Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 111118968

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein
[Homo sapiens]
         (1629 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...  3488   0.0  
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...  3476   0.0  
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...  3311   0.0  
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...  2360   0.0  
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]     2290   0.0  
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...  2243   0.0  
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...  2243   0.0  
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]  1771   0.0  
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...  1160   0.0  
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...  1158   0.0  
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]    1138   0.0  
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]     1123   0.0  
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]    1104   0.0  
gi|48762934 alpha 2 type I collagen [Homo sapiens]                   1023   0.0  
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   993   0.0  
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   991   0.0  
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   986   0.0  
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]              943   0.0  
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         931   0.0  
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]    910   0.0  
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]               910   0.0  
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...   895   0.0  
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...   894   0.0  
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...   894   0.0  
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...   894   0.0  
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]        886   0.0  
gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]              871   0.0  
gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens]    832   0.0  
gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ...   805   0.0  
gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo s...   805   0.0  

>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score = 3488 bits (9044), Expect = 0.0
 Identities = 1629/1629 (100%), Positives = 1629/1629 (100%)

Query: 1    MERCSRCHRLLLLLPLVLGLSAAPGWAGAPPVDVLRALRFPSLPDGVRRAKGICPADVAY 60
            MERCSRCHRLLLLLPLVLGLSAAPGWAGAPPVDVLRALRFPSLPDGVRRAKGICPADVAY
Sbjct: 1    MERCSRCHRLLLLLPLVLGLSAAPGWAGAPPVDVLRALRFPSLPDGVRRAKGICPADVAY 60

Query: 61   RVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPV 120
            RVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPV
Sbjct: 61   RVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPV 120

Query: 121  RFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSAR 180
            RFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSAR
Sbjct: 121  RFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSAR 180

Query: 181  PVLDTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQ 240
            PVLDTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQ
Sbjct: 181  PVLDTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQ 240

Query: 241  PHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPA 300
            PHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPA
Sbjct: 241  PHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPA 300

Query: 301  GLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVV 360
            GLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVV
Sbjct: 301  GLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVV 360

Query: 361  AAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGL 420
            AAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGL
Sbjct: 361  AAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGL 420

Query: 421  TGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGE 480
            TGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGE
Sbjct: 421  TGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGE 480

Query: 481  DGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP 540
            DGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP
Sbjct: 481  DGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP 540

Query: 541  PGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGP 600
            PGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGP
Sbjct: 541  PGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGP 600

Query: 601  SGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGE 660
            SGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGE
Sbjct: 601  SGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGE 660

Query: 661  DGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGA 720
            DGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGA
Sbjct: 661  DGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGA 720

Query: 721  RGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGF 780
            RGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGF
Sbjct: 721  RGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGF 780

Query: 781  PGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGP 840
            PGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGP
Sbjct: 781  PGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGP 840

Query: 841  PGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGP 900
            PGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGP
Sbjct: 841  PGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGP 900

Query: 901  SGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGP 960
            SGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGP
Sbjct: 901  SGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGP 960

Query: 961  VGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGE 1020
            VGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGE
Sbjct: 961  VGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGE 1020

Query: 1021 PGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGP 1080
            PGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGP
Sbjct: 1021 PGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGP 1080

Query: 1081 AGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGE 1140
            AGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGE
Sbjct: 1081 AGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGE 1140

Query: 1141 PGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGP 1200
            PGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGP
Sbjct: 1141 PGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGP 1200

Query: 1201 TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL 1260
            TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL
Sbjct: 1201 TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL 1260

Query: 1261 RGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGE 1320
            RGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGE
Sbjct: 1261 RGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGE 1320

Query: 1321 KGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGV 1380
            KGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGV
Sbjct: 1321 KGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGV 1380

Query: 1381 QGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSL 1440
            QGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSL
Sbjct: 1381 QGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSL 1440

Query: 1441 DSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTA 1500
            DSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTA
Sbjct: 1441 DSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTA 1500

Query: 1501 GGETCVTPRDDVTQFSYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPCSGAARDGPLRLR 1560
            GGETCVTPRDDVTQFSYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPCSGAARDGPLRLR
Sbjct: 1501 GGETCVTPRDDVTQFSYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPCSGAARDGPLRLR 1560

Query: 1561 GANEDELSPETSPYVKEFRDGCQTQQGRTVLEVRTPVLEQLPVLDASFSDLGAPPRRGGV 1620
            GANEDELSPETSPYVKEFRDGCQTQQGRTVLEVRTPVLEQLPVLDASFSDLGAPPRRGGV
Sbjct: 1561 GANEDELSPETSPYVKEFRDGCQTQQGRTVLEVRTPVLEQLPVLDASFSDLGAPPRRGGV 1620

Query: 1621 LLGPVCFMG 1629
            LLGPVCFMG
Sbjct: 1621 LLGPVCFMG 1629


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score = 3476 bits (9012), Expect = 0.0
 Identities = 1629/1650 (98%), Positives = 1629/1650 (98%), Gaps = 21/1650 (1%)

Query: 1    MERCSRCHRLLLLLPLVLGLSAAPGWAGAPPVDVLRALRFPSLPDGVRRAKGICPADVAY 60
            MERCSRCHRLLLLLPLVLGLSAAPGWAGAPPVDVLRALRFPSLPDGVRRAKGICPADVAY
Sbjct: 1    MERCSRCHRLLLLLPLVLGLSAAPGWAGAPPVDVLRALRFPSLPDGVRRAKGICPADVAY 60

Query: 61   RVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPV 120
            RVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPV
Sbjct: 61   RVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPV 120

Query: 121  RFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSAR 180
            RFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSAR
Sbjct: 121  RFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSAR 180

Query: 181  PVLDTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQ 240
            PVLDTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQ
Sbjct: 181  PVLDTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQ 240

Query: 241  PHRAQRSPQQQPSRLHRPQNQEPQSQ---------------------AAHGPRGLKGEKG 279
            PHRAQRSPQQQPSRLHRPQNQEPQSQ                     AAHGPRGLKGEKG
Sbjct: 241  PHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKG 300

Query: 280  EPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPP 339
            EPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPP
Sbjct: 301  EPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPP 360

Query: 340  GTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGS 399
            GTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGS
Sbjct: 361  GTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGS 420

Query: 400  PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGL 459
            PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGL
Sbjct: 421  PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGL 480

Query: 460  PGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV 519
            PGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV
Sbjct: 481  PGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV 540

Query: 520  RGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGS 579
            RGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGS
Sbjct: 541  RGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGS 600

Query: 580  DGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF 639
            DGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF
Sbjct: 601  DGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF 660

Query: 640  KGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR 699
            KGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR
Sbjct: 661  KGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR 720

Query: 700  QGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGG 759
            QGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGG
Sbjct: 721  QGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGG 780

Query: 760  DGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV 819
            DGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV
Sbjct: 781  DGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV 840

Query: 820  VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGF 879
            VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGF
Sbjct: 841  VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGF 900

Query: 880  PGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGE 939
            PGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGE
Sbjct: 901  PGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGE 960

Query: 940  KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 999
            KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP
Sbjct: 961  KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 1020

Query: 1000 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1059
            PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE
Sbjct: 1021 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1080

Query: 1060 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1119
            KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE
Sbjct: 1081 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1140

Query: 1120 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQ 1179
            PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQ
Sbjct: 1141 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQ 1200

Query: 1180 DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGA 1239
            DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGA
Sbjct: 1201 DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGA 1260

Query: 1240 PGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGA 1299
            PGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGA
Sbjct: 1261 PGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGA 1320

Query: 1300 KGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGP 1359
            KGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGP
Sbjct: 1321 KGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGP 1380

Query: 1360 AGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDE 1419
            AGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDE
Sbjct: 1381 AGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDE 1440

Query: 1420 AIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEY 1479
            AIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEY
Sbjct: 1441 AIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEY 1500

Query: 1480 WVDPNQGCARDAFRVFCNFTAGGETCVTPRDDVTQFSYVDSEGSPVGVVQLTFLRLLSVS 1539
            WVDPNQGCARDAFRVFCNFTAGGETCVTPRDDVTQFSYVDSEGSPVGVVQLTFLRLLSVS
Sbjct: 1501 WVDPNQGCARDAFRVFCNFTAGGETCVTPRDDVTQFSYVDSEGSPVGVVQLTFLRLLSVS 1560

Query: 1540 AHQDVSYPCSGAARDGPLRLRGANEDELSPETSPYVKEFRDGCQTQQGRTVLEVRTPVLE 1599
            AHQDVSYPCSGAARDGPLRLRGANEDELSPETSPYVKEFRDGCQTQQGRTVLEVRTPVLE
Sbjct: 1561 AHQDVSYPCSGAARDGPLRLRGANEDELSPETSPYVKEFRDGCQTQQGRTVLEVRTPVLE 1620

Query: 1600 QLPVLDASFSDLGAPPRRGGVLLGPVCFMG 1629
            QLPVLDASFSDLGAPPRRGGVLLGPVCFMG
Sbjct: 1621 QLPVLDASFSDLGAPPRRGGVLLGPVCFMG 1650


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 3311 bits (8586), Expect = 0.0
 Identities = 1585/1736 (91%), Positives = 1593/1736 (91%), Gaps = 107/1736 (6%)

Query: 1    MERCSRCHRLLLLLPLVLGLSAAPGWAGAPPVDVLRALRFPSLPDGVRRAKGICPADVAY 60
            MERCSRCHRLLLLLPLVLGLSAAPGWAGAPPVDVLRALRFPSLPDGVRRAKGICPADVAY
Sbjct: 1    MERCSRCHRLLLLLPLVLGLSAAPGWAGAPPVDVLRALRFPSLPDGVRRAKGICPADVAY 60

Query: 61   RVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPV 120
            RVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPV
Sbjct: 61   RVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPV 120

Query: 121  RFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSAR 180
            RFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSAR
Sbjct: 121  RFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSAR 180

Query: 181  PVLDTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQ 240
            PVLDTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQ
Sbjct: 181  PVLDTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQ 240

Query: 241  PHRAQRSPQQQPSRLHRPQNQEPQSQAAHG-------------PRGLKGEKGEPA----- 282
            PHRAQRSPQQQPSRLHRPQNQEPQSQ                   G   +  +P      
Sbjct: 241  PHRAQRSPQQQPSRLHRPQNQEPQSQPTESLYYDYEPPYYDVMTTGTTPDYQDPTPGEEE 300

Query: 283  -VLEPGML---------VEGPP----------------GPEGPAGL-------------I 303
             +LE  +L         ++ PP                 PEGP                +
Sbjct: 301  EILESSLLPPLEEEQTDLQVPPTADRFQAEEYGEGGTDPPEGPYDYTYGYGDDYREETEL 360

Query: 304  GP----------PGIQGNPGPVGDPGE----------RGPPGRAGLPGSDGAPG------ 337
            GP              G  G  G+ GE           GPPG  G  G  G PG      
Sbjct: 361  GPALSAETAHSGAAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPG 420

Query: 338  ------------------------PPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQ 373
                                    PPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQ
Sbjct: 421  PVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQ 480

Query: 374  ARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRA 433
            ARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRA
Sbjct: 481  ARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRA 540

Query: 434  GADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPR 493
            GADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPR
Sbjct: 541  GADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPR 600

Query: 494  GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP 553
            GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP
Sbjct: 601  GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP 660

Query: 554  GPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR 613
            GPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR
Sbjct: 661  GPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR 720

Query: 614  GVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPT 673
            GVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPT
Sbjct: 721  GVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPT 780

Query: 674  GDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER 733
            GDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER
Sbjct: 781  GDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER 840

Query: 734  GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKD 793
            GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKD
Sbjct: 841  GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKD 900

Query: 794  GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTA 853
            GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTA
Sbjct: 901  GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTA 960

Query: 854  GKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGER 913
            GKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGER
Sbjct: 961  GKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGER 1020

Query: 914  GAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA 973
            GAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA
Sbjct: 1021 GAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA 1080

Query: 974  GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK 1033
            GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK
Sbjct: 1081 GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK 1140

Query: 1034 GDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPP 1093
            GDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPP
Sbjct: 1141 GDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPP 1200

Query: 1094 GGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD 1153
            GGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD
Sbjct: 1201 GGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD 1260

Query: 1154 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1213
            GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR
Sbjct: 1261 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1320

Query: 1214 GPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRP 1273
            GPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRP
Sbjct: 1321 GPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRP 1380

Query: 1274 GATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSP 1333
            GATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSP
Sbjct: 1381 GATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSP 1440

Query: 1334 GQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEV 1393
            GQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEV
Sbjct: 1441 GQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEV 1500

Query: 1394 IQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRP 1453
            IQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRP
Sbjct: 1501 IQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRP 1560

Query: 1454 TGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGETCVTPRDDVT 1513
            TGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGETCVTPRDDVT
Sbjct: 1561 TGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGETCVTPRDDVT 1620

Query: 1514 QFSYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPCSGAARDGPLRLRGANEDELSPETSP 1573
            QFSYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPCSGAARDGPLRLRGANEDELSPETSP
Sbjct: 1621 QFSYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPCSGAARDGPLRLRGANEDELSPETSP 1680

Query: 1574 YVKEFRDGCQTQQGRTVLEVRTPVLEQLPVLDASFSDLGAPPRRGGVLLGPVCFMG 1629
            YVKEFRDGCQTQQGRTVLEVRTPVLEQLPVLDASFSDLGAPPRRGGVLLGPVCFMG
Sbjct: 1681 YVKEFRDGCQTQQGRTVLEVRTPVLEQLPVLDASFSDLGAPPRRGGVLLGPVCFMG 1736


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 2360 bits (6116), Expect = 0.0
 Identities = 1124/1741 (64%), Positives = 1299/1741 (74%), Gaps = 147/1741 (8%)

Query: 28   GAPPVDVLRALRFPSLPDGVRRAKGICP-------ADVAYRVARPAQLSAPTRQLFPGG- 79
            GA PVDVL+AL F + P+G+ +  G C        +D AYRV++ AQLSAPT+QLFPGG 
Sbjct: 35   GAAPVDVLKALDFHNSPEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGT 94

Query: 80   FPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPVRFLYEDQTGRPQPPSQPVF 139
            FP+DFS+L  V+ + G+Q+ LL++Y+  G++Q+G+E+GR   FL+ED TG+P P   P+F
Sbjct: 95   FPEDFSILFTVKPKKGIQSFLLSIYNEHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLF 154

Query: 140  RGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSARPVLDTHGVIIFGARILDEE 199
            R +++ADGKWHRVA++V+ ++VT+IVDCKK+ T+PL RS R ++DT+G+ +FG RILDEE
Sbjct: 155  RTVNIADGKWHRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEE 214

Query: 200  VFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQP---------------HRA 244
            VFEGD+Q+  I    +AAY+ CE    +C+    +  Q Q+P               +  
Sbjct: 215  VFEGDIQQFLITGDPKAAYDYCEHYSPDCDSSAPKAAQAQEPQIDEANIVDDFQEYNYGT 274

Query: 245  QRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGE-------KGEPAVLE--------PGML 289
              S Q +  R     N+    +       L GE         E  + E          +L
Sbjct: 275  MESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLL 334

Query: 290  VEG-------------------PP----GPEGPA------------GLIGPPGIQGNP-- 312
            V+G                   PP    GP  PA            G  G  G +G P  
Sbjct: 335  VDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAV 394

Query: 313  -----------GPVGDPGERGP------------------PGRAGLPGSDGAPGPPGTSL 343
                       GP G  G  GP                  PGR GLPG+DG PGPPGT L
Sbjct: 395  VEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTML 454

Query: 344  MLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLK 403
            MLPFR+G G G KGP ++AQEAQAQAILQQAR+ALRGPPGPMG TGRPGP+G PGS G K
Sbjct: 455  MLPFRYG-GDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAK 513

Query: 404  GESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEK 463
            GESGD GPQGPRG QG  GP GK G+RGR GADG RGMPG+PG KGDRGFDGLPGLPG+K
Sbjct: 514  GESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDK 573

Query: 464  GHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMD 523
            GHRG+ G QG PGPPG+DG RG+DGEIGPRGLPGE+GPRGLLGP+G PG PG PG+ G+D
Sbjct: 574  GHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVD 633

Query: 524  GPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPP 583
            GP GPKG++GPQGEPGPPGQQG PG QGLPGPQG IGP GEKGPQGKPGL G+PG+DGPP
Sbjct: 634  GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 693

Query: 584  GHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDI 643
            GHPGKEG  G KG  GP GPQGP+GYPGPRGVKG DG+RGLKG KGEKGEDGFPGFKGD+
Sbjct: 694  GHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDM 753

Query: 644  GVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPK 703
            G+KGDRGEVG  G RGEDGPEGPKGR GPTGDPGP G  GEKGKLGVPGLPGYPGRQGPK
Sbjct: 754  GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 813

Query: 704  GSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPH 763
            GS GFPGFPGA+GEKGARG++GK GPRG+RGPTGPRG RG RG TGK G KGTSGGDGP 
Sbjct: 814  GSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPP 873

Query: 764  GPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ 823
            GPPGERG  GPQGP GFPGPKGPPGPPGKDGLPGHPGQRGE GFQGKTGPPGP GVVGPQ
Sbjct: 874  GPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQ 933

Query: 824  GAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGER 883
            G  GETGP+GERGHPGPPGPPGEQGLPG AGKEG KGDPGP G  GKDGPAGLRGFPGER
Sbjct: 934  GPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGER 993

Query: 884  GLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVP 943
            GLPG  G PGLKG EGP GPPGP GSPGERG+AG+ GPIG PGRPGPQGPPG AGEKG P
Sbjct: 994  GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1053

Query: 944  GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPP 1003
            GEKGP GP GRDGVQGPVGLPGPAGP G  GEDGDKGE+G+PGQKG+KG+KGE+GPPGPP
Sbjct: 1054 GEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP 1113

Query: 1004 GPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET 1063
            G  GPVG PG AG DGEPG RG QG FG KGDEG RGF GPPGPIGLQGLPGP GEKGE 
Sbjct: 1114 GLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGEN 1173

Query: 1064 GDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVK 1123
            GDVGPMGPPGPPGPRGP GPNGADGPQGPPG VG++G  GEKGEPGE+G+PG  GE GV 
Sbjct: 1174 GDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVG 1233

Query: 1124 GPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAK 1183
            GP+GERGEKGE+G PG  GPPG KGP GDDGPKGNPGPVGFPGDPGPPGE GP GQDG  
Sbjct: 1234 GPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVG 1293

Query: 1184 GDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKT 1243
            GD+GEDG+PGQPG PGP+GE GPPGP GKRGP G+ G+EGRQG KGAKG+ GA G PGKT
Sbjct: 1294 GDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKT 1353

Query: 1244 GPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEK 1303
            GPVGP GPAGKPGP+GLRG+PG VG+QG PGA GQ GPPGP+GPPGLPGL+GD G+KGEK
Sbjct: 1354 GPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEK 1413

Query: 1304 GHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPK 1363
            GHPGLIGLIGPPGEQGEKGDRGLPG QGSPG KG+ GIPG +GP+GP GPPGLPGP GPK
Sbjct: 1414 GHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPK 1473

Query: 1364 GAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPT 1423
            G KG+TGP G KG+ G+ GPPG PGPPGEVIQPLPI   KKTRR  +G +   +D  +  
Sbjct: 1474 GNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADADDNILDY 1533

Query: 1424 GGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDP 1483
                    G+EEIFGSL+SL+++IE M+ P GTQ +PARTC+DL+L HP+ PDGEYW+DP
Sbjct: 1534 S------DGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDGEYWIDP 1587

Query: 1484 NQGCARDAFRVFCNFTAGGETCVTPRDDVTQ------------------------FSYVD 1519
            NQGC+ D+F+V+CNFT+GGETC+ P D  ++                         SY+D
Sbjct: 1588 NQGCSGDSFKVYCNFTSGGETCIYP-DKKSEGVRISSWPKEKPGSWFSEFKRGKLLSYLD 1646

Query: 1520 SEGSPVGVVQLTFLRLLSVSAHQDVSYPC---------SGAARDGPLRLRGANEDELSPE 1570
             EG+ + +VQ+TFL+LL+ SA Q+ +Y C         S  + D  LR  G+N++E+S +
Sbjct: 1647 VEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDEEMSYD 1706

Query: 1571 TSPYVKEFRDGCQTQQG--RTVLEVRTPVLEQLPVLDASFSDLGAPPRRGGVLLGPVCFM 1628
             +P++K   DGC +++G  +TV+E+ TP ++Q+P++D   +D G   ++ G  +GPVCF+
Sbjct: 1707 NNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVGPVCFL 1766

Query: 1629 G 1629
            G
Sbjct: 1767 G 1767


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 2290 bits (5935), Expect = 0.0
 Identities = 1061/1420 (74%), Positives = 1163/1420 (81%), Gaps = 42/1420 (2%)

Query: 248  PQQQPSRLH--RPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGP 305
            P   PS +    P NQ+   +   GPRG KG+KGEPA++EPGML+EGPPGPEGPAGL GP
Sbjct: 423  PTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGP 482

Query: 306  PGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--GDKGPVVAAQ 363
            PG  G  G VGDPGERGPPGR GLPG+DG PGPPGT LMLPFRFG GG  G KGP+V+AQ
Sbjct: 483  PGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQ 542

Query: 364  EAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGP 423
            E+QAQAILQQARLALRGP GPMG TGRPGP+G PGS GLKGE GD+GPQGPRG QG  GP
Sbjct: 543  ESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGP 602

Query: 424  PGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGE 483
             GK GRRGRAG+DGARGMPG  G KGDRGFDGL GLPGEKGHRGD G  G PGPPG+DGE
Sbjct: 603  AGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGE 662

Query: 484  RGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQ 543
            RGDDGE+GPRGLPGE GPRGLLGPKGPPG PGPPGV GMDG  GPKG++GPQGEPGPPGQ
Sbjct: 663  RGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQ 722

Query: 544  QGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGP 603
            QG PG QGLPGPQGAIGP GEKGP GKPGLPGMPG+DGPPGHPGKEGPPG KG QGP GP
Sbjct: 723  QGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGP 782

Query: 604  QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGP 663
            QGP+GYPGPRGVKG DGIRGLKG KGEKGEDGFPGFKGD+G+KGDRGE+G PG RGEDGP
Sbjct: 783  QGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGP 842

Query: 664  EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 723
            EGPKGR GP GDPGP G  GEKGKLGVPGLPGYPGRQGPKGS+GFPGFPGA+GEKG RG 
Sbjct: 843  EGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGT 902

Query: 724  SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 783
             GK GPRG+RGPTGPRG+RGPRG TGK G KG SGGDGP GPPGERG  GPQGP GFPGP
Sbjct: 903  PGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGP 962

Query: 784  KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 843
            KGPPGPPGKDGLPGHPGQRGE GFQGKTGPPGPPGVVGPQG  GETGPMGERGHPGPPGP
Sbjct: 963  KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGP 1022

Query: 844  PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 903
            PGEQGLPG AGKEGTKGDPGP G PGKDGP GLRGFPG+RGLPG  G  GLKGNEGP GP
Sbjct: 1023 PGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGP 1082

Query: 904  PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGL 963
            PGPAGSPGERG AG+ GPIG PGRPGPQGPPG AGEKG PGEKGP GP GRDG+QGPVGL
Sbjct: 1083 PGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGL 1142

Query: 964  PGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGA 1023
            PGPAGP G  GEDGDKGE+G+PGQKG+KG+KGE GPPGP GP GP+GQPG +GADGEPG 
Sbjct: 1143 PGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGP 1202

Query: 1024 RGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGP 1083
            RG QG FG KGDEG RGF GPPGP+GLQGLPGP GEKGETGDVG MGPPGPPGPRGP+G 
Sbjct: 1203 RGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGA 1262

Query: 1084 NGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGP 1143
             GADGPQGPPGG+GN G  GEKGEPGE+G PG+ GE G  GP+GERGEKGESG  G  GP
Sbjct: 1263 PGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGP 1322

Query: 1144 PGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGE 1203
            PGPKGP GDDGPKG+PGPVGFPGDPGPPGE GP GQDG  GD+G+DGEPGQ GSPGPTGE
Sbjct: 1323 PGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGE 1382

Query: 1204 NGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGL 1263
             GP GP GKRGP G  G EGRQG KGAKG+ G  G PGKTGP+GP G  GKPGPDGLRG+
Sbjct: 1383 PGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGI 1442

Query: 1264 PGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGD 1323
            PG VG+QG PG+ G  GPPGP+GPPGLPGL+GD+G KGEKGHPGLIGLIGPPGEQGEKGD
Sbjct: 1443 PGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGD 1502

Query: 1324 RGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGP 1383
            RGLPGPQGS G KGE GI G SGPIGP GPPGLPGP GPKGAKG++GP GPKGE G  GP
Sbjct: 1503 RGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGP 1562

Query: 1384 PGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSL 1443
            PG PGPPGEVIQPLPIQ   +TRR++D S+L+ +              G+EEIFGSL+SL
Sbjct: 1563 PGPPGPPGEVIQPLPIQA-SRTRRNIDASQLLDDGNG---ENYVDYADGMEEIFGSLNSL 1618

Query: 1444 REEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGE 1503
            + EIEQM+RP GTQ +PARTC+DL+LCHP+ PDGEYWVDPNQGC+RD+F+V+CNFTAGG 
Sbjct: 1619 KLEIEQMKRPLGTQQNPARTCKDLQLCHPDFPDGEYWVDPNQGCSRDSFKVYCNFTAGGS 1678

Query: 1504 TCVTPRDD-----VTQF------------------SYVDSEGSPVGVVQLTFLRLLSVSA 1540
            TCV P        +T +                  SYVD+EG+PVGVVQ+TFLRLLS SA
Sbjct: 1679 TCVFPDKKSEGARITSWPKENPGSWFSEFKRGKLLSYVDAEGNPVGVVQMTFLRLLSASA 1738

Query: 1541 HQDVSYPC---------SGAARDGPLRLRGANEDELSPETSPYVKEFRDGCQTQQG--RT 1589
            HQ+V+Y C         +  + D  LR  G+N++E+S + +PY++   DGC T++G  +T
Sbjct: 1739 HQNVTYHCYQSVAWQDAATGSYDKALRFLGSNDEEMSYDNNPYIRALVDGCATKKGYQKT 1798

Query: 1590 VLEVRTPVLEQLPVLDASFSDLGAPPRRGGVLLGPVCFMG 1629
            VLE+ TP +EQ+P++D  F+D G   ++ G  +GP CFMG
Sbjct: 1799 VLEIDTPKVEQVPIVDIMFNDFGEASQKFGFEVGPACFMG 1838



 Score =  459 bits (1181), Expect = e-128
 Identities = 278/695 (40%), Positives = 319/695 (45%), Gaps = 136/695 (19%)

Query: 833  GERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAG------LR--------- 877
            GE     P  P     +P +        +P PP   G D   G      +R         
Sbjct: 360  GEENPDQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYDP 419

Query: 878  -------------GFPGER-----GLPGTAGGPGLKGN----------EGPSGPPGPAGS 909
                         G P  +     G+ G  G  G KG           EGP GP GPAG 
Sbjct: 420  YYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGL 479

Query: 910  PGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPI-------GPTGRDGVQGP-- 960
            PG  G  G  G +G PG  GP G PG  G  G+PG  G +       G  G  G +GP  
Sbjct: 480  PGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMV 539

Query: 961  ---------------VGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGP 1005
                           + L GPAGP G+ G  G  G  G  G KG  G+ G  GP G  GP
Sbjct: 540  SAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGP 599

Query: 1006 IGPVGQPGAAGADGEPGARGPQGHFGAKGDE---------GTRGFNGPPGPIGLQGLPGP 1056
             GP G+PG  G  G  GARG  G  G KGD          G +G  G PGP G  G PG 
Sbjct: 600  PGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGD 659

Query: 1057 SGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGV---------GNLGPPGEKGE 1107
             GE+G+ G+VGP G PG PGPRG  GP G  GP GPPG           GN+GP GE G 
Sbjct: 660  DGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGP 719

Query: 1108 PGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP-------- 1159
            PG+ G+PG QG PG +G  G  GEKG  G+PG PG PG  GP G  G +G P        
Sbjct: 720  PGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGP 779

Query: 1160 ----GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEP------------GQPGSPGPTGE 1203
                GP+G+PG  G  G  G RG  G KG++GEDG P            G+ G PGP GE
Sbjct: 780  PGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGE 839

Query: 1204 NGPPGPLGKRGPAGSPGS------------------EGRQGGK---------GAKGDPGA 1236
            +GP GP G+ GP G PG                    GRQG K         GA G+ G 
Sbjct: 840  DGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGG 899

Query: 1237 IGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGD 1296
             G PGK GP G  GP G  G  G RG+ G  G +G  G  G AGPPG  GP G  G  G 
Sbjct: 900  RGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGF 959

Query: 1297 AGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGL 1356
             G KG  G PG  GL G PG++GE G +G  GP G PG  G  G  G +GP+G  G PG 
Sbjct: 960  PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGP 1019

Query: 1357 PGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1391
            PGP G +G  G  G  G KG+ G  G PG  GPPG
Sbjct: 1020 PGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPG 1054


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 2243 bits (5813), Expect = 0.0
 Identities = 1025/1395 (73%), Positives = 1148/1395 (82%), Gaps = 41/1395 (2%)

Query: 269  HGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAG 328
            HG  G KG+KGEPAV+EPGMLVEGPPGP GPAG++GPPG+QG  GP GDPG+RGPPGR G
Sbjct: 431  HGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPG 490

Query: 329  LPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYT 388
            LPG+DG PGPPGT LMLPFR+G G G KGP ++AQEAQAQAILQQAR+ALRGPPGPMG T
Sbjct: 491  LPGADGLPGPPGTMLMLPFRYG-GDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLT 549

Query: 389  GRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVK 448
            GRPGP+G PGS G KGESGD GPQGPRG QG  GP GK G+RGR GADG RGMPG+PG K
Sbjct: 550  GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAK 609

Query: 449  GDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPK 508
            GDRGFDGLPGLPG+KGHRG+ G QG PGPPG+DG RG+DGEIGPRGLPGE+GPRGLLGP+
Sbjct: 610  GDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPR 669

Query: 509  GPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQ 568
            G PG PG PG+ G+DGP GPKG++GPQGEPGPPGQQG PG QGLPGPQG IGP GEKGPQ
Sbjct: 670  GTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQ 729

Query: 569  GKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHK 628
            GKPGL G+PG+DGPPGHPGKEG  G KG  GP GPQGP+GYPGPRGVKG DG+RGLKG K
Sbjct: 730  GKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSK 789

Query: 629  GEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKL 688
            GEKGEDGFPGFKGD+G+KGDRGEVG  G RGEDGPEGPKGR GPTGDPGP G  GEKGKL
Sbjct: 790  GEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKL 849

Query: 689  GVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGAT 748
            GVPGLPGYPGRQGPKGS GFPGFPGA+GEKGARG++GK GPRG+RGPTGPRG RG RG T
Sbjct: 850  GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPT 909

Query: 749  GKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQ 808
            GK G KGTSGGDGP GPPGERG  GPQGP GFPGPKGPPGPPGKDGLPGHPGQRGE GFQ
Sbjct: 910  GKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 969

Query: 809  GKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP 868
            GKTGPPGP GVVGPQG  GETGP+GERGHPGPPGPPGEQGLPG AGKEG KGDPGP G  
Sbjct: 970  GKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGIS 1029

Query: 869  GKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP 928
            GKDGPAGLRGFPGERGLPG  G PGLKG EGP GPPGP GSPGERG+AG+ GPIG PGRP
Sbjct: 1030 GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRP 1089

Query: 929  GPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQK 988
            GPQGPPG AGEKG PGEKGP GP GRDGVQGPVGLPGPAGP G  GEDGDKGE+G+PGQK
Sbjct: 1090 GPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQK 1149

Query: 989  GTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPI 1048
            G+KG+KGE+GPPGPPG  GPVG PG AG DGEPG RG QG FG KGDEG RGF GPPGPI
Sbjct: 1150 GSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPI 1209

Query: 1049 GLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP 1108
            GLQGLPGP GEKGE GDVGPMGPPGPPGPRGP GPNGADGPQGPPG VG++G  GEKGEP
Sbjct: 1210 GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEP 1269

Query: 1109 GESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDP 1168
            GE+G+PG  GE GV GP+GERGEKGE+G PG  GPPG KGP GDDGPKGNPGPVGFPGDP
Sbjct: 1270 GEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDP 1329

Query: 1169 GPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGK 1228
            GPPGE GP GQDG  GD+GEDG+PGQPG PGP+GE GPPGP GKRGP G+ G+EGRQG K
Sbjct: 1330 GPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEK 1389

Query: 1229 GAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPP 1288
            GAKG+ GA G PGKTGPVGP GPAGKPGP+GLRG+PG VG+QG PGA GQ GPPGP+GPP
Sbjct: 1390 GAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPP 1449

Query: 1289 GLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPI 1348
            GLPGL+GD G+KGEKGHPGLIGLIGPPGEQGEKGDRGLPG QGSPG KG+ GIPG +GP+
Sbjct: 1450 GLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPL 1509

Query: 1349 GPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRS 1408
            GP GPPGLPGP GPKG KG+TGP G KG+ G+ GPPG PGPPGEVIQPLPI   KKTRR 
Sbjct: 1510 GPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRH 1569

Query: 1409 VDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLK 1468
             +G +   +D  +          G+EEIFGSL+SL+++IE M+ P GTQ +PARTC+DL+
Sbjct: 1570 TEGMQADADDNILDYSD------GMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQ 1623

Query: 1469 LCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGETCVTPRDD----------------- 1511
            L HP+ PDGEYW+DPNQGC+ D+F+V+CNFT+GGETC+ P                    
Sbjct: 1624 LSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSWPKEKPGSW 1683

Query: 1512 VTQF------SYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPC---------SGAARDGP 1556
             ++F      SY+D EG+ + +VQ+TFL+LL+ SA Q+ +Y C         S  + D  
Sbjct: 1684 FSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKA 1743

Query: 1557 LRLRGANEDELSPETSPYVKEFRDGCQTQQG--RTVLEVRTPVLEQLPVLDASFSDLGAP 1614
            LR  G+N++E+S + +P++K   DGC +++G  +TV+E+ TP ++Q+P++D   +D G  
Sbjct: 1744 LRFLGSNDEEMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMINDFGDQ 1803

Query: 1615 PRRGGVLLGPVCFMG 1629
             ++ G  +GPVCF+G
Sbjct: 1804 NQKFGFEVGPVCFLG 1818



 Score =  630 bits (1624), Expect = e-180
 Identities = 375/832 (45%), Positives = 424/832 (50%), Gaps = 80/832 (9%)

Query: 266  QAAHGPRGLKGEKGEPAVLE-PGMLVE-------------GPPGPEGPAGLIGPPGIQGN 311
            + A G RGLKG KGE      PG   +             GP G +GP G  G  G  G+
Sbjct: 777  KGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGD 836

Query: 312  PGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAIL 371
            PGP G  GE+G  G  GLPG  G  GP G S   P  F    G+KG    A +   +   
Sbjct: 837  PGPSGQAGEKGKLGVPGLPGYPGRQGPKG-STGFP-GFPGANGEKGARGVAGKPGPR--- 891

Query: 372  QQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRG 431
                   RGP GP G  G  GP G+PG  G  G  G  GP G RGPQG  GP G  G +G
Sbjct: 892  -----GQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKG 946

Query: 432  RAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIG 491
              G  G  G+PG PG +G+ GF G  G P      G  G  G  GP GE G  G+ G  G
Sbjct: 947  PPGPPGKDGLPGHPGQRGETGFQGKTGPP------GPGGVVGPQGPTGETGPIGERGHPG 1000

Query: 492  PRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEP---GPPGQQGTPG 548
            P G PGE G  G  G +G  G PGP G+ G DGP G +G  G +G P   G PG +G  G
Sbjct: 1001 PPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEG 1060

Query: 549  TQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS---GPQG 605
             QG PGP G+ G  G  G  G  GLPG PG  GPPG  G++G PG KG QGP+   G QG
Sbjct: 1061 PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQG 1120

Query: 606  PLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEG 665
            P+G PGP G        G  G  G+KGE G PG KG    KGD+GE G PG  G  GP G
Sbjct: 1121 PVGLPGPAGP------AGSPGEDGDKGEIGEPGQKGS---KGDKGENGPPGPPGLQGPVG 1171

Query: 666  PKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSG 725
              G  G  G+PGP G  G  G+ G  G  G+PG  GP G  G PG PG  GE G  G  G
Sbjct: 1172 APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMG 1231

Query: 726  KSGPRGERGPTGPRGQRGPRGATGKSGA------KGTSGGDGPHGPPGERGLPGPQGPNG 779
              GP G RGP GP G  GP+G  G  G+      KG  G  G  GPPGE G+ GP+G  G
Sbjct: 1232 PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERG 1291

Query: 780  FPGPKGPP---GPPGKDGLPGHPGQRGE---VGFQGKTGPPGPPGVVGPQGAAGETGPMG 833
              G  GPP   GPPG  G PG  G +G    VGF G  GPPG PG  G  G  G+ G  G
Sbjct: 1292 EKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDG 1351

Query: 834  ERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPG 893
            + G PGPPGP GE             G PGPPG  G  G AG  G  GE+G  G AG  G
Sbjct: 1352 DPGQPGPPGPSGE------------AGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEG 1399

Query: 894  LKGNEGPSGPPGPAGSPGERGAAGSGGPIGP---PGRPGPQGPPGAAGEKGVPGEKGPIG 950
              G  GP GP GPAG PG  G  G  GP+G    PG  G  GPPG  G  G+PG KG  G
Sbjct: 1400 PPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPG 1459

Query: 951  PTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVG 1010
              G  G  G +GL GP G  G      +KG+ G PG +G+ G KG+ G PGP GP+GP G
Sbjct: 1460 SKGEKGHPGLIGLIGPPGEQG------EKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPG 1513

Query: 1011 QPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIG--LQGLPGPSGEK 1060
             PG  G  G  G +G  G  G KGD G  G  G PGP G  +Q LP  S +K
Sbjct: 1514 PPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKK 1565



 Score =  365 bits (936), Expect = e-100
 Identities = 223/525 (42%), Positives = 255/525 (48%), Gaps = 92/525 (17%)

Query: 960  PVGLPGPAGPPGVAGE-DGDKGEVGDPGQKGTKGNKGE----------HGPPGPPGP--- 1005
            P   P     PGV  E D  +  +   G  G KG KGE           GPPGP GP   
Sbjct: 405  PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 464

Query: 1006 IGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRG------------------------- 1040
            +GP G  G  G  G+PG RGP G  G  G +G  G                         
Sbjct: 465  MGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQ 524

Query: 1041 --------------FNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR---GPAGP 1083
                            GPPGP+GL G PGP G  G +G  G  G PGP GPR   GP GP
Sbjct: 525  EAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGP 584

Query: 1084 NGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP----- 1138
             G  G +G PG  G  G PGE G  G+ G  G+ G PG KG RGERG +G  G P     
Sbjct: 585  TGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGM 644

Query: 1139 -GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGS 1197
             GE G  GP+G  G+ GP+G  GP G PG PG PG  G  G  G KG+ G  GEPG PG 
Sbjct: 645  RGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQ 704

Query: 1198 ---------PGPTGENGPP---GPLGKRGPAGSPGSE---GRQGGKGAKGDPGAIGAPGK 1242
                     PGP G  GPP   GP GK G AG PG++   G  G +G  G+ GA+G PG 
Sbjct: 705  QGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGP 764

Query: 1243 TGPVGPAGPAGKPGPDGLRGLPGSVGQQGR---PGATGQAGPPGPVGPPGLPGLRGDAGA 1299
             GP+G  GP G  G DG+RGL GS G++G    PG  G  G  G  G  G  G RG+ G 
Sbjct: 765  QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGP 824

Query: 1300 KGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQ---KGEMGIP---------GASGP 1347
            +G KG  G  G  GP G+ GEKG  G+PG  G PG+   KG  G P         GA G 
Sbjct: 825  EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV 884

Query: 1348 IGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGE 1392
             G  GP G  GP GP+G++GA GP G  G KG  G  G PGPPGE
Sbjct: 885  AGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGE 929



 Score =  238 bits (608), Expect = 3e-62
 Identities = 112/222 (50%), Positives = 162/222 (72%), Gaps = 8/222 (3%)

Query: 28  GAPPVDVLRALRFPSLPDGVRRAKGICP-------ADVAYRVARPAQLSAPTRQLFPGG- 79
           GA PVDVL+AL F + P+G+ +  G C        +D AYRV++ AQLSAPT+QLFPGG 
Sbjct: 35  GAAPVDVLKALDFHNSPEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGT 94

Query: 80  FPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPVRFLYEDQTGRPQPPSQPVF 139
           FP+DFS+L  V+ + G+Q+ LL++Y+  G++Q+G+E+GR   FL+ED TG+P P   P+F
Sbjct: 95  FPEDFSILFTVKPKKGIQSFLLSIYNEHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLF 154

Query: 140 RGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSARPVLDTHGVIIFGARILDEE 199
           R +++ADGKWHRVA++V+ ++VT+IVDCKK+ T+PL RS R ++DT+G+ +FG RILDEE
Sbjct: 155 RTVNIADGKWHRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEE 214

Query: 200 VFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQP 241
           VFEGD+Q+  I    +AAY+ CE    +C+    +  Q Q+P
Sbjct: 215 VFEGDIQQFLITGDPKAAYDYCEHYSPDCDSSAPKAAQAQEP 256



 Score =  233 bits (594), Expect = 1e-60
 Identities = 136/307 (44%), Positives = 153/307 (49%), Gaps = 47/307 (15%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPP---GIQGNPGPVGDPG 319
            P      GP+G +GEKGE           GPPG  GP G  GPP   G +GNPGPVG PG
Sbjct: 1278 PGEAGVGGPKGERGEKGE----------AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPG 1327

Query: 320  ERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALR 379
            + GPPG  G  G DG  G  G             G  GP   + EA              
Sbjct: 1328 DPGPPGEPGPAGQDGVGGDKGED--------GDPGQPGPPGPSGEA-------------- 1365

Query: 380  GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPR------GPQGLTGPPGKAGRRGRA 433
            GPPGP G  G PG  G  G  G KG  G+ G +GP       GPQG  G PG  G RG  
Sbjct: 1366 GPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIP 1425

Query: 434  GADGARGMP------GDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDD 487
            G  G +G+P      G PG  G  G  GL G PG KG +G  G  GL GPPGE GE+GD 
Sbjct: 1426 GPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDR 1485

Query: 488  GEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTP 547
            G  G +G PG  G  G+ GP GP G PGPPG+ G  GP+G KGS GP G+ G  G  G P
Sbjct: 1486 GLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPP 1545

Query: 548  GTQGLPG 554
            G+ G PG
Sbjct: 1546 GSPGPPG 1552


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 2243 bits (5813), Expect = 0.0
 Identities = 1025/1395 (73%), Positives = 1148/1395 (82%), Gaps = 41/1395 (2%)

Query: 269  HGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAG 328
            HG  G KG+KGEPAV+EPGMLVEGPPGP GPAG++GPPG+QG  GP GDPG+RGPPGR G
Sbjct: 419  HGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPG 478

Query: 329  LPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYT 388
            LPG+DG PGPPGT LMLPFR+G G G KGP ++AQEAQAQAILQQAR+ALRGPPGPMG T
Sbjct: 479  LPGADGLPGPPGTMLMLPFRYG-GDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLT 537

Query: 389  GRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVK 448
            GRPGP+G PGS G KGESGD GPQGPRG QG  GP GK G+RGR GADG RGMPG+PG K
Sbjct: 538  GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAK 597

Query: 449  GDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPK 508
            GDRGFDGLPGLPG+KGHRG+ G QG PGPPG+DG RG+DGEIGPRGLPGE+GPRGLLGP+
Sbjct: 598  GDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPR 657

Query: 509  GPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQ 568
            G PG PG PG+ G+DGP GPKG++GPQGEPGPPGQQG PG QGLPGPQG IGP GEKGPQ
Sbjct: 658  GTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQ 717

Query: 569  GKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHK 628
            GKPGL G+PG+DGPPGHPGKEG  G KG  GP GPQGP+GYPGPRGVKG DG+RGLKG K
Sbjct: 718  GKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSK 777

Query: 629  GEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKL 688
            GEKGEDGFPGFKGD+G+KGDRGEVG  G RGEDGPEGPKGR GPTGDPGP G  GEKGKL
Sbjct: 778  GEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKL 837

Query: 689  GVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGAT 748
            GVPGLPGYPGRQGPKGS GFPGFPGA+GEKGARG++GK GPRG+RGPTGPRG RG RG T
Sbjct: 838  GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPT 897

Query: 749  GKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQ 808
            GK G KGTSGGDGP GPPGERG  GPQGP GFPGPKGPPGPPGKDGLPGHPGQRGE GFQ
Sbjct: 898  GKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 957

Query: 809  GKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP 868
            GKTGPPGP GVVGPQG  GETGP+GERGHPGPPGPPGEQGLPG AGKEG KGDPGP G  
Sbjct: 958  GKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGIS 1017

Query: 869  GKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP 928
            GKDGPAGLRGFPGERGLPG  G PGLKG EGP GPPGP GSPGERG+AG+ GPIG PGRP
Sbjct: 1018 GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRP 1077

Query: 929  GPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQK 988
            GPQGPPG AGEKG PGEKGP GP GRDGVQGPVGLPGPAGP G  GEDGDKGE+G+PGQK
Sbjct: 1078 GPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQK 1137

Query: 989  GTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPI 1048
            G+KG+KGE+GPPGPPG  GPVG PG AG DGEPG RG QG FG KGDEG RGF GPPGPI
Sbjct: 1138 GSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPI 1197

Query: 1049 GLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP 1108
            GLQGLPGP GEKGE GDVGPMGPPGPPGPRGP GPNGADGPQGPPG VG++G  GEKGEP
Sbjct: 1198 GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEP 1257

Query: 1109 GESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDP 1168
            GE+G+PG  GE GV GP+GERGEKGE+G PG  GPPG KGP GDDGPKGNPGPVGFPGDP
Sbjct: 1258 GEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDP 1317

Query: 1169 GPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGK 1228
            GPPGE GP GQDG  GD+GEDG+PGQPG PGP+GE GPPGP GKRGP G+ G+EGRQG K
Sbjct: 1318 GPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEK 1377

Query: 1229 GAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPP 1288
            GAKG+ GA G PGKTGPVGP GPAGKPGP+GLRG+PG VG+QG PGA GQ GPPGP+GPP
Sbjct: 1378 GAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPP 1437

Query: 1289 GLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPI 1348
            GLPGL+GD G+KGEKGHPGLIGLIGPPGEQGEKGDRGLPG QGSPG KG+ GIPG +GP+
Sbjct: 1438 GLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPL 1497

Query: 1349 GPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRS 1408
            GP GPPGLPGP GPKG KG+TGP G KG+ G+ GPPG PGPPGEVIQPLPI   KKTRR 
Sbjct: 1498 GPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRH 1557

Query: 1409 VDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLK 1468
             +G +   +D  +          G+EEIFGSL+SL+++IE M+ P GTQ +PARTC+DL+
Sbjct: 1558 TEGMQADADDNILDYSD------GMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQ 1611

Query: 1469 LCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGETCVTPRDD----------------- 1511
            L HP+ PDGEYW+DPNQGC+ D+F+V+CNFT+GGETC+ P                    
Sbjct: 1612 LSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSWPKEKPGSW 1671

Query: 1512 VTQF------SYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPC---------SGAARDGP 1556
             ++F      SY+D EG+ + +VQ+TFL+LL+ SA Q+ +Y C         S  + D  
Sbjct: 1672 FSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKA 1731

Query: 1557 LRLRGANEDELSPETSPYVKEFRDGCQTQQG--RTVLEVRTPVLEQLPVLDASFSDLGAP 1614
            LR  G+N++E+S + +P++K   DGC +++G  +TV+E+ TP ++Q+P++D   +D G  
Sbjct: 1732 LRFLGSNDEEMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMINDFGDQ 1791

Query: 1615 PRRGGVLLGPVCFMG 1629
             ++ G  +GPVCF+G
Sbjct: 1792 NQKFGFEVGPVCFLG 1806



 Score =  630 bits (1624), Expect = e-180
 Identities = 375/832 (45%), Positives = 424/832 (50%), Gaps = 80/832 (9%)

Query: 266  QAAHGPRGLKGEKGEPAVLE-PGMLVE-------------GPPGPEGPAGLIGPPGIQGN 311
            + A G RGLKG KGE      PG   +             GP G +GP G  G  G  G+
Sbjct: 765  KGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGD 824

Query: 312  PGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAIL 371
            PGP G  GE+G  G  GLPG  G  GP G S   P  F    G+KG    A +   +   
Sbjct: 825  PGPSGQAGEKGKLGVPGLPGYPGRQGPKG-STGFP-GFPGANGEKGARGVAGKPGPR--- 879

Query: 372  QQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRG 431
                   RGP GP G  G  GP G+PG  G  G  G  GP G RGPQG  GP G  G +G
Sbjct: 880  -----GQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKG 934

Query: 432  RAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIG 491
              G  G  G+PG PG +G+ GF G  G P      G  G  G  GP GE G  G+ G  G
Sbjct: 935  PPGPPGKDGLPGHPGQRGETGFQGKTGPP------GPGGVVGPQGPTGETGPIGERGHPG 988

Query: 492  PRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEP---GPPGQQGTPG 548
            P G PGE G  G  G +G  G PGP G+ G DGP G +G  G +G P   G PG +G  G
Sbjct: 989  PPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEG 1048

Query: 549  TQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS---GPQG 605
             QG PGP G+ G  G  G  G  GLPG PG  GPPG  G++G PG KG QGP+   G QG
Sbjct: 1049 PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQG 1108

Query: 606  PLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEG 665
            P+G PGP G        G  G  G+KGE G PG KG    KGD+GE G PG  G  GP G
Sbjct: 1109 PVGLPGPAGP------AGSPGEDGDKGEIGEPGQKGS---KGDKGENGPPGPPGLQGPVG 1159

Query: 666  PKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSG 725
              G  G  G+PGP G  G  G+ G  G  G+PG  GP G  G PG PG  GE G  G  G
Sbjct: 1160 APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMG 1219

Query: 726  KSGPRGERGPTGPRGQRGPRGATGKSGA------KGTSGGDGPHGPPGERGLPGPQGPNG 779
              GP G RGP GP G  GP+G  G  G+      KG  G  G  GPPGE G+ GP+G  G
Sbjct: 1220 PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERG 1279

Query: 780  FPGPKGPP---GPPGKDGLPGHPGQRGE---VGFQGKTGPPGPPGVVGPQGAAGETGPMG 833
              G  GPP   GPPG  G PG  G +G    VGF G  GPPG PG  G  G  G+ G  G
Sbjct: 1280 EKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDG 1339

Query: 834  ERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPG 893
            + G PGPPGP GE             G PGPPG  G  G AG  G  GE+G  G AG  G
Sbjct: 1340 DPGQPGPPGPSGE------------AGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEG 1387

Query: 894  LKGNEGPSGPPGPAGSPGERGAAGSGGPIGP---PGRPGPQGPPGAAGEKGVPGEKGPIG 950
              G  GP GP GPAG PG  G  G  GP+G    PG  G  GPPG  G  G+PG KG  G
Sbjct: 1388 PPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPG 1447

Query: 951  PTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVG 1010
              G  G  G +GL GP G  G      +KG+ G PG +G+ G KG+ G PGP GP+GP G
Sbjct: 1448 SKGEKGHPGLIGLIGPPGEQG------EKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPG 1501

Query: 1011 QPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIG--LQGLPGPSGEK 1060
             PG  G  G  G +G  G  G KGD G  G  G PGP G  +Q LP  S +K
Sbjct: 1502 PPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKK 1553



 Score =  365 bits (936), Expect = e-100
 Identities = 223/525 (42%), Positives = 255/525 (48%), Gaps = 92/525 (17%)

Query: 960  PVGLPGPAGPPGVAGE-DGDKGEVGDPGQKGTKGNKGE----------HGPPGPPGP--- 1005
            P   P     PGV  E D  +  +   G  G KG KGE           GPPGP GP   
Sbjct: 393  PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 452

Query: 1006 IGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRG------------------------- 1040
            +GP G  G  G  G+PG RGP G  G  G +G  G                         
Sbjct: 453  MGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQ 512

Query: 1041 --------------FNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR---GPAGP 1083
                            GPPGP+GL G PGP G  G +G  G  G PGP GPR   GP GP
Sbjct: 513  EAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGP 572

Query: 1084 NGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP----- 1138
             G  G +G PG  G  G PGE G  G+ G  G+ G PG KG RGERG +G  G P     
Sbjct: 573  TGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGM 632

Query: 1139 -GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGS 1197
             GE G  GP+G  G+ GP+G  GP G PG PG PG  G  G  G KG+ G  GEPG PG 
Sbjct: 633  RGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQ 692

Query: 1198 ---------PGPTGENGPP---GPLGKRGPAGSPGSE---GRQGGKGAKGDPGAIGAPGK 1242
                     PGP G  GPP   GP GK G AG PG++   G  G +G  G+ GA+G PG 
Sbjct: 693  QGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGP 752

Query: 1243 TGPVGPAGPAGKPGPDGLRGLPGSVGQQGR---PGATGQAGPPGPVGPPGLPGLRGDAGA 1299
             GP+G  GP G  G DG+RGL GS G++G    PG  G  G  G  G  G  G RG+ G 
Sbjct: 753  QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGP 812

Query: 1300 KGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQ---KGEMGIP---------GASGP 1347
            +G KG  G  G  GP G+ GEKG  G+PG  G PG+   KG  G P         GA G 
Sbjct: 813  EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV 872

Query: 1348 IGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGE 1392
             G  GP G  GP GP+G++GA GP G  G KG  G  G PGPPGE
Sbjct: 873  AGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGE 917



 Score =  240 bits (613), Expect = 7e-63
 Identities = 113/230 (49%), Positives = 166/230 (72%), Gaps = 8/230 (3%)

Query: 28  GAPPVDVLRALRFPSLPDGVRRAKGICP-------ADVAYRVARPAQLSAPTRQLFPGG- 79
           GA PVDVL+AL F + P+G+ +  G C        +D AYRV++ AQLSAPT+QLFPGG 
Sbjct: 35  GAAPVDVLKALDFHNSPEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGT 94

Query: 80  FPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPVRFLYEDQTGRPQPPSQPVF 139
           FP+DFS+L  V+ + G+Q+ LL++Y+  G++Q+G+E+GR   FL+ED TG+P P   P+F
Sbjct: 95  FPEDFSILFTVKPKKGIQSFLLSIYNEHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLF 154

Query: 140 RGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSARPVLDTHGVIIFGARILDEE 199
           R +++ADGKWHRVA++V+ ++VT+IVDCKK+ T+PL RS R ++DT+G+ +FG RILDEE
Sbjct: 155 RTVNIADGKWHRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEE 214

Query: 200 VFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQPHRAQRSPQ 249
           VFEGD+Q+  I    +AAY+ CE    +C+    +  Q Q+P   + +P+
Sbjct: 215 VFEGDIQQFLITGDPKAAYDYCEHYSPDCDSSAPKAAQAQEPQIDEYAPE 264



 Score =  233 bits (594), Expect = 1e-60
 Identities = 136/307 (44%), Positives = 153/307 (49%), Gaps = 47/307 (15%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPP---GIQGNPGPVGDPG 319
            P      GP+G +GEKGE           GPPG  GP G  GPP   G +GNPGPVG PG
Sbjct: 1266 PGEAGVGGPKGERGEKGE----------AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPG 1315

Query: 320  ERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALR 379
            + GPPG  G  G DG  G  G             G  GP   + EA              
Sbjct: 1316 DPGPPGEPGPAGQDGVGGDKGED--------GDPGQPGPPGPSGEA-------------- 1353

Query: 380  GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPR------GPQGLTGPPGKAGRRGRA 433
            GPPGP G  G PG  G  G  G KG  G+ G +GP       GPQG  G PG  G RG  
Sbjct: 1354 GPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIP 1413

Query: 434  GADGARGMP------GDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDD 487
            G  G +G+P      G PG  G  G  GL G PG KG +G  G  GL GPPGE GE+GD 
Sbjct: 1414 GPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDR 1473

Query: 488  GEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTP 547
            G  G +G PG  G  G+ GP GP G PGPPG+ G  GP+G KGS GP G+ G  G  G P
Sbjct: 1474 GLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPP 1533

Query: 548  GTQGLPG 554
            G+ G PG
Sbjct: 1534 GSPGPPG 1540


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score = 1771 bits (4586), Expect = 0.0
 Identities = 853/1391 (61%), Positives = 986/1391 (70%), Gaps = 56/1391 (4%)

Query: 273  GLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGS 332
            G KG KGEPAV+E G   EGPPG  GP G++GP G  G PG  GDPG  GP G  G+PG 
Sbjct: 373  GEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGI 432

Query: 333  DGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPG 392
            DG  GPPGT +M+PF+F +GG  KGP V+ Q+AQAQA+LQQ +L+++GPPGP+G TGRPG
Sbjct: 433  DGIRGPPGTVIMMPFQF-AGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPG 491

Query: 393  PLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRG 452
            P+G PG PGLKGE G  GPQGPRG QG  GPPG+ G+ GR GADGARG+PGD G KGDRG
Sbjct: 492  PVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRG 551

Query: 453  FDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPG 512
            FDGLPGLPGEKG RGD G  G PGPPGEDGERG +G  GP G  GE GPRGLLGP+G PG
Sbjct: 552  FDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPG 611

Query: 513  IPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPG 572
              G PGV G+DG  G KG++GP GEPGPPGQQG  G+QGLPGPQG IG  GEKGP G PG
Sbjct: 612  PTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPG 671

Query: 573  LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 632
            +PG+PGSDGP GHPG EGP G KG QGP G  GP GYPGPRGVKG  G RGL+G KGEKG
Sbjct: 672  IPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKG 731

Query: 633  EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 692
            EDGFPGFKGD+G+KGD+G+ G PG RGEDGPEGPKG+ G  G+ GPPG  GEKGKLGVPG
Sbjct: 732  EDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPG 791

Query: 693  LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG 752
            LPGYPGR GPKGS+GFPG  G  GEKG  G +G+ G  GERGP G RG+RG  GATG+ G
Sbjct: 792  LPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPG 851

Query: 753  AKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTG 812
             KG  G DG  G PGE+GLPG QGP GFPGPKGPPG  GKDG PGHPGQRGE+GFQG+TG
Sbjct: 852  PKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTG 911

Query: 813  PPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDG 872
            PPGP GV+GPQG  GE GP+GERG PGPPGPPGEQGLPG  G+EG KG+ GPPG  GK+G
Sbjct: 912  PPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEG 971

Query: 873  PAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQG 932
            PAGLRGFPG +G PG  G  GLKG++GP GP G  GSPGERG  G  G IG PG+ G +G
Sbjct: 972  PAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEG 1031

Query: 933  PPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKG 992
            P G AG+KG  GE+GP GPTG+DG+ GP+G  GP G  G +GE+GDKG+VG PG KG+KG
Sbjct: 1032 PVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKG 1091

Query: 993  NKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQG 1052
            +KG+ GPPG PG  GP G PG  GADG  G RGP G FG KGD+G RGF G  GP GLQG
Sbjct: 1092 DKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQG 1151

Query: 1053 LPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESG 1112
            LPGP GEKGE GDVG MGP G PGPRGP GP G++G  G PGGVG  G  GEKGE G++G
Sbjct: 1152 LPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAG 1211

Query: 1113 SPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG 1172
             PG  G PG+ GP+G+ GEKG+SG  G  GPPG KGP G+DG KG+ GP G PGD GPPG
Sbjct: 1212 DPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPG 1271

Query: 1173 EGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKG 1232
            + G  G DG+ G++G+ G+ G PG PG +GE G PGP GKRGP+G  G EGR+G KGAKG
Sbjct: 1272 DPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKG 1331

Query: 1233 DPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG 1292
            +PG  G PG+TGP+G  GP G+ GP+GLRG+PG VG+ G  GA GQ GPPGP+GP GLPG
Sbjct: 1332 EPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPG 1391

Query: 1293 LRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGG 1352
            L+GD G KGEKGH GLIGLIGPPGE GEKGD+GLPG QG PG KG+ G PG  G +G  G
Sbjct: 1392 LKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPG 1451

Query: 1353 PPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGS 1412
            PPG+ GP G KG+KG+ G  GP+G+ G  GPPG PG P E                + G 
Sbjct: 1452 PPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAPAE----------------LHGL 1495

Query: 1413 RLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHP 1472
            R  +    +P    P   GGLEE+  SL SL  E+EQ+RRP GT + P   C +L   HP
Sbjct: 1496 RRRRRFVPVP---LPVVEGGLEEVLASLTSLSLELEQLRRPPGTAERPGLVCHELHRNHP 1552

Query: 1473 ELPDGEYWVDPNQGCARDAFRVFCNFTAGGETCVTPRDDV-------------------- 1512
             LPDGEYW+DPNQGCARD+FRVFCNFTAGGETC+ P                        
Sbjct: 1553 HLPDGEYWIDPNQGCARDSFRVFCNFTAGGETCLYPDKKFEIVKLASWSKEKPGGWYSTF 1612

Query: 1513 ---TQFSYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPCSGAAR---------DGPLRLR 1560
                +FSYVD++GSPV VVQL FL+LLS +A Q+ +Y C  AA              R  
Sbjct: 1613 RRGKKFSYVDADGSPVNVVQLNFLKLLSATARQNFTYSCQNAAAWLDEATGDYSHSARFL 1672

Query: 1561 GANEDELS--PETSPYVKEFRDGCQTQQG--RTVLEVRTPVLEQLPVLDASFSDLGAPPR 1616
            G N +ELS    T+  V   +DGC+ ++G  +T+ E  +     LP+ D + +D G   +
Sbjct: 1673 GTNGEELSFNQTTAATVSVPQDGCRLRKGQTKTLFEFSSSRAGFLPLWDVAATDFGQTNQ 1732

Query: 1617 RGGVLLGPVCF 1627
            + G  LGPVCF
Sbjct: 1733 KFGFELGPVCF 1743



 Score =  790 bits (2041), Expect = 0.0
 Identities = 466/1032 (45%), Positives = 525/1032 (50%), Gaps = 120/1032 (11%)

Query: 262  EPQSQAAHGPRGLKGEKGEPAVL----EPG----MLVEGPPGPEGPAGLIGPPGIQGNPG 313
            E  ++   GPRGL+G  G P  +     PG      + G  GP+G  G  G PG+ G  G
Sbjct: 504  EEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKG 563

Query: 314  PVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQ 373
              GD G  G PG  G  G  GA GPPG +           G+ GP              +
Sbjct: 564  QRGDFGHVGQPGPPGEDGERGAEGPPGPT--------GQAGEPGP--------------R 601

Query: 374  ARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRA 433
              L  RG PGP   TGRPG  G  G+PG KG  G  G  GP G QG  G  G  G +G  
Sbjct: 602  GLLGPRGSPGP---TGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLI 658

Query: 434  GADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLP---GPPGEDGERGDDGEI 490
            G  G +G PG+PG+ G  G DG  G PG +G  G+ GAQG P   GPPG  G RG  G  
Sbjct: 659  GTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTS 718

Query: 491  GPRGLPGESGPRGL---------LGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP 541
            G RGL GE G +G          +G KG  G PG PG RG DGP+GPKG  G  GE GPP
Sbjct: 719  GNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPP 778

Query: 542  GQ---------QGTPGTQGLPGPQGAI------GPHGEKGPQGKPGLPGMPGSDGPPGHP 586
            G           G PG  G PGP+G+I      GP GEKG  GK G PG+ G  GPPG  
Sbjct: 779  GSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSR 838

Query: 587  GKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIR------GLKGHKGEKGEDGFPGFK 640
            G+ G PG  G  GP G  G  G PG  G KG+ G++      G KG  G +G+DG PG  
Sbjct: 839  GERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHP 898

Query: 641  GDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGL------- 693
            G  G  G +G+ G PG  G  GP+G  G  GP G+ GPPG  G  G+ G+PGL       
Sbjct: 899  GQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAK 958

Query: 694  -----PGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGAT 748
                 PG  G++GP G  GFPG  G  G+ G  GL G  GP G  G  G  G+RGP G  
Sbjct: 959  GELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPA 1018

Query: 749  GKSGAKGTSGGDGPHGPP------GERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQR 802
            G  G  G SG +GP GP       GERG PGP G +G PGP GP GPPG  G  G  G +
Sbjct: 1019 GGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDK 1078

Query: 803  GEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP 862
            G+VG  G  G  G  G  GP G  G  GP    GHPGPPG  G QG  G  G  G KGD 
Sbjct: 1079 GDVGAPGHKGSKGDKGDAGPPGQPGIRGP---AGHPGPPGADGAQGRRGPPGLFGQKGDD 1135

Query: 863  GPPGAPGKDGPAGLRGF---PGERGLPGTAGGPGLKGNEGPSGPPGPAGS---PGERGAA 916
            G  G  G  GP GL+G    PGE+G  G  G  G  G  GP GP GP GS   PG  G  
Sbjct: 1136 GVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGV 1195

Query: 917  GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPP------ 970
            G  G +G  G  G  G PG  G  G+PG KG IG  G  G  G  G PG  GPP      
Sbjct: 1196 GQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAK 1255

Query: 971  ---GVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQ 1027
               G  G  GD G  GDPG  G  G+ GE G PG  G  GP G  G  GA G PG RGP 
Sbjct: 1256 GSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPS 1315

Query: 1028 GHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGAD 1087
            GH G +G EG +G  G PGP G  G  GP G +G  G VGP G  G PGP G  G  GA 
Sbjct: 1316 GHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAP 1375

Query: 1088 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK 1147
            G  GPPG +G  G PG KG+ G  G  G  G  G+ GP GE GEKG+ G PG  GPPGPK
Sbjct: 1376 GQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPK 1435

Query: 1148 GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPP 1207
               GD GP   PGP+G  G PGPPG  GP GQ G+K         G PGS GP G+ GP 
Sbjct: 1436 ---GDPGP---PGPIGSLGHPGPPGVAGPLGQKGSK---------GSPGSMGPRGDTGPA 1480

Query: 1208 GPLGKRGPAGSP 1219
            GP    GP G+P
Sbjct: 1481 GP---PGPPGAP 1489



 Score =  689 bits (1777), Expect = 0.0
 Identities = 412/917 (44%), Positives = 469/917 (51%), Gaps = 91/917 (9%)

Query: 259  QNQEPQSQAAHGPRGLKGEKGEPAVL----EPGMLVE-GPPGPEGPAGLIGPPGIQGNPG 313
            Q  EP  +   GPRG  G  G P V      PG     GPPG  GP G  G  G QG PG
Sbjct: 594  QAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPG 653

Query: 314  P---VGDPGERGPPGR---AGLPGSDGAPGPPGTSLMLPFRFGSG-GGDKGPV------- 359
            P   +G PGE+GPPG     GLPGSDG  G PG       +   G  G  GP        
Sbjct: 654  PQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRG 713

Query: 360  VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 419
            V           ++      G PG  G  G  G  G+PG+PG +GE G  GP+G  G  G
Sbjct: 714  VKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAG 773

Query: 420  LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLP---G 476
              GPPG AG +G+ G  G  G PG PG KG  GF G  G  GEKG  G TG  GL    G
Sbjct: 774  EEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERG 833

Query: 477  PPGEDGERGD---DGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLG 533
            PPG  GERG     G+ GP+G  G+ G  G+ G KG PG+ GPP   G  GP+GP G  G
Sbjct: 834  PPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPP---GFPGPKGPPGHQG 890

Query: 534  PQGEPGPPGQQGTPGTQGL---PGPQGAIGPH---GEKGPQGKPGLPGMPGSDGPPGHPG 587
              G PG PGQ+G  G QG    PGP G +GP    GE GP G+ G PG PG  G  G PG
Sbjct: 891  KDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPG 950

Query: 588  KEGPPGTKGNQGPSGP---QGPL---GYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKG 641
             EG  G KG  GP GP   +GP    G+PGP+G  G  G  GLKG KG  G  G  G  G
Sbjct: 951  LEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPG 1010

Query: 642  DIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPP------GLMGEKGKLGVPGLPG 695
            + G  G  G +G+PG  G +GP GP G+ G  G+ GPP      G+ G  G LG PG  G
Sbjct: 1011 ERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAG 1070

Query: 696  YPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGP------RGQRGPRGATG 749
              G +G KG +G PG  G+ G+KG  G  G+ G RG  G  GP      +G+RGP G  G
Sbjct: 1071 PSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFG 1130

Query: 750  KSGAKGTSGGDGPHGPPGERGLPGP------------QGPNGFPGPKGPPGPPGKDGLPG 797
            + G  G  G  G  GPPG +GLPGP             GP+G PGP+GP GP G +G PG
Sbjct: 1131 QKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPG 1190

Query: 798  HP---------GQRGEVGFQGKTGPPGPPGVVGPQGAAGE---TGPMGERGHPGPPGPPG 845
             P         G++GE G  G  GPPG PG+ GP+G  GE   +GP G  G PG  GPPG
Sbjct: 1191 LPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPG 1250

Query: 846  EQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGG---PGLKGNEGPSG 902
            E G  G+ G  G  GD GPPG P   G +G+ G PGE+G PG  GG   PG  G  G  G
Sbjct: 1251 EDGAKGSVGPTGLPGDLGPPGDP---GVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPG 1307

Query: 903  PPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVG 962
            PPG  G  G  G  G  G  G  G PGP GPPG  G  G  G  G +GP G  G+ GPVG
Sbjct: 1308 PPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVG 1367

Query: 963  LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPG 1022
             PG  G PG  G  G  G  G PG KG  G KGE G  G  G IGP G+ G  G  G PG
Sbjct: 1368 EPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPG 1427

Query: 1023 ARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAG 1082
             +GP    G KGD       GPPGPIG  G PGP G  G  G  G  G PG  GPRG  G
Sbjct: 1428 VQGPP---GPKGDP------GPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTG 1478

Query: 1083 PNGADGPQGPPGGVGNL 1099
            P G  GP G P  +  L
Sbjct: 1479 PAGPPGPPGAPAELHGL 1495



 Score =  490 bits (1261), Expect = e-138
 Identities = 300/703 (42%), Positives = 352/703 (50%), Gaps = 96/703 (13%)

Query: 257  RPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVG 316
            R +  +P +    GP+G  G+ G P +  PG   +G PG +GP G  GP G  G+ G  G
Sbjct: 838  RGERGQPGATGQPGPKGDVGQDGAPGI--PG--EKGLPGLQGPPGFPGPKGPPGHQGKDG 893

Query: 317  DPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--GDKGPVVAAQEAQAQAILQQA 374
             PG  G  G  G  G  G PGP G         G  G  G+ GP                
Sbjct: 894  RPGHPGQRGELGFQGQTGPPGPAGV-------LGPQGKTGEVGP---------------- 930

Query: 375  RLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAG 434
             L  RGPPGP      PGP G+ G PGL+G  G  G  GP GP G  GP   AG RG  G
Sbjct: 931  -LGERGPPGP------PGPPGEQGLPGLEGREGAKGELGPPGPLGKEGP---AGLRGFPG 980

Query: 435  ADGARGMPGDPGVKGDRGFD---GLPGLPGEKGHRGDTGAQGLP------GPPGEDGERG 485
              G  G PG  G+KGD+G     G  G PGE+G  G  G  GLP      GP G  G++G
Sbjct: 981  PKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKG 1040

Query: 486  DDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV---RGMDGPQGPKGSLGPQGEPGPPG 542
              GE GP G  G+ G  G LGP GPPG  GP G    +G  G  G KGS G +G+ GPPG
Sbjct: 1041 SRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPG 1100

Query: 543  QQGTPGTQGLPGPQGAIGPHGEKGP------QGKPGLPGMPGSDGPPGHPGKEGPPGTKG 596
            Q G  G  G PGP GA G  G +GP      +G  G+ G  G  GPPG  G  GPPG KG
Sbjct: 1101 QPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKG 1160

Query: 597  NQGPSGPQGPLGYPGPRGVKGVDGIRGLK------------GHKGEKGE---------DG 635
              G  G  GP G PGPRG +G  G  G              G KGE+G+          G
Sbjct: 1161 EVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPG 1220

Query: 636  FPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPG 695
             PG KGDIG KGD G  G  G  G+ GP G  G  G  G  G PG +G  G  GV G+ G
Sbjct: 1221 IPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDG 1280

Query: 696  YPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKG 755
             PG +G  G +G PG PGASGE GA G  GK GP G  G  G  G++G +G  G  G  G
Sbjct: 1281 SPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPG 1340

Query: 756  TSGGDGPHGPPGE------RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQG 809
             +G  G  GPPG       RG+PGP G  G  G  G  GPPG  G  G PG +G+ G +G
Sbjct: 1341 RTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKG 1400

Query: 810  KTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG 869
            + G  G  G++GP G AGE    G++G PG  GPPG +G PG  G  G+ G PGPPG  G
Sbjct: 1401 EKGHIGLIGLIGPPGEAGE---KGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAG 1457

Query: 870  KDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGE 912
              G  G +G PG           G +G+ GP+GPPGP G+P E
Sbjct: 1458 PLGQKGSKGSPGSM---------GPRGDTGPAGPPGPPGAPAE 1491



 Score =  449 bits (1155), Expect = e-125
 Identities = 286/674 (42%), Positives = 327/674 (48%), Gaps = 119/674 (17%)

Query: 847  QGLPGTAGKEGTKGDP----------GPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKG 896
            Q  PG AG++G KG+P          GPPGAPG  G                     + G
Sbjct: 367  QIFPG-AGEKGAKGEPAVIEKGQQFEGPPGAPGPQG---------------------VVG 404

Query: 897  NEGP---------SGPPGPAGSPGERGAAGSGGP----------------IGPP------ 925
              GP          GPPGPAG PG  G  G  GP                 GPP      
Sbjct: 405  PSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQA 464

Query: 926  --------------GRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPG 971
                          G PGP G  G  G  G+PG  G  G  G +G QGP GL GP GPPG
Sbjct: 465  QAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPG 524

Query: 972  VAGE---DGDKGEVGDPGQKGTKGNKGEHGPPGPP------GPIGPVGQPGAAGADGEPG 1022
              G+    G  G  G PG  G KG++G  G PG P      G  G VGQPG  G DGE G
Sbjct: 525  RVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERG 584

Query: 1023 ARGPQGHFGAKGDEGTRGFNGP---PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG 1079
            A GP G  G  G+ G RG  GP   PGP G  G+ G  G  G  G+VGP G PGPPG +G
Sbjct: 585  AEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQG 644

Query: 1080 PAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPG 1139
              G  G  GPQG  G  G  GPPG  G PG  GS G  G PG +GP GE+G +G  G  G
Sbjct: 645  NHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAG 704

Query: 1140 EPGPPGPKGPTGD------DGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1193
             PG PGP+G  G        G KG  G  GFPG  G  G  G +G+ GA G RGEDG  G
Sbjct: 705  PPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEG 764

Query: 1194 QPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAG 1253
              G  G  GE GPPG  G++G  G PG  G  G  G K   G+IG PG  GP+G  G +G
Sbjct: 765  PKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPK---GSIGFPGPLGPIGEKGKSG 821

Query: 1254 K---PGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIG 1310
            K   PG +G RG PGS G++G+PGATGQ GP G VG  G PG+ G+ G  G +G PG  G
Sbjct: 822  KTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPG 881

Query: 1311 LIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGAS------------GPIGPGGPPGLPG 1358
              GPPG QG+ G  G PG +G  G +G+ G PG +            GP+G  GPPG PG
Sbjct: 882  PKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPG 941

Query: 1359 PAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQED 1418
            P G +G  G  G  G KGE G  GP G  GP G    P P     K      G   ++ D
Sbjct: 942  PPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGP-----KGGPGDPGPTGLKGD 996

Query: 1419 EAIP-TGGAPGSPG 1431
            +  P   GA GSPG
Sbjct: 997  KGPPGPVGANGSPG 1010



 Score =  179 bits (454), Expect = 2e-44
 Identities = 139/413 (33%), Positives = 165/413 (39%), Gaps = 89/413 (21%)

Query: 1066 VGPMGPPGPPGPRGPAGPNGADGPQGPPGG-------VGNLGPPGEKGE--------PGE 1110
            V P G P  P PR      G    +G  G        +    PP +  E          E
Sbjct: 233  VAPQGEPETPRPRRKGKGKGRKKGRGRKGKGRKKNKEIWTSSPPPDSAENQTSTDIPKTE 292

Query: 1111 SGSPGIQGEP-----------GVKGPRGERGEKGESG-----------QPGEPGPPGPKG 1148
            + +P +   P           G+     ER    +SG           +  E G     G
Sbjct: 293  TPAPNLPPTPTPLVVTSTVTTGLNATILERSLDPDSGTELGTLETKAAREDEEGDDSTMG 352

Query: 1149 PTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGA--KGDR--GEDGEPGQPGSPGPTGEN 1204
            P  D      P    F   PG  GE G +G+     KG +  G  G PG  G  GP+G  
Sbjct: 353  P--DFRAAEYPSRTQFQIFPGA-GEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPP 409

Query: 1205 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAI--------------------------- 1237
            GPPG  G  GP G  G  G  G  G +G PG +                           
Sbjct: 410  GPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAV 469

Query: 1238 ---------GAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPP 1288
                     G PG  G  G  GP G PG  GL+G  G+ G QG  G  G  GPPG VG  
Sbjct: 470  LQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKM 529

Query: 1289 GLP------GLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIP 1342
            G P      GL GD G KG++G  GL GL G  G++G+ G  G PGP G  G++G  G P
Sbjct: 530  GRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPP 589

Query: 1343 GASGPIGPGGPPGLPGP---AGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGE 1392
            G +G  G  GP GL GP    GP G  G TG  G  G KG  GPPG PGPPG+
Sbjct: 590  GPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQ 642


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score = 1160 bits (3000), Expect = 0.0
 Identities = 656/1424 (46%), Positives = 770/1424 (54%), Gaps = 95/1424 (6%)

Query: 268  AHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA 327
            A G  G KG+KGEP  ++  +  +GPPGP+GPAG  GP G +G+ G  G PG RG  G  
Sbjct: 96   ASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 155

Query: 328  GLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQA---QAILQQARLALRGPPGP 384
            G PG+ G PGPPG     P   G GG     +    + +A   Q  + Q  +   GP GP
Sbjct: 156  GTPGNPGPPGPPGP----PGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGP 211

Query: 385  MGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGD 444
             G  G PGP G  G+PG  GE G  GP GPRGP G   PPGK G  G AG  G  G  G 
Sbjct: 212  PGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPG---PPGKPGDDGEAGKPGKAGERGP 268

Query: 445  PGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGL 504
            PG +G RGF G PGLPG KGHRG  G  G  G  G  G +G+ G  G  G PG  GPRGL
Sbjct: 269  PGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGL 328

Query: 505  LGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGE 564
             G +G  G  G  G RG DG  GP G  GP G  G PG  G PG +G  GP GA GP G 
Sbjct: 329  PGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGA 388

Query: 565  KGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGL 624
            +GP+G+PG PG PG  G  G+PG +G PG KG+ G  G  G  G+PGPRG  G  G  G 
Sbjct: 389  QGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGP 448

Query: 625  KGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGE 684
             G KG+ GE G  GFKG+ G KG+ G  G  G+ G  G EG +G  G  G  GP G  GE
Sbjct: 449  LGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGE 508

Query: 685  KGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG---ERGPTGPRGQ 741
            +G  G  G PG  G  GPKG+ G  G  G +G KGA G  G+ G  G    RG TG  G 
Sbjct: 509  RGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGD 568

Query: 742  RGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK---DGLPGH 798
             GP+G  G SGA G  G  GP GP G RG PG  G   FPGPKG  G PGK    GLPG 
Sbjct: 569  AGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMG---FPGPKGANGEPGKAGEKGLPGA 625

Query: 799  PGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG---PMGERGHPGPPGPPGEQGLPGTAGK 855
            PG RG  G  G+TG  GPPG  GP G  GE G   P G +G PGPPGPPGE       GK
Sbjct: 626  PGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGE------GGK 679

Query: 856  EGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGA 915
             G +G PG  GAPG  GP G RGFPGERG PG  G  G +G  G  G  GP G+ G  G 
Sbjct: 680  PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGP 739

Query: 916  AGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE 975
             G+ GP G  G PG +G  G AG KG  G+ G  GP G  G  G  GL GP GPPG AG 
Sbjct: 740  PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 799

Query: 976  DGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGD 1035
            +G+KGEVG PG  G+ G +G  G  G  GP GP G  G  GADG+PGA+G QG  G KGD
Sbjct: 800  NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGD 859

Query: 1036 EGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGG 1095
             G  G  GP G  G QG  G +G KG  G  GP G  G PG  G  GP G++G  GPPG 
Sbjct: 860  AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP 919

Query: 1096 VGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG---ERGEKGESGQPGEPGPPGPKGPTGD 1152
             G  G  G KG  G+SG PG  GEPG++GP G   E+GE G+ G  G  GPPGP+G  G 
Sbjct: 920  PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ 979

Query: 1153 DGPKGNPGPVG---FPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP 1209
             G  G PG  G   FPG PGP GE G +G  GA GDRG  G  G PG  GP GE   PG 
Sbjct: 980  RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGE---PGR 1036

