Search of human proteins with 111118972

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein
[Homo sapiens]
         (1650 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...  3529   0.0  
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...  3476   0.0  
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...  3424   0.0  
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...  2452   0.0  
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]     2395   0.0  
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...  2353   0.0  
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...  2246   0.0  
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]  1889   0.0  
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...  1160   0.0  
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...  1157   0.0  
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]    1138   0.0  
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]     1123   0.0  
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]    1103   0.0  
gi|48762934 alpha 2 type I collagen [Homo sapiens]                   1023   0.0  
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   991   0.0  
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   989   0.0  
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   984   0.0  
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]              943   0.0  
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         929   0.0  
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]               912   0.0  
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]    905   0.0  
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...   895   0.0  
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...   894   0.0  
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...   894   0.0  
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...   894   0.0  
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]        885   0.0  
gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]              871   0.0  
gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens]    832   0.0  
gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ...   805   0.0  
gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo s...   805   0.0  

>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score = 3529 bits (9152), Expect = 0.0
 Identities = 1650/1650 (100%), Positives = 1650/1650 (100%)

Query: 1    MERCSRCHRLLLLLPLVLGLSAAPGWAGAPPVDVLRALRFPSLPDGVRRAKGICPADVAY 60
            MERCSRCHRLLLLLPLVLGLSAAPGWAGAPPVDVLRALRFPSLPDGVRRAKGICPADVAY
Sbjct: 1    MERCSRCHRLLLLLPLVLGLSAAPGWAGAPPVDVLRALRFPSLPDGVRRAKGICPADVAY 60

Query: 61   RVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPV 120
            RVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPV
Sbjct: 61   RVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPV 120

Query: 121  RFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSAR 180
            RFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSAR
Sbjct: 121  RFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSAR 180

Query: 181  PVLDTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQ 240
            PVLDTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQ
Sbjct: 181  PVLDTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQ 240

Query: 241  PHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKG 300
            PHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKG
Sbjct: 241  PHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKG 300

Query: 301  EPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPP 360
            EPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPP
Sbjct: 301  EPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPP 360

Query: 361  GTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGS 420
            GTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGS
Sbjct: 361  GTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGS 420

Query: 421  PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGL 480
            PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGL
Sbjct: 421  PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGL 480

Query: 481  PGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV 540
            PGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV
Sbjct: 481  PGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV 540

Query: 541  RGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGS 600
            RGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGS
Sbjct: 541  RGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGS 600

Query: 601  DGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF 660
            DGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF
Sbjct: 601  DGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF 660

Query: 661  KGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR 720
            KGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR
Sbjct: 661  KGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR 720

Query: 721  QGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGG 780
            QGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGG
Sbjct: 721  QGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGG 780

Query: 781  DGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV 840
            DGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV
Sbjct: 781  DGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV 840

Query: 841  VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGF 900
            VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGF
Sbjct: 841  VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGF 900

Query: 901  PGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGE 960
            PGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGE
Sbjct: 901  PGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGE 960

Query: 961  KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 1020
            KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP
Sbjct: 961  KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 1020

Query: 1021 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1080
            PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE
Sbjct: 1021 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1080

Query: 1081 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1140
            KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE
Sbjct: 1081 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1140

Query: 1141 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQ 1200
            PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQ
Sbjct: 1141 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQ 1200

Query: 1201 DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGA 1260
            DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGA
Sbjct: 1201 DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGA 1260

Query: 1261 PGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGA 1320
            PGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGA
Sbjct: 1261 PGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGA 1320

Query: 1321 KGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGP 1380
            KGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGP
Sbjct: 1321 KGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGP 1380

Query: 1381 AGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDE 1440
            AGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDE
Sbjct: 1381 AGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDE 1440

Query: 1441 AIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEY 1500
            AIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEY
Sbjct: 1441 AIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEY 1500

Query: 1501 WVDPNQGCARDAFRVFCNFTAGGETCVTPRDDVTQFSYVDSEGSPVGVVQLTFLRLLSVS 1560
            WVDPNQGCARDAFRVFCNFTAGGETCVTPRDDVTQFSYVDSEGSPVGVVQLTFLRLLSVS
Sbjct: 1501 WVDPNQGCARDAFRVFCNFTAGGETCVTPRDDVTQFSYVDSEGSPVGVVQLTFLRLLSVS 1560

Query: 1561 AHQDVSYPCSGAARDGPLRLRGANEDELSPETSPYVKEFRDGCQTQQGRTVLEVRTPVLE 1620
            AHQDVSYPCSGAARDGPLRLRGANEDELSPETSPYVKEFRDGCQTQQGRTVLEVRTPVLE
Sbjct: 1561 AHQDVSYPCSGAARDGPLRLRGANEDELSPETSPYVKEFRDGCQTQQGRTVLEVRTPVLE 1620

Query: 1621 QLPVLDASFSDLGAPPRRGGVLLGPVCFMG 1650
            QLPVLDASFSDLGAPPRRGGVLLGPVCFMG
Sbjct: 1621 QLPVLDASFSDLGAPPRRGGVLLGPVCFMG 1650


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score = 3476 bits (9012), Expect = 0.0
 Identities = 1629/1650 (98%), Positives = 1629/1650 (98%), Gaps = 21/1650 (1%)

Query: 1    MERCSRCHRLLLLLPLVLGLSAAPGWAGAPPVDVLRALRFPSLPDGVRRAKGICPADVAY 60
            MERCSRCHRLLLLLPLVLGLSAAPGWAGAPPVDVLRALRFPSLPDGVRRAKGICPADVAY
Sbjct: 1    MERCSRCHRLLLLLPLVLGLSAAPGWAGAPPVDVLRALRFPSLPDGVRRAKGICPADVAY 60

Query: 61   RVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPV 120
            RVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPV
Sbjct: 61   RVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPV 120

Query: 121  RFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSAR 180
            RFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSAR
Sbjct: 121  RFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSAR 180

Query: 181  PVLDTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQ 240
            PVLDTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQ
Sbjct: 181  PVLDTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQ 240

Query: 241  PHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKG 300
            PHRAQRSPQQQPSRLHRPQNQEPQSQ                     AAHGPRGLKGEKG
Sbjct: 241  PHRAQRSPQQQPSRLHRPQNQEPQSQ---------------------AAHGPRGLKGEKG 279

Query: 301  EPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPP 360
            EPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPP
Sbjct: 280  EPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPP 339

Query: 361  GTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGS 420
            GTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGS
Sbjct: 340  GTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGS 399

Query: 421  PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGL 480
            PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGL
Sbjct: 400  PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGL 459

Query: 481  PGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV 540
            PGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV
Sbjct: 460  PGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV 519

Query: 541  RGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGS 600
            RGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGS
Sbjct: 520  RGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGS 579

Query: 601  DGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF 660
            DGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF
Sbjct: 580  DGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF 639

Query: 661  KGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR 720
            KGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR
Sbjct: 640  KGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR 699

Query: 721  QGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGG 780
            QGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGG
Sbjct: 700  QGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGG 759

Query: 781  DGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV 840
            DGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV
Sbjct: 760  DGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV 819

Query: 841  VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGF 900
            VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGF
Sbjct: 820  VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGF 879

Query: 901  PGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGE 960
            PGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGE
Sbjct: 880  PGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGE 939

Query: 961  KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 1020
            KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP
Sbjct: 940  KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 999

Query: 1021 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1080
            PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE
Sbjct: 1000 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1059

Query: 1081 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1140
            KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE
Sbjct: 1060 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1119

Query: 1141 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQ 1200
            PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQ
Sbjct: 1120 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQ 1179

Query: 1201 DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGA 1260
            DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGA
Sbjct: 1180 DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGA 1239

Query: 1261 PGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGA 1320
            PGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGA
Sbjct: 1240 PGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGA 1299

Query: 1321 KGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGP 1380
            KGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGP
Sbjct: 1300 KGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGP 1359

Query: 1381 AGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDE 1440
            AGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDE
Sbjct: 1360 AGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDE 1419

Query: 1441 AIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEY 1500
            AIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEY
Sbjct: 1420 AIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEY 1479

Query: 1501 WVDPNQGCARDAFRVFCNFTAGGETCVTPRDDVTQFSYVDSEGSPVGVVQLTFLRLLSVS 1560
            WVDPNQGCARDAFRVFCNFTAGGETCVTPRDDVTQFSYVDSEGSPVGVVQLTFLRLLSVS
Sbjct: 1480 WVDPNQGCARDAFRVFCNFTAGGETCVTPRDDVTQFSYVDSEGSPVGVVQLTFLRLLSVS 1539

Query: 1561 AHQDVSYPCSGAARDGPLRLRGANEDELSPETSPYVKEFRDGCQTQQGRTVLEVRTPVLE 1620
            AHQDVSYPCSGAARDGPLRLRGANEDELSPETSPYVKEFRDGCQTQQGRTVLEVRTPVLE
Sbjct: 1540 AHQDVSYPCSGAARDGPLRLRGANEDELSPETSPYVKEFRDGCQTQQGRTVLEVRTPVLE 1599

Query: 1621 QLPVLDASFSDLGAPPRRGGVLLGPVCFMG 1650
            QLPVLDASFSDLGAPPRRGGVLLGPVCFMG
Sbjct: 1600 QLPVLDASFSDLGAPPRRGGVLLGPVCFMG 1629


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 3424 bits (8877), Expect = 0.0
 Identities = 1628/1736 (93%), Positives = 1633/1736 (94%), Gaps = 86/1736 (4%)

Query: 1    MERCSRCHRLLLLLPLVLGLSAAPGWAGAPPVDVLRALRFPSLPDGVRRAKGICPADVAY 60
            MERCSRCHRLLLLLPLVLGLSAAPGWAGAPPVDVLRALRFPSLPDGVRRAKGICPADVAY
Sbjct: 1    MERCSRCHRLLLLLPLVLGLSAAPGWAGAPPVDVLRALRFPSLPDGVRRAKGICPADVAY 60

Query: 61   RVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPV 120
            RVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPV
Sbjct: 61   RVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPV 120

Query: 121  RFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSAR 180
            RFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSAR
Sbjct: 121  RFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSAR 180

Query: 181  PVLDTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQ 240
            PVLDTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQ
Sbjct: 181  PVLDTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQ 240

Query: 241  PHRAQRS---------------PQQQPSRL----HRPQNQE-------PQSQDPT----- 269
            PHRAQRS               PQ QP+      + P   +       P  QDPT     
Sbjct: 241  PHRAQRSPQQQPSRLHRPQNQEPQSQPTESLYYDYEPPYYDVMTTGTTPDYQDPTPGEEE 300

Query: 270  ---------PGEEEEI---------------------------------------LESSL 281
                     P EEE+                                         E+ L
Sbjct: 301  EILESSLLPPLEEEQTDLQVPPTADRFQAEEYGEGGTDPPEGPYDYTYGYGDDYREETEL 360

Query: 282  LPPLEE-------AAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPG 334
             P L         AAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPG
Sbjct: 361  GPALSAETAHSGAAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPG 420

Query: 335  PVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQ 394
            PVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQ
Sbjct: 421  PVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQ 480

Query: 395  ARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRA 454
            ARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRA
Sbjct: 481  ARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRA 540

Query: 455  GADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPR 514
            GADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPR
Sbjct: 541  GADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPR 600

Query: 515  GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP 574
            GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP
Sbjct: 601  GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP 660

Query: 575  GPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR 634
            GPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR
Sbjct: 661  GPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR 720

Query: 635  GVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPT 694
            GVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPT
Sbjct: 721  GVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPT 780

Query: 695  GDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER 754
            GDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER
Sbjct: 781  GDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER 840

Query: 755  GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKD 814
            GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKD
Sbjct: 841  GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKD 900

Query: 815  GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTA 874
            GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTA
Sbjct: 901  GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTA 960

Query: 875  GKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGER 934
            GKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGER
Sbjct: 961  GKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGER 1020

Query: 935  GAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA 994
            GAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA
Sbjct: 1021 GAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA 1080

Query: 995  GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK 1054
            GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK
Sbjct: 1081 GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK 1140

Query: 1055 GDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPP 1114
            GDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPP
Sbjct: 1141 GDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPP 1200

Query: 1115 GGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD 1174
            GGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD
Sbjct: 1201 GGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD 1260

Query: 1175 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1234
            GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR
Sbjct: 1261 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1320

Query: 1235 GPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRP 1294
            GPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRP
Sbjct: 1321 GPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRP 1380

Query: 1295 GATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSP 1354
            GATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSP
Sbjct: 1381 GATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSP 1440

Query: 1355 GQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEV 1414
            GQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEV
Sbjct: 1441 GQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEV 1500

Query: 1415 IQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRP 1474
            IQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRP
Sbjct: 1501 IQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRP 1560

Query: 1475 TGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGETCVTPRDDVT 1534
            TGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGETCVTPRDDVT
Sbjct: 1561 TGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGETCVTPRDDVT 1620

Query: 1535 QFSYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPCSGAARDGPLRLRGANEDELSPETSP 1594
            QFSYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPCSGAARDGPLRLRGANEDELSPETSP
Sbjct: 1621 QFSYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPCSGAARDGPLRLRGANEDELSPETSP 1680

Query: 1595 YVKEFRDGCQTQQGRTVLEVRTPVLEQLPVLDASFSDLGAPPRRGGVLLGPVCFMG 1650
            YVKEFRDGCQTQQGRTVLEVRTPVLEQLPVLDASFSDLGAPPRRGGVLLGPVCFMG
Sbjct: 1681 YVKEFRDGCQTQQGRTVLEVRTPVLEQLPVLDASFSDLGAPPRRGGVLLGPVCFMG 1736


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 2452 bits (6355), Expect = 0.0
 Identities = 1153/1740 (66%), Positives = 1334/1740 (76%), Gaps = 124/1740 (7%)

Query: 28   GAPPVDVLRALRFPSLPDGVRRAKGICP-------ADVAYRVARPAQLSAPTRQLFPGG- 79
            GA PVDVL+AL F + P+G+ +  G C        +D AYRV++ AQLSAPT+QLFPGG 
Sbjct: 35   GAAPVDVLKALDFHNSPEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGT 94

Query: 80   FPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPVRFLYEDQTGRPQPPSQPVF 139
            FP+DFS+L  V+ + G+Q+ LL++Y+  G++Q+G+E+GR   FL+ED TG+P P   P+F
Sbjct: 95   FPEDFSILFTVKPKKGIQSFLLSIYNEHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLF 154

Query: 140  RGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSARPVLDTHGVIIFGARILDEE 199
            R +++ADGKWHRVA++V+ ++VT+IVDCKK+ T+PL RS R ++DT+G+ +FG RILDEE
Sbjct: 155  RTVNIADGKWHRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEE 214

Query: 200  VFEGDVQELAIVPGVQAAYESCEQKELECEGG-----QRERPQNQQPHRAQRSPQQQPSR 254
            VFEGD+Q+  I    +AAY+ CE    +C+       Q + PQ  + +      +     
Sbjct: 215  VFEGDIQQFLITGDPKAAYDYCEHYSPDCDSSAPKAAQAQEPQIDEANIVDDFQEYNYGT 274

Query: 255  LHRPQNQEPQ----SQDPTPGEE---EEIL-------------------------ESSLL 282
            +   Q + P+    + +P P EE   EE L                         +S LL
Sbjct: 275  MESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLL 334

Query: 283  ----------------------PPLEEAA----------------HGPRGLKGEKGEPAV 304
                                  PP EE                  HG  G KG+KGEPAV
Sbjct: 335  VDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAV 394

Query: 305  LEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSL 364
            +EPGMLVEGPPGP GPAG++GPPG+QG  GP GDPG+RGPPGR GLPG+DG PGPPGT L
Sbjct: 395  VEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTML 454

Query: 365  MLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLK 424
            MLPFR+G G G KGP ++AQEAQAQAILQQAR+ALRGPPGPMG TGRPGP+G PGS G K
Sbjct: 455  MLPFRYG-GDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAK 513

Query: 425  GESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEK 484
            GESGD GPQGPRG QG  GP GK G+RGR GADG RGMPG+PG KGDRGFDGLPGLPG+K
Sbjct: 514  GESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDK 573

Query: 485  GHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMD 544
            GHRG+ G QG PGPPG+DG RG+DGEIGPRGLPGE+GPRGLLGP+G PG PG PG+ G+D
Sbjct: 574  GHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVD 633

Query: 545  GPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPP 604
            GP GPKG++GPQGEPGPPGQQG PG QGLPGPQG IGP GEKGPQGKPGL G+PG+DGPP
Sbjct: 634  GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 693

Query: 605  GHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDI 664
            GHPGKEG  G KG  GP GPQGP+GYPGPRGVKG DG+RGLKG KGEKGEDGFPGFKGD+
Sbjct: 694  GHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDM 753

Query: 665  GVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPK 724
            G+KGDRGEVG  G RGEDGPEGPKGR GPTGDPGP G  GEKGKLGVPGLPGYPGRQGPK
Sbjct: 754  GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 813

Query: 725  GSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPH 784
            GS GFPGFPGA+GEKGARG++GK GPRG+RGPTGPRG RG RG TGK G KGTSGGDGP 
Sbjct: 814  GSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPP 873

Query: 785  GPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ 844
            GPPGERG  GPQGP GFPGPKGPPGPPGKDGLPGHPGQRGE GFQGKTGPPGP GVVGPQ
Sbjct: 874  GPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQ 933

Query: 845  GAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGER 904
            G  GETGP+GERGHPGPPGPPGEQGLPG AGKEG KGDPGP G  GKDGPAGLRGFPGER
Sbjct: 934  GPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGER 993

Query: 905  GLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVP 964
            GLPG  G PGLKG EGP GPPGP GSPGERG+AG+ GPIG PGRPGPQGPPG AGEKG P
Sbjct: 994  GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1053

Query: 965  GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPP 1024
            GEKGP GP GRDGVQGPVGLPGPAGP G  GEDGDKGE+G+PGQKG+KG+KGE+GPPGPP
Sbjct: 1054 GEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP 1113

Query: 1025 GPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET 1084
            G  GPVG PG AG DGEPG RG QG FG KGDEG RGF GPPGPIGLQGLPGP GEKGE 
Sbjct: 1114 GLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGEN 1173

Query: 1085 GDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVK 1144
            GDVGPMGPPGPPGPRGP GPNGADGPQGPPG VG++G  GEKGEPGE+G+PG  GE GV 
Sbjct: 1174 GDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVG 1233

Query: 1145 GPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAK 1204
            GP+GERGEKGE+G PG  GPPG KGP GDDGPKGNPGPVGFPGDPGPPGE GP GQDG  
Sbjct: 1234 GPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVG 1293

Query: 1205 GDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKT 1264
            GD+GEDG+PGQPG PGP+GE GPPGP GKRGP G+ G+EGRQG KGAKG+ GA G PGKT
Sbjct: 1294 GDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKT 1353

Query: 1265 GPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEK 1324
            GPVGP GPAGKPGP+GLRG+PG VG+QG PGA GQ GPPGP+GPPGLPGL+GD G+KGEK
Sbjct: 1354 GPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEK 1413

Query: 1325 GHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPK 1384
            GHPGLIGLIGPPGEQGEKGDRGLPG QGSPG KG+ GIPG +GP+GP GPPGLPGP GPK
Sbjct: 1414 GHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPK 1473

Query: 1385 GAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPT 1444
            G KG+TGP G KG+ G+ GPPG PGPPGEVIQPLPI   KKTRR  +G +   +D  +  
Sbjct: 1474 GNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADADDNILDY 1533

Query: 1445 GGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDP 1504
                    G+EEIFGSL+SL+++IE M+ P GTQ +PARTC+DL+L HP+ PDGEYW+DP
Sbjct: 1534 SD------GMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDGEYWIDP 1587

Query: 1505 NQGCARDAFRVFCNFTAGGETCVTPRDD-----------------VTQF------SYVDS 1541
            NQGC+ D+F+V+CNFT+GGETC+ P                     ++F      SY+D 
Sbjct: 1588 NQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSWPKEKPGSWFSEFKRGKLLSYLDV 1647

Query: 1542 EGSPVGVVQLTFLRLLSVSAHQDVSYPC---------SGAARDGPLRLRGANEDELSPET 1592
            EG+ + +VQ+TFL+LL+ SA Q+ +Y C         S  + D  LR  G+N++E+S + 
Sbjct: 1648 EGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDEEMSYDN 1707

Query: 1593 SPYVKEFRDGCQTQQG--RTVLEVRTPVLEQLPVLDASFSDLGAPPRRGGVLLGPVCFMG 1650
            +P++K   DGC +++G  +TV+E+ TP ++Q+P++D   +D G   ++ G  +GPVCF+G
Sbjct: 1708 NPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVGPVCFLG 1767


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 2395 bits (6207), Expect = 0.0
 Identities = 1166/1828 (63%), Positives = 1328/1828 (72%), Gaps = 198/1828 (10%)

Query: 13   LLP--LVLGLSAAPGWAGAPPVDVLRALRFPSLPDGVRRAKGICPA-------DVAYRVA 63
            LLP  L+L L A P    A P D+L+ L F +LPDG+ +  G C         DVAYRV 
Sbjct: 19   LLPPLLLLLLWAPPPSRAAQPADLLKVLDFHNLPDGITKTTGFCATRRSSKGPDVAYRVT 78

Query: 64   RPAQLSAPTRQLFPGG-FPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPVRF 122
            + AQLSAPT+QL+P   FP+DFS+LT V+ + G QA L+++Y+ QG++Q+GLELGR   F
Sbjct: 79   KDAQLSAPTKQLYPASAFPEDFSILTTVKAKKGSQAFLVSIYNEQGIQQIGLELGRSPVF 138

Query: 123  LYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSARPV 182
            LYED TG+P P   P+FRG++L+DGKWHR+A++V  ++VTLI+DCKK+ T+ L RS  P+
Sbjct: 139  LYEDHTGKPGPEDYPLFRGINLSDGKWHRIALSVHKKNVTLILDCKKKTTKFLDRSDHPM 198

Query: 183  LDTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQPH 242
            +D +G+I+FG RILDEEVFEGD+Q+L  V   +AAY+ CE    +C+    + PQ+Q P+
Sbjct: 199  IDINGIIVFGTRILDEEVFEGDIQQLLFVSDHRAAYDYCEHYSPDCDTAVPDTPQSQDPN 258

Query: 243  ----------------------------RAQRSPQQQPSRLHRPQNQEPQSQDPTP---- 270
                                          + +P ++P    +   + P+   PTP    
Sbjct: 259  PDEYYTEGDGEGETYYYEYPYYEDPEDLGKEPTPSKKPVEAAKETTEVPEELTPTPTEAA 318

Query: 271  ---------GEEEEI---------LESSLLP-PLEEAAHGPRGLKGEKGEPAVLEPGMLV 311
                     G+EE++          E    P P ++  +G    +GE+      +PG   
Sbjct: 319  PMPETSEGAGKEEDVGIGDYDYVPSEDYYTPSPYDDLTYG----EGEENPDQPTDPGAGA 374

Query: 312  E--------------GPPGPEGPAGLIGP----------------------------PGI 329
            E               PP  EG   L G                             PG+
Sbjct: 375  EIPTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDPTSSPSEIGPGM 434

Query: 330  QGNP--------GPVGDPGER----------------GPPGRAGLP-------------- 351
              N         GP G+ G++                GP G AGLP              
Sbjct: 435  PANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGD 494

Query: 352  -------------GSDGAPGPPGTSLMLPFRFGSGG--GDKGPVVAAQEAQAQAILQQAR 396
                         G+DG PGPPGT LMLPFRFG GG  G KGP+V+AQE+QAQAILQQAR
Sbjct: 495  PGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQAR 554

Query: 397  LALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGA 456
            LALRGP GPMG TGRPGP+G PGS GLKGE GD+GPQGPRG QG  GP GK GRRGRAG+
Sbjct: 555  LALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGS 614

Query: 457  DGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGL 516
            DGARGMPG  G KGDRGFDGL GLPGEKGHRGD G  G PGPPG+DGERGDDGE+GPRGL
Sbjct: 615  DGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGL 674

Query: 517  PGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGP 576
            PGE GPRGLLGPKGPPG PGPPGV GMDG  GPKG++GPQGEPGPPGQQG PG QGLPGP
Sbjct: 675  PGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGP 734

Query: 577  QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGV 636
            QGAIGP GEKGP GKPGLPGMPG+DGPPGHPGKEGPPG KG QGP GPQGP+GYPGPRGV
Sbjct: 735  QGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGV 794

Query: 637  KGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGD 696
            KG DGIRGLKG KGEKGEDGFPGFKGD+G+KGDRGE+G PG RGEDGPEGPKGR GP GD
Sbjct: 795  KGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGD 854

Query: 697  PGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGP 756
            PGP G  GEKGKLGVPGLPGYPGRQGPKGS+GFPGFPGA+GEKG RG  GK GPRG+RGP
Sbjct: 855  PGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGP 914

Query: 757  TGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL 816
            TGPRG+RGPRG TGK G KG SGGDGP GPPGERG  GPQGP GFPGPKGPPGPPGKDGL
Sbjct: 915  TGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGL 974

Query: 817  PGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGK 876
            PGHPGQRGE GFQGKTGPPGPPGVVGPQG  GETGPMGERGHPGPPGPPGEQGLPG AGK
Sbjct: 975  PGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGK 1034

Query: 877  EGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGA 936
            EGTKGDPGP G PGKDGP GLRGFPG+RGLPG  G  GLKGNEGP GPPGPAGSPGERG 
Sbjct: 1035 EGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGP 1094

Query: 937  AGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE 996
            AG+ GPIG PGRPGPQGPPG AGEKG PGEKGP GP GRDG+QGPVGLPGPAGP G  GE
Sbjct: 1095 AGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGE 1154

Query: 997  DGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGD 1056
            DGDKGE+G+PGQKG+KG+KGE GPPGP GP GP+GQPG +GADGEPG RG QG FG KGD
Sbjct: 1155 DGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGD 1214

Query: 1057 EGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGG 1116
            EG RGF GPPGP+GLQGLPGP GEKGETGDVG MGPPGPPGPRGP+G  GADGPQGPPGG
Sbjct: 1215 EGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGG 1274

Query: 1117 VGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGP 1176
            +GN G  GEKGEPGE+G PG+ GE G  GP+GERGEKGESG  G  GPPGPKGP GDDGP
Sbjct: 1275 IGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGP 1334

Query: 1177 KGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGP 1236
            KG+PGPVGFPGDPGPPGE GP GQDG  GD+G+DGEPGQ GSPGPTGE GP GP GKRGP
Sbjct: 1335 KGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGP 1394

Query: 1237 AGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGA 1296
             G  G EGRQG KGAKG+ G  G PGKTGP+GP G  GKPGPDGLRG+PG VG+QG PG+
Sbjct: 1395 PGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGS 1454

Query: 1297 TGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQ 1356
             G  GPPGP+GPPGLPGL+GD+G KGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGS G 
Sbjct: 1455 PGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGP 1514

Query: 1357 KGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQ 1416
            KGE GI G SGPIGP GPPGLPGP GPKGAKG++GP GPKGE G  GPPG PGPPGEVIQ
Sbjct: 1515 KGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQ 1574

Query: 1417 PLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTG 1476
            PLPIQ   +TRR++D S+L+ +              G+EEIFGSL+SL+ EIEQM+RP G
Sbjct: 1575 PLPIQ-ASRTRRNIDASQLLDDGNG---ENYVDYADGMEEIFGSLNSLKLEIEQMKRPLG 1630

Query: 1477 TQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGETCVTPRDD---- 1532
            TQ +PARTC+DL+LCHP+ PDGEYWVDPNQGC+RD+F+V+CNFTAGG TCV P       
Sbjct: 1631 TQQNPARTCKDLQLCHPDFPDGEYWVDPNQGCSRDSFKVYCNFTAGGSTCVFPDKKSEGA 1690

Query: 1533 -VTQF------------------SYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPC---- 1569
             +T +                  SYVD+EG+PVGVVQ+TFLRLLS SAHQ+V+Y C    
Sbjct: 1691 RITSWPKENPGSWFSEFKRGKLLSYVDAEGNPVGVVQMTFLRLLSASAHQNVTYHCYQSV 1750

Query: 1570 -----SGAARDGPLRLRGANEDELSPETSPYVKEFRDGCQTQQG--RTVLEVRTPVLEQL 1622
                 +  + D  LR  G+N++E+S + +PY++   DGC T++G  +TVLE+ TP +EQ+
Sbjct: 1751 AWQDAATGSYDKALRFLGSNDEEMSYDNNPYIRALVDGCATKKGYQKTVLEIDTPKVEQV 1810

Query: 1623 PVLDASFSDLGAPPRRGGVLLGPVCFMG 1650
            P++D  F+D G   ++ G  +GP CFMG
Sbjct: 1811 PIVDIMFNDFGEASQKFGFEVGPACFMG 1838


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 2353 bits (6098), Expect = 0.0
 Identities = 1124/1780 (63%), Positives = 1311/1780 (73%), Gaps = 165/1780 (9%)

Query: 28   GAPPVDVLRALRFPSLPDGVRRAKGICP-------ADVAYRVARPAQLSAPTRQLFPGG- 79
            GA PVDVL+AL F + P+G+ +  G C        +D AYRV++ AQLSAPT+QLFPGG 
Sbjct: 35   GAAPVDVLKALDFHNSPEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGT 94

Query: 80   FPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPVRFLYEDQTGRPQPPSQPVF 139
            FP+DFS+L  V+ + G+Q+ LL++Y+  G++Q+G+E+GR   FL+ED TG+P P   P+F
Sbjct: 95   FPEDFSILFTVKPKKGIQSFLLSIYNEHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLF 154

Query: 140  RGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSARPVLDTHGVIIFGARILDEE 199
            R +++ADGKWHRVA++V+ ++VT+IVDCKK+ T+PL RS R ++DT+G+ +FG RILDEE
Sbjct: 155  RTVNIADGKWHRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEE 214

Query: 200  VFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQPHRAQRSPQ---QQPSRLH 256
            VFEGD+Q+  I    +AAY+ CE    +C+    +  Q Q+P   + +P+   +      
Sbjct: 215  VFEGDIQQFLITGDPKAAYDYCEHYSPDCDSSAPKAAQAQEPQIDEYAPEDIIEYDYEYG 274

Query: 257  RPQNQEPQSQDPTPGEEEEIL---ESSLLPPLEEAAHG---------PRGLKG------- 297
              + +E +S    P   EE +   E++++   +E  +G         PR + G       
Sbjct: 275  EAEYKEAESVTEGPTVTEETIAQTEANIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPV 334

Query: 298  --------------------------EKGEPAVLEPGMLVEG------------------ 313
                                      E  E    +  +LV+G                  
Sbjct: 335  EEIFTEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPT 394

Query: 314  -PPGPEGPAGL----------IGPPGIQGNPGPVGDPG-------ERGPPGRAG------ 349
             PP  E   G+          I   G  G  G  G+P          GPPG AG      
Sbjct: 395  SPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMG 454

Query: 350  ------------------------LPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQE 385
                                    LPG+DG PGPPGT LMLPFR+G G G KGP ++AQE
Sbjct: 455  PPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYG-GDGSKGPTISAQE 513

Query: 386  AQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPP 445
            AQAQAILQQAR+ALRGPPGPMG TGRPGP+G PGS G KGESGD GPQGPRG QG  GP 
Sbjct: 514  AQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPT 573

Query: 446  GKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGER 505
            GK G+RGR GADG RGMPG+PG KGDRGFDGLPGLPG+KGHRG+ G QG PGPPG+DG R
Sbjct: 574  GKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMR 633

Query: 506  GDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQ 565
            G+DGEIGPRGLPGE+GPRGLLGP+G PG PG PG+ G+DGP GPKG++GPQGEPGPPGQQ
Sbjct: 634  GEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQ 693

Query: 566  GTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQ 625
            G PG QGLPGPQG IGP GEKGPQGKPGL G+PG+DGPPGHPGKEG  G KG  GP GPQ
Sbjct: 694  GNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQ 753

Query: 626  GPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPE 685
            GP+GYPGPRGVKG DG+RGLKG KGEKGEDGFPGFKGD+G+KGDRGEVG  G RGEDGPE
Sbjct: 754  GPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPE 813

Query: 686  GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLS 745
            GPKGR GPTGDPGP G  GEKGKLGVPGLPGYPGRQGPKGS GFPGFPGA+GEKGARG++
Sbjct: 814  GPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA 873

Query: 746  GKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK 805
            GK GPRG+RGPTGPRG RG RG TGK G KGTSGGDGP GPPGERG  GPQGP GFPGPK
Sbjct: 874  GKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPK 933

Query: 806  GPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPP 865
            GPPGPPGKDGLPGHPGQRGE GFQGKTGPPGP GVVGPQG  GETGP+GERGHPGPPGPP
Sbjct: 934  GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 993

Query: 866  GEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPP 925
            GEQGLPG AGKEG KGDPGP G  GKDGPAGLRGFPGERGLPG  G PGLKG EGP GPP
Sbjct: 994  GEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPP 1053

Query: 926  GPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLP 985
            GP GSPGERG+AG+ GPIG PGRPGPQGPPG AGEKG PGEKGP GP GRDGVQGPVGLP
Sbjct: 1054 GPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLP 1113

Query: 986  GPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGAR 1045
            GPAGP G  GEDGDKGE+G+PGQKG+KG+KGE+GPPGPPG  GPVG PG AG DGEPG R
Sbjct: 1114 GPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPR 1173

Query: 1046 GPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPN 1105
            G QG FG KGDEG RGF GPPGPIGLQGLPGP GEKGE GDVGPMGPPGPPGPRGP GPN
Sbjct: 1174 GQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPN 1233

Query: 1106 GADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1165
            GADGPQGPPG VG++G  GEKGEPGE+G+PG  GE GV GP+GERGEKGE+G PG  GPP
Sbjct: 1234 GADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP 1293

Query: 1166 GPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGEN 1225
            G KGP GDDGPKGNPGPVGFPGDPGPPGE GP GQDG  GD+GEDG+PGQPG PGP+GE 
Sbjct: 1294 GAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEA 1353

Query: 1226 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLP 1285
            GPPGP GKRGP G+ G+EGRQG KGAKG+ GA G PGKTGPVGP GPAGKPGP+GLRG+P
Sbjct: 1354 GPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIP 1413

Query: 1286 GSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDR 1345
            G VG+QG PGA GQ GPPGP+GPPGLPGL+GD G+KGEKGHPGLIGLIGPPGEQGEKGDR
Sbjct: 1414 GPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDR 1473

Query: 1346 GLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPP 1405
            GLPG QGSPG KG+ GIPG +GP+GP GPPGLPGP GPKG KG+TGP G KG+ G+ GPP
Sbjct: 1474 GLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPP 1533

Query: 1406 GHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLR 1465
            G PGPPGEVIQPLPI   KKTRR  +G +   +D  +          G+EEIFGSL+SL+
Sbjct: 1534 GSPGPPGEVIQPLPILSSKKTRRHTEGMQADADDNILDYS------DGMEEIFGSLNSLK 1587

Query: 1466 EEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGET 1525
            ++IE M+ P GTQ +PARTC+DL+L HP+ PDGEYW+DPNQGC+ D+F+V+CNFT+GGET
Sbjct: 1588 QDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGET 1647

Query: 1526 CVTPRDDVTQ------------------------FSYVDSEGSPVGVVQLTFLRLLSVSA 1561
            C+ P D  ++                         SY+D EG+ + +VQ+TFL+LL+ SA
Sbjct: 1648 CIYP-DKKSEGVRISSWPKEKPGSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTASA 1706

Query: 1562 HQDVSYPC---------SGAARDGPLRLRGANEDELSPETSPYVKEFRDGCQTQQG--RT 1610
             Q+ +Y C         S  + D  LR  G+N++E+S + +P++K   DGC +++G  +T
Sbjct: 1707 RQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDEEMSYDNNPFIKTLYDGCASRKGYEKT 1766

Query: 1611 VLEVRTPVLEQLPVLDASFSDLGAPPRRGGVLLGPVCFMG 1650
            V+E+ TP ++Q+P++D   +D G   ++ G  +GPVCF+G
Sbjct: 1767 VIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVGPVCFLG 1806


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 2246 bits (5819), Expect = 0.0
 Identities = 1032/1424 (72%), Positives = 1161/1424 (81%), Gaps = 49/1424 (3%)

Query: 263  PQSQDPTPG--EEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGP 320
            P +++  PG   E +I E+S+        HG  G KG+KGEPAV+EPGMLVEGPPGP GP
Sbjct: 408  PPNEEFGPGVPAETDITETSI------NGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGP 461

Query: 321  AGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPV 380
            AG++GPPG+QG  GP GDPG+RGPPGR GLPG+DG PGPPGT LMLPFR+G G G KGP 
Sbjct: 462  AGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYG-GDGSKGPT 520

Query: 381  VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 440
            ++AQEAQAQAILQQAR+ALRGPPGPMG TGRPGP+G PGS G KGESGD GPQGPRG QG
Sbjct: 521  ISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQG 580

Query: 441  LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 500
              GP GK G+RGR GADG RGMPG+PG KGDRGFDGLPGLPG+KGHRG+ G QG PGPPG
Sbjct: 581  PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 640

Query: 501  EDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG 560
            +DG RG+DGEIGPRGLPGE+GPRGLLGP+G PG PG PG+ G+DGP GPKG++GPQGEPG
Sbjct: 641  DDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPG 700

Query: 561  PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQG 620
            PPGQQG PG QGLPGPQG IGP GEKGPQGKPGL G+PG+DGPPGHPGKEG  G KG  G
Sbjct: 701  PPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALG 760

Query: 621  PSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRG 680
            P GPQGP+GYPGPRGVKG DG+RGLKG KGEKGEDGFPGFKGD+G+KGDRGEVG  G RG
Sbjct: 761  PPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRG 820

Query: 681  EDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKG 740
            EDGPEGPKGR GPTGDPGP G  GEKGKLGVPGLPGYPGRQGPKGS GFPGFPGA+GEKG
Sbjct: 821  EDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKG 880

Query: 741  ARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNG 800
            ARG++GK GPRG+RGPTGPRG RG RG TGK G KGTSGGDGP GPPGERG  GPQGP G
Sbjct: 881  ARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVG 940

Query: 801  FPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPG 860
            FPGPKGPPGPPGKDGLPGHPGQRGE GFQGKTGPPGP GVVGPQG  GETGP+GERGHPG
Sbjct: 941  FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPG 1000

Query: 861  PPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEG 920
            PPGPPGEQGLPG AGKEG KGDPGP G  GKDGPAGLRGFPGERGLPG  G PGLKG EG
Sbjct: 1001 PPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEG 1060

Query: 921  PSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQG 980
            P GPPGP GSPGERG+AG+ GPIG PGRPGPQGPPG AGEKG PGEKGP GP GRDGVQG
Sbjct: 1061 PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQG 1120

Query: 981  PVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADG 1040
            PVGLPGPAGP G  GEDGDKGE+G+PGQKG+KG+KGE+GPPGPPG  GPVG PG AG DG
Sbjct: 1121 PVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1180

Query: 1041 EPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG 1100
            EPG RG QG FG KGDEG RGF GPPGPIGLQGLPGP GEKGE GDVGPMGPPGPPGPRG
Sbjct: 1181 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRG 1240

Query: 1101 PAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPG 1160
            P GPNGADGPQGPPG VG++G  GEKGEPGE+G+PG  GE GV GP+GERGEKGE+G PG
Sbjct: 1241 PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPG 1300

Query: 1161 EPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPG 1220
              GPPG KGP GDDGPKGNPGPVGFPGDPGPPGE GP GQDG  GD+GEDG+PGQPG PG
Sbjct: 1301 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1360

Query: 1221 PTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDG 1280
            P+GE GPPGP GKRGP G+ G+EGRQG KGAKG+ GA G PGKTGPVGP GPAGKPGP+G
Sbjct: 1361 PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEG 1420

Query: 1281 LRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQG 1340
            LRG+PG VG+QG PGA GQ GPPGP+GPPGLPGL+GD G+KGEKGHPGLIGLIGPPGEQG
Sbjct: 1421 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG 1480

Query: 1341 EKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKG 1400
            EKGDRGLPG QGSPG KG+ GIPG +GP+GP GPPGLPGP GPKG KG+TGP G KG+ G
Sbjct: 1481 EKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSG 1540

Query: 1401 VQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGS 1460
            + GPPG PGPPGEVIQPLPI   KKTRR  +G +   +D  +          G+EEIFGS
Sbjct: 1541 LPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADADDNILDYSD------GMEEIFGS 1594

Query: 1461 LDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFT 1520
            L+SL+++IE M+ P GTQ +PARTC+DL+L HP+ PDGEYW+DPNQGC+ D+F+V+CNFT
Sbjct: 1595 LNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFT 1654

Query: 1521 AGGETCVTPRDD-----------------VTQF------SYVDSEGSPVGVVQLTFLRLL 1557
            +GGETC+ P                     ++F      SY+D EG+ + +VQ+TFL+LL
Sbjct: 1655 SGGETCIYPDKKSEGVRISSWPKEKPGSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKLL 1714

Query: 1558 SVSAHQDVSYPC---------SGAARDGPLRLRGANEDELSPETSPYVKEFRDGCQTQQG 1608
            + SA Q+ +Y C         S  + D  LR  G+N++E+S + +P++K   DGC +++G
Sbjct: 1715 TASARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDEEMSYDNNPFIKTLYDGCASRKG 1774

Query: 1609 --RTVLEVRTPVLEQLPVLDASFSDLGAPPRRGGVLLGPVCFMG 1650
              +TV+E+ TP ++Q+P++D   +D G   ++ G  +GPVCF+G
Sbjct: 1775 YEKTVIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVGPVCFLG 1818


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score = 1889 bits (4894), Expect = 0.0
 Identities = 955/1758 (54%), Positives = 1146/1758 (65%), Gaps = 156/1758 (8%)

Query: 16   LVLGLSAAPGWAGAPPVDVLRALRFPSLPDGVRRAKGICP-----ADVAYRVARPAQLSA 70
            L+  L   PG   A PVDVL+AL       GV    G CP      D A+R+ + + L  
Sbjct: 17   LLAALQLLPG-TQADPVDVLKALGVQGGQAGVPEGPGFCPQRTPEGDRAFRIGQASTLGI 75

Query: 71   PTRQLFPGG-FPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPVRFLYEDQTG 129
            PT +LFP G FP++FSLL  +R +P  Q+ LL++Y  +G RQLGL LG  +  L +    
Sbjct: 76   PTWELFPEGHFPENFSLLITLRGQPANQSVLLSIYDERGARQLGLALGPALGLLGD---- 131

Query: 130  RPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSARPVLDTHGVI 189
                P +P+ + ++L DG+WHRVAV++ G+ VTL+ DC+ +   P+       +   G+ 
Sbjct: 132  ----PFRPLPQQVNLTDGRWHRVAVSIDGEMVTLVADCEAQP--PVLGHGPRFISIAGLT 185

Query: 190  IFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEG-------GQRERPQNQQPH 242
            + G + L E+ FEGD+QEL I P  QAA+++CE+   +C+          +  P+  +P 
Sbjct: 186  VLGTQDLGEKTFEGDIQELLISPDPQAAFQACERYLPDCDNLAPAATVAPQGEPETPRPR 245

Query: 243  RAQRSPQQQPSRLH----RPQNQE-------------------PQSQDPTPG-------- 271
            R  +   ++  R      R +N+E                   P+++ P P         
Sbjct: 246  RKGKGKGRKKGRGRKGKGRKKNKEIWTSSPPPDSAENQTSTDIPKTETPAPNLPPTPTPL 305

Query: 272  ------------------------------------EEEEILESSLLPPLEEAAHGPR-- 293
                                                E+EE  +S++ P    A +  R  
Sbjct: 306  VVTSTVTTGLNATILERSLDPDSGTELGTLETKAAREDEEGDDSTMGPDFRAAEYPSRTQ 365

Query: 294  -------GLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPG 346
                   G KG KGEPAV+E G   EGPPG  GP G++GP G  G PG  GDPG  GP G
Sbjct: 366  FQIFPGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAG 425

Query: 347  RAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPM 406
              G+PG DG  GPPGT +M+PF+F +GG  KGP V+ Q+AQAQA+LQQ +L+++GPPGP+
Sbjct: 426  LPGIPGIDGIRGPPGTVIMMPFQF-AGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPV 484

Query: 407  GYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDP 466
            G TGRPGP+G PG PGLKGE G  GPQGPRG QG  GPPG+ G+ GR GADGARG+PGD 
Sbjct: 485  GLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDT 544

Query: 467  GVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLL 526
            G KGDRGFDGLPGLPGEKG RGD G  G PGPPGEDGERG +G  GP G  GE GPRGLL
Sbjct: 545  GPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLL 604

Query: 527  GPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEK 586
            GP+G PG  G PGV G+DG  G KG++GP GEPGPPGQQG  G+QGLPGPQG IG  GEK
Sbjct: 605  GPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEK 664

Query: 587  GPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLK 646
            GP G PG+PG+PGSDGP GHPG EGP G KG QGP G  GP GYPGPRGVKG  G RGL+
Sbjct: 665  GPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQ 724

Query: 647  GHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEK 706
            G KGEKGEDGFPGFKGD+G+KGD+G+ G PG RGEDGPEGPKG+ G  G+ GPPG  GEK
Sbjct: 725  GEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEK 784

Query: 707  GKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPR 766
            GKLGVPGLPGYPGR GPKGS+GFPG  G  GEKG  G +G+ G  GERGP G RG+RG  
Sbjct: 785  GKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQP 844

Query: 767  GATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEV 826
            GATG+ G KG  G DG  G PGE+GLPG QGP GFPGPKGPPG  GKDG PGHPGQRGE+
Sbjct: 845  GATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGEL 904

Query: 827  GFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPP 886
            GFQG+TGPPGP GV+GPQG  GE GP+GERG PGPPGPPGEQGLPG  G+EG KG+ GPP
Sbjct: 905  GFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPP 964

Query: 887  GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPP 946
            G  GK+GPAGLRGFPG +G PG  G  GLKG++GP GP G  GSPGERG  G  G IG P
Sbjct: 965  GPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLP 1024

Query: 947  GRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP 1006
            G+ G +GP G AG+KG  GE+GP GPTG+DG+ GP+G  GP G  G +GE+GDKG+VG P
Sbjct: 1025 GQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAP 1084

Query: 1007 GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP 1066
            G KG+KG+KG+ GPPG PG  GP G PG  GADG  G RGP G FG KGD+G RGF G  
Sbjct: 1085 GHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVI 1144

Query: 1067 GPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEK 1126
            GP GLQGLPGP GEKGE GDVG MGP G PGPRGP GP G++G  G PGGVG  G  GEK
Sbjct: 1145 GPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEK 1204

Query: 1127 GEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFP 1186
            GE G++G PG  G PG+ GP+G+ GEKG+SG  G  GPPG KGP G+DG KG+ GP G P
Sbjct: 1205 GERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLP 1264

Query: 1187 GDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQ 1246
            GD GPPG+ G  G DG+ G++G+ G+ G PG PG +GE G PGP GKRGP+G  G EGR+
Sbjct: 1265 GDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGRE 1324

Query: 1247 GGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPV 1306
            G KGAKG+PG  G PG+TGP+G  GP G+ GP+GLRG+PG VG+ G  GA GQ GPPGP+
Sbjct: 1325 GEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPL 1384

Query: 1307 GPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGAS 1366
            GP GLPGL+GD G KGEKGH GLIGLIGPPGE GEKGD+GLPG QG PG KG+ G PG  
Sbjct: 1385 GPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPI 1444

Query: 1367 GPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKT 1426
            G +G  GPPG+ GP G KG+KG+ G  GP+G+ G  GPPG PG P E             
Sbjct: 1445 GSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAPAE------------- 1491

Query: 1427 RRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQ 1486
               + G R  +    +P    P   GGLEE+  SL SL  E+EQ+RRP GT + P   C 
Sbjct: 1492 ---LHGLRRRRRFVPVP---LPVVEGGLEEVLASLTSLSLELEQLRRPPGTAERPGLVCH 1545

Query: 1487 DLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGETCVTPRDDV------------- 1533
            +L   HP LPDGEYW+DPNQGCARD+FRVFCNFTAGGETC+ P                 
Sbjct: 1546 ELHRNHPHLPDGEYWIDPNQGCARDSFRVFCNFTAGGETCLYPDKKFEIVKLASWSKEKP 1605

Query: 1534 ----------TQFSYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPCSGAAR--------- 1574
                       +FSYVD++GSPV VVQL FL+LLS +A Q+ +Y C  AA          
Sbjct: 1606 GGWYSTFRRGKKFSYVDADGSPVNVVQLNFLKLLSATARQNFTYSCQNAAAWLDEATGDY 1665

Query: 1575 DGPLRLRGANEDELS--PETSPYVKEFRDGCQTQQG--RTVLEVRTPVLEQLPVLDASFS 1630
                R  G N +ELS    T+  V   +DGC+ ++G  +T+ E  +     LP+ D + +
Sbjct: 1666 SHSARFLGTNGEELSFNQTTAATVSVPQDGCRLRKGQTKTLFEFSSSRAGFLPLWDVAAT 1725

Query: 1631 DLGAPPRRGGVLLGPVCF 1648
            D G   ++ G  LGPVCF
Sbjct: 1726 DFGQTNQKFGFELGPVCF 1743


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score = 1160 bits (3000), Expect = 0.0
 Identities = 656/1424 (46%), Positives = 770/1424 (54%), Gaps = 95/1424 (6%)

Query: 289  AHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA 348
            A G  G KG+KGEP  ++  +  +GPPGP+GPAG  GP G +G+ G  G PG RG  G  
Sbjct: 96   ASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 155

Query: 349  GLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQA---QAILQQARLALRGPPGP 405
            G PG+ G PGPPG     P   G GG     +    + +A   Q  + Q  +   GP GP
Sbjct: 156  GTPGNPGPPGPPGP----PGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGP 211

Query: 406  MGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGD 465
             G  G PGP G  G+PG  GE G  GP GPRGP G   PPGK G  G AG  G  G  G 
Sbjct: 212  PGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPG---PPGKPGDDGEAGKPGKAGERGP 268

Query: 466  PGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGL 525
            PG +G RGF G PGLPG KGHRG  G  G  G  G  G +G+ G  G  G PG  GPRGL
Sbjct: 269  PGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGL 328

Query: 526  LGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGE 585
             G +G  G  G  G RG DG  GP G  GP G  G PG  G PG +G  GP GA GP G 
Sbjct: 329  PGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGA 388

Query: 586  KGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGL 645
            +GP+G+PG PG PG  G  G+PG +G PG KG+ G  G  G  G+PGPRG  G  G  G 
Sbjct: 389  QGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGP 448

Query: 646  KGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGE 705
             G KG+ GE G  GFKG+ G KG+ G  G  G+ G  G EG +G  G  G  GP G  GE
Sbjct: 449  LGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGE 508

Query: 706  KGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG---ERGPTGPRGQ 762
            +G  G  G PG  G  GPKG+ G  G  G +G KGA G  G+ G  G    RG TG  G 
Sbjct: 509  RGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGD 568

Query: 763  RGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK---DGLPGH 819
             GP+G  G SGA G  G  GP GP G RG PG  G   FPGPKG  G PGK    GLPG 
Sbjct: 569  AGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMG---FPGPKGANGEPGKAGEKGLPGA 625

Query: 820  PGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG---PMGERGHPGPPGPPGEQGLPGTAGK 876
            PG RG  G  G+TG  GPPG  GP G  GE G   P G +G PGPPGPPGE       GK
Sbjct: 626  PGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGE------GGK 679

Query: 877  EGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGA 936
             G +G PG  GAPG  GP G RGFPGERG PG  G  G +G  G  G  GP G+ G  G 
Sbjct: 680  PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGP 739

Query: 937  AGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE 996
             G+ GP G  G PG +G  G AG KG  G+ G  GP G  G  G  GL GP GPPG AG 
Sbjct: 740  PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 799

Query: 997  DGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGD 1056
            +G+KGEVG PG  G+ G +G  G  G  GP GP G  G  GADG+PGA+G QG  G KGD
Sbjct: 800  NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGD 859

Query: 1057 EGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGG 1116
             G  G  GP G  G QG  G +G KG  G  GP G  G PG  G  GP G++G  GPPG 
Sbjct: 860  AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP 919

Query: 1117 VGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG---ERGEKGESGQPGEPGPPGPKGPTGD 1173
             G  G  G KG  G+SG PG  GEPG++GP G   E+GE G+ G  G  GPPGP+G  G 
Sbjct: 920  PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ 979

Query: 1174 DGPKGNPGPVG---FPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP 1230
             G  G PG  G   FPG PGP GE G +G  GA GDRG  G  G PG  GP GE   PG 
Sbjct: 980  RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGE---PGR 1036

Query: 1231 LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQ 1290
             G  G  G PG +G  G KG +G+ GA+GAPG  GP G  GPAG  G  G RG  G+ G 
Sbjct: 1037 EGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1096

Query: 1291 QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP 1350
             G  G  G  G  GP GP G  G  G+ G +G KGH G  GL G PG  G  GD+G  GP
Sbjct: 1097 MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP 1156

Query: 1351 QGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGP 1410
             G  G +G    PG  GP G  G  G+PGP GP G +G +G  GP G  G  GPPG PGP
Sbjct: 1157 AGPSGPRGP---PGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGP 1213

Query: 1411 PGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLE----EIFGSLDSLRE 1466
            PG  I            +  D  + M+ D+A          GGL     E+  +L SL  
Sbjct: 1214 PGPGIDMSAFAGLGPREKGPDPLQYMRADQAA---------GGLRQHDAEVDATLKSLNN 1264

Query: 1467 EIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGETC 1526
            +IE +R P G++ +PARTC+DLKLCHPE   G+YW+DPNQGC  DA +VFCN    GETC
Sbjct: 1265 QIESIRSPEGSRKNPARTCRDLKLCHPEWKSGDYWIDPNQGCTLDAMKVFCNMET-GETC 1323

Query: 1527 VTPR--------------------------DDVTQFSYVDSEGSP-VGVVQLTFLRLLSV 1559
            V P                           +    FSY D   +P    VQ+TFLRLLS 
Sbjct: 1324 VYPNPANVPKKNWWSSKSKEKKHIWFGETINGGFHFSYGDDNLAPNTANVQMTFLRLLST 1383

Query: 1560 SAHQDVSYPCSGAAR---------DGPLRLRGANEDELSPETSP--YVKEFRDGCQT--- 1605
               Q+++Y C  +              L ++G+N+ E+  E +        +DGC     
Sbjct: 1384 EGSQNITYHCKNSIAYLDEAAGNLKKALLIQGSNDVEIRAEGNSRFTYTALKDGCTKHTG 1443

Query: 1606 QQGRTVLEVRTPVLEQLPVLDASFSDLGAPPRRGGVLLGPVCFM 1649
            + G+TV+E R+    +LP++D +  D+G P +  GV +GPVCF+
Sbjct: 1444 KWGKTVIEYRSQKTSRLPIIDIAPMDIGGPEQEFGVDIGPVCFL 1487



 Score =  885 bits (2287), Expect = 0.0
 Identities = 529/1191 (44%), Positives = 591/1191 (49%), Gaps = 168/1191 (14%)

Query: 263  PQSQDPTPGEEEEIL-----ESSLLPPLEEAAHGPRGLKGEKGEPAVL----EPGMLVEG 313
            P+ Q   PG+ ++I+          P  E+   G RG KGEKG P       EPG    G
Sbjct: 102  PKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPG--TPG 159

Query: 314  PPGPEGPAGLIGPPGIQGN---------------------PGPVGDPGERGPPGRAGLPG 352
             PGP GP G  GPPG+ GN                      GP+G  G RGPPG AG PG
Sbjct: 160  NPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPG 219

Query: 353  SDGAPGPPGTSLMLPFRFGSGG--GDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTG 410
              G  G PG         G  G  G  GP                    RGPPGP    G
Sbjct: 220  PQGFQGNPGEP-------GEPGVSGPMGP--------------------RGPPGP---PG 249

Query: 411  RPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKG 470
            +PG  G+ G PG  GE G  GPQG RG  G  G PG  G RG  G DGA+G  G PGVKG
Sbjct: 250  KPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKG 309

Query: 471  DRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKG 530
            + G  G  G PG  G RG  G +G  GP G  G RG+DG+ GP G PG  GP G  G  G
Sbjct: 310  ESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPG 369

Query: 531  PPGI---PGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGL-------------- 573
             PG     GP G RG +G QGP+G  G  G PGP G  G PGT G+              
Sbjct: 370  APGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAG 429

Query: 574  ----------PGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGT-------- 615
                      PGPQGA GP G KG  G+PG+ G  G  GP G PG  GP G         
Sbjct: 430  APGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEG 489

Query: 616  -------KGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKG 668
                    G  GP GP G  G PG RG  G DG+ G KG  GE+G  G  G KG  G  G
Sbjct: 490  KRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPG 549

Query: 669  DRGEVGVPGSR---GEDGPEGPKGRTGPT------GDPGPPGLMGEKGKLGVPGLPGYPG 719
              GE G+PG+R   G  G  GP+G+ GP+      G PGPPG  G +G+ GV G PG  G
Sbjct: 550  RPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKG 609

Query: 720  RQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSG 779
              G  G  G  G PGA G +G  G  G++G  G  GP GP G+RG +GA G SG +G   
Sbjct: 610  ANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGL-- 667

Query: 780  GDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPG 839
              GP GPPGE G PG QG  G  G  G  GP G+ G PG  G  G  G QG  G PG PG
Sbjct: 668  -PGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPG 726

Query: 840  VVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD---PGPPGAPGKDGPAG 896
              GP+GA+G  GP G +G PG  G PGE+G  G AG +G +GD    GP GAPGKDG   
Sbjct: 727  TDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGG-- 784

Query: 897  LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPG 956
             RG  G  G PG AG     G +G  GPPGPAGS G RGA G  G  GPPG  G  GPPG
Sbjct: 785  -RGLTGPIGPPGPAGA---NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPG 840

Query: 957  AAGE---KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKG 1013
            A G+   KG  GE G  G  G  G QGP G PGP GP GV G  G +G  G PG  G  G
Sbjct: 841  ADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG 900

Query: 1014 NKGEHGP------PGPPGPIGPVGQPGAAGA---------DGEPGARGPQGHFGAK---G 1055
              G  GP      PGPPGP GP G+ G  GA          GEPG +GP G  G K   G
Sbjct: 901  AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPG 960

Query: 1056 DEGTRGFNGPPGPIGLQ------GLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADG 1109
            D+G  G  GPPGP GL       GLPG  GE+G  G  GP G PG  G  G +G  G  G
Sbjct: 961  DDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPG 1020

Query: 1110 PQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKG 1169
            P GPPG  G  G PG +G PG  G PG  G  GVKG RGE G  G  G PG PG PGP G
Sbjct: 1021 PVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAG 1080

Query: 1170 PTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPG 1229
            PTG  G +G  G  G  G  GP G  G +G  G +GD+GE GEPG+ G  G  G  G  G
Sbjct: 1081 PTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQG 1140

Query: 1230 PLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG 1289
              G  GP+G  G+ G  G  G +G PG +G  GK G  G  GP G PGP G  G  G  G
Sbjct: 1141 LPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAG 1200

Query: 1290 QQGRPGATGQAGPPGP--------------VGPPGLPGLRGDAGAKGEKGH 1326
              G PG  G  GPPGP               GP  L  +R D  A G + H
Sbjct: 1201 PPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAGGLRQH 1251



 Score =  649 bits (1675), Expect = 0.0
 Identities = 395/879 (44%), Positives = 438/879 (49%), Gaps = 148/879 (16%)

Query: 680  GEDGPEGPKGRTGPTGDPGPPGLMGEKGKL-GVPGLPGYPGRQGPKGSLGFPGFPGASGE 738
            GE  P  P      +G PGP G  GE G +  + G  G PG QGP G  G  G  G  GE
Sbjct: 83   GECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGE 142

Query: 739  KGA---RGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPG---ERGL 792
            KGA   RG  G+ G  G  GP GP G  GP G  G   A+   G D   G       +G 
Sbjct: 143  KGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGP 202

Query: 793  PGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGP 852
             GP GP G PGP G PGP G  G PG PG+ G  G  G  GPPGPPG  G  G AG+ G 
Sbjct: 203  MGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGK 262

Query: 853  MGERGHPGPPGP---PGEQGLPGT---------------AGKEGTKGDPGPPGAPGKDGP 894
             GERG PGP G    PG  GLPG                AG  G KG+ G PG  G  GP
Sbjct: 263  AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGP 322

Query: 895  AGLRGFPGERGLPGTAGGPGLKGNE------GPSGPPGPAGSPGERGAAGSGGPIGPPGR 948
             G RG PGERG  G AG  G +GN+      GP GP GPAG PG  GA G+ G  GP G 
Sbjct: 323  MGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGA 382

Query: 949  PGPQGPPGAAGEKGVPGEKGPIGPTGR---------------DGVQGPVGLPGPAGPPGV 993
             GP+G  G  GE G PG  GP G +G                 G+ G  G PGP GPPG 
Sbjct: 383  RGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGP 442

Query: 994  AGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAA------GADGEPGARGP 1047
             G  G  G  G  G+ G  G KGE GP G PGP GP G PG A      GA GEPG  GP
Sbjct: 443  QGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGP 502

Query: 1048 QGHFGAKGDEGTRGFNGPPGPIGLQGLPGP------SGEKGETGDVGPMGPPGPPGPR-- 1099
             G  G +G  G RGF G  G  G +G PG       +G KG  GD G  G PG PG R  
Sbjct: 503  IGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGL 562

Query: 1100 ----GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGE 1155
                G AGP G  GP G PG  G  GPPG +G  G+   PG+ G PG KG  GE G+ GE
Sbjct: 563  TGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ---PGVMGFPGPKGANGEPGKAGE 619

Query: 1156 SGQPGEP---------------GPPGPKGPTGDDGPKGNPGPVGF---PGDPGPPGEG-- 1195
             G PG P               GPPGP GP G+ G +G PGP GF   PG PGPPGEG  
Sbjct: 620  KGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGK 679

Query: 1196 ----------------GPRGQDGAKGDRGEDGE---------PGQPGSPGPTGENGPPGP 1230
                            GPRG+ G  G+RG  G          PG PG+ GP G +GP GP
Sbjct: 680  PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGP 739

Query: 1231 LGKRGP---AGSPGSEGRQGGKGAKGDPGAI------GAPGK------TGPVGPAGPA-- 1273
             G +GP    G PG  G  G  G KGD G +      GAPGK      TGP+GP GPA  
Sbjct: 740  PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 799

Query: 1274 -------GKPGP---DGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1323
                   G PGP    G RG PG  G+ G PG  G AGPPG  G PG  G +G+AG KG+
Sbjct: 800  NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGD 859

Query: 1324 KGHPGLIGLIGPPGEQ------GEKGDRGLPGPQGS---PGQKGEMGIPGASGPIGPGGP 1374
             G PG  G  G PG Q      G KG RG  GP G+   PG  G +G PG++G  GP GP
Sbjct: 860  AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP 919

Query: 1375 PGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGE 1413
            PG  G  GPKGA+G +GP G  GE G+QGP G PG  GE
Sbjct: 920  PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGE 958



 Score =  421 bits (1082), Expect = e-117
 Identities = 249/548 (45%), Positives = 279/548 (50%), Gaps = 41/548 (7%)

Query: 942  PIGPPGRPGPQGPPGAAGEKGVPGE-KGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDK 1000
            PI P       G PG  G+KG PG+ K  +GP G  G QGP G  GP G  G  GE G  
Sbjct: 87   PICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAP 146

Query: 1001 GEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARG------PQGHFGAK 1054
            G  G  G+ GT GN G  GPPGPPGP G  G   A  A G     G       QG  G  
Sbjct: 147  GPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM 206

Query: 1055 GDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP---PGPRGPAGPNGADGPQ 1111
            G  G  G  G PGP G QG PG  GE G +G +GP GPPGP   PG  G AG  G  G +
Sbjct: 207  GPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGER 266

Query: 1112 GPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1171
            GPPG  G  G PG  G PG  G  G  G  G KG  G  G KGESG PGE G PGP GP 
Sbjct: 267  GPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPR 326

Query: 1172 GDDGPKGNPGPVGF---------PGDPGPPGEGGPR------GQDGAKGDRGEDGEPGQP 1216
            G  G +G  GP G          PG  GPPG  GP       G  GAKG+ G  G  G  
Sbjct: 327  GLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPE 386

Query: 1217 GSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP 1276
            G+ GP GE G PG  G  G +G+PG++G  G KG+ G PG  GAPG  GP GP GP G  
Sbjct: 387  GAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT 446

Query: 1277 GPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPP 1336
            GP G +G  G  G  G  G  G  G PGP GP G PG  G+ G +G +G PG +G IGPP
Sbjct: 447  GPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPP 506

Query: 1337 GEQGEKGDRGLPGPQGSPGQK---GEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATG-P 1392
            GE+G  G+RG PG  G  G K   GE G  G +GP G  G PG PG  G  GA+G TG P
Sbjct: 507  GERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRP 566

Query: 1393 G--------GPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPT 1444
            G        GP G  G  G PG PGP G   QP  +  P    +  +G      ++ +P 
Sbjct: 567  GDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGP--KGANGEPGKAGEKGLP- 623

Query: 1445 GGAPGSPG 1452
             GAPG  G
Sbjct: 624  -GAPGLRG 630



 Score = 38.1 bits (87), Expect = 0.071
 Identities = 32/96 (33%), Positives = 39/96 (40%), Gaps = 18/96 (18%)

Query: 1369 IGPGGPPGLPGPAGPKGAKGATGPGGPKGEKG-------VQGPPGHPGPPGEVIQPLPIQ 1421
            + P  P G   P  P     A+G  GPKG+KG       + GP G PGP G    P   Q
Sbjct: 76   LSPEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQG----PAGEQ 131

Query: 1422 MPK-----KTRRSVDGSRLMQEDEAIPTGGAPGSPG 1452
             P+     K  +   G R    +   P  G PG PG
Sbjct: 132  GPRGDRGDKGEKGAPGPRGRDGEPGTP--GNPGPPG 165


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score = 1157 bits (2994), Expect = 0.0
 Identities = 654/1419 (46%), Positives = 768/1419 (54%), Gaps = 95/1419 (6%)

Query: 294  GLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGS 353
            G KG+KGEP  ++  +  +GPPGP+GPAG  GP G +G+ G  G PG RG  G  G PG+
Sbjct: 32   GPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGN 91

Query: 354  DGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQA---QAILQQARLALRGPPGPMGYTG 410
             G PGPPG     P   G GG     +    + +A   Q  + Q  +   GP GP G  G
Sbjct: 92   PGPPGPPGP----PGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAG 147

Query: 411  RPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKG 470
             PGP G  G+PG  GE G  GP GPRGP G   PPGK G  G AG  G  G  G PG +G
Sbjct: 148  APGPQGFQGNPGEPGEPGVSGPMGPRGPPG---PPGKPGDDGEAGKPGKAGERGPPGPQG 204

Query: 471  DRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKG 530
             RGF G PGLPG KGHRG  G  G  G  G  G +G+ G  G  G PG  GPRGL G +G
Sbjct: 205  ARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERG 264

Query: 531  PPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQG 590
              G  G  G RG DG  GP G  GP G  G PG  G PG +G  GP GA GP G +GP+G
Sbjct: 265  RTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRG 324

Query: 591  KPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKG 650
            +PG PG PG  G  G+PG +G PG KG+ G  G  G  G+PGPRG  G  G  G  G KG
Sbjct: 325  EPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKG 384

Query: 651  EKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLG 710
            + GE G  GFKG+ G KG+ G  G  G+ G  G EG +G  G  G  GP G  GE+G  G
Sbjct: 385  QTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPG 444

Query: 711  VPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG---ERGPTGPRGQRGPRG 767
              G PG  G  GPKG+ G  G  G +G KGA G  G+ G  G    RG TG  G  GP+G
Sbjct: 445  NRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQG 504

Query: 768  ATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK---DGLPGHPGQRG 824
              G SGA G  G  GP GP G RG PG  G   FPGPKG  G PGK    GLPG PG RG
Sbjct: 505  KVGPSGAPGEDGRPGPPGPQGARGQPGVMG---FPGPKGANGEPGKAGEKGLPGAPGLRG 561

Query: 825  EVGFQGKTGPPGPPGVVGPQGAAGETG---PMGERGHPGPPGPPGEQGLPGTAGKEGTKG 881
              G  G+TG  GPPG  GP G  GE G   P G +G PGPPGPPGE       GK G +G
Sbjct: 562  LPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGE------GGKPGDQG 615

Query: 882  DPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGG 941
             PG  GAPG  GP G RGFPGERG PG  G  G +G  G  G  GP G+ G  G  G+ G
Sbjct: 616  VPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQG 675

Query: 942  PIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 1001
            P G  G PG +G  G AG KG  G+ G  GP G  G  G  GL GP GPPG AG +G+KG
Sbjct: 676  PPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKG 735

Query: 1002 EVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRG 1061
            EVG PG  G+ G +G  G  G  GP GP G  G  GADG+PGA+G QG  G KGD G  G
Sbjct: 736  EVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPG 795

Query: 1062 FNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLG 1121
              GP G  G QG  G +G KG  G  GP G  G PG  G  GP G++G  GPPG  G  G
Sbjct: 796  PQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSG 855

Query: 1122 PPGEKGEPGESGSPGIQGEPGVKGPRG---ERGEKGESGQPGEPGPPGPKGPTGDDGPKG 1178
              G KG  G+SG PG  GEPG++GP G   E+GE G+ G  G  GPPGP+G  G  G  G
Sbjct: 856  KDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVG 915

Query: 1179 NPGPVG---FPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRG 1235
             PG  G   FPG PGP GE G +G  GA GDRG  G  G PG  GP GE   PG  G  G
Sbjct: 916  LPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGE---PGREGSPG 972

Query: 1236 PAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPG 1295
              G PG +G  G KG +G+ GA+GAPG  GP G  GPAG  G  G RG  G+ G  G  G
Sbjct: 973  ADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSG 1032

Query: 1296 ATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPG 1355
              G  G  GP GP G  G  G+ G +G KGH G  GL G PG  G  GD+G  GP G  G
Sbjct: 1033 PAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSG 1092

Query: 1356 QKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVI 1415
             +G    PG  GP G  G  G+PGP GP G +G +G  GP G  G  GPPG PGPPG  I
Sbjct: 1093 PRGP---PGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGI 1149

Query: 1416 QPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLE----EIFGSLDSLREEIEQM 1471
                        +  D  + M+ D+A          GGL     E+  +L SL  +IE +
Sbjct: 1150 DMSAFAGLGPREKGPDPLQYMRADQAA---------GGLRQHDAEVDATLKSLNNQIESI 1200

Query: 1472 RRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGETCVTPR- 1530
            R P G++ +PARTC+DLKLCHPE   G+YW+DPNQGC  DA +VFCN    GETCV P  
Sbjct: 1201 RSPEGSRKNPARTCRDLKLCHPEWKSGDYWIDPNQGCTLDAMKVFCNMET-GETCVYPNP 1259

Query: 1531 -------------------------DDVTQFSYVDSEGSP-VGVVQLTFLRLLSVSAHQD 1564
                                     +    FSY D   +P    VQ+TFLRLLS    Q+
Sbjct: 1260 ANVPKKNWWSSKSKEKKHIWFGETINGGFHFSYGDDNLAPNTANVQMTFLRLLSTEGSQN 1319

Query: 1565 VSYPCSGAAR---------DGPLRLRGANEDELSPETSP--YVKEFRDGCQT---QQGRT 1610
            ++Y C  +              L ++G+N+ E+  E +        +DGC     + G+T
Sbjct: 1320 ITYHCKNSIAYLDEAAGNLKKALLIQGSNDVEIRAEGNSRFTYTALKDGCTKHTGKWGKT 1379

Query: 1611 VLEVRTPVLEQLPVLDASFSDLGAPPRRGGVLLGPVCFM 1649
            V+E R+    +LP++D +  D+G P +  GV +GPVCF+
Sbjct: 1380 VIEYRSQKTSRLPIIDIAPMDIGGPEQEFGVDIGPVCFL 1418



 Score =  885 bits (2287), Expect = 0.0
 Identities = 529/1191 (44%), Positives = 591/1191 (49%), Gaps = 168/1191 (14%)

Query: 263  PQSQDPTPGEEEEIL-----ESSLLPPLEEAAHGPRGLKGEKGEPAVL----EPGMLVEG 313
            P+ Q   PG+ ++I+          P  E+   G RG KGEKG P       EPG    G
Sbjct: 33   PKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPG--TPG 90

Query: 314  PPGPEGPAGLIGPPGIQGN---------------------PGPVGDPGERGPPGRAGLPG 352
             PGP GP G  GPPG+ GN                      GP+G  G RGPPG AG PG
Sbjct: 91   NPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPG 150

Query: 353  SDGAPGPPGTSLMLPFRFGSGG--GDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTG 410
              G  G PG         G  G  G  GP                    RGPPGP    G
Sbjct: 151  PQGFQGNPGEP-------GEPGVSGPMGP--------------------RGPPGP---PG 180

Query: 411  RPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKG 470
            +PG  G+ G PG  GE G  GPQG RG  G  G PG  G RG  G DGA+G  G PGVKG
Sbjct: 181  KPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKG 240

Query: 471  DRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKG 530
            + G  G  G PG  G RG  G +G  GP G  G RG+DG+ GP G PG  GP G  G  G
Sbjct: 241  ESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPG 300

Query: 531  PPGI---PGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGL-------------- 573
             PG     GP G RG +G QGP+G  G  G PGP G  G PGT G+              
Sbjct: 301  APGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAG 360

Query: 574  ----------PGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGT-------- 615
                      PGPQGA GP G KG  G+PG+ G  G  GP G PG  GP G         
Sbjct: 361  APGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEG 420

Query: 616  -------KGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKG 668
                    G  GP GP G  G PG RG  G DG+ G KG  GE+G  G  G KG  G  G
Sbjct: 421  KRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPG 480

Query: 669  DRGEVGVPGSR---GEDGPEGPKGRTGPT------GDPGPPGLMGEKGKLGVPGLPGYPG 719
              GE G+PG+R   G  G  GP+G+ GP+      G PGPPG  G +G+ GV G PG  G
Sbjct: 481  RPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKG 540

Query: 720  RQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSG 779
              G  G  G  G PGA G +G  G  G++G  G  GP GP G+RG +GA G SG +G   
Sbjct: 541  ANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGL-- 598

Query: 780  GDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPG 839
              GP GPPGE G PG QG  G  G  G  GP G+ G PG  G  G  G QG  G PG PG
Sbjct: 599  -PGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPG 657

Query: 840  VVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD---PGPPGAPGKDGPAG 896
              GP+GA+G  GP G +G PG  G PGE+G  G AG +G +GD    GP GAPGKDG   
Sbjct: 658  TDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGG-- 715

Query: 897  LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPG 956
             RG  G  G PG AG     G +G  GPPGPAGS G RGA G  G  GPPG  G  GPPG
Sbjct: 716  -RGLTGPIGPPGPAGA---NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPG 771

Query: 957  AAGE---KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKG 1013
            A G+   KG  GE G  G  G  G QGP G PGP GP GV G  G +G  G PG  G  G
Sbjct: 772  ADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG 831

Query: 1014 NKGEHGP------PGPPGPIGPVGQPGAAGA---------DGEPGARGPQGHFGAK---G 1055
              G  GP      PGPPGP GP G+ G  GA          GEPG +GP G  G K   G
Sbjct: 832  AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPG 891

Query: 1056 DEGTRGFNGPPGPIGLQ------GLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADG 1109
            D+G  G  GPPGP GL       GLPG  GE+G  G  GP G PG  G  G +G  G  G
Sbjct: 892  DDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPG 951

Query: 1110 PQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKG 1169
            P GPPG  G  G PG +G PG  G PG  G  GVKG RGE G  G  G PG PG PGP G
Sbjct: 952  PVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAG 1011

Query: 1170 PTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPG 1229
            PTG  G +G  G  G  G  GP G  G +G  G +GD+GE GEPG+ G  G  G  G  G
Sbjct: 1012 PTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQG 1071

Query: 1230 PLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG 1289
              G  GP+G  G+ G  G  G +G PG +G  GK G  G  GP G PGP G  G  G  G
Sbjct: 1072 LPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAG 1131

Query: 1290 QQGRPGATGQAGPPGP--------------VGPPGLPGLRGDAGAKGEKGH 1326
              G PG  G  GPPGP               GP  L  +R D  A G + H
Sbjct: 1132 PPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAGGLRQH 1182



 Score =  374 bits (960), Expect = e-103
 Identities = 229/539 (42%), Positives = 263/539 (48%), Gaps = 92/539 (17%)

Query: 1002 EVGDPGQKGTKGNKGE----HGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1057
            +V  PG KG KG  G+     GP GPPGP GP G+ G  G  G+ G +G  G  G  G+ 
Sbjct: 27   DVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 86

Query: 1058 GTRGFNGPPGPIGLQGLPGPSG-----------EKGETGDVGPM-GPPGPPGPRGPAGPN 1105
            GT G  GPPGP G  G PG  G           EK     +G M GP GP GPRGP GP 
Sbjct: 87   GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 146

