BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens] (1028 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens] 2122 0.0 gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Hom... 600 e-171 gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [H... 546 e-155 gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Ho... 546 e-155 gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s... 335 1e-91 gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s... 335 1e-91 gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo ... 335 1e-91 gi|154759255 collagen, type XXVIII precursor [Homo sapiens] 333 4e-91 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 312 9e-85 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 311 2e-84 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 309 8e-84 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 309 8e-84 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 308 2e-83 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 305 1e-82 gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 305 1e-82 gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 305 1e-82 gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 305 1e-82 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 303 7e-82 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 303 7e-82 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 303 7e-82 gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 301 3e-81 gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 300 4e-81 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 300 4e-81 gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 300 6e-81 gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 298 1e-80 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 297 3e-80 gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] 297 3e-80 gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] 295 2e-79 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 293 4e-79 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 292 1e-78 >gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens] Length = 1028 Score = 2122 bits (5499), Expect = 0.0 Identities = 1028/1028 (100%), Positives = 1028/1028 (100%) Query: 1 MRAARALLPLLLQACWTAAQDEPETPRAVAFQDCPVDLFFVLDTSESVALRLKPYGALVD 60 MRAARALLPLLLQACWTAAQDEPETPRAVAFQDCPVDLFFVLDTSESVALRLKPYGALVD Sbjct: 1 MRAARALLPLLLQACWTAAQDEPETPRAVAFQDCPVDLFFVLDTSESVALRLKPYGALVD 60 Query: 61 KVKSFTKRFIDNLRDRYYRCDRNLVWNAGALHYSDEVEIIQGLTRMPGGRDALKSSVDAV 120 KVKSFTKRFIDNLRDRYYRCDRNLVWNAGALHYSDEVEIIQGLTRMPGGRDALKSSVDAV Sbjct: 61 KVKSFTKRFIDNLRDRYYRCDRNLVWNAGALHYSDEVEIIQGLTRMPGGRDALKSSVDAV 120 Query: 121 KYFGKGTYTDCAIKKGLEQLLVGGSHLKENKYLIVVTDGHPLEGYKEPCGGLEDAVNEAK 180 KYFGKGTYTDCAIKKGLEQLLVGGSHLKENKYLIVVTDGHPLEGYKEPCGGLEDAVNEAK Sbjct: 121 KYFGKGTYTDCAIKKGLEQLLVGGSHLKENKYLIVVTDGHPLEGYKEPCGGLEDAVNEAK 180 Query: 181 HLGVKVFSVAITPDHLEPRLSIIATDHTYRRNFTAADWGQSRDAEEAISQTIDTIVDMIK 240 HLGVKVFSVAITPDHLEPRLSIIATDHTYRRNFTAADWGQSRDAEEAISQTIDTIVDMIK Sbjct: 181 HLGVKVFSVAITPDHLEPRLSIIATDHTYRRNFTAADWGQSRDAEEAISQTIDTIVDMIK 240 Query: 241 NNVEQVCCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGM 300 NNVEQVCCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGM Sbjct: 241 NNVEQVCCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGM 300 Query: 301 KGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP 360 KGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP Sbjct: 301 KGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP 360 Query: 361 KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA 420 KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA Sbjct: 361 KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA 420 Query: 421 PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480 PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD Sbjct: 421 PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480 Query: 481 EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTK 540 EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTK Sbjct: 481 EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTK 540 Query: 541 GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPDECEILDII 600 GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPDECEILDII Sbjct: 541 GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPDECEILDII 600 Query: 601 MKMCSCCECKCGPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYA 660 MKMCSCCECKCGPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYA Sbjct: 601 MKMCSCCECKCGPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYA 660 Query: 661 GVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPN 720 GVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPN Sbjct: 661 GVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPN 720 Query: 721 NRIALVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPS 780 NRIALVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPS Sbjct: 721 NRIALVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPS 780 Query: 781 QGRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASV 840 QGRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASV Sbjct: 781 QGRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASV 840 Query: 841 GSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTAL 900 GSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTAL Sbjct: 841 GSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTAL 900 Query: 901 ASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQ 960 ASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQ Sbjct: 901 ASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQ 960 Query: 961 EAQRAGIEIFVVVVGRQVNEPHIRVLVTGKTAEYDVAYGESHLFRVPSYQALLRGVFHQT 1020 EAQRAGIEIFVVVVGRQVNEPHIRVLVTGKTAEYDVAYGESHLFRVPSYQALLRGVFHQT Sbjct: 961 EAQRAGIEIFVVVVGRQVNEPHIRVLVTGKTAEYDVAYGESHLFRVPSYQALLRGVFHQT 1020 Query: 1021 VSRKVALG 1028 VSRKVALG Sbjct: 1021 VSRKVALG 1028 >gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Homo sapiens] Length = 1019 Score = 600 bits (1546), Expect = e-171 Identities = 363/985 (36%), Positives = 524/985 (53%), Gaps = 57/985 (5%) Query: 33 DCPVDLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLRDRYYRCDRNLVWNAGALH 92 DCP+ ++FVLDTSESV ++ P L+ +K F +FI L++ +Y L W G LH Sbjct: 42 DCPIHVYFVLDTSESVTMQ-SPTDILLFHMKQFVPQFISQLQNEFYLDQVALSWRYGGLH 100 Query: 93 YSDEVEIIQGLTRMPGG-RDALKSSVDAVKYFGKGTYTDCAIKKGLEQLLVGGSHLKENK 151 +SD+VE+ PG R + ++ + F +GT+TDCA+ EQ+ S + Sbjct: 101 FSDQVEVFSP----PGSDRASFIKNLQGISSFRRGTFTDCALANMTEQIRQDRSKGTVH- 155 Query: 152 YLIVVTDGHPLEGYKEPCGGLEDAVNEAKHLGVKVFSVAITPDHLEPRLSIIA-TDHTYR 210 + +V+TDGH PCGG++ A+ G+++F+VA + E L IA T H Sbjct: 156 FAVVITDGHVTGS---PCGGIKLQAERAREEGIRLFAVAPNQNLKEQGLRDIASTPHELY 212 Query: 211 RNFTAADWGQSRDAEEAISQTIDTIVDMIKNNVEQVCCSFECQPARGPPGLRGDPGFEGE 270 RN A D+ E TI+ I+ ++K+ C C GP G +G G +G Sbjct: 213 RNDYAT---MLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIPGPSGPKGYRGQKGA 269 Query: 271 RGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGV 330 +G G PGE G+ G G PG GP+G+ G KG G +GEKG G G KG G G +G Sbjct: 270 KGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGT 329 Query: 331 DGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGP 390 DG KG++G G PGCKG PG G G PG G PG G +G KG+PG G G PG G Sbjct: 330 DGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGA 389 Query: 391 SGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGP 450 G +G G G PG G G +G PGP G GE G G+ G +G+PG+ GP+G+ G+ GP Sbjct: 390 KGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGP 449 Query: 451 QGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGE 510 +G +G G VG G G+ G GP+G +G G PG +G+RG PG AGP GD G G +G+ Sbjct: 450 EGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGD 509 Query: 511 DGPAG---NGTEGFPGFPGYPGNRGAPGIN---GTKGYPGLKGDEGEAGDPGDDNNDIAP 564 G G G G PG G PG RG G G KG PG KG++GE DPG P Sbjct: 510 PGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPG-------P 562 Query: 565 RGVKGAKGYRGPEGPQGPPGHQGPPGPDECEILDIIMKMCSCCEC--KCGPIDLLFVLDS 622 G G +G RG GP+G PG G PG EC+++ + + C CC+C +CG +D++FV+DS Sbjct: 563 PGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKRCGALDVVFVIDS 622 Query: 623 SESIGLQNFEIAKDFVVKVIDRL---SRDELVKFEPGQSYAGVVQYSHSQMQEHVSLRSP 679 SESIG NF + K+FV+ V++RL ++D K E G + GVVQYSH E + L Sbjct: 623 SESIGYTNFTLEKNFVINVVNRLGAIAKDP--KSETG-TRVGVVQYSHEGTFEAIQLDDE 679 Query: 680 SIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNR---IALVITDGRSDTQR 736 I ++ KEA+K+L+W+AGGT+T AL++ D+L+ S + A+VITDGR D + Sbjct: 680 RIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVFAVVITDGRHDPRD 739 Query: 737 DTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLSLVKENYAEL 796 D L LC + V ++GI D+F S+ L I+C P Q R ++L +++L Sbjct: 740 DDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACD--KPQQVR-NMTL----FSDL 792 Query: 797 LEDAFLKNVTAQICIDKK--CPDYTCPITFS------SPADITILLDGSASVGSHNFDTT 848 + + F+ ++ +C D + CPD C S P DI LLDGS +G NF Sbjct: 793 VAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRPVDIVFLLDGSERLGEQNFHKA 852 Query: 849 KRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASAVDAMD 908 +RF +++A R A R D + RVA++Q+ G G+Q + + N TA+ A++ Sbjct: 853 RRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQ---QVAFPLSHNLTAIHEALETTQ 909 Query: 909 FINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGAT-PAAIEKAVQEAQRAGI 967 ++N + V + + + G A++ L + G T ++ ++ ++ + Sbjct: 910 YLNSFSHVGAGVVHAINAIVRSPRGGARRHAELSFVFLTDGVTGNDSLHESAHSMRKQNV 969 Query: 968 EIFVVVVGRQVNEPHIRVLVTGKTA 992 V+ +G V+ + L G A Sbjct: 970 VPTVLALGSDVDMDVLTTLSLGDRA 994 Score = 35.4 bits (80), Expect = 0.28 Identities = 37/134 (27%), Positives = 62/134 (46%), Gaps = 14/134 (10%) Query: 605 SCCECKCGPIDLLFVLDSSESIGLQN------FEIAKDFVVKVIDRLSRDELVKFEPGQS 658 +C E PI + FVLD+SES+ +Q+ F + K FV + I +L ++E + S Sbjct: 36 NCPEKTDCPIHVYFVLDTSESVTMQSPTDILLFHM-KQFVPQFISQL-QNEFYLDQVALS 93 Query: 659 YAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPS 718 + +Y + V + SP + + ++ + GTFT AL +Q+ Sbjct: 94 W----RYGGLHFSDQVEVFSPPGSDRASFIKNLQGISSFRRGTFTDCALANMTEQIRQDR 149 Query: 719 PNNRI--ALVITDG 730 + A+VITDG Sbjct: 150 SKGTVHFAVVITDG 163 >gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [Homo sapiens] Length = 828 Score = 546 bits (1408), Expect = e-155 Identities = 320/806 (39%), Positives = 446/806 (55%), Gaps = 47/806 (5%) Query: 33 DCPVDLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLRDRYYRCDRNLVWNAGALH 92 DCP+ ++FVLDTSESV ++ P L+ +K F +FI L++ +Y L W G LH Sbjct: 42 DCPIHVYFVLDTSESVTMQ-SPTDILLFHMKQFVPQFISQLQNEFYLDQVALSWRYGGLH 100 Query: 93 YSDEVEIIQGLTRMPGG-RDALKSSVDAVKYFGKGTYTDCAIKKGLEQLLVGGSHLKENK 151 +SD+VE+ PG R + ++ + F +GT+TDCA+ EQ+ S + Sbjct: 101 FSDQVEVFSP----PGSDRASFIKNLQGISSFRRGTFTDCALANMTEQIRQDRSKGTVH- 155 Query: 152 YLIVVTDGHPLEGYKEPCGGLEDAVNEAKHLGVKVFSVAITPDHLEPRLSIIA-TDHTYR 210 + +V+TDGH PCGG++ A+ G+++F+VA + E L IA T H Sbjct: 156 FAVVITDGHVTGS---PCGGIKLQAERAREEGIRLFAVAPNQNLKEQGLRDIASTPHELY 212 Query: 211 RNFTAADWGQSRDAEEAISQTIDTIVDMIKNNVEQVCCSFECQPARGPPGLRGDPGFEGE 270 RN A D+ E TI+ I+ ++K+ C C GP G +G G +G Sbjct: 213 RNDYAT---MLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIPGPSGPKGYRGQKGA 269 Query: 271 RGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGV 330 +G G PGE G+ G G PG GP+G+ G KG G +GEKG G G KG G G +G Sbjct: 270 KGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGT 329 Query: 331 DGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGP 390 DG KG++G G PGCKG PG G G PG G PG G +G KG+PG G G PG G Sbjct: 330 DGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGA 389 Query: 391 SGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGP 450 G +G G G PG G G +G PGP G GE G G+ G +G+PG+ GP+G+ G+ GP Sbjct: 390 KGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGP 449 Query: 451 QGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGE 510 +G +G G VG G G+ G GP+G +G G PG +G+RG PG AGP GD G G +G+ Sbjct: 450 EGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGD 509 Query: 511 DGPAG---NGTEGFPGFPGYPGNRGAPGIN---GTKGYPGLKGDEGEAGDPGDDNNDIAP 564 G G G G PG G PG RG G G KG PG KG++GE DPG P Sbjct: 510 PGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPG-------P 562 Query: 565 RGVKGAKGYRGPEGPQGPPGHQGPPGPDECEILDIIMKMCSCCEC--KCGPIDLLFVLDS 622 G G +G RG GP+G PG G PG EC+++ + + C CC+C +CG +D++FV+DS Sbjct: 563 PGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKRCGALDVVFVIDS 622 Query: 623 SESIGLQNFEIAKDFVVKVIDRL---SRDELVKFEPGQSYAGVVQYSHSQMQEHVSLRSP 679 SESIG NF + K+FV+ V++RL ++D K E G + GVVQYSH E + L Sbjct: 623 SESIGYTNFTLEKNFVINVVNRLGAIAKDP--KSETG-TRVGVVQYSHEGTFEAIQLDDE 679 Query: 680 SIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNR---IALVITDGRSDTQR 736 I ++ KEA+K+L+W+AGGT+T AL++ D+L+ S + A+VITDGR D + Sbjct: 680 RIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVFAVVITDGRHDPRD 739 Query: 737 DTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLSLVKENYAEL 796 D L LC + V ++GI D+F S+ L I+C P Q R ++L +++L Sbjct: 740 DDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACD--KPQQVR-NMTL----FSDL 792 Query: 797 LEDAFLKNVTAQICIDKK--CPDYTC 820 + + F+ ++ +C D + CPD C Sbjct: 793 VAEKFIDDMEDVLCPDPQIVCPDLPC 818 Score = 39.7 bits (91), Expect = 0.015 Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 4/120 (3%) Query: 829 DITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHD--VRVAVVQYSGTGQQRP 886 D+ ++D S S+G NF K F + R L A DP + RV VVQYS G Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNR-LGAIAKDPKSETGTRVGVVQYSHEGTFEA 673 Query: 887 ERASLQFLQNYTALASAVDAMDFINDATDVNDALGYV-TRFYREASSGAAKKRLLLFSDG 945 + + + + ++ AV +++I T AL + R +E+ + ++ +DG Sbjct: 674 IQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVFAVVITDG 733 Score = 35.4 bits (80), Expect = 0.28 Identities = 37/134 (27%), Positives = 62/134 (46%), Gaps = 14/134 (10%) Query: 605 SCCECKCGPIDLLFVLDSSESIGLQN------FEIAKDFVVKVIDRLSRDELVKFEPGQS 658 +C E PI + FVLD+SES+ +Q+ F + K FV + I +L ++E + S Sbjct: 36 NCPEKTDCPIHVYFVLDTSESVTMQSPTDILLFHM-KQFVPQFISQL-QNEFYLDQVALS 93 Query: 659 YAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPS 718 + +Y + V + SP + + ++ + GTFT AL +Q+ Sbjct: 94 W----RYGGLHFSDQVEVFSPPGSDRASFIKNLQGISSFRRGTFTDCALANMTEQIRQDR 149 Query: 719 PNNRI--ALVITDG 730 + A+VITDG Sbjct: 150 SKGTVHFAVVITDG 163 >gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Homo sapiens] Length = 918 Score = 546 bits (1408), Expect = e-155 Identities = 320/806 (39%), Positives = 446/806 (55%), Gaps = 47/806 (5%) Query: 33 DCPVDLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLRDRYYRCDRNLVWNAGALH 92 DCP+ ++FVLDTSESV ++ P L+ +K F +FI L++ +Y L W G LH Sbjct: 42 DCPIHVYFVLDTSESVTMQ-SPTDILLFHMKQFVPQFISQLQNEFYLDQVALSWRYGGLH 100 Query: 93 YSDEVEIIQGLTRMPGG-RDALKSSVDAVKYFGKGTYTDCAIKKGLEQLLVGGSHLKENK 151 +SD+VE+ PG R + ++ + F +GT+TDCA+ EQ+ S + Sbjct: 101 FSDQVEVFSP----PGSDRASFIKNLQGISSFRRGTFTDCALANMTEQIRQDRSKGTVH- 155 Query: 152 YLIVVTDGHPLEGYKEPCGGLEDAVNEAKHLGVKVFSVAITPDHLEPRLSIIA-TDHTYR 210 + +V+TDGH PCGG++ A+ G+++F+VA + E L IA T H Sbjct: 156 FAVVITDGHVTGS---PCGGIKLQAERAREEGIRLFAVAPNQNLKEQGLRDIASTPHELY 212 Query: 211 RNFTAADWGQSRDAEEAISQTIDTIVDMIKNNVEQVCCSFECQPARGPPGLRGDPGFEGE 270 RN A D+ E TI+ I+ ++K+ C C GP G +G G +G Sbjct: 213 RNDYAT---MLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIPGPSGPKGYRGQKGA 269 Query: 271 RGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGV 330 +G G PGE G+ G G PG GP+G+ G KG G +GEKG G G KG G G +G Sbjct: 270 KGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGT 329 Query: 331 DGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGP 390 DG KG++G G PGCKG PG G G PG G PG G +G KG+PG G G PG G Sbjct: 330 DGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGA 389 Query: 391 SGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGP 450 G +G G G PG G G +G PGP G GE G G+ G +G+PG+ GP+G+ G+ GP Sbjct: 390 KGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGP 449 Query: 451 QGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGE 510 +G +G G VG G G+ G GP+G +G G PG +G+RG PG AGP GD G G +G+ Sbjct: 450 EGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGD 509 Query: 511 DGPAG---NGTEGFPGFPGYPGNRGAPGIN---GTKGYPGLKGDEGEAGDPGDDNNDIAP 564 G G G G PG G PG RG G G KG PG KG++GE DPG P Sbjct: 510 PGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPG-------P 562 Query: 565 RGVKGAKGYRGPEGPQGPPGHQGPPGPDECEILDIIMKMCSCCEC--KCGPIDLLFVLDS 622 G G +G RG GP+G PG G PG EC+++ + + C CC+C +CG +D++FV+DS Sbjct: 563 PGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKRCGALDVVFVIDS 622 Query: 623 SESIGLQNFEIAKDFVVKVIDRL---SRDELVKFEPGQSYAGVVQYSHSQMQEHVSLRSP 679 SESIG NF + K+FV+ V++RL ++D K E G + GVVQYSH E + L Sbjct: 623 SESIGYTNFTLEKNFVINVVNRLGAIAKDP--KSETG-TRVGVVQYSHEGTFEAIQLDDE 679 Query: 680 SIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNR---IALVITDGRSDTQR 736 I ++ KEA+K+L+W+AGGT+T AL++ D+L+ S + A+VITDGR D + Sbjct: 680 RIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVFAVVITDGRHDPRD 739 Query: 737 DTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLSLVKENYAEL 796 D L LC + V ++GI D+F S+ L I+C P Q R ++L +++L Sbjct: 740 DDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACD--KPQQVR-NMTL----FSDL 792 Query: 797 LEDAFLKNVTAQICIDKK--CPDYTC 820 + + F+ ++ +C D + CPD C Sbjct: 793 VAEKFIDDMEDVLCPDPQIVCPDLPC 818 Score = 39.7 bits (91), Expect = 0.015 Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 4/120 (3%) Query: 829 DITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHD--VRVAVVQYSGTGQQRP 886 D+ ++D S S+G NF K F + R L A DP + RV VVQYS G Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNR-LGAIAKDPKSETGTRVGVVQYSHEGTFEA 673 Query: 887 ERASLQFLQNYTALASAVDAMDFINDATDVNDALGYV-TRFYREASSGAAKKRLLLFSDG 945 + + + + ++ AV +++I T AL + R +E+ + ++ +DG Sbjct: 674 IQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVFAVVITDG 733 Score = 35.4 bits (80), Expect = 0.28 Identities = 37/134 (27%), Positives = 62/134 (46%), Gaps = 14/134 (10%) Query: 605 SCCECKCGPIDLLFVLDSSESIGLQN------FEIAKDFVVKVIDRLSRDELVKFEPGQS 658 +C E PI + FVLD+SES+ +Q+ F + K FV + I +L ++E + S Sbjct: 36 NCPEKTDCPIHVYFVLDTSESVTMQSPTDILLFHM-KQFVPQFISQL-QNEFYLDQVALS 93 Query: 659 YAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPS 718 + +Y + V + SP + + ++ + GTFT AL +Q+ Sbjct: 94 W----RYGGLHFSDQVEVFSPPGSDRASFIKNLQGISSFRRGTFTDCALANMTEQIRQDR 149 Query: 719 PNNRI--ALVITDG 730 + A+VITDG Sbjct: 150 SKGTVHFAVVITDG 163 >gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo sapiens] Length = 2971 Score = 335 bits (859), Expect = 1e-91 Identities = 252/790 (31%), Positives = 359/790 (45%), Gaps = 72/790 (9%) Query: 235 IVDMIKNNVEQVCCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP 294 + + + N E+ CC C+ G G RG G G +G PG G +G GD G PG+ GP Sbjct: 1811 LAEQLDNIAEKACCGVPCK-CSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGP 1869 Query: 295 VGY---QGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGF 351 G QG +G G RG KGSRG G KGE G+ G+DG+DG G+ G PG G KG+PG Sbjct: 1870 PGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGR 1929 Query: 352 DGIQGPPGPKGDPGAFGLKGEKGEPGAD----GEAGRPGSSGPSGDEGQPGEPGPPGEKG 407 G +GP G KG+ G G++G+ G PG D G G G GP G G+ G PG PGE G Sbjct: 1930 RGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETG 1989 Query: 408 EAGDEGNPGPDGAPGERGGPG------ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVG 461 + G G GP GA G +GGPG E+G RG G GP G PG G QG G G G Sbjct: 1990 KNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGG 2049 Query: 462 VPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGF 521 G PGE G GP G +G+ G PG +G G GP G GD G G E G GF Sbjct: 2050 AAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGF 2109 Query: 522 PGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQG 581 PG+PG GN G PG+NGT G G++G G +G P G+ G KG G GP G Sbjct: 2110 PGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPP----------GIVGQKGDPGYPGPAG 2159 Query: 582 PPGHQGPPGPDECEILDIIMKMCSCC----ECKCGPIDLLFVLDSSESIGLQNFEIAKDF 637 P G++G D+C ++ I C CC EC P +L F LD+SE + F +D Sbjct: 2160 PKGNRG-DSIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVNQDTFGRMRDV 2218 Query: 638 VVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQ-- 695 V+ +++ L+ E P + VV Y++ E +R + L + IK+LQ Sbjct: 2219 VLSIVNDLTIAE--SNCPRGARVAVVTYNNEVTTE---IRFADSKRKSVLLDKIKNLQVA 2273 Query: 696 WMAGGTFTGEALQYTRDQLLPPSPNNRIALVITDGRSDTQRDTTPLNVLCSPGIQVVSVG 755 + A+ + N + + S+T +P L +++ G Sbjct: 2274 LTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTRASP--QLREAVLKLSDAG 2331 Query: 756 IKDVFDFIPGSDQLNVISCQGLAPSQGRPGLSLVKENYAELLEDAFLKNV-TAQICIDKK 814 I +F QL L + G +LV +L + FL+NV T +C+D Sbjct: 2332 ITPLFLTRQEDRQL----INALQINNTAVGHALVLPAGRDLTD--FLENVLTCHVCLDIC 2385 Query: 815 CPDYTCPITFSSPA-------------DITILLDGSASVGSHNFDTTKRFAKRLAERF-L 860 D +C P+ D+ +LD + + F+ K++ L + + Sbjct: 2386 NIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDM 2445 Query: 861 TAGRTDPAHDVRVAVVQYSGTGQQRPERASLQ------FLQNYTALASAVD----AMDFI 910 + H RVAVVQ++ + + + AS+ L +Y + VD M + Sbjct: 2446 SPDPKASQHFARVAVVQHAPS--ESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQL 2503 Query: 911 NDATDVNDALGY-VTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQEAQRAGIEI 969 + A+ Y + + A + K ++L G ++ + +A+ G Sbjct: 2504 QGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFF 2563 Query: 970 FVVVVGRQVN 979 V+ +GR+VN Sbjct: 2564 VVLGIGRKVN 2573 Score = 71.6 bits (174), Expect = 4e-12 Identities = 97/372 (26%), Positives = 141/372 (37%), Gaps = 54/372 (14%) Query: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQS--YAGVVQYSHSQMQE 672 D++F++D S ++GL NF +DF+ KVI RL E GQ V QY+ + E Sbjct: 239 DIVFLVDGSSALGLANFNAIRDFIAKVIQRL--------EIGQDLIQVAVAQYADTVRPE 290 Query: 673 HVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNRIA------LV 726 P+ R V +K L A +TG AL + R+ L S R A LV Sbjct: 291 FYFNTHPTKREVITAVRKMKPLDGSA--LYTGSALDFVRNNLFTSSAGYRAAEGIPKLLV 348 Query: 727 ITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGL 786 + G + P L I ++G K G+DQ L L Sbjct: 349 LITGGKSLDEISQPAQELKRSSIMAFAIGNK-------GADQAE------LEEIAFDSSL 395 Query: 787 SLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHNFD 846 + + L + A + P+ S+ DI LLDGSA+VG NF Sbjct: 396 VFIPAEFRAAPLQGMLPGLLAPLRTLSGTPE-----VHSNKRDIIFLLDGSANVGKTNFP 450 Query: 847 TTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASAVDA 906 + F L L G ++RV +VQ+S T SL Q + + + Sbjct: 451 YVRDFVMNLVNS-LDIGN----DNIRVGLVQFSDT---PVTEFSLNTYQTKSDILGHLRQ 502 Query: 907 MDFI-NDATDVNDALGYV-TRFYREASSGAAKKR----LLLFSDGNSQGATPAAIEKAVQ 960 + + AL YV + EA ++ LLL + G S+ + +A Sbjct: 503 LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSED----SYLQAAN 558 Query: 961 EAQRAGIEIFVV 972 RAGI F V Sbjct: 559 ALTRAGILTFCV 570 Score = 55.8 bits (133), Expect = 2e-07 Identities = 70/305 (22%), Positives = 124/305 (40%), Gaps = 44/305 (14%) Query: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674 D++F++DSSE + F +DFV +++ RL+ P + GVVQ+S+ E Sbjct: 1230 DIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLN------IGPSKVRVGVVQFSNDVFPE-- 1281 Query: 675 SLRSPSIRNVQELKEAIKSLQWMAGGTF-TGEALQYTRDQLLPPSPNNRIA------LVI 727 + R+ + +AI+ L+ G TG+AL++ L S +RI LV+ Sbjct: 1282 -FYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVL 1340 Query: 728 TDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLS 787 G + V+ S GI + VG +++ +L I+ P L Sbjct: 1341 VLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNI-----DRTELQTIT--------NDPRLV 1387 Query: 788 LVKENYAEL--LEDAFLKNVTAQICIDKKCPDYTCPIT--FSSPADITILLDGSASVGSH 843 + EL +E+ + + T P + ADI LLDGS + Sbjct: 1388 FTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRD 1447 Query: 844 NFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASA 903 +F RF + + G ++V +VQY+ + FL++++ Sbjct: 1448 SFQEVLRFVSEIVDTVYEDG-----DSIQVGLVQYNS------DPTDEFFLKDFSTKRQI 1496 Query: 904 VDAMD 908 +DA++ Sbjct: 1497 IDAIN 1501 Score = 52.8 bits (125), Expect = 2e-06 Identities = 89/373 (23%), Positives = 151/373 (40%), Gaps = 47/373 (12%) Query: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674 D++F++D S + G NF + DF+V ++++L Q GVVQ+S + + Sbjct: 36 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKL------PIGTQQIRVGVVQFS-DEPRTMF 88 Query: 675 SLRSPSIRNVQELKEAIKSLQWMAGGTFT--GEALQYTRDQLLPPSPNNRIALVITDGRS 732 SL + S + ++ A+K+L + AGG G AL + + + +R+ Sbjct: 89 SLDTYSTK--AQVLGAVKALGF-AGGELANIGLALDFVVENHFTRAGGSRV--------- 136 Query: 733 DTQRDTTPLNVLCSPG-------IQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPG 785 + + VL S G VV++ VF F G+ + Q +A Sbjct: 137 --EEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVF 194 Query: 786 LSLVKENYAELLEDAFLKNV-TAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHN 844 ++ +L E V AQ I K P + + DI L+DGS+++G N Sbjct: 195 TVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLAN 254 Query: 845 FDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASAV 904 F+ + F ++ +R L G+ ++VAV QY+ T RPE + + Sbjct: 255 FNAIRDFIAKVIQR-LEIGQ----DLIQVAVAQYADT--VRPEFYFNTHPTKREVITAVR 307 Query: 905 DAMDFINDATDVNDALGYVTRFYREASSG-----AAKKRLLLFSDGNSQGATPAAIEKAV 959 A AL +V +S+G K L+L + G S I + Sbjct: 308 KMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLD----EISQPA 363 Query: 960 QEAQRAGIEIFVV 972 QE +R+ I F + Sbjct: 364 QELKRSSIMAFAI 376 Score = 50.8 bits (120), Expect = 6e-06 Identities = 89/358 (24%), Positives = 148/358 (41%), Gaps = 55/358 (15%) Query: 612 GPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQ 671 G D++F++D S+S G + F+ + + +++D L V F+ + V+Q+S Sbjct: 1024 GKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLD----VGFDTTR--VAVIQFSDDPKV 1076 Query: 672 EHVSLRSPSIRNVQELKEAIKSLQWMAGGTFT-GEALQYTRDQLLPPSPNNRIA------ 724 E + L + S ++ E++ A++ L+ G G AL+Y + +RI Sbjct: 1077 EFL-LNAHSSKD--EVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQF 1133 Query: 725 -LVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGR 783 ++I+ G+SD + D P +++ G+ F +DQ ++ L+P Sbjct: 1134 LVLISSGKSDDEVD--------DPAVELKQFGVAP-FTIARNADQEELVKIS-LSPEYV- 1182 Query: 784 PGLSLVKENYAELLEDAFLKNVTA----QICIDKKCPDYTCPITFSSPADITILLDGSAS 839 S+ LE L +T QI Y P S ADI L+D S Sbjct: 1183 --FSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEG 1240 Query: 840 VGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTA 899 V F + F R+ R L G + VRV VVQ+S PE +L+ Y + Sbjct: 1241 VRPDGFAHIRDFVSRIVRR-LNIGPS----KVRVGVVQFS--NDVFPE----FYLKTYRS 1289 Query: 900 LASAVDAMDFI----NDATDVNDALGYVTR--FYREASS---GAAKKRLLLFSDGNSQ 948 A +DA+ + + AL +V R F + A S + L+L G SQ Sbjct: 1290 QAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQ 1347 Score = 47.0 bits (110), Expect = 9e-05 Identities = 65/275 (23%), Positives = 112/275 (40%), Gaps = 42/275 (15%) Query: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674 D++F+LD S ++G NF +DFV+ +++ L G+VQ+S + + E Sbjct: 433 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD------IGNDNIRVGLVQFSDTPVTE-F 485 Query: 675 SLRSPSIRNVQELKEAIKSLQWMAG-GTFTGEALQYTRDQLLPPSPNNRI-------ALV 726 SL + ++ ++ ++ LQ G G TG AL Y + +RI L+ Sbjct: 486 SLNTYQTKS--DILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLL 543 Query: 727 ITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGL 786 +T G+S+ N L GI F G+ Q N + +A P L Sbjct: 544 LTAGQSEDSY-LQAANALTRAGI----------LTFCVGASQANKAELEQIA---FNPSL 589 Query: 787 SLVKENYAEL--LEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHN 844 + ++++ L L ++ +T + + P S DI L DGSA++ Sbjct: 590 VYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQP---ESKRDILFLFDGSANLVG-Q 645 Query: 845 FDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYS 879 F + F ++ + R+AV QYS Sbjct: 646 FPVVRDFLYKIIDEL-----NVKPEGTRIAVAQYS 675 Score = 44.7 bits (104), Expect = 5e-04 Identities = 87/396 (21%), Positives = 160/396 (40%), Gaps = 46/396 (11%) Query: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQS-YAGVVQYSHSQMQEH 673 D++F+LD S + +F+ FV +++D + +E G S G+VQY +S + Sbjct: 1433 DIVFLLDGSINFRRDSFQEVLRFVSEIVDTV-------YEDGDSIQVGLVQY-NSDPTDE 1484 Query: 674 VSLRSPSIRNVQELKEAIKSLQWMAG-GTFTGEALQYTRDQLLPPSPNNR-------IAL 725 L+ S + +++ +AI + + G T L++ R P +R IA Sbjct: 1485 FFLKDFSTK--RQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAF 1542 Query: 726 VITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPG 785 VIT G+S L L G++V +VG++++ G N + + Q Sbjct: 1543 VITGGKSVEDAQDVSL-ALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQ---E 1598 Query: 786 LSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSAS----VG 841 LS + E E L DA + + CP T + D+ + DGS V Sbjct: 1599 LSELSEQVLETLHDAMHETL---------CPGVT-DAAKACNLDVILGFDGSRDQNVFVA 1648 Query: 842 SHNFDT-TKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTAL 900 F++ R+++ + + VRV+VV + +G + F + + Sbjct: 1649 QKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVE----AFDFDEYQPEM 1704 Query: 901 ASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQ 960 M + D L +R++S + K ++ F+DG A + +A + Sbjct: 1705 LEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVKV-VIHFTDG--ADGDLADLHRASE 1761 Query: 961 EAQRAGIEIFVVV-VGRQVNEPHIRVLVTGKTAEYD 995 ++ G+ ++V + R VN + L G+ YD Sbjct: 1762 NLRQEGVRALILVGLERVVNLERLMHLEFGRGFMYD 1797 Score = 40.0 bits (92), Expect = 0.011 Identities = 38/169 (22%), Positives = 75/169 (44%), Gaps = 20/169 (11%) Query: 614 IDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEH 673 ID+ F+LDS+E+ L F K ++ ++ +L K + VVQ++ S+ ++ Sbjct: 2412 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2471 Query: 674 VSLRSPSIR-------NVQELKEAI-KSLQWMAGGTFTGEALQYTRDQLLPPSPNNR--- 722 S+ + + ++L + + + + + G G A++YT + + +PN R Sbjct: 2472 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLK 2531 Query: 723 -IALVITDGRSDTQRDTTP---LNVLCSPGIQVV-----SVGIKDVFDF 762 + L++T + Q + L C VV V IK+V+ F Sbjct: 2532 IVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTF 2580 Score = 34.3 bits (77), Expect = 0.62 Identities = 37/126 (29%), Positives = 54/126 (42%), Gaps = 14/126 (11%) Query: 828 ADITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPE 887 ADI L+DGS + GS NF F L E+ L G +RV VVQ+S + Sbjct: 35 ADIIFLIDGSNNTGSVNFAVILDFLVNLLEK-LPIG----TQQIRVGVVQFS---DEPRT 86 Query: 888 RASLQFLQNYTALASAVDAMDFI-NDATDVNDALGYVTRFYREASSGAAKKR-----LLL 941 SL + AV A+ F + ++ AL +V + + G+ + L+L Sbjct: 87 MFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVL 146 Query: 942 FSDGNS 947 S G S Sbjct: 147 ISAGPS 152 >gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo sapiens] Length = 3177 Score = 335 bits (859), Expect = 1e-91 Identities = 252/790 (31%), Positives = 359/790 (45%), Gaps = 72/790 (9%) Query: 235 IVDMIKNNVEQVCCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP 294 + + + N E+ CC C+ G G RG G G +G PG G +G GD G PG+ GP Sbjct: 2017 LAEQLDNIAEKACCGVPCK-CSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGP 2075 Query: 295 VGY---QGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGF 351 G QG +G G RG KGSRG G KGE G+ G+DG+DG G+ G PG G KG+PG Sbjct: 2076 PGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGR 2135 Query: 352 DGIQGPPGPKGDPGAFGLKGEKGEPGAD----GEAGRPGSSGPSGDEGQPGEPGPPGEKG 407 G +GP G KG+ G G++G+ G PG D G G G GP G G+ G PG PGE G Sbjct: 2136 RGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETG 2195 Query: 408 EAGDEGNPGPDGAPGERGGPG------ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVG 461 + G G GP GA G +GGPG E+G RG G GP G PG G QG G G G Sbjct: 2196 KNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGG 2255 Query: 462 VPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGF 521 G PGE G GP G +G+ G PG +G G GP G GD G G E G GF Sbjct: 2256 AAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGF 2315 Query: 522 PGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQG 581 PG+PG GN G PG+NGT G G++G G +G P G+ G KG G GP G Sbjct: 2316 PGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPP----------GIVGQKGDPGYPGPAG 2365 Query: 582 PPGHQGPPGPDECEILDIIMKMCSCC----ECKCGPIDLLFVLDSSESIGLQNFEIAKDF 637 P G++G D+C ++ I C CC EC P +L F LD+SE + F +D Sbjct: 2366 PKGNRG-DSIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVNQDTFGRMRDV 2424 Query: 638 VVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQ-- 695 V+ +++ L+ E P + VV Y++ E +R + L + IK+LQ Sbjct: 2425 VLSIVNDLTIAE--SNCPRGARVAVVTYNNEVTTE---IRFADSKRKSVLLDKIKNLQVA 2479 Query: 696 WMAGGTFTGEALQYTRDQLLPPSPNNRIALVITDGRSDTQRDTTPLNVLCSPGIQVVSVG 755 + A+ + N + + S+T +P L +++ G Sbjct: 2480 LTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTRASP--QLREAVLKLSDAG 2537 Query: 756 IKDVFDFIPGSDQLNVISCQGLAPSQGRPGLSLVKENYAELLEDAFLKNV-TAQICIDKK 814 I +F QL L + G +LV +L + FL+NV T +C+D Sbjct: 2538 ITPLFLTRQEDRQL----INALQINNTAVGHALVLPAGRDLTD--FLENVLTCHVCLDIC 2591 Query: 815 CPDYTCPITFSSPA-------------DITILLDGSASVGSHNFDTTKRFAKRLAERF-L 860 D +C P+ D+ +LD + + F+ K++ L + + Sbjct: 2592 NIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDM 2651 Query: 861 TAGRTDPAHDVRVAVVQYSGTGQQRPERASLQ------FLQNYTALASAVD----AMDFI 910 + H RVAVVQ++ + + + AS+ L +Y + VD M + Sbjct: 2652 SPDPKASQHFARVAVVQHAPS--ESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQL 2709 Query: 911 NDATDVNDALGY-VTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQEAQRAGIEI 969 + A+ Y + + A + K ++L G ++ + +A+ G Sbjct: 2710 QGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFF 2769 Query: 970 FVVVVGRQVN 979 V+ +GR+VN Sbjct: 2770 VVLGIGRKVN 2779 Score = 71.6 bits (174), Expect = 4e-12 Identities = 97/372 (26%), Positives = 141/372 (37%), Gaps = 54/372 (14%) Query: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQS--YAGVVQYSHSQMQE 672 D++F++D S ++GL NF +DF+ KVI RL E GQ V QY+ + E Sbjct: 445 DIVFLVDGSSALGLANFNAIRDFIAKVIQRL--------EIGQDLIQVAVAQYADTVRPE 496 Query: 673 HVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNRIA------LV 726 P+ R V +K L A +TG AL + R+ L S R A LV Sbjct: 497 FYFNTHPTKREVITAVRKMKPLDGSA--LYTGSALDFVRNNLFTSSAGYRAAEGIPKLLV 554 Query: 727 ITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGL 786 + G + P L I ++G K G+DQ L L Sbjct: 555 LITGGKSLDEISQPAQELKRSSIMAFAIGNK-------GADQAE------LEEIAFDSSL 601 Query: 787 SLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHNFD 846 + + L + A + P+ S+ DI LLDGSA+VG NF Sbjct: 602 VFIPAEFRAAPLQGMLPGLLAPLRTLSGTPE-----VHSNKRDIIFLLDGSANVGKTNFP 656 Query: 847 TTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASAVDA 906 + F L L G ++RV +VQ+S T SL Q + + + Sbjct: 657 YVRDFVMNLVNS-LDIGN----DNIRVGLVQFSDT---PVTEFSLNTYQTKSDILGHLRQ 708 Query: 907 MDFI-NDATDVNDALGYV-TRFYREASSGAAKKR----LLLFSDGNSQGATPAAIEKAVQ 960 + + AL YV + EA ++ LLL + G S+ + +A Sbjct: 709 LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSED----SYLQAAN 764 Query: 961 EAQRAGIEIFVV 972 RAGI F V Sbjct: 765 ALTRAGILTFCV 776 Score = 65.9 bits (159), Expect = 2e-10 Identities = 84/349 (24%), Positives = 147/349 (42%), Gaps = 45/349 (12%) Query: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674 D++F++DSS +IG ++F++ ++F+ V+ L+ E + +VQ++ + H Sbjct: 39 DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGE------NDFHFALVQFNGN---PHT 89 Query: 675 SLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNR-------IALVI 727 + R QE+ I ++ ++ G TG+ L+Y L + +R + +V+ Sbjct: 90 EFLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVL 149 Query: 728 TDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLS 787 TDG S P L S + V ++G++D L I+ + L Sbjct: 150 TDGHSKDGL-ALPSAELKSADVNVFAIGVEDA-----DEGALKEIASEPLNMHM------ 197 Query: 788 LVKENYAEL--LEDAFLKNVTAQICIDKKCPDYTC-PITFSSPADITILLDGSASVGSHN 844 EN+ L + + V + + ++ T IT ADI L+DGS + GS N Sbjct: 198 FNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVN 257 Query: 845 FDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASAV 904 F F L E+ L G +RV VVQ+S + SL + AV Sbjct: 258 FAVILDFLVNLLEK-LPIG----TQQIRVGVVQFS---DEPRTMFSLDTYSTKAQVLGAV 309 Query: 905 DAMDFI-NDATDVNDALGYVTRFYREASSGAAKKR-----LLLFSDGNS 947 A+ F + ++ AL +V + + G+ + L+L S G S Sbjct: 310 KALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPS 358 Score = 55.8 bits (133), Expect = 2e-07 Identities = 70/305 (22%), Positives = 124/305 (40%), Gaps = 44/305 (14%) Query: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674 D++F++DSSE + F +DFV +++ RL+ P + GVVQ+S+ E Sbjct: 1436 DIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLN------IGPSKVRVGVVQFSNDVFPE-- 1487 Query: 675 SLRSPSIRNVQELKEAIKSLQWMAGGTF-TGEALQYTRDQLLPPSPNNRIA------LVI 727 + R+ + +AI+ L+ G TG+AL++ L S +RI LV+ Sbjct: 1488 -FYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVL 1546 Query: 728 TDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLS 787 G + V+ S GI + VG +++ +L I+ P L Sbjct: 1547 VLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNI-----DRTELQTIT--------NDPRLV 1593 Query: 788 LVKENYAEL--LEDAFLKNVTAQICIDKKCPDYTCPIT--FSSPADITILLDGSASVGSH 843 + EL +E+ + + T P + ADI LLDGS + Sbjct: 1594 FTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRD 1653 Query: 844 NFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASA 903 +F RF + + G ++V +VQY+ + FL++++ Sbjct: 1654 SFQEVLRFVSEIVDTVYEDG-----DSIQVGLVQYNS------DPTDEFFLKDFSTKRQI 1702 Query: 904 VDAMD 908 +DA++ Sbjct: 1703 IDAIN 1707 Score = 52.8 bits (125), Expect = 2e-06 Identities = 89/373 (23%), Positives = 151/373 (40%), Gaps = 47/373 (12%) Query: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674 D++F++D S + G NF + DF+V ++++L Q GVVQ+S + + Sbjct: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKL------PIGTQQIRVGVVQFS-DEPRTMF 294 Query: 675 SLRSPSIRNVQELKEAIKSLQWMAGGTFT--GEALQYTRDQLLPPSPNNRIALVITDGRS 732 SL + S + ++ A+K+L + AGG G AL + + + +R+ Sbjct: 295 SLDTYSTK--AQVLGAVKALGF-AGGELANIGLALDFVVENHFTRAGGSRV--------- 342 Query: 733 DTQRDTTPLNVLCSPG-------IQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPG 785 + + VL S G VV++ VF F G+ + Q +A Sbjct: 343 --EEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVF 400 Query: 786 LSLVKENYAELLEDAFLKNV-TAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHN 844 ++ +L E V AQ I K P + + DI L+DGS+++G N Sbjct: 401 TVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLAN 460 Query: 845 FDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASAV 904 F+ + F ++ +R L G+ ++VAV QY+ T RPE + + Sbjct: 461 FNAIRDFIAKVIQR-LEIGQ----DLIQVAVAQYADT--VRPEFYFNTHPTKREVITAVR 513 Query: 905 DAMDFINDATDVNDALGYVTRFYREASSG-----AAKKRLLLFSDGNSQGATPAAIEKAV 959 A AL +V +S+G K L+L + G S I + Sbjct: 514 KMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLD----EISQPA 569 Query: 960 QEAQRAGIEIFVV 972 QE +R+ I F + Sbjct: 570 QELKRSSIMAFAI 582 Score = 50.8 bits (120), Expect = 6e-06 Identities = 89/358 (24%), Positives = 148/358 (41%), Gaps = 55/358 (15%) Query: 612 GPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQ 671 G D++F++D S+S G + F+ + + +++D L V F+ + V+Q+S Sbjct: 1230 GKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLD----VGFDTTR--VAVIQFSDDPKV 1282 Query: 672 EHVSLRSPSIRNVQELKEAIKSLQWMAGGTFT-GEALQYTRDQLLPPSPNNRIA------ 724 E + L + S ++ E++ A++ L+ G G AL+Y + +RI Sbjct: 1283 EFL-LNAHSSKD--EVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQF 1339 Query: 725 -LVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGR 783 ++I+ G+SD + D P +++ G+ F +DQ ++ L+P Sbjct: 1340 LVLISSGKSDDEVD--------DPAVELKQFGVAP-FTIARNADQEELVKIS-LSPEYV- 1388 Query: 784 PGLSLVKENYAELLEDAFLKNVTA----QICIDKKCPDYTCPITFSSPADITILLDGSAS 839 S+ LE L +T QI Y P S ADI L+D S Sbjct: 1389 --FSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEG 1446 Query: 840 VGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTA 899 V F + F R+ R L G + VRV VVQ+S PE +L+ Y + Sbjct: 1447 VRPDGFAHIRDFVSRIVRR-LNIGPS----KVRVGVVQFS--NDVFPE----FYLKTYRS 1495 Query: 900 LASAVDAMDFI----NDATDVNDALGYVTR--FYREASS---GAAKKRLLLFSDGNSQ 948 A +DA+ + + AL +V R F + A S + L+L G SQ Sbjct: 1496 QAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQ 1553 Score = 47.0 bits (110), Expect = 9e-05 Identities = 65/275 (23%), Positives = 112/275 (40%), Gaps = 42/275 (15%) Query: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674 D++F+LD S ++G NF +DFV+ +++ L G+VQ+S + + E Sbjct: 639 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD------IGNDNIRVGLVQFSDTPVTE-F 691 Query: 675 SLRSPSIRNVQELKEAIKSLQWMAG-GTFTGEALQYTRDQLLPPSPNNRI-------ALV 726 SL + ++ ++ ++ LQ G G TG AL Y + +RI L+ Sbjct: 692 SLNTYQTKS--DILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLL 749 Query: 727 ITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGL 786 +T G+S+ N L GI F G+ Q N + +A P L Sbjct: 750 LTAGQSEDSY-LQAANALTRAGI----------LTFCVGASQANKAELEQIA---FNPSL 795 Query: 787 SLVKENYAEL--LEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHN 844 + ++++ L L ++ +T + + P S DI L DGSA++ Sbjct: 796 VYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQP---ESKRDILFLFDGSANLVG-Q 851 Query: 845 FDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYS 879 F + F ++ + R+AV QYS Sbjct: 852 FPVVRDFLYKIIDEL-----NVKPEGTRIAVAQYS 881 Score = 44.7 bits (104), Expect = 5e-04 Identities = 87/396 (21%), Positives = 160/396 (40%), Gaps = 46/396 (11%) Query: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQS-YAGVVQYSHSQMQEH 673 D++F+LD S + +F+ FV +++D + +E G S G+VQY +S + Sbjct: 1639 DIVFLLDGSINFRRDSFQEVLRFVSEIVDTV-------YEDGDSIQVGLVQY-NSDPTDE 1690 Query: 674 VSLRSPSIRNVQELKEAIKSLQWMAG-GTFTGEALQYTRDQLLPPSPNNR-------IAL 725 L+ S + +++ +AI + + G T L++ R P +R IA Sbjct: 1691 FFLKDFSTK--RQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAF 1748 Query: 726 VITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPG 785 VIT G+S L L G++V +VG++++ G N + + Q Sbjct: 1749 VITGGKSVEDAQDVSL-ALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQ---E 1804 Query: 786 LSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSAS----VG 841 LS + E E L DA + + CP T + D+ + DGS V Sbjct: 1805 LSELSEQVLETLHDAMHETL---------CPGVT-DAAKACNLDVILGFDGSRDQNVFVA 1854 Query: 842 SHNFDT-TKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTAL 900 F++ R+++ + + VRV+VV + +G + F + + Sbjct: 1855 QKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVE----AFDFDEYQPEM 1910 Query: 901 ASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQ 960 M + D L +R++S + K ++ F+DG A + +A + Sbjct: 1911 LEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVKV-VIHFTDG--ADGDLADLHRASE 1967 Query: 961 EAQRAGIEIFVVV-VGRQVNEPHIRVLVTGKTAEYD 995 ++ G+ ++V + R VN + L G+ YD Sbjct: 1968 NLRQEGVRALILVGLERVVNLERLMHLEFGRGFMYD 2003 Score = 40.0 bits (92), Expect = 0.011 Identities = 38/169 (22%), Positives = 75/169 (44%), Gaps = 20/169 (11%) Query: 614 IDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEH 673 ID+ F+LDS+E+ L F K ++ ++ +L K + VVQ++ S+ ++ Sbjct: 2618 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2677 Query: 674 VSLRSPSIR-------NVQELKEAI-KSLQWMAGGTFTGEALQYTRDQLLPPSPNNR--- 722 S+ + + ++L + + + + + G G A++YT + + +PN R Sbjct: 2678 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLK 2737 Query: 723 -IALVITDGRSDTQRDTTP---LNVLCSPGIQVV-----SVGIKDVFDF 762 + L++T + Q + L C VV V IK+V+ F Sbjct: 2738 IVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTF 2786 Score = 33.5 bits (75), Expect = 1.1 Identities = 33/154 (21%), Positives = 66/154 (42%), Gaps = 21/154 (13%) Query: 828 ADITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPE 887 ADI L+D S ++G +F + F + + L G +D A+VQ++G Sbjct: 38 ADIIFLVDSSWTIGEEHFQLVREFLYDVV-KSLAVGE----NDFHFALVQFNGNPH---T 89 Query: 888 RASLQFLQNYTALASAVDAMDFINDATDVNDALGYVTRFYREASSGA-----AKKRLLLF 942 L + + S + M +I L Y+ + + ++G+ + +++ Sbjct: 90 EFLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVL 149 Query: 943 SDGNSQG--ATPAAIEKAVQEAQRAGIEIFVVVV 974 +DG+S+ A P+A E + A + +F + V Sbjct: 150 TDGHSKDGLALPSA------ELKSADVNVFAIGV 177 >gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo sapiens] Length = 2570 Score = 335 bits (859), Expect = 1e-91 Identities = 252/790 (31%), Positives = 359/790 (45%), Gaps = 72/790 (9%) Query: 235 IVDMIKNNVEQVCCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP 294 + + + N E+ CC C+ G G RG G G +G PG G +G GD G PG+ GP Sbjct: 1410 LAEQLDNIAEKACCGVPCK-CSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGP 1468 Query: 295 VGY---QGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGF 351 G QG +G G RG KGSRG G KGE G+ G+DG+DG G+ G PG G KG+PG Sbjct: 1469 PGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGR 1528 Query: 352 DGIQGPPGPKGDPGAFGLKGEKGEPGAD----GEAGRPGSSGPSGDEGQPGEPGPPGEKG 407 G +GP G KG+ G G++G+ G PG D G G G GP G G+ G PG PGE G Sbjct: 1529 RGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETG 1588 Query: 408 EAGDEGNPGPDGAPGERGGPG------ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVG 461 + G G GP GA G +GGPG E+G RG G GP G PG G QG G G G Sbjct: 1589 KNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGG 1648 Query: 462 VPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGF 521 G PGE G GP G +G+ G PG +G G GP G GD G G E G GF Sbjct: 1649 AAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGF 1708 Query: 522 PGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQG 581 PG+PG GN G PG+NGT G G++G G +G P G+ G KG G GP G Sbjct: 1709 PGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPP----------GIVGQKGDPGYPGPAG 1758 Query: 582 PPGHQGPPGPDECEILDIIMKMCSCC----ECKCGPIDLLFVLDSSESIGLQNFEIAKDF 637 P G++G D+C ++ I C CC EC P +L F LD+SE + F +D Sbjct: 1759 PKGNRG-DSIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVNQDTFGRMRDV 1817 Query: 638 VVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQ-- 695 V+ +++ L+ E P + VV Y++ E +R + L + IK+LQ Sbjct: 1818 VLSIVNDLTIAE--SNCPRGARVAVVTYNNEVTTE---IRFADSKRKSVLLDKIKNLQVA 1872 Query: 696 WMAGGTFTGEALQYTRDQLLPPSPNNRIALVITDGRSDTQRDTTPLNVLCSPGIQVVSVG 755 + A+ + N + + S+T +P L +++ G Sbjct: 1873 LTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTRASP--QLREAVLKLSDAG 1930 Query: 756 IKDVFDFIPGSDQLNVISCQGLAPSQGRPGLSLVKENYAELLEDAFLKNV-TAQICIDKK 814 I +F QL L + G +LV +L + FL+NV T +C+D Sbjct: 1931 ITPLFLTRQEDRQL----INALQINNTAVGHALVLPAGRDLTD--FLENVLTCHVCLDIC 1984 Query: 815 CPDYTCPITFSSPA-------------DITILLDGSASVGSHNFDTTKRFAKRLAERF-L 860 D +C P+ D+ +LD + + F+ K++ L + + Sbjct: 1985 NIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDM 2044 Query: 861 TAGRTDPAHDVRVAVVQYSGTGQQRPERASLQ------FLQNYTALASAVD----AMDFI 910 + H RVAVVQ++ + + + AS+ L +Y + VD M + Sbjct: 2045 SPDPKASQHFARVAVVQHAPS--ESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQL 2102 Query: 911 NDATDVNDALGY-VTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQEAQRAGIEI 969 + A+ Y + + A + K ++L G ++ + +A+ G Sbjct: 2103 QGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFF 2162 Query: 970 FVVVVGRQVN 979 V+ +GR+VN Sbjct: 2163 VVLGIGRKVN 2172 Score = 56.6 bits (135), Expect = 1e-07 Identities = 69/273 (25%), Positives = 101/273 (36%), Gaps = 44/273 (16%) Query: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQS--YAGVVQYSHSQMQE 672 D++F++D S ++GL NF +DF+ KVI RL E GQ V QY+ + E Sbjct: 38 DIVFLVDGSSALGLANFNAIRDFIAKVIQRL--------EIGQDLIQVAVAQYADTVRPE 89 Query: 673 HVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNRIA------LV 726 P+ R V +K L A +TG AL + R+ L S R A LV Sbjct: 90 FYFNTHPTKREVITAVRKMKPLDGSA--LYTGSALDFVRNNLFTSSAGYRAAEGIPKLLV 147 Query: 727 ITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGL 786 + G + P L I ++G K G+DQ L L Sbjct: 148 LITGGKSLDEISQPAQELKRSSIMAFAIGNK-------GADQAE------LEEIAFDSSL 194 Query: 787 SLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHNFD 846 + + L + A + P+ S DI L DGSA++ F Sbjct: 195 VFIPAEFRAAPLQGMLPGLLAPLRTLSGTPE-------ESKRDILFLFDGSANLVG-QFP 246 Query: 847 TTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYS 879 + F ++ + R+AV QYS Sbjct: 247 VVRDFLYKIIDEL-----NVKPEGTRIAVAQYS 274 Score = 56.6 bits (135), Expect = 1e-07 Identities = 88/335 (26%), Positives = 135/335 (40%), Gaps = 60/335 (17%) Query: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYS-----HSQ 669 D+LF+ D S ++ + F + +DF+ K+ID L+ +P + V QYS S+ Sbjct: 230 DILFLFDGSANL-VGQFPVVRDFLYKIIDELN------VKPEGTRIAVAQYSDDVKVESR 282 Query: 670 MQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFT-GEALQYTRDQLLPPSPNNRI----- 723 EH S P I N+ +K ++ G G AL Y + + S +RI Sbjct: 283 FDEHQS--KPEILNL------VKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVL 334 Query: 724 --ALVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQ 781 +++ GRS + D P + L G+ K+ P + V+S + ++ Sbjct: 335 QFLVLLVAGRSSDRVD-GPASNLKQSGVVPFIFQAKNA---DPAELEQIVLSPAFILAAE 390 Query: 782 GRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASVG 841 P + + LL K P S D+ LLDGS V Sbjct: 391 SLPKIGDLHPQIVNLL----------------KSVHNGAPAPVSGEKDVVFLLDGSEGVR 434 Query: 842 SHNFDTTKRFAKRLAERFLTAGRTDPAHD-VRVAVVQYSGTGQQRPERASLQFLQNYTAL 900 S F K F +R+ E D D VRVAVVQYS + RPE L N + Sbjct: 435 S-GFPLLKEFVQRVVESL------DVGQDRVRVAVVQYS--DRTRPE-FYLNSYMNKQDV 484 Query: 901 ASAVDAMDFINDAT-DVNDALGYVTRFYREASSGA 934 +AV + + T + AL +V R +S+G+ Sbjct: 485 VNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGS 519 Score = 55.8 bits (133), Expect = 2e-07 Identities = 70/305 (22%), Positives = 124/305 (40%), Gaps = 44/305 (14%) Query: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674 D++F++DSSE + F +DFV +++ RL+ P + GVVQ+S+ E Sbjct: 829 DIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLN------IGPSKVRVGVVQFSNDVFPE-- 880 Query: 675 SLRSPSIRNVQELKEAIKSLQWMAGGTF-TGEALQYTRDQLLPPSPNNRIA------LVI 727 + R+ + +AI+ L+ G TG+AL++ L S +RI LV+ Sbjct: 881 -FYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVL 939 Query: 728 TDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLS 787 G + V+ S GI + VG +++ +L I+ P L Sbjct: 940 VLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNI-----DRTELQTIT--------NDPRLV 986 Query: 788 LVKENYAEL--LEDAFLKNVTAQICIDKKCPDYTCPIT--FSSPADITILLDGSASVGSH 843 + EL +E+ + + T P + ADI LLDGS + Sbjct: 987 FTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRD 1046 Query: 844 NFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASA 903 +F RF + + G ++V +VQY+ + FL++++ Sbjct: 1047 SFQEVLRFVSEIVDTVYEDG-----DSIQVGLVQYNS------DPTDEFFLKDFSTKRQI 1095 Query: 904 VDAMD 908 +DA++ Sbjct: 1096 IDAIN 1100 Score = 50.8 bits (120), Expect = 6e-06 Identities = 89/358 (24%), Positives = 148/358 (41%), Gaps = 55/358 (15%) Query: 612 GPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQ 671 G D++F++D S+S G + F+ + + +++D L V F+ + V+Q+S Sbjct: 623 GKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLD----VGFDTTR--VAVIQFSDDPKV 675 Query: 672 EHVSLRSPSIRNVQELKEAIKSLQWMAGGTFT-GEALQYTRDQLLPPSPNNRIA------ 724 E + L + S ++ E++ A++ L+ G G AL+Y + +RI Sbjct: 676 EFL-LNAHSSKD--EVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQF 732 Query: 725 -LVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGR 783 ++I+ G+SD + D P +++ G+ F +DQ ++ L+P Sbjct: 733 LVLISSGKSDDEVD--------DPAVELKQFGVAP-FTIARNADQEELVKIS-LSPEYV- 781 Query: 784 PGLSLVKENYAELLEDAFLKNVTA----QICIDKKCPDYTCPITFSSPADITILLDGSAS 839 S+ LE L +T QI Y P S ADI L+D S Sbjct: 782 --FSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEG 839 Query: 840 VGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTA 899 V F + F R+ R L G + VRV VVQ+S PE +L+ Y + Sbjct: 840 VRPDGFAHIRDFVSRIVRR-LNIGPS----KVRVGVVQFS--NDVFPE----FYLKTYRS 888 Query: 900 LASAVDAMDFI----NDATDVNDALGYVTR--FYREASS---GAAKKRLLLFSDGNSQ 948 A +DA+ + + AL +V R F + A S + L+L G SQ Sbjct: 889 QAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQ 946 Score = 44.7 bits (104), Expect = 5e-04 Identities = 87/396 (21%), Positives = 160/396 (40%), Gaps = 46/396 (11%) Query: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQS-YAGVVQYSHSQMQEH 673 D++F+LD S + +F+ FV +++D + +E G S G+VQY +S + Sbjct: 1032 DIVFLLDGSINFRRDSFQEVLRFVSEIVDTV-------YEDGDSIQVGLVQY-NSDPTDE 1083 Query: 674 VSLRSPSIRNVQELKEAIKSLQWMAG-GTFTGEALQYTRDQLLPPSPNNR-------IAL 725 L+ S + +++ +AI + + G T L++ R P +R IA Sbjct: 1084 FFLKDFSTK--RQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAF 1141 Query: 726 VITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPG 785 VIT G+S L L G++V +VG++++ G N + + Q Sbjct: 1142 VITGGKSVEDAQDVSL-ALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQ---E 1197 Query: 786 LSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSAS----VG 841 LS + E E L DA + + CP T + D+ + DGS V Sbjct: 1198 LSELSEQVLETLHDAMHETL---------CPGVT-DAAKACNLDVILGFDGSRDQNVFVA 1247 Query: 842 SHNFDT-TKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTAL 900 F++ R+++ + + VRV+VV + +G + F + + Sbjct: 1248 QKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVE----AFDFDEYQPEM 1303 Query: 901 ASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQ 960 M + D L +R++S + K ++ F+DG A + +A + Sbjct: 1304 LEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVKV-VIHFTDG--ADGDLADLHRASE 1360 Query: 961 EAQRAGIEIFVVV-VGRQVNEPHIRVLVTGKTAEYD 995 ++ G+ ++V + R VN + L G+ YD Sbjct: 1361 NLRQEGVRALILVGLERVVNLERLMHLEFGRGFMYD 1396 Score = 40.0 bits (92), Expect = 0.011 Identities = 38/169 (22%), Positives = 75/169 (44%), Gaps = 20/169 (11%) Query: 614 IDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEH 673 ID+ F+LDS+E+ L F K ++ ++ +L K + VVQ++ S+ ++ Sbjct: 2011 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2070 Query: 674 VSLRSPSIR-------NVQELKEAI-KSLQWMAGGTFTGEALQYTRDQLLPPSPNNR--- 722 S+ + + ++L + + + + + G G A++YT + + +PN R Sbjct: 2071 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLK 2130 Query: 723 -IALVITDGRSDTQRDTTP---LNVLCSPGIQVV-----SVGIKDVFDF 762 + L++T + Q + L C VV V IK+V+ F Sbjct: 2131 IVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTF 2179 Score = 35.0 bits (79), Expect = 0.36 Identities = 39/149 (26%), Positives = 63/149 (42%), Gaps = 16/149 (10%) Query: 829 DITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPER 888 DI L+DGS+++G NF+ + F ++ +R L G+ ++VAV QY+ T RPE Sbjct: 38 DIVFLVDGSSALGLANFNAIRDFIAKVIQR-LEIGQ----DLIQVAVAQYADT--VRPEF 90 Query: 889 ASLQFLQNYTALASAVDAMDFINDATDVNDALGYVTRFYREASSG-----AAKKRLLLFS 943 + + A AL +V +S+G K L+L + Sbjct: 91 YFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLIT 150 Query: 944 DGNSQGATPAAIEKAVQEAQRAGIEIFVV 972 G S I + QE +R+ I F + Sbjct: 151 GGKSLD----EISQPAQELKRSSIMAFAI 175 >gi|154759255 collagen, type XXVIII precursor [Homo sapiens] Length = 1125 Score = 333 bits (855), Expect = 4e-91 Identities = 217/538 (40%), Positives = 287/538 (53%), Gaps = 72/538 (13%) Query: 257 GPPGLRGDPGFEGERGKPG--LPGEKGEAGDPGRPGDLGPVGYQGM--KGEKGSRGEKGS 312 G PG RG G GERG PG PG KGE G G GP G QG+ KGEKG G G Sbjct: 386 GQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEG---PTGPQGLQGLSIKGEKGDIGPVGP 442 Query: 313 RGPKGYKG--EKGKRGIDGVDGVKGEMGYPG--LPGCKGSPGFDGIQGP--------PGP 360 +GP G G +G++GI G G G G G LPG KG G G GP GP Sbjct: 443 QGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGP 502 Query: 361 KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA 420 KG+PG+ GL G+ G PG DG AG+ G +G G G G PG G+ G GDEG G G Sbjct: 503 KGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK-GQPGPKGDEGKKGSKGN 561 Query: 421 PGERGGPGERGPRGTPGTRGPRGDPGEA--GPQGDQGREGPVGVPGDPGEAGPI--GPKG 476 G+RG PG GP+G PG GP G PG + GP G +G G G+PG GE G GPKG Sbjct: 562 QGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKG 621 Query: 477 YRGDEGP-----------PGSEGARGAPGPAGP-----------PGDPGLMGERGEDGPA 514 +G GP PG G RG PGP GP G+PG+ G G GP Sbjct: 622 VQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPR 681 Query: 515 GNGTEG---------FPGFPGYPG--NRGAPGINGTKGYPGLKGDEGEA--GDPGD--DN 559 G GT+G PG PG PG ++G G G +G+PG KG G G G+ + Sbjct: 682 GVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGER 741 Query: 560 NDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPDECEILDIIMKMCSCC-ECKCGPIDLLF 618 D+ +G KG G G G QG G +G G + EI+ +I ++C C +CK P++L+F Sbjct: 742 GDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLITEICGCGPKCKETPLELVF 801 Query: 619 VLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHVSLRS 678 V+DSSES+G +NF+I K+FV + DR++ D + G++ YSH ++++ +L+ Sbjct: 802 VIDSSESVGPENFQIIKNFVKTMADRVALDLAT------ARIGIINYSH-KVEKVANLKQ 854 Query: 679 PSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPN-NRIALVITDGRSDTQ 735 S ++ + K A+ ++Q++ GT+T ALQ D P ++ALVITDG++D++ Sbjct: 855 FSSKD--DFKLAVDNMQYLGEGTYTATALQAANDMFEDARPGVKKVALVITDGQTDSR 910 Score = 307 bits (786), Expect = 4e-83 Identities = 216/593 (36%), Positives = 291/593 (49%), Gaps = 89/593 (15%) Query: 34 CPVDLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLRDRYYRCD--RNLVWNA--G 89 C +D+ F++D+SES + AL DK K F +D+L D+ ++ R+L ++ Sbjct: 45 CFIDIVFIVDSSESSKI------ALFDKQKDF----VDSLSDKIFQLTPGRSLEYDIKLA 94 Query: 90 ALHYSDEVEIIQGLTRMPGGRDALKSSVDAVKYFGKGTYTDCAIKKGLEQLLVGGSHLKE 149 AL +S V+I + K V ++ G+GT++ AI +LL Sbjct: 95 ALQFSSSVQIDPPFSSWKD-LQTFKQKVKSMNLIGQGTFSYYAISNAT-RLLKREGRKDG 152 Query: 150 NKYLIVVTDG--HPLEGYKEPCGGLEDAVNEAKHLGVKVFSVAITPDHLEPRLSIIATDH 207 K ++++TDG HP K P ++ +A+ G+ ++A++ E +L +I+ D Sbjct: 153 VKVVLLMTDGIDHP----KNP--DVQSISEDARISGISFITIALSTVVNEAKLRLISGDS 206 Query: 208 TYRRNFTAADWGQSRDAEEAISQTIDTIVDMIKNNVEQVCCSFECQPARGPPGLRGDPGF 267 + +D +D I D + E+ C C+ +G PG DPG Sbjct: 207 SSEPTLLLSD-----------PTLVDKIQDRLDILFEKKCERKICECEKGDPG---DPGP 252 Query: 268 EGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGI 327 G G PG+ GE+G G+PG +KG GE+G G GYKG+KG+RG Sbjct: 253 PGTHGNPGIKGERGPKGNPGN-------------AQKGEAGERGPGGIPGYKGDKGERGE 299 Query: 328 DGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGS 387 G G+KG+ G PG G KG G GI GPP GDPG G +G KGEPG G G PG+ Sbjct: 300 CGKPGIKGDKGSPGPYGPKGPRGIQGITGPP---GDPGPKGFQGNKGEPGPPGPYGSPGA 356 Query: 388 --------SGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGE--RGPRGTPG 437 G G EG+PG PGP G GE G G GP+G PGERG PGE GP+G G Sbjct: 357 PGIGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKG 415 Query: 438 TRGPRGD--------PGEAGPQGDQGREGPVGVP-----GDPGEAGPIGPKGYRG--DEG 482 + GP G GE G G G +GP+G+P G+ G GPIGP G +G +G Sbjct: 416 SEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQG 475 Query: 483 PPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTKG 541 PGS+G G GP GP G G+ G GP G G+ G PG PG PG GA G G G Sbjct: 476 LPGSKGEVGQMGPTGPRGPVGI----GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAG 531 Query: 542 YPGLKGDEGEAG----DPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 PG +G EG G P D +G +G +G GPEGP+G PG GP G Sbjct: 532 LPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFG 584 Score = 115 bits (287), Expect = 3e-25 Identities = 70/176 (39%), Positives = 85/176 (48%), Gaps = 30/176 (17%) Query: 423 ERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEG 482 E+G PG+ GP PGT G G GE GP+G+ G G+ GE GP G GY+GD+G Sbjct: 243 EKGDPGDPGP---PGTHGNPGIKGERGPKGNPGN----AQKGEAGERGPGGIPGYKGDKG 295 Query: 483 PPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGTKG 541 G G PG+ G++G GP G G G G G PG+ G G G KG Sbjct: 296 ERGE------------CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKG 343 Query: 542 YPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGP-----PGHQGPPGPD 592 PG G G G PG I +G+KG +G G G GP PG GP GP+ Sbjct: 344 EPGPPGPYGSPGAPG-----IGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPE 394 Score = 95.1 bits (235), Expect = 3e-19 Identities = 56/115 (48%), Positives = 67/115 (58%), Gaps = 14/115 (12%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGY--QGMKGEKGSRGEKGS 312 A+G PG+RG PG G RG G G KG+ G G PG GP GY QG+KGE+G +G G Sbjct: 665 AKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGP 723 Query: 313 RGPKGY-----KGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKG 362 +G G+ KGE G+RG G G KGE+G P GSPG G+QGP G G Sbjct: 724 KGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEP------GSPGKQGLQGPKGDLG 772 Score = 80.1 bits (196), Expect = 1e-14 Identities = 48/107 (44%), Positives = 55/107 (51%), Gaps = 20/107 (18%) Query: 487 EGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGN--RGAPGINGTKGYPG 544 E +G PG GPPG G G +GE GP GN PGN +G G G G PG Sbjct: 241 ECEKGDPGDPGPPGTHGNPGIKGERGPKGN-----------PGNAQKGEAGERGPGGIPG 289 Query: 545 LKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 KGD+GE G+ G G+KG KG GP GP+GP G QG GP Sbjct: 290 YKGDKGERGECGKP-------GIKGDKGSPGPYGPKGPRGIQGITGP 329 Score = 63.9 bits (154), Expect = 7e-10 Identities = 52/206 (25%), Positives = 92/206 (44%), Gaps = 19/206 (9%) Query: 780 SQGRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSAS 839 S G+ GL K + L ++ +K +T KC + +P ++ ++D S S Sbjct: 758 SPGKQGLQGPKGDLG-LTKEEIIKLITEICGCGPKCKE--------TPLELVFVIDSSES 808 Query: 840 VGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTA 899 VG NF K F K +A+R T R+ ++ YS + + A+L+ + Sbjct: 809 VGPENFQIIKNFVKTMADRVALDLAT-----ARIGIINYS---HKVEKVANLKQFSSKDD 860 Query: 900 LASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAV 959 AVD M ++ + T AL + +A G KK L+ +DG + + + V Sbjct: 861 FKLAVDNMQYLGEGTYTATALQAANDMFEDARPG-VKKVALVITDGQTDSRDKEKLTEVV 919 Query: 960 QEAQRAGIEIFVVVVGRQVNEPHIRV 985 + A +EIFV+ V ++ N+P+ + Sbjct: 920 KNASDTNVEIFVIGVVKK-NDPNFEI 944 Score = 57.8 bits (138), Expect = 5e-08 Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 9/199 (4%) Query: 829 DITILLDGSASVGSHNFDTTKRFAKRLAERF--LTAGRTDPAHDVRVAVVQYSGTGQQRP 886 DI ++D S S FD K F L+++ LT GR+ +D+++A +Q+S + Q P Sbjct: 48 DIVFIVDSSESSKIALFDKQKDFVDSLSDKIFQLTPGRS-LEYDIKLAALQFSSSVQIDP 106 Query: 887 ERASLQFLQNYTALASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGN 946 +S + LQ + V +M+ I T A+ TR + K +LL +DG Sbjct: 107 PFSSWKDLQTF---KQKVKSMNLIGQGTFSYYAISNATRLLKREGRKDGVKVVLLMTDGI 163 Query: 947 SQGATPAAIEKAVQEAQRAGIEIFVVVVGRQVNEPHIRVLVTGKTAEYDVAYGESHLFRV 1006 P ++ ++A+ +GI + + VNE +R++ ++E + + L V Sbjct: 164 DHPKNP-DVQSISEDARISGISFITIALSTVVNEAKLRLISGDSSSEPTLLLSDPTL--V 220 Query: 1007 PSYQALLRGVFHQTVSRKV 1025 Q L +F + RK+ Sbjct: 221 DKIQDRLDILFEKKCERKI 239 Score = 56.6 bits (135), Expect = 1e-07 Identities = 57/225 (25%), Positives = 98/225 (43%), Gaps = 31/225 (13%) Query: 614 IDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEH 673 ID++F++DSSES + F+ KDFV D LS D++ + PG+S ++ + Q Sbjct: 47 IDIVFIVDSSESSKIALFDKQKDFV----DSLS-DKIFQLTPGRSLEYDIKLAALQFSSS 101 Query: 674 VSLRSP--SIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNN--RIALVITD 729 V + P S +++Q K+ +KS+ + GTF+ A+ L + ++ L++TD Sbjct: 102 VQIDPPFSSWKDLQTFKQKVKSMNLIGQGTFSYYAISNATRLLKREGRKDGVKVVLLMTD 161 Query: 730 G-----RSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRP 784 G D Q + + GI +++ + V + +L +IS S P Sbjct: 162 GIDHPKNPDVQSISEDARI---SGISFITIALSTVVN----EAKLRLIS----GDSSSEP 210 Query: 785 GLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPAD 829 L L + ++D I +KKC C P D Sbjct: 211 TLLLSDPTLVDKIQDRL------DILFEKKCERKICECEKGDPGD 249 Score = 56.2 bits (134), Expect = 2e-07 Identities = 50/187 (26%), Positives = 86/187 (45%), Gaps = 26/187 (13%) Query: 32 QDCPVDLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLRDRYYRCDRNLVWNAGAL 91 ++ P++L FV+D+SESV P + +K+F K D + G + Sbjct: 793 KETPLELVFVIDSSESVG----PENFQI--IKNFVKTMADRVALDLATA------RIGII 840 Query: 92 HYSDEVEIIQGLTRMPGGRDALKSSVDAVKYFGKGTYTDCAIKKGLEQLLVGGSHLKENK 151 +YS +VE + L + +D K +VD ++Y G+GTYT A++ + +K K Sbjct: 841 NYSHKVEKVANLKQF-SSKDDFKLAVDNMQYLGEGTYTATALQAANDMFEDARPGVK--K 897 Query: 152 YLIVVTDGHPLEGYKEPCGGLEDAVNEAKHLGVKVFSVAITPDH------LEPRLSIIAT 205 +V+TDG KE L + V A V++F + + + +++IAT Sbjct: 898 VALVITDGQTDSRDKEK---LTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIAT 954 Query: 206 D--HTYR 210 D H Y+ Sbjct: 955 DPEHVYQ 961 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 312 bits (800), Expect = 9e-85 Identities = 182/379 (48%), Positives = 196/379 (51%), Gaps = 50/379 (13%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RGPPGL G PG G G PG G KG AG PG PG G G QGM GE RG GS GP Sbjct: 683 RGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGE---RGGLGSPGP 739 Query: 316 KGYKGEKGKRGIDGVDGV---------------------KGEMGYPGLPGC---KGSPGF 351 KG KGE G G DGV G KGE G PGLPG +GSPG Sbjct: 740 KGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGE 799 Query: 352 DGIQGPPGPKGDPGAFGL------KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGE 405 G GPPGP G PGA G KGE+G PG GE G PG +GP G G G PGP G Sbjct: 800 RGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGV 859 Query: 406 KGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGD 465 KGE G G PG G PG RG PG G G PG GP G PG+ GP G G G PG Sbjct: 860 KGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGN---TGAPGS 916 Query: 466 PGEAGPIGPKGYRGDEGPPGSEGARGAPGP---------AGPPGDPGLMGERGEDGPAG- 515 PG +GP G G G++G PG++G GAPGP G G PG+ G RG GP G Sbjct: 917 PGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGV 976 Query: 516 NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDD---NNDIAPRGVKGAKG 572 G G PG G G RG PG G G G G+ G G+PG D D +P G KG +G Sbjct: 977 KGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGG-KGDRG 1035 Query: 573 YRGPEGPQGPPGHQGPPGP 591 G G G PGH GPPGP Sbjct: 1036 ENGSPGAPGAPGHPGPPGP 1054 Score = 304 bits (778), Expect = 3e-82 Identities = 173/385 (44%), Positives = 195/385 (50%), Gaps = 50/385 (12%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GPPG G PG +GE G PGLPG G G PG G+ GP G G G G GE G +G + Sbjct: 768 GPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGER 827 Query: 317 GYKGEKGKRGIDGV---------------DGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361 G GEKG+ G GV GVKGE G PG PG G PG G+ GPPG Sbjct: 828 GAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSN 887 Query: 362 GDPGAFGLKGEKGEPGADGEAGR------PGSSGPSGDEGQPGEPGPPGEKGEAG----- 410 G+PG G G G+ G G AG PG SGP GD GQPGE G PG +G G Sbjct: 888 GNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPL 947 Query: 411 -------------------DEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQ 451 G+PGP G GE G PG G G G GP+G PG AG Sbjct: 948 GIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTA 1007 Query: 452 GDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGED 511 G+ GR+G G G PG G G KG RG+ G PG+ GA G PGP GP G G G+RGE Sbjct: 1008 GEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGES 1067 Query: 512 GPAG----NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGV 567 GPAG G G G PG G RG G G +G G+KG G G+PG + P G Sbjct: 1068 GPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSP-GPAGQ 1126 Query: 568 KGAKGYRGPEGPQGPPGHQGPPGPD 592 +GA G GP GP+GP G GPPG D Sbjct: 1127 QGAIGSPGPAGPRGPVGPSGPPGKD 1151 Score = 302 bits (774), Expect = 9e-82 Identities = 168/362 (46%), Positives = 191/362 (52%), Gaps = 41/362 (11%) Query: 257 GPPGLRGDPGFEGE---RGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSR 313 GPPG G PG G +G PG PG+ G +G PG PG +GP G G GE G G G R Sbjct: 183 GPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGER 242 Query: 314 G---PKGYKGE---------KGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361 G P G KG KG RG DG +G KGE G PGL G G PG +G GP GP+ Sbjct: 243 GLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPR 302 Query: 362 GDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGE---------KGEAGDE 412 G PG E+G PG G AG G+ G G +GQPG PGPPG KGE G Sbjct: 303 GAPG------ERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPA 356 Query: 413 GNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPI 472 G+PG +GAPG+RG PG P+G G +GP G PG G G +G GP G+PG PG G Sbjct: 357 GSPGSNGAPGQRGEPG---PQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGAR 413 Query: 473 GPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDG----PAGNGTEGFPGFPGYP 528 GP G G G PG G G PG G G+PG GERGE G P G +G G PG P Sbjct: 414 GPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEP 473 Query: 529 GNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGP 588 G G PG G +G PG +G G G PG+ P G +GA G GP G G PG G Sbjct: 474 GANGLPGAAGERGAPGFRGPAGPNGIPGEK----GPAGERGAPGPAGPRGAAGEPGRDGV 529 Query: 589 PG 590 PG Sbjct: 530 PG 531 Score = 299 bits (765), Expect = 1e-80 Identities = 173/367 (47%), Positives = 198/367 (53%), Gaps = 41/367 (11%) Query: 255 ARGPPGLRG---DPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG 311 A G PGLRG +PG G +G+PG GE+GEAG PG PG G G G GE G+ G G Sbjct: 421 ANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPG 480 Query: 312 SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKG 371 + G +G G +G G +G+ G KG G G PG G G G PG G PG G++G Sbjct: 481 AAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRG---AAGEPGRDGVPGGPGMRG 537 Query: 372 EKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGP---DGAP---GERG 425 G PG G G+PG G G+ G+PG PGP G +G+ G G PGP DGAP GERG Sbjct: 538 MPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERG 597 Query: 426 GPGERGPRGTPGTR---GPRGDPGEAGPQGDQGREGPV------------GVPGDPGEAG 470 GPG GP+G PG GP+G PG GP GD+G GP G PG+ G+ G Sbjct: 598 GPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPG 657 Query: 471 PIGPKGYRGDEGPPGSEGARGAPGPAGPP---GDPGLMGERGEDGPAGN----GTEGFPG 523 GPKG G G PG +G GAPG GPP G PGL G G GP G G G PG Sbjct: 658 EPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPG 717 Query: 524 FPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPP 583 G PG +G PG G G PG KGD+GE G PG D GV G G RGP GP GPP Sbjct: 718 AAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGAD-------GVPGKDGPRGPTGPIGPP 770 Query: 584 GHQGPPG 590 G G PG Sbjct: 771 GPAGQPG 777 Score = 298 bits (762), Expect = 2e-80 Identities = 171/354 (48%), Positives = 193/354 (54%), Gaps = 25/354 (7%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPG---DLGPVGYQGMKGEKGSRGEKGSR 313 G G RG+ G G G+PG PG G AG PG PG ++GP G G G G RGE G + Sbjct: 315 GAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQ 374 Query: 314 GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373 G G +G G GI+G G KGEMG G+PG +PG G +GPPGP G GA GL+G Sbjct: 375 GHAGAQGPPGPPGINGSPGGKGEMGPAGIPG---APGLMGARGPPGPAGANGAPGLRGGA 431 Query: 374 GEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPG---ERGGPGER 430 GEPG +G G PG G G+ G PG PG GE G+ G G PG +G PG ERG PG R Sbjct: 432 GEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFR 491 Query: 431 ---GPRGTPGTRGP---RGDPGEAGPQGDQGREGPVGVPGDPGEAG----PIGPKGYRGD 480 GP G PG +GP RG PG AGP+G G G GVPG PG G P GP G G Sbjct: 492 GPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGP-GSDGK 550 Query: 481 EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN----GTEGFPGFPGYPGNRGAPGI 536 GPPGS+G G PGP GP G G G G GP GN G G G PG PG +G PG Sbjct: 551 PGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGK 610 Query: 537 NGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 NG G G G G GD G D P+G++G G GP G G PG GP G Sbjct: 611 NGETGPQGPPGPTGPGGDKG-DTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKG 663 Score = 298 bits (762), Expect = 2e-80 Identities = 165/372 (44%), Positives = 197/372 (52%), Gaps = 39/372 (10%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GPPG+ G PG +GE G G+PG G G G PG G G G++G G G+ G++G Sbjct: 384 GPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEP 443 Query: 317 GYKGEKGKRGIDGVDGVKGE------------MGYPGLPGCKGSPGF---------DGIQ 355 G +GE+G+ GI GV G KGE G PG G +G+PGF G + Sbjct: 444 GPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEK 503 Query: 356 GPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPG---EPGPPGEKGEAGDE 412 GP G +G PG G +G GEPG DG G PG G G G PG +PGPPG +GE+G Sbjct: 504 GPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRP 563 Query: 413 GNPGPDGA---PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEA 469 G PGP G PG G PG +G G PG G RG PG GPQG G+ G G G PG Sbjct: 564 GPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPG-- 621 Query: 470 GPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDG-------PAGNGTEGFP 522 P GP G +GD GPPG +G +G PG GPPG+ G GE G G P G G G P Sbjct: 622 -PTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAP 680 Query: 523 GFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAP--RGVKGAKGYRGPEGPQ 580 G G PG GAPG+ G G PG +G +G AG PG P +G+ G +G G GP+ Sbjct: 681 GERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPK 740 Query: 581 GPPGHQGPPGPD 592 G G G PG D Sbjct: 741 GDKGEPGGPGAD 752 Score = 298 bits (762), Expect = 2e-80 Identities = 169/354 (47%), Positives = 193/354 (54%), Gaps = 23/354 (6%) Query: 257 GPPGLRGD---PGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSR 313 GP G +GD PG +G +G PG G GE G PG PG G G G G KG G G R Sbjct: 624 GPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGER 683 Query: 314 GPKGYKGEKGKRG---IDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370 GP G G G RG G +G KG G PG PG G+PG G+ G G G PG G K Sbjct: 684 GPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDK 743 Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP---GPDGAPGERGGP 427 GE G PGADG G+ G GP+G G PG G PG+KGE G G P GP G+PGERG Sbjct: 744 GEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGET 803 Query: 428 GERGPRGTPGTRGPRGDP---GEAGPQGDQGREGPVGV---PGDPGEAGPIGPKGYRGDE 481 G GP G PG G G+P GE G G++G GP GV PG G AGP GP+G +G+ Sbjct: 804 GPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGER 863 Query: 482 GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTK 540 G PG GA G PG G PG PG G G GP+G+ G +G PG G G G+PG++G K Sbjct: 864 GSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPK 923 Query: 541 ---GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G PG KG G G PG P G+ G G RG GP G PG +G PGP Sbjct: 924 GDAGQPGEKGSPGAQGPPGAP----GPLGIAGITGARGLAGPPGMPGPRGSPGP 973 Score = 295 bits (754), Expect = 2e-79 Identities = 178/399 (44%), Positives = 196/399 (49%), Gaps = 68/399 (17%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G G G PG GERG PG PG KG AG PG PG G G+ G GEKG G G +G Sbjct: 228 GKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGEN 287 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376 G GE G G G G GE G PGLPG G+ G DG +G G G PG G G G P Sbjct: 288 GLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSP 347 Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGP------------------PGEKGEAGDEGNPGPD 418 GA GE G GS G +G GQ GEPGP PG KGE G G PG Sbjct: 348 GAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAP 407 Query: 419 GAPGERGGPGERGPRGTPGTRGPRGDP------GEAGPQGDQGREGPVGVPGDPGEAGPI 472 G G RG PG G G PG RG G+P GE GP+G++G G GVPG GE G Sbjct: 408 GLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKD 467 Query: 473 GPKGYRGDEGPPGSEGARGAP---GPAGP---PGDPGLMGERGEDGPAG----------N 516 G G G G PG+ G RGAP GPAGP PG+ G GERG GPAG + Sbjct: 468 GSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRD 527 Query: 517 GTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGP 576 G G PG G PG+ G PG +G G PG +G+ G G PG PRG G G+ GP Sbjct: 528 GVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPS----GPRGQPGVMGFPGP 583 Query: 577 E------------------GPQGPPGH------QGPPGP 591 + GPQGPPG QGPPGP Sbjct: 584 KGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGP 622 Score = 292 bits (747), Expect = 1e-78 Identities = 162/345 (46%), Positives = 184/345 (53%), Gaps = 22/345 (6%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GP G G PG G G PG PG G G PG PG GP G G G G G G G Sbjct: 174 GPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGES 233 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376 G G G+RG+ G G+KG G PG PG KG GFDG G KG+ GA GLKGE G P Sbjct: 234 GRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGE---KGETGAPGLKGENGLP 290 Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGE---AGDEGNPGPDGAPGERGGP------ 427 G +G G G G G+ G+PG PG G +G G +G PGP G PG G P Sbjct: 291 GENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAK 350 Query: 428 GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487 GE GP G+PG+ G G GE GPQG G +GP G PG G G G G G G PG Sbjct: 351 GEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLM 410 Query: 488 GARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKG 547 GARG PGPAG G PGL G GE P NG +G PG G G G PG+ PG KG Sbjct: 411 GARGPPGPAGANGAPGLRGGAGE--PGKNGAKGEPGPRGERGEAGIPGV------PGAKG 462 Query: 548 DEGEAGDPGDDNNDIAP--RGVKGAKGYRGPEGPQGPPGHQGPPG 590 ++G+ G PG+ + P G +GA G+RGP GP G PG +GP G Sbjct: 463 EDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAG 507 Score = 292 bits (747), Expect = 1e-78 Identities = 168/374 (44%), Positives = 193/374 (51%), Gaps = 39/374 (10%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G G RG PGF G G G+PGEKG AG+ G PG GP G G G G G G RG Sbjct: 480 GAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMP 539 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376 G G G G G G +GE G PG PG G G G+ G PGPKG+ GA G GE+G P Sbjct: 540 GSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGP 599 Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD------EGNPGPDGAPGERGGPGER 430 G G G PG +G +G +G PG GP G+KG+ G +G PG G PGE G PGE Sbjct: 600 GGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEP 659 Query: 431 GPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGAR 490 GP+G G G G G+AG G++G G G PG G AGP GP+G +G GPPG GA Sbjct: 660 GPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAA 719 Query: 491 GAPGPAGPPGD------PGLMGERGE------------DGPAG-NGTEGFPGFPGYPGNR 531 G PG G PG+ PG G++GE DGP G G G PG G PG++ Sbjct: 720 GTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDK 779 Query: 532 ---GAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAP-----------RGVKGAKGYRGPE 577 GAPG+ G G G G+ GE G PG AP RG G KG GP Sbjct: 780 GEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPP 839 Query: 578 GPQGPPGHQGPPGP 591 G GPPG GP GP Sbjct: 840 GVAGPPGGSGPAGP 853 Score = 290 bits (743), Expect = 4e-78 Identities = 181/412 (43%), Positives = 205/412 (49%), Gaps = 78/412 (18%) Query: 257 GPPGLRG---DPGFEGERGKPGLPGEKGEAGDPGRPGDLGP------VGYQGMKGEKGSR 307 G PG+RG PG G GKPG PG +GE+G PG PG GP +G+ G KG G+ Sbjct: 531 GGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAP 590 Query: 308 GEKGSRG---------PKGYKGEKGKRGIDGVDGV---KGEMGYPG------LPGCKGSP 349 G+ G RG P G GE G +G G G KG+ G PG LPG G P Sbjct: 591 GKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPP 650 Query: 350 GFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEA 409 G +G G PGPKGD GA G G KG+ GA GE G PG +G G G G PGP G KG A Sbjct: 651 GENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAA 710 Query: 410 GDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDP------------GEAGPQGDQGRE 457 G G PG G PG +G PGERG G+PG +G +G+P G GP G G Sbjct: 711 GPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPP 770 Query: 458 GPVGVPGD---------PGEAGPIGPKGYRGDEGP---------------PGSEGARGAP 493 GP G PGD PG AGP G G RG+ GP PG +G RGAP Sbjct: 771 GPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAP 830 Query: 494 GPAGPPGDPGLMGERGEDGPAG----------NGTEGFPGFPGYPGNR---GAPGINGTK 540 G G G PG+ G G GPAG G+ G PG G+PG R G PG NG Sbjct: 831 GEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNP 890 Query: 541 GYPGLKGDEGEAGDPGDDNNDIAP--RGVKGAKGYRGPEGPQGPPGHQGPPG 590 G PG G G+ G PG N AP GV G KG G G +G PG QGPPG Sbjct: 891 GPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPG 942 Score = 289 bits (740), Expect = 8e-78 Identities = 166/362 (45%), Positives = 188/362 (51%), Gaps = 36/362 (9%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GPPG+ G PG G G PG G KGE G PG PG G G +G+ G GS G G GP Sbjct: 837 GPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPS 896 Query: 317 GYKGEKG------KRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP---------- 360 G G+ G G G GV G G G PG KGSPG G G PGP Sbjct: 897 GSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGAR 956 Query: 361 --KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD---EGNP 415 G PG G +G G G GE+G+PG++G SG+ G PG G PG G AG+ +GNP Sbjct: 957 GLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNP 1016 Query: 416 GPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475 G DG PG G PG +G RG G+ G G PG GP G GP G GD GE+GP GP Sbjct: 1017 GSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGP---VGPAGKSGDRGESGPAGP- 1072 Query: 476 GYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAP 534 G PG G+RGAPGP GP GD G GERG G G+ G G PG PG PG G Sbjct: 1073 -----AGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQ 1127 Query: 535 GINGTKGYPGLKGDEGEAGDPGDDNND-----IAPRGVKGAKGYRGPEGPQGPPGHQGPP 589 G G+ G G +G G +G PG D I P G +G +G RG EG G PG GPP Sbjct: 1128 GAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPP 1187 Query: 590 GP 591 GP Sbjct: 1188 GP 1189 Score = 286 bits (731), Expect = 9e-77 Identities = 170/373 (45%), Positives = 190/373 (50%), Gaps = 39/373 (10%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G PGL+G+ G GE G PG G +G G+ GRPG G G +G G +GS G+ G GP Sbjct: 279 GAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPP 338 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPG---FDGIQGPP--------------- 358 G G G G G G G G G PG +G PG G QGPP Sbjct: 339 GTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEM 398 Query: 359 GPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQ---PGEPGPPGEKGEAGDEGNP 415 GP G PGA GL G +G PG G G PG G +G+ G+ GEPGP GE+GEAG G P Sbjct: 399 GPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVP 458 Query: 416 GPDGAPGERGGPGERGPRGTPGTRGPRGDP---GEAGPQGDQGREGPVGVPGDPGEAGPI 472 G G G+ G PGE G G PG G RG P G AGP G G +GP G G PG AGP Sbjct: 459 GAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPR 518 Query: 473 GPKGYRGDEGPPGSEGARGAPG-PAGP-----PGDPGLMGERGEDGPAG----NGTEGFP 522 G G G +G PG G RG PG P GP PG PG GE G GP G G G Sbjct: 519 GAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVM 578 Query: 523 GFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN-----NDIAPRGVKGAKGYRGPE 577 GFPG GN GAPG NG +G PG G +G G G+ P G KG G GP+ Sbjct: 579 GFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQ 638 Query: 578 GPQGPPGHQGPPG 590 G QG PG GPPG Sbjct: 639 GLQGLPGTGGPPG 651 Score = 283 bits (725), Expect = 4e-76 Identities = 165/365 (45%), Positives = 188/365 (51%), Gaps = 35/365 (9%) Query: 257 GPPGLRG---DPGFEGERGKPGLPGEKGEAGDPGRPGD------------LGPVGYQGMK 301 GPPG G +PG +G+ G PG PG KG+AG PG G GP G +G K Sbjct: 648 GPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGK 707 Query: 302 GEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361 G G G G+ G G +G G+RG G G KG+ G PG PG G PG DG +GP GP Sbjct: 708 GAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPI 767 Query: 362 GDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAP 421 G PG G G+KGE GA G PG +GP G G+ GE GPPG G G G G G Sbjct: 768 GPPGPAGQPGDKGEGGAPG---LPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGK 824 Query: 422 GERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAG-------PIGP 474 GERG PGE+G G PG GP G G AGP G QG +G G PG PG AG P GP Sbjct: 825 GERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLP-GP 883 Query: 475 KGYRGDEGPPGSEGARGAPGPAGP------PGDPGLMGERGEDG-PAGNGTEGFPGFPGY 527 G G+ GPPG G+ G GP GP PG PG+ G +G+ G P G+ G G PG Sbjct: 884 PGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGA 943 Query: 528 PGNRGAPGINGTKGYPGLKGDEGEAGDPGDD--NNDIAPRGVKGAKGYRGPEGPQGPPGH 585 PG G GI G +G G G G G PG + G G G RGP GPQG PG Sbjct: 944 PGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGL 1003 Query: 586 QGPPG 590 G G Sbjct: 1004 AGTAG 1008 Score = 271 bits (694), Expect = 2e-72 Identities = 149/333 (44%), Positives = 177/333 (53%), Gaps = 20/333 (6%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GPPG G+PG G G PG G G AG+ G PG G G KG+ G GEKGS G + Sbjct: 882 GPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGS---PGVSGPKGDAGQPGEKGSPGAQ 938 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376 G G G GI G+ G +G G PG+PG +GSPG G++ G G PGA GL GE+G P Sbjct: 939 GPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVK---GESGKPGANGLSGERGPP 995 Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436 G G G G++G G +G PG G PG G G +G+ G +G+PG G PG GP G Sbjct: 996 GPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPV 1055 Query: 437 GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPA 496 G G GD GE+GP G G GP G G PG GP G KG G+ G G +G RG PG Sbjct: 1056 GPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNP 1115 Query: 497 GPPGDPGLMGERGEDG-PAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDP 555 G PG PG G++G G P G G G G PG G G G G PG +G+ GE Sbjct: 1116 GAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGE---- 1171 Query: 556 GDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGP 588 RG +G+ G+ G GP GPPG GP Sbjct: 1172 ---------RGSEGSPGHPGQPGPPGPPGAPGP 1195 Score = 260 bits (665), Expect = 4e-69 Identities = 138/316 (43%), Positives = 161/316 (50%), Gaps = 14/316 (4%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G G G PG G +G G PGEKG G G PG GP+G G+ G +G G G GP+ Sbjct: 909 GNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPR 968 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376 G G +G +G G G G G G PG +G PG G G PG G+PG+ GL G G P Sbjct: 969 GSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSP 1028 Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436 G G+ G GS G G G PG PGP G G++GD G GP G G PG G RG P Sbjct: 1029 GGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGP---AGPAGAPGPAGSRGAP 1085 Query: 437 GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPA 496 G +GPRGD GE G +G G +G G PG+PG G GP G +G G PG G RG GP+ Sbjct: 1086 GPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPS 1145 Query: 497 GPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPG 556 GPPG G G G GP PG GNRG G G+ G+PG G G G PG Sbjct: 1146 GPPGKDGTSGHPGPIGP-----------PGPRGNRGERGSEGSPGHPGQPGPPGPPGAPG 1194 Query: 557 DDNNDIAPRGVKGAKG 572 + + G G Sbjct: 1195 PCCGGVGAAAIAGIGG 1210 Score = 227 bits (579), Expect = 4e-59 Identities = 130/278 (46%), Positives = 145/278 (52%), Gaps = 13/278 (4%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGR---PGDLGPVGYQGMKGEKGSRGEKGSR 313 G GL G PG G RG PG G KGE+G PG G+ GP G QG+ G G+ GE G Sbjct: 954 GARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRD 1013 Query: 314 GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373 G G G G+ G G G +GE G PG PG G PG G GP G GD G G G Sbjct: 1014 GNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPA 1073 Query: 374 GEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPR 433 G PG G G PG GP GD+G+ GE G G KG G GNP GAPG G G++G Sbjct: 1074 GAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNP---GAPGSPGPAGQQGAI 1130 Query: 434 GTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAP 493 G+PG GPRG G +GP G G G PG GP GP+G RG+ G GS G G P Sbjct: 1131 GSPGPAGPRGPVGPSGPPGKD------GTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQP 1184 Query: 494 GPAGPPGDPG-LMGERGEDGPAGNGTEGFPGFPGYPGN 530 GP GPPG PG G G AG G E GF Y G+ Sbjct: 1185 GPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYYGD 1222 Score = 191 bits (486), Expect = 2e-48 Identities = 115/259 (44%), Positives = 126/259 (48%), Gaps = 38/259 (14%) Query: 355 QGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPG--EKGEAGDE 412 QGP GPKGDPG G+ G G+PG G+ G PGS PGPPG E G + Sbjct: 102 QGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGS------------PGPPGICESCPTGPQ 149 Query: 413 GNP---------------GPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGRE 457 G G PG G PG GP GT G G G PG GP G+ G+ Sbjct: 150 NYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQA 209 Query: 458 GPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAP------GPAGPPGDPGLMGERGED 511 GP G PG PG GP GP G G+ G PG G RG P GPAG PG PG+ G RG D Sbjct: 210 GPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFD 269 Query: 512 GPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAK 571 G NG +G G PG G G PG NG G G +G GE G PG RG GA+ Sbjct: 270 G--RNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLP-GAAGARGNDGAR 326 Query: 572 GYRGPEGPQGPPGHQGPPG 590 G G GP GPPG G PG Sbjct: 327 GSDGQPGPPGPPGTAGFPG 345 Score = 176 bits (445), Expect = 1e-43 Identities = 105/240 (43%), Positives = 119/240 (49%), Gaps = 22/240 (9%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RGPPG +G PG G G+PG G G G PGR G G G +G G G+ G G GP Sbjct: 992 RGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGP 1051 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE--- 372 G G GK G G G G G PG G +G+PG P GP+GD G G +G Sbjct: 1052 PGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPG------PQGPRGDKGETGERGAAGI 1105 Query: 373 KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA---PGERGGPGE 429 KG G G G PGS GP+G +G G PGP G +G G G PG DG PG G PG Sbjct: 1106 KGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGP 1165 Query: 430 RGPRGTPGTRGPRGDPGEAGPQGDQGREGP-------VGVPGDPGE-AGPIGPKGYRGDE 481 RG RG G+ G G PG+ GP G G GP + G GE AG P Y GDE Sbjct: 1166 RGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAP--YYGDE 1223 Score = 132 bits (333), Expect = 1e-30 Identities = 92/263 (34%), Positives = 107/263 (40%), Gaps = 68/263 (25%) Query: 397 PGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGR 456 P P GE + P P +G G +G G PG G GDPG G G G Sbjct: 75 PNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGS 134 Query: 457 EGPVGV--------------------------------PGDPGEAGPIGPKGYRGDEGPP 484 GP G+ PG G GP GP G G G P Sbjct: 135 PGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSP 194 Query: 485 GSEGARGAP------GPAGPPGDPGLM------------------GERGEDGPAG-NGTE 519 GS G +G P GP+GPPG PG + GERG GP G G Sbjct: 195 GSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPA 254 Query: 520 GFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN--NDIAPR---------GVK 568 G PGFPG G+RG G NG KG G G +GE G PG++ + PR G+ Sbjct: 255 GIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLP 314 Query: 569 GAKGYRGPEGPQGPPGHQGPPGP 591 GA G RG +G +G G GPPGP Sbjct: 315 GAAGARGNDGARGSDGQPGPPGP 337 Score = 105 bits (263), Expect = 2e-22 Identities = 64/142 (45%), Positives = 71/142 (50%), Gaps = 4/142 (2%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314 A GP G RGD G GERG G+ G +G G+PG PG GP G QG G G G +G G Sbjct: 1084 APGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVG 1143 Query: 315 PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPG-AFGLKGEK 373 P G G+ G G G G G G G G +GSPG G GPPGP G PG G G Sbjct: 1144 PSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAA 1203 Query: 374 GEPGADGEAGRPGSSGP-SGDE 394 G GE + G P GDE Sbjct: 1204 AIAGIGGE--KAGGFAPYYGDE 1223 Score = 52.8 bits (125), Expect = 2e-06 Identities = 40/110 (36%), Positives = 46/110 (41%), Gaps = 25/110 (22%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312 Q A G PG G G G G PG G G PG +GP G +G+RGE+GS Sbjct: 1127 QGAIGSPGPAGPRGPVGPSGPPGKDGTS------GHPGPIGP------PGPRGNRGERGS 1174 Query: 313 RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPG-CKGSPGFDGIQGPPGPK 361 G G+ G+ G G PG PG C G G I G G K Sbjct: 1175 EGSPGHPGQ------------PGPPGPPGAPGPCCGGVGAAAIAGIGGEK 1212 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 311 bits (797), Expect = 2e-84 Identities = 178/378 (47%), Positives = 202/378 (53%), Gaps = 44/378 (11%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGM------KGEKGSRGEK 310 G PG G G G RG+ GL G+KG+ G G PG GPVG QG+ KGE G G+ Sbjct: 1189 GQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQM 1248 Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370 G GP G +G G G DG G G +G PG G KG PG G G PG G PG G + Sbjct: 1249 GPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGER 1308 Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQ---------PGEPGPPGEKGEAGDEGNP---GPD 418 GEKGE G G AG PG GP GD+G PG+PGPPGE G AG +G P G D Sbjct: 1309 GEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDD 1368 Query: 419 GAPGERGGP---GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475 G PG+ G P GE GP G PG RGP G G G QG++G +G G+ G PG+ GPIGP+ Sbjct: 1369 GEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQ 1428 Query: 476 GYRGDEGP---------------PGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN---- 516 G G GP PGS G G PGP GPPG PGL G+ G G G+ Sbjct: 1429 GAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLI 1488 Query: 517 GTEGFPGFPGYPGNRGAP---GINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573 G G PG G G+RG P G +G KG G+ G G G PG P G KGAKG Sbjct: 1489 GLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLP-GPPGPKGAKGS 1547 Query: 574 RGPEGPQGPPGHQGPPGP 591 GP GP+G GH GPPGP Sbjct: 1548 SGPTGPKGEAGHPGPPGP 1565 Score = 305 bits (781), Expect = 1e-82 Identities = 167/346 (48%), Positives = 190/346 (54%), Gaps = 15/346 (4%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G PGL G PG +G G PG G GE G G PG GP+GY G +G KG+ G +G +G K Sbjct: 748 GKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTK 807 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376 G KGE G G G G+KG+ G G PG +G G +G +G GP GDPG G GEKG+ Sbjct: 808 GEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKL 867 Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436 G G G PG GP G G PG PG GEKG G G PGP G G G GERGPRG Sbjct: 868 GVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGIT 927 Query: 437 GTRGPRGD---PGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAP 493 G GP+G+ G AGP G++G GP G G PG GP GP G G G PG G G Sbjct: 928 GKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 987 Query: 494 GPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEA 552 G GPPG PG++G +G G G G G PG PG PG +G PG+ G + G KGD G A Sbjct: 988 GKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKE---GTKGDPGPA 1044 Query: 553 GDPGDDN--------NDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G PG D D G GA G +G EGP GPPG G PG Sbjct: 1045 GLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPG 1090 Score = 298 bits (764), Expect = 1e-80 Identities = 170/382 (44%), Positives = 201/382 (52%), Gaps = 45/382 (11%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP---VGYQGMKGEKGSRGE 309 Q G PG +G PG G+ G PG PG++GE G G+ G GP VG QG GE G GE Sbjct: 954 QGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGE 1013 Query: 310 KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGL 369 +G GP G GE+G G+ G +G KG+ G GLPG G PG G G G G GA GL Sbjct: 1014 RGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGL 1073 Query: 370 KGEKGEPGADGEAGRPGSSGPSGDEGQ---PGEPGPPGEKGEAGDEGNPGPDGAPGERGG 426 KG +G PG G AG PG GP+G G PG PGP G G AG++G PG G G G Sbjct: 1074 KGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR 1133 Query: 427 PGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGS 486 G +GP G PG GP G PGE G +G+ G G G GD GE GP GP G +G G PG Sbjct: 1134 DGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGP 1193 Query: 487 EGARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFPGYPGNR----------- 531 GA G PGP G GL G++G++GP G G G G PG PG + Sbjct: 1194 SGADGEPGPRG---QQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGP 1250 Query: 532 ----------GAPGINGTKGYP---------GLKGDEGEAGDPG--DDNNDIAPRGVKGA 570 GAPG +G +G P G KG+ GEAG+PG + P+G +G Sbjct: 1251 PGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGE 1310 Query: 571 KGYRGPEGPQGPPGHQGPPGPD 592 KG GP G GPPG +GPPG D Sbjct: 1311 KGESGPSGAAGPPGPKGPPGDD 1332 Score = 292 bits (748), Expect = 1e-78 Identities = 160/347 (46%), Positives = 185/347 (53%), Gaps = 20/347 (5%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314 ARG PG G G G G GLPGEKG GDPG G GP G+ G RG+ G G Sbjct: 617 ARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGP------PGDDGERGDDGEVG 670 Query: 315 PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKG 374 P+G GE G RG+ G G G G PG+ G G PG G GP G G PG G G +G Sbjct: 671 PRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQG 730 Query: 375 EPGADGEAGRPGSSGPSGDEGQP------GEPGPPGEKGEAGDEGNPGPDGAPGERGGPG 428 PG G G PG GP G G P G PG PG++G G++G GP G G G PG Sbjct: 731 LPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPG 790 Query: 429 ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEG 488 RG +G G RG +G GE G G G +G +G+ GD GE GP GP+G G EGP G G Sbjct: 791 PRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGG 850 Query: 489 ARGAPGPAGPPGDPGLMGERGEDG-PAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKG 547 G PGP GPPG+ G +G G G P G +G GFPG+PG G G GT G PG +G Sbjct: 851 PNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRG 910 Query: 548 DEGEAGDPGDDNNDIAPRGV---KGAKGYRGPEGPQGPPGHQGPPGP 591 G G G+ PRG+ G KG G +GP GPPG +GP GP Sbjct: 911 QRGPTGPRGER----GPRGITGKPGPKGNSGGDGPAGPPGERGPNGP 953 Score = 292 bits (748), Expect = 1e-78 Identities = 163/356 (45%), Positives = 182/356 (51%), Gaps = 25/356 (7%) Query: 256 RGPPGLRGDPGFEGERGKPG------------LPGEKGEAGDPGRPGDLGPVGYQGMKGE 303 +GPPG G+ G GE+G G LPG G G PG GD G +G G KG Sbjct: 1110 QGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGS 1169 Query: 304 KGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD 363 KG +GE+G GP G +G G+ G G DG G G GL G KG G G GPPGP G Sbjct: 1170 KGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGL 1229 Query: 364 PGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGE 423 G G GEKGE G G+ G PG GP G G PG GP G G G+ G G G PGE Sbjct: 1230 QGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGE 1289 Query: 424 RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGP 483 G PG G G PG +G RG+ GE+GP G G GP G PGD G G GP G+ GD GP Sbjct: 1290 AGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGP 1349 Query: 484 PGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYP 543 PG G G GP G GD G G+ G GP G PG G PG RG PG G +G Sbjct: 1350 PGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGE-----PGPSGPPGKRGPPGPAGPEGRQ 1404 Query: 544 GLKGDEGEAG--DPGDDNNDIAPRGV------KGAKGYRGPEGPQGPPGHQGPPGP 591 G KG +GEAG P I P+G G +G GP G QG PG GP GP Sbjct: 1405 GEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGP 1460 Score = 290 bits (741), Expect = 6e-78 Identities = 169/380 (44%), Positives = 189/380 (49%), Gaps = 48/380 (12%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GPPGLRG PG G G G G KG G PG PG G G +G G G G G GP+ Sbjct: 1051 GPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQ 1110 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376 G G G++G G G +G G GL G G PG G GPPG GD G G G+KG Sbjct: 1111 GPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSK 1170 Query: 377 GADGEAGRPGSSGPSGDEGQPG------EPGPPGEKG---EAGDEGN------------- 414 G GE G PG +GP G GQPG EPGP G++G + GDEG Sbjct: 1171 GDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQ 1230 Query: 415 --PGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQ------------GDQGREGPV 460 PGP G GE G G+ GP G PG RGP G PG GPQ G++G G Sbjct: 1231 GLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEA 1290 Query: 461 GVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTE 519 G PG PGE GP GPKG RG++G G GA G PGP GPPGD G +G GP G G Sbjct: 1291 GEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDD---GPKGSPGPVGFPGDP 1347 Query: 520 GFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN--------NDIAPRGVKGAK 571 G PG PG G G PG G G PG G G G+PG P G +G K Sbjct: 1348 GPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEK 1407 Query: 572 GYRGPEGPQGPPGHQGPPGP 591 G +G G +GPPG GP GP Sbjct: 1408 GAKGEAGLEGPPGKTGPIGP 1427 Score = 288 bits (738), Expect = 1e-77 Identities = 168/368 (45%), Positives = 198/368 (53%), Gaps = 39/368 (10%) Query: 257 GPPGLRGDPGFEGERGKPGL---------PGEKGEAGDPGRPG---------DLGPVGYQ 298 GPPG RG+ G EG +G+ G PGEKG+ G PG PG +G G+ Sbjct: 832 GPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFP 891 Query: 299 GMKGEKGSRGE------KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFD 352 G GEKG RG +G RGP G +GE+G RGI G G KG G G G G G + Sbjct: 892 GANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPN 951 Query: 353 GIQGP---PGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEA 409 G QGP PGPKG PG G G G PG GE G G +GP G G G GP GE G Sbjct: 952 GPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPM 1011 Query: 410 GDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEA 469 G+ G+PGP G PGE+G PG G GT G GP G PG+ GP G + G PGD G Sbjct: 1012 GERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLR------GFPGDRGLP 1065 Query: 470 GPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYP 528 GP+G G +G+EGPPG G G+PG GP G G +G G GP G G G G PG Sbjct: 1066 GPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEK 1125 Query: 529 GNRGAPGINGTKGYPGLKGDEGEAGDPGDDNN--DIAPRGVKGAKGYRGPEGPQGPPGHQ 586 G +G G +G +G GL G G G PG+D + +I G KG+KG +G +GP GP G Q Sbjct: 1126 GPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQ 1185 Query: 587 GP---PGP 591 GP PGP Sbjct: 1186 GPIGQPGP 1193 Score = 286 bits (731), Expect = 9e-77 Identities = 169/365 (46%), Positives = 193/365 (52%), Gaps = 35/365 (9%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS---R 313 GPPG G G GERG G G G G PG G GP G +G GEKG +G G + Sbjct: 1078 GPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQ 1137 Query: 314 GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKG---DPGAFGLK 370 GP G G G G G DG KGE+G PG G KG G G GP GP+G PG G Sbjct: 1138 GPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGAD 1197 Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQPGE------PGPPGEKGEAGDEGNPGPDGAPGER 424 GE G G G G+ G GP G G PG PGPPGEKGE GD G GP G PG R Sbjct: 1198 GEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPR 1257 Query: 425 G---GPGERGPR------GTPGTRGPRGDPGEAGP---QGDQGREGPVGVPGDPGEAGPI 472 G PG GP+ G PG G +G+PGEAG G+ G GP G G+ GE+GP Sbjct: 1258 GPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPS 1317 Query: 473 GPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGE---RGEDGPAGN-GTEGFPGFPGYP 528 G G G +GPPG +G +G+PGP G PGDPG GE G+DGP G+ G +G PG G P Sbjct: 1318 GAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSP 1377 Query: 529 GNRGAPGIN---GTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGH 585 G G PG + G +G PG G EG G+ G G++G G GP GPQG PG Sbjct: 1378 GPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGE----AGLEGPPGKTGPIGPQGAPGK 1433 Query: 586 QGPPG 590 GP G Sbjct: 1434 PGPDG 1438 Score = 282 bits (722), Expect = 1e-75 Identities = 163/360 (45%), Positives = 191/360 (53%), Gaps = 26/360 (7%) Query: 257 GPPGLRGDPGFEGERGKPGLPG------EKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310 G PGL G PG +G +G G PG EKG G PG+PG G G G +GE+G RG Sbjct: 868 GVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGIT 927 Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPG---FDGIQGPPGPKGDPGAF 367 G GPKG G G G G G G G G PG KG PG DG+ G PG +G+ G Sbjct: 928 GKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 987 Query: 368 GLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKG------EAGDEGNPGPDGAP 421 G G G PG G G G +GP G+ G PG PGPPGE+G + G +G+PGP G P Sbjct: 988 GKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLP 1047 Query: 422 GERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGD---PGEAGPIGPKGYR 478 G+ G PG RG G G GP G G G +G G GP G PG+ G AGPIG G Sbjct: 1048 GKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRP 1107 Query: 479 GDEGPPGSEGARGAP---GPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFPGYPGNR 531 G +GPPG G +GAP GP GP G GL G G GPAG G +G G G PG + Sbjct: 1108 GPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQK 1167 Query: 532 GAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G+ G G +G PG G +G G PG D P G +G +G G +G +GP G GPPGP Sbjct: 1168 GSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEP-GPRGQQGLFGQKGDEGPRGFPGPPGP 1226 Score = 281 bits (719), Expect = 2e-75 Identities = 170/400 (42%), Positives = 199/400 (49%), Gaps = 71/400 (17%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RG GL G PG +G RG PG G G GD G GD G VG +G+ GE G RG G +GP Sbjct: 630 RGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGP 689 Query: 316 KGYKGEKGKRGIDGVDGVKGEMG---YPGLPGCKGSPGFDGIQGPPG---PKGDPGAFGL 369 G G G G+DG G KG +G PG PG +G+PG G+ GP G P G+ G G Sbjct: 690 PGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGK 749 Query: 370 KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGE---------------------KGE 408 G G PGADG G PG GP G++G G PGP G KGE Sbjct: 750 PGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGE 809 Query: 409 AGDEGNPGPDGAPGERG--------GP-GERGPRGTPGTRGPRGDPGEAGPQGDQGREGP 459 G++G PG G G +G GP GE GP G G GP GDPG GP G++G+ G Sbjct: 810 KGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGV 869 Query: 460 VGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGE--------- 510 G+PG PG GP G G+ G G G +G RG PG GP G G G RGE Sbjct: 870 PGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGK 929 Query: 511 ---------DGPAG-------NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGD---EGE 551 DGPAG NG +G GFPG G G PG +G G+PG +G+ +G+ Sbjct: 930 PGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGK 989 Query: 552 AGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G PG P GV G +G G GP G GH GPPGP Sbjct: 990 TGPPG-------PPGVVGPQGPTGETGPMGERGHPGPPGP 1022 Score = 276 bits (705), Expect = 9e-74 Identities = 170/404 (42%), Positives = 197/404 (48%), Gaps = 65/404 (16%) Query: 253 QPARGPPGL--RGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEK------ 304 +PA PG+ G PG EG G PG PG G G G PG+ GP G G+ G Sbjct: 457 EPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPP 516 Query: 305 ----------GSRGEKGSRGPKGYKGE--------------KGKRGIDGVDGVKGEMGYP 340 G G+ GS+GP E +G G G+ G G +G P Sbjct: 517 GTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPP 576 Query: 341 GLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEP 400 G G KG PG G QGP G +G PG G G +G G+DG G PG +GP GD G G Sbjct: 577 GSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLA 636 Query: 401 GPPGEKGEAGD---EGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGRE 457 G PGEKG GD G PGP G GERG GE GPRG PG GPRG G GP G G Sbjct: 637 GLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPP 696 Query: 458 GPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGP---AGPPGD------PGLMGER 508 G G+ G PG G +GP+G G G G+ GA+G PGP GPPG+ PGL G Sbjct: 697 GVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMP 756 Query: 509 GEDGPAGN-GTEGFPGFP------------GYPGNRGAPGINGTKGYPGLKGDEGEAGDP 555 G DGP G+ G EG PG GYPG RG G +G +G G KG++GE G P Sbjct: 757 GADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFP 816 Query: 556 G--------DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G D +I P G +G G GP+G GP G GP GP Sbjct: 817 GFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGP 860 Score = 275 bits (702), Expect = 2e-73 Identities = 155/337 (45%), Positives = 183/337 (54%), Gaps = 29/337 (8%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 +GPPG G+PG GE+G+PG EAG+PG PG+ GP G +G +GEKG G G+ GP Sbjct: 1269 QGPPGGIGNPGAVGEKGEPG------EAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGP 1322 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375 G KG G DG G G +G+PG PG G PG G GPPG KGD GE G+ Sbjct: 1323 PGPKGPPGD---DGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGD------DGEPGQ 1373 Query: 376 PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGT 435 G+ G G PG SGP G G PG GP G +GE G +G G +G PG+ G GP+G Sbjct: 1374 TGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGK---TGPIGPQGA 1430 Query: 436 PGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGP 495 PG GP G G GP G+QG G G G PG GP G G +GD GP G +G G G Sbjct: 1431 PGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGL 1490 Query: 496 AGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGD 554 GPPG+ G G+RG GP G +G +G G G G G PG G G PG KG +G +G Sbjct: 1491 IGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSG- 1549 Query: 555 PGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 P G KG G+ GP GP GPPG P P Sbjct: 1550 ---------PTGPKGEAGHPGPPGPPGPPGEVIQPLP 1577 Score = 268 bits (686), Expect = 1e-71 Identities = 164/379 (43%), Positives = 190/379 (50%), Gaps = 53/379 (13%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQG----MKGEKGSRGEKGS 312 GP GL G PG G G+ G PGE+G G PG PG G G G + G G+ GS Sbjct: 475 GPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGS 534 Query: 313 RGPKGYKGE--------------KGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPP 358 +GP E +G G G+ G G +G PG G KG PG G QGP Sbjct: 535 KGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPR 594 Query: 359 GPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPD 418 G +G PG G G +G G+DG G PG +GP GD G G G PGEKG GD G GP Sbjct: 595 GVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPP 654 Query: 419 GAPG---ERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475 G PG ERG GE GPRG PG GPRG G GP G G G G+ G PG G +GP+ Sbjct: 655 GPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQ 714 Query: 476 GYRGDEGPPGSEGARGAPGPAG---PPGD------PGLMGERGEDGPAGN-GTEGFPGFP 525 G G G G+ GA+G PGP G PPG+ PGL G G DGP G+ G EG PG Sbjct: 715 GEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEK 774 Query: 526 G------------YPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573 G YPG RG G +G +G G KG++GE G PG KG G Sbjct: 775 GGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPG----------FKGDMGI 824 Query: 574 RGPEGPQGPPGHQGPPGPD 592 +G G GPPG +G GP+ Sbjct: 825 KGDRGEIGPPGPRGEDGPE 843 Score = 246 bits (628), Expect = 8e-65 Identities = 149/362 (41%), Positives = 177/362 (48%), Gaps = 36/362 (9%) Query: 260 GLRGDPGFEGERGKP----------GLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGE 309 G+ G G +G++G+P G PG +G AG PG PG +GP G G GE+G G Sbjct: 444 GIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGR 503 Query: 310 KGSRGPKGYKGEKG-------KRGIDGVDGVKGEMG-----------YPGLPGCKGSPGF 351 G G G G G + G G G KG M +G G Sbjct: 504 PGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGP 563 Query: 352 DGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD 411 G+ G PGP G PG+ GLKGE G+ G G G G GP+G G+ G G G +G G Sbjct: 564 MGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQ 623 Query: 412 EGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGP 471 G G G G G PGE+G RG PG GP G PG+ G +GD G GP G+PG+PG G Sbjct: 624 TGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGL 683 Query: 472 IGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGN 530 +GPKG G GPPG G G PGP G +G +GE GP G G G G PG G Sbjct: 684 LGPKGPPGPPGPPGVTGMDGQPGPKGN------VGPQGEPGPPGQQGNPGAQGLPGPQGA 737 Query: 531 RGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G PG G G PGL G G G PG + P G KG +G GP+GP G PG +G G Sbjct: 738 IGPPGEKGPLGKPGLPGMPGADGPPGHPGKE-GPPGEKGGQGPPGPQGPIGYPGPRGVKG 796 Query: 591 PD 592 D Sbjct: 797 AD 798 Score = 121 bits (303), Expect = 4e-27 Identities = 115/384 (29%), Positives = 142/384 (36%), Gaps = 127/384 (33%) Query: 320 GEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGAD 379 G++ GI D V E Y P + G +G + P P DPGA GA+ Sbjct: 328 GKEEDVGIGDYDYVPSEDYYTPSPYDDLTYG-EGEENPDQPT-DPGA----------GAE 375 Query: 380 GEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEG---------NP--GPDGAPGERGGPG 428 +S S PGE G +GE +E +P P +P E G PG Sbjct: 376 IPTSTADTSNSSNPAPPPGE-GADDLEGEFTEETIRNLDENYYDPYYDPTSSPSEIG-PG 433 Query: 429 ERGPRGT--PGTRGPRGDPGEAGP----------QGDQGREGPVGVPGDPGEAGPIGPKG 476 + T G GPRG+ G+ G +G G EGP G+PG PG GP G G Sbjct: 434 MPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVG 493 Query: 477 YRGDEGPPGSEGARGAPGPAGPP------------------------------------- 499 G+ GPPG G GA G GPP Sbjct: 494 DPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQA 553 Query: 500 -----GDPGLMGERGEDGPAG-------------------NGTEGFPGFPGYPGNRGAPG 535 G G MG G GP G G +G PG G PG RG G Sbjct: 554 RLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAG 613 Query: 536 INGTKGYP---------------GLKGDEGEAGDPG--------------DDNNDIAPRG 566 +G +G P GL G++G GDPG D+ ++ PRG Sbjct: 614 SDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRG 673 Query: 567 VKGAKGYRGPEGPQGPPGHQGPPG 590 + G G RG GP+GPPG GPPG Sbjct: 674 LPGEPGPRGLLGPKGPPGPPGPPG 697 Score = 47.8 bits (112), Expect = 5e-05 Identities = 29/69 (42%), Positives = 31/69 (44%), Gaps = 6/69 (8%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312 Q + GP G +G G G G PG PG PG PG G G G G KG G G Sbjct: 1509 QGSSGPKGEQGITGPSGPIGPPGPPGL------PGPPGPKGAKGSSGPTGPKGEAGHPGP 1562 Query: 313 RGPKGYKGE 321 GP G GE Sbjct: 1563 PGPPGPPGE 1571 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 309 bits (792), Expect = 8e-84 Identities = 182/369 (49%), Positives = 206/369 (55%), Gaps = 41/369 (11%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RGP GL G G G+ G+PG PG G G GRPGD GP QG G G+ GE G GP Sbjct: 533 RGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGP---QGKVGPSGAPGEDGRPGP 589 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375 G +G +G+ G+ G G KG G PG G KG PG G++G PG G+ GA G G G Sbjct: 590 PGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGP 649 Query: 376 PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPG------ERGGPGE 429 G GE G PG PSG +G PG PGPPGE G+ GD+G PG GAPG ERG PGE Sbjct: 650 AGERGEQGAPG---PSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE 706 Query: 430 RG---------PRG---TPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY 477 RG PRG TPGT GP+G G AGP G QG G G+PG+ G AG GPKG Sbjct: 707 RGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGD 766 Query: 478 RGD------EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGN 530 RGD EG PG +G RG GP GPPG G GE+GE GP G G+ G G PG G Sbjct: 767 RGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGE 826 Query: 531 RGAP------GINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGP---EGPQG 581 G P G G G PG KG++GEAG GD P+G GA G +GP GP+G Sbjct: 827 TGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAP-GPQGPSGAPGPQGPTGVTGPKG 885 Query: 582 PPGHQGPPG 590 G QGPPG Sbjct: 886 ARGAQGPPG 894 Score = 300 bits (767), Expect = 6e-81 Identities = 169/347 (48%), Positives = 191/347 (55%), Gaps = 27/347 (7%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGE------KGEAGDPGRPGDLGPVGYQGMKGEKGSRGE 309 RG PG RG PG +G +G GLPG KG +G G PG GP G QGM GE+G+ G Sbjct: 701 RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 760 Query: 310 KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGL 369 G +G +G GEKG G G DG +G G G PG G+ G G GPPGP G GA G Sbjct: 761 AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA 820 Query: 370 KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGE 429 GE+GE G G AG G G G G GE G G+KG+AG G GP GAPG +G G Sbjct: 821 PGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGV 880 Query: 430 RGPRGTPGTRGP---RGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGS 486 GP+G G +GP G PG AG G G G G PG PG +G GPKG RGD GPPG Sbjct: 881 TGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGR 940 Query: 487 EGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNR---GAPGINGTKGYP 543 G G GPAGPPG+ GE G+DGP +G EG PG G G R G PG G +G+P Sbjct: 941 AGEPGLQGPAGPPGE---KGEPGDDGP--SGAEGPPGPQGLAGQRGIVGLPGQRGERGFP 995 Query: 544 GLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 GL G GE G +G GA G RGP GP GPPG GP G Sbjct: 996 GLPGPSGEPG----------KQGAPGASGDRGPPGPVGPPGLTGPAG 1032 Score = 298 bits (763), Expect = 2e-80 Identities = 163/345 (47%), Positives = 187/345 (54%), Gaps = 14/345 (4%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RGPPG G PG +G +G PG PGE G +G G G GP G G GE G G+ G RGP Sbjct: 209 RGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGP 268 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375 G +G +G G G+ GVKG GYPGL G KG G G++G G G+ G+ G G +G Sbjct: 269 PGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGL 328 Query: 376 PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGT 435 PG G G G++G G++GQPG GPPG G AG G PG GA GE G G RGP G Sbjct: 329 PGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGA 388 Query: 436 PGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGP---IGPKGYRGDEGPPGSEGARGA 492 G RG G PG GP G G G G+PG G AG G G+ G GPPG +GA G Sbjct: 389 QGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGP 448 Query: 493 PGPAGPPGDPGLMGERGEDGPAGN----GTEGFPGFPGYPGNRGA---PGINGTKGYPGL 545 GP G G+PG+ G +GE GP G G +G PG G G RGA PG G G PG Sbjct: 449 LGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGE 508 Query: 546 KGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 +G G G PG D G KGA G RGP G GP G G PG Sbjct: 509 RGAPGNRGFPGQD----GLAGPKGAPGERGPSGLAGPKGANGDPG 549 Score = 292 bits (747), Expect = 1e-78 Identities = 165/360 (45%), Positives = 195/360 (54%), Gaps = 36/360 (10%) Query: 255 ARGPPGLRGDPGFEGERGKPGL---PGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG 311 A G PG G PG +G G PG+ PG G G PG G GP+G +G GE G G KG Sbjct: 406 ASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKG 465 Query: 312 SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKG 371 +GPKG G G +G G G +G+ G G PG G G G +G PG +G PG GL G Sbjct: 466 EQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAG 525 Query: 372 EKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKG------EAGDEGNPGPDGAPGERG 425 KG PG G +G G G +GD G+PGEPG PG +G +AG +G GP GAPGE G Sbjct: 526 PKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDG 585 Query: 426 GPGERGPRGT---------PGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAG------ 470 PG GP+G PG +G G+PG+AG +G G G G+PG GE G Sbjct: 586 RPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG 645 Query: 471 PIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGN 530 P GP G RG++G PG G +G PGP GPPG+ G G++G G A G PG G G Sbjct: 646 PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA-----GAPGLVGPRGE 700 Query: 531 RGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 RG PG G+ G GL+G G G PG D G KGA G GP G QGPPG QG PG Sbjct: 701 RGFPGERGSPGAQGLQGPRGLPGTPGTD-------GPKGASGPAGPPGAQGPPGLQGMPG 753 Score = 291 bits (746), Expect = 2e-78 Identities = 186/476 (39%), Positives = 215/476 (45%), Gaps = 138/476 (28%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDP------------GRPGDLGP------ 294 Q ARG PG G PG +G RG PGL G KGEAG P G PG +GP Sbjct: 272 QGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGE 331 Query: 295 ---------------------------------VGYQGMKGEKGSRGEKGSRGPKGYKGE 321 G+ G G KG G G+RGP+G +G Sbjct: 332 RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGP 391 Query: 322 KGKRGI------------DGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK-------- 361 +G+ G G DG+ G G G PG G+PGF G +GPPGP+ Sbjct: 392 RGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGP 451 Query: 362 ----GDPGAFGLKGE---KGEPGADGEAGRPGSSGPSGDEGQPGEP------GPPGEKGE 408 G+PG G KGE KGEPG G G PG +G G G GEP GPPGE+G Sbjct: 452 KGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGA 511 Query: 409 AGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGE 468 G+ G PG DG G +G PGERGP G G +G GDPG G G G G G PGD G Sbjct: 512 PGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGP 571 Query: 469 AGPIGPKGYRGDE---GPPGSEGARGAP-------------------------------- 493 G +GP G G++ GPPG +GARG P Sbjct: 572 QGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGL 631 Query: 494 -------GPAGPPGDPGLMGERGEDG-PAGNGTEGFPGFPGYPGNRGAP---GINGTKGY 542 G AGPPG G GERGE G P +G +G PG PG PG G P G+ G G Sbjct: 632 PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA 691 Query: 543 PGLKGDEGEAGDPGDDNNDIA-----PRGVKGAKGYRGPE---GPQGPPGHQGPPG 590 PGL G GE G PG+ + A PRG+ G G GP+ GP GPPG QGPPG Sbjct: 692 PGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPG 747 Score = 291 bits (746), Expect = 2e-78 Identities = 167/382 (43%), Positives = 196/382 (51%), Gaps = 44/382 (11%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPG------RPGDLGPVGYQGMKGEKGS 306 Q ARG PG+ G PG +G G+PG GEKG G PG + G+ G G G G G Sbjct: 593 QGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGE 652 Query: 307 RGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366 RGE+G+ GP G++G G G G G G+ G PG G G G G +G PG +G PGA Sbjct: 653 RGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGA 712 Query: 367 FGLKGEKGEPG---------ADGEAGRPGSSGPSGDEGQPGEPGPPG---EKGEAGDEGN 414 GL+G +G PG A G AG PG+ GP G +G PGE G G KG+ GD G Sbjct: 713 QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGE 772 Query: 415 PGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGP 474 GP+GAPG+ GG G GP G PG G G+ GE GP G G G G PG+ GE GP GP Sbjct: 773 KGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP 832 Query: 475 KGY------------RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG----NGT 518 G+ +G++G G +G GAPGP GP G PG G G GP G G Sbjct: 833 AGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP 892 Query: 519 EGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEG 578 G GFPG G G PG NG G PG G G+ G G D P G G G +GP G Sbjct: 893 PGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA-RGDSGPPGRAGEPGLQGPAG 951 Query: 579 P---------QGPPGHQGPPGP 591 P GP G +GPPGP Sbjct: 952 PPGEKGEPGDDGPSGAEGPPGP 973 Score = 291 bits (745), Expect = 2e-78 Identities = 159/352 (45%), Positives = 193/352 (54%), Gaps = 20/352 (5%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRG---EKGS 312 +G G +G+PG G +G PG GE+G+ G G PG +GP+G G +G G+RG + G Sbjct: 464 KGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGL 523 Query: 313 RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372 GPKG GE+G G+ G G G+ G PG PG G+ G G G GP+G G G GE Sbjct: 524 AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE 583 Query: 373 KGEPG------ADGEAGRPGSSGPSGDEGQPGE------PGPPGEKGEAGDEGNPGPDGA 420 G PG A G+ G G GP G G+PG+ PG PG +G G +G G G Sbjct: 584 DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP 643 Query: 421 PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480 PG G GERG +G PG G +G PG GP G+ G+ G GVPG+ G G +GP+G RG Sbjct: 644 PGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 703 Query: 481 EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGT 539 G GS GA+G GP G PG PG G +G GPAG G +G PG G PG RGA GI G Sbjct: 704 PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP 763 Query: 540 KGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 KG G G++G G PG D RG+ G G GP G G G GPPGP Sbjct: 764 KGDRGDVGEKGPEGAPGKDGG----RGLTGPIGPPGPAGANGEKGEVGPPGP 811 Score = 291 bits (744), Expect = 3e-78 Identities = 163/379 (43%), Positives = 190/379 (50%), Gaps = 43/379 (11%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314 A G G G PG G G G PGE+GE G PG G GP G G G KG +GE G +G Sbjct: 799 ANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKG 858 Query: 315 ------PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFG 368 P+G G G +G GV G KG G G PG G PG G GPPG G+PG G Sbjct: 859 DAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG 918 Query: 369 LKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPG 428 G G+ G G G G G +G+ G G GPPGEKGE GD+G G +G PG +G G Sbjct: 919 PPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAG 978 Query: 429 ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEG 488 +RG G PG RG RG PG GP G+ G++G G GD G GP+GP G G G PG EG Sbjct: 979 QRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREG 1038 Query: 489 ARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGL--- 545 + GA GP G G G+ G+RGE G G G PG PG PG G G G +G G Sbjct: 1039 SPGADGPPGRDGAAGVKGDRGETGAV--GAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1096 Query: 546 ------------------KGDEGEAGDPGDDN--------------NDIAPRGVKGAKGY 573 +GD+GEAG+PG+ P G +GA G Sbjct: 1097 MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP 1156 Query: 574 RGPEGPQGPPGHQGPPGPD 592 GP GP+GPPG GP G D Sbjct: 1157 AGPSGPRGPPGPVGPSGKD 1175 Score = 290 bits (743), Expect = 4e-78 Identities = 160/362 (44%), Positives = 193/362 (53%), Gaps = 30/362 (8%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RG G G GF+G G PG PGE G+ GD G PG+ G G G +GE+G GE+GS G Sbjct: 653 RGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGA 712 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375 +G +G +G G G DG KG G G PG +G PG +QG PG +G G G KG++G+ Sbjct: 713 QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPG---LQGMPGERGAAGIAGPKGDRGD 769 Query: 376 PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGT 435 G G G PG G G G G PGP G GE G+ G PGP G+ G RG PGERG G Sbjct: 770 VGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGP 829 Query: 436 PGTR------------GPRGDPGEAGPQGDQGREGPVGVPGDPGEAGP---IGPKGYRGD 480 PG G +G+ GEAG +GD G GP G G PG GP GPKG RG Sbjct: 830 PGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGA 889 Query: 481 EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGT 539 +GPPG+ G GA G GPPG G G G GP+G +G +G G G PG G PG+ G Sbjct: 890 QGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGP 949 Query: 540 KGYPGLKGDEGEAGDPGDD-----------NNDIAPRGVKGAKGYRGPEGPQGPPGHQGP 588 G PG KG+ G+ G G + + G +G +G+ G GP G PG QG Sbjct: 950 AGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 1009 Query: 589 PG 590 PG Sbjct: 1010 PG 1011 Score = 285 bits (729), Expect = 2e-76 Identities = 162/355 (45%), Positives = 184/355 (51%), Gaps = 30/355 (8%) Query: 255 ARGPPGLRGDPGFEGERGKPGL---PGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG 311 A G G G PG +G RG+PG+ PG KG G+PG+ G+ G G G++G G GE G Sbjct: 580 APGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETG 639 Query: 312 SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKG 371 + GP G G G+RG G G G G PG PG G G G QG PG G PG G +G Sbjct: 640 AAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRG 699 Query: 372 EKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERG 431 E+G PG E G PG+ G G G PG PG G KG +G G PG G PG +G PGERG Sbjct: 700 ERGFPG---ERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERG 756 Query: 432 PRGTPGTRGPRGDPGEAGPQGDQGRE------------GPVGVPGDPGEAGPIGPKGYRG 479 G G +G RGD GE GP+G G++ GP G G+ GE GP GP G G Sbjct: 757 AAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAG 816 Query: 480 DEGPPGSEGARGAPGP---AGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGI 536 G PG G G PGP AGPPG G G +GE G AG +G G PG G GAPG Sbjct: 817 ARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQ--KGDAGAPGPQGPSGAPGP 874 Query: 537 NGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G G G KG G G PG G GA G GP G G PG GPPGP Sbjct: 875 QGPTGVTGPKGARGAQGPPG-------ATGFPGAAGRVGPPGSNGNPGPPGPPGP 922 Score = 282 bits (722), Expect = 1e-75 Identities = 165/374 (44%), Positives = 189/374 (50%), Gaps = 39/374 (10%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GPPG G PG +GE+G+ G G+ G G G G GP G G+ G KG+RG +G G Sbjct: 837 GPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGAT 896 Query: 317 GYKGEKGK---------------RGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361 G+ G G+ G G DG KG G G PG G PG G GPPG K Sbjct: 897 GFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEK 956 Query: 362 GDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQ---PGEPGPPGEKGE------AGDE 412 G+PG G G +G PG G AG+ G G G G+ PG PGP GE G+ +GD Sbjct: 957 GEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDR 1016 Query: 413 GNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPV---GVPGDPGEA 469 G PGP G PG G GE G G+PG GP G G AG +GD+G G V G PG PG Sbjct: 1017 GPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSP 1076 Query: 470 GPIGPKGYRGDE---------GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTE 519 GP GP G +GD GP G GARG GP GP GD G GE GE G G+ G Sbjct: 1077 GPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFT 1136 Query: 520 GFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDD--NNDIAPRGVKGAKGYRGPE 577 G G PG PG G G +G G G +G G G G D N P G G +G G Sbjct: 1137 GLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGET 1196 Query: 578 GPQGPPGHQGPPGP 591 GP GPPG+ GPPGP Sbjct: 1197 GPAGPPGNPGPPGP 1210 Score = 281 bits (718), Expect = 3e-75 Identities = 163/384 (42%), Positives = 195/384 (50%), Gaps = 48/384 (12%) Query: 255 ARGPPGLRGDPGFE---------------GERGKPGLPGE------------KGEAGDPG 287 A+GPPGL+G PG GE+G G PG+ G AG G Sbjct: 742 AQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANG 801 Query: 288 RPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKG 347 G++GP G G G +G+ GE+G GP G G G G DG G KGE G G G G Sbjct: 802 EKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG 861 Query: 348 SPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSS---GPSGDEGQPGEPGPPG 404 +PG G G PGP+G G G KG +G G G G PG++ GP G G PG PGPPG Sbjct: 862 APGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 921 Query: 405 EKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEA------GPQGDQGREG 458 G+ G +G G G PG G PG +GP G PG +G GD G + GPQG G+ G Sbjct: 922 PSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRG 981 Query: 459 PVGVPGDPGE---AGPIGPKGYRGDEGPPGSEGARGAPGPAGPP------GDPGLMGERG 509 VG+PG GE G GP G G +G PG+ G RG PGP GPP G+PG G G Sbjct: 982 IVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPG 1041 Query: 510 EDGPAG-NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGD--DNNDIAPRG 566 DGP G +G G G G G GAPG G G PG G G+ GD G+ + P G Sbjct: 1042 ADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSG 1101 Query: 567 VKGAKGYRGPEGPQGPPGHQGPPG 590 GA+G +GP+GP+G G G PG Sbjct: 1102 PAGARGIQGPQGPRGDKGEAGEPG 1125 Score = 275 bits (704), Expect = 1e-73 Identities = 162/369 (43%), Positives = 190/369 (51%), Gaps = 55/369 (14%) Query: 263 GDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEK 322 G PG +G++G+PG K G G PG GP G QG +G++G +GEKG+ GP+G GE Sbjct: 98 GQPGPKGQKGEPG--DIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 155 Query: 323 GKRGIDGVDGVKGEMGYPGLPG---CKGSPGFD------------GIQGPPGPKGDPGAF 367 G G G G G G PGL G + + GFD G GP GP+G PG Sbjct: 156 GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 215 Query: 368 GLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAG------DEGNPGPDGA- 420 G G +G G GE G PG SGP G G PG PG PG+ GEAG + G PGP GA Sbjct: 216 GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGAR 275 Query: 421 --PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREG---------PVGVPGDPGEA 469 PG G PG +G RG PG G +G+ G G +G+ G G P G+PG+ G Sbjct: 276 GFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRT 335 Query: 470 GPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-------NGTEGFP 522 GP G G RG++G PG G G GPAG PG PG G +GE GP G G G P Sbjct: 336 GPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEP 395 Query: 523 GFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGP 582 G PG PG GA G GT G PG KG G AP G+ GA G+ GP GP GP Sbjct: 396 GTPGSPGPAGASGNPGTDGIPGAKGSAG------------AP-GIAGAPGFPGPRGPPGP 442 Query: 583 PGHQGPPGP 591 G GP GP Sbjct: 443 QGATGPLGP 451 Score = 274 bits (701), Expect = 3e-73 Identities = 156/360 (43%), Positives = 188/360 (52%), Gaps = 24/360 (6%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 +GP G +G G G++G+ G PG +G G+PG PG+ GP G G G G G ++ Sbjct: 125 QGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMA 184 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK-- 373 G+ + G + + G G MG G PG G+PG G QG PG G+PG G G + Sbjct: 185 GGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGP 244 Query: 374 ----GEPGADGEAGRPGSS---GPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGG 426 G+PG DGEAG+PG + GP G +G G PG PG G G G PG DGA GE G Sbjct: 245 PGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGA 304 Query: 427 PGER------GPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480 PG + G G+PG GPRG PGE G G G G G G PG AGP GP G G Sbjct: 305 PGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGG 364 Query: 481 EGPPGSEGARGAPGPAGPPGDPGLMGERGE------DGPAG-NGTEGFPGFPGYPGNRGA 533 G PG+ GA+G GP G G G G RGE GPAG +G G G PG G+ GA Sbjct: 365 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA 424 Query: 534 PGINGTKGYPGLKGDEGEAGDPG--DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 PGI G G+PG +G G G G G+ G KG +GP+G GP G QG PGP Sbjct: 425 PGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGP 484 Score = 273 bits (699), Expect = 5e-73 Identities = 168/413 (40%), Positives = 199/413 (48%), Gaps = 75/413 (18%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP------------------ 294 Q G G RGD G +GE+G PG G GE G PG PG GP Sbjct: 125 QGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMA 184 Query: 295 ---------------VGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGY 339 G G G +G G G+ GP+G++G G+ G GV G G G Sbjct: 185 GGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGP 244 Query: 340 PGLPGC------KGSPGFDGIQGPPGPK------GDPGAFGLKGEKGEPGAD---GEAGR 384 PG PG G PG G +GPPGP+ G PG G+KG +G PG D GEAG Sbjct: 245 PGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGA 304 Query: 385 PGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGD 444 PG G SG G+ G PGP G +G G+ G GP GA G RG G+ GP G PG GP G Sbjct: 305 PGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGG 364 Query: 445 P---------GEAGP---QGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGA 492 P GEAGP +G +G +GP G PG PG GP G G G +G PG++G+ GA Sbjct: 365 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA 424 Query: 493 PGPAGPPGDPGLMGERGEDGPAG-------NGTEGFPGFPGYPGNRGAPGINGTKGYPGL 545 PG AG PG PG G G G G G G GF G G +G PG G +G PG Sbjct: 425 PGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGP 484 Query: 546 KGDEGEAGDPGDDN--NDIAPRGVKGAKGYR------GPEGPQGPPGHQGPPG 590 G+EG+ G G+ I P G +GA G R G GP+G PG +GP G Sbjct: 485 AGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSG 537 Score = 273 bits (699), Expect = 5e-73 Identities = 156/358 (43%), Positives = 180/358 (50%), Gaps = 26/358 (7%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312 Q G PG +G G G +G G G G G PG G +GP G G G G G G Sbjct: 866 QGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGK 925 Query: 313 RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK---GDPGAFGL 369 GPKG +G+ G G G G++G G PG G G G G +GPPGP+ G G GL Sbjct: 926 DGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGL 985 Query: 370 KGEKGE------PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD---EGNPGPDGA 420 G++GE PG GE G+ G+ G SGD G PG GPPG G AG+ EG+PG DG Sbjct: 986 PGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP 1045 Query: 421 PGERGGPGERGPR------GTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGP 474 PG G G +G R G PG GP G PG AGP G QG G G G G +GP G Sbjct: 1046 PGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGA 1105 Query: 475 KGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGA 533 +G +G +GP G +G G PG G G G G +G GP G +G +G G G G RG Sbjct: 1106 RGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGP 1165 Query: 534 PGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 PG G G G G G G PG PRG G G GP G GPPG GPPGP Sbjct: 1166 PGPVGPSGKDGANGIPGPIGPPG-------PRGRSGETGPAGPPGNPGPPGPPGPPGP 1216 Score = 186 bits (472), Expect = 1e-46 Identities = 105/257 (40%), Positives = 129/257 (50%), Gaps = 52/257 (20%) Query: 387 SSGPSGDEGQPGEP----------GPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436 +SG G +GQ GEP GPPG +G AG++G G G GE+G PG RG G P Sbjct: 96 ASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 155 Query: 437 GTRGPRGDPGEAGPQGD---------------------------QGREGPVGVPGDPGEA 469 GT G G PG GP G QG GP+G G PG A Sbjct: 156 GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 215 Query: 470 GPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDG----------PAGNGTE 519 G GP+G++G+ G PG G G GP GPPG PG G+ GE G P G Sbjct: 216 GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGAR 275 Query: 520 GFPGFPGYP---GNRGAPGINGTKGYPGLKGDEGEAGDPGDDNN--DIAPRGVKGAKGYR 574 GFPG PG P G+RG PG++G KG G G +GE+G PG++ + + PRG+ G +G Sbjct: 276 GFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRT 335 Query: 575 GPEGPQGPPGHQGPPGP 591 GP G G G+ G PGP Sbjct: 336 GPAGAAGARGNDGQPGP 352 Score = 120 bits (302), Expect = 5e-27 Identities = 77/179 (43%), Positives = 87/179 (48%), Gaps = 33/179 (18%) Query: 425 GGPGERGPRGTPGTR----GPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480 G PG +G +G PG GP+G PG PQG G +GP G GD GE G GP RG Sbjct: 98 GQPGPKGQKGEPGDIKDIVGPKGPPG---PQGPAGEQGPRGDRGDKGEKGAPGP---RGR 151 Query: 481 EGPPGSEGARGAPGPAGPPGDPGLMGE------RGEDGPAGNGTEGFPGFPGYP-GNRGA 533 +G PG+ G G PGP GPPG PGL G G D AG G P P G RG Sbjct: 152 DGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGP 211 Query: 534 PGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592 PG G G G +G+ GE G+PG GP GP+GPPG G PG D Sbjct: 212 PGPAGAPGPQGFQGNPGEPGEPG----------------VSGPMGPRGPPGPPGKPGDD 254 Score = 88.6 bits (218), Expect = 3e-17 Identities = 57/140 (40%), Positives = 65/140 (46%), Gaps = 17/140 (12%) Query: 467 GEAGPIGPKGYRGDEGPPGSEGARGAPGP----AGPPGDPGLMGERGEDGPAGN------ 516 GE PI P G PG +G +G PG GP G PG G GE GP G+ Sbjct: 83 GECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGE 142 Query: 517 ----GTEGFPGFPGYPGNRGAPGINGTKGYPGLKGD-EGEAGDPGDDNNDIAPRGVKGAK 571 G G G PG PGN G PG G G PGL G+ + D+ A GV + Sbjct: 143 KGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV--MQ 200 Query: 572 GYRGPEGPQGPPGHQGPPGP 591 G GP GP+GPPG G PGP Sbjct: 201 GPMGPMGPRGPPGPAGAPGP 220 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 309 bits (792), Expect = 8e-84 Identities = 182/369 (49%), Positives = 206/369 (55%), Gaps = 41/369 (11%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RGP GL G G G+ G+PG PG G G GRPGD GP QG G G+ GE G GP Sbjct: 464 RGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGP---QGKVGPSGAPGEDGRPGP 520 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375 G +G +G+ G+ G G KG G PG G KG PG G++G PG G+ GA G G G Sbjct: 521 PGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGP 580 Query: 376 PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPG------ERGGPGE 429 G GE G PG PSG +G PG PGPPGE G+ GD+G PG GAPG ERG PGE Sbjct: 581 AGERGEQGAPG---PSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE 637 Query: 430 RG---------PRG---TPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY 477 RG PRG TPGT GP+G G AGP G QG G G+PG+ G AG GPKG Sbjct: 638 RGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGD 697 Query: 478 RGD------EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGN 530 RGD EG PG +G RG GP GPPG G GE+GE GP G G+ G G PG G Sbjct: 698 RGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGE 757 Query: 531 RGAP------GINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGP---EGPQG 581 G P G G G PG KG++GEAG GD P+G GA G +GP GP+G Sbjct: 758 TGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAP-GPQGPSGAPGPQGPTGVTGPKG 816 Query: 582 PPGHQGPPG 590 G QGPPG Sbjct: 817 ARGAQGPPG 825 Score = 300 bits (767), Expect = 6e-81 Identities = 169/347 (48%), Positives = 191/347 (55%), Gaps = 27/347 (7%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGE------KGEAGDPGRPGDLGPVGYQGMKGEKGSRGE 309 RG PG RG PG +G +G GLPG KG +G G PG GP G QGM GE+G+ G Sbjct: 632 RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 691 Query: 310 KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGL 369 G +G +G GEKG G G DG +G G G PG G+ G G GPPGP G GA G Sbjct: 692 AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA 751 Query: 370 KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGE 429 GE+GE G G AG G G G G GE G G+KG+AG G GP GAPG +G G Sbjct: 752 PGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGV 811 Query: 430 RGPRGTPGTRGP---RGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGS 486 GP+G G +GP G PG AG G G G G PG PG +G GPKG RGD GPPG Sbjct: 812 TGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGR 871 Query: 487 EGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNR---GAPGINGTKGYP 543 G G GPAGPPG+ GE G+DGP +G EG PG G G R G PG G +G+P Sbjct: 872 AGEPGLQGPAGPPGE---KGEPGDDGP--SGAEGPPGPQGLAGQRGIVGLPGQRGERGFP 926 Query: 544 GLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 GL G GE G +G GA G RGP GP GPPG GP G Sbjct: 927 GLPGPSGEPG----------KQGAPGASGDRGPPGPVGPPGLTGPAG 963 Score = 298 bits (763), Expect = 2e-80 Identities = 163/345 (47%), Positives = 187/345 (54%), Gaps = 14/345 (4%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RGPPG G PG +G +G PG PGE G +G G G GP G G GE G G+ G RGP Sbjct: 140 RGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGP 199 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375 G +G +G G G+ GVKG GYPGL G KG G G++G G G+ G+ G G +G Sbjct: 200 PGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGL 259 Query: 376 PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGT 435 PG G G G++G G++GQPG GPPG G AG G PG GA GE G G RGP G Sbjct: 260 PGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGA 319 Query: 436 PGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGP---IGPKGYRGDEGPPGSEGARGA 492 G RG G PG GP G G G G+PG G AG G G+ G GPPG +GA G Sbjct: 320 QGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGP 379 Query: 493 PGPAGPPGDPGLMGERGEDGPAGN----GTEGFPGFPGYPGNRGA---PGINGTKGYPGL 545 GP G G+PG+ G +GE GP G G +G PG G G RGA PG G G PG Sbjct: 380 LGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGE 439 Query: 546 KGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 +G G G PG D G KGA G RGP G GP G G PG Sbjct: 440 RGAPGNRGFPGQD----GLAGPKGAPGERGPSGLAGPKGANGDPG 480 Score = 292 bits (747), Expect = 1e-78 Identities = 165/360 (45%), Positives = 195/360 (54%), Gaps = 36/360 (10%) Query: 255 ARGPPGLRGDPGFEGERGKPGL---PGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG 311 A G PG G PG +G G PG+ PG G G PG G GP+G +G GE G G KG Sbjct: 337 ASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKG 396 Query: 312 SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKG 371 +GPKG G G +G G G +G+ G G PG G G G +G PG +G PG GL G Sbjct: 397 EQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAG 456 Query: 372 EKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKG------EAGDEGNPGPDGAPGERG 425 KG PG G +G G G +GD G+PGEPG PG +G +AG +G GP GAPGE G Sbjct: 457 PKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDG 516 Query: 426 GPGERGPRGT---------PGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAG------ 470 PG GP+G PG +G G+PG+AG +G G G G+PG GE G Sbjct: 517 RPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG 576 Query: 471 PIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGN 530 P GP G RG++G PG G +G PGP GPPG+ G G++G G A G PG G G Sbjct: 577 PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA-----GAPGLVGPRGE 631 Query: 531 RGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 RG PG G+ G GL+G G G PG D G KGA G GP G QGPPG QG PG Sbjct: 632 RGFPGERGSPGAQGLQGPRGLPGTPGTD-------GPKGASGPAGPPGAQGPPGLQGMPG 684 Score = 291 bits (746), Expect = 2e-78 Identities = 186/476 (39%), Positives = 215/476 (45%), Gaps = 138/476 (28%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDP------------GRPGDLGP------ 294 Q ARG PG G PG +G RG PGL G KGEAG P G PG +GP Sbjct: 203 QGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGE 262 Query: 295 ---------------------------------VGYQGMKGEKGSRGEKGSRGPKGYKGE 321 G+ G G KG G G+RGP+G +G Sbjct: 263 RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGP 322 Query: 322 KGKRGI------------DGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK-------- 361 +G+ G G DG+ G G G PG G+PGF G +GPPGP+ Sbjct: 323 RGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGP 382 Query: 362 ----GDPGAFGLKGE---KGEPGADGEAGRPGSSGPSGDEGQPGEP------GPPGEKGE 408 G+PG G KGE KGEPG G G PG +G G G GEP GPPGE+G Sbjct: 383 KGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGA 442 Query: 409 AGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGE 468 G+ G PG DG G +G PGERGP G G +G GDPG G G G G G PGD G Sbjct: 443 PGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGP 502 Query: 469 AGPIGPKGYRGDE---GPPGSEGARGAP-------------------------------- 493 G +GP G G++ GPPG +GARG P Sbjct: 503 QGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGL 562 Query: 494 -------GPAGPPGDPGLMGERGEDG-PAGNGTEGFPGFPGYPGNRGAP---GINGTKGY 542 G AGPPG G GERGE G P +G +G PG PG PG G P G+ G G Sbjct: 563 PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA 622 Query: 543 PGLKGDEGEAGDPGDDNNDIA-----PRGVKGAKGYRGPE---GPQGPPGHQGPPG 590 PGL G GE G PG+ + A PRG+ G G GP+ GP GPPG QGPPG Sbjct: 623 PGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPG 678 Score = 291 bits (746), Expect = 2e-78 Identities = 167/382 (43%), Positives = 196/382 (51%), Gaps = 44/382 (11%) Query: 253 QPARGPPGLRGDPGFEGERGKP------GLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGS 306 Q ARG PG+ G PG +G G+P GLPG G G PG+ G+ G G G G G Sbjct: 524 QGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGE 583 Query: 307 RGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366 RGE+G+ GP G++G G G G G G+ G PG G G G G +G PG +G PGA Sbjct: 584 RGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGA 643 Query: 367 FGLKGEKGEP---------GADGEAGRPGSSGPSGDEGQPGEPGP---PGEKGEAGDEGN 414 GL+G +G P GA G AG PG+ GP G +G PGE G G KG+ GD G Sbjct: 644 QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGE 703 Query: 415 PGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGP 474 GP+GAPG+ GG G GP G PG G G+ GE GP G G G G PG+ GE GP GP Sbjct: 704 KGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP 763 Query: 475 KGY------------RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG----NGT 518 G+ +G++G G +G GAPGP GP G PG G G GP G G Sbjct: 764 AGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP 823 Query: 519 EGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEG 578 G GFPG G G PG NG G PG G G+ G P D P G G G +GP G Sbjct: 824 PGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDG-PKGARGDSGPPGRAGEPGLQGPAG 882 Query: 579 P---------QGPPGHQGPPGP 591 P GP G +GPPGP Sbjct: 883 PPGEKGEPGDDGPSGAEGPPGP 904 Score = 291 bits (745), Expect = 2e-78 Identities = 159/352 (45%), Positives = 193/352 (54%), Gaps = 20/352 (5%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRG---EKGS 312 +G G +G+PG G +G PG GE+G+ G G PG +GP+G G +G G+RG + G Sbjct: 395 KGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGL 454 Query: 313 RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372 GPKG GE+G G+ G G G+ G PG PG G+ G G G GP+G G G GE Sbjct: 455 AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE 514 Query: 373 KGEPG------ADGEAGRPGSSGPSGDEGQPGE------PGPPGEKGEAGDEGNPGPDGA 420 G PG A G+ G G GP G G+PG+ PG PG +G G +G G G Sbjct: 515 DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP 574 Query: 421 PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480 PG G GERG +G PG G +G PG GP G+ G+ G GVPG+ G G +GP+G RG Sbjct: 575 PGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 634 Query: 481 EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGT 539 G GS GA+G GP G PG PG G +G GPAG G +G PG G PG RGA GI G Sbjct: 635 PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP 694 Query: 540 KGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 KG G G++G G PG D RG+ G G GP G G G GPPGP Sbjct: 695 KGDRGDVGEKGPEGAPGKDGG----RGLTGPIGPPGPAGANGEKGEVGPPGP 742 Score = 291 bits (744), Expect = 3e-78 Identities = 163/379 (43%), Positives = 190/379 (50%), Gaps = 43/379 (11%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314 A G G G PG G G G PGE+GE G PG G GP G G G KG +GE G +G Sbjct: 730 ANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKG 789 Query: 315 ------PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFG 368 P+G G G +G GV G KG G G PG G PG G GPPG G+PG G Sbjct: 790 DAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG 849 Query: 369 LKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPG 428 G G+ G G G G G +G+ G G GPPGEKGE GD+G G +G PG +G G Sbjct: 850 PPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAG 909 Query: 429 ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEG 488 +RG G PG RG RG PG GP G+ G++G G GD G GP+GP G G G PG EG Sbjct: 910 QRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREG 969 Query: 489 ARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGL--- 545 + GA GP G G G+ G+RGE G G G PG PG PG G G G +G G Sbjct: 970 SPGADGPPGRDGAAGVKGDRGETGAV--GAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1027 Query: 546 ------------------KGDEGEAGDPGDDN--------------NDIAPRGVKGAKGY 573 +GD+GEAG+PG+ P G +GA G Sbjct: 1028 MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP 1087 Query: 574 RGPEGPQGPPGHQGPPGPD 592 GP GP+GPPG GP G D Sbjct: 1088 AGPSGPRGPPGPVGPSGKD 1106 Score = 290 bits (743), Expect = 4e-78 Identities = 160/362 (44%), Positives = 193/362 (53%), Gaps = 30/362 (8%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RG G G GF+G G PG PGE G+ GD G PG+ G G G +GE+G GE+GS G Sbjct: 584 RGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGA 643 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375 +G +G +G G G DG KG G G PG +G PG +QG PG +G G G KG++G+ Sbjct: 644 QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPG---LQGMPGERGAAGIAGPKGDRGD 700 Query: 376 PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGT 435 G G G PG G G G G PGP G GE G+ G PGP G+ G RG PGERG G Sbjct: 701 VGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGP 760 Query: 436 PGTR------------GPRGDPGEAGPQGDQGREGPVGVPGDPGEAGP---IGPKGYRGD 480 PG G +G+ GEAG +GD G GP G G PG GP GPKG RG Sbjct: 761 PGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGA 820 Query: 481 EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGT 539 +GPPG+ G GA G GPPG G G G GP+G +G +G G G PG G PG+ G Sbjct: 821 QGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGP 880 Query: 540 KGYPGLKGDEGEAGDPGDD-----------NNDIAPRGVKGAKGYRGPEGPQGPPGHQGP 588 G PG KG+ G+ G G + + G +G +G+ G GP G PG QG Sbjct: 881 AGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 940 Query: 589 PG 590 PG Sbjct: 941 PG 942 Score = 285 bits (729), Expect = 2e-76 Identities = 162/355 (45%), Positives = 184/355 (51%), Gaps = 30/355 (8%) Query: 255 ARGPPGLRGDPGFEGERGKPGL---PGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG 311 A G G G PG +G RG+PG+ PG KG G+PG+ G+ G G G++G G GE G Sbjct: 511 APGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETG 570 Query: 312 SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKG 371 + GP G G G+RG G G G G PG PG G G G QG PG G PG G +G Sbjct: 571 AAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRG 630 Query: 372 EKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERG 431 E+G PG E G PG+ G G G PG PG G KG +G G PG G PG +G PGERG Sbjct: 631 ERGFPG---ERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERG 687 Query: 432 PRGTPGTRGPRGDPGEAGPQGDQGRE------------GPVGVPGDPGEAGPIGPKGYRG 479 G G +G RGD GE GP+G G++ GP G G+ GE GP GP G G Sbjct: 688 AAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAG 747 Query: 480 DEGPPGSEGARGAPGP---AGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGI 536 G PG G G PGP AGPPG G G +GE G AG +G G PG G GAPG Sbjct: 748 ARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQ--KGDAGAPGPQGPSGAPGP 805 Query: 537 NGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G G G KG G G PG G GA G GP G G PG GPPGP Sbjct: 806 QGPTGVTGPKGARGAQGPPG-------ATGFPGAAGRVGPPGSNGNPGPPGPPGP 853 Score = 282 bits (722), Expect = 1e-75 Identities = 165/374 (44%), Positives = 189/374 (50%), Gaps = 39/374 (10%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GPPG G PG +GE+G+ G G+ G G G G GP G G+ G KG+RG +G G Sbjct: 768 GPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGAT 827 Query: 317 GYKGEKGK---------------RGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361 G+ G G+ G G DG KG G G PG G PG G GPPG K Sbjct: 828 GFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEK 887 Query: 362 GDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQ---PGEPGPPGEKGE------AGDE 412 G+PG G G +G PG G AG+ G G G G+ PG PGP GE G+ +GD Sbjct: 888 GEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDR 947 Query: 413 GNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPV---GVPGDPGEA 469 G PGP G PG G GE G G+PG GP G G AG +GD+G G V G PG PG Sbjct: 948 GPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSP 1007 Query: 470 GPIGPKGYRGDE---------GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTE 519 GP GP G +GD GP G GARG GP GP GD G GE GE G G+ G Sbjct: 1008 GPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFT 1067 Query: 520 GFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDD--NNDIAPRGVKGAKGYRGPE 577 G G PG PG G G +G G G +G G G G D N P G G +G G Sbjct: 1068 GLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGET 1127 Query: 578 GPQGPPGHQGPPGP 591 GP GPPG+ GPPGP Sbjct: 1128 GPAGPPGNPGPPGP 1141 Score = 281 bits (718), Expect = 3e-75 Identities = 163/384 (42%), Positives = 195/384 (50%), Gaps = 48/384 (12%) Query: 255 ARGPPGLRGDPGFE---------------GERGKPGLPGE------------KGEAGDPG 287 A+GPPGL+G PG GE+G G PG+ G AG G Sbjct: 673 AQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANG 732 Query: 288 RPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKG 347 G++GP G G G +G+ GE+G GP G G G G DG G KGE G G G G Sbjct: 733 EKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG 792 Query: 348 SPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSS---GPSGDEGQPGEPGPPG 404 +PG G G PGP+G G G KG +G G G G PG++ GP G G PG PGPPG Sbjct: 793 APGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 852 Query: 405 EKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEA------GPQGDQGREG 458 G+ G +G G G PG G PG +GP G PG +G GD G + GPQG G+ G Sbjct: 853 PSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRG 912 Query: 459 PVGVPGDPGE---AGPIGPKGYRGDEGPPGSEGARGAPGPAGPP------GDPGLMGERG 509 VG+PG GE G GP G G +G PG+ G RG PGP GPP G+PG G G Sbjct: 913 IVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPG 972 Query: 510 EDGPAG-NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGD--DNNDIAPRG 566 DGP G +G G G G G GAPG G G PG G G+ GD G+ + P G Sbjct: 973 ADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSG 1032 Query: 567 VKGAKGYRGPEGPQGPPGHQGPPG 590 GA+G +GP+GP+G G G PG Sbjct: 1033 PAGARGIQGPQGPRGDKGEAGEPG 1056 Score = 274 bits (701), Expect = 3e-73 Identities = 156/360 (43%), Positives = 188/360 (52%), Gaps = 24/360 (6%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 +GP G +G G G++G+ G PG +G G+PG PG+ GP G G G G G ++ Sbjct: 56 QGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMA 115 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK-- 373 G+ + G + + G G MG G PG G+PG G QG PG G+PG G G + Sbjct: 116 GGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGP 175 Query: 374 ----GEPGADGEAGRPGSS---GPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGG 426 G+PG DGEAG+PG + GP G +G G PG PG G G G PG DGA GE G Sbjct: 176 PGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGA 235 Query: 427 PGER------GPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480 PG + G G+PG GPRG PGE G G G G G G PG AGP GP G G Sbjct: 236 PGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGG 295 Query: 481 EGPPGSEGARGAPGPAGPPGDPGLMGERGE------DGPAG-NGTEGFPGFPGYPGNRGA 533 G PG+ GA+G GP G G G G RGE GPAG +G G G PG G+ GA Sbjct: 296 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA 355 Query: 534 PGINGTKGYPGLKGDEGEAGDPG--DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 PGI G G+PG +G G G G G+ G KG +GP+G GP G QG PGP Sbjct: 356 PGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGP 415 Score = 273 bits (699), Expect = 5e-73 Identities = 168/413 (40%), Positives = 199/413 (48%), Gaps = 75/413 (18%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP------------------ 294 Q G G RGD G +GE+G PG G GE G PG PG GP Sbjct: 56 QGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMA 115 Query: 295 ---------------VGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGY 339 G G G +G G G+ GP+G++G G+ G GV G G G Sbjct: 116 GGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGP 175 Query: 340 PGLPGC------KGSPGFDGIQGPPGPK------GDPGAFGLKGEKGEPGAD---GEAGR 384 PG PG G PG G +GPPGP+ G PG G+KG +G PG D GEAG Sbjct: 176 PGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGA 235 Query: 385 PGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGD 444 PG G SG G+ G PGP G +G G+ G GP GA G RG G+ GP G PG GP G Sbjct: 236 PGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGG 295 Query: 445 P---------GEAGP---QGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGA 492 P GEAGP +G +G +GP G PG PG GP G G G +G PG++G+ GA Sbjct: 296 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA 355 Query: 493 PGPAGPPGDPGLMGERGEDGPAG-------NGTEGFPGFPGYPGNRGAPGINGTKGYPGL 545 PG AG PG PG G G G G G G GF G G +G PG G +G PG Sbjct: 356 PGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGP 415 Query: 546 KGDEGEAGDPGDDN--NDIAPRGVKGAKGYR------GPEGPQGPPGHQGPPG 590 G+EG+ G G+ I P G +GA G R G GP+G PG +GP G Sbjct: 416 AGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSG 468 Score = 273 bits (699), Expect = 5e-73 Identities = 156/358 (43%), Positives = 180/358 (50%), Gaps = 26/358 (7%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312 Q G PG +G G G +G G G G G PG G +GP G G G G G G Sbjct: 797 QGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGK 856 Query: 313 RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK---GDPGAFGL 369 GPKG +G+ G G G G++G G PG G G G G +GPPGP+ G G GL Sbjct: 857 DGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGL 916 Query: 370 KGEKGE------PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD---EGNPGPDGA 420 G++GE PG GE G+ G+ G SGD G PG GPPG G AG+ EG+PG DG Sbjct: 917 PGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP 976 Query: 421 PGERGGPGERGPR------GTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGP 474 PG G G +G R G PG GP G PG AGP G QG G G G G +GP G Sbjct: 977 PGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGA 1036 Query: 475 KGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGA 533 +G +G +GP G +G G PG G G G G +G GP G +G +G G G G RG Sbjct: 1037 RGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGP 1096 Query: 534 PGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 PG G G G G G G PG PRG G G GP G GPPG GPPGP Sbjct: 1097 PGPVGPSGKDGANGIPGPIGPPG-------PRGRSGETGPAGPPGNPGPPGPPGPPGP 1147 Score = 273 bits (698), Expect = 6e-73 Identities = 161/367 (43%), Positives = 189/367 (51%), Gaps = 55/367 (14%) Query: 265 PGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGK 324 PG +G++G+PG K G G PG GP G QG +G++G +GEKG+ GP+G GE G Sbjct: 31 PGPKGQKGEPG--DIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT 88 Query: 325 RGIDGVDGVKGEMGYPGLPG---CKGSPGFD------------GIQGPPGPKGDPGAFGL 369 G G G G G PGL G + + GFD G GP GP+G PG G Sbjct: 89 PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGA 148 Query: 370 KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAG------DEGNPGPDGA--- 420 G +G G GE G PG SGP G G PG PG PG+ GEAG + G PGP GA Sbjct: 149 PGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGF 208 Query: 421 PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREG---------PVGVPGDPGEAGP 471 PG G PG +G RG PG G +G+ G G +G+ G G P G+PG+ G GP Sbjct: 209 PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGP 268 Query: 472 IGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-------NGTEGFPGF 524 G G RG++G PG G G GPAG PG PG G +GE GP G G G PG Sbjct: 269 AGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGT 328 Query: 525 PGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPG 584 PG PG GA G GT G PG KG G AP G+ GA G+ GP GP GP G Sbjct: 329 PGSPGPAGASGNPGTDGIPGAKGSAG------------AP-GIAGAPGFPGPRGPPGPQG 375 Query: 585 HQGPPGP 591 GP GP Sbjct: 376 ATGPLGP 382 Score = 176 bits (445), Expect = 1e-43 Identities = 101/254 (39%), Positives = 125/254 (49%), Gaps = 61/254 (24%) Query: 399 EPGPPGEKGEAGD-------EGNPGPDGAPGERGGPGERGPR---------------GTP 436 +PGP G+KGE GD +G PGP G GE+G G+RG + GTP Sbjct: 30 QPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTP 89 Query: 437 GTRGPRGDPGEAGPQG------------------------DQGREGPVGVPGDPGEAGPI 472 G GP G PG GP G QG GP+G G PG AG Sbjct: 90 GNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAP 149 Query: 473 GPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDG----------PAGNGTEGFP 522 GP+G++G+ G PG G G GP GPPG PG G+ GE G P G GFP Sbjct: 150 GPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFP 209 Query: 523 GFPGYP---GNRGAPGINGTKGYPGLKGDEGEAGDPGDDNN--DIAPRGVKGAKGYRGPE 577 G PG P G+RG PG++G KG G G +GE+G PG++ + + PRG+ G +G GP Sbjct: 210 GTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPA 269 Query: 578 GPQGPPGHQGPPGP 591 G G G+ G PGP Sbjct: 270 GAAGARGNDGQPGP 283 Score = 119 bits (298), Expect = 1e-26 Identities = 76/177 (42%), Positives = 86/177 (48%), Gaps = 33/177 (18%) Query: 427 PGERGPRGTPGTR----GPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEG 482 PG +G +G PG GP+G PG PQG G +GP G GD GE G GP RG +G Sbjct: 31 PGPKGQKGEPGDIKDIVGPKGPPG---PQGPAGEQGPRGDRGDKGEKGAPGP---RGRDG 84 Query: 483 PPGSEGARGAPGPAGPPGDPGLMGE------RGEDGPAGNGTEGFPGFPGYP-GNRGAPG 535 PG+ G G PGP GPPG PGL G G D AG G P P G RG PG Sbjct: 85 EPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPG 144 Query: 536 INGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592 G G G +G+ GE G+PG GP GP+GPPG G PG D Sbjct: 145 PAGAPGPQGFQGNPGEPGEPG----------------VSGPMGPRGPPGPPGKPGDD 185 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 308 bits (788), Expect = 2e-83 Identities = 171/364 (46%), Positives = 196/364 (53%), Gaps = 33/364 (9%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GP G G PG +G G+PG PG KG+ G G PG +G G G GE+G RG +G GP Sbjct: 419 GPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPT 478 Query: 317 GYKGEKGKRG---------IDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAF 367 G G G+RG DGV G KG G G PG G G G G PG G PGA Sbjct: 479 GLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAK 538 Query: 368 GLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGP 427 GL G G PG DG+ G PG P+G +G+PG PGPPG +G+AG G PGP GA GE G Sbjct: 539 GLTGSPGSPGPDGKTGPPG---PAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA 595 Query: 428 GERGPRGTPGTRGP---------RGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYR 478 GERG G PG GP +G PG AGP G++G +GP G PG G GP GP G Sbjct: 596 GERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEA 655 Query: 479 GDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFPGYPGNRGAP 534 G G G G GAPGP+G G+ G GERG GP G G G PG G G+ GAP Sbjct: 656 GKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAP 715 Query: 535 GINGTKGYPGLKGDEGEAG-----DPGDDNNDIAPRGVKGA---KGYRGPEGPQGPPGHQ 586 G G++G PGL+G GE G P D D P+G G+ G RG GP GPPG Sbjct: 716 GAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPA 775 Query: 587 GPPG 590 G PG Sbjct: 776 GAPG 779 Score = 304 bits (778), Expect = 3e-82 Identities = 175/380 (46%), Positives = 200/380 (52%), Gaps = 45/380 (11%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RG G G PGF+G G G PGE G+ G+ G PGDLG G G +GE+G GE+G +GP Sbjct: 631 RGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGP 690 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGP------PGPKGDPGAFGL 369 G G +G G G DG KG+ G PG PG +G+PG G+ G PGPKGD G G Sbjct: 691 PGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGP 750 Query: 370 KGEKGEPGADGEAGRPGSSGPSGDEGQP---GEPGPPGEKGEAGDEGNPGPDGAPGERGG 426 KG G PG DG G G GP G G P GE GP G G G G PG G PG G Sbjct: 751 KGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGP 810 Query: 427 PGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPI---GPKGYRGDEGP 483 G GP G G G +G+PG+AG +GD G GP G G PG G + G KG RG GP Sbjct: 811 AGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGP 870 Query: 484 PGSEGARGA------PGP---AGPPGDPGLMGE------RGEDGPAGN-GTEGFPGFPGY 527 PG+ G GA PGP AGPPG PG G+ RGE GPAG G G PG PG Sbjct: 871 PGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGP 930 Query: 528 PGNRGAPGINGTKGYP---------------GLKGDEGEAGDPG--DDNNDIAPRGVKGA 570 G +G+PG +G G P GL G GE G PG + + +G GA Sbjct: 931 AGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGA 990 Query: 571 KGYRGPEGPQGPPGHQGPPG 590 G RGP GP GPPG GPPG Sbjct: 991 SGERGPPGPMGPPGLAGPPG 1010 Score = 298 bits (762), Expect = 2e-80 Identities = 169/351 (48%), Positives = 186/351 (52%), Gaps = 23/351 (6%) Query: 257 GPPGLRGDPGFEGERGKPGLPG------EKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310 GP G G+PG GERG PG PG + GEAG G PG GP G +G +G GS G + Sbjct: 584 GPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQ 643 Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370 G GP G GE GK G GV G G G G G +G PG G+QGPPGP G GA G Sbjct: 644 GLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAP 703 Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGP---PGEKGEAGDEGNPGPDGAPGERGGP 427 G G G G G PGS G G +G PGE G PG KG+ GD G G DG+PG+ G Sbjct: 704 GNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVR 763 Query: 428 GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487 G GP G PG G GD GE+GP G G G G PGD GE GP GP G+ G G G Sbjct: 764 GLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQP 823 Query: 488 GARGAPGPAGPPGD---PGLMGERGEDGPAGN----GTEGFPGFPGYPGNRGAPGINGTK 540 GA+G PG AG GD PG G G GP GN G +G G G PG G PG G Sbjct: 824 GAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRV 883 Query: 541 GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G PG G+ G G PG P G +G KG RG GP G PG GPPGP Sbjct: 884 GPPGPSGNAGPPGPPG-------PAGKEGGKGPRGETGPAGRPGEVGPPGP 927 Score = 297 bits (761), Expect = 3e-80 Identities = 180/412 (43%), Positives = 202/412 (49%), Gaps = 77/412 (18%) Query: 256 RGPPGLRGDPGFEG---------ERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGS 306 RG PG RG PG +G ERG PG G KG G+ GRPG+ G G +G+ G GS Sbjct: 487 RGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGS 546 Query: 307 RGEKGSRGPKGYKGEKGKRGIDGVDGVKGE---MGYPGLPGCKGSPGFDGIQGPPGPKGD 363 G G GP G G+ G+ G G G +G+ MG+PG G G PG G +G PGP G Sbjct: 547 PGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGA 606 Query: 364 PGAFGLKGEKG------------EPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD 411 G G GE G E G G AG PG G G G PGE G PGE+G GD Sbjct: 607 VGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGD 666 Query: 412 EGNPGPDGAPGERGGPGERGPRGTPGTRGPR------------GDPGEAGPQGDQGREGP 459 G PGP GA GERG PGERG +G PG GPR GD G G G QG G Sbjct: 667 LGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGL 726 Query: 460 VGVPGDPGEAGPIGPKGYRGDEGP------PGSEGARGAPGPAGPPGDPGLMGERGEDGP 513 G+PG+ G AG GPKG RGD GP PG +G RG GP GPPG G G++GE GP Sbjct: 727 QGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGP 786 Query: 514 AG----------------------NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGE 551 +G G G PG G PG +G PG G KG G G G Sbjct: 787 SGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGP 846 Query: 552 AGDPGDDNNDIAPRGVKGAKGYRGPE------------GPQGPPGHQGPPGP 591 AG PG N AP G KGA+G GP GP GP G+ GPPGP Sbjct: 847 AGPPGPIGNVGAP-GAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGP 897 Score = 294 bits (752), Expect = 3e-79 Identities = 175/400 (43%), Positives = 193/400 (48%), Gaps = 66/400 (16%) Query: 255 ARGPPGLRGDP------GFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRG 308 ARG PG RG+P GF G G G PG KGE GD G GD GP G G G G G Sbjct: 795 ARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIG 854 Query: 309 EKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYP------GLPGCKGSPGFDGIQGP----- 357 G+ G KG +G G G G G G +G P G PG G G +G +GP Sbjct: 855 NVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETG 914 Query: 358 ----PGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEG 413 PG G PG G GEKG PGADG AG PG+ GP G GQ G G PG++GE G G Sbjct: 915 PAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPG 974 Query: 414 NPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIG 473 PGP G PG++G G G RG P GP G PG AGP G+ GREG G G PG G G Sbjct: 975 LPGPSGEPGKQGPSGASGERGPP---GPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPG 1031 Query: 474 PKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG------------------ 515 KG RG+ GP G GA GAPG GP G G G+RGE GPAG Sbjct: 1032 AKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQG 1091 Query: 516 -------------------NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPG 556 G G G PG PG+ G G +G G G +G G AG PG Sbjct: 1092 PRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPG 1151 Query: 557 DDN-----NDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 D I P G +G G GP GP GPPG GPPGP Sbjct: 1152 KDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGP 1191 Score = 293 bits (751), Expect = 4e-79 Identities = 175/403 (43%), Positives = 200/403 (49%), Gaps = 69/403 (17%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGE---------AGDPGRPGDLGPVGYQGM---KGEK 304 G PG G G GERG+PG PG G AG PG G GP G+ G KGE Sbjct: 296 GAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEA 355 Query: 305 GSRGEKGSRGPKGYKGEKGK---------RGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQ 355 G +G +GS GP+G +GE G G G DG G G G PG G+PGF G + Sbjct: 356 GPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGAR 415 Query: 356 GPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP 415 GP GP+G G G KG GEPGA G G G+ G G G G PGP GE+G+ G G P Sbjct: 416 GPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEP 475 Query: 416 GP---DGAPGERGGPGER---------------GPRGTPGTRGPRGDPGEAGPQGDQGRE 457 GP G PGERGGPG R G RG+PG GP+G PGEAG G+ G Sbjct: 476 GPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLP 535 Query: 458 GPVGVPGDP------GEAGPIGPKGYRGDEGPPGSEGARGA------PGPAGPPGDPGLM 505 G G+ G P G+ GP GP G G GPPG GARG PGP G G+PG Sbjct: 536 GAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA 595 Query: 506 GERGEDGPAG----------NGTEGFPGFPGYPGNRGAPGINGTKGY---PGLKGDEGEA 552 GERG GP G G +G PG G G RG G G+ G+ PG G GEA Sbjct: 596 GERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEA 655 Query: 553 GDPGD-----DNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G PG+ D P G +G +G+ G G QGPPG GP G Sbjct: 656 GKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRG 698 Score = 293 bits (750), Expect = 6e-79 Identities = 172/375 (45%), Positives = 196/375 (52%), Gaps = 51/375 (13%) Query: 253 QPARGPPGLRGDPGFE---GERGKPGLP---GEKGEAGDPGRPGDLGPