjct: 292 ENGAPGPMGPRGAPGERG 309 Score = 111 bits (277), Expect = 3e-24 Identities = 72/184 (39%), Positives = 78/184 (42%), Gaps = 47/184 (25%) Query: 445 PGPRGPRGD------RGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498 P P P G+ + P P +G +G KG+PGPPG G G G G PG Sbjct: 75 PNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPG---- 130 Query: 499 KGSKGSQGPKG--------------------------SRGSPGKPGPQGPSGDPGPPGP- 531 S GS GP G G G PGP GP G PGPPG Sbjct: 131 --SPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTS 188 Query: 532 --PGKEGLPGPQGPPGFQGLQGTVGEPGVP------GPRGLPGLPGVPGMPGPKGPPGPP 583 PG G PG QGPPG G G G PG P GP G G G PG PG +G PGPP Sbjct: 189 GHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPP 248 Query: 584 GPSG 587 G G Sbjct: 249 GIKG 252 Score = 108 bits (269), Expect = 2e-23 Identities = 53/114 (46%), Positives = 64/114 (56%), Gaps = 24/114 (21%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPG---------------PAGERGP 486 +G PGP+GPRGD+G G G G KG +G G PG PG PAG RGP Sbjct: 1082 RGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGP 1141 Query: 487 IGPAGPPGERGGKGS---------KGSQGPKGSRGSPGKPGPQGPSGDPGPPGP 531 +GP+GPPG+ G G +G++G +GS GSPG PG GP G PG PGP Sbjct: 1142 VGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGP 1195 Score = 103 bits (256), Expect = 8e-22 Identities = 63/171 (36%), Positives = 66/171 (38%), Gaps = 37/171 (21%) Query: 475 PGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGK 534 P P P GE + P P +G QGPKG G PG PG G G PG PG PG Sbjct: 75 PNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGS 134 Query: 535 -----------------------------------EGLPGPQGPPGFQGLQGTVGEPGVP 559 G PGP GPPG G GT G PG P Sbjct: 135 PGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSP 194 Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP--TPAPEDNGCP 608 G G G PG PG GP GPPGPPG G P E P + G P Sbjct: 195 GSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLP 245 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 169 bits (428), Expect = 9e-42 Identities = 86/179 (48%), Positives = 100/179 (55%), Gaps = 24/179 (13%) Query: 443 GPPGPRGPRGDRGSQGPPGPTG---------------------NKGQKGEKGEPGPPGPA 481 GPPG +GP GD G +G PGP G +KG+ G+ G+PGPPGP+ Sbjct: 1303 GPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPS 1362 Query: 482 GERGPIGPAG---PPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLP 538 GE GP GP G PPG G +G +G +G KG G+ G PG GP G GP G PG EGL Sbjct: 1363 GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR 1422 Query: 539 GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNE 597 G GP G QGL G G+ G PGP G PGLPG+ G PG KG G PG G + P Q E Sbjct: 1423 GIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE 1481 Score = 166 bits (421), Expect = 6e-41 Identities = 91/203 (44%), Positives = 101/203 (49%), Gaps = 45/203 (22%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP---------- 492 GP G RGP G RGS+G GPTG G KG G GPPGP GERGP GP GP Sbjct: 889 GPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPP 948 Query: 493 --------PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD---------PGPPGPPGKE 535 PG G +G G QG G G G GPQGP+G+ PGPPGPPG++ Sbjct: 949 GPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQ 1008 Query: 536 GLPGPQG---------PPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGP- 585 GLPG G P G G G G G PG RGLPG G PG+ G +GP GPPGP Sbjct: 1009 GLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV 1068 Query: 586 --------SGAVVPLALQNEPTP 600 +G P+ L P P Sbjct: 1069 GSPGERGSAGTAGPIGLPGRPGP 1091 Score = 164 bits (414), Expect = 4e-40 Identities = 85/177 (48%), Positives = 101/177 (57%), Gaps = 11/177 (6%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE---PGPPGPAGERGPIGPAGPPGERGGK 499 G PGP G G++G G PG G G++G KG PG PG GE+G G AG PG RG + Sbjct: 835 GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 894 Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV- 558 G G +G +G+RG GKPGP+G SG GPPGPPG+ G GPQGP GF G +G G PG Sbjct: 895 GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 954 Query: 559 -----PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP--APEDNGCP 608 PG RG G G G PGP G GP GP+G P+ + P P P + G P Sbjct: 955 GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLP 1011 Score = 163 bits (412), Expect = 6e-40 Identities = 92/183 (50%), Positives = 97/183 (53%), Gaps = 33/183 (18%) Query: 442 QGPPGPRGPRGDRGS---------------QGPPGPTGNKGQKGEKGEPGP------PGP 480 QGPPGP G G+RGS QGPPGP G KG GEKG GP GP Sbjct: 1062 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1121 Query: 481 AGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP 540 G GP GPAG PGE G KG G G KGS+G G+ GP GP G GP G PG G G Sbjct: 1122 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGE 1181 Query: 541 QGPPGFQGL------QGTVGEPGVPGPRGLPGLPGVPGMP------GPKGPPGPPGPSGA 588 GP G QG+ +G G PG PGP GL GLPG PG GP GPPGPPGP G Sbjct: 1182 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGP 1241 Query: 589 VVP 591 P Sbjct: 1242 QGP 1244 Score = 162 bits (410), Expect = 1e-39 Identities = 84/164 (51%), Positives = 94/164 (57%), Gaps = 12/164 (7%) Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGP 492 + F L G PG +G RG+RG QGPPGP G+ G +GE GE GP PG AG RG +GP G Sbjct: 612 RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGT 671 Query: 493 PGE---------RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGP 543 PG G G KG+ GP+G G PG+ G GP G PGP GP G G GPQG Sbjct: 672 PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 731 Query: 544 PGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 PG GL G G PG PG G G G G PGP+GP G PGP G Sbjct: 732 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRG 775 Score = 162 bits (410), Expect = 1e-39 Identities = 90/197 (45%), Positives = 100/197 (50%), Gaps = 36/197 (18%) Query: 443 GPPGPRGPRGDRGSQGPPGP---------TGNKGQKGEKGEPGPP------GPAGERGPI 487 GPPGPRGP+G G+ GP GP G KG+ GE G PGPP GP GERG Sbjct: 1234 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1293 Query: 488 GPAGPPGER---GGKGSKGSQGPKGS---------RGSPGKPGP---------QGPSGDP 526 G AGPPG G KG G GPKG+ G PG+PGP +G GDP Sbjct: 1294 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDP 1353 Query: 527 GPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPS 586 G PGPPG G GP GPPG +G G G G G +G G G G PG GP GP GP+ Sbjct: 1354 GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPA 1413 Query: 587 GAVVPLALQNEPTPAPE 603 G P L+ P P E Sbjct: 1414 GKPGPEGLRGIPGPVGE 1430 Score = 160 bits (406), Expect = 3e-39 Identities = 86/173 (49%), Positives = 95/173 (54%), Gaps = 11/173 (6%) Query: 443 GPPGPRG---PRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---PAGPPGER 496 GPPG G P+G+RG +G GP G G G KG PG GP G GP+G GPPGE Sbjct: 1276 GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEP 1335 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G G G G KG G PG+PGP GPSG+ GPPGPPGK G PG G G QG +G GE Sbjct: 1336 GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEA 1395 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609 G GP PG G G GP G PGP G G P+ Q P A +D PP Sbjct: 1396 GAEGP---PGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDG--PP 1443 Score = 159 bits (403), Expect = 7e-39 Identities = 82/170 (48%), Positives = 98/170 (57%), Gaps = 7/170 (4%) Query: 443 GPPGPRG---PRGDRGSQGPPGPTG---NKGQKGEKGEPGPPGPAGERGPIGPAGPPGER 496 GPPGP G P G G +GPPG G +G+KG KGE G GP G+ GP+GP GP G+ Sbjct: 1357 GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1416 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G +G +G GP G +G PG G GP G GPPG PG +G PG +G G GL G +G P Sbjct: 1417 GPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPP 1476 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP-APEDN 605 G G +G GLPG G PG KG G PGP+G + P P P P+ N Sbjct: 1477 GEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN 1526 Score = 158 bits (400), Expect = 2e-38 Identities = 85/175 (48%), Positives = 96/175 (54%), Gaps = 18/175 (10%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERG--- 497 L+GPPGP G G GP G G+ G KGE G+PGP GP G +GP GP G PG+RG Sbjct: 539 LRGPPGPMGLTG---RPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPG 595 Query: 498 ---GKGSKGSQGPKGSRGS------PGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG 548 G+G G G KG RG PG G +G G GPPGPPG +G+ G G G +G Sbjct: 596 ADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRG 655 Query: 549 LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPP---GPSGAVVPLALQNEPTP 600 L G G G+ GPRG PG PG PGM G GPPGP GP G P Q P P Sbjct: 656 LPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 710 Score = 158 bits (399), Expect = 2e-38 Identities = 81/158 (51%), Positives = 95/158 (60%), Gaps = 15/158 (9%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG------ERGPIGPAGPPGE 495 +G PG G +GDRG G PG G+KG +GE+G GPPGP G E G IGP G PGE Sbjct: 600 RGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGE 659 Query: 496 RGGKGSKGSQGPKGSRGSPGK------PGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGL 549 G +G G +G G+ G PG PGP+G G G PGPPG++G PGPQG P G Sbjct: 660 AGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLP---GP 716 Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 QG +G PG GP+G PGL G+PG GP G PG G SG Sbjct: 717 QGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSG 754 Score = 157 bits (398), Expect = 3e-38 Identities = 78/153 (50%), Positives = 89/153 (58%), Gaps = 6/153 (3%) Query: 441 LQGPPGPRGPRGDR------GSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG 494 +QGPPGP G G R G +G PG G KG +G G PG PG G RG GP GPPG Sbjct: 578 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 637 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVG 554 G G +G G G RG PG+ GP+G G G PG PG+ G+ G GPPG +G G G Sbjct: 638 PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG 697 Query: 555 EPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 EPG PG +G PG G+PG GP GPPG GP G Sbjct: 698 EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQG 730 Score = 156 bits (395), Expect = 6e-38 Identities = 86/187 (45%), Positives = 96/187 (51%), Gaps = 36/187 (19%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAG------PPG 494 L GP GP G G+ G +G G G KG KG+KGE GPPGP G +GP+G G PG Sbjct: 1124 LPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPG 1183 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGP---------------------QGPSGDPGPPGPPG 533 RG +G G +G +G+RG PG PGP GP G PGP GP G Sbjct: 1184 PRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQG 1243 Query: 534 KEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPK---------GPPGPPG 584 G GPQGPPG G G VGE G PG G PG PG G+ GPK GPPG G Sbjct: 1244 PNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAG 1303 Query: 585 PSGAVVP 591 P GA P Sbjct: 1304 PPGAKGP 1310 Score = 154 bits (390), Expect = 2e-37 Identities = 87/188 (46%), Positives = 95/188 (50%), Gaps = 30/188 (15%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPG---PAGERGPIGPAGPPGERG 497 L G PG +GP+G G G PG G KG +G G+PGP G P G RG G GP G+ G Sbjct: 854 LPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG 913 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGP---PGPPGKEGLP---------------- 538 KG+ G GP G G G GPQGP G PGP PGPPGK+GLP Sbjct: 914 PKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 973 Query: 539 --------GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVV 590 GPQGP G G G G PG PGP G GLPG G G KG PGP G SG Sbjct: 974 PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDG 1033 Query: 591 PLALQNEP 598 P L+ P Sbjct: 1034 PAGLRGFP 1041 Score = 154 bits (390), Expect = 2e-37 Identities = 80/172 (46%), Positives = 90/172 (52%), Gaps = 4/172 (2%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +G G GP G G QG PGP G KG+ G+ G GPPGP G RGP GP G G +G GS Sbjct: 1197 EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGS 1256 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGP 561 GS G G +G PG+ G GP G+ G GP G+ G G GPPG G G G PG GP Sbjct: 1257 VGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGP 1316 Query: 562 RGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP----TPAPEDNGCPP 609 +G PG G PG PGP G PGP G G +P P P PP Sbjct: 1317 KGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1368 Score = 153 bits (387), Expect = 5e-37 Identities = 80/162 (49%), Positives = 87/162 (53%), Gaps = 18/162 (11%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGP------------AGERGPIG 488 L GPPG +G GD G GPPGP G +G +G G GP GP GE G G Sbjct: 1214 LPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAG 1273 Query: 489 PAGPPGERGGKGSKGSQGPKGSRGSP---GKPGPQGPSGDPGPPGPPGKEGLPGPQGPPG 545 GPPGE G G KG +G KG G P G PG +GP GD GP G PG G PG GPP Sbjct: 1274 NPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP- 1332 Query: 546 FQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G G G+ GV G +G G PG PG PGP G GPPGP G Sbjct: 1333 --GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPG 1372 Score = 152 bits (385), Expect = 8e-37 Identities = 84/173 (48%), Positives = 90/173 (52%), Gaps = 16/173 (9%) Query: 448 RGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGP 507 RGP G G G PGP G G G KGE G PGP G RG GP GP G+ G +G G+ G Sbjct: 540 RGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGG 599 Query: 508 KGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLP-- 565 +G G PG G +G G PG PG G G GPQGPPG G G GE G GPRGLP Sbjct: 600 RGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGE 659 Query: 566 ----------GLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 G PG PG PG G GPPGP G + P Q EP P P G P Sbjct: 660 AGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGP---QGEPGP-PGQQGNP 708 Score = 152 bits (385), Expect = 8e-37 Identities = 86/186 (46%), Positives = 96/186 (51%), Gaps = 26/186 (13%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---PAGPPGERGG 498 +G PGP GP G +G GPPG G G G G PGPPGP G +GP G P GPPG G Sbjct: 1200 RGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGS 1259 Query: 499 KGSKGSQGPKGSRGSPGKPG------PQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552 G G +G G G+PG PG P+G G+ G GPPG G PG +GPPG G +G Sbjct: 1260 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1319 Query: 553 ---VGEPGVPGPRGLPGLPGVPGMPGPK------GPPGPPGPSGAVVPLALQNEPTPAPE 603 VG PG PGP G PG G G+ G K G PGPPGPSG P P P Sbjct: 1320 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGP--------PGPP 1371 Query: 604 DNGCPP 609 PP Sbjct: 1372 GKRGPP 1377 Score = 150 bits (379), Expect = 4e-36 Identities = 86/187 (45%), Positives = 97/187 (51%), Gaps = 36/187 (19%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKG------QKGEKGEPGPPGPAGERGPIGPAGPPGE 495 QGP G GP G+RG GPPGP G +G ++G KG+PGP G +G+ GP G G PGE Sbjct: 984 QGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGE 1043 Query: 496 RGG---------KGSKGSQGPKGSRGSPGK------------PGPQGPSGDPGPPGPPGK 534 RG KG +G QGP G GSPG+ PG GP G PGP G G Sbjct: 1044 RGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGA 1103 Query: 535 EGLPGPQGPPGFQGLQGTVGEPGVPGPRGLP---------GLPGVPGMPGPKGPPGPPGP 585 G GPQGP G G+QG VG PG GP G P G PG G G KG GPPGP Sbjct: 1104 PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGP 1163 Query: 586 SGAVVPL 592 G P+ Sbjct: 1164 PGLQGPV 1170 Score = 149 bits (376), Expect = 9e-36 Identities = 81/173 (46%), Positives = 93/173 (53%), Gaps = 5/173 (2%) Query: 439 TILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498 T QG GP GP G G QGP G TG G++G G PGPPG G G G G G+ G Sbjct: 966 TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 1025 Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT---VGE 555 +G G GP G RG PG+ G G G PG G G +G PGP G PG +G GT +G Sbjct: 1026 QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGL 1085 Query: 556 PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA--PEDNG 606 PG PGP+G PG G G PG KGP GP G G P+ L PA P ++G Sbjct: 1086 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG 1138 Score = 145 bits (365), Expect = 2e-34 Identities = 79/186 (42%), Positives = 98/186 (52%), Gaps = 22/186 (11%) Query: 443 GPPGPRGP---------------RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI 487 GPPG RGP +G+ G++GPPG TG G +G G+PGP G G GP+ Sbjct: 1369 GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV 1428 Query: 488 GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDP---GPPGPPGKEGLPGPQGPP 544 G G PG G G G GP G G G PG +G G P G GPPG++G G +G P Sbjct: 1429 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1488 Query: 545 GFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP-TPAPE 603 G QG G G+ G+PGP G G PG PG+PGP+GP G G +G P + + P P Sbjct: 1489 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTG---PAGQKGDSGLPGPP 1545 Query: 604 DNGCPP 609 + PP Sbjct: 1546 GSPGPP 1551 Score = 144 bits (364), Expect = 2e-34 Identities = 84/196 (42%), Positives = 92/196 (46%), Gaps = 51/196 (26%) Query: 443 GPPGPRGP------RGDRGSQGPPGPTGNKGQKGE------------------------K 472 GPPGP+GP RG +G+ G G G+KG+KGE + Sbjct: 760 GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 819 Query: 473 GEPGPPGPAGERGPIGPAGPPGERGGKGS---------KGSQGPKGSRGSPGKPGPQ--- 520 GE GP GP G GP G GP G+ G KG G QGPKGS G PG PG Sbjct: 820 GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 879 Query: 521 ---------GPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVP 571 GP G GP GP G G GP G PG +G G G PG PG RG G G Sbjct: 880 GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPV 939 Query: 572 GMPGPKGPPGPPGPSG 587 G PGPKGPPGPPG G Sbjct: 940 GFPGPKGPPGPPGKDG 955 Score = 144 bits (364), Expect = 2e-34 Identities = 73/145 (50%), Positives = 86/145 (59%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GP G RG G+RG G G G KG +G +G PGP G GERG G AGP G G G + Sbjct: 1033 GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQ 1092 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G GP G +G+PG+ GPQGP+G G GP G G GP G PG G +G +GEPG G + Sbjct: 1093 GPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSK 1152 Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSG 587 G G G PG PG +GP G PG +G Sbjct: 1153 GDKGENGPPGPPGLQGPVGAPGIAG 1177 Score = 144 bits (363), Expect = 3e-34 Identities = 79/165 (47%), Positives = 91/165 (55%), Gaps = 15/165 (9%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGPPGERGG 498 +G PG G G G GPPGP GN G +GE G PG PGP G GP GP GPPGE+G Sbjct: 669 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 728 Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDP---GPPGPPGKEGLPGP---QGPPGFQGLQGT 552 +G G G G+ G PG PG +G SG+ GPPGP G G PGP +G G +GL+G+ Sbjct: 729 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 788 Query: 553 VGE------PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 GE PG G GL G G G GP+G GP GP G P Sbjct: 789 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP 833 Score = 144 bits (363), Expect = 3e-34 Identities = 84/203 (41%), Positives = 98/203 (48%), Gaps = 36/203 (17%) Query: 443 GPPGPRGPRGDRG------SQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGER 496 GPPG +GP+G G + GPPG G +GQ GEKG GPPGP G G GP G G Sbjct: 721 GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGAD 780 Query: 497 GGKGSKGSQGPKGSRGSPG---------------------KPGPQGPSGDPGPPGPPG-- 533 G +G KGS+G KG G PG + GP+GP G GP G PG Sbjct: 781 GVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPS 840 Query: 534 -------KEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPS 586 K G+PG G PG QG +G+ G PG PG G G GV G PGP+G GP GP Sbjct: 841 GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPR 900 Query: 587 GAVVPLALQNEPTPAPEDNGCPP 609 G+ +P P G P Sbjct: 901 GSRGARGPTGKPGPKGTSGGDGP 923 Score = 144 bits (362), Expect = 4e-34 Identities = 84/189 (44%), Positives = 97/189 (51%), Gaps = 32/189 (16%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 L G G G +G G QGPPGP G+ G++G G GP G G GP GP GP GE+G G Sbjct: 1046 LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1105 Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP---PGKEGLPGPQGPPGFQGLQGTVGEPG 557 KG QGP G + G QGP G PGP GP PG++G G G PG +G +G GE G Sbjct: 1106 EKGPQGPAG------RDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1159 Query: 558 VPGPRGLPGLPGVPGMPGPKGPPGP------------------PGPSGAVVPLALQNEPT 599 PGP GL G G PG+ G G PGP PGP G P+ LQ P Sbjct: 1160 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG---PIGLQGLPG 1216 Query: 600 PAPE--DNG 606 P E +NG Sbjct: 1217 PPGEKGENG 1225 Score = 142 bits (359), Expect = 9e-34 Identities = 83/193 (43%), Positives = 96/193 (49%), Gaps = 45/193 (23%) Query: 440 ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP----PGE 495 +++GPPGP GP G G G GPTG G G++G PG PG G G GP G P Sbjct: 451 LVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFR 510 Query: 496 RGGKGSKGS--------------------QGPKGSRGSPGKPGP---------QGPSGDP 526 GG GSKG +GP G G G+PGP +G SGDP Sbjct: 511 YGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDP 570 Query: 527 GPPGPPGKEGLPGPQGPPGFQGL------QGTVGEPGVPGPRGLPGLPGVP------GMP 574 GP GP G +G PGP G PG +G +G GEPG G RG GLPG+P G Sbjct: 571 GPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER 630 Query: 575 GPKGPPGPPGPSG 587 GP+GPPGPPG G Sbjct: 631 GPQGPPGPPGDDG 643 Score = 142 bits (359), Expect = 9e-34 Identities = 77/158 (48%), Positives = 88/158 (55%), Gaps = 9/158 (5%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +GPPG GP G +G G PGP G +G G GE G PG AG+ GP GP GPPG G KG Sbjct: 1398 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD 1457 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGP---PGFQGLQGTVGEPGV 558 GS+G KG G G GP G G+ G G PG +G PG +G PG G G G PG+ Sbjct: 1458 PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL 1517 Query: 559 PGPRGLPGLPGVPGMPGPK------GPPGPPGPSGAVV 590 PGP+G G G G G K GPPG PGP G V+ Sbjct: 1518 PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVI 1555 Score = 142 bits (358), Expect = 1e-33 Identities = 81/172 (47%), Positives = 89/172 (51%), Gaps = 12/172 (6%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 LQGP G G G G GP G G GQKG++G G PGP G G G GPPGE+ G Sbjct: 1166 LQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK---G 1222 Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL---PGPQGPPGFQGLQGTVGEPG 557 G GP G G PG GPQGP+G GP GPPG G G +G PG G G GE G Sbjct: 1223 ENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1282 Query: 558 VPGP------RGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPE 603 V GP +G G PG G PG KGPPG GP G P+ +P P E Sbjct: 1283 VGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1334 Score = 141 bits (355), Expect = 2e-33 Identities = 78/173 (45%), Positives = 93/173 (53%), Gaps = 15/173 (8%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGP---AGPPGERG 497 + GPPGP+G G +G GPPG GN G +G G GP GP GE+GP G AG PG G Sbjct: 683 VDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADG 742 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGP---------PGFQ- 547 G G +G G +G+ G PGPQGP G PGP G G +G+ G +G PGF+ Sbjct: 743 PPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKG 802 Query: 548 --GLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598 GL+G GE G GPRG G G G GP G PGP G +G L + P Sbjct: 803 DMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLP 855 Score = 136 bits (343), Expect = 6e-32 Identities = 72/142 (50%), Positives = 83/142 (58%), Gaps = 6/142 (4%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 + GP G +G G G GPPGP G G G KG+PG G G G IG GPPGE+G KG Sbjct: 1424 IPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKG 1483 Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPG 560 +G G +GS G+ G G GP+G GPPGPP GLPGPQGP +G +G+ G G G Sbjct: 1484 DRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP---GLPGPQGP---KGNKGSTGPAGQKG 1537 Query: 561 PRGLPGLPGVPGMPGPKGPPGP 582 GLPG PG PG PG P P Sbjct: 1538 DSGLPGPPGSPGPPGEVIQPLP 1559 Score = 99.8 bits (247), Expect = 8e-21 Identities = 76/199 (38%), Positives = 86/199 (43%), Gaps = 46/199 (23%) Query: 447 PRGPRGDRGSQGPPGPT----------GNKGQKGEKGEP----------GPPGPAGERGP 486 P P + G P T G G+KG+KGEP GPPGPAG P Sbjct: 405 PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAG---P 461 Query: 487 IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP----PGKEGLPGPQG 542 G GPPG +G G G G RG PG+PG G G PGPPG P + G G +G Sbjct: 462 AGIMGPPGLQGPTGPPGDPG---DRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKG 518 Query: 543 PP------GFQGL--QGTVGEPGVPGPRGLPGLPGV---PGMPGPKGPPGPPGPSGAVVP 591 P Q + Q + G PGP GL G PG PG G KG G PGP G P Sbjct: 519 PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQG---P 575 Query: 592 LALQNEPTPA--PEDNGCP 608 +Q P P P G P Sbjct: 576 RGVQGPPGPTGKPGKRGRP 594 Score = 53.9 bits (128), Expect = 5e-07 Identities = 23/45 (51%), Positives = 29/45 (64%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI 487 G PGP+GP+G++GS GP G G+ G G G PGPPG + PI Sbjct: 1516 GLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPI 1560 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 169 bits (428), Expect = 9e-42 Identities = 86/179 (48%), Positives = 100/179 (55%), Gaps = 24/179 (13%) Query: 443 GPPGPRGPRGDRGSQGPPGPTG---------------------NKGQKGEKGEPGPPGPA 481 GPPG +GP GD G +G PGP G +KG+ G+ G+PGPPGP+ Sbjct: 1252 GPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPS 1311 Query: 482 GERGPIGPAG---PPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLP 538 GE GP GP G PPG G +G +G +G KG G+ G PG GP G GP G PG EGL Sbjct: 1312 GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR 1371 Query: 539 GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNE 597 G GP G QGL G G+ G PGP G PGLPG+ G PG KG G PG G + P Q E Sbjct: 1372 GIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE 1430 Score = 166 bits (421), Expect = 6e-41 Identities = 91/203 (44%), Positives = 101/203 (49%), Gaps = 45/203 (22%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP---------- 492 GP G RGP G RGS+G GPTG G KG G GPPGP GERGP GP GP Sbjct: 838 GPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPP 897 Query: 493 --------PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD---------PGPPGPPGKE 535 PG G +G G QG G G G GPQGP+G+ PGPPGPPG++ Sbjct: 898 GPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQ 957 Query: 536 GLPGPQG---------PPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGP- 585 GLPG G P G G G G G PG RGLPG G PG+ G +GP GPPGP Sbjct: 958 GLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV 1017 Query: 586 --------SGAVVPLALQNEPTP 600 +G P+ L P P Sbjct: 1018 GSPGERGSAGTAGPIGLPGRPGP 1040 Score = 164 bits (414), Expect = 4e-40 Identities = 85/177 (48%), Positives = 101/177 (57%), Gaps = 11/177 (6%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE---PGPPGPAGERGPIGPAGPPGERGGK 499 G PGP G G++G G PG G G++G KG PG PG GE+G G AG PG RG + Sbjct: 784 GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 843 Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV- 558 G G +G +G+RG GKPGP+G SG GPPGPPG+ G GPQGP GF G +G G PG Sbjct: 844 GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 903 Query: 559 -----PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP--APEDNGCP 608 PG RG G G G PGP G GP GP+G P+ + P P P + G P Sbjct: 904 GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLP 960 Score = 163 bits (412), Expect = 6e-40 Identities = 92/183 (50%), Positives = 97/183 (53%), Gaps = 33/183 (18%) Query: 442 QGPPGPRGPRGDRGS---------------QGPPGPTGNKGQKGEKGEPGP------PGP 480 QGPPGP G G+RGS QGPPGP G KG GEKG GP GP Sbjct: 1011 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1070 Query: 481 AGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP 540 G GP GPAG PGE G KG G G KGS+G G+ GP GP G GP G PG G G Sbjct: 1071 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGE 1130 Query: 541 QGPPGFQGL------QGTVGEPGVPGPRGLPGLPGVPGMP------GPKGPPGPPGPSGA 588 GP G QG+ +G G PG PGP GL GLPG PG GP GPPGPPGP G Sbjct: 1131 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGP 1190 Query: 589 VVP 591 P Sbjct: 1191 QGP 1193 Score = 162 bits (410), Expect = 1e-39 Identities = 84/164 (51%), Positives = 94/164 (57%), Gaps = 12/164 (7%) Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGP 492 + F L G PG +G RG+RG QGPPGP G+ G +GE GE GP PG AG RG +GP G Sbjct: 561 RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGT 620 Query: 493 PGE---------RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGP 543 PG G G KG+ GP+G G PG+ G GP G PGP GP G G GPQG Sbjct: 621 PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 680 Query: 544 PGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 PG GL G G PG PG G G G G PGP+GP G PGP G Sbjct: 681 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRG 724 Score = 162 bits (410), Expect = 1e-39 Identities = 90/197 (45%), Positives = 100/197 (50%), Gaps = 36/197 (18%) Query: 443 GPPGPRGPRGDRGSQGPPGP---------TGNKGQKGEKGEPGPP------GPAGERGPI 487 GPPGPRGP+G G+ GP GP G KG+ GE G PGPP GP GERG Sbjct: 1183 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1242 Query: 488 GPAGPPGER---GGKGSKGSQGPKGS---------RGSPGKPGP---------QGPSGDP 526 G AGPPG G KG G GPKG+ G PG+PGP +G GDP Sbjct: 1243 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDP 1302 Query: 527 GPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPS 586 G PGPPG G GP GPPG +G G G G G +G G G G PG GP GP GP+ Sbjct: 1303 GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPA 1362 Query: 587 GAVVPLALQNEPTPAPE 603 G P L+ P P E Sbjct: 1363 GKPGPEGLRGIPGPVGE 1379 Score = 160 bits (406), Expect = 3e-39 Identities = 86/173 (49%), Positives = 95/173 (54%), Gaps = 11/173 (6%) Query: 443 GPPGPRG---PRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---PAGPPGER 496 GPPG G P+G+RG +G GP G G G KG PG GP G GP+G GPPGE Sbjct: 1225 GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEP 1284 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G G G G KG G PG+PGP GPSG+ GPPGPPGK G PG G G QG +G GE Sbjct: 1285 GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEA 1344 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609 G GP PG G G GP G PGP G G P+ Q P A +D PP Sbjct: 1345 GAEGP---PGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDG--PP 1392 Score = 159 bits (403), Expect = 7e-39 Identities = 82/170 (48%), Positives = 98/170 (57%), Gaps = 7/170 (4%) Query: 443 GPPGPRG---PRGDRGSQGPPGPTG---NKGQKGEKGEPGPPGPAGERGPIGPAGPPGER 496 GPPGP G P G G +GPPG G +G+KG KGE G GP G+ GP+GP GP G+ Sbjct: 1306 GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1365 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G +G +G GP G +G PG G GP G GPPG PG +G PG +G G GL G +G P Sbjct: 1366 GPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPP 1425 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP-APEDN 605 G G +G GLPG G PG KG G PGP+G + P P P P+ N Sbjct: 1426 GEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN 1475 Score = 158 bits (400), Expect = 2e-38 Identities = 85/175 (48%), Positives = 96/175 (54%), Gaps = 18/175 (10%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERG--- 497 L+GPPGP G G GP G G+ G KGE G+PGP GP G +GP GP G PG+RG Sbjct: 488 LRGPPGPMGLTG---RPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPG 544 Query: 498 ---GKGSKGSQGPKGSRGS------PGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG 548 G+G G G KG RG PG G +G G GPPGPPG +G+ G G G +G Sbjct: 545 ADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRG 604 Query: 549 LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPP---GPSGAVVPLALQNEPTP 600 L G G G+ GPRG PG PG PGM G GPPGP GP G P Q P P Sbjct: 605 LPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 659 Score = 158 bits (399), Expect = 2e-38 Identities = 81/158 (51%), Positives = 95/158 (60%), Gaps = 15/158 (9%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG------ERGPIGPAGPPGE 495 +G PG G +GDRG G PG G+KG +GE+G GPPGP G E G IGP G PGE Sbjct: 549 RGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGE 608 Query: 496 RGGKGSKGSQGPKGSRGSPGK------PGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGL 549 G +G G +G G+ G PG PGP+G G G PGPPG++G PGPQG P G Sbjct: 609 AGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLP---GP 665 Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 QG +G PG GP+G PGL G+PG GP G PG G SG Sbjct: 666 QGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSG 703 Score = 157 bits (398), Expect = 3e-38 Identities = 78/153 (50%), Positives = 89/153 (58%), Gaps = 6/153 (3%) Query: 441 LQGPPGPRGPRGDR------GSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG 494 +QGPPGP G G R G +G PG G KG +G G PG PG G RG GP GPPG Sbjct: 527 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 586 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVG 554 G G +G G G RG PG+ GP+G G G PG PG+ G+ G GPPG +G G G Sbjct: 587 PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG 646 Query: 555 EPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 EPG PG +G PG G+PG GP GPPG GP G Sbjct: 647 EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQG 679 Score = 156 bits (395), Expect = 6e-38 Identities = 86/187 (45%), Positives = 96/187 (51%), Gaps = 36/187 (19%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAG------PPG 494 L GP GP G G+ G +G G G KG KG+KGE GPPGP G +GP+G G PG Sbjct: 1073 LPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPG 1132 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGP---------------------QGPSGDPGPPGPPG 533 RG +G G +G +G+RG PG PGP GP G PGP GP G Sbjct: 1133 PRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQG 1192 Query: 534 KEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPK---------GPPGPPG 584 G GPQGPPG G G VGE G PG G PG PG G+ GPK GPPG G Sbjct: 1193 PNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAG 1252 Query: 585 PSGAVVP 591 P GA P Sbjct: 1253 PPGAKGP 1259 Score = 154 bits (390), Expect = 2e-37 Identities = 87/188 (46%), Positives = 95/188 (50%), Gaps = 30/188 (15%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPG---PAGERGPIGPAGPPGERG 497 L G PG +GP+G G G PG G KG +G G+PGP G P G RG G GP G+ G Sbjct: 803 LPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG 862 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGP---PGPPGKEGLP---------------- 538 KG+ G GP G G G GPQGP G PGP PGPPGK+GLP Sbjct: 863 PKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 922 Query: 539 --------GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVV 590 GPQGP G G G G PG PGP G GLPG G G KG PGP G SG Sbjct: 923 PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDG 982 Query: 591 PLALQNEP 598 P L+ P Sbjct: 983 PAGLRGFP 990 Score = 154 bits (390), Expect = 2e-37 Identities = 80/172 (46%), Positives = 90/172 (52%), Gaps = 4/172 (2%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +G G GP G G QG PGP G KG+ G+ G GPPGP G RGP GP G G +G GS Sbjct: 1146 EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGS 1205 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGP 561 GS G G +G PG+ G GP G+ G GP G+ G G GPPG G G G PG GP Sbjct: 1206 VGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGP 1265 Query: 562 RGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP----TPAPEDNGCPP 609 +G PG G PG PGP G PGP G G +P P P PP Sbjct: 1266 KGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1317 Score = 153 bits (387), Expect = 5e-37 Identities = 80/162 (49%), Positives = 87/162 (53%), Gaps = 18/162 (11%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGP------------AGERGPIG 488 L GPPG +G GD G GPPGP G +G +G G GP GP GE G G Sbjct: 1163 LPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAG 1222 Query: 489 PAGPPGERGGKGSKGSQGPKGSRGSP---GKPGPQGPSGDPGPPGPPGKEGLPGPQGPPG 545 GPPGE G G KG +G KG G P G PG +GP GD GP G PG G PG GPP Sbjct: 1223 NPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP- 1281 Query: 546 FQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G G G+ GV G +G G PG PG PGP G GPPGP G Sbjct: 1282 --GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPG 1321 Score = 152 bits (385), Expect = 8e-37 Identities = 84/173 (48%), Positives = 90/173 (52%), Gaps = 16/173 (9%) Query: 448 RGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGP 507 RGP G G G PGP G G G KGE G PGP G RG GP GP G+ G +G G+ G Sbjct: 489 RGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGG 548 Query: 508 KGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLP-- 565 +G G PG G +G G PG PG G G GPQGPPG G G GE G GPRGLP Sbjct: 549 RGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGE 608 Query: 566 ----------GLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 G PG PG PG G GPPGP G + P Q EP P P G P Sbjct: 609 AGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGP---QGEPGP-PGQQGNP 657 Score = 152 bits (385), Expect = 8e-37 Identities = 86/186 (46%), Positives = 96/186 (51%), Gaps = 26/186 (13%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---PAGPPGERGG 498 +G PGP GP G +G GPPG G G G G PGPPGP G +GP G P GPPG G Sbjct: 1149 RGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGS 1208 Query: 499 KGSKGSQGPKGSRGSPGKPG------PQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552 G G +G G G+PG PG P+G G+ G GPPG G PG +GPPG G +G Sbjct: 1209 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1268 Query: 553 ---VGEPGVPGPRGLPGLPGVPGMPGPK------GPPGPPGPSGAVVPLALQNEPTPAPE 603 VG PG PGP G PG G G+ G K G PGPPGPSG P P P Sbjct: 1269 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGP--------PGPP 1320 Query: 604 DNGCPP 609 PP Sbjct: 1321 GKRGPP 1326 Score = 150 bits (379), Expect = 4e-36 Identities = 86/187 (45%), Positives = 97/187 (51%), Gaps = 36/187 (19%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKG------QKGEKGEPGPPGPAGERGPIGPAGPPGE 495 QGP G GP G+RG GPPGP G +G ++G KG+PGP G +G+ GP G G PGE Sbjct: 933 QGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGE 992 Query: 496 RGG---------KGSKGSQGPKGSRGSPGK------------PGPQGPSGDPGPPGPPGK 534 RG KG +G QGP G GSPG+ PG GP G PGP G G Sbjct: 993 RGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGA 1052 Query: 535 EGLPGPQGPPGFQGLQGTVGEPGVPGPRGLP---------GLPGVPGMPGPKGPPGPPGP 585 G GPQGP G G+QG VG PG GP G P G PG G G KG GPPGP Sbjct: 1053 PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGP 1112 Query: 586 SGAVVPL 592 G P+ Sbjct: 1113 PGLQGPV 1119 Score = 149 bits (376), Expect = 9e-36 Identities = 81/173 (46%), Positives = 93/173 (53%), Gaps = 5/173 (2%) Query: 439 TILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498 T QG GP GP G G QGP G TG G++G G PGPPG G G G G G+ G Sbjct: 915 TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 974 Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT---VGE 555 +G G GP G RG PG+ G G G PG G G +G PGP G PG +G GT +G Sbjct: 975 QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGL 1034 Query: 556 PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA--PEDNG 606 PG PGP+G PG G G PG KGP GP G G P+ L PA P ++G Sbjct: 1035 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG 1087 Score = 145 bits (365), Expect = 2e-34 Identities = 79/186 (42%), Positives = 98/186 (52%), Gaps = 22/186 (11%) Query: 443 GPPGPRGP---------------RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI 487 GPPG RGP +G+ G++GPPG TG G +G G+PGP G G GP+ Sbjct: 1318 GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV 1377 Query: 488 GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDP---GPPGPPGKEGLPGPQGPP 544 G G PG G G G GP G G G PG +G G P G GPPG++G G +G P Sbjct: 1378 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1437 Query: 545 GFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP-TPAPE 603 G QG G G+ G+PGP G G PG PG+PGP+GP G G +G P + + P P Sbjct: 1438 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTG---PAGQKGDSGLPGPP 1494 Query: 604 DNGCPP 609 + PP Sbjct: 1495 GSPGPP 1500 Score = 144 bits (364), Expect = 2e-34 Identities = 84/196 (42%), Positives = 92/196 (46%), Gaps = 51/196 (26%) Query: 443 GPPGPRGP------RGDRGSQGPPGPTGNKGQKGE------------------------K 472 GPPGP+GP RG +G+ G G G+KG+KGE + Sbjct: 709 GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 768 Query: 473 GEPGPPGPAGERGPIGPAGPPGERGGKGS---------KGSQGPKGSRGSPGKPGPQ--- 520 GE GP GP G GP G GP G+ G KG G QGPKGS G PG PG Sbjct: 769 GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 828 Query: 521 ---------GPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVP 571 GP G GP GP G G GP G PG +G G G PG PG RG G G Sbjct: 829 GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPV 888 Query: 572 GMPGPKGPPGPPGPSG 587 G PGPKGPPGPPG G Sbjct: 889 GFPGPKGPPGPPGKDG 904 Score = 144 bits (364), Expect = 2e-34 Identities = 73/145 (50%), Positives = 86/145 (59%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GP G RG G+RG G G G KG +G +G PGP G GERG G AGP G G G + Sbjct: 982 GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQ 1041 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G GP G +G+PG+ GPQGP+G G GP G G GP G PG G +G +GEPG G + Sbjct: 1042 GPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSK 1101 Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSG 587 G G G PG PG +GP G PG +G Sbjct: 1102 GDKGENGPPGPPGLQGPVGAPGIAG 1126 Score = 144 bits (363), Expect = 3e-34 Identities = 79/165 (47%), Positives = 91/165 (55%), Gaps = 15/165 (9%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGPPGERGG 498 +G PG G G G GPPGP GN G +GE G PG PGP G GP GP GPPGE+G Sbjct: 618 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 677 Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDP---GPPGPPGKEGLPGP---QGPPGFQGLQGT 552 +G G G G+ G PG PG +G SG+ GPPGP G G PGP +G G +GL+G+ Sbjct: 678 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 737 Query: 553 VGE------PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 GE PG G GL G G G GP+G GP GP G P Sbjct: 738 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP 782 Score = 144 bits (363), Expect = 3e-34 Identities = 84/203 (41%), Positives = 98/203 (48%), Gaps = 36/203 (17%) Query: 443 GPPGPRGPRGDRG------SQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGER 496 GPPG +GP+G G + GPPG G +GQ GEKG GPPGP G G GP G G Sbjct: 670 GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGAD 729 Query: 497 GGKGSKGSQGPKGSRGSPG---------------------KPGPQGPSGDPGPPGPPG-- 533 G +G KGS+G KG G PG + GP+GP G GP G PG Sbjct: 730 GVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPS 789 Query: 534 -------KEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPS 586 K G+PG G PG QG +G+ G PG PG G G GV G PGP+G GP GP Sbjct: 790 GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPR 849 Query: 587 GAVVPLALQNEPTPAPEDNGCPP 609 G+ +P P G P Sbjct: 850 GSRGARGPTGKPGPKGTSGGDGP 872 Score = 144 bits (362), Expect = 4e-34 Identities = 84/189 (44%), Positives = 97/189 (51%), Gaps = 32/189 (16%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 L G G G +G G QGPPGP G+ G++G G GP G G GP GP GP GE+G G Sbjct: 995 LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1054 Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP---PGKEGLPGPQGPPGFQGLQGTVGEPG 557 KG QGP G + G QGP G PGP GP PG++G G G PG +G +G GE G Sbjct: 1055 EKGPQGPAG------RDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1108 Query: 558 VPGPRGLPGLPGVPGMPGPKGPPGP------------------PGPSGAVVPLALQNEPT 599 PGP GL G G PG+ G G PGP PGP G P+ LQ P Sbjct: 1109 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG---PIGLQGLPG 1165 Query: 600 PAPE--DNG 606 P E +NG Sbjct: 1166 PPGEKGENG 1174 Score = 142 bits (359), Expect = 9e-34 Identities = 83/193 (43%), Positives = 96/193 (49%), Gaps = 45/193 (23%) Query: 440 ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP----PGE 495 +++GPPGP GP G G G GPTG G G++G PG PG G G GP G P Sbjct: 400 LVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFR 459 Query: 496 RGGKGSKGS--------------------QGPKGSRGSPGKPGP---------QGPSGDP 526 GG GSKG +GP G G G+PGP +G SGDP Sbjct: 460 YGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDP 519 Query: 527 GPPGPPGKEGLPGPQGPPGFQGL------QGTVGEPGVPGPRGLPGLPGVP------GMP 574 GP GP G +G PGP G PG +G +G GEPG G RG GLPG+P G Sbjct: 520 GPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER 579 Query: 575 GPKGPPGPPGPSG 587 GP+GPPGPPG G Sbjct: 580 GPQGPPGPPGDDG 592 Score = 142 bits (359), Expect = 9e-34 Identities = 77/158 (48%), Positives = 88/158 (55%), Gaps = 9/158 (5%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +GPPG GP G +G G PGP G +G G GE G PG AG+ GP GP GPPG G KG Sbjct: 1347 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD 1406 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGP---PGFQGLQGTVGEPGV 558 GS+G KG G G GP G G+ G G PG +G PG +G PG G G G PG+ Sbjct: 1407 PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL 1466 Query: 559 PGPRGLPGLPGVPGMPGPK------GPPGPPGPSGAVV 590 PGP+G G G G G K GPPG PGP G V+ Sbjct: 1467 PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVI 1504 Score = 142 bits (358), Expect = 1e-33 Identities = 81/172 (47%), Positives = 89/172 (51%), Gaps = 12/172 (6%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 LQGP G G G G GP G G GQKG++G G PGP G G G GPPGE+ G Sbjct: 1115 LQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK---G 1171 Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL---PGPQGPPGFQGLQGTVGEPG 557 G GP G G PG GPQGP+G GP GPPG G G +G PG G G GE G Sbjct: 1172 ENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1231 Query: 558 VPGP------RGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPE 603 V GP +G G PG G PG KGPPG GP G P+ +P P E Sbjct: 1232 VGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1283 Score = 141 bits (355), Expect = 2e-33 Identities = 78/173 (45%), Positives = 93/173 (53%), Gaps = 15/173 (8%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGP---AGPPGERG 497 + GPPGP+G G +G GPPG GN G +G G GP GP GE+GP G AG PG G Sbjct: 632 VDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADG 691 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGP---------PGFQ- 547 G G +G G +G+ G PGPQGP G PGP G G +G+ G +G PGF+ Sbjct: 692 PPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKG 751 Query: 548 --GLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598 GL+G GE G GPRG G G G GP G PGP G +G L + P Sbjct: 752 DMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLP 804 Score = 136 bits (343), Expect = 6e-32 Identities = 72/142 (50%), Positives = 83/142 (58%), Gaps = 6/142 (4%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 + GP G +G G G GPPGP G G G KG+PG G G G IG GPPGE+G KG Sbjct: 1373 IPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKG 1432 Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPG 560 +G G +GS G+ G G GP+G GPPGPP GLPGPQGP +G +G+ G G G Sbjct: 1433 DRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP---GLPGPQGP---KGNKGSTGPAGQKG 1486 Query: 561 PRGLPGLPGVPGMPGPKGPPGP 582 GLPG PG PG PG P P Sbjct: 1487 DSGLPGPPGSPGPPGEVIQPLP 1508 Score = 99.8 bits (247), Expect = 8e-21 Identities = 76/199 (38%), Positives = 86/199 (43%), Gaps = 46/199 (23%) Query: 447 PRGPRGDRGSQGPPGPT----------GNKGQKGEKGEP----------GPPGPAGERGP 486 P P + G P T G G+KG+KGEP GPPGPAG P Sbjct: 354 PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAG---P 410 Query: 487 IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP----PGKEGLPGPQG 542 G GPPG +G G G G RG PG+PG G G PGPPG P + G G +G Sbjct: 411 AGIMGPPGLQGPTGPPGDPG---DRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKG 467 Query: 543 PP------GFQGL--QGTVGEPGVPGPRGLPGLPGV---PGMPGPKGPPGPPGPSGAVVP 591 P Q + Q + G PGP GL G PG PG G KG G PGP G P Sbjct: 468 PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQG---P 524 Query: 592 LALQNEPTPA--PEDNGCP 608 +Q P P P G P Sbjct: 525 RGVQGPPGPTGKPGKRGRP 543 Score = 53.9 bits (128), Expect = 5e-07 Identities = 23/45 (51%), Positives = 29/45 (64%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI 487 G PGP+GP+G++GS GP G G+ G G G PGPPG + PI Sbjct: 1465 GLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPI 1509 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 169 bits (428), Expect = 9e-42 Identities = 86/179 (48%), Positives = 100/179 (55%), Gaps = 24/179 (13%) Query: 443 GPPGPRGPRGDRGSQGPPGPTG---------------------NKGQKGEKGEPGPPGPA 481 GPPG +GP GD G +G PGP G +KG+ G+ G+PGPPGP+ Sbjct: 1291 GPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPS 1350 Query: 482 GERGPIGPAG---PPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLP 538 GE GP GP G PPG G +G +G +G KG G+ G PG GP G GP G PG EGL Sbjct: 1351 GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR 1410 Query: 539 GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNE 597 G GP G QGL G G+ G PGP G PGLPG+ G PG KG G PG G + P Q E Sbjct: 1411 GIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE 1469 Score = 166 bits (421), Expect = 6e-41 Identities = 91/203 (44%), Positives = 101/203 (49%), Gaps = 45/203 (22%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP---------- 492 GP G RGP G RGS+G GPTG G KG G GPPGP GERGP GP GP Sbjct: 877 GPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPP 936 Query: 493 --------PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD---------PGPPGPPGKE 535 PG G +G G QG G G G GPQGP+G+ PGPPGPPG++ Sbjct: 937 GPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQ 996 Query: 536 GLPGPQG---------PPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGP- 585 GLPG G P G G G G G PG RGLPG G PG+ G +GP GPPGP Sbjct: 997 GLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV 1056 Query: 586 --------SGAVVPLALQNEPTP 600 +G P+ L P P Sbjct: 1057 GSPGERGSAGTAGPIGLPGRPGP 1079 Score = 164 bits (414), Expect = 4e-40 Identities = 85/177 (48%), Positives = 101/177 (57%), Gaps = 11/177 (6%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE---PGPPGPAGERGPIGPAGPPGERGGK 499 G PGP G G++G G PG G G++G KG PG PG GE+G G AG PG RG + Sbjct: 823 GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 882 Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV- 558 G G +G +G+RG GKPGP+G SG GPPGPPG+ G GPQGP GF G +G G PG Sbjct: 883 GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 942 Query: 559 -----PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP--APEDNGCP 608 PG RG G G G PGP G GP GP+G P+ + P P P + G P Sbjct: 943 GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLP 999 Score = 163 bits (412), Expect = 6e-40 Identities = 92/183 (50%), Positives = 97/183 (53%), Gaps = 33/183 (18%) Query: 442 QGPPGPRGPRGDRGS---------------QGPPGPTGNKGQKGEKGEPGP------PGP 480 QGPPGP G G+RGS QGPPGP G KG GEKG GP GP Sbjct: 1050 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1109 Query: 481 AGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP 540 G GP GPAG PGE G KG G G KGS+G G+ GP GP G GP G PG G G Sbjct: 1110 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGE 1169 Query: 541 QGPPGFQGL------QGTVGEPGVPGPRGLPGLPGVPGMP------GPKGPPGPPGPSGA 588 GP G QG+ +G G PG PGP GL GLPG PG GP GPPGPPGP G Sbjct: 1170 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGP 1229 Query: 589 VVP 591 P Sbjct: 1230 QGP 1232 Score = 162 bits (410), Expect = 1e-39 Identities = 84/164 (51%), Positives = 94/164 (57%), Gaps = 12/164 (7%) Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGP 492 + F L G PG +G RG+RG QGPPGP G+ G +GE GE GP PG AG RG +GP G Sbjct: 600 RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGT 659 Query: 493 PGE---------RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGP 543 PG G G KG+ GP+G G PG+ G GP G PGP GP G G GPQG Sbjct: 660 PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 719 Query: 544 PGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 PG GL G G PG PG G G G G PGP+GP G PGP G Sbjct: 720 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRG 763 Score = 162 bits (410), Expect = 1e-39 Identities = 90/197 (45%), Positives = 100/197 (50%), Gaps = 36/197 (18%) Query: 443 GPPGPRGPRGDRGSQGPPGP---------TGNKGQKGEKGEPGPP------GPAGERGPI 487 GPPGPRGP+G G+ GP GP G KG+ GE G PGPP GP GERG Sbjct: 1222 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1281 Query: 488 GPAGPPGER---GGKGSKGSQGPKGS---------RGSPGKPGP---------QGPSGDP 526 G AGPPG G KG G GPKG+ G PG+PGP +G GDP Sbjct: 1282 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDP 1341 Query: 527 GPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPS 586 G PGPPG G GP GPPG +G G G G G +G G G G PG GP GP GP+ Sbjct: 1342 GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPA 1401 Query: 587 GAVVPLALQNEPTPAPE 603 G P L+ P P E Sbjct: 1402 GKPGPEGLRGIPGPVGE 1418 Score = 160 bits (406), Expect = 3e-39 Identities = 86/173 (49%), Positives = 95/173 (54%), Gaps = 11/173 (6%) Query: 443 GPPGPRG---PRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---PAGPPGER 496 GPPG G P+G+RG +G GP G G G KG PG GP G GP+G GPPGE Sbjct: 1264 GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEP 1323 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G G G G KG G PG+PGP GPSG+ GPPGPPGK G PG G G QG +G GE Sbjct: 1324 GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEA 1383 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609 G GP PG G G GP G PGP G G P+ Q P A +D PP Sbjct: 1384 GAEGP---PGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDG--PP 1431 Score = 159 bits (403), Expect = 7e-39 Identities = 82/170 (48%), Positives = 98/170 (57%), Gaps = 7/170 (4%) Query: 443 GPPGPRG---PRGDRGSQGPPGPTG---NKGQKGEKGEPGPPGPAGERGPIGPAGPPGER 496 GPPGP G P G G +GPPG G +G+KG KGE G GP G+ GP+GP GP G+ Sbjct: 1345 GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1404 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G +G +G GP G +G PG G GP G GPPG PG +G PG +G G GL G +G P Sbjct: 1405 GPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPP 1464 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP-APEDN 605 G G +G GLPG G PG KG G PGP+G + P P P P+ N Sbjct: 1465 GEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN 1514 Score = 158 bits (400), Expect = 2e-38 Identities = 85/175 (48%), Positives = 96/175 (54%), Gaps = 18/175 (10%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERG--- 497 L+GPPGP G G GP G G+ G KGE G+PGP GP G +GP GP G PG+RG Sbjct: 527 LRGPPGPMGLTG---RPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPG 583 Query: 498 ---GKGSKGSQGPKGSRGS------PGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG 548 G+G G G KG RG PG G +G G GPPGPPG +G+ G G G +G Sbjct: 584 ADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRG 643 Query: 549 LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPP---GPSGAVVPLALQNEPTP 600 L G G G+ GPRG PG PG PGM G GPPGP GP G P Q P P Sbjct: 644 LPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 698 Score = 158 bits (399), Expect = 2e-38 Identities = 81/158 (51%), Positives = 95/158 (60%), Gaps = 15/158 (9%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG------ERGPIGPAGPPGE 495 +G PG G +GDRG G PG G+KG +GE+G GPPGP G E G IGP G PGE Sbjct: 588 RGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGE 647 Query: 496 RGGKGSKGSQGPKGSRGSPGK------PGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGL 549 G +G G +G G+ G PG PGP+G G G PGPPG++G PGPQG P G Sbjct: 648 AGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLP---GP 704 Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 QG +G PG GP+G PGL G+PG GP G PG G SG Sbjct: 705 QGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSG 742 Score = 157 bits (398), Expect = 3e-38 Identities = 78/153 (50%), Positives = 89/153 (58%), Gaps = 6/153 (3%) Query: 441 LQGPPGPRGPRGDR------GSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG 494 +QGPPGP G G R G +G PG G KG +G G PG PG G RG GP GPPG Sbjct: 566 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 625 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVG 554 G G +G G G RG PG+ GP+G G G PG PG+ G+ G GPPG +G G G Sbjct: 626 PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG 685 Query: 555 EPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 EPG PG +G PG G+PG GP GPPG GP G Sbjct: 686 EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQG 718 Score = 156 bits (395), Expect = 6e-38 Identities = 86/187 (45%), Positives = 96/187 (51%), Gaps = 36/187 (19%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAG------PPG 494 L GP GP G G+ G +G G G KG KG+KGE GPPGP G +GP+G G PG Sbjct: 1112 LPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPG 1171 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGP---------------------QGPSGDPGPPGPPG 533 RG +G G +G +G+RG PG PGP GP G PGP GP G Sbjct: 1172 PRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQG 1231 Query: 534 KEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPK---------GPPGPPG 584 G GPQGPPG G G VGE G PG G PG PG G+ GPK GPPG G Sbjct: 1232 PNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAG 1291 Query: 585 PSGAVVP 591 P GA P Sbjct: 1292 PPGAKGP 1298 Score = 154 bits (390), Expect = 2e-37 Identities = 87/188 (46%), Positives = 95/188 (50%), Gaps = 30/188 (15%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPG---PAGERGPIGPAGPPGERG 497 L G PG +GP+G G G PG G KG +G G+PGP G P G RG G GP G+ G Sbjct: 842 LPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG 901 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGP---PGPPGKEGLP---------------- 538 KG+ G GP G G G GPQGP G PGP PGPPGK+GLP Sbjct: 902 PKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 961 Query: 539 --------GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVV 590 GPQGP G G G G PG PGP G GLPG G G KG PGP G SG Sbjct: 962 PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDG 1021 Query: 591 PLALQNEP 598 P L+ P Sbjct: 1022 PAGLRGFP 1029 Score = 154 bits (390), Expect = 2e-37 Identities = 80/172 (46%), Positives = 90/172 (52%), Gaps = 4/172 (2%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +G G GP G G QG PGP G KG+ G+ G GPPGP G RGP GP G G +G GS Sbjct: 1185 EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGS 1244 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGP 561 GS G G +G PG+ G GP G+ G GP G+ G G GPPG G G G PG GP Sbjct: 1245 VGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGP 1304 Query: 562 RGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP----TPAPEDNGCPP 609 +G PG G PG PGP G PGP G G +P P P PP Sbjct: 1305 KGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1356 Score = 153 bits (387), Expect = 5e-37 Identities = 80/162 (49%), Positives = 87/162 (53%), Gaps = 18/162 (11%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGP------------AGERGPIG 488 L GPPG +G GD G GPPGP G +G +G G GP GP GE G G Sbjct: 1202 LPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAG 1261 Query: 489 PAGPPGERGGKGSKGSQGPKGSRGSP---GKPGPQGPSGDPGPPGPPGKEGLPGPQGPPG 545 GPPGE G G KG +G KG G P G PG +GP GD GP G PG G PG GPP Sbjct: 1262 NPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP- 1320 Query: 546 FQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G G G+ GV G +G G PG PG PGP G GPPGP G Sbjct: 1321 --GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPG 1360 Score = 152 bits (385), Expect = 8e-37 Identities = 84/173 (48%), Positives = 90/173 (52%), Gaps = 16/173 (9%) Query: 448 RGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGP 507 RGP G G G PGP G G G KGE G PGP G RG GP GP G+ G +G G+ G Sbjct: 528 RGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGG 587 Query: 508 KGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLP-- 565 +G G PG G +G G PG PG G G GPQGPPG G G GE G GPRGLP Sbjct: 588 RGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGE 647 Query: 566 ----------GLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 G PG PG PG G GPPGP G + P Q EP P P G P Sbjct: 648 AGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGP---QGEPGP-PGQQGNP 696 Score = 152 bits (385), Expect = 8e-37 Identities = 86/186 (46%), Positives = 96/186 (51%), Gaps = 26/186 (13%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---PAGPPGERGG 498 +G PGP GP G +G GPPG G G G G PGPPGP G +GP G P GPPG G Sbjct: 1188 RGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGS 1247 Query: 499 KGSKGSQGPKGSRGSPGKPG------PQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552 G G +G G G+PG PG P+G G+ G GPPG G PG +GPPG G +G Sbjct: 1248 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1307 Query: 553 ---VGEPGVPGPRGLPGLPGVPGMPGPK------GPPGPPGPSGAVVPLALQNEPTPAPE 603 VG PG PGP G PG G G+ G K G PGPPGPSG P P P Sbjct: 1308 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGP--------PGPP 1359 Query: 604 DNGCPP 609 PP Sbjct: 1360 GKRGPP 1365 Score = 150 bits (379), Expect = 4e-36 Identities = 86/187 (45%), Positives = 97/187 (51%), Gaps = 36/187 (19%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKG------QKGEKGEPGPPGPAGERGPIGPAGPPGE 495 QGP G GP G+RG GPPGP G +G ++G KG+PGP G +G+ GP G G PGE Sbjct: 972 QGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGE 1031 Query: 496 RGG---------KGSKGSQGPKGSRGSPGK------------PGPQGPSGDPGPPGPPGK 534 RG KG +G QGP G GSPG+ PG GP G PGP G G Sbjct: 1032 RGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGA 1091 Query: 535 EGLPGPQGPPGFQGLQGTVGEPGVPGPRGLP---------GLPGVPGMPGPKGPPGPPGP 585 G GPQGP G G+QG VG PG GP G P G PG G G KG GPPGP Sbjct: 1092 PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGP 1151 Query: 586 SGAVVPL 592 G P+ Sbjct: 1152 PGLQGPV 1158 Score = 149 bits (376), Expect = 9e-36 Identities = 81/173 (46%), Positives = 93/173 (53%), Gaps = 5/173 (2%) Query: 439 TILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498 T QG GP GP G G QGP G TG G++G G PGPPG G G G G G+ G Sbjct: 954 TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 1013 Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT---VGE 555 +G G GP G RG PG+ G G G PG G G +G PGP G PG +G GT +G Sbjct: 1014 QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGL 1073 Query: 556 PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA--PEDNG 606 PG PGP+G PG G G PG KGP GP G G P+ L PA P ++G Sbjct: 1074 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG 1126 Score = 145 bits (365), Expect = 2e-34 Identities = 79/186 (42%), Positives = 98/186 (52%), Gaps = 22/186 (11%) Query: 443 GPPGPRGP---------------RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI 487 GPPG RGP +G+ G++GPPG TG G +G G+PGP G G GP+ Sbjct: 1357 GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV 1416 Query: 488 GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDP---GPPGPPGKEGLPGPQGPP 544 G G PG G G G GP G G G PG +G G P G GPPG++G G +G P Sbjct: 1417 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1476 Query: 545 GFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP-TPAPE 603 G QG G G+ G+PGP G G PG PG+PGP+GP G G +G P + + P P Sbjct: 1477 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTG---PAGQKGDSGLPGPP 1533 Query: 604 DNGCPP 609 + PP Sbjct: 1534 GSPGPP 1539 Score = 144 bits (364), Expect = 2e-34 Identities = 84/196 (42%), Positives = 92/196 (46%), Gaps = 51/196 (26%) Query: 443 GPPGPRGP------RGDRGSQGPPGPTGNKGQKGE------------------------K 472 GPPGP+GP RG +G+ G G G+KG+KGE + Sbjct: 748 GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 807 Query: 473 GEPGPPGPAGERGPIGPAGPPGERGGKGS---------KGSQGPKGSRGSPGKPGPQ--- 520 GE GP GP G GP G GP G+ G KG G QGPKGS G PG PG Sbjct: 808 GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 867 Query: 521 ---------GPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVP 571 GP G GP GP G G GP G PG +G G G PG PG RG G G Sbjct: 868 GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPV 927 Query: 572 GMPGPKGPPGPPGPSG 587 G PGPKGPPGPPG G Sbjct: 928 GFPGPKGPPGPPGKDG 943 Score = 144 bits (364), Expect = 2e-34 Identities = 73/145 (50%), Positives = 86/145 (59%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GP G RG G+RG G G G KG +G +G PGP G GERG G AGP G G G + Sbjct: 1021 GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQ 1080 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G GP G +G+PG+ GPQGP+G G GP G G GP G PG G +G +GEPG G + Sbjct: 1081 GPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSK 1140 Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSG 587 G G G PG PG +GP G PG +G Sbjct: 1141 GDKGENGPPGPPGLQGPVGAPGIAG 1165 Score = 144 bits (363), Expect = 3e-34 Identities = 79/165 (47%), Positives = 91/165 (55%), Gaps = 15/165 (9%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGPPGERGG 498 +G PG G G G GPPGP GN G +GE G PG PGP G GP GP GPPGE+G Sbjct: 657 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 716 Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDP---GPPGPPGKEGLPGP---QGPPGFQGLQGT 552 +G G G G+ G PG PG +G SG+ GPPGP G G PGP +G G +GL+G+ Sbjct: 717 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 776 Query: 553 VGE------PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 GE PG G GL G G G GP+G GP GP G P Sbjct: 777 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP 821 Score = 144 bits (363), Expect = 3e-34 Identities = 84/203 (41%), Positives = 98/203 (48%), Gaps = 36/203 (17%) Query: 443 GPPGPRGPRGDRG------SQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGER 496 GPPG +GP+G G + GPPG G +GQ GEKG GPPGP G G GP G G Sbjct: 709 GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGAD 768 Query: 497 GGKGSKGSQGPKGSRGSPG---------------------KPGPQGPSGDPGPPGPPG-- 533 G +G KGS+G KG G PG + GP+GP G GP G PG Sbjct: 769 GVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPS 828 Query: 534 -------KEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPS 586 K G+PG G PG QG +G+ G PG PG G G GV G PGP+G GP GP Sbjct: 829 GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPR 888 Query: 587 GAVVPLALQNEPTPAPEDNGCPP 609 G+ +P P G P Sbjct: 889 GSRGARGPTGKPGPKGTSGGDGP 911 Score = 144 bits (362), Expect = 4e-34 Identities = 84/189 (44%), Positives = 97/189 (51%), Gaps = 32/189 (16%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 L G G G +G G QGPPGP G+ G++G G GP G G GP GP GP GE+G G Sbjct: 1034 LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1093 Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP---PGKEGLPGPQGPPGFQGLQGTVGEPG 557 KG QGP G + G QGP G PGP GP PG++G G G PG +G +G GE G Sbjct: 1094 EKGPQGPAG------RDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1147 Query: 558 VPGPRGLPGLPGVPGMPGPKGPPGP------------------PGPSGAVVPLALQNEPT 599 PGP GL G G PG+ G G PGP PGP G P+ LQ P Sbjct: 1148 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG---PIGLQGLPG 1204 Query: 600 PAPE--DNG 606 P E +NG Sbjct: 1205 PPGEKGENG 1213 Score = 142 bits (359), Expect = 9e-34 Identities = 83/193 (43%), Positives = 96/193 (49%), Gaps = 45/193 (23%) Query: 440 ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP----PGE 495 +++GPPGP GP G G G GPTG G G++G PG PG G G GP G P Sbjct: 439 LVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFR 498 Query: 496 RGGKGSKGS--------------------QGPKGSRGSPGKPGP---------QGPSGDP 526 GG GSKG +GP G G G+PGP +G SGDP Sbjct: 499 YGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDP 558 Query: 527 GPPGPPGKEGLPGPQGPPGFQGL------QGTVGEPGVPGPRGLPGLPGVP------GMP 574 GP GP G +G PGP G PG +G +G GEPG G RG GLPG+P G Sbjct: 559 GPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER 618 Query: 575 GPKGPPGPPGPSG 587 GP+GPPGPPG G Sbjct: 619 GPQGPPGPPGDDG 631 Score = 142 bits (359), Expect = 9e-34 Identities = 77/158 (48%), Positives = 88/158 (55%), Gaps = 9/158 (5%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +GPPG GP G +G G PGP G +G G GE G PG AG+ GP GP GPPG G KG Sbjct: 1386 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD 1445 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGP---PGFQGLQGTVGEPGV 558 GS+G KG G G GP G G+ G G PG +G PG +G PG G G G PG+ Sbjct: 1446 PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL 1505 Query: 559 PGPRGLPGLPGVPGMPGPK------GPPGPPGPSGAVV 590 PGP+G G G G G K GPPG PGP G V+ Sbjct: 1506 PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVI 1543 Score = 142 bits (358), Expect = 1e-33 Identities = 81/172 (47%), Positives = 89/172 (51%), Gaps = 12/172 (6%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 LQGP G G G G GP G G GQKG++G G PGP G G G GPPGE+ G Sbjct: 1154 LQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK---G 1210 Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL---PGPQGPPGFQGLQGTVGEPG 557 G GP G G PG GPQGP+G GP GPPG G G +G PG G G GE G Sbjct: 1211 ENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1270 Query: 558 VPGP------RGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPE 603 V GP +G G PG G PG KGPPG GP G P+ +P P E Sbjct: 1271 VGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1322 Score = 141 bits (355), Expect = 2e-33 Identities = 78/173 (45%), Positives = 93/173 (53%), Gaps = 15/173 (8%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGP---AGPPGERG 497 + GPPGP+G G +G GPPG GN G +G G GP GP GE+GP G AG PG G Sbjct: 671 VDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADG 730 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGP---------PGFQ- 547 G G +G G +G+ G PGPQGP G PGP G G +G+ G +G PGF+ Sbjct: 731 PPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKG 790 Query: 548 --GLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598 GL+G GE G GPRG G G G GP G PGP G +G L + P Sbjct: 791 DMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLP 843 Score = 136 bits (343), Expect = 6e-32 Identities = 72/142 (50%), Positives = 83/142 (58%), Gaps = 6/142 (4%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 + GP G +G G G GPPGP G G G KG+PG G G G IG GPPGE+G KG Sbjct: 1412 IPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKG 1471 Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPG 560 +G G +GS G+ G G GP+G GPPGPP GLPGPQGP +G +G+ G G G Sbjct: 1472 DRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP---GLPGPQGP---KGNKGSTGPAGQKG 1525 Query: 561 PRGLPGLPGVPGMPGPKGPPGP 582 GLPG PG PG PG P P Sbjct: 1526 DSGLPGPPGSPGPPGEVIQPLP 1547 Score = 99.8 bits (247), Expect = 8e-21 Identities = 76/199 (38%), Positives = 86/199 (43%), Gaps = 46/199 (23%) Query: 447 PRGPRGDRGSQGPPGPT----------GNKGQKGEKGEP----------GPPGPAGERGP 486 P P + G P T G G+KG+KGEP GPPGPAG P Sbjct: 393 PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAG---P 449 Query: 487 IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP----PGKEGLPGPQG 542 G GPPG +G G G G RG PG+PG G G PGPPG P + G G +G Sbjct: 450 AGIMGPPGLQGPTGPPGDPG---DRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKG 506 Query: 543 PP------GFQGL--QGTVGEPGVPGPRGLPGLPGV---PGMPGPKGPPGPPGPSGAVVP 591 P Q + Q + G PGP GL G PG PG G KG G PGP G P Sbjct: 507 PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQG---P 563 Query: 592 LALQNEPTPA--PEDNGCP 608 +Q P P P G P Sbjct: 564 RGVQGPPGPTGKPGKRGRP 582 Score = 53.9 bits (128), Expect = 5e-07 Identities = 23/45 (51%), Positives = 29/45 (64%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI 487 G PGP+GP+G++GS GP G G+ G G G PGPPG + PI Sbjct: 1504 GLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPI 1548 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 168 bits (426), Expect = 1e-41 Identities = 89/185 (48%), Positives = 106/185 (57%), Gaps = 22/185 (11%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG------- 494 +G G RG +G+RG G PG G+ GQ+G G G GP GE+G +GPAGPPG Sbjct: 592 RGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQ 651 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPG------PQGPPGFQG 548 + G KG +G+ GP+G +G+PG PG +GP G G GPPG +GL G P G PG G Sbjct: 652 QEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLG 711 Query: 549 LQGTVGEPGVPGPRG------LPG---LPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPT 599 LQG G PGVPGP G LPG PG PG PGP GPPG GP+G P + EP Sbjct: 712 LQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPG 771 Query: 600 PAPED 604 ED Sbjct: 772 ERGED 776 Score = 159 bits (403), Expect = 7e-39 Identities = 85/174 (48%), Positives = 98/174 (56%), Gaps = 13/174 (7%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GPPG G G +G +G PG G +G +G+KGE GPPG G P G AGP G +G +G+ Sbjct: 1120 GPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPG---PPGIAGPQGSQGERGAD 1176 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G G KG +G PG PG GP PG PGPPG +G+ G GPPG QG G G PG GP Sbjct: 1177 GEVGQKGDQGHPGVPGFMGP---PGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPS 1233 Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP-TPAPEDNGCPPHWKNFT 615 GLPG+PG G G G PGPPG G EP P PE PP +K T Sbjct: 1234 GLPGIPGEEGKEGRDGKPGPPGEPGKA------GEPGLPGPEGARGPPGFKGHT 1281 Score = 157 bits (397), Expect = 3e-38 Identities = 82/176 (46%), Positives = 99/176 (56%), Gaps = 30/176 (17%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPG---PAGERGPIGPAGPPGERGG 498 +GPPG +G GD G+ GP G +G G G++G PG G P G +GP GP GPPG+ G Sbjct: 1272 RGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGS 1331 Query: 499 KGSKGSQGP---------KGSRGSPGKP---GPQGPSGDPGPPGPPGKEGLPGPQGPPGF 546 GS G GP KG GSPG P GP+GP G+PG G PGKEG+PG G PGF Sbjct: 1332 PGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGF 1391 Query: 547 QGL---------------QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 +G +G G+PG+PG +G GL G G+PG GP GPPGP G Sbjct: 1392 KGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPG 1447 Score = 155 bits (391), Expect = 2e-37 Identities = 85/186 (45%), Positives = 97/186 (52%), Gaps = 28/186 (15%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKG------EPGPPGPAGERGPIGPAGPPG 494 L GPPG GP+G +G +G G G KG +G G PG PGP G G G AGPPG Sbjct: 1157 LPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPG 1216 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSG---DPGPPGPPGKEG---LPGPQGPPGFQG 548 +G G +G GP+G G PG PG +G G PGPPG PGK G LPGP+G G G Sbjct: 1217 IQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPG 1276 Query: 549 LQGTVGEPGVPGPR------GLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAP 602 +G G+ G PGPR GLPG G+PG G GP GP GP G P P Sbjct: 1277 FKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQG----------PRGPP 1326 Query: 603 EDNGCP 608 NG P Sbjct: 1327 GKNGSP 1332 Score = 152 bits (385), Expect = 8e-37 Identities = 80/158 (50%), Positives = 93/158 (58%), Gaps = 12/158 (7%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 QG PGP G RG G +G GP G +G +G+KG+ GPPG G G GP GPPG G G Sbjct: 668 QGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGP 727 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDP------GPPGPPGKEGLPGPQGP---PGFQGLQGT 552 GS G G G PGKPGP GP+G P GPPGPPG +G PG +G PG GL+G Sbjct: 728 GGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGE 787 Query: 553 VGEPGV---PGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 +GE G+ PG +G GLPG PG PG +G G G G Sbjct: 788 IGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKG 825 Score = 151 bits (381), Expect = 2e-36 Identities = 79/157 (50%), Positives = 85/157 (54%), Gaps = 12/157 (7%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG---------PPGPAGERGPIGPAGPP 493 GPPG RGP G G GPPG G +G+KG+ G PG PPGP G GP GP G P Sbjct: 672 GPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSP 731 Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGK---EGLPGPQGPPGFQGLQ 550 G G G G GP G G PGK GP GP G PG G PG+ +GLPG G G G Q Sbjct: 732 GLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQ 791 Query: 551 GTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G G PG G GLPG PG PG+ G KG G G G Sbjct: 792 GLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELG 828 Score = 150 bits (380), Expect = 3e-36 Identities = 78/147 (53%), Positives = 85/147 (57%), Gaps = 3/147 (2%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GPPG GP G G QG G G G+ G+KG+ G PG G GP G GPPG G G+ Sbjct: 1153 GPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAA 1212 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G G +GS G G PGPQGPSG PG PG GKEG G GPP G G GEPG+PGP Sbjct: 1213 GPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPP---GEPGKAGEPGLPGPE 1269 Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSGAV 589 G G PG G G G PGP G SGA+ Sbjct: 1270 GARGPPGFKGHTGDSGAPGPRGESGAM 1296 Score = 149 bits (377), Expect = 7e-36 Identities = 74/159 (46%), Positives = 92/159 (57%), Gaps = 12/159 (7%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG------PIGPAGPPG 494 +QG PG GP G +G G PG G +G++G G+PGPPG G+ G P G GPPG Sbjct: 1217 IQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPG 1276 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVG 554 +G G G+ GP+G G+ G PG +G G G GP G +G GP+GPPG G G+ G Sbjct: 1277 FKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPG 1336 Query: 555 EPG---VPGPRGLPG---LPGVPGMPGPKGPPGPPGPSG 587 EPG PG +G G PG+PG GP+GPPG PG G Sbjct: 1337 EPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKG 1375 Score = 148 bits (374), Expect = 2e-35 Identities = 80/174 (45%), Positives = 93/174 (53%), Gaps = 10/174 (5%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP---PGERGGK 499 GPPG G G+ G GP G G G KG G+ G PGP GE G +G G PG+ G Sbjct: 1252 GPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDT 1311 Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559 G G QGP+G RG PGK G G G+PGP G PG++G G G PG G G G PG P Sbjct: 1312 GPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEP 1371 Query: 560 GPRGLP---GLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPPH 610 G +G+P G+PG PG PG KG G PG G P + + P D G P H Sbjct: 1372 GEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQ----PGDPGIPGH 1421 Score = 148 bits (373), Expect = 2e-35 Identities = 84/179 (46%), Positives = 94/179 (52%), Gaps = 34/179 (18%) Query: 443 GPPGPRGPRGDRGSQGPPGPTG-------NKGQKGEKGEPGP------PGPAGERGPIGP 489 GP G GP+G++G GP GP G +G KGE+G PGP PGP G RGPIGP Sbjct: 623 GPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGP 682 Query: 490 AG---PPGERGGKGSKGSQGP---------KGSRGSPGKPGPQGPSGDPG---------P 528 G PPG +G +G KG GP +G G PG PGP GP G PG Sbjct: 683 EGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGK 742 Query: 529 PGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 PGPPG G PG GP G G GT GEPG G GLPG PG+ G G +G G PG G Sbjct: 743 PGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKG 801 Score = 148 bits (373), Expect = 2e-35 Identities = 79/175 (45%), Positives = 93/175 (53%), Gaps = 30/175 (17%) Query: 443 GPPGPRGPRGDRGSQGPPGPTG----------------NKGQKGEKGEPGPPGPAG---- 482 G PG +G RG++G GP GP G +G KGEKG+PG PG G Sbjct: 828 GLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGR 887 Query: 483 --ERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP 540 E GP GP GPPG +G +G+ G+ G G+ G+PG G GPSG PG G PG G PG Sbjct: 888 PGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGK 947 Query: 541 QGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGP--------KGPPGPPGPSG 587 G G +G G G PG GPRG PG PG+PG PG +G PG PGP G Sbjct: 948 DGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLG 1002 Score = 147 bits (372), Expect = 3e-35 Identities = 85/183 (46%), Positives = 95/183 (51%), Gaps = 38/183 (20%) Query: 443 GPPGPRGPRGD-------------RGSQGPPGPTGNKGQKG------EKGEPGPPGPAGE 483 G PGP+G +GD +GS G PGP G G KG E GEPG PG G Sbjct: 508 GAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGM 567 Query: 484 RGPIGPAGPPG------------ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGP--- 528 RGP GP G PG ERG KG++G +G +G G PGKPG G G PGP Sbjct: 568 RGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGV 627 Query: 529 PGPPGKEGLPGPQGPPGFQG----LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPG 584 GP G++G GP GPPG G +G GE G PGPRG G PG PG GP GP G G Sbjct: 628 AGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDG 687 Query: 585 PSG 587 P G Sbjct: 688 PPG 690 Score = 146 bits (368), Expect = 8e-35 Identities = 87/197 (44%), Positives = 93/197 (47%), Gaps = 52/197 (26%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGP---AGPPGERGG- 498 GPPGP GP G G GPPGP G KG+ GE+GE G PG G RG IG AG PGE+G Sbjct: 744 GPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEA 803 Query: 499 -----------KGSKGSQGPKGSRGSPG-------------------------------K 516 +G KG QG KG G PG Sbjct: 804 GLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRM 863 Query: 517 PGPQGP---SGDPGPPGPPGKEGLP---GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGV 570 PG QGP GDPG PG PG +G P GPQGP G G +G G G PG G PG PG Sbjct: 864 PGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGH 923 Query: 571 PGMPGPKGPPGPPGPSG 587 G PGP GPPG G G Sbjct: 924 VGAPGPSGPPGSVGAPG 940 Score = 144 bits (364), Expect = 2e-34 Identities = 76/165 (46%), Positives = 90/165 (54%), Gaps = 1/165 (0%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKG-EPGPPGPAGERGPIGPAGPPGERGGKGS 501 GP G GP+GD G+ GP G G KG+KG+ G P G GE+G +G GPPG G KG Sbjct: 490 GPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGM 549 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGP 561 +G G G G PG+ G +GP G PG PGPPG+ G PG QG G +G +G GE G+ G Sbjct: 550 RGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGF 609 Query: 562 RGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNG 606 G PG G G PGP G GP G G V P P + G Sbjct: 610 PGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEG 654 Score = 144 bits (362), Expect = 4e-34 Identities = 78/183 (42%), Positives = 94/183 (51%), Gaps = 36/183 (19%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKG------QKGEKGEPGPPGPAGE---------RG 485 + G GP G +G G +GPPGP G G ++G++G G PGP GE G Sbjct: 1208 IAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPG 1267 Query: 486 PIGPAGPPGERGGKGSKGSQGPKGSRGSPGKP------------------GPQGPSGDPG 527 P G GPPG +G G G+ GP+G G+ G P GPQGP G PG Sbjct: 1268 PEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPG 1327 Query: 528 PPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP---GPRGLPGLPGVPGMPGPKGPPGPPG 584 G PG G PGP G PG +G +G G PG+P GPRG PG PG G+PG +G PG PG Sbjct: 1328 KNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPG 1387 Query: 585 PSG 587 G Sbjct: 1388 EPG 1390 Score = 143 bits (360), Expect = 7e-34 Identities = 85/196 (43%), Positives = 97/196 (49%), Gaps = 36/196 (18%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGPPGE-- 495 L G PG +G G+ G QGP GP G KGQ+G G PG PG G G GP+GPPG Sbjct: 878 LPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVG 937 Query: 496 ----RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPP-----GKEGLPGPQGPPGF 546 RG G G +G KG+ G G PGP GP GDPG PG P GK+G PG +G PG Sbjct: 938 APGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGL 997 Query: 547 QGLQGT--------------VGEPGVPGPRGLPGLPGVP--------GMPGPKGPPGPPG 584 G GT +G V G RG PG+PG P G+ GP GP GPPG Sbjct: 998 PGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPG 1057 Query: 585 PSGAVVPLALQNEPTP 600 G+ L P P Sbjct: 1058 DKGSPGSRGLPGFPGP 1073 Score = 143 bits (360), Expect = 7e-34 Identities = 76/149 (51%), Positives = 84/149 (56%), Gaps = 12/149 (8%) Query: 442 QGPPGPRGP---RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498 QGP GPRGP G GS G PGP+G GQKG KGE G PG G GP GP G PGE+ Sbjct: 1317 QGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEK-- 1374 Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV 558 G G G PGKPG G G+ G PG G +G PG +G PG G+ G G G+ Sbjct: 1375 -------GVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGL 1427 Query: 559 PGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 GP+GLPG G G PGP G PG PG G Sbjct: 1428 MGPQGLPGENGPVGPPGPPGQPGFPGLRG 1456 Score = 142 bits (359), Expect = 9e-34 Identities = 74/147 (50%), Positives = 84/147 (57%), Gaps = 6/147 (4%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 LQGPPGP G GPPGP G+ G GE G PG PGP G GP G GP G G G Sbjct: 712 LQGPPGPPGV------PGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPG 765 Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPG 560 +KG G +G G PGKPG +G G+ G G PG++G G G PGF G++G G+ G G Sbjct: 766 TKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKG 825 Query: 561 PRGLPGLPGVPGMPGPKGPPGPPGPSG 587 GLPGL G G G GP GPPG G Sbjct: 826 ELGLPGLKGDRGEKGEAGPAGPPGLPG 852 Score = 141 bits (355), Expect = 2e-33 Identities = 85/202 (42%), Positives = 95/202 (47%), Gaps = 35/202 (17%) Query: 432 GQLIKNFTILQGPPGPRGPRGD-----RGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP 486 GQ +K G PG G RGD G GP GP G+KG G +G PG PGP G G Sbjct: 1020 GQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGR 1079 Query: 487 IGPAGPPGERG--GK----------------------------GSKGSQGPKGSRGSPGK 516 G G PGERG GK G G G KG +G PGK Sbjct: 1080 DGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGK 1139 Query: 517 PGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGP 576 PG +G G G GPPG G PG GP G QG +G GE G G +G PG+PG G PG Sbjct: 1140 PGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGN 1199 Query: 577 KGPPGPPGPSGAVVPLALQNEP 598 GPPG G +GA P +Q P Sbjct: 1200 PGPPGADGIAGAAGPPGIQGSP 1221 Score = 140 bits (353), Expect = 4e-33 Identities = 87/217 (40%), Positives = 101/217 (46%), Gaps = 50/217 (23%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PGP G G +G +G PG G G GE G GP GP G GP G G PG +G +G K Sbjct: 536 GLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEK 595 Query: 503 GSQGPKGSRG------------SPGKP------GPQGPSGDPGPPGPPG-------KEGL 537 G++G KG RG G+P GPQG GD GP GPPG +EGL Sbjct: 596 GTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGL 655 Query: 538 PGPQGPPGFQGLQGTVGEPGV------------------------PGPRGLPGLPGVPGM 573 G QG PG +G QG G PG GP G+PGL G+ G Sbjct: 656 KGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGP 715 Query: 574 PGPKGPPGPPGPSGAV-VPLALQNEPTPAPEDNGCPP 609 PGP G PGPPGP G+ +P + P P PP Sbjct: 716 PGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPP 752 Score = 140 bits (352), Expect = 6e-33 Identities = 83/188 (44%), Positives = 89/188 (47%), Gaps = 37/188 (19%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE---PGPPGPAGERGPIGPAGPPGERG 497 L G PG +G G G+ G PG G KG +GEKGE PG G GE+G GPAGPPG G Sbjct: 793 LAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPG 852 Query: 498 GKG-------SKGSQGPKGSRGSPGKPG------------PQGPSGDPGP---------- 528 G QGPKG +G PG PG PQGP+G PG Sbjct: 853 TTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAP 912 Query: 529 -----PGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPP 583 PG PG G PGP GPPG G G G PG G RG G G G PGP GP G P Sbjct: 913 GAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDP 972 Query: 584 GPSGAVVP 591 G G P Sbjct: 973 GAPGLPGP 980 Score = 137 bits (346), Expect = 3e-32 Identities = 87/213 (40%), Positives = 99/213 (46%), Gaps = 57/213 (26%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGN--KGQKGEKGEPGPPGPAGERGPIGPA--------G 491 +G PGP GPRGD G+ G PGP G G+ G +G PG PGP G + G G Sbjct: 960 EGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALG 1019 Query: 492 PPGERGGKGSKGSQGPKGSRGSPG-----KPGPQGPSGDPGPPGPPGKEGLPGPQGP--- 543 +G +G+ G G GSRG PG PGP GP GD G PG G G PGPQGP Sbjct: 1020 GQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGR 1079 Query: 544 ---PGFQGLQGTVGEPGV---------------------PGPRGLPGLP------GVPGM 573 PG G +G G+PG+ PGP GLPGLP GVPG Sbjct: 1080 DGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGK 1139 Query: 574 PGPK---------GPPGPPGPSGAVVPLALQNE 597 PG + GPPG PGP G P Q E Sbjct: 1140 PGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGE 1172 Score = 135 bits (341), Expect = 1e-31 Identities = 86/234 (36%), Positives = 102/234 (43%), Gaps = 60/234 (25%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG---------PPGPAGERGPIGPAGPP 493 G PG +G RGD G +G GP G KGQ G+ G PG P G GE GP+GP GPP Sbjct: 1387 GEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPP 1446 Query: 494 GERGGKGSKGSQG-----------------------------PKGSRGSPGKPGPQGP-- 522 G+ G G +G P + S G+PGP GP Sbjct: 1447 GQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPG 1506 Query: 523 -------SGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP-----GPRGLPGLPGV 570 +G G PG PG+ GL GP GP G +G +G G+PG P G G PG+PG Sbjct: 1507 KDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQ 1566 Query: 571 PGMPG--PKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPPHWKNFTDKCYYFS 622 PG PG G PG PGP G P P P C P +C YF+ Sbjct: 1567 PGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDP------SQCAYFA 1614 Score = 134 bits (338), Expect = 2e-31 Identities = 78/163 (47%), Positives = 87/163 (53%), Gaps = 9/163 (5%) Query: 447 PRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP--IGPAGPPGERGGKGSKGS 504 P G +G+ G GP G G KG G G G PGP GE+G IGP G GE+G KGS G Sbjct: 479 PAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFG-QGEKGEKGSLGL 537 Query: 505 QGP------KGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV 558 GP KG RG PG+ G G G+ G GP G GLPGP G G GLQG GE G Sbjct: 538 PGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGT 597 Query: 559 PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601 G +G GL G PG PG G G PGPSG P + + PA Sbjct: 598 RGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPA 640 Score = 113 bits (283), Expect = 6e-25 Identities = 65/148 (43%), Positives = 79/148 (53%), Gaps = 16/148 (10%) Query: 425 KLVDSKHGQLIKN---FTILQGPPG-PRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGP 480 +L+ + G+ ++ + + Q PP + +G G GPPG G G+ G GEPG PG Sbjct: 1466 RLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQ 1525 Query: 481 AGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPG--KEGLP 538 G GP GP GP GERG KG G+ G G G GP G PG PG PG K+GLP Sbjct: 1526 GGLEGPSGPIGPKGERGAKGDPGAPG-------VGLRGEMGPPGIPGQPGEPGYAKDGLP 1578 Query: 539 GPQGPPGFQGLQGTVGEPGVPGPRGLPG 566 G GP QG G G PG+PGP G PG Sbjct: 1579 GIPGP---QGETGPAGHPGLPGPPGPPG 1603 Score = 54.3 bits (129), Expect = 4e-07 Identities = 44/153 (28%), Positives = 51/153 (33%), Gaps = 74/153 (48%) Query: 519 PQGPSG-----DPGPPGPP--------------------------GKEGLPGPQGPPGFQ 547 P GP +P PP PP G+ G+ GP G PG + Sbjct: 439 PSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPK 498 Query: 548 GLQGTVGEPGVPGPR-------------------------------------------GL 564 G G +G G PGP+ G Sbjct: 499 GDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGE 558 Query: 565 PGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNE 597 PGLPG GM GP+GPPG PGP G V LQ E Sbjct: 559 PGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGE 591 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 168 bits (425), Expect = 2e-41 Identities = 78/148 (52%), Positives = 92/148 (62%), Gaps = 3/148 (2%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GPPGP G G G+ G PG G +G+ G+KG+ G PGP G G GP GP G G KG++ Sbjct: 828 GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 887 Query: 503 GSQGPKGSRGSPG---KPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559 G+QGP G+ G PG + GP G +G+PGPPGPPG G GP+G G G G GEPG+ Sbjct: 888 GAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQ 947 Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 GP G PG G PG GP G GPPGP G Sbjct: 948 GPAGPPGEKGEPGDDGPSGAEGPPGPQG 975 Score = 163 bits (412), Expect = 6e-40 Identities = 82/159 (51%), Positives = 93/159 (58%), Gaps = 12/159 (7%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 QGP G GP+G RG+QGPPG T G G G GPPG G GP GP GP G+ G KG+ Sbjct: 875 QGPTGVTGPKGARGAQGPPGAT---GFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA 931 Query: 502 KGSQGPKGSRGSPGKPGPQGP---SGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGE--- 555 +G GP G G PG GP GP G+PG GP G EG PGPQG G +G+ G G+ Sbjct: 932 RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGE 991 Query: 556 ---PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 PG+PGP G PG G PG G +GPPGP GP G P Sbjct: 992 RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGP 1030 Score = 161 bits (408), Expect = 2e-39 Identities = 83/165 (50%), Positives = 92/165 (55%), Gaps = 9/165 (5%) Query: 443 GPPGPRGPRGDRGSQGPPGP---TGNKGQKGEKGEPGPPG------PAGERGPIGPAGPP 493 GPPGP+G RG G G PGP G G+ GEKG PG PG GE G GP GP Sbjct: 588 GPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPA 647 Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553 G G +G +G+ GP G +G PG PGP G G PG G PG+ G PG GP G +G G Sbjct: 648 GPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGER 707 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598 G PG G +G GLPG PG GPKG GP GP GA P LQ P Sbjct: 708 GSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMP 752 Score = 160 bits (405), Expect = 4e-39 Identities = 79/160 (49%), Positives = 95/160 (59%), Gaps = 15/160 (9%) Query: 443 GPPGPRGPRGDRGSQG------------PPGPTGNKGQKGEKGEPGPPGPAGERGPIGPA 490 GPPGP GP G+RG QG PPGP G G+ G++G PG G G GP G Sbjct: 642 GPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGER 701 Query: 491 GPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPG---PPGKEGLPGPQGPPGFQ 547 G PGERG G++G QGP+G G+PG GP+G SG GPPG PPG +G+PG +G G Sbjct: 702 GFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIA 761 Query: 548 GLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G +G G+ G GP G PG G G+ GP GPPGP G +G Sbjct: 762 GPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANG 801 Score = 159 bits (403), Expect = 7e-39 Identities = 84/174 (48%), Positives = 93/174 (53%), Gaps = 15/174 (8%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PGP GPRG G +G GP G G +G G+PGP GP G P+GPAG PG G G+K Sbjct: 318 GSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPG---PVGPAGGPGFPGAPGAK 374 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT---VGEPGVP 559 G GP G+RG G GP+G G PG PGP G G PG G PG +G G G PG P Sbjct: 375 GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP 434 Query: 560 GPRGLPGLPGVPGMPGPKGPPGPP---------GPSGAVVPLALQNEPTPAPED 604 GPRG PG G G GPKG G P GP G P Q P PA E+ Sbjct: 435 GPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEE 488 Score = 157 bits (398), Expect = 3e-38 Identities = 86/210 (40%), Positives = 105/210 (50%), Gaps = 37/210 (17%) Query: 435 IKNFTILQGPPGPRGP---------RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG 485 IK+ +GPPGP+GP RGD+G +G PGP G G+ G G PGPPGP G G Sbjct: 112 IKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPG 171 Query: 486 P---------------------------IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPG 518 P GP GP G RG G G+ GP+G +G+PG+PG Sbjct: 172 PPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG 231 Query: 519 PQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKG 578 G SG GP GPPG G PG G G G G G PG G RG PG PG+PG+ G +G Sbjct: 232 EPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRG 291 Query: 579 PPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 PG G G ++ E + +P +NG P Sbjct: 292 YPGLDGAKGEAGAPGVKGE-SGSPGENGSP 320 Score = 157 bits (398), Expect = 3e-38 Identities = 86/193 (44%), Positives = 102/193 (52%), Gaps = 36/193 (18%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQ------KGE------KGEPGPPGPAGERGPIGP 489 +GPPGP+G RG G+ G PG G++G KGE KGE G PG G GP+GP Sbjct: 266 RGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP 325 Query: 490 AGPPGERGGKGSKGSQGPKGSRGSPGK---PGPQGPSGDPGPPGPPGKEGLPGPQGPPGF 546 G PGERG G G+ G +G+ G PG PGP GP+G PG PG PG +G GP G G Sbjct: 326 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 385 Query: 547 QGLQGTVGEPGVP---------------------GPRGLPGLPGVPGMPGPKGPPGPPGP 585 +G QG GEPG P G G PG+ G PG PGP+GPPGP G Sbjct: 386 EGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGA 445 Query: 586 SGAVVPLALQNEP 598 +G + P EP Sbjct: 446 TGPLGPKGQTGEP 458 Score = 157 bits (396), Expect = 4e-38 Identities = 87/182 (47%), Positives = 99/182 (54%), Gaps = 36/182 (19%) Query: 442 QGPPGPRG---PRGDRGSQGPPGPTGNKGQKGEKGEPGP------PGPAGERGP------ 486 +GPPGP+G P G +G G PG G KG++G KGEPGP PGPAGE G Sbjct: 437 RGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGE 496 Query: 487 ---IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGP------PGPPGKEGL 537 +GP GPPGERG G++G G G G G PG +GPSG GP PG PG+ GL Sbjct: 497 PGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGL 556 Query: 538 P------------GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGP 585 P GPQG G G G G PG PGP+G G PGV G PGPKG G PG Sbjct: 557 PGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGK 616 Query: 586 SG 587 +G Sbjct: 617 AG 618 Score = 155 bits (393), Expect = 1e-37 Identities = 89/202 (44%), Positives = 102/202 (50%), Gaps = 35/202 (17%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG------------PPGPAGERGPIGP 489 QG PGP G G RG++G PG G G GE+G PG P G GERGP G Sbjct: 479 QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGL 538 Query: 490 AGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPG---- 545 AGP G G G G G G+RG G+PG GP G GP G PG++G PGP GP G Sbjct: 539 AGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ 598 Query: 546 -----FQGLQGTVGEPGVPGPRGLPGLPGVPGMP------GPKGPPGPPGPS------GA 588 F G +G GEPG G +GLPG PG+ G+P G GPPGP GP+ GA Sbjct: 599 PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 658 Query: 589 VVPLALQNEPTP--APEDNGCP 608 P Q P P P + G P Sbjct: 659 PGPSGFQGLPGPPGPPGEGGKP 680 Score = 155 bits (393), Expect = 1e-37 Identities = 84/175 (48%), Positives = 96/175 (54%), Gaps = 7/175 (4%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG---PIGPAGPPGERGG 498 QGPPG +G G+RG+ G GP G++G GEKG G PG G RG PIGP GP G G Sbjct: 743 QGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGE 802 Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPG---PPGKEGLPGPQGPPGFQGLQGTVGE 555 KG G GP GS G+ G PG +G +G PGP G PPG +G PG +G G G +G G Sbjct: 803 KGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGA 862 Query: 556 PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAV-VPLALQNEPTPAPEDNGCPP 609 PG GP G PG G G+ GPKG G GP GA P A P N PP Sbjct: 863 PGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPP 917 Score = 155 bits (392), Expect = 1e-37 Identities = 77/157 (49%), Positives = 87/157 (55%), Gaps = 6/157 (3%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PG GP G G GP G G++G+ G +G GP GPAG RG GP GP G++G G Sbjct: 1065 GAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEP 1124 Query: 503 GSQGPKGSRGS------PGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G +G KG RG PG PGP G G GP GP G G PGP GP G G G G Sbjct: 1125 GERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPI 1184 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLA 593 G PGPRG G G G PG GPPGPPGP G + ++ Sbjct: 1185 GPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMS 1221 Score = 155 bits (391), Expect = 2e-37 Identities = 83/170 (48%), Positives = 91/170 (53%), Gaps = 7/170 (4%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +GP G G G RG GP GP G G GEKGE GPPGPAG G G G GE G G Sbjct: 773 KGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP 832 Query: 502 KGSQGPKGSRGSPGKPGPQGPSG---DPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV 558 G GP G+ G PG G QG +G D G PGP G G PGPQGP G G +G G G Sbjct: 833 AGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP 892 Query: 559 PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 PG G PG G G PG G PGPPGP G + ++ P A D+G P Sbjct: 893 PGATGFPGAAGRVGPPGSNGNPGPPGPPGP----SGKDGPKGARGDSGPP 938 Score = 155 bits (391), Expect = 2e-37 Identities = 85/181 (46%), Positives = 95/181 (52%), Gaps = 36/181 (19%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGER---GGK 499 G GP G G+ G GPPGP+G G KG +G+ GPPG AGE G GPAGPPGE+ G Sbjct: 903 GRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDD 962 Query: 500 GSKGSQGP------------------KGSRGSPGKPGPQ---------GPSGDPGPPGPP 532 G G++GP +G RG PG PGP G SGD GPPGP Sbjct: 963 GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPV 1022 Query: 533 GKEGLPGPQGPPGFQGLQGTVGEP------GVPGPRGLPGLPGVPGMPGPKGPPGPPGPS 586 G GL GP G PG +G G G P GV G RG G G PG PGP G PGP GP+ Sbjct: 1023 GPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPT 1082 Query: 587 G 587 G Sbjct: 1083 G 1083 Score = 154 bits (390), Expect = 2e-37 Identities = 83/181 (45%), Positives = 93/181 (51%), Gaps = 21/181 (11%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE------PGPPGPAGERGPIGPAGPPG 494 L GP G G G G+ GPPG G G KG++GE PG PGP G GP GP G G Sbjct: 1027 LTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1086 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGK------------EGLPGPQG 542 +RG G++G GP G G+ G GPQGP GD G G PG+ +GLPGP G Sbjct: 1087 DRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPG 1146 Query: 543 PPGFQGLQGTVGEPGV---PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPT 599 P G QG G G G PGP G G G G+PGP GPPGP G SG P P Sbjct: 1147 PSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPG 1206 Query: 600 P 600 P Sbjct: 1207 P 1207 Score = 151 bits (381), Expect = 2e-36 Identities = 78/178 (43%), Positives = 93/178 (52%), Gaps = 18/178 (10%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 + GP G RG G++G +G PG G +G G G PGP G GE+G +GP GP G G +G Sbjct: 760 IAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARG 819 Query: 501 SKGSQ------------GPKGSRGSPGKPGPQGPS---GDPGPPGPPGKEGLPGPQGPPG 545 + G + GP G+ G PG G QG + GD G PGP G G PGPQGP G Sbjct: 820 APGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTG 879 Query: 546 FQGLQGTVGEPGVPGPRGLPGLP---GVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP 600 G +G G G PG G PG G PG G GPPGPPGPSG P + + P Sbjct: 880 VTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGP 937 Score = 150 bits (378), Expect = 5e-36 Identities = 80/169 (47%), Positives = 89/169 (52%), Gaps = 24/169 (14%) Query: 440 ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499 ++QGP GP GPRG G G PGP G +G GE GEPG GP G RGP GPPG+ G Sbjct: 198 VMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGP---PGPPGKPGDD 254 Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP------PGKEGLPGPQGPPGFQGLQGTV 553 G G G G RG PG G +G G PG PG PG +G G G PG +G G+ Sbjct: 255 GEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSP 314 Query: 554 GEPGVPGPRGLPGLPGV---------------PGMPGPKGPPGPPGPSG 587 GE G PGP G GLPG G PGP GPPGP GP+G Sbjct: 315 GENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAG 363 Score = 149 bits (377), Expect = 7e-36 Identities = 80/176 (45%), Positives = 94/176 (53%), Gaps = 10/176 (5%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +GP G +GPRG+ G+ G PGP G G G G PG G AG G G G PG RG G Sbjct: 383 RGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGP 442 Query: 502 KGSQGPKGSRGSPGKP------GPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGE 555 +G+ GP G +G G+P G QGP G+PGP GP G G G +G G +G G VG Sbjct: 443 QGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGP 502 Query: 556 PGVPGPRGLP---GLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 G PG RG P G PG G+ GPKG PG GPSG P +P P + G P Sbjct: 503 IGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDP-GRPGEPGLP 557 Score = 148 bits (373), Expect = 2e-35 Identities = 79/169 (46%), Positives = 96/169 (56%), Gaps = 16/169 (9%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PGPRGP G +G+ GP GP KG+ GEPG G GE+GP G GP G +G G Sbjct: 432 GFPGPRGPPGPQGATGPLGP------KGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA 485 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGP---PGKEGLPGPQGPPGFQGLQGTVGEPGVP 559 G +G +G+RG PG GP GP G+ G PG PG++GL GP+G PG +G G G G Sbjct: 486 GEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGAN 545 Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 G G PG PG+PG G G PG GP G V P+ AP ++G P Sbjct: 546 GDPGRPGEPGLPGARGLTGRPGDAGPQGKV-------GPSGAPGEDGRP 587 Score = 147 bits (372), Expect = 3e-35 Identities = 74/154 (48%), Positives = 85/154 (55%), Gaps = 22/154 (14%) Query: 456 SQGPPGPTGNKGQKGE-KGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSP 514 + G PGP G KG+ G+ K GP GP G +GP G GP G+RG KG KG+ GP+G G P Sbjct: 96 ASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 155 Query: 515 GKPGPQGPSGDPGPPGPPGKEG---------------------LPGPQGPPGFQGLQGTV 553 G PG GP G PGPPGPPG G + GP GP G +G G Sbjct: 156 GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 215 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G PG G +G PG PG PG+ GP GP GPPGP G Sbjct: 216 GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPG 249 Score = 147 bits (371), Expect = 3e-35 Identities = 77/172 (44%), Positives = 92/172 (53%), Gaps = 7/172 (4%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GP G GP G G+QGPPG G G++G G GP G G+ G GP G PG+ GG+G Sbjct: 729 GPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLT 788 Query: 503 GS---QGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559 G GP G+ G G+ GP GP+G G G PG+ G GP GP GF G G G+PG Sbjct: 789 GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAK 848 Query: 560 GPRGLPGLPGVPGMPGPKGP---PGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 G +G G G G PGP+GP PGP GP+G P + P P G P Sbjct: 849 GEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP-PGATGFP 899 Score = 146 bits (369), Expect = 6e-35 Identities = 79/175 (45%), Positives = 91/175 (52%), Gaps = 8/175 (4%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 QG PG G RG G GPPG TG G+ G +G PG GP G G G G GE G G+ Sbjct: 1007 QGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGA 1066 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPG------PPGPPGKEGLPGPQGPPGFQGLQGTVGE 555 G+ GP GS G G G QG G+ G P GP G G+ GPQGP G +G G GE Sbjct: 1067 PGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGE 1126 Query: 556 PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPED--NGCP 608 G+ G RG GL G+PG PGP G G GP+G P P+ +D NG P Sbjct: 1127 RGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIP 1181 Score = 146 bits (368), Expect = 8e-35 Identities = 78/162 (48%), Positives = 86/162 (53%), Gaps = 9/162 (5%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PG RG G G GP G G G GE G PGPPGP G RG G G PG +G G Sbjct: 555 GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEP 614 Query: 503 GSQGPKGS------RGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G G KG RG PGK G G +G PGP GP G+ G G GP GFQGL G G P Sbjct: 615 GKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPP 674 Query: 557 GV---PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQ 595 G PG +G+PG G PG+ GP+G G PG G+ LQ Sbjct: 675 GEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQ 716 Score = 145 bits (365), Expect = 2e-34 Identities = 73/148 (49%), Positives = 86/148 (58%), Gaps = 3/148 (2%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PG GPRG+RG G G G +G +G +G PG PG G +G GPAGPPG +G G + Sbjct: 690 GAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQ 749 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKE---GLPGPQGPPGFQGLQGTVGEPGVP 559 G G +G+ G G G +G G+ GP G PGK+ GL GP GPPG G G GE G P Sbjct: 750 GMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPP 809 Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 GP G G G PG G GPPGP G +G Sbjct: 810 GPAGSAGARGAPGERGETGPPGPAGFAG 837 Score = 144 bits (363), Expect = 3e-34 Identities = 74/151 (49%), Positives = 85/151 (56%), Gaps = 6/151 (3%) Query: 443 GPPGPRGPRGDRGSQGPPG------PTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGER 496 GPPGP GP G G G PG PTG +G +G +G G PG G GP G +G PG Sbjct: 354 GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTD 413 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G G+KGS G G G+PG PGP+GP G G GP G +G G G GF+G QG GEP Sbjct: 414 GIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 473 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G GP+G PG G G G +G PG GP G Sbjct: 474 GPAGPQGAPGPAGEEGKRGARGEPGGVGPIG 504 Score = 143 bits (361), Expect = 5e-34 Identities = 81/174 (46%), Positives = 89/174 (51%), Gaps = 24/174 (13%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG--- 498 +G PG RG G +G QGP G G G G KG GP GP G +GP G G PGERG Sbjct: 701 RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 760 Query: 499 ---KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL------PGPQGPPGFQGL 549 KG +G G KG G+PGK G +G +G GPPGP G G PGP G G +G Sbjct: 761 AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA 820 Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPK------------GPPGPPGPSGAVVP 591 G GE G PGP G G PG G PG K G PGP GPSGA P Sbjct: 821 PGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGP 874 Score = 142 bits (358), Expect = 1e-33 Identities = 85/201 (42%), Positives = 96/201 (47%), Gaps = 55/201 (27%) Query: 443 GPPGPR-------------GPRGDRGSQGP---PGPTGNKGQKGEKGEPGP------PGP 480 G PGP+ GP+G G QGP GP G++G KGEKG PGP PG Sbjct: 98 GQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT 157 Query: 481 AGERGPIGPAGPPG-----------------ERGG-------KGSKGSQGPKGSRGSPGK 516 G GP GP GPPG E+ G +G G GP+G G G Sbjct: 158 PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGA 217 Query: 517 PGPQGPSGDPGPPGPPGKEGLPGPQGPP---------GFQGLQGTVGEPGVPGPRGLPGL 567 PGPQG G+PG PG PG G GP+GPP G G G GE G PGP+G G Sbjct: 218 PGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGF 277 Query: 568 PGVPGMPGPKGPPGPPGPSGA 588 PG PG+PG KG G PG GA Sbjct: 278 PGTPGLPGVKGHRGYPGLDGA 298 Score = 137 bits (345), Expect = 4e-32 Identities = 69/145 (47%), Positives = 81/145 (55%), Gaps = 6/145 (4%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GPPG +G GD G G GP G +G G++G G PG GERG G GP GE G +G+ Sbjct: 951 GPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAP 1010 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G+ G +G G G PG GP+G+ PG+EG PG GPPG G G G+ G G Sbjct: 1011 GASGDRGPPGPVGPPGLTGPAGE------PGREGSPGADGPPGRDGAAGVKGDRGETGAV 1064 Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSG 587 G PG PG PG PGP GP G G G Sbjct: 1065 GAPGAPGPPGSPGPAGPTGKQGDRG 1089 Score = 98.2 bits (243), Expect = 2e-20 Identities = 60/150 (40%), Positives = 66/150 (44%), Gaps = 28/150 (18%) Query: 477 PPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGS----RGSPGKPGPQGPSGDPGPPGPP 532 P P GE PI P G G KG +G G G G PGPQGP+G+ GP G Sbjct: 78 PEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDR 137 Query: 533 GKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPG----------------------- 569 G +G G GP G G GT G PG PGP G PG PG Sbjct: 138 GDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLG 197 Query: 570 -VPGMPGPKGPPGPPGPSGAVVPLALQNEP 598 + G GP GP GPPGP+GA P Q P Sbjct: 198 VMQGPMGPMGPRGPPGPAGAPGPQGFQGNP 227 Score = 97.1 bits (240), Expect = 5e-20 