Query: 1210 LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQ 1269
             G  G  G PG +G  G KG +G+ GA+GAPG  GP G  GPAG  G  G RG  G+ G 
Sbjct: 1037 EGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1096

Query: 1270 QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP 1329
             G  G  G  G  GP GP G  G  G+ G +G KGH G  GL G PG  G  GD+G  GP
Sbjct: 1097 MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP 1156

Query: 1330 QGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGP 1389
             G  G +G    PG  GP G  G  G+PGP GP G +G +G  GP G  G  GPPG PGP
Sbjct: 1157 AGPSGPRGP---PGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGP 1213

Query: 1390 PGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLE----EIFGSLDSLRE 1445
            PG  I            +  D  + M+ D+A          GGL     E+  +L SL  
Sbjct: 1214 PGPGIDMSAFAGLGPREKGPDPLQYMRADQAA---------GGLRQHDAEVDATLKSLNN 1264

Query: 1446 EIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGETC 1505
            +IE +R P G++ +PARTC+DLKLCHPE   G+YW+DPNQGC  DA +VFCN    GETC
Sbjct: 1265 QIESIRSPEGSRKNPARTCRDLKLCHPEWKSGDYWIDPNQGCTLDAMKVFCNMET-GETC 1323

Query: 1506 VTPR--------------------------DDVTQFSYVDSEGSP-VGVVQLTFLRLLSV 1538
            V P                           +    FSY D   +P    VQ+TFLRLLS 
Sbjct: 1324 VYPNPANVPKKNWWSSKSKEKKHIWFGETINGGFHFSYGDDNLAPNTANVQMTFLRLLST 1383

Query: 1539 SAHQDVSYPCSGAAR---------DGPLRLRGANEDELSPETSP--YVKEFRDGCQT--- 1584
               Q+++Y C  +              L ++G+N+ E+  E +        +DGC     
Sbjct: 1384 EGSQNITYHCKNSIAYLDEAAGNLKKALLIQGSNDVEIRAEGNSRFTYTALKDGCTKHTG 1443

Query: 1585 QQGRTVLEVRTPVLEQLPVLDASFSDLGAPPRRGGVLLGPVCFM 1628
            + G+TV+E R+    +LP++D +  D+G P +  GV +GPVCF+
Sbjct: 1444 KWGKTVIEYRSQKTSRLPIIDIAPMDIGGPEQEFGVDIGPVCFL 1487



 Score =  882 bits (2278), Expect = 0.0
 Identities = 523/1162 (45%), Positives = 579/1162 (49%), Gaps = 163/1162 (14%)

Query: 266  QAAHGPRGLKGEKGEPAVL----EPGMLVEGPPGPEGPAGLIGPPGIQGN---------- 311
            Q   G RG KGEKG P       EPG    G PGP GP G  GPPG+ GN          
Sbjct: 131  QGPRGDRGDKGEKGAPGPRGRDGEPG--TPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFD 188

Query: 312  -----------PGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--GDKGP 358
                        GP+G  G RGPPG AG PG  G  G PG         G  G  G  GP
Sbjct: 189  EKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEP-------GEPGVSGPMGP 241

Query: 359  VVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQ 418
                                RGPPGP    G+PG  G+ G PG  GE G  GPQG RG  
Sbjct: 242  --------------------RGPPGP---PGKPGDDGEAGKPGKAGERGPPGPQGARGFP 278

Query: 419  GLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPP 478
            G  G PG  G RG  G DGA+G  G PGVKG+ G  G  G PG  G RG  G +G  GP 
Sbjct: 279  GTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPA 338

Query: 479  GEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGI---PGPPGVRGMDGPQGPKGSLGPQ 535
            G  G RG+DG+ GP G PG  GP G  G  G PG     GP G RG +G QGP+G  G  
Sbjct: 339  GAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTP 398

Query: 536  GEPGPPGQQGTPGTQGL------------------------PGPQGAIGPHGEKGPQGKP 571
            G PGP G  G PGT G+                        PGPQGA GP G KG  G+P
Sbjct: 399  GSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEP 458

Query: 572  GLPGMPGSDGPPGHPGKEGPPGT---------------KGNQGPSGPQGPLGYPGPRGVK 616
            G+ G  G  GP G PG  GP G                 G  GP GP G  G PG RG  
Sbjct: 459  GIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFP 518

Query: 617  GVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSR---GEDGPEGPKGRTGPT 673
            G DG+ G KG  GE+G  G  G KG  G  G  GE G+PG+R   G  G  GP+G+ GP+
Sbjct: 519  GQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPS 578

Query: 674  ------GDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKS 727
                  G PGPPG  G +G+ GV G PG  G  G  G  G  G PGA G +G  G  G++
Sbjct: 579  GAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGET 638

Query: 728  GPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPP 787
            G  G  GP GP G+RG +GA G SG +G     GP GPPGE G PG QG  G  G  G  
Sbjct: 639  GAAGPPGPAGPAGERGEQGAPGPSGFQGL---PGPPGPPGEGGKPGDQGVPGEAGAPGLV 695

Query: 788  GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ 847
            GP G+ G PG  G  G  G QG  G PG PG  GP+GA+G  GP G +G PG  G PGE+
Sbjct: 696  GPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGER 755

Query: 848  GLPGTAGKEGTKGD---PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPP 904
            G  G AG +G +GD    GP GAPGKDG    RG  G  G PG AG     G +G  GPP
Sbjct: 756  GAAGIAGPKGDRGDVGEKGPEGAPGKDGG---RGLTGPIGPPGPAGA---NGEKGEVGPP 809

Query: 905  GPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGE---KGVPGEKGPIGPTGRDGVQGPV 961
            GPAGS G RGA G  G  GPPG  G  GPPGA G+   KG  GE G  G  G  G QGP 
Sbjct: 810  GPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPS 869

Query: 962  GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP------PGPPGPIGPVGQPGAA 1015
            G PGP GP GV G  G +G  G PG  G  G  G  GP      PGPPGP GP G+ G  
Sbjct: 870  GAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPK 929

Query: 1016 GA---------DGEPGARGPQGHFGAK---GDEGTRGFNGPPGPIGLQ------GLPGPS 1057
            GA          GEPG +GP G  G K   GD+G  G  GPPGP GL       GLPG  
Sbjct: 930  GARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQR 989

Query: 1058 GEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQ 1117
            GE+G  G  GP G PG  G  G +G  G  GP GPPG  G  G PG +G PG  G PG  
Sbjct: 990  GERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRD 1049

Query: 1118 GEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPR 1177
            G  GVKG RGE G  G  G PG PG PGP GPTG  G +G  G  G  G  GP G  G +
Sbjct: 1050 GAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQ 1109

Query: 1178 GQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAI 1237
            G  G +GD+GE GEPG+ G  G  G  G  G  G  GP+G  G+ G  G  G +G PG +
Sbjct: 1110 GPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPV 1169

Query: 1238 GAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGP------------- 1284
            G  GK G  G  GP G PGP G  G  G  G  G PG  G  GPPGP             
Sbjct: 1170 GPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPR 1229

Query: 1285 -VGPPGLPGLRGDAGAKGEKGH 1305
              GP  L  +R D  A G + H
Sbjct: 1230 EKGPDPLQYMRADQAAGGLRQH 1251



 Score =  816 bits (2109), Expect = 0.0
 Identities = 468/1038 (45%), Positives = 526/1038 (50%), Gaps = 124/1038 (11%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 322
            P    A GP+G +G  GEP   EPG  V GP GP GP G  G PG  G  G  G  GERG
Sbjct: 212  PGPAGAPGPQGFQGNPGEPG--EPG--VSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERG 267

Query: 323  PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAIL-QQARLALRGP 381
            PPG  G  G  G PG PG             G  G   A  EA A  +  +       G 
Sbjct: 268  PPGPQGARGFPGTPGLPGVK--------GHRGYPGLDGAKGEAGAPGVKGESGSPGENGS 319

Query: 382  PGPM------GYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGA 435
            PGPM      G  GR GP G  G+ G  G+ G  GP GP GP G  G PG  G +G AG 
Sbjct: 320  PGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP 379

Query: 436  DGAR---------------GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGE 480
             GAR               G PG  G  G+ G DG+PG  G  G  G  GA G PGP G 
Sbjct: 380  TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP 439

Query: 481  DGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEP-- 538
             G +G  G +GP+G  GE G  G  G +GP G PGP G +G  GP G +G  G +GEP  
Sbjct: 440  PGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGG 499

Query: 539  ----GPPGQQGTPGTQGLP---------------GPQGAIGPHGEKGPQGKPGLPGMPGS 579
                GPPG++G PG +G P               GP G  GP G  G  G+PG PG+PG+
Sbjct: 500  VGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGA 559

Query: 580  DGPPGHPGKEGP---------PGTKGNQGPSGPQGP------LGYPGPRGVKGVDGIRGL 624
             G  G PG  GP         PG  G  GP GPQG       +G+PGP+G  G  G  G 
Sbjct: 560  RGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGE 619

Query: 625  KGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGE 684
            KG  G  G  G PG  G+ G  G  G  G  G RGE G  GP G  G  G PGPPG  G+
Sbjct: 620  KGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGK 679

Query: 685  KGKLGVPGLPGYPGRQGPKGSLGFP---GFPGASGEKGARGL---SGKSGPRGERGPTGP 738
             G  GVPG  G PG  GP+G  GFP   G PGA G +G RGL    G  GP+G  GP GP
Sbjct: 680  PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGP 739

Query: 739  RGQRGPRGATGKSGAKGTSG-----GD-------GPHGPPGE---RGL------PGPQGP 777
             G +GP G  G  G +G +G     GD       GP G PG+   RGL      PGP G 
Sbjct: 740  PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 799

Query: 778  NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 837
            NG  G  GPPGP G  G  G PG+RGE G  G  G  GPPG  G  GA GE G  G++G 
Sbjct: 800  NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGD 859

Query: 838  PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 897
             G PGP G  G P   G +G  G  GP GA G  GP G  GFP   G  G  G PG  GN
Sbjct: 860  AGAPGPQGPSGAP---GPQGPTGVTGPKGARGAQGPPGATGFP---GAAGRVGPPGSNGN 913

Query: 898  EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGE------KGPIGP 951
             GP GPPGP+G  G +GA G  GP G  G PG QGP G  GEKG PG+      +GP GP
Sbjct: 914  PGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGP 973

Query: 952  TGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQ 1011
             G  G +G VGLPG  G  G  G  G  GE G  G  G  G++G  GP GPPG  GP G+
Sbjct: 974  QGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGE 1033

Query: 1012 PGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGP 1071
            PG  G+ G  G  G  G  G KGD G  G  G PG  G  G PGP+G  G+ GD G  G 
Sbjct: 1034 PGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGA 1093

Query: 1072 PGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGE 1131
             GP GP GPAG  G  GPQGP G  G  G PGE+G  G  G  G+QG PG  GP G++G 
Sbjct: 1094 QGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGA 1153

Query: 1132 KGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGE 1191
             G +G  G  GPPGP GP+G DG  G PGP+G P         GPRG+       GE G 
Sbjct: 1154 SGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPP---------GPRGRS------GETGP 1198

Query: 1192 PGQPGSPGPTGENGPPGP 1209
             G PG+PGP G  GPPGP
Sbjct: 1199 AGPPGNPGPPGPPGPPGP 1216



 Score =  743 bits (1919), Expect = 0.0
 Identities = 441/1029 (42%), Positives = 503/1029 (48%), Gaps = 102/1029 (9%)

Query: 229  EGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGM 288
            + G+R  P  Q       +P     + HR       ++   G  G+KGE G P       
Sbjct: 262  KAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPG------ 315

Query: 289  LVEGPPGPEGPAGL------IGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTS 342
               G PGP GP GL       GP G  G  G  G PG  GPPG  G  G  G PG PG  
Sbjct: 316  -ENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAK 374

Query: 343  LMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQP----- 397
                       G+ GP  A     AQ    +      G PGP G +G PG  G P     
Sbjct: 375  -----------GEAGPTGARGPEGAQG--PRGEPGTPGSPGPAGASGNPGTDGIPGAKGS 421

Query: 398  -GSPGLKGESGDLGPQGPRGPQGLT---GPPGKAGRRGRAGADGARGMPGDPGVKGDRGF 453
             G+PG+ G  G  GP+GP GPQG T   GP G+ G  G AG  G +G  G+PG  G +G 
Sbjct: 422  AGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGA 481

Query: 454  DGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGD------DGEIGPRGLPGESGPRGLLGP 507
             G  G  G++G RG+ G  G  GPPGE G  G+      DG  GP+G PGE GP GL GP
Sbjct: 482  PGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGP 541

Query: 508  KGP------PGIPGPPGVRGMD------GPQ---GPKGSLGPQGEPGPPGQQGT---PGT 549
            KG       PG PG PG RG+       GPQ   GP G+ G  G PGPPG QG    PG 
Sbjct: 542  KGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGV 601

Query: 550  QGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGY 609
             G PGP+GA   +GE G  G+ GLPG PG  G PG  G+ G  G  G  GP+G +G  G 
Sbjct: 602  MGFPGPKGA---NGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 658

Query: 610  PGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGR 669
            PGP G +G+ G  G  G  G+ G+ G PG  G  G+ G RGE G PG RG  G +G +G 
Sbjct: 659  PGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGP 718

Query: 670  TGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGAS------GEKGARGL 723
             G  G PG  G  G  G  G PG  G PG QG  G  G  G  G        GEKG  G 
Sbjct: 719  RGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGA 778

Query: 724  SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 783
             GK G RG  GP GP G  G  G  G+ G  G +G  G  G PGERG  GP GP GF GP
Sbjct: 779  PGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGP 838

Query: 784  KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 843
             G  G PG  G  G  GQ+G+    G  GP GP G  GPQG  G TGP G RG  GPPG 
Sbjct: 839  PGADGQPGAKGEQGEAGQKGDA---GAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGA 895

Query: 844  PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 903
             G  G  G  G  G+ G+PGPPG PG  G  G +G  G+ G PG AG PGL   +GP+GP
Sbjct: 896  TGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGL---QGPAGP 952

Query: 904  PGPAGSPGERGAAGSGGPIGP---------------------PGRPGPQGPPGAAGEKGV 942
            PG  G PG+ G +G+ GP GP                     PG PGP G PG  G  G 
Sbjct: 953  PGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA 1012

Query: 943  PGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGP 1002
             G++GP GP G  G+ GP G PG  G PG  G  G  G  G  G +G  G  G  G PGP
Sbjct: 1013 SGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGP 1072

Query: 1003 PGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGE 1062
            PG  GP G  G  G  GE GA+GP G  G  G  G +G  GP G  G  G PG  G KG 
Sbjct: 1073 PGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGH 1132

Query: 1063 TGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGV 1122
             G  G  G PGPPGP G  G +G  GP GP G  G +GP    G+ G +G PG  G PG 
Sbjct: 1133 RGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGP---SGKDGANGIPGPIGPPGP 1189

Query: 1123 KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGA 1182
            +G  GE G  G  G PG PGPPGP GP  D       G    P + GP      R    A
Sbjct: 1190 RGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLG----PREKGPDPLQYMRADQAA 1245

Query: 1183 KGDRGEDGE 1191
             G R  D E
Sbjct: 1246 GGLRQHDAE 1254



 Score =  649 bits (1675), Expect = 0.0
 Identities = 395/879 (44%), Positives = 438/879 (49%), Gaps = 148/879 (16%)

Query: 659  GEDGPEGPKGRTGPTGDPGPPGLMGEKGKL-GVPGLPGYPGRQGPKGSLGFPGFPGASGE 717
            GE  P  P      +G PGP G  GE G +  + G  G PG QGP G  G  G  G  GE
Sbjct: 83   GECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGE 142

Query: 718  KGA---RGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPG---ERGL 771
            KGA   RG  G+ G  G  GP GP G  GP G  G   A+   G D   G       +G 
Sbjct: 143  KGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGP 202

Query: 772  PGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGP 831
             GP GP G PGP G PGP G  G PG PG+ G  G  G  GPPGPPG  G  G AG+ G 
Sbjct: 203  MGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGK 262

Query: 832  MGERGHPGPPGP---PGEQGLPGT---------------AGKEGTKGDPGPPGAPGKDGP 873
             GERG PGP G    PG  GLPG                AG  G KG+ G PG  G  GP
Sbjct: 263  AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGP 322

Query: 874  AGLRGFPGERGLPGTAGGPGLKGNE------GPSGPPGPAGSPGERGAAGSGGPIGPPGR 927
             G RG PGERG  G AG  G +GN+      GP GP GPAG PG  GA G+ G  GP G 
Sbjct: 323  MGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGA 382

Query: 928  PGPQGPPGAAGEKGVPGEKGPIGPTGR---------------DGVQGPVGLPGPAGPPGV 972
             GP+G  G  GE G PG  GP G +G                 G+ G  G PGP GPPG 
Sbjct: 383  RGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGP 442

Query: 973  AGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAA------GADGEPGARGP 1026
             G  G  G  G  G+ G  G KGE GP G PGP GP G PG A      GA GEPG  GP
Sbjct: 443  QGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGP 502

Query: 1027 QGHFGAKGDEGTRGFNGPPGPIGLQGLPGP------SGEKGETGDVGPMGPPGPPGPR-- 1078
             G  G +G  G RGF G  G  G +G PG       +G KG  GD G  G PG PG R  
Sbjct: 503  IGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGL 562

Query: 1079 ----GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGE 1134
                G AGP G  GP G PG  G  GPPG +G  G+   PG+ G PG KG  GE G+ GE
Sbjct: 563  TGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ---PGVMGFPGPKGANGEPGKAGE 619

Query: 1135 SGQPGEP---------------GPPGPKGPTGDDGPKGNPGPVGF---PGDPGPPGEG-- 1174
             G PG P               GPPGP GP G+ G +G PGP GF   PG PGPPGEG  
Sbjct: 620  KGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGK 679

Query: 1175 ----------------GPRGQDGAKGDRGEDGE---------PGQPGSPGPTGENGPPGP 1209
                            GPRG+ G  G+RG  G          PG PG+ GP G +GP GP
Sbjct: 680  PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGP 739

Query: 1210 LGKRGP---AGSPGSEGRQGGKGAKGDPGAI------GAPGK------TGPVGPAGPA-- 1252
             G +GP    G PG  G  G  G KGD G +      GAPGK      TGP+GP GPA  
Sbjct: 740  PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 799

Query: 1253 -------GKPGP---DGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1302
                   G PGP    G RG PG  G+ G PG  G AGPPG  G PG  G +G+AG KG+
Sbjct: 800  NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGD 859

Query: 1303 KGHPGLIGLIGPPGEQ------GEKGDRGLPGPQGS---PGQKGEMGIPGASGPIGPGGP 1353
             G PG  G  G PG Q      G KG RG  GP G+   PG  G +G PG++G  GP GP
Sbjct: 860  AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP 919

Query: 1354 PGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGE 1392
            PG  G  GPKGA+G +GP G  GE G+QGP G PG  GE
Sbjct: 920  PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGE 958



 Score =  421 bits (1082), Expect = e-117
 Identities = 249/548 (45%), Positives = 279/548 (50%), Gaps = 41/548 (7%)

Query: 921  PIGPPGRPGPQGPPGAAGEKGVPGE-KGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDK 979
            PI P       G PG  G+KG PG+ K  +GP G  G QGP G  GP G  G  GE G  
Sbjct: 87   PICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAP 146

Query: 980  GEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARG------PQGHFGAK 1033
            G  G  G+ GT GN G  GPPGPPGP G  G   A  A G     G       QG  G  
Sbjct: 147  GPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM 206

Query: 1034 GDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP---PGPRGPAGPNGADGPQ 1090
            G  G  G  G PGP G QG PG  GE G +G +GP GPPGP   PG  G AG  G  G +
Sbjct: 207  GPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGER 266

Query: 1091 GPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1150
            GPPG  G  G PG  G PG  G  G  G  G KG  G  G KGESG PGE G PGP GP 
Sbjct: 267  GPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPR 326

Query: 1151 GDDGPKGNPGPVGF---------PGDPGPPGEGGPR------GQDGAKGDRGEDGEPGQP 1195
            G  G +G  GP G          PG  GPPG  GP       G  GAKG+ G  G  G  
Sbjct: 327  GLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPE 386

Query: 1196 GSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP 1255
            G+ GP GE G PG  G  G +G+PG++G  G KG+ G PG  GAPG  GP GP GP G  
Sbjct: 387  GAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT 446

Query: 1256 GPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPP 1315
            GP G +G  G  G  G  G  G  G PGP GP G PG  G+ G +G +G PG +G IGPP
Sbjct: 447  GPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPP 506

Query: 1316 GEQGEKGDRGLPGPQGSPGQK---GEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATG-P 1371
            GE+G  G+RG PG  G  G K   GE G  G +GP G  G PG PG  G  GA+G TG P
Sbjct: 507  GERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRP 566

Query: 1372 G--------GPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPT 1423
            G        GP G  G  G PG PGP G   QP  +  P    +  +G      ++ +P 
Sbjct: 567  GDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGP--KGANGEPGKAGEKGLP- 623

Query: 1424 GGAPGSPG 1431
             GAPG  G
Sbjct: 624  -GAPGLRG 630



 Score = 38.1 bits (87), Expect = 0.070
 Identities = 32/96 (33%), Positives = 39/96 (40%), Gaps = 18/96 (18%)

Query: 1348 IGPGGPPGLPGPAGPKGAKGATGPGGPKGEKG-------VQGPPGHPGPPGEVIQPLPIQ 1400
            + P  P G   P  P     A+G  GPKG+KG       + GP G PGP G    P   Q
Sbjct: 76   LSPEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQG----PAGEQ 131

Query: 1401 MPK-----KTRRSVDGSRLMQEDEAIPTGGAPGSPG 1431
             P+     K  +   G R    +   P  G PG PG
Sbjct: 132  GPRGDRGDKGEKGAPGPRGRDGEPGTP--GNPGPPG 165


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score = 1158 bits (2995), Expect = 0.0
 Identities = 657/1428 (46%), Positives = 771/1428 (53%), Gaps = 96/1428 (6%)

Query: 264  QSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGP 323
            Q Q    P G KG+KGEP  ++  +  +GPPGP+GPAG  GP G +G+ G  G PG RG 
Sbjct: 24   QGQDVRQP-GPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGR 82

Query: 324  PGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQA---QAILQQARLALRG 380
             G  G PG+ G PGPPG     P   G GG     +    + +A   Q  + Q  +   G
Sbjct: 83   DGEPGTPGNPGPPGPPGP----PGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMG 138

Query: 381  PPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARG 440
            P GP G  G PGP G  G+PG  GE G  GP GPRGP G   PPGK G  G AG  G  G
Sbjct: 139  PRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPG---PPGKPGDDGEAGKPGKAG 195

Query: 441  MPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESG 500
              G PG +G RGF G PGLPG KGHRG  G  G  G  G  G +G+ G  G  G PG  G
Sbjct: 196  ERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMG 255

Query: 501  PRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIG 560
            PRGL G +G  G  G  G RG DG  GP G  GP G  G PG  G PG +G  GP GA G
Sbjct: 256  PRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARG 315

Query: 561  PHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDG 620
            P G +GP+G+PG PG PG  G  G+PG +G PG KG+ G  G  G  G+PGPRG  G  G
Sbjct: 316  PEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQG 375

Query: 621  IRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPG 680
              G  G KG+ GE G  GFKG+ G KG+ G  G  G+ G  G EG +G  G  G  GP G
Sbjct: 376  ATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIG 435

Query: 681  LMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG---ERGPTG 737
              GE+G  G  G PG  G  GPKG+ G  G  G +G KGA G  G+ G  G    RG TG
Sbjct: 436  PPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTG 495

Query: 738  PRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK---DG 794
              G  GP+G  G SGA G  G  GP GP G RG PG  G   FPGPKG  G PGK    G
Sbjct: 496  RPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMG---FPGPKGANGEPGKAGEKG 552

Query: 795  LPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG---PMGERGHPGPPGPPGEQGLPG 851
            LPG PG RG  G  G+TG  GPPG  GP G  GE G   P G +G PGPPGPPGE     
Sbjct: 553  LPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGE----- 607

Query: 852  TAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG 911
              GK G +G PG  GAPG  GP G RGFPGERG PG  G  G +G  G  G  GP G+ G
Sbjct: 608  -GGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASG 666

Query: 912  ERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPG 971
              G  G+ GP G  G PG +G  G AG KG  G+ G  GP G  G  G  GL GP GPPG
Sbjct: 667  PAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPG 726

Query: 972  VAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFG 1031
             AG +G+KGEVG PG  G+ G +G  G  G  GP GP G  G  GADG+PGA+G QG  G
Sbjct: 727  PAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAG 786

Query: 1032 AKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQG 1091
             KGD G  G  GP G  G QG  G +G KG  G  GP G  G PG  G  GP G++G  G
Sbjct: 787  QKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPG 846

Query: 1092 PPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG---ERGEKGESGQPGEPGPPGPKG 1148
            PPG  G  G  G KG  G+SG PG  GEPG++GP G   E+GE G+ G  G  GPPGP+G
Sbjct: 847  PPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQG 906

Query: 1149 PTGDDGPKGNPGPVG---FPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENG 1205
              G  G  G PG  G   FPG PGP GE G +G  GA GDRG  G  G PG  GP GE  
Sbjct: 907  LAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGE-- 964

Query: 1206 PPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPG 1265
             PG  G  G  G PG +G  G KG +G+ GA+GAPG  GP G  GPAG  G  G RG  G
Sbjct: 965  -PGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAG 1023

Query: 1266 SVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRG 1325
            + G  G  G  G  G  GP GP G  G  G+ G +G KGH G  GL G PG  G  GD+G
Sbjct: 1024 AQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQG 1083

Query: 1326 LPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPG 1385
              GP G  G +G    PG  GP G  G  G+PGP GP G +G +G  GP G  G  GPPG
Sbjct: 1084 ASGPAGPSGPRGP---PGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPG 1140

Query: 1386 HPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLE----EIFGSLD 1441
             PGPPG  I            +  D  + M+ D+A          GGL     E+  +L 
Sbjct: 1141 PPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAA---------GGLRQHDAEVDATLK 1191

Query: 1442 SLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTAG 1501
            SL  +IE +R P G++ +PARTC+DLKLCHPE   G+YW+DPNQGC  DA +VFCN    
Sbjct: 1192 SLNNQIESIRSPEGSRKNPARTCRDLKLCHPEWKSGDYWIDPNQGCTLDAMKVFCNMET- 1250

Query: 1502 GETCVTPR--------------------------DDVTQFSYVDSEGSP-VGVVQLTFLR 1534
            GETCV P                           +    FSY D   +P    VQ+TFLR
Sbjct: 1251 GETCVYPNPANVPKKNWWSSKSKEKKHIWFGETINGGFHFSYGDDNLAPNTANVQMTFLR 1310

Query: 1535 LLSVSAHQDVSYPCSGAAR---------DGPLRLRGANEDELSPETSP--YVKEFRDGCQ 1583
            LLS    Q+++Y C  +              L ++G+N+ E+  E +        +DGC 
Sbjct: 1311 LLSTEGSQNITYHCKNSIAYLDEAAGNLKKALLIQGSNDVEIRAEGNSRFTYTALKDGCT 1370

Query: 1584 T---QQGRTVLEVRTPVLEQLPVLDASFSDLGAPPRRGGVLLGPVCFM 1628
                + G+TV+E R+    +LP++D +  D+G P +  GV +GPVCF+
Sbjct: 1371 KHTGKWGKTVIEYRSQKTSRLPIIDIAPMDIGGPEQEFGVDIGPVCFL 1418



 Score =  816 bits (2109), Expect = 0.0
 Identities = 468/1038 (45%), Positives = 526/1038 (50%), Gaps = 124/1038 (11%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 322
            P    A GP+G +G  GEP   EPG  V GP GP GP G  G PG  G  G  G  GERG
Sbjct: 143  PGPAGAPGPQGFQGNPGEPG--EPG--VSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERG 198

Query: 323  PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAIL-QQARLALRGP 381
            PPG  G  G  G PG PG             G  G   A  EA A  +  +       G 
Sbjct: 199  PPGPQGARGFPGTPGLPGVK--------GHRGYPGLDGAKGEAGAPGVKGESGSPGENGS 250

Query: 382  PGPM------GYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGA 435
            PGPM      G  GR GP G  G+ G  G+ G  GP GP GP G  G PG  G +G AG 
Sbjct: 251  PGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP 310

Query: 436  DGAR---------------GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGE 480
             GAR               G PG  G  G+ G DG+PG  G  G  G  GA G PGP G 
Sbjct: 311  TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP 370

Query: 481  DGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEP-- 538
             G +G  G +GP+G  GE G  G  G +GP G PGP G +G  GP G +G  G +GEP  
Sbjct: 371  PGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGG 430

Query: 539  ----GPPGQQGTPGTQGLP---------------GPQGAIGPHGEKGPQGKPGLPGMPGS 579
                GPPG++G PG +G P               GP G  GP G  G  G+PG PG+PG+
Sbjct: 431  VGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGA 490

Query: 580  DGPPGHPGKEGP---------PGTKGNQGPSGPQGP------LGYPGPRGVKGVDGIRGL 624
             G  G PG  GP         PG  G  GP GPQG       +G+PGP+G  G  G  G 
Sbjct: 491  RGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGE 550

Query: 625  KGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGE 684
            KG  G  G  G PG  G+ G  G  G  G  G RGE G  GP G  G  G PGPPG  G+
Sbjct: 551  KGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGK 610

Query: 685  KGKLGVPGLPGYPGRQGPKGSLGFP---GFPGASGEKGARGL---SGKSGPRGERGPTGP 738
             G  GVPG  G PG  GP+G  GFP   G PGA G +G RGL    G  GP+G  GP GP
Sbjct: 611  PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGP 670

Query: 739  RGQRGPRGATGKSGAKGTSG-----GD-------GPHGPPGE---RGL------PGPQGP 777
             G +GP G  G  G +G +G     GD       GP G PG+   RGL      PGP G 
Sbjct: 671  PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 730

Query: 778  NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 837
            NG  G  GPPGP G  G  G PG+RGE G  G  G  GPPG  G  GA GE G  G++G 
Sbjct: 731  NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGD 790

Query: 838  PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 897
             G PGP G  G P   G +G  G  GP GA G  GP G  GFP   G  G  G PG  GN
Sbjct: 791  AGAPGPQGPSGAP---GPQGPTGVTGPKGARGAQGPPGATGFP---GAAGRVGPPGSNGN 844

Query: 898  EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGE------KGPIGP 951
             GP GPPGP+G  G +GA G  GP G  G PG QGP G  GEKG PG+      +GP GP
Sbjct: 845  PGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGP 904

Query: 952  TGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQ 1011
             G  G +G VGLPG  G  G  G  G  GE G  G  G  G++G  GP GPPG  GP G+
Sbjct: 905  QGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGE 964

Query: 1012 PGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGP 1071
            PG  G+ G  G  G  G  G KGD G  G  G PG  G  G PGP+G  G+ GD G  G 
Sbjct: 965  PGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGA 1024

Query: 1072 PGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGE 1131
             GP GP GPAG  G  GPQGP G  G  G PGE+G  G  G  G+QG PG  GP G++G 
Sbjct: 1025 QGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGA 1084

Query: 1132 KGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGE 1191
             G +G  G  GPPGP GP+G DG  G PGP+G P         GPRG+       GE G 
Sbjct: 1085 SGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPP---------GPRGRS------GETGP 1129

Query: 1192 PGQPGSPGPTGENGPPGP 1209
             G PG+PGP G  GPPGP
Sbjct: 1130 AGPPGNPGPPGPPGPPGP 1147



 Score =  743 bits (1919), Expect = 0.0
 Identities = 441/1029 (42%), Positives = 503/1029 (48%), Gaps = 102/1029 (9%)

Query: 229  EGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGM 288
            + G+R  P  Q       +P     + HR       ++   G  G+KGE G P       
Sbjct: 193  KAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPG------ 246

Query: 289  LVEGPPGPEGPAGL------IGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTS 342
               G PGP GP GL       GP G  G  G  G PG  GPPG  G  G  G PG PG  
Sbjct: 247  -ENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAK 305

Query: 343  LMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQP----- 397
                       G+ GP  A     AQ    +      G PGP G +G PG  G P     
Sbjct: 306  -----------GEAGPTGARGPEGAQG--PRGEPGTPGSPGPAGASGNPGTDGIPGAKGS 352

Query: 398  -GSPGLKGESGDLGPQGPRGPQGLT---GPPGKAGRRGRAGADGARGMPGDPGVKGDRGF 453
             G+PG+ G  G  GP+GP GPQG T   GP G+ G  G AG  G +G  G+PG  G +G 
Sbjct: 353  AGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGA 412

Query: 454  DGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGD------DGEIGPRGLPGESGPRGLLGP 507
             G  G  G++G RG+ G  G  GPPGE G  G+      DG  GP+G PGE GP GL GP
Sbjct: 413  PGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGP 472

Query: 508  KGP------PGIPGPPGVRGMD------GPQ---GPKGSLGPQGEPGPPGQQGT---PGT 549
            KG       PG PG PG RG+       GPQ   GP G+ G  G PGPPG QG    PG 
Sbjct: 473  KGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGV 532

Query: 550  QGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGY 609
             G PGP+GA   +GE G  G+ GLPG PG  G PG  G+ G  G  G  GP+G +G  G 
Sbjct: 533  MGFPGPKGA---NGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 589

Query: 610  PGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGR 669
            PGP G +G+ G  G  G  G+ G+ G PG  G  G+ G RGE G PG RG  G +G +G 
Sbjct: 590  PGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGP 649

Query: 670  TGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGAS------GEKGARGL 723
             G  G PG  G  G  G  G PG  G PG QG  G  G  G  G        GEKG  G 
Sbjct: 650  RGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGA 709

Query: 724  SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 783
             GK G RG  GP GP G  G  G  G+ G  G +G  G  G PGERG  GP GP GF GP
Sbjct: 710  PGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGP 769

Query: 784  KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 843
             G  G PG  G  G  GQ+G+    G  GP GP G  GPQG  G TGP G RG  GPPG 
Sbjct: 770  PGADGQPGAKGEQGEAGQKGDA---GAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGA 826

Query: 844  PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 903
             G  G  G  G  G+ G+PGPPG PG  G  G +G  G+ G PG AG PGL   +GP+GP
Sbjct: 827  TGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGL---QGPAGP 883

Query: 904  PGPAGSPGERGAAGSGGPIGP---------------------PGRPGPQGPPGAAGEKGV 942
            PG  G PG+ G +G+ GP GP                     PG PGP G PG  G  G 
Sbjct: 884  PGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA 943

Query: 943  PGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGP 1002
             G++GP GP G  G+ GP G PG  G PG  G  G  G  G  G +G  G  G  G PGP
Sbjct: 944  SGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGP 1003

Query: 1003 PGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGE 1062
            PG  GP G  G  G  GE GA+GP G  G  G  G +G  GP G  G  G PG  G KG 
Sbjct: 1004 PGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGH 1063

Query: 1063 TGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGV 1122
             G  G  G PGPPGP G  G +G  GP GP G  G +GP    G+ G +G PG  G PG 
Sbjct: 1064 RGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGP---SGKDGANGIPGPIGPPGP 1120

Query: 1123 KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGA 1182
            +G  GE G  G  G PG PGPPGP GP  D       G    P + GP      R    A
Sbjct: 1121 RGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLG----PREKGPDPLQYMRADQAA 1176

Query: 1183 KGDRGEDGE 1191
             G R  D E
Sbjct: 1177 GGLRQHDAE 1185


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 1138 bits (2943), Expect = 0.0
 Identities = 646/1412 (45%), Positives = 756/1412 (53%), Gaps = 134/1412 (9%)

Query: 295  GPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGG 354
            G EGP G  GP   +G  GP G PG  G PG+ GLPG  G PGPPG         G GG 
Sbjct: 109  GVEGPKGDTGP---RGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPP-------GLGGN 158

Query: 355  DKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKG---ESGDLGP 411
                  A Q +          +++ GP GP G  G PGP G PG  G +G   E G+ G 
Sbjct: 159  -----FAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGA 213

Query: 412  QGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGA 471
             GP GP+G  GPPGK G  G AG  G  G  G PG +G RG  G  GLPG KGHRG +G 
Sbjct: 214  SGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGL 273

Query: 472  QGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGS 531
             G  G  G  G +G+ G  G  G PG+ GPRGL G +G PG PGP G RG DG  G  G 
Sbjct: 274  DGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGP 333

Query: 532  LGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGP 591
             GP G  GPPG  G  G +G  GPQG  G  G +G +G+PG PG  G+ GP G+PG +G 
Sbjct: 334  PGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQ 393

Query: 592  PGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGE 651
            PG KG  G  G  G  G+PG RG  G  G  G  G KG  GE G PG KGD G KG+ G 
Sbjct: 394  PGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGP 453

Query: 652  VGV---PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGF 708
            VGV   PG  GE+G  G +G  GPTG PGPPG  G  G  G PG  G  G +GP G  G 
Sbjct: 454  VGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGS 513

Query: 709  PGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE 768
            PG  G  G  G  G  G++G  G +G TG  G  GP G TG  G  G  G  GP GPPG 
Sbjct: 514  PGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGA 573

Query: 769  RGLPGPQGPNGFPGPKGPPGPPGKDG---LPGHPGQRGEVGFQGKTGPPGPPGVVGPQGA 825
            RG  G  G   FPGPKG  G PGK G   +PG PG  G  G  G+ G  GPPG  GP G 
Sbjct: 574  RGQAGVMG---FPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGE 630

Query: 826  AGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGL 885
             GE GP G  G  G PGP G    PG AGK G +G PG  GAPG  G  G RGFPGERG+
Sbjct: 631  RGEQGPAGSPGFQGLPGPAGP---PGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGV 687

Query: 886  ---PGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGV 942
               PG AG  G  G  G  G  G AG+PG  G+ G+ G  G PG  G  G PG  G++G 
Sbjct: 688  QGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGD 747

Query: 943  PGEKGPIGPTGRDGVQG---PVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 999
             G KG  G  G+DGV+G   P+G PGPAG PG  GE G  G  G  G +G  G++GE   
Sbjct: 748  AGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGE--- 804

Query: 1000 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1059
            PGPPGP G  G P   GADG+PGA+G  G  GAKGD       GPPGP G  G PGP   
Sbjct: 805  PGPPGPAGFAGPP---GADGQPGAKGEPGDAGAKGDA------GPPGPAGPAGPPGP--- 852

Query: 1060 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1119
                  +G +G PG  G RG AGP GA    G PG  G +GPPG  G  G  G PG  G+
Sbjct: 853  ------IGNVGAPGAKGARGSAGPPGA---TGFPGAAGRVGPPGPSGNAGPPGPPGPAGK 903

Query: 1120 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQ 1179
             G KGPRG   E G +G+PGE GPPGP GP G+ G  G  GP G PG PGP G  G RG 
Sbjct: 904  EGGKGPRG---ETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGV 960

Query: 1180 DGAKGDRGE---------DGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGA 1230
             G  G RGE          GEPG+ G  G +GE GPPGP+G  G AG PG  GR+G  GA
Sbjct: 961  VGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGA 1020

Query: 1231 KGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGL 1290
            +G PG  G+PG  G  G  GPAG PG  G  G PG VG  G+ G  G+ GP GP GP G 
Sbjct: 1021 EGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGP 1080

Query: 1291 PGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGP 1350
             G RG AG +G +G  G  G  G  G +G +G  GL GP G PG  GE G  GASGP GP
Sbjct: 1081 VGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGP 1140

Query: 1351 GGPP------------GLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1398
             GPP            GLPGP GP G +G TG  GP G  G  GPPG PGPP        
Sbjct: 1141 RGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSF 1200

Query: 1399 IQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQD 1458
            +  P +  ++ DG R  + D+A              E+  +L SL ++IE +R P G++ 
Sbjct: 1201 LPQPPQ-EKAHDGGRYYRADDANVVRDRD------LEVDTTLKSLSQQIENIRSPEGSRK 1253

Query: 1459 SPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGETCVTPRD-------- 1510
            +PARTC+DLK+CH +   GEYW+DPNQGC  DA +VFCN    GETCV P          
Sbjct: 1254 NPARTCRDLKMCHSDWKSGEYWIDPNQGCNLDAIKVFCNMET-GETCVYPTQPSVAQKNW 1312

Query: 1511 -------------------DVTQFSYVDSEGSPVGV-VQLTFLRLLSVSAHQDVSYPCSG 1550
                               D  QF Y      P  V +QLTFLRL+S  A Q+++Y C  
Sbjct: 1313 YISKNPKDKRHVWFGESMTDGFQFEYGGQGSDPADVAIQLTFLRLMSTEASQNITYHCKN 1372

Query: 1551 AA-----RDGPLR----LRGANEDELSPE-TSPYVKEFR-DGCQTQQ---GRTVLEVRTP 1596
            +      + G L+    L+G+NE E+  E  S +      DGC +     G+TV+E +T 
Sbjct: 1373 SVAYMDQQTGNLKKALLLQGSNEIEIRAEGNSRFTYSVTVDGCTSHTGAWGKTVIEYKTT 1432

Query: 1597 VLEQLPVLDASFSDLGAPPRRGGVLLGPVCFM 1628
               +LP++D +  D+GAP +  G  +GPVCF+
Sbjct: 1433 KTSRLPIIDVAPLDVGAPDQEFGFDVGPVCFL 1464



 Score =  736 bits (1900), Expect = 0.0
 Identities = 422/906 (46%), Positives = 465/906 (51%), Gaps = 96/906 (10%)

Query: 577  PGSDGPPGH-----PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEK 631
            PG++ P G      P     P  +   G  GP+G  G  GPRG  G  G  G+ G  G  
Sbjct: 82   PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLP 141

Query: 632  GEDGFPGFKGDIGVKGDRGEVGVPG----SRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 687
            G  G PG  G  G+ G+       G    S G     GP G +GP G PGPPG  G +G 
Sbjct: 142  GPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGF 201

Query: 688  LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPR-------- 739
             G PG PG PG  GP G  G PG PG +G+ G  G  G+ G RG  GP G R        
Sbjct: 202  QGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGL 261

Query: 740  -GQRGPRGATGKSGAKGTSGGDGPH---GPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL 795
             G +G RG +G  GAKG +G  GP    G PGE G PG  GP G PG +G PG PG  G 
Sbjct: 262  PGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGA 321

Query: 796  PGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGK 855
             G+ G  G  G  G TGP GPPG  G  GA GE GP G RG  GP G  GE G PG AG 
Sbjct: 322  RGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGA 381

Query: 856  EGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGA 915
             G  G+PG  G P   G  G  G PG  G PG  G  G  G +GP GPPGP G+ GE GA
Sbjct: 382  AGPAGNPGADGQP---GAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGA 438

Query: 916  AGSGGPIGPPGRPGP---QGPPGAAGEKGVPGEKGPIGPT------------------GR 954
             GS G  G  G PGP   QGPPG AGE+G  G +G  GPT                  G 
Sbjct: 439  PGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGA 498

Query: 955  DGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1014
            DGV GP G  G  G PG AG  G  GE G PG+ G  G KG  G PG PGP G  G PG 
Sbjct: 499  DGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGP 558

Query: 1015 AGADGEPGARGPQGHFGAKGDEGTRGFNGP------PGPIGLQGLPGPSGEKGETGDVGP 1068
            AG DG PG  GP    GA+G  G  GF GP      PG  G +G+PGP G  G  G  G 
Sbjct: 559  AGQDGRPGPPGPP---GARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGE 615

Query: 1069 MGPPGPPGPRGPAGPNGADGPQGPPG--GV-GNLGPPGEKGEPGESGSPGIQGEPGVKGP 1125
             G  GPPGP GPAG  G  GP G PG  G+ G  GPPGE G+PGE G PG  G PG  G 
Sbjct: 616  AGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGA 675

Query: 1126 RGERGEKGESGQPGEPGPPGPKGPT---GDDGPKGN------PGPVGFPGDPGPPGEGGP 1176
            RGERG  GE G  G PGP GP+G     G+DG KG+      PG  G PG  G PGE G 
Sbjct: 676  RGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGA 735

Query: 1177 RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGA 1236
             G  G KGDRG+ G  G  GSPG  G  G  GP+G  GPAG+PG +G  G  G  G  GA
Sbjct: 736  AGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGA 795

Query: 1237 IGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGP--------- 1287
             GAPG  G  GP GPAG  GP G  G PG+ G+ G  GA G AGPPGP GP         
Sbjct: 796  RGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGN 855

Query: 1288 ---PGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGA 1344
               PG  G RG AG  G  G PG  G +GPPG  G  G  G PGP G  G KG  G  G 
Sbjct: 856  VGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGP 915

Query: 1345 SGPIGPGGPPGLPGPAGPKGAKGATGPGGP------------------KGEKGVQGPPGH 1386
            +G  G  GPPG PGPAG KG+ GA GP G                    G++G +G PG 
Sbjct: 916  AGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGL 975

Query: 1387 PGPPGE 1392
            PGP GE
Sbjct: 976  PGPSGE 981



 Score =  597 bits (1539), Expect = e-170
 Identities = 360/826 (43%), Positives = 412/826 (49%), Gaps = 110/826 (13%)

Query: 262  EPQSQAAHGPRGLKGEKGEPAVLEPG--MLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPG 319
            +P ++ A+G  G+ G  G P    P       GPPGP+G +G  G PG +G+ G  G+PG
Sbjct: 393  QPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPG 452

Query: 320  E---RGPPGRAGLPGSDGAPGPPG-TSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQAR 375
                +GPPG AG  G  GA G PG T L  P     G G +G   A   A  +    +  
Sbjct: 453  PVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGE-- 510

Query: 376  LALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGA 435
               RG PGP G  G PG  G+PG  GL G  G  G  G  GP G TGPPG AG+ GR G 
Sbjct: 511  ---RGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGP 567

Query: 436  DGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGL 495
                  PG PG +G  G  G PG  G  G  G  G +G+PGPPG  G  G DGE G +G 
Sbjct: 568  ------PGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGP 621

Query: 496  PGESGP---------------RGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP 540
            PG +GP               +GL GP GPPG  G PG +G+ G  G  G  G +GE G 
Sbjct: 622  PGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGF 681

Query: 541  PGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGP 600
            PG++G  G  G  GP+GA G  G  G +G  G PG PGS G PG  G  G  G  G  GP
Sbjct: 682  PGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGP 741

Query: 601  SGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV---PGS 657
             G +G  G  G  G  G DG+RGL G  G  G  G PG KG+ G  G  G  G    PG 
Sbjct: 742  KGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGD 801

Query: 658  RGEDGPEGPKGRTGPTGDPGPPGLMGE------KGKLGVPGLPGYPGRQGPKGSLGFPG- 710
            RGE GP GP G  GP G  G PG  GE      KG  G PG  G  G  GP G++G PG 
Sbjct: 802  RGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGA 861

Query: 711  --------------FPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGT 756
                          FPGA+G  G  G SG +GP G  GP G  G +GPRG TG +G  G 
Sbjct: 862  KGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGE 921

Query: 757  SGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP 816
             G  GP GP GE+G PG  GP G PG  GP G  G+ G+ G PGQRGE GF G  GP G 
Sbjct: 922  VGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGE 981

Query: 817  PGVVGPQGAAGETGPMGERGHPGPPGPPGE---------QGLPGTAGKEGTKGD------ 861
            PG  GP GA+GE GP G  G PG  GPPGE         +G PG  G  G KGD      
Sbjct: 982  PGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGP 1041

Query: 862  ---PGPPGAPGKDGPAGLRGFPGERGLPGTAG-----------------GP--------- 892
               PG PGAPG  GP G  G  G+RG  G AG                 GP         
Sbjct: 1042 AGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGE 1101

Query: 893  ----GLKGNEGPSG---PPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGE 945
                G+KG+ G SG   PPGP GSPGE+G +G+ GP GP G PG  G PG  G  G+PG 
Sbjct: 1102 QGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGP 1161

Query: 946  KGPIGPTGRDGVQGPVGLPG---PAGPPGVAGEDGDKGEVGDPGQK 988
             GP GP GR G  GPVG PG   P GPPG      D   +  P Q+
Sbjct: 1162 IGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQE 1207


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 1124 bits (2906), Expect = 0.0
 Identities = 645/1449 (44%), Positives = 768/1449 (53%), Gaps = 126/1449 (8%)

Query: 260  NQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPG 319
            +Q P     +  RG KG+KGEP ++     + G PGP GP G  GP   +G  GP G PG
Sbjct: 97   SQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGP---RGERGPKGRPG 153

Query: 320  ERGPPG---RAGLPGSDGAPGPPG-------TSLMLPFRFGSGGGDKGPVVAAQEAQAQA 369
             RGP G     G+PG  GAPGPPG         L  PF     G D+   + +Q      
Sbjct: 154  PRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVG---- 209

Query: 370  ILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGR 429
             L    +   GP GP G  G+ G  G  G PG  G+ G +GP G RGP+G  G PG+ G 
Sbjct: 210  -LMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGE 268

Query: 430  RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGE 489
             GR G  G  G  G PG +G  G  GLPGL G +GH+G  G +G  G PG  GE G  G 
Sbjct: 269  PGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGP 328

Query: 490  ------IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQ 543
                  +GPRG+PGE   RG LGP+G PG  G  G+ G  GP GP G  G  G PG PG 
Sbjct: 329  MGAMGPLGPRGMPGE---RGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGM 385

Query: 544  QGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGP 603
            +G  G  G  GP+G  G  GE GP G  G PG+PG+ G  G PG +GP G+ G  GP G 
Sbjct: 386  KGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGS 445

Query: 604  QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGP 663
             GP G PGP+G  G  GIRG      + G+ G PGFKG+ G KG+ G  G+   +G  GP
Sbjct: 446  AGPPGSPGPQGSTGPQGIRG------QPGDPGVPGFKGEAGPKGEPGPHGI---QGPIGP 496

Query: 664  EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 723
             G +G+ GP GDPG  G  G  G+ G PG  G+PG      S G PG  GA GE+G  G 
Sbjct: 497  PGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPG------SDGLPGPKGAQGERGPVGS 550

Query: 724  SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGF--- 780
            SG  G +G+ G  G  G  G RG TG  G +G  G  GP G PGE G PGP G  G    
Sbjct: 551  SGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQ 610

Query: 781  PGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGP 840
            PG  G PGP G  G PG PG+ G  G  G+ G PG  G VGP G  G  G  GERG  GP
Sbjct: 611  PGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGP 670

Query: 841  PGPPGEQGLPGT------AGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGL 894
            PGP G QGLPG        GK G +G PG PGA G  GP G RG PGERG PG  G PG 
Sbjct: 671  PGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGE 730

Query: 895  KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQG---PPGAAGEKGVPGEKGPIGP 951
            KG  G  GP GP GSPG  G  G  GP G  G PG +G    PG  G++G  GEKG  G 
Sbjct: 731  KGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGT 790

Query: 952  TGRDGVQG---PVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGP---PGP 1005
             G DG +G   P+G PGPAGP G  GE G +G VG PG +G  G++GE+GP G     GP
Sbjct: 791  AGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGP 850

Query: 1006 IGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGD 1065
             GP GQPG  G  GEPG +G  G        G +G  G PGP G  G+PG  G +G  G 
Sbjct: 851  QGPDGQPGVKGEPGEPGQKGDAG------SPGPQGLAGSPGPHGPNGVPGLKGGRGTQGP 904

Query: 1066 VGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGP 1125
             G  G PG  G  GP GP GA GP GP G  G  GPPG +G+PG  G  G +G  G  G 
Sbjct: 905  PGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGG 964

Query: 1126 RGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP---GPVGFPGDPGPPGEGGPRGQDGA 1182
             G++G+ GE GQPG  GPPGP G TG  G  G P   G  G PG PGP G  G  G  GA
Sbjct: 965  PGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGA 1024

Query: 1183 KGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGK 1242
             GD+G  G  G PGS GP GE GP GP G     G+PG +G  G +G +GDPG  G PG 
Sbjct: 1025 TGDKGPPGPVGPPGSNGPVGEPGPEGPAGN---DGTPGRDGAVGERGDRGDPGPAGLPGS 1081

Query: 1243 TGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1302
             G  G  GP G PG  G RG PGS G  G PG  G+ G PGP GP G  G  GD G +G+
Sbjct: 1082 QGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQ 1141

Query: 1303 KGH---PGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGP 1359
            KGH    GL GL GPPG  GE+G  G+PGP G  G       PG  GP G  G PG  GP
Sbjct: 1142 KGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGP------PGPVGPSGKEGNPGPLGP 1195

Query: 1360 AGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDE 1419
             GP G +G+ G  GP+G  G  GPPG PGPPG +   L   M        D      ED+
Sbjct: 1196 IGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQ 1255

Query: 1420 AIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEY 1479
            A P       PG    +  +L SL  +IE MR P G++  PARTC DLKLCH     GEY
Sbjct: 1256 AAPDDKNKTDPG----VHATLKSLSSQIETMRSPDGSKKHPARTCDDLKLCHSAKQSGEY 1311

Query: 1480 WVDPNQGCARDAFRVFCNFTAGGETCVT------PR--------------------DDVT 1513
            W+DPNQG   DA +V+CN    GETC++      PR                    +  +
Sbjct: 1312 WIDPNQGSVEDAIKVYCNMET-GETCISANPSSVPRKTWWASKSPDNKPVWYGLDMNRGS 1370

Query: 1514 QFSYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPCSGAA--RDGPLR-------LRGANE 1564
            QF+Y D +     + Q+TFLRLLS  A Q+++Y C  +    D   +       L+GAN+
Sbjct: 1371 QFAYGDHQSPNTAITQMTFLRLLSKEASQNITYICKNSVGYMDDQAKNLKKAVVLKGAND 1430

Query: 1565 DELSPETSPYVK--EFRDGCQTQQ---GRTVLEVRTPVLEQLPVLDASFSDLGAPPRRGG 1619
             ++  E +   +    +D C  +    G+TV E RT  + +LP++D +  D+G   +  G
Sbjct: 1431 LDIKAEGNIRFRYIVLQDTCSKRNGNVGKTVFEYRTQNVARLPIIDLAPVDVGGTDQEFG 1490

Query: 1620 VLLGPVCFM 1628
            V +GPVCF+
Sbjct: 1491 VEIGPVCFV 1499



 Score =  747 bits (1928), Expect = 0.0
 Identities = 446/1016 (43%), Positives = 500/1016 (49%), Gaps = 138/1016 (13%)

Query: 540  PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQG 599
            PPG+   P     PG        G KG +G+PGL  +P   G  G PG  GPP   G+QG
Sbjct: 88   PPGEC-CPVCSQTPGGGNTNFGRGRKGQKGEPGL--VPVVTGIRGRPGPAGPP---GSQG 141

Query: 600  PSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPG--------------------- 638
            P G +GP G PGPRG +G+DG  G+ G  G  G  G P                      
Sbjct: 142  PRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEK 201

Query: 639  ---------FKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLG 689
                       G +G  G RG  G+ G +G  GP GP G  G  G  GP G  G +G  G
Sbjct: 202  SGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPG 261

Query: 690  VPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATG 749
             PG  G PGR G  G +GF G PGA G  GA GL G  G RG +G  GP+G+ G  G+ G
Sbjct: 262  KPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKG 321

Query: 750  KSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQG 809
            ++G  G  G  GP GP   RG+PG +G     GP+G PG  G  G+PG PG  G +G  G
Sbjct: 322  EAGPTGPMGAMGPLGP---RGMPGERGR---LGPQGAPGQRGAHGMPGKPGPMGPLGIPG 375

Query: 810  KTGPPGPPGV---VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPG 866
             +G PG PG+    GP GA G  GP G+RG  GPPGP G  GLPG  G +GT G  GP G
Sbjct: 376  SSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTG 435

Query: 867  APGKDGPAGLRGFPGE------------RGLPGTAGGPGLKGNEGPSGPPGPAGSPGERG 914
            +PG  GP G  G PG             RG PG  G PG KG  GP G PGP G  G  G
Sbjct: 436  SPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIG 495

Query: 915  AAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAG 974
              G  G  GP G PG  GPPG  GE+G PG +G  G  G  G +G  G  GP G  G  G
Sbjct: 496  PPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKG 555

Query: 975  EDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGA---RGPQGHFG 1031
              GD G  G+PG  G +G  G  G  GP G +GP+G PG  G  G PG+   RG  G  G
Sbjct: 556  SQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMG 615

Query: 1032 AKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQG 1091
              G +G+ G  G PG  G  G+PG  G  G+ G+VGP GP GPPG  G  G  G  GP G
Sbjct: 616  LPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTG 675

Query: 1092 PPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT- 1150
              G  G  GPPGE G+PG+ G PG  G  G  GPRGERG  GE G+PG  G PG KG   
Sbjct: 676  FQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAG 735

Query: 1151 --GDDGPKGNPGPVGFPGDPGP------PGEGGPRGQDGAKGDRGEDGEP---------- 1192
              G DGPKG+PGP G PGD GP      PGE G  G  G KGDRG  GE           
Sbjct: 736  GHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDG 795

Query: 1193 --------GQPGSPGPTGENGPPGPLGKRGPAGS---PGSEGRQGGKGA----------- 1230
                    G PG  GPTGE G PGP G  GP GS   PGS G  G  GA           
Sbjct: 796  ARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDG 855

Query: 1231 ----KGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLP---GSVGQQGRPGATGQAGPPG 1283
                KG+PG  G  G  G  GP G AG PGP G  G+P   G  G QG PGATG  G  G
Sbjct: 856  QPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAG 915

Query: 1284 PVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPG 1343
             VGPPG  G  G AG  GE G  G  GL G PG  G  GDRG  GP G PG KG+ G  G
Sbjct: 916  RVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDG 975

Query: 1344 ASGPIGPGGP---------------------PGLPGPAGPKGAKGATGPGGPKGEKGVQG 1382
              GP GP GP                     PGLPGPAG  G  G TG  G KG  G  G
Sbjct: 976  QPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVG 1035

Query: 1383 PPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP-------TGGAPGSPG 1431
            PPG  GP GE     P        R  DG+   + D   P       + GAPG+PG
Sbjct: 1036 PPGSNGPVGEPGPEGPAGNDGTPGR--DGAVGERGDRGDPGPAGLPGSQGAPGTPG 1089


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 1104 bits (2855), Expect = 0.0
 Identities = 638/1414 (45%), Positives = 744/1414 (52%), Gaps = 117/1414 (8%)

Query: 293  PPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSG 352
            P  P  P    GP G +G+PGP G PG  G PG  G PGS G+PGPPG     P    +G
Sbjct: 92   PTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCP----TG 147

Query: 353  GGDKGPVVAAQEAQAQAIL-----QQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESG 407
              +  P   + + ++   +             GPPGP G +G PG  G PG  G  GE G
Sbjct: 148  PQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPG 207

Query: 408  DLGPQGPRGPQGLTGPPGKAGR---RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKG 464
              GP GP GP G  GP G AG+    GR G  G RG+PG PG+KG  G   +PG PG KG
Sbjct: 208  QAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAG---IPGFPGMKG 264

Query: 465  HRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDG 524
            HRG  G  G  G  G  G +G++G  G  G PG  GPRG  G +G PG+PG  G RG DG
Sbjct: 265  HRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDG 324

Query: 525  PQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPG 584
             +G  G  GP G PG  G  G+PG +G  GP G+ G +G  G +G+PG  G  G+ GPPG
Sbjct: 325  ARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPG 384

Query: 585  HPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIG 644
             PG  G PG KG  GP+G  G  G  G RG  G  G  G  G +G  GE G  G KG+ G
Sbjct: 385  PPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPG 444

Query: 645  VKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKG 704
             +G+RGE G+PG  G  G +G  G  G  G  G PG  GE+G          PG +GP G
Sbjct: 445  PRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGA---------PGFRGPAG 495

Query: 705  SLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHG 764
              G PG  G +GE+GA G +G  G  GE G  G  G  G RG  G  G  G+ G  GP G
Sbjct: 496  PNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPG 555

Query: 765  PPGERGLPGPQGPNG---FPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVG 821
              GE G PGP GP+G    PG  G PGP G DG PG  G+RG  G  G  GPPG  G  G
Sbjct: 556  SQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETG 615

Query: 822  PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPG------APGKDGPAG 875
            PQG  G TGP G++G  GPPGP G QGLPGT G  G  G PG PG      APG  G  G
Sbjct: 616  PQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKG 675

Query: 876  LRGFPGERGLPGTAGGPGLKGNEGPSGPPG---PAGSPGERGAAGSGGPIGPPGRPGPQG 932
              G PGERG PG AG PGL+G  GP GP G    AG PG  GAAG+ G  G PG  G  G
Sbjct: 676  DAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLG 735

Query: 933  PPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKG 992
             PG  G+KG PG  G  G  G+DG +GP G   P GPPG AG+ GDKGE G PG  G  G
Sbjct: 736  SPGPKGDKGEPGGPGADGVPGKDGPRGPTG---PIGPPGPAGQPGDKGEGGAPGLPGIAG 792

Query: 993  NKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQG 1052
             +G  G  G  GP GP G PGA G +GEPG +G +G  G KG+ G  G  GPPG  G  G
Sbjct: 793  PRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAG 852

Query: 1053 LPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESG 1112
             PGP G KGE G  G  G  G PG RG  GP G++G  GPPG  G+   PG+ G PG +G
Sbjct: 853  PPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGS---PGKDGPPGPAG 909

Query: 1113 SPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG 1172
            + G  G PGV GP+G+ G+ GE G PG  GPPG  GP G  G  G  G  G PG PGP G
Sbjct: 910  NTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRG 969

Query: 1173 EGGPRG------QDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQG 1226
              GP+G      + GA G  GE G PG  G PG  G  G PG  G  G  G PG +G  G
Sbjct: 970  SPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPG 1029

Query: 1227 GKGAKGD---PGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPG 1283
            GKG +G+   PGA GAPG  GP GP GPAGK G    RG  G  G  G PG  G  G PG
Sbjct: 1030 GKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGD---RGESGPAGPAGAPGPAGSRGAPG 1086

Query: 1284 PVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPG 1343
            P GP G  G  G+ GA G KGH G  G  G PG          PGP G  G  G  G  G
Sbjct: 1087 PQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGS---------PGPAGQQGAIGSPGPAG 1137

Query: 1344 ASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPK 1403
              GP+GP GPPG  G +G  G  G  GP G +GE+G +G PGHPG PG    P P   P 
Sbjct: 1138 PRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPG---PPGPPGAPG 1194

Query: 1404 KTRRSVDGSRLMQEDEAIPTGGAP-------GSPGGLEEIFGSLDSLREEIEQMRRPTGT 1456
                 V  + +         G AP             +EI  SL S+  +IE +  P G+
Sbjct: 1195 PCCGGVGAAAIAGIGGEKAGGFAPYYGDEPMDFKINTDEIMTSLKSVNGQIESLISPDGS 1254

Query: 1457 QDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGETCVT------PR- 1509
            + +PAR C+DLK CHPEL  GEYWVDPNQGC  DA +VFCN    GETC++      PR 
Sbjct: 1255 RKNPARNCRDLKFCHPELKSGEYWVDPNQGCKLDAIKVFCNMET-GETCISANPLNVPRK 1313

Query: 1510 -------------------DDVTQFSYVDSE-GSPVGVVQLTFLRLLSVSAHQDVSYPC- 1548
                               D   QFSY + E    V  VQL FLRLLS  A Q+++Y C 
Sbjct: 1314 HWWTDSSAEKKHVWFGESMDGGFQFSYGNPELPEDVLDVQLAFLRLLSSRASQNITYHCK 1373

Query: 1549 ---------SGAARDGPLRLRGANEDELSPETSP--YVKEFRDGCQTQQG---RTVLEVR 1594
                     SG  +   L+L G+NE E   E +         DGC    G   +TV E R
Sbjct: 1374 NSIAYMDQASGNVKKA-LKLMGSNEGEFKAEGNSKFTYTVLEDGCTKHTGEWSKTVFEYR 1432

Query: 1595 TPVLEQLPVLDASFSDLGAPPRRGGVLLGPVCFM 1628
            T    +LP++D +  D+G P +  GV +GPVCF+
Sbjct: 1433 TRKAVRLPIVDIAPYDIGGPDQEFGVDVGPVCFL 1466



 Score =  879 bits (2270), Expect = 0.0
 Identities = 515/1176 (43%), Positives = 584/1176 (49%), Gaps = 123/1176 (10%)

Query: 221  CEQKELECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAH-GPRGLKGEKG 279
            C+ +EL+C       P+          PQ   +    P  Q PQ      GP G+ G  G
Sbjct: 67   CDDQELDCPN-----PEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNG 121

Query: 280  EPAV----------------------------------LEPGMLV---EGPPGPEGPAGL 302
            +P +                                  ++ G+ V    G PGP GP G 
Sbjct: 122  DPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGP 181

Query: 303  IGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAA 362
             GPPG  G+PG  G PG +GPPG  G  G  G PGPPG             G  GP  A 
Sbjct: 182  PGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAI-----------GPSGP--AG 228

Query: 363  QEAQAQAILQQARLALRGPP---------------GPMGYTGRPGPLGQPGSPGLKGES- 406
            ++ ++    +     L GPP               G  G+ GR G  G+ G+PGLKGE+ 
Sbjct: 229  KDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENG 288

Query: 407  --------GDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPG 458
                    G +GP+G  G +G  G PG AG RG  GA G+ G PG PG  G  GF G PG
Sbjct: 289  LPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPG 348

Query: 459  LPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPG 518
              GE G  G  G+ G PG  GE G +G  G  GP G PG +G  G  G  GP GIPG PG
Sbjct: 349  AKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPG 408

Query: 519  VRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 578
            + G  GP GP G+ G  G  G  G+ G  G +G PGP+   G  GE G  G PG  G  G
Sbjct: 409  LMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPR---GERGEAGIPGVPGAKGEDG 465

Query: 579  SDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPG 638
             DG PG PG  G PG  G +G  G +GP G  G  G KG  G RG  G  G +G  G PG
Sbjct: 466  KDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPG 525

Query: 639  FKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPG 698
              G  G  G RG  G PG  G DG  GP G  G +G PGPPG  G +G+ GV G PG  G
Sbjct: 526  RDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKG 585

Query: 699  RQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSG 758
              G  G  G  G PG  G +G  G +G++GP+G  GPTGP G +G    TG  G +G  G
Sbjct: 586  NDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGD---TGPPGPQGLQG 642

Query: 759  GDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPG 818
              G  GPPGE G PG  GP G  G  G PG  G  G PG  G  G  G  G  G  GPPG
Sbjct: 643  LPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPG 702

Query: 819  VVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGA---PGKDGPAG 875
              G +GAAG  GP G  G PG  G PGE+G  G+ G +G KG+PG PGA   PGKDGP  
Sbjct: 703  PEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGP-- 760

Query: 876  LRGFPGERGLPGTAGGPGLKGNEGPSGPP---GPAGSPGERGAAGSGGPIGPPGRPGPQG 932
             RG  G  G PG AG PG KG  G  G P   GP GSPGERG  G  GP G PG PG  G
Sbjct: 761  -RGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNG 819

Query: 933  PPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKG 992
             PG  GE+G PGEKG  GP    GV GP G  GPAGPPG  G  G++G  G PG  G  G
Sbjct: 820  EPGGKGERGAPGEKGEGGP---PGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPG 876

Query: 993  NKGEHGPPGP---PGPIGPVGQPGA---------AGADGEPGARGPQGHFGAKGDEGTRG 1040
             +G  GPPG    PGP GP G PG           GA G PG  GP+G  G  G++G+ G
Sbjct: 877  ARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPG 936

Query: 1041 FNGP---PGPIGLQGLPGPSGEKGETGDVGPMGPPGP---------PGPRGPAGPNGADG 1088
              GP   PGP+G+ G+ G  G  G  G  GP G PGP         PG  G +G  G  G
Sbjct: 937  AQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPG 996

Query: 1089 PQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKG 1148
            PQG PG  G  G PG  G PG  G PG  G PG KG RGE G  G  G PG PGPPGP G
Sbjct: 997  PQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVG 1056

Query: 1149 PTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPG 1208
            P G  G +G  GP G  G PGP G  G  G  G +GD+GE GE G  G  G  G  G PG
Sbjct: 1057 PAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPG 1116

Query: 1209 PLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG 1268
              G  GPAG  G+ G  G  G +G  G  G PGK G  G  GP G PGP G RG  GS G
Sbjct: 1117 APGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEG 1176

Query: 1269 QQGRPGATGQAGPPGPVGP-PGLPGLRGDAGAKGEK 1303
              G PG  G  GPPG  GP  G  G    AG  GEK
Sbjct: 1177 SPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEK 1212



 Score =  503 bits (1294), Expect = e-142
 Identities = 300/694 (43%), Positives = 337/694 (48%), Gaps = 110/694 (15%)

Query: 831  PMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAG 890
            P GE     P  P      P   G +G KGDPGPPG PG++G  G+ G PG  G PG  G
Sbjct: 80   PFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPG 139

Query: 891  -------GP-------------------GLKGNEGPSGPPGP------------------ 906
                   GP                   GL G  GP+GPPGP                  
Sbjct: 140  ICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGY 199

Query: 907  AGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGP 966
             G PGE G AG  GP GPPG  GP GP G  GE G PG  G  G  G  G++GP G+PG 
Sbjct: 200  QGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGF 259

Query: 967  AGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGP 1026
             G  G  G DG  GE G+ G  G KG  G  G  G PGP+GP G PG  G  G PGA G 
Sbjct: 260  PGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGA 319

Query: 1027 QGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGA 1086
            +G+ GA+G +G     GPPGP G  G PG  G KGE G  G  G  G PG RG  GP G 
Sbjct: 320  RGNDGARGSDGQ---PGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGH 376

Query: 1087 DGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGP------------RGERGEKGE 1134
             G QGPPG  G  G PG KGE G +G PG  G  G +GP            RG  GE G+
Sbjct: 377  AGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGK 436

Query: 1135 SGQPGEPGPPGPKGPT---GDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGE 1191
            +G  GEPGP G +G     G  G KG  G  G PG+PG  G  G  G+ GA G RG  G 
Sbjct: 437  NGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGP 496

Query: 1192 PGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAP----------- 1240
             G PG  GP GE G PGP G RG AG PG +G  GG G +G PG+ G P           
Sbjct: 497  NGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGS 556

Query: 1241 ----GKTGPVGPAGPAGK---------------PGPDGLRGLPGSVGQQGRPGATGQAGP 1281
                G+ GP GP+GP G+               PG +G RG PG  G QG PG  G+ GP
Sbjct: 557  QGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGP 616

Query: 1282 PGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQ---GEKGDRGLPGPQGSPGQKGE 1338
             GP GP G  G +GD G  G +G  GL G  GPPGE    GE G +G  G  G+PG KG+
Sbjct: 617  QGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGD 676

Query: 1339 MGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1398
             G PG  GP G  G PGL G AGP G +G  G  GP G  G  G PG  G PGE      
Sbjct: 677  AGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGE------ 730

Query: 1399 IQMPKKTRRSVDGSRLMQEDEAIPTG-GAPGSPG 1431
                    R   GS   + D+  P G GA G PG
Sbjct: 731  --------RGGLGSPGPKGDKGEPGGPGADGVPG 756



 Score =  151 bits (381), Expect = 6e-36
 Identities = 108/303 (35%), Positives = 117/303 (38%), Gaps = 71/303 (23%)

Query: 1188 EDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVG 1247
            +D E   P    P GE     P     P   P  +G QG KG  G PG  G  G  G  G
Sbjct: 68   DDQELDCPNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPG 127

Query: 1248 PAGPAGKPGPDGL----------------------------------------------- 1260
              G  G PGP G+                                               
Sbjct: 128  QPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGT 187

Query: 1261 ---RGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGE 1317
                G PGS G QG PG  GQAGP GP GPPG  G  G AG  GE G PG  G  G PG 
Sbjct: 188  SGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGP 247

Query: 1318 QGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGE 1377
             G KG  G+P   G PG KG  G  G +G  G  G PGL G  G  G  GA GP GP+G 
Sbjct: 248  PGIKGPAGIP---GFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGA 304

Query: 1378 KGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP----TGGAPGSPGGL 1433
             G +G PG PG  G               R  DG+R        P    T G PGSPG  
Sbjct: 305  PGERGRPGLPGAAG--------------ARGNDGARGSDGQPGPPGPPGTAGFPGSPGAK 350

Query: 1434 EEI 1436
             E+
Sbjct: 351  GEV 353


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 1023 bits (2645), Expect = 0.0
 Identities = 606/1393 (43%), Positives = 703/1393 (50%), Gaps = 121/1393 (8%)

Query: 297  EGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDK 356
            +GPAG  GP G +G PGP G  GE GP G    PG  G PGPPG       ++   G   
Sbjct: 32   KGPAGDRGPRGERGPPGPPGRDGEDGPTGP---PGPPGPPGPPGLGGNFAAQYDGKGVGL 88

Query: 357  GPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRG 416
            GP                 + L GP GP G  G PGP G  G  G  GE G  GP G RG
Sbjct: 89   GP---------------GPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARG 133

Query: 417  PQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPG 476
            P    GPPGKAG  G  G  G  G  G  G +G RGF G PGLPG KG RG  G  GL G
Sbjct: 134  P---AGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKG 190

Query: 477  PPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQG 536
             PG  G +G+ G  G  G PG++G RGL G +G  G PGP G RG DG  GP G  GP G
Sbjct: 191  QPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIG 250

Query: 537  EPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKG 596
              GPPG  G PG +G  G  G  GP G  GP+G+ GLPG+ G  GPPG+PG  G  G KG
Sbjct: 251  SAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKG 310

Query: 597  NQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV-- 654
              G  G  G  G PGPRG+ G  G  G  G +G  GE G  G KG+ G KG+ G  G   
Sbjct: 311  AAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQG 370

Query: 655  -PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPG 713
             PG  GE+G  GP G  G  G PGPPGL G  G  G+PG  G  G  GP GS G  G  G
Sbjct: 371  PPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAG 430

Query: 714  ASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPG 773
              G  G  G  G+ G  G RG  G  G  GP G  G  G  G  G  GP GP G RG P 
Sbjct: 431  VRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEP- 489

Query: 774  PQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMG 833
              G  GFPGPKGP G PGK+G  GH       G  G  G PGP G  G QG  G  G  G
Sbjct: 490  --GNIGFPGPKGPTGDPGKNGDKGH------AGLAGARGAPGPDGNNGAQGPPGPQGVQG 541

Query: 834  ERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPP------GAPGKDGPAGLRGFPGERGLPG 887
             +G  GPPGPPG QGLPG +G  G  G PG        G PG  GP G RG PGE G  G
Sbjct: 542  GKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAG 601

Query: 888  TAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP---PGAAGEKGVPG 944
              G  G +G  GP GP G  G PG  GA G+ GP GP G PG +G    PG  GEKG PG
Sbjct: 602  PTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPG 661

Query: 945  EKGPIGPTGRDGVQ---GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPG 1001
             +G IG  GRDG +   G VG PGPAG  G  GE G  G  G  G +G+ G +GE GP G
Sbjct: 662  LRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAG 721

Query: 1002 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKG 1061
            P G  GP G  G  GA GE GA+GP+G  G  G  G  G  GP GP    G PGP+G +G
Sbjct: 722  PNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGP---NGPPGPAGSRG 778

Query: 1062 ETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN---LGPPGEKGEPGESGSPGIQG 1118
            + G  G  G PG  G  GP GP+G  GP GPPG  G     GP G++G  G +G  G  G
Sbjct: 779  DGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVG 838

Query: 1119 EPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRG 1178
             PG  G +G  GE G +G PG PGP G  G  G  G  G+ G  G PG  G  GE GP G
Sbjct: 839  PPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLG 898

Query: 1179 QDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIG 1238
              G  G RG  G  G PG  G  GE G  G  G  GP G  G  G +G +G  G+ G +G
Sbjct: 899  IAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVG 958

Query: 1239 APGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAG 1298
            A G  GP GP GPAGK G  G  G  G VG  G  G  G +GP G  G  G PG +G  G
Sbjct: 959  AAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRG 1018

Query: 1299 AKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPG 1358
              G KGH GL GL   PG  G  GD+G PG  G  G +G  G  G +G  G  G PG  G
Sbjct: 1019 LPGLKGHNGLQGL---PGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVG 1075

Query: 1359 PAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQED 1418
            PAG +G +G  GP GP       GPPG PGPPG                   G      D
Sbjct: 1076 PAGIRGPQGHQGPAGP------PGPPGPPGPPG----------------VSGGGYDFGYD 1113

Query: 1419 EAIPTGGAPGSPGGLE----EIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPEL 1474
                    P S   L     E+  +L SL  +IE +  P G++ +PARTC+DL+L HPE 
Sbjct: 1114 GDFYRADQPRSAPSLRPKDYEVDATLKSLNNQIETLLTPEGSRKNPARTCRDLRLSHPEW 1173

Query: 1475 PDGEYWVDPNQGCARDAFRVFCNFTAGGETCVTPRDD----------------------- 1511
              G YW+DPNQGC  DA +V+C+F+  GETC+  + +                       
Sbjct: 1174 SSGYYWIDPNQGCTMDAIKVYCDFST-GETCIRAQPENIPAKNWYRSSKDKKHVWLGETI 1232

Query: 1512 --VTQFSY-VDSEGSPVGVVQLTFLRLLSVSAHQDVSYPCSGA-----ARDGPLR----L 1559
               +QF Y V+   S     QL F+RLL+  A Q+++Y C  +        G L+    L
Sbjct: 1233 NAGSQFEYNVEGVTSKEMATQLAFMRLLANYASQNITYHCKNSIAYMDEETGNLKKAVIL 1292

Query: 1560 RGANEDELSPETSP--YVKEFRDGCQ---TQQGRTVLEVRTPVLEQLPVLDASFSDLGAP 1614
            +G+N+ EL  E +         DGC     + G+T++E +T    +LP LD +  D+G  
Sbjct: 1293 QGSNDVELVAEGNSRFTYTVLVDGCSKKTNEWGKTIIEYKTNKPSRLPFLDIAPLDIGGA 1352

Query: 1615 PRRGGVLLGPVCF 1627
             +   V +GPVCF
Sbjct: 1353 DQEFFVDIGPVCF 1365



 Score =  760 bits (1963), Expect = 0.0
 Identities = 462/1033 (44%), Positives = 518/1033 (50%), Gaps = 123/1033 (11%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 322
            P +  A GP+G +G  GEP   EPG    GP G  GPAG  G  G  G+PG  G PGERG
Sbjct: 102  PGAAGAPGPQGFQGPAGEPG--EPGQT--GPAGARGPAGPPGKAGEDGHPGKPGRPGERG 157

Query: 323  PPGRAGLPGSDGAPGPPGTSLMLPFRFGSG--GGDKGPVVAAQEAQAQAILQQARLALRG 380
              G  G  G  G PG PG   +       G  G    P V  +           +   RG
Sbjct: 158  VVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARG 217

Query: 381  PPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGL---------------TGPPG 425
             PG  G  G PGP G  GS G  G  G  GP G  GP G                 GP G
Sbjct: 218  LPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAG 277

Query: 426  KAGRRGRAGADGARGM---PGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGP---PG 479
             AG RG  G  G  G    PG+PG  G  G  G  GLPG  G  G  G +G+PGP    G
Sbjct: 278  PAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAG 337

Query: 480  EDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG 539
              G RG  GE GP G  GESG +G  G  GP G PGP G  G  GP G  GS GP   PG
Sbjct: 338  ATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGP---PG 394

Query: 540  PPGQQGTPGTQGLPGPQG---AIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGP---PG 593
            PPG +G+PG++GLPG  G    +GP G +G  G  G+ G  G  G PG PG  GP   PG
Sbjct: 395  PPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPG 454

Query: 594  TKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKG---DIGVKGDRG 650
            + GN GP+G +GP+G PG   + G  G  G  G +GE G  GFPG KG   D G  GD+G
Sbjct: 455  SPGNIGPAGKEGPVGLPG---IDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKG 511

Query: 651  EVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPG 710
              G+ G+RG  GP+G  G  GP   PGP G+ G KG+ G PG PG+ G  GP G  G  G
Sbjct: 512  HAGLAGARGAPGPDGNNGAQGP---PGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVG 568

Query: 711  FPGASGEKGARGLSGKSGPRGERGP---------TGPRGQRGPRGATGKSGAKG------ 755
             PG  G  G  GL G +GPRGERGP         TGP G RGP G  G  G KG      
Sbjct: 569  KPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVG 628

Query: 756  ---TSGGDGPHGPPGERG---LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQ-------- 801
               T+G  GP G PGERG   +PG +G  G PG +G  G PG+DG  G PG         
Sbjct: 629  AVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAG 688

Query: 802  -------------------RGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPG 842
                               RG  G +G+ GP GP G  GP GAAG+ G  GERG  GP G
Sbjct: 689  ATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKG 748

Query: 843  PPG---EQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEG 899
              G     G  G AG  G  G PGP G+ G  GP G+ GFPG  G     G PG  G  G
Sbjct: 749  ENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAG---RTGPPGPSGISG 805

Query: 900  PSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQG 959
            P GPPGPAG  G RG  G  GP+G  G  G  GPPG AGEKG  GE G  GP G  G QG
Sbjct: 806  PPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQG 865

Query: 960  PVGLPGPAGPPGVAGE---DGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG 1016
             +G PG  G PG  GE    G  G VG+PG  G  G  G  GPPG  G  G  G PG AG
Sbjct: 866  LLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAG 925