Query: 1106 GADGPQ---------------GPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGER 1150
            GA GPQ               GP G  G  GPPG+ G+ GE+G PG  GE G  GP+G R
Sbjct: 147  GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGAR 206

Query: 1151 ------------------------------GEKGESGQPGEPGPPGPKGPTGDDGPKGNP 1180
                                          G KGESG PGE G PGP GP G  G +G  
Sbjct: 207  GFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRT 266

Query: 1181 GPVGF---------PGDPGPPGEGGPR------GQDGAKGDRGEDGEPGQPGSPGPTGEN 1225
            GP G          PG  GPPG  GP       G  GAKG+ G  G  G  G+ GP GE 
Sbjct: 267  GPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEP 326

Query: 1226 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLP 1285
            G PG  G  G +G+PG++G  G KG+ G PG  GAPG  GP GP GP G  GP G +G  
Sbjct: 327  GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQT 386

Query: 1286 GSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDR 1345
            G  G  G  G  G  G PGP GP G PG  G+ G +G +G PG +G IGPPGE+G  G+R
Sbjct: 387  GEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNR 446

Query: 1346 GLPGPQGSPGQK---GEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATG-PG-------- 1393
            G PG  G  G K   GE G  G +GP G  G PG PG  G  GA+G TG PG        
Sbjct: 447  GFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKV 506

Query: 1394 GPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1452
            GP G  G  G PG PGP G   QP  +  P    +  +G      ++ +P  GAPG  G
Sbjct: 507  GPSGAPGEDGRPGPPGPQGARGQPGVMGFPGP--KGANGEPGKAGEKGLP--GAPGLRG 561


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 1138 bits (2943), Expect = 0.0
 Identities = 646/1412 (45%), Positives = 756/1412 (53%), Gaps = 134/1412 (9%)

Query: 316  GPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGG 375
            G EGP G  GP   +G  GP G PG  G PG+ GLPG  G PGPPG         G GG 
Sbjct: 109  GVEGPKGDTGP---RGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPP-------GLGGN 158

Query: 376  DKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKG---ESGDLGP 432
                  A Q +          +++ GP GP G  G PGP G PG  G +G   E G+ G 
Sbjct: 159  -----FAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGA 213

Query: 433  QGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGA 492
             GP GP+G  GPPGK G  G AG  G  G  G PG +G RG  G  GLPG KGHRG +G 
Sbjct: 214  SGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGL 273

Query: 493  QGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGS 552
             G  G  G  G +G+ G  G  G PG+ GPRGL G +G PG PGP G RG DG  G  G 
Sbjct: 274  DGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGP 333

Query: 553  LGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGP 612
             GP G  GPPG  G  G +G  GPQG  G  G +G +G+PG PG  G+ GP G+PG +G 
Sbjct: 334  PGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQ 393

Query: 613  PGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGE 672
            PG KG  G  G  G  G+PG RG  G  G  G  G KG  GE G PG KGD G KG+ G 
Sbjct: 394  PGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGP 453

Query: 673  VGV---PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGF 729
            VGV   PG  GE+G  G +G  GPTG PGPPG  G  G  G PG  G  G +GP G  G 
Sbjct: 454  VGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGS 513

Query: 730  PGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE 789
            PG  G  G  G  G  G++G  G +G TG  G  GP G TG  G  G  G  GP GPPG 
Sbjct: 514  PGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGA 573

Query: 790  RGLPGPQGPNGFPGPKGPPGPPGKDG---LPGHPGQRGEVGFQGKTGPPGPPGVVGPQGA 846
            RG  G  G   FPGPKG  G PGK G   +PG PG  G  G  G+ G  GPPG  GP G 
Sbjct: 574  RGQAGVMG---FPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGE 630

Query: 847  AGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGL 906
             GE GP G  G  G PGP G    PG AGK G +G PG  GAPG  G  G RGFPGERG+
Sbjct: 631  RGEQGPAGSPGFQGLPGPAGP---PGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGV 687

Query: 907  ---PGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGV 963
               PG AG  G  G  G  G  G AG+PG  G+ G+ G  G PG  G  G PG  G++G 
Sbjct: 688  QGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGD 747

Query: 964  PGEKGPIGPTGRDGVQG---PVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 1020
             G KG  G  G+DGV+G   P+G PGPAG PG  GE G  G  G  G +G  G++GE   
Sbjct: 748  AGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGE--- 804

Query: 1021 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1080
            PGPPGP G  G P   GADG+PGA+G  G  GAKGD       GPPGP G  G PGP   
Sbjct: 805  PGPPGPAGFAGPP---GADGQPGAKGEPGDAGAKGDA------GPPGPAGPAGPPGP--- 852

Query: 1081 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1140
                  +G +G PG  G RG AGP GA    G PG  G +GPPG  G  G  G PG  G+
Sbjct: 853  ------IGNVGAPGAKGARGSAGPPGA---TGFPGAAGRVGPPGPSGNAGPPGPPGPAGK 903

Query: 1141 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQ 1200
             G KGPRG   E G +G+PGE GPPGP GP G+ G  G  GP G PG PGP G  G RG 
Sbjct: 904  EGGKGPRG---ETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGV 960

Query: 1201 DGAKGDRGE---------DGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGA 1251
             G  G RGE          GEPG+ G  G +GE GPPGP+G  G AG PG  GR+G  GA
Sbjct: 961  VGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGA 1020

Query: 1252 KGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGL 1311
            +G PG  G+PG  G  G  GPAG PG  G  G PG VG  G+ G  G+ GP GP GP G 
Sbjct: 1021 EGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGP 1080

Query: 1312 PGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGP 1371
             G RG AG +G +G  G  G  G  G +G +G  GL GP G PG  GE G  GASGP GP
Sbjct: 1081 VGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGP 1140

Query: 1372 GGPP------------GLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1419
             GPP            GLPGP GP G +G TG  GP G  G  GPPG PGPP        
Sbjct: 1141 RGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSF 1200

Query: 1420 IQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQD 1479
            +  P +  ++ DG R  + D+A              E+  +L SL ++IE +R P G++ 
Sbjct: 1201 LPQPPQ-EKAHDGGRYYRADDANVVRDRD------LEVDTTLKSLSQQIENIRSPEGSRK 1253

Query: 1480 SPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGETCVTPRD-------- 1531
            +PARTC+DLK+CH +   GEYW+DPNQGC  DA +VFCN    GETCV P          
Sbjct: 1254 NPARTCRDLKMCHSDWKSGEYWIDPNQGCNLDAIKVFCNMET-GETCVYPTQPSVAQKNW 1312

Query: 1532 -------------------DVTQFSYVDSEGSPVGV-VQLTFLRLLSVSAHQDVSYPCSG 1571
                               D  QF Y      P  V +QLTFLRL+S  A Q+++Y C  
Sbjct: 1313 YISKNPKDKRHVWFGESMTDGFQFEYGGQGSDPADVAIQLTFLRLMSTEASQNITYHCKN 1372

Query: 1572 AA-----RDGPLR----LRGANEDELSPE-TSPYVKEFR-DGCQTQQ---GRTVLEVRTP 1617
            +      + G L+    L+G+NE E+  E  S +      DGC +     G+TV+E +T 
Sbjct: 1373 SVAYMDQQTGNLKKALLLQGSNEIEIRAEGNSRFTYSVTVDGCTSHTGAWGKTVIEYKTT 1432

Query: 1618 VLEQLPVLDASFSDLGAPPRRGGVLLGPVCFM 1649
               +LP++D +  D+GAP +  G  +GPVCF+
Sbjct: 1433 KTSRLPIIDVAPLDVGAPDQEFGFDVGPVCFL 1464



 Score =  736 bits (1900), Expect = 0.0
 Identities = 422/906 (46%), Positives = 465/906 (51%), Gaps = 96/906 (10%)

Query: 598  PGSDGPPGH-----PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEK 652
            PG++ P G      P     P  +   G  GP+G  G  GPRG  G  G  G+ G  G  
Sbjct: 82   PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLP 141

Query: 653  GEDGFPGFKGDIGVKGDRGEVGVPG----SRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 708
            G  G PG  G  G+ G+       G    S G     GP G +GP G PGPPG  G +G 
Sbjct: 142  GPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGF 201

Query: 709  LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPR-------- 760
             G PG PG PG  GP G  G PG PG +G+ G  G  G+ G RG  GP G R        
Sbjct: 202  QGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGL 261

Query: 761  -GQRGPRGATGKSGAKGTSGGDGPH---GPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL 816
             G +G RG +G  GAKG +G  GP    G PGE G PG  GP G PG +G PG PG  G 
Sbjct: 262  PGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGA 321

Query: 817  PGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGK 876
             G+ G  G  G  G TGP GPPG  G  GA GE GP G RG  GP G  GE G PG AG 
Sbjct: 322  RGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGA 381

Query: 877  EGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGA 936
             G  G+PG  G P   G  G  G PG  G PG  G  G  G +GP GPPGP G+ GE GA
Sbjct: 382  AGPAGNPGADGQP---GAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGA 438

Query: 937  AGSGGPIGPPGRPGP---QGPPGAAGEKGVPGEKGPIGPT------------------GR 975
             GS G  G  G PGP   QGPPG AGE+G  G +G  GPT                  G 
Sbjct: 439  PGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGA 498

Query: 976  DGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1035
            DGV GP G  G  G PG AG  G  GE G PG+ G  G KG  G PG PGP G  G PG 
Sbjct: 499  DGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGP 558

Query: 1036 AGADGEPGARGPQGHFGAKGDEGTRGFNGP------PGPIGLQGLPGPSGEKGETGDVGP 1089
            AG DG PG  GP    GA+G  G  GF GP      PG  G +G+PGP G  G  G  G 
Sbjct: 559  AGQDGRPGPPGPP---GARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGE 615

Query: 1090 MGPPGPPGPRGPAGPNGADGPQGPPG--GV-GNLGPPGEKGEPGESGSPGIQGEPGVKGP 1146
             G  GPPGP GPAG  G  GP G PG  G+ G  GPPGE G+PGE G PG  G PG  G 
Sbjct: 616  AGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGA 675

Query: 1147 RGERGEKGESGQPGEPGPPGPKGPT---GDDGPKGN------PGPVGFPGDPGPPGEGGP 1197
            RGERG  GE G  G PGP GP+G     G+DG KG+      PG  G PG  G PGE G 
Sbjct: 676  RGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGA 735

Query: 1198 RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGA 1257
             G  G KGDRG+ G  G  GSPG  G  G  GP+G  GPAG+PG +G  G  G  G  GA
Sbjct: 736  AGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGA 795

Query: 1258 IGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGP--------- 1308
             GAPG  G  GP GPAG  GP G  G PG+ G+ G  GA G AGPPGP GP         
Sbjct: 796  RGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGN 855

Query: 1309 ---PGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGA 1365
               PG  G RG AG  G  G PG  G +GPPG  G  G  G PGP G  G KG  G  G 
Sbjct: 856  VGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGP 915

Query: 1366 SGPIGPGGPPGLPGPAGPKGAKGATGPGGP------------------KGEKGVQGPPGH 1407
            +G  G  GPPG PGPAG KG+ GA GP G                    G++G +G PG 
Sbjct: 916  AGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGL 975

Query: 1408 PGPPGE 1413
            PGP GE
Sbjct: 976  PGPSGE 981



 Score =  597 bits (1538), Expect = e-170
 Identities = 375/867 (43%), Positives = 419/867 (48%), Gaps = 156/867 (17%)

Query: 286  EEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPP 345
            E    GPRG +G +G          V G PGP GPAG  GP G  G  G  G  G  G P
Sbjct: 354  EAGPQGPRGSEGPQG----------VRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAP 403

Query: 346  GRAGLPGSDGA------------PGPPGTSLMLPFRFGSGG-----GDKGPVVAAQEAQA 388
            G AG PG  GA            PGP G S   P   GS G     G+ GPV    +   
Sbjct: 404  GIAGAPGFPGARGPSGPQGPGGPPGPKGNSGE-PGAPGSKGDTGAKGEPGPV--GVQGPP 460

Query: 389  QAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGP---- 444
                ++ +   RG PGP G  G PG  G PGS G  G  G  GP+GP G +G  GP    
Sbjct: 461  GPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPK 520

Query: 445  --PGKAGRRGRAGADGARGMPGDPGVKGD---------RGFDGLPGLPGEKGHRGDTGAQ 493
              PG+AGR G AG  GA+G+ G PG  G           G DG PG PG  G RG  G  
Sbjct: 521  GSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVM 580

Query: 494  GLPGPPGEDGERGDDGEIGPRGLPGESGPRGL---LGPKGPPGIPGPPGVRGMDGP---- 546
            G PGP G  GE G  GE G  G PG  GP G     G +GPPG  GP G RG  GP    
Sbjct: 581  GFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSP 640

Query: 547  --QGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHG---EKGPQGKPGLPGMPGSD 601
              QG  G  GP GE G PG+QG PG  G PGP GA G  G   E+G QG PG  G  G++
Sbjct: 641  GFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGAN 700

Query: 602  GPPGH------------------PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGV---D 640
            G PG+                  PG +G PG +G  G  GP+G  G  GP+G  G    D
Sbjct: 701  GAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKD 760

Query: 641  GIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV---PGSRGEDGPEGPKGRTGPTGDP 697
            G+RGL G  G  G  G PG KG+ G  G  G  G    PG RGE GP GP G  GP G  
Sbjct: 761  GVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGAD 820

Query: 698  GPPGLMGE------KGKLGVPGLPGYPGRQGPKGSLGFPG---------------FPGAS 736
            G PG  GE      KG  G PG  G  G  GP G++G PG               FPGA+
Sbjct: 821  GQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAA 880

Query: 737  GEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQ 796
            G  G  G SG +GP G  GP G  G +GPRG TG +G  G  G  GP GP GE+G PG  
Sbjct: 881  GRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGAD 940

Query: 797  GPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGER 856
            GP G PG  GP G  G+ G+ G PGQRGE GF G  GP G PG  GP GA+GE GP G  
Sbjct: 941  GPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPM 1000

Query: 857  GHPGPPGPPGE---------QGLPGTAGKEGTKGD---------PGPPGAPGKDGPAGLR 898
            G PG  GPPGE         +G PG  G  G KGD         PG PGAPG  GP G  
Sbjct: 1001 GPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPA 1060

Query: 899  GFPGERGLPGTAG-----------------GP-------------GLKGNEGPSG---PP 925
            G  G+RG  G AG                 GP             G+KG+ G SG   PP
Sbjct: 1061 GKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPP 1120

Query: 926  GPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLP 985
            GP GSPGE+G +G+ GP GP G PG  G PG  G  G+PG  GP GP GR G  GPVG P
Sbjct: 1121 GPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPP 1180

Query: 986  G---PAGPPGVAGEDGDKGEVGDPGQK 1009
            G   P GPPG      D   +  P Q+
Sbjct: 1181 GPPGPPGPPGPPSAGFDFSFLPQPPQE 1207


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 1123 bits (2904), Expect = 0.0
 Identities = 643/1437 (44%), Positives = 764/1437 (53%), Gaps = 126/1437 (8%)

Query: 293  RGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPG---RAG 349
            RG KG+KGEP ++     + G PGP GP G  GP   +G  GP G PG RGP G     G
Sbjct: 109  RGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGP---RGERGPKGRPGPRGPQGIDGEPG 165

Query: 350  LPGSDGAPGPPG-------TSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGP 402
            +PG  GAPGPPG         L  PF     G D+   + +Q       L    +   GP
Sbjct: 166  VPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVG-----LMPGSVGPVGP 220

Query: 403  PGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGM 462
             GP G  G+ G  G  G PG  G+ G +GP G RGP+G  G PG+ G  GR G  G  G 
Sbjct: 221  RGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGF 280

Query: 463  PGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGE------IGPRGL 516
             G PG +G  G  GLPGL G +GH+G  G +G  G PG  GE G  G       +GPRG+
Sbjct: 281  AGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGM 340

Query: 517  PGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGP 576
            PGE   RG LGP+G PG  G  G+ G  GP GP G  G  G PG PG +G  G  G  GP
Sbjct: 341  PGE---RGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGP 397

Query: 577  QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGV 636
            +G  G  GE GP G  G PG+PG+ G  G PG +GP G+ G  GP G  GP G PGP+G 
Sbjct: 398  EGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGS 457

Query: 637  KGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGD 696
             G  GIRG      + G+ G PGFKG+ G KG+ G  G+   +G  GP G +G+ GP GD
Sbjct: 458  TGPQGIRG------QPGDPGVPGFKGEAGPKGEPGPHGI---QGPIGPPGEEGKRGPRGD 508

Query: 697  PGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGP 756
            PG  G  G  G+ G PG  G+PG      S G PG  GA GE+G  G SG  G +G+ G 
Sbjct: 509  PGTVGPPGPVGERGAPGNRGFPG------SDGLPGPKGAQGERGPVGSSGPKGSQGDPGR 562

Query: 757  TGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGF---PGPKGPPGPPGK 813
             G  G  G RG TG  G +G  G  GP G PGE G PGP G  G    PG  G PGP G 
Sbjct: 563  PGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGS 622

Query: 814  DGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGT 873
             G PG PG+ G  G  G+ G PG  G VGP G  G  G  GERG  GPPGP G QGLPG 
Sbjct: 623  SGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGP 682

Query: 874  ------AGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGP 927
                   GK G +G PG PGA G  GP G RG PGERG PG  G PG KG  G  GP GP
Sbjct: 683  PGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGP 742

Query: 928  AGSPGERGAAGSGGPIGPPGRPGPQG---PPGAAGEKGVPGEKGPIGPTGRDGVQG---P 981
             GSPG  G  G  GP G  G PG +G    PG  G++G  GEKG  G  G DG +G   P
Sbjct: 743  KGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGP 802

Query: 982  VGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGP---PGPIGPVGQPGAAGA 1038
            +G PGPAGP G  GE G +G VG PG +G  G++GE+GP G     GP GP GQPG  G 
Sbjct: 803  LGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGE 862

Query: 1039 DGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGP 1098
             GEPG +G  G        G +G  G PGP G  G+PG  G +G  G  G  G PG  G 
Sbjct: 863  PGEPGQKGDAG------SPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGR 916

Query: 1099 RGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQ 1158
             GP GP GA GP GP G  G  GPPG +G+PG  G  G +G  G  G  G++G+ GE GQ
Sbjct: 917  VGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQ 976

Query: 1159 PGEPGPPGPKGPTGDDGPKGNP---GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQ 1215
            PG  GPPGP G TG  G  G P   G  G PG PGP G  G  G  GA GD+G  G  G 
Sbjct: 977  PGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGP 1036

Query: 1216 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1275
            PGS GP GE GP GP G     G+PG +G  G +G +GDPG  G PG  G  G  GP G 
Sbjct: 1037 PGSNGPVGEPGPEGPAGN---DGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGA 1093

Query: 1276 PGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGH---PGLIGL 1332
            PG  G RG PGS G  G PG  G+ G PGP GP G  G  GD G +G+KGH    GL GL
Sbjct: 1094 PGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGL 1153

Query: 1333 IGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGP 1392
             GPPG  GE+G  G+PGP G  G       PG  GP G  G PG  GP GP G +G+ G 
Sbjct: 1154 PGPPGPNGEQGSAGIPGPFGPRGP------PGPVGPSGKEGNPGPLGPIGPPGVRGSVGE 1207

Query: 1393 GGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1452
             GP+G  G  GPPG PGPPG +   L   M        D      ED+A P       PG
Sbjct: 1208 AGPEGPPGEPGPPGPPGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDKNKTDPG 1267

Query: 1453 GLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDA 1512
                +  +L SL  +IE MR P G++  PARTC DLKLCH     GEYW+DPNQG   DA
Sbjct: 1268 ----VHATLKSLSSQIETMRSPDGSKKHPARTCDDLKLCHSAKQSGEYWIDPNQGSVEDA 1323

Query: 1513 FRVFCNFTAGGETCVT------PR--------------------DDVTQFSYVDSEGSPV 1546
             +V+CN    GETC++      PR                    +  +QF+Y D +    
Sbjct: 1324 IKVYCNMET-GETCISANPSSVPRKTWWASKSPDNKPVWYGLDMNRGSQFAYGDHQSPNT 1382

Query: 1547 GVVQLTFLRLLSVSAHQDVSYPCSGAA--RDGPLR-------LRGANEDELSPETSPYVK 1597
             + Q+TFLRLLS  A Q+++Y C  +    D   +       L+GAN+ ++  E +   +
Sbjct: 1383 AITQMTFLRLLSKEASQNITYICKNSVGYMDDQAKNLKKAVVLKGANDLDIKAEGNIRFR 1442

Query: 1598 --EFRDGCQTQQ---GRTVLEVRTPVLEQLPVLDASFSDLGAPPRRGGVLLGPVCFM 1649
                +D C  +    G+TV E RT  + +LP++D +  D+G   +  GV +GPVCF+
Sbjct: 1443 YIVLQDTCSKRNGNVGKTVFEYRTQNVARLPIIDLAPVDVGGTDQEFGVEIGPVCFV 1499



 Score =  844 bits (2181), Expect = 0.0
 Identities = 493/1107 (44%), Positives = 560/1107 (50%), Gaps = 128/1107 (11%)

Query: 240  QPHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEK 299
            +P  AQ +   + S L       P S  P      + L+       ++   GP G  GE 
Sbjct: 189  RPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQG------QQGGAGPTGPPGEP 242

Query: 300  GEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGP 359
            G+             PGP GP G  GP G  G PG  G+PG  G PG  G  GS GA G 
Sbjct: 243  GD-------------PGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGF 289

Query: 360  PGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPG 419
            PG                                     L G  G  G+ G  GP G+ G
Sbjct: 290  PGAP----------------------------------GLPGLKGHRGHKGLEGPKGEVG 315

Query: 420  SPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGAD---GARGMPGDPGVKGDRGF-- 474
            +PG KGE+G  GP G  GP G  G PG+ GR G  GA    GA GMPG PG  G  G   
Sbjct: 316  APGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPG 375

Query: 475  -DGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGP-- 531
              G PG PG KG  G TGA+G  GP G+ GE G  G +G  GLPG  G  G  G KGP  
Sbjct: 376  SSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTG 435

Query: 532  -PGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQG 590
             PG  GPPG  G  G  GP+GS GPQG  G PG  G PG +G  GP+G  GPHG +GP G
Sbjct: 436  SPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIG 495

Query: 591  KPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKG 650
                        PPG  GK GP G  G  GP GP G  G PG RG  G DG+ G KG +G
Sbjct: 496  ------------PPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQG 543

Query: 651  EKGEDGFPGFKGDIGVKGDRGEVGVPGSR---GEDGPEGPKGRTGPTGDPGPPGLMGEKG 707
            E+G  G  G KG  G  G  GE G+PG+R   G  G +GP+G+ GP G PG  G  G  G
Sbjct: 544  ERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPG 603

Query: 708  KLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGA---RGLSGKSGPRGERGPTGPRGQRG 764
             +G+ G PG  G  GPKGS G PG PG +G  G    RG  GK G  G  GP GP G  G
Sbjct: 604  SIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAG 663

Query: 765  PRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGP------PGKDGLPG 818
             RG  G  G  G  G  GP GPPGE G PG QG  G PG  GP GP      PG+ G PG
Sbjct: 664  ERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPG 723

Query: 819  HPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGP------MGERGHPGPPGPP------G 866
              G  GE G  G  GP GP G  GP G  G+TGP       GERG  G PGP       G
Sbjct: 724  ITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIG 783

Query: 867  EQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGL---PGTAGGPGLKGNEGP-- 921
            E+G  GTAG +G +G PGP G PG  GP G +G PG RGL   PG+ G PG +G  GP  
Sbjct: 784  EKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTG 843

Query: 922  ----SGPPGP---------AGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKG 968
                +GP GP          G PG++G AGS GP G  G PGP GP G  G KG  G +G
Sbjct: 844  AVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQG 903

Query: 969  PIGPT------GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPG 1022
            P G T      GR G  GP G PGPAGP G  G++G  G  GDPG  G  G++G  GPPG
Sbjct: 904  PPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPG 963

Query: 1023 PPGPIGPVGQPGAAGADGEP---GARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSG 1079
             PG  G  G+ G  G DG P   G  G +G  G  G  G RG  G PGP G  G  GP+G
Sbjct: 964  GPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTG 1023

Query: 1080 EKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQG 1139
              G+ G  GP+GPPG  GP G  GP G  G  G PG  G +G  G++G+PG +G PG QG
Sbjct: 1024 ATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQG 1083

Query: 1140 EPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRG 1199
             PG  GP G  G   ++GQ G+PG  GP GP G  G +G PGP G  GD G  G+ G RG
Sbjct: 1084 APGTPGPVGAPG---DAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRG 1140

Query: 1200 QDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIG 1259
            Q G +G  G  G PG PG  G  G  G PGP G RGP G  G  G++G  G  G  G  G
Sbjct: 1141 QKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPG 1200

Query: 1260 APGKTGPVGPAGPAGKPGPDGLRGLPG 1286
              G  G  GP GP G+PGP G  G PG
Sbjct: 1201 VRGSVGEAGPEGPPGEPGPPGPPGPPG 1227



 Score =  747 bits (1928), Expect = 0.0
 Identities = 446/1016 (43%), Positives = 500/1016 (49%), Gaps = 138/1016 (13%)

Query: 561  PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQG 620
            PPG+   P     PG        G KG +G+PGL  +P   G  G PG  GPP   G+QG
Sbjct: 88   PPGEC-CPVCSQTPGGGNTNFGRGRKGQKGEPGL--VPVVTGIRGRPGPAGPP---GSQG 141

Query: 621  PSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPG--------------------- 659
            P G +GP G PGPRG +G+DG  G+ G  G  G  G P                      
Sbjct: 142  PRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEK 201

Query: 660  ---------FKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLG 710
                       G +G  G RG  G+ G +G  GP GP G  G  G  GP G  G +G  G
Sbjct: 202  SGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPG 261

Query: 711  VPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATG 770
             PG  G PGR G  G +GF G PGA G  GA GL G  G RG +G  GP+G+ G  G+ G
Sbjct: 262  KPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKG 321

Query: 771  KSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQG 830
            ++G  G  G  GP GP   RG+PG +G     GP+G PG  G  G+PG PG  G +G  G
Sbjct: 322  EAGPTGPMGAMGPLGP---RGMPGERGR---LGPQGAPGQRGAHGMPGKPGPMGPLGIPG 375

Query: 831  KTGPPGPPGV---VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPG 887
             +G PG PG+    GP GA G  GP G+RG  GPPGP G  GLPG  G +GT G  GP G
Sbjct: 376  SSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTG 435

Query: 888  APGKDGPAGLRGFPGE------------RGLPGTAGGPGLKGNEGPSGPPGPAGSPGERG 935
            +PG  GP G  G PG             RG PG  G PG KG  GP G PGP G  G  G
Sbjct: 436  SPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIG 495

Query: 936  AAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAG 995
              G  G  GP G PG  GPPG  GE+G PG +G  G  G  G +G  G  GP G  G  G
Sbjct: 496  PPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKG 555

Query: 996  EDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGA---RGPQGHFG 1052
              GD G  G+PG  G +G  G  G  GP G +GP+G PG  G  G PG+   RG  G  G
Sbjct: 556  SQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMG 615

Query: 1053 AKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQG 1112
              G +G+ G  G PG  G  G+PG  G  G+ G+VGP GP GPPG  G  G  G  GP G
Sbjct: 616  LPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTG 675

Query: 1113 PPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT- 1171
              G  G  GPPGE G+PG+ G PG  G  G  GPRGERG  GE G+PG  G PG KG   
Sbjct: 676  FQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAG 735

Query: 1172 --GDDGPKGNPGPVGFPGDPGP------PGEGGPRGQDGAKGDRGEDGEP---------- 1213
              G DGPKG+PGP G PGD GP      PGE G  G  G KGDRG  GE           
Sbjct: 736  GHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDG 795

Query: 1214 --------GQPGSPGPTGENGPPGPLGKRGPAGS---PGSEGRQGGKGA----------- 1251
                    G PG  GPTGE G PGP G  GP GS   PGS G  G  GA           
Sbjct: 796  ARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDG 855

Query: 1252 ----KGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLP---GSVGQQGRPGATGQAGPPG 1304
                KG+PG  G  G  G  GP G AG PGP G  G+P   G  G QG PGATG  G  G
Sbjct: 856  QPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAG 915

Query: 1305 PVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPG 1364
             VGPPG  G  G AG  GE G  G  GL G PG  G  GDRG  GP G PG KG+ G  G
Sbjct: 916  RVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDG 975

Query: 1365 ASGPIGPGGP---------------------PGLPGPAGPKGAKGATGPGGPKGEKGVQG 1403
              GP GP GP                     PGLPGPAG  G  G TG  G KG  G  G
Sbjct: 976  QPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVG 1035

Query: 1404 PPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP-------TGGAPGSPG 1452
            PPG  GP GE     P        R  DG+   + D   P       + GAPG+PG
Sbjct: 1036 PPGSNGPVGEPGPEGPAGNDGTPGR--DGAVGERGDRGDPGPAGLPGSQGAPGTPG 1089


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 1103 bits (2852), Expect = 0.0
 Identities = 635/1411 (45%), Positives = 753/1411 (53%), Gaps = 111/1411 (7%)

Query: 314  PPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSG 373
            P  P  P    GP G +G+PGP G PG  G PG  G PGS G+PGPPG     P    +G
Sbjct: 92   PTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCP----TG 147

Query: 374  GGDKGPVVAAQEAQAQAIL-----QQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESG 428
              +  P   + + ++   +             GPPGP G +G PG  G PG  G  GE G
Sbjct: 148  PQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPG 207

Query: 429  DLGPQGPRGPQGLTGPPGKAGR---RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKG 485
              GP GP GP G  GP G AG+    GR G  G RG+PG PG+KG  G   +PG PG KG
Sbjct: 208  QAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAG---IPGFPGMKG 264

Query: 486  HRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDG 545
            HRG  G  G  G  G  G +G++G  G  G PG  GPRG  G +G PG+PG  G RG DG
Sbjct: 265  HRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDG 324

Query: 546  PQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPG 605
             +G  G  GP G PG  G  G+PG +G  GP G+ G +G  G +G+PG  G  G+ GPPG
Sbjct: 325  ARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPG 384

Query: 606  HPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIG 665
             PG  G PG KG  GP+G  G  G  G RG  G  G  G  G +G  GE G  G KG+ G
Sbjct: 385  PPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPG 444

Query: 666  VKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKG 725
             +G+RGE G+PG  G  G +G  G  G  G  G PG  GE+G          PG +GP G
Sbjct: 445  PRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGA---------PGFRGPAG 495

Query: 726  SLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHG 785
              G PG  G +GE+GA G +G  G  GE G  G  G  G RG  G  G  G+ G  GP G
Sbjct: 496  PNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPG 555

Query: 786  PPGERGLPGPQGPNG---FPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVG 842
              GE G PGP GP+G    PG  G PGP G DG PG  G+RG  G  G  GPPG  G  G
Sbjct: 556  SQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETG 615

Query: 843  PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPG------APGKDGPAG 896
            PQG  G TGP G++G  GPPGP G QGLPGT G  G  G PG PG      APG  G  G
Sbjct: 616  PQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKG 675

Query: 897  LRGFPGERGLPGTAGGPGLKGNEGPSGPPG---PAGSPGERGAAGSGGPIGPPGRPGPQG 953
              G PGERG PG AG PGL+G  GP GP G    AG PG  GAAG+ G  G PG  G  G
Sbjct: 676  DAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLG 735

Query: 954  PPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKG 1013
             PG  G+KG PG  G  G  G+DG +GP G   P GPPG AG+ GDKGE G PG  G  G
Sbjct: 736  SPGPKGDKGEPGGPGADGVPGKDGPRGPTG---PIGPPGPAGQPGDKGEGGAPGLPGIAG 792

Query: 1014 NKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQG 1073
             +G  G  G  GP GP G PGA G +GEPG +G +G  G KG+ G  G  GPPG  G  G
Sbjct: 793  PRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAG 852

Query: 1074 LPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESG 1133
             PGP G KGE G  G  G  G PG RG  GP G++G  GPPG  G+   PG+ G PG +G
Sbjct: 853  PPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGS---PGKDGPPGPAG 909

Query: 1134 SPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG 1193
            + G  G PGV GP      KG++GQPGE G PG +GP G  GP G  G  G  G  GPPG
Sbjct: 910  NTGAPGSPGVSGP------KGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPG 963

Query: 1194 EGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKG 1253
              GPRG  G +G +GE    G+PG+ G +GE GPPGP G  G AG+ G  GR G  G+ G
Sbjct: 964  MPGPRGSPGPQGVKGES---GKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDG 1020

Query: 1254 DPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG 1313
             PG  G+PG  G  G  G  G PG  G  G PG VG  G+ G  G++GP GP G PG  G
Sbjct: 1021 LPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAG 1080

Query: 1314 LRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSP---GQKGEMGIPGAS---G 1367
             RG  G +G +G  G  G  G  G +G +G  G PG  GSP   GQ+G +G PG +   G
Sbjct: 1081 SRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRG 1140

Query: 1368 PIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTR 1427
            P+GP GPPG  G +G  G  G  GP G +GE+G +G PGHPG PG    P P   P    
Sbjct: 1141 PVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPG---PPGPPGAPGPCC 1197

Query: 1428 RSVDGSRLMQEDEAIPTGGAP-------GSPGGLEEIFGSLDSLREEIEQMRRPTGTQDS 1480
              V  + +         G AP             +EI  SL S+  +IE +  P G++ +
Sbjct: 1198 GGVGAAAIAGIGGEKAGGFAPYYGDEPMDFKINTDEIMTSLKSVNGQIESLISPDGSRKN 1257

Query: 1481 PARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGETCVT------PR---- 1530
            PAR C+DLK CHPEL  GEYWVDPNQGC  DA +VFCN    GETC++      PR    
Sbjct: 1258 PARNCRDLKFCHPELKSGEYWVDPNQGCKLDAIKVFCNMET-GETCISANPLNVPRKHWW 1316

Query: 1531 ----------------DDVTQFSYVDSE-GSPVGVVQLTFLRLLSVSAHQDVSYPC---- 1569
                            D   QFSY + E    V  VQL FLRLLS  A Q+++Y C    
Sbjct: 1317 TDSSAEKKHVWFGESMDGGFQFSYGNPELPEDVLDVQLAFLRLLSSRASQNITYHCKNSI 1376

Query: 1570 ------SGAARDGPLRLRGANEDELSPETSP--YVKEFRDGCQTQQG---RTVLEVRTPV 1618
                  SG  +   L+L G+NE E   E +         DGC    G   +TV E RT  
Sbjct: 1377 AYMDQASGNVKKA-LKLMGSNEGEFKAEGNSKFTYTVLEDGCTKHTGEWSKTVFEYRTRK 1435

Query: 1619 LEQLPVLDASFSDLGAPPRRGGVLLGPVCFM 1649
              +LP++D +  D+G P +  GV +GPVCF+
Sbjct: 1436 AVRLPIVDIAPYDIGGPDQEFGVDVGPVCFL 1466



 Score =  881 bits (2276), Expect = 0.0
 Identities = 518/1187 (43%), Positives = 585/1187 (49%), Gaps = 124/1187 (10%)

Query: 221  CEQKELECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESS 280
            C+ +EL+C       P+          PQ   +    P  Q PQ     PG         
Sbjct: 67   CDDQELDCPN-----PEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPG--------- 112

Query: 281  LLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVE---------------------------- 312
              PP     +G  G+ G+ G P    P  + E                            
Sbjct: 113  --PPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLA 170

Query: 313  GPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGS 372
            G PGP GP G  GPPG  G+PG  G PG +GPPG  G  G  G PGPPG           
Sbjct: 171  GYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAI--------- 221

Query: 373  GGGDKGPVVAAQEAQAQAILQQARLALRGPP---------------GPMGYTGRPGPLGQ 417
              G  GP  A ++ ++    +     L GPP               G  G+ GR G  G+
Sbjct: 222  --GPSGP--AGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGE 277

Query: 418  PGSPGLKGES---------GDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGV 468
             G+PGLKGE+         G +GP+G  G +G  G PG AG RG  GA G+ G PG PG 
Sbjct: 278  TGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGP 337

Query: 469  KGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGP 528
             G  GF G PG  GE G  G  G+ G PG  GE G +G  G  GP G PG +G  G  G 
Sbjct: 338  PGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGE 397

Query: 529  KGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 588
             GP GIPG PG+ G  GP GP G+ G  G  G  G+ G  G +G PGP+   G  GE G 
Sbjct: 398  MGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPR---GERGEAGI 454

Query: 589  QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH 648
             G PG  G  G DG PG PG  G PG  G +G  G +GP G  G  G KG  G RG  G 
Sbjct: 455  PGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGP 514

Query: 649  KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 708
             G +G  G PG  G  G  G RG  G PG  G DG  GP G  G +G PGPPG  G +G+
Sbjct: 515  AGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQ 574

Query: 709  LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 768
             GV G PG  G  G  G  G  G PG  G +G  G +G++GP+G  GPTGP G +G    
Sbjct: 575  PGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGD--- 631

Query: 769  TGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGF 828
            TG  G +G  G  G  GPPGE G PG  GP G  G  G PG  G  G PG  G  G  G 
Sbjct: 632  TGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGA 691

Query: 829  QGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGA 888
             G  G  GPPG  G +GAAG  GP G  G PG  G PGE+G  G+ G +G KG+PG PGA
Sbjct: 692  PGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGA 751

Query: 889  ---PGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPP---GPAGSPGERGAAGSGGP 942
               PGKDGP   RG  G  G PG AG PG KG  G  G P   GP GSPGERG  G  GP
Sbjct: 752  DGVPGKDGP---RGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGP 808

Query: 943  IGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGE 1002
             G PG PG  G PG  GE+G PGEKG  GP    GV GP G  GPAGPPG  G  G++G 
Sbjct: 809  AGFPGAPGQNGEPGGKGERGAPGEKGEGGP---PGVAGPPGGSGPAGPPGPQGVKGERGS 865

Query: 1003 VGDPGQKGTKGNKGEHGPPGP---PGPIGPVGQPGA---------AGADGEPGARGPQGH 1050
             G PG  G  G +G  GPPG    PGP GP G PG           GA G PG  GP+G 
Sbjct: 866  PGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGD 925

Query: 1051 FGAKGDEGTRGFNGP---PGPIGLQGLPGPSGEKGETGDVGPMGPPGP---------PGP 1098
             G  G++G+ G  GP   PGP+G+ G+ G  G  G  G  GP G PGP         PG 
Sbjct: 926  AGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGA 985

Query: 1099 RGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQ 1158
             G +G  G  GPQG PG  G  G PG  G PG  G PG  G PG KG RGE G  G  G 
Sbjct: 986  NGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGA 1045

Query: 1159 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGS 1218
            PG PGPPGP GP G  G +G  GP G  G PGP G  G  G  G +GD+GE GE G  G 
Sbjct: 1046 PGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGI 1105

Query: 1219 PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGP 1278
             G  G  G PG  G  GPAG  G+ G  G  G +G  G  G PGK G  G  GP G PGP
Sbjct: 1106 KGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGP 1165

Query: 1279 DGLRGLPGSVGQQGRPGATGQAGPPGPVGP-PGLPGLRGDAGAKGEK 1324
             G RG  GS G  G PG  G  GPPG  GP  G  G    AG  GEK
Sbjct: 1166 RGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEK 1212



 Score =  151 bits (381), Expect = 6e-36
 Identities = 108/303 (35%), Positives = 117/303 (38%), Gaps = 71/303 (23%)

Query: 1209 EDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVG 1268
            +D E   P    P GE     P     P   P  +G QG KG  G PG  G  G  G  G
Sbjct: 68   DDQELDCPNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPG 127

Query: 1269 PAGPAGKPGPDGL----------------------------------------------- 1281
              G  G PGP G+                                               
Sbjct: 128  QPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGT 187

Query: 1282 ---RGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGE 1338
                G PGS G QG PG  GQAGP GP GPPG  G  G AG  GE G PG  G  G PG 
Sbjct: 188  SGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGP 247

Query: 1339 QGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGE 1398
             G KG  G+P   G PG KG  G  G +G  G  G PGL G  G  G  GA GP GP+G 
Sbjct: 248  PGIKGPAGIP---GFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGA 304

Query: 1399 KGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP----TGGAPGSPGGL 1454
             G +G PG PG  G               R  DG+R        P    T G PGSPG  
Sbjct: 305  PGERGRPGLPGAAG--------------ARGNDGARGSDGQPGPPGPPGTAGFPGSPGAK 350

Query: 1455 EEI 1457
             E+
Sbjct: 351  GEV 353


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 1023 bits (2645), Expect = 0.0
 Identities = 606/1393 (43%), Positives = 703/1393 (50%), Gaps = 121/1393 (8%)

Query: 318  EGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDK 377
            +GPAG  GP G +G PGP G  GE GP G    PG  G PGPPG       ++   G   
Sbjct: 32   KGPAGDRGPRGERGPPGPPGRDGEDGPTGP---PGPPGPPGPPGLGGNFAAQYDGKGVGL 88

Query: 378  GPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRG 437
            GP                 + L GP GP G  G PGP G  G  G  GE G  GP G RG
Sbjct: 89   GP---------------GPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARG 133

Query: 438  PQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPG 497
            P    GPPGKAG  G  G  G  G  G  G +G RGF G PGLPG KG RG  G  GL G
Sbjct: 134  P---AGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKG 190

Query: 498  PPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQG 557
             PG  G +G+ G  G  G PG++G RGL G +G  G PGP G RG DG  GP G  GP G
Sbjct: 191  QPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIG 250

Query: 558  EPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKG 617
              GPPG  G PG +G  G  G  GP G  GP+G+ GLPG+ G  GPPG+PG  G  G KG
Sbjct: 251  SAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKG 310

Query: 618  NQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV-- 675
              G  G  G  G PGPRG+ G  G  G  G +G  GE G  G KG+ G KG+ G  G   
Sbjct: 311  AAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQG 370

Query: 676  -PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPG 734
             PG  GE+G  GP G  G  G PGPPGL G  G  G+PG  G  G  GP GS G  G  G
Sbjct: 371  PPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAG 430

Query: 735  ASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPG 794
              G  G  G  G+ G  G RG  G  G  GP G  G  G  G  G  GP GP G RG P 
Sbjct: 431  VRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEP- 489

Query: 795  PQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMG 854
              G  GFPGPKGP G PGK+G  GH       G  G  G PGP G  G QG  G  G  G
Sbjct: 490  --GNIGFPGPKGPTGDPGKNGDKGH------AGLAGARGAPGPDGNNGAQGPPGPQGVQG 541

Query: 855  ERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPP------GAPGKDGPAGLRGFPGERGLPG 908
             +G  GPPGPPG QGLPG +G  G  G PG        G PG  GP G RG PGE G  G
Sbjct: 542  GKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAG 601

Query: 909  TAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP---PGAAGEKGVPG 965
              G  G +G  GP GP G  G PG  GA G+ GP GP G PG +G    PG  GEKG PG
Sbjct: 602  PTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPG 661

Query: 966  EKGPIGPTGRDGVQ---GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPG 1022
             +G IG  GRDG +   G VG PGPAG  G  GE G  G  G  G +G+ G +GE GP G
Sbjct: 662  LRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAG 721

Query: 1023 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKG 1082
            P G  GP G  G  GA GE GA+GP+G  G  G  G  G  GP GP    G PGP+G +G
Sbjct: 722  PNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGP---NGPPGPAGSRG 778

Query: 1083 ETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN---LGPPGEKGEPGESGSPGIQG 1139
            + G  G  G PG  G  GP GP+G  GP GPPG  G     GP G++G  G +G  G  G
Sbjct: 779  DGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVG 838

Query: 1140 EPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRG 1199
             PG  G +G  GE G +G PG PGP G  G  G  G  G+ G  G PG  G  GE GP G
Sbjct: 839  PPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLG 898

Query: 1200 QDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIG 1259
              G  G RG  G  G PG  G  GE G  G  G  GP G  G  G +G +G  G+ G +G
Sbjct: 899  IAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVG 958

Query: 1260 APGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAG 1319
            A G  GP GP GPAGK G  G  G  G VG  G  G  G +GP G  G  G PG +G  G
Sbjct: 959  AAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRG 1018

Query: 1320 AKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPG 1379
              G KGH GL GL   PG  G  GD+G PG  G  G +G  G  G +G  G  G PG  G
Sbjct: 1019 LPGLKGHNGLQGL---PGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVG 1075

Query: 1380 PAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQED 1439
            PAG +G +G  GP GP       GPPG PGPPG                   G      D
Sbjct: 1076 PAGIRGPQGHQGPAGP------PGPPGPPGPPG----------------VSGGGYDFGYD 1113

Query: 1440 EAIPTGGAPGSPGGLE----EIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPEL 1495
                    P S   L     E+  +L SL  +IE +  P G++ +PARTC+DL+L HPE 
Sbjct: 1114 GDFYRADQPRSAPSLRPKDYEVDATLKSLNNQIETLLTPEGSRKNPARTCRDLRLSHPEW 1173

Query: 1496 PDGEYWVDPNQGCARDAFRVFCNFTAGGETCVTPRDD----------------------- 1532
              G YW+DPNQGC  DA +V+C+F+  GETC+  + +                       
Sbjct: 1174 SSGYYWIDPNQGCTMDAIKVYCDFST-GETCIRAQPENIPAKNWYRSSKDKKHVWLGETI 1232

Query: 1533 --VTQFSY-VDSEGSPVGVVQLTFLRLLSVSAHQDVSYPCSGA-----ARDGPLR----L 1580
               +QF Y V+   S     QL F+RLL+  A Q+++Y C  +        G L+    L
Sbjct: 1233 NAGSQFEYNVEGVTSKEMATQLAFMRLLANYASQNITYHCKNSIAYMDEETGNLKKAVIL 1292

Query: 1581 RGANEDELSPETSP--YVKEFRDGCQ---TQQGRTVLEVRTPVLEQLPVLDASFSDLGAP 1635
            +G+N+ EL  E +         DGC     + G+T++E +T    +LP LD +  D+G  
Sbjct: 1293 QGSNDVELVAEGNSRFTYTVLVDGCSKKTNEWGKTIIEYKTNKPSRLPFLDIAPLDIGGA 1352

Query: 1636 PRRGGVLLGPVCF 1648
             +   V +GPVCF
Sbjct: 1353 DQEFFVDIGPVCF 1365



 Score =  761 bits (1966), Expect = 0.0
 Identities = 463/1034 (44%), Positives = 518/1034 (50%), Gaps = 123/1034 (11%)

Query: 283  PPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGER 342
            PP    A GP+G +G  GEP   EPG    GP G  GPAG  G  G  G+PG  G PGER
Sbjct: 101  PPGAAGAPGPQGFQGPAGEPG--EPGQT--GPAGARGPAGPPGKAGEDGHPGKPGRPGER 156

Query: 343  GPPGRAGLPGSDGAPGPPGTSLMLPFRFGSG--GGDKGPVVAAQEAQAQAILQQARLALR 400
            G  G  G  G  G PG PG   +       G  G    P V  +           +   R
Sbjct: 157  GVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGAR 216

Query: 401  GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGL---------------TGPP 445
            G PG  G  G PGP G  GS G  G  G  GP G  GP G                 GP 
Sbjct: 217  GLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPA 276

Query: 446  GKAGRRGRAGADGARGM---PGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGP---P 499
            G AG RG  G  G  G    PG+PG  G  G  G  GLPG  G  G  G +G+PGP    
Sbjct: 277  GPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAA 336

Query: 500  GEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEP 559
            G  G RG  GE GP G  GESG +G  G  GP G PGP G  G  GP G  GS GP   P
Sbjct: 337  GATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGP---P 393

Query: 560  GPPGQQGTPGTQGLPGPQG---AIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGP---P 613
            GPPG +G+PG++GLPG  G    +GP G +G  G  G+ G  G  G PG PG  GP   P
Sbjct: 394  GPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLP 453

Query: 614  GTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKG---DIGVKGDR 670
            G+ GN GP+G +GP+G PG   + G  G  G  G +GE G  GFPG KG   D G  GD+
Sbjct: 454  GSPGNIGPAGKEGPVGLPG---IDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDK 510

Query: 671  GEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFP 730
            G  G+ G+RG  GP+G  G  GP   PGP G+ G KG+ G PG PG+ G  GP G  G  
Sbjct: 511  GHAGLAGARGAPGPDGNNGAQGP---PGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEV 567

Query: 731  GFPGASGEKGARGLSGKSGPRGERGP---------TGPRGQRGPRGATGKSGAKG----- 776
            G PG  G  G  GL G +GPRGERGP         TGP G RGP G  G  G KG     
Sbjct: 568  GKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVV 627

Query: 777  ----TSGGDGPHGPPGERG---LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQ------- 822
                T+G  GP G PGERG   +PG +G  G PG +G  G PG+DG  G PG        
Sbjct: 628  GAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPA 687

Query: 823  --------------------RGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 862
                                RG  G +G+ GP GP G  GP GAAG+ G  GERG  GP 
Sbjct: 688  GATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPK 747

Query: 863  GPPG---EQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNE 919
            G  G     G  G AG  G  G PGP G+ G  GP G+ GFPG  G     G PG  G  
Sbjct: 748  GENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAG---RTGPPGPSGIS 804

Query: 920  GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 979
            GP GPPGPAG  G RG  G  GP+G  G  G  GPPG AGEKG  GE G  GP G  G Q
Sbjct: 805  GPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQ 864

Query: 980  GPVGLPGPAGPPGVAGE---DGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAA 1036
            G +G PG  G PG  GE    G  G VG+PG  G  G  G  GPPG  G  G  G PG A
Sbjct: 865  GLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEA 924

Query: 1037 GADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSG---------EKGETGDV 1087
            G DG PG  GP G  G  G +G RG+ G  GP+G  G PGP G          +GETG  
Sbjct: 925  GRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPS 984

Query: 1088 GPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGI------QGEP 1141
            GP+GP G  GPRGP+GP G  G +G PG  G  G PG KG  G  G PGI      QG P
Sbjct: 985  GPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAP 1044

Query: 1142 GVKGPRGERGEKGESG---QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPR 1198
            G  GP G RG  G SG   + G  G PG  GP G  GP+G+ GP G PG PGPP   GP 
Sbjct: 1045 GSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPP---GPP 1101

Query: 1199 GQDGAKGDRGEDGE 1212
            G  G   D G DG+
Sbjct: 1102 GVSGGGYDFGYDGD 1115



 Score =  600 bits (1546), Expect = e-171
 Identities = 342/728 (46%), Positives = 382/728 (52%), Gaps = 70/728 (9%)

Query: 747  KSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGP-------------------P 787
            + GP G+RGP G RG  GP G  G+ G  G  G  GP GP                   P
Sbjct: 31   RKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGP 90

Query: 788  GERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP------PGVV 841
            G  GL GP+GP G  G  GP G  G  G PG PGQ G  G +G  GPPG       PG  
Sbjct: 91   GPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKP 150

Query: 842  GPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP------GPPGAPGKD--- 892
            G  G  G  GP G RG PG PG PG +G+ G  G +G KG P      G PGAPG++   
Sbjct: 151  GRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTP 210

Query: 893  GPAGLRGFPGER---GLPGTAGGPGLKGNEGPSGPPGP---AGSPGERGAAGSGGPIGPP 946
            G  G RG PGER   G PG AG  G  G+ GP GP GP   AG PG  GA G  G IG  
Sbjct: 211  GQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAV 270

Query: 947  GRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP 1006
            G  GP GP G  GE G+PG  GP+GP G  G  G  G  G AG PGVAG  G  G  G P
Sbjct: 271  GNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIP 330

Query: 1007 GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFN--- 1063
            G  G  G  G  G  G P   GP G  G +G  GEPG+ GPQG  G  G+EG RG N   
Sbjct: 331  GPVGAAGATGARGLVGEP---GPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEA 387

Query: 1064 ---GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNL 1120
               GPPGP GL+G PG  G  G  G  G MGPPG  G  GPAG  G +G  G PG  G +
Sbjct: 388  GSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLM 447

Query: 1121 GPPGEKGEPGESGSPGIQGE---PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGD---D 1174
            GP G  G PG  G  G +G    PG+ G  G  G  G  G+PG  G PGPKGPTGD   +
Sbjct: 448  GPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKN 507

Query: 1175 GPKGNPGPVGFPGDPGPPGEG------GPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPP 1228
            G KG+ G  G  G PGP G        GP+G  G KG++G  G PG  G PGP+G  G  
Sbjct: 508  GDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEV 567

Query: 1229 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1288
            G  G+RG  G  G  G  G +G +G PG  GA G TGP+G  GP+G PGPDG +G PG V
Sbjct: 568  GKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVV 627

Query: 1289 GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDR--- 1345
                  GA G AGP GP G PG  G  G  G KGEKG PGL G IG PG  G +G     
Sbjct: 628  ------GAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAV 681

Query: 1346 GLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPP 1405
            G PGP G+ G +GE G  G +GP GP G PG  G  GP G  G  GP G  G+ G +G  
Sbjct: 682  GAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGER 741

Query: 1406 GHPGPPGE 1413
            G  GP GE
Sbjct: 742  GAKGPKGE 749



 Score =  303 bits (776), Expect = 9e-82
 Identities = 191/480 (39%), Positives = 215/480 (44%), Gaps = 107/480 (22%)

Query: 1072 QGLPGPSGEKGETGDVGPMGPPGPPGP------RGPAGPNGADGPQGPPGGVGNL----- 1120
            Q L   +  KG  GD GP G  GPPGP       GP GP G  GP GPPG  GN      
Sbjct: 23   QSLQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYD 82

Query: 1121 -----------------GPPGEKGEP---------GESGSPGIQGEPGVKGPRGERGEKG 1154
                             GPPG  G P         GE G PG  G  G +GP G  G+ G
Sbjct: 83   GKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAG 142

Query: 1155 ESGQPGEPGPPGPKGPTGD------------------------DGPKGNPGPVGFPGDPG 1190
            E G PG+PG PG +G  G                         DG KG PG  G  G+PG
Sbjct: 143  EDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPG 202

Query: 1191 PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKG 1250
             PGE G  GQ GA+G  GE G  G PG  G  G +G  GP+G  GP GS G  G  G  G
Sbjct: 203  APGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPG 262

Query: 1251 AKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPG 1310
             KG+ GA+G  G  GP GP G  G PG  G  G PG+ G  G  GA G AG PG  G PG
Sbjct: 263  PKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPG 322

Query: 1311 LPGLR---------------------GDAGAKGE---KGHPGLIGLIGPPGEQGEKGDR- 1345
            LPG R                     G AG+KGE   KG PG  G  GPPG  GE+G R 
Sbjct: 323  LPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRG 382

Query: 1346 --------GLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKG 1397
                    G PGP G  G  G  G+PGA G  G  GPPG  G +GP G +G  G  G  G
Sbjct: 383  PNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPG 442

Query: 1398 EKGVQGPPGHPGPPGEV---IQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGL 1454
            E G+ GP G PG PG +    +  P+ +P      +DG         I   GA G PG +
Sbjct: 443  EPGLMGPRGLPGSPGNIGPAGKEGPVGLP-----GIDG-----RPGPIGPAGARGEPGNI 492


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  991 bits (2562), Expect = 0.0
 Identities = 597/1336 (44%), Positives = 677/1336 (50%), Gaps = 214/1336 (16%)

Query: 291  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 350
            GP G+ G KGEP      +++   PGP+G  G  GPPGIQG PGP G PG  GPPG  GL
Sbjct: 147  GPPGIPGMKGEPG----SIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGL 202

Query: 351  PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYT- 409
             G  G PG PG    +   F    G+KG                    L+GPPGP G   
Sbjct: 203  MGPPGPPGLPGPKGNMGLNFQGPKGEKG-----------------EQGLQGPPGPPGQIS 245

Query: 410  ---------------GRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRA 454
                           G PG  G PG PG++G  G   P G +G +G  G PGK   RG+ 
Sbjct: 246  EQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGP--PGGEKGEKGEQGEPGK---RGKP 300

Query: 455  GADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPG----PPGEDGERGDDGE 510
            G DG  G PG PG+ GD G+ G PG  GEKG +GDTG  G PG     PG     G+ G 
Sbjct: 301  GKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGN 360

Query: 511  IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGE-----------P 559
            IG  GLPGE G RG  G +GPPG+PGPPG   M GP GP G  G +G+           P
Sbjct: 361  IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM-GPPGPPGFPGERGQKGDEGPPGISIP 419

Query: 560  GPPGQQGTPGTQGLPGPQGAIGPH-------GEKGPQGKPGLPG---------------- 596
            GPPG  G PG  GLPGP G  GPH        E GP G PG PG                
Sbjct: 420  GPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGD 479

Query: 597  ---------MPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKG 647
                     + G  G PG PG  GPPG+ G  G  G +G  G  GP+G+ G+ G  G  G
Sbjct: 480  TCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPG 539

Query: 648  HKGEKGEDG----FPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLM 703
              G KGE G    FPG KGD G  G  G  G+PG  G  G +G  G  GP G+PG     
Sbjct: 540  FPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFK 599

Query: 704  GEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQR 763
            GE+G  G PGLPG PG  GP G  GF G PG  GEKG +G++G  G  G  GP G  GQ 
Sbjct: 600  GERGPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQT 658

Query: 764  GPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKG-----------PPGPPG 812
              +   GK G  G  G DG  G PG+ GLPG  G  G PG KG           PPGP G
Sbjct: 659  ITQ--PGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKG 716

Query: 813  KDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAG-----------------ETGPMGE 855
              G+PG PG  G  G  G  GPPGPPG  GP+G  G                   GP G+
Sbjct: 717  FPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGD 776

Query: 856  RGHPGPPGPPGE---QGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGG 912
            RG PGPPGPPG     GLPG  G  G  G PGP G PG  G  G++G PG  G+PG  G 
Sbjct: 777  RGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG-IGVQGPPGPPGIPGPIGQ 835

Query: 913  PGLKGNEGPSGPPGPAG-----SPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEK 967
            PGL G  G  G PGP G      PGERG+ G  G  GP G PG  G PG AG  G PG K
Sbjct: 836  PGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTK 895

Query: 968  GPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPI 1027
            G +G  G  G  GP+G+PG +G PG+ G+DG +G+ G PG  G KG+KGE G PGPPGP+
Sbjct: 896  GEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPM 955

Query: 1028 GP-----VGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNG------PPGPIGLQGLPG 1076
             P      G+ G  G  G PG  GP+G+ G  GD G  G +G      PPGP G  GLPG
Sbjct: 956  DPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPG 1015

Query: 1077 PSG---EKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG-----------GVGNLGP 1122
              G     G  G +G MG PGP G  GP GP+G  G  G PG           G+ ++G 
Sbjct: 1016 QPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGL 1075

Query: 1123 PGEKGEPGESGSPGIQGEPGVKGPRGERG---------EKGESGQPGEPGPPGPKGPTGD 1173
            PG  G  GE G PG  G PG+KG  G+ G          KG+ G PG PG PGP GP G 
Sbjct: 1076 PGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGI 1135

Query: 1174 DGPKGNPG------PVG---FPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGE 1224
             GP GNPG      PVG    PG PGPPGE G  GQDG  G  G+ GEPGQPG   P G 
Sbjct: 1136 SGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNP-GP 1194

Query: 1225 NGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGL 1284
             G PG  G++G  G PG  G  G  G KG+PG  G PG  GP GP G  G P  +G +G 
Sbjct: 1195 PGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGN 1253

Query: 1285 PGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL------IGPPGE 1338
            PG  G  GRPG TG  G PGP GPPGLPG  G  G KG  G PGL GL       GPPG 
Sbjct: 1254 PGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL 1313

Query: 1339 QGE---------KGDRGLPGPQGSPGQKGEMGIPGASGP------IGPGGPPGLPGPAGP 1383
            QG          KGD GLPG  G PG KG  G+PG++GP      IGP GPPGLPGP+G 
Sbjct: 1314 QGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQ 1373

Query: 1384 K-------GAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLM 1436
                    G  G  G  G KG  G QGP G PGP G    P    +P       DG+   
Sbjct: 1374 SIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP-----GFDGAGGR 1428

Query: 1437 QEDEAIPTGGAPGSPG 1452
            + D  +P  G PG+ G
Sbjct: 1429 KGDPGLP--GQPGTRG 1442



 Score =  884 bits (2283), Expect = 0.0
 Identities = 551/1263 (43%), Positives = 634/1263 (50%), Gaps = 187/1263 (14%)

Query: 291  GPRGLKGEKGEPAVLEPGMLVEGPPGP-------------------EGPAGLIGPPGIQG 331
            GP+G KGE+G          ++GPPGP                   +G  G  GPPG  G
Sbjct: 224  GPKGEKGEQG----------LQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273

Query: 332  NPGPVGDP-------GERGPPGRAGLPGSDGAPGPPGTSLM--------LPFRFGSGG-- 374
              GP G P       GE+G PG+ G PG DG  G PG   +         P R G  G  
Sbjct: 274  IRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQK 333

Query: 375  GDKGP-----VVAAQEAQAQAILQQARLAL---------RGPPGPMGYTGRPGP-----L 415
            GD GP     +V  +      I ++  + L         RG PG  G  G PGP     +
Sbjct: 334  GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM 393

Query: 416  GQPGSPGLKGESGDLGPQGP-----RGPQGLTGPPGKAGRRGRAGADGAR---------- 460
            G PG PG  GE G  G +GP      GP GL G PG  G  G  G  G            
Sbjct: 394  GPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEP 453

Query: 461  GMPGDPGVKGDRGFDGLPGLPGEKGH----------RGDTGAQGLPGPPGEDGERGDDGE 510
            G PG PG  GD+G  G  G+ G+KG            G  G  GLPG PG  G  G  G+
Sbjct: 454  GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQ 513

Query: 511  IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRG-------MDGPQGPKGSLGPQGEPGPPG 563
             G +G  G +GP+GL G  G PG PG PG +G         G +G KG LG  G PG PG
Sbjct: 514  KGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573

Query: 564  QQGTPGTQGLPGPQGAIGP------HGEKGPQGKPGLPGMPGSDGPPGHP--GKEGPPGT 615
              GTPG  GLPG  G  G        GE+GP G PGLPG+PG+ GP G P  G  GP G 
Sbjct: 574  LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGE 633

Query: 616  KGNQGPSGPQGPLGYPGPRGVKGVDGIR-GLKGHKGEKGEDGFPGFKGDIGVKGDRGEVG 674
            KG QG +G  G  G PGP+G  G    + G  G  G  G DG  G  GD G+ G  G  G
Sbjct: 634  KGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPG 693

Query: 675  VPGSRGE--------DGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQ----- 721
            +PGS+GE         GP GPKG  G  G PG PG  G  G  G PG PG+PG +     
Sbjct: 694  IPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF 753

Query: 722  ---GPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTS 778
               GP G  G PGF GA G KG RG  G  GP G  G  G  G +G  G  G+ G  G  
Sbjct: 754  ALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPP 813

Query: 779  G--GDGPHGPPGERGLPGP---QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGF---QG 830
            G  G G  GPPG  G+PGP    G +G PG KG PGPPG D +PG PG+RG  G     G
Sbjct: 814  GLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLD-VPGPPGERGSPGIPGAPG 872

Query: 831  KTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG 890
              GPPG PG+ G  GA+G  G  GE G  GPPGPPG  G+PG +G  G KGD G  G PG
Sbjct: 873  PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPG 932

Query: 891  KDGPAGLRGFPGERGLPGTAG--GPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGR 948
              GP G +G  GE GLPG  G   P L G++G  G PG  G PG  G  G  G  G PG+
Sbjct: 933  LPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQ 992

Query: 949  PGPQ------GPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGP---AGPPGVAGEDGD 999
            PG        GPPG  G  G+PG+ G IGP G  G  G +G PGP    GPPG +G  G 
Sbjct: 993  PGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQ 1052

Query: 1000 KGEVGDPGQKGTKGNKGEH--------GPPGPPGPIGPVGQPGAAGADGEPGARGPQGHF 1051
             G  G PGQKG KG+ G          GP G PG  G  G PG  G+ G+PG  G  G  
Sbjct: 1053 PGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTP 1112

Query: 1052 GAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPM------GPPGPPGPRGPAGPN 1105
            GAKG  G  GF G PGP G +G+ GP G  G  G+ GP+      G PGPPG +G  G +
Sbjct: 1113 GAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQD 1172

Query: 1106 GADGPQGPPG-----GVGNLGP---PGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESG 1157
            G  GP G  G     G GN GP   PG  G+ G+ G PGI G PG+ GP+GE G  G  G
Sbjct: 1173 GIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPG 1232

Query: 1158 QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGP------PGEGGPRGQDGAKGDRGEDG 1211
              G PGPPG  GP   +GPKGNPGP G PG PGP      PG  GP G  G  G +GE G
Sbjct: 1233 VQGPPGPPGSPGP-ALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKG 1291

Query: 1212 EPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAG 1271
             PGQPG P      G PG  G +GP G  G+ GR G  G KGDPG  G PG  G  GP+G
Sbjct: 1292 NPGQPGLP------GLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSG 1345

Query: 1272 PAGKPGPDGLRGLPGSVGQQGRPGATGQA----GPPGPVGPPGLPGLRGDAGAKGEKGHP 1327
              G  GP+G  GL G  G  G PG +GQ+    G  GP G PG PGL+G  G +G +G P
Sbjct: 1346 VPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLP 1405

Query: 1328 GLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAK 1387
                  GP G  G+ G  GLPG  G+ G+KG+ G+PG  G  G  GPPG  G  GP G  
Sbjct: 1406 ------GPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPP 1459

Query: 1388 GAT 1390
            G +
Sbjct: 1460 GTS 1462



 Score =  878 bits (2268), Expect = 0.0
 Identities = 544/1236 (44%), Positives = 622/1236 (50%), Gaps = 163/1236 (13%)

Query: 270  PGEEEEILESSLLPPLE-EAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPG 328
            PG   +I E     P++ E   G +GL G++G P    PG  + GPPGP  P G  G  G
Sbjct: 238  PGPPGQISEQKR--PIDVEFQKGDQGLPGDRGPPG--PPG--IRGPPGP--PGGEKGEKG 289

Query: 329  IQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--GDKGP-----VV 381
             QG PG  G PG+ G  G+ G+PG  G PG PG     P R G  G  GD GP     +V
Sbjct: 290  EQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGE----PGRDGEKGQKGDTGPPGPPGLV 345

Query: 382  AAQEAQAQAILQQARLAL---------RGPPGPMGYTGRPGP-----LGQPGSPGLKGES 427
              +      I ++  + L         RG PG  G  G PGP     +G PG PG  GE 
Sbjct: 346  IPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGER 405

Query: 428  GDLGPQGPRG-----PQGLTGPPGKAGRRGRAGADGAR----------GMPGDPGVKGDR 472
            G  G +GP G     P GL G PG  G  G  G  G            G PG PG  GD+
Sbjct: 406  GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDK 465

Query: 473  GFDGLPGLPGEKGHR----------GDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGP 522
            G  G  G+ G+KG            G  G  GLPG PG  G  G  G+ G +G  G +GP
Sbjct: 466  GLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGP 525

Query: 523  RGLLGPKGPPGIPGPPGVRG-------MDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG 575
            +GL G  G PG PG PG +G         G +G KG LG  G PG PG  GTPG  GLPG
Sbjct: 526  KGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPG 585

Query: 576  PQGAIGP------HGEKGPQGKPGLPGMPGSDGPPGHPG--KEGPPGTKGNQGPSGPQGP 627
              G  G        GE+GP G PGLPG+PG+ GP G PG    GP G KG QG +G  G 
Sbjct: 586  LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQ 645

Query: 628  LGYPGPRGVKGVDGIR-GLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDG--- 683
             G PGP+G  G    + G  G  G  G DG  G  GD G+ G  G  G+PGS+GE G   
Sbjct: 646  PGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPG 705

Query: 684  -----PEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQG--------PKGSLGFP 730
                 P GPKG  G  G PG PG  G  G  G PG PG+PG +G        P G  G P
Sbjct: 706  IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLP 765

Query: 731  GFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSG--GDGPHGPPG 788
            GF GA G KG RG  G  GP G  G  G  G +G  G  G+ G  G  G  G G  GPPG
Sbjct: 766  GFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPG 825

Query: 789  ERGLPGPQGP---NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGP---PGPPGVVG 842
              G+PGP G    +G PG KG PGPPG D +PG PG+RG  G  G  GP   PG PG+ G
Sbjct: 826  PPGIPGPIGQPGLHGIPGEKGDPGPPGLD-VPGPPGERGSPGIPGAPGPIGPPGSPGLPG 884

Query: 843  PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG 902
              GA+G  G  GE G  GPPGPPG  G+PG +G  G KGD G  G PG  GP G +G  G
Sbjct: 885  KAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKG 944

Query: 903  ERGLPGTAG--GPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQG------P 954
            E GLPG  G   P L G++G  G PG  G PG  G  G  G  G PG+PG  G      P
Sbjct: 945  EPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGP 1004

Query: 955  PGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAG---PPGVAGEDGDKGEVGDPGQKGT 1011
            PG  G  G+PG+ G IGP G  G  G +G PGP G   PPG +G  G  G  G PGQKG 
Sbjct: 1005 PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064

Query: 1012 KGNKGEH--------GPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFN 1063
            KG+ G          GP G PG  G  G PG  G+ G+PG  G  G  GAKG  G  GF 
Sbjct: 1065 KGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP 1124

Query: 1064 GPPGPIGLQGLPGPSGEKGETGDVGPMG------PPGPPGPRGPAGPNGADGPQGPPG-- 1115
            G PGP G +G+ GP G  G  G+ GP+G       PGPPG +G  G +G  GP G  G  
Sbjct: 1125 GTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEP 1184

Query: 1116 ---GVGNLGPPGE---KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPG--- 1166
               G GN GPPG     G+ G+ G PGI G PG+ GP+GE G  G  G  G PGPPG   
Sbjct: 1185 GQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG 1244

Query: 1167 -----PKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGP 1221
                 PKG  G  GP G PGP GF G PGP G  G  G  G KG++G  G+PG PG PG 
Sbjct: 1245 PALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1304

Query: 1222 TGENGPPGPLGK---------RGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGP 1272
             G+ GPPG  G          +G  G PG  G  G KG  G PG+ G  G+ G +GP GP
Sbjct: 1305 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1364

Query: 1273 AGKPGPDGLR----------GLPGSVGQQGRPGATGQAGPPGPVGPPGLP---GLRGDAG 1319
             G PGP G            G+PG  G +G PG  G  G PGP GPPG P   GL G  G
Sbjct: 1365 PGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDG 1424

Query: 1320 AKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPG 1355
            A G KG PGL G  G  G  G  G  GL GP G PG
Sbjct: 1425 AGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460



 Score =  819 bits (2115), Expect = 0.0
 Identities = 491/1070 (45%), Positives = 556/1070 (51%), Gaps = 115/1070 (10%)

Query: 467  GVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLL 526
            G+KG++G  G PGL   +GH G  G  G  GPPG  G++GDDG      +PG  GP+G+ 
Sbjct: 42   GIKGEKGERGFPGL---EGHPGLPGFPGPEGPPGPRGQKGDDG------IPGPPGPKGIR 92

Query: 527  GPKGPPGIPGPPGVRGM------DGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAI 580
            GP G PG PG PG+ GM       GPQG  G  G +GE G PG  G PG QG PGP G  
Sbjct: 93   GPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIP 152

Query: 581  GPHGE---------KGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYP 631
            G  GE          GP+G PG PG PG  G PG  G  GP G  G  G  GP GP G P
Sbjct: 153  GMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLP 212

Query: 632  GPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIG-------VKGDRGEVGVPGSRGEDGP 684
            GP+G  G++  +G KG KGE+G  G PG  G I        V+  +G+ G+PG R   GP
Sbjct: 213  GPKGNMGLN-FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDR---GP 268

Query: 685  EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 744
             GP G  GP G PG  G  GEKG+ G PG  G PG+ G  G  G PG PG  G  G  G 
Sbjct: 269  PGPPGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326

Query: 745  SGKSGPRGERGPTGPRGQRGPRGATGKS-GAKGTSGGDGPHGPPGERGLPGPQGPNGFPG 803
             G+ G +G+ GP GP G   PR  TG + G KG  G  G  G  GERG PG QGP G PG
Sbjct: 327  DGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPG 386

Query: 804  PKGPP--GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERG---- 857
            P G    GPPG  G PG  GQ+G+ G  G    PGPPG+ G  GA G  GP G  G    
Sbjct: 387  PPGAAVMGPPGPPGFPGERGQKGDEGPPG-ISIPGPPGLDGQPGAPGLPGPPGPAGPHIP 445

Query: 858  ------HPGPPGPPGEQGLPGTAGKEGTKGDPGPPG----APGKDGPAGLRGFPGERGLP 907
                   PGPPGPPG  G  G  G++G KGD G         G  GP G  G PG  G P
Sbjct: 446  PSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPP 505

Query: 908  GTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGP----QGPPGAAGEKGV 963
            G+ G PG KG +G +G  GP G PG  GA G+ G  G  G PG      G  G  GE G 
Sbjct: 506  GSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGS 565

Query: 964  PGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPP-- 1021
            PG  G  G  G  G  G  GLPGP G PG     G++G  G+PG  G  GN G  GPP  
Sbjct: 566  PGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF 625

Query: 1022 GPPGPIGPVGQPGAAGADGEPGARGPQGHFGA-------------KGDEGTRGFNGPPGP 1068
            GPPGP+G  G  G AG  G+PG  GP+G  G               G +G  G  G PG 
Sbjct: 626  GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGL 685

Query: 1069 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1128
             G  GLPG  G KGE G  G +G PGPPGP+G  G  G  G  G PG +G  GPPG  G 
Sbjct: 686  PGQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGF 744

Query: 1129 PGESGSPGI-----QGEPGVKGPRGERGEKGESGQPGEPGPPGP------KGPTGDDGPK 1177
            PG  G PG       G PG+ G +G  G KG+ G PG PGPPG        GP GD GP 
Sbjct: 745  PGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804

Query: 1178 GNPGPVGFP--------GDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG--SPGPTGENGP 1227
            G PGP+G P        G PGPPG  GP GQ G  G  GE G+PG PG   PGP GE G 
Sbjct: 805  GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGS 864

Query: 1228 PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGS 1287
            PG  G  GP G PGS G  G  GA G PG  G  G  GP GP GP G PG  G+ GL G 
Sbjct: 865  PGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924

Query: 1288 VGQQGRPGATGQAGPPGPVGPPGLPGLRGD-----AGAKGEKGHPGLIGLIGPPGEQGEK 1342
             G QG+PG  G  G  G  G PGLPG  G       G+KGEKG PGL G+   PG  G K
Sbjct: 925  DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGI---PGVSGPK 981

Query: 1343 GDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQ 1402
            G +GLPG  G PG  G+ G+PG  GP G  G PG PG  GP G KG  G  G  G +GV+
Sbjct: 982  GYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVE 1041

Query: 1403 GPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1452
            GPPG  G PG+   P            + G +  + D  I + G PG PG
Sbjct: 1042 GPPGPSGVPGQPGSP-----------GLPGQKGDKGDPGISSIGLPGLPG 1080



 Score =  778 bits (2010), Expect = 0.0
 Identities = 465/1038 (44%), Positives = 534/1038 (51%), Gaps = 117/1038 (11%)

Query: 284  PLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 343
            P ++   G +G+KG+KG+      G  + GPPG  G  GL GPPG  G PG  G+ G+ G
Sbjct: 462  PGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAG 521

Query: 344  PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKG-----PVVAAQEAQAQAILQQARLA 398
              G  GLPG  GAPG PG        F    G+ G     P +   + +  +        
Sbjct: 522  ATGPKGLPGIPGAPGAPG--------FPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573

Query: 399  LRGPPGPMGYTGRPGPLGQPG------------SPGLKGESGDLGPQGPRGPQGLTGPPG 446
            L G PG  G  G PGP G+PG            +PGL G  G++GP GP G     GPPG
Sbjct: 574  LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG----FGPPG 629

Query: 447  KAGRRGRAGADGARGMPGDPGVKGDRGFD----GLPGLPGEKGHRGDTGAQGLPGPPGED 502
              G +G  G  G  G PG PG KGD G      G PGLPG  G  GD G  G PG PG+ 
Sbjct: 630  PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689

Query: 503  GERGDDGEIGPRG-----LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQG 557
            G  G  G  G  G     LPG  GP+G  G  GPPG PG PG  G++GP GP G  GP+G
Sbjct: 690  GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG 749

Query: 558  EPG-----PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG---PPGHPGK 609
            EPG     PPG  G PG +G  GP+G  G  G  GP G+ GL G+PG  G   P G PG 
Sbjct: 750  EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGP 809

Query: 610  EGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGED--GFPGFKGDIGVK 667
             GPPG  G  G  GP GP G PGP G  G+ GI G KG  G  G D  G PG +G  G+ 
Sbjct: 810  MGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIP 868

Query: 668  GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL 727
            G  G +G PGS G  G  G  G  G  G+ G  G  G  G LG+PG  G PG +G  G  
Sbjct: 869  GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ 928

Query: 728  GFPGFPGASGEKGARGLSGKSGPRGERGPT--GPRGQRGPRGATGKSGAKGTSGGDGPHG 785
            G PG PG +GEKG++G  G  GP G   P   G +G++G  G  G  G  G  G  G  G
Sbjct: 929  GQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPG 988

Query: 786  PPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGF------QGKTGPPGPPG 839
             PG+ GL G  G  G PGPKG PG PG+ GL G PG +G +G       QG  GPPGP G
Sbjct: 989  DPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSG 1048

Query: 840  VVGPQGAAGETGPMGERGHPGP--------PGPPGEQGLPGTAGKEGTKGDPGPPGAPGK 891
            V G  G+ G  G  G++G PG         PGP GE GLPG  G  G KG  G PG PG 
Sbjct: 1049 VPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGL 1108

Query: 892  DGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGP 951
             G  G +G PG  G PGT G PG KG    SGPPG  G PGE G  G GG    PG+PGP
Sbjct: 1109 PGTPGAKGQPGLPGFPGTPGPPGPKGI---SGPPGNPGLPGEPGPVGGGGH---PGQPGP 1162

Query: 952  QGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGT 1011
             G  G  G+ G+PG  G  G  G+ G     G PGP G PG++G+ GD G  G PG  G 
Sbjct: 1163 PGEKGKPGQDGIPGPAGQKGEPGQPGF----GNPGPPGLPGLSGQKGDGGLPGIPGNPGL 1218

Query: 1012 KGNKGE---HGPPGPPGPIGPVGQPGAA--GADGEPGARGPQGHFGAKGDEGTRGFNGPP 1066
             G KGE   HG PG  GP GP G PG A  G  G PG +GP G        G  GF G P
Sbjct: 1219 PGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGR------PGPTGFQGLP 1272

Query: 1067 GPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEK 1126
            GP G  GLPG  G KGE G+ G  G PG PG +G          QGPPG  GN G PG  
Sbjct: 1273 GPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGD---------QGPPGLQGNPGRPGLN 1323

Query: 1127 GEPGESGSPGIQGEPGVKGPRGERGEKGESGQPG---EPGPPGPKGPTG-------DDGP 1176
            G  G+ G PG+ G PG+KGP G  G  G  G+PG    PGPPG  GP+G       D GP
Sbjct: 1324 GMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGP 1383

Query: 1177 KGNPG------------PVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGE 1224
             G PG            P G PG  GPPG+ G  G  G  G  G  G+PG PG PG  G 
Sbjct: 1384 PGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGL 1443

Query: 1225 NGPPGPLGKRGPAGSPGS 1242
            +GPPGP G +GP G PG+
Sbjct: 1444 DGPPGPDGLQGPPGPPGT 1461



 Score =  564 bits (1454), Expect = e-160
 Identities = 353/816 (43%), Positives = 402/816 (49%), Gaps = 152/816 (18%)

Query: 291  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPG---------IQGNPGPVGDPGE 341
            G  G+ G KGEP +  PG+ + GPPGP+G  G+ GPPG         ++G PGP G PG 
Sbjct: 690  GLPGIPGSKGEPGI--PGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGP 747

Query: 342  RG--------PPGRAGLPGSDGA---------PGPPGTSLMLPFRFGSGG--GDKGPVVA 382
            +G        PPG  GLPG  GA         PGPPG     P R G  G  G KG V  
Sbjct: 748  KGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGP----PGRTGLDGLPGPKGDVGP 803

Query: 383  AQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQG-------- 434
              +           + ++GPPGP G    PGP+GQPG  G+ GE GD GP G        
Sbjct: 804  NGQPGPMGPPGLPGIGVQGPPGPPGI---PGPIGQPGLHGIPGEKGDPGPPGLDVPGPPG 860

Query: 435  ------------PRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG--------------- 467
                        P GP G  G PGKAG  G  G  G  GM G PG               
Sbjct: 861  ERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPG 920

Query: 468  VKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED-----GERGDDGEIGPRGLPGESGP 522
            +KGD G  G PGLPG  G +G  G  GLPGPPG       G +G+ GE G  G+PG SGP
Sbjct: 921  LKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGP 980

Query: 523  RGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG---PPGQQGTPGTQGLPGPQGA 579
            +G  G  G PG PG  G  G+ GP GPKG+ G  G+PG   PPG +GT G  G PGPQG 
Sbjct: 981  KGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGV 1040

Query: 580  IGPHGEKG--------------------------------PQGKPGLPGMPG------SD 601
             GP G  G                                P+G+PGLPG PG      S 
Sbjct: 1041 EGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSV 1100

Query: 602  GPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFK 661
            G PG PG  G PG KG  G  G  G  G PGP+G+ G  G  GL G  G  G  G PG  
Sbjct: 1101 GDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQP 1160

Query: 662  GDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQ 721
            G  G KG  G+ G+PG  G+ G  G  G   P G PG PGL G+KG  G+PG+PG PG  
Sbjct: 1161 GPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNP-GPPGLPGLSGQKGDGGLPGIPGNPGLP 1219

Query: 722  GPKGSLGFPGFPGASGEKGARGLSGKS--GPRGERGPTGPRGQRGPRGATGKSGAKGTSG 779
            GPKG  GF GFPG  G  G  G  G +  GP+G  GP GP G+ GP G  G  G +G  G
Sbjct: 1220 GPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPG 1279

Query: 780  GDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPG 839
              G  G  GE+G PG  G  G PG KG  GPPG  G PG PG  G  G  G  G PG PG
Sbjct: 1280 LPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPG 1339

Query: 840  VVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT-KGDPGPPGAPGKDGPAGLR 898
            + GP G  G  GP GE G  GPPGPPG   LPG +G+    KGD GPPG PG+       
Sbjct: 1340 MKGPSGVPGSAGPEGEPGLIGPPGPPG---LPGPSGQSIIIKGDAGPPGIPGQ------- 1389

Query: 899  GFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAA 958
              PG +GLPG  G  GL G   P+GPPG  G  G  G  G+GG  G PG PG        
Sbjct: 1390 --PGLKGLPGPQGPQGLPG---PTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQ------- 1437

Query: 959  GEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA 994
                 PG +G  GP G DG+QGP   PGP G   VA
Sbjct: 1438 -----PGTRGLDGPPGPDGLQGP---PGPPGTSSVA 1465



 Score =  559 bits (1440), Expect = e-159
 Identities = 357/848 (42%), Positives = 405/848 (47%), Gaps = 159/848 (18%)

Query: 757  TGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL 816
            +G +G++G RG  G  G  G  G  GP GPPG RG  G  G  G PGPKG  GPP   GL
Sbjct: 41   SGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPP---GL 97

Query: 817  PGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGK 876
            PG PG  G  G  G  G PGP G+ G  G  GE G  G  G PG  GPPG  G+PG  G+
Sbjct: 98   PGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGE 157

Query: 877  EGT---KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP---PGPAGS 930
             G+      PGP G PG  GP G++G PG  G+PG  G PG  G  GP GP   PGP G+
Sbjct: 158  PGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGN 217

Query: 931  --------PGERGAAGSGGPIGPPGR-------------------PGPQGPPGAAGEKGV 963
                     GE+G  G  GP GPPG+                   PG +GPPG  G +G 
Sbjct: 218  MGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP 277

Query: 964  P----GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHG 1019
            P    GEKG  G  G  G +G  G  G  G PG+ G  GD G  G+PG+ G KG KG+ G
Sbjct: 278  PGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTG 337

Query: 1020 PPGPPGPI-------------GPVGQPGAAGADGE---------------PGA--RGPQG 1049
            PPGPPG +             G +G PG  G  GE               PGA   GP G
Sbjct: 338  PPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG 397

Query: 1050 HFGAKGDEGTRGFNGP-----PGPIGLQGLPGPSGEKGETGDVGPMGP-------PGPPG 1097
              G  G+ G +G  GP     PGP GL G PG  G  G  G  GP  P       PGPPG
Sbjct: 398  PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG 457

Query: 1098 PRGPAGPNGADGPQGPPG----------GVGNLGPPGEKGEPGESGSPGIQGEPGVKGPR 1147
            P G  G  G  G QG  G          G G  GPPG+ G PG  G PG  G PG KG +
Sbjct: 458  PPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEK 517

Query: 1148 GERGEKGESGQPGEPGPPGP----------------KGPTGDDGPKGNPGPVGFPGDPGP 1191
            G+ G  G  G PG PG PG                  G  GD G  G+PG  G PG PG 
Sbjct: 518  GQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT 577

Query: 1192 PGEG------GPRGQDGA---KGDRGEDGEPGQPGSPGPTGEN-----GPPGPLGKRGPA 1237
            PG+       GP+G+ G    KG+RG  G PG PG PG  G       GPPGP+G++G  
Sbjct: 578  PGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQ 637

Query: 1238 GSPGSEGRQGGKGAKGDPGAI----------GAPGKTGPVGPAGPAGKPGPDGLRGLPGS 1287
            G  G+ G+ G  G KGDPG            G PG+ G VG  G  G PG  GL G+PGS
Sbjct: 638  GVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGS 697

Query: 1288 VGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRG- 1346
             G+ G PG     G PGP GP G PG+ G  GA G  G  GL G  GPPG  G KG+ G 
Sbjct: 698  KGEPGIPG----IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF 753

Query: 1347 -LPGPQGSP---------GQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPK 1396
             LPGP G P         G KG+ G PG  GP G  G  GLPGP G  G  G  GP GP 
Sbjct: 754  ALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPP 813

Query: 1397 GEK--GVQGPPGHPGPPGEVIQP----LPIQM--PKKTRRSVDGSRLMQEDEAIPTG--- 1445
            G    GVQGPPG PG PG + QP    +P +   P      V G    +    IP     
Sbjct: 814  GLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGP 873

Query: 1446 -GAPGSPG 1452
             G PGSPG
Sbjct: 874  IGPPGSPG 881



 Score =  514 bits (1324), Expect = e-145
 Identities = 309/707 (43%), Positives = 352/707 (49%), Gaps = 109/707 (15%)

Query: 810  PPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQG 869
            P  K    G  G++GE GF G  G PG PG  GP+G  G  G  G+ G PGPPGP G +G
Sbjct: 34   PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRG 93

Query: 870  LPGTAGKEGTKGDPGPP---GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPG 926
             PG  G  GT G PG P   GAPG  G  G  G  GERG PG+ G PGL+G  GP G PG
Sbjct: 94   PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPG 153

Query: 927  PAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPG 986
              G PG    +   GP G PG PGP G  G  G  G+PG  GP GP G  G  GP GLPG
Sbjct: 154  MKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPG 213

Query: 987  P--------AGPPGVAGEDGDKGEVGDPG-------------QKGTKGNKGEHGPPGPPG 1025
            P         GP G  GE G +G  G PG             QKG +G  G+ GPPGPPG
Sbjct: 214  PKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273

Query: 1026 PIGPVGQPGA-AGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET 1084
              GP G PG   G  GE G  G +G  G  G+ G  G  G PG  G  G PG  GEKG+ 
Sbjct: 274  IRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQK 333

Query: 1085 GDVGPMGPP-------------------GPPGPRGPAGPNGADGPQGPPG-----GVGNL 1120
            GD GP GPP                   G PG  G  G  G  G QGPPG     G   +
Sbjct: 334  GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM 393

Query: 1121 GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN- 1179
            GPPG  G PGE G  G +G PG+  P    G  G  GQPG PG PGP GP G   P  + 
Sbjct: 394  GPPGPPGFPGERGQKGDEGPPGISIP----GPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449

Query: 1180 ---PGPVGFPGDPGPPGEGGPRGQDGAKGDRGE-------------DGEPGQPGSPGPTG 1223
               PGP   PG PG PG+ G +G+ G KGD+G+              G+PG PG PGP G
Sbjct: 450  ICEPGP---PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPG 506

Query: 1224 ENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPV-------GPAGPAGKP 1276
              G PG  G++G AG+ G +G  G  GA G PG  G+ G+ G +       G  G  G P
Sbjct: 507  SLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSP 566

Query: 1277 GPDGLRGLPGSVGQQGRPGATGQAGPP---------GPVGPPGLPGLRGDAGAK------ 1321
            G  GL GLPG+ GQ G PG  G  G P         GP G PGLPGL G+ G        
Sbjct: 567  GAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFG 626

Query: 1322 -----GEKGHPGLIGLIGPPGEQGEKGD-------RGLPGPQGSPGQKGEMGIPGASGPI 1369
                 GEKG  G+ G  G PG  G KGD        G PG  G+PG+ G++G+PG  G  
Sbjct: 627  PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP 686

Query: 1370 GPGGPPGLPGPAGPKGAK--GATGPGGPKGEKGVQGPPGHPGPPGEV 1414
            G  G PG+PG  G  G    G  GP GPKG  G+ GPPG PG PG +
Sbjct: 687  GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRI 733



 Score =  377 bits (967), Expect = e-104
 Identities = 245/607 (40%), Positives = 281/607 (46%), Gaps = 117/607 (19%)

Query: 291  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 350
            G  G  G KGE  ++ P     GPPGP G  G  G PG++G+ G  G PG  GP G  G 
Sbjct: 887  GASGFPGTKGEMGMMGP----PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGS 942

Query: 351  PGSDGAPGPPGTSLMLPFRFGSGG--------------GDKGPVVAAQEAQAQAILQQAR 396
             G  G PGPPG   M P   GS G              G KG      +     +  Q  
Sbjct: 943  KGEPGLPGPPGP--MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQP- 999

Query: 397  LALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGA 456
              L GPPGP G  G PG  G  G PGLKG  GD+G  GP+G +G  GP G  G+ G  G 
Sbjct: 1000 -GLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGL 1058

Query: 457  DGARGMPGDPGVK--------GDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDD 508
             G +G  GDPG+         G +G  GLPG PG  G +G  G  GLPG PG  G +G  
Sbjct: 1059 PGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQP 1118

Query: 509  GEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV------RGMDGPQGPKGSLGPQGEPGPP 562
            G  G  G PG  GP+G+ GP G PG+PG PG        G  GP G KG  G  G PGP 
Sbjct: 1119 GLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPA 1178

Query: 563  GQQGTPGTQGL--PGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPG------KEGPPG 614
            GQ+G PG  G   PGP G  G  G+KG  G PG+PG PG  GP G PG       +GPPG
Sbjct: 1179 GQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPG 1238

Query: 615  TKGNQGPS--------GPQGPLGYPGPRGVKGVDG------------IRGLKGHKGEKGE 654
              G+ GP+        GPQGP G PGP G +G+ G            I+G KG+ G+ G 
Sbjct: 1239 PPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGL 1298

Query: 655  DGFPGFKGDIG---------------VKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG- 698
             G PG KGD G               +KGD G  GVPG  G  GP G  G  GP G+PG 
Sbjct: 1299 PGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGL 1358

Query: 699  -----PPGL----------------------MGEKGKLGVPGLPGYPGRQGPKGS---LG 728
                 PPGL                       G KG  G  G  G PG  GP G     G
Sbjct: 1359 IGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNG 1418

Query: 729  FPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG-------AKGTSGGD 781
             PGF GA G KG  GL G+ G RG  GP GP G +GP G  G S         + +   D
Sbjct: 1419 LPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTD 1478

Query: 782  GPHGPPG 788
             P  P G
Sbjct: 1479 APQCPQG 1485



 Score =  101 bits (251), Expect = 7e-21
 Identities = 68/169 (40%), Positives = 81/169 (47%), Gaps = 14/169 (8%)

Query: 1289 GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGP---PGEQGEKGDR 1345
            GQ     A     P       G+ G +G+ G  G +GHPGL G  GP   PG +G+KGD 
Sbjct: 21   GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80

Query: 1346 GLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPP 1405
            G+PGP G  G +G  G+PG  G       PGLPG  G  GA G  G  G  G KG +G P
Sbjct: 81   GIPGPPGPKGIRGPPGLPGFPGT------PGLPGMPGHDGAPGPQGIPGCNGTKGERGFP 134

Query: 1406 GHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTG--GAPGSPG 1452
            G PG PG    P P  +P    +   GS +M      P G  G PG PG
Sbjct: 135  GSPGFPGLQGPPGPPGIP--GMKGEPGSIIMSSLPG-PKGNPGYPGPPG 180


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score =  989 bits (2558), Expect = 0.0
 Identities = 592/1329 (44%), Positives = 673/1329 (50%), Gaps = 206/1329 (15%)

Query: 291  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 350
            GP G+ G KGEP      +++   PGP+G  G  GPPGIQG PGP G PG  GPPG  GL
Sbjct: 147  GPPGIPGMKGEPG----SIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGL 202

Query: 351  PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYT- 409
             G  G PG PG    +   F    G+KG                    L+GPPGP G   
Sbjct: 203  MGPPGPPGLPGPKGNMGLNFQGPKGEKG-----------------EQGLQGPPGPPGQIS 245

Query: 410  ---------------GRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRA 454
                           G PG  G PG PG++G  G   P G +G +G  G PGK   RG+ 
Sbjct: 246  EQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGP--PGGEKGEKGEQGEPGK---RGKP 300

Query: 455  GADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPG----PPGEDGERGDDGE 510
            G DG  G PG PG+ GD G+ G PG  GEKG +GDTG  G PG     PG     G+ G 
Sbjct: 301  GKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGN 360

Query: 511  IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGE-----------P 559
            IG  GLPGE G RG  G +GPPG+PGPPG   M GP GP G  G +G+           P
Sbjct: 361  IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM-GPPGPPGFPGERGQKGDEGPPGISIP 419

Query: 560  GPPGQQGTPGTQGLPGPQGAIGPH-------GEKGPQGKPGLPG---------------- 596
            GPPG  G PG  GLPGP G  GPH        E GP G PG PG                
Sbjct: 420  GPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGD 479

Query: 597  ---------MPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKG 647
                     + G  G PG PG  GPPG+ G  G  G +G  G  GP+G+ G+ G  G  G
Sbjct: 480  TCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPG 539

Query: 648  HKGEKGEDG----FPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLM 703
              G KGE G    FPG KGD G  G  G  G+PG  G  G +G  G  GP G+PG     
Sbjct: 540  FPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFK 599

Query: 704  GEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQR 763
            GE+G  G PGLPG PG  GP G  GF G PG  GEKG +G++G  G  G  GP G  GQ 
Sbjct: 600  GERGPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQT 658

Query: 764  GPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKG-----------PPGPPG 812
              +   GK G  G  G DG  G PG+ GLPG  G  G PG KG           PPGP G
Sbjct: 659  ITQ--PGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKG 716

Query: 813  KDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAG-----------------ETGPMGE 855
              G+PG PG  G  G  G  GPPGPPG  GP+G  G                   GP G+
Sbjct: 717  FPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGD 776

Query: 856  RGHPGPPGPPGE---QGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGG 912
            RG PGPPGPPG     GLPG  G  G  G PGP G PG  G  G++G PG  G+PG  G 
Sbjct: 777  RGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG-IGVQGPPGPPGIPGPIGQ 835

Query: 913  PGLKGNEGPSGPPGPAG-----SPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEK 967
            PGL G  G  G PGP G      PGERG+ G  G  GP G PG  G PG AG  G PG K
Sbjct: 836  PGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTK 895

Query: 968  GPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPI 1027
            G +G  G  G  GP+G+PG +G PG+ G+DG +G+ G PG  G KG+KGE G PGPPGP+
Sbjct: 896  GEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPM 955

Query: 1028 GP-----VGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNG------PPGPIGLQGLPG 1076
             P      G+ G  G  G PG  GP+G+ G  GD G  G +G      PPGP G  GLPG
Sbjct: 956  DPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPG 1015

Query: 1077 PSG---EKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG-----------GVGNLGP 1122
              G     G  G +G MG PGP G  GP GP+G  G  G PG           G+ ++G 
Sbjct: 1016 QPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGL 1075

Query: 1123 PGEKGEPGESGSPGIQGEPGVKGPRGERG---------EKGESGQPGEPGPPGPKGPTGD 1173
            PG  G  GE G PG  G PG+KG  G+ G          KG+ G PG PG PGP GP G 
Sbjct: 1076 PGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGI 1135

Query: 1174 DGPKGNPG------PVG---FPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGE 1224
             GP GNPG      PVG    PG PGPPGE G  GQDG  G  G+ GEPGQPG   P G 
Sbjct: 1136 SGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNP-GP 1194

Query: 1225 NGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAG--------PAGKP 1276
             G PG  G++G  G PG  G  G  G KG+PG  G PG  GP GP G        P G P
Sbjct: 1195 PGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNP 1254

Query: 1277 GPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPP 1336
            GP G  G PG  G +G PG  G  G  G  G PG PGL G  G KG++G PGL G  G P
Sbjct: 1255 GPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRP 1314

Query: 1337 GEQGEKGDRGLPGPQGSPGQKGEMGIPGASGP------IGPGGPPGLPGPAGPK------ 1384
            G  G KGD GLPG  G PG KG  G+PG++GP      IGP GPPGLPGP+G        
Sbjct: 1315 GLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGD 1374

Query: 1385 -GAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP 1443
             G  G  G  G KG  G QGP G PGP G    P    +P       DG+   + D  +P
Sbjct: 1375 AGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP-----GFDGAGGRKGDPGLP 1429

Query: 1444 TGGAPGSPG 1452
              G PG+ G
Sbjct: 1430 --GQPGTRG 1436



 Score =  896 bits (2316), Expect = 0.0
 Identities = 559/1273 (43%), Positives = 637/1273 (50%), Gaps = 196/1273 (15%)

Query: 291  GPRGLKGEKGEPAVLEPGMLVEGPPGP-------------------EGPAGLIGPPGIQG 331
            GP+G KGE+G          ++GPPGP                   +G  G  GPPG  G
Sbjct: 224  GPKGEKGEQG----------LQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273

Query: 332  NPGPVGDP-------GERGPPGRAGLPGSDGAPGPPGTSLM--------LPFRFGSGG-- 374
              GP G P       GE+G PG+ G PG DG  G PG   +         P R G  G  
Sbjct: 274  IRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQK 333

Query: 375  GDKGP-----VVAAQEAQAQAILQQARLAL---------RGPPGPMGYTGRPGP-----L 415
            GD GP     +V  +      I ++  + L         RG PG  G  G PGP     +
Sbjct: 334  GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM 393

Query: 416  GQPGSPGLKGESGDLGPQGP-----RGPQGLTGPPGKAGRRGRAGADGAR---------- 460
            G PG PG  GE G  G +GP      GP GL G PG  G  G  G  G            
Sbjct: 394  GPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEP 453

Query: 461  GMPGDPGVKGDRGFDGLPGLPGEKGH----------RGDTGAQGLPGPPGEDGERGDDGE 510
            G PG PG  GD+G  G  G+ G+KG            G  G  GLPG PG  G  G  G+
Sbjct: 454  GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQ 513

Query: 511  IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRG-------MDGPQGPKGSLGPQGEPGPPG 563
             G +G  G +GP+GL G  G PG PG PG +G         G +G KG LG  G PG PG
Sbjct: 514  KGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573

Query: 564  QQGTPGTQGLPGPQGAIGP------HGEKGPQGKPGLPGMPGSDGPPGHP--GKEGPPGT 615
              GTPG  GLPG  G  G        GE+GP G PGLPG+PG+ GP G P  G  GP G 
Sbjct: 574  LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGE 633

Query: 616  KGNQGPSGPQGPLGYPGPRGVKGVDGIR-GLKGHKGEKGEDGFPGFKGDIGVKGDRGEVG 674
            KG QG +G  G  G PGP+G  G    + G  G  G  G DG  G  GD G+ G  G  G
Sbjct: 634  KGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPG 693

Query: 675  VPGSRGE--------DGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQ----- 721
            +PGS+GE         GP GPKG  G  G PG PG  G  G  G PG PG+PG +     
Sbjct: 694  IPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF 753

Query: 722  ---GPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTS 778
               GP G  G PGF GA G KG RG  G  GP G  G  G  G +G  G  G+ G  G  
Sbjct: 754  ALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPP 813

Query: 779  G--GDGPHGPPGERGLPGP---QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGF---QG 830
            G  G G  GPPG  G+PGP    G +G PG KG PGPPG D +PG PG+RG  G     G
Sbjct: 814  GLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLD-VPGPPGERGSPGIPGAPG 872

Query: 831  KTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG 890
              GPPG PG+ G  GA+G  G  GE G  GPPGPPG  G+PG +G  G KGD G  G PG
Sbjct: 873  PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPG 932

Query: 891  KDGPAGLRGFPGERGLPGTAG--GPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGR 948
              GP G +G  GE GLPG  G   P L G++G  G PG  G PG  G  G  G  G PG+
Sbjct: 933  LPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQ 992

Query: 949  PGPQ------GPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGP---AGPPGVAGEDGD 999
            PG        GPPG  G  G+PG+ G IGP G  G  G +G PGP    GPPG +G  G 
Sbjct: 993  PGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQ 1052

Query: 1000 KGEVGDPGQKGTKGNKGEH--------GPPGPPGPIGPVGQPGAAGADGEPGARGPQGHF 1051
             G  G PGQKG KG+ G          GP G PG  G  G PG  G+ G+PG  G  G  
Sbjct: 1053 PGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTP 1112

Query: 1052 GAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPM------GPPGPPGPRGPAGPN 1105
            GAKG  G  GF G PGP G +G+ GP G  G  G+ GP+      G PGPPG +G  G +
Sbjct: 1113 GAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQD 1172

Query: 1106 GADGPQGPPG-----GVGNLGP---PGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESG 1157
            G  GP G  G     G GN GP   PG  G+ G+ G PGI G PG+ GP+GE G  G  G
Sbjct: 1173 GIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPG 1232

Query: 1158 QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG 1217
              G PGPPG  GP   +GPKGNPGP G PG PG PG  GP G  G  G +GE G PGQPG
Sbjct: 1233 VQGPPGPPGSPGP-ALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPG 1291

Query: 1218 SPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG 1277
             P      G PG  G +GP G  G+ GR G  G KGDPG  G PG  G  GP+       
Sbjct: 1292 LP------GLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPS------- 1338

Query: 1278 PDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLP-GLRGDAGAKGEKGHPGLIGLIGPP 1336
                 G+PGS G +G PG  G  GPPG  GP G    ++GDAG  G  G PGL GL GP 
Sbjct: 1339 -----GVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQ 1393

Query: 1337 GEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPK 1396
            G Q      GLPGP G PG  G  G+PG  G  G  G PGLPG  G +G        GP 
Sbjct: 1394 GPQ------GLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGL------DGPP 1441

Query: 1397 GEKGVQGPPGHPG 1409
            G  G+QGPPG PG
Sbjct: 1442 GPDGLQGPPGPPG 1454



 Score =  878 bits (2268), Expect = 0.0
 Identities = 545/1231 (44%), Positives = 624/1231 (50%), Gaps = 159/1231 (12%)

Query: 270  PGEEEEILESSLLPPLE-EAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPG 328
            PG   +I E     P++ E   G +GL G++G P    PG  + GPPGP  P G  G  G
Sbjct: 238  PGPPGQISEQKR--PIDVEFQKGDQGLPGDRGPPG--PPG--IRGPPGP--PGGEKGEKG 289

Query: 329  IQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--GDKGP-----VV 381
             QG PG  G PG+ G  G+ G+PG  G PG PG     P R G  G  GD GP     +V
Sbjct: 290  EQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGE----PGRDGEKGQKGDTGPPGPPGLV 345

Query: 382  AAQEAQAQAILQQARLAL---------RGPPGPMGYTGRPGP-----LGQPGSPGLKGES 427
              +      I ++  + L         RG PG  G  G PGP     +G PG PG  GE 
Sbjct: 346  IPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGER 405

Query: 428  GDLGPQGPRG-----PQGLTGPPGKAGRRGRAGADGAR----------GMPGDPGVKGDR 472
            G  G +GP G     P GL G PG  G  G  G  G            G PG PG  GD+
Sbjct: 406  GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDK 465

Query: 473  GFDGLPGLPGEKGHR----------GDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGP 522
            G  G  G+ G+KG            G  G  GLPG PG  G  G  G+ G +G  G +GP
Sbjct: 466  GLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGP 525

Query: 523  RGLLGPKGPPGIPGPPGVRG-------MDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG 575
            +GL G  G PG PG PG +G         G +G KG LG  G PG PG  GTPG  GLPG
Sbjct: 526  KGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPG 585

Query: 576  PQGAIGP------HGEKGPQGKPGLPGMPGSDGPPGHPG--KEGPPGTKGNQGPSGPQGP 627
              G  G        GE+GP G PGLPG+PG+ GP G PG    GP G KG QG +G  G 
Sbjct: 586  LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQ 645

Query: 628  LGYPGPRGVKGVDGIR-GLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDG--- 683
             G PGP+G  G    + G  G  G  G DG  G  GD G+ G  G  G+PGS+GE G   
Sbjct: 646  PGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPG 705

Query: 684  -----PEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQG--------PKGSLGFP 730
                 P GPKG  G  G PG PG  G  G  G PG PG+PG +G        P G  G P
Sbjct: 706  IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLP 765

Query: 731  GFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSG--GDGPHGPPG 788
            GF GA G KG RG  G  GP G  G  G  G +G  G  G+ G  G  G  G G  GPPG
Sbjct: 766  GFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPG 825

Query: 789  ERGLPGPQGP---NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGP---PGPPGVVG 842
              G+PGP G    +G PG KG PGPPG D +PG PG+RG  G  G  GP   PG PG+ G
Sbjct: 826  PPGIPGPIGQPGLHGIPGEKGDPGPPGLD-VPGPPGERGSPGIPGAPGPIGPPGSPGLPG 884

Query: 843  PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG 902
              GA+G  G  GE G  GPPGPPG  G+PG +G  G KGD G  G PG  GP G +G  G
Sbjct: 885  KAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKG 944

Query: 903  ERGLPGTAG--GPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQG------P 954
            E GLPG  G   P L G++G  G PG  G PG  G  G  G  G PG+PG  G      P
Sbjct: 945  EPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGP 1004

Query: 955  PGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAG---PPGVAGEDGDKGEVGDPGQKGT 1011
            PG  G  G+PG+ G IGP G  G  G +G PGP G   PPG +G  G  G  G PGQKG 
Sbjct: 1005 PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064

Query: 1012 KGNKGEH--------GPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFN 1063
            KG+ G          GP G PG  G  G PG  G+ G+PG  G  G  GAKG  G  GF 
Sbjct: 1065 KGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP 1124

Query: 1064 GPPGPIGLQGLPGPSGEKGETGDVGPMG------PPGPPGPRGPAGPNGADGPQGPPG-- 1115
            G PGP G +G+ GP G  G  G+ GP+G       PGPPG +G  G +G  GP G  G  
Sbjct: 1125 GTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEP 1184

Query: 1116 ---GVGNLGPPGE---KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKG 1169
               G GN GPPG     G+ G+ G PGI G PG+ GP+GE G  G  G  G PGPPG  G
Sbjct: 1185 GQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG 1244

Query: 1170 PTGDDGPKGNPGPVGFPGDPGPPGEGGPRG---QDGAKGDRGEDGEPGQPGSPGPTGENG 1226
            P  + GPKGNPGP G PG PG PG  GP G     G KG++G  G+PG PG PG  G+ G
Sbjct: 1245 PALE-GPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQG 1303

Query: 1227 PPGPLGK---------RGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG 1277
            PPG  G          +G  G PG  G  G KG  G PG+ G  G+ G +GP GP G PG
Sbjct: 1304 PPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPG 1363

Query: 1278 PDGLR----------GLPGSVGQQGRPGATGQAGPPGPVGPPGLP---GLRGDAGAKGEK 1324
            P G            G+PG  G +G PG  G  G PGP GPPG P   GL G  GA G K
Sbjct: 1364 PSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRK 1423

Query: 1325 GHPGLIGLIGPPGEQGEKGDRGLPGPQGSPG 1355
            G PGL G  G  G  G  G  GL GP G PG
Sbjct: 1424 GDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1454



 Score =  819 bits (2115), Expect = 0.0
 Identities = 491/1070 (45%), Positives = 556/1070 (51%), Gaps = 115/1070 (10%)

Query: 467  GVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLL 526
            G+KG++G  G PGL   +GH G  G  G  GPPG  G++GDDG      +PG  GP+G+ 
Sbjct: 42   GIKGEKGERGFPGL---EGHPGLPGFPGPEGPPGPRGQKGDDG------IPGPPGPKGIR 92

Query: 527  GPKGPPGIPGPPGVRGM------DGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAI 580
            GP G PG PG PG+ GM       GPQG  G  G +GE G PG  G PG QG PGP G  
Sbjct: 93   GPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIP 152

Query: 581  GPHGE---------KGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYP 631
            G  GE          GP+G PG PG PG  G PG  G  GP G  G  G  GP GP G P
Sbjct: 153  GMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLP 212

Query: 632  GPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIG-------VKGDRGEVGVPGSRGEDGP 684
            GP+G  G++  +G KG KGE+G  G PG  G I        V+  +G+ G+PG R   GP
Sbjct: 213  GPKGNMGLN-FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDR---GP 268

Query: 685  EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 744
             GP G  GP G PG  G  GEKG+ G PG  G PG+ G  G  G PG PG  G  G  G 
Sbjct: 269  PGPPGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326

Query: 745  SGKSGPRGERGPTGPRGQRGPRGATGKS-GAKGTSGGDGPHGPPGERGLPGPQGPNGFPG 803
             G+ G +G+ GP GP G   PR  TG + G KG  G  G  G  GERG PG QGP G PG
Sbjct: 327  DGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPG 386

Query: 804  PKGPP--GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERG---- 857
            P G    GPPG  G PG  GQ+G+ G  G    PGPPG+ G  GA G  GP G  G    
Sbjct: 387  PPGAAVMGPPGPPGFPGERGQKGDEGPPG-ISIPGPPGLDGQPGAPGLPGPPGPAGPHIP 445

Query: 858  ------HPGPPGPPGEQGLPGTAGKEGTKGDPGPPG----APGKDGPAGLRGFPGERGLP 907
                   PGPPGPPG  G  G  G++G KGD G         G  GP G  G PG  G P
Sbjct: 446  PSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPP 505

Query: 908  GTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGP----QGPPGAAGEKGV 963
            G+ G PG KG +G +G  GP G PG  GA G+ G  G  G PG      G  G  GE G 
Sbjct: 506  GSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGS 565

Query: 964  PGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPP-- 1021
            PG  G  G  G  G  G  GLPGP G PG     G++G  G+PG  G  GN G  GPP  
Sbjct: 566  PGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF 625

Query: 1022 GPPGPIGPVGQPGAAGADGEPGARGPQGHFGA-------------KGDEGTRGFNGPPGP 1068
            GPPGP+G  G  G AG  G+PG  GP+G  G               G +G  G  G PG 
Sbjct: 626  GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGL 685

Query: 1069 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1128
             G  GLPG  G KGE G  G +G PGPPGP+G  G  G  G  G PG +G  GPPG  G 
Sbjct: 686  PGQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGF 744

Query: 1129 PGESGSPGI-----QGEPGVKGPRGERGEKGESGQPGEPGPPGP------KGPTGDDGPK 1177
            PG  G PG       G PG+ G +G  G KG+ G PG PGPPG        GP GD GP 
Sbjct: 745  PGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804

Query: 1178 GNPGPVGFP--------GDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG--SPGPTGENGP 1227
            G PGP+G P        G PGPPG  GP GQ G  G  GE G+PG PG   PGP GE G 
Sbjct: 805  GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGS 864

Query: 1228 PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGS 1287
            PG  G  GP G PGS G  G  GA G PG  G  G  GP GP GP G PG  G+ GL G 
Sbjct: 865  PGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924

Query: 1288 VGQQGRPGATGQAGPPGPVGPPGLPGLRGD-----AGAKGEKGHPGLIGLIGPPGEQGEK 1342
             G QG+PG  G  G  G  G PGLPG  G       G+KGEKG PGL G+   PG  G K
Sbjct: 925  DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGI---PGVSGPK 981

Query: 1343 GDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQ 1402
            G +GLPG  G PG  G+ G+PG  GP G  G PG PG  GP G KG  G  G  G +GV+
Sbjct: 982  GYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVE 1041

Query: 1403 GPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1452
            GPPG  G PG+   P            + G +  + D  I + G PG PG
Sbjct: 1042 GPPGPSGVPGQPGSP-----------GLPGQKGDKGDPGISSIGLPGLPG 1080



 Score =  776 bits (2003), Expect = 0.0
 Identities = 459/1017 (45%), Positives = 527/1017 (51%), Gaps = 81/1017 (7%)

Query: 284  PLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 343
            P ++   G +G+KG+KG+      G  + GPPG  G  GL GPPG  G PG  G+ G+ G
Sbjct: 462  PGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAG 521

Query: 344  PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKG-----PVVAAQEAQAQAILQQARLA 398
              G  GLPG  GAPG PG        F    G+ G     P +   + +  +        
Sbjct: 522  ATGPKGLPGIPGAPGAPG--------FPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573

Query: 399  LRGPPGPMGYTGRPGPLGQPG------------SPGLKGESGDLGPQGPRGPQGLTGPPG 446
            L G PG  G  G PGP G+PG            +PGL G  G++GP GP G     GPPG
Sbjct: 574  LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG----FGPPG 629

Query: 447  KAGRRGRAGADGARGMPGDPGVKGDRGFD----GLPGLPGEKGHRGDTGAQGLPGPPGED 502
              G +G  G  G  G PG PG KGD G      G PGLPG  G  GD G  G PG PG+ 
Sbjct: 630  PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689

Query: 503  GERGDDGEIGPRG-----LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQG 557
            G  G  G  G  G     LPG  GP+G  G  GPPG PG PG  G++GP GP G  GP+G
Sbjct: 690  GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG 749

Query: 558  EPG-----PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG---PPGHPGK 609
            EPG     PPG  G PG +G  GP+G  G  G  GP G+ GL G+PG  G   P G PG 
Sbjct: 750  EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGP 809

Query: 610  EGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGED--GFPGFKGDIGVK 667
             GPPG  G  G  GP GP G PGP G  G+ GI G KG  G  G D  G PG +G  G+ 
Sbjct: 810  MGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIP 868

Query: 668  GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL 727
            G  G +G PGS G  G  G  G  G  G+ G  G  G  G LG+PG  G PG +G  G  
Sbjct: 869  GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ 928

Query: 728  GFPGFPGASGEKGARGLSGKSGPRGERGPT--GPRGQRGPRGATGKSGAKGTSGGDGPHG 785
            G PG PG +GEKG++G  G  GP G   P   G +G++G  G  G  G  G  G  G  G
Sbjct: 929  GQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPG 988

Query: 786  PPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGF------QGKTGPPGPPG 839
             PG+ GL G  G  G PGPKG PG PG+ GL G PG +G +G       QG  GPPGP G
Sbjct: 989  DPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSG 1048

Query: 840  VVGPQGAAGETGPMGERGHPGP--------PGPPGEQGLPGTAGKEGTKGDPGPPGAPGK 891
            V G  G+ G  G  G++G PG         PGP GE GLPG  G  G KG  G PG PG 
Sbjct: 1049 VPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGL 1108

Query: 892  DGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPG---R 948
             G  G +G PG  G PGT G PG KG  GP G PG  G PG  G  G  G  GPPG   +
Sbjct: 1109 PGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGK 1168

Query: 949  PGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQ 1008
            PG  G PG AG+KG PG+ G  G  G  G+ G  G  G  G PG+ G  G  G  G+PG 
Sbjct: 1169 PGQDGIPGPAGQKGEPGQPG-FGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGF 1227

Query: 1009 KGTKGNKGEHGPPGPPGPI--GPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP 1066
             G  G +G  GPPG PGP   GP G PG  G  G PG  GP+G  G  G+ G +G  G P
Sbjct: 1228 HGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNP 1287

Query: 1067 GPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEK 1126
            G  GL GLPG    KG+ G  G  G PG PG  G  G  G  G  G PG  G  G PG  
Sbjct: 1288 GQPGLPGLPGL---KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSA 1344

Query: 1127 GEPGESGSPGIQGEPGVKGPRGERGE-KGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGF 1185
            G  GE G  G  G PG+ GP G+    KG++G PG PG PG KG  G  GP+G PGP G 
Sbjct: 1345 GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGP 1404

Query: 1186 PGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGS 1242
            PGDPG  G  G  G  G KGD      PG PG PG  G +GPPGP G +GP G PG+
Sbjct: 1405 PGDPGRNGLPGFDGAGGRKGD------PGLPGQPGTRGLDGPPGPDGLQGPPGPPGT 1455



 Score =  559 bits (1440), Expect = e-159
 Identities = 357/848 (42%), Positives = 405/848 (47%), Gaps = 159/848 (18%)

Query: 757  TGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL 816
            +G +G++G RG  G  G  G  G  GP GPPG RG  G  G  G PGPKG  GPP   GL
Sbjct: 41   SGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPP---GL 97

Query: 817  PGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGK 876
            PG PG  G  G  G  G PGP G+ G  G  GE G  G  G PG  GPPG  G+PG  G+
Sbjct: 98   PGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGE 157

Query: 877  EGT---KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP---PGPAGS 930
             G+      PGP G PG  GP G++G PG  G+PG  G PG  G  GP GP   PGP G+
Sbjct: 158  PGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGN 217

Query: 931  --------PGERGAAGSGGPIGPPGR-------------------PGPQGPPGAAGEKGV 963
                     GE+G  G  GP GPPG+                   PG +GPPG  G +G 
Sbjct: 218  MGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP 277

Query: 964  P----GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHG 1019
            P    GEKG  G  G  G +G  G  G  G PG+ G  GD G  G+PG+ G KG KG+ G
Sbjct: 278  PGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTG 337

Query: 1020 PPGPPGPI-------------GPVGQPGAAGADGE---------------PGA--RGPQG 1049
            PPGPPG +             G +G PG  G  GE               PGA   GP G
Sbjct: 338  PPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG 397

Query: 1050 HFGAKGDEGTRGFNGP-----PGPIGLQGLPGPSGEKGETGDVGPMGP-------PGPPG 1097
              G  G+ G +G  GP     PGP GL G PG  G  G  G  GP  P       PGPPG
Sbjct: 398  PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG 457

Query: 1098 PRGPAGPNGADGPQGPPG----------GVGNLGPPGEKGEPGESGSPGIQGEPGVKGPR 1147
            P G  G  G  G QG  G          G G  GPPG+ G PG  G PG  G PG KG +
Sbjct: 458  PPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEK 517

Query: 1148 GERGEKGESGQPGEPGPPGP----------------KGPTGDDGPKGNPGPVGFPGDPGP 1191
            G+ G  G  G PG PG PG                  G  GD G  G+PG  G PG PG 
Sbjct: 518  GQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT 577

Query: 1192 PGEG------GPRGQDGA---KGDRGEDGEPGQPGSPGPTGEN-----GPPGPLGKRGPA 1237
            PG+       GP+G+ G    KG+RG  G PG PG PG  G       GPPGP+G++G  
Sbjct: 578  PGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQ 637

Query: 1238 GSPGSEGRQGGKGAKGDPGAI----------GAPGKTGPVGPAGPAGKPGPDGLRGLPGS 1287
            G  G+ G+ G  G KGDPG            G PG+ G VG  G  G PG  GL G+PGS
Sbjct: 638  GVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGS 697

Query: 1288 VGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRG- 1346
             G+ G PG     G PGP GP G PG+ G  GA G  G  GL G  GPPG  G KG+ G 
Sbjct: 698  KGEPGIPG----IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF 753

Query: 1347 -LPGPQGSP---------GQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPK 1396
             LPGP G P         G KG+ G PG  GP G  G  GLPGP G  G  G  GP GP 
Sbjct: 754  ALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPP 813

Query: 1397 GEK--GVQGPPGHPGPPGEVIQP----LPIQM--PKKTRRSVDGSRLMQEDEAIPTG--- 1445
            G    GVQGPPG PG PG + QP    +P +   P      V G    +    IP     
Sbjct: 814  GLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGP 873

Query: 1446 -GAPGSPG 1452
             G PGSPG
Sbjct: 874  IGPPGSPG 881



 Score =  552 bits (1423), Expect = e-157
 Identities = 341/783 (43%), Positives = 386/783 (49%), Gaps = 131/783 (16%)

Query: 291  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPG---------IQGNPGPVGDPGE 341
            G  G+ G KGEP +  PG+ + GPPGP+G  G+ GPPG         ++G PGP G PG 
Sbjct: 690  GLPGIPGSKGEPGI--PGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGP 747

Query: 342  RG--------PPGRAGLPGSDGA---------PGPPGTSLMLPFRFGSGG--GDKGPVVA 382
            +G        PPG  GLPG  GA         PGPPG     P R G  G  G KG V  
Sbjct: 748  KGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGP----PGRTGLDGLPGPKGDVGP 803

Query: 383  AQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQG-------- 434
              +           + ++GPPGP G    PGP+GQPG  G+ GE GD GP G        
Sbjct: 804  NGQPGPMGPPGLPGIGVQGPPGPPGI---PGPIGQPGLHGIPGEKGDPGPPGLDVPGPPG 860

Query: 435  ------------PRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG--------------- 467
                        P GP G  G PGKAG  G  G  G  GM G PG               
Sbjct: 861  ERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPG 920

Query: 468  VKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED-----GERGDDGEIGPRGLPGESGP 522
            +KGD G  G PGLPG  G +G  G  GLPGPPG       G +G+ GE G  G+PG SGP
Sbjct: 921  LKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGP 980

Query: 523  RGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG---PPGQQGTPGTQGLPGPQGA 579
            +G  G  G PG PG  G  G+ GP GPKG+ G  G+PG   PPG +GT G  G PGPQG 
Sbjct: 981  KGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGV 1040

Query: 580  IGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGV 639
             GP G  G  G+PG PG+PG  G  G PG     G  G  GP G  G  GYPG  G+KG 
Sbjct: 1041 EGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSI-GLPGLPGPKGEPGLPGYPGNPGIKGS 1099

Query: 640  ---DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGD 696
                G+ GL G  G KG+ G PGF G  G  G +G  G PG+ G  G  GP G  G  G 
Sbjct: 1100 VGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQ 1159

Query: 697  PGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGF-----PGFPGASGEKGARGLSG----- 746
            PGPPG   EKGK G  G+PG  G++G  G  GF     PG PG SG+KG  GL G     
Sbjct: 1160 PGPPG---EKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNP 1216

Query: 747  -KSGPRGERGPTGPRGQRGPRGATGKSGA--KGTSGGDGPHGPPGERGLPGPQGPNGFPG 803
               GP+GE G  G  G +GP G  G  G   +G  G  GP GPPG  GLPGP+GP G PG
Sbjct: 1217 GLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPG 1276

Query: 804  P---------------------KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVG 842
                                  KG  GPPG  G PG PG  G  G  G  G PG PG+ G
Sbjct: 1277 NGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKG 1336

Query: 843  PQGAAGETGPMGERGHPGPPGPPGEQG-------LPGTAGKEGTKGDPGPPGAPGKDGPA 895
            P G  G  GP GE G  GPPGPPG  G       + G AG  G  G PG  G PG  GP 
Sbjct: 1337 PSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQ 1396

Query: 896  GLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPP 955
            GL   PG  G PG  G  GL G +G  G  G  G PG+ G  G  GP GP G  GP GPP
Sbjct: 1397 GL---PGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPP 1453

Query: 956  GAA 958
            G +
Sbjct: 1454 GTS 1456



 Score =  514 bits (1324), Expect = e-145
 Identities = 309/707 (43%), Positives = 352/707 (49%), Gaps = 109/707 (15%)

Query: 810  PPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQG 869
            P  K    G  G++GE GF G  G PG PG  GP+G  G  G  G+ G PGPPGP G +G
Sbjct: 34   PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRG 93

Query: 870  LPGTAGKEGTKGDPGPP---GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPG 926
             PG  G  GT G PG P   GAPG  G  G  G  GERG PG+ G PGL+G  GP G PG
Sbjct: 94   PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPG 153

Query: 927  PAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPG 986
              G PG    +   GP G PG PGP G  G  G  G+PG  GP GP G  G  GP GLPG
Sbjct: 154  MKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPG 213

Query: 987  P--------AGPPGVAGEDGDKGEVGDPG-------------QKGTKGNKGEHGPPGPPG 1025
            P         GP G  GE G +G  G PG             QKG +G  G+ GPPGPPG
Sbjct: 214  PKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273

Query: 1026 PIGPVGQPGA-AGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET 1084
              GP G PG   G  GE G  G +G  G  G+ G  G  G PG  G  G PG  GEKG+ 
Sbjct: 274  IRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQK 333

Query: 1085 GDVGPMGPP-------------------GPPGPRGPAGPNGADGPQGPPG-----GVGNL 1120
            GD GP GPP                   G PG  G  G  G  G QGPPG     G   +
Sbjct: 334  GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM 393

Query: 1121 GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN- 1179
            GPPG  G PGE G  G +G PG+  P    G  G  GQPG PG PGP GP G   P  + 
Sbjct: 394  GPPGPPGFPGERGQKGDEGPPGISIP----GPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449

Query: 1180 ---PGPVGFPGDPGPPGEGGPRGQDGAKGDRGE-------------DGEPGQPGSPGPTG 1223
               PGP   PG PG PG+ G +G+ G KGD+G+              G+PG PG PGP G
Sbjct: 450  ICEPGP---PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPG 506

Query: 1224 ENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPV-------GPAGPAGKP 1276
              G PG  G++G AG+ G +G  G  GA G PG  G+ G+ G +       G  G  G P
Sbjct: 507  SLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSP 566

Query: 1277 GPDGLRGLPGSVGQQGRPGATGQAGPP---------GPVGPPGLPGLRGDAGAK------ 1321
            G  GL GLPG+ GQ G PG  G  G P         GP G PGLPGL G+ G        
Sbjct: 567  GAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFG 626

Query: 1322 -----GEKGHPGLIGLIGPPGEQGEKGD-------RGLPGPQGSPGQKGEMGIPGASGPI 1369
                 GEKG  G+ G  G PG  G KGD        G PG  G+PG+ G++G+PG  G  
Sbjct: 627  PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP 686

Query: 1370 GPGGPPGLPGPAGPKGAK--GATGPGGPKGEKGVQGPPGHPGPPGEV 1414
            G  G PG+PG  G  G    G  GP GPKG  G+ GPPG PG PG +
Sbjct: 687  GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRI 733



 Score =  379 bits (972), Expect = e-104
 Identities = 245/601 (40%), Positives = 277/601 (46%), Gaps = 111/601 (18%)

Query: 291  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 350
            G  G  G KGE  ++ P     GPPGP G  G  G PG++G+ G  G PG  GP G  G 
Sbjct: 887  GASGFPGTKGEMGMMGP----PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGS 942

Query: 351  PGSDGAPGPPGTSLMLPFRFGSGG--------------GDKGPVVAAQEAQAQAILQQAR 396
             G  G PGPPG   M P   GS G              G KG      +     +  Q  
Sbjct: 943  KGEPGLPGPPGP--MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQP- 999

Query: 397  LALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGA 456
              L GPPGP G  G PG  G  G PGLKG  GD+G  GP+G +G  GP G  G+ G  G 
Sbjct: 1000 -GLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGL 1058

Query: 457  DGARGMPGDPGVK--------GDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDD 508
             G +G  GDPG+         G +G  GLPG PG  G +G  G  GLPG PG  G +G  
Sbjct: 1059 PGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQP 1118

Query: 509  GEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV------RGMDGPQGPKGSLGPQGEPGPP 562
            G  G  G PG  GP+G+ GP G PG+PG PG        G  GP G KG  G  G PGP 
Sbjct: 1119 GLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPA 1178

Query: 563  GQQGTPGTQGL--PGPQGAIGPHGEKG---------------PQGKPGLPGMPGSDGPPG 605
            GQ+G PG  G   PGP G  G  G+KG               P+G+PG  G PG  GPPG
Sbjct: 1179 GQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPG 1238

Query: 606  HPGKEGPP--GTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF--- 660
             PG  GP   G KGN GP GP G  G PGP G  G+ G  G+KG KG  G+ G PG    
Sbjct: 1239 PPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1298

Query: 661  KGDIG---------------VKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG------P 699
            KGD G               +KGD G  GVPG  G  GP G  G  GP G+PG      P
Sbjct: 1299 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1358

Query: 700  PGL----------------------MGEKGKLGVPGLPGYPGRQGPKGS---LGFPGFPG 734
            PGL                       G KG  G  G  G PG  GP G     G PGF G
Sbjct: 1359 PGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDG 1418

Query: 735  ASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG-------AKGTSGGDGPHGPP 787
            A G KG  GL G+ G RG  GP GP G +GP G  G S         + +   D P  P 
Sbjct: 1419 AGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQ 1478

Query: 788  G 788
            G
Sbjct: 1479 G 1479


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score =  984 bits (2545), Expect = 0.0
 Identities = 596/1336 (44%), Positives = 675/1336 (50%), Gaps = 217/1336 (16%)

Query: 291  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 350
            GP G+ G KGEP      +++   PGP+G  G  GPPGIQG PGP G PG  GPPG  GL
Sbjct: 147  GPPGIPGMKGEPG----SIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGL 202

Query: 351  PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYT- 409
             G  G PG PG    +   F    G+KG                    L+GPPGP G   
Sbjct: 203  MGPPGPPGLPGPKGNMGLNFQGPKGEKG-----------------EQGLQGPPGPPGQIS 245

Query: 410  ---------------GRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRA 454
                           G PG  G PG PG++G  G   P G +G +G  G PGK   RG+ 
Sbjct: 246  EQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGP--PGGEKGEKGEQGEPGK---RGKP 300

Query: 455  GADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPG----PPGEDGERGDDGE 510
            G DG  G PG PG+ GD G+ G PG  GEKG +GDTG  G PG     PG     G+ G 
Sbjct: 301  GKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGN 360

Query: 511  IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGE-----------P 559
            IG  GLPGE G RG  G +GPPG+PGPPG   M GP GP G  G +G+           P
Sbjct: 361  IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM-GPPGPPGFPGERGQKGDEGPPGISIP 419

Query: 560  GPPGQQGTPGTQGLPGPQGAIGPH-------GEKGPQGKPGLPG---------------- 596
            GPPG  G PG  GLPGP G  GPH        E GP G PG PG                
Sbjct: 420  GPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGD 479

Query: 597  ---------MPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKG 647
                     + G  G PG PG  GPPG+ G  G  G +G  G  GP+G+ G+ G  G  G
Sbjct: 480  TCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPG 539

Query: 648  HKGEKGEDG----FPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLM 703
              G KGE G    FPG KGD G  G  G  G+PG  G  G +G  G  GP G+PG     
Sbjct: 540  FPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFK 599

Query: 704  GEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQR 763
            GE+G  G PGLPG PG  GP G  GF G PG  GEKG +G++G  G  G  GP G  GQ 
Sbjct: 600  GERGPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQT 658

Query: 764  GPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKG-----------PPGPPG 812
              +   GK G  G  G DG  G PG+ GLPG  G  G PG KG           PPGP G
Sbjct: 659  ITQ--PGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKG 716

Query: 813  KDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAG-----------------ETGPMGE 855
              G+PG PG  G  G  G  GPPGPPG  GP+G  G                   GP G+
Sbjct: 717  FPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGD 776

Query: 856  RGHPGPPGPPGE---QGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGG 912
            RG PGPPGPPG     GLPG  G  G  G PGP G PG  G  G++G PG  G+PG  G 
Sbjct: 777  RGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG-IGVQGPPGPPGIPGPIGQ 835

Query: 913  PGLKGNEGPSGPPGPAG-----SPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEK 967
            PGL G  G  G PGP G      PGERG+ G  G  GP G PG  G PG AG  G PG K
Sbjct: 836  PGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTK 895

Query: 968  GPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPI 1027
            G +G  G  G  GP+G+PG +G PG+ G+DG +G+ G PG  G KG+KGE G PGPPGP+
Sbjct: 896  GEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPM 955

Query: 1028 GP-----VGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNG------PPGPIGLQGLPG 1076
             P      G+ G  G  G PG  GP+G+ G  GD G  G +G      PPGP G  GLPG
Sbjct: 956  DPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPG 1015

Query: 1077 PSG---EKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG-----------GVGNLGP 1122
              G     G  G +G MG PGP G  GP GP+G  G  G PG           G+ ++G 
Sbjct: 1016 QPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGL 1075

Query: 1123 PGEKGEPGESGSPGIQGEPGVKGPRGERG---------EKGESGQPGEPGPPGPKGPTGD 1173
            PG  G  GE G PG  G PG+KG  G+ G          KG+ G PG PG PGP GP G 
Sbjct: 1076 PGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGI 1135

Query: 1174 DGPKGNPG------PVG---FPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGE 1224
             GP GNPG      PVG    PG PGPPGE G  GQDG  G  G+ GEPGQPG   P G 
Sbjct: 1136 SGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNP-GP 1194

Query: 1225 NGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGL 1284
             G PG  G++G  G PG  G  G  G KG+PG  G PG  GP    GP G PGP  L G 
Sbjct: 1195 PGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGP---PGPPGSPGP-ALEGP 1250

Query: 1285 PGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL------IGPPGE 1338
             G+ G QG PG  G  G PGP GPPGLPG  G  G KG  G PGL GL       GPPG 
Sbjct: 1251 KGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL 1310

Query: 1339 QGE---------KGDRGLPGPQGSPGQKGEMGIPGASGP------IGPGGPPGLPGPAGP 1383
            QG          KGD GLPG  G PG KG  G+PG++GP      IGP GPPGLPGP+G 
Sbjct: 1311 QGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQ 1370

Query: 1384 K-------GAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLM 1436
                    G  G  G  G KG  G QGP G PGP G    P    +P       DG+   
Sbjct: 1371 SIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP-----GFDGAGGR 1425

Query: 1437 QEDEAIPTGGAPGSPG 1452
            + D  +P  G PG+ G
Sbjct: 1426 KGDPGLP--GQPGTRG 1439



 Score =  881 bits (2276), Expect = 0.0
 Identities = 550/1260 (43%), Positives = 633/1260 (50%), Gaps = 184/1260 (14%)

Query: 291  GPRGLKGEKGEPAVLEPGMLVEGPPGP-------------------EGPAGLIGPPGIQG 331
            GP+G KGE+G          ++GPPGP                   +G  G  GPPG  G
Sbjct: 224  GPKGEKGEQG----------LQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273

Query: 332  NPGPVGDP-------GERGPPGRAGLPGSDGAPGPPGTSLM--------LPFRFGSGG-- 374
              GP G P       GE+G PG+ G PG DG  G PG   +         P R G  G  
Sbjct: 274  IRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQK 333

Query: 375  GDKGP-----VVAAQEAQAQAILQQARLAL---------RGPPGPMGYTGRPGP-----L 415
            GD GP     +V  +      I ++  + L         RG PG  G  G PGP     +
Sbjct: 334  GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM 393

Query: 416  GQPGSPGLKGESGDLGPQGP-----RGPQGLTGPPGKAGRRGRAGADGAR---------- 460
            G PG PG  GE G  G +GP      GP GL G PG  G  G  G  G            
Sbjct: 394  GPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEP 453

Query: 461  GMPGDPGVKGDRGFDGLPGLPGEKGH----------RGDTGAQGLPGPPGEDGERGDDGE 510
            G PG PG  GD+G  G  G+ G+KG            G  G  GLPG PG  G  G  G+
Sbjct: 454  GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQ 513

Query: 511  IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRG-------MDGPQGPKGSLGPQGEPGPPG 563
             G +G  G +GP+GL G  G PG PG PG +G         G +G KG LG  G PG PG
Sbjct: 514  KGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573

Query: 564  QQGTPGTQGLPGPQGAIGP------HGEKGPQGKPGLPGMPGSDGPPGHP--GKEGPPGT 615
              GTPG  GLPG  G  G        GE+GP G PGLPG+PG+ GP G P  G  GP G 
Sbjct: 574  LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGE 633

Query: 616  KGNQGPSGPQGPLGYPGPRGVKGVDGIR-GLKGHKGEKGEDGFPGFKGDIGVKGDRGEVG 674
            KG QG +G  G  G PGP+G  G    + G  G  G  G DG  G  GD G+ G  G  G
Sbjct: 634  KGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPG 693

Query: 675  VPGSRGE--------DGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQ----- 721
            +PGS+GE         GP GPKG  G  G PG PG  G  G  G PG PG+PG +     
Sbjct: 694  IPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF 753

Query: 722  ---GPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTS 778
               GP G  G PGF GA G KG RG  G  GP G  G  G  G +G  G  G+ G  G  
Sbjct: 754  ALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPP 813

Query: 779  G--GDGPHGPPGERGLPGP---QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGF---QG 830
            G  G G  GPPG  G+PGP    G +G PG KG PGPPG D +PG PG+RG  G     G
Sbjct: 814  GLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLD-VPGPPGERGSPGIPGAPG 872

Query: 831  KTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG 890
              GPPG PG+ G  GA+G  G  GE G  GPPGPPG  G+PG +G  G KGD G  G PG
Sbjct: 873  PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPG 932

Query: 891  KDGPAGLRGFPGERGLPGTAG--GPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGR 948
              GP G +G  GE GLPG  G   P L G++G  G PG  G PG  G  G  G  G PG+
Sbjct: 933  LPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQ 992

Query: 949  PGPQ------GPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGP---AGPPGVAGEDGD 999
            PG        GPPG  G  G+PG+ G IGP G  G  G +G PGP    GPPG +G  G 
Sbjct: 993  PGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQ 1052

Query: 1000 KGEVGDPGQKGTKGNKGEH--------GPPGPPGPIGPVGQPGAAGADGEPGARGPQGHF 1051
             G  G PGQKG KG+ G          GP G PG  G  G PG  G+ G+PG  G  G  
Sbjct: 1053 PGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTP 1112

Query: 1052 GAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPM------GPPGPPGPRGPAGPN 1105
            GAKG  G  GF G PGP G +G+ GP G  G  G+ GP+      G PGPPG +G  G +
Sbjct: 1113 GAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQD 1172

Query: 1106 GADGPQGPPG-----GVGNLGP---PGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESG 1157
            G  GP G  G     G GN GP   PG  G+ G+ G PGI G PG+ GP+GE G  G  G
Sbjct: 1173 GIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPG 1232

Query: 1158 QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDP---GPPGEGGPRGQDGAKGDRGEDGEPG 1214
              G PGPPG  GP   +GPKGNPGP G PG P   G PG  GP G  G  G +GE G PG
Sbjct: 1233 VQGPPGPPGSPGP-ALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPG 1291

Query: 1215 QPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAG 1274
            QPG P      G PG  G +GP G  G+ GR G  G KGDPG  G PG  G  GP+G  G
Sbjct: 1292 QPGLP------GLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPG 1345

Query: 1275 KPGPDGLRGLPGSVGQQGRPGATGQA----GPPGPVGPPGLPGLRGDAGAKGEKGHPGLI 1330
              GP+G  GL G  G  G PG +GQ+    G  GP G PG PGL+G  G +G +G P   
Sbjct: 1346 SAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLP--- 1402

Query: 1331 GLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGAT 1390
               GP G  G+ G  GLPG  G+ G+KG+ G+PG  G  G  GPPG  G  GP G  G +
Sbjct: 1403 ---GPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTS 1459



 Score =  875 bits (2260), Expect = 0.0
 Identities = 543/1233 (44%), Positives = 624/1233 (50%), Gaps = 160/1233 (12%)

Query: 270  PGEEEEILESSLLPPLE-EAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPG 328
            PG   +I E     P++ E   G +GL G++G P    PG  + GPPGP  P G  G  G
Sbjct: 238  PGPPGQISEQKR--PIDVEFQKGDQGLPGDRGPPG--PPG--IRGPPGP--PGGEKGEKG 289

Query: 329  IQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--GDKGP-----VV 381
             QG PG  G PG+ G  G+ G+PG  G PG PG     P R G  G  GD GP     +V
Sbjct: 290  EQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGE----PGRDGEKGQKGDTGPPGPPGLV 345

Query: 382  AAQEAQAQAILQQARLAL---------RGPPGPMGYTGRPGP-----LGQPGSPGLKGES 427
              +      I ++  + L         RG PG  G  G PGP     +G PG PG  GE 
Sbjct: 346  IPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGER 405

Query: 428  GDLGPQGPRG-----PQGLTGPPGKAGRRGRAGADGAR----------GMPGDPGVKGDR 472
            G  G +GP G     P GL G PG  G  G  G  G            G PG PG  GD+
Sbjct: 406  GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDK 465

Query: 473  GFDGLPGLPGEKGHR----------GDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGP 522
            G  G  G+ G+KG            G  G  GLPG PG  G  G  G+ G +G  G +GP
Sbjct: 466  GLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGP 525

Query: 523  RGLLGPKGPPGIPGPPGVRG-------MDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG 575
            +GL G  G PG PG PG +G         G +G KG LG  G PG PG  GTPG  GLPG
Sbjct: 526  KGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPG 585

Query: 576  PQGAIGP------HGEKGPQGKPGLPGMPGSDGPPGHPG--KEGPPGTKGNQGPSGPQGP 627
              G  G        GE+GP G PGLPG+PG+ GP G PG    GP G KG QG +G  G 
Sbjct: 586  LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQ 645

Query: 628  LGYPGPRGVKGVDGIR-GLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDG--- 683
             G PGP+G  G    + G  G  G  G DG  G  GD G+ G  G  G+PGS+GE G   
Sbjct: 646  PGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPG 705

Query: 684  -----PEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQG--------PKGSLGFP 730
                 P GPKG  G  G PG PG  G  G  G PG PG+PG +G        P G  G P
Sbjct: 706  IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLP 765

Query: 731  GFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSG--GDGPHGPPG 788
            GF GA G KG RG  G  GP G  G  G  G +G  G  G+ G  G  G  G G  GPPG
Sbjct: 766  GFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPG 825

Query: 789  ERGLPGPQGP---NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGP---PGPPGVVG 842
              G+PGP G    +G PG KG PGPPG D +PG PG+RG  G  G  GP   PG PG+ G
Sbjct: 826  PPGIPGPIGQPGLHGIPGEKGDPGPPGLD-VPGPPGERGSPGIPGAPGPIGPPGSPGLPG 884

Query: 843  PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG 902
              GA+G  G  GE G  GPPGPPG  G+PG +G  G KGD G  G PG  GP G +G  G
Sbjct: 885  KAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKG 944

Query: 903  ERGLPGTAG--GPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQG------P 954
            E GLPG  G   P L G++G  G PG  G PG  G  G  G  G PG+PG  G      P
Sbjct: 945  EPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGP 1004

Query: 955  PGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAG---PPGVAGEDGDKGEVGDPGQKGT 1011
            PG  G  G+PG+ G IGP G  G  G +G PGP G   PPG +G  G  G  G PGQKG 
Sbjct: 1005 PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064

Query: 1012 KGNKGEH--------GPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFN 1063
            KG+ G          GP G PG  G  G PG  G+ G+PG  G  G  GAKG  G  GF 
Sbjct: 1065 KGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP 1124

Query: 1064 GPPGPIGLQGLPGPSGEKGETGDVGPMG------PPGPPGPRGPAGPNGADGPQGPPG-- 1115
            G PGP G +G+ GP G  G  G+ GP+G       PGPPG +G  G +G  GP G  G  
Sbjct: 1125 GTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEP 1184

Query: 1116 ---GVGNLGPPGE---KGEPGESGSPGIQGEPGVKGPRGE---RGEKGESGQPGEPGPPG 1166
               G GN GPPG     G+ G+ G PGI G PG+ GP+GE    G  G  G PG PG PG
Sbjct: 1185 GQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG 1244

Query: 1167 P--KGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGE 1224
            P  +GP G+ GP+G PG  GF G PGP G  G  G  G KG++G  G+PG PG PG  G+
Sbjct: 1245 PALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGD 1304

Query: 1225 NGPPGPLGK---------RGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1275
             GPPG  G          +G  G PG  G  G KG  G PG+ G  G+ G +GP GP G 
Sbjct: 1305 QGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGL 1364

Query: 1276 PGPDGLR----------GLPGSVGQQGRPGATGQAGPPGPVGPPGLP---GLRGDAGAKG 1322
            PGP G            G+PG  G +G PG  G  G PGP GPPG P   GL G  GA G
Sbjct: 1365 PGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGG 1424

Query: 1323 EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPG 1355
             KG PGL G  G  G  G  G  GL GP G PG
Sbjct: 1425 RKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1457



 Score =  819 bits (2115), Expect = 0.0
 Identities = 491/1070 (45%), Positives = 556/1070 (51%), Gaps = 115/1070 (10%)

Query: 467  GVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLL 526
            G+KG++G  G PGL   +GH G  G  G  GPPG  G++GDDG      +PG  GP+G+ 
Sbjct: 42   GIKGEKGERGFPGL---EGHPGLPGFPGPEGPPGPRGQKGDDG------IPGPPGPKGIR 92

Query: 527  GPKGPPGIPGPPGVRGM------DGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAI 580
            GP G PG PG PG+ GM       GPQG  G  G +GE G PG  G PG QG PGP G  
Sbjct: 93   GPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIP 152

Query: 581  GPHGE---------KGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYP 631
            G  GE          GP+G PG PG PG  G PG  G  GP G  G  G  GP GP G P
Sbjct: 153  GMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLP 212

Query: 632  GPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIG-------VKGDRGEVGVPGSRGEDGP 684
            GP+G  G++  +G KG KGE+G  G PG  G I        V+  +G+ G+PG R   GP
Sbjct: 213  GPKGNMGLN-FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDR---GP 268

Query: 685  EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 744
             GP G  GP G PG  G  GEKG+ G PG  G PG+ G  G  G PG PG  G  G  G 
Sbjct: 269  PGPPGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326

Query: 745  SGKSGPRGERGPTGPRGQRGPRGATGKS-GAKGTSGGDGPHGPPGERGLPGPQGPNGFPG 803
             G+ G +G+ GP GP G   PR  TG + G KG  G  G  G  GERG PG QGP G PG
Sbjct: 327  DGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPG 386

Query: 804  PKGPP--GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERG---- 857
            P G    GPPG  G PG  GQ+G+ G  G    PGPPG+ G  GA G  GP G  G    
Sbjct: 387  PPGAAVMGPPGPPGFPGERGQKGDEGPPG-ISIPGPPGLDGQPGAPGLPGPPGPAGPHIP 445

Query: 858  ------HPGPPGPPGEQGLPGTAGKEGTKGDPGPPG----APGKDGPAGLRGFPGERGLP 907
                   PGPPGPPG  G  G  G++G KGD G         G  GP G  G PG  G P
Sbjct: 446  PSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPP 505

Query: 908  GTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGP----QGPPGAAGEKGV 963
            G+ G PG KG +G +G  GP G PG  GA G+ G  G  G PG      G  G  GE G 
Sbjct: 506  GSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGS 565

Query: 964  PGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPP-- 1021
            PG  G  G  G  G  G  GLPGP G PG     G++G  G+PG  G  GN G  GPP  
Sbjct: 566  PGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF 625

Query: 1022 GPPGPIGPVGQPGAAGADGEPGARGPQGHFGA-------------KGDEGTRGFNGPPGP 1068
            GPPGP+G  G  G AG  G+PG  GP+G  G               G +G  G  G PG 
Sbjct: 626  GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGL 685

Query: 1069 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1128
             G  GLPG  G KGE G  G +G PGPPGP+G  G  G  G  G PG +G  GPPG  G 
Sbjct: 686  PGQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGF 744

Query: 1129 PGESGSPGI-----QGEPGVKGPRGERGEKGESGQPGEPGPPGP------KGPTGDDGPK 1177
            PG  G PG       G PG+ G +G  G KG+ G PG PGPPG        GP GD GP 
Sbjct: 745  PGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804

Query: 1178 GNPGPVGFP--------GDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG--SPGPTGENGP 1227
            G PGP+G P        G PGPPG  GP GQ G  G  GE G+PG PG   PGP GE G 
Sbjct: 805  GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGS 864

Query: 1228 PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGS 1287
            PG  G  GP G PGS G  G  GA G PG  G  G  GP GP GP G PG  G+ GL G 
Sbjct: 865  PGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924

Query: 1288 VGQQGRPGATGQAGPPGPVGPPGLPGLRGD-----AGAKGEKGHPGLIGLIGPPGEQGEK 1342
             G QG+PG  G  G  G  G PGLPG  G       G+KGEKG PGL G+   PG  G K
Sbjct: 925  DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGI---PGVSGPK 981

Query: 1343 GDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQ 1402
            G +GLPG  G PG  G+ G+PG  GP G  G PG PG  GP G KG  G  G  G +GV+
Sbjct: 982  GYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVE 1041

Query: 1403 GPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1452
            GPPG  G PG+   P            + G +  + D  I + G PG PG
Sbjct: 1042 GPPGPSGVPGQPGSP-----------GLPGQKGDKGDPGISSIGLPGLPG 1080



 Score =  779 bits (2011), Expect = 0.0
 Identities = 462/1033 (44%), Positives = 534/1033 (51%), Gaps = 110/1033 (10%)

Query: 284  PLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 343
            P ++   G +G+KG+KG+      G  + GPPG  G  GL GPPG  G PG  G+ G+ G
Sbjct: 462  PGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAG 521

Query: 344  PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKG-----PVVAAQEAQAQAILQQARLA 398
              G  GLPG  GAPG PG        F    G+ G     P +   + +  +        
Sbjct: 522  ATGPKGLPGIPGAPGAPG--------FPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573

Query: 399  LRGPPGPMGYTGRPGPLGQPG------------SPGLKGESGDLGPQGPRGPQGLTGPPG 446
            L G PG  G  G PGP G+PG            +PGL G  G++GP GP G     GPPG
Sbjct: 574  LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG----FGPPG 629

Query: 447  KAGRRGRAGADGARGMPGDPGVKGDRGFD----GLPGLPGEKGHRGDTGAQGLPGPPGED 502
              G +G  G  G  G PG PG KGD G      G PGLPG  G  GD G  G PG PG+ 
Sbjct: 630  PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689

Query: 503  GERGDDGEIGPRG-----LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQG 557
            G  G  G  G  G     LPG  GP+G  G  GPPG PG PG  G++GP GP G  GP+G
Sbjct: 690  GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG 749

Query: 558  EPG-----PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG---PPGHPGK 609
            EPG     PPG  G PG +G  GP+G  G  G  GP G+ GL G+PG  G   P G PG 
Sbjct: 750  EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGP 809

Query: 610  EGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGED--GFPGFKGDIGVK 667
             GPPG  G  G  GP GP G PGP G  G+ GI G KG  G  G D  G PG +G  G+ 
Sbjct: 810  MGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIP 868

Query: 668  GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL 727
            G  G +G PGS G  G  G  G  G  G+ G  G  G  G LG+PG  G PG +G  G  
Sbjct: 869  GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ 928

Query: 728  GFPGFPGASGEKGARGLSGKSGPRGERGPT--GPRGQRGPRGATGKSGAKGTSGGDGPHG 785
            G PG PG +GEKG++G  G  GP G   P   G +G++G  G  G  G  G  G  G  G
Sbjct: 929  GQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPG 988

Query: 786  PPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGF------QGKTGPPGPPG 839
             PG+ GL G  G  G PGPKG PG PG+ GL G PG +G +G       QG  GPPGP G
Sbjct: 989  DPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSG 1048

Query: 840  VVGPQGAAGETGPMGERGHPGP--------PGPPGEQGLPGTAGKEGTKGDPGPPGAPGK 891
            V G  G+ G  G  G++G PG         PGP GE GLPG  G  G KG  G PG PG 
Sbjct: 1049 VPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGL 1108

Query: 892  DGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGP 951
             G  G +G PG  G PGT G PG KG    SGPPG  G PGE G  G GG    PG+PGP
Sbjct: 1109 PGTPGAKGQPGLPGFPGTPGPPGPKGI---SGPPGNPGLPGEPGPVGGGGH---PGQPGP 1162

Query: 952  QGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGT 1011
             G  G  G+ G+PG  G  G  G+ G     G PGP G PG++G+ GD G  G PG  G 
Sbjct: 1163 PGEKGKPGQDGIPGPAGQKGEPGQPGF----GNPGPPGLPGLSGQKGDGGLPGIPGNPGL 1218

Query: 1012 KGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGL 1071
             G KGE G  G PG  GP G PG+ G    P   GP+G+ G +G  G  GF G PGP G 
Sbjct: 1219 PGPKGEPGFHGFPGVQGPPGPPGSPG----PALEGPKGNPGPQGPPGRPGFQGLPGPEGP 1274

Query: 1072 QGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGE 1131
             GLPG  G KGE G+ G  G PG PG +G          QGPPG  GN G PG  G  G+
Sbjct: 1275 PGLPGNGGIKGEKGNPGQPGLPGLPGLKGD---------QGPPGLQGNPGRPGLNGMKGD 1325

Query: 1132 SGSPGIQGEPGVKGPRGERGEKGESGQPG---EPGPPGPKGPTG-------DDGPKGNPG 1181
             G PG+ G PG+KGP G  G  G  G+PG    PGPPG  GP+G       D GP G PG
Sbjct: 1326 PGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPG 1385

Query: 1182 ------------PVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPG 1229
                        P G PG  GPPG+ G  G  G  G  G  G+PG PG PG  G +GPPG
Sbjct: 1386 QPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPG 1445

