BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|148743793 osteoprotegerin precursor [Homo sapiens] (401 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|148743793 osteoprotegerin precursor [Homo sapiens] 852 0.0 gi|14790170 tumor necrosis factor receptor superfamily, member 6... 172 5e-43 gi|4507585 tumor necrosis factor receptor superfamily, member 6b... 172 5e-43 gi|4507577 tumor necrosis factor receptor 2 precursor [Homo sapi... 128 1e-29 gi|7657039 tumor necrosis factor receptor superfamily, member 21... 115 9e-26 gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens] 103 3e-22 gi|4507565 tumor necrosis factor receptor superfamily, member 11... 103 4e-22 gi|4505039 lymphotoxin beta receptor [Homo sapiens] 94 3e-19 gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens] 92 1e-18 gi|23200041 tumor necrosis factor receptor superfamily, member 1... 80 2e-15 gi|4505393 nerve growth factor receptor precursor [Homo sapiens] 72 7e-13 gi|5730095 tumor necrosis factor receptor superfamily, member 9 ... 67 4e-11 gi|68348711 tumor necrosis factor receptor superfamily, member 8... 61 2e-09 gi|4507579 tumor necrosis factor receptor superfamily, member 4 ... 61 2e-09 gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapi... 60 3e-09 gi|4507583 tumor necrosis factor receptor superfamily, member 6 ... 59 8e-09 gi|22547121 tumor necrosis factor receptor superfamily, member 1... 58 1e-08 gi|23510423 tumor necrosis factor receptor superfamily, member 6... 57 2e-08 gi|22547108 tumor necrosis factor receptor superfamily, member 1... 57 3e-08 gi|21361086 tumor necrosis factor receptor superfamily, member 1... 53 4e-07 gi|4759246 tumor necrosis factor receptor superfamily, member 18... 50 3e-06 gi|23238197 tumor necrosis factor receptor superfamily, member 1... 50 3e-06 gi|224494019 tumor necrosis factor receptor superfamily, member ... 47 2e-05 gi|23238200 RELT tumor necrosis factor receptor precursor [Homo ... 47 2e-05 gi|21361873 RELT tumor necrosis factor receptor precursor [Homo ... 47 2e-05 gi|23200023 tumor necrosis factor receptor superfamily, member 2... 45 9e-05 gi|23200021 tumor necrosis factor receptor superfamily, member 2... 45 9e-05 gi|89142745 tumor necrosis factor receptor superfamily, member 2... 45 9e-05 gi|4507569 tumor necrosis factor receptor superfamily, member 25... 45 9e-05 gi|224494026 tumor necrosis factor receptor superfamily, member ... 44 3e-04 >gi|148743793 osteoprotegerin precursor [Homo sapiens] Length = 401 Score = 852 bits (2201), Expect = 0.0 Identities = 401/401 (100%), Positives = 401/401 (100%) Query: 1 MNNLLCCALVFLDISIKWTTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWKT 60 MNNLLCCALVFLDISIKWTTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWKT Sbjct: 1 MNNLLCCALVFLDISIKWTTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWKT 60 Query: 61 VCAPCPDHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYLEIEFCLK 120 VCAPCPDHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYLEIEFCLK Sbjct: 61 VCAPCPDHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYLEIEFCLK 120 Query: 121 HRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNAT 180 HRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNAT Sbjct: 121 HRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNAT 180 Query: 181 HDNICSGNSESTQKCGIDVTLCEEAFFRFAVPTKFTPNWLSVLVDNLPGTKVNAESVERI 240 HDNICSGNSESTQKCGIDVTLCEEAFFRFAVPTKFTPNWLSVLVDNLPGTKVNAESVERI Sbjct: 181 HDNICSGNSESTQKCGIDVTLCEEAFFRFAVPTKFTPNWLSVLVDNLPGTKVNAESVERI 240 Query: 241 KRQHSSQEQTFQLLKLWKHQNKDQDIVKKIIQDIDLCENSVQRHIGHANLTFEQLRSLME 300 