Search of human proteins with 183583553

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]
         (2526 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]             5082   0.0  
gi|156616290 collagen type VI alpha 6 [Homo sapiens]                 2277   0.0  
gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s...  1032   0.0  
gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s...  1032   0.0  
gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo ...   993   0.0  
gi|240255540 alpha 3 type VI collagen isoform 3 precursor [Homo ...   393   e-108
gi|240255542 alpha 3 type VI collagen isoform 2 precursor [Homo ...   332   3e-90
gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Hom...   310   2e-83
gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]      305   3e-82
gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [H...   302   3e-81
gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Ho...   302   3e-81
gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]       281   6e-75
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   277   8e-74
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]   275   3e-73
gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo s...   274   7e-73
gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo s...   274   7e-73
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]              274   9e-73
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   273   1e-72
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   273   1e-72
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   273   1e-72
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   271   5e-72
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      271   8e-72
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...   271   8e-72
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...   271   8e-72
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...   271   8e-72
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   269   2e-71
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   269   2e-71
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   268   4e-71
gi|11386161 alpha 2 type IX collagen [Homo sapiens]                   267   1e-70
gi|154759255 collagen, type XXVIII precursor [Homo sapiens]           266   2e-70

>gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]
          Length = 2526

 Score = 5082 bits (13183), Expect = 0.0
 Identities = 2526/2526 (100%), Positives = 2526/2526 (100%)

Query: 1    MKILLIIFVLIIWTETLADQSPGPGPVYADVVFLVDSSDHLGPKSFPFVKTFINKMINSL 60
            MKILLIIFVLIIWTETLADQSPGPGPVYADVVFLVDSSDHLGPKSFPFVKTFINKMINSL
Sbjct: 1    MKILLIIFVLIIWTETLADQSPGPGPVYADVVFLVDSSDHLGPKSFPFVKTFINKMINSL 60

Query: 61   PIEANKYRVALAQYSDEFHSEFHLSTFKGRSPMLNHLKKNFQFIGGSLQIGKALQEAHRT 120
            PIEANKYRVALAQYSDEFHSEFHLSTFKGRSPMLNHLKKNFQFIGGSLQIGKALQEAHRT
Sbjct: 61   PIEANKYRVALAQYSDEFHSEFHLSTFKGRSPMLNHLKKNFQFIGGSLQIGKALQEAHRT 120

Query: 121  YFSAPINGRDRKQFPPILVVLASAESEDEVEEASKALQKDGVKIISVGVQKASEENLKAM 180
            YFSAPINGRDRKQFPPILVVLASAESEDEVEEASKALQKDGVKIISVGVQKASEENLKAM
Sbjct: 121  YFSAPINGRDRKQFPPILVVLASAESEDEVEEASKALQKDGVKIISVGVQKASEENLKAM 180

Query: 181  ATSHFHFNLRTIRDLSTFSQNMTQIIKDVTKYKEGAVDADMQVHFPISCQKDSLADLVFL 240
            ATSHFHFNLRTIRDLSTFSQNMTQIIKDVTKYKEGAVDADMQVHFPISCQKDSLADLVFL
Sbjct: 181  ATSHFHFNLRTIRDLSTFSQNMTQIIKDVTKYKEGAVDADMQVHFPISCQKDSLADLVFL 240

Query: 241  VDESLGTGGNLRHLQTFLENITSSMDVKENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQ 300
            VDESLGTGGNLRHLQTFLENITSSMDVKENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQ
Sbjct: 241  VDESLGTGGNLRHLQTFLENITSSMDVKENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQ 300

Query: 301  QIKNLSIQVGKSNTGAAIDQMRRDGFSESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALN 360
            QIKNLSIQVGKSNTGAAIDQMRRDGFSESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALN
Sbjct: 301  QIKNLSIQVGKSNTGAAIDQMRRDGFSESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALN 360

Query: 361  LRLEDVNVFALSIQGANNTQLEEIVSYPPEQTISTLKSYADLETYSTKFLKKLQNEIWSQ 420
            LRLEDVNVFALSIQGANNTQLEEIVSYPPEQTISTLKSYADLETYSTKFLKKLQNEIWSQ
Sbjct: 361  LRLEDVNVFALSIQGANNTQLEEIVSYPPEQTISTLKSYADLETYSTKFLKKLQNEIWSQ 420

Query: 421  ISTYAEQRNLDKTGCVDTKEADIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVR 480
            ISTYAEQRNLDKTGCVDTKEADIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVR
Sbjct: 421  ISTYAEQRNLDKTGCVDTKEADIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVR 480

Query: 481  VGVVQYSDDTEVEFYITDYSNDIDLRKAIFNIKQLTGGTYTGKALDYILQIIKNGMKDRM 540
            VGVVQYSDDTEVEFYITDYSNDIDLRKAIFNIKQLTGGTYTGKALDYILQIIKNGMKDRM
Sbjct: 481  VGVVQYSDDTEVEFYITDYSNDIDLRKAIFNIKQLTGGTYTGKALDYILQIIKNGMKDRM 540

Query: 541  SKVPCYLIVLTDGMSTDRVVEPAKRLRAEQITVHAVGIGAANKIELQEIAGKEERVSFGQ 600
            SKVPCYLIVLTDGMSTDRVVEPAKRLRAEQITVHAVGIGAANKIELQEIAGKEERVSFGQ
Sbjct: 541  SKVPCYLIVLTDGMSTDRVVEPAKRLRAEQITVHAVGIGAANKIELQEIAGKEERVSFGQ 600

Query: 601  NFDALKSIKNEVVREICAEKGCEDMKADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQI 660
            NFDALKSIKNEVVREICAEKGCEDMKADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQI
Sbjct: 601  NFDALKSIKNEVVREICAEKGCEDMKADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQI 660

Query: 661  GADKTQIGVVQFSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTLTGKALNFVGQYFTH 720
            GADKTQIGVVQFSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTLTGKALNFVGQYFTH
Sbjct: 661  GADKTQIGVVQFSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTLTGKALNFVGQYFTH 720

Query: 721  SKGARLGAKKFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGDSSL 780
            SKGARLGAKKFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGDSSL
Sbjct: 721  SKGARLGAKKFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGDSSL 780

Query: 781  VFHVENFDHLKALERKLIFRVCALHDCKRITLLDVVFVLDHSGSIKKQYQDHMINLTIHL 840
            VFHVENFDHLKALERKLIFRVCALHDCKRITLLDVVFVLDHSGSIKKQYQDHMINLTIHL
Sbjct: 781  VFHVENFDHLKALERKLIFRVCALHDCKRITLLDVVFVLDHSGSIKKQYQDHMINLTIHL 840

Query: 841  VKKADVGRDRVQFGALKYSDQPNILFYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKHA 900
            VKKADVGRDRVQFGALKYSDQPNILFYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKHA
Sbjct: 841  VKKADVGRDRVQFGALKYSDQPNILFYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKHA 900

Query: 901  NALFTEEHGSRIKQNVKQMLIVITDGESHDHDQLNDTALELRNKGITIFAVGVGKANQKE 960
            NALFTEEHGSRIKQNVKQMLIVITDGESHDHDQLNDTALELRNKGITIFAVGVGKANQKE
Sbjct: 901  NALFTEEHGSRIKQNVKQMLIVITDGESHDHDQLNDTALELRNKGITIFAVGVGKANQKE 960

Query: 961  LEGMAGNKNNTIYVDNFDKLKDVFTLVQERMCTEAPEVCHLQEADVIFLCDGSDRVSNSD 1020
            LEGMAGNKNNTIYVDNFDKLKDVFTLVQERMCTEAPEVCHLQEADVIFLCDGSDRVSNSD
Sbjct: 961  LEGMAGNKNNTIYVDNFDKLKDVFTLVQERMCTEAPEVCHLQEADVIFLCDGSDRVSNSD 1020

Query: 1021 FVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSNYQSIIELKNSLTKTQWKTQIQNVSKSGG 1080
            FVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSNYQSIIELKNSLTKTQWKTQIQNVSKSGG
Sbjct: 1021 FVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSNYQSIIELKNSLTKTQWKTQIQNVSKSGG 1080

Query: 1081 FPRIDFALKKVSNMFNLHAGGRRNAGVPQTLVVITSGDPRYDVADAVKTLKDLGICVLVL 1140
            FPRIDFALKKVSNMFNLHAGGRRNAGVPQTLVVITSGDPRYDVADAVKTLKDLGICVLVL
Sbjct: 1081 FPRIDFALKKVSNMFNLHAGGRRNAGVPQTLVVITSGDPRYDVADAVKTLKDLGICVLVL 1140

Query: 1141 GIGDVYKEHLLPITGNSEKIITFQDFDKLKNVDVKKRIIREICQSCGKTNCFMDIVVGFD 1200
            GIGDVYKEHLLPITGNSEKIITFQDFDKLKNVDVKKRIIREICQSCGKTNCFMDIVVGFD
Sbjct: 1141 GIGDVYKEHLLPITGNSEKIITFQDFDKLKNVDVKKRIIREICQSCGKTNCFMDIVVGFD 1200

Query: 1201 ISTHVQGQPLFQGHPQLESYLPGILEDISSIKGVSCGAGTEAQVSLAFKVNSDQGFPAKF 1260
            ISTHVQGQPLFQGHPQLESYLPGILEDISSIKGVSCGAGTEAQVSLAFKVNSDQGFPAKF
Sbjct: 1201 ISTHVQGQPLFQGHPQLESYLPGILEDISSIKGVSCGAGTEAQVSLAFKVNSDQGFPAKF 1260

Query: 1261 QIYQKAVFDSLLQVNVSGPTHLNAQFLRSLWDTFKDKSASRGQVLLIFSDGLQSESNIML 1320
            QIYQKAVFDSLLQVNVSGPTHLNAQFLRSLWDTFKDKSASRGQVLLIFSDGLQSESNIML
Sbjct: 1261 QIYQKAVFDSLLQVNVSGPTHLNAQFLRSLWDTFKDKSASRGQVLLIFSDGLQSESNIML 1320

Query: 1321 ENQSDRLREAGLDALLVVSLNTTAHHEFSSFEFGKRFDYRTHLTIGMRELGKKLSQYLGN 1380
            ENQSDRLREAGLDALLVVSLNTTAHHEFSSFEFGKRFDYRTHLTIGMRELGKKLSQYLGN
Sbjct: 1321 ENQSDRLREAGLDALLVVSLNTTAHHEFSSFEFGKRFDYRTHLTIGMRELGKKLSQYLGN 1380

Query: 1381 IAERTCCCTFCKCPGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKG 1440
            IAERTCCCTFCKCPGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKG
Sbjct: 1381 IAERTCCCTFCKCPGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKG 1440

Query: 1441 IAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRG 1500
            IAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRG
Sbjct: 1441 IAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRG 1500

Query: 1501 APGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQR 1560
            APGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQR
Sbjct: 1501 APGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQR 1560

Query: 1561 GLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGST 1620
            GLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGST
Sbjct: 1561 GLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGST 1620

Query: 1621 GRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKG 1680
            GRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKG
Sbjct: 1621 GRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKG 1680

Query: 1681 DIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCDLIRF 1740
            DIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCDLIRF
Sbjct: 1681 DIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCDLIRF 1740

Query: 1741 LREHSPCWKEKCPAYPTELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGAR 1800
            LREHSPCWKEKCPAYPTELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGAR
Sbjct: 1741 LREHSPCWKEKCPAYPTELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGAR 1800

Query: 1801 VAMVSYNSGTSYLIRWSDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYA 1860
            VAMVSYNSGTSYLIRWSDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYA
Sbjct: 1801 VAMVSYNSGTSYLIRWSDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYA 1860

Query: 1861 GANVRRVAVFFSNGQTASRSSIITATMEFSALDISPTVFAFDERVFLEAFGFDNTGTFQV 1920
            GANVRRVAVFFSNGQTASRSSIITATMEFSALDISPTVFAFDERVFLEAFGFDNTGTFQV
Sbjct: 1861 GANVRRVAVFFSNGQTASRSSIITATMEFSALDISPTVFAFDERVFLEAFGFDNTGTFQV 1920

Query: 1921 IPVPPNGENQTLERLRRCALCYDKCFPNACIREAFLPEDSYMDVVFLIDNSRNIAKDEFK 1980
            IPVPPNGENQTLERLRRCALCYDKCFPNACIREAFLPEDSYMDVVFLIDNSRNIAKDEFK
Sbjct: 1921 IPVPPNGENQTLERLRRCALCYDKCFPNACIREAFLPEDSYMDVVFLIDNSRNIAKDEFK 1980

Query: 1981 AVKALVSSVIDNFNIASDPLISDSGDRIALLSYSPWESSRRKMGTVKTEFDFITYDNQLL 2040
            AVKALVSSVIDNFNIASDPLISDSGDRIALLSYSPWESSRRKMGTVKTEFDFITYDNQLL
Sbjct: 1981 AVKALVSSVIDNFNIASDPLISDSGDRIALLSYSPWESSRRKMGTVKTEFDFITYDNQLL 2040

Query: 2041 MKNHIQTSFQQLNGEATIGRALLWTTENLFPETPYLRKHKVIFVVSAGENYERKEFVKMM 2100
            MKNHIQTSFQQLNGEATIGRALLWTTENLFPETPYLRKHKVIFVVSAGENYERKEFVKMM
Sbjct: 2041 MKNHIQTSFQQLNGEATIGRALLWTTENLFPETPYLRKHKVIFVVSAGENYERKEFVKMM 2100

Query: 2101 ALRAKCQGYVIFVISLGSTRKDDMEELASYPLDQHLIQLGRIHKPDLNYIAKFLKPFLYS 2160
            ALRAKCQGYVIFVISLGSTRKDDMEELASYPLDQHLIQLGRIHKPDLNYIAKFLKPFLYS
Sbjct: 2101 ALRAKCQGYVIFVISLGSTRKDDMEELASYPLDQHLIQLGRIHKPDLNYIAKFLKPFLYS 2160

Query: 2161 VRRGFNQYPPPMLEDACRLINLGGENIQNDGFQFVTELQEDFLGGNGFIGQELNSGRESP 2220
            VRRGFNQYPPPMLEDACRLINLGGENIQNDGFQFVTELQEDFLGGNGFIGQELNSGRESP
Sbjct: 2161 VRRGFNQYPPPMLEDACRLINLGGENIQNDGFQFVTELQEDFLGGNGFIGQELNSGRESP 2220

Query: 2221 FVKTEDNGSDYLVYLPSQMFEPQKLMINYEKDQKSAEIASLTSGHENYGRKEEPDHTYEP 2280
            FVKTEDNGSDYLVYLPSQMFEPQKLMINYEKDQKSAEIASLTSGHENYGRKEEPDHTYEP
Sbjct: 2221 FVKTEDNGSDYLVYLPSQMFEPQKLMINYEKDQKSAEIASLTSGHENYGRKEEPDHTYEP 2280

Query: 2281 GDVSLQEYYMDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLS 2340
            GDVSLQEYYMDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLS
Sbjct: 2281 GDVSLQEYYMDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLS 2340

Query: 2341 YSPPGYMPNTEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVG 2400
            YSPPGYMPNTEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVG
Sbjct: 2341 YSPPGYMPNTEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVG 2400

Query: 2401 TPNLRKNKVIFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHNDKELEELASH 2460
            TPNLRKNKVIFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHNDKELEELASH
Sbjct: 2401 TPNLRKNKVIFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHNDKELEELASH 2460

Query: 2461 PLDHHLVQLGRTHKPDWNYIIKFVKPFVHLIRRAINKYPTEDMKATCVNMTSPNPENGGT 2520
            PLDHHLVQLGRTHKPDWNYIIKFVKPFVHLIRRAINKYPTEDMKATCVNMTSPNPENGGT
Sbjct: 2461 PLDHHLVQLGRTHKPDWNYIIKFVKPFVHLIRRAINKYPTEDMKATCVNMTSPNPENGGT 2520

Query: 2521 ENTVLW 2526
            ENTVLW
Sbjct: 2521 ENTVLW 2526


>gi|156616290 collagen type VI alpha 6 [Homo sapiens]
          Length = 2263

 Score = 2277 bits (5900), Expect = 0.0
 Identities = 1188/2194 (54%), Positives = 1559/2194 (71%), Gaps = 24/2194 (1%)

Query: 3    ILLIIFVLIIWTETLADQSPGPGPVYADVVFLVDSSDHLGPKSFPFVKTFINKMINSLPI 62
            +LLI+F++II +    +Q  GP   YADVVFLVDSSD LG KSFPFVK FI KMI+SLPI
Sbjct: 2    MLLILFLVIICSHISVNQDSGPE--YADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPI 59

Query: 63   EANKYRVALAQYSDEFHSEFHLSTFKGRSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYF 122
            EA+KYRVALAQYSD+ HSEFHLSTFKGRSPMLNHL+KNF FIGGSLQIGKALQEAHRTYF
Sbjct: 60   EADKYRVALAQYSDKLHSEFHLSTFKGRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYF 119

Query: 123  SAPINGRDRKQFPPILVVLASAESEDEVEEASKALQKDGVKIISVGVQKASEENLKAMAT 182
            SAP NGRD+KQFPPILVVLAS+ESED VEEASKAL+KDGVKIISVGVQKASEENLKAMAT
Sbjct: 120  SAPANGRDKKQFPPILVVLASSESEDNVEEASKALRKDGVKIISVGVQKASEENLKAMAT 179

Query: 183  SHFHFNLRTIRDLSTFSQNMTQIIKDVTKYKEGAVDADMQVHFPISCQKDSLADLVFLVD 242
            S FHFNLRT+RDLS FSQNMT IIKDV KYKEGAVD D+ V    +CQ  S+AD+VFL+D
Sbjct: 180  SQFHFNLRTVRDLSMFSQNMTHIIKDVIKYKEGAVD-DIFVE---ACQGPSMADVVFLLD 235

Query: 243  ESL-GTGGNLRHLQTFLENITSSMDVKENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQ 301
             S+ G+  N  +L+ FLE   S++D+KENCMR+GL++YSN  K I+ L     +SE  Q 
Sbjct: 236  MSINGSEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGINKSEVLQH 295

Query: 302  IKNLSIQVGKSNTGAAIDQMRRDGFSESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNL 361
            I+NLS + GK+ TGAAI ++R++ FS   GSR+ QGVPQIAVLVTHR S+D V  AA+NL
Sbjct: 296  IQNLSPRTGKAYTGAAIKKLRKEVFSARNGSRKNQGVPQIAVLVTHRDSEDNVTKAAVNL 355

Query: 362  RLEDVNVFALSIQGANNTQLEEIVSYPPEQTISTLKSYADLETYSTKFLKKLQNEIWSQI 421
            R E V +F L I+GA++TQLE+I S+P EQ +S LK++ADL  ++  FLKKL+N+I   +
Sbjct: 356  RREGVTIFTLGIEGASDTQLEKIASHPAEQYVSKLKTFADLAAHNQTFLKKLRNQITHTV 415

Query: 422  STYAEQRNLDKTGCVDTKEADIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRV 481
            S ++E+    K+GCVDT+EADI+ LIDGS S Q   F ++K F+ EV  MF+I P KVRV
Sbjct: 416  SVFSERTETLKSGCVDTEEADIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRV 475

Query: 482  GVVQYSDDTEVEFYITDYSNDIDLRKAIFNIKQLTGGTYTGKALDYILQIIKNGMKDRMS 541
            G VQY+D  ++EF I  YSN  DL KAI NI+Q+ G T TG AL++ L +++   K R +
Sbjct: 476  GAVQYADSWDLEFEINKYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSLLQKAKKQRGN 535

Query: 542  KVPCYLIVLTDGMSTDRVVEPAKRLRAEQITVHAVGIGAANKIELQEIAGKEERVSFGQN 601
            KVPC+L+VLT+GMS D ++EPA RLR E I V+A+GI  AN+ +L+EIAG+E+RV +  +
Sbjct: 536  KVPCHLVVLTNGMSKDSILEPANRLREEHIRVYAIGIKEANQTQLREIAGEEKRVYYVHD 595

Query: 602  FDALKSIKNEVVREICAEKGCEDMKADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIG 661
            FDALK I+N+VV+EIC E+ C++MKADIMFLVDSS SIG ENF KMK FMKNL++K QIG
Sbjct: 596  FDALKDIRNQVVQEICTEEACKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIG 655

Query: 662  ADKTQIGVVQFSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTLTGKALNFVGQYFTHS 721
             D+ QIGVVQFSD  KEEFQLNR+ +Q +IS+AID+M+ I + TLTG AL+FV QYF+ +
Sbjct: 656  PDRVQIGVVQFSDINKEEFQLNRFMSQSDISNAIDQMAHIGQTTLTGSALSFVSQYFSPT 715

Query: 722  KGARLGAKKFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGDSSLV 781
            KGAR   +KFLILITDG AQD V++PA +LR + V I+SVGV+ +N +QLEEISG   +V
Sbjct: 716  KGARPNIRKFLILITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMV 775

Query: 782  FHVENFDHLKALERKLIFRVCA-LHDCKRITLLDVVFVLDHSGSIKKQYQDHMINLTIHL 840
            F+VENFD L+ +E  L+F +C+   +CKRI +LDVVFV+D SGSI     + M +  I L
Sbjct: 776  FYVENFDILQRIEDDLVFGICSPREECKRIEVLDVVFVIDSSGSIDYDEYNIMKDFMIGL 835

Query: 841  VKKADVGRDRVQFGALKYSDQPNILFYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKHA 900
            VKKADVG+++V+FGALKY+D P +LFYL+ +  +  +I  L+  +  GG+TYTA+AL  +
Sbjct: 836  VKKADVGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGSTYTAEALGFS 895

Query: 901  NALFTEEHGSRIKQNVKQMLIVITDGESHDHDQLNDTALELRNKGITIFAVGVGKANQKE 960
            + +FTE  GSR+ + V Q+LIVITDGESHD D+LN TA  LR+KGI + AVG+  AN  E
Sbjct: 896  DHMFTEARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVE 955

Query: 961  LEGMAGNKNNTIYVDNFDKLKDVFTLVQERMCTEAPEVCHLQEADVIFLCDGSDRVSNSD 1020
            L  MAG+ +   +V+ F  LK +F+ V   +C  +   C + + D++FL DGS  +  +D
Sbjct: 956  LLAMAGSSDKYFFVETFGGLKGIFSDVTASVCNSSKVDCEIDKVDLVFLMDGSTSIQPND 1015

Query: 1021 FVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSNYQSIIELKNSLTKTQWKTQIQNVSKSGG 1080
            F  M  FL+ ++ +FD+   R++IG AQF   Y     L   + + +   QI+N+ +  G
Sbjct: 1016 FKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIGEKEISFQIENIKQIFG 1075

Query: 1081 FPRIDFALKKVSNMFNLHAGGRRNAGVPQTLVVITSGDPRYDVADAVKTLKDLGICVLVL 1140
               I  AL++V + F    G R N G PQ L+V+T G  + +VA A + L+  GI +  +
Sbjct: 1076 NTHIGAALREVEHYFRPDMGSRINTGTPQVLLVLTDGQSQDEVAQAAEALRHRGIDIYSV 1135

Query: 1141 GIGDVYKEHLLPITGNSEKIITFQDFDKLKNVDVKKRIIREICQSCGKTNCFMDIVVGFD 1200
            GIGDV  + L+ ITG +EK +T  +FD+LK V+  KRI+R IC + G++NCF+D+VVGFD
Sbjct: 1136 GIGDVDDQQLIQITGTAEKKLTVHNFDELKKVN--KRIVRNICTTAGESNCFVDVVVGFD 1193

Query: 1201 ISTHVQGQPLFQGHPQLESYLPGILEDISSIKGVSCGAGTEAQVSLAFKV-NSDQGFPAK 1259
            +ST  +GQ L +G P +E+YL  IL  ISS+ GVSC  GTE QVS+AF+V N+ + +  K
Sbjct: 1194 VSTQEKGQTLLEGQPWMETYLQDILRAISSLNGVSCEVGTETQVSVAFQVTNAMEKYSPK 1253

Query: 1260 FQIYQKAVFDSLLQVNVSGPTHLNAQFLRSLWDTFKDKSASRGQVLLIFSDGLQSESNIM 1319
            F+IY + + +SL  + V GP+ LNA  L SLWDTF++KSA+RG+V+L+FSDGL  +    
Sbjct: 1254 FEIYSENILNSLKDITVKGPSLLNANLLDSLWDTFQNKSAARGKVVLLFSDGLDDDVE-K 1312

Query: 1320 LENQSDRLREAGLDALLVVSLNTTAHH----EFSSFEFGKRFDYRTHLTIGMRELGKKLS 1375
            LE +SD LR+ GL+AL+ V+L+  A      +    EFGK F+YRT L+IGMRELG +LS
Sbjct: 1313 LEQKSDELRKEGLNALITVALDGPADSSDLADLPYIEFGKGFEYRTQLSIGMRELGSRLS 1372

Query: 1376 QYLGNIAERTCCCTFCKCPGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGP 1435
            + L N+AERTCCC FCKC G  G  G  G    +G  G KGS G+ GE+G  G RG  GP
Sbjct: 1373 KQLVNVAERTCCCLFCKCIGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGP 1432

Query: 1436 QGDKGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGS 1495
             G++G  GC G  G KG +G +G +G  G++GIDGL+GE+G +G PG KGEKGD GSQGS
Sbjct: 1433 VGEQGTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGS 1492

Query: 1496 PGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRG 1555
            PG RG PG  G KG  GDPG PG +++I+G  G KGE+GRQGR G  G  G+P SR    
Sbjct: 1493 PGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTA 1552

Query: 1556 REGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMG 1615
              G+RG  G  G  G PGP G  G+ GL+GPQG +G  G KGEKG  G KGPQG PG  G
Sbjct: 1553 AHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGG 1612

Query: 1616 AKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGD 1675
              G+ GR G  G KGEPG  G+ G VG  G RG QG+ G PGYG +GRKG KG  GFPG+
Sbjct: 1613 EAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGE 1672

Query: 1676 AGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQC 1735
            +G KG+IG+PG PG  G KG RG  ++ GL GE GS G PGPPG++G+KG  G   +S C
Sbjct: 1673 SGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTC 1732

Query: 1736 DLIRFLREHSP--CWKEKCPAYPTELVFALDNSYDVTEESFNKTRDIITSIVNDLNIREN 1793
            +LI+++R+ SP    K +CP +PTELVFALD+S DVTE+ F + ++++  +V D+ +REN
Sbjct: 1733 ELIQYVRDRSPGRHGKPECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVREN 1792

Query: 1794 NCPVGARVAMVSYNSGTSYLIRWSDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRN 1853
            +CPVGA +A++SYNS   +L+R+SD  +K QLL+++  I Y+ ++  R++G AMRF++RN
Sbjct: 1793 SCPVGAHIAILSYNSHARHLVRFSDAYKKSQLLREIETIPYERSSASREIGRAMRFISRN 1852

Query: 1854 VFKRTYAGANVRRVAVFFSNGQTASRSSIITATMEFSALDISPTVFAFDERVFL-EAFGF 1912
            VFKRT  GA+ R++A FFS+GQ+A   SI TA MEF AL+I P V  F     +  AF  
Sbjct: 1853 VFKRTLPGAHTRKIATFFSSGQSADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAI 1912

Query: 1913 DNTGTFQVIPVPPNGEN-QTLERLRRCALCYDKCFPNA-CIREAFLPEDSYMDVVFLIDN 1970
            D+TGTFQVI VP   +    LERL+RC  CYD C P+A C +    P  SYMD  FL+D 
Sbjct: 1913 DDTGTFQVIVVPSGADYIPALERLQRCTFCYDVCKPDASCDQARPPPVQSYMDAAFLLDA 1972

Query: 1971 SRNIAKDEFKAVKALVSSVIDNFNIASDPLISDSGDRIALLSYSPWE-SSRRKMGTVKTE 2029
            SRN+   EF+ ++A + +++D+F I  +P  S +GDR+ALLS++P +     +   V+ E
Sbjct: 1973 SRNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAE 2032

Query: 2030 FDFITYDNQLLMKNHIQTSFQQLNGEATIGRALLWTTENLFPETPYLRKHKVIFVVSAGE 2089
            F+  TY ++ LMK H+  S +QLNG+A IG AL WT +N+F  TP LR++KVIFV+SAGE
Sbjct: 2033 FNLTTYRSKRLMKRHVHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRNKVIFVISAGE 2092

Query: 2090 -NYERKEFVKMMALRAKCQGYVIFVISLGSTRKD-DMEELASYPLDQHLIQLGRIHKPDL 2147
             ++   E +K  +LRAKCQGY +FV SLG    D ++E+LAS+PLD HL+QLGRIHKPD 
Sbjct: 2093 TSHLDGEILKKESLRAKCQGYALFVFSLGPIWDDKELEDLASHPLDHHLVQLGRIHKPDH 2152

Query: 2148 NYIAKFLKPFLYSVRRGFNQYPPPMLEDACRLIN 2181
            +Y  KF+K F+ S+RR  N+YPP  L+  C  +N
Sbjct: 2153 SYGVKFVKSFINSIRRAINKYPPINLKIKCNRLN 2186



 Score =  303 bits (776), Expect = 1e-81
 Identities = 145/245 (59%), Positives = 191/245 (77%), Gaps = 1/245 (0%)

Query: 2273 EPDHTYEPGDVSLQEYYMDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTL 2332
            +PD + +       + YMD AFL+DAS+ +GS EF++++AF+ ++LD+F I P P TS  
Sbjct: 1947 KPDASCDQARPPPVQSYMDAAFLLDASRNMGSAEFEDIRAFLGALLDHFEITPEPETSVT 2006

Query: 2333 GDRVAVLSYSPPGYMPNTEECPVYLEFDLVTYNSIHQMKHHLQDS-QQLNGDVFIGHALQ 2391
            GDRVA+LS++PP ++PNT++ PV  EF+L TY S   MK H+ +S +QLNGD FIGHALQ
Sbjct: 2007 GDRVALLSHAPPDFLPNTQKSPVRAEFNLTTYRSKRLMKRHVHESVKQLNGDAFIGHALQ 2066

Query: 2392 WTIDNVFVGTPNLRKNKVIFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHND 2451
            WT+DNVF+ TPNLR+NKVIFVISAGET+ LD ++L+  SLRAKCQGY++FVFS GP  +D
Sbjct: 2067 WTLDNVFLSTPNLRRNKVIFVISAGETSHLDGEILKKESLRAKCQGYALFVFSLGPIWDD 2126

Query: 2452 KELEELASHPLDHHLVQLGRTHKPDWNYIIKFVKPFVHLIRRAINKYPTEDMKATCVNMT 2511
            KELE+LASHPLDHHLVQLGR HKPD +Y +KFVK F++ IRRAINKYP  ++K  C  + 
Sbjct: 2127 KELEDLASHPLDHHLVQLGRIHKPDHSYGVKFVKSFINSIRRAINKYPPINLKIKCNRLN 2186

Query: 2512 SPNPE 2516
            S +P+
Sbjct: 2187 SIDPK 2191



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 48/221 (21%), Positives = 97/221 (43%), Gaps = 20/221 (9%)

Query: 2291 DVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPNT 2350
            DV FL+D S     + F  +K F+   +    I    +      RV +++YS    + N+
Sbjct: 229  DVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCM------RVGLVAYSNETKVINS 282

Query: 2351 EECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLRKNKVI 2410
                +          +  ++  H+Q+     G  + G A++     VF      RKN+ +
Sbjct: 283  LSMGI----------NKSEVLQHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSRKNQGV 332

Query: 2411 FVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHNDKELEELASHPLDHHLVQLG 2470
              I+   T+   +D +   ++  + +G +IF        +D +LE++ASHP + ++ +L 
Sbjct: 333  PQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGI-EGASDTQLEKIASHPAEQYVSKL- 390

Query: 2471 RTHKPDWNYIIKFVKPFVHLIRRAINKYP--TEDMKATCVN 2509
            +T      +   F+K   + I   ++ +   TE +K+ CV+
Sbjct: 391  KTFADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSGCVD 431



 Score = 48.9 bits (115), Expect = 6e-05
 Identities = 49/179 (27%), Positives = 74/179 (41%), Gaps = 18/179 (10%)

Query: 2289 YMDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMP 2348
            Y DV FL+D+S R+GS  F  VK FIT ++    I           RVA+  YS      
Sbjct: 25   YADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKY------RVALAQYSD----- 73

Query: 2349 NTEECPVYLEFDLVTYNSIHQMKHHLQDS-QQLNGDVFIGHALQWTIDNVFVGTPNLRKN 2407
                  ++ EF L T+     M +HL+ +   + G + IG ALQ      F    N R  
Sbjct: 74   -----KLHSEFHLSTFKGRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDK 128

Query: 2408 KVIFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHNDKELEELASHPLDHHL 2466
            K    I     +S  +D +   S   +  G  I       K +++ L+ +A+     +L
Sbjct: 129  KQFPPILVVLASSESEDNVEEASKALRKDGVKIISVGV-QKASEENLKAMATSQFHFNL 186



 Score = 48.5 bits (114), Expect = 8e-05
 Identities = 50/190 (26%), Positives = 89/190 (46%), Gaps = 29/190 (15%)

Query: 2273 EPDHTYEPGDVSLQEYYMDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTL 2332
            E   T + G V  +E   D+  LID S    + +F E+K F++ V+  F+IAP  +    
Sbjct: 420  ERTETLKSGCVDTEE--ADIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKV---- 473

Query: 2333 GDRVAVLSYSPPGYMPNTEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQW 2392
              RV  + Y+              LEF++  Y++   +   +++ +Q+ G+   G AL +
Sbjct: 474  --RVGAVQYADSW----------DLEFEINKYSNKQDLGKAIENIRQMGGNTNTGAALNF 521

Query: 2393 TIDNVFVGTPNLRKNKV---IFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKH 2449
            T+ ++       R NKV   + V+    TN + KD +   + R + +   I V++ G K 
Sbjct: 522  TL-SLLQKAKKQRGNKVPCHLVVL----TNGMSKDSILEPANRLREE--HIRVYAIGIKE 574

Query: 2450 -NDKELEELA 2458
             N  +L E+A
Sbjct: 575  ANQTQLREIA 584



 Score = 42.4 bits (98), Expect = 0.006
 Identities = 42/181 (23%), Positives = 81/181 (44%), Gaps = 30/181 (16%)

Query: 2286 QEYYMDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPG 2345
            +E   D+ FL+D+S  +G + F ++K F+ +++    I P  +      ++ V+ +S   
Sbjct: 617  KEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRV------QIGVVQFSD-- 668

Query: 2346 YMPNTEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLR 2405
               N E      EF L  + S   + + +     +      G AL + +   F  T   R
Sbjct: 669  --INKE------EFQLNRFMSQSDISNAIDQMAHIGQTTLTGSALSF-VSQYFSPTKGAR 719

Query: 2406 KN--KVIFVISAGETNSLDKDVLRNVSLRAKCQG---YSIFVFSFGPKHNDKELEELASH 2460
             N  K + +I+ GE     +D+++  ++  + +G   YS+ VF      N  +LEE++  
Sbjct: 720  PNIRKFLILITDGEA----QDIVKEPAVVLRQEGVIIYSVGVFG----SNVTQLEEISGR 771

Query: 2461 P 2461
            P
Sbjct: 772  P 772



 Score = 38.9 bits (89), Expect = 0.065
 Identities = 36/161 (22%), Positives = 76/161 (47%), Gaps = 25/161 (15%)

Query: 2290 MDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPN 2349
            +D+ FL+D S  +  ++FK++K F+ SV+  F ++   +      R+    +S   Y P 
Sbjct: 999  VDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRV------RIGAAQFSDT-YHP- 1050

Query: 2350 TEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLRKN-- 2407
                    EF L T+    ++   +++ +Q+ G+  IG AL+  +++ F      R N  
Sbjct: 1051 --------EFPLGTFIGEKEISFQIENIKQIFGNTHIGAALR-EVEHYFRPDMGSRINTG 1101

Query: 2408 --KVIFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFG 2446
              +V+ V++ G++    +D +   +   + +G  I+    G
Sbjct: 1102 TPQVLLVLTDGQS----QDEVAQAAEALRHRGIDIYSVGIG 1138



 Score = 37.4 bits (85), Expect = 0.19
 Identities = 34/138 (24%), Positives = 63/138 (45%), Gaps = 21/138 (15%)

Query: 2290 MDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPN 2349
            +DV F+ID+S  +  DE+  +K F+  ++    +    +      R   L Y+      +
Sbjct: 808  LDVVFVIDSSGSIDYDEYNIMKDFMIGLVKKADVGKNQV------RFGALKYA------D 855

Query: 2350 TEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLRKNK- 2408
              E   YL+     + +  ++   LQ+ Q + G  +   AL ++ D++F      R NK 
Sbjct: 856  DPEVLFYLD----DFGTKLEVISVLQNDQAMGGSTYTAEALGFS-DHMFTEARGSRLNKG 910

Query: 2409 ---VIFVISAGETNSLDK 2423
               V+ VI+ GE++  DK
Sbjct: 911  VPQVLIVITDGESHDADK 928


>gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo
            sapiens]
          Length = 2971

 Score = 1032 bits (2668), Expect = 0.0
 Identities = 706/2188 (32%), Positives = 1101/2188 (50%), Gaps = 127/2188 (5%)

Query: 30   DVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHSEFHLSTFKG 89
            D++FL+D S ++G  +FP+V+ F+  ++NSL I  +  RV L Q+SD   +EF L+T++ 
Sbjct: 433  DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQT 492

Query: 90   RSPMLNHLKKNFQFIGGS-LQIGKALQEAHRTYFSAPINGRDRKQFPPILVVLASAESED 148
            +S +L HL++  Q  GGS L  G AL   +  +F+     R R+  P +L++L + +SED
Sbjct: 493  KSDILGHLRQ-LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSED 551

Query: 149  EVEEASKALQKDGVKIISVGVQKASEENLKAMATSHFHFNLRTIRDLSTFSQNMTQIIKD 208
               +A+ AL + G+    VG  +A++  L+ +A +     L  + D S+      Q+I+ 
Sbjct: 552  SYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYL--MDDFSSLPALPQQLIQP 609

Query: 209  VTKYKEGAVDADMQVHFPISCQKDSLADLVFLVDESLGTGGNLRHLQTFLENITSSMDVK 268
            +T Y  G V+       P++ Q +S  D++FL D S    G    ++ FL  I   ++VK
Sbjct: 610  LTTYVSGGVE-----EVPLA-QPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVK 663

Query: 269  ENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQIKNLSIQVGKS-NTGAAIDQMRRDGFS 327
                R+ +  YS+  K  S      ++ E    +K + I+ GK+ N G A+D  +R  F 
Sbjct: 664  PEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFV 723

Query: 328  ESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNLRLEDVNVFALSIQGANNTQLEEIVSY 387
            +S GSR   GV Q  VL+    S D V   A NL+   V  F    + A+  +LE+IV  
Sbjct: 724  KSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLS 783

Query: 388  PPE-QTISTLKSYADLETYSTKFLKKLQNEIWSQISTYAEQRNLDKTGCVDTKEADIHFL 446
            P       +L    DL       LK + N   + +S                 E D+ FL
Sbjct: 784  PAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSG----------------EKDVVFL 827

Query: 447  IDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFYITDYSNDIDLR 506
            +DGS  ++   F  +K F+  V E   +G D+VRV VVQYSD T  EFY+  Y N  D+ 
Sbjct: 828  LDGSEGVRSG-FPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVV 886

Query: 507  KAIFNIKQLTGGT-YTGKALDYILQ-IIKNGMKDRMSK-VPCYLIVLTDGMSTDRVVEPA 563
             A+  +  L G T  TG AL+++L+ I+ +    R+++ VP  LIVLT   S D V  P+
Sbjct: 887  NAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPS 946

Query: 564  KRLRAEQITVHAVGIGAANKIELQEIAGKEERVSFGQNFDALKSIKNEVVREICAEKGCE 623
              ++        +GIG A+  E+Q I+   +       F  L +++ +V+ E   +   E
Sbjct: 947  VVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQ-QVISERVTQLTRE 1005

Query: 624  DM-----------------KADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGADKTQ 666
            ++                 K D++FL+D S S G E F+ ++  ++ L+  + +G D T+
Sbjct: 1006 ELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTR 1064

Query: 667  IGVVQFSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTLT-GKALNFVGQ-YFTHSKGA 724
            + V+QFSD  K EF LN + ++ E+ +A+ R+       +  G AL +V +  F    G+
Sbjct: 1065 VAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGS 1124

Query: 725  RL--GAKKFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGDSSLVF 782
            R+  G  +FL+LI+ G + D+V DPA  L+   V  F++   NA++ +L +IS     VF
Sbjct: 1125 RIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIA-RNADQEELVKISLSPEYVF 1183

Query: 783  HVENFDHLKALERKLIFRVCALHDCKRITLL---------------DVVFVLDHSGSIKK 827
             V  F  L +LE+KL+  +  L   +   LL               D+VF++D S  ++ 
Sbjct: 1184 SVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRP 1243

Query: 828  QYQDHMINLTIHLVKKADVGRDRVQFGALKYSDQPNILFYLNTYSNRSAIIENLRKRRDT 887
                H+ +    +V++ ++G  +V+ G +++S+     FYL TY +++ +++ +R+ R  
Sbjct: 1244 DGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLR 1303

Query: 888  GGNTY-TAKALKH-ANALFTEEHGSRIKQNVKQMLIVITDGESHDHDQLNDTALELRNKG 945
            GG+   T KAL+  A  LF +  GSRI+  V Q L+++  G+S D   ++  A  +R+ G
Sbjct: 1304 GGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQD--DVSRFAQVIRSSG 1361

Query: 946  ITIFAVGVGKANQKELEGMAGNKNNTIYVDNFDKLKDVFTLVQER------------MCT 993
            I    VG    ++ EL+ +  +      V  F +L ++   +               + T
Sbjct: 1362 IVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDT 1421

Query: 994  EAPEVCHLQEADVIFLCDGSDRVSNSDFVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSNY 1053
              P     ++AD++FL DGS       F  +  F+S+++D        +++G+ Q+ S+ 
Sbjct: 1422 PPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDP 1481

Query: 1054 QSIIELKNSLTKTQWKTQIQNVSKSGG-FPRIDFALKKVS-NMFNLHAGGRRNAGVPQTL 1111
                 LK+  TK Q    I  V   GG        L+ +  N F   AG R +  VPQ  
Sbjct: 1482 TDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIA 1541

Query: 1112 VVITSGDPRYDVADAVKTLKDLGICVLVLGIGDVYKEHLLPITGNSEKIITFQDFDKLKN 1171
             VIT G    D  D    L   G+ V  +G+ ++  E +  I  NS       +  +L  
Sbjct: 1542 FVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELS- 1600

Query: 1172 VDVKKRIIREICQSCGKT----------NCFMDIVVGFDISTHVQGQPLFQGHPQLESYL 1221
             ++ ++++  +  +  +T           C +D+++GFD S   + Q +F      ES +
Sbjct: 1601 -ELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGS---RDQNVFVAQKGFESKV 1656

Query: 1222 PGILEDISSIKGVSCGAGTEAQVSLAFKVNSDQGFPAKFQI--YQKAVFDSLLQVNVSGP 1279
              IL  IS +  VSC  G    V ++   N+  G    F    YQ  + +    +    P
Sbjct: 1657 DAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQHP 1716

Query: 1280 THLNAQFLRSLWDTFKDKSASRGQVLLIFSDGLQSESNIMLENQSDRLREAGLDALLVVS 1339
              L    L+   + F+  S    +V++ F+DG   +    L   S+ LR+ G+ AL++V 
Sbjct: 1717 YVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDL-ADLHRASENLRQEGVRALILVG 1775

Query: 1340 LNTTAHHE-FSSFEFGKRFDYRTHLTIGMRELGKKLSQYLGNIAERTCCCTFCKCPGIPG 1398
            L    + E     EFG+ F Y   L + + +L  +L++ L NIAE+ CC   CKC G  G
Sbjct: 1776 LERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQRG 1835

Query: 1399 PHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFSG 1458
              G  G    KG  G  G RG+ G++G PG RG  G  G +G  GCPG  G KG +GF G
Sbjct: 1836 DRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPG 1895

Query: 1459 PKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPG 1518
             KG  G+ G+DGLDGE+G  G PG  GEKG+PG +G  G RG  G+ G+ G  GDPGNPG
Sbjct: 1896 EKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPG 1955

Query: 1519 QNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGTL 1578
            Q++  +G KG  G+ G  G  G+ GV G P   G  G  G+RG  G  G  G PG  G  
Sbjct: 1956 QDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFE 2015

Query: 1579 GAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDL 1638
            G +G +G QG  G  G  G  G QG  GP+GS G  GA G  GR G LG+KGEPG PG  
Sbjct: 2016 GEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPK 2075

Query: 1639 GPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRG 1698
            G +G  G RG  GD G  G G  GR+G KG RGFPG  G KG+ G PG+ G  GPKG RG
Sbjct: 2076 GGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRG 2135

Query: 1699 LALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCDLIRFLREHSPC--WKEKCPAYP 1756
                 G  G  G +G PG PG  G KG  G  +  QC LI+ +++  PC     +CP +P
Sbjct: 2136 RRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSI-DQCALIQSIKDKCPCCYGPLECPVFP 2194

Query: 1757 TELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNSGTSYLIRW 1816
            TEL FALD S  V +++F + RD++ SIVNDL I E+NCP GARVA+V+YN+  +  IR+
Sbjct: 2195 TELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRF 2254

Query: 1817 SDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYAGANVRRVAVFFSNGQT 1876
            +D  RK  LL ++  ++   T++ + +  AM FV RN FKR   G  +R+VAVFFSN  T
Sbjct: 2255 ADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPT 2314

Query: 1877 ASRSSIITATMEFSALDISPTVFAFDE-RVFLEAFGFDNTGTFQVIPVPPNGE-NQTLER 1934
             +   +  A ++ S   I+P      E R  + A   +NT     + +P   +    LE 
Sbjct: 2315 RASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLEN 2374

Query: 1935 LRRCALCYDKC-FPNACIREAFLP---------EDSYMDVVFLIDNSRNIAKDEFKAVKA 1984
            +  C +C D C    +C   ++ P          D  +D+ F++D++      +F  +K 
Sbjct: 2375 VLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKK 2434

Query: 1985 LVSSVIDNFNIASDPLISDSGDRIALLSYSPWES-SRRKMGTVKTEFDFITYDNQLLMKN 2043
             ++ ++   +++ DP  S    R+A++ ++P ES     M  VK EF    Y ++  + +
Sbjct: 2435 YIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVD 2494

Query: 2044 HIQTSFQQLNGEATIGRALLWTTENLFPETPYLRKHKVIFVVSAGENYERK-EFVKMMAL 2102
             +     QL G   +G A+ +T EN+F   P  R  K++ ++  GE  E++ E  + + L
Sbjct: 2495 FLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVIL 2554

Query: 2103 RAKCQGYVIFVISLGSTRKDDMEELASY 2130
            +AKC+GY  F + LG  RK +++E+ ++
Sbjct: 2555 QAKCKGY--FFVVLGIGRKVNIKEVYTF 2580



 Score =  393 bits (1009), Expect = e-108
 Identities = 318/1189 (26%), Positives = 571/1189 (48%), Gaps = 68/1189 (5%)

Query: 29   ADVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHSEFHLSTFK 88
            AD++FL+D S++ G  +F  +  F+  ++  LPI   + RV + Q+SDE  + F L T+ 
Sbjct: 35   ADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYS 94

Query: 89   GRSPMLNHLKKNFQFIGGSL-QIGKALQEAHRTYFSAPINGRDRKQFPPILVVLASAESE 147
             ++ +L  +K    F GG L  IG AL      +F+     R  +  P +LV++++  S 
Sbjct: 95   TKAQVLGAVKA-LGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSS 153

Query: 148  DEVEEASKALQKDGVKIISVGVQKASEENLKAMAT-SHFHFNLRTIRDLSTFSQNMTQII 206
            DE+     AL++  V    +G Q AS   L+ +AT  +  F +   R      + +   I
Sbjct: 154  DEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYI 213

Query: 207  KDVTKYKEGAVDADMQVHFPISCQKDSLADLVFLVDESLGTG-GNLRHLQTFLENITSSM 265
              V + +   +     V   I   K    D+VFLVD S   G  N   ++ F+  +   +
Sbjct: 214  VGVAQ-RHIVLKPPTIVTQVIEVNK---RDIVFLVDGSSALGLANFNAIRDFIAKVIQRL 269

Query: 266  DVKENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQIKNLSIQVGKS-NTGAAIDQMRRD 324
            ++ ++ +++ +  Y+++ +   +  +  T+ E    ++ +    G +  TG+A+D +R +
Sbjct: 270  EIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNN 329

Query: 325  GFSESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNLRLEDVNVFALSIQGANNTQLEEI 384
             F+ S G R A+G+P++ VL+T   S DE+   A  L+   +  FA+  +GA+  +LEEI
Sbjct: 330  LFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEI 389

Query: 385  VSYPPEQTISTLKSYADLETYSTKFLKKLQNEIWSQISTYAEQRNLDKTGCVDTKEADIH 444
                    I      A L+      L  L              R L  T  V + + DI 
Sbjct: 390  AFDSSLVFIPAEFRAAPLQGMLPGLLAPL--------------RTLSGTPEVHSNKRDII 435

Query: 445  FLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFYITDYSNDID 504
            FL+DGS+++ +  F  ++ F++ +     IG D +RVG+VQ+SD    EF +  Y    D
Sbjct: 436  FLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSD 495

Query: 505  LRKAIFNIKQLTGGT--YTGKALDYIL--QIIKNGMKDRMSKVPCYLIVLTDGMSTDRVV 560
            +   +  + QL GG+   TG AL Y+      + G       VP  L++LT G S D  +
Sbjct: 496  ILGHLRQL-QLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYL 554

Query: 561  EPAKRLRAEQITVHAVGIGAANKIELQEIAGKEERVSFGQNFDALKSIKNEVVREIC--A 618
            + A  L    I    VG   ANK EL++IA     V    +F +L ++  ++++ +    
Sbjct: 555  QAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYV 614

Query: 619  EKGCEDM-------KADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGADKTQIGVVQ 671
              G E++       K DI+FL D S ++  + F  ++ F+  ++ ++ +  + T+I V Q
Sbjct: 615  SGGVEEVPLAQPESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAVAQ 673

Query: 672  FSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTLT-GKALNFVGQY-FTHSKGARL--G 727
            +SD  K E + + + ++ EI + + RM +     L  G AL++  +Y F  S G+R+  G
Sbjct: 674  YSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDG 733

Query: 728  AKKFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGDSSLVFHVENF 787
              +FL+L+  G + D V  PA  L+   V  F     NA+ ++LE+I    + +   E+ 
Sbjct: 734  VLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESL 793

Query: 788  DHLKALERKLIFRVCALHDCKRITL---LDVVFVLDHSGSIKKQYQDHMINLTIHLVKKA 844
              +  L  +++  + ++H+     +    DVVF+LD S  ++  +   +      +V+  
Sbjct: 794  PKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVRSGF-PLLKEFVQRVVESL 852

Query: 845  DVGRDRVQFGALKYSDQPNILFYLNTYSNRSAIIENLRKRRDTGGNT-YTAKALKHA-NA 902
            DVG+DRV+   ++YSD+    FYLN+Y N+  ++  +R+    GG T  T  AL+     
Sbjct: 853  DVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRN 912

Query: 903  LFTEEHGSRIKQNVKQMLIVITDGESHDHDQLNDTALELRNKGITIFAVGVGKANQKELE 962
            +     GSRI + V Q+LIV+T   S   D + + ++ ++  G     +G+G A+  E++
Sbjct: 913  ILVSSAGSRITEGVPQLLIVLTADRS--GDDVRNPSVVVKRGGAVPIGIGIGNADITEMQ 970

Query: 963  GMAGNKNNTIYVDNFDKLKDVFTLVQERMC-TEAPEVCHLQ-------------EADVIF 1008
             ++   +  + +  F +L  V  ++ ER+      E+  LQ             + DV+F
Sbjct: 971  TISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVF 1030

Query: 1009 LCDGSDRVSNSDFVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSNYQSIIELKNSLTKTQW 1068
            L DGS + +  +F  + T +  L+D  D+     ++ + QF  + +    L    +K + 
Sbjct: 1031 LIDGS-QSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEV 1089

Query: 1069 KTQIQNVSKSGGFP-RIDFALKKVS-NMFNLHAGGRRNAGVPQTLVVITSGDPRYDVADA 1126
            +  +Q +   GG    +  AL+ VS N+F    G R   GVPQ LV+I+SG    +V D 
Sbjct: 1090 QNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDP 1149

Query: 1127 VKTLKDLGICVLVLGIGDVYKEHLLPITGNSEKIITFQDFDKLKNVDVK 1175
               LK  G+    +   +  +E L+ I+ + E + +   F +L +++ K
Sbjct: 1150 AVELKQFGVAPFTIA-RNADQEELVKISLSPEYVFSVSTFRELPSLEQK 1197



 Score =  299 bits (766), Expect = 2e-80
 Identities = 273/1049 (26%), Positives = 483/1049 (46%), Gaps = 90/1049 (8%)

Query: 21   SPGPGPVYADVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHS 80
            +P P     DVVFL+D S+ +    FP +K F+ +++ SL +  ++ RVA+ QYSD    
Sbjct: 814  APAPVSGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRP 872

Query: 81   EFHLSTFKGRSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRKQFPPILVV 140
            EF+L+++  +  ++N +++     G +   G AL+   R    +    R  +  P +L+V
Sbjct: 873  EFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIV 932

Query: 141  LASAESEDEVEEASKALQKDGVKIISVGVQKASEENLKAMA-TSHFHFNLRTIRDLSTFS 199
            L +  S D+V   S  +++ G   I +G+  A    ++ ++    F   + T R L T  
Sbjct: 933  LTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQ 992

Query: 200  QNMTQIIKDVTKYKEGAVDADMQVHFPI-SCQKDSLADLVFLVDESLGTGGNLRHLQTFL 258
            Q +++ +  +T+ +   +   +Q   P+ S       D+VFL+D S   G   ++++T +
Sbjct: 993  QVISERVTQLTREELSRLQPVLQ---PLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLI 1049

Query: 259  ENITSSMDVKENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQIKNLSIQVGKS-NTGAA 317
            E +   +DV  +  R+ ++ +S+  K    L + +++ E Q  ++ L  + G+  N G A
Sbjct: 1050 ERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNA 1109

Query: 318  IDQMRRDGFSESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNLRLEDVNVFALSIQGAN 377
            ++ + R+ F    GSR  +GVPQ  VL++   SDDEV D A+ L+   V  F +    A 
Sbjct: 1110 LEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI----AR 1165

Query: 378  NTQLEEIV--SYPPEQTISTLKSYADLETYSTKFLKKLQNEIWSQISTYAEQRNLDKTGC 435
            N   EE+V  S  PE   S + ++ +L +   K L  +      QI              
Sbjct: 1166 NADQEELVKISLSPEYVFS-VSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPP-A 1223

Query: 436  VDTKEADIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFY 495
            V++  ADI FLID S  ++   F  I+ F+  +    +IGP KVRVGVVQ+S+D   EFY
Sbjct: 1224 VESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFY 1283

Query: 496  ITDYSNDIDLRKAIFNIKQLTGGT--YTGKALDYILQ--IIKNGMKDRMSKVPCYLIVLT 551
            +  Y +   +  AI  ++ L GG+   TGKAL+++ +   +K+        VP +L+++ 
Sbjct: 1284 LKTYRSQAPVLDAIRRLR-LRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVL 1342

Query: 552  DGMSTDRVVEPAKRLRAEQITVHAVGIGAANKIELQEIAGKEERVSFGQNFDALKSIKNE 611
             G S D V   A+ +R+  I    VG    ++ ELQ I      V   + F  L +I+  
Sbjct: 1343 GGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEER 1402

Query: 612  VVREICAEKGC--------------EDMKADIMFLVDSSWSIGNENFRKMKIFMKNLLTK 657
            ++                       E  KADI+FL+D S +   ++F+++  F+  ++  
Sbjct: 1403 IMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDT 1462

Query: 658  IQIGADKTQIGVVQFSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTLTGKALNF-VG- 715
            +    D  Q+G+VQ++    +EF L  + T+++I DAI++  ++ +G   G+  N  VG 
Sbjct: 1463 VYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINK--VVYKG---GRHANTKVGL 1517

Query: 716  -----QYFTHSKGARLGAK--KFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANR 768
                  +F    G+RL  +  +   +IT G + +D +D +  L  + V +F+VGV N + 
Sbjct: 1518 EHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDS 1577

Query: 769  SQLEEISGDSSLVFHVENFDHLKALERKLIFRVCALHDCKRITL------------LDVV 816
             ++ +I+ +S+  F V N   L  L  +++     LHD    TL            LDV+
Sbjct: 1578 EEVGKIASNSATAFRVGNVQELSELSEQVLE---TLHDAMHETLCPGVTDAAKACNLDVI 1634

Query: 817  FVLDHSGS-----IKKQYQ---DHMIN--LTIHLVKKADVGRDRVQFGALKYSDQ-PNIL 865
               D S        +K ++   D ++N    +H V  +      V+   +  +   P   
Sbjct: 1635 LGFDGSRDQNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEA 1694

Query: 866  FYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKHANALFTEEHGSRIKQNVKQMLIVITD 925
            F  + Y  +  ++E  R  R       T   LK     F +     +K     ++I  TD
Sbjct: 1695 FDFDEY--QPEMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVK-----VVIHFTD 1747

Query: 926  GESHDHDQLNDTALELRNKGI-TIFAVGVGKANQKE----LE-GMAGNKNNTIYVDNFD- 978
            G   D   L+  +  LR +G+  +  VG+ +    E    LE G     +  + ++  D 
Sbjct: 1748 GADGDLADLHRASENLRQEGVRALILVGLERVVNLERLMHLEFGRGFMYDRPLRLNLLDL 1807

Query: 979  --KLKDVFTLVQERMCTEAPEVCHLQEAD 1005
              +L +    + E+ C   P  C  Q  D
Sbjct: 1808 DYELAEQLDNIAEKACCGVPCKCSGQRGD 1836



 Score =  101 bits (252), Expect = 8e-21
 Identities = 62/219 (28%), Positives = 110/219 (50%), Gaps = 1/219 (0%)

Query: 2290 MDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPN 2349
            +D+AF++D+++     +F E+K +I  ++    ++P P  S    RVAV+ ++P   + N
Sbjct: 2412 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2471

Query: 2350 TEECPVYLEFDLVTYNSIHQMKHHLQDSQ-QLNGDVFIGHALQWTIDNVFVGTPNLRKNK 2408
                PV +EF L  Y S  ++   L     QL G   +G A+++TI+NVF   PN R  K
Sbjct: 2472 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLK 2531

Query: 2409 VIFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHNDKELEELASHPLDHHLVQ 2468
            ++ ++  GE      +  + V L+AKC+GY   V   G K N KE+   AS P D     
Sbjct: 2532 IVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKL 2591

Query: 2469 LGRTHKPDWNYIIKFVKPFVHLIRRAINKYPTEDMKATC 2507
            + ++ + +   +++F +     +      Y + D++  C
Sbjct: 2592 VDKSTELNEEPLMRFGRLLPSFVSSENAFYLSPDIRKQC 2630



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 81/390 (20%), Positives = 155/390 (39%), Gaps = 54/390 (13%)

Query: 1758 ELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGA---RVAMVSYNSGTSYLI 1814
            +++F +D S +    +F    D + +++  L       P+G    RV +V ++     + 
Sbjct: 36   DIIFLIDGSNNTGSVNFAVILDFLVNLLEKL-------PIGTQQIRVGVVQFSDEPRTMF 88

Query: 1815 RWSDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYAGA---NVRRVAVFF 1871
                Y+ K Q+L  +  + +    E  ++G A+ FV  N F R         V +V V  
Sbjct: 89   SLDTYSTKAQVLGAVKALGFAGG-ELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLI 147

Query: 1872 SNGQTASRSSIITATMEFSALDISPTVFAFD------ERVFLEAFGFDNTGTFQVIPVPP 1925
            S G ++         ++        +VF+F        R  L+    D+   F V     
Sbjct: 148  SAGPSSDEIRYGVVALK------QASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRS 201

Query: 1926 NGENQT--LERLRRCALCYDKCFPNACIREAFLPEDSYMDVVFLIDNSRNIAKDEFKAVK 1983
             G+ Q   L  +   A  +    P   + +    E +  D+VFL+D S  +    F A++
Sbjct: 202  FGDLQEKLLPYIVGVAQRHIVLKPPTIVTQVI--EVNKRDIVFLVDGSSALGLANFNAIR 259

Query: 1984 ALVSSVIDNFNIASDPLISDSGDRIALLSYSPWESSRRKMGTVKTEFDFITYDNQLLMKN 2043
              ++ VI    I  D +      ++A+  Y+          TV+ EF F T+  +  +  
Sbjct: 260  DFIAKVIQRLEIGQDLI------QVAVAQYA---------DTVRPEFYFNTHPTKREVIT 304

Query: 2044 HIQTSFQQLNGEAT-IGRALLWTTENLFPETPYLRK----HKVIFVVSAGENYERKEFVK 2098
             ++   + L+G A   G AL +   NLF  +   R      K++ +++ G++ +    + 
Sbjct: 305  AVR-KMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDE---IS 360

Query: 2099 MMALRAKCQGYVIFVISLGSTRKDDMEELA 2128
              A   K    + F I      + ++EE+A
Sbjct: 361  QPAQELKRSSIMAFAIGNKGADQAELEEIA 390



 Score = 38.1 bits (87), Expect = 0.11
 Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 17/116 (14%)

Query: 2291 DVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPNT 2350
            D+ FLID+S+ V  D F  ++ F++ ++   +I P+ +      RV V+ +S        
Sbjct: 1230 DIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKV------RVGVVQFSN------- 1276

Query: 2351 EECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGD-VFIGHALQWTIDNVFVGTPNLR 2405
                V+ EF L TY S   +   ++  +   G  +  G AL++   N+FV +   R
Sbjct: 1277 ---DVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSR 1329


>gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
            sapiens]
          Length = 3177

 Score = 1032 bits (2668), Expect = 0.0
 Identities = 706/2188 (32%), Positives = 1101/2188 (50%), Gaps = 127/2188 (5%)

Query: 30   DVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHSEFHLSTFKG 89
            D++FL+D S ++G  +FP+V+ F+  ++NSL I  +  RV L Q+SD   +EF L+T++ 
Sbjct: 639  DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQT 698

Query: 90   RSPMLNHLKKNFQFIGGS-LQIGKALQEAHRTYFSAPINGRDRKQFPPILVVLASAESED 148
            +S +L HL++  Q  GGS L  G AL   +  +F+     R R+  P +L++L + +SED
Sbjct: 699  KSDILGHLRQ-LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSED 757

Query: 149  EVEEASKALQKDGVKIISVGVQKASEENLKAMATSHFHFNLRTIRDLSTFSQNMTQIIKD 208
               +A+ AL + G+    VG  +A++  L+ +A +     L  + D S+      Q+I+ 
Sbjct: 758  SYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYL--MDDFSSLPALPQQLIQP 815

Query: 209  VTKYKEGAVDADMQVHFPISCQKDSLADLVFLVDESLGTGGNLRHLQTFLENITSSMDVK 268
            +T Y  G V+       P++ Q +S  D++FL D S    G    ++ FL  I   ++VK
Sbjct: 816  LTTYVSGGVE-----EVPLA-QPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVK 869

Query: 269  ENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQIKNLSIQVGKS-NTGAAIDQMRRDGFS 327
                R+ +  YS+  K  S      ++ E    +K + I+ GK+ N G A+D  +R  F 
Sbjct: 870  PEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFV 929

Query: 328  ESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNLRLEDVNVFALSIQGANNTQLEEIVSY 387
            +S GSR   GV Q  VL+    S D V   A NL+   V  F    + A+  +LE+IV  
Sbjct: 930  KSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLS 989

Query: 388  PPE-QTISTLKSYADLETYSTKFLKKLQNEIWSQISTYAEQRNLDKTGCVDTKEADIHFL 446
            P       +L    DL       LK + N   + +S                 E D+ FL
Sbjct: 990  PAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSG----------------EKDVVFL 1033

Query: 447  IDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFYITDYSNDIDLR 506
            +DGS  ++   F  +K F+  V E   +G D+VRV VVQYSD T  EFY+  Y N  D+ 
Sbjct: 1034 LDGSEGVRSG-FPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVV 1092

Query: 507  KAIFNIKQLTGGT-YTGKALDYILQ-IIKNGMKDRMSK-VPCYLIVLTDGMSTDRVVEPA 563
             A+  +  L G T  TG AL+++L+ I+ +    R+++ VP  LIVLT   S D V  P+
Sbjct: 1093 NAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPS 1152

Query: 564  KRLRAEQITVHAVGIGAANKIELQEIAGKEERVSFGQNFDALKSIKNEVVREICAEKGCE 623
              ++        +GIG A+  E+Q I+   +       F  L +++ +V+ E   +   E
Sbjct: 1153 VVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQ-QVISERVTQLTRE 1211

Query: 624  DM-----------------KADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGADKTQ 666
            ++                 K D++FL+D S S G E F+ ++  ++ L+  + +G D T+
Sbjct: 1212 ELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTR 1270

Query: 667  IGVVQFSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTLT-GKALNFVGQ-YFTHSKGA 724
            + V+QFSD  K EF LN + ++ E+ +A+ R+       +  G AL +V +  F    G+
Sbjct: 1271 VAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGS 1330

Query: 725  RL--GAKKFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGDSSLVF 782
            R+  G  +FL+LI+ G + D+V DPA  L+   V  F++   NA++ +L +IS     VF
Sbjct: 1331 RIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIA-RNADQEELVKISLSPEYVF 1389

Query: 783  HVENFDHLKALERKLIFRVCALHDCKRITLL---------------DVVFVLDHSGSIKK 827
             V  F  L +LE+KL+  +  L   +   LL               D+VF++D S  ++ 
Sbjct: 1390 SVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRP 1449

Query: 828  QYQDHMINLTIHLVKKADVGRDRVQFGALKYSDQPNILFYLNTYSNRSAIIENLRKRRDT 887
                H+ +    +V++ ++G  +V+ G +++S+     FYL TY +++ +++ +R+ R  
Sbjct: 1450 DGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLR 1509

Query: 888  GGNTY-TAKALKH-ANALFTEEHGSRIKQNVKQMLIVITDGESHDHDQLNDTALELRNKG 945
            GG+   T KAL+  A  LF +  GSRI+  V Q L+++  G+S D   ++  A  +R+ G
Sbjct: 1510 GGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQD--DVSRFAQVIRSSG 1567

Query: 946  ITIFAVGVGKANQKELEGMAGNKNNTIYVDNFDKLKDVFTLVQER------------MCT 993
            I    VG    ++ EL+ +  +      V  F +L ++   +               + T
Sbjct: 1568 IVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDT 1627

Query: 994  EAPEVCHLQEADVIFLCDGSDRVSNSDFVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSNY 1053
              P     ++AD++FL DGS       F  +  F+S+++D        +++G+ Q+ S+ 
Sbjct: 1628 PPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDP 1687

Query: 1054 QSIIELKNSLTKTQWKTQIQNVSKSGG-FPRIDFALKKVS-NMFNLHAGGRRNAGVPQTL 1111
                 LK+  TK Q    I  V   GG        L+ +  N F   AG R +  VPQ  
Sbjct: 1688 TDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIA 1747

Query: 1112 VVITSGDPRYDVADAVKTLKDLGICVLVLGIGDVYKEHLLPITGNSEKIITFQDFDKLKN 1171
             VIT G    D  D    L   G+ V  +G+ ++  E +  I  NS       +  +L  
Sbjct: 1748 FVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELS- 1806

Query: 1172 VDVKKRIIREICQSCGKT----------NCFMDIVVGFDISTHVQGQPLFQGHPQLESYL 1221
             ++ ++++  +  +  +T           C +D+++GFD S   + Q +F      ES +
Sbjct: 1807 -ELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGS---RDQNVFVAQKGFESKV 1862

Query: 1222 PGILEDISSIKGVSCGAGTEAQVSLAFKVNSDQGFPAKFQI--YQKAVFDSLLQVNVSGP 1279
              IL  IS +  VSC  G    V ++   N+  G    F    YQ  + +    +    P
Sbjct: 1863 DAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQHP 1922

Query: 1280 THLNAQFLRSLWDTFKDKSASRGQVLLIFSDGLQSESNIMLENQSDRLREAGLDALLVVS 1339
              L    L+   + F+  S    +V++ F+DG   +    L   S+ LR+ G+ AL++V 
Sbjct: 1923 YVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDL-ADLHRASENLRQEGVRALILVG 1981

Query: 1340 LNTTAHHE-FSSFEFGKRFDYRTHLTIGMRELGKKLSQYLGNIAERTCCCTFCKCPGIPG 1398
            L    + E     EFG+ F Y   L + + +L  +L++ L NIAE+ CC   CKC G  G
Sbjct: 1982 LERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQRG 2041

Query: 1399 PHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFSG 1458
              G  G    KG  G  G RG+ G++G PG RG  G  G +G  GCPG  G KG +GF G
Sbjct: 2042 DRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPG 2101

Query: 1459 PKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPG 1518
             KG  G+ G+DGLDGE+G  G PG  GEKG+PG +G  G RG  G+ G+ G  GDPGNPG
Sbjct: 2102 EKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPG 2161

Query: 1519 QNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGTL 1578
            Q++  +G KG  G+ G  G  G+ GV G P   G  G  G+RG  G  G  G PG  G  
Sbjct: 2162 QDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFE 2221

Query: 1579 GAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDL 1638
            G +G +G QG  G  G  G  G QG  GP+GS G  GA G  GR G LG+KGEPG PG  
Sbjct: 2222 GEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPK 2281

Query: 1639 GPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRG 1698
            G +G  G RG  GD G  G G  GR+G KG RGFPG  G KG+ G PG+ G  GPKG RG
Sbjct: 2282 GGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRG 2341

Query: 1699 LALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCDLIRFLREHSPC--WKEKCPAYP 1756
                 G  G  G +G PG PG  G KG  G  +  QC LI+ +++  PC     +CP +P
Sbjct: 2342 RRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSI-DQCALIQSIKDKCPCCYGPLECPVFP 2400

Query: 1757 TELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNSGTSYLIRW 1816
            TEL FALD S  V +++F + RD++ SIVNDL I E+NCP GARVA+V+YN+  +  IR+
Sbjct: 2401 TELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRF 2460

Query: 1817 SDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYAGANVRRVAVFFSNGQT 1876
            +D  RK  LL ++  ++   T++ + +  AM FV RN FKR   G  +R+VAVFFSN  T
Sbjct: 2461 ADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPT 2520

Query: 1877 ASRSSIITATMEFSALDISPTVFAFDE-RVFLEAFGFDNTGTFQVIPVPPNGE-NQTLER 1934
             +   +  A ++ S   I+P      E R  + A   +NT     + +P   +    LE 
Sbjct: 2521 RASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLEN 2580

Query: 1935 LRRCALCYDKC-FPNACIREAFLP---------EDSYMDVVFLIDNSRNIAKDEFKAVKA 1984
            +  C +C D C    +C   ++ P          D  +D+ F++D++      +F  +K 
Sbjct: 2581 VLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKK 2640

Query: 1985 LVSSVIDNFNIASDPLISDSGDRIALLSYSPWES-SRRKMGTVKTEFDFITYDNQLLMKN 2043
             ++ ++   +++ DP  S    R+A++ ++P ES     M  VK EF    Y ++  + +
Sbjct: 2641 YIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVD 2700

Query: 2044 HIQTSFQQLNGEATIGRALLWTTENLFPETPYLRKHKVIFVVSAGENYERK-EFVKMMAL 2102
             +     QL G   +G A+ +T EN+F   P  R  K++ ++  GE  E++ E  + + L
Sbjct: 2701 FLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVIL 2760

Query: 2103 RAKCQGYVIFVISLGSTRKDDMEELASY 2130
            +AKC+GY  F + LG  RK +++E+ ++
Sbjct: 2761 QAKCKGY--FFVVLGIGRKVNIKEVYTF 2786



 Score =  416 bits (1070), Expect = e-115
 Identities = 316/1152 (27%), Positives = 574/1152 (49%), Gaps = 56/1152 (4%)

Query: 29   ADVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHSEFHLSTFK 88
            AD++FLVDSS  +G + F  V+ F+  ++ SL +  N +  AL Q++   H+EF L+T++
Sbjct: 38   ADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYR 97

Query: 89   GRSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRKQFPPILVVLASAESED 148
             +  +L+H+  N  +IGG+ Q GK L+   +++ +     R     P ++VVL    S+D
Sbjct: 98   TKQEVLSHI-SNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKD 156

Query: 149  EVEEASKALQKDGVKIISVGVQKASEENLKAMATSHFHFNLRTIRDLSTFSQNMTQIIKD 208
             +   S  L+   V + ++GV+ A E  LK +A+   + ++  + + ++    +  ++  
Sbjct: 157  GLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSC 216

Query: 209  VTKYKEGAVDADMQVHFPISCQKDSLADLVFLVDESLGTGG-NLRHLQTFLENITSSMDV 267
            V          D +    I+ Q    AD++FL+D S  TG  N   +  FL N+   + +
Sbjct: 217  VHSSVSPERAGDTETLKDITAQDS--ADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPI 274

Query: 268  KENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQIKNLSIQVGK-SNTGAAIDQMRRDGF 326
                +R+G++ +S+  +T+  L + +T+++    +K L    G+ +N G A+D +  + F
Sbjct: 275  GTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHF 334

Query: 327  SESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNLRLEDVNVFALSIQGANNTQLEEIVS 386
            + + GSR  +GVPQ+ VL++  PS DE+    + L+   V  F L  Q A+  +L+ I +
Sbjct: 335  TRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIAT 394

Query: 387  YPP-EQTISTLKSYADLETYSTKFLKKL-QNEIWSQISTYAEQRNLDKTGCVDTKEADIH 444
                  T+   +S+ DL+     ++  + Q  I  +  T   Q        ++  + DI 
Sbjct: 395  DDNLVFTVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIVTQ-------VIEVNKRDIV 447

Query: 445  FLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFYITDYSNDID 504
            FL+DGSS++    F  I+ F+ +V +   IG D ++V V QY+D    EFY   +    +
Sbjct: 448  FLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKRE 507

Query: 505  LRKAIFNIKQLTGGT-YTGKALDYIL-QIIKNGMKDRMSK-VPCYLIVLTDGMSTDRVVE 561
            +  A+  +K L G   YTG ALD++   +  +    R ++ +P  L+++T G S D + +
Sbjct: 508  VITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQ 567

Query: 562  PAKRLRAEQITVHAVGIGAANKIELQEIAGKEERVSFGQNFDA--LKSIKNEVVREICAE 619
            PA+ L+   I   A+G   A++ EL+EIA     V     F A  L+ +   ++  +   
Sbjct: 568  PAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTL 627

Query: 620  KGCEDM---KADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGADKTQIGVVQFSDKT 676
             G  ++   K DI+FL+D S ++G  NF  ++ F+ NL+  + IG D  ++G+VQFSD  
Sbjct: 628  SGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTP 687

Query: 677  KEEFQLNRYFTQQEISDAIDRMSLI-NEGTLTGKALNFV-GQYFTHSKGARL--GAKKFL 732
              EF LN Y T+ +I   + ++ L    G  TG AL++V   +FT + G+R+     + L
Sbjct: 688  VTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLL 747

Query: 733  ILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGDSSLVFHVENFDHLKA 792
            +L+T G ++D     A  L    +  F VG   AN+++LE+I+ + SLV+ +++F  L A
Sbjct: 748  LLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPA 807

Query: 793  LERKLIFRV------------CALHDCKRITLLDVVFVLDHSGSIKKQYQDHMINLTIHL 840
            L ++LI  +             A  + KR    D++F+ D S ++  Q+   + +    +
Sbjct: 808  LPQQLIQPLTTYVSGGVEEVPLAQPESKR----DILFLFDGSANLVGQF-PVVRDFLYKI 862

Query: 841  VKKADVGRDRVQFGALKYSDQPNILFYLNTYSNRSAIIENLRKRR--DTGGNTYTAKALK 898
            + + +V  +  +    +YSD   +    + + ++  I+ NL KR    TG       AL 
Sbjct: 863  IDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEIL-NLVKRMKIKTGKALNLGYALD 921

Query: 899  HANA-LFTEEHGSRIKQNVKQMLIVITDGESHDHDQLNDTALELRNKGITIFAVGVGKAN 957
            +A   +F +  GSRI+  V Q L+++  G S   D+++  A  L+  G+  F      A+
Sbjct: 922  YAQRYIFVKSAGSRIEDGVLQFLVLLVAGRS--SDRVDGPASNLKQSGVVPFIFQAKNAD 979

Query: 958  QKELEGMAGNKNNTIYVDNFDKLKDVFTLV---QERMCTEAPEVCHLQEADVIFLCDGSD 1014
              ELE +  +    +  ++  K+ D+   +    + +   AP      E DV+FL DGS+
Sbjct: 980  PAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVS-GEKDVVFLLDGSE 1038

Query: 1015 RVSNSDFVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSNYQSIIELKNSLTKTQWKTQIQN 1074
             V  S F  +  F+  ++++ D+   R+++ + Q+    +    L + + K      ++ 
Sbjct: 1039 GV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQ 1097

Query: 1075 VSKSGG-FPRIDFALKKV-SNMFNLHAGGRRNAGVPQTLVVITSGDPRYDVADAVKTLKD 1132
            ++  GG  P    AL+ V  N+    AG R   GVPQ L+V+T+     DV +    +K 
Sbjct: 1098 LTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKR 1157

Query: 1133 LGICVLVLGIGD 1144
             G   + +GIG+
Sbjct: 1158 GGAVPIGIGIGN 1169



 Score =  299 bits (766), Expect = 2e-80
 Identities = 273/1049 (26%), Positives = 483/1049 (46%), Gaps = 90/1049 (8%)

Query: 21   SPGPGPVYADVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHS 80
            +P P     DVVFL+D S+ +    FP +K F+ +++ SL +  ++ RVA+ QYSD    
Sbjct: 1020 APAPVSGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRP 1078

Query: 81   EFHLSTFKGRSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRKQFPPILVV 140
            EF+L+++  +  ++N +++     G +   G AL+   R    +    R  +  P +L+V
Sbjct: 1079 EFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIV 1138

Query: 141  LASAESEDEVEEASKALQKDGVKIISVGVQKASEENLKAMA-TSHFHFNLRTIRDLSTFS 199
            L +  S D+V   S  +++ G   I +G+  A    ++ ++    F   + T R L T  
Sbjct: 1139 LTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQ 1198

Query: 200  QNMTQIIKDVTKYKEGAVDADMQVHFPI-SCQKDSLADLVFLVDESLGTGGNLRHLQTFL 258
            Q +++ +  +T+ +   +   +Q   P+ S       D+VFL+D S   G   ++++T +
Sbjct: 1199 QVISERVTQLTREELSRLQPVLQ---PLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLI 1255

Query: 259  ENITSSMDVKENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQIKNLSIQVGKS-NTGAA 317
            E +   +DV  +  R+ ++ +S+  K    L + +++ E Q  ++ L  + G+  N G A
Sbjct: 1256 ERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNA 1315

Query: 318  IDQMRRDGFSESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNLRLEDVNVFALSIQGAN 377
            ++ + R+ F    GSR  +GVPQ  VL++   SDDEV D A+ L+   V  F +    A 
Sbjct: 1316 LEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI----AR 1371

Query: 378  NTQLEEIV--SYPPEQTISTLKSYADLETYSTKFLKKLQNEIWSQISTYAEQRNLDKTGC 435
            N   EE+V  S  PE   S + ++ +L +   K L  +      QI              
Sbjct: 1372 NADQEELVKISLSPEYVFS-VSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPP-A 1429

Query: 436  VDTKEADIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFY 495
            V++  ADI FLID S  ++   F  I+ F+  +    +IGP KVRVGVVQ+S+D   EFY
Sbjct: 1430 VESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFY 1489

Query: 496  ITDYSNDIDLRKAIFNIKQLTGGT--YTGKALDYILQ--IIKNGMKDRMSKVPCYLIVLT 551
            +  Y +   +  AI  ++ L GG+   TGKAL+++ +   +K+        VP +L+++ 
Sbjct: 1490 LKTYRSQAPVLDAIRRLR-LRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVL 1548

Query: 552  DGMSTDRVVEPAKRLRAEQITVHAVGIGAANKIELQEIAGKEERVSFGQNFDALKSIKNE 611
             G S D V   A+ +R+  I    VG    ++ ELQ I      V   + F  L +I+  
Sbjct: 1549 GGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEER 1608

Query: 612  VVREICAEKGC--------------EDMKADIMFLVDSSWSIGNENFRKMKIFMKNLLTK 657
            ++                       E  KADI+FL+D S +   ++F+++  F+  ++  
Sbjct: 1609 IMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDT 1668

Query: 658  IQIGADKTQIGVVQFSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTLTGKALNF-VG- 715
            +    D  Q+G+VQ++    +EF L  + T+++I DAI++  ++ +G   G+  N  VG 
Sbjct: 1669 VYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINK--VVYKG---GRHANTKVGL 1723

Query: 716  -----QYFTHSKGARLGAK--KFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANR 768
                  +F    G+RL  +  +   +IT G + +D +D +  L  + V +F+VGV N + 
Sbjct: 1724 EHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDS 1783

Query: 769  SQLEEISGDSSLVFHVENFDHLKALERKLIFRVCALHDCKRITL------------LDVV 816
             ++ +I+ +S+  F V N   L  L  +++     LHD    TL            LDV+
Sbjct: 1784 EEVGKIASNSATAFRVGNVQELSELSEQVLE---TLHDAMHETLCPGVTDAAKACNLDVI 1840

Query: 817  FVLDHSGS-----IKKQYQ---DHMIN--LTIHLVKKADVGRDRVQFGALKYSDQ-PNIL 865
               D S        +K ++   D ++N    +H V  +      V+   +  +   P   
Sbjct: 1841 LGFDGSRDQNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEA 1900

Query: 866  FYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKHANALFTEEHGSRIKQNVKQMLIVITD 925
            F  + Y  +  ++E  R  R       T   LK     F +     +K     ++I  TD
Sbjct: 1901 FDFDEY--QPEMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVK-----VVIHFTD 1953

Query: 926  GESHDHDQLNDTALELRNKGI-TIFAVGVGKANQKE----LE-GMAGNKNNTIYVDNFD- 978
            G   D   L+  +  LR +G+  +  VG+ +    E    LE G     +  + ++  D 
Sbjct: 1954 GADGDLADLHRASENLRQEGVRALILVGLERVVNLERLMHLEFGRGFMYDRPLRLNLLDL 2013

Query: 979  --KLKDVFTLVQERMCTEAPEVCHLQEAD 1005
              +L +    + E+ C   P  C  Q  D
Sbjct: 2014 DYELAEQLDNIAEKACCGVPCKCSGQRGD 2042



 Score =  142 bits (359), Expect = 3e-33
 Identities = 103/386 (26%), Positives = 181/386 (46%), Gaps = 18/386 (4%)

Query: 806  DCKRITLLDVVFVLDHSGSIKKQYQDHMINLTIHLVKKADVGRDRVQFGALKYSDQPNIL 865
            D K     D++F++D S +I +++   +      +VK   VG +   F  ++++  P+  
Sbjct: 31   DVKNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTE 90

Query: 866  FYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKH-ANALFTEEHGSRIKQNVKQMLIVIT 924
            F LNTY  +  ++ ++      GG   T K L++   +  T+  GSR    V Q+++V+T
Sbjct: 91   FLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLT 150

Query: 925  DGESHDHDQLNDTALELRNKGITIFAVGVGKANQKELEGMAGNKNN--TIYVDNFDKLKD 982
            DG  H  D L   + EL++  + +FA+GV  A++  L+ +A    N     ++NF  L D
Sbjct: 151  DG--HSKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHD 208

Query: 983  VF-TLVQERMCTEAPE----------VCHLQEADVIFLCDGSDRVSNSDFVTMTTFLSDL 1031
            +   LV     + +PE          +     AD+IFL DGS+   + +F  +  FL +L
Sbjct: 209  IVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNL 268

Query: 1032 IDNFDIQSQRMKIGMAQFGSNYQSIIELKNSLTKTQWKTQIQNVSKSGG-FPRIDFALK- 1089
            ++   I +Q++++G+ QF    +++  L    TK Q    ++ +  +GG    I  AL  
Sbjct: 269  LEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDF 328

Query: 1090 KVSNMFNLHAGGRRNAGVPQTLVVITSGDPRYDVADAVKTLKDLGICVLVLGIGDVYKEH 1149
             V N F    G R   GVPQ LV+I++G    ++   V  LK   +    LG     +  
Sbjct: 329  VVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAE 388

Query: 1150 LLPITGNSEKIITFQDFDKLKNVDVK 1175
            L  I  +   + T  +F    ++  K
Sbjct: 389  LQHIATDDNLVFTVPEFRSFGDLQEK 414



 Score =  101 bits (252), Expect = 8e-21
 Identities = 62/219 (28%), Positives = 110/219 (50%), Gaps = 1/219 (0%)

Query: 2290 MDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPN 2349
            +D+AF++D+++     +F E+K +I  ++    ++P P  S    RVAV+ ++P   + N
Sbjct: 2618 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2677

Query: 2350 TEECPVYLEFDLVTYNSIHQMKHHLQDSQ-QLNGDVFIGHALQWTIDNVFVGTPNLRKNK 2408
                PV +EF L  Y S  ++   L     QL G   +G A+++TI+NVF   PN R  K
Sbjct: 2678 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLK 2737

Query: 2409 VIFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHNDKELEELASHPLDHHLVQ 2468
            ++ ++  GE      +  + V L+AKC+GY   V   G K N KE+   AS P D     
Sbjct: 2738 IVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKL 2797

Query: 2469 LGRTHKPDWNYIIKFVKPFVHLIRRAINKYPTEDMKATC 2507
            + ++ + +   +++F +     +      Y + D++  C
Sbjct: 2798 VDKSTELNEEPLMRFGRLLPSFVSSENAFYLSPDIRKQC 2836



 Score = 55.1 bits (131), Expect = 9e-07
 Identities = 74/400 (18%), Positives = 151/400 (37%), Gaps = 59/400 (14%)

Query: 1758 ELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNSGTSYLIRWS 1817
            +++F +D+S+ + EE F   R+ +  +V  L + EN+       A+V +N         +
Sbjct: 39   DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGEND----FHFALVQFNGNPHTEFLLN 94

Query: 1818 DYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKR---TYAGANVRRVAVFFSNG 1874
             Y  K+++L  +S + Y   T     G  + ++ ++   +   + AG  V +V V  ++G
Sbjct: 95   TYRTKQEVLSHISNMSYIGGT--NQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDG 152

Query: 1875 QTASRSSIITATMEFSALDISPTVFAFDERVFLEAFGFDNTGTFQVIPVPPNGENQTLER 1934
               S+  +   + E  + D++      ++         D     ++   P N     LE 
Sbjct: 153  H--SKDGLALPSAELKSADVNVFAIGVEDA--------DEGALKEIASEPLNMHMFNLEN 202

Query: 1935 LRRCALCYDKCFPNACIREAFLPE-------------DSYMDVVFLIDNSRNIAKDEFKA 1981
                          +C+  +  PE                 D++FLID S N     F  
Sbjct: 203  FTSLHDIVGNLV--SCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAV 260

Query: 1982 VKALVSSVIDNFNIASDPLISDSGDRIALLSYSPWESSRRKMGTVKTEFDFITYDNQLLM 2041
            +   + ++++   I +  +      R+ ++ +S            +T F   TY  +  +
Sbjct: 261  ILDFLVNLLEKLPIGTQQI------RVGVVQFS---------DEPRTMFSLDTYSTKAQV 305

Query: 2042 KNHIQTSFQQLNGEATIGRALLWTTENLFPETPYLRKH----KVIFVVSAGENYERKEFV 2097
               ++         A IG AL +  EN F      R      +V+ ++SAG + +   + 
Sbjct: 306  LGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYG 365

Query: 2098 KMMALRAKCQGYVIFVISLGSTRKDDMEELASYPLDQHLI 2137
             +   +A      +F   LG+ +     EL     D +L+
Sbjct: 366  VVALKQAS-----VFSFGLGA-QAASRAELQHIATDDNLV 399



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 81/390 (20%), Positives = 155/390 (39%), Gaps = 54/390 (13%)

Query: 1758 ELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGA---RVAMVSYNSGTSYLI 1814
            +++F +D S +    +F    D + +++  L       P+G    RV +V ++     + 
Sbjct: 242  DIIFLIDGSNNTGSVNFAVILDFLVNLLEKL-------PIGTQQIRVGVVQFSDEPRTMF 294

Query: 1815 RWSDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYAGA---NVRRVAVFF 1871
                Y+ K Q+L  +  + +    E  ++G A+ FV  N F R         V +V V  
Sbjct: 295  SLDTYSTKAQVLGAVKALGFAGG-ELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLI 353

Query: 1872 SNGQTASRSSIITATMEFSALDISPTVFAFD------ERVFLEAFGFDNTGTFQVIPVPP 1925
            S G ++         ++        +VF+F        R  L+    D+   F V     
Sbjct: 354  SAGPSSDEIRYGVVALK------QASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRS 407

Query: 1926 NGENQT--LERLRRCALCYDKCFPNACIREAFLPEDSYMDVVFLIDNSRNIAKDEFKAVK 1983
             G+ Q   L  +   A  +    P   + +    E +  D+VFL+D S  +    F A++
Sbjct: 408  FGDLQEKLLPYIVGVAQRHIVLKPPTIVTQVI--EVNKRDIVFLVDGSSALGLANFNAIR 465

Query: 1984 ALVSSVIDNFNIASDPLISDSGDRIALLSYSPWESSRRKMGTVKTEFDFITYDNQLLMKN 2043
              ++ VI    I  D +      ++A+  Y+          TV+ EF F T+  +  +  
Sbjct: 466  DFIAKVIQRLEIGQDLI------QVAVAQYA---------DTVRPEFYFNTHPTKREVIT 510

Query: 2044 HIQTSFQQLNGEAT-IGRALLWTTENLFPETPYLRK----HKVIFVVSAGENYERKEFVK 2098
             ++   + L+G A   G AL +   NLF  +   R      K++ +++ G++ +    + 
Sbjct: 511  AVR-KMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDE---IS 566

Query: 2099 MMALRAKCQGYVIFVISLGSTRKDDMEELA 2128
              A   K    + F I      + ++EE+A
Sbjct: 567  QPAQELKRSSIMAFAIGNKGADQAELEEIA 596



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 39/192 (20%), Positives = 87/192 (45%), Gaps = 23/192 (11%)

Query: 1952 REAFLPEDSYMDVVFLIDNSRNIAKDEFKAVKALVSSVIDNFNIASDPLISDSGDRIALL 2011
            ++A +   +  D++FL+D+S  I ++ F+ V+  +  V+ +        + ++    AL+
Sbjct: 28   QQADVKNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSL------AVGENDFHFALV 81

Query: 2012 SYSPWESSRRKMGTVKTEFDFITYDNQLLMKNHIQTSFQQLNGEATIGRALLWTTENLFP 2071
             ++         G   TEF   TY  +  + +HI ++   + G    G+ L +  ++   
Sbjct: 82   QFN---------GNPHTEFLLNTYRTKQEVLSHI-SNMSYIGGTNQTGKGLEYIMQSHLT 131

Query: 2072 ETPYLRK----HKVIFVVSAGENYERKEFVKMMALRAKCQGYVIFVISLGSTRKDDMEEL 2127
            +    R      +VI V++ G +   K+ + + +   K     +F I +    +  ++E+
Sbjct: 132  KAAGSRAGDGVPQVIVVLTDGHS---KDGLALPSAELKSADVNVFAIGVEDADEGALKEI 188

Query: 2128 ASYPLDQHLIQL 2139
            AS PL+ H+  L
Sbjct: 189  ASEPLNMHMFNL 200



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 41/180 (22%), Positives = 79/180 (43%), Gaps = 19/180 (10%)

Query: 2291 DVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPNT 2350
            D+ FL+D+S  +G + F+ V+ F+  V+    +             A++ ++     P+T
Sbjct: 39   DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDF------HFALVQFNG---NPHT 89

Query: 2351 EECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLRKNKVI 2410
                   EF L TY +  ++  H+ +   + G    G  L++ + +        R    +
Sbjct: 90   -------EFLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGV 142

Query: 2411 FVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHNDK-ELEELASHPLDHHLVQL 2469
              +    T+   KD L   S  A+ +   + VF+ G +  D+  L+E+AS PL+ H+  L
Sbjct: 143  PQVIVVLTDGHSKDGLALPS--AELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNL 200



 Score = 38.1 bits (87), Expect = 0.11
 Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 17/116 (14%)

Query: 2291 DVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPNT 2350
            D+ FLID+S+ V  D F  ++ F++ ++   +I P+ +      RV V+ +S        
Sbjct: 1436 DIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKV------RVGVVQFSN------- 1482

Query: 2351 EECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGD-VFIGHALQWTIDNVFVGTPNLR 2405
                V+ EF L TY S   +   ++  +   G  +  G AL++   N+FV +   R
Sbjct: 1483 ---DVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSR 1535


>gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo
            sapiens]
          Length = 2570

 Score =  993 bits (2568), Expect = 0.0
 Identities = 689/2189 (31%), Positives = 1081/2189 (49%), Gaps = 135/2189 (6%)

Query: 30   DVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHSEFHLSTFKG 89
            D+VFLVD S  LG  +F  ++ FI K+I  L I  +  +VA+AQY+D    EF+ +T   
Sbjct: 38   DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 97

Query: 90   RSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRKQFPPILVVLASAESEDE 149
            +  ++  ++K     G +L  G AL       F++    R  +  P +LV++   +S DE
Sbjct: 98   KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDE 157

Query: 150  VEEASKALQKDGVKIISVGVQKASEENLKAMATSHFHFNLRTIRDLSTFSQNMTQIIKDV 209
            + + ++ L++  +   ++G + A +  L+ +A                F  ++  I  + 
Sbjct: 158  ISQPAQELKRSSIMAFAIGNKGADQAELEEIA----------------FDSSLVFIPAEF 201

Query: 210  TKYK-EGAVDADMQVHFPIS-CQKDSLADLVFLVDESLGTGGNLRHLQTFLENITSSMDV 267
                 +G +   +     +S   ++S  D++FL D S    G    ++ FL  I   ++V
Sbjct: 202  RAAPLQGMLPGLLAPLRTLSGTPEESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNV 261

Query: 268  KENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQIKNLSIQVGKS-NTGAAIDQMRRDGF 326
            K    R+ +  YS+  K  S      ++ E    +K + I+ GK+ N G A+D  +R  F
Sbjct: 262  KPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIF 321

Query: 327  SESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNLRLEDVNVFALSIQGANNTQLEEIVS 386
             +S GSR   GV Q  VL+    S D V   A NL+   V  F    + A+  +LE+IV 
Sbjct: 322  VKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVL 381

Query: 387  YPPE-QTISTLKSYADLETYSTKFLKKLQNEIWSQISTYAEQRNLDKTGCVDTKEADIHF 445
             P       +L    DL       LK + N   + +S                 E D+ F
Sbjct: 382  SPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSG----------------EKDVVF 425

Query: 446  LIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFYITDYSNDIDL 505
            L+DGS  ++   F  +K F+  V E   +G D+VRV VVQYSD T  EFY+  Y N  D+
Sbjct: 426  LLDGSEGVRSG-FPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDV 484

Query: 506  RKAIFNIKQLTGGT-YTGKALDYILQ-IIKNGMKDRMSK-VPCYLIVLTDGMSTDRVVEP 562
              A+  +  L G T  TG AL+++L+ I+ +    R+++ VP  LIVLT   S D V  P
Sbjct: 485  VNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNP 544

Query: 563  AKRLRAEQITVHAVGIGAANKIELQEIAGKEERVSFGQNFDALKSIKNEVVREICAEKGC 622
            +  ++        +GIG A+  E+Q I+   +       F  L +++ +V+ E   +   
Sbjct: 545  SVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQ-QVISERVTQLTR 603

Query: 623  EDM-----------------KADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGADKT 665
            E++                 K D++FL+D S S G E F+ ++  ++ L+  + +G D T
Sbjct: 604  EELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTT 662

Query: 666  QIGVVQFSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTLT-GKALNFVGQ-YFTHSKG 723
            ++ V+QFSD  K EF LN + ++ E+ +A+ R+       +  G AL +V +  F    G
Sbjct: 663  RVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLG 722

Query: 724  ARL--GAKKFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGDSSLV 781
            +R+  G  +FL+LI+ G + D+V DPA  L+   V  F++   NA++ +L +IS     V
Sbjct: 723  SRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIA-RNADQEELVKISLSPEYV 781

Query: 782  FHVENFDHLKALERKLIFRVCALHDCKRITLL---------------DVVFVLDHSGSIK 826
            F V  F  L +LE+KL+  +  L   +   LL               D+VF++D S  ++
Sbjct: 782  FSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVR 841

Query: 827  KQYQDHMINLTIHLVKKADVGRDRVQFGALKYSDQPNILFYLNTYSNRSAIIENLRKRRD 886
                 H+ +    +V++ ++G  +V+ G +++S+     FYL TY +++ +++ +R+ R 
Sbjct: 842  PDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRL 901

Query: 887  TGGNTY-TAKALKH-ANALFTEEHGSRIKQNVKQMLIVITDGESHDHDQLNDTALELRNK 944
             GG+   T KAL+  A  LF +  GSRI+  V Q L+++  G+S D   ++  A  +R+ 
Sbjct: 902  RGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQD--DVSRFAQVIRSS 959

Query: 945  GITIFAVGVGKANQKELEGMAGNKNNTIYVDNFDKLKDVFTLVQER------------MC 992
            GI    VG    ++ EL+ +  +      V  F +L ++   +               + 
Sbjct: 960  GIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVD 1019

Query: 993  TEAPEVCHLQEADVIFLCDGSDRVSNSDFVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSN 1052
            T  P     ++AD++FL DGS       F  +  F+S+++D        +++G+ Q+ S+
Sbjct: 1020 TPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSD 1079

Query: 1053 YQSIIELKNSLTKTQWKTQIQNVSKSGG-FPRIDFALKKVS-NMFNLHAGGRRNAGVPQT 1110
                  LK+  TK Q    I  V   GG        L+ +  N F   AG R +  VPQ 
Sbjct: 1080 PTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQI 1139

Query: 1111 LVVITSGDPRYDVADAVKTLKDLGICVLVLGIGDVYKEHLLPITGNSEKIITFQDFDKLK 1170
              VIT G    D  D    L   G+ V  +G+ ++  E +  I  NS       +  +L 
Sbjct: 1140 AFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELS 1199

Query: 1171 NVDVKKRIIREICQSCGKT----------NCFMDIVVGFDISTHVQGQPLFQGHPQLESY 1220
              ++ ++++  +  +  +T           C +D+++GFD S   + Q +F      ES 
Sbjct: 1200 --ELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGS---RDQNVFVAQKGFESK 1254

Query: 1221 LPGILEDISSIKGVSCGAGTEAQVSLAFKVNSDQGFPAKFQI--YQKAVFDSLLQVNVSG 1278
            +  IL  IS +  VSC  G    V ++   N+  G    F    YQ  + +    +    
Sbjct: 1255 VDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQH 1314

Query: 1279 PTHLNAQFLRSLWDTFKDKSASRGQVLLIFSDGLQSESNIMLENQSDRLREAGLDALLVV 1338
            P  L    L+   + F+  S    +V++ F+DG   +    L   S+ LR+ G+ AL++V
Sbjct: 1315 PYVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDL-ADLHRASENLRQEGVRALILV 1373

Query: 1339 SLNTTAHHE-FSSFEFGKRFDYRTHLTIGMRELGKKLSQYLGNIAERTCCCTFCKCPGIP 1397
             L    + E     EFG+ F Y   L + + +L  +L++ L NIAE+ CC   CKC G  
Sbjct: 1374 GLERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQR 1433

Query: 1398 GPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFS 1457
            G  G  G    KG  G  G RG+ G++G PG RG  G  G +G  GCPG  G KG +GF 
Sbjct: 1434 GDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFP 1493

Query: 1458 GPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNP 1517
            G KG  G+ G+DGLDGE+G  G PG  GEKG+PG +G  G RG  G+ G+ G  GDPGNP
Sbjct: 1494 GEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNP 1553

Query: 1518 GQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGT 1577
            GQ++  +G KG  G+ G  G  G+ GV G P   G  G  G+RG  G  G  G PG  G 
Sbjct: 1554 GQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGF 1613

Query: 1578 LGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGD 1637
             G +G +G QG  G  G  G  G QG  GP+GS G  GA G  GR G LG+KGEPG PG 
Sbjct: 1614 EGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGP 1673

Query: 1638 LGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFR 1697
             G +G  G RG  GD G  G G  GR+G KG RGFPG  G KG+ G PG+ G  GPKG R
Sbjct: 1674 KGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIR 1733

Query: 1698 GLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCDLIRFLREHSPC--WKEKCPAY 1755
            G     G  G  G +G PG PG  G KG  G  +  QC LI+ +++  PC     +CP +
Sbjct: 1734 GRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSI-DQCALIQSIKDKCPCCYGPLECPVF 1792

Query: 1756 PTELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNSGTSYLIR 1815
            PTEL FALD S  V +++F + RD++ SIVNDL I E+NCP GARVA+V+YN+  +  IR
Sbjct: 1793 PTELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIR 1852

Query: 1816 WSDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYAGANVRRVAVFFSNGQ 1875
            ++D  RK  LL ++  ++   T++ + +  AM FV RN FKR   G  +R+VAVFFSN  
Sbjct: 1853 FADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTP 1912

Query: 1876 TASRSSIITATMEFSALDISPTVFAFDE-RVFLEAFGFDNTGTFQVIPVPPNGE-NQTLE 1933
            T +   +  A ++ S   I+P      E R  + A   +NT     + +P   +    LE
Sbjct: 1913 TRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLE 1972

Query: 1934 RLRRCALCYDKC-FPNACIREAFLP---------EDSYMDVVFLIDNSRNIAKDEFKAVK 1983
             +  C +C D C    +C   ++ P          D  +D+ F++D++      +F  +K
Sbjct: 1973 NVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMK 2032

Query: 1984 ALVSSVIDNFNIASDPLISDSGDRIALLSYSPWES-SRRKMGTVKTEFDFITYDNQLLMK 2042
              ++ ++   +++ DP  S    R+A++ ++P ES     M  VK EF    Y ++  + 
Sbjct: 2033 KYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLV 2092

Query: 2043 NHIQTSFQQLNGEATIGRALLWTTENLFPETPYLRKHKVIFVVSAGENYERK-EFVKMMA 2101
            + +     QL G   +G A+ +T EN+F   P  R  K++ ++  GE  E++ E  + + 
Sbjct: 2093 DFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVI 2152

Query: 2102 LRAKCQGYVIFVISLGSTRKDDMEELASY 2130
            L+AKC+GY  F + LG  RK +++E+ ++
Sbjct: 2153 LQAKCKGY--FFVVLGIGRKVNIKEVYTF 2179



 Score =  299 bits (766), Expect = 2e-80
 Identities = 273/1049 (26%), Positives = 483/1049 (46%), Gaps = 90/1049 (8%)

Query: 21   SPGPGPVYADVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHS 80
            +P P     DVVFL+D S+ +    FP +K F+ +++ SL +  ++ RVA+ QYSD    
Sbjct: 413  APAPVSGEKDVVFLLDGSEGVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRP 471

Query: 81   EFHLSTFKGRSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRKQFPPILVV 140
            EF+L+++  +  ++N +++     G +   G AL+   R    +    R  +  P +L+V
Sbjct: 472  EFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIV 531

Query: 141  LASAESEDEVEEASKALQKDGVKIISVGVQKASEENLKAMA-TSHFHFNLRTIRDLSTFS 199
            L +  S D+V   S  +++ G   I +G+  A    ++ ++    F   + T R L T  
Sbjct: 532  LTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQ 591

Query: 200  QNMTQIIKDVTKYKEGAVDADMQVHFPI-SCQKDSLADLVFLVDESLGTGGNLRHLQTFL 258
            Q +++ +  +T+ +   +   +Q   P+ S       D+VFL+D S   G   ++++T +
Sbjct: 592  QVISERVTQLTREELSRLQPVLQ---PLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLI 648

Query: 259  ENITSSMDVKENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQIKNLSIQVGKS-NTGAA 317
            E +   +DV  +  R+ ++ +S+  K    L + +++ E Q  ++ L  + G+  N G A
Sbjct: 649  ERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNA 708

Query: 318  IDQMRRDGFSESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNLRLEDVNVFALSIQGAN 377
            ++ + R+ F    GSR  +GVPQ  VL++   SDDEV D A+ L+   V  F +    A 
Sbjct: 709  LEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI----AR 764

Query: 378  NTQLEEIV--SYPPEQTISTLKSYADLETYSTKFLKKLQNEIWSQISTYAEQRNLDKTGC 435
            N   EE+V  S  PE   S + ++ +L +   K L  +      QI              
Sbjct: 765  NADQEELVKISLSPEYVFS-VSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPP-A 822

Query: 436  VDTKEADIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFY 495
            V++  ADI FLID S  ++   F  I+ F+  +    +IGP KVRVGVVQ+S+D   EFY
Sbjct: 823  VESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFY 882

Query: 496  ITDYSNDIDLRKAIFNIKQLTGGT--YTGKALDYILQ--IIKNGMKDRMSKVPCYLIVLT 551
            +  Y +   +  AI  ++ L GG+   TGKAL+++ +   +K+        VP +L+++ 
Sbjct: 883  LKTYRSQAPVLDAIRRLR-LRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVL 941

Query: 552  DGMSTDRVVEPAKRLRAEQITVHAVGIGAANKIELQEIAGKEERVSFGQNFDALKSIKNE 611
             G S D V   A+ +R+  I    VG    ++ ELQ I      V   + F  L +I+  
Sbjct: 942  GGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEER 1001

Query: 612  VVREICAEKGC--------------EDMKADIMFLVDSSWSIGNENFRKMKIFMKNLLTK 657
            ++                       E  KADI+FL+D S +   ++F+++  F+  ++  
Sbjct: 1002 IMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDT 1061

Query: 658  IQIGADKTQIGVVQFSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTLTGKALNF-VG- 715
            +    D  Q+G+VQ++    +EF L  + T+++I DAI++  ++ +G   G+  N  VG 
Sbjct: 1062 VYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINK--VVYKG---GRHANTKVGL 1116

Query: 716  -----QYFTHSKGARLGAK--KFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANR 768
                  +F    G+RL  +  +   +IT G + +D +D +  L  + V +F+VGV N + 
Sbjct: 1117 EHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDS 1176

Query: 769  SQLEEISGDSSLVFHVENFDHLKALERKLIFRVCALHDCKRITL------------LDVV 816
             ++ +I+ +S+  F V N   L  L  +++     LHD    TL            LDV+
Sbjct: 1177 EEVGKIASNSATAFRVGNVQELSELSEQVLE---TLHDAMHETLCPGVTDAAKACNLDVI 1233

Query: 817  FVLDHSGS-----IKKQYQ---DHMIN--LTIHLVKKADVGRDRVQFGALKYSDQ-PNIL 865
               D S        +K ++   D ++N    +H V  +      V+   +  +   P   
Sbjct: 1234 LGFDGSRDQNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEA 1293

Query: 866  FYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKHANALFTEEHGSRIKQNVKQMLIVITD 925
            F  + Y  +  ++E  R  R       T   LK     F +     +K     ++I  TD
Sbjct: 1294 FDFDEY--QPEMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVK-----VVIHFTD 1346

Query: 926  GESHDHDQLNDTALELRNKGI-TIFAVGVGKANQKE----LE-GMAGNKNNTIYVDNFD- 978
            G   D   L+  +  LR +G+  +  VG+ +    E    LE G     +  + ++  D 
Sbjct: 1347 GADGDLADLHRASENLRQEGVRALILVGLERVVNLERLMHLEFGRGFMYDRPLRLNLLDL 1406

Query: 979  --KLKDVFTLVQERMCTEAPEVCHLQEAD 1005
              +L +    + E+ C   P  C  Q  D
Sbjct: 1407 DYELAEQLDNIAEKACCGVPCKCSGQRGD 1435



 Score =  270 bits (690), Expect = 1e-71
 Identities = 214/785 (27%), Positives = 391/785 (49%), Gaps = 41/785 (5%)

Query: 422  STYAEQRNLDKTGCVDTKEADIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRV 481
            +T+A+Q+       ++  + DI FL+DGSS++    F  I+ F+ +V +   IG D ++V
Sbjct: 22   TTHAQQQQ----AVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQV 77

Query: 482  GVVQYSDDTEVEFYITDYSNDIDLRKAIFNIKQLTGGT-YTGKALDYIL-QIIKNGMKDR 539
             V QY+D    EFY   +    ++  A+  +K L G   YTG ALD++   +  +    R
Sbjct: 78   AVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYR 137

Query: 540  MSK-VPCYLIVLTDGMSTDRVVEPAKRLRAEQITVHAVGIGAANKIELQEIAGKEERVSF 598
             ++ +P  L+++T G S D + +PA+ L+   I   A+G   A++ EL+EIA     V  
Sbjct: 138  AAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFI 197

Query: 599  GQNFDA--LKSIKNEVVREICAEKGC-EDMKADIMFLVDSSWSIGNENFRKMKIFMKNLL 655
               F A  L+ +   ++  +    G  E+ K DI+FL D S ++  + F  ++ F+  ++
Sbjct: 198  PAEFRAAPLQGMLPGLLAPLRTLSGTPEESKRDILFLFDGSANLVGQ-FPVVRDFLYKII 256

Query: 656  TKIQIGADKTQIGVVQFSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTLT-GKALNFV 714
             ++ +  + T+I V Q+SD  K E + + + ++ EI + + RM +     L  G AL++ 
Sbjct: 257  DELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYA 316

Query: 715  GQY-FTHSKGARL--GAKKFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANRSQL 771
             +Y F  S G+R+  G  +FL+L+  G + D V  PA  L+   V  F     NA+ ++L
Sbjct: 317  QRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAEL 376

Query: 772  EEISGDSSLVFHVENFDHLKALERKLIFRVCALHDCKRITL---LDVVFVLDHSGSIKKQ 828
            E+I    + +   E+   +  L  +++  + ++H+     +    DVVF+LD S  ++  
Sbjct: 377  EQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVRSG 436

Query: 829  YQDHMINLTIHLVKKADVGRDRVQFGALKYSDQPNILFYLNTYSNRSAIIENLRKRRDTG 888
            +   +      +V+  DVG+DRV+   ++YSD+    FYLN+Y N+  ++  +R+    G
Sbjct: 437  F-PLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLG 495

Query: 889  GNT-YTAKALKHA-NALFTEEHGSRIKQNVKQMLIVITDGESHDHDQLNDTALELRNKGI 946
            G T  T  AL+     +     GSRI + V Q+LIV+T   S   D + + ++ ++  G 
Sbjct: 496  GPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRS--GDDVRNPSVVVKRGGA 553

Query: 947  TIFAVGVGKANQKELEGMAGNKNNTIYVDNFDKLKDVFTLVQERMC-TEAPEVCHLQ--- 1002
                +G+G A+  E++ ++   +  + +  F +L  V  ++ ER+      E+  LQ   
Sbjct: 554  VPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVL 613

Query: 1003 ----------EADVIFLCDGSDRVSNSDFVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSN 1052
                      + DV+FL DGS + +  +F  + T +  L+D  D+     ++ + QF  +
Sbjct: 614  QPLPSPGVGGKRDVVFLIDGS-QSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDD 672

Query: 1053 YQSIIELKNSLTKTQWKTQIQNVSKSGGFP-RIDFALKKVS-NMFNLHAGGRRNAGVPQT 1110
             +    L    +K + +  +Q +   GG    +  AL+ VS N+F    G R   GVPQ 
Sbjct: 673  PKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQF 732

Query: 1111 LVVITSGDPRYDVADAVKTLKDLGICVLVLGIGDVYKEHLLPITGNSEKIITFQDFDKLK 1170
            LV+I+SG    +V D    LK  G+    +   +  +E L+ I+ + E + +   F +L 
Sbjct: 733  LVLISSGKSDDEVDDPAVELKQFGVAPFTIA-RNADQEELVKISLSPEYVFSVSTFRELP 791

Query: 1171 NVDVK 1175
            +++ K
Sbjct: 792  SLEQK 796



 Score =  101 bits (252), Expect = 8e-21
 Identities = 62/219 (28%), Positives = 110/219 (50%), Gaps = 1/219 (0%)

Query: 2290 MDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPN 2349
            +D+AF++D+++     +F E+K +I  ++    ++P P  S    RVAV+ ++P   + N
Sbjct: 2011 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2070

Query: 2350 TEECPVYLEFDLVTYNSIHQMKHHLQDSQ-QLNGDVFIGHALQWTIDNVFVGTPNLRKNK 2408
                PV +EF L  Y S  ++   L     QL G   +G A+++TI+NVF   PN R  K
Sbjct: 2071 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLK 2130

Query: 2409 VIFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHNDKELEELASHPLDHHLVQ 2468
            ++ ++  GE      +  + V L+AKC+GY   V   G K N KE+   AS P D     
Sbjct: 2131 IVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKL 2190

Query: 2469 LGRTHKPDWNYIIKFVKPFVHLIRRAINKYPTEDMKATC 2507
            + ++ + +   +++F +     +      Y + D++  C
Sbjct: 2191 VDKSTELNEEPLMRFGRLLPSFVSSENAFYLSPDIRKQC 2229



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 92/451 (20%), Positives = 180/451 (39%), Gaps = 57/451 (12%)

Query: 1758 ELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNSGTSYLIRWS 1817
            ++VF +D S  +   +FN  RD I  ++  L I ++      +VA+  Y         ++
Sbjct: 38   DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDL----IQVAVAQYADTVRPEFYFN 93

Query: 1818 DYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRT---YAGANVRRVAVFFSNG 1874
             +  K++++  + ++K  D +     G+A+ FV  N+F  +    A   + ++ V  + G
Sbjct: 94   THPTKREVITAVRKMKPLDGS-ALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGG 152

Query: 1875 QTASRSSIITATMEFSALDISPTVFAFDERVFLEAFGFDNTGTFQVIPVPPNGENQTLER 1934
            ++    S     ++ S++          ++  LE   FD++  F    +P       L+ 
Sbjct: 153  KSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVF----IPAEFRAAPLQG 208

Query: 1935 LRRCALCYDKCFPNACIREAFLPEDSYMDVVFLIDNSRNIAKDEFKAVKALVSSVIDNFN 1994
            +    L   +            PE+S  D++FL D S N+   +F  V+  +  +ID  N
Sbjct: 209  MLPGLLAPLRTLSGT-------PEESKRDILFLFDGSANLV-GQFPVVRDFLYKIIDELN 260

Query: 1995 IASDPLISDSGDRIALLSYSPWESSRRKMGTVKTEFDFITYDNQLLMKNHIQTSFQQLNG 2054
            +  +      G RIA+  YS           VK E  F  + ++  + N ++    +   
Sbjct: 261  VKPE------GTRIAVAQYS---------DDVKVESRFDEHQSKPEILNLVKRMKIKTGK 305

Query: 2055 EATIGRALLWTTENLFPETPYLRKH----KVIFVVSAGENYERKEFVKMMALRAKCQGYV 2110
               +G AL +    +F ++   R      + + ++ AG + +R   V   A   K  G V
Sbjct: 306  ALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDR---VDGPASNLKQSGVV 362

Query: 2111 IFVISLGSTRKDDMEELASYP----LDQHLIQLGRIHKPDLNYIAKFLKPFLYSVRRGFN 2166
             F+    +    ++E++   P      + L ++G +H   +N         L SV  G  
Sbjct: 363  PFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVN--------LLKSVHNG-- 412

Query: 2167 QYPPPMLEDACRLINLGGENIQNDGFQFVTE 2197
              P P+  +   +  L G      GF  + E
Sbjct: 413  -APAPVSGEKDVVFLLDGSEGVRSGFPLLKE 442



 Score = 38.1 bits (87), Expect = 0.11
 Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 17/116 (14%)

Query: 2291 DVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPNT 2350
            D+ FLID+S+ V  D F  ++ F++ ++   +I P+ +      RV V+ +S        
Sbjct: 829  DIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKV------RVGVVQFSN------- 875

Query: 2351 EECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGD-VFIGHALQWTIDNVFVGTPNLR 2405
                V+ EF L TY S   +   ++  +   G  +  G AL++   N+FV +   R
Sbjct: 876  ---DVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSR 928


>gi|240255540 alpha 3 type VI collagen isoform 3 precursor [Homo
            sapiens]
          Length = 1237

 Score =  393 bits (1009), Expect = e-108
 Identities = 318/1189 (26%), Positives = 571/1189 (48%), Gaps = 68/1189 (5%)

Query: 29   ADVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHSEFHLSTFK 88
            AD++FL+D S++ G  +F  +  F+  ++  LPI   + RV + Q+SDE  + F L T+ 
Sbjct: 35   ADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYS 94

Query: 89   GRSPMLNHLKKNFQFIGGSL-QIGKALQEAHRTYFSAPINGRDRKQFPPILVVLASAESE 147
             ++ +L  +K    F GG L  IG AL      +F+     R  +  P +LV++++  S 
Sbjct: 95   TKAQVLGAVKA-LGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSS 153

Query: 148  DEVEEASKALQKDGVKIISVGVQKASEENLKAMAT-SHFHFNLRTIRDLSTFSQNMTQII 206
            DE+     AL++  V    +G Q AS   L+ +AT  +  F +   R      + +   I
Sbjct: 154  DEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYI 213

Query: 207  KDVTKYKEGAVDADMQVHFPISCQKDSLADLVFLVDESLGTG-GNLRHLQTFLENITSSM 265
              V + +   +     V   I   K    D+VFLVD S   G  N   ++ F+  +   +
Sbjct: 214  VGVAQ-RHIVLKPPTIVTQVIEVNK---RDIVFLVDGSSALGLANFNAIRDFIAKVIQRL 269

Query: 266  DVKENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQIKNLSIQVGKS-NTGAAIDQMRRD 324
            ++ ++ +++ +  Y+++ +   +  +  T+ E    ++ +    G +  TG+A+D +R +
Sbjct: 270  EIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNN 329

Query: 325  GFSESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNLRLEDVNVFALSIQGANNTQLEEI 384
             F+ S G R A+G+P++ VL+T   S DE+   A  L+   +  FA+  +GA+  +LEEI
Sbjct: 330  LFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEI 389

Query: 385  VSYPPEQTISTLKSYADLETYSTKFLKKLQNEIWSQISTYAEQRNLDKTGCVDTKEADIH 444
                    I      A L+      L  L              R L  T  V + + DI 
Sbjct: 390  AFDSSLVFIPAEFRAAPLQGMLPGLLAPL--------------RTLSGTPEVHSNKRDII 435

Query: 445  FLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFYITDYSNDID 504
            FL+DGS+++ +  F  ++ F++ +     IG D +RVG+VQ+SD    EF +  Y    D
Sbjct: 436  FLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSD 495

Query: 505  LRKAIFNIKQLTGGT--YTGKALDYIL--QIIKNGMKDRMSKVPCYLIVLTDGMSTDRVV 560
            +   +  + QL GG+   TG AL Y+      + G       VP  L++LT G S D  +
Sbjct: 496  ILGHLRQL-QLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYL 554

Query: 561  EPAKRLRAEQITVHAVGIGAANKIELQEIAGKEERVSFGQNFDALKSIKNEVVREIC--A 618
            + A  L    I    VG   ANK EL++IA     V    +F +L ++  ++++ +    
Sbjct: 555  QAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYV 614

Query: 619  EKGCEDM-------KADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGADKTQIGVVQ 671
              G E++       K DI+FL D S ++  + F  ++ F+  ++ ++ +  + T+I V Q
Sbjct: 615  SGGVEEVPLAQPESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAVAQ 673

Query: 672  FSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTLT-GKALNFVGQY-FTHSKGARL--G 727
            +SD  K E + + + ++ EI + + RM +     L  G AL++  +Y F  S G+R+  G
Sbjct: 674  YSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDG 733

Query: 728  AKKFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGDSSLVFHVENF 787
              +FL+L+  G + D V  PA  L+   V  F     NA+ ++LE+I    + +   E+ 
Sbjct: 734  VLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESL 793

Query: 788  DHLKALERKLIFRVCALHDCKRITL---LDVVFVLDHSGSIKKQYQDHMINLTIHLVKKA 844
              +  L  +++  + ++H+     +    DVVF+LD S  ++  +   +      +V+  
Sbjct: 794  PKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVRSGF-PLLKEFVQRVVESL 852

Query: 845  DVGRDRVQFGALKYSDQPNILFYLNTYSNRSAIIENLRKRRDTGGNT-YTAKALKHA-NA 902
            DVG+DRV+   ++YSD+    FYLN+Y N+  ++  +R+    GG T  T  AL+     
Sbjct: 853  DVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRN 912

Query: 903  LFTEEHGSRIKQNVKQMLIVITDGESHDHDQLNDTALELRNKGITIFAVGVGKANQKELE 962
            +     GSRI + V Q+LIV+T   S   D + + ++ ++  G     +G+G A+  E++
Sbjct: 913  ILVSSAGSRITEGVPQLLIVLTADRS--GDDVRNPSVVVKRGGAVPIGIGIGNADITEMQ 970

Query: 963  GMAGNKNNTIYVDNFDKLKDVFTLVQERMC-TEAPEVCHLQ-------------EADVIF 1008
             ++   +  + +  F +L  V  ++ ER+      E+  LQ             + DV+F
Sbjct: 971  TISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVF 1030

Query: 1009 LCDGSDRVSNSDFVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSNYQSIIELKNSLTKTQW 1068
            L DGS + +  +F  + T +  L+D  D+     ++ + QF  + +    L    +K + 
Sbjct: 1031 LIDGS-QSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEV 1089

Query: 1069 KTQIQNVSKSGGFP-RIDFALKKVS-NMFNLHAGGRRNAGVPQTLVVITSGDPRYDVADA 1126
            +  +Q +   GG    +  AL+ VS N+F    G R   GVPQ LV+I+SG    +V D 
Sbjct: 1090 QNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDP 1149

Query: 1127 VKTLKDLGICVLVLGIGDVYKEHLLPITGNSEKIITFQDFDKLKNVDVK 1175
               LK  G+    +   +  +E L+ I+ + E + +   F +L +++ K
Sbjct: 1150 AVELKQFGVAPFTIA-RNADQEELVKISLSPEYVFSVSTFRELPSLEQK 1197



 Score =  328 bits (842), Expect = 3e-89
 Identities = 251/805 (31%), Positives = 407/805 (50%), Gaps = 62/805 (7%)

Query: 30   DVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHSEFHLSTFKG 89
            D++FL+D S ++G  +FP+V+ F+  ++NSL I  +  RV L Q+SD   +EF L+T++ 
Sbjct: 433  DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQT 492

Query: 90   RSPMLNHLKKNFQFIGGS-LQIGKALQEAHRTYFSAPINGRDRKQFPPILVVLASAESED 148
            +S +L HL++  Q  GGS L  G AL   +  +F+     R R+  P +L++L + +SED
Sbjct: 493  KSDILGHLRQ-LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSED 551

Query: 149  EVEEASKALQKDGVKIISVGVQKASEENLKAMATSHFHFN---LRTIRDLSTFSQNMTQI 205
               +A+ AL + G+    VG  +A++  L+ +A     FN   +  + D S+      Q+
Sbjct: 552  SYLQAANALTRAGILTFCVGASQANKAELEQIA-----FNPSLVYLMDDFSSLPALPQQL 606

Query: 206  IKDVTKYKEGAVDADMQVHFPISCQKDSLADLVFLVDESLGTGGNLRHLQTFLENITSSM 265
            I+ +T Y  G V+       P++ Q +S  D++FL D S    G    ++ FL  I   +
Sbjct: 607  IQPLTTYVSGGVE-----EVPLA-QPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDEL 660

Query: 266  DVKENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQIKNLSIQVGKS-NTGAAIDQMRRD 324
            +VK    R+ +  YS+  K  S      ++ E    +K + I+ GK+ N G A+D  +R 
Sbjct: 661  NVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRY 720

Query: 325  GFSESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNLRLEDVNVFALSIQGANNTQLEEI 384
             F +S GSR   GV Q  VL+    S D V   A NL+   V  F    + A+  +LE+I
Sbjct: 721  IFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQI 780

Query: 385  VSYPP-EQTISTLKSYADLETYSTKFLKKLQNEIWSQISTYAEQRNLDKTGCVDTKEADI 443
            V  P       +L    DL       LK + N   + +S                 E D+
Sbjct: 781  VLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVS----------------GEKDV 824

Query: 444  HFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFYITDYSNDI 503
             FL+DGS  ++   F  +K F+  V E   +G D+VRV VVQYSD T  EFY+  Y N  
Sbjct: 825  VFLLDGSEGVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQ 883

Query: 504  DLRKAIFNIKQLTGGT-YTGKALDYILQ-IIKNGMKDRMSK-VPCYLIVLTDGMSTDRVV 560
            D+  A+  +  L G T  TG AL+++L+ I+ +    R+++ VP  LIVLT   S D V 
Sbjct: 884  DVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVR 943

Query: 561  EPAKRLRAEQITVHAVGIGAANKIELQEIAGKEERVSFGQNFDALKSIKNEVVREICAEK 620
             P+  ++        +GIG A+  E+Q I+   +       F  L +++ +V+ E   + 
Sbjct: 944  NPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQ-QVISERVTQL 1002

Query: 621  GCEDM-----------------KADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGAD 663
              E++                 K D++FL+D S S G E F+ ++  ++ L+  + +G D
Sbjct: 1003 TREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFD 1061

Query: 664  KTQIGVVQFSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTL-TGKALNFVGQ-YFTHS 721
             T++ V+QFSD  K EF LN + ++ E+ +A+ R+       +  G AL +V +  F   
Sbjct: 1062 TTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRP 1121

Query: 722  KGARL--GAKKFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGDSS 779
             G+R+  G  +FL+LI+ G + D+V DPA  L+   V  F++   NA++ +L +IS    
Sbjct: 1122 LGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSPE 1180

Query: 780  LVFHVENFDHLKALERKLIFRVCAL 804
             VF V  F  L +LE+KL+  +  L
Sbjct: 1181 YVFSVSTFRELPSLEQKLLTPITTL 1205



 Score =  157 bits (396), Expect = 2e-37
 Identities = 111/406 (27%), Positives = 202/406 (49%), Gaps = 14/406 (3%)

Query: 21   SPGPGPVYADVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHS 80
            +P P     DVVFL+D S+ +    FP +K F+ +++ SL +  ++ RVA+ QYSD    
Sbjct: 814  APAPVSGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRP 872

Query: 81   EFHLSTFKGRSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRKQFPPILVV 140
            EF+L+++  +  ++N +++     G +   G AL+   R    +    R  +  P +L+V
Sbjct: 873  EFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIV 932

Query: 141  LASAESEDEVEEASKALQKDGVKIISVGVQKASEENLKAMA-TSHFHFNLRTIRDLSTFS 199
            L +  S D+V   S  +++ G   I +G+  A    ++ ++    F   + T R L T  
Sbjct: 933  LTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQ 992

Query: 200  QNMTQIIKDVTKYKEGAVDADMQVHFPI-SCQKDSLADLVFLVDESLGTGGNLRHLQTFL 258
            Q +++ +  +T+ +   +   +Q   P+ S       D+VFL+D S   G   ++++T +
Sbjct: 993  QVISERVTQLTREELSRLQPVLQ---PLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLI 1049

Query: 259  ENITSSMDVKENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQIKNLSIQVGKS-NTGAA 317
            E +   +DV  +  R+ ++ +S+  K    L + +++ E Q  ++ L  + G+  N G A
Sbjct: 1050 ERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNA 1109

Query: 318  IDQMRRDGFSESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNLRLEDVNVFALSIQGAN 377
            ++ + R+ F    GSR  +GVPQ  VL++   SDDEV D A+ L+   V  F +    A 
Sbjct: 1110 LEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI----AR 1165

Query: 378  NTQLEEIV--SYPPEQTISTLKSYADLETYSTKFLKKLQNEIWSQI 421
            N   EE+V  S  PE   S + ++ +L +   K L  +      QI
Sbjct: 1166 NADQEELVKISLSPEYVFS-VSTFRELPSLEQKLLTPITTLTSEQI 1210



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 78/381 (20%), Positives = 161/381 (42%), Gaps = 39/381 (10%)

Query: 1758 ELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNSGTSYLIRWS 1817
            ++VF +D S  +   +FN  RD I  ++  L I ++      +VA+  Y         ++
Sbjct: 239  DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLI----QVAVAQYADTVRPEFYFN 294

Query: 1818 DYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTY---AGANVRRVAVFFSNG 1874
             +  K++++  + ++K  D +     G+A+ FV  N+F  +    A   + ++ V  + G
Sbjct: 295  THPTKREVITAVRKMKPLDGSALY-TGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGG 353

Query: 1875 QTASRSSIITATMEFSALDISPTVFAFDERVFLEAFGFDNTGTFQVIPVPPNGENQTLER 1934
            ++    S     ++ S++          ++  LE   FD++  F    +P       L+ 
Sbjct: 354  KSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVF----IPAEFRAAPLQG 409

Query: 1935 LRRCALCYDKCFPNACIREAFLPEDSYMDVVFLIDNSRNIAKDEFKAVKALVSSVIDNFN 1994
            +    L      P   +        +  D++FL+D S N+ K  F  V+  V +++++ +
Sbjct: 410  MLPGLLA-----PLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD 464

Query: 1995 IASDPLISDSGDRIALLSYSPWESSRRKMGTVKTEFDFITYDNQLLMKNHIQTSFQQLNG 2054
            I +D +      R+ L+ +S          T  TEF   TY  +  +  H++    Q   
Sbjct: 465  IGNDNI------RVGLVQFS---------DTPVTEFSLNTYQTKSDILGHLRQLQLQGGS 509

Query: 2055 EATIGRALLWTTENLFPET--PYLRKH--KVIFVVSAGENYERKEFVKMMALRAKCQGYV 2110
                G AL +   N F E     +R+H  +++ +++AG++ +          RA   G +
Sbjct: 510  GLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRA---GIL 566

Query: 2111 IFVISLGSTRKDDMEELASYP 2131
             F +      K ++E++A  P
Sbjct: 567  TFCVGASQANKAELEQIAFNP 587



 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 57/266 (21%), Positives = 115/266 (43%), Gaps = 28/266 (10%)

Query: 1753 PAYPTELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNSGTSY 1812
            P    +++F  D S ++  + F   RD +  I+++LN++    P G R+A+  Y+     
Sbjct: 626  PESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVK----PEGTRIAVAQYSDDVKV 680

Query: 1813 LIRWSDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYAGANVRRVAVFFS 1872
              R+ ++  K ++L  + ++K + T +  ++G A+ +  R +F ++ AG+ +    + F 
Sbjct: 681  ESRFDEHQSKPEILNLVKRMKIK-TGKALNLGYALDYAQRYIFVKS-AGSRIEDGVLQFL 738

Query: 1873 NGQTASRSS--IITATMEFSALDISPTVFAFDERVFLEAFGFDNTGTFQVIPVPPNGENQ 1930
                A RSS  +           + P +F        +A   D     Q++  P      
Sbjct: 739  VLLVAGRSSDRVDGPASNLKQSGVVPFIF--------QAKNADPAELEQIVLSP--AFIL 788

Query: 1931 TLERLRRCALCYDKC--FPNACIREAFLPEDSYMDVVFLIDNSRNIAKDEFKAVKALVSS 1988
              E L +    + +      +    A  P     DVVFL+D S  + +  F  +K  V  
Sbjct: 789  AAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGV-RSGFPLLKEFVQR 847

Query: 1989 VIDNFNIASDPLISDSGDRIALLSYS 2014
            V+++ ++  D +      R+A++ YS
Sbjct: 848  VVESLDVGQDRV------RVAVVQYS 867



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 32/146 (21%), Positives = 68/146 (46%), Gaps = 11/146 (7%)

Query: 1758 ELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNSGTSYLIRWS 1817
            ++VF +D S     E F   R +I  +V+ L++  +      RVA++ ++         +
Sbjct: 1027 DVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDT----TRVAVIQFSDDPKVEFLLN 1081

Query: 1818 DYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYAG---ANVRRVAVFFSNG 1874
             ++ K ++   + +++ +   +  +VGNA+ +V+RN+FKR         V +  V  S+G
Sbjct: 1082 AHSSKDEVQNAVQRLRPKGGRQI-NVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSG 1140

Query: 1875 QTASRSSIITATMEFSALDISPTVFA 1900
            +  S   +    +E     ++P   A
Sbjct: 1141 K--SDDEVDDPAVELKQFGVAPFTIA 1164


>gi|240255542 alpha 3 type VI collagen isoform 2 precursor [Homo
           sapiens]
          Length = 1036

 Score =  332 bits (851), Expect = 3e-90
 Identities = 261/988 (26%), Positives = 484/988 (48%), Gaps = 72/988 (7%)

Query: 30  DVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHSEFHLSTFKG 89
           D+VFLVD S  LG  +F  ++ FI K+I  L I  +  +VA+AQY+D    EF+ +T   
Sbjct: 38  DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 97

Query: 90  RSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRKQFPPILVVLASAESEDE 149
           +  ++  ++K     G +L  G AL       F++    R  +  P +LV++   +S DE
Sbjct: 98  KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDE 157

Query: 150 VEEASKALQKDGVKIISVGVQKASEENLKAMATSHFHFNLRTIRDLSTFSQNMTQIIKDV 209
           + + ++ L++  +   ++G + A +  L+ +A     F+   +   + F     Q +   
Sbjct: 158 ISQPAQELKRSSIMAFAIGNKGADQAELEEIA-----FDSSLVFIPAEFRAAPLQGMLPG 212

Query: 210 TKYKEGAVDADMQVHFPISCQKDSLADLVFLVDESLGTG-GNLRHLQTFLENITSSMDVK 268
                  +    +VH        +  D++FL+D S   G  N  +++ F+ N+ +S+D+ 
Sbjct: 213 LLAPLRTLSGTPEVH-------SNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIG 265

Query: 269 ENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQIKNLSIQVGKS-NTGAAIDQMRRDGFS 327
            + +R+GL+ +S++  T   L +  T+S+    ++ L +Q G   NTG+A+  +  + F+
Sbjct: 266 NDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFT 325

Query: 328 ESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNLRLEDVNVFALSIQGANNTQLEEIVSY 387
           E+ GSR  + VPQ+ +L+T   S+D    AA  L    +  F +    AN  +LE+I   
Sbjct: 326 EAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFN 385

Query: 388 PPEQTISTLKSYADLETYSTKFLKKLQNEIWSQISTYAEQRNLDKTGCVDTKEADIHFLI 447
           P    +        ++ +S+  L  L  ++   ++TY      +        + DI FL 
Sbjct: 386 PSLVYL--------MDDFSS--LPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLF 435

Query: 448 DGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFYITDYSNDIDLRK 507
           DGS+++   QF  ++ F+ ++ +  ++ P+  R+ V QYSDD +VE    ++ +  ++  
Sbjct: 436 DGSANL-VGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILN 494

Query: 508 AIFNIKQLTGGTYT-GKALDYILQ--IIKNGMKDRMSKVPCYLIVLTDGMSTDRVVEPAK 564
            +  +K  TG     G ALDY  +   +K+        V  +L++L  G S+DRV  PA 
Sbjct: 495 LVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPAS 554

Query: 565 RLRAEQITVHAVGIGAANKIELQEIA-------GKEERVSFG----QNFDALKSIKNEVV 613
            L+   +         A+  EL++I          E     G    Q  + LKS+ N   
Sbjct: 555 NLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAP 614

Query: 614 REICAEKGCEDMKADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGADKTQIGVVQFS 673
             +  EK       D++FL+D S  +    F  +K F++ ++  + +G D+ ++ VVQ+S
Sbjct: 615 APVSGEK-------DVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYS 666

Query: 674 DKTKEEFQLNRYFTQQEISDAIDRMSLINEGT-LTGKALNFV-GQYFTHSKGARL--GAK 729
           D+T+ EF LN Y  +Q++ +A+ +++L+   T  TG AL FV       S G+R+  G  
Sbjct: 667 DRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVP 726

Query: 730 KFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGDSSLVFHVENFDH 789
           + LI++T   + DDVR+P+ +++        +G+ NA+ ++++ IS        +  F  
Sbjct: 727 QLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQ 786

Query: 790 LKALERKLIFRVCAL--HDCKRITLL-------------DVVFVLDHSGSIKKQYQDHMI 834
           L  +++ +  RV  L   +  R+  +             DVVF++D S S   ++Q ++ 
Sbjct: 787 LGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQ-YVR 845

Query: 835 NLTIHLVKKADVGRDRVQFGALKYSDQPNILFYLNTYSNRSAIIENLRKRRDTGGNTY-T 893
            L   LV   DVG D  +   +++SD P + F LN +S++  +   +++ R  GG     
Sbjct: 846 TLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINV 905

Query: 894 AKALKHANA-LFTEEHGSRIKQNVKQMLIVITDGESHDHDQLNDTALELRNKGITIFAVG 952
             AL++ +  +F    GSRI++ V Q L++I+ G+S   D+++D A+EL+  G+  F + 
Sbjct: 906 GNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKS--DDEVDDPAVELKQFGVAPFTI- 962

Query: 953 VGKANQKELEGMAGNKNNTIYVDNFDKL 980
              A+Q+EL  ++ +      V  F +L
Sbjct: 963 ARNADQEELVKISLSPEYVFSVSTFREL 990



 Score =  328 bits (842), Expect = 3e-89
 Identities = 251/805 (31%), Positives = 407/805 (50%), Gaps = 62/805 (7%)

Query: 30   DVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHSEFHLSTFKG 89
            D++FL+D S ++G  +FP+V+ F+  ++NSL I  +  RV L Q+SD   +EF L+T++ 
Sbjct: 232  DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQT 291

Query: 90   RSPMLNHLKKNFQFIGGS-LQIGKALQEAHRTYFSAPINGRDRKQFPPILVVLASAESED 148
            +S +L HL++  Q  GGS L  G AL   +  +F+     R R+  P +L++L + +SED
Sbjct: 292  KSDILGHLRQ-LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSED 350

Query: 149  EVEEASKALQKDGVKIISVGVQKASEENLKAMATSHFHFN---LRTIRDLSTFSQNMTQI 205
               +A+ AL + G+    VG  +A++  L+ +A     FN   +  + D S+      Q+
Sbjct: 351  SYLQAANALTRAGILTFCVGASQANKAELEQIA-----FNPSLVYLMDDFSSLPALPQQL 405

Query: 206  IKDVTKYKEGAVDADMQVHFPISCQKDSLADLVFLVDESLGTGGNLRHLQTFLENITSSM 265
            I+ +T Y  G V+       P++ Q +S  D++FL D S    G    ++ FL  I   +
Sbjct: 406  IQPLTTYVSGGVE-----EVPLA-QPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDEL 459

Query: 266  DVKENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQIKNLSIQVGKS-NTGAAIDQMRRD 324
            +VK    R+ +  YS+  K  S      ++ E    +K + I+ GK+ N G A+D  +R 
Sbjct: 460  NVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRY 519

Query: 325  GFSESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNLRLEDVNVFALSIQGANNTQLEEI 384
             F +S GSR   GV Q  VL+    S D V   A NL+   V  F    + A+  +LE+I
Sbjct: 520  IFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQI 579

Query: 385  VSYPP-EQTISTLKSYADLETYSTKFLKKLQNEIWSQISTYAEQRNLDKTGCVDTKEADI 443
            V  P       +L    DL       LK + N   + +S                 E D+
Sbjct: 580  VLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVS----------------GEKDV 623

Query: 444  HFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFYITDYSNDI 503
             FL+DGS  ++   F  +K F+  V E   +G D+VRV VVQYSD T  EFY+  Y N  
Sbjct: 624  VFLLDGSEGVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQ 682

Query: 504  DLRKAIFNIKQLTGGT-YTGKALDYILQ-IIKNGMKDRMSK-VPCYLIVLTDGMSTDRVV 560
            D+  A+  +  L G T  TG AL+++L+ I+ +    R+++ VP  LIVLT   S D V 
Sbjct: 683  DVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVR 742

Query: 561  EPAKRLRAEQITVHAVGIGAANKIELQEIAGKEERVSFGQNFDALKSIKNEVVREICAEK 620
             P+  ++        +GIG A+  E+Q I+   +       F  L +++ +V+ E   + 
Sbjct: 743  NPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQ-QVISERVTQL 801

Query: 621  GCEDM-----------------KADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGAD 663
              E++                 K D++FL+D S S G E F+ ++  ++ L+  + +G D
Sbjct: 802  TREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFD 860

Query: 664  KTQIGVVQFSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTL-TGKALNFVGQ-YFTHS 721
             T++ V+QFSD  K EF LN + ++ E+ +A+ R+       +  G AL +V +  F   
Sbjct: 861  TTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRP 920

Query: 722  KGARL--GAKKFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGDSS 779
             G+R+  G  +FL+LI+ G + D+V DPA  L+   V  F++   NA++ +L +IS    
Sbjct: 921  LGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSPE 979

Query: 780  LVFHVENFDHLKALERKLIFRVCAL 804
             VF V  F  L +LE+KL+  +  L
Sbjct: 980  YVFSVSTFRELPSLEQKLLTPITTL 1004



 Score =  326 bits (836), Expect = 2e-88
 Identities = 262/980 (26%), Positives = 475/980 (48%), Gaps = 61/980 (6%)

Query: 236  DLVFLVDESLGTG-GNLRHLQTFLENITSSMDVKENCMRLGLMSYSNSAKTISFLKSSTT 294
            D+VFLVD S   G  N   ++ F+  +   +++ ++ +++ +  Y+++ +   +  +  T
Sbjct: 38   DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 97

Query: 295  QSEFQQQIKNLSIQVGKS-NTGAAIDQMRRDGFSESYGSRRAQGVPQIAVLVTHRPSDDE 353
            + E    ++ +    G +  TG+A+D +R + F+ S G R A+G+P++ VL+T   S DE
Sbjct: 98   KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDE 157

Query: 354  VHDAALNLRLEDVNVFALSIQGANNTQLEEIVSYPPEQTISTLKSYADLETYSTKFLKKL 413
            +   A  L+   +  FA+  +GA+  +LEEI        I      A L+      L  L
Sbjct: 158  ISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPL 217

Query: 414  QNEIWSQISTYAEQRNLDKTGCVDTKEADIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFS 473
                          R L  T  V + + DI FL+DGS+++ +  F  ++ F++ +     
Sbjct: 218  --------------RTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD 263

Query: 474  IGPDKVRVGVVQYSDDTEVEFYITDYSNDIDLRKAIFNIKQLTGGT--YTGKALDYIL-- 529
            IG D +RVG+VQ+SD    EF +  Y    D+   +  + QL GG+   TG AL Y+   
Sbjct: 264  IGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQL-QLQGGSGLNTGSALSYVYAN 322

Query: 530  QIIKNGMKDRMSKVPCYLIVLTDGMSTDRVVEPAKRLRAEQITVHAVGIGAANKIELQEI 589
               + G       VP  L++LT G S D  ++ A  L    I    VG   ANK EL++I
Sbjct: 323  HFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQI 382

Query: 590  AGKEERVSFGQNFDALKSIKNEVVREIC--AEKGCEDM-------KADIMFLVDSSWSIG 640
            A     V    +F +L ++  ++++ +      G E++       K DI+FL D S ++ 
Sbjct: 383  AFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANLV 442

Query: 641  NENFRKMKIFMKNLLTKIQIGADKTQIGVVQFSDKTKEEFQLNRYFTQQEISDAIDRMSL 700
             + F  ++ F+  ++ ++ +  + T+I V Q+SD  K E + + + ++ EI + + RM +
Sbjct: 443  GQ-FPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKI 501

Query: 701  INEGTLT-GKALNFVGQY-FTHSKGARL--GAKKFLILITDGVAQDDVRDPARILRGKDV 756
                 L  G AL++  +Y F  S G+R+  G  +FL+L+  G + D V  PA  L+   V
Sbjct: 502  KTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGV 561

Query: 757  TIFSVGVYNANRSQLEEISGDSSLVFHVENFDHLKALERKLIFRVCALHDCKRITL---L 813
              F     NA+ ++LE+I    + +   E+   +  L  +++  + ++H+     +    
Sbjct: 562  VPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEK 621

Query: 814  DVVFVLDHSGSIKKQYQDHMINLTIHLVKKADVGRDRVQFGALKYSDQPNILFYLNTYSN 873
            DVVF+LD S  ++  +   +      +V+  DVG+DRV+   ++YSD+    FYLN+Y N
Sbjct: 622  DVVFLLDGSEGVRSGF-PLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMN 680

Query: 874  RSAIIENLRKRRDTGGNT-YTAKALKHA-NALFTEEHGSRIKQNVKQMLIVITDGESHDH 931
            +  ++  +R+    GG T  T  AL+     +     GSRI + V Q+LIV+T   S   
Sbjct: 681  KQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRS--G 738

Query: 932  DQLNDTALELRNKGITIFAVGVGKANQKELEGMAGNKNNTIYVDNFDKLKDVFTLVQERM 991
            D + + ++ ++  G     +G+G A+  E++ ++   +  + +  F +L  V  ++ ER+
Sbjct: 739  DDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERV 798

Query: 992  C-TEAPEVCHLQ-------------EADVIFLCDGSDRVSNSDFVTMTTFLSDLIDNFDI 1037
                  E+  LQ             + DV+FL DGS + +  +F  + T +  L+D  D+
Sbjct: 799  TQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGS-QSAGPEFQYVRTLIERLVDYLDV 857

Query: 1038 QSQRMKIGMAQFGSNYQSIIELKNSLTKTQWKTQIQNVSKSGGFP-RIDFALKKVS-NMF 1095
                 ++ + QF  + +    L    +K + +  +Q +   GG    +  AL+ VS N+F
Sbjct: 858  GFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIF 917

Query: 1096 NLHAGGRRNAGVPQTLVVITSGDPRYDVADAVKTLKDLGICVLVLGIGDVYKEHLLPITG 1155
                G R   GVPQ LV+I+SG    +V D    LK  G+    +   +  +E L+ I+ 
Sbjct: 918  KRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIA-RNADQEELVKISL 976

Query: 1156 NSEKIITFQDFDKLKNVDVK 1175
            + E + +   F +L +++ K
Sbjct: 977  SPEYVFSVSTFRELPSLEQK 996



 Score =  263 bits (673), Expect = 1e-69
 Identities = 210/755 (27%), Positives = 375/755 (49%), Gaps = 46/755 (6%)

Query: 422  STYAEQRNLDKTGCVDTKEADIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRV 481
            +T+A+Q+       ++  + DI FL+DGSS++    F  I+ F+ +V +   IG D ++V
Sbjct: 22   TTHAQQQQ----AVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQV 77

Query: 482  GVVQYSDDTEVEFYITDYSNDIDLRKAIFNIKQLTGGT-YTGKALDYILQ-IIKNGMKDR 539
             V QY+D    EFY   +    ++  A+  +K L G   YTG ALD++   +  +    R
Sbjct: 78   AVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYR 137

Query: 540  MSK-VPCYLIVLTDGMSTDRVVEPAKRLRAEQITVHAVGIGAANKIELQEIAGKEERVSF 598
             ++ +P  L+++T G S D + +PA+ L+   I   A+G   A++ EL+EIA     V  
Sbjct: 138  AAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFI 197

Query: 599  GQNFDA--LKSIKNEVVREICAEKGCEDM---KADIMFLVDSSWSIGNENFRKMKIFMKN 653
               F A  L+ +   ++  +    G  ++   K DI+FL+D S ++G  NF  ++ F+ N
Sbjct: 198  PAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMN 257

Query: 654  LLTKIQIGADKTQIGVVQFSDKTKEEFQLNRYFTQQEISDAIDRMSLI-NEGTLTGKALN 712
            L+  + IG D  ++G+VQFSD    EF LN Y T+ +I   + ++ L    G  TG AL+
Sbjct: 258  LVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALS 317

Query: 713  FV-GQYFTHSKGARL--GAKKFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANRS 769
            +V   +FT + G+R+     + L+L+T G ++D     A  L    +  F VG   AN++
Sbjct: 318  YVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKA 377

Query: 770  QLEEISGDSSLVFHVENFDHLKALERKLIFRV------------CALHDCKRITLLDVVF 817
            +LE+I+ + SLV+ +++F  L AL ++LI  +             A  + KR    D++F
Sbjct: 378  ELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKR----DILF 433

Query: 818  VLDHSGSIKKQYQDHMINLTIHLVKKADVGRDRVQFGALKYSDQPNILFYLNTYSNRSAI 877
            + D S ++  Q+   + +    ++ + +V  +  +    +YSD   +    + + ++  I
Sbjct: 434  LFDGSANLVGQF-PVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEI 492

Query: 878  IENLRKRR--DTGGNTYTAKALKHANA-LFTEEHGSRIKQNVKQMLIVITDGESHDHDQL 934
            + NL KR    TG       AL +A   +F +  GSRI+  V Q L+++  G S   D++
Sbjct: 493  L-NLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRS--SDRV 549

Query: 935  NDTALELRNKGITIFAVGVGKANQKELEGMAGNKNNTIYVDNFDKLKDVFTLV---QERM 991
            +  A  L+  G+  F      A+  ELE +  +    +  ++  K+ D+   +    + +
Sbjct: 550  DGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSV 609

Query: 992  CTEAPEVCHLQEADVIFLCDGSDRVSNSDFVTMTTFLSDLIDNFDIQSQRMKIGMAQFGS 1051
               AP      E DV+FL DGS+ V  S F  +  F+  ++++ D+   R+++ + Q+  
Sbjct: 610  HNGAPAPVS-GEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSD 667

Query: 1052 NYQSIIELKNSLTKTQWKTQIQNVSKSGG-FPRIDFALKKV-SNMFNLHAGGRRNAGVPQ 1109
              +    L + + K      ++ ++  GG  P    AL+ V  N+    AG R   GVPQ
Sbjct: 668  RTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQ 727

Query: 1110 TLVVITSGDPRYDVADAVKTLKDLGICVLVLGIGD 1144
             L+V+T+     DV +    +K  G   + +GIG+
Sbjct: 728  LLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGN 762



 Score =  157 bits (396), Expect = 2e-37
 Identities = 111/406 (27%), Positives = 202/406 (49%), Gaps = 14/406 (3%)

Query: 21   SPGPGPVYADVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHS 80
            +P P     DVVFL+D S+ +    FP +K F+ +++ SL +  ++ RVA+ QYSD    
Sbjct: 613  APAPVSGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRP 671

Query: 81   EFHLSTFKGRSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRKQFPPILVV 140
            EF+L+++  +  ++N +++     G +   G AL+   R    +    R  +  P +L+V
Sbjct: 672  EFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIV 731

Query: 141  LASAESEDEVEEASKALQKDGVKIISVGVQKASEENLKAMA-TSHFHFNLRTIRDLSTFS 199
            L +  S D+V   S  +++ G   I +G+  A    ++ ++    F   + T R L T  
Sbjct: 732  LTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQ 791

Query: 200  QNMTQIIKDVTKYKEGAVDADMQVHFPI-SCQKDSLADLVFLVDESLGTGGNLRHLQTFL 258
            Q +++ +  +T+ +   +   +Q   P+ S       D+VFL+D S   G   ++++T +
Sbjct: 792  QVISERVTQLTREELSRLQPVLQ---PLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLI 848

Query: 259  ENITSSMDVKENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQIKNLSIQVGKS-NTGAA 317
            E +   +DV  +  R+ ++ +S+  K    L + +++ E Q  ++ L  + G+  N G A
Sbjct: 849  ERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNA 908

Query: 318  IDQMRRDGFSESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNLRLEDVNVFALSIQGAN 377
            ++ + R+ F    GSR  +GVPQ  VL++   SDDEV D A+ L+   V  F +    A 
Sbjct: 909  LEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI----AR 964

Query: 378  NTQLEEIV--SYPPEQTISTLKSYADLETYSTKFLKKLQNEIWSQI 421
            N   EE+V  S  PE   S + ++ +L +   K L  +      QI
Sbjct: 965  NADQEELVKISLSPEYVFS-VSTFRELPSLEQKLLTPITTLTSEQI 1009



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 78/381 (20%), Positives = 161/381 (42%), Gaps = 39/381 (10%)

Query: 1758 ELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNSGTSYLIRWS 1817
            ++VF +D S  +   +FN  RD I  ++  L I ++      +VA+  Y         ++
Sbjct: 38   DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLI----QVAVAQYADTVRPEFYFN 93

Query: 1818 DYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTY---AGANVRRVAVFFSNG 1874
             +  K++++  + ++K  D +     G+A+ FV  N+F  +    A   + ++ V  + G
Sbjct: 94   THPTKREVITAVRKMKPLDGSALY-TGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGG 152

Query: 1875 QTASRSSIITATMEFSALDISPTVFAFDERVFLEAFGFDNTGTFQVIPVPPNGENQTLER 1934
            ++    S     ++ S++          ++  LE   FD++  F    +P       L+ 
Sbjct: 153  KSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVF----IPAEFRAAPLQG 208

Query: 1935 LRRCALCYDKCFPNACIREAFLPEDSYMDVVFLIDNSRNIAKDEFKAVKALVSSVIDNFN 1994
            +    L      P   +        +  D++FL+D S N+ K  F  V+  V +++++ +
Sbjct: 209  MLPGLLA-----PLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD 263

Query: 1995 IASDPLISDSGDRIALLSYSPWESSRRKMGTVKTEFDFITYDNQLLMKNHIQTSFQQLNG 2054
            I +D +      R+ L+ +S          T  TEF   TY  +  +  H++    Q   
Sbjct: 264  IGNDNI------RVGLVQFS---------DTPVTEFSLNTYQTKSDILGHLRQLQLQGGS 308

Query: 2055 EATIGRALLWTTENLFPET--PYLRKH--KVIFVVSAGENYERKEFVKMMALRAKCQGYV 2110
                G AL +   N F E     +R+H  +++ +++AG++ +          RA   G +
Sbjct: 309  GLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRA---GIL 365

Query: 2111 IFVISLGSTRKDDMEELASYP 2131
             F +      K ++E++A  P
Sbjct: 366  TFCVGASQANKAELEQIAFNP 386



 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 57/266 (21%), Positives = 115/266 (43%), Gaps = 28/266 (10%)

Query: 1753 PAYPTELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNSGTSY 1812
            P    +++F  D S ++  + F   RD +  I+++LN++    P G R+A+  Y+     
Sbjct: 425  PESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVK----PEGTRIAVAQYSDDVKV 479

Query: 1813 LIRWSDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYAGANVRRVAVFFS 1872
              R+ ++  K ++L  + ++K + T +  ++G A+ +  R +F ++ AG+ +    + F 
Sbjct: 480  ESRFDEHQSKPEILNLVKRMKIK-TGKALNLGYALDYAQRYIFVKS-AGSRIEDGVLQFL 537

Query: 1873 NGQTASRSS--IITATMEFSALDISPTVFAFDERVFLEAFGFDNTGTFQVIPVPPNGENQ 1930
                A RSS  +           + P +F        +A   D     Q++  P      
Sbjct: 538  VLLVAGRSSDRVDGPASNLKQSGVVPFIF--------QAKNADPAELEQIVLSP--AFIL 587

Query: 1931 TLERLRRCALCYDKC--FPNACIREAFLPEDSYMDVVFLIDNSRNIAKDEFKAVKALVSS 1988
              E L +    + +      +    A  P     DVVFL+D S  + +  F  +K  V  
Sbjct: 588  AAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGV-RSGFPLLKEFVQR 646

Query: 1989 VIDNFNIASDPLISDSGDRIALLSYS 2014
            V+++ ++  D +      R+A++ YS
Sbjct: 647  VVESLDVGQDRV------RVAVVQYS 666



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 32/146 (21%), Positives = 68/146 (46%), Gaps = 11/146 (7%)

Query: 1758 ELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNSGTSYLIRWS 1817
            ++VF +D S     E F   R +I  +V+ L++  +      RVA++ ++         +
Sbjct: 826  DVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDT----TRVAVIQFSDDPKVEFLLN 880

Query: 1818 DYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYAG---ANVRRVAVFFSNG 1874
             ++ K ++   + +++ +   +  +VGNA+ +V+RN+FKR         V +  V  S+G
Sbjct: 881  AHSSKDEVQNAVQRLRPKGGRQI-NVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSG 939

Query: 1875 QTASRSSIITATMEFSALDISPTVFA 1900
            +  S   +    +E     ++P   A
Sbjct: 940  K--SDDEVDDPAVELKQFGVAPFTIA 963


>gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Homo
            sapiens]
          Length = 1019

 Score =  310 bits (793), Expect = 2e-83
 Identities = 261/908 (28%), Positives = 402/908 (44%), Gaps = 97/908 (10%)

Query: 1295 KDKSASRGQVLLIFSDGLQSESNIM-LENQSDRLREAGLDALLVV-----------SLNT 1342
            +D+S       ++ +DG  + S    ++ Q++R RE G+    V             + +
Sbjct: 147  QDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERAREEGIRLFAVAPNQNLKEQGLRDIAS 206

Query: 1343 TAHHEFSSFEFGKRFDYRTHLTIGM---RELGKKLSQYLGNIAERTCCCTFC-KCPGIPG 1398
            T H  +       R DY T L       ++   ++ + + + A   C    C + PG  G
Sbjct: 207  TPHELY-------RNDYATMLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIPGPSG 259

Query: 1399 PHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFSG 1458
            P G RG +  KG+ G  G  G +G  G+PG+ G  G  G KG+ G  G  G+ G  G  G
Sbjct: 260  PKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKG 319

Query: 1459 PKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPG 1518
              G  G +G DG  G+ G  G PG KG+ G+ G  G PG  G+PG+ G++G  GDPG PG
Sbjct: 320  APGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPG 379

Query: 1519 QNN-----NIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPG 1573
            +         KG KG +G  G  G  G KG +G P  RG +G  G+RG  G  G PG+ G
Sbjct: 380  RRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDG 439

Query: 1574 PTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPG 1633
            P G  G  G +GP+G  G  G KG KG +G  GP+G  G +G  G         K+G  G
Sbjct: 440  PKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPG---------KQGSRG 490

Query: 1634 LPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGP 1693
             PGD GP G +GQ G +GD G PG+   G +G  G +G PG  G +G  G+ G+ G PG 
Sbjct: 491  DPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGR 550

Query: 1694 KGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCDLIRFLREHSPC--WKEK 1751
            KG +G     G  GE G RG  G PG  G  G  G P  ++CD++ ++RE   C   +++
Sbjct: 551  KGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKR 610

Query: 1752 CPAYPTELVFALDNSYDVTEESFNKTRDIITSIVNDLN--IRENNCPVGARVAMVSY-NS 1808
            C A   ++VF +D+S  +   +F   ++ + ++VN L    ++     G RV +V Y + 
Sbjct: 611  CGA--LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHE 668

Query: 1809 GTSYLIRWSD-----YNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYAGAN 1863
            GT   I+  D      +  K+ ++ L  I     T      +A++F    + K +     
Sbjct: 669  GTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTP-----SALKFAYDRLIKES-RRQK 722

Query: 1864 VRRVAVFFSNGQTASRSSIITATMEFSALDISPTVFAFDERVFLEAFGFDNTGTFQVIPV 1923
             R  AV  ++G+   R   +         D++ T     + +F E    +N  +      
Sbjct: 723  TRVFAVVITDGRHDPRDDDLN-LRALCDRDVTVTAIGIGD-MFHEKHESENLYSI-ACDK 779

Query: 1924 PPNGENQTL------ERL---RRCALCYDK---CFPNACIREAFLPEDSY--MDVVFLID 1969
            P    N TL      E+        LC D    C    C  E  + + +   +D+VFL+D
Sbjct: 780  PQQVRNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRPVDIVFLLD 839

Query: 1970 NSRNIAKDEFKAVKALVSSVIDNFNIA---SDPLISDSGDRIALLSYSPWESSRRKMGTV 2026
             S  + +  F   +  V  V     +A    DPL      R+ALL +          G  
Sbjct: 840  GSERLGEQNFHKARRFVEQVARRLTLARRDDDPL----NARVALLQFG---------GPG 886

Query: 2027 KTEFDFITYDNQLLMKNHIQTSFQQLNGEATIGRALLWTTENLFPETPY--LRKHKVIFV 2084
            + +  F    N   +   ++T+ Q LN  + +G  ++    N    +P    R+H  +  
Sbjct: 887  EQQVAFPLSHNLTAIHEALETT-QYLNSFSHVGAGVVHAI-NAIVRSPRGGARRHAELSF 944

Query: 2085 VSAGENYERKEFVKMMALRAKCQGYVIFVISLGSTRKDDMEELASYPLDQHLIQLGRIHK 2144
            V   +     + +   A   + Q  V  V++LGS    DM+ L +  L     +    H+
Sbjct: 945  VFLTDGVTGNDSLHESAHSMRKQNVVPTVLALGS--DVDMDVLTTLSLGD---RAAVFHE 999

Query: 2145 PDLNYIAK 2152
             D + +A+
Sbjct: 1000 KDYDSLAQ 1007



 Score = 89.0 bits (219), Expect = 5e-17
 Identities = 103/409 (25%), Positives = 180/409 (44%), Gaps = 58/409 (14%)

Query: 434  GCVDTKEA----DIHFLIDGSSSIQEKQFEQIKRFMLEVTEMF-SIGPDK-----VRVGV 483
            GC D ++     D+ F+ID S SI    F   K F++ V     +I  D       RVGV
Sbjct: 603  GCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGV 662

Query: 484  VQYSDDTEVEFYITDYSNDIDL---RKAIFNIKQLTGGTYTGKALDYIL-QIIKNGMKDR 539
            VQYS +   E    D      L   ++A+ N++ + GGT+T  AL +   ++IK   + R
Sbjct: 663  VQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIK---ESR 719

Query: 540  MSKVPCYLIVLTDGMSTDRVVEPAKRLRA---EQITVHAVGIGAA--NKIELQEI----A 590
              K   + +V+TDG    R  +    LRA     +TV A+GIG     K E + +     
Sbjct: 720  RQKTRVFAVVITDGRHDPR--DDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIAC 777

Query: 591  GKEERVSFGQNFDALKSIK--NEVVREICAEKG----------------CEDMKADIMFL 632
             K ++V     F  L + K  +++   +C +                  C     DI+FL
Sbjct: 778  DKPQQVRNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRPVDIVFL 837

Query: 633  VDSSWSIGNENFRKMKIFMKNLLTKIQIGAD-----KTQIGVVQFSDKTKEEFQLNRYFT 687
            +D S  +G +NF K + F++ +  ++ +          ++ ++QF    +++        
Sbjct: 838  LDGSERLGEQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQVAFPLSHN 897

Query: 688  QQEISDAIDRMSLINEGTLTGKALNFVGQYFTHSK--GARLGAKKFLILITDGV-AQDDV 744
               I +A++    +N  +  G  +         S   GAR  A+   + +TDGV   D +
Sbjct: 898  LTAIHEALETTQYLNSFSHVGAGVVHAINAIVRSPRGGARRHAELSFVFLTDGVTGNDSL 957

Query: 745  RDPARILRGKDV--TIFSVGVYNANRSQLEEIS-GDSSLVFHVENFDHL 790
             + A  +R ++V  T+ ++G  + +   L  +S GD + VFH +++D L
Sbjct: 958  HESAHSMRKQNVVPTVLALG-SDVDMDVLTTLSLGDRAAVFHEKDYDSL 1005



 Score = 77.8 bits (190), Expect = 1e-13
 Identities = 106/429 (24%), Positives = 182/429 (42%), Gaps = 58/429 (13%)

Query: 802  CALHDC-KRITLLDVVFVLDHSGSI-------KKQYQDHMINLTIHLVK--KADVGRDRV 851
            C   DC KR   LDVVFV+D S SI       +K +  +++N    + K  K++ G    
Sbjct: 602  CGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETG---T 658

Query: 852  QFGALKYSDQPN---ILFYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKHANALFTEEH 908
            + G ++YS +     I        + S+  E ++      G T+T  ALK A     +E 
Sbjct: 659  RVGVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKE- 717

Query: 909  GSRIKQNVKQMLIVITDGESHD--HDQLNDTALELRNKGITIFAVGVG-----KANQKEL 961
             SR +Q  +   +VITDG  HD   D LN  AL   ++ +T+ A+G+G     K   + L
Sbjct: 718  -SR-RQKTRVFAVVITDGR-HDPRDDDLNLRAL--CDRDVTVTAIGIGDMFHEKHESENL 772

Query: 962  EGMAGNK-----NNTIYVDN-----FDKLKDVFTLVQERMCTEAP-------EVCHLQEA 1004
              +A +K     N T++ D       D ++DV     + +C + P         C  +  
Sbjct: 773  YSIACDKPQQVRNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRPV 832

Query: 1005 DVIFLCDGSDRVSNSDFVTMTTFLSDL-----IDNFDIQSQRMKIGMAQFGSNYQSIIEL 1059
            D++FL DGS+R+   +F     F+  +     +   D      ++ + QFG   +  +  
Sbjct: 833  DIVFLLDGSERLGEQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQVAF 892

Query: 1060 KNSLTKTQWKTQIQNVSKSGGFPRIDFALKKVSNMF--NLHAGGRRNAGVPQTLVVITSG 1117
              S   T     ++       F  +   +    N    +   G RR+A +  + V +T G
Sbjct: 893  PLSHNLTAIHEALETTQYLNSFSHVGAGVVHAINAIVRSPRGGARRHAEL--SFVFLTDG 950

Query: 1118 DPRYD-VADAVKTLKDLGICVLVLGIG-DVYKEHLLPIT-GNSEKIITFQDFDKLKNVDV 1174
                D + ++  +++   +   VL +G DV  + L  ++ G+   +   +D+D L     
Sbjct: 951  VTGNDSLHESAHSMRKQNVVPTVLALGSDVDMDVLTTLSLGDRAAVFHEKDYDSLAQPGF 1010

Query: 1175 KKRIIREIC 1183
              R IR IC
Sbjct: 1011 FDRFIRWIC 1019



 Score = 65.9 bits (159), Expect = 5e-10
 Identities = 95/424 (22%), Positives = 179/424 (42%), Gaps = 46/424 (10%)

Query: 229  CQKDSLA-DLVFLVDESLGTG-GNLRHLQTFLENITSSMDV------KENCMRLGLMSYS 280
            C+K   A D+VF++D S   G  N    + F+ N+ + +         E   R+G++ YS
Sbjct: 607  CEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYS 666

Query: 281  NSAKTISFLKSSTTQ----SEFQQQIKNLSIQVGKSNTGAAIDQMRRDGFSESYGSRRAQ 336
            +   T   ++    +    S F++ +KNL    G + T +A+    +  +       R Q
Sbjct: 667  HEG-TFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSAL----KFAYDRLIKESRRQ 721

Query: 337  GVPQIAVLVT---HRPSDDEVHDAALNLRLEDVNVFALSI-----QGANNTQLEEIVSYP 388
                 AV++T   H P DD+++  AL  R  DV V A+ I     +   +  L  I    
Sbjct: 722  KTRVFAVVITDGRHDPRDDDLNLRALCDR--DVTVTAIGIGDMFHEKHESENLYSIACDK 779

Query: 389  PEQTISTLKSYADLETYSTKFLKKLQNEIWSQISTYAE----QRNLDKTGCVDTKEADIH 444
            P+Q +  +  ++DL   + KF+  +++ +             Q  L    C   +  DI 
Sbjct: 780  PQQ-VRNMTLFSDL--VAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQ-RPVDIV 835

Query: 445  FLIDGSSSIQEKQFEQIKRFMLEVTEMFSIG-----PDKVRVGVVQYSDDTEVEFYITDY 499
            FL+DGS  + E+ F + +RF+ +V    ++      P   RV ++Q+    E +      
Sbjct: 836  FLLDGSERLGEQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQVAFPLS 895

Query: 500  SNDIDLRKAIFNIKQLTGGTYTGKALDYILQ-IIKNGMKDRMSKVPCYLIVLTDGMS-TD 557
             N   + +A+   + L   ++ G  + + +  I+++             + LTDG++  D
Sbjct: 896  HNLTAIHEALETTQYLNSFSHVGAGVVHAINAIVRSPRGGARRHAELSFVFLTDGVTGND 955

Query: 558  RVVEPAKRLRAEQI--TVHAVGIGAANKIELQEIAGKEERVSFGQNFDAL--KSIKNEVV 613
             + E A  +R + +  TV A+G      +      G    V   +++D+L      +  +
Sbjct: 956  SLHESAHSMRKQNVVPTVLALGSDVDMDVLTTLSLGDRAAVFHEKDYDSLAQPGFFDRFI 1015

Query: 614  REIC 617
            R IC
Sbjct: 1016 RWIC 1019



 Score = 64.7 bits (156), Expect = 1e-09
 Identities = 95/393 (24%), Positives = 171/393 (43%), Gaps = 66/393 (16%)

Query: 613 VREICAEKGCEDM--KADIMFLVDSSWSIGNENFRKMKIFMKNLLTKI-QIGADK----- 664
           VRE C    CE      D++F++DSS SIG  NF   K F+ N++ ++  I  D      
Sbjct: 598 VRETCGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETG 657

Query: 665 TQIGVVQFS-DKTKEEFQLN--RYFTQQEISDAIDRMSLINEGTLTGKALNFVGQYFTHS 721
           T++GVVQ+S + T E  QL+  R  +     +A+  +  I  GT T  AL F        
Sbjct: 658 TRVGVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLI-K 716

Query: 722 KGARLGAKKFLILITDGVAQDDVRDP---ARILRGKDVTIFSVGVYNA------------ 766
           +  R   + F ++ITDG  + D RD     R L  +DVT+ ++G+ +             
Sbjct: 717 ESRRQKTRVFAVVITDG--RHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYS 774

Query: 767 ----NRSQLEEISGDSSLVFH--VENFDHLKALERKLIFRVCALHDCKRITL-------- 812
                  Q+  ++  S LV    +++ + +   + ++   VC    C+            
Sbjct: 775 IACDKPQQVRNMTLFSDLVAEKFIDDMEDVLCPDPQI---VCPDLPCQTELSVAQCTQRP 831

Query: 813 LDVVFVLDHSGSIKKQYQDHMINLTIHLVKKADVGR----------DRVQFGALKYSDQP 862
           +D+VF+LD S  + +Q           + ++  + R            +QFG      + 
Sbjct: 832 VDIVFLLDGSERLGEQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGG---PGEQ 888

Query: 863 NILFYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKHA-NALFTEEHGSRIKQNVKQMLI 921
            + F L+   N +AI E L   +     ++    + HA NA+     G   +++ +   +
Sbjct: 889 QVAFPLS--HNLTAIHEALETTQYLNSFSHVGAGVVHAINAIVRSPRGG-ARRHAELSFV 945

Query: 922 VITDGESHDHDQLNDTALELRNKGI--TIFAVG 952
            +TDG +  +D L+++A  +R + +  T+ A+G
Sbjct: 946 FLTDGVT-GNDSLHESAHSMRKQNVVPTVLALG 977



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 81/368 (22%), Positives = 149/368 (40%), Gaps = 44/368 (11%)

Query: 30  DVVFLVDSSDHLGPKSFPFVKTFINKMINSL------PIEANKYRVALAQYSDEFHSEFH 83
           DVVF++DSS+ +G  +F   K F+  ++N L      P      RV + QYS E   E  
Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFE-A 673

Query: 84  LSTFKGRSPMLNHLK---KNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRKQFPPILVV 140
           +     R   L+  K   KN ++I G      AL+ A    +   I    R++     VV
Sbjct: 674 IQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFA----YDRLIKESRRQKTRVFAVV 729

Query: 141 LASAESEDEVEEAS-KALQKDGVKIISVGV-----QKASEENLKAMATSHFHFNLRTIRD 194
           +     +   ++ + +AL    V + ++G+     +K   ENL ++A        + +R+
Sbjct: 730 ITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACD----KPQQVRN 785

Query: 195 LSTFSQNMTQ-IIKDVTKYKEGAVDADMQVHFP-ISCQKD-SLA-------DLVFLVDES 244
           ++ FS  + +  I D+    E  +  D Q+  P + CQ + S+A       D+VFL+D S
Sbjct: 786 MTLFSDLVAEKFIDDM----EDVLCPDPQIVCPDLPCQTELSVAQCTQRPVDIVFLLDGS 841

Query: 245 LGTG-GNLRHLQTFLENITSSMDVKEN-----CMRLGLMSYSNSAKTISFLKSSTTQSEF 298
              G  N    + F+E +   + +          R+ L+ +    +       S   +  
Sbjct: 842 ERLGEQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQVAFPLSHNLTAI 901

Query: 299 QQQIKNLSIQVGKSNTGAAIDQMRRDGFSESYGSRRAQGVPQIAVLVTHRPSDDEVHDAA 358
            + ++        S+ GA +            G  R         L      +D +H++A
Sbjct: 902 HEALETTQYLNSFSHVGAGVVHAINAIVRSPRGGARRHAELSFVFLTDGVTGNDSLHESA 961

Query: 359 LNLRLEDV 366
            ++R ++V
Sbjct: 962 HSMRKQNV 969



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 44/176 (25%), Positives = 78/176 (44%), Gaps = 13/176 (7%)

Query: 2290 MDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPN 2349
            +DV F+ID+S+ +G   F   K F+ +V++          S  G RV V+ YS  G    
Sbjct: 614  LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEG---- 669

Query: 2350 TEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLRKNKV 2409
            T E    ++ D    +S+   K  +++ + + G  +   AL++  D +   +   +    
Sbjct: 670  TFEA---IQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVF 726

Query: 2410 IFVISAGETNSLDKDVLRNVSLRAKC-QGYSIFVFSFGPKHNDK-ELEELASHPLD 2463
              VI+ G  +  D D    ++LRA C +  ++     G   ++K E E L S   D
Sbjct: 727  AVVITDGRHDPRDDD----LNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACD 778



 Score = 36.2 bits (82), Expect = 0.42
 Identities = 31/113 (27%), Positives = 52/113 (46%), Gaps = 12/113 (10%)

Query: 2290 MDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPN 2349
            +D+ FL+D S+R+G   F + + F+  V     +A       L  RVA+L +  PG    
Sbjct: 832  VDIVFLLDGSERLGEQNFHKARRFVEQVARRLTLARRD-DDPLNARVALLQFGGPG---- 886

Query: 2350 TEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTP 2402
             ++    L  +L    +IH+    L+ +Q LN    +G  +   I N  V +P
Sbjct: 887  EQQVAFPLSHNL---TAIHEA---LETTQYLNSFSHVGAGVVHAI-NAIVRSP 932


>gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]
          Length = 957

 Score =  305 bits (782), Expect = 3e-82
 Identities = 241/797 (30%), Positives = 362/797 (45%), Gaps = 79/797 (9%)

Query: 986  LVQERMCTEAPEV---CHLQEADVIFLCDGSDRVSNSDFVTMTTFLSDLIDNFDIQSQRM 1042
            L+Q  +  E  EV   C     D++F+ DGS  V   +F  +  +L ++  NFDI  + +
Sbjct: 15   LLQNSVLAEDGEVRSSCRTAPTDLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFI 74

Query: 1043 KIGMAQFGSNYQSIIELKNSLTKTQWKTQIQNVSKSGGFPRIDFALKKVSNMFNLHAGGR 1102
            ++G+ Q+       I L +  +       ++++   GG  +   A++   +    +   +
Sbjct: 75   QVGVVQYSDYPVLEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAIQFALD----YLFAK 130

Query: 1103 RNAGVPQTLVVITSGDPRYDVADAVKTLKDLGICVLVLGIGDVYKEHLLPITGN---SEK 1159
             +  + +  VV+T G  + DV DA +  +D  I +  +G+G   ++  L    N   S  
Sbjct: 131  SSRFLTKIAVVLTDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTY 190

Query: 1160 IITFQDF---DKLKNVDVKKRIIREICQS----CGKTNCFMDIVVGFDISTHVQGQPLFQ 1212
            +   +D+    K++ V  +K     +C +      +     DI++G D++  V+ +   Q
Sbjct: 191  VFYVEDYIAISKIREVMKQKLCEESVCPTRIPVAARDERGFDILLGLDVNKKVKKR--IQ 248

Query: 1213 GHPQ-LESYLPGILEDISSIKGVSCGAGTEAQVSLAFKVNSDQGFPAK--FQIYQKAVFD 1269
              P+ ++ Y      D+S +       G       ++   S Q F  K  + +++    D
Sbjct: 249  LSPKKIKGYEVTSKVDLSELTSNVFPEGLPP----SYVFVSTQRFKVKKIWDLWRILTID 304

Query: 1270 SLLQVNVS--GPTHLNAQFLRSLWDTFKDKSASRGQVLLIFSDG------LQSESNIMLE 1321
               Q+ V+  G   +      S+ +  +  + +  QV  +F +G      L +E ++ L 
Sbjct: 305  GRPQIAVTLNGVDKILLFTTTSVINGSQVVTFANPQVKTLFDEGWHQIRLLVTEQDVTLY 364

Query: 1322 NQSDRLREAGLDALLVVSLN-TTAHHEFSSFEFGKRFDYRTHLTIGMRELGKKLSQYLGN 1380
                ++    L  +L + +N  T   ++S  E   +FD +            KL  Y   
Sbjct: 365  IDDQQIENKPLHPVLGILINGQTQIGKYSGKEETVQFDVQ------------KLRIYCD- 411

Query: 1381 IAERTCCCTFCKCPGIPG------------------PHGTRGLQAMKGSQGLKGSRGHRG 1422
              E+    T C+ PG  G                  P G  GLQ  KG  GL G+ G+ G
Sbjct: 412  -PEQNNRETACEIPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPG 470

Query: 1423 EDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPG 1482
            + G  G  G  G  G  G+ G PG  G +GL G+ G  G  GD G  GL G  G HG PG
Sbjct: 471  QPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPG 530

Query: 1483 IKGE---KGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQ-----NNNIKGQKGSKGEQG 1534
             KGE   KGD GS G  G +GA G+ G  GFPG PG  G+      + + G  G KGE G
Sbjct: 531  SKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAG 590

Query: 1535 RQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPG 1594
              G  GQ G +G P   G  G  G RGL G  GE G PG  G  GA G+ G  GS G+PG
Sbjct: 591  SPGAPGQDGTRGEP---GIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPG 647

Query: 1595 RKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSG 1654
            + G  GS+G KG  G  G+ GA G  G PG  G  GEPG  G  G  G+ G +G QG+ G
Sbjct: 648  QPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKG 707

Query: 1655 IPGY-GQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRG 1713
            I G  G+ GR+G+ G +G  G  G KG+ G  G PG  G  G +G +   GL G  G +G
Sbjct: 708  IQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKG 767

Query: 1714 LPGPPGQRGIKGMAGQP 1730
             PG PG +G  G+ G+P
Sbjct: 768  QPGDPGPQGPPGLDGKP 784



 Score =  254 bits (650), Expect = 6e-67
 Identities = 158/407 (38%), Positives = 201/407 (49%), Gaps = 73/407 (17%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PG  G  G Q + G+ G+ GS G +G  G PG +G+ G  GDKG  G PG  G  G+
Sbjct: 469  PGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGM 528

Query: 1454 KGFSGPKGGHGDDGIDGL------DGEEGCHGFPGIKGEKGDPGS------------QGS 1495
             G  G  G  GD G  G        GE+G  GFPG+ G  G+PG             +G 
Sbjct: 529  PGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGE 588

Query: 1496 PGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGV----------- 1544
             GS GAPGQ G +G PG PG PG N  + GQKG  G  G+QG+ G  G+           
Sbjct: 589  AGSPGAPGQDGTRGEPGIPGFPG-NRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPG 647

Query: 1545 -QGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGT------LGAEGLQGPQGSQGNPGRKG 1597
              G+P S+GS+G  G +G+ G SG  G PG TG+      +G  G+QG +G +GN G KG
Sbjct: 648  QPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKG 707

Query: 1598 EKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG 1657
             +G +G+ G QG PG  G +G  G  G  G+KGEPG+ G +G  G++G  G  G +G   
Sbjct: 708  IQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAG--P 765

Query: 1658 YGQMGRKGVKGPRGFPGDAG------------------------QKGDI----------G 1683
             GQ G  G +GP G  G  G                        Q G I          G
Sbjct: 766  KGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHG 825

Query: 1684 NPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
            +PGIPG PGP G  G     GL G +G  GL G PG+ G++G+ G P
Sbjct: 826  SPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLP 872



 Score =  244 bits (623), Expect = 8e-64
 Identities = 150/376 (39%), Positives = 187/376 (49%), Gaps = 43/376 (11%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG+PGP G  G     G  GL GS G +GE G+PG  G  G +G+ GI G PG  G  G 
Sbjct: 562  PGLPGPAGEPGRH---GKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQ 618

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD 1513
            KG  GP G  G  G  G+ G  G +G PG  G  G  GS+G PG +G PG  G KG PG 
Sbjct: 619  KGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGA 678

Query: 1514 PGNPGQNN-----NIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGE 1568
             G+PG+        I+G+KG KG QG +G  GQKG  G     G +G +G  G +G  GE
Sbjct: 679  TGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGE 738

Query: 1569 PGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGS--------- 1619
             G PG  G +G++G  G  G  G  G KG+ G  G +GP G  G  G + S         
Sbjct: 739  KGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCT 798

Query: 1620 ------------TGR----PGLLGKKGEPGLPGDLGPVGQTGQRGRQG---DSGIPGY-G 1659
                        +GR       L + G PG+PG  GP+G  G RG  G     G+PG  G
Sbjct: 799  DVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVG 858

Query: 1660 QMGRKGVKGPRGFPGDAGQKGDIG-----NPGIPGGPGPKGFRGLALTVGLKGEEGSRGL 1714
              GR GV+G +G PG  G+KG  G       G PG PGP+G  G++   G  G+ G  G 
Sbjct: 859  VPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKE-GPPGDPGLPGK 917

Query: 1715 PGPPGQRGIKGMAGQP 1730
             G  G+ GI+G  G P
Sbjct: 918  DGDHGKPGIQGQPGPP 933



 Score =  182 bits (461), Expect = 5e-45
 Identities = 118/334 (35%), Positives = 147/334 (44%), Gaps = 74/334 (22%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PGIPG  G RGL   KG  G  G +G +G  G PG+ G  G  G  G  G  G+ G+ G+
Sbjct: 604  PGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGI 663

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD 1513
            +G  G  G  G+ G  G  GE G  G PGI+G+KGD G+QG  G +G  G+ G +G PG 
Sbjct: 664  QGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQ 723

Query: 1514 PGNPGQNNNIKGQKGSKGEQG---------------------RQGRSGQKGVQGSPSSRG 1552
             G  G ++  KG++G KGE G                      +G+ G  G QG P   G
Sbjct: 724  QGIQG-HHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDG 782

Query: 1553 SRGRE-------------------------------------------------GQRGLR 1563
              GRE                                                 G  G R
Sbjct: 783  KPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPR 842

Query: 1564 GVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRP 1623
            G+ G PG  G  G +G  G  G +G +G PGR GEKGSQG   P G  G  G  G  G P
Sbjct: 843  GLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYP-GEQGPPGPPGPEGPP 901

Query: 1624 GLL--GKKGEPGLPGDLGPVGQTGQRGRQGDSGI 1655
            G+   G  G+PGLPG  G  G+ G +G+ G  GI
Sbjct: 902  GISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGI 935



 Score =  111 bits (278), Expect = 8e-24
 Identities = 77/230 (33%), Positives = 98/230 (42%), Gaps = 49/230 (21%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G  G +G +G+   +G QG  G++G RGE G PGVRG  G +G+ G+ G  G  G KG  
Sbjct: 710  GQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQP 769

Query: 1455 GFSGPKGGHGDDGIDGLDGEE-------------------------GC------HGFPGI 1483
            G  GP+G  G DG  G +  E                          C      HG PGI
Sbjct: 770  GDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGI 829

Query: 1484 KGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNN--NIKGQKGSKGEQG-----RQ 1536
             G  G  G +G  G  G PG+ G  G  G PG PG      + G+ G KG QG      Q
Sbjct: 830  PGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQ 889

Query: 1537 GRSG-----------QKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPT 1575
            G  G           ++G  G P   G  G  G+ G++G  G PG   P+
Sbjct: 890  GPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPS 939



 Score =  107 bits (267), Expect = 1e-22
 Identities = 63/188 (33%), Positives = 108/188 (57%), Gaps = 6/188 (3%)

Query: 438 TKEADIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFYIT 497
           T   D+ F++DGS S+  + FE +K++++ +T+ F IGP  ++VGVVQYSD   +E  + 
Sbjct: 33  TAPTDLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQYSDYPVLEIPLG 92

Query: 498 DYSNDIDLRKAIFNIKQLTGGTYTGKALDYILQIIKNGMKDRMSKVPCYLIVLTDGMSTD 557
            Y +   L  A+ +I  L G T TGKA+ + L  +       ++K+    +VLTDG S D
Sbjct: 93  SYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKSSRFLTKI---AVVLTDGKSQD 149

Query: 558 RVVEPAKRLRAEQITVHAVGIGAANK-IELQEIAGKEER--VSFGQNFDALKSIKNEVVR 614
            V + A+  R  +IT+ A+G+G+  +  EL+ IA K     V + +++ A+  I+  + +
Sbjct: 150 DVKDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYVEDYIAISKIREVMKQ 209

Query: 615 EICAEKGC 622
           ++C E  C
Sbjct: 210 KLCEESVC 217



 Score =  105 bits (261), Expect = 7e-22
 Identities = 66/220 (30%), Positives = 118/220 (53%), Gaps = 13/220 (5%)

Query: 622 CEDMKADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGADKTQIGVVQFSDKTKEEFQ 681
           C     D++F++D S+S+G ENF  +K ++ N+     IG    Q+GVVQ+SD    E  
Sbjct: 31  CRTAPTDLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQYSDYPVLEIP 90

Query: 682 LNRYFTQQEISDAIDRMSLINEGTLTGKALNFVGQYFTHSKGARLGAKKFLILITDGVAQ 741
           L  Y + + ++ A++ +  +   T TGKA+ F   Y   +K +R    K  +++TDG +Q
Sbjct: 91  LGSYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYL-FAKSSRF-LTKIAVVLTDGKSQ 148

Query: 742 DDVRDPARILRGKDVTIFSVGVYNANR-SQLEEISG--DSSLVFHVENFDHLKALERKLI 798
           DDV+D A+  R   +T+F++GV +    ++L  I+    S+ VF+VE++  +  +   + 
Sbjct: 149 DDVKDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYVEDYIAISKIREVMK 208

Query: 799 FRVCALHDC-KRITL-------LDVVFVLDHSGSIKKQYQ 830
            ++C    C  RI +        D++  LD +  +KK+ Q
Sbjct: 209 QKLCEESVCPTRIPVAARDERGFDILLGLDVNKKVKKRIQ 248



 Score = 82.8 bits (203), Expect = 4e-15
 Identities = 54/136 (39%), Positives = 64/136 (47%), Gaps = 15/136 (11%)

Query: 1379 GNIAERTCCCTFCKCPGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGD 1438
            G I     C +    PGIPGP G  G +  +G  GL G       DG PG+ G  G  G 
Sbjct: 812  GRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPG------RDGVPGLVGVPGRPGV 865

Query: 1439 KGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGI--KGEKGDPGSQGSP 1496
            +G+ G PG  G+KG +GF  P       G  G  G  G  G PGI  +G  GDPG  G  
Sbjct: 866  RGLKGLPGRNGEKGSQGFGYP-------GEQGPPGPPGPEGPPGISKEGPPGDPGLPGKD 918

Query: 1497 GSRGAPGQYGEKGFPG 1512
            G  G PG  G+ G PG
Sbjct: 919  GDHGKPGIQGQPGPPG 934



 Score = 81.6 bits (200), Expect = 9e-15
 Identities = 52/186 (27%), Positives = 102/186 (54%), Gaps = 11/186 (5%)

Query: 814 DVVFVLDHSGSIKKQYQDHMINLTIHLVKKADVGRDRVQFGALKYSDQPNILFYLNTYSN 873
           D+VF+LD S S+  +  + +    +++ K  D+G   +Q G ++YSD P +   L +Y +
Sbjct: 37  DLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQYSDYPVLEIPLGSYDS 96

Query: 874 RSAIIENLRKRRDTGGNTYTAKALKHA-NALFTEEHGSRIKQNVKQMLIVITDGESHDHD 932
              +   +      GGNT T KA++ A + LF     ++  + + ++ +V+TDG+S   D
Sbjct: 97  GEHLTAAVESILYLGGNTKTGKAIQFALDYLF-----AKSSRFLTKIAVVLTDGKS--QD 149

Query: 933 QLNDTALELRNKGITIFAVGVG-KANQKELEGMAGNKNNT--IYVDNFDKLKDVFTLVQE 989
            + D A   R+  IT+FA+GVG +    EL  +A   ++T   YV+++  +  +  ++++
Sbjct: 150 DVKDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYVEDYIAISKIREVMKQ 209

Query: 990 RMCTEA 995
           ++C E+
Sbjct: 210 KLCEES 215



 Score = 65.9 bits (159), Expect = 5e-10
 Identities = 53/214 (24%), Positives = 103/214 (48%), Gaps = 15/214 (7%)

Query: 4   LLIIFVLIIWTETLADQSPGPGPVYA---DVVFLVDSSDHLGPKSFPFVKTFINKMINSL 60
           L ++ VL++    LA+             D+VF++D S  +GP++F  VK ++  +  + 
Sbjct: 8   LCMVLVLLLQNSVLAEDGEVRSSCRTAPTDLVFILDGSYSVGPENFEIVKKWLVNITKNF 67

Query: 61  PIEANKYRVALAQYSDEFHSEFHLSTFKGRSPMLNHLKKNFQFIGGSLQIGKALQEAHRT 120
            I     +V + QYSD    E  L ++      L    ++  ++GG+ + GKA+Q A   
Sbjct: 68  DIGPKFIQVGVVQYSDYPVLEIPLGSYDS-GEHLTAAVESILYLGGNTKTGKAIQFALDY 126

Query: 121 YFSAPINGRDRKQFPPILVVLASAESEDEVEEASKALQKDGVKIISVGVQKASEE-NLKA 179
            F+     +  +    I VVL   +S+D+V++A++A +   + + ++GV   +E+  L+A
Sbjct: 127 LFA-----KSSRFLTKIAVVLTDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRA 181

Query: 180 MATSHFHFNLRTIRDLSTFSQNMTQIIKDVTKYK 213
           +A       +  + D    S+     I++V K K
Sbjct: 182 IANKPSSTYVFYVEDYIAISK-----IREVMKQK 210



 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 41/171 (23%), Positives = 81/171 (47%), Gaps = 21/171 (12%)

Query: 2291 DVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPNT 2350
            D+ F++D S  VG + F+ VK ++ ++   F I P  +      +V V+ YS        
Sbjct: 37   DLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFI------QVGVVQYS-------- 82

Query: 2351 EECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLRKNKVI 2410
             + PV LE  L +Y+S   +   ++    L G+   G A+Q+ +D +F      + ++ +
Sbjct: 83   -DYPV-LEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYLFA-----KSSRFL 135

Query: 2411 FVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHNDKELEELASHP 2461
              I+   T+   +D +++ +  A+    ++F    G +  D EL  +A+ P
Sbjct: 136  TKIAVVLTDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRAIANKP 186



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 45/183 (24%), Positives = 85/183 (46%), Gaps = 7/183 (3%)

Query: 236 DLVFLVDESLGTGG-NLRHLQTFLENITSSMDVKENCMRLGLMSYSNSAKTISFLKSSTT 294
           DLVF++D S   G  N   ++ +L NIT + D+    +++G++ YS+       L S  +
Sbjct: 37  DLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQYSDYPVLEIPLGSYDS 96

Query: 295 QSEFQQQIKNLSIQVGKSNTGAAIDQMRRDGFSESYGSRRAQGVPQIAVLVTHRPSDDEV 354
                  ++++    G + TG AI       F++S     ++ + +IAV++T   S D+V
Sbjct: 97  GEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKS-----SRFLTKIAVVLTDGKSQDDV 151

Query: 355 HDAALNLRLEDVNVFALSI-QGANNTQLEEIVSYPPEQTISTLKSYADLETYSTKFLKKL 413
            DAA   R   + +FA+ +     + +L  I + P    +  ++ Y  +        +KL
Sbjct: 152 KDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYVEDYIAISKIREVMKQKL 211

Query: 414 QNE 416
             E
Sbjct: 212 CEE 214



 Score = 52.0 bits (123), Expect = 7e-06
 Identities = 30/64 (46%), Positives = 32/64 (50%), Gaps = 6/64 (9%)

Query: 1669 PRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAG 1728
            P G PG  G KGD G PG PG PG  G        G  G +G  G PG PG  GI+G  G
Sbjct: 447  PPGKPGLQGPKGDPGLPGNPGYPGQPG------QDGKPGYQGIAGTPGVPGSPGIQGARG 500

Query: 1729 QPVY 1732
             P Y
Sbjct: 501  LPGY 504



 Score = 40.4 bits (93), Expect = 0.022
 Identities = 38/152 (25%), Positives = 67/152 (44%), Gaps = 12/152 (7%)

Query: 1749 KEKCPAYPTELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNS 1808
            +  C   PT+LVF LD SY V  E+F   +  + +I  + +I     P   +V +V Y+ 
Sbjct: 28   RSSCRTAPTDLVFILDGSYSVGPENFEIVKKWLVNITKNFDIG----PKFIQVGVVQYSD 83

Query: 1809 GTSYLIRWSDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYAGANVRRVA 1868
                 I    Y+  + L   +  I Y         G A++F    +F +  +   + ++A
Sbjct: 84   YPVLEIPLGSYDSGEHLTAAVESILYLGGN--TKTGKAIQFALDYLFAK--SSRFLTKIA 139

Query: 1869 VFFSNGQTASRSSIITATMEFSALDISPTVFA 1900
            V  ++G+  S+  +  A    +A D   T+FA
Sbjct: 140  VVLTDGK--SQDDVKDAAQ--AARDSKITLFA 167



 Score = 40.0 bits (92), Expect = 0.029
 Identities = 37/170 (21%), Positives = 81/170 (47%), Gaps = 21/170 (12%)

Query: 1963 DVVFLIDNSRNIAKDEFKAVKALVSSVIDNFNIASDPLISDSGDRIALLSYSPWESSRRK 2022
            D+VF++D S ++  + F+ VK  + ++  NF+I    +      ++ ++ YS +      
Sbjct: 37   DLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFI------QVGVVQYSDYPVLEIP 90

Query: 2023 MGTVKTEFDFITYDNQLLMKNHIQTSFQQLNGEATIGRALLWTTENLFPETPYLRKHKVI 2082
            +G         +YD+   +   ++ S   L G    G+A+ +  + LF ++      K+ 
Sbjct: 91   LG---------SYDSGEHLTAAVE-SILYLGGNTKTGKAIQFALDYLFAKSSRFLT-KIA 139

Query: 2083 FVVSAGENYERKEFVKMMALRAKCQGYVIFVISLGSTRKD-DMEELASYP 2131
             V++ G++   ++ VK  A  A+     +F I +GS  +D ++  +A+ P
Sbjct: 140  VVLTDGKS---QDDVKDAAQAARDSKITLFAIGVGSETEDAELRAIANKP 186


>gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [Homo
            sapiens]
          Length = 828

 Score =  302 bits (773), Expect = 3e-81
 Identities = 189/550 (34%), Positives = 272/550 (49%), Gaps = 44/550 (8%)

Query: 1295 KDKSASRGQVLLIFSDGLQSESNIM-LENQSDRLREAGLDALLVV-----------SLNT 1342
            +D+S       ++ +DG  + S    ++ Q++R RE G+    V             + +
Sbjct: 147  QDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERAREEGIRLFAVAPNQNLKEQGLRDIAS 206

Query: 1343 TAHHEFSSFEFGKRFDYRTHLTIGM---RELGKKLSQYLGNIAERTCCCTFC-KCPGIPG 1398
            T H  +       R DY T L       ++   ++ + + + A   C    C + PG  G
Sbjct: 207  TPHELY-------RNDYATMLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIPGPSG 259

Query: 1399 PHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFSG 1458
            P G RG +  KG+ G  G  G +G  G+PG+ G  G  G KG+ G  G  G+ G  G  G
Sbjct: 260  PKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKG 319

Query: 1459 PKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPG 1518
              G  G +G DG  G+ G  G PG KG+ G+ G  G PG  G+PG+ G++G  GDPG PG
Sbjct: 320  APGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPG 379

Query: 1519 QNN-----NIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPG 1573
            +         KG KG +G  G  G  G KG +G P  RG +G  G+RG  G  G PG+ G
Sbjct: 380  RRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDG 439

Query: 1574 PTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPG 1633
            P G  G  G +GP+G  G  G KG KG +G  GP+G  G +G  G         K+G  G
Sbjct: 440  PKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPG---------KQGSRG 490

Query: 1634 LPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGP 1693
             PGD GP G +GQ G +GD G PG+   G +G  G +G PG  G +G  G+ G+ G PG 
Sbjct: 491  DPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGR 550

Query: 1694 KGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCDLIRFLREHSPC--WKEK 1751
            KG +G     G  GE G RG  G PG  G  G  G P  ++CD++ ++RE   C   +++
Sbjct: 551  KGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKR 610

Query: 1752 CPAYPTELVFALDNSYDVTEESFNKTRDIITSIVNDLN--IRENNCPVGARVAMVSY-NS 1808
            C A   ++VF +D+S  +   +F   ++ + ++VN L    ++     G RV +V Y + 
Sbjct: 611  CGA--LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHE 668

Query: 1809 GTSYLIRWSD 1818
            GT   I+  D
Sbjct: 669  GTFEAIQLDD 678



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 55/165 (33%), Positives = 83/165 (50%), Gaps = 17/165 (10%)

Query: 613 VREICAEKGCEDM--KADIMFLVDSSWSIGNENFRKMKIFMKNLLTKI-QIGADK----- 664
           VRE C    CE      D++F++DSS SIG  NF   K F+ N++ ++  I  D      
Sbjct: 598 VRETCGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETG 657

Query: 665 TQIGVVQFS-DKTKEEFQLN--RYFTQQEISDAIDRMSLINEGTLTGKALNFVGQYFTHS 721
           T++GVVQ+S + T E  QL+  R  +     +A+  +  I  GT T  AL F        
Sbjct: 658 TRVGVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLI-K 716

Query: 722 KGARLGAKKFLILITDGVAQDDVRDP---ARILRGKDVTIFSVGV 763
           +  R   + F ++ITDG  + D RD     R L  +DVT+ ++G+
Sbjct: 717 ESRRQKTRVFAVVITDG--RHDPRDDDLNLRALCDRDVTVTAIGI 759



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 54/164 (32%), Positives = 80/164 (48%), Gaps = 24/164 (14%)

Query: 434 GCVDTKEA----DIHFLIDGSSSIQEKQFEQIKRFMLE-VTEMFSIGPDK-----VRVGV 483
           GC D ++     D+ F+ID S SI    F   K F++  V  + +I  D       RVGV
Sbjct: 603 GCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGV 662

Query: 484 VQYSDDTEVEFYITDYSNDID----LRKAIFNIKQLTGGTYTGKALDYIL-QIIKNGMKD 538
           VQYS +   E    D    ID     ++A+ N++ + GGT+T  AL +   ++IK   + 
Sbjct: 663 VQYSHEGTFEAIQLD-DERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIK---ES 718

Query: 539 RMSKVPCYLIVLTDGMSTDRVVEPAKRLRA---EQITVHAVGIG 579
           R  K   + +V+TDG    R  +    LRA     +TV A+GIG
Sbjct: 719 RRQKTRVFAVVITDGRHDPR--DDDLNLRALCDRDVTVTAIGIG 760



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 63/223 (28%), Positives = 100/223 (44%), Gaps = 35/223 (15%)

Query: 802 CALHDC-KRITLLDVVFVLDHSGSI-------KKQYQDHMINLTIHLVKKADVGRDRVQF 853
           C   DC KR   LDVVFV+D S SI       +K +  +++N  +  + K        + 
Sbjct: 602 CGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVN-RLGAIAKDPKSETGTRV 660

Query: 854 GALKYSDQPN---ILFYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKHANALFTEEHGS 910
           G ++YS +     I        + S+  E ++      G T+T  ALK A     +E  S
Sbjct: 661 GVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKE--S 718

Query: 911 RIKQNVKQMLIVITDGESHD--HDQLNDTALELRNKGITIFAVGVG-----KANQKELEG 963
           R +Q  +   +VITDG  HD   D LN  A  L ++ +T+ A+G+G     K   + L  
Sbjct: 719 R-RQKTRVFAVVITDGR-HDPRDDDLNLRA--LCDRDVTVTAIGIGDMFHEKHESENLYS 774

Query: 964 MAGNK-----NNTIYVD-----NFDKLKDVFTLVQERMCTEAP 996
           +A +K     N T++ D       D ++DV     + +C + P
Sbjct: 775 IACDKPQQVRNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLP 817



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 44/176 (25%), Positives = 78/176 (44%), Gaps = 13/176 (7%)

Query: 2290 MDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPN 2349
            +DV F+ID+S+ +G   F   K F+ +V++          S  G RV V+ YS  G    
Sbjct: 614  LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEG---- 669

Query: 2350 TEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLRKNKV 2409
            T E    ++ D    +S+   K  +++ + + G  +   AL++  D +   +   +    
Sbjct: 670  TFEA---IQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVF 726

Query: 2410 IFVISAGETNSLDKDVLRNVSLRAKC-QGYSIFVFSFGPKHNDK-ELEELASHPLD 2463
              VI+ G  +  D D    ++LRA C +  ++     G   ++K E E L S   D
Sbjct: 727  AVVITDGRHDPRDDD----LNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACD 778



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 55/218 (25%), Positives = 96/218 (44%), Gaps = 30/218 (13%)

Query: 30  DVVFLVDSSDHLGPKSFPFVKTFINKMINSL------PIEANKYRVALAQYSDEFHSEFH 83
           DVVF++DSS+ +G  +F   K F+  ++N L      P      RV + QYS E   E  
Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFE-A 673

Query: 84  LSTFKGRSPMLNHLK---KNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRKQFPPILVV 140
           +     R   L+  K   KN ++I G      AL+ A    +   I    R++     VV
Sbjct: 674 IQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFA----YDRLIKESRRQKTRVFAVV 729

Query: 141 LASAESEDEVEEAS-KALQKDGVKIISVGV-----QKASEENLKAMATSHFHFNLRTIRD 194
           +     +   ++ + +AL    V + ++G+     +K   ENL ++A        + +R+
Sbjct: 730 ITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACD----KPQQVRN 785

Query: 195 LSTFSQNMTQ-IIKDVTKYKEGAVDADMQVHFP-ISCQ 230
           ++ FS  + +  I D+    E  +  D Q+  P + CQ
Sbjct: 786 MTLFSDLVAEKFIDDM----EDVLCPDPQIVCPDLPCQ 819



 Score = 38.5 bits (88), Expect = 0.085
 Identities = 45/178 (25%), Positives = 79/178 (44%), Gaps = 17/178 (9%)

Query: 1962 MDVVFLIDNSRNIAKDEFKAVKALVSSVIDNFN-IASDPLISDSGDRIALLSYSPWESSR 2020
            +DVVF+ID+S +I    F   K  V +V++    IA DP  S++G R+ ++ YS      
Sbjct: 614  LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPK-SETGTRVGVVQYS------ 666

Query: 2021 RKMGTVKT-EFDFITYDNQLLMKNHIQTSFQQLNGEATIGRALLWTTENLFPETPYLRKH 2079
               GT +  + D    D+    K  ++ + + + G      AL +  + L  E+   +  
Sbjct: 667  -HEGTFEAIQLDDERIDSLSSFKEAVK-NLEWIAGGTWTPSALKFAYDRLIKESRRQKTR 724

Query: 2080 KVIFVVSAGENYERKEFVKMMALRAKC-QGYVIFVISLGST--RKDDMEELASYPLDQ 2134
                V++ G +  R + +    LRA C +   +  I +G     K + E L S   D+
Sbjct: 725  VFAVVITDGRHDPRDDDLN---LRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDK 779



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 44/179 (24%), Positives = 86/179 (48%), Gaps = 18/179 (10%)

Query: 982  DVFTLVQERM-CTEAPEVCHLQEADVIFLCDGSDRVSNSDFVTMTTFLSDLIDNF----- 1035
            DV T V+E   C +  + C     DV+F+ D S+ +  ++F     F+ ++++       
Sbjct: 593  DVMTYVRETCGCCDCEKRCGA--LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAK 650

Query: 1036 DIQSQR-MKIGMAQFG--SNYQSI-IELKNSLTKTQWKTQIQNVSKSGGFPRIDFALKKV 1091
            D +S+   ++G+ Q+     +++I ++ +   + + +K  ++N+    G      ALK  
Sbjct: 651  DPKSETGTRVGVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFA 710

Query: 1092 SNMFNLHAGGRRNAGVPQTLVVITSG--DPRYDVADAVKTLKDLGICVLVLGIGDVYKE 1148
             +   +    R+   V    VVIT G  DPR D  + ++ L D  + V  +GIGD++ E
Sbjct: 711  YDRL-IKESRRQKTRV--FAVVITDGRHDPRDDDLN-LRALCDRDVTVTAIGIGDMFHE 765


>gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Homo
            sapiens]
          Length = 918

 Score =  302 bits (773), Expect = 3e-81
 Identities = 189/550 (34%), Positives = 272/550 (49%), Gaps = 44/550 (8%)

Query: 1295 KDKSASRGQVLLIFSDGLQSESNIM-LENQSDRLREAGLDALLVV-----------SLNT 1342
            +D+S       ++ +DG  + S    ++ Q++R RE G+    V             + +
Sbjct: 147  QDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERAREEGIRLFAVAPNQNLKEQGLRDIAS 206

Query: 1343 TAHHEFSSFEFGKRFDYRTHLTIGM---RELGKKLSQYLGNIAERTCCCTFC-KCPGIPG 1398
            T H  +       R DY T L       ++   ++ + + + A   C    C + PG  G
Sbjct: 207  TPHELY-------RNDYATMLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIPGPSG 259

Query: 1399 PHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFSG 1458
            P G RG +  KG+ G  G  G +G  G+PG+ G  G  G KG+ G  G  G+ G  G  G
Sbjct: 260  PKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKG 319

Query: 1459 PKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPG 1518
              G  G +G DG  G+ G  G PG KG+ G+ G  G PG  G+PG+ G++G  GDPG PG
Sbjct: 320  APGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPG 379

Query: 1519 QNN-----NIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPG 1573
            +         KG KG +G  G  G  G KG +G P  RG +G  G+RG  G  G PG+ G
Sbjct: 380  RRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDG 439

Query: 1574 PTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPG 1633
            P G  G  G +GP+G  G  G KG KG +G  GP+G  G +G  G         K+G  G
Sbjct: 440  PKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPG---------KQGSRG 490

Query: 1634 LPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGP 1693
             PGD GP G +GQ G +GD G PG+   G +G  G +G PG  G +G  G+ G+ G PG 
Sbjct: 491  DPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGR 550

Query: 1694 KGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCDLIRFLREHSPC--WKEK 1751
            KG +G     G  GE G RG  G PG  G  G  G P  ++CD++ ++RE   C   +++
Sbjct: 551  KGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKR 610

Query: 1752 CPAYPTELVFALDNSYDVTEESFNKTRDIITSIVNDLN--IRENNCPVGARVAMVSY-NS 1808
            C A   ++VF +D+S  +   +F   ++ + ++VN L    ++     G RV +V Y + 
Sbjct: 611  CGA--LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHE 668

Query: 1809 GTSYLIRWSD 1818
            GT   I+  D
Sbjct: 669  GTFEAIQLDD 678



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 55/165 (33%), Positives = 83/165 (50%), Gaps = 17/165 (10%)

Query: 613 VREICAEKGCEDM--KADIMFLVDSSWSIGNENFRKMKIFMKNLLTKI-QIGADK----- 664
           VRE C    CE      D++F++DSS SIG  NF   K F+ N++ ++  I  D      
Sbjct: 598 VRETCGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETG 657

Query: 665 TQIGVVQFS-DKTKEEFQLN--RYFTQQEISDAIDRMSLINEGTLTGKALNFVGQYFTHS 721
           T++GVVQ+S + T E  QL+  R  +     +A+  +  I  GT T  AL F        
Sbjct: 658 TRVGVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLI-K 716

Query: 722 KGARLGAKKFLILITDGVAQDDVRDP---ARILRGKDVTIFSVGV 763
           +  R   + F ++ITDG  + D RD     R L  +DVT+ ++G+
Sbjct: 717 ESRRQKTRVFAVVITDG--RHDPRDDDLNLRALCDRDVTVTAIGI 759



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 54/164 (32%), Positives = 80/164 (48%), Gaps = 24/164 (14%)

Query: 434 GCVDTKEA----DIHFLIDGSSSIQEKQFEQIKRFMLE-VTEMFSIGPDK-----VRVGV 483
           GC D ++     D+ F+ID S SI    F   K F++  V  + +I  D       RVGV
Sbjct: 603 GCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGV 662

Query: 484 VQYSDDTEVEFYITDYSNDID----LRKAIFNIKQLTGGTYTGKALDYIL-QIIKNGMKD 538
           VQYS +   E    D    ID     ++A+ N++ + GGT+T  AL +   ++IK   + 
Sbjct: 663 VQYSHEGTFEAIQLD-DERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIK---ES 718

Query: 539 RMSKVPCYLIVLTDGMSTDRVVEPAKRLRA---EQITVHAVGIG 579
           R  K   + +V+TDG    R  +    LRA     +TV A+GIG
Sbjct: 719 RRQKTRVFAVVITDGRHDPR--DDDLNLRALCDRDVTVTAIGIG 760



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 63/223 (28%), Positives = 100/223 (44%), Gaps = 35/223 (15%)

Query: 802 CALHDC-KRITLLDVVFVLDHSGSI-------KKQYQDHMINLTIHLVKKADVGRDRVQF 853
           C   DC KR   LDVVFV+D S SI       +K +  +++N  +  + K        + 
Sbjct: 602 CGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVN-RLGAIAKDPKSETGTRV 660

Query: 854 GALKYSDQPN---ILFYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKHANALFTEEHGS 910
           G ++YS +     I        + S+  E ++      G T+T  ALK A     +E  S
Sbjct: 661 GVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKE--S 718

Query: 911 RIKQNVKQMLIVITDGESHD--HDQLNDTALELRNKGITIFAVGVG-----KANQKELEG 963
           R +Q  +   +VITDG  HD   D LN  A  L ++ +T+ A+G+G     K   + L  
Sbjct: 719 R-RQKTRVFAVVITDGR-HDPRDDDLNLRA--LCDRDVTVTAIGIGDMFHEKHESENLYS 774

Query: 964 MAGNK-----NNTIYVD-----NFDKLKDVFTLVQERMCTEAP 996
           +A +K     N T++ D       D ++DV     + +C + P
Sbjct: 775 IACDKPQQVRNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLP 817



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 44/176 (25%), Positives = 78/176 (44%), Gaps = 13/176 (7%)

Query: 2290 MDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPN 2349
            +DV F+ID+S+ +G   F   K F+ +V++          S  G RV V+ YS  G    
Sbjct: 614  LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEG---- 669

Query: 2350 TEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLRKNKV 2409
            T E    ++ D    +S+   K  +++ + + G  +   AL++  D +   +   +    
Sbjct: 670  TFEA---IQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVF 726

Query: 2410 IFVISAGETNSLDKDVLRNVSLRAKC-QGYSIFVFSFGPKHNDK-ELEELASHPLD 2463
              VI+ G  +  D D    ++LRA C +  ++     G   ++K E E L S   D
Sbjct: 727  AVVITDGRHDPRDDD----LNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACD 778



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 56/221 (25%), Positives = 98/221 (44%), Gaps = 30/221 (13%)

Query: 30  DVVFLVDSSDHLGPKSFPFVKTFINKMINSL------PIEANKYRVALAQYSDEFHSEFH 83
           DVVF++DSS+ +G  +F   K F+  ++N L      P      RV + QYS E   E  
Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFE-A 673

Query: 84  LSTFKGRSPMLNHLK---KNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRKQFPPILVV 140
           +     R   L+  K   KN ++I G      AL+ A    +   I    R++     VV
Sbjct: 674 IQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFA----YDRLIKESRRQKTRVFAVV 729

Query: 141 LASAESEDEVEEAS-KALQKDGVKIISVGV-----QKASEENLKAMATSHFHFNLRTIRD 194
           +     +   ++ + +AL    V + ++G+     +K   ENL ++A        + +R+
Sbjct: 730 ITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACD----KPQQVRN 785

Query: 195 LSTFSQNMTQ-IIKDVTKYKEGAVDADMQVHFP-ISCQKDS 233
           ++ FS  + +  I D+    E  +  D Q+  P + CQ D+
Sbjct: 786 MTLFSDLVAEKFIDDM----EDVLCPDPQIVCPDLPCQTDA 822



 Score = 38.5 bits (88), Expect = 0.085
 Identities = 45/178 (25%), Positives = 79/178 (44%), Gaps = 17/178 (9%)

Query: 1962 MDVVFLIDNSRNIAKDEFKAVKALVSSVIDNFN-IASDPLISDSGDRIALLSYSPWESSR 2020
            +DVVF+ID+S +I    F   K  V +V++    IA DP  S++G R+ ++ YS      
Sbjct: 614  LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPK-SETGTRVGVVQYS------ 666

Query: 2021 RKMGTVKT-EFDFITYDNQLLMKNHIQTSFQQLNGEATIGRALLWTTENLFPETPYLRKH 2079
               GT +  + D    D+    K  ++ + + + G      AL +  + L  E+   +  
Sbjct: 667  -HEGTFEAIQLDDERIDSLSSFKEAVK-NLEWIAGGTWTPSALKFAYDRLIKESRRQKTR 724

Query: 2080 KVIFVVSAGENYERKEFVKMMALRAKC-QGYVIFVISLGST--RKDDMEELASYPLDQ 2134
                V++ G +  R + +    LRA C +   +  I +G     K + E L S   D+
Sbjct: 725  VFAVVITDGRHDPRDDDLN---LRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDK 779



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 44/179 (24%), Positives = 86/179 (48%), Gaps = 18/179 (10%)

Query: 982  DVFTLVQERM-CTEAPEVCHLQEADVIFLCDGSDRVSNSDFVTMTTFLSDLIDNF----- 1035
            DV T V+E   C +  + C     DV+F+ D S+ +  ++F     F+ ++++       
Sbjct: 593  DVMTYVRETCGCCDCEKRCGA--LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAK 650

Query: 1036 DIQSQR-MKIGMAQFG--SNYQSI-IELKNSLTKTQWKTQIQNVSKSGGFPRIDFALKKV 1091
            D +S+   ++G+ Q+     +++I ++ +   + + +K  ++N+    G      ALK  
Sbjct: 651  DPKSETGTRVGVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFA 710

Query: 1092 SNMFNLHAGGRRNAGVPQTLVVITSG--DPRYDVADAVKTLKDLGICVLVLGIGDVYKE 1148
             +   +    R+   V    VVIT G  DPR D  + ++ L D  + V  +GIGD++ E
Sbjct: 711  YDRL-IKESRRQKTRV--FAVVITDGRHDPRDDDLN-LRALCDRDVTVTAIGIGDMFHE 765


>gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]
          Length = 1028

 Score =  281 bits (719), Expect = 6e-75
 Identities = 174/495 (35%), Positives = 241/495 (48%), Gaps = 52/495 (10%)

Query: 1335 LLVVSLNTTAHHEFSSFEFGKRFDYRTHLTIGMRELGKKLSQYLGNIAERTCCCTFCK-C 1393
            L +++ + T    F++ ++G+  D    ++    +    +   + N  E+ CC   C+  
Sbjct: 200  LSIIATDHTYRRNFTAADWGQSRDAEEAIS----QTIDTIVDMIKNNVEQVCCSFECQPA 255

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
             G PG  G  G +  +G  GL G +G  G+ G PG  G  G QG KG  G  G  G +G 
Sbjct: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD 1513
            KG+ G KG  G DG+DG+ GE G  G PG KG  G  G QG PG +G PG +G KG  G+
Sbjct: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375

Query: 1514 PGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPG 1573
            PG             + GE GR G SG  G +G P      G  G  G +G +G+ GNPG
Sbjct: 376  PG-------------ADGEAGRPGSSGPSGDEGQP------GEPGPPGEKGEAGDEGNPG 416

Query: 1574 PTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPG 1633
            P G  G  G  G +G +G PG +G +G  G+ GPQG  G  G  G  G PG  G  G  G
Sbjct: 417  PDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKG 476

Query: 1634 LPGDLGPVGQTGQRGRQGDSGIPG-YGQMGRKGVKGP-----RGFPGDAGQKGDIGNPGI 1687
              GD GP G  G RG  G +G PG  G MG +G  GP      GFPG  G  G+ G PGI
Sbjct: 477  YRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGI 536

Query: 1688 ---PGGPGPKGFRGLA-------LTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCDL 1737
                G PG KG  G A         +  +G +G++G  GP G +G  G  G P   +C++
Sbjct: 537  NGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPDECEI 596

Query: 1738 IRFLREHSPCWKEKCPAYPTELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPV 1797
            +  + +   C + KC   P +L+F LD+S  +  ++F   +D +  +++ L         
Sbjct: 597  LDIIMKMCSCCECKCG--PIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRL--------- 645

Query: 1798 GARVAMVSYNSGTSY 1812
             +R  +V +  G SY
Sbjct: 646  -SRDELVKFEPGQSY 659



 Score = 65.1 bits (157), Expect = 8e-10
 Identities = 92/393 (23%), Positives = 158/393 (40%), Gaps = 62/393 (15%)

Query: 611 EVVREICAEKGCEDMKADIMFLVDSSWSIGNENFRKMKIFMKNLLTK------IQIGADK 664
           +++ ++C+   C+    D++F++DSS SIG +NF   K F+  ++ +      ++    +
Sbjct: 598 DIIMKMCSCCECKCGPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQ 657

Query: 665 TQIGVVQFSDKTKEEFQLNR---YFTQQEISDAIDRMSLINEGTLTGKALNFV-GQYFTH 720
           +  GVVQ+S    +E    R       QE+ +AI  +  +  GT TG+AL +   Q    
Sbjct: 658 SYAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPP 717

Query: 721 SKGARLGAKKFLILITDGVAQDDVRD--PARILRGKDVTIFSVGV-----YNANRSQLEE 773
           S   R+      ++ITDG   D  RD  P  +L    + + SVG+     +     QL  
Sbjct: 718 SPNNRIA-----LVITDG-RSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNV 771

Query: 774 IS--------GDSSLVFHVENFDHL--KALERKLIFRVCALHDCKRITL-------LDVV 816
           IS        G   L    EN+  L   A  + +  ++C    C   T         D+ 
Sbjct: 772 ISCQGLAPSQGRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADIT 831

Query: 817 FVLDHSGSIKKQYQDHMINLTIHLVK------KADVGRDRVQFGALKYS------DQPNI 864
            +LD S S+     D        L +      + D   D V+   ++YS       +   
Sbjct: 832 ILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHD-VRVAVVQYSGTGQQRPERAS 890

Query: 865 LFYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKHANALFTEEHGSRIKQNVKQMLIVIT 924
           L +L  Y+  ++ ++ +    D    T    AL +    + E          K+ L++ +
Sbjct: 891 LQFLQNYTALASAVDAMDFINDA---TDVNDALGYVTRFYREASSGA----AKKRLLLFS 943

Query: 925 DGESHDHD--QLNDTALELRNKGITIFAVGVGK 955
           DG S       +     E +  GI IF V VG+
Sbjct: 944 DGNSQGATPAAIEKAVQEAQRAGIEIFVVVVGR 976



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 84/376 (22%), Positives = 142/376 (37%), Gaps = 56/376 (14%)

Query: 236 DLVFLVDESLGTG-GNLRHLQTFLENITSSMDVKE------NCMRLGLMSYSNSA--KTI 286
           DL+F++D S   G  N    + F+  +   +   E           G++ YS+S   + +
Sbjct: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674

Query: 287 SFLKSSTTQ-SEFQQQIKNLSIQVGKSNTGAAIDQMRRDGFSESYGSRRAQGVPQIAVLV 345
           S    S     E ++ IK+L    G + TG A+   R      S  +R       IA+++
Sbjct: 675 SLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNR-------IALVI 727

Query: 346 THRPSDDEVHDAALNLRLED-VNVFALSIQGANNTQLEEIVSYPPEQTISTLKSYADLET 404
           T   SD +     LN+     + V ++ I+        ++  + P      + S   L  
Sbjct: 728 TDGRSDTQRDTTPLNVLCSPGIQVVSVGIK--------DVFDFIPGSDQLNVISCQGLAP 779

Query: 405 YSTKFLKKLQNEIWSQISTYAEQRNLDKTGCVDTK------------EADIHFLIDGSSS 452
              +    L  E ++++   A  +N+    C+D K             ADI  L+DGS+S
Sbjct: 780 SQGRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSAS 839

Query: 453 IQEKQFEQIKRFMLEVTEMFSIG-----PDKVRVGVVQYS---DDTEVEFYITDYSNDID 504
           +    F+  KRF   + E F           VRV VVQYS           +    N   
Sbjct: 840 VGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTA 899

Query: 505 LRKAIFNIKQLTGGTYTGKALDYILQIIKNGMKDRMSKVPCYLIVLTDGMS-------TD 557
           L  A+  +  +   T    AL Y+ +  +        K    L++ +DG S        +
Sbjct: 900 LASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKK---RLLLFSDGNSQGATPAAIE 956

Query: 558 RVVEPAKRLRAEQITV 573
           + V+ A+R   E   V
Sbjct: 957 KAVQEAQRAGIEIFVV 972



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 68/273 (24%), Positives = 123/273 (45%), Gaps = 46/273 (16%)

Query: 797  LIFRVCALHDCKRITLLDVVFVLDHSGSIKKQYQDHMINLTIHLVKKADVGRDR-VQF-- 853
            +I ++C+  +CK    +D++FVLD S SI  Q  +   +  + ++ +  + RD  V+F  
Sbjct: 599  IIMKMCSCCECK-CGPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDR--LSRDELVKFEP 655

Query: 854  -----GALKYSD---QPNILFYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKHA-NALF 904
                 G ++YS    Q ++     +  N   + E ++  +   G T+T +AL++  + L 
Sbjct: 656  GQSYAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLL 715

Query: 905  TEEHGSRIKQNVKQMLIVITDGESHDHDQLNDTALE-LRNKGITIFAVGV---------- 953
                 +RI        +VITDG S    Q + T L  L + GI + +VG+          
Sbjct: 716  PPSPNNRIA-------LVITDGRSDT--QRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGS 766

Query: 954  GKANQKELEGMA---GNKNNTIYVDNF-DKLKDVFTL-VQERMCTE--APE----VCHLQ 1002
             + N    +G+A   G    ++  +N+ + L+D F   V  ++C +   P+    +    
Sbjct: 767  DQLNVISCQGLAPSQGRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSS 826

Query: 1003 EADVIFLCDGSDRVSNSDFVTMTTFLSDLIDNF 1035
             AD+  L DGS  V + +F T   F   L + F
Sbjct: 827  PADITILLDGSASVGSHNFDTTKRFAKRLAERF 859



 Score = 45.8 bits (107), Expect = 5e-04
 Identities = 37/161 (22%), Positives = 69/161 (42%), Gaps = 13/161 (8%)

Query: 2290 MDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPN 2349
            +D+ F++D+S+ +G   F+  K F+  V+D                  V+ YS       
Sbjct: 614  IDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSH------ 667

Query: 2350 TEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLRKNKV 2409
              +   ++     +  ++ ++K  ++  Q + G  F G ALQ+T D +   +PN   N++
Sbjct: 668  -SQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPN---NRI 723

Query: 2410 IFVISAGETNSLDKDVLRNVSLRAKCQGYSI---FVFSFGP 2447
              VI+ G +++       NV      Q  S+    VF F P
Sbjct: 724  ALVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIP 764



 Score = 38.5 bits (88), Expect = 0.085
 Identities = 39/170 (22%), Positives = 79/170 (46%), Gaps = 28/170 (16%)

Query: 1935 LRRCALCYDKCFPNACIREAFLPEDSYMDVVFLIDNSRNIAKDEFKAVKALVSSVIDNFN 1994
            ++ C+ C  KC P              +D++F++D+S +I    F+  K  V  VID   
Sbjct: 601  MKMCSCCECKCGP--------------IDLLFVLDSSESIGLQNFEIAKDFVVKVID--R 644

Query: 1995 IASDPLIS-DSGDRIA-LLSYSPWESSRRKMGTVKTEFDFITYDNQLLMKNHIQTSFQQL 2052
            ++ D L+  + G   A ++ YS   S  ++  ++++     +  N   +K  I+ S Q +
Sbjct: 645  LSRDELVKFEPGQSYAGVVQYS--HSQMQEHVSLRSP----SIRNVQELKEAIK-SLQWM 697

Query: 2053 NGEATIGRALLWTTENLFPETPYLRKHKVIFVVSAGENYERKEFVKMMAL 2102
             G    G AL +T + L P +P    +++  V++ G +  +++   +  L
Sbjct: 698  AGGTFTGEALQYTRDQLLPPSP---NNRIALVITDGRSDTQRDTTPLNVL 744



 Score = 36.2 bits (82), Expect = 0.42
 Identities = 42/157 (26%), Positives = 65/157 (41%), Gaps = 20/157 (12%)

Query: 1747 CWKEKCPAY--------PTELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPV- 1797
            C  +KCP Y        P ++   LD S  V   +F+ T+     +           P  
Sbjct: 810  CIDKKCPDYTCPITFSSPADITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAH 869

Query: 1798 GARVAMVSYNSGTSYLIRWSDYNRKKQLLQQL----SQIKYQD-TTEPRDVGNAMRFVTR 1852
              RVA+V Y SGT    +        Q LQ      S +   D   +  DV +A+ +VTR
Sbjct: 870  DVRVAVVQY-SGTG---QQRPERASLQFLQNYTALASAVDAMDFINDATDVNDALGYVTR 925

Query: 1853 NVFKRTYAGANVRRVAVFF-SNGQTASRSSIITATME 1888
              ++   +GA  +R+ +F   N Q A+ ++I  A  E
Sbjct: 926  -FYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQE 961



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 36/135 (26%), Positives = 61/135 (45%), Gaps = 17/135 (12%)

Query: 442 DIHFLIDGSSSIQ----------EKQFEQIKRFMLEVTEMFSIGPDKV--RVGVVQYSDD 489
           D+ F++D S S+           +K     KRF+  + + +      +    G + YSD+
Sbjct: 37  DLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLRDRYYRCDRNLVWNAGALHYSDE 96

Query: 490 TEVEFYITDYSNDID-LRKAIFNIKQLTGGTYTGKALDYIL-QIIKNGMKDRMSKVPCYL 547
            E+   +T      D L+ ++  +K    GTYT  A+   L Q++  G   + +K   YL
Sbjct: 97  VEIIQGLTRMPGGRDALKSSVDAVKYFGKGTYTDCAIKKGLEQLLVGGSHLKENK---YL 153

Query: 548 IVLTDGMSTDRVVEP 562
           IV+TDG   +   EP
Sbjct: 154 IVVTDGHPLEGYKEP 168



 Score = 34.3 bits (77), Expect = 1.6
 Identities = 40/184 (21%), Positives = 67/184 (36%), Gaps = 11/184 (5%)

Query: 2291 DVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGD-RVAVLSYSPPGYMPN 2349
            D+  L+D S  VGS  F   K F   + + F  A    T    D RVAV+ YS  G    
Sbjct: 829  DITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGR--TDPAHDVRVAVVQYSGTGQQRP 886

Query: 2350 TEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLRKNKV 2409
                  +L+      +++  M         +N    +  AL + +   +    +    K 
Sbjct: 887  ERASLQFLQNYTALASAVDAMDF-------INDATDVNDALGY-VTRFYREASSGAAKKR 938

Query: 2410 IFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHNDKELEELASHPLDHHLVQL 2469
            + + S G +       +      A+  G  IFV   G + N+  +  L +     + V  
Sbjct: 939  LLLFSDGNSQGATPAAIEKAVQEAQRAGIEIFVVVVGRQVNEPHIRVLVTGKTAEYDVAY 998

Query: 2470 GRTH 2473
            G +H
Sbjct: 999  GESH 1002



 Score = 32.3 bits (72), Expect = 6.1
 Identities = 31/138 (22%), Positives = 62/138 (44%), Gaps = 14/138 (10%)

Query: 623 EDMKADIMFLVDSSWSIG------NENFRKMKIFMKNLLTKIQ---IGADKTQI---GVV 670
           +D   D+ F++D+S S+            K+K F K  +  ++      D+  +   G +
Sbjct: 32  QDCPVDLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLRDRYYRCDRNLVWNAGAL 91

Query: 671 QFSDKTKEEFQLNRYFTQQE-ISDAIDRMSLINEGTLTGKALNFVGQYFTHSKGARLGAK 729
            +SD+ +    L R    ++ +  ++D +    +GT T  A+   G       G+ L   
Sbjct: 92  HYSDEVEIIQGLTRMPGGRDALKSSVDAVKYFGKGTYTDCAIK-KGLEQLLVGGSHLKEN 150

Query: 730 KFLILITDGVAQDDVRDP 747
           K+LI++TDG   +  ++P
Sbjct: 151 KYLIVVTDGHPLEGYKEP 168



 Score = 32.3 bits (72), Expect = 6.1
 Identities = 39/166 (23%), Positives = 70/166 (42%), Gaps = 17/166 (10%)

Query: 29  ADVVFLVDSSDHLGPKSFPFVKTFINKMINSL-----PIEANKYRVALAQYS--DEFHSE 81
           AD+  L+D S  +G  +F   K F  ++            A+  RVA+ QYS   +   E
Sbjct: 828 ADITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPE 887

Query: 82  FHLSTFKGRSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRKQFPPILVVL 141
                F      L        FI  +  +  AL    R Y  A  +G  +K+    L++ 
Sbjct: 888 RASLQFLQNYTALASAVDAMDFINDATDVNDALGYVTRFYREAS-SGAAKKR----LLLF 942

Query: 142 ASAESED----EVEEASKALQKDGVKIISVGV-QKASEENLKAMAT 182
           +   S+      +E+A +  Q+ G++I  V V ++ +E +++ + T
Sbjct: 943 SDGNSQGATPAAIEKAVQEAQRAGIEIFVVVVGRQVNEPHIRVLVT 988


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  277 bits (709), Expect = 8e-74
 Identities = 161/357 (45%), Positives = 192/357 (53%), Gaps = 26/357 (7%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PG  G  GL    G+ G  G +G  G  GNPG+ G+ GP G  G  G PG  G+KG 
Sbjct: 1109 PGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGK 1168

Query: 1454 KG---FSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGF 1510
             G     GP G  G+ G  G  G  G  G PG+ G+KGD G  G PG+ G PG  GE GF
Sbjct: 1169 PGQDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGF 1227

Query: 1511 ---------PGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRG 1561
                     PG PG+PG    ++G KG+ G QG  GR G  G QG P   G  G  G  G
Sbjct: 1228 HGFPGVQGPPGPPGSPGPA--LEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGG 1285

Query: 1562 LRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTG 1621
            ++G  G PG PG  G  G +G QGP G QGNPGR G  G +G  G  G PG  G KG +G
Sbjct: 1286 IKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSG 1345

Query: 1622 RPGLLGKKGEPGLPGDLGPVGQTGQRGR----QGDSGIPGY-GQMGRKGV---KGPRGFP 1673
             PG  G +GEPGL G  GP G  G  G+    +GD+G PG  GQ G KG+   +GP+G P
Sbjct: 1346 VPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLP 1405

Query: 1674 GDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
            G  G  GD G  G+PG  G  G +G     GL G+ G+RGL GPPG  G++G  G P
Sbjct: 1406 GPTGPPGDPGRNGLPGFDGAGGRKG---DPGLPGQPGTRGLDGPPGPDGLQGPPGPP 1459



 Score =  254 bits (649), Expect = 8e-67
 Identities = 167/393 (42%), Positives = 194/393 (49%), Gaps = 63/393 (16%)

Query: 1396 IPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPG---VRGDTGPQGDKGIAGCPGAWGQKG 1452
            +PGP G  GL   KG+ G KG RG  G  G PG   + G  GP+GD G  G PG  G  G
Sbjct: 755  LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPG 814

Query: 1453 LKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQ--GSPGSRGAPGQYGEKGF 1510
            L G  G +G  G  GI G  G+ G HG PG KG+ G PG    G PG RG+PG  G  G 
Sbjct: 815  LPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGP 873

Query: 1511 PGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRG---VSG 1567
             G PG+PG    + G+ G+ G  G +G  G  G  G P   G  GR G  GL+G   + G
Sbjct: 874  IGPPGSPG----LPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQG 929

Query: 1568 EPGNPGPTGTLGAEG--------------LQGPQGSQGNPGRKGEKGSQGQKGPQGSPGL 1613
            +PG PGPTG  G++G              L G +G +G PG  G  G  G KG QG PG 
Sbjct: 930  QPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD 989

Query: 1614 MGAKGSTGRPGLLGK---KGEPGLPGDLGPVGQTGQRGRQGDSGIPG----YGQMGRKGV 1666
             G  G +G+PGL G    KG PGLPG  G +G  G +G  GD G PG     G  G  GV
Sbjct: 990  PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049

Query: 1667 KGPRGFPGDAGQKGDIGNPGI-----PGGPGPKG---------------------FRGLA 1700
             G  G PG  GQKGD G+PGI     PG PGPKG                       GL 
Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLP 1109

Query: 1701 LTVGLKGEEGSRGLPG---PPGQRGIKGMAGQP 1730
             T G KG+ G  G PG   PPG +GI G  G P
Sbjct: 1110 GTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNP 1142



 Score =  251 bits (641), Expect = 6e-66
 Identities = 157/379 (41%), Positives = 186/379 (49%), Gaps = 46/379 (12%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRG------EDGNPGVRGDTGPQGDKGIAGCPGA 1447
            PG+PG  G  G    KG  G+ G  G  G        G PG++GD G QG  G+ G  G 
Sbjct: 880  PGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGE 939

Query: 1448 WGQKGLKGFSGP-----------KGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSP 1496
             G KG  G  GP           KG  G+ G+ G+ G  G  G+ G+ G+ G PG  G P
Sbjct: 940  KGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQP 999

Query: 1497 GSRGAPGQYGEKGFPGDPG---NPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGS 1553
            G  G PG  G  G PG PG    PG    I G  G  G QG +G  G  GV G P S G 
Sbjct: 1000 GLPGPPGPKGNPGLPGQPGLIGPPGLKGTI-GDMGFPGPQGVEGPPGPSGVPGQPGSPGL 1058

Query: 1554 RGREGQRGLRGVS--GEPGNPGPTGTLGAEGLQGP---QGSQGNPGRKGEKGSQGQKGPQ 1608
             G++G +G  G+S  G PG PGP G  G  G  G    +GS G+PG  G  G+ G KG  
Sbjct: 1059 PGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQP 1118

Query: 1609 GSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVG---------QTGQRGRQGDSGIPG-Y 1658
            G PG  G  G  G  G+ G  G PGLPG+ GPVG           G++G+ G  GIPG  
Sbjct: 1119 GLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPA 1178

Query: 1659 GQMGRKGVKG-----PRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRG 1713
            GQ G  G  G     P G PG +GQKGD G PGIPG PG  G +G     G  G  G +G
Sbjct: 1179 GQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG---EPGFHGFPGVQG 1235

Query: 1714 LPGPPGQRG--IKGMAGQP 1730
             PGPPG  G  ++G  G P
Sbjct: 1236 PPGPPGSPGPALEGPKGNP 1254



 Score =  251 bits (641), Expect = 6e-66
 Identities = 164/416 (39%), Positives = 191/416 (45%), Gaps = 76/416 (18%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PG  G  G+   KG QGL G  G  G  G PG+ G  GP+G+ G+ G PG  G  GLK
Sbjct: 967  GEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLK 1026

Query: 1455 G------FSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEK 1508
            G      F GP+G  G  G  G+ G+ G  G PG KG+KGDPG   S G  G PG  GE 
Sbjct: 1027 GTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGIS-SIGLPGLPGPKGEP 1085

Query: 1509 GFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGE 1568
            G PG PGNPG   ++ G  G  G  G  G  GQ G+ G P + G  G +G  G  G  G 
Sbjct: 1086 GLPGYPGNPGIKGSV-GDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGL 1144

Query: 1569 PGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKG-----------PQGSPGLMGAK 1617
            PG PGP G  G  G  GP G +G PG+ G  G  GQKG           P G PGL G K
Sbjct: 1145 PGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQK 1204

Query: 1618 GS------TGRPGLLGKKGEPGL--------------------------------PGDLG 1639
            G        G PGL G KGEPG                                 PG  G
Sbjct: 1205 GDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPG 1264

Query: 1640 PVGQTGQRGRQGDSGIPGYGQM-GRKGVKGPRGFPGDAGQKGDIG--------------- 1683
            P G  G  G +G  G+PG G + G KG  G  G PG  G KGD G               
Sbjct: 1265 PTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNG 1324

Query: 1684 ---NPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCD 1736
               +PG+PG PG  G +G +   G  G EG  GL GPPG  G+ G +GQ +  + D
Sbjct: 1325 MKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGD 1380



 Score =  246 bits (629), Expect = 2e-64
 Identities = 158/404 (39%), Positives = 184/404 (45%), Gaps = 71/404 (17%)

Query: 1395 GIPGPHGTRGLQAMKGSQG-----LKGSRGHRGEDGNPGVRGDTGPQG----------DK 1439
            G PGP G  G +  KG +G     + G  G  G+ G PG+ G  GP G          + 
Sbjct: 394  GPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEP 453

Query: 1440 GIAGCPGAWGQKGLKGFSGPKGGHGDD----------------GIDGLDGEEGCHGFPGI 1483
            G  G PG+ G KGL+G  G KG  GD                 G+ GL G  G  GFPG 
Sbjct: 454  GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQ 513

Query: 1484 KGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKG 1543
            KGEKG  G+ G  G  G PG  G  GFPG  G PG      G KG KGE G  G  G  G
Sbjct: 514  KGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573

Query: 1544 VQGSPSSRGSRGREGQRG------LRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKG 1597
            + G+P   G  G  G +G       +G  G PGNPG  G  G  G  GP G  G PG  G
Sbjct: 574  LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPGPVG 632

Query: 1598 EKGSQGQKGPQGSPGLMGAKGSTGR----------PGLLGKKGEPGLPGDLGPVGQTGQR 1647
            EKG QG  G  G PG+ G KG  G+          PG  G+ G+ GLPGD G  GQ G  
Sbjct: 633  EKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLP 692

Query: 1648 GRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPG--------------------- 1686
            G  G  G PG   +G  G  GP+GFPG  G  G  G PG                     
Sbjct: 693  GIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPG 752

Query: 1687 --IPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAG 1728
              +PG PGP G  G    +G KG+ G  G PGPPG+ G+ G+ G
Sbjct: 753  FALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPG 796



 Score =  246 bits (627), Expect = 3e-64
 Identities = 158/370 (42%), Positives = 179/370 (48%), Gaps = 28/370 (7%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G+PGP G +G   + G  G  G+ G  G +G PG  G  GP+G+ G A  PG  G  GL 
Sbjct: 707  GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFA-LPGPPGPPGLP 765

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQ--YGEKGFPG 1512
            GF G  G  GD G  G  G  G  G  G+ G KGD G  G PG  G PG    G +G PG
Sbjct: 766  GFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPG 825

Query: 1513 DPGNPGQN-----NNIKGQKGSKGEQGRQ--GRSGQKGVQGSPSSRGSRGREGQRGLRGV 1565
             PG PG       + I G+KG  G  G    G  G++G  G P + G  G  G  GL G 
Sbjct: 826  PPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGK 885

Query: 1566 SGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGL---MGAKGSTGR 1622
            +G  G PG  G +G  G  GP G  G PGR G  G +G  G QG PGL    G KGS G 
Sbjct: 886  AGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGE 945

Query: 1623 PGL--------------LGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGVK 1667
            PGL               G+KGEPGLPG  G  G  G +G  GD G PG  GQ G  G  
Sbjct: 946  PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPP 1005

Query: 1668 GPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMA 1727
            GP+G PG  GQ G IG PG+ G  G  GF G     G  G  G  G PG PG  G KG  
Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065

Query: 1728 GQPVYSQCDL 1737
            G P  S   L
Sbjct: 1066 GDPGISSIGL 1075



 Score =  243 bits (621), Expect = 1e-63
 Identities = 167/468 (35%), Positives = 198/468 (42%), Gaps = 128/468 (27%)

Query: 1391 CKCPGIPGPHGTRGLQAMKGSQGLKG---------SRGHRGEDGNPGVRGDTGPQGDKGI 1441
            C C GI G  G RG   ++G  GL G          RG +G+DG PG  G  G +G  G+
Sbjct: 38   CDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGL 97

Query: 1442 AGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGA 1501
             G PG  G  G+ G  G  G  G  G +G  GE G  G PG  G +G PG  G PG +G 
Sbjct: 98   PGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGE 157

Query: 1502 PGQY------GEKGFPGDPGNPG------------------------------------- 1518
            PG        G KG PG PG PG                                     
Sbjct: 158  PGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGN 217

Query: 1519 QNNNIKGQKGSKGEQGRQGRSG----------------QKGVQGSPSSR----------- 1551
               N +G KG KGEQG QG  G                QKG QG P  R           
Sbjct: 218  MGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP 277

Query: 1552 -----GSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKG 1606
                 G +G +G++G  G  G+PG  G  G  G  GL G  G  G PGR GEKG +G  G
Sbjct: 278  PGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTG 337

Query: 1607 PQGSPGL----------MGAKGSTGRPGLLGKKGE---------PGLP--------GDLG 1639
            P G PGL          +G KG+ G PGL G+KGE         PGLP        G  G
Sbjct: 338  PPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG 397

Query: 1640 PVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIG----------NPGIPG 1689
            P G  G+RG++GD G PG    G  G+ G  G PG  G  G  G           PG PG
Sbjct: 398  PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG 457

Query: 1690 GPGPKGFRGLALTVGLKGEEG-------SRGLPGPPGQRGIKGMAGQP 1730
             PG  G +GL    G+KG++G         G+ GPPGQ G+ G+ G P
Sbjct: 458  PPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPP 505



 Score =  241 bits (614), Expect = 9e-63
 Identities = 152/373 (40%), Positives = 180/373 (48%), Gaps = 41/373 (10%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHR-------GEDGNPGVRGDTGPQGDKGIAGCPG 1446
            PG PGP G+ G + ++G QG+KG +G         G  G PG  G  G  G  G  G PG
Sbjct: 453  PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512

Query: 1447 AWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHG-------FPGIKGEKGDPGSQGSPGSR 1499
              G+KG  G +GPKG  G  G  G  G  G  G       FPG+KG+KG+ GS G+PG  
Sbjct: 513  QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572

Query: 1500 GAPGQYGEKGFPGDPGNPGQNNNI--KGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGRE 1557
            G PG  G+ G PG PG  G+   I  KG++G  G  G  G  G  G  G P   G  G  
Sbjct: 573  GLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPGPV 631

Query: 1558 GQRGLRGVSGEPGNPGPTGTLGAEGLQ----GPQGSQGNPGRKGEKGSQGQKGPQGSPGL 1613
            G++G++GV+G PG PG  G  G  G      G  G  GNPGR G+ G  G  G  G PGL
Sbjct: 632  GEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGL 691

Query: 1614 MGAKGSTGRPGLLG-----------------KKGEPGLPGDLGPVGQTGQRGRQGDSGIP 1656
             G  GS G PG+ G                   G PG PG +G  G  G  G  G  G P
Sbjct: 692  PGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEP 751

Query: 1657 GYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPG 1716
            G+   G  G  G  GF G  G KGD G PG PG PG  G  GL    G KG+ G  G PG
Sbjct: 752  GFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP---GPKGDVGPNGQPG 808

Query: 1717 PPGQRGIKGMAGQ 1729
            P G  G+ G+  Q
Sbjct: 809  PMGPPGLPGIGVQ 821



 Score =  233 bits (595), Expect = 1e-60
 Identities = 156/385 (40%), Positives = 180/385 (46%), Gaps = 57/385 (14%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PGP G RG   + G  G  G  G  G DG PG +G  G  G KG  G PG+ G  GL
Sbjct: 83   PGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGL 142

Query: 1454 KGFSGPKGGHGDDGIDG------LDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGE 1507
            +G  GP G  G  G  G      L G +G  G+PG  G +G PG  G PG  G PG  G 
Sbjct: 143  QGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGL 202

Query: 1508 KGFPGDPGNPGQNNNI----KGQKGSKGEQGRQGRSG----------------QKGVQGS 1547
             G PG PG PG   N+    +G KG KGEQG QG  G                QKG QG 
Sbjct: 203  MGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGL 262

Query: 1548 PSSRG----------------SRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQG 1591
            P  RG                 +G +G++G  G  G+PG  G  G  G  GL G  G  G
Sbjct: 263  PGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPG 322

Query: 1592 NPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQG 1651
             PGR GEKG +G  GP G PGL+  +  TG    +G+KG  GLPG  G  G+ G  G QG
Sbjct: 323  EPGRDGEKGQKGDTGPPGPPGLVIPRPGTGIT--IGEKGNIGLPGLPGEKGERGFPGIQG 380

Query: 1652 DSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGS 1711
              G+PG       G  GP GFPG+ GQKGD G PGI   PGP G             +G 
Sbjct: 381  PPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGI-SIPGPPGL------------DGQ 427

Query: 1712 RGLPGPPGQRGIKGMAGQPVYSQCD 1736
             G PG PG  G  G    P    C+
Sbjct: 428  PGAPGLPGPPGPAGPHIPPSDEICE 452



 Score =  221 bits (562), Expect = 9e-57
 Identities = 162/420 (38%), Positives = 188/420 (44%), Gaps = 88/420 (20%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGV-------------RGDTGPQGDKG 1440
            PG+PGP G  GL   +G +G KG +G +G  G PG              +GD G  GD+G
Sbjct: 209  PGLPGPKGNMGLN-FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRG 267

Query: 1441 IAGCPGAWGQKGLKGFS-GPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSR 1499
              G PG  G  G  G   G KG  G+ G  G  G++G +G PGI G  GDPG  G PG  
Sbjct: 268  PPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRD 327

Query: 1500 GAPGQYGEKGFPGDPG----NPGQ--------NNNIKGQKGSKGEQGRQGRSGQKGVQGS 1547
            G  GQ G+ G PG PG     PG         N  + G  G KGE+G  G  G  G+ G 
Sbjct: 328  GEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP 387

Query: 1548 PSSR-----------GSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQG----- 1591
            P +            G RG++G  G  G+S  PG PG  G  GA GL GP G  G     
Sbjct: 388  PGAAVMGPPGPPGFPGERGQKGDEGPPGIS-IPGPPGLDGQPGAPGLPGPPGPAGPHIPP 446

Query: 1592 -----NPGRKGEKGSQGQKGPQGSPGLMGAKGST----------------GRPGLLGKKG 1630
                  PG  G  GS G KG QG  G+ G KG T                G PGL G  G
Sbjct: 447  SDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPG 506

Query: 1631 EPGLPGDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGVKGPRG----FPGDAGQKGDIGNP 1685
              G PG  G  GQ G  G +G  GIPG  G  G  G KG  G    FPG  G KG++G+P
Sbjct: 507  SLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSP 566

Query: 1686 G---------------IPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
            G               +PG PGPKG  G    +  KGE G  G PG PG  G  G  G P
Sbjct: 567  GAPGLPGLPGTPGQDGLPGLPGPKGEPG---GITFKGERGPPGNPGLPGLPGNIGPMGPP 623



 Score =  195 bits (495), Expect = 5e-49
 Identities = 120/274 (43%), Positives = 133/274 (48%), Gaps = 21/274 (7%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG+ G  G  GL  + G+ GL G +G  G  G PGV+G  GP G  G    P   G KG 
Sbjct: 1198 PGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG----PALEGPKGN 1253

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPG---IKGEKGDPGSQGSPGSRGAPGQYGEKGF 1510
             G  GP G  G  G  GL G EG  G PG   IKGEKG+PG  G PG  G  G  G  G 
Sbjct: 1254 PGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL 1313

Query: 1511 PGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPG 1570
             G+PG PG N    G KG  G  G  G  G KG  G P   GS G EG+ GL G  G PG
Sbjct: 1314 QGNPGRPGLN----GMKGDPGLPGVPGFPGMKGPSGVP---GSAGPEGEPGLIGPPGPPG 1366

Query: 1571 NPGPTGT-------LGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRP 1623
             PGP+G         G  G+ G  G +G PG +G +G  G  GP G PG  G  G  G  
Sbjct: 1367 LPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAG 1426

Query: 1624 GLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG 1657
            G  G  G PG PG  G  G  G  G QG  G PG
Sbjct: 1427 GRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460



 Score =  159 bits (401), Expect = 4e-38
 Identities = 93/211 (44%), Positives = 106/211 (50%), Gaps = 5/211 (2%)

Query: 1516 NPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPT 1575
            +PG   +  G KG KGE+G  G  G  G+ G P   G  G  GQ+G  G+ G PG  G  
Sbjct: 33   SPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIR 92

Query: 1576 GTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLP 1635
            G  G  G  G  G  G PG  G  G QG  G  G+ G  G  GS G PGL G  G PG+P
Sbjct: 93   GPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIP 152

Query: 1636 GDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGVKGPRGFPGDAGQKGD---IGNPGIPGGP 1691
            G  G  G        G  G PGY G  G +G+ GP G PG  G  G    +G PG PG P
Sbjct: 153  GMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLP 212

Query: 1692 GPKGFRGLALTVGLKGEEGSRGLPGPPGQRG 1722
            GPKG  GL    G KGE+G +GL GPPG  G
Sbjct: 213  GPKGNMGLNFQ-GPKGEKGEQGLQGPPGPPG 242



 Score =  157 bits (398), Expect = 1e-37
 Identities = 90/227 (39%), Positives = 116/227 (51%), Gaps = 9/227 (3%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            P + GP G  G Q   G  G  G +G  G +G PG+ G+ G +G+KG  G PG  G  GL
Sbjct: 1245 PALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1304

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD 1513
            KG  GP G  G+ G  GL+G +G  G PG+ G  G  G  G PGS G  G+ G  G PG 
Sbjct: 1305 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1364

Query: 1514 PGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPG 1573
            PG PG +      KG          +G  G+ G P  +G  G +G +GL G +G PG+PG
Sbjct: 1365 PGLPGPSGQSIIIKGD---------AGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPG 1415

Query: 1574 PTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGST 1620
              G  G +G  G +G  G PG+ G +G  G  GP G  G  G  G++
Sbjct: 1416 RNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTS 1462



 Score =  105 bits (263), Expect = 4e-22
 Identities = 64/141 (45%), Positives = 71/141 (50%), Gaps = 10/141 (7%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDG---NPGVRGDTGPQGD----KGIAGCPGA 1447
            G PG  G  G   MKG  G+ GS G  GE G    PG  G  GP G     KG AG PG 
Sbjct: 1327 GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGI 1386

Query: 1448 WGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKG---EKGDPGSQGSPGSRGAPGQ 1504
             GQ GLKG  GP+G  G  G  G  G+ G +G PG  G    KGDPG  G PG+RG  G 
Sbjct: 1387 PGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGP 1446

Query: 1505 YGEKGFPGDPGNPGQNNNIKG 1525
             G  G  G PG PG ++   G
Sbjct: 1447 PGPDGLQGPPGPPGTSSVAHG 1467



 Score =  105 bits (262), Expect = 6e-22
 Identities = 61/128 (47%), Positives = 71/128 (55%), Gaps = 11/128 (8%)

Query: 1612 GLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRG 1671
            G+ G KG  G PGL   +G PGLPG  GP G  G RG++GD GIPG    G KG++GP G
Sbjct: 42   GIKGEKGERGFPGL---EGHPGLPGFPGPEGPPGPRGQKGDDGIPG--PPGPKGIRGPPG 96

Query: 1672 FPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPG------PPGQRGIKG 1725
             PG  G  G  G PG  G PGP+G  G   T G +G  GS G PG      PPG  G+KG
Sbjct: 97   LPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKG 156

Query: 1726 MAGQPVYS 1733
              G  + S
Sbjct: 157  EPGSIIMS 164



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 41/94 (43%), Positives = 46/94 (48%), Gaps = 10/94 (10%)

Query: 1644 TGQRGRQGDSGIPGY-GQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALT 1702
            +G +G +G+ G PG  G  G  G  GP G PG  GQKGD    GIPG PGPKG RG    
Sbjct: 41   SGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGD---DGIPGPPGPKGIRGPP-- 95

Query: 1703 VGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCD 1736
                G  G  G PG PG  G  G  G      C+
Sbjct: 96   ----GLPGFPGTPGLPGMPGHDGAPGPQGIPGCN 125


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score =  275 bits (704), Expect = 3e-73
 Identities = 155/350 (44%), Positives = 199/350 (56%), Gaps = 20/350 (5%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PGP G +G     G++GL+G +G +GEDG PG +GD G +GD+G  G PG  G+ G 
Sbjct: 706  PGYPGPRGVKGTS---GNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGP 762

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD 1513
            +G  G  G  G++G  G  GE+G  G PG+ G  G PG +GS G  G  G  GEKG  G 
Sbjct: 763  EGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGK 822

Query: 1514 PGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPG 1573
             G PG     +G  GS+GE+G+ G +GQ G +G     G+ G  G++GL G+ G PG PG
Sbjct: 823  TGQPGLEGE-RGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPG 881

Query: 1574 PTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPG 1633
            P G     G QG  G  G+PG++GE G QGQ GP G  G++G +G TG  G LG++G PG
Sbjct: 882  PKGP---PGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPG 938

Query: 1634 LPGDLGPVGQTGQRGRQ---GDSGIPG----YGQMGRKGVKGPRGFPGD---AGQKGDIG 1683
             PG  G  G  G  GR+   G+ G PG     G  G +G  GP+G PGD    G KGD G
Sbjct: 939  PPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKG 998

Query: 1684 NP---GIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
             P   G  G PG +G  G A  +GL G+ GS G  GP G++G +G  G P
Sbjct: 999  PPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPP 1048



 Score =  267 bits (682), Expect = 1e-70
 Identities = 161/373 (43%), Positives = 192/373 (51%), Gaps = 41/373 (10%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG  GP G RG   + G  G KG RG  G  G PG  G+ G +G +G  G  G  G+ G 
Sbjct: 541  PGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGP 600

Query: 1454 KGFSGPKGGHGD---DGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQY----- 1505
            +G  GP+G  G     G+ G+DG  G  G  G  GE G PG QG+ GS+G PG       
Sbjct: 601  RGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGT 660

Query: 1506 -GEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSS---------RGSRG 1555
             GEKG PG+PG PG    + G  G  G  G +G +G+KG QG P S         RG +G
Sbjct: 661  PGEKGPPGNPGIPG----LPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKG 716

Query: 1556 REGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGE------KGSQGQKGPQG 1609
              G RGL+G  GE G  G  G  G  GL+G QG  G PG +GE      KG  GQ G +G
Sbjct: 717  TSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEG 776

Query: 1610 SPGLMGAKGSTGRPGLLGKKGEPGLPGDL---GPVGQTGQRGRQGDSGIPGY-GQMGRKG 1665
             PG  G KG  G PGL G  G PG  G +   GP+G  G++G+ G +G PG  G+ G  G
Sbjct: 777  PPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPG 836

Query: 1666 VKGPRGFPGDAGQ---KGDIGNPGIPGGPGPKGFRGLALTVGL------KGEEGSRGLPG 1716
             +G RG PG  GQ   KGD+G  G PG PG KG  GL    G        G +G  G PG
Sbjct: 837  SRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPG 896

Query: 1717 PPGQRGIKGMAGQ 1729
             PGQRG  G  GQ
Sbjct: 897  HPGQRGELGFQGQ 909



 Score =  262 bits (670), Expect = 3e-69
 Identities = 155/363 (42%), Positives = 192/363 (52%), Gaps = 29/363 (7%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G  G  G RGL   +GS G  G  G  G DG PG +G+ GP G+ G  G  G  G +GL 
Sbjct: 593  GQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLP 652

Query: 1455 G------FSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEK 1508
            G        G KG  G+ GI GL G +G  G PG +G  G+ G+QG PGS G PG  G +
Sbjct: 653  GPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPR 712

Query: 1509 GFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGE 1568
            G  G  GN G     KG+KG  G  G +G  G KG QG P + G RG +G  G +G +G+
Sbjct: 713  GVKGTSGNRGLQGE-KGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQ 771

Query: 1569 PGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGK 1628
             G  GP G+ G +G  G  G  G PGR G KGS G  GP G  G  G  G TG+PGL G+
Sbjct: 772  AGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGE 831

Query: 1629 KGEPGLPGDLGPVGQTGQRGRQGD---SGIPGY-GQMGRKGVKGPRGF------------ 1672
            +G PG  G+ G  G TGQ G +GD    G PG  G+ G  G++GP GF            
Sbjct: 832  RGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGK 891

Query: 1673 ---PGDAGQKGDIGNPGIPGGPGPKGF---RGLALTVGLKGEEGSRGLPGPPGQRGIKGM 1726
               PG  GQ+G++G  G  G PGP G    +G    VG  GE G  G PGPPG++G+ G+
Sbjct: 892  DGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGL 951

Query: 1727 AGQ 1729
             G+
Sbjct: 952  EGR 954



 Score =  261 bits (666), Expect = 8e-69
 Identities = 152/359 (42%), Positives = 180/359 (50%), Gaps = 32/359 (8%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRG---HRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQ 1450
            PG  GP G +G     G  GL+G RG    RGE G PG  G  GP+GD G  G PG  G+
Sbjct: 808  PGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGE 867

Query: 1451 KGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGA--------- 1501
            KGL G  GP G  G  G  G  G++G  G PG +GE G  G  G PG  G          
Sbjct: 868  KGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGE 927

Query: 1502 PGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRG 1561
             G  GE+G PG PG PG+          +G  G +GR G KG  G P   G  G  G RG
Sbjct: 928  VGPLGERGPPGPPGPPGE----------QGLPGLEGREGAKGELGPPGPLGKEGPAGLRG 977

Query: 1562 LRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGE---------KGSQGQKGPQGSPG 1612
              G  G PG+PGPTG  G +G  GP G+ G+PG +G           G  G +GP G  G
Sbjct: 978  FPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAG 1037

Query: 1613 LMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGVKGPRG 1671
              G++G  G PG  GK G PG  G LGP G  G  G +GD G  G  G  G KG KG  G
Sbjct: 1038 KKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAG 1097

Query: 1672 FPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
             PG  G +G  G+PG PG  G +G RG     G KG++G RG  G  G  G++G+ G P
Sbjct: 1098 PPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPP 1156



 Score =  259 bits (661), Expect = 3e-68
 Identities = 153/358 (42%), Positives = 183/358 (51%), Gaps = 27/358 (7%)

Query: 1394 PGIPGPHGT------RGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGA 1447
            PG+ G  G       RGLQ   G  G  G  G  G DG  G+ GDTGP+GD+G  G PG 
Sbjct: 499  PGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGL 558

Query: 1448 WGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGE 1507
             G+KG +   G  G  G  G  G DGE G  G PG  G+ G+PG +G  G RG+PG  G 
Sbjct: 559  PGEKGQR---GDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGR 615

Query: 1508 KGFPGDPGNPGQNNNI-----KGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGL 1562
             G  G  G PG   N+      G  G +G  G QG  G +G+ G+P  +G  G  G  GL
Sbjct: 616  PGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGL 675

Query: 1563 RGVSGEPGNPGPTGTLGAEGLQGPQGSQGNP---------GRKGEKGSQGQKGPQGSPGL 1613
             G  G  G+PG  G  G +G QGP GS G P         G  G +G QG+KG +G  G 
Sbjct: 676  PGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGF 735

Query: 1614 MGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG-YGQMGRKGVKGPRGF 1672
             G KG  G  G  GK G PG  G+ GP G  GQ G+ G+ G PG  G+ G+ GV G  G+
Sbjct: 736  PGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGY 795

Query: 1673 PGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
            PG  G KG I   G PG  GP G +G +   G  G EG RG PG  G+RG  G  GQP
Sbjct: 796  PGRPGPKGSI---GFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQP 850



 Score =  256 bits (653), Expect = 3e-67
 Identities = 153/363 (42%), Positives = 185/363 (50%), Gaps = 35/363 (9%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG  G  G RG   + G +G  G RG  G  G PG++G  GP G+KG  G  G+ G  G 
Sbjct: 1114 PGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGA 1173

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD 1513
             G  GP+G  G +G  GL G  G  G  G KGE+GD G  G PG+ G PG  G+ G  GD
Sbjct: 1174 PGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGD 1233

Query: 1514 ---------------PGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREG 1558
                           PG  G   ++ G  G  G+ G  G  G  G+ GSP  +G  G  G
Sbjct: 1234 SGPSGAAGPPGKKGPPGEDGAKGSV-GPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVG 1292

Query: 1559 QRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKG 1618
              G  G SGEPG PGP G       +GP G  G  GR+GEKG++G+ GP G PG  G  G
Sbjct: 1293 GPGPPGASGEPGAPGPPGK------RGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMG 1346

Query: 1619 STGRPGLLGKKGEPGLPGD------LGPVGQTGQRGRQGDSGIPGY-GQMGRKGVKGPRG 1671
            + G PG +G +G  G+PG       LG  GQ G  G  G SG+PG  G  G KG KG  G
Sbjct: 1347 ARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIG 1406

Query: 1672 F------PGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKG 1725
                   PG+AG+KGD G PG+ G PGPKG  G    +G  G  G  G+ GP GQ+G KG
Sbjct: 1407 LIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKG 1466

Query: 1726 MAG 1728
              G
Sbjct: 1467 SPG 1469



 Score =  255 bits (652), Expect = 3e-67
 Identities = 147/351 (41%), Positives = 180/351 (51%), Gaps = 31/351 (8%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G+ GP G +GL    G +G  G  G  G  G PG RG  GP G +G  G PG  GQ G  
Sbjct: 1142 GVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAV 1201

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKG----- 1509
            G  G +G  GD G  G  G  G  G  G KG+ G  G+ G PG +G PG+ G KG     
Sbjct: 1202 GEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPT 1261

Query: 1510 -FPGD---PGNPGQN--NNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLR 1563
              PGD   PG+PG +  +   G+KG  G+ G  G  G  G  G+P   G RG  G  G  
Sbjct: 1262 GLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGRE 1321

Query: 1564 GVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRP 1623
            G  GE G  G  G  G  G  GP G++G PGR G +G +G  GP G PGL+GA G  G P
Sbjct: 1322 GREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPP 1381

Query: 1624 GLLGKKGEPGLPGDLGP------------VGQTGQRGRQGDSGIPGYGQMGRKGVKGPRG 1671
            G LG  G PGL GD GP            +G  G+ G +GD G+PG      +G  GP+G
Sbjct: 1382 GPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGV-----QGPPGPKG 1436

Query: 1672 FPGDAGQKGDIGNPGIPGGPGP---KGFRGLALTVGLKGEEGSRGLPGPPG 1719
             PG  G  G +G+PG PG  GP   KG +G   ++G +G+ G  G PGPPG
Sbjct: 1437 DPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPG 1487



 Score =  254 bits (650), Expect = 6e-67
 Identities = 153/347 (44%), Positives = 180/347 (51%), Gaps = 23/347 (6%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PG  G +G     G  G  G +G  G+ G PG+ G+ GP G +G  G PGA GQ G 
Sbjct: 793  PGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPG- 851

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGF---PGIKGEKGDPGSQGSPGSRGAPGQYGEKGF 1510
                 PKG  G DG  G+ GE+G  G    PG  G KG PG QG  G  G PGQ GE GF
Sbjct: 852  -----PKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGF 906

Query: 1511 PGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPG 1570
             G  G PG      G  G +G+ G  G  G++G  G P   G +G  G  G  G  GE G
Sbjct: 907  QGQTGPPGP----AGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELG 962

Query: 1571 NPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKG 1630
             PGP G  G  GL+G  G +G PG  G  G +G KGP   PG +GA GS G  G LG  G
Sbjct: 963  PPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGP---PGPVGANGSPGERGPLGPAG 1019

Query: 1631 EPGLPGDL---GPVGQTGQRGRQGDSGIPG-YGQMGRKGVKGPRGFPGDA---GQKGDIG 1683
              GLPG     GPVG  G++G +G+ G PG  G+ G  G  GP G PG A   G++GD G
Sbjct: 1020 GIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKG 1079

Query: 1684 NPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
            + G PG  G KG +G A   G  G  G  G PGPPG  G +G  G P
Sbjct: 1080 DVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPP 1126



 Score =  253 bits (645), Expect = 2e-66
 Identities = 148/360 (41%), Positives = 185/360 (51%), Gaps = 31/360 (8%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPG---------VRGDTGPQGDKGIAGC 1444
            PGIPG  G  GLQ   G  G KG  GH+G+DG PG          +G TGP G  G+ G 
Sbjct: 862  PGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGP 921

Query: 1445 PGAWGQKGL---KGFSGPKGGHGDDGIDGLDGEEGCHGF---PGIKGEKGDPGSQGSPGS 1498
             G  G+ G    +G  GP G  G+ G+ GL+G EG  G    PG  G++G  G +G PG 
Sbjct: 922  QGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGP 981

Query: 1499 RGAPGQYGEKGFPGDPGNPGQ--NNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGR 1556
            +G PG  G  G  GD G PG    N   G++G  G  G  G  GQ G +G     G +G 
Sbjct: 982  KGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGS 1041

Query: 1557 EGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGN------PGRKGEKGSQGQKGPQGS 1610
             G+RG  G +G+ G PGP G LG  G  GP G +G+      PG KG KG +G  GP G 
Sbjct: 1042 RGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQ 1101

Query: 1611 PGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPR 1670
            PG+ G  G  G PG  G +G  G PG  G  G  G RG  G  G PG      +G+ GP 
Sbjct: 1102 PGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGL-----QGLPGP- 1155

Query: 1671 GFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
              PG+ G+ GD+G+ G  G PGP+G +G   + G  G  G  G PG  G++G +G AG P
Sbjct: 1156 --PGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDP 1213



 Score =  251 bits (642), Expect = 5e-66
 Identities = 157/388 (40%), Positives = 189/388 (48%), Gaps = 56/388 (14%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGS---------------RGHRGEDGNPGVRGDTGPQGD 1438
            PG PGP G +GL  ++G +G KG                RG  G  G PG  G TG +GD
Sbjct: 937  PGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGD 996

Query: 1439 KGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPG- 1497
            KG  G  GA G  G +G  GP GG G  G  G +G  G  G  G +GE+G PG  G  G 
Sbjct: 997  KGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGI 1056

Query: 1498 --------SRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPS 1549
                      GA G  GE+G  GD G PG     KG KG KG+ G  G+ G +G  G P 
Sbjct: 1057 PGPLGPLGPPGAAGPSGEEGDKGDVGAPGH----KGSKGDKGDAGPPGQPGIRGPAGHPG 1112

Query: 1550 SRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQG 1609
              G+ G +G+RG  G+ G+ G+ G  G +G  G  G QG  G PG KGE G  G  GP G
Sbjct: 1113 PPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHG 1172

Query: 1610 SPGLMGAKGST------------GRPGLLGKKGE------------PGLPGDLGPVGQTG 1645
            +PG  G +G T            G+PG +G+KGE            PG+PG  G +G+ G
Sbjct: 1173 APGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKG 1232

Query: 1646 QRGRQGDSGIPGY----GQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLAL 1701
              G  G +G PG     G+ G KG  GP G PGD G  GD G  GI G PG KG  G   
Sbjct: 1233 DSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVG 1292

Query: 1702 TVGLKGEEGSRGLPGPPGQRGIKGMAGQ 1729
              G  G  G  G PGPPG+RG  G  G+
Sbjct: 1293 GPGPPGASGEPGAPGPPGKRGPSGHMGR 1320



 Score =  244 bits (624), Expect = 6e-64
 Identities = 147/367 (40%), Positives = 175/367 (47%), Gaps = 30/367 (8%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRG------------EDGNPGVRGDTGPQGDKGI 1441
            PG PGP G +G +   G  G  GS G RG            + G+ G  G  G +G +G 
Sbjct: 985  PGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGE 1044

Query: 1442 AGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGA 1501
             G PG  G+ G+ G  GP G  G  G  G +G++G  G PG KG KGD G  G PG  G 
Sbjct: 1045 RGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGI 1104

Query: 1502 PGQYGEKGFPGDPGNPGQNN--NIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQ 1559
             G  G  G PG  G  G+     + GQKG  G +G  G  G  G+QG P   G +G  G 
Sbjct: 1105 RGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGD 1164

Query: 1560 RGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPG---RKGEKGSQGQKGPQGSPGLMGA 1616
             G  G  G PG  GP G  G+EG  G  G  G PG    KGE+G  G  GP G+PG+ G 
Sbjct: 1165 VGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGP 1224

Query: 1617 KGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG-YGQMGRKGVKGPRGFPGD 1675
            KG  G  G  G  G  G PG  GP G+ G +G  G +G+PG  G  G  GV G  G PG+
Sbjct: 1225 KGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGE 1284

Query: 1676 AGQKGDIGNPGIPGG------------PGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGI 1723
             G  GD+G PG PG              GP G  G     G KG +G  G  GPPG+ G 
Sbjct: 1285 KGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGP 1344

Query: 1724 KGMAGQP 1730
             G  G P
Sbjct: 1345 MGARGPP 1351



 Score =  236 bits (601), Expect = 3e-61
 Identities = 147/336 (43%), Positives = 172/336 (51%), Gaps = 23/336 (6%)

Query: 1414 LKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDG 1473
            +KG  G  G  G PG  G  G  G KG  G  G  G +GL+G  GP G  G  G  G DG
Sbjct: 477  MKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADG 536

Query: 1474 EEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQ 1533
              G  G  G KG++G  G  G PG +G  G +G  G PG PG  G+    +G +G  G  
Sbjct: 537  ARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGE----RGAEGPPGPT 592

Query: 1534 GRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNP 1593
            G+ G  G +G+ G   S G  GR G  G+ G  G  GN GP G  G  G QG  GSQG P
Sbjct: 593  GQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLP 652

Query: 1594 GRKGEKGSQGQKGPQGSPGLMGAKGS------TGRPGLLGKKGEPGLPGDLGPVGQTGQR 1647
            G +G  G+ G+KGP G+PG+ G  GS       G  G  G+KG  G PG  GP G  G R
Sbjct: 653  GPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPR 712

Query: 1648 GRQGDSGIPG-YGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPG-----GP-GPKGFRGLA 1700
            G +G SG  G  G+ G KG  G  GF GD G KGD G PG PG     GP GPKG  G A
Sbjct: 713  GVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQA 772

Query: 1701 ------LTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
                   + G KG+ G  GLPG PG+ G KG  G P
Sbjct: 773  GEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFP 808



 Score =  235 bits (599), Expect = 5e-61
 Identities = 151/404 (37%), Positives = 185/404 (45%), Gaps = 74/404 (18%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGI------------ 1441
            PG PGP G  G     G  G  G  G  G  G PG+ G  G +G  G             
Sbjct: 394  PGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGS 453

Query: 1442 ------------------------------AGCPGAWGQKGLKGFSGPKGGHGDDGIDGL 1471
                                           G  G  G  GL G  G KG  G +G  G 
Sbjct: 454  FKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGP 513

Query: 1472 DGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKG 1531
             G +G HG PG  G+ G PG+ G+ G  G  G  G++GF G PG PG+    KGQ+G  G
Sbjct: 514  RGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGE----KGQRGDFG 569

Query: 1532 EQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQG 1591
              G+ G  G+ G +G+    G  G+ G+ G RG+ G  G+PGPTG  G  G+ G  G++G
Sbjct: 570  HVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKG 629

Query: 1592 N---------PGRKGEKGSQGQKGPQ---GSPGLMGAKGSTGRPGLLGKKGEPGLPGDLG 1639
            N         PG++G  GSQG  GPQ   G+PG  G  G+ G PGL G  G  G PG  G
Sbjct: 630  NVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEG 689

Query: 1640 PVGQTGQRGRQGDSGIPGY-GQMGRKGVKGPRGFPGDAGQKGDIGNPGI----------- 1687
            P G+ G +G  G +G PGY G  G KG  G RG  G+ G+KG+ G PG            
Sbjct: 690  PTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQG 749

Query: 1688 -PGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
             PG PGP+G  G     G KG+ G  G  GPPG  G KG  G P
Sbjct: 750  KPGAPGPRGEDG---PEGPKGQAGQAGEEGPPGSAGEKGKLGVP 790



 Score =  228 bits (581), Expect = 6e-59
 Identities = 139/329 (42%), Positives = 159/329 (48%), Gaps = 29/329 (8%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PGP G +G    +G+ GL G  G  G  G  G RGD G  G  G  G PG  G  G K
Sbjct: 1172 GAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEK 1231

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDP 1514
            G SGP G  G  G  G  GE+G  G  G  G  GD G  G PG  G  G  GEKG PGD 
Sbjct: 1232 GDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDV 1291

Query: 1515 GNPGQNN--------NIKGQKGSKGEQGRQGRSGQKGVQGSPS------------SRGSR 1554
            G PG              G++G  G  GR+GR G+KG +G P             +RG  
Sbjct: 1292 GGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPP 1351

Query: 1555 GREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLM 1614
            GR G  GLRG+ G  G PG  G  G  G  GP G  G PG KG+ G +G+KG  G  GL+
Sbjct: 1352 GRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLI 1411

Query: 1615 GAKGSTGRPG---LLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRG 1671
            G  G  G  G   L G +G PG  GD GP G  G  G  G  G+ G   +G+KG KG   
Sbjct: 1412 GPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAG--PLGQKGSKGS-- 1467

Query: 1672 FPGDAGQKGDIGNPGIPGGPG-PKGFRGL 1699
             PG  G +GD G  G PG PG P    GL
Sbjct: 1468 -PGSMGPRGDTGPAGPPGPPGAPAELHGL 1495



 Score =  196 bits (498), Expect = 2e-49
 Identities = 124/316 (39%), Positives = 148/316 (46%), Gaps = 39/316 (12%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG+PG  G  G    KG +G  G  G  G  G PG +GD G +GD G +G  G  G+KG 
Sbjct: 1189 PGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGP 1248

Query: 1454 KGFSGPKGG------------HGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGA 1501
             G  G KG              GD G+ G+DG  G  G PG  G  G PG+ G PG+ G 
Sbjct: 1249 PGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGP 1308

Query: 1502 PG---------------QYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQG 1546
            PG               + G KG PG  G PG+   + G +G  G  G +G  G  G  G
Sbjct: 1309 PGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPM-GARGPPGRVGPEGLRGIPGPVG 1367

Query: 1547 SPSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKG 1606
             P   G+ G+ G  G  G SG PG  G TG  G +G  G  G  G PG  GEKG QG  G
Sbjct: 1368 EPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPG 1427

Query: 1607 PQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGV 1666
             QG P   G KG  G PG +G  G PG PG  GP+GQ G +G          G MG +G 
Sbjct: 1428 VQGPP---GPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSP--------GSMGPRGD 1476

Query: 1667 KGPRGFPGDAGQKGDI 1682
             GP G PG  G   ++
Sbjct: 1477 TGPAGPPGPPGAPAEL 1492



 Score =  187 bits (474), Expect = 1e-46
 Identities = 136/367 (37%), Positives = 165/367 (44%), Gaps = 77/367 (20%)

Query: 1419 GHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCH 1478
            G +G  G P V  + G Q +    G PGA G +G+ G SGP G  G  G  G  G  G  
Sbjct: 373  GEKGAKGEPAVI-EKGQQFE----GPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLP 427

Query: 1479 GFPGIKGEKGDPGS-------------QGSPGS-----------------RGAPGQYGEK 1508
            G PGI G +G PG+             +G P S                 +G PG  G  
Sbjct: 428  GIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLT 487

Query: 1509 GFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGE 1568
            G PG  G PG         G KGE+G +G  G +G+QG     G  G+ G+ G  G  G 
Sbjct: 488  GRPGPVGLPGH-------PGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGL 540

Query: 1569 PGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGK 1628
            PG+ GP G  G +GL G       PG KG++G  G  G  G PG  G +G+ G PG  G+
Sbjct: 541  PGDTGPKGDRGFDGLPGL------PGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQ 594

Query: 1629 KGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGD------- 1681
             GEPG  G LGP G  G  GR G +GI G    G KG  GP G PG  GQ+G+       
Sbjct: 595  AGEPGPRGLLGPRGSPGPTGRPGVTGIDG--APGAKGNVGPPGEPGPPGQQGNHGSQGLP 652

Query: 1682 -----IGNPGIPGGPGPKGFRGLALT---------------VGLKGEEGSRGLPGPPGQR 1721
                 IG PG  G PG  G  GL  +                G +G  GS G PG PG R
Sbjct: 653  GPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPR 712

Query: 1722 GIKGMAG 1728
            G+KG +G
Sbjct: 713  GVKGTSG 719



 Score =  106 bits (265), Expect = 3e-22
 Identities = 62/149 (41%), Positives = 78/149 (52%), Gaps = 15/149 (10%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGN------PGVRGDTGPQGDKG------I 1441
            PG  GP G RG+    G  GL G+ G  G  G       PG++GDTGP+G+KG      +
Sbjct: 1351 PGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGL 1410

Query: 1442 AGCPGAWGQKG---LKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGS 1498
             G PG  G+KG   L G  GP G  GD G  G  G  G  G PG+ G  G  GS+GSPGS
Sbjct: 1411 IGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGS 1470

Query: 1499 RGAPGQYGEKGFPGDPGNPGQNNNIKGQK 1527
             G  G  G  G PG PG P + + ++ ++
Sbjct: 1471 MGPRGDTGPAGPPGPPGAPAELHGLRRRR 1499



 Score = 82.8 bits (203), Expect = 4e-15
 Identities = 71/211 (33%), Positives = 88/211 (41%), Gaps = 42/211 (19%)

Query: 1539 SGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGE 1598
            +G+KG +G P+       +GQ+      G PG PGP         QG  G  G PG  G 
Sbjct: 372  AGEKGAKGEPAVI----EKGQQ----FEGPPGAPGP---------QGVVGPSGPPGPPGF 414

Query: 1599 KGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDL-GPVGQTGQRGRQGDSGIPG 1657
             G  G  GP G PG+ G  G  G PG +         G   GP     Q   Q       
Sbjct: 415  PGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVL---- 470

Query: 1658 YGQMGRKGVKGPRGFPGDAGQKGDIGNPGIP------GGPGPKGFRGL---------ALT 1702
              Q  +  +KGP G  G  G+ G +G PG P      G  GP+G RGL            
Sbjct: 471  --QQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGK 528

Query: 1703 VGLKGEEGSRGLP---GPPGQRGIKGMAGQP 1730
            +G  G +G+RGLP   GP G RG  G+ G P
Sbjct: 529  MGRPGADGARGLPGDTGPKGDRGFDGLPGLP 559



 Score = 40.8 bits (94), Expect = 0.017
 Identities = 30/78 (38%), Positives = 34/78 (43%), Gaps = 20/78 (25%)

Query: 1672 FPGDAGQKGDIGNPGI----------PGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQR 1721
            FPG AG+KG  G P +          PG PGP+G         + G  G  G PG PG  
Sbjct: 369  FPG-AGEKGAKGEPAVIEKGQQFEGPPGAPGPQG---------VVGPSGPPGPPGFPGDP 418

Query: 1722 GIKGMAGQPVYSQCDLIR 1739
            G  G AG P     D IR
Sbjct: 419  GPPGPAGLPGIPGIDGIR 436


>gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo
            sapiens]
          Length = 921

 Score =  274 bits (701), Expect = 7e-73
 Identities = 161/366 (43%), Positives = 196/366 (53%), Gaps = 21/366 (5%)

Query: 1393 CPGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKG 1452
            CP  PG  G  GL  M+G +G KG  G  G  G+ G  GD G  G+ G  G PGA G +G
Sbjct: 415  CP--PGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRG 472

Query: 1453 LKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPG 1512
            + G  G KG  G  G+DG  G +G  G PG +G++G PG  G  G RGA G  G  G PG
Sbjct: 473  ITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPG 532

Query: 1513 ---DPGNPGQN--NNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSG 1567
               D G PG +  + I G  G+KGE G+ G  G  G+QG P   G  G +G  G +G +G
Sbjct: 533  PKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTG 592

Query: 1568 EPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLG 1627
             PG PG  G  G  G QGP G  G  G +G  GS+G+ GP GSPGL G  GS G PGL G
Sbjct: 593  APGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPG 652

Query: 1628 KKGEPGLP---GDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGN 1684
              G PGLP   GD G VG+ G +G QG SG    G+ G +G  G  G P   G KG  GN
Sbjct: 653  LPGPPGLPGMKGDRGVVGEPGPKGEQGASG--EEGEAGERGELGDIGLP---GPKGSAGN 707

Query: 1685 PGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCD------LI 1738
            PG PG  GP+G RGL    G +G  G RG+ G  G  G+ G+ G P  +  D       +
Sbjct: 708  PGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCM 767

Query: 1739 RFLREH 1744
            R ++EH
Sbjct: 768  RVIQEH 773



 Score =  253 bits (645), Expect = 2e-66
 Identities = 158/386 (40%), Positives = 196/386 (50%), Gaps = 54/386 (13%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTG---------------PQGD 1438
            PG PGP GT GL    G  G  G  G RG  G PG  G  G               P G 
Sbjct: 360  PGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGR 419

Query: 1439 KGIAGCPGAWGQKGLKGFSGPKG--GH-GDDGIDGLDGEEGCHGFP---GIKGEKGDPGS 1492
             G  G PG  G KG KG  G  G  GH G++G  G  GE G  G P   G++G  G  G 
Sbjct: 420  SGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGD 479

Query: 1493 QGSPGSRGAPGQYGEKGFPGDPGNPGQNN--NIKGQKGSKGEQGRQGRSGQKGVQGSPSS 1550
            +G  G+RG  G+ G +G PG PG+ GQ       G KG +G +G +G  G  G +G    
Sbjct: 480  KGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGL 539

Query: 1551 RGSRGREGQRGLRGVSGEPGNPGPTGTL------------GAEGLQGPQGSQGNPGRKGE 1598
             G  GR+G  G+ G  GEPG PGP G              GA+G+ G +GS G PG+ G+
Sbjct: 540  PGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQ 599

Query: 1599 KGSQGQKGPQGSPGLMGAKGSTGRPGL---LGKKGEPGLPGDLGPVGQTGQRGRQGDSGI 1655
             G+ G+ G QG PG +G +G  G PG    LG  G PGLPG LG +G  G  G  G  G+
Sbjct: 600  MGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGL 659

Query: 1656 PG-------YGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGE 1708
            PG        G+ G KG +G  G  G+AG++G++G+ G+   PGPKG  G     GL+G 
Sbjct: 660  PGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGL---PGPKGSAGNPGEPGLRGP 716

Query: 1709 EGSRGLP------GPPGQRGIKGMAG 1728
            EGSRGLP      GPPG RG++G  G
Sbjct: 717  EGSRGLPGVEGPRGPPGPRGVQGEQG 742



 Score =  248 bits (634), Expect = 4e-65
 Identities = 159/404 (39%), Positives = 191/404 (47%), Gaps = 71/404 (17%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G  GP G +GL+ + G  G KG +G RG DG PG +G  G  GD+G  G PG  G KG +
Sbjct: 460  GAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDR 519

Query: 1455 GFSGPKG------GHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGS---------PGSR 1499
            G  G +G        GD G+ G+DG +G  G PG KGE G PG  G          PG  
Sbjct: 520  GAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIP 579

Query: 1500 GAPGQYGEKGFPGDPGNPGQNNNI--------KGQKGSKGEQGRQGRSGQKGVQGSPSSR 1551
            GA G  GEKG  G PG PGQ  N          G+ G +G QG  G  G+ G  GSP   
Sbjct: 580  GAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLP 639

Query: 1552 GSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSP 1611
            G  G  G  GL G+ G PG PG  G  G  G  GP+G QG  G +GE G +G+ G  G P
Sbjct: 640  GKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLP 699

Query: 1612 GLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGD---SGIPGY---------- 1658
            G  G+ G+ G PGL G +G  GLPG  GP G  G RG QG+   +G+PG           
Sbjct: 700  GPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTD 759

Query: 1659 ------------------------------GQMGRKGVKGPRGFPGDAGQKGDIGNPGIP 1688
                                          G  GR G  GP G PG+ G  G +G  G+P
Sbjct: 760  QHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLP 819

Query: 1689 GGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQ--RGIKGMAGQP 1730
            G  GP G  GL    G KG+ G +G  GPPG+   G+ G  G P
Sbjct: 820  GIKGPPGALGLR---GPKGDLGEKGERGPPGRGPNGLPGAIGLP 860



 Score =  244 bits (622), Expect = 1e-63
 Identities = 153/384 (39%), Positives = 182/384 (47%), Gaps = 50/384 (13%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG  GP G  G   + G  G+ G RG +G  G PG  G+ G  G  G  G PGA    GL
Sbjct: 271  PGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGA---DGL 327

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFP--GIKGEKGDPGSQGSPGSRGAPGQYGE---K 1508
             G  G  G  G  G  G  G  G  GFP  GI G  G PG+ G PG  G  G  G+   +
Sbjct: 328  TGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRR 387

Query: 1509 GFPGDPGNPGQNNNI-----------------------------KGQKGSKGEQGRQGRS 1539
            G PG PG PG    I                             KG KG  GE GRQG  
Sbjct: 388  GPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHK 447

Query: 1540 GQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEK 1599
            G++G QG     G++G  G +GLRG++G  G+ G  G  G +G  GPQG  G PG +G++
Sbjct: 448  GEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQR 507

Query: 1600 GSQGQKGPQGS---------PGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQ 1650
            G  G+ GP+G          PGL G KG TG PG+ G+ G PG+PG  G  G+ G  G  
Sbjct: 508  GPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDA 567

Query: 1651 GDSGIPGY----GQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLK 1706
            G  G+PG     G  G  G KG  G PG  GQ G+ G PG  G PG  G RG     G +
Sbjct: 568  GLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSR 627

Query: 1707 GEEGSRGLPGPPGQRGIKGMAGQP 1730
            GE G  G PG PG+ G  G  G P
Sbjct: 628  GELGPVGSPGLPGKLGSLGSPGLP 651



 Score =  234 bits (598), Expect = 6e-61
 Identities = 145/373 (38%), Positives = 180/373 (48%), Gaps = 42/373 (11%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG+PGP G  GL  + G  G+ G  G +GE G PG  GD G QG  G+ G PGA G  G 
Sbjct: 528  PGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGE 587

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGS---PGSRGAPGQYGEKGF 1510
            KG +G  G  G  G  G  G++G  G  G +G +G PGS+G     GS G PG+ G  G 
Sbjct: 588  KGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGS 647

Query: 1511 PGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPG 1570
            PG PG PG    + G KG +G  G  G  G++G  G     G RG  G  GL G  G  G
Sbjct: 648  PGLPGLPGPPG-LPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAG 706

Query: 1571 NPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKG------------ 1618
            NPG  G  G EG +G  G +G  G  G +G QG++G  G PG+ G  G            
Sbjct: 707  NPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVC 766

Query: 1619 -------------STGRP--GLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGY-GQMG 1662
                         S  RP  G  G  G PG PG  GP G+ G  G+ G  G+PG  G  G
Sbjct: 767  MRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPG 826

Query: 1663 RKGVKGPRGFPGDAGQKGDIGNP--------GIPGGPGPKGF--RGLALTVGLKGEEGSR 1712
              G++GP+G  G+ G++G  G          G+PG PGP  +   G     G  G  G  
Sbjct: 827  ALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIP 886

Query: 1713 GLPGPPGQRGIKG 1725
            G+PGPPG  G+ G
Sbjct: 887  GVPGPPGPPGLPG 899



 Score =  217 bits (553), Expect = 1e-55
 Identities = 135/321 (42%), Positives = 160/321 (49%), Gaps = 24/321 (7%)

Query: 1423 EDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPG 1482
            E G PG +G  GP G  G+ G  G  G +G KG  GP G  G+ G  G  G+ G  G  G
Sbjct: 267  ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 326

Query: 1483 IKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD--PGNPGQNNNIKGQKGSKGEQGRQGRSG 1540
            + G  G PGS GS G +G PG  G +GFPG   PG PG      G  G  GE GR G  G
Sbjct: 327  LTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGP----PGTAGLPGELGRVGPVG 382

Query: 1541 QKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPG--PTGTLGAEGLQGPQGSQGNPGRKGE 1598
              G +G P   G  G  G  G     G+P  P   P G  G  GL G +G +G  G  GE
Sbjct: 383  DPGRRGPPGPPGPPGPRGTIGFH--DGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGE 440

Query: 1599 KGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGY 1658
             G QG KG +G  G +G  G+ G PG  G +G  G+ GD G  G  G  G  G  G+P  
Sbjct: 441  PGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLP-- 498

Query: 1659 GQMGRKGVKGPRGFPGDAGQKGDIGNP---GIPGGPGPKGFRGLALT------VGLKGEE 1709
               G  G +G RG PG+AG KGD G     GIPG PGPKG  GL          G+ G +
Sbjct: 499  ---GAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTK 555

Query: 1710 GSRGLPGPPGQRGIKGMAGQP 1730
            G  G PGPPG  G++G+ G P
Sbjct: 556  GEPGKPGPPGDAGLQGLPGVP 576



 Score =  162 bits (410), Expect = 4e-39
 Identities = 97/242 (40%), Positives = 120/242 (49%), Gaps = 30/242 (12%)

Query: 1517 PGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTG 1576
            P Q  + +G  G +G  G  G  G  G+ G    RG +G  G  G  G  G+PG PG  G
Sbjct: 261  PSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPG 320

Query: 1577 TLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGL-----MGAKGSTGRPGLLGKKGE 1631
            T GA+GL GP GS G+ G KG+KG  G  G +G PG       G  G+ G PG LG+ G 
Sbjct: 321  TPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGP 380

Query: 1632 PGLPGDLGPVGQTGQRGRQGD------------------SGIPGY-GQMGRKGVKGPRGF 1672
             G PG  GP G  G  G +G                   SG PG  G  G KG KG  G 
Sbjct: 381  VGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGE 440

Query: 1673 P------GDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGM 1726
            P      G+ G +G++G  G  G PG +G RG+   VG KGE+G+RGL G PG +G+ G 
Sbjct: 441  PGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGA 500

Query: 1727 AG 1728
             G
Sbjct: 501  PG 502


>gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo
            sapiens]
          Length = 678

 Score =  274 bits (701), Expect = 7e-73
 Identities = 161/366 (43%), Positives = 196/366 (53%), Gaps = 21/366 (5%)

Query: 1393 CPGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKG 1452
            CP  PG  G  GL  M+G +G KG  G  G  G+ G  GD G  G+ G  G PGA G +G
Sbjct: 172  CP--PGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRG 229

Query: 1453 LKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPG 1512
            + G  G KG  G  G+DG  G +G  G PG +G++G PG  G  G RGA G  G  G PG
Sbjct: 230  ITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPG 289

Query: 1513 ---DPGNPGQN--NNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSG 1567
               D G PG +  + I G  G+KGE G+ G  G  G+QG P   G  G +G  G +G +G
Sbjct: 290  PKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTG 349

Query: 1568 EPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLG 1627
             PG PG  G  G  G QGP G  G  G +G  GS+G+ GP GSPGL G  GS G PGL G
Sbjct: 350  APGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPG 409

Query: 1628 KKGEPGLP---GDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGN 1684
              G PGLP   GD G VG+ G +G QG SG    G+ G +G  G  G P   G KG  GN
Sbjct: 410  LPGPPGLPGMKGDRGVVGEPGPKGEQGASG--EEGEAGERGELGDIGLP---GPKGSAGN 464

Query: 1685 PGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCD------LI 1738
            PG PG  GP+G RGL    G +G  G RG+ G  G  G+ G+ G P  +  D       +
Sbjct: 465  PGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCM 524

Query: 1739 RFLREH 1744
            R ++EH
Sbjct: 525  RVIQEH 530



 Score =  253 bits (645), Expect = 2e-66
 Identities = 158/386 (40%), Positives = 196/386 (50%), Gaps = 54/386 (13%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTG---------------PQGD 1438
            PG PGP GT GL    G  G  G  G RG  G PG  G  G               P G 
Sbjct: 117  PGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGR 176

Query: 1439 KGIAGCPGAWGQKGLKGFSGPKG--GH-GDDGIDGLDGEEGCHGFP---GIKGEKGDPGS 1492
             G  G PG  G KG KG  G  G  GH G++G  G  GE G  G P   G++G  G  G 
Sbjct: 177  SGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGD 236

Query: 1493 QGSPGSRGAPGQYGEKGFPGDPGNPGQNN--NIKGQKGSKGEQGRQGRSGQKGVQGSPSS 1550
            +G  G+RG  G+ G +G PG PG+ GQ       G KG +G +G +G  G  G +G    
Sbjct: 237  KGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGL 296

Query: 1551 RGSRGREGQRGLRGVSGEPGNPGPTGTL------------GAEGLQGPQGSQGNPGRKGE 1598
             G  GR+G  G+ G  GEPG PGP G              GA+G+ G +GS G PG+ G+
Sbjct: 297  PGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQ 356

Query: 1599 KGSQGQKGPQGSPGLMGAKGSTGRPGL---LGKKGEPGLPGDLGPVGQTGQRGRQGDSGI 1655
             G+ G+ G QG PG +G +G  G PG    LG  G PGLPG LG +G  G  G  G  G+
Sbjct: 357  MGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGL 416

Query: 1656 PG-------YGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGE 1708
            PG        G+ G KG +G  G  G+AG++G++G+ G+   PGPKG  G     GL+G 
Sbjct: 417  PGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGL---PGPKGSAGNPGEPGLRGP 473

Query: 1709 EGSRGLP------GPPGQRGIKGMAG 1728
            EGSRGLP      GPPG RG++G  G
Sbjct: 474  EGSRGLPGVEGPRGPPGPRGVQGEQG 499



 Score =  248 bits (634), Expect = 4e-65
 Identities = 159/404 (39%), Positives = 191/404 (47%), Gaps = 71/404 (17%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G  GP G +GL+ + G  G KG +G RG DG PG +G  G  GD+G  G PG  G KG +
Sbjct: 217  GAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDR 276

Query: 1455 GFSGPKG------GHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGS---------PGSR 1499
            G  G +G        GD G+ G+DG +G  G PG KGE G PG  G          PG  
Sbjct: 277  GAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIP 336

Query: 1500 GAPGQYGEKGFPGDPGNPGQNNNI--------KGQKGSKGEQGRQGRSGQKGVQGSPSSR 1551
            GA G  GEKG  G PG PGQ  N          G+ G +G QG  G  G+ G  GSP   
Sbjct: 337  GAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLP 396

Query: 1552 GSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSP 1611
            G  G  G  GL G+ G PG PG  G  G  G  GP+G QG  G +GE G +G+ G  G P
Sbjct: 397  GKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLP 456

Query: 1612 GLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGD---SGIPGY---------- 1658
            G  G+ G+ G PGL G +G  GLPG  GP G  G RG QG+   +G+PG           
Sbjct: 457  GPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTD 516

Query: 1659 ------------------------------GQMGRKGVKGPRGFPGDAGQKGDIGNPGIP 1688
                                          G  GR G  GP G PG+ G  G +G  G+P
Sbjct: 517  QHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLP 576

Query: 1689 GGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQ--RGIKGMAGQP 1730
            G  GP G  GL    G KG+ G +G  GPPG+   G+ G  G P
Sbjct: 577  GIKGPPGALGLR---GPKGDLGEKGERGPPGRGPNGLPGAIGLP 617



 Score =  244 bits (623), Expect = 8e-64
 Identities = 153/390 (39%), Positives = 183/390 (46%), Gaps = 50/390 (12%)

Query: 1391 CKCPGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQ 1450
            C C    GP G +G     G  G+ G  G  G+ G  G  G  GP G+ G  G PG  G 
Sbjct: 19   CLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGT 78

Query: 1451 KGLKGFSGPKGGHGDDGIDGLDGE---EGCHGFP--GIKGEKGDPGSQGSPGSRGAPGQY 1505
             G  G +GP G  G  G  G  GE    G  GFP  GI G  G PG+ G PG  G  G  
Sbjct: 79   PGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPV 138

Query: 1506 GE---KGFPGDPGNPGQNNNI-----------------------------KGQKGSKGEQ 1533
            G+   +G PG PG PG    I                             KG KG  GE 
Sbjct: 139  GDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEP 198

Query: 1534 GRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNP 1593
            GRQG  G++G QG     G++G  G +GLRG++G  G+ G  G  G +G  GPQG  G P
Sbjct: 199  GRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAP 258

Query: 1594 GRKGEKGSQGQKGPQGS---------PGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQT 1644
            G +G++G  G+ GP+G          PGL G KG TG PG+ G+ G PG+PG  G  G+ 
Sbjct: 259  GDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKP 318

Query: 1645 GQRGRQGDSGIPGY----GQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLA 1700
            G  G  G  G+PG     G  G  G KG  G PG  GQ G+ G PG  G PG  G RG  
Sbjct: 319  GPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQ 378

Query: 1701 LTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
               G +GE G  G PG PG+ G  G  G P
Sbjct: 379  GLPGSRGELGPVGSPGLPGKLGSLGSPGLP 408



 Score =  234 bits (598), Expect = 6e-61
 Identities = 145/373 (38%), Positives = 180/373 (48%), Gaps = 42/373 (11%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG+PGP G  GL  + G  G+ G  G +GE G PG  GD G QG  G+ G PGA G  G 
Sbjct: 285  PGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGE 344

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGS---PGSRGAPGQYGEKGF 1510
            KG +G  G  G  G  G  G++G  G  G +G +G PGS+G     GS G PG+ G  G 
Sbjct: 345  KGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGS 404

Query: 1511 PGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPG 1570
            PG PG PG    + G KG +G  G  G  G++G  G     G RG  G  GL G  G  G
Sbjct: 405  PGLPGLPGPPG-LPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAG 463

Query: 1571 NPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKG------------ 1618
            NPG  G  G EG +G  G +G  G  G +G QG++G  G PG+ G  G            
Sbjct: 464  NPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVC 523

Query: 1619 -------------STGRP--GLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGY-GQMG 1662
                         S  RP  G  G  G PG PG  GP G+ G  G+ G  G+PG  G  G
Sbjct: 524  MRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPG 583

Query: 1663 RKGVKGPRGFPGDAGQKGDIGNP--------GIPGGPGPKGF--RGLALTVGLKGEEGSR 1712
              G++GP+G  G+ G++G  G          G+PG PGP  +   G     G  G  G  
Sbjct: 584  ALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIP 643

Query: 1713 GLPGPPGQRGIKG 1725
            G+PGPPG  G+ G
Sbjct: 644  GVPGPPGPPGLPG 656



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 55/146 (37%), Positives = 64/146 (43%), Gaps = 30/146 (20%)

Query: 1613 LMGAKGSTGRPGLLGKKGEPGLP------------GDLGPVGQTGQRGRQGDSGIPGY-- 1658
            L+G      + G  G++G PG P            GD GP G  G  G  G+ G PG   
Sbjct: 15   LLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPG 74

Query: 1659 --GQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGG-----------PGPKGFRGL---ALT 1702
              G  G  G+ GP G PG  G KG  G PG+PG            PGP G  GL      
Sbjct: 75   KPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGR 134

Query: 1703 VGLKGEEGSRGLPGPPGQRGIKGMAG 1728
            VG  G+ G RG PGPPG  G +G  G
Sbjct: 135  VGPVGDPGRRGPPGPPGPPGPRGTIG 160



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 32/85 (37%), Positives = 38/85 (44%), Gaps = 6/85 (7%)

Query: 1652 DSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIP------GGPGPKGFRGLALTVGL 1705
            D G  G   +G       RG PG+ G  G  G PG+P      G  GPKG  G     G 
Sbjct: 7    DRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGE 66

Query: 1706 KGEEGSRGLPGPPGQRGIKGMAGQP 1730
             G+ G+ G PG PG  G+ G  G P
Sbjct: 67   PGKPGAPGKPGTPGADGLTGPDGSP 91


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score =  274 bits (700), Expect = 9e-73
 Identities = 178/459 (38%), Positives = 234/459 (50%), Gaps = 70/459 (15%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G+ GP G  G Q  KG  G KG++G++G+ G  GV GD GP G  G  G  G+ G  G  
Sbjct: 1237 GVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAP 1296

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGS-------PGSRGAPGQYGE 1507
            G  G +G  G  G DG  G  G  G PG KGEKG+ G  G        PG RG  G  G+
Sbjct: 1297 GRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGD 1356

Query: 1508 KGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSG 1567
            +G PGDPG PGQ    +G +G +G+ G+QG+ G  G +G P  +GS+G EG +G +G +G
Sbjct: 1357 RGEPGDPGYPGQ----EGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAG 1412

Query: 1568 EPGN---------PGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKG 1618
             PG          PGP G +G +GL+G  G  G PGR G+ G QG++G  G PG MG  G
Sbjct: 1413 APGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAG 1472

Query: 1619 STGRPGLLGK---------KGEPGLPGDLGPVGQTGQRGRQG---------------DSG 1654
              G PG+ G          KGE GLPG LGP G+ G  GR G               DSG
Sbjct: 1473 KRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSG 1532

Query: 1655 IPGY-------------GQMGRKGVKGPRGFPGDAGQKGDIGNPGI--PGG-PGPKGFRG 1698
              G+             G +G KG++GPRG PG  G++G +G  GI  P G PGPKG +G
Sbjct: 1533 EMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKG 1592

Query: 1699 LALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCD----LIRFLREHSPCWKEKCPA 1754
               + G  G +G RG PGP G+ G  G  G P+  Q D      +   + S   + +  +
Sbjct: 1593 ---SRGDWGLQGPRGPPGPRGRPGPPGPPGGPIQLQQDDLGAAFQTWMDTSGALRPESYS 1649

Query: 1755 YPTELVFALDNSYDVTEESFNKTRDIITSIVNDLNIREN 1793
            YP  LV  LD   ++  ++ +   ++I SI   L  +EN
Sbjct: 1650 YPDRLV--LDQGGEIF-KTLHYLSNLIQSIKTPLGTKEN 1685



 Score =  264 bits (674), Expect = 9e-70
 Identities = 161/408 (39%), Positives = 203/408 (49%), Gaps = 72/408 (17%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGN---PGVRGDTGPQGDKGIAGCPGAWGQ 1450
            PG+PGP G+ G   M G  G  G  G +G  G+   PG+RG  G +G +G  G  G  G 
Sbjct: 1020 PGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGS 1079

Query: 1451 KGLKGFSGPKGGHGDDGIDGLDGEEG---CHGFPGIKGEKGDPGSQGSPGS--------- 1498
            +GLKG  GP+G  G  G  G+ GE G     GFPGI G  G PG++G PG          
Sbjct: 1080 RGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGP 1139

Query: 1499 ---------RGAPGQYGEKGFPGDPG---------NPGQNNNI--KGQKGSKGEQGRQGR 1538
                     +G PG  GE G PG+ G          PG+   I  +G+ G +G+ G  G 
Sbjct: 1140 IGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGP 1199

Query: 1539 SGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGE 1598
             G KG +G P   G  G +GQ GL G  G PG PG TG  G EG  G QG +G  G KG 
Sbjct: 1200 DGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGA 1259

Query: 1599 KGSQGQ---------KGPQGSPGLMGAKGS---TGRPGLLGKKGEPGLP---------GD 1637
            KG QGQ          GP G+PG  G++GS   TG PG +G +GEPGL          G 
Sbjct: 1260 KGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGP 1319

Query: 1638 LGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNP------------ 1685
            LGP G  G++G QG+ G    G  G  G +GP G  GD G+ GD G P            
Sbjct: 1320 LGPPGPKGEKGEQGEDG-KAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKP 1378

Query: 1686 ---GIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
               G PG PGP+G+ G   + G +G +G +G  G PG+RG++G+ G P
Sbjct: 1379 GQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLP 1426



 Score =  260 bits (665), Expect = 1e-68
 Identities = 165/416 (39%), Positives = 197/416 (47%), Gaps = 81/416 (19%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGA---WGQ 1450
            PG PGP G  G     G  G +G +G  G  G PG RG  GP+GD+G  G PGA    GQ
Sbjct: 903  PGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQ 962

Query: 1451 KGLKGF------SGPKGGHGDDGIDGLDGEEGCHGF------PGIKGEKGDPGSQGSPGS 1498
             G KGF       G KG  GD G  G  GE+G  GF      PGI GEKGD G  G PG 
Sbjct: 963  PGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGV 1022

Query: 1499 RGAPGQYGEKGFPGDPGNPGQNN--------------NIKGQKGSKGEQGRQGRSGQKGV 1544
             G  G  G  G PG  G PG+                  KG++G +G  G  G  G +G+
Sbjct: 1023 PGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGL 1082

Query: 1545 QGSPSSRGSRGREGQRGLRGVSGE------PGNPGPTGTLGAEGL------QGPQGSQGN 1592
            +G P  +G  GR GQ+G+ G  G       PG PGP+G  G +GL      QGPQG  G 
Sbjct: 1083 KGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGP 1142

Query: 1593 PGRKGEKGSQGQKGPQGSPGLMGAKG------STGRPGLLGKKGEPGLPGDLGPV----- 1641
            PG  G KG  G  G  G PG  G KG      + G  GL+G++GEPGL GD GP+     
Sbjct: 1143 PGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGL 1202

Query: 1642 -------------GQTGQRGRQGDSGIPG----------------YGQMGRKGVKGPRGF 1672
                         G+ GQ G  G+ G PG                 G+ GR G KG +G+
Sbjct: 1203 KGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGY 1262

Query: 1673 PGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAG 1728
             G  G+ G  G+PG PG PGPKG RG     G  G  G++G PG  G  G KG+ G
Sbjct: 1263 QGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVG 1318



 Score =  255 bits (652), Expect = 3e-67
 Identities = 155/392 (39%), Positives = 197/392 (50%), Gaps = 59/392 (15%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVR------GDTGPQGDKGIAGCPGA 1447
            PGIPG  G RG     G+ GL G  G +G+ G+PG+       G  G  G  G++G PG 
Sbjct: 645  PGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGP 704

Query: 1448 WGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPG---IKGEKGDPGSQGSPGSRGAPGQ 1504
             G+KG KG+ GP G  G+ G  G +G  G  G+PG   + G  GDPG +GS G  G PG 
Sbjct: 705  PGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGL 764

Query: 1505 YGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRG 1564
            +G  G  G+ G PG    + G++G  G  G  G  G++G  G   + G  G  G  G+ G
Sbjct: 765  FGLPGSDGERGLPG----VPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPG 820

Query: 1565 VSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPG 1624
            + G+ G  GP G  G +G++G  GS G PG KG+KG QG  G  G PG  G KGS G PG
Sbjct: 821  LIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPG 880

Query: 1625 LLGKKGEP---------------------GLPGDLGPVGQT---GQRGRQGDSGIPG-YG 1659
              G +G+P                     G PGD+GP G     G +G+ G  G+PG  G
Sbjct: 881  FPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRG 940

Query: 1660 QMGRKGVKGP---------------RGFPGDAGQKGDIGNPGIPGGPGP------KGFRG 1698
            Q+G +G +GP               +GFPG  G  G  G PG PG PGP       GF G
Sbjct: 941  QLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIG 1000

Query: 1699 LALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
            L    G+ GE+G RG+ GPPG  G KG  G P
Sbjct: 1001 LVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHP 1032



 Score =  249 bits (636), Expect = 2e-65
 Identities = 150/372 (40%), Positives = 185/372 (49%), Gaps = 37/372 (9%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG+ G  G  G   +KG +G  G  G  GE G  G+ G+ GP G  G+ G  G  G+ G 
Sbjct: 1188 PGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGK 1247

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD 1513
            +G  G  G  G  G  G  GE G  G PG  G  G  GS+GS G  GAPG+ G +G PG 
Sbjct: 1248 QGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGL 1307

Query: 1514 PGNPGQNNNI-----KGQKGSKGEQGRQGRS-------------GQKGVQGSPSSRGSRG 1555
             G  G    +      G KG KGEQG  G++             G +G +G P   G  G
Sbjct: 1308 AGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPG 1367

Query: 1556 REGQRGLRGVSGEPGNPG---------PTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKG 1606
            +EG +GLRG  G+ G PG         P G+ GAEG +G QG  G PGR+G +G QG  G
Sbjct: 1368 QEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPG 1427

Query: 1607 P------QGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGY-- 1658
            P      QG  G+ G  G  GR G  G++GE G  GD GP+G  G+RG  G +G+PG   
Sbjct: 1428 PRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQG 1487

Query: 1659 --GQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPG 1716
              G  G  G+ G  G PG  G +G  G PG  G PG KG  G +  +G  G  G  G  G
Sbjct: 1488 PPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKG 1547

Query: 1717 PPGQRGIKGMAG 1728
            PPG  G KG+ G
Sbjct: 1548 PPGDIGFKGIQG 1559



 Score =  248 bits (632), Expect = 7e-65
 Identities = 150/362 (41%), Positives = 186/362 (51%), Gaps = 27/362 (7%)

Query: 1394 PGIPGP------HGTRGLQAMKGSQGLKGSRGHRGEDGNPGVR------GDTGPQGDKGI 1441
            PG+PG        G RG     G+ GL G  G +G+ G+PG+       G  G  G  G+
Sbjct: 639  PGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGL 698

Query: 1442 AGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFP---GIKGEKGDPGSQGS--- 1495
            +G PG  G+KG KG+ GP G  G+ G  G +G  G  G+P   G+ G  GDPG +GS   
Sbjct: 699  SGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGY 758

Query: 1496 ---PGSRGAPGQYGEKGFPGDPGNPGQNN--NIKGQKGSKGEQGRQGRSGQKGVQGSPSS 1550
               PG  G PG  GE+G PG PG  G+       G  G +G  G  G  G+ G+ G P  
Sbjct: 759  IGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGV 818

Query: 1551 RGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGS 1610
             G  G  G  G  G  G  G  G  G++G  GL+G +G QG PG  G+ G QG KG QG 
Sbjct: 819  PGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGL 878

Query: 1611 PGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGVKGP 1669
            PG  GA+G  G  G +G KG  G PG  GP G  G  G  GD+G  G  G+ G +G+ GP
Sbjct: 879  PGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGP 938

Query: 1670 RGFPGDAGQKGDIGNPGIP---GGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGM 1726
            RG  G  G +G +G PG P   G PG KGF G     G+KGE G  G PGP G++G  G 
Sbjct: 939  RGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGF 998

Query: 1727 AG 1728
             G
Sbjct: 999  IG 1000



 Score =  246 bits (629), Expect = 2e-64
 Identities = 151/364 (41%), Positives = 183/364 (50%), Gaps = 35/364 (9%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G+PG  G RG   M G  G+ G RG  G DGNPG  G  GP G  G+ G  G  G  G  
Sbjct: 775  GLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYP 834

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDP 1514
            G  G KG  G  G  GL G++G  G PG+ G   DPG QG  GS+G PG  G +G PG  
Sbjct: 835  GPKGMKGLMGSVGEPGLKGDKGEQGVPGVSG---DPGFQGDKGSQGLPGFPGARGKPGPL 891

Query: 1515 GNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGL---RGVSGEPGN 1571
            G  G     KG  G  G  G +G  G  G  G     G +G+ G RGL   RG  G  G+
Sbjct: 892  GKVGD----KGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGD 947

Query: 1572 PGPTGTLGAEGLQGPQGSQGNPGR------KGEKGSQGQKGPQGSPGLMGAKGSTGRPGL 1625
             GP G  GA GL+G  G +G PGR      KGE G  G+ GP G  G MG  G  G PG+
Sbjct: 948  EGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGI 1007

Query: 1626 LGKKGE------------------PGLPGDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGV 1666
            +G+KG+                  PG+PG +G  G+ G +G  G  G PG  G  GR+G 
Sbjct: 1008 VGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGP 1067

Query: 1667 KGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGM 1726
            +GP G  G+ G +G  G PG  G PG  G +G+A   G  G  G  G+PGP G  G KG+
Sbjct: 1068 RGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGL 1127

Query: 1727 AGQP 1730
             G+P
Sbjct: 1128 PGEP 1131



 Score =  246 bits (627), Expect = 3e-64
 Identities = 157/393 (39%), Positives = 193/393 (49%), Gaps = 60/393 (15%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPG---VRGDTGPQGDKGIAGCPGAWGQ 1450
            PG PGP G +G     G  G KG  G  GE G PG   ++GD GP G  G  G  G  G+
Sbjct: 1128 PGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGE 1187

Query: 1451 KGLKGFSGPKGG---------------HGDDGIDGLDGEEGCHGFPGI---------KGE 1486
             GL+G SGP G                HG+ G +GL GE+G  G PG+          G+
Sbjct: 1188 PGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGK 1247

Query: 1487 KGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQG 1546
            +G+ G  G+ G++G  GQ GE G PGDPG PG      G KGS+G  G  G  G+ G QG
Sbjct: 1248 QGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGT----PGPKGSRGSLGPTGAPGRMGAQG 1303

Query: 1547 SPSSRGSRGREG---------QRGLRGVSGEPGN----PGPTGTLGAEGLQGPQGSQGNP 1593
             P   G  G +G          +G +G  GE G     PGP G  G  G +G +G  G+P
Sbjct: 1304 EPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDP 1363

Query: 1594 GRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDS 1653
            G  G++G QG +G  G  G  G  G  G PG  G KG  G  G  G  G  G+RG QG  
Sbjct: 1364 GYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQ 1423

Query: 1654 GIPG----YGQMGRKGVKGPRGFP---GDAGQKGDIGNPGIPGGPGPKGFRGLALTVGL- 1705
            G+PG     G+ G +G+ GP G P   G AGQ+G+ G+ G PG  GP G RG     GL 
Sbjct: 1424 GLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLP 1483

Query: 1706 --------KGEEGSRGLPGPPGQRGIKGMAGQP 1730
                    KGE G  G  GPPG+RG +G  G P
Sbjct: 1484 GAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLP 1516



 Score =  228 bits (580), Expect = 8e-59
 Identities = 135/325 (41%), Positives = 168/325 (51%), Gaps = 26/325 (8%)

Query: 1427 PGVRGDTGPQGDKGIAGCPGAWGQKGLKGFSGPK---GGHGDDGIDGLDGEEGCHGFPGI 1483
            P + G  GP+GD G+ G PG  G  G+ G  GP+   G +G+ G+ G  G +G  G PG+
Sbjct: 621  PLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGL 680

Query: 1484 K------GEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQG 1537
                   G KGD G  G  G+ G PG+ G KG+PG  G+PG+     G +GS G +G  G
Sbjct: 681  SPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQ-PGPEGSPGAKGYPG 739

Query: 1538 RSGQKGVQGSPSSRGSRGREGQRGLRGVSGE------PGNPGPTGTLGAEGLQGPQGSQG 1591
            R G  G  G P  +GSRG  G  GL G+ G       PG PG  G +G  G  G  G +G
Sbjct: 740  RQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERG 799

Query: 1592 NPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQG 1651
             PG  G  G  G  GP G PGL+G  G  G  G  G KG  GL G +G  G  G +G QG
Sbjct: 800  PPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQG 859

Query: 1652 DSGI---PGY----GQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVG 1704
              G+   PG+    G  G  G  G RG PG  G+ GD G+ G PG PGP+GF G    +G
Sbjct: 860  VPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPG---DIG 916

Query: 1705 LKGEEGSRGLPGPPGQRGIKGMAGQ 1729
              G+ G  G+ G PG RG+ G  GQ
Sbjct: 917  PPGDNGPEGMKGKPGARGLPGPRGQ 941



 Score =  220 bits (560), Expect = 2e-56
 Identities = 130/321 (40%), Positives = 164/321 (51%), Gaps = 27/321 (8%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGN-------PGVRGDTGPQGDKGIAGCPG 1446
            PG+ G  G +G+    G  G KG +G +GEDG        PG RG  G +GD+G  G PG
Sbjct: 1305 PGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPG 1364

Query: 1447 AWGQKGLKGFSG------------PKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQG 1494
              GQ+G++G  G            P+G  G  G  G +G +G  G  G  G +G  G QG
Sbjct: 1365 YPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQG 1424

Query: 1495 SPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSR 1554
             PG RG  G+ G +G  G  G PG++    GQ+G +G+ G  G  G  G +G+P   G  
Sbjct: 1425 LPGPRGVVGRQGLEGIAGPDGLPGRDGQA-GQQGEQGDDGDPGPMGPAGKRGNPGVAGLP 1483

Query: 1555 GREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLM 1614
            G +G  G +G SG PG  GP G  G EG  G  G+QG PG KG+ G  G+ G  G  GL 
Sbjct: 1484 GAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLF 1543

Query: 1615 GAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG----YGQMGRKGVKGPR 1670
            G KG  G  G  G +G  G PG +G  G  G  G  G SG+PG     G  G  G++GPR
Sbjct: 1544 GPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPR 1603

Query: 1671 GFPGDAGQKGDIGNPGIPGGP 1691
            G PG  G+ G    PG PGGP
Sbjct: 1604 GPPGPRGRPGP---PGPPGGP 1621



 Score =  184 bits (466), Expect = 1e-45
 Identities = 114/278 (41%), Positives = 142/278 (51%), Gaps = 24/278 (8%)

Query: 1476 GCHGFPGIKGEKGDPGSQGSPGSR------GAPGQYGEKGFPGDPGNPGQNN--NIKGQK 1527
            G   FP + G  G  G  G PG        G PG  G +G PG  GNPG       KGQK
Sbjct: 616  GSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQK 675

Query: 1528 G------SKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAE 1581
            G       K   G +G  G  G+ G+P   G +G +G  G  G  GE G PGP G+ GA+
Sbjct: 676  GDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAK 735

Query: 1582 GLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGE---PGLPGDL 1638
            G  G QG  G  G  G KGS+G  G  G  GL G+ G  G PG+ GK+G+   PG PG  
Sbjct: 736  GYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVF 795

Query: 1639 GPVGQTGQRGRQGDSGIPG----YGQMGRKGVKGPRGFPGDAGQK---GDIGNPGIPGGP 1691
            G  G  G  G  G+ G+PG     G +G  GV GP G+PG  G K   G +G PG+ G  
Sbjct: 796  GERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDK 855

Query: 1692 GPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQ 1729
            G +G  G++   G +G++GS+GLPG PG RG  G  G+
Sbjct: 856  GEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGK 893



 Score =  168 bits (425), Expect = 7e-41
 Identities = 112/280 (40%), Positives = 137/280 (48%), Gaps = 53/280 (18%)

Query: 1479 GFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGR 1538
            G PG KG+ G PG  G PG  G PG  G +G PG  GNPG    + G  G+KG++G  G 
Sbjct: 625  GPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPG----LPGPPGAKGQKGDPGL 680

Query: 1539 SGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGE 1598
            S  K   G+         +G  GL G+SG PG PG             +G +G PG  G 
Sbjct: 681  SPGKAHDGA---------KGDMGLPGLSGNPGPPGR------------KGHKGYPGPAGH 719

Query: 1599 KGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG- 1657
             G QGQ GP+GSPG  G  G  G PG +G  G  G  G +G  G  G  G  G+ G+PG 
Sbjct: 720  PGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGV 779

Query: 1658 ------YGQMGRKGVKGPRGFPGDAGQKGDIGNPGIP---------------GGPGPKGF 1696
                   G  G  GV G RG PG  G  G++G PG P               G PGPKG 
Sbjct: 780  PGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGM 839

Query: 1697 RGLALTV---GLKGEEGSRGLP---GPPGQRGIKGMAGQP 1730
            +GL  +V   GLKG++G +G+P   G PG +G KG  G P
Sbjct: 840  KGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLP 879



 Score =  134 bits (338), Expect = 9e-31
 Identities = 84/179 (46%), Positives = 94/179 (52%), Gaps = 10/179 (5%)

Query: 1562 LRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGL---MGAKG 1618
            L G +  P   GP G  G  GL GP G  G PG  G +G +G  GP G+PGL    GAKG
Sbjct: 614  LAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKG 673

Query: 1619 STGRPGLLGKKGEPGLPGDLGPVGQTGQ---RGRQGDSGIPG-YGQMGRKGVKGPRGFPG 1674
              G PGL   K   G  GD+G  G +G     GR+G  G PG  G  G +G  GP G PG
Sbjct: 674  QKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPG 733

Query: 1675 DAGQKGDIGNPGIPGGPGPKGFR---GLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
              G  G  G PG  G PGPKG R   GL    GL G +G RGLPG PG+RG  GM G P
Sbjct: 734  AKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFP 792



 Score = 67.4 bits (163), Expect = 2e-10
 Identities = 55/142 (38%), Positives = 65/142 (45%), Gaps = 20/142 (14%)

Query: 1602 QGQKGPQGSPGLMGAKG----STGRPGLLGKK-----GEPGLPGDLGPVGQTGQRGRQGD 1652
            Q Q   Q +P L+ A      S+ RP   G       G    P  +GP G  G  G  G 
Sbjct: 579  QPQPSQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGP 638

Query: 1653 SGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLA---LTVGLKGEE 1709
             G+PG    G  G +GPRG PG  G  G    PG PG  G KG  GL+      G KG+ 
Sbjct: 639  PGLPGLP--GIPGARGPRGPPGPYGNPG---LPGPPGAKGQKGDPGLSPGKAHDGAKGDM 693

Query: 1710 GSRGL---PGPPGQRGIKGMAG 1728
            G  GL   PGPPG++G KG  G
Sbjct: 694  GLPGLSGNPGPPGRKGHKGYPG 715


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  273 bits (699), Expect = 1e-72
 Identities = 158/369 (42%), Positives = 187/369 (50%), Gaps = 37/369 (10%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PG  G +G     G  G  G +G RG  G PG RG  GP G +G  G  G  G+ G 
Sbjct: 855  PGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGP 914

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD 1513
            KG SG  G  G  G  G  G +G  GFPG KG  G PG  G PG    PGQ GE GF G 
Sbjct: 915  KGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGH---PGQRGETGFQGK 971

Query: 1514 PGNPGQNNNI-----------------KGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGR 1556
             G PG    +                  G  G  GEQG  G +G++G +G P  +G  G+
Sbjct: 972  TGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 1031

Query: 1557 EGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGS---------QGQKGP 1607
            +G  GLRG  GE G PG  G  G +G +GPQG  G  G  GE+GS          G+ GP
Sbjct: 1032 DGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP 1091

Query: 1608 QGSPGLMGAKGSTGRPGLLGK------KGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQM 1661
            QG PG  G KG+ G  G  G       +G  GLPG  GP G  G+ G +G+ G P  GQ 
Sbjct: 1092 QGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEP--GQK 1149

Query: 1662 GRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQR 1721
            G KG KG  G PG  G +G +G PGI GG G  G RG     G KG+EG+RG PGPPG  
Sbjct: 1150 GSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPI 1209

Query: 1722 GIKGMAGQP 1730
            G++G+ G P
Sbjct: 1210 GLQGLPGPP 1218



 Score =  268 bits (686), Expect = 4e-71
 Identities = 156/352 (44%), Positives = 185/352 (52%), Gaps = 23/352 (6%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PGP G RG+Q   G  G  G RG  G DG  G+ G+ G +GD+G  G PG  G KG +
Sbjct: 568  GDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHR 627

Query: 1455 GFSGPKGGHG---DDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFP 1511
            G  GP+G  G   DDG+ G DGE G  G PG  G +G  G +G+PG+ G PG  G  G P
Sbjct: 628  GERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPP 687

Query: 1512 GDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGN 1571
            G  GN G      G  G +G  G QG  G +G  G P  +G +G+ G  GL G  G PG+
Sbjct: 688  GPKGNMGPQGE-PGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 746

Query: 1572 PGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGE 1631
            PG  G  G +G  GP G QG  G  G +   G KG  G  GL G+KG  G  G  G KG+
Sbjct: 747  PGKEGQSGEKGALGPPGPQGPIGYPGPR---GVKGADGVRGLKGSKGEKGEDGFPGFKGD 803

Query: 1632 PGLPGDLGPVGQTGQR---------GRQGDSGIPG----YGQMGRKGVKGPRGFPGDAGQ 1678
             GL GD G VGQ G R         GR G +G PG     G+ G+ GV G  G+PG  G 
Sbjct: 804  MGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGP 863

Query: 1679 KGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
            KG  G PG PG  G KG RG+A   G  G  G RG  GP G RG +G  G+P
Sbjct: 864  KGSTGFPGFPGANGEKGARGVA---GKPGPRGQRGPTGPRGSRGARGPTGKP 912



 Score =  267 bits (683), Expect = 9e-71
 Identities = 157/363 (43%), Positives = 191/363 (52%), Gaps = 31/363 (8%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PGP G  GLQ + G  G KG  G  G  G PG  G  GPQG  G  G  G  G  G  
Sbjct: 1201 GFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSV 1260

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGD---PGSQGSPGSRGAPGQYGEKG-- 1509
            G  G KG  G+ G  G  GE G  G  G +GEKG+   PG+ G PG++G PG  G KG  
Sbjct: 1261 GGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP 1320

Query: 1510 ----FPGDPGNPGQNNNI--------KGQKGSKGEQGRQGRSGQKGVQGSPSSRG----- 1552
                FPGDPG PG+            KG+ G  G+ G  G SG+ G  G P  RG     
Sbjct: 1321 GPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAA 1380

Query: 1553 -SRGREGQRGLRGVSGEPGNPGPTGTLGAEG---LQGPQGSQGNPGRKGEKGSQGQKGPQ 1608
             + GR+G++G +G +G  G PG TG +G +G     GP+G +G PG  GE+G  G  G  
Sbjct: 1381 GAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQD 1440

Query: 1609 GSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKG 1668
            G PG MG  G  G  G  G KGE G PG +G +G  G++G +GD G+P  G  G  G KG
Sbjct: 1441 GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP--GTQGSPGAKG 1498

Query: 1669 PRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAG 1728
              G PG AG  G  G PG+PG  GPKG +G   + G  G++G  GLPGPPG  G  G   
Sbjct: 1499 DGGIPGPAGPLGPPGPPGLPGPQGPKGNKG---STGPAGQKGDSGLPGPPGSPGPPGEVI 1555

Query: 1729 QPV 1731
            QP+
Sbjct: 1556 QPL 1558



 Score =  259 bits (661), Expect = 3e-68
 Identities = 155/398 (38%), Positives = 186/398 (46%), Gaps = 65/398 (16%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G+PGP G  G    KG QG  G  G  G DG PG  G  G  G+KG  G PG  G  G  
Sbjct: 712  GLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYP 771

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGE------------------------KGDP 1490
            G  G KG  G  G+ G  GE+G  GFPG KG+                        KG  
Sbjct: 772  GPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRA 831

Query: 1491 GSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSS 1550
            G  G PG  G  G+ G+ G PG PG PG+    KG  G  G  G  G  G +GV G P  
Sbjct: 832  GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGP-KGSTGFPGFPGANGEKGARGVAGKPGP 890

Query: 1551 RGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQ-------------------- 1590
            RG RG  G RG RG  G  G PGP GT G +G  GP G +                    
Sbjct: 891  RGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGP 950

Query: 1591 -------GNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQ 1643
                   G+PG++GE G QG+ GP G  G++G +G TG  G +G++G PG PG  G  G 
Sbjct: 951  PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGL 1010

Query: 1644 TGQRGRQGDSGIPG-YGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGG------------ 1690
             G  G++G  G PG  G  G+ G  G RGFPG+ G  G  G PG+ GG            
Sbjct: 1011 PGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGS 1070

Query: 1691 PGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAG 1728
            PG +G  G A  +GL G  G +G PGP G++G  G  G
Sbjct: 1071 PGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG 1108



 Score =  254 bits (650), Expect = 6e-67
 Identities = 148/357 (41%), Positives = 181/357 (50%), Gaps = 27/357 (7%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PGP G  G     G +G  G RG  G  G PG++G  GPQG  G  G PG   ++G  
Sbjct: 1021 GDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG---ERGSA 1077

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDP 1514
            G +GP G  G  G  G  G  G  G PG KG +G  G  G  G  G PG  G  G PG+ 
Sbjct: 1078 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGED 1137

Query: 1515 GNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQ---GSPSSRGSRGREGQRGLRGVSGEPGN 1571
            G+ G+     GQKGSKG++G  G  G  G+Q   G+P   G  G  G RG +G+ G+ G+
Sbjct: 1138 GDKGEIGE-PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGD 1196

Query: 1572 ------PGPTGTLGAEGLQGPQGSQGN------------PGRKGEKGSQGQKGPQGSPGL 1613
                  PGP G +G +GL GP G +G             PG +G +G  G  GPQG PG 
Sbjct: 1197 EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGS 1256

Query: 1614 MGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFP 1673
            +G+ G  G  G  G+ G PG PG+ G  G  G+RG +G++G P  G  G  G KGP G  
Sbjct: 1257 VGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPP--GAAGPPGAKGPPGDD 1314

Query: 1674 GDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
            G  G  G +G PG PG PG  G  G     G KGE+G  G PGPPG  G  G  G P
Sbjct: 1315 GPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPP 1371



 Score =  250 bits (639), Expect = 1e-65
 Identities = 150/360 (41%), Positives = 182/360 (50%), Gaps = 24/360 (6%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAG---CPGAWGQ 1450
            PG PG  G RG   + G  G KG RG RG  G PG  GD G +G+ G  G    PG  G 
Sbjct: 603  PGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGP 662

Query: 1451 KGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGF 1510
            +GL G  G  G  G  G+ G+DG  G  G  G +GE G PG QG+PG +G PG  G  G 
Sbjct: 663  RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGP 722

Query: 1511 PGDPGNPGQNN--NIKGQKGSKGEQGRQGRSGQKGVQGS---------PSSRGSRGREGQ 1559
            PG+ G  G+     + G  G  G  G++G+SG+KG  G          P  RG +G +G 
Sbjct: 723  PGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGV 782

Query: 1560 RGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGS 1619
            RGL+G  GE G  G  G  G  GL+G +G  G  G +GE G +G KG  G  G  G  G 
Sbjct: 783  RGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQ 842

Query: 1620 TGRPGLLGKKGEPGLPGDLGPVGQT---------GQRGRQGDSGIPG-YGQMGRKGVKGP 1669
             G  G LG  G PG PG  GP G T         G++G +G +G PG  GQ G  G +G 
Sbjct: 843  AGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGS 902

Query: 1670 RGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQ 1729
            RG  G  G+ G  G  G  G PGP G RG     G  G  G +G PGPPG+ G+ G  GQ
Sbjct: 903  RGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQ 962



 Score =  250 bits (639), Expect = 1e-65
 Identities = 155/360 (43%), Positives = 188/360 (52%), Gaps = 30/360 (8%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGP---------QGDKGIAGC 1444
            PG PGP G  G    KG+ G KG +G  G DG  G  G  GP          GDKG  G 
Sbjct: 1086 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1145

Query: 1445 PGAWGQKGLKGFSGP------KGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGS 1498
            PG  G KG KG +GP      +G  G  GI G DGE G  G  G+ G+KGD G++G P  
Sbjct: 1146 PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFP-- 1203

Query: 1499 RGAPGQYGEKGFPGDPGNPGQNNNI--KGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGR 1556
             G PG  G +G PG PG  G+N ++   G  G  G +G QG +G  G QG P S GS G 
Sbjct: 1204 -GPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGG 1262

Query: 1557 EGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGR---KGEKGSQGQKGPQGSPGL 1613
             G++G  G +G PG PG  G  G +G +G +G  G PG     G KG  G  GP+G+PG 
Sbjct: 1263 VGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGP 1322

Query: 1614 MGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG----YGQMGRKGVKGP 1669
            +G  G  G PG  G  G+ G+ GD G  G  GQ G  G SG  G     G+ G  G  G 
Sbjct: 1323 VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGA 1382

Query: 1670 RGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQ 1729
             G  G+ G KG+ G  G PG  GP G +G A   G  G EG RG+PGP G++G+ G AGQ
Sbjct: 1383 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPA---GKPGPEGLRGIPGPVGEQGLPGAAGQ 1439



 Score =  249 bits (636), Expect = 2e-65
 Identities = 148/346 (42%), Positives = 183/346 (52%), Gaps = 18/346 (5%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG  G  G  G + M G  G KG RG  G  G PG +G  G +G +G  G PG  G +G 
Sbjct: 588  PGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGE 647

Query: 1454 KGFSGPKGGHGDDGIDGL---DGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGF 1510
             G  GP+G  G+ G  GL    G  G  G PG+ G  G PG +G+ G +G PG  G++G 
Sbjct: 648  DGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGN 707

Query: 1511 PGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPG 1570
            PG  G PG    I G  G KG QG+ G +G  G  G P   G  G+EGQ G +G  G PG
Sbjct: 708  PGPQGLPGPQGPI-GPPGEKGPQGKPGLAGLPGADGPP---GHPGKEGQSGEKGALGPPG 763

Query: 1571 NPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGK-- 1628
              GP G  G  G++G  G +G  G KGEKG  G  G +G  GL G +G  G+ G  G+  
Sbjct: 764  PQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDG 823

Query: 1629 ----KGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGN 1684
                KG  G  GD GP GQ G++G+ G  G+PGY   GR+G KG  GFPG  G  G+ G 
Sbjct: 824  PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGY--PGRQGPKGSTGFPGFPGANGEKGA 881

Query: 1685 PGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
             G+ G PGP+G RG     G +G  G+RG  G PG +G  G  G P
Sbjct: 882  RGVAGKPGPRGQRG---PTGPRGSRGARGPTGKPGPKGTSGGDGPP 924



 Score =  239 bits (609), Expect = 3e-62
 Identities = 151/407 (37%), Positives = 193/407 (47%), Gaps = 77/407 (18%)

Query: 1395 GIPGPHGTRGLQAMK----GSQG--------------------LKGSRGHRGEDGNPGVR 1430
            G+PGP GT  +   +    GS+G                    L+G  G  G  G PG  
Sbjct: 496  GLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPV 555

Query: 1431 GDTGPQGDKGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDP 1490
            G  G  G KG +G PG  G +G++G  GP G  G  G  G DG  G  G PG KG++G  
Sbjct: 556  GGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD 615

Query: 1491 GSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSS 1550
            G  G PG +G  G+ G +G PG PG+ G    ++G+ G  G +G  G +G +G+ G   +
Sbjct: 616  GLPGLPGDKGHRGERGPQGPPGPPGDDG----MRGEDGEIGPRGLPGEAGPRGLLGPRGT 671

Query: 1551 RGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGS 1610
             G+ G+ G  G+ G  G  GN GP G  G  G QG  G QG PG +G  G  G+KGPQG 
Sbjct: 672  PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 731

Query: 1611 PGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQ---------------------TGQRGR 1649
            PGL G  G+ G PG  GK+G+ G  G LGP G                       G +G 
Sbjct: 732  PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 791

Query: 1650 QGDSGIPGY----------------------GQMGRKGVKGPRGFP---GDAGQKGDIGN 1684
            +G+ G PG+                      G  G KG  GP G P   G AG+KG +G 
Sbjct: 792  KGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGV 851

Query: 1685 PGIPGGP---GPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAG 1728
            PG+PG P   GPKG  G     G  GE+G+RG+ G PG RG +G  G
Sbjct: 852  PGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTG 898



 Score =  188 bits (477), Expect = 7e-47
 Identities = 123/310 (39%), Positives = 155/310 (50%), Gaps = 8/310 (2%)

Query: 1423 EDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFSGP-KGGHGDDGIDGLDGEEGCHGFP 1481
            E+  PGV  +T    +  I G  GA+G+KG KG     + G   +G  G  G  G  G P
Sbjct: 411  EEFGPGVPAETDIT-ETSING-HGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPP 468

Query: 1482 GIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQ 1541
            G++G  G PG    PG RG PG+ G  G  G PG PG    +  + G  G +G    S Q
Sbjct: 469  GLQGPTGPPGD---PGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKG-PTISAQ 524

Query: 1542 KGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGS 1601
            +    +   +      G  G  G++G PG  G  G+ GA+G  G  G QG  G +G  G 
Sbjct: 525  EAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGP 584

Query: 1602 QGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG-YGQ 1660
             G+ G +G PG  G +G  G PG  G +G  GLPG  G  G  G+RG QG  G PG  G 
Sbjct: 585  TGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGM 644

Query: 1661 MGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQ 1720
             G  G  GPRG PG+AG +G +G  G PG PG  G  G+    G KG  G +G PGPPGQ
Sbjct: 645  RGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQ 704

Query: 1721 RGIKGMAGQP 1730
            +G  G  G P
Sbjct: 705  QGNPGPQGLP 714


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  273 bits (699), Expect = 1e-72
 Identities = 158/369 (42%), Positives = 187/369 (50%), Gaps = 37/369 (10%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PG  G +G     G  G  G +G RG  G PG RG  GP G +G  G  G  G+ G 
Sbjct: 804  PGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGP 863

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD 1513
            KG SG  G  G  G  G  G +G  GFPG KG  G PG  G PG    PGQ GE GF G 
Sbjct: 864  KGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGH---PGQRGETGFQGK 920

Query: 1514 PGNPGQNNNI-----------------KGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGR 1556
             G PG    +                  G  G  GEQG  G +G++G +G P  +G  G+
Sbjct: 921  TGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 980

Query: 1557 EGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGS---------QGQKGP 1607
            +G  GLRG  GE G PG  G  G +G +GPQG  G  G  GE+GS          G+ GP
Sbjct: 981  DGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP 1040

Query: 1608 QGSPGLMGAKGSTGRPGLLGK------KGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQM 1661
            QG PG  G KG+ G  G  G       +G  GLPG  GP G  G+ G +G+ G P  GQ 
Sbjct: 1041 QGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEP--GQK 1098

Query: 1662 GRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQR 1721
            G KG KG  G PG  G +G +G PGI GG G  G RG     G KG+EG+RG PGPPG  
Sbjct: 1099 GSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPI 1158

Query: 1722 GIKGMAGQP 1730
            G++G+ G P
Sbjct: 1159 GLQGLPGPP 1167



 Score =  268 bits (686), Expect = 4e-71
 Identities = 156/352 (44%), Positives = 185/352 (52%), Gaps = 23/352 (6%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PGP G RG+Q   G  G  G RG  G DG  G+ G+ G +GD+G  G PG  G KG +
Sbjct: 517  GDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHR 576

Query: 1455 GFSGPKGGHG---DDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFP 1511
            G  GP+G  G   DDG+ G DGE G  G PG  G +G  G +G+PG+ G PG  G  G P
Sbjct: 577  GERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPP 636

Query: 1512 GDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGN 1571
            G  GN G      G  G +G  G QG  G +G  G P  +G +G+ G  GL G  G PG+
Sbjct: 637  GPKGNMGPQGE-PGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 695

Query: 1572 PGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGE 1631
            PG  G  G +G  GP G QG  G  G +   G KG  G  GL G+KG  G  G  G KG+
Sbjct: 696  PGKEGQSGEKGALGPPGPQGPIGYPGPR---GVKGADGVRGLKGSKGEKGEDGFPGFKGD 752

Query: 1632 PGLPGDLGPVGQTGQR---------GRQGDSGIPG----YGQMGRKGVKGPRGFPGDAGQ 1678
             GL GD G VGQ G R         GR G +G PG     G+ G+ GV G  G+PG  G 
Sbjct: 753  MGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGP 812

Query: 1679 KGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
            KG  G PG PG  G KG RG+A   G  G  G RG  GP G RG +G  G+P
Sbjct: 813  KGSTGFPGFPGANGEKGARGVA---GKPGPRGQRGPTGPRGSRGARGPTGKP 861



 Score =  267 bits (683), Expect = 9e-71
 Identities = 157/363 (43%), Positives = 191/363 (52%), Gaps = 31/363 (8%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PGP G  GLQ + G  G KG  G  G  G PG  G  GPQG  G  G  G  G  G  
Sbjct: 1150 GFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSV 1209

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGD---PGSQGSPGSRGAPGQYGEKG-- 1509
            G  G KG  G+ G  G  GE G  G  G +GEKG+   PG+ G PG++G PG  G KG  
Sbjct: 1210 GGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP 1269

Query: 1510 ----FPGDPGNPGQNNNI--------KGQKGSKGEQGRQGRSGQKGVQGSPSSRG----- 1552
                FPGDPG PG+            KG+ G  G+ G  G SG+ G  G P  RG     
Sbjct: 1270 GPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAA 1329

Query: 1553 -SRGREGQRGLRGVSGEPGNPGPTGTLGAEG---LQGPQGSQGNPGRKGEKGSQGQKGPQ 1608
             + GR+G++G +G +G  G PG TG +G +G     GP+G +G PG  GE+G  G  G  
Sbjct: 1330 GAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQD 1389

Query: 1609 GSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKG 1668
            G PG MG  G  G  G  G KGE G PG +G +G  G++G +GD G+P  G  G  G KG
Sbjct: 1390 GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP--GTQGSPGAKG 1447

Query: 1669 PRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAG 1728
              G PG AG  G  G PG+PG  GPKG +G   + G  G++G  GLPGPPG  G  G   
Sbjct: 1448 DGGIPGPAGPLGPPGPPGLPGPQGPKGNKG---STGPAGQKGDSGLPGPPGSPGPPGEVI 1504

Query: 1729 QPV 1731
            QP+
Sbjct: 1505 QPL 1507



 Score =  259 bits (661), Expect = 3e-68
 Identities = 155/398 (38%), Positives = 186/398 (46%), Gaps = 65/398 (16%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G+PGP G  G    KG QG  G  G  G DG PG  G  G  G+KG  G PG  G  G  
Sbjct: 661  GLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYP 720

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGE------------------------KGDP 1490
            G  G KG  G  G+ G  GE+G  GFPG KG+                        KG  
Sbjct: 721  GPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRA 780

Query: 1491 GSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSS 1550
            G  G PG  G  G+ G+ G PG PG PG+    KG  G  G  G  G  G +GV G P  
Sbjct: 781  GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGP-KGSTGFPGFPGANGEKGARGVAGKPGP 839

Query: 1551 RGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQ-------------------- 1590
            RG RG  G RG RG  G  G PGP GT G +G  GP G +                    
Sbjct: 840  RGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGP 899

Query: 1591 -------GNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQ 1643
                   G+PG++GE G QG+ GP G  G++G +G TG  G +G++G PG PG  G  G 
Sbjct: 900  PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGL 959

Query: 1644 TGQRGRQGDSGIPG-YGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGG------------ 1690
             G  G++G  G PG  G  G+ G  G RGFPG+ G  G  G PG+ GG            
Sbjct: 960  PGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGS 1019

Query: 1691 PGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAG 1728
            PG +G  G A  +GL G  G +G PGP G++G  G  G
Sbjct: 1020 PGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG 1057



 Score =  254 bits (650), Expect = 6e-67
 Identities = 148/357 (41%), Positives = 181/357 (50%), Gaps = 27/357 (7%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PGP G  G     G +G  G RG  G  G PG++G  GPQG  G  G PG   ++G  
Sbjct: 970  GDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG---ERGSA 1026

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDP 1514
            G +GP G  G  G  G  G  G  G PG KG +G  G  G  G  G PG  G  G PG+ 
Sbjct: 1027 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGED 1086

Query: 1515 GNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQ---GSPSSRGSRGREGQRGLRGVSGEPGN 1571
            G+ G+     GQKGSKG++G  G  G  G+Q   G+P   G  G  G RG +G+ G+ G+
Sbjct: 1087 GDKGEIGE-PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGD 1145

Query: 1572 ------PGPTGTLGAEGLQGPQGSQGN------------PGRKGEKGSQGQKGPQGSPGL 1613
                  PGP G +G +GL GP G +G             PG +G +G  G  GPQG PG 
Sbjct: 1146 EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGS 1205

Query: 1614 MGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFP 1673
            +G+ G  G  G  G+ G PG PG+ G  G  G+RG +G++G P  G  G  G KGP G  
Sbjct: 1206 VGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPP--GAAGPPGAKGPPGDD 1263

Query: 1674 GDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
            G  G  G +G PG PG PG  G  G     G KGE+G  G PGPPG  G  G  G P
Sbjct: 1264 GPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPP 1320



 Score =  250 bits (639), Expect = 1e-65
 Identities = 150/360 (41%), Positives = 182/360 (50%), Gaps = 24/360 (6%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAG---CPGAWGQ 1450
            PG PG  G RG   + G  G KG RG RG  G PG  GD G +G+ G  G    PG  G 
Sbjct: 552  PGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGP 611

Query: 1451 KGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGF 1510
            +GL G  G  G  G  G+ G+DG  G  G  G +GE G PG QG+PG +G PG  G  G 
Sbjct: 612  RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGP 671

Query: 1511 PGDPGNPGQNN--NIKGQKGSKGEQGRQGRSGQKGVQGS---------PSSRGSRGREGQ 1559
            PG+ G  G+     + G  G  G  G++G+SG+KG  G          P  RG +G +G 
Sbjct: 672  PGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGV 731

Query: 1560 RGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGS 1619
            RGL+G  GE G  G  G  G  GL+G +G  G  G +GE G +G KG  G  G  G  G 
Sbjct: 732  RGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQ 791

Query: 1620 TGRPGLLGKKGEPGLPGDLGPVGQT---------GQRGRQGDSGIPG-YGQMGRKGVKGP 1669
             G  G LG  G PG PG  GP G T         G++G +G +G PG  GQ G  G +G 
Sbjct: 792  AGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGS 851

Query: 1670 RGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQ 1729
            RG  G  G+ G  G  G  G PGP G RG     G  G  G +G PGPPG+ G+ G  GQ
Sbjct: 852  RGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQ 911



 Score =  250 bits (639), Expect = 1e-65
 Identities = 155/360 (43%), Positives = 188/360 (52%), Gaps = 30/360 (8%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGP---------QGDKGIAGC 1444
            PG PGP G  G    KG+ G KG +G  G DG  G  G  GP          GDKG  G 
Sbjct: 1035 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1094

Query: 1445 PGAWGQKGLKGFSGP------KGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGS 1498
            PG  G KG KG +GP      +G  G  GI G DGE G  G  G+ G+KGD G++G P  
Sbjct: 1095 PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFP-- 1152

Query: 1499 RGAPGQYGEKGFPGDPGNPGQNNNI--KGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGR 1556
             G PG  G +G PG PG  G+N ++   G  G  G +G QG +G  G QG P S GS G 
Sbjct: 1153 -GPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGG 1211

Query: 1557 EGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGR---KGEKGSQGQKGPQGSPGL 1613
             G++G  G +G PG PG  G  G +G +G +G  G PG     G KG  G  GP+G+PG 
Sbjct: 1212 VGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGP 1271

Query: 1614 MGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG----YGQMGRKGVKGP 1669
            +G  G  G PG  G  G+ G+ GD G  G  GQ G  G SG  G     G+ G  G  G 
Sbjct: 1272 VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGA 1331

Query: 1670 RGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQ 1729
             G  G+ G KG+ G  G PG  GP G +G A   G  G EG RG+PGP G++G+ G AGQ
Sbjct: 1332 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPA---GKPGPEGLRGIPGPVGEQGLPGAAGQ 1388



 Score =  249 bits (636), Expect = 2e-65
 Identities = 148/346 (42%), Positives = 183/346 (52%), Gaps = 18/346 (5%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG  G  G  G + M G  G KG RG  G  G PG +G  G +G +G  G PG  G +G 
Sbjct: 537  PGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGE 596

Query: 1454 KGFSGPKGGHGDDGIDGL---DGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGF 1510
             G  GP+G  G+ G  GL    G  G  G PG+ G  G PG +G+ G +G PG  G++G 
Sbjct: 597  DGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGN 656

Query: 1511 PGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPG 1570
            PG  G PG    I G  G KG QG+ G +G  G  G P   G  G+EGQ G +G  G PG
Sbjct: 657  PGPQGLPGPQGPI-GPPGEKGPQGKPGLAGLPGADGPP---GHPGKEGQSGEKGALGPPG 712

Query: 1571 NPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGK-- 1628
              GP G  G  G++G  G +G  G KGEKG  G  G +G  GL G +G  G+ G  G+  
Sbjct: 713  PQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDG 772

Query: 1629 ----KGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGN 1684
                KG  G  GD GP GQ G++G+ G  G+PGY   GR+G KG  GFPG  G  G+ G 
Sbjct: 773  PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGY--PGRQGPKGSTGFPGFPGANGEKGA 830

Query: 1685 PGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
             G+ G PGP+G RG     G +G  G+RG  G PG +G  G  G P
Sbjct: 831  RGVAGKPGPRGQRG---PTGPRGSRGARGPTGKPGPKGTSGGDGPP 873



 Score =  239 bits (609), Expect = 3e-62
 Identities = 151/407 (37%), Positives = 193/407 (47%), Gaps = 77/407 (18%)

Query: 1395 GIPGPHGTRGLQAMK----GSQG--------------------LKGSRGHRGEDGNPGVR 1430
            G+PGP GT  +   +    GS+G                    L+G  G  G  G PG  
Sbjct: 445  GLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPV 504

Query: 1431 GDTGPQGDKGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDP 1490
            G  G  G KG +G PG  G +G++G  GP G  G  G  G DG  G  G PG KG++G  
Sbjct: 505  GGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD 564

Query: 1491 GSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSS 1550
            G  G PG +G  G+ G +G PG PG+ G    ++G+ G  G +G  G +G +G+ G   +
Sbjct: 565  GLPGLPGDKGHRGERGPQGPPGPPGDDG----MRGEDGEIGPRGLPGEAGPRGLLGPRGT 620

Query: 1551 RGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGS 1610
             G+ G+ G  G+ G  G  GN GP G  G  G QG  G QG PG +G  G  G+KGPQG 
Sbjct: 621  PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 680

Query: 1611 PGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQ---------------------TGQRGR 1649
            PGL G  G+ G PG  GK+G+ G  G LGP G                       G +G 
Sbjct: 681  PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 740

Query: 1650 QGDSGIPGY----------------------GQMGRKGVKGPRGFP---GDAGQKGDIGN 1684
            +G+ G PG+                      G  G KG  GP G P   G AG+KG +G 
Sbjct: 741  KGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGV 800

Query: 1685 PGIPGGP---GPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAG 1728
            PG+PG P   GPKG  G     G  GE+G+RG+ G PG RG +G  G
Sbjct: 801  PGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTG 847



 Score =  188 bits (477), Expect = 7e-47
 Identities = 123/310 (39%), Positives = 155/310 (50%), Gaps = 8/310 (2%)

Query: 1423 EDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFSGP-KGGHGDDGIDGLDGEEGCHGFP 1481
            E+  PGV  +T    +  I G  GA+G+KG KG     + G   +G  G  G  G  G P
Sbjct: 360  EEFGPGVPAETDIT-ETSING-HGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPP 417

Query: 1482 GIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQ 1541
            G++G  G PG    PG RG PG+ G  G  G PG PG    +  + G  G +G    S Q
Sbjct: 418  GLQGPTGPPGD---PGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKG-PTISAQ 473

Query: 1542 KGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGS 1601
            +    +   +      G  G  G++G PG  G  G+ GA+G  G  G QG  G +G  G 
Sbjct: 474  EAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGP 533

Query: 1602 QGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG-YGQ 1660
             G+ G +G PG  G +G  G PG  G +G  GLPG  G  G  G+RG QG  G PG  G 
Sbjct: 534  TGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGM 593

Query: 1661 MGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQ 1720
             G  G  GPRG PG+AG +G +G  G PG PG  G  G+    G KG  G +G PGPPGQ
Sbjct: 594  RGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQ 653

Query: 1721 RGIKGMAGQP 1730
            +G  G  G P
Sbjct: 654  QGNPGPQGLP 663


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  273 bits (699), Expect = 1e-72
 Identities = 158/369 (42%), Positives = 187/369 (50%), Gaps = 37/369 (10%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PG  G +G     G  G  G +G RG  G PG RG  GP G +G  G  G  G+ G 
Sbjct: 843  PGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGP 902

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD 1513
            KG SG  G  G  G  G  G +G  GFPG KG  G PG  G PG    PGQ GE GF G 
Sbjct: 903  KGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGH---PGQRGETGFQGK 959

Query: 1514 PGNPGQNNNI-----------------KGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGR 1556
             G PG    +                  G  G  GEQG  G +G++G +G P  +G  G+
Sbjct: 960  TGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 1019

Query: 1557 EGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGS---------QGQKGP 1607
            +G  GLRG  GE G PG  G  G +G +GPQG  G  G  GE+GS          G+ GP
Sbjct: 1020 DGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP 1079

Query: 1608 QGSPGLMGAKGSTGRPGLLGK------KGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQM 1661
            QG PG  G KG+ G  G  G       +G  GLPG  GP G  G+ G +G+ G P  GQ 
Sbjct: 1080 QGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEP--GQK 1137

Query: 1662 GRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQR 1721
            G KG KG  G PG  G +G +G PGI GG G  G RG     G KG+EG+RG PGPPG  
Sbjct: 1138 GSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPI 1197

Query: 1722 GIKGMAGQP 1730
            G++G+ G P
Sbjct: 1198 GLQGLPGPP 1206



 Score =  268 bits (686), Expect = 4e-71
 Identities = 156/352 (44%), Positives = 185/352 (52%), Gaps = 23/352 (6%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PGP G RG+Q   G  G  G RG  G DG  G+ G+ G +GD+G  G PG  G KG +
Sbjct: 556  GDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHR 615

Query: 1455 GFSGPKGGHG---DDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFP 1511
            G  GP+G  G   DDG+ G DGE G  G PG  G +G  G +G+PG+ G PG  G  G P
Sbjct: 616  GERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPP 675

Query: 1512 GDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGN 1571
            G  GN G      G  G +G  G QG  G +G  G P  +G +G+ G  GL G  G PG+
Sbjct: 676  GPKGNMGPQGE-PGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 734

Query: 1572 PGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGE 1631
            PG  G  G +G  GP G QG  G  G +   G KG  G  GL G+KG  G  G  G KG+
Sbjct: 735  PGKEGQSGEKGALGPPGPQGPIGYPGPR---GVKGADGVRGLKGSKGEKGEDGFPGFKGD 791

Query: 1632 PGLPGDLGPVGQTGQR---------GRQGDSGIPG----YGQMGRKGVKGPRGFPGDAGQ 1678
             GL GD G VGQ G R         GR G +G PG     G+ G+ GV G  G+PG  G 
Sbjct: 792  MGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGP 851

Query: 1679 KGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
            KG  G PG PG  G KG RG+A   G  G  G RG  GP G RG +G  G+P
Sbjct: 852  KGSTGFPGFPGANGEKGARGVA---GKPGPRGQRGPTGPRGSRGARGPTGKP 900



 Score =  267 bits (683), Expect = 9e-71
 Identities = 157/363 (43%), Positives = 191/363 (52%), Gaps = 31/363 (8%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PGP G  GLQ + G  G KG  G  G  G PG  G  GPQG  G  G  G  G  G  
Sbjct: 1189 GFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSV 1248

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGD---PGSQGSPGSRGAPGQYGEKG-- 1509
            G  G KG  G+ G  G  GE G  G  G +GEKG+   PG+ G PG++G PG  G KG  
Sbjct: 1249 GGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP 1308

Query: 1510 ----FPGDPGNPGQNNNI--------KGQKGSKGEQGRQGRSGQKGVQGSPSSRG----- 1552
                FPGDPG PG+            KG+ G  G+ G  G SG+ G  G P  RG     
Sbjct: 1309 GPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAA 1368

Query: 1553 -SRGREGQRGLRGVSGEPGNPGPTGTLGAEG---LQGPQGSQGNPGRKGEKGSQGQKGPQ 1608
             + GR+G++G +G +G  G PG TG +G +G     GP+G +G PG  GE+G  G  G  
Sbjct: 1369 GAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQD 1428

Query: 1609 GSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKG 1668
            G PG MG  G  G  G  G KGE G PG +G +G  G++G +GD G+P  G  G  G KG
Sbjct: 1429 GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP--GTQGSPGAKG 1486

Query: 1669 PRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAG 1728
              G PG AG  G  G PG+PG  GPKG +G   + G  G++G  GLPGPPG  G  G   
Sbjct: 1487 DGGIPGPAGPLGPPGPPGLPGPQGPKGNKG---STGPAGQKGDSGLPGPPGSPGPPGEVI 1543

Query: 1729 QPV 1731
            QP+
Sbjct: 1544 QPL 1546



 Score =  259 bits (661), Expect = 3e-68
 Identities = 155/398 (38%), Positives = 186/398 (46%), Gaps = 65/398 (16%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G+PGP G  G    KG QG  G  G  G DG PG  G  G  G+KG  G PG  G  G  
Sbjct: 700  GLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYP 759

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGE------------------------KGDP 1490
            G  G KG  G  G+ G  GE+G  GFPG KG+                        KG  
Sbjct: 760  GPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRA 819

Query: 1491 GSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSS 1550
            G  G PG  G  G+ G+ G PG PG PG+    KG  G  G  G  G  G +GV G P  
Sbjct: 820  GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGP-KGSTGFPGFPGANGEKGARGVAGKPGP 878

Query: 1551 RGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQ-------------------- 1590
            RG RG  G RG RG  G  G PGP GT G +G  GP G +                    
Sbjct: 879  RGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGP 938

Query: 1591 -------GNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQ 1643
                   G+PG++GE G QG+ GP G  G++G +G TG  G +G++G PG PG  G  G 
Sbjct: 939  PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGL 998

Query: 1644 TGQRGRQGDSGIPG-YGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGG------------ 1690
             G  G++G  G PG  G  G+ G  G RGFPG+ G  G  G PG+ GG            
Sbjct: 999  PGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGS 1058

Query: 1691 PGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAG 1728
            PG +G  G A  +GL G  G +G PGP G++G  G  G
Sbjct: 1059 PGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG 1096



 Score =  254 bits (650), Expect = 6e-67
 Identities = 148/357 (41%), Positives = 181/357 (50%), Gaps = 27/357 (7%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PGP G  G     G +G  G RG  G  G PG++G  GPQG  G  G PG   ++G  
Sbjct: 1009 GDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG---ERGSA 1065

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDP 1514
            G +GP G  G  G  G  G  G  G PG KG +G  G  G  G  G PG  G  G PG+ 
Sbjct: 1066 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGED 1125

Query: 1515 GNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQ---GSPSSRGSRGREGQRGLRGVSGEPGN 1571
            G+ G+     GQKGSKG++G  G  G  G+Q   G+P   G  G  G RG +G+ G+ G+
Sbjct: 1126 GDKGEIGE-PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGD 1184

Query: 1572 ------PGPTGTLGAEGLQGPQGSQGN------------PGRKGEKGSQGQKGPQGSPGL 1613
                  PGP G +G +GL GP G +G             PG +G +G  G  GPQG PG 
Sbjct: 1185 EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGS 1244

Query: 1614 MGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFP 1673
            +G+ G  G  G  G+ G PG PG+ G  G  G+RG +G++G P  G  G  G KGP G  
Sbjct: 1245 VGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPP--GAAGPPGAKGPPGDD 1302

Query: 1674 GDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
            G  G  G +G PG PG PG  G  G     G KGE+G  G PGPPG  G  G  G P
Sbjct: 1303 GPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPP 1359



 Score =  250 bits (639), Expect = 1e-65
 Identities = 150/360 (41%), Positives = 182/360 (50%), Gaps = 24/360 (6%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAG---CPGAWGQ 1450
            PG PG  G RG   + G  G KG RG RG  G PG  GD G +G+ G  G    PG  G 
Sbjct: 591  PGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGP 650

Query: 1451 KGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGF 1510
            +GL G  G  G  G  G+ G+DG  G  G  G +GE G PG QG+PG +G PG  G  G 
Sbjct: 651  RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGP 710

Query: 1511 PGDPGNPGQNN--NIKGQKGSKGEQGRQGRSGQKGVQGS---------PSSRGSRGREGQ 1559
            PG+ G  G+     + G  G  G  G++G+SG+KG  G          P  RG +G +G 
Sbjct: 711  PGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGV 770

Query: 1560 RGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGS 1619
            RGL+G  GE G  G  G  G  GL+G +G  G  G +GE G +G KG  G  G  G  G 
Sbjct: 771  RGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQ 830

Query: 1620 TGRPGLLGKKGEPGLPGDLGPVGQT---------GQRGRQGDSGIPG-YGQMGRKGVKGP 1669
             G  G LG  G PG PG  GP G T         G++G +G +G PG  GQ G  G +G 
Sbjct: 831  AGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGS 890

Query: 1670 RGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQ 1729
            RG  G  G+ G  G  G  G PGP G RG     G  G  G +G PGPPG+ G+ G  GQ
Sbjct: 891  RGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQ 950



 Score =  250 bits (639), Expect = 1e-65
 Identities = 155/360 (43%), Positives = 188/360 (52%), Gaps = 30/360 (8%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGP---------QGDKGIAGC 1444
            PG PGP G  G    KG+ G KG +G  G DG  G  G  GP          GDKG  G 
Sbjct: 1074 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1133

Query: 1445 PGAWGQKGLKGFSGP------KGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGS 1498
            PG  G KG KG +GP      +G  G  GI G DGE G  G  G+ G+KGD G++G P  
Sbjct: 1134 PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFP-- 1191

Query: 1499 RGAPGQYGEKGFPGDPGNPGQNNNI--KGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGR 1556
             G PG  G +G PG PG  G+N ++   G  G  G +G QG +G  G QG P S GS G 
Sbjct: 1192 -GPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGG 1250

Query: 1557 EGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGR---KGEKGSQGQKGPQGSPGL 1613
             G++G  G +G PG PG  G  G +G +G +G  G PG     G KG  G  GP+G+PG 
Sbjct: 1251 VGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGP 1310

Query: 1614 MGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG----YGQMGRKGVKGP 1669
            +G  G  G PG  G  G+ G+ GD G  G  GQ G  G SG  G     G+ G  G  G 
Sbjct: 1311 VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGA 1370

Query: 1670 RGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQ 1729
             G  G+ G KG+ G  G PG  GP G +G A   G  G EG RG+PGP G++G+ G AGQ
Sbjct: 1371 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPA---GKPGPEGLRGIPGPVGEQGLPGAAGQ 1427



 Score =  249 bits (636), Expect = 2e-65
 Identities = 148/346 (42%), Positives = 183/346 (52%), Gaps = 18/346 (5%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG  G  G  G + M G  G KG RG  G  G PG +G  G +G +G  G PG  G +G 
Sbjct: 576  PGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGE 635

Query: 1454 KGFSGPKGGHGDDGIDGL---DGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGF 1510
             G  GP+G  G+ G  GL    G  G  G PG+ G  G PG +G+ G +G PG  G++G 
Sbjct: 636  DGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGN 695

Query: 1511 PGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPG 1570
            PG  G PG    I G  G KG QG+ G +G  G  G P   G  G+EGQ G +G  G PG
Sbjct: 696  PGPQGLPGPQGPI-GPPGEKGPQGKPGLAGLPGADGPP---GHPGKEGQSGEKGALGPPG 751

Query: 1571 NPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGK-- 1628
              GP G  G  G++G  G +G  G KGEKG  G  G +G  GL G +G  G+ G  G+  
Sbjct: 752  PQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDG 811

Query: 1629 ----KGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGN 1684
                KG  G  GD GP GQ G++G+ G  G+PGY   GR+G KG  GFPG  G  G+ G 
Sbjct: 812  PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGY--PGRQGPKGSTGFPGFPGANGEKGA 869

Query: 1685 PGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
             G+ G PGP+G RG     G +G  G+RG  G PG +G  G  G P
Sbjct: 870  RGVAGKPGPRGQRG---PTGPRGSRGARGPTGKPGPKGTSGGDGPP 912



 Score =  239 bits (609), Expect = 3e-62
 Identities = 151/407 (37%), Positives = 193/407 (47%), Gaps = 77/407 (18%)

Query: 1395 GIPGPHGTRGLQAMK----GSQG--------------------LKGSRGHRGEDGNPGVR 1430
            G+PGP GT  +   +    GS+G                    L+G  G  G  G PG  
Sbjct: 484  GLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPV 543

Query: 1431 GDTGPQGDKGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDP 1490
            G  G  G KG +G PG  G +G++G  GP G  G  G  G DG  G  G PG KG++G  
Sbjct: 544  GGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD 603

Query: 1491 GSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSS 1550
            G  G PG +G  G+ G +G PG PG+ G    ++G+ G  G +G  G +G +G+ G   +
Sbjct: 604  GLPGLPGDKGHRGERGPQGPPGPPGDDG----MRGEDGEIGPRGLPGEAGPRGLLGPRGT 659

Query: 1551 RGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGS 1610
             G+ G+ G  G+ G  G  GN GP G  G  G QG  G QG PG +G  G  G+KGPQG 
Sbjct: 660  PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 719

Query: 1611 PGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQ---------------------TGQRGR 1649
            PGL G  G+ G PG  GK+G+ G  G LGP G                       G +G 
Sbjct: 720  PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 779

Query: 1650 QGDSGIPGY----------------------GQMGRKGVKGPRGFP---GDAGQKGDIGN 1684
            +G+ G PG+                      G  G KG  GP G P   G AG+KG +G 
Sbjct: 780  KGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGV 839

Query: 1685 PGIPGGP---GPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAG 1728
            PG+PG P   GPKG  G     G  GE+G+RG+ G PG RG +G  G
Sbjct: 840  PGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTG 886



 Score =  188 bits (477), Expect = 7e-47
 Identities = 123/310 (39%), Positives = 155/310 (50%), Gaps = 8/310 (2%)

Query: 1423 EDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFSGP-KGGHGDDGIDGLDGEEGCHGFP 1481
            E+  PGV  +T    +  I G  GA+G+KG KG     + G   +G  G  G  G  G P
Sbjct: 399  EEFGPGVPAETDIT-ETSING-HGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPP 456

Query: 1482 GIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQ 1541
            G++G  G PG    PG RG PG+ G  G  G PG PG    +  + G  G +G    S Q
Sbjct: 457  GLQGPTGPPGD---PGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKG-PTISAQ 512

Query: 1542 KGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGS 1601
            +    +   +      G  G  G++G PG  G  G+ GA+G  G  G QG  G +G  G 
Sbjct: 513  EAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGP 572

Query: 1602 QGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG-YGQ 1660
             G+ G +G PG  G +G  G PG  G +G  GLPG  G  G  G+RG QG  G PG  G 
Sbjct: 573  TGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGM 632

Query: 1661 MGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQ 1720
             G  G  GPRG PG+AG +G +G  G PG PG  G  G+    G KG  G +G PGPPGQ
Sbjct: 633  RGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQ 692

Query: 1721 RGIKGMAGQP 1730
            +G  G  G P
Sbjct: 693  QGNPGPQGLP 702


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score =  271 bits (694), Expect = 5e-72
 Identities = 159/357 (44%), Positives = 189/357 (52%), Gaps = 29/357 (8%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PG  G  GL    G+ G  G +G  G  GNPG+ G+ GP G  G  G PG  G+KG 
Sbjct: 1109 PGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGK 1168

Query: 1454 KG---FSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGF 1510
             G     GP G  G+ G  G  G  G  G PG+ G+KGD G  G PG+ G PG  GE GF
Sbjct: 1169 PGQDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGF 1227

Query: 1511 ---------PGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRG 1561
                     PG PG+PG        +G KG  G QG  G+ G QG P   G  G  G  G
Sbjct: 1228 HGFPGVQGPPGPPGSPGP-----ALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGG 1282

Query: 1562 LRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTG 1621
            ++G  G PG PG  G  G +G QGP G QGNPGR G  G +G  G  G PG  G KG +G
Sbjct: 1283 IKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSG 1342

Query: 1622 RPGLLGKKGEPGLPGDLGPVGQTGQRGR----QGDSGIPGY-GQMGRKGV---KGPRGFP 1673
             PG  G +GEPGL G  GP G  G  G+    +GD+G PG  GQ G KG+   +GP+G P
Sbjct: 1343 VPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLP 1402

Query: 1674 GDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
            G  G  GD G  G+PG  G  G +G     GL G+ G+RGL GPPG  G++G  G P
Sbjct: 1403 GPTGPPGDPGRNGLPGFDGAGGRKG---DPGLPGQPGTRGLDGPPGPDGLQGPPGPP 1456



 Score =  254 bits (649), Expect = 8e-67
 Identities = 167/393 (42%), Positives = 194/393 (49%), Gaps = 63/393 (16%)

Query: 1396 IPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPG---VRGDTGPQGDKGIAGCPGAWGQKG 1452
            +PGP G  GL   KG+ G KG RG  G  G PG   + G  GP+GD G  G PG  G  G
Sbjct: 755  LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPG 814

Query: 1453 LKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQ--GSPGSRGAPGQYGEKGF 1510
            L G  G +G  G  GI G  G+ G HG PG KG+ G PG    G PG RG+PG  G  G 
Sbjct: 815  LPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGP 873

Query: 1511 PGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRG---VSG 1567
             G PG+PG    + G+ G+ G  G +G  G  G  G P   G  GR G  GL+G   + G
Sbjct: 874  IGPPGSPG----LPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQG 929

Query: 1568 EPGNPGPTGTLGAEG--------------LQGPQGSQGNPGRKGEKGSQGQKGPQGSPGL 1613
            +PG PGPTG  G++G              L G +G +G PG  G  G  G KG QG PG 
Sbjct: 930  QPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD 989

Query: 1614 MGAKGSTGRPGLLGK---KGEPGLPGDLGPVGQTGQRGRQGDSGIPG----YGQMGRKGV 1666
             G  G +G+PGL G    KG PGLPG  G +G  G +G  GD G PG     G  G  GV
Sbjct: 990  PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049

Query: 1667 KGPRGFPGDAGQKGDIGNPGI-----PGGPGPKG---------------------FRGLA 1700
             G  G PG  GQKGD G+PGI     PG PGPKG                       GL 
Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLP 1109

Query: 1701 LTVGLKGEEGSRGLPG---PPGQRGIKGMAGQP 1730
             T G KG+ G  G PG   PPG +GI G  G P
Sbjct: 1110 GTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNP 1142



 Score =  251 bits (642), Expect = 5e-66
 Identities = 164/415 (39%), Positives = 191/415 (46%), Gaps = 77/415 (18%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PG  G  G+   KG QGL G  G  G  G PG+ G  GP+G+ G+ G PG  G  GLK
Sbjct: 967  GEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLK 1026

Query: 1455 G------FSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEK 1508
            G      F GP+G  G  G  G+ G+ G  G PG KG+KGDPG   S G  G PG  GE 
Sbjct: 1027 GTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGIS-SIGLPGLPGPKGEP 1085

Query: 1509 GFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGE 1568
            G PG PGNPG   ++ G  G  G  G  G  GQ G+ G P + G  G +G  G  G  G 
Sbjct: 1086 GLPGYPGNPGIKGSV-GDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGL 1144

Query: 1569 PGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKG-----------PQGSPGLMGAK 1617
            PG PGP G  G  G  GP G +G PG+ G  G  GQKG           P G PGL G K
Sbjct: 1145 PGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQK 1204

Query: 1618 GS------TGRPGLLGKKGEPGL------------PGDLGPV--GQTGQRGRQGDSGIPG 1657
            G        G PGL G KGEPG             PG  GP   G  G  G QG  G PG
Sbjct: 1205 GDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPG 1264

Query: 1658 YGQMGRKGVKGPRGFPGDAGQKGDIGNPG------------------------------- 1686
            +   G  G +GP G PG+ G KG+ GNPG                               
Sbjct: 1265 F--QGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGM 1322

Query: 1687 -----IPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCD 1736
                 +PG PG  G +G +   G  G EG  GL GPPG  G+ G +GQ +  + D
Sbjct: 1323 KGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGD 1377



 Score =  251 bits (641), Expect = 6e-66
 Identities = 157/379 (41%), Positives = 186/379 (49%), Gaps = 46/379 (12%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRG------EDGNPGVRGDTGPQGDKGIAGCPGA 1447
            PG+PG  G  G    KG  G+ G  G  G        G PG++GD G QG  G+ G  G 
Sbjct: 880  PGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGE 939

Query: 1448 WGQKGLKGFSGP-----------KGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSP 1496
             G KG  G  GP           KG  G+ G+ G+ G  G  G+ G+ G+ G PG  G P
Sbjct: 940  KGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQP 999

Query: 1497 GSRGAPGQYGEKGFPGDPG---NPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGS 1553
            G  G PG  G  G PG PG    PG    I G  G  G QG +G  G  GV G P S G 
Sbjct: 1000 GLPGPPGPKGNPGLPGQPGLIGPPGLKGTI-GDMGFPGPQGVEGPPGPSGVPGQPGSPGL 1058

Query: 1554 RGREGQRGLRGVS--GEPGNPGPTGTLGAEGLQGP---QGSQGNPGRKGEKGSQGQKGPQ 1608
             G++G +G  G+S  G PG PGP G  G  G  G    +GS G+PG  G  G+ G KG  
Sbjct: 1059 PGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQP 1118

Query: 1609 GSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVG---------QTGQRGRQGDSGIPG-Y 1658
            G PG  G  G  G  G+ G  G PGLPG+ GPVG           G++G+ G  GIPG  
Sbjct: 1119 GLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPA 1178

Query: 1659 GQMGRKGVKG-----PRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRG 1713
            GQ G  G  G     P G PG +GQKGD G PGIPG PG  G +G     G  G  G +G
Sbjct: 1179 GQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG---EPGFHGFPGVQG 1235

Query: 1714 LPGPPGQRG--IKGMAGQP 1730
             PGPPG  G  ++G  G P
Sbjct: 1236 PPGPPGSPGPALEGPKGNP 1254



 Score =  246 bits (629), Expect = 2e-64
 Identities = 158/404 (39%), Positives = 184/404 (45%), Gaps = 71/404 (17%)

Query: 1395 GIPGPHGTRGLQAMKGSQG-----LKGSRGHRGEDGNPGVRGDTGPQG----------DK 1439
            G PGP G  G +  KG +G     + G  G  G+ G PG+ G  GP G          + 
Sbjct: 394  GPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEP 453

Query: 1440 GIAGCPGAWGQKGLKGFSGPKGGHGDD----------------GIDGLDGEEGCHGFPGI 1483
            G  G PG+ G KGL+G  G KG  GD                 G+ GL G  G  GFPG 
Sbjct: 454  GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQ 513

Query: 1484 KGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKG 1543
            KGEKG  G+ G  G  G PG  G  GFPG  G PG      G KG KGE G  G  G  G
Sbjct: 514  KGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573

Query: 1544 VQGSPSSRGSRGREGQRG------LRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKG 1597
            + G+P   G  G  G +G       +G  G PGNPG  G  G  G  GP G  G PG  G
Sbjct: 574  LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPGPVG 632

Query: 1598 EKGSQGQKGPQGSPGLMGAKGSTGR----------PGLLGKKGEPGLPGDLGPVGQTGQR 1647
            EKG QG  G  G PG+ G KG  G+          PG  G+ G+ GLPGD G  GQ G  
Sbjct: 633  EKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLP 692

Query: 1648 GRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPG--------------------- 1686
            G  G  G PG   +G  G  GP+GFPG  G  G  G PG                     
Sbjct: 693  GIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPG 752

Query: 1687 --IPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAG 1728
              +PG PGP G  G    +G KG+ G  G PGPPG+ G+ G+ G
Sbjct: 753  FALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPG 796



 Score =  246 bits (627), Expect = 3e-64
 Identities = 158/370 (42%), Positives = 179/370 (48%), Gaps = 28/370 (7%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G+PGP G +G   + G  G  G+ G  G +G PG  G  GP+G+ G A  PG  G  GL 
Sbjct: 707  GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFA-LPGPPGPPGLP 765

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQ--YGEKGFPG 1512
            GF G  G  GD G  G  G  G  G  G+ G KGD G  G PG  G PG    G +G PG
Sbjct: 766  GFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPG 825

Query: 1513 DPGNPGQN-----NNIKGQKGSKGEQGRQ--GRSGQKGVQGSPSSRGSRGREGQRGLRGV 1565
             PG PG       + I G+KG  G  G    G  G++G  G P + G  G  G  GL G 
Sbjct: 826  PPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGK 885

Query: 1566 SGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGL---MGAKGSTGR 1622
            +G  G PG  G +G  G  GP G  G PGR G  G +G  G QG PGL    G KGS G 
Sbjct: 886  AGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGE 945

Query: 1623 PGL--------------LGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGVK 1667
            PGL               G+KGEPGLPG  G  G  G +G  GD G PG  GQ G  G  
Sbjct: 946  PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPP 1005

Query: 1668 GPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMA 1727
            GP+G PG  GQ G IG PG+ G  G  GF G     G  G  G  G PG PG  G KG  
Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065

Query: 1728 GQPVYSQCDL 1737
            G P  S   L
Sbjct: 1066 GDPGISSIGL 1075



 Score =  243 bits (621), Expect = 1e-63
 Identities = 167/468 (35%), Positives = 198/468 (42%), Gaps = 128/468 (27%)

Query: 1391 CKCPGIPGPHGTRGLQAMKGSQGLKG---------SRGHRGEDGNPGVRGDTGPQGDKGI 1441
            C C GI G  G RG   ++G  GL G          RG +G+DG PG  G  G +G  G+
Sbjct: 38   CDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGL 97

Query: 1442 AGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGA 1501
             G PG  G  G+ G  G  G  G  G +G  GE G  G PG  G +G PG  G PG +G 
Sbjct: 98   PGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGE 157

Query: 1502 PGQY------GEKGFPGDPGNPG------------------------------------- 1518
            PG        G KG PG PG PG                                     
Sbjct: 158  PGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGN 217

Query: 1519 QNNNIKGQKGSKGEQGRQGRSG----------------QKGVQGSPSSR----------- 1551
               N +G KG KGEQG QG  G                QKG QG P  R           
Sbjct: 218  MGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP 277

Query: 1552 -----GSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKG 1606
                 G +G +G++G  G  G+PG  G  G  G  GL G  G  G PGR GEKG +G  G
Sbjct: 278  PGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTG 337

Query: 1607 PQGSPGL----------MGAKGSTGRPGLLGKKGE---------PGLP--------GDLG 1639
            P G PGL          +G KG+ G PGL G+KGE         PGLP        G  G
Sbjct: 338  PPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG 397

Query: 1640 PVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIG----------NPGIPG 1689
            P G  G+RG++GD G PG    G  G+ G  G PG  G  G  G           PG PG
Sbjct: 398  PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG 457

Query: 1690 GPGPKGFRGLALTVGLKGEEG-------SRGLPGPPGQRGIKGMAGQP 1730
             PG  G +GL    G+KG++G         G+ GPPGQ G+ G+ G P
Sbjct: 458  PPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPP 505



 Score =  241 bits (614), Expect = 9e-63
 Identities = 152/373 (40%), Positives = 180/373 (48%), Gaps = 41/373 (10%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHR-------GEDGNPGVRGDTGPQGDKGIAGCPG 1446
            PG PGP G+ G + ++G QG+KG +G         G  G PG  G  G  G  G  G PG
Sbjct: 453  PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512

Query: 1447 AWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHG-------FPGIKGEKGDPGSQGSPGSR 1499
              G+KG  G +GPKG  G  G  G  G  G  G       FPG+KG+KG+ GS G+PG  
Sbjct: 513  QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572

Query: 1500 GAPGQYGEKGFPGDPGNPGQNNNI--KGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGRE 1557
            G PG  G+ G PG PG  G+   I  KG++G  G  G  G  G  G  G P   G  G  
Sbjct: 573  GLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPGPV 631

Query: 1558 GQRGLRGVSGEPGNPGPTGTLGAEGLQ----GPQGSQGNPGRKGEKGSQGQKGPQGSPGL 1613
            G++G++GV+G PG PG  G  G  G      G  G  GNPGR G+ G  G  G  G PGL
Sbjct: 632  GEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGL 691

Query: 1614 MGAKGSTGRPGLLG-----------------KKGEPGLPGDLGPVGQTGQRGRQGDSGIP 1656
             G  GS G PG+ G                   G PG PG +G  G  G  G  G  G P
Sbjct: 692  PGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEP 751

Query: 1657 GYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPG 1716
            G+   G  G  G  GF G  G KGD G PG PG PG  G  GL    G KG+ G  G PG
Sbjct: 752  GFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP---GPKGDVGPNGQPG 808

Query: 1717 PPGQRGIKGMAGQ 1729
            P G  G+ G+  Q
Sbjct: 809  PMGPPGLPGIGVQ 821



 Score =  233 bits (595), Expect = 1e-60
 Identities = 156/385 (40%), Positives = 180/385 (46%), Gaps = 57/385 (14%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PGP G RG   + G  G  G  G  G DG PG +G  G  G KG  G PG+ G  GL
Sbjct: 83   PGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGL 142

Query: 1454 KGFSGPKGGHGDDGIDG------LDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGE 1507
            +G  GP G  G  G  G      L G +G  G+PG  G +G PG  G PG  G PG  G 
Sbjct: 143  QGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGL 202

Query: 1508 KGFPGDPGNPGQNNNI----KGQKGSKGEQGRQGRSG----------------QKGVQGS 1547
             G PG PG PG   N+    +G KG KGEQG QG  G                QKG QG 
Sbjct: 203  MGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGL 262

Query: 1548 PSSRG----------------SRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQG 1591
            P  RG                 +G +G++G  G  G+PG  G  G  G  GL G  G  G
Sbjct: 263  PGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPG 322

Query: 1592 NPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQG 1651
             PGR GEKG +G  GP G PGL+  +  TG    +G+KG  GLPG  G  G+ G  G QG
Sbjct: 323  EPGRDGEKGQKGDTGPPGPPGLVIPRPGTGIT--IGEKGNIGLPGLPGEKGERGFPGIQG 380

Query: 1652 DSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGS 1711
              G+PG       G  GP GFPG+ GQKGD G PGI   PGP G             +G 
Sbjct: 381  PPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGI-SIPGPPGL------------DGQ 427

Query: 1712 RGLPGPPGQRGIKGMAGQPVYSQCD 1736
             G PG PG  G  G    P    C+
Sbjct: 428  PGAPGLPGPPGPAGPHIPPSDEICE 452



 Score =  221 bits (562), Expect = 9e-57
 Identities = 162/420 (38%), Positives = 188/420 (44%), Gaps = 88/420 (20%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGV-------------RGDTGPQGDKG 1440
            PG+PGP G  GL   +G +G KG +G +G  G PG              +GD G  GD+G
Sbjct: 209  PGLPGPKGNMGLN-FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRG 267

Query: 1441 IAGCPGAWGQKGLKGFS-GPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSR 1499
              G PG  G  G  G   G KG  G+ G  G  G++G +G PGI G  GDPG  G PG  
Sbjct: 268  PPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRD 327

Query: 1500 GAPGQYGEKGFPGDPG----NPGQ--------NNNIKGQKGSKGEQGRQGRSGQKGVQGS 1547
            G  GQ G+ G PG PG     PG         N  + G  G KGE+G  G  G  G+ G 
Sbjct: 328  GEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP 387

Query: 1548 PSSR-----------GSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQG----- 1591
            P +            G RG++G  G  G+S  PG PG  G  GA GL GP G  G     
Sbjct: 388  PGAAVMGPPGPPGFPGERGQKGDEGPPGIS-IPGPPGLDGQPGAPGLPGPPGPAGPHIPP 446

Query: 1592 -----NPGRKGEKGSQGQKGPQGSPGLMGAKGST----------------GRPGLLGKKG 1630
                  PG  G  GS G KG QG  G+ G KG T                G PGL G  G
Sbjct: 447  SDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPG 506

Query: 1631 EPGLPGDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGVKGPRG----FPGDAGQKGDIGNP 1685
              G PG  G  GQ G  G +G  GIPG  G  G  G KG  G    FPG  G KG++G+P
Sbjct: 507  SLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSP 566

Query: 1686 G---------------IPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
            G               +PG PGPKG  G    +  KGE G  G PG PG  G  G  G P
Sbjct: 567  GAPGLPGLPGTPGQDGLPGLPGPKGEPG---GITFKGERGPPGNPGLPGLPGNIGPMGPP 623



 Score =  193 bits (490), Expect = 2e-48
 Identities = 126/334 (37%), Positives = 151/334 (45%), Gaps = 70/334 (20%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKG- 1452
            PG PGP G +G+    G+ GL G  G  G  G+PG  G  G +G  G  G PG  GQKG 
Sbjct: 1124 PGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGE 1183

Query: 1453 -------------LKGFSGPKGGHG------DDGIDGLDGEEGCHGFPGIKGEKGDPGS- 1492
                         L G SG KG  G      + G+ G  GE G HGFPG++G  G PGS 
Sbjct: 1184 PGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSP 1243

Query: 1493 -------QGSPGSRGAPGQYGEKGFPGDPGNPGQ--NNNIKGQKGSKGEQGRQGRSGQKG 1543
                   +G+PG +G PG+ G +G PG  G PG   N  IKG+KG+ G+ G  G  G KG
Sbjct: 1244 GPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKG 1303

Query: 1544 VQGSPSSRGSRGR---------------------------------EGQRGLRGVSGEPG 1570
             QG P  +G+ GR                                 EG+ GL G  G PG
Sbjct: 1304 DQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPG 1363

Query: 1571 NPGPTGT-------LGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRP 1623
             PGP+G         G  G+ G  G +G PG +G +G  G  GP G PG  G  G  G  
Sbjct: 1364 LPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAG 1423

Query: 1624 GLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG 1657
            G  G  G PG PG  G  G  G  G QG  G PG
Sbjct: 1424 GRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1457



 Score =  159 bits (401), Expect = 4e-38
 Identities = 93/211 (44%), Positives = 106/211 (50%), Gaps = 5/211 (2%)

Query: 1516 NPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPT 1575
            +PG   +  G KG KGE+G  G  G  G+ G P   G  G  GQ+G  G+ G PG  G  
Sbjct: 33   SPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIR 92

Query: 1576 GTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLP 1635
            G  G  G  G  G  G PG  G  G QG  G  G+ G  G  GS G PGL G  G PG+P
Sbjct: 93   GPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIP 152

Query: 1636 GDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGVKGPRGFPGDAGQKGD---IGNPGIPGGP 1691
            G  G  G        G  G PGY G  G +G+ GP G PG  G  G    +G PG PG P
Sbjct: 153  GMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLP 212

Query: 1692 GPKGFRGLALTVGLKGEEGSRGLPGPPGQRG 1722
            GPKG  GL    G KGE+G +GL GPPG  G
Sbjct: 213  GPKGNMGLNFQ-GPKGEKGEQGLQGPPGPPG 242



 Score =  157 bits (396), Expect = 2e-37
 Identities = 91/229 (39%), Positives = 118/229 (51%), Gaps = 11/229 (4%)

Query: 1394 PGIPGP--HGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQK 1451
            PG PGP   G +G    +G  G  G +G  G +G PG+ G+ G +G+KG  G PG  G  
Sbjct: 1240 PGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLP 1299

Query: 1452 GLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFP 1511
            GLKG  GP G  G+ G  GL+G +G  G PG+ G  G  G  G PGS G  G+ G  G P
Sbjct: 1300 GLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPP 1359

Query: 1512 GDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGN 1571
            G PG PG +      KG          +G  G+ G P  +G  G +G +GL G +G PG+
Sbjct: 1360 GPPGLPGPSGQSIIIKGD---------AGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGD 1410

Query: 1572 PGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGST 1620
            PG  G  G +G  G +G  G PG+ G +G  G  GP G  G  G  G++
Sbjct: 1411 PGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTS 1459



 Score =  105 bits (263), Expect = 4e-22
 Identities = 64/141 (45%), Positives = 71/141 (50%), Gaps = 10/141 (7%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDG---NPGVRGDTGPQGD----KGIAGCPGA 1447
            G PG  G  G   MKG  G+ GS G  GE G    PG  G  GP G     KG AG PG 
Sbjct: 1324 GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGI 1383

Query: 1448 WGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKG---EKGDPGSQGSPGSRGAPGQ 1504
             GQ GLKG  GP+G  G  G  G  G+ G +G PG  G    KGDPG  G PG+RG  G 
Sbjct: 1384 PGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGP 1443

Query: 1505 YGEKGFPGDPGNPGQNNNIKG 1525
             G  G  G PG PG ++   G
Sbjct: 1444 PGPDGLQGPPGPPGTSSVAHG 1464



 Score =  105 bits (262), Expect = 6e-22
 Identities = 61/128 (47%), Positives = 71/128 (55%), Gaps = 11/128 (8%)

Query: 1612 GLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRG 1671
            G+ G KG  G PGL   +G PGLPG  GP G  G RG++GD GIPG    G KG++GP G
Sbjct: 42   GIKGEKGERGFPGL---EGHPGLPGFPGPEGPPGPRGQKGDDGIPG--PPGPKGIRGPPG 96

Query: 1672 FPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPG------PPGQRGIKG 1725
             PG  G  G  G PG  G PGP+G  G   T G +G  GS G PG      PPG  G+KG
Sbjct: 97   LPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKG 156

Query: 1726 MAGQPVYS 1733
              G  + S
Sbjct: 157  EPGSIIMS 164



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 41/94 (43%), Positives = 46/94 (48%), Gaps = 10/94 (10%)

Query: 1644 TGQRGRQGDSGIPGY-GQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALT 1702
            +G +G +G+ G PG  G  G  G  GP G PG  GQKGD    GIPG PGPKG RG    
Sbjct: 41   SGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGD---DGIPGPPGPKGIRGPP-- 95

Query: 1703 VGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCD 1736
                G  G  G PG PG  G  G  G      C+
Sbjct: 96   ----GLPGFPGTPGLPGMPGHDGAPGPQGIPGCN 125


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  271 bits (692), Expect = 8e-72
 Identities = 154/352 (43%), Positives = 183/352 (51%), Gaps = 25/352 (7%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTG------PQGDKGIAGCPGA 1447
            PG PGP G +GL    G +G  G  G  G  G PG RG +G      PQG  G  G PGA
Sbjct: 1221 PGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGA 1280

Query: 1448 WGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGE 1507
             G+KG  G +G  G  G+ G  G  GE G  G  G  G  G PG +G PG  G  G  G 
Sbjct: 1281 VGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGP 1340

Query: 1508 KGFPGDPGNPGQ--------------NNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGS 1553
             GFPGDPG PG+              ++   GQ GS G  G  G SG  G +G P   G 
Sbjct: 1341 VGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGP 1400

Query: 1554 RGREGQRGLRG---VSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGS 1610
             GR+G++G +G   + G PG  GP G  GA G  GP G +G PG  GE+G  G  GP G 
Sbjct: 1401 EGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGP 1460

Query: 1611 PGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPR 1670
            PG MG  G  G  G  G KGE G PG +G +G  G++G +GD G+P  G  G  G KG +
Sbjct: 1461 PGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLP--GPQGSSGPKGEQ 1518

Query: 1671 GFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRG 1722
            G  G +G  G  G PG+PG PGPKG +G +   G KGE G  G PGPPG  G
Sbjct: 1519 GITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPG 1570



 Score =  269 bits (687), Expect = 3e-71
 Identities = 157/369 (42%), Positives = 186/369 (50%), Gaps = 37/369 (10%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PG  G +G     G  G  G +G RG  G PG RG  GP G +G  G  G  G+ G 
Sbjct: 873  PGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGP 932

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD 1513
            KG SG  G  G  G  G +G +G  GFPG KG  G PG  G PG    PGQ GE GF G 
Sbjct: 933  KGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGH---PGQRGETGFQGK 989

Query: 1514 PGNPGQNNNI-----------------KGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGR 1556
             G PG    +                  G  G  GEQG  G +G++G +G P   G  G+
Sbjct: 990  TGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGK 1049

Query: 1557 EGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGS---------QGQKGP 1607
            +G  GLRG  G+ G PGP G LG +G +GP G  G  G  GE+G           G+ GP
Sbjct: 1050 DGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGP 1109

Query: 1608 QGSPGLMGAKGSTGRPGLLGK------KGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQM 1661
            QG PG  G KG+ G  G  G       +G  GLPG  GPVG  G+ G +G+ G P  GQ 
Sbjct: 1110 QGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEP--GQK 1167

Query: 1662 GRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQR 1721
            G KG KG +G PG  G +G IG PG  G  G  G RG     G KG+EG RG PGPPG  
Sbjct: 1168 GSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPV 1227

Query: 1722 GIKGMAGQP 1730
            G++G+ G P
Sbjct: 1228 GLQGLPGPP 1236



 Score =  268 bits (686), Expect = 4e-71
 Identities = 150/350 (42%), Positives = 193/350 (55%), Gaps = 26/350 (7%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PGP G +G     G +GLKG++G +GEDG PG +GD G +GD+G  G PG  G+ G +
Sbjct: 787  GYPGPRGVKGAD---GIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPE 843

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDP 1514
            G  G  G +GD G  G  GE+G  G PG+ G  G  G +GS G  G PG  GEKG  G P
Sbjct: 844  GPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTP 903

Query: 1515 GNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGP 1574
            G P       G +G +G  G +G  G +G+ G P  +G+ G +G  G  G  G  G  GP
Sbjct: 904  GKP-------GPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGP 956

Query: 1575 TGTLGAEGLQGPQGSQ---GNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGE 1631
            TG  G +G  GP G     G+PG++GE G QG+ GP G PG++G +G TG  G +G++G 
Sbjct: 957  TGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGH 1016

Query: 1632 PGLPGDLGPVGQTGQRGRQGDSGIPG-YGQMGRKGVKGPRGFPGDAGQKGDI------GN 1684
            PG PG  G  G  G  G++G  G PG  G  G+ G  G RGFPGD G  G +      GN
Sbjct: 1017 PGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGN 1076

Query: 1685 PGIPGGPGP------KGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAG 1728
             G PG PGP      +G  G A  +G+ G  G +G PGP G++G  G  G
Sbjct: 1077 EGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKG 1126



 Score =  266 bits (680), Expect = 2e-70
 Identities = 157/367 (42%), Positives = 185/367 (50%), Gaps = 36/367 (9%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PGP G RG        G +G RG RG  G PG +G++G  G  G  G  G  G +G 
Sbjct: 903  PGKPGPRGQRG------PTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGP 956

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQ---YGEKGF 1510
             GF GPKG  G  G DGL G  G  G  G +G+ G PG  G  G +G  G+    GE+G 
Sbjct: 957  TGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGH 1016

Query: 1511 PGDPGNPGQNN-----NIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGV 1565
            PG PG PG+         +G KG  G  G  G+ G  G++G P  RG  G  G  GL+G 
Sbjct: 1017 PGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGN 1076

Query: 1566 SGEPGNPGPTGTLGAEG---------LQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGA 1616
             G PG PGP G+ G  G         + G  G QG PG  GEKG+ G+KGPQG  G  G 
Sbjct: 1077 EGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGL 1136

Query: 1617 KGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG-------------YGQMGR 1663
            +G  G PG  G  G PG  GD G +G+ GQ+G +GD G  G              G  G 
Sbjct: 1137 QGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGA 1196

Query: 1664 KGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGI 1723
             G  GPRG  G  GQKGD G  G PG PGP G +GL    G KGE G  G  GPPG  G 
Sbjct: 1197 DGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGP 1256

Query: 1724 KGMAGQP 1730
            +G +G P
Sbjct: 1257 RGPSGAP 1263



 Score =  265 bits (678), Expect = 3e-70
 Identities = 156/363 (42%), Positives = 186/363 (51%), Gaps = 28/363 (7%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKG---IAGCPGAWGQ 1450
            PG  GP G RG+Q   G  G  G RG  G DG  G+ G TGP+GD+G   +AG PG  G 
Sbjct: 585  PGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGH 644

Query: 1451 KGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPG------IKGEKGDPGSQGSPGSRGAPGQ 1504
            +G  G SGP G  GDDG  G DGE G  G PG      + G KG PG  G PG  G  GQ
Sbjct: 645  RGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQ 704

Query: 1505 YGEKGF---PGDPGNPGQNNNI--------------KGQKGSKGEQGRQGRSGQKGVQGS 1547
             G KG     G+PG PGQ  N                G+KG  G+ G  G  G  G  G 
Sbjct: 705  PGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGH 764

Query: 1548 PSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGP 1607
            P   G  G +G +G  G  G  G PGP G  GA+G++G +G++G  G  G  G +G  G 
Sbjct: 765  PGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGI 824

Query: 1608 QGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVK 1667
            +G  G +G  G  G  G  G KG  G  GD GP+G  G++G+ G  G+PGY   GR+G K
Sbjct: 825  KGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGY--PGRQGPK 882

Query: 1668 GPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMA 1727
            G  GFPG  G  G+ G  G PG PGP+G RG     G +G  G  G PGP G  G  G A
Sbjct: 883  GSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPA 942

Query: 1728 GQP 1730
            G P
Sbjct: 943  GPP 945



 Score =  255 bits (652), Expect = 3e-67
 Identities = 150/363 (41%), Positives = 180/363 (49%), Gaps = 30/363 (8%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G  GP G  G +   G  G KGS+G +GE G PG  G  GP G  G +G  G  G +G +
Sbjct: 1147 GPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQ 1206

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDP 1514
            G  G KG  G  G  G  G  G  G PG  GEKG+ G  G  G  G PG  G  G PG  
Sbjct: 1207 GLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGAD 1266

Query: 1515 GNPGQNNNI--KGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNP 1572
            G  G    I   G  G KGE G  G  G  G  G P  +G RG +G+ G  G +G PG  
Sbjct: 1267 GPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPK 1326

Query: 1573 GPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGP------QGSPGLMGAKGSTGRPGLL 1626
            GP G  G +G  GP G  G+PG  GE G  GQ GP       G PG  G+ G TG PG  
Sbjct: 1327 GPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPS 1386

Query: 1627 GKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG----------YGQMGRKGVKGPRGFPGDA 1676
            G  G+ G PG  GP G+ G++G +G++G+ G           G  G+ G  G RG PG  
Sbjct: 1387 GPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPV 1446

Query: 1677 GQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSR---------GLPGPPGQRGIKGMA 1727
            G++G  G+PG  G PGP G  GL    GLKG+ G +         GL GPPG++G KG  
Sbjct: 1447 GEQGLPGSPGPDGPPGPMGPPGLP---GLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDR 1503

Query: 1728 GQP 1730
            G P
Sbjct: 1504 GLP 1506



 Score =  252 bits (644), Expect = 3e-66
 Identities = 159/376 (42%), Positives = 191/376 (50%), Gaps = 47/376 (12%)

Query: 1398 GPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQ------K 1451
            GP G  GL    G  G  GS G +GE G+ G +G  G QG  G AG PG  G+      +
Sbjct: 559  GPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGAR 618

Query: 1452 GLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKG---------EKGDPGS---QGSPGSR 1499
            G+ G +GPKG  G DG+ GL GE+G  G PG  G         E+GD G    +G PG  
Sbjct: 619  GMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEP 678

Query: 1500 GAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQ 1559
            G  G  G KG PG PG PG    + GQ G KG  G QG  G  G QG+P ++G  G +G 
Sbjct: 679  GPRGLLGPKGPPGPPGPPGV-TGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGA 737

Query: 1560 RGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGS 1619
             G  G  G  G PG  G  GA+G  G  G +G PG KG +G  G +GP G PG  G KG+
Sbjct: 738  IGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGA 797

Query: 1620 TGRPGLLGKKGE------PGLPGDLGPVGQTGQ---------------RGRQGDSGIPG- 1657
             G  GL G KGE      PG  GD+G  G  G+               +GR G +G PG 
Sbjct: 798  DGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGP 857

Query: 1658 ---YGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGL 1714
                G+ G+ GV G  G+PG  G KG IG PG PG  G KG RG   T G  G  G RG 
Sbjct: 858  LGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRG---TPGKPGPRGQRGP 914

Query: 1715 PGPPGQRGIKGMAGQP 1730
             GP G+RG +G+ G+P
Sbjct: 915  TGPRGERGPRGITGKP 930



 Score =  252 bits (643), Expect = 4e-66
 Identities = 155/377 (41%), Positives = 186/377 (49%), Gaps = 44/377 (11%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGV------RGDTGPQGDKGIAGCPGAW 1448
            G PGP G  GL    G +G  G +G  G  G PGV       G+TGP G++G  G PG  
Sbjct: 964  GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPP 1023

Query: 1449 GQKGLKGFSGPKGGHGDDGIDGL---DGEEGCHGFPGIKG---------------EKGDP 1490
            G++GL G +G +G  GD G  GL   DG  G  GFPG +G                 G P
Sbjct: 1024 GEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPP 1083

Query: 1491 GSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQG---- 1546
            G  GSPG RG  G  G  G PG PG  G      G+KG+ GE+G QG +G+ G+QG    
Sbjct: 1084 GPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPA-GEKGAPGEKGPQGPAGRDGLQGPVGL 1142

Query: 1547 -----------SPSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGR 1595
                           +G  G  GQ+G +G  GE G PGPTG  G  G  GP G+ G PG 
Sbjct: 1143 PGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGP 1202

Query: 1596 KGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGI 1655
            +G++G  GQKG +G  G  G  G  G  GL G  GE G  GD+G +G  G  G +G SG 
Sbjct: 1203 RGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGA 1262

Query: 1656 PGY-GQMGRKGVKGPRGFPGDAGQKGDIGNPGIP---GGPGPKGFRGLALTVGLKGEEGS 1711
            PG  G  G  G  G  G  G+ G+ G+ G PG+P   G PGPKG RG     G  G  G 
Sbjct: 1263 PGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGP 1322

Query: 1712 RGLPGPPGQRGIKGMAG 1728
             G  GPPG  G KG  G
Sbjct: 1323 PGPKGPPGDDGPKGSPG 1339



 Score =  222 bits (565), Expect = 4e-57
 Identities = 142/380 (37%), Positives = 167/380 (43%), Gaps = 54/380 (14%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRG---EDGNPGVRGDT------------------ 1433
            G+PGP GT G     G  G +G  G  G    DG PG  G                    
Sbjct: 478  GLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGP 537

Query: 1434 ---------------------GPQGDKGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLD 1472
                                 GP G  G+ G PG  G  G  G  G  G  G  G  G+ 
Sbjct: 538  MVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQ 597

Query: 1473 GEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGE 1532
            G  G  G PG +G  G  G++G PG  G  G  G  G  G PG  G     +G  G  G 
Sbjct: 598  GPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGH----RGDPGPSGP 653

Query: 1533 QGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGN 1592
             G  G  G++G  G    RG  G  G RGL G  G PG PGP G  G +G  GP+G+ G 
Sbjct: 654  PGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGP 713

Query: 1593 PGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGD 1652
             G  G  G QG  G QG PG  GA G  G  G LGK G PG+PG  GP G  G+ G  G+
Sbjct: 714  QGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGE 773

Query: 1653 SGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPK---GFRGLALTVGLKGEE 1709
             G    GQ G  G +GP G+PG  G KG  G  G+ G  G K   GF G    +G+KG+ 
Sbjct: 774  KG----GQ-GPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDR 828

Query: 1710 GSRGLPGPPGQRGIKGMAGQ 1729
            G  G PGP G+ G +G  G+
Sbjct: 829  GEIGPPGPRGEDGPEGPKGR 848



 Score =  215 bits (547), Expect = 5e-55
 Identities = 131/366 (35%), Positives = 172/366 (46%), Gaps = 58/366 (15%)

Query: 1412 QGLKGSRGHRGEDGNPG-------VRGDTGPQGDKGIAGCPGAWGQKGLKGFSGPKGGHG 1464
            +G+ G RG +G+ G P        + G  GP+G  G+ G PG  G  G  G  G +G  G
Sbjct: 443  EGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPG 502

Query: 1465 DDGIDGLDGEEGCHG--------FPG----------------------------IKGEKG 1488
              G+ G DG  G  G        F G                            ++G  G
Sbjct: 503  RPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAG 562

Query: 1489 DPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSP 1548
              G  G PG  G PG  G KG PGD G  G    ++G  G  G+ GR+GR+G  G +G P
Sbjct: 563  PMGLTGRPGPVGPPGSGGLKGEPGDVGPQGP-RGVQGPPGPAGKPGRRGRAGSDGARGMP 621

Query: 1549 SSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQ 1608
               G +G  G  GL G+ GE G+ G  G  G  G  G  G +G+ G  G +G  G+ GP+
Sbjct: 622  GQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPR 681

Query: 1609 GSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKG 1668
            G  G  G  G  G PG+ G  G+PG  G++GP G+ G  G+QG+         G +G+ G
Sbjct: 682  GLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNP--------GAQGLPG 733

Query: 1669 PRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGP------PGQRG 1722
            P+G  G  G+KG +G PG+PG PG  G  G     G  GE+G +G PGP      PG RG
Sbjct: 734  PQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRG 793

Query: 1723 IKGMAG 1728
            +KG  G
Sbjct: 794  VKGADG 799



 Score =  210 bits (535), Expect = 1e-53
 Identities = 136/373 (36%), Positives = 174/373 (46%), Gaps = 37/373 (9%)

Query: 1395 GIPGPHGTRGLQAMKGS-------QGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGA 1447
            GI GP G +G +            +G  G  G  G  G PG  G TG  GD G  G PG 
Sbjct: 444  GIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGR 503

Query: 1448 WGQKGLKGFSGPKG----------GHGDDGIDG--LDGEEGC------HGFPGIKGEKGD 1489
             G  G  G  GP G          G GD G  G  +  +E             ++G  G 
Sbjct: 504  PGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGP 563

Query: 1490 PGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPS 1549
             G  G PG  G PG  G KG PGD G  G    ++G  G  G+ GR+GR+G  G +G P 
Sbjct: 564  MGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRG-VQGPPGPAGKPGRRGRAGSDGARGMPG 622

Query: 1550 SRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQG 1609
              G +G  G  GL G+ GE G+ G  G  G  G  G  G +G+ G  G +G  G+ GP+G
Sbjct: 623  QTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRG 682

Query: 1610 SPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGP 1669
              G  G  G  G PG+ G  G+PG  G++GP G+ G  G+QG+ G         +G+ GP
Sbjct: 683  LLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGA--------QGLPGP 734

Query: 1670 RGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQ 1729
            +G  G  G+KG +G PG+PG PG  G  G     G +G  G +G  GPPG +G  G  G 
Sbjct: 735  QGAIGPPGEKGPLGKPGLPGMPGADGPPGHP---GKEGPPGEKGGQGPPGPQGPIGYPGP 791

Query: 1730 PVYSQCDLIRFLR 1742
                  D IR L+
Sbjct: 792  RGVKGADGIRGLK 804



 Score =  191 bits (486), Expect = 6e-48
 Identities = 115/301 (38%), Positives = 139/301 (46%), Gaps = 35/301 (11%)

Query: 1454 KGFSGPKGGHGDDG----------IDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPG 1503
            +G  GP+G  G  G          I+G  G EG  G PG  G  G  G  G PG RG PG
Sbjct: 443  EGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPG 502

Query: 1504 QYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQG--------------RSGQKGVQGSPS 1549
            + G  G  G PG PG    +  + G  G+ G +G              +  +  ++G   
Sbjct: 503  RPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAG 562

Query: 1550 SRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQG 1609
              G  GR G  G  G  G  G PG  G  G  G+QGP G  G PGR+G  GS G +G  G
Sbjct: 563  PMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPG 622

Query: 1610 SPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGP 1669
              G  G +G  G  GL G+KG  G PG  GP G  G  G +GD            G  GP
Sbjct: 623  QTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDD-----------GEVGP 671

Query: 1670 RGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQ 1729
            RG PG+ G +G +G  G PG PGP G  G+    G KG  G +G PGPPGQ+G  G  G 
Sbjct: 672  RGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGL 731

Query: 1730 P 1730
            P
Sbjct: 732  P 732



 Score =  184 bits (466), Expect = 1e-45
 Identities = 120/324 (37%), Positives = 144/324 (44%), Gaps = 71/324 (21%)

Query: 1394 PGIPGPHGTRGLQAMKGSQG---------LKGSRGHRGEDGNPGVRGDTGPQGDKGIAGC 1444
            PG PGP G  G     G QG           G +G  GE G PG+ G+ GP G KG  G 
Sbjct: 1251 PGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGE 1310

Query: 1445 PGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQ 1504
             G  G  G  G  GPKG  GDDG  G  G  G  G PG  GE G  G  G PG +G  G+
Sbjct: 1311 KGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGE 1370

Query: 1505 YGEKGFPGDPGNPGQNN--------------NIKGQKGSKGEQGRQGRSGQ------KGV 1544
             G+ G PG  G PG +                 +G+KG+KGE G +G  G+      +G 
Sbjct: 1371 PGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGA 1430

Query: 1545 QGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGL------QGPQGSQGNPG---- 1594
             G P   G RG  G  G +G+ G PG  GP G +G  GL       GP+G +G+PG    
Sbjct: 1431 PGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGL 1490

Query: 1595 -----RKGEKGSQGQKGPQGS---------------------------PGLMGAKGSTGR 1622
                  +GEKG +G  GPQGS                           PG  GAKGS+G 
Sbjct: 1491 IGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGP 1550

Query: 1623 PGLLGKKGEPGLPGDLGPVGQTGQ 1646
             G  G+ G PG PG  GP G+  Q
Sbjct: 1551 TGPKGEAGHPGPPGPPGPPGEVIQ 1574



 Score =  167 bits (422), Expect = 2e-40
 Identities = 103/255 (40%), Positives = 115/255 (45%), Gaps = 17/255 (6%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PGP G  G    KGS G  G  G  G  G PG  G  GP GDKG  G PG  G  G  
Sbjct: 1321 GPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPT 1380

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGE---------------KGDPGSQGSPGSR 1499
            G  GP G  G  G  G  G EG  G  G KGE               +G PG  G  G R
Sbjct: 1381 GEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLR 1440

Query: 1500 GAPGQYGEKGFPGDPGNPGQNNNI--KGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGRE 1557
            G PG  GE+G PG PG  G    +   G  G KG+ G +G  G  G+ G     G +G +
Sbjct: 1441 GIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEK 1500

Query: 1558 GQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAK 1617
            G RGL G  G  G  G  G  G  G  GP G  G PG  G KG++G  GP G  G  G  
Sbjct: 1501 GDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHP 1560

Query: 1618 GSTGRPGLLGKKGEP 1632
            G  G PG  G+  +P
Sbjct: 1561 GPPGPPGPPGEVIQP 1575



 Score =  104 bits (259), Expect = 1e-21
 Identities = 69/202 (34%), Positives = 89/202 (44%), Gaps = 16/202 (7%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PGP G  G     G  GLKG  G +GE G+PG+ G  GP         PG  G+KG 
Sbjct: 1452 PGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGP---------PGEQGEKGD 1502

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD 1513
            +G  GP+G  G  G  G+ G  G  G PG  G  G PG +G+ GS G  G  GE G PG 
Sbjct: 1503 RGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGP 1562

Query: 1514 PGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPG 1573
            PG PG    +      +  + R+        Q      G    +   G+  + G   +  
Sbjct: 1563 PGPPGPPGEVIQPLPIQASRTRRNIDAS---QLLDDGNGENYVDYADGMEEIFGSLNSL- 1618

Query: 1574 PTGTLGAEGLQGPQGSQGNPGR 1595
                L  E ++ P G+Q NP R
Sbjct: 1619 ---KLEIEQMKRPLGTQQNPAR 1637



 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 33/84 (39%), Positives = 43/84 (51%), Gaps = 10/84 (11%)

Query: 1654 GIPGYGQMGRKGVKGPRGFPGDAGQKGD--IGNPGI-----PGGPGPKGFRGLALTVGLK 1706
            G+P       +G+ GPR   G+ GQKG+  I  PG+     PG  GP G  G   T+G  
Sbjct: 433  GMPANQDTIYEGIGGPR---GEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPT 489

Query: 1707 GEEGSRGLPGPPGQRGIKGMAGQP 1730
            G+ G  G  GPPG+ G+ G  G P
Sbjct: 490  GQVGDPGERGPPGRPGLPGADGLP 513


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score =  271 bits (692), Expect = 8e-72
 Identities = 158/366 (43%), Positives = 186/366 (50%), Gaps = 35/366 (9%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PG  G +G     G  G  G +G RG  G  G RG+ GP G +G  G  GA G+ G 
Sbjct: 715  PGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGA 774

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD 1513
            KG SG  G HG  G  GL G +G +GFPG KG  G PG  G PG    PGQ GE GF G 
Sbjct: 775  KGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGH---PGQRGEVGFQGK 831

Query: 1514 PGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSR---GSRGREGQRGLRGVSGEPG 1570
             G PG    + G +G+ GE G  G  G  G  G P  +   G+ G+EG +G  G  G PG
Sbjct: 832  TGPPGP-PGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG 890

Query: 1571 NPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGS------TGRPG 1624
              GP G  G  G +G  G+ G PG KG +G  G  GP GSPG  GA GS       GRPG
Sbjct: 891  KDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPG 950

Query: 1625 LL---GKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG-------------------YGQMG 1662
                 G  GE G+PG+ GP+G TG+ G QG  G+PG                    GQ G
Sbjct: 951  PQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKG 1010

Query: 1663 RKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRG 1722
             KG KG  G PG  G  G +G PG  G  G  G RG     G KG+EG+RG  GPPG  G
Sbjct: 1011 TKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIG 1070

Query: 1723 IKGMAG 1728
            ++G+ G
Sbjct: 1071 LQGLPG 1076



 Score =  263 bits (673), Expect = 1e-69
 Identities = 146/337 (43%), Positives = 187/337 (55%), Gaps = 11/337 (3%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PGP G +G+    G +GLKG +G +GEDG PG +GD G +GD+G  G PG+ G+ G +
Sbjct: 629  GYPGPRGVKGVD---GIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPE 685

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDP 1514
            G  G  G  GD G  GL GE+G  G PG+ G  G  G +GS G  G PG  GEKG  G  
Sbjct: 686  GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLS 745

Query: 1515 GNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGP 1574
            G  G     +G  G +G++G +G +G+ G +G+    G  G  G+RGL G  G  G PGP
Sbjct: 746  GKSGPRGE-RGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 804

Query: 1575 TGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGL 1634
             G  G  G     G  G+PG++GE G QG+ GP G PG++G +G+ G  G +G++G PG 
Sbjct: 805  KGPPGPPG---KDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGP 861

Query: 1635 PGDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGP 1693
            PG  G  G  G  G++G  G PG  G  G+ G  G RGFPG+ G  G  G PG+ G  GP
Sbjct: 862  PGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGP 921

Query: 1694 KGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
             G  G A   G  GE G+ G  GP G  G  G  G P
Sbjct: 922  SGPPGPA---GSPGERGAAGSGGPIGPPGRPGPQGPP 955



 Score =  259 bits (663), Expect = 2e-68
 Identities = 157/366 (42%), Positives = 184/366 (50%), Gaps = 37/366 (10%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRG---HRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQK 1451
            G  GPHG +G Q   G  G+ GS G   H G++G PG +G+ GP G +G  G PG  G K
Sbjct: 578  GAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVK 637

Query: 1452 GLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFP 1511
            G+ G  G KG  G+ G DG  G +G  G  G +GE G PGS+G  G  G  G+ G  G P
Sbjct: 638  GVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDP 697

Query: 1512 GDPGNPGQNNNI-----------KGQKGSKGEQGRQGRSGQKGVQG---SPSSRGSRGRE 1557
            G PG  G+   +           +G KGS G  G  G SG+KG +G       RG RG  
Sbjct: 698  GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 757

Query: 1558 GQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPG---LM 1614
            G RG RG  G  G  G  GT G +G  GP G +G PG +G  G  G KGP G PG   L 
Sbjct: 758  GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLP 817

Query: 1615 GAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPG 1674
            G  G  G  G  GK G PG PG +GP G  G+ G  G+ G PG       G  G +G PG
Sbjct: 818  GHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPG-----PPGPPGEQGLPG 872

Query: 1675 DAGQ---KGDIGNPGIPGGPGPKGFRGL---------ALTVGLKGEEGSRGLPGPPGQRG 1722
             AG+   KGD G PG PG  GP G RG          A   GLKG EG  G PGP G  G
Sbjct: 873  TAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG 932

Query: 1723 IKGMAG 1728
             +G AG
Sbjct: 933  ERGAAG 938



 Score =  259 bits (663), Expect = 2e-68
 Identities = 150/361 (41%), Positives = 180/361 (49%), Gaps = 30/361 (8%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PGP G +GL    G +G  G  G  G  G PG RG  GP G  G  G PG  G  G  
Sbjct: 1064 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPP 1123

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKG----- 1509
            G  G  G  G  GI G  G +G  G  G KGE G PG  G PG +G  G  G KG     
Sbjct: 1124 GEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPV 1183

Query: 1510 -FPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQ------------------KGVQGSPSS 1550
             FPGDPG PG+    +GQ G+KG++G  G  GQ                  +G  GSP S
Sbjct: 1184 GFPGDPGPPGEGGP-RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGS 1242

Query: 1551 RGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGS 1610
             G +G +G +G  G  G PG  GP G  G  G  GP G +G PG  G++G  G  G  G 
Sbjct: 1243 EGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGP 1302

Query: 1611 PGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPR 1670
            PG +G  G  G  G  G KGE G PG +G +G  G++G +GD G+PG    G  G KG  
Sbjct: 1303 PGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPG--PQGSPGQKGEM 1360

Query: 1671 GFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
            G PG +G  G  G PG+PG  GPKG +G     G  G +G +G+ GPPG  G  G   QP
Sbjct: 1361 GIPGASGPIGPGGPPGLPGPAGPKGAKG---ATGPGGPKGEKGVQGPPGHPGPPGEVIQP 1417

Query: 1731 V 1731
            +
Sbjct: 1418 L 1418



 Score =  259 bits (662), Expect = 2e-68
 Identities = 158/372 (42%), Positives = 184/372 (49%), Gaps = 41/372 (11%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG  GP G  G     G  G +G +GH G  G+ G RG  GP G  G+ G PG  G+KG 
Sbjct: 1024 PGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGE 1083

Query: 1454 KGF---------SGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAP-- 1502
             G           GP+G  G +G DG  G  G  G  G  GEKG+PG  GSPG +G P  
Sbjct: 1084 TGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGV 1143

Query: 1503 -------GQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRG 1555
                   G+ GE G PG+PG PG     KG  G  G +G  G  G  G  G P   G RG
Sbjct: 1144 KGPRGERGEKGESGQPGEPGPPGP----KGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRG 1199

Query: 1556 REGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMG 1615
            ++G +G RG  GEPG PG  G  G  G  GP G +G  G  G +G QG KG +G PG +G
Sbjct: 1200 QDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIG 1259

Query: 1616 AKGSTGRPGLLGKKGEP------GLPGDLGPVGQ---TGQRGRQGDSGIPGY----GQMG 1662
            A G TG  G  G  G+P      GLPG +G  G+   TGQ G  G  G PG     G  G
Sbjct: 1260 APGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAG 1319

Query: 1663 RKGVKGPRGF------PGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPG 1716
             KG KG  G       PG+ G+KGD G PG  G PG KG  G+    G  G  G  GLPG
Sbjct: 1320 AKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPG 1379

Query: 1717 PPGQRGIKGMAG 1728
            P G +G KG  G
Sbjct: 1380 PAGPKGAKGATG 1391



 Score =  258 bits (659), Expect = 5e-68
 Identities = 147/369 (39%), Positives = 194/369 (52%), Gaps = 38/369 (10%)

Query: 1394 PGIPGPHGT---------------------------------RGLQAMKGSQGLKGSRGH 1420
            PG+PG  G+                                 RG++ + G +GLKG +G 
Sbjct: 592  PGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGE 651

Query: 1421 RGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGF 1480
            +GEDG PG +GD G +GD+G  G PG+ G+ G +G  G  G  GD G  GL GE+G  G 
Sbjct: 652  KGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGV 711

Query: 1481 PGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSG 1540
            PG+ G  G  G +GS G  G PG  GEKG  G  G  G     +G  G +G++G +G +G
Sbjct: 712  PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGE-RGPTGPRGQRGPRGATG 770

Query: 1541 QKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKG 1600
            + G +G+    G  G  G+RGL G  G  G PGP    G  G  G  G  G+PG++GE G
Sbjct: 771  KSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK---GPPGPPGKDGLPGHPGQRGEVG 827

Query: 1601 SQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG-YG 1659
             QG+ GP G PG++G +G+ G  G +G++G PG PG  G  G  G  G++G  G PG  G
Sbjct: 828  FQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPG 887

Query: 1660 QMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPG 1719
              G+ G  G RGFPG+ G  G  G PG+ G  GP G  G A + G +G  GS G  GPPG
Sbjct: 888  APGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPG 947

Query: 1720 QRGIKGMAG 1728
            + G +G  G
Sbjct: 948  RPGPQGPPG 956



 Score =  255 bits (652), Expect = 3e-67
 Identities = 153/365 (41%), Positives = 177/365 (48%), Gaps = 33/365 (9%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G+PG  G RGL   KG  G+ G  G RG DG  G +G  GPQG+ G    PG  G  G +
Sbjct: 515  GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP---PGQQGTPGTQ 571

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDP 1514
            G  GP+G  G  G  G  G+ G  G PG  G  G PG +G PG++G  G  G +G  G P
Sbjct: 572  GLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYP 631

Query: 1515 GNPGQN--NNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNP 1572
            G  G    + I+G KG KGE+G  G  G KG  G    RG  G  G RG  G  G  G  
Sbjct: 632  GPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRT 691

Query: 1573 GPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEP 1632
            GPTG  G  GL G +G  G PG  G  G QG KG  G PG  GA G  G  GL GK G  
Sbjct: 692  GPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPR 751

Query: 1633 GLPGDLGPVGQTGQRGRQGDSGIPGY----------GQMGRKGVKGPRGFPGDAGQKGDI 1682
            G  G  GP GQ G RG  G SG  G           G+ G  G +GP GFPG  G  G  
Sbjct: 752  GERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPP 811

Query: 1683 GNPGIPGGPGPKGF------------------RGLALTVGLKGEEGSRGLPGPPGQRGIK 1724
            G  G+PG PG +G                   +G A   G  GE G  G PGPPG++G+ 
Sbjct: 812  GKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLP 871

Query: 1725 GMAGQ 1729
            G AG+
Sbjct: 872  GTAGK 876



 Score =  253 bits (647), Expect = 1e-66
 Identities = 150/355 (42%), Positives = 178/355 (50%), Gaps = 23/355 (6%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G+PG  G  GL+  +G  G  G  G  GE G  G  G  GP G  G  G PGA G+KG+ 
Sbjct: 905  GLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVP 964

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDP 1514
            G  GP G  G DG+ G  G  G  G PG+ GE GD G  G PG +G  G  GE G PG P
Sbjct: 965  GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPP 1024

Query: 1515 G---------------NPGQNNNIKGQKGSKGEQGRQGRSGQKG---VQGSPSSRGSRGR 1556
            G                PG     +G  G+KG++G +G +G  G   +QG P   G +G 
Sbjct: 1025 GPIGPVGQPGAAGADGEPGARGP-QGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGE 1083

Query: 1557 EGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGA 1616
             G  G  G  G PG  GP G  GA+G QGP G  GN G  GEKG  G+ G  G  G  G 
Sbjct: 1084 TGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGV 1143

Query: 1617 KGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGVKGPRGFPGD 1675
            KG  G  G  G+ G+PG PG  GP G TG  G +G+ G  G+ G  G  G  GPRG  G 
Sbjct: 1144 KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGA 1203

Query: 1676 AGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
             G +G+ G PG PG PGP G  G     G  G+ G  G PG  G++G KG  G P
Sbjct: 1204 KGDRGEDGEPGQPGSPGPTGENG---PPGPLGKRGPAGSPGSEGRQGGKGAKGDP 1255



 Score =  253 bits (647), Expect = 1e-66
 Identities = 154/370 (41%), Positives = 179/370 (48%), Gaps = 38/370 (10%)

Query: 1395 GIPGPHGTRGLQAMKGSQG------LKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAW 1448
            G+PGP G  G+    G +G       KG++G++GE G PG  G  GP G  G AG  G  
Sbjct: 983  GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEP 1042

Query: 1449 GQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKG---DPGSQGSPGSRGAPGQY 1505
            G +G +G  G KG  G  G +G  G  G  G PG  GEKG   D G  G PG  G  G  
Sbjct: 1043 GARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPA 1102

Query: 1506 GEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGV 1565
            G  G  G  G PG   N+    G  GE+G  G SG  G+QG P  +G RG  G++G  G 
Sbjct: 1103 GPNGADGPQGPPGGVGNL----GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQ 1158

Query: 1566 SGEPGNP---GPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGR 1622
             GEPG P   GPTG  G +G  GP G  G+PG  GE G +GQ G +G  G  G  G  G 
Sbjct: 1159 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGS 1218

Query: 1623 PGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG----------------YGQMGRKGV 1666
            PG  G+ G PG  G  GP G  G  GRQG  G  G                 G  G+ G 
Sbjct: 1219 PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGP 1278

Query: 1667 KGPRGFPGDAGQK------GDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQ 1720
             G RG PG  GQ+      G  G PG  G PG  G RG A   G KG  G  GL GPPG+
Sbjct: 1279 DGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGE 1338

Query: 1721 RGIKGMAGQP 1730
            +G KG  G P
Sbjct: 1339 QGEKGDRGLP 1348



 Score =  251 bits (641), Expect = 6e-66
 Identities = 140/329 (42%), Positives = 171/329 (51%), Gaps = 9/329 (2%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PGP G  G     G QG  G  G+ G  G  G  G++G  G +G  G  G  G++G 
Sbjct: 1093 PGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGE 1152

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD 1513
            KG SG  G  G  G  G  G++G  G PG  G  GDPG  G  G RG  G  G++G  G+
Sbjct: 1153 KGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGE 1212

Query: 1514 PGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPG 1573
            PG P       G  G  GE G  G  G++G  GSP S G +G +G +G  G  G PG  G
Sbjct: 1213 PGQP-------GSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1265

Query: 1574 PTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPG 1633
            P G  G  G  GP G +G PG  G++G  G  G  G PG +G  G  G  G  G KGE G
Sbjct: 1266 PVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKG 1325

Query: 1634 LPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGP 1693
             PG +G +G  G++G +GD G+P  G  G  G KG  G PG +G  G  G PG+PG  GP
Sbjct: 1326 HPGLIGLIGPPGEQGEKGDRGLP--GPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGP 1383

Query: 1694 KGFRGLALTVGLKGEEGSRGLPGPPGQRG 1722
            KG +G     G KGE+G +G PG PG  G
Sbjct: 1384 KGAKGATGPGGPKGEKGVQGPPGHPGPPG 1412



 Score =  244 bits (624), Expect = 6e-64
 Identities = 150/352 (42%), Positives = 180/352 (51%), Gaps = 41/352 (11%)

Query: 1398 GPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFS 1457
            GP G  G     G  G  GS G +GE G+ G +G  GPQG   + G PG  G++G  G  
Sbjct: 401  GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG---LTGPPGKAGRRGRAGAD 457

Query: 1458 GPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNP 1517
            G +G  GD G+ G  G +G  G PG KG +GD G+QG PG  G  G+ G+ G  G  G P
Sbjct: 458  GARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLP 517

Query: 1518 GQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGT 1577
            G++          G +G  G  G  G+ G P  RG  G +G +G  G  GEPG PG  GT
Sbjct: 518  GES----------GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT 567

Query: 1578 LGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGD 1637
             G +GL GPQG+ G           G+KGPQG PGL G  GS G PG  GK+G PG  G+
Sbjct: 568  PGTQGLPGPQGAIG---------PHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN 618

Query: 1638 LGPVGQTGQRGRQGDSGIPGY----GQMGRKGVKGPRGFP---GDAGQKGDIGNPGIPG- 1689
             GP G  G  G  G  G+ G     G  G KG KG  GFP   GD G KGD G  G+PG 
Sbjct: 619  QGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGS 678

Query: 1690 ----GP-------GPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
                GP       GP G  G    +G KG+ G  GLPG PG++G KG  G P
Sbjct: 679  RGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFP 730



 Score =  233 bits (593), Expect = 2e-60
 Identities = 152/378 (40%), Positives = 176/378 (46%), Gaps = 45/378 (11%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSR-------GHRGEDGNPGVRGDT------------- 1433
            PG  GP G  GL    G+ G  G+        G  G D  P V                 
Sbjct: 339  PGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLA 398

Query: 1434 --GPQGDKGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPG 1491
              GP G  G  G PG  GQ G  G    KG  GD G  G  G +G  G PG  G +G  G
Sbjct: 399  LRGPPGPMGYTGRPGPLGQPGSPGL---KGESGDLGPQGPRGPQGLTGPPGKAGRRGRAG 455

Query: 1492 SQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSR 1551
            + G+ G  G PG  G++GF G PG PG+  + +G  G++G  G  G  G++G  G    R
Sbjct: 456  ADGARGMPGDPGVKGDRGFDGLPGLPGEKGH-RGDTGAQGLPGPPGEDGERGDDGEIGPR 514

Query: 1552 GSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSP 1611
            G  G  G RGL G  G PG PGP G  G +G QGP+GS G  G  G  G QG  G QG P
Sbjct: 515  GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP 574

Query: 1612 GLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQ------RGRQGDSGIPG----YGQM 1661
            G  GA G  G  G  GK G PG+PG  GP G  G+      +G QG SG  G     G  
Sbjct: 575  GPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR 634

Query: 1662 GRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGL------- 1714
            G KGV G RG  G  G+KG+ G PG  G  G KG RG     G +GE+G  G        
Sbjct: 635  GVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPT 694

Query: 1715 --PGPPGQRGIKGMAGQP 1730
              PGPPG  G KG  G P
Sbjct: 695  GDPGPPGLMGEKGKLGVP 712



 Score =  207 bits (528), Expect = 8e-53
 Identities = 142/372 (38%), Positives = 173/372 (46%), Gaps = 40/372 (10%)

Query: 1400 HGTRGLQAMKGS----------QGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWG 1449
            HG RGL+  KG           +G  G  G  G  G PG++G+ GP GD G  G PG  G
Sbjct: 290  HGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAG 349

Query: 1450 QKGLKGFSGPKG-----------GHGDDGIDGLDGEEGCHGFP-----GIKGEKGDPGSQ 1493
              G  G  GP G           G GD G      E             ++G  G  G  
Sbjct: 350  LPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYT 409

Query: 1494 GSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGS 1553
            G PG  G PG  G KG  GD G  G     +G  G  G+ GR+GR+G  G +G P   G 
Sbjct: 410  GRPGPLGQPGSPGLKGESGDLGPQGPRGP-QGLTGPPGKAGRRGRAGADGARGMP---GD 465

Query: 1554 RGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGL 1613
             G +G RG  G+ G PG  G  G  GA+GL GP      PG  GE+G  G+ GP+G PG 
Sbjct: 466  PGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGP------PGEDGERGDDGEIGPRGLPGE 519

Query: 1614 MGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGVKGPRGF 1672
             G +G  G  G  G  G PG+ G  GP G  G  G QG+ G PG  G  G +G+ GP+G 
Sbjct: 520  SGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGA 579

Query: 1673 PGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVY 1732
             G  G+KG  G PG+PG PG  G  G     G +G  G++G  GP G +G  G  G    
Sbjct: 580  IGPHGEKGPQGKPGLPGMPGSDGPPGHP---GKEGPPGTKGNQGPSGPQGPLGYPGPRGV 636

Query: 1733 SQCDLIRFLREH 1744
               D IR L+ H
Sbjct: 637  KGVDGIRGLKGH 648



 Score =  190 bits (483), Expect = 1e-47
 Identities = 132/333 (39%), Positives = 153/333 (45%), Gaps = 48/333 (14%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PG  G  G++  +G +G KG  G  GE G PG +G TG  G KG  G  G  G  G  
Sbjct: 1133 GSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPP 1192

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGS------QGSPGSRGAPGQYGEK 1508
            G  GP+G  G  G  G DGE G  G PG  GE G PG        GSPGS G  G  G K
Sbjct: 1193 GEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAK 1252

Query: 1509 GFPGDPGNPGQN--------------NNIKGQKGSKGEQGRQGRSGQKGVQGS------P 1548
            G PG  G PG+               + ++G  GS G+QGR G +GQ G  G       P
Sbjct: 1253 GDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLP 1312

Query: 1549 SSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQ 1608
              RG  G +G++G  G+ G  G PG  G  G  GL GPQGS   PG+KGE G  G  GP 
Sbjct: 1313 GLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGS---PGQKGEMGIPGASGPI 1369

Query: 1609 GSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG---------YG 1659
            G PG     G  G PG  G KG  G  G  GP G+ G +G  G  G PG           
Sbjct: 1370 G-PG-----GPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMP 1423

Query: 1660 QMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPG 1692
            +  R+ V G R    D      I   G PG PG
Sbjct: 1424 KKTRRSVDGSRLMQEDEA----IPTGGAPGSPG 1452



 Score =  189 bits (479), Expect = 4e-47
 Identities = 126/330 (38%), Positives = 163/330 (49%), Gaps = 24/330 (7%)

Query: 1417 SRGHRGEDGNPGVRGDTGPQGDKGIAGC------PGAWGQKGLKGFSG-PKGGHGDDGID 1469
            SR HR ++  P  +  T  + ++ +           A G +GLKG  G P        ++
Sbjct: 253  SRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVE 312

Query: 1470 GLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGS 1529
            G  G EG  G  G  G +G+PG  G PG RG PG+ G  G  G PG PG +  +  + GS
Sbjct: 313  GPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGS 372

Query: 1530 KGEQGRQGRSGQKG------VQGSPSSRGSRGREGQRGLRGVSGEPGNP---GPTGTLGA 1580
             G       + Q+        Q   + RG  G  G  G  G  G+PG+P   G +G LG 
Sbjct: 373  GGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGP 432

Query: 1581 EGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGP 1640
            +G +GPQG  G PG+ G +G  G  G +G PG  G KG  G  GL      PGLPG+ G 
Sbjct: 433  QGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGL------PGLPGEKGH 486

Query: 1641 VGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLA 1700
             G TG +G  G  G    G+ G  G  GPRG PG++G +G +G  G PG PGP G RG+ 
Sbjct: 487  RGDTGAQGLPGPPGED--GERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMD 544

Query: 1701 LTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
               G KG  G +G PGPPGQ+G  G  G P
Sbjct: 545  GPQGPKGSLGPQGEPGPPGQQGTPGTQGLP 574



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 67/211 (31%), Positives = 96/211 (45%), Gaps = 30/211 (14%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG  G  G  G     G  GL+G  G +GE G+PG+ G  GP G++      G  G +GL
Sbjct: 1294 PGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQ------GEKGDRGL 1347

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD 1513
             G  G  G  G+ GI G  G  G  G PG+ G  G  G++G+ G  G  G+ G +G PG 
Sbjct: 1348 PGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGH 1407

Query: 1514 PGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPG 1573
            PG PG+   I+       ++ R+   G + +Q   +                 G PG+PG
Sbjct: 1408 PGPPGE--VIQPLPIQMPKKTRRSVDGSRLMQEDEAI-------------PTGGAPGSPG 1452

Query: 1574 PT----GTLGA-----EGLQGPQGSQGNPGR 1595
                  G+L +     E ++ P G+Q +P R
Sbjct: 1453 GLEEIFGSLDSLREEIEQMRRPTGTQDSPAR 1483


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score =  271 bits (692), Expect = 8e-72
 Identities = 158/366 (43%), Positives = 186/366 (50%), Gaps = 35/366 (9%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PG  G +G     G  G  G +G RG  G  G RG+ GP G +G  G  GA G+ G 
Sbjct: 694  PGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGA 753

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD 1513
            KG SG  G HG  G  GL G +G +GFPG KG  G PG  G PG    PGQ GE GF G 
Sbjct: 754  KGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGH---PGQRGEVGFQGK 810

Query: 1514 PGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSR---GSRGREGQRGLRGVSGEPG 1570
             G PG    + G +G+ GE G  G  G  G  G P  +   G+ G+EG +G  G  G PG
Sbjct: 811  TGPPGP-PGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG 869

Query: 1571 NPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGS------TGRPG 1624
              GP G  G  G +G  G+ G PG KG +G  G  GP GSPG  GA GS       GRPG
Sbjct: 870  KDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPG 929

Query: 1625 LL---GKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG-------------------YGQMG 1662
                 G  GE G+PG+ GP+G TG+ G QG  G+PG                    GQ G
Sbjct: 930  PQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKG 989

Query: 1663 RKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRG 1722
             KG KG  G PG  G  G +G PG  G  G  G RG     G KG+EG+RG  GPPG  G
Sbjct: 990  TKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIG 1049

Query: 1723 IKGMAG 1728
            ++G+ G
Sbjct: 1050 LQGLPG 1055



 Score =  263 bits (673), Expect = 1e-69
 Identities = 146/337 (43%), Positives = 187/337 (55%), Gaps = 11/337 (3%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PGP G +G+    G +GLKG +G +GEDG PG +GD G +GD+G  G PG+ G+ G +
Sbjct: 608  GYPGPRGVKGVD---GIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPE 664

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDP 1514
            G  G  G  GD G  GL GE+G  G PG+ G  G  G +GS G  G PG  GEKG  G  
Sbjct: 665  GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLS 724

Query: 1515 GNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGP 1574
            G  G     +G  G +G++G +G +G+ G +G+    G  G  G+RGL G  G  G PGP
Sbjct: 725  GKSGPRGE-RGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 783

Query: 1575 TGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGL 1634
             G  G  G     G  G+PG++GE G QG+ GP G PG++G +G+ G  G +G++G PG 
Sbjct: 784  KGPPGPPG---KDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGP 840

Query: 1635 PGDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGP 1693
            PG  G  G  G  G++G  G PG  G  G+ G  G RGFPG+ G  G  G PG+ G  GP
Sbjct: 841  PGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGP 900

Query: 1694 KGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
             G  G A   G  GE G+ G  GP G  G  G  G P
Sbjct: 901  SGPPGPA---GSPGERGAAGSGGPIGPPGRPGPQGPP 934



 Score =  259 bits (663), Expect = 2e-68
 Identities = 157/366 (42%), Positives = 184/366 (50%), Gaps = 37/366 (10%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRG---HRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQK 1451
            G  GPHG +G Q   G  G+ GS G   H G++G PG +G+ GP G +G  G PG  G K
Sbjct: 557  GAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVK 616

Query: 1452 GLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFP 1511
            G+ G  G KG  G+ G DG  G +G  G  G +GE G PGS+G  G  G  G+ G  G P
Sbjct: 617  GVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDP 676

Query: 1512 GDPGNPGQNNNI-----------KGQKGSKGEQGRQGRSGQKGVQG---SPSSRGSRGRE 1557
            G PG  G+   +           +G KGS G  G  G SG+KG +G       RG RG  
Sbjct: 677  GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 736

Query: 1558 GQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPG---LM 1614
            G RG RG  G  G  G  GT G +G  GP G +G PG +G  G  G KGP G PG   L 
Sbjct: 737  GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLP 796

Query: 1615 GAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPG 1674
            G  G  G  G  GK G PG PG +GP G  G+ G  G+ G PG       G  G +G PG
Sbjct: 797  GHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPG-----PPGPPGEQGLPG 851

Query: 1675 DAGQ---KGDIGNPGIPGGPGPKGFRGL---------ALTVGLKGEEGSRGLPGPPGQRG 1722
             AG+   KGD G PG PG  GP G RG          A   GLKG EG  G PGP G  G
Sbjct: 852  TAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG 911

Query: 1723 IKGMAG 1728
             +G AG
Sbjct: 912  ERGAAG 917



 Score =  259 bits (663), Expect = 2e-68
 Identities = 150/361 (41%), Positives = 180/361 (49%), Gaps = 30/361 (8%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PGP G +GL    G +G  G  G  G  G PG RG  GP G  G  G PG  G  G  
Sbjct: 1043 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPP 1102

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKG----- 1509
            G  G  G  G  GI G  G +G  G  G KGE G PG  G PG +G  G  G KG     
Sbjct: 1103 GEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPV 1162

Query: 1510 -FPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQ------------------KGVQGSPSS 1550
             FPGDPG PG+    +GQ G+KG++G  G  GQ                  +G  GSP S
Sbjct: 1163 GFPGDPGPPGEGGP-RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGS 1221

Query: 1551 RGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGS 1610
             G +G +G +G  G  G PG  GP G  G  G  GP G +G PG  G++G  G  G  G 
Sbjct: 1222 EGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGP 1281

Query: 1611 PGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPR 1670
            PG +G  G  G  G  G KGE G PG +G +G  G++G +GD G+PG    G  G KG  
Sbjct: 1282 PGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPG--PQGSPGQKGEM 1339

Query: 1671 GFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
            G PG +G  G  G PG+PG  GPKG +G     G  G +G +G+ GPPG  G  G   QP
Sbjct: 1340 GIPGASGPIGPGGPPGLPGPAGPKGAKG---ATGPGGPKGEKGVQGPPGHPGPPGEVIQP 1396

Query: 1731 V 1731
            +
Sbjct: 1397 L 1397



 Score =  259 bits (662), Expect = 2e-68
 Identities = 158/372 (42%), Positives = 184/372 (49%), Gaps = 41/372 (11%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG  GP G  G     G  G +G +GH G  G+ G RG  GP G  G+ G PG  G+KG 
Sbjct: 1003 PGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGE 1062

Query: 1454 KGF---------SGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAP-- 1502
             G           GP+G  G +G DG  G  G  G  G  GEKG+PG  GSPG +G P  
Sbjct: 1063 TGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGV 1122

Query: 1503 -------GQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRG 1555
                   G+ GE G PG+PG PG     KG  G  G +G  G  G  G  G P   G RG
Sbjct: 1123 KGPRGERGEKGESGQPGEPGPPGP----KGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRG 1178

Query: 1556 REGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMG 1615
            ++G +G RG  GEPG PG  G  G  G  GP G +G  G  G +G QG KG +G PG +G
Sbjct: 1179 QDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIG 1238

Query: 1616 AKGSTGRPGLLGKKGEP------GLPGDLGPVGQ---TGQRGRQGDSGIPGY----GQMG 1662
            A G TG  G  G  G+P      GLPG +G  G+   TGQ G  G  G PG     G  G
Sbjct: 1239 APGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAG 1298

Query: 1663 RKGVKGPRGF------PGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPG 1716
             KG KG  G       PG+ G+KGD G PG  G PG KG  G+    G  G  G  GLPG
Sbjct: 1299 AKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPG 1358

Query: 1717 PPGQRGIKGMAG 1728
            P G +G KG  G
Sbjct: 1359 PAGPKGAKGATG 1370



 Score =  258 bits (659), Expect = 5e-68
 Identities = 147/369 (39%), Positives = 194/369 (52%), Gaps = 38/369 (10%)

Query: 1394 PGIPGPHGT---------------------------------RGLQAMKGSQGLKGSRGH 1420
            PG+PG  G+                                 RG++ + G +GLKG +G 
Sbjct: 571  PGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGE 630

Query: 1421 RGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGF 1480
            +GEDG PG +GD G +GD+G  G PG+ G+ G +G  G  G  GD G  GL GE+G  G 
Sbjct: 631  KGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGV 690

Query: 1481 PGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSG 1540
            PG+ G  G  G +GS G  G PG  GEKG  G  G  G     +G  G +G++G +G +G
Sbjct: 691  PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGE-RGPTGPRGQRGPRGATG 749

Query: 1541 QKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKG 1600
            + G +G+    G  G  G+RGL G  G  G PGP    G  G  G  G  G+PG++GE G
Sbjct: 750  KSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK---GPPGPPGKDGLPGHPGQRGEVG 806

Query: 1601 SQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG-YG 1659
             QG+ GP G PG++G +G+ G  G +G++G PG PG  G  G  G  G++G  G PG  G
Sbjct: 807  FQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPG 866

Query: 1660 QMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPG 1719
              G+ G  G RGFPG+ G  G  G PG+ G  GP G  G A + G +G  GS G  GPPG
Sbjct: 867  APGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPG 926

Query: 1720 QRGIKGMAG 1728
            + G +G  G
Sbjct: 927  RPGPQGPPG 935



 Score =  255 bits (652), Expect = 3e-67
 Identities = 153/365 (41%), Positives = 177/365 (48%), Gaps = 33/365 (9%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G+PG  G RGL   KG  G+ G  G RG DG  G +G  GPQG+ G    PG  G  G +
Sbjct: 494  GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP---PGQQGTPGTQ 550

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDP 1514
            G  GP+G  G  G  G  G+ G  G PG  G  G PG +G PG++G  G  G +G  G P
Sbjct: 551  GLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYP 610

Query: 1515 GNPGQN--NNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNP 1572
            G  G    + I+G KG KGE+G  G  G KG  G    RG  G  G RG  G  G  G  
Sbjct: 611  GPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRT 670

Query: 1573 GPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEP 1632
            GPTG  G  GL G +G  G PG  G  G QG KG  G PG  GA G  G  GL GK G  
Sbjct: 671  GPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPR 730

Query: 1633 GLPGDLGPVGQTGQRGRQGDSGIPGY----------GQMGRKGVKGPRGFPGDAGQKGDI 1682
            G  G  GP GQ G RG  G SG  G           G+ G  G +GP GFPG  G  G  
Sbjct: 731  GERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPP 790

Query: 1683 GNPGIPGGPGPKGF------------------RGLALTVGLKGEEGSRGLPGPPGQRGIK 1724
            G  G+PG PG +G                   +G A   G  GE G  G PGPPG++G+ 
Sbjct: 791  GKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLP 850

Query: 1725 GMAGQ 1729
            G AG+
Sbjct: 851  GTAGK 855



 Score =  253 bits (647), Expect = 1e-66
 Identities = 150/355 (42%), Positives = 178/355 (50%), Gaps = 23/355 (6%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G+PG  G  GL+  +G  G  G  G  GE G  G  G  GP G  G  G PGA G+KG+ 
Sbjct: 884  GLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVP 943

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDP 1514
            G  GP G  G DG+ G  G  G  G PG+ GE GD G  G PG +G  G  GE G PG P
Sbjct: 944  GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPP 1003

Query: 1515 G---------------NPGQNNNIKGQKGSKGEQGRQGRSGQKG---VQGSPSSRGSRGR 1556
            G                PG     +G  G+KG++G +G +G  G   +QG P   G +G 
Sbjct: 1004 GPIGPVGQPGAAGADGEPGARGP-QGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGE 1062

Query: 1557 EGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGA 1616
             G  G  G  G PG  GP G  GA+G QGP G  GN G  GEKG  G+ G  G  G  G 
Sbjct: 1063 TGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGV 1122

Query: 1617 KGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGVKGPRGFPGD 1675
            KG  G  G  G+ G+PG PG  GP G TG  G +G+ G  G+ G  G  G  GPRG  G 
Sbjct: 1123 KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGA 1182

Query: 1676 AGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
             G +G+ G PG PG PGP G  G     G  G+ G  G PG  G++G KG  G P
Sbjct: 1183 KGDRGEDGEPGQPGSPGPTGENG---PPGPLGKRGPAGSPGSEGRQGGKGAKGDP 1234



 Score =  253 bits (647), Expect = 1e-66
 Identities = 154/370 (41%), Positives = 179/370 (48%), Gaps = 38/370 (10%)

Query: 1395 GIPGPHGTRGLQAMKGSQG------LKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAW 1448
            G+PGP G  G+    G +G       KG++G++GE G PG  G  GP G  G AG  G  
Sbjct: 962  GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEP 1021

Query: 1449 GQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKG---DPGSQGSPGSRGAPGQY 1505
            G +G +G  G KG  G  G +G  G  G  G PG  GEKG   D G  G PG  G  G  
Sbjct: 1022 GARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPA 1081

Query: 1506 GEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGV 1565
            G  G  G  G PG   N+    G  GE+G  G SG  G+QG P  +G RG  G++G  G 
Sbjct: 1082 GPNGADGPQGPPGGVGNL----GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQ 1137

Query: 1566 SGEPGNP---GPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGR 1622
             GEPG P   GPTG  G +G  GP G  G+PG  GE G +GQ G +G  G  G  G  G 
Sbjct: 1138 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGS 1197

Query: 1623 PGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG----------------YGQMGRKGV 1666
            PG  G+ G PG  G  GP G  G  GRQG  G  G                 G  G+ G 
Sbjct: 1198 PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGP 1257

Query: 1667 KGPRGFPGDAGQK------GDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQ 1720
             G RG PG  GQ+      G  G PG  G PG  G RG A   G KG  G  GL GPPG+
Sbjct: 1258 DGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGE 1317

Query: 1721 RGIKGMAGQP 1730
            +G KG  G P
Sbjct: 1318 QGEKGDRGLP 1327



 Score =  251 bits (641), Expect = 6e-66
 Identities = 140/329 (42%), Positives = 171/329 (51%), Gaps = 9/329 (2%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PGP G  G     G QG  G  G+ G  G  G  G++G  G +G  G  G  G++G 
Sbjct: 1072 PGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGE 1131

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD 1513
            KG SG  G  G  G  G  G++G  G PG  G  GDPG  G  G RG  G  G++G  G+
Sbjct: 1132 KGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGE 1191

Query: 1514 PGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPG 1573
            PG P       G  G  GE G  G  G++G  GSP S G +G +G +G  G  G PG  G
Sbjct: 1192 PGQP-------GSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1244

Query: 1574 PTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPG 1633
            P G  G  G  GP G +G PG  G++G  G  G  G PG +G  G  G  G  G KGE G
Sbjct: 1245 PVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKG 1304

Query: 1634 LPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGP 1693
             PG +G +G  G++G +GD G+P  G  G  G KG  G PG +G  G  G PG+PG  GP
Sbjct: 1305 HPGLIGLIGPPGEQGEKGDRGLP--GPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGP 1362

Query: 1694 KGFRGLALTVGLKGEEGSRGLPGPPGQRG 1722
            KG +G     G KGE+G +G PG PG  G
Sbjct: 1363 KGAKGATGPGGPKGEKGVQGPPGHPGPPG 1391



 Score =  244 bits (624), Expect = 6e-64
 Identities = 150/352 (42%), Positives = 180/352 (51%), Gaps = 41/352 (11%)

Query: 1398 GPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFS 1457
            GP G  G     G  G  GS G +GE G+ G +G  GPQG   + G PG  G++G  G  
Sbjct: 380  GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG---LTGPPGKAGRRGRAGAD 436

Query: 1458 GPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNP 1517
            G +G  GD G+ G  G +G  G PG KG +GD G+QG PG  G  G+ G+ G  G  G P
Sbjct: 437  GARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLP 496

Query: 1518 GQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGT 1577
            G++          G +G  G  G  G+ G P  RG  G +G +G  G  GEPG PG  GT
Sbjct: 497  GES----------GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT 546

Query: 1578 LGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGD 1637
             G +GL GPQG+ G           G+KGPQG PGL G  GS G PG  GK+G PG  G+
Sbjct: 547  PGTQGLPGPQGAIG---------PHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN 597

Query: 1638 LGPVGQTGQRGRQGDSGIPGY----GQMGRKGVKGPRGFP---GDAGQKGDIGNPGIPG- 1689
             GP G  G  G  G  G+ G     G  G KG KG  GFP   GD G KGD G  G+PG 
Sbjct: 598  QGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGS 657

Query: 1690 ----GP-------GPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
                GP       GP G  G    +G KG+ G  GLPG PG++G KG  G P
Sbjct: 658  RGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFP 709



 Score =  233 bits (593), Expect = 2e-60
 Identities = 152/378 (40%), Positives = 176/378 (46%), Gaps = 45/378 (11%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSR-------GHRGEDGNPGVRGDT------------- 1433
            PG  GP G  GL    G+ G  G+        G  G D  P V                 
Sbjct: 318  PGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLA 377

Query: 1434 --GPQGDKGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPG 1491
              GP G  G  G PG  GQ G  G    KG  GD G  G  G +G  G PG  G +G  G
Sbjct: 378  LRGPPGPMGYTGRPGPLGQPGSPGL---KGESGDLGPQGPRGPQGLTGPPGKAGRRGRAG 434

Query: 1492 SQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSR 1551
            + G+ G  G PG  G++GF G PG PG+  + +G  G++G  G  G  G++G  G    R
Sbjct: 435  ADGARGMPGDPGVKGDRGFDGLPGLPGEKGH-RGDTGAQGLPGPPGEDGERGDDGEIGPR 493

Query: 1552 GSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSP 1611
            G  G  G RGL G  G PG PGP G  G +G QGP+GS G  G  G  G QG  G QG P
Sbjct: 494  GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP 553

Query: 1612 GLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQ------RGRQGDSGIPG----YGQM 1661
            G  GA G  G  G  GK G PG+PG  GP G  G+      +G QG SG  G     G  
Sbjct: 554  GPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR 613

Query: 1662 GRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGL------- 1714
            G KGV G RG  G  G+KG+ G PG  G  G KG RG     G +GE+G  G        
Sbjct: 614  GVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPT 673

Query: 1715 --PGPPGQRGIKGMAGQP 1730
              PGPPG  G KG  G P
Sbjct: 674  GDPGPPGLMGEKGKLGVP 691



 Score =  208 bits (529), Expect = 6e-53
 Identities = 143/378 (37%), Positives = 174/378 (46%), Gaps = 40/378 (10%)

Query: 1394 PGIPGPHGTRGLQAMKGS----------QGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAG 1443
            P     HG RGL+  KG           +G  G  G  G  G PG++G+ GP GD G  G
Sbjct: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 322

Query: 1444 CPGAWGQKGLKGFSGPKG-----------GHGDDGIDGLDGEEGCHGFP-----GIKGEK 1487
             PG  G  G  G  GP G           G GD G      E             ++G  
Sbjct: 323  PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPP 382

Query: 1488 GDPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGS 1547
            G  G  G PG  G PG  G KG  GD G  G     +G  G  G+ GR+GR+G  G +G 
Sbjct: 383  GPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGP-QGLTGPPGKAGRRGRAGADGARGM 441

Query: 1548 PSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGP 1607
            P   G  G +G RG  G+ G PG  G  G  GA+GL GP      PG  GE+G  G+ GP
Sbjct: 442  P---GDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGP------PGEDGERGDDGEIGP 492

Query: 1608 QGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGV 1666
            +G PG  G +G  G  G  G  G PG+ G  GP G  G  G QG+ G PG  G  G +G+
Sbjct: 493  RGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGL 552

Query: 1667 KGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGM 1726
             GP+G  G  G+KG  G PG+PG PG  G  G     G +G  G++G  GP G +G  G 
Sbjct: 553  PGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP---GKEGPPGTKGNQGPSGPQGPLGY 609

Query: 1727 AGQPVYSQCDLIRFLREH 1744
             G       D IR L+ H
Sbjct: 610  PGPRGVKGVDGIRGLKGH 627



 Score =  191 bits (486), Expect = 6e-48
 Identities = 125/323 (38%), Positives = 158/323 (48%), Gaps = 31/323 (9%)

Query: 1417 SRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEG 1476
            SR HR ++  P  +   GP+G KG  G P       L              ++G  G EG
Sbjct: 253  SRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGML--------------VEGPPGPEG 298

Query: 1477 CHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQ 1536
              G  G  G +G+PG  G PG RG PG+ G  G  G PG PG +  +  + GS G     
Sbjct: 299  PAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGP 358

Query: 1537 GRSGQKG------VQGSPSSRGSRGREGQRGLRGVSGEPGNP---GPTGTLGAEGLQGPQ 1587
              + Q+        Q   + RG  G  G  G  G  G+PG+P   G +G LG +G +GPQ
Sbjct: 359  VVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQ 418

Query: 1588 GSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQR 1647
            G  G PG+ G +G  G  G +G PG  G KG  G  GL      PGLPG+ G  G TG +
Sbjct: 419  GLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGL------PGLPGEKGHRGDTGAQ 472

Query: 1648 GRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKG 1707
            G  G  G    G+ G  G  GPRG PG++G +G +G  G PG PGP G RG+    G KG
Sbjct: 473  GLPGPPGED--GERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKG 530

Query: 1708 EEGSRGLPGPPGQRGIKGMAGQP 1730
              G +G PGPPGQ+G  G  G P
Sbjct: 531  SLGPQGEPGPPGQQGTPGTQGLP 553



 Score =  190 bits (483), Expect = 1e-47
 Identities = 132/333 (39%), Positives = 153/333 (45%), Gaps = 48/333 (14%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PG  G  G++  +G +G KG  G  GE G PG +G TG  G KG  G  G  G  G  
Sbjct: 1112 GSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPP 1171

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGS------QGSPGSRGAPGQYGEK 1508
            G  GP+G  G  G  G DGE G  G PG  GE G PG        GSPGS G  G  G K
Sbjct: 1172 GEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAK 1231

Query: 1509 GFPGDPGNPGQN--------------NNIKGQKGSKGEQGRQGRSGQKGVQGS------P 1548
            G PG  G PG+               + ++G  GS G+QGR G +GQ G  G       P
Sbjct: 1232 GDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLP 1291

Query: 1549 SSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQ 1608
              RG  G +G++G  G+ G  G PG  G  G  GL GPQGS   PG+KGE G  G  GP 
Sbjct: 1292 GLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGS---PGQKGEMGIPGASGPI 1348

Query: 1609 GSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG---------YG 1659
            G PG     G  G PG  G KG  G  G  GP G+ G +G  G  G PG           
Sbjct: 1349 G-PG-----GPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMP 1402

Query: 1660 QMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPG 1692
            +  R+ V G R    D      I   G PG PG
Sbjct: 1403 KKTRRSVDGSRLMQEDEA----IPTGGAPGSPG 1431



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 67/211 (31%), Positives = 96/211 (45%), Gaps = 30/211 (14%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG  G  G  G     G  GL+G  G +GE G+PG+ G  GP G++      G  G +GL
Sbjct: 1273 PGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQ------GEKGDRGL 1326

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD 1513
             G  G  G  G+ GI G  G  G  G PG+ G  G  G++G+ G  G  G+ G +G PG 
Sbjct: 1327 PGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGH 1386

Query: 1514 PGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPG 1573
            PG PG+   I+       ++ R+   G + +Q   +                 G PG+PG
Sbjct: 1387 PGPPGE--VIQPLPIQMPKKTRRSVDGSRLMQEDEAI-------------PTGGAPGSPG 1431

Query: 1574 PT----GTLGA-----EGLQGPQGSQGNPGR 1595
                  G+L +     E ++ P G+Q +P R
Sbjct: 1432 GLEEIFGSLDSLREEIEQMRRPTGTQDSPAR 1462


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score =  271 bits (692), Expect = 8e-72
 Identities = 158/366 (43%), Positives = 186/366 (50%), Gaps = 35/366 (9%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PG  G +G     G  G  G +G RG  G  G RG+ GP G +G  G  GA G+ G 
Sbjct: 801  PGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGA 860

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD 1513
            KG SG  G HG  G  GL G +G +GFPG KG  G PG  G PG    PGQ GE GF G 
Sbjct: 861  KGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGH---PGQRGEVGFQGK 917

Query: 1514 PGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSR---GSRGREGQRGLRGVSGEPG 1570
             G PG    + G +G+ GE G  G  G  G  G P  +   G+ G+EG +G  G  G PG
Sbjct: 918  TGPPGP-PGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG 976

Query: 1571 NPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGS------TGRPG 1624
              GP G  G  G +G  G+ G PG KG +G  G  GP GSPG  GA GS       GRPG
Sbjct: 977  KDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPG 1036

Query: 1625 LL---GKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG-------------------YGQMG 1662
                 G  GE G+PG+ GP+G TG+ G QG  G+PG                    GQ G
Sbjct: 1037 PQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKG 1096

Query: 1663 RKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRG 1722
             KG KG  G PG  G  G +G PG  G  G  G RG     G KG+EG+RG  GPPG  G
Sbjct: 1097 TKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIG 1156

Query: 1723 IKGMAG 1728
            ++G+ G
Sbjct: 1157 LQGLPG 1162



 Score =  263 bits (673), Expect = 1e-69
 Identities = 146/337 (43%), Positives = 187/337 (55%), Gaps = 11/337 (3%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PGP G +G+    G +GLKG +G +GEDG PG +GD G +GD+G  G PG+ G+ G +
Sbjct: 715  GYPGPRGVKGVD---GIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPE 771

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDP 1514
            G  G  G  GD G  GL GE+G  G PG+ G  G  G +GS G  G PG  GEKG  G  
Sbjct: 772  GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLS 831

Query: 1515 GNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGP 1574
            G  G     +G  G +G++G +G +G+ G +G+    G  G  G+RGL G  G  G PGP
Sbjct: 832  GKSGPRGE-RGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 890

Query: 1575 TGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGL 1634
             G  G  G     G  G+PG++GE G QG+ GP G PG++G +G+ G  G +G++G PG 
Sbjct: 891  KGPPGPPG---KDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGP 947

Query: 1635 PGDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGP 1693
            PG  G  G  G  G++G  G PG  G  G+ G  G RGFPG+ G  G  G PG+ G  GP
Sbjct: 948  PGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGP 1007

Query: 1694 KGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
             G  G A   G  GE G+ G  GP G  G  G  G P
Sbjct: 1008 SGPPGPA---GSPGERGAAGSGGPIGPPGRPGPQGPP 1041



 Score =  259 bits (663), Expect = 2e-68
 Identities = 157/366 (42%), Positives = 184/366 (50%), Gaps = 37/366 (10%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRG---HRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQK 1451
            G  GPHG +G Q   G  G+ GS G   H G++G PG +G+ GP G +G  G PG  G K
Sbjct: 664  GAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVK 723

Query: 1452 GLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFP 1511
            G+ G  G KG  G+ G DG  G +G  G  G +GE G PGS+G  G  G  G+ G  G P
Sbjct: 724  GVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDP 783

Query: 1512 GDPGNPGQNNNI-----------KGQKGSKGEQGRQGRSGQKGVQG---SPSSRGSRGRE 1557
            G PG  G+   +           +G KGS G  G  G SG+KG +G       RG RG  
Sbjct: 784  GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 843

Query: 1558 GQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPG---LM 1614
            G RG RG  G  G  G  GT G +G  GP G +G PG +G  G  G KGP G PG   L 
Sbjct: 844  GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLP 903

Query: 1615 GAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPG 1674
            G  G  G  G  GK G PG PG +GP G  G+ G  G+ G PG       G  G +G PG
Sbjct: 904  GHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPG-----PPGPPGEQGLPG 958

Query: 1675 DAGQ---KGDIGNPGIPGGPGPKGFRGL---------ALTVGLKGEEGSRGLPGPPGQRG 1722
             AG+   KGD G PG PG  GP G RG          A   GLKG EG  G PGP G  G
Sbjct: 959  TAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG 1018

Query: 1723 IKGMAG 1728
             +G AG
Sbjct: 1019 ERGAAG 1024



 Score =  259 bits (663), Expect = 2e-68
 Identities = 149/352 (42%), Positives = 177/352 (50%), Gaps = 27/352 (7%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PGP G +GL    G +G  G  G  G  G PG RG  GP G  G  G PG  G  G  
Sbjct: 1150 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPP 1209

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKG----- 1509
            G  G  G  G  GI G  G +G  G  G KGE G PG  G PG +G  G  G KG     
Sbjct: 1210 GEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPV 1269

Query: 1510 -FPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQ------------------KGVQGSPSS 1550
             FPGDPG PG+    +GQ G+KG++G  G  GQ                  +G  GSP S
Sbjct: 1270 GFPGDPGPPGEGGP-RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGS 1328

Query: 1551 RGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGS 1610
             G +G +G +G  G  G PG  GP G  G  G  GP G +G PG  G++G  G  G  G 
Sbjct: 1329 EGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGP 1388

Query: 1611 PGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPR 1670
            PG +G  G  G  G  G KGE G PG +G +G  G++G +GD G+P  G  G  G KG  
Sbjct: 1389 PGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLP--GPQGSPGQKGEM 1446

Query: 1671 GFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRG 1722
            G PG +G  G  G PG+PG  GPKG +G     G KGE+G +G PG PG  G
Sbjct: 1447 GIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1498



 Score =  259 bits (662), Expect = 2e-68
 Identities = 158/372 (42%), Positives = 184/372 (49%), Gaps = 41/372 (11%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG  GP G  G     G  G +G +GH G  G+ G RG  GP G  G+ G PG  G+KG 
Sbjct: 1110 PGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGE 1169

Query: 1454 KGF---------SGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAP-- 1502
             G           GP+G  G +G DG  G  G  G  G  GEKG+PG  GSPG +G P  
Sbjct: 1170 TGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGV 1229

Query: 1503 -------GQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRG 1555
                   G+ GE G PG+PG PG     KG  G  G +G  G  G  G  G P   G RG
Sbjct: 1230 KGPRGERGEKGESGQPGEPGPPGP----KGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRG 1285

Query: 1556 REGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMG 1615
            ++G +G RG  GEPG PG  G  G  G  GP G +G  G  G +G QG KG +G PG +G
Sbjct: 1286 QDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIG 1345

Query: 1616 AKGSTGRPGLLGKKGEP------GLPGDLGPVGQ---TGQRGRQGDSGIPGY----GQMG 1662
            A G TG  G  G  G+P      GLPG +G  G+   TGQ G  G  G PG     G  G
Sbjct: 1346 APGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAG 1405

Query: 1663 RKGVKGPRGF------PGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPG 1716
             KG KG  G       PG+ G+KGD G PG  G PG KG  G+    G  G  G  GLPG
Sbjct: 1406 AKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPG 1465

Query: 1717 PPGQRGIKGMAG 1728
            P G +G KG  G
Sbjct: 1466 PAGPKGAKGATG 1477



 Score =  258 bits (659), Expect = 5e-68
 Identities = 147/369 (39%), Positives = 194/369 (52%), Gaps = 38/369 (10%)

Query: 1394 PGIPGPHGT---------------------------------RGLQAMKGSQGLKGSRGH 1420
            PG+PG  G+                                 RG++ + G +GLKG +G 
Sbjct: 678  PGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGE 737

Query: 1421 RGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGF 1480
            +GEDG PG +GD G +GD+G  G PG+ G+ G +G  G  G  GD G  GL GE+G  G 
Sbjct: 738  KGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGV 797

Query: 1481 PGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSG 1540
            PG+ G  G  G +GS G  G PG  GEKG  G  G  G     +G  G +G++G +G +G
Sbjct: 798  PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGE-RGPTGPRGQRGPRGATG 856

Query: 1541 QKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKG 1600
            + G +G+    G  G  G+RGL G  G  G PGP    G  G  G  G  G+PG++GE G
Sbjct: 857  KSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK---GPPGPPGKDGLPGHPGQRGEVG 913

Query: 1601 SQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG-YG 1659
             QG+ GP G PG++G +G+ G  G +G++G PG PG  G  G  G  G++G  G PG  G
Sbjct: 914  FQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPG 973

Query: 1660 QMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPG 1719
              G+ G  G RGFPG+ G  G  G PG+ G  GP G  G A + G +G  GS G  GPPG
Sbjct: 974  APGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPG 1033

Query: 1720 QRGIKGMAG 1728
            + G +G  G
Sbjct: 1034 RPGPQGPPG 1042



 Score =  255 bits (652), Expect = 3e-67
 Identities = 153/365 (41%), Positives = 177/365 (48%), Gaps = 33/365 (9%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G+PG  G RGL   KG  G+ G  G RG DG  G +G  GPQG+ G    PG  G  G +
Sbjct: 601  GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP---PGQQGTPGTQ 657

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDP 1514
            G  GP+G  G  G  G  G+ G  G PG  G  G PG +G PG++G  G  G +G  G P
Sbjct: 658  GLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYP 717

Query: 1515 GNPGQN--NNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNP 1572
            G  G    + I+G KG KGE+G  G  G KG  G    RG  G  G RG  G  G  G  
Sbjct: 718  GPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRT 777

Query: 1573 GPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEP 1632
            GPTG  G  GL G +G  G PG  G  G QG KG  G PG  GA G  G  GL GK G  
Sbjct: 778  GPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPR 837

Query: 1633 GLPGDLGPVGQTGQRGRQGDSGIPGY----------GQMGRKGVKGPRGFPGDAGQKGDI 1682
            G  G  GP GQ G RG  G SG  G           G+ G  G +GP GFPG  G  G  
Sbjct: 838  GERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPP 897

Query: 1683 GNPGIPGGPGPKGF------------------RGLALTVGLKGEEGSRGLPGPPGQRGIK 1724
            G  G+PG PG +G                   +G A   G  GE G  G PGPPG++G+ 
Sbjct: 898  GKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLP 957

Query: 1725 GMAGQ 1729
            G AG+
Sbjct: 958  GTAGK 962



 Score =  253 bits (647), Expect = 1e-66
 Identities = 150/355 (42%), Positives = 178/355 (50%), Gaps = 23/355 (6%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G+PG  G  GL+  +G  G  G  G  GE G  G  G  GP G  G  G PGA G+KG+ 
Sbjct: 991  GLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVP 1050

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDP 1514
            G  GP G  G DG+ G  G  G  G PG+ GE GD G  G PG +G  G  GE G PG P
Sbjct: 1051 GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPP 1110

Query: 1515 G---------------NPGQNNNIKGQKGSKGEQGRQGRSGQKG---VQGSPSSRGSRGR 1556
            G                PG     +G  G+KG++G +G +G  G   +QG P   G +G 
Sbjct: 1111 GPIGPVGQPGAAGADGEPGARGP-QGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGE 1169

Query: 1557 EGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGA 1616
             G  G  G  G PG  GP G  GA+G QGP G  GN G  GEKG  G+ G  G  G  G 
Sbjct: 1170 TGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGV 1229

Query: 1617 KGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGVKGPRGFPGD 1675
            KG  G  G  G+ G+PG PG  GP G TG  G +G+ G  G+ G  G  G  GPRG  G 
Sbjct: 1230 KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGA 1289

Query: 1676 AGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
             G +G+ G PG PG PGP G  G     G  G+ G  G PG  G++G KG  G P
Sbjct: 1290 KGDRGEDGEPGQPGSPGPTGENG---PPGPLGKRGPAGSPGSEGRQGGKGAKGDP 1341



 Score =  253 bits (647), Expect = 1e-66
 Identities = 154/370 (41%), Positives = 179/370 (48%), Gaps = 38/370 (10%)

Query: 1395 GIPGPHGTRGLQAMKGSQG------LKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAW 1448
            G+PGP G  G+    G +G       KG++G++GE G PG  G  GP G  G AG  G  
Sbjct: 1069 GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEP 1128

Query: 1449 GQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKG---DPGSQGSPGSRGAPGQY 1505
            G +G +G  G KG  G  G +G  G  G  G PG  GEKG   D G  G PG  G  G  
Sbjct: 1129 GARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPA 1188

Query: 1506 GEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGV 1565
            G  G  G  G PG   N+    G  GE+G  G SG  G+QG P  +G RG  G++G  G 
Sbjct: 1189 GPNGADGPQGPPGGVGNL----GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQ 1244

Query: 1566 SGEPGNP---GPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGR 1622
             GEPG P   GPTG  G +G  GP G  G+PG  GE G +GQ G +G  G  G  G  G 
Sbjct: 1245 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGS 1304

Query: 1623 PGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG----------------YGQMGRKGV 1666
            PG  G+ G PG  G  GP G  G  GRQG  G  G                 G  G+ G 
Sbjct: 1305 PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGP 1364

Query: 1667 KGPRGFPGDAGQK------GDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQ 1720
             G RG PG  GQ+      G  G PG  G PG  G RG A   G KG  G  GL GPPG+
Sbjct: 1365 DGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGE 1424

Query: 1721 RGIKGMAGQP 1730
            +G KG  G P
Sbjct: 1425 QGEKGDRGLP 1434



 Score =  244 bits (624), Expect = 6e-64
 Identities = 150/352 (42%), Positives = 180/352 (51%), Gaps = 41/352 (11%)

Query: 1398 GPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFS 1457
            GP G  G     G  G  GS G +GE G+ G +G  GPQG   + G PG  G++G  G  
Sbjct: 487  GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG---LTGPPGKAGRRGRAGAD 543

Query: 1458 GPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNP 1517
            G +G  GD G+ G  G +G  G PG KG +GD G+QG PG  G  G+ G+ G  G  G P
Sbjct: 544  GARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLP 603

Query: 1518 GQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGT 1577
            G++          G +G  G  G  G+ G P  RG  G +G +G  G  GEPG PG  GT
Sbjct: 604  GES----------GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT 653

Query: 1578 LGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGD 1637
             G +GL GPQG+ G           G+KGPQG PGL G  GS G PG  GK+G PG  G+
Sbjct: 654  PGTQGLPGPQGAIG---------PHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN 704

Query: 1638 LGPVGQTGQRGRQGDSGIPGY----GQMGRKGVKGPRGFP---GDAGQKGDIGNPGIPG- 1689
             GP G  G  G  G  G+ G     G  G KG KG  GFP   GD G KGD G  G+PG 
Sbjct: 705  QGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGS 764

Query: 1690 ----GP-------GPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
                GP       GP G  G    +G KG+ G  GLPG PG++G KG  G P
Sbjct: 765  RGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFP 816



 Score =  233 bits (593), Expect = 2e-60
 Identities = 152/378 (40%), Positives = 176/378 (46%), Gaps = 45/378 (11%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSR-------GHRGEDGNPGVRGDT------------- 1433
            PG  GP G  GL    G+ G  G+        G  G D  P V                 
Sbjct: 425  PGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLA 484

Query: 1434 --GPQGDKGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPG 1491
              GP G  G  G PG  GQ G  G    KG  GD G  G  G +G  G PG  G +G  G
Sbjct: 485  LRGPPGPMGYTGRPGPLGQPGSPGL---KGESGDLGPQGPRGPQGLTGPPGKAGRRGRAG 541

Query: 1492 SQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSR 1551
            + G+ G  G PG  G++GF G PG PG+  + +G  G++G  G  G  G++G  G    R
Sbjct: 542  ADGARGMPGDPGVKGDRGFDGLPGLPGEKGH-RGDTGAQGLPGPPGEDGERGDDGEIGPR 600

Query: 1552 GSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSP 1611
            G  G  G RGL G  G PG PGP G  G +G QGP+GS G  G  G  G QG  G QG P
Sbjct: 601  GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP 660

Query: 1612 GLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQ------RGRQGDSGIPG----YGQM 1661
            G  GA G  G  G  GK G PG+PG  GP G  G+      +G QG SG  G     G  
Sbjct: 661  GPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR 720

Query: 1662 GRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGL------- 1714
            G KGV G RG  G  G+KG+ G PG  G  G KG RG     G +GE+G  G        
Sbjct: 721  GVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPT 780

Query: 1715 --PGPPGQRGIKGMAGQP 1730
              PGPPG  G KG  G P
Sbjct: 781  GDPGPPGLMGEKGKLGVP 798



 Score =  207 bits (528), Expect = 8e-53
 Identities = 142/372 (38%), Positives = 173/372 (46%), Gaps = 40/372 (10%)

Query: 1400 HGTRGLQAMKGS----------QGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWG 1449
            HG RGL+  KG           +G  G  G  G  G PG++G+ GP GD G  G PG  G
Sbjct: 376  HGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAG 435

Query: 1450 QKGLKGFSGPKG-----------GHGDDGIDGLDGEEGCHGFP-----GIKGEKGDPGSQ 1493
              G  G  GP G           G GD G      E             ++G  G  G  
Sbjct: 436  LPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYT 495

Query: 1494 GSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGS 1553
            G PG  G PG  G KG  GD G  G     +G  G  G+ GR+GR+G  G +G P   G 
Sbjct: 496  GRPGPLGQPGSPGLKGESGDLGPQGPRGP-QGLTGPPGKAGRRGRAGADGARGMP---GD 551

Query: 1554 RGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGL 1613
             G +G RG  G+ G PG  G  G  GA+GL GP      PG  GE+G  G+ GP+G PG 
Sbjct: 552  PGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGP------PGEDGERGDDGEIGPRGLPGE 605

Query: 1614 MGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGVKGPRGF 1672
             G +G  G  G  G  G PG+ G  GP G  G  G QG+ G PG  G  G +G+ GP+G 
Sbjct: 606  SGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGA 665

Query: 1673 PGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVY 1732
             G  G+KG  G PG+PG PG  G  G     G +G  G++G  GP G +G  G  G    
Sbjct: 666  IGPHGEKGPQGKPGLPGMPGSDGPPGHP---GKEGPPGTKGNQGPSGPQGPLGYPGPRGV 722

Query: 1733 SQCDLIRFLREH 1744
               D IR L+ H
Sbjct: 723  KGVDGIRGLKGH 734



 Score =  190 bits (483), Expect = 1e-47
 Identities = 132/333 (39%), Positives = 153/333 (45%), Gaps = 48/333 (14%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PG  G  G++  +G +G KG  G  GE G PG +G TG  G KG  G  G  G  G  
Sbjct: 1219 GSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPP 1278

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGS------QGSPGSRGAPGQYGEK 1508
            G  GP+G  G  G  G DGE G  G PG  GE G PG        GSPGS G  G  G K
Sbjct: 1279 GEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAK 1338

Query: 1509 GFPGDPGNPGQN--------------NNIKGQKGSKGEQGRQGRSGQKGVQGS------P 1548
            G PG  G PG+               + ++G  GS G+QGR G +GQ G  G       P
Sbjct: 1339 GDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLP 1398

Query: 1549 SSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQ 1608
              RG  G +G++G  G+ G  G PG  G  G  GL GPQGS   PG+KGE G  G  GP 
Sbjct: 1399 GLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGS---PGQKGEMGIPGASGPI 1455

Query: 1609 GSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG---------YG 1659
            G PG     G  G PG  G KG  G  G  GP G+ G +G  G  G PG           
Sbjct: 1456 G-PG-----GPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMP 1509

Query: 1660 QMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPG 1692
            +  R+ V G R    D      I   G PG PG
Sbjct: 1510 KKTRRSVDGSRLMQEDEA----IPTGGAPGSPG 1538



 Score =  188 bits (478), Expect = 5e-47
 Identities = 120/294 (40%), Positives = 150/294 (51%), Gaps = 18/294 (6%)

Query: 1447 AWGQKGLKGFSG-PKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQY 1505
            A G +GLKG  G P        ++G  G EG  G  G  G +G+PG  G PG RG PG+ 
Sbjct: 375  AHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA 434

Query: 1506 GEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKG------VQGSPSSRGSRGREGQ 1559
            G  G  G PG PG +  +  + GS G       + Q+        Q   + RG  G  G 
Sbjct: 435  GLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGY 494

Query: 1560 RGLRGVSGEPGNP---GPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGA 1616
             G  G  G+PG+P   G +G LG +G +GPQG  G PG+ G +G  G  G +G PG  G 
Sbjct: 495  TGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGV 554

Query: 1617 KGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDA 1676
            KG  G  GL      PGLPG+ G  G TG +G  G  G    G+ G  G  GPRG PG++
Sbjct: 555  KGDRGFDGL------PGLPGEKGHRGDTGAQGLPGPPGED--GERGDDGEIGPRGLPGES 606

Query: 1677 GQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
            G +G +G  G PG PGP G RG+    G KG  G +G PGPPGQ+G  G  G P
Sbjct: 607  GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP 660



 Score = 92.8 bits (229), Expect = 4e-18
 Identities = 76/233 (32%), Positives = 93/233 (39%), Gaps = 81/233 (34%)

Query: 1578 LGAEGLQGPQGSQGNPGRKGEKGS----------QGQKGPQGSPGLMGAKGSTGRPGLLG 1627
            L AE       + G  G KGEKG           +G  GP+G  GL+G  G  G PG +G
Sbjct: 364  LSAETAHSGAAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVG 423

Query: 1628 KKGEPGLP-----------------------------GDLGPV----------------- 1641
              GE G P                             GD GPV                 
Sbjct: 424  DPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARL 483

Query: 1642 ---------GQTGQRGRQGDSGIPGY----GQMGRKGVKGPRGF---PGDAGQKGDIGNP 1685
                     G TG+ G  G  G PG     G +G +G +GP+G    PG AG++G  G  
Sbjct: 484  ALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGAD 543

Query: 1686 ---GIPGGPGPKGFRGLALTVGLKGEEGSR------GLPGPPGQRGIKGMAGQ 1729
               G+PG PG KG RG     GL GE+G R      GLPGPPG+ G +G  G+
Sbjct: 544  GARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGE 596



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 67/211 (31%), Positives = 96/211 (45%), Gaps = 30/211 (14%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG  G  G  G     G  GL+G  G +GE G+PG+ G  GP G++      G  G +GL
Sbjct: 1380 PGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQ------GEKGDRGL 1433

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD 1513
             G  G  G  G+ GI G  G  G  G PG+ G  G  G++G+ G  G  G+ G +G PG 
Sbjct: 1434 PGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGH 1493

Query: 1514 PGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPG 1573
            PG PG+   I+       ++ R+   G + +Q   +                 G PG+PG
Sbjct: 1494 PGPPGE--VIQPLPIQMPKKTRRSVDGSRLMQEDEAI-------------PTGGAPGSPG 1538

Query: 1574 PT----GTLGA-----EGLQGPQGSQGNPGR 1595
                  G+L +     E ++ P G+Q +P R
Sbjct: 1539 GLEEIFGSLDSLREEIEQMRRPTGTQDSPAR 1569


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score =  269 bits (688), Expect = 2e-71
 Identities = 154/346 (44%), Positives = 175/346 (50%), Gaps = 15/346 (4%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PG  G  G Q + G  G  G  G RGE G PG RG  G QG +G  G PG  G  G 
Sbjct: 671  PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGP 730

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD 1513
            KG SGP G  G  G  GL G  G  G  GI G KGD G  G  G  GAPG+ G +G  G 
Sbjct: 731  KGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGP 790

Query: 1514 PGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRG--------- 1564
             G PG      G  G KGE G  G +G  G +G+P  RG  G  G  G  G         
Sbjct: 791  IGPPGP----AGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPG 846

Query: 1565 VSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPG 1624
              GE G  G  G  GA G QGP G+ G  G  G  G +G +G QG PG  G  G+ GR G
Sbjct: 847  AKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVG 906

Query: 1625 LLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGN 1684
              G  G PG PG  GP G+ G +G +GDSG P  G+ G  G++GP G PG+ G+ GD G 
Sbjct: 907  PPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP--GRAGEPGLQGPAGPPGEKGEPGDDGP 964

Query: 1685 PGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
             G  G PGP+G  G    VGL G+ G RG PG PG  G  G  G P
Sbjct: 965  SGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAP 1010



 Score =  258 bits (660), Expect = 4e-68
 Identities = 150/371 (40%), Positives = 184/371 (49%), Gaps = 39/371 (10%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG+ GP G RG     G  G  G  G  G+ G  G RG  GPQG +G  G PG  G KG 
Sbjct: 233  PGVSGPMGPRG---PPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGH 289

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGC---HGFPGIKGEKGDPGSQG---------------S 1495
            +G+ G  G  G+ G  G+ GE G    +G PG  G +G PG +G                
Sbjct: 290  RGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQ 349

Query: 1496 PGSRGAPGQYGEKGFPGDPGNPGQNNNI--------KGQKGSKGEQGRQGRSGQKGVQGS 1547
            PG  G PG  G  G PG PG PG             +G +G +GE G  G  G  G  G+
Sbjct: 350  PGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGN 409

Query: 1548 PSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGP 1607
            P + G  G +G  G  G++G PG PGP G  G +G  GP G +G  G  G  G +G++GP
Sbjct: 410  PGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGP 469

Query: 1608 QGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGV 1666
            +G PG  G +G+ G  G  GK+G  G PG +GP+G  G+RG  G+ G PG  G  G KG 
Sbjct: 470  KGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGA 529

Query: 1667 KGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLA---------LTVGLKGEEGSRGLPGP 1717
             G RG  G AG KG  G+PG PG PG  G RGL            VG  G  G  G PGP
Sbjct: 530  PGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP 589

Query: 1718 PGQRGIKGMAG 1728
            PG +G +G  G
Sbjct: 590  PGPQGARGQPG 600



 Score =  258 bits (658), Expect = 7e-68
 Identities = 159/396 (40%), Positives = 190/396 (47%), Gaps = 63/396 (15%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PGP G RGL   +G  G  G+ G RG DG PG  G  GP G  G  G PGA    G K
Sbjct: 318  GSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGA---PGAK 374

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRG---APGQYGEKGFP 1511
            G +GP G  G +G  G  GE G  G PG  G  G+PG+ G PG++G   APG  G  GFP
Sbjct: 375  GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP 434

Query: 1512 GDPGNPGQNNNI-----KGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVS 1566
            G  G PG          KGQ G  G  G +G  G KG  G    +G+ G  G+ G RG  
Sbjct: 435  GPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGAR 494

Query: 1567 GEPGNPGPTGT---------------------------LGAEGLQGPQGSQGNPGRKGEK 1599
            GEPG  GP G                             G  GL GP+G+ G+PGR GE 
Sbjct: 495  GEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP 554

Query: 1600 GSQGQK---------GPQGSPGLMGAKGSTGR---PGLLGKKGEPGLPGDLGPVGQTGQR 1647
            G  G +         GPQG  G  GA G  GR   PG  G +G+PG+ G  GP G  G+ 
Sbjct: 555  GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEP 614

Query: 1648 GRQGDSGIPGY-------GQMGRKGVKGPRGFPGDAGQKGDIGNP------GIPGGPGPK 1694
            G+ G+ G+PG        G+ G  G  GP G  G AG++G+ G P      G+PG PGP 
Sbjct: 615  GKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPP 674

Query: 1695 GFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
            G  G     G+ GE G+ GL GP G+RG  G  G P
Sbjct: 675  GEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSP 710



 Score =  257 bits (657), Expect = 9e-68
 Identities = 154/375 (41%), Positives = 192/375 (51%), Gaps = 47/375 (12%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPG------AW 1448
            G+ GP G  G     G  GL G+RG  G  G+ G +G  GP G  G  G PG      A 
Sbjct: 537  GLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGAR 596

Query: 1449 GQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPG---------SR 1499
            GQ G+ GF GPKG +G+ G  G  G  G  G  G+ G+ G+ G+ G PG          +
Sbjct: 597  GQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQ 656

Query: 1500 GAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQ 1559
            GAPG  G +G PG PG PG+     G +G  GE G  G  G +G +G P  RGS G +G 
Sbjct: 657  GAPGPSGFQGLPGPPGPPGEGGK-PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGL 715

Query: 1560 RGLRGVSGEPGNPGP---TGTLGAEGLQGPQGSQGNPGR---------KGEKGSQGQKGP 1607
            +G RG+ G PG  GP   +G  G  G QGP G QG PG          KG++G  G+KGP
Sbjct: 716  QGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGP 775

Query: 1608 QGSPGLMGAKGST------GRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG---- 1657
            +G+PG  G +G T      G  G  G+KGE G PG  G  G  G  G +G++G PG    
Sbjct: 776  EGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGF 835

Query: 1658 YGQMGRKGVKGPRGFPGDAGQKGDIGNP---GIPGGPGPKGFRGLALTVGLKGEEGSRGL 1714
             G  G  G  G +G  G+AGQKGD G P   G  G PGP+G        G+ G +G+RG 
Sbjct: 836  AGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQG------PTGVTGPKGARGA 889

Query: 1715 PGPPGQRGIKGMAGQ 1729
             GPPG  G  G AG+
Sbjct: 890  QGPPGATGFPGAAGR 904



 Score =  256 bits (654), Expect = 2e-67
 Identities = 152/371 (40%), Positives = 187/371 (50%), Gaps = 20/371 (5%)

Query: 1371 GKKLSQYLGNIAERTCCCTFCKCPGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVR 1430
            G   +Q  G   E+          G  GP G RG     G+ G +G +G+ GE G PGV 
Sbjct: 177  GNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVS 236

Query: 1431 GDTGPQGDKGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDP 1490
            G  GP+G  G  G PG  G+ G  G +G +G  G  G  G  G  G    PG+KG +G P
Sbjct: 237  GPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPG---LPGVKGHRGYP 293

Query: 1491 GSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSS 1550
            G  G+ G  GAPG  GE G PG+ G+PG      G +G  GE+GR G +G  G +G+   
Sbjct: 294  GLDGAKGEAGAPGVKGESGSPGENGSPGP----MGPRGLPGERGRTGPAGAAGARGNDGQ 349

Query: 1551 RGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGS 1610
             G  G  G  G  G  G PG PG  G  G  G +GP+G+QG  G  G  GS G  G  G+
Sbjct: 350  PGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGN 409

Query: 1611 P---GLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG-------YGQ 1660
            P   G+ GAKGS G PG+ G  G PG  G  GP G TG  G +G +G PG        G 
Sbjct: 410  PGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGP 469

Query: 1661 MGRKGVKGPRGFPGDAGQKGDIGNPGIPGGP---GPKGFRGLALTVGLKGEEGSRGLPGP 1717
             G  G  GP+G PG AG++G  G  G PGG    GP G RG     G  G++G  G  G 
Sbjct: 470  KGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGA 529

Query: 1718 PGQRGIKGMAG 1728
            PG+RG  G+AG
Sbjct: 530  PGERGPSGLAG 540



 Score =  255 bits (651), Expect = 4e-67
 Identities = 154/369 (41%), Positives = 187/369 (50%), Gaps = 33/369 (8%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGV---RGDTGPQGDKGIAGCPGAWG- 1449
            PG+ GP G RG    +GS G +G +G RG  G PG    +G +GP G  G  G PG  G 
Sbjct: 692  PGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGM 751

Query: 1450 --QKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGI---------------KGEKGDPGS 1492
              ++G  G +GPKG  GD G  G +G  G  G  G+               KGE G PG 
Sbjct: 752  PGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGP 811

Query: 1493 QGSPGSRGAPGQYGEKGFPGDPG--NPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSS 1550
             GS G+RGAPG+ GE G PG  G   P   +   G KG +GE G++G +G  G QG   +
Sbjct: 812  AGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGA 871

Query: 1551 RGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGS 1610
             G +G  G  G +G  G  G PG TG  GA G  GP GS GNPG  G  G  G+ GP+G+
Sbjct: 872  PGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA 931

Query: 1611 PGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGVKGP 1669
             G  G  G  G PGL G  G PG  G+ G  G +G  G  G  G+ G  G +G  G +G 
Sbjct: 932  RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGE 991

Query: 1670 RGFPGDAGQKGDIGNPGIPGG------PGPKGFRGLALTVGLKGEEGSRGLPGPPGQ--- 1720
            RGFPG  G  G+ G  G PG       PGP G  GL    G  G EGS G  GPPG+   
Sbjct: 992  RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGA 1051

Query: 1721 RGIKGMAGQ 1729
             G+KG  G+
Sbjct: 1052 AGVKGDRGE 1060



 Score =  252 bits (644), Expect = 3e-66
 Identities = 151/370 (40%), Positives = 178/370 (48%), Gaps = 36/370 (9%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PGP G RG     G  G  G +G  GE G  G +G  G  G +G+ G  G  G  G 
Sbjct: 587  PGPPGPQGARG---QPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP 643

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAP---GQYGEKGF 1510
             G +GP G  G+ G  G  G +G  G PG  GE G PG QG PG  GAP   G  GE+GF
Sbjct: 644  PGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 703

Query: 1511 PGDPGNPGQNN-----------NIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQ 1559
            PG+ G+PG                 G KG+ G  G  G  G  G+QG P  RG+ G  G 
Sbjct: 704  PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP 763

Query: 1560 RGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGA--- 1616
            +G RG  GE G  G  G  G  GL GP G  G  G  GEKG  G  GP GS G  GA   
Sbjct: 764  KGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGE 823

Query: 1617 KGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG----------------YGQ 1660
            +G TG PG  G  G PG  G  G  G+ G+ G++GD+G PG                 G 
Sbjct: 824  RGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGP 883

Query: 1661 MGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQ 1720
             G +G +GP G  G  G  G +G PG  G PGP G  G +   G KG  G  G PG  G+
Sbjct: 884  KGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 943

Query: 1721 RGIKGMAGQP 1730
             G++G AG P
Sbjct: 944  PGLQGPAGPP 953



 Score =  250 bits (639), Expect = 1e-65
 Identities = 145/364 (39%), Positives = 180/364 (49%), Gaps = 30/364 (8%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRG------EDGNPGVRGDTGPQGDKGIAGCPGAW 1448
            G PGP G+ G +   G +G  G  G  G       DG PG +G+ G  G KG AG PG  
Sbjct: 807  GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 866

Query: 1449 GQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGE- 1507
            G  G  G  GP G  G  G  G  G  G  GFPG  G  G PGS G+PG  G PG  G+ 
Sbjct: 867  GPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKD 926

Query: 1508 --KGFPGDPGNPGQNNN--IKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLR 1563
              KG  GD G PG+     ++G  G  GE+G  G  G  G +G P  +G  G+ G  GL 
Sbjct: 927  GPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLP 986

Query: 1564 GVSGE---PGNPGPTGTLGAEGLQGPQGSQGNPG------------RKGEKGSQGQKGPQ 1608
            G  GE   PG PGP+G  G +G  G  G +G PG              G +GS G  GP 
Sbjct: 987  GQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPP 1046

Query: 1609 GSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG----YGQMGRK 1664
            G  G  G KG  G  G +G  G PG PG  GP G TG++G +G++G  G     G  G +
Sbjct: 1047 GRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGAR 1106

Query: 1665 GVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIK 1724
            G++GP+G  GD G+ G+ G  G+ G  G  G +GL    G  G++G+ G  GP G RG  
Sbjct: 1107 GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPP 1166

Query: 1725 GMAG 1728
            G  G
Sbjct: 1167 GPVG 1170



 Score =  249 bits (637), Expect = 2e-65
 Identities = 147/349 (42%), Positives = 179/349 (51%), Gaps = 20/349 (5%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PG  G  G +   G  GL G +G  GE G  G+ G  G  GD G  G PG  G +GL 
Sbjct: 504  GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLT 563

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGA---PGQYGEKGFP 1511
            G  G  G  G  G  G  GE+G  G PG +G +G PG  G PG +GA   PG+ GEKG P
Sbjct: 564  GRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLP 623

Query: 1512 GDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGN 1571
            G PG  G      G+ G+ G  G  G +G++G QG+P   G +G  G  G  G  G+PG+
Sbjct: 624  GAPGLRGLPGK-DGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGD 682

Query: 1572 PGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGL------MGAKGSTGRPGL 1625
             G  G  GA GL GP+G +G PG +G  G+QG +GP+G PG        GA G  G PG 
Sbjct: 683  QGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGA 742

Query: 1626 LGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG----YGQMGRKGVKGPRGFPGDAGQKGD 1681
             G  G  G+PG+ G  G  G +G +GD G  G     G+ G +G+ GP G PG AG  G+
Sbjct: 743  QGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGE 802

Query: 1682 IGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
             G  G PG  G  G R      G  GE G  G PGP G  G  G  GQP
Sbjct: 803  KGEVGPPGPAGSAGAR------GAPGERGETGPPGPAGFAGPPGADGQP 845



 Score =  242 bits (617), Expect = 4e-63
 Identities = 145/352 (41%), Positives = 176/352 (50%), Gaps = 17/352 (4%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQG---DKGIAGCPGAWGQ 1450
            PG  GP G  G    +G +G +G  G  G  G PG RG  G +G     G+AG  GA G+
Sbjct: 473  PGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGE 532

Query: 1451 KGLKGFSGPKGGHGDDGIDG---LDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQ--- 1504
            +G  G +GPKG +GD G  G   L G  G  G PG  G +G  G  G+PG  G PG    
Sbjct: 533  RGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGP 592

Query: 1505 YGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRG 1564
             G +G PG  G PG      G+ G  GE+G  G  G +G+ G     G+ G  G  G  G
Sbjct: 593  QGARGQPGVMGFPGP-KGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAG 651

Query: 1565 VSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRK---GEKGSQGQKGPQGSPGLMGAKGSTG 1621
              GE G PGP+G  G  G  GP G  G PG +   GE G+ G  GP+G  G  G +GS G
Sbjct: 652  ERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPG 711

Query: 1622 RPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGY----GQMGRKGVKGPRGFPGDAG 1677
              GL G +G PG PG  GP G +G  G  G  G PG     G+ G  G+ GP+G  GD G
Sbjct: 712  AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVG 771

Query: 1678 QKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQ 1729
            +KG  G PG  GG G  G  G     G  GE+G  G PGP G  G +G  G+
Sbjct: 772  EKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGE 823



 Score =  241 bits (616), Expect = 5e-63
 Identities = 147/365 (40%), Positives = 169/365 (46%), Gaps = 30/365 (8%)

Query: 1387 CCTFCK-----CPGIPGPHGTRGLQA-MKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKG 1440
            CC  C        G PGP G +G    +K   G KG  G +G  G  G RGD G +G+KG
Sbjct: 85   CCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKG 144

Query: 1441 IAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPG------------IKGEKG 1488
              G  G  G+ G  G  GP G  G  G  GL G        G            ++G  G
Sbjct: 145  APGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMG 204

Query: 1489 DPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSP 1548
              G +G PG  GAPG  G +G PG+PG PG    + G  G +G  G  G+ G  G  G P
Sbjct: 205  PMGPRGPPGPAGAPGPQGFQGNPGEPGEPG----VSGPMGPRGPPGPPGKPGDDGEAGKP 260

Query: 1549 SSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQK--- 1605
               G RG  G +G RG  G PG PG  G  G  GL G +G  G PG KGE GS G+    
Sbjct: 261  GKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSP 320

Query: 1606 GPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKG 1665
            GP G  GL G +G TG  G  G +G  G PG  GP G  G  G  G  G P     G KG
Sbjct: 321  GPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAP-----GAKG 375

Query: 1666 VKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKG 1725
              GP G  G  G +G  G PG PG PGP G  G   T G+ G +GS G PG  G  G  G
Sbjct: 376  EAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPG 435

Query: 1726 MAGQP 1730
              G P
Sbjct: 436  PRGPP 440



 Score =  241 bits (616), Expect = 5e-63
 Identities = 144/341 (42%), Positives = 173/341 (50%), Gaps = 17/341 (4%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKG---------SRGHRGEDGNPGVRGDTGPQGDKGIAGCP 1445
            G+ GP G RG Q   G+ G  G         S G+ G  G PG  G  GP+G +G +G P
Sbjct: 879  GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP 938

Query: 1446 GAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQY 1505
            G  G+ GL+G +GP G  G+ G DG  G EG  G  G+ G++G  G  G  G RG PG  
Sbjct: 939  GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLP 998

Query: 1506 GEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGV 1565
            G  G PG  G PG + + +G  G  G  G  G +G+ G +GSP + G  GR+G  G++G 
Sbjct: 999  GPSGEPGKQGAPGASGD-RGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGD 1057

Query: 1566 SGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGL 1625
             GE G  G  G  G  G  GP G  G  G +GE G+QG  GP G  G   A+G  G  G 
Sbjct: 1058 RGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAG---ARGIQGPQGP 1114

Query: 1626 LGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG----YGQMGRKGVKGPRGFPGDAGQKGD 1681
             G KGE G PG+ G  G  G  G QG  G PG     G  G  G  GPRG PG  G  G 
Sbjct: 1115 RGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGK 1174

Query: 1682 IGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRG 1722
             G  GIPG  GP G RG +   G  G  G+ G PGPPG  G
Sbjct: 1175 DGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG 1215



 Score =  239 bits (610), Expect = 3e-62
 Identities = 147/366 (40%), Positives = 175/366 (47%), Gaps = 30/366 (8%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG  GP G +G +  +G +G KG+ G RG DG PG  G+ GP G  G  G PG  G    
Sbjct: 122  PGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAA 181

Query: 1454 K---GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAP---GQYGE 1507
            +   GF    GG     + G  G  G  G PG  G  G  G QG+PG  G P   G  G 
Sbjct: 182  QMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGP 241

Query: 1508 KGFPGDPGNPGQNNNI-----------KGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGR 1556
            +G PG PG PG +               G +G++G  G  G  G KG +G P   G++G 
Sbjct: 242  RGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGE 301

Query: 1557 EGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGA 1616
             G  G++G SG PG  G  G +G  GL G +G  G  G  G +G+ GQ GP G PG +G 
Sbjct: 302  AGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGP 361

Query: 1617 KGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG-YGQMGRKGVKGPRGFPGD 1675
             G  G PG  G KGE G  G  GP G  G RG  G  G PG  G  G  G  G  G  G 
Sbjct: 362  AGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGS 421

Query: 1676 AGQKGDIGNPGIPG--GP----------GPKGFRGLALTVGLKGEEGSRGLPGPPGQRGI 1723
            AG  G  G PG PG  GP          GPKG  G     G KGE+G +G PGP G +G 
Sbjct: 422  AGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGA 481

Query: 1724 KGMAGQ 1729
             G AG+
Sbjct: 482  PGPAGE 487



 Score =  189 bits (479), Expect = 4e-47
 Identities = 110/261 (42%), Positives = 133/261 (50%), Gaps = 17/261 (6%)

Query: 1394 PGIPGPHGT------RGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGA 1447
            PG  GP G       +GL   +G  GL G RG RG  G PG  G+ G QG  G +G  G 
Sbjct: 959  PGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGP 1018

Query: 1448 WGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGE 1507
             G  G  G +GP G  G +G  G DG  G  G  G+KG++G+ G+ G+PG+ G PG  G 
Sbjct: 1019 PGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGP 1078

Query: 1508 KGFPGDPGNPGQNN-----NIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGL 1562
             G  G  G+ G+          G  G++G QG QG  G KG  G P   G RG +G RG 
Sbjct: 1079 AGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEP---GERGLKGHRGF 1135

Query: 1563 RGVSGEPGNPGPTGTLGAEGLQGPQGSQGNP---GRKGEKGSQGQKGPQGSPGLMGAKGS 1619
             G+ G PG PGP+G  GA G  GP G +G P   G  G+ G+ G  GP G PG  G  G 
Sbjct: 1136 TGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGE 1195

Query: 1620 TGRPGLLGKKGEPGLPGDLGP 1640
            TG  G  G  G PG PG  GP
Sbjct: 1196 TGPAGPPGNPGPPGPPGPPGP 1216



 Score =  179 bits (454), Expect = 3e-44
 Identities = 105/269 (39%), Positives = 128/269 (47%), Gaps = 11/269 (4%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G  GP G +GL   +G  GL G RG RG  G PG  G+ G QG  G +G  G  G  G  
Sbjct: 966  GAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPP 1025

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDP 1514
            G +GP G  G +G  G DG  G  G  G+KG++G+ G+ G+PG+ G PG  G  G  G  
Sbjct: 1026 GLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQ 1085

Query: 1515 GNPGQNN-----NIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEP 1569
            G+ G+          G  G++G QG QG  G KG  G P  RG +G  G  GL+G+ G P
Sbjct: 1086 GDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPP 1145

Query: 1570 GN------PGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRP 1623
            G        GP G  G  G  GP G  G  G  G  G  G  GP+G  G  G  G  G P
Sbjct: 1146 GPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNP 1205

Query: 1624 GLLGKKGEPGLPGDLGPVGQTGQRGRQGD 1652
            G  G  G PG   D+      G R +  D
Sbjct: 1206 GPPGPPGPPGPGIDMSAFAGLGPREKGPD 1234



 Score =  112 bits (280), Expect = 5e-24
 Identities = 77/211 (36%), Positives = 96/211 (45%), Gaps = 11/211 (5%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PGP G  G Q  +G  G +G  G  G  G  G++G  GP+GDKG AG PG  G KG 
Sbjct: 1073 PGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGH 1132

Query: 1454 KGFS------GPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAP---GQ 1504
            +GF+      GP G  GD G  G  G  G  G PG  G  G  G+ G PG  G P   G+
Sbjct: 1133 RGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGR 1192

Query: 1505 YGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRG 1564
             GE G  G PGNPG      G  G   +       G +  +G    +  R  +   GLR 
Sbjct: 1193 SGETGPAGPPGNPGPPGP-PGPPGPGIDMSAFAGLGPR-EKGPDPLQYMRADQAAGGLRQ 1250

Query: 1565 VSGEPGNPGPTGTLGAEGLQGPQGSQGNPGR 1595
               E      +     E ++ P+GS+ NP R
Sbjct: 1251 HDAEVDATLKSLNNQIESIRSPEGSRKNPAR 1281



 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 44/154 (28%), Positives = 58/154 (37%), Gaps = 10/154 (6%)

Query: 1390 FCKCPGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWG 1449
            F    G+PGP G        G QG  G  G  G  G PG  G +G  G  GI G  G  G
Sbjct: 1135 FTGLQGLPGPPGP------SGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1188

Query: 1450 QKGLKGFSGPKGGHGDDGIDGLDGEEG----CHGFPGIKGEKGDPGSQGSPGSRGAPGQY 1505
             +G  G +GP G  G+ G  G  G  G       F G+   +  P       +  A G  
Sbjct: 1189 PRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAGGL 1248

Query: 1506 GEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRS 1539
             +     D      NN I+  +  +G +    R+
Sbjct: 1249 RQHDAEVDATLKSLNNQIESIRSPEGSRKNPART 1282


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score =  269 bits (688), Expect = 2e-71
 Identities = 154/346 (44%), Positives = 175/346 (50%), Gaps = 15/346 (4%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PG  G  G Q + G  G  G  G RGE G PG RG  G QG +G  G PG  G  G 
Sbjct: 602  PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGP 661

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD 1513
            KG SGP G  G  G  GL G  G  G  GI G KGD G  G  G  GAPG+ G +G  G 
Sbjct: 662  KGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGP 721

Query: 1514 PGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRG--------- 1564
             G PG      G  G KGE G  G +G  G +G+P  RG  G  G  G  G         
Sbjct: 722  IGPPGP----AGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPG 777

Query: 1565 VSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPG 1624
              GE G  G  G  GA G QGP G+ G  G  G  G +G +G QG PG  G  G+ GR G
Sbjct: 778  AKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVG 837

Query: 1625 LLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGN 1684
              G  G PG PG  GP G+ G +G +GDSG P  G+ G  G++GP G PG+ G+ GD G 
Sbjct: 838  PPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP--GRAGEPGLQGPAGPPGEKGEPGDDGP 895

Query: 1685 PGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
             G  G PGP+G  G    VGL G+ G RG PG PG  G  G  G P
Sbjct: 896  SGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAP 941



 Score =  258 bits (660), Expect = 4e-68
 Identities = 150/371 (40%), Positives = 184/371 (49%), Gaps = 39/371 (10%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG+ GP G RG     G  G  G  G  G+ G  G RG  GPQG +G  G PG  G KG 
Sbjct: 164  PGVSGPMGPRG---PPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGH 220

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGC---HGFPGIKGEKGDPGSQG---------------S 1495
            +G+ G  G  G+ G  G+ GE G    +G PG  G +G PG +G                
Sbjct: 221  RGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQ 280

Query: 1496 PGSRGAPGQYGEKGFPGDPGNPGQNNNI--------KGQKGSKGEQGRQGRSGQKGVQGS 1547
            PG  G PG  G  G PG PG PG             +G +G +GE G  G  G  G  G+
Sbjct: 281  PGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGN 340

Query: 1548 PSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGP 1607
            P + G  G +G  G  G++G PG PGP G  G +G  GP G +G  G  G  G +G++GP
Sbjct: 341  PGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGP 400

Query: 1608 QGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGV 1666
            +G PG  G +G+ G  G  GK+G  G PG +GP+G  G+RG  G+ G PG  G  G KG 
Sbjct: 401  KGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGA 460

Query: 1667 KGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLA---------LTVGLKGEEGSRGLPGP 1717
             G RG  G AG KG  G+PG PG PG  G RGL            VG  G  G  G PGP
Sbjct: 461  PGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP 520

Query: 1718 PGQRGIKGMAG 1728
            PG +G +G  G
Sbjct: 521  PGPQGARGQPG 531



 Score =  258 bits (658), Expect = 7e-68
 Identities = 159/396 (40%), Positives = 190/396 (47%), Gaps = 63/396 (15%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PGP G RGL   +G  G  G+ G RG DG PG  G  GP G  G  G PGA    G K
Sbjct: 249  GSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGA---PGAK 305

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRG---APGQYGEKGFP 1511
            G +GP G  G +G  G  GE G  G PG  G  G+PG+ G PG++G   APG  G  GFP
Sbjct: 306  GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP 365

Query: 1512 GDPGNPGQNNNI-----KGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVS 1566
            G  G PG          KGQ G  G  G +G  G KG  G    +G+ G  G+ G RG  
Sbjct: 366  GPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGAR 425

Query: 1567 GEPGNPGPTGT---------------------------LGAEGLQGPQGSQGNPGRKGEK 1599
            GEPG  GP G                             G  GL GP+G+ G+PGR GE 
Sbjct: 426  GEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP 485

Query: 1600 GSQGQK---------GPQGSPGLMGAKGSTGR---PGLLGKKGEPGLPGDLGPVGQTGQR 1647
            G  G +         GPQG  G  GA G  GR   PG  G +G+PG+ G  GP G  G+ 
Sbjct: 486  GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEP 545

Query: 1648 GRQGDSGIPGY-------GQMGRKGVKGPRGFPGDAGQKGDIGNP------GIPGGPGPK 1694
            G+ G+ G+PG        G+ G  G  GP G  G AG++G+ G P      G+PG PGP 
Sbjct: 546  GKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPP 605

Query: 1695 GFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
            G  G     G+ GE G+ GL GP G+RG  G  G P
Sbjct: 606  GEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSP 641



 Score =  257 bits (657), Expect = 9e-68
 Identities = 154/375 (41%), Positives = 192/375 (51%), Gaps = 47/375 (12%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPG------AW 1448
            G+ GP G  G     G  GL G+RG  G  G+ G +G  GP G  G  G PG      A 
Sbjct: 468  GLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGAR 527

Query: 1449 GQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPG---------SR 1499
            GQ G+ GF GPKG +G+ G  G  G  G  G  G+ G+ G+ G+ G PG          +
Sbjct: 528  GQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQ 587

Query: 1500 GAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQ 1559
            GAPG  G +G PG PG PG+     G +G  GE G  G  G +G +G P  RGS G +G 
Sbjct: 588  GAPGPSGFQGLPGPPGPPGEGGK-PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGL 646

Query: 1560 RGLRGVSGEPGNPGP---TGTLGAEGLQGPQGSQGNPGR---------KGEKGSQGQKGP 1607
            +G RG+ G PG  GP   +G  G  G QGP G QG PG          KG++G  G+KGP
Sbjct: 647  QGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGP 706

Query: 1608 QGSPGLMGAKGST------GRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG---- 1657
            +G+PG  G +G T      G  G  G+KGE G PG  G  G  G  G +G++G PG    
Sbjct: 707  EGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGF 766

Query: 1658 YGQMGRKGVKGPRGFPGDAGQKGDIGNP---GIPGGPGPKGFRGLALTVGLKGEEGSRGL 1714
             G  G  G  G +G  G+AGQKGD G P   G  G PGP+G        G+ G +G+RG 
Sbjct: 767  AGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQG------PTGVTGPKGARGA 820

Query: 1715 PGPPGQRGIKGMAGQ 1729
             GPPG  G  G AG+
Sbjct: 821  QGPPGATGFPGAAGR 835



 Score =  256 bits (654), Expect = 2e-67
 Identities = 152/371 (40%), Positives = 187/371 (50%), Gaps = 20/371 (5%)

Query: 1371 GKKLSQYLGNIAERTCCCTFCKCPGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVR 1430
            G   +Q  G   E+          G  GP G RG     G+ G +G +G+ GE G PGV 
Sbjct: 108  GNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVS 167

Query: 1431 GDTGPQGDKGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDP 1490
            G  GP+G  G  G PG  G+ G  G +G +G  G  G  G  G  G    PG+KG +G P
Sbjct: 168  GPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPG---LPGVKGHRGYP 224

Query: 1491 GSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSS 1550
            G  G+ G  GAPG  GE G PG+ G+PG      G +G  GE+GR G +G  G +G+   
Sbjct: 225  GLDGAKGEAGAPGVKGESGSPGENGSPGP----MGPRGLPGERGRTGPAGAAGARGNDGQ 280

Query: 1551 RGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGS 1610
             G  G  G  G  G  G PG PG  G  G  G +GP+G+QG  G  G  GS G  G  G+
Sbjct: 281  PGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGN 340

Query: 1611 P---GLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG-------YGQ 1660
            P   G+ GAKGS G PG+ G  G PG  G  GP G TG  G +G +G PG        G 
Sbjct: 341  PGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGP 400

Query: 1661 MGRKGVKGPRGFPGDAGQKGDIGNPGIPGGP---GPKGFRGLALTVGLKGEEGSRGLPGP 1717
             G  G  GP+G PG AG++G  G  G PGG    GP G RG     G  G++G  G  G 
Sbjct: 401  KGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGA 460

Query: 1718 PGQRGIKGMAG 1728
            PG+RG  G+AG
Sbjct: 461  PGERGPSGLAG 471



 Score =  255 bits (651), Expect = 4e-67
 Identities = 154/369 (41%), Positives = 187/369 (50%), Gaps = 33/369 (8%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGV---RGDTGPQGDKGIAGCPGAWG- 1449
            PG+ GP G RG    +GS G +G +G RG  G PG    +G +GP G  G  G PG  G 
Sbjct: 623  PGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGM 682

Query: 1450 --QKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGI---------------KGEKGDPGS 1492
              ++G  G +GPKG  GD G  G +G  G  G  G+               KGE G PG 
Sbjct: 683  PGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGP 742

Query: 1493 QGSPGSRGAPGQYGEKGFPGDPG--NPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSS 1550
             GS G+RGAPG+ GE G PG  G   P   +   G KG +GE G++G +G  G QG   +
Sbjct: 743  AGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGA 802

Query: 1551 RGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGS 1610
             G +G  G  G +G  G  G PG TG  GA G  GP GS GNPG  G  G  G+ GP+G+
Sbjct: 803  PGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA 862

Query: 1611 PGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGVKGP 1669
             G  G  G  G PGL G  G PG  G+ G  G +G  G  G  G+ G  G +G  G +G 
Sbjct: 863  RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGE 922

Query: 1670 RGFPGDAGQKGDIGNPGIPGG------PGPKGFRGLALTVGLKGEEGSRGLPGPPGQ--- 1720
            RGFPG  G  G+ G  G PG       PGP G  GL    G  G EGS G  GPPG+   
Sbjct: 923  RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGA 982

Query: 1721 RGIKGMAGQ 1729
             G+KG  G+
Sbjct: 983  AGVKGDRGE 991



 Score =  252 bits (644), Expect = 3e-66
 Identities = 151/370 (40%), Positives = 178/370 (48%), Gaps = 36/370 (9%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PGP G RG     G  G  G +G  GE G  G +G  G  G +G+ G  G  G  G 
Sbjct: 518  PGPPGPQGARG---QPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP 574

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAP---GQYGEKGF 1510
             G +GP G  G+ G  G  G +G  G PG  GE G PG QG PG  GAP   G  GE+GF
Sbjct: 575  PGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 634

Query: 1511 PGDPGNPGQNN-----------NIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQ 1559
            PG+ G+PG                 G KG+ G  G  G  G  G+QG P  RG+ G  G 
Sbjct: 635  PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP 694

Query: 1560 RGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGA--- 1616
            +G RG  GE G  G  G  G  GL GP G  G  G  GEKG  G  GP GS G  GA   
Sbjct: 695  KGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGE 754

Query: 1617 KGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG----------------YGQ 1660
            +G TG PG  G  G PG  G  G  G+ G+ G++GD+G PG                 G 
Sbjct: 755  RGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGP 814

Query: 1661 MGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQ 1720
             G +G +GP G  G  G  G +G PG  G PGP G  G +   G KG  G  G PG  G+
Sbjct: 815  KGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 874

Query: 1721 RGIKGMAGQP 1730
             G++G AG P
Sbjct: 875  PGLQGPAGPP 884



 Score =  250 bits (639), Expect = 1e-65
 Identities = 145/364 (39%), Positives = 180/364 (49%), Gaps = 30/364 (8%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRG------EDGNPGVRGDTGPQGDKGIAGCPGAW 1448
            G PGP G+ G +   G +G  G  G  G       DG PG +G+ G  G KG AG PG  
Sbjct: 738  GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 797

Query: 1449 GQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGE- 1507
            G  G  G  GP G  G  G  G  G  G  GFPG  G  G PGS G+PG  G PG  G+ 
Sbjct: 798  GPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKD 857

Query: 1508 --KGFPGDPGNPGQNNN--IKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLR 1563
              KG  GD G PG+     ++G  G  GE+G  G  G  G +G P  +G  G+ G  GL 
Sbjct: 858  GPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLP 917

Query: 1564 GVSGE---PGNPGPTGTLGAEGLQGPQGSQGNPG------------RKGEKGSQGQKGPQ 1608
            G  GE   PG PGP+G  G +G  G  G +G PG              G +GS G  GP 
Sbjct: 918  GQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPP 977

Query: 1609 GSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG----YGQMGRK 1664
            G  G  G KG  G  G +G  G PG PG  GP G TG++G +G++G  G     G  G +
Sbjct: 978  GRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGAR 1037

Query: 1665 GVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIK 1724
            G++GP+G  GD G+ G+ G  G+ G  G  G +GL    G  G++G+ G  GP G RG  
Sbjct: 1038 GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPP 1097

Query: 1725 GMAG 1728
            G  G
Sbjct: 1098 GPVG 1101



 Score =  249 bits (637), Expect = 2e-65
 Identities = 147/349 (42%), Positives = 179/349 (51%), Gaps = 20/349 (5%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PG  G  G +   G  GL G +G  GE G  G+ G  G  GD G  G PG  G +GL 
Sbjct: 435  GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLT 494

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGA---PGQYGEKGFP 1511
            G  G  G  G  G  G  GE+G  G PG +G +G PG  G PG +GA   PG+ GEKG P
Sbjct: 495  GRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLP 554

Query: 1512 GDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGN 1571
            G PG  G      G+ G+ G  G  G +G++G QG+P   G +G  G  G  G  G+PG+
Sbjct: 555  GAPGLRGLPGK-DGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGD 613

Query: 1572 PGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGL------MGAKGSTGRPGL 1625
             G  G  GA GL GP+G +G PG +G  G+QG +GP+G PG        GA G  G PG 
Sbjct: 614  QGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGA 673

Query: 1626 LGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG----YGQMGRKGVKGPRGFPGDAGQKGD 1681
             G  G  G+PG+ G  G  G +G +GD G  G     G+ G +G+ GP G PG AG  G+
Sbjct: 674  QGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGE 733

Query: 1682 IGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
             G  G PG  G  G R      G  GE G  G PGP G  G  G  GQP
Sbjct: 734  KGEVGPPGPAGSAGAR------GAPGERGETGPPGPAGFAGPPGADGQP 776



 Score =  243 bits (620), Expect = 2e-63
 Identities = 150/368 (40%), Positives = 176/368 (47%), Gaps = 33/368 (8%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSR---GHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQK 1451
            G PGP G  G Q  +G +G KG +   G RG DG PG  G+ GP G  G  G PG  G  
Sbjct: 51   GPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNF 110

Query: 1452 GLK---GF------------SGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSP 1496
              +   GF             GP G  G  G  G  G  G  GF G  GE G+PG  G  
Sbjct: 111  AAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPM 170

Query: 1497 GSRGAPGQYGEKGFPGDPGNPGQ--NNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSR 1554
            G RG PG  G+ G  G+ G PG+       G +G++G  G  G  G KG +G P   G++
Sbjct: 171  GPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAK 230

Query: 1555 GREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLM 1614
            G  G  G++G SG PG  G  G +G  GL G +G  G  G  G +G+ GQ GP G PG +
Sbjct: 231  GEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPV 290

Query: 1615 GAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG-YGQMGRKGVKGPRGFP 1673
            G  G  G PG  G KGE G  G  GP G  G RG  G  G PG  G  G  G  G  G  
Sbjct: 291  GPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAK 350

Query: 1674 GDAGQKGDIGNPGIPG--GP----------GPKGFRGLALTVGLKGEEGSRGLPGPPGQR 1721
            G AG  G  G PG PG  GP          GPKG  G     G KGE+G +G PGP G +
Sbjct: 351  GSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQ 410

Query: 1722 GIKGMAGQ 1729
            G  G AG+
Sbjct: 411  GAPGPAGE 418



 Score =  242 bits (617), Expect = 4e-63
 Identities = 145/352 (41%), Positives = 176/352 (50%), Gaps = 17/352 (4%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQG---DKGIAGCPGAWGQ 1450
            PG  GP G  G    +G +G +G  G  G  G PG RG  G +G     G+AG  GA G+
Sbjct: 404  PGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGE 463

Query: 1451 KGLKGFSGPKGGHGDDGIDG---LDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQ--- 1504
            +G  G +GPKG +GD G  G   L G  G  G PG  G +G  G  G+PG  G PG    
Sbjct: 464  RGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGP 523

Query: 1505 YGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRG 1564
             G +G PG  G PG      G+ G  GE+G  G  G +G+ G     G+ G  G  G  G
Sbjct: 524  QGARGQPGVMGFPGP-KGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAG 582

Query: 1565 VSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRK---GEKGSQGQKGPQGSPGLMGAKGSTG 1621
              GE G PGP+G  G  G  GP G  G PG +   GE G+ G  GP+G  G  G +GS G
Sbjct: 583  ERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPG 642

Query: 1622 RPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGY----GQMGRKGVKGPRGFPGDAG 1677
              GL G +G PG PG  GP G +G  G  G  G PG     G+ G  G+ GP+G  GD G
Sbjct: 643  AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVG 702

Query: 1678 QKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQ 1729
            +KG  G PG  GG G  G  G     G  GE+G  G PGP G  G +G  G+
Sbjct: 703  EKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGE 754



 Score =  241 bits (616), Expect = 5e-63
 Identities = 144/341 (42%), Positives = 173/341 (50%), Gaps = 17/341 (4%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKG---------SRGHRGEDGNPGVRGDTGPQGDKGIAGCP 1445
            G+ GP G RG Q   G+ G  G         S G+ G  G PG  G  GP+G +G +G P
Sbjct: 810  GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP 869

Query: 1446 GAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQY 1505
            G  G+ GL+G +GP G  G+ G DG  G EG  G  G+ G++G  G  G  G RG PG  
Sbjct: 870  GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLP 929

Query: 1506 GEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGV 1565
            G  G PG  G PG + + +G  G  G  G  G +G+ G +GSP + G  GR+G  G++G 
Sbjct: 930  GPSGEPGKQGAPGASGD-RGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGD 988

Query: 1566 SGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGL 1625
             GE G  G  G  G  G  GP G  G  G +GE G+QG  GP G  G   A+G  G  G 
Sbjct: 989  RGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAG---ARGIQGPQGP 1045

Query: 1626 LGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG----YGQMGRKGVKGPRGFPGDAGQKGD 1681
             G KGE G PG+ G  G  G  G QG  G PG     G  G  G  GPRG PG  G  G 
Sbjct: 1046 RGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGK 1105

Query: 1682 IGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRG 1722
             G  GIPG  GP G RG +   G  G  G+ G PGPPG  G
Sbjct: 1106 DGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG 1146



 Score =  239 bits (609), Expect = 3e-62
 Identities = 140/340 (41%), Positives = 164/340 (48%), Gaps = 24/340 (7%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG  GP G +G +  +G +G KG+ G RG DG PG  G+ GP G  G  G PG  G    
Sbjct: 53   PGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGN--- 109

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD 1513
              F+    G       G D + G      ++G  G  G +G PG  GAPG  G +G PG+
Sbjct: 110  --FAAQMAG-------GFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGE 160

Query: 1514 PGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPG 1573
            PG PG    + G  G +G  G  G+ G  G  G P   G RG  G +G RG  G PG PG
Sbjct: 161  PGEPG----VSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPG 216

Query: 1574 PTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQK---GPQGSPGLMGAKGSTGRPGLLGKKG 1630
              G  G  GL G +G  G PG KGE GS G+    GP G  GL G +G TG  G  G +G
Sbjct: 217  VKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARG 276

Query: 1631 EPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGG 1690
              G PG  GP G  G  G  G  G P     G KG  GP G  G  G +G  G PG PG 
Sbjct: 277  NDGQPGPAGPPGPVGPAGGPGFPGAP-----GAKGEAGPTGARGPEGAQGPRGEPGTPGS 331

Query: 1691 PGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
            PGP G  G   T G+ G +GS G PG  G  G  G  G P
Sbjct: 332  PGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPP 371



 Score =  189 bits (479), Expect = 4e-47
 Identities = 110/261 (42%), Positives = 133/261 (50%), Gaps = 17/261 (6%)

Query: 1394 PGIPGPHGT------RGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGA 1447
            PG  GP G       +GL   +G  GL G RG RG  G PG  G+ G QG  G +G  G 
Sbjct: 890  PGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGP 949

Query: 1448 WGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGE 1507
             G  G  G +GP G  G +G  G DG  G  G  G+KG++G+ G+ G+PG+ G PG  G 
Sbjct: 950  PGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGP 1009

Query: 1508 KGFPGDPGNPGQNN-----NIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGL 1562
             G  G  G+ G+          G  G++G QG QG  G KG  G P   G RG +G RG 
Sbjct: 1010 AGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEP---GERGLKGHRGF 1066

Query: 1563 RGVSGEPGNPGPTGTLGAEGLQGPQGSQGNP---GRKGEKGSQGQKGPQGSPGLMGAKGS 1619
             G+ G PG PGP+G  GA G  GP G +G P   G  G+ G+ G  GP G PG  G  G 
Sbjct: 1067 TGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGE 1126

Query: 1620 TGRPGLLGKKGEPGLPGDLGP 1640
            TG  G  G  G PG PG  GP
Sbjct: 1127 TGPAGPPGNPGPPGPPGPPGP 1147



 Score =  179 bits (454), Expect = 3e-44
 Identities = 105/269 (39%), Positives = 128/269 (47%), Gaps = 11/269 (4%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G  GP G +GL   +G  GL G RG RG  G PG  G+ G QG  G +G  G  G  G  
Sbjct: 897  GAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPP 956

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDP 1514
            G +GP G  G +G  G DG  G  G  G+KG++G+ G+ G+PG+ G PG  G  G  G  
Sbjct: 957  GLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQ 1016

Query: 1515 GNPGQNN-----NIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEP 1569
            G+ G+          G  G++G QG QG  G KG  G P  RG +G  G  GL+G+ G P
Sbjct: 1017 GDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPP 1076

Query: 1570 GN------PGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRP 1623
            G        GP G  G  G  GP G  G  G  G  G  G  GP+G  G  G  G  G P
Sbjct: 1077 GPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNP 1136

Query: 1624 GLLGKKGEPGLPGDLGPVGQTGQRGRQGD 1652
            G  G  G PG   D+      G R +  D
Sbjct: 1137 GPPGPPGPPGPGIDMSAFAGLGPREKGPD 1165



 Score =  164 bits (415), Expect = 1e-39
 Identities = 100/254 (39%), Positives = 122/254 (48%), Gaps = 28/254 (11%)

Query: 1502 PGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRG 1561
            PG  G+KG PGD  +        G +G  GEQG +G  G KG +G+P   G RGR+G+ G
Sbjct: 31   PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAP---GPRGRDGEPG 87

Query: 1562 LRGVSGEPGNPGPTGTLG------------------------AEGLQGPQGSQGNPGRKG 1597
              G  G PG PGP G  G                         +G  GP G +G PG  G
Sbjct: 88   TPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAG 147

Query: 1598 EKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG 1657
              G QG +G  G PG  G  G  G  G  G  G+PG  G+ G  G+ G+RG  G  G  G
Sbjct: 148  APGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARG 207

Query: 1658 Y-GQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPG 1716
            + G  G  GVKG RG+PG  G KG+ G PG+ G  G  G  G    +G +G  G RG  G
Sbjct: 208  FPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTG 267

Query: 1717 PPGQRGIKGMAGQP 1730
            P G  G +G  GQP
Sbjct: 268  PAGAAGARGNDGQP 281



 Score =  124 bits (312), Expect = 9e-28
 Identities = 84/216 (38%), Positives = 98/216 (45%), Gaps = 19/216 (8%)

Query: 1518 GQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGT 1577
            GQ+    G KG KGE G        G +G P  +G  G +G RG RG  GE G P     
Sbjct: 25   GQDVRQPGPKGQKGEPG--DIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAP----- 77

Query: 1578 LGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGD 1637
                   GP+G  G PG  G  G  G  GP G PGL G   +    G   K G   L   
Sbjct: 78   -------GPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVM 130

Query: 1638 LGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFR 1697
             GP+G  G RG  G +G PG    G +G  G  G PG +G  G  G PG PG PG  G  
Sbjct: 131  QGPMGPMGPRGPPGPAGAPG--PQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEA 188

Query: 1698 GLALTVGLK---GEEGSRGLPGPPGQRGIKGMAGQP 1730
            G     G +   G +G+RG PG PG  G+KG  G P
Sbjct: 189  GKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYP 224



 Score =  112 bits (280), Expect = 5e-24
 Identities = 77/211 (36%), Positives = 96/211 (45%), Gaps = 11/211 (5%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PGP G  G Q  +G  G +G  G  G  G  G++G  GP+GDKG AG PG  G KG 
Sbjct: 1004 PGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGH 1063

Query: 1454 KGFS------GPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAP---GQ 1504
            +GF+      GP G  GD G  G  G  G  G PG  G  G  G+ G PG  G P   G+
Sbjct: 1064 RGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGR 1123

Query: 1505 YGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRG 1564
             GE G  G PGNPG      G  G   +       G +  +G    +  R  +   GLR 
Sbjct: 1124 SGETGPAGPPGNPGPPGP-PGPPGPGIDMSAFAGLGPR-EKGPDPLQYMRADQAAGGLRQ 1181

Query: 1565 VSGEPGNPGPTGTLGAEGLQGPQGSQGNPGR 1595
               E      +     E ++ P+GS+ NP R
Sbjct: 1182 HDAEVDATLKSLNNQIESIRSPEGSRKNPAR 1212



 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 44/154 (28%), Positives = 58/154 (37%), Gaps = 10/154 (6%)

Query: 1390 FCKCPGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWG 1449
            F    G+PGP G        G QG  G  G  G  G PG  G +G  G  GI G  G  G
Sbjct: 1066 FTGLQGLPGPPGP------SGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1119

Query: 1450 QKGLKGFSGPKGGHGDDGIDGLDGEEG----CHGFPGIKGEKGDPGSQGSPGSRGAPGQY 1505
             +G  G +GP G  G+ G  G  G  G       F G+   +  P       +  A G  
Sbjct: 1120 PRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAGGL 1179

Query: 1506 GEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRS 1539
             +     D      NN I+  +  +G +    R+
Sbjct: 1180 RQHDAEVDATLKSLNNQIESIRSPEGSRKNPART 1213


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score =  268 bits (686), Expect = 4e-71
 Identities = 159/357 (44%), Positives = 191/357 (53%), Gaps = 32/357 (8%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PG  G  GL    G+ G  G +G  G  GNPG+ G+ GP G  G  G PG  G+KG 
Sbjct: 1109 PGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGK 1168

Query: 1454 KG---FSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGF 1510
             G     GP G  G+ G  G  G  G  G PG+ G+KGD G  G PG+ G PG  GE GF
Sbjct: 1169 PGQDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGF 1227

Query: 1511 ---------PGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRG 1561
                     PG PG+PG    ++G KG+ G QG  GR G  G +G P      G  G  G
Sbjct: 1228 HGFPGVQGPPGPPGSPGPA--LEGPKGNPGPQGPPGRPGLPGPEGPP------GLPGNGG 1279

Query: 1562 LRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTG 1621
            ++G  G PG PG  G  G +G QGP G QGNPGR G  G +G  G  G PG  G KG +G
Sbjct: 1280 IKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSG 1339

Query: 1622 RPGLLGKKGEPGLPGDLGPVGQTGQRGR----QGDSGIPGY-GQMGRKGV---KGPRGFP 1673
             PG  G +GEPGL G  GP G  G  G+    +GD+G PG  GQ G KG+   +GP+G P
Sbjct: 1340 VPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLP 1399

Query: 1674 GDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
            G  G  GD G  G+PG  G  G +G     GL G+ G+RGL GPPG  G++G  G P
Sbjct: 1400 GPTGPPGDPGRNGLPGFDGAGGRKG---DPGLPGQPGTRGLDGPPGPDGLQGPPGPP 1453



 Score =  255 bits (651), Expect = 4e-67
 Identities = 164/410 (40%), Positives = 192/410 (46%), Gaps = 70/410 (17%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G PG  G  G+   KG QGL G  G  G  G PG+ G  GP+G+ G+ G PG  G  GLK
Sbjct: 967  GEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLK 1026

Query: 1455 G------FSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEK 1508
            G      F GP+G  G  G  G+ G+ G  G PG KG+KGDPG   S G  G PG  GE 
Sbjct: 1027 GTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGIS-SIGLPGLPGPKGEP 1085

Query: 1509 GFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGE 1568
            G PG PGNPG   ++ G  G  G  G  G  GQ G+ G P + G  G +G  G  G  G 
Sbjct: 1086 GLPGYPGNPGIKGSV-GDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGL 1144

Query: 1569 PGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKG-----------PQGSPGLMGAK 1617
            PG PGP G  G  G  GP G +G PG+ G  G  GQKG           P G PGL G K
Sbjct: 1145 PGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQK 1204

Query: 1618 GS------TGRPGLLGKKGEPGL--------------------------PGDLGPVGQTG 1645
            G        G PGL G KGEPG                           PG  GP G+ G
Sbjct: 1205 GDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPG 1264

Query: 1646 QRGRQGDSGIPGYGQM-GRKGVKGPRGFPGDAGQKGDIG------------------NPG 1686
              G +G  G+PG G + G KG  G  G PG  G KGD G                  +PG
Sbjct: 1265 LPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPG 1324

Query: 1687 IPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCD 1736
            +PG PG  G +G +   G  G EG  GL GPPG  G+ G +GQ +  + D
Sbjct: 1325 LPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGD 1374



 Score =  254 bits (649), Expect = 8e-67
 Identities = 167/393 (42%), Positives = 194/393 (49%), Gaps = 63/393 (16%)

Query: 1396 IPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPG---VRGDTGPQGDKGIAGCPGAWGQKG 1452
            +PGP G  GL   KG+ G KG RG  G  G PG   + G  GP+GD G  G PG  G  G
Sbjct: 755  LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPG 814

Query: 1453 LKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQ--GSPGSRGAPGQYGEKGF 1510
            L G  G +G  G  GI G  G+ G HG PG KG+ G PG    G PG RG+PG  G  G 
Sbjct: 815  LPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGP 873

Query: 1511 PGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRG---VSG 1567
             G PG+PG    + G+ G+ G  G +G  G  G  G P   G  GR G  GL+G   + G
Sbjct: 874  IGPPGSPG----LPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQG 929

Query: 1568 EPGNPGPTGTLGAEG--------------LQGPQGSQGNPGRKGEKGSQGQKGPQGSPGL 1613
            +PG PGPTG  G++G              L G +G +G PG  G  G  G KG QG PG 
Sbjct: 930  QPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD 989

Query: 1614 MGAKGSTGRPGLLGK---KGEPGLPGDLGPVGQTGQRGRQGDSGIPG----YGQMGRKGV 1666
             G  G +G+PGL G    KG PGLPG  G +G  G +G  GD G PG     G  G  GV
Sbjct: 990  PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049

Query: 1667 KGPRGFPGDAGQKGDIGNPGI-----PGGPGPKG---------------------FRGLA 1700
             G  G PG  GQKGD G+PGI     PG PGPKG                       GL 
Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLP 1109

Query: 1701 LTVGLKGEEGSRGLPG---PPGQRGIKGMAGQP 1730
             T G KG+ G  G PG   PPG +GI G  G P
Sbjct: 1110 GTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNP 1142



 Score =  251 bits (641), Expect = 6e-66
 Identities = 157/379 (41%), Positives = 186/379 (49%), Gaps = 46/379 (12%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRG------EDGNPGVRGDTGPQGDKGIAGCPGA 1447
            PG+PG  G  G    KG  G+ G  G  G        G PG++GD G QG  G+ G  G 
Sbjct: 880  PGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGE 939

Query: 1448 WGQKGLKGFSGP-----------KGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSP 1496
             G KG  G  GP           KG  G+ G+ G+ G  G  G+ G+ G+ G PG  G P
Sbjct: 940  KGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQP 999

Query: 1497 GSRGAPGQYGEKGFPGDPG---NPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGS 1553
            G  G PG  G  G PG PG    PG    I G  G  G QG +G  G  GV G P S G 
Sbjct: 1000 GLPGPPGPKGNPGLPGQPGLIGPPGLKGTI-GDMGFPGPQGVEGPPGPSGVPGQPGSPGL 1058

Query: 1554 RGREGQRGLRGVS--GEPGNPGPTGTLGAEGLQGP---QGSQGNPGRKGEKGSQGQKGPQ 1608
             G++G +G  G+S  G PG PGP G  G  G  G    +GS G+PG  G  G+ G KG  
Sbjct: 1059 PGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQP 1118

Query: 1609 GSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVG---------QTGQRGRQGDSGIPG-Y 1658
            G PG  G  G  G  G+ G  G PGLPG+ GPVG           G++G+ G  GIPG  
Sbjct: 1119 GLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPA 1178

Query: 1659 GQMGRKGVKG-----PRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRG 1713
            GQ G  G  G     P G PG +GQKGD G PGIPG PG  G +G     G  G  G +G
Sbjct: 1179 GQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG---EPGFHGFPGVQG 1235

Query: 1714 LPGPPGQRG--IKGMAGQP 1730
             PGPPG  G  ++G  G P
Sbjct: 1236 PPGPPGSPGPALEGPKGNP 1254



 Score =  246 bits (629), Expect = 2e-64
 Identities = 158/404 (39%), Positives = 184/404 (45%), Gaps = 71/404 (17%)

Query: 1395 GIPGPHGTRGLQAMKGSQG-----LKGSRGHRGEDGNPGVRGDTGPQG----------DK 1439
            G PGP G  G +  KG +G     + G  G  G+ G PG+ G  GP G          + 
Sbjct: 394  GPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEP 453

Query: 1440 GIAGCPGAWGQKGLKGFSGPKGGHGDD----------------GIDGLDGEEGCHGFPGI 1483
            G  G PG+ G KGL+G  G KG  GD                 G+ GL G  G  GFPG 
Sbjct: 454  GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQ 513

Query: 1484 KGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKG 1543
            KGEKG  G+ G  G  G PG  G  GFPG  G PG      G KG KGE G  G  G  G
Sbjct: 514  KGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573

Query: 1544 VQGSPSSRGSRGREGQRG------LRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKG 1597
            + G+P   G  G  G +G       +G  G PGNPG  G  G  G  GP G  G PG  G
Sbjct: 574  LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPGPVG 632

Query: 1598 EKGSQGQKGPQGSPGLMGAKGSTGR----------PGLLGKKGEPGLPGDLGPVGQTGQR 1647
            EKG QG  G  G PG+ G KG  G+          PG  G+ G+ GLPGD G  GQ G  
Sbjct: 633  EKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLP 692

Query: 1648 GRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPG--------------------- 1686
            G  G  G PG   +G  G  GP+GFPG  G  G  G PG                     
Sbjct: 693  GIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPG 752

Query: 1687 --IPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAG 1728
              +PG PGP G  G    +G KG+ G  G PGPPG+ G+ G+ G
Sbjct: 753  FALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPG 796



 Score =  246 bits (627), Expect = 3e-64
 Identities = 158/370 (42%), Positives = 179/370 (48%), Gaps = 28/370 (7%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLK 1454
            G+PGP G +G   + G  G  G+ G  G +G PG  G  GP+G+ G A  PG  G  GL 
Sbjct: 707  GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFA-LPGPPGPPGLP 765

Query: 1455 GFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQ--YGEKGFPG 1512
            GF G  G  GD G  G  G  G  G  G+ G KGD G  G PG  G PG    G +G PG
Sbjct: 766  GFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPG 825

Query: 1513 DPGNPGQN-----NNIKGQKGSKGEQGRQ--GRSGQKGVQGSPSSRGSRGREGQRGLRGV 1565
             PG PG       + I G+KG  G  G    G  G++G  G P + G  G  G  GL G 
Sbjct: 826  PPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGK 885

Query: 1566 SGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGL---MGAKGSTGR 1622
            +G  G PG  G +G  G  GP G  G PGR G  G +G  G QG PGL    G KGS G 
Sbjct: 886  AGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGE 945

Query: 1623 PGL--------------LGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGVK 1667
            PGL               G+KGEPGLPG  G  G  G +G  GD G PG  GQ G  G  
Sbjct: 946  PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPP 1005

Query: 1668 GPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMA 1727
            GP+G PG  GQ G IG PG+ G  G  GF G     G  G  G  G PG PG  G KG  
Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065

Query: 1728 GQPVYSQCDL 1737
            G P  S   L
Sbjct: 1066 GDPGISSIGL 1075



 Score =  243 bits (621), Expect = 1e-63
 Identities = 167/468 (35%), Positives = 198/468 (42%), Gaps = 128/468 (27%)

Query: 1391 CKCPGIPGPHGTRGLQAMKGSQGLKG---------SRGHRGEDGNPGVRGDTGPQGDKGI 1441
            C C GI G  G RG   ++G  GL G          RG +G+DG PG  G  G +G  G+
Sbjct: 38   CDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGL 97

Query: 1442 AGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGA 1501
             G PG  G  G+ G  G  G  G  G +G  GE G  G PG  G +G PG  G PG +G 
Sbjct: 98   PGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGE 157

Query: 1502 PGQY------GEKGFPGDPGNPG------------------------------------- 1518
            PG        G KG PG PG PG                                     
Sbjct: 158  PGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGN 217

Query: 1519 QNNNIKGQKGSKGEQGRQGRSG----------------QKGVQGSPSSR----------- 1551
               N +G KG KGEQG QG  G                QKG QG P  R           
Sbjct: 218  MGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP 277

Query: 1552 -----GSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKG 1606
                 G +G +G++G  G  G+PG  G  G  G  GL G  G  G PGR GEKG +G  G
Sbjct: 278  PGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTG 337

Query: 1607 PQGSPGL----------MGAKGSTGRPGLLGKKGE---------PGLP--------GDLG 1639
            P G PGL          +G KG+ G PGL G+KGE         PGLP        G  G
Sbjct: 338  PPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG 397

Query: 1640 PVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIG----------NPGIPG 1689
            P G  G+RG++GD G PG    G  G+ G  G PG  G  G  G           PG PG
Sbjct: 398  PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG 457

Query: 1690 GPGPKGFRGLALTVGLKGEEG-------SRGLPGPPGQRGIKGMAGQP 1730
             PG  G +GL    G+KG++G         G+ GPPGQ G+ G+ G P
Sbjct: 458  PPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPP 505



 Score =  241 bits (614), Expect = 9e-63
 Identities = 152/373 (40%), Positives = 180/373 (48%), Gaps = 41/373 (10%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHR-------GEDGNPGVRGDTGPQGDKGIAGCPG 1446
            PG PGP G+ G + ++G QG+KG +G         G  G PG  G  G  G  G  G PG
Sbjct: 453  PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512

Query: 1447 AWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHG-------FPGIKGEKGDPGSQGSPGSR 1499
              G+KG  G +GPKG  G  G  G  G  G  G       FPG+KG+KG+ GS G+PG  
Sbjct: 513  QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572

Query: 1500 GAPGQYGEKGFPGDPGNPGQNNNI--KGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGRE 1557
            G PG  G+ G PG PG  G+   I  KG++G  G  G  G  G  G  G P   G  G  
Sbjct: 573  GLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPGPV 631

Query: 1558 GQRGLRGVSGEPGNPGPTGTLGAEGLQ----GPQGSQGNPGRKGEKGSQGQKGPQGSPGL 1613
            G++G++GV+G PG PG  G  G  G      G  G  GNPGR G+ G  G  G  G PGL
Sbjct: 632  GEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGL 691

Query: 1614 MGAKGSTGRPGLLG-----------------KKGEPGLPGDLGPVGQTGQRGRQGDSGIP 1656
             G  GS G PG+ G                   G PG PG +G  G  G  G  G  G P
Sbjct: 692  PGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEP 751

Query: 1657 GYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPG 1716
            G+   G  G  G  GF G  G KGD G PG PG PG  G  GL    G KG+ G  G PG
Sbjct: 752  GFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP---GPKGDVGPNGQPG 808

Query: 1717 PPGQRGIKGMAGQ 1729
            P G  G+ G+  Q
Sbjct: 809  PMGPPGLPGIGVQ 821



 Score =  233 bits (595), Expect = 1e-60
 Identities = 156/385 (40%), Positives = 180/385 (46%), Gaps = 57/385 (14%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PGP G RG   + G  G  G  G  G DG PG +G  G  G KG  G PG+ G  GL
Sbjct: 83   PGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGL 142

Query: 1454 KGFSGPKGGHGDDGIDG------LDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGE 1507
            +G  GP G  G  G  G      L G +G  G+PG  G +G PG  G PG  G PG  G 
Sbjct: 143  QGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGL 202

Query: 1508 KGFPGDPGNPGQNNNI----KGQKGSKGEQGRQGRSG----------------QKGVQGS 1547
             G PG PG PG   N+    +G KG KGEQG QG  G                QKG QG 
Sbjct: 203  MGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGL 262

Query: 1548 PSSRG----------------SRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQG 1591
            P  RG                 +G +G++G  G  G+PG  G  G  G  GL G  G  G
Sbjct: 263  PGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPG 322

Query: 1592 NPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQG 1651
             PGR GEKG +G  GP G PGL+  +  TG    +G+KG  GLPG  G  G+ G  G QG
Sbjct: 323  EPGRDGEKGQKGDTGPPGPPGLVIPRPGTGIT--IGEKGNIGLPGLPGEKGERGFPGIQG 380

Query: 1652 DSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGS 1711
              G+PG       G  GP GFPG+ GQKGD G PGI   PGP G             +G 
Sbjct: 381  PPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGI-SIPGPPGL------------DGQ 427

Query: 1712 RGLPGPPGQRGIKGMAGQPVYSQCD 1736
             G PG PG  G  G    P    C+
Sbjct: 428  PGAPGLPGPPGPAGPHIPPSDEICE 452



 Score =  221 bits (562), Expect = 9e-57
 Identities = 162/420 (38%), Positives = 188/420 (44%), Gaps = 88/420 (20%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGV-------------RGDTGPQGDKG 1440
            PG+PGP G  GL   +G +G KG +G +G  G PG              +GD G  GD+G
Sbjct: 209  PGLPGPKGNMGLN-FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRG 267

Query: 1441 IAGCPGAWGQKGLKGFS-GPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSR 1499
              G PG  G  G  G   G KG  G+ G  G  G++G +G PGI G  GDPG  G PG  
Sbjct: 268  PPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRD 327

Query: 1500 GAPGQYGEKGFPGDPG----NPGQ--------NNNIKGQKGSKGEQGRQGRSGQKGVQGS 1547
            G  GQ G+ G PG PG     PG         N  + G  G KGE+G  G  G  G+ G 
Sbjct: 328  GEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP 387

Query: 1548 PSSR-----------GSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQG----- 1591
            P +            G RG++G  G  G+S  PG PG  G  GA GL GP G  G     
Sbjct: 388  PGAAVMGPPGPPGFPGERGQKGDEGPPGIS-IPGPPGLDGQPGAPGLPGPPGPAGPHIPP 446

Query: 1592 -----NPGRKGEKGSQGQKGPQGSPGLMGAKGST----------------GRPGLLGKKG 1630
                  PG  G  GS G KG QG  G+ G KG T                G PGL G  G
Sbjct: 447  SDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPG 506

Query: 1631 EPGLPGDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGVKGPRG----FPGDAGQKGDIGNP 1685
              G PG  G  GQ G  G +G  GIPG  G  G  G KG  G    FPG  G KG++G+P
Sbjct: 507  SLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSP 566

Query: 1686 G---------------IPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQP 1730
            G               +PG PGPKG  G    +  KGE G  G PG PG  G  G  G P
Sbjct: 567  GAPGLPGLPGTPGQDGLPGLPGPKGEPG---GITFKGERGPPGNPGLPGLPGNIGPMGPP 623



 Score =  191 bits (486), Expect = 6e-48
 Identities = 126/332 (37%), Positives = 150/332 (45%), Gaps = 69/332 (20%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKG- 1452
            PG PGP G +G+    G+ GL G  G  G  G+PG  G  G +G  G  G PG  GQKG 
Sbjct: 1124 PGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGE 1183

Query: 1453 -------------LKGFSGPKGGHG------DDGIDGLDGEEGCHGFPGIKGEKGDPGS- 1492
                         L G SG KG  G      + G+ G  GE G HGFPG++G  G PGS 
Sbjct: 1184 PGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSP 1243

Query: 1493 -------QGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQ 1545
                   +G+PG +G PG+ G  G  G PG PG N  IKG+KG+ G+ G  G  G KG Q
Sbjct: 1244 GPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPG-NGGIKGEKGNPGQPGLPGLPGLKGDQ 1302

Query: 1546 GSPSSRGSRGR---------------------------------EGQRGLRGVSGEPGNP 1572
            G P  +G+ GR                                 EG+ GL G  G PG P
Sbjct: 1303 GPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLP 1362

Query: 1573 GPTGT-------LGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGL 1625
            GP+G         G  G+ G  G +G PG +G +G  G  GP G PG  G  G  G  G 
Sbjct: 1363 GPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGR 1422

Query: 1626 LGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPG 1657
             G  G PG PG  G  G  G  G QG  G PG
Sbjct: 1423 KGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1454



 Score =  159 bits (401), Expect = 4e-38
 Identities = 93/211 (44%), Positives = 106/211 (50%), Gaps = 5/211 (2%)

Query: 1516 NPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPT 1575
            +PG   +  G KG KGE+G  G  G  G+ G P   G  G  GQ+G  G+ G PG  G  
Sbjct: 33   SPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIR 92

Query: 1576 GTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLP 1635
            G  G  G  G  G  G PG  G  G QG  G  G+ G  G  GS G PGL G  G PG+P
Sbjct: 93   GPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIP 152

Query: 1636 GDLGPVGQTGQRGRQGDSGIPGY-GQMGRKGVKGPRGFPGDAGQKGD---IGNPGIPGGP 1691
            G  G  G        G  G PGY G  G +G+ GP G PG  G  G    +G PG PG P
Sbjct: 153  GMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLP 212

Query: 1692 GPKGFRGLALTVGLKGEEGSRGLPGPPGQRG 1722
            GPKG  GL    G KGE+G +GL GPPG  G
Sbjct: 213  GPKGNMGLNFQ-GPKGEKGEQGLQGPPGPPG 242



 Score =  155 bits (392), Expect = 5e-37
 Identities = 91/227 (40%), Positives = 116/227 (51%), Gaps = 10/227 (4%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGL 1453
            PG PGP    G +   G QG  G  G  G +G PG+ G+ G +G+KG  G PG  G  GL
Sbjct: 1240 PGSPGP-ALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1298

Query: 1454 KGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGD 1513
            KG  GP G  G+ G  GL+G +G  G PG+ G  G  G  G PGS G  G+ G  G PG 
Sbjct: 1299 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1358

Query: 1514 PGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPG 1573
            PG PG +      KG          +G  G+ G P  +G  G +G +GL G +G PG+PG
Sbjct: 1359 PGLPGPSGQSIIIKGD---------AGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPG 1409

Query: 1574 PTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGST 1620
              G  G +G  G +G  G PG+ G +G  G  GP G  G  G  G++
Sbjct: 1410 RNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTS 1456



 Score =  105 bits (263), Expect = 4e-22
 Identities = 64/141 (45%), Positives = 71/141 (50%), Gaps = 10/141 (7%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDG---NPGVRGDTGPQGD----KGIAGCPGA 1447
            G PG  G  G   MKG  G+ GS G  GE G    PG  G  GP G     KG AG PG 
Sbjct: 1321 GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGI 1380

Query: 1448 WGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKG---EKGDPGSQGSPGSRGAPGQ 1504
             GQ GLKG  GP+G  G  G  G  G+ G +G PG  G    KGDPG  G PG+RG  G 
Sbjct: 1381 PGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGP 1440

Query: 1505 YGEKGFPGDPGNPGQNNNIKG 1525
             G  G  G PG PG ++   G
Sbjct: 1441 PGPDGLQGPPGPPGTSSVAHG 1461



 Score =  105 bits (262), Expect = 6e-22
 Identities = 61/128 (47%), Positives = 71/128 (55%), Gaps = 11/128 (8%)

Query: 1612 GLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRG 1671
            G+ G KG  G PGL   +G PGLPG  GP G  G RG++GD GIPG    G KG++GP G
Sbjct: 42   GIKGEKGERGFPGL---EGHPGLPGFPGPEGPPGPRGQKGDDGIPG--PPGPKGIRGPPG 96

Query: 1672 FPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPG------PPGQRGIKG 1725
             PG  G  G  G PG  G PGP+G  G   T G +G  GS G PG      PPG  G+KG
Sbjct: 97   LPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKG 156

Query: 1726 MAGQPVYS 1733
              G  + S
Sbjct: 157  EPGSIIMS 164



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 41/94 (43%), Positives = 46/94 (48%), Gaps = 10/94 (10%)

Query: 1644 TGQRGRQGDSGIPGY-GQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALT 1702
            +G +G +G+ G PG  G  G  G  GP G PG  GQKGD    GIPG PGPKG RG    
Sbjct: 41   SGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGD---DGIPGPPGPKGIRGPP-- 95

Query: 1703 VGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCD 1736
                G  G  G PG PG  G  G  G      C+
Sbjct: 96   ----GLPGFPGTPGLPGMPGHDGAPGPQGIPGCN 125


>gi|11386161 alpha 2 type IX collagen [Homo sapiens]
          Length = 689

 Score =  267 bits (682), Expect = 1e-70
 Identities = 152/354 (42%), Positives = 190/354 (53%), Gaps = 35/354 (9%)

Query: 1393 CPGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKG 1452
            CP  PG  G  GLQ +KG  G +G  G  G  G PG +GD G  G++GI G PG  G +G
Sbjct: 178  CP--PGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRG 235

Query: 1453 LKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPG 1512
              G +GPKG  G  G  G+ G  G  G PG +G +G PG  G  G  G+PG  G +G  G
Sbjct: 236  YPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITG 295

Query: 1513 DPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNP 1572
              G  G    I G+ G+ G  G +G +GQ G  GSP  +G  G  GQ G +G  G+ G P
Sbjct: 296  PKGATGPPG-INGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEP 354

Query: 1573 GP------TGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPG---LMGAKGSTGRP 1623
            GP      +G  G EG  GP+G  G  G  G+KG QG++GP G PG     G KG  G P
Sbjct: 355  GPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPP 414

Query: 1624 GLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQK---- 1679
            G+ G +G PG+ GD G  G+TG RG+ GD G+ G    G KG KG  G PG  GQ+    
Sbjct: 415  GIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLP--GEKGEKGESGEPGPKGQQGVRG 472

Query: 1680 --------GDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKG 1725
                    GD G PG+ G PGP G RGLA         G+RG+PG PG++G++G
Sbjct: 473  EPGYPGPSGDAGAPGVQGYPGPPGPRGLA---------GNRGVPGQPGRQGVEG 517



 Score =  256 bits (653), Expect = 3e-67
 Identities = 155/390 (39%), Positives = 192/390 (49%), Gaps = 55/390 (14%)

Query: 1396 IPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKG 1455
            I GP G RG     G  G+ GS G  G++G PG  G  GP+G+ G AG  G  G+ G+ G
Sbjct: 25   IRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDG 84

Query: 1456 FSGPKGGHGDDGIDGLDGEEGCHGFPGI-----KGEKGDPGSQGSPGS------RGAPGQ 1504
             +G KG  G  GI G+ G+ G  G PG+      G  G PG  G PG       +G PG 
Sbjct: 85   LTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDPGP 144

Query: 1505 YGEKGFPGDPGNPGQNNNIK----------------GQKGSKGEQGRQGRSGQKGVQGSP 1548
             G  G PG PG PG+   I+                G KG  G QG +G +G++G+ G P
Sbjct: 145  DGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDP 204

Query: 1549 SSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGP---------------------- 1586
              +G  G +G  G  G  G PG PGP G  G  G+ GP                      
Sbjct: 205  GHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPP 264

Query: 1587 --QGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQT 1644
              +G +G PGR GEKG +G  G +G  G+ G KG+TG PG+ GK G PG PG  G  GQ 
Sbjct: 265  GEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQA 324

Query: 1645 GQRGRQGDSGIPGY-GQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTV 1703
            GQ G  G  G+ G  GQ G KG  G +G PG  G  G  G PG  G PGP+G  G    +
Sbjct: 325  GQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIM 384

Query: 1704 GLKGEEGSR---GLPGPPGQRGIKGMAGQP 1730
            G KG++G R   G PGP G++G KG  G P
Sbjct: 385  GQKGDQGERGPVGQPGPQGRQGPKGEQGPP 414



 Score =  247 bits (630), Expect = 1e-64
 Identities = 155/412 (37%), Positives = 187/412 (45%), Gaps = 76/412 (18%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKG-- 1452
            GIPGP G +G++   G  G KG  G  G  G  G  G TGP G++G  G PG  G+KG  
Sbjct: 223  GIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDE 282

Query: 1453 -------LKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQY 1505
                    +G +GPKG  G  GI+G DG  G  G  G  G+ G PGS G  G  G PGQ 
Sbjct: 283  GSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQP 342

Query: 1506 GEKGFPGDPGNPGQNN--------NIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGRE 1557
            G KG PGD G PG             +G+ G +GE G QG  GQKG QG     G  G +
Sbjct: 343  GTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQ 402

Query: 1558 GQRGLRGVSGEPGNPGPTGTLGAEGLQG------PQGSQGNPGRKGEKGSQGQKGPQGSP 1611
            G++G +G  G PG PGP G  G +G +G      P+G  G+PG  G  G +G+KG  G P
Sbjct: 403  GRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEP 462

Query: 1612 GLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGY------------- 1658
            G  G +G  G PG  G  G+ G PG  G  G  G RG  G+ G+PG              
Sbjct: 463  GPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATD 522

Query: 1659 ------------------------------GQMGRKGVKGPRGFPGDAGQKGDIGNPGIP 1688
                                          G MG  G  GP G+PG  G  G  G  G+P
Sbjct: 523  QHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVP 582

Query: 1689 G---------GPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPV 1731
            G           GPKG RG     G  G  G  G+PGPPG  G+ G  GQ +
Sbjct: 583  GIVGAVGQIGNTGPKGKRGEKGDPGEVGR-GHPGMPGPPGIPGLPGRPGQAI 633



 Score =  243 bits (620), Expect = 2e-63
 Identities = 153/371 (41%), Positives = 182/371 (49%), Gaps = 37/371 (9%)

Query: 1394 PGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGA-WGQKG 1452
            PG+PGP G  G     G  GL G  G RG  G+PG  G +GP G  G  G PG   G +G
Sbjct: 110  PGLPGP-GFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEG 168

Query: 1453 LKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPG 1512
               F  P   +   G+ G  G +G  G  G +G  GDPG QG PG +G  G  GE+G PG
Sbjct: 169  SADFLCPT--NCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPG 226

Query: 1513 DPGNPGQNN--NIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPG 1570
             PG  G      + G KG  G  G +G  G  G  G P   G RG  G+ G +G  G PG
Sbjct: 227  PPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPG 286

Query: 1571 NPGPTGTLGAEGLQGP---QGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLG 1627
              GP G  G +G  GP    G  G PG  G KGS GQ G  GSPG  G  G  G+PG  G
Sbjct: 287  IRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKG 346

Query: 1628 ---------------------KKGEPGLPGDLGPVGQTGQRGRQGDSGIPGY----GQMG 1662
                                 K+GEPG  G++GP G  GQ+G QG+ G  G     G+ G
Sbjct: 347  GPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQG 406

Query: 1663 RKGVKGPRGFPGD---AGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPG 1719
             KG +GP G PG     G KGD G+PG  G  G  G  G+A   G KGE+G  G PGP G
Sbjct: 407  PKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKG 466

Query: 1720 QRGIKGMAGQP 1730
            Q+G++G  G P
Sbjct: 467  QQGVRGEPGYP 477



 Score =  229 bits (585), Expect = 2e-59
 Identities = 140/385 (36%), Positives = 184/385 (47%), Gaps = 77/385 (20%)

Query: 1395 GIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQ---K 1451
            G  GP G  G     G+ G+KGS G  G+ G+PG +G  G  G  G  G PG  G+   +
Sbjct: 298  GATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQ 357

Query: 1452 GLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFP 1511
            GL GFSGP G  G+ G  G  G +G  G  G +GE+G  G  G  G +G  G+ G  G P
Sbjct: 358  GLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIP 417

Query: 1512 GDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQ---RGLRGVSGE 1568
            G  G PG    +KG KGS G+ G +G+ G  GV G P  +G +G  G+   +G +GV GE
Sbjct: 418  GPQGLPG----VKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGE 473

Query: 1569 PGNPGPTGTLGAEGLQG------PQGSQGNPGRKGEKGSQGQKGPQ-------------- 1608
            PG PGP+G  GA G+QG      P+G  GN G  G+ G QG +G                
Sbjct: 474  PGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKML 533

Query: 1609 ----------------GSPGLMGAKGSTGRPGLLGKKGE---------PGLPGDLGPVGQ 1643
                            G+ G+MG  G  G PG  GK+G          PG+ G +G +G 
Sbjct: 534  QEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGN 593

Query: 1644 TGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTV 1703
            TG +G++G+ G PG    G  G+ GP G             PG+PG PG           
Sbjct: 594  TGPKGKRGEKGDPGEVGRGHPGMPGPPGI------------PGLPGRPGQ---------- 631

Query: 1704 GLKGEEGSRGLPGPPGQRGIKGMAG 1728
             + G++G RG PG PG+ G  G+ G
Sbjct: 632  AINGKDGDRGSPGAPGEAGRPGLPG 656


>gi|154759255 collagen, type XXVIII precursor [Homo sapiens]
          Length = 1125

 Score =  266 bits (680), Expect = 2e-70
 Identities = 191/564 (33%), Positives = 271/564 (48%), Gaps = 76/564 (13%)

Query: 1394 PGIPGPHGTRGLQAMKG--SQGLKGSRGHRGEDGNPGV-----------RGDTGPQGDKG 1440
            PG PGP G  G+   +G   +G  G +G +G +G  G            +GD GP G +G
Sbjct: 385  PGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQG 444

Query: 1441 IAGCPG--AWGQKGLKGFSGPKGGHGD--DGIDGLDGEEGCHGFPG--------IKGEKG 1488
              G PG  + G++G++G  GP G  G    G+ G  GE G  G  G        ++G KG
Sbjct: 445  PMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPKG 504

Query: 1489 DPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNI----KGQKGSKGEQGRQGRSGQKGV 1544
            +PGS G PG  G PG+ G  G  G+ G PG         KGQ G KG++G++G  G +G 
Sbjct: 505  EPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQ 564

Query: 1545 QGSPSSRGSRGREGQRGLRGVSGE--PGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQ 1602
            +G P   G +G  G  G  G+ G   PG PGP G  G  G+ G +G  G   R G KG Q
Sbjct: 565  RGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIR-GPKGVQ 623

Query: 1603 GQKGPQGSPGLMG--------AKGSTGRPGLLG--------KKGEPGLPGD--------- 1637
            G +GP G+PGL G         +G  G PG +G         KGEPG+ G          
Sbjct: 624  GPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGV 683

Query: 1638 --LGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKG 1695
               GP G TGQ+G  G  G PGYG  G KG +GP+GFPG  G  G     G+PG  G  G
Sbjct: 684  GTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMGH----GLPGQKGEHG 739

Query: 1696 FRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCDLIRFLREHSPCWKEKCPAY 1755
             RG    VG KG++G  G PG PG++G++G  G    ++ ++I+ + E   C   KC   
Sbjct: 740  ERG---DVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLITEICGC-GPKCKET 795

Query: 1756 PTELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNSGTSYLIR 1815
            P ELVF +D+S  V  E+F     II + V  +  R       AR+ +++Y+     +  
Sbjct: 796  PLELVFVIDSSESVGPENF----QIIKNFVKTMADRVALDLATARIGIINYSHKVEKVAN 851

Query: 1816 WSDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYAGANVRRVAVFFSNGQ 1875
               ++ K      +  ++Y    E      A++    ++F+    G  V++VA+  ++GQ
Sbjct: 852  LKQFSSKDDFKLAVDNMQY--LGEGTYTATALQ-AANDMFEDARPG--VKKVALVITDGQ 906

Query: 1876 TASRSSIITATMEFSALDISPTVF 1899
            T SR       +  +A D +  +F
Sbjct: 907  TDSRDKEKLTEVVKNASDTNVEIF 930



 Score =  262 bits (669), Expect = 4e-69
 Identities = 188/510 (36%), Positives = 245/510 (48%), Gaps = 89/510 (17%)

Query: 1303 QVLLIFSDGLQSESNIMLENQSDRLREAGLDALLVVSLNTTAHHEFSSFEFGKRFDYRTH 1362
            +V+L+ +DG+    N  +++ S+  R +G+ + + ++L+T  +        G      T 
Sbjct: 154  KVVLLMTDGIDHPKNPDVQSISEDARISGI-SFITIALSTVVNEAKLRLISGDSSSEPT- 211

Query: 1363 LTIGMRELGKKLSQYLGNIAERTCCCTFCKC----PGIPGPHGTRGLQAMKGSQGLKGS- 1417
            L +    L  K+   L  + E+ C    C+C    PG PGP GT G   +KG +G KG+ 
Sbjct: 212  LLLSDPTLVDKIQDRLDILFEKKCERKICECEKGDPGDPGPPGTHGNPGIKGERGPKGNP 271

Query: 1418 ----RGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDG 1473
                +G  GE G  G+ G  G +G++G  G PG  G KG  G  GPKG  G  GI G  G
Sbjct: 272  GNAQKGEAGERGPGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPG 331

Query: 1474 EEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNI-KGQKGSKGE 1532
            + G  GF G KGE G PG  GSPG+ G  GQ G KG  G  G PG    I  G+ G  G 
Sbjct: 332  DPGPKGFQGNKGEPGPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGP 390

Query: 1533 QGRQGRSGQKGV--QGSPSSRGSRGREGQRGLRG-----VSGEPGNPGPT---------- 1575
            +G +G  G++G+  +G P  +G +G EG  G +G     + GE G+ GP           
Sbjct: 391  RGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG 450

Query: 1576 -GTLGAEGLQGPQG--------SQGNPGRKGEKGS--------------QGQKGPQGSPG 1612
             G+ G +G+QGP G         QG PG KGE G               QG KG  GS G
Sbjct: 451  IGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIG 510

Query: 1613 LMGAKGSTGRPGLLGKKGEPGLPGDLGP--------------VGQTGQRGRQGDSGIPG- 1657
            L G  G  G  G  GKKGE GLPG  GP               G+ G +G QG  G+PG 
Sbjct: 511  LPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGP 570

Query: 1658 YGQMGRKGVKGPRGFPGDA-----GQKGDIGNPGIPG----------GP-GPKGFRGLAL 1701
             G  G  G+ GP G PG +     G KGD G PGIPG          GP G +G RG   
Sbjct: 571  EGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVG 630

Query: 1702 TVGLKGE-----EGSRGLPGPPGQRGIKGM 1726
              GLKG+      G RGLPGPPG  G++G+
Sbjct: 631  APGLKGDGYPGVPGPRGLPGPPGPMGLRGV 660



 Score =  137 bits (346), Expect = 1e-31
 Identities = 80/190 (42%), Positives = 100/190 (52%), Gaps = 6/190 (3%)

Query: 1541 QKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKG 1600
            +KG  G P   G+ G  G +G RG  G PGN    G  G  G  G  G +G+ G +GE G
Sbjct: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPGYKGDKGERGECG 301

Query: 1601 SQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQ 1660
              G KG +GSPG  G KG  G  G+ G  G+PG  G  G  G+ G  G  G  G PG GQ
Sbjct: 302  KPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQ 361

Query: 1661 MGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGF---RGLALTVGLKGEEGSRGLPGP 1717
             G KG +G  G PG  G  G +G PG PG  GP+G    RGL    G  G +G +G  GP
Sbjct: 362  QGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLP-GEGFPGPKGEKGSEGP 419

Query: 1718 PGQRGIKGMA 1727
             G +G++G++
Sbjct: 420  TGPQGLQGLS 429



 Score =  110 bits (275), Expect = 2e-23
 Identities = 66/145 (45%), Positives = 80/145 (55%), Gaps = 9/145 (6%)

Query: 1392 KCPGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQK 1451
            K  G PG  G RGL    G  GL+G  G  G  G PGVRG  GP G +G+ G  G  G  
Sbjct: 635  KGDGYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDT 692

Query: 1452 GLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGD--PGSQGSPGSRGAPGQYGEKG 1509
            G KG  GP G  G  G  G+ GE+G  GFPG KG  G   PG +G  G RG  G+ G+KG
Sbjct: 693  GQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKG 751

Query: 1510 FPGDPGNPGQNNNIKGQKGSKGEQG 1534
              G+PG+PG+    +G +G KG+ G
Sbjct: 752  EIGEPGSPGK----QGLQGPKGDLG 772



 Score = 95.1 bits (235), Expect = 8e-19
 Identities = 58/136 (42%), Positives = 74/136 (54%), Gaps = 23/136 (16%)

Query: 1608 QGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVK 1667
            +G PG  G  G+ G PG+ G++G  G PG+     Q G+ G +G  GIPGY     KG K
Sbjct: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPGN----AQKGEAGERGPGGIPGY-----KGDK 294

Query: 1668 GPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLA---LTVGLKGEEGSRGLPGPP------ 1718
            G RG  G  G KGD G+PG  G  GP+G +G+       G KG +G++G PGPP      
Sbjct: 295  GERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSP 354

Query: 1719 -----GQRGIKGMAGQ 1729
                 GQ+GIKG  GQ
Sbjct: 355  GAPGIGQQGIKGERGQ 370



 Score = 92.8 bits (229), Expect = 4e-18
 Identities = 60/207 (28%), Positives = 105/207 (50%), Gaps = 20/207 (9%)

Query: 611 EVVREICA-EKGCEDMKADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGADKTQIGV 669
           +++ EIC     C++   +++F++DSS S+G ENF+ +K F+K +  ++ +     +IG+
Sbjct: 780 KLITEICGCGPKCKETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGI 839

Query: 670 VQFSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTLTGKALNFVGQYFTHSKGARLGAK 729
           + +S K ++   L ++ ++ +   A+D M  + EGT T  AL      F   + AR G K
Sbjct: 840 INYSHKVEKVANLKQFSSKDDFKLAVDNMQYLGEGTYTATALQAANDMF---EDARPGVK 896

Query: 730 KFLILITDGVAQDDVRDPARILR------GKDVTIFSVGVYNANRSQLEEISGDSSLVF- 782
           K  ++ITDG  Q D RD  ++          +V IF +GV   N    E    + +L+  
Sbjct: 897 KVALVITDG--QTDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIAT 954

Query: 783 ---HVENFDHL----KALERKLIFRVC 802
              HV  FD        L++KL  ++C
Sbjct: 955 DPEHVYQFDDFFTLQDTLKQKLFQKIC 981



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 51/196 (26%), Positives = 91/196 (46%), Gaps = 14/196 (7%)

Query: 796 KLIFRVCALHDCKRITLLDVVFVLDHSGSIKKQYQDHMINLTIHLVKKADVGRDRVQFGA 855
           KLI  +C      + T L++VFV+D S S+  +    + N    +  +  +     + G 
Sbjct: 780 KLITEICGCGPKCKETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGI 839

Query: 856 LKYSDQPNILFYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKHANALFTEEHGSRIKQN 915
           + YS +   +  L  +S++      +   +  G  TYTA AL+ AN +F +      +  
Sbjct: 840 INYSHKVEKVANLKQFSSKDDFKLAVDNMQYLGEGTYTATALQAANDMFED-----ARPG 894

Query: 916 VKQMLIVITDG--ESHDHDQLNDTALELRNKGITIFAVGVGKAN-------QKELEGMAG 966
           VK++ +VITDG  +S D ++L +      +  + IF +GV K N        KE+  +A 
Sbjct: 895 VKKVALVITDGQTDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIAT 954

Query: 967 NKNNTIYVDNFDKLKD 982
           +  +    D+F  L+D
Sbjct: 955 DPEHVYQFDDFFTLQD 970



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 47/190 (24%), Positives = 86/190 (45%), Gaps = 16/190 (8%)

Query: 442 DIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFYITDYSN 501
           ++ F+ID S S+  + F+ IK F+  + +  ++     R+G++ YS   E    +  +S+
Sbjct: 798 ELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGIINYSHKVEKVANLKQFSS 857

Query: 502 DIDLRKAIFNIKQLTGGTYTGKALDYILQIIKNGMKDRMSKVPCYLIVLTDGMSTDR--- 558
             D + A+ N++ L  GTYT  A    LQ   +  +D    V    +V+TDG +  R   
Sbjct: 858 KDDFKLAVDNMQYLGEGTYTATA----LQAANDMFEDARPGVKKVALVITDGQTDSRDKE 913

Query: 559 -VVEPAKRLRAEQITVHAVGIGAAN-------KIELQEIAGKEERV-SFGQNFDALKSIK 609
            + E  K      + +  +G+   N         E+  IA   E V  F   F    ++K
Sbjct: 914 KLTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIATDPEHVYQFDDFFTLQDTLK 973

Query: 610 NEVVREICAE 619
            ++ ++IC +
Sbjct: 974 QKLFQKICED 983



 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 34/153 (22%), Positives = 71/153 (46%), Gaps = 11/153 (7%)

Query: 30  DVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHSEFHLSTFKG 89
           ++VF++DSS+ +GP++F  +K F+  M + + ++    R+ +  YS +     +L  F  
Sbjct: 798 ELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGIINYSHKVEKVANLKQFSS 857

Query: 90  RSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRKQFPPILVVLASAESE-- 147
           +         N Q++G       ALQ A+  +  A      R     + +V+   +++  
Sbjct: 858 KDD-FKLAVDNMQYLGEGTYTATALQAANDMFEDA------RPGVKKVALVITDGQTDSR 910

Query: 148 --DEVEEASKALQKDGVKIISVGVQKASEENLK 178
             +++ E  K      V+I  +GV K ++ N +
Sbjct: 911 DKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFE 943



 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 41/208 (19%), Positives = 96/208 (46%), Gaps = 21/208 (10%)

Query: 231 KDSLADLVFLVDESLGTGG-NLRHLQTFLENITSSMDVKENCMRLGLMSYSNSAKTISFL 289
           K++  +LVF++D S   G  N + ++ F++ +   + +     R+G+++YS+  + ++ L
Sbjct: 793 KETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGIINYSHKVEKVANL 852

Query: 290 KSSTTQSEFQQQIKNLSIQVGKSNTGAAIDQMRRDGFSESYGSRRAQGVPQIAVLVTHRP 349
           K  +++ +F+  + N+   +G+    A   Q   D F ++       GV ++A+++T   
Sbjct: 853 KQFSSKDDFKLAVDNMQ-YLGEGTYTATALQAANDMFEDA-----RPGVKKVALVITDGQ 906

Query: 350 SD----DEVHDAALNLRLEDVNVFALSIQGANNTQLE------EIVSYPPEQTISTLKSY 399
           +D    +++ +   N    +V +F + +   N+   E       +++  PE     +  +
Sbjct: 907 TDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIATDPEH----VYQF 962

Query: 400 ADLETYSTKFLKKLQNEIWSQISTYAEQ 427
            D  T      +KL  +I     +Y  Q
Sbjct: 963 DDFFTLQDTLKQKLFQKICEDFDSYLVQ 990



 Score = 48.9 bits (115), Expect = 6e-05
 Identities = 47/182 (25%), Positives = 83/182 (45%), Gaps = 24/182 (13%)

Query: 2286 QEYYMDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPG 2345
            +E  +++ F+ID+S+ VG + F+ +K F+ ++ D   +A    T+    R+ +++YS   
Sbjct: 793  KETPLELVFVIDSSESVGPENFQIIKNFVKTMAD--RVALDLATA----RIGIINYSH-- 844

Query: 2346 YMPNTEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLR 2405
                     V    +L  ++S    K  + + Q L    +   ALQ   D      P ++
Sbjct: 845  --------KVEKVANLKQFSSKDDFKLAVDNMQYLGEGTYTATALQAANDMFEDARPGVK 896

Query: 2406 KNKVIFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHN------DKELEELAS 2459
              KV  VI+ G+T+S DK+ L  V   A      IFV     K++       KE+  +A+
Sbjct: 897  --KVALVITDGQTDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIAT 954

Query: 2460 HP 2461
             P
Sbjct: 955  DP 956



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 43/162 (26%), Positives = 78/162 (48%), Gaps = 12/162 (7%)

Query: 628 DIMFLVDSSWSIGNENFRKMKIFMKNLLTKI-QIGADKT-----QIGVVQFSDKTKEEFQ 681
           DI+F+VDSS S     F K K F+ +L  KI Q+   ++     ++  +QFS   + +  
Sbjct: 48  DIVFIVDSSESSKIALFDKQKDFVDSLSDKIFQLTPGRSLEYDIKLAALQFSSSVQIDPP 107

Query: 682 LNRYFTQQEISDAIDRMSLINEGTLTGKALNFVGQYFTHSKGARLGAKKFLILITDGV-- 739
            + +   Q     +  M+LI +GT +  A++   +     +  R    K ++L+TDG+  
Sbjct: 108 FSSWKDLQTFKQKVKSMNLIGQGTFSYYAISNATRLL--KREGRKDGVKVVLLMTDGIDH 165

Query: 740 -AQDDVRDPARILRGKDVTIFSVGVYN-ANRSQLEEISGDSS 779
               DV+  +   R   ++  ++ +    N ++L  ISGDSS
Sbjct: 166 PKNPDVQSISEDARISGISFITIALSTVVNEAKLRLISGDSS 207



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 43/210 (20%), Positives = 97/210 (46%), Gaps = 21/210 (10%)

Query: 810  ITLLDVVFVLDHSGSIK-------KQYQDHMINLTIHLVKKADVGRDRVQFGALKYSDQP 862
            I  +D+VF++D S S K       K + D + +    L     +  D ++  AL++S   
Sbjct: 44   ICFIDIVFIVDSSESSKIALFDKQKDFVDSLSDKIFQLTPGRSLEYD-IKLAALQFSSSV 102

Query: 863  NILFYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKHANALFTEEHGSRIKQNVKQMLIV 922
             I    +++ +     + ++     G  T++  A+ +A  L   E     K  VK ++++
Sbjct: 103  QIDPPFSSWKDLQTFKQKVKSMNLIGQGTFSYYAISNATRLLKREGR---KDGVK-VVLL 158

Query: 923  ITDGESH-DHDQLNDTALELRNKGITIFAVGVGK-ANQKELEGMAGNKNN--TIYVDN-- 976
            +TDG  H  +  +   + + R  GI+   + +    N+ +L  ++G+ ++  T+ + +  
Sbjct: 159  MTDGIDHPKNPDVQSISEDARISGISFITIALSTVVNEAKLRLISGDSSSEPTLLLSDPT 218

Query: 977  -FDKLKDVFTLVQERMCTEAPEVCHLQEAD 1005
              DK++D   ++ E+ C    ++C  ++ D
Sbjct: 219  LVDKIQDRLDILFEKKCER--KICECEKGD 246



 Score = 36.2 bits (82), Expect = 0.42
 Identities = 41/169 (24%), Positives = 77/169 (45%), Gaps = 25/169 (14%)

Query: 1958 EDSYMDVVFLIDNSRNIAKDEFKAVKALVSSVIDNFNIASDPLISDSGDRIALLSYSPWE 2017
            +++ +++VF+ID+S ++  + F+ +K  V ++ D   +A D   +    RI +++YS   
Sbjct: 793  KETPLELVFVIDSSESVGPENFQIIKNFVKTMAD--RVALDLATA----RIGIINYSHKV 846

Query: 2018 SSRRKMGTVKTEFDF-ITYDNQLLMKNHIQTSFQQLNGEATIGRALLWTTENLFPET-PY 2075
                 +    ++ DF +  DN             Q  GE T     L    ++F +  P 
Sbjct: 847  EKVANLKQFSSKDDFKLAVDN------------MQYLGEGTYTATALQAANDMFEDARPG 894

Query: 2076 LRKHKVIFVVSAGENYER-KEFVKMMALRAKCQGYVIFVISLGSTRKDD 2123
            ++  KV  V++ G+   R KE +  +   A      IFVI  G  +K+D
Sbjct: 895  VK--KVALVITDGQTDSRDKEKLTEVVKNASDTNVEIFVI--GVVKKND 939


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 98,666,351
Number of Sequences: 37866
Number of extensions: 4973223
Number of successful extensions: 107886
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 216
Number of HSP's successfully gapped in prelim test: 379
Number of HSP's that attempted gapping in prelim test: 15521
Number of HSP's gapped (non-prelim): 7272
length of query: 2526
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2407
effective length of database: 13,741,464
effective search space: 33075703848
effective search space used: 33075703848
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 71 (32.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.