Query: 1017 ADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSG---------EKGETGDVG 1067
             DG PG  GP G  G  G +G RG+ G  GP+G  G PGP G          +GETG  G
Sbjct: 926  RDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSG 985

Query: 1068 PMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGI------QGEPG 1121
            P+GP G  GPRGP+GP G  G +G PG  G  G PG KG  G  G PGI      QG PG
Sbjct: 986  PVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPG 1045

Query: 1122 VKGPRGERGEKGESG---QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRG 1178
              GP G RG  G SG   + G  G PG  GP G  GP+G+ GP G PG PGPP   GP G
Sbjct: 1046 SVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPP---GPPG 1102

Query: 1179 QDGAKGDRGEDGE 1191
              G   D G DG+
Sbjct: 1103 VSGGGYDFGYDGD 1115



 Score =  598 bits (1543), Expect = e-170
 Identities = 367/843 (43%), Positives = 422/843 (50%), Gaps = 89/843 (10%)

Query: 229  EGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGM 288
            E G +  P +  P   Q  P        R  N E  S    GP GL+G  G         
Sbjct: 356  ESGNKGEPGSAGP---QGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGS-------- 404

Query: 289  LVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFR 348
               G PG +G AG++GPPG +G  GP    G RGP G AG PG  G  GP G    LP  
Sbjct: 405  --RGLPGADGRAGVMGPPGSRGASGPA---GVRGPNGDAGRPGEPGLMGPRG----LP-- 453

Query: 349  FGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGD 408
                 G+ GP  A +E               GP G  G  GRPGP+G  G+   +GE G+
Sbjct: 454  --GSPGNIGP--AGKE---------------GPVGLPGIDGRPGPIGPAGA---RGEPGN 491

Query: 409  LGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGD 468
            +G  GP+GP   TG PGK G +G AG  GARG PG  G  G +G  G  G+ G KG +G 
Sbjct: 492  IGFPGPKGP---TGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGP 548

Query: 469  TGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGP 528
             G  G  G PG  G  G+ G+ G RGL GE    GL GP GP G  GPPG  G  GP GP
Sbjct: 549  PGPPGFQGLPGPSGPAGEVGKPGERGLHGEF---GLPGPAGPRGERGPPGESGAAGPTGP 605

Query: 529  KGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGK 588
             GS GP G PGP G +G PG  G  G  G  GP G  G +G  G+PG  G  G PG  G+
Sbjct: 606  IGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGE 665

Query: 589  EGPP---GTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGV 645
             G P   G +G  G  G  GP G  G RG  G  G  G  G +G  GE G  G  G  G 
Sbjct: 666  IGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGF 725

Query: 646  KGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGS 705
             G  G  G PG++GE G +GPKG  G  G  GP G  G  G  G PG  G  G  GP G 
Sbjct: 726  AGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGM 785

Query: 706  LGFPGFPGASGEKGARGLS---GKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGP 762
             GFPG  G +G  G  G+S   G  GP G+ G  GPRG +GP G TG+ GA G  G  G 
Sbjct: 786  TGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGE 845

Query: 763  HGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGP 822
             GP GE G  GP G    PGP+G  G PG  GLPG  G+RG  G  G  G PGP G+ GP
Sbjct: 846  KGPSGEAGTAGPPGT---PGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGP 902

Query: 823  QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE 882
             GA         RG PG  G PG  G PG AG++G  G+ GPPG  G+ G  G RG+PG 
Sbjct: 903  PGA---------RGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGN 953

Query: 883  RGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGV 942
             G  G AG P      GP GP GPAG  G RG  G  GP+GP G  GP+GP G  G +G 
Sbjct: 954  IGPVGAAGAP------GPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGD 1007

Query: 943  PGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGP 1002
             GE G  GP G  G++G  GL    G PG+AG  GD+G  G  G  G +      GP GP
Sbjct: 1008 KGEPGEKGPRGLPGLKGHNGL---QGLPGIAGHHGDQGAPGSVGPAGPR------GPAGP 1058

Query: 1003 PGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGE 1062
             GP G  G+ G  G  G  G RGPQGH      +G  G  GPPGP G  G+ G   + G 
Sbjct: 1059 SGPAGKDGRTGHPGTVGPAGIRGPQGH------QGPAGPPGPPGPPGPPGVSGGGYDFGY 1112

Query: 1063 TGD 1065
             GD
Sbjct: 1113 DGD 1115



 Score =  303 bits (776), Expect = 9e-82
 Identities = 191/480 (39%), Positives = 215/480 (44%), Gaps = 107/480 (22%)

Query: 1051 QGLPGPSGEKGETGDVGPMGPPGPPGP------RGPAGPNGADGPQGPPGGVGNL----- 1099
            Q L   +  KG  GD GP G  GPPGP       GP GP G  GP GPPG  GN      
Sbjct: 23   QSLQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYD 82

Query: 1100 -----------------GPPGEKGEP---------GESGSPGIQGEPGVKGPRGERGEKG 1133
                             GPPG  G P         GE G PG  G  G +GP G  G+ G
Sbjct: 83   GKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAG 142

Query: 1134 ESGQPGEPGPPGPKGPTGD------------------------DGPKGNPGPVGFPGDPG 1169
            E G PG+PG PG +G  G                         DG KG PG  G  G+PG
Sbjct: 143  EDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPG 202

Query: 1170 PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKG 1229
             PGE G  GQ GA+G  GE G  G PG  G  G +G  GP+G  GP GS G  G  G  G
Sbjct: 203  APGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPG 262

Query: 1230 AKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPG 1289
             KG+ GA+G  G  GP GP G  G PG  G  G PG+ G  G  GA G AG PG  G PG
Sbjct: 263  PKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPG 322

Query: 1290 LPGLR---------------------GDAGAKGE---KGHPGLIGLIGPPGEQGEKGDR- 1324
            LPG R                     G AG+KGE   KG PG  G  GPPG  GE+G R 
Sbjct: 323  LPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRG 382

Query: 1325 --------GLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKG 1376
                    G PGP G  G  G  G+PGA G  G  GPPG  G +GP G +G  G  G  G
Sbjct: 383  PNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPG 442

Query: 1377 EKGVQGPPGHPGPPGEV---IQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGL 1433
            E G+ GP G PG PG +    +  P+ +P      +DG         I   GA G PG +
Sbjct: 443  EPGLMGPRGLPGSPGNIGPAGKEGPVGLP-----GIDG-----RPGPIGPAGARGEPGNI 492


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  993 bits (2567), Expect = 0.0
 Identities = 599/1343 (44%), Positives = 679/1343 (50%), Gaps = 214/1343 (15%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 322
            P  Q   GP G+ G KGEP      +++   PGP+G  G  GPPGIQG PGP G PG  G
Sbjct: 140  PGLQGPPGPPGIPGMKGEPG----SIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIG 195

Query: 323  PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPP 382
            PPG  GL G  G PG PG    +   F    G+KG                    L+GPP
Sbjct: 196  PPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKG-----------------EQGLQGPP 238

Query: 383  GPMGYT----------------GRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGK 426
            GP G                  G PG  G PG PG++G  G   P G +G +G  G PGK
Sbjct: 239  GPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGP--PGGEKGEKGEQGEPGK 296

Query: 427  AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPG----PPGEDG 482
               RG+ G DG  G PG PG+ GD G+ G PG  GEKG +GDTG  G PG     PG   
Sbjct: 297  ---RGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGI 353

Query: 483  ERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGE----- 537
              G+ G IG  GLPGE G RG  G +GPPG+PGPPG   M GP GP G  G +G+     
Sbjct: 354  TIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM-GPPGPPGFPGERGQKGDEG 412

Query: 538  ------PGPPGQQGTPGTQGLPGPQGAIGPH-------GEKGPQGKPGLPG--------- 575
                  PGPPG  G PG  GLPGP G  GPH        E GP G PG PG         
Sbjct: 413  PPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQG 472

Query: 576  ----------------MPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVD 619
                            + G  G PG PG  GPPG+ G  G  G +G  G  GP+G+ G+ 
Sbjct: 473  VKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIP 532

Query: 620  GIRGLKGHKGEKGEDG----FPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGD 675
            G  G  G  G KGE G    FPG KGD G  G  G  G+PG  G  G +G  G  GP G+
Sbjct: 533  GAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGE 592

Query: 676  PGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGP 735
            PG     GE+G  G PGLPG PG  GP G  GF G PG  GEKG +G++G  G  G  GP
Sbjct: 593  PGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGP 651

Query: 736  TGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKG---------- 785
             G  GQ   +   GK G  G  G DG  G PG+ GLPG  G  G PG KG          
Sbjct: 652  KGDPGQTITQ--PGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLP 709

Query: 786  -PPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAG----------------- 827
             PPGP G  G+PG PG  G  G  G  GPPGPPG  GP+G  G                 
Sbjct: 710  GPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG 769

Query: 828  ETGPMGERGHPGPPGPPGE---QGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERG 884
              GP G+RG PGPPGPPG     GLPG  G  G  G PGP G PG  G  G++G PG  G
Sbjct: 770  ALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG-IGVQGPPGPPG 828

Query: 885  LPGTAGGPGLKGNEGPSGPPGPAG-----SPGERGAAGSGGPIGPPGRPGPQGPPGAAGE 939
            +PG  G PGL G  G  G PGP G      PGERG+ G  G  GP G PG  G PG AG 
Sbjct: 829  IPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGA 888

Query: 940  KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 999
             G PG KG +G  G  G  GP+G+PG +G PG+ G+DG +G+ G PG  G KG+KGE G 
Sbjct: 889  SGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGL 948

Query: 1000 PGPPGPIGP-----VGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNG------PPGPI 1048
            PGPPGP+ P      G+ G  G  G PG  GP+G+ G  GD G  G +G      PPGP 
Sbjct: 949  PGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPK 1008

Query: 1049 GLQGLPGPSG---EKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG----------- 1094
            G  GLPG  G     G  G +G MG PGP G  GP GP+G  G  G PG           
Sbjct: 1009 GNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDP 1068

Query: 1095 GVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERG---------EKGESGQPGEPGPPG 1145
            G+ ++G PG  G  GE G PG  G PG+KG  G+ G          KG+ G PG PG PG
Sbjct: 1069 GISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPG 1128

Query: 1146 PKGPTGDDGPKGNPG------PVG---FPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG 1196
            P GP G  GP GNPG      PVG    PG PGPPGE G  GQDG  G  G+ GEPGQPG
Sbjct: 1129 PPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG 1188

Query: 1197 SPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG 1256
               P G  G PG  G++G  G PG  G  G  G KG+PG  G PG  GP GP G  G P 
Sbjct: 1189 FGNP-GPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG-PA 1246

Query: 1257 PDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL----- 1311
             +G +G PG  G  GRPG TG  G PGP GPPGLPG  G  G KG  G PGL GL     
Sbjct: 1247 LEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKG 1306

Query: 1312 -IGPPGEQGE---------KGDRGLPGPQGSPGQKGEMGIPGASGP------IGPGGPPG 1355
              GPPG QG          KGD GLPG  G PG KG  G+PG++GP      IGP GPPG
Sbjct: 1307 DQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPG 1366

Query: 1356 LPGPAGPK-------GAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRS 1408
            LPGP+G         G  G  G  G KG  G QGP G PGP G    P    +P      
Sbjct: 1367 LPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP-----G 1421

Query: 1409 VDGSRLMQEDEAIPTGGAPGSPG 1431
             DG+   + D  +P  G PG+ G
Sbjct: 1422 FDGAGGRKGDPGLP--GQPGTRG 1442



 Score =  879 bits (2272), Expect = 0.0
 Identities = 546/1247 (43%), Positives = 625/1247 (50%), Gaps = 164/1247 (13%)

Query: 237  QNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGP 296
            + +Q  +    P  Q S   RP + E Q     G +GL G++G P    PG  + GPPGP
Sbjct: 229  KGEQGLQGPPGPPGQISEQKRPIDVEFQK----GDQGLPGDRGPPG--PPG--IRGPPGP 280

Query: 297  EGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--G 354
              P G  G  G QG PG  G PG+ G  G+ G+PG  G PG PG     P R G  G  G
Sbjct: 281  --PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGE----PGRDGEKGQKG 334

Query: 355  DKGP-----VVAAQEAQAQAILQQARLAL---------RGPPGPMGYTGRPGP-----LG 395
            D GP     +V  +      I ++  + L         RG PG  G  G PGP     +G
Sbjct: 335  DTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMG 394

Query: 396  QPGSPGLKGESGDLGPQGPRG-----PQGLTGPPGKAGRRGRAGADGAR----------G 440
             PG PG  GE G  G +GP G     P GL G PG  G  G  G  G            G
Sbjct: 395  PPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPG 454

Query: 441  MPGDPGVKGDRGFDGLPGLPGEKGHR----------GDTGAQGLPGPPGEDGERGDDGEI 490
             PG PG  GD+G  G  G+ G+KG            G  G  GLPG PG  G  G  G+ 
Sbjct: 455  PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQK 514

Query: 491  GPRGLPGESGPRGLLGPKGPPGIPGPPGVRG-------MDGPQGPKGSLGPQGEPGPPGQ 543
            G +G  G +GP+GL G  G PG PG PG +G         G +G KG LG  G PG PG 
Sbjct: 515  GEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGL 574

Query: 544  QGTPGTQGLPGPQGAIGP------HGEKGPQGKPGLPGMPGSDGPPGHPG--KEGPPGTK 595
             GTPG  GLPG  G  G        GE+GP G PGLPG+PG+ GP G PG    GP G K
Sbjct: 575  PGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEK 634

Query: 596  GNQGPSGPQGPLGYPGPRGVKGVDGIR-GLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV 654
            G QG +G  G  G PGP+G  G    + G  G  G  G DG  G  GD G+ G  G  G+
Sbjct: 635  GIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGI 694

Query: 655  PGSRGEDG--------PEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQG----- 701
            PGS+GE G        P GPKG  G  G PG PG  G  G  G PG PG+PG +G     
Sbjct: 695  PGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFA 754

Query: 702  ---PKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSG 758
               P G  G PGF GA G KG RG  G  GP G  G  G  G +G  G  G+ G  G  G
Sbjct: 755  LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPG 814

Query: 759  --GDGPHGPPGERGLPGPQGP---NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGP 813
              G G  GPPG  G+PGP G    +G PG KG PGPPG D +PG PG+RG  G  G  GP
Sbjct: 815  LPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLD-VPGPPGERGSPGIPGAPGP 873

Query: 814  ---PGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGK 870
               PG PG+ G  GA+G  G  GE G  GPPGPPG  G+PG +G  G KGD G  G PG 
Sbjct: 874  IGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGL 933

Query: 871  DGPAGLRGFPGERGLPGTAG--GPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP 928
             GP G +G  GE GLPG  G   P L G++G  G PG  G PG  G  G  G  G PG+P
Sbjct: 934  PGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQP 993

Query: 929  GPQG------PPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAG---PPGVAGEDGDK 979
            G  G      PPG  G  G+PG+ G IGP G  G  G +G PGP G   PPG +G  G  
Sbjct: 994  GLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQP 1053

Query: 980  GEVGDPGQKGTKGNKGEH--------GPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFG 1031
            G  G PGQKG KG+ G          GP G PG  G  G PG  G+ G+PG  G  G  G
Sbjct: 1054 GSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPG 1113

Query: 1032 AKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMG------PPGPPGPRGPAGPNG 1085
            AKG  G  GF G PGP G +G+ GP G  G  G+ GP+G       PGPPG +G  G +G
Sbjct: 1114 AKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDG 1173

Query: 1086 ADGPQGPPG-----GVGNLGPPGE---KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQ 1137
              GP G  G     G GN GPPG     G+ G+ G PGI G PG+ GP+GE G  G  G 
Sbjct: 1174 IPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGV 1233

Query: 1138 PGEPGPPG--------PKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGED 1189
             G PGPPG        PKG  G  GP G PGP GF G PGP G  G  G  G KG++G  
Sbjct: 1234 QGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNP 1293

Query: 1190 GEPGQPGSPGPTGENGPPGPLGK---------RGPAGSPGSEGRQGGKGAKGDPGAIGAP 1240
            G+PG PG PG  G+ GPPG  G          +G  G PG  G  G KG  G PG+ G  
Sbjct: 1294 GQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPE 1353

Query: 1241 GKTGPVGPAGPAGKPGPDGLR----------GLPGSVGQQGRPGATGQAGPPGPVGPPGL 1290
            G+ G +GP GP G PGP G            G+PG  G +G PG  G  G PGP GPPG 
Sbjct: 1354 GEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGD 1413

Query: 1291 P---GLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPG 1334
            P   GL G  GA G KG PGL G  G  G  G  G  GL GP G PG
Sbjct: 1414 PGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460



 Score =  819 bits (2115), Expect = 0.0
 Identities = 491/1070 (45%), Positives = 556/1070 (51%), Gaps = 115/1070 (10%)

Query: 446  GVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLL 505
            G+KG++G  G PGL   +GH G  G  G  GPPG  G++GDDG      +PG  GP+G+ 
Sbjct: 42   GIKGEKGERGFPGL---EGHPGLPGFPGPEGPPGPRGQKGDDG------IPGPPGPKGIR 92

Query: 506  GPKGPPGIPGPPGVRGM------DGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAI 559
            GP G PG PG PG+ GM       GPQG  G  G +GE G PG  G PG QG PGP G  
Sbjct: 93   GPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIP 152

Query: 560  GPHGE---------KGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYP 610
            G  GE          GP+G PG PG PG  G PG  G  GP G  G  G  GP GP G P
Sbjct: 153  GMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLP 212

Query: 611  GPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIG-------VKGDRGEVGVPGSRGEDGP 663
            GP+G  G++  +G KG KGE+G  G PG  G I        V+  +G+ G+PG R   GP
Sbjct: 213  GPKGNMGLN-FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDR---GP 268

Query: 664  EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 723
             GP G  GP G PG  G  GEKG+ G PG  G PG+ G  G  G PG PG  G  G  G 
Sbjct: 269  PGPPGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326

Query: 724  SGKSGPRGERGPTGPRGQRGPRGATGKS-GAKGTSGGDGPHGPPGERGLPGPQGPNGFPG 782
             G+ G +G+ GP GP G   PR  TG + G KG  G  G  G  GERG PG QGP G PG
Sbjct: 327  DGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPG 386

Query: 783  PKGPP--GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERG---- 836
            P G    GPPG  G PG  GQ+G+ G  G    PGPPG+ G  GA G  GP G  G    
Sbjct: 387  PPGAAVMGPPGPPGFPGERGQKGDEGPPG-ISIPGPPGLDGQPGAPGLPGPPGPAGPHIP 445

Query: 837  ------HPGPPGPPGEQGLPGTAGKEGTKGDPGPPG----APGKDGPAGLRGFPGERGLP 886
                   PGPPGPPG  G  G  G++G KGD G         G  GP G  G PG  G P
Sbjct: 446  PSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPP 505

Query: 887  GTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGP----QGPPGAAGEKGV 942
            G+ G PG KG +G +G  GP G PG  GA G+ G  G  G PG      G  G  GE G 
Sbjct: 506  GSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGS 565

Query: 943  PGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPP-- 1000
            PG  G  G  G  G  G  GLPGP G PG     G++G  G+PG  G  GN G  GPP  
Sbjct: 566  PGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF 625

Query: 1001 GPPGPIGPVGQPGAAGADGEPGARGPQGHFGA-------------KGDEGTRGFNGPPGP 1047
            GPPGP+G  G  G AG  G+PG  GP+G  G               G +G  G  G PG 
Sbjct: 626  GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGL 685

Query: 1048 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1107
             G  GLPG  G KGE G  G +G PGPPGP+G  G  G  G  G PG +G  GPPG  G 
Sbjct: 686  PGQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGF 744

Query: 1108 PGESGSPGI-----QGEPGVKGPRGERGEKGESGQPGEPGPPGP------KGPTGDDGPK 1156
            PG  G PG       G PG+ G +G  G KG+ G PG PGPPG        GP GD GP 
Sbjct: 745  PGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804

Query: 1157 GNPGPVGFP--------GDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG--SPGPTGENGP 1206
            G PGP+G P        G PGPPG  GP GQ G  G  GE G+PG PG   PGP GE G 
Sbjct: 805  GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGS 864

Query: 1207 PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGS 1266
            PG  G  GP G PGS G  G  GA G PG  G  G  GP GP GP G PG  G+ GL G 
Sbjct: 865  PGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924

Query: 1267 VGQQGRPGATGQAGPPGPVGPPGLPGLRGD-----AGAKGEKGHPGLIGLIGPPGEQGEK 1321
             G QG+PG  G  G  G  G PGLPG  G       G+KGEKG PGL G+   PG  G K
Sbjct: 925  DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGI---PGVSGPK 981

Query: 1322 GDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQ 1381
            G +GLPG  G PG  G+ G+PG  GP G  G PG PG  GP G KG  G  G  G +GV+
Sbjct: 982  GYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVE 1041

Query: 1382 GPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1431
            GPPG  G PG+   P            + G +  + D  I + G PG PG
Sbjct: 1042 GPPGPSGVPGQPGSP-----------GLPGQKGDKGDPGISSIGLPGLPG 1080



 Score =  778 bits (2010), Expect = 0.0
 Identities = 465/1038 (44%), Positives = 533/1038 (51%), Gaps = 117/1038 (11%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 322
            P  +   G +G+KG+KG+      G  + GPPG  G  GL GPPG  G PG  G+ G+ G
Sbjct: 462  PGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAG 521

Query: 323  PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKG-----PVVAAQEAQAQAILQQARLA 377
              G  GLPG  GAPG PG        F    G+ G     P +   + +  +        
Sbjct: 522  ATGPKGLPGIPGAPGAPG--------FPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573

Query: 378  LRGPPGPMGYTGRPGPLGQPG------------SPGLKGESGDLGPQGPRGPQGLTGPPG 425
            L G PG  G  G PGP G+PG            +PGL G  G++GP GP G     GPPG
Sbjct: 574  LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG----FGPPG 629

Query: 426  KAGRRGRAGADGARGMPGDPGVKGDRGFD----GLPGLPGEKGHRGDTGAQGLPGPPGED 481
              G +G  G  G  G PG PG KGD G      G PGLPG  G  GD G  G PG PG+ 
Sbjct: 630  PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689

Query: 482  GERGDDGEIGPRG-----LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQG 536
            G  G  G  G  G     LPG  GP+G  G  GPPG PG PG  G++GP GP G  GP+G
Sbjct: 690  GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG 749

Query: 537  EPG-----PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG---PPGHPGK 588
            EPG     PPG  G PG +G  GP+G  G  G  GP G+ GL G+PG  G   P G PG 
Sbjct: 750  EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGP 809

Query: 589  EGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGED--GFPGFKGDIGVK 646
             GPPG  G  G  GP GP G PGP G  G+ GI G KG  G  G D  G PG +G  G+ 
Sbjct: 810  MGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIP 868

Query: 647  GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL 706
            G  G +G PGS G  G  G  G  G  G+ G  G  G  G LG+PG  G PG +G  G  
Sbjct: 869  GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ 928

Query: 707  GFPGFPGASGEKGARGLSGKSGPRGERGPT--GPRGQRGPRGATGKSGAKGTSGGDGPHG 764
            G PG PG +GEKG++G  G  GP G   P   G +G++G  G  G  G  G  G  G  G
Sbjct: 929  GQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPG 988

Query: 765  PPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGF------QGKTGPPGPPG 818
             PG+ GL G  G  G PGPKG PG PG+ GL G PG +G +G       QG  GPPGP G
Sbjct: 989  DPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSG 1048

Query: 819  VVGPQGAAGETGPMGERGHPGP--------PGPPGEQGLPGTAGKEGTKGDPGPPGAPGK 870
            V G  G+ G  G  G++G PG         PGP GE GLPG  G  G KG  G PG PG 
Sbjct: 1049 VPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGL 1108

Query: 871  DGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGP 930
             G  G +G PG  G PGT G PG KG    SGPPG  G PGE G  G GG    PG+PGP
Sbjct: 1109 PGTPGAKGQPGLPGFPGTPGPPGPKGI---SGPPGNPGLPGEPGPVGGGGH---PGQPGP 1162

Query: 931  QGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGT 990
             G  G  G+ G+PG  G  G  G+ G     G PGP G PG++G+ GD G  G PG  G 
Sbjct: 1163 PGEKGKPGQDGIPGPAGQKGEPGQPGF----GNPGPPGLPGLSGQKGDGGLPGIPGNPGL 1218

Query: 991  KGNKGE---HGPPGPPGPIGPVGQPGAA--GADGEPGARGPQGHFGAKGDEGTRGFNGPP 1045
             G KGE   HG PG  GP GP G PG A  G  G PG +GP G        G  GF G P
Sbjct: 1219 PGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGR------PGPTGFQGLP 1272

Query: 1046 GPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEK 1105
            GP G  GLPG  G KGE G+ G  G PG PG +G          QGPPG  GN G PG  
Sbjct: 1273 GPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGD---------QGPPGLQGNPGRPGLN 1323

Query: 1106 GEPGESGSPGIQGEPGVKGPRGERGEKGESGQPG---EPGPPGPKGPTG-------DDGP 1155
            G  G+ G PG+ G PG+KGP G  G  G  G+PG    PGPPG  GP+G       D GP
Sbjct: 1324 GMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGP 1383

Query: 1156 KGNPG------------PVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGE 1203
             G PG            P G PG  GPPG+ G  G  G  G  G  G+PG PG PG  G 
Sbjct: 1384 PGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGL 1443

Query: 1204 NGPPGPLGKRGPAGSPGS 1221
            +GPPGP G +GP G PG+
Sbjct: 1444 DGPPGPDGLQGPPGPPGT 1461



 Score =  565 bits (1455), Expect = e-160
 Identities = 354/824 (42%), Positives = 404/824 (49%), Gaps = 152/824 (18%)

Query: 262  EPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPG---------IQGNP 312
            +P      G  G+ G KGEP +  PG+ + GPPGP+G  G+ GPPG         ++G P
Sbjct: 682  DPGLPGQPGLPGIPGSKGEPGI--PGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPP 739

Query: 313  GPVGDPGERG--------PPGRAGLPGSDGA---------PGPPGTSLMLPFRFGSGG-- 353
            GP G PG +G        PPG  GLPG  GA         PGPPG     P R G  G  
Sbjct: 740  GPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGP----PGRTGLDGLP 795

Query: 354  GDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQG 413
            G KG V    +           + ++GPPGP G    PGP+GQPG  G+ GE GD GP G
Sbjct: 796  GPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI---PGPIGQPGLHGIPGEKGDPGPPG 852

Query: 414  --------------------PRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG------- 446
                                P GP G  G PGKAG  G  G  G  GM G PG       
Sbjct: 853  LDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGI 912

Query: 447  --------VKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED-----GERGDDGEIGPR 493
                    +KGD G  G PGLPG  G +G  G  GLPGPPG       G +G+ GE G  
Sbjct: 913  PGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLP 972

Query: 494  GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG---PPGQQGTPGTQ 550
            G+PG SGP+G  G  G PG PG  G  G+ GP GPKG+ G  G+PG   PPG +GT G  
Sbjct: 973  GIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDM 1032

Query: 551  GLPGPQGAIGPHGEKG--------------------------------PQGKPGLPGMPG 578
            G PGPQG  GP G  G                                P+G+PGLPG PG
Sbjct: 1033 GFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPG 1092

Query: 579  ------SDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 632
                  S G PG PG  G PG KG  G  G  G  G PGP+G+ G  G  GL G  G  G
Sbjct: 1093 NPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVG 1152

Query: 633  EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 692
              G PG  G  G KG  G+ G+PG  G+ G  G  G   P G PG PGL G+KG  G+PG
Sbjct: 1153 GGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNP-GPPGLPGLSGQKGDGGLPG 1211

Query: 693  LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKS--GPRGERGPTGPRGQRGPRGATGK 750
            +PG PG  GPKG  GF GFPG  G  G  G  G +  GP+G  GP GP G+ GP G  G 
Sbjct: 1212 IPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGL 1271

Query: 751  SGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGK 810
             G +G  G  G  G  GE+G PG  G  G PG KG  GPPG  G PG PG  G  G  G 
Sbjct: 1272 PGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGL 1331

Query: 811  TGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT-KGDPGPPGAPG 869
             G PG PG+ GP G  G  GP GE G  GPPGPPG   LPG +G+    KGD GPPG PG
Sbjct: 1332 PGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPG---LPGPSGQSIIIKGDAGPPGIPG 1388

Query: 870  KDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPG 929
            +         PG +GLPG  G  GL G   P+GPPG  G  G  G  G+GG  G PG PG
Sbjct: 1389 Q---------PGLKGLPGPQGPQGLPG---PTGPPGDPGRNGLPGFDGAGGRKGDPGLPG 1436

Query: 930  PQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA 973
                         PG +G  GP G DG+QGP   PGP G   VA
Sbjct: 1437 Q------------PGTRGLDGPPGPDGLQGP---PGPPGTSSVA 1465



 Score =  559 bits (1440), Expect = e-159
 Identities = 357/848 (42%), Positives = 405/848 (47%), Gaps = 159/848 (18%)

Query: 736  TGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL 795
            +G +G++G RG  G  G  G  G  GP GPPG RG  G  G  G PGPKG  GPP   GL
Sbjct: 41   SGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPP---GL 97

Query: 796  PGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGK 855
            PG PG  G  G  G  G PGP G+ G  G  GE G  G  G PG  GPPG  G+PG  G+
Sbjct: 98   PGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGE 157

Query: 856  EGT---KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP---PGPAGS 909
             G+      PGP G PG  GP G++G PG  G+PG  G PG  G  GP GP   PGP G+
Sbjct: 158  PGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGN 217

Query: 910  --------PGERGAAGSGGPIGPPGR-------------------PGPQGPPGAAGEKGV 942
                     GE+G  G  GP GPPG+                   PG +GPPG  G +G 
Sbjct: 218  MGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP 277

Query: 943  P----GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHG 998
            P    GEKG  G  G  G +G  G  G  G PG+ G  GD G  G+PG+ G KG KG+ G
Sbjct: 278  PGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTG 337

Query: 999  PPGPPGPI-------------GPVGQPGAAGADGE---------------PGA--RGPQG 1028
            PPGPPG +             G +G PG  G  GE               PGA   GP G
Sbjct: 338  PPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG 397

Query: 1029 HFGAKGDEGTRGFNGP-----PGPIGLQGLPGPSGEKGETGDVGPMGP-------PGPPG 1076
              G  G+ G +G  GP     PGP GL G PG  G  G  G  GP  P       PGPPG
Sbjct: 398  PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG 457

Query: 1077 PRGPAGPNGADGPQGPPG----------GVGNLGPPGEKGEPGESGSPGIQGEPGVKGPR 1126
            P G  G  G  G QG  G          G G  GPPG+ G PG  G PG  G PG KG +
Sbjct: 458  PPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEK 517

Query: 1127 GERGEKGESGQPGEPGPPGP----------------KGPTGDDGPKGNPGPVGFPGDPGP 1170
            G+ G  G  G PG PG PG                  G  GD G  G+PG  G PG PG 
Sbjct: 518  GQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT 577

Query: 1171 PGEG------GPRGQDGA---KGDRGEDGEPGQPGSPGPTGEN-----GPPGPLGKRGPA 1216
            PG+       GP+G+ G    KG+RG  G PG PG PG  G       GPPGP+G++G  
Sbjct: 578  PGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQ 637

Query: 1217 GSPGSEGRQGGKGAKGDPGAI----------GAPGKTGPVGPAGPAGKPGPDGLRGLPGS 1266
            G  G+ G+ G  G KGDPG            G PG+ G VG  G  G PG  GL G+PGS
Sbjct: 638  GVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGS 697

Query: 1267 VGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRG- 1325
             G+ G PG     G PGP GP G PG+ G  GA G  G  GL G  GPPG  G KG+ G 
Sbjct: 698  KGEPGIPG----IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF 753

Query: 1326 -LPGPQGSP---------GQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPK 1375
             LPGP G P         G KG+ G PG  GP G  G  GLPGP G  G  G  GP GP 
Sbjct: 754  ALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPP 813

Query: 1376 GEK--GVQGPPGHPGPPGEVIQP----LPIQM--PKKTRRSVDGSRLMQEDEAIPTG--- 1424
            G    GVQGPPG PG PG + QP    +P +   P      V G    +    IP     
Sbjct: 814  GLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGP 873

Query: 1425 -GAPGSPG 1431
             G PGSPG
Sbjct: 874  IGPPGSPG 881



 Score =  514 bits (1324), Expect = e-145
 Identities = 309/707 (43%), Positives = 352/707 (49%), Gaps = 109/707 (15%)

Query: 789  PPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQG 848
            P  K    G  G++GE GF G  G PG PG  GP+G  G  G  G+ G PGPPGP G +G
Sbjct: 34   PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRG 93

Query: 849  LPGTAGKEGTKGDPGPP---GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPG 905
             PG  G  GT G PG P   GAPG  G  G  G  GERG PG+ G PGL+G  GP G PG
Sbjct: 94   PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPG 153

Query: 906  PAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPG 965
              G PG    +   GP G PG PGP G  G  G  G+PG  GP GP G  G  GP GLPG
Sbjct: 154  MKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPG 213

Query: 966  P--------AGPPGVAGEDGDKGEVGDPG-------------QKGTKGNKGEHGPPGPPG 1004
            P         GP G  GE G +G  G PG             QKG +G  G+ GPPGPPG
Sbjct: 214  PKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273

Query: 1005 PIGPVGQPGA-AGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET 1063
              GP G PG   G  GE G  G +G  G  G+ G  G  G PG  G  G PG  GEKG+ 
Sbjct: 274  IRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQK 333

Query: 1064 GDVGPMGPP-------------------GPPGPRGPAGPNGADGPQGPPG-----GVGNL 1099
            GD GP GPP                   G PG  G  G  G  G QGPPG     G   +
Sbjct: 334  GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM 393

Query: 1100 GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN- 1158
            GPPG  G PGE G  G +G PG+  P    G  G  GQPG PG PGP GP G   P  + 
Sbjct: 394  GPPGPPGFPGERGQKGDEGPPGISIP----GPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449

Query: 1159 ---PGPVGFPGDPGPPGEGGPRGQDGAKGDRGE-------------DGEPGQPGSPGPTG 1202
               PGP   PG PG PG+ G +G+ G KGD+G+              G+PG PG PGP G
Sbjct: 450  ICEPGP---PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPG 506

Query: 1203 ENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPV-------GPAGPAGKP 1255
              G PG  G++G AG+ G +G  G  GA G PG  G+ G+ G +       G  G  G P
Sbjct: 507  SLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSP 566

Query: 1256 GPDGLRGLPGSVGQQGRPGATGQAGPP---------GPVGPPGLPGLRGDAGAK------ 1300
            G  GL GLPG+ GQ G PG  G  G P         GP G PGLPGL G+ G        
Sbjct: 567  GAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFG 626

Query: 1301 -----GEKGHPGLIGLIGPPGEQGEKGD-------RGLPGPQGSPGQKGEMGIPGASGPI 1348
                 GEKG  G+ G  G PG  G KGD        G PG  G+PG+ G++G+PG  G  
Sbjct: 627  PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP 686

Query: 1349 GPGGPPGLPGPAGPKGAK--GATGPGGPKGEKGVQGPPGHPGPPGEV 1393
            G  G PG+PG  G  G    G  GP GPKG  G+ GPPG PG PG +
Sbjct: 687  GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRI 733



 Score =  377 bits (967), Expect = e-104
 Identities = 245/607 (40%), Positives = 281/607 (46%), Gaps = 117/607 (19%)

Query: 270  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 329
            G  G  G KGE  ++ P     GPPGP G  G  G PG++G+ G  G PG  GP G  G 
Sbjct: 887  GASGFPGTKGEMGMMGP----PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGS 942

Query: 330  PGSDGAPGPPGTSLMLPFRFGSGG--------------GDKGPVVAAQEAQAQAILQQAR 375
             G  G PGPPG   M P   GS G              G KG      +     +  Q  
Sbjct: 943  KGEPGLPGPPGP--MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQP- 999

Query: 376  LALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGA 435
              L GPPGP G  G PG  G  G PGLKG  GD+G  GP+G +G  GP G  G+ G  G 
Sbjct: 1000 -GLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGL 1058

Query: 436  DGARGMPGDPGVK--------GDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDD 487
             G +G  GDPG+         G +G  GLPG PG  G +G  G  GLPG PG  G +G  
Sbjct: 1059 PGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQP 1118

Query: 488  GEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV------RGMDGPQGPKGSLGPQGEPGPP 541
            G  G  G PG  GP+G+ GP G PG+PG PG        G  GP G KG  G  G PGP 
Sbjct: 1119 GLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPA 1178

Query: 542  GQQGTPGTQGL--PGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPG------KEGPPG 593
            GQ+G PG  G   PGP G  G  G+KG  G PG+PG PG  GP G PG       +GPPG
Sbjct: 1179 GQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPG 1238

Query: 594  TKGNQGPS--------GPQGPLGYPGPRGVKGVDG------------IRGLKGHKGEKGE 633
              G+ GP+        GPQGP G PGP G +G+ G            I+G KG+ G+ G 
Sbjct: 1239 PPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGL 1298

Query: 634  DGFPGFKGDIG---------------VKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG- 677
             G PG KGD G               +KGD G  GVPG  G  GP G  G  GP G+PG 
Sbjct: 1299 PGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGL 1358

Query: 678  -----PPGL----------------------MGEKGKLGVPGLPGYPGRQGPKGS---LG 707
                 PPGL                       G KG  G  G  G PG  GP G     G
Sbjct: 1359 IGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNG 1418

Query: 708  FPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG-------AKGTSGGD 760
             PGF GA G KG  GL G+ G RG  GP GP G +GP G  G S         + +   D
Sbjct: 1419 LPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTD 1478

Query: 761  GPHGPPG 767
             P  P G
Sbjct: 1479 APQCPQG 1485



 Score =  289 bits (739), Expect = 2e-77
 Identities = 174/390 (44%), Positives = 212/390 (54%), Gaps = 25/390 (6%)

Query: 248  PQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVL-EPGML-VEGPPGPEGPAGLIGP 305
            P+ +P     P N  P  + + G  GL G  G P    +PG+    G PGP GP G+ GP
Sbjct: 1081 PKGEPGLPGYPGN--PGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGP 1138

Query: 306  PG---IQGNPGPVGD---PGERGPPGRAGLPGSDGAPGPPGTSLMLPFR--FGSGGGDKG 357
            PG   + G PGPVG    PG+ GPPG  G PG DG PGP G     P +  FG+ G    
Sbjct: 1139 PGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGE-PGQPGFGNPGPPGL 1197

Query: 358  PVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGP 417
            P ++ Q+             L GP G  G+ G PG  G PG PG  G + + GP+G  GP
Sbjct: 1198 PGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALE-GPKGNPGP 1256

Query: 418  QGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDG---LPGLPGEKGHRGDTGAQGL 474
            QG  G PG  G +G  G +G  G+PG+ G+KG++G  G   LPGLPG KG +G  G QG 
Sbjct: 1257 QGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGN 1316

Query: 475  PGPPGEDGERGDDGEIGPRGLPGESGPRGL---LGPKGPPGIPGPPGVRGMDGPQGPKGS 531
            PG PG +G +GD G  G  G PG  GP G+    GP+G PG+ GPPG  G+ GP G   S
Sbjct: 1317 PGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQ--S 1374

Query: 532  LGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKP---GLPGMPGSDGPPGHPGK 588
            +  +G+ GPPG  G PG +GLPGPQG  G  G  GP G P   GLPG  G+ G  G PG 
Sbjct: 1375 IIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGL 1434

Query: 589  EGPPGTKGNQGPSGPQGPLGYPGPRGVKGV 618
             G PGT+G  GP GP G  G PGP G   V
Sbjct: 1435 PGQPGTRGLDGPPGPDGLQGPPGPPGTSSV 1464



 Score =  101 bits (251), Expect = 7e-21
 Identities = 68/169 (40%), Positives = 81/169 (47%), Gaps = 14/169 (8%)

Query: 1268 GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGP---PGEQGEKGDR 1324
            GQ     A     P       G+ G +G+ G  G +GHPGL G  GP   PG +G+KGD 
Sbjct: 21   GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80

Query: 1325 GLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPP 1384
            G+PGP G  G +G  G+PG  G       PGLPG  G  GA G  G  G  G KG +G P
Sbjct: 81   GIPGPPGPKGIRGPPGLPGFPGT------PGLPGMPGHDGAPGPQGIPGCNGTKGERGFP 134

Query: 1385 GHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTG--GAPGSPG 1431
            G PG PG    P P  +P    +   GS +M      P G  G PG PG
Sbjct: 135  GSPGFPGLQGPPGPPGIP--GMKGEPGSIIMSSLPG-PKGNPGYPGPPG 180


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score =  991 bits (2563), Expect = 0.0
 Identities = 594/1336 (44%), Positives = 675/1336 (50%), Gaps = 206/1336 (15%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 322
            P  Q   GP G+ G KGEP      +++   PGP+G  G  GPPGIQG PGP G PG  G
Sbjct: 140  PGLQGPPGPPGIPGMKGEPG----SIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIG 195

Query: 323  PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPP 382
            PPG  GL G  G PG PG    +   F    G+KG                    L+GPP
Sbjct: 196  PPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKG-----------------EQGLQGPP 238

Query: 383  GPMGYT----------------GRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGK 426
            GP G                  G PG  G PG PG++G  G   P G +G +G  G PGK
Sbjct: 239  GPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGP--PGGEKGEKGEQGEPGK 296

Query: 427  AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPG----PPGEDG 482
               RG+ G DG  G PG PG+ GD G+ G PG  GEKG +GDTG  G PG     PG   
Sbjct: 297  ---RGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGI 353

Query: 483  ERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGE----- 537
              G+ G IG  GLPGE G RG  G +GPPG+PGPPG   M GP GP G  G +G+     
Sbjct: 354  TIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM-GPPGPPGFPGERGQKGDEG 412

Query: 538  ------PGPPGQQGTPGTQGLPGPQGAIGPH-------GEKGPQGKPGLPG--------- 575
                  PGPPG  G PG  GLPGP G  GPH        E GP G PG PG         
Sbjct: 413  PPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQG 472

Query: 576  ----------------MPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVD 619
                            + G  G PG PG  GPPG+ G  G  G +G  G  GP+G+ G+ 
Sbjct: 473  VKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIP 532

Query: 620  GIRGLKGHKGEKGEDG----FPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGD 675
            G  G  G  G KGE G    FPG KGD G  G  G  G+PG  G  G +G  G  GP G+
Sbjct: 533  GAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGE 592

Query: 676  PGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGP 735
            PG     GE+G  G PGLPG PG  GP G  GF G PG  GEKG +G++G  G  G  GP
Sbjct: 593  PGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGP 651

Query: 736  TGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKG---------- 785
             G  GQ   +   GK G  G  G DG  G PG+ GLPG  G  G PG KG          
Sbjct: 652  KGDPGQTITQ--PGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLP 709

Query: 786  -PPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAG----------------- 827
             PPGP G  G+PG PG  G  G  G  GPPGPPG  GP+G  G                 
Sbjct: 710  GPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG 769

Query: 828  ETGPMGERGHPGPPGPPGE---QGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERG 884
              GP G+RG PGPPGPPG     GLPG  G  G  G PGP G PG  G  G++G PG  G
Sbjct: 770  ALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG-IGVQGPPGPPG 828

Query: 885  LPGTAGGPGLKGNEGPSGPPGPAG-----SPGERGAAGSGGPIGPPGRPGPQGPPGAAGE 939
            +PG  G PGL G  G  G PGP G      PGERG+ G  G  GP G PG  G PG AG 
Sbjct: 829  IPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGA 888

Query: 940  KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 999
             G PG KG +G  G  G  GP+G+PG +G PG+ G+DG +G+ G PG  G KG+KGE G 
Sbjct: 889  SGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGL 948

Query: 1000 PGPPGPIGP-----VGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNG------PPGPI 1048
            PGPPGP+ P      G+ G  G  G PG  GP+G+ G  GD G  G +G      PPGP 
Sbjct: 949  PGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPK 1008

Query: 1049 GLQGLPGPSG---EKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG----------- 1094
            G  GLPG  G     G  G +G MG PGP G  GP GP+G  G  G PG           
Sbjct: 1009 GNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDP 1068

Query: 1095 GVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERG---------EKGESGQPGEPGPPG 1145
            G+ ++G PG  G  GE G PG  G PG+KG  G+ G          KG+ G PG PG PG
Sbjct: 1069 GISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPG 1128

Query: 1146 PKGPTGDDGPKGNPG------PVG---FPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG 1196
            P GP G  GP GNPG      PVG    PG PGPPGE G  GQDG  G  G+ GEPGQPG
Sbjct: 1129 PPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG 1188

Query: 1197 SPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAG------ 1250
               P G  G PG  G++G  G PG  G  G  G KG+PG  G PG  GP GP G      
Sbjct: 1189 FGNP-GPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPAL 1247

Query: 1251 --PAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGL 1308
              P G PGP G  G PG  G +G PG  G  G  G  G PG PGL G  G KG++G PGL
Sbjct: 1248 EGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL 1307

Query: 1309 IGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGP------IGPGGPPGLPGPAGP 1362
             G  G PG  G KGD GLPG  G PG KG  G+PG++GP      IGP GPPGLPGP+G 
Sbjct: 1308 QGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQ 1367

Query: 1363 K-------GAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLM 1415
                    G  G  G  G KG  G QGP G PGP G    P    +P       DG+   
Sbjct: 1368 SIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP-----GFDGAGGR 1422

Query: 1416 QEDEAIPTGGAPGSPG 1431
            + D  +P  G PG+ G
Sbjct: 1423 KGDPGLP--GQPGTRG 1436



 Score =  879 bits (2272), Expect = 0.0
 Identities = 547/1242 (44%), Positives = 627/1242 (50%), Gaps = 160/1242 (12%)

Query: 237  QNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGP 296
            + +Q  +    P  Q S   RP + E Q     G +GL G++G P    PG  + GPPGP
Sbjct: 229  KGEQGLQGPPGPPGQISEQKRPIDVEFQK----GDQGLPGDRGPPG--PPG--IRGPPGP 280

Query: 297  EGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--G 354
              P G  G  G QG PG  G PG+ G  G+ G+PG  G PG PG     P R G  G  G
Sbjct: 281  --PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGE----PGRDGEKGQKG 334

Query: 355  DKGP-----VVAAQEAQAQAILQQARLAL---------RGPPGPMGYTGRPGP-----LG 395
            D GP     +V  +      I ++  + L         RG PG  G  G PGP     +G
Sbjct: 335  DTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMG 394

Query: 396  QPGSPGLKGESGDLGPQGPRG-----PQGLTGPPGKAGRRGRAGADGAR----------G 440
             PG PG  GE G  G +GP G     P GL G PG  G  G  G  G            G
Sbjct: 395  PPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPG 454

Query: 441  MPGDPGVKGDRGFDGLPGLPGEKGHR----------GDTGAQGLPGPPGEDGERGDDGEI 490
             PG PG  GD+G  G  G+ G+KG            G  G  GLPG PG  G  G  G+ 
Sbjct: 455  PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQK 514

Query: 491  GPRGLPGESGPRGLLGPKGPPGIPGPPGVRG-------MDGPQGPKGSLGPQGEPGPPGQ 543
            G +G  G +GP+GL G  G PG PG PG +G         G +G KG LG  G PG PG 
Sbjct: 515  GEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGL 574

Query: 544  QGTPGTQGLPGPQGAIGP------HGEKGPQGKPGLPGMPGSDGPPGHPG--KEGPPGTK 595
             GTPG  GLPG  G  G        GE+GP G PGLPG+PG+ GP G PG    GP G K
Sbjct: 575  PGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEK 634

Query: 596  GNQGPSGPQGPLGYPGPRGVKGVDGIR-GLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV 654
            G QG +G  G  G PGP+G  G    + G  G  G  G DG  G  GD G+ G  G  G+
Sbjct: 635  GIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGI 694

Query: 655  PGSRGEDG--------PEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQG----- 701
            PGS+GE G        P GPKG  G  G PG PG  G  G  G PG PG+PG +G     
Sbjct: 695  PGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFA 754

Query: 702  ---PKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSG 758
               P G  G PGF GA G KG RG  G  GP G  G  G  G +G  G  G+ G  G  G
Sbjct: 755  LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPG 814

Query: 759  --GDGPHGPPGERGLPGPQGP---NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGP 813
              G G  GPPG  G+PGP G    +G PG KG PGPPG D +PG PG+RG  G  G  GP
Sbjct: 815  LPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLD-VPGPPGERGSPGIPGAPGP 873

Query: 814  ---PGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGK 870
               PG PG+ G  GA+G  G  GE G  GPPGPPG  G+PG +G  G KGD G  G PG 
Sbjct: 874  IGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGL 933

Query: 871  DGPAGLRGFPGERGLPGTAG--GPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP 928
             GP G +G  GE GLPG  G   P L G++G  G PG  G PG  G  G  G  G PG+P
Sbjct: 934  PGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQP 993

Query: 929  GPQG------PPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAG---PPGVAGEDGDK 979
            G  G      PPG  G  G+PG+ G IGP G  G  G +G PGP G   PPG +G  G  
Sbjct: 994  GLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQP 1053

Query: 980  GEVGDPGQKGTKGNKGEH--------GPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFG 1031
            G  G PGQKG KG+ G          GP G PG  G  G PG  G+ G+PG  G  G  G
Sbjct: 1054 GSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPG 1113

Query: 1032 AKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMG------PPGPPGPRGPAGPNG 1085
            AKG  G  GF G PGP G +G+ GP G  G  G+ GP+G       PGPPG +G  G +G
Sbjct: 1114 AKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDG 1173

Query: 1086 ADGPQGPPG-----GVGNLGPPGE---KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQ 1137
              GP G  G     G GN GPPG     G+ G+ G PGI G PG+ GP+GE G  G  G 
Sbjct: 1174 IPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGV 1233

Query: 1138 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRG---QDGAKGDRGEDGEPGQ 1194
             G PGPPG  GP  + GPKGNPGP G PG PG PG  GP G     G KG++G  G+PG 
Sbjct: 1234 QGPPGPPGSPGPALE-GPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGL 1292

Query: 1195 PGSPGPTGENGPPGPLGK---------RGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGP 1245
            PG PG  G+ GPPG  G          +G  G PG  G  G KG  G PG+ G  G+ G 
Sbjct: 1293 PGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGL 1352

Query: 1246 VGPAGPAGKPGPDGLR----------GLPGSVGQQGRPGATGQAGPPGPVGPPGLP---G 1292
            +GP GP G PGP G            G+PG  G +G PG  G  G PGP GPPG P   G
Sbjct: 1353 IGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNG 1412

Query: 1293 LRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPG 1334
            L G  GA G KG PGL G  G  G  G  G  GL GP G PG
Sbjct: 1413 LPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1454



 Score =  819 bits (2115), Expect = 0.0
 Identities = 491/1070 (45%), Positives = 556/1070 (51%), Gaps = 115/1070 (10%)

Query: 446  GVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLL 505
            G+KG++G  G PGL   +GH G  G  G  GPPG  G++GDDG      +PG  GP+G+ 
Sbjct: 42   GIKGEKGERGFPGL---EGHPGLPGFPGPEGPPGPRGQKGDDG------IPGPPGPKGIR 92

Query: 506  GPKGPPGIPGPPGVRGM------DGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAI 559
            GP G PG PG PG+ GM       GPQG  G  G +GE G PG  G PG QG PGP G  
Sbjct: 93   GPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIP 152

Query: 560  GPHGE---------KGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYP 610
            G  GE          GP+G PG PG PG  G PG  G  GP G  G  G  GP GP G P
Sbjct: 153  GMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLP 212

Query: 611  GPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIG-------VKGDRGEVGVPGSRGEDGP 663
            GP+G  G++  +G KG KGE+G  G PG  G I        V+  +G+ G+PG R   GP
Sbjct: 213  GPKGNMGLN-FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDR---GP 268

Query: 664  EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 723
             GP G  GP G PG  G  GEKG+ G PG  G PG+ G  G  G PG PG  G  G  G 
Sbjct: 269  PGPPGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326

Query: 724  SGKSGPRGERGPTGPRGQRGPRGATGKS-GAKGTSGGDGPHGPPGERGLPGPQGPNGFPG 782
             G+ G +G+ GP GP G   PR  TG + G KG  G  G  G  GERG PG QGP G PG
Sbjct: 327  DGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPG 386

Query: 783  PKGPP--GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERG---- 836
            P G    GPPG  G PG  GQ+G+ G  G    PGPPG+ G  GA G  GP G  G    
Sbjct: 387  PPGAAVMGPPGPPGFPGERGQKGDEGPPG-ISIPGPPGLDGQPGAPGLPGPPGPAGPHIP 445

Query: 837  ------HPGPPGPPGEQGLPGTAGKEGTKGDPGPPG----APGKDGPAGLRGFPGERGLP 886
                   PGPPGPPG  G  G  G++G KGD G         G  GP G  G PG  G P
Sbjct: 446  PSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPP 505

Query: 887  GTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGP----QGPPGAAGEKGV 942
            G+ G PG KG +G +G  GP G PG  GA G+ G  G  G PG      G  G  GE G 
Sbjct: 506  GSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGS 565

Query: 943  PGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPP-- 1000
            PG  G  G  G  G  G  GLPGP G PG     G++G  G+PG  G  GN G  GPP  
Sbjct: 566  PGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF 625

Query: 1001 GPPGPIGPVGQPGAAGADGEPGARGPQGHFGA-------------KGDEGTRGFNGPPGP 1047
            GPPGP+G  G  G AG  G+PG  GP+G  G               G +G  G  G PG 
Sbjct: 626  GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGL 685

Query: 1048 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1107
             G  GLPG  G KGE G  G +G PGPPGP+G  G  G  G  G PG +G  GPPG  G 
Sbjct: 686  PGQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGF 744

Query: 1108 PGESGSPGI-----QGEPGVKGPRGERGEKGESGQPGEPGPPGP------KGPTGDDGPK 1156
            PG  G PG       G PG+ G +G  G KG+ G PG PGPPG        GP GD GP 
Sbjct: 745  PGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804

Query: 1157 GNPGPVGFP--------GDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG--SPGPTGENGP 1206
            G PGP+G P        G PGPPG  GP GQ G  G  GE G+PG PG   PGP GE G 
Sbjct: 805  GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGS 864

Query: 1207 PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGS 1266
            PG  G  GP G PGS G  G  GA G PG  G  G  GP GP GP G PG  G+ GL G 
Sbjct: 865  PGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924

Query: 1267 VGQQGRPGATGQAGPPGPVGPPGLPGLRGD-----AGAKGEKGHPGLIGLIGPPGEQGEK 1321
             G QG+PG  G  G  G  G PGLPG  G       G+KGEKG PGL G+   PG  G K
Sbjct: 925  DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGI---PGVSGPK 981

Query: 1322 GDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQ 1381
            G +GLPG  G PG  G+ G+PG  GP G  G PG PG  GP G KG  G  G  G +GV+
Sbjct: 982  GYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVE 1041

Query: 1382 GPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1431
            GPPG  G PG+   P            + G +  + D  I + G PG PG
Sbjct: 1042 GPPGPSGVPGQPGSP-----------GLPGQKGDKGDPGISSIGLPGLPG 1080



 Score =  776 bits (2003), Expect = 0.0
 Identities = 459/1017 (45%), Positives = 526/1017 (51%), Gaps = 81/1017 (7%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 322
            P  +   G +G+KG+KG+      G  + GPPG  G  GL GPPG  G PG  G+ G+ G
Sbjct: 462  PGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAG 521

Query: 323  PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKG-----PVVAAQEAQAQAILQQARLA 377
              G  GLPG  GAPG PG        F    G+ G     P +   + +  +        
Sbjct: 522  ATGPKGLPGIPGAPGAPG--------FPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573

Query: 378  LRGPPGPMGYTGRPGPLGQPG------------SPGLKGESGDLGPQGPRGPQGLTGPPG 425
            L G PG  G  G PGP G+PG            +PGL G  G++GP GP G     GPPG
Sbjct: 574  LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG----FGPPG 629

Query: 426  KAGRRGRAGADGARGMPGDPGVKGDRGFD----GLPGLPGEKGHRGDTGAQGLPGPPGED 481
              G +G  G  G  G PG PG KGD G      G PGLPG  G  GD G  G PG PG+ 
Sbjct: 630  PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689

Query: 482  GERGDDGEIGPRG-----LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQG 536
            G  G  G  G  G     LPG  GP+G  G  GPPG PG PG  G++GP GP G  GP+G
Sbjct: 690  GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG 749

Query: 537  EPG-----PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG---PPGHPGK 588
            EPG     PPG  G PG +G  GP+G  G  G  GP G+ GL G+PG  G   P G PG 
Sbjct: 750  EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGP 809

Query: 589  EGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGED--GFPGFKGDIGVK 646
             GPPG  G  G  GP GP G PGP G  G+ GI G KG  G  G D  G PG +G  G+ 
Sbjct: 810  MGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIP 868

Query: 647  GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL 706
            G  G +G PGS G  G  G  G  G  G+ G  G  G  G LG+PG  G PG +G  G  
Sbjct: 869  GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ 928

Query: 707  GFPGFPGASGEKGARGLSGKSGPRGERGPT--GPRGQRGPRGATGKSGAKGTSGGDGPHG 764
            G PG PG +GEKG++G  G  GP G   P   G +G++G  G  G  G  G  G  G  G
Sbjct: 929  GQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPG 988

Query: 765  PPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGF------QGKTGPPGPPG 818
             PG+ GL G  G  G PGPKG PG PG+ GL G PG +G +G       QG  GPPGP G
Sbjct: 989  DPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSG 1048

Query: 819  VVGPQGAAGETGPMGERGHPGP--------PGPPGEQGLPGTAGKEGTKGDPGPPGAPGK 870
            V G  G+ G  G  G++G PG         PGP GE GLPG  G  G KG  G PG PG 
Sbjct: 1049 VPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGL 1108

Query: 871  DGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPG---R 927
             G  G +G PG  G PGT G PG KG  GP G PG  G PG  G  G  G  GPPG   +
Sbjct: 1109 PGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGK 1168

Query: 928  PGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQ 987
            PG  G PG AG+KG PG+ G  G  G  G+ G  G  G  G PG+ G  G  G  G+PG 
Sbjct: 1169 PGQDGIPGPAGQKGEPGQPG-FGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGF 1227

Query: 988  KGTKGNKGEHGPPGPPGPI--GPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP 1045
             G  G +G  GPPG PGP   GP G PG  G  G PG  GP+G  G  G+ G +G  G P
Sbjct: 1228 HGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNP 1287

Query: 1046 GPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEK 1105
            G  GL GLPG    KG+ G  G  G PG PG  G  G  G  G  G PG  G  G PG  
Sbjct: 1288 GQPGLPGLPGL---KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSA 1344

Query: 1106 GEPGESGSPGIQGEPGVKGPRGERGE-KGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGF 1164
            G  GE G  G  G PG+ GP G+    KG++G PG PG PG KG  G  GP+G PGP G 
Sbjct: 1345 GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGP 1404

Query: 1165 PGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGS 1221
            PGDPG  G  G  G  G KGD      PG PG PG  G +GPPGP G +GP G PG+
Sbjct: 1405 PGDPGRNGLPGFDGAGGRKGD------PGLPGQPGTRGLDGPPGPDGLQGPPGPPGT 1455



 Score =  559 bits (1440), Expect = e-159
 Identities = 357/848 (42%), Positives = 405/848 (47%), Gaps = 159/848 (18%)

Query: 736  TGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL 795
            +G +G++G RG  G  G  G  G  GP GPPG RG  G  G  G PGPKG  GPP   GL
Sbjct: 41   SGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPP---GL 97

Query: 796  PGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGK 855
            PG PG  G  G  G  G PGP G+ G  G  GE G  G  G PG  GPPG  G+PG  G+
Sbjct: 98   PGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGE 157

Query: 856  EGT---KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP---PGPAGS 909
             G+      PGP G PG  GP G++G PG  G+PG  G PG  G  GP GP   PGP G+
Sbjct: 158  PGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGN 217

Query: 910  --------PGERGAAGSGGPIGPPGR-------------------PGPQGPPGAAGEKGV 942
                     GE+G  G  GP GPPG+                   PG +GPPG  G +G 
Sbjct: 218  MGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP 277

Query: 943  P----GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHG 998
            P    GEKG  G  G  G +G  G  G  G PG+ G  GD G  G+PG+ G KG KG+ G
Sbjct: 278  PGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTG 337

Query: 999  PPGPPGPI-------------GPVGQPGAAGADGE---------------PGA--RGPQG 1028
            PPGPPG +             G +G PG  G  GE               PGA   GP G
Sbjct: 338  PPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG 397

Query: 1029 HFGAKGDEGTRGFNGP-----PGPIGLQGLPGPSGEKGETGDVGPMGP-------PGPPG 1076
              G  G+ G +G  GP     PGP GL G PG  G  G  G  GP  P       PGPPG
Sbjct: 398  PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG 457

Query: 1077 PRGPAGPNGADGPQGPPG----------GVGNLGPPGEKGEPGESGSPGIQGEPGVKGPR 1126
            P G  G  G  G QG  G          G G  GPPG+ G PG  G PG  G PG KG +
Sbjct: 458  PPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEK 517

Query: 1127 GERGEKGESGQPGEPGPPGP----------------KGPTGDDGPKGNPGPVGFPGDPGP 1170
            G+ G  G  G PG PG PG                  G  GD G  G+PG  G PG PG 
Sbjct: 518  GQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT 577

Query: 1171 PGEG------GPRGQDGA---KGDRGEDGEPGQPGSPGPTGEN-----GPPGPLGKRGPA 1216
            PG+       GP+G+ G    KG+RG  G PG PG PG  G       GPPGP+G++G  
Sbjct: 578  PGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQ 637

Query: 1217 GSPGSEGRQGGKGAKGDPGAI----------GAPGKTGPVGPAGPAGKPGPDGLRGLPGS 1266
            G  G+ G+ G  G KGDPG            G PG+ G VG  G  G PG  GL G+PGS
Sbjct: 638  GVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGS 697

Query: 1267 VGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRG- 1325
             G+ G PG     G PGP GP G PG+ G  GA G  G  GL G  GPPG  G KG+ G 
Sbjct: 698  KGEPGIPG----IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF 753

Query: 1326 -LPGPQGSP---------GQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPK 1375
             LPGP G P         G KG+ G PG  GP G  G  GLPGP G  G  G  GP GP 
Sbjct: 754  ALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPP 813

Query: 1376 GEK--GVQGPPGHPGPPGEVIQP----LPIQM--PKKTRRSVDGSRLMQEDEAIPTG--- 1424
            G    GVQGPPG PG PG + QP    +P +   P      V G    +    IP     
Sbjct: 814  GLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGP 873

Query: 1425 -GAPGSPG 1431
             G PGSPG
Sbjct: 874  IGPPGSPG 881



 Score =  553 bits (1424), Expect = e-157
 Identities = 342/791 (43%), Positives = 388/791 (49%), Gaps = 131/791 (16%)

Query: 262  EPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPG---------IQGNP 312
            +P      G  G+ G KGEP +  PG+ + GPPGP+G  G+ GPPG         ++G P
Sbjct: 682  DPGLPGQPGLPGIPGSKGEPGI--PGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPP 739

Query: 313  GPVGDPGERG--------PPGRAGLPGSDGA---------PGPPGTSLMLPFRFGSGG-- 353
            GP G PG +G        PPG  GLPG  GA         PGPPG     P R G  G  
Sbjct: 740  GPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGP----PGRTGLDGLP 795

Query: 354  GDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQG 413
            G KG V    +           + ++GPPGP G    PGP+GQPG  G+ GE GD GP G
Sbjct: 796  GPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI---PGPIGQPGLHGIPGEKGDPGPPG 852

Query: 414  --------------------PRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG------- 446
                                P GP G  G PGKAG  G  G  G  GM G PG       
Sbjct: 853  LDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGI 912

Query: 447  --------VKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED-----GERGDDGEIGPR 493
                    +KGD G  G PGLPG  G +G  G  GLPGPPG       G +G+ GE G  
Sbjct: 913  PGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLP 972

Query: 494  GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG---PPGQQGTPGTQ 550
            G+PG SGP+G  G  G PG PG  G  G+ GP GPKG+ G  G+PG   PPG +GT G  
Sbjct: 973  GIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDM 1032

Query: 551  GLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYP 610
            G PGPQG  GP G  G  G+PG PG+PG  G  G PG     G  G  GP G  G  GYP
Sbjct: 1033 GFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSI-GLPGLPGPKGEPGLPGYP 1091

Query: 611  GPRGVKGV---DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPK 667
            G  G+KG     G+ GL G  G KG+ G PGF G  G  G +G  G PG+ G  G  GP 
Sbjct: 1092 GNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPV 1151

Query: 668  GRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGF-----PGFPGASGEKGARG 722
            G  G  G PGPPG   EKGK G  G+PG  G++G  G  GF     PG PG SG+KG  G
Sbjct: 1152 GGGGHPGQPGPPG---EKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGG 1208

Query: 723  LSG------KSGPRGERGPTGPRGQRGPRGATGKSGA--KGTSGGDGPHGPPGERGLPGP 774
            L G        GP+GE G  G  G +GP G  G  G   +G  G  GP GPPG  GLPGP
Sbjct: 1209 LPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGP 1268

Query: 775  QGPNGFPGP---------------------KGPPGPPGKDGLPGHPGQRGEVGFQGKTGP 813
            +GP G PG                      KG  GPPG  G PG PG  G  G  G  G 
Sbjct: 1269 EGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGV 1328

Query: 814  PGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQG-------LPGTAGKEGTKGDPGPPG 866
            PG PG+ GP G  G  GP GE G  GPPGPPG  G       + G AG  G  G PG  G
Sbjct: 1329 PGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKG 1388

Query: 867  APGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPG 926
             PG  GP GL   PG  G PG  G  GL G +G  G  G  G PG+ G  G  GP GP G
Sbjct: 1389 LPGPQGPQGL---PGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDG 1445

Query: 927  RPGPQGPPGAA 937
              GP GPPG +
Sbjct: 1446 LQGPPGPPGTS 1456



 Score =  514 bits (1324), Expect = e-145
 Identities = 309/707 (43%), Positives = 352/707 (49%), Gaps = 109/707 (15%)

Query: 789  PPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQG 848
            P  K    G  G++GE GF G  G PG PG  GP+G  G  G  G+ G PGPPGP G +G
Sbjct: 34   PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRG 93

Query: 849  LPGTAGKEGTKGDPGPP---GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPG 905
             PG  G  GT G PG P   GAPG  G  G  G  GERG PG+ G PGL+G  GP G PG
Sbjct: 94   PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPG 153

Query: 906  PAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPG 965
              G PG    +   GP G PG PGP G  G  G  G+PG  GP GP G  G  GP GLPG
Sbjct: 154  MKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPG 213

Query: 966  P--------AGPPGVAGEDGDKGEVGDPG-------------QKGTKGNKGEHGPPGPPG 1004
            P         GP G  GE G +G  G PG             QKG +G  G+ GPPGPPG
Sbjct: 214  PKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273

Query: 1005 PIGPVGQPGA-AGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET 1063
              GP G PG   G  GE G  G +G  G  G+ G  G  G PG  G  G PG  GEKG+ 
Sbjct: 274  IRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQK 333

Query: 1064 GDVGPMGPP-------------------GPPGPRGPAGPNGADGPQGPPG-----GVGNL 1099
            GD GP GPP                   G PG  G  G  G  G QGPPG     G   +
Sbjct: 334  GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM 393

Query: 1100 GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN- 1158
            GPPG  G PGE G  G +G PG+  P    G  G  GQPG PG PGP GP G   P  + 
Sbjct: 394  GPPGPPGFPGERGQKGDEGPPGISIP----GPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449

Query: 1159 ---PGPVGFPGDPGPPGEGGPRGQDGAKGDRGE-------------DGEPGQPGSPGPTG 1202
               PGP   PG PG PG+ G +G+ G KGD+G+              G+PG PG PGP G
Sbjct: 450  ICEPGP---PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPG 506

Query: 1203 ENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPV-------GPAGPAGKP 1255
              G PG  G++G AG+ G +G  G  GA G PG  G+ G+ G +       G  G  G P
Sbjct: 507  SLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSP 566

Query: 1256 GPDGLRGLPGSVGQQGRPGATGQAGPP---------GPVGPPGLPGLRGDAGAK------ 1300
            G  GL GLPG+ GQ G PG  G  G P         GP G PGLPGL G+ G        
Sbjct: 567  GAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFG 626

Query: 1301 -----GEKGHPGLIGLIGPPGEQGEKGD-------RGLPGPQGSPGQKGEMGIPGASGPI 1348
                 GEKG  G+ G  G PG  G KGD        G PG  G+PG+ G++G+PG  G  
Sbjct: 627  PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP 686

Query: 1349 GPGGPPGLPGPAGPKGAK--GATGPGGPKGEKGVQGPPGHPGPPGEV 1393
            G  G PG+PG  G  G    G  GP GPKG  G+ GPPG PG PG +
Sbjct: 687  GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRI 733



 Score =  379 bits (972), Expect = e-104
 Identities = 245/601 (40%), Positives = 277/601 (46%), Gaps = 111/601 (18%)

Query: 270  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 329
            G  G  G KGE  ++ P     GPPGP G  G  G PG++G+ G  G PG  GP G  G 
Sbjct: 887  GASGFPGTKGEMGMMGP----PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGS 942

Query: 330  PGSDGAPGPPGTSLMLPFRFGSGG--------------GDKGPVVAAQEAQAQAILQQAR 375
             G  G PGPPG   M P   GS G              G KG      +     +  Q  
Sbjct: 943  KGEPGLPGPPGP--MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQP- 999

Query: 376  LALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGA 435
              L GPPGP G  G PG  G  G PGLKG  GD+G  GP+G +G  GP G  G+ G  G 
Sbjct: 1000 -GLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGL 1058

Query: 436  DGARGMPGDPGVK--------GDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDD 487
             G +G  GDPG+         G +G  GLPG PG  G +G  G  GLPG PG  G +G  
Sbjct: 1059 PGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQP 1118

Query: 488  GEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV------RGMDGPQGPKGSLGPQGEPGPP 541
            G  G  G PG  GP+G+ GP G PG+PG PG        G  GP G KG  G  G PGP 
Sbjct: 1119 GLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPA 1178

Query: 542  GQQGTPGTQGL--PGPQGAIGPHGEKG---------------PQGKPGLPGMPGSDGPPG 584
            GQ+G PG  G   PGP G  G  G+KG               P+G+PG  G PG  GPPG
Sbjct: 1179 GQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPG 1238

Query: 585  HPGKEGPP--GTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF--- 639
             PG  GP   G KGN GP GP G  G PGP G  G+ G  G+KG KG  G+ G PG    
Sbjct: 1239 PPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1298

Query: 640  KGDIG---------------VKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG------P 678
            KGD G               +KGD G  GVPG  G  GP G  G  GP G+PG      P
Sbjct: 1299 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1358

Query: 679  PGL----------------------MGEKGKLGVPGLPGYPGRQGPKGS---LGFPGFPG 713
            PGL                       G KG  G  G  G PG  GP G     G PGF G
Sbjct: 1359 PGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDG 1418

Query: 714  ASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG-------AKGTSGGDGPHGPP 766
            A G KG  GL G+ G RG  GP GP G +GP G  G S         + +   D P  P 
Sbjct: 1419 AGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQ 1478

Query: 767  G 767
            G
Sbjct: 1479 G 1479



 Score =  285 bits (729), Expect = 3e-76
 Identities = 176/392 (44%), Positives = 207/392 (52%), Gaps = 35/392 (8%)

Query: 248  PQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVL-EPGML-VEGPPGPEGPAGLIGP 305
            P+ +P     P N  P  + + G  GL G  G P    +PG+    G PGP GP G+ GP
Sbjct: 1081 PKGEPGLPGYPGN--PGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGP 1138

Query: 306  PG---IQGNPGPVGD---PGERGPPGRAGLPGSDGAPGPPGTSLMLPFR--FGSGGGDKG 357
            PG   + G PGPVG    PG+ GPPG  G PG DG PGP G     P +  FG+ G    
Sbjct: 1139 PGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGE-PGQPGFGNPGPPGL 1197

Query: 358  PVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPG---PLGQPGSPG--LKGESGDLGPQ 412
            P ++ Q+             L GP G  G+ G PG   P G PGSPG  L+G  G+ GPQ
Sbjct: 1198 PGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ 1257

Query: 413  GPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQ 472
            GP G  GL GP G  G  G  G  G +G PG PG         LPGLPG KG +G  G Q
Sbjct: 1258 GPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPG---------LPGLPGLKGDQGPPGLQ 1308

Query: 473  GLPGPPGEDGERGDDGEIGPRGLPGESGPRGL---LGPKGPPGIPGPPGVRGMDGPQGPK 529
            G PG PG +G +GD G  G  G PG  GP G+    GP+G PG+ GPPG  G+ GP G  
Sbjct: 1309 GNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQ- 1367

Query: 530  GSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKP---GLPGMPGSDGPPGHP 586
             S+  +G+ GPPG  G PG +GLPGPQG  G  G  GP G P   GLPG  G+ G  G P
Sbjct: 1368 -SIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDP 1426

Query: 587  GKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGV 618
            G  G PGT+G  GP GP G  G PGP G   V
Sbjct: 1427 GLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSV 1458


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score =  986 bits (2550), Expect = 0.0
 Identities = 598/1343 (44%), Positives = 677/1343 (50%), Gaps = 217/1343 (16%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 322
            P  Q   GP G+ G KGEP      +++   PGP+G  G  GPPGIQG PGP G PG  G
Sbjct: 140  PGLQGPPGPPGIPGMKGEPG----SIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIG 195

Query: 323  PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPP 382
            PPG  GL G  G PG PG    +   F    G+KG                    L+GPP
Sbjct: 196  PPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKG-----------------EQGLQGPP 238

Query: 383  GPMGYT----------------GRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGK 426
            GP G                  G PG  G PG PG++G  G   P G +G +G  G PGK
Sbjct: 239  GPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGP--PGGEKGEKGEQGEPGK 296

Query: 427  AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPG----PPGEDG 482
               RG+ G DG  G PG PG+ GD G+ G PG  GEKG +GDTG  G PG     PG   
Sbjct: 297  ---RGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGI 353

Query: 483  ERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGE----- 537
              G+ G IG  GLPGE G RG  G +GPPG+PGPPG   M GP GP G  G +G+     
Sbjct: 354  TIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM-GPPGPPGFPGERGQKGDEG 412

Query: 538  ------PGPPGQQGTPGTQGLPGPQGAIGPH-------GEKGPQGKPGLPG--------- 575
                  PGPPG  G PG  GLPGP G  GPH        E GP G PG PG         
Sbjct: 413  PPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQG 472

Query: 576  ----------------MPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVD 619
                            + G  G PG PG  GPPG+ G  G  G +G  G  GP+G+ G+ 
Sbjct: 473  VKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIP 532

Query: 620  GIRGLKGHKGEKGEDG----FPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGD 675
            G  G  G  G KGE G    FPG KGD G  G  G  G+PG  G  G +G  G  GP G+
Sbjct: 533  GAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGE 592

Query: 676  PGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGP 735
            PG     GE+G  G PGLPG PG  GP G  GF G PG  GEKG +G++G  G  G  GP
Sbjct: 593  PGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGP 651

Query: 736  TGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKG---------- 785
             G  GQ   +   GK G  G  G DG  G PG+ GLPG  G  G PG KG          
Sbjct: 652  KGDPGQTITQ--PGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLP 709

Query: 786  -PPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAG----------------- 827
             PPGP G  G+PG PG  G  G  G  GPPGPPG  GP+G  G                 
Sbjct: 710  GPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG 769

Query: 828  ETGPMGERGHPGPPGPPGE---QGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERG 884
              GP G+RG PGPPGPPG     GLPG  G  G  G PGP G PG  G  G++G PG  G
Sbjct: 770  ALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG-IGVQGPPGPPG 828

Query: 885  LPGTAGGPGLKGNEGPSGPPGPAG-----SPGERGAAGSGGPIGPPGRPGPQGPPGAAGE 939
            +PG  G PGL G  G  G PGP G      PGERG+ G  G  GP G PG  G PG AG 
Sbjct: 829  IPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGA 888

Query: 940  KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 999
             G PG KG +G  G  G  GP+G+PG +G PG+ G+DG +G+ G PG  G KG+KGE G 
Sbjct: 889  SGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGL 948

Query: 1000 PGPPGPIGP-----VGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNG------PPGPI 1048
            PGPPGP+ P      G+ G  G  G PG  GP+G+ G  GD G  G +G      PPGP 
Sbjct: 949  PGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPK 1008

Query: 1049 GLQGLPGPSG---EKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG----------- 1094
            G  GLPG  G     G  G +G MG PGP G  GP GP+G  G  G PG           
Sbjct: 1009 GNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDP 1068

Query: 1095 GVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERG---------EKGESGQPGEPGPPG 1145
            G+ ++G PG  G  GE G PG  G PG+KG  G+ G          KG+ G PG PG PG
Sbjct: 1069 GISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPG 1128

Query: 1146 PKGPTGDDGPKGNPG------PVG---FPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG 1196
            P GP G  GP GNPG      PVG    PG PGPPGE G  GQDG  G  G+ GEPGQPG
Sbjct: 1129 PPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG 1188

Query: 1197 SPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG 1256
               P G  G PG  G++G  G PG  G  G  G KG+PG  G PG  GP    GP G PG
Sbjct: 1189 FGNP-GPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGP---PGPPGSPG 1244

Query: 1257 PDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL----- 1311
            P  L G  G+ G QG PG  G  G PGP GPPGLPG  G  G KG  G PGL GL     
Sbjct: 1245 P-ALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKG 1303

Query: 1312 -IGPPGEQGE---------KGDRGLPGPQGSPGQKGEMGIPGASGP------IGPGGPPG 1355
              GPPG QG          KGD GLPG  G PG KG  G+PG++GP      IGP GPPG
Sbjct: 1304 DQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPG 1363

Query: 1356 LPGPAGPK-------GAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRS 1408
            LPGP+G         G  G  G  G KG  G QGP G PGP G    P    +P      
Sbjct: 1364 LPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP-----G 1418

Query: 1409 VDGSRLMQEDEAIPTGGAPGSPG 1431
             DG+   + D  +P  G PG+ G
Sbjct: 1419 FDGAGGRKGDPGLP--GQPGTRG 1439



 Score =  876 bits (2264), Expect = 0.0
 Identities = 545/1244 (43%), Positives = 627/1244 (50%), Gaps = 161/1244 (12%)

Query: 237  QNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGP 296
            + +Q  +    P  Q S   RP + E Q     G +GL G++G P    PG  + GPPGP
Sbjct: 229  KGEQGLQGPPGPPGQISEQKRPIDVEFQK----GDQGLPGDRGPPG--PPG--IRGPPGP 280

Query: 297  EGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--G 354
              P G  G  G QG PG  G PG+ G  G+ G+PG  G PG PG     P R G  G  G
Sbjct: 281  --PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGE----PGRDGEKGQKG 334

Query: 355  DKGP-----VVAAQEAQAQAILQQARLAL---------RGPPGPMGYTGRPGP-----LG 395
            D GP     +V  +      I ++  + L         RG PG  G  G PGP     +G
Sbjct: 335  DTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMG 394

Query: 396  QPGSPGLKGESGDLGPQGPRG-----PQGLTGPPGKAGRRGRAGADGAR----------G 440
             PG PG  GE G  G +GP G     P GL G PG  G  G  G  G            G
Sbjct: 395  PPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPG 454

Query: 441  MPGDPGVKGDRGFDGLPGLPGEKGHR----------GDTGAQGLPGPPGEDGERGDDGEI 490
             PG PG  GD+G  G  G+ G+KG            G  G  GLPG PG  G  G  G+ 
Sbjct: 455  PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQK 514

Query: 491  GPRGLPGESGPRGLLGPKGPPGIPGPPGVRG-------MDGPQGPKGSLGPQGEPGPPGQ 543
            G +G  G +GP+GL G  G PG PG PG +G         G +G KG LG  G PG PG 
Sbjct: 515  GEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGL 574

Query: 544  QGTPGTQGLPGPQGAIGP------HGEKGPQGKPGLPGMPGSDGPPGHPG--KEGPPGTK 595
             GTPG  GLPG  G  G        GE+GP G PGLPG+PG+ GP G PG    GP G K
Sbjct: 575  PGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEK 634

Query: 596  GNQGPSGPQGPLGYPGPRGVKGVDGIR-GLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV 654
            G QG +G  G  G PGP+G  G    + G  G  G  G DG  G  GD G+ G  G  G+
Sbjct: 635  GIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGI 694

Query: 655  PGSRGEDG--------PEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQG----- 701
            PGS+GE G        P GPKG  G  G PG PG  G  G  G PG PG+PG +G     
Sbjct: 695  PGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFA 754

Query: 702  ---PKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSG 758
               P G  G PGF GA G KG RG  G  GP G  G  G  G +G  G  G+ G  G  G
Sbjct: 755  LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPG 814

Query: 759  --GDGPHGPPGERGLPGPQGP---NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGP 813
              G G  GPPG  G+PGP G    +G PG KG PGPPG D +PG PG+RG  G  G  GP
Sbjct: 815  LPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLD-VPGPPGERGSPGIPGAPGP 873

Query: 814  ---PGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGK 870
               PG PG+ G  GA+G  G  GE G  GPPGPPG  G+PG +G  G KGD G  G PG 
Sbjct: 874  IGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGL 933

Query: 871  DGPAGLRGFPGERGLPGTAG--GPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP 928
             GP G +G  GE GLPG  G   P L G++G  G PG  G PG  G  G  G  G PG+P
Sbjct: 934  PGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQP 993

Query: 929  GPQG------PPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAG---PPGVAGEDGDK 979
            G  G      PPG  G  G+PG+ G IGP G  G  G +G PGP G   PPG +G  G  
Sbjct: 994  GLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQP 1053

Query: 980  GEVGDPGQKGTKGNKGEH--------GPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFG 1031
            G  G PGQKG KG+ G          GP G PG  G  G PG  G+ G+PG  G  G  G
Sbjct: 1054 GSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPG 1113

Query: 1032 AKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMG------PPGPPGPRGPAGPNG 1085
            AKG  G  GF G PGP G +G+ GP G  G  G+ GP+G       PGPPG +G  G +G
Sbjct: 1114 AKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDG 1173

Query: 1086 ADGPQGPPG-----GVGNLGPPGE---KGEPGESGSPGIQGEPGVKGPRGE---RGEKGE 1134
              GP G  G     G GN GPPG     G+ G+ G PGI G PG+ GP+GE    G  G 
Sbjct: 1174 IPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGV 1233

Query: 1135 SGQPGEPGPPGP--KGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEP 1192
             G PG PG PGP  +GP G+ GP+G PG  GF G PGP G  G  G  G KG++G  G+P
Sbjct: 1234 QGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQP 1293

Query: 1193 GQPGSPGPTGENGPPGPLGK---------RGPAGSPGSEGRQGGKGAKGDPGAIGAPGKT 1243
            G PG PG  G+ GPPG  G          +G  G PG  G  G KG  G PG+ G  G+ 
Sbjct: 1294 GLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEP 1353

Query: 1244 GPVGPAGPAGKPGPDGLR----------GLPGSVGQQGRPGATGQAGPPGPVGPPGLP-- 1291
            G +GP GP G PGP G            G+PG  G +G PG  G  G PGP GPPG P  
Sbjct: 1354 GLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGR 1413

Query: 1292 -GLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPG 1334
             GL G  GA G KG PGL G  G  G  G  G  GL GP G PG
Sbjct: 1414 NGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1457



 Score =  819 bits (2115), Expect = 0.0
 Identities = 491/1070 (45%), Positives = 556/1070 (51%), Gaps = 115/1070 (10%)

Query: 446  GVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLL 505
            G+KG++G  G PGL   +GH G  G  G  GPPG  G++GDDG      +PG  GP+G+ 
Sbjct: 42   GIKGEKGERGFPGL---EGHPGLPGFPGPEGPPGPRGQKGDDG------IPGPPGPKGIR 92

Query: 506  GPKGPPGIPGPPGVRGM------DGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAI 559
            GP G PG PG PG+ GM       GPQG  G  G +GE G PG  G PG QG PGP G  
Sbjct: 93   GPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIP 152

Query: 560  GPHGE---------KGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYP 610
            G  GE          GP+G PG PG PG  G PG  G  GP G  G  G  GP GP G P
Sbjct: 153  GMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLP 212

Query: 611  GPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIG-------VKGDRGEVGVPGSRGEDGP 663
            GP+G  G++  +G KG KGE+G  G PG  G I        V+  +G+ G+PG R   GP
Sbjct: 213  GPKGNMGLN-FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDR---GP 268

Query: 664  EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 723
             GP G  GP G PG  G  GEKG+ G PG  G PG+ G  G  G PG PG  G  G  G 
Sbjct: 269  PGPPGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326

Query: 724  SGKSGPRGERGPTGPRGQRGPRGATGKS-GAKGTSGGDGPHGPPGERGLPGPQGPNGFPG 782
             G+ G +G+ GP GP G   PR  TG + G KG  G  G  G  GERG PG QGP G PG
Sbjct: 327  DGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPG 386

Query: 783  PKGPP--GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERG---- 836
            P G    GPPG  G PG  GQ+G+ G  G    PGPPG+ G  GA G  GP G  G    
Sbjct: 387  PPGAAVMGPPGPPGFPGERGQKGDEGPPG-ISIPGPPGLDGQPGAPGLPGPPGPAGPHIP 445

Query: 837  ------HPGPPGPPGEQGLPGTAGKEGTKGDPGPPG----APGKDGPAGLRGFPGERGLP 886
                   PGPPGPPG  G  G  G++G KGD G         G  GP G  G PG  G P
Sbjct: 446  PSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPP 505

Query: 887  GTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGP----QGPPGAAGEKGV 942
            G+ G PG KG +G +G  GP G PG  GA G+ G  G  G PG      G  G  GE G 
Sbjct: 506  GSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGS 565

Query: 943  PGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPP-- 1000
            PG  G  G  G  G  G  GLPGP G PG     G++G  G+PG  G  GN G  GPP  
Sbjct: 566  PGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF 625

Query: 1001 GPPGPIGPVGQPGAAGADGEPGARGPQGHFGA-------------KGDEGTRGFNGPPGP 1047
            GPPGP+G  G  G AG  G+PG  GP+G  G               G +G  G  G PG 
Sbjct: 626  GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGL 685

Query: 1048 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1107
             G  GLPG  G KGE G  G +G PGPPGP+G  G  G  G  G PG +G  GPPG  G 
Sbjct: 686  PGQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGF 744

Query: 1108 PGESGSPGI-----QGEPGVKGPRGERGEKGESGQPGEPGPPGP------KGPTGDDGPK 1156
            PG  G PG       G PG+ G +G  G KG+ G PG PGPPG        GP GD GP 
Sbjct: 745  PGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804

Query: 1157 GNPGPVGFP--------GDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG--SPGPTGENGP 1206
            G PGP+G P        G PGPPG  GP GQ G  G  GE G+PG PG   PGP GE G 
Sbjct: 805  GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGS 864

Query: 1207 PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGS 1266
            PG  G  GP G PGS G  G  GA G PG  G  G  GP GP GP G PG  G+ GL G 
Sbjct: 865  PGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924

Query: 1267 VGQQGRPGATGQAGPPGPVGPPGLPGLRGD-----AGAKGEKGHPGLIGLIGPPGEQGEK 1321
             G QG+PG  G  G  G  G PGLPG  G       G+KGEKG PGL G+   PG  G K
Sbjct: 925  DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGI---PGVSGPK 981

Query: 1322 GDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQ 1381
            G +GLPG  G PG  G+ G+PG  GP G  G PG PG  GP G KG  G  G  G +GV+
Sbjct: 982  GYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVE 1041

Query: 1382 GPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1431
            GPPG  G PG+   P            + G +  + D  I + G PG PG
Sbjct: 1042 GPPGPSGVPGQPGSP-----------GLPGQKGDKGDPGISSIGLPGLPG 1080



 Score =  779 bits (2011), Expect = 0.0
 Identities = 462/1033 (44%), Positives = 533/1033 (51%), Gaps = 110/1033 (10%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 322
            P  +   G +G+KG+KG+      G  + GPPG  G  GL GPPG  G PG  G+ G+ G
Sbjct: 462  PGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAG 521

Query: 323  PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKG-----PVVAAQEAQAQAILQQARLA 377
              G  GLPG  GAPG PG        F    G+ G     P +   + +  +        
Sbjct: 522  ATGPKGLPGIPGAPGAPG--------FPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573

Query: 378  LRGPPGPMGYTGRPGPLGQPG------------SPGLKGESGDLGPQGPRGPQGLTGPPG 425
            L G PG  G  G PGP G+PG            +PGL G  G++GP GP G     GPPG
Sbjct: 574  LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG----FGPPG 629

Query: 426  KAGRRGRAGADGARGMPGDPGVKGDRGFD----GLPGLPGEKGHRGDTGAQGLPGPPGED 481
              G +G  G  G  G PG PG KGD G      G PGLPG  G  GD G  G PG PG+ 
Sbjct: 630  PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689

Query: 482  GERGDDGEIGPRG-----LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQG 536
            G  G  G  G  G     LPG  GP+G  G  GPPG PG PG  G++GP GP G  GP+G
Sbjct: 690  GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG 749

Query: 537  EPG-----PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG---PPGHPGK 588
            EPG     PPG  G PG +G  GP+G  G  G  GP G+ GL G+PG  G   P G PG 
Sbjct: 750  EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGP 809

Query: 589  EGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGED--GFPGFKGDIGVK 646
             GPPG  G  G  GP GP G PGP G  G+ GI G KG  G  G D  G PG +G  G+ 
Sbjct: 810  MGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIP 868

Query: 647  GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL 706
            G  G +G PGS G  G  G  G  G  G+ G  G  G  G LG+PG  G PG +G  G  
Sbjct: 869  GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ 928

Query: 707  GFPGFPGASGEKGARGLSGKSGPRGERGPT--GPRGQRGPRGATGKSGAKGTSGGDGPHG 764
            G PG PG +GEKG++G  G  GP G   P   G +G++G  G  G  G  G  G  G  G
Sbjct: 929  GQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPG 988

Query: 765  PPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGF------QGKTGPPGPPG 818
             PG+ GL G  G  G PGPKG PG PG+ GL G PG +G +G       QG  GPPGP G
Sbjct: 989  DPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSG 1048

Query: 819  VVGPQGAAGETGPMGERGHPGP--------PGPPGEQGLPGTAGKEGTKGDPGPPGAPGK 870
            V G  G+ G  G  G++G PG         PGP GE GLPG  G  G KG  G PG PG 
Sbjct: 1049 VPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGL 1108

Query: 871  DGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGP 930
             G  G +G PG  G PGT G PG KG    SGPPG  G PGE G  G GG    PG+PGP
Sbjct: 1109 PGTPGAKGQPGLPGFPGTPGPPGPKGI---SGPPGNPGLPGEPGPVGGGGH---PGQPGP 1162

Query: 931  QGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGT 990
             G  G  G+ G+PG  G  G  G+ G     G PGP G PG++G+ GD G  G PG  G 
Sbjct: 1163 PGEKGKPGQDGIPGPAGQKGEPGQPGF----GNPGPPGLPGLSGQKGDGGLPGIPGNPGL 1218

Query: 991  KGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGL 1050
             G KGE G  G PG  GP G PG+ G    P   GP+G+ G +G  G  GF G PGP G 
Sbjct: 1219 PGPKGEPGFHGFPGVQGPPGPPGSPG----PALEGPKGNPGPQGPPGRPGFQGLPGPEGP 1274

Query: 1051 QGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGE 1110
             GLPG  G KGE G+ G  G PG PG +G          QGPPG  GN G PG  G  G+
Sbjct: 1275 PGLPGNGGIKGEKGNPGQPGLPGLPGLKGD---------QGPPGLQGNPGRPGLNGMKGD 1325

Query: 1111 SGSPGIQGEPGVKGPRGERGEKGESGQPG---EPGPPGPKGPTG-------DDGPKGNPG 1160
             G PG+ G PG+KGP G  G  G  G+PG    PGPPG  GP+G       D GP G PG
Sbjct: 1326 PGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPG 1385

Query: 1161 ------------PVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPG 1208
                        P G PG  GPPG+ G  G  G  G  G  G+PG PG PG  G +GPPG
Sbjct: 1386 QPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPG 1445

Query: 1209 PLGKRGPAGSPGS 1221
            P G +GP G PG+
Sbjct: 1446 PDGLQGPPGPPGT 1458



 Score =  560 bits (1442), Expect = e-159
 Identities = 351/809 (43%), Positives = 405/809 (50%), Gaps = 125/809 (15%)

Query: 262  EPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPG---------IQGNP 312
            +P      G  G+ G KGEP +  PG+ + GPPGP+G  G+ GPPG         ++G P
Sbjct: 682  DPGLPGQPGLPGIPGSKGEPGI--PGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPP 739

Query: 313  GPVGDPGERG--------PPGRAGLPGSDGA---------PGPPGTSLMLPFRFGSGG-- 353
            GP G PG +G        PPG  GLPG  GA         PGPPG     P R G  G  
Sbjct: 740  GPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGP----PGRTGLDGLP 795

Query: 354  GDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQG 413
            G KG V    +           + ++GPPGP G    PGP+GQPG  G+ GE GD GP G
Sbjct: 796  GPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI---PGPIGQPGLHGIPGEKGDPGPPG 852

Query: 414  --------------------PRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG------- 446
                                P GP G  G PGKAG  G  G  G  GM G PG       
Sbjct: 853  LDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGI 912

Query: 447  --------VKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED-----GERGDDGEIGPR 493
                    +KGD G  G PGLPG  G +G  G  GLPGPPG       G +G+ GE G  
Sbjct: 913  PGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLP 972

Query: 494  GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG---PPGQQGTPGTQ 550
            G+PG SGP+G  G  G PG PG  G  G+ GP GPKG+ G  G+PG   PPG +GT G  
Sbjct: 973  GIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDM 1032

Query: 551  GLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYP 610
            G PGPQG  GP G  G  G+PG PG+PG  G  G PG     G  G  GP G  G  GYP
Sbjct: 1033 GFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSI-GLPGLPGPKGEPGLPGYP 1091

Query: 611  GPRGVKGV---DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPK 667
            G  G+KG     G+ GL G  G KG+ G PGF G  G  G +G  G PG+ G  G  GP 
Sbjct: 1092 GNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPV 1151

Query: 668  GRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGF-----PGFPGASGEKGARG 722
            G  G  G PGPPG   EKGK G  G+PG  G++G  G  GF     PG PG SG+KG  G
Sbjct: 1152 GGGGHPGQPGPPG---EKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGG 1208

Query: 723  LSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGG--DGPHGPPGERGLPGPQGPNGF 780
            L G  G  G  GP G  G  G  G  G  G  G+ G   +GP G PG +G PG  G  G 
Sbjct: 1209 LPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGL 1268

Query: 781  PGPKGPPGPPGKDGLPG---HPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 837
            PGP+GPPG PG  G+ G   +PGQ G  G  G  G  GPPG+ G  G  G  G  G+ G 
Sbjct: 1269 PGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGL 1328

Query: 838  PGPPGPPGEQG---LPGTAGKEGTKGDPGPPGAPGKDGP----------AGLRGFPGERG 884
            PG PG PG +G   +PG+AG EG  G  GPPG PG  GP          AG  G PG+ G
Sbjct: 1329 PGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPG 1388

Query: 885  LPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPG 944
            L G  G  G +G  GP+GPPG  G  G  G  G+GG  G PG PG             PG
Sbjct: 1389 LKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQ------------PG 1436

Query: 945  EKGPIGPTGRDGVQGPVGLPGPAGPPGVA 973
             +G  GP G DG+QGP   PGP G   VA
Sbjct: 1437 TRGLDGPPGPDGLQGP---PGPPGTSSVA 1462



 Score =  559 bits (1440), Expect = e-159
 Identities = 357/848 (42%), Positives = 405/848 (47%), Gaps = 159/848 (18%)

Query: 736  TGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL 795
            +G +G++G RG  G  G  G  G  GP GPPG RG  G  G  G PGPKG  GPP   GL
Sbjct: 41   SGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPP---GL 97

Query: 796  PGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGK 855
            PG PG  G  G  G  G PGP G+ G  G  GE G  G  G PG  GPPG  G+PG  G+
Sbjct: 98   PGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGE 157

Query: 856  EGT---KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP---PGPAGS 909
             G+      PGP G PG  GP G++G PG  G+PG  G PG  G  GP GP   PGP G+
Sbjct: 158  PGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGN 217

Query: 910  --------PGERGAAGSGGPIGPPGR-------------------PGPQGPPGAAGEKGV 942
                     GE+G  G  GP GPPG+                   PG +GPPG  G +G 
Sbjct: 218  MGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP 277

Query: 943  P----GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHG 998
            P    GEKG  G  G  G +G  G  G  G PG+ G  GD G  G+PG+ G KG KG+ G
Sbjct: 278  PGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTG 337

Query: 999  PPGPPGPI-------------GPVGQPGAAGADGE---------------PGA--RGPQG 1028
            PPGPPG +             G +G PG  G  GE               PGA   GP G
Sbjct: 338  PPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG 397

Query: 1029 HFGAKGDEGTRGFNGP-----PGPIGLQGLPGPSGEKGETGDVGPMGP-------PGPPG 1076
              G  G+ G +G  GP     PGP GL G PG  G  G  G  GP  P       PGPPG
Sbjct: 398  PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG 457

Query: 1077 PRGPAGPNGADGPQGPPG----------GVGNLGPPGEKGEPGESGSPGIQGEPGVKGPR 1126
            P G  G  G  G QG  G          G G  GPPG+ G PG  G PG  G PG KG +
Sbjct: 458  PPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEK 517

Query: 1127 GERGEKGESGQPGEPGPPGP----------------KGPTGDDGPKGNPGPVGFPGDPGP 1170
            G+ G  G  G PG PG PG                  G  GD G  G+PG  G PG PG 
Sbjct: 518  GQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT 577

Query: 1171 PGEG------GPRGQDGA---KGDRGEDGEPGQPGSPGPTGEN-----GPPGPLGKRGPA 1216
            PG+       GP+G+ G    KG+RG  G PG PG PG  G       GPPGP+G++G  
Sbjct: 578  PGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQ 637

Query: 1217 GSPGSEGRQGGKGAKGDPGAI----------GAPGKTGPVGPAGPAGKPGPDGLRGLPGS 1266
            G  G+ G+ G  G KGDPG            G PG+ G VG  G  G PG  GL G+PGS
Sbjct: 638  GVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGS 697

Query: 1267 VGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRG- 1325
             G+ G PG     G PGP GP G PG+ G  GA G  G  GL G  GPPG  G KG+ G 
Sbjct: 698  KGEPGIPG----IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF 753

Query: 1326 -LPGPQGSP---------GQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPK 1375
             LPGP G P         G KG+ G PG  GP G  G  GLPGP G  G  G  GP GP 
Sbjct: 754  ALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPP 813

Query: 1376 GEK--GVQGPPGHPGPPGEVIQP----LPIQM--PKKTRRSVDGSRLMQEDEAIPTG--- 1424
            G    GVQGPPG PG PG + QP    +P +   P      V G    +    IP     
Sbjct: 814  GLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGP 873

Query: 1425 -GAPGSPG 1431
             G PGSPG
Sbjct: 874  IGPPGSPG 881



 Score =  514 bits (1324), Expect = e-145
 Identities = 309/707 (43%), Positives = 352/707 (49%), Gaps = 109/707 (15%)

Query: 789  PPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQG 848
            P  K    G  G++GE GF G  G PG PG  GP+G  G  G  G+ G PGPPGP G +G
Sbjct: 34   PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRG 93

Query: 849  LPGTAGKEGTKGDPGPP---GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPG 905
             PG  G  GT G PG P   GAPG  G  G  G  GERG PG+ G PGL+G  GP G PG
Sbjct: 94   PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPG 153

Query: 906  PAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPG 965
              G PG    +   GP G PG PGP G  G  G  G+PG  GP GP G  G  GP GLPG
Sbjct: 154  MKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPG 213

Query: 966  P--------AGPPGVAGEDGDKGEVGDPG-------------QKGTKGNKGEHGPPGPPG 1004
            P         GP G  GE G +G  G PG             QKG +G  G+ GPPGPPG
Sbjct: 214  PKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273

Query: 1005 PIGPVGQPGA-AGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET 1063
              GP G PG   G  GE G  G +G  G  G+ G  G  G PG  G  G PG  GEKG+ 
Sbjct: 274  IRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQK 333

Query: 1064 GDVGPMGPP-------------------GPPGPRGPAGPNGADGPQGPPG-----GVGNL 1099
            GD GP GPP                   G PG  G  G  G  G QGPPG     G   +
Sbjct: 334  GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM 393

Query: 1100 GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN- 1158
            GPPG  G PGE G  G +G PG+  P    G  G  GQPG PG PGP GP G   P  + 
Sbjct: 394  GPPGPPGFPGERGQKGDEGPPGISIP----GPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449

Query: 1159 ---PGPVGFPGDPGPPGEGGPRGQDGAKGDRGE-------------DGEPGQPGSPGPTG 1202
               PGP   PG PG PG+ G +G+ G KGD+G+              G+PG PG PGP G
Sbjct: 450  ICEPGP---PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPG 506

Query: 1203 ENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPV-------GPAGPAGKP 1255
              G PG  G++G AG+ G +G  G  GA G PG  G+ G+ G +       G  G  G P
Sbjct: 507  SLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSP 566

Query: 1256 GPDGLRGLPGSVGQQGRPGATGQAGPP---------GPVGPPGLPGLRGDAGAK------ 1300
            G  GL GLPG+ GQ G PG  G  G P         GP G PGLPGL G+ G        
Sbjct: 567  GAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFG 626

Query: 1301 -----GEKGHPGLIGLIGPPGEQGEKGD-------RGLPGPQGSPGQKGEMGIPGASGPI 1348
                 GEKG  G+ G  G PG  G KGD        G PG  G+PG+ G++G+PG  G  
Sbjct: 627  PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP 686

Query: 1349 GPGGPPGLPGPAGPKGAK--GATGPGGPKGEKGVQGPPGHPGPPGEV 1393
            G  G PG+PG  G  G    G  GP GPKG  G+ GPPG PG PG +
Sbjct: 687  GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRI 733



 Score =  377 bits (968), Expect = e-104
 Identities = 244/604 (40%), Positives = 279/604 (46%), Gaps = 114/604 (18%)

Query: 270  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 329
            G  G  G KGE  ++ P     GPPGP G  G  G PG++G+ G  G PG  GP G  G 
Sbjct: 887  GASGFPGTKGEMGMMGP----PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGS 942

Query: 330  PGSDGAPGPPGTSLMLPFRFGSGG--------------GDKGPVVAAQEAQAQAILQQAR 375
             G  G PGPPG   M P   GS G              G KG      +     +  Q  
Sbjct: 943  KGEPGLPGPPGP--MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQP- 999

Query: 376  LALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGA 435
              L GPPGP G  G PG  G  G PGLKG  GD+G  GP+G +G  GP G  G+ G  G 
Sbjct: 1000 -GLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGL 1058

Query: 436  DGARGMPGDPGVK--------GDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDD 487
             G +G  GDPG+         G +G  GLPG PG  G +G  G  GLPG PG  G +G  
Sbjct: 1059 PGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQP 1118

Query: 488  GEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV------RGMDGPQGPKGSLGPQGEPGPP 541
            G  G  G PG  GP+G+ GP G PG+PG PG        G  GP G KG  G  G PGP 
Sbjct: 1119 GLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPA 1178

Query: 542  GQQGTPG-----------------------------TQGLPGPQGAIGPHGEKGPQGKPG 572
            GQ+G PG                               GLPGP+G  G HG  G QG PG
Sbjct: 1179 GQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPG 1238

Query: 573  LPGMPGS--DGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKG---------VDGI 621
             PG PG   +GP G+PG +GPPG  G QG  GP+GP G PG  G+KG         + G+
Sbjct: 1239 PPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGL 1298

Query: 622  RGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG---- 677
             GLKG +G  G  G PG  G  G+KGD G  GVPG  G  GP G  G  GP G+PG    
Sbjct: 1299 PGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGP 1358

Query: 678  --PPGL----------------------MGEKGKLGVPGLPGYPGRQGPKGS---LGFPG 710
              PPGL                       G KG  G  G  G PG  GP G     G PG
Sbjct: 1359 PGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPG 1418

Query: 711  FPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG-------AKGTSGGDGPH 763
            F GA G KG  GL G+ G RG  GP GP G +GP G  G S         + +   D P 
Sbjct: 1419 FDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQ 1478

Query: 764  GPPG 767
             P G
Sbjct: 1479 CPQG 1482



 Score =  287 bits (734), Expect = 7e-77
 Identities = 174/390 (44%), Positives = 213/390 (54%), Gaps = 28/390 (7%)

Query: 248  PQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVL-EPGML-VEGPPGPEGPAGLIGP 305
            P+ +P     P N  P  + + G  GL G  G P    +PG+    G PGP GP G+ GP
Sbjct: 1081 PKGEPGLPGYPGN--PGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGP 1138

Query: 306  PG---IQGNPGPVGD---PGERGPPGRAGLPGSDGAPGPPGTSLMLPFR--FGSGGGDKG 357
            PG   + G PGPVG    PG+ GPPG  G PG DG PGP G     P +  FG+ G    
Sbjct: 1139 PGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGE-PGQPGFGNPGPPGL 1197

Query: 358  PVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGP 417
            P ++ Q+             L GP G  G+ G PG  G PG PG  G + + GP+G  GP
Sbjct: 1198 PGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALE-GPKGNPGP 1256

Query: 418  QGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDG---LPGLPGEKGHRGDTGAQGL 474
            QG   PPG+ G +G  G +G  G+PG+ G+KG++G  G   LPGLPG KG +G  G QG 
Sbjct: 1257 QG---PPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGN 1313

Query: 475  PGPPGEDGERGDDGEIGPRGLPGESGPRGL---LGPKGPPGIPGPPGVRGMDGPQGPKGS 531
            PG PG +G +GD G  G  G PG  GP G+    GP+G PG+ GPPG  G+ GP G   S
Sbjct: 1314 PGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQ--S 1371

Query: 532  LGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKP---GLPGMPGSDGPPGHPGK 588
            +  +G+ GPPG  G PG +GLPGPQG  G  G  GP G P   GLPG  G+ G  G PG 
Sbjct: 1372 IIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGL 1431

Query: 589  EGPPGTKGNQGPSGPQGPLGYPGPRGVKGV 618
             G PGT+G  GP GP G  G PGP G   V
Sbjct: 1432 PGQPGTRGLDGPPGPDGLQGPPGPPGTSSV 1461



 Score =  101 bits (251), Expect = 7e-21
 Identities = 68/169 (40%), Positives = 81/169 (47%), Gaps = 14/169 (8%)

Query: 1268 GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGP---PGEQGEKGDR 1324
            GQ     A     P       G+ G +G+ G  G +GHPGL G  GP   PG +G+KGD 
Sbjct: 21   GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80

Query: 1325 GLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPP 1384
            G+PGP G  G +G  G+PG  G       PGLPG  G  GA G  G  G  G KG +G P
Sbjct: 81   GIPGPPGPKGIRGPPGLPGFPGT------PGLPGMPGHDGAPGPQGIPGCNGTKGERGFP 134

Query: 1385 GHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTG--GAPGSPG 1431
            G PG PG    P P  +P    +   GS +M      P G  G PG PG
Sbjct: 135  GSPGFPGLQGPPGPPGIP--GMKGEPGSIIMSSLPG-PKGNPGYPGPPG 180


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score =  943 bits (2437), Expect = 0.0
 Identities = 559/1301 (42%), Positives = 677/1301 (52%), Gaps = 113/1301 (8%)

Query: 378  LRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADG 437
            L GPPGP G  G PGP      PGL G  G  G +GPRGP G  G PG            
Sbjct: 623  LMGPPGPKGDCGLPGP------PGLPGLPGIPGARGPRGPPGPYGNPG------------ 664

Query: 438  ARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPG 497
               +PG PG KG +G  GL       G +GD G  GL G PG  G +G  G  GP G PG
Sbjct: 665  ---LPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPG 721

Query: 498  ESGPRGLLGPKGPPGIPGPPGVRGMDGP---QGPKGSLGPQGEPGPPGQQGTPGTQGLPG 554
            E G  G   P+G PG  G PG +G+ GP    GPKGS G  G PG  G  G+ G +GLPG
Sbjct: 722  EQGQPG---PEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPG 778

Query: 555  PQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRG 614
              G  G  G  G  G  G  G PG DG PG  G  GPPG  G  G  G  GP+GYPGP+G
Sbjct: 779  VPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKG 838

Query: 615  VKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTG 674
            +KG+ G  G  G KG+KGE G PG  GD G +GD+G  G+PG              G  G
Sbjct: 839  MKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGF------------PGARG 886

Query: 675  DPGPPGLMGEKGKLGVPGLP---GYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG 731
             PGP G +G+KG +G PG P   G+PG  GP G  G  G  G  G +G  G  G+ GP G
Sbjct: 887  KPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEG 946

Query: 732  ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGF---------PG 782
            + GP GP G  G  G  G+ G  G  G DG  G PG+ G PGP G  GF         PG
Sbjct: 947  DEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPG 1006

Query: 783  PKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPG 842
              G  G  G  G PG PG +G +G  G  G  G PG  GPQG  G  GP G RG  G  G
Sbjct: 1007 IVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRG 1066

Query: 843  PPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSG 902
            P G  G  G  G  G KG PGP G PG+ G    +G  GERG  G+ G PG+ G   PSG
Sbjct: 1067 PRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQ---QGVAGERGHLGSRGFPGIPG---PSG 1120

Query: 903  PPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGE---KGPIGPTGRDGVQG 959
            PPG  G PGE G  G  GPIGPPG  GP+GPPGA GE G+PGE   KG +GP G  G QG
Sbjct: 1121 PPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQG 1180

Query: 960  PVGL---PGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG 1016
             +G    PG  G  G  G DG KG+ GDPG  G  G KG+ G  G  GP GP G  G  G
Sbjct: 1181 LIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRG 1240

Query: 1017 ADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPG 1076
             +G+ G +G +G  GAK   G +G+ G  G +G+ G PGP G  G  G  G +GP G PG
Sbjct: 1241 PEGKSGKQGEKGRTGAK---GAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPG 1297

Query: 1077 PRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPG-IQGEPGVKGPRGERGEKGES 1135
              G  G  G  G  G  G VG LGPPG KGE GE G  G  +G PG  G RG  G++G+ 
Sbjct: 1298 RMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDR 1357

Query: 1136 GQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQP 1195
            G+PG+PG PG +G     G +G PG  G PG PGP G  GP+G  GA+G +G+ G+ G P
Sbjct: 1358 GEPGDPGYPGQEGV---QGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAP 1414

Query: 1196 GSPGPTGENGPPGPLGK---------RGPAGSPGSE---GRQGGKGAKGDPGAIGAPGKT 1243
            G  G  G  G PGP G           GP G PG +   G+QG +G  GDPG +G  GK 
Sbjct: 1415 GRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKR 1474

Query: 1244 GPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEK 1303
            G  G AG  G  GP G +G  G  GQ G PG  G  G  G  G  G PG +G  G  GE 
Sbjct: 1475 GNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEM 1534

Query: 1304 GHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPK 1363
            G PG+ GL GP G  G+ G +G+ GP+G PG  G+ GI    GP+G  GP GLPGP G K
Sbjct: 1535 GFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGI---VGPLGILGPSGLPGPKGDK 1591

Query: 1364 GAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPT 1423
            G++G  G  GP+G  G +G PG PGPPG  IQ     +    +  +D S  ++ +     
Sbjct: 1592 GSRGDWGLQGPRGPPGPRGRPGPPGPPGGPIQLQQDDLGAAFQTWMDTSGALRPESYSYP 1651

Query: 1424 GGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDP 1483
                   GG  EIF +L  L   I+ ++ P GT+++PAR C+DL  C  ++ DG YWVDP
Sbjct: 1652 DRLVLDQGG--EIFKTLHYLSNLIQSIKTPLGTKENPARVCRDLMDCEQKMVDGTYWVDP 1709

Query: 1484 NQGCARDAFRVFCNFTAGGETCVTP-RDDVTQFSYVDSEGSPVGVVQLTFLRLLSVSAHQ 1542
            N GC+ D   V CNFT GG+TC+ P      +F+        +  VQ+ FL LLS    Q
Sbjct: 1710 NLGCSSDTIEVSCNFTHGGQTCLKPITASKVEFA--------ISRVQMNFLHLLSSEVTQ 1761

Query: 1543 DVSYPCSGAA--RDG--------PLRLRGANED--ELSPETSPYVKEFRDGCQTQQGR-- 1588
             ++  C      ++G         +R R  N    E   +  P V    DGC+ Q GR  
Sbjct: 1762 HITIHCLNMTVWQEGTGQTPAKQAVRFRAWNGQIFEAGGQFRPEVS--MDGCKVQDGRWH 1819

Query: 1589 -TVLEVRTPVLEQLPVLDASFSDLGAPPRRGGVLLGPVCFM 1628
             T+   RT   +QLP++        +  ++  + +GP CF+
Sbjct: 1820 QTLFTFRTQDPQQLPIISVDNLPPASSGKQYRLEVGPACFL 1860



 Score =  711 bits (1835), Expect = 0.0
 Identities = 413/963 (42%), Positives = 497/963 (51%), Gaps = 97/963 (10%)

Query: 270  GPRGLKGEKGEPAVLEPGMLVE---------------GPPGPEGPAGLIGP---PGIQGN 311
            GP G KG+KG+P  L PG   +               GPPG +G  G  GP   PG QG 
Sbjct: 667  GPPGAKGQKGDPG-LSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQ 725

Query: 312  PGPVGDPGERGPPGRAGLPGSDGAPGPPGTS--LMLPFRFGSGGGDKGPVVAAQEAQAQA 369
            PGP G PG +G PGR GLPG  G PGP G+   + LP  FG  G D    +     +   
Sbjct: 726  PGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGK 785

Query: 370  ILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGP------QGPRGPQGLTGP 423
            +       + G  GP G  G PG LG PG PG+ G  GDLG        GP+G +GL G 
Sbjct: 786  MGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGS 845

Query: 424  PGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHR------GDTGAQGLPGP 477
             G+ G +G  G  G  G+ GDPG +GD+G  GLPG PG +G        GD G+ G PGP
Sbjct: 846  VGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGP 905

Query: 478  PGEDGERGD---DGEIGPRGLPGE------SGPRGLLGPKGPPGIPGPPGVRGMDGP--- 525
            PG +G  GD    G+ GP G+ G+       GPRG LGP+G  G  GPPG  G++G    
Sbjct: 906  PGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGR 965

Query: 526  ---------QGPKGSLGPQGEPGPPGQQ---------GTPGTQGLPGPQGAIGPHGEKGP 567
                      G KG  G  G PGP G+Q         G PG  G  G +G +GP G  GP
Sbjct: 966  KGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGP 1025

Query: 568  QGKPGLPGMPGSDGPPGHPGKEGPPGT---------KGNQGPSGPQGPLGYPGPRGVKGV 618
            +G  G PGMPG  G PG PG +GPPG+         KG +GP GP GP G  G RG+KG 
Sbjct: 1026 KGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGP 1085

Query: 619  DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP 678
             G +G  G  G++G  G  G  G  G  G  G  G PG++G  G  GP+G  GP G PG 
Sbjct: 1086 PGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGE 1145

Query: 679  PGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGP 738
             G  G  G +G PGLPG  G +G  G LG PG  G  G++G  GL G SGP G  G  G 
Sbjct: 1146 MGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGD 1205

Query: 739  RGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL--- 795
            RG  GP G  G+ G +G  G DGP GPPG  G+ GP+G +G  G KG  G  G  G    
Sbjct: 1206 RGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQ 1265

Query: 796  ---------PGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGE 846
                     PG PG  G  G +G  GP G PG +G QG  G  G  G +G  GP GPPG 
Sbjct: 1266 LGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGP 1325

Query: 847  QGLPGTAGKEG-TKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLK---GNEGPSG 902
            +G  G  G++G  +G PGPPG  G  G  G RG PG+ G PG  G  GL+   G +G  G
Sbjct: 1326 KGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPG 1385

Query: 903  PPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVG 962
             PGP G PG +G+ G+ GP G  G+ G  G  G  G +G+PG +G +G  G +G+ GP G
Sbjct: 1386 HPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDG 1445

Query: 963  LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPG 1022
            LPG  G  G  GE GD G+ G  G  G +GN G  G PG  GP G  G+ G  G  G PG
Sbjct: 1446 LPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPG 1505

Query: 1023 ARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAG 1082
             RG +G  G  G++G  G  G PG  G  G PG +G  G  G  G +G  G  GPRGP G
Sbjct: 1506 KRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPG 1565

Query: 1083 PNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPG 1142
              G +G  GP G +G  G PG KG+ G  G  G+QG  G  GPR         G+PG PG
Sbjct: 1566 LMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPR---------GRPGPPG 1616

Query: 1143 PPG 1145
            PPG
Sbjct: 1617 PPG 1619



 Score =  602 bits (1551), Expect = e-171
 Identities = 361/841 (42%), Positives = 426/841 (50%), Gaps = 82/841 (9%)

Query: 686  GKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPR 745
            G    P L G PG +G  G  G PG PG  G  GARG  G  GP G  G  GP G +G +
Sbjct: 616  GSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQK 675

Query: 746  GATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEV 805
            G  G S  K   G  G  G PG  G PGP G  G  G  GP G PG+ G PG  G  G  
Sbjct: 676  GDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAK 735

Query: 806  GFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPP 865
            G+ G+ G PGP G  GP+G+ G    +G  G  G PG  GE+GLPG  GK G  G PG P
Sbjct: 736  GYPGRQGLPGPVGDPGPKGSRGY---IGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFP 792

Query: 866  GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP---PGP---------AGSPGER 913
            G  G+ GP GL G PGE GLPG  G PGL G+ G  GP   PGP          G PG +
Sbjct: 793  GVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLK 852

Query: 914  GAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA 973
            G  G  G  G  G PG QG  G+ G  G PG +G  GP G+ G +G +G PGP GP G  
Sbjct: 853  GDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFP 912

Query: 974  GEDGDKGEVGDPGQKGTKGNKGEHGPP---GPPGPIGPVGQPGAAGADGEPGARGPQGHF 1030
            G+ G  G+ G  G KG  G +G  GP    GP G  GP+G PGA G +G+PG +G  G  
Sbjct: 913  GDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRP 972

Query: 1031 GAKGDEGTRGFNGPPGPIGLQGL---------PGPSGEKGETGDVGP------------- 1068
            G  G +G  G  G PGP+G QG          PG  GEKG+ G +GP             
Sbjct: 973  GLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHP 1032

Query: 1069 -----MGPPGPPGPRGP---------------AGPNGADGPQGPPGGVGNLGPPGEKGEP 1108
                 MG PG PGP+GP                GP G DGP G  G  G  GPPG +G P
Sbjct: 1033 GMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRP 1092

Query: 1109 GESGSPGIQGE---------PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP 1159
            G  G  G+ GE         PG+ GP G  G KG  G+PG  GP GP GP G+ GPKG P
Sbjct: 1093 GRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPP 1152

Query: 1160 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1219
            G V   G+PG PGE G +G  G  G  GE G  GQ G PG  G++GP GP G +G  G P
Sbjct: 1153 GAV---GEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDP 1209

Query: 1220 GSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQA 1279
            G +G  G KG +G  G  G PG  G  G  GP GK G  G +G  G+ G +G  G  G+ 
Sbjct: 1210 GPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEM 1269

Query: 1280 GPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEM 1339
            G PG  GPPG PG +G  G+ G  G PG +G  G PG  G  G +G+ GP G PG KGE 
Sbjct: 1270 GVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEK 1329

Query: 1340 GIPGASGPI-GPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1398
            G  G  G   GP GPPG  GP G +G +G  G  G  G++GVQG  G PG  G+   P P
Sbjct: 1330 GEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGP 1389

Query: 1399 IQMP-KKTRRSVDGSRLMQEDEAIPTGGAPGSPG--GLEEIFGSLDSL-REEIEQMRRPT 1454
               P  K  +  +G +  Q        GAPG  G  GL+ + G    + R+ +E +  P 
Sbjct: 1390 RGWPGPKGSKGAEGPKGKQ-----GKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPD 1444

Query: 1455 G 1455
            G
Sbjct: 1445 G 1445



 Score =  553 bits (1424), Expect = e-157
 Identities = 351/833 (42%), Positives = 402/833 (48%), Gaps = 111/833 (13%)

Query: 663  PEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGS--LGFPGFPG-ASGEKG 719
            P  P   + PTG   P G    K             + GPK S     P  PG A+ +  
Sbjct: 521  PAVPTPGSAPTGSKKPIGSEASK-------------KAGPKSSPRKPVPLRPGKAARDVP 567

Query: 720  ARGLSGKSGPRGERGPTGPRGQRGPRGATG-----KSGAKGTSGGDGPHGPPGERGLPGP 774
               L+ +  PR  +    P  Q  P           S  + TS G       G    P  
Sbjct: 568  LSDLTTRPSPRQPQ----PSQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAGSTPFPLL 623

Query: 775  QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMG- 833
             GP G  G  G PGPPG  GLPG PG RG    +G  GP G PG+ GP GA G+ G  G 
Sbjct: 624  MGPPGPKGDCGLPGPPGLPGLPGIPGARGP---RGPPGPYGNPGLPGPPGAKGQKGDPGL 680

Query: 834  -----ERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGT 888
                   G  G  G PG  G PG  G++G KG PGP G PG+ G  G  G PG +G PG 
Sbjct: 681  SPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGR 740

Query: 889  AGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP 948
             G PG  G+ GP G  G  G PG  G  GS G  G PG PG +G  G  G  GV GE+  
Sbjct: 741  QGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGER-- 798

Query: 949  IGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQK------------GTKGNKGE 996
             GP G DG  G +GLPGP G PG+ G+ G  G +G PG K            G KG+KGE
Sbjct: 799  -GPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGE 857

Query: 997  HGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGP 1056
             G PG  G  G  G  G+ G  G PGARG  G  G  GD+G+ GF GPPGP G  G  GP
Sbjct: 858  QGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGP 917

Query: 1057 SGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGI 1116
             G+ G  G  G  G  G PGPRG  GP G +GP GPPG  G  G PG KG PG  G  G+
Sbjct: 918  PGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGV 977

Query: 1117 QGE---PGVKGPRGER---------------GEKGESGQPGEPGPPGPKGPTGDDGPKGN 1158
            +GE   PG  GP GE+               GEKG+ G  G PG PGPKG  G  G  G 
Sbjct: 978  KGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGG 1037

Query: 1159 PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1218
             G  G PG  GPPG  GP G  GAKG RG  G  G  G  G  G  GPPGP G+ G  G 
Sbjct: 1038 MGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQ 1097

Query: 1219 PGSEGRQGGKGAK---------GDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQ 1269
             G  G +G  G++         G PG  G PG+ GP GP GP G PG  G +G PG+VG+
Sbjct: 1098 QGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGE 1157

Query: 1270 QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP 1329
             G PG  G  G  GP+G P      G+ G  G++G PGL G  GP G  G KGDRG PGP
Sbjct: 1158 PGLPGEAGMKGDLGPLGTP------GEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGP 1211

Query: 1330 QGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGP------ 1383
             G  G+KG+ G+ G  GP GP G  G+ GP G  G +G  G  G KG KG QG       
Sbjct: 1212 DGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGV 1271

Query: 1384 PGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTG-----GAPGSPG 1431
            PG PGPPG          PK +R S+            PTG     GA G PG
Sbjct: 1272 PGDPGPPG-------TPGPKGSRGSLG-----------PTGAPGRMGAQGEPG 1306



 Score =  425 bits (1092), Expect = e-118
 Identities = 255/600 (42%), Positives = 305/600 (50%), Gaps = 68/600 (11%)

Query: 252  PSRLHRPQNQEPQSQ-AAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQG 310
            P  +  P    PQ    + GP G++G KG      P    +GP G +G  GL GPPG QG
Sbjct: 1035 PGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGP----DGPAGEQGSRGLKGPPGPQG 1090

Query: 311  NPGPVGDPG---ERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG-----------GDK 356
             PG  G  G   ERG  G  G PG  G  GPPGT   LP   G  G           G K
Sbjct: 1091 RPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTK-GLPGEPGPQGPQGPIGPPGEMGPK 1149

Query: 357  GPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRG 416
            GP  A  E             ++G  GP+G  G  G +GQ G PGL+G+SG +GP G +G
Sbjct: 1150 GPPGAVGEPGLPG-----EAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKG 1204

Query: 417  PQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPG 476
             +G  GP G+ G +G+ G  G  G PG PGV G RG +G  G  GEKG    TGA+G  G
Sbjct: 1205 DRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGR---TGAKGAKG 1261

Query: 477  PPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQG 536
              G+ GE G  G+ GP G PG  G RG LGP G PG  G  G  G+ G  G KG +GP G
Sbjct: 1262 YQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLG 1321

Query: 537  EPGPPGQQGTPG----TQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG----------- 581
             PGP G++G  G     +G PGP G  GP G++G +G+PG PG PG +G           
Sbjct: 1322 PPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQ 1381

Query: 582  -PPGHPGKEG---PPGTKGNQGPSGPQGPLGYPGPRGVKGV------------------- 618
              PGHPG  G   P G+KG +GP G QG  G PG RGV+G+                   
Sbjct: 1382 GQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIA 1441

Query: 619  --DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDP 676
              DG+ G  G  G++GE G  G  G +G  G RG  GV G  G  GP G KG +G  G  
Sbjct: 1442 GPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQL 1501

Query: 677  GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 736
            GPPG  G +G+ G+PG  G PG +G  G  G  GFPG +G  G +G  G  G +G +GP 
Sbjct: 1502 GPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPR 1561

Query: 737  GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLP 796
            GP G  G  G  G  G  G SG  GP G  G RG  G QGP G PGP+G PGPPG  G P
Sbjct: 1562 GPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGP 1621



 Score =  323 bits (829), Expect = 6e-88
 Identities = 283/874 (32%), Positives = 321/874 (36%), Gaps = 226/874 (25%)

Query: 766  PGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGA 825
            P    LP  +GP G   P  P  P      P +P Q   VG  G    P  P  +    A
Sbjct: 277  PALGSLPAGRGPRGTVAPATPTKPQRTS--PTNPHQHMAVG--GPAQTPLLPAKLSASNA 332

Query: 826  AGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG-------------KDG 872
                 P    G    P P   Q        +  K  P  P AP              K  
Sbjct: 333  LDPMLPASVGGSTRTPRPAAAQPSQKITATKIPKSLPTKPSAPSTSIVPIKSPHPTQKTA 392

Query: 873  PAGLRGF---------PGERGLPGTAGGPG---LKGNEGPSGPPGPAGSPGERGAAGSGG 920
            P+              P  R +P     P    ++ N G   PP P+  P     + S  
Sbjct: 393  PSSFTKSALPTQKQVPPTSRPVPARVSRPAEKPIQRNPGMPRPPPPSTRPLPPTTSSSKK 452

Query: 921  PIGPPGR-----------------------------PGPQGPPGAAGEKGVPGEKGPIGP 951
            PI    R                               P   PG+      P    P  P
Sbjct: 453  PIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSPAPTPGSTRSTRPPATMVP--P 510

Query: 952  TGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQ 1011
            T   G   P     PA P   +   G K  +G    K      G    P  P P+    +
Sbjct: 511  T--SGTSTP--RTAPAVPTPGSAPTGSKKPIGSEASK----KAGPKSSPRKPVPL----R 558

Query: 1012 PGAAGAD-------GEPGARGPQ----------------------------GHFGAKGDE 1036
            PG A  D         P  R PQ                              F   G  
Sbjct: 559  PGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAGST 618

Query: 1037 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGP---AGPNGADGPQGPP 1093
                  GPPGP G  GLPGP G  G  G  G  GP GPPGP G     GP GA G +G P
Sbjct: 619  PFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDP 678

Query: 1094 G---GVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK--- 1147
            G   G  + G  G+ G PG SG+PG  G  G KG  G  G  GE GQPG  G PG K   
Sbjct: 679  GLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYP 738

Query: 1148 ------GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQP------ 1195
                  GP GD GPKG+ G +G PG  G PG  G RG  G  G RG+ G PG P      
Sbjct: 739  GRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGER 798

Query: 1196 ------GSPGPTGENGPP------------GPLGKRGP---------------------- 1215
                  G+PG  G  GPP            GP+G  GP                      
Sbjct: 799  GPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQ 858

Query: 1216 -----AGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV--- 1267
                 +G PG +G +G +G  G PGA G PG  G VG  G  G PGP G  G PG +   
Sbjct: 859  GVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPP 918

Query: 1268 ------GQQGRPGATGQAGP---------PGPVGPPGLPGLRGDAGAKGEKGHPGL---- 1308
                  G +G+PGA G  GP          GP+GPPG PGL G  G KG  G PGL    
Sbjct: 919  GDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVK 978

Query: 1309 --------------------IGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPI 1348
                                IGL+G PG  GEKGDRG+ GP G PG KG MG PG  G +
Sbjct: 979  GEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGM 1038

Query: 1349 ------GPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQP-LPIQM 1401
                  GP GPPG  GP G +GAKG  GP GP G  G QG  G  GPPG   +P  P Q 
Sbjct: 1039 GTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQ 1098

Query: 1402 PKKTRRSVDGSR----LMQEDEAIPTGGAPGSPG 1431
                 R   GSR    +        T G PG PG
Sbjct: 1099 GVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPG 1132



 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 34/76 (44%), Positives = 45/76 (59%), Gaps = 4/76 (5%)

Query: 270  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 329
            G +G++G +G P ++    +V GP G  GP+GL GP G +G+ G  G  G RGPPG  G 
Sbjct: 1553 GFKGIQGPRGPPGLMGKEGIV-GPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGR 1611

Query: 330  PGSDGAPGPPGTSLML 345
            PG    PGPPG  + L
Sbjct: 1612 PGP---PGPPGGPIQL 1624


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  931 bits (2407), Expect = 0.0
 Identities = 588/1366 (43%), Positives = 678/1366 (49%), Gaps = 234/1366 (17%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVE----GPPGPEGPAGLIGPPGIQGNPGPVGDP 318
            P  Q   GP G KGEKG+     PG+  +    G  GP GP G IGP G +G PGP+G+ 
Sbjct: 1432 PGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEA 1491

Query: 319  GE------------RGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG-----GDK---GP 358
            GE            RG PG AG PG+ G  GPPG +     R G  G     GD    GP
Sbjct: 1492 GEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPT----GRQGEKGEPGRPGDPAVVGP 1547

Query: 359  VVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPG-----SPGLKGESGDLGP-- 411
             VA  + +   +         GP GP G TG  G  G PG      PG KG+ GD GP  
Sbjct: 1548 AVAGPKGEKGDV---------GPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIG 1598

Query: 412  -QGPRGPQGLTGPPGKAGRRGRAGADGA---RGMPGDPGVKGDRGFDGLPGLPGEKGHRG 467
              G  GP G +GPPG+ G  GR G  G    RG  G+ G KGD G  G PGLPG+ G RG
Sbjct: 1599 LTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERG 1658

Query: 468  DTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPG------------ 515
              GA G+ GP GE G++GD GE G  G PG SGP+G  G  GPPG PG            
Sbjct: 1659 LRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREK 1718

Query: 516  -PPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQG---AIGPHGEKGPQGKP 571
              PG RG +GP+GPKG     G PG PG++G  G +G PGPQG     GP GEKG +G P
Sbjct: 1719 GEPGDRGQEGPRGPKGD---PGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPP 1775

Query: 572  GLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEK 631
            GL G  G DG PG  G  GP G  G  G  G  G    PG RG +G+ G  G  G  G+ 
Sbjct: 1776 GLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDG---LPGLRGEQGLPGPSGPPGLPGKP 1832

Query: 632  GEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVP 691
            GEDG PG  G  G  GD GE G  G +G+ G  G +GR GP G+ G PG++G +G  G+P
Sbjct: 1833 GEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLP 1892

Query: 692  G--------LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSG------------------ 725
            G         PG PG  GPKG  G  G  G  G  G RGL G                  
Sbjct: 1893 GPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIK 1952

Query: 726  ------------------------KSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDG 761
                                    + GP+G+ G  GP G+ GP G  G+ G KG  G  G
Sbjct: 1953 ASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPG 2012

Query: 762  PHGPPG----ERGLPGPQGPNGFPGPKGPPGPPGKDG------LPGHPGQRGEVGF---Q 808
            P GPPG    ERG PGP G  G PG  G PG PG+ G       PG  G+RGE G    Q
Sbjct: 2013 PQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQ 2072

Query: 809  GKTGPPGPPGVVGPQGAAG------ETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP 862
            G+ GPPG PG  GP G  G      E GP G  G  GPPG  G +G PG+ G +G KGD 
Sbjct: 2073 GRDGPPGLPGTPGPPGPPGPKVSVDEPGP-GLSGEQGPPGLKGAKGEPGSNGDQGPKGDR 2131

Query: 863  GPPGAPGKDGPAGLRG------FPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAA 916
            G PG  G  G  G RG       PGERG+ G  G PGL+G  GP GP G  G PG  GA 
Sbjct: 2132 GVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAP 2191

Query: 917  GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGED 976
            G  GP GP G  G +G PG  G  G  G  GP G  G  G  GP GL GP G PG+ G+ 
Sbjct: 2192 GLAGPAGPQGPSGLKGEPGETGPPG-RGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQV 2250

Query: 977  GDKGEVGDPGQKGTKGNKGEHGPPGPPG------PIGPVGQPGAAGADGEPGARGPQGHF 1030
            G+ G+ G PG+ G  G  G+ G PG PG      P+GP G+PG  GA G+     P    
Sbjct: 2251 GETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLP---- 2306

Query: 1031 GAKGDEGTRG-----FNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNG 1085
            GAKG++G  G       G PG  G +GLPGP GEKGE G  G  G PG  G +G  GP G
Sbjct: 2307 GAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKG 2366

Query: 1086 ADGPQGP--PGGVGNLGPPGEKGE---PGESGSPGIQGEPGVKGPRGERGEKGESGQ--- 1137
              G  G   PG  G  GPPG KG+   PG  G+PG+ G PG  GPRGE G+ G SG+   
Sbjct: 2367 FKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGL 2426

Query: 1138 ---PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEG--GPRGQDGAKGDRGEDGEP 1192
               PG  G PGP GP G  G  G PG  G  GD G PG G  GPRG+ G  G RGEDG P
Sbjct: 2427 AGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRP 2486

Query: 1193 GQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKG-------------AKGDPGAIGA 1239
            GQ G   P G  GPPG  G+RG  G  GS G +G KG             AKGD G  G 
Sbjct: 2487 GQEG---PRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGP 2543

Query: 1240 PGKTGPVGPAGPAGKPGPDGLRGLPGS------------VGQQGRPGATGQAGPPGPVGP 1287
             G  G  GP G  G PG  G +G PG             +G QG+PGA G  G PG  G 
Sbjct: 2544 RGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGK 2603

Query: 1288 PGLPGLRGDAG------AKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGI 1341
             G+PG+RG+ G       +G KG  G+ G  G  GE+G+KG+ G PG  G  G KGEMG 
Sbjct: 2604 DGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGE 2663

Query: 1342 PGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPG---------------H 1386
            PG  G  G  G  GL GP G +G  G  GP G +GEKG +G PG                
Sbjct: 2664 PGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGP 2723

Query: 1387 PGPPGEVIQPLPIQMP-KKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1431
            PGPPG V    P  +  +K  R   G R++         GAPG PG
Sbjct: 2724 PGPPGSVGPRGPEGLQGQKGERGPPGERVV---------GAPGVPG 2760



 Score =  922 bits (2384), Expect = 0.0
 Identities = 571/1372 (41%), Positives = 671/1372 (48%), Gaps = 219/1372 (15%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 322
            P+    + P+G KGE GE  +   G +  GPPG  G  G  G PG QG PG     GERG
Sbjct: 1244 PEPCPVYCPKGQKGEPGEMGLR--GQV--GPPGDPGLPGRTGAPGPQGPPGSATAKGERG 1299

Query: 323  PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--------GDKGPVVAAQEAQAQAIL--- 371
             PG  G PGS G  G PGT    P   GS G        G++GP     E  A   +   
Sbjct: 1300 FPGADGRPGSPGRAGNPGTP-GAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGG 1358

Query: 372  -------QQARLALRGPPGPMGYTGRPGPLGQPGSPG--LKGESGDLGPQGPRGPQGLTG 422
                   ++      GPPGP G  G PGP G PG PG  +KG+ GD G +GP GP     
Sbjct: 1359 EGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGI 1418

Query: 423  PPGKAGRRGRAGADGARGMPGDPGVKGDRG--FDGLPGLPGEKGHRGDTGAQGLPGPPGE 480
             PG+ G  G  G+ G +G  G PG KG++G   DG PGLPG+ G  G+ G +G PG  G 
Sbjct: 1419 APGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGP 1478

Query: 481  DGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP 540
             G+RG  G +G  G  GE GP G  G +G PG+ G PG +G +GP GP G  G +GEPG 
Sbjct: 1479 KGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGR 1538

Query: 541  PGQ-----------QGTPGTQGLPGPQGAIGPHGEKGP-----QGKPGLPGMPGSDGP-- 582
            PG            +G  G  G  GP+GA G  GE+GP      G PG  G PG  GP  
Sbjct: 1539 PGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIG 1598

Query: 583  ----PGHPGKEGPPGTKGNQGPSGPQGPL------GYPGPRGVKGVDGIRGLKGHKGEKG 632
                 G PG  GPPG KG+ G  GP GP+      G  G +G +G  G  GL G  GE+G
Sbjct: 1599 LTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERG 1658

Query: 633  EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK-LGVP 691
              G PG +G +G KGD+G+ G  G  G  G  GPKG  G  G PGPPG + + G      
Sbjct: 1659 LRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREK 1718

Query: 692  GLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGE---RGPTGPRGQRGPRGAT 748
            G PG  G++GP+G  G PG PGA GE+G  G  G  GP+G+   RGP G +G RGP G  
Sbjct: 1719 GEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLD 1778

Query: 749  GKSGAKGTSGGDGPHGP---------PGERGLPGPQGPNGFPGPKGPPGPPGK---DGLP 796
            G+SG  G  G  GP GP         PG  GLPG +G  G PGP GPPG PGK   DG P
Sbjct: 1779 GRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKP 1838

Query: 797  GHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGK- 855
            G  G+ GE G  G+ G  G  G  G  G  G  GP GERG PG  GP G  GLPG  G  
Sbjct: 1839 GLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPP 1898

Query: 856  ----EGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAG--------------------- 890
                 G  G  GP G  G+ G  G +G PGERGL G  G                     
Sbjct: 1899 GQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALRE 1958

Query: 891  --------------------GP-GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP- 928
                                GP G  G +GP G  GP G PGERG  G  G  GP G P 
Sbjct: 1959 IVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPG 2018

Query: 929  ------GPQGPPGAAGEKGVP------------------------GEKGPIGPTGRDGVQ 958
                  GP GP G AGE G P                        GEKG  G  GRDG  
Sbjct: 2019 LALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPP 2078

Query: 959  GPVGLPGPAGPPG--VAGED---GDKGEVGDPGQKGTKGNKGEHGPPGP------PGPIG 1007
            G  G PGP GPPG  V+ ++   G  GE G PG KG KG  G +G  GP      PG  G
Sbjct: 2079 GLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKG 2138

Query: 1008 PVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVG 1067
              G+PG  G DG PG  G +G  G +G  G +G  GPPGP+G  G PGP G  G  G  G
Sbjct: 2139 DRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAG 2198

Query: 1068 PMGP------PGPPGP--RGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1119
            P GP      PG  GP  RG  GP GA G  GPPG  G +GP G  G PG+ G  G  G 
Sbjct: 2199 PQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGA 2258

Query: 1120 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPG---------------PVGF 1164
            PG  G  G+ G++G  G PG PG PGP GP G+ GP G PG               P G 
Sbjct: 2259 PGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGL 2318

Query: 1165 PGD-PGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGP--AGSPGS 1221
             GD  G PG  G RG  G +G++GE G  G+PG PG  G+ G PGP G +G    G PGS
Sbjct: 2319 AGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGS 2378

Query: 1222 EGRQGGKGAKGD------PGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGA 1275
             G  G  G KGD      PGA G  G  G  GP G  G+PGP G RGL G  G++G PG 
Sbjct: 2379 PGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGP 2438

Query: 1276 TGQAGPPGPVGPPGLPGLRGD--------AGAKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1327
             G  GPPG VGPPG  GL+GD         G +GE+G PG+ G  G PG++G +G  G P
Sbjct: 2439 LGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPP 2498

Query: 1328 GPQGSPGQKGEMGIPGASGP-------IGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGV 1380
            G +G  G+KG++G  G  G        +GP GP G  G  G +G +G  G  GP+G+ G 
Sbjct: 2499 GSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGD 2558

Query: 1381 QGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP-TGGAPGSPG 1431
             G  G  G PG+           K    + G R +   +  P   G PG PG
Sbjct: 2559 PGDKGSKGEPGD-----------KGSAGLPGLRGLLGPQGQPGAAGIPGDPG 2599



 Score =  808 bits (2086), Expect = 0.0
 Identities = 513/1243 (41%), Positives = 596/1243 (47%), Gaps = 233/1243 (18%)

Query: 270  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGD---PGERGPPGR 326
            GPRG  G +GE     PG+++ G PGP+G  G  GP G+ G  GP GD   PGE+G PGR
Sbjct: 1563 GPRGATGVQGERG--PPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGR 1620

Query: 327  AGLPG---------------SDGAPGPPGTSLMLPFRFGSGG-----GDKGPVVAAQEAQ 366
             G PG                +G PG PG    LP + G  G     G +GPV   ++  
Sbjct: 1621 PGPPGPVGPRGRDGEVGEKGDEGPPGDPG----LPGKAGERGLRGAPGVRGPV--GEKGD 1674

Query: 367  AQAILQQARLALRGPPGPMGYTGRPGPLGQPG-----SPGL--KGESGDLGPQGPRGPQG 419
                 +  R    G  GP G  G PGP G PG      PG   KGE GD G +GPRGP+G
Sbjct: 1675 QGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKG 1734

Query: 420  LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 479
              G PG  G RG  G  G  G  GDPGV+G  G  G  G PG  G  G  G  G  GP G
Sbjct: 1735 DPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSG 1794

Query: 480  EDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV-------------------- 519
             +G  G  G+ G  GLPG  G +GL GP GPPG+PG PG                     
Sbjct: 1795 PNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDG 1854

Query: 520  -------------RGMDGPQGPKGS---LGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHG 563
                          G DGP+G +G+   LGPQG PG PG  G PG QG PG  G  GP G
Sbjct: 1855 RKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPG-QGFPGVPGGTGPKG 1913

Query: 564  EKGPQGKPGLPGMPGSDGPPGHPG------------------------------------ 587
            ++G  G  G  G+PG  G  G PG                                    
Sbjct: 1914 DRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPV 1973

Query: 588  ---KEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKG-EKGEDGFPGFKGDI 643
               + GP G  G QGP G +GP+G+PG RG+KG  G  G +G  G   GE G PG     
Sbjct: 1974 PERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPG---PS 2030

Query: 644  GVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPK 703
            G+ G+ G+ G+PG  G  G  G  GR G  G+ G  G  GE+G+ G PGLPG PG  GP 
Sbjct: 2031 GLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPP 2090

Query: 704  G---SLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGD 760
            G   S+  PG PG SGE+G  GL G  G  G  G  GP+G RG  G  G  G  G  G D
Sbjct: 2091 GPKVSVDEPG-PGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQD 2149

Query: 761  GPHGPPGERGLPGPQGPNGFPGPKGPPGPPG---KDGLPGHPGQRGEVGFQGKTGPPGPP 817
            G  G PGERG+ GP+G  G  GP+GPPGP G     G PG PG  G  G QG +G  G P
Sbjct: 2150 GNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEP 2209

Query: 818  GVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLR 877
            G  GP G  G TGP G  G PGPPGP G  G  G+ G  G  G+ G PGAPG+DG +G  
Sbjct: 2210 GETGPPGR-GLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGK- 2267

Query: 878  GFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGE------------------------- 912
               G+RG PG  G PGL G  GP G PGP G+PG+                         
Sbjct: 2268 --DGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGE 2325

Query: 913  ------RGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKG-----------PIGPTGRD 955
                  RG  G  G  G  GR G  G PG  G+KG PG KG             GP G  
Sbjct: 2326 PGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPP 2385

Query: 956  GVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPG---------PPGPI 1006
            GV+G +GLPG  G PGV G  G  G  G+ GQ G  G +G  GPPG         PPGP 
Sbjct: 2386 GVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPP 2445

Query: 1007 GPVGQPGAAGADGEPG-----ARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKG 1061
            G VG PGA+G  G+ G       GP+G  G  G  G  G  G  GP GL G PG  GE+G
Sbjct: 2446 GSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERG 2505

Query: 1062 ETGDVGP-------------MGPPGPPGPRGPAG---PNGADGPQGPPGGVGNLGPPGEK 1105
            E GDVG              +GPPGP G +G  G   P G DG +GP G  G+ G  G K
Sbjct: 2506 EKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSK 2565

Query: 1106 GEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGP---PGPKGPTGD---------D 1153
            GEPG+ GS G+ G  G+ GP+G+ G  G  G PG PG    PG +G  GD          
Sbjct: 2566 GEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLK 2625

Query: 1154 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1213
            G +G  G  G  G+ G  GE GP G+ G  G +GE GEPG PG  G  G+ G  GP G R
Sbjct: 2626 GERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDR 2685

Query: 1214 GPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG------PDGLRGLPGS- 1266
            G  G PG +G QG KG +G PG  G PG +G  G AGP G PG      P+GL+G  G  
Sbjct: 2686 GFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGER 2745

Query: 1267 -------VGQQGRPGATGQA------GPPGPVGPPGLPGLRGD 1296
                   VG  G PGA G+       GP GP G  G   L  D
Sbjct: 2746 GPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTED 2788



 Score =  752 bits (1942), Expect = 0.0
 Identities = 470/1150 (40%), Positives = 565/1150 (49%), Gaps = 209/1150 (18%)

Query: 229  EGGQRERPQNQQPH--RAQRSPQQQPSRL-----HRPQNQEPQSQAAHGPRGLKGEKGEP 281
            E G+   P +  P   R +  P   P RL        +  EP  +   GPRG KG+ G P
Sbjct: 1680 EDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLP 1739

Query: 282  AVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPG---PVGDPGERGPPG---RAGLPGSDGA 335
                      G PG  G  G  GPPG QG+PG   P G+ G+RGPPG   R+GL G  GA
Sbjct: 1740 ----------GAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGA 1789

Query: 336  PGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLG 395
             GP G +     + G  G D  P +  ++             L GP GP G  G+PG  G
Sbjct: 1790 AGPSGPNGAAG-KAGDPGRDGLPGLRGEQG------------LPGPSGPPGLPGKPGEDG 1836

Query: 396  QPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGR---RGRAGADGARGMPGDPGVKGD-- 450
            +PG  G  GE GD G  G +G +G +G  G+ GR   +G  GA G  G  G PG+ G   
Sbjct: 1837 KPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVG 1896

Query: 451  ---RGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI----------------- 490
               +GF G+PG  G KG RG+TG++G  G PGE G RG+ G +                 
Sbjct: 1897 PPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASAL 1956

Query: 491  ----------------------GPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGP 528
                                  GP+G  GE GP G  GP G PG  G  G RG  GPQGP
Sbjct: 1957 REIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGP 2016

Query: 529  KG-SLGPQGEPGPPGQQGTPGTQGLPG---------------PQGAIGPHGEKGPQGKPG 572
             G +LG +G PGP G  G PG  G+PG                +G  G  GE+G QG+ G
Sbjct: 2017 PGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDG 2076

Query: 573  LPGMPGSDGPPGHPGK-----EGPPGTKGNQGPSGPQGPLGYPG------PRGVKGVDGI 621
             PG+PG+ GPPG PG      E  PG  G QGP G +G  G PG      P+G +GV GI
Sbjct: 2077 PPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGI 2136

Query: 622  RGLKGHKGEKGEDGFPGFKGD---------------------IGVKGDRGEVGVPGSRGE 660
            +G +G  G +G+DG PG  G+                     +G  GD G  G PG  G 
Sbjct: 2137 KGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGP 2196

Query: 661  DGPEGPKGRTGPTGDPGPPG--LMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEK 718
             GP+GP G  G  G+ GPPG  L G  G +G+PG PG  G  GP+GS G PG  G +G+ 
Sbjct: 2197 AGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKP 2256

Query: 719  GARGLSGKSGPRGERG------------PTGPRGQRGPRGATGKS-----GAKGTSG--- 758
            GA G  G SG  G+RG            P GP+G+ GP GA G++     GAKG  G   
Sbjct: 2257 GAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPG 2316

Query: 759  ---GD--GPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRG-----EVGFQ 808
               GD  G  G  G+RGLPGP+G  G  G  G PG PG+DG  G PG +G      VG  
Sbjct: 2317 GLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVP 2376

Query: 809  GKTGPPGPPGVVGP---------QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTK 859
            G  GPPGPPGV G           G  G  G  G RG  G PGP GE+GL G  G+EG  
Sbjct: 2377 GSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIP 2436

Query: 860  GDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSG 919
            G  GPPG PG  GP G  G  G++G PG     GL G  G  G PG  G  G  G  G  
Sbjct: 2437 GPLGPPGPPGSVGPPGASGLKGDKGDPGV----GLPGPRGERGEPGIRGEDGRPGQEGPR 2492

Query: 920  GPIGPPGRPGPQGPPGAAGEKGVPGEKGP----IGPTGRDGVQGPVGLPGPAGPPGVAGE 975
            G  GPPG  G +G  G  G  G+ G+KG     +GP G  G +G +G  GP G  G  G 
Sbjct: 2493 GLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGP 2552

Query: 976  DGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGD 1035
             GD G+ GD G KG  G+KG  G PG  G +GP GQPGAAG  G+PG+ G  G  G +G+
Sbjct: 2553 RGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGE 2612

Query: 1036 EGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGG 1095
            +G  GF GP G  G +G+ G  G  GE GD G  GPPG PG        G  G  G PG 
Sbjct: 2613 KGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLA------GHKGEMGEPGV 2666

Query: 1096 VGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGP 1155
             G  G PG++G  G  G  G  G+P   GP+G++GEKGE G PG  G PGP G  G  GP
Sbjct: 2667 PGQSGAPGKEGLIGPKGDRGFDGQP---GPKGDQGEKGERGTPGIGGFPGPSGNDGSAGP 2723

Query: 1156 KGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQ--------PGSPGPTGENGPP 1207
                        PGPPG  GPRG +G +G +GE G PG+        PG+PG  GE G P
Sbjct: 2724 ------------PGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRP 2771

Query: 1208 GPLGKRGPAG 1217
            GP G RG  G
Sbjct: 2772 GPAGPRGEKG 2781



 Score =  507 bits (1306), Expect = e-143
 Identities = 317/738 (42%), Positives = 368/738 (49%), Gaps = 107/738 (14%)

Query: 814  PGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGP 873
            P P  V  P+G  GE G MG RG  GPPG PG   LPG  G  G +G PG   A G+ G 
Sbjct: 1244 PEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPG---LPGRTGAPGPQGPPGSATAKGERGF 1300

Query: 874  AGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP 933
             G  G PG  G  G  G PG  G +G  G PGP G PGERG      P GP G PG  G 
Sbjct: 1301 PGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERG------PRGPKGEPGAPGQ 1354

Query: 934  PGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE--DGDKGEVGDPGQKG-- 989
                   G+PG KG  GP+G  G +GP+G PGP GPPG+ G    GDKG+ G+ G  G  
Sbjct: 1355 VIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPG 1414

Query: 990  ----TKGNKGEHGPPGPPGPIGPVGQPGAAG--ADGEPGARGPQGHFGAKGDEGTRGFNG 1043
                  G  G  G PG PGP GPVG PG  G   D E GA G  G  G+ G++G RG  G
Sbjct: 1415 EGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPG 1474

Query: 1044 PPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPG 1103
              GP G +G PGP GE GE G+ GP GP G  G  G AG  GA GP+GPPG  G  G  G
Sbjct: 1475 AIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKG 1534

Query: 1104 EKGEPGE--------SGSPGIQGEPGVKGPRGERGEKGESGQPG--EPGPPGPKGPTGDD 1153
            E G PG+        +G  G +G+ G  GPRG  G +GE G PG   PG PGPKG  GD 
Sbjct: 1535 EPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDR 1594

Query: 1154 GP------------KGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPT 1201
            GP             G PG  G PG PGPPG  GPRG+DG  G++G++G PG PG PG  
Sbjct: 1595 GPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKA 1654

Query: 1202 GENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK------- 1254
            GE G  G  G RGP G  G +G  G  G  G PG+ G  G  G  GP GP G+       
Sbjct: 1655 GERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPG 1714

Query: 1255 ------PGPDGLRGLPGSVGQQGRPGATGQAGPP---GPVGPPGLPGLRGDAGAKGEKGH 1305
                  PG  G  G  G  G  G PGA G+ G     GP GP G PG+RG AG KG++G 
Sbjct: 1715 AREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGP 1774

Query: 1306 PGL---------IGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIG-PG---- 1351
            PGL          G  GP G  G  G  G PG  G PG +GE G+PG SGP G PG    
Sbjct: 1775 PGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGE 1834

Query: 1352 ----------GPPGLPGPAGPKGAKGATGPG------GPKGEKGV------QGPPGHP-- 1387
                      G PG PG  G KG KG +G        GPKGE+G       QGPPG P  
Sbjct: 1835 DGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGP 1894

Query: 1388 -GPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP-TGGAPGSPGGLEEIFGSLD---- 1441
             GPPG+    +P     K  R   GS+    ++ +P   G  G PG +  +   L+    
Sbjct: 1895 VGPPGQGFPGVPGGTGPKGDRGETGSK---GEQGLPGERGLRGEPGSVPNVDRLLETAGI 1951

Query: 1442 ---SLREEIEQMRRPTGT 1456
               +LRE +E     +G+
Sbjct: 1952 KASALREIVETWDESSGS 1969



 Score =  219 bits (558), Expect = 2e-56
 Identities = 138/345 (40%), Positives = 166/345 (48%), Gaps = 27/345 (7%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVE----------GPPGPEGPAGLIGPPGIQGNP 312
            P S    G  GLKG+KG+P V  PG   E          G PG EGP GL GPPG +G  
Sbjct: 2445 PGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGER 2504

Query: 313  GPVGDPGERG-------------PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG-GDKGP 358
            G  GD G  G             PPG  G  G  G  GP G       R  +G  GDKG 
Sbjct: 2505 GEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGS 2564

Query: 359  V-VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGP 417
                  +  A     +  L  +G PG  G  G PG  G+ G PG++GE GD+G  GPRG 
Sbjct: 2565 KGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGL 2624

Query: 418  QGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGP 477
            +G  G  G  G  G  G  G  G PG PG+ G +G  G PG+PG+ G  G  G  G  G 
Sbjct: 2625 KGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGD 2684

Query: 478  PGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGE 537
             G DG+ G  G+ G +G  G  G  G  GP G  G  GPPG  G  GP+GP+G  G +GE
Sbjct: 2685 RGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGE 2744

Query: 538  PGPPGQQ--GTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSD 580
             GPPG++  G PG  G PG +G  G  G  GP+G+ G   +   D
Sbjct: 2745 RGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDD 2789



 Score =  134 bits (338), Expect = 6e-31
 Identities = 90/246 (36%), Positives = 113/246 (45%), Gaps = 45/246 (18%)

Query: 243  RAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGL 302
            R    PQ QP     P   +P S    G  G++GEKG+   +       GP G +G  G+
Sbjct: 2580 RGLLGPQGQPGAAGIPG--DPGSPGKDGVPGIRGEKGDVGFM-------GPRGLKGERGV 2630

Query: 303  IGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAA 362
             G  G+ G  G   D GE GPPGR GL G  G  G PG    +P + G+ G +       
Sbjct: 2631 KGACGLDGEKG---DKGEAGPPGRPGLAGHKGEMGEPG----VPGQSGAPGKE------- 2676

Query: 363  QEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTG 422
                           L GP G  G+ G+PGP G  G  G +G  G  G  GP G  G  G
Sbjct: 2677 --------------GLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAG 2722

Query: 423  PPGKAGRRGRAGADGARGMPGDPGVKGDR--GFDGLPGLPGEKGHRGDTGAQGLPGPPGE 480
            PPG  G  G  G +G +G  G+ G  G+R  G  G+PG PGE+G       QG PGP G 
Sbjct: 2723 PPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGE------QGRPGPAGP 2776

Query: 481  DGERGD 486
             GE+G+
Sbjct: 2777 RGEKGE 2782


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score =  910 bits (2352), Expect = 0.0
 Identities = 571/1348 (42%), Positives = 660/1348 (48%), Gaps = 233/1348 (17%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVLEPGML----VEGPPGPEGPAGLIGPPGIQGNPGPVGDP 318
            P  Q   GP+G  G+KG+    EPG+       GPPG  G  G  G PGI G  GP G P
Sbjct: 63   PGMQGPEGPQGPPGQKGDTG--EPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPP 120

Query: 319  ---------GERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQA 369
                     GERGP G  GLPG  G PGPPG    LP   G  G   G V        + 
Sbjct: 121  GIPGCNGTKGERGPLGPPGLPGFAGNPGPPG----LPGMKGDPGEILGHVPGMLLKGERG 176

Query: 370  IL-------QQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESG--DLGPQGPRGPQGL 420
                           L+GP GP G+TG PGP G PG PG KG+ G    GP+G +G QG+
Sbjct: 177  FPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGV 236

Query: 421  TGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGE 480
            +GPPG  G + +    G     G+ G KG+ GF G+PG+ GEKG  G  G +G PG  G+
Sbjct: 237  SGPPGVPG-QAQVQEKGDFATKGEKGQKGEPGFQGMPGV-GEKGEPGKPGPRGKPGKDGD 294

Query: 481  DGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV------------RGMDGPQGP 528
             GE+G  G  G  G PG  G +G  G KG  G PGPPG+            RG  G  GP
Sbjct: 295  KGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGP 354

Query: 529  KGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEK--------------GPQGKPGLP 574
            +G  GP+G PG PGQ G PG   +PG  GA G  GE+              GP G+ GLP
Sbjct: 355  RGEPGPKGFPGLPGQPGPPGLP-VPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLP 413

Query: 575  GMPGSDGPPGHPG--------KEGPPGTKGNQGPSGPQGPLGYPGPRGVKG-------VD 619
            G PGS GPPG PG        + GPPG +G  G  G  G +G  G +G KG       +D
Sbjct: 414  GPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDID 473

Query: 620  GIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPP 679
            G RG  G +G  GE GFP   G  G KGDRG  G  G  G  GP+G  G  G  G  G P
Sbjct: 474  GYRGPPGPQGPPGEIGFP---GQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEP 530

Query: 680  G-------LMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGP--- 729
            G       L G+KG  G PG PG  GR G  G  G PG PG  G  G+ GL G+ GP   
Sbjct: 531  GEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGG 590

Query: 730  ------RGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG-------LPGPQG 776
                  RG+ GP GP G  GP G  G  G  G  GG G  G PG +G       LPGP G
Sbjct: 591  VGFPGSRGDTGPPGPPGY-GPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPG 649

Query: 777  PNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERG 836
              G PG  G PGP G  G PG PG+ G  G +G  G PG  G  GP G  G  G  G+ G
Sbjct: 650  AEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPG-IGFPGPPGPKGVDGLPGDMG 708

Query: 837  HPGPPGPPGEQGLPGTAGKEGTKGDPGP--------------PGAPGKDGPAGLRGFPGE 882
             PG PG PG  GLPG  G +G KG+PG               PG PG+ G  G+ G PGE
Sbjct: 709  PPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGE 768

Query: 883  RGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAA--GSGGPIGPPGRPGPQGPPGAAGEK 940
             G  G  G  G++G  GP G PG  GSPG  G    G+ GP G  G PG  GPPG  GEK
Sbjct: 769  HGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEK 828

Query: 941  GVPGEKG--PIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHG 998
            G PG  G    GP G  G QG  G+ G +G PG+ G+ G  G  G PG KG  G  G  G
Sbjct: 829  GFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPG 888

Query: 999  PPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPI---------- 1048
             PG PGP+G  G PG  G  G PG+ GP+G  G KGD+G  G  G PG +          
Sbjct: 889  QPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKG 948

Query: 1049 -----GLQGLPGPSGEKGETGDV---------GPMGPPGPPGPRGP---AGPNGADGPQG 1091
                 G +G  GP GEKG  GD          G  G PG PGP+G    +G  GA G  G
Sbjct: 949  QKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPG 1008

Query: 1092 PPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP------------- 1138
            P G VG +G PG  GE G  G PG QG PG+ G +G +GEKG++G P             
Sbjct: 1009 PKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGD 1068

Query: 1139 ----GEPGPPGPKGP---------TGDDGPKGNPGPVGFPGDPGPPGEGGPR---GQDGA 1182
                G PG PG KG           G  G KG+PG VG+PG PG PGE G +   G DG 
Sbjct: 1069 QGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGI 1128

Query: 1183 KGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS--------------PGSEGRQGGK 1228
             G +GE G PG PG  GP G+ G PG  G  G AG               PG++G +G K
Sbjct: 1129 PGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSK 1188

Query: 1229 GAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGS--------VGQQGRPGATGQAG 1280
            G  G PG  G+PG  G  G  G  G PGP G  GLPGS         G +G  G  G  G
Sbjct: 1189 GEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPG 1248

Query: 1281 PPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL---------------------------IG 1313
             PGP+GPPGLPG+ G  G KG  G PG  G+                           +G
Sbjct: 1249 LPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMG 1308

Query: 1314 PPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP----------PGLPGPAGPK 1363
            PPG  G +G +GLPG QG  G +G+ G+PGA G  GP GP          PGLPGP GP 
Sbjct: 1309 PPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPP 1368

Query: 1364 GAKGATGPGGPKGEKGVQGPPGHPGPPG 1391
            G KG  G  GPKG++GV G  G PGPPG
Sbjct: 1369 GLKGLQGLPGPKGQQGVTGLVGIPGPPG 1396



 Score =  803 bits (2074), Expect = 0.0
 Identities = 527/1221 (43%), Positives = 600/1221 (49%), Gaps = 156/1221 (12%)

Query: 212  PGVQAAYESCEQKELECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHGP 271
            PGV    +  E+ +   +G   E+ Q  +P       Q  P    + +  +P  +   G 
Sbjct: 240  PGVPGQAQVQEKGDFATKG---EKGQKGEP-----GFQGMPGVGEKGEPGKPGPRGKPGK 291

Query: 272  RGLKGEKGEPAVL-EPGM--LV--EGPPGPEGPAGLIGPPGIQGNPGPVGD--------- 317
             G KGEKG P    EPG   L+  +GP G +G AG  GPPGI    GP+G+         
Sbjct: 292  DGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGT 351

Query: 318  PGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--GDKGPVVAAQEAQAQAILQQAR 375
            PG RG PG  G PG  G PGPPG  L +P + G+ G  G++G                 R
Sbjct: 352  PGPRGEPGPKGFPGLPGQPGPPG--LPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGR 409

Query: 376  LALRGPPGPMGYTGRP-----------------GPLGQPGSPGLKGESGDLGPQGP---- 414
              L GPPG  G  G+P                 GP G PG PG  GE G+ G +G     
Sbjct: 410  DGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLI 469

Query: 415  ------RGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGL---PGEKGH 465
                  RGP G  GPPG+ G  G+ GA G RG+PG  GV G  G  G PGL   PG KG 
Sbjct: 470  CDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGE 529

Query: 466  ----------RGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPR---GLLGPKGPPG 512
                      +GD G  G PG PG  G  G  G  G  GLPG  G     GL G +GPPG
Sbjct: 530  PGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPG 589

Query: 513  IPGPPGVRGMDGPQGP-----------KGSLGPQGEPGPPG-------------QQGTPG 548
              G PG RG  GP GP           KG  G  G PG PG               G PG
Sbjct: 590  GVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPG 649

Query: 549  TQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP--GKEGPPGTKGNQGPSGPQGP 606
             +GLPG  G  GP G++G  G PG PG+PG  G  G P  G  GPPG KG  G  G  GP
Sbjct: 650  AEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGP 709

Query: 607  LGYPGPRGVKGVDGIRGLKGHKGEKGE-----DGFPGFKGDIGVKGDRGEVGVPGSRGED 661
             G PG  G  G+ G  G++G KGE G       G PG  G  G  G++G +GVPG  GE 
Sbjct: 710  PGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEH 769

Query: 662  GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGL-----PGYPGRQGP---------KGSLG 707
            G  GP G  G  G+PGPPGL G  G  GVPG+      G PG QGP         KG  G
Sbjct: 770  GAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKG 829

Query: 708  FPGF-----PGASGEKGARGL---SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGG 759
            FPGF     PG  G+KGA+GL   +G+SG  G  G  G  G  G  G+ G+ G  GT G 
Sbjct: 830  FPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQ 889

Query: 760  DGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV 819
             G  GP G  GLPG +G +GFPG  GP G PG  G  G  G  G+ G   K       G 
Sbjct: 890  PGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQ 949

Query: 820  VGPQGAAGETGPMGE---RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGL 876
             G QG  G+ GP+GE   RG PG PG PG+ G  G  G+ G KGDPG  G PG  G  G 
Sbjct: 950  KGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGP 1009

Query: 877  RGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGP--IGPPGRPGPQGPP 934
            +G  G  GLPGT G  G+ G  GP G PG  G  G +G  G  GP  IG PG  G +G  
Sbjct: 1010 KGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQ 1069

Query: 935  GAAGEKGVPGEKGPIGPTGRDGVQGPVGL---PGPAGPPGVAGEDGDKGEVGDPGQKGTK 991
            G AG  G PGEKG  G  G  G+ G  GL   PG  G PG  G  G+KG+ G PG  G  
Sbjct: 1070 GIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIP 1129

Query: 992  GNKGEHGPPGPPGPIGPVGQ---------PGAAGADGEPG--ARGPQGHFGAKGDEGTRG 1040
            G KGE G PG PGP GP GQ         PG+AG  GEPG   RG  G  GAKGD+G++G
Sbjct: 1130 GVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKG 1189

Query: 1041 FNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPA--GPNGADGPQGPPGGVGN 1098
              G PG  G  G+PG  GE+G  G  GP G PG PG  G A  GP G  GPQG PG  G 
Sbjct: 1190 EVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGL 1249

Query: 1099 LGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN 1158
             GP G  G PG  G  G +G PG  G  G  G KG+ G  G PG  G  G TG  G  G 
Sbjct: 1250 PGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGP 1309

Query: 1159 PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLG-KRGPAG 1217
            PG  GF G  G PG        G KGD+G+ G PG  G PGP    GPPGP    +G  G
Sbjct: 1310 PGVPGFQGPKGLPG------LQGIKGDQGDQGVPGAKGLPGPP---GPPGPYDIIKGEPG 1360

Query: 1218 SPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATG 1277
             PG EG  G KG +G PG  G  G TG VG  GP G PG D   G PG  G+ G  G TG
Sbjct: 1361 LPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFD---GAPGQKGEMGPAGPTG 1417

Query: 1278 QAGPPGPVGPPGLPGLRGDAG 1298
              G PGP GP GLPG  G  G
Sbjct: 1418 PRGFPGPPGPDGLPGSMGPPG 1438



 Score =  801 bits (2068), Expect = 0.0
 Identities = 507/1161 (43%), Positives = 580/1161 (49%), Gaps = 171/1161 (14%)

Query: 425  GKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLP------GPP 478
            GK    G  G  G RG+PG  GV G  G  G  G  G  G +GDTG  GLP      GPP
Sbjct: 37   GKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPP 96

Query: 479  GEDGERGD---------DGEIGPRGLPGESGPRGLLGPKGPPGI------PGPPGVRGMD 523
            G  G  G+         DG  GP G+PG +G +G  GP GPPG+      PGPPG+ GM 
Sbjct: 97   GASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMK 156

Query: 524  GPQGPKGSLGP----QGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGS 579
            G  G      P    +GE G PG  GTPG  GLPG QG +GP G  GP G PG PG PG 
Sbjct: 157  GDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGE 216

Query: 580  DGPPGHPGKEGPPGTKGNQGPSGPQGPLGY-----------PGPRGVKGVDGIRGLKGHK 628
             G  G    +GP G KG+QG SGP G  G             G +G KG  G +G+ G  
Sbjct: 217  KGQMG-LSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPG-V 274

Query: 629  GEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED------GPEGPKGRTGPTGDPGPPGL- 681
            GEKGE G PG +G  G  GD+GE G PG  GE       G +GP+G  G  G PGPPG+ 
Sbjct: 275  GEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIV 334

Query: 682  -----MGEKGKLGVPGLPGYPGRQGPK-----------------GSLGFPGFPGASGEKG 719
                 +GEKG+ G PG PG  G  GPK                 G  G PGFPG  GEKG
Sbjct: 335  IGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKG 394

Query: 720  ARGLSGKS--GPRGERGPTGPRGQRGPRGATGKSGA-----KGTSGGDGPHGPPGERGLP 772
             RG  G S  GP G  G  GP G  GP G  G +        G  G  GP G PG+ G  
Sbjct: 395  DRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFI 454

Query: 773  GPQGP-------------NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGK------TGP 813
            G  G              +G+ GP GP GPPG+ G PG PG +G+ G  G+       GP
Sbjct: 455  GEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGP 514

Query: 814  PGPPGVVGPQGAAGETGPM-------GERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPG 866
             G PG++G  GA GE G         G++G PG PG PG  G  G+ G++G  G PGP G
Sbjct: 515  QGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKG 574

Query: 867  APGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPP--GPAGSPGERGAAGSGGPIGP 924
            +PG        G  GERG PG  G PG +G+ GP GPP  GPAG  G++G AG  G  G 
Sbjct: 575  SPGS------VGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGS 628

Query: 925  PGRPGPQ----------GPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGP-------- 966
            PG PGP+          GPPGA G  G PG  GP G  G  G  G  GLPG         
Sbjct: 629  PGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPG 688

Query: 967  ---AGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGP--VGQPGAAGADGEP 1021
                GPPG  G DG  G++G PG  G  G  G  G PG  G  G   VG PG  G  G P
Sbjct: 689  IGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLP 748

Query: 1022 GARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPP--GPPGPRG 1079
            G  G  G  G+ G  G  G +G  GP GLQG+ G  G  G  G VG  G P  GPPG RG
Sbjct: 749  GIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARG 808

Query: 1080 PAGPNGADGPQGPPGGVGNLGPPGEKG--EPGESGSPGIQGEPGVKGPRGERGEKGESGQ 1137
            P G  G  G  GPPG  G  G PG  G   PG  G  G QG PG+ G  G  G  G+ G 
Sbjct: 809  PPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGA 868

Query: 1138 PGEPGPPGPKGP---TGDDGPKGNPGPVGFPGDPGP------PGEGGPRGQDGAKGDRGE 1188
            PG PG PG KG     G  G  G+PGPVG PG PG       PG  GPRG  G KGD+G+
Sbjct: 869  PGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGD 928

Query: 1189 DGEPGQPGSPGPT------GENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGK 1242
             G PG+PGS          G+ G  G  G+ GP G  GS G  G  G  G  G  G PG+
Sbjct: 929  VGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQ 988

Query: 1243 TGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1302
             GP G  G +G PG  GL G  GSVG  G PG  G+ G PG  GP G PGL GD GAKGE
Sbjct: 989  PGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGE 1048

Query: 1303 KGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGE---MGIP---------GASGPIGP 1350
            KG  G  G IG PG +GEKGD+G+ G  GSPG+KGE   +GIP         G+ G +G 
Sbjct: 1049 KGQAGPPG-IGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGY 1107

Query: 1351 GGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVD 1410
             G PGLPG  G KG  G  G  G KGE G+ G PG  GP G+  +P    +P        
Sbjct: 1108 PGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIP-------- 1159

Query: 1411 GSRLMQEDEAIPTGGAPGSPG 1431
            GS   + +  +P  G PG PG
Sbjct: 1160 GSAGEKGEPGLPGRGFPGFPG 1180



 Score =  796 bits (2055), Expect = 0.0
 Identities = 495/1116 (44%), Positives = 563/1116 (50%), Gaps = 116/1116 (10%)

Query: 270  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPG-----IQGNPGPVGDPGERG-- 322
            GP G KGE+G P    P     G PGP+G  GL G PG     + G  G  G PGERG  
Sbjct: 338  GPLGEKGERGYPGTPGP----RGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEK 393

Query: 323  ------------PPGRAGLPGSDGAPGPPG----TSLMLPFRFGSGGGDKGPVVAAQEAQ 366
                        P GR GLPG  G+PGPPG    T+ ++  + G  G    P +  Q   
Sbjct: 394  GDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGF 453

Query: 367  AQAILQQARLA----------LRGPPGPMGYTGRPGPLGQPGSPG---LKGESGDLGPQG 413
               I ++ +             RGPPGP G  G  G  GQPG+ G   L G  G  G  G
Sbjct: 454  IGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPG 513

Query: 414  PRGPQGLTGPPGKAGRRGR-------AGADGARGMPGDPGVKGDRGF---DGLPGLPGEK 463
            P+G  GL G PG  G  G         G  G  G PG PG+ G  G    DG PGLPG K
Sbjct: 514  PQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPK 573

Query: 464  GHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMD 523
            G  G  G +G  GPPG  G  G  G+ GP G PG  GP G +G KG  G PG PG  G+ 
Sbjct: 574  GSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGY-GPAGPIGDKGQAGFPGGPGSPGLP 632

Query: 524  GPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPP 583
            GP+G  G + P   PGPPG +G PG+ G PGPQG      ++G  G PG PG+PG  G  
Sbjct: 633  GPKGEPGKIVPL--PGPPGAEGLPGSPGFPGPQG------DRGFPGTPGRPGLPGEKGAV 684

Query: 584  GHPGK--EGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGED-----GF 636
            G PG    GPPG KG  G  G  GP G PG  G  G+ G  G++G KGE G       G 
Sbjct: 685  GQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGL 744

Query: 637  PGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLP-- 694
            PG  G  G  G++G +GVPG  GE G  GP G  G  G+PGPPGL G  G  GVPG+   
Sbjct: 745  PGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPP 804

Query: 695  ---GYPGRQGP---------KGSLGFPGFPGAS-----GEKGARGL---SGKSGPRGERG 734
               G PG QGP         KG  GFPGFPG       G+KGA+GL   +G+SG  G  G
Sbjct: 805  GARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPG 864

Query: 735  PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDG 794
              G  G  G  G+ G+ G  GT G  G  GP G  GLPG +G +GFPG  GP G PG  G
Sbjct: 865  QQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKG 924

Query: 795  LPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE---RGHPGPPGPPGEQGLPG 851
              G  G  G+ G   K       G  G QG  G+ GP+GE   RG PG PG PG+ G  G
Sbjct: 925  DKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAG 984

Query: 852  TAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG 911
              G+ G KGDPG  G PG  G  G +G  G  GLPGT G  G+ G  GP G PG  G  G
Sbjct: 985  QPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKG 1044

Query: 912  ERGAAGSGGP--IGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGL---PGP 966
             +G  G  GP  IG PG  G +G  G AG  G PGEKG  G  G  G+ G  GL   PG 
Sbjct: 1045 AKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGS 1104

Query: 967  AGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQ---------PGAAGA 1017
             G PG  G  G+KG+ G PG  G  G KGE G PG PGP GP GQ         PG+AG 
Sbjct: 1105 VGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGE 1164

Query: 1018 DGEPG--ARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPP 1075
             GEPG   RG  G  GAKGD+G++G  G PG  G  G+PG  GE+G  G  GP G PG P
Sbjct: 1165 KGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLP 1224

Query: 1076 GPRGPA--GPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1133
            G  G A  GP G  GPQG PG  G  GP G  G PG  G  G +G PG  G  G  G KG
Sbjct: 1225 GSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKG 1284

Query: 1134 ESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1193
            + G  G PG  G  G TG  G  G PG  GF G  G PG  G +G  G +G  G  G PG
Sbjct: 1285 DPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPG 1344

Query: 1194 QPGSPGP-------TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPV 1246
             PG PGP        G  GP GP G +G  G PG +G+QG  G  G PG  G PG  G  
Sbjct: 1345 PPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAP 1404

Query: 1247 GPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPP 1282
            G  G  G  GP G RG PG  G  G PG+ G  G P
Sbjct: 1405 GQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTP 1440



 Score =  482 bits (1241), Expect = e-135
 Identities = 300/698 (42%), Positives = 344/698 (49%), Gaps = 96/698 (13%)

Query: 263  PQSQAAHGPRGLKGEKGEP-------AVLEPGML------VEGPPGPEGPAGLIGPPGIQ 309
            P    A GP GL+G +GEP       +V  PG+         GPPG +GP GL GPPGI+
Sbjct: 766  PGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIK 825

Query: 310  GN-----------PGPVGDPGERGPPGRAG------LPGSDGAPGPPGTSLMLPFRFGSG 352
            G            PGP GD G +G PG  G      LPG  GAPG PG     P   G  
Sbjct: 826  GEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPG----FPGSKGEM 881

Query: 353  G--------GDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPG--- 401
            G        G  GPV A      +           GP G  G  G  G +G PG PG   
Sbjct: 882  GVMGTPGQPGSPGPVGAPGLPGEKG--DHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMD 939

Query: 402  ------LKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDG 455
                  +KG+ GD G +G  GP G  G  G  G  G  G DG  G PG PG KGD G  G
Sbjct: 940  KVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISG 999

Query: 456  LPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPG 515
             PG PG  G +G  G  GLPG PGE G  G  G  G  GLPG+ G +G  G  GPPGI G
Sbjct: 1000 TPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGI-G 1058

Query: 516  PPGVRGMDGPQG------------PKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHG 563
             PG+RG  G QG             KGS+G  G PG PG +G+PG+ G PG  G  G  G
Sbjct: 1059 IPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKG 1118

Query: 564  EKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGV--KGVDGI 621
            +KG  G  G+PG+ G  G PG PG  GP G KG  G  G  G  G  G  G+  +G  G 
Sbjct: 1119 DKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGF 1178

Query: 622  RGLKGHKGEKGEDGFPGFKGDIGVKGDRGE---VGVPGSRGEDG--------PEGPKGRT 670
             G KG KG KGE GFPG  G  G+ G +GE   +G PG +G+ G         EGPKG  
Sbjct: 1179 PGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDR 1238

Query: 671  GPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPR 730
            GP G PG PGL    G +G PGLPG  G +G KG+ G+PG PG  G KG  G  G  G  
Sbjct: 1239 GPQGQPGLPGL---PGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIG 1295

Query: 731  GERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPP 790
            G  G TG +G  GP G  G  G KG  G  G  G  G++G+PG +G    PGP GPPGP 
Sbjct: 1296 GSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKG---LPGPPGPPGP- 1351

Query: 791  GKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLP 850
                   +   +GE G  G  GPPG  G+ G  G  G+ G  G  G PGPPG PG  G P
Sbjct: 1352 -------YDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAP 1404

Query: 851  GTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGT 888
            G  G+ G  G  GP G PG  GP GL   PG  G PGT
Sbjct: 1405 GQKGEMGPAGPTGPRGFPGPPGPDGL---PGSMGPPGT 1439



 Score =  416 bits (1069), Expect = e-116
 Identities = 246/574 (42%), Positives = 293/574 (51%), Gaps = 84/574 (14%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVL-EPGML-------VEGPPGPEGPAGLIGP--------- 305
            P S    G  GLKG+KG+  +  +PG +       ++G  G +G  G IGP         
Sbjct: 911  PGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGD 970

Query: 306  ---PGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAA 362
               PG+ G  G  G PG+ GP G  G+ G+ GAPG PG         GS GG        
Sbjct: 971  PGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPK-------GSVGG-------- 1015

Query: 363  QEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGP-------- 414
                         + L G PG  G  G PGP G PG PG KG  G+ G  GP        
Sbjct: 1016 -------------MGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGL 1062

Query: 415  ---RGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRG---FDGLPGLPGEKGHRGD 468
               +G QG+ G PG  G +G  G+ G  GMPG PG+KG  G   + G PGLPGEKG +G 
Sbjct: 1063 RGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGL 1122

Query: 469  TGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGP 528
             G  G+PG  GE G  G  G  GP G  GE G  G+ G  G  G PG PG RG  G  G 
Sbjct: 1123 PGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPG-RGFPGFPGA 1181

Query: 529  KGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPG--SDGPPGHP 586
            KG  G +GE G PG  G+PG  G  G QG +GP    GPQG+PGLPG PG  ++GP G  
Sbjct: 1182 KGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGP---PGPQGQPGLPGSPGHATEGPKGDR 1238

Query: 587  GKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVK 646
            G +G PG  G  GP GP G         + G+DG++G KG+ G  G  G PG KGD G +
Sbjct: 1239 GPQGQPGLPGLPGPMGPPG---------LPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQ 1289

Query: 647  GDRG---EVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPK 703
            G  G     G+ GS+G+ GP G  G  GP G PG  G+ G++G  GVPG  G PG  GP 
Sbjct: 1290 GMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPP 1349

Query: 704  GSL----GFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGG 759
            G      G PG PG  G  G +GL G  GP+G++G TG  G  GP G  G  GA G  G 
Sbjct: 1350 GPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGE 1409

Query: 760  DGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKD 793
             GP GP G RG PGP GP+G PG  GPPG P  D
Sbjct: 1410 MGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSVD 1443



 Score =  256 bits (654), Expect = 1e-67
 Identities = 165/390 (42%), Positives = 186/390 (47%), Gaps = 57/390 (14%)

Query: 1095 GVGNLGPPGEKGEPGESGSPGIQGE---PGVKGPRGERGEKGESGQPGEPGPPGPKGPTG 1151
            G G     G KG+ GE G PG+QG    PG++GP G +G  G+ G  GEPG PG KG  G
Sbjct: 35   GCGKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRG 94

Query: 1152 DDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLG 1211
              G  G PG    PG PG PG+ GP G  G  G  G  GE G  G PG  G  G PGP G
Sbjct: 95   PPGASGYPGN---PGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPG 151

Query: 1212 KRGPAGSPGS----------EGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLR 1261
              G  G PG           +G +G  G  G PG  G PG  GPVGP G  G PGP G  
Sbjct: 152  LPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPP 211

Query: 1262 GLPGSVGQQGR--PGATGQAGPPGPVGPPGLPGL-----RGDAGAKGEKGHPGLIGLIGP 1314
            G PG  GQ G    G  G  G  G  GPPG+PG      +GD   KGEKG  G  G  G 
Sbjct: 212  GPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGM 271

Query: 1315 PGEQGEKGDRGLPGPQGSPGQ---KGEMGIP------------------GASGPIGPGGP 1353
            PG  GEKG+ G PGP+G PG+   KGE G P                  G  G  GP GP
Sbjct: 272  PG-VGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGP 330

Query: 1354 PGL---PGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQ---------M 1401
            PG+    GP G KG +G  G  GP+GE G +G PG PG PG    P+P Q          
Sbjct: 331  PGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGER 390

Query: 1402 PKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1431
             +K  R   G+ L          G PGSPG
Sbjct: 391  GEKGDRGFPGTSLPGPSGRDGLPGPPGSPG 420


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score =  910 bits (2352), Expect = 0.0
 Identities = 581/1426 (40%), Positives = 697/1426 (48%), Gaps = 207/1426 (14%)

Query: 72   TRQLFPGGFPKDFSLLTVVRTRPGLQAP---LLTLYSAQGVRQLGLELGRPVRFLYEDQT 128
            T  +FP G P +++ +T  R R   +     +  +     + Q+ + L    + +  +  
Sbjct: 281  TEDVFPQGLPDEYAFVTTFRFRKTSRKEDWYIWQVIDQYSIPQVSIRLDGENKAVEYNAV 340

Query: 129  GRPQPPSQPVFRGL---SLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSARPVLDT 185
            G  +   + VFRG     L D  WH++A++++ Q+V+L +DC   + + LP   R  +D 
Sbjct: 341  GAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNVSLHIDCA--LVQTLPIEERENIDI 398

Query: 186  HGVIIFGARILDEEVFEGDVQELAIV-PGVQAAYESCEQKELECEGGQRERPQNQQPHRA 244
             G  + G R+ D    + D+Q + I      A  E+C     +   G  +     +P   
Sbjct: 399  QGKTVIGKRLYDSVPIDFDLQRIVIYCDSRHAELETC----CDIPSGPCQVTVVTEP--- 451

Query: 245  QRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIG 304
               P   P R   P +++             GEKGE  V              GP GL G
Sbjct: 452  --PPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVA-------------GPMGLPG 496

Query: 305  PPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQE 364
            P G  G  GPVG PG +G  G  G+       GP             G G+KG       
Sbjct: 497  PKGDIGAIGPVGAPGPKGEKGDVGI-------GP------------FGQGEKG------- 530

Query: 365  AQAQAILQQARLALRGPP---GPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLT 421
                   ++  L L GPP   G  G  G PG LG+PG P      G++G +GP+GP GL 
Sbjct: 531  -------EKGSLGLPGPPGRDGSKGMRGEPGELGEPGLP------GEVGMRGPQGPPGLP 577

Query: 422  GPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED 481
            GPP   GR G  G  G RG  G  G KG+RG DG PG PG+ G +G  G  G+ GP    
Sbjct: 578  GPP---GRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGP---Q 631

Query: 482  GERGDDGEIGPRGLPGE-------------SGPRGLLGPKGPPGIPGPPGVRGMDGPQGP 528
            GE+GD G  GP G+PG               GPRG  G  GPPG  GP G  G DGP G 
Sbjct: 632  GEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGL 691

Query: 529  KGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGK 588
            +G  G +G+ GPPG  G  G QG PGP G  GP    GP G PGLPG  G  G PG PG 
Sbjct: 692  QGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGP---PGPGGSPGLPGEIGFPGKPGPPGP 748

Query: 589  EGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGD 648
             GPPG  G  GP GP G  G PG RG  G+ G  GL+G  GE+G  G PG KG+ G+   
Sbjct: 749  TGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLP-- 806

Query: 649  RGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPG----------YPG 698
             G  G PG RGE G +G KG  G  G  G  G  GE G  G PGLPG           PG
Sbjct: 807  -GAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPG 865

Query: 699  RQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSG 758
             QGPKG  G PG PG        GL G+ G  G +GPTGP G +G  GA G  GA G  G
Sbjct: 866  EQGPKGEKGDPGLPGEP------GLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPG 919

Query: 759  GDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGP---PG 815
                   PG  G PGP GP G  G  G  G PGKDG  G  G  GE G  G  GP   PG
Sbjct: 920  A------PGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPG 973

Query: 816  PPGVVGPQGAAGETGPMGERGHPGPPGP-----------------------PGEQGLPGT 852
             PG+ GP G  G+ G  G RG PG PGP                        G++G PG 
Sbjct: 974  APGLPGPPG-KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGI 1032

Query: 853  AGKEGTKGDP--GPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 910
             G  G++GDP  G  G PG  GP G +G PG RGLPG  G  G  G +G  G PG  G P
Sbjct: 1033 PGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPP 1092

Query: 911  GERGAAG--SGGPIG----------PPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 958
            G+ G +   S G I           PPG PG  G PG  G+KGVPG+ G  G  G+ G  
Sbjct: 1093 GKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEA 1152

Query: 959  GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGAD 1018
            GP GLP   GPPG+AG  G +GE G  G+ G KG++G    PG PG +GP G PG  GAD
Sbjct: 1153 GPPGLP---GPPGIAGPQGSQGERGADGEVGQKGDQGH---PGVPGFMGPPGNPGPPGAD 1206

Query: 1019 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1078
            G  GA GP G  G+ G EG     GP GP GL G+PG  G++G  G  GP G PG  G  
Sbjct: 1207 GIAGAAGPPGIQGSPGKEGP---PGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEP 1263

Query: 1079 GPAGPNGADGPQGPPGGVGNLGPPGEKGE------PGESGSPGIQGEPGVKGPRGERGEK 1132
            G  GP GA GP G  G  G+ G PG +GE      PG+ G PG  G+ G  GP+G +G +
Sbjct: 1264 GLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPR 1323

Query: 1133 GESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEP 1192
            G  G+ G PG PG  GP+G  G KG+ G  G PG PG  G  GP G+ G KG  G++G P
Sbjct: 1324 GPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVP 1383

Query: 1193 GQPGSPGPTGENGPPGPLGKRGP---AGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPA 1249
            G+PG PG  GE G PG  G +GP    G PG  G  G KG  G  G  G PG+ GPVGP 
Sbjct: 1384 GKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPP 1443

Query: 1250 GPAGKPGPDGLRG-----------LPGSVGQQ----------GRPGA--TGQAGPPGPVG 1286
            GP G+PG  GLRG           +   +G+Q            P A      G PGP G
Sbjct: 1444 GPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPG 1503

Query: 1287 PPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASG 1346
            PPG  GL G AG  GE G PG  GL GP G  G KG+RG  G  G+PG    +G+ G  G
Sbjct: 1504 PPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG----VGLRGEMG 1559

Query: 1347 PIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGE 1392
            P G  G PG PG A   G  G  GP G  G  G  G PG PGPPG+
Sbjct: 1560 PPGIPGQPGEPGYA-KDGLPGIPGPQGETGPAGHPGLPGPPGPPGQ 1604



 Score =  865 bits (2235), Expect = 0.0
 Identities = 521/1172 (44%), Positives = 586/1172 (50%), Gaps = 178/1172 (15%)

Query: 391  PGPLGQPGSPGLKGESGDLG------PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGD 444
            P P  +P +PG + + G L       P G +G  G+ GP G  G +G  GA G  G PG 
Sbjct: 454  PPPPQRPPTPGSE-QIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGP 512

Query: 445  PGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGE---RGDDGEIGPRGLPGESGP 501
             G KGD G       P  +G +G+ G+ GLPGPPG DG    RG+ GE+G  GLPGE G 
Sbjct: 513  KGEKGDVGIG-----PFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGM 567

Query: 502  RGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP------PGQQGTPGTQGLPGP 555
            RG   P+GPPG+PGPPG  G  G QG +G  G +GE G       PG+ G  G QG PGP
Sbjct: 568  RG---PQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGP 624

Query: 556  QGAIGPHGEKGPQGKPGLPGMPGS-------------DGPPGHPGKEGPPGTKGNQGPSG 602
             G  GP GEKG  G  G PG+PGS              GP GH G  GPPG +G  GP G
Sbjct: 625  SGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEG 684

Query: 603  PQGPLGYPGPRGVKG---VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRG 659
              GP G  G RG KG     GI GL G +G  G  G PG  G  G  G  GE+G PG  G
Sbjct: 685  RDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPG 744

Query: 660  EDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKG 719
              GP GP G+ GP G PGPPG  GE G+ G  GLPG PG +G  G  G  G PG  GE G
Sbjct: 745  PPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAG 804

Query: 720  ARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGL--PGPQGP 777
              G  G  G RGE+G  G +G+ G  G  G  G KG +G  GP G PG   L  P P+ P
Sbjct: 805  LPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMP 864

Query: 778  NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 837
             G  GPKG  G PG  G PG  G+ GE+G QG TGPPG  G  G  GA G  G  G  GH
Sbjct: 865  -GEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGH 923

Query: 838  ---PGPPGPPGEQGLPG---------------TAGKEGT------KGDPGPPGAPG---- 869
               PGP GPPG  G PG                AG+EG+      +GDPG PG PG    
Sbjct: 924  VGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGK 983

Query: 870  -KDGPAGLRGFPG-----------------------------ERGLPGTAGGPGLKGNEG 899
             KDG  GLRG PG                             +RG PG  G PG +G+ G
Sbjct: 984  GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPG 1043

Query: 900  --PSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGV 957
               +GPPGP+G PG++G+ GS G    PG PGPQGP G  G  G PGE+GP G  G   +
Sbjct: 1044 IGVAGPPGPSGPPGDKGSPGSRGL---PGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSL 1100

Query: 958  QGPVGL------------PGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGP 1005
              P  +            PGP G PG+ G  GDKG  G PG++GT+G KGE GPPG PGP
Sbjct: 1101 LSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGP 1160

Query: 1006 ---IGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGE 1062
                GP G  G  GADGE G +G QGH G  G  G  G  GPPG  G+ G  GP G +G 
Sbjct: 1161 PGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGS 1220

Query: 1063 TGDVGPMGPPGP---PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQG- 1118
             G  GP GP GP   PG  G  G  G DG  GPPG  G  G PG  G  G  G PG +G 
Sbjct: 1221 PGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGH 1280

Query: 1119 --EPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGP 1176
              + G  GPRGE G  G  GQ G PG  G  GPTG  GP+G  GP G  G PG PGE GP
Sbjct: 1281 TGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGP 1340

Query: 1177 RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGA 1236
             G  G KG +GE+G PG PG  GP G  G PG  G  G  G PG  G  G KG +GDPG 
Sbjct: 1341 SGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGI 1400

Query: 1237 IGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGD 1296
                G  GP G  G  G PG  G +G  G +G QG PG  G  GPPGP G PG PGLRG+
Sbjct: 1401 ---KGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGE 1457

Query: 1297 A-----------------------------------------GAKGEKGHPGLIGLIGPP 1315
            +                                         G  G  G  GL G  GP 
Sbjct: 1458 SPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPM 1517

Query: 1316 GEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPG-----GPPGLPGPAGPKG--AKGA 1368
            GE G  G  GL GP G  G KGE G  G  G  G G     GPPG+PG  G  G    G 
Sbjct: 1518 GEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGL 1577

Query: 1369 TGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQ 1400
             G  GP+GE G  G PG PGPPG   Q  P Q
Sbjct: 1578 PGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQ 1609



 Score =  723 bits (1865), Expect = 0.0
 Identities = 444/1038 (42%), Positives = 498/1038 (47%), Gaps = 168/1038 (16%)

Query: 259  QNQEPQSQAAHGPRGLKGE---KGEPAVLEPGMLVE--------GPPGPEGPAGLIGPPG 307
            Q   P      GP+G KG+    G P V  PG +V+        G PGP G  G  GPPG
Sbjct: 618  QQGRPGPSGVAGPQGEKGDVGPAGPPGV--PGSVVQQEGLKGEQGAPGPRGHQGAPGPPG 675

Query: 308  IQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQA 367
             +G   P+G  G  GPPG  GL G  G  GPPG                           
Sbjct: 676  ARG---PIGPEGRDGPPGLQGLRGKKGDMGPPGI-------------------------- 706

Query: 368  QAILQQARLALRGPPGPMGYTGRPGPLGQPGSP---GLKGESGDLGPQGPRGPQGLTGPP 424
                    L L+GPPGP G  G PGP G PG P   G  G+ G  GP GP G  G  GPP
Sbjct: 707  -----PGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPP 761

Query: 425  GKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGER 484
            G  G +G  G  G  G+PG PG++G+ G  GL G PGEKG  G  GA G PG  GE G++
Sbjct: 762  GPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQ 821

Query: 485  GDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV----RGMDGPQGPKGSLGPQGEPGP 540
            G+ GE+G  GL G+ G +G  GP GPPG+PG   +      M G QGPKG  G  G PG 
Sbjct: 822  GEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGE 881

Query: 541  PGQQGTP------GTQGLPGPQGAIGPHGEKGPQGKPGLP---GMPGSDGPPGH---PGK 588
            PG QG P      G  G PG +G  G HG  G  G PG P   G PG  GPPG    PG 
Sbjct: 882  PGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGL 941

Query: 589  EGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIG---- 644
             G PG  G +G  G  G  G PGP G +G  G  GL G  G KG+DG PG +G  G    
Sbjct: 942  RGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPGLPGP 1000

Query: 645  ----------------------VKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLM 682
                                  VKGDRG  G+PGS G  G  G     G  G PGP G  
Sbjct: 1001 LGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPG----IGVAGPPGPSGPP 1056

Query: 683  GEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSG---------------KS 727
            G+KG  G  GLPG+PG QGP G  G PG PG  G  G  GLS                  
Sbjct: 1057 GDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCND 1116

Query: 728  GPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPP 787
             P G  G  G  G +G +G  GK G +GT G  G  GPPG  G PG  GP G  G +G  
Sbjct: 1117 CPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGAD 1176

Query: 788  GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ 847
            G  G+ G  GHPG  G +G  G  GPPG  G+ G  G  G  G  G+ G PGP GP G  
Sbjct: 1177 GEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLP 1236

Query: 848  GLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPA 907
            G+PG  GKEG  G PGPPG PGK G  GL G  G RG PG  G  G  G  GP G  G  
Sbjct: 1237 GIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAM 1296

Query: 908  GSPGERGAAGSG---GPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLP 964
            G PG+ G  G     GP GP G  GP+GPPG  G  G PGE GP G  G+ G +G  G P
Sbjct: 1297 GLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSP 1356

Query: 965  ------GPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGAD 1018
                  GP GPPG  GE G  G+ G PG+ G  G KGE G PG  G  GP   PG  G  
Sbjct: 1357 GLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGP---PGGKGQP 1413

Query: 1019 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDV------------ 1066
            G+PG  G +GH G  G +G  G NGP GP G  G PG  G +GE+  +            
Sbjct: 1414 GDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELG 1473

Query: 1067 --------------------GPMGPPGPPGPRGPAGPNGADGPQGPPG--GVGNL-GPPG 1103
                                   G PGPPGP G  G  G  GP G PG  G G L GP G
Sbjct: 1474 KQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSG 1533

Query: 1104 EKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEP-----GPPGPKGPTGDDGPKGN 1158
              G  GE G+ G  G PGV G RGE G  G  GQPGEP     G PG  GP G+ GP G+
Sbjct: 1534 PIGPKGERGAKGDPGAPGV-GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGH 1592

Query: 1159 PGPVGFPGDPGPPGEGGP 1176
            P   G PG PGPPG+  P
Sbjct: 1593 P---GLPGPPGPPGQCDP 1607



 Score =  712 bits (1837), Expect = 0.0
 Identities = 440/1065 (41%), Positives = 508/1065 (47%), Gaps = 184/1065 (17%)

Query: 246  RSPQQQPSRLHRPQNQ-EPQSQAAHGPRGLKGEKGEPAVL----EPGML----------V 290
            R PQ  P     P     P  Q   G +G +GEKGE  +     +PG            V
Sbjct: 568  RGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGV 627

Query: 291  EGPPGPEGPAGLIGPPGI-------------QGNPGPVGDPGERGPPGRAGLPGSDGAPG 337
             GP G +G  G  GPPG+             QG PGP G  G  GPPG  G  G +G  G
Sbjct: 628  AGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDG 687

Query: 338  PPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQP 397
            PPG   +   +     GD GP                 L L+GPPGP G  G PGP G P
Sbjct: 688  PPGLQGLRGKK-----GDMGPPGIP-----------GLLGLQGPPGPPGVPGPPGPGGSP 731

Query: 398  GSPGLKGESGDLGPQGPRGPQGL---TGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFD 454
            G PG  G  G  GP GP GP G     GPPG  G +G  G  G  G+PG PG++G+ G  
Sbjct: 732  GLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQ 791

Query: 455  GLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIP 514
            GL G PGEKG  G  GA G PG  GE G++G+ GE+G  GL G+ G +G  GP GPPG+P
Sbjct: 792  GLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLP 851

Query: 515  GPPGV----RGMDGPQGPKGSLGPQGEPGPPGQQGTPGT------QGLPGPQGAIGPHGE 564
            G   +      M G QGPKG  G  G PG PG QG PG        G PG +G  G HG 
Sbjct: 852  GTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGA 911

Query: 565  KGPQGKPGLPG---MPGSDGPPGH---PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGV 618
             G  G PG PG    PG  GPPG    PG  G PG  G +G  G  G  G PGP G +G 
Sbjct: 912  PGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGD 971

Query: 619  DGIRGLKGHKGEKGEDGFPGFKGDIG--------------------------VKGDRGEV 652
             G  GL G  G KG+DG PG +G  G                          VKGDRG  
Sbjct: 972  PGAPGLPGPPG-KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAP 1030

Query: 653  GVPGSRGE-----------DGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQG 701
            G+PGS G             GP GP G  G  G  G PG  G +G  G  G PG PG +G
Sbjct: 1031 GIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERG 1090

Query: 702  PKGSLGF---------------------------PGFPGASGEKGARGLSGKSGPRGERG 734
            P G  G                            PG PG  G+KG  G  G+ G  G++G
Sbjct: 1091 PPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKG 1150

Query: 735  PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDG 794
              GP G  GP G  G  G++G  G DG  G  G++G PG  G   F GP G PGPPG DG
Sbjct: 1151 EAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPG---FMGPPGNPGPPGADG 1207

Query: 795  LPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG 854
            + G  G  G  G  GK GPPGP G  G  G  GE G  G  G PGPPG PG+ G PG  G
Sbjct: 1208 IAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPG 1267

Query: 855  KEGTKGDPG------PPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP----- 903
             EG +G PG        GAPG  G +G  G PG+ GLPG  G  G  G +GP GP     
Sbjct: 1268 PEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPG 1327

Query: 904  ----------PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTG 953
                      PGP+G+PG++G+ G  G  G PG  GP+GPPG  GEKGVPG++G  G  G
Sbjct: 1328 KNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPG 1387

Query: 954  RDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPG 1013
              G +G  G PG  G  G     G KG+ GDPG  G KG+ G  GP G PG  GPVG PG
Sbjct: 1388 EPGFKGERGDPGIKGDKG---PPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPG 1444

Query: 1014 AAGADGEPGARGP-----------QGHFGAKGD---------------EGTRGFNGPPGP 1047
              G  G PG RG            Q   G + +               + ++G  GPPGP
Sbjct: 1445 PPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGP 1504

Query: 1048 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG-GV-GNLGPPGEK 1105
             G  GLPG +G  GE G  G  G  GP GP GP G  GA G  G PG G+ G +GPPG  
Sbjct: 1505 PGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIP 1564

Query: 1106 GEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1150
            G+PGE G     G PG+ GP+GE G  G  G PG PGPPG   P+
Sbjct: 1565 GQPGEPGYAK-DGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPS 1608



 Score =  506 bits (1304), Expect = e-143
 Identities = 329/841 (39%), Positives = 389/841 (46%), Gaps = 130/841 (15%)

Query: 212  PGVQAAY-ESCEQKELECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHG 270
            PGV+    +  E+ EL   G + +R +  +   A        + L  P  + P  Q   G
Sbjct: 812  PGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQ---G 868

Query: 271  PRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLP 330
            P+G KG+ G P   EPG+  +G PG  GP G  GPPG +G  G  G PG  G PG  G  
Sbjct: 869  PKGEKGDPGLPG--EPGL--QGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHV 924

Query: 331  GSDGAPGPPGTSLMLPFRFGSGG--GDKGPVVAAQEAQAQAIL----QQARLALRGPPGP 384
            G+ G  GPPG S+  P   G+ G  G++G   AA E  +   +          L GPPG 
Sbjct: 925  GAPGPSGPPG-SVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGK 983

Query: 385  MGYTGRPGPLGQPGSPG-----------------------LKGESGDLGPQGPRGPQG-- 419
             G  G PG  G PG PG                       +KG+ G  G  G  G +G  
Sbjct: 984  -GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDP 1042

Query: 420  ---LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGL-- 474
               + GPPG +G  G  G+ G+RG+PG PG +G  G DG PG PGE+G  G  G   L  
Sbjct: 1043 GIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLS 1102

Query: 475  ----------------PGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPG 518
                            PGPPG  G  G  G+ G  G PG  G  G  G  GPPG+PGPPG
Sbjct: 1103 PGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPG 1162

Query: 519  VRGMDGPQGPKGS------------------LGPQGEPGPPGQQGTPGTQGLPGPQGAIG 560
            + G  G QG +G+                  +GP G PGPPG  G  G  G PG QG+ G
Sbjct: 1163 IAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPG 1222

Query: 561  PHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDG 620
              G  GPQG  GLPG+PG +G  G  GK GPPG  G  G  G  GP G  GP G KG  G
Sbjct: 1223 KEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTG 1282

Query: 621  IRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPG 680
              G  G +GE G  G PG +G  G  GD G  G  G +G  GP G  G  G  G+PGP G
Sbjct: 1283 DSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSG 1342

Query: 681  LMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRG 740
              G+KG  G  G PG PG  GP+G  G PG  G  G++G  G  G+ G +GERG  G +G
Sbjct: 1343 TPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKG 1402

Query: 741  QRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPG 800
             +GP G  G+ G  G          PG +G  G  GP G PG  GP GPPG  G PG PG
Sbjct: 1403 DKGPPGGKGQPGDPGI---------PGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPG 1453

Query: 801  QRG--------------EVGFQGKT------------------GPPGPPGVVGPQGAAGE 828
             RG              E+G Q +T                  G PGPPG  G  G  G 
Sbjct: 1454 LRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGR 1513

Query: 829  TGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGT 888
             GPMGE G PG  G  G  G  G  G+ G KGDPG PG        GLRG  G  G+PG 
Sbjct: 1514 AGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG-------VGLRGEMGPPGIPGQ 1566

Query: 889  AGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGE-KG 947
             G PG    +G  G PGP G  G  G  G  GP GPPG+  P      A     PG  KG
Sbjct: 1567 PGEPGY-AKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKG 1625

Query: 948  P 948
            P
Sbjct: 1626 P 1626


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
            sapiens]
          Length = 1424

 Score =  895 bits (2312), Expect = 0.0
 Identities = 594/1412 (42%), Positives = 686/1412 (48%), Gaps = 271/1412 (19%)

Query: 270  GPRGLKGEKGEPAVL-EPGML----VEGPPGPEGPAG---------------LIGPPGIQ 309
            G +G KGEKG P     PG       EG PGP+GP G               + G PG  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 310  GNPGPVGDPGERGPPGRAGLPGSDGA------PGPPGTSLMLPFRFGSGG--GDKGPVVA 361
            G+PG  G PG  GP G  G+PG  G+      PG PGT L  P   G+ G  G KG    
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGT-LGYPGIPGAAGLKGQKGAPAK 161

Query: 362  AQEAQAQAILQQARLALRGPPGPMGYTGRPG---PLGQPGSPGLKGESGDLGPQGP---- 414
             ++ +  A   +    L G PGP G  G PG   P+G PG PG  G  G +GP+GP    
Sbjct: 162  EEDIELDA---KGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHM 218

Query: 415  ----------RGPQGLTGPPGKAGR--------------RGRAGADGA------------ 438
                      RG +GLTGPPG  G               +G  G  GA            
Sbjct: 219  GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGL 278

Query: 439  --------RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI 490
                    +G PGDPG++G  G DG+PG PG +G +G+   +G PG  GEDG +G  G+I
Sbjct: 279  PGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN---RGFPGLMGEDGIKGQKGDI 335

Query: 491  GP------------------RGLPGESGPRGLLGPKGP---PGIPGPPG-----VRGMDG 524
            GP                   G PG  GPRG  GP+GP   PG+PG PG     +RG  G
Sbjct: 336  GPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPG 395

Query: 525  PQGPKGSLGPQGEPGP-----PGQQGTPGTQGLPGPQGAIGPHGE----KGPQGKPGLPG 575
              G KGS G +G PG      PG  G  G+ GLPG  G  GP G+    KGP G  GLPG
Sbjct: 396  WPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPG 455

Query: 576  MPGSDGPPGHPGKEGPPGTKGNQGP--SGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGE 633
              GS G PG  G +G PG    Q P   GP G  G PG  GVKG+ G +G  G KG  G 
Sbjct: 456  YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515

Query: 634  DG---------FPGFKGDIGVKGDRGE-------VGVPGSRGEDGPEGPKGRTGPTGDPG 677
             G         FPG +GD G+KG++GE       VGVPG  G  G  G KG  G  G PG
Sbjct: 516  PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575

Query: 678  PPGLMGEKGKL------------GVPGLPGYPGRQGPKGSLGF-----PGFPGASGEKGA 720
              GL G KG+L            G PG PG PG  GP G  G+     PG  G  G  GA
Sbjct: 576  VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635

Query: 721  RGLSGKSGPRGER----------GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG 770
             G  G++GPRGE           GP GP G  GP+G  G  G+ G  G  G  GP GE G
Sbjct: 636  PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPG 695

Query: 771  LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP--------PGVVGP 822
            +PG   P G PGPKG  G PG  G  G PG+ GE G  GK G PG         PG  G 
Sbjct: 696  IPGIGFP-GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGT 754

Query: 823  QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE 882
             G  GE G  GE G  G PG PG  G PG  G +G +GDPG PG PG+ GP G R   G 
Sbjct: 755  PGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPG-RCIEGP 813

Query: 883  RGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSG--GPIGPPGRPGPQGPPGAAGEK 940
            RG  G  G  GLKG +G  G  GP G PG  G   SG  G  G PG PG QG  G  G++
Sbjct: 814  RGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQR 873

Query: 941  GVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPG------QKGTKGNK 994
            G PG  G +GP G DGV G +G PG  GPPG  G  G  G+ G PG      Q+GT G K
Sbjct: 874  GYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAK 933

Query: 995  GEHGPPGPPGP------IGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPI 1048
            GE G  G PGP      IG  G+PG  G  G PG            ++G RG  G PG  
Sbjct: 934  GEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPG------------EKGNRGVPGMPGLK 981

Query: 1049 GLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP 1108
            GL+GLPGP+G  G  GD+G  G PG PG RG  G  G  G  G  G  G LG PG  G P
Sbjct: 982  GLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRP 1041

Query: 1109 GESGSPGIQGE-----------PGVKGPRGERG---EKGESGQPGEPGPPGPKGPTGDDG 1154
            G  G  G+QG+           PG  GP G+ G   + G+ G+ G+PGPPG  GP G +G
Sbjct: 1042 GLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101

Query: 1155 PKGNPGPVGFPGDPGPPGEGGPRGQDGAKGD---RGEDGEPGQPGSPGPTG------ENG 1205
              G+PG  G PG PGP G+ G +G  G  G    RG  G PG PGSPGP G       +G
Sbjct: 1102 APGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDG 1161

Query: 1206 PPGPLGKRGPAG----SPGSEGRQGGKGAKGD---------PGAIGAPGKTGPVGPAGPA 1252
             PGP G++G  G     PG  G  G +GAKGD         PG  GA G  GP GP G  
Sbjct: 1162 IPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIE 1221

Query: 1253 GKPGPDGLRG--LPGSVGQQGRPGATGQAGPPGPVGPPG--LPGLRGDAGAKGE---KGH 1305
            G PGP GL G  +PG  G +G PG+ G  G PGP GPPG  + G++GD G+ G    KG 
Sbjct: 1222 GFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP 1281

Query: 1306 PGLIGLIGPPGEQGEKGDRGLPGP------QGSPGQKGEMGIPGASGPIGPGGPPGLPGP 1359
            PG  G +GPPG  G  G  GLPGP      QG PG KGE G PG  G IGP GP G  GP
Sbjct: 1282 PGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGP 1341

Query: 1360 AGPKG---------AKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVD 1410
             G +G           G+ GP G  GE G+QG PG PGPPG +    P   P K     D
Sbjct: 1342 PGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGK-----D 1396

Query: 1411 GSRLMQEDEAIPTG--GAPGSPGGLEEIFGSL 1440
            G    +     P G  G  GS G  E +F  L
Sbjct: 1397 G----KPGTPGPAGEKGNKGSKGEPESLFHQL 1424



 Score =  861 bits (2224), Expect = 0.0
 Identities = 545/1291 (42%), Positives = 633/1291 (49%), Gaps = 213/1291 (16%)

Query: 262  EPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGER 321
            +P    A GP+GL G  G P          GP GP GP G  G PG  G  GP G  GER
Sbjct: 172  DPGLPGAPGPQGLPGPPGFP----------GPVGPPGPPGFFGFPGAMGPRGPKGHMGER 221

Query: 322  --GPPGRAGLPGSDGAPGPPGTSLML----PFRFGSGG--GDKGPVVAAQEAQAQAILQQ 373
              G  G  G+ G  G PGPPGT ++       R    G  GDKG +          +  +
Sbjct: 222  VIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGE 281

Query: 374  ARLALRGPPGPMGYTGRPGPLGQPGSPG------------------LKGESGDLGPQGPR 415
            +  + +G PG  G  G+PG  G PG PG                  +KG+ GD+GP G R
Sbjct: 282  SYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFR 341

Query: 416  GP------------QGLTGPPGKAGRRGRAGADGARGMPGDPGVK--GDRGFDGLPGLPG 461
            GP            +G  GPPG  G RG  G  G  G+PG PG    G RG  G PGL G
Sbjct: 342  GPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKG 401

Query: 462  EKGHRGD--------------TGAQGLPGPPGEDGERGD-------------DGEIGPRG 494
             KG RG                G+ GLPG PG  G  GD              G +G  G
Sbjct: 402  SKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPG 461

Query: 495  LPGESGPRGLLGP--------KGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT 546
            +PG  GP+G  G          GPPG+PG PG+ G+ G  G +G+ G +G PG PG  G 
Sbjct: 462  IPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGL 521

Query: 547  PGTQGLPGPQGAIGPHGEKG----PQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSG 602
            PG  G PG QG  G  GEKG    P+G+ G+PG PG  G PG  G +G PGT G +G  G
Sbjct: 522  PGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPG 581

Query: 603  PQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF--KGDIGVKGDRGEVGVPGSRGE 660
            P+G L   G +G +G  G  G  G  G  G  G PG+  +G+ G++G +G  G PG  GE
Sbjct: 582  PKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGE 641

Query: 661  DGPEG----------PKGRTGPTGDPGP---PGLMGEKGKLGVPGLPG-----------Y 696
             GP G          P G  GP G PGP   PG+ G  GK G PGLPG           +
Sbjct: 642  AGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF 701

Query: 697  PGRQGPKGSLGFPGFPGA---SGEKGARGLSGKSGPRGERG------PTGPR--GQRGPR 745
            PG  GPKG  GFPG  G+    G+ G  GL GK G  G +G      P GP   G  G R
Sbjct: 702  PGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGER 761

Query: 746  GATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK--------DGLPG 797
            G +G+ G  G  G  G  G PG  GL GP+G  G PGP G  GPPG+         GLPG
Sbjct: 762  GNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPG 821

Query: 798  HPGQRGEVGFQGKTGPPGPPGVVG--PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGK 855
              G +G+ G +GKTGP G PG+ G    G  GETG  G  GH G  GP G++G PG    
Sbjct: 822  LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPG---- 877

Query: 856  EGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGA 915
                 +PG  G PG+DG  G+ GFPG  G PG  G PG  G  G  G PG  G  G  GA
Sbjct: 878  -----NPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932

Query: 916  AGSGGPIGPPGRP------GPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP 969
             G  G  G PG        G +G PG  G  G PGEKG  G  G  G++G  GLPGPAGP
Sbjct: 933  KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992

Query: 970  PGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGH 1029
            PG  G+ G  G  G+PG +G  G+ G  G PG  G  G +G PG AG  G PG  G QG 
Sbjct: 993  PGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGD 1052

Query: 1030 FGAKG-DEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADG 1088
             G  G  EGTR   GPPGP G  GLPG  G+KGE      MG PGPPG  GPAGP GA G
Sbjct: 1053 KGEPGYSEGTRP--GPPGPTGDPGLPGDMGKKGE------MGQPGPPGHLGPAGPEGAPG 1104

Query: 1089 PQGPPGGVGNLGPPGEKG---------EPGESGSPGIQGEPGVKGPRGERGEKGESGQPG 1139
              G PG  G  GP G+ G          PG  G PG+ G PG  GP G RG++G  G PG
Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG 1164

Query: 1140 EPG----------PPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGED 1189
              G          PPGP+G  G  G KG+ G  GFPG PG  G  G  G  G  G  G  
Sbjct: 1165 PAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFP 1224

Query: 1190 GEPGQPGS--PGPTGENGPPGPLGKRG---PAGSPGSE--GRQGGKGAKGDPGAIGAPGK 1242
            G PG PG+  PG TG  GPPG  G  G   P G PGS   G +G KG+ G PG  G PG 
Sbjct: 1225 GPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGT 1284

Query: 1243 TGPVGPAGPAGKPGPDGL---------RGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGL 1293
             G +GP G  G PG  GL         +G PG  G++G PG  G  GPPGP+GP G PG+
Sbjct: 1285 AGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGV 1344

Query: 1294 RGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP 1353
            RGD         PG + +I  PG  G       PG  G PG +GE G PG  G +GP GP
Sbjct: 1345 RGD---------PGTLKIISLPGSPGP------PGTPGEPGMQGEPGPPGPPGNLGPCGP 1389

Query: 1354 PGLPGPAGPKGAKGATGPGGPKGEKGVQGPP 1384
             G P   G  G  G  GP G KG KG +G P
Sbjct: 1390 RGKP---GKDGKPGTPGPAGEKGNKGSKGEP 1417



 Score =  724 bits (1868), Expect = 0.0
 Identities = 456/1100 (41%), Positives = 537/1100 (48%), Gaps = 135/1100 (12%)

Query: 218  YESCEQKELECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGE 277
            Y++ ++K  E   G    P   +  R  + P   P     P +  P  + A G  GLKG 
Sbjct: 347  YDTYQEKGDEGTPG----PPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGS 402

Query: 278  KGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGD-------PGERGPPGRAGLP 330
            KGE     PG    G PG  G AG  G PG  G PGP GD       PG+ G PG  G P
Sbjct: 403  KGERG--RPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSP 460

Query: 331  GSDGAPGPPGTSLMLPFRFGSGGGDKG-PVVAAQEAQAQAILQQARLALRGPPGPMGYTG 389
            G  G  GP G   +L  +     G  G P +           +Q    L+G PG  G TG
Sbjct: 461  GIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTG 520

Query: 390  RPGPLGQPGS---PGLKGESGDL----GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMP 442
             PG  G PG+   PGLKGE G+     G  G  G  GL G PG+ G  G  G  G +G+P
Sbjct: 521  LPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLP 580

Query: 443  GDPG---VKGDRGFDGLPGLPGEKGHRGDTGAQGLPG--PPGEDGERGDDGEIGPRGLPG 497
            G  G   + G++G  G PG PG  G  G  G  G PG  P GE G +G  G  G  G PG
Sbjct: 581  GPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPG 640

Query: 498  ESGPRGLLGPK----GPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT---- 549
            E+GPRG L       GPPG PGPPG  G  GP G  GSLG  G+PG PG  G PG     
Sbjct: 641  EAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIG 700

Query: 550  ----------QGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPG--HPGKEGPPGTKGN 597
                      QG PG +G++G  G+ G  G PG PG+PG+ G P    PG  G PG  G 
Sbjct: 701  FPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGE 760

Query: 598  QGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIG--VKGDRGEVGVP 655
            +G SG  G +G PG  G+ G  G  GL G +G+ G+ G PG +G  G  ++G RG  G+P
Sbjct: 761  RGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLP 820

Query: 656  GSRGEDGPEGPKGRTGPTGDPGPPGL--MGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPG 713
            G  G  G +G +G+TGP GDPG PGL   G  G+ G PG+PG+ G  GP G  G+PG PG
Sbjct: 821  GLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPG 880

Query: 714  ASGEKGARGLSGKSGPRGERGPTGPRGQRGP---RGATGKSGAKGTSGGDGPHGPPGERG 770
              G  G  G+ G  G  G  GP GP G  G    RG+ G  G KG  G  G  G  G++G
Sbjct: 881  ILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKG 940

Query: 771  LPGPQ------GPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQG 824
             PGP       G  G PG KG  G PG+ G  G PG  G  G +G  GP GPPG   P+G
Sbjct: 941  NPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPG---PRG 997

Query: 825  AAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERG 884
              G TG  GE G  G PG  G  G+PG+ GK GT G PG  G PG  G  GL+G  GE G
Sbjct: 998  DLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPG 1057

Query: 885  L--------PGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGA 936
                     PG  G PGL G+ G  G  G  G PG  G AG  G  G PG PG  G PG 
Sbjct: 1058 YSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGP 1117

Query: 937  AGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE 996
             G+ G  G KG +GP G   ++GP GLPG  G PG  G  GD+G  G PG  G KG  G 
Sbjct: 1118 HGDLGFKGIKGLLGPPG---IRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGL 1174

Query: 997  -HGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQG--L 1053
               PPGP G  G  G  G  GA G PG  G +G  G  G  G  G  G PGP GL G  +
Sbjct: 1175 LRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAII 1234

Query: 1054 PGPSGEKGETGDVGPMGPPGPPGP--------RGPAGPNGADGPQGPPGGVGNLGPPGEK 1105
            PG +G +G  G  G  G PGPPGP        +G  G  G  GP+GPPG  G++GPPG  
Sbjct: 1235 PGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRL 1294

Query: 1106 GEPGESGSPGIQGEPGVKGPRGERGEKGESG----------------------------- 1136
            G PG  G PG +G+PG +G  G +GEKG  G                             
Sbjct: 1295 GAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKII 1354

Query: 1137 ----QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEP 1192
                 PG PG P            G PG  G PG PGPPG  GP       G RG+ G+ 
Sbjct: 1355 SLPGSPGPPGTP------------GEPGMQGEPGPPGPPGNLGP------CGPRGKPGKD 1396

Query: 1193 GQPGSPGPTGENGPPGPLGK 1212
            G+PG+PGP GE G  G  G+
Sbjct: 1397 GKPGTPGPAGEKGNKGSKGE 1416



 Score =  368 bits (945), Expect = e-101
 Identities = 255/627 (40%), Positives = 279/627 (44%), Gaps = 122/627 (19%)

Query: 915  AAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP---PG 971
            AA  G      G+    G  G  GEKG P   GP G  G+ G  GP GLPGP GP   PG
Sbjct: 26   AASKGCVCKDKGQCFCDGAKGEKGEKGFP---GPPGSPGQKGFTGPEGLPGPQGPKGFPG 82

Query: 972  VAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGE---PGARGPQG 1028
            + G  G KG  G  G  G  G+ G  G PG  GP G VG PG +G+ GE   PG  G  G
Sbjct: 83   LPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLG 142

Query: 1029 HFGAKGDEGTRGFNGPP-----------GPIGLQGLPGPSGEKGETGDVGPMGPPGPP-- 1075
            + G  G  G +G  G P           G  GL G PGP G  G  G  GP+GPPGPP  
Sbjct: 143  YPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGF 202

Query: 1076 -------GPRGP--------------AGPNGADGPQGPPGGV------------------ 1096
                   GPRGP               G  G  GP GPPG V                  
Sbjct: 203  FGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKG 262

Query: 1097 -----GNLGPPGEKGEPGES--------GSPGIQGEP---GVKGPRGERGEKGESGQPGE 1140
                 G  GPPG  G PGES        G PG+QG+P   GV G  G  G KG  G PG 
Sbjct: 263  DKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGL 322

Query: 1141 PGPPGPKGPTGDDGPKGNPGPVGF------PGDPGPPGEGGPRGQDGAKGDRGEDGEPGQ 1194
             G  G KG  GD GP G  GP  +       GD G PG  GPRG  G +G  G  G PG 
Sbjct: 323  MGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGS 382

Query: 1195 PGS--PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA 1252
            PGS  PG  G  G PG  G +G  G PG +      G  G PG  G+PG  G  GP GP 
Sbjct: 383  PGSSRPGLRGAPGWPGLKGSKGERGRPGKD----AMGTPGSPGCAGSPGLPGSPGPPGPP 438

Query: 1253 G----KPGPDGLRGLPGSVGQQGRPGATGQAGP-----------PGPVGPPGLPGLRGDA 1297
            G    + GP G  GLPG +G  G PG  G  G            PGP G PGLPGL G  
Sbjct: 439  GDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVK 498

Query: 1298 GAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGE----------MGIPGASGP 1347
            G  G +G  GL G  G PG  G  G  G PG QG PG KGE          +G+PG  G 
Sbjct: 499  GIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGL 558

Query: 1348 IGPGGPPGLPGPAGPKGAKGATGPGGP---KGEKGVQGPPGHPGPPGEVIQPLPIQMPKK 1404
             G  G  GL G  G  G KG  GP G     GEKG QGPPG PG PG    P P      
Sbjct: 559  RGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPG---SPGPAGPAGP 615

Query: 1405 TRRSVDGSRLMQEDEAIPTGGAPGSPG 1431
                  G   +Q  + +P  GAPG PG
Sbjct: 616  PGYGPQGEPGLQGTQGVP--GAPGPPG 640


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
            sapiens]
          Length = 1494

 Score =  894 bits (2311), Expect = 0.0
 Identities = 580/1363 (42%), Positives = 670/1363 (49%), Gaps = 260/1363 (19%)

Query: 270  GPRGLKGEKGEPAVL-EPGML----VEGPPGPEGPAG---------------LIGPPGIQ 309
            G +G KGEKG P     PG       EG PGP+GP G               + G PG  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 310  GNPGPVGDPGERGPPGRAGLPGSDGA------PGPPGTSLMLPFRFGSGG--GDKGPVVA 361
            G+PG  G PG  GP G  G+PG  G+      PG PGT L  P   G+ G  G KG    
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGT-LGYPGIPGAAGLKGQKGAPAK 161

Query: 362  AQEAQAQAILQQARLALRGPPGPMGYTGRPG---PLGQPGSPGLKGESGDLGPQGP---- 414
             ++ +  A   +    L G PGP G  G PG   P+G PG PG  G  G +GP+GP    
Sbjct: 162  EEDIELDA---KGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHM 218

Query: 415  ----------RGPQGLTGPPGKAGR--------------RGRAGADGA------------ 438
                      RG +GLTGPPG  G               +G  G  GA            
Sbjct: 219  GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGL 278

Query: 439  --------RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI 490
                    +G PGDPG++G  G DG+PG PG +G +G+   +G PG  GEDG +G  G+I
Sbjct: 279  PGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN---RGFPGLMGEDGIKGQKGDI 335

Query: 491  GP------------------RGLPGESGPRGLLGPKGP---PGIPGPPG-----VRGMDG 524
            GP                   G PG  GPRG  GP+GP   PG+PG PG     +RG  G
Sbjct: 336  GPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPG 395

Query: 525  PQGPKGSLGPQGEPGP-----PGQQGTPGTQGLPGPQGAIGPHGE----KGPQGKPGLPG 575
              G KGS G +G PG      PG  G  G+ GLPG  G  GP G+    KGP G  GLPG
Sbjct: 396  WPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPG 455

Query: 576  MPGSDGPPGHPGKEGPPGTKGNQGP--SGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGE 633
              GS G PG  G +G PG    Q P   GP G  G PG  GVKG+ G +G  G KG  G 
Sbjct: 456  YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515

Query: 634  DG---------FPGFKGDIGVKGDRGE-------VGVPGSRGEDGPEGPKGRTGPTGDPG 677
             G         FPG +GD G+KG++GE       VGVPG  G  G  G KG  G  G PG
Sbjct: 516  PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575

Query: 678  PPGLMGEKGKL------------GVPGLPGYPGRQGPKGSLGF-----PGFPGASGEKGA 720
              GL G KG+L            G PG PG PG  GP G  G+     PG  G  G  GA
Sbjct: 576  VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635

Query: 721  RGLSGKSGPRGER----------GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG 770
             G  G++GPRGE           GP GP G  GP+G  G  G+ G  G  G  GP GE G
Sbjct: 636  PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPG 695

Query: 771  LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP--------PGVVGP 822
            +PG   P G PGPKG  G PG  G  G PG+ GE G  GK G PG         PG  G 
Sbjct: 696  IPGIGFP-GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGT 754

Query: 823  QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE 882
             G  GE G  GE G  G PG PG  G PG  G +G +GDPG PG PG+ GP G R   G 
Sbjct: 755  PGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPG-RCIEGP 813

Query: 883  RGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSG--GPIGPPGRPGPQGPPGAAGEK 940
            RG  G  G  GLKG +G  G  GP G PG  G   SG  G  G PG PG QG  G  G++
Sbjct: 814  RGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQR 873

Query: 941  GVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPG------QKGTKGNK 994
            G PG  G +GP G DGV G +G PG  GPPG  G  G  G+ G PG      Q+GT G K
Sbjct: 874  GYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAK 933

Query: 995  GEHGPPGPPGP------IGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPI 1048
            GE G  G PGP      IG  G+PG  G  G PG            ++G RG  G PG  
Sbjct: 934  GEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPG------------EKGNRGVPGMPGLK 981

Query: 1049 GLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP 1108
            GL+GLPGP+G  G  GD+G  G PG PG RG  G  G  G  G  G  G LG PG  G P
Sbjct: 982  GLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRP 1041

Query: 1109 GESGSPGIQGE-----------PGVKGPRGERG---EKGESGQPGEPGPPGPKGPTGDDG 1154
            G  G  G+QG+           PG  GP G+ G   + G+ G+ G+PGPPG  GP G +G
Sbjct: 1042 GLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101

Query: 1155 PKGNPGPVGFPGDPGPPGEGGPRGQDGAKGD---RGEDGEPGQPGSPGPTG------ENG 1205
              G+PG  G PG PGP G+ G +G  G  G    RG  G PG PGSPGP G       +G
Sbjct: 1102 APGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDG 1161

Query: 1206 PPGPLGKRGPAG----SPGSEGRQGGKGAKGD---------PGAIGAPGKTGPVGPAGPA 1252
             PGP G++G  G     PG  G  G +GAKGD         PG  GA G  GP GP G  
Sbjct: 1162 IPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIE 1221

Query: 1253 GKPGPDGLRG--LPGSVGQQGRPGATGQAGPPGPVGPPG--LPGLRGDAGAKGE---KGH 1305
            G PGP GL G  +PG  G +G PG+ G  G PGP GPPG  + G++GD G+ G    KG 
Sbjct: 1222 GFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP 1281

Query: 1306 PGLIGLIGPPGEQGEKGDRGLPGP------QGSPGQKGEMGIPGASGPIGPGGPPGLPGP 1359
            PG  G +GPPG  G  G  GLPGP      QG PG KGE G PG  G IGP GP G  GP
Sbjct: 1282 PGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGP 1341

Query: 1360 AGPKG---------AKGATGPGGPKGEKGVQGPPGHPGPPGEV 1393
             G +G           G+ GP G  GE G+QG PG PGPPG +
Sbjct: 1342 PGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNL 1384



 Score =  874 bits (2257), Expect = 0.0
 Identities = 551/1298 (42%), Positives = 639/1298 (49%), Gaps = 201/1298 (15%)

Query: 262  EPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGER 321
            +P    A GP+GL G  G P          GP GP GP G  G PG  G  GP G  GER
Sbjct: 172  DPGLPGAPGPQGLPGPPGFP----------GPVGPPGPPGFFGFPGAMGPRGPKGHMGER 221

Query: 322  --GPPGRAGLPGSDGAPGPPGTSLML----PFRFGSGG--GDKGPVVAAQEAQAQAILQQ 373
              G  G  G+ G  G PGPPGT ++       R    G  GDKG +          +  +
Sbjct: 222  VIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGE 281

Query: 374  ARLALRGPPGPMGYTGRPGPLGQPGSPG------------------LKGESGDLGPQGPR 415
            +  + +G PG  G  G+PG  G PG PG                  +KG+ GD+GP G R
Sbjct: 282  SYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFR 341

Query: 416  GP------------QGLTGPPGKAGRRGRAGADGARGMPGDPGVK--GDRGFDGLPGLPG 461
            GP            +G  GPPG  G RG  G  G  G+PG PG    G RG  G PGL G
Sbjct: 342  GPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKG 401

Query: 462  EKGHRGD--------------TGAQGLPGPPGEDGERGD-------------DGEIGPRG 494
             KG RG                G+ GLPG PG  G  GD              G +G  G
Sbjct: 402  SKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPG 461

Query: 495  LPGESGPRGLLGP--------KGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT 546
            +PG  GP+G  G          GPPG+PG PG+ G+ G  G +G+ G +G PG PG  G 
Sbjct: 462  IPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGL 521

Query: 547  PGTQGLPGPQGAIGPHGEKG----PQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSG 602
            PG  G PG QG  G  GEKG    P+G+ G+PG PG  G PG  G +G PGT G +G  G
Sbjct: 522  PGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPG 581

Query: 603  PQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF--KGDIGVKGDRGEVGVPGSRGE 660
            P+G L   G +G +G  G  G  G  G  G  G PG+  +G+ G++G +G  G PG  GE
Sbjct: 582  PKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGE 641

Query: 661  DGPEG----------PKGRTGPTGDPGP---PGLMGEKGKLGVPGLPG-----------Y 696
             GP G          P G  GP G PGP   PG+ G  GK G PGLPG           +
Sbjct: 642  AGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF 701

Query: 697  PGRQGPKGSLGFPGFPGA---SGEKGARGLSGKSGPRGERG------PTGPR--GQRGPR 745
            PG  GPKG  GFPG  G+    G+ G  GL GK G  G +G      P GP   G  G R
Sbjct: 702  PGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGER 761

Query: 746  GATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK--------DGLPG 797
            G +G+ G  G  G  G  G PG  GL GP+G  G PGP G  GPPG+         GLPG
Sbjct: 762  GNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPG 821

Query: 798  HPGQRGEVGFQGKTGPPGPPGVVG--PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGK 855
              G +G+ G +GKTGP G PG+ G    G  GETG  G  GH G  GP G++G PG    
Sbjct: 822  LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPG---- 877

Query: 856  EGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGA 915
                 +PG  G PG+DG  G+ GFPG  G PG  G PG  G  G  G PG  G  G  GA
Sbjct: 878  -----NPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932

Query: 916  AGSGGPIGPPGRP------GPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP 969
             G  G  G PG        G +G PG  G  G PGEKG  G  G  G++G  GLPGPAGP
Sbjct: 933  KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992

Query: 970  PGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGH 1029
            PG  G+ G  G  G+PG +G  G+ G  G PG  G  G +G PG AG  G PG  G QG 
Sbjct: 993  PGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGD 1052

Query: 1030 FGAKG-DEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADG 1088
             G  G  EGTR   GPPGP G  GLPG  G+KGE      MG PGPPG  GPAGP GA G
Sbjct: 1053 KGEPGYSEGTRP--GPPGPTGDPGLPGDMGKKGE------MGQPGPPGHLGPAGPEGAPG 1104

Query: 1089 PQGPPGGVGNLGPPGEKG---------EPGESGSPGIQGEPGVKGPRGERGEKGESGQPG 1139
              G PG  G  GP G+ G          PG  G PG+ G PG  GP G RG++G  G PG
Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG 1164

Query: 1140 EPG----------PPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGED 1189
              G          PPGP+G  G  G KG+ G  GFPG PG  G  G  G  G  G  G  
Sbjct: 1165 PAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFP 1224

Query: 1190 GEPGQPGS--PGPTGENGPPGPLGKRG---PAGSPGSE--GRQGGKGAKGDPGAIGAPGK 1242
            G PG PG+  PG TG  GPPG  G  G   P G PGS   G +G KG+ G PG  G PG 
Sbjct: 1225 GPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGT 1284

Query: 1243 TGPVGPAGPAGKPGPDGL---------RGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGL 1293
             G +GP G  G PG  GL         +G PG  G++G PG  G  GPPGP+GP G PG+
Sbjct: 1285 AGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGV 1344

Query: 1294 RGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP 1353
            RGD G       PG  G  G PGE G +G+ G PGP G+ G  G  G PG        G 
Sbjct: 1345 RGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKD------GK 1398

Query: 1354 PGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1391
            PG PGPAG KG KG+ G  GP G  G+ G  G  G  G
Sbjct: 1399 PGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSG 1436



 Score =  831 bits (2147), Expect = 0.0
 Identities = 510/1154 (44%), Positives = 581/1154 (50%), Gaps = 97/1154 (8%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVE-----------GPPGPEG---PAGLIGPPGI 308
            P      G +G KG+ G P    P    +           GPPGP G   P G  GPPG+
Sbjct: 320  PGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGV 379

Query: 309  QGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLM-LPFRFGSGGGDKGPVVAAQEAQA 367
             G+PG    PG RG PG  GL GS G  G PG   M  P   G  G    P         
Sbjct: 380  PGSPGS-SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPP 438

Query: 368  QAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPR--GPQGLTGPPG 425
              I+ +     +GPPG  G  G  G  G PG  G KGE G L  Q P   GP GL G PG
Sbjct: 439  GDIVFR-----KGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493

Query: 426  KAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGE------KGHRGDT-GAQGLPGPP 478
              G +G  G  GA G+ G PG  G+ G  G PG PG       KG +G+T   +G  G P
Sbjct: 494  LHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVP 553

Query: 479  GEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEP 538
            G+ G RG  G  G  G+PG  G +GL GPKG   + G  G +G  G  G  GS GP G  
Sbjct: 554  GDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPA 613

Query: 539  GPPGQ--QGTPGTQGLPGPQGAIGPHGEKGPQGKPGL----PGMPGSDGPPGHPGKEGPP 592
            GPPG   QG PG QG  G  GA GP GE GP+G+  +    PG PG  GPPGHPG +GPP
Sbjct: 614  GPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPP 673

Query: 593  GTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEV 652
            G  G+ G  G  G    PGP G  G+ GI G  G  G KG+ GFPG KG +G  G  GE 
Sbjct: 674  GIPGSLGKCGDPG---LPGPDGEPGIPGI-GFPGPPGPKGDQGFPGTKGSLGCPGKMGEP 729

Query: 653  GVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFP 712
            G+PG  G  G +G      P G PG PG  GE+G  G  G  G PG  G       PG P
Sbjct: 730  GLPGKPGLPGAKGEPAVAMP-GGPGTPGFPGERGNSGEHGEIGLPGLPG------LPGTP 782

Query: 713  GASGEKGARGLSGKSGPRGERGPTGP--RGQRGPRGATGKSGAKGTSGGDGPHGPPGERG 770
            G  G  G RG  G+ GP GE+GP G    G RG +G  G +G KG  G  G  GP G+ G
Sbjct: 783  GNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPG 842

Query: 771  LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP---------PGVVG 821
            +PG    +GFPG  G PG PG  G  G  GQRG  G  G  GPPG          PG +G
Sbjct: 843  IPGLDR-SGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIG 901

Query: 822  PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP---GKDGPAGLRG 878
            P G  G  G  G+RG PG PG  G++G PG  G++G KG+PGP       G  G  GL+G
Sbjct: 902  PPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKG 961

Query: 879  FPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAG 938
            F G  G  G  G PG+ G +G  G PGPAG PG RG  GS    G PG PG +G PG+ G
Sbjct: 962  FAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS---TGNPGEPGLRGIPGSMG 1018

Query: 939  EKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE--------DGDKGEVGDPGQKGT 990
              G+PG KG  G  G  G  G  GLPG  G  G  GE         G  G  GDPG  G 
Sbjct: 1019 NMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGD 1078

Query: 991  KGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP---GP 1047
             G KGE G PGPPG +GP G  GA G+ G PG  G  G  G  G +G +G  GPP   GP
Sbjct: 1079 MGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGP 1138

Query: 1048 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1107
             GL G PG  G  G  GD G  G PGP G +G  G   A     PPG  GN G  G KG+
Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRA-----PPGPRGNPGAQGAKGD 1193

Query: 1108 PGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGP--KGPTGDDGPKGNPGPVGFP 1165
             G  G PG+ G  G  G  G RG  G  G PG PG PG    G TG+ GP G+ G  G P
Sbjct: 1194 RGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAP 1253

Query: 1166 GDPGPPGEG--GPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEG 1223
            G PGPPG    G +G  G+ G  G  G PG  G  GP G  G PG  G  GP G PG +G
Sbjct: 1254 GPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313

Query: 1224 RQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDG---LRGLPGSVGQQGRPGATGQAG 1280
              G KG KG+PG +G+ G  GP+GP GP G  G  G   +  LPGS G  G PG  G  G
Sbjct: 1314 FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373

Query: 1281 PPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMG 1340
             PGP GPPG  G  G  G  G+ G P   G  GP GE+G KG +G PGP GS       G
Sbjct: 1374 EPGPPGPPGNLGPCGPRGKPGKDGKP---GTPGPAGEKGNKGSKGEPGPAGSD------G 1424

Query: 1341 IPGASGPIGPGGPP 1354
            +PG  G  G  G P
Sbjct: 1425 LPGLKGKRGDSGSP 1438



 Score =  804 bits (2077), Expect = 0.0
 Identities = 516/1242 (41%), Positives = 594/1242 (47%), Gaps = 217/1242 (17%)

Query: 380  GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGAR 439
            G  G  G  G PGP G PG  G  G  G  GPQGP+G  GL G  G  G RG +G  G  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 440  GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 499
            G PG PG  G+ G  GL G+PG  G +G+ G  GLPG  G  G  G  G  G +G P + 
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 500  GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQG-- 557
                L   KG PG+PG PG +G+ GP G  G +GP   PGPPG  G PG  G  GP+G  
Sbjct: 163  EDIEL-DAKGDPGLPGAPGPQGLPGPPGFPGPVGP---PGPPGFFGFPGAMGPRGPKGHM 218

Query: 558  ---AIGPHGEKGPQGKPGLPGMPGS-----DGPPGHPGKEGPPGTKGNQGPSGPQGPLGY 609
                IG  GE+G +G  G PG PG+      GP      +G  G KG  G  GP GP G 
Sbjct: 219  GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGL 278

Query: 610  PGP--------------RGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVP 655
            PG               +G  G DG+ G  G +G KG  GFPG  G+ G+KG +G++G P
Sbjct: 279  PGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPP 338

Query: 656  GSRGED---------------GPEGPKGRTGPTGDPGPPGLMGEKG--KLGVPGLPGYPG 698
            G RG                 GP GP+G  GP G  GPPG+ G  G  + G+ G PG+PG
Sbjct: 339  GFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPG 398

Query: 699  RQGPKG--------SLGFPGFPGASGEKGARGLSGKSGPRGE----RGPTGPRGQRGPRG 746
             +G KG        ++G PG PG +G  G  G  G  GP G+    +GP G  G  G  G
Sbjct: 399  LKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLG 458

Query: 747  ATGKSGAKGTSGGDG------PH--GPPGERGLPGPQGPNGFPGP------KGPPGPPGK 792
            + G  G  G  G  G      P+  GPPG  GLPG  G  G PG       KG PG PG 
Sbjct: 459  SPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGN 518

Query: 793  DGLPGHPGQRGEVGFQGKTGPPG----PPGVVGPQGAAGETGPMGERGHPGPPGPPGEQG 848
             GLPG PG  G  G  G  G  G    P G VG  G  G  G  G +G  G PG PG +G
Sbjct: 519  TGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKG 578

Query: 849  LPGT------AGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSG 902
            LPG       +G++G +G PG PG+PG  GPAG  G PG     G  G PGL+G +G  G
Sbjct: 579  LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY----GPQGEPGLQGTQGVPG 634

Query: 903  PPGPAGSPGERG-------AAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD 955
             PGP G  G RG         G  GP GPPG PGPQGPPG  G  G  G+ G  GP G  
Sbjct: 635  APGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEP 694

Query: 956  GVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGT------------------------- 990
            G+ G +G PGP GP G  G  G KG +G PG+ G                          
Sbjct: 695  GIPG-IGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPG 753

Query: 991  -------KGNKGEHGP---------PGPPG------PIGPVGQPGAAGADGEPG------ 1022
                   +GN GEHG          PG PG      P G  GQPG  G  G PG      
Sbjct: 754  TPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGP 813

Query: 1023 --ARGPQGHFGAKGDEGTRGFNGPPGPIGLQGL-----------PGPSGEKGETGDVGPM 1069
              A+G  G  G KG +G RG  GP G  G+ GL           PG  G +GE G +G  
Sbjct: 814  RGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQR 873

Query: 1070 GPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGER 1129
            G PG PG  GP G +G  G  G PG +G  GPPG  G PG+ GSPGI   PGVKG RG  
Sbjct: 874  GYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGI---PGVKGQRGTP 930

Query: 1130 GEKGESGQPGEPGP------------PGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPR 1177
            G KGE G  G PGP            PG KG  G+ G KGN G  G PG  G  G  GP 
Sbjct: 931  GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPA 990

Query: 1178 GQDGAKGDRGEDGEPGQPGS---PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDP 1234
            G  G +GD G  G PG+PG    PG  G  G PG  GKRG  G PG  GR G  G  G  
Sbjct: 991  GPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQ 1050

Query: 1235 GAIGAPGKTGPV--GPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG 1292
            G  G PG +     GP GP G PG  G  G  G +GQ G PG  G AGP G  G PG PG
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 1293 LRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPG---PQGSPGQKGEMGIPGASGPIG 1349
            L G  G  G+ G  G+ GL+GPPG +G  G  G PG   P G  G +G  GIPG +G  G
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170

Query: 1350 -------PGGPPGLPGPAGPK------------GAKGATGPGGPKGEKGVQGPPGHPGPP 1390
                   P GP G PG  G K            G KGA G  GP+G  G++G PG PG P
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 1391 GEVIQPLPIQMPKKT-RRSVDGSRLMQEDEAIPTGGAPGSPG 1431
            G +I       P +T  R   GSR         + GAPG PG
Sbjct: 1231 GAII-------PGQTGNRGPPGSR--------GSPGAPGPPG 1257



 Score =  751 bits (1940), Expect = 0.0
 Identities = 466/1111 (41%), Positives = 548/1111 (49%), Gaps = 114/1111 (10%)

Query: 218  YESCEQKELECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGE 277
            Y++ ++K  E   G    P   +  R  + P   P     P +  P  + A G  GLKG 
Sbjct: 347  YDTYQEKGDEGTPG----PPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGS 402

Query: 278  KGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGD-------PGERGPPGRAGLP 330
            KGE     PG    G PG  G AG  G PG  G PGP GD       PG+ G PG  G P
Sbjct: 403  KGERG--RPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSP 460

Query: 331  GSDGAPGPPGTSLMLPFRFGSGGGDKG-PVVAAQEAQAQAILQQARLALRGPPGPMGYTG 389
            G  G  GP G   +L  +     G  G P +           +Q    L+G PG  G TG
Sbjct: 461  GIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTG 520

Query: 390  RPGPLGQPGS---PGLKGESGDL----GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMP 442
             PG  G PG+   PGLKGE G+     G  G  G  GL G PG+ G  G  G  G +G+P
Sbjct: 521  LPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLP 580

Query: 443  GDPG---VKGDRGFDGLPGLPGEKGHRGDTGAQGLPG--PPGEDGERGDDGEIGPRGLPG 497
            G  G   + G++G  G PG PG  G  G  G  G PG  P GE G +G  G  G  G PG
Sbjct: 581  GPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPG 640

Query: 498  ESGPRGLLGPK----GPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT---- 549
            E+GPRG L       GPPG PGPPG  G  GP G  GSLG  G+PG PG  G PG     
Sbjct: 641  EAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIG 700

Query: 550  ----------QGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPG--HPGKEGPPGTKGN 597
                      QG PG +G++G  G+ G  G PG PG+PG+ G P    PG  G PG  G 
Sbjct: 701  FPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGE 760

Query: 598  QGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIG--VKGDRGEVGVP 655
            +G SG  G +G PG  G+ G  G  GL G +G+ G+ G PG +G  G  ++G RG  G+P
Sbjct: 761  RGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLP 820

Query: 656  GSRGEDGPEGPKGRTGPTGDPGPPGL--MGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPG 713
            G  G  G +G +G+TGP GDPG PGL   G  G+ G PG+PG+ G  GP G  G+PG PG
Sbjct: 821  GLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPG 880

Query: 714  ASGEKGARGLSGKSGPRGERGPTGPRGQRGP---RGATGKSGAKGTSGGDGPHGPPGERG 770
              G  G  G+ G  G  G  GP GP G  G    RG+ G  G KG  G  G  G  G++G
Sbjct: 881  ILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKG 940

Query: 771  LPGPQ------GPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQG 824
             PGP       G  G PG KG  G PG+ G  G PG  G  G +G  GP GPPG   P+G
Sbjct: 941  NPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPG---PRG 997

Query: 825  AAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERG 884
              G TG  GE G  G PG  G  G+PG+ GK GT G PG  G PG  G  GL+G  GE G
Sbjct: 998  DLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPG 1057

Query: 885  L--------PGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGA 936
                     PG  G PGL G+ G  G  G  G PG  G AG  G  G PG PG  G PG 
Sbjct: 1058 YSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGP 1117

Query: 937  AGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE 996
             G+ G  G KG +GP G   ++GP GLPG  G PG  G  GD+G  G PG  G KG  G 
Sbjct: 1118 HGDLGFKGIKGLLGPPG---IRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGL 1174

Query: 997  -HGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQG--L 1053
               PPGP G  G  G  G  GA G PG  G +G  G  G  G  G  G PGP GL G  +
Sbjct: 1175 LRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAII 1234

Query: 1054 PGPSGEKGETGDVGPMGPPGPPGP--------RGPAGPNGADGPQGPPGGVGNLGPPGEK 1105
            PG +G +G  G  G  G PGPPGP        +G  G  G  GP+GPPG  G++GPPG  
Sbjct: 1235 PGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRL 1294

Query: 1106 GEPGESGSPGIQGEPGVKGPRGERGEKGESG----------------------------- 1136
            G PG  G PG +G+PG +G  G +GEKG  G                             
Sbjct: 1295 GAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKII 1354

Query: 1137 -QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQP 1195
              PG PGPPG  G  G  G  G PGP G  G  GP G+ G  G+ G  G  GE G  G  
Sbjct: 1355 SLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSK 1414

Query: 1196 GSPGPTGENGPPGPLGKRGPAGSPGSEGRQG 1226
            G PGP G +G PG  GKRG +GSP +   +G
Sbjct: 1415 GEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445



 Score =  617 bits (1592), Expect = e-176
 Identities = 390/938 (41%), Positives = 464/938 (49%), Gaps = 175/938 (18%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVLE--------PGMLVEGPPGPEGPAGLIGPPGIQGNPGP 314
            P    A G  GLKGEKGE    E        PG+   G PG +G  G+ G PG++G PGP
Sbjct: 525  PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGL--RGQPGRKGLDGIPGTPGVKGLPGP 582

Query: 315  VGD------PGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--------GDKGPVV 360
             G+       G++GPPG  G PGS G  GP G     P  +G  G        G  G   
Sbjct: 583  KGELALSGEKGDQGPPGDPGSPGSPGPAGPAG-----PPGYGPQGEPGLQGTQGVPGAPG 637

Query: 361  AAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLG---------- 410
               EA  +  L  +   + GPPGP G  G PGP G PG PG  G+ GD G          
Sbjct: 638  PPGEAGPRGELSVST-PVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGI 696

Query: 411  -------PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDR-----GFDGLPG 458
                   P GP+G QG  G  G  G  G+ G  G  G PG PG KG+      G  G PG
Sbjct: 697  PGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPG 756

Query: 459  LPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGP-----KGPPGI 513
             PGE+G+ G+ G  GLPG PG  G  G++G  GPRG PG+ GP G  GP     +GP G 
Sbjct: 757  FPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGA 816

Query: 514  PGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQ-----GTPGTQGLPGPQGAIGPHGEKGPQ 568
             G PG+ G+ G QG +G  GP+G+PG PG       G  G+ G+PG QG +GP G++G  
Sbjct: 817  QGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876

Query: 569  GKPGLPGMPGSDGP---PGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLK 625
            G PG+ G PG DG     G PG  GPPG  GN G  G +G  G PG +G +G  G +G +
Sbjct: 877  GNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQ 936

Query: 626  GHKG------------EKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPT 673
            G KG            +KGE G  GF G+ G KG+RG  G+PG +G  G  GP G  GP 
Sbjct: 937  GDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPR 996

Query: 674  GDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER 733
            GD G  G  GE G  G+PG  G  G  G KG  G  GFPG +G  G  G+ G  G +GE 
Sbjct: 997  GDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056

Query: 734  GPTGPRGQR-GPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK 792
            G +   G R GP G TG  G  G  G        GE G PGP G  G  GP+G PG PG 
Sbjct: 1057 GYS--EGTRPGPPGPTGDPGLPGDMG------KKGEMGQPGPPGHLGPAGPEGAPGSPGS 1108

Query: 793  DGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAG---ETGPMGERGH------PGPPG- 842
             GLPG PG  G++GF+G  G  GPPG+ GP G  G     GPMG RG       PGP G 
Sbjct: 1109 PGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE 1168

Query: 843  ---------PPGEQGLPGTAGKEGTKGDPGPPGAPGKDG---------PAGLRGFPGERG 884
                     PPG +G PG  G +G +G PG PG PG+ G         P G+ GFPG  G
Sbjct: 1169 KGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPG 1228

Query: 885  LPGTA--------GGPGLKGNEGPSGPPGPAGS--------------PGERGAAGSGGPI 922
            LPG          G PG +G+ G  GPPGP GS              PG +G  G+ G +
Sbjct: 1229 LPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDM 1288

Query: 923  GPPGR---------PGPQGPPGAAGEKGVPGEKG------------PIGPTGRDGVQGPV 961
            GPPGR         PGP+G PG  G  GV GEKG            PIGP G  GV+G  
Sbjct: 1289 GPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDP 1348

Query: 962  G------LPGPAGPPGVAGEDGDKGEVGDPGQKGT------KGNKGEHGPPGPPGPIGPV 1009
            G      LPG  GPPG  GE G +GE G PG  G       +G  G+ G PG PGP G  
Sbjct: 1349 GTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEK 1408

Query: 1010 G------QPGAAGADGEPGARGPQGHFGAKGDEGTRGF 1041
            G      +PG AG+DG PG +G +G  G+     TRGF
Sbjct: 1409 GNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGF 1446



 Score =  368 bits (945), Expect = e-101
 Identities = 255/627 (40%), Positives = 279/627 (44%), Gaps = 122/627 (19%)

Query: 915  AAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP---PG 971
            AA  G      G+    G  G  GEKG P   GP G  G+ G  GP GLPGP GP   PG
Sbjct: 26   AASKGCVCKDKGQCFCDGAKGEKGEKGFP---GPPGSPGQKGFTGPEGLPGPQGPKGFPG 82

Query: 972  VAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGE---PGARGPQG 1028
            + G  G KG  G  G  G  G+ G  G PG  GP G VG PG +G+ GE   PG  G  G
Sbjct: 83   LPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLG 142

Query: 1029 HFGAKGDEGTRGFNGPP-----------GPIGLQGLPGPSGEKGETGDVGPMGPPGPP-- 1075
            + G  G  G +G  G P           G  GL G PGP G  G  G  GP+GPPGPP  
Sbjct: 143  YPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGF 202

Query: 1076 -------GPRGP--------------AGPNGADGPQGPPGGV------------------ 1096
                   GPRGP               G  G  GP GPPG V                  
Sbjct: 203  FGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKG 262

Query: 1097 -----GNLGPPGEKGEPGES--------GSPGIQGEP---GVKGPRGERGEKGESGQPGE 1140
                 G  GPPG  G PGES        G PG+QG+P   GV G  G  G KG  G PG 
Sbjct: 263  DKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGL 322

Query: 1141 PGPPGPKGPTGDDGPKGNPGPVGF------PGDPGPPGEGGPRGQDGAKGDRGEDGEPGQ 1194
             G  G KG  GD GP G  GP  +       GD G PG  GPRG  G +G  G  G PG 
Sbjct: 323  MGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGS 382

Query: 1195 PGS--PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA 1252
            PGS  PG  G  G PG  G +G  G PG +      G  G PG  G+PG  G  GP GP 
Sbjct: 383  PGSSRPGLRGAPGWPGLKGSKGERGRPGKD----AMGTPGSPGCAGSPGLPGSPGPPGPP 438

Query: 1253 G----KPGPDGLRGLPGSVGQQGRPGATGQAGP-----------PGPVGPPGLPGLRGDA 1297
            G    + GP G  GLPG +G  G PG  G  G            PGP G PGLPGL G  
Sbjct: 439  GDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVK 498

Query: 1298 GAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGE----------MGIPGASGP 1347
            G  G +G  GL G  G PG  G  G  G PG QG PG KGE          +G+PG  G 
Sbjct: 499  GIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGL 558

Query: 1348 IGPGGPPGLPGPAGPKGAKGATGPGGP---KGEKGVQGPPGHPGPPGEVIQPLPIQMPKK 1404
             G  G  GL G  G  G KG  GP G     GEKG QGPPG PG PG    P P      
Sbjct: 559  RGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPG---SPGPAGPAGP 615

Query: 1405 TRRSVDGSRLMQEDEAIPTGGAPGSPG 1431
                  G   +Q  + +P  GAPG PG
Sbjct: 616  PGYGPQGEPGLQGTQGVP--GAPGPPG 640



 Score =  149 bits (377), Expect = 2e-35
 Identities = 96/253 (37%), Positives = 121/253 (47%), Gaps = 38/253 (15%)

Query: 270  GPRGLKGEKGEPAVLEPGMLV------EGPPGPEGPAGLIGPPG--------IQGNPGPV 315
            GP G++G  G P +  PG ++       GPPG  G  G  GPPG        I+G+ G +
Sbjct: 1216 GPTGIEGFPGPPGL--PGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSM 1273

Query: 316  GDPGERGPPGRAG---LPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQ 372
            G PG +GPPG AG    PG  GAPG PG    LP   G  G    P V  +         
Sbjct: 1274 GHPGPKGPPGTAGDMGPPGRLGAPGTPG----LPGPRGDPGFQGFPGVKGE--------- 1320

Query: 373  QARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGR 432
                  +G PG +G  G PGP+G  G PG++G+ G L      G  G  G PG+ G +G 
Sbjct: 1321 ------KGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGE 1374

Query: 433  AGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGP 492
             G  G  G  G  G +G  G DG PG PG  G +G+ G++G PGP G DG  G  G+ G 
Sbjct: 1375 PGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGD 1434

Query: 493  RGLPGESGPRGLL 505
             G P     RG +
Sbjct: 1435 SGSPATWTTRGFV 1447


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1637

 Score =  894 bits (2311), Expect = 0.0
 Identities = 580/1363 (42%), Positives = 670/1363 (49%), Gaps = 260/1363 (19%)

Query: 270  GPRGLKGEKGEPAVL-EPGML----VEGPPGPEGPAG---------------LIGPPGIQ 309
            G +G KGEKG P     PG       EG PGP+GP G               + G PG  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 310  GNPGPVGDPGERGPPGRAGLPGSDGA------PGPPGTSLMLPFRFGSGG--GDKGPVVA 361
            G+PG  G PG  GP G  G+PG  G+      PG PGT L  P   G+ G  G KG    
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGT-LGYPGIPGAAGLKGQKGAPAK 161

Query: 362  AQEAQAQAILQQARLALRGPPGPMGYTGRPG---PLGQPGSPGLKGESGDLGPQGP---- 414
             ++ +  A   +    L G PGP G  G PG   P+G PG PG  G  G +GP+GP    
Sbjct: 162  EEDIELDA---KGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHM 218

Query: 415  ----------RGPQGLTGPPGKAGR--------------RGRAGADGA------------ 438
                      RG +GLTGPPG  G               +G  G  GA            
Sbjct: 219  GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGL 278

Query: 439  --------RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI 490
                    +G PGDPG++G  G DG+PG PG +G +G+   +G PG  GEDG +G  G+I
Sbjct: 279  PGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN---RGFPGLMGEDGIKGQKGDI 335

Query: 491  GP------------------RGLPGESGPRGLLGPKGP---PGIPGPPG-----VRGMDG 524
            GP                   G PG  GPRG  GP+GP   PG+PG PG     +RG  G
Sbjct: 336  GPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPG 395

Query: 525  PQGPKGSLGPQGEPGP-----PGQQGTPGTQGLPGPQGAIGPHGE----KGPQGKPGLPG 575
              G KGS G +G PG      PG  G  G+ GLPG  G  GP G+    KGP G  GLPG
Sbjct: 396  WPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPG 455

Query: 576  MPGSDGPPGHPGKEGPPGTKGNQGP--SGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGE 633
              GS G PG  G +G PG    Q P   GP G  G PG  GVKG+ G +G  G KG  G 
Sbjct: 456  YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515

Query: 634  DG---------FPGFKGDIGVKGDRGE-------VGVPGSRGEDGPEGPKGRTGPTGDPG 677
             G         FPG +GD G+KG++GE       VGVPG  G  G  G KG  G  G PG
Sbjct: 516  PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575

Query: 678  PPGLMGEKGKL------------GVPGLPGYPGRQGPKGSLGF-----PGFPGASGEKGA 720
              GL G KG+L            G PG PG PG  GP G  G+     PG  G  G  GA
Sbjct: 576  VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635

Query: 721  RGLSGKSGPRGER----------GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG 770
             G  G++GPRGE           GP GP G  GP+G  G  G+ G  G  G  GP GE G
Sbjct: 636  PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPG 695

Query: 771  LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP--------PGVVGP 822
            +PG   P G PGPKG  G PG  G  G PG+ GE G  GK G PG         PG  G 
Sbjct: 696  IPGIGFP-GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGT 754

Query: 823  QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE 882
             G  GE G  GE G  G PG PG  G PG  G +G +GDPG PG PG+ GP G R   G 
Sbjct: 755  PGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPG-RCIEGP 813

Query: 883  RGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSG--GPIGPPGRPGPQGPPGAAGEK 940
            RG  G  G  GLKG +G  G  GP G PG  G   SG  G  G PG PG QG  G  G++
Sbjct: 814  RGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQR 873

Query: 941  GVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPG------QKGTKGNK 994
            G PG  G +GP G DGV G +G PG  GPPG  G  G  G+ G PG      Q+GT G K
Sbjct: 874  GYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAK 933

Query: 995  GEHGPPGPPGP------IGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPI 1048
            GE G  G PGP      IG  G+PG  G  G PG            ++G RG  G PG  
Sbjct: 934  GEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPG------------EKGNRGVPGMPGLK 981

Query: 1049 GLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP 1108
            GL+GLPGP+G  G  GD+G  G PG PG RG  G  G  G  G  G  G LG PG  G P
Sbjct: 982  GLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRP 1041

Query: 1109 GESGSPGIQGE-----------PGVKGPRGERG---EKGESGQPGEPGPPGPKGPTGDDG 1154
            G  G  G+QG+           PG  GP G+ G   + G+ G+ G+PGPPG  GP G +G
Sbjct: 1042 GLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101

Query: 1155 PKGNPGPVGFPGDPGPPGEGGPRGQDGAKGD---RGEDGEPGQPGSPGPTG------ENG 1205
              G+PG  G PG PGP G+ G +G  G  G    RG  G PG PGSPGP G       +G
Sbjct: 1102 APGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDG 1161

Query: 1206 PPGPLGKRGPAG----SPGSEGRQGGKGAKGD---------PGAIGAPGKTGPVGPAGPA 1252
             PGP G++G  G     PG  G  G +GAKGD         PG  GA G  GP GP G  
Sbjct: 1162 IPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIE 1221

Query: 1253 GKPGPDGLRG--LPGSVGQQGRPGATGQAGPPGPVGPPG--LPGLRGDAGAKGE---KGH 1305
            G PGP GL G  +PG  G +G PG+ G  G PGP GPPG  + G++GD G+ G    KG 
Sbjct: 1222 GFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP 1281

Query: 1306 PGLIGLIGPPGEQGEKGDRGLPGP------QGSPGQKGEMGIPGASGPIGPGGPPGLPGP 1359
            PG  G +GPPG  G  G  GLPGP      QG PG KGE G PG  G IGP GP G  GP
Sbjct: 1282 PGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGP 1341

Query: 1360 AGPKG---------AKGATGPGGPKGEKGVQGPPGHPGPPGEV 1393
             G +G           G+ GP G  GE G+QG PG PGPPG +
Sbjct: 1342 PGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNL 1384



 Score =  874 bits (2257), Expect = 0.0
 Identities = 551/1298 (42%), Positives = 639/1298 (49%), Gaps = 201/1298 (15%)

Query: 262  EPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGER 321
            +P    A GP+GL G  G P          GP GP GP G  G PG  G  GP G  GER
Sbjct: 172  DPGLPGAPGPQGLPGPPGFP----------GPVGPPGPPGFFGFPGAMGPRGPKGHMGER 221

Query: 322  --GPPGRAGLPGSDGAPGPPGTSLML----PFRFGSGG--GDKGPVVAAQEAQAQAILQQ 373
              G  G  G+ G  G PGPPGT ++       R    G  GDKG +          +  +
Sbjct: 222  VIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGE 281

Query: 374  ARLALRGPPGPMGYTGRPGPLGQPGSPG------------------LKGESGDLGPQGPR 415
            +  + +G PG  G  G+PG  G PG PG                  +KG+ GD+GP G R
Sbjct: 282  SYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFR 341

Query: 416  GP------------QGLTGPPGKAGRRGRAGADGARGMPGDPGVK--GDRGFDGLPGLPG 461
            GP            +G  GPPG  G RG  G  G  G+PG PG    G RG  G PGL G
Sbjct: 342  GPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKG 401

Query: 462  EKGHRGD--------------TGAQGLPGPPGEDGERGD-------------DGEIGPRG 494
             KG RG                G+ GLPG PG  G  GD              G +G  G
Sbjct: 402  SKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPG 461

Query: 495  LPGESGPRGLLGP--------KGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT 546
            +PG  GP+G  G          GPPG+PG PG+ G+ G  G +G+ G +G PG PG  G 
Sbjct: 462  IPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGL 521

Query: 547  PGTQGLPGPQGAIGPHGEKG----PQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSG 602
            PG  G PG QG  G  GEKG    P+G+ G+PG PG  G PG  G +G PGT G +G  G
Sbjct: 522  PGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPG 581

Query: 603  PQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF--KGDIGVKGDRGEVGVPGSRGE 660
            P+G L   G +G +G  G  G  G  G  G  G PG+  +G+ G++G +G  G PG  GE
Sbjct: 582  PKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGE 641

Query: 661  DGPEG----------PKGRTGPTGDPGP---PGLMGEKGKLGVPGLPG-----------Y 696
             GP G          P G  GP G PGP   PG+ G  GK G PGLPG           +
Sbjct: 642  AGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF 701

Query: 697  PGRQGPKGSLGFPGFPGA---SGEKGARGLSGKSGPRGERG------PTGPR--GQRGPR 745
            PG  GPKG  GFPG  G+    G+ G  GL GK G  G +G      P GP   G  G R
Sbjct: 702  PGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGER 761

Query: 746  GATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK--------DGLPG 797
            G +G+ G  G  G  G  G PG  GL GP+G  G PGP G  GPPG+         GLPG
Sbjct: 762  GNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPG 821

Query: 798  HPGQRGEVGFQGKTGPPGPPGVVG--PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGK 855
              G +G+ G +GKTGP G PG+ G    G  GETG  G  GH G  GP G++G PG    
Sbjct: 822  LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPG---- 877

Query: 856  EGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGA 915
                 +PG  G PG+DG  G+ GFPG  G PG  G PG  G  G  G PG  G  G  GA
Sbjct: 878  -----NPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932

Query: 916  AGSGGPIGPPGRP------GPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP 969
             G  G  G PG        G +G PG  G  G PGEKG  G  G  G++G  GLPGPAGP
Sbjct: 933  KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992

Query: 970  PGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGH 1029
            PG  G+ G  G  G+PG +G  G+ G  G PG  G  G +G PG AG  G PG  G QG 
Sbjct: 993  PGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGD 1052

Query: 1030 FGAKG-DEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADG 1088
             G  G  EGTR   GPPGP G  GLPG  G+KGE      MG PGPPG  GPAGP GA G
Sbjct: 1053 KGEPGYSEGTRP--GPPGPTGDPGLPGDMGKKGE------MGQPGPPGHLGPAGPEGAPG 1104

Query: 1089 PQGPPGGVGNLGPPGEKG---------EPGESGSPGIQGEPGVKGPRGERGEKGESGQPG 1139
              G PG  G  GP G+ G          PG  G PG+ G PG  GP G RG++G  G PG
Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG 1164

Query: 1140 EPG----------PPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGED 1189
              G          PPGP+G  G  G KG+ G  GFPG PG  G  G  G  G  G  G  
Sbjct: 1165 PAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFP 1224

Query: 1190 GEPGQPGS--PGPTGENGPPGPLGKRG---PAGSPGSE--GRQGGKGAKGDPGAIGAPGK 1242
            G PG PG+  PG TG  GPPG  G  G   P G PGS   G +G KG+ G PG  G PG 
Sbjct: 1225 GPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGT 1284

Query: 1243 TGPVGPAGPAGKPGPDGL---------RGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGL 1293
             G +GP G  G PG  GL         +G PG  G++G PG  G  GPPGP+GP G PG+
Sbjct: 1285 AGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGV 1344

Query: 1294 RGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP 1353
            RGD G       PG  G  G PGE G +G+ G PGP G+ G  G  G PG        G 
Sbjct: 1345 RGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKD------GK 1398

Query: 1354 PGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1391
            PG PGPAG KG KG+ G  GP G  G+ G  G  G  G
Sbjct: 1399 PGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSG 1436



 Score =  831 bits (2147), Expect = 0.0
 Identities = 510/1154 (44%), Positives = 581/1154 (50%), Gaps = 97/1154 (8%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVE-----------GPPGPEG---PAGLIGPPGI 308
            P      G +G KG+ G P    P    +           GPPGP G   P G  GPPG+
Sbjct: 320  PGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGV 379

Query: 309  QGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLM-LPFRFGSGGGDKGPVVAAQEAQA 367
             G+PG    PG RG PG  GL GS G  G PG   M  P   G  G    P         
Sbjct: 380  PGSPGS-SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPP 438

Query: 368  QAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPR--GPQGLTGPPG 425
              I+ +     +GPPG  G  G  G  G PG  G KGE G L  Q P   GP GL G PG
Sbjct: 439  GDIVFR-----KGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493

Query: 426  KAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGE------KGHRGDT-GAQGLPGPP 478
              G +G  G  GA G+ G PG  G+ G  G PG PG       KG +G+T   +G  G P
Sbjct: 494  LHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVP 553

Query: 479  GEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEP 538
            G+ G RG  G  G  G+PG  G +GL GPKG   + G  G +G  G  G  GS GP G  
Sbjct: 554  GDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPA 613

Query: 539  GPPGQ--QGTPGTQGLPGPQGAIGPHGEKGPQGKPGL----PGMPGSDGPPGHPGKEGPP 592
            GPPG   QG PG QG  G  GA GP GE GP+G+  +    PG PG  GPPGHPG +GPP
Sbjct: 614  GPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPP 673

Query: 593  GTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEV 652
            G  G+ G  G  G    PGP G  G+ GI G  G  G KG+ GFPG KG +G  G  GE 
Sbjct: 674  GIPGSLGKCGDPG---LPGPDGEPGIPGI-GFPGPPGPKGDQGFPGTKGSLGCPGKMGEP 729

Query: 653  GVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFP 712
            G+PG  G  G +G      P G PG PG  GE+G  G  G  G PG  G       PG P
Sbjct: 730  GLPGKPGLPGAKGEPAVAMP-GGPGTPGFPGERGNSGEHGEIGLPGLPG------LPGTP 782

Query: 713  GASGEKGARGLSGKSGPRGERGPTGP--RGQRGPRGATGKSGAKGTSGGDGPHGPPGERG 770
            G  G  G RG  G+ GP GE+GP G    G RG +G  G +G KG  G  G  GP G+ G
Sbjct: 783  GNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPG 842

Query: 771  LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP---------PGVVG 821
            +PG    +GFPG  G PG PG  G  G  GQRG  G  G  GPPG          PG +G
Sbjct: 843  IPGLDR-SGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIG 901

Query: 822  PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP---GKDGPAGLRG 878
            P G  G  G  G+RG PG PG  G++G PG  G++G KG+PGP       G  G  GL+G
Sbjct: 902  PPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKG 961

Query: 879  FPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAG 938
            F G  G  G  G PG+ G +G  G PGPAG PG RG  GS    G PG PG +G PG+ G
Sbjct: 962  FAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS---TGNPGEPGLRGIPGSMG 1018

Query: 939  EKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE--------DGDKGEVGDPGQKGT 990
              G+PG KG  G  G  G  G  GLPG  G  G  GE         G  G  GDPG  G 
Sbjct: 1019 NMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGD 1078

Query: 991  KGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP---GP 1047
             G KGE G PGPPG +GP G  GA G+ G PG  G  G  G  G +G +G  GPP   GP
Sbjct: 1079 MGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGP 1138

Query: 1048 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1107
             GL G PG  G  G  GD G  G PGP G +G  G   A     PPG  GN G  G KG+
Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRA-----PPGPRGNPGAQGAKGD 1193

Query: 1108 PGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGP--KGPTGDDGPKGNPGPVGFP 1165
             G  G PG+ G  G  G  G RG  G  G PG PG PG    G TG+ GP G+ G  G P
Sbjct: 1194 RGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAP 1253

Query: 1166 GDPGPPGEG--GPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEG 1223
            G PGPPG    G +G  G+ G  G  G PG  G  GP G  G PG  G  GP G PG +G
Sbjct: 1254 GPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313

Query: 1224 RQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDG---LRGLPGSVGQQGRPGATGQAG 1280
              G KG KG+PG +G+ G  GP+GP GP G  G  G   +  LPGS G  G PG  G  G
Sbjct: 1314 FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373

Query: 1281 PPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMG 1340
             PGP GPPG  G  G  G  G+ G P   G  GP GE+G KG +G PGP GS       G
Sbjct: 1374 EPGPPGPPGNLGPCGPRGKPGKDGKP---GTPGPAGEKGNKGSKGEPGPAGSD------G 1424

Query: 1341 IPGASGPIGPGGPP 1354
            +PG  G  G  G P
Sbjct: 1425 LPGLKGKRGDSGSP 1438



 Score =  804 bits (2077), Expect = 0.0
 Identities = 516/1242 (41%), Positives = 594/1242 (47%), Gaps = 217/1242 (17%)

Query: 380  GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGAR 439
            G  G  G  G PGP G PG  G  G  G  GPQGP+G  GL G  G  G RG +G  G  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 440  GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 499
            G PG PG  G+ G  GL G+PG  G +G+ G  GLPG  G  G  G  G  G +G P + 
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 500  GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQG-- 557
                L   KG PG+PG PG +G+ GP G  G +GP   PGPPG  G PG  G  GP+G  
Sbjct: 163  EDIEL-DAKGDPGLPGAPGPQGLPGPPGFPGPVGP---PGPPGFFGFPGAMGPRGPKGHM 218

Query: 558  ---AIGPHGEKGPQGKPGLPGMPGS-----DGPPGHPGKEGPPGTKGNQGPSGPQGPLGY 609
                IG  GE+G +G  G PG PG+      GP      +G  G KG  G  GP GP G 
Sbjct: 219  GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGL 278

Query: 610  PGP--------------RGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVP 655
            PG               +G  G DG+ G  G +G KG  GFPG  G+ G+KG +G++G P
Sbjct: 279  PGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPP 338

Query: 656  GSRGED---------------GPEGPKGRTGPTGDPGPPGLMGEKG--KLGVPGLPGYPG 698
            G RG                 GP GP+G  GP G  GPPG+ G  G  + G+ G PG+PG
Sbjct: 339  GFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPG 398

Query: 699  RQGPKG--------SLGFPGFPGASGEKGARGLSGKSGPRGE----RGPTGPRGQRGPRG 746
             +G KG        ++G PG PG +G  G  G  G  GP G+    +GP G  G  G  G
Sbjct: 399  LKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLG 458

Query: 747  ATGKSGAKGTSGGDG------PH--GPPGERGLPGPQGPNGFPGP------KGPPGPPGK 792
            + G  G  G  G  G      P+  GPPG  GLPG  G  G PG       KG PG PG 
Sbjct: 459  SPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGN 518

Query: 793  DGLPGHPGQRGEVGFQGKTGPPG----PPGVVGPQGAAGETGPMGERGHPGPPGPPGEQG 848
             GLPG PG  G  G  G  G  G    P G VG  G  G  G  G +G  G PG PG +G
Sbjct: 519  TGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKG 578

Query: 849  LPGT------AGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSG 902
            LPG       +G++G +G PG PG+PG  GPAG  G PG     G  G PGL+G +G  G
Sbjct: 579  LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY----GPQGEPGLQGTQGVPG 634

Query: 903  PPGPAGSPGERG-------AAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD 955
             PGP G  G RG         G  GP GPPG PGPQGPPG  G  G  G+ G  GP G  
Sbjct: 635  APGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEP 694

Query: 956  GVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGT------------------------- 990
            G+ G +G PGP GP G  G  G KG +G PG+ G                          
Sbjct: 695  GIPG-IGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPG 753

Query: 991  -------KGNKGEHGP---------PGPPG------PIGPVGQPGAAGADGEPG------ 1022
                   +GN GEHG          PG PG      P G  GQPG  G  G PG      
Sbjct: 754  TPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGP 813

Query: 1023 --ARGPQGHFGAKGDEGTRGFNGPPGPIGLQGL-----------PGPSGEKGETGDVGPM 1069
              A+G  G  G KG +G RG  GP G  G+ GL           PG  G +GE G +G  
Sbjct: 814  RGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQR 873

Query: 1070 GPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGER 1129
            G PG PG  GP G +G  G  G PG +G  GPPG  G PG+ GSPGI   PGVKG RG  
Sbjct: 874  GYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGI---PGVKGQRGTP 930

Query: 1130 GEKGESGQPGEPGP------------PGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPR 1177
            G KGE G  G PGP            PG KG  G+ G KGN G  G PG  G  G  GP 
Sbjct: 931  GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPA 990

Query: 1178 GQDGAKGDRGEDGEPGQPGS---PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDP 1234
            G  G +GD G  G PG+PG    PG  G  G PG  GKRG  G PG  GR G  G  G  
Sbjct: 991  GPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQ 1050

Query: 1235 GAIGAPGKTGPV--GPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG 1292
            G  G PG +     GP GP G PG  G  G  G +GQ G PG  G AGP G  G PG PG
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 1293 LRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPG---PQGSPGQKGEMGIPGASGPIG 1349
            L G  G  G+ G  G+ GL+GPPG +G  G  G PG   P G  G +G  GIPG +G  G
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170

Query: 1350 -------PGGPPGLPGPAGPK------------GAKGATGPGGPKGEKGVQGPPGHPGPP 1390
                   P GP G PG  G K            G KGA G  GP+G  G++G PG PG P
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 1391 GEVIQPLPIQMPKKT-RRSVDGSRLMQEDEAIPTGGAPGSPG 1431
            G +I       P +T  R   GSR         + GAPG PG
Sbjct: 1231 GAII-------PGQTGNRGPPGSR--------GSPGAPGPPG 1257



 Score =  751 bits (1940), Expect = 0.0
 Identities = 466/1111 (41%), Positives = 548/1111 (49%), Gaps = 114/1111 (10%)

Query: 218  YESCEQKELECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGE 277
            Y++ ++K  E   G    P   +  R  + P   P     P +  P  + A G  GLKG 
Sbjct: 347  YDTYQEKGDEGTPG----PPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGS 402

Query: 278  KGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGD-------PGERGPPGRAGLP 330
            KGE     PG    G PG  G AG  G PG  G PGP GD       PG+ G PG  G P
Sbjct: 403  KGERG--RPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSP 460

Query: 331  GSDGAPGPPGTSLMLPFRFGSGGGDKG-PVVAAQEAQAQAILQQARLALRGPPGPMGYTG 389
            G  G  GP G   +L  +     G  G P +           +Q    L+G PG  G TG
Sbjct: 461  GIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTG 520

Query: 390  RPGPLGQPGS---PGLKGESGDL----GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMP 442
             PG  G PG+   PGLKGE G+     G  G  G  GL G PG+ G  G  G  G +G+P
Sbjct: 521  LPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLP 580

Query: 443  GDPG---VKGDRGFDGLPGLPGEKGHRGDTGAQGLPG--PPGEDGERGDDGEIGPRGLPG 497
            G  G   + G++G  G PG PG  G  G  G  G PG  P GE G +G  G  G  G PG
Sbjct: 581  GPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPG 640

Query: 498  ESGPRGLLGPK----GPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT---- 549
            E+GPRG L       GPPG PGPPG  G  GP G  GSLG  G+PG PG  G PG     
Sbjct: 641  EAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIG 700

Query: 550  ----------QGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPG--HPGKEGPPGTKGN 597
                      QG PG +G++G  G+ G  G PG PG+PG+ G P    PG  G PG  G 
Sbjct: 701  FPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGE 760

Query: 598  QGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIG--VKGDRGEVGVP 655
            +G SG  G +G PG  G+ G  G  GL G +G+ G+ G PG +G  G  ++G RG  G+P
Sbjct: 761  RGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLP 820

Query: 656  GSRGEDGPEGPKGRTGPTGDPGPPGL--MGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPG 713
            G  G  G +G +G+TGP GDPG PGL   G  G+ G PG+PG+ G  GP G  G+PG PG
Sbjct: 821  GLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPG 880

Query: 714  ASGEKGARGLSGKSGPRGERGPTGPRGQRGP---RGATGKSGAKGTSGGDGPHGPPGERG 770
              G  G  G+ G  G  G  GP GP G  G    RG+ G  G KG  G  G  G  G++G
Sbjct: 881  ILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKG 940

Query: 771  LPGPQ------GPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQG 824
             PGP       G  G PG KG  G PG+ G  G PG  G  G +G  GP GPPG   P+G
Sbjct: 941  NPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPG---PRG 997

Query: 825  AAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERG 884
              G TG  GE G  G PG  G  G+PG+ GK GT G PG  G PG  G  GL+G  GE G
Sbjct: 998  DLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPG 1057

Query: 885  L--------PGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGA 936
                     PG  G PGL G+ G  G  G  G PG  G AG  G  G PG PG  G PG 
Sbjct: 1058 YSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGP 1117

Query: 937  AGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE 996
             G+ G  G KG +GP G   ++GP GLPG  G PG  G  GD+G  G PG  G KG  G 
Sbjct: 1118 HGDLGFKGIKGLLGPPG---IRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGL 1174

Query: 997  -HGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQG--L 1053
               PPGP G  G  G  G  GA G PG  G +G  G  G  G  G  G PGP GL G  +
Sbjct: 1175 LRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAII 1234

Query: 1054 PGPSGEKGETGDVGPMGPPGPPGP--------RGPAGPNGADGPQGPPGGVGNLGPPGEK 1105
            PG +G +G  G  G  G PGPPGP        +G  G  G  GP+GPPG  G++GPPG  
Sbjct: 1235 PGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRL 1294

Query: 1106 GEPGESGSPGIQGEPGVKGPRGERGEKGESG----------------------------- 1136
            G PG  G PG +G+PG +G  G +GEKG  G                             
Sbjct: 1295 GAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKII 1354

Query: 1137 -QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQP 1195
              PG PGPPG  G  G  G  G PGP G  G  GP G+ G  G+ G  G  GE G  G  
Sbjct: 1355 SLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSK 1414

Query: 1196 GSPGPTGENGPPGPLGKRGPAGSPGSEGRQG 1226
            G PGP G +G PG  GKRG +GSP +   +G
Sbjct: 1415 GEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445



 Score =  617 bits (1592), Expect = e-176
 Identities = 390/938 (41%), Positives = 464/938 (49%), Gaps = 175/938 (18%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVLE--------PGMLVEGPPGPEGPAGLIGPPGIQGNPGP 314
            P    A G  GLKGEKGE    E        PG+   G PG +G  G+ G PG++G PGP
Sbjct: 525  PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGL--RGQPGRKGLDGIPGTPGVKGLPGP 582

Query: 315  VGD------PGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--------GDKGPVV 360
             G+       G++GPPG  G PGS G  GP G     P  +G  G        G  G   
Sbjct: 583  KGELALSGEKGDQGPPGDPGSPGSPGPAGPAG-----PPGYGPQGEPGLQGTQGVPGAPG 637

Query: 361  AAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLG---------- 410
               EA  +  L  +   + GPPGP G  G PGP G PG PG  G+ GD G          
Sbjct: 638  PPGEAGPRGELSVST-PVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGI 696

Query: 411  -------PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDR-----GFDGLPG 458
                   P GP+G QG  G  G  G  G+ G  G  G PG PG KG+      G  G PG
Sbjct: 697  PGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPG 756

Query: 459  LPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGP-----KGPPGI 513
             PGE+G+ G+ G  GLPG PG  G  G++G  GPRG PG+ GP G  GP     +GP G 
Sbjct: 757  FPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGA 816

Query: 514  PGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQ-----GTPGTQGLPGPQGAIGPHGEKGPQ 568
             G PG+ G+ G QG +G  GP+G+PG PG       G  G+ G+PG QG +GP G++G  
Sbjct: 817  QGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876

Query: 569  GKPGLPGMPGSDGP---PGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLK 625
            G PG+ G PG DG     G PG  GPPG  GN G  G +G  G PG +G +G  G +G +
Sbjct: 877  GNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQ 936

Query: 626  GHKG------------EKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPT 673
            G KG            +KGE G  GF G+ G KG+RG  G+PG +G  G  GP G  GP 
Sbjct: 937  GDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPR 996

Query: 674  GDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER 733
            GD G  G  GE G  G+PG  G  G  G KG  G  GFPG +G  G  G+ G  G +GE 
Sbjct: 997  GDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056

Query: 734  GPTGPRGQR-GPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK 792
            G +   G R GP G TG  G  G  G        GE G PGP G  G  GP+G PG PG 
Sbjct: 1057 GYS--EGTRPGPPGPTGDPGLPGDMG------KKGEMGQPGPPGHLGPAGPEGAPGSPGS 1108

Query: 793  DGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAG---ETGPMGERGH------PGPPG- 842
             GLPG PG  G++GF+G  G  GPPG+ GP G  G     GPMG RG       PGP G 
Sbjct: 1109 PGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE 1168

Query: 843  ---------PPGEQGLPGTAGKEGTKGDPGPPGAPGKDG---------PAGLRGFPGERG 884
                     PPG +G PG  G +G +G PG PG PG+ G         P G+ GFPG  G
Sbjct: 1169 KGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPG 1228

Query: 885  LPGTA--------GGPGLKGNEGPSGPPGPAGS--------------PGERGAAGSGGPI 922
            LPG          G PG +G+ G  GPPGP GS              PG +G  G+ G +
Sbjct: 1229 LPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDM 1288

Query: 923  GPPGR---------PGPQGPPGAAGEKGVPGEKG------------PIGPTGRDGVQGPV 961
            GPPGR         PGP+G PG  G  GV GEKG            PIGP G  GV+G  
Sbjct: 1289 GPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDP 1348

Query: 962  G------LPGPAGPPGVAGEDGDKGEVGDPGQKGT------KGNKGEHGPPGPPGPIGPV 1009
            G      LPG  GPPG  GE G +GE G PG  G       +G  G+ G PG PGP G  
Sbjct: 1349 GTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEK 1408

Query: 1010 G------QPGAAGADGEPGARGPQGHFGAKGDEGTRGF 1041
            G      +PG AG+DG PG +G +G  G+     TRGF
Sbjct: 1409 GNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGF 1446



 Score =  368 bits (945), Expect = e-101
 Identities = 255/627 (40%), Positives = 279/627 (44%), Gaps = 122/627 (19%)

Query: 915  AAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP---PG 971
            AA  G      G+    G  G  GEKG P   GP G  G+ G  GP GLPGP GP   PG
Sbjct: 26   AASKGCVCKDKGQCFCDGAKGEKGEKGFP---GPPGSPGQKGFTGPEGLPGPQGPKGFPG 82

Query: 972  VAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGE---PGARGPQG 1028
            + G  G KG  G  G  G  G+ G  G PG  GP G VG PG +G+ GE   PG  G  G
Sbjct: 83   LPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLG 142

Query: 1029 HFGAKGDEGTRGFNGPP-----------GPIGLQGLPGPSGEKGETGDVGPMGPPGPP-- 1075
            + G  G  G +G  G P           G  GL G PGP G  G  G  GP+GPPGPP  
Sbjct: 143  YPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGF 202

Query: 1076 -------GPRGP--------------AGPNGADGPQGPPGGV------------------ 1096
                   GPRGP               G  G  GP GPPG V                  
Sbjct: 203  FGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKG 262

Query: 1097 -----GNLGPPGEKGEPGES--------GSPGIQGEP---GVKGPRGERGEKGESGQPGE 1140
                 G  GPPG  G PGES        G PG+QG+P   GV G  G  G KG  G PG 
Sbjct: 263  DKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGL 322

Query: 1141 PGPPGPKGPTGDDGPKGNPGPVGF------PGDPGPPGEGGPRGQDGAKGDRGEDGEPGQ 1194
             G  G KG  GD GP G  GP  +       GD G PG  GPRG  G +G  G  G PG 
Sbjct: 323  MGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGS 382

Query: 1195 PGS--PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA 1252
            PGS  PG  G  G PG  G +G  G PG +      G  G PG  G+PG  G  GP GP 
Sbjct: 383  PGSSRPGLRGAPGWPGLKGSKGERGRPGKD----AMGTPGSPGCAGSPGLPGSPGPPGPP 438

Query: 1253 G----KPGPDGLRGLPGSVGQQGRPGATGQAGP-----------PGPVGPPGLPGLRGDA 1297
            G    + GP G  GLPG +G  G PG  G  G            PGP G PGLPGL G  
Sbjct: 439  GDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVK 498

Query: 1298 GAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGE----------MGIPGASGP 1347
            G  G +G  GL G  G PG  G  G  G PG QG PG KGE          +G+PG  G 
Sbjct: 499  GIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGL 558

Query: 1348 IGPGGPPGLPGPAGPKGAKGATGPGGP---KGEKGVQGPPGHPGPPGEVIQPLPIQMPKK 1404
             G  G  GL G  G  G KG  GP G     GEKG QGPPG PG PG    P P      
Sbjct: 559  RGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPG---SPGPAGPAGP 615

Query: 1405 TRRSVDGSRLMQEDEAIPTGGAPGSPG 1431
                  G   +Q  + +P  GAPG PG
Sbjct: 616  PGYGPQGEPGLQGTQGVP--GAPGPPG 640



 Score =  149 bits (377), Expect = 2e-35
 Identities = 96/253 (37%), Positives = 121/253 (47%), Gaps = 38/253 (15%)

Query: 270  GPRGLKGEKGEPAVLEPGMLV------EGPPGPEGPAGLIGPPG--------IQGNPGPV 315
            GP G++G  G P +  PG ++       GPPG  G  G  GPPG        I+G+ G +
Sbjct: 1216 GPTGIEGFPGPPGL--PGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSM 1273

Query: 316  GDPGERGPPGRAG---LPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQ 372
            G PG +GPPG AG    PG  GAPG PG    LP   G  G    P V  +         
Sbjct: 1274 GHPGPKGPPGTAGDMGPPGRLGAPGTPG----LPGPRGDPGFQGFPGVKGE--------- 1320

Query: 373  QARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGR 432
                  +G PG +G  G PGP+G  G PG++G+ G L      G  G  G PG+ G +G 
Sbjct: 1321 ------KGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGE 1374

Query: 433  AGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGP 492
             G  G  G  G  G +G  G DG PG PG  G +G+ G++G PGP G DG  G  G+ G 
Sbjct: 1375 PGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGD 1434

Query: 493  RGLPGESGPRGLL 505
             G P     RG +
Sbjct: 1435 SGSPATWTTRGFV 1447


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
            sapiens]
          Length = 1670

 Score =  894 bits (2311), Expect = 0.0
 Identities = 580/1363 (42%), Positives = 670/1363 (49%), Gaps = 260/1363 (19%)

Query: 270  GPRGLKGEKGEPAVL-EPGML----VEGPPGPEGPAG---------------LIGPPGIQ 309
            G +G KGEKG P     PG       EG PGP+GP G               + G PG  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 310  GNPGPVGDPGERGPPGRAGLPGSDGA------PGPPGTSLMLPFRFGSGG--GDKGPVVA 361
            G+PG  G PG  GP G  G+PG  G+      PG PGT L  P   G+ G  G KG    
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGT-LGYPGIPGAAGLKGQKGAPAK 161

Query: 362  AQEAQAQAILQQARLALRGPPGPMGYTGRPG---PLGQPGSPGLKGESGDLGPQGP---- 414
             ++ +  A   +    L G PGP G  G PG   P+G PG PG  G  G +GP+GP    
Sbjct: 162  EEDIELDA---KGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHM 218

Query: 415  ----------RGPQGLTGPPGKAGR--------------RGRAGADGA------------ 438
                      RG +GLTGPPG  G               +G  G  GA            
Sbjct: 219  GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGL 278

Query: 439  --------RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI 490
                    +G PGDPG++G  G DG+PG PG +G +G+   +G PG  GEDG +G  G+I
Sbjct: 279  PGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN---RGFPGLMGEDGIKGQKGDI 335

Query: 491  GP------------------RGLPGESGPRGLLGPKGP---PGIPGPPG-----VRGMDG 524
            GP                   G PG  GPRG  GP+GP   PG+PG PG     +RG  G
Sbjct: 336  GPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPG 395

Query: 525  PQGPKGSLGPQGEPGP-----PGQQGTPGTQGLPGPQGAIGPHGE----KGPQGKPGLPG 575
              G KGS G +G PG      PG  G  G+ GLPG  G  GP G+    KGP G  GLPG
Sbjct: 396  WPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPG 455

Query: 576  MPGSDGPPGHPGKEGPPGTKGNQGP--SGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGE 633
              GS G PG  G +G PG    Q P   GP G  G PG  GVKG+ G +G  G KG  G 
Sbjct: 456  YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515

Query: 634  DG---------FPGFKGDIGVKGDRGE-------VGVPGSRGEDGPEGPKGRTGPTGDPG 677
             G         FPG +GD G+KG++GE       VGVPG  G  G  G KG  G  G PG
Sbjct: 516  PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575

Query: 678  PPGLMGEKGKL------------GVPGLPGYPGRQGPKGSLGF-----PGFPGASGEKGA 720
              GL G KG+L            G PG PG PG  GP G  G+     PG  G  G  GA
Sbjct: 576  VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635

Query: 721  RGLSGKSGPRGER----------GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG 770
             G  G++GPRGE           GP GP G  GP+G  G  G+ G  G  G  GP GE G
Sbjct: 636  PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPG 695

Query: 771  LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP--------PGVVGP 822
            +PG   P G PGPKG  G PG  G  G PG+ GE G  GK G PG         PG  G 
Sbjct: 696  IPGIGFP-GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGT 754

Query: 823  QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE 882
             G  GE G  GE G  G PG PG  G PG  G +G +GDPG PG PG+ GP G R   G 
Sbjct: 755  PGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPG-RCIEGP 813

Query: 883  RGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSG--GPIGPPGRPGPQGPPGAAGEK 940
            RG  G  G  GLKG +G  G  GP G PG  G   SG  G  G PG PG QG  G  G++
Sbjct: 814  RGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQR 873

Query: 941  GVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPG------QKGTKGNK 994
            G PG  G +GP G DGV G +G PG  GPPG  G  G  G+ G PG      Q+GT G K
Sbjct: 874  GYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAK 933

Query: 995  GEHGPPGPPGP------IGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPI 1048
            GE G  G PGP      IG  G+PG  G  G PG            ++G RG  G PG  
Sbjct: 934  GEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPG------------EKGNRGVPGMPGLK 981

Query: 1049 GLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP 1108
            GL+GLPGP+G  G  GD+G  G PG PG RG  G  G  G  G  G  G LG PG  G P
Sbjct: 982  GLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRP 1041

Query: 1109 GESGSPGIQGE-----------PGVKGPRGERG---EKGESGQPGEPGPPGPKGPTGDDG 1154
            G  G  G+QG+           PG  GP G+ G   + G+ G+ G+PGPPG  GP G +G
Sbjct: 1042 GLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101

Query: 1155 PKGNPGPVGFPGDPGPPGEGGPRGQDGAKGD---RGEDGEPGQPGSPGPTG------ENG 1205
              G+PG  G PG PGP G+ G +G  G  G    RG  G PG PGSPGP G       +G
Sbjct: 1102 APGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDG 1161

Query: 1206 PPGPLGKRGPAG----SPGSEGRQGGKGAKGD---------PGAIGAPGKTGPVGPAGPA 1252
             PGP G++G  G     PG  G  G +GAKGD         PG  GA G  GP GP G  
Sbjct: 1162 IPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIE 1221

Query: 1253 GKPGPDGLRG--LPGSVGQQGRPGATGQAGPPGPVGPPG--LPGLRGDAGAKGE---KGH 1305
            G PGP GL G  +PG  G +G PG+ G  G PGP GPPG  + G++GD G+ G    KG 
Sbjct: 1222 GFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP 1281

Query: 1306 PGLIGLIGPPGEQGEKGDRGLPGP------QGSPGQKGEMGIPGASGPIGPGGPPGLPGP 1359
            PG  G +GPPG  G  G  GLPGP      QG PG KGE G PG  G IGP GP G  GP
Sbjct: 1282 PGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGP 1341

Query: 1360 AGPKG---------AKGATGPGGPKGEKGVQGPPGHPGPPGEV 1393
             G +G           G+ GP G  GE G+QG PG PGPPG +
Sbjct: 1342 PGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNL 1384



 Score =  874 bits (2257), Expect = 0.0
 Identities = 551/1298 (42%), Positives = 639/1298 (49%), Gaps = 201/1298 (15%)

Query: 262  EPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGER 321
            +P    A GP+GL G  G P          GP GP GP G  G PG  G  GP G  GER
Sbjct: 172  DPGLPGAPGPQGLPGPPGFP----------GPVGPPGPPGFFGFPGAMGPRGPKGHMGER 221

Query: 322  --GPPGRAGLPGSDGAPGPPGTSLML----PFRFGSGG--GDKGPVVAAQEAQAQAILQQ 373
              G  G  G+ G  G PGPPGT ++       R    G  GDKG +          +  +
Sbjct: 222  VIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGE 281

Query: 374  ARLALRGPPGPMGYTGRPGPLGQPGSPG------------------LKGESGDLGPQGPR 415
            +  + +G PG  G  G+PG  G PG PG                  +KG+ GD+GP G R
Sbjct: 282  SYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFR 341

Query: 416  GP------------QGLTGPPGKAGRRGRAGADGARGMPGDPGVK--GDRGFDGLPGLPG 461
            GP            +G  GPPG  G RG  G  G  G+PG PG    G RG  G PGL G
Sbjct: 342  GPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKG 401

Query: 462  EKGHRGD--------------TGAQGLPGPPGEDGERGD-------------DGEIGPRG 494
             KG RG                G+ GLPG PG  G  GD              G +G  G
Sbjct: 402  SKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPG 461

Query: 495  LPGESGPRGLLGP--------KGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT 546
            +PG  GP+G  G          GPPG+PG PG+ G+ G  G +G+ G +G PG PG  G 
Sbjct: 462  IPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGL 521

Query: 547  PGTQGLPGPQGAIGPHGEKG----PQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSG 602
            PG  G PG QG  G  GEKG    P+G+ G+PG PG  G PG  G +G PGT G +G  G
Sbjct: 522  PGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPG 581

Query: 603  PQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF--KGDIGVKGDRGEVGVPGSRGE 660
            P+G L   G +G +G  G  G  G  G  G  G PG+  +G+ G++G +G  G PG  GE
Sbjct: 582  PKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGE 641

Query: 661  DGPEG----------PKGRTGPTGDPGP---PGLMGEKGKLGVPGLPG-----------Y 696
             GP G          P G  GP G PGP   PG+ G  GK G PGLPG           +
Sbjct: 642  AGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF 701

Query: 697  PGRQGPKGSLGFPGFPGA---SGEKGARGLSGKSGPRGERG------PTGPR--GQRGPR 745
            PG  GPKG  GFPG  G+    G+ G  GL GK G  G +G      P GP   G  G R
Sbjct: 702  PGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGER 761

Query: 746  GATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK--------DGLPG 797
            G +G+ G  G  G  G  G PG  GL GP+G  G PGP G  GPPG+         GLPG
Sbjct: 762  GNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPG 821

Query: 798  HPGQRGEVGFQGKTGPPGPPGVVG--PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGK 855
              G +G+ G +GKTGP G PG+ G    G  GETG  G  GH G  GP G++G PG    
Sbjct: 822  LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPG---- 877

Query: 856  EGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGA 915
                 +PG  G PG+DG  G+ GFPG  G PG  G PG  G  G  G PG  G  G  GA
Sbjct: 878  -----NPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932

Query: 916  AGSGGPIGPPGRP------GPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP 969
             G  G  G PG        G +G PG  G  G PGEKG  G  G  G++G  GLPGPAGP
Sbjct: 933  KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992

Query: 970  PGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGH 1029
            PG  G+ G  G  G+PG +G  G+ G  G PG  G  G +G PG AG  G PG  G QG 
Sbjct: 993  PGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGD 1052

Query: 1030 FGAKG-DEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADG 1088
             G  G  EGTR   GPPGP G  GLPG  G+KGE      MG PGPPG  GPAGP GA G
Sbjct: 1053 KGEPGYSEGTRP--GPPGPTGDPGLPGDMGKKGE------MGQPGPPGHLGPAGPEGAPG 1104

Query: 1089 PQGPPGGVGNLGPPGEKG---------EPGESGSPGIQGEPGVKGPRGERGEKGESGQPG 1139
              G PG  G  GP G+ G          PG  G PG+ G PG  GP G RG++G  G PG
Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG 1164

Query: 1140 EPG----------PPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGED 1189
              G          PPGP+G  G  G KG+ G  GFPG PG  G  G  G  G  G  G  
Sbjct: 1165 PAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFP 1224

Query: 1190 GEPGQPGS--PGPTGENGPPGPLGKRG---PAGSPGSE--GRQGGKGAKGDPGAIGAPGK 1242
            G PG PG+  PG TG  GPPG  G  G   P G PGS   G +G KG+ G PG  G PG 
Sbjct: 1225 GPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGT 1284

Query: 1243 TGPVGPAGPAGKPGPDGL---------RGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGL 1293
             G +GP G  G PG  GL         +G PG  G++G PG  G  GPPGP+GP G PG+
Sbjct: 1285 AGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGV 1344

Query: 1294 RGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP 1353
            RGD G       PG  G  G PGE G +G+ G PGP G+ G  G  G PG        G 
Sbjct: 1345 RGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKD------GK 1398

Query: 1354 PGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1391
            PG PGPAG KG KG+ G  GP G  G+ G  G  G  G
Sbjct: 1399 PGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSG 1436



 Score =  831 bits (2147), Expect = 0.0
 Identities = 510/1154 (44%), Positives = 581/1154 (50%), Gaps = 97/1154 (8%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVE-----------GPPGPEG---PAGLIGPPGI 308
            P      G +G KG+ G P    P    +           GPPGP G   P G  GPPG+
Sbjct: 320  PGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGV 379

Query: 309  QGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLM-LPFRFGSGGGDKGPVVAAQEAQA 367
             G+PG    PG RG PG  GL GS G  G PG   M  P   G  G    P         
Sbjct: 380  PGSPGS-SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPP 438

Query: 368  QAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPR--GPQGLTGPPG 425
              I+ +     +GPPG  G  G  G  G PG  G KGE G L  Q P   GP GL G PG
Sbjct: 439  GDIVFR-----KGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493

Query: 426  KAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGE------KGHRGDT-GAQGLPGPP 478
              G +G  G  GA G+ G PG  G+ G  G PG PG       KG +G+T   +G  G P
Sbjct: 494  LHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVP 553

Query: 479  GEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEP 538
            G+ G RG  G  G  G+PG  G +GL GPKG   + G  G +G  G  G  GS GP G  
Sbjct: 554  GDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPA 613

Query: 539  GPPGQ--QGTPGTQGLPGPQGAIGPHGEKGPQGKPGL----PGMPGSDGPPGHPGKEGPP 592
            GPPG   QG PG QG  G  GA GP GE GP+G+  +    PG PG  GPPGHPG +GPP
Sbjct: 614  GPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPP 673

Query: 593  GTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEV 652
            G  G+ G  G  G    PGP G  G+ GI G  G  G KG+ GFPG KG +G  G  GE 
Sbjct: 674  GIPGSLGKCGDPG---LPGPDGEPGIPGI-GFPGPPGPKGDQGFPGTKGSLGCPGKMGEP 729

Query: 653  GVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFP 712
            G+PG  G  G +G      P G PG PG  GE+G  G  G  G PG  G       PG P
Sbjct: 730  GLPGKPGLPGAKGEPAVAMP-GGPGTPGFPGERGNSGEHGEIGLPGLPG------LPGTP 782

Query: 713  GASGEKGARGLSGKSGPRGERGPTGP--RGQRGPRGATGKSGAKGTSGGDGPHGPPGERG 770
            G  G  G RG  G+ GP GE+GP G    G RG +G  G +G KG  G  G  GP G+ G
Sbjct: 783  GNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPG 842

Query: 771  LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP---------PGVVG 821
            +PG    +GFPG  G PG PG  G  G  GQRG  G  G  GPPG          PG +G
Sbjct: 843  IPGLDR-SGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIG 901

Query: 822  PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP---GKDGPAGLRG 878
            P G  G  G  G+RG PG PG  G++G PG  G++G KG+PGP       G  G  GL+G
Sbjct: 902  PPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKG 961

Query: 879  FPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAG 938
            F G  G  G  G PG+ G +G  G PGPAG PG RG  GS    G PG PG +G PG+ G
Sbjct: 962  FAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS---TGNPGEPGLRGIPGSMG 1018

Query: 939  EKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE--------DGDKGEVGDPGQKGT 990
              G+PG KG  G  G  G  G  GLPG  G  G  GE         G  G  GDPG  G 
Sbjct: 1019 NMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGD 1078

Query: 991  KGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP---GP 1047
             G KGE G PGPPG +GP G  GA G+ G PG  G  G  G  G +G +G  GPP   GP
Sbjct: 1079 MGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGP 1138

Query: 1048 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1107
             GL G PG  G  G  GD G  G PGP G +G  G   A     PPG  GN G  G KG+
Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRA-----PPGPRGNPGAQGAKGD 1193

Query: 1108 PGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGP--KGPTGDDGPKGNPGPVGFP 1165
             G  G PG+ G  G  G  G RG  G  G PG PG PG    G TG+ GP G+ G  G P
Sbjct: 1194 RGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAP 1253

Query: 1166 GDPGPPGEG--GPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEG 1223
            G PGPPG    G +G  G+ G  G  G PG  G  GP G  G PG  G  GP G PG +G
Sbjct: 1254 GPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313

Query: 1224 RQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDG---LRGLPGSVGQQGRPGATGQAG 1280
              G KG KG+PG +G+ G  GP+GP GP G  G  G   +  LPGS G  G PG  G  G
Sbjct: 1314 FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373

Query: 1281 PPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMG 1340
             PGP GPPG  G  G  G  G+ G P   G  GP GE+G KG +G PGP GS       G
Sbjct: 1374 EPGPPGPPGNLGPCGPRGKPGKDGKP---GTPGPAGEKGNKGSKGEPGPAGSD------G 1424

Query: 1341 IPGASGPIGPGGPP 1354
            +PG  G  G  G P
Sbjct: 1425 LPGLKGKRGDSGSP 1438



 Score =  804 bits (2077), Expect = 0.0
 Identities = 516/1242 (41%), Positives = 594/1242 (47%), Gaps = 217/1242 (17%)

Query: 380  GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGAR 439
            G  G  G  G PGP G PG  G  G  G  GPQGP+G  GL G  G  G RG +G  G  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 440  GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 499
            G PG PG  G+ G  GL G+PG  G +G+ G  GLPG  G  G  G  G  G +G P + 
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 500  GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQG-- 557
                L   KG PG+PG PG +G+ GP G  G +GP   PGPPG  G PG  G  GP+G  
Sbjct: 163  EDIEL-DAKGDPGLPGAPGPQGLPGPPGFPGPVGP---PGPPGFFGFPGAMGPRGPKGHM 218

Query: 558  ---AIGPHGEKGPQGKPGLPGMPGS-----DGPPGHPGKEGPPGTKGNQGPSGPQGPLGY 609
                IG  GE+G +G  G PG PG+      GP      +G  G KG  G  GP GP G 
Sbjct: 219  GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGL 278

Query: 610  PGP--------------RGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVP 655
            PG               +G  G DG+ G  G +G KG  GFPG  G+ G+KG +G++G P
Sbjct: 279  PGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPP 338

Query: 656  GSRGED---------------GPEGPKGRTGPTGDPGPPGLMGEKG--KLGVPGLPGYPG 698
            G RG                 GP GP+G  GP G  GPPG+ G  G  + G+ G PG+PG
Sbjct: 339  GFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPG 398

Query: 699  RQGPKG--------SLGFPGFPGASGEKGARGLSGKSGPRGE----RGPTGPRGQRGPRG 746
             +G KG        ++G PG PG +G  G  G  G  GP G+    +GP G  G  G  G
Sbjct: 399  LKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLG 458

Query: 747  ATGKSGAKGTSGGDG------PH--GPPGERGLPGPQGPNGFPGP------KGPPGPPGK 792
            + G  G  G  G  G      P+  GPPG  GLPG  G  G PG       KG PG PG 
Sbjct: 459  SPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGN 518

Query: 793  DGLPGHPGQRGEVGFQGKTGPPG----PPGVVGPQGAAGETGPMGERGHPGPPGPPGEQG 848
             GLPG PG  G  G  G  G  G    P G VG  G  G  G  G +G  G PG PG +G
Sbjct: 519  TGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKG 578

Query: 849  LPGT------AGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSG 902
            LPG       +G++G +G PG PG+PG  GPAG  G PG     G  G PGL+G +G  G
Sbjct: 579  LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY----GPQGEPGLQGTQGVPG 634

Query: 903  PPGPAGSPGERG-------AAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD 955
             PGP G  G RG         G  GP GPPG PGPQGPPG  G  G  G+ G  GP G  
Sbjct: 635  APGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEP 694

Query: 956  GVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGT------------------------- 990
            G+ G +G PGP GP G  G  G KG +G PG+ G                          
Sbjct: 695  GIPG-IGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPG 753

Query: 991  -------KGNKGEHGP---------PGPPG------PIGPVGQPGAAGADGEPG------ 1022
                   +GN GEHG          PG PG      P G  GQPG  G  G PG      
Sbjct: 754  TPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGP 813

Query: 1023 --ARGPQGHFGAKGDEGTRGFNGPPGPIGLQGL-----------PGPSGEKGETGDVGPM 1069
              A+G  G  G KG +G RG  GP G  G+ GL           PG  G +GE G +G  
Sbjct: 814  RGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQR 873

Query: 1070 GPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGER 1129
            G PG PG  GP G +G  G  G PG +G  GPPG  G PG+ GSPGI   PGVKG RG  
Sbjct: 874  GYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGI---PGVKGQRGTP 930

Query: 1130 GEKGESGQPGEPGP------------PGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPR 1177
            G KGE G  G PGP            PG KG  G+ G KGN G  G PG  G  G  GP 
Sbjct: 931  GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPA 990

Query: 1178 GQDGAKGDRGEDGEPGQPGS---PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDP 1234
            G  G +GD G  G PG+PG    PG  G  G PG  GKRG  G PG  GR G  G  G  
Sbjct: 991  GPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQ 1050

Query: 1235 GAIGAPGKTGPV--GPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG 1292
            G  G PG +     GP GP G PG  G  G  G +GQ G PG  G AGP G  G PG PG
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 1293 LRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPG---PQGSPGQKGEMGIPGASGPIG 1349
            L G  G  G+ G  G+ GL+GPPG +G  G  G PG   P G  G +G  GIPG +G  G
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170

Query: 1350 -------PGGPPGLPGPAGPK------------GAKGATGPGGPKGEKGVQGPPGHPGPP 1390
                   P GP G PG  G K            G KGA G  GP+G  G++G PG PG P
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 1391 GEVIQPLPIQMPKKT-RRSVDGSRLMQEDEAIPTGGAPGSPG 1431
            G +I       P +T  R   GSR         + GAPG PG
Sbjct: 1231 GAII-------PGQTGNRGPPGSR--------GSPGAPGPPG 1257



 Score =  751 bits (1940), Expect = 0.0
 Identities = 466/1111 (41%), Positives = 548/1111 (49%), Gaps = 114/1111 (10%)

Query: 218  YESCEQKELECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGE 277
            Y++ ++K  E   G    P   +  R  + P   P     P +  P  + A G  GLKG 
Sbjct: 347  YDTYQEKGDEGTPG----PPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGS 402

Query: 278  KGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGD-------PGERGPPGRAGLP 330
            KGE     PG    G PG  G AG  G PG  G PGP GD       PG+ G PG  G P
Sbjct: 403  KGERG--RPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSP 460

Query: 331  GSDGAPGPPGTSLMLPFRFGSGGGDKG-PVVAAQEAQAQAILQQARLALRGPPGPMGYTG 389
            G  G  GP G   +L  +     G  G P +           +Q    L+G PG  G TG
Sbjct: 461  GIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTG 520

Query: 390  RPGPLGQPGS---PGLKGESGDL----GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMP 442
             PG  G PG+   PGLKGE G+     G  G  G  GL G PG+ G  G  G  G +G+P
Sbjct: 521  LPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLP 580

Query: 443  GDPG---VKGDRGFDGLPGLPGEKGHRGDTGAQGLPG--PPGEDGERGDDGEIGPRGLPG 497
            G  G   + G++G  G PG PG  G  G  G  G PG  P GE G +G  G  G  G PG
Sbjct: 581  GPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPG 640

Query: 498  ESGPRGLLGPK----GPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT---- 549
            E+GPRG L       GPPG PGPPG  G  GP G  GSLG  G+PG PG  G PG     
Sbjct: 641  EAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIG 700

Query: 550  ----------QGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPG--HPGKEGPPGTKGN 597
                      QG PG +G++G  G+ G  G PG PG+PG+ G P    PG  G PG  G 
Sbjct: 701  FPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGE 760

Query: 598  QGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIG--VKGDRGEVGVP 655
            +G SG  G +G PG  G+ G  G  GL G +G+ G+ G PG +G  G  ++G RG  G+P
Sbjct: 761  RGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLP 820

Query: 656  GSRGEDGPEGPKGRTGPTGDPGPPGL--MGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPG 713
            G  G  G +G +G+TGP GDPG PGL   G  G+ G PG+PG+ G  GP G  G+PG PG
Sbjct: 821  GLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPG 880

Query: 714  ASGEKGARGLSGKSGPRGERGPTGPRGQRGP---RGATGKSGAKGTSGGDGPHGPPGERG 770
              G  G  G+ G  G  G  GP GP G  G    RG+ G  G KG  G  G  G  G++G
Sbjct: 881  ILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKG 940

Query: 771  LPGPQ------GPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQG 824
             PGP       G  G PG KG  G PG+ G  G PG  G  G +G  GP GPPG   P+G
Sbjct: 941  NPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPG---PRG 997

Query: 825  AAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERG 884
              G TG  GE G  G PG  G  G+PG+ GK GT G PG  G PG  G  GL+G  GE G
Sbjct: 998  DLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPG 1057

Query: 885  L--------PGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGA 936
                     PG  G PGL G+ G  G  G  G PG  G AG  G  G PG PG  G PG 
Sbjct: 1058 YSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGP 1117

Query: 937  AGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE 996
             G+ G  G KG +GP G   ++GP GLPG  G PG  G  GD+G  G PG  G KG  G 
Sbjct: 1118 HGDLGFKGIKGLLGPPG---IRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGL 1174

Query: 997  -HGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQG--L 1053
               PPGP G  G  G  G  GA G PG  G +G  G  G  G  G  G PGP GL G  +
Sbjct: 1175 LRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAII 1234

Query: 1054 PGPSGEKGETGDVGPMGPPGPPGP--------RGPAGPNGADGPQGPPGGVGNLGPPGEK 1105
            PG +G +G  G  G  G PGPPGP        +G  G  G  GP+GPPG  G++GPPG  
Sbjct: 1235 PGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRL 1294

Query: 1106 GEPGESGSPGIQGEPGVKGPRGERGEKGESG----------------------------- 1136
            G PG  G PG +G+PG +G  G +GEKG  G                             
Sbjct: 1295 GAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKII 1354

Query: 1137 -QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQP 1195
              PG PGPPG  G  G  G  G PGP G  G  GP G+ G  G+ G  G  GE G  G  
Sbjct: 1355 SLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSK 1414

Query: 1196 GSPGPTGENGPPGPLGKRGPAGSPGSEGRQG 1226
            G PGP G +G PG  GKRG +GSP +   +G
Sbjct: 1415 GEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445



 Score =  617 bits (1592), Expect = e-176
 Identities = 390/938 (41%), Positives = 464/938 (49%), Gaps = 175/938 (18%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVLE--------PGMLVEGPPGPEGPAGLIGPPGIQGNPGP 314
            P    A G  GLKGEKGE    E        PG+   G PG +G  G+ G PG++G PGP
Sbjct: 525  PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGL--RGQPGRKGLDGIPGTPGVKGLPGP 582

Query: 315  VGD------PGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--------GDKGPVV 360
             G+       G++GPPG  G PGS G  GP G     P  +G  G        G  G   
Sbjct: 583  KGELALSGEKGDQGPPGDPGSPGSPGPAGPAG-----PPGYGPQGEPGLQGTQGVPGAPG 637

Query: 361  AAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLG---------- 410
               EA  +  L  +   + GPPGP G  G PGP G PG PG  G+ GD G          
Sbjct: 638  PPGEAGPRGELSVST-PVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGI 696

Query: 411  -------PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDR-----GFDGLPG 458
                   P GP+G QG  G  G  G  G+ G  G  G PG PG KG+      G  G PG
Sbjct: 697  PGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPG 756

Query: 459  LPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGP-----KGPPGI 513
             PGE+G+ G+ G  GLPG PG  G  G++G  GPRG PG+ GP G  GP     +GP G 
Sbjct: 757  FPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGA 816

Query: 514  PGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQ-----GTPGTQGLPGPQGAIGPHGEKGPQ 568
             G PG+ G+ G QG +G  GP+G+PG PG       G  G+ G+PG QG +GP G++G  
Sbjct: 817  QGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876

Query: 569  GKPGLPGMPGSDGP---PGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLK 625
            G PG+ G PG DG     G PG  GPPG  GN G  G +G  G PG +G +G  G +G +
Sbjct: 877  GNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQ 936

Query: 626  GHKG------------EKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPT 673
            G KG            +KGE G  GF G+ G KG+RG  G+PG +G  G  GP G  GP 
Sbjct: 937  GDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPR 996

Query: 674  GDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER 733
            GD G  G  GE G  G+PG  G  G  G KG  G  GFPG +G  G  G+ G  G +GE 
Sbjct: 997  GDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056

Query: 734  GPTGPRGQR-GPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK 792
            G +   G R GP G TG  G  G  G        GE G PGP G  G  GP+G PG PG 
Sbjct: 1057 GYS--EGTRPGPPGPTGDPGLPGDMG------KKGEMGQPGPPGHLGPAGPEGAPGSPGS 1108

Query: 793  DGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAG---ETGPMGERGH------PGPPG- 842
             GLPG PG  G++GF+G  G  GPPG+ GP G  G     GPMG RG       PGP G 
Sbjct: 1109 PGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE 1168

Query: 843  ---------PPGEQGLPGTAGKEGTKGDPGPPGAPGKDG---------PAGLRGFPGERG 884
                     PPG +G PG  G +G +G PG PG PG+ G         P G+ GFPG  G
Sbjct: 1169 KGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPG 1228

Query: 885  LPGTA--------GGPGLKGNEGPSGPPGPAGS--------------PGERGAAGSGGPI 922
            LPG          G PG +G+ G  GPPGP GS              PG +G  G+ G +
Sbjct: 1229 LPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDM 1288

Query: 923  GPPGR---------PGPQGPPGAAGEKGVPGEKG------------PIGPTGRDGVQGPV 961
            GPPGR         PGP+G PG  G  GV GEKG            PIGP G  GV+G  
Sbjct: 1289 GPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDP 1348

Query: 962  G------LPGPAGPPGVAGEDGDKGEVGDPGQKGT------KGNKGEHGPPGPPGPIGPV 1009
            G      LPG  GPPG  GE G +GE G PG  G       +G  G+ G PG PGP G  
Sbjct: 1349 GTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEK 1408

Query: 1010 G------QPGAAGADGEPGARGPQGHFGAKGDEGTRGF 1041
            G      +PG AG+DG PG +G +G  G+     TRGF
Sbjct: 1409 GNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGF 1446



 Score =  368 bits (945), Expect = e-101
 Identities = 255/627 (40%), Positives = 279/627 (44%), Gaps = 122/627 (19%)

Query: 915  AAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP---PG 971
            AA  G      G+    G  G  GEKG P   GP G  G+ G  GP GLPGP GP   PG
Sbjct: 26   AASKGCVCKDKGQCFCDGAKGEKGEKGFP---GPPGSPGQKGFTGPEGLPGPQGPKGFPG 82

Query: 972  VAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGE---PGARGPQG 1028
            + G  G KG  G  G  G  G+ G  G PG  GP G VG PG +G+ GE   PG  G  G
Sbjct: 83   LPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLG 142

Query: 1029 HFGAKGDEGTRGFNGPP-----------GPIGLQGLPGPSGEKGETGDVGPMGPPGPP-- 1075
            + G  G  G +G  G P           G  GL G PGP G  G  G  GP+GPPGPP  
Sbjct: 143  YPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGF 202

Query: 1076 -------GPRGP--------------AGPNGADGPQGPPGGV------------------ 1096
                   GPRGP               G  G  GP GPPG V                  
Sbjct: 203  FGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKG 262

Query: 1097 -----GNLGPPGEKGEPGES--------GSPGIQGEP---GVKGPRGERGEKGESGQPGE 1140
                 G  GPPG  G PGES        G PG+QG+P   GV G  G  G KG  G PG 
Sbjct: 263  DKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGL 322

Query: 1141 PGPPGPKGPTGDDGPKGNPGPVGF------PGDPGPPGEGGPRGQDGAKGDRGEDGEPGQ 1194
             G  G KG  GD GP G  GP  +       GD G PG  GPRG  G +G  G  G PG 
Sbjct: 323  MGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGS 382

Query: 1195 PGS--PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA 1252
            PGS  PG  G  G PG  G +G  G PG +      G  G PG  G+PG  G  GP GP 
Sbjct: 383  PGSSRPGLRGAPGWPGLKGSKGERGRPGKD----AMGTPGSPGCAGSPGLPGSPGPPGPP 438

Query: 1253 G----KPGPDGLRGLPGSVGQQGRPGATGQAGP-----------PGPVGPPGLPGLRGDA 1297
            G    + GP G  GLPG +G  G PG  G  G            PGP G PGLPGL G  
Sbjct: 439  GDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVK 498

Query: 1298 GAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGE----------MGIPGASGP 1347
            G  G +G  GL G  G PG  G  G  G PG QG PG KGE          +G+PG  G 
Sbjct: 499  GIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGL 558

Query: 1348 IGPGGPPGLPGPAGPKGAKGATGPGGP---KGEKGVQGPPGHPGPPGEVIQPLPIQMPKK 1404
             G  G  GL G  G  G KG  GP G     GEKG QGPPG PG PG    P P      
Sbjct: 559  RGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPG---SPGPAGPAGP 615

Query: 1405 TRRSVDGSRLMQEDEAIPTGGAPGSPG 1431
                  G   +Q  + +P  GAPG PG
Sbjct: 616  PGYGPQGEPGLQGTQGVP--GAPGPPG 640



 Score =  149 bits (377), Expect = 2e-35
 Identities = 96/253 (37%), Positives = 121/253 (47%), Gaps = 38/253 (15%)

Query: 270  GPRGLKGEKGEPAVLEPGMLV------EGPPGPEGPAGLIGPPG--------IQGNPGPV 315
            GP G++G  G P +  PG ++       GPPG  G  G  GPPG        I+G+ G +
Sbjct: 1216 GPTGIEGFPGPPGL--PGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSM 1273

Query: 316  GDPGERGPPGRAG---LPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQ 372
            G PG +GPPG AG    PG  GAPG PG    LP   G  G    P V  +         
Sbjct: 1274 GHPGPKGPPGTAGDMGPPGRLGAPGTPG----LPGPRGDPGFQGFPGVKGE--------- 1320

Query: 373  QARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGR 432
                  +G PG +G  G PGP+G  G PG++G+ G L      G  G  G PG+ G +G 
Sbjct: 1321 ------KGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGE 1374

Query: 433  AGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGP 492
             G  G  G  G  G +G  G DG PG PG  G +G+ G++G PGP G DG  G  G+ G 
Sbjct: 1375 PGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGD 1434

Query: 493  RGLPGESGPRGLL 505
             G P     RG +
Sbjct: 1435 SGSPATWTTRGFV 1447


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score =  886 bits (2290), Expect = 0.0
 Identities = 589/1465 (40%), Positives = 675/1465 (46%), Gaps = 286/1465 (19%)

Query: 196  LDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQPHRAQRSPQQQPSRL 255
            L + +  G    + I+  VQ  Y S ++    C GG+     +  P +  R P   P   
Sbjct: 15   LTKSLATGPWSLILILFSVQYVYGSGKKYIGPC-GGRDCSVCHCVPEKGSRGPPGPPG-- 71

Query: 256  HRPQNQEPQSQ----AAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGN 311
                   PQ       A GP GL GEKG      P     G  G +GP G+ G PG+ G 
Sbjct: 72   -------PQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAA-GDKGDKGPTGVPGFPGLDGI 123

Query: 312  PGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAIL 371
            PG  G PG RG PG +G  GS G PG PG    L    G GG    P    ++  +  IL
Sbjct: 124  PGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGAL----GPGGPLGHPGEKGEKGNSVFIL 179

Query: 372  QQAR-----------------LALRGPPGPMGYTGRPG---PLGQPGSPGLKG------- 404
               +                     GP GP GY G PG   P GQPG PGLKG       
Sbjct: 180  GAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVK 239

Query: 405  ----ESGDLGPQGPRGPQ------------------------GLTGPPGKAGRRGRAGAD 436
                + G++G QG  GP                         GL GPPG+ G  G  GA 
Sbjct: 240  GQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESG-IGAK 298

Query: 437  GARGMPGDPGVKGDRGFDGLPGLPGEKGH---------------RGDTGAQGLPGPPG-- 479
            G +G+PG PG +GD G  G PG PG KG                +GD G +G PGPPG  
Sbjct: 299  GEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVL 358

Query: 480  ------------------EDGERGDDGEIGPRGLPGESGPR--GLLGPKGPPGIPGPPGV 519
                                GE GD G  GP GL G  G    G++GP GP G PG PG+
Sbjct: 359  VTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGL 418

Query: 520  RGMDG-PQGPKGSLGPQGEPGPPGQQGTPGTQGLPG---------------------PQG 557
             G  G P  P  + G  G+PG PG  G PG QGLPG                     P G
Sbjct: 419  PGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPG 478

Query: 558  AIGPHGEKG----------PQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPL 607
              GP GEKG          P G PG PG+PG  G  G  G  G  GTKG+ GP G +GP 
Sbjct: 479  GRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPP 538

Query: 608  GYPGPRGVKGVDGIRG---------LKGHKGEKGEDGFPGFKGD---------IGVKGDR 649
            G PG  G  G  G +G         +KGHKGE+G DG PGF G           G KGD 
Sbjct: 539  GLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDP 598

Query: 650  GEVG-----VPGSRGEDGPEGPKGRTGPTGDPGP--PGLMGEKGKLGVPGLPG------- 695
            G  G      PG +G  GP GP G+ GP G PG   PG  GE+G  GVPG PG       
Sbjct: 599  GPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGL 658

Query: 696  -------------YPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQR 742
                         YPGR GP G  G PG  G  G +GA GLSG  G +G  G  G     
Sbjct: 659  KGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIP 718

Query: 743  GPRGATGKSGAKGTSG--GDGPHGPPGERGLPGPQGPNGFPGPK-----GPPGPPGKDGL 795
            GP G  G  G  G  G  G  P GPPG  G PG  G  G PG       GPPG  G  G+
Sbjct: 719  GPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGV 778

Query: 796  PGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGK 855
            PG  G RG+ G  G  GP G PG +G +G  G  G  G  G PGPPG   E+G PG  G+
Sbjct: 779  PGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQ 838

Query: 856  EGTKGDPGPPGAPG---------KDGPAGLRGFPGERGLPGTAGGPGLKGNEGP------ 900
             G  G PG PGAPG           GPAG++G PG  G PG  G PGL G  GP      
Sbjct: 839  PGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGL 898

Query: 901  SGPPGPAGS---------PGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP 951
             GPPGP G          PGERG  G+ G  G  G PG +G  G  G++G+ G KG IGP
Sbjct: 899  PGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGP 958

Query: 952  TGRDGVQGPV---GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPG----PPG 1004
             G +G    +   G PG  GPPG  G  G++G+ G PG +G +G  G +GPPG     PG
Sbjct: 959  PGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPG 1018

Query: 1005 PIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1064
              G  G PG  G  G  G RG  G  G  GD+G  G  GPPG  G+ G  GP G KG+  
Sbjct: 1019 EKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPA 1078

Query: 1065 D-VGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVK 1123
               GP GP G PG  G  G  GA G QG PG  G  G PG  G PG SG PG  G+ G+ 
Sbjct: 1079 SHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMP 1138

Query: 1124 GPRGERGEKGE------SGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG--EGG 1175
            G RG+ GE G+       G PG PGPPG KGP+G  G  G  G  G  G  G  G  + G
Sbjct: 1139 GLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVG 1198

Query: 1176 PRGQDGAKGDRGEDGEPGQPG--SPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGD 1233
            P G  G  G +GE G+PG PG   PGP G+ GPPGP G  GP G  G+ GR     A  D
Sbjct: 1199 PPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGR-----APKD 1253

Query: 1234 PGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQ-QGRPGATGQAGPPGPVGPPGLPG 1292
                G PG  GP GP GP G PGP GL   PGSV   +G PG  G  GPPGP GPPG PG
Sbjct: 1254 IPDPGPPGDQGPPGPDGPRGAPGPPGL---PGSVDLLRGEPGDCGLPGPPGPPGPPGPPG 1310

Query: 1293 LRGDAGAKGEKGHPGLIGLIGP---------------PGEQGEKGDRGLPGPQGSPGQ-- 1335
             +G  G  G+ G  G +G  GP               PG  G KG  GLPGP+G PG   
Sbjct: 1311 YKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPA 1370

Query: 1336 --------------------KGEMGIPGASGPIGPG--GPPGLPGPAGPKGAKGATGPGG 1373
                                +G MG+PG  GP GPG  G PGL G  G  G  G+ GP G
Sbjct: 1371 DVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPG 1430

Query: 1374 PKGEKGVQGPPGHPGPPGEVIQPLP 1398
             KG+ G  G PG PGPPG +  P P
Sbjct: 1431 RKGDTGEDGYPGGPGPPGPIGDPGP 1455



 Score =  827 bits (2137), Expect = 0.0
 Identities = 539/1299 (41%), Positives = 622/1299 (47%), Gaps = 215/1299 (16%)

Query: 335  APGPPGTSLML---PFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRP 391
            A GP    L+L    + +GSG    GP      +    + ++     RGPPGP G  G  
Sbjct: 20   ATGPWSLILILFSVQYVYGSGKKYIGPCGGRDCSVCHCVPEKGS---RGPPGPPGPQGPI 76

Query: 392  GPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDR 451
            GPLG PG  GL GE G    +G RGP G  G  G  G  G  G  G  G+PG PG  G R
Sbjct: 77   GPLGAPGPIGLSGEKG---MRGDRGPPGAAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPR 133

Query: 452  GFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESG--------PRG 503
               G PG+ G  G RGD      PG PG  G  G  G +G  G  GE G         +G
Sbjct: 134  ---GKPGMSGHNGSRGD------PGFPGGRGALGPGGPLGHPGEKGEKGNSVFILGAVKG 184

Query: 504  LLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP--GPQGAIGP 561
            + G +G PG+PG PG  G  GP GP G  G  G  GPPGQ G PG +G P  G +G +G 
Sbjct: 185  IQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGD 244

Query: 562  HGEKGPQGKPG------------LPGMPGSDGPPGHPGKEGPPGTKGNQ--GPSGPQGPL 607
             GE G QG PG              G  G  G PG  G  GPPG KG    G  G +G  
Sbjct: 245  PGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIP 304

Query: 608  GYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGS---------- 657
            G+PGPRG  G  G  G  G KGE G  G PG  G IG KGD G  G PG           
Sbjct: 305  GFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLP 364

Query: 658  -RGEDGPEGPKGRTGPTGD---PGPPGLMGEKGKL-----------GVPGLPGYPGRQG- 701
             +G  G  G  GR G TGD   PGPPGL+G  G+            G PGLPG PG  G 
Sbjct: 365  LKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGI 424

Query: 702  ---PKGSLGFPGFPGASGEKGARGLSGKSGPR------GERGPTGPRGQRGPRGATGKSG 752
               P  + G PG PG+ G  GA GL G  G        G  GP G +G+ GP G  G  G
Sbjct: 425  PGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKG 484

Query: 753  AKGTSG----GDGPHGPPGERGLPGPQGPN------GFPGPKGPPGPPGKDGLPGHPGQR 802
             KG  G      GP GPPG  GLPG QG        G+ G KG PGPPG +G PG PG+ 
Sbjct: 485  EKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKH 544

Query: 803  GE------------------VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGP---- 840
            G                    G +G+ GP GPPG  G  G+ G  G  GE+G PGP    
Sbjct: 545  GASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDH 604

Query: 841  ------------------------------PGPPGEQGLPGTAGKEGTKGD--------- 861
                                          PGPPGE+G PG  G  G +G          
Sbjct: 605  EDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGD 664

Query: 862  --------PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP---PGPAGSP 910
                    PG  G PG DGP G +GFPG +G PG +G  G KG  G  G    PGP G  
Sbjct: 665  TISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFR 724

Query: 911  GERGAAGSGGPIG--PPGRPGPQGPPGAAGEKGVPGEK--GPIGPTGRDGVQGPVGLPGP 966
            G+ G  G GG  G  P G PGP G PG  G+KG+PG+   G +GP G+ G+ G  G+ GP
Sbjct: 725  GDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGP 784

Query: 967  AGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGP 1026
             G PG  G +G  G  G  G KG KG +G  G PG PGP G   + GA G  G+PG  G 
Sbjct: 785  RGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGY 844

Query: 1027 QGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGA 1086
             G  GA G +G  G  GPPGP G++GLPG  G  G     GP G PG PGP G  G  G 
Sbjct: 845  PGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAH---GPPGLPGIPGPFGDDGLPGP 901

Query: 1087 DGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGP 1146
             GP+GP G  G  G PGE+G+PG  G PG +GEPG KG  G  G++G  G  G  GPPG 
Sbjct: 902  PGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGD 961

Query: 1147 KGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGED----------GEPGQPG 1196
            +G       KG PG  G PGD G PGE G +G  G +G RGE           GEPG+ G
Sbjct: 962  EGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKG 1021

Query: 1197 SPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGP----------V 1246
             PGP G  GPPG  G RG  G PG  G QG  G+ G PG  G  G  GP           
Sbjct: 1022 QPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHF 1081

Query: 1247 GPAGPAGKP------------GPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLR 1294
            GP GP G+P            G  GL G+ G  G  GRPG  G +GPPG  G  G+PGLR
Sbjct: 1082 GPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLR 1141

Query: 1295 GDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASG--PIGPGG 1352
            G  G  G+ G  GL G  G PG  G KG  G PG  G  G KG+ G  GASG   +GP G
Sbjct: 1142 GQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPG 1201

Query: 1353 PPGLPGPAGPKGAKGATG--PGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSV- 1409
            P G+PG  G +G  G+ G  P GP+G+KG  GPPG  GPPG      P     +  + + 
Sbjct: 1202 PVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPG------PAGATGRAPKDIP 1255

Query: 1410 DGSRLMQEDEAIPTG--GAPGSPGGLEEIFGSLDSLREE 1446
            D      +    P G  GAPG PG    + GS+D LR E
Sbjct: 1256 DPGPPGDQGPPGPDGPRGAPGPPG----LPGSVDLLRGE 1290



 Score =  815 bits (2106), Expect = 0.0
 Identities = 518/1214 (42%), Positives = 607/1214 (50%), Gaps = 194/1214 (15%)

Query: 275  KGEKGEPAVLEPGML-VEGPPGPEGPAGL--IGPPGIQGNPGPVGDPGERGPPGRAGLPG 331
            KGEKG   +  PGM+ + GPPG +G +G+   G  GI G PGP GDPG  G PG  GL G
Sbjct: 269  KGEKGIKGI--PGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKG 326

Query: 332  SDGAPGPPGT-SLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGR 390
              G  G PG   L+ P       G  GP           +L    L L+GPPG  G+ GR
Sbjct: 327  ELGLVGDPGLFGLIGPKGDPGNRGHPGP---------PGVLVTPPLPLKGPPGDPGFPGR 377

Query: 391  ---PGPLGQPGSPGLKGESGD-----LGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMP 442
                G +G PG PGL G  G+     +GP GP+G  GL G PG+AG  GR   D A G P
Sbjct: 378  YGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRP--DSAPGKP 435

Query: 443  GDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPR 502
            G PG  G      LPG PG +G  G +      G PG  G +G  G  G RG  GE G  
Sbjct: 436  GKPGSPG------LPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNE 489

Query: 503  GLL----GPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGA 558
            GL     GP GPPG PG PG +G  G  G  G LG +G+PGPPG +G PG   LPG  GA
Sbjct: 490  GLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPG---LPGKHGA 546

Query: 559  IGP------------------HGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPG------- 593
             GP                   GE+GP G PG PG PGS G  GH G++G PG       
Sbjct: 547  SGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHED 606

Query: 594  -TKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEV 652
             T G +G  GP GP G  GP G  G+ G  G  G +G  G  G PG +G  G+KG +G+ 
Sbjct: 607  ATPGGKGFPGPLGPPGKAGPVGPPGL-GFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDT 665

Query: 653  --------GVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG---LPGYPGRQG 701
                    G  G  G DGP GPKG  GP G PG  G  G KG+ G PG   +PG PG +G
Sbjct: 666  ISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRG 725

Query: 702  PKGSLGF--------------PGFPGASGEKGARG--LSGKSGPRGERGPTGPRGQRGPR 745
              G  GF              PG PG +G+KG  G    G  GP G+RG +G  G +GPR
Sbjct: 726  DMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPR 785

Query: 746  GATGKSGAKGTSGGDG------PHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHP 799
            G  G  GA+G +G  G      P G  G  G PG  GP G    +G PG PG+ GLPG+P
Sbjct: 786  GDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYP 845

Query: 800  GQRGEVGFQGK---TGPPGP------------PGVVGPQGAAGETGPMGERGHPGPPGPP 844
            G  G  G +G+    GPPGP            PG  GP G  G  GP G+ G PGPPGP 
Sbjct: 846  GSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPK 905

Query: 845  GEQGLPGTAGKEGTKGDPGP---PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPS 901
            G +GLPG  G  G +G PG    PGA G+ G  G+ G PG+RGL G  G  G  G+EG  
Sbjct: 906  GPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEM 965

Query: 902  ------------GPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPG----AAGEKGVPGE 945
                        GPPG  G PGERG  G+ G  G  G PG  GPPG      GEKG PG 
Sbjct: 966  AIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGP 1025

Query: 946  KGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE----HGPPG 1001
             GP GP G  G++G +G PG  G  G  G  G  G  G  G +G KGNKG+     GPPG
Sbjct: 1026 PGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPG 1085

Query: 1002 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKG 1061
            P G  G  G PG  GA GE G  G QG  G+ G  G  G +GPPG  G  G+PG  G+ G
Sbjct: 1086 PKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPG 1145

Query: 1062 ETGDVGPMGP------PGPPGPRGPAGPNGADGPQGPPG--------GVGNLGPPGE--- 1104
            E GD GP G       PGPPG +GP+G  G +G  G  G        G+ ++GPPG    
Sbjct: 1146 EMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGI 1205

Query: 1105 ---KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPG-------------EPGPPGPKG 1148
               KGE G+ GSPGI   PG +G +G  G  G SG PG             +PGPPG +G
Sbjct: 1206 PGLKGERGDPGSPGIS-PPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQG 1264

Query: 1149 PTGDDGPKGNPGPVGFPGD----------------PGPPGEGGPRGQDGAKGDRGEDGEP 1192
            P G DGP+G PGP G PG                 PGPPG  GP G  G  G  G+DG+ 
Sbjct: 1265 PPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQK 1324

Query: 1193 GQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIG-------APGKTGP 1245
            G  G PGP G +G PGP G++G  G PG +G  G  G +G+PG           PG  G 
Sbjct: 1325 GPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGA 1384

Query: 1246 VGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGH 1305
             G  GP G  G  G+RG P   G +G PG  G+ G  G  G PG PG +GD G  G  G 
Sbjct: 1385 PGMRGPEGAMGLPGMRG-PSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGG 1443

Query: 1306 PGLIGLIGPPGEQG 1319
            PG  G IG PG +G
Sbjct: 1444 PGPPGPIGDPGPKG 1457



 Score =  720 bits (1858), Expect = 0.0
 Identities = 454/1082 (41%), Positives = 522/1082 (48%), Gaps = 187/1082 (17%)

Query: 270  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPG-PVGDPGERGPPGRAG 328
            GP GL G  GE      GM+  GPPGP+G  GL G PG  G PG P   PG+ G PG  G
Sbjct: 388  GPPGLLGRPGEACA---GMI--GPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPG 442

Query: 329  LPGSDGAPGPPGTSLM-----------LPFRFGSGGGDKGPVVAAQEAQAQAILQQARLA 377
            LPG+ G  G PG+S++           +  + G  GG +GP    +  +    L      
Sbjct: 443  LPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGG-RGP----KGEKGNEGLCACEPG 497

Query: 378  LRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADG 437
              GPPGP G  GR G  G  G PG  G  GD GP G  GP GL G  G +G  G  GA G
Sbjct: 498  PMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKG 557

Query: 438  ARGMPGDPGVKGDRGFDGLPGLPGEKGHRG---DTGAQGLPGPPG--EDGERGDDGEIGP 492
               +    G KG+RG DG PG PG+ G  G     G +G PGPPG  ED   G  G  GP
Sbjct: 558  DMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGP 617

Query: 493  RGLPGESGP--------RGLLGPKGPPGIPGPPGVRGMDGPQGPKG-----SLGPQGEPG 539
             G PG++GP         G  G +G PG+PG PGVRG DG +G KG     ++   G  G
Sbjct: 618  LGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHG 677

Query: 540  PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQG 599
            PPG  G PG +G PGPQGA G  G  G +G+PG PG     GPPG  G  G PG  G +G
Sbjct: 678  PPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKG 737

Query: 600  --PSGPQGP--------------------LGYPGPRGVKGVDGIRG-------------- 623
              P GP GP                    LG PG RG+ GV GI+G              
Sbjct: 738  SSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPA 797

Query: 624  -------LKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRG----------------- 659
                   LKG KG +G  GFPG  G  G   +RG  G+PG  G                 
Sbjct: 798  GIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQP 857

Query: 660  -EDGPEGPKGRTGPTGDPG------PPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFP 712
             + GP GP G  G  G PG      PPGL G  G  G  GLPG PG +GP+G  GFPGFP
Sbjct: 858  GDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFP 917

Query: 713  GASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGG---------DGPH 763
            G  G+ GA G  G  G  GE+G +G  G RG RGA G  G  G  G           G  
Sbjct: 918  GERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEP 977

Query: 764  GPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPG-HPGQRGEVGFQGKTGPPGPPGVVGP 822
            GPPG+ G PG +G  G PG +G  G PG+ G PG H G+ GE G  G  GPPGPPG  G 
Sbjct: 978  GPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGL 1037

Query: 823  QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP-------GPPGAPGKDGPAG 875
            +G  G  G  G++G PG PGPPG  G+ G  G +G KGDP       GP G PG  G  G
Sbjct: 1038 RGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPG 1097

Query: 876  LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPG 935
              G  GE+GLPG  G  G  G  GP G  GP G PG+ G  G  G  G  G PGP+G  G
Sbjct: 1098 HFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQG 1157

Query: 936  AAGEKGVPGEKGPIGPTGRDGVQG--------------PVGLPGPAGPPGVAGEDGDKGE 981
              G  G PG KGP G  G +G+ G               VG PGP G PG+ GE GD G 
Sbjct: 1158 DPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGS 1217

Query: 982  VG--DPGQKGTKGNKGEHGPPGPPGPIGPVGQ-------PGAAGADGEPGARGPQGHFGA 1032
             G   PG +G KG  G  G  GPPGP G  G+       PG  G  G PG  GP+G  G 
Sbjct: 1218 PGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGP 1277

Query: 1033 ----------KGDEGTRGFNGPPGPIGLQGLPGPSGEKG---ETGDVGPMGPPGPPGPRG 1079
                      +G+ G  G  GPPGP G  G PG  G  G   + G  GP+G PGP GP G
Sbjct: 1278 PGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHG 1337

Query: 1080 PAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGS-------PGIQGEPGVKGPRGERG-- 1130
              GP G  G  GPPG  G  G PG +GEPG           PG+ G PG++GP G  G  
Sbjct: 1338 FPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLP 1397

Query: 1131 ------------------EKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG 1172
                               +G  G PG PGPPG KG TG+DG  G PGP G  GDPGP G
Sbjct: 1398 GMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKG 1457

Query: 1173 EG 1174
             G
Sbjct: 1458 FG 1459



 Score =  640 bits (1651), Expect = 0.0
 Identities = 400/936 (42%), Positives = 459/936 (49%), Gaps = 137/936 (14%)

Query: 242  HRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPA-------VLEPGMLVEGPP 294
            H+ +R P   P          P    +HG  G  GEKG+P            G    GP 
Sbjct: 567  HKGERGPDGPPGF--------PGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPL 618

Query: 295  GPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGG 354
            GP G AG +GPPG+ G PGP   PGERG PG   +PG  G  GP G             G
Sbjct: 619  GPPGKAGPVGPPGL-GFPGP---PGERGHPG---VPGHPGVRGPDGLK-----------G 660

Query: 355  DKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPG---SPGLKGESGDLGP 411
             KG  ++              +   G  GP G+ G PGP G PG   +PGL G  G  G 
Sbjct: 661  QKGDTISCN------------VTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGR 708

Query: 412  QGPRGPQGLTGPPGKAGRRGRAGADGARGMP--GDPGVKGDRGFDGLPGLPGEK--GHRG 467
             G  G   + GPPG  G  G  G  G +G    G PG  G  G +G  G+PG+   GH G
Sbjct: 709  PGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLG 768

Query: 468  DTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQG 527
              G +GL G PG  G RGD G  G  G  G  G  GL GPKG  G  G PGV G  G   
Sbjct: 769  PPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSC 828

Query: 528  PKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPG 587
             +G+ G  G+PG PG  G+PG  G  G  G +GP G  G +G PGLPG PG+ GPPG PG
Sbjct: 829  ERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPG 888

Query: 588  KEGPPGTKGNQGPSGPQGPL------GYPGPRGVKGVDGIRGLKGHKGEKGEDGFP---- 637
              GP G  G  GP GP+GP       G+PG RG  G +G  G KG  GEKG  G P    
Sbjct: 889  IPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRG 948

Query: 638  --GFKGDIGVKGDRGEV------------------GVPGSRGEDGPEGPKGRTGPTGDPG 677
              G KG IG  GD GE+                  G PG RG+ G  G +GR G  G  G
Sbjct: 949  LRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYG 1008

Query: 678  PPGL----MGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER 733
            PPG      GEKG+ G PG PG PG  G +G +GFPG PG  GE G+ G  G SG  G R
Sbjct: 1009 PPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGAR 1068

Query: 734  GPTGPRGQRGPR-GATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGF------PGPKGP 786
            GP G +G      G  G  G  G+ G  G  G  GE+GLPG QGP G       PG  GP
Sbjct: 1069 GPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGP 1128

Query: 787  PGPPGKDGLPGHPGQRGEV------GFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGP 840
            PG PG  G+PG  GQ GE+      G QG  G PGPPG+ GP G+ G  G  G +G  G 
Sbjct: 1129 PGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGT 1188

Query: 841  P--------GPPGEQGLPGTAGKEGTKGDPG--PPGAPGKDGPAGLRGFPGERGLPGTAG 890
                     GPPG  G+PG  G+ G  G PG  PPG  GK GP G    PG  G PG AG
Sbjct: 1189 KGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGP---PGSSGPPGPAG 1245

Query: 891  G----------PGLKGNEGPSGPPGPAGSPGERGAAGSGGPI-GPPGRPGPQGPPGAAGE 939
                       PG  G++GP GP GP G+PG  G  GS   + G PG  G  GPPG  G 
Sbjct: 1246 ATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGP 1305

Query: 940  KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 999
             G PG KG  G  G+DG +GPVG PGP GP G  G  G+KG  G PG+KG  G  G  G 
Sbjct: 1306 PGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGE 1365

Query: 1000 PGPPGPI----------GPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIG 1049
            PGPP  +          G  G  G  GA G PG RGP G     G +G  G +G  G  G
Sbjct: 1366 PGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSG----PGCKGEPGLDGRRGVDG 1421

Query: 1050 LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNG 1085
            + G PGP G KG+TG+ G  G PGPPGP G  GP G
Sbjct: 1422 VPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKG 1457



 Score =  352 bits (904), Expect = 1e-96
 Identities = 240/609 (39%), Positives = 275/609 (45%), Gaps = 114/609 (18%)

Query: 262  EPQSQAAHGPRGLKGEKGEP----AVLEPGMLVEGPPGPEGPAGLIGPPGIQGN---PGP 314
            +P      GP G+KG  G P    A   PG+   G PGP G  GL GPPG +G    PG 
Sbjct: 856  QPGDVGPPGPAGMKGLPGLPGRPGAHGPPGL--PGIPGPFGDDGLPGPPGPKGPRGLPGF 913

Query: 315  VGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQA 374
             G PGERG PG  G PG+ G PG  G S  LP   G  G          E +   I Q+ 
Sbjct: 914  PGFPGERGKPGAEGCPGAKGEPGEKGMS-GLPGDRGLRGAKGAIGPPGDEGEMAIISQKG 972

Query: 375  RLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGP----------QGPRGPQGLTGPP 424
                 GPPG  G+ G  G  G PG  G +GE G  GP          +G  GP G  GPP
Sbjct: 973  TPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPP 1032

Query: 425  GKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQ-GLPGPPGE--- 480
            G  G RG  G  G  G  G+PG  G  GF G+ G  G KG++GD  +  G PGP GE   
Sbjct: 1033 GSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGS 1092

Query: 481  ---------DGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGS 531
                      GE+G  G  GPRG PG  GP G  GP G PG  G PG+RG  G  G  G 
Sbjct: 1093 PGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGP 1152

Query: 532  LGPQGEPGPPG---------------------QQGTPGTQGL-----PGPQGAIGPHGEK 565
             G QG+PG PG                     Q+GT G  GL     PGP G  G  GE+
Sbjct: 1153 RGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGER 1212

Query: 566  GPQGKPGL--PGMPGSDGPPGHPGKEGPPGTKG----------------NQGPSGPQGPL 607
            G  G PG+  PG  G  GPPG PG  GPPG  G                +QGP GP GP 
Sbjct: 1213 GDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPR 1272

Query: 608  GYPGPRGVKG-VDGIRGLKG------------------HKGEKGEDGFPGFKGDIGVKGD 648
            G PGP G+ G VD +RG  G                  +KG  G DG  G KG +G  G 
Sbjct: 1273 GAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGP 1332

Query: 649  RGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLG----VPGLPGYPGRQGPKG 704
            +G  G PG  GE G  GP GR GPTG PGP G  G    +     +PGLPG PG +GP+G
Sbjct: 1333 QGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEG 1392

Query: 705  SLGFPGF--------------PGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGK 750
            ++G PG                G  G  G  G  G  G +G+ G  G  G  GP G  G 
Sbjct: 1393 AMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGD 1452

Query: 751  SGAKGTSGG 759
             G KG   G
Sbjct: 1453 PGPKGFGPG 1461


>gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]
          Length = 1714

 Score =  871 bits (2251), Expect = 0.0
 Identities = 525/1286 (40%), Positives = 647/1286 (50%), Gaps = 117/1286 (9%)

Query: 402  LKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGL-PGLP 460
            L+G  GD GP GP GP G+ GP GK G RG  G  G  G+PG PG KG +G  G  PG P
Sbjct: 487  LRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQP 546

Query: 461  GEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVR 520
               G +GD G  GL GPPG  G++G  G  G  GLPGE G  G  G  G PG PG  G+ 
Sbjct: 547  -VPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLA 605

Query: 521  GMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG---------PQGAIGPHGEKGPQGKP 571
            G +G  GPKG+ G  G PG  GQ G  G +G+PG          QG  G  G++GP G  
Sbjct: 606  GPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLD 665

Query: 572  GLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEK 631
            G PG+ G  GPPG PG  G  G  G  GP+G  GP+G  G +G+ G+ G +G +G  GE 
Sbjct: 666  GSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGEL 725

Query: 632  GEDGFPGFKGDIGV---------KGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLM 682
            GE G+PG KG +G+          G  G+ G PG +G  GP GP+G  G  G PG  G  
Sbjct: 726  GEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPE 785

Query: 683  GEKGKLG---VPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPR 739
            G KG LG    PG PG  G QG +G +G  G  G  G+ G +G +G+ GP G +G  G +
Sbjct: 786  GPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQ 845

Query: 740  GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPN------GFPGPKGPPGPPGKD 793
            G  G  G TG  G  G  G  G  G  GERG PGP GP       G+PGP G PGP G  
Sbjct: 846  GNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPL 905

Query: 794  GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTA 853
            GLPGH G R         GPPG  G  G +G+ G  G +GE+G  G  G  G+QG  G  
Sbjct: 906  GLPGHVGAR---------GPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPH 956

Query: 854  GKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGER 913
            G  G  G+PG  G  GK G  GL G  G+RGLPG    PGL+G +G  GPPG  G  G  
Sbjct: 957  GLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGE---PGLRGLQGDVGPPGEMGMEGPP 1013

Query: 914  GAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA 973
            G  G  G  G PG  G  G  G+ G  G PG +G  G  G +G+QG  GL G  G  G+ 
Sbjct: 1014 GTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLP 1073

Query: 974  GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK 1033
            GEDG+KGE+G PG  G  G  G+ G PGP G +G  GQ G  G  G+ G  GP G  G++
Sbjct: 1074 GEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSR 1133

Query: 1034 GDEGTRGFNGPP------GPIGLQGLPGPSGEKGETGDVGPMGPPGP---PGPRGPAGPN 1084
            G  G  G +GP       G +G  GL GP GE G  G  G  G PGP   PGP+G  G  
Sbjct: 1134 GPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYP 1193

Query: 1085 GAD----GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGE 1140
            G D    GP GP G  G +G  GE+GEPG  G  G  G PG++G  G++G  GE G  GE
Sbjct: 1194 GEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGE 1253

Query: 1141 PGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGP 1200
             G  G +G  G+ G KG PGP G PG PG  G  GP+   G +G  G DG  G PG  GP
Sbjct: 1254 QGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPK---GIQGYHGADGISGNPGKIGP 1310

Query: 1201 TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL 1260
             G+ G P   G RG  G  G  G  G  G KG  G  G+PG  GP G  G  G+PG  G 
Sbjct: 1311 PGKQGLP---GIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGK 1367

Query: 1261 RGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGE 1320
            RG  G+ G QG  G  G  G PG  G  GL G +G  G KG +G  G++G+ GP G  G 
Sbjct: 1368 RGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGH 1427

Query: 1321 KGD------RGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGP 1374
            +G+       G+ GP G  G +GE G  G +GP GP G PG P                 
Sbjct: 1428 RGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPP----------------- 1470

Query: 1375 KGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLE 1434
                   GPPG PGP  ++     IQ   ++  ++        +  +            E
Sbjct: 1471 -------GPPGAPGPRKQMDINAAIQALIESNTALQMESYQNTEVTLIDHS--------E 1515

Query: 1435 EIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRV 1494
            EIF +L+ L   +  ++ P GT+D+PAR C+DL  C  ++ DG+YW+DPN GC  DA  V
Sbjct: 1516 EIFKTLNYLSNLLHSIKNPLGTRDNPARICKDLLNCEQKVSDGKYWIDPNLGCPSDAIEV 1575

Query: 1495 FCNFTAGGETCVTPRDDVTQFSYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPCSGAAR- 1553
            FCNF+AGG+TC+ P   VT+  +       VG VQ+ FL LLS  A   ++  C    R 
Sbjct: 1576 FCNFSAGGQTCLPP-VSVTKLEF------GVGKVQMNFLHLLSSEATHIITIHCLNTPRW 1628

Query: 1554 --------DGPLRLRGANEDELSPETSPYVKEFRDGCQTQQG---RTVLEVRTPVLEQLP 1602
                      P+  +G N       T    K   D C+ Q G   +      T    QLP
Sbjct: 1629 TSTQTSGPGLPIGFKGWNGQIFKVNTLLEPKVLSDDCKIQDGSWHKATFLFHTQEPNQLP 1688

Query: 1603 VLDASFSDLGAPPRRGGVLLGPVCFM 1628
            V++          R+  +    VCF+
Sbjct: 1689 VIEVQKLPHLKTERKYYIDSSSVCFL 1714



 Score =  763 bits (1970), Expect = 0.0
 Identities = 462/1043 (44%), Positives = 525/1043 (50%), Gaps = 72/1043 (6%)

Query: 274  LKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSD 333
            L+G KG+           GPPGP GPAG+ GP    G  GP G PG  G PG  GLPG  
Sbjct: 487  LRGPKGDT----------GPPGPPGPAGIPGP---SGKRGPRGIPGPHGNPGLPGLPGPK 533

Query: 334  GAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGP 393
            G  G PG S   P     G      ++     Q    L+     L G PG  G  G  G 
Sbjct: 534  GPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLK-GHPGLPGLPGEQGIPGFAGN 592

Query: 394  LGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGF 453
            +G PG PG +G +G  G  GP+G QG  G PG+A   G+ G +G RG+   PG++G +GF
Sbjct: 593  IGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEA---GQLGPEGERGI---PGIRGKKGF 646

Query: 454  DGLPGLPGEKGHRGDTGAQGLP------GPPGEDGERGDDGEIGPRGLPGESGPRGLLGP 507
             G  G PG+ G RG  G  G P      GPPG  G RG  G +GP G  G  GP GL G 
Sbjct: 647  KGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGN 706

Query: 508  KGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 567
            KG PGI G  G +G  G  G  G  G +G  G P   G PG +G  GP G  G  G +GP
Sbjct: 707  KGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLP---GPPGMRGKSGPSGQTGDPGLQGP 763

Query: 568  QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGP---QGPLGYPGPRGVKGVDGIRGL 624
             G PG  G PG  G PG  G EGP G  GN+GP GP   +G  G  GP G  G  G RG 
Sbjct: 764  SGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGK 823

Query: 625  KGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGE 684
             G KG  GE G  G KG++G +G+ G++G  G  G  G  G  G  G  G+ G PG +G 
Sbjct: 824  PGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGP 883

Query: 685  KGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGP 744
            +G+ GV G PG PG  GP G LG P      G  GARG  G  GP+G+RG  GP G  G 
Sbjct: 884  QGEKGVMGYPGPPGVPGPIGPLGLP------GHVGARGPPGSQGPKGQRGSRGPDGLLGE 937

Query: 745  RGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGE 804
            +G  G  G KG  G  GPHG  G+ G PG +G  G PG +G PG  G  GLPG PG R  
Sbjct: 938  QGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLR-- 995

Query: 805  VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGP 864
             G QG  GPPG  G+ GP G  GE+G  GE   PG  G  G  G  G  G+ G +G+PG 
Sbjct: 996  -GLQGDVGPPGEMGMEGPPGTEGESGLQGE---PGAKGDVGTAGSVGGTGEPGLRGEPGA 1051

Query: 865  PGAPGKDGPAGLRGFPGERGLP---GTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGP 921
            PG  G  G  GL+G PG RGLP   G  G  GL G  GP G  G  G PG  G  G  G 
Sbjct: 1052 PGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQ 1111

Query: 922  IGPPGRPGPQ---GPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGD 978
             G PG+ G +   GP G  G +G PG+ G  GP G  G +G VG  G  GP G  G  G 
Sbjct: 1112 RGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGY 1171

Query: 979  KGEVGDPGQKGTKGNKGEHGPP-------GPPGPIGPVGQPGAAGADGEPGARGPQGHFG 1031
            +G  G PG  G  G KGE G P       GPPGP G  G  G  G  GEPGA G +GH G
Sbjct: 1172 RGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVG 1231

Query: 1032 AKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQG 1091
              G  G  G  GPPG  G Q   G  G KGE G  G  G  G PGP G  G  G  G  G
Sbjct: 1232 VPGLRGATGQQGPPGEPGDQ---GEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLG 1288

Query: 1092 PPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTG 1151
            P G  G  G  G  G PG+ G PG QG PG+      RG  G +G  G PGPPG KG +G
Sbjct: 1289 PKGIQGYHGADGISGNPGKIGPPGKQGLPGI------RGGPGRTGLAGAPGPPGVKGSSG 1342

Query: 1152 DDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLG 1211
              G  G  GP G  G PG PG  G RG  GA+GD+G  G+PG  G PG  G  G  G  G
Sbjct: 1343 LPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQG 1402

Query: 1212 KRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQG 1271
              GP G  G  G  G  G KG  G  G  G  G  G  GP G+ GP G +G  G  G Q 
Sbjct: 1403 FPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQ- 1461

Query: 1272 RPGATGQAGPPGPVGPPGLPGLR 1294
                 G  G PGP GPPG PG R
Sbjct: 1462 -----GPRGQPGPPGPPGAPGPR 1479



 Score =  715 bits (1846), Expect = 0.0
 Identities = 430/1001 (42%), Positives = 502/1001 (50%), Gaps = 91/1001 (9%)

Query: 263  PQSQAAHGPRGLKGEKGEPAV--------------LEPGMLVEGPPGPEGPAGLIGPPGI 308
            P      GPRG+ G  G P +                PG  V G  G +G +GL+GPPG+
Sbjct: 506  PGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGM 565

Query: 309  QGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--GDKGPVVA----- 361
            QG+ G  G PG  G PG  G+PG  G  G PG     P R G  G  G+ GP  A     
Sbjct: 566  QGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPG----YPGRQGLAGPEGNPGPKGAQGFIG 621

Query: 362  --AQEAQAQAILQQARLALRGPP---------------GPMGYTGRPGPLGQPGSPGLKG 404
               +  Q     ++    +RG                 GP G  G PG +G  G PG  G
Sbjct: 622  SPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPG 681

Query: 405  ESGDLGPQGPRGPQGLTGP---------PGKAGRRGRAGADGARGMPGDPGVKGDRGFDG 455
              G +GP GP GP G+ GP         PG  G +G  G  G  G PG PG KG  G  G
Sbjct: 682  LRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPG 741

Query: 456  LPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPG 515
             PG+ G+ G  G TG  GL GP G  G  G  G+IG  G  G  GP+GLLG +GPPG PG
Sbjct: 742  PPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPG 801

Query: 516  PPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP---GPQGAIGPHGEKGPQGKPG 572
              G +G +GP G  G LGP+G+PG  G  G PG +GL    G QG IG  GE GP G PG
Sbjct: 802  LKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPG 861

Query: 573  LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 632
              GM GS G  G  G  GP       GP G +G +GYPGP GV G  G  GL GH G +G
Sbjct: 862  EVGMTGSIGEKGERGSPGP------LGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARG 915

Query: 633  EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 692
                    G  G KG RG  G  G  GE G +G KG  G  G  GP GL+G+ G  G  G
Sbjct: 916  P------PGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERG 969

Query: 693  LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG 752
              G PG QG  GS G  G P   GE G RGL G  GP GE G  GP G  G  G  G+ G
Sbjct: 970  FQGKPGLQGLPGSTGDRGLP---GEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPG 1026

Query: 753  AK---GTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQG 809
            AK   GT+G  G  G PG RG PG  G  G  G  G  G PG  GLPG  G++GE+G   
Sbjct: 1027 AKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGL-- 1084

Query: 810  KTGPPGPPGVVGPQGAAGET---GPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPG 866
                   PG++GP G +G+T   GP G  G PG  G PG++G  G  G  G  G  GPPG
Sbjct: 1085 -------PGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPG 1137

Query: 867  APGKDGP---AGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGP-- 921
              GK GP    G RG  G  GL G  G PG+ G  G  G PGP+G PG +G  G  G   
Sbjct: 1138 KIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDS 1197

Query: 922  --IGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDK 979
              +GPPG  G  GP G  GE+G PG +G  G  G  G++G  G  GP G PG  GE G K
Sbjct: 1198 TVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLK 1257

Query: 980  GEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1039
            GE G  G KG KG  G  G PG PG  G +G  G  G  G  G  G  G  G  G +G  
Sbjct: 1258 GERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLP 1317

Query: 1040 GFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNL 1099
            G  G PG  GL G PGP G KG +G  G  G  GP G +G  G  G  G +G  G  G+ 
Sbjct: 1318 GIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQ 1377

Query: 1100 GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP 1159
            GP G+ G  G+ G  G+QG  G +G  G +G +G++G  G  GP GP G  G+ GP G  
Sbjct: 1378 GPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGRE 1437

Query: 1160 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGP 1200
            G +G  G  GP GE G RG+ G +G RG+ G PG PG+PGP
Sbjct: 1438 GIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGP 1478



 Score =  421 bits (1082), Expect = e-117
 Identities = 264/641 (41%), Positives = 310/641 (48%), Gaps = 98/641 (15%)

Query: 231  GQRERPQNQQPHRAQRSPQQQPSRLHRPQNQ----EPQSQAAHGPRGLKGEKGEPAVLEP 286
            G R  P +Q P + QR  +     L     Q    E   Q   GP GL G+ G P     
Sbjct: 912  GARGPPGSQGP-KGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNP----- 965

Query: 287  GMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLP 346
                 G  G +G  GL G PG  G+ G  G+PG RG  G  G PG  G  GPPGT     
Sbjct: 966  -----GERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTE---- 1016

Query: 347  FRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGES 406
                   G+ G                    L+G PG  G  G  G +G  G PGL+GE 
Sbjct: 1017 -------GESG--------------------LQGEPGAKGDVGTAGSVGGTGEPGLRGEP 1049

Query: 407  GDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLP------GLP 460
            G  G +G +G  GL G PG  G  G  G  G  G+PG  G  G  G  GLP      G+P
Sbjct: 1050 GAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIP 1109

Query: 461  GEKGHRGDTGAQGLPGPPGEDGERGDDGEI---GPRGLPGESGPRGLLGPKGPPGIPGPP 517
            G++G  G  G +G  GP GE G RG  G+I   GP+G  G  G  G LG  GP G PG P
Sbjct: 1110 GQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIP 1169

Query: 518  GVRGMDGPQGPKGSLGPQGEPGPPGQQ----GTPGTQGLPGPQGAIGPHGE------KGP 567
            G RG  G  GP G  GP+GE G PG+     G PG +G PGP G  G  GE      KG 
Sbjct: 1170 GYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGH 1229

Query: 568  QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH 627
             G PGL G  G  GPPG PG +G  G KG +G  G +G  G PGP G  G+ G++GL G 
Sbjct: 1230 VGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGP 1289

Query: 628  KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 687
            K      G  G+ G  G+ G+ G++G PG +G  G  G  GRTG  G PGPPG+ G    
Sbjct: 1290 K------GIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSS-- 1341

Query: 688  LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 747
                GLPG PG QGPKG  G PG PG  G++G RG  G  GP G+    G +GQ G  G 
Sbjct: 1342 ----GLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGD---PGLKGQPGEYGV 1394

Query: 748  TGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGF 807
             G +G +G  G  GP G  G  G+ GP+GP G  G  GP G  G  G  G  G RGE GF
Sbjct: 1395 QGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGF 1454

Query: 808  QGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQG 848
            +G+TGP GP                  RG PGPPGPPG  G
Sbjct: 1455 RGETGPQGP------------------RGQPGPPGPPGAPG 1477



 Score =  366 bits (940), Expect = e-101
 Identities = 219/511 (42%), Positives = 262/511 (51%), Gaps = 50/511 (9%)

Query: 270  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 329
            G RGL+G+ G P   E GM  EGPPG EG +GL G PG +G+ G  G  G  G PG  G 
Sbjct: 993  GLRGLQGDVGPPG--EMGM--EGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGE 1048

Query: 330  PGSDGAPGPPGTSLMLPFRFGSG----GGDKGPVVAAQEAQAQAILQQARLALRGPPGPM 385
            PG+ G  G  G   +     G G     G+KG              +     + GP G  
Sbjct: 1049 PGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKG--------------EMGLPGIIGPLGRS 1094

Query: 386  GYTGRPGP---LGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMP 442
            G TG PGP   +G PG  G  G+ GD G  GP G  G  GPPGK G+ G  GA G RG  
Sbjct: 1095 GQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAV 1154

Query: 443  GDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI-GPRGLPGESGP 501
            G  G+ G    DG PG+PG +GH+G  G  GLPGP GE G  G+D  + GP G  GE GP
Sbjct: 1155 GHLGLMGP---DGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGP 1211

Query: 502  RGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGP 561
               +G +G  G PG  G +G  G  G +G+ G QG PG PG QG  G +G  G +G  G 
Sbjct: 1212 ---VGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGK 1268

Query: 562  HGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGI 621
             G  GP GKPG+PG+ G  GP G  G  G  G  GN G  GP G  G PG RG  G  G+
Sbjct: 1269 KGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGL 1328

Query: 622  RGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGL 681
             G  G  G KG  G PG  G  G KG++G  G PG +G+ G  G +G  GP GDPG  G 
Sbjct: 1329 AGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQ 1388

Query: 682  MGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSG------------KSGP 729
             GE G  G+ G  G+PG +GP+G  G  G  G  G  G RG +G            ++GP
Sbjct: 1389 PGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGP 1448

Query: 730  RGERG------PTGPRGQRGPRGATGKSGAK 754
            RGE+G      P GPRGQ GP G  G  G +
Sbjct: 1449 RGEKGFRGETGPQGPRGQPGPPGPPGAPGPR 1479



 Score =  193 bits (491), Expect = 1e-48
 Identities = 131/320 (40%), Positives = 147/320 (45%), Gaps = 44/320 (13%)

Query: 266  QAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPG 325
            Q   GP GL G KGE         V GPPGP G  G +G  G +G PG  G  G  G PG
Sbjct: 1175 QGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPG 1234

Query: 326  RAGLPGSDGAPGPPGTS--LMLPFRFGSGG-----GDKGPVVAAQEAQAQAILQQARL-- 376
              G  G  G PG PG      L    GS G     G  GP         Q +L    +  
Sbjct: 1235 LRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQG 1294

Query: 377  -----------------ALRGPPGPMGYTGRPGPLGQPGSPGLKGESG---DLGPQGPRG 416
                               +G PG  G  GR G  G PG PG+KG SG     G QGP+G
Sbjct: 1295 YHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKG 1354

Query: 417  PQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPG 476
             QGL G PG  G+RG  GA G +G  GDPG+KG          PGE G +G TG QG PG
Sbjct: 1355 EQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQ---------PGEYGVQGLTGFQGFPG 1405

Query: 477  PPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQG 536
            P G +G+ G  G  GP+   G  G RG  GP G  GI GP    G  GP+G KG  G  G
Sbjct: 1406 PKGPEGDAGIVGISGPK---GPIGHRGNTGPLGREGIIGP---TGRTGPRGEKGFRGETG 1459

Query: 537  EPGPPGQQGTPGTQGLPGPQ 556
              GP GQ G PG  G PGP+
Sbjct: 1460 PQGPRGQPGPPGPPGAPGPR 1479



 Score =  103 bits (256), Expect = 2e-21
 Identities = 73/188 (38%), Positives = 84/188 (44%), Gaps = 48/188 (25%)

Query: 268  AHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQG---------NPGPVGDP 318
            A GP G+KG  G P    PG+      GP+G  GL G PGIQG         + GP GDP
Sbjct: 1331 APGPPGVKGSSGLPG--SPGI-----QGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDP 1383

Query: 319  GERGPPGR---AGLPGSDGAPGPPGTSLMLPFRFGSGG-----GDKGPVVAAQEAQAQAI 370
            G +G PG     GL G  G PGP G         G  G     G KGP+           
Sbjct: 1384 GLKGQPGEYGVQGLTGFQGFPGPKGPE-------GDAGIVGISGPKGPI----------- 1425

Query: 371  LQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRR 430
                    RG  GP+G  G  GP G+ G  G KG  G+ GPQGPRG  G  GPPG  G R
Sbjct: 1426 ------GHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPR 1479

Query: 431  GRAGADGA 438
             +   + A
Sbjct: 1480 KQMDINAA 1487



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 43/178 (24%), Positives = 85/178 (47%), Gaps = 12/178 (6%)

Query: 66  AQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPVRFLYE 125
           A +  P  ++ P    + F++LT +++     A L ++ +   + QLG++L  P + +  
Sbjct: 88  AYIETPFVKILPVNLGQPFTILTGLQSHRVNNAFLFSIRNKNRL-QLGVQL-LPKKLVVH 145

Query: 126 DQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRV--TRPLPRSARPVL 183
            +        QP     S+ D +WH  A+ ++ QSV++ V+C K+   T  +P       
Sbjct: 146 IRG------KQPAVFNYSVHDEQWHSFAITIRNQSVSMFVECGKKYFSTETIPEV--QTF 197

Query: 184 DTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQP 241
           D++ V   G+   +   FEG V +L I+P  +A+ + C   + +C    + +P+   P
Sbjct: 198 DSNSVFTLGSMNNNSIHFEGIVCQLDIIPSAEASADYCRYVKQQCRQADKYQPETSIP 255


>gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens]
          Length = 1712

 Score =  832 bits (2150), Expect = 0.0
 Identities = 547/1334 (41%), Positives = 634/1334 (47%), Gaps = 216/1334 (16%)

Query: 270  GPRGLKGEKGEPAVL-------------EPGML-VEGPPGPEGPAGLIGPPGIQGNPGPV 315
            GP+G KG+KGEP  L             EPG++  +GPPG  G  G +GP G  G PGP 
Sbjct: 160  GPQGPKGQKGEPYALPKEERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPP 219

Query: 316  GDPGERGPPGRAGL--------PGSDGAPGPPG--TSLMLPFRFGSG--------GGDKG 357
            G PG +G  G  GL         G  G PGP G  +  + P    +G         G+KG
Sbjct: 220  GPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKG 279

Query: 358  PVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGP 417
               +  E   + I  +    + G PG  GY G  G  G PG  G +G  G  GP GPRGP
Sbjct: 280  ---SEGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGP 336

Query: 418  QGLTGPPGKAG-------------RRGRAGADGARGMPGDPGVKGDRGFDGLPGL----- 459
            +G  G PG  G              RG  G  GA+G PG  G  GD G  G PGL     
Sbjct: 337  KGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDG 396

Query: 460  ------PGEKGHRGDTGAQGLP----GPPGEDGERGDDGEIGPRGLPGESGPRGLL---- 505
                  PGE G +G  G  G+P    GPPG DG+RG  G   P GLPG  GP G L    
Sbjct: 397  DQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPG---PPGLPGPPGPDGFLFGLK 453

Query: 506  GPKGPPGIPGPPGVRGMDGPQGPKGSLGP----QGEPGPPGQQGTPGTQGLPGPQGAIGP 561
            G KG  G PG PG  G  GP+G KG  G     +G+    G  G PG +G  G  G  G 
Sbjct: 454  GAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGR 513

Query: 562  HGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGP---SGPQGPLGYPGPRGVKG- 617
             G++G  G+ GLPG PG  G PG+ G  GP G KG+       G +G  G PG  G+KG 
Sbjct: 514  KGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGD 573

Query: 618  --------VDGIRGLKGHKGE--KGEDGFPGFKGDIGVKGDRGEVG-----VPGSRGEDG 662
                    +DG  GL G  G+  KG  G PG+ G  G KG  GE+G     +PG +G+ G
Sbjct: 574  DGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRG 633

Query: 663  PEGPKGRTGPTGDPGPPGLMGEKGKL---------------------------GVPGLPG 695
              G  G  GP G  GPPG  G  G++                           G+PGLPG
Sbjct: 634  FPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPG 693

Query: 696  YPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTG---PRGQRGPRGATGKSG 752
             PG  G KG  G PGF GA G  G RGL G +G  G  GP G   PRG +G  G  G  G
Sbjct: 694  PPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDG 753

Query: 753  AKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTG 812
            + G  G  GP GPPGERGLPG +     PGP+G  G PG+ GL G PG RG  GF+G  G
Sbjct: 754  SPGPIGLPGPDGPPGERGLPG-EVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQG 812

Query: 813  PPG------PPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPG 866
             PG       PG+ GP G  G  GP G  G PG PG  G  GLPG  G+EG  GD G PG
Sbjct: 813  MPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPG 872

Query: 867  APGKDGPAGLRGFPGERG---------------------LPGTAG--------------- 890
              G  GP G++G  G+RG                     +PGT G               
Sbjct: 873  DTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQG 932

Query: 891  GPGLKGNEGPSGPPGPAGS---PGERGAAGSGGPIGPPGRPGPQGPPGAA--GEKGVPGE 945
             PGLKG  G  G  G AG    PG +G AG  G  G  G PGP GPP     G K + GE
Sbjct: 933  MPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGE 992

Query: 946  KGPIGPTG------RDGVQGPVGLPGPAGPPGVAGEDGD----KGEVGDPGQKGTKGNKG 995
            KG  GP G        G+QG  G+PG +G PG+ G  G     KG++G PG  G  G  G
Sbjct: 993  KGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPG 1052

Query: 996  EHGPPGP---PGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE----GTRGFNGPPGPI 1048
              GPPG    PG IG  G  GA G  G  G  G  G FG  GD     G  G  G  G  
Sbjct: 1053 VAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTT 1112

Query: 1049 GLQGLPGPSGEKGETGDVG------PMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPP 1102
            G+ GL G  GEKG  GD+G        G  GPPG +G  G  G  GP G  G +G +G P
Sbjct: 1113 GIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLP 1172

Query: 1103 GEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGP--------PGPKGPTGDDG 1154
            G KG+ G  G+PG+ G PG++G RG  G  G  G PG PG         PGP G  GD G
Sbjct: 1173 GGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPG 1232

Query: 1155 PKGN-PGPVGFPG---DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPL 1210
                 PGPVG PG   D G PGE GP G  G +G  G        G+PG  G  G  G  
Sbjct: 1233 EANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLK 1292

Query: 1211 GKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL------RGLP 1264
            G RGP G PGS    G KG  G+PGA G PG  G  G +GP G+PG  GL      RG  
Sbjct: 1293 GYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQ 1352

Query: 1265 GSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLI----GLIGPPGEQGE 1320
            G +G  G  GA G  GP GP G PG PG  G  GA G  G P  I    G +GP G +G 
Sbjct: 1353 GFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGP 1412

Query: 1321 KGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGV 1380
             G  G  GPQG PG+ G  G PG +GP G GG   +PG  G +G  G  GP G +G  G 
Sbjct: 1413 PGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGR 1472

Query: 1381 QGPPGHPGPPGEVI 1394
             G PG PG PG  +
Sbjct: 1473 PGSPGLPGMPGRSV 1486



 Score =  817 bits (2110), Expect = 0.0
 Identities = 566/1414 (40%), Positives = 650/1414 (45%), Gaps = 253/1414 (17%)

Query: 260  NQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPG 319
            N  P  Q   G +G KG+KGE     PG  V GP G  G  G+ G PG  G PG  G  G
Sbjct: 72   NGPPGLQGFPGLQGRKGDKGERGA--PG--VTGPKGDVGARGVSGFPGADGIPGHPGQGG 127

Query: 320  ERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--GDKGPVVAAQEAQAQAILQQARLA 377
             RG PG  G  G+ G  GP G     P   G  G  G +GP    Q+ +  A+ ++ R  
Sbjct: 128  PRGRPGYDGCNGTQGDSGPQGP----PGSEGFTGPPGPQGP--KGQKGEPYALPKEERDR 181

Query: 378  LRGPPGPMGYT------GRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPP--GKAGR 429
             RG PG  G        GRPG +GQ G  G  G  G  GP GP+G QG  G    G  G 
Sbjct: 182  YRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGE 241

Query: 430  RGRAGADGARGMPGD--------PGV-------KGDRGFDGLPGLPG--EKGHRGDTGAQ 472
            +G  G  G  G+P D         GV       KG++G +G PG+ G   KG  G  G  
Sbjct: 242  KGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFP 301

Query: 473  GLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV------------- 519
            GL G PG  GE+G  G+ G RGL G  GP G  GPKG  G PGPPG+             
Sbjct: 302  GLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGA 361

Query: 520  RGMDGPQGPKGSLGPQGEPGPPGQQGTPG--------TQGLP---GPQGAI--------- 559
            RG  G  G +G  G QGEPG PG  G PG         +GLP   GP+G I         
Sbjct: 362  RGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALY 421

Query: 560  ----GPHGEKGPQGKPGLPGMPGSD----------------GPPGHPGKEGPPGTKGN-- 597
                GP G++GP G PGLPG PG D                G PG PG  GP G KG+  
Sbjct: 422  GGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAG 481

Query: 598  -----QGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF------------- 639
                 +G    +G  G PGP+G  G++G  G KG +G+ G+ G PGF             
Sbjct: 482  ECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAP 541

Query: 640  -----KGD---IGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGE--KGKLG 689
                 KGD   I  KG+RG+ GVPG  G  G +G  GR G  G PG PG  G+  KG  G
Sbjct: 542  GPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPG 601

Query: 690  VPGLPGYPGRQGPKGSLGFP--GFPGASGEKGARGLSGKSGPRGERGPTGPRGQRG---- 743
             PG PG PG +G  G +G P  G PG  G++G  G +G  GP G  GP GP G  G    
Sbjct: 602  DPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDC 661

Query: 744  -----------------PRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP 786
                             P    G  G  G  G  GP G  G RG+PG  G +G PGP+G 
Sbjct: 662  DTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGL 721

Query: 787  PGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHP-------- 838
            PG  G++G PG PG  G  G +G  G PGP G  GP G  G  GP GERG P        
Sbjct: 722  PGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQP 781

Query: 839  ---------------------GPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLR 877
                                 GPPG  G QG+PG  G +G  G PGP G PG  GP GL 
Sbjct: 782  GPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLH 841

Query: 878  GFPGERGLPGTAGGPGLKGNE---GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPP 934
            GFPG  G  G  G PG+ G E   G  G PG  G+PG  G  G  G  G  G  G QG P
Sbjct: 842  GFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHP 901

Query: 935  GAAGEKGV---PGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTK 991
            G+ G KG+   PG  G  G  G  G+ G  G+PG  G PG  G  G+ G  G PG KG  
Sbjct: 902  GSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLA 961

Query: 992  GN---KGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPI 1048
            G    KG  G PGPPGP  PV  PG     GE G  GP G  G  G +G +G  G PG  
Sbjct: 962  GEPGFKGSRGDPGPPGP-PPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLS 1020

Query: 1049 GLQGLPGPSGE-KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1107
            G+ GLPG  G  KG  GD+G  G PG PG  G AGP G  G  G  G  G+ G PG  G 
Sbjct: 1021 GIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGL 1080

Query: 1108 PGESGSPG----------IQGEPGVKGPRGE------RGEKGESGQPGEPGPPGPKGPTG 1151
             GE G+ G          + G PG+KG RG       +G  GE G  G+ G PG  G TG
Sbjct: 1081 YGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTG 1140

Query: 1152 DDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLG 1211
              GP G  G  GFPG  GPPG  G  G+ G  G +G+DG PG PG PG  G  G  G  G
Sbjct: 1141 VQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHG 1200

Query: 1212 KRGPAGSPGSEGR--QGGKGAKGDPGAIGAPGKT----GPVGPAGPAGKPGPDGLRGLPG 1265
              G  G PGS G    G  G  G PG  G PG+     GPVG  G  G  G  G RG PG
Sbjct: 1201 LPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPG 1260

Query: 1266 SVGQQGRPGAT---------------------GQAGPPGPVGPPGLPGLRGDAGAKGEKG 1304
            S G QG PG T                     G  GPPGP G   LPG +GD G  G  G
Sbjct: 1261 SPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPG 1320

Query: 1305 HPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGAS------GPIGPGGPPGLPG 1358
             PG  G  G  G QG  G  GLPG +G  G++G MG  G +      GP GP G PG PG
Sbjct: 1321 TPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPG 1380

Query: 1359 PAGPKGAKGATG--------PG--GPKGEKGVQGPPGHPGPPGEVIQP----LPIQMPKK 1404
              G  GA G  G        PG  GP+G +G  G PG  GP G   +P     P +   +
Sbjct: 1381 APGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQ 1440

Query: 1405 TRRSVDGSRLMQEDEA-------IPTGGAPGSPG 1431
             R  V      + DE        I   GAPG PG
Sbjct: 1441 GRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPG 1474



 Score =  773 bits (1996), Expect = 0.0
 Identities = 527/1293 (40%), Positives = 610/1293 (47%), Gaps = 269/1293 (20%)

Query: 379  RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 438
            RG PGP+G  G  GP G  G PGL+G  GD   +G RG  G+TGP G  G RG +G  GA
Sbjct: 60   RGQPGPVGPQGYNGPPGLQGFPGLQGRKGD---KGERGAPGVTGPKGDVGARGVSGFPGA 116

Query: 439  RGMPGDPGVKGDR---GFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGL 495
             G+PG PG  G R   G+DG  G  G+ G +G  G++G  GPPG  G +G  GE  P  L
Sbjct: 117  DGIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGE--PYAL 174

Query: 496  P--------GESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT- 546
            P        GE G  GL+G +GPPG PG     G  GP G  G  GP G PGP GQQG  
Sbjct: 175  PKEERDRYRGEPGEPGLVGFQGPPGRPGHV---GQMGPVGAPGRPGPPGPPGPKGQQGNR 231

Query: 547  ----------PGTQGLPGPQG--------AIGP----------HGEKGPQGKPGLPGM-- 576
                       G  G PGP G         I P           GEKG +G+PG+ G+  
Sbjct: 232  GLGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISL 291

Query: 577  ---------PGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH 627
                     PG  G PG  G++G PG KG++G  G QGP G  GP+G  G  G  GL  +
Sbjct: 292  KGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAY 351

Query: 628  -------KGEKGEDGFPGFKGDIGVKGDRGEVGVPG-----------SRGEDGPEGPKGR 669
                   KG +G+ GFPG +G+ G +G+ G+ G+PG            RG  G  GPKG 
Sbjct: 352  SPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGF 411

Query: 670  TGPTGDP----GPPGLMGEKGKLGVPGLPGYP-------GRQGPKGSLGFPGFPGASGEK 718
             G  G P    GPPG  G++G  G PGLPG P       G +G KG  GFPG PG+ G +
Sbjct: 412  IGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGAR 471

Query: 719  GARGLSGKSG----PRGERGPTGPRGQRGPR---GATGKSGAKGTSGGDGPHGPPGERGL 771
            G +G  G +G      G+    G  G  GP+   G  G+ G KG  G  G HG PG  GL
Sbjct: 472  GPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGL 531

Query: 772  PGPQGPNGFPGPKGP------------------PGPPGKDGLPGHPGQRGEVGFQGKTGP 813
             G  G  G PGPKG                   PG PG  G  G PG+ G  GF G  GP
Sbjct: 532  KGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGP 591

Query: 814  PGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGP 873
            PG  G+ GP G  G  G  G +G PG  GPPG  GLPG  G+ G  GD G PG PG  GP
Sbjct: 592  PG-DGIKGPPGDPGYPGIPGTKGTPGEMGPPG-LGLPGLKGQRGFPGDAGLPGPPGFLGP 649

Query: 874  AGLRGFPG-----------------ERGLPGTAGG----PGLKGNEGPSGPPGPAGSPGE 912
             G  G PG                 E   PG  GG    PGL G  GP+G  G  G PG 
Sbjct: 650  PGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGF 709

Query: 913  RGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGV 972
             GA G  GP G PG  G +G PG  G  G  G KG +G  G DG  GP+GLPGP GPPG 
Sbjct: 710  AGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGE 769

Query: 973  AG--------EDGDKGEVGDPGQKGTKGNKGEHGPP------GPPGPIGPVGQPGAAGAD 1018
             G        + G +G+ G PGQ G KG  G+ GPP      G PG  G  GQPG  G  
Sbjct: 770  RGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPS 829

Query: 1019 GEPGARGP---------------------QGHFGAKGDEGTRGFNGPPGPIGLQGLPGPS 1057
            G+PG  GP                      G  G  GD G  G  G PGP+G++GL G  
Sbjct: 830  GQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDR 889

Query: 1058 GEKGETGDVGPMGP---------PGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP 1108
            G+ G TG+ G  G          PG PG +G  G  G DG QG PG  G  G PG KGE 
Sbjct: 890  GDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEA 949

Query: 1109 GESGSPGIQ---GEPGVKGPRGE-----------------RGEKGE-------------- 1134
            G  G PG++   GEPG KG RG+                 +GEKG+              
Sbjct: 950  GFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKG 1009

Query: 1135 ----------SGQPGEPGPPGP-KGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAK 1183
                      SG PG PG PG  KG  GD G  G PG  GFPG  GPPG  G  G  G++
Sbjct: 1010 IQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSR 1069

Query: 1184 GDRGEDGEPGQPGSPGPTGE----------NGPPGPLGKRGPAGSPGSEGRQGGKGAKGD 1233
            GD+G  G  G  G  G TG+           G PG  G+RG  G PG +G  G KG +GD
Sbjct: 1070 GDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGD 1129

Query: 1234 PGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGR---PGATGQAGPPGPVGPPGL 1290
             G  G  G TG  GP G  G+ G  GL G PGS G+ GR   PG  G  G PG  G PG 
Sbjct: 1130 IGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGF 1189

Query: 1291 PGLRGDA---GAKGEKGHPGL--------IGLIGPPGEQGEKGDRG-LPGPQGSPGQKGE 1338
            PGLRG     G  G KG PG          G  GPPGE+G+ G+   LPGP G PGQKG+
Sbjct: 1190 PGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGD 1249

Query: 1339 MGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1398
             G PG  GP G  G  G PG   P    GA G  G  G  G++G  G PGPPG    P  
Sbjct: 1250 QGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALP-- 1307

Query: 1399 IQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1431
                        GS+    D   P  GAPG+PG
Sbjct: 1308 ------------GSK---GDTGNP--GAPGTPG 1323



 Score =  756 bits (1951), Expect = 0.0
 Identities = 486/1194 (40%), Positives = 563/1194 (47%), Gaps = 202/1194 (16%)

Query: 266  QAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPG 325
            Q   GPRG KGE G+P          GPPG   PA    P   +G  G  G PG +G PG
Sbjct: 328  QGPDGPRGPKGEAGDP----------GPPGL--PAYSPHPSLAKGARGDPGFPGAQGEPG 375

Query: 326  RAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLAL-RGPPGP 384
              G PG  G PGPPG S+        G GD+   +  +      I      AL  GPPGP
Sbjct: 376  SQGEPGDPGLPGPPGLSI--------GDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGP 427

Query: 385  MGYTGRPGPLGQPGSP-------GLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAG-AD 436
             G  G PGP G PG P       GLKG  G  G  G  G  G  GP G  G  G     +
Sbjct: 428  DGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTE 487

Query: 437  GARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLP 496
            G   + G PG+ G +GF G+ G PG KG RGD G  GLPG PG  G  G+ G  GP+G  
Sbjct: 488  GDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAK 547

Query: 497  GESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQ--QGTPGTQGLPG 554
            G+S      G +G PG+PG PG++G DG  G  G  G  G PGPPG   +G PG  G PG
Sbjct: 548  GDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPG 607

Query: 555  PQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS------------- 601
              G  G  GE GP G  GLPG+ G  G PG  G  GPPG  G  GP+             
Sbjct: 608  IPGTKGTPGEMGPPGL-GLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVK 666

Query: 602  -----------------GPQGPLGYPGPRGVKGVDGIRGL------------KGHKGEKG 632
                             GP+G  G PGP G  G  G+RG+            +G  G+ G
Sbjct: 667  RAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAG 726

Query: 633  EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGP-------------------- 672
             +GFPG  G IG +G +G VG+PG  G  GP G  G  GP                    
Sbjct: 727  REGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGD 786

Query: 673  ------------TGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGS---------LGFPGF 711
                         GD GPPG  G +G  G+PGL G PG  GP G           GFPG 
Sbjct: 787  AGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGA 846

Query: 712  PGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGL 771
            PG  G  G  G+ G+ G  G+RG  G  G  GP G  G SG +G +G  G  G PG  G 
Sbjct: 847  PGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGF 906

Query: 772  PGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGP 831
             G  G  G PG KG  G PG DG  G PG +G  GF G  G  G  G+ G +G AGE G 
Sbjct: 907  KGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGF 966

Query: 832  MGERGHPGPPGPP--------------------------GEQGLPGTAGKEGTKGDPGPP 865
             G RG PGPPGPP                          G +G+ G  G  G  G PG P
Sbjct: 967  KGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLP 1026

Query: 866  GAPGK----------DGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGA 915
            G PG            G  GL GFPG  G PG  G PG  G+ G  G PG AG  GE GA
Sbjct: 1027 GRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGA 1086

Query: 916  AGSGGPIGP----PGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPG 971
             G  G IG     PGRPG +G  G     G+PG KG     G  G +G +G PG  G  G
Sbjct: 1087 TGDFGDIGDTINLPGRPGLKGERGTT---GIPGLKGFF---GEKGTEGDIGFPGITGVTG 1140

Query: 972  VAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFG 1031
            V G  G KG+ G PG  G  G++GE G  G PG  G  G PGA G  G PG RG +G  G
Sbjct: 1141 VQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHG 1200

Query: 1032 AKGDEGTRGFNGPPGP--IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGP 1089
                 GT+GF G PG    G  G PGP GE+G+ G+   +  PGP G  G  G  GA G 
Sbjct: 1201 L---PGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTL--PGPVGVPGQKGDQGAPGE 1255

Query: 1090 QGPPGGVGNLGPPG------EKGEPGESGSPGIQGEPGVKGPRGE------RGEKGESGQ 1137
            +GPPG  G  G PG        G PG+ G+PGI G  G +GP G        G KG++G 
Sbjct: 1256 RGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGN 1315

Query: 1138 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGE------GGPRGQDGAKGDRGEDGE 1191
            PG PG PG KG  GD GP+G PG  G PG+ GP GE       GP G  G +G +G  G+
Sbjct: 1316 PGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGD 1375

Query: 1192 PGQPGSPGPTGENG----------PPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPG 1241
            PG PG+PG  G  G           PG +G +G  G PG+ G  G +G  G+PG  GAPG
Sbjct: 1376 PGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPG 1435

Query: 1242 KTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRG 1295
            K GP G  G +  P   G RG  G +G Q   G  GQ G PG  G PGLPG+ G
Sbjct: 1436 KAGPQGRGGVSAVP---GFRGDEGPIGHQ---GPIGQEGAPGRPGSPGLPGMPG 1483



 Score =  752 bits (1942), Expect = 0.0
 Identities = 494/1219 (40%), Positives = 568/1219 (46%), Gaps = 208/1219 (17%)

Query: 270  GPRGLKGEKGEPAV-----LEPGMLVEGPPGPEGPAGLIGPPGI----------QGNPGP 314
            G  GL GEKG P       L+     +GP GP+G AG  GPPG+          +G  G 
Sbjct: 305  GYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGD 364

Query: 315  VGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQA 374
             G PG +G PG  G PG  G PGPPG S+        G GD+   +  +      I    
Sbjct: 365  PGFPGAQGEPGSQGEPGDPGLPGPPGLSI--------GDGDQRRGLPGEMGPKGFIGDPG 416

Query: 375  RLALRG-PPGPMGYTGRPGPLGQPGSPG-------LKGESGDLGPQGPRGPQGLTGPPGK 426
              AL G PPGP G  G PGP G PG PG       LKG  G  G  G  G  G  GP G 
Sbjct: 417  IPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGW 476

Query: 427  AGRRGRAGA-DGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERG 485
             G  G     +G   + G PG+ G +GF G+ G PG KG RGD G  GLPG PG  G  G
Sbjct: 477  KGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPG 536

Query: 486  DDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQ-- 543
            + G  GP+G  G+S      G +G PG+PG PG++G DG  G  G  G  G PGPPG   
Sbjct: 537  NIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGI 596

Query: 544  QGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSG- 602
            +G PG  G PG  G  G  GE GP G  GLPG+ G  G PG  G  GPPG  G  GP+G 
Sbjct: 597  KGPPGDPGYPGIPGTKGTPGEMGPPGL-GLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGT 655

Query: 603  -----------------------------PQGPLGYPGPRGVKGVDGIRGL--------- 624
                                         P+G  G PGP G  G  G+RG+         
Sbjct: 656  PGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGG 715

Query: 625  ---KGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTG------- 674
               +G  G+ G +GFPG  G IG +G +G VG+PG  G  GP G  G  GP G       
Sbjct: 716  PGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGE 775

Query: 675  -------------------------DPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLG-- 707
                                     D GPPG  G +G  G+PGL G PG  GP G  G  
Sbjct: 776  VLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLY 835

Query: 708  -------FPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGD 760
                   FPG PG  G  G  G+ G+ G  G+RG  G  G  GP G  G SG +G +G  
Sbjct: 836  GPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFT 895

Query: 761  GPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVV 820
            G  G PG  G  G  G  G PG KG  G PG DG  G PG +G  GF G  G  G  G+ 
Sbjct: 896  GEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIP 955

Query: 821  GPQGAAGETGPMGERGHPGPPGPP--------------------------GEQGLPGTAG 854
            G +G AGE G  G RG PGPPGPP                          G +G+ G  G
Sbjct: 956  GLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPG 1015

Query: 855  KEGTKGDPGPPGAPGK----------DGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPP 904
              G  G PG PG PG            G  GL GFPG  G PG  G PG  G+ G  G P
Sbjct: 1016 IPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAP 1075

Query: 905  GPAGSPGERGAAGSGGPIGP----PGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGP 960
            G AG  GE GA G  G IG     PGRPG +G  G  G   +PG KG  G     G +G 
Sbjct: 1076 GRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTG---IPGLKGFFG---EKGTEGD 1129

Query: 961  VGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGE 1020
            +G PG  G  GV G  G KG+ G PG  G  G++GE G  G PG  G  G PGA G  G 
Sbjct: 1130 IGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGF 1189

Query: 1021 PGARGPQGHFGAKGDEGTRGFNGPPGPI--GLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1078
            PG RG +G  G  G   T+GF G PG    G  G PGP GE+G+ G+   +  PGP G  
Sbjct: 1190 PGLRGIRGLHGLPG---TKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTL--PGPVGVP 1244

Query: 1079 GPAGPNGADGPQGPPGGVGNLGPPGE------KGEPGESGSPGIQGEPGVKGPRGERGE- 1131
            G  G  GA G +GPPG  G  G PG        G PG+ G+PGI G  G +GP G  G  
Sbjct: 1245 GQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSA 1304

Query: 1132 -----KGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGG---PRGQDGAK 1183
                 KG++G PG PG PG KG  GD GP+G PG  G PG+ GP GE G     G  GA 
Sbjct: 1305 ALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAV 1364

Query: 1184 GDRGEDGEPGQPGSPGPTGENGPPGPLG-KRGPAGSPGSEGRQGGKGAKGDPGAIGAPGK 1242
            GDRG  G  G PG PG  G  G PG  G  +  A  PG+ G QG +G  G      APG+
Sbjct: 1365 GDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPG------APGE 1418

Query: 1243 TGPVGPAGPAGKPGPDGLRGLPGSVGQQGR------PGATGQAGP---PGPVGPPGLPGL 1293
             GP GP      PG  G RG PG  G QGR      PG  G  GP    GP+G  G PG 
Sbjct: 1419 MGPQGP------PGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGR 1472

Query: 1294 RGDAGAKGEKGHPGLIGLI 1312
             G  G  G  G    IG +
Sbjct: 1473 PGSPGLPGMPGRSVSIGYL 1491



 Score =  618 bits (1594), Expect = e-176
 Identities = 407/1028 (39%), Positives = 473/1028 (46%), Gaps = 178/1028 (17%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 322
            P S  A GP+G KG+ GE    E    ++G PG  GP G  G  G  G  G  GDPG+ G
Sbjct: 465  PGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHG 524

Query: 323  PPGRAGL---PGSDGAPGPPGT-----SLMLPFRFGSGG--------GDKGPVVAAQEAQ 366
             PG  GL   PG+ GAPGP G      ++      G  G        GD G         
Sbjct: 525  LPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDG 584

Query: 367  AQAILQQARLALRGPPGPMGYTGRPGPLGQPGS--------PGLKGESGDLGPQGPRGPQ 418
               +       ++GPPG  GY G PG  G PG         PGLKG+ G  G  G  GP 
Sbjct: 585  FPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPP 644

Query: 419  GLTGPPGKAGRRGR------------------------AGADGARGMPGDPGVKGDRGFD 454
            G  GPPG AG  G+                         G  G  G+PG PG  G +G  
Sbjct: 645  GFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLR 704

Query: 455  GLPGL------PGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPK 508
            G+PG       PG +G  GD G +G PGPPG  G RG  G +G  G  G  GP GL GP 
Sbjct: 705  GIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPD 764

Query: 509  GPP--------------------GIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPG 548
            GPP                    G+PG PG++G+ G +GP G  G QG PG PG +G P 
Sbjct: 765  GPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQP- 823

Query: 549  TQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPL- 607
              GLPGP G  G +G  G  G PG PG  G  G PG PG+EG PG +G+ G +G  GP+ 
Sbjct: 824  --GLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVG 881

Query: 608  -----------------GYPGPRGVKGVDGIRGLKGHKGE---------------KGEDG 635
                             G+PG  G KG+DG+ G  G KG+               KG  G
Sbjct: 882  MKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPG 941

Query: 636  FPGFKGDI------GVKGDRGEVGVPGSRGEDGPEGP--------KGRTGPTGDPGPPGL 681
            FPG KG+       G+KG  GE G  GSRG+ GP GP        K   G  GD GP GL
Sbjct: 942  FPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGL 1001

Query: 682  MGEKGKLGVPGLPGYPGR-------------QGPKGSL------GFPGFPGASGEKGARG 722
             G  G  G+ G+PG PG              +G KG +      G PGFPG +G  G  G
Sbjct: 1002 KGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITG 1061

Query: 723  LSGKSGPRGERGPTGPRGQRGPRGATGKSGAKG-TSGGDGPHGPPGERGLPGPQGPNGFP 781
              G  G RG++G  G  G  G  GATG  G  G T    G  G  GERG  G  G  GF 
Sbjct: 1062 FPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFF 1121

Query: 782  GPKGP------PGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGER 835
            G KG       PG  G  G+ G PG +G+ GF G TGPPG  G +G  G  G  G  G  
Sbjct: 1122 GEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWP 1181

Query: 836  GHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGA-----PGKDGPAGLRGFPGERG-LPGTA 889
            G PG PG PG +G+ G  G  GTKG PG PG+     PG  GP G RG PGE   LPG  
Sbjct: 1182 GAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPV 1241

Query: 890  GGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPI 949
            G PG KG++G  G  GP GSPG +G  G   P    G PG +G PG  G KG  G  GP 
Sbjct: 1242 GVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPP 1301

Query: 950  GPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP---GQKGTKGNKGEHGPPGPPGPI 1006
            G     G +G  G PG  G PG  G  GD G  G P   G  G KG +GE G  G  GP 
Sbjct: 1302 GSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPT 1361

Query: 1007 GPVGQPGAAGADGEPGARGPQGHFGA-------------KGDEGTRGFNGPPGPIGLQGL 1053
            G VG  G  G  G+PG  G  G  GA              G  G +G  GPPG  G  G 
Sbjct: 1362 GAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGP 1421

Query: 1054 PGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGS 1113
             GP GE G  G  G  GP G  G     G  G +GP      +G+ GP G++G PG  GS
Sbjct: 1422 QGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGP------IGHQGPIGQEGAPGRPGS 1475

Query: 1114 PGIQGEPG 1121
            PG+ G PG
Sbjct: 1476 PGLPGMPG 1483



 Score =  612 bits (1579), Expect = e-175
 Identities = 407/1007 (40%), Positives = 475/1007 (47%), Gaps = 185/1007 (18%)

Query: 595  KGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF---KGDIGVKGDRGE 651
            KG +G  GP GP GY GP G++G  G   L+G KG+KGE G PG    KGD+G +G  G 
Sbjct: 57   KGGRGQPGPVGPQGYNGPPGLQGFPG---LQGRKGDKGERGAPGVTGPKGDVGARGVSGF 113

Query: 652  VGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFP-- 709
             G  G  G  G  GP+GR G  G  G  G  G +G  G  G  G PG QGPKG  G P  
Sbjct: 114  PGADGIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYA 173

Query: 710  ----------GFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGG 759
                      G PG  G  G +G  G+ G  G+ GP G  G+ GP G  G  G +G + G
Sbjct: 174  LPKEERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQG-NRG 232

Query: 760  DGPHGPPGERGLPGPQGPNGFP---------------------GPKGPPGPP-------- 790
             G +G  GE+G  G  GPNG P                     G KG  G P        
Sbjct: 233  LGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLK 292

Query: 791  GKDGLPGHPGQRGEVGFQGKTGPPGPP---GVVGPQGAAGETGPMGERGHPGPPGPP--- 844
            G++G+ G PG RG  G  G+ G PG     G+ G QG  G  GP GE G PGPPG P   
Sbjct: 293  GEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYS 352

Query: 845  ----------GEQGLPGTAGKEGTKGDPGPPGAPGK--------------DGPAGLRGFP 880
                      G+ G PG  G+ G++G+PG PG PG                G  G +GF 
Sbjct: 353  PHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFI 412

Query: 881  GERGLPGTAGG-PGLKGNEGPSGPPGPAGSPGERG-AAGSGGPIGPPGRPGPQGPPGAAG 938
            G+ G+P   GG PG  G  GP GPPG  G PG  G   G  G  G  G PG  G PGA G
Sbjct: 413  GDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARG 472

Query: 939  EKGVPGEKGPIGPT-GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKG-------- 989
             KG  G+ G    T G + ++G  GLPGP G  G+ GE G KG+ GDPGQ G        
Sbjct: 473  PKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLK 532

Query: 990  ----------------------TKGNKGEHGPPGPPGPIGPVGQPGAAGADGEP------ 1021
                                  TKG +G+ G PG PG  G  G PG  G DG P      
Sbjct: 533  GVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPP 592

Query: 1022 --GARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG 1079
              G +GP G  G  G  GT+G  G  GP GL GLPG  G++G  GD G  GPPG  GP G
Sbjct: 593  GDGIKGPPGDPGYPGIPGTKGTPGEMGPPGL-GLPGLKGQRGFPGDAGLPGPPGFLGPPG 651

Query: 1080 PAG------------------------PNGADGPQGPPGGVGNLGPPGEKGEPGESGSPG 1115
            PAG                        P    GP+G PG  G  GP G KG  G  G  G
Sbjct: 652  PAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAG 711

Query: 1116 IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGG 1175
              G PG +G  G+ G +G  G PG  GP G KG  G  GP G+PGP+G PG  GPPGE G
Sbjct: 712  ADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERG 771

Query: 1176 PRGQ--DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGD 1233
              G+      G RG+ G PGQPG  G  G+ GPPG  G +G  G PG +G+ G  G  G 
Sbjct: 772  LPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQ 831

Query: 1234 PGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGL 1293
            PG  G PG  G   P  P G+ GP GL G+PG  G  G  G  G  G PGPVG  GL G 
Sbjct: 832  PGLYGPPGLHG--FPGAP-GQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGD 888

Query: 1294 RGDAGAKGEKGH---PGLIGLIGPPGEQGEKGDRGLPGP---QGSPGQKGEMGIPGASGP 1347
            RGDAG  GE+GH   PG  G+ G PG  G KGDRG PG    QG PG KG  G PG+ G 
Sbjct: 889  RGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGE 948

Query: 1348 IGPGGPPGLPGPAGPKGAKGATGPGGP--------------KGEKGVQGPPGHPGPPGEV 1393
             G  G PGL G AG  G KG+ G  GP              KGEKG +GP G  G  G  
Sbjct: 949  AGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLG-- 1006

Query: 1394 IQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSL 1440
                         + + G   +     IP  G PG PG ++ + G +
Sbjct: 1007 ------------AKGIQGMPGIPGLSGIP--GLPGRPGHIKGVKGDI 1039



 Score =  498 bits (1281), Expect = e-140
 Identities = 331/793 (41%), Positives = 377/793 (47%), Gaps = 121/793 (15%)

Query: 743  GPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQR 802
            G R  +G        GG G  GP G +G  GP G  GFPG +G  G  G+ G PG  G +
Sbjct: 43   GGRDCSGGCQCYPEKGGRGQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPK 102

Query: 803  GEVG------FQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKE 856
            G+VG      F G  G PG PG  GP+G  G  G  G +G  GP GPPG +G  G  G +
Sbjct: 103  GDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQ 162

Query: 857  GTKGDPGPP------------GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPP 904
            G KG  G P            G PG+ G  G +G PG  G  G  G  G  G  GP GPP
Sbjct: 163  GPKGQKGEPYALPKEERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPP 222

Query: 905  GPAGSPGERGAA--GSGGPIGPPGRPGPQGPPGAA------------------GEKGVPG 944
            GP G  G RG    G  G  G  G+PGP G P                     GEKG  G
Sbjct: 223  GPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEG 282

Query: 945  EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG 1004
            E G I      G +G +G PG  G PG++GE       G PGQKG++G  G  GP GP G
Sbjct: 283  EPG-IRGISLKGEEGIMGFPGLRGYPGLSGEK------GSPGQKGSRGLDGYQGPDGPRG 335

Query: 1005 PIGPVGQPG-------------AAGADGEPGARGPQGHFGAKGDEGTRGFNGPPG-PIG- 1049
            P G  G PG             A GA G+PG  G QG  G++G+ G  G  GPPG  IG 
Sbjct: 336  PKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGD 395

Query: 1050 ---LQGLPGPSGEKGETGDVGPM----GPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPP 1102
                +GLPG  G KG  GD G      GPPGP G RGP GP G  GP GP G +  L   
Sbjct: 396  GDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGL--- 452

Query: 1103 GEKGEPGESGSPGIQGEPGVKGPRGERGEKGE----------SGQPGEPGP--------- 1143
              KG  G +G PG+ G PG +GP+G +G+ GE           G PG PGP         
Sbjct: 453  --KGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGE 510

Query: 1144 PGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGD------RGEDGEPGQPGS 1197
            PG KG  GD G  G P   GFPG  G PG  G  G  GAKGD      +GE G+PG PG 
Sbjct: 511  PGRKGDRGDPGQHGLP---GFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGV 567

Query: 1198 PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGP 1257
            PG  G++G PG  G  G  G PG  G  G KG  GDPG  G PG  G  G  GP G  G 
Sbjct: 568  PGMKGDDGSPGRDGLDGFPGLPGPPG-DGIKGPPGDPGYPGIPGTKGTPGEMGPPGL-GL 625

Query: 1258 DGLRGLPGSVGQQGRPGATGQAGPPGPVGPPG-----------LPGLRGDAGAKGEKGHP 1306
             GL+G  G  G  G PG  G  GPPGP G PG           + G R +A   G  G P
Sbjct: 626  PGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGP 685

Query: 1307 -GLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGA 1365
             GL GL GPPG  G KG RG+PG  G+ G  G  G+PG +G  G  GPPG  GP G KGA
Sbjct: 686  KGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGA 745

Query: 1366 KGATGPG---GPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP 1422
             G  GP    GP G  G  GPPG  G PGEV+   P            G + +  D   P
Sbjct: 746  VGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPP 805

Query: 1423 ----TGGAPGSPG 1431
                + G PG PG
Sbjct: 806  GFRGSQGMPGMPG 818



 Score =  254 bits (648), Expect = 6e-67
 Identities = 183/490 (37%), Positives = 214/490 (43%), Gaps = 108/490 (22%)

Query: 1038 TRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVG 1097
            T GF       G++    P G +  +G        G  G  GP GP G +   GPPG  G
Sbjct: 23   TVGFLAQSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQGYN---GPPGLQG 79

Query: 1098 NLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK---------G 1148
              G  G KG+ GE G+PG+ G  G  G RG  G  G  G PG PG  GP+         G
Sbjct: 80   FPGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNG 139

Query: 1149 PTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGD------RGEDGEP------GQPG 1196
              GD GP+G PG  GF G PGP G  G +G+  A         RGE GEP      G PG
Sbjct: 140  TQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERDRYRGEPGEPGLVGFQGPPG 199

Query: 1197 SPGPTGENGPPGPLGKRGPAGSPGSEGRQGGK-----GAKGDPGAIGAPGKTG------- 1244
             PG  G+ GP G  G+ GP G PG +G+QG +     G KG+ G +G PG  G       
Sbjct: 200  RPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSDTLH 259

Query: 1245 PV--------------GPAGPAGKPGP--------------DGLRGLPGSVGQQGRPGAT 1276
            P+              G  G  G+PG                GLRG PG  G++G PG  
Sbjct: 260  PIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQK 319

Query: 1277 GQAGPPGPVGPPGLPGLRGDAG----------------AKGEKGHPGLIGLIGPPGEQGE 1320
            G  G  G  GP G  G +G+AG                AKG +G PG  G  G PG QGE
Sbjct: 320  GSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGE 379

Query: 1321 KGDRGLPGPQGSPGQKGEM--GIPGASGPIG----------PGGPPGLPGPAGPKGAKGA 1368
             GD GLPGP G     G+   G+PG  GP G           GGPPG  G  GP G  G 
Sbjct: 380  PGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGL 439

Query: 1369 TGPGGP-------KGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAI 1421
             GP GP       KG KG  G PG PG PG        + PK  +      R  + DEAI
Sbjct: 440  PGPPGPDGFLFGLKGAKGRAGFPGLPGSPG-------ARGPKGWKGDAGECRCTEGDEAI 492

Query: 1422 PTGGAPGSPG 1431
               G PG PG
Sbjct: 493  K--GLPGLPG 500



 Score =  244 bits (623), Expect = 5e-64
 Identities = 165/409 (40%), Positives = 194/409 (47%), Gaps = 54/409 (13%)

Query: 270  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGN------PGPVGDPGERGP 323
            GP GLKG+ G P +        GPPG +G  G IG PG +G+      PG  G PG RG 
Sbjct: 1143 GPPGLKGQTGFPGLT-------GPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGI 1195

Query: 324  PGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPG 383
             G  GLPG+ G PG PG+ +          GD G                      GPPG
Sbjct: 1196 RGLHGLPGTKGFPGSPGSDIH---------GDPG--------------------FPGPPG 1226

Query: 384  PMGYTGR----PGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGAR 439
              G  G     PGP+G PG    KG+ G  G +GP G  GL G PG       +GA G +
Sbjct: 1227 ERGDPGEANTLPGPVGVPGQ---KGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDK 1283

Query: 440  GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 499
            G PG  G+KG RG  G PG     G +GDTG  G PG PG  G  GD G   P+G PG  
Sbjct: 1284 GAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSG---PQGRPGVF 1340

Query: 500  GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAI 559
            G  G  GP+G  G  G  G  G  G +GPKG  G  G PG PG  G PG  G+P  + A+
Sbjct: 1341 GLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIP-QKIAV 1399

Query: 560  GPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVD 619
             P G  GPQG+ G PG PG  GP G PG+ G  G  G  GP G  G    PG RG +G  
Sbjct: 1400 QP-GTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPI 1458

Query: 620  GIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKG 668
            G +G  G +G  G  G PG  G  G     G + V  S+ +  P  P G
Sbjct: 1459 GHQGPIGQEGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVG 1507


>gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo
            sapiens]
          Length = 1691

 Score =  805 bits (2078), Expect = 0.0
 Identities = 548/1395 (39%), Positives = 640/1395 (45%), Gaps = 270/1395 (19%)

Query: 270  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPG---- 325
            G  GLKGE+G P +L P     GP G +GP G+ G  GI G PG  G PG RGPPG    
Sbjct: 71   GLSGLKGERGFPGLLGP----YGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGC 126

Query: 326  -----RAGLPGSDGAPG---PPGTS---------LMLPFRFGSGGGDKG-PVVAAQEAQA 367
                   G PG DG PG   PPG           ++ P  F    GD G P +       
Sbjct: 127  NGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQ 186

Query: 368  QAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGL-----KGESGDLGPQGPRGPQGLTG 422
             A      +   GPPG  G  G PGPLG  G+ GL     KG  GD+G  GP GP   TG
Sbjct: 187  GAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTG 246

Query: 423  -------PPGKAGRRGRAGADGARGMPGDPGV--------KGDRGFDGLPGLPGEKGHRG 467
                   P GK G +G  G  G  G+ G PG         KG++G  G+PGLPG +G  G
Sbjct: 247  ELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMG 306

Query: 468  DTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPK--------------GPPGI 513
              G QG PG  G+ G  G  G  G +G+ G+ G  GL GP               G PG+
Sbjct: 307  SEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGV 366

Query: 514  PGPPGVRGMDGPQGPKG---------------SLGPQGEPGPPGQQGTPGT--------- 549
            PG PG++G +G QG +G               +LGPQG PG  G QG PG          
Sbjct: 367  PGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLP 426

Query: 550  --QGLPGPQGAIGP--------------------HGEKGPQGKPGLPGMPGSDG------ 581
               GLPGP G  GP                     GE+GP+G  GL G+ G  G      
Sbjct: 427  GRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDG 486

Query: 582  ------PPGHPGKEGP---------PGTKGNQGPSGPQGPLGYPG---------PRGVKG 617
                  PPG PG  GP          G +G++G  G QGP G PG         P+G KG
Sbjct: 487  GVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKG 546

Query: 618  V---------------DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDG 662
                             G +G +G  GE G+DG PG  G  G+ GD G+ G PG +G  G
Sbjct: 547  EPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQ-GFPGEKGLPG 605

Query: 663  PEGPKGRTGPTGDPG--------PPGLMGEKGKLGVPGLPGYPGRQG---------PKGS 705
              G KG  GP G PG        P GL G+KGK G+PG  G PG +G           G 
Sbjct: 606  LPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGP 665

Query: 706  LGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRG------------PRGATGKSGA 753
             GFPG PG  G KG+RGL G  G  G  G  G  G  G            PRG  G  G 
Sbjct: 666  SGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGF 725

Query: 754  KGTSGGDGPHGPPGERGLPGPQGPNG--FPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKT 811
             G  G DG  G  G  GLPG +G  G  F    G PG  G  GL GH G  G+ G  G  
Sbjct: 726  PGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLK 785

Query: 812  GPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKD 871
            G  G PG++GP+G  G  G  G+ G PG PG  G  G+ G +G  G  G PG  G PGK 
Sbjct: 786  GVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKK 845

Query: 872  GPAGLRGFPG---ERGLPGTAG---GPGLKGNEGPSGPPGPAGSP---GERGAAGSGGPI 922
            G  G +G PG   ++GLPG  G    PGL G +G  G PG AG P   G +G  GS G +
Sbjct: 846  GTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFV 905

Query: 923  GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQG---------PVGLPGPAGPPG-- 971
            G PG PG  G PG  G KG+PG  G +GP+GR G  G         PVG+P P  P    
Sbjct: 906  GFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNL 965

Query: 972  -VAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPG----AAGADGEPGARGP 1026
             + G+ G +G  G  G  G +G+KGE G PGPPG  G  G PG     +G  G PG  G 
Sbjct: 966  WLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGI 1025

Query: 1027 QGHFGAKGDEGTRGFNGPPGPIGLQG------LPGPSGEKGETGDVGP-MGPPGPPGPRG 1079
            +G  G KG  G  GF G PG  G QG      LPG SG  G  GD G  +   G PGP+G
Sbjct: 1026 RGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKG 1085

Query: 1080 PAGPNGADGPQGPPGGVGNLGPPGEKGEPGE---SGSPGIQGEPGVKGPRGERGEKGESG 1136
              G +G  G +G  G +GN+G PG KGE G+   SG  G+ G PG  G  G RGE G  G
Sbjct: 1086 QPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPG 1145

Query: 1137 QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAK-----------GD 1185
              G  G  GP G  G  GPKG PG  G  G  G PG  G  G  G             G 
Sbjct: 1146 SSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGP 1205

Query: 1186 RGEDGEPG----QPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPG 1241
            +GE G PG     PG PG  G+ G  G  G +GPAG PG+ G        G PG  G PG
Sbjct: 1206 KGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPG 1265

Query: 1242 KTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKG 1301
              G  G  GPAG PGP G     G  G  G PG  G  GP G  G PG  GL G+ G KG
Sbjct: 1266 LDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKG 1325

Query: 1302 EKGHPGLIGL---IGPPGEQGEKGDRGLPGPQGSPGQKGE-------------------- 1338
             +G PG +G    +GPPG+ G  G +G  GP+GS G +G+                    
Sbjct: 1326 MRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLP 1385

Query: 1339 --------MGIPGASGPI---GPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHP 1387
                     G PGA GP+   G  G PG+PG  GP G  G  G  G  G  G+QGPPG  
Sbjct: 1386 GIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFE 1445

Query: 1388 GPPGEVIQPLPIQMP 1402
            G PG   Q  P  MP
Sbjct: 1446 GAPG---QQGPFGMP 1457



 Score =  800 bits (2066), Expect = 0.0
 Identities = 542/1356 (39%), Positives = 635/1356 (46%), Gaps = 242/1356 (17%)

Query: 269  HGPRGLKGEKGEPAVLE----PGMLVEGPPGPEGPAGLIGPPGIQGN---PGPVGDPGER 321
            +GP+G KG  G P  L     PG    G PGP GP GL G  G QG    PGP G PG  
Sbjct: 88   YGPKGDKGPMGVPGFLGINGIPGH--PGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLL 145

Query: 322  GPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKG-PVVAAQEAQAQAILQQARLALRG 380
            GPP   GLPG  G+ G P   ++ P  F    GD G P +        A      +   G
Sbjct: 146  GPP---GLPGQKGSKGDP---VLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAG 199

Query: 381  PPGPMGYTGRPGPLGQPGSPGL-----KGESGDLGPQGPRGPQGLTG-------PPGKAG 428
            PPG  G  G PGPLG  G+ GL     KG  GD+G  GP GP   TG       P GK G
Sbjct: 200  PPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKG 259

Query: 429  RRGRAGADGARGMPGDPGV--------KGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGE 480
             +G  G  G  G+ G PG         KG++G  G+PGLPG +G  G  G QG PG  G+
Sbjct: 260  SKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGK 319

Query: 481  DGERGDDGEIGPRGLPGESGPRGLLGP--------------KGPPGIPGPPGVRGMDGPQ 526
             G  G  G  G +G+ G+ G  GL GP               G PG+PG PG++G +G Q
Sbjct: 320  KGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQ 379

Query: 527  GPK---------------GSLGPQGEPGPPGQQGT-----------PGTQGLPGPQGAIG 560
            G +               G+LGPQG PG  G QG            PG  GLPGP G  G
Sbjct: 380  GLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPG 439

Query: 561  P--------------------HGEKGPQGKPGLPGMPG------------SDGPPGHPGK 588
            P                     GE+GP+G  GL G+ G            + GPPG PG 
Sbjct: 440  PPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGP 499

Query: 589  EGP---------PGTKGNQGPSGPQGPLGYP---------GPRGVKGV------------ 618
             GP          G +G++G  G QGP G P         GP+G KG             
Sbjct: 500  PGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGD 559

Query: 619  ---DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGP--- 672
                G +G +G  GE G+DG PG  G  G+ GD G+ G PG +G  G  G KG  GP   
Sbjct: 560  RGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQ-GFPGEKGLPGLPGEKGHPGPPGL 618

Query: 673  -----TGDPGPPGLMGEKGKLGVPGLPGYPGRQ---------GPKGSLGFPGFPGASGEK 718
                  G PGP GL G+KGK G+PG  G PG +         G  G  GFPG PG  G K
Sbjct: 619  PGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPK 678

Query: 719  GARGLSGKSGPRGERGPTGPRGQ------------RGPRGATGKSGAKGTSGGDGPHGPP 766
            G+RGL G  G  G  G  G  G              GPRG  G  G  G  G DG  G  
Sbjct: 679  GSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMI 738

Query: 767  GERGLPGPQGPNG--FPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQG 824
            G  GLPG +G  G  F    G PG  G  GL GH G  G+ G  G  G  G PG++GP+G
Sbjct: 739  GSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKG 798

Query: 825  AAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG--- 881
              G  G  G+ G PG PG  G  G+ G +G  G  G PG  G PGK G  G +G PG   
Sbjct: 799  ERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIV 858

Query: 882  ERGLP---GTAGGPGLKGNEGPSGPPGPAGSP---GERGAAGSGGPIGPPGRPGPQGPPG 935
            ++GLP   G  G PGL G +G  G PG AG P   G +G  GS G +G PG PG  G PG
Sbjct: 859  KKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPG 918

Query: 936  AAGEKGVPGEKGPIGPTGRDGV---------QGPVGLPGPAGPPG---VAGEDGDKGEVG 983
              G KG+PG  G +GP+GR G           GPVG+P P  P     + G+ G +G  G
Sbjct: 919  TRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAG 978

Query: 984  DPGQKGTKGNKGEHGPPGPPGPIGPVGQP----GAAGADGEPGARGPQGHFGAKGDEGTR 1039
              G  G +G+KGE G PGPPG  G  G P    G +G  G PG  G +G  G KG  G  
Sbjct: 979  SNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGIT 1038

Query: 1040 GFNGPPGPIGLQ------GLPGPSGEKGETGDVG-PMGPPGPPGPRGPAGPNGADGPQGP 1092
            GF G PG  G Q      GLPG SG  G  GD G  +   G PGP+G  G +G  G +G 
Sbjct: 1039 GFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGR 1098

Query: 1093 PGGVGNLGPPGEKGEPGE---SGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGP 1149
             G +GN+G PG KGE G+   SG  G+ G PG  G  G RGE G  G  G  G  GP G 
Sbjct: 1099 DGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGS 1158

Query: 1150 TGDDGPK------------GNPGPVGFPGDPGP--PGEGGPRGQDGAKGDRGEDG-EPGQ 1194
             G  GPK            G PG  G  G PGP   G  GP G  G KG++G  G   G 
Sbjct: 1159 PGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGA 1218

Query: 1195 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1254
            PG PG  G+ G  G  G +GPAG PG+ G        G PG  G PG  G  G  GPAG 
Sbjct: 1219 PGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGP 1278

Query: 1255 PGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL--- 1311
            PGP G     G  G  G PG  G  GP G  G PG  GL G+ G KG +G PG +G    
Sbjct: 1279 PGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGK 1338

Query: 1312 IGPPGE------QGEKGDRGLPGPQGSPGQ----------KGEMGIPGASGPIGPGGPPG 1355
            +GPPG+      +G+ G RG  G QG PGQ           G +G+PG  G  G  G PG
Sbjct: 1339 VGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPG 1398

Query: 1356 LPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1391
              GP G +G+KG  G  G  G  G+ GPPG  G PG
Sbjct: 1399 AQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPG 1434



 Score =  792 bits (2045), Expect = 0.0
 Identities = 545/1379 (39%), Positives = 637/1379 (46%), Gaps = 250/1379 (18%)

Query: 275  KGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPG------PVGDPGERGPPGRAG 328
            KG +G P  +     ++GP GP+G  G  G  G++G  G      P G  G++GP G  G
Sbjct: 46   KGARGRPGPIG----IQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPG 101

Query: 329  LPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYT 388
              G +G PG PG             G +GP         Q  +        G PGP GY 
Sbjct: 102  FLGINGIPGHPGQP-----------GPRGPPGLDGCNGTQGAV--------GFPGPDGY- 141

Query: 389  GRPGPLGQPGSPGLKGESGD-----------LGPQGPRGPQGLTGP---PGKAGRRGRAG 434
              PG LG PG PG KG  GD            G  G  G  G+TGP   PG  G  G AG
Sbjct: 142  --PGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAG 199

Query: 435  ADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGE----------R 484
              G +G PG PG  G  G  GL G  GEKG +GD G  G  GPP   GE          +
Sbjct: 200  PPGLQGPPGPPGPLGPDGNMGL-GFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKK 258

Query: 485  GDDGEIGPRGLPGESGPRGL--LGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPG 542
            G  GE GP+G PG SGP G   LG  G  G  G  G+ G+ GP+GP GS G Q   GPPG
Sbjct: 259  GSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQ---GPPG 315

Query: 543  QQGTPGTQGLPGPQGAIGPHGEKGPQGKPG-----------LPGMPGSDGPPGHPGKEGP 591
            QQG  GT G PG  G  G  G+KG  G PG           + G PG  G PG PG +G 
Sbjct: 316  QQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGD 375

Query: 592  PGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG------------------- 632
             G +G +GPSG  G     G  G  G  G  GLKG +G  G                   
Sbjct: 376  EGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPP 435

Query: 633  ------------------EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTG 674
                              E GFPG +G+ G KG+ G  G+ G  G    +G    TGP G
Sbjct: 436  GPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPG 495

Query: 675  DPGPP---GLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARG---LSGKSG 728
            +PGPP   GL+G  G  G  G  G  G QGP G+ G  G  G SG KG +G   LS   G
Sbjct: 496  EPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQG 555

Query: 729  PRGERGPTGPRGQRGPRGATGKSGAKGTSG-----GDGPHGPPGERGLPGPQGPNGFPGP 783
              G+RG +G +G RG  G  GK G  G  G     GDG  G PGE+GLPG  G  G PGP
Sbjct: 556  MPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGP 615

Query: 784  KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAA------GETGPMGERGH 837
             G PG    +GLPG PG RG  G +GK G PG  G+ G +G        G  GP G  G 
Sbjct: 616  PGLPG----NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGT 671

Query: 838  PGPPGPPGEQGLPGTAGK---EGTKGDPGPPGA---------PGKDGPAGLRGF---PGE 882
            PG PGP G +GLPGT G+    G+KG+PG PG          PG  G  GL GF   PG+
Sbjct: 672  PGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGK 731

Query: 883  RGLPGTAGGPGLKGNEGPSGP-----------------------PGPAGSPGERGAAGSG 919
             GLPG  G PGL G++G +G                         G +G PG +G  G  
Sbjct: 732  DGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKP 791

Query: 920  GPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDK 979
            G +GP G  G  G PG  G+ G PG  GP G  G+ G+ G  G PG +G PG  G  G K
Sbjct: 792  GLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKK 851

Query: 980  GEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1039
            G  G   +KG  G KG  G PG  G  G  G PG AG     G +G +G  G  G  G  
Sbjct: 852  GPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIP 911

Query: 1040 GFNGPPGPIGLQGLPGPS------------GEKGETGDVGPMGPPGP------------P 1075
            G  G PG  GL+G+PG +            GEKG+ G+ GP+G P P             
Sbjct: 912  GLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDK 971

Query: 1076 GPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG----ESGSPGIQGEPGVKGPRGERGE 1131
            G +G AG NG  GP+G  G  G  GPPG  G PG      G  G  G PG  G RG  G 
Sbjct: 972  GSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGL 1031

Query: 1132 KGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGE-------GGPRGQDGAKG 1184
            KG SG  G PG PG  G  G  G  G PG  G PG  G  G+        GP+GQ G  G
Sbjct: 1032 KGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESG 1091

Query: 1185 DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1244
             +G  G  G  G+ G  G  G  G +G  G  G PG+ G  G  G +G+PG  G+ G  G
Sbjct: 1092 FKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQG 1151

Query: 1245 PVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKG 1304
             +GP G  G  GP G  G PG  G  G PG  G  G PGP    G+PG  G  G KGEKG
Sbjct: 1152 AIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGP-SITGVPGPAGLPGPKGEKG 1210

Query: 1305 HPGL-IGLIGPPGEQGEKGDRGLPGPQ------------------------GSPGQKGEM 1339
            +PG+ IG  G PG +G+KGDRG PG Q                        G PG  GE 
Sbjct: 1211 YPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGER 1270

Query: 1340 GIPGASGPIGPGGP------------PGLPGPAGPKGAKGATGPGGPKGE---KGVQGPP 1384
            G PG +GP GP GP            PG+PGP GPKG +G  G  G  GE   KG++G P
Sbjct: 1271 GRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEP 1330

Query: 1385 GHPGPPGEVIQPLPIQMP-KKTRRSVDGSRLMQEDEA-IPTGGA---PGSPGGLEEIFG 1438
            G  G PG+V  P     P  K +    GS  +Q D    PT  A   P  P GL  I G
Sbjct: 1331 GFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDG 1389



 Score =  730 bits (1884), Expect = 0.0
 Identities = 475/1124 (42%), Positives = 548/1124 (48%), Gaps = 126/1124 (11%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 322
            P  +   G +GL+G  G P +      + G PG  GP G  G  G QGNPG     G  G
Sbjct: 370  PGLKGDEGIQGLRGPSGVPGL----PALSGVPGALGPQGFPGLKGDQGNPGRT-TIGAAG 424

Query: 323  PPGRAGLPGSDGAPGPPG----TSLMLPFRFGSGG--GDKGPV----VAAQEAQAQAILQ 372
             PGR GLPG  G PGPP     T  +     G  G  G++GP     +   +  +     
Sbjct: 425  LPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCAC 484

Query: 373  QARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGR 432
               +   GPPG  G  G  G +G PG  G +G+ G  G QGP G  GL GP G +G +G+
Sbjct: 485  DGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGK 544

Query: 433  AGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGP 492
             G      + G PG +GD G  G  G+ GE G  G  G  GLPG PG+ G+         
Sbjct: 545  KGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQ--------- 595

Query: 493  RGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGL 552
             G PGE G  GL G KG PG PG PG  G+ G  GP+G  G +G+ G PGQQG PG++G+
Sbjct: 596  -GFPGEKGLPGLPGEKGHPGPPGLPG-NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGI 653

Query: 553  PGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSG----PQGPLG 608
              P    G +G  G  G PG PG  GS G PG PG+ G  G+KG  G  G    P+ P G
Sbjct: 654  TLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELP-G 712

Query: 609  YPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGD--RGEVGVPGSRGEDGPEGP 666
            +PGPRG KG+ G  GL G  G  G  G PG  G  G  GD    E G PG +G  G  G 
Sbjct: 713  FPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGH 772

Query: 667  KGRTGPTGDPG------PPGLMGEKGKLGVPGLPGY------PGRQGPKGSLGFPGFPGA 714
            KG  G +G PG       PGL+G KG+ G PG PG       PG  GP G  G  G PGA
Sbjct: 773  KGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGA 832

Query: 715  SGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGP 774
             G  G  G  GK G RG++GP G   ++G  G  G  G  G  G  G  G PG  GLP  
Sbjct: 833  PGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPAL 892

Query: 775  QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 834
             GP G  G  G  G PG  GLPG PG RG  G  G TG       +GP G AG  G  G+
Sbjct: 893  SGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGK------MGPSGRAGTPGEKGD 946

Query: 835  RGHPGPPGPP---------------------GEQGLPGTAGKEGTKGDPGPPGAPGKDGP 873
            RG+PGP G P                     G  G PG  G +G  G PGPPG PG  G 
Sbjct: 947  RGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGL 1006

Query: 874  AGL----RGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPG 929
             G+     G PG  G  G  G PGLKG+ G +G PG  G  G +G  GS G  G  G PG
Sbjct: 1007 PGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPG 1066

Query: 930  PQGP-------PGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 982
             +G         G+ G KG PGE G  G  GRDG+ G +G PG  G  G  G  GD G  
Sbjct: 1067 LKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLP 1126

Query: 983  GDPGQKGTKGNKGEHGPPGPPG---PIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1039
            G PG  G  G +GE G PG  G    IGP+G PG  G  G PG  G  G  G  G +GT 
Sbjct: 1127 GAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTH 1186

Query: 1040 GFNGPP--GPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGP---PG 1094
            G  GP   G  G  GLPGP GEKG  G +G +G PG PG RG  G  G  G QGP   PG
Sbjct: 1187 GTPGPSITGVPGPAGLPGPKGEKGYPG-IG-IGAPGKPGLRGQKGDRGFPGLQGPAGLPG 1244

Query: 1095 GVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERG------EKGESGQPGEPGPPGPKG 1148
              G   P    G+PG+ G PG+ GE G  GP G  G       +G++G PG PG PGPKG
Sbjct: 1245 APGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKG 1304

Query: 1149 PTGDDG---------------PKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1193
            P GD G                +G PG +G PG  GPPG+ G  G  G  G RG  G  G
Sbjct: 1305 PKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQG 1364

Query: 1194 QPGSPGPTGE--NGPPGPLGKRGPAGSPG---SEGRQGGKGAKGDPGAIGAPGKTGPVGP 1248
             PG   PT E    PPGPLG  G  G PG     G QG  G +G  G  G PGK      
Sbjct: 1365 DPGQT-PTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKD----- 1418

Query: 1249 AGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG 1292
             GP+G PGP G  G PG  G QG PG  G  G  GP G PG+PG
Sbjct: 1419 -GPSGLPGPPGALGDPGLPGLQGPPGFEGAPGQQGPFGMPGMPG 1461



 Score =  690 bits (1780), Expect = 0.0
 Identities = 476/1268 (37%), Positives = 553/1268 (43%), Gaps = 304/1268 (23%)

Query: 461  GEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVR 520
            GEK +    G Q   G      E+G  G  GP G+ G +GP+G  G  G  G+ G  G  
Sbjct: 23   GEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFP 82

Query: 521  GMDGPQGPKGSLGPQ------------GEPGPPGQQGTPGTQGLPGPQGAIG-------- 560
            G+ GP GPKG  GP             G PG PG +G PG  G  G QGA+G        
Sbjct: 83   GLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYP 142

Query: 561  ---------------------PHGEKGPQGKPGLPGMPGSDGP---PGHPGKEGPPGTKG 596
                                 P   KG +G PGLPG+ G  GP   PG PG  GP G  G
Sbjct: 143  GLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPG 202

Query: 597  NQGPSGPQGP--------LGYPGPRGVKGVDGI-------------------RGLKGHKG 629
             QGP GP GP        LG+ G +GVKG  G+                   +G KG KG
Sbjct: 203  LQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKG 262

Query: 630  EKGEDGFPGFKGDIGVK--GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 687
            E G  GFPG  G  G    G  GE G  G +G  G  GP+G  G  G  GPPG  G+KG 
Sbjct: 263  EPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGT 322

Query: 688  LGVPGLPGYPGRQGPKGSLGF-----------------------PGFPGASGEKGARGLS 724
            LG PGL G+ G +G KG +G                        PG PG  G++G +GL 
Sbjct: 323  LGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLR 382

Query: 725  GK---------SGPRGERGPTGPRGQRGPRGATGKS--GAKGTSGGDGPHGPPGERGLPG 773
            G          SG  G  GP G  G +G +G  G++  GA G  G DG  GPPG  G P 
Sbjct: 383  GPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPS 442

Query: 774  P--------------------QGPNGF------------------------PGPKGPPGP 789
            P                    QGP G                         PG  GPPGP
Sbjct: 443  PEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGP 502

Query: 790  PGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE------RGHPGPPGP 843
             G  GLPG  G RG+ G  G  GP G PG+VGP G +G  G  GE      +G PG  G 
Sbjct: 503  WGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGD 562

Query: 844  PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGT------AGGPGLKGN 897
             G QG  G  G+ G  G PG PG PG  G  G +GFPGE+GLPG        G PGL GN
Sbjct: 563  SGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGG-QGFPGEKGLPGLPGEKGHPGPPGLPGN 621

Query: 898  EGPSGPPGPAGSPGERG---------------------AAGSGGPIGPPGRPGPQGPPGA 936
             G  G PGP G PG++G                       GS GP G PG PG  GP G+
Sbjct: 622  -GLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGS 680

Query: 937  AGEKGVPGEKGPIGPTGRDGVQGPV------GLPGPAGP------PGVAGEDGDKGEVGD 984
             G  G PG+ G  G  G  G  G V      G PGP G       PG+ G+DG  G +G 
Sbjct: 681  RGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGS 740

Query: 985  PGQKGTKGNKG-----EHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1039
            PG  G+KG  G     E+G PG  G  G  G  G  G  G PG +G  G  G  G +G R
Sbjct: 741  PGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGER 800

Query: 1040 GFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNL 1099
            G  G PG +G  G PG SG  G  G  G  G PG PG  G  G  G  G +GPPG +   
Sbjct: 801  GSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKK 860

Query: 1100 GPPGEKGEP---------GESGSPGIQGEPGVKGPRGERGEKGESGQPGEP--------- 1141
            G PG KG P         G  GSPG+ G P + GP+GE+G  G  G PG P         
Sbjct: 861  GLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTR 920

Query: 1142 ------------GPPGPKGPTGDDGPKGNPGPVGFP------------GDPGPPGEGGPR 1177
                        GP G  G  G+ G +GNPGPVG P            GD G  G  G  
Sbjct: 921  GLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSN 980

Query: 1178 GQDGAKGDRGEDGEPGQPGSPGP----------TGENGPPGPLGKRGP------------ 1215
            G  G +GD+GE G PG PG PG           +G+ GPPG +G RG             
Sbjct: 981  GFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGF 1040

Query: 1216 AGSPGSEGRQGGKGAKGDPGAIGAPGKTGP-------VGPAGPAGKPGPDGLR------- 1261
             G PG  G QG +G+ G PGA G PG  G         G  GP G+PG  G +       
Sbjct: 1041 PGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDG 1100

Query: 1262 -----GLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG 1316
                 G PG+ G+ G+ G +G  G PG  G PG+ G+RG+ G  G  GH G IG +G PG
Sbjct: 1101 LIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPG 1160

Query: 1317 EQGEKGDRGLPGPQGSPGQKGEMGIPGASGP--IGPGGPPGLPGPAGPK-------GAKG 1367
              G KG  G PG  G  G  G  G  G  GP   G  GP GLPGP G K       GA G
Sbjct: 1161 LIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAPG 1220

Query: 1368 ATGPGGPKGEK---GVQGPPGHPGPPGEVIQPLPIQMP-KKTRRSVDGSRLMQEDEAIPT 1423
              G  G KG++   G+QGP G PG PG  +  L    P    R  +DG R          
Sbjct: 1221 KPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGER-----GRPGP 1275

Query: 1424 GGAPGSPG 1431
             G PG PG
Sbjct: 1276 AGPPGPPG 1283



 Score =  562 bits (1448), Expect = e-159
 Identities = 369/899 (41%), Positives = 437/899 (48%), Gaps = 130/899 (14%)

Query: 270  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPA------GLIGPPGIQGNPGPVGDPGERGP 323
            GPRGL G+KG+  +  PG   +G PG +G        G  GP G  G PG  G  G RG 
Sbjct: 628  GPRGLPGDKGKDGL--PGQ--QGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGL 683

Query: 324  PGRAGLPGSDGAPGPPGTS--LMLPFRFGSGG--GDKG----PVVAAQEAQAQAI----- 370
            PG  G PGS G+ G PG+   + LP   G  G  G+KG    P +  ++     I     
Sbjct: 684  PGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGL 743

Query: 371  ---------LQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLT 421
                     +  A     G  G  G TG  G LG  G PGLKG  G  G  GP+G +G  
Sbjct: 744  PGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSP 803

Query: 422  GPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGA---------- 471
            G PG+ G+ G  G+ G  G+ G  G+ G  GF G+ G PG+KG RG  G           
Sbjct: 804  GTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLP 863

Query: 472  --QGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPK 529
              +GLPG PG  G +G  G  G  GLP  SGP+G  G  G  G PG PG+ G+ G +G K
Sbjct: 864  GLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLK 923

Query: 530  GSLGPQGEPGPPGQQGTP---GTQGLPGPQGAIGPH---------GEKGPQGKPGLPGMP 577
            G  G  G+ GP G+ GTP   G +G PGP G   P          G+KG QG  G  G P
Sbjct: 924  GIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFP 983

Query: 578  GSDGPPGHPGKEGPPGTKGNQG-PSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF 636
            G  G  G  G+ GPPG  G  G P   +G  G PGP G     GIRGL G KG  G  GF
Sbjct: 984  GPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFM---GIRGLPGLKGSSGITGF 1040

Query: 637  PGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRT-------GPTGDPGPPGLMGEKGKLG 689
            PG  G+ G +G RG  G+PG+ G  G +G  G+T       GP G PG  G  G KG+ G
Sbjct: 1041 PGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDG 1100

Query: 690  VPGLPGYPGRQGPKGSLGF---------PGFPGASGEKGARGLSGKSGPRGERGPTGPRG 740
            + G  G+PG +G  G +G          PGFPG +G +G  GL G SG +G  GP G  G
Sbjct: 1101 LIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPG 1160

Query: 741  QRGPR---------GATGKSGAKGTSGGDGPH--GPPGERGLPGPQGPNGFPGPKGPPGP 789
              GP+         G  G  G KGT G  GP   G PG  GLPGP+G  G+PG     G 
Sbjct: 1161 LIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGI--GIGA 1218

Query: 790  PGKDGLPGHPGQRGEVGFQGKTGPPGPPG------VVGPQGAAGETGPMGERGHPGPPGP 843
            PGK GL G  G RG  G QG  G PG PG      + G  G  G  G  GERG PGP GP
Sbjct: 1219 PGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGP 1278

Query: 844  PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 903
            PG    PG +  +G  GDPG PG PG  GP G +G PG  GLPG  G  G++G  G  G 
Sbjct: 1279 PGP---PGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGT 1335

Query: 904  PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ---GP 960
            PG  G PG+ G  G  G  GP G  G QG PG               PT  + VQ   GP
Sbjct: 1336 PGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQT-------------PTA-EAVQVPPGP 1381

Query: 961  VGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGE 1020
            +GLPG  G PG+ G+ G +G VG  G KG  G  G+ GP G PGP      PGA G  G 
Sbjct: 1382 LGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGP------PGALGDPGL 1435

Query: 1021 PGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG 1079
            PG +GP G  GA G +         GP G+ G+PG S   G T          PP P G
Sbjct: 1436 PGLQGPPGFEGAPGQQ---------GPFGMPGMPGQSMRVGYTLVKHSQSEQVPPCPIG 1485



 Score =  544 bits (1402), Expect = e-154
 Identities = 382/975 (39%), Positives = 438/975 (44%), Gaps = 202/975 (20%)

Query: 651  EVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGV------PGLPGYPGRQGPKG 704
            E+   G +    P G +  +G        G  G  G +G+       G  G  G  G KG
Sbjct: 18   ELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKG 77

Query: 705  SLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHG 764
              GFPG  G  G KG +G  G  G  G  G  G  GQ GPRG  G  G  GT G  G  G
Sbjct: 78   ERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPG 137

Query: 765  PPGERGLPGPQG--------------PNGFPGPKGPPGPPGKDGL------PGHPGQRGE 804
            P G  GL GP G              P  F G KG PG PG DG+      PG PG  G 
Sbjct: 138  PDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGP 197

Query: 805  VGFQGKTGPPGPPGVVGPQ-----GAAGETGPMGERGHPGPPGP---------------- 843
             G  G  GPPGPPG +GP      G  GE G  G+ G PGP GP                
Sbjct: 198  AGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGK 257

Query: 844  ------PGEQGLP-----------GTAGKEGTKGDPGPPGAPGKDGP---AGLRGFPGER 883
                  PG +G P           GT G++G KG+ G PG PG  GP    G++G PG++
Sbjct: 258  KGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQ 317

Query: 884  GLPGTAGGPGL-----------------------------KGNEGPSGPPGPAGSPGERG 914
            G  GT G PGL                              GN G  G PG  G  G+ G
Sbjct: 318  GKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEG 377

Query: 915  AAGSGGPIGPPGRP---------GPQGPPGAAGEKGVPGEK--GPIGPTGRDGVQGPVGL 963
              G  GP G PG P         GPQG PG  G++G PG    G  G  GRDG+ GP G 
Sbjct: 378  IQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGP 437

Query: 964  PGPAGP--------------PGVAGEDGDKGEVGDPGQKGTKG---------NKGEHGPP 1000
            PGP  P              PG+ GE G KG +G  G KG  G         N G  G P
Sbjct: 438  PGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEP 497

Query: 1001 GPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIG------LQGLP 1054
            GPPGP G +G PG  GA G+ G+ G QG  GA G  G  G +GP G  G      +QG+P
Sbjct: 498  GPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMP 557

Query: 1055 GPSGEKGETGDVGPMGPPGPPGPRGPAGPNG--ADGPQGPPGGVGNLGPPGEKGEPGESG 1112
            G  G+ G  G  G +G PG  G  G  G  G   DG QG PG  G  G PGEKG PG  G
Sbjct: 558  GDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPG 617

Query: 1113 SPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT------GDDGPKGNPGPVGFPG 1166
             PG  G PG+ GPRG  G+KG+ G PG+ G PG KG T      G  GP G PG  GFPG
Sbjct: 618  LPG-NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPG 676

Query: 1167 DPGPPGEGGPRGQDGAKGDRGEDGEPG------QPGSPGPTGENGPPGPLGKRGPAGSP- 1219
              G  G  G  GQ G+ G +GE G PG       PG PGP GE G PG  G  G  G P 
Sbjct: 677  PKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPG 736

Query: 1220 --GSEGRQGGKGAKGD--------PGAIGAPGKTGPVGPAGPAGKP------------GP 1257
              GS G  G KGA GD        PG  G  G TG  G  G +G P            GP
Sbjct: 737  MIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGP 796

Query: 1258 DGLRGLPGSVGQQGRPGATGQAGP---------PGPVGPPGLPGLRGDAGAKGEKGHPGL 1308
             G RG PG+ GQ G+PG  G +GP         PG  G PG+ G  G  G +G+KG PG 
Sbjct: 797  KGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGS 856

Query: 1309 IGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIG----------PG--GPPGL 1356
            I   G PG +G  G+ GL G +GSPG  G  G+P  SGP G          PG  G PG+
Sbjct: 857  IVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGI 916

Query: 1357 PGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQ 1416
            PG  G KG  G+TG  GP G  G  G  G  G PG V  P P       RR +    L  
Sbjct: 917  PGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSP-------RRPMSNLWLKG 969

Query: 1417 EDEAIPTGGAPGSPG 1431
            +  +  + G+ G PG
Sbjct: 970  DKGSQGSAGSNGFPG 984



 Score =  105 bits (262), Expect = 4e-22
 Identities = 73/191 (38%), Positives = 86/191 (45%), Gaps = 11/191 (5%)

Query: 1243 TGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1302
            T  +  AG      P G +   GS       GA G+ GP G  GP G  G  G  G  G 
Sbjct: 16   TEELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGL 75

Query: 1303 KGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGP 1362
            KG  G  GL+GP G +G+KG  G+      PG  G  GIPG  G  GP GPPGL    G 
Sbjct: 76   KGERGFPGLLGPYGPKGDKGPMGV------PGFLGINGIPGHPGQPGPRGPPGLD---GC 126

Query: 1363 KGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP 1422
             G +GA G  GP G  G+ GPPG PG  G   +  P+  P   +       L   D    
Sbjct: 127  NGTQGAVGFPGPDGYPGLLGPPGLPGQKGS--KGDPVLAPGSFKGMKGDPGLPGLDGITG 184

Query: 1423 TGGAPGSPGGL 1433
              GAPG PG +
Sbjct: 185  PQGAPGFPGAV 195


>gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo
            sapiens]
          Length = 1690

 Score =  805 bits (2078), Expect = 0.0
 Identities = 548/1395 (39%), Positives = 640/1395 (45%), Gaps = 270/1395 (19%)

Query: 270  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPG---- 325
            G  GLKGE+G P +L P     GP G +GP G+ G  GI G PG  G PG RGPPG    
Sbjct: 70   GLSGLKGERGFPGLLGP----YGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGC 125

Query: 326  -----RAGLPGSDGAPG---PPGTS---------LMLPFRFGSGGGDKG-PVVAAQEAQA 367
                   G PG DG PG   PPG           ++ P  F    GD G P +       
Sbjct: 126  NGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQ 185

Query: 368  QAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGL-----KGESGDLGPQGPRGPQGLTG 422
             A      +   GPPG  G  G PGPLG  G+ GL     KG  GD+G  GP GP   TG
Sbjct: 186  GAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTG 245

Query: 423  -------PPGKAGRRGRAGADGARGMPGDPGV--------KGDRGFDGLPGLPGEKGHRG 467
                   P GK G +G  G  G  G+ G PG         KG++G  G+PGLPG +G  G
Sbjct: 246  ELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMG 305

Query: 468  DTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPK--------------GPPGI 513
              G QG PG  G+ G  G  G  G +G+ G+ G  GL GP               G PG+
Sbjct: 306  SEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGV 365

Query: 514  PGPPGVRGMDGPQGPKG---------------SLGPQGEPGPPGQQGTPGT--------- 549
            PG PG++G +G QG +G               +LGPQG PG  G QG PG          
Sbjct: 366  PGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLP 425

Query: 550  --QGLPGPQGAIGP--------------------HGEKGPQGKPGLPGMPGSDG------ 581
               GLPGP G  GP                     GE+GP+G  GL G+ G  G      
Sbjct: 426  GRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDG 485

Query: 582  ------PPGHPGKEGP---------PGTKGNQGPSGPQGPLGYPG---------PRGVKG 617
                  PPG PG  GP          G +G++G  G QGP G PG         P+G KG
Sbjct: 486  GVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKG 545

Query: 618  V---------------DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDG 662
                             G +G +G  GE G+DG PG  G  G+ GD G+ G PG +G  G
Sbjct: 546  EPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQ-GFPGEKGLPG 604

Query: 663  PEGPKGRTGPTGDPG--------PPGLMGEKGKLGVPGLPGYPGRQG---------PKGS 705
              G KG  GP G PG        P GL G+KGK G+PG  G PG +G           G 
Sbjct: 605  LPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGP 664

Query: 706  LGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRG------------PRGATGKSGA 753
             GFPG PG  G KG+RGL G  G  G  G  G  G  G            PRG  G  G 
Sbjct: 665  SGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGF 724

Query: 754  KGTSGGDGPHGPPGERGLPGPQGPNG--FPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKT 811
             G  G DG  G  G  GLPG +G  G  F    G PG  G  GL GH G  G+ G  G  
Sbjct: 725  PGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLK 784

Query: 812  GPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKD 871
            G  G PG++GP+G  G  G  G+ G PG PG  G  G+ G +G  G  G PG  G PGK 
Sbjct: 785  GVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKK 844

Query: 872  GPAGLRGFPG---ERGLPGTAG---GPGLKGNEGPSGPPGPAGSP---GERGAAGSGGPI 922
            G  G +G PG   ++GLPG  G    PGL G +G  G PG AG P   G +G  GS G +
Sbjct: 845  GTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFV 904

Query: 923  GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQG---------PVGLPGPAGPPG-- 971
            G PG PG  G PG  G KG+PG  G +GP+GR G  G         PVG+P P  P    
Sbjct: 905  GFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNL 964

Query: 972  -VAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPG----AAGADGEPGARGP 1026
             + G+ G +G  G  G  G +G+KGE G PGPPG  G  G PG     +G  G PG  G 
Sbjct: 965  WLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGI 1024

Query: 1027 QGHFGAKGDEGTRGFNGPPGPIGLQG------LPGPSGEKGETGDVGP-MGPPGPPGPRG 1079
            +G  G KG  G  GF G PG  G QG      LPG SG  G  GD G  +   G PGP+G
Sbjct: 1025 RGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKG 1084

Query: 1080 PAGPNGADGPQGPPGGVGNLGPPGEKGEPGE---SGSPGIQGEPGVKGPRGERGEKGESG 1136
              G +G  G +G  G +GN+G PG KGE G+   SG  G+ G PG  G  G RGE G  G
Sbjct: 1085 QPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPG 1144

Query: 1137 QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAK-----------GD 1185
              G  G  GP G  G  GPKG PG  G  G  G PG  G  G  G             G 
Sbjct: 1145 SSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGP 1204

Query: 1186 RGEDGEPG----QPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPG 1241
            +GE G PG     PG PG  G+ G  G  G +GPAG PG+ G        G PG  G PG
Sbjct: 1205 KGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPG 1264

Query: 1242 KTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKG 1301
              G  G  GPAG PGP G     G  G  G PG  G  GP G  G PG  GL G+ G KG
Sbjct: 1265 LDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKG 1324

Query: 1302 EKGHPGLIGL---IGPPGEQGEKGDRGLPGPQGSPGQKGE-------------------- 1338
             +G PG +G    +GPPG+ G  G +G  GP+GS G +G+                    
Sbjct: 1325 MRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLP 1384

Query: 1339 --------MGIPGASGPI---GPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHP 1387
                     G PGA GP+   G  G PG+PG  GP G  G  G  G  G  G+QGPPG  
Sbjct: 1385 GIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFE 1444

Query: 1388 GPPGEVIQPLPIQMP 1402
            G PG   Q  P  MP
Sbjct: 1445 GAPG---QQGPFGMP 1456



 Score =  800 bits (2066), Expect = 0.0
 Identities = 542/1356 (39%), Positives = 635/1356 (46%), Gaps = 242/1356 (17%)

Query: 269  HGPRGLKGEKGEPAVLE----PGMLVEGPPGPEGPAGLIGPPGIQGN---PGPVGDPGER 321
            +GP+G KG  G P  L     PG    G PGP GP GL G  G QG    PGP G PG  
Sbjct: 87   YGPKGDKGPMGVPGFLGINGIPGH--PGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLL 144

Query: 322  GPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKG-PVVAAQEAQAQAILQQARLALRG 380
            GPP   GLPG  G+ G P   ++ P  F    GD G P +        A      +   G
Sbjct: 145  GPP---GLPGQKGSKGDP---VLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAG 198

Query: 381  PPGPMGYTGRPGPLGQPGSPGL-----KGESGDLGPQGPRGPQGLTG-------PPGKAG 428
            PPG  G  G PGPLG  G+ GL     KG  GD+G  GP GP   TG       P GK G
Sbjct: 199  PPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKG 258

Query: 429  RRGRAGADGARGMPGDPGV--------KGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGE 480
             +G  G  G  G+ G PG         KG++G  G+PGLPG +G  G  G QG PG  G+
Sbjct: 259  SKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGK 318

Query: 481  DGERGDDGEIGPRGLPGESGPRGLLGP--------------KGPPGIPGPPGVRGMDGPQ 526
             G  G  G  G +G+ G+ G  GL GP               G PG+PG PG++G +G Q
Sbjct: 319  KGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQ 378

Query: 527  GPK---------------GSLGPQGEPGPPGQQGT-----------PGTQGLPGPQGAIG 560
            G +               G+LGPQG PG  G QG            PG  GLPGP G  G
Sbjct: 379  GLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPG 438

Query: 561  P--------------------HGEKGPQGKPGLPGMPG------------SDGPPGHPGK 588
            P                     GE+GP+G  GL G+ G            + GPPG PG 
Sbjct: 439  PPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGP 498

Query: 589  EGP---------PGTKGNQGPSGPQGPLGYP---------GPRGVKGV------------ 618
             GP          G +G++G  G QGP G P         GP+G KG             
Sbjct: 499  PGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGD 558

Query: 619  ---DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGP--- 672
                G +G +G  GE G+DG PG  G  G+ GD G+ G PG +G  G  G KG  GP   
Sbjct: 559  RGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQ-GFPGEKGLPGLPGEKGHPGPPGL 617

Query: 673  -----TGDPGPPGLMGEKGKLGVPGLPGYPGRQ---------GPKGSLGFPGFPGASGEK 718
                  G PGP GL G+KGK G+PG  G PG +         G  G  GFPG PG  G K
Sbjct: 618  PGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPK 677

Query: 719  GARGLSGKSGPRGERGPTGPRGQ------------RGPRGATGKSGAKGTSGGDGPHGPP 766
            G+RGL G  G  G  G  G  G              GPRG  G  G  G  G DG  G  
Sbjct: 678  GSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMI 737

Query: 767  GERGLPGPQGPNG--FPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQG 824
            G  GLPG +G  G  F    G PG  G  GL GH G  G+ G  G  G  G PG++GP+G
Sbjct: 738  GSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKG 797

Query: 825  AAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG--- 881
              G  G  G+ G PG PG  G  G+ G +G  G  G PG  G PGK G  G +G PG   
Sbjct: 798  ERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIV 857

Query: 882  ERGLP---GTAGGPGLKGNEGPSGPPGPAGSP---GERGAAGSGGPIGPPGRPGPQGPPG 935
            ++GLP   G  G PGL G +G  G PG AG P   G +G  GS G +G PG PG  G PG
Sbjct: 858  KKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPG 917

Query: 936  AAGEKGVPGEKGPIGPTGRDGV---------QGPVGLPGPAGPPG---VAGEDGDKGEVG 983
              G KG+PG  G +GP+GR G           GPVG+P P  P     + G+ G +G  G
Sbjct: 918  TRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAG 977

Query: 984  DPGQKGTKGNKGEHGPPGPPGPIGPVGQP----GAAGADGEPGARGPQGHFGAKGDEGTR 1039
              G  G +G+KGE G PGPPG  G  G P    G +G  G PG  G +G  G KG  G  
Sbjct: 978  SNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGIT 1037

Query: 1040 GFNGPPGPIGLQ------GLPGPSGEKGETGDVG-PMGPPGPPGPRGPAGPNGADGPQGP 1092
            GF G PG  G Q      GLPG SG  G  GD G  +   G PGP+G  G +G  G +G 
Sbjct: 1038 GFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGR 1097

Query: 1093 PGGVGNLGPPGEKGEPGE---SGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGP 1149
             G +GN+G PG KGE G+   SG  G+ G PG  G  G RGE G  G  G  G  GP G 
Sbjct: 1098 DGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGS 1157

Query: 1150 TGDDGPK------------GNPGPVGFPGDPGP--PGEGGPRGQDGAKGDRGEDG-EPGQ 1194
             G  GPK            G PG  G  G PGP   G  GP G  G KG++G  G   G 
Sbjct: 1158 PGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGA 1217

Query: 1195 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1254
            PG PG  G+ G  G  G +GPAG PG+ G        G PG  G PG  G  G  GPAG 
Sbjct: 1218 PGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGP 1277

Query: 1255 PGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL--- 1311
            PGP G     G  G  G PG  G  GP G  G PG  GL G+ G KG +G PG +G    
Sbjct: 1278 PGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGK 1337

Query: 1312 IGPPGE------QGEKGDRGLPGPQGSPGQ----------KGEMGIPGASGPIGPGGPPG 1355
            +GPPG+      +G+ G RG  G QG PGQ           G +G+PG  G  G  G PG
Sbjct: 1338 VGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPG 1397

Query: 1356 LPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1391
              GP G +G+KG  G  G  G  G+ GPPG  G PG
Sbjct: 1398 AQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPG 1433



 Score =  792 bits (2045), Expect = 0.0
 Identities = 545/1379 (39%), Positives = 637/1379 (46%), Gaps = 250/1379 (18%)

Query: 275  KGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPG------PVGDPGERGPPGRAG 328
            KG +G P  +     ++GP GP+G  G  G  G++G  G      P G  G++GP G  G
Sbjct: 45   KGARGRPGPIG----IQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPG 100

Query: 329  LPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYT 388
              G +G PG PG             G +GP         Q  +        G PGP GY 
Sbjct: 101  FLGINGIPGHPGQP-----------GPRGPPGLDGCNGTQGAV--------GFPGPDGY- 140

Query: 389  GRPGPLGQPGSPGLKGESGD-----------LGPQGPRGPQGLTGP---PGKAGRRGRAG 434
              PG LG PG PG KG  GD            G  G  G  G+TGP   PG  G  G AG
Sbjct: 141  --PGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAG 198

Query: 435  ADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGE----------R 484
              G +G PG PG  G  G  GL G  GEKG +GD G  G  GPP   GE          +
Sbjct: 199  PPGLQGPPGPPGPLGPDGNMGL-GFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKK 257

Query: 485  GDDGEIGPRGLPGESGPRGL--LGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPG 542
            G  GE GP+G PG SGP G   LG  G  G  G  G+ G+ GP+GP GS G Q   GPPG
Sbjct: 258  GSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQ---GPPG 314

Query: 543  QQGTPGTQGLPGPQGAIGPHGEKGPQGKPG-----------LPGMPGSDGPPGHPGKEGP 591
            QQG  GT G PG  G  G  G+KG  G PG           + G PG  G PG PG +G 
Sbjct: 315  QQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGD 374

Query: 592  PGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG------------------- 632
             G +G +GPSG  G     G  G  G  G  GLKG +G  G                   
Sbjct: 375  EGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPP 434

Query: 633  ------------------EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTG 674
                              E GFPG +G+ G KG+ G  G+ G  G    +G    TGP G
Sbjct: 435  GPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPG 494

Query: 675  DPGPP---GLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARG---LSGKSG 728
            +PGPP   GL+G  G  G  G  G  G QGP G+ G  G  G SG KG +G   LS   G
Sbjct: 495  EPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQG 554

Query: 729  PRGERGPTGPRGQRGPRGATGKSGAKGTSG-----GDGPHGPPGERGLPGPQGPNGFPGP 783
              G+RG +G +G RG  G  GK G  G  G     GDG  G PGE+GLPG  G  G PGP
Sbjct: 555  MPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGP 614

Query: 784  KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAA------GETGPMGERGH 837
             G PG    +GLPG PG RG  G +GK G PG  G+ G +G        G  GP G  G 
Sbjct: 615  PGLPG----NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGT 670

Query: 838  PGPPGPPGEQGLPGTAGK---EGTKGDPGPPGA---------PGKDGPAGLRGF---PGE 882
            PG PGP G +GLPGT G+    G+KG+PG PG          PG  G  GL GF   PG+
Sbjct: 671  PGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGK 730

Query: 883  RGLPGTAGGPGLKGNEGPSGP-----------------------PGPAGSPGERGAAGSG 919
             GLPG  G PGL G++G +G                         G +G PG +G  G  
Sbjct: 731  DGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKP 790

Query: 920  GPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDK 979
            G +GP G  G  G PG  G+ G PG  GP G  G+ G+ G  G PG +G PG  G  G K
Sbjct: 791  GLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKK 850

Query: 980  GEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1039
            G  G   +KG  G KG  G PG  G  G  G PG AG     G +G +G  G  G  G  
Sbjct: 851  GPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIP 910

Query: 1040 GFNGPPGPIGLQGLPGPS------------GEKGETGDVGPMGPPGP------------P 1075
            G  G PG  GL+G+PG +            GEKG+ G+ GP+G P P             
Sbjct: 911  GLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDK 970

Query: 1076 GPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG----ESGSPGIQGEPGVKGPRGERGE 1131
            G +G AG NG  GP+G  G  G  GPPG  G PG      G  G  G PG  G RG  G 
Sbjct: 971  GSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGL 1030

Query: 1132 KGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGE-------GGPRGQDGAKG 1184
            KG SG  G PG PG  G  G  G  G PG  G PG  G  G+        GP+GQ G  G
Sbjct: 1031 KGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESG 1090

Query: 1185 DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1244
             +G  G  G  G+ G  G  G  G +G  G  G PG+ G  G  G +G+PG  G+ G  G
Sbjct: 1091 FKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQG 1150

Query: 1245 PVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKG 1304
             +GP G  G  GP G  G PG  G  G PG  G  G PGP    G+PG  G  G KGEKG
Sbjct: 1151 AIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGP-SITGVPGPAGLPGPKGEKG 1209

Query: 1305 HPGL-IGLIGPPGEQGEKGDRGLPGPQ------------------------GSPGQKGEM 1339
            +PG+ IG  G PG +G+KGDRG PG Q                        G PG  GE 
Sbjct: 1210 YPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGER 1269

Query: 1340 GIPGASGPIGPGGP------------PGLPGPAGPKGAKGATGPGGPKGE---KGVQGPP 1384
            G PG +GP GP GP            PG+PGP GPKG +G  G  G  GE   KG++G P
Sbjct: 1270 GRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEP 1329

Query: 1385 GHPGPPGEVIQPLPIQMP-KKTRRSVDGSRLMQEDEA-IPTGGA---PGSPGGLEEIFG 1438
            G  G PG+V  P     P  K +    GS  +Q D    PT  A   P  P GL  I G
Sbjct: 1330 GFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDG 1388



 Score =  730 bits (1884), Expect = 0.0
 Identities = 475/1124 (42%), Positives = 548/1124 (48%), Gaps = 126/1124 (11%)

Query: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 322
            P  +   G +GL+G  G P +      + G PG  GP G  G  G QGNPG     G  G
Sbjct: 369  PGLKGDEGIQGLRGPSGVPGL----PALSGVPGALGPQGFPGLKGDQGNPGRT-TIGAAG 423

Query: 323  PPGRAGLPGSDGAPGPPG----TSLMLPFRFGSGG--GDKGPV----VAAQEAQAQAILQ 372
             PGR GLPG  G PGPP     T  +     G  G  G++GP     +   +  +     
Sbjct: 424  LPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCAC 483

Query: 373  QARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGR 432
               +   GPPG  G  G  G +G PG  G +G+ G  G QGP G  GL GP G +G +G+
Sbjct: 484  DGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGK 543

Query: 433  AGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGP 492
             G      + G PG +GD G  G  G+ GE G  G  G  GLPG PG+ G+         
Sbjct: 544  KGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQ--------- 594

Query: 493  RGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGL 552
             G PGE G  GL G KG PG PG PG  G+ G  GP+G  G +G+ G PGQQG PG++G+
Sbjct: 595  -GFPGEKGLPGLPGEKGHPGPPGLPG-NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGI 652

Query: 553  PGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSG----PQGPLG 608
              P    G +G  G  G PG PG  GS G PG PG+ G  G+KG  G  G    P+ P G
Sbjct: 653  TLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELP-G 711

Query: 609  YPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGD--RGEVGVPGSRGEDGPEGP 666
            +PGPRG KG+ G  GL G  G  G  G PG  G  G  GD    E G PG +G  G  G 
Sbjct: 712  FPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGH 771

Query: 667  KGRTGPTGDPG------PPGLMGEKGKLGVPGLPGY------PGRQGPKGSLGFPGFPGA 714
            KG  G +G PG       PGL+G KG+ G PG PG       PG  GP G  G  G PGA
Sbjct: 772  KGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGA 831

Query: 715  SGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGP 774
             G  G  G  GK G RG++GP G   ++G  G  G  G  G  G  G  G PG  GLP  
Sbjct: 832  PGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPAL 891

Query: 775  QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 834
             GP G  G  G  G PG  GLPG PG RG  G  G TG       +GP G AG  G  G+
Sbjct: 892  SGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGK------MGPSGRAGTPGEKGD 945

Query: 835  RGHPGPPGPP---------------------GEQGLPGTAGKEGTKGDPGPPGAPGKDGP 873
            RG+PGP G P                     G  G PG  G +G  G PGPPG PG  G 
Sbjct: 946  RGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGL 1005

Query: 874  AGL----RGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPG 929
             G+     G PG  G  G  G PGLKG+ G +G PG  G  G +G  GS G  G  G PG
Sbjct: 1006 PGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPG 1065

Query: 930  PQGP-------PGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 982
             +G         G+ G KG PGE G  G  GRDG+ G +G PG  G  G  G  GD G  
Sbjct: 1066 LKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLP 1125

Query: 983  GDPGQKGTKGNKGEHGPPGPPG---PIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1039
            G PG  G  G +GE G PG  G    IGP+G PG  G  G PG  G  G  G  G +GT 
Sbjct: 1126 GAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTH 1185

Query: 1040 GFNGPP--GPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGP---PG 1094
            G  GP   G  G  GLPGP GEKG  G +G +G PG PG RG  G  G  G QGP   PG
Sbjct: 1186 GTPGPSITGVPGPAGLPGPKGEKGYPG-IG-IGAPGKPGLRGQKGDRGFPGLQGPAGLPG 1243

Query: 1095 GVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERG------EKGESGQPGEPGPPGPKG 1148
              G   P    G+PG+ G PG+ GE G  GP G  G       +G++G PG PG PGPKG
Sbjct: 1244 APGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKG 1303

Query: 1149 PTGDDG---------------PKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1193
            P GD G                +G PG +G PG  GPPG+ G  G  G  G RG  G  G
Sbjct: 1304 PKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQG 1363

Query: 1194 QPGSPGPTGE--NGPPGPLGKRGPAGSPG---SEGRQGGKGAKGDPGAIGAPGKTGPVGP 1248
             PG   PT E    PPGPLG  G  G PG     G QG  G +G  G  G PGK      
Sbjct: 1364 DPGQT-PTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKD----- 1417

Query: 1249 AGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG 1292
             GP+G PGP G  G PG  G QG PG  G  G  GP G PG+PG
Sbjct: 1418 -GPSGLPGPPGALGDPGLPGLQGPPGFEGAPGQQGPFGMPGMPG 1460



 Score =  690 bits (1780), Expect = 0.0
 Identities = 476/1268 (37%), Positives = 553/1268 (43%), Gaps = 304/1268 (23%)

Query: 461  GEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVR 520
            GEK +    G Q   G      E+G  G  GP G+ G +GP+G  G  G  G+ G  G  
Sbjct: 22   GEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFP 81

Query: 521  GMDGPQGPKGSLGPQ------------GEPGPPGQQGTPGTQGLPGPQGAIG-------- 560
            G+ GP GPKG  GP             G PG PG +G PG  G  G QGA+G        
Sbjct: 82   GLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYP 141

Query: 561  ---------------------PHGEKGPQGKPGLPGMPGSDGP---PGHPGKEGPPGTKG 596
                                 P   KG +G PGLPG+ G  GP   PG PG  GP G  G
Sbjct: 142  GLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPG 201

Query: 597  NQGPSGPQGP--------LGYPGPRGVKGVDGI-------------------RGLKGHKG 629
             QGP GP GP        LG+ G +GVKG  G+                   +G KG KG
Sbjct: 202  LQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKG 261

Query: 630  EKGEDGFPGFKGDIGVK--GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 687
            E G  GFPG  G  G    G  GE G  G +G  G  GP+G  G  G  GPPG  G+KG 
Sbjct: 262  EPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGT 321

Query: 688  LGVPGLPGYPGRQGPKGSLGF-----------------------PGFPGASGEKGARGLS 724
            LG PGL G+ G +G KG +G                        PG PG  G++G +GL 
Sbjct: 322  LGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLR 381

Query: 725  GK---------SGPRGERGPTGPRGQRGPRGATGKS--GAKGTSGGDGPHGPPGERGLPG 773
            G          SG  G  GP G  G +G +G  G++  GA G  G DG  GPPG  G P 
Sbjct: 382  GPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPS 441

Query: 774  P--------------------QGPNGF------------------------PGPKGPPGP 789
            P                    QGP G                         PG  GPPGP
Sbjct: 442  PEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGP 501

Query: 790  PGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE------RGHPGPPGP 843
             G  GLPG  G RG+ G  G  GP G PG+VGP G +G  G  GE      +G PG  G 
Sbjct: 502  WGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGD 561

Query: 844  PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGT------AGGPGLKGN 897
             G QG  G  G+ G  G PG PG PG  G  G +GFPGE+GLPG        G PGL GN
Sbjct: 562  SGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGG-QGFPGEKGLPGLPGEKGHPGPPGLPGN 620

Query: 898  EGPSGPPGPAGSPGERG---------------------AAGSGGPIGPPGRPGPQGPPGA 936
             G  G PGP G PG++G                       GS GP G PG PG  GP G+
Sbjct: 621  -GLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGS 679

Query: 937  AGEKGVPGEKGPIGPTGRDGVQGPV------GLPGPAGP------PGVAGEDGDKGEVGD 984
             G  G PG+ G  G  G  G  G V      G PGP G       PG+ G+DG  G +G 
Sbjct: 680  RGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGS 739

Query: 985  PGQKGTKGNKG-----EHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1039
            PG  G+KG  G     E+G PG  G  G  G  G  G  G PG +G  G  G  G +G R
Sbjct: 740  PGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGER 799

Query: 1040 GFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNL 1099
            G  G PG +G  G PG SG  G  G  G  G PG PG  G  G  G  G +GPPG +   
Sbjct: 800  GSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKK 859

Query: 1100 GPPGEKGEP---------GESGSPGIQGEPGVKGPRGERGEKGESGQPGEP--------- 1141
            G PG KG P         G  GSPG+ G P + GP+GE+G  G  G PG P         
Sbjct: 860  GLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTR 919

Query: 1142 ------------GPPGPKGPTGDDGPKGNPGPVGFP------------GDPGPPGEGGPR 1177
                        GP G  G  G+ G +GNPGPVG P            GD G  G  G  
Sbjct: 920  GLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSN 979

Query: 1178 GQDGAKGDRGEDGEPGQPGSPGP----------TGENGPPGPLGKRGP------------ 1215
            G  G +GD+GE G PG PG PG           +G+ GPPG +G RG             
Sbjct: 980  GFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGF 1039

Query: 1216 AGSPGSEGRQGGKGAKGDPGAIGAPGKTGP-------VGPAGPAGKPGPDGLR------- 1261
             G PG  G QG +G+ G PGA G PG  G         G  GP G+PG  G +       
Sbjct: 1040 PGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDG 1099

Query: 1262 -----GLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG 1316
                 G PG+ G+ G+ G +G  G PG  G PG+ G+RG+ G  G  GH G IG +G PG
Sbjct: 1100 LIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPG 1159

Query: 1317 EQGEKGDRGLPGPQGSPGQKGEMGIPGASGP--IGPGGPPGLPGPAGPK-------GAKG 1367
              G KG  G PG  G  G  G  G  G  GP   G  GP GLPGP G K       GA G
Sbjct: 1160 LIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAPG 1219

Query: 1368 ATGPGGPKGEK---GVQGPPGHPGPPGEVIQPLPIQMP-KKTRRSVDGSRLMQEDEAIPT 1423
              G  G KG++   G+QGP G PG PG  +  L    P    R  +DG R          
Sbjct: 1220 KPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGER-----GRPGP 1274

Query: 1424 GGAPGSPG 1431
             G PG PG
Sbjct: 1275 AGPPGPPG 1282



 Score =  562 bits (1448), Expect = e-159
 Identities = 369/899 (41%), Positives = 437/899 (48%), Gaps = 130/899 (14%)

Query: 270  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPA------GLIGPPGIQGNPGPVGDPGERGP 323
            GPRGL G+KG+  +  PG   +G PG +G        G  GP G  G PG  G  G RG 
Sbjct: 627  GPRGLPGDKGKDGL--PGQ--QGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGL 682

Query: 324  PGRAGLPGSDGAPGPPGTS--LMLPFRFGSGG--GDKG----PVVAAQEAQAQAI----- 370
            PG  G PGS G+ G PG+   + LP   G  G  G+KG    P +  ++     I     
Sbjct: 683  PGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGL 742

Query: 371  ---------LQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLT 421
                     +  A     G  G  G TG  G LG  G PGLKG  G  G  GP+G +G  
Sbjct: 743  PGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSP 802

Query: 422  GPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGA---------- 471
            G PG+ G+ G  G+ G  G+ G  G+ G  GF G+ G PG+KG RG  G           
Sbjct: 803  GTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLP 862

Query: 472  --QGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPK 529
              +GLPG PG  G +G  G  G  GLP  SGP+G  G  G  G PG PG+ G+ G +G K
Sbjct: 863  GLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLK 922

Query: 530  GSLGPQGEPGPPGQQGTP---GTQGLPGPQGAIGPH---------GEKGPQGKPGLPGMP 577
            G  G  G+ GP G+ GTP   G +G PGP G   P          G+KG QG  G  G P
Sbjct: 923  GIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFP 982

Query: 578  GSDGPPGHPGKEGPPGTKGNQG-PSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF 636
            G  G  G  G+ GPPG  G  G P   +G  G PGP G     GIRGL G KG  G  GF
Sbjct: 983  GPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFM---GIRGLPGLKGSSGITGF 1039

Query: 637  PGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRT-------GPTGDPGPPGLMGEKGKLG 689
            PG  G+ G +G RG  G+PG+ G  G +G  G+T       GP G PG  G  G KG+ G
Sbjct: 1040 PGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDG 1099

Query: 690  VPGLPGYPGRQGPKGSLGF---------PGFPGASGEKGARGLSGKSGPRGERGPTGPRG 740
            + G  G+PG +G  G +G          PGFPG +G +G  GL G SG +G  GP G  G
Sbjct: 1100 LIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPG 1159

Query: 741  QRGPR---------GATGKSGAKGTSGGDGPH--GPPGERGLPGPQGPNGFPGPKGPPGP 789
              GP+         G  G  G KGT G  GP   G PG  GLPGP+G  G+PG     G 
Sbjct: 1160 LIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGI--GIGA 1217

Query: 790  PGKDGLPGHPGQRGEVGFQGKTGPPGPPG------VVGPQGAAGETGPMGERGHPGPPGP 843
            PGK GL G  G RG  G QG  G PG PG      + G  G  G  G  GERG PGP GP
Sbjct: 1218 PGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGP 1277

Query: 844  PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 903
            PG    PG +  +G  GDPG PG PG  GP G +G PG  GLPG  G  G++G  G  G 
Sbjct: 1278 PGP---PGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGT 1334

Query: 904  PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ---GP 960
            PG  G PG+ G  G  G  GP G  G QG PG               PT  + VQ   GP
Sbjct: 1335 PGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQT-------------PTA-EAVQVPPGP 1380

Query: 961  VGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGE 1020
            +GLPG  G PG+ G+ G +G VG  G KG  G  G+ GP G PGP      PGA G  G 
Sbjct: 1381 LGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGP------PGALGDPGL 1434

Query: 1021 PGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG 1079
            PG +GP G  GA G +         GP G+ G+PG S   G T          PP P G
Sbjct: 1435 PGLQGPPGFEGAPGQQ---------GPFGMPGMPGQSMRVGYTLVKHSQSEQVPPCPIG 1484



 Score =  544 bits (1402), Expect = e-154
 Identities = 382/975 (39%), Positives = 438/975 (44%), Gaps = 202/975 (20%)

Query: 651  EVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGV------PGLPGYPGRQGPKG 704
            E+   G +    P G +  +G        G  G  G +G+       G  G  G  G KG
Sbjct: 17   ELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKG 76

Query: 705  SLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHG 764
              GFPG  G  G KG +G  G  G  G  G  G  GQ GPRG  G  G  GT G  G  G
Sbjct: 77   ERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPG 136

Query: 765  PPGERGLPGPQG--------------PNGFPGPKGPPGPPGKDGL------PGHPGQRGE 804
            P G  GL GP G              P  F G KG PG PG DG+      PG PG  G 
Sbjct: 137  PDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGP 196

Query: 805  VGFQGKTGPPGPPGVVGPQ-----GAAGETGPMGERGHPGPPGP---------------- 843
             G  G  GPPGPPG +GP      G  GE G  G+ G PGP GP                
Sbjct: 197  AGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGK 256

Query: 844  ------PGEQGLP-----------GTAGKEGTKGDPGPPGAPGKDGP---AGLRGFPGER 883
                  PG +G P           GT G++G KG+ G PG PG  GP    G++G PG++
Sbjct: 257  KGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQ 316

Query: 884  GLPGTAGGPGL-----------------------------KGNEGPSGPPGPAGSPGERG 914
            G  GT G PGL                              GN G  G PG  G  G+ G
Sbjct: 317  GKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEG 376

Query: 915  AAGSGGPIGPPGRP---------GPQGPPGAAGEKGVPGEK--GPIGPTGRDGVQGPVGL 963
              G  GP G PG P         GPQG PG  G++G PG    G  G  GRDG+ GP G 
Sbjct: 377  IQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGP 436

Query: 964  PGPAGP--------------PGVAGEDGDKGEVGDPGQKGTKG---------NKGEHGPP 1000
            PGP  P              PG+ GE G KG +G  G KG  G         N G  G P
Sbjct: 437  PGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEP 496

Query: 1001 GPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIG------LQGLP 1054
            GPPGP G +G PG  GA G+ G+ G QG  GA G  G  G +GP G  G      +QG+P
Sbjct: 497  GPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMP 556

Query: 1055 GPSGEKGETGDVGPMGPPGPPGPRGPAGPNG--ADGPQGPPGGVGNLGPPGEKGEPGESG 1112
            G  G+ G  G  G +G PG  G  G  G  G   DG QG PG  G  G PGEKG PG  G
Sbjct: 557  GDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPG 616

Query: 1113 SPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT------GDDGPKGNPGPVGFPG 1166
             PG  G PG+ GPRG  G+KG+ G PG+ G PG KG T      G  GP G PG  GFPG
Sbjct: 617  LPG-NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPG 675

Query: 1167 DPGPPGEGGPRGQDGAKGDRGEDGEPG------QPGSPGPTGENGPPGPLGKRGPAGSP- 1219
              G  G  G  GQ G+ G +GE G PG       PG PGP GE G PG  G  G  G P 
Sbjct: 676  PKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPG 735

Query: 1220 --GSEGRQGGKGAKGD--------PGAIGAPGKTGPVGPAGPAGKP------------GP 1257
              GS G  G KGA GD        PG  G  G TG  G  G +G P            GP
Sbjct: 736  MIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGP 795

Query: 1258 DGLRGLPGSVGQQGRPGATGQAGP---------PGPVGPPGLPGLRGDAGAKGEKGHPGL 1308
             G RG PG+ GQ G+PG  G +GP         PG  G PG+ G  G  G +G+KG PG 
Sbjct: 796  KGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGS 855

Query: 1309 IGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIG----------PG--GPPGL 1356
            I   G PG +G  G+ GL G +GSPG  G  G+P  SGP G          PG  G PG+
Sbjct: 856  IVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGI 915

Query: 1357 PGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQ 1416
            PG  G KG  G+TG  GP G  G  G  G  G PG V  P P       RR +    L  
Sbjct: 916  PGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSP-------RRPMSNLWLKG 968

Query: 1417 EDEAIPTGGAPGSPG 1431
            +  +  + G+ G PG
Sbjct: 969  DKGSQGSAGSNGFPG 983



 Score =  105 bits (262), Expect = 4e-22
 Identities = 73/191 (38%), Positives = 86/191 (45%), Gaps = 11/191 (5%)

Query: 1243 TGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1302
            T  +  AG      P G +   GS       GA G+ GP G  GP G  G  G  G  G 
Sbjct: 15   TEELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGL 74

Query: 1303 KGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGP 1362
            KG  G  GL+GP G +G+KG  G+      PG  G  GIPG  G  GP GPPGL    G 
Sbjct: 75   KGERGFPGLLGPYGPKGDKGPMGV------PGFLGINGIPGHPGQPGPRGPPGLD---GC 125

Query: 1363 KGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP 1422
             G +GA G  GP G  G+ GPPG PG  G   +  P+  P   +       L   D    
Sbjct: 126  NGTQGAVGFPGPDGYPGLLGPPGLPGQKGS--KGDPVLAPGSFKGMKGDPGLPGLDGITG 183

Query: 1423 TGGAPGSPGGL 1433
              GAPG PG +
Sbjct: 184  PQGAPGFPGAV 194


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.144    0.460 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 123,136,663
Number of Sequences: 37866
Number of extensions: 11152092
Number of successful extensions: 379159
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 622
Number of HSP's successfully gapped in prelim test: 2025
Number of HSP's that attempted gapping in prelim test: 38350
Number of HSP's gapped (non-prelim): 58062
length of query: 1629
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1513
effective length of database: 13,855,062
effective search space: 20962708806
effective search space used: 20962708806
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press