Query: 1230 PLGKRGPAGSPGS 1242
            P G +GP G PG+
Sbjct: 1446 PDGLQGPPGPPGT 1458



 Score =  559 bits (1441), Expect = e-159
 Identities = 350/801 (43%), Positives = 403/801 (50%), Gaps = 125/801 (15%)

Query: 291  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPG---------IQGNPGPVGDPGE 341
            G  G+ G KGEP +  PG+ + GPPGP+G  G+ GPPG         ++G PGP G PG 
Sbjct: 690  GLPGIPGSKGEPGI--PGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGP 747

Query: 342  RG--------PPGRAGLPGSDGA---------PGPPGTSLMLPFRFGSGG--GDKGPVVA 382
            +G        PPG  GLPG  GA         PGPPG     P R G  G  G KG V  
Sbjct: 748  KGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGP----PGRTGLDGLPGPKGDVGP 803

Query: 383  AQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQG-------- 434
              +           + ++GPPGP G    PGP+GQPG  G+ GE GD GP G        
Sbjct: 804  NGQPGPMGPPGLPGIGVQGPPGPPGI---PGPIGQPGLHGIPGEKGDPGPPGLDVPGPPG 860

Query: 435  ------------PRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG--------------- 467
                        P GP G  G PGKAG  G  G  G  GM G PG               
Sbjct: 861  ERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPG 920

Query: 468  VKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED-----GERGDDGEIGPRGLPGESGP 522
            +KGD G  G PGLPG  G +G  G  GLPGPPG       G +G+ GE G  G+PG SGP
Sbjct: 921  LKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGP 980

Query: 523  RGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG---PPGQQGTPGTQGLPGPQGA 579
            +G  G  G PG PG  G  G+ GP GPKG+ G  G+PG   PPG +GT G  G PGPQG 
Sbjct: 981  KGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGV 1040

Query: 580  IGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGV 639
             GP G  G  G+PG PG+PG  G  G PG     G  G  GP G  G  GYPG  G+KG 
Sbjct: 1041 EGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSI-GLPGLPGPKGEPGLPGYPGNPGIKGS 1099

Query: 640  ---DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGD 696
                G+ GL G  G KG+ G PGF G  G  G +G  G PG+ G  G  GP G  G  G 
Sbjct: 1100 VGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQ 1159

Query: 697  PGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGF-----PGFPGASGEKGARGLSGKSGPR 751
            PGPPG   EKGK G  G+PG  G++G  G  GF     PG PG SG+KG  GL G  G  
Sbjct: 1160 PGPPG---EKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNP 1216

Query: 752  GERGPTGPRGQRGPRGATGKSGAKGTSGG--DGPHGPPGERGLPGPQGPNGFPGPKGPPG 809
            G  GP G  G  G  G  G  G  G+ G   +GP G PG +G PG  G  G PGP+GPPG
Sbjct: 1217 GLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPG 1276

Query: 810  PPGKDGLPG---HPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPG 866
             PG  G+ G   +PGQ G  G  G  G  GPPG+ G  G  G  G  G+ G PG PG PG
Sbjct: 1277 LPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPG 1336

Query: 867  EQG---LPGTAGKEGTKGDPGPPGAPGKDGP----------AGLRGFPGERGLPGTAGGP 913
             +G   +PG+AG EG  G  GPPG PG  GP          AG  G PG+ GL G  G  
Sbjct: 1337 MKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQ 1396

Query: 914  GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPT 973
            G +G  GP+GPPG  G  G  G  G+GG  G PG PG             PG +G  GP 
Sbjct: 1397 GPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQ------------PGTRGLDGPP 1444

Query: 974  GRDGVQGPVGLPGPAGPPGVA 994
            G DG+QGP   PGP G   VA
Sbjct: 1445 GPDGLQGP---PGPPGTSSVA 1462



 Score =  559 bits (1440), Expect = e-159
 Identities = 357/848 (42%), Positives = 405/848 (47%), Gaps = 159/848 (18%)

Query: 757  TGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL 816
            +G +G++G RG  G  G  G  G  GP GPPG RG  G  G  G PGPKG  GPP   GL
Sbjct: 41   SGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPP---GL 97

Query: 817  PGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGK 876
            PG PG  G  G  G  G PGP G+ G  G  GE G  G  G PG  GPPG  G+PG  G+
Sbjct: 98   PGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGE 157

Query: 877  EGT---KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP---PGPAGS 930
             G+      PGP G PG  GP G++G PG  G+PG  G PG  G  GP GP   PGP G+
Sbjct: 158  PGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGN 217

Query: 931  --------PGERGAAGSGGPIGPPGR-------------------PGPQGPPGAAGEKGV 963
                     GE+G  G  GP GPPG+                   PG +GPPG  G +G 
Sbjct: 218  MGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP 277

Query: 964  P----GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHG 1019
            P    GEKG  G  G  G +G  G  G  G PG+ G  GD G  G+PG+ G KG KG+ G
Sbjct: 278  PGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTG 337

Query: 1020 PPGPPGPI-------------GPVGQPGAAGADGE---------------PGA--RGPQG 1049
            PPGPPG +             G +G PG  G  GE               PGA   GP G
Sbjct: 338  PPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG 397

Query: 1050 HFGAKGDEGTRGFNGP-----PGPIGLQGLPGPSGEKGETGDVGPMGP-------PGPPG 1097
              G  G+ G +G  GP     PGP GL G PG  G  G  G  GP  P       PGPPG
Sbjct: 398  PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG 457

Query: 1098 PRGPAGPNGADGPQGPPG----------GVGNLGPPGEKGEPGESGSPGIQGEPGVKGPR 1147
            P G  G  G  G QG  G          G G  GPPG+ G PG  G PG  G PG KG +
Sbjct: 458  PPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEK 517

Query: 1148 GERGEKGESGQPGEPGPPGP----------------KGPTGDDGPKGNPGPVGFPGDPGP 1191
            G+ G  G  G PG PG PG                  G  GD G  G+PG  G PG PG 
Sbjct: 518  GQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT 577

Query: 1192 PGEG------GPRGQDGA---KGDRGEDGEPGQPGSPGPTGEN-----GPPGPLGKRGPA 1237
            PG+       GP+G+ G    KG+RG  G PG PG PG  G       GPPGP+G++G  
Sbjct: 578  PGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQ 637

Query: 1238 GSPGSEGRQGGKGAKGDPGAI----------GAPGKTGPVGPAGPAGKPGPDGLRGLPGS 1287
            G  G+ G+ G  G KGDPG            G PG+ G VG  G  G PG  GL G+PGS
Sbjct: 638  GVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGS 697

Query: 1288 VGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRG- 1346
             G+ G PG     G PGP GP G PG+ G  GA G  G  GL G  GPPG  G KG+ G 
Sbjct: 698  KGEPGIPG----IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF 753

Query: 1347 -LPGPQGSP---------GQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPK 1396
             LPGP G P         G KG+ G PG  GP G  G  GLPGP G  G  G  GP GP 
Sbjct: 754  ALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPP 813

Query: 1397 GEK--GVQGPPGHPGPPGEVIQP----LPIQM--PKKTRRSVDGSRLMQEDEAIPTG--- 1445
            G    GVQGPPG PG PG + QP    +P +   P      V G    +    IP     
Sbjct: 814  GLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGP 873

Query: 1446 -GAPGSPG 1452
             G PGSPG
Sbjct: 874  IGPPGSPG 881



 Score =  514 bits (1324), Expect = e-145
 Identities = 309/707 (43%), Positives = 352/707 (49%), Gaps = 109/707 (15%)

Query: 810  PPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQG 869
            P  K    G  G++GE GF G  G PG PG  GP+G  G  G  G+ G PGPPGP G +G
Sbjct: 34   PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRG 93

Query: 870  LPGTAGKEGTKGDPGPP---GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPG 926
             PG  G  GT G PG P   GAPG  G  G  G  GERG PG+ G PGL+G  GP G PG
Sbjct: 94   PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPG 153

Query: 927  PAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPG 986
              G PG    +   GP G PG PGP G  G  G  G+PG  GP GP G  G  GP GLPG
Sbjct: 154  MKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPG 213

Query: 987  P--------AGPPGVAGEDGDKGEVGDPG-------------QKGTKGNKGEHGPPGPPG 1025
            P         GP G  GE G +G  G PG             QKG +G  G+ GPPGPPG
Sbjct: 214  PKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273

Query: 1026 PIGPVGQPGA-AGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET 1084
              GP G PG   G  GE G  G +G  G  G+ G  G  G PG  G  G PG  GEKG+ 
Sbjct: 274  IRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQK 333

Query: 1085 GDVGPMGPP-------------------GPPGPRGPAGPNGADGPQGPPG-----GVGNL 1120
            GD GP GPP                   G PG  G  G  G  G QGPPG     G   +
Sbjct: 334  GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM 393

Query: 1121 GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN- 1179
            GPPG  G PGE G  G +G PG+  P    G  G  GQPG PG PGP GP G   P  + 
Sbjct: 394  GPPGPPGFPGERGQKGDEGPPGISIP----GPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449

Query: 1180 ---PGPVGFPGDPGPPGEGGPRGQDGAKGDRGE-------------DGEPGQPGSPGPTG 1223
               PGP   PG PG PG+ G +G+ G KGD+G+              G+PG PG PGP G
Sbjct: 450  ICEPGP---PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPG 506

Query: 1224 ENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPV-------GPAGPAGKP 1276
              G PG  G++G AG+ G +G  G  GA G PG  G+ G+ G +       G  G  G P
Sbjct: 507  SLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSP 566

Query: 1277 GPDGLRGLPGSVGQQGRPGATGQAGPP---------GPVGPPGLPGLRGDAGAK------ 1321
            G  GL GLPG+ GQ G PG  G  G P         GP G PGLPGL G+ G        
Sbjct: 567  GAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFG 626

Query: 1322 -----GEKGHPGLIGLIGPPGEQGEKGD-------RGLPGPQGSPGQKGEMGIPGASGPI 1369
                 GEKG  G+ G  G PG  G KGD        G PG  G+PG+ G++G+PG  G  
Sbjct: 627  PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP 686

Query: 1370 GPGGPPGLPGPAGPKGAK--GATGPGGPKGEKGVQGPPGHPGPPGEV 1414
            G  G PG+PG  G  G    G  GP GPKG  G+ GPPG PG PG +
Sbjct: 687  GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRI 733



 Score =  377 bits (968), Expect = e-104
 Identities = 244/604 (40%), Positives = 279/604 (46%), Gaps = 114/604 (18%)

Query: 291  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 350
            G  G  G KGE  ++ P     GPPGP G  G  G PG++G+ G  G PG  GP G  G 
Sbjct: 887  GASGFPGTKGEMGMMGP----PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGS 942

Query: 351  PGSDGAPGPPGTSLMLPFRFGSGG--------------GDKGPVVAAQEAQAQAILQQAR 396
             G  G PGPPG   M P   GS G              G KG      +     +  Q  
Sbjct: 943  KGEPGLPGPPGP--MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQP- 999

Query: 397  LALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGA 456
              L GPPGP G  G PG  G  G PGLKG  GD+G  GP+G +G  GP G  G+ G  G 
Sbjct: 1000 -GLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGL 1058

Query: 457  DGARGMPGDPGVK--------GDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDD 508
             G +G  GDPG+         G +G  GLPG PG  G +G  G  GLPG PG  G +G  
Sbjct: 1059 PGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQP 1118

Query: 509  GEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV------RGMDGPQGPKGSLGPQGEPGPP 562
            G  G  G PG  GP+G+ GP G PG+PG PG        G  GP G KG  G  G PGP 
Sbjct: 1119 GLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPA 1178

Query: 563  GQQGTPG-----------------------------TQGLPGPQGAIGPHGEKGPQGKPG 593
            GQ+G PG                               GLPGP+G  G HG  G QG PG
Sbjct: 1179 GQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPG 1238

Query: 594  LPGMPGS--DGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKG---------VDGI 642
             PG PG   +GP G+PG +GPPG  G QG  GP+GP G PG  G+KG         + G+
Sbjct: 1239 PPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGL 1298

Query: 643  RGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG---- 698
             GLKG +G  G  G PG  G  G+KGD G  GVPG  G  GP G  G  GP G+PG    
Sbjct: 1299 PGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGP 1358

Query: 699  --PPGL----------------------MGEKGKLGVPGLPGYPGRQGPKGS---LGFPG 731
              PPGL                       G KG  G  G  G PG  GP G     G PG
Sbjct: 1359 PGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPG 1418

Query: 732  FPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG-------AKGTSGGDGPH 784
            F GA G KG  GL G+ G RG  GP GP G +GP G  G S         + +   D P 
Sbjct: 1419 FDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQ 1478

Query: 785  GPPG 788
             P G
Sbjct: 1479 CPQG 1482



 Score =  101 bits (251), Expect = 7e-21
 Identities = 68/169 (40%), Positives = 81/169 (47%), Gaps = 14/169 (8%)

Query: 1289 GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGP---PGEQGEKGDR 1345
            GQ     A     P       G+ G +G+ G  G +GHPGL G  GP   PG +G+KGD 
Sbjct: 21   GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80

Query: 1346 GLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPP 1405
            G+PGP G  G +G  G+PG  G       PGLPG  G  GA G  G  G  G KG +G P
Sbjct: 81   GIPGPPGPKGIRGPPGLPGFPGT------PGLPGMPGHDGAPGPQGIPGCNGTKGERGFP 134

Query: 1406 GHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTG--GAPGSPG 1452
            G PG PG    P P  +P    +   GS +M      P G  G PG PG
Sbjct: 135  GSPGFPGLQGPPGPPGIP--GMKGEPGSIIMSSLPG-PKGNPGYPGPPG 180


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score =  943 bits (2438), Expect = 0.0
 Identities = 663/1875 (35%), Positives = 844/1875 (45%), Gaps = 308/1875 (16%)

Query: 28   GAPP-VDVLRALRFPSLPDGVRRAKGICPADVAYRVARPAQLSAPTRQLFPGGFPKDFSL 86
            GAP  VD+L+ L       G     G+ P    +   + A+L APT  + P     + +L
Sbjct: 41   GAPEDVDILQRLGLSWTKAGSPAPPGVIPFQSGFIFTQRARLQAPTGTVIPAALGTELAL 100

Query: 87   LTVVRTRPGLQAPLLTLYSAQGVRQLGLEL--GRPVRFLYEDQTGRPQPPSQPVFRGLSL 144
            +  + +     A L  + S +   QLGL+   G+ V  L   ++         V   L +
Sbjct: 101  VLSLCSHRVNHAFLFAVRSQKRKLQLGLQFLPGKTVVHLGSRRS---------VAFDLDM 151

Query: 145  ADGKWHRVAVAVKGQSVTLIVDC-KKRVTRPLPRSARPVLDTHGVIIFGARILDEEVFEG 203
             DG+WH +A+ ++G++VTL+  C ++RV   LP    P LD  G  +FG        FEG
Sbjct: 152  HDGRWHHLALELRGRTVTLVTACGQRRVPVLLPFHRDPALDPGGSFLFGKMNPHAVQFEG 211

Query: 204  DVQELAIVPGVQAAYESCEQKELECEGGQRERPQ-------NQQPHR------------- 243
             + + +I P  Q A+  C     +C  GQ +  Q       +Q   R             
Sbjct: 212  ALCQFSIYPVTQVAHNYCTHLRKQC--GQADTYQSPLGPLFSQDSGRPFTFQSDLALLGL 269

Query: 244  --------------AQRSPQ--QQPSRLHRPQNQEPQSQD---------PTPGEEEEILE 278
                          A R P+    P+   +PQ   P +            TP    ++  
Sbjct: 270  ENLTTATPALGSLPAGRGPRGTVAPATPTKPQRTSPTNPHQHMAVGGPAQTPLLPAKLSA 329

Query: 279  SSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEG-------PPGPEGPAGLIGP----- 326
            S+ L P+  A+ G          PA  +P   +         P  P  P+  I P     
Sbjct: 330  SNALDPMLPASVGG---STRTPRPAAAQPSQKITATKIPKSLPTKPSAPSTSIVPIKSPH 386

Query: 327  ----------------------PGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSL 364
                                  P  +  P  V  P E+      G+P     P PP T  
Sbjct: 387  PTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPAEKPIQRNPGMP----RPPPPSTRP 442

Query: 365  MLPFRFGSGGGDKGPVVAAQEAQAQAILQQ---ARLALRGPPGPMGYTGRPGPLGQPGSP 421
            + P    S      P +A  EA+  +   +   AR +   PP     +  P P   PGS 
Sbjct: 443  LPPTT--SSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSPAP--TPGST 498

Query: 422  GLKGESGDLGPQGPRGPQGLTGP----PGKAGRRGRAGADGARGMPGDPGVKGDRGFDGL 477
                    + P         T P    PG A    +            P     +     
Sbjct: 499  RSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEASKKAGPKSSPRKPVPLR 558

Query: 478  PGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGL------PGESG---------- 521
            PG         D   +  P  P    +      + P         P  SG          
Sbjct: 559  PGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAGST 618

Query: 522  PRGLL-GPKGP---------PGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP--------- 562
            P  LL GP GP         PG+PG PG+ G  GP+GP G  G  G PGPP         
Sbjct: 619  PFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDP 678

Query: 563  ------------GQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPP---GHP 607
                        G  G PG  G PGP G  G  G  GP G PG  G PG +G P   G+P
Sbjct: 679  GLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYP 738

Query: 608  GKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF------K 661
            G++G PG  G+ GP G +G +G PG  G+ G DG RGL G  G++G+ G PGF      +
Sbjct: 739  GRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGER 798

Query: 662  GDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP------------PGLMGEKGKL 709
            G  G+ G+ GE+G+PG  G  G  G  G  GP G PGP            PGL G+KG+ 
Sbjct: 799  GPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQ 858

Query: 710  GVPGLPGYPGRQGPKGSLGFPGFPGAS---------GEKGARGLSGKSGPRGERGPTGPR 760
            GVPG+ G PG QG KGS G PGFPGA          G+KG+ G  G  GP G  G  GP 
Sbjct: 859  GVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPP 918

Query: 761  GQRGPRGATGKSGAK---------GTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPP 811
            G  GP G  GK GA+         G  G +GP GPPG  GL G  G  GFPG  G  G  
Sbjct: 919  GDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVK 978

Query: 812  GKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLP 871
            G+ G PG PG  GE GF G  G  G PG+VG +G  G  GP      PG PGP G  G P
Sbjct: 979  GEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGP------PGVPGPKGSMGHP 1032

Query: 872  GTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGP---A 928
            G  G  GT G+PGP G PG  GP G+RG  G RG  G  G  G +G+ G  GPPGP    
Sbjct: 1033 GMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRP 1092

Query: 929  GSPGERGAAGSGGPIGP---PGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLP 985
            G PG++G AG  G +G    PG PGP GPPG  G  G PG +GP GP G  G  GP G P
Sbjct: 1093 GRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPP 1152

Query: 986  GPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGAR 1045
            G  G PG+ GE G KG++G  G  G +G  G+ G PG  G  GP+G  G  G  G+P   
Sbjct: 1153 GAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDP--- 1209

Query: 1046 GPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGP------SGEKGET---------GDVGPM 1090
            GP G  G KG EG  G +GPPGP G+ G+ GP       GEKG T         G +G M
Sbjct: 1210 GPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEM 1269

Query: 1091 GPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGER 1150
            G PG PGP G  GP G+ G  GP G  G +G  GE G  G  G  GI G  G  GP+GE+
Sbjct: 1270 GVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEK 1329

Query: 1151 GEKGESGQ-PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGE 1209
            GE+GE G+  G PGPPG +GP GD G +G       PGDPG PG+ G +G  G  G +G+
Sbjct: 1330 GEQGEDGKAEGPPGPPGDRGPVGDRGDRGE------PGDPGYPGQEGVQGLRGKPGQQGQ 1383

Query: 1210 DGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGP 1269
             G PG  G PGP G  G  GP GK+G AG+P   GR+G +G +G PG  G  G+ G  G 
Sbjct: 1384 PGHPGPRGWPGPKGSKGAEGPKGKQGKAGAP---GRRGVQGLQGLPGPRGVVGRQGLEGI 1440

Query: 1270 AGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGL 1329
            AGP G PG DG  G  G  G  G PG  G AG  G  G  GLPG +G  G KGE G P  
Sbjct: 1441 AGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLP-- 1498

Query: 1330 IGLIGPPGEQGEKGDRGLPGPQGSPGQK------GEMGIPGASGPIGPGGPP-------- 1375
             G +GPPG++G +G  GLPG QG PG K      GEMG PG +G  GP GPP        
Sbjct: 1499 -GQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGI 1557

Query: 1376 -------------------------GLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGP 1410
                                     GLPGP G KG++G  G  GP+G  G +G PG PGP
Sbjct: 1558 QGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGP 1617

Query: 1411 PGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQ 1470
            PG  IQ     +    +  +D S  ++ +            GG  EIF +L  L   I+ 
Sbjct: 1618 PGGPIQLQQDDLGAAFQTWMDTSGALRPESYSYPDRLVLDQGG--EIFKTLHYLSNLIQS 1675

Query: 1471 MRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGETCVTP- 1529
            ++ P GT+++PAR C+DL  C  ++ DG YWVDPN GC+ D   V CNFT GG+TC+ P 
Sbjct: 1676 IKTPLGTKENPARVCRDLMDCEQKMVDGTYWVDPNLGCSSDTIEVSCNFTHGGQTCLKPI 1735

Query: 1530 RDDVTQFSYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPCSGAA--RDG--------PLR 1579
                 +F+        +  VQ+ FL LLS    Q ++  C      ++G         +R
Sbjct: 1736 TASKVEFA--------ISRVQMNFLHLLSSEVTQHITIHCLNMTVWQEGTGQTPAKQAVR 1787

Query: 1580 LRGANED--ELSPETSPYVKEFRDGCQTQQGR---TVLEVRTPVLEQLPVLDASFSDLGA 1634
             R  N    E   +  P V    DGC+ Q GR   T+   RT   +QLP++        +
Sbjct: 1788 FRAWNGQIFEAGGQFRPEVS--MDGCKVQDGRWHQTLFTFRTQDPQQLPIISVDNLPPAS 1845

Query: 1635 PPRRGGVLLGPVCFM 1649
              ++  + +GP CF+
Sbjct: 1846 SGKQYRLEVGPACFL 1860


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  929 bits (2402), Expect = 0.0
 Identities = 586/1359 (43%), Positives = 676/1359 (49%), Gaps = 234/1359 (17%)

Query: 291  GPRGLKGEKGEPAVLEPGMLVE----GPPGPEGPAGLIGPPGIQGNPGPVGDPGE----- 341
            GP G KGEKG+     PG+  +    G  GP GP G IGP G +G PGP+G+ GE     
Sbjct: 1439 GPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERG 1498

Query: 342  -------RGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG-----GDK---GPVVAAQEA 386
                   RG PG AG PG+ G  GPPG +     R G  G     GD    GP VA  + 
Sbjct: 1499 PPGPAGSRGLPGVAGRPGAKGPEGPPGPT----GRQGEKGEPGRPGDPAVVGPAVAGPKG 1554

Query: 387  QAQAILQQARLALRGPPGPMGYTGRPGPLGQPG-----SPGLKGESGDLGP---QGPRGP 438
            +   +         GP GP G TG  G  G PG      PG KG+ GD GP    G  GP
Sbjct: 1555 EKGDV---------GPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGP 1605

Query: 439  QGLTGPPGKAGRRGRAGADGA---RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGL 495
             G +GPPG+ G  GR G  G    RG  G+ G KGD G  G PGLPG+ G RG  GA G+
Sbjct: 1606 PGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGV 1665

Query: 496  PGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPG-------------PPGVRG 542
             GP GE G++GD GE G  G PG SGP+G  G  GPPG PG              PG RG
Sbjct: 1666 RGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRG 1725

Query: 543  MDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQG---AIGPHGEKGPQGKPGLPGMPG 599
             +GP+GPKG     G PG PG++G  G +G PGPQG     GP GEKG +G PGL G  G
Sbjct: 1726 QEGPRGPKGD---PGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSG 1782

Query: 600  SDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPG 659
             DG PG  G  GP G  G  G  G  G    PG RG +G+ G  G  G  G+ GEDG PG
Sbjct: 1783 LDGKPGAAGPSGPNGAAGKAGDPGRDG---LPGLRGEQGLPGPSGPPGLPGKPGEDGKPG 1839

Query: 660  FKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG------ 713
              G  G  GD GE G  G +G+ G  G +GR GP G+ G PG++G +G  G+PG      
Sbjct: 1840 LNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPG 1899

Query: 714  --LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSG------------------------- 746
               PG PG  GPKG  G  G  G  G  G RGL G                         
Sbjct: 1900 QGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREI 1959

Query: 747  -----------------KSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPG- 788
                             + GP+G+ G  GP G+ GP G  G+ G KG  G  GP GPPG 
Sbjct: 1960 VETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGL 2019

Query: 789  ---ERGLPGPQGPNGFPGPKGPPGPPGKDG------LPGHPGQRGEVGF---QGKTGPPG 836
               ERG PGP G  G PG  G PG PG+ G       PG  G+RGE G    QG+ GPPG
Sbjct: 2020 ALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPG 2079

Query: 837  PPGVVGPQGAAG------ETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG 890
             PG  GP G  G      E GP G  G  GPPG  G +G PG+ G +G KGD G PG  G
Sbjct: 2080 LPGTPGPPGPPGPKVSVDEPGP-GLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKG 2138

Query: 891  KDGPAGLRG------FPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIG 944
              G  G RG       PGERG+ G  G PGL+G  GP GP G  G PG  GA G  GP G
Sbjct: 2139 DRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAG 2198

Query: 945  PPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVG 1004
            P G  G +G PG  G  G  G  GP G  G  G  GP GL GP G PG+ G+ G+ G+ G
Sbjct: 2199 PQGPSGLKGEPGETGPPG-RGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPG 2257

Query: 1005 DPGQKGTKGNKGEHGPPGPPG------PIGPVGQPGAAGADGEPGARGPQGHFGAKGDEG 1058
             PG+ G  G  G+ G PG PG      P+GP G+PG  GA G+     P    GAKG++G
Sbjct: 2258 APGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLP----GAKGEKG 2313

Query: 1059 TRG-----FNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGP 1113
              G       G PG  G +GLPGP GEKGE G  G  G PG  G +G  GP G  G  G 
Sbjct: 2314 APGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGV 2373

Query: 1114 --PGGVGNLGPPGEKGE---PGESGSPGIQGEPGVKGPRGERGEKGESGQ------PGEP 1162
              PG  G  GPPG KG+   PG  G+PG+ G PG  GPRGE G+ G SG+      PG  
Sbjct: 2374 GVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGRE 2433

Query: 1163 GPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEG--GPRGQDGAKGDRGEDGEPGQPGSPG 1220
            G PGP GP G  G  G PG  G  GD G PG G  GPRG+ G  G RGEDG PGQ G   
Sbjct: 2434 GIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEG--- 2490

Query: 1221 PTGENGPPGPLGKRGPAGSPGSEGRQGGKG-------------AKGDPGAIGAPGKTGPV 1267
            P G  GPPG  G+RG  G  GS G +G KG             AKGD G  G  G  G  
Sbjct: 2491 PRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDK 2550

Query: 1268 GPAGPAGKPGPDGLRGLPGS------------VGQQGRPGATGQAGPPGPVGPPGLPGLR 1315
            GP G  G PG  G +G PG             +G QG+PGA G  G PG  G  G+PG+R
Sbjct: 2551 GPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIR 2610

Query: 1316 GDAG------AKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPI 1369
            G+ G       +G KG  G+ G  G  GE+G+KG+ G PG  G  G KGEMG PG  G  
Sbjct: 2611 GEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQS 2670

Query: 1370 GPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPG---------------HPGPPGEV 1414
            G  G  GL GP G +G  G  GP G +GEKG +G PG                PGPPG V
Sbjct: 2671 GAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSV 2730

Query: 1415 IQPLPIQMP-KKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1452
                P  +  +K  R   G R++         GAPG PG
Sbjct: 2731 GPRGPEGLQGQKGERGPPGERVV---------GAPGVPG 2760



 Score =  925 bits (2390), Expect = 0.0
 Identities = 580/1416 (40%), Positives = 674/1416 (47%), Gaps = 258/1416 (18%)

Query: 228  CEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEE 287
            C  GQ+  P  +   R Q  P   P    R     PQ                  PP   
Sbjct: 1251 CPKGQKGEP-GEMGLRGQVGPPGDPGLPGRTGAPGPQG-----------------PPGSA 1292

Query: 288  AAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGR 347
             A G RG  G  G P    PG    G PG  G  GL G PG+   PGP GDPGERGP G 
Sbjct: 1293 TAKGERGFPGADGRPG--SPGR--AGNPGTPGAPGLKGSPGL---PGPRGDPGERGPRGP 1345

Query: 348  AGLPGSDG------APGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRG 401
             G PG+ G       PG PG             GD GP                     G
Sbjct: 1346 KGEPGAPGQVIGGEGPGLPGRK-----------GDPGP--------------------SG 1374

Query: 402  PPGPMGYTGRPGPLGQPGSPG--LKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 459
            PPGP G  G PGP G PG PG  +KG+ GD G +GP GP      PG+ G  G  G+ G 
Sbjct: 1375 PPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGP 1434

Query: 460  RGMPGDPGVKGDRG--FDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLP 517
            +G  G PG KG++G   DG PGLPG+ G  G+ G +G PG  G  G+RG  G +G  G  
Sbjct: 1435 QGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEK 1494

Query: 518  GESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQ-----------QG 566
            GE GP G  G +G PG+ G PG +G +GP GP G  G +GEPG PG            +G
Sbjct: 1495 GERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKG 1554

Query: 567  TPGTQGLPGPQGAIGPHGEKGP-----QGKPGLPGMPGSDGP------PGHPGKEGPPGT 615
              G  G  GP+GA G  GE+GP      G PG  G PG  GP       G PG  GPPG 
Sbjct: 1555 EKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGE 1614

Query: 616  KGNQGPSGPQGPL------GYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGD 669
            KG+ G  GP GP+      G  G +G +G  G  GL G  GE+G  G PG +G +G KGD
Sbjct: 1615 KGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGD 1674

Query: 670  RGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK-LGVPGLPGYPGRQGPKGSLG 728
            +G+ G  G  G  G  GPKG  G  G PGPPG + + G      G PG  G++GP+G  G
Sbjct: 1675 QGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKG 1734

Query: 729  FPGFPGASGEKGARGLSGKSGPRGE---RGPTGPRGQRGPRGATGKSGAKGTSGGDGPHG 785
             PG PGA GE+G  G  G  GP+G+   RGP G +G RGP G  G+SG  G  G  GP G
Sbjct: 1735 DPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSG 1794

Query: 786  P---------PGERGLPGPQGPNGFPGPKGPPGPPGK---DGLPGHPGQRGEVGFQGKTG 833
            P         PG  GLPG +G  G PGP GPPG PGK   DG PG  G+ GE G  G+ G
Sbjct: 1795 PNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDG 1854

Query: 834  PPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGK-----EGTKGDPGPPGA 888
              G  G  G  G  G  GP GERG PG  GP G  GLPG  G       G  G  GP G 
Sbjct: 1855 RKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGD 1914

Query: 889  PGKDGPAGLRGFPGERGLPGTAG------------------------------------- 911
             G+ G  G +G PGERGL G  G                                     
Sbjct: 1915 RGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVP 1974

Query: 912  ----GP-GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP-------GPQGPPGAAG 959
                GP G  G +GP G  GP G PGERG  G  G  GP G P       GP GP G AG
Sbjct: 1975 ERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAG 2034

Query: 960  EKGVP------------------------GEKGPIGPTGRDGVQGPVGLPGPAGPPG--V 993
            E G P                        GEKG  G  GRDG  G  G PGP GPPG  V
Sbjct: 2035 EPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKV 2094

Query: 994  AGED---GDKGEVGDPGQKGTKGNKGEHGPPGP------PGPIGPVGQPGAAGADGEPGA 1044
            + ++   G  GE G PG KG KG  G +G  GP      PG  G  G+PG  G DG PG 
Sbjct: 2095 SVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGL 2154

Query: 1045 RGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGP------PGPPGP 1098
             G +G  G +G  G +G  GPPGP+G  G PGP G  G  G  GP GP      PG  GP
Sbjct: 2155 PGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGP 2214

Query: 1099 --RGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGES 1156
              RG  GP GA G  GPPG  G +GP G  G PG+ G  G  G PG  G  G+ G++G  
Sbjct: 2215 PGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSP 2274

Query: 1157 GQPGEPGPPGPKGPTGDDGPKGNPG---------------PVGFPGD-PGPPGEGGPRGQ 1200
            G PG PG PGP GP G+ GP G PG               P G  GD  G PG  G RG 
Sbjct: 2275 GVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGL 2334

Query: 1201 DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGP--AGSPGSEGRQGGKGAKGD---- 1254
             G +G++GE G  G+PG PG  G+ G PGP G +G    G PGS G  G  G KGD    
Sbjct: 2335 PGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLP 2394

Query: 1255 --PGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLP 1312
              PGA G  G  G  GP G  G+PGP G RGL G  G++G PG  G  GPPG VGPPG  
Sbjct: 2395 GLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGAS 2454

Query: 1313 GLRGD--------AGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPG 1364
            GL+GD         G +GE+G PG+ G  G PG++G +G  G PG +G  G+KG++G  G
Sbjct: 2455 GLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAG 2514

Query: 1365 ASGP-------IGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQP 1417
              G        +GP GP G  G  G +G +G  G  GP+G+ G  G  G  G PG+    
Sbjct: 2515 LKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGD---- 2570

Query: 1418 LPIQMPKKTRRSVDGSRLMQEDEAIP-TGGAPGSPG 1452
                   K    + G R +   +  P   G PG PG
Sbjct: 2571 -------KGSAGLPGLRGLLGPQGQPGAAGIPGDPG 2599



 Score =  808 bits (2087), Expect = 0.0
 Identities = 521/1297 (40%), Positives = 614/1297 (47%), Gaps = 237/1297 (18%)

Query: 241  PHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEAAH----GPRGLK 296
            P  A R   + P     P  ++ +  +P    +  ++  ++  P  E       GPRG  
Sbjct: 1509 PGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGAT 1568

Query: 297  GEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGD---PGERGPPGRAGLPG- 352
            G +GE     PG+++ G PGP+G  G  GP G+ G  GP GD   PGE+G PGR G PG 
Sbjct: 1569 GVQGERG--PPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGP 1626

Query: 353  --------------SDGAPGPPGTSLMLPFRFGSGG-----GDKGPVVAAQEAQAQAILQ 393
                           +G PG PG    LP + G  G     G +GPV   ++       +
Sbjct: 1627 VGPRGRDGEVGEKGDEGPPGDPG----LPGKAGERGLRGAPGVRGPV--GEKGDQGDPGE 1680

Query: 394  QARLALRGPPGPMGYTGRPGPLGQPG-----SPGL--KGESGDLGPQGPRGPQGLTGPPG 446
              R    G  GP G  G PGP G PG      PG   KGE GD G +GPRGP+G  G PG
Sbjct: 1681 DGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPG 1740

Query: 447  KAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERG 506
              G RG  G  G  G  GDPGV+G  G  G  G PG  G  G  G  G  GP G +G  G
Sbjct: 1741 APGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAG 1800

Query: 507  DDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV-------------------------- 540
              G+ G  GLPG  G +GL GP GPPG+PG PG                           
Sbjct: 1801 KAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKG 1860

Query: 541  -------RGMDGPQGPKGS---LGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQG 590
                    G DGP+G +G+   LGPQG PG PG  G PG QG PG  G  GP G++G  G
Sbjct: 1861 DSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPG-QGFPGVPGGTGPKGDRGETG 1919

Query: 591  KPGLPGMPGSDGPPGHPG---------------------------------------KEG 611
              G  G+PG  G  G PG                                       + G
Sbjct: 1920 SKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRG 1979

Query: 612  PPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKG-EKGEDGFPGFKGDIGVKGDR 670
            P G  G QGP G +GP+G+PG RG+KG  G  G +G  G   GE G PG     G+ G+ 
Sbjct: 1980 PKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPG---PSGLAGEP 2036

Query: 671  GEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKG---SL 727
            G+ G+PG  G  G  G  GR G  G+ G  G  GE+G+ G PGLPG PG  GP G   S+
Sbjct: 2037 GKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSV 2096

Query: 728  GFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPP 787
              PG PG SGE+G  GL G  G  G  G  GP+G RG  G  G  G  G  G DG  G P
Sbjct: 2097 DEPG-PGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLP 2155

Query: 788  GERGLPGPQGPNGFPGPKGPPGPPG---KDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ 844
            GERG+ GP+G  G  GP+GPPGP G     G PG PG  G  G QG +G  G PG  GP 
Sbjct: 2156 GERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPP 2215

Query: 845  GAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGER 904
            G  G TGP G  G PGPPGP G  G  G+ G  G  G+ G PGAPG+DG +G     G+R
Sbjct: 2216 GR-GLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGK---DGDR 2271

Query: 905  GLPGTAGGPGLKGNEGPSGPPGPAGSPGE------------------------------- 933
            G PG  G PGL G  GP G PGP G+PG+                               
Sbjct: 2272 GSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGD 2331

Query: 934  RGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKG-----------PIGPTGRDGVQGPV 982
            RG  G  G  G  GR G  G PG  G+KG PG KG             GP G  GV+G +
Sbjct: 2332 RGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDL 2391

Query: 983  GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPG---------PPGPIGPVGQP 1033
            GLPG  G PGV G  G  G  G+ GQ G  G +G  GPPG         PPGP G VG P
Sbjct: 2392 GLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPP 2451

Query: 1034 GAAGADGEPG-----ARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVG 1088
            GA+G  G+ G       GP+G  G  G  G  G  G  GP GL G PG  GE+GE GDVG
Sbjct: 2452 GASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVG 2511

Query: 1089 P-------------MGPPGPPGPRGPAG---PNGADGPQGPPGGVGNLGPPGEKGEPGES 1132
                          +GPPGP G +G  G   P G DG +GP G  G+ G  G KGEPG+ 
Sbjct: 2512 SAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDK 2571

Query: 1133 GSPGIQGEPGVKGPRGERGEKGESGQPGEPGP---PGPKGPTGD---------DGPKGNP 1180
            GS G+ G  G+ GP+G+ G  G  G PG PG    PG +G  GD          G +G  
Sbjct: 2572 GSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVK 2631

Query: 1181 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1240
            G  G  G+ G  GE GP G+ G  G +GE GEPG PG  G  G+ G  GP G RG  G P
Sbjct: 2632 GACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQP 2691

Query: 1241 GSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG------PDGLRGLPGS------- 1287
            G +G QG KG +G PG  G PG +G  G AGP G PG      P+GL+G  G        
Sbjct: 2692 GPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGER 2751

Query: 1288 -VGQQGRPGATGQA------GPPGPVGPPGLPGLRGD 1317
             VG  G PGA G+       GP GP G  G   L  D
Sbjct: 2752 VVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTED 2788



 Score =  507 bits (1306), Expect = e-143
 Identities = 317/738 (42%), Positives = 368/738 (49%), Gaps = 107/738 (14%)

Query: 835  PGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGP 894
            P P  V  P+G  GE G MG RG  GPPG PG   LPG  G  G +G PG   A G+ G 
Sbjct: 1244 PEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPG---LPGRTGAPGPQGPPGSATAKGERGF 1300

Query: 895  AGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP 954
             G  G PG  G  G  G PG  G +G  G PGP G PGERG      P GP G PG  G 
Sbjct: 1301 PGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERG------PRGPKGEPGAPGQ 1354

Query: 955  PGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE--DGDKGEVGDPGQKG-- 1010
                   G+PG KG  GP+G  G +GP+G PGP GPPG+ G    GDKG+ G+ G  G  
Sbjct: 1355 VIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPG 1414

Query: 1011 ----TKGNKGEHGPPGPPGPIGPVGQPGAAG--ADGEPGARGPQGHFGAKGDEGTRGFNG 1064
                  G  G  G PG PGP GPVG PG  G   D E GA G  G  G+ G++G RG  G
Sbjct: 1415 EGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPG 1474

Query: 1065 PPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPG 1124
              GP G +G PGP GE GE G+ GP GP G  G  G AG  GA GP+GPPG  G  G  G
Sbjct: 1475 AIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKG 1534

Query: 1125 EKGEPGE--------SGSPGIQGEPGVKGPRGERGEKGESGQPG--EPGPPGPKGPTGDD 1174
            E G PG+        +G  G +G+ G  GPRG  G +GE G PG   PG PGPKG  GD 
Sbjct: 1535 EPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDR 1594

Query: 1175 GP------------KGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPT 1222
            GP             G PG  G PG PGPPG  GPRG+DG  G++G++G PG PG PG  
Sbjct: 1595 GPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKA 1654

Query: 1223 GENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK------- 1275
            GE G  G  G RGP G  G +G  G  G  G PG+ G  G  G  GP GP G+       
Sbjct: 1655 GERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPG 1714

Query: 1276 ------PGPDGLRGLPGSVGQQGRPGATGQAGPP---GPVGPPGLPGLRGDAGAKGEKGH 1326
                  PG  G  G  G  G  G PGA G+ G     GP GP G PG+RG AG KG++G 
Sbjct: 1715 AREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGP 1774

Query: 1327 PGL---------IGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIG-PG---- 1372
            PGL          G  GP G  G  G  G PG  G PG +GE G+PG SGP G PG    
Sbjct: 1775 PGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGE 1834

Query: 1373 ----------GPPGLPGPAGPKGAKGATGPG------GPKGEKGV------QGPPGHP-- 1408
                      G PG PG  G KG KG +G        GPKGE+G       QGPPG P  
Sbjct: 1835 DGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGP 1894

Query: 1409 -GPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP-TGGAPGSPGGLEEIFGSLD---- 1462
             GPPG+    +P     K  R   GS+    ++ +P   G  G PG +  +   L+    
Sbjct: 1895 VGPPGQGFPGVPGGTGPKGDRGETGSK---GEQGLPGERGLRGEPGSVPNVDRLLETAGI 1951

Query: 1463 ---SLREEIEQMRRPTGT 1477
               +LRE +E     +G+
Sbjct: 1952 KASALREIVETWDESSGS 1969



 Score =  219 bits (559), Expect = 1e-56
 Identities = 138/346 (39%), Positives = 166/346 (47%), Gaps = 27/346 (7%)

Query: 283  PPLEEAAHGPRGLKGEKGEPAVLEPGMLVE----------GPPGPEGPAGLIGPPGIQGN 332
            PP      G  GLKG+KG+P V  PG   E          G PG EGP GL GPPG +G 
Sbjct: 2444 PPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGE 2503

Query: 333  PGPVGDPGERG-------------PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG-GDKG 378
             G  GD G  G             PPG  G  G  G  GP G       R  +G  GDKG
Sbjct: 2504 RGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKG 2563

Query: 379  PV-VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRG 437
                   +  A     +  L  +G PG  G  G PG  G+ G PG++GE GD+G  GPRG
Sbjct: 2564 SKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRG 2623

Query: 438  PQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPG 497
             +G  G  G  G  G  G  G  G PG PG+ G +G  G PG+PG+ G  G  G  G  G
Sbjct: 2624 LKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKG 2683

Query: 498  PPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQG 557
              G DG+ G  G+ G +G  G  G  G  GP G  G  GPPG  G  GP+GP+G  G +G
Sbjct: 2684 DRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKG 2743

Query: 558  EPGPPGQQ--GTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSD 601
            E GPPG++  G PG  G PG +G  G  G  GP+G+ G   +   D
Sbjct: 2744 ERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDD 2789



 Score =  111 bits (278), Expect = 5e-24
 Identities = 85/242 (35%), Positives = 103/242 (42%), Gaps = 38/242 (15%)

Query: 243  RAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEP 302
            R    PQ QP     P +     +D  PG   E  +   +        GPRGLKGE+G  
Sbjct: 2580 RGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFM--------GPRGLKGERGVK 2631

Query: 303  AVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGT 362
                      G  G +G  G  GPPG  G  G  G+ GE G PG++G PG +G  GP G 
Sbjct: 2632 GAC-------GLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGD 2684

Query: 363  SLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGS-- 420
                   F    G KG      E     I         G PGP G  G  GP G PGS  
Sbjct: 2685 R-----GFDGQPGPKGDQGEKGERGTPGI--------GGFPGPSGNDGSAGPPGPPGSVG 2731

Query: 421  ----PGLKGESGDLGPQGPR--GPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGD--R 472
                 GL+G+ G+ GP G R  G  G+ G PG+ G +GR G  G RG  G+  +  D  R
Sbjct: 2732 PRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIR 2791

Query: 473  GF 474
            GF
Sbjct: 2792 GF 2793


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score =  912 bits (2356), Expect = 0.0
 Identities = 583/1436 (40%), Positives = 702/1436 (48%), Gaps = 206/1436 (14%)

Query: 72   TRQLFPGGFPKDFSLLTVVRTRPGLQAP---LLTLYSAQGVRQLGLELGRPVRFLYEDQT 128
            T  +FP G P +++ +T  R R   +     +  +     + Q+ + L    + +  +  
Sbjct: 281  TEDVFPQGLPDEYAFVTTFRFRKTSRKEDWYIWQVIDQYSIPQVSIRLDGENKAVEYNAV 340

Query: 129  GRPQPPSQPVFRGL---SLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSARPVLDT 185
            G  +   + VFRG     L D  WH++A++++ Q+V+L +DC   + + LP   R  +D 
Sbjct: 341  GAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNVSLHIDCA--LVQTLPIEERENIDI 398

Query: 186  HGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQPHRAQ 245
             G  + G R+ D    + D+Q + I          C+ +  E E    + P         
Sbjct: 399  QGKTVIGKRLYDSVPIDFDLQRIVIY---------CDSRHAELETCC-DIP--------- 439

Query: 246  RSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVL 305
             S   Q + +  P    P  + PTPG E+       L  +  +   P G KGE G     
Sbjct: 440  -SGPCQVTVVTEPPPPPPPQRPPTPGSEQ----IGFLKTINCSC--PAGEKGEMGVA--- 489

Query: 306  EPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLM 365
                         GP GL GP G  G  GPVG PG +G  G  G+               
Sbjct: 490  -------------GPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIG-------------- 522

Query: 366  LPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKG 425
             PF    G G+KG              ++  L L GPPG  G  G  G  G+ G PGL G
Sbjct: 523  -PF----GQGEKG--------------EKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPG 563

Query: 426  ESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKG 485
            E   +G +GP+GP GL GPPG+ G     G  G RG  G  G KG+RG DG PG PG   
Sbjct: 564  E---VGMRGPQGPPGLPGPPGRVGA---PGLQGERGEKGTRGEKGERGLDGFPGKPG--- 614

Query: 486  HRGDTGAQGLPGPPGEDGERGDDGEIGPRGLP----------------GESGPRGLLGPK 529
               DTG QG PGP G  G +G+ G++GP G P                G  GPRG  G  
Sbjct: 615  ---DTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAP 671

Query: 530  GPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQ 589
            GPPG  GP G  G DGP G +G  G +G+ GPPG  G  G QG PGP G  GP    GP 
Sbjct: 672  GPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGP---PGPG 728

Query: 590  GKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHK 649
            G PGLPG  G  G PG PG  GPPG  G  GP GP G  G PG RG  G+ G  GL+G  
Sbjct: 729  GSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEI 788

Query: 650  GEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKL 709
            GE+G  G PG KG+ G+    G  G PG RGE G +G KG  G  G  G  G  GE G  
Sbjct: 789  GEQGLAGRPGEKGEAGLP---GAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPA 845

Query: 710  GVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGAT 769
            G PGLPG      P   +  PG  G  GEKG  GL G+ G +G  G  GP+G  GP GA 
Sbjct: 846  GPPGLPGTTSLFTPHPRM--PGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAK 903

Query: 770  GKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQ 829
            G+ GA G  G  G  G PG  G PGP GP G  G  G  G PGKDG  G  G  GE G  
Sbjct: 904  GQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSP 963

Query: 830  GKTGP---PGPPGVVGPQGAAGETGPMGERGHPGPPGP---------------------- 864
            G  GP   PG PG+ GP G  G+ G  G RG PG PGP                      
Sbjct: 964  GPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQC 1022

Query: 865  -PGEQGLPGTAGKEGTKGDP--GPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGP 921
              G++G PG  G  G++GDP  G  G PG  GP G +G PG RGLPG  G  G  G +G 
Sbjct: 1023 VKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGA 1082

Query: 922  SGPPGPAGSPGERGAAG--SGGPIG----------PPGRPGPQGPPGAAGEKGVPGEKGP 969
             G PG  G PG+ G +   S G I           PPG PG  G PG  G+KGVPG+ G 
Sbjct: 1083 PGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGR 1142

Query: 970  IGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGP 1029
             G  G+ G  GP GLP   GPPG+AG  G +GE G  G+ G KG++G    PG PG +GP
Sbjct: 1143 EGTEGKKGEAGPPGLP---GPPGIAGPQGSQGERGADGEVGQKGDQGH---PGVPGFMGP 1196

Query: 1030 VGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGP 1089
             G PG  GADG  GA GP G  G+ G EG     GP GP GL G+PG  G++G  G  GP
Sbjct: 1197 PGNPGPPGADGIAGAAGPPGIQGSPGKEGP---PGPQGPSGLPGIPGEEGKEGRDGKPGP 1253

Query: 1090 MGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE------PGESGSPGIQGEPGV 1143
             G PG  G  G  GP GA GP G  G  G+ G PG +GE      PG+ G PG  G+ G 
Sbjct: 1254 PGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGP 1313

Query: 1144 KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGA 1203
             GP+G +G +G  G+ G PG PG  GP+G  G KG+ G  G PG PG  G  GP G+ G 
Sbjct: 1314 TGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGE 1373

Query: 1204 KGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGP---AGSPGSEGRQGGKGAKGDPGAIGA 1260
            KG  G++G PG+PG PG  GE G PG  G +GP    G PG  G  G KG  G  G  G 
Sbjct: 1374 KGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGL 1433

Query: 1261 PGKTGPVGPAGPAGKPGPDGLRG-----------LPGSVGQQ----------GRPGA--T 1297
            PG+ GPVGP GP G+PG  GLRG           +   +G+Q            P A   
Sbjct: 1434 PGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMK 1493

Query: 1298 GQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQK 1357
               G PGP GPPG  GL G AG  GE G PG  GL GP G  G KG+RG  G  G+PG  
Sbjct: 1494 SSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG-- 1551

Query: 1358 GEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGE 1413
              +G+ G  GP G  G PG PG A   G  G  GP G  G  G  G PG PGPPG+
Sbjct: 1552 --VGLRGEMGPPGIPGQPGEPGYA-KDGLPGIPGPQGETGPAGHPGLPGPPGPPGQ 1604



 Score =  865 bits (2235), Expect = 0.0
 Identities = 521/1172 (44%), Positives = 586/1172 (50%), Gaps = 178/1172 (15%)

Query: 412  PGPLGQPGSPGLKGESGDLG------PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGD 465
            P P  +P +PG + + G L       P G +G  G+ GP G  G +G  GA G  G PG 
Sbjct: 454  PPPPQRPPTPGSE-QIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGP 512

Query: 466  PGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGE---RGDDGEIGPRGLPGESGP 522
             G KGD G       P  +G +G+ G+ GLPGPPG DG    RG+ GE+G  GLPGE G 
Sbjct: 513  KGEKGDVGIG-----PFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGM 567

Query: 523  RGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP------PGQQGTPGTQGLPGP 576
            RG   P+GPPG+PGPPG  G  G QG +G  G +GE G       PG+ G  G QG PGP
Sbjct: 568  RG---PQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGP 624

Query: 577  QGAIGPHGEKGPQGKPGLPGMPGS-------------DGPPGHPGKEGPPGTKGNQGPSG 623
             G  GP GEKG  G  G PG+PGS              GP GH G  GPPG +G  GP G
Sbjct: 625  SGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEG 684

Query: 624  PQGPLGYPGPRGVKG---VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRG 680
              GP G  G RG KG     GI GL G +G  G  G PG  G  G  G  GE+G PG  G
Sbjct: 685  RDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPG 744

Query: 681  EDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKG 740
              GP GP G+ GP G PGPPG  GE G+ G  GLPG PG +G  G  G  G PG  GE G
Sbjct: 745  PPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAG 804

Query: 741  ARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGL--PGPQGP 798
              G  G  G RGE+G  G +G+ G  G  G  G KG +G  GP G PG   L  P P+ P
Sbjct: 805  LPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMP 864

Query: 799  NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 858
             G  GPKG  G PG  G PG  G+ GE+G QG TGPPG  G  G  GA G  G  G  GH
Sbjct: 865  -GEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGH 923

Query: 859  ---PGPPGPPGEQGLPG---------------TAGKEGT------KGDPGPPGAPG---- 890
               PGP GPPG  G PG                AG+EG+      +GDPG PG PG    
Sbjct: 924  VGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGK 983

Query: 891  -KDGPAGLRGFPG-----------------------------ERGLPGTAGGPGLKGNEG 920
             KDG  GLRG PG                             +RG PG  G PG +G+ G
Sbjct: 984  GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPG 1043

Query: 921  --PSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGV 978
               +GPPGP+G PG++G+ GS G    PG PGPQGP G  G  G PGE+GP G  G   +
Sbjct: 1044 IGVAGPPGPSGPPGDKGSPGSRGL---PGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSL 1100

Query: 979  QGPVGL------------PGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGP 1026
              P  +            PGP G PG+ G  GDKG  G PG++GT+G KGE GPPG PGP
Sbjct: 1101 LSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGP 1160

Query: 1027 ---IGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGE 1083
                GP G  G  GADGE G +G QGH G  G  G  G  GPPG  G+ G  GP G +G 
Sbjct: 1161 PGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGS 1220

Query: 1084 TGDVGPMGPPGP---PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQG- 1139
             G  GP GP GP   PG  G  G  G DG  GPPG  G  G PG  G  G  G PG +G 
Sbjct: 1221 PGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGH 1280

Query: 1140 --EPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGP 1197
              + G  GPRGE G  G  GQ G PG  G  GPTG  GP+G  GP G  G PG PGE GP
Sbjct: 1281 TGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGP 1340

Query: 1198 RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGA 1257
             G  G KG +GE+G PG PG  GP G  G PG  G  G  G PG  G  G KG +GDPG 
Sbjct: 1341 SGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGI 1400

Query: 1258 IGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGD 1317
                G  GP G  G  G PG  G +G  G +G QG PG  G  GPPGP G PG PGLRG+
Sbjct: 1401 ---KGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGE 1457

Query: 1318 A-----------------------------------------GAKGEKGHPGLIGLIGPP 1336
            +                                         G  G  G  GL G  GP 
Sbjct: 1458 SPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPM 1517

Query: 1337 GEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPG-----GPPGLPGPAGPKG--AKGA 1389
            GE G  G  GL GP G  G KGE G  G  G  G G     GPPG+PG  G  G    G 
Sbjct: 1518 GEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGL 1577

Query: 1390 TGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQ 1421
             G  GP+GE G  G PG PGPPG   Q  P Q
Sbjct: 1578 PGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQ 1609



 Score =  710 bits (1832), Expect = 0.0
 Identities = 440/1070 (41%), Positives = 509/1070 (47%), Gaps = 191/1070 (17%)

Query: 252  PSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVL----EP 307
            P R+  P  Q  + +  T GE+                 G RGL G  G+P        P
Sbjct: 580  PGRVGAPGLQGERGEKGTRGEK-----------------GERGLDGFPGKPGDTGQQGRP 622

Query: 308  GML-VEGPPGPEGPAGLIGPPGI-------------QGNPGPVGDPGERGPPGRAGLPGS 353
            G   V GP G +G  G  GPPG+             QG PGP G  G  GPPG  G  G 
Sbjct: 623  GPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGP 682

Query: 354  DGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPG 413
            +G  GPPG   +   +     GD GP                 L L+GPPGP G  G PG
Sbjct: 683  EGRDGPPGLQGLRGKK-----GDMGPPGIP-----------GLLGLQGPPGPPGVPGPPG 726

Query: 414  PLGQPGSPGLKGESGDLGPQGPRGPQGL---TGPPGKAGRRGRAGADGARGMPGDPGVKG 470
            P G PG PG  G  G  GP GP GP G     GPPG  G +G  G  G  G+PG PG++G
Sbjct: 727  PGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRG 786

Query: 471  DRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKG 530
            + G  GL G PGEKG  G  GA G PG  GE G++G+ GE+G  GL G+ G +G  GP G
Sbjct: 787  EIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAG 846

Query: 531  PPGIPGPPGV----RGMDGPQGPKGSLGPQGEPGPPGQQGTPGT------QGLPGPQGAI 580
            PPG+PG   +      M G QGPKG  G  G PG PG QG PG        G PG +G  
Sbjct: 847  PPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQE 906

Query: 581  GPHGEKGPQGKPGLPG---MPGSDGPPGH---PGKEGPPGTKGNQGPSGPQGPLGYPGPR 634
            G HG  G  G PG PG    PG  GPPG    PG  G PG  G +G  G  G  G PGP 
Sbjct: 907  GAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPV 966

Query: 635  GVKGVDGIRGLKGHKGEKGEDGFPGFKGDIG--------------------------VKG 668
            G +G  G  GL G  G KG+DG PG +G  G                          VKG
Sbjct: 967  GPRGDPGAPGLPGPPG-KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKG 1025

Query: 669  DRGEVGVPGSRGE-----------DGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGY 717
            DRG  G+PGS G             GP GP G  G  G  G PG  G +G  G  G PG 
Sbjct: 1026 DRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGN 1085

Query: 718  PGRQGPKGSLGF---------------------------PGFPGASGEKGARGLSGKSGP 750
            PG +GP G  G                            PG PG  G+KG  G  G+ G 
Sbjct: 1086 PGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGT 1145

Query: 751  RGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGP 810
             G++G  GP G  GP G  G  G++G  G DG  G  G++G PG  G   F GP G PGP
Sbjct: 1146 EGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPG---FMGPPGNPGP 1202

Query: 811  PGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGL 870
            PG DG+ G  G  G  G  GK GPPGP G  G  G  GE G  G  G PGPPG PG+ G 
Sbjct: 1203 PGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGE 1262

Query: 871  PGTAGKEGTKGDPG------PPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 924
            PG  G EG +G PG        GAPG  G +G  G PG+ GLPG  G  G  G +GP GP
Sbjct: 1263 PGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGP 1322

Query: 925  ---------------PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP 969
                           PGP+G+PG++G+ G  G  G PG  GP+GPPG  GEKGVPG++G 
Sbjct: 1323 RGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGV 1382

Query: 970  IGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGP 1029
             G  G  G +G  G PG  G  G     G KG+ GDPG  G KG+ G  GP G PG  GP
Sbjct: 1383 PGKPGEPGFKGERGDPGIKGDKG---PPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGP 1439

Query: 1030 VGQPGAAGADGEPGARGP-----------QGHFGAKGD---------------EGTRGFN 1063
            VG PG  G  G PG RG            Q   G + +               + ++G  
Sbjct: 1440 VGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRP 1499

Query: 1064 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG-GV-GNLG 1121
            GPPGP G  GLPG +G  GE G  G  G  GP GP GP G  GA G  G PG G+ G +G
Sbjct: 1500 GPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMG 1559

Query: 1122 PPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1171
            PPG  G+PGE G     G PG+ GP+GE G  G  G PG PGPPG   P+
Sbjct: 1560 PPGIPGQPGEPGYAK-DGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPS 1608



 Score =  505 bits (1301), Expect = e-142
 Identities = 317/783 (40%), Positives = 369/783 (47%), Gaps = 125/783 (15%)

Query: 291  GPRGLKGEKGEPAVL-EPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAG 349
            G +G KGEKG+P +  EPG+  +G PG  GP G  GPPG +G  G  G PG  G PG  G
Sbjct: 865  GEQGPKGEKGDPGLPGEPGL--QGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPG 922

Query: 350  LPGSDGAPGPPGTSLMLPFRFGSGG--GDKGPVVAAQEAQAQAIL----QQARLALRGPP 403
              G+ G  GPPG S+  P   G+ G  G++G   AA E  +   +          L GPP
Sbjct: 923  HVGAPGPSGPPG-SVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPP 981

Query: 404  GPMGYTGRPGPLGQPGSPG-----------------------LKGESGDLGPQGPRGPQG 440
            G  G  G PG  G PG PG                       +KG+ G  G  G  G +G
Sbjct: 982  GK-GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRG 1040

Query: 441  -----LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGL 495
                 + GPPG +G  G  G+ G+RG+PG PG +G  G DG PG PGE+G  G  G   L
Sbjct: 1041 DPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSL 1100

Query: 496  ------------------PGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGP 537
                              PGPPG  G  G  G+ G  G PG  G  G  G  GPPG+PGP
Sbjct: 1101 LSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGP 1160

Query: 538  PGVRGMDGPQGPKGS------------------LGPQGEPGPPGQQGTPGTQGLPGPQGA 579
            PG+ G  G QG +G+                  +GP G PGPPG  G  G  G PG QG+
Sbjct: 1161 PGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGS 1220

Query: 580  IGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGV 639
             G  G  GPQG  GLPG+PG +G  G  GK GPPG  G  G  G  GP G  GP G KG 
Sbjct: 1221 PGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGH 1280

Query: 640  DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP 699
             G  G  G +GE G  G PG +G  G  GD G  G  G +G  GP G  G  G  G+PGP
Sbjct: 1281 TGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGP 1340

Query: 700  PGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGP 759
             G  G+KG  G  G PG PG  GP+G  G PG  G  G++G  G  G+ G +GERG  G 
Sbjct: 1341 SGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGI 1400

Query: 760  RGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGH 819
            +G +GP G  G+ G  G          PG +G  G  GP G PG  GP GPPG  G PG 
Sbjct: 1401 KGDKGPPGGKGQPGDPGI---------PGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGF 1451

Query: 820  PGQRG--------------EVGFQGKT------------------GPPGPPGVVGPQGAA 847
            PG RG              E+G Q +T                  G PGPPG  G  G  
Sbjct: 1452 PGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLP 1511

Query: 848  GETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLP 907
            G  GPMGE G PG  G  G  G  G  G+ G KGDPG PG        GLRG  G  G+P
Sbjct: 1512 GRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG-------VGLRGEMGPPGIP 1564

Query: 908  GTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGE- 966
            G  G PG    +G  G PGP G  G  G  G  GP GPPG+  P      A     PG  
Sbjct: 1565 GQPGEPGY-AKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNV 1623

Query: 967  KGP 969
            KGP
Sbjct: 1624 KGP 1626



 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 66/172 (38%), Positives = 74/172 (43%), Gaps = 36/172 (20%)

Query: 1308 PPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGE------------KGDRGLPGPQGSPG 1355
            PP  P  R       + G    I    P GE+GE            KGD G  GP G+PG
Sbjct: 452  PPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPG 511

Query: 1356 QKGEMGIPGASGPIGPG-----GPPGLPGPAGPKGAKGATGPGGPKGE---------KGV 1401
             KGE G  G  GP G G     G  GLPGP G  G+KG  G  G  GE         +G 
Sbjct: 512  PKGEKGDVGI-GPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGP 570

Query: 1402 QGPPGHPGPPGEVIQP-LPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1452
            QGPPG PGPPG V  P L  +  +K  R   G R +         G PG PG
Sbjct: 571  QGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLD--------GFPGKPG 614


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score =  905 bits (2340), Expect = 0.0
 Identities = 580/1381 (41%), Positives = 670/1381 (48%), Gaps = 262/1381 (18%)

Query: 287  EAAHGPRGLKGEKGEPAVLEPGML-VEGPPGPEGPAGLIGPPGIQGNPGPVGDPG----- 340
            E   GP G KG+ GEP +  PG     GPPG  G  G  G PGI G  GP G PG     
Sbjct: 69   EGPQGPPGQKGDTGEPGL--PGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCN 126

Query: 341  ----ERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAIL---- 392
                ERGP G  GLPG  G PGPPG    LP   G  G   G V        +       
Sbjct: 127  GTKGERGPLGPPGLPGFAGNPGPPG----LPGMKGDPGEILGHVPGMLLKGERGFPGIPG 182

Query: 393  ---QQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESG--DLGPQGPRGPQGLTGPPGK 447
                     L+GP GP G+TG PGP G PG PG KG+ G    GP+G +G QG++GPPG 
Sbjct: 183  TPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGV 242

Query: 448  AGR--------------RGRAGADGARGMPG--------------DPGVKGDRGFDGLPG 479
             G+              +G+ G  G +GMPG               PG  GD+G  G PG
Sbjct: 243  PGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPG 302

Query: 480  LPGEKGH---------RGDTGAQGLPGPPG---------EDGERGDDGEIGPRGLPGESG 521
             PGE G+         +G+ G  G PGPPG         E GERG  G  GPRG PG  G
Sbjct: 303  FPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKG 362

Query: 522  PRGLLGPKGPPGIPGP-------------------------PGVRGMDGPQGPKGSLGPQ 556
              GL G  GPPG+P P                         PG  G DG  GP GS GP 
Sbjct: 363  FPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPP 422

Query: 557  GEPG-----------PPGQQGTPGTQGLPGPQGAIGPHGEKGPQ----GKPGLPGMPGSD 601
            G+PG           PPG QG PG  G PG  G IG  G+KG         G  G PG  
Sbjct: 423  GQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQ 482

Query: 602  GPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH----------KGE 651
            GPPG  G  G PG KG++G  G  G  G PGP+G  G+ G  G KG           KG+
Sbjct: 483  GPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGD 542

Query: 652  KGEDGFPG------------------------FKGDIGVKGDRGE---VGVPGSRGEDGP 684
            KG+ GFPG                          G +G+KG+RG    VG PGSRG+ GP
Sbjct: 543  KGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGP 602

Query: 685  EGP-----------KGRTGPTGDPGPPGLMGEKGKLG-------------VPGLPGYPGR 720
             GP           KG+ G  G PG PGL G KG+ G             +PG PG+PG 
Sbjct: 603  PGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGP 662

Query: 721  QGPKGSLGFPGFPGASGEKGARGLSGKS--GPRGERGPTGPRGQRGPRGATGKSGAKGTS 778
            QG +G  G PG PG  GEKGA G  G    GP G +G  G  G  GP G  G+ G  G  
Sbjct: 663  QGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLP 722

Query: 779  GGDGPHGPPGERG--LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVG---FQGKTG 833
            G  G  G  GE G  LPG +G  G PG  G PG  G  G+PG PG+ G +G    QG  G
Sbjct: 723  GNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRG 782

Query: 834  PPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDG 893
             PGPPG+ G  G+ G  G     G PG  GPPG QG PG +G  G KG+ G PG PG D 
Sbjct: 783  EPGPPGLPGSVGSPGVPGI----GPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDM 838

Query: 894  PAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQG 953
            P G +G  G +GLPG  G  GL G  G  G PG  G PG +G  G  G  G PG PGP G
Sbjct: 839  P-GPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVG 897

Query: 954  PPGAAGEKG---VPGEKGPIGPTGRDGVQGPVGLPGPAGP---------PGVAGEDGDKG 1001
             PG  GEKG    PG  GP G  G  G +G VGLPG  G           G  G+ G+KG
Sbjct: 898  APGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKG 957

Query: 1002 EVGDPGQKGTKGNKGEHGPPGP------PGPIGPVGQPGAAGADGEPGARGPQGHFGAKG 1055
            ++G  G+KG++G+ G  G PG       PG  GP G PG +G  G PG  GP+G  G  G
Sbjct: 958  QIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMG 1017

Query: 1056 DEGT---RGFNGPPGPIGLQGLPGPSGEKGETGDVGP--MGPPGPPGPRGPAGPNGADGP 1110
              GT   +G  G PGP G  GLPG  G KGE G  GP  +G PG  G +G  G  G  G 
Sbjct: 1018 LPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGS 1077

Query: 1111 QGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG------------ESGQ 1158
             G  G  G++G PG  G PG  GSPG  G PG  G  GE+G+KG            E+G 
Sbjct: 1078 PGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGL 1137

Query: 1159 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGE------ 1212
            PG PGP GP G  G+ G  G PG  G  G+PG PG G P G  GAKGD+G  GE      
Sbjct: 1138 PGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFP-GFPGAKGDKGSKGEVGFPGL 1196

Query: 1213 ---PGQPGSPGPTGENGPPGPLGKRGPAGSPG--SEGRQGGKGAKGDPGAIGAPGKTGPV 1267
               PG PGS G  G  GPPGP G+ G  GSPG  +EG +G +G +G PG  G PG  GP 
Sbjct: 1197 AGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPP 1256

Query: 1268 G---------------------PAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPV 1306
            G                       GP G PG  G+ G+ GS G  G  G  G  G PG  
Sbjct: 1257 GLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQ 1316

Query: 1307 GPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGE----KGDRGLPGPQGSPGQKGEMGI 1362
            GP GLPGL+G  G +G++G PG  GL GPPG  G     KG+ GLPGP+G PG KG  G+
Sbjct: 1317 GPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGL 1376

Query: 1363 P------GASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQ 1416
            P      G +G +G  GPPG+PG  G  G KG  GP GP G +G  GPPG  G PG +  
Sbjct: 1377 PGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGP 1436

Query: 1417 P 1417
            P
Sbjct: 1437 P 1437



 Score =  894 bits (2310), Expect = 0.0
 Identities = 569/1386 (41%), Positives = 660/1386 (47%), Gaps = 294/1386 (21%)

Query: 290  HGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAG 349
            HG +G KGE+G P                G  G+IG PG+QG  GP G PG++G  G  G
Sbjct: 42   HGVKGQKGERGLP----------------GLQGVIGFPGMQGPEGPQGPPGQKGDTGEPG 85

Query: 350  LPGSDGAPGPPGTSLM-----LPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPG 404
            LPG+ G  GPPG S       LP   G  G    P +            +      GPPG
Sbjct: 86   LPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNG------TKGERGPLGPPG 139

Query: 405  PMGYTGRPGPLGQPGSPGLKGESGDL----------------------------GPQGPR 436
              G+ G PGP   PG PG+KG+ G++                            G QGP 
Sbjct: 140  LPGFAGNPGP---PGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPV 196

Query: 437  GPQGLTGPPGKAGRRGRAGADGARGM--PGDPGVKGDRGFDGLPGLP------------- 481
            GP G TGPPG  G  G  G  G  G+   G  G KGD+G  G PG+P             
Sbjct: 197  GPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFAT 256

Query: 482  -GEKGHRGDTGAQGL-----------PGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPK 529
             GEKG +G+ G QG+           PGP G+ G+ GD GE G  G PGE G  GL+G +
Sbjct: 257  KGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQ 316

Query: 530  GP------PGIPGPPGV------------RGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQ 571
            GP       G PGPPG+            RG  G  GP+G  GP+G PG PGQ G PG  
Sbjct: 317  GPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLP 376

Query: 572  GLPGPQGAIGPHGEK--------------GPQGKPGLPGMPGSDGPPGHPG--------K 609
             +PG  GA G  GE+              GP G+ GLPG PGS GPPG PG        +
Sbjct: 377  -VPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQ 435

Query: 610  EGPPGTKGNQGPSGPQGPLGYPGPRGVKG-------VDGIRGLKGHKGEKGEDGFPGFKG 662
             GPPG +G  G  G  G +G  G +G KG       +DG RG  G +G  GE GFP   G
Sbjct: 436  PGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFP---G 492

Query: 663  DIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPG-------LMGEKGKLGVPGLP 715
              G KGDRG  G  G  G  GP+G  G  G  G  G PG       L G+KG  G PG P
Sbjct: 493  QPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQP 552

Query: 716  GYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGP---------RGERGPTGPRGQRGPR 766
            G  GR G  G  G PG PG  G  G+ GL G+ GP         RG+ GP GP G  GP 
Sbjct: 553  GMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGY-GPA 611

Query: 767  GATGKSGAKGTSGGDGPHGPPGERG-------LPGPQGPNGFPGPKGPPGPPGKDGLPGH 819
            G  G  G  G  GG G  G PG +G       LPGP G  G PG  G PGP G  G PG 
Sbjct: 612  GPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGT 671

Query: 820  PGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 879
            PG+ G  G +G  G PG  G  GP G  G  G  G+ G PG PG PG  GLPG  G +G 
Sbjct: 672  PGRPGLPGEKGAVGQPG-IGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQ 730

Query: 880  KGDPGP--------------PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPP 925
            KG+PG               PG PG+ G  G+ G PGE G  G  G  G++G  GP G P
Sbjct: 731  KGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLP 790

Query: 926  GPAGSPGERGAA--GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKG--PIGPTGRDGVQGP 981
            G  GSPG  G    G+ GP G  G PG  GPPG  GEKG PG  G    GP G  G QG 
Sbjct: 791  GSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGL 850

Query: 982  VGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGE 1041
             G+ G +G PG+ G+ G  G  G PG KG  G  G  G PG PGP+G  G PG  G  G 
Sbjct: 851  PGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGF 910

Query: 1042 PGARGPQGHFGAKGDEGTRGFNGPPGPI---------------GLQGLPGPSGEKGETGD 1086
            PG+ GP+G  G KGD+G  G  G PG +               G +G  GP GEKG  GD
Sbjct: 911  PGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGD 970

Query: 1087 V---------GPMGPPGPPGPRGP---AGPNGADGPQGPPGGVGNLGPPGEKGEPGESGS 1134
                      G  G PG PGP+G    +G  GA G  GP G VG +G PG  GE G  G 
Sbjct: 971  PGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGI 1030

Query: 1135 PGIQGEPGVKGPRGERGEKGESGQP-----------------GEPGPPGPKGP------- 1170
            PG QG PG+ G +G +GEKG++G P                 G PG PG KG        
Sbjct: 1031 PGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIP 1090

Query: 1171 --TGDDGPKGNPGPVGFPGDPGPPGEGGPR---GQDGAKGDRGEDGEPGQPGSPGPTGEN 1225
               G  G KG+PG VG+PG PG PGE G +   G DG  G +GE G PG PG  GP G+ 
Sbjct: 1091 GMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQK 1150

Query: 1226 GPPGPLGKRGPAGS--------------PGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAG 1271
            G PG  G  G AG               PG++G +G KG  G PG  G+PG  G  G  G
Sbjct: 1151 GEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQG 1210

Query: 1272 PAGKPGPDGLRGLPGS--------VGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1323
              G PGP G  GLPGS         G +G  G  G  G PGP+GPPGLPG+ G  G KG 
Sbjct: 1211 FMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGN 1270

Query: 1324 KGHPGLIGL---------------------------IGPPGEQGEKGDRGLPGPQGSPGQ 1356
             G PG  G+                           +GPPG  G +G +GLPG QG  G 
Sbjct: 1271 PGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGD 1330

Query: 1357 KGEMGIPGASGPIGPGGP----------PGLPGPAGPKGAKGATGPGGPKGEKGVQGPPG 1406
            +G+ G+PGA G  GP GP          PGLPGP GP G KG  G  GPKG++GV G  G
Sbjct: 1331 QGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVG 1390

Query: 1407 HPGPPG 1412
             PGPPG
Sbjct: 1391 IPGPPG 1396



 Score =  801 bits (2068), Expect = 0.0
 Identities = 507/1161 (43%), Positives = 580/1161 (49%), Gaps = 171/1161 (14%)

Query: 446  GKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLP------GPP 499
            GK    G  G  G RG+PG  GV G  G  G  G  G  G +GDTG  GLP      GPP
Sbjct: 37   GKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPP 96

Query: 500  GEDGERGD---------DGEIGPRGLPGESGPRGLLGPKGPPGI------PGPPGVRGMD 544
            G  G  G+         DG  GP G+PG +G +G  GP GPPG+      PGPPG+ GM 
Sbjct: 97   GASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMK 156

Query: 545  GPQGPKGSLGP----QGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGS 600
            G  G      P    +GE G PG  GTPG  GLPG QG +GP G  GP G PG PG PG 
Sbjct: 157  GDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGE 216

Query: 601  DGPPGHPGKEGPPGTKGNQGPSGPQGPLGY-----------PGPRGVKGVDGIRGLKGHK 649
             G  G    +GP G KG+QG SGP G  G             G +G KG  G +G+ G  
Sbjct: 217  KGQMG-LSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPG-V 274

Query: 650  GEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED------GPEGPKGRTGPTGDPGPPGL- 702
            GEKGE G PG +G  G  GD+GE G PG  GE       G +GP+G  G  G PGPPG+ 
Sbjct: 275  GEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIV 334

Query: 703  -----MGEKGKLGVPGLPGYPGRQGPK-----------------GSLGFPGFPGASGEKG 740
                 +GEKG+ G PG PG  G  GPK                 G  G PGFPG  GEKG
Sbjct: 335  IGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKG 394

Query: 741  ARGLSGKS--GPRGERGPTGPRGQRGPRGATGKSGA-----KGTSGGDGPHGPPGERGLP 793
             RG  G S  GP G  G  GP G  GP G  G +        G  G  GP G PG+ G  
Sbjct: 395  DRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFI 454

Query: 794  GPQGP-------------NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGK------TGP 834
            G  G              +G+ GP GP GPPG+ G PG PG +G+ G  G+       GP
Sbjct: 455  GEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGP 514

Query: 835  PGPPGVVGPQGAAGETGPM-------GERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPG 887
             G PG++G  GA GE G         G++G PG PG PG  G  G+ G++G  G PGP G
Sbjct: 515  QGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKG 574

Query: 888  APGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPP--GPAGSPGERGAAGSGGPIGP 945
            +PG        G  GERG PG  G PG +G+ GP GPP  GPAG  G++G AG  G  G 
Sbjct: 575  SPGS------VGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGS 628

Query: 946  PGRPGPQ----------GPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGP-------- 987
            PG PGP+          GPPGA G  G PG  GP G  G  G  G  GLPG         
Sbjct: 629  PGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPG 688

Query: 988  ---AGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGP--VGQPGAAGADGEP 1042
                GPPG  G DG  G++G PG  G  G  G  G PG  G  G   VG PG  G  G P
Sbjct: 689  IGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLP 748

Query: 1043 GARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPP--GPPGPRG 1100
            G  G  G  G+ G  G  G +G  GP GLQG+ G  G  G  G VG  G P  GPPG RG
Sbjct: 749  GIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARG 808

Query: 1101 PAGPNGADGPQGPPGGVGNLGPPGEKG--EPGESGSPGIQGEPGVKGPRGERGEKGESGQ 1158
            P G  G  G  GPPG  G  G PG  G   PG  G  G QG PG+ G  G  G  G+ G 
Sbjct: 809  PPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGA 868

Query: 1159 PGEPGPPGPKGP---TGDDGPKGNPGPVGFPGDPGP------PGEGGPRGQDGAKGDRGE 1209
            PG PG PG KG     G  G  G+PGPVG PG PG       PG  GPRG  G KGD+G+
Sbjct: 869  PGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGD 928

Query: 1210 DGEPGQPGSPGPT------GENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGK 1263
             G PG+PGS          G+ G  G  G+ GP G  GS G  G  G  G  G  G PG+
Sbjct: 929  VGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQ 988

Query: 1264 TGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1323
             GP G  G +G PG  GL G  GSVG  G PG  G+ G PG  GP G PGL GD GAKGE
Sbjct: 989  PGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGE 1048

Query: 1324 KGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGE---MGIP---------GASGPIGP 1371
            KG  G  G IG PG +GEKGD+G+ G  GSPG+KGE   +GIP         G+ G +G 
Sbjct: 1049 KGQAGPPG-IGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGY 1107

Query: 1372 GGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVD 1431
             G PGLPG  G KG  G  G  G KGE G+ G PG  GP G+  +P    +P        
Sbjct: 1108 PGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIP-------- 1159

Query: 1432 GSRLMQEDEAIPTGGAPGSPG 1452
            GS   + +  +P  G PG PG
Sbjct: 1160 GSAGEKGEPGLPGRGFPGFPG 1180



 Score =  799 bits (2064), Expect = 0.0
 Identities = 518/1221 (42%), Positives = 596/1221 (48%), Gaps = 149/1221 (12%)

Query: 212  PGVQAAYESCEQKELECEG--GQRERPQNQ-QPHRAQRSPQQQPSRLHRPQNQEPQSQDP 268
            PGV    +  E+ +   +G  GQ+  P  Q  P   ++    +P    +P     + +  
Sbjct: 240  PGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKG 299

Query: 269  TPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLV-EGPPGPEGPAGLIGPP 327
            +PG   E     L+        GP+G KGE G P    PG+++  GP G +G  G  G P
Sbjct: 300  SPGFPGEPGYPGLI-----GRQGPQGEKGEAGPPG--PPGIVIGTGPLGEKGERGYPGTP 352

Query: 328  GIQGNPGPVGDPGERGPPGRAGLP--GSDGAPGPPG------------TSLMLPF-RFGS 372
            G +G PGP G PG  G PG  GLP  G  GAPG PG            TSL  P  R G 
Sbjct: 353  GPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGL 412

Query: 373  GGGDKGPVVAAQEAQAQAILQQARLALRGPPG---PMGYTGRPGPLGQPGSPGLKGES-- 427
             G    P    Q      I++       GPPG   P G  G+PG +G+ G  G KGES  
Sbjct: 413  PGPPGSPGPPGQPGYTNGIVE----CQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCL 468

Query: 428  --------GDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGV----------- 468
                    G  GPQGP G  G  G PG  G RG  G DG  G+PG  G            
Sbjct: 469  ICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKG 528

Query: 469  --------------KGDRGF---------------DGLPGLPGEKGHRGDTGAQGLPGPP 499
                          KGD GF               DG PGLPG KG  G  G +G  GPP
Sbjct: 529  EPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPP 588

Query: 500  GEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEP 559
            G  G  G  G+ GP G PG  GP G +G KG  G PG PG  G+ GP+G  G + P   P
Sbjct: 589  GGVGFPGSRGDTGPPGPPGY-GPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPL--P 645

Query: 560  GPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGK--EGPPGTKG 617
            GPPG +G PG+ G PGPQG      ++G  G PG PG+PG  G  G PG    GPPG KG
Sbjct: 646  GPPGAEGLPGSPGFPGPQG------DRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKG 699

Query: 618  NQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGED-----GFPGFKGDIGVKGDRGE 672
              G  G  GP G PG  G  G+ G  G++G KGE G       G PG  G  G  G++G 
Sbjct: 700  VDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGS 759

Query: 673  VGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLP-----GYPGRQGP---- 723
            +GVPG  GE G  GP G  G  G+PGPPGL G  G  GVPG+      G PG QGP    
Sbjct: 760  IGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLS 819

Query: 724  -----KGSLGFPGFPGAS-----GEKGARGL---SGKSGPRGERGPTGPRGQRGPRGATG 770
                 KG  GFPGFPG       G+KGA+GL   +G+SG  G  G  G  G  G  G+ G
Sbjct: 820  GPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKG 879

Query: 771  KSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQG 830
            + G  GT G  G  GP G  GLPG +G +GFPG  GP G PG  G  G  G  G+ G   
Sbjct: 880  EMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMD 939

Query: 831  KTGPPGPPGVVGPQGAAGETGPMGE---RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPG 887
            K       G  G QG  G+ GP+GE   RG PG PG PG+ G  G  G+ G KGDPG  G
Sbjct: 940  KVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISG 999

Query: 888  APGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGP--IGP 945
             PG  G  G +G  G  GLPGT G  G+ G  GP G PG  G  G +G  G  GP  IG 
Sbjct: 1000 TPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGI 1059

Query: 946  PGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGL---PGPAGPPGVAGEDGDKGE 1002
            PG  G +G  G AG  G PGEKG  G  G  G+ G  GL   PG  G PG  G  G+KG+
Sbjct: 1060 PGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGD 1119

Query: 1003 VGDPGQKGTKGNKGEHGPPGPPGPIGPVGQ---------PGAAGADGEPG--ARGPQGHF 1051
             G PG  G  G KGE G PG PGP GP GQ         PG+AG  GEPG   RG  G  
Sbjct: 1120 KGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFP 1179

Query: 1052 GAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPA--GPNGADG 1109
            GAKGD+G++G  G PG  G  G+PG  GE+G  G  GP G PG PG  G A  GP G  G
Sbjct: 1180 GAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRG 1239

Query: 1110 PQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKG 1169
            PQG PG  G  GP G  G PG  G  G +G PG  G  G  G KG+ G  G PG  G  G
Sbjct: 1240 PQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPG 1299

Query: 1170 PTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGP-------T 1222
             TG  G  G PG  GF G  G PG  G +G  G +G  G  G PG PG PGP        
Sbjct: 1300 ITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEP 1359

Query: 1223 GENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLR 1282
            G  GP GP G +G  G PG +G+QG  G  G PG  G PG  G  G  G  G  GP G R
Sbjct: 1360 GLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPR 1419

Query: 1283 GLPGSVGQQGRPGATGQAGPP 1303
            G PG  G  G PG+ G  G P
Sbjct: 1420 GFPGPPGPDGLPGSMGPPGTP 1440



 Score =  416 bits (1068), Expect = e-115
 Identities = 256/610 (41%), Positives = 310/610 (50%), Gaps = 85/610 (13%)

Query: 283  PPLEEAAHGPRGLKGEKGEPAVLEPGML----VEGPPGPEGPAGLIGPPGIQGNPGPVGD 338
            P  ++ A G  G+ G+ G P +  PG      + G PG +G  G++G PG  G+PGPVG 
Sbjct: 841  PKGDKGAQGLPGITGQSGLPGL--PGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGA 898

Query: 339  PGERGPPGRAGLPGSDGAPGPPGTS-----LMLPFR--------FGSGGGDKGPVVAAQE 385
            PG  G  G  G PGS G  G PG       + LP +         GS  G KG     ++
Sbjct: 899  PGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGD--QGEK 956

Query: 386  AQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLG---------PQGPR 436
             Q   I ++     RG PG  G  G+ G  GQPG PG KG+ G  G         P+G  
Sbjct: 957  GQIGPIGEKGS---RGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSV 1013

Query: 437  GPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKG--------------------DRGFDG 476
            G  GL G PG+ G  G  G  G+ G+PGD G KG                    D+G  G
Sbjct: 1014 GGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAG 1073

Query: 477  LPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPG 536
             PG PGEKG +G  G  G+PG PG  G  G  G  G  GLPGE G +GL G  G PG+ G
Sbjct: 1074 FPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKG 1133

Query: 537  PPGVRGMDGPQGP---KGSLGPQGEPGPPGQQGTPGT--QGLPGPQGAIGPHGEKGPQGK 591
              G+ G  GP GP   KG  G  G PG  G++G PG   +G PG  GA G  G KG  G 
Sbjct: 1134 EAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGF 1193

Query: 592  PGL---PGMPGSDG------PPGHPGKEGPPGTKGN--QGPSGPQGPLGYPG-------- 632
            PGL   PG+PGS G      PPG  G+ G PG+ G+  +GP G +GP G PG        
Sbjct: 1194 PGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPM 1253

Query: 633  -PRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRG---EVGVPGSRGEDGPEGPK 688
             P G+ G+DG++G KG+ G  G  G PG KGD G +G  G     G+ GS+G+ GP G  
Sbjct: 1254 GPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVP 1313

Query: 689  GRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL----GFPGFPGASGEKGARGL 744
            G  GP G PG  G+ G++G  GVPG  G PG  GP G      G PG PG  G  G +GL
Sbjct: 1314 GFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGL 1373

Query: 745  SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 804
             G  GP+G++G TG  G  GP G  G  GA G  G  GP GP G RG PGP GP+G PG 
Sbjct: 1374 QGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGS 1433

Query: 805  KGPPGPPGKD 814
             GPPG P  D
Sbjct: 1434 MGPPGTPSVD 1443



 Score =  256 bits (654), Expect = 1e-67
 Identities = 165/390 (42%), Positives = 186/390 (47%), Gaps = 57/390 (14%)

Query: 1116 GVGNLGPPGEKGEPGESGSPGIQGE---PGVKGPRGERGEKGESGQPGEPGPPGPKGPTG 1172
            G G     G KG+ GE G PG+QG    PG++GP G +G  G+ G  GEPG PG KG  G
Sbjct: 35   GCGKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRG 94

Query: 1173 DDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLG 1232
              G  G PG    PG PG PG+ GP G  G  G  G  GE G  G PG  G  G PGP G
Sbjct: 95   PPGASGYPGN---PGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPG 151

Query: 1233 KRGPAGSPGS----------EGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLR 1282
              G  G PG           +G +G  G  G PG  G PG  GPVGP G  G PGP G  
Sbjct: 152  LPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPP 211

Query: 1283 GLPGSVGQQGR--PGATGQAGPPGPVGPPGLPGL-----RGDAGAKGEKGHPGLIGLIGP 1335
            G PG  GQ G    G  G  G  G  GPPG+PG      +GD   KGEKG  G  G  G 
Sbjct: 212  GPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGM 271

Query: 1336 PGEQGEKGDRGLPGPQGSPGQ---KGEMGIP------------------GASGPIGPGGP 1374
            PG  GEKG+ G PGP+G PG+   KGE G P                  G  G  GP GP
Sbjct: 272  PG-VGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGP 330

Query: 1375 PGL---PGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQ---------M 1422
            PG+    GP G KG +G  G  GP+GE G +G PG PG PG    P+P Q          
Sbjct: 331  PGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGER 390

Query: 1423 PKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1452
             +K  R   G+ L          G PGSPG
Sbjct: 391  GEKGDRGFPGTSLPGPSGRDGLPGPPGSPG 420


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
            sapiens]
          Length = 1424

 Score =  895 bits (2312), Expect = 0.0
 Identities = 594/1412 (42%), Positives = 686/1412 (48%), Gaps = 271/1412 (19%)

Query: 291  GPRGLKGEKGEPAVL-EPGML----VEGPPGPEGPAG---------------LIGPPGIQ 330
            G +G KGEKG P     PG       EG PGP+GP G               + G PG  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 331  GNPGPVGDPGERGPPGRAGLPGSDGA------PGPPGTSLMLPFRFGSGG--GDKGPVVA 382
            G+PG  G PG  GP G  G+PG  G+      PG PGT L  P   G+ G  G KG    
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGT-LGYPGIPGAAGLKGQKGAPAK 161

Query: 383  AQEAQAQAILQQARLALRGPPGPMGYTGRPG---PLGQPGSPGLKGESGDLGPQGP---- 435
             ++ +  A   +    L G PGP G  G PG   P+G PG PG  G  G +GP+GP    
Sbjct: 162  EEDIELDA---KGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHM 218

Query: 436  ----------RGPQGLTGPPGKAGR--------------RGRAGADGA------------ 459
                      RG +GLTGPPG  G               +G  G  GA            
Sbjct: 219  GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGL 278

Query: 460  --------RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI 511
                    +G PGDPG++G  G DG+PG PG +G +G+   +G PG  GEDG +G  G+I
Sbjct: 279  PGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN---RGFPGLMGEDGIKGQKGDI 335

Query: 512  GP------------------RGLPGESGPRGLLGPKGP---PGIPGPPG-----VRGMDG 545
            GP                   G PG  GPRG  GP+GP   PG+PG PG     +RG  G
Sbjct: 336  GPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPG 395

Query: 546  PQGPKGSLGPQGEPGP-----PGQQGTPGTQGLPGPQGAIGPHGE----KGPQGKPGLPG 596
              G KGS G +G PG      PG  G  G+ GLPG  G  GP G+    KGP G  GLPG
Sbjct: 396  WPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPG 455

Query: 597  MPGSDGPPGHPGKEGPPGTKGNQGP--SGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGE 654
              GS G PG  G +G PG    Q P   GP G  G PG  GVKG+ G +G  G KG  G 
Sbjct: 456  YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515

Query: 655  DG---------FPGFKGDIGVKGDRGE-------VGVPGSRGEDGPEGPKGRTGPTGDPG 698
             G         FPG +GD G+KG++GE       VGVPG  G  G  G KG  G  G PG
Sbjct: 516  PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575

Query: 699  PPGLMGEKGKL------------GVPGLPGYPGRQGPKGSLGF-----PGFPGASGEKGA 741
              GL G KG+L            G PG PG PG  GP G  G+     PG  G  G  GA
Sbjct: 576  VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635

Query: 742  RGLSGKSGPRGER----------GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG 791
             G  G++GPRGE           GP GP G  GP+G  G  G+ G  G  G  GP GE G
Sbjct: 636  PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPG 695

Query: 792  LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP--------PGVVGP 843
            +PG   P G PGPKG  G PG  G  G PG+ GE G  GK G PG         PG  G 
Sbjct: 696  IPGIGFP-GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGT 754

Query: 844  QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE 903
             G  GE G  GE G  G PG PG  G PG  G +G +GDPG PG PG+ GP G R   G 
Sbjct: 755  PGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPG-RCIEGP 813

Query: 904  RGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSG--GPIGPPGRPGPQGPPGAAGEK 961
            RG  G  G  GLKG +G  G  GP G PG  G   SG  G  G PG PG QG  G  G++
Sbjct: 814  RGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQR 873

Query: 962  GVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPG------QKGTKGNK 1015
            G PG  G +GP G DGV G +G PG  GPPG  G  G  G+ G PG      Q+GT G K
Sbjct: 874  GYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAK 933

Query: 1016 GEHGPPGPPGP------IGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPI 1069
            GE G  G PGP      IG  G+PG  G  G PG            ++G RG  G PG  
Sbjct: 934  GEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPG------------EKGNRGVPGMPGLK 981

Query: 1070 GLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP 1129
            GL+GLPGP+G  G  GD+G  G PG PG RG  G  G  G  G  G  G LG PG  G P
Sbjct: 982  GLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRP 1041

Query: 1130 GESGSPGIQGE-----------PGVKGPRGERG---EKGESGQPGEPGPPGPKGPTGDDG 1175
            G  G  G+QG+           PG  GP G+ G   + G+ G+ G+PGPPG  GP G +G
Sbjct: 1042 GLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101

Query: 1176 PKGNPGPVGFPGDPGPPGEGGPRGQDGAKGD---RGEDGEPGQPGSPGPTG------ENG 1226
              G+PG  G PG PGP G+ G +G  G  G    RG  G PG PGSPGP G       +G
Sbjct: 1102 APGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDG 1161

Query: 1227 PPGPLGKRGPAG----SPGSEGRQGGKGAKGD---------PGAIGAPGKTGPVGPAGPA 1273
             PGP G++G  G     PG  G  G +GAKGD         PG  GA G  GP GP G  
Sbjct: 1162 IPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIE 1221

Query: 1274 GKPGPDGLRG--LPGSVGQQGRPGATGQAGPPGPVGPPG--LPGLRGDAGAKGE---KGH 1326
            G PGP GL G  +PG  G +G PG+ G  G PGP GPPG  + G++GD G+ G    KG 
Sbjct: 1222 GFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP 1281

Query: 1327 PGLIGLIGPPGEQGEKGDRGLPGP------QGSPGQKGEMGIPGASGPIGPGGPPGLPGP 1380
            PG  G +GPPG  G  G  GLPGP      QG PG KGE G PG  G IGP GP G  GP
Sbjct: 1282 PGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGP 1341

Query: 1381 AGPKG---------AKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVD 1431
             G +G           G+ GP G  GE G+QG PG PGPPG +    P   P K     D
Sbjct: 1342 PGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGK-----D 1396

Query: 1432 GSRLMQEDEAIPTG--GAPGSPGGLEEIFGSL 1461
            G    +     P G  G  GS G  E +F  L
Sbjct: 1397 G----KPGTPGPAGEKGNKGSKGEPESLFHQL 1424



 Score =  865 bits (2234), Expect = 0.0
 Identities = 550/1310 (41%), Positives = 641/1310 (48%), Gaps = 213/1310 (16%)

Query: 264  QSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGL 323
            + Q   P +EE+I   +   P    A GP+GL G  G P          GP GP GP G 
Sbjct: 153  KGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFP----------GPVGPPGPPGF 202

Query: 324  IGPPGIQGNPGPVGDPGER--GPPGRAGLPGSDGAPGPPGTSLML----PFRFGSGG--G 375
             G PG  G  GP G  GER  G  G  G+ G  G PGPPGT ++       R    G  G
Sbjct: 203  FGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKG 262

Query: 376  DKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPG------------- 422
            DKG +          +  ++  + +G PG  G  G+PG  G PG PG             
Sbjct: 263  DKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGL 322

Query: 423  -----LKGESGDLGPQGPRGP------------QGLTGPPGKAGRRGRAGADGARGMPGD 465
                 +KG+ GD+GP G RGP            +G  GPPG  G RG  G  G  G+PG 
Sbjct: 323  MGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGS 382

Query: 466  PGVK--GDRGFDGLPGLPGEKGHRGD--------------TGAQGLPGPPGEDGERGD-- 507
            PG    G RG  G PGL G KG RG                G+ GLPG PG  G  GD  
Sbjct: 383  PGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIV 442

Query: 508  -----------DGEIGPRGLPGESGPRGLLGP--------KGPPGIPGPPGVRGMDGPQG 548
                        G +G  G+PG  GP+G  G          GPPG+PG PG+ G+ G  G
Sbjct: 443  FRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPG 502

Query: 549  PKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKG----PQGKPGLPGMPGSDGPP 604
             +G+ G +G PG PG  G PG  G PG QG  G  GEKG    P+G+ G+PG PG  G P
Sbjct: 503  RQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQP 562

Query: 605  GHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF--KG 662
            G  G +G PGT G +G  GP+G L   G +G +G  G  G  G  G  G  G PG+  +G
Sbjct: 563  GRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQG 622

Query: 663  DIGVKGDRGEVGVPGSRGEDGPEG----------PKGRTGPTGDPGP---PGLMGEKGKL 709
            + G++G +G  G PG  GE GP G          P G  GP G PGP   PG+ G  GK 
Sbjct: 623  EPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKC 682

Query: 710  GVPGLPG-----------YPGRQGPKGSLGFPGFPGA---SGEKGARGLSGKSGPRGERG 755
            G PGLPG           +PG  GPKG  GFPG  G+    G+ G  GL GK G  G +G
Sbjct: 683  GDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKG 742

Query: 756  ------PTGPR--GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP 807
                  P GP   G  G RG +G+ G  G  G  G  G PG  GL GP+G  G PGP G 
Sbjct: 743  EPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGE 802

Query: 808  PGPPGK--------DGLPGHPGQRGEVGFQGKTGPPGPPGVVG--PQGAAGETGPMGERG 857
             GPPG+         GLPG  G +G+ G +GKTGP G PG+ G    G  GETG  G  G
Sbjct: 803  QGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPG 862

Query: 858  HPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKG 917
            H G  GP G++G PG         +PG  G PG+DG  G+ GFPG  G PG  G PG  G
Sbjct: 863  HQGEMGPLGQRGYPG---------NPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPG 913

Query: 918  NEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP------GPQGPPGAAGEKGVPGEKGPIG 971
              G  G PG  G  G  GA G  G  G PG        G +G PG  G  G PGEKG  G
Sbjct: 914  QRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRG 973

Query: 972  PTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVG 1031
              G  G++G  GLPGPAGPPG  G+ G  G  G+PG +G  G+ G  G PG  G  G +G
Sbjct: 974  VPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLG 1033

Query: 1032 QPGAAGADGEPGARGPQGHFGAKG-DEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPM 1090
             PG AG  G PG  G QG  G  G  EGTR   GPPGP G  GLPG  G+KGE      M
Sbjct: 1034 FPGRAGRPGLPGIHGLQGDKGEPGYSEGTRP--GPPGPTGDPGLPGDMGKKGE------M 1085

Query: 1091 GPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKG---------EPGESGSPGIQGEP 1141
            G PGPPG  GPAGP GA G  G PG  G  GP G+ G          PG  G PG+ G P
Sbjct: 1086 GQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFP 1145

Query: 1142 GVKGPRGERGEKGESGQPGEPG----------PPGPKGPTGDDGPKGNPGPVGFPGDPGP 1191
            G  GP G RG++G  G PG  G          PPGP+G  G  G KG+ G  GFPG PG 
Sbjct: 1146 GSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGR 1205

Query: 1192 PGEGGPRGQDGAKGDRGEDGEPGQPGS--PGPTGENGPPGPLGKRG---PAGSPGSE--G 1244
             G  G  G  G  G  G  G PG PG+  PG TG  GPPG  G  G   P G PGS   G
Sbjct: 1206 KGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIG 1265

Query: 1245 RQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL---------RGLPGSVGQQGRPG 1295
             +G KG+ G PG  G PG  G +GP G  G PG  GL         +G PG  G++G PG
Sbjct: 1266 IKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG 1325

Query: 1296 ATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPG 1355
              G  GPPGP+GP G PG+RGD         PG + +I  PG  G       PG  G PG
Sbjct: 1326 FLGSIGPPGPIGPKGPPGVRGD---------PGTLKIISLPGSPGP------PGTPGEPG 1370

Query: 1356 QKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPP 1405
             +GE G PG  G +GP GP G P   G  G  G  GP G KG KG +G P
Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKP---GKDGKPGTPGPAGEKGNKGSKGEP 1417



 Score =  716 bits (1849), Expect = 0.0
 Identities = 453/1076 (42%), Positives = 526/1076 (48%), Gaps = 134/1076 (12%)

Query: 263  PQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAG 322
            PQ     PG        S  P L  A   P GLKG KGE     PG    G PG  G AG
Sbjct: 370  PQGPSGPPGVPGS--PGSSRPGLRGAPGWP-GLKGSKGERG--RPGKDAMGTPGSPGCAG 424

Query: 323  LIGPPGIQGNPGPVGD-------PGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGG 375
              G PG  G PGP GD       PG+ G PG  G PG  G  GP G   +L  +     G
Sbjct: 425  SPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPG 484

Query: 376  DKG-PVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGS---PGLKGESGDL- 430
              G P +           +Q    L+G PG  G TG PG  G PG+   PGLKGE G+  
Sbjct: 485  PPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETL 544

Query: 431  ---GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG---VKGDRGFDGLPGLPGEK 484
               G  G  G  GL G PG+ G  G  G  G +G+PG  G   + G++G  G PG PG  
Sbjct: 545  QPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSP 604

Query: 485  GHRGDTGAQGLPG--PPGEDGERGDDGEIGPRGLPGESGPRGLLGPK----GPPGIPGPP 538
            G  G  G  G PG  P GE G +G  G  G  G PGE+GPRG L       GPPG PGPP
Sbjct: 605  GSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664

Query: 539  GVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT--------------QGLPGPQGAIGPHG 584
            G  G  GP G  GSLG  G+PG PG  G PG               QG PG +G++G  G
Sbjct: 665  GHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPG 724

Query: 585  EKGPQGKPGLPGMPGSDGPPG--HPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGI 642
            + G  G PG PG+PG+ G P    PG  G PG  G +G SG  G +G PG  G+ G  G 
Sbjct: 725  KMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGN 784

Query: 643  RGLKGHKGEKGEDGFPGFKGDIG--VKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPP 700
             GL G +G+ G+ G PG +G  G  ++G RG  G+PG  G  G +G +G+TGP GDPG P
Sbjct: 785  EGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIP 844

Query: 701  GL--MGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTG 758
            GL   G  G+ G PG+PG+ G  GP G  G+PG PG  G  G  G+ G  G  G  GP G
Sbjct: 845  GLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPG 904

Query: 759  PRGQRGP---RGATGKSGAKGTSGGDGPHGPPGERGLPGPQ------GPNGFPGPKGPPG 809
            P G  G    RG+ G  G KG  G  G  G  G++G PGP       G  G PG KG  G
Sbjct: 905  PPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAG 964

Query: 810  PPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQG 869
             PG+ G  G PG  G  G +G  GP GPPG   P+G  G TG  GE G  G PG  G  G
Sbjct: 965  NPGEKGNRGVPGMPGLKGLKGLPGPAGPPG---PRGDLGSTGNPGEPGLRGIPGSMGNMG 1021

Query: 870  LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGL--------PGTAGGPGLKGNEGP 921
            +PG+ GK GT G PG  G PG  G  GL+G  GE G         PG  G PGL G+ G 
Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGK 1081

Query: 922  SGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGP 981
             G  G  G PG  G AG  G  G PG PG  G PG  G+ G  G KG +GP G   ++GP
Sbjct: 1082 KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPG---IRGP 1138

Query: 982  VGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE-HGPPGPPGPIGPVGQPGAAGADG 1040
             GLPG  G PG  G  GD+G  G PG  G KG  G    PPGP G  G  G  G  GA G
Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG 1198

Query: 1041 EPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQG--LPGPSGEKGETGDVGPMGPPGPPGP 1098
             PG  G +G  G  G  G  G  G PGP GL G  +PG +G +G  G  G  G PGPPGP
Sbjct: 1199 FPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGP 1258

Query: 1099 --------RGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGER 1150
                    +G  G  G  GP+GPPG  G++GPPG  G PG  G PG +G+PG +G  G +
Sbjct: 1259 PGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVK 1318

Query: 1151 GEKGESG---------------------------------QPGEPGPPGPKGPTGDDGPK 1177
            GEKG  G                                  PG PG P            
Sbjct: 1319 GEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTP------------ 1366

Query: 1178 GNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGK 1233
            G PG  G PG PGPPG  GP       G RG+ G+ G+PG+PGP GE G  G  G+
Sbjct: 1367 GEPGMQGEPGPPGPPGNLGP------CGPRGKPGKDGKPGTPGPAGEKGNKGSKGE 1416



 Score =  368 bits (945), Expect = e-101
 Identities = 255/627 (40%), Positives = 279/627 (44%), Gaps = 122/627 (19%)

Query: 936  AAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP---PG 992
            AA  G      G+    G  G  GEKG P   GP G  G+ G  GP GLPGP GP   PG
Sbjct: 26   AASKGCVCKDKGQCFCDGAKGEKGEKGFP---GPPGSPGQKGFTGPEGLPGPQGPKGFPG 82

Query: 993  VAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGE---PGARGPQG 1049
            + G  G KG  G  G  G  G+ G  G PG  GP G VG PG +G+ GE   PG  G  G
Sbjct: 83   LPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLG 142

Query: 1050 HFGAKGDEGTRGFNGPP-----------GPIGLQGLPGPSGEKGETGDVGPMGPPGPP-- 1096
            + G  G  G +G  G P           G  GL G PGP G  G  G  GP+GPPGPP  
Sbjct: 143  YPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGF 202

Query: 1097 -------GPRGP--------------AGPNGADGPQGPPGGV------------------ 1117
                   GPRGP               G  G  GP GPPG V                  
Sbjct: 203  FGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKG 262

Query: 1118 -----GNLGPPGEKGEPGES--------GSPGIQGEP---GVKGPRGERGEKGESGQPGE 1161
                 G  GPPG  G PGES        G PG+QG+P   GV G  G  G KG  G PG 
Sbjct: 263  DKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGL 322

Query: 1162 PGPPGPKGPTGDDGPKGNPGPVGF------PGDPGPPGEGGPRGQDGAKGDRGEDGEPGQ 1215
             G  G KG  GD GP G  GP  +       GD G PG  GPRG  G +G  G  G PG 
Sbjct: 323  MGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGS 382

Query: 1216 PGS--PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA 1273
            PGS  PG  G  G PG  G +G  G PG +      G  G PG  G+PG  G  GP GP 
Sbjct: 383  PGSSRPGLRGAPGWPGLKGSKGERGRPGKD----AMGTPGSPGCAGSPGLPGSPGPPGPP 438

Query: 1274 G----KPGPDGLRGLPGSVGQQGRPGATGQAGP-----------PGPVGPPGLPGLRGDA 1318
            G    + GP G  GLPG +G  G PG  G  G            PGP G PGLPGL G  
Sbjct: 439  GDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVK 498

Query: 1319 GAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGE----------MGIPGASGP 1368
            G  G +G  GL G  G PG  G  G  G PG QG PG KGE          +G+PG  G 
Sbjct: 499  GIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGL 558

Query: 1369 IGPGGPPGLPGPAGPKGAKGATGPGGP---KGEKGVQGPPGHPGPPGEVIQPLPIQMPKK 1425
             G  G  GL G  G  G KG  GP G     GEKG QGPPG PG PG    P P      
Sbjct: 559  RGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPG---SPGPAGPAGP 615

Query: 1426 TRRSVDGSRLMQEDEAIPTGGAPGSPG 1452
                  G   +Q  + +P  GAPG PG
Sbjct: 616  PGYGPQGEPGLQGTQGVP--GAPGPPG 640



 Score =  315 bits (807), Expect = 2e-85
 Identities = 206/513 (40%), Positives = 244/513 (47%), Gaps = 84/513 (16%)

Query: 259  QNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGML-VEGPPGP 317
            + ++    +P P E   ++     P L+  A  P G KG +G P +  PG+  ++G PGP
Sbjct: 933  KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP-GEKGNRGVPGM--PGLKGLKGLPGP 989

Query: 318  EGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--- 374
             GP G  G  G  GNPG   +PG RG PG  G  G  G+ G  GT L  P R G  G   
Sbjct: 990  AGPPGPRGDLGSTGNPG---EPGLRGIPGSMGNMGMPGSKGKRGT-LGFPGRAGRPGLPG 1045

Query: 375  -----GDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGD 429
                 GDKG    ++  +             GPPGP G  G PG +G+ G  G  G  G 
Sbjct: 1046 IHGLQGDKGEPGYSEGTRP------------GPPGPTGDPGLPGDMGKKGEMGQPGPPGH 1093

Query: 430  LGPQGPRGPQGLTGPPG---KAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGH 486
            LGP GP G  G  G PG   K G  G  G  G +G+ G PG++G  G  G PG PG  G 
Sbjct: 1094 LGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGI 1153

Query: 487  RGDTGAQGLPGPPGEDGE-------------------RGDDGEIGPRGLPGESGPRGLLG 527
            RGD G  G+PGP GE GE                   +GD G  G  GLPG  G  G  G
Sbjct: 1154 RGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAG 1213

Query: 528  PKGPPGI---PGPPG-----VRGMDGPQGPKGSLGPQGEPGPPGQQGT--------PGTQ 571
            P+GP GI   PGPPG     + G  G +GP GS G  G PGPPG  G+         G+ 
Sbjct: 1214 PRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSM 1273

Query: 572  GLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQG---------PS 622
            G PGP+G  G  G+ GP G+ G PG PG  GP G PG +G PG KG +G         P 
Sbjct: 1274 GHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPP 1333

Query: 623  GPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED 682
            GP GP G PG RG  G   I  L G  G  G  G PG          +GE G PG  G  
Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGM---------QGEPGPPGPPGNL 1384

Query: 683  GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLP 715
            GP GP+G+ G  G PG PG  GEKG  G  G P
Sbjct: 1385 GPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEP 1417


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
            sapiens]
          Length = 1494

 Score =  894 bits (2311), Expect = 0.0
 Identities = 580/1363 (42%), Positives = 670/1363 (49%), Gaps = 260/1363 (19%)

Query: 291  GPRGLKGEKGEPAVL-EPGML----VEGPPGPEGPAG---------------LIGPPGIQ 330
            G +G KGEKG P     PG       EG PGP+GP G               + G PG  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 331  GNPGPVGDPGERGPPGRAGLPGSDGA------PGPPGTSLMLPFRFGSGG--GDKGPVVA 382
            G+PG  G PG  GP G  G+PG  G+      PG PGT L  P   G+ G  G KG    
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGT-LGYPGIPGAAGLKGQKGAPAK 161

Query: 383  AQEAQAQAILQQARLALRGPPGPMGYTGRPG---PLGQPGSPGLKGESGDLGPQGP---- 435
             ++ +  A   +    L G PGP G  G PG   P+G PG PG  G  G +GP+GP    
Sbjct: 162  EEDIELDA---KGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHM 218

Query: 436  ----------RGPQGLTGPPGKAGR--------------RGRAGADGA------------ 459
                      RG +GLTGPPG  G               +G  G  GA            
Sbjct: 219  GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGL 278

Query: 460  --------RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI 511
                    +G PGDPG++G  G DG+PG PG +G +G+   +G PG  GEDG +G  G+I
Sbjct: 279  PGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN---RGFPGLMGEDGIKGQKGDI 335

Query: 512  GP------------------RGLPGESGPRGLLGPKGP---PGIPGPPG-----VRGMDG 545
            GP                   G PG  GPRG  GP+GP   PG+PG PG     +RG  G
Sbjct: 336  GPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPG 395

Query: 546  PQGPKGSLGPQGEPGP-----PGQQGTPGTQGLPGPQGAIGPHGE----KGPQGKPGLPG 596
              G KGS G +G PG      PG  G  G+ GLPG  G  GP G+    KGP G  GLPG
Sbjct: 396  WPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPG 455

Query: 597  MPGSDGPPGHPGKEGPPGTKGNQGP--SGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGE 654
              GS G PG  G +G PG    Q P   GP G  G PG  GVKG+ G +G  G KG  G 
Sbjct: 456  YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515

Query: 655  DG---------FPGFKGDIGVKGDRGE-------VGVPGSRGEDGPEGPKGRTGPTGDPG 698
             G         FPG +GD G+KG++GE       VGVPG  G  G  G KG  G  G PG
Sbjct: 516  PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575

Query: 699  PPGLMGEKGKL------------GVPGLPGYPGRQGPKGSLGF-----PGFPGASGEKGA 741
              GL G KG+L            G PG PG PG  GP G  G+     PG  G  G  GA
Sbjct: 576  VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635

Query: 742  RGLSGKSGPRGER----------GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG 791
             G  G++GPRGE           GP GP G  GP+G  G  G+ G  G  G  GP GE G
Sbjct: 636  PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPG 695

Query: 792  LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP--------PGVVGP 843
            +PG   P G PGPKG  G PG  G  G PG+ GE G  GK G PG         PG  G 
Sbjct: 696  IPGIGFP-GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGT 754

Query: 844  QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE 903
             G  GE G  GE G  G PG PG  G PG  G +G +GDPG PG PG+ GP G R   G 
Sbjct: 755  PGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPG-RCIEGP 813

Query: 904  RGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSG--GPIGPPGRPGPQGPPGAAGEK 961
            RG  G  G  GLKG +G  G  GP G PG  G   SG  G  G PG PG QG  G  G++
Sbjct: 814  RGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQR 873

Query: 962  GVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPG------QKGTKGNK 1015
            G PG  G +GP G DGV G +G PG  GPPG  G  G  G+ G PG      Q+GT G K
Sbjct: 874  GYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAK 933

Query: 1016 GEHGPPGPPGP------IGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPI 1069
            GE G  G PGP      IG  G+PG  G  G PG            ++G RG  G PG  
Sbjct: 934  GEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPG------------EKGNRGVPGMPGLK 981

Query: 1070 GLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP 1129
            GL+GLPGP+G  G  GD+G  G PG PG RG  G  G  G  G  G  G LG PG  G P
Sbjct: 982  GLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRP 1041

Query: 1130 GESGSPGIQGE-----------PGVKGPRGERG---EKGESGQPGEPGPPGPKGPTGDDG 1175
            G  G  G+QG+           PG  GP G+ G   + G+ G+ G+PGPPG  GP G +G
Sbjct: 1042 GLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101

Query: 1176 PKGNPGPVGFPGDPGPPGEGGPRGQDGAKGD---RGEDGEPGQPGSPGPTG------ENG 1226
              G+PG  G PG PGP G+ G +G  G  G    RG  G PG PGSPGP G       +G
Sbjct: 1102 APGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDG 1161

Query: 1227 PPGPLGKRGPAG----SPGSEGRQGGKGAKGD---------PGAIGAPGKTGPVGPAGPA 1273
             PGP G++G  G     PG  G  G +GAKGD         PG  GA G  GP GP G  
Sbjct: 1162 IPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIE 1221

Query: 1274 GKPGPDGLRG--LPGSVGQQGRPGATGQAGPPGPVGPPG--LPGLRGDAGAKGE---KGH 1326
            G PGP GL G  +PG  G +G PG+ G  G PGP GPPG  + G++GD G+ G    KG 
Sbjct: 1222 GFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP 1281

Query: 1327 PGLIGLIGPPGEQGEKGDRGLPGP------QGSPGQKGEMGIPGASGPIGPGGPPGLPGP 1380
            PG  G +GPPG  G  G  GLPGP      QG PG KGE G PG  G IGP GP G  GP
Sbjct: 1282 PGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGP 1341

Query: 1381 AGPKG---------AKGATGPGGPKGEKGVQGPPGHPGPPGEV 1414
             G +G           G+ GP G  GE G+QG PG PGPPG +
Sbjct: 1342 PGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNL 1384



 Score =  877 bits (2267), Expect = 0.0
 Identities = 556/1317 (42%), Positives = 647/1317 (49%), Gaps = 201/1317 (15%)

Query: 264  QSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGL 323
            + Q   P +EE+I   +   P    A GP+GL G  G P          GP GP GP G 
Sbjct: 153  KGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFP----------GPVGPPGPPGF 202

Query: 324  IGPPGIQGNPGPVGDPGER--GPPGRAGLPGSDGAPGPPGTSLML----PFRFGSGG--G 375
             G PG  G  GP G  GER  G  G  G+ G  G PGPPGT ++       R    G  G
Sbjct: 203  FGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKG 262

Query: 376  DKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPG------------- 422
            DKG +          +  ++  + +G PG  G  G+PG  G PG PG             
Sbjct: 263  DKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGL 322

Query: 423  -----LKGESGDLGPQGPRGP------------QGLTGPPGKAGRRGRAGADGARGMPGD 465
                 +KG+ GD+GP G RGP            +G  GPPG  G RG  G  G  G+PG 
Sbjct: 323  MGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGS 382

Query: 466  PGVK--GDRGFDGLPGLPGEKGHRGD--------------TGAQGLPGPPGEDGERGD-- 507
            PG    G RG  G PGL G KG RG                G+ GLPG PG  G  GD  
Sbjct: 383  PGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIV 442

Query: 508  -----------DGEIGPRGLPGESGPRGLLGP--------KGPPGIPGPPGVRGMDGPQG 548
                        G +G  G+PG  GP+G  G          GPPG+PG PG+ G+ G  G
Sbjct: 443  FRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPG 502

Query: 549  PKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKG----PQGKPGLPGMPGSDGPP 604
             +G+ G +G PG PG  G PG  G PG QG  G  GEKG    P+G+ G+PG PG  G P
Sbjct: 503  RQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQP 562

Query: 605  GHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF--KG 662
            G  G +G PGT G +G  GP+G L   G +G +G  G  G  G  G  G  G PG+  +G
Sbjct: 563  GRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQG 622

Query: 663  DIGVKGDRGEVGVPGSRGEDGPEG----------PKGRTGPTGDPGP---PGLMGEKGKL 709
            + G++G +G  G PG  GE GP G          P G  GP G PGP   PG+ G  GK 
Sbjct: 623  EPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKC 682

Query: 710  GVPGLPG-----------YPGRQGPKGSLGFPGFPGA---SGEKGARGLSGKSGPRGERG 755
            G PGLPG           +PG  GPKG  GFPG  G+    G+ G  GL GK G  G +G
Sbjct: 683  GDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKG 742

Query: 756  ------PTGPR--GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP 807
                  P GP   G  G RG +G+ G  G  G  G  G PG  GL GP+G  G PGP G 
Sbjct: 743  EPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGE 802

Query: 808  PGPPGK--------DGLPGHPGQRGEVGFQGKTGPPGPPGVVG--PQGAAGETGPMGERG 857
             GPPG+         GLPG  G +G+ G +GKTGP G PG+ G    G  GETG  G  G
Sbjct: 803  QGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPG 862

Query: 858  HPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKG 917
            H G  GP G++G PG         +PG  G PG+DG  G+ GFPG  G PG  G PG  G
Sbjct: 863  HQGEMGPLGQRGYPG---------NPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPG 913

Query: 918  NEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP------GPQGPPGAAGEKGVPGEKGPIG 971
              G  G PG  G  G  GA G  G  G PG        G +G PG  G  G PGEKG  G
Sbjct: 914  QRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRG 973

Query: 972  PTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVG 1031
              G  G++G  GLPGPAGPPG  G+ G  G  G+PG +G  G+ G  G PG  G  G +G
Sbjct: 974  VPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLG 1033

Query: 1032 QPGAAGADGEPGARGPQGHFGAKG-DEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPM 1090
             PG AG  G PG  G QG  G  G  EGTR   GPPGP G  GLPG  G+KGE      M
Sbjct: 1034 FPGRAGRPGLPGIHGLQGDKGEPGYSEGTRP--GPPGPTGDPGLPGDMGKKGE------M 1085

Query: 1091 GPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKG---------EPGESGSPGIQGEP 1141
            G PGPPG  GPAGP GA G  G PG  G  GP G+ G          PG  G PG+ G P
Sbjct: 1086 GQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFP 1145

Query: 1142 GVKGPRGERGEKGESGQPGEPG----------PPGPKGPTGDDGPKGNPGPVGFPGDPGP 1191
            G  GP G RG++G  G PG  G          PPGP+G  G  G KG+ G  GFPG PG 
Sbjct: 1146 GSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGR 1205

Query: 1192 PGEGGPRGQDGAKGDRGEDGEPGQPGS--PGPTGENGPPGPLGKRG---PAGSPGSE--G 1244
             G  G  G  G  G  G  G PG PG+  PG TG  GPPG  G  G   P G PGS   G
Sbjct: 1206 KGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIG 1265

Query: 1245 RQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL---------RGLPGSVGQQGRPG 1295
             +G KG+ G PG  G PG  G +GP G  G PG  GL         +G PG  G++G PG
Sbjct: 1266 IKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG 1325

Query: 1296 ATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPG 1355
              G  GPPGP+GP G PG+RGD G       PG  G  G PGE G +G+ G PGP G+ G
Sbjct: 1326 FLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLG 1385

Query: 1356 QKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1412
              G  G PG        G PG PGPAG KG KG+ G  GP G  G+ G  G  G  G
Sbjct: 1386 PCGPRGKPGKD------GKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSG 1436



 Score =  831 bits (2146), Expect = 0.0
 Identities = 509/1147 (44%), Positives = 580/1147 (50%), Gaps = 97/1147 (8%)

Query: 291  GPRGLKGEKGEPAVLEPGMLVE-----------GPPGPEG---PAGLIGPPGIQGNPGPV 336
            G +G KG+ G P    P    +           GPPGP G   P G  GPPG+ G+PG  
Sbjct: 327  GIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGS- 385

Query: 337  GDPGERGPPGRAGLPGSDGAPGPPGTSLM-LPFRFGSGGGDKGPVVAAQEAQAQAILQQA 395
              PG RG PG  GL GS G  G PG   M  P   G  G    P           I+ + 
Sbjct: 386  SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFR- 444

Query: 396  RLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPR--GPQGLTGPPGKAGRRGR 453
                +GPPG  G  G  G  G PG  G KGE G L  Q P   GP GL G PG  G +G 
Sbjct: 445  ----KGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGI 500

Query: 454  AGADGARGMPGDPGVKGDRGFDGLPGLPGE------KGHRGDT-GAQGLPGPPGEDGERG 506
             G  GA G+ G PG  G+ G  G PG PG       KG +G+T   +G  G PG+ G RG
Sbjct: 501  PGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRG 560

Query: 507  DDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQ-- 564
              G  G  G+PG  G +GL GPKG   + G  G +G  G  G  GS GP G  GPPG   
Sbjct: 561  QPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGP 620

Query: 565  QGTPGTQGLPGPQGAIGPHGEKGPQGKPGL----PGMPGSDGPPGHPGKEGPPGTKGNQG 620
            QG PG QG  G  GA GP GE GP+G+  +    PG PG  GPPGHPG +GPPG  G+ G
Sbjct: 621  QGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLG 680

Query: 621  PSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRG 680
              G  G    PGP G  G+ GI G  G  G KG+ GFPG KG +G  G  GE G+PG  G
Sbjct: 681  KCGDPG---LPGPDGEPGIPGI-GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPG 736

Query: 681  EDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKG 740
              G +G      P G PG PG  GE+G  G  G  G PG  G       PG PG  G  G
Sbjct: 737  LPGAKGEPAVAMP-GGPGTPGFPGERGNSGEHGEIGLPGLPG------LPGTPGNEGLDG 789

Query: 741  ARGLSGKSGPRGERGPTGP--RGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGP 798
             RG  G+ GP GE+GP G    G RG +G  G +G KG  G  G  GP G+ G+PG    
Sbjct: 790  PRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDR- 848

Query: 799  NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP---------PGVVGPQGAAGE 849
            +GFPG  G PG PG  G  G  GQRG  G  G  GPPG          PG +GP G  G 
Sbjct: 849  SGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGN 908

Query: 850  TGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP---GKDGPAGLRGFPGERGL 906
             G  G+RG PG PG  G++G PG  G++G KG+PGP       G  G  GL+GF G  G 
Sbjct: 909  PGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGE 968

Query: 907  PGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGE 966
             G  G PG+ G +G  G PGPAG PG RG  GS    G PG PG +G PG+ G  G+PG 
Sbjct: 969  KGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS---TGNPGEPGLRGIPGSMGNMGMPGS 1025

Query: 967  KGPIGPTGRDGVQGPVGLPGPAGPPGVAGE--------DGDKGEVGDPGQKGTKGNKGEH 1018
            KG  G  G  G  G  GLPG  G  G  GE         G  G  GDPG  G  G KGE 
Sbjct: 1026 KGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEM 1085

Query: 1019 GPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP---GPIGLQGLP 1075
            G PGPPG +GP G  GA G+ G PG  G  G  G  G +G +G  GPP   GP GL G P
Sbjct: 1086 GQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFP 1145

Query: 1076 GPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSP 1135
            G  G  G  GD G  G PGP G +G  G   A     PPG  GN G  G KG+ G  G P
Sbjct: 1146 GSPGPMGIRGDQGRDGIPGPAGEKGETGLLRA-----PPGPRGNPGAQGAKGDRGAPGFP 1200

Query: 1136 GIQGEPGVKGPRGERGEKGESGQPGEPGPPGP--KGPTGDDGPKGNPGPVGFPGDPGPPG 1193
            G+ G  G  G  G RG  G  G PG PG PG    G TG+ GP G+ G  G PG PGPPG
Sbjct: 1201 GLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPG 1260

Query: 1194 EG--GPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGA 1251
                G +G  G+ G  G  G PG  G  GP G  G PG  G  GP G PG +G  G KG 
Sbjct: 1261 SHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGE 1320

Query: 1252 KGDPGAIGAPGKTGPVGPAGPAGKPGPDG---LRGLPGSVGQQGRPGATGQAGPPGPVGP 1308
            KG+PG +G+ G  GP+GP GP G  G  G   +  LPGS G  G PG  G  G PGP GP
Sbjct: 1321 KGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGP 1380

Query: 1309 PGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGP 1368
            PG  G  G  G  G+ G P   G  GP GE+G KG +G PGP GS       G+PG  G 
Sbjct: 1381 PGNLGPCGPRGKPGKDGKP---GTPGPAGEKGNKGSKGEPGPAGSD------GLPGLKGK 1431

Query: 1369 IGPGGPP 1375
             G  G P
Sbjct: 1432 RGDSGSP 1438



 Score =  804 bits (2077), Expect = 0.0
 Identities = 516/1242 (41%), Positives = 594/1242 (47%), Gaps = 217/1242 (17%)

Query: 401  GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGAR 460
            G  G  G  G PGP G PG  G  G  G  GPQGP+G  GL G  G  G RG +G  G  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 461  GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 520
            G PG PG  G+ G  GL G+PG  G +G+ G  GLPG  G  G  G  G  G +G P + 
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 521  GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQG-- 578
                L   KG PG+PG PG +G+ GP G  G +GP   PGPPG  G PG  G  GP+G  
Sbjct: 163  EDIEL-DAKGDPGLPGAPGPQGLPGPPGFPGPVGP---PGPPGFFGFPGAMGPRGPKGHM 218

Query: 579  ---AIGPHGEKGPQGKPGLPGMPGS-----DGPPGHPGKEGPPGTKGNQGPSGPQGPLGY 630
                IG  GE+G +G  G PG PG+      GP      +G  G KG  G  GP GP G 
Sbjct: 219  GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGL 278

Query: 631  PGP--------------RGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVP 676
            PG               +G  G DG+ G  G +G KG  GFPG  G+ G+KG +G++G P
Sbjct: 279  PGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPP 338

Query: 677  GSRGED---------------GPEGPKGRTGPTGDPGPPGLMGEKG--KLGVPGLPGYPG 719
            G RG                 GP GP+G  GP G  GPPG+ G  G  + G+ G PG+PG
Sbjct: 339  GFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPG 398

Query: 720  RQGPKG--------SLGFPGFPGASGEKGARGLSGKSGPRGE----RGPTGPRGQRGPRG 767
             +G KG        ++G PG PG +G  G  G  G  GP G+    +GP G  G  G  G
Sbjct: 399  LKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLG 458

Query: 768  ATGKSGAKGTSGGDG------PH--GPPGERGLPGPQGPNGFPGP------KGPPGPPGK 813
            + G  G  G  G  G      P+  GPPG  GLPG  G  G PG       KG PG PG 
Sbjct: 459  SPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGN 518

Query: 814  DGLPGHPGQRGEVGFQGKTGPPG----PPGVVGPQGAAGETGPMGERGHPGPPGPPGEQG 869
             GLPG PG  G  G  G  G  G    P G VG  G  G  G  G +G  G PG PG +G
Sbjct: 519  TGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKG 578

Query: 870  LPGT------AGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSG 923
            LPG       +G++G +G PG PG+PG  GPAG  G PG     G  G PGL+G +G  G
Sbjct: 579  LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY----GPQGEPGLQGTQGVPG 634

Query: 924  PPGPAGSPGERG-------AAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD 976
             PGP G  G RG         G  GP GPPG PGPQGPPG  G  G  G+ G  GP G  
Sbjct: 635  APGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEP 694

Query: 977  GVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGT------------------------- 1011
            G+ G +G PGP GP G  G  G KG +G PG+ G                          
Sbjct: 695  GIPG-IGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPG 753

Query: 1012 -------KGNKGEHGP---------PGPPG------PIGPVGQPGAAGADGEPG------ 1043
                   +GN GEHG          PG PG      P G  GQPG  G  G PG      
Sbjct: 754  TPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGP 813

Query: 1044 --ARGPQGHFGAKGDEGTRGFNGPPGPIGLQGL-----------PGPSGEKGETGDVGPM 1090
              A+G  G  G KG +G RG  GP G  G+ GL           PG  G +GE G +G  
Sbjct: 814  RGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQR 873

Query: 1091 GPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGER 1150
            G PG PG  GP G +G  G  G PG +G  GPPG  G PG+ GSPGI   PGVKG RG  
Sbjct: 874  GYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGI---PGVKGQRGTP 930

Query: 1151 GEKGESGQPGEPGP------------PGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPR 1198
            G KGE G  G PGP            PG KG  G+ G KGN G  G PG  G  G  GP 
Sbjct: 931  GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPA 990

Query: 1199 GQDGAKGDRGEDGEPGQPGS---PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDP 1255
            G  G +GD G  G PG+PG    PG  G  G PG  GKRG  G PG  GR G  G  G  
Sbjct: 991  GPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQ 1050

Query: 1256 GAIGAPGKTGPV--GPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG 1313
            G  G PG +     GP GP G PG  G  G  G +GQ G PG  G AGP G  G PG PG
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 1314 LRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPG---PQGSPGQKGEMGIPGASGPIG 1370
            L G  G  G+ G  G+ GL+GPPG +G  G  G PG   P G  G +G  GIPG +G  G
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170

Query: 1371 -------PGGPPGLPGPAGPK------------GAKGATGPGGPKGEKGVQGPPGHPGPP 1411
                   P GP G PG  G K            G KGA G  GP+G  G++G PG PG P
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 1412 GEVIQPLPIQMPKKT-RRSVDGSRLMQEDEAIPTGGAPGSPG 1452
            G +I       P +T  R   GSR         + GAPG PG
Sbjct: 1231 GAII-------PGQTGNRGPPGSR--------GSPGAPGPPG 1257



 Score =  744 bits (1921), Expect = 0.0
 Identities = 463/1087 (42%), Positives = 537/1087 (49%), Gaps = 113/1087 (10%)

Query: 263  PQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAG 322
            PQ     PG        S  P L  A   P GLKG KGE     PG    G PG  G AG
Sbjct: 370  PQGPSGPPGVPGS--PGSSRPGLRGAPGWP-GLKGSKGERG--RPGKDAMGTPGSPGCAG 424

Query: 323  LIGPPGIQGNPGPVGD-------PGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGG 375
              G PG  G PGP GD       PG+ G PG  G PG  G  GP G   +L  +     G
Sbjct: 425  SPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPG 484

Query: 376  DKG-PVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGS---PGLKGESGDL- 430
              G P +           +Q    L+G PG  G TG PG  G PG+   PGLKGE G+  
Sbjct: 485  PPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETL 544

Query: 431  ---GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG---VKGDRGFDGLPGLPGEK 484
               G  G  G  GL G PG+ G  G  G  G +G+PG  G   + G++G  G PG PG  
Sbjct: 545  QPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSP 604

Query: 485  GHRGDTGAQGLPG--PPGEDGERGDDGEIGPRGLPGESGPRGLLGPK----GPPGIPGPP 538
            G  G  G  G PG  P GE G +G  G  G  G PGE+GPRG L       GPPG PGPP
Sbjct: 605  GSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664

Query: 539  GVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT--------------QGLPGPQGAIGPHG 584
            G  G  GP G  GSLG  G+PG PG  G PG               QG PG +G++G  G
Sbjct: 665  GHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPG 724

Query: 585  EKGPQGKPGLPGMPGSDGPPG--HPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGI 642
            + G  G PG PG+PG+ G P    PG  G PG  G +G SG  G +G PG  G+ G  G 
Sbjct: 725  KMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGN 784

Query: 643  RGLKGHKGEKGEDGFPGFKGDIG--VKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPP 700
             GL G +G+ G+ G PG +G  G  ++G RG  G+PG  G  G +G +G+TGP GDPG P
Sbjct: 785  EGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIP 844

Query: 701  GL--MGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTG 758
            GL   G  G+ G PG+PG+ G  GP G  G+PG PG  G  G  G+ G  G  G  GP G
Sbjct: 845  GLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPG 904

Query: 759  PRGQRGP---RGATGKSGAKGTSGGDGPHGPPGERGLPGPQ------GPNGFPGPKGPPG 809
            P G  G    RG+ G  G KG  G  G  G  G++G PGP       G  G PG KG  G
Sbjct: 905  PPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAG 964

Query: 810  PPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQG 869
             PG+ G  G PG  G  G +G  GP GPPG   P+G  G TG  GE G  G PG  G  G
Sbjct: 965  NPGEKGNRGVPGMPGLKGLKGLPGPAGPPG---PRGDLGSTGNPGEPGLRGIPGSMGNMG 1021

Query: 870  LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGL--------PGTAGGPGLKGNEGP 921
            +PG+ GK GT G PG  G PG  G  GL+G  GE G         PG  G PGL G+ G 
Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGK 1081

Query: 922  SGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGP 981
             G  G  G PG  G AG  G  G PG PG  G PG  G+ G  G KG +GP G   ++GP
Sbjct: 1082 KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPG---IRGP 1138

Query: 982  VGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE-HGPPGPPGPIGPVGQPGAAGADG 1040
             GLPG  G PG  G  GD+G  G PG  G KG  G    PPGP G  G  G  G  GA G
Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG 1198

Query: 1041 EPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQG--LPGPSGEKGETGDVGPMGPPGPPGP 1098
             PG  G +G  G  G  G  G  G PGP GL G  +PG +G +G  G  G  G PGPPGP
Sbjct: 1199 FPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGP 1258

Query: 1099 --------RGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGER 1150
                    +G  G  G  GP+GPPG  G++GPPG  G PG  G PG +G+PG +G  G +
Sbjct: 1259 PGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVK 1318

Query: 1151 GEKGESG------------------------------QPGEPGPPGPKGPTGDDGPKGNP 1180
            GEKG  G                               PG PGPPG  G  G  G  G P
Sbjct: 1319 GEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPP 1378

Query: 1181 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1240
            GP G  G  GP G+ G  G+ G  G  GE G  G  G PGP G +G PG  GKRG +GSP
Sbjct: 1379 GPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438

Query: 1241 GSEGRQG 1247
             +   +G
Sbjct: 1439 ATWTTRG 1445



 Score =  617 bits (1590), Expect = e-176
 Identities = 389/933 (41%), Positives = 463/933 (49%), Gaps = 175/933 (18%)

Query: 289  AHGPRGLKGEKGEPAVLE--------PGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGD-- 338
            A G  GLKGEKGE    E        PG+   G PG +G  G+ G PG++G PGP G+  
Sbjct: 530  AQGDPGLKGEKGETLQPEGQVGVPGDPGL--RGQPGRKGLDGIPGTPGVKGLPGPKGELA 587

Query: 339  ----PGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--------GDKGPVVAAQEA 386
                 G++GPPG  G PGS G  GP G     P  +G  G        G  G      EA
Sbjct: 588  LSGEKGDQGPPGDPGSPGSPGPAGPAG-----PPGYGPQGEPGLQGTQGVPGAPGPPGEA 642

Query: 387  QAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLG--------------- 431
              +  L  +   + GPPGP G  G PGP G PG PG  G+ GD G               
Sbjct: 643  GPRGELSVST-PVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF 701

Query: 432  --PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDR-----GFDGLPGLPGEK 484
              P GP+G QG  G  G  G  G+ G  G  G PG PG KG+      G  G PG PGE+
Sbjct: 702  PGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGER 761

Query: 485  GHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGP-----KGPPGIPGPPG 539
            G+ G+ G  GLPG PG  G  G++G  GPRG PG+ GP G  GP     +GP G  G PG
Sbjct: 762  GNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPG 821

Query: 540  VRGMDGPQGPKGSLGPQGEPGPPGQQ-----GTPGTQGLPGPQGAIGPHGEKGPQGKPGL 594
            + G+ G QG +G  GP+G+PG PG       G  G+ G+PG QG +GP G++G  G PG+
Sbjct: 822  LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGI 881

Query: 595  PGMPGSDGP---PGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKG- 650
             G PG DG     G PG  GPPG  GN G  G +G  G PG +G +G  G +G +G KG 
Sbjct: 882  LGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGN 941

Query: 651  -----------EKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP 699
                       +KGE G  GF G+ G KG+RG  G+PG +G  G  GP G  GP GD G 
Sbjct: 942  PGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS 1001

Query: 700  PGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGP 759
             G  GE G  G+PG  G  G  G KG  G  GFPG +G  G  G+ G  G +GE G +  
Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYS-- 1059

Query: 760  RGQR-GPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPG 818
             G R GP G TG  G  G  G        GE G PGP G  G  GP+G PG PG  GLPG
Sbjct: 1060 EGTRPGPPGPTGDPGLPGDMG------KKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPG 1113

Query: 819  HPGQRGEVGFQGKTGPPGPPGVVGPQGAAG---ETGPMGERGH------PGPPG------ 863
             PG  G++GF+G  G  GPPG+ GP G  G     GPMG RG       PGP G      
Sbjct: 1114 KPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETG 1173

Query: 864  ----PPGEQGLPGTAGKEGTKGDPGPPGAPGKDG---------PAGLRGFPGERGLPGTA 910
                PPG +G PG  G +G +G PG PG PG+ G         P G+ GFPG  GLPG  
Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233

Query: 911  --------GGPGLKGNEGPSGPPGPAGS--------------PGERGAAGSGGPIGPPGR 948
                    G PG +G+ G  GPPGP GS              PG +G  G+ G +GPPGR
Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293

Query: 949  ---------PGPQGPPGAAGEKGVPGEKG------------PIGPTGRDGVQGPVG---- 983
                     PGP+G PG  G  GV GEKG            PIGP G  GV+G  G    
Sbjct: 1294 LGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKI 1353

Query: 984  --LPGPAGPPGVAGEDGDKGEVGDPGQKGT------KGNKGEHGPPGPPGPIGPVG---- 1031
              LPG  GPPG  GE G +GE G PG  G       +G  G+ G PG PGP G  G    
Sbjct: 1354 ISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGS 1413

Query: 1032 --QPGAAGADGEPGARGPQGHFGAKGDEGTRGF 1062
              +PG AG+DG PG +G +G  G+     TRGF
Sbjct: 1414 KGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGF 1446



 Score =  368 bits (945), Expect = e-101
 Identities = 255/627 (40%), Positives = 279/627 (44%), Gaps = 122/627 (19%)

Query: 936  AAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP---PG 992
            AA  G      G+    G  G  GEKG P   GP G  G+ G  GP GLPGP GP   PG
Sbjct: 26   AASKGCVCKDKGQCFCDGAKGEKGEKGFP---GPPGSPGQKGFTGPEGLPGPQGPKGFPG 82

Query: 993  VAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGE---PGARGPQG 1049
            + G  G KG  G  G  G  G+ G  G PG  GP G VG PG +G+ GE   PG  G  G
Sbjct: 83   LPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLG 142

Query: 1050 HFGAKGDEGTRGFNGPP-----------GPIGLQGLPGPSGEKGETGDVGPMGPPGPP-- 1096
            + G  G  G +G  G P           G  GL G PGP G  G  G  GP+GPPGPP  
Sbjct: 143  YPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGF 202

Query: 1097 -------GPRGP--------------AGPNGADGPQGPPGGV------------------ 1117
                   GPRGP               G  G  GP GPPG V                  
Sbjct: 203  FGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKG 262

Query: 1118 -----GNLGPPGEKGEPGES--------GSPGIQGEP---GVKGPRGERGEKGESGQPGE 1161
                 G  GPPG  G PGES        G PG+QG+P   GV G  G  G KG  G PG 
Sbjct: 263  DKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGL 322

Query: 1162 PGPPGPKGPTGDDGPKGNPGPVGF------PGDPGPPGEGGPRGQDGAKGDRGEDGEPGQ 1215
             G  G KG  GD GP G  GP  +       GD G PG  GPRG  G +G  G  G PG 
Sbjct: 323  MGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGS 382

Query: 1216 PGS--PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA 1273
            PGS  PG  G  G PG  G +G  G PG +      G  G PG  G+PG  G  GP GP 
Sbjct: 383  PGSSRPGLRGAPGWPGLKGSKGERGRPGKD----AMGTPGSPGCAGSPGLPGSPGPPGPP 438

Query: 1274 G----KPGPDGLRGLPGSVGQQGRPGATGQAGP-----------PGPVGPPGLPGLRGDA 1318
            G    + GP G  GLPG +G  G PG  G  G            PGP G PGLPGL G  
Sbjct: 439  GDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVK 498

Query: 1319 GAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGE----------MGIPGASGP 1368
            G  G +G  GL G  G PG  G  G  G PG QG PG KGE          +G+PG  G 
Sbjct: 499  GIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGL 558

Query: 1369 IGPGGPPGLPGPAGPKGAKGATGPGGP---KGEKGVQGPPGHPGPPGEVIQPLPIQMPKK 1425
             G  G  GL G  G  G KG  GP G     GEKG QGPPG PG PG    P P      
Sbjct: 559  RGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPG---SPGPAGPAGP 615

Query: 1426 TRRSVDGSRLMQEDEAIPTGGAPGSPG 1452
                  G   +Q  + +P  GAPG PG
Sbjct: 616  PGYGPQGEPGLQGTQGVP--GAPGPPG 640



 Score =  354 bits (908), Expect = 4e-97
 Identities = 222/544 (40%), Positives = 270/544 (49%), Gaps = 57/544 (10%)

Query: 259  QNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGML-VEGPPGP 317
            + ++    +P P E   ++     P L+  A  P G KG +G P +  PG+  ++G PGP
Sbjct: 933  KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP-GEKGNRGVPGM--PGLKGLKGLPGP 989

Query: 318  EGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--- 374
             GP G  G  G  GNPG   +PG RG PG  G  G  G+ G  GT L  P R G  G   
Sbjct: 990  AGPPGPRGDLGSTGNPG---EPGLRGIPGSMGNMGMPGSKGKRGT-LGFPGRAGRPGLPG 1045

Query: 375  -----GDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGD 429
                 GDKG    ++  +             GPPGP G  G PG +G+ G  G  G  G 
Sbjct: 1046 IHGLQGDKGEPGYSEGTRP------------GPPGPTGDPGLPGDMGKKGEMGQPGPPGH 1093

Query: 430  LGPQGPRGPQGLTGPPG---KAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGH 486
            LGP GP G  G  G PG   K G  G  G  G +G+ G PG++G  G  G PG PG  G 
Sbjct: 1094 LGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGI 1153

Query: 487  RGDTGAQGLPGPPGEDGERGD-DGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDG 545
            RGD G  G+PGP GE GE G      GPRG PG  G +G    +G PG PG PG +G  G
Sbjct: 1154 RGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKG---DRGAPGFPGLPGRKGAMG 1210

Query: 546  PQGPKGSLGPQGEPGPPGQQGT--PGTQGLPGPQGAIGPHGEKGPQGKPG--LPGMPGSD 601
              GP+G  G +G PGPPG  G   PG  G  GP G+ G  G  GP G PG  + G+ G  
Sbjct: 1211 DAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDK 1270

Query: 602  GPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF- 660
            G  GHPG +GPPGT G+ GP G  G  G PG  G +G  G +G  G KGEKG  GF G  
Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSI 1330

Query: 661  --------KGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVP 712
                    KG  GV+GD G + +    G  GP G  G  G  G+PGPPG  G  G  G  
Sbjct: 1331 GPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPR 1390

Query: 713  GLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKS 772
            G PG  G+         PG PG +GEKG +G  G+ GP G  G  G +G+RG  G+    
Sbjct: 1391 GKPGKDGK---------PGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATW 1441

Query: 773  GAKG 776
              +G
Sbjct: 1442 TTRG 1445



 Score =  157 bits (396), Expect = 1e-37
 Identities = 109/293 (37%), Positives = 137/293 (46%), Gaps = 32/293 (10%)

Query: 264  QSQDPTPGEEEEILESSLL--PPLEEAAHGPRGLKGEKGEPAVLEPGML----VEGPPGP 317
            Q +D  PG   E  E+ LL  PP      G +G KG++G P    PG+       G  GP
Sbjct: 1157 QGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGF--PGLPGRKGAMGDAGP 1214

Query: 318  EGPAGLIGPPGIQGNPGPV--GDPGERGPPGRAGLPGSDGAPGPPGTSLM-LPFRFGSGG 374
             GP G+ G PG  G PG +  G  G RGPPG  G PG+ G PGPPG+ ++ +    GS G
Sbjct: 1215 RGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMG 1274

Query: 375  --GDKGPVVAAQEAQAQAIL-QQARLALRGP------------------PGPMGYTGRPG 413
              G KGP   A +      L       L GP                  PG +G  G PG
Sbjct: 1275 HPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPG 1334

Query: 414  PLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRG 473
            P+G  G PG++G+ G L      G  G  G PG+ G +G  G  G  G  G  G +G  G
Sbjct: 1335 PIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPG 1394

Query: 474  FDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLL 526
             DG PG PG  G +G+ G++G PGP G DG  G  G+ G  G P     RG +
Sbjct: 1395 KDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGFV 1447


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1637

 Score =  894 bits (2311), Expect = 0.0
 Identities = 580/1363 (42%), Positives = 670/1363 (49%), Gaps = 260/1363 (19%)

Query: 291  GPRGLKGEKGEPAVL-EPGML----VEGPPGPEGPAG---------------LIGPPGIQ 330
            G +G KGEKG P     PG       EG PGP+GP G               + G PG  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 331  GNPGPVGDPGERGPPGRAGLPGSDGA------PGPPGTSLMLPFRFGSGG--GDKGPVVA 382
            G+PG  G PG  GP G  G+PG  G+      PG PGT L  P   G+ G  G KG    
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGT-LGYPGIPGAAGLKGQKGAPAK 161

Query: 383  AQEAQAQAILQQARLALRGPPGPMGYTGRPG---PLGQPGSPGLKGESGDLGPQGP---- 435
             ++ +  A   +    L G PGP G  G PG   P+G PG PG  G  G +GP+GP    
Sbjct: 162  EEDIELDA---KGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHM 218

Query: 436  ----------RGPQGLTGPPGKAGR--------------RGRAGADGA------------ 459
                      RG +GLTGPPG  G               +G  G  GA            
Sbjct: 219  GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGL 278

Query: 460  --------RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI 511
                    +G PGDPG++G  G DG+PG PG +G +G+   +G PG  GEDG +G  G+I
Sbjct: 279  PGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN---RGFPGLMGEDGIKGQKGDI 335

Query: 512  GP------------------RGLPGESGPRGLLGPKGP---PGIPGPPG-----VRGMDG 545
            GP                   G PG  GPRG  GP+GP   PG+PG PG     +RG  G
Sbjct: 336  GPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPG 395

Query: 546  PQGPKGSLGPQGEPGP-----PGQQGTPGTQGLPGPQGAIGPHGE----KGPQGKPGLPG 596
              G KGS G +G PG      PG  G  G+ GLPG  G  GP G+    KGP G  GLPG
Sbjct: 396  WPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPG 455

Query: 597  MPGSDGPPGHPGKEGPPGTKGNQGP--SGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGE 654
              GS G PG  G +G PG    Q P   GP G  G PG  GVKG+ G +G  G KG  G 
Sbjct: 456  YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515

Query: 655  DG---------FPGFKGDIGVKGDRGE-------VGVPGSRGEDGPEGPKGRTGPTGDPG 698
             G         FPG +GD G+KG++GE       VGVPG  G  G  G KG  G  G PG
Sbjct: 516  PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575

Query: 699  PPGLMGEKGKL------------GVPGLPGYPGRQGPKGSLGF-----PGFPGASGEKGA 741
              GL G KG+L            G PG PG PG  GP G  G+     PG  G  G  GA
Sbjct: 576  VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635

Query: 742  RGLSGKSGPRGER----------GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG 791
             G  G++GPRGE           GP GP G  GP+G  G  G+ G  G  G  GP GE G
Sbjct: 636  PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPG 695

Query: 792  LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP--------PGVVGP 843
            +PG   P G PGPKG  G PG  G  G PG+ GE G  GK G PG         PG  G 
Sbjct: 696  IPGIGFP-GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGT 754

Query: 844  QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE 903
             G  GE G  GE G  G PG PG  G PG  G +G +GDPG PG PG+ GP G R   G 
Sbjct: 755  PGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPG-RCIEGP 813

Query: 904  RGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSG--GPIGPPGRPGPQGPPGAAGEK 961
            RG  G  G  GLKG +G  G  GP G PG  G   SG  G  G PG PG QG  G  G++
Sbjct: 814  RGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQR 873

Query: 962  GVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPG------QKGTKGNK 1015
            G PG  G +GP G DGV G +G PG  GPPG  G  G  G+ G PG      Q+GT G K
Sbjct: 874  GYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAK 933

Query: 1016 GEHGPPGPPGP------IGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPI 1069
            GE G  G PGP      IG  G+PG  G  G PG            ++G RG  G PG  
Sbjct: 934  GEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPG------------EKGNRGVPGMPGLK 981

Query: 1070 GLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP 1129
            GL+GLPGP+G  G  GD+G  G PG PG RG  G  G  G  G  G  G LG PG  G P
Sbjct: 982  GLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRP 1041

Query: 1130 GESGSPGIQGE-----------PGVKGPRGERG---EKGESGQPGEPGPPGPKGPTGDDG 1175
            G  G  G+QG+           PG  GP G+ G   + G+ G+ G+PGPPG  GP G +G
Sbjct: 1042 GLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101

Query: 1176 PKGNPGPVGFPGDPGPPGEGGPRGQDGAKGD---RGEDGEPGQPGSPGPTG------ENG 1226
              G+PG  G PG PGP G+ G +G  G  G    RG  G PG PGSPGP G       +G
Sbjct: 1102 APGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDG 1161

Query: 1227 PPGPLGKRGPAG----SPGSEGRQGGKGAKGD---------PGAIGAPGKTGPVGPAGPA 1273
             PGP G++G  G     PG  G  G +GAKGD         PG  GA G  GP GP G  
Sbjct: 1162 IPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIE 1221

Query: 1274 GKPGPDGLRG--LPGSVGQQGRPGATGQAGPPGPVGPPG--LPGLRGDAGAKGE---KGH 1326
            G PGP GL G  +PG  G +G PG+ G  G PGP GPPG  + G++GD G+ G    KG 
Sbjct: 1222 GFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP 1281

Query: 1327 PGLIGLIGPPGEQGEKGDRGLPGP------QGSPGQKGEMGIPGASGPIGPGGPPGLPGP 1380
            PG  G +GPPG  G  G  GLPGP      QG PG KGE G PG  G IGP GP G  GP
Sbjct: 1282 PGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGP 1341

Query: 1381 AGPKG---------AKGATGPGGPKGEKGVQGPPGHPGPPGEV 1414
             G +G           G+ GP G  GE G+QG PG PGPPG +
Sbjct: 1342 PGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNL 1384



 Score =  877 bits (2267), Expect = 0.0
 Identities = 556/1317 (42%), Positives = 647/1317 (49%), Gaps = 201/1317 (15%)

Query: 264  QSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGL 323
            + Q   P +EE+I   +   P    A GP+GL G  G P          GP GP GP G 
Sbjct: 153  KGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFP----------GPVGPPGPPGF 202

Query: 324  IGPPGIQGNPGPVGDPGER--GPPGRAGLPGSDGAPGPPGTSLML----PFRFGSGG--G 375
             G PG  G  GP G  GER  G  G  G+ G  G PGPPGT ++       R    G  G
Sbjct: 203  FGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKG 262

Query: 376  DKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPG------------- 422
            DKG +          +  ++  + +G PG  G  G+PG  G PG PG             
Sbjct: 263  DKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGL 322

Query: 423  -----LKGESGDLGPQGPRGP------------QGLTGPPGKAGRRGRAGADGARGMPGD 465
                 +KG+ GD+GP G RGP            +G  GPPG  G RG  G  G  G+PG 
Sbjct: 323  MGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGS 382

Query: 466  PGVK--GDRGFDGLPGLPGEKGHRGD--------------TGAQGLPGPPGEDGERGD-- 507
            PG    G RG  G PGL G KG RG                G+ GLPG PG  G  GD  
Sbjct: 383  PGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIV 442

Query: 508  -----------DGEIGPRGLPGESGPRGLLGP--------KGPPGIPGPPGVRGMDGPQG 548
                        G +G  G+PG  GP+G  G          GPPG+PG PG+ G+ G  G
Sbjct: 443  FRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPG 502

Query: 549  PKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKG----PQGKPGLPGMPGSDGPP 604
             +G+ G +G PG PG  G PG  G PG QG  G  GEKG    P+G+ G+PG PG  G P
Sbjct: 503  RQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQP 562

Query: 605  GHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF--KG 662
            G  G +G PGT G +G  GP+G L   G +G +G  G  G  G  G  G  G PG+  +G
Sbjct: 563  GRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQG 622

Query: 663  DIGVKGDRGEVGVPGSRGEDGPEG----------PKGRTGPTGDPGP---PGLMGEKGKL 709
            + G++G +G  G PG  GE GP G          P G  GP G PGP   PG+ G  GK 
Sbjct: 623  EPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKC 682

Query: 710  GVPGLPG-----------YPGRQGPKGSLGFPGFPGA---SGEKGARGLSGKSGPRGERG 755
            G PGLPG           +PG  GPKG  GFPG  G+    G+ G  GL GK G  G +G
Sbjct: 683  GDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKG 742

Query: 756  ------PTGPR--GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP 807
                  P GP   G  G RG +G+ G  G  G  G  G PG  GL GP+G  G PGP G 
Sbjct: 743  EPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGE 802

Query: 808  PGPPGK--------DGLPGHPGQRGEVGFQGKTGPPGPPGVVG--PQGAAGETGPMGERG 857
             GPPG+         GLPG  G +G+ G +GKTGP G PG+ G    G  GETG  G  G
Sbjct: 803  QGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPG 862

Query: 858  HPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKG 917
            H G  GP G++G PG         +PG  G PG+DG  G+ GFPG  G PG  G PG  G
Sbjct: 863  HQGEMGPLGQRGYPG---------NPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPG 913

Query: 918  NEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP------GPQGPPGAAGEKGVPGEKGPIG 971
              G  G PG  G  G  GA G  G  G PG        G +G PG  G  G PGEKG  G
Sbjct: 914  QRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRG 973

Query: 972  PTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVG 1031
              G  G++G  GLPGPAGPPG  G+ G  G  G+PG +G  G+ G  G PG  G  G +G
Sbjct: 974  VPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLG 1033

Query: 1032 QPGAAGADGEPGARGPQGHFGAKG-DEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPM 1090
             PG AG  G PG  G QG  G  G  EGTR   GPPGP G  GLPG  G+KGE      M
Sbjct: 1034 FPGRAGRPGLPGIHGLQGDKGEPGYSEGTRP--GPPGPTGDPGLPGDMGKKGE------M 1085

Query: 1091 GPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKG---------EPGESGSPGIQGEP 1141
            G PGPPG  GPAGP GA G  G PG  G  GP G+ G          PG  G PG+ G P
Sbjct: 1086 GQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFP 1145

Query: 1142 GVKGPRGERGEKGESGQPGEPG----------PPGPKGPTGDDGPKGNPGPVGFPGDPGP 1191
            G  GP G RG++G  G PG  G          PPGP+G  G  G KG+ G  GFPG PG 
Sbjct: 1146 GSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGR 1205

Query: 1192 PGEGGPRGQDGAKGDRGEDGEPGQPGS--PGPTGENGPPGPLGKRG---PAGSPGSE--G 1244
             G  G  G  G  G  G  G PG PG+  PG TG  GPPG  G  G   P G PGS   G
Sbjct: 1206 KGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIG 1265

Query: 1245 RQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL---------RGLPGSVGQQGRPG 1295
             +G KG+ G PG  G PG  G +GP G  G PG  GL         +G PG  G++G PG
Sbjct: 1266 IKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG 1325

Query: 1296 ATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPG 1355
              G  GPPGP+GP G PG+RGD G       PG  G  G PGE G +G+ G PGP G+ G
Sbjct: 1326 FLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLG 1385

Query: 1356 QKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1412
              G  G PG        G PG PGPAG KG KG+ G  GP G  G+ G  G  G  G
Sbjct: 1386 PCGPRGKPGKD------GKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSG 1436



 Score =  831 bits (2146), Expect = 0.0
 Identities = 509/1147 (44%), Positives = 580/1147 (50%), Gaps = 97/1147 (8%)

Query: 291  GPRGLKGEKGEPAVLEPGMLVE-----------GPPGPEG---PAGLIGPPGIQGNPGPV 336
            G +G KG+ G P    P    +           GPPGP G   P G  GPPG+ G+PG  
Sbjct: 327  GIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGS- 385

Query: 337  GDPGERGPPGRAGLPGSDGAPGPPGTSLM-LPFRFGSGGGDKGPVVAAQEAQAQAILQQA 395
              PG RG PG  GL GS G  G PG   M  P   G  G    P           I+ + 
Sbjct: 386  SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFR- 444

Query: 396  RLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPR--GPQGLTGPPGKAGRRGR 453
                +GPPG  G  G  G  G PG  G KGE G L  Q P   GP GL G PG  G +G 
Sbjct: 445  ----KGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGI 500

Query: 454  AGADGARGMPGDPGVKGDRGFDGLPGLPGE------KGHRGDT-GAQGLPGPPGEDGERG 506
             G  GA G+ G PG  G+ G  G PG PG       KG +G+T   +G  G PG+ G RG
Sbjct: 501  PGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRG 560

Query: 507  DDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQ-- 564
              G  G  G+PG  G +GL GPKG   + G  G +G  G  G  GS GP G  GPPG   
Sbjct: 561  QPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGP 620

Query: 565  QGTPGTQGLPGPQGAIGPHGEKGPQGKPGL----PGMPGSDGPPGHPGKEGPPGTKGNQG 620
            QG PG QG  G  GA GP GE GP+G+  +    PG PG  GPPGHPG +GPPG  G+ G
Sbjct: 621  QGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLG 680

Query: 621  PSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRG 680
              G  G    PGP G  G+ GI G  G  G KG+ GFPG KG +G  G  GE G+PG  G
Sbjct: 681  KCGDPG---LPGPDGEPGIPGI-GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPG 736

Query: 681  EDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKG 740
              G +G      P G PG PG  GE+G  G  G  G PG  G       PG PG  G  G
Sbjct: 737  LPGAKGEPAVAMP-GGPGTPGFPGERGNSGEHGEIGLPGLPG------LPGTPGNEGLDG 789

Query: 741  ARGLSGKSGPRGERGPTGP--RGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGP 798
             RG  G+ GP GE+GP G    G RG +G  G +G KG  G  G  GP G+ G+PG    
Sbjct: 790  PRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDR- 848

Query: 799  NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP---------PGVVGPQGAAGE 849
            +GFPG  G PG PG  G  G  GQRG  G  G  GPPG          PG +GP G  G 
Sbjct: 849  SGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGN 908

Query: 850  TGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP---GKDGPAGLRGFPGERGL 906
             G  G+RG PG PG  G++G PG  G++G KG+PGP       G  G  GL+GF G  G 
Sbjct: 909  PGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGE 968

Query: 907  PGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGE 966
             G  G PG+ G +G  G PGPAG PG RG  GS    G PG PG +G PG+ G  G+PG 
Sbjct: 969  KGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS---TGNPGEPGLRGIPGSMGNMGMPGS 1025

Query: 967  KGPIGPTGRDGVQGPVGLPGPAGPPGVAGE--------DGDKGEVGDPGQKGTKGNKGEH 1018
            KG  G  G  G  G  GLPG  G  G  GE         G  G  GDPG  G  G KGE 
Sbjct: 1026 KGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEM 1085

Query: 1019 GPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP---GPIGLQGLP 1075
            G PGPPG +GP G  GA G+ G PG  G  G  G  G +G +G  GPP   GP GL G P
Sbjct: 1086 GQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFP 1145

Query: 1076 GPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSP 1135
            G  G  G  GD G  G PGP G +G  G   A     PPG  GN G  G KG+ G  G P
Sbjct: 1146 GSPGPMGIRGDQGRDGIPGPAGEKGETGLLRA-----PPGPRGNPGAQGAKGDRGAPGFP 1200

Query: 1136 GIQGEPGVKGPRGERGEKGESGQPGEPGPPGP--KGPTGDDGPKGNPGPVGFPGDPGPPG 1193
            G+ G  G  G  G RG  G  G PG PG PG    G TG+ GP G+ G  G PG PGPPG
Sbjct: 1201 GLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPG 1260

Query: 1194 EG--GPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGA 1251
                G +G  G+ G  G  G PG  G  GP G  G PG  G  GP G PG +G  G KG 
Sbjct: 1261 SHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGE 1320

Query: 1252 KGDPGAIGAPGKTGPVGPAGPAGKPGPDG---LRGLPGSVGQQGRPGATGQAGPPGPVGP 1308
            KG+PG +G+ G  GP+GP GP G  G  G   +  LPGS G  G PG  G  G PGP GP
Sbjct: 1321 KGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGP 1380

Query: 1309 PGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGP 1368
            PG  G  G  G  G+ G P   G  GP GE+G KG +G PGP GS       G+PG  G 
Sbjct: 1381 PGNLGPCGPRGKPGKDGKP---GTPGPAGEKGNKGSKGEPGPAGSD------GLPGLKGK 1431

Query: 1369 IGPGGPP 1375
             G  G P
Sbjct: 1432 RGDSGSP 1438



 Score =  804 bits (2077), Expect = 0.0
 Identities = 516/1242 (41%), Positives = 594/1242 (47%), Gaps = 217/1242 (17%)

Query: 401  GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGAR 460
            G  G  G  G PGP G PG  G  G  G  GPQGP+G  GL G  G  G RG +G  G  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 461  GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 520
            G PG PG  G+ G  GL G+PG  G +G+ G  GLPG  G  G  G  G  G +G P + 
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 521  GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQG-- 578
                L   KG PG+PG PG +G+ GP G  G +GP   PGPPG  G PG  G  GP+G  
Sbjct: 163  EDIEL-DAKGDPGLPGAPGPQGLPGPPGFPGPVGP---PGPPGFFGFPGAMGPRGPKGHM 218

Query: 579  ---AIGPHGEKGPQGKPGLPGMPGS-----DGPPGHPGKEGPPGTKGNQGPSGPQGPLGY 630
                IG  GE+G +G  G PG PG+      GP      +G  G KG  G  GP GP G 
Sbjct: 219  GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGL 278

Query: 631  PGP--------------RGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVP 676
            PG               +G  G DG+ G  G +G KG  GFPG  G+ G+KG +G++G P
Sbjct: 279  PGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPP 338

Query: 677  GSRGED---------------GPEGPKGRTGPTGDPGPPGLMGEKG--KLGVPGLPGYPG 719
            G RG                 GP GP+G  GP G  GPPG+ G  G  + G+ G PG+PG
Sbjct: 339  GFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPG 398

Query: 720  RQGPKG--------SLGFPGFPGASGEKGARGLSGKSGPRGE----RGPTGPRGQRGPRG 767
             +G KG        ++G PG PG +G  G  G  G  GP G+    +GP G  G  G  G
Sbjct: 399  LKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLG 458

Query: 768  ATGKSGAKGTSGGDG------PH--GPPGERGLPGPQGPNGFPGP------KGPPGPPGK 813
            + G  G  G  G  G      P+  GPPG  GLPG  G  G PG       KG PG PG 
Sbjct: 459  SPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGN 518

Query: 814  DGLPGHPGQRGEVGFQGKTGPPG----PPGVVGPQGAAGETGPMGERGHPGPPGPPGEQG 869
             GLPG PG  G  G  G  G  G    P G VG  G  G  G  G +G  G PG PG +G
Sbjct: 519  TGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKG 578

Query: 870  LPGT------AGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSG 923
            LPG       +G++G +G PG PG+PG  GPAG  G PG     G  G PGL+G +G  G
Sbjct: 579  LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY----GPQGEPGLQGTQGVPG 634

Query: 924  PPGPAGSPGERG-------AAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD 976
             PGP G  G RG         G  GP GPPG PGPQGPPG  G  G  G+ G  GP G  
Sbjct: 635  APGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEP 694

Query: 977  GVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGT------------------------- 1011
            G+ G +G PGP GP G  G  G KG +G PG+ G                          
Sbjct: 695  GIPG-IGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPG 753

Query: 1012 -------KGNKGEHGP---------PGPPG------PIGPVGQPGAAGADGEPG------ 1043
                   +GN GEHG          PG PG      P G  GQPG  G  G PG      
Sbjct: 754  TPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGP 813

Query: 1044 --ARGPQGHFGAKGDEGTRGFNGPPGPIGLQGL-----------PGPSGEKGETGDVGPM 1090
              A+G  G  G KG +G RG  GP G  G+ GL           PG  G +GE G +G  
Sbjct: 814  RGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQR 873

Query: 1091 GPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGER 1150
            G PG PG  GP G +G  G  G PG +G  GPPG  G PG+ GSPGI   PGVKG RG  
Sbjct: 874  GYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGI---PGVKGQRGTP 930

Query: 1151 GEKGESGQPGEPGP------------PGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPR 1198
            G KGE G  G PGP            PG KG  G+ G KGN G  G PG  G  G  GP 
Sbjct: 931  GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPA 990

Query: 1199 GQDGAKGDRGEDGEPGQPGS---PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDP 1255
            G  G +GD G  G PG+PG    PG  G  G PG  GKRG  G PG  GR G  G  G  
Sbjct: 991  GPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQ 1050

Query: 1256 GAIGAPGKTGPV--GPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG 1313
            G  G PG +     GP GP G PG  G  G  G +GQ G PG  G AGP G  G PG PG
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 1314 LRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPG---PQGSPGQKGEMGIPGASGPIG 1370
            L G  G  G+ G  G+ GL+GPPG +G  G  G PG   P G  G +G  GIPG +G  G
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170

Query: 1371 -------PGGPPGLPGPAGPK------------GAKGATGPGGPKGEKGVQGPPGHPGPP 1411
                   P GP G PG  G K            G KGA G  GP+G  G++G PG PG P
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 1412 GEVIQPLPIQMPKKT-RRSVDGSRLMQEDEAIPTGGAPGSPG 1452
            G +I       P +T  R   GSR         + GAPG PG
Sbjct: 1231 GAII-------PGQTGNRGPPGSR--------GSPGAPGPPG 1257



 Score =  744 bits (1921), Expect = 0.0
 Identities = 463/1087 (42%), Positives = 537/1087 (49%), Gaps = 113/1087 (10%)

Query: 263  PQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAG 322
            PQ     PG        S  P L  A   P GLKG KGE     PG    G PG  G AG
Sbjct: 370  PQGPSGPPGVPGS--PGSSRPGLRGAPGWP-GLKGSKGERG--RPGKDAMGTPGSPGCAG 424

Query: 323  LIGPPGIQGNPGPVGD-------PGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGG 375
              G PG  G PGP GD       PG+ G PG  G PG  G  GP G   +L  +     G
Sbjct: 425  SPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPG 484

Query: 376  DKG-PVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGS---PGLKGESGDL- 430
              G P +           +Q    L+G PG  G TG PG  G PG+   PGLKGE G+  
Sbjct: 485  PPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETL 544

Query: 431  ---GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG---VKGDRGFDGLPGLPGEK 484
               G  G  G  GL G PG+ G  G  G  G +G+PG  G   + G++G  G PG PG  
Sbjct: 545  QPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSP 604

Query: 485  GHRGDTGAQGLPG--PPGEDGERGDDGEIGPRGLPGESGPRGLLGPK----GPPGIPGPP 538
            G  G  G  G PG  P GE G +G  G  G  G PGE+GPRG L       GPPG PGPP
Sbjct: 605  GSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664

Query: 539  GVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT--------------QGLPGPQGAIGPHG 584
            G  G  GP G  GSLG  G+PG PG  G PG               QG PG +G++G  G
Sbjct: 665  GHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPG 724

Query: 585  EKGPQGKPGLPGMPGSDGPPG--HPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGI 642
            + G  G PG PG+PG+ G P    PG  G PG  G +G SG  G +G PG  G+ G  G 
Sbjct: 725  KMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGN 784

Query: 643  RGLKGHKGEKGEDGFPGFKGDIG--VKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPP 700
             GL G +G+ G+ G PG +G  G  ++G RG  G+PG  G  G +G +G+TGP GDPG P
Sbjct: 785  EGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIP 844

Query: 701  GL--MGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTG 758
            GL   G  G+ G PG+PG+ G  GP G  G+PG PG  G  G  G+ G  G  G  GP G
Sbjct: 845  GLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPG 904

Query: 759  PRGQRGP---RGATGKSGAKGTSGGDGPHGPPGERGLPGPQ------GPNGFPGPKGPPG 809
            P G  G    RG+ G  G KG  G  G  G  G++G PGP       G  G PG KG  G
Sbjct: 905  PPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAG 964

Query: 810  PPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQG 869
             PG+ G  G PG  G  G +G  GP GPPG   P+G  G TG  GE G  G PG  G  G
Sbjct: 965  NPGEKGNRGVPGMPGLKGLKGLPGPAGPPG---PRGDLGSTGNPGEPGLRGIPGSMGNMG 1021

Query: 870  LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGL--------PGTAGGPGLKGNEGP 921
            +PG+ GK GT G PG  G PG  G  GL+G  GE G         PG  G PGL G+ G 
Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGK 1081

Query: 922  SGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGP 981
             G  G  G PG  G AG  G  G PG PG  G PG  G+ G  G KG +GP G   ++GP
Sbjct: 1082 KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPG---IRGP 1138

Query: 982  VGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE-HGPPGPPGPIGPVGQPGAAGADG 1040
             GLPG  G PG  G  GD+G  G PG  G KG  G    PPGP G  G  G  G  GA G
Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG 1198

Query: 1041 EPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQG--LPGPSGEKGETGDVGPMGPPGPPGP 1098
             PG  G +G  G  G  G  G  G PGP GL G  +PG +G +G  G  G  G PGPPGP
Sbjct: 1199 FPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGP 1258

Query: 1099 --------RGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGER 1150
                    +G  G  G  GP+GPPG  G++GPPG  G PG  G PG +G+PG +G  G +
Sbjct: 1259 PGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVK 1318

Query: 1151 GEKGESG------------------------------QPGEPGPPGPKGPTGDDGPKGNP 1180
            GEKG  G                               PG PGPPG  G  G  G  G P
Sbjct: 1319 GEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPP 1378

Query: 1181 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1240
            GP G  G  GP G+ G  G+ G  G  GE G  G  G PGP G +G PG  GKRG +GSP
Sbjct: 1379 GPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438

Query: 1241 GSEGRQG 1247
             +   +G
Sbjct: 1439 ATWTTRG 1445



 Score =  617 bits (1590), Expect = e-176
 Identities = 389/933 (41%), Positives = 463/933 (49%), Gaps = 175/933 (18%)

Query: 289  AHGPRGLKGEKGEPAVLE--------PGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGD-- 338
            A G  GLKGEKGE    E        PG+   G PG +G  G+ G PG++G PGP G+  
Sbjct: 530  AQGDPGLKGEKGETLQPEGQVGVPGDPGL--RGQPGRKGLDGIPGTPGVKGLPGPKGELA 587

Query: 339  ----PGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--------GDKGPVVAAQEA 386
                 G++GPPG  G PGS G  GP G     P  +G  G        G  G      EA
Sbjct: 588  LSGEKGDQGPPGDPGSPGSPGPAGPAG-----PPGYGPQGEPGLQGTQGVPGAPGPPGEA 642

Query: 387  QAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLG--------------- 431
              +  L  +   + GPPGP G  G PGP G PG PG  G+ GD G               
Sbjct: 643  GPRGELSVST-PVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF 701

Query: 432  --PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDR-----GFDGLPGLPGEK 484
              P GP+G QG  G  G  G  G+ G  G  G PG PG KG+      G  G PG PGE+
Sbjct: 702  PGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGER 761

Query: 485  GHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGP-----KGPPGIPGPPG 539
            G+ G+ G  GLPG PG  G  G++G  GPRG PG+ GP G  GP     +GP G  G PG
Sbjct: 762  GNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPG 821

Query: 540  VRGMDGPQGPKGSLGPQGEPGPPGQQ-----GTPGTQGLPGPQGAIGPHGEKGPQGKPGL 594
            + G+ G QG +G  GP+G+PG PG       G  G+ G+PG QG +GP G++G  G PG+
Sbjct: 822  LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGI 881

Query: 595  PGMPGSDGP---PGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKG- 650
             G PG DG     G PG  GPPG  GN G  G +G  G PG +G +G  G +G +G KG 
Sbjct: 882  LGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGN 941

Query: 651  -----------EKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP 699
                       +KGE G  GF G+ G KG+RG  G+PG +G  G  GP G  GP GD G 
Sbjct: 942  PGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS 1001

Query: 700  PGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGP 759
             G  GE G  G+PG  G  G  G KG  G  GFPG +G  G  G+ G  G +GE G +  
Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYS-- 1059

Query: 760  RGQR-GPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPG 818
             G R GP G TG  G  G  G        GE G PGP G  G  GP+G PG PG  GLPG
Sbjct: 1060 EGTRPGPPGPTGDPGLPGDMG------KKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPG 1113

Query: 819  HPGQRGEVGFQGKTGPPGPPGVVGPQGAAG---ETGPMGERGH------PGPPG------ 863
             PG  G++GF+G  G  GPPG+ GP G  G     GPMG RG       PGP G      
Sbjct: 1114 KPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETG 1173

Query: 864  ----PPGEQGLPGTAGKEGTKGDPGPPGAPGKDG---------PAGLRGFPGERGLPGTA 910
                PPG +G PG  G +G +G PG PG PG+ G         P G+ GFPG  GLPG  
Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233

Query: 911  --------GGPGLKGNEGPSGPPGPAGS--------------PGERGAAGSGGPIGPPGR 948
                    G PG +G+ G  GPPGP GS              PG +G  G+ G +GPPGR
Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293

Query: 949  ---------PGPQGPPGAAGEKGVPGEKG------------PIGPTGRDGVQGPVG---- 983
                     PGP+G PG  G  GV GEKG            PIGP G  GV+G  G    
Sbjct: 1294 LGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKI 1353

Query: 984  --LPGPAGPPGVAGEDGDKGEVGDPGQKGT------KGNKGEHGPPGPPGPIGPVG---- 1031
              LPG  GPPG  GE G +GE G PG  G       +G  G+ G PG PGP G  G    
Sbjct: 1354 ISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGS 1413

Query: 1032 --QPGAAGADGEPGARGPQGHFGAKGDEGTRGF 1062
              +PG AG+DG PG +G +G  G+     TRGF
Sbjct: 1414 KGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGF 1446



 Score =  368 bits (945), Expect = e-101
 Identities = 255/627 (40%), Positives = 279/627 (44%), Gaps = 122/627 (19%)

Query: 936  AAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP---PG 992
            AA  G      G+    G  G  GEKG P   GP G  G+ G  GP GLPGP GP   PG
Sbjct: 26   AASKGCVCKDKGQCFCDGAKGEKGEKGFP---GPPGSPGQKGFTGPEGLPGPQGPKGFPG 82

Query: 993  VAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGE---PGARGPQG 1049
            + G  G KG  G  G  G  G+ G  G PG  GP G VG PG +G+ GE   PG  G  G
Sbjct: 83   LPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLG 142

Query: 1050 HFGAKGDEGTRGFNGPP-----------GPIGLQGLPGPSGEKGETGDVGPMGPPGPP-- 1096
            + G  G  G +G  G P           G  GL G PGP G  G  G  GP+GPPGPP  
Sbjct: 143  YPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGF 202

Query: 1097 -------GPRGP--------------AGPNGADGPQGPPGGV------------------ 1117
                   GPRGP               G  G  GP GPPG V                  
Sbjct: 203  FGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKG 262

Query: 1118 -----GNLGPPGEKGEPGES--------GSPGIQGEP---GVKGPRGERGEKGESGQPGE 1161
                 G  GPPG  G PGES        G PG+QG+P   GV G  G  G KG  G PG 
Sbjct: 263  DKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGL 322

Query: 1162 PGPPGPKGPTGDDGPKGNPGPVGF------PGDPGPPGEGGPRGQDGAKGDRGEDGEPGQ 1215
             G  G KG  GD GP G  GP  +       GD G PG  GPRG  G +G  G  G PG 
Sbjct: 323  MGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGS 382

Query: 1216 PGS--PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA 1273
            PGS  PG  G  G PG  G +G  G PG +      G  G PG  G+PG  G  GP GP 
Sbjct: 383  PGSSRPGLRGAPGWPGLKGSKGERGRPGKD----AMGTPGSPGCAGSPGLPGSPGPPGPP 438

Query: 1274 G----KPGPDGLRGLPGSVGQQGRPGATGQAGP-----------PGPVGPPGLPGLRGDA 1318
            G    + GP G  GLPG +G  G PG  G  G            PGP G PGLPGL G  
Sbjct: 439  GDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVK 498

Query: 1319 GAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGE----------MGIPGASGP 1368
            G  G +G  GL G  G PG  G  G  G PG QG PG KGE          +G+PG  G 
Sbjct: 499  GIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGL 558

Query: 1369 IGPGGPPGLPGPAGPKGAKGATGPGGP---KGEKGVQGPPGHPGPPGEVIQPLPIQMPKK 1425
             G  G  GL G  G  G KG  GP G     GEKG QGPPG PG PG    P P      
Sbjct: 559  RGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPG---SPGPAGPAGP 615

Query: 1426 TRRSVDGSRLMQEDEAIPTGGAPGSPG 1452
                  G   +Q  + +P  GAPG PG
Sbjct: 616  PGYGPQGEPGLQGTQGVP--GAPGPPG 640



 Score =  354 bits (908), Expect = 4e-97
 Identities = 222/544 (40%), Positives = 270/544 (49%), Gaps = 57/544 (10%)

Query: 259  QNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGML-VEGPPGP 317
            + ++    +P P E   ++     P L+  A  P G KG +G P +  PG+  ++G PGP
Sbjct: 933  KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP-GEKGNRGVPGM--PGLKGLKGLPGP 989

Query: 318  EGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--- 374
             GP G  G  G  GNPG   +PG RG PG  G  G  G+ G  GT L  P R G  G   
Sbjct: 990  AGPPGPRGDLGSTGNPG---EPGLRGIPGSMGNMGMPGSKGKRGT-LGFPGRAGRPGLPG 1045

Query: 375  -----GDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGD 429
                 GDKG    ++  +             GPPGP G  G PG +G+ G  G  G  G 
Sbjct: 1046 IHGLQGDKGEPGYSEGTRP------------GPPGPTGDPGLPGDMGKKGEMGQPGPPGH 1093

Query: 430  LGPQGPRGPQGLTGPPG---KAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGH 486
            LGP GP G  G  G PG   K G  G  G  G +G+ G PG++G  G  G PG PG  G 
Sbjct: 1094 LGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGI 1153

Query: 487  RGDTGAQGLPGPPGEDGERGD-DGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDG 545
            RGD G  G+PGP GE GE G      GPRG PG  G +G    +G PG PG PG +G  G
Sbjct: 1154 RGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKG---DRGAPGFPGLPGRKGAMG 1210

Query: 546  PQGPKGSLGPQGEPGPPGQQGT--PGTQGLPGPQGAIGPHGEKGPQGKPG--LPGMPGSD 601
              GP+G  G +G PGPPG  G   PG  G  GP G+ G  G  GP G PG  + G+ G  
Sbjct: 1211 DAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDK 1270

Query: 602  GPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF- 660
            G  GHPG +GPPGT G+ GP G  G  G PG  G +G  G +G  G KGEKG  GF G  
Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSI 1330

Query: 661  --------KGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVP 712
                    KG  GV+GD G + +    G  GP G  G  G  G+PGPPG  G  G  G  
Sbjct: 1331 GPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPR 1390

Query: 713  GLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKS 772
            G PG  G+         PG PG +GEKG +G  G+ GP G  G  G +G+RG  G+    
Sbjct: 1391 GKPGKDGK---------PGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATW 1441

Query: 773  GAKG 776
              +G
Sbjct: 1442 TTRG 1445



 Score =  157 bits (396), Expect = 1e-37
 Identities = 109/293 (37%), Positives = 137/293 (46%), Gaps = 32/293 (10%)

Query: 264  QSQDPTPGEEEEILESSLL--PPLEEAAHGPRGLKGEKGEPAVLEPGML----VEGPPGP 317
            Q +D  PG   E  E+ LL  PP      G +G KG++G P    PG+       G  GP
Sbjct: 1157 QGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGF--PGLPGRKGAMGDAGP 1214

Query: 318  EGPAGLIGPPGIQGNPGPV--GDPGERGPPGRAGLPGSDGAPGPPGTSLM-LPFRFGSGG 374
             GP G+ G PG  G PG +  G  G RGPPG  G PG+ G PGPPG+ ++ +    GS G
Sbjct: 1215 RGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMG 1274

Query: 375  --GDKGPVVAAQEAQAQAIL-QQARLALRGP------------------PGPMGYTGRPG 413
              G KGP   A +      L       L GP                  PG +G  G PG
Sbjct: 1275 HPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPG 1334

Query: 414  PLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRG 473
            P+G  G PG++G+ G L      G  G  G PG+ G +G  G  G  G  G  G +G  G
Sbjct: 1335 PIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPG 1394

Query: 474  FDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLL 526
             DG PG PG  G +G+ G++G PGP G DG  G  G+ G  G P     RG +
Sbjct: 1395 KDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGFV 1447


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
            sapiens]
          Length = 1670

 Score =  894 bits (2311), Expect = 0.0
 Identities = 580/1363 (42%), Positives = 670/1363 (49%), Gaps = 260/1363 (19%)

Query: 291  GPRGLKGEKGEPAVL-EPGML----VEGPPGPEGPAG---------------LIGPPGIQ 330
            G +G KGEKG P     PG       EG PGP+GP G               + G PG  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 331  GNPGPVGDPGERGPPGRAGLPGSDGA------PGPPGTSLMLPFRFGSGG--GDKGPVVA 382
            G+PG  G PG  GP G  G+PG  G+      PG PGT L  P   G+ G  G KG    
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGT-LGYPGIPGAAGLKGQKGAPAK 161

Query: 383  AQEAQAQAILQQARLALRGPPGPMGYTGRPG---PLGQPGSPGLKGESGDLGPQGP---- 435
             ++ +  A   +    L G PGP G  G PG   P+G PG PG  G  G +GP+GP    
Sbjct: 162  EEDIELDA---KGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHM 218

Query: 436  ----------RGPQGLTGPPGKAGR--------------RGRAGADGA------------ 459
                      RG +GLTGPPG  G               +G  G  GA            
Sbjct: 219  GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGL 278

Query: 460  --------RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI 511
                    +G PGDPG++G  G DG+PG PG +G +G+   +G PG  GEDG +G  G+I
Sbjct: 279  PGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN---RGFPGLMGEDGIKGQKGDI 335

Query: 512  GP------------------RGLPGESGPRGLLGPKGP---PGIPGPPG-----VRGMDG 545
            GP                   G PG  GPRG  GP+GP   PG+PG PG     +RG  G
Sbjct: 336  GPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPG 395

Query: 546  PQGPKGSLGPQGEPGP-----PGQQGTPGTQGLPGPQGAIGPHGE----KGPQGKPGLPG 596
              G KGS G +G PG      PG  G  G+ GLPG  G  GP G+    KGP G  GLPG
Sbjct: 396  WPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPG 455

Query: 597  MPGSDGPPGHPGKEGPPGTKGNQGP--SGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGE 654
              GS G PG  G +G PG    Q P   GP G  G PG  GVKG+ G +G  G KG  G 
Sbjct: 456  YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515

Query: 655  DG---------FPGFKGDIGVKGDRGE-------VGVPGSRGEDGPEGPKGRTGPTGDPG 698
             G         FPG +GD G+KG++GE       VGVPG  G  G  G KG  G  G PG
Sbjct: 516  PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575

Query: 699  PPGLMGEKGKL------------GVPGLPGYPGRQGPKGSLGF-----PGFPGASGEKGA 741
              GL G KG+L            G PG PG PG  GP G  G+     PG  G  G  GA
Sbjct: 576  VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635

Query: 742  RGLSGKSGPRGER----------GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG 791
             G  G++GPRGE           GP GP G  GP+G  G  G+ G  G  G  GP GE G
Sbjct: 636  PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPG 695

Query: 792  LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP--------PGVVGP 843
            +PG   P G PGPKG  G PG  G  G PG+ GE G  GK G PG         PG  G 
Sbjct: 696  IPGIGFP-GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGT 754

Query: 844  QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE 903
             G  GE G  GE G  G PG PG  G PG  G +G +GDPG PG PG+ GP G R   G 
Sbjct: 755  PGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPG-RCIEGP 813

Query: 904  RGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSG--GPIGPPGRPGPQGPPGAAGEK 961
            RG  G  G  GLKG +G  G  GP G PG  G   SG  G  G PG PG QG  G  G++
Sbjct: 814  RGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQR 873

Query: 962  GVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPG------QKGTKGNK 1015
            G PG  G +GP G DGV G +G PG  GPPG  G  G  G+ G PG      Q+GT G K
Sbjct: 874  GYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAK 933

Query: 1016 GEHGPPGPPGP------IGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPI 1069
            GE G  G PGP      IG  G+PG  G  G PG            ++G RG  G PG  
Sbjct: 934  GEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPG------------EKGNRGVPGMPGLK 981

Query: 1070 GLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP 1129
            GL+GLPGP+G  G  GD+G  G PG PG RG  G  G  G  G  G  G LG PG  G P
Sbjct: 982  GLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRP 1041

Query: 1130 GESGSPGIQGE-----------PGVKGPRGERG---EKGESGQPGEPGPPGPKGPTGDDG 1175
            G  G  G+QG+           PG  GP G+ G   + G+ G+ G+PGPPG  GP G +G
Sbjct: 1042 GLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101

Query: 1176 PKGNPGPVGFPGDPGPPGEGGPRGQDGAKGD---RGEDGEPGQPGSPGPTG------ENG 1226
              G+PG  G PG PGP G+ G +G  G  G    RG  G PG PGSPGP G       +G
Sbjct: 1102 APGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDG 1161

Query: 1227 PPGPLGKRGPAG----SPGSEGRQGGKGAKGD---------PGAIGAPGKTGPVGPAGPA 1273
             PGP G++G  G     PG  G  G +GAKGD         PG  GA G  GP GP G  
Sbjct: 1162 IPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIE 1221

Query: 1274 GKPGPDGLRG--LPGSVGQQGRPGATGQAGPPGPVGPPG--LPGLRGDAGAKGE---KGH 1326
            G PGP GL G  +PG  G +G PG+ G  G PGP GPPG  + G++GD G+ G    KG 
Sbjct: 1222 GFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP 1281

Query: 1327 PGLIGLIGPPGEQGEKGDRGLPGP------QGSPGQKGEMGIPGASGPIGPGGPPGLPGP 1380
            PG  G +GPPG  G  G  GLPGP      QG PG KGE G PG  G IGP GP G  GP
Sbjct: 1282 PGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGP 1341

Query: 1381 AGPKG---------AKGATGPGGPKGEKGVQGPPGHPGPPGEV 1414
             G +G           G+ GP G  GE G+QG PG PGPPG +
Sbjct: 1342 PGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNL 1384



 Score =  877 bits (2267), Expect = 0.0
 Identities = 556/1317 (42%), Positives = 647/1317 (49%), Gaps = 201/1317 (15%)

Query: 264  QSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGL 323
            + Q   P +EE+I   +   P    A GP+GL G  G P          GP GP GP G 
Sbjct: 153  KGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFP----------GPVGPPGPPGF 202

Query: 324  IGPPGIQGNPGPVGDPGER--GPPGRAGLPGSDGAPGPPGTSLML----PFRFGSGG--G 375
             G PG  G  GP G  GER  G  G  G+ G  G PGPPGT ++       R    G  G
Sbjct: 203  FGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKG 262

Query: 376  DKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPG------------- 422
            DKG +          +  ++  + +G PG  G  G+PG  G PG PG             
Sbjct: 263  DKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGL 322

Query: 423  -----LKGESGDLGPQGPRGP------------QGLTGPPGKAGRRGRAGADGARGMPGD 465
                 +KG+ GD+GP G RGP            +G  GPPG  G RG  G  G  G+PG 
Sbjct: 323  MGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGS 382

Query: 466  PGVK--GDRGFDGLPGLPGEKGHRGD--------------TGAQGLPGPPGEDGERGD-- 507
            PG    G RG  G PGL G KG RG                G+ GLPG PG  G  GD  
Sbjct: 383  PGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIV 442

Query: 508  -----------DGEIGPRGLPGESGPRGLLGP--------KGPPGIPGPPGVRGMDGPQG 548
                        G +G  G+PG  GP+G  G          GPPG+PG PG+ G+ G  G
Sbjct: 443  FRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPG 502

Query: 549  PKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKG----PQGKPGLPGMPGSDGPP 604
             +G+ G +G PG PG  G PG  G PG QG  G  GEKG    P+G+ G+PG PG  G P
Sbjct: 503  RQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQP 562

Query: 605  GHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF--KG 662
            G  G +G PGT G +G  GP+G L   G +G +G  G  G  G  G  G  G PG+  +G
Sbjct: 563  GRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQG 622

Query: 663  DIGVKGDRGEVGVPGSRGEDGPEG----------PKGRTGPTGDPGP---PGLMGEKGKL 709
            + G++G +G  G PG  GE GP G          P G  GP G PGP   PG+ G  GK 
Sbjct: 623  EPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKC 682

Query: 710  GVPGLPG-----------YPGRQGPKGSLGFPGFPGA---SGEKGARGLSGKSGPRGERG 755
            G PGLPG           +PG  GPKG  GFPG  G+    G+ G  GL GK G  G +G
Sbjct: 683  GDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKG 742

Query: 756  ------PTGPR--GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP 807
                  P GP   G  G RG +G+ G  G  G  G  G PG  GL GP+G  G PGP G 
Sbjct: 743  EPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGE 802

Query: 808  PGPPGK--------DGLPGHPGQRGEVGFQGKTGPPGPPGVVG--PQGAAGETGPMGERG 857
             GPPG+         GLPG  G +G+ G +GKTGP G PG+ G    G  GETG  G  G
Sbjct: 803  QGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPG 862

Query: 858  HPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKG 917
            H G  GP G++G PG         +PG  G PG+DG  G+ GFPG  G PG  G PG  G
Sbjct: 863  HQGEMGPLGQRGYPG---------NPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPG 913

Query: 918  NEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP------GPQGPPGAAGEKGVPGEKGPIG 971
              G  G PG  G  G  GA G  G  G PG        G +G PG  G  G PGEKG  G
Sbjct: 914  QRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRG 973

Query: 972  PTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVG 1031
              G  G++G  GLPGPAGPPG  G+ G  G  G+PG +G  G+ G  G PG  G  G +G
Sbjct: 974  VPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLG 1033

Query: 1032 QPGAAGADGEPGARGPQGHFGAKG-DEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPM 1090
             PG AG  G PG  G QG  G  G  EGTR   GPPGP G  GLPG  G+KGE      M
Sbjct: 1034 FPGRAGRPGLPGIHGLQGDKGEPGYSEGTRP--GPPGPTGDPGLPGDMGKKGE------M 1085

Query: 1091 GPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKG---------EPGESGSPGIQGEP 1141
            G PGPPG  GPAGP GA G  G PG  G  GP G+ G          PG  G PG+ G P
Sbjct: 1086 GQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFP 1145

Query: 1142 GVKGPRGERGEKGESGQPGEPG----------PPGPKGPTGDDGPKGNPGPVGFPGDPGP 1191
            G  GP G RG++G  G PG  G          PPGP+G  G  G KG+ G  GFPG PG 
Sbjct: 1146 GSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGR 1205

Query: 1192 PGEGGPRGQDGAKGDRGEDGEPGQPGS--PGPTGENGPPGPLGKRG---PAGSPGSE--G 1244
             G  G  G  G  G  G  G PG PG+  PG TG  GPPG  G  G   P G PGS   G
Sbjct: 1206 KGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIG 1265

Query: 1245 RQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL---------RGLPGSVGQQGRPG 1295
             +G KG+ G PG  G PG  G +GP G  G PG  GL         +G PG  G++G PG
Sbjct: 1266 IKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG 1325

Query: 1296 ATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPG 1355
              G  GPPGP+GP G PG+RGD G       PG  G  G PGE G +G+ G PGP G+ G
Sbjct: 1326 FLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLG 1385

Query: 1356 QKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1412
              G  G PG        G PG PGPAG KG KG+ G  GP G  G+ G  G  G  G
Sbjct: 1386 PCGPRGKPGKD------GKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSG 1436



 Score =  831 bits (2146), Expect = 0.0
 Identities = 509/1147 (44%), Positives = 580/1147 (50%), Gaps = 97/1147 (8%)

Query: 291  GPRGLKGEKGEPAVLEPGMLVE-----------GPPGPEG---PAGLIGPPGIQGNPGPV 336
            G +G KG+ G P    P    +           GPPGP G   P G  GPPG+ G+PG  
Sbjct: 327  GIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGS- 385

Query: 337  GDPGERGPPGRAGLPGSDGAPGPPGTSLM-LPFRFGSGGGDKGPVVAAQEAQAQAILQQA 395
              PG RG PG  GL GS G  G PG   M  P   G  G    P           I+ + 
Sbjct: 386  SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFR- 444

Query: 396  RLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPR--GPQGLTGPPGKAGRRGR 453
                +GPPG  G  G  G  G PG  G KGE G L  Q P   GP GL G PG  G +G 
Sbjct: 445  ----KGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGI 500

Query: 454  AGADGARGMPGDPGVKGDRGFDGLPGLPGE------KGHRGDT-GAQGLPGPPGEDGERG 506
             G  GA G+ G PG  G+ G  G PG PG       KG +G+T   +G  G PG+ G RG
Sbjct: 501  PGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRG 560

Query: 507  DDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQ-- 564
              G  G  G+PG  G +GL GPKG   + G  G +G  G  G  GS GP G  GPPG   
Sbjct: 561  QPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGP 620

Query: 565  QGTPGTQGLPGPQGAIGPHGEKGPQGKPGL----PGMPGSDGPPGHPGKEGPPGTKGNQG 620
            QG PG QG  G  GA GP GE GP+G+  +    PG PG  GPPGHPG +GPPG  G+ G
Sbjct: 621  QGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLG 680

Query: 621  PSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRG 680
              G  G    PGP G  G+ GI G  G  G KG+ GFPG KG +G  G  GE G+PG  G
Sbjct: 681  KCGDPG---LPGPDGEPGIPGI-GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPG 736

Query: 681  EDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKG 740
              G +G      P G PG PG  GE+G  G  G  G PG  G       PG PG  G  G
Sbjct: 737  LPGAKGEPAVAMP-GGPGTPGFPGERGNSGEHGEIGLPGLPG------LPGTPGNEGLDG 789

Query: 741  ARGLSGKSGPRGERGPTGP--RGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGP 798
             RG  G+ GP GE+GP G    G RG +G  G +G KG  G  G  GP G+ G+PG    
Sbjct: 790  PRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDR- 848

Query: 799  NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP---------PGVVGPQGAAGE 849
            +GFPG  G PG PG  G  G  GQRG  G  G  GPPG          PG +GP G  G 
Sbjct: 849  SGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGN 908

Query: 850  TGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP---GKDGPAGLRGFPGERGL 906
             G  G+RG PG PG  G++G PG  G++G KG+PGP       G  G  GL+GF G  G 
Sbjct: 909  PGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGE 968

Query: 907  PGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGE 966
             G  G PG+ G +G  G PGPAG PG RG  GS    G PG PG +G PG+ G  G+PG 
Sbjct: 969  KGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS---TGNPGEPGLRGIPGSMGNMGMPGS 1025

Query: 967  KGPIGPTGRDGVQGPVGLPGPAGPPGVAGE--------DGDKGEVGDPGQKGTKGNKGEH 1018
            KG  G  G  G  G  GLPG  G  G  GE         G  G  GDPG  G  G KGE 
Sbjct: 1026 KGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEM 1085

Query: 1019 GPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP---GPIGLQGLP 1075
            G PGPPG +GP G  GA G+ G PG  G  G  G  G +G +G  GPP   GP GL G P
Sbjct: 1086 GQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFP 1145

Query: 1076 GPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSP 1135
            G  G  G  GD G  G PGP G +G  G   A     PPG  GN G  G KG+ G  G P
Sbjct: 1146 GSPGPMGIRGDQGRDGIPGPAGEKGETGLLRA-----PPGPRGNPGAQGAKGDRGAPGFP 1200

Query: 1136 GIQGEPGVKGPRGERGEKGESGQPGEPGPPGP--KGPTGDDGPKGNPGPVGFPGDPGPPG 1193
            G+ G  G  G  G RG  G  G PG PG PG    G TG+ GP G+ G  G PG PGPPG
Sbjct: 1201 GLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPG 1260

Query: 1194 EG--GPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGA 1251
                G +G  G+ G  G  G PG  G  GP G  G PG  G  GP G PG +G  G KG 
Sbjct: 1261 SHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGE 1320

Query: 1252 KGDPGAIGAPGKTGPVGPAGPAGKPGPDG---LRGLPGSVGQQGRPGATGQAGPPGPVGP 1308
            KG+PG +G+ G  GP+GP GP G  G  G   +  LPGS G  G PG  G  G PGP GP
Sbjct: 1321 KGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGP 1380

Query: 1309 PGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGP 1368
            PG  G  G  G  G+ G P   G  GP GE+G KG +G PGP GS       G+PG  G 
Sbjct: 1381 PGNLGPCGPRGKPGKDGKP---GTPGPAGEKGNKGSKGEPGPAGSD------GLPGLKGK 1431

Query: 1369 IGPGGPP 1375
             G  G P
Sbjct: 1432 RGDSGSP 1438



 Score =  804 bits (2077), Expect = 0.0
 Identities = 516/1242 (41%), Positives = 594/1242 (47%), Gaps = 217/1242 (17%)

Query: 401  GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGAR 460
            G  G  G  G PGP G PG  G  G  G  GPQGP+G  GL G  G  G RG +G  G  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 461  GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 520
            G PG PG  G+ G  GL G+PG  G +G+ G  GLPG  G  G  G  G  G +G P + 
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 521  GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQG-- 578
                L   KG PG+PG PG +G+ GP G  G +GP   PGPPG  G PG  G  GP+G  
Sbjct: 163  EDIEL-DAKGDPGLPGAPGPQGLPGPPGFPGPVGP---PGPPGFFGFPGAMGPRGPKGHM 218

Query: 579  ---AIGPHGEKGPQGKPGLPGMPGS-----DGPPGHPGKEGPPGTKGNQGPSGPQGPLGY 630
                IG  GE+G +G  G PG PG+      GP      +G  G KG  G  GP GP G 
Sbjct: 219  GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGL 278

Query: 631  PGP--------------RGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVP 676
            PG               +G  G DG+ G  G +G KG  GFPG  G+ G+KG +G++G P
Sbjct: 279  PGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPP 338

Query: 677  GSRGED---------------GPEGPKGRTGPTGDPGPPGLMGEKG--KLGVPGLPGYPG 719
            G RG                 GP GP+G  GP G  GPPG+ G  G  + G+ G PG+PG
Sbjct: 339  GFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPG 398

Query: 720  RQGPKG--------SLGFPGFPGASGEKGARGLSGKSGPRGE----RGPTGPRGQRGPRG 767
             +G KG        ++G PG PG +G  G  G  G  GP G+    +GP G  G  G  G
Sbjct: 399  LKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLG 458

Query: 768  ATGKSGAKGTSGGDG------PH--GPPGERGLPGPQGPNGFPGP------KGPPGPPGK 813
            + G  G  G  G  G      P+  GPPG  GLPG  G  G PG       KG PG PG 
Sbjct: 459  SPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGN 518

Query: 814  DGLPGHPGQRGEVGFQGKTGPPG----PPGVVGPQGAAGETGPMGERGHPGPPGPPGEQG 869
             GLPG PG  G  G  G  G  G    P G VG  G  G  G  G +G  G PG PG +G
Sbjct: 519  TGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKG 578

Query: 870  LPGT------AGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSG 923
            LPG       +G++G +G PG PG+PG  GPAG  G PG     G  G PGL+G +G  G
Sbjct: 579  LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY----GPQGEPGLQGTQGVPG 634

Query: 924  PPGPAGSPGERG-------AAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD 976
             PGP G  G RG         G  GP GPPG PGPQGPPG  G  G  G+ G  GP G  
Sbjct: 635  APGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEP 694

Query: 977  GVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGT------------------------- 1011
            G+ G +G PGP GP G  G  G KG +G PG+ G                          
Sbjct: 695  GIPG-IGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPG 753

Query: 1012 -------KGNKGEHGP---------PGPPG------PIGPVGQPGAAGADGEPG------ 1043
                   +GN GEHG          PG PG      P G  GQPG  G  G PG      
Sbjct: 754  TPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGP 813

Query: 1044 --ARGPQGHFGAKGDEGTRGFNGPPGPIGLQGL-----------PGPSGEKGETGDVGPM 1090
              A+G  G  G KG +G RG  GP G  G+ GL           PG  G +GE G +G  
Sbjct: 814  RGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQR 873

Query: 1091 GPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGER 1150
            G PG PG  GP G +G  G  G PG +G  GPPG  G PG+ GSPGI   PGVKG RG  
Sbjct: 874  GYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGI---PGVKGQRGTP 930

Query: 1151 GEKGESGQPGEPGP------------PGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPR 1198
            G KGE G  G PGP            PG KG  G+ G KGN G  G PG  G  G  GP 
Sbjct: 931  GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPA 990

Query: 1199 GQDGAKGDRGEDGEPGQPGS---PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDP 1255
            G  G +GD G  G PG+PG    PG  G  G PG  GKRG  G PG  GR G  G  G  
Sbjct: 991  GPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQ 1050

Query: 1256 GAIGAPGKTGPV--GPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG 1313
            G  G PG +     GP GP G PG  G  G  G +GQ G PG  G AGP G  G PG PG
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 1314 LRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPG---PQGSPGQKGEMGIPGASGPIG 1370
            L G  G  G+ G  G+ GL+GPPG +G  G  G PG   P G  G +G  GIPG +G  G
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170

Query: 1371 -------PGGPPGLPGPAGPK------------GAKGATGPGGPKGEKGVQGPPGHPGPP 1411
                   P GP G PG  G K            G KGA G  GP+G  G++G PG PG P
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 1412 GEVIQPLPIQMPKKT-RRSVDGSRLMQEDEAIPTGGAPGSPG 1452
            G +I       P +T  R   GSR         + GAPG PG
Sbjct: 1231 GAII-------PGQTGNRGPPGSR--------GSPGAPGPPG 1257



 Score =  744 bits (1921), Expect = 0.0
 Identities = 463/1087 (42%), Positives = 537/1087 (49%), Gaps = 113/1087 (10%)

Query: 263  PQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAG 322
            PQ     PG        S  P L  A   P GLKG KGE     PG    G PG  G AG
Sbjct: 370  PQGPSGPPGVPGS--PGSSRPGLRGAPGWP-GLKGSKGERG--RPGKDAMGTPGSPGCAG 424

Query: 323  LIGPPGIQGNPGPVGD-------PGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGG 375
              G PG  G PGP GD       PG+ G PG  G PG  G  GP G   +L  +     G
Sbjct: 425  SPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPG 484

Query: 376  DKG-PVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGS---PGLKGESGDL- 430
              G P +           +Q    L+G PG  G TG PG  G PG+   PGLKGE G+  
Sbjct: 485  PPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETL 544

Query: 431  ---GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG---VKGDRGFDGLPGLPGEK 484
               G  G  G  GL G PG+ G  G  G  G +G+PG  G   + G++G  G PG PG  
Sbjct: 545  QPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSP 604

Query: 485  GHRGDTGAQGLPG--PPGEDGERGDDGEIGPRGLPGESGPRGLLGPK----GPPGIPGPP 538
            G  G  G  G PG  P GE G +G  G  G  G PGE+GPRG L       GPPG PGPP
Sbjct: 605  GSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664

Query: 539  GVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT--------------QGLPGPQGAIGPHG 584
            G  G  GP G  GSLG  G+PG PG  G PG               QG PG +G++G  G
Sbjct: 665  GHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPG 724

Query: 585  EKGPQGKPGLPGMPGSDGPPG--HPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGI 642
            + G  G PG PG+PG+ G P    PG  G PG  G +G SG  G +G PG  G+ G  G 
Sbjct: 725  KMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGN 784

Query: 643  RGLKGHKGEKGEDGFPGFKGDIG--VKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPP 700
             GL G +G+ G+ G PG +G  G  ++G RG  G+PG  G  G +G +G+TGP GDPG P
Sbjct: 785  EGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIP 844

Query: 701  GL--MGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTG 758
            GL   G  G+ G PG+PG+ G  GP G  G+PG PG  G  G  G+ G  G  G  GP G
Sbjct: 845  GLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPG 904

Query: 759  PRGQRGP---RGATGKSGAKGTSGGDGPHGPPGERGLPGPQ------GPNGFPGPKGPPG 809
            P G  G    RG+ G  G KG  G  G  G  G++G PGP       G  G PG KG  G
Sbjct: 905  PPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAG 964

Query: 810  PPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQG 869
             PG+ G  G PG  G  G +G  GP GPPG   P+G  G TG  GE G  G PG  G  G
Sbjct: 965  NPGEKGNRGVPGMPGLKGLKGLPGPAGPPG---PRGDLGSTGNPGEPGLRGIPGSMGNMG 1021

Query: 870  LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGL--------PGTAGGPGLKGNEGP 921
            +PG+ GK GT G PG  G PG  G  GL+G  GE G         PG  G PGL G+ G 
Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGK 1081

Query: 922  SGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGP 981
             G  G  G PG  G AG  G  G PG PG  G PG  G+ G  G KG +GP G   ++GP
Sbjct: 1082 KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPG---IRGP 1138

Query: 982  VGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE-HGPPGPPGPIGPVGQPGAAGADG 1040
             GLPG  G PG  G  GD+G  G PG  G KG  G    PPGP G  G  G  G  GA G
Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG 1198

Query: 1041 EPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQG--LPGPSGEKGETGDVGPMGPPGPPGP 1098
             PG  G +G  G  G  G  G  G PGP GL G  +PG +G +G  G  G  G PGPPGP
Sbjct: 1199 FPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGP 1258

Query: 1099 --------RGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGER 1150
                    +G  G  G  GP+GPPG  G++GPPG  G PG  G PG +G+PG +G  G +
Sbjct: 1259 PGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVK 1318

Query: 1151 GEKGESG------------------------------QPGEPGPPGPKGPTGDDGPKGNP 1180
            GEKG  G                               PG PGPPG  G  G  G  G P
Sbjct: 1319 GEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPP 1378

Query: 1181 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1240
            GP G  G  GP G+ G  G+ G  G  GE G  G  G PGP G +G PG  GKRG +GSP
Sbjct: 1379 GPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438

Query: 1241 GSEGRQG 1247
             +   +G
Sbjct: 1439 ATWTTRG 1445



 Score =  617 bits (1590), Expect = e-176
 Identities = 389/933 (41%), Positives = 463/933 (49%), Gaps = 175/933 (18%)

Query: 289  AHGPRGLKGEKGEPAVLE--------PGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGD-- 338
            A G  GLKGEKGE    E        PG+   G PG +G  G+ G PG++G PGP G+  
Sbjct: 530  AQGDPGLKGEKGETLQPEGQVGVPGDPGL--RGQPGRKGLDGIPGTPGVKGLPGPKGELA 587

Query: 339  ----PGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--------GDKGPVVAAQEA 386
                 G++GPPG  G PGS G  GP G     P  +G  G        G  G      EA
Sbjct: 588  LSGEKGDQGPPGDPGSPGSPGPAGPAG-----PPGYGPQGEPGLQGTQGVPGAPGPPGEA 642

Query: 387  QAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLG--------------- 431
              +  L  +   + GPPGP G  G PGP G PG PG  G+ GD G               
Sbjct: 643  GPRGELSVST-PVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF 701

Query: 432  --PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDR-----GFDGLPGLPGEK 484
              P GP+G QG  G  G  G  G+ G  G  G PG PG KG+      G  G PG PGE+
Sbjct: 702  PGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGER 761

Query: 485  GHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGP-----KGPPGIPGPPG 539
            G+ G+ G  GLPG PG  G  G++G  GPRG PG+ GP G  GP     +GP G  G PG
Sbjct: 762  GNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPG 821

Query: 540  VRGMDGPQGPKGSLGPQGEPGPPGQQ-----GTPGTQGLPGPQGAIGPHGEKGPQGKPGL 594
            + G+ G QG +G  GP+G+PG PG       G  G+ G+PG QG +GP G++G  G PG+
Sbjct: 822  LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGI 881

Query: 595  PGMPGSDGP---PGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKG- 650
             G PG DG     G PG  GPPG  GN G  G +G  G PG +G +G  G +G +G KG 
Sbjct: 882  LGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGN 941

Query: 651  -----------EKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP 699
                       +KGE G  GF G+ G KG+RG  G+PG +G  G  GP G  GP GD G 
Sbjct: 942  PGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS 1001

Query: 700  PGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGP 759
             G  GE G  G+PG  G  G  G KG  G  GFPG +G  G  G+ G  G +GE G +  
Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYS-- 1059

Query: 760  RGQR-GPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPG 818
             G R GP G TG  G  G  G        GE G PGP G  G  GP+G PG PG  GLPG
Sbjct: 1060 EGTRPGPPGPTGDPGLPGDMG------KKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPG 1113

Query: 819  HPGQRGEVGFQGKTGPPGPPGVVGPQGAAG---ETGPMGERGH------PGPPG------ 863
             PG  G++GF+G  G  GPPG+ GP G  G     GPMG RG       PGP G      
Sbjct: 1114 KPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETG 1173

Query: 864  ----PPGEQGLPGTAGKEGTKGDPGPPGAPGKDG---------PAGLRGFPGERGLPGTA 910
                PPG +G PG  G +G +G PG PG PG+ G         P G+ GFPG  GLPG  
Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233

Query: 911  --------GGPGLKGNEGPSGPPGPAGS--------------PGERGAAGSGGPIGPPGR 948
                    G PG +G+ G  GPPGP GS              PG +G  G+ G +GPPGR
Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293

Query: 949  ---------PGPQGPPGAAGEKGVPGEKG------------PIGPTGRDGVQGPVG---- 983
                     PGP+G PG  G  GV GEKG            PIGP G  GV+G  G    
Sbjct: 1294 LGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKI 1353

Query: 984  --LPGPAGPPGVAGEDGDKGEVGDPGQKGT------KGNKGEHGPPGPPGPIGPVG---- 1031
              LPG  GPPG  GE G +GE G PG  G       +G  G+ G PG PGP G  G    
Sbjct: 1354 ISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGS 1413

Query: 1032 --QPGAAGADGEPGARGPQGHFGAKGDEGTRGF 1062
              +PG AG+DG PG +G +G  G+     TRGF
Sbjct: 1414 KGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGF 1446



 Score =  368 bits (945), Expect = e-101
 Identities = 255/627 (40%), Positives = 279/627 (44%), Gaps = 122/627 (19%)

Query: 936  AAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP---PG 992
            AA  G      G+    G  G  GEKG P   GP G  G+ G  GP GLPGP GP   PG
Sbjct: 26   AASKGCVCKDKGQCFCDGAKGEKGEKGFP---GPPGSPGQKGFTGPEGLPGPQGPKGFPG 82

Query: 993  VAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGE---PGARGPQG 1049
            + G  G KG  G  G  G  G+ G  G PG  GP G VG PG +G+ GE   PG  G  G
Sbjct: 83   LPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLG 142

Query: 1050 HFGAKGDEGTRGFNGPP-----------GPIGLQGLPGPSGEKGETGDVGPMGPPGPP-- 1096
            + G  G  G +G  G P           G  GL G PGP G  G  G  GP+GPPGPP  
Sbjct: 143  YPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGF 202

Query: 1097 -------GPRGP--------------AGPNGADGPQGPPGGV------------------ 1117
                   GPRGP               G  G  GP GPPG V                  
Sbjct: 203  FGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKG 262

Query: 1118 -----GNLGPPGEKGEPGES--------GSPGIQGEP---GVKGPRGERGEKGESGQPGE 1161
                 G  GPPG  G PGES        G PG+QG+P   GV G  G  G KG  G PG 
Sbjct: 263  DKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGL 322

Query: 1162 PGPPGPKGPTGDDGPKGNPGPVGF------PGDPGPPGEGGPRGQDGAKGDRGEDGEPGQ 1215
             G  G KG  GD GP G  GP  +       GD G PG  GPRG  G +G  G  G PG 
Sbjct: 323  MGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGS 382

Query: 1216 PGS--PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA 1273
            PGS  PG  G  G PG  G +G  G PG +      G  G PG  G+PG  G  GP GP 
Sbjct: 383  PGSSRPGLRGAPGWPGLKGSKGERGRPGKD----AMGTPGSPGCAGSPGLPGSPGPPGPP 438

Query: 1274 G----KPGPDGLRGLPGSVGQQGRPGATGQAGP-----------PGPVGPPGLPGLRGDA 1318
            G    + GP G  GLPG +G  G PG  G  G            PGP G PGLPGL G  
Sbjct: 439  GDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVK 498

Query: 1319 GAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGE----------MGIPGASGP 1368
            G  G +G  GL G  G PG  G  G  G PG QG PG KGE          +G+PG  G 
Sbjct: 499  GIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGL 558

Query: 1369 IGPGGPPGLPGPAGPKGAKGATGPGGP---KGEKGVQGPPGHPGPPGEVIQPLPIQMPKK 1425
             G  G  GL G  G  G KG  GP G     GEKG QGPPG PG PG    P P      
Sbjct: 559  RGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPG---SPGPAGPAGP 615

Query: 1426 TRRSVDGSRLMQEDEAIPTGGAPGSPG 1452
                  G   +Q  + +P  GAPG PG
Sbjct: 616  PGYGPQGEPGLQGTQGVP--GAPGPPG 640



 Score =  354 bits (908), Expect = 4e-97
 Identities = 222/544 (40%), Positives = 270/544 (49%), Gaps = 57/544 (10%)

Query: 259  QNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGML-VEGPPGP 317
            + ++    +P P E   ++     P L+  A  P G KG +G P +  PG+  ++G PGP
Sbjct: 933  KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP-GEKGNRGVPGM--PGLKGLKGLPGP 989

Query: 318  EGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--- 374
             GP G  G  G  GNPG   +PG RG PG  G  G  G+ G  GT L  P R G  G   
Sbjct: 990  AGPPGPRGDLGSTGNPG---EPGLRGIPGSMGNMGMPGSKGKRGT-LGFPGRAGRPGLPG 1045

Query: 375  -----GDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGD 429
                 GDKG    ++  +             GPPGP G  G PG +G+ G  G  G  G 
Sbjct: 1046 IHGLQGDKGEPGYSEGTRP------------GPPGPTGDPGLPGDMGKKGEMGQPGPPGH 1093

Query: 430  LGPQGPRGPQGLTGPPG---KAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGH 486
            LGP GP G  G  G PG   K G  G  G  G +G+ G PG++G  G  G PG PG  G 
Sbjct: 1094 LGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGI 1153

Query: 487  RGDTGAQGLPGPPGEDGERGD-DGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDG 545
            RGD G  G+PGP GE GE G      GPRG PG  G +G    +G PG PG PG +G  G
Sbjct: 1154 RGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKG---DRGAPGFPGLPGRKGAMG 1210

Query: 546  PQGPKGSLGPQGEPGPPGQQGT--PGTQGLPGPQGAIGPHGEKGPQGKPG--LPGMPGSD 601
              GP+G  G +G PGPPG  G   PG  G  GP G+ G  G  GP G PG  + G+ G  
Sbjct: 1211 DAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDK 1270

Query: 602  GPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF- 660
            G  GHPG +GPPGT G+ GP G  G  G PG  G +G  G +G  G KGEKG  GF G  
Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSI 1330

Query: 661  --------KGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVP 712
                    KG  GV+GD G + +    G  GP G  G  G  G+PGPPG  G  G  G  
Sbjct: 1331 GPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPR 1390

Query: 713  GLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKS 772
            G PG  G+         PG PG +GEKG +G  G+ GP G  G  G +G+RG  G+    
Sbjct: 1391 GKPGKDGK---------PGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATW 1441

Query: 773  GAKG 776
              +G
Sbjct: 1442 TTRG 1445



 Score =  157 bits (396), Expect = 1e-37
 Identities = 109/293 (37%), Positives = 137/293 (46%), Gaps = 32/293 (10%)

Query: 264  QSQDPTPGEEEEILESSLL--PPLEEAAHGPRGLKGEKGEPAVLEPGML----VEGPPGP 317
            Q +D  PG   E  E+ LL  PP      G +G KG++G P    PG+       G  GP
Sbjct: 1157 QGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGF--PGLPGRKGAMGDAGP 1214

Query: 318  EGPAGLIGPPGIQGNPGPV--GDPGERGPPGRAGLPGSDGAPGPPGTSLM-LPFRFGSGG 374
             GP G+ G PG  G PG +  G  G RGPPG  G PG+ G PGPPG+ ++ +    GS G
Sbjct: 1215 RGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMG 1274

Query: 375  --GDKGPVVAAQEAQAQAIL-QQARLALRGP------------------PGPMGYTGRPG 413
              G KGP   A +      L       L GP                  PG +G  G PG
Sbjct: 1275 HPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPG 1334

Query: 414  PLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRG 473
            P+G  G PG++G+ G L      G  G  G PG+ G +G  G  G  G  G  G +G  G
Sbjct: 1335 PIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPG 1394

Query: 474  FDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLL 526
             DG PG PG  G +G+ G++G PGP G DG  G  G+ G  G P     RG +
Sbjct: 1395 KDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGFV 1447


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score =  885 bits (2288), Expect = 0.0
 Identities = 573/1389 (41%), Positives = 650/1389 (46%), Gaps = 272/1389 (19%)

Query: 289  AHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA 348
            A GP GL GEKG      P     G  G +GP G+ G PG+ G PG  G PG RG PG +
Sbjct: 81   APGPIGLSGEKGMRGDRGPPGAA-GDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMS 139

Query: 349  GLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQAR------------ 396
            G  GS G PG PG    L    G GG    P    ++  +  IL   +            
Sbjct: 140  GHNGSRGDPGFPGGRGAL----GPGGPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLP 195

Query: 397  -----LALRGPPGPMGYTGRPG---PLGQPGSPGLKG-----------ESGDLGPQGPRG 437
                     GP GP GY G PG   P GQPG PGLKG           + G++G QG  G
Sbjct: 196  GLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPG 255

Query: 438  PQ------------------------GLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRG 473
            P                         GL GPPG+ G  G  GA G +G+PG PG +GD G
Sbjct: 256  PTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESG-IGAKGEKGIPGFPGPRGDPG 314

Query: 474  FDGLPGLPGEKGH---------------RGDTGAQGLPGPPG------------------ 500
              G PG PG KG                +GD G +G PGPPG                  
Sbjct: 315  SYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGF 374

Query: 501  --EDGERGDDGEIGPRGLPGESGPR--GLLGPKGPPGIPGPPGVRGMDG-PQGPKGSLGP 555
                GE GD G  GP GL G  G    G++GP GP G PG PG+ G  G P  P  + G 
Sbjct: 375  PGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGK 434

Query: 556  QGEPGPPGQQGTPGTQGLPG---------------------PQGAIGPHGEKG------- 587
             G+PG PG  G PG QGLPG                     P G  GP GEKG       
Sbjct: 435  PGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCAC 494

Query: 588  ---PQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRG 644
               P G PG PG+PG  G  G  G  G  GTKG+ GP G +GP G PG  G  G  G +G
Sbjct: 495  EPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKG 554

Query: 645  ---------LKGHKGEKGEDGFPGFKGD---------IGVKGDRGEVG-----VPGSRGE 681
                     +KGHKGE+G DG PGF G           G KGD G  G      PG +G 
Sbjct: 555  AKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGF 614

Query: 682  DGPEGPKGRTGPTGDPGP--PGLMGEKGKLGVPGLPG--------------------YPG 719
             GP GP G+ GP G PG   PG  GE+G  GVPG PG                    YPG
Sbjct: 615  PGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPG 674

Query: 720  RQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSG 779
            R GP G  G PG  G  G +GA GLSG  G +G  G  G     GP G  G  G  G  G
Sbjct: 675  RHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGG 734

Query: 780  --GDGPHGPPGERGLPGPQGPNGFPGPK-----GPPGPPGKDGLPGHPGQRGEVGFQGKT 832
              G  P GPPG  G PG  G  G PG       GPPG  G  G+PG  G RG+ G  G  
Sbjct: 735  EKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAE 794

Query: 833  GPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG-- 890
            GP G PG +G +G  G  G  G  G PGPPG   E+G PG  G+ G  G PG PGAPG  
Sbjct: 795  GPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGK 854

Query: 891  -------KDGPAGLRGFPGERGLPGTAGGPGLKGNEGP------SGPPGPAGS------- 930
                     GPAG++G PG  G PG  G PGL G  GP       GPPGP G        
Sbjct: 855  GQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFP 914

Query: 931  --PGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPV---GLP 985
              PGERG  G+ G  G  G PG +G  G  G++G+ G KG IGP G +G    +   G P
Sbjct: 915  GFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTP 974

Query: 986  GPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPG----PPGPIGPVGQPGAAGADGE 1041
            G  GPPG  G  G++G+ G PG +G +G  G +GPPG     PG  G  G PG  G  G 
Sbjct: 975  GEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGS 1034

Query: 1042 PGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGD-VGPMGPPGPPGPRG 1100
             G RG  G  G  GD+G  G  GPPG  G+ G  GP G KG+     GP GP G PG  G
Sbjct: 1035 TGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPG 1094

Query: 1101 PAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGE----- 1155
              G  GA G QG PG  G  G PG  G PG SG PG  G+ G+ G RG+ GE G+     
Sbjct: 1095 CPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRG 1154

Query: 1156 -SGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG--EGGPRGQDGAKGDRGEDGE 1212
              G PG PGPPG KGP+G  G  G  G  G  G  G  G  + GP G  G  G +GE G+
Sbjct: 1155 LQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGD 1214

Query: 1213 PGQPG--SPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPA 1270
            PG PG   PGP G+ GPPGP G  GP G  G+ GR     A  D    G PG  GP GP 
Sbjct: 1215 PGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGR-----APKDIPDPGPPGDQGPPGPD 1269

Query: 1271 GPAGKPGPDGLRGLPGSVGQ-QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGL 1329
            GP G PGP GL   PGSV   +G PG  G  GPPGP GPPG PG +G  G  G+ G  G 
Sbjct: 1270 GPRGAPGPPGL---PGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGP 1326

Query: 1330 IGLIGP---------------PGEQGEKGDRGLPGPQGSPGQ------------------ 1356
            +G  GP               PG  G KG  GLPGP+G PG                   
Sbjct: 1327 VGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPG 1386

Query: 1357 ----KGEMGIPGASGPIGPG--GPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGP 1410
                +G MG+PG  GP GPG  G PGL G  G  G  G+ GP G KG+ G  G PG PGP
Sbjct: 1387 MRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGP 1446

Query: 1411 PGEVIQPLP 1419
            PG +  P P
Sbjct: 1447 PGPIGDPGP 1455



 Score =  858 bits (2216), Expect = 0.0
 Identities = 541/1278 (42%), Positives = 625/1278 (48%), Gaps = 213/1278 (16%)

Query: 313  GPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGS 372
            GPPGP GP G IGP G    PGP+G  GE+G      + G  G PG  G           
Sbjct: 65   GPPGPPGPQGPIGPLGA---PGPIGLSGEKG------MRGDRGPPGAAGDK--------- 106

Query: 373  GGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGP 432
              GDKGP           I         GPPGP G  G  G  G  G PG  G  G LGP
Sbjct: 107  --GDKGPTGVPGFPGLDGIPGHP-----GPPGPRGKPGMSGHNGSRGDPGFPGGRGALGP 159

Query: 433  QGPRGPQGLTGPPGKA--------GRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEK 484
             GP G  G  G  G +        G +G  G  G  G+PG  G  G  G  G PG PG  
Sbjct: 160  GGPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLV 219

Query: 485  GHRGDTGAQGLPGPPGED--GERGDDGEIGPRGLPGES------------GPRGLLGPKG 530
            G  G  G  GL G PG    G+ GD GE+G +G PG +            G +G+ G  G
Sbjct: 220  GPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPG 279

Query: 531  PPGIPGPPG-----------VRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGA 579
              G+PGPPG            +G+ G  GP+G  G  G PG PG +G  G  G PG  G 
Sbjct: 280  MVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGL 339

Query: 580  IGPHGEKGPQGKPGLPGMPGSD-----GPPGHPGKEGPPGTKGNQGPSGPQGPLGYPG-- 632
            IGP G+ G +G PG PG+  +      GPPG PG  G  G  G+ GP GP G LG PG  
Sbjct: 340  IGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEA 399

Query: 633  ------PRGVKGVDGIRGLKGHKGEKGED----GFPGFKGDIGVKGDRGEVGVPGSR--- 679
                  P G +G  G+ GL G  G  G      G PG  G  G+ G  G  G+PGS    
Sbjct: 400  CAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIY 459

Query: 680  ---GEDGPEGPKGRTGPTGDPGPPGLMG-------EKGKLGVPGLPGYPGRQGPKGSLGF 729
               G  GP+G KG+ GP G  GP G  G       E G +G PG PG PGRQG KG LG 
Sbjct: 460  CSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGL 519

Query: 730  PGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE 789
            PG+ G  G+ G  G  G  G  G+ G +GP G +G +G    S  KG  G  GP GPPG 
Sbjct: 520  PGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGF 579

Query: 790  RGLPGPQGPNGFPGPKGPPGPPG--KDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAA 847
             G PG  G +G  G KG PGPPG  +D  PG  G  G +G  GK GP GPPG+       
Sbjct: 580  PGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGL------- 632

Query: 848  GETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD-----PGPPGAPGKDGPAGLRGFPG 902
            G  GP GERGHPG PG PG +G  G  G++G         PG  G PG DGP G +GFPG
Sbjct: 633  GFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPG 692

Query: 903  ERGLPGTAGGPGLKGNEGPSGP---PGPAGSPGERGAAGSGGPIG--PPGRPGPQGPPGA 957
             +G PG +G  G KG  G  G    PGP G  G+ G  G GG  G  P G PGP G PG 
Sbjct: 693  PQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGV 752

Query: 958  AGEKGVPGEK--GPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNK 1015
             G+KG+PG+   G +GP G+ G+ G  G+ GP G PG  G +G  G  G  G KG KG +
Sbjct: 753  NGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGRE 812

Query: 1016 GEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLP 1075
            G  G PG PGP G   + GA G  G+PG  G  G  GA G +G  G  GPPGP G++GLP
Sbjct: 813  GHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLP 872

Query: 1076 GPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSP 1135
            G  G  G  G   P G PG PGP G  G  G  GP+GP G  G  G PGE+G+PG  G P
Sbjct: 873  GLPGRPGAHG---PPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCP 929

Query: 1136 GIQGEPGVKG------PRGERGEKG---------------ESGQPGEPGPPGPKGPTGDD 1174
            G +GEPG KG       RG RG KG               + G PGEPGPPG  G  G+ 
Sbjct: 930  GAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGER 989

Query: 1175 GPKGNP------------GPVGF-------------PGDPGPPGEGGPRGQDGAKGDRGE 1209
            G KG P            GP GF             PG PGPPG  G RG  G  G  G+
Sbjct: 990  GDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGD 1049

Query: 1210 DGEPGQPGSPG----------------PTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKG 1253
             GEPG PG PG                P    GPPGP G+ G  G PG  G  G +G  G
Sbjct: 1050 QGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPG 1109

Query: 1254 DPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGL-- 1311
              G  G+PG+ GP G +GP G PG  G+ GL G  G+ G PG  G  G PG  GPPG+  
Sbjct: 1110 IQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKG 1169

Query: 1312 ----PGLRGDAGAKGEKGHPGLIGL--IGPPGE------QGEKGDRGLPG--PQGSPGQK 1357
                PGL G  G KG+KG  G  GL  +GPPG       +GE+GD G PG  P G  G+K
Sbjct: 1170 PSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKK 1229

Query: 1358 GEMGIPGASGPIGPG-------------GPPGLPGPAGPKGAKGATGP----------GG 1394
            G  G PG+SGP GP              GPPG  GP GP G +GA GP           G
Sbjct: 1230 GPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRG 1289

Query: 1395 PKGEKGVQGPPGHPGPPG 1412
              G+ G+ GPPG PGPPG
Sbjct: 1290 EPGDCGLPGPPGPPGPPG 1307



 Score =  857 bits (2215), Expect = 0.0
 Identities = 542/1281 (42%), Positives = 633/1281 (49%), Gaps = 197/1281 (15%)

Query: 336  VGDPGERGPPGRAGLPGSD---GAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAIL 392
            V + G RGPPG  G  G     GAPGP G S           G+KG              
Sbjct: 58   VPEKGSRGPPGPPGPQGPIGPLGAPGPIGLS-----------GEKG-------------- 92

Query: 393  QQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLT------GPPG 446
                   RGPPG  G  G  GP G PG PGL G  G  GP GPRG  G++      G PG
Sbjct: 93   ---MRGDRGPPGAAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPG 149

Query: 447  KAGRRGRAGADGARGMPGD--------------PGVKGDRGFDGLPGLPGEKGHRGDTGA 492
              G RG  G  G  G PG+               G++GDRG  GLPGLPG  G  G  G 
Sbjct: 150  FPGGRGALGPGGPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGP 209

Query: 493  QGLP------GPPGE--------------DGERGDDGEIGPRGLPGES------------ 520
             G P      GPPG+               G+ GD GE+G +G PG +            
Sbjct: 210  TGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYK 269

Query: 521  GPRGLLGPKGPPGIPGPP-----------GVRGMDGPQGPKGSLGPQGEPGPPGQQGTPG 569
            G +G+ G  G  G+PGPP           G +G+ G  GP+G  G  G PG PG +G  G
Sbjct: 270  GEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELG 329

Query: 570  TQGLPGPQGAIGPHGEKGPQGKPGLPGMPGS-----DGPPGHPGKEGPPGTKGNQGPSGP 624
              G PG  G IGP G+ G +G PG PG+  +      GPPG PG  G  G  G+ GP GP
Sbjct: 330  LVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGP 389

Query: 625  QGPLGYP--------GPRGVKGVDGIRGLKGHKGEKGE----DGFPGFKGDIGVKGDRGE 672
             G LG P        GP G +G  G+ GL G  G  G      G PG  G  G+ G  G 
Sbjct: 390  PGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGL 449

Query: 673  VGVPGSR------GEDGPEGPKGRTGPTGDPGPPGLMG-------EKGKLGVPGLPGYPG 719
             G+PGS       G  GP+G KG+ GP G  GP G  G       E G +G PG PG PG
Sbjct: 450  QGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPG 509

Query: 720  RQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSG 779
            RQG KG LG PG+ G  G+ G  G  G  G  G+ G +GP G +G +G    S  KG  G
Sbjct: 510  RQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKG 569

Query: 780  GDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPG--KDGLPGHPGQRGEVGFQGKTGPPGP 837
              GP GPPG  G PG  G +G  G KG PGPPG  +D  PG  G  G +G  GK GP GP
Sbjct: 570  ERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGP 629

Query: 838  PGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD-----PGPPGAPGKD 892
            PG+       G  GP GERGHPG PG PG +G  G  G++G         PG  G PG D
Sbjct: 630  PGL-------GFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFD 682

Query: 893  GPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP---PGPAGSPGERGAAGSGGPIG--PPG 947
            GP G +GFPG +G PG +G  G KG  G  G    PGP G  G+ G  G GG  G  P G
Sbjct: 683  GPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVG 742

Query: 948  RPGPQGPPGAAGEKGVPGEK--GPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGD 1005
             PGP G PG  G+KG+PG+   G +GP G+ G+ G  G+ GP G PG  G +G  G  G 
Sbjct: 743  PPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGF 802

Query: 1006 PGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGP 1065
             G KG KG +G  G PG PGP G   + GA G  G+PG  G  G  GA G +G  G  GP
Sbjct: 803  LGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGP 862

Query: 1066 PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGE 1125
            PGP G++GLPG  G  G     GP G PG PGP G  G  G  GP+GP G  G  G PGE
Sbjct: 863  PGPAGMKGLPGLPGRPGAH---GPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGE 919

Query: 1126 KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGF 1185
            +G+PG  G PG +GEPG KG  G  G++G  G  G  GPPG +G       KG PG  G 
Sbjct: 920  RGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGP 979

Query: 1186 PGDPGPPGEGGPRGQDGAKGDRGED----------GEPGQPGSPGPTGENGPPGPLGKRG 1235
            PGD G PGE G +G  G +G RGE           GEPG+ G PGP G  GPPG  G RG
Sbjct: 980  PGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRG 1039

Query: 1236 PAGSPGSEGRQGGKGAKGDPGAIGAPGKTGP----------VGPAGPAGKP--------- 1276
              G PG  G QG  G+ G PG  G  G  GP           GP GP G+P         
Sbjct: 1040 FIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHF 1099

Query: 1277 ---GPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLI 1333
               G  GL G+ G  G  GRPG  G +GPPG  G  G+PGLRG  G  G+ G  GL G  
Sbjct: 1100 GASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDP 1159

Query: 1334 GPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASG--PIGPGGPPGLPGPAGPKGAKGATG 1391
            G PG  G KG  G PG  G  G KG+ G  GASG   +GP GP G+PG  G +G  G+ G
Sbjct: 1160 GIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPG 1219

Query: 1392 --PGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSV-DGSRLMQEDEAIPTG--G 1446
              P GP+G+KG  GPPG  GPPG      P     +  + + D      +    P G  G
Sbjct: 1220 ISPPGPRGKKGPPGPPGSSGPPG------PAGATGRAPKDIPDPGPPGDQGPPGPDGPRG 1273

Query: 1447 APGSPGGLEEIFGSLDSLREE 1467
            APG PG    + GS+D LR E
Sbjct: 1274 APGPPG----LPGSVDLLRGE 1290



 Score =  815 bits (2106), Expect = 0.0
 Identities = 518/1214 (42%), Positives = 607/1214 (50%), Gaps = 194/1214 (15%)

Query: 296  KGEKGEPAVLEPGML-VEGPPGPEGPAGL--IGPPGIQGNPGPVGDPGERGPPGRAGLPG 352
            KGEKG   +  PGM+ + GPPG +G +G+   G  GI G PGP GDPG  G PG  GL G
Sbjct: 269  KGEKGIKGI--PGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKG 326

Query: 353  SDGAPGPPGT-SLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGR 411
              G  G PG   L+ P       G  GP           +L    L L+GPPG  G+ GR
Sbjct: 327  ELGLVGDPGLFGLIGPKGDPGNRGHPGP---------PGVLVTPPLPLKGPPGDPGFPGR 377

Query: 412  ---PGPLGQPGSPGLKGESGD-----LGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMP 463
                G +G PG PGL G  G+     +GP GP+G  GL G PG+AG  GR   D A G P
Sbjct: 378  YGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRP--DSAPGKP 435

Query: 464  GDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPR 523
            G PG  G      LPG PG +G  G +      G PG  G +G  G  G RG  GE G  
Sbjct: 436  GKPGSPG------LPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNE 489

Query: 524  GLL----GPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGA 579
            GL     GP GPPG PG PG +G  G  G  G LG +G+PGPPG +G PG   LPG  GA
Sbjct: 490  GLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPG---LPGKHGA 546

Query: 580  IGP------------------HGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPG------- 614
             GP                   GE+GP G PG PG PGS G  GH G++G PG       
Sbjct: 547  SGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHED 606

Query: 615  -TKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEV 673
             T G +G  GP GP G  GP G  G+ G  G  G +G  G  G PG +G  G+KG +G+ 
Sbjct: 607  ATPGGKGFPGPLGPPGKAGPVGPPGL-GFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDT 665

Query: 674  --------GVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG---LPGYPGRQG 722
                    G  G  G DGP GPKG  GP G PG  G  G KG+ G PG   +PG PG +G
Sbjct: 666  ISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRG 725

Query: 723  PKGSLGF--------------PGFPGASGEKGARG--LSGKSGPRGERGPTGPRGQRGPR 766
              G  GF              PG PG +G+KG  G    G  GP G+RG +G  G +GPR
Sbjct: 726  DMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPR 785

Query: 767  GATGKSGAKGTSGGDG------PHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHP 820
            G  G  GA+G +G  G      P G  G  G PG  GP G    +G PG PG+ GLPG+P
Sbjct: 786  GDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYP 845

Query: 821  GQRGEVGFQGK---TGPPGP------------PGVVGPQGAAGETGPMGERGHPGPPGPP 865
            G  G  G +G+    GPPGP            PG  GP G  G  GP G+ G PGPPGP 
Sbjct: 846  GSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPK 905

Query: 866  GEQGLPGTAGKEGTKGDPGP---PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPS 922
            G +GLPG  G  G +G PG    PGA G+ G  G+ G PG+RGL G  G  G  G+EG  
Sbjct: 906  GPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEM 965

Query: 923  ------------GPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPG----AAGEKGVPGE 966
                        GPPG  G PGERG  G+ G  G  G PG  GPPG      GEKG PG 
Sbjct: 966  AIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGP 1025

Query: 967  KGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE----HGPPG 1022
             GP GP G  G++G +G PG  G  G  G  G  G  G  G +G KGNKG+     GPPG
Sbjct: 1026 PGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPG 1085

Query: 1023 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKG 1082
            P G  G  G PG  GA GE G  G QG  G+ G  G  G +GPPG  G  G+PG  G+ G
Sbjct: 1086 PKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPG 1145

Query: 1083 ETGDVGPMGP------PGPPGPRGPAGPNGADGPQGPPG--------GVGNLGPPGE--- 1125
            E GD GP G       PGPPG +GP+G  G +G  G  G        G+ ++GPPG    
Sbjct: 1146 EMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGI 1205

Query: 1126 ---KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPG-------------EPGPPGPKG 1169
               KGE G+ GSPGI   PG +G +G  G  G SG PG             +PGPPG +G
Sbjct: 1206 PGLKGERGDPGSPGIS-PPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQG 1264

Query: 1170 PTGDDGPKGNPGPVGFPGD----------------PGPPGEGGPRGQDGAKGDRGEDGEP 1213
            P G DGP+G PGP G PG                 PGPPG  GP G  G  G  G+DG+ 
Sbjct: 1265 PPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQK 1324

Query: 1214 GQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIG-------APGKTGP 1266
            G  G PGP G +G PGP G++G  G PG +G  G  G +G+PG           PG  G 
Sbjct: 1325 GPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGA 1384

Query: 1267 VGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGH 1326
             G  GP G  G  G+RG P   G +G PG  G+ G  G  G PG PG +GD G  G  G 
Sbjct: 1385 PGMRGPEGAMGLPGMRG-PSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGG 1443

Query: 1327 PGLIGLIGPPGEQG 1340
            PG  G IG PG +G
Sbjct: 1444 PGPPGPIGDPGPKG 1457



 Score =  720 bits (1858), Expect = 0.0
 Identities = 454/1082 (41%), Positives = 522/1082 (48%), Gaps = 187/1082 (17%)

Query: 291  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPG-PVGDPGERGPPGRAG 349
            GP GL G  GE      GM+  GPPGP+G  GL G PG  G PG P   PG+ G PG  G
Sbjct: 388  GPPGLLGRPGEACA---GMI--GPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPG 442

Query: 350  LPGSDGAPGPPGTSLM-----------LPFRFGSGGGDKGPVVAAQEAQAQAILQQARLA 398
            LPG+ G  G PG+S++           +  + G  GG +GP    +  +    L      
Sbjct: 443  LPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGG-RGP----KGEKGNEGLCACEPG 497

Query: 399  LRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADG 458
              GPPGP G  GR G  G  G PG  G  GD GP G  GP GL G  G +G  G  GA G
Sbjct: 498  PMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKG 557

Query: 459  ARGMPGDPGVKGDRGFDGLPGLPGEKGHRG---DTGAQGLPGPPG--EDGERGDDGEIGP 513
               +    G KG+RG DG PG PG+ G  G     G +G PGPPG  ED   G  G  GP
Sbjct: 558  DMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGP 617

Query: 514  RGLPGESGP--------RGLLGPKGPPGIPGPPGVRGMDGPQGPKG-----SLGPQGEPG 560
             G PG++GP         G  G +G PG+PG PGVRG DG +G KG     ++   G  G
Sbjct: 618  LGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHG 677

Query: 561  PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQG 620
            PPG  G PG +G PGPQGA G  G  G +G+PG PG     GPPG  G  G PG  G +G
Sbjct: 678  PPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKG 737

Query: 621  --PSGPQGP--------------------LGYPGPRGVKGVDGIRG-------------- 644
              P GP GP                    LG PG RG+ GV GI+G              
Sbjct: 738  SSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPA 797

Query: 645  -------LKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRG----------------- 680
                   LKG KG +G  GFPG  G  G   +RG  G+PG  G                 
Sbjct: 798  GIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQP 857

Query: 681  -EDGPEGPKGRTGPTGDPG------PPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFP 733
             + GP GP G  G  G PG      PPGL G  G  G  GLPG PG +GP+G  GFPGFP
Sbjct: 858  GDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFP 917

Query: 734  GASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGG---------DGPH 784
            G  G+ GA G  G  G  GE+G +G  G RG RGA G  G  G  G           G  
Sbjct: 918  GERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEP 977

Query: 785  GPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPG-HPGQRGEVGFQGKTGPPGPPGVVGP 843
            GPPG+ G PG +G  G PG +G  G PG+ G PG H G+ GE G  G  GPPGPPG  G 
Sbjct: 978  GPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGL 1037

Query: 844  QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP-------GPPGAPGKDGPAG 896
            +G  G  G  G++G PG PGPPG  G+ G  G +G KGDP       GP G PG  G  G
Sbjct: 1038 RGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPG 1097

Query: 897  LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPG 956
              G  GE+GLPG  G  G  G  GP G  GP G PG+ G  G  G  G  G PGP+G  G
Sbjct: 1098 HFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQG 1157

Query: 957  AAGEKGVPGEKGPIGPTGRDGVQG--------------PVGLPGPAGPPGVAGEDGDKGE 1002
              G  G PG KGP G  G +G+ G               VG PGP G PG+ GE GD G 
Sbjct: 1158 DPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGS 1217

Query: 1003 VG--DPGQKGTKGNKGEHGPPGPPGPIGPVGQ-------PGAAGADGEPGARGPQGHFGA 1053
             G   PG +G KG  G  G  GPPGP G  G+       PG  G  G PG  GP+G  G 
Sbjct: 1218 PGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGP 1277

Query: 1054 ----------KGDEGTRGFNGPPGPIGLQGLPGPSGEKG---ETGDVGPMGPPGPPGPRG 1100
                      +G+ G  G  GPPGP G  G PG  G  G   + G  GP+G PGP GP G
Sbjct: 1278 PGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHG 1337

Query: 1101 PAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGS-------PGIQGEPGVKGPRGERG-- 1151
              GP G  G  GPPG  G  G PG +GEPG           PG+ G PG++GP G  G  
Sbjct: 1338 FPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLP 1397

Query: 1152 ------------------EKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG 1193
                               +G  G PG PGPPG KG TG+DG  G PGP G  GDPGP G
Sbjct: 1398 GMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKG 1457

Query: 1194 EG 1195
             G
Sbjct: 1458 FG 1459



 Score =  638 bits (1645), Expect = 0.0
 Identities = 396/915 (43%), Positives = 454/915 (49%), Gaps = 129/915 (14%)

Query: 284  PLEEAAHGPRGLKGEKGEPA-------VLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPV 336
            P +  +HG  G  GEKG+P            G    GP GP G AG +GPPG+ G PGP 
Sbjct: 580  PGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGL-GFPGP- 637

Query: 337  GDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQAR 396
              PGERG PG   +PG  G  GP G             G KG  ++              
Sbjct: 638  --PGERGHPG---VPGHPGVRGPDGLK-----------GQKGDTISCN------------ 669

Query: 397  LALRGPPGPMGYTGRPGPLGQPG---SPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGR 453
            +   G  GP G+ G PGP G PG   +PGL G  G  G  G  G   + GPPG  G  G 
Sbjct: 670  VTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGD 729

Query: 454  AGADGARGMP--GDPGVKGDRGFDGLPGLPGEK--GHRGDTGAQGLPGPPGEDGERGDDG 509
             G  G +G    G PG  G  G +G  G+PG+   GH G  G +GL G PG  G RGD G
Sbjct: 730  PGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPG 789

Query: 510  EIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPG 569
              G  G  G  G  GL GPKG  G  G PGV G  G    +G+ G  G+PG PG  G+PG
Sbjct: 790  CPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPG 849

Query: 570  TQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPL- 628
              G  G  G +GP G  G +G PGLPG PG+ GPPG PG  GP G  G  GP GP+GP  
Sbjct: 850  APGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRG 909

Query: 629  -----GYPGPRGVKGVDGIRGLKGHKGEKGEDGFP------GFKGDIGVKGDRGEV---- 673
                 G+PG RG  G +G  G KG  GEKG  G P      G KG IG  GD GE+    
Sbjct: 910  LPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIIS 969

Query: 674  --------------GVPGSRGEDGPEGPKGRTGPTGDPGPPGL----MGEKGKLGVPGLP 715
                          G PG RG+ G  G +GR G  G  GPPG      GEKG+ G PG P
Sbjct: 970  QKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPP 1029

Query: 716  GYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPR-GATGKSGA 774
            G PG  G +G +GFPG PG  GE G+ G  G SG  G RGP G +G      G  G  G 
Sbjct: 1030 GPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGE 1089

Query: 775  KGTSGGDGPHGPPGERGLPGPQGPNGF------PGPKGPPGPPGKDGLPGHPGQRGEV-- 826
             G+ G  G  G  GE+GLPG QGP G       PG  GPPG PG  G+PG  GQ GE+  
Sbjct: 1090 PGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGD 1149

Query: 827  ----GFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP--------GPPGEQGLPGTA 874
                G QG  G PGPPG+ GP G+ G  G  G +G  G          GPPG  G+PG  
Sbjct: 1150 PGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLK 1209

Query: 875  GKEGTKGDPG--PPGAPGKDGPAGLRGFPGERGLPGTAGG----------PGLKGNEGPS 922
            G+ G  G PG  PPG  GK GP G    PG  G PG AG           PG  G++GP 
Sbjct: 1210 GERGDPGSPGISPPGPRGKKGPPGP---PGSSGPPGPAGATGRAPKDIPDPGPPGDQGPP 1266

Query: 923  GPPGPAGSPGERGAAGSGGPI-GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGP 981
            GP GP G+PG  G  GS   + G PG  G  GPPG  G  G PG KG  G  G+DG +GP
Sbjct: 1267 GPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGP 1326

Query: 982  VGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPI----------GPVG 1031
            VG PGP GP G  G  G+KG  G PG+KG  G  G  G PGPP  +          G  G
Sbjct: 1327 VGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPG 1386

Query: 1032 QPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMG 1091
              G  GA G PG RGP G     G +G  G +G  G  G+ G PGP G KG+TG+ G  G
Sbjct: 1387 MRGPEGAMGLPGMRGPSG----PGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPG 1442

Query: 1092 PPGPPGPRGPAGPNG 1106
             PGPPGP G  GP G
Sbjct: 1443 GPGPPGPIGDPGPKG 1457



 Score =  352 bits (902), Expect = 2e-96
 Identities = 239/601 (39%), Positives = 273/601 (45%), Gaps = 114/601 (18%)

Query: 291  GPRGLKGEKGEP----AVLEPGMLVEGPPGPEGPAGLIGPPGIQGN---PGPVGDPGERG 343
            GP G+KG  G P    A   PG+   G PGP G  GL GPPG +G    PG  G PGERG
Sbjct: 864  GPAGMKGLPGLPGRPGAHGPPGL--PGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERG 921

Query: 344  PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPP 403
             PG  G PG+ G PG  G S  LP   G  G          E +   I Q+      GPP
Sbjct: 922  KPGAEGCPGAKGEPGEKGMS-GLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPP 980

Query: 404  GPMGYTGRPGPLGQPGSPGLKGESGDLGP----------QGPRGPQGLTGPPGKAGRRGR 453
            G  G+ G  G  G PG  G +GE G  GP          +G  GP G  GPPG  G RG 
Sbjct: 981  GDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGF 1040

Query: 454  AGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQ-GLPGPPGE----------- 501
             G  G  G  G+PG  G  GF G+ G  G KG++GD  +  G PGP GE           
Sbjct: 1041 IGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFG 1100

Query: 502  -DGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG 560
              GE+G  G  GPRG PG  GP G  GP G PG  G PG+RG  G  G  G  G QG+PG
Sbjct: 1101 ASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPG 1160

Query: 561  PPG---------------------QQGTPGTQGL-----PGPQGAIGPHGEKGPQGKPGL 594
             PG                     Q+GT G  GL     PGP G  G  GE+G  G PG+
Sbjct: 1161 IPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGI 1220

Query: 595  --PGMPGSDGPPGHPGKEGPPGTKG----------------NQGPSGPQGPLGYPGPRGV 636
              PG  G  GPPG PG  GPPG  G                +QGP GP GP G PGP G+
Sbjct: 1221 SPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGL 1280

Query: 637  KG-VDGIRGLKG------------------HKGEKGEDGFPGFKGDIGVKGDRGEVGVPG 677
             G VD +RG  G                  +KG  G DG  G KG +G  G +G  G PG
Sbjct: 1281 PGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPG 1340

Query: 678  SRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLG----VPGLPGYPGRQGPKGSLGFPGF- 732
              GE G  GP GR GPTG PGP G  G    +     +PGLPG PG +GP+G++G PG  
Sbjct: 1341 PPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMR 1400

Query: 733  -------------PGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSG 779
                          G  G  G  G  G  G +G+ G  G  G  GP G  G  G KG   
Sbjct: 1401 GPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGFGP 1460

Query: 780  G 780
            G
Sbjct: 1461 G 1461



 Score =  140 bits (352), Expect = 1e-32
 Identities = 96/256 (37%), Positives = 112/256 (43%), Gaps = 67/256 (26%)

Query: 283  PPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDP--- 339
            PP ++   GP G +G  G P +     L+ G PG  G  G  GPPG  G PG  G P   
Sbjct: 1259 PPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCD 1318

Query: 340  ---GERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQAR 396
               G++GP G  G  G  G PGPP              G+KG                  
Sbjct: 1319 GKDGQKGPVGFPGPQGPHGFPGPP--------------GEKG------------------ 1346

Query: 397  LALRGPPGPMGYTGRPGPLGQPGS----------PGLKGESGDLGPQGPRGPQGLTGPPG 446
              L GPPG  G TG PGP G+PG           PGL G  G  GP+G  G  G+ GP G
Sbjct: 1347 --LPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSG 1404

Query: 447  KAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERG 506
                          G  G+PG+ G RG DG+PG PG  G +GDTG  G PG PG  G  G
Sbjct: 1405 P-------------GCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIG 1451

Query: 507  DDGEIGPRGL-PGESG 521
            D    GP+G  PG  G
Sbjct: 1452 DP---GPKGFGPGYLG 1464


>gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]
          Length = 1714

 Score =  871 bits (2251), Expect = 0.0
 Identities = 525/1286 (40%), Positives = 647/1286 (50%), Gaps = 117/1286 (9%)

Query: 423  LKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGL-PGLP 481
            L+G  GD GP GP GP G+ GP GK G RG  G  G  G+PG PG KG +G  G  PG P
Sbjct: 487  LRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQP 546

Query: 482  GEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVR 541
               G +GD G  GL GPPG  G++G  G  G  GLPGE G  G  G  G PG PG  G+ 
Sbjct: 547  -VPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLA 605

Query: 542  GMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG---------PQGAIGPHGEKGPQGKP 592
            G +G  GPKG+ G  G PG  GQ G  G +G+PG          QG  G  G++GP G  
Sbjct: 606  GPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLD 665

Query: 593  GLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEK 652
            G PG+ G  GPPG PG  G  G  G  GP+G  GP+G  G +G+ G+ G +G +G  GE 
Sbjct: 666  GSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGEL 725

Query: 653  GEDGFPGFKGDIGV---------KGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLM 703
            GE G+PG KG +G+          G  G+ G PG +G  GP GP+G  G  G PG  G  
Sbjct: 726  GEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPE 785

Query: 704  GEKGKLG---VPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPR 760
            G KG LG    PG PG  G QG +G +G  G  G  G+ G +G +G+ GP G +G  G +
Sbjct: 786  GPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQ 845

Query: 761  GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPN------GFPGPKGPPGPPGKD 814
            G  G  G TG  G  G  G  G  G  GERG PGP GP       G+PGP G PGP G  
Sbjct: 846  GNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPL 905

Query: 815  GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTA 874
            GLPGH G R         GPPG  G  G +G+ G  G +GE+G  G  G  G+QG  G  
Sbjct: 906  GLPGHVGAR---------GPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPH 956

Query: 875  GKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGER 934
            G  G  G+PG  G  GK G  GL G  G+RGLPG    PGL+G +G  GPPG  G  G  
Sbjct: 957  GLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGE---PGLRGLQGDVGPPGEMGMEGPP 1013

Query: 935  GAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA 994
            G  G  G  G PG  G  G  G+ G  G PG +G  G  G +G+QG  GL G  G  G+ 
Sbjct: 1014 GTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLP 1073

Query: 995  GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK 1054
            GEDG+KGE+G PG  G  G  G+ G PGP G +G  GQ G  G  G+ G  GP G  G++
Sbjct: 1074 GEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSR 1133

Query: 1055 GDEGTRGFNGPP------GPIGLQGLPGPSGEKGETGDVGPMGPPGP---PGPRGPAGPN 1105
            G  G  G +GP       G +G  GL GP GE G  G  G  G PGP   PGP+G  G  
Sbjct: 1134 GPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYP 1193

Query: 1106 GAD----GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGE 1161
            G D    GP GP G  G +G  GE+GEPG  G  G  G PG++G  G++G  GE G  GE
Sbjct: 1194 GEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGE 1253

Query: 1162 PGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGP 1221
             G  G +G  G+ G KG PGP G PG PG  G  GP+   G +G  G DG  G PG  GP
Sbjct: 1254 QGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPK---GIQGYHGADGISGNPGKIGP 1310

Query: 1222 TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL 1281
             G+ G P   G RG  G  G  G  G  G KG  G  G+PG  GP G  G  G+PG  G 
Sbjct: 1311 PGKQGLP---GIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGK 1367

Query: 1282 RGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGE 1341
            RG  G+ G QG  G  G  G PG  G  GL G +G  G KG +G  G++G+ GP G  G 
Sbjct: 1368 RGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGH 1427

Query: 1342 KGD------RGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGP 1395
            +G+       G+ GP G  G +GE G  G +GP GP G PG P                 
Sbjct: 1428 RGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPP----------------- 1470

Query: 1396 KGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLE 1455
                   GPPG PGP  ++     IQ   ++  ++        +  +            E
Sbjct: 1471 -------GPPGAPGPRKQMDINAAIQALIESNTALQMESYQNTEVTLIDHS--------E 1515

Query: 1456 EIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRV 1515
            EIF +L+ L   +  ++ P GT+D+PAR C+DL  C  ++ DG+YW+DPN GC  DA  V
Sbjct: 1516 EIFKTLNYLSNLLHSIKNPLGTRDNPARICKDLLNCEQKVSDGKYWIDPNLGCPSDAIEV 1575

Query: 1516 FCNFTAGGETCVTPRDDVTQFSYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPCSGAAR- 1574
            FCNF+AGG+TC+ P   VT+  +       VG VQ+ FL LLS  A   ++  C    R 
Sbjct: 1576 FCNFSAGGQTCLPP-VSVTKLEF------GVGKVQMNFLHLLSSEATHIITIHCLNTPRW 1628

Query: 1575 --------DGPLRLRGANEDELSPETSPYVKEFRDGCQTQQG---RTVLEVRTPVLEQLP 1623
                      P+  +G N       T    K   D C+ Q G   +      T    QLP
Sbjct: 1629 TSTQTSGPGLPIGFKGWNGQIFKVNTLLEPKVLSDDCKIQDGSWHKATFLFHTQEPNQLP 1688

Query: 1624 VLDASFSDLGAPPRRGGVLLGPVCFM 1649
            V++          R+  +    VCF+
Sbjct: 1689 VIEVQKLPHLKTERKYYIDSSSVCFL 1714



 Score =  763 bits (1970), Expect = 0.0
 Identities = 462/1043 (44%), Positives = 525/1043 (50%), Gaps = 72/1043 (6%)

Query: 295  LKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSD 354
            L+G KG+           GPPGP GPAG+ GP    G  GP G PG  G PG  GLPG  
Sbjct: 487  LRGPKGDT----------GPPGPPGPAGIPGP---SGKRGPRGIPGPHGNPGLPGLPGPK 533

Query: 355  GAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGP 414
            G  G PG S   P     G      ++     Q    L+     L G PG  G  G  G 
Sbjct: 534  GPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLK-GHPGLPGLPGEQGIPGFAGN 592

Query: 415  LGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGF 474
            +G PG PG +G +G  G  GP+G QG  G PG+A   G+ G +G RG+   PG++G +GF
Sbjct: 593  IGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEA---GQLGPEGERGI---PGIRGKKGF 646

Query: 475  DGLPGLPGEKGHRGDTGAQGLP------GPPGEDGERGDDGEIGPRGLPGESGPRGLLGP 528
             G  G PG+ G RG  G  G P      GPPG  G RG  G +GP G  G  GP GL G 
Sbjct: 647  KGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGN 706

Query: 529  KGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 588
            KG PGI G  G +G  G  G  G  G +G  G P   G PG +G  GP G  G  G +GP
Sbjct: 707  KGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLP---GPPGMRGKSGPSGQTGDPGLQGP 763

Query: 589  QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGP---QGPLGYPGPRGVKGVDGIRGL 645
             G PG  G PG  G PG  G EGP G  GN+GP GP   +G  G  GP G  G  G RG 
Sbjct: 764  SGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGK 823

Query: 646  KGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGE 705
             G KG  GE G  G KG++G +G+ G++G  G  G  G  G  G  G  G+ G PG +G 
Sbjct: 824  PGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGP 883

Query: 706  KGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGP 765
            +G+ GV G PG PG  GP G LG P      G  GARG  G  GP+G+RG  GP G  G 
Sbjct: 884  QGEKGVMGYPGPPGVPGPIGPLGLP------GHVGARGPPGSQGPKGQRGSRGPDGLLGE 937

Query: 766  RGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGE 825
            +G  G  G KG  G  GPHG  G+ G PG +G  G PG +G PG  G  GLPG PG R  
Sbjct: 938  QGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLR-- 995

Query: 826  VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGP 885
             G QG  GPPG  G+ GP G  GE+G  GE   PG  G  G  G  G  G+ G +G+PG 
Sbjct: 996  -GLQGDVGPPGEMGMEGPPGTEGESGLQGE---PGAKGDVGTAGSVGGTGEPGLRGEPGA 1051

Query: 886  PGAPGKDGPAGLRGFPGERGLP---GTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGP 942
            PG  G  G  GL+G PG RGLP   G  G  GL G  GP G  G  G PG  G  G  G 
Sbjct: 1052 PGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQ 1111

Query: 943  IGPPGRPGPQ---GPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGD 999
             G PG+ G +   GP G  G +G PG+ G  GP G  G +G VG  G  GP G  G  G 
Sbjct: 1112 RGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGY 1171

Query: 1000 KGEVGDPGQKGTKGNKGEHGPP-------GPPGPIGPVGQPGAAGADGEPGARGPQGHFG 1052
            +G  G PG  G  G KGE G P       GPPGP G  G  G  G  GEPGA G +GH G
Sbjct: 1172 RGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVG 1231

Query: 1053 AKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQG 1112
              G  G  G  GPPG  G Q   G  G KGE G  G  G  G PGP G  G  G  G  G
Sbjct: 1232 VPGLRGATGQQGPPGEPGDQ---GEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLG 1288

Query: 1113 PPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTG 1172
            P G  G  G  G  G PG+ G PG QG PG+      RG  G +G  G PGPPG KG +G
Sbjct: 1289 PKGIQGYHGADGISGNPGKIGPPGKQGLPGI------RGGPGRTGLAGAPGPPGVKGSSG 1342

Query: 1173 DDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLG 1232
              G  G  GP G  G PG PG  G RG  GA+GD+G  G+PG  G PG  G  G  G  G
Sbjct: 1343 LPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQG 1402

Query: 1233 KRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQG 1292
              GP G  G  G  G  G KG  G  G  G  G  G  GP G+ GP G +G  G  G Q 
Sbjct: 1403 FPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQ- 1461

Query: 1293 RPGATGQAGPPGPVGPPGLPGLR 1315
                 G  G PGP GPPG PG R
Sbjct: 1462 -----GPRGQPGPPGPPGAPGPR 1479



 Score =  714 bits (1844), Expect = 0.0
 Identities = 430/1001 (42%), Positives = 502/1001 (50%), Gaps = 91/1001 (9%)

Query: 284  PLEEAAHGPRGLKGEKGEPAV--------------LEPGMLVEGPPGPEGPAGLIGPPGI 329
            P      GPRG+ G  G P +                PG  V G  G +G +GL+GPPG+
Sbjct: 506  PGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGM 565

Query: 330  QGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--GDKGPVVA----- 382
            QG+ G  G PG  G PG  G+PG  G  G PG     P R G  G  G+ GP  A     
Sbjct: 566  QGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPG----YPGRQGLAGPEGNPGPKGAQGFIG 621

Query: 383  --AQEAQAQAILQQARLALRGPP---------------GPMGYTGRPGPLGQPGSPGLKG 425
               +  Q     ++    +RG                 GP G  G PG +G  G PG  G
Sbjct: 622  SPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPG 681

Query: 426  ESGDLGPQGPRGPQGLTGP---------PGKAGRRGRAGADGARGMPGDPGVKGDRGFDG 476
              G +GP GP GP G+ GP         PG  G +G  G  G  G PG PG KG  G  G
Sbjct: 682  LRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPG 741

Query: 477  LPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPG 536
             PG+ G+ G  G TG  GL GP G  G  G  G+IG  G  G  GP+GLLG +GPPG PG
Sbjct: 742  PPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPG 801

Query: 537  PPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP---GPQGAIGPHGEKGPQGKPG 593
              G +G +GP G  G LGP+G+PG  G  G PG +GL    G QG IG  GE GP G PG
Sbjct: 802  LKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPG 861

Query: 594  LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 653
              GM GS G  G  G  GP       GP G +G +GYPGP GV G  G  GL GH G +G
Sbjct: 862  EVGMTGSIGEKGERGSPGP------LGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARG 915

Query: 654  EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 713
                    G  G KG RG  G  G  GE G +G KG  G  G  GP GL+G+ G  G  G
Sbjct: 916  P------PGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERG 969

Query: 714  LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG 773
              G PG QG  GS G  G P   GE G RGL G  GP GE G  GP G  G  G  G+ G
Sbjct: 970  FQGKPGLQGLPGSTGDRGLP---GEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPG 1026

Query: 774  AK---GTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQG 830
            AK   GT+G  G  G PG RG PG  G  G  G  G  G PG  GLPG  G++GE+G   
Sbjct: 1027 AKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGL-- 1084

Query: 831  KTGPPGPPGVVGPQGAAGET---GPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPG 887
                   PG++GP G +G+T   GP G  G PG  G PG++G  G  G  G  G  GPPG
Sbjct: 1085 -------PGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPG 1137

Query: 888  APGKDGP---AGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGP-- 942
              GK GP    G RG  G  GL G  G PG+ G  G  G PGP+G PG +G  G  G   
Sbjct: 1138 KIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDS 1197

Query: 943  --IGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDK 1000
              +GPPG  G  GP G  GE+G PG +G  G  G  G++G  G  GP G PG  GE G K
Sbjct: 1198 TVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLK 1257

Query: 1001 GEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1060
            GE G  G KG KG  G  G PG PG  G +G  G  G  G  G  G  G  G  G +G  
Sbjct: 1258 GERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLP 1317

Query: 1061 GFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNL 1120
            G  G PG  GL G PGP G KG +G  G  G  GP G +G  G  G  G +G  G  G+ 
Sbjct: 1318 GIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQ 1377

Query: 1121 GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP 1180
            GP G+ G  G+ G  G+QG  G +G  G +G +G++G  G  GP GP G  G+ GP G  
Sbjct: 1378 GPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGRE 1437

Query: 1181 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGP 1221
            G +G  G  GP GE G RG+ G +G RG+ G PG PG+PGP
Sbjct: 1438 GIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGP 1478



 Score =  520 bits (1338), Expect = e-147
 Identities = 326/767 (42%), Positives = 382/767 (49%), Gaps = 80/767 (10%)

Query: 259  QNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPE 318
            Q  +P  Q P+     E     +  P +    GP+GL G +G P    PG+  +G  G E
Sbjct: 754  QTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPG--PPGL--KGTQGEE 809

Query: 319  GPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTS--LMLPFRFGSGG-- 374
            GP G  G  G +G PG  G  GE GP G  G  G  G  G  G +  + LP   G  G  
Sbjct: 810  GPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSI 869

Query: 375  GDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL---G 431
            G+KG                     RG PGP+G  G  G +G PG PG+ G  G L   G
Sbjct: 870  GEKGE--------------------RGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPG 909

Query: 432  PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTG 491
              G RGP G  GP G+ G RG  G  G +G+ G  G KGD+G  G  GL G+ G+ G+ G
Sbjct: 910  HVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERG 969

Query: 492  AQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKG 551
             QG PG  G  G  GD      RGLPGE G RGL G        GPPG  GM+GP G +G
Sbjct: 970  FQGKPGLQGLPGSTGD------RGLPGEPGLRGLQGD------VGPPGEMGMEGPPGTEG 1017

Query: 552  SLGPQGEPGPPGQQGTPGT---QGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPG 608
              G QGEPG  G  GT G+    G PG +G  G  GE+G QGK GL G+PG  G PG  G
Sbjct: 1018 ESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDG 1077

Query: 609  KEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKG 668
            ++G  G  G  GP G  G  G PGP G+ G+ G RG  G KG+KG+ G  G  G  G  G
Sbjct: 1078 EKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPG 1137

Query: 669  DRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLP------GYPGRQ- 721
              G+ G  G+RG  G  G  G  GP G+PG PG  G +G+ G  GLP      GYPG   
Sbjct: 1138 KIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDS 1197

Query: 722  ------------GPKGSLGFPGFPGASGEK------GARGLSGKSGPRGERGPTGPRGQR 763
                        GP G  G  G PGA G K      G RG +G+ GP GE G  G +G +
Sbjct: 1198 TVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLK 1257

Query: 764  GPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGH---P 820
            G RG+ G  G KG  G  G  G PG +GL GP+G  G+ G  G  G PGK G PG    P
Sbjct: 1258 GERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLP 1317

Query: 821  GQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTK 880
            G RG  G  G  G PGPPGV G  G  G  G  G +G  G PG PG QG  G  G +G +
Sbjct: 1318 GIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQ 1377

Query: 881  GDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSG 940
            G  G PG  G+ G  G++G  G +G PG  G  G  G  G SGP GP G  G  G  G  
Sbjct: 1378 GPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGRE 1437

Query: 941  GPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGP 987
            G IGP GR GP+      GEKG  GE GP GP G+ G  GP G PGP
Sbjct: 1438 GIIGPTGRTGPR------GEKGFRGETGPQGPRGQPGPPGPPGAPGP 1478



 Score =  366 bits (940), Expect = e-101
 Identities = 219/511 (42%), Positives = 262/511 (51%), Gaps = 50/511 (9%)

Query: 291  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 350
            G RGL+G+ G P   E GM  EGPPG EG +GL G PG +G+ G  G  G  G PG  G 
Sbjct: 993  GLRGLQGDVGPPG--EMGM--EGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGE 1048

Query: 351  PGSDGAPGPPGTSLMLPFRFGSG----GGDKGPVVAAQEAQAQAILQQARLALRGPPGPM 406
            PG+ G  G  G   +     G G     G+KG              +     + GP G  
Sbjct: 1049 PGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKG--------------EMGLPGIIGPLGRS 1094

Query: 407  GYTGRPGP---LGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMP 463
            G TG PGP   +G PG  G  G+ GD G  GP G  G  GPPGK G+ G  GA G RG  
Sbjct: 1095 GQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAV 1154

Query: 464  GDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI-GPRGLPGESGP 522
            G  G+ G    DG PG+PG +GH+G  G  GLPGP GE G  G+D  + GP G  GE GP
Sbjct: 1155 GHLGLMGP---DGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGP 1211

Query: 523  RGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGP 582
               +G +G  G PG  G +G  G  G +G+ G QG PG PG QG  G +G  G +G  G 
Sbjct: 1212 ---VGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGK 1268

Query: 583  HGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGI 642
             G  GP GKPG+PG+ G  GP G  G  G  G  GN G  GP G  G PG RG  G  G+
Sbjct: 1269 KGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGL 1328

Query: 643  RGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGL 702
             G  G  G KG  G PG  G  G KG++G  G PG +G+ G  G +G  GP GDPG  G 
Sbjct: 1329 AGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQ 1388

Query: 703  MGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSG------------KSGP 750
             GE G  G+ G  G+PG +GP+G  G  G  G  G  G RG +G            ++GP
Sbjct: 1389 PGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGP 1448

Query: 751  RGERG------PTGPRGQRGPRGATGKSGAK 775
            RGE+G      P GPRGQ GP G  G  G +
Sbjct: 1449 RGEKGFRGETGPQGPRGQPGPPGPPGAPGPR 1479



 Score =  200 bits (509), Expect = 8e-51
 Identities = 136/339 (40%), Positives = 162/339 (47%), Gaps = 36/339 (10%)

Query: 242  HRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGE 301
            H+ Q  P   P          P+ +   PGE+  +L     PP      GP G +GE+GE
Sbjct: 1174 HQGQPGPSGLPG---------PKGEKGYPGEDSTVLG----PPGPRGEPGPVGDQGERGE 1220

Query: 302  PAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPG---RAGLPGSDGAPG 358
            P   E      G PG  G  G  GPPG  G+ G  G  GERG  G   + G PG  G PG
Sbjct: 1221 PGA-EGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPG 1279

Query: 359  PPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQP 418
             PG   +L  + G  G      ++    +     +Q    +RG PG  G  G PGP G  
Sbjct: 1280 IPGLQGLLGPK-GIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVK 1338

Query: 419  GSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLP 478
            GS GL G  G    QGP+G QGL G PG  G+RG  GA G +G  GDPG+KG        
Sbjct: 1339 GSSGLPGSPGI---QGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQ------- 1388

Query: 479  GLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPP 538
              PGE G +G TG QG PGP G +G+ G  G  GP+   G  G RG  GP G  GI GP 
Sbjct: 1389 --PGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPK---GPIGHRGNTGPLGREGIIGP- 1442

Query: 539  GVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQ 577
               G  GP+G KG  G  G  GP GQ G PG  G PGP+
Sbjct: 1443 --TGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPR 1479



 Score =  103 bits (256), Expect = 2e-21
 Identities = 73/188 (38%), Positives = 84/188 (44%), Gaps = 48/188 (25%)

Query: 289  AHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQG---------NPGPVGDP 339
            A GP G+KG  G P    PG+      GP+G  GL G PGIQG         + GP GDP
Sbjct: 1331 APGPPGVKGSSGLPG--SPGI-----QGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDP 1383

Query: 340  GERGPPGR---AGLPGSDGAPGPPGTSLMLPFRFGSGG-----GDKGPVVAAQEAQAQAI 391
            G +G PG     GL G  G PGP G         G  G     G KGP+           
Sbjct: 1384 GLKGQPGEYGVQGLTGFQGFPGPKGPE-------GDAGIVGISGPKGPI----------- 1425

Query: 392  LQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRR 451
                    RG  GP+G  G  GP G+ G  G KG  G+ GPQGPRG  G  GPPG  G R
Sbjct: 1426 ------GHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPR 1479

Query: 452  GRAGADGA 459
             +   + A
Sbjct: 1480 KQMDINAA 1487



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 43/178 (24%), Positives = 85/178 (47%), Gaps = 12/178 (6%)

Query: 66  AQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPVRFLYE 125
           A +  P  ++ P    + F++LT +++     A L ++ +   + QLG++L  P + +  
Sbjct: 88  AYIETPFVKILPVNLGQPFTILTGLQSHRVNNAFLFSIRNKNRL-QLGVQL-LPKKLVVH 145

Query: 126 DQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRV--TRPLPRSARPVL 183
            +        QP     S+ D +WH  A+ ++ QSV++ V+C K+   T  +P       
Sbjct: 146 IRG------KQPAVFNYSVHDEQWHSFAITIRNQSVSMFVECGKKYFSTETIPEV--QTF 197

Query: 184 DTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQP 241
           D++ V   G+   +   FEG V +L I+P  +A+ + C   + +C    + +P+   P
Sbjct: 198 DSNSVFTLGSMNNNSIHFEGIVCQLDIIPSAEASADYCRYVKQQCRQADKYQPETSIP 255


>gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens]
          Length = 1712

 Score =  832 bits (2150), Expect = 0.0
 Identities = 547/1334 (41%), Positives = 634/1334 (47%), Gaps = 216/1334 (16%)

Query: 291  GPRGLKGEKGEPAVL-------------EPGML-VEGPPGPEGPAGLIGPPGIQGNPGPV 336
            GP+G KG+KGEP  L             EPG++  +GPPG  G  G +GP G  G PGP 
Sbjct: 160  GPQGPKGQKGEPYALPKEERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPP 219

Query: 337  GDPGERGPPGRAGL--------PGSDGAPGPPG--TSLMLPFRFGSG--------GGDKG 378
            G PG +G  G  GL         G  G PGP G  +  + P    +G         G+KG
Sbjct: 220  GPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKG 279

Query: 379  PVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGP 438
               +  E   + I  +    + G PG  GY G  G  G PG  G +G  G  GP GPRGP
Sbjct: 280  ---SEGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGP 336

Query: 439  QGLTGPPGKAG-------------RRGRAGADGARGMPGDPGVKGDRGFDGLPGL----- 480
            +G  G PG  G              RG  G  GA+G PG  G  GD G  G PGL     
Sbjct: 337  KGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDG 396

Query: 481  ------PGEKGHRGDTGAQGLP----GPPGEDGERGDDGEIGPRGLPGESGPRGLL---- 526
                  PGE G +G  G  G+P    GPPG DG+RG  G   P GLPG  GP G L    
Sbjct: 397  DQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPG---PPGLPGPPGPDGFLFGLK 453

Query: 527  GPKGPPGIPGPPGVRGMDGPQGPKGSLGP----QGEPGPPGQQGTPGTQGLPGPQGAIGP 582
            G KG  G PG PG  G  GP+G KG  G     +G+    G  G PG +G  G  G  G 
Sbjct: 454  GAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGR 513

Query: 583  HGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGP---SGPQGPLGYPGPRGVKG- 638
             G++G  G+ GLPG PG  G PG+ G  GP G KG+       G +G  G PG  G+KG 
Sbjct: 514  KGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGD 573

Query: 639  --------VDGIRGLKGHKGE--KGEDGFPGFKGDIGVKGDRGEVG-----VPGSRGEDG 683
                    +DG  GL G  G+  KG  G PG+ G  G KG  GE+G     +PG +G+ G
Sbjct: 574  DGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRG 633

Query: 684  PEGPKGRTGPTGDPGPPGLMGEKGKL---------------------------GVPGLPG 716
              G  G  GP G  GPPG  G  G++                           G+PGLPG
Sbjct: 634  FPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPG 693

Query: 717  YPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTG---PRGQRGPRGATGKSG 773
             PG  G KG  G PGF GA G  G RGL G +G  G  GP G   PRG +G  G  G  G
Sbjct: 694  PPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDG 753

Query: 774  AKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTG 833
            + G  G  GP GPPGERGLPG +     PGP+G  G PG+ GL G PG RG  GF+G  G
Sbjct: 754  SPGPIGLPGPDGPPGERGLPG-EVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQG 812

Query: 834  PPG------PPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPG 887
             PG       PG+ GP G  G  GP G  G PG PG  G  GLPG  G+EG  GD G PG
Sbjct: 813  MPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPG 872

Query: 888  APGKDGPAGLRGFPGERG---------------------LPGTAG--------------- 911
              G  GP G++G  G+RG                     +PGT G               
Sbjct: 873  DTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQG 932

Query: 912  GPGLKGNEGPSGPPGPAGS---PGERGAAGSGGPIGPPGRPGPQGPPGAA--GEKGVPGE 966
             PGLKG  G  G  G AG    PG +G AG  G  G  G PGP GPP     G K + GE
Sbjct: 933  MPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGE 992

Query: 967  KGPIGPTG------RDGVQGPVGLPGPAGPPGVAGEDGD----KGEVGDPGQKGTKGNKG 1016
            KG  GP G        G+QG  G+PG +G PG+ G  G     KG++G PG  G  G  G
Sbjct: 993  KGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPG 1052

Query: 1017 EHGPPGP---PGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE----GTRGFNGPPGPI 1069
              GPPG    PG IG  G  GA G  G  G  G  G FG  GD     G  G  G  G  
Sbjct: 1053 VAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTT 1112

Query: 1070 GLQGLPGPSGEKGETGDVG------PMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPP 1123
            G+ GL G  GEKG  GD+G        G  GPPG +G  G  G  GP G  G +G +G P
Sbjct: 1113 GIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLP 1172

Query: 1124 GEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGP--------PGPKGPTGDDG 1175
            G KG+ G  G+PG+ G PG++G RG  G  G  G PG PG         PGP G  GD G
Sbjct: 1173 GGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPG 1232

Query: 1176 PKGN-PGPVGFPG---DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPL 1231
                 PGPVG PG   D G PGE GP G  G +G  G        G+PG  G  G  G  
Sbjct: 1233 EANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLK 1292

Query: 1232 GKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL------RGLP 1285
            G RGP G PGS    G KG  G+PGA G PG  G  G +GP G+PG  GL      RG  
Sbjct: 1293 GYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQ 1352

Query: 1286 GSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLI----GLIGPPGEQGE 1341
            G +G  G  GA G  GP GP G PG PG  G  GA G  G P  I    G +GP G +G 
Sbjct: 1353 GFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGP 1412

Query: 1342 KGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGV 1401
             G  G  GPQG PG+ G  G PG +GP G GG   +PG  G +G  G  GP G +G  G 
Sbjct: 1413 PGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGR 1472

Query: 1402 QGPPGHPGPPGEVI 1415
             G PG PG PG  +
Sbjct: 1473 PGSPGLPGMPGRSV 1486



 Score =  816 bits (2108), Expect = 0.0
 Identities = 565/1412 (40%), Positives = 650/1412 (46%), Gaps = 253/1412 (17%)

Query: 283  PPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGER 342
            PP  +   G +G KG+KGE     PG  V GP G  G  G+ G PG  G PG  G  G R
Sbjct: 74   PPGLQGFPGLQGRKGDKGERGA--PG--VTGPKGDVGARGVSGFPGADGIPGHPGQGGPR 129

Query: 343  GPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--GDKGPVVAAQEAQAQAILQQARLALR 400
            G PG  G  G+ G  GP G     P   G  G  G +GP    Q+ +  A+ ++ R   R
Sbjct: 130  GRPGYDGCNGTQGDSGPQGP----PGSEGFTGPPGPQGP--KGQKGEPYALPKEERDRYR 183

Query: 401  GPPGPMGYT------GRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPP--GKAGRRG 452
            G PG  G        GRPG +GQ G  G  G  G  GP GP+G QG  G    G  G +G
Sbjct: 184  GEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKG 243

Query: 453  RAGADGARGMPGD--------PGV-------KGDRGFDGLPGLPG--EKGHRGDTGAQGL 495
              G  G  G+P D         GV       KG++G +G PG+ G   KG  G  G  GL
Sbjct: 244  DVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFPGL 303

Query: 496  PGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV-------------RG 542
             G PG  GE+G  G+ G RGL G  GP G  GPKG  G PGPPG+             RG
Sbjct: 304  RGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARG 363

Query: 543  MDGPQGPKGSLGPQGEPGPPGQQGTPG--------TQGLP---GPQGAI----------- 580
              G  G +G  G QGEPG PG  G PG         +GLP   GP+G I           
Sbjct: 364  DPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGG 423

Query: 581  --GPHGEKGPQGKPGLPGMPGSD----------------GPPGHPGKEGPPGTKGN---- 618
              GP G++GP G PGLPG PG D                G PG PG  GP G KG+    
Sbjct: 424  PPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGEC 483

Query: 619  ---QGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF--------------- 660
               +G    +G  G PGP+G  G++G  G KG +G+ G+ G PGF               
Sbjct: 484  RCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGP 543

Query: 661  ---KGD---IGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGE--KGKLGVP 712
               KGD   I  KG+RG+ GVPG  G  G +G  GR G  G PG PG  G+  KG  G P
Sbjct: 544  KGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDP 603

Query: 713  GLPGYPGRQGPKGSLGFP--GFPGASGEKGARGLSGKSGPRGERGPTGPRGQRG------ 764
            G PG PG +G  G +G P  G PG  G++G  G +G  GP G  GP GP G  G      
Sbjct: 604  GYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDT 663

Query: 765  ---------------PRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPG 809
                           P    G  G  G  G  GP G  G RG+PG  G +G PGP+G PG
Sbjct: 664  DVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPG 723

Query: 810  PPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHP---------- 859
              G++G PG PG  G  G +G  G PGP G  GP G  G  GP GERG P          
Sbjct: 724  DAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGP 783

Query: 860  -------------------GPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGF 900
                               GPPG  G QG+PG  G +G  G PGP G PG  GP GL GF
Sbjct: 784  RGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGF 843

Query: 901  PGERGLPGTAGGPGLKGNE---GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGA 957
            PG  G  G  G PG+ G E   G  G PG  G+PG  G  G  G  G  G  G QG PG+
Sbjct: 844  PGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGS 903

Query: 958  AGEKGV---PGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGN 1014
             G KG+   PG  G  G  G  G+ G  G+PG  G PG  G  G+ G  G PG KG  G 
Sbjct: 904  PGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGE 963

Query: 1015 ---KGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGL 1071
               KG  G PGPPGP  PV  PG     GE G  GP G  G  G +G +G  G PG  G+
Sbjct: 964  PGFKGSRGDPGPPGP-PPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGI 1022

Query: 1072 QGLPGPSGE-KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1130
             GLPG  G  KG  GD+G  G PG PG  G AGP G  G  G  G  G+ G PG  G  G
Sbjct: 1023 PGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYG 1082

Query: 1131 ESGSPG----------IQGEPGVKGPRGE------RGEKGESGQPGEPGPPGPKGPTGDD 1174
            E G+ G          + G PG+KG RG       +G  GE G  G+ G PG  G TG  
Sbjct: 1083 EIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQ 1142

Query: 1175 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1234
            GP G  G  GFPG  GPPG  G  G+ G  G +G+DG PG PG PG  G  G  G  G  
Sbjct: 1143 GPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLP 1202

Query: 1235 GPAGSPGSEGR--QGGKGAKGDPGAIGAPGKT----GPVGPAGPAGKPGPDGLRGLPGSV 1288
            G  G PGS G    G  G  G PG  G PG+     GPVG  G  G  G  G RG PGS 
Sbjct: 1203 GTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPGSP 1262

Query: 1289 GQQGRPGAT---------------------GQAGPPGPVGPPGLPGLRGDAGAKGEKGHP 1327
            G QG PG T                     G  GPPGP G   LPG +GD G  G  G P
Sbjct: 1263 GLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTP 1322

Query: 1328 GLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGAS------GPIGPGGPPGLPGPA 1381
            G  G  G  G QG  G  GLPG +G  G++G MG  G +      GP GP G PG PG  
Sbjct: 1323 GTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAP 1382

Query: 1382 GPKGAKGATG--------PG--GPKGEKGVQGPPGHPGPPGEVIQP----LPIQMPKKTR 1427
            G  GA G  G        PG  GP+G +G  G PG  GP G   +P     P +   + R
Sbjct: 1383 GTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGR 1442

Query: 1428 RSVDGSRLMQEDEA-------IPTGGAPGSPG 1452
              V      + DE        I   GAPG PG
Sbjct: 1443 GGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPG 1474



 Score =  773 bits (1996), Expect = 0.0
 Identities = 527/1293 (40%), Positives = 610/1293 (47%), Gaps = 269/1293 (20%)

Query: 400  RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 459
            RG PGP+G  G  GP G  G PGL+G  GD   +G RG  G+TGP G  G RG +G  GA
Sbjct: 60   RGQPGPVGPQGYNGPPGLQGFPGLQGRKGD---KGERGAPGVTGPKGDVGARGVSGFPGA 116

Query: 460  RGMPGDPGVKGDR---GFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGL 516
             G+PG PG  G R   G+DG  G  G+ G +G  G++G  GPPG  G +G  GE  P  L
Sbjct: 117  DGIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGE--PYAL 174

Query: 517  P--------GESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT- 567
            P        GE G  GL+G +GPPG PG     G  GP G  G  GP G PGP GQQG  
Sbjct: 175  PKEERDRYRGEPGEPGLVGFQGPPGRPGHV---GQMGPVGAPGRPGPPGPPGPKGQQGNR 231

Query: 568  ----------PGTQGLPGPQG--------AIGP----------HGEKGPQGKPGLPGM-- 597
                       G  G PGP G         I P           GEKG +G+PG+ G+  
Sbjct: 232  GLGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISL 291

Query: 598  ---------PGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH 648
                     PG  G PG  G++G PG KG++G  G QGP G  GP+G  G  G  GL  +
Sbjct: 292  KGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAY 351

Query: 649  -------KGEKGEDGFPGFKGDIGVKGDRGEVGVPG-----------SRGEDGPEGPKGR 690
                   KG +G+ GFPG +G+ G +G+ G+ G+PG            RG  G  GPKG 
Sbjct: 352  SPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGF 411

Query: 691  TGPTGDP----GPPGLMGEKGKLGVPGLPGYP-------GRQGPKGSLGFPGFPGASGEK 739
             G  G P    GPPG  G++G  G PGLPG P       G +G KG  GFPG PG+ G +
Sbjct: 412  IGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGAR 471

Query: 740  GARGLSGKSG----PRGERGPTGPRGQRGPR---GATGKSGAKGTSGGDGPHGPPGERGL 792
            G +G  G +G      G+    G  G  GP+   G  G+ G KG  G  G HG PG  GL
Sbjct: 472  GPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGL 531

Query: 793  PGPQGPNGFPGPKGP------------------PGPPGKDGLPGHPGQRGEVGFQGKTGP 834
             G  G  G PGPKG                   PG PG  G  G PG+ G  GF G  GP
Sbjct: 532  KGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGP 591

Query: 835  PGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGP 894
            PG  G+ GP G  G  G  G +G PG  GPPG  GLPG  G+ G  GD G PG PG  GP
Sbjct: 592  PG-DGIKGPPGDPGYPGIPGTKGTPGEMGPPG-LGLPGLKGQRGFPGDAGLPGPPGFLGP 649

Query: 895  AGLRGFPG-----------------ERGLPGTAGG----PGLKGNEGPSGPPGPAGSPGE 933
             G  G PG                 E   PG  GG    PGL G  GP+G  G  G PG 
Sbjct: 650  PGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGF 709

Query: 934  RGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGV 993
             GA G  GP G PG  G +G PG  G  G  G KG +G  G DG  GP+GLPGP GPPG 
Sbjct: 710  AGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGE 769

Query: 994  AG--------EDGDKGEVGDPGQKGTKGNKGEHGPP------GPPGPIGPVGQPGAAGAD 1039
             G        + G +G+ G PGQ G KG  G+ GPP      G PG  G  GQPG  G  
Sbjct: 770  RGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPS 829

Query: 1040 GEPGARGP---------------------QGHFGAKGDEGTRGFNGPPGPIGLQGLPGPS 1078
            G+PG  GP                      G  G  GD G  G  G PGP+G++GL G  
Sbjct: 830  GQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDR 889

Query: 1079 GEKGETGDVGPMGP---------PGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP 1129
            G+ G TG+ G  G          PG PG +G  G  G DG QG PG  G  G PG KGE 
Sbjct: 890  GDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEA 949

Query: 1130 GESGSPGIQ---GEPGVKGPRGE-----------------RGEKGE-------------- 1155
            G  G PG++   GEPG KG RG+                 +GEKG+              
Sbjct: 950  GFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKG 1009

Query: 1156 ----------SGQPGEPGPPGP-KGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAK 1204
                      SG PG PG PG  KG  GD G  G PG  GFPG  GPPG  G  G  G++
Sbjct: 1010 IQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSR 1069

Query: 1205 GDRGEDGEPGQPGSPGPTGE----------NGPPGPLGKRGPAGSPGSEGRQGGKGAKGD 1254
            GD+G  G  G  G  G TG+           G PG  G+RG  G PG +G  G KG +GD
Sbjct: 1070 GDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGD 1129

Query: 1255 PGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGR---PGATGQAGPPGPVGPPGL 1311
             G  G  G TG  GP G  G+ G  GL G PGS G+ GR   PG  G  G PG  G PG 
Sbjct: 1130 IGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGF 1189

Query: 1312 PGLRGDA---GAKGEKGHPGL--------IGLIGPPGEQGEKGDRG-LPGPQGSPGQKGE 1359
            PGLRG     G  G KG PG          G  GPPGE+G+ G+   LPGP G PGQKG+
Sbjct: 1190 PGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGD 1249

Query: 1360 MGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1419
             G PG  GP G  G  G PG   P    GA G  G  G  G++G  G PGPPG    P  
Sbjct: 1250 QGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALP-- 1307

Query: 1420 IQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1452
                        GS+    D   P  GAPG+PG
Sbjct: 1308 ------------GSK---GDTGNP--GAPGTPG 1323



 Score =  752 bits (1942), Expect = 0.0
 Identities = 494/1219 (40%), Positives = 568/1219 (46%), Gaps = 208/1219 (17%)

Query: 291  GPRGLKGEKGEPAV-----LEPGMLVEGPPGPEGPAGLIGPPGI----------QGNPGP 335
            G  GL GEKG P       L+     +GP GP+G AG  GPPG+          +G  G 
Sbjct: 305  GYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGD 364

Query: 336  VGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQA 395
             G PG +G PG  G PG  G PGPPG S+        G GD+   +  +      I    
Sbjct: 365  PGFPGAQGEPGSQGEPGDPGLPGPPGLSI--------GDGDQRRGLPGEMGPKGFIGDPG 416

Query: 396  RLALRG-PPGPMGYTGRPGPLGQPGSPG-------LKGESGDLGPQGPRGPQGLTGPPGK 447
              AL G PPGP G  G PGP G PG PG       LKG  G  G  G  G  G  GP G 
Sbjct: 417  IPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGW 476

Query: 448  AGRRGRAGA-DGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERG 506
             G  G     +G   + G PG+ G +GF G+ G PG KG RGD G  GLPG PG  G  G
Sbjct: 477  KGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPG 536

Query: 507  DDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQ-- 564
            + G  GP+G  G+S      G +G PG+PG PG++G DG  G  G  G  G PGPPG   
Sbjct: 537  NIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGI 596

Query: 565  QGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSG- 623
            +G PG  G PG  G  G  GE GP G  GLPG+ G  G PG  G  GPPG  G  GP+G 
Sbjct: 597  KGPPGDPGYPGIPGTKGTPGEMGPPGL-GLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGT 655

Query: 624  -----------------------------PQGPLGYPGPRGVKGVDGIRGL--------- 645
                                         P+G  G PGP G  G  G+RG+         
Sbjct: 656  PGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGG 715

Query: 646  ---KGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTG------- 695
               +G  G+ G +GFPG  G IG +G +G VG+PG  G  GP G  G  GP G       
Sbjct: 716  PGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGE 775

Query: 696  -------------------------DPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLG-- 728
                                     D GPPG  G +G  G+PGL G PG  GP G  G  
Sbjct: 776  VLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLY 835

Query: 729  -------FPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGD 781
                   FPG PG  G  G  G+ G+ G  G+RG  G  G  GP G  G SG +G +G  
Sbjct: 836  GPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFT 895

Query: 782  GPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVV 841
            G  G PG  G  G  G  G PG KG  G PG DG  G PG +G  GF G  G  G  G+ 
Sbjct: 896  GEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIP 955

Query: 842  GPQGAAGETGPMGERGHPGPPGPP--------------------------GEQGLPGTAG 875
            G +G AGE G  G RG PGPPGPP                          G +G+ G  G
Sbjct: 956  GLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPG 1015

Query: 876  KEGTKGDPGPPGAPGK----------DGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPP 925
              G  G PG PG PG            G  GL GFPG  G PG  G PG  G+ G  G P
Sbjct: 1016 IPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAP 1075

Query: 926  GPAGSPGERGAAGSGGPIGP----PGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGP 981
            G AG  GE GA G  G IG     PGRPG +G  G  G   +PG KG  G     G +G 
Sbjct: 1076 GRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTG---IPGLKGFFG---EKGTEGD 1129

Query: 982  VGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGE 1041
            +G PG  G  GV G  G KG+ G PG  G  G++GE G  G PG  G  G PGA G  G 
Sbjct: 1130 IGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGF 1189

Query: 1042 PGARGPQGHFGAKGDEGTRGFNGPPGPI--GLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1099
            PG RG +G  G  G   T+GF G PG    G  G PGP GE+G+ G+   +  PGP G  
Sbjct: 1190 PGLRGIRGLHGLPG---TKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTL--PGPVGVP 1244

Query: 1100 GPAGPNGADGPQGPPGGVGNLGPPGE------KGEPGESGSPGIQGEPGVKGPRGERGE- 1152
            G  G  GA G +GPPG  G  G PG        G PG+ G+PGI G  G +GP G  G  
Sbjct: 1245 GQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSA 1304

Query: 1153 -----KGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGG---PRGQDGAK 1204
                 KG++G PG PG PG KG  GD GP+G PG  G PG+ GP GE G     G  GA 
Sbjct: 1305 ALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAV 1364

Query: 1205 GDRGEDGEPGQPGSPGPTGENGPPGPLG-KRGPAGSPGSEGRQGGKGAKGDPGAIGAPGK 1263
            GDRG  G  G PG PG  G  G PG  G  +  A  PG+ G QG +G  G      APG+
Sbjct: 1365 GDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPG------APGE 1418

Query: 1264 TGPVGPAGPAGKPGPDGLRGLPGSVGQQGR------PGATGQAGP---PGPVGPPGLPGL 1314
             GP GP      PG  G RG PG  G QGR      PG  G  GP    GP+G  G PG 
Sbjct: 1419 MGPQGP------PGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGR 1472

Query: 1315 RGDAGAKGEKGHPGLIGLI 1333
             G  G  G  G    IG +
Sbjct: 1473 PGSPGLPGMPGRSVSIGYL 1491



 Score =  616 bits (1588), Expect = e-176
 Identities = 406/1028 (39%), Positives = 472/1028 (45%), Gaps = 178/1028 (17%)

Query: 284  PLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 343
            P    A GP+G KG+ GE    E    ++G PG  GP G  G  G  G  G  GDPG+ G
Sbjct: 465  PGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHG 524

Query: 344  PPGRAGL---PGSDGAPGPPGT-----SLMLPFRFGSGG--------GDKGPVVAAQEAQ 387
             PG  GL   PG+ GAPGP G      ++      G  G        GD G         
Sbjct: 525  LPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDG 584

Query: 388  AQAILQQARLALRGPPGPMGYTGRPGPLGQPGS--------PGLKGESGDLGPQGPRGPQ 439
               +       ++GPPG  GY G PG  G PG         PGLKG+ G  G  G  GP 
Sbjct: 585  FPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPP 644

Query: 440  GLTGPPGKAGRRGR------------------------AGADGARGMPGDPGVKGDRGFD 475
            G  GPPG AG  G+                         G  G  G+PG PG  G +G  
Sbjct: 645  GFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLR 704

Query: 476  GLPGL------PGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPK 529
            G+PG       PG +G  GD G +G PGPPG  G RG  G +G  G  G  GP GL GP 
Sbjct: 705  GIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPD 764

Query: 530  GPP--------------------GIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPG 569
            GPP                    G+PG PG++G+ G +GP G  G QG PG PG +G P 
Sbjct: 765  GPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQP- 823

Query: 570  TQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPL- 628
              GLPGP G  G +G  G  G PG PG  G  G PG PG+EG PG +G+ G +G  GP+ 
Sbjct: 824  --GLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVG 881

Query: 629  -----------------GYPGPRGVKGVDGIRGLKGHKGE---------------KGEDG 656
                             G+PG  G KG+DG+ G  G KG+               KG  G
Sbjct: 882  MKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPG 941

Query: 657  FPGFKGDI------GVKGDRGEVGVPGSRGEDGPEGP--------KGRTGPTGDPGPPGL 702
            FPG KG+       G+KG  GE G  GSRG+ GP GP        K   G  GD GP GL
Sbjct: 942  FPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGL 1001

Query: 703  MGEKGKLGVPGLPGYPGR-------------QGPKGSL------GFPGFPGASGEKGARG 743
             G  G  G+ G+PG PG              +G KG +      G PGFPG +G  G  G
Sbjct: 1002 KGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITG 1061

Query: 744  LSGKSGPRGERGPTGPRGQRGPRGATGKSGAKG-TSGGDGPHGPPGERGLPGPQGPNGFP 802
              G  G RG++G  G  G  G  GATG  G  G T    G  G  GERG  G  G  GF 
Sbjct: 1062 FPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFF 1121

Query: 803  GPKGP------PGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGER 856
            G KG       PG  G  G+ G PG +G+ GF G TGPPG  G +G  G  G  G  G  
Sbjct: 1122 GEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWP 1181

Query: 857  GHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGA-----PGKDGPAGLRGFPGERG-LPGTA 910
            G PG PG PG +G+ G  G  GTKG PG PG+     PG  GP G RG PGE   LPG  
Sbjct: 1182 GAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPV 1241

Query: 911  GGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPI 970
            G PG KG++G  G  GP GSPG +G  G   P    G PG +G PG  G KG  G  GP 
Sbjct: 1242 GVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPP 1301

Query: 971  GPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP---GQKGTKGNKGEHGPPGPPGPI 1027
            G     G +G  G PG  G PG  G  GD G  G P   G  G KG +GE G  G  GP 
Sbjct: 1302 GSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPT 1361

Query: 1028 GPVGQPGAAGADGEPGARGPQGHFGA-------------KGDEGTRGFNGPPGPIGLQGL 1074
            G VG  G  G  G+PG  G  G  GA              G  G +G  GPPG  G  G 
Sbjct: 1362 GAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGP 1421

Query: 1075 PGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGS 1134
             GP GE G  G  G  GP G  G     G  G +GP      +G+ GP G++G PG  GS
Sbjct: 1422 QGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGP------IGHQGPIGQEGAPGRPGS 1475

Query: 1135 PGIQGEPG 1142
            PG+ G PG
Sbjct: 1476 PGLPGMPG 1483



 Score =  612 bits (1579), Expect = e-175
 Identities = 407/1007 (40%), Positives = 475/1007 (47%), Gaps = 185/1007 (18%)

Query: 616  KGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF---KGDIGVKGDRGE 672
            KG +G  GP GP GY GP G++G  G   L+G KG+KGE G PG    KGD+G +G  G 
Sbjct: 57   KGGRGQPGPVGPQGYNGPPGLQGFPG---LQGRKGDKGERGAPGVTGPKGDVGARGVSGF 113

Query: 673  VGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFP-- 730
             G  G  G  G  GP+GR G  G  G  G  G +G  G  G  G PG QGPKG  G P  
Sbjct: 114  PGADGIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYA 173

Query: 731  ----------GFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGG 780
                      G PG  G  G +G  G+ G  G+ GP G  G+ GP G  G  G +G + G
Sbjct: 174  LPKEERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQG-NRG 232

Query: 781  DGPHGPPGERGLPGPQGPNGFP---------------------GPKGPPGPP-------- 811
             G +G  GE+G  G  GPNG P                     G KG  G P        
Sbjct: 233  LGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLK 292

Query: 812  GKDGLPGHPGQRGEVGFQGKTGPPGPP---GVVGPQGAAGETGPMGERGHPGPPGPP--- 865
            G++G+ G PG RG  G  G+ G PG     G+ G QG  G  GP GE G PGPPG P   
Sbjct: 293  GEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYS 352

Query: 866  ----------GEQGLPGTAGKEGTKGDPGPPGAPGK--------------DGPAGLRGFP 901
                      G+ G PG  G+ G++G+PG PG PG                G  G +GF 
Sbjct: 353  PHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFI 412

Query: 902  GERGLPGTAGG-PGLKGNEGPSGPPGPAGSPGERG-AAGSGGPIGPPGRPGPQGPPGAAG 959
            G+ G+P   GG PG  G  GP GPPG  G PG  G   G  G  G  G PG  G PGA G
Sbjct: 413  GDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARG 472

Query: 960  EKGVPGEKGPIGPT-GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKG-------- 1010
             KG  G+ G    T G + ++G  GLPGP G  G+ GE G KG+ GDPGQ G        
Sbjct: 473  PKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLK 532

Query: 1011 ----------------------TKGNKGEHGPPGPPGPIGPVGQPGAAGADGEP------ 1042
                                  TKG +G+ G PG PG  G  G PG  G DG P      
Sbjct: 533  GVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPP 592

Query: 1043 --GARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG 1100
              G +GP G  G  G  GT+G  G  GP GL GLPG  G++G  GD G  GPPG  GP G
Sbjct: 593  GDGIKGPPGDPGYPGIPGTKGTPGEMGPPGL-GLPGLKGQRGFPGDAGLPGPPGFLGPPG 651

Query: 1101 PAG------------------------PNGADGPQGPPGGVGNLGPPGEKGEPGESGSPG 1136
            PAG                        P    GP+G PG  G  GP G KG  G  G  G
Sbjct: 652  PAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAG 711

Query: 1137 IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGG 1196
              G PG +G  G+ G +G  G PG  GP G KG  G  GP G+PGP+G PG  GPPGE G
Sbjct: 712  ADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERG 771

Query: 1197 PRGQ--DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGD 1254
              G+      G RG+ G PGQPG  G  G+ GPPG  G +G  G PG +G+ G  G  G 
Sbjct: 772  LPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQ 831

Query: 1255 PGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGL 1314
            PG  G PG  G   P  P G+ GP GL G+PG  G  G  G  G  G PGPVG  GL G 
Sbjct: 832  PGLYGPPGLHG--FPGAP-GQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGD 888

Query: 1315 RGDAGAKGEKGH---PGLIGLIGPPGEQGEKGDRGLPGP---QGSPGQKGEMGIPGASGP 1368
            RGDAG  GE+GH   PG  G+ G PG  G KGDRG PG    QG PG KG  G PG+ G 
Sbjct: 889  RGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGE 948

Query: 1369 IGPGGPPGLPGPAGPKGAKGATGPGGP--------------KGEKGVQGPPGHPGPPGEV 1414
             G  G PGL G AG  G KG+ G  GP              KGEKG +GP G  G  G  
Sbjct: 949  AGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLG-- 1006

Query: 1415 IQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSL 1461
                         + + G   +     IP  G PG PG ++ + G +
Sbjct: 1007 ------------AKGIQGMPGIPGLSGIP--GLPGRPGHIKGVKGDI 1039



 Score =  498 bits (1281), Expect = e-140
 Identities = 331/793 (41%), Positives = 377/793 (47%), Gaps = 121/793 (15%)

Query: 764  GPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQR 823
            G R  +G        GG G  GP G +G  GP G  GFPG +G  G  G+ G PG  G +
Sbjct: 43   GGRDCSGGCQCYPEKGGRGQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPK 102

Query: 824  GEVG------FQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKE 877
            G+VG      F G  G PG PG  GP+G  G  G  G +G  GP GPPG +G  G  G +
Sbjct: 103  GDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQ 162

Query: 878  GTKGDPGPP------------GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPP 925
            G KG  G P            G PG+ G  G +G PG  G  G  G  G  G  GP GPP
Sbjct: 163  GPKGQKGEPYALPKEERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPP 222

Query: 926  GPAGSPGERGAA--GSGGPIGPPGRPGPQGPPGAA------------------GEKGVPG 965
            GP G  G RG    G  G  G  G+PGP G P                     GEKG  G
Sbjct: 223  GPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEG 282

Query: 966  EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG 1025
            E G I      G +G +G PG  G PG++GE       G PGQKG++G  G  GP GP G
Sbjct: 283  EPG-IRGISLKGEEGIMGFPGLRGYPGLSGEK------GSPGQKGSRGLDGYQGPDGPRG 335

Query: 1026 PIGPVGQPG-------------AAGADGEPGARGPQGHFGAKGDEGTRGFNGPPG-PIG- 1070
            P G  G PG             A GA G+PG  G QG  G++G+ G  G  GPPG  IG 
Sbjct: 336  PKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGD 395

Query: 1071 ---LQGLPGPSGEKGETGDVGPM----GPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPP 1123
                +GLPG  G KG  GD G      GPPGP G RGP GP G  GP GP G +  L   
Sbjct: 396  GDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGL--- 452

Query: 1124 GEKGEPGESGSPGIQGEPGVKGPRGERGEKGE----------SGQPGEPGP--------- 1164
              KG  G +G PG+ G PG +GP+G +G+ GE           G PG PGP         
Sbjct: 453  --KGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGE 510

Query: 1165 PGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGD------RGEDGEPGQPGS 1218
            PG KG  GD G  G P   GFPG  G PG  G  G  GAKGD      +GE G+PG PG 
Sbjct: 511  PGRKGDRGDPGQHGLP---GFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGV 567

Query: 1219 PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGP 1278
            PG  G++G PG  G  G  G PG  G  G KG  GDPG  G PG  G  G  GP G  G 
Sbjct: 568  PGMKGDDGSPGRDGLDGFPGLPGPPG-DGIKGPPGDPGYPGIPGTKGTPGEMGPPGL-GL 625

Query: 1279 DGLRGLPGSVGQQGRPGATGQAGPPGPVGPPG-----------LPGLRGDAGAKGEKGHP 1327
             GL+G  G  G  G PG  G  GPPGP G PG           + G R +A   G  G P
Sbjct: 626  PGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGP 685

Query: 1328 -GLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGA 1386
             GL GL GPPG  G KG RG+PG  G+ G  G  G+PG +G  G  GPPG  GP G KGA
Sbjct: 686  KGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGA 745

Query: 1387 KGATGPG---GPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP 1443
             G  GP    GP G  G  GPPG  G PGEV+   P            G + +  D   P
Sbjct: 746  VGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPP 805

Query: 1444 ----TGGAPGSPG 1452
                + G PG PG
Sbjct: 806  GFRGSQGMPGMPG 818



 Score =  254 bits (648), Expect = 6e-67
 Identities = 183/490 (37%), Positives = 214/490 (43%), Gaps = 108/490 (22%)

Query: 1059 TRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVG 1118
            T GF       G++    P G +  +G        G  G  GP GP G +   GPPG  G
Sbjct: 23   TVGFLAQSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQGYN---GPPGLQG 79

Query: 1119 NLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK---------G 1169
              G  G KG+ GE G+PG+ G  G  G RG  G  G  G PG PG  GP+         G
Sbjct: 80   FPGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNG 139

Query: 1170 PTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGD------RGEDGEP------GQPG 1217
              GD GP+G PG  GF G PGP G  G +G+  A         RGE GEP      G PG
Sbjct: 140  TQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERDRYRGEPGEPGLVGFQGPPG 199

Query: 1218 SPGPTGENGPPGPLGKRGPAGSPGSEGRQGGK-----GAKGDPGAIGAPGKTG------- 1265
             PG  G+ GP G  G+ GP G PG +G+QG +     G KG+ G +G PG  G       
Sbjct: 200  RPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSDTLH 259

Query: 1266 PV--------------GPAGPAGKPGP--------------DGLRGLPGSVGQQGRPGAT 1297
            P+              G  G  G+PG                GLRG PG  G++G PG  
Sbjct: 260  PIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQK 319

Query: 1298 GQAGPPGPVGPPGLPGLRGDAG----------------AKGEKGHPGLIGLIGPPGEQGE 1341
            G  G  G  GP G  G +G+AG                AKG +G PG  G  G PG QGE
Sbjct: 320  GSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGE 379

Query: 1342 KGDRGLPGPQGSPGQKGEM--GIPGASGPIG----------PGGPPGLPGPAGPKGAKGA 1389
             GD GLPGP G     G+   G+PG  GP G           GGPPG  G  GP G  G 
Sbjct: 380  PGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGL 439

Query: 1390 TGPGGP-------KGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAI 1442
             GP GP       KG KG  G PG PG PG        + PK  +      R  + DEAI
Sbjct: 440  PGPPGPDGFLFGLKGAKGRAGFPGLPGSPG-------ARGPKGWKGDAGECRCTEGDEAI 492

Query: 1443 PTGGAPGSPG 1452
               G PG PG
Sbjct: 493  K--GLPGLPG 500



 Score =  244 bits (623), Expect = 5e-64
 Identities = 165/409 (40%), Positives = 194/409 (47%), Gaps = 54/409 (13%)

Query: 291  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGN------PGPVGDPGERGP 344
            GP GLKG+ G P +        GPPG +G  G IG PG +G+      PG  G PG RG 
Sbjct: 1143 GPPGLKGQTGFPGLT-------GPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGI 1195

Query: 345  PGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPG 404
             G  GLPG+ G PG PG+ +          GD G                      GPPG
Sbjct: 1196 RGLHGLPGTKGFPGSPGSDIH---------GDPG--------------------FPGPPG 1226

Query: 405  PMGYTGR----PGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGAR 460
              G  G     PGP+G PG    KG+ G  G +GP G  GL G PG       +GA G +
Sbjct: 1227 ERGDPGEANTLPGPVGVPGQ---KGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDK 1283

Query: 461  GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 520
            G PG  G+KG RG  G PG     G +GDTG  G PG PG  G  GD G   P+G PG  
Sbjct: 1284 GAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSG---PQGRPGVF 1340

Query: 521  GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAI 580
            G  G  GP+G  G  G  G  G  G +GPKG  G  G PG PG  G PG  G+P  + A+
Sbjct: 1341 GLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIP-QKIAV 1399

Query: 581  GPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVD 640
             P G  GPQG+ G PG PG  GP G PG+ G  G  G  GP G  G    PG RG +G  
Sbjct: 1400 QP-GTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPI 1458

Query: 641  GIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKG 689
            G +G  G +G  G  G PG  G  G     G + V  S+ +  P  P G
Sbjct: 1459 GHQGPIGQEGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVG 1507


>gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo
            sapiens]
          Length = 1691

 Score =  805 bits (2078), Expect = 0.0
 Identities = 548/1395 (39%), Positives = 640/1395 (45%), Gaps = 270/1395 (19%)

Query: 291  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPG---- 346
            G  GLKGE+G P +L P     GP G +GP G+ G  GI G PG  G PG RGPPG    
Sbjct: 71   GLSGLKGERGFPGLLGP----YGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGC 126

Query: 347  -----RAGLPGSDGAPG---PPGTS---------LMLPFRFGSGGGDKG-PVVAAQEAQA 388
                   G PG DG PG   PPG           ++ P  F    GD G P +       
Sbjct: 127  NGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQ 186

Query: 389  QAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGL-----KGESGDLGPQGPRGPQGLTG 443
             A      +   GPPG  G  G PGPLG  G+ GL     KG  GD+G  GP GP   TG
Sbjct: 187  GAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTG 246

Query: 444  -------PPGKAGRRGRAGADGARGMPGDPGV--------KGDRGFDGLPGLPGEKGHRG 488
                   P GK G +G  G  G  G+ G PG         KG++G  G+PGLPG +G  G
Sbjct: 247  ELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMG 306

Query: 489  DTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPK--------------GPPGI 534
              G QG PG  G+ G  G  G  G +G+ G+ G  GL GP               G PG+
Sbjct: 307  SEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGV 366

Query: 535  PGPPGVRGMDGPQGPKG---------------SLGPQGEPGPPGQQGTPGT--------- 570
            PG PG++G +G QG +G               +LGPQG PG  G QG PG          
Sbjct: 367  PGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLP 426

Query: 571  --QGLPGPQGAIGP--------------------HGEKGPQGKPGLPGMPGSDG------ 602
               GLPGP G  GP                     GE+GP+G  GL G+ G  G      
Sbjct: 427  GRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDG 486

Query: 603  ------PPGHPGKEGP---------PGTKGNQGPSGPQGPLGYPG---------PRGVKG 638
                  PPG PG  GP          G +G++G  G QGP G PG         P+G KG
Sbjct: 487  GVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKG 546

Query: 639  V---------------DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDG 683
                             G +G +G  GE G+DG PG  G  G+ GD G+ G PG +G  G
Sbjct: 547  EPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQ-GFPGEKGLPG 605

Query: 684  PEGPKGRTGPTGDPG--------PPGLMGEKGKLGVPGLPGYPGRQG---------PKGS 726
              G KG  GP G PG        P GL G+KGK G+PG  G PG +G           G 
Sbjct: 606  LPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGP 665

Query: 727  LGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRG------------PRGATGKSGA 774
             GFPG PG  G KG+RGL G  G  G  G  G  G  G            PRG  G  G 
Sbjct: 666  SGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGF 725

Query: 775  KGTSGGDGPHGPPGERGLPGPQGPNG--FPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKT 832
             G  G DG  G  G  GLPG +G  G  F    G PG  G  GL GH G  G+ G  G  
Sbjct: 726  PGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLK 785

Query: 833  GPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKD 892
            G  G PG++GP+G  G  G  G+ G PG PG  G  G+ G +G  G  G PG  G PGK 
Sbjct: 786  GVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKK 845

Query: 893  GPAGLRGFPG---ERGLPGTAG---GPGLKGNEGPSGPPGPAGSP---GERGAAGSGGPI 943
            G  G +G PG   ++GLPG  G    PGL G +G  G PG AG P   G +G  GS G +
Sbjct: 846  GTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFV 905

Query: 944  GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQG---------PVGLPGPAGPPG-- 992
            G PG PG  G PG  G KG+PG  G +GP+GR G  G         PVG+P P  P    
Sbjct: 906  GFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNL 965

Query: 993  -VAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPG----AAGADGEPGARGP 1047
             + G+ G +G  G  G  G +G+KGE G PGPPG  G  G PG     +G  G PG  G 
Sbjct: 966  WLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGI 1025

Query: 1048 QGHFGAKGDEGTRGFNGPPGPIGLQG------LPGPSGEKGETGDVGP-MGPPGPPGPRG 1100
            +G  G KG  G  GF G PG  G QG      LPG SG  G  GD G  +   G PGP+G
Sbjct: 1026 RGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKG 1085

Query: 1101 PAGPNGADGPQGPPGGVGNLGPPGEKGEPGE---SGSPGIQGEPGVKGPRGERGEKGESG 1157
              G +G  G +G  G +GN+G PG KGE G+   SG  G+ G PG  G  G RGE G  G
Sbjct: 1086 QPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPG 1145

Query: 1158 QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAK-----------GD 1206
              G  G  GP G  G  GPKG PG  G  G  G PG  G  G  G             G 
Sbjct: 1146 SSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGP 1205

Query: 1207 RGEDGEPG----QPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPG 1262
            +GE G PG     PG PG  G+ G  G  G +GPAG PG+ G        G PG  G PG
Sbjct: 1206 KGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPG 1265

Query: 1263 KTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKG 1322
              G  G  GPAG PGP G     G  G  G PG  G  GP G  G PG  GL G+ G KG
Sbjct: 1266 LDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKG 1325

Query: 1323 EKGHPGLIGL---IGPPGEQGEKGDRGLPGPQGSPGQKGE-------------------- 1359
             +G PG +G    +GPPG+ G  G +G  GP+GS G +G+                    
Sbjct: 1326 MRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLP 1385

Query: 1360 --------MGIPGASGPI---GPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHP 1408
                     G PGA GP+   G  G PG+PG  GP G  G  G  G  G  G+QGPPG  
Sbjct: 1386 GIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFE 1445

Query: 1409 GPPGEVIQPLPIQMP 1423
            G PG   Q  P  MP
Sbjct: 1446 GAPG---QQGPFGMP 1457



 Score =  800 bits (2066), Expect = 0.0
 Identities = 542/1356 (39%), Positives = 635/1356 (46%), Gaps = 242/1356 (17%)

Query: 290  HGPRGLKGEKGEPAVLE----PGMLVEGPPGPEGPAGLIGPPGIQGN---PGPVGDPGER 342
            +GP+G KG  G P  L     PG    G PGP GP GL G  G QG    PGP G PG  
Sbjct: 88   YGPKGDKGPMGVPGFLGINGIPGH--PGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLL 145

Query: 343  GPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKG-PVVAAQEAQAQAILQQARLALRG 401
            GPP   GLPG  G+ G P   ++ P  F    GD G P +        A      +   G
Sbjct: 146  GPP---GLPGQKGSKGDP---VLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAG 199

Query: 402  PPGPMGYTGRPGPLGQPGSPGL-----KGESGDLGPQGPRGPQGLTG-------PPGKAG 449
            PPG  G  G PGPLG  G+ GL     KG  GD+G  GP GP   TG       P GK G
Sbjct: 200  PPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKG 259

Query: 450  RRGRAGADGARGMPGDPGV--------KGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGE 501
             +G  G  G  G+ G PG         KG++G  G+PGLPG +G  G  G QG PG  G+
Sbjct: 260  SKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGK 319

Query: 502  DGERGDDGEIGPRGLPGESGPRGLLGP--------------KGPPGIPGPPGVRGMDGPQ 547
             G  G  G  G +G+ G+ G  GL GP               G PG+PG PG++G +G Q
Sbjct: 320  KGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQ 379

Query: 548  GPK---------------GSLGPQGEPGPPGQQGT-----------PGTQGLPGPQGAIG 581
            G +               G+LGPQG PG  G QG            PG  GLPGP G  G
Sbjct: 380  GLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPG 439

Query: 582  P--------------------HGEKGPQGKPGLPGMPG------------SDGPPGHPGK 609
            P                     GE+GP+G  GL G+ G            + GPPG PG 
Sbjct: 440  PPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGP 499

Query: 610  EGP---------PGTKGNQGPSGPQGPLGYP---------GPRGVKGV------------ 639
             GP          G +G++G  G QGP G P         GP+G KG             
Sbjct: 500  PGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGD 559

Query: 640  ---DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGP--- 693
                G +G +G  GE G+DG PG  G  G+ GD G+ G PG +G  G  G KG  GP   
Sbjct: 560  RGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQ-GFPGEKGLPGLPGEKGHPGPPGL 618

Query: 694  -----TGDPGPPGLMGEKGKLGVPGLPGYPGRQ---------GPKGSLGFPGFPGASGEK 739
                  G PGP GL G+KGK G+PG  G PG +         G  G  GFPG PG  G K
Sbjct: 619  PGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPK 678

Query: 740  GARGLSGKSGPRGERGPTGPRGQ------------RGPRGATGKSGAKGTSGGDGPHGPP 787
            G+RGL G  G  G  G  G  G              GPRG  G  G  G  G DG  G  
Sbjct: 679  GSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMI 738

Query: 788  GERGLPGPQGPNG--FPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQG 845
            G  GLPG +G  G  F    G PG  G  GL GH G  G+ G  G  G  G PG++GP+G
Sbjct: 739  GSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKG 798

Query: 846  AAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG--- 902
              G  G  G+ G PG PG  G  G+ G +G  G  G PG  G PGK G  G +G PG   
Sbjct: 799  ERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIV 858

Query: 903  ERGLP---GTAGGPGLKGNEGPSGPPGPAGSP---GERGAAGSGGPIGPPGRPGPQGPPG 956
            ++GLP   G  G PGL G +G  G PG AG P   G +G  GS G +G PG PG  G PG
Sbjct: 859  KKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPG 918

Query: 957  AAGEKGVPGEKGPIGPTGRDGV---------QGPVGLPGPAGPPG---VAGEDGDKGEVG 1004
              G KG+PG  G +GP+GR G           GPVG+P P  P     + G+ G +G  G
Sbjct: 919  TRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAG 978

Query: 1005 DPGQKGTKGNKGEHGPPGPPGPIGPVGQP----GAAGADGEPGARGPQGHFGAKGDEGTR 1060
              G  G +G+KGE G PGPPG  G  G P    G +G  G PG  G +G  G KG  G  
Sbjct: 979  SNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGIT 1038

Query: 1061 GFNGPPGPIGLQ------GLPGPSGEKGETGDVG-PMGPPGPPGPRGPAGPNGADGPQGP 1113
            GF G PG  G Q      GLPG SG  G  GD G  +   G PGP+G  G +G  G +G 
Sbjct: 1039 GFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGR 1098

Query: 1114 PGGVGNLGPPGEKGEPGE---SGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGP 1170
             G +GN+G PG KGE G+   SG  G+ G PG  G  G RGE G  G  G  G  GP G 
Sbjct: 1099 DGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGS 1158

Query: 1171 TGDDGPK------------GNPGPVGFPGDPGP--PGEGGPRGQDGAKGDRGEDG-EPGQ 1215
             G  GPK            G PG  G  G PGP   G  GP G  G KG++G  G   G 
Sbjct: 1159 PGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGA 1218

Query: 1216 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1275
            PG PG  G+ G  G  G +GPAG PG+ G        G PG  G PG  G  G  GPAG 
Sbjct: 1219 PGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGP 1278

Query: 1276 PGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL--- 1332
            PGP G     G  G  G PG  G  GP G  G PG  GL G+ G KG +G PG +G    
Sbjct: 1279 PGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGK 1338

Query: 1333 IGPPGE------QGEKGDRGLPGPQGSPGQ----------KGEMGIPGASGPIGPGGPPG 1376
            +GPPG+      +G+ G RG  G QG PGQ           G +G+PG  G  G  G PG
Sbjct: 1339 VGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPG 1398

Query: 1377 LPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1412
              GP G +G+KG  G  G  G  G+ GPPG  G PG
Sbjct: 1399 AQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPG 1434



 Score =  792 bits (2045), Expect = 0.0
 Identities = 545/1379 (39%), Positives = 637/1379 (46%), Gaps = 250/1379 (18%)

Query: 296  KGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPG------PVGDPGERGPPGRAG 349
            KG +G P  +     ++GP GP+G  G  G  G++G  G      P G  G++GP G  G
Sbjct: 46   KGARGRPGPIG----IQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPG 101

Query: 350  LPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYT 409
              G +G PG PG             G +GP         Q  +        G PGP GY 
Sbjct: 102  FLGINGIPGHPGQP-----------GPRGPPGLDGCNGTQGAV--------GFPGPDGY- 141

Query: 410  GRPGPLGQPGSPGLKGESGD-----------LGPQGPRGPQGLTGP---PGKAGRRGRAG 455
              PG LG PG PG KG  GD            G  G  G  G+TGP   PG  G  G AG
Sbjct: 142  --PGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAG 199

Query: 456  ADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGE----------R 505
              G +G PG PG  G  G  GL G  GEKG +GD G  G  GPP   GE          +
Sbjct: 200  PPGLQGPPGPPGPLGPDGNMGL-GFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKK 258

Query: 506  GDDGEIGPRGLPGESGPRGL--LGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPG 563
            G  GE GP+G PG SGP G   LG  G  G  G  G+ G+ GP+GP GS G Q   GPPG
Sbjct: 259  GSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQ---GPPG 315

Query: 564  QQGTPGTQGLPGPQGAIGPHGEKGPQGKPG-----------LPGMPGSDGPPGHPGKEGP 612
            QQG  GT G PG  G  G  G+KG  G PG           + G PG  G PG PG +G 
Sbjct: 316  QQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGD 375

Query: 613  PGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG------------------- 653
             G +G +GPSG  G     G  G  G  G  GLKG +G  G                   
Sbjct: 376  EGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPP 435

Query: 654  ------------------EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTG 695
                              E GFPG +G+ G KG+ G  G+ G  G    +G    TGP G
Sbjct: 436  GPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPG 495

Query: 696  DPGPP---GLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARG---LSGKSG 749
            +PGPP   GL+G  G  G  G  G  G QGP G+ G  G  G SG KG +G   LS   G
Sbjct: 496  EPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQG 555

Query: 750  PRGERGPTGPRGQRGPRGATGKSGAKGTSG-----GDGPHGPPGERGLPGPQGPNGFPGP 804
              G+RG +G +G RG  G  GK G  G  G     GDG  G PGE+GLPG  G  G PGP
Sbjct: 556  MPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGP 615

Query: 805  KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAA------GETGPMGERGH 858
             G PG    +GLPG PG RG  G +GK G PG  G+ G +G        G  GP G  G 
Sbjct: 616  PGLPG----NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGT 671

Query: 859  PGPPGPPGEQGLPGTAGK---EGTKGDPGPPGA---------PGKDGPAGLRGF---PGE 903
            PG PGP G +GLPGT G+    G+KG+PG PG          PG  G  GL GF   PG+
Sbjct: 672  PGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGK 731

Query: 904  RGLPGTAGGPGLKGNEGPSGP-----------------------PGPAGSPGERGAAGSG 940
             GLPG  G PGL G++G +G                         G +G PG +G  G  
Sbjct: 732  DGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKP 791

Query: 941  GPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDK 1000
            G +GP G  G  G PG  G+ G PG  GP G  G+ G+ G  G PG +G PG  G  G K
Sbjct: 792  GLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKK 851

Query: 1001 GEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1060
            G  G   +KG  G KG  G PG  G  G  G PG AG     G +G +G  G  G  G  
Sbjct: 852  GPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIP 911

Query: 1061 GFNGPPGPIGLQGLPGPS------------GEKGETGDVGPMGPPGP------------P 1096
            G  G PG  GL+G+PG +            GEKG+ G+ GP+G P P             
Sbjct: 912  GLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDK 971

Query: 1097 GPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG----ESGSPGIQGEPGVKGPRGERGE 1152
            G +G AG NG  GP+G  G  G  GPPG  G PG      G  G  G PG  G RG  G 
Sbjct: 972  GSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGL 1031

Query: 1153 KGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGE-------GGPRGQDGAKG 1205
            KG SG  G PG PG  G  G  G  G PG  G PG  G  G+        GP+GQ G  G
Sbjct: 1032 KGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESG 1091

Query: 1206 DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1265
             +G  G  G  G+ G  G  G  G +G  G  G PG+ G  G  G +G+PG  G+ G  G
Sbjct: 1092 FKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQG 1151

Query: 1266 PVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKG 1325
             +GP G  G  GP G  G PG  G  G PG  G  G PGP    G+PG  G  G KGEKG
Sbjct: 1152 AIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGP-SITGVPGPAGLPGPKGEKG 1210

Query: 1326 HPGL-IGLIGPPGEQGEKGDRGLPGPQ------------------------GSPGQKGEM 1360
            +PG+ IG  G PG +G+KGDRG PG Q                        G PG  GE 
Sbjct: 1211 YPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGER 1270

Query: 1361 GIPGASGPIGPGGP------------PGLPGPAGPKGAKGATGPGGPKGE---KGVQGPP 1405
            G PG +GP GP GP            PG+PGP GPKG +G  G  G  GE   KG++G P
Sbjct: 1271 GRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEP 1330

Query: 1406 GHPGPPGEVIQPLPIQMP-KKTRRSVDGSRLMQEDEA-IPTGGA---PGSPGGLEEIFG 1459
            G  G PG+V  P     P  K +    GS  +Q D    PT  A   P  P GL  I G
Sbjct: 1331 GFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDG 1389



 Score =  780 bits (2014), Expect = 0.0
 Identities = 541/1358 (39%), Positives = 639/1358 (47%), Gaps = 254/1358 (18%)

Query: 291  GPRGL---KGEKGEPAVLEPGML--VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPP 345
            GP GL   KG KG+P VL PG    ++G PG  G  G+ GP G  G PG VG  G   PP
Sbjct: 146  GPPGLPGQKGSKGDP-VLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAG---PP 201

Query: 346  GRAGLPGSDGAPGPPGTSLMLPFRFGSG-------GGDKGPVVAAQEAQAQAILQQARLA 398
            G  G PG  G  GP G ++ L F+   G        G  GP  +  E +      + +  
Sbjct: 202  GLQGPPGPPGPLGPDG-NMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGF-PKGKKG 259

Query: 399  LRGPPGPMGYTGRPGPLGQPG--SPGLKGESGDLG------PQGPRGPQGLTGPPGKAGR 450
             +G PGP G+ G  GP G PG  + G KGE G+ G      P+GP G +G+ GPPG+ G+
Sbjct: 260  SKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGK 319

Query: 451  RGRAGADGARGMPGDPGVKGDRGFDGL-----------------PGLPGEKGHRGDTGAQ 493
            +G  G  G  G  G  G KGD G  G                  PG+PG  G +GD G Q
Sbjct: 320  KGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQ 379

Query: 494  GLPGP---PGEDGERGDDGEIGPRGLPGESGPRG-----------------LLGPKGPPG 533
            GL GP   PG     G  G +GP+G PG  G +G                 L GP GPPG
Sbjct: 380  GLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPG 439

Query: 534  IPGPP-----------GVRGMDGPQGPKGSLG---------------------PQGEPGP 561
             P P            G  G+ G QGPKG+LG                     P GEPGP
Sbjct: 440  PPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGP 499

Query: 562  PGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGK------EGPPGT 615
            PG  G  G  GL G +G  G  G +GP G PGL G  G  GP G  G+      +G PG 
Sbjct: 500  PGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGD 559

Query: 616  KGNQGPSGPQGPLGYPGPRGVKGVDGI--------------RGLKGHKGEKGE------- 654
            +G+ G  G +G +G PG  GV G+ G+              +GL G  GEKG        
Sbjct: 560  RGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLP 619

Query: 655  -DGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPK------GRTGPTGDPGPPGLMGEKG 707
             +G PG  G  G+ GD+G+ G+PG +G  G +G        G  GP+G PG PG  G KG
Sbjct: 620  GNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKG 679

Query: 708  KLGVPGLPGYPGRQGPKGSLG---------FPGFPGASGEKGARGLSGKSGPRGERGPTG 758
              G+PG PG PG  G KG  G          PGFPG  GEKG  G  G  G  G  G  G
Sbjct: 680  SRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIG 739

Query: 759  PRGQRGPRGATGK--------SGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP--- 807
              G  G +GATG          G +G  G  G  G  G+ GLPG +G +G PG  GP   
Sbjct: 740  SPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGE 799

Query: 808  ---PGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGP--- 861
               PG PG+ G PG PG  G  G +GK+G PG PG  G  G  G+ G  G++G PG    
Sbjct: 800  RGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVK 859

Query: 862  PGPPGEQGLPGTAGKEGTKGDPGPPGAPG---------KDGPAGLRGFPGERGLPGTAGG 912
             G PG +GLPG  G  G KG PG PG  G         + G  G  GFPG  GLPG  G 
Sbjct: 860  KGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGT 919

Query: 913  PGLKG---NEGPSGPPGPAGSPGERGAAGSGGPIGPPG--RP-------GPQGPPGAAGE 960
             GLKG   + G  GP G AG+PGE+G  G+ GP+G P   RP       G +G  G+AG 
Sbjct: 920  RGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGS 979

Query: 961  KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPG----VAGEDGDKGEVGDPGQKGTKGNKG 1016
             G PG +G  G  GR G   P GLPG  G PG    V+G+ G  G +G  G  G KG+ G
Sbjct: 980  NGFPGPRGDKGEAGRPG---PPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSG 1036

Query: 1017 EHGPPGPPGPIGPVG---QPGAAGADGEPGARG-------------PQGHFGAKGDEGTR 1060
              G PG PG  G  G    PG  GA G PG +G             P+G  G  G +GT+
Sbjct: 1037 ITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTK 1096

Query: 1061 GFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNL 1120
            G +G  G IG  G  G  G+ G +GDVG  G PG PG  G  G  G  G  G  G +G L
Sbjct: 1097 GRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPL 1156

Query: 1121 GPPG---EKGEPGESGSPGIQGEPGVKG--------------PRGERGEKGESGQPG--- 1160
            G PG    KG PG  G  G+ G PG KG              P G  G KGE G PG   
Sbjct: 1157 GSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGI 1216

Query: 1161 -EPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPP------GEGGPRGQDGAKGDRGEDGEP 1213
              PG PG +G  GD G  G  GP G PG PG        G+ G  G+ G  G+RG  G  
Sbjct: 1217 GAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPA 1276

Query: 1214 GQPGSPGPTGENGP---------PGPLGKRGPAGSPGSEGRQGG---KGAKGDPGAIGAP 1261
            G PG PGP+   G          PGP G +G  G PG  G  G    KG +G+PG +G P
Sbjct: 1277 GPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTP 1336

Query: 1262 GKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAG----PPGPVGPPGL---PGL 1314
            GK   VGP G  G PG  G  G  GS G QG PG T  A     PPGP+G PG+   PGL
Sbjct: 1337 GK---VGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGL 1393

Query: 1315 RGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP 1374
             GD GA+G  G  G  GL   PG  G+ G  GLPGP   PG  G+ G+PG  GP G  G 
Sbjct: 1394 TGDPGAQGPVGLQGSKGL---PGIPGKDGPSGLPGP---PGALGDPGLPGLQGPPGFEGA 1447

Query: 1375 PGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1412
            PG  GP G  G  G +   G    K  Q     P P G
Sbjct: 1448 PGQQGPFGMPGMPGQSMRVGYTLVKHSQSEQVPPCPIG 1485



 Score =  690 bits (1780), Expect = 0.0
 Identities = 476/1268 (37%), Positives = 553/1268 (43%), Gaps = 304/1268 (23%)

Query: 482  GEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVR 541
            GEK +    G Q   G      E+G  G  GP G+ G +GP+G  G  G  G+ G  G  
Sbjct: 23   GEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFP 82

Query: 542  GMDGPQGPKGSLGPQ------------GEPGPPGQQGTPGTQGLPGPQGAIG-------- 581
            G+ GP GPKG  GP             G PG PG +G PG  G  G QGA+G        
Sbjct: 83   GLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYP 142

Query: 582  ---------------------PHGEKGPQGKPGLPGMPGSDGP---PGHPGKEGPPGTKG 617
                                 P   KG +G PGLPG+ G  GP   PG PG  GP G  G
Sbjct: 143  GLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPG 202

Query: 618  NQGPSGPQGP--------LGYPGPRGVKGVDGI-------------------RGLKGHKG 650
             QGP GP GP        LG+ G +GVKG  G+                   +G KG KG
Sbjct: 203  LQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKG 262

Query: 651  EKGEDGFPGFKGDIGVK--GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 708
            E G  GFPG  G  G    G  GE G  G +G  G  GP+G  G  G  GPPG  G+KG 
Sbjct: 263  EPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGT 322

Query: 709  LGVPGLPGYPGRQGPKGSLGF-----------------------PGFPGASGEKGARGLS 745
            LG PGL G+ G +G KG +G                        PG PG  G++G +GL 
Sbjct: 323  LGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLR 382

Query: 746  GK---------SGPRGERGPTGPRGQRGPRGATGKS--GAKGTSGGDGPHGPPGERGLPG 794
            G          SG  G  GP G  G +G +G  G++  GA G  G DG  GPPG  G P 
Sbjct: 383  GPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPS 442

Query: 795  P--------------------QGPNGF------------------------PGPKGPPGP 810
            P                    QGP G                         PG  GPPGP
Sbjct: 443  PEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGP 502

Query: 811  PGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE------RGHPGPPGP 864
             G  GLPG  G RG+ G  G  GP G PG+VGP G +G  G  GE      +G PG  G 
Sbjct: 503  WGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGD 562

Query: 865  PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGT------AGGPGLKGN 918
             G QG  G  G+ G  G PG PG PG  G  G +GFPGE+GLPG        G PGL GN
Sbjct: 563  SGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGG-QGFPGEKGLPGLPGEKGHPGPPGLPGN 621

Query: 919  EGPSGPPGPAGSPGERG---------------------AAGSGGPIGPPGRPGPQGPPGA 957
             G  G PGP G PG++G                       GS GP G PG PG  GP G+
Sbjct: 622  -GLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGS 680

Query: 958  AGEKGVPGEKGPIGPTGRDGVQGPV------GLPGPAGP------PGVAGEDGDKGEVGD 1005
             G  G PG+ G  G  G  G  G V      G PGP G       PG+ G+DG  G +G 
Sbjct: 681  RGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGS 740

Query: 1006 PGQKGTKGNKG-----EHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1060
            PG  G+KG  G     E+G PG  G  G  G  G  G  G PG +G  G  G  G +G R
Sbjct: 741  PGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGER 800

Query: 1061 GFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNL 1120
            G  G PG +G  G PG SG  G  G  G  G PG PG  G  G  G  G +GPPG +   
Sbjct: 801  GSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKK 860

Query: 1121 GPPGEKGEP---------GESGSPGIQGEPGVKGPRGERGEKGESGQPGEP--------- 1162
            G PG KG P         G  GSPG+ G P + GP+GE+G  G  G PG P         
Sbjct: 861  GLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTR 920

Query: 1163 ------------GPPGPKGPTGDDGPKGNPGPVGFP------------GDPGPPGEGGPR 1198
                        GP G  G  G+ G +GNPGPVG P            GD G  G  G  
Sbjct: 921  GLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSN 980

Query: 1199 GQDGAKGDRGEDGEPGQPGSPGP----------TGENGPPGPLGKRGP------------ 1236
            G  G +GD+GE G PG PG PG           +G+ GPPG +G RG             
Sbjct: 981  GFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGF 1040

Query: 1237 AGSPGSEGRQGGKGAKGDPGAIGAPGKTGP-------VGPAGPAGKPGPDGLR------- 1282
             G PG  G QG +G+ G PGA G PG  G         G  GP G+PG  G +       
Sbjct: 1041 PGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDG 1100

Query: 1283 -----GLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG 1337
                 G PG+ G+ G+ G +G  G PG  G PG+ G+RG+ G  G  GH G IG +G PG
Sbjct: 1101 LIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPG 1160

Query: 1338 EQGEKGDRGLPGPQGSPGQKGEMGIPGASGP--IGPGGPPGLPGPAGPK-------GAKG 1388
              G KG  G PG  G  G  G  G  G  GP   G  GP GLPGP G K       GA G
Sbjct: 1161 LIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAPG 1220

Query: 1389 ATGPGGPKGEK---GVQGPPGHPGPPGEVIQPLPIQMP-KKTRRSVDGSRLMQEDEAIPT 1444
              G  G KG++   G+QGP G PG PG  +  L    P    R  +DG R          
Sbjct: 1221 KPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGER-----GRPGP 1275

Query: 1445 GGAPGSPG 1452
             G PG PG
Sbjct: 1276 AGPPGPPG 1283



 Score =  544 bits (1402), Expect = e-154
 Identities = 382/975 (39%), Positives = 438/975 (44%), Gaps = 202/975 (20%)

Query: 672  EVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGV------PGLPGYPGRQGPKG 725
            E+   G +    P G +  +G        G  G  G +G+       G  G  G  G KG
Sbjct: 18   ELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKG 77

Query: 726  SLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHG 785
              GFPG  G  G KG +G  G  G  G  G  G  GQ GPRG  G  G  GT G  G  G
Sbjct: 78   ERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPG 137

Query: 786  PPGERGLPGPQG--------------PNGFPGPKGPPGPPGKDGL------PGHPGQRGE 825
            P G  GL GP G              P  F G KG PG PG DG+      PG PG  G 
Sbjct: 138  PDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGP 197

Query: 826  VGFQGKTGPPGPPGVVGPQ-----GAAGETGPMGERGHPGPPGP---------------- 864
             G  G  GPPGPPG +GP      G  GE G  G+ G PGP GP                
Sbjct: 198  AGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGK 257

Query: 865  ------PGEQGLP-----------GTAGKEGTKGDPGPPGAPGKDGP---AGLRGFPGER 904
                  PG +G P           GT G++G KG+ G PG PG  GP    G++G PG++
Sbjct: 258  KGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQ 317

Query: 905  GLPGTAGGPGL-----------------------------KGNEGPSGPPGPAGSPGERG 935
            G  GT G PGL                              GN G  G PG  G  G+ G
Sbjct: 318  GKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEG 377

Query: 936  AAGSGGPIGPPGRP---------GPQGPPGAAGEKGVPGEK--GPIGPTGRDGVQGPVGL 984
              G  GP G PG P         GPQG PG  G++G PG    G  G  GRDG+ GP G 
Sbjct: 378  IQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGP 437

Query: 985  PGPAGP--------------PGVAGEDGDKGEVGDPGQKGTKG---------NKGEHGPP 1021
            PGP  P              PG+ GE G KG +G  G KG  G         N G  G P
Sbjct: 438  PGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEP 497

Query: 1022 GPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIG------LQGLP 1075
            GPPGP G +G PG  GA G+ G+ G QG  GA G  G  G +GP G  G      +QG+P
Sbjct: 498  GPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMP 557

Query: 1076 GPSGEKGETGDVGPMGPPGPPGPRGPAGPNG--ADGPQGPPGGVGNLGPPGEKGEPGESG 1133
            G  G+ G  G  G +G PG  G  G  G  G   DG QG PG  G  G PGEKG PG  G
Sbjct: 558  GDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPG 617

Query: 1134 SPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT------GDDGPKGNPGPVGFPG 1187
             PG  G PG+ GPRG  G+KG+ G PG+ G PG KG T      G  GP G PG  GFPG
Sbjct: 618  LPG-NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPG 676

Query: 1188 DPGPPGEGGPRGQDGAKGDRGEDGEPG------QPGSPGPTGENGPPGPLGKRGPAGSP- 1240
              G  G  G  GQ G+ G +GE G PG       PG PGP GE G PG  G  G  G P 
Sbjct: 677  PKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPG 736

Query: 1241 --GSEGRQGGKGAKGD--------PGAIGAPGKTGPVGPAGPAGKP------------GP 1278
              GS G  G KGA GD        PG  G  G TG  G  G +G P            GP
Sbjct: 737  MIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGP 796

Query: 1279 DGLRGLPGSVGQQGRPGATGQAGP---------PGPVGPPGLPGLRGDAGAKGEKGHPGL 1329
             G RG PG+ GQ G+PG  G +GP         PG  G PG+ G  G  G +G+KG PG 
Sbjct: 797  KGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGS 856

Query: 1330 IGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIG----------PG--GPPGL 1377
            I   G PG +G  G+ GL G +GSPG  G  G+P  SGP G          PG  G PG+
Sbjct: 857  IVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGI 916

Query: 1378 PGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQ 1437
            PG  G KG  G+TG  GP G  G  G  G  G PG V  P P       RR +    L  
Sbjct: 917  PGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSP-------RRPMSNLWLKG 969

Query: 1438 EDEAIPTGGAPGSPG 1452
            +  +  + G+ G PG
Sbjct: 970  DKGSQGSAGSNGFPG 984



 Score =  437 bits (1125), Expect = e-122
 Identities = 287/727 (39%), Positives = 349/727 (48%), Gaps = 97/727 (13%)

Query: 263  PQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGML-VEGPPGPEGPA 321
            P+ +  +PG   ++ +     P    + GP G+KG+ G P    PG   + G PG +G  
Sbjct: 796  PKGERGSPGTPGQVGQ-----PGTPGSSGPYGIKGKSGLPGA--PGFPGISGHPGKKGTR 848

Query: 322  GLIGPP------------GIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFR 369
            G  GPP            G+ GNPG VG  G  G PG AGLP   G  G  G+   + F 
Sbjct: 849  GKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFP 908

Query: 370  FGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQP----------- 418
             G  G    P     +    +  +       G PG  G  G PGP+G P           
Sbjct: 909  -GIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWL 967

Query: 419  ----GSPGLKGESGDLGPQGPRGPQGLTGPPGKAGR----------RGRAGADGARGMPG 464
                GS G  G +G  GP+G +G  G  GPPG  G            G+ G  G  G+ G
Sbjct: 968  KGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRG 1027

Query: 465  DPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI-------GPRGLP 517
             PG+KG  G  G PG+PGE G +G  G+ GLPG  G  G +GD+G+        GP+G P
Sbjct: 1028 LPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQP 1087

Query: 518  GESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGP- 576
            GESG +G  G  G  G  G PG +G DG  G  G +G  G PG PG  G  G  GLPG  
Sbjct: 1088 GESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSS 1147

Query: 577  --QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS--GPQGPLGYPG 632
              QGAIGP G  G  G  G PG PG  G  G PG +   GT G  GPS  G  GP G PG
Sbjct: 1148 GHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTK---GTHGTPGPSITGVPGPAGLPG 1204

Query: 633  PRGVKGVDGI----RGLKGHKGEKGEDGFPGFKGDIGVKGDRG------EVGVPGSRGED 682
            P+G KG  GI     G  G +G+KG+ GFPG +G  G+ G  G        G PG  G  
Sbjct: 1205 PKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRP 1264

Query: 683  GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGAR 742
            G +G +GR GP G PGPPG    +G  G PG PG PG +GPKG  G PGF G  GE G +
Sbjct: 1265 GLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLK 1324

Query: 743  GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 802
            G+ G+ G  G  G  GP G  G  G  GK+G +G+S   G  G PG+   P  +     P
Sbjct: 1325 GMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSS---GLQGDPGQ--TPTAEAVQVPP 1379

Query: 803  GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 862
            GP G PG  G  GL G PG +G VG QG  G PG PG  GP G             PGPP
Sbjct: 1380 GPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGL------------PGPP 1427

Query: 863  GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPS 922
            G  G+ GLP      G +G PG  GAPG+ GP G+ G PG+       G   +K ++   
Sbjct: 1428 GALGDPGLP------GLQGPPGFEGAPGQQGPFGMPGMPGQ---SMRVGYTLVKHSQSEQ 1478

Query: 923  GPPGPAG 929
             PP P G
Sbjct: 1479 VPPCPIG 1485



 Score =  105 bits (262), Expect = 4e-22
 Identities = 73/191 (38%), Positives = 86/191 (45%), Gaps = 11/191 (5%)

Query: 1264 TGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1323
            T  +  AG      P G +   GS       GA G+ GP G  GP G  G  G  G  G 
Sbjct: 16   TEELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGL 75

Query: 1324 KGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGP 1383
            KG  G  GL+GP G +G+KG  G+      PG  G  GIPG  G  GP GPPGL    G 
Sbjct: 76   KGERGFPGLLGPYGPKGDKGPMGV------PGFLGINGIPGHPGQPGPRGPPGLD---GC 126

Query: 1384 KGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP 1443
             G +GA G  GP G  G+ GPPG PG  G   +  P+  P   +       L   D    
Sbjct: 127  NGTQGAVGFPGPDGYPGLLGPPGLPGQKGS--KGDPVLAPGSFKGMKGDPGLPGLDGITG 184

Query: 1444 TGGAPGSPGGL 1454
              GAPG PG +
Sbjct: 185  PQGAPGFPGAV 195


>gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo
            sapiens]
          Length = 1690

 Score =  805 bits (2078), Expect = 0.0
 Identities = 548/1395 (39%), Positives = 640/1395 (45%), Gaps = 270/1395 (19%)

Query: 291  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPG---- 346
            G  GLKGE+G P +L P     GP G +GP G+ G  GI G PG  G PG RGPPG    
Sbjct: 70   GLSGLKGERGFPGLLGP----YGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGC 125

Query: 347  -----RAGLPGSDGAPG---PPGTS---------LMLPFRFGSGGGDKG-PVVAAQEAQA 388
                   G PG DG PG   PPG           ++ P  F    GD G P +       
Sbjct: 126  NGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQ 185

Query: 389  QAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGL-----KGESGDLGPQGPRGPQGLTG 443
             A      +   GPPG  G  G PGPLG  G+ GL     KG  GD+G  GP GP   TG
Sbjct: 186  GAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTG 245

Query: 444  -------PPGKAGRRGRAGADGARGMPGDPGV--------KGDRGFDGLPGLPGEKGHRG 488
                   P GK G +G  G  G  G+ G PG         KG++G  G+PGLPG +G  G
Sbjct: 246  ELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMG 305

Query: 489  DTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPK--------------GPPGI 534
              G QG PG  G+ G  G  G  G +G+ G+ G  GL GP               G PG+
Sbjct: 306  SEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGV 365

Query: 535  PGPPGVRGMDGPQGPKG---------------SLGPQGEPGPPGQQGTPGT--------- 570
            PG PG++G +G QG +G               +LGPQG PG  G QG PG          
Sbjct: 366  PGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLP 425

Query: 571  --QGLPGPQGAIGP--------------------HGEKGPQGKPGLPGMPGSDG------ 602
               GLPGP G  GP                     GE+GP+G  GL G+ G  G      
Sbjct: 426  GRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDG 485

Query: 603  ------PPGHPGKEGP---------PGTKGNQGPSGPQGPLGYPG---------PRGVKG 638
                  PPG PG  GP          G +G++G  G QGP G PG         P+G KG
Sbjct: 486  GVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKG 545

Query: 639  V---------------DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDG 683
                             G +G +G  GE G+DG PG  G  G+ GD G+ G PG +G  G
Sbjct: 546  EPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQ-GFPGEKGLPG 604

Query: 684  PEGPKGRTGPTGDPG--------PPGLMGEKGKLGVPGLPGYPGRQG---------PKGS 726
              G KG  GP G PG        P GL G+KGK G+PG  G PG +G           G 
Sbjct: 605  LPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGP 664

Query: 727  LGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRG------------PRGATGKSGA 774
             GFPG PG  G KG+RGL G  G  G  G  G  G  G            PRG  G  G 
Sbjct: 665  SGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGF 724

Query: 775  KGTSGGDGPHGPPGERGLPGPQGPNG--FPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKT 832
             G  G DG  G  G  GLPG +G  G  F    G PG  G  GL GH G  G+ G  G  
Sbjct: 725  PGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLK 784

Query: 833  GPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKD 892
            G  G PG++GP+G  G  G  G+ G PG PG  G  G+ G +G  G  G PG  G PGK 
Sbjct: 785  GVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKK 844

Query: 893  GPAGLRGFPG---ERGLPGTAG---GPGLKGNEGPSGPPGPAGSP---GERGAAGSGGPI 943
            G  G +G PG   ++GLPG  G    PGL G +G  G PG AG P   G +G  GS G +
Sbjct: 845  GTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFV 904

Query: 944  GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQG---------PVGLPGPAGPPG-- 992
            G PG PG  G PG  G KG+PG  G +GP+GR G  G         PVG+P P  P    
Sbjct: 905  GFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNL 964

Query: 993  -VAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPG----AAGADGEPGARGP 1047
             + G+ G +G  G  G  G +G+KGE G PGPPG  G  G PG     +G  G PG  G 
Sbjct: 965  WLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGI 1024

Query: 1048 QGHFGAKGDEGTRGFNGPPGPIGLQG------LPGPSGEKGETGDVGP-MGPPGPPGPRG 1100
            +G  G KG  G  GF G PG  G QG      LPG SG  G  GD G  +   G PGP+G
Sbjct: 1025 RGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKG 1084

Query: 1101 PAGPNGADGPQGPPGGVGNLGPPGEKGEPGE---SGSPGIQGEPGVKGPRGERGEKGESG 1157
              G +G  G +G  G +GN+G PG KGE G+   SG  G+ G PG  G  G RGE G  G
Sbjct: 1085 QPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPG 1144

Query: 1158 QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAK-----------GD 1206
              G  G  GP G  G  GPKG PG  G  G  G PG  G  G  G             G 
Sbjct: 1145 SSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGP 1204

Query: 1207 RGEDGEPG----QPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPG 1262
            +GE G PG     PG PG  G+ G  G  G +GPAG PG+ G        G PG  G PG
Sbjct: 1205 KGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPG 1264

Query: 1263 KTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKG 1322
              G  G  GPAG PGP G     G  G  G PG  G  GP G  G PG  GL G+ G KG
Sbjct: 1265 LDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKG 1324

Query: 1323 EKGHPGLIGL---IGPPGEQGEKGDRGLPGPQGSPGQKGE-------------------- 1359
             +G PG +G    +GPPG+ G  G +G  GP+GS G +G+                    
Sbjct: 1325 MRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLP 1384

Query: 1360 --------MGIPGASGPI---GPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHP 1408
                     G PGA GP+   G  G PG+PG  GP G  G  G  G  G  G+QGPPG  
Sbjct: 1385 GIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFE 1444

Query: 1409 GPPGEVIQPLPIQMP 1423
            G PG   Q  P  MP
Sbjct: 1445 GAPG---QQGPFGMP 1456



 Score =  800 bits (2066), Expect = 0.0
 Identities = 542/1356 (39%), Positives = 635/1356 (46%), Gaps = 242/1356 (17%)

Query: 290  HGPRGLKGEKGEPAVLE----PGMLVEGPPGPEGPAGLIGPPGIQGN---PGPVGDPGER 342
            +GP+G KG  G P  L     PG    G PGP GP GL G  G QG    PGP G PG  
Sbjct: 87   YGPKGDKGPMGVPGFLGINGIPGH--PGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLL 144

Query: 343  GPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKG-PVVAAQEAQAQAILQQARLALRG 401
            GPP   GLPG  G+ G P   ++ P  F    GD G P +        A      +   G
Sbjct: 145  GPP---GLPGQKGSKGDP---VLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAG 198

Query: 402  PPGPMGYTGRPGPLGQPGSPGL-----KGESGDLGPQGPRGPQGLTG-------PPGKAG 449
            PPG  G  G PGPLG  G+ GL     KG  GD+G  GP GP   TG       P GK G
Sbjct: 199  PPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKG 258

Query: 450  RRGRAGADGARGMPGDPGV--------KGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGE 501
             +G  G  G  G+ G PG         KG++G  G+PGLPG +G  G  G QG PG  G+
Sbjct: 259  SKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGK 318

Query: 502  DGERGDDGEIGPRGLPGESGPRGLLGP--------------KGPPGIPGPPGVRGMDGPQ 547
             G  G  G  G +G+ G+ G  GL GP               G PG+PG PG++G +G Q
Sbjct: 319  KGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQ 378

Query: 548  GPK---------------GSLGPQGEPGPPGQQGT-----------PGTQGLPGPQGAIG 581
            G +               G+LGPQG PG  G QG            PG  GLPGP G  G
Sbjct: 379  GLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPG 438

Query: 582  P--------------------HGEKGPQGKPGLPGMPG------------SDGPPGHPGK 609
            P                     GE+GP+G  GL G+ G            + GPPG PG 
Sbjct: 439  PPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGP 498

Query: 610  EGP---------PGTKGNQGPSGPQGPLGYP---------GPRGVKGV------------ 639
             GP          G +G++G  G QGP G P         GP+G KG             
Sbjct: 499  PGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGD 558

Query: 640  ---DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGP--- 693
                G +G +G  GE G+DG PG  G  G+ GD G+ G PG +G  G  G KG  GP   
Sbjct: 559  RGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQ-GFPGEKGLPGLPGEKGHPGPPGL 617

Query: 694  -----TGDPGPPGLMGEKGKLGVPGLPGYPGRQ---------GPKGSLGFPGFPGASGEK 739
                  G PGP GL G+KGK G+PG  G PG +         G  G  GFPG PG  G K
Sbjct: 618  PGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPK 677

Query: 740  GARGLSGKSGPRGERGPTGPRGQ------------RGPRGATGKSGAKGTSGGDGPHGPP 787
            G+RGL G  G  G  G  G  G              GPRG  G  G  G  G DG  G  
Sbjct: 678  GSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMI 737

Query: 788  GERGLPGPQGPNG--FPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQG 845
            G  GLPG +G  G  F    G PG  G  GL GH G  G+ G  G  G  G PG++GP+G
Sbjct: 738  GSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKG 797

Query: 846  AAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG--- 902
              G  G  G+ G PG PG  G  G+ G +G  G  G PG  G PGK G  G +G PG   
Sbjct: 798  ERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIV 857

Query: 903  ERGLP---GTAGGPGLKGNEGPSGPPGPAGSP---GERGAAGSGGPIGPPGRPGPQGPPG 956
            ++GLP   G  G PGL G +G  G PG AG P   G +G  GS G +G PG PG  G PG
Sbjct: 858  KKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPG 917

Query: 957  AAGEKGVPGEKGPIGPTGRDGV---------QGPVGLPGPAGPPG---VAGEDGDKGEVG 1004
              G KG+PG  G +GP+GR G           GPVG+P P  P     + G+ G +G  G
Sbjct: 918  TRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAG 977

Query: 1005 DPGQKGTKGNKGEHGPPGPPGPIGPVGQP----GAAGADGEPGARGPQGHFGAKGDEGTR 1060
              G  G +G+KGE G PGPPG  G  G P    G +G  G PG  G +G  G KG  G  
Sbjct: 978  SNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGIT 1037

Query: 1061 GFNGPPGPIGLQ------GLPGPSGEKGETGDVG-PMGPPGPPGPRGPAGPNGADGPQGP 1113
            GF G PG  G Q      GLPG SG  G  GD G  +   G PGP+G  G +G  G +G 
Sbjct: 1038 GFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGR 1097

Query: 1114 PGGVGNLGPPGEKGEPGE---SGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGP 1170
             G +GN+G PG KGE G+   SG  G+ G PG  G  G RGE G  G  G  G  GP G 
Sbjct: 1098 DGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGS 1157

Query: 1171 TGDDGPK------------GNPGPVGFPGDPGP--PGEGGPRGQDGAKGDRGEDG-EPGQ 1215
             G  GPK            G PG  G  G PGP   G  GP G  G KG++G  G   G 
Sbjct: 1158 PGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGA 1217

Query: 1216 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1275
            PG PG  G+ G  G  G +GPAG PG+ G        G PG  G PG  G  G  GPAG 
Sbjct: 1218 PGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGP 1277

Query: 1276 PGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL--- 1332
            PGP G     G  G  G PG  G  GP G  G PG  GL G+ G KG +G PG +G    
Sbjct: 1278 PGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGK 1337

Query: 1333 IGPPGE------QGEKGDRGLPGPQGSPGQ----------KGEMGIPGASGPIGPGGPPG 1376
            +GPPG+      +G+ G RG  G QG PGQ           G +G+PG  G  G  G PG
Sbjct: 1338 VGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPG 1397

Query: 1377 LPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1412
              GP G +G+KG  G  G  G  G+ GPPG  G PG
Sbjct: 1398 AQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPG 1433



 Score =  792 bits (2045), Expect = 0.0
 Identities = 545/1379 (39%), Positives = 637/1379 (46%), Gaps = 250/1379 (18%)

Query: 296  KGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPG------PVGDPGERGPPGRAG 349
            KG +G P  +     ++GP GP+G  G  G  G++G  G      P G  G++GP G  G
Sbjct: 45   KGARGRPGPIG----IQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPG 100

Query: 350  LPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYT 409
              G +G PG PG             G +GP         Q  +        G PGP GY 
Sbjct: 101  FLGINGIPGHPGQP-----------GPRGPPGLDGCNGTQGAV--------GFPGPDGY- 140

Query: 410  GRPGPLGQPGSPGLKGESGD-----------LGPQGPRGPQGLTGP---PGKAGRRGRAG 455
              PG LG PG PG KG  GD            G  G  G  G+TGP   PG  G  G AG
Sbjct: 141  --PGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAG 198

Query: 456  ADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGE----------R 505
              G +G PG PG  G  G  GL G  GEKG +GD G  G  GPP   GE          +
Sbjct: 199  PPGLQGPPGPPGPLGPDGNMGL-GFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKK 257

Query: 506  GDDGEIGPRGLPGESGPRGL--LGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPG 563
            G  GE GP+G PG SGP G   LG  G  G  G  G+ G+ GP+GP GS G Q   GPPG
Sbjct: 258  GSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQ---GPPG 314

Query: 564  QQGTPGTQGLPGPQGAIGPHGEKGPQGKPG-----------LPGMPGSDGPPGHPGKEGP 612
            QQG  GT G PG  G  G  G+KG  G PG           + G PG  G PG PG +G 
Sbjct: 315  QQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGD 374

Query: 613  PGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG------------------- 653
             G +G +GPSG  G     G  G  G  G  GLKG +G  G                   
Sbjct: 375  EGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPP 434

Query: 654  ------------------EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTG 695
                              E GFPG +G+ G KG+ G  G+ G  G    +G    TGP G
Sbjct: 435  GPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPG 494

Query: 696  DPGPP---GLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARG---LSGKSG 749
            +PGPP   GL+G  G  G  G  G  G QGP G+ G  G  G SG KG +G   LS   G
Sbjct: 495  EPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQG 554

Query: 750  PRGERGPTGPRGQRGPRGATGKSGAKGTSG-----GDGPHGPPGERGLPGPQGPNGFPGP 804
              G+RG +G +G RG  G  GK G  G  G     GDG  G PGE+GLPG  G  G PGP
Sbjct: 555  MPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGP 614

Query: 805  KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAA------GETGPMGERGH 858
             G PG    +GLPG PG RG  G +GK G PG  G+ G +G        G  GP G  G 
Sbjct: 615  PGLPG----NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGT 670

Query: 859  PGPPGPPGEQGLPGTAGK---EGTKGDPGPPGA---------PGKDGPAGLRGF---PGE 903
            PG PGP G +GLPGT G+    G+KG+PG PG          PG  G  GL GF   PG+
Sbjct: 671  PGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGK 730

Query: 904  RGLPGTAGGPGLKGNEGPSGP-----------------------PGPAGSPGERGAAGSG 940
             GLPG  G PGL G++G +G                         G +G PG +G  G  
Sbjct: 731  DGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKP 790

Query: 941  GPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDK 1000
            G +GP G  G  G PG  G+ G PG  GP G  G+ G+ G  G PG +G PG  G  G K
Sbjct: 791  GLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKK 850

Query: 1001 GEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1060
            G  G   +KG  G KG  G PG  G  G  G PG AG     G +G +G  G  G  G  
Sbjct: 851  GPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIP 910

Query: 1061 GFNGPPGPIGLQGLPGPS------------GEKGETGDVGPMGPPGP------------P 1096
            G  G PG  GL+G+PG +            GEKG+ G+ GP+G P P             
Sbjct: 911  GLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDK 970

Query: 1097 GPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG----ESGSPGIQGEPGVKGPRGERGE 1152
            G +G AG NG  GP+G  G  G  GPPG  G PG      G  G  G PG  G RG  G 
Sbjct: 971  GSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGL 1030

Query: 1153 KGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGE-------GGPRGQDGAKG 1205
            KG SG  G PG PG  G  G  G  G PG  G PG  G  G+        GP+GQ G  G
Sbjct: 1031 KGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESG 1090

Query: 1206 DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1265
             +G  G  G  G+ G  G  G  G +G  G  G PG+ G  G  G +G+PG  G+ G  G
Sbjct: 1091 FKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQG 1150

Query: 1266 PVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKG 1325
             +GP G  G  GP G  G PG  G  G PG  G  G PGP    G+PG  G  G KGEKG
Sbjct: 1151 AIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGP-SITGVPGPAGLPGPKGEKG 1209

Query: 1326 HPGL-IGLIGPPGEQGEKGDRGLPGPQ------------------------GSPGQKGEM 1360
            +PG+ IG  G PG +G+KGDRG PG Q                        G PG  GE 
Sbjct: 1210 YPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGER 1269

Query: 1361 GIPGASGPIGPGGP------------PGLPGPAGPKGAKGATGPGGPKGE---KGVQGPP 1405
            G PG +GP GP GP            PG+PGP GPKG +G  G  G  GE   KG++G P
Sbjct: 1270 GRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEP 1329

Query: 1406 GHPGPPGEVIQPLPIQMP-KKTRRSVDGSRLMQEDEA-IPTGGA---PGSPGGLEEIFG 1459
            G  G PG+V  P     P  K +    GS  +Q D    PT  A   P  P GL  I G
Sbjct: 1330 GFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDG 1388



 Score =  780 bits (2014), Expect = 0.0
 Identities = 541/1358 (39%), Positives = 639/1358 (47%), Gaps = 254/1358 (18%)

Query: 291  GPRGL---KGEKGEPAVLEPGML--VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPP 345
            GP GL   KG KG+P VL PG    ++G PG  G  G+ GP G  G PG VG  G   PP
Sbjct: 145  GPPGLPGQKGSKGDP-VLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAG---PP 200

Query: 346  GRAGLPGSDGAPGPPGTSLMLPFRFGSG-------GGDKGPVVAAQEAQAQAILQQARLA 398
            G  G PG  G  GP G ++ L F+   G        G  GP  +  E +      + +  
Sbjct: 201  GLQGPPGPPGPLGPDG-NMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGF-PKGKKG 258

Query: 399  LRGPPGPMGYTGRPGPLGQPG--SPGLKGESGDLG------PQGPRGPQGLTGPPGKAGR 450
             +G PGP G+ G  GP G PG  + G KGE G+ G      P+GP G +G+ GPPG+ G+
Sbjct: 259  SKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGK 318

Query: 451  RGRAGADGARGMPGDPGVKGDRGFDGL-----------------PGLPGEKGHRGDTGAQ 493
            +G  G  G  G  G  G KGD G  G                  PG+PG  G +GD G Q
Sbjct: 319  KGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQ 378

Query: 494  GLPGP---PGEDGERGDDGEIGPRGLPGESGPRG-----------------LLGPKGPPG 533
            GL GP   PG     G  G +GP+G PG  G +G                 L GP GPPG
Sbjct: 379  GLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPG 438

Query: 534  IPGPP-----------GVRGMDGPQGPKGSLG---------------------PQGEPGP 561
             P P            G  G+ G QGPKG+LG                     P GEPGP
Sbjct: 439  PPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGP 498

Query: 562  PGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGK------EGPPGT 615
            PG  G  G  GL G +G  G  G +GP G PGL G  G  GP G  G+      +G PG 
Sbjct: 499  PGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGD 558

Query: 616  KGNQGPSGPQGPLGYPGPRGVKGVDGI--------------RGLKGHKGEKGE------- 654
            +G+ G  G +G +G PG  GV G+ G+              +GL G  GEKG        
Sbjct: 559  RGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLP 618

Query: 655  -DGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPK------GRTGPTGDPGPPGLMGEKG 707
             +G PG  G  G+ GD+G+ G+PG +G  G +G        G  GP+G PG PG  G KG
Sbjct: 619  GNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKG 678

Query: 708  KLGVPGLPGYPGRQGPKGSLG---------FPGFPGASGEKGARGLSGKSGPRGERGPTG 758
              G+PG PG PG  G KG  G          PGFPG  GEKG  G  G  G  G  G  G
Sbjct: 679  SRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIG 738

Query: 759  PRGQRGPRGATGK--------SGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP--- 807
              G  G +GATG          G +G  G  G  G  G+ GLPG +G +G PG  GP   
Sbjct: 739  SPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGE 798

Query: 808  ---PGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGP--- 861
               PG PG+ G PG PG  G  G +GK+G PG PG  G  G  G+ G  G++G PG    
Sbjct: 799  RGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVK 858

Query: 862  PGPPGEQGLPGTAGKEGTKGDPGPPGAPG---------KDGPAGLRGFPGERGLPGTAGG 912
             G PG +GLPG  G  G KG PG PG  G         + G  G  GFPG  GLPG  G 
Sbjct: 859  KGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGT 918

Query: 913  PGLKG---NEGPSGPPGPAGSPGERGAAGSGGPIGPPG--RP-------GPQGPPGAAGE 960
             GLKG   + G  GP G AG+PGE+G  G+ GP+G P   RP       G +G  G+AG 
Sbjct: 919  RGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGS 978

Query: 961  KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPG----VAGEDGDKGEVGDPGQKGTKGNKG 1016
             G PG +G  G  GR G   P GLPG  G PG    V+G+ G  G +G  G  G KG+ G
Sbjct: 979  NGFPGPRGDKGEAGRPG---PPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSG 1035

Query: 1017 EHGPPGPPGPIGPVG---QPGAAGADGEPGARG-------------PQGHFGAKGDEGTR 1060
              G PG PG  G  G    PG  GA G PG +G             P+G  G  G +GT+
Sbjct: 1036 ITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTK 1095

Query: 1061 GFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNL 1120
            G +G  G IG  G  G  G+ G +GDVG  G PG PG  G  G  G  G  G  G +G L
Sbjct: 1096 GRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPL 1155

Query: 1121 GPPG---EKGEPGESGSPGIQGEPGVKG--------------PRGERGEKGESGQPG--- 1160
            G PG    KG PG  G  G+ G PG KG              P G  G KGE G PG   
Sbjct: 1156 GSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGI 1215

Query: 1161 -EPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPP------GEGGPRGQDGAKGDRGEDGEP 1213
              PG PG +G  GD G  G  GP G PG PG        G+ G  G+ G  G+RG  G  
Sbjct: 1216 GAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPA 1275

Query: 1214 GQPGSPGPTGENGP---------PGPLGKRGPAGSPGSEGRQGG---KGAKGDPGAIGAP 1261
            G PG PGP+   G          PGP G +G  G PG  G  G    KG +G+PG +G P
Sbjct: 1276 GPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTP 1335

Query: 1262 GKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAG----PPGPVGPPGL---PGL 1314
            GK   VGP G  G PG  G  G  GS G QG PG T  A     PPGP+G PG+   PGL
Sbjct: 1336 GK---VGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGL 1392

Query: 1315 RGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP 1374
             GD GA+G  G  G  GL   PG  G+ G  GLPGP   PG  G+ G+PG  GP G  G 
Sbjct: 1393 TGDPGAQGPVGLQGSKGL---PGIPGKDGPSGLPGP---PGALGDPGLPGLQGPPGFEGA 1446

Query: 1375 PGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1412
            PG  GP G  G  G +   G    K  Q     P P G
Sbjct: 1447 PGQQGPFGMPGMPGQSMRVGYTLVKHSQSEQVPPCPIG 1484



 Score =  690 bits (1780), Expect = 0.0
 Identities = 476/1268 (37%), Positives = 553/1268 (43%), Gaps = 304/1268 (23%)

Query: 482  GEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVR 541
            GEK +    G Q   G      E+G  G  GP G+ G +GP+G  G  G  G+ G  G  
Sbjct: 22   GEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFP 81

Query: 542  GMDGPQGPKGSLGPQ------------GEPGPPGQQGTPGTQGLPGPQGAIG-------- 581
            G+ GP GPKG  GP             G PG PG +G PG  G  G QGA+G        
Sbjct: 82   GLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYP 141

Query: 582  ---------------------PHGEKGPQGKPGLPGMPGSDGP---PGHPGKEGPPGTKG 617
                                 P   KG +G PGLPG+ G  GP   PG PG  GP G  G
Sbjct: 142  GLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPG 201

Query: 618  NQGPSGPQGP--------LGYPGPRGVKGVDGI-------------------RGLKGHKG 650
             QGP GP GP        LG+ G +GVKG  G+                   +G KG KG
Sbjct: 202  LQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKG 261

Query: 651  EKGEDGFPGFKGDIGVK--GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 708
            E G  GFPG  G  G    G  GE G  G +G  G  GP+G  G  G  GPPG  G+KG 
Sbjct: 262  EPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGT 321

Query: 709  LGVPGLPGYPGRQGPKGSLGF-----------------------PGFPGASGEKGARGLS 745
            LG PGL G+ G +G KG +G                        PG PG  G++G +GL 
Sbjct: 322  LGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLR 381

Query: 746  GK---------SGPRGERGPTGPRGQRGPRGATGKS--GAKGTSGGDGPHGPPGERGLPG 794
            G          SG  G  GP G  G +G +G  G++  GA G  G DG  GPPG  G P 
Sbjct: 382  GPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPS 441

Query: 795  P--------------------QGPNGF------------------------PGPKGPPGP 810
            P                    QGP G                         PG  GPPGP
Sbjct: 442  PEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGP 501

Query: 811  PGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE------RGHPGPPGP 864
             G  GLPG  G RG+ G  G  GP G PG+VGP G +G  G  GE      +G PG  G 
Sbjct: 502  WGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGD 561

Query: 865  PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGT------AGGPGLKGN 918
             G QG  G  G+ G  G PG PG PG  G  G +GFPGE+GLPG        G PGL GN
Sbjct: 562  SGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGG-QGFPGEKGLPGLPGEKGHPGPPGLPGN 620

Query: 919  EGPSGPPGPAGSPGERG---------------------AAGSGGPIGPPGRPGPQGPPGA 957
             G  G PGP G PG++G                       GS GP G PG PG  GP G+
Sbjct: 621  -GLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGS 679

Query: 958  AGEKGVPGEKGPIGPTGRDGVQGPV------GLPGPAGP------PGVAGEDGDKGEVGD 1005
             G  G PG+ G  G  G  G  G V      G PGP G       PG+ G+DG  G +G 
Sbjct: 680  RGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGS 739

Query: 1006 PGQKGTKGNKG-----EHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1060
            PG  G+KG  G     E+G PG  G  G  G  G  G  G PG +G  G  G  G +G R
Sbjct: 740  PGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGER 799

Query: 1061 GFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNL 1120
            G  G PG +G  G PG SG  G  G  G  G PG PG  G  G  G  G +GPPG +   
Sbjct: 800  GSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKK 859

Query: 1121 GPPGEKGEP---------GESGSPGIQGEPGVKGPRGERGEKGESGQPGEP--------- 1162
            G PG KG P         G  GSPG+ G P + GP+GE+G  G  G PG P         
Sbjct: 860  GLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTR 919

Query: 1163 ------------GPPGPKGPTGDDGPKGNPGPVGFP------------GDPGPPGEGGPR 1198
                        GP G  G  G+ G +GNPGPVG P            GD G  G  G  
Sbjct: 920  GLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSN 979

Query: 1199 GQDGAKGDRGEDGEPGQPGSPGP----------TGENGPPGPLGKRGP------------ 1236
            G  G +GD+GE G PG PG PG           +G+ GPPG +G RG             
Sbjct: 980  GFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGF 1039

Query: 1237 AGSPGSEGRQGGKGAKGDPGAIGAPGKTGP-------VGPAGPAGKPGPDGLR------- 1282
             G PG  G QG +G+ G PGA G PG  G         G  GP G+PG  G +       
Sbjct: 1040 PGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDG 1099

Query: 1283 -----GLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG 1337
                 G PG+ G+ G+ G +G  G PG  G PG+ G+RG+ G  G  GH G IG +G PG
Sbjct: 1100 LIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPG 1159

Query: 1338 EQGEKGDRGLPGPQGSPGQKGEMGIPGASGP--IGPGGPPGLPGPAGPK-------GAKG 1388
              G KG  G PG  G  G  G  G  G  GP   G  GP GLPGP G K       GA G
Sbjct: 1160 LIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAPG 1219

Query: 1389 ATGPGGPKGEK---GVQGPPGHPGPPGEVIQPLPIQMP-KKTRRSVDGSRLMQEDEAIPT 1444
              G  G KG++   G+QGP G PG PG  +  L    P    R  +DG R          
Sbjct: 1220 KPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGER-----GRPGP 1274

Query: 1445 GGAPGSPG 1452
             G PG PG
Sbjct: 1275 AGPPGPPG 1282



 Score =  544 bits (1402), Expect = e-154
 Identities = 382/975 (39%), Positives = 438/975 (44%), Gaps = 202/975 (20%)

Query: 672  EVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGV------PGLPGYPGRQGPKG 725
            E+   G +    P G +  +G        G  G  G +G+       G  G  G  G KG
Sbjct: 17   ELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKG 76

Query: 726  SLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHG 785
              GFPG  G  G KG +G  G  G  G  G  G  GQ GPRG  G  G  GT G  G  G
Sbjct: 77   ERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPG 136

Query: 786  PPGERGLPGPQG--------------PNGFPGPKGPPGPPGKDGL------PGHPGQRGE 825
            P G  GL GP G              P  F G KG PG PG DG+      PG PG  G 
Sbjct: 137  PDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGP 196

Query: 826  VGFQGKTGPPGPPGVVGPQ-----GAAGETGPMGERGHPGPPGP---------------- 864
             G  G  GPPGPPG +GP      G  GE G  G+ G PGP GP                
Sbjct: 197  AGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGK 256

Query: 865  ------PGEQGLP-----------GTAGKEGTKGDPGPPGAPGKDGP---AGLRGFPGER 904
                  PG +G P           GT G++G KG+ G PG PG  GP    G++G PG++
Sbjct: 257  KGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQ 316

Query: 905  GLPGTAGGPGL-----------------------------KGNEGPSGPPGPAGSPGERG 935
            G  GT G PGL                              GN G  G PG  G  G+ G
Sbjct: 317  GKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEG 376

Query: 936  AAGSGGPIGPPGRP---------GPQGPPGAAGEKGVPGEK--GPIGPTGRDGVQGPVGL 984
              G  GP G PG P         GPQG PG  G++G PG    G  G  GRDG+ GP G 
Sbjct: 377  IQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGP 436

Query: 985  PGPAGP--------------PGVAGEDGDKGEVGDPGQKGTKG---------NKGEHGPP 1021
            PGP  P              PG+ GE G KG +G  G KG  G         N G  G P
Sbjct: 437  PGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEP 496

Query: 1022 GPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIG------LQGLP 1075
            GPPGP G +G PG  GA G+ G+ G QG  GA G  G  G +GP G  G      +QG+P
Sbjct: 497  GPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMP 556

Query: 1076 GPSGEKGETGDVGPMGPPGPPGPRGPAGPNG--ADGPQGPPGGVGNLGPPGEKGEPGESG 1133
            G  G+ G  G  G +G PG  G  G  G  G   DG QG PG  G  G PGEKG PG  G
Sbjct: 557  GDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPG 616

Query: 1134 SPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT------GDDGPKGNPGPVGFPG 1187
             PG  G PG+ GPRG  G+KG+ G PG+ G PG KG T      G  GP G PG  GFPG
Sbjct: 617  LPG-NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPG 675

Query: 1188 DPGPPGEGGPRGQDGAKGDRGEDGEPG------QPGSPGPTGENGPPGPLGKRGPAGSP- 1240
              G  G  G  GQ G+ G +GE G PG       PG PGP GE G PG  G  G  G P 
Sbjct: 676  PKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPG 735

Query: 1241 --GSEGRQGGKGAKGD--------PGAIGAPGKTGPVGPAGPAGKP------------GP 1278
              GS G  G KGA GD        PG  G  G TG  G  G +G P            GP
Sbjct: 736  MIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGP 795

Query: 1279 DGLRGLPGSVGQQGRPGATGQAGP---------PGPVGPPGLPGLRGDAGAKGEKGHPGL 1329
             G RG PG+ GQ G+PG  G +GP         PG  G PG+ G  G  G +G+KG PG 
Sbjct: 796  KGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGS 855

Query: 1330 IGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIG----------PG--GPPGL 1377
            I   G PG +G  G+ GL G +GSPG  G  G+P  SGP G          PG  G PG+
Sbjct: 856  IVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGI 915

Query: 1378 PGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQ 1437
            PG  G KG  G+TG  GP G  G  G  G  G PG V  P P       RR +    L  
Sbjct: 916  PGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSP-------RRPMSNLWLKG 968

Query: 1438 EDEAIPTGGAPGSPG 1452
            +  +  + G+ G PG
Sbjct: 969  DKGSQGSAGSNGFPG 983



 Score =  437 bits (1125), Expect = e-122
 Identities = 287/727 (39%), Positives = 349/727 (48%), Gaps = 97/727 (13%)

Query: 263  PQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGML-VEGPPGPEGPA 321
            P+ +  +PG   ++ +     P    + GP G+KG+ G P    PG   + G PG +G  
Sbjct: 795  PKGERGSPGTPGQVGQ-----PGTPGSSGPYGIKGKSGLPGA--PGFPGISGHPGKKGTR 847

Query: 322  GLIGPP------------GIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFR 369
            G  GPP            G+ GNPG VG  G  G PG AGLP   G  G  G+   + F 
Sbjct: 848  GKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFP 907

Query: 370  FGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQP----------- 418
             G  G    P     +    +  +       G PG  G  G PGP+G P           
Sbjct: 908  -GIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWL 966

Query: 419  ----GSPGLKGESGDLGPQGPRGPQGLTGPPGKAGR----------RGRAGADGARGMPG 464
                GS G  G +G  GP+G +G  G  GPPG  G            G+ G  G  G+ G
Sbjct: 967  KGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRG 1026

Query: 465  DPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI-------GPRGLP 517
             PG+KG  G  G PG+PGE G +G  G+ GLPG  G  G +GD+G+        GP+G P
Sbjct: 1027 LPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQP 1086

Query: 518  GESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGP- 576
            GESG +G  G  G  G  G PG +G DG  G  G +G  G PG PG  G  G  GLPG  
Sbjct: 1087 GESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSS 1146

Query: 577  --QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS--GPQGPLGYPG 632
              QGAIGP G  G  G  G PG PG  G  G PG +   GT G  GPS  G  GP G PG
Sbjct: 1147 GHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTK---GTHGTPGPSITGVPGPAGLPG 1203

Query: 633  PRGVKGVDGI----RGLKGHKGEKGEDGFPGFKGDIGVKGDRG------EVGVPGSRGED 682
            P+G KG  GI     G  G +G+KG+ GFPG +G  G+ G  G        G PG  G  
Sbjct: 1204 PKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRP 1263

Query: 683  GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGAR 742
            G +G +GR GP G PGPPG    +G  G PG PG PG +GPKG  G PGF G  GE G +
Sbjct: 1264 GLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLK 1323

Query: 743  GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 802
            G+ G+ G  G  G  GP G  G  G  GK+G +G+S   G  G PG+   P  +     P
Sbjct: 1324 GMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSS---GLQGDPGQ--TPTAEAVQVPP 1378

Query: 803  GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 862
            GP G PG  G  GL G PG +G VG QG  G PG PG  GP G             PGPP
Sbjct: 1379 GPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGL------------PGPP 1426

Query: 863  GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPS 922
            G  G+ GLP      G +G PG  GAPG+ GP G+ G PG+       G   +K ++   
Sbjct: 1427 GALGDPGLP------GLQGPPGFEGAPGQQGPFGMPGMPGQ---SMRVGYTLVKHSQSEQ 1477

Query: 923  GPPGPAG 929
             PP P G
Sbjct: 1478 VPPCPIG 1484



 Score =  105 bits (262), Expect = 4e-22
 Identities = 73/191 (38%), Positives = 86/191 (45%), Gaps = 11/191 (5%)

Query: 1264 TGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1323
            T  +  AG      P G +   GS       GA G+ GP G  GP G  G  G  G  G 
Sbjct: 15   TEELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGL 74

Query: 1324 KGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGP 1383
            KG  G  GL+GP G +G+KG  G+      PG  G  GIPG  G  GP GPPGL    G 
Sbjct: 75   KGERGFPGLLGPYGPKGDKGPMGV------PGFLGINGIPGHPGQPGPRGPPGLD---GC 125

Query: 1384 KGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP 1443
             G +GA G  GP G  G+ GPPG PG  G   +  P+  P   +       L   D    
Sbjct: 126  NGTQGAVGFPGPDGYPGLLGPPGLPGQKGS--KGDPVLAPGSFKGMKGDPGLPGLDGITG 183

Query: 1444 TGGAPGSPGGL 1454
              GAPG PG +
Sbjct: 184  PQGAPGFPGAV 194


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.144    0.459 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 124,597,203
Number of Sequences: 37866
Number of extensions: 11263556
Number of successful extensions: 380413
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 622
Number of HSP's successfully gapped in prelim test: 2051
Number of HSP's that attempted gapping in prelim test: 38822
Number of HSP's gapped (non-prelim): 58708
length of query: 1650
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1534
effective length of database: 13,855,062
effective search space: 21253665108
effective search space used: 21253665108
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.