Identities = 47/90 (52%), Positives = 53/90 (58%), Gaps = 3/90 (3%) Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGE 495 + FT LQG PGP GP GD+G+ GP GP+ G +G G GP G G G GP GPPG Sbjct: 1133 RGFTGLQGLPGPPGPSGDQGASGPAGPS---GPRGPPGPVGPSGKDGANGIPGPIGPPGP 1189 Query: 496 RGGKGSKGSQGPKGSRGSPGKPGPQGPSGD 525 RG G G GP G+ G PG PGP GP D Sbjct: 1190 RGRSGETGPAGPPGNPGPPGPPGPPGPGID 1219 Score = 38.9 bits (89), Expect = 0.017 Identities = 21/55 (38%), Positives = 26/55 (47%), Gaps = 4/55 (7%) Query: 554 GEPGVPGPRGLPG----LPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPED 604 G+PG G +G PG + G G PGP+GP G GP G + P P D Sbjct: 98 GQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRD 152 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 168 bits (425), Expect = 2e-41 Identities = 78/148 (52%), Positives = 92/148 (62%), Gaps = 3/148 (2%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GPPGP G G G+ G PG G +G+ G+KG+ G PGP G G GP GP G G KG++ Sbjct: 759 GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 818 Query: 503 GSQGPKGSRGSPG---KPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559 G+QGP G+ G PG + GP G +G+PGPPGPPG G GP+G G G G GEPG+ Sbjct: 819 GAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQ 878 Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 GP G PG G PG GP G GPPGP G Sbjct: 879 GPAGPPGEKGEPGDDGPSGAEGPPGPQG 906 Score = 163 bits (413), Expect = 5e-40 Identities = 88/175 (50%), Positives = 97/175 (55%), Gaps = 16/175 (9%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKG---EKGEPGPPGPAGERGPIGPAGPPGERGGK 499 GPPGP G G++G GPPGP G+ G +G E+GE GPPGPAG AGPPG G Sbjct: 723 GPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGF------AGPPGADGQP 776 Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP---PGKEGLPGPQGPPGFQGLQGTVGEP 556 G+KG QG G +G G PGPQGPSG PGP GP G +G G QGPPG G G G Sbjct: 777 GAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRV 836 Query: 557 GVPGPRGLPGLPGVP---GMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 G PG G PG PG P G GPKG G GP G LQ P P + G P Sbjct: 837 GPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQG-PAGPPGEKGEP 890 Score = 163 bits (412), Expect = 6e-40 Identities = 82/159 (51%), Positives = 93/159 (58%), Gaps = 12/159 (7%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 QGP G GP+G RG+QGPPG T G G G GPPG G GP GP GP G+ G KG+ Sbjct: 806 QGPTGVTGPKGARGAQGPPGAT---GFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA 862 Query: 502 KGSQGPKGSRGSPGKPGPQGP---SGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGE--- 555 +G GP G G PG GP GP G+PG GP G EG PGPQG G +G+ G G+ Sbjct: 863 RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGE 922 Query: 556 ---PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 PG+PGP G PG G PG G +GPPGP GP G P Sbjct: 923 RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGP 961 Score = 161 bits (408), Expect = 2e-39 Identities = 83/165 (50%), Positives = 92/165 (55%), Gaps = 9/165 (5%) Query: 443 GPPGPRGPRGDRGSQGPPGP---TGNKGQKGEKGEPGPPG------PAGERGPIGPAGPP 493 GPPGP+G RG G G PGP G G+ GEKG PG PG GE G GP GP Sbjct: 519 GPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPA 578 Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553 G G +G +G+ GP G +G PG PGP G G PG G PG+ G PG GP G +G G Sbjct: 579 GPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGER 638 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598 G PG G +G GLPG PG GPKG GP GP GA P LQ P Sbjct: 639 GSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMP 683 Score = 160 bits (405), Expect = 4e-39 Identities = 79/160 (49%), Positives = 95/160 (59%), Gaps = 15/160 (9%) Query: 443 GPPGPRGPRGDRGSQG------------PPGPTGNKGQKGEKGEPGPPGPAGERGPIGPA 490 GPPGP GP G+RG QG PPGP G G+ G++G PG G G GP G Sbjct: 573 GPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGER 632 Query: 491 GPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPG---PPGKEGLPGPQGPPGFQ 547 G PGERG G++G QGP+G G+PG GP+G SG GPPG PPG +G+PG +G G Sbjct: 633 GFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIA 692 Query: 548 GLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G +G G+ G GP G PG G G+ GP GPPGP G +G Sbjct: 693 GPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANG 732 Score = 159 bits (403), Expect = 7e-39 Identities = 84/174 (48%), Positives = 93/174 (53%), Gaps = 15/174 (8%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PGP GPRG G +G GP G G +G G+PGP GP G P+GPAG PG G G+K Sbjct: 249 GSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPG---PVGPAGGPGFPGAPGAK 305 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT---VGEPGVP 559 G GP G+RG G GP+G G PG PGP G G PG G PG +G G G PG P Sbjct: 306 GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP 365 Query: 560 GPRGLPGLPGVPGMPGPKGPPGPP---------GPSGAVVPLALQNEPTPAPED 604 GPRG PG G G GPKG G P GP G P Q P PA E+ Sbjct: 366 GPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEE 419 Score = 157 bits (398), Expect = 3e-38 Identities = 86/210 (40%), Positives = 105/210 (50%), Gaps = 37/210 (17%) Query: 435 IKNFTILQGPPGPRGP---------RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG 485 IK+ +GPPGP+GP RGD+G +G PGP G G+ G G PGPPGP G G Sbjct: 43 IKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPG 102 Query: 486 P---------------------------IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPG 518 P GP GP G RG G G+ GP+G +G+PG+PG Sbjct: 103 PPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG 162 Query: 519 PQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKG 578 G SG GP GPPG G PG G G G G G PG G RG PG PG+PG+ G +G Sbjct: 163 EPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRG 222 Query: 579 PPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 PG G G ++ E + +P +NG P Sbjct: 223 YPGLDGAKGEAGAPGVKGE-SGSPGENGSP 251 Score = 157 bits (398), Expect = 3e-38 Identities = 86/193 (44%), Positives = 102/193 (52%), Gaps = 36/193 (18%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQ------KGE------KGEPGPPGPAGERGPIGP 489 +GPPGP+G RG G+ G PG G++G KGE KGE G PG G GP+GP Sbjct: 197 RGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP 256 Query: 490 AGPPGERGGKGSKGSQGPKGSRGSPGK---PGPQGPSGDPGPPGPPGKEGLPGPQGPPGF 546 G PGERG G G+ G +G+ G PG PGP GP+G PG PG PG +G GP G G Sbjct: 257 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 316 Query: 547 QGLQGTVGEPGVP---------------------GPRGLPGLPGVPGMPGPKGPPGPPGP 585 +G QG GEPG P G G PG+ G PG PGP+GPPGP G Sbjct: 317 EGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGA 376 Query: 586 SGAVVPLALQNEP 598 +G + P EP Sbjct: 377 TGPLGPKGQTGEP 389 Score = 157 bits (396), Expect = 4e-38 Identities = 87/182 (47%), Positives = 99/182 (54%), Gaps = 36/182 (19%) Query: 442 QGPPGPRG---PRGDRGSQGPPGPTGNKGQKGEKGEPGP------PGPAGERGP------ 486 +GPPGP+G P G +G G PG G KG++G KGEPGP PGPAGE G Sbjct: 368 RGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGE 427 Query: 487 ---IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGP------PGPPGKEGL 537 +GP GPPGERG G++G G G G G PG +GPSG GP PG PG+ GL Sbjct: 428 PGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGL 487 Query: 538 P------------GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGP 585 P GPQG G G G G PG PGP+G G PGV G PGPKG G PG Sbjct: 488 PGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGK 547 Query: 586 SG 587 +G Sbjct: 548 AG 549 Score = 155 bits (393), Expect = 1e-37 Identities = 89/202 (44%), Positives = 102/202 (50%), Gaps = 35/202 (17%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG------------PPGPAGERGPIGP 489 QG PGP G G RG++G PG G G GE+G PG P G GERGP G Sbjct: 410 QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGL 469 Query: 490 AGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPG---- 545 AGP G G G G G G+RG G+PG GP G GP G PG++G PGP GP G Sbjct: 470 AGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ 529 Query: 546 -----FQGLQGTVGEPGVPGPRGLPGLPGVPGMP------GPKGPPGPPGPS------GA 588 F G +G GEPG G +GLPG PG+ G+P G GPPGP GP+ GA Sbjct: 530 PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 589 Query: 589 VVPLALQNEPTP--APEDNGCP 608 P Q P P P + G P Sbjct: 590 PGPSGFQGLPGPPGPPGEGGKP 611 Score = 155 bits (393), Expect = 1e-37 Identities = 84/175 (48%), Positives = 96/175 (54%), Gaps = 7/175 (4%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG---PIGPAGPPGERGG 498 QGPPG +G G+RG+ G GP G++G GEKG G PG G RG PIGP GP G G Sbjct: 674 QGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGE 733 Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPG---PPGKEGLPGPQGPPGFQGLQGTVGE 555 KG G GP GS G+ G PG +G +G PGP G PPG +G PG +G G G +G G Sbjct: 734 KGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGA 793 Query: 556 PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAV-VPLALQNEPTPAPEDNGCPP 609 PG GP G PG G G+ GPKG G GP GA P A P N PP Sbjct: 794 PGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPP 848 Score = 155 bits (392), Expect = 1e-37 Identities = 77/157 (49%), Positives = 87/157 (55%), Gaps = 6/157 (3%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PG GP G G GP G G++G+ G +G GP GPAG RG GP GP G++G G Sbjct: 996 GAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEP 1055 Query: 503 GSQGPKGSRGS------PGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G +G KG RG PG PGP G G GP GP G G PGP GP G G G G Sbjct: 1056 GERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPI 1115 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLA 593 G PGPRG G G G PG GPPGPPGP G + ++ Sbjct: 1116 GPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMS 1152 Score = 155 bits (391), Expect = 2e-37 Identities = 83/170 (48%), Positives = 91/170 (53%), Gaps = 7/170 (4%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +GP G G G RG GP GP G G GEKGE GPPGPAG G G G GE G G Sbjct: 704 KGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP 763 Query: 502 KGSQGPKGSRGSPGKPGPQGPSG---DPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV 558 G GP G+ G PG G QG +G D G PGP G G PGPQGP G G +G G G Sbjct: 764 AGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP 823 Query: 559 PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 PG G PG G G PG G PGPPGP G + ++ P A D+G P Sbjct: 824 PGATGFPGAAGRVGPPGSNGNPGPPGPPGP----SGKDGPKGARGDSGPP 869 Score = 155 bits (391), Expect = 2e-37 Identities = 85/181 (46%), Positives = 95/181 (52%), Gaps = 36/181 (19%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGER---GGK 499 G GP G G+ G GPPGP+G G KG +G+ GPPG AGE G GPAGPPGE+ G Sbjct: 834 GRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDD 893 Query: 500 GSKGSQGP------------------KGSRGSPGKPGPQ---------GPSGDPGPPGPP 532 G G++GP +G RG PG PGP G SGD GPPGP Sbjct: 894 GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPV 953 Query: 533 GKEGLPGPQGPPGFQGLQGTVGEP------GVPGPRGLPGLPGVPGMPGPKGPPGPPGPS 586 G GL GP G PG +G G G P GV G RG G G PG PGP G PGP GP+ Sbjct: 954 GPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPT 1013 Query: 587 G 587 G Sbjct: 1014 G 1014 Score = 154 bits (390), Expect = 2e-37 Identities = 83/181 (45%), Positives = 93/181 (51%), Gaps = 21/181 (11%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE------PGPPGPAGERGPIGPAGPPG 494 L GP G G G G+ GPPG G G KG++GE PG PGP G GP GP G G Sbjct: 958 LTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1017 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGK------------EGLPGPQG 542 +RG G++G GP G G+ G GPQGP GD G G PG+ +GLPGP G Sbjct: 1018 DRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPG 1077 Query: 543 PPGFQGLQGTVGEPGV---PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPT 599 P G QG G G G PGP G G G G+PGP GPPGP G SG P P Sbjct: 1078 PSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPG 1137 Query: 600 P 600 P Sbjct: 1138 P 1138 Score = 151 bits (381), Expect = 2e-36 Identities = 78/178 (43%), Positives = 93/178 (52%), Gaps = 18/178 (10%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 + GP G RG G++G +G PG G +G G G PGP G GE+G +GP GP G G +G Sbjct: 691 IAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARG 750 Query: 501 SKGSQ------------GPKGSRGSPGKPGPQGPS---GDPGPPGPPGKEGLPGPQGPPG 545 + G + GP G+ G PG G QG + GD G PGP G G PGPQGP G Sbjct: 751 APGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTG 810 Query: 546 FQGLQGTVGEPGVPGPRGLPGLP---GVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP 600 G +G G G PG G PG G PG G GPPGPPGPSG P + + P Sbjct: 811 VTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGP 868 Score = 150 bits (378), Expect = 5e-36 Identities = 80/169 (47%), Positives = 89/169 (52%), Gaps = 24/169 (14%) Query: 440 ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499 ++QGP GP GPRG G G PGP G +G GE GEPG GP G RGP GPPG+ G Sbjct: 129 VMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGP---PGPPGKPGDD 185 Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP------PGKEGLPGPQGPPGFQGLQGTV 553 G G G G RG PG G +G G PG PG PG +G G G PG +G G+ Sbjct: 186 GEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSP 245 Query: 554 GEPGVPGPRGLPGLPGV---------------PGMPGPKGPPGPPGPSG 587 GE G PGP G GLPG G PGP GPPGP GP+G Sbjct: 246 GENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAG 294 Score = 149 bits (377), Expect = 7e-36 Identities = 80/176 (45%), Positives = 94/176 (53%), Gaps = 10/176 (5%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +GP G +GPRG+ G+ G PGP G G G G PG G AG G G G PG RG G Sbjct: 314 RGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGP 373 Query: 502 KGSQGPKGSRGSPGKP------GPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGE 555 +G+ GP G +G G+P G QGP G+PGP GP G G G +G G +G G VG Sbjct: 374 QGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGP 433 Query: 556 PGVPGPRGLP---GLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 G PG RG P G PG G+ GPKG PG GPSG P +P P + G P Sbjct: 434 IGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDP-GRPGEPGLP 488 Score = 148 bits (373), Expect = 2e-35 Identities = 79/169 (46%), Positives = 96/169 (56%), Gaps = 16/169 (9%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PGPRGP G +G+ GP GP KG+ GEPG G GE+GP G GP G +G G Sbjct: 363 GFPGPRGPPGPQGATGPLGP------KGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA 416 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGP---PGKEGLPGPQGPPGFQGLQGTVGEPGVP 559 G +G +G+RG PG GP GP G+ G PG PG++GL GP+G PG +G G G G Sbjct: 417 GEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGAN 476 Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 G G PG PG+PG G G PG GP G V P+ AP ++G P Sbjct: 477 GDPGRPGEPGLPGARGLTGRPGDAGPQGKV-------GPSGAPGEDGRP 518 Score = 147 bits (371), Expect = 3e-35 Identities = 77/172 (44%), Positives = 92/172 (53%), Gaps = 7/172 (4%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GP G GP G G+QGPPG G G++G G GP G G+ G GP G PG+ GG+G Sbjct: 660 GPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLT 719 Query: 503 GS---QGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559 G GP G+ G G+ GP GP+G G G PG+ G GP GP GF G G G+PG Sbjct: 720 GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAK 779 Query: 560 GPRGLPGLPGVPGMPGPKGP---PGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 G +G G G G PGP+GP PGP GP+G P + P P G P Sbjct: 780 GEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP-PGATGFP 830 Score = 146 bits (369), Expect = 6e-35 Identities = 79/175 (45%), Positives = 91/175 (52%), Gaps = 8/175 (4%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 QG PG G RG G GPPG TG G+ G +G PG GP G G G G GE G G+ Sbjct: 938 QGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGA 997 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPG------PPGPPGKEGLPGPQGPPGFQGLQGTVGE 555 G+ GP GS G G G QG G+ G P GP G G+ GPQGP G +G G GE Sbjct: 998 PGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGE 1057 Query: 556 PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPED--NGCP 608 G+ G RG GL G+PG PGP G G GP+G P P+ +D NG P Sbjct: 1058 RGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIP 1112 Score = 146 bits (368), Expect = 8e-35 Identities = 78/162 (48%), Positives = 86/162 (53%), Gaps = 9/162 (5%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PG RG G G GP G G G GE G PGPPGP G RG G G PG +G G Sbjct: 486 GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEP 545 Query: 503 GSQGPKGS------RGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G G KG RG PGK G G +G PGP GP G+ G G GP GFQGL G G P Sbjct: 546 GKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPP 605 Query: 557 GV---PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQ 595 G PG +G+PG G PG+ GP+G G PG G+ LQ Sbjct: 606 GEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQ 647 Score = 145 bits (365), Expect = 2e-34 Identities = 73/148 (49%), Positives = 86/148 (58%), Gaps = 3/148 (2%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PG GPRG+RG G G G +G +G +G PG PG G +G GPAGPPG +G G + Sbjct: 621 GAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQ 680 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKE---GLPGPQGPPGFQGLQGTVGEPGVP 559 G G +G+ G G G +G G+ GP G PGK+ GL GP GPPG G G GE G P Sbjct: 681 GMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPP 740 Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 GP G G G PG G GPPGP G +G Sbjct: 741 GPAGSAGARGAPGERGETGPPGPAGFAG 768 Score = 144 bits (363), Expect = 3e-34 Identities = 74/151 (49%), Positives = 85/151 (56%), Gaps = 6/151 (3%) Query: 443 GPPGPRGPRGDRGSQGPPG------PTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGER 496 GPPGP GP G G G PG PTG +G +G +G G PG G GP G +G PG Sbjct: 285 GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTD 344 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G G+KGS G G G+PG PGP+GP G G GP G +G G G GF+G QG GEP Sbjct: 345 GIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 404 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G GP+G PG G G G +G PG GP G Sbjct: 405 GPAGPQGAPGPAGEEGKRGARGEPGGVGPIG 435 Score = 144 bits (362), Expect = 4e-34 Identities = 80/175 (45%), Positives = 86/175 (49%), Gaps = 46/175 (26%) Query: 460 PGPTGNKGQKGE-KGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPG 518 PGP G KG+ G+ K GP GP G +GP G GP G+RG KG KG+ GP+G G PG PG Sbjct: 31 PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPG 90 Query: 519 PQGPSGDPGPPGPPG---------------------------------KEGLPGPQGPPG 545 GP G PGPPGPPG G PGP G PG Sbjct: 91 NPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPG 150 Query: 546 FQGLQGTVGEPGVP------GPRGLPGLPGVP------GMPGPKGPPGPPGPSGA 588 QG QG GEPG P GPRG PG PG P G PG G GPPGP GA Sbjct: 151 PQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGA 205 Score = 143 bits (361), Expect = 5e-34 Identities = 81/174 (46%), Positives = 89/174 (51%), Gaps = 24/174 (13%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG--- 498 +G PG RG G +G QGP G G G G KG GP GP G +GP G G PGERG Sbjct: 632 RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 691 Query: 499 ---KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL------PGPQGPPGFQGL 549 KG +G G KG G+PGK G +G +G GPPGP G G PGP G G +G Sbjct: 692 AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA 751 Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPK------------GPPGPPGPSGAVVP 591 G GE G PGP G G PG G PG K G PGP GPSGA P Sbjct: 752 PGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGP 805 Score = 137 bits (345), Expect = 4e-32 Identities = 69/145 (47%), Positives = 81/145 (55%), Gaps = 6/145 (4%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GPPG +G GD G G GP G +G G++G G PG GERG G GP GE G +G+ Sbjct: 882 GPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAP 941 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G+ G +G G G PG GP+G+ PG+EG PG GPPG G G G+ G G Sbjct: 942 GASGDRGPPGPVGPPGLTGPAGE------PGREGSPGADGPPGRDGAAGVKGDRGETGAV 995 Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSG 587 G PG PG PG PGP GP G G G Sbjct: 996 GAPGAPGPPGSPGPAGPTGKQGDRG 1020 Score = 125 bits (314), Expect = 1e-28 Identities = 66/151 (43%), Positives = 75/151 (49%), Gaps = 37/151 (24%) Query: 474 EPGPPGPAGE----------------RGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKP 517 +PGP G GE +GP G GP G+RG KG KG+ GP+G G PG P Sbjct: 30 QPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTP 89 Query: 518 GPQGPSGDPGPPGPPGKEG---------------------LPGPQGPPGFQGLQGTVGEP 556 G GP G PGPPGPPG G + GP GP G +G G G P Sbjct: 90 GNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAP 149 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G G +G PG PG PG+ GP GP GPPGP G Sbjct: 150 GPQGFQGNPGEPGEPGVSGPMGPRGPPGPPG 180 Score = 97.1 bits (240), Expect = 5e-20 Identities = 47/90 (52%), Positives = 53/90 (58%), Gaps = 3/90 (3%) Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGE 495 + FT LQG PGP GP GD+G+ GP GP+ G +G G GP G G G GP GPPG Sbjct: 1064 RGFTGLQGLPGPPGPSGDQGASGPAGPS---GPRGPPGPVGPSGKDGANGIPGPIGPPGP 1120 Query: 496 RGGKGSKGSQGPKGSRGSPGKPGPQGPSGD 525 RG G G GP G+ G PG PGP GP D Sbjct: 1121 RGRSGETGPAGPPGNPGPPGPPGPPGPGID 1150 Score = 37.4 bits (85), Expect = 0.051 Identities = 21/56 (37%), Positives = 26/56 (46%), Gaps = 4/56 (7%) Query: 553 VGEPGVPGPRGLPG----LPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPED 604 V +PG G +G PG + G G PGP+GP G GP G + P P D Sbjct: 28 VRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRD 83 >gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo sapiens] Length = 1424 Score = 166 bits (421), Expect = 6e-41 Identities = 87/173 (50%), Positives = 104/173 (60%), Gaps = 16/173 (9%) Query: 441 LQGPPGPRGPRGDRGS---QGPPGPTGN---KGQKGEKGEPGPPGPAGERGPIGPAGPPG 494 L+G PG +G G G+ +G PGP G G+KG++G PG PG G GP GPAGPPG Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD-------PGPPGPPGKEGLPGPQGPPGFQ 547 G +G G QG +G G+PG PG GP G+ PGPPGPPG G PGPQGPPG Sbjct: 618 Y-GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIP 676 Query: 548 GLQGTVGEPGVPGPRGLPGLPGV--PGMPGPKGPPGPPGPSGAVVPLALQNEP 598 G G G+PG+PGP G PG+PG+ PG PGPKG G PG G++ EP Sbjct: 677 GSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEP 729 Score = 149 bits (376), Expect = 9e-36 Identities = 87/209 (41%), Positives = 98/209 (46%), Gaps = 42/209 (20%) Query: 435 IKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG------ 488 +K L GP GP GPRGD GS G PG G +G G G G PG G+RG +G Sbjct: 980 LKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAG 1039 Query: 489 -----------------------PAGPPGERGGKGSKGSQGPKGSRGSPGKPG---PQGP 522 GPPG G G G G KG G PG PG P GP Sbjct: 1040 RPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGP 1099 Query: 523 SGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGP------ 576 G PG PG PG G PGP G GF+G++G +G PG+ GP PGLPG PG PGP Sbjct: 1100 EGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGP---PGLPGFPGSPGPMGIRGD 1156 Query: 577 KGPPGPPGPSGAVVPLALQNEPTPAPEDN 605 +G G PGP+G L P P P N Sbjct: 1157 QGRDGIPGPAGEKGETGLLRAP-PGPRGN 1184 Score = 145 bits (367), Expect = 1e-34 Identities = 98/222 (44%), Positives = 109/222 (49%), Gaps = 52/222 (23%) Query: 440 ILQGPPGPRG------PRGDRGSQGPPGPTGNKGQKGEKGEPGP------PGPAGERGPI 487 +L+ PPGPRG +GDRG+ G PG G KG G+ G GP PGP G G I Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233 Query: 488 GPA-----GPPGERGGKGSKGSQGP--------KGSRGSPGKPGPQGP---SGDPGPPG- 530 P GPPG RG G+ G GP KG +GS G PGP+GP +GD GPPG Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293 Query: 531 --PPGKEGLPGPQGPPGFQGLQGTVGEPG---------VPGPRGLPGLPGVPGMPGP--- 576 PG GLPGP+G PGFQG G GE G PGP G G PGV G PG Sbjct: 1294 LGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKI 1353 Query: 577 ---KGPPGPPGPSGAVVPLALQNEP-TPAPEDN--GCPPHWK 612 G PGPPG G +Q EP P P N C P K Sbjct: 1354 ISLPGSPGPPGTPGEP---GMQGEPGPPGPPGNLGPCGPRGK 1392 Score = 145 bits (367), Expect = 1e-34 Identities = 85/187 (45%), Positives = 93/187 (49%), Gaps = 20/187 (10%) Query: 432 GQLIKNFTILQGPPGPRGPRGDRGSQGPPGP--TGNKGQKGEKGEPGPPGPAGERGPIGP 489 G +I T +GPPG RG G G GPPG G KG KG G PGP GP G G +GP Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP 1290 Query: 490 AGP---------PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG---- 536 G PG RG G +G G KG +G+PG G GP G GP GPPG G Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGT 1350 Query: 537 -----LPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 LPG GPPG G G GEPG PGP G G G G PG G PG PGP+G Sbjct: 1351 LKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGN 1410 Query: 592 LALQNEP 598 + EP Sbjct: 1411 KGSKGEP 1417 Score = 144 bits (363), Expect = 3e-34 Identities = 81/158 (51%), Positives = 91/158 (57%), Gaps = 9/158 (5%) Query: 439 TILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498 T + GPPGP GP G G QGPPG G+ G+ G+ G PGP G G G IG GPPG Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG-IGFPGPPGP--- 707 Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG--LPGPQGPPGFQGLQGTVGEP 556 KG +G G KGS G PGK G G G PG PG G+ +PG G PGF G +G GE Sbjct: 708 KGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767 Query: 557 GVPGPRGLPGLPGVPG---MPGPKGPPGPPGPSGAVVP 591 G G GLPGLPG PG + GP+G PG PGP G P Sbjct: 768 GEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGP 805 Score = 143 bits (361), Expect = 5e-34 Identities = 81/195 (41%), Positives = 94/195 (48%), Gaps = 35/195 (17%) Query: 443 GPPGPRGPRGDRGSQGPPG--------PTGNKGQKGEKGEPGPPGPAGERGP--IGPAGP 492 G GPRGP G G GPPG TGN+G G +G PG PGP G G IG G Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGD 1269 Query: 493 PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552 G G G KG G G G PG+ G G G PGP G PG +G PG +G G G G+ Sbjct: 1270 KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS 1329 Query: 553 VGEPGVPGPRGLPGL------------------PGVPGMPGPKGPPGPPGPSGAVVPLAL 594 +G PG GP+G PG+ PG PG PG +G PGPPGP G + P Sbjct: 1330 IGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGP 1389 Query: 595 QNEP-------TPAP 602 + +P TP P Sbjct: 1390 RGKPGKDGKPGTPGP 1404 Score = 141 bits (355), Expect = 2e-33 Identities = 80/171 (46%), Positives = 92/171 (53%), Gaps = 26/171 (15%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQ------KGEKGEPGPPGPA---------GERGPI 487 GPPGP G G G +G PG G KGQ KGE+G+ G PGP+ GE G Sbjct: 901 GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLK 960 Query: 488 GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD---PGPPGPPGKEGLPGPQGPP 544 G AG PGE+G +G G G KG +G PG GP GP GD G PG PG G+PG G Sbjct: 961 GFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNM 1020 Query: 545 GFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGP--------PGPPGPSG 587 G G +G G G PG G PGLPG+ G+ G KG PGPPGP+G Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071 Score = 139 bits (351), Expect = 7e-33 Identities = 82/187 (43%), Positives = 93/187 (49%), Gaps = 24/187 (12%) Query: 442 QGPPGPRGPRGDRGSQGP---------------PGPTGNKGQKGEKGEPGPPGPAGERGP 486 +G PG +G +GD+G+ GP G GN G+KG +G PG PG G +G Sbjct: 927 RGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGL 986 Query: 487 IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF 546 GPAGPPG RG GS G+ G G RG PG G G G G G G G G G PG Sbjct: 987 PGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGI 1046 Query: 547 QGLQGTVGEPGV-----PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601 GLQG GEPG PGP G G PG+PG G KG G PGP G + P P A Sbjct: 1047 HGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAG----PEGA 1102 Query: 602 PEDNGCP 608 P G P Sbjct: 1103 PGSPGSP 1109 Score = 139 bits (350), Expect = 9e-33 Identities = 82/177 (46%), Positives = 94/177 (53%), Gaps = 21/177 (11%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG------PIGPAGP--PG 494 G PGP GP+GD+G G G G G+ GE G PG PG G +G P GP P PG Sbjct: 700 GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPG------PQGPSGDPGPP---GPPGK--EGLPGPQGP 543 ERG G G G G G PG PG P+G G PGPP GPPG+ EG G QG Sbjct: 760 ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819 Query: 544 PGFQGLQGTVGEPGVPGPRGLPGLPGV--PGMPGPKGPPGPPGPSGAVVPLALQNEP 598 PG GL+G G G GP+G PG+PG+ G PG G PG PG G + PL + P Sbjct: 820 PGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876 Score = 139 bits (349), Expect = 1e-32 Identities = 78/174 (44%), Positives = 94/174 (54%), Gaps = 13/174 (7%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +G PG G +G G G PG G++G KG +G PG G G +G G GPPG RG Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEY 346 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP-----QGPPGFQGLQGTVGEP 556 + KG G+PG PGP+G G GP GPPG G PG +G PG+ GL+G+ GE Sbjct: 347 YDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGER 406 Query: 557 GVPG--PRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 G PG G PG PG G PG G PGPPGP G +V + P P D+G P Sbjct: 407 GRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIV---FRKGP---PGDHGLP 454 Score = 138 bits (347), Expect = 2e-32 Identities = 93/232 (40%), Positives = 109/232 (46%), Gaps = 68/232 (29%) Query: 441 LQGPPGP---------RGPRGDRGSQGPPGPTGNKGQ---------------------KG 470 LQG PG G +G+RG G G G KGQ KG Sbjct: 295 LQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG 354 Query: 471 EKGEPGPPGPAGERGPIGPAGPPGERGGKGSK-----------GSQGPKGSRGSPGK--- 516 ++G PGPPGP G RGP GP+GPPG G GS G +G KG RG PGK Sbjct: 355 DEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAM 414 Query: 517 --PGPQGPSGDPGPPGPPGKEGLPGP----QGPPGFQGLQGTVGEPGVP---GPRGLPGL 567 PG G +G PG PG PG G PG +GPPG GL G +G PG+P GP+G PGL Sbjct: 415 GTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGL 474 Query: 568 -----------PGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 PG+PG+PG G G PG GA L+ P +P + G P Sbjct: 475 LCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA---GLKGSP-GSPGNTGLP 522 Score = 137 bits (345), Expect = 4e-32 Identities = 73/154 (47%), Positives = 86/154 (55%), Gaps = 9/154 (5%) Query: 443 GPPGPRGP---RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499 GPPG G G G+ GPPGP GN G G++G PG PG G+RG G G G++G Sbjct: 883 GPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNP 942 Query: 500 GSK------GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553 G G +G G +G G PG +G G PG PG G +GLPGP GPPG +G G+ Sbjct: 943 GPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGST 1002 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G PG PG RG+PG G GMPG KG G G G Sbjct: 1003 GNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036 Score = 135 bits (341), Expect = 1e-31 Identities = 78/180 (43%), Positives = 90/180 (50%), Gaps = 23/180 (12%) Query: 442 QGPPGPRGPRGD--------------RGSQGPPGPTGNKGQKGEKGEPGPPG---PAGER 484 QG G GP+GD GS G PG G G G++G PG PG P GE Sbjct: 829 QGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGED 888 Query: 485 GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQ--- 541 G IG G PG G G G+ G G RGSPG PG +G G PG G G +G PGP Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEIS 948 Query: 542 ---GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598 G G GL+G G PG G RG+PG+PG+ G+ G GP GPPGP G + EP Sbjct: 949 HVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEP 1008 Score = 135 bits (341), Expect = 1e-31 Identities = 91/228 (39%), Positives = 105/228 (46%), Gaps = 48/228 (21%) Query: 421 MEEMKLVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQ-----------GPPGPTGN---K 466 M M + SK + F G PG G G +G + GPPGPTG+ Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076 Query: 467 GQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGP------KGSRGSPGKPGPQ 520 G G+KGE G PGP G GP GP G PG G G G GP KG +G G PG + Sbjct: 1077 GDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIR 1136 Query: 521 GPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV----PGPRGLP---------GL 567 GP G PG PG PG G+ G QG G G G GE G+ PGPRG P G Sbjct: 1137 GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGA 1196 Query: 568 PGVPGMP---------GPKGP------PGPPGPSGAVVPLALQNEPTP 600 PG PG+P GP+GP PGPPG GA++P N P Sbjct: 1197 PGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPP 1244 Score = 133 bits (335), Expect = 5e-31 Identities = 84/215 (39%), Positives = 103/215 (47%), Gaps = 53/215 (24%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG- 500 +G PG +G G+ G +G G G G KG KG PGP GP G RG +G G PGE G +G Sbjct: 954 KGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGI 1013 Query: 501 -----------SKGSQGP------------------KGSRGSPG-----KPGPQGPSGDP 526 SKG +G +G +G PG +PGP GP+GDP Sbjct: 1014 PGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDP 1073 Query: 527 GPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLP------------GVPGMP 574 G PG GK+G G GPPG G G G PG PG GLPG P G+ G P Sbjct: 1074 GLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPP 1133 Query: 575 GPKGPPGPPGPSGAVVPLALQNE------PTPAPE 603 G +GPPG PG G+ P+ ++ + P PA E Sbjct: 1134 GIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE 1168 Score = 132 bits (332), Expect = 1e-30 Identities = 69/159 (43%), Positives = 81/159 (50%), Gaps = 20/159 (12%) Query: 446 GPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQ 505 G +G +G++G GPPG G KG G +G PGP GP G G G G G RG G G Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 506 GPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV------------ 553 G G G+PG GP G G PG G G++G PG G G+ G+ G Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162 Query: 554 --------GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPG 584 G+PG+PG G GLPG PG PGP GPPGPPG Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPG 201 Score = 129 bits (325), Expect = 8e-30 Identities = 72/154 (46%), Positives = 82/154 (53%), Gaps = 26/154 (16%) Query: 464 GNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPS 523 G KG+KGEKG PGPPG G++G GP G PG +G KG G G GS+G G G G S Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 524 GDPGPPGPPGKEG---------LPGPQGPPGFQGLQGTVGEPGVPGPRGLPGL------- 567 G PG PG PG G G +G GF GL GT+G PG+PG GL G Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162 Query: 568 ----------PGVPGMPGPKGPPGPPGPSGAVVP 591 PG+PG PGP+G PGPPG G V P Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP 196 Score = 129 bits (324), Expect = 1e-29 Identities = 82/194 (42%), Positives = 90/194 (46%), Gaps = 31/194 (15%) Query: 441 LQGPPGPRGPRGDRG-SQGPPGPTGNKGQKGEKGEPGPPGPAGERG-----------PIG 488 L G PGP GP GD +GPPG G G G G PG GP GE G P G Sbjct: 428 LPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPG 487 Query: 489 PAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPG-------PQ 541 G PG G KG G QG G +GSPG PG G G PG PG G GL G P+ Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPE 547 Query: 542 GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKG------------PPGPPGPSGAV 589 G G G G G+PG G G+PG PGV G+PGPKG PPG PG G+ Sbjct: 548 GQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSP 607 Query: 590 VPLALQNEPTPAPE 603 P P P+ Sbjct: 608 GPAGPAGPPGYGPQ 621 Score = 125 bits (315), Expect = 1e-28 Identities = 79/186 (42%), Positives = 88/186 (47%), Gaps = 34/186 (18%) Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQK------GEKGEPGPPGPAGERGPIGP 489 K FT +G PGP+GP +G G PG TG+KG + G G PG PG G GP G Sbjct: 63 KGFTGPEGLPGPQGP---KGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGL 119 Query: 490 AGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPP-----------GPPGKEGLP 538 G PG G KG +G G G+ G PG PG G G G P G PG G P Sbjct: 120 VGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAP 179 Query: 539 GPQGPPGFQGLQGTVGEPGVPGPRGLPG--------------LPGVPGMPGPKGPPGPPG 584 GPQG PG G G VG PG PG G PG + G G G KG GPPG Sbjct: 180 GPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPG 239 Query: 585 PSGAVV 590 P G V+ Sbjct: 240 PPGTVI 245 Score = 124 bits (312), Expect = 2e-28 Identities = 75/184 (40%), Positives = 89/184 (48%), Gaps = 39/184 (21%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGN--------KGQKGEKGEPGPPGPAGE-----RGPIGP 489 GPPGP G G G+ GP GP G+ KG++G KG GPPGP G GP Sbjct: 195 GPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNR 254 Query: 490 AGPPGERGGKGSKGSQGPKG-----------SRGSPGKPGPQGPSGDPGPPGPPGKEGL- 537 GE+G KG+ G GP G +G+PG PG QG G G PG PG EG+ Sbjct: 255 TDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVK 314 Query: 538 -----PGPQGPPGFQGLQGTVGEPGVPGP---------RGLPGLPGVPGMPGPKGPPGPP 583 PG G G +G +G +G PG GP +G G PG PG G +GP GP Sbjct: 315 GNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPS 374 Query: 584 GPSG 587 GP G Sbjct: 375 GPPG 378 Score = 124 bits (311), Expect = 3e-28 Identities = 77/176 (43%), Positives = 85/176 (48%), Gaps = 36/176 (20%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP-------IGPAGPP 493 ++G PG +G G +GS G PG TG G G G G PG GE+G +G G P Sbjct: 497 VKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDP 556 Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGPQGP------SGDPGPPGPPGKEGLPGPQGPPGFQ 547 G RG G KG G G+ G G PGP+G GD GPPG PG G PGP GP G Sbjct: 557 GLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPP 616 Query: 548 GLQGTVGEPGVPGPRGLPGLPGVPGMPGP----------------KGPPGPPGPSG 587 G G GEPG L G GVPG PGP GPPGPPGP G Sbjct: 617 GY-GPQGEPG------LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665 Score = 124 bits (310), Expect = 4e-28 Identities = 89/233 (38%), Positives = 99/233 (42%), Gaps = 67/233 (28%) Query: 443 GPPGP-------RGPRGDRGSQGPPGPTGNKGQKGEKGEPG-----------PPGPAGER 484 GPPGP +GP GD G G G G G G KGEPG PPG G Sbjct: 433 GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLP 492 Query: 485 GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPG----------PPGPPGK 534 G G G PG +G G KGS G G+ G PG PG G GDPG P G G Sbjct: 493 GLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGV 552 Query: 535 EGLPGPQGPPGFQGLQGTVGEPGV---PGPRGL------------PGLPGVPGMPGPKGP 579 G PG +G PG +GL G G PGV PGP+G PG PG PG PGP GP Sbjct: 553 PGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGP 612 Query: 580 -----------------------PGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609 PGPPG +G L++ + P P P PP Sbjct: 613 AGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSV-STPVPGPPGPPGPP 664 Score = 122 bits (306), Expect = 1e-27 Identities = 77/179 (43%), Positives = 90/179 (50%), Gaps = 34/179 (18%) Query: 443 GPPGPRGPRGDRGS------QGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPA------ 490 G PG RG G+ G G PG GN+G G +G+PG PGP GE+GP G Sbjct: 756 GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815 Query: 491 --GPPGERGGKGSKGSQGPKGSRGSPGKPGPQ-----GPSGDPGPPG------PPGKEGL 537 G PG G KG +G +G G +G PG PG G +G PG PG P G+ G Sbjct: 816 AQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGY 875 Query: 538 PGPQG---PPGFQGLQGTVGEPGV---PGPRGLPGLP---GVPGMPGPKGPPGPPGPSG 587 PG G PPG G+ G +G PG PGP G PG P G PG+PG KG G PG G Sbjct: 876 PGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKG 934 Score = 117 bits (292), Expect = 5e-26 Identities = 74/173 (42%), Positives = 82/173 (47%), Gaps = 36/173 (20%) Query: 451 RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGE---RGPIGPAGPPGERGGK--GSKGSQ 505 +GD G G PGP G G G G GPPGP G G +GP GP G G + G KG + Sbjct: 170 KGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGER 229 Query: 506 GPKGSRGSPGKPGP-----------------QGPSGDPGPPGPPGKEGLPGP-----QGP 543 G KG G PG PG +G G G PGPPG GLPG +G Sbjct: 230 GVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGA 289 Query: 544 PGFQGLQGTVGEPGVP---------GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 PG GLQG G+ GVP G RG PGL G G+ G KG GPPG G Sbjct: 290 PGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRG 342 Score = 115 bits (289), Expect = 1e-25 Identities = 80/211 (37%), Positives = 91/211 (43%), Gaps = 32/211 (15%) Query: 426 LVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG 485 L SK + I G PG G G+ G G G G G KGE+G PG PG G G Sbjct: 86 LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145 Query: 486 PIGPAGPPGERGGKG--------SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL 537 G AG G++G +KG G G+ G G PGP G G GPPGPPG G Sbjct: 146 IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205 Query: 538 PGPQGPPGFQGLQG--TVGEPGVPGPRGLPGLPGVPGM--------------------PG 575 PG GP G +G G +G G G +GL G PG PG G Sbjct: 206 PGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKG 265 Query: 576 PKGPPGPPGPSGAVVPLALQNEPTPAPEDNG 606 G PGPPGPSG +P AP D G Sbjct: 266 AMGEPGPPGPSG--LPGESYGSEKGAPGDPG 294 >gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo sapiens] Length = 1494 Score = 166 bits (421), Expect = 6e-41 Identities = 87/173 (50%), Positives = 104/173 (60%), Gaps = 16/173 (9%) Query: 441 LQGPPGPRGPRGDRGS---QGPPGPTGN---KGQKGEKGEPGPPGPAGERGPIGPAGPPG 494 L+G PG +G G G+ +G PGP G G+KG++G PG PG G GP GPAGPPG Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD-------PGPPGPPGKEGLPGPQGPPGFQ 547 G +G G QG +G G+PG PG GP G+ PGPPGPPG G PGPQGPPG Sbjct: 618 Y-GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIP 676 Query: 548 GLQGTVGEPGVPGPRGLPGLPGV--PGMPGPKGPPGPPGPSGAVVPLALQNEP 598 G G G+PG+PGP G PG+PG+ PG PGPKG G PG G++ EP Sbjct: 677 GSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEP 729 Score = 150 bits (380), Expect = 3e-36 Identities = 88/193 (45%), Positives = 96/193 (49%), Gaps = 20/193 (10%) Query: 432 GQLIKNFTILQGPPGPRGPRGDRGSQGPPGP--TGNKGQKGEKGEPGPPGPAGERGPIGP 489 G +I T +GPPG RG G G GPPG G KG KG G PGP GP G G +GP Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP 1290 Query: 490 AGP---------PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG---- 536 G PG RG G +G G KG +G+PG G GP G GP GPPG G Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGT 1350 Query: 537 -----LPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 LPG GPPG G G GEPG PGP G G G G PG G PG PGP+G Sbjct: 1351 LKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGN 1410 Query: 592 LALQNEPTPAPED 604 + EP PA D Sbjct: 1411 KGSKGEPGPAGSD 1423 Score = 149 bits (376), Expect = 9e-36 Identities = 87/209 (41%), Positives = 98/209 (46%), Gaps = 42/209 (20%) Query: 435 IKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG------ 488 +K L GP GP GPRGD GS G PG G +G G G G PG G+RG +G Sbjct: 980 LKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAG 1039 Query: 489 -----------------------PAGPPGERGGKGSKGSQGPKGSRGSPGKPG---PQGP 522 GPPG G G G G KG G PG PG P GP Sbjct: 1040 RPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGP 1099 Query: 523 SGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGP------ 576 G PG PG PG G PGP G GF+G++G +G PG+ GP PGLPG PG PGP Sbjct: 1100 EGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGP---PGLPGFPGSPGPMGIRGD 1156 Query: 577 KGPPGPPGPSGAVVPLALQNEPTPAPEDN 605 +G G PGP+G L P P P N Sbjct: 1157 QGRDGIPGPAGEKGETGLLRAP-PGPRGN 1184 Score = 145 bits (367), Expect = 1e-34 Identities = 98/222 (44%), Positives = 109/222 (49%), Gaps = 52/222 (23%) Query: 440 ILQGPPGPRG------PRGDRGSQGPPGPTGNKGQKGEKGEPGP------PGPAGERGPI 487 +L+ PPGPRG +GDRG+ G PG G KG G+ G GP PGP G G I Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233 Query: 488 GPA-----GPPGERGGKGSKGSQGP--------KGSRGSPGKPGPQGP---SGDPGPPG- 530 P GPPG RG G+ G GP KG +GS G PGP+GP +GD GPPG Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293 Query: 531 --PPGKEGLPGPQGPPGFQGLQGTVGEPG---------VPGPRGLPGLPGVPGMPGP--- 576 PG GLPGP+G PGFQG G GE G PGP G G PGV G PG Sbjct: 1294 LGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKI 1353 Query: 577 ---KGPPGPPGPSGAVVPLALQNEP-TPAPEDN--GCPPHWK 612 G PGPPG G +Q EP P P N C P K Sbjct: 1354 ISLPGSPGPPGTPGEP---GMQGEPGPPGPPGNLGPCGPRGK 1392 Score = 144 bits (363), Expect = 3e-34 Identities = 81/158 (51%), Positives = 91/158 (57%), Gaps = 9/158 (5%) Query: 439 TILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498 T + GPPGP GP G G QGPPG G+ G+ G+ G PGP G G G IG GPPG Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG-IGFPGPPGP--- 707 Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG--LPGPQGPPGFQGLQGTVGEP 556 KG +G G KGS G PGK G G G PG PG G+ +PG G PGF G +G GE Sbjct: 708 KGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767 Query: 557 GVPGPRGLPGLPGVPG---MPGPKGPPGPPGPSGAVVP 591 G G GLPGLPG PG + GP+G PG PGP G P Sbjct: 768 GEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGP 805 Score = 141 bits (355), Expect = 2e-33 Identities = 80/171 (46%), Positives = 92/171 (53%), Gaps = 26/171 (15%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQ------KGEKGEPGPPGPA---------GERGPI 487 GPPGP G G G +G PG G KGQ KGE+G+ G PGP+ GE G Sbjct: 901 GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLK 960 Query: 488 GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD---PGPPGPPGKEGLPGPQGPP 544 G AG PGE+G +G G G KG +G PG GP GP GD G PG PG G+PG G Sbjct: 961 GFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNM 1020 Query: 545 GFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGP--------PGPPGPSG 587 G G +G G G PG G PGLPG+ G+ G KG PGPPGP+G Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071 Score = 139 bits (351), Expect = 7e-33 Identities = 82/187 (43%), Positives = 93/187 (49%), Gaps = 24/187 (12%) Query: 442 QGPPGPRGPRGDRGSQGP---------------PGPTGNKGQKGEKGEPGPPGPAGERGP 486 +G PG +G +GD+G+ GP G GN G+KG +G PG PG G +G Sbjct: 927 RGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGL 986 Query: 487 IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF 546 GPAGPPG RG GS G+ G G RG PG G G G G G G G G G PG Sbjct: 987 PGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGI 1046 Query: 547 QGLQGTVGEPGV-----PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601 GLQG GEPG PGP G G PG+PG G KG G PGP G + P P A Sbjct: 1047 HGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAG----PEGA 1102 Query: 602 PEDNGCP 608 P G P Sbjct: 1103 PGSPGSP 1109 Score = 139 bits (350), Expect = 9e-33 Identities = 82/177 (46%), Positives = 94/177 (53%), Gaps = 21/177 (11%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG------PIGPAGP--PG 494 G PGP GP+GD+G G G G G+ GE G PG PG G +G P GP P PG Sbjct: 700 GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPG------PQGPSGDPGPP---GPPGK--EGLPGPQGP 543 ERG G G G G G PG PG P+G G PGPP GPPG+ EG G QG Sbjct: 760 ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819 Query: 544 PGFQGLQGTVGEPGVPGPRGLPGLPGV--PGMPGPKGPPGPPGPSGAVVPLALQNEP 598 PG GL+G G G GP+G PG+PG+ G PG G PG PG G + PL + P Sbjct: 820 PGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876 Score = 139 bits (349), Expect = 1e-32 Identities = 78/174 (44%), Positives = 94/174 (54%), Gaps = 13/174 (7%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +G PG G +G G G PG G++G KG +G PG G G +G G GPPG RG Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEY 346 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP-----QGPPGFQGLQGTVGEP 556 + KG G+PG PGP+G G GP GPPG G PG +G PG+ GL+G+ GE Sbjct: 347 YDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGER 406 Query: 557 GVPG--PRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 G PG G PG PG G PG G PGPPGP G +V + P P D+G P Sbjct: 407 GRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIV---FRKGP---PGDHGLP 454 Score = 138 bits (347), Expect = 2e-32 Identities = 93/232 (40%), Positives = 109/232 (46%), Gaps = 68/232 (29%) Query: 441 LQGPPGP---------RGPRGDRGSQGPPGPTGNKGQ---------------------KG 470 LQG PG G +G+RG G G G KGQ KG Sbjct: 295 LQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG 354 Query: 471 EKGEPGPPGPAGERGPIGPAGPPGERGGKGSK-----------GSQGPKGSRGSPGK--- 516 ++G PGPPGP G RGP GP+GPPG G GS G +G KG RG PGK Sbjct: 355 DEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAM 414 Query: 517 --PGPQGPSGDPGPPGPPGKEGLPGP----QGPPGFQGLQGTVGEPGVP---GPRGLPGL 567 PG G +G PG PG PG G PG +GPPG GL G +G PG+P GP+G PGL Sbjct: 415 GTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGL 474 Query: 568 -----------PGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 PG+PG+PG G G PG GA L+ P +P + G P Sbjct: 475 LCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA---GLKGSP-GSPGNTGLP 522 Score = 138 bits (347), Expect = 2e-32 Identities = 76/163 (46%), Positives = 81/163 (49%), Gaps = 24/163 (14%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQ------------------KGEKGEPGPPGPAGER 484 G PGP+GP G G GPPG G G KGEKG PG G G Sbjct: 1274 GHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPP 1333 Query: 485 GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPP 544 GPIGP GPPG RG G+ GS G PG PG G G+PGPPGPPG G GP+G P Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393 Query: 545 GFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G G+PG PGP G G G G PGP G G PG G Sbjct: 1394 GKD------GKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKG 1430 Score = 137 bits (345), Expect = 4e-32 Identities = 73/154 (47%), Positives = 86/154 (55%), Gaps = 9/154 (5%) Query: 443 GPPGPRGP---RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499 GPPG G G G+ GPPGP GN G G++G PG PG G+RG G G G++G Sbjct: 883 GPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNP 942 Query: 500 GSK------GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553 G G +G G +G G PG +G G PG PG G +GLPGP GPPG +G G+ Sbjct: 943 GPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGST 1002 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G PG PG RG+PG G GMPG KG G G G Sbjct: 1003 GNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036 Score = 135 bits (341), Expect = 1e-31 Identities = 78/180 (43%), Positives = 90/180 (50%), Gaps = 23/180 (12%) Query: 442 QGPPGPRGPRGD--------------RGSQGPPGPTGNKGQKGEKGEPGPPG---PAGER 484 QG G GP+GD GS G PG G G G++G PG PG P GE Sbjct: 829 QGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGED 888 Query: 485 GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQ--- 541 G IG G PG G G G+ G G RGSPG PG +G G PG G G +G PGP Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEIS 948 Query: 542 ---GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598 G G GL+G G PG G RG+PG+PG+ G+ G GP GPPGP G + EP Sbjct: 949 HVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEP 1008 Score = 135 bits (341), Expect = 1e-31 Identities = 91/228 (39%), Positives = 105/228 (46%), Gaps = 48/228 (21%) Query: 421 MEEMKLVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQ-----------GPPGPTGN---K 466 M M + SK + F G PG G G +G + GPPGPTG+ Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076 Query: 467 GQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGP------KGSRGSPGKPGPQ 520 G G+KGE G PGP G GP GP G PG G G G GP KG +G G PG + Sbjct: 1077 GDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIR 1136 Query: 521 GPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV----PGPRGLP---------GL 567 GP G PG PG PG G+ G QG G G G GE G+ PGPRG P G Sbjct: 1137 GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGA 1196 Query: 568 PGVPGMP---------GPKGP------PGPPGPSGAVVPLALQNEPTP 600 PG PG+P GP+GP PGPPG GA++P N P Sbjct: 1197 PGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPP 1244 Score = 135 bits (341), Expect = 1e-31 Identities = 80/177 (45%), Positives = 89/177 (50%), Gaps = 6/177 (3%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PG GPRGD G QG PG G KG G G GPPGP G +GP G G PG Sbjct: 1298 GTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLP 1357 Query: 503 GSQGPKGSRGSP---GKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559 GS GP G+ G P G+PGP GP G+ GP GP GK G G G PG G +G G G P Sbjct: 1358 GSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEP 1417 Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA-PEDNGCPPHWKNFT 615 GP G GLPG+ G G G P G V Q P+ PE G P + F+ Sbjct: 1418 GPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPE--GTVPLYSGFS 1472 Score = 133 bits (335), Expect = 5e-31 Identities = 84/215 (39%), Positives = 103/215 (47%), Gaps = 53/215 (24%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG- 500 +G PG +G G+ G +G G G G KG KG PGP GP G RG +G G PGE G +G Sbjct: 954 KGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGI 1013 Query: 501 -----------SKGSQGP------------------KGSRGSPG-----KPGPQGPSGDP 526 SKG +G +G +G PG +PGP GP+GDP Sbjct: 1014 PGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDP 1073 Query: 527 GPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLP------------GVPGMP 574 G PG GK+G G GPPG G G G PG PG GLPG P G+ G P Sbjct: 1074 GLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPP 1133 Query: 575 GPKGPPGPPGPSGAVVPLALQNE------PTPAPE 603 G +GPPG PG G+ P+ ++ + P PA E Sbjct: 1134 GIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE 1168 Score = 132 bits (332), Expect = 1e-30 Identities = 69/159 (43%), Positives = 81/159 (50%), Gaps = 20/159 (12%) Query: 446 GPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQ 505 G +G +G++G GPPG G KG G +G PGP GP G G G G G RG G G Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 506 GPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV------------ 553 G G G+PG GP G G PG G G++G PG G G+ G+ G Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162 Query: 554 --------GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPG 584 G+PG+PG G GLPG PG PGP GPPGPPG Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPG 201 Score = 129 bits (325), Expect = 8e-30 Identities = 72/154 (46%), Positives = 82/154 (53%), Gaps = 26/154 (16%) Query: 464 GNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPS 523 G KG+KGEKG PGPPG G++G GP G PG +G KG G G GS+G G G G S Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 524 GDPGPPGPPGK---------EGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGL------- 567 G PG PG PG G G +G GF GL GT+G PG+PG GL G Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162 Query: 568 ----------PGVPGMPGPKGPPGPPGPSGAVVP 591 PG+PG PGP+G PGPPG G V P Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP 196 Score = 129 bits (324), Expect = 1e-29 Identities = 82/194 (42%), Positives = 90/194 (46%), Gaps = 31/194 (15%) Query: 441 LQGPPGPRGPRGDRG-SQGPPGPTGNKGQKGEKGEPGPPGPAGERG-----------PIG 488 L G PGP GP GD +GPPG G G G G PG GP GE G P G Sbjct: 428 LPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPG 487 Query: 489 PAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPG-------PQ 541 G PG G KG G QG G +GSPG PG G G PG PG G GL G P+ Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPE 547 Query: 542 GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKG------------PPGPPGPSGAV 589 G G G G G+PG G G+PG PGV G+PGPKG PPG PG G+ Sbjct: 548 GQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSP 607 Query: 590 VPLALQNEPTPAPE 603 P P P+ Sbjct: 608 GPAGPAGPPGYGPQ 621 Score = 125 bits (315), Expect = 1e-28 Identities = 79/186 (42%), Positives = 88/186 (47%), Gaps = 34/186 (18%) Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQK------GEKGEPGPPGPAGERGPIGP 489 K FT +G PGP+GP +G G PG TG+KG + G G PG PG G GP G Sbjct: 63 KGFTGPEGLPGPQGP---KGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGL 119 Query: 490 AGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPP-----------GPPGKEGLP 538 G PG G KG +G G G+ G PG PG G G G P G PG G P Sbjct: 120 VGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAP 179 Query: 539 GPQGPPGFQGLQGTVGEPGVPGPRGLPG--------------LPGVPGMPGPKGPPGPPG 584 GPQG PG G G VG PG PG G PG + G G G KG GPPG Sbjct: 180 GPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPG 239 Query: 585 PSGAVV 590 P G V+ Sbjct: 240 PPGTVI 245 Score = 124 bits (312), Expect = 2e-28 Identities = 75/184 (40%), Positives = 89/184 (48%), Gaps = 39/184 (21%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGN--------KGQKGEKGEPGPPGPAGE-----RGPIGP 489 GPPGP G G G+ GP GP G+ KG++G KG GPPGP G GP Sbjct: 195 GPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNR 254 Query: 490 AGPPGERGGKGSKGSQGPKG-----------SRGSPGKPGPQGPSGDPGPPGPPGKEGL- 537 GE+G KG+ G GP G +G+PG PG QG G G PG PG EG+ Sbjct: 255 TDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVK 314 Query: 538 -----PGPQGPPGFQGLQGTVGEPGVPGP---------RGLPGLPGVPGMPGPKGPPGPP 583 PG G G +G +G +G PG GP +G G PG PG G +GP GP Sbjct: 315 GNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPS 374 Query: 584 GPSG 587 GP G Sbjct: 375 GPPG 378 Score = 124 bits (311), Expect = 3e-28 Identities = 77/176 (43%), Positives = 85/176 (48%), Gaps = 36/176 (20%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP-------IGPAGPP 493 ++G PG +G G +GS G PG TG G G G G PG GE+G +G G P Sbjct: 497 VKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDP 556 Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGPQGP------SGDPGPPGPPGKEGLPGPQGPPGFQ 547 G RG G KG G G+ G G PGP+G GD GPPG PG G PGP GP G Sbjct: 557 GLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPP 616 Query: 548 GLQGTVGEPGVPGPRGLPGLPGVPGMPGP----------------KGPPGPPGPSG 587 G G GEPG L G GVPG PGP GPPGPPGP G Sbjct: 617 GY-GPQGEPG------LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665 Score = 124 bits (310), Expect = 4e-28 Identities = 89/233 (38%), Positives = 99/233 (42%), Gaps = 67/233 (28%) Query: 443 GPPGP-------RGPRGDRGSQGPPGPTGNKGQKGEKGEPG-----------PPGPAGER 484 GPPGP +GP GD G G G G G G KGEPG PPG G Sbjct: 433 GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLP 492 Query: 485 GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPG----------PPGPPGK 534 G G G PG +G G KGS G G+ G PG PG G GDPG P G G Sbjct: 493 GLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGV 552 Query: 535 EGLPGPQGPPGFQGLQGTVGEPGV---PGPRGL------------PGLPGVPGMPGPKGP 579 G PG +G PG +GL G G PGV PGP+G PG PG PG PGP GP Sbjct: 553 PGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGP 612 Query: 580 -----------------------PGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609 PGPPG +G L++ + P P P PP Sbjct: 613 AGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSV-STPVPGPPGPPGPP 664 Score = 122 bits (306), Expect = 1e-27 Identities = 77/179 (43%), Positives = 90/179 (50%), Gaps = 34/179 (18%) Query: 443 GPPGPRGPRGDRGS------QGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPA------ 490 G PG RG G+ G G PG GN+G G +G+PG PGP GE+GP G Sbjct: 756 GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815 Query: 491 --GPPGERGGKGSKGSQGPKGSRGSPGKPGPQ-----GPSGDPGPPG------PPGKEGL 537 G PG G KG +G +G G +G PG PG G +G PG PG P G+ G Sbjct: 816 AQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGY 875 Query: 538 PGPQG---PPGFQGLQGTVGEPGV---PGPRGLPGLP---GVPGMPGPKGPPGPPGPSG 587 PG G PPG G+ G +G PG PGP G PG P G PG+PG KG G PG G Sbjct: 876 PGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKG 934 Score = 117 bits (292), Expect = 5e-26 Identities = 74/173 (42%), Positives = 82/173 (47%), Gaps = 36/173 (20%) Query: 451 RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGE---RGPIGPAGPPGERGGK--GSKGSQ 505 +GD G G PGP G G G G GPPGP G G +GP GP G G + G KG + Sbjct: 170 KGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGER 229 Query: 506 GPKGSRGSPGKPGP-----------------QGPSGDPGPPGPPGKEGLPGP-----QGP 543 G KG G PG PG +G G G PGPPG GLPG +G Sbjct: 230 GVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGA 289 Query: 544 PGFQGLQGTVGEPGVP---------GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 PG GLQG G+ GVP G RG PGL G G+ G KG GPPG G Sbjct: 290 PGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRG 342 Score = 115 bits (289), Expect = 1e-25 Identities = 80/211 (37%), Positives = 91/211 (43%), Gaps = 32/211 (15%) Query: 426 LVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG 485 L SK + I G PG G G+ G G G G G KGE+G PG PG G G Sbjct: 86 LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145 Query: 486 PIGPAGPPGERGGKG--------SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL 537 G AG G++G +KG G G+ G G PGP G G GPPGPPG G Sbjct: 146 IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205 Query: 538 PGPQGPPGFQGLQG--TVGEPGVPGPRGLPGLPGVPGM--------------------PG 575 PG GP G +G G +G G G +GL G PG PG G Sbjct: 206 PGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKG 265 Query: 576 PKGPPGPPGPSGAVVPLALQNEPTPAPEDNG 606 G PGPPGPSG +P AP D G Sbjct: 266 AMGEPGPPGPSG--LPGESYGSEKGAPGDPG 294 >gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo sapiens] Length = 1637 Score = 166 bits (421), Expect = 6e-41 Identities = 87/173 (50%), Positives = 104/173 (60%), Gaps = 16/173 (9%) Query: 441 LQGPPGPRGPRGDRGS---QGPPGPTGN---KGQKGEKGEPGPPGPAGERGPIGPAGPPG 494 L+G PG +G G G+ +G PGP G G+KG++G PG PG G GP GPAGPPG Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD-------PGPPGPPGKEGLPGPQGPPGFQ 547 G +G G QG +G G+PG PG GP G+ PGPPGPPG G PGPQGPPG Sbjct: 618 Y-GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIP 676 Query: 548 GLQGTVGEPGVPGPRGLPGLPGV--PGMPGPKGPPGPPGPSGAVVPLALQNEP 598 G G G+PG+PGP G PG+PG+ PG PGPKG G PG G++ EP Sbjct: 677 GSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEP 729 Score = 150 bits (380), Expect = 3e-36 Identities = 88/193 (45%), Positives = 96/193 (49%), Gaps = 20/193 (10%) Query: 432 GQLIKNFTILQGPPGPRGPRGDRGSQGPPGP--TGNKGQKGEKGEPGPPGPAGERGPIGP 489 G +I T +GPPG RG G G GPPG G KG KG G PGP GP G G +GP Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP 1290 Query: 490 AGP---------PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG---- 536 G PG RG G +G G KG +G+PG G GP G GP GPPG G Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGT 1350 Query: 537 -----LPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 LPG GPPG G G GEPG PGP G G G G PG G PG PGP+G Sbjct: 1351 LKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGN 1410 Query: 592 LALQNEPTPAPED 604 + EP PA D Sbjct: 1411 KGSKGEPGPAGSD 1423 Score = 149 bits (376), Expect = 9e-36 Identities = 87/209 (41%), Positives = 98/209 (46%), Gaps = 42/209 (20%) Query: 435 IKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG------ 488 +K L GP GP GPRGD GS G PG G +G G G G PG G+RG +G Sbjct: 980 LKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAG 1039 Query: 489 -----------------------PAGPPGERGGKGSKGSQGPKGSRGSPGKPG---PQGP 522 GPPG G G G G KG G PG PG P GP Sbjct: 1040 RPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGP 1099 Query: 523 SGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGP------ 576 G PG PG PG G PGP G GF+G++G +G PG+ GP PGLPG PG PGP Sbjct: 1100 EGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGP---PGLPGFPGSPGPMGIRGD 1156 Query: 577 KGPPGPPGPSGAVVPLALQNEPTPAPEDN 605 +G G PGP+G L P P P N Sbjct: 1157 QGRDGIPGPAGEKGETGLLRAP-PGPRGN 1184 Score = 145 bits (367), Expect = 1e-34 Identities = 98/222 (44%), Positives = 109/222 (49%), Gaps = 52/222 (23%) Query: 440 ILQGPPGPRG------PRGDRGSQGPPGPTGNKGQKGEKGEPGP------PGPAGERGPI 487 +L+ PPGPRG +GDRG+ G PG G KG G+ G GP PGP G G I Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233 Query: 488 GPA-----GPPGERGGKGSKGSQGP--------KGSRGSPGKPGPQGP---SGDPGPPG- 530 P GPPG RG G+ G GP KG +GS G PGP+GP +GD GPPG Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293 Query: 531 --PPGKEGLPGPQGPPGFQGLQGTVGEPG---------VPGPRGLPGLPGVPGMPGP--- 576 PG GLPGP+G PGFQG G GE G PGP G G PGV G PG Sbjct: 1294 LGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKI 1353 Query: 577 ---KGPPGPPGPSGAVVPLALQNEP-TPAPEDN--GCPPHWK 612 G PGPPG G +Q EP P P N C P K Sbjct: 1354 ISLPGSPGPPGTPGEP---GMQGEPGPPGPPGNLGPCGPRGK 1392 Score = 144 bits (363), Expect = 3e-34 Identities = 81/158 (51%), Positives = 91/158 (57%), Gaps = 9/158 (5%) Query: 439 TILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498 T + GPPGP GP G G QGPPG G+ G+ G+ G PGP G G G IG GPPG Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG-IGFPGPPGP--- 707 Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG--LPGPQGPPGFQGLQGTVGEP 556 KG +G G KGS G PGK G G G PG PG G+ +PG G PGF G +G GE Sbjct: 708 KGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767 Query: 557 GVPGPRGLPGLPGVPG---MPGPKGPPGPPGPSGAVVP 591 G G GLPGLPG PG + GP+G PG PGP G P Sbjct: 768 GEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGP 805 Score = 141 bits (355), Expect = 2e-33 Identities = 80/171 (46%), Positives = 92/171 (53%), Gaps = 26/171 (15%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQ------KGEKGEPGPPGPA---------GERGPI 487 GPPGP G G G +G PG G KGQ KGE+G+ G PGP+ GE G Sbjct: 901 GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLK 960 Query: 488 GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD---PGPPGPPGKEGLPGPQGPP 544 G AG PGE+G +G G G KG +G PG GP GP GD G PG PG G+PG G Sbjct: 961 GFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNM 1020 Query: 545 GFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGP--------PGPPGPSG 587 G G +G G G PG G PGLPG+ G+ G KG PGPPGP+G Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071 Score = 139 bits (351), Expect = 7e-33 Identities = 82/187 (43%), Positives = 93/187 (49%), Gaps = 24/187 (12%) Query: 442 QGPPGPRGPRGDRGSQGP---------------PGPTGNKGQKGEKGEPGPPGPAGERGP 486 +G PG +G +GD+G+ GP G GN G+KG +G PG PG G +G Sbjct: 927 RGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGL 986 Query: 487 IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF 546 GPAGPPG RG GS G+ G G RG PG G G G G G G G G G PG Sbjct: 987 PGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGI 1046 Query: 547 QGLQGTVGEPGV-----PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601 GLQG GEPG PGP G G PG+PG G KG G PGP G + P P A Sbjct: 1047 HGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAG----PEGA 1102 Query: 602 PEDNGCP 608 P G P Sbjct: 1103 PGSPGSP 1109 Score = 139 bits (350), Expect = 9e-33 Identities = 82/177 (46%), Positives = 94/177 (53%), Gaps = 21/177 (11%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG------PIGPAGP--PG 494 G PGP GP+GD+G G G G G+ GE G PG PG G +G P GP P PG Sbjct: 700 GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPG------PQGPSGDPGPP---GPPGK--EGLPGPQGP 543 ERG G G G G G PG PG P+G G PGPP GPPG+ EG G QG Sbjct: 760 ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819 Query: 544 PGFQGLQGTVGEPGVPGPRGLPGLPGV--PGMPGPKGPPGPPGPSGAVVPLALQNEP 598 PG GL+G G G GP+G PG+PG+ G PG G PG PG G + PL + P Sbjct: 820 PGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876 Score = 139 bits (349), Expect = 1e-32 Identities = 78/174 (44%), Positives = 94/174 (54%), Gaps = 13/174 (7%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +G PG G +G G G PG G++G KG +G PG G G +G G GPPG RG Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEY 346 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP-----QGPPGFQGLQGTVGEP 556 + KG G+PG PGP+G G GP GPPG G PG +G PG+ GL+G+ GE Sbjct: 347 YDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGER 406 Query: 557 GVPG--PRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 G PG G PG PG G PG G PGPPGP G +V + P P D+G P Sbjct: 407 GRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIV---FRKGP---PGDHGLP 454 Score = 138 bits (347), Expect = 2e-32 Identities = 93/232 (40%), Positives = 109/232 (46%), Gaps = 68/232 (29%) Query: 441 LQGPPGP---------RGPRGDRGSQGPPGPTGNKGQ---------------------KG 470 LQG PG G +G+RG G G G KGQ KG Sbjct: 295 LQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG 354 Query: 471 EKGEPGPPGPAGERGPIGPAGPPGERGGKGSK-----------GSQGPKGSRGSPGK--- 516 ++G PGPPGP G RGP GP+GPPG G GS G +G KG RG PGK Sbjct: 355 DEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAM 414 Query: 517 --PGPQGPSGDPGPPGPPGKEGLPGP----QGPPGFQGLQGTVGEPGVP---GPRGLPGL 567 PG G +G PG PG PG G PG +GPPG GL G +G PG+P GP+G PGL Sbjct: 415 GTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGL 474 Query: 568 -----------PGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 PG+PG+PG G G PG GA L+ P +P + G P Sbjct: 475 LCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA---GLKGSP-GSPGNTGLP 522 Score = 138 bits (347), Expect = 2e-32 Identities = 76/163 (46%), Positives = 81/163 (49%), Gaps = 24/163 (14%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQ------------------KGEKGEPGPPGPAGER 484 G PGP+GP G G GPPG G G KGEKG PG G G Sbjct: 1274 GHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPP 1333 Query: 485 GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPP 544 GPIGP GPPG RG G+ GS G PG PG G G+PGPPGPPG G GP+G P Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393 Query: 545 GFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G G+PG PGP G G G G PGP G G PG G Sbjct: 1394 GKD------GKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKG 1430 Score = 137 bits (345), Expect = 4e-32 Identities = 73/154 (47%), Positives = 86/154 (55%), Gaps = 9/154 (5%) Query: 443 GPPGPRGP---RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499 GPPG G G G+ GPPGP GN G G++G PG PG G+RG G G G++G Sbjct: 883 GPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNP 942 Query: 500 GSK------GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553 G G +G G +G G PG +G G PG PG G +GLPGP GPPG +G G+ Sbjct: 943 GPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGST 1002 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G PG PG RG+PG G GMPG KG G G G Sbjct: 1003 GNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036 Score = 135 bits (341), Expect = 1e-31 Identities = 78/180 (43%), Positives = 90/180 (50%), Gaps = 23/180 (12%) Query: 442 QGPPGPRGPRGD--------------RGSQGPPGPTGNKGQKGEKGEPGPPG---PAGER 484 QG G GP+GD GS G PG G G G++G PG PG P GE Sbjct: 829 QGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGED 888 Query: 485 GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQ--- 541 G IG G PG G G G+ G G RGSPG PG +G G PG G G +G PGP Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEIS 948 Query: 542 ---GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598 G G GL+G G PG G RG+PG+PG+ G+ G GP GPPGP G + EP Sbjct: 949 HVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEP 1008 Score = 135 bits (341), Expect = 1e-31 Identities = 91/228 (39%), Positives = 105/228 (46%), Gaps = 48/228 (21%) Query: 421 MEEMKLVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQ-----------GPPGPTGN---K 466 M M + SK + F G PG G G +G + GPPGPTG+ Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076 Query: 467 GQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGP------KGSRGSPGKPGPQ 520 G G+KGE G PGP G GP GP G PG G G G GP KG +G G PG + Sbjct: 1077 GDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIR 1136 Query: 521 GPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV----PGPRGLP---------GL 567 GP G PG PG PG G+ G QG G G G GE G+ PGPRG P G Sbjct: 1137 GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGA 1196 Query: 568 PGVPGMP---------GPKGP------PGPPGPSGAVVPLALQNEPTP 600 PG PG+P GP+GP PGPPG GA++P N P Sbjct: 1197 PGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPP 1244 Score = 135 bits (341), Expect = 1e-31 Identities = 80/177 (45%), Positives = 89/177 (50%), Gaps = 6/177 (3%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PG GPRGD G QG PG G KG G G GPPGP G +GP G G PG Sbjct: 1298 GTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLP 1357 Query: 503 GSQGPKGSRGSP---GKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559 GS GP G+ G P G+PGP GP G+ GP GP GK G G G PG G +G G G P Sbjct: 1358 GSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEP 1417 Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA-PEDNGCPPHWKNFT 615 GP G GLPG+ G G G P G V Q P+ PE G P + F+ Sbjct: 1418 GPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPE--GTVPLYSGFS 1472 Score = 133 bits (335), Expect = 5e-31 Identities = 84/215 (39%), Positives = 103/215 (47%), Gaps = 53/215 (24%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG- 500 +G PG +G G+ G +G G G G KG KG PGP GP G RG +G G PGE G +G Sbjct: 954 KGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGI 1013 Query: 501 -----------SKGSQGP------------------KGSRGSPG-----KPGPQGPSGDP 526 SKG +G +G +G PG +PGP GP+GDP Sbjct: 1014 PGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDP 1073 Query: 527 GPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLP------------GVPGMP 574 G PG GK+G G GPPG G G G PG PG GLPG P G+ G P Sbjct: 1074 GLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPP 1133 Query: 575 GPKGPPGPPGPSGAVVPLALQNE------PTPAPE 603 G +GPPG PG G+ P+ ++ + P PA E Sbjct: 1134 GIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE 1168 Score = 132 bits (332), Expect = 1e-30 Identities = 69/159 (43%), Positives = 81/159 (50%), Gaps = 20/159 (12%) Query: 446 GPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQ 505 G +G +G++G GPPG G KG G +G PGP GP G G G G G RG G G Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 506 GPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV------------ 553 G G G+PG GP G G PG G G++G PG G G+ G+ G Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162 Query: 554 --------GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPG 584 G+PG+PG G GLPG PG PGP GPPGPPG Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPG 201 Score = 129 bits (325), Expect = 8e-30 Identities = 72/154 (46%), Positives = 82/154 (53%), Gaps = 26/154 (16%) Query: 464 GNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPS 523 G KG+KGEKG PGPPG G++G GP G PG +G KG G G GS+G G G G S Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 524 GDPGPPGPPGK---------EGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGL------- 567 G PG PG PG G G +G GF GL GT+G PG+PG GL G Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162 Query: 568 ----------PGVPGMPGPKGPPGPPGPSGAVVP 591 PG+PG PGP+G PGPPG G V P Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP 196 Score = 129 bits (324), Expect = 1e-29 Identities = 82/194 (42%), Positives = 90/194 (46%), Gaps = 31/194 (15%) Query: 441 LQGPPGPRGPRGDRG-SQGPPGPTGNKGQKGEKGEPGPPGPAGERG-----------PIG 488 L G PGP GP GD +GPPG G G G G PG GP GE G P G Sbjct: 428 LPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPG 487 Query: 489 PAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPG-------PQ 541 G PG G KG G QG G +GSPG PG G G PG PG G GL G P+ Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPE 547 Query: 542 GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKG------------PPGPPGPSGAV 589 G G G G G+PG G G+PG PGV G+PGPKG PPG PG G+ Sbjct: 548 GQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSP 607 Query: 590 VPLALQNEPTPAPE 603 P P P+ Sbjct: 608 GPAGPAGPPGYGPQ 621 Score = 125 bits (315), Expect = 1e-28 Identities = 79/186 (42%), Positives = 88/186 (47%), Gaps = 34/186 (18%) Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQK------GEKGEPGPPGPAGERGPIGP 489 K FT +G PGP+GP +G G PG TG+KG + G G PG PG G GP G Sbjct: 63 KGFTGPEGLPGPQGP---KGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGL 119 Query: 490 AGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPP-----------GPPGKEGLP 538 G PG G KG +G G G+ G PG PG G G G P G PG G P Sbjct: 120 VGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAP 179 Query: 539 GPQGPPGFQGLQGTVGEPGVPGPRGLPG--------------LPGVPGMPGPKGPPGPPG 584 GPQG PG G G VG PG PG G PG + G G G KG GPPG Sbjct: 180 GPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPG 239 Query: 585 PSGAVV 590 P G V+ Sbjct: 240 PPGTVI 245 Score = 124 bits (312), Expect = 2e-28 Identities = 75/184 (40%), Positives = 89/184 (48%), Gaps = 39/184 (21%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGN--------KGQKGEKGEPGPPGPAGE-----RGPIGP 489 GPPGP G G G+ GP GP G+ KG++G KG GPPGP G GP Sbjct: 195 GPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNR 254 Query: 490 AGPPGERGGKGSKGSQGPKG-----------SRGSPGKPGPQGPSGDPGPPGPPGKEGL- 537 GE+G KG+ G GP G +G+PG PG QG G G PG PG EG+ Sbjct: 255 TDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVK 314 Query: 538 -----PGPQGPPGFQGLQGTVGEPGVPGP---------RGLPGLPGVPGMPGPKGPPGPP 583 PG G G +G +G +G PG GP +G G PG PG G +GP GP Sbjct: 315 GNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPS 374 Query: 584 GPSG 587 GP G Sbjct: 375 GPPG 378 Score = 124 bits (311), Expect = 3e-28 Identities = 77/176 (43%), Positives = 85/176 (48%), Gaps = 36/176 (20%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP-------IGPAGPP 493 ++G PG +G G +GS G PG TG G G G G PG GE+G +G G P Sbjct: 497 VKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDP 556 Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGPQGP------SGDPGPPGPPGKEGLPGPQGPPGFQ 547 G RG G KG G G+ G G PGP+G GD GPPG PG G PGP GP G Sbjct: 557 GLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPP 616 Query: 548 GLQGTVGEPGVPGPRGLPGLPGVPGMPGP----------------KGPPGPPGPSG 587 G G GEPG L G GVPG PGP GPPGPPGP G Sbjct: 617 GY-GPQGEPG------LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665 Score = 124 bits (310), Expect = 4e-28 Identities = 89/233 (38%), Positives = 99/233 (42%), Gaps = 67/233 (28%) Query: 443 GPPGP-------RGPRGDRGSQGPPGPTGNKGQKGEKGEPG-----------PPGPAGER 484 GPPGP +GP GD G G G G G G KGEPG PPG G Sbjct: 433 GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLP 492 Query: 485 GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPG----------PPGPPGK 534 G G G PG +G G KGS G G+ G PG PG G GDPG P G G Sbjct: 493 GLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGV 552 Query: 535 EGLPGPQGPPGFQGLQGTVGEPGV---PGPRGL------------PGLPGVPGMPGPKGP 579 G PG +G PG +GL G G PGV PGP+G PG PG PG PGP GP Sbjct: 553 PGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGP 612 Query: 580 -----------------------PGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609 PGPPG +G L++ + P P P PP Sbjct: 613 AGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSV-STPVPGPPGPPGPP 664 Score = 122 bits (306), Expect = 1e-27 Identities = 77/179 (43%), Positives = 90/179 (50%), Gaps = 34/179 (18%) Query: 443 GPPGPRGPRGDRGS------QGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPA------ 490 G PG RG G+ G G PG GN+G G +G+PG PGP GE+GP G Sbjct: 756 GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815 Query: 491 --GPPGERGGKGSKGSQGPKGSRGSPGKPGPQ-----GPSGDPGPPG------PPGKEGL 537 G PG G KG +G +G G +G PG PG G +G PG PG P G+ G Sbjct: 816 AQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGY 875 Query: 538 PGPQG---PPGFQGLQGTVGEPGV---PGPRGLPGLP---GVPGMPGPKGPPGPPGPSG 587 PG G PPG G+ G +G PG PGP G PG P G PG+PG KG G PG G Sbjct: 876 PGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKG 934 Score = 117 bits (292), Expect = 5e-26 Identities = 74/173 (42%), Positives = 82/173 (47%), Gaps = 36/173 (20%) Query: 451 RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGE---RGPIGPAGPPGERGGK--GSKGSQ 505 +GD G G PGP G G G G GPPGP G G +GP GP G G + G KG + Sbjct: 170 KGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGER 229 Query: 506 GPKGSRGSPGKPGP-----------------QGPSGDPGPPGPPGKEGLPGP-----QGP 543 G KG G PG PG +G G G PGPPG GLPG +G Sbjct: 230 GVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGA 289 Query: 544 PGFQGLQGTVGEPGVP---------GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 PG GLQG G+ GVP G RG PGL G G+ G KG GPPG G Sbjct: 290 PGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRG 342 Score = 115 bits (289), Expect = 1e-25 Identities = 80/211 (37%), Positives = 91/211 (43%), Gaps = 32/211 (15%) Query: 426 LVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG 485 L SK + I G PG G G+ G G G G G KGE+G PG PG G G Sbjct: 86 LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145 Query: 486 PIGPAGPPGERGGKG--------SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL 537 G AG G++G +KG G G+ G G PGP G G GPPGPPG G Sbjct: 146 IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205 Query: 538 PGPQGPPGFQGLQG--TVGEPGVPGPRGLPGLPGVPGM--------------------PG 575 PG GP G +G G +G G G +GL G PG PG G Sbjct: 206 PGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKG 265 Query: 576 PKGPPGPPGPSGAVVPLALQNEPTPAPEDNG 606 G PGPPGPSG +P AP D G Sbjct: 266 AMGEPGPPGPSG--LPGESYGSEKGAPGDPG 294 >gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo sapiens] Length = 1670 Score = 166 bits (421), Expect = 6e-41 Identities = 87/173 (50%), Positives = 104/173 (60%), Gaps = 16/173 (9%) Query: 441 LQGPPGPRGPRGDRGS---QGPPGPTGN---KGQKGEKGEPGPPGPAGERGPIGPAGPPG 494 L+G PG +G G G+ +G PGP G G+KG++G PG PG G GP GPAGPPG Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD-------PGPPGPPGKEGLPGPQGPPGFQ 547 G +G G QG +G G+PG PG GP G+ PGPPGPPG G PGPQGPPG Sbjct: 618 Y-GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIP 676 Query: 548 GLQGTVGEPGVPGPRGLPGLPGV--PGMPGPKGPPGPPGPSGAVVPLALQNEP 598 G G G+PG+PGP G PG+PG+ PG PGPKG G PG G++ EP Sbjct: 677 GSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEP 729 Score = 150 bits (380), Expect = 3e-36 Identities = 88/193 (45%), Positives = 96/193 (49%), Gaps = 20/193 (10%) Query: 432 GQLIKNFTILQGPPGPRGPRGDRGSQGPPGP--TGNKGQKGEKGEPGPPGPAGERGPIGP 489 G +I T +GPPG RG G G GPPG G KG KG G PGP GP G G +GP Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP 1290 Query: 490 AGP---------PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG---- 536 G PG RG G +G G KG +G+PG G GP G GP GPPG G Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGT 1350 Query: 537 -----LPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 LPG GPPG G G GEPG PGP G G G G PG G PG PGP+G Sbjct: 1351 LKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGN 1410 Query: 592 LALQNEPTPAPED 604 + EP PA D Sbjct: 1411 KGSKGEPGPAGSD 1423 Score = 149 bits (376), Expect = 9e-36 Identities = 87/209 (41%), Positives = 98/209 (46%), Gaps = 42/209 (20%) Query: 435 IKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG------ 488 +K L GP GP GPRGD GS G PG G +G G G G PG G+RG +G Sbjct: 980 LKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAG 1039 Query: 489 -----------------------PAGPPGERGGKGSKGSQGPKGSRGSPGKPG---PQGP 522 GPPG G G G G KG G PG PG P GP Sbjct: 1040 RPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGP 1099 Query: 523 SGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGP------ 576 G PG PG PG G PGP G GF+G++G +G PG+ GP PGLPG PG PGP Sbjct: 1100 EGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGP---PGLPGFPGSPGPMGIRGD 1156 Query: 577 KGPPGPPGPSGAVVPLALQNEPTPAPEDN 605 +G G PGP+G L P P P N Sbjct: 1157 QGRDGIPGPAGEKGETGLLRAP-PGPRGN 1184 Score = 145 bits (367), Expect = 1e-34 Identities = 98/222 (44%), Positives = 109/222 (49%), Gaps = 52/222 (23%) Query: 440 ILQGPPGPRG------PRGDRGSQGPPGPTGNKGQKGEKGEPGP------PGPAGERGPI 487 +L+ PPGPRG +GDRG+ G PG G KG G+ G GP PGP G G I Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233 Query: 488 GPA-----GPPGERGGKGSKGSQGP--------KGSRGSPGKPGPQGP---SGDPGPPG- 530 P GPPG RG G+ G GP KG +GS G PGP+GP +GD GPPG Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293 Query: 531 --PPGKEGLPGPQGPPGFQGLQGTVGEPG---------VPGPRGLPGLPGVPGMPGP--- 576 PG GLPGP+G PGFQG G GE G PGP G G PGV G PG Sbjct: 1294 LGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKI 1353 Query: 577 ---KGPPGPPGPSGAVVPLALQNEP-TPAPEDN--GCPPHWK 612 G PGPPG G +Q EP P P N C P K Sbjct: 1354 ISLPGSPGPPGTPGEP---GMQGEPGPPGPPGNLGPCGPRGK 1392 Score = 144 bits (363), Expect = 3e-34 Identities = 81/158 (51%), Positives = 91/158 (57%), Gaps = 9/158 (5%) Query: 439 TILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498 T + GPPGP GP G G QGPPG G+ G+ G+ G PGP G G G IG GPPG Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG-IGFPGPPGP--- 707 Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG--LPGPQGPPGFQGLQGTVGEP 556 KG +G G KGS G PGK G G G PG PG G+ +PG G PGF G +G GE Sbjct: 708 KGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767 Query: 557 GVPGPRGLPGLPGVPG---MPGPKGPPGPPGPSGAVVP 591 G G GLPGLPG PG + GP+G PG PGP G P Sbjct: 768 GEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGP 805 Score = 141 bits (355), Expect = 2e-33 Identities = 80/171 (46%), Positives = 92/171 (53%), Gaps = 26/171 (15%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQ------KGEKGEPGPPGPA---------GERGPI 487 GPPGP G G G +G PG G KGQ KGE+G+ G PGP+ GE G Sbjct: 901 GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLK 960 Query: 488 GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD---PGPPGPPGKEGLPGPQGPP 544 G AG PGE+G +G G G KG +G PG GP GP GD G PG PG G+PG G Sbjct: 961 GFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNM 1020 Query: 545 GFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGP--------PGPPGPSG 587 G G +G G G PG G PGLPG+ G+ G KG PGPPGP+G Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071 Score = 139 bits (351), Expect = 7e-33 Identities = 82/187 (43%), Positives = 93/187 (49%), Gaps = 24/187 (12%) Query: 442 QGPPGPRGPRGDRGSQGP---------------PGPTGNKGQKGEKGEPGPPGPAGERGP 486 +G PG +G +GD+G+ GP G GN G+KG +G PG PG G +G Sbjct: 927 RGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGL 986 Query: 487 IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF 546 GPAGPPG RG GS G+ G G RG PG G G G G G G G G G PG Sbjct: 987 PGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGI 1046 Query: 547 QGLQGTVGEPGV-----PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601 GLQG GEPG PGP G G PG+PG G KG G PGP G + P P A Sbjct: 1047 HGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAG----PEGA 1102 Query: 602 PEDNGCP 608 P G P Sbjct: 1103 PGSPGSP 1109 Score = 139 bits (350), Expect = 9e-33 Identities = 82/177 (46%), Positives = 94/177 (53%), Gaps = 21/177 (11%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG------PIGPAGP--PG 494 G PGP GP+GD+G G G G G+ GE G PG PG G +G P GP P PG Sbjct: 700 GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPG------PQGPSGDPGPP---GPPGK--EGLPGPQGP 543 ERG G G G G G PG PG P+G G PGPP GPPG+ EG G QG Sbjct: 760 ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819 Query: 544 PGFQGLQGTVGEPGVPGPRGLPGLPGV--PGMPGPKGPPGPPGPSGAVVPLALQNEP 598 PG GL+G G G GP+G PG+PG+ G PG G PG PG G + PL + P Sbjct: 820 PGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876 Score = 139 bits (349), Expect = 1e-32 Identities = 78/174 (44%), Positives = 94/174 (54%), Gaps = 13/174 (7%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +G PG G +G G G PG G++G KG +G PG G G +G G GPPG RG Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEY 346 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP-----QGPPGFQGLQGTVGEP 556 + KG G+PG PGP+G G GP GPPG G PG +G PG+ GL+G+ GE Sbjct: 347 YDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGER 406 Query: 557 GVPG--PRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 G PG G PG PG G PG G PGPPGP G +V + P P D+G P Sbjct: 407 GRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIV---FRKGP---PGDHGLP 454 Score = 138 bits (347), Expect = 2e-32 Identities = 93/232 (40%), Positives = 109/232 (46%), Gaps = 68/232 (29%) Query: 441 LQGPPGP---------RGPRGDRGSQGPPGPTGNKGQ---------------------KG 470 LQG PG G +G+RG G G G KGQ KG Sbjct: 295 LQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG 354 Query: 471 EKGEPGPPGPAGERGPIGPAGPPGERGGKGSK-----------GSQGPKGSRGSPGK--- 516 ++G PGPPGP G RGP GP+GPPG G GS G +G KG RG PGK Sbjct: 355 DEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAM 414 Query: 517 --PGPQGPSGDPGPPGPPGKEGLPGP----QGPPGFQGLQGTVGEPGVP---GPRGLPGL 567 PG G +G PG PG PG G PG +GPPG GL G +G PG+P GP+G PGL Sbjct: 415 GTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGL 474 Query: 568 -----------PGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 PG+PG+PG G G PG GA L+ P +P + G P Sbjct: 475 LCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA---GLKGSP-GSPGNTGLP 522 Score = 138 bits (347), Expect = 2e-32 Identities = 76/163 (46%), Positives = 81/163 (49%), Gaps = 24/163 (14%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQ------------------KGEKGEPGPPGPAGER 484 G PGP+GP G G GPPG G G KGEKG PG G G Sbjct: 1274 GHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPP 1333 Query: 485 GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPP 544 GPIGP GPPG RG G+ GS G PG PG G G+PGPPGPPG G GP+G P Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393 Query: 545 GFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G G+PG PGP G G G G PGP G G PG G Sbjct: 1394 GKD------GKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKG 1430 Score = 137 bits (345), Expect = 4e-32 Identities = 73/154 (47%), Positives = 86/154 (55%), Gaps = 9/154 (5%) Query: 443 GPPGPRGP---RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499 GPPG G G G+ GPPGP GN G G++G PG PG G+RG G G G++G Sbjct: 883 GPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNP 942 Query: 500 GSK------GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553 G G +G G +G G PG +G G PG PG G +GLPGP GPPG +G G+ Sbjct: 943 GPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGST 1002 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G PG PG RG+PG G GMPG KG G G G Sbjct: 1003 GNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036 Score = 135 bits (341), Expect = 1e-31 Identities = 78/180 (43%), Positives = 90/180 (50%), Gaps = 23/180 (12%) Query: 442 QGPPGPRGPRGD--------------RGSQGPPGPTGNKGQKGEKGEPGPPG---PAGER 484 QG G GP+GD GS G PG G G G++G PG PG P GE Sbjct: 829 QGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGED 888 Query: 485 GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQ--- 541 G IG G PG G G G+ G G RGSPG PG +G G PG G G +G PGP Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEIS 948 Query: 542 ---GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598 G G GL+G G PG G RG+PG+PG+ G+ G GP GPPGP G + EP Sbjct: 949 HVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEP 1008 Score = 135 bits (341), Expect = 1e-31 Identities = 91/228 (39%), Positives = 105/228 (46%), Gaps = 48/228 (21%) Query: 421 MEEMKLVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQ-----------GPPGPTGN---K 466 M M + SK + F G PG G G +G + GPPGPTG+ Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076 Query: 467 GQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGP------KGSRGSPGKPGPQ 520 G G+KGE G PGP G GP GP G PG G G G GP KG +G G PG + Sbjct: 1077 GDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIR 1136 Query: 521 GPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV----PGPRGLP---------GL 567 GP G PG PG PG G+ G QG G G G GE G+ PGPRG P G Sbjct: 1137 GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGA 1196 Query: 568 PGVPGMP---------GPKGP------PGPPGPSGAVVPLALQNEPTP 600 PG PG+P GP+GP PGPPG GA++P N P Sbjct: 1197 PGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPP 1244 Score = 135 bits (341), Expect = 1e-31 Identities = 80/177 (45%), Positives = 89/177 (50%), Gaps = 6/177 (3%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PG GPRGD G QG PG G KG G G GPPGP G +GP G G PG Sbjct: 1298 GTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLP 1357 Query: 503 GSQGPKGSRGSP---GKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559 GS GP G+ G P G+PGP GP G+ GP GP GK G G G PG G +G G G P Sbjct: 1358 GSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEP 1417 Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA-PEDNGCPPHWKNFT 615 GP G GLPG+ G G G P G V Q P+ PE G P + F+ Sbjct: 1418 GPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPE--GTVPLYSGFS 1472 Score = 133 bits (335), Expect = 5e-31 Identities = 84/215 (39%), Positives = 103/215 (47%), Gaps = 53/215 (24%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG- 500 +G PG +G G+ G +G G G G KG KG PGP GP G RG +G G PGE G +G Sbjct: 954 KGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGI 1013 Query: 501 -----------SKGSQGP------------------KGSRGSPG-----KPGPQGPSGDP 526 SKG +G +G +G PG +PGP GP+GDP Sbjct: 1014 PGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDP 1073 Query: 527 GPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLP------------GVPGMP 574 G PG GK+G G GPPG G G G PG PG GLPG P G+ G P Sbjct: 1074 GLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPP 1133 Query: 575 GPKGPPGPPGPSGAVVPLALQNE------PTPAPE 603 G +GPPG PG G+ P+ ++ + P PA E Sbjct: 1134 GIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE 1168 Score = 132 bits (332), Expect = 1e-30 Identities = 69/159 (43%), Positives = 81/159 (50%), Gaps = 20/159 (12%) Query: 446 GPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQ 505 G +G +G++G GPPG G KG G +G PGP GP G G G G G RG G G Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 506 GPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV------------ 553 G G G+PG GP G G PG G G++G PG G G+ G+ G Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162 Query: 554 --------GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPG 584 G+PG+PG G GLPG PG PGP GPPGPPG Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPG 201 Score = 129 bits (325), Expect = 8e-30 Identities = 72/154 (46%), Positives = 82/154 (53%), Gaps = 26/154 (16%) Query: 464 GNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPS 523 G KG+KGEKG PGPPG G++G GP G PG +G KG G G GS+G G G G S Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 524 GDPGPPGPPGK---------EGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGL------- 567 G PG PG PG G G +G GF GL GT+G PG+PG GL G Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162 Query: 568 ----------PGVPGMPGPKGPPGPPGPSGAVVP 591 PG+PG PGP+G PGPPG G V P Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP 196 Score = 129 bits (324), Expect = 1e-29 Identities = 82/194 (42%), Positives = 90/194 (46%), Gaps = 31/194 (15%) Query: 441 LQGPPGPRGPRGDRG-SQGPPGPTGNKGQKGEKGEPGPPGPAGERG-----------PIG 488 L G PGP GP GD +GPPG G G G G PG GP GE G P G Sbjct: 428 LPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPG 487 Query: 489 PAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPG-------PQ 541 G PG G KG G QG G +GSPG PG G G PG PG G GL G P+ Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPE 547 Query: 542 GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKG------------PPGPPGPSGAV 589 G G G G G+PG G G+PG PGV G+PGPKG PPG PG G+ Sbjct: 548 GQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSP 607 Query: 590 VPLALQNEPTPAPE 603 P P P+ Sbjct: 608 GPAGPAGPPGYGPQ 621 Score = 125 bits (315), Expect = 1e-28 Identities = 79/186 (42%), Positives = 88/186 (47%), Gaps = 34/186 (18%) Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQK------GEKGEPGPPGPAGERGPIGP 489 K FT +G PGP+GP +G G PG TG+KG + G G PG PG G GP G Sbjct: 63 KGFTGPEGLPGPQGP---KGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGL 119 Query: 490 AGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPP-----------GPPGKEGLP 538 G PG G KG +G G G+ G PG PG G G G P G PG G P Sbjct: 120 VGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAP 179 Query: 539 GPQGPPGFQGLQGTVGEPGVPGPRGLPG--------------LPGVPGMPGPKGPPGPPG 584 GPQG PG G G VG PG PG G PG + G G G KG GPPG Sbjct: 180 GPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPG 239 Query: 585 PSGAVV 590 P G V+ Sbjct: 240 PPGTVI 245 Score = 124 bits (312), Expect = 2e-28 Identities = 75/184 (40%), Positives = 89/184 (48%), Gaps = 39/184 (21%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGN--------KGQKGEKGEPGPPGPAGE-----RGPIGP 489 GPPGP G G G+ GP GP G+ KG++G KG GPPGP G GP Sbjct: 195 GPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNR 254 Query: 490 AGPPGERGGKGSKGSQGPKG-----------SRGSPGKPGPQGPSGDPGPPGPPGKEGL- 537 GE+G KG+ G GP G +G+PG PG QG G G PG PG EG+ Sbjct: 255 TDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVK 314 Query: 538 -----PGPQGPPGFQGLQGTVGEPGVPGP---------RGLPGLPGVPGMPGPKGPPGPP 583 PG G G +G +G +G PG GP +G G PG PG G +GP GP Sbjct: 315 GNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPS 374 Query: 584 GPSG 587 GP G Sbjct: 375 GPPG 378 Score = 124 bits (311), Expect = 3e-28 Identities = 77/176 (43%), Positives = 85/176 (48%), Gaps = 36/176 (20%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP-------IGPAGPP 493 ++G PG +G G +GS G PG TG G G G G PG GE+G +G G P Sbjct: 497 VKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDP 556 Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGPQGP------SGDPGPPGPPGKEGLPGPQGPPGFQ 547 G RG G KG G G+ G G PGP+G GD GPPG PG G PGP GP G Sbjct: 557 GLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPP 616 Query: 548 GLQGTVGEPGVPGPRGLPGLPGVPGMPGP----------------KGPPGPPGPSG 587 G G GEPG L G GVPG PGP GPPGPPGP G Sbjct: 617 GY-GPQGEPG------LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665 Score = 124 bits (310), Expect = 4e-28 Identities = 89/233 (38%), Positives = 99/233 (42%), Gaps = 67/233 (28%) Query: 443 GPPGP-------RGPRGDRGSQGPPGPTGNKGQKGEKGEPG-----------PPGPAGER 484 GPPGP +GP GD G G G G G G KGEPG PPG G Sbjct: 433 GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLP 492 Query: 485 GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPG----------PPGPPGK 534 G G G PG +G G KGS G G+ G PG PG G GDPG P G G Sbjct: 493 GLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGV 552 Query: 535 EGLPGPQGPPGFQGLQGTVGEPGV---PGPRGL------------PGLPGVPGMPGPKGP 579 G PG +G PG +GL G G PGV PGP+G PG PG PG PGP GP Sbjct: 553 PGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGP 612 Query: 580 -----------------------PGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609 PGPPG +G L++ + P P P PP Sbjct: 613 AGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSV-STPVPGPPGPPGPP 664 Score = 122 bits (306), Expect = 1e-27 Identities = 77/179 (43%), Positives = 90/179 (50%), Gaps = 34/179 (18%) Query: 443 GPPGPRGPRGDRGS------QGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPA------ 490 G PG RG G+ G G PG GN+G G +G+PG PGP GE+GP G Sbjct: 756 GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815 Query: 491 --GPPGERGGKGSKGSQGPKGSRGSPGKPGPQ-----GPSGDPGPPG------PPGKEGL 537 G PG G KG +G +G G +G PG PG G +G PG PG P G+ G Sbjct: 816 AQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGY 875 Query: 538 PGPQG---PPGFQGLQGTVGEPGV---PGPRGLPGLP---GVPGMPGPKGPPGPPGPSG 587 PG G PPG G+ G +G PG PGP G PG P G PG+PG KG G PG G Sbjct: 876 PGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKG 934 Score = 117 bits (292), Expect = 5e-26 Identities = 74/173 (42%), Positives = 82/173 (47%), Gaps = 36/173 (20%) Query: 451 RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGE---RGPIGPAGPPGERGGK--GSKGSQ 505 +GD G G PGP G G G G GPPGP G G +GP GP G G + G KG + Sbjct: 170 KGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGER 229 Query: 506 GPKGSRGSPGKPGP-----------------QGPSGDPGPPGPPGKEGLPGP-----QGP 543 G KG G PG PG +G G G PGPPG GLPG +G Sbjct: 230 GVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGA 289 Query: 544 PGFQGLQGTVGEPGVP---------GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 PG GLQG G+ GVP G RG PGL G G+ G KG GPPG G Sbjct: 290 PGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRG 342 Score = 115 bits (289), Expect = 1e-25 Identities = 80/211 (37%), Positives = 91/211 (43%), Gaps = 32/211 (15%) Query: 426 LVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG 485 L SK + I G PG G G+ G G G G G KGE+G PG PG G G Sbjct: 86 LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145 Query: 486 PIGPAGPPGERGGKG--------SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL 537 G AG G++G +KG G G+ G G PGP G G GPPGPPG G Sbjct: 146 IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205 Query: 538 PGPQGPPGFQGLQG--TVGEPGVPGPRGLPGLPGVPGM--------------------PG 575 PG GP G +G G +G G G +GL G PG PG G Sbjct: 206 PGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKG 265 Query: 576 PKGPPGPPGPSGAVVPLALQNEPTPAPEDNG 606 G PGPPGPSG +P AP D G Sbjct: 266 AMGEPGPPGPSG--LPGESYGSEKGAPGDPG 294 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 166 bits (420), Expect = 7e-41 Identities = 91/198 (45%), Positives = 106/198 (53%), Gaps = 10/198 (5%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---PAGPPGERGG 498 +G GP GP G G+ G PGP G G+ G++GE GP GPAG GP+G PAGP G RG Sbjct: 1036 RGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGD 1095 Query: 499 KGSKGSQGP---KGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGE 555 KG G QG KG RG G GP GP G PG GP G G GP+GPPG G G G Sbjct: 1096 KGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGL 1155 Query: 556 PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPPHWKNFT 615 G+PGP G PG G G GP GPPGPPGP G P + + + P+ PP K Sbjct: 1156 NGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQ----PPQEKAHD 1211 Query: 616 DKCYYFSVEKEIFEDAKL 633 YY + + + D L Sbjct: 1212 GGRYYRADDANVVRDRDL 1229 Score = 165 bits (418), Expect = 1e-40 Identities = 92/191 (48%), Positives = 100/191 (52%), Gaps = 23/191 (12%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG------------PPGPAGERGPIG 488 +QGPPGP G G RG++G PGPTG G GE+G PG P GPAGERG G Sbjct: 456 VQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPG 515 Query: 489 PAGP---PGERGGKGSKGSQGPKGSRGSPGKPGPQG------PSGDPGPPGPPGKEGLPG 539 PAGP PGE G G G G KG GSPG PGP G P+G G PGPPG G G Sbjct: 516 PAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARG 575 Query: 540 PQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPT 599 G GF G +G GEPG G RG+PG PG G G G G GP G P + E Sbjct: 576 QAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQG 635 Query: 600 PA--PEDNGCP 608 PA P G P Sbjct: 636 PAGSPGFQGLP 646 Score = 165 bits (417), Expect = 2e-40 Identities = 87/197 (44%), Positives = 99/197 (50%), Gaps = 39/197 (19%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP---------- 492 GPPGP GP G G +GP G TG G+ GE G PGPPGPAGE+G G GP Sbjct: 893 GPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQ 952 Query: 493 -----------PGERGGK---------GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPP 532 PG+RG + G G QGP G+ G G PGP GP G GPPG Sbjct: 953 GIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGES 1012 Query: 533 GKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGP---------PGPP 583 G+EG PG +G PG G G G+ G GP G PG PG PG PGP GP GP Sbjct: 1013 GREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPA 1072 Query: 584 GPSGAVVPLALQNEPTP 600 GP+G V P+ + P Sbjct: 1073 GPAGPVGPVGARGPAGP 1089 Score = 164 bits (414), Expect = 4e-40 Identities = 80/148 (54%), Positives = 88/148 (59%), Gaps = 3/148 (2%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GPPGP G G G+ G PG G G G KG+ GPPGPAG GP GP G G G KG++ Sbjct: 806 GPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGAR 865 Query: 503 GSQGPKGSRGSPG---KPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559 GS GP G+ G PG + GP GPSG+ GPPGPPG G G +GP G G G GE G P Sbjct: 866 GSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPP 925 Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 GP G G G PG GP G PG PGP G Sbjct: 926 GPPGPAGEKGSPGADGPAGAPGTPGPQG 953 Score = 162 bits (411), Expect = 8e-40 Identities = 82/157 (52%), Positives = 90/157 (57%), Gaps = 15/157 (9%) Query: 443 GPPGP------RGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGER 496 GPPGP G +G RGS GPPG TG G G G PPGP+G GP GP GP G+ Sbjct: 848 GPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVG---PPGPSGNAGPPGPPGPAGKE 904 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 GGKG +G GP G G G PGP GP+G+ G PG G G PG GP G G +G VG P Sbjct: 905 GGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLP 964 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPP------GPPGPSG 587 G G RG PGLPG G PG +GP GPPGP G Sbjct: 965 GQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMG 1001 Score = 160 bits (405), Expect = 4e-39 Identities = 84/186 (45%), Positives = 97/186 (52%), Gaps = 27/186 (14%) Query: 443 GPPGPRGPRGD---------RGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPP 493 GPPGP GP G +G GP GP G++G +G +GEPGPPGPAG GP G G Sbjct: 332 GPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGAD 391 Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP------------- 540 G+ G KG+ G+ G G+ G PG GP GP G GPPGP G G PG Sbjct: 392 GQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEP 451 Query: 541 -----QGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQ 595 QGPPG G +G G G PGP GLPG PG G PG +G PG G +G P + Sbjct: 452 GPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGER 511 Query: 596 NEPTPA 601 P PA Sbjct: 512 GSPGPA 517 Score = 159 bits (403), Expect = 7e-39 Identities = 80/167 (47%), Positives = 92/167 (55%), Gaps = 9/167 (5%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG---PPGPAGERGPIGPAGPPGERGGK 499 G PG GP G RG GPPG G+ G+ G+ G PG PPGP G RG G AG PG +G + Sbjct: 209 GEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHR 268 Query: 500 G------SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553 G +KG GP G +G PG PG G G GP G PG+ G PG GP G +G G Sbjct: 269 GFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGAT 328 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP 600 G G PGP G G PG PG G KG GP GP G+ P ++ EP P Sbjct: 329 GAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGP 375 Score = 159 bits (403), Expect = 7e-39 Identities = 81/157 (51%), Positives = 88/157 (56%), Gaps = 18/157 (11%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG------------PIGPA 490 GP GP+G G G G PG G +G GE+G PG PGPAG RG P GPA Sbjct: 281 GPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPA 340 Query: 491 GPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQ 550 GPPG G G+KG GP+G RGS G PQG G+PGPPGP G G P G PG G Sbjct: 341 GPPGFPGAVGAKGEAGPQGPRGSEG---PQGVRGEPGPPGPAGAAG---PAGNPGADGQP 394 Query: 551 GTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G G G PG G PG PG G GP+GP GPPGP G Sbjct: 395 GAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKG 431 Score = 159 bits (402), Expect = 9e-39 Identities = 80/158 (50%), Positives = 89/158 (56%), Gaps = 9/158 (5%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQ------KGEKGEPGPPGPAGERGPIGPAGPPGER 496 G PG RGP G +G GPPGP GN G+ KG+ G G PGP G +GP GPAG G+R Sbjct: 410 GFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKR 469 Query: 497 GGKGSKGS---QGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553 G +G G GP G RG PG G G G GP GP G+ G PGP GP G G G Sbjct: 470 GARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRP 529 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 GE G+PG +GL G PG PG G GPPGP G G P Sbjct: 530 GEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGP 567 Score = 158 bits (400), Expect = 2e-38 Identities = 83/175 (47%), Positives = 92/175 (52%), Gaps = 7/175 (4%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 QG PG +G G+RG+ G PGP G++G G KG G PG G RG GP GPPG G G Sbjct: 721 QGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGD 780 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPP------GPPGKEGLPGPQGPPGFQGLQGTVGE 555 KG GP G G G G G G+PGPP GPPG +G PG +G PG G +G G Sbjct: 781 KGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGP 840 Query: 556 PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAV-VPLALQNEPTPAPEDNGCPP 609 PG GP G PG G G PG KG G GP GA P A P P N PP Sbjct: 841 PGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPP 895 Score = 158 bits (399), Expect = 2e-38 Identities = 78/149 (52%), Positives = 85/149 (57%), Gaps = 3/149 (2%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G GP GP G G GPPGP G +GQ G G PGP G AGE G G G PG G G Sbjct: 551 GKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPA 610 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGL---QGTVGEPGVP 559 G G G++G PG GP G G+ GP G PG +GLPGP GPPG G QG G+ G P Sbjct: 611 GKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAP 670 Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588 GP G G G PG G +GPPGP GP GA Sbjct: 671 GPSGARGERGFPGERGVQGPPGPAGPRGA 699 Score = 156 bits (394), Expect = 8e-38 Identities = 85/183 (46%), Positives = 96/183 (52%), Gaps = 30/183 (16%) Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG------------------- 476 + F G GP+GP G+RGS GP GP G+ G+ G GE G Sbjct: 493 RGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGK 552 Query: 477 --PPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGK 534 PPGPAG+ G GP GPPG RG G G GPKG+ G PGK G +G G PG GP GK Sbjct: 553 TGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGK 612 Query: 535 ------EGLPGPQGPPGFQGLQGTVGEP---GVPGPRGLPGLPGVPGMPGPKGPPGPPGP 585 +G PGP GP G +G QG G P G+PGP G PG G PG G G G PGP Sbjct: 613 DGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGP 672 Query: 586 SGA 588 SGA Sbjct: 673 SGA 675 Score = 155 bits (392), Expect = 1e-37 Identities = 87/201 (43%), Positives = 102/201 (50%), Gaps = 37/201 (18%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKG------------QKGEKGEPGPPGPAGERGPIGP 489 +GPPGP+G RG G+ G PG G++G G KGEPG PG G G +GP Sbjct: 244 RGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGP 303 Query: 490 AGPPGER---GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF 546 G PGER G G G++G G+ G+ G PGP GP+G PG PG G +G GPQGP G Sbjct: 304 RGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGS 363 Query: 547 QGLQGTVGEPGVPGP---------------------RGLPGLPGVPGMPGPKGPPGPPGP 585 +G QG GEPG PGP G PG+ G PG PG +GP GP GP Sbjct: 364 EGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGP 423 Query: 586 SGAVVPLALQNEPTPAPEDNG 606 G P EP AP G Sbjct: 424 GGPPGPKGNSGEP-GAPGSKG 443 Score = 155 bits (392), Expect = 1e-37 Identities = 77/152 (50%), Positives = 89/152 (58%), Gaps = 6/152 (3%) Query: 443 GPPG---PRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGP---AGPPGER 496 GPPG P G G+ G+QGPPGP G G++GE+G G PG G GP GP AG PGE+ Sbjct: 602 GPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQ 661 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G G G+ GP G+RG G PG +G G PGP GP G G PG G G G G G Sbjct: 662 GVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQ 721 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588 G PG +G+PG G G+PGPKG G GP GA Sbjct: 722 GAPGLQGMPGERGAAGLPGPKGDRGDAGPKGA 753 Score = 154 bits (390), Expect = 2e-37 Identities = 79/159 (49%), Positives = 91/159 (57%), Gaps = 12/159 (7%) Query: 442 QGPPGPRGPRGDRGSQGP---------PGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP 492 QGPPGP GP G+RG QGP PGP G G+ G+ GE G PG G GP G G Sbjct: 619 QGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGE 678 Query: 493 PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG---L 549 G G +G +G GP G RG+ G PG G GD G PG PG +G PG QG PG +G L Sbjct: 679 RGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGL 738 Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588 G G+ G GP+G G PG G+ G GP GPPGP+GA Sbjct: 739 PGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGA 777 Score = 154 bits (390), Expect = 2e-37 Identities = 84/176 (47%), Positives = 91/176 (51%), Gaps = 12/176 (6%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG------ERGPIGPAGPPGER 496 G PGP+G RGD G +G G G G +G G GPPGPAG E GP GPAGP G R Sbjct: 737 GLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGAR 796 Query: 497 GGKGSKGSQGPKGS---RGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553 G G +G GP G G PG G G G+PG G G G PGP GP G G G V Sbjct: 797 GAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNV 856 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609 G PG G RG G PG G PG G GPPGPSG P P PA ++ G P Sbjct: 857 GAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGP---PGPPGPAGKEGGKGP 909 Score = 152 bits (384), Expect = 1e-36 Identities = 85/179 (47%), Positives = 96/179 (53%), Gaps = 30/179 (16%) Query: 443 GPPGPRGPRG---DRGSQGPPGPTGNK------GQKGEKGEPGPPGPAGERGPIGPAGPP 493 GP G RG RG +RG QGPPGP G + G G KG+ G PG G +G G G P Sbjct: 671 GPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMP 730 Query: 494 GERGG------KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP------PGKEGLPGPQ 541 GERG KG +G GPKG+ GSPGK G +G +G GPPGP G+ G GP Sbjct: 731 GERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPA 790 Query: 542 GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPP---------GPPGPSGAVVP 591 GP G +G G GEPG PGP G G PG G PG KG P GPPGP+G P Sbjct: 791 GPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGP 849 Score = 151 bits (382), Expect = 2e-36 Identities = 77/150 (51%), Positives = 84/150 (56%), Gaps = 3/150 (2%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEP---GPPGPAGERGPIGPAGPPGERG 497 ++G PGP GP G G G PG G G KG G P G PG G RGP GP GP G G Sbjct: 369 VRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPG 428 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557 KG+ G G GS+G G G GP G GPPGP G+EG G +G PG GL G GE G Sbjct: 429 PKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERG 488 Query: 558 VPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 PG RG PG GV G GP G G PGP+G Sbjct: 489 GPGSRGFPGADGVAGPKGPAGERGSPGPAG 518 Score = 147 bits (372), Expect = 3e-35 Identities = 88/214 (41%), Positives = 96/214 (44%), Gaps = 64/214 (29%) Query: 439 TILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG------------- 485 T ++GP G GPRG RG GPPG G GQ G G PGPPGP G G Sbjct: 108 TGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGY 167 Query: 486 ------------PIGPAGP---PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPG 530 P+GP+GP PG G G +G QGP G G PG GP GP G PGPPG Sbjct: 168 DEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPG 227 Query: 531 ---------------------PPGKEGLPGPQGPP------GFQGLQGTVGEPGVPGPRG 563 P G GLPG G P GF GL G G+ G GP+G Sbjct: 228 KNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKG 287 Query: 564 LPGLPGVPGMPGPKGP---------PGPPGPSGA 588 PG PG G PG GP PG PGP+GA Sbjct: 288 EPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGA 321 Score = 146 bits (368), Expect = 8e-35 Identities = 81/172 (47%), Positives = 88/172 (51%), Gaps = 27/172 (15%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKG------EKGEPGPPGPAGERGP---------- 486 GP G RG G G+ GPPGPTG G G KGE GP GP G GP Sbjct: 317 GPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPP 376 Query: 487 -----IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQ 541 GPAG PG G G+KG+ G G G+PG PG +GPSG GP GPPG +G G Sbjct: 377 GPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEP 436 Query: 542 GPPGFQGLQGTVGEP------GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G PG +G G GEP G PGP G G G G PGP G PGPPG G Sbjct: 437 GAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERG 488 Score = 145 bits (367), Expect = 1e-34 Identities = 84/178 (47%), Positives = 94/178 (52%), Gaps = 13/178 (7%) Query: 442 QGPPGPRGPRGDR---GSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498 QG PGP GP G+ G QG PG G G G +GE G PG G +GP GPAGP RG Sbjct: 643 QGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGP---RGA 699 Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV 558 G+ G+ G KG G+PG PG QG G G PG G GLPGP+G G G +G G PG Sbjct: 700 NGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGK 759 Query: 559 PGPRGL------PGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP-TPAPEDNGCPP 609 G RGL PG G PG G GP GP GP+GA + EP P P PP Sbjct: 760 DGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPP 817 Score = 145 bits (366), Expect = 1e-34 Identities = 77/168 (45%), Positives = 90/168 (53%), Gaps = 9/168 (5%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PG +GP G G +GPPGP G G G GE G G G G G G PG +G +G Sbjct: 980 GEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGET 1039 Query: 503 GSQGPKGSRGSPGKPGPQGPSG------DPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G GP G+ G+PG PGP GP+G + GP GP G G G +GP G QG +G GE Sbjct: 1040 GPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGET 1099 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPP---GPSGAVVPLALQNEPTPA 601 G G RG+ G G G+ GP GPPG P GPSGA P + P A Sbjct: 1100 GEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSA 1147 Score = 144 bits (363), Expect = 3e-34 Identities = 84/198 (42%), Positives = 95/198 (47%), Gaps = 35/198 (17%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG--- 498 Q G GP+GD G +GP GP G G+ G G+PG PGP GP GP GPPG G Sbjct: 105 QETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPP---GPPGPPGPPGLGGNFAP 161 Query: 499 ----------------KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQG 542 G G GP+G G PG PGPQG G PG PG PG G GP+G Sbjct: 162 QLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRG 221 Query: 543 PPGFQGLQGTVGE------------PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVV 590 PPG G G GE PG G RGLPG G+PGM G +G G G G Sbjct: 222 PPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAG 281 Query: 591 PLALQNEPTPAPEDNGCP 608 P + EP +P +NG P Sbjct: 282 PAGPKGEP-GSPGENGAP 298 Score = 143 bits (360), Expect = 7e-34 Identities = 86/198 (43%), Positives = 98/198 (49%), Gaps = 38/198 (19%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---------PAGPP 493 G GPRG G+RG G PGP G +G G G GPPGP G GP G AGP Sbjct: 299 GQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQ 358 Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGP---QGPSGDPGPPGPPGKE---GLPGPQGPPGFQ 547 G R GS+GP+G RG PG PGP GP+G+PG G PG + G PG G PGF Sbjct: 359 GPR------GSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFP 412 Query: 548 GLQGTVGEP---GVPGPRGLPGLPGVPGM---------PGPKGPPGPPGPSGAVVPLALQ 595 G +G G G PGP+G G PG PG PGP G GPPGP+G + Sbjct: 413 GARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGAR 472 Query: 596 NEPTPA-----PEDNGCP 608 EP P P + G P Sbjct: 473 GEPGPTGLPGPPGERGGP 490 Score = 80.9 bits (198), Expect = 4e-15 Identities = 57/160 (35%), Positives = 62/160 (38%), Gaps = 44/160 (27%) Query: 472 KGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP 531 K PG P GE P+ P GS+ P + G +GP GD GP GP Sbjct: 79 KNCPGAEVPEGECCPVCP------------DGSESPTDQETT----GVEGPKGDTGPRGP 122 Query: 532 PGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPG---------------------- 569 G P GPPG G+ G G PG PGP G PG PG Sbjct: 123 RG------PAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGIS 176 Query: 570 VPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609 VPG GP GP G PGP GA P Q P E P Sbjct: 177 VPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGP 216 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 166 bits (419), Expect = 9e-41 Identities = 81/177 (45%), Positives = 95/177 (53%), Gaps = 21/177 (11%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PG G +G RG +G GP G G G KGE GP GP G GP+GP G PGERG G + Sbjct: 291 GAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQ 350 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPG---------------------PPGPPGKEGLPGPQ 541 G+ G +G+ G PGKPGP GP G PG P GP G+ G GP Sbjct: 351 GAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPP 410 Query: 542 GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598 GP G GL G +G G PG +G G PG G PG GPPG PGP G+ P ++ +P Sbjct: 411 GPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQP 467 Score = 160 bits (406), Expect = 3e-39 Identities = 84/172 (48%), Positives = 91/172 (52%), Gaps = 27/172 (15%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PG GP G G +GPPGP G G G GEPGP GPAG G G G GERG +G Sbjct: 1014 GTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDP 1073 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPG------------PPGPPGKEGLPGPQGP------- 543 G G GS+G+PG PGP G GD G PPG GK GLPGPQGP Sbjct: 1074 GPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDH 1133 Query: 544 --------PGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G +G G G PG PGP G G G+PG GP+GPPGP GPSG Sbjct: 1134 GDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSG 1185 Score = 159 bits (401), Expect = 1e-38 Identities = 88/182 (48%), Positives = 99/182 (54%), Gaps = 24/182 (13%) Query: 441 LQGPPGPRGP------RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG 494 L G PGP GP +G RG+QGPPG TG G G G PPGPAG GP GP G PG Sbjct: 880 LAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVG---PPGPAGAPGPAGPLGEPG 936 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPP---GFQGLQG 551 + +G G +G GS G G GP GP G PG G PG++G PGP GPP G G +G Sbjct: 937 K---EGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRG 993 Query: 552 TVGEPGVPGPRGLPGLPGVPGMP---------GPKGPPGPPGPSGAVVPLALQNEPTPAP 602 VG PG G RG+PGLPG G P G KGPPGP GP G+ P+ PA Sbjct: 994 IVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAG 1053 Query: 603 ED 604 D Sbjct: 1054 ND 1055 Score = 158 bits (399), Expect = 2e-38 Identities = 85/175 (48%), Positives = 97/175 (55%), Gaps = 18/175 (10%) Query: 441 LQGPPGP------RGPRGDRGSQGPPGPTG------NKGQKGEKGEPGPPGPAGERGPIG 488 +QGP GP RGPRGD G+ GPPGP G N+G G G PGP G GERGP+G Sbjct: 490 IQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVG 549 Query: 489 PAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG 548 +GP G +G G G G G+RG G PG QGP G GP G PG++G PGP G G +G Sbjct: 550 SSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRG 609 Query: 549 LQGTVGEPGVPGPRGLPGLP------GVPGMPGPKGPPGPPGPSGAVVPLALQNE 597 G++G PG G G PG P GVPG G G G GPSG V P L E Sbjct: 610 QPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGE 664 Score = 158 bits (399), Expect = 2e-38 Identities = 88/186 (47%), Positives = 98/186 (52%), Gaps = 24/186 (12%) Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG---------ERGP 486 + F G PGP+G +G+RG G GP G++G G GEPG PG G G Sbjct: 527 RGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGK 586 Query: 487 IGPAGPPGE------------RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGK 534 +GP G PGE RG GS G GPKGS G PGKPG G +G PG G PGK Sbjct: 587 LGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGK 646 Query: 535 EGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGP---PGPSGAVVP 591 +G GP GP G GL G GE G PGP G GLPG PG PG G PG PG GAV P Sbjct: 647 DGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGP 706 Query: 592 LALQNE 597 L + E Sbjct: 707 LGPRGE 712 Score = 155 bits (393), Expect = 1e-37 Identities = 81/159 (50%), Positives = 89/159 (55%), Gaps = 12/159 (7%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGPPGERG 497 L+G PG G GDRG GPPG G+KG GE G+PGP PGPAG G G G PG+RG Sbjct: 943 LRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRG 1002 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKE---GLPGPQGP------PGFQG 548 +G G GP G+ G G G G G PGP GPPG G PGP+GP PG G Sbjct: 1003 ERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDG 1062 Query: 549 LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G G+ G PGP GLPG G PG PGP G PG G G Sbjct: 1063 AVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRG 1101 Score = 155 bits (391), Expect = 2e-37 Identities = 81/167 (48%), Positives = 90/167 (53%), Gaps = 9/167 (5%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPA------GERGPIGPAGPPG 494 + G PGP+G RG G +G G GN G +G G GPPGPA GE GP G GPPG Sbjct: 769 IAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPG 828 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGP---SGDPGPPGPPGKEGLPGPQGPPGFQGLQG 551 RG GS+G GP G+ G G GP G G+PG PG G G PGPQG G G G Sbjct: 829 SRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHG 888 Query: 552 TVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598 G PG+ G RG G PG G PG G GPPGP+GA P EP Sbjct: 889 PNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEP 935 Score = 154 bits (390), Expect = 2e-37 Identities = 82/176 (46%), Positives = 95/176 (53%), Gaps = 10/176 (5%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +GP GP+G RG+ G GP G G G G G PG GP G G GP G G G G Sbjct: 395 RGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGP 454 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQ------GTVGE 555 +GS GP+G RG PG PG G G+ GP G PG G+ GP GPPG +G + GTVG Sbjct: 455 QGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGP 514 Query: 556 PGVPGPRGLP---GLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 PG G RG P G PG G+PGPKG G GP G+ P Q +P P + G P Sbjct: 515 PGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDP-GRPGEPGLP 569 Score = 154 bits (388), Expect = 4e-37 Identities = 83/177 (46%), Positives = 92/177 (51%), Gaps = 16/177 (9%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG---------PPGPAGERGPIGPAGPP 493 GPPG G RG GS G PGP G+ G G+ GE G PG GE GP GP GPP Sbjct: 600 GPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPP 659 Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553 G G +G +G GP G +G PG PGP G G PG G PG G GP GP G +G G Sbjct: 660 GLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGER 719 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP-------TPAPE 603 GEPG+ G G G+ G G GPKG PGP G G P LQ P TP P+ Sbjct: 720 GEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPK 776 Score = 152 bits (385), Expect = 8e-37 Identities = 75/145 (51%), Positives = 88/145 (60%), Gaps = 3/145 (2%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PGP GP G G+ G G G GQ+GE+G PG PGPAG G +GP G G+ KG Sbjct: 975 GQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGD---KGPP 1031 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G GP GS G G+PGP+GP+G+ G PG G G G +G PG GL G+ G PG PGP Sbjct: 1032 GPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPV 1091 Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSG 587 G PG G G PG +GP GPPG +G Sbjct: 1092 GAPGDAGQRGDPGSRGPIGPPGRAG 1116 Score = 152 bits (384), Expect = 1e-36 Identities = 86/210 (40%), Positives = 99/210 (47%), Gaps = 57/210 (27%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGE---KGEPGPPGPAGE---------------- 483 GPPG +GPRG+RG +G PGP G +G GE G+PG PGP G Sbjct: 135 GPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQ 194 Query: 484 -----------------RGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDP 526 G +GP GP G +G +G +G GP G G PG PGP GP G Sbjct: 195 MAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSR 254 Query: 527 GPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGM------------- 573 GP GPPGK PG G PG G G VG G PG RG PG PG+PG+ Sbjct: 255 GPEGPPGK---PGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPK 311 Query: 574 -----PGPKGPPGPPGPSGAVVPLALQNEP 598 PG KG GP GP GA+ PL + P Sbjct: 312 GEVGAPGSKGEAGPTGPMGAMGPLGPRGMP 341 Score = 152 bits (383), Expect = 1e-36 Identities = 82/175 (46%), Positives = 94/175 (53%), Gaps = 10/175 (5%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGE---RGPIGPAGPPGERGGK 499 G PGP GP G RG +GPPG G G+ G G PG G AG RG G G PG +G + Sbjct: 243 GDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHR 302 Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPG------PQGPPGFQGLQGTV 553 G KG +GPKG G+PG G GP+G G GP G G+PG PQG PG +G G Sbjct: 303 GHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMP 362 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 G+PG GP G+PG G PG PG KG GP G G P + E P P G P Sbjct: 363 GKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGP-PGPVGSP 416 Score = 152 bits (383), Expect = 1e-36 Identities = 91/213 (42%), Positives = 104/213 (48%), Gaps = 49/213 (23%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTG------------------NKGQKGEKGEPGPPGPAG 482 L GPPG RG G RG GP G G GQKG+ G PGP G AG Sbjct: 823 LVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAG 882 Query: 483 ERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP---PGKEGLPG 539 GP GP G PG +GG+G++G G G GS G+ GP GP+G PGP GP PGKEG PG Sbjct: 883 SPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPG 942 Query: 540 ---------------PQGPPGFQGLQGTVGEPGVPGPRGLPG---------LPGVPGMPG 575 P GPPG G +G GE G PGP G PG + G+PG G Sbjct: 943 LRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRG 1002 Query: 576 PKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 +G PG PGP+G + PT A D G P Sbjct: 1003 ERGMPGLPGPAGTPGKVG----PTGATGDKGPP 1031 Score = 151 bits (381), Expect = 2e-36 Identities = 86/196 (43%), Positives = 105/196 (53%), Gaps = 21/196 (10%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +G PGP G G +G+ G PGP G G G++G+PG GP G G G G PG +G +G Sbjct: 1070 RGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGD 1129 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG---LPGP---QGPPGFQGLQGTVGE 555 KG G +G RG G G G G PGPPGP G++G +PGP +GPPG G G G Sbjct: 1130 KGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGN 1189 Query: 556 PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP-----LAL--------QNEPTPAP 602 PG GP G PG+ G G GP+GPPG PGP G P AL ++ P P P Sbjct: 1190 PGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGDIMGHYDESMPDPLP 1249 Query: 603 E--DNGCPPHWKNFTD 616 E ++ P KN TD Sbjct: 1250 EFTEDQAAPDDKNKTD 1265 Score = 150 bits (380), Expect = 3e-36 Identities = 84/187 (44%), Positives = 94/187 (50%), Gaps = 42/187 (22%) Query: 443 GPPGPRGPRGD------RGSQGPPGPTGN------------------------------- 465 GPPGP GP G+ RG GPPG GN Sbjct: 804 GPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEP 863 Query: 466 --KGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPS 523 GQKG+ G PGP G AG GP GP G PG +GG+G++G G G GS G+ GP GP+ Sbjct: 864 GEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPA 923 Query: 524 GDPGPPGP---PGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPP 580 G PGP GP PGKEG PG +G PG G G G G PG G G PG G PGP GPP Sbjct: 924 GAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPP 983 Query: 581 GPPGPSG 587 GP G +G Sbjct: 984 GPAGTTG 990 Score = 150 bits (379), Expect = 4e-36 Identities = 78/160 (48%), Positives = 89/160 (55%), Gaps = 15/160 (9%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKG------QKGEKGEPGPPGPAGERGPIGPAGPPGER 496 GP GP G G+RG QGPPGPTG +G GE G+PG G G+ G +GP GP GER Sbjct: 654 GPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGER 713 Query: 497 GGKGSKGSQGPKG---SRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553 G G +G G G +G G GP GP G PGP G PG G PG QG PG +G+ GT Sbjct: 714 GNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTP 773 Query: 554 GEPG------VPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G G G G G G G+PGP GPPGP GP+G Sbjct: 774 GPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTG 813 Score = 150 bits (378), Expect = 5e-36 Identities = 82/174 (47%), Positives = 90/174 (51%), Gaps = 7/174 (4%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 L GP GP GP G G +G PGP G G G +G PG G G G +G AGP G G G Sbjct: 799 LPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPG 858 Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP---PGKEGLPGPQGPPGFQGLQGTVGEPG 557 KG G G +G G PGPQG +G PGP GP PG +G G QGPPG G G+ G G Sbjct: 859 VKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVG 918 Query: 558 VPGPRGLPGLPGVPGMPGPKGPP---GPPGPSGAVVPLALQNEPTPAPEDNGCP 608 PGP G PG G G PG +GPP G PG G V P P D G P Sbjct: 919 PPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAG-PPGGPGDKGDP 971 Score = 149 bits (377), Expect = 7e-36 Identities = 81/174 (46%), Positives = 93/174 (53%), Gaps = 7/174 (4%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GP G GP+G RG G PG G KG+ G KGEPGP G G GP G G G RG G+ Sbjct: 453 GPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTV 512 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G GP G RG+PG G G G PGP G G+ G G GP G QG G GEPG+PG R Sbjct: 513 GPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGAR 572 Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSGAVVP---LALQNEP----TPAPEDNGCPP 609 GL G PGV G G GP G PG G P + ++ +P P P+ + P Sbjct: 573 GLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDP 626 Score = 148 bits (373), Expect = 2e-35 Identities = 77/154 (50%), Positives = 86/154 (55%), Gaps = 9/154 (5%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GP G G RG G G PGP G G G G PG PG GE GP G GP G +G +G Sbjct: 348 GPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGET 407 Query: 503 GSQGPKGSRGSPGK------PGPQGPSGDPGPPGPPGKEG---LPGPQGPPGFQGLQGTV 553 G GP GS G PG PG +GP+G PG GPPG G PGPQG G QG++G Sbjct: 408 GPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQP 467 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G+PGVPG +G G G PG G +GP GPPG G Sbjct: 468 GDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEG 501 Score = 147 bits (371), Expect = 3e-35 Identities = 83/186 (44%), Positives = 92/186 (49%), Gaps = 29/186 (15%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK--- 499 G PG RG G G GP GP G G GE+GE GPPGP G +G GP GPPGE GGK Sbjct: 636 GVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGE-GGKPGD 694 Query: 500 ----GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGE 555 G G+ GP G RG G PG +G G G PG G G GP GP G G GT G+ Sbjct: 695 QGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGD 754 Query: 556 PGVPGPRGLPGLPGVPGMPGPKGP---------------------PGPPGPSGAVVPLAL 594 G PG +G+PG G+ G PGPKG PGP GP G P Sbjct: 755 TGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGE 814 Query: 595 QNEPTP 600 + EP P Sbjct: 815 KGEPGP 820 Score = 147 bits (371), Expect = 3e-35 Identities = 80/178 (44%), Positives = 90/178 (50%), Gaps = 17/178 (9%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG------------ERGPIGPA 490 G PGP GP G+ G +GPPG G+ G G G+ GP GP G + GP GP Sbjct: 924 GAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPP 983 Query: 491 GPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQ 550 GP G G +G G G +G RG PG PGP G G GP G G +G PGP GPPG G Sbjct: 984 GPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNG-- 1041 Query: 551 GTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP--APEDNG 606 VGEPG GP G G PG G G +G G PGP+G P P AP D G Sbjct: 1042 -PVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAG 1098 Score = 144 bits (364), Expect = 2e-34 Identities = 78/151 (51%), Positives = 83/151 (54%), Gaps = 9/151 (5%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PG RG G+ G QGP G G G GE G PGPPG G RG G G PG +G G Sbjct: 567 GLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDP 626 Query: 503 GSQGPKGS------RGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G G G+ RG+PGK G GPSG GPPG G+ G GP GP GFQGL G P Sbjct: 627 GKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLP---GPP 683 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G PG G PG GVPG PG GP GP G G Sbjct: 684 GPPGEGGKPGDQGVPGDPGAVGPLGPRGERG 714 Score = 144 bits (362), Expect = 4e-34 Identities = 81/175 (46%), Positives = 94/175 (53%), Gaps = 30/175 (17%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKG---------EKGEPGPPGPAGERGPIGPAGPP 493 GP GPRG RG+ G +G PG TG G+KG KG PGP G G+ GP G G P Sbjct: 705 GPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMP 764 Query: 494 GERG---------------GKGSKGSQGPKGSRGSPGK---PGPQGPSGDPGPPGPPGKE 535 GERG KG++G+ G G+RG PG PGP GP+G+ G PGP G Sbjct: 765 GERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLV 824 Query: 536 GLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGV---PGMPGPKGPPGPPGPSG 587 G PG +G PG +G G G G GP+G G PGV PG PG KG G PGP G Sbjct: 825 GPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQG 879 Score = 143 bits (361), Expect = 5e-34 Identities = 80/166 (48%), Positives = 87/166 (52%), Gaps = 9/166 (5%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG---PPGPAGERGPIGPAGP------ 492 QGPPGP G +G G GPPG G G +G G+PG P GP GERG G G Sbjct: 668 QGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGL 727 Query: 493 PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552 PGE+G G G GPKGS G G PG GP G G PG G G PGP+G G G +G Sbjct: 728 PGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGA 787 Query: 553 VGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598 G G G RGLPG G PG GP G G PGP G V P + P Sbjct: 788 EGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNP 833 Score = 142 bits (357), Expect = 1e-33 Identities = 72/151 (47%), Positives = 83/151 (54%), Gaps = 6/151 (3%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GP GP+G G G+ G GP G +G GE+G G PGP G+RG IG G G G G++ Sbjct: 738 GPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGAR 797 Query: 503 G------SQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G GP G G G+PGP+G G PG G PG G GP G GF G QG G+P Sbjct: 798 GLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQP 857 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 GV G G PG G G PGP+G G PGP G Sbjct: 858 GVKGEPGEPGQKGDAGSPGPQGLAGSPGPHG 888 Score = 122 bits (306), Expect = 1e-27 Identities = 88/269 (32%), Positives = 120/269 (44%), Gaps = 30/269 (11%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGER------GPIGPAGPPG 494 L GP GPRG +GD G +G G G++G G +G PGPPGP GE+ GP GP GPPG Sbjct: 1120 LPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPG 1179 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF--QGLQGT 552 G G +G+ GP G G PG +G G+ GP GPPG+ G PGP GPPG L Sbjct: 1180 PVGPSGKEGNPGP---LGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGDI 1236 Query: 553 VGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPPHWK 612 +G P LP P K PG + L+ Q E +P+ G H Sbjct: 1237 MGHYDESMPDPLPEFTEDQAAPDDKNKT-DPGVHATLKSLSSQIETMRSPD--GSKKHPA 1293 Query: 613 NFTDKC-----------YYFSVEKEIFEDA-KLFCEDKSSHLVFI---NTREEQQWIKKQ 657 D Y+ + EDA K++C ++ ++ + W + Sbjct: 1294 RTCDDLKLCHSAKQSGEYWIDPNQGSVEDAIKVYCNMETGETCISANPSSVPRKTWWASK 1353 Query: 658 MVGRESHWIGLTDSERENEWKWLDGTSPD 686 + W GL D R +++ + D SP+ Sbjct: 1354 SPDNKPVWYGL-DMNRGSQFAYGDHQSPN 1381 Score = 119 bits (299), Expect = 8e-27 Identities = 73/179 (40%), Positives = 85/179 (47%), Gaps = 39/179 (21%) Query: 456 SQGPPGPTGN--KGQKGEKGEPG-PPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRG 512 SQ P G N +G+KG+KGEPG P G RG GPAGPPG SQGP+G RG Sbjct: 97 SQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPG---------SQGPRGERG 147 Query: 513 SPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG------------------------ 548 G+PGP+GP G G PG PG+ G PGP G P G Sbjct: 148 PKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQ 207 Query: 549 ---LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPED 604 + G+VG G GP+GL G G G GP G PG PGP G + + P ED Sbjct: 208 VGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGED 266 Score = 92.4 bits (228), Expect = 1e-18 Identities = 62/167 (37%), Positives = 71/167 (42%), Gaps = 41/167 (24%) Query: 477 PPGPAGERGPIGPAGPPGERG--GKGSKGSQGPKGS----RGSPGKPGPQGPSGDPGPPG 530 P P GE P+ P G G+G KG +G G G G+PGP GP G GP G Sbjct: 85 PVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRG 144 Query: 531 PPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPG------------------ 572 G +G PGP+GP G G G G+PG PGP G P PG G Sbjct: 145 ERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGL 204 Query: 573 ------MPGPKGPPGPPGPSGAVVPLALQNE-----PTPAPEDNGCP 608 MPG GP GP GP G LQ + PT P + G P Sbjct: 205 GSQVGLMPGSVGPVGPRGPQG------LQGQQGGAGPTGPPGEPGDP 245 >gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] Length = 1745 Score = 165 bits (417), Expect = 2e-40 Identities = 79/147 (53%), Positives = 90/147 (61%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PG GP G RG G G G +G+KG KGEPGP GP G GP+G GPPG G +G + Sbjct: 1301 GEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLR 1360 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G GP G G G PG GP G GP G PG +G GP+G G GL G +G PG G + Sbjct: 1361 GIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEK 1420 Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSGAV 589 G GLPGV G PGPKG PGPPGP G++ Sbjct: 1421 GDQGLPGVQGPPGPKGDPGPPGPIGSL 1447 Score = 161 bits (407), Expect = 2e-39 Identities = 82/155 (52%), Positives = 96/155 (61%), Gaps = 9/155 (5%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGE---KGEPGPPGPAGERGPIGPAGPPGERGG 498 +G PG GP+GDRG G PG G KGQ+G+ G+PGPPG GERG GP GP G+ G Sbjct: 538 RGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGE 597 Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPP---GPPGKEGLPGPQGPPGFQGL---QGT 552 G +G GP+GS G G+PG G G PG GPPG+ G PG QG G QGL QG Sbjct: 598 PGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGL 657 Query: 553 VGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 +G PG GP G PG+PG+PG GP G PG GP+G Sbjct: 658 IGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTG 692 Score = 160 bits (404), Expect = 5e-39 Identities = 86/189 (45%), Positives = 101/189 (53%), Gaps = 23/189 (12%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQ---------------KGEKGEPGPPGPAGERGPI 487 GP GP+G G G +GPPG G KG+ KG G PGP GP GE+G Sbjct: 761 GPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKS 820 Query: 488 GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF- 546 G G PG G +G GS+G +G G+ G+PGP+G G G PG PG++GLPG QGPPGF Sbjct: 821 GKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFP 880 Query: 547 -----QGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP- 600 G QG G PG PG RG G G G PGP G GP G +G V PL + P P Sbjct: 881 GPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPP 940 Query: 601 -APEDNGCP 608 P + G P Sbjct: 941 GPPGEQGLP 949 Score = 157 bits (396), Expect = 4e-38 Identities = 77/145 (53%), Positives = 84/145 (57%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PGPRGP+G GS+G PG G GQ G GE G G AG+ GP G G PG +G G K Sbjct: 1172 GAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEK 1231 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G GP G+ G PGK GP G G G GP G G GP G PG G+ G+ GE G PG Sbjct: 1232 GDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDV 1291 Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSG 587 G PG PG G PG GPPG GPSG Sbjct: 1292 GGPGPPGASGEPGAPGPPGKRGPSG 1316 Score = 155 bits (393), Expect = 1e-37 Identities = 86/192 (44%), Positives = 99/192 (51%), Gaps = 36/192 (18%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 QG PG GPRG+ G +GP KGQ G+ GE GPPG AGE+G +G G PG G G Sbjct: 748 QGKPGAPGPRGEDGPEGP------KGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGP 801 Query: 502 KGS------QGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGE 555 KGS GP G +G GK G G G+ GPPG G+ G PG G PG +G G G Sbjct: 802 KGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGA 861 Query: 556 PGVPGPRGLPGLPGVPGMPGPKGPP------------------------GPPGPSGAVVP 591 PG+PG +GLPGL G PG PGPKGPP GPPGP+G + P Sbjct: 862 PGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGP 921 Query: 592 LALQNEPTPAPE 603 E P E Sbjct: 922 QGKTGEVGPLGE 933 Score = 155 bits (391), Expect = 2e-37 Identities = 92/197 (46%), Positives = 103/197 (52%), Gaps = 31/197 (15%) Query: 442 QGPPGP---------RGP---------RGDRGSQGPPGPTGNKGQKGEKGEPGP------ 477 +GPPGP RGP G GS+GP GP G KG +GE+G PGP Sbjct: 997 KGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGI 1056 Query: 478 PGPAGERGPIGPAGPPGERGGKGS------KGSQGPKGSRGSPGKPGPQGPSGDPGPPGP 531 PGP G GP G AGP GE G KG KGS+G KG G PG+PG +GP+G PGPPG Sbjct: 1057 PGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGA 1116 Query: 532 PGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 G +G GP G G +G G G GV GP GL GLPG PG G G G GP GA P Sbjct: 1117 DGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGP 1176 Query: 592 LALQNEPTPAPEDNGCP 608 Q PT + G P Sbjct: 1177 RGPQG-PTGSEGTPGLP 1192 Score = 154 bits (390), Expect = 2e-37 Identities = 84/180 (46%), Positives = 95/180 (52%), Gaps = 33/180 (18%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PGP G +G+ GSQG PGP G G GEKG PG PG G G GP G PG G G K Sbjct: 635 GEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEK 694 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQ---GLQGTVGEPGVP 559 G+QGP GS G PG PGP+G G G G G++G G G PGF+ GL+G G+PG P Sbjct: 695 GAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAP 754 Query: 560 GPR------------------------------GLPGLPGVPGMPGPKGPPGPPGPSGAV 589 GPR G+PGLPG PG PGPKG G PGP G + Sbjct: 755 GPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPI 814 Score = 154 bits (390), Expect = 2e-37 Identities = 81/155 (52%), Positives = 92/155 (59%), Gaps = 9/155 (5%) Query: 443 GPPGP---RGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG------ERGPIGPAGPP 493 GPPGP GP G RG GP G G+ G G KG+ GPPGP G ERGP+GPAG Sbjct: 962 GPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGI 1021 Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553 G G GS+G GP G +GS G+ GP GP+G G PGP G G PG GP G +G +G V Sbjct: 1022 GLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDV 1081 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588 G PG G +G G G PG PG +GP G PGP GA Sbjct: 1082 GAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGA 1116 Score = 154 bits (389), Expect = 3e-37 Identities = 97/221 (43%), Positives = 112/221 (50%), Gaps = 44/221 (19%) Query: 441 LQGPPG---PRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG--------------- 482 LQGPPG P+GP G +G G PG G +G+ G +G+ GPPGPAG Sbjct: 873 LQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLG 932 Query: 483 ERGPIGPAGPPGERGGKGSKGSQGPKGSRGSP---GKPGPQGPSGDPGP---PGPPGKEG 536 ERGP GP GPPGE+G G +G +G KG G P GK GP G G PGP PG PG G Sbjct: 933 ERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTG 992 Query: 537 LPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPP---------GPPGPS- 586 L G +GPPG G G+ GE G GP G GLPG G GP GP GPPGP+ Sbjct: 993 LKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTG 1052 Query: 587 -----GAVVPLALQNEPTPAPE-----DNGCPPHWKNFTDK 617 G + PL P+ E D G P H + DK Sbjct: 1053 KDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDK 1093 Score = 153 bits (386), Expect = 6e-37 Identities = 81/170 (47%), Positives = 88/170 (51%), Gaps = 9/170 (5%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G G +G RGD G GPPG G G KG+ GE G GP+G GP G GPPGE G KGS Sbjct: 1199 GAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSV 1258 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGP---------PGPPGKEGLPGPQGPPGFQGLQGTV 553 G G G G PG PG G G PG PGPPG G PG GPPG +G G + Sbjct: 1259 GPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHM 1318 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPE 603 G G G +G G PG G PG GP G GP G V P L+ P P E Sbjct: 1319 GREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGE 1368 Score = 151 bits (382), Expect = 2e-36 Identities = 80/177 (45%), Positives = 97/177 (54%), Gaps = 30/177 (16%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQ---------------KGEKGEPGPPGPAGERGP 486 +GPPG RG RG G+ G PGP G+ GQ +G G PGP GP G +G Sbjct: 832 RGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGK 891 Query: 487 IGPAGPPGERGGKGSKGSQGPK------GSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGP 540 G G PG+RG G +G GP G +G G+ GP G G PGPPGPPG++GLPG Sbjct: 892 DGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGL 951 Query: 541 Q---------GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588 + GPPG G +G G G PGP+G PG PG G+ G KGPPGP G +G+ Sbjct: 952 EGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGS 1008 Score = 150 bits (378), Expect = 5e-36 Identities = 83/186 (44%), Positives = 97/186 (52%), Gaps = 30/186 (16%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GPPG GP G+ G +G G G+KG KG+KG+ GPPG G RGP G GPPG G +G + Sbjct: 1064 GPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRR 1123 Query: 503 GSQG------------------PKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPP 544 G G P G +G PG PG +G GD G GP G G GPQGP Sbjct: 1124 GPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPT 1183 Query: 545 GFQG---LQGTVGEPGVPGPRGL------PGLPGVPGMPGPK---GPPGPPGPSGAVVPL 592 G +G L G VG+PG G +G PG PG PG+PGPK G G GPSGA P Sbjct: 1184 GSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPP 1243 Query: 593 ALQNEP 598 + P Sbjct: 1244 GKKGPP 1249 Score = 149 bits (377), Expect = 7e-36 Identities = 88/203 (43%), Positives = 99/203 (48%), Gaps = 57/203 (28%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP------PGPAGERGPIGPAGPPGER 496 GP G G G GS+GP GP G KG +GE+G PGP PGP G GP G AGP GE Sbjct: 1016 GPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEE 1075 Query: 497 GGKGS------KGSQGPKGSRGSPGKPGPQGPSGDPGPPG-------------------- 530 G KG KGS+G KG G PG+PG +GP+G PGPPG Sbjct: 1076 GDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDD 1135 Query: 531 ----------PPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRG---------LPGLPGVP 571 PPG +GLPGP G G G G++G G PGPRG PGLPG Sbjct: 1136 GVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGV 1195 Query: 572 GMP------GPKGPPGPPGPSGA 588 G P G +G G PGP GA Sbjct: 1196 GQPGAVGEKGERGDAGDPGPPGA 1218 Score = 149 bits (376), Expect = 9e-36 Identities = 87/198 (43%), Positives = 97/198 (48%), Gaps = 32/198 (16%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG------PPGPAGERGPIGPAGPPG 494 L G PG GP+G G GP GP G KG+ G+ G+PG PPG GERG G G PG Sbjct: 792 LPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPG 851 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPG--------------- 539 +G G G+ G G +G PG GP G G GPPG GK+G PG Sbjct: 852 PKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTG 911 Query: 540 PQGPPGFQGLQGTVGE---------PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVV 590 P GP G G QG GE PG PGP G GLPG+ G G KG GPPGP G Sbjct: 912 PPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEG 971 Query: 591 PLALQNEPTP--APEDNG 606 P L+ P P P D G Sbjct: 972 PAGLRGFPGPKGGPGDPG 989 Score = 147 bits (372), Expect = 3e-35 Identities = 80/184 (43%), Positives = 95/184 (51%), Gaps = 15/184 (8%) Query: 435 IKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG 494 ++ F +G PG GP G +G +GPPGP G G GE+G GP G G G G GP G Sbjct: 975 LRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVG 1034 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQ---- 550 G KGS+G +GP G G G PGP GP G PG GP G+EG G G PG +G + Sbjct: 1035 PAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKG 1094 Query: 551 --GTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPS---------GAVVPLALQNEPT 599 G G+PG+ GP G PG PG G G +GPPG G G + P LQ P Sbjct: 1095 DAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPG 1154 Query: 600 PAPE 603 P E Sbjct: 1155 PPGE 1158 Score = 147 bits (370), Expect = 5e-35 Identities = 83/186 (44%), Positives = 94/186 (50%), Gaps = 25/186 (13%) Query: 442 QGPPGPRGPRGDRGS------------QGPPGPTGNKGQKGEKGEPGP---PGPAGERGP 486 +GPPG G +GD G QG PGP G KG+ G+ G GP PGP G +GP Sbjct: 1123 RGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGP 1182 Query: 487 IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGP---------PGPPGKEGL 537 G G PG GG G G+ G KG RG G PGP G G PGP GP G G Sbjct: 1183 TGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGP 1242 Query: 538 PGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNE 597 PG +GPPG G +G+VG G+PG G PG PGV G+ G G G PG G P E Sbjct: 1243 PGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGE 1302 Query: 598 P-TPAP 602 P P P Sbjct: 1303 PGAPGP 1308 Score = 146 bits (369), Expect = 6e-35 Identities = 79/168 (47%), Positives = 89/168 (52%), Gaps = 12/168 (7%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PGP G G+RG++GPPGPT G+ GEPGP G G RG GP G PG G G+ Sbjct: 572 GQPGPPGEDGERGAEGPPGPT------GQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAP 625 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGL------QGTVGEP 556 G++G G G PG PG QG G G PGP G G PG +GPPG G+ G +G P Sbjct: 626 GAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHP 685 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPED 604 G GP G G G PG GP G PGP G G LQ E ED Sbjct: 686 GHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGED 733 Score = 144 bits (364), Expect = 2e-34 Identities = 77/158 (48%), Positives = 87/158 (55%), Gaps = 12/158 (7%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +G GP G G G +GPPG G KG G G PG GP G+ G G G PGE+G G Sbjct: 1231 KGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGD 1290 Query: 502 KGSQGPKGSRGSPGKPGP---QGPSGDPGPPGPPGKEGL---PGPQGPPGFQGLQGTVGE 555 G GP G+ G PG PGP +GPSG G G G++G PGP GPPG G G G Sbjct: 1291 VGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGP 1350 Query: 556 PGVPGPRGLPGL------PGVPGMPGPKGPPGPPGPSG 587 PG GP GL G+ PG+ G PG GPPGP GPSG Sbjct: 1351 PGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSG 1388 Score = 144 bits (362), Expect = 4e-34 Identities = 75/163 (46%), Positives = 88/163 (53%), Gaps = 3/163 (1%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 + G PG GP G G +GP G G +G G G PG PGP G +G G G GE+G KG Sbjct: 672 IPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKG 731 Query: 501 SKGSQGPKGS---RGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557 G G KG +G GKPG GP G+ GP GP G+ G G +GPPG G +G +G PG Sbjct: 732 EDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPG 791 Query: 558 VPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP 600 +PG G PG G G PGP GP G G SG L+ E P Sbjct: 792 LPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGP 834 Score = 140 bits (354), Expect = 3e-33 Identities = 84/191 (43%), Positives = 98/191 (51%), Gaps = 23/191 (12%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP---IGPAGPPGERG 497 ++GPPGP G G G G PG G KG++G +G GP G G GP +G G PG G Sbjct: 477 MKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADG 536 Query: 498 GKGSKGSQGPKGSRGS---PGKPGPQGPSGD------PGPPGPPGK---EGLPGPQGPPG 545 +G G GPKG RG PG PG +G GD PGPPG G+ EG PGP G G Sbjct: 537 ARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAG 596 Query: 546 FQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKG---PPGPPGPSGAVVPLALQNEPTP-- 600 G +G +G G PGP G PG+ G+ G PG KG PPG PGP G Q P P Sbjct: 597 EPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQG 656 Query: 601 ---APEDNGCP 608 P + G P Sbjct: 657 LIGTPGEKGPP 667 Score = 139 bits (350), Expect = 9e-33 Identities = 85/198 (42%), Positives = 95/198 (47%), Gaps = 36/198 (18%) Query: 442 QGPPGPRG------PRGDRGSQGPPGPTGN------------KGQKGEKGEPGPPGPAGE 483 +GPPGP G PRG G +G PGPTG KG G GEPGPPG G Sbjct: 586 EGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGN 645 Query: 484 R------GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL 537 GP G G PGE+G G+ G G GS G G PG +GP+G+ G GPPG G Sbjct: 646 HGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGP 705 Query: 538 PGPQGPPGF------QGLQGTVGE------PGVPGPRGLPGLPGVPGMPGPKGPPGPPGP 585 PG GP G +GLQG GE PG G GL G G PG PGP+G GP GP Sbjct: 706 PGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGP 765 Query: 586 SGAVVPLALQNEPTPAPE 603 G + P A E Sbjct: 766 KGQAGQAGEEGPPGSAGE 783 Score = 134 bits (337), Expect = 3e-31 Identities = 74/162 (45%), Positives = 81/162 (50%), Gaps = 18/162 (11%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 + GP G G G G GPPGP G G G KG+ GP G G G IG GPPGE Sbjct: 1362 IPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEA---- 1417 Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPG 560 G KG +G PG GP GP GDPGPPGP G G PGP G G G +G+ G PG G Sbjct: 1418 -----GEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMG 1472 Query: 561 PRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAP 602 PR G GP GPPGPPG + L + P P Sbjct: 1473 PR---------GDTGPAGPPGPPGAPAELHGLRRRRRFVPVP 1505 Score = 128 bits (321), Expect = 2e-29 Identities = 78/190 (41%), Positives = 85/190 (44%), Gaps = 45/190 (23%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGE----------------------KGEP----- 475 GP GP GP G G GPPGP G G G KG P Sbjct: 404 GPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQ 463 Query: 476 ---------------GPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQ 520 GPPGP G G GP G PG G KG +G++GP+G RG G GP Sbjct: 464 AQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPP 523 Query: 521 GPSGDPGPPGPPGKEGLPG---PQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPK 577 G G G PG G GLPG P+G GF GL G GE G G G G PG PG G + Sbjct: 524 GRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGER 583 Query: 578 GPPGPPGPSG 587 G GPPGP+G Sbjct: 584 GAEGPPGPTG 593 Score = 112 bits (281), Expect = 1e-24 Identities = 82/216 (37%), Positives = 96/216 (44%), Gaps = 50/216 (23%) Query: 438 FTILQGPPGPRGPRGD-----RGSQ--GPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPA 490 F I G G +G +G+ +G Q GPPG G +G G G PGPPG G+ GP GPA Sbjct: 366 FQIFPGA-GEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPA 424 Query: 491 GPPGERGGKGSKGSQG---------PKGS-RGSP--------------------GKPGPQ 520 G PG G G +G G GS +G P G PGP Sbjct: 425 GLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPV 484 Query: 521 GPSGDPGP---PGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPK 577 G +G PGP PG PG +G G +GP G +GLQG G PG G G PG G G+PG Sbjct: 485 GLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDT 544 Query: 578 GP---------PGPPGPSGAVVPLALQNEPTPAPED 604 GP PG PG G +P P ED Sbjct: 545 GPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGED 580 Score = 32.3 bits (72), Expect = 1.6 Identities = 23/60 (38%), Positives = 25/60 (41%), Gaps = 9/60 (15%) Query: 556 PGVPGPRGLPGLPGV-------PGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 PG G +G G P V G PG GP G GPSG P +P P P G P Sbjct: 370 PGA-GEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGP-PGPAGLP 427 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 162 bits (410), Expect = 1e-39 Identities = 88/173 (50%), Positives = 97/173 (56%), Gaps = 26/173 (15%) Query: 442 QGPPGPRGP---RGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAG---- 491 QGP G RG +GDRG GP G GN G GE+G GP PG G RGP GP G Sbjct: 2125 QGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGD 2184 Query: 492 --PPGERGGKGSKGSQGPKGSRGSPGKPGP-----QGPSGDPGPPGPPGKEGLPGPQGPP 544 PPG G G G QGP G +G PG+ GP GP+G G PGPPG GL GPQG P Sbjct: 2185 PGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSP 2244 Query: 545 GFQGLQGTVGEPGVP---------GPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588 G G G G+PG P G RG PG+PG PG+PGP GP G PGP+GA Sbjct: 2245 GLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGA 2297 Score = 154 bits (389), Expect = 3e-37 Identities = 91/201 (45%), Positives = 104/201 (51%), Gaps = 42/201 (20%) Query: 442 QGPPGPRGP------------RGDRGSQGPPG-------PTGNKGQKGEKGEPGPPGPAG 482 QGPPG GP RGD G QGPPG P G G GE G+PG PG G Sbjct: 1987 QGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPG 2046 Query: 483 ERGPIGPAGPPGERGGKGSKGSQG------PKGSRGSPGKPGPQGP-----------SGD 525 G +G AG PGERG +G KG +G P G G+PG PGP GP SG+ Sbjct: 2047 RAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGE 2106 Query: 526 PGPPGPPGKEGLPGP---QGPPGFQGLQGTVGEPGVPGPRGL---PGLPGVPGMPGPKGP 579 GPPG G +G PG QGP G +G+ G G+ G PGPRG PGLPG GM GP+G Sbjct: 2107 QGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGK 2166 Query: 580 PGPPGPSGAVVPLALQNEPTP 600 PG GP G P+ +P P Sbjct: 2167 PGLQGPRGPPGPVGGHGDPGP 2187 Score = 154 bits (388), Expect = 4e-37 Identities = 95/223 (42%), Positives = 105/223 (47%), Gaps = 60/223 (26%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGN--KGQKGEKGEPGPPGPA---------------GERG 485 GPPGPRGP GD G +GPPG G KG KG++GE GPPGP G G Sbjct: 1374 GPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPG 1433 Query: 486 PIGPAGPPGERGGKGSK-----------------------GSQGPKGSRGSPGKPGPQGP 522 P GP GPPG++G KG G+ GPKG RG PG G G Sbjct: 1434 PQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGE 1493 Query: 523 SGDPGPPGPPGKEGLPG---------PQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGM 573 G+ GPPGP G GLPG P+GPPG G QG GEPG PG + G P V G Sbjct: 1494 KGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVG-PAVAGP 1552 Query: 574 PGPKGPPGPPGPSGAV--------VPLALQNEPTPA--PEDNG 606 G KG GP GP GA L L +P P P D G Sbjct: 1553 KGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRG 1595 Score = 154 bits (388), Expect = 4e-37 Identities = 82/169 (48%), Positives = 90/169 (53%), Gaps = 7/169 (4%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKG----EKGEPGPPGPAGERGPIGPAGPPGERGG 498 G PG GP+GDRG GPPGP G G EKGEPG G G RGP G G PG G Sbjct: 1685 GSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGE 1744 Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV 558 +G +G +GP G +G PG GP G GD GPPG G+ GL G G G G G G+ G Sbjct: 1745 RGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGD 1804 Query: 559 PGPRGLPGLPGVPGMPGPKGP---PGPPGPSGAVVPLALQNEPTPAPED 604 PG GLPGL G G+PGP GP PG PG G EP ED Sbjct: 1805 PGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGED 1853 Score = 154 bits (388), Expect = 4e-37 Identities = 81/169 (47%), Positives = 96/169 (56%), Gaps = 17/169 (10%) Query: 446 GPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQ 505 GPRG +G+RG +G G G KG KGE G PG PG AG +G +G G PG+ G G +G Sbjct: 2620 GPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLI 2679 Query: 506 GPKGSRGSPGKPGPQGPSGDPGP---------PGPPGKEGLPGPQGPPGF------QGLQ 550 GPKG RG G+PGP+G G+ G PGP G +G GP GPPG +GLQ Sbjct: 2680 GPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQ 2739 Query: 551 GTVGEPGVPGPR--GLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNE 597 G GE G PG R G PG+PG PG G +G PGP GP G AL + Sbjct: 2740 GQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTED 2788 Score = 152 bits (385), Expect = 8e-37 Identities = 82/179 (45%), Positives = 97/179 (54%), Gaps = 31/179 (17%) Query: 440 ILQGPPGPRGPRGDRGS------QGPPGPTGNKGQKGEKGEPGPPGP---------AGER 484 +L G PGP+G GDRG GPPG +G G+KG+ G PGPPGP GE+ Sbjct: 1580 VLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEK 1639 Query: 485 GPIGPAGPP------GERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLP 538 G GP G P GERG +G+ G +GP G +G G PG G +G PG GP G G P Sbjct: 1640 GDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEP 1699 Query: 539 GPQGPPG----------FQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 GP GPPG +G G G+ G GP+G PGLPG PG G +G GPPGP G Sbjct: 1700 GPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQG 1758 Score = 151 bits (381), Expect = 2e-36 Identities = 93/229 (40%), Positives = 107/229 (46%), Gaps = 64/229 (27%) Query: 442 QGPPGPRGPRG---------DRGSQGPPGPTGNKGQKGEKGEPGPP--------GPAGER 484 +GPPGP G RG +G +GPPGPTG +G+KGE G PG P GP GE+ Sbjct: 1497 RGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEK 1556 Query: 485 GPIGPAGP-----------------PGERGGKGSKGSQGP---KGSRGSPGKPGPQGPSG 524 G +GPAGP PG+ G KG G +GP G G PG GP G G Sbjct: 1557 GDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKG 1616 Query: 525 DPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGP---RGLPGLPGV----------- 570 DPG PGPPG G G G G +G +G G+PG+PG RGL G PGV Sbjct: 1617 DPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQG 1676 Query: 571 ----------PGMPGPKGP---PGPPGPSGAVVPLALQNEPTPAPEDNG 606 PG GPKG PGPPGP G +V P D G Sbjct: 1677 DPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRG 1725 Score = 149 bits (376), Expect = 9e-36 Identities = 83/172 (48%), Positives = 96/172 (55%), Gaps = 22/172 (12%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +GPPG GP+GDRG PGP G G+KGE+ GPPGPAG RG G AG PG +G +G Sbjct: 1470 RGPPGAIGPKGDRGF---PGPLGEAGEKGER---GPPGPAGSRGLPGVAGRPGAKGPEGP 1523 Query: 502 KGSQGPKGSRGSPGKP-----------GPQGPSGDPGPPGPPGKEGLPGPQGPPG--FQG 548 G G +G +G PG+P GP+G GD GP GP G G+ G +GPPG G Sbjct: 1524 PGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPG 1583 Query: 549 LQGTVGEPGVPGPRGLPGLPGVP---GMPGPKGPPGPPGPSGAVVPLALQNE 597 G G+PG GP GL G G P G PG KG PG PGP G V P E Sbjct: 1584 DPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGE 1635 Score = 149 bits (376), Expect = 9e-36 Identities = 81/170 (47%), Positives = 94/170 (55%), Gaps = 14/170 (8%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG-----ERG 497 G PG G G G G PG G +G+KGE+GE G GP G G GP GPPG + Sbjct: 2040 GIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEP 2099 Query: 498 GKGSKGSQGP---KGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGP------PGFQG 548 G G G QGP KG++G PG G QGP GD G PG G G PGP+G PG +G Sbjct: 2100 GPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERG 2159 Query: 549 LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598 + G G+PG+ GPRG PG G G PGP G PG GP+G P L+ EP Sbjct: 2160 MAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEP 2209 Score = 149 bits (375), Expect = 1e-35 Identities = 79/160 (49%), Positives = 88/160 (55%), Gaps = 14/160 (8%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 QGPPG +G+RG G G G+ G+ G G PG PG G G GP G PGERG +G Sbjct: 1286 QGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGP 1345 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL---PGPQGPPGFQGL-----QGTV 553 KG G G PG G GDPGP GPPG G PGP+GPPG G +G Sbjct: 1346 KGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDR 1405 Query: 554 GEPGVPGP------RGLPGLPGVPGMPGPKGPPGPPGPSG 587 GE G PGP G PGLPG+PG PGP+GP GPPG G Sbjct: 1406 GERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKG 1445 Score = 148 bits (373), Expect = 2e-35 Identities = 83/170 (48%), Positives = 90/170 (52%), Gaps = 21/170 (12%) Query: 443 GPPGPRGPRGDRGSQGPPGPT--GNKGQKGEKGEPGP-----------------PGPAGE 483 G PGP GP+G+ G G PG G G KGEKG PG PGP GE Sbjct: 2281 GLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGE 2340 Query: 484 RGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGK--PGPQGPSGDPGPPGPPGKEGLPGPQ 541 +G G AG PG+ G G KG+ GPKG +G PG PG GP G PG G G GLPG Sbjct: 2341 KGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAP 2400 Query: 542 GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 G GF G G GE G PGP G GL G PG G GP GPPGP G+V P Sbjct: 2401 GVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGP 2450 Score = 142 bits (359), Expect = 9e-34 Identities = 80/174 (45%), Positives = 96/174 (55%), Gaps = 31/174 (17%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGE-----RGPIGPAGPPGER 496 +G PGPRG +G+ G G PG + G+ G+KG PGP G G+ G GP GPPG + Sbjct: 2332 RGLPGPRGEKGEAGRAGEPG---DPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVK 2388 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGP------PGPPGKEGLPGP---------Q 541 G G G G G G PG+ GP+G G PGP GPPG+EG+PGP Sbjct: 2389 GDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSV 2448 Query: 542 GPPGFQGLQGTVGEPGV--PGPRGLPGLPGV------PGMPGPKGPPGPPGPSG 587 GPPG GL+G G+PGV PGPRG G PG+ PG GP+G GPPG G Sbjct: 2449 GPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRG 2502 Score = 140 bits (354), Expect = 3e-33 Identities = 82/209 (39%), Positives = 99/209 (47%), Gaps = 57/209 (27%) Query: 440 ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGE------------RGPI 487 ++ GPPGPRG +GD G +GP G G+KG +G+ G+PG G GE RG + Sbjct: 2524 VILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLL 2583 Query: 488 GPAGPPG------------------------------------ERGGKGS---KGSQGPK 508 GP G PG ERG KG+ G +G K Sbjct: 2584 GPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDK 2643 Query: 509 GSRGSPGKPGPQGPSGD------PGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G G PG+PG G G+ PG G PGKEGL GP+G GF G G G+ G G R Sbjct: 2644 GEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGER 2703 Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 G PG+ G PG G G GPPGP G+V P Sbjct: 2704 GTPGIGGFPGPSGNDGSAGPPGPPGSVGP 2732 Score = 139 bits (351), Expect = 7e-33 Identities = 77/179 (43%), Positives = 92/179 (51%), Gaps = 33/179 (18%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +G PG RG G RG +G PG G G++G +G GPPGP G+ G GPAG G+RG G Sbjct: 1718 KGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGL 1777 Query: 502 KGSQGPKGSRGSPGKPGPQ---GPSGDPGPPGPP---GKEGLPGPQGPPGFQGLQGTVGE 555 G G G G+ G GP G +GDPG G P G++GLPGP GPPG G G G+ Sbjct: 1778 DGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGK 1837 Query: 556 PGVPGPRGLPGLP---------------------------GVPGMPGPKGPPGPPGPSG 587 PG+ G G PG P G PG+ GP+GPPG PGP G Sbjct: 1838 PGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVG 1896 Score = 139 bits (350), Expect = 9e-33 Identities = 86/188 (45%), Positives = 91/188 (48%), Gaps = 24/188 (12%) Query: 441 LQGPPGPRGPRGDRGSQGPPG---------PTGNKGQKGEKGEPGPPG-----PAGERGP 486 LQGP GP GP G G GPPG P G G KGE GE GPPG P G G Sbjct: 2169 LQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGL 2228 Query: 487 IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSG---DPGPPGPPGKEGLPGPQGP 543 GP GP G G +GS G G G G PG PG G SG D G PG PG GLPGP GP Sbjct: 2229 PGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGP 2288 Query: 544 PGFQGLQGTVGEP--GVPGPRGLPGLPG-----VPGMPGPKGPPGPPGPSGAVVPLALQN 596 G G G G+ G+PG +G G PG + G PG KG G PGP G Sbjct: 2289 KGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAG 2348 Query: 597 EPTPAPED 604 EP ED Sbjct: 2349 EPGDPGED 2356 Score = 136 bits (342), Expect = 8e-32 Identities = 80/184 (43%), Positives = 93/184 (50%), Gaps = 20/184 (10%) Query: 441 LQGPPGPRGPRGDRGSQGPPG-------------PTGNKGQKGEKGEPGPPGPAGERGPI 487 L GPPG RG RG++G G G P G +G KG+ GE GP G G++GP Sbjct: 2494 LTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPR 2553 Query: 488 GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQ 547 G G PG+ KGSKG G KGS G PG G GP G PG G PG G PG G PG + Sbjct: 2554 GDNGDPGD---KGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIR 2610 Query: 548 GLQGTV---GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPED 604 G +G V G G+ G RG+ G G+ G G KG GPPG G EP P Sbjct: 2611 GEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEP-GVPGQ 2669 Query: 605 NGCP 608 +G P Sbjct: 2670 SGAP 2673 Score = 135 bits (341), Expect = 1e-31 Identities = 77/184 (41%), Positives = 92/184 (50%), Gaps = 23/184 (12%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG--- 498 QG PG G G+ G G PG G G+ G++G PG PG G GP+GP G PG G Sbjct: 2241 QGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQ 2300 Query: 499 --------KGSKGSQG-----------PKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPG 539 KG KG+ G KG RG PG G +G +G G PG PG++G G Sbjct: 2301 AVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKG 2360 Query: 540 PQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPT 599 GP GF+G G VG PG PGP G PG+ G G+PG G PG G G P +P Sbjct: 2361 APGPKGFKGDPG-VGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPG 2419 Query: 600 PAPE 603 P+ E Sbjct: 2420 PSGE 2423 Score = 135 bits (339), Expect = 2e-31 Identities = 73/154 (47%), Positives = 86/154 (55%), Gaps = 8/154 (5%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGP---AGERGPIGPAGPPGERGG 498 QG PG RGP G++G +GPPG G G G+ G GP GP AG+ G G G PG RG Sbjct: 1757 QGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGE 1816 Query: 499 KGSKGSQGPKGSRGSPG---KPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGE 555 +G G GP G G PG KPG G +G+PG PG G++G G G G +G G GE Sbjct: 1817 QGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGE 1876 Query: 556 PGVPGPRGLPGLPGVPGMPGPKGP--PGPPGPSG 587 G PG G G PG+PG GP G PG PG +G Sbjct: 1877 RGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTG 1910 Score = 134 bits (336), Expect = 4e-31 Identities = 85/220 (38%), Positives = 101/220 (45%), Gaps = 49/220 (22%) Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKG---------------------- 473 + F + G GP+G RG+ GS+G G G +G +GE G Sbjct: 1900 QGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREI 1959 Query: 474 -----------------EPGPPGPAGERGPIGPAGP---PGERGGKGSKGSQGPKGSRG- 512 GP G +GE+GP G GP PGERG KG +G GP+G G Sbjct: 1960 VETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGL 2019 Query: 513 SPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPG 572 + G+ GP GPSG G PG PG GLPG G G G G GE G G RG G G PG Sbjct: 2020 ALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPG 2079 Query: 573 MPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPPHWK 612 +PG GPPGPPGP +V +EP P PP K Sbjct: 2080 LPGTPGPPGPPGPKVSV------DEPGPGLSGEQGPPGLK 2113 Score = 134 bits (336), Expect = 4e-31 Identities = 83/177 (46%), Positives = 92/177 (51%), Gaps = 30/177 (16%) Query: 441 LQGPPGPRGPRGDRGSQGPP---GPTGNKGQKGEKGEPGP--PGPAGER----------- 484 L GPPG G G G GPP GP G G KG+KG+PG PGP GER Sbjct: 2426 LAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGR 2485 Query: 485 ----GPIGPAGPP---GERGGKGSKGSQGPKGSRGSP----GKPGPQGPSGDPGPPGPPG 533 GP G GPP GERG KG GS G KG +G G PGP+G GD G GP G Sbjct: 2486 PGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRG 2545 Query: 534 KEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGV---PGMPGPKGPPGPPGPSG 587 +G GP+G G G +G+ GEPG G GLPGL G+ G PG G PG PG G Sbjct: 2546 LDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPG 2602 Score = 133 bits (334), Expect = 7e-31 Identities = 73/153 (47%), Positives = 87/153 (56%), Gaps = 10/153 (6%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPA----GPPGERG 497 +G PG RG G G +GP G TG G +GE+GE G G AG +G G + GPPG RG Sbjct: 2474 RGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRG 2533 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP- 556 KG G +GP RG G GP+G +GDPG G G+ G G G PG +GL G G+P Sbjct: 2534 AKGDMGERGP---RGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPG 2590 Query: 557 --GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G+PG G PG GVPG+ G KG G GP G Sbjct: 2591 AAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRG 2623 Score = 132 bits (331), Expect = 2e-30 Identities = 70/138 (50%), Positives = 79/138 (57%), Gaps = 11/138 (7%) Query: 454 RGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGS 513 +G +G PG G +GQ G G+PG PG G GP GPPG KG +G G + G Sbjct: 1253 KGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGP---QGPPGSATAKGERGFPG---ADGR 1306 Query: 514 PGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGP----RGLPGLPG 569 PG PG G G PG PG G GLPGP+G PG +G +G GEPG PG G PGLPG Sbjct: 1307 PGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEG-PGLPG 1365 Query: 570 VPGMPGPKGPPGPPGPSG 587 G PGP GPPGP GP G Sbjct: 1366 RKGDPGPSGPPGPRGPLG 1383 Score = 127 bits (320), Expect = 3e-29 Identities = 80/185 (43%), Positives = 94/185 (50%), Gaps = 24/185 (12%) Query: 443 GPPGPRGPRGDRGSQG---PPGPTGNKGQKGEKGEPGPPGPAGERG------------PI 487 GPPGP G +GD G G PG G GQ G +GE G PGP+GERG P+ Sbjct: 2380 GPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPL 2439 Query: 488 GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQ 547 GP GPPG G G+ G +G KG G G PGP+G G+PG G G+ G GP+G G Sbjct: 2440 GPPGPPGSVGPPGASGLKGDKGDPG-VGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPP 2498 Query: 548 GLQGTVGEPGVPGPRGLPGLPG----VPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPE 603 G +G GE G G GL G G + G PGP+G G G G P L + P Sbjct: 2499 GSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERG---PRGLDGDKGPR-G 2554 Query: 604 DNGCP 608 DNG P Sbjct: 2555 DNGDP 2559 Score = 127 bits (318), Expect = 5e-29 Identities = 83/219 (37%), Positives = 94/219 (42%), Gaps = 62/219 (28%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGE---------------RG 485 L G PG GP G G+ G G G G G +GE G PGP+G G Sbjct: 1783 LDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNG 1842 Query: 486 PIGPAGPPGERGGKGSKGS---------QGPKGSRGSPGKPGPQGPSGDPGPPGPPGK-- 534 G G PGE G KG KG GPKG RG+PG GPQGP G PGP GPPG+ Sbjct: 1843 KNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGF 1902 Query: 535 EGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPG-VPGMP------------------- 574 G+PG GP G +G G+ GE G+PG RGL G PG VP + Sbjct: 1903 PGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVET 1962 Query: 575 ----------------GPKGPPGPPGPSGAVVPLALQNE 597 GPKG G GP G P+ E Sbjct: 1963 WDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGE 2001 Score = 102 bits (255), Expect = 1e-21 Identities = 49/100 (49%), Positives = 54/100 (54%) Query: 489 PAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG 548 P G GE G G +G GP G G PG+ G GP G PG G+ G PG G PG G Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPG 1311 Query: 549 LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588 G G PG PG +G PGLPG G PG +GP GP G GA Sbjct: 1312 RAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGA 1351 Score = 98.6 bits (244), Expect = 2e-20 Identities = 48/98 (48%), Positives = 55/98 (56%), Gaps = 6/98 (6%) Query: 507 PKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF------QGLQGTVGEPGVPG 560 PKG +G PG+ G +G G PG PG PG+ G PGPQGPPG +G G G PG PG Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPG 1311 Query: 561 PRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598 G PG PG PG+ G G PGP G G P + EP Sbjct: 1312 RAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEP 1349 Score = 33.1 bits (74), Expect = 0.96 Identities = 17/41 (41%), Positives = 19/41 (46%) Query: 561 PRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601 P+G G PG G+ G GPPG PG G Q P A Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSA 1292 >gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] Length = 680 Score = 162 bits (410), Expect = 1e-39 Identities = 92/186 (49%), Positives = 103/186 (55%), Gaps = 16/186 (8%) Query: 441 LQGPPGPRGPRGDRGSQGPPG---PTGNKGQKGEKGEPGP---PGPAGERGPIGPAGPPG 494 L G PG +G +G G G PG P GN G +G KG PG PGP GE GP GPAG PG Sbjct: 315 LPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPG 374 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPG---KEGLPGPQGPPGFQGLQG 551 +G +GS GS G G G PG GP+G G PGP G PG GLPGP GP G +G+ G Sbjct: 375 AKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPG 434 Query: 552 TVGE------PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG-AVVPLALQNEPTPAPED 604 GE PG+PG RG G PG+PG PG KG PG PGP G A + N PT P Sbjct: 435 HNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGP 494 Query: 605 NGCPPH 610 G H Sbjct: 495 PGPRGH 500 Score = 158 bits (399), Expect = 2e-38 Identities = 82/160 (51%), Positives = 91/160 (56%), Gaps = 19/160 (11%) Query: 443 GPPGPRGPRGDRGSQGPPGPTG--NKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 GPPGP GPRG G GPPG G + G +GE G PGPPGP+ +G G PG G G Sbjct: 63 GPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSA----VGKPGVPGLPGKPG 118 Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP-----PGKEGLPGPQGPPGFQGLQGTVGE 555 +G GPKG G G PGP+GP G PG PGP PGK G GP G PG +G G G Sbjct: 119 ERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGA 178 Query: 556 PGVPGPR--------GLPGLPGVPGMPGPKGPPGPPGPSG 587 PGVPG G PG PG G+PGP+GP GP GP G Sbjct: 179 PGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPG 218 Score = 155 bits (393), Expect = 1e-37 Identities = 79/147 (53%), Positives = 86/147 (58%), Gaps = 8/147 (5%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAG---PPGERGGK 499 G PG +G RG GS G PG G G G KG PG PGP G+ G GP G P G G K Sbjct: 371 GYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAK 430 Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPG-----FQGLQGTVG 554 G G G G RG+PG PG +GP G PG PG PG +G PG GPPG +GL G G Sbjct: 431 GMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTG 490 Query: 555 EPGVPGPRGLPGLPGVPGMPGPKGPPG 581 PG PGPRG G PG+PG PGP GPPG Sbjct: 491 PPGPPGPRGHSGEPGLPGPPGPPGPPG 517 Score = 152 bits (383), Expect = 1e-36 Identities = 85/174 (48%), Positives = 94/174 (54%), Gaps = 17/174 (9%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKG-----EPGPPGPAGERGPIGPAGPPG-- 494 QGP G GPRG G +G PG G GQKGE G PG G G +GP GP+GPPG Sbjct: 161 QGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVG 220 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL--PGPQGPPGFQGLQGT 552 +RG G G G KG RG PG+ GP GP G GPPG G EG+ PG G PG G+ GT Sbjct: 221 KRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGT 280 Query: 553 VGEPGVPGPR--------GLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598 G PG PG G PGLPG+ G GP G PG PG G P L +P Sbjct: 281 KGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKP 334 Score = 147 bits (371), Expect = 3e-35 Identities = 86/217 (39%), Positives = 103/217 (47%), Gaps = 61/217 (28%) Query: 443 GPPGPRGPRGDRGSQG-----------------------------PPGPTGN-------- 465 GPPGP+GP G+RG +G PPGP G Sbjct: 247 GPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGL 306 Query: 466 KGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD 525 KG++G G PG PG GE+GP G G PG G G+ G QGPKG GS G PGP+G +G Sbjct: 307 KGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGP 366 Query: 526 PGP---PGPPGKEGLPGPQGPPGFQG---LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGP 579 GP PG G+ G PG G PG+ G L G G PG+PGP+G PG+ G PG+PGP GP Sbjct: 367 AGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGP 426 Query: 580 ------------------PGPPGPSGAVVPLALQNEP 598 PG PG G + P + P Sbjct: 427 AGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFP 463 Score = 144 bits (364), Expect = 2e-34 Identities = 87/202 (43%), Positives = 104/202 (51%), Gaps = 42/202 (20%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP-----PGPAGERGPIGPAGP--- 492 L G PG RGP G +G GP G G +G G G PGP PG G++GP G GP Sbjct: 113 LPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGF 172 Query: 493 PGERGGKGSKGSQGPKGSR--GSPGK------PGPQGPSGDPGPP--------GPPGKEG 536 PGE+G G G G KG G+PG+ PGPQGP+G GPP G PG+ G Sbjct: 173 PGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPG 232 Query: 537 L---------------PGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPG 581 + PGPQGPPG +G +G +G+PG G G PG+PG G+PG G G Sbjct: 233 IKGDRGFPGEMGPIGPPGPQGPPGERGPEG-IGKPGAAGAPGQPGIPGTKGLPGAPGIAG 291 Query: 582 PPGPSGAVVP--LALQNEPTPA 601 PPGP G P L+ E PA Sbjct: 292 PPGPPGFGKPGLPGLKGERGPA 313 Score = 109 bits (273), Expect = 8e-24 Identities = 73/171 (42%), Positives = 84/171 (49%), Gaps = 27/171 (15%) Query: 442 QGPPGPRGPRGDRGSQG-PPGPTGNKG--QKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498 Q P G +GP + +Q P +KG +GE+G PGPPGPA Sbjct: 26 QMPTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPA----------------- 68 Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV 558 G +G GP G G PG P G G+PG PGPPG P G PG GL G GE G Sbjct: 69 -GPRGHPGPSGPPGKPGYGSP-GLQGEPGLPGPPG----PSAVGKPGVPGLPGKPGERGP 122 Query: 559 PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP-LALQNEPTPAPEDNGCP 608 GP+G G G+PG GP GPPG PGP+G VP Q PT AP G P Sbjct: 123 YGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFP 173 Score = 47.4 bits (111), Expect = 5e-05 Identities = 33/85 (38%), Positives = 40/85 (47%), Gaps = 17/85 (20%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +G GP GP GPPGP G+ G+ G G PGPPGP G+ + P G Sbjct: 483 KGLNGPTGP------PGPPGPRGHSGEPGLPGPPGPPGPPGQ--AVMPEG--------FI 526 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDP 526 K Q P S G+P QG +G P Sbjct: 527 KAGQRPSLS-GTPLVSANQGVTGMP 550 >gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens] Length = 540 Score = 162 bits (410), Expect = 1e-39 Identities = 87/196 (44%), Positives = 100/196 (51%), Gaps = 38/196 (19%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP------------IG 488 L G PG GP+G++G+ G GP G++GQ G G PGPPGP G RGP G Sbjct: 152 LDGKPGLPGPKGEKGAPGDFGPRGDQGQDGAAGPPGPPGPPGARGPPGDTGKDGPRGAQG 211 Query: 489 PAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG 548 PAGP GE G G G +GP G +G PG PG +G G P PGPPG +G PG GP G G Sbjct: 212 PAGPKGEPGQDGEMGPKGPPGPKGEPGVPGKKGDDGTPSQPGPPGPKGEPGSMGPRGENG 271 Query: 549 LQGTVGEPGVP---------GPRGLPGLPG-----------------VPGMPGPKGPPGP 582 + G G G P GPRG PGL G + G PGP+GPPGP Sbjct: 272 VDGAPGPKGEPGHRGTDGAAGPRGAPGLKGEQGDTVVIDYDGRILDALKGPPGPQGPPGP 331 Query: 583 PGPSGAVVPLALQNEP 598 PG GA L L P Sbjct: 332 PGIPGAKGELGLPGAP 347 Score = 152 bits (383), Expect = 1e-36 Identities = 84/177 (47%), Positives = 95/177 (53%), Gaps = 22/177 (12%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGE---KGEPGPPGPAGERGP---IGPAGPPGER 496 GPPG RG G RG GPPG +G G G G+PG PGP GE+G GP G G+ Sbjct: 121 GPPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDGKPGLPGPKGEKGAPGDFGPRGDQGQD 180 Query: 497 GGKGSKGSQGPKGSRGSP---GKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553 G G G GP G+RG P GK GP+G G GP G PG++G GP+GPP G Sbjct: 181 GAAGPPGPPGPPGARGPPGDTGKDGPRGAQGPAGPKGEPGQDGEMGPKGPP------GPK 234 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPPH 610 GEPGVPG +G G P PG PGPKG PG GP G +N AP G P H Sbjct: 235 GEPGVPGKKGDDGTPSQPGPPGPKGEPGSMGPRG-------ENGVDGAPGPKGEPGH 284 Score = 145 bits (366), Expect = 1e-34 Identities = 84/209 (40%), Positives = 97/209 (46%), Gaps = 53/209 (25%) Query: 442 QGPPGPRGPRGDRGSQG---PPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498 +G PG GPRGD+G G PPGP G G +G G+ G GP G +GP GP G PG+ G Sbjct: 165 KGAPGDFGPRGDQGQDGAAGPPGPPGPPGARGPPGDTGKDGPRGAQGPAGPKGEPGQDGE 224 Query: 499 KGSKGSQGPKGSRGSPGK---------PGPQGPSGDPGPPGPPGKEGL---PGPQGPPGF 546 G KG GPKG G PGK PGP GP G+PG GP G+ G+ PGP+G PG Sbjct: 225 MGPKGPPGPKGEPGVPGKKGDDGTPSQPGPPGPKGEPGSMGPRGENGVDGAPGPKGEPGH 284 Query: 547 QGLQGTVGEPGVPG-----------------------------PRGLP---------GLP 568 +G G G G PG P G P GLP Sbjct: 285 RGTDGAAGPRGAPGLKGEQGDTVVIDYDGRILDALKGPPGPQGPPGPPGIPGAKGELGLP 344 Query: 569 GVPGMPGPKGPPGPPGPSGAVVPLALQNE 597 G PG+ G KGP G G G P L+ E Sbjct: 345 GAPGIDGEKGPKGQKGDPGEPGPAGLKGE 373 Score = 143 bits (360), Expect = 7e-34 Identities = 87/222 (39%), Positives = 102/222 (45%), Gaps = 58/222 (26%) Query: 441 LQGPPGPRGP---------RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG--------- 482 L+GPPGP+GP +G+ G G PG G KG KG+KG+PG PGPAG Sbjct: 319 LKGPPGPQGPPGPPGIPGAKGELGLPGAPGIDGEKGPKGQKGDPGEPGPAGLKGEAGEMG 378 Query: 483 -------------------------------ERGPIGPAGPPGERGGKGSKGSQGPKGSR 511 E GP GP GPPG G +G +G +G G++ Sbjct: 379 LSGLPGADGLKGEKGESASDSLQESLAQLIVEPGPPGPPGPPGPMGLQGIQGPKGLDGAK 438 Query: 512 GSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGP------PGFQGLQGTVGEPGVPGPRGLP 565 G G G +GPSG PGP GPPG GLPG +G PG G G GE G RG Sbjct: 439 GEKGASGERGPSGLPGPVGPPGLIGLPGTKGEKGRPGEPGLDGFPGPRGEKGDRSERGEK 498 Query: 566 GLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGC 607 G GVPG G KG G PGP G P + + P P GC Sbjct: 499 GERGVPGRKGVKGQKGEPGPPGLDQPCPVGPDGLPVP---GC 537 Score = 138 bits (348), Expect = 2e-32 Identities = 80/173 (46%), Positives = 86/173 (49%), Gaps = 31/173 (17%) Query: 440 ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499 IL GP GP QGPPGP G G KGE G PG PG GE+GP G G PGE G Sbjct: 315 ILDALKGPPGP------QGPPGPPGIPGAKGELGLPGAPGIDGEKGPKGQKGDPGEPGPA 368 Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGD-------------------PGPPGPPGKEGLPGP 540 G KG G G G PG G +G G+ PGPPGPPG GL G Sbjct: 369 GLKGEAGEMGLSGLPGADGLKGEKGESASDSLQESLAQLIVEPGPPGPPGPPGPMGLQGI 428 Query: 541 QGPPGFQGLQGTV------GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 QGP G G +G G G+PGP G PGL G+PG G KG PG PG G Sbjct: 429 QGPKGLDGAKGEKGASGERGPSGLPGPVGPPGLIGLPGTKGEKGRPGEPGLDG 481 Score = 132 bits (333), Expect = 9e-31 Identities = 70/161 (43%), Positives = 83/161 (51%), Gaps = 9/161 (5%) Query: 459 PPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPG 518 PPGP G +G+ G +G+PGPPG +G G GP G G+ G GPKG +G+PG G Sbjct: 119 PPGPPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDGK------PGLPGPKGEKGAPGDFG 172 Query: 519 PQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGV---PGMPG 575 P+G G G GPPG G PG +GPPG G G G G GP+G PG G G PG Sbjct: 173 PRGDQGQDGAAGPPGPPGPPGARGPPGDTGKDGPRGAQGPAGPKGEPGQDGEMGPKGPPG 232 Query: 576 PKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPPHWKNFTD 616 PKG PG PG G + P P E P +N D Sbjct: 233 PKGEPGVPGKKGDDGTPSQPGPPGPKGEPGSMGPRGENGVD 273 Score = 73.2 bits (178), Expect = 8e-13 Identities = 39/87 (44%), Positives = 46/87 (52%), Gaps = 15/87 (17%) Query: 520 QGPSGDPGPPGPPGKEGLPGPQGPP---------GFQGLQGTVGEPGVPGPRGLPGLP-- 568 + PS PPGPPG+ G PG +G P G+ G G G+PG+PGP+G G P Sbjct: 111 EAPSECVCPPGPPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDGKPGLPGPKGEKGAPGD 170 Query: 569 ----GVPGMPGPKGPPGPPGPSGAVVP 591 G G G GPPGPPGP GA P Sbjct: 171 FGPRGDQGQDGAAGPPGPPGPPGARGP 197 >gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo sapiens] Length = 1650 Score = 162 bits (409), Expect = 1e-39 Identities = 89/188 (47%), Positives = 99/188 (52%), Gaps = 30/188 (15%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPG---PAGERGPIGPAGPPGERG 497 L G PG +GP+G G G PG +G KG +G G+ GP G P G RG GP G G+ G Sbjct: 714 LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG 773 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGP---PGPPGKEGLP---------------G 539 KG+ G GP G G G PGPQGP+G PGP PGPPGK+GLP G Sbjct: 774 AKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTG 833 Query: 540 PQGPPGFQGLQGTVGE---------PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVV 590 P GPPG G QG GE PG PGP G GLPG G G KG PGPPG G Sbjct: 834 PPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDG 893 Query: 591 PLALQNEP 598 P L+ P Sbjct: 894 PAGLRGFP 901 Score = 160 bits (404), Expect = 5e-39 Identities = 83/158 (52%), Positives = 97/158 (61%), Gaps = 9/158 (5%) Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGP 492 + F L G PG +G RGD G+QG PGP G G++G+ GE GP PG +G RG +GP GP Sbjct: 472 RGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGP 531 Query: 493 PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQ---GPPGFQGL 549 PG G G +G GP+G +GS G PQG G PG G PG +GLPGPQ GP G +G Sbjct: 532 PGIPGPPGVRGMDGPQGPKGSLG---PQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 588 Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 QG G PG+PG G PG PG G PG KG GP GP G Sbjct: 589 QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQG 626 Score = 159 bits (403), Expect = 7e-39 Identities = 82/164 (50%), Positives = 96/164 (58%), Gaps = 18/164 (10%) Query: 442 QGPPGPRGPRGDRGSQGPPGP------TGNKGQKGE---KGEPGPPGPAGERGPIGPAGP 492 +G PGP+GP G G +GPPGP G+ GQ+GE +G+ GPPGP G GP G AG Sbjct: 790 RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGE 849 Query: 493 PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552 G G +G G GP G +G PG G +G GDPGPPG PGK+G G +G PG +GL GT Sbjct: 850 TGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGT 909 Query: 553 VGEPGV---------PGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G PG+ PGP G PG G G GP GPPG PGP G Sbjct: 910 AGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQG 953 Score = 159 bits (402), Expect = 9e-39 Identities = 84/182 (46%), Positives = 96/182 (52%), Gaps = 36/182 (19%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP---------- 492 GP G RGP G RG +GP G TG G KG G GP GP GERG GP GP Sbjct: 749 GPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPP 808 Query: 493 -----------PGERGGKGSKGSQGPKGS------RGSPGKPGPQGPSGDPGPPGPPGKE 535 PG+RG G +G GP G +G+ G+ GP G G PGPPGPPG++ Sbjct: 809 GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ 868 Query: 536 GLP---------GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPS 586 GLP G GPPG G G G G PG RGLPG G PG+ G +GP GPPGP+ Sbjct: 869 GLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPA 928 Query: 587 GA 588 G+ Sbjct: 929 GS 930 Score = 159 bits (402), Expect = 9e-39 Identities = 84/182 (46%), Positives = 99/182 (54%), Gaps = 30/182 (16%) Query: 443 GPPGPRGPRGDRGSQGPPGPTG---------------------NKGQKGEKGEPGPPGPA 481 GPPGP+GP GD G +G PGP G ++G+ GE G+PG PGP Sbjct: 1163 GPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPT 1222 Query: 482 GERGPIGP------AGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKE 535 GE GP GP AG PG G +G KG++G G+ G+PGK GP GP+G G PGP G Sbjct: 1223 GENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLR 1282 Query: 536 GLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQ 595 GLPG G QG G G+ G PGP G PGLPG+ G G KG G PG G + P Q Sbjct: 1283 GLPGSVGQ---QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQ 1339 Query: 596 NE 597 E Sbjct: 1340 GE 1341 Score = 158 bits (399), Expect = 2e-38 Identities = 82/148 (55%), Positives = 88/148 (59%), Gaps = 12/148 (8%) Query: 443 GPPGPRGPRGDRGS---QGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499 GPPGPRGP G G+ QGPPG GN G GEKGEPG G G +G G GP GERG K Sbjct: 1094 GPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEK 1153 Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559 G G G PG PGP+GP+GD GP G PG G PG GPPG +G G G+ G Sbjct: 1154 GESGQP------GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG-EG--GPRGQDGAK 1204 Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G RG G PG PG PGP G GPPGP G Sbjct: 1205 GDRGEDGEPGQPGSPGPTGENGPPGPLG 1232 Score = 157 bits (397), Expect = 3e-38 Identities = 86/167 (51%), Positives = 93/167 (55%), Gaps = 18/167 (10%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---PAGPPG----- 494 G GP GP G G QGPPG G KG GEKG GP G G +GP+G PAGPPG Sbjct: 938 GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGED 997 Query: 495 ----ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQ 550 E G G KG++G KG G PG PGP GP G PG G G+ G GPQG G +G + Sbjct: 998 GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1057 Query: 551 GTVGEPGVPGPRGLPGLPGVPGMP------GPKGPPGPPGPSGAVVP 591 GT G G PGP GL GLPG G GP GPPGPPGP G P Sbjct: 1058 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGP 1104 Score = 157 bits (396), Expect = 4e-38 Identities = 81/161 (50%), Positives = 94/161 (58%), Gaps = 3/161 (1%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GPPG G +G G G PG G +G KG G PG PG +GE+G G +G G RG +G Sbjct: 698 GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 757 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G +G +G RG+ GK G +G SG GP GPPG+ GLPGPQGP GF G + G PG PG Sbjct: 758 GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK---GPPGPPGKD 814 Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPE 603 GLPG PG G G +G GPPGP G V P E P E Sbjct: 815 GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 855 Score = 157 bits (396), Expect = 4e-38 Identities = 88/206 (42%), Positives = 94/206 (45%), Gaps = 45/206 (21%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GPPG G GD+G G PG G KG KGE G PGPPGP G G G AG GE G +G + Sbjct: 989 GPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQ 1048 Query: 503 GS------------------------QGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLP 538 G GP G +G G GP GP G PGP GP G G Sbjct: 1049 GHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGAD 1108 Query: 539 GPQGP---------------PGFQGLQGTVGEPGVPGPR------GLPGLPGVPGMPGPK 577 GPQGP PG G G GEPGV GPR G G PG PG PGPK Sbjct: 1109 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK 1168 Query: 578 GPPGPPGPSGAVVPLALQNEPTPAPE 603 GP G GP G P+ +P P E Sbjct: 1169 GPTGDDGPKGNPGPVGFPGDPGPPGE 1194 Score = 154 bits (390), Expect = 2e-37 Identities = 82/158 (51%), Positives = 92/158 (58%), Gaps = 15/158 (9%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE---PGPPGPAGERGPIGPAGPPGERGG 498 +G PG G +GDRG G PG G KG +G+ G PGPPG GERG G GP G G Sbjct: 460 RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 519 Query: 499 KGSKGSQGPKGSRGSPGKP------GPQGPSGDPGP---PGPPGKEGLPGPQGPPGFQGL 549 G +G GPKG G PG P GPQGP G GP PGPPG++G PG QG P G Sbjct: 520 SGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP---GP 576 Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 QG +G G GP+G PGLPG+PG GP G PG GP G Sbjct: 577 QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPG 614 Score = 153 bits (386), Expect = 6e-37 Identities = 84/190 (44%), Positives = 98/190 (51%), Gaps = 45/190 (23%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKG------QKGEKGEPGPPGPAGERGPIGPAGPPGE 495 QG G GP G+RG GPPGP G +G ++G KG+PGPPG G+ GP G G PGE Sbjct: 844 QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE 903 Query: 496 RG------GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGL 549 RG G G KG++GP G G G PG +G +G GP GPPG+ PGPQGPPG G Sbjct: 904 RGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGR---PGPQGPPGAAGE 960 Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPP----------------------------- 580 +G GE G GP G G+ G G+PGP GPP Sbjct: 961 KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 1020 Query: 581 -GPPGPSGAV 589 GPPGP G V Sbjct: 1021 PGPPGPIGPV 1030 Score = 152 bits (383), Expect = 1e-36 Identities = 78/172 (45%), Positives = 95/172 (55%), Gaps = 8/172 (4%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI---GPAGPPGERG 497 +QG PG +GPRG+RG +G G G G G KG G GP G GP+ G GPPGE G Sbjct: 1137 IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGG 1196 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557 +G G++G +G G PG+PG GP+G+ GPPGP GK GP G PG +G QG G G Sbjct: 1197 PRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR---GPAGSPGSEGRQGGKGAKG 1253 Query: 558 VPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609 PG G PG G G GP G PGP G G +P ++ + P PP Sbjct: 1254 DPGAIGAPGKTGPVGPAGPAGKPGPDGLRG--LPGSVGQQGRPGATGQAGPP 1303 Score = 151 bits (382), Expect = 2e-36 Identities = 77/159 (48%), Positives = 88/159 (55%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G GP GP G RG G PG G +G KG KG+PG G G+ GP+GPAGP G+ G G + Sbjct: 1223 GENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLR 1282 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G G G +G PG G GP G GPPG PG G G +G G GL G +G PG G + Sbjct: 1283 GLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEK 1342 Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601 G GLPG G PG KG G PG SG + P P PA Sbjct: 1343 GDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPA 1381 Score = 149 bits (376), Expect = 9e-36 Identities = 82/171 (47%), Positives = 91/171 (53%), Gaps = 24/171 (14%) Query: 441 LQGPPGPRGPRGDRGSQGP---PGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERG 497 L GPPG G RG G+ G PG G KG +G G PG PG G RG G G PG G Sbjct: 441 LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 500 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQ---GPSGDPGPPGPPGKEGLPGPQGP---------PG 545 G +G G G RG PG+ GP+ GP G PG PGPPG G+ GPQGP PG Sbjct: 501 EDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG 560 Query: 546 FQGLQGTVGEPGVPGPRGL---------PGLPGVPGMPGPKGPPGPPGPSG 587 G QGT G G+PGP+G G PG+PGMPG GPPG PG G Sbjct: 561 PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEG 611 Score = 147 bits (372), Expect = 3e-35 Identities = 81/189 (42%), Positives = 97/189 (51%), Gaps = 22/189 (11%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG------PIGPAGPPGER 496 G PG RGP+G G++G G G G G G G PGP+GE+G P+GP GPPG R Sbjct: 1040 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1099 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G G G+ GP+G G G GP G G+PG G PG +G PG +GP G +G +G G+P Sbjct: 1100 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP 1159 Query: 557 GVP------------GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP----TP 600 G P GP+G PG G PG PGP G GP G GA EP +P Sbjct: 1160 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSP 1219 Query: 601 APEDNGCPP 609 P PP Sbjct: 1220 GPTGENGPP 1228 Score = 145 bits (367), Expect = 1e-34 Identities = 78/160 (48%), Positives = 86/160 (53%), Gaps = 7/160 (4%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G GP GP G G GP G G G G++G PG G AG GP+GP G PG RG G+K Sbjct: 1262 GKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAK 1321 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G +G G G G PG QG GD G PGP G G G G PG G G G PG+PGP Sbjct: 1322 GEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPA 1381 Query: 563 GLPGLPGVPGMPGPK------GPPGPPGPSGAVV-PLALQ 595 G G G G GPK GPPG PGP G V+ PL +Q Sbjct: 1382 GPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQ 1421 Score = 144 bits (363), Expect = 3e-34 Identities = 81/170 (47%), Positives = 88/170 (51%), Gaps = 10/170 (5%) Query: 448 RGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGP 507 RGP G G G PGP G G G KGE G GP G RGP G GPPG+ G +G G+ G Sbjct: 400 RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 459 Query: 508 KGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGL 567 +G G PG G +G G PG PG G G G QG PG G G G+ G GPRGLPG Sbjct: 460 RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 519 Query: 568 PGVPGMPGPKGPPGPP---------GPSGAVVPLALQNEPTPAPEDNGCP 608 G G+ GPKGPPG P GP G L Q EP P P G P Sbjct: 520 SGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP-PGQQGTP 568 Score = 142 bits (357), Expect = 1e-33 Identities = 77/160 (48%), Positives = 89/160 (55%), Gaps = 3/160 (1%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 QG PGP G +G G+QG PGP G G GEKG G PG G G GP G PG+ G G+ Sbjct: 556 QGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGT 615 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG---LQGTVGEPGV 558 KG+QGP G +G G PGP+G G G G G +G G G PGF+G ++G GE GV Sbjct: 616 KGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV 675 Query: 559 PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598 PG RG G G G GP G PGPPG G L + P Sbjct: 676 PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLP 715 Score = 140 bits (354), Expect = 3e-33 Identities = 75/166 (45%), Positives = 87/166 (52%), Gaps = 9/166 (5%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 ++G GP+GP+G G QG PGP G +G G +G PGP G G G GP G PG G G Sbjct: 540 VRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 599 Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP- 559 S G G G G PG G QGPSG GP G PG G+ G G G +G +G GE G P Sbjct: 600 SDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPG 659 Query: 560 --------GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNE 597 G RG G+PG G GP+GP G GP+G P L E Sbjct: 660 FKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGE 705 Score = 140 bits (353), Expect = 4e-33 Identities = 78/179 (43%), Positives = 97/179 (54%), Gaps = 11/179 (6%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGE---KGEPGPPGPAGERGPIGPAGPPGERGGK 499 G GP+GPRG +G GPPG G +G+ G +G PG PG G+RG G G PGE+G + Sbjct: 428 GDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHR 487 Query: 500 GSKGSQG------PKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553 G G+QG G RG G+ GP+G G+ GP G G +G PG GPPG +G+ G Sbjct: 488 GDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQ 547 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP--TPAPEDNGCPPH 610 G G GP+G PG PG G PG +G PGP G G Q +P P +G P H Sbjct: 548 GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 606 Score = 139 bits (350), Expect = 9e-33 Identities = 85/197 (43%), Positives = 90/197 (45%), Gaps = 51/197 (25%) Query: 442 QGPPGPRGPRG---DRGSQGPPGPTGNKGQKGEK-------------------------- 472 QGP GP+GP G RG +G G G KG KGEK Sbjct: 619 QGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGS 678 Query: 473 -GEPGPPGPAGERGPIGPAGPPGERGGKGS---------KGSQGPKGSRGSPGKP----- 517 GE GP GP G GP G GPPG G KG G QGPKGS G PG P Sbjct: 679 RGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGE 738 Query: 518 -------GPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGV 570 G GP G+ GP GP G+ G G G G +G G G G PG RGLPG G Sbjct: 739 KGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGP 798 Query: 571 PGMPGPKGPPGPPGPSG 587 G PGPKGPPGPPG G Sbjct: 799 NGFPGPKGPPGPPGKDG 815 Score = 139 bits (349), Expect = 1e-32 Identities = 81/181 (44%), Positives = 92/181 (50%), Gaps = 18/181 (9%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG---PPGPAGERGPIGPAGP---PG 494 L GP G GP G++G QG PG G G G G PG PPG G +GP GP GP PG Sbjct: 573 LPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPG 632 Query: 495 ERGGKGS------KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG 548 RG KG KG +G KG G PG G G GD G G PG G GP+GP G G Sbjct: 633 PRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTG 692 Query: 549 LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGP------PGPPGPSGAVVPLALQNEPTPAP 602 G G PG+ G +G G+PG+PG PG +GP PG PG SG L + P Sbjct: 693 PTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG 752 Query: 603 E 603 E Sbjct: 753 E 753 Score = 137 bits (346), Expect = 3e-32 Identities = 76/152 (50%), Positives = 81/152 (53%), Gaps = 12/152 (7%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG---ERGPIG---PAGPPGER 496 G GP G RG G +G PG G G KG +G GPPGPAG ERG G P GPPG Sbjct: 890 GKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGR- 948 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G QGP G+ G G PG +GP G G G G GLPGP GPPG G G GE Sbjct: 949 -----PGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 1003 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588 G PG +G G G G PGP GP GP G GA Sbjct: 1004 GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1035 Score = 136 bits (342), Expect = 8e-32 Identities = 76/170 (44%), Positives = 91/170 (53%), Gaps = 12/170 (7%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGE---------KGEPGPPGPAGERGPIGPAG 491 L+GPPGP G G G G PG G KG+ G+ +G GPPG AG RG G G Sbjct: 399 LRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADG 458 Query: 492 PPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQG 551 G G G KG +G G G PG+ G +G +G G PGPPG++G G G G +GL G Sbjct: 459 ARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPG 518 Query: 552 TVGEPGVPGPRGLPGLPGVP---GMPGPKGPPGPPGPSGAVVPLALQNEP 598 G G+ GP+G PG+PG P GM GP+GP G GP G P Q P Sbjct: 519 ESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTP 568 Score = 136 bits (342), Expect = 8e-32 Identities = 81/191 (42%), Positives = 94/191 (49%), Gaps = 21/191 (10%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 L G PG GP G G +GPPG GN+G G +G G PGP G +G G G G +G KG Sbjct: 594 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 653 Query: 501 S------KGSQGPKGSRGSPGKPG------PQGPS------GDPGPP---GPPGKEGLPG 539 KG G KG RG G PG P+GP GDPGPP G GK G+PG Sbjct: 654 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 713 Query: 540 PQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPT 599 G PG QG +G++G PG PG G G G+ G GP+G GP GP G P + Sbjct: 714 LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG 773 Query: 600 PAPEDNGCPPH 610 G PH Sbjct: 774 AKGTSGGDGPH 784 Score = 131 bits (330), Expect = 2e-30 Identities = 82/216 (37%), Positives = 94/216 (43%), Gaps = 58/216 (26%) Query: 440 ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGE---- 495 +++GPPGP GP G GPPG GN G G+ GE GPPG AG G G GPPG Sbjct: 310 LVEGPPGPEGPAG---LIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLML 366 Query: 496 ---------------------------------RGGKGSKGSQGPKGSRGSPGKPGPQGP 522 RG G G G G G PG PG +G Sbjct: 367 PFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGE 426 Query: 523 SGDPGPPGPPGKEGLPGP------QGPPGFQGLQGTVGEPGVPGPRGLPGLPGVP----- 571 SGD GP GP G +GL GP +G G G +G G+PGV G RG GLPG+P Sbjct: 427 SGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGH 486 Query: 572 -------GMPGPKGPPGPPGPSGAVVPLALQNEPTP 600 G+PGP G G G G + P L E P Sbjct: 487 RGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGP 522 Score = 125 bits (314), Expect = 1e-28 Identities = 70/145 (48%), Positives = 80/145 (55%), Gaps = 9/145 (6%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 L G G +G G G GPPGP G G G +G+ G G G G IG GPPGE+G KG Sbjct: 1284 LPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKG 1343 Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPG 560 +G GP+GS G G+ G G SG GP GPPG LPGP GP G +G G PG G Sbjct: 1344 DRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPG---LPGPAGPKGAKGATG----PG--G 1394 Query: 561 PRGLPGLPGVPGMPGPKGPPGPPGP 585 P+G G+ G PG PGP G P P Sbjct: 1395 PKGEKGVQGPPGHPGPPGEVIQPLP 1419 Score = 107 bits (268), Expect = 3e-23 Identities = 69/171 (40%), Positives = 75/171 (43%), Gaps = 44/171 (25%) Query: 461 GPTGNKGQKGE----------KGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGS 510 GP G KG+KGE +G PGP GPAG GP G G PG G G +G G G Sbjct: 291 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 350 Query: 511 RGSPGKPGPQGPS-----------GDP-----------------------GPPGPPGKEG 536 GS G PGP G S GD GPPGP G G Sbjct: 351 PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTG 410 Query: 537 LPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 PGP G PG GL+G G+ G GPRG GL G PG G +G G G G Sbjct: 411 RPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARG 461 Score = 92.0 bits (227), Expect = 2e-18 Identities = 62/170 (36%), Positives = 68/170 (40%), Gaps = 58/170 (34%) Query: 464 GNKGQKGEKGEPG--PPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQG 521 G +G KGEKGEP PG E GPPG +GP G G PG G G Sbjct: 291 GPRGLKGEKGEPAVLEPGMLVE-------GPPGP---------EGPAGLIGPPGIQGNPG 334 Query: 522 PSGDPGPPGPPGKEGLPGPQGPPG------------------------------------ 545 P GDPG GPPG+ GLPG G PG Sbjct: 335 PVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQ 394 Query: 546 ----FQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 +G G +G G PGP G PG PG+ G G GP GP GP G P Sbjct: 395 ARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGP 444 Score = 72.8 bits (177), Expect = 1e-12 Identities = 38/79 (48%), Positives = 45/79 (56%), Gaps = 6/79 (7%) Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGP--PGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559 + + GP+G +G G+P +PG GPPG EG G GPPG QG G VG+PG Sbjct: 287 EAAHGPRGLKGEKGEPAVL----EPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGER 342 Query: 560 GPRGLPGLPGVPGMPGPKG 578 GP G GLPG G PGP G Sbjct: 343 GPPGRAGLPGSDGAPGPPG 361 Score = 49.7 bits (117), Expect = 1e-05 Identities = 40/124 (32%), Positives = 49/124 (39%), Gaps = 37/124 (29%) Query: 495 ERGGKGSKGSQGPKGSRGSPG-------KPGPQGPSGDPGPPG-----------PPGKEG 536 E G + +Q P ++ SP +P Q P PG PP +E Sbjct: 229 EGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEA 288 Query: 537 LPGPQGPPGFQGLQGTVGE-------------PGVPGPRGLPGLPGVPGMPGPKGPPGPP 583 GP+G L+G GE PG GP GL G PG+ G PGP G PG Sbjct: 289 AHGPRG------LKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGER 342 Query: 584 GPSG 587 GP G Sbjct: 343 GPPG 346 Score = 46.6 bits (109), Expect = 8e-05 Identities = 25/60 (41%), Positives = 31/60 (51%), Gaps = 6/60 (10%) Query: 555 EPGVPGPRGLPGLPGVPGMPGP----KGPPGPPGPSGAVVPLALQNEPTPA--PEDNGCP 608 E GPRGL G G P + P +GPPGP GP+G + P +Q P P P + G P Sbjct: 286 EEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPP 345 >gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo sapiens] Length = 1629 Score = 162 bits (409), Expect = 1e-39 Identities = 89/188 (47%), Positives = 99/188 (52%), Gaps = 30/188 (15%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPG---PAGERGPIGPAGPPGERG 497 L G PG +GP+G G G PG +G KG +G G+ GP G P G RG GP G G+ G Sbjct: 693 LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG 752 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGP---PGPPGKEGLP---------------G 539 KG+ G GP G G G PGPQGP+G PGP PGPPGK+GLP G Sbjct: 753 AKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTG 812 Query: 540 PQGPPGFQGLQGTVGE---------PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVV 590 P GPPG G QG GE PG PGP G GLPG G G KG PGPPG G Sbjct: 813 PPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDG 872 Query: 591 PLALQNEP 598 P L+ P Sbjct: 873 PAGLRGFP 880 Score = 160 bits (404), Expect = 5e-39 Identities = 83/158 (52%), Positives = 97/158 (61%), Gaps = 9/158 (5%) Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGP 492 + F L G PG +G RGD G+QG PGP G G++G+ GE GP PG +G RG +GP GP Sbjct: 451 RGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGP 510 Query: 493 PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQ---GPPGFQGL 549 PG G G +G GP+G +GS G PQG G PG G PG +GLPGPQ GP G +G Sbjct: 511 PGIPGPPGVRGMDGPQGPKGSLG---PQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 567 Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 QG G PG+PG G PG PG G PG KG GP GP G Sbjct: 568 QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQG 605 Score = 159 bits (403), Expect = 7e-39 Identities = 82/164 (50%), Positives = 96/164 (58%), Gaps = 18/164 (10%) Query: 442 QGPPGPRGPRGDRGSQGPPGP------TGNKGQKGE---KGEPGPPGPAGERGPIGPAGP 492 +G PGP+GP G G +GPPGP G+ GQ+GE +G+ GPPGP G GP G AG Sbjct: 769 RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGE 828 Query: 493 PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552 G G +G G GP G +G PG G +G GDPGPPG PGK+G G +G PG +GL GT Sbjct: 829 TGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGT 888 Query: 553 VGEPGV---------PGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G PG+ PGP G PG G G GP GPPG PGP G Sbjct: 889 AGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQG 932 Score = 159 bits (402), Expect = 9e-39 Identities = 84/182 (46%), Positives = 96/182 (52%), Gaps = 36/182 (19%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP---------- 492 GP G RGP G RG +GP G TG G KG G GP GP GERG GP GP Sbjct: 728 GPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPP 787 Query: 493 -----------PGERGGKGSKGSQGPKGS------RGSPGKPGPQGPSGDPGPPGPPGKE 535 PG+RG G +G GP G +G+ G+ GP G G PGPPGPPG++ Sbjct: 788 GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ 847 Query: 536 GLP---------GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPS 586 GLP G GPPG G G G G PG RGLPG G PG+ G +GP GPPGP+ Sbjct: 848 GLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPA 907 Query: 587 GA 588 G+ Sbjct: 908 GS 909 Score = 159 bits (402), Expect = 9e-39 Identities = 84/182 (46%), Positives = 99/182 (54%), Gaps = 30/182 (16%) Query: 443 GPPGPRGPRGDRGSQGPPGPTG---------------------NKGQKGEKGEPGPPGPA 481 GPPGP+GP GD G +G PGP G ++G+ GE G+PG PGP Sbjct: 1142 GPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPT 1201 Query: 482 GERGPIGP------AGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKE 535 GE GP GP AG PG G +G KG++G G+ G+PGK GP GP+G G PGP G Sbjct: 1202 GENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLR 1261 Query: 536 GLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQ 595 GLPG G QG G G+ G PGP G PGLPG+ G G KG G PG G + P Q Sbjct: 1262 GLPGSVGQ---QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQ 1318 Query: 596 NE 597 E Sbjct: 1319 GE 1320 Score = 158 bits (399), Expect = 2e-38 Identities = 82/148 (55%), Positives = 88/148 (59%), Gaps = 12/148 (8%) Query: 443 GPPGPRGPRGDRGS---QGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499 GPPGPRGP G G+ QGPPG GN G GEKGEPG G G +G G GP GERG K Sbjct: 1073 GPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEK 1132 Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559 G G G PG PGP+GP+GD GP G PG G PG GPPG +G G G+ G Sbjct: 1133 GESGQP------GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG-EG--GPRGQDGAK 1183 Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G RG G PG PG PGP G GPPGP G Sbjct: 1184 GDRGEDGEPGQPGSPGPTGENGPPGPLG 1211 Score = 157 bits (397), Expect = 3e-38 Identities = 86/167 (51%), Positives = 93/167 (55%), Gaps = 18/167 (10%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---PAGPPG----- 494 G GP GP G G QGPPG G KG GEKG GP G G +GP+G PAGPPG Sbjct: 917 GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGED 976 Query: 495 ----ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQ 550 E G G KG++G KG G PG PGP GP G PG G G+ G GPQG G +G + Sbjct: 977 GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1036 Query: 551 GTVGEPGVPGPRGLPGLPGVPGMP------GPKGPPGPPGPSGAVVP 591 GT G G PGP GL GLPG G GP GPPGPPGP G P Sbjct: 1037 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGP 1083 Score = 157 bits (396), Expect = 4e-38 Identities = 81/161 (50%), Positives = 94/161 (58%), Gaps = 3/161 (1%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GPPG G +G G G PG G +G KG G PG PG +GE+G G +G G RG +G Sbjct: 677 GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 736 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G +G +G RG+ GK G +G SG GP GPPG+ GLPGPQGP GF G + G PG PG Sbjct: 737 GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK---GPPGPPGKD 793 Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPE 603 GLPG PG G G +G GPPGP G V P E P E Sbjct: 794 GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 834 Score = 157 bits (396), Expect = 4e-38 Identities = 88/206 (42%), Positives = 94/206 (45%), Gaps = 45/206 (21%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GPPG G GD+G G PG G KG KGE G PGPPGP G G G AG GE G +G + Sbjct: 968 GPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQ 1027 Query: 503 GS------------------------QGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLP 538 G GP G +G G GP GP G PGP GP G G Sbjct: 1028 GHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGAD 1087 Query: 539 GPQGP---------------PGFQGLQGTVGEPGVPGPR------GLPGLPGVPGMPGPK 577 GPQGP PG G G GEPGV GPR G G PG PG PGPK Sbjct: 1088 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK 1147 Query: 578 GPPGPPGPSGAVVPLALQNEPTPAPE 603 GP G GP G P+ +P P E Sbjct: 1148 GPTGDDGPKGNPGPVGFPGDPGPPGE 1173 Score = 154 bits (390), Expect = 2e-37 Identities = 82/158 (51%), Positives = 92/158 (58%), Gaps = 15/158 (9%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE---PGPPGPAGERGPIGPAGPPGERGG 498 +G PG G +GDRG G PG G KG +G+ G PGPPG GERG G GP G G Sbjct: 439 RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 498 Query: 499 KGSKGSQGPKGSRGSPGKPG------PQGPSGDPGP---PGPPGKEGLPGPQGPPGFQGL 549 G +G GPKG G PG PG PQGP G GP PGPPG++G PG QG PG Sbjct: 499 SGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG---P 555 Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 QG +G G GP+G PGLPG+PG GP G PG GP G Sbjct: 556 QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPG 593 Score = 153 bits (386), Expect = 6e-37 Identities = 84/190 (44%), Positives = 98/190 (51%), Gaps = 45/190 (23%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKG------QKGEKGEPGPPGPAGERGPIGPAGPPGE 495 QG G GP G+RG GPPGP G +G ++G KG+PGPPG G+ GP G G PGE Sbjct: 823 QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE 882 Query: 496 RG------GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGL 549 RG G G KG++GP G G G PG +G +G GP GPPG+ PGPQGPPG G Sbjct: 883 RGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGR---PGPQGPPGAAGE 939 Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPP----------------------------- 580 +G GE G GP G G+ G G+PGP GPP Sbjct: 940 KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 999 Query: 581 -GPPGPSGAV 589 GPPGP G V Sbjct: 1000 PGPPGPIGPV 1009 Score = 152 bits (383), Expect = 1e-36 Identities = 78/172 (45%), Positives = 95/172 (55%), Gaps = 8/172 (4%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI---GPAGPPGERG 497 +QG PG +GPRG+RG +G G G G G KG G GP G GP+ G GPPGE G Sbjct: 1116 IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGG 1175 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557 +G G++G +G G PG+PG GP+G+ GPPGP GK GP G PG +G QG G G Sbjct: 1176 PRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR---GPAGSPGSEGRQGGKGAKG 1232 Query: 558 VPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609 PG G PG G G GP G PGP G G +P ++ + P PP Sbjct: 1233 DPGAIGAPGKTGPVGPAGPAGKPGPDGLRG--LPGSVGQQGRPGATGQAGPP 1282 Score = 151 bits (382), Expect = 2e-36 Identities = 77/159 (48%), Positives = 88/159 (55%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G GP GP G RG G PG G +G KG KG+PG G G+ GP+GPAGP G+ G G + Sbjct: 1202 GENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLR 1261 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G G G +G PG G GP G GPPG PG G G +G G GL G +G PG G + Sbjct: 1262 GLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEK 1321 Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601 G GLPG G PG KG G PG SG + P P PA Sbjct: 1322 GDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPA 1360 Score = 149 bits (376), Expect = 9e-36 Identities = 82/171 (47%), Positives = 91/171 (53%), Gaps = 24/171 (14%) Query: 441 LQGPPGPRGPRGDRGSQGP---PGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERG 497 L GPPG G RG G+ G PG G KG +G G PG PG G RG G G PG G Sbjct: 420 LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 479 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQ---GPSGDPGPPGPPGKEGLPGPQGP---------PG 545 G +G G G RG PG+ GP+ GP G PG PGPPG G+ GPQGP PG Sbjct: 480 EDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG 539 Query: 546 FQGLQGTVGEPGVPGPRGL---------PGLPGVPGMPGPKGPPGPPGPSG 587 G QGT G G+PGP+G G PG+PGMPG GPPG PG G Sbjct: 540 PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEG 590 Score = 147 bits (372), Expect = 3e-35 Identities = 81/189 (42%), Positives = 97/189 (51%), Gaps = 22/189 (11%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG------PIGPAGPPGER 496 G PG RGP+G G++G G G G G G G PGP+GE+G P+GP GPPG R Sbjct: 1019 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1078 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G G G+ GP+G G G GP G G+PG G PG +G PG +GP G +G +G G+P Sbjct: 1079 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP 1138 Query: 557 GVP------------GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP----TP 600 G P GP+G PG G PG PGP G GP G GA EP +P Sbjct: 1139 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSP 1198 Query: 601 APEDNGCPP 609 P PP Sbjct: 1199 GPTGENGPP 1207 Score = 145 bits (367), Expect = 1e-34 Identities = 78/160 (48%), Positives = 86/160 (53%), Gaps = 7/160 (4%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G GP GP G G GP G G G G++G PG G AG GP+GP G PG RG G+K Sbjct: 1241 GKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAK 1300 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G +G G G G PG QG GD G PGP G G G G PG G G G PG+PGP Sbjct: 1301 GEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPA 1360 Query: 563 GLPGLPGVPGMPGPK------GPPGPPGPSGAVV-PLALQ 595 G G G G GPK GPPG PGP G V+ PL +Q Sbjct: 1361 GPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQ 1400 Score = 144 bits (363), Expect = 3e-34 Identities = 81/170 (47%), Positives = 88/170 (51%), Gaps = 10/170 (5%) Query: 448 RGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGP 507 RGP G G G PGP G G G KGE G GP G RGP G GPPG+ G +G G+ G Sbjct: 379 RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 438 Query: 508 KGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGL 567 +G G PG G +G G PG PG G G G QG PG G G G+ G GPRGLPG Sbjct: 439 RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 498 Query: 568 PGVPGMPGPKGPPGPP---------GPSGAVVPLALQNEPTPAPEDNGCP 608 G G+ GPKGPPG P GP G L Q EP P P G P Sbjct: 499 SGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP-PGQQGTP 547 Score = 142 bits (357), Expect = 1e-33 Identities = 77/160 (48%), Positives = 89/160 (55%), Gaps = 3/160 (1%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 QG PGP G +G G+QG PGP G G GEKG G PG G G GP G PG+ G G+ Sbjct: 535 QGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGT 594 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG---LQGTVGEPGV 558 KG+QGP G +G G PGP+G G G G G +G G G PGF+G ++G GE GV Sbjct: 595 KGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV 654 Query: 559 PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598 PG RG G G G GP G PGPPG G L + P Sbjct: 655 PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLP 694 Score = 140 bits (354), Expect = 3e-33 Identities = 75/166 (45%), Positives = 87/166 (52%), Gaps = 9/166 (5%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 ++G GP+GP+G G QG PGP G +G G +G PGP G G G GP G PG G G Sbjct: 519 VRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 578 Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP- 559 S G G G G PG G QGPSG GP G PG G+ G G G +G +G GE G P Sbjct: 579 SDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPG 638 Query: 560 --------GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNE 597 G RG G+PG G GP+GP G GP+G P L E Sbjct: 639 FKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGE 684 Score = 140 bits (353), Expect = 4e-33 Identities = 78/179 (43%), Positives = 97/179 (54%), Gaps = 11/179 (6%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGE---KGEPGPPGPAGERGPIGPAGPPGERGGK 499 G GP+GPRG +G GPPG G +G+ G +G PG PG G+RG G G PGE+G + Sbjct: 407 GDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHR 466 Query: 500 GSKGSQG------PKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553 G G+QG G RG G+ GP+G G+ GP G G +G PG GPPG +G+ G Sbjct: 467 GDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQ 526 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP--TPAPEDNGCPPH 610 G G GP+G PG PG G PG +G PGP G G Q +P P +G P H Sbjct: 527 GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 585 Score = 139 bits (350), Expect = 9e-33 Identities = 85/197 (43%), Positives = 90/197 (45%), Gaps = 51/197 (25%) Query: 442 QGPPGPRGPRG---DRGSQGPPGPTGNKGQKGEK-------------------------- 472 QGP GP+GP G RG +G G G KG KGEK Sbjct: 598 QGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGS 657 Query: 473 -GEPGPPGPAGERGPIGPAGPPGERGGKGS---------KGSQGPKGSRGSPGKP----- 517 GE GP GP G GP G GPPG G KG G QGPKGS G PG P Sbjct: 658 RGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGE 717 Query: 518 -------GPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGV 570 G GP G+ GP GP G+ G G G G +G G G G PG RGLPG G Sbjct: 718 KGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGP 777 Query: 571 PGMPGPKGPPGPPGPSG 587 G PGPKGPPGPPG G Sbjct: 778 NGFPGPKGPPGPPGKDG 794 Score = 139 bits (349), Expect = 1e-32 Identities = 81/181 (44%), Positives = 92/181 (50%), Gaps = 18/181 (9%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG---PPGPAGERGPIGPAGP---PG 494 L GP G GP G++G QG PG G G G G PG PPG G +GP GP GP PG Sbjct: 552 LPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPG 611 Query: 495 ERGGKGS------KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG 548 RG KG KG +G KG G PG G G GD G G PG G GP+GP G G Sbjct: 612 PRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTG 671 Query: 549 LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGP------PGPPGPSGAVVPLALQNEPTPAP 602 G G PG+ G +G G+PG+PG PG +GP PG PG SG L + P Sbjct: 672 PTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG 731 Query: 603 E 603 E Sbjct: 732 E 732 Score = 137 bits (346), Expect = 3e-32 Identities = 76/152 (50%), Positives = 81/152 (53%), Gaps = 12/152 (7%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG---ERGPIG---PAGPPGER 496 G GP G RG G +G PG G G KG +G GPPGPAG ERG G P GPPG Sbjct: 869 GKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGR- 927 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G QGP G+ G G PG +GP G G G G GLPGP GPPG G G GE Sbjct: 928 -----PGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 982 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588 G PG +G G G G PGP GP GP G GA Sbjct: 983 GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1014 Score = 136 bits (342), Expect = 8e-32 Identities = 76/170 (44%), Positives = 91/170 (53%), Gaps = 12/170 (7%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGE---------KGEPGPPGPAGERGPIGPAG 491 L+GPPGP G G G G PG G KG+ G+ +G GPPG AG RG G G Sbjct: 378 LRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADG 437 Query: 492 PPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQG 551 G G G KG +G G G PG+ G +G +G G PGPPG++G G G G +GL G Sbjct: 438 ARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPG 497 Query: 552 TVGEPGVPGPRGLPGLPGVP---GMPGPKGPPGPPGPSGAVVPLALQNEP 598 G G+ GP+G PG+PG P GM GP+GP G GP G P Q P Sbjct: 498 ESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTP 547 Score = 136 bits (342), Expect = 8e-32 Identities = 81/191 (42%), Positives = 94/191 (49%), Gaps = 21/191 (10%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 L G PG GP G G +GPPG GN+G G +G G PGP G +G G G G +G KG Sbjct: 573 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 632 Query: 501 S------KGSQGPKGSRGSPGKPG------PQGPS------GDPGPP---GPPGKEGLPG 539 KG G KG RG G PG P+GP GDPGPP G GK G+PG Sbjct: 633 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 692 Query: 540 PQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPT 599 G PG QG +G++G PG PG G G G+ G GP+G GP GP G P + Sbjct: 693 LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG 752 Query: 600 PAPEDNGCPPH 610 G PH Sbjct: 753 AKGTSGGDGPH 763 Score = 131 bits (330), Expect = 2e-30 Identities = 82/216 (37%), Positives = 94/216 (43%), Gaps = 58/216 (26%) Query: 440 ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGE---- 495 +++GPPGP GP G GPPG GN G G+ GE GPPG AG G G GPPG Sbjct: 289 LVEGPPGPEGPAG---LIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLML 345 Query: 496 ---------------------------------RGGKGSKGSQGPKGSRGSPGKPGPQGP 522 RG G G G G G PG PG +G Sbjct: 346 PFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGE 405 Query: 523 SGDPGPPGPPGKEGLPGP------QGPPGFQGLQGTVGEPGVPGPRGLPGLPGVP----- 571 SGD GP GP G +GL GP +G G G +G G+PGV G RG GLPG+P Sbjct: 406 SGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGH 465 Query: 572 -------GMPGPKGPPGPPGPSGAVVPLALQNEPTP 600 G+PGP G G G G + P L E P Sbjct: 466 RGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGP 501 Score = 125 bits (314), Expect = 1e-28 Identities = 70/145 (48%), Positives = 80/145 (55%), Gaps = 9/145 (6%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 L G G +G G G GPPGP G G G +G+ G G G G IG GPPGE+G KG Sbjct: 1263 LPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKG 1322 Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPG 560 +G GP+GS G G+ G G SG GP GPP GLPGP GP G +G G PG G Sbjct: 1323 DRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP---GLPGPAGPKGAKGATG----PG--G 1373 Query: 561 PRGLPGLPGVPGMPGPKGPPGPPGP 585 P+G G+ G PG PGP G P P Sbjct: 1374 PKGEKGVQGPPGHPGPPGEVIQPLP 1398 Score = 92.4 bits (228), Expect = 1e-18 Identities = 65/178 (36%), Positives = 71/178 (39%), Gaps = 61/178 (34%) Query: 456 SQGPPGPTGNKGQKGEKGEPG--PPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGS 513 SQ GP +G KGEKGEP PG E GPPG +GP G G Sbjct: 265 SQAAHGP---RGLKGEKGEPAVLEPGMLVE-------GPPGP---------EGPAGLIGP 305 Query: 514 PGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPG---------------------------- 545 PG G GP GDPG GPPG+ GLPG G PG Sbjct: 306 PGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEA 365 Query: 546 ------------FQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 +G G +G G PGP G PG PG+ G G GP GP GP G P Sbjct: 366 QAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGP 423 Score = 47.8 bits (112), Expect = 4e-05 Identities = 27/63 (42%), Positives = 30/63 (47%), Gaps = 13/63 (20%) Query: 538 PGPQGPPGFQGLQGTVGE-------------PGVPGPRGLPGLPGVPGMPGPKGPPGPPG 584 P Q G +GL+G GE PG GP GL G PG+ G PGP G PG G Sbjct: 263 PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 322 Query: 585 PSG 587 P G Sbjct: 323 PPG 325 >gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo sapiens] Length = 1736 Score = 162 bits (409), Expect = 1e-39 Identities = 89/188 (47%), Positives = 99/188 (52%), Gaps = 30/188 (15%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPG---PAGERGPIGPAGPPGERG 497 L G PG +GP+G G G PG +G KG +G G+ GP G P G RG GP G G+ G Sbjct: 800 LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG 859 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGP---PGPPGKEGLP---------------G 539 KG+ G GP G G G PGPQGP+G PGP PGPPGK+GLP G Sbjct: 860 AKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTG 919 Query: 540 PQGPPGFQGLQGTVGE---------PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVV 590 P GPPG G QG GE PG PGP G GLPG G G KG PGPPG G Sbjct: 920 PPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDG 979 Query: 591 PLALQNEP 598 P L+ P Sbjct: 980 PAGLRGFP 987 Score = 160 bits (404), Expect = 5e-39 Identities = 83/158 (52%), Positives = 97/158 (61%), Gaps = 9/158 (5%) Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGP 492 + F L G PG +G RGD G+QG PGP G G++G+ GE GP PG +G RG +GP GP Sbjct: 558 RGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGP 617 Query: 493 PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQ---GPPGFQGL 549 PG G G +G GP+G +GS G PQG G PG G PG +GLPGPQ GP G +G Sbjct: 618 PGIPGPPGVRGMDGPQGPKGSLG---PQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 674 Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 QG G PG+PG G PG PG G PG KG GP GP G Sbjct: 675 QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQG 712 Score = 159 bits (403), Expect = 7e-39 Identities = 80/158 (50%), Positives = 92/158 (58%), Gaps = 12/158 (7%) Query: 442 QGP---PGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGG 498 QGP PGP+GP G G G PG G +G+ G +G+ GPPGP G GP G AG G G Sbjct: 882 QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 941 Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV 558 +G G GP G +G PG G +G GDPGPPG PGK+G G +G PG +GL GT G PG+ Sbjct: 942 RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGL 1001 Query: 559 ---------PGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 PGP G PG G G GP GPPG PGP G Sbjct: 1002 KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQG 1039 Score = 159 bits (402), Expect = 9e-39 Identities = 84/182 (46%), Positives = 96/182 (52%), Gaps = 36/182 (19%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP---------- 492 GP G RGP G RG +GP G TG G KG G GP GP GERG GP GP Sbjct: 835 GPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPP 894 Query: 493 -----------PGERGGKGSKGSQGPKGS------RGSPGKPGPQGPSGDPGPPGPPGKE 535 PG+RG G +G GP G +G+ G+ GP G G PGPPGPPG++ Sbjct: 895 GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ 954 Query: 536 GLP---------GPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPS 586 GLP G GPPG G G G G PG RGLPG G PG+ G +GP GPPGP+ Sbjct: 955 GLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPA 1014 Query: 587 GA 588 G+ Sbjct: 1015 GS 1016 Score = 159 bits (402), Expect = 9e-39 Identities = 84/182 (46%), Positives = 99/182 (54%), Gaps = 30/182 (16%) Query: 443 GPPGPRGPRGDRGSQGPPGPTG---------------------NKGQKGEKGEPGPPGPA 481 GPPGP+GP GD G +G PGP G ++G+ GE G+PG PGP Sbjct: 1249 GPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPT 1308 Query: 482 GERGPIGP------AGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKE 535 GE GP GP AG PG G +G KG++G G+ G+PGK GP GP+G G PGP G Sbjct: 1309 GENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLR 1368 Query: 536 GLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQ 595 GLPG G QG G G+ G PGP G PGLPG+ G G KG G PG G + P Q Sbjct: 1369 GLPGSVGQ---QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQ 1425 Query: 596 NE 597 E Sbjct: 1426 GE 1427 Score = 158 bits (399), Expect = 2e-38 Identities = 82/148 (55%), Positives = 88/148 (59%), Gaps = 12/148 (8%) Query: 443 GPPGPRGPRGDRGS---QGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499 GPPGPRGP G G+ QGPPG GN G GEKGEPG G G +G G GP GERG K Sbjct: 1180 GPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEK 1239 Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP 559 G G G PG PGP+GP+GD GP G PG G PG GPPG +G G G+ G Sbjct: 1240 GESGQP------GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG-EG--GPRGQDGAK 1290 Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G RG G PG PG PGP G GPPGP G Sbjct: 1291 GDRGEDGEPGQPGSPGPTGENGPPGPLG 1318 Score = 157 bits (397), Expect = 3e-38 Identities = 86/167 (51%), Positives = 93/167 (55%), Gaps = 18/167 (10%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---PAGPPG----- 494 G GP GP G G QGPPG G KG GEKG GP G G +GP+G PAGPPG Sbjct: 1024 GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGED 1083 Query: 495 ----ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQ 550 E G G KG++G KG G PG PGP GP G PG G G+ G GPQG G +G + Sbjct: 1084 GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1143 Query: 551 GTVGEPGVPGPRGLPGLPGVPGMP------GPKGPPGPPGPSGAVVP 591 GT G G PGP GL GLPG G GP GPPGPPGP G P Sbjct: 1144 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGP 1190 Score = 157 bits (396), Expect = 4e-38 Identities = 81/161 (50%), Positives = 94/161 (58%), Gaps = 3/161 (1%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GPPG G +G G G PG G +G KG G PG PG +GE+G G +G G RG +G Sbjct: 784 GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 843 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G +G +G RG+ GK G +G SG GP GPPG+ GLPGPQGP GF G + G PG PG Sbjct: 844 GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK---GPPGPPGKD 900 Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPE 603 GLPG PG G G +G GPPGP G V P E P E Sbjct: 901 GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 941 Score = 157 bits (396), Expect = 4e-38 Identities = 88/206 (42%), Positives = 94/206 (45%), Gaps = 45/206 (21%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GPPG G GD+G G PG G KG KGE G PGPPGP G G G AG GE G +G + Sbjct: 1075 GPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQ 1134 Query: 503 GS------------------------QGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLP 538 G GP G +G G GP GP G PGP GP G G Sbjct: 1135 GHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGAD 1194 Query: 539 GPQGP---------------PGFQGLQGTVGEPGVPGPR------GLPGLPGVPGMPGPK 577 GPQGP PG G G GEPGV GPR G G PG PG PGPK Sbjct: 1195 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK 1254 Query: 578 GPPGPPGPSGAVVPLALQNEPTPAPE 603 GP G GP G P+ +P P E Sbjct: 1255 GPTGDDGPKGNPGPVGFPGDPGPPGE 1280 Score = 154 bits (390), Expect = 2e-37 Identities = 82/158 (51%), Positives = 92/158 (58%), Gaps = 15/158 (9%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE---PGPPGPAGERGPIGPAGPPGERGG 498 +G PG G +GDRG G PG G KG +G+ G PGPPG GERG G GP G G Sbjct: 546 RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 605 Query: 499 KGSKGSQGPKGSRGSPGKP------GPQGPSGDPGP---PGPPGKEGLPGPQGPPGFQGL 549 G +G GPKG G PG P GPQGP G GP PGPPG++G PG QG P G Sbjct: 606 SGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP---GP 662 Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 QG +G G GP+G PGLPG+PG GP G PG GP G Sbjct: 663 QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPG 700 Score = 153 bits (386), Expect = 6e-37 Identities = 84/190 (44%), Positives = 98/190 (51%), Gaps = 45/190 (23%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKG------QKGEKGEPGPPGPAGERGPIGPAGPPGE 495 QG G GP G+RG GPPGP G +G ++G KG+PGPPG G+ GP G G PGE Sbjct: 930 QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE 989 Query: 496 RG------GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGL 549 RG G G KG++GP G G G PG +G +G GP GPPG+ PGPQGPPG G Sbjct: 990 RGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGR---PGPQGPPGAAGE 1046 Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPP----------------------------- 580 +G GE G GP G G+ G G+PGP GPP Sbjct: 1047 KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 1106 Query: 581 -GPPGPSGAV 589 GPPGP G V Sbjct: 1107 PGPPGPIGPV 1116 Score = 152 bits (383), Expect = 1e-36 Identities = 78/172 (45%), Positives = 95/172 (55%), Gaps = 8/172 (4%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI---GPAGPPGERG 497 +QG PG +GPRG+RG +G G G G G KG G GP G GP+ G GPPGE G Sbjct: 1223 IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGG 1282 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557 +G G++G +G G PG+PG GP+G+ GPPGP GK GP G PG +G QG G G Sbjct: 1283 PRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR---GPAGSPGSEGRQGGKGAKG 1339 Query: 558 VPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609 PG G PG G G GP G PGP G G +P ++ + P PP Sbjct: 1340 DPGAIGAPGKTGPVGPAGPAGKPGPDGLRG--LPGSVGQQGRPGATGQAGPP 1389 Score = 151 bits (382), Expect = 2e-36 Identities = 77/159 (48%), Positives = 88/159 (55%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G GP GP G RG G PG G +G KG KG+PG G G+ GP+GPAGP G+ G G + Sbjct: 1309 GENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLR 1368 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G G G +G PG G GP G GPPG PG G G +G G GL G +G PG G + Sbjct: 1369 GLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEK 1428 Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601 G GLPG G PG KG G PG SG + P P PA Sbjct: 1429 GDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPA 1467 Score = 149 bits (376), Expect = 9e-36 Identities = 82/171 (47%), Positives = 91/171 (53%), Gaps = 24/171 (14%) Query: 441 LQGPPGPRGPRGDRGSQGP---PGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERG 497 L GPPG G RG G+ G PG G KG +G G PG PG G RG G G PG G Sbjct: 527 LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 586 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQ---GPSGDPGPPGPPGKEGLPGPQGP---------PG 545 G +G G G RG PG+ GP+ GP G PG PGPPG G+ GPQGP PG Sbjct: 587 EDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG 646 Query: 546 FQGLQGTVGEPGVPGPRGL---------PGLPGVPGMPGPKGPPGPPGPSG 587 G QGT G G+PGP+G G PG+PGMPG GPPG PG G Sbjct: 647 PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEG 697 Score = 147 bits (372), Expect = 3e-35 Identities = 81/189 (42%), Positives = 97/189 (51%), Gaps = 22/189 (11%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG------PIGPAGPPGER 496 G PG RGP+G G++G G G G G G G PGP+GE+G P+GP GPPG R Sbjct: 1126 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1185 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G G G+ GP+G G G GP G G+PG G PG +G PG +GP G +G +G G+P Sbjct: 1186 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP 1245 Query: 557 GVP------------GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP----TP 600 G P GP+G PG G PG PGP G GP G GA EP +P Sbjct: 1246 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSP 1305 Query: 601 APEDNGCPP 609 P PP Sbjct: 1306 GPTGENGPP 1314 Score = 145 bits (367), Expect = 1e-34 Identities = 78/160 (48%), Positives = 86/160 (53%), Gaps = 7/160 (4%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G GP GP G G GP G G G G++G PG G AG GP+GP G PG RG G+K Sbjct: 1348 GKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAK 1407 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G +G G G G PG QG GD G PGP G G G G PG G G G PG+PGP Sbjct: 1408 GEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPA 1467 Query: 563 GLPGLPGVPGMPGPK------GPPGPPGPSGAVV-PLALQ 595 G G G G GPK GPPG PGP G V+ PL +Q Sbjct: 1468 GPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQ 1507 Score = 144 bits (363), Expect = 3e-34 Identities = 81/170 (47%), Positives = 88/170 (51%), Gaps = 10/170 (5%) Query: 448 RGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGP 507 RGP G G G PGP G G G KGE G GP G RGP G GPPG+ G +G G+ G Sbjct: 486 RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 545 Query: 508 KGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGL 567 +G G PG G +G G PG PG G G G QG PG G G G+ G GPRGLPG Sbjct: 546 RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 605 Query: 568 PGVPGMPGPKGPPGPP---------GPSGAVVPLALQNEPTPAPEDNGCP 608 G G+ GPKGPPG P GP G L Q EP P P G P Sbjct: 606 SGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP-PGQQGTP 654 Score = 142 bits (357), Expect = 1e-33 Identities = 77/160 (48%), Positives = 89/160 (55%), Gaps = 3/160 (1%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 QG PGP G +G G+QG PGP G G GEKG G PG G G GP G PG+ G G+ Sbjct: 642 QGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGT 701 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG---LQGTVGEPGV 558 KG+QGP G +G G PGP+G G G G G +G G G PGF+G ++G GE GV Sbjct: 702 KGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV 761 Query: 559 PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598 PG RG G G G GP G PGPPG G L + P Sbjct: 762 PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLP 801 Score = 140 bits (354), Expect = 3e-33 Identities = 75/166 (45%), Positives = 87/166 (52%), Gaps = 9/166 (5%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 ++G GP+GP+G G QG PGP G +G G +G PGP G G G GP G PG G G Sbjct: 626 VRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 685 Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVP- 559 S G G G G PG G QGPSG GP G PG G+ G G G +G +G GE G P Sbjct: 686 SDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPG 745 Query: 560 --------GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNE 597 G RG G+PG G GP+GP G GP+G P L E Sbjct: 746 FKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGE 791 Score = 140 bits (353), Expect = 4e-33 Identities = 78/179 (43%), Positives = 97/179 (54%), Gaps = 11/179 (6%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGE---KGEPGPPGPAGERGPIGPAGPPGERGGK 499 G GP+GPRG +G GPPG G +G+ G +G PG PG G+RG G G PGE+G + Sbjct: 514 GDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHR 573 Query: 500 GSKGSQG------PKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553 G G+QG G RG G+ GP+G G+ GP G G +G PG GPPG +G+ G Sbjct: 574 GDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQ 633 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP--TPAPEDNGCPPH 610 G G GP+G PG PG G PG +G PGP G G Q +P P +G P H Sbjct: 634 GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 692 Score = 139 bits (350), Expect = 9e-33 Identities = 85/197 (43%), Positives = 90/197 (45%), Gaps = 51/197 (25%) Query: 442 QGPPGPRGPRG---DRGSQGPPGPTGNKGQKGEK-------------------------- 472 QGP GP+GP G RG +G G G KG KGEK Sbjct: 705 QGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGS 764 Query: 473 -GEPGPPGPAGERGPIGPAGPPGERGGKGS---------KGSQGPKGSRGSPGKP----- 517 GE GP GP G GP G GPPG G KG G QGPKGS G PG P Sbjct: 765 RGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGE 824 Query: 518 -------GPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGV 570 G GP G+ GP GP G+ G G G G +G G G G PG RGLPG G Sbjct: 825 KGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGP 884 Query: 571 PGMPGPKGPPGPPGPSG 587 G PGPKGPPGPPG G Sbjct: 885 NGFPGPKGPPGPPGKDG 901 Score = 139 bits (349), Expect = 1e-32 Identities = 81/181 (44%), Positives = 92/181 (50%), Gaps = 18/181 (9%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG---PPGPAGERGPIGPAGP---PG 494 L GP G GP G++G QG PG G G G G PG PPG G +GP GP GP PG Sbjct: 659 LPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPG 718 Query: 495 ERGGKGS------KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG 548 RG KG KG +G KG G PG G G GD G G PG G GP+GP G G Sbjct: 719 PRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTG 778 Query: 549 LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGP------PGPPGPSGAVVPLALQNEPTPAP 602 G G PG+ G +G G+PG+PG PG +GP PG PG SG L + P Sbjct: 779 PTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG 838 Query: 603 E 603 E Sbjct: 839 E 839 Score = 137 bits (346), Expect = 3e-32 Identities = 76/152 (50%), Positives = 81/152 (53%), Gaps = 12/152 (7%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG---ERGPIG---PAGPPGER 496 G GP G RG G +G PG G G KG +G GPPGPAG ERG G P GPPG Sbjct: 976 GKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGR- 1034 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G QGP G+ G G PG +GP G G G G GLPGP GPPG G G GE Sbjct: 1035 -----PGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 1089 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588 G PG +G G G G PGP GP GP G GA Sbjct: 1090 GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1121 Score = 136 bits (342), Expect = 8e-32 Identities = 76/170 (44%), Positives = 91/170 (53%), Gaps = 12/170 (7%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGE---------KGEPGPPGPAGERGPIGPAG 491 L+GPPGP G G G G PG G KG+ G+ +G GPPG AG RG G G Sbjct: 485 LRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADG 544 Query: 492 PPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQG 551 G G G KG +G G G PG+ G +G +G G PGPPG++G G G G +GL G Sbjct: 545 ARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPG 604 Query: 552 TVGEPGVPGPRGLPGLPGVP---GMPGPKGPPGPPGPSGAVVPLALQNEP 598 G G+ GP+G PG+PG P GM GP+GP G GP G P Q P Sbjct: 605 ESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTP 654 Score = 136 bits (342), Expect = 8e-32 Identities = 81/191 (42%), Positives = 94/191 (49%), Gaps = 21/191 (10%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 L G PG GP G G +GPPG GN+G G +G G PGP G +G G G G +G KG Sbjct: 680 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 739 Query: 501 S------KGSQGPKGSRGSPGKPG------PQGPS------GDPGPP---GPPGKEGLPG 539 KG G KG RG G PG P+GP GDPGPP G GK G+PG Sbjct: 740 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 799 Query: 540 PQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPT 599 G PG QG +G++G PG PG G G G+ G GP+G GP GP G P + Sbjct: 800 LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG 859 Query: 600 PAPEDNGCPPH 610 G PH Sbjct: 860 AKGTSGGDGPH 870 Score = 131 bits (330), Expect = 2e-30 Identities = 82/216 (37%), Positives = 94/216 (43%), Gaps = 58/216 (26%) Query: 440 ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGE---- 495 +++GPPGP GP G GPPG GN G G+ GE GPPG AG G G GPPG Sbjct: 396 LVEGPPGPEGPAG---LIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLML 452 Query: 496 ---------------------------------RGGKGSKGSQGPKGSRGSPGKPGPQGP 522 RG G G G G G PG PG +G Sbjct: 453 PFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGE 512 Query: 523 SGDPGPPGPPGKEGLPGP------QGPPGFQGLQGTVGEPGVPGPRGLPGLPGVP----- 571 SGD GP GP G +GL GP +G G G +G G+PGV G RG GLPG+P Sbjct: 513 SGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGH 572 Query: 572 -------GMPGPKGPPGPPGPSGAVVPLALQNEPTP 600 G+PGP G G G G + P L E P Sbjct: 573 RGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGP 608 Score = 125 bits (314), Expect = 1e-28 Identities = 70/145 (48%), Positives = 80/145 (55%), Gaps = 9/145 (6%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 L G G +G G G GPPGP G G G +G+ G G G G IG GPPGE+G KG Sbjct: 1370 LPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKG 1429 Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPG 560 +G GP+GS G G+ G G SG GP GPP GLPGP GP G +G G PG G Sbjct: 1430 DRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP---GLPGPAGPKGAKGATG----PG--G 1480 Query: 561 PRGLPGLPGVPGMPGPKGPPGPPGP 585 P+G G+ G PG PGP G P P Sbjct: 1481 PKGEKGVQGPPGHPGPPGEVIQPLP 1505 Score = 107 bits (268), Expect = 3e-23 Identities = 69/171 (40%), Positives = 75/171 (43%), Gaps = 44/171 (25%) Query: 461 GPTGNKGQKGE----------KGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGS 510 GP G KG+KGE +G PGP GPAG GP G G PG G G +G G G Sbjct: 377 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 436 Query: 511 RGSPGKPGPQGPS-----------GDP-----------------------GPPGPPGKEG 536 GS G PGP G S GD GPPGP G G Sbjct: 437 PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTG 496 Query: 537 LPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 PGP G PG GL+G G+ G GPRG GL G PG G +G G G G Sbjct: 497 RPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARG 547 Score = 79.3 bits (194), Expect = 1e-14 Identities = 53/132 (40%), Positives = 63/132 (47%), Gaps = 21/132 (15%) Query: 462 PTGNKGQKGEKGEPGPPGPAG-------------ERGPIGPAGPPGERGGKGSKGSQGPK 508 PT ++ Q E GE G P G E +GPA E G+ + GP+ Sbjct: 322 PTADRFQAEEYGEGGTDPPEGPYDYTYGYGDDYREETELGPA-LSAETAHSGA-AAHGPR 379 Query: 509 GSRGSPGKPGPQGPSGDPGP--PGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPG 566 G +G G+P +PG GPPG EG G GPPG QG G VG+PG GP G G Sbjct: 380 GLKGEKGEPAVL----EPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAG 435 Query: 567 LPGVPGMPGPKG 578 LPG G PGP G Sbjct: 436 LPGSDGAPGPPG 447 >gi|48762934 alpha 2 type I collagen [Homo sapiens] Length = 1366 Score = 161 bits (408), Expect = 2e-39 Identities = 95/219 (43%), Positives = 108/219 (49%), Gaps = 53/219 (24%) Query: 443 GPPGPRGPRGDRGSQGPPGPTG------------------NKGQKGEKGEPGPPGPAGER 484 GP GPRG G+RG GP GP G KG KGE G GP GP G Sbjct: 703 GPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAA 762 Query: 485 GPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSG---DPGPPGPPGKEGLPGPQ 541 GP GP GPPG G +G G G G G+ G+ GP GPSG PGPPGP GKEGL GP+ Sbjct: 763 GPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPR 822 Query: 542 G---------------PPGFQGLQG------TVGEPGVPGPRGLPGLPGVPGMPGPKGPP 580 G PPGF G +G T G PG PGP+GL G PG+ G+PG +G Sbjct: 823 GDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGER 882 Query: 581 GPPGPSGAV---VPLALQNEP--------TPAPEDNGCP 608 G PG +GAV PL + P +P NG P Sbjct: 883 GLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAP 921 Score = 153 bits (386), Expect = 6e-37 Identities = 81/165 (49%), Positives = 92/165 (55%), Gaps = 12/165 (7%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERG------PIGPAGPPGER 496 G PG +G G G G PG TG +G GE+G G PGPAG RG P+GPAGP G Sbjct: 193 GAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSA 252 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G G G+ GPKG G+ G GP GP+G P G G GL GP GPPG G G G Sbjct: 253 GPPGFPGAPGPKGEIGAVGNAGPAGPAG---PRGEVGLPGLSGPVGPPGNPGANGLTGAK 309 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPA 601 G G LPG+ G PG+PGP+G PGP G +GA L EP PA Sbjct: 310 GAAG---LPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPA 351 Score = 153 bits (386), Expect = 6e-37 Identities = 88/183 (48%), Positives = 99/183 (54%), Gaps = 27/183 (14%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQ---KGEKGEPGPPGPAGERG---------PIGPA 490 G PG GPRG GS G GP G +G G G PGP GPAG RG P GP Sbjct: 442 GEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPT 501 Query: 491 GPPGERGGKG------SKGSQGPKGSRGSPGKPGP---QGPSGDPGPPGPPGKEGLPGPQ 541 G PG+ G KG ++G+ GP G+ G+ G PGP QG G+ GPPGPPG +GLPGP Sbjct: 502 GDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPS 561 Query: 542 GP------PGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQ 595 GP PG +GL G G PG GPRG G PG G GP GP G GPSG P + Sbjct: 562 GPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNK 621 Query: 596 NEP 598 EP Sbjct: 622 GEP 624 Score = 152 bits (384), Expect = 1e-36 Identities = 79/152 (51%), Positives = 87/152 (57%), Gaps = 3/152 (1%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPA---GPPGERG 497 L G G GP G+ G+QGPPGP G +G KGE+G PGPPG G GP GPA G PGERG Sbjct: 515 LAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERG 574 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557 G G GP G RG G PG G +G GP G G G PGP G G G+ G VG G Sbjct: 575 LHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAG 634 Query: 558 VPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAV 589 GP GLPG G G+PG KG G PG G + Sbjct: 635 PSGPSGLPGERGAAGIPGGKGEKGEPGLRGEI 666 Score = 151 bits (382), Expect = 2e-36 Identities = 88/191 (46%), Positives = 95/191 (49%), Gaps = 25/191 (13%) Query: 442 QGPPGP------RGPRGDRGSQGPPGPTGNKGQKGEKGEPGPP------GPAGERGPIGP 489 QGPPGP RGP G+ GS GPPGP G +G G +G PG GP G RG GP Sbjct: 369 QGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGP 428 Query: 490 AGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGL 549 AG G G G G G G RG PG PG GP+G GP G PG +G PGP GP G +G Sbjct: 429 AGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGE 488 Query: 550 QGTVGEPGVPGPRGLP---------GLPGVPGMPGP---KGPPGPPGPSGAVVPLALQNE 597 G +G PG GP G P GL G G PGP G GPPGP G Q Sbjct: 489 PGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGP 548 Query: 598 PTPAPEDNGCP 608 P P P G P Sbjct: 549 PGP-PGFQGLP 558 Score = 150 bits (380), Expect = 3e-36 Identities = 79/157 (50%), Positives = 85/157 (54%), Gaps = 9/157 (5%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 + GP G G G RG G PGP G+KG+ G KGEPG GP G GP G G G G G Sbjct: 329 IPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAG 388 Query: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPG 560 S G GP G RGSPG G G G G GPPG G GP G G G G GEPG+ G Sbjct: 389 SAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMG 448 Query: 561 PRGLPGLP---------GVPGMPGPKGPPGPPGPSGA 588 PRGLPG P G G+PG G PGP GP+GA Sbjct: 449 PRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGA 485 Score = 150 bits (379), Expect = 4e-36 Identities = 85/180 (47%), Positives = 94/180 (52%), Gaps = 30/180 (16%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG---------PAGP 492 +G GP G RG G G PG G G +G G PG GPAG+ GP+G P GP Sbjct: 423 RGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGP 482 Query: 493 PGERGGKGSKGSQGPKGSRGSPGK---------------PGPQGPSGDPGPPGPPGKE-- 535 G RG G+ G GPKG G PGK PGP G +G GPPGP G + Sbjct: 483 AGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGG 542 Query: 536 -GLPGPQGPPGFQGL---QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 G GP GPPGFQGL G GE G PG RGL G G+PG GP+G GPPG SGA P Sbjct: 543 KGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGP 602 Score = 150 bits (379), Expect = 4e-36 Identities = 79/156 (50%), Positives = 88/156 (56%), Gaps = 6/156 (3%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKG------QKGEKGEPGPPGPAGERGPIGPAGPPGE 495 QGPPGP+G +G +G QGPPGP G +G GE G+PG G GE G GPAGP GE Sbjct: 531 QGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGE 590 Query: 496 RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGE 555 RG G G+ GP G GS G GP GP G+ G PG G G GP GP G G +G G Sbjct: 591 RGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGI 650 Query: 556 PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 PG G +G PGL G G PG G G PG GA P Sbjct: 651 PGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGP 686 Score = 149 bits (377), Expect = 7e-36 Identities = 86/209 (41%), Positives = 99/209 (47%), Gaps = 40/209 (19%) Query: 433 QLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG---------- 482 Q ++ T+ +GP G RGPRG+RG GPPG G G G G PGPPGP G Sbjct: 23 QSLQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYD 82 Query: 483 ---------ERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGP-- 531 G +GP GPPG G G +G QGP G G PG+ GP G G GPPG Sbjct: 83 GKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAG 142 Query: 532 ----PGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGL------------PGLPGV---PG 572 PGK G PG +G G QG +G G PG+PG +G+ PG PGV PG Sbjct: 143 EDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPG 202 Query: 573 MPGPKGPPGPPGPSGAVVPLALQNEPTPA 601 PG G PG G G P PA Sbjct: 203 APGENGTPGQTGARGLPGERGRVGAPGPA 231 Score = 148 bits (374), Expect = 2e-35 Identities = 78/154 (50%), Positives = 86/154 (55%), Gaps = 9/154 (5%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGE------RGPIGPAGPPGER 496 G PGP G RG GS GP GP G G G G PG PGP GE GP GPAGP GE Sbjct: 226 GAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEV 285 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDP---GPPGPPGKEGLPGPQGPPGFQGLQGTV 553 G G G GP G+ G+ G G +G +G P G PG PG G+PGP G G G +G V Sbjct: 286 GLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLV 345 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 GEPG G +G G G PG GP+GPPGP G G Sbjct: 346 GEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEG 379 Score = 148 bits (374), Expect = 2e-35 Identities = 78/169 (46%), Positives = 91/169 (53%), Gaps = 24/169 (14%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PGP G G G++GPPG G+ G G GE G G G GP G G PG +G +G Sbjct: 892 GEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYP 951 Query: 503 GSQGPKGSRGSPGKPGPQGPSG------DPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G+ GP G+ G+PG GP GP+G + GP GP G G GP+GP G QG++G GEP Sbjct: 952 GNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEP 1011 Query: 557 GVPGPRGLPGL------------------PGVPGMPGPKGPPGPPGPSG 587 G GPRGLPGL G PG GP GP GP GPSG Sbjct: 1012 GEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSG 1060 Score = 148 bits (373), Expect = 2e-35 Identities = 75/155 (48%), Positives = 83/155 (53%), Gaps = 9/155 (5%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +G PG GP G G+ GP GP G G+ G +GE GP GP G G +GP GP G +G +G Sbjct: 948 RGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGD 1007 Query: 502 KGSQGPKGSRGSP---------GKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552 KG G KG RG P G PG G GD G PG G G GP GP G G G Sbjct: 1008 KGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGR 1067 Query: 553 VGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G PG GP G+ G G G GP GPPGPPGP G Sbjct: 1068 TGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPG 1102 Score = 147 bits (371), Expect = 3e-35 Identities = 71/145 (48%), Positives = 79/145 (54%), Gaps = 12/145 (8%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PGP G GDRG G GP G G +G GE G GPAG G GPAG G+ G KG + Sbjct: 682 GAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGER 741 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G++GPKG G G GP G +G GP GPPG G G GPPG G G G G PGP Sbjct: 742 GAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPS 801 Query: 563 GLPGLPGVPGMPGPKGPPGPPGPSG 587 G+ GPPGPPGP+G Sbjct: 802 GI------------SGPPGPPGPAG 814 Score = 145 bits (366), Expect = 1e-34 Identities = 82/176 (46%), Positives = 89/176 (50%), Gaps = 12/176 (6%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG---ERGGK 499 GP G G RG+ G+ GP GP G +G GE+GE GP GP G GP G AG PG ERG K Sbjct: 685 GPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAK 744 Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPG------PPGKEGLPGPQGPPGFQGLQGTV 553 G KG G G G G GP GP+G PGP G PPG G PG G G G G Sbjct: 745 GPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGIS 804 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPP 609 G PG PGP G GL G G +GP G G GAV P E P+ E P Sbjct: 805 GPPGPPGPAGKEGL---RGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGP 857 Score = 144 bits (364), Expect = 2e-34 Identities = 88/208 (42%), Positives = 97/208 (46%), Gaps = 34/208 (16%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGE---------RGPIGPAG 491 L GP GPRG RG G G GPTG G +G G PGP G GE GP GP+G Sbjct: 581 LPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSG 640 Query: 492 PPGER------GGKGSKGSQGPKGSRGSPGK------------PGPQGPSGDPGPPGPPG 533 PGER GGKG KG G +G G+PG+ PGP G +GD G G G Sbjct: 641 LPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAG 700 Query: 534 KEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPP------GPPGPSG 587 G GP+G PG +G G G G GP G G PG G G KGP GP GP G Sbjct: 701 PAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVG 760 Query: 588 AVVPLALQNEPTPA-PEDNGCPPHWKNF 614 A P P PA +G PP F Sbjct: 761 AAGPAGPNGPPGPAGSRGDGGPPGMTGF 788 Score = 144 bits (362), Expect = 4e-34 Identities = 81/190 (42%), Positives = 94/190 (49%), Gaps = 22/190 (11%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE---------------PGPPGPAGERGP 486 +G G GP G G+ GP GP G G G +G+ GPPGP+G GP Sbjct: 747 KGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGP 806 Query: 487 IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF 546 GP GP G+ G +G +G QGP G G G GP G +G+ GP G G G PG GP G Sbjct: 807 PGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGL 866 Query: 547 QGLQGTVGEPGVPGPRGLPGLPGVPGMPGP---KGPPGPPGPSGAVVPLALQNEPTPAPE 603 G G +G PG G RGLPG+ G G PGP GPPG GP GAV + P A Sbjct: 867 LGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGR 926 Query: 604 D----NGCPP 609 D N PP Sbjct: 927 DGNPGNDGPP 936 Score = 143 bits (360), Expect = 7e-34 Identities = 76/149 (51%), Positives = 85/149 (57%), Gaps = 9/149 (6%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GP G GPRG G+ G PGP G +G GE GEPG GPAG RGP AGPPG+ G G Sbjct: 91 GPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGP---AGPPGKAGEDGHP 147 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQ---GLQGTVGEPGVP 559 G G G R G GPQG G PG PG PG +G+ G G G + G G GEPG P Sbjct: 148 GKPGRPGER---GVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAP 204 Query: 560 GPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588 G G PG G G+PG +G G PGP+GA Sbjct: 205 GENGTPGQTGARGLPGERGRVGAPGPAGA 233 Score = 143 bits (360), Expect = 7e-34 Identities = 86/197 (43%), Positives = 95/197 (48%), Gaps = 45/197 (22%) Query: 443 GPPGPRGPRGD---RGSQGPPGPTGNKGQKG------------EKGEPGPPGPAGERGPI 487 GP GP GPRG+ G GP GP GN G G G PG PGP G GP+ Sbjct: 274 GPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPV 333 Query: 488 G---------------PAGPPGERGGKGSKGS---QGPKGSRGSPGKPGPQGPSGDPGPP 529 G PAG GE G KG GS QGP G G GK GP G +G GPP Sbjct: 334 GAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPP 393 Query: 530 GPPGKEGLPGPQGPPGFQGLQGTVGEP---------GVPGPRGLPGLPGVPGMPGPKGPP 580 GPPG G PG +G PG G G +G P GV GP G G PG PG+ GP+G P Sbjct: 394 GPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLP 453 Query: 581 GPP---GPSGAVVPLAL 594 G P GP+G P+ L Sbjct: 454 GSPGNIGPAGKEGPVGL 470 Score = 142 bits (359), Expect = 9e-34 Identities = 71/150 (47%), Positives = 85/150 (56%), Gaps = 6/150 (4%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG---PPGPAGERGPIGPAGPPGERG 497 + G PG G G+ G+ GPPG G G KGE+G PG P G AG GP GP GP G+ G Sbjct: 917 VNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHG 976 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557 +G G GP G G+ G GP GP G G G PG++ GP+G PG +G G G PG Sbjct: 977 NRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEK---GPRGLPGLKGHNGLQGLPG 1033 Query: 558 VPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 + G G G PG G GP+GP GP GP+G Sbjct: 1034 IAGHHGDQGAPGSVGPAGPRGPAGPSGPAG 1063 Score = 142 bits (357), Expect = 1e-33 Identities = 79/169 (46%), Positives = 89/169 (52%), Gaps = 18/169 (10%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP---IGPAGPPGERG 497 + GPPGP GP G G +GP G G G+ GE G GPPG AGE+GP G AGPPG G Sbjct: 803 ISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPG 862 Query: 498 GKG------------SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPG 545 +G S+G +G G G+ G+PGP G +G PG GPPG G PG G PG Sbjct: 863 PQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPG 922 Query: 546 FQGLQGTVGEPGVPGPRGLPGLPGVPGMP---GPKGPPGPPGPSGAVVP 591 G G G G PG G PG G G P GP G G PGP G V P Sbjct: 923 EAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGP 971 Score = 141 bits (355), Expect = 2e-33 Identities = 76/161 (47%), Positives = 85/161 (52%), Gaps = 15/161 (9%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGER---------GPIGPAGPP 493 GP GP GP G G G PG G KG+ G G GP GPAG R GP+GP G P Sbjct: 241 GPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNP 300 Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553 G G G+KG+ G G G+PG PGP+G G G G G GL G GP G +G G Sbjct: 301 GANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNK 360 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPK------GPPGPPGPSGA 588 GEPG GP+G PG G G GP GPPGPPG G+ Sbjct: 361 GEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGS 401 Score = 141 bits (355), Expect = 2e-33 Identities = 76/166 (45%), Positives = 85/166 (51%), Gaps = 9/166 (5%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE---PGPPGPAGERGP------IGPAGP 492 QGPPGP G +G G GP G G G++G GE PGP GP GERGP GP GP Sbjct: 546 QGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGP 605 Query: 493 PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552 G RG G G G KG G G G GPSG G PG G G+PG +G G GL+G Sbjct: 606 IGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGE 665 Query: 553 VGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598 +G PG G RG PG G PG G G G G +G P + P Sbjct: 666 IGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSP 711 Score = 140 bits (354), Expect = 3e-33 Identities = 79/170 (46%), Positives = 92/170 (54%), Gaps = 10/170 (5%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG------PPGPAGERGPIGPAGPPGER 496 GP G RG G+ G GP GPTG+ G+ G+KG G PGP G G GP GP G + Sbjct: 481 GPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQ 540 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 GGKG +G GP G +G PG GP G G PG G G+ GLPGP GP +G +G GE Sbjct: 541 GGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGP---RGERGPPGES 597 Query: 557 GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNG 606 G GP G G G G PGP G G PG GA V A + P+ P + G Sbjct: 598 GAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGA-VGTAGPSGPSGLPGERG 646 Score = 139 bits (351), Expect = 7e-33 Identities = 74/162 (45%), Positives = 82/162 (50%), Gaps = 3/162 (1%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PG RG G+ G GP GP G +G GE G GP GP G RGP GP GP G +G G Sbjct: 568 GKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVV 627 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G+ G G G G PG +G +G PG G G+ GL G G PG G +G G G PGP Sbjct: 628 GAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPA 687 Query: 563 GLPGLPGVPGMPGPKGPPGP---PGPSGAVVPLALQNEPTPA 601 G G G G GP GP GP PG G V P PA Sbjct: 688 GATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPA 729 Score = 139 bits (349), Expect = 1e-32 Identities = 75/164 (45%), Positives = 90/164 (54%), Gaps = 21/164 (12%) Query: 443 GPPG---PRGPRGDRGSQGPPGPTGNKG------------QKGEKGEPGPPGPAGERGPI 487 GPPG +GP G+ G+ GPPG G +G +GE+G PG G GE GP+ Sbjct: 838 GPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPL 897 Query: 488 GPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQ 547 G AGPPG RG G+ GS G G+ PG G G+PG GPPG++G PG +G G+ Sbjct: 898 GIAGPPGARGPPGAVGSPGVNGA------PGEAGRDGNPGNDGPPGRDGQPGHKGERGYP 951 Query: 548 GLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 G G VG G PGP G G G G G GP GP GP+GAV P Sbjct: 952 GNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGP 995 Score = 136 bits (343), Expect = 6e-32 Identities = 74/167 (44%), Positives = 83/167 (49%), Gaps = 21/167 (12%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G GP GP G G GPPGP G +G +G +G+ GP G GE G +GP G GE+G G Sbjct: 793 GRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEA 852 Query: 503 GSQGP------------------KGSRGSPGKPGPQGPSGDPGP---PGPPGKEGLPGPQ 541 G+ GP GSRG G PG G G+PGP GPPG G PG Sbjct: 853 GTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAV 912 Query: 542 GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588 G PG G G G G PG G PG G PG G +G PG GP GA Sbjct: 913 GSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGA 959 Score = 135 bits (340), Expect = 1e-31 Identities = 78/172 (45%), Positives = 87/172 (50%), Gaps = 24/172 (13%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGP------AGPPGE 495 QGP G G G G G GP G G+ GE G PG PG GERG +GP G PG Sbjct: 114 QGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGL 173 Query: 496 RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGK---EGLPGPQ------GPPGF 546 G KG +G G G +G PG PG +G G PG G PG+ GLPG + GP G Sbjct: 174 PGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGA 233 Query: 547 QGLQGTVGEPGVPGPRGLPGLPGVPGMPGPK---------GPPGPPGPSGAV 589 +G G+VG G GP G G PG PG PGPK GP GP GP G V Sbjct: 234 RGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEV 285 Score = 132 bits (331), Expect = 2e-30 Identities = 75/171 (43%), Positives = 85/171 (49%), Gaps = 12/171 (7%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +GPPG G G +G QGP G G GQ G G GP GP G+ G G G PG G +G Sbjct: 99 RGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGV 158 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGP 561 G QG +G G+PG PG +G G G G G+ G PG +G PG G GT PG G Sbjct: 159 VGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGT---PGQTGA 215 Query: 562 RGLPGLPGVPGMPGPK---------GPPGPPGPSGAVVPLALQNEPTPAPE 603 RGLPG G G PGP GP GP GP G+ P P P E Sbjct: 216 RGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGE 266 Score = 107 bits (267), Expect = 4e-23 Identities = 56/122 (45%), Positives = 66/122 (54%), Gaps = 18/122 (14%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKG---------------EKGEPGPPGPAGERGP 486 +GP GP+G RGD+G G GP G G KG ++G PG GPAG RGP Sbjct: 996 RGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGP 1055 Query: 487 IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF 546 GP+GP G+ G G G+ GP G RG G GP GP PGPPGPPG G+ G G+ Sbjct: 1056 AGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGP---PGPPGPPGPPGVSGGGYDFGY 1112 Query: 547 QG 548 G Sbjct: 1113 DG 1114 Score = 88.2 bits (217), Expect = 3e-17 Identities = 46/102 (45%), Positives = 52/102 (50%), Gaps = 18/102 (17%) Query: 435 IKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG 494 +K LQG PG G GD+G+ G G PAG RGP GP+GP G Sbjct: 1022 LKGHNGLQGLPGIAGHHGDQGAPGSVG------------------PAGPRGPAGPSGPAG 1063 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG 536 + G G G+ GP G RG G GP GP G PGPPGPPG G Sbjct: 1064 KDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSG 1105 Score = 87.8 bits (216), Expect = 3e-17 Identities = 50/113 (44%), Positives = 55/113 (48%), Gaps = 7/113 (6%) Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQ----GLQGTVG 554 KG G +GP+G RG PG PG G G GPPGPPG G PG G Q G+ G Sbjct: 32 KGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPG 91 Query: 555 EPGVPGPRGLPGLPGVPG---MPGPKGPPGPPGPSGAVVPLALQNEPTPAPED 604 G+ GPRG PG G PG GP G PG PG +G P A ED Sbjct: 92 PMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGED 144 Score = 35.8 bits (81), Expect = 0.15 Identities = 16/36 (44%), Positives = 20/36 (55%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG 476 ++GP G +GP G G GPPGP G G + G G Sbjct: 1079 IRGPQGHQGPAGPPGPPGPPGPPGVSGGGYDFGYDG 1114 >gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] Length = 1860 Score = 161 bits (407), Expect = 2e-39 Identities = 80/154 (51%), Positives = 92/154 (59%), Gaps = 3/154 (1%) Query: 438 FTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERG 497 F L G PG G +GDRG GPPG G KG G PG PG G G GP GPPG RG Sbjct: 998 FIGLVGEPGIVGEKGDRGMMGPPGV---PGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRG 1054 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557 G +G++G +G RG G G QG G GPPGP G+ G PG QG G +G G+ G PG Sbjct: 1055 PPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPG 1114 Query: 558 VPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 +PGP G PG G+PG PGP+GP GP GP G + P Sbjct: 1115 IPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGP 1148 Score = 154 bits (389), Expect = 3e-37 Identities = 90/214 (42%), Positives = 102/214 (47%), Gaps = 54/214 (25%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQ---------------KGEKGEPGPPGPAGERG 485 L GP G GP GD G GPPG G +GQ KGE G+PG PGP GE+G Sbjct: 935 LPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQG 994 Query: 486 PIG------------------PAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPG 527 +G GPPG G KGS G G G G+PG+PGPQGP G G Sbjct: 995 FMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRG 1054 Query: 528 PPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPG---------------VPG 572 PPG G +G GP+GP G G QG+ G G PGP+G PG PG PG Sbjct: 1055 PPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPG 1114 Query: 573 MPGPKGP------PGPPGPSGAVVPLALQNEPTP 600 +PGP GP PG PGP G P+ E P Sbjct: 1115 IPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGP 1148 Score = 152 bits (383), Expect = 1e-36 Identities = 75/152 (49%), Positives = 91/152 (59%), Gaps = 6/152 (3%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGPPGERGG 498 +GPPG RG +G RG +GP GP G +G +G KG PGP PG G++G G G G RG Sbjct: 1053 RGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGF 1112 Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF---QGLQGTVGE 555 G G GP G++G PG+PGPQGP G GPPG G +G PG G PG G++G +G Sbjct: 1113 PGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGP 1172 Query: 556 PGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G PG +GL G G PG+ G GP GP G G Sbjct: 1173 LGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKG 1204 Score = 152 bits (383), Expect = 1e-36 Identities = 77/154 (50%), Positives = 93/154 (60%), Gaps = 9/154 (5%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GPPG RGP GDRG +G PG G GQ+G +G G PG G+ G GP G PG +G KG++ Sbjct: 1343 GPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAE 1402 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF---------QGLQGTV 553 G +G +G G+PG+ G QG G PGP G G++GL G GP G QG QG Sbjct: 1403 GPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDD 1462 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G+PG GP G G PGV G+PG +GPPG G SG Sbjct: 1463 GDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESG 1496 Score = 151 bits (381), Expect = 2e-36 Identities = 75/159 (47%), Positives = 92/159 (57%), Gaps = 12/159 (7%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG---PPGPAGERGPIGPAGPPGERG 497 + GPPG GP+G G G PG G G+ G +G PG PPG G +G GP GP G G Sbjct: 1016 MMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAG 1075 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGL-------- 549 +GS+G +GP G +G PG+PG QG +G+ G G G G+PGP GPPG +GL Sbjct: 1076 EQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQG 1135 Query: 550 -QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 QG +G PG GP+G PG G PG+PG G G GP G Sbjct: 1136 PQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLG 1174 Score = 150 bits (379), Expect = 4e-36 Identities = 83/178 (46%), Positives = 96/178 (53%), Gaps = 15/178 (8%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGE---KGEPGPPGPAGERGPIGPAGPPGERGG 498 QGP GP GP G+ G +GPPG G G GE KG+ GP G GE+G IG G PG G Sbjct: 1134 QGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGD 1193 Query: 499 KGSKGSQGPKGSRGSPG------KPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552 G G G KG RG PG + G +G G+ GPPGPPG G+ GP+G G QG +G Sbjct: 1194 SGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGR 1253 Query: 553 VGEPGVP------GPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPED 604 G G G G+PG PG PG PGPKG G GP+GA + Q EP A D Sbjct: 1254 TGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYD 1311 Score = 149 bits (377), Expect = 7e-36 Identities = 81/167 (48%), Positives = 92/167 (55%), Gaps = 17/167 (10%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GP GP G RG+ G G PG G G KGE G PG GP G+RG G G PG +G GSK Sbjct: 1466 GPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSK 1525 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G G G G PG G GP G PPG G +G+ GP+GPPG G +G VG G+ GP Sbjct: 1526 GQPGDSGEMGFPGMAGLFGPKG---PPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPS 1582 Query: 563 GLP------------GLPGVPGMPGPKGPPGPPGPSGAVVPLALQNE 597 GLP GL G G PGP+G PGPPGP G P+ LQ + Sbjct: 1583 GLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGG--PIQLQQD 1627 Score = 149 bits (376), Expect = 9e-36 Identities = 84/180 (46%), Positives = 100/180 (55%), Gaps = 19/180 (10%) Query: 443 GPPGPRGPRGDRGSQGPPG---PTGNKGQKGEKGEPGPPGPAGE------RGPIGPAGPP 493 G PG G G+ G QGPPG P G +G KG +G GP GPAGE +GP GP G P Sbjct: 1033 GMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRP 1092 Query: 494 GERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQ--- 550 G G +G G +G GSRG PG PGP GP G G PG PG +G GP GPPG G + Sbjct: 1093 GRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPP 1152 Query: 551 GTVGEPGVPGPRGLP------GLPGVPGMPGPKGPPGPPGPSGAVVPLALQNE-PTPAPE 603 G VGEPG+PG G+ G PG G+ G +G PG G SG + P L+ + P P+ Sbjct: 1153 GAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPD 1212 Score = 149 bits (375), Expect = 1e-35 Identities = 80/169 (47%), Positives = 91/169 (53%), Gaps = 16/169 (9%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 GP GP G +GDRG GP G G KGQ+G GE GPPGP G G GP G+ G +G K Sbjct: 1195 GPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGV---RGPEGKSGKQGEK 1251 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPR 562 G G KG++G G+ G G GDPGPPG PG +G G GP G G G GEPG+ G Sbjct: 1252 GRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYD 1311 Query: 563 GLPGLPGVPGMPGPK-------------GPPGPPGPSGAVVPLALQNEP 598 G G+ G G PGPK GPPGPPG G V + EP Sbjct: 1312 GHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEP 1360 Score = 148 bits (373), Expect = 2e-35 Identities = 77/157 (49%), Positives = 90/157 (57%), Gaps = 12/157 (7%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PGP GP G G GPPG G +G KG+ G G PGP G+ GP G GP G G G + Sbjct: 901 GFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLE 960 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKE------GLPGPQGPPGFQGLQGTVGEP 556 G G KG G PG G +G GDPG PGP G++ GL G G G +G +G +G P Sbjct: 961 GQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPP 1020 Query: 557 GVPGPR------GLPGLPGVPGMPGPKGPPGPPGPSG 587 GVPGP+ G+PG G PG PGP+GPPG GP G Sbjct: 1021 GVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPG 1057 Score = 146 bits (369), Expect = 6e-35 Identities = 82/190 (43%), Positives = 97/190 (51%), Gaps = 25/190 (13%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPA---GPPGERGG 498 QG G +G G G++G PGP G G KG G PGPPGP G G IGP GP G +G Sbjct: 870 QGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGK 929 Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGL------------------PGP 540 G++G GP+G G G GP GP G PG G PG++G PGP Sbjct: 930 PGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGP 989 Query: 541 QGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP 600 G GF G G VGEPG+ G +G G+ G PG+PGPKG G PG G + EP P Sbjct: 990 VGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGG---MGTPGEPGP 1046 Query: 601 -APEDNGCPP 609 P + PP Sbjct: 1047 QGPPGSRGPP 1056 Score = 146 bits (368), Expect = 8e-35 Identities = 82/168 (48%), Positives = 96/168 (57%), Gaps = 21/168 (12%) Query: 438 FTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERG 497 F +L GPP GP+GD G GPPG G G G +G GPPGP G G GP G G++G Sbjct: 620 FPLLMGPP---GPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKG 676 Query: 498 ------GK---GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF-- 546 GK G+KG G G G+PG PG +G G PGP G PG++G PGP+G PG Sbjct: 677 DPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKG 736 Query: 547 ----QGLQGTVGEPGVPGPR---GLPGLPGVPGMPGPKGPPGPPGPSG 587 QGL G VG+PG G R GLPGL G+PG G +G PG PG G Sbjct: 737 YPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRG 784 Score = 145 bits (367), Expect = 1e-34 Identities = 85/181 (46%), Positives = 94/181 (51%), Gaps = 18/181 (9%) Query: 441 LQGPPGPRGPRGDRGSQGP---PGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERG 497 L GPPG G GD G GP PGP G KG G GEPG G GE+G G +G PG +G Sbjct: 812 LPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQG 871 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557 KGS+G G G+RG PG G G G G PGPPG EG PG GPPG G +G G+PG Sbjct: 872 DKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPG 931 Query: 558 ---VPGPRGL------------PGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAP 602 +PGPRG PG PG+ G PG KG PG PG G P P Sbjct: 932 ARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVG 991 Query: 603 E 603 E Sbjct: 992 E 992 Score = 144 bits (362), Expect = 4e-34 Identities = 80/164 (48%), Positives = 92/164 (56%), Gaps = 6/164 (3%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPG-PPGPA--GERGPIGPAGPPGERG 497 L G PG RGPRG G G PG G G KG+KG+PG PG A G +G +G G G G Sbjct: 644 LPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPG 703 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP- 556 G KG +G G G PG+ G GP G PG G PG++GLPGP G PG +G +G +G P Sbjct: 704 PPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPG 763 Query: 557 --GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEP 598 G+PG G GLPGVPG G G PG PG G P L P Sbjct: 764 LFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNP 807 Score = 142 bits (359), Expect = 9e-34 Identities = 80/168 (47%), Positives = 91/168 (54%), Gaps = 27/168 (16%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGE---------------------KGEPGPPG 479 + G GPRGP G G+ G PGP G KGQKG+ G PGPPG Sbjct: 647 IPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPG 706 Query: 480 PAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPG 539 G +G GPAG PGE+G G +GS G KG PG+ G GP GDPGP G G GLPG Sbjct: 707 RKGHKGYPGPAGHPGEQGQPGPEGSPGAKGY---PGRQGLPGPVGDPGPKGSRGYIGLPG 763 Query: 540 PQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G PG G +G PGVPG RG G+PG PG+ G +GPPG G G Sbjct: 764 LFGLPGSDGERGL---PGVPGKRGKMGMPGFPGVFGERGPPGLDGNPG 808 Score = 141 bits (355), Expect = 2e-33 Identities = 85/199 (42%), Positives = 98/199 (49%), Gaps = 29/199 (14%) Query: 428 DSKHGQLIKNFTILQ-GPPGP------RGPRGDRGSQGPPGPTGNKGQKG------EKGE 474 D +HG+ + + + GPPGP RGP G G QG G TG KG KG E G Sbjct: 1212 DGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGV 1271 Query: 475 P------GPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGD--- 525 P G PGP G RG +GP G PG G +G G G G +G G GP GP G+ Sbjct: 1272 PGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGE 1331 Query: 526 -------PGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKG 578 GPPGPPG G G +G G G G G+ GV G RG PG G PG PGP+G Sbjct: 1332 QGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRG 1391 Query: 579 PPGPPGPSGAVVPLALQNE 597 PGP G GA P Q + Sbjct: 1392 WPGPKGSKGAEGPKGKQGK 1410 Score = 140 bits (354), Expect = 3e-33 Identities = 74/160 (46%), Positives = 89/160 (55%), Gaps = 9/160 (5%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGER---GPIGPAGPPGERG 497 L+GPPGP+G G G QG G G+ G +G G PGP GP G + G GP GP G G Sbjct: 1082 LKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIG 1141 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPG 557 G G +GP G+ G PG PG G GD GP G PG++GL G +G PG +G G +G G Sbjct: 1142 PPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDG 1201 Query: 558 V------PGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 + PGP G G G G+ G GPPGPPG +G P Sbjct: 1202 LKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGP 1241 Score = 140 bits (353), Expect = 4e-33 Identities = 76/159 (47%), Positives = 88/159 (55%), Gaps = 12/159 (7%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 L+G PG +G G G +G PGP G+KG +G KG+ G G G RG G G PG RG G Sbjct: 1374 LRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVG 1433 Query: 501 SKGSQGPKGSRGSPGK------PGPQGPSGDPGPPGP------PGKEGLPGPQGPPGFQG 548 +G +G G G PG+ G QG GDPGP GP PG GLPG QGPPGF+G Sbjct: 1434 RQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKG 1493 Query: 549 LQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G G+ G PG RG G G+PG G G G PG SG Sbjct: 1494 ESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSG 1532 Score = 139 bits (351), Expect = 7e-33 Identities = 75/166 (45%), Positives = 89/166 (53%), Gaps = 7/166 (4%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGE-------PGPPGPAGERGPIGPAGPPG 494 QG PG G G +G GP GP G KG+KGE+GE PGPPG G G G G PG Sbjct: 1302 QGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPG 1361 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVG 554 + G G +G QG +G G G+PG GP G PGP G G EG G QG G G +G G Sbjct: 1362 DPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQG 1421 Query: 555 EPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP 600 G+PGPRG+ G G+ G+ GP G PG G +G +P P Sbjct: 1422 LQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGP 1467 Score = 137 bits (344), Expect = 5e-32 Identities = 77/178 (43%), Positives = 90/178 (50%), Gaps = 27/178 (15%) Query: 441 LQGPPGPRGPRGDRG------SQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG 494 L G PG RG G G +GPPG GN G+ G G PG PG G+ G +GP G PG Sbjct: 776 LPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPG 835 Query: 495 ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDP---------GPPGPPGKEGLPGP----- 540 +G KG GS G G +G G+ G G SGDP G PG PG G PGP Sbjct: 836 PKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVG 895 Query: 541 -------QGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 GPPG +G G +G PG GP G+ G PG G+PGP+G GP G G + P Sbjct: 896 DKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGP 953 Score = 135 bits (340), Expect = 1e-31 Identities = 75/155 (48%), Positives = 86/155 (55%), Gaps = 9/155 (5%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP---PGPAGERGPIGPAGP---PGE 495 +G PGP G G++G GP G G KG G +G PGP PGP G RG IG G PG Sbjct: 711 KGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGS 770 Query: 496 RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGE 555 G +G G G +G G PG PG G G PG G PG+ GLPGP G PG G G +G Sbjct: 771 DGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGP 830 Query: 556 PGVPGPRGLPGL---PGVPGMPGPKGPPGPPGPSG 587 G PGP+G+ GL G PG+ G KG G PG SG Sbjct: 831 IGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSG 865 Score = 135 bits (340), Expect = 1e-31 Identities = 87/204 (42%), Positives = 100/204 (49%), Gaps = 35/204 (17%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPG-------- 494 GP G +G G +G QG G G +G +G +G PGP G G +G G AGP G Sbjct: 1394 GPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQA 1453 Query: 495 ----ERGGKGSKGSQGPKGSRGSP---GKPGPQGP------SGDPGPPGPPGKE------ 535 E+G G G GP G RG+P G PG QGP SG PG GPPGK Sbjct: 1454 GQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRT 1513 Query: 536 GLPGPQGPPGFQGLQGTVGEPGVP------GPRGLPGLPGVPGMPGPKGPPGPPGPSGAV 589 GLPG QG PG +G G GE G P GP+G PG G G+ GP+GPPG G G V Sbjct: 1514 GLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIV 1573 Query: 590 VPLA-LQNEPTPAPE-DNGCPPHW 611 PL L P P+ D G W Sbjct: 1574 GPLGILGPSGLPGPKGDKGSRGDW 1597 Score = 132 bits (333), Expect = 9e-31 Identities = 82/185 (44%), Positives = 90/185 (48%), Gaps = 27/185 (14%) Query: 441 LQGPPGPRGPRGD------------RGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG 488 L GPPG +G +GD +G G PG +GN G G KG G PGPAG G G Sbjct: 665 LPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQG 724 Query: 489 PAGPPGERGGKGSKGSQ---------GPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPG 539 GP G G KG G Q GPKGSRG G PG G G G G PG G G Sbjct: 725 QPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRG 784 Query: 540 PQGPPGFQGLQGTVGEPGV---PGPRGLPGLPGVPGMPGPKGPPGP---PGPSGAVVPLA 593 G PGF G+ G G PG+ PG GLPG PGVPG+ G G GP PGP G + Sbjct: 785 KMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMG 844 Query: 594 LQNEP 598 EP Sbjct: 845 SVGEP 849 Score = 129 bits (325), Expect = 8e-30 Identities = 76/168 (45%), Positives = 85/168 (50%), Gaps = 21/168 (12%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAG------------ERGP-- 486 L GP G GP+G RG G PG G G GE+G PG PG G ERGP Sbjct: 743 LPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPG 802 Query: 487 -------IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPG 539 +G GPPG G G G GP G G G G G G+PG G G++G+PG Sbjct: 803 LDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPG 862 Query: 540 PQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587 G PGFQG +G+ G PG PG RG PG G G G G PGPPGP G Sbjct: 863 VSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEG 910 Score = 107 bits (266), Expect = 5e-23 Identities = 59/126 (46%), Positives = 66/126 (52%), Gaps = 5/126 (3%) Query: 476 GPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPG-PPGK 534 GPPGP G+ G GP G PG G G++G +GP G G+PG PGP G G G PG PGK Sbjct: 625 GPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGK 684 Query: 535 EGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLAL 594 G G GL G G PG PG +G G PG G PG +G PGP G GA Sbjct: 685 ----AHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGR 740 Query: 595 QNEPTP 600 Q P P Sbjct: 741 QGLPGP 746 Score = 79.7 bits (195), Expect = 9e-15 Identities = 46/103 (44%), Positives = 49/103 (47%), Gaps = 24/103 (23%) Query: 509 GSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGP------- 561 GS P GP GP GD G PGPPG GLPG G G +G G G PG+PGP Sbjct: 616 GSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQK 675 Query: 562 -----------------RGLPGLPGVPGMPGPKGPPGPPGPSG 587 GLPGL G PG PG KG G PGP+G Sbjct: 676 GDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAG 718 Score = 78.6 bits (192), Expect = 2e-14 Identities = 44/101 (43%), Positives = 53/101 (52%), Gaps = 21/101 (20%) Query: 442 QGPPGPRGPRGDRGSQG---------PPGPTGNKGQKGEKGEPGPPGPAGERGPIGP--- 489 QG PG +G GD G G P GP G+ G KG +G GPPG G+ G +GP Sbjct: 1519 QGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGI 1578 Query: 490 ---AGPPGERGGKGSKGS------QGPKGSRGSPGKPGPQG 521 +G PG +G KGS+G +GP G RG PG PGP G Sbjct: 1579 LGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPG 1619 Score = 71.2 bits (173), Expect = 3e-12 Identities = 64/195 (32%), Positives = 78/195 (40%), Gaps = 51/195 (26%) Query: 438 FTILQGPPGPRGPRGDRGSQGP----PGPTGNKGQKGEKGEPGP-PGPAGERGPIGP--- 489 FT L P P P R ++ P P +G + P P P G + PIG Sbjct: 484 FTALSSSPAPT-PGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEAS 542 Query: 490 --AGPPGE-------RGGKGSKGSQ-GPKGSRGSPGKPGP-------------QGPSGDP 526 AGP R GK ++ +R SP +P P Q S P Sbjct: 543 KKAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSP 602 Query: 527 GPPGP-------PGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGP 579 P G P GPPG +G + G+PGP GLPGLPG+PG GP+GP Sbjct: 603 RPTSSGYSIFHLAGSTPFPLLMGPPGPKG------DCGLPGPPGLPGLPGIPGARGPRGP 656 Query: 580 PGP------PGPSGA 588 PGP PGP GA Sbjct: 657 PGPYGNPGLPGPPGA 671 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 160 bits (406), Expect = 3e-39 Identities = 91/195 (46%), Positives = 103/195 (52%), Gaps = 28/195 (14%) Query: 438 FTILQGPPGP--------RGPRGDRGSQGPPG---PTGNKGQKGEKGEPGPPGPAGERGP 486 F +QGPPGP GP+G+ G QGPPG PTG +G G +G PG PG G +G Sbjct: 1230 FPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGE 1289 Query: 487 IGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGF 546 G G PG G G KG QGP G +G+PG+PG G GDPG PG PG G+ GP G PG Sbjct: 1290 KGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGS 1349 Query: 547 QGLQGTVGEPGVPGPRGLP-------------GLPGVPGMPGPKGPPGPPGPSGAVVPLA 593 G +G G G PGP GLP G PG+PG PG KG PGP GP G P Sbjct: 1350 AGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTG 1409 Query: 594 LQNEPTPAPEDNGCP 608 P P NG P Sbjct: 1410 ----PPGDPGRNGLP 1420 Score = 157 bits (396), Expect = 4e-38 Identities = 85/173 (49%), Positives = 95/173 (54%), Gaps = 14/173 (8%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +G PG G G G GP GP G +GQKG+ G PGPPGP G RGP G G PG G G Sbjct: 50 RGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGM 109 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG---------LQGT 552 G G G +G PG G +G G PG PG PG +G PGP G PG +G L G Sbjct: 110 PGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGP 169 Query: 553 VGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDN 605 G PG PGP G+ GLPG G+PGP GPPGPPG G P L P P+ N Sbjct: 170 KGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGL-----PGPKGN 217 Score = 155 bits (393), Expect = 1e-37 Identities = 85/184 (46%), Positives = 99/184 (53%), Gaps = 23/184 (12%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PG GP+G+ G G PG G KG G+ G PG PG G +G G G PG G G K Sbjct: 1074 GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPK 1133 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV--PG 560 G GP G+ G PG+PGP G G PG PGPPG++G PG G PG G +G G+PG PG Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG 1193 Query: 561 PRGLPGL------------PGVPGMPGPKGPP---------GPPGPSGAVVPLALQNEPT 599 P GLPGL PG PG+PGPKG P GPPGP G+ P + Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGN 1253 Query: 600 PAPE 603 P P+ Sbjct: 1254 PGPQ 1257 Score = 154 bits (388), Expect = 4e-37 Identities = 87/177 (49%), Positives = 95/177 (53%), Gaps = 15/177 (8%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 LQG PG G G +G G PG G G KG G PG GP GE G IGP GPPG G G Sbjct: 1313 LQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSG 1372 Query: 501 S----KGSQGPKGSRGSPGK---PGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553 KG GP G G PG PGPQGP G PGP GPPG PG G PGF G G Sbjct: 1373 QSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGD---PGRNGLPGFDGAGGRK 1429 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAV--VPLALQNEPTPAPEDNGCP 608 G+PG+PG G GL G PG G +GPPGPPG S + ++ T AP+ CP Sbjct: 1430 GDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQ---CP 1483 Score = 153 bits (387), Expect = 5e-37 Identities = 87/173 (50%), Positives = 94/173 (54%), Gaps = 14/173 (8%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +GPPGPRG +GD G GPPGP G +G G G PG PG G G G GP G G G+ Sbjct: 68 EGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGT 127 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGK---EGLPGPQG------PPGFQGLQGT 552 KG +G GS G PG GP GP G PG G PG LPGP+G PPG QGL G Sbjct: 128 KGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGP 187 Query: 553 VGEP---GVPGPRGLPGLPGVPGMPGPKGPPGP--PGPSGAVVPLALQNEPTP 600 G P G PGP GL G PG PG+PGPKG G GP G LQ P P Sbjct: 188 TGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 240 Score = 152 bits (384), Expect = 1e-36 Identities = 85/177 (48%), Positives = 94/177 (53%), Gaps = 26/177 (14%) Query: 441 LQGPPGPRGP------------RGDRGSQGPPG---PTGNKGQKGEKGEPGPPGPA---- 481 + GPPGP GP +GD G QG PG PTG KG KGE G PGPPGP Sbjct: 900 MMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNL 959 Query: 482 ----GERGPIGPAGPPGERGGKGSKGSQGPKGS---RGSPGKPGPQGPSGDPGPPGPPGK 534 GE+G G G PG G KG +G G G G PG PGP GP G+PG PG PG Sbjct: 960 LGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGL 1019 Query: 535 EGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 G PG +G G G G G G PGP G+PG PG PG+PG KG G PG S +P Sbjct: 1020 IGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLP 1076 Score = 151 bits (382), Expect = 2e-36 Identities = 83/173 (47%), Positives = 96/173 (55%), Gaps = 11/173 (6%) Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGE 495 K + L G PG G G G GPPGP GN G G+PG GP G +G IG G PG Sbjct: 981 KGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGL---PGQPGLIGPPGLKGTIGDMGFPGP 1037 Query: 496 RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDP-----GPPGPPGKEGLPGPQGPPGFQGLQ 550 +G +G G G G GSPG PG +G GDP G PG PG +G PG G PG G++ Sbjct: 1038 QGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIK 1097 Query: 551 GTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP---LALQNEPTP 600 G+VG+PG+PG G PG G PG+PG G PGPPGP G P L EP P Sbjct: 1098 GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGP 1150 Score = 150 bits (380), Expect = 3e-36 Identities = 86/183 (46%), Positives = 94/183 (51%), Gaps = 27/183 (14%) Query: 443 GPPGPRGPRG--DRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG--PAGPPGERGG 498 G PGP GP G G QGPPGP G G G+ G G PG G+ GP G GPPGERG Sbjct: 805 GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGS 864 Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDP---------GPPGPPGKEGLPGPQGPPGFQGL 549 G G+ GP G GSPG PG G SG P GPPGPPG G+PG G PG +G Sbjct: 865 PGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924 Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGP--------------PGPPGPSGAVVPLALQ 595 G G+PG+PGP G G G PG+PGP GP PG PG G P Q Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQ 984 Query: 596 NEP 598 P Sbjct: 985 GLP 987 Score = 150 bits (379), Expect = 4e-36 Identities = 89/197 (45%), Positives = 99/197 (50%), Gaps = 45/197 (22%) Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKG-----EPGPPGPAGERGPIGPA 490 K F + GPPG G G G +GPPGP G G KGE G PGPPG G +G +GP Sbjct: 715 KGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPK 774 Query: 491 G------PPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPG--PPGPPGKEGLPGPQG 542 G PPG G G G GPKG G G+PGP GP G PG GPPG G+PGP G Sbjct: 775 GDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIG 834 Query: 543 PPGFQGLQGTVGEPG-----VPGP---RGLPGLPGVPG---------MPGP--------- 576 PG G+ G G+PG VPGP RG PG+PG PG +PG Sbjct: 835 QPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGT 894 Query: 577 ------KGPPGPPGPSG 587 GPPGPPGP G Sbjct: 895 KGEMGMMGPPGPPGPLG 911 Score = 148 bits (373), Expect = 2e-35 Identities = 92/209 (44%), Positives = 96/209 (45%), Gaps = 55/209 (26%) Query: 438 FTILQGPPGPRGPRGDRGSQGP------PGPTGNKGQKGEKGEPGPPGPAGERGPIGPAG 491 F LQGPPGP G G +G G PGP GN G G G G PGP G GPIGP G Sbjct: 139 FPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPG 198 Query: 492 PPGERGGKGSKGS-----------QGPKGSRGSPGKPGPQGPSG---------------- 524 PPG G G G QGPKG +G G GP GP G Sbjct: 199 PPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKG 258 Query: 525 ------DPGPPGPPGKEGLPGP----------QGPPGFQGLQGTVGEPGVPGPRGLPGLP 568 D GPPGPPG G PGP QG PG +G G GE G PG GLPG P Sbjct: 259 DQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDP 318 Query: 569 GVPGMPG------PKGPPGPPGPSGAVVP 591 G PG PG KG GPPGP G V+P Sbjct: 319 GYPGEPGRDGEKGQKGDTGPPGPPGLVIP 347 Score = 147 bits (370), Expect = 5e-35 Identities = 86/172 (50%), Positives = 94/172 (54%), Gaps = 12/172 (6%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQ---KGEKGEPGPPGPAGERGPIGPAGPP--GERG 497 G PG G G G G PGP G G KGE+G PG PG G G IGP GPP G G Sbjct: 570 GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG 629 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSG----DPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553 G KG QG G+ G PG PGP+G G PG PG PG G G G PG GL G Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689 Query: 554 GEPGVPGPRGLPGLPGV--PGMPGPKGPPGPPGPSGAV-VPLALQNEPTPAP 602 G PG+PG +G PG+PG+ PG PGPKG PG PGP GA P + E P P Sbjct: 690 GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGP 741 Score = 147 bits (370), Expect = 5e-35 Identities = 87/198 (43%), Positives = 103/198 (52%), Gaps = 37/198 (18%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPT-----GNKGQKGEKGEPGPPGPAGERGPIGPAGPPGE 495 L GP G +G +G+ G GPPGP G+KG+KGE G PG PG +G +G G G PG+ Sbjct: 933 LPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQ 992 Query: 496 RGGKGSKGSQGPKGSRGSPGKPG---------------------PQGPSGDPGP---PGP 531 G G G GP G +G+PG PG PQG G PGP PG Sbjct: 993 PGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQ 1052 Query: 532 PGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGP------PGPPGP 585 PG GLPG +G G G+ ++G PG+PGP+G PGLPG PG PG KG PG PG Sbjct: 1053 PGSPGLPGQKGDKGDPGI-SSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGT 1111 Query: 586 SGAVVPLALQNEP-TPAP 602 GA L P TP P Sbjct: 1112 PGAKGQPGLPGFPGTPGP 1129 Score = 145 bits (366), Expect = 1e-34 Identities = 90/221 (40%), Positives = 102/221 (46%), Gaps = 54/221 (24%) Query: 441 LQGPPGPR---GPRGDRGSQGP-----PGPTGNKGQKGEKGEPGPPGPAGERGP------ 486 + GPPGP G RG +G +GP PGP G GQ G G PGPPGPAG P Sbjct: 392 VMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEIC 451 Query: 487 -IGPAGPPGERGGKGSKGSQGPKGSRG-------SPGKPGPQGPSGDPGPPGPPGKEGLP 538 GP GPPG G KG +G QG KG +G G GP G G PG PGPPG G P Sbjct: 452 EPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFP 511 Query: 539 GPQ---------GPPGFQGLQGTVGEPGVPGPR----------------------GLPGL 567 G + GP G G+ G G PG PG + G PGL Sbjct: 512 GQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGL 571 Query: 568 PGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 PG+PG PG G PG PGP G + + E P P + G P Sbjct: 572 PGLPGTPGQDGLPGLPGPKGEPGGITFKGERGP-PGNPGLP 611 Score = 145 bits (365), Expect = 2e-34 Identities = 90/194 (46%), Positives = 96/194 (49%), Gaps = 27/194 (13%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 L G PG +G G G G PGP G KG G G PG PG G G GP GPPG G KG Sbjct: 691 LPGIPGSKGEPGIPGI-GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG 749 Query: 501 SKGSQ--GPKGSRGSPGKPGPQGPSGD---PGPPGPPGKEGL---------------PGP 540 G GP G G PG G GP GD PGPPGPPG+ GL PGP Sbjct: 750 EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGP 809 Query: 541 QGPPGFQGL--QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPG--PPGPSGAVVPLALQN 596 GPPG G+ QG G PG+PGP G PGL G+PG G GPPG PGP G + Sbjct: 810 MGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPG 869 Query: 597 EPTP--APEDNGCP 608 P P P G P Sbjct: 870 APGPIGPPGSPGLP 883 Score = 144 bits (364), Expect = 2e-34 Identities = 84/182 (46%), Positives = 98/182 (53%), Gaps = 42/182 (23%) Query: 446 GPRGPRGDRGSQGPPGPTGN----------KGQKGEKGEPGPPGPAGERGPIGPAGPPGE 495 GP+G +G++G QGPPGP G + QKG++G PG GP G G GP GPPG Sbjct: 224 GPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG- 282 Query: 496 RGGKGSKGSQGPKGSRGSPGK------PGPQGPSGDPGPPGPPGKEGL------PGPQGP 543 G KG KG QG G RG PGK PG G GDPG PG PG++G GP GP Sbjct: 283 -GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGP 341 Query: 544 PGFQ----------GLQGTVGEPGVP---GPRGLPGLPGVPGMPGP-----KGPPGPPGP 585 PG G +G +G PG+P G RG PG+ G PG+PGP GPPGPPG Sbjct: 342 PGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGF 401 Query: 586 SG 587 G Sbjct: 402 PG 403 Score = 143 bits (361), Expect = 5e-34 Identities = 92/213 (43%), Positives = 104/213 (48%), Gaps = 59/213 (27%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGN-KGQKGEKGEPGP---------------------PG 479 QG PG RGP G G +GPPGP G KG+KGE+GEPG PG Sbjct: 260 QGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPG 319 Query: 480 PAGE---------RGPIGPAGPPG---ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPG 527 GE +G GP GPPG R G G + G KG+ G PG PG +G G PG Sbjct: 320 YPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGI--TIGEKGNIGLPGLPGEKGERGFPG 377 Query: 528 PPGPPGKEGLP-----GPQGPPGFQGLQGTVGEPG-----VPGPRGLPGLPGVPGMPGPK 577 GPPG G P GP GPPGF G +G G+ G +PGP GL G PG PG+PGP Sbjct: 378 IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPP 437 Query: 578 GP-------------PGPPGPSGAVVPLALQNE 597 GP PGPPGP G+ LQ E Sbjct: 438 GPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGE 470 Score = 143 bits (360), Expect = 7e-34 Identities = 80/156 (51%), Positives = 84/156 (53%), Gaps = 11/156 (7%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPA----GPPGER 496 L G PG GP G G GPPGP G KG +G G PG PG G +G G G PG Sbjct: 610 LPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLP 668 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G G G G G G PG+PG G G G PG PG GLPGP GP GF G+ G G P Sbjct: 669 GNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI-GLPGPPGPKGFPGIPGPPGAP 727 Query: 557 GVPGPRGLPGLPGVPGMPGPKGP-----PGPPGPSG 587 G PG GL G PG PG PGPKG PGPPGP G Sbjct: 728 GTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPG 763 Score = 142 bits (359), Expect = 9e-34 Identities = 82/196 (41%), Positives = 94/196 (47%), Gaps = 29/196 (14%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PGP GP+G+ G G PG G G KG G+ G PGP G GP GP+G PG+ G G Sbjct: 1000 GLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLP 1059 Query: 503 GSQGPKG-----SRGSPGKPGPQGPSGDPGPPGPPGKEG--------------------- 536 G +G KG S G PG PGP+G G PG PG PG +G Sbjct: 1060 GQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPG 1119 Query: 537 ---LPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLA 593 PG GPPG +G+ G G PG+PG G G G PG PGP G G PG G P Sbjct: 1120 LPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG 1179 Query: 594 LQNEPTPAPEDNGCPP 609 + EP N PP Sbjct: 1180 QKGEPGQPGFGNPGPP 1195 Score = 141 bits (356), Expect = 2e-33 Identities = 82/188 (43%), Positives = 94/188 (50%), Gaps = 20/188 (10%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 + GPPGP+G RG G G PG G G G G PGP G G G G G PG G G Sbjct: 82 IPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG 141 Query: 501 SKGSQGPKGSRGSPGKPGP------QGPSGDPGPPGPPGKEGLPGPQ------GPPGFQG 548 +G GP G G G+PG GP G+PG PGPPG +GLPGP GPPG G Sbjct: 142 LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPG 201 Query: 549 LQGTVGEPGVPGPRGLPGL--PGVPGMPGPKGPPGPPGPSGAV------VPLALQNEPTP 600 L G G PG+PGP+G GL G G G +G GPPGP G + + + Q Sbjct: 202 LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261 Query: 601 APEDNGCP 608 P D G P Sbjct: 262 LPGDRGPP 269 Score = 140 bits (353), Expect = 4e-33 Identities = 82/179 (45%), Positives = 91/179 (50%), Gaps = 34/179 (18%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQK-------GEKGEPGPPGPAGERGPIGPAGPPGE 495 GPPGP G GD+G QG G G+KG G G PG PG G GP G G PG+ Sbjct: 454 GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQ 513 Query: 496 RGGKGSKGSQGPKGSRGSPGKPGP-------------------QGPSGDPGPPGPPGKEG 536 +G KG G+ GPKG G PG PG +G G+ G PG PG G Sbjct: 514 KGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573 Query: 537 LPGPQGPPGFQGLQGTVGEPG---VPGPRGLPGLPGVPGMP---GPKGPP--GPPGPSG 587 LPG G G GL G GEPG G RG PG PG+PG+P GP GPP GPPGP G Sbjct: 574 LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVG 632 Score = 139 bits (350), Expect = 9e-33 Identities = 81/183 (44%), Positives = 97/183 (53%), Gaps = 25/183 (13%) Query: 443 GPPGPRGPRGDRGSQ----GPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP------ 492 G PG GP+GD G G PG GN G+ G+ G PG PG G+ G G G Sbjct: 644 GQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGI 703 Query: 493 -----PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG--LPGPQGP-- 543 PG G KG G GP G+ G+PG+ G +GP G PG PGP G+ G LPGP GP Sbjct: 704 PGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPG 763 Query: 544 -PGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP-----LALQNE 597 PGF+G G G+ G PGP G PG G+ G+PGPKG GP G G + P + +Q Sbjct: 764 LPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGP 823 Query: 598 PTP 600 P P Sbjct: 824 PGP 826 Score = 135 bits (341), Expect = 1e-31 Identities = 72/140 (51%), Positives = 80/140 (57%), Gaps = 15/140 (10%) Query: 463 TGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGP 522 +G KG+KGE+G PG G G G GP GPPG RG KG G GP G +G G PG G Sbjct: 41 SGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGF 100 Query: 523 SGDPGPPGPPGKEGLPGPQGPPGFQGLQGT---VGEPGVPGPRGLPGLPGVPGM------ 573 G PG PG PG +G PGPQG PG G +G G PG PG +G PG PG+PGM Sbjct: 101 PGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGS 160 Query: 574 ------PGPKGPPGPPGPSG 587 PGPKG PG PGP G Sbjct: 161 IIMSSLPGPKGNPGYPGPPG 180 Score = 134 bits (336), Expect = 4e-31 Identities = 87/206 (42%), Positives = 101/206 (49%), Gaps = 41/206 (19%) Query: 443 GPPGPRG---PR-------GDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP--IGPA 490 GPPGP G PR G++G+ G PG G KG++G G GPPG G G +GP Sbjct: 337 GPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPP 396 Query: 491 GPPGERGGKGSKGSQGPKG-----------SRGSPGKPGPQGPSG----------DPGPP 529 GPPG G +G KG +GP G G+PG PGP GP+G +PGPP Sbjct: 397 GPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPP 456 Query: 530 GPPGKEGLPGPQGPPGFQGLQGTV-------GEPGVPGPRGLPGLPGVPGMPGPKGPPGP 582 GPPG G G QG G +G +G G G PG GLPGLPG PG G G G Sbjct: 457 GPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGE 516 Query: 583 PGPSGAVVPLALQNEPTPAPEDNGCP 608 G +GA P L P AP G P Sbjct: 517 KGQAGATGPKGLPGIP-GAPGAPGFP 541 Score = 124 bits (311), Expect = 3e-28 Identities = 86/230 (37%), Positives = 98/230 (42%), Gaps = 81/230 (35%) Query: 439 TILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP------PGPAGERGPIGPAGP 492 T + GPPG G G G G G G KG+KG+ G GP PG G G G G Sbjct: 487 TGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGE 546 Query: 493 PGE-------RGGKGSKGSQGPKGSRGSPGKPGPQ------GPSGDP---------GPPG 530 PG+ +G KG GS G G G PG PG GP G+P GPPG Sbjct: 547 PGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPG 606 Query: 531 PPGKEGLP---GPQGPPGF-----------QGLQGTVGEPGVPGPR-------------- 562 PG GLP GP GPPGF QG+ G G+PG+PGP+ Sbjct: 607 NPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPG 666 Query: 563 -----------------GLPGLPGVPGMPGPKGP--------PGPPGPSG 587 GLPG PG+PG+PG KG PGPPGP G Sbjct: 667 LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKG 716 Score = 111 bits (277), Expect = 3e-24 Identities = 64/152 (42%), Positives = 75/152 (49%), Gaps = 13/152 (8%) Query: 467 GQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDP 526 GQ E P + G G GERG G +G G G G G PGP+G GD Sbjct: 21 GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80 Query: 527 GPPGPPGKEGLPGPQGPPGFQGLQGTVGEP---GVPGPRGLP---------GLPGVPGMP 574 G PGPPG +G+ GP G PGF G G G P G PGP+G+P G PG PG P Sbjct: 81 GIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP 140 Query: 575 GPKGPPGPPG-PSGAVVPLALQNEPTPAPEDN 605 G +GPPGPPG P P ++ P P+ N Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGN 172 Score = 80.1 bits (196), Expect = 7e-15 Identities = 45/106 (42%), Positives = 52/106 (49%), Gaps = 21/106 (19%) Query: 440 ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499 I++G GP G G G +G PGP GP G GP GP G PG G Sbjct: 1376 IIKGDAGPPGIPGQPGLKGLPGP---------------QGPQGLPGPTGPPGDPGRNGLP 1420 Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPG 545 G G+ G KG G PG+PG +G GPPG +GL GP GPPG Sbjct: 1421 GFDGAGGRKGDPGLPGQPGTRGLD------GPPGPDGLQGPPGPPG 1460 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 160 bits (405), Expect = 4e-39 Identities = 89/192 (46%), Positives = 101/192 (52%), Gaps = 25/192 (13%) Query: 438 FTILQGPPGP--------RGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGP 489 F +QGPPGP GP+G+ G QGPPG G +G G +G PG PG G +G G Sbjct: 1230 FPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGN 1289 Query: 490 AGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGL 549 G PG G G KG QGP G +G+PG+PG G GDPG PG PG G+ GP G PG G Sbjct: 1290 PGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGP 1349 Query: 550 QGTVGEPGVPGPRGLP-------------GLPGVPGMPGPKGPPGPPGPSGAVVPLALQN 596 +G G G PGP GLP G PG+PG PG KG PGP GP G P Sbjct: 1350 EGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTG--- 1406 Query: 597 EPTPAPEDNGCP 608 P P NG P Sbjct: 1407 -PPGDPGRNGLP 1417 Score = 157 bits (396), Expect = 4e-38 Identities = 85/173 (49%), Positives = 95/173 (54%), Gaps = 14/173 (8%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +G PG G G G GP GP G +GQKG+ G PGPPGP G RGP G G PG G G Sbjct: 50 RGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGM 109 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQG---------LQGT 552 G G G +G PG G +G G PG PG PG +G PGP G PG +G L G Sbjct: 110 PGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGP 169 Query: 553 VGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDN 605 G PG PGP G+ GLPG G+PGP GPPGPPG G P L P P+ N Sbjct: 170 KGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGL-----PGPKGN 217 Score = 155 bits (393), Expect = 1e-37 Identities = 85/184 (46%), Positives = 99/184 (53%), Gaps = 23/184 (12%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PG GP+G+ G G PG G KG G+ G PG PG G +G G G PG G G K Sbjct: 1074 GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPK 1133 Query: 503 GSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGV--PG 560 G GP G+ G PG+PGP G G PG PGPPG++G PG G PG G +G G+PG PG Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG 1193 Query: 561 PRGLPGL------------PGVPGMPGPKGPP---------GPPGPSGAVVPLALQNEPT 599 P GLPGL PG PG+PGPKG P GPPGP G+ P + Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGN 1253 Query: 600 PAPE 603 P P+ Sbjct: 1254 PGPQ 1257 Score = 154 bits (388), Expect = 4e-37 Identities = 87/177 (49%), Positives = 95/177 (53%), Gaps = 15/177 (8%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 LQG PG G G +G G PG G G KG G PG GP GE G IGP GPPG G G Sbjct: 1310 LQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSG 1369 Query: 501 S----KGSQGPKGSRGSPGK---PGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553 KG GP G G PG PGPQGP G PGP GPPG PG G PGF G G Sbjct: 1370 QSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGD---PGRNGLPGFDGAGGRK 1426 Query: 554 GEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAV--VPLALQNEPTPAPEDNGCP 608 G+PG+PG G GL G PG G +GPPGPPG S + ++ T AP+ CP Sbjct: 1427 GDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQ---CP 1480 Score = 153 bits (387), Expect = 5e-37 Identities = 87/173 (50%), Positives = 94/173 (54%), Gaps = 14/173 (8%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGS 501 +GPPGPRG +GD G GPPGP G +G G G PG PG G G G GP G G G+ Sbjct: 68 EGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGT 127 Query: 502 KGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGK---EGLPGPQG------PPGFQGLQGT 552 KG +G GS G PG GP GP G PG G PG LPGP+G PPG QGL G Sbjct: 128 KGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGP 187 Query: 553 VGEP---GVPGPRGLPGLPGVPGMPGPKGPPGP--PGPSGAVVPLALQNEPTP 600 G P G PGP GL G PG PG+PGPKG G GP G LQ P P Sbjct: 188 TGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 240 Score = 152 bits (384), Expect = 1e-36 Identities = 85/177 (48%), Positives = 94/177 (53%), Gaps = 26/177 (14%) Query: 441 LQGPPGPRGP------------RGDRGSQGPPG---PTGNKGQKGEKGEPGPPGPA---- 481 + GPPGP GP +GD G QG PG PTG KG KGE G PGPPGP Sbjct: 900 MMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNL 959 Query: 482 ----GERGPIGPAGPPGERGGKGSKGSQGPKGS---RGSPGKPGPQGPSGDPGPPGPPGK 534 GE+G G G PG G KG +G G G G PG PGP GP G+PG PG PG Sbjct: 960 LGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGL 1019 Query: 535 EGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP 591 G PG +G G G G G G PGP G+PG PG PG+PG KG G PG S +P Sbjct: 1020 IGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLP 1076 Score = 151 bits (382), Expect = 2e-36 Identities = 83/173 (47%), Positives = 96/173 (55%), Gaps = 11/173 (6%) Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGE 495 K + L G PG G G G GPPGP GN G G+PG GP G +G IG G PG Sbjct: 981 KGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGL---PGQPGLIGPPGLKGTIGDMGFPGP 1037 Query: 496 RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDP-----GPPGPPGKEGLPGPQGPPGFQGLQ 550 +G +G G G G GSPG PG +G GDP G PG PG +G PG G PG G++ Sbjct: 1038 QGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIK 1097 Query: 551 GTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP---LALQNEPTP 600 G+VG+PG+PG G PG G PG+PG G PGPPGP G P L EP P Sbjct: 1098 GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGP 1150 Score = 150 bits (380), Expect = 3e-36 Identities = 86/183 (46%), Positives = 94/183 (51%), Gaps = 27/183 (14%) Query: 443 GPPGPRGPRG--DRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIG--PAGPPGERGG 498 G PGP GP G G QGPPGP G G G+ G G PG G+ GP G GPPGERG Sbjct: 805 GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGS 864 Query: 499 KGSKGSQGPKGSRGSPGKPGPQGPSGDP---------GPPGPPGKEGLPGPQGPPGFQGL 549 G G+ GP G GSPG PG G SG P GPPGPPG G+PG G PG +G Sbjct: 865 PGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924 Query: 550 QGTVGEPGVPGPRGLPGLPGVPGMPGPKGP--------------PGPPGPSGAVVPLALQ 595 G G+PG+PGP G G G PG+PGP GP PG PG G P Q Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQ 984 Query: 596 NEP 598 P Sbjct: 985 GLP 987 Score = 150 bits (379), Expect = 4e-36 Identities = 89/197 (45%), Positives = 99/197 (50%), Gaps = 45/197 (22%) Query: 436 KNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKG-----EPGPPGPAGERGPIGPA 490 K F + GPPG G G G +GPPGP G G KGE G PGPPG G +G +GP Sbjct: 715 KGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPK 774 Query: 491 G------PPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPG--PPGPPGKEGLPGPQG 542 G PPG G G G GPKG G G+PGP GP G PG GPPG G+PGP G Sbjct: 775 GDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIG 834 Query: 543 PPGFQGLQGTVGEPG-----VPGP---RGLPGLPGVPG---------MPGP--------- 576 PG G+ G G+PG VPGP RG PG+PG PG +PG Sbjct: 835 QPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGT 894 Query: 577 ------KGPPGPPGPSG 587 GPPGPPGP G Sbjct: 895 KGEMGMMGPPGPPGPLG 911 Score = 148 bits (373), Expect = 2e-35 Identities = 92/209 (44%), Positives = 96/209 (45%), Gaps = 55/209 (26%) Query: 438 FTILQGPPGPRGPRGDRGSQGP------PGPTGNKGQKGEKGEPGPPGPAGERGPIGPAG 491 F LQGPPGP G G +G G PGP GN G G G G PGP G GPIGP G Sbjct: 139 FPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPG 198 Query: 492 PPGERGGKGSKGS-----------QGPKGSRGSPGKPGPQGPSG---------------- 524 PPG G G G QGPKG +G G GP GP G Sbjct: 199 PPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKG 258 Query: 525 ------DPGPPGPPGKEGLPGP----------QGPPGFQGLQGTVGEPGVPGPRGLPGLP 568 D GPPGPPG G PGP QG PG +G G GE G PG GLPG P Sbjct: 259 DQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDP 318 Query: 569 GVPGMPG------PKGPPGPPGPSGAVVP 591 G PG PG KG GPPGP G V+P Sbjct: 319 GYPGEPGRDGEKGQKGDTGPPGPPGLVIP 347 Score = 147 bits (370), Expect = 5e-35 Identities = 86/172 (50%), Positives = 94/172 (54%), Gaps = 12/172 (6%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQ---KGEKGEPGPPGPAGERGPIGPAGPP--GERG 497 G PG G G G G PGP G G KGE+G PG PG G G IGP GPP G G Sbjct: 570 GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG 629 Query: 498 GKGSKGSQGPKGSRGSPGKPGPQGPSG----DPGPPGPPGKEGLPGPQGPPGFQGLQGTV 553 G KG QG G+ G PG PGP+G G PG PG PG G G G PG GL G Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689 Query: 554 GEPGVPGPRGLPGLPGV--PGMPGPKGPPGPPGPSGAV-VPLALQNEPTPAP 602 G PG+PG +G PG+PG+ PG PGPKG PG PGP GA P + E P P Sbjct: 690 GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGP 741 Score = 145 bits (366), Expect = 1e-34 Identities = 90/221 (40%), Positives = 102/221 (46%), Gaps = 54/221 (24%) Query: 441 LQGPPGPR---GPRGDRGSQGP-----PGPTGNKGQKGEKGEPGPPGPAGERGP------ 486 + GPPGP G RG +G +GP PGP G GQ G G PGPPGPAG P Sbjct: 392 VMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEIC 451 Query: 487 -IGPAGPPGERGGKGSKGSQGPKGSRG-------SPGKPGPQGPSGDPGPPGPPGKEGLP 538 GP GPPG G KG +G QG KG +G G GP G G PG PGPPG G P Sbjct: 452 EPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFP 511 Query: 539 GPQ---------GPPGFQGLQGTVGEPGVPGPR----------------------GLPGL 567 G + GP G G+ G G PG PG + G PGL Sbjct: 512 GQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGL 571 Query: 568 PGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCP 608 PG+PG PG G PG PGP G + + E P P + G P Sbjct: 572 PGLPGTPGQDGLPGLPGPKGEPGGITFKGERGP-PGNPGLP 611 Score = 145 bits (365), Expect = 2e-34 Identities = 90/194 (46%), Positives = 96/194 (49%), Gaps = 27/194 (13%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 L G PG +G G G G PGP G KG G G PG PG G G GP GPPG G KG Sbjct: 691 LPGIPGSKGEPGIPGI-GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG 749 Query: 501 SKGSQ--GPKGSRGSPGKPGPQGPSGD---PGPPGPPGKEGL---------------PGP 540 G GP G G PG G GP GD PGPPGPPG+ GL PGP Sbjct: 750 EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGP 809 Query: 541 QGPPGFQGL--QGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPG--PPGPSGAVVPLALQN 596 GPPG G+ QG G PG+PGP G PGL G+PG G GPPG PGP G + Sbjct: 810 MGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPG 869 Query: 597 EPTP--APEDNGCP 608 P P P G P Sbjct: 870 APGPIGPPGSPGLP 883 Score = 144 bits (364), Expect = 2e-34 Identities = 84/182 (46%), Positives = 98/182 (53%), Gaps = 42/182 (23%) Query: 446 GPRGPRGDRGSQGPPGPTGN----------KGQKGEKGEPGPPGPAGERGPIGPAGPPGE 495 GP+G +G++G QGPPGP G + QKG++G PG GP G G GP GPPG Sbjct: 224 GPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG- 282 Query: 496 RGGKGSKGSQGPKGSRGSPGK------PGPQGPSGDPGPPGPPGKEGL------PGPQGP 543 G KG KG QG G RG PGK PG G GDPG PG PG++G GP GP Sbjct: 283 -GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGP 341 Query: 544 PGFQ----------GLQGTVGEPGVP---GPRGLPGLPGVPGMPGP-----KGPPGPPGP 585 PG G +G +G PG+P G RG PG+ G PG+PGP GPPGPPG Sbjct: 342 PGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGF 401 Query: 586 SG 587 G Sbjct: 402 PG 403 Score = 143 bits (361), Expect = 5e-34 Identities = 92/213 (43%), Positives = 104/213 (48%), Gaps = 59/213 (27%) Query: 442 QGPPGPRGPRGDRGSQGPPGPTGN-KGQKGEKGEPGP---------------------PG 479 QG PG RGP G G +GPPGP G KG+KGE+GEPG PG Sbjct: 260 QGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPG 319 Query: 480 PAGE---------RGPIGPAGPPG---ERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPG 527 GE +G GP GPPG R G G + G KG+ G PG PG +G G PG Sbjct: 320 YPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGI--TIGEKGNIGLPGLPGEKGERGFPG 377 Query: 528 PPGPPGKEGLP-----GPQGPPGFQGLQGTVGEPG-----VPGPRGLPGLPGVPGMPGPK 577 GPPG G P GP GPPGF G +G G+ G +PGP GL G PG PG+PGP Sbjct: 378 IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPP 437 Query: 578 GP-------------PGPPGPSGAVVPLALQNE 597 GP PGPPGP G+ LQ E Sbjct: 438 GPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGE 470 Score = 143 bits (360), Expect = 7e-34 Identities = 80/156 (51%), Positives = 84/156 (53%), Gaps = 11/156 (7%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPA----GPPGER 496 L G PG GP G G GPPGP G KG +G G PG PG G +G G G PG Sbjct: 610 LPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLP 668 Query: 497 GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEP 556 G G G G G G PG+PG G G G PG PG GLPGP GP GF G+ G G P Sbjct: 669 GNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI-GLPGPPGPKGFPGIPGPPGAP 727 Query: 557 GVPGPRGLPGLPGVPGMPGPKGP-----PGPPGPSG 587 G PG GL G PG PG PGPKG PGPPGP G Sbjct: 728 GTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPG 763 Score = 142 bits (359), Expect = 9e-34 Identities = 82/196 (41%), Positives = 94/196 (47%), Gaps = 29/196 (14%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502 G PGP GP+G+ G G PG G G KG G+ G PGP G GP GP+G PG+ G G Sbjct: 1000 GLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLP 1059 Query: 503 GSQGPKG-----SRGSPGKPGPQGPSGDPGPPGPPGKEG--------------------- 536 G +G KG S G PG PGP+G G PG PG PG +G Sbjct: 1060 GQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPG 1119 Query: 537 ---LPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLA 593 PG GPPG +G+ G G PG+PG G G G PG PGP G G PG G P Sbjct: 1120 LPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG 1179 Query: 594 LQNEPTPAPEDNGCPP 609 + EP N PP Sbjct: 1180 QKGEPGQPGFGNPGPP 1195 Score = 141 bits (356), Expect = 2e-33 Identities = 82/188 (43%), Positives = 94/188 (50%), Gaps = 20/188 (10%) Query: 441 LQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 + GPPGP+G RG G G PG G G G G PGP G G G G G PG G G Sbjct: 82 IPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG 141 Query: 501 SKGSQGPKGSRGSPGKPGP------QGPSGDPGPPGPPGKEGLPGPQ------GPPGFQG 548 +G GP G G G+PG GP G+PG PGPPG +GLPGP GPPG G Sbjct: 142 LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPG 201 Query: 549 LQGTVGEPGVPGPRGLPGL--PGVPGMPGPKGPPGPPGPSGAV------VPLALQNEPTP 600 L G G PG+PGP+G GL G G G +G GPPGP G + + + Q Sbjct: 202 LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261 Query: 601 APEDNGCP 608 P D G P Sbjct: 262 LPGDRGPP 269 Score = 140 bits (353), Expect = 4e-33 Identities = 82/179 (45%), Positives = 91/179 (50%), Gaps = 34/179 (18%) Query: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQK-------GEKGEPGPPGPAGERGPIGPAGPPGE 495 GPPGP G GD+G QG G G+KG G G PG PG G GP G G PG+ Sbjct: 454 GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQ 513 Query: 496 RGGKGSKGSQGPKGSRGSPGKPGP-------------------QGPSGDPGPPGPPGKEG 536 +G KG G+ GPKG G PG PG +G G+ G PG PG G Sbjct: 514 KGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573 Query: 537 LPGPQGPPGFQGLQGTVGEPG---VPGPRGLPGLPGVPGMP---GPKGPP--GPPGPSG 587 LPG G G GL G GEPG G RG PG PG+PG+P GP GPP GPPGP G Sbjct: 574 LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVG 632 Score = 139 bits (350), Expect = 9e-33 Identities = 81/183 (44%), Positives = 97/183 (53%), Gaps = 25/183 (13%) Query: 443 GPPGPRGPRGDRGSQ----GPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGP------ 492 G PG GP+GD G G PG GN G+ G+ G PG PG G+ G G G Sbjct: 644 GQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGI 703 Query: 493 -----PGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG--LPGPQGP-- 543 PG G KG G GP G+ G+PG+ G +GP G PG PGP G+ G LPGP GP Sbjct: 704 PGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPG 763 Query: 544 -PGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVP-----LALQNE 597 PGF+G G G+ G PGP G PG G+ G+PGPKG GP G G + P + +Q Sbjct: 764 LPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGP 823 Query: 598 PTP 600 P P Sbjct: 824 PGP 826 Score = 135 bits (341), Expect = 1e-31 Identities = 72/140 (51%), Positives = 80/140 (57%), Gaps = 15/140 (10%) Query: 463 TGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGP 522 +G KG+KGE+G PG G G G GP GPPG RG KG G GP G +G G PG G Sbjct: 41 SGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGF 100 Query: 523 SGDPGPPGPPGKEGLPGPQGPPGFQGLQGT---VGEPGVPGPRGLPGLPGVPGM------ 573 G PG PG PG +G PGPQG PG G +G G PG PG +G PG PG+PGM Sbjct: 101 PGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGS 160 Query: 574 ------PGPKGPPGPPGPSG 587 PGPKG PG PGP G Sbjct: 161 IIMSSLPGPKGNPGYPGPPG 180 Score = 134 bits (336), Expect = 4e-31 Identities = 87/206 (42%), Positives = 101/206 (49%), Gaps = 41/206 (19%) Query: 443 GPPGPRG---PR-------GDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGP--IGPA 490 GPPGP G PR G++G+ G PG G KG++G G GPPG G G +GP Sbjct: 337 GPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPP 396 Query: 491 GPPGERGGKGSKGSQGPKG-----------SRGSPGKPGPQGPSG----------DPGPP 529 GPPG G +G KG +GP G G+PG PGP GP+G +PGPP Sbjct: 397 GPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPP 456 Query: 530 GPPGKEGLPGPQGPPGFQGLQGTV-------GEPGVPGPRGLPGLPGVPGMPGPKGPPGP 582 GPPG G G QG G +G +G G G PG GLPGLPG PG G G G Sbjct: 457 GPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGE 516 Query: 583 PGPSGAVVPLALQNEPTPAPEDNGCP 608 G +GA P L P AP G P Sbjct: 517 KGQAGATGPKGLPGIP-GAPGAPGFP 541 Score = 124 bits (311), Expect = 3e-28 Identities = 86/230 (37%), Positives = 98/230 (42%), Gaps = 81/230 (35%) Query: 439 TILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGP------PGPAGERGPIGPAGP 492 T + GPPG G G G G G G KG+KG+ G GP PG G G G G Sbjct: 487 TGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGE 546 Query: 493 PGE-------RGGKGSKGSQGPKGSRGSPGKPGPQ------GPSGDP---------GPPG 530 PG+ +G KG GS G G G PG PG GP G+P GPPG Sbjct: 547 PGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPG 606 Query: 531 PPGKEGLP---GPQGPPGF-----------QGLQGTVGEPGVPGPR-------------- 562 PG GLP GP GPPGF QG+ G G+PG+PGP+ Sbjct: 607 NPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPG 666 Query: 563 -----------------GLPGLPGVPGMPGPKGP--------PGPPGPSG 587 GLPG PG+PG+PG KG PGPPGP G Sbjct: 667 LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKG 716 Score = 111 bits (277), Expect = 3e-24 Identities = 64/152 (42%), Positives = 75/152 (49%), Gaps = 13/152 (8%) Query: 467 GQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDP 526 GQ E P + G G GERG G +G G G G G PGP+G GD Sbjct: 21 GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80 Query: 527 GPPGPPGKEGLPGPQGPPGFQGLQGTVGEP---GVPGPRGLP---------GLPGVPGMP 574 G PGPPG +G+ GP G PGF G G G P G PGP+G+P G PG PG P Sbjct: 81 GIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP 140 Query: 575 GPKGPPGPPG-PSGAVVPLALQNEPTPAPEDN 605 G +GPPGPPG P P ++ P P+ N Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGN 172 Score = 80.1 bits (196), Expect = 7e-15 Identities = 45/106 (42%), Positives = 52/106 (49%), Gaps = 21/106 (19%) Query: 440 ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499 I++G GP G G G +G PGP GP G GP GP G PG G Sbjct: 1373 IIKGDAGPPGIPGQPGLKGLPGP---------------QGPQGLPGPTGPPGDPGRNGLP 1417 Query: 500 GSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPG 545 G G+ G KG G PG+PG +G GPPG +GL GP GPPG Sbjct: 1418 GFDGAGGRKGDPGLPGQPGTRGLD------GPPGPDGLQGPPGPPG 1457 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.133 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 36,810,230 Number of Sequences: 37866 Number of extensions: 2721550 Number of successful extensions: 83165 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 689 Number of HSP's successfully gapped in prelim test: 1857 Number of HSP's that attempted gapping in prelim test: 15043 Number of HSP's gapped (non-prelim): 17970 length of query: 742 length of database: 18,247,518 effective HSP length: 110 effective length of query: 632 effective length of database: 14,082,258 effective search space: 8899987056 effective search space used: 8899987056 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.