KRQHSSQEQTFQLLKLWKHQNKDQDIVKKIIQDIDLCENSVQRHIGHANLTFEQLRSLME Sbjct: 241 KRQHSSQEQTFQLLKLWKHQNKDQDIVKKIIQDIDLCENSVQRHIGHANLTFEQLRSLME 300 Query: 301 SLPGKKVGAEDIEKTIKACKPSDQILKLLSLWRIKNGDQDTLKGLMHALKHSKTYHFPKT 360 SLPGKKVGAEDIEKTIKACKPSDQILKLLSLWRIKNGDQDTLKGLMHALKHSKTYHFPKT Sbjct: 301 SLPGKKVGAEDIEKTIKACKPSDQILKLLSLWRIKNGDQDTLKGLMHALKHSKTYHFPKT 360 Query: 361 VTQSLKKTIRFLHSFTMYKLYQKLFLEMIGNQVQSVKISCL 401 VTQSLKKTIRFLHSFTMYKLYQKLFLEMIGNQVQSVKISCL Sbjct: 361 VTQSLKKTIRFLHSFTMYKLYQKLFLEMIGNQVQSVKISCL 401 >gi|14790170 tumor necrosis factor receptor superfamily, member 6b [Homo sapiens] Length = 300 Score = 172 bits (436), Expect = 5e-43 Identities = 77/187 (41%), Positives = 108/187 (57%), Gaps = 5/187 (2%) Query: 26 PKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDHYYTDSWHTSDECLYCSP 85 P Y D ET +L+C +CPPGT++++ C T C PCP +YT W+ + C YC+ Sbjct: 34 PTYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNV 93 Query: 86 VCKELQYVKQECNRTHNRVCECKEGRYLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRC 145 +C E + + C+ THNR C C+ G + FCL+H SCPPG GV+ GTP +NT C+ C Sbjct: 94 LCGEREEEARACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPC 153 Query: 146 PDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNATHDNI---CSGNSESTQKCGIDVTLC 202 P G FS +SS C+ H NC+ GL L G+++HD + C+G ST+ G + C Sbjct: 154 PPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEE--C 211 Query: 203 EEAFFRF 209 E A F Sbjct: 212 ERAVIDF 218 >gi|4507585 tumor necrosis factor receptor superfamily, member 6b [Homo sapiens] Length = 300 Score = 172 bits (436), Expect = 5e-43 Identities = 77/187 (41%), Positives = 108/187 (57%), Gaps = 5/187 (2%) Query: 26 PKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDHYYTDSWHTSDECLYCSP 85 P Y D ET +L+C +CPPGT++++ C T C PCP +YT W+ + C YC+ Sbjct: 34 PTYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNV 93 Query: 86 VCKELQYVKQECNRTHNRVCECKEGRYLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRC 145 +C E + + C+ THNR C C+ G + FCL+H SCPPG GV+ GTP +NT C+ C Sbjct: 94 LCGEREEEARACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPC 153 Query: 146 PDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNATHDNI---CSGNSESTQKCGIDVTLC 202 P G FS +SS C+ H NC+ GL L G+++HD + C+G ST+ G + C Sbjct: 154 PPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEE--C 211 Query: 203 EEAFFRF 209 E A F Sbjct: 212 ERAVIDF 218 >gi|4507577 tumor necrosis factor receptor 2 precursor [Homo sapiens] Length = 461 Score = 128 bits (321), Expect = 1e-29 Identities = 66/166 (39%), Positives = 81/166 (48%), Gaps = 12/166 (7%) Query: 30 HYDEETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDHYYTDSWHTSDECLYCSPVCKE 89 +YD+ Q+ C KC PG + K CT TVC C D YT W+ ECL C C Sbjct: 45 YYDQTA--QMCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSS 102 Query: 90 LQYVKQECNRTHNRVCECKEGRYLEI------EFCLKHRSCPPGFGVVQAGTPERNTVCK 143 Q Q C R NR+C C+ G Y + C R C PGFGV + GT + VCK Sbjct: 103 DQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCK 162 Query: 144 RCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNATHDNICSGNS 189 C G FSN TSS CR H C+V + GNA+ D +C+ S Sbjct: 163 PCAPGTFSNTTSSTDICRPHQICNVVAI----PGNASMDAVCTSTS 204 >gi|7657039 tumor necrosis factor receptor superfamily, member 21 precursor [Homo sapiens] Length = 655 Score = 115 bits (287), Expect = 9e-26 Identities = 56/158 (35%), Positives = 77/158 (48%) Query: 28 YLHYDEETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDHYYTDSWHTSDECLYCSPVC 87 Y H D T L CDKCP GTY+ +HCT VC+ CP +T + ++C CS C Sbjct: 54 YRHVDRATGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPC 113 Query: 88 KELQYVKQECNRTHNRVCECKEGRYLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRCPD 147 K C +R C C G + C H CP G+GV + GT + CK+C Sbjct: 114 PWPMIEKLPCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCAR 173 Query: 148 GFFSNETSSKAPCRKHTNCSVFGLLLTQKGNATHDNIC 185 G FS+ SS C+ +T+C L++ + G DN+C Sbjct: 174 GTFSDVPSSVMKCKAYTDCLSQNLVVIKPGTKETDNVC 211 >gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens] Length = 277 Score = 103 bits (257), Expect = 3e-22 Identities = 56/167 (33%), Positives = 79/167 (47%), Gaps = 8/167 (4%) Query: 25 PPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDHYYTDSWHTSDEC---L 81 PP + + C C PG L CT +T C PC + + D+W+ C Sbjct: 22 PPTACREKQYLINSQCCSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHK 81 Query: 82 YCSPVCKELQYVKQECNRTHNRVCECKEGRYLE---IEFCLKHRSCPPGFGVVQAGTPER 138 YC P V+Q+ + +C C+EG + E C+ HRSC PGFGV Q T Sbjct: 82 YCDPNLG--LRVQQKGTSETDTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQIATGVS 139 Query: 139 NTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNATHDNIC 185 +T+C+ CP GFFSN +S+ C T+C L++ Q G D +C Sbjct: 140 DTICEPCPVGFFSNVSSAFEKCHPWTSCETKDLVVQQAGTNKTDVVC 186 Score = 40.4 bits (93), Expect = 0.003 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 3/81 (3%) Query: 107 CKEGRYLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNC 166 C+E +YL C C PG +V T T C C + F + + + C +H C Sbjct: 26 CREKQYLINSQCCS--LCQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYC 83 Query: 167 SV-FGLLLTQKGNATHDNICS 186 GL + QKG + D IC+ Sbjct: 84 DPNLGLRVQQKGTSETDTICT 104 >gi|4507565 tumor necrosis factor receptor superfamily, member 11a precursor [Homo sapiens] Length = 616 Score = 103 bits (256), Expect = 4e-22 Identities = 64/190 (33%), Positives = 85/190 (44%), Gaps = 13/190 (6%) Query: 4 LLCCALVFLDISIKWTTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWKTVCA 63 LLC L L ++++ T Y H C+KC PG Y+ CT +VC Sbjct: 16 LLCALLARLQVALQIAPPCTSEKHYEHLGR------CCNKCEPGKYMSSKCTTTSDSVCL 69 Query: 64 PCPDHYYTDSWHTSDECLYCSPVC---KELQYVKQECNRTHNRVCECKEGRYL--EIEFC 118 PC Y DSW+ D+CL VC K L V N T R C C G + + E C Sbjct: 70 PCGPDEYLDSWNEEDKCLL-HKVCDTGKALVAVVAG-NSTTPRRCACTAGYHWSQDCECC 127 Query: 119 LKHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGN 178 ++ C PG G ++TVCK C G+FS+ SS CR TNC+ G + G Sbjct: 128 RRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGKRVEHHGT 187 Query: 179 ATHDNICSGN 188 D +CS + Sbjct: 188 EKSDAVCSSS 197 >gi|4505039 lymphotoxin beta receptor [Homo sapiens] Length = 435 Score = 93.6 bits (231), Expect = 3e-19 Identities = 51/165 (30%), Positives = 72/165 (43%), Gaps = 9/165 (5%) Query: 34 ETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDHYYTDSWHTSDECLYCSPVCKELQYV 93 E H++ C +CPPGTY+ C+ TVCA C ++ Y + W+ C C P C + + Sbjct: 52 EPQHRICCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRP-CDPVMGL 110 Query: 94 KQ--ECNRTHNRVCECKEGRY-----LEIEFCLKHRSCPPGF-GVVQAGTPERNTVCKRC 145 ++ C C C+ G + LE C CPPG ++ + N C C Sbjct: 111 EEIAPCTSKRKTQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPC 170 Query: 146 PDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNATHDNICSGNSE 190 G F N +S A C+ HT C GL+ G A D C E Sbjct: 171 KAGHFQNTSSPSARCQPHTRCENQGLVEAAPGTAQSDTTCKNPLE 215 Score = 33.1 bits (74), Expect = 0.46 Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 1/73 (1%) Query: 100 THNRVCECKEGRYLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAP 159 + N+ C +E Y E + + CPPG V + R+TVC C + ++ + Sbjct: 38 SENQTCRDQEKEYYEPQHRICCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTI 97 Query: 160 CRKHTNCS-VFGL 171 C+ C V GL Sbjct: 98 CQLCRPCDPVMGL 110 >gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens] Length = 203 Score = 91.7 bits (226), Expect = 1e-18 Identities = 50/146 (34%), Positives = 69/146 (47%), Gaps = 8/146 (5%) Query: 25 PPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDHYYTDSWHTSDEC---L 81 PP + + C C PG L CT +T C PC + + D+W+ C Sbjct: 22 PPTACREKQYLINSQCCSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHK 81 Query: 82 YCSPVCKELQYVKQECNRTHNRVCECKEGRYLE---IEFCLKHRSCPPGFGVVQAGTPER 138 YC P V+Q+ + +C C+EG + E C+ HRSC PGFGV Q T Sbjct: 82 YCDPNLG--LRVQQKGTSETDTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQIATGVS 139 Query: 139 NTVCKRCPDGFFSNETSSKAPCRKHT 164 +T+C+ CP GFFSN +S+ C T Sbjct: 140 DTICEPCPVGFFSNVSSAFEKCHPWT 165 Score = 40.4 bits (93), Expect = 0.003 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 3/81 (3%) Query: 107 CKEGRYLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNC 166 C+E +YL C C PG +V T T C C + F + + + C +H C Sbjct: 26 CREKQYLINSQCCS--LCQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYC 83 Query: 167 SV-FGLLLTQKGNATHDNICS 186 GL + QKG + D IC+ Sbjct: 84 DPNLGLRVQQKGTSETDTICT 104 >gi|23200041 tumor necrosis factor receptor superfamily, member 14 precursor [Homo sapiens] Length = 283 Score = 80.5 bits (197), Expect = 2e-15 Identities = 47/148 (31%), Positives = 70/148 (47%), Gaps = 13/148 (8%) Query: 41 CDKCPPGTYLKQHCTAKWKTVCAPCPDHYYTDSWHTSDECLYCSPVCKELQYVK--QECN 98 C KC PG +K+ C TVC PCP Y + +CL C +C ++ + C+ Sbjct: 54 CPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQ-MCDPAMGLRASRNCS 112 Query: 99 RTHNRVCECKEGRYLEIE------FCLKHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSN 152 RT N VC C G + ++ C + + PG V + GT ++T+C+ CP G FS Sbjct: 113 RTENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFS- 171 Query: 153 ETSSKAPCRKHTNCSVFGLLLTQKGNAT 180 + C+ T CS L+T+ G T Sbjct: 172 PNGTLEECQHQTKCS---WLVTKAGAGT 196 Score = 40.0 bits (92), Expect = 0.004 Identities = 31/111 (27%), Positives = 44/111 (39%), Gaps = 9/111 (8%) Query: 83 CSPVCKELQYVKQECNRTHNRVCE-CKEGRYLE----IEFCLKHRSCPPGFGVVQAGTPE 137 C P C VK+ C VCE C G Y+ + CL+ + C P G+ + Sbjct: 53 CCPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRASRNCS 112 Query: 138 R--NTVCKRCPDGF-FSNETSSKAPCRKHTNCSVFGLLLTQKGNATHDNIC 185 R N VC P F + A CR + S G + + G + D +C Sbjct: 113 RTENAVCGCSPGHFCIVQDGDHCAACRAYATSSP-GQRVQKGGTESQDTLC 162 >gi|4505393 nerve growth factor receptor precursor [Homo sapiens] Length = 427 Score = 72.4 bits (176), Expect = 7e-13 Identities = 50/161 (31%), Positives = 72/161 (44%), Gaps = 11/161 (6%) Query: 9 LVFLDISIKWTTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDH 68 L+ L +S+ + Y H E C C G + Q C A +TVC PC D Sbjct: 18 LLLLGVSLGGAKEACPTGLYTHSGE------CCKACNLGEGVAQPCGAN-QTVCEPCLDS 70 Query: 69 Y-YTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYLEIEF--CLKHRSCP 125 ++D ++ C C+ C LQ + C + VC C G Y + C R C Sbjct: 71 VTFSDVVSATEPCKPCTE-CVGLQSMSAPCVEADDAVCRCAYGYYQDETTGRCEACRVCE 129 Query: 126 PGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNC 166 G G+V + ++NTVC+ CPDG +S+E + PC T C Sbjct: 130 AGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVC 170 Score = 57.4 bits (137), Expect = 2e-08 Identities = 35/100 (35%), Positives = 50/100 (50%), Gaps = 9/100 (9%) Query: 28 YLHYDEETSHQL-LCDKCPPGTYLKQHCTAKWKTVCAPCPDHYYTDSWHTSDECLYCSPV 86 Y +Y +ET+ + C C G+ L C K TVC CPD Y+D + D CL C+ V Sbjct: 111 YGYYQDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCT-V 169 Query: 87 CKELQYVKQECNRTHNRVCECKEGRYLEIEFCLKHRSCPP 126 C++ + +EC R + CE GR++ RS PP Sbjct: 170 CEDTERQLRECTRWADAECEEIPGRWIT-------RSTPP 202 >gi|5730095 tumor necrosis factor receptor superfamily, member 9 precursor [Homo sapiens] Length = 255 Score = 66.6 bits (161), Expect = 4e-11 Identities = 44/160 (27%), Positives = 71/160 (44%), Gaps = 20/160 (12%) Query: 29 LHYDEETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDHYYTDSW--HTSDECLYCSPV 86 L+++ S Q C CP GT+ C +C+PCP + ++ + T D C C V Sbjct: 16 LNFERTRSLQDPCSNCPAGTF----CDNNRNQICSPCPPNSFSSAGGQRTCDICRQCKGV 71 Query: 87 CKELQYVKQECNRTHNRVCECKEGRYLEIEFC-LKHRSCPPGFGVVQAGTPERNTVCKRC 145 + ++EC+ T N C+C G + C + + C G + + G CK C Sbjct: 72 FR----TRKECSSTSNAECDCTPGFHCLGAGCSMCEQDCKQGQELTKKG-------CKDC 120 Query: 146 PDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNATHDNIC 185 G F+++ + CR TNCS+ G + G D +C Sbjct: 121 CFGTFNDQ--KRGICRPWTNCSLDGKSVLVNGTKERDVVC 158 >gi|68348711 tumor necrosis factor receptor superfamily, member 8 isoform 1 precursor [Homo sapiens] Length = 595 Score = 61.2 bits (147), Expect = 2e-09 Identities = 39/145 (26%), Positives = 61/145 (42%), Gaps = 11/145 (7%) Query: 30 HYDEETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDHYYTDSWHTSDECLYCSPVCKE 89 HY ++ + C +CP G + Q C + C YY D +D C C ++ Sbjct: 35 HYYDKAVRRC-CYRCPMGLFPTQQCPQRPTDCRKQCEPDYYLDE---ADRCTACVTCSRD 90 Query: 90 LQYVKQECNRTHNRVCECKEGRYLEIEF------CLKHRSCPPGFGVVQAGTPERNTVCK 143 K C +RVCEC+ G + C H CP G V GT ++NTVC+ Sbjct: 91 DLVEKTPCAWNSSRVCECRPGMFCSTSAVNSCARCFFHSVCPAGMIVKFPGTAQKNTVCE 150 Query: 144 RCPDGFFSNETSSKAPCRKHTNCSV 168 G S +S C++ ++ ++ Sbjct: 151 PASPG-VSPACASPENCKEPSSGTI 174 Score = 28.9 bits (63), Expect = 8.6 Identities = 20/81 (24%), Positives = 25/81 (30%), Gaps = 3/81 (3%) Query: 46 PGTYLKQHCTAKWKTVCAPCPDHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVC 105 PG Q C C YY D C+ CS ++ K C +R C Sbjct: 225 PGLSPTQPCPEGSGDCRKQCEPDYYLDEAGRCTACVSCS---RDDLVEKTPCAWNSSRTC 281 Query: 106 ECKEGRYLEIEFCLKHRSCPP 126 EC+ G C P Sbjct: 282 ECRPGMICATSATNSRARCVP 302 >gi|4507579 tumor necrosis factor receptor superfamily, member 4 precursor [Homo sapiens] Length = 277 Score = 61.2 bits (147), Expect = 2e-09 Identities = 50/184 (27%), Positives = 69/184 (37%), Gaps = 34/184 (18%) Query: 6 CCALVFLDISIKWTTQETFPPKYLHYDEET--SHQLLCDKCPPGTYLKQHCTAKWKTVCA 63 C AL+ L + + T LH +T S+ C +C PG + C+ TVC Sbjct: 13 CAALLLLGLGLSTVTG-------LHCVGDTYPSNDRCCHECRPGNGMVSRCSRSQNTVCR 65 Query: 64 PCPDHYYTD--SWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYLEIEFCLKH 121 PC +Y D S C +C+ + KQ C T + VC C+ G Sbjct: 66 PCGPGFYNDVVSSKPCKPCTWCN--LRSGSERKQLCTATQDTVCRCRAGTQ-------PL 116 Query: 122 RSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNATH 181 S PG C CP G FS C+ TNC++ G Q + + Sbjct: 117 DSYKPGVD------------CAPCPPGHFS--PGDNQACKPWTNCTLAGKHTLQPASNSS 162 Query: 182 DNIC 185 D IC Sbjct: 163 DAIC 166 Score = 48.1 bits (113), Expect = 1e-05 Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 6/89 (6%) Query: 124 CPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSV-FGLLLTQKGNATHD 182 C PG G+V + +NTVC+ C GF+++ SSK PC+ T C++ G Q AT D Sbjct: 46 CRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSK-PCKPCTWCNLRSGSERKQLCTATQD 104 Query: 183 NICSGNSES----TQKCGIDVTLCEEAFF 207 +C + + + K G+D C F Sbjct: 105 TVCRCRAGTQPLDSYKPGVDCAPCPPGHF 133 >gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapiens] Length = 455 Score = 60.1 bits (144), Expect = 3e-09 Identities = 49/166 (29%), Positives = 71/166 (42%), Gaps = 14/166 (8%) Query: 27 KYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWK-TVCAPCPDHYYTDSWHTSDECLYCSP 85 KY+H ++ + C KC GTYL C + T C C +T S + CL CS Sbjct: 48 KYIH---PQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSK 104 Query: 86 VCKELQYVK-QECNRTHNRVCECKEGRYL-----EIEFCLKHRSCPPGFGVVQAGTPERN 139 KE+ V+ C + VC C++ +Y + C C G V + ++N Sbjct: 105 CRKEMGQVEISSCTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCLNG-TVHLSCQEKQN 163 Query: 140 TVCKRCPDGFF--SNETSSKAPCRKHTNCSVFGLLLTQKGNATHDN 183 TVC C GFF NE S + C+K C+ L + T D+ Sbjct: 164 TVC-TCHAGFFLRENECVSCSNCKKSLECTKLCLPQIENVKGTEDS 208 >gi|4507583 tumor necrosis factor receptor superfamily, member 6 isoform 1 precursor [Homo sapiens] Length = 335 Score = 58.9 bits (141), Expect = 8e-09 Identities = 73/284 (25%), Positives = 107/284 (37%), Gaps = 55/284 (19%) Query: 19 TTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKW-KTVCAPCPD-HYYTDSWHT 76 TT ET + LH+D + H+ CPPG + CT + C PC + YTD H Sbjct: 42 TTVETQNLEGLHHDGQFCHK----PCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHF 97 Query: 77 SDECLYCSPVCKELQYVKQE--CNRTHNRVCECKEGRYLEIEFCLKHRSCPP----GFGV 130 S +C C +C E ++ E C RT N C CK + C C P G+ Sbjct: 98 SSKCRRCR-LCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVC---EHCDPCTKCEHGI 153 Query: 131 VQAGTPERNTVCKRCPDGFFSN------------------ETSSKAPCRKHTNCSVFGLL 172 ++ T NT CK +G SN + CRKH Sbjct: 154 IKECTLTSNTKCKE--EGSRSNLGWLCLLLLPIPLIVWVKRKEVQKTCRKH--------- 202 Query: 173 LTQKGNATHDNICSGNSESTQKCGIDVTLCEEAFFRFAVPTKFTPNWLSVLVDNLPGTKV 232 +K N + N E+ DV L + V T LS + + V Sbjct: 203 --RKENQGSHESPTLNPETVAINLSDVDLSKYITTIAGVMT------LSQVKGFVRKNGV 254 Query: 233 NAESVERIKRQH--SSQEQTFQLLKLWKHQNKDQDIVKKIIQDI 274 N ++ IK + + EQ QLL+ W + ++ +I+D+ Sbjct: 255 NEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGKKEAYDTLIKDL 298 >gi|22547121 tumor necrosis factor receptor superfamily, member 10c precursor [Homo sapiens] Length = 259 Score = 58.2 bits (139), Expect = 1e-08 Identities = 34/113 (30%), Positives = 52/113 (46%), Gaps = 10/113 (8%) Query: 19 TTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDHY-YTDSWHTS 77 T ++ P+ ++ H ++CP G++ +H A C PC + YT++ + Sbjct: 28 TARQEEVPQQTVAPQQQRHSFKGEECPAGSHRSEHTGA-----CNPCTEGVDYTNASNNE 82 Query: 78 DECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYL---EIEFCLKHRSCPPG 127 C C+ VCK Q K C T + VC+CKEG + E C K CP G Sbjct: 83 PSCFPCT-VCKSDQKHKSSCTMTRDTVCQCKEGTFRNENSPEMCRKCSRCPSG 134 >gi|23510423 tumor necrosis factor receptor superfamily, member 6 isoform 3 precursor [Homo sapiens] Length = 220 Score = 57.4 bits (137), Expect = 2e-08 Identities = 43/133 (32%), Positives = 58/133 (43%), Gaps = 16/133 (12%) Query: 19 TTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKW-KTVCAPCPD-HYYTDSWHT 76 TT ET + LH+D + H+ CPPG + CT + C PC + YTD H Sbjct: 42 TTVETQNLEGLHHDGQFCHK----PCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHF 97 Query: 77 SDECLYCSPVCKELQYVKQE--CNRTHNRVCECKEGRYLEIEFCLKHRSCPP----GFGV 130 S +C C +C E ++ E C RT N C CK + C C P G+ Sbjct: 98 SSKCRRCR-LCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVC---EHCDPCTKCEHGI 153 Query: 131 VQAGTPERNTVCK 143 ++ T NT CK Sbjct: 154 IKECTLTSNTKCK 166 >gi|22547108 tumor necrosis factor receptor superfamily, member 10d precursor [Homo sapiens] Length = 386 Score = 57.0 bits (136), Expect = 3e-08 Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 15/136 (11%) Query: 42 DKCPPGTYLKQHCTAKWKTVCAPCPDHY-YTDSWHTSDECLYCSPVCKELQYVKQECNRT 100 ++CP G++ ++ A C PC + YT + + CL C+ VCK Q K C T Sbjct: 81 EECPAGSHRSEYTGA-----CNPCTEGVDYTIASNNLPSCLLCT-VCKSGQTNKSSCTTT 134 Query: 101 HNRVCECKEGRYLE---IEFCLKHRS-CPPGFGVVQAGTPERNTVCKRCPDGFFSNETSS 156 + VC+C++G + + E C R+ CP G V TP + CK + ++ Sbjct: 135 RDTVCQCEKGSFQDKNSPEMCRTCRTGCPRGMVKVSNCTPRSDIKCK----NESAASSTG 190 Query: 157 KAPCRKHTNCSVFGLL 172 K P + T ++ G+L Sbjct: 191 KTPAAEETVTTILGML 206 >gi|21361086 tumor necrosis factor receptor superfamily, member 10a [Homo sapiens] Length = 468 Score = 53.1 bits (126), Expect = 4e-07 Identities = 35/115 (30%), Positives = 52/115 (45%), Gaps = 11/115 (9%) Query: 33 EETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDHY-YTDSWHTSDECLYCSPVCKELQ 91 ++ H L + CPPG++ +H A C C + YT++ + CL C+ CK + Sbjct: 121 QQWEHSPLGELCPPGSHRSEHPGA-----CNRCTEGVGYTNASNNLFACLPCT-ACKSDE 174 Query: 92 YVKQECNRTHNRVCECKEGRYL---EIEFCLK-HRSCPPGFGVVQAGTPERNTVC 142 + C T N C+CK G + E C K R CP G V+ TP + C Sbjct: 175 EERSPCTTTRNTACQCKPGTFRNDNSAEMCRKCSRGCPRGMVKVKDCTPWSDIEC 229 >gi|4759246 tumor necrosis factor receptor superfamily, member 18 isoform 1 precursor [Homo sapiens] Length = 241 Score = 50.4 bits (119), Expect = 3e-06 Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 2/77 (2%) Query: 120 KHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNA 179 +H CPPG GV G C C G FS + C+ T+C+ FG L GN Sbjct: 90 RHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSG--GHEGHCKPWTDCTQFGFLTVFPGNK 147 Query: 180 THDNICSGNSESTQKCG 196 TH+ +C S + G Sbjct: 148 THNAVCVPGSPPAEPLG 164 >gi|23238197 tumor necrosis factor receptor superfamily, member 18 isoform 3 precursor [Homo sapiens] Length = 234 Score = 50.4 bits (119), Expect = 3e-06 Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 2/77 (2%) Query: 120 KHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNA 179 +H CPPG GV G C C G FS + C+ T+C+ FG L GN Sbjct: 90 RHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSG--GHEGHCKPWTDCTQFGFLTVFPGNK 147 Query: 180 THDNICSGNSESTQKCG 196 TH+ +C S + G Sbjct: 148 THNAVCVPGSPPAEPLG 164 >gi|224494019 tumor necrosis factor receptor superfamily, member 10b isoform 1 precursor [Homo sapiens] Length = 440 Score = 47.4 bits (111), Expect = 2e-05 Identities = 39/142 (27%), Positives = 59/142 (41%), Gaps = 18/142 (12%) Query: 44 CPPGTYLKQHCTAKWKTVCAPCP-DHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHN 102 CPPG ++ + C C Y+ W+ CL C+ C + C T N Sbjct: 81 CPPGHHISEDGRD-----CISCKYGQDYSTHWNDLLFCLRCTR-CDSGEVELSPCTTTRN 134 Query: 103 RVCECKEGRYLE---IEFCLKHRS-CPPGFGVVQAGTPERNTVCKRCPDGFFSN------ 152 VC+C+EG + E E C K R+ CP G V TP + C G + Sbjct: 135 TVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKESGTKHSGEVPAV 194 Query: 153 -ETSSKAPCRKHTNCSVFGLLL 173 ET + +P + CS+ G+++ Sbjct: 195 EETVTSSPGTPASPCSLSGIII 216 >gi|23238200 RELT tumor necrosis factor receptor precursor [Homo sapiens] Length = 430 Score = 47.4 bits (111), Expect = 2e-05 Identities = 25/62 (40%), Positives = 33/62 (53%), Gaps = 3/62 (4%) Query: 124 CPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNATHDN 183 CPPG P + T+C+ CP G FS S +PC+ H CS++ L Q G AT D Sbjct: 32 CPPG--EEPDLDPGQGTLCRPCPPGTFSAAWGS-SPCQPHARCSLWRRLEAQVGMATRDT 88 Query: 184 IC 185 +C Sbjct: 89 LC 90 >gi|21361873 RELT tumor necrosis factor receptor precursor [Homo sapiens] Length = 430 Score = 47.4 bits (111), Expect = 2e-05 Identities = 25/62 (40%), Positives = 33/62 (53%), Gaps = 3/62 (4%) Query: 124 CPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNATHDN 183 CPPG P + T+C+ CP G FS S +PC+ H CS++ L Q G AT D Sbjct: 32 CPPG--EEPDLDPGQGTLCRPCPPGTFSAAWGS-SPCQPHARCSLWRRLEAQVGMATRDT 88 Query: 184 IC 185 +C Sbjct: 89 LC 90 >gi|23200023 tumor necrosis factor receptor superfamily, member 25 isoform 3 precursor [Homo sapiens] Length = 380 Score = 45.4 bits (106), Expect = 9e-05 Identities = 34/126 (26%), Positives = 48/126 (38%), Gaps = 15/126 (11%) Query: 41 CDKCPPGTYLKQHCTAK-WKTVCAPCP-DHYYTDSWHTSDECLYCSPVCKE--LQYVKQE 96 C CP G YLK CT + C CP D + H + EC C C E Q + Sbjct: 48 CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQ-ACDEQASQVALEN 106 Query: 97 CNRTHNRVCECKEGRYLEIE----------FCLKHRSCPPGFGVVQAGTPERNTVCKRCP 146 C+ + C CK G ++E + +C C + R+T C C Sbjct: 107 CSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCL 166 Query: 147 DGFFSN 152 GF+ + Sbjct: 167 PGFYEH 172 >gi|23200021 tumor necrosis factor receptor superfamily, member 25 isoform 1 precursor [Homo sapiens] Length = 426 Score = 45.4 bits (106), Expect = 9e-05 Identities = 34/126 (26%), Positives = 48/126 (38%), Gaps = 15/126 (11%) Query: 41 CDKCPPGTYLKQHCTAK-WKTVCAPCP-DHYYTDSWHTSDECLYCSPVCKE--LQYVKQE 96 C CP G YLK CT + C CP D + H + EC C C E Q + Sbjct: 48 CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQ-ACDEQASQVALEN 106 Query: 97 CNRTHNRVCECKEGRYLEIE----------FCLKHRSCPPGFGVVQAGTPERNTVCKRCP 146 C+ + C CK G ++E + +C C + R+T C C Sbjct: 107 CSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCL 166 Query: 147 DGFFSN 152 GF+ + Sbjct: 167 PGFYEH 172 >gi|89142745 tumor necrosis factor receptor superfamily, member 25 isoform 12 precursor [Homo sapiens] Length = 181 Score = 45.4 bits (106), Expect = 9e-05 Identities = 34/126 (26%), Positives = 48/126 (38%), Gaps = 15/126 (11%) Query: 41 CDKCPPGTYLKQHCTAK-WKTVCAPCP-DHYYTDSWHTSDECLYCSPVCKE--LQYVKQE 96 C CP G YLK CT + C CP D + H + EC C C E Q + Sbjct: 48 CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQ-ACDEQASQVALEN 106 Query: 97 CNRTHNRVCECKEGRYLEIE----------FCLKHRSCPPGFGVVQAGTPERNTVCKRCP 146 C+ + C CK G ++E + +C C + R+T C C Sbjct: 107 CSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCL 166 Query: 147 DGFFSN 152 GF+ + Sbjct: 167 PGFYEH 172 >gi|4507569 tumor necrosis factor receptor superfamily, member 25 isoform 2 precursor [Homo sapiens] Length = 417 Score = 45.4 bits (106), Expect = 9e-05 Identities = 34/126 (26%), Positives = 48/126 (38%), Gaps = 15/126 (11%) Query: 41 CDKCPPGTYLKQHCTAK-WKTVCAPCP-DHYYTDSWHTSDECLYCSPVCKE--LQYVKQE 96 C CP G YLK CT + C CP D + H + EC C C E Q + Sbjct: 48 CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQ-ACDEQASQVALEN 106 Query: 97 CNRTHNRVCECKEGRYLEIE----------FCLKHRSCPPGFGVVQAGTPERNTVCKRCP 146 C+ + C CK G ++E + +C C + R+T C C Sbjct: 107 CSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCL 166 Query: 147 DGFFSN 152 GF+ + Sbjct: 167 PGFYEH 172 >gi|224494026 tumor necrosis factor receptor superfamily, member 10b isoform 2 precursor [Homo sapiens] Length = 411 Score = 43.9 bits (102), Expect = 3e-04 Identities = 34/116 (29%), Positives = 46/116 (39%), Gaps = 11/116 (9%) Query: 44 CPPGTYLKQHCTAKWKTVCAPCP-DHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHN 102 CPPG ++ + C C Y+ W+ CL C+ C + C T N Sbjct: 81 CPPGHHISEDGRD-----CISCKYGQDYSTHWNDLLFCLRCTR-CDSGEVELSPCTTTRN 134 Query: 103 RVCECKEGRYLE---IEFCLKHRS-CPPGFGVVQAGTPERNTVCKRCPDGFFSNET 154 VC+C+EG + E E C K R+ CP G V TP + C G T Sbjct: 135 TVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKESGIIIGVT 190 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.134 0.431 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,402,474 Number of Sequences: 37866 Number of extensions: 839429 Number of successful extensions: 2241 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 27 Number of HSP's successfully gapped in prelim test: 88 Number of HSP's that attempted gapping in prelim test: 2001 Number of HSP's gapped (non-prelim): 248 length of query: 401 length of database: 18,247,518 effective HSP length: 104 effective length of query: 297 effective length of database: 14,309,454 effective search space: 4249907838 effective search space used: 4249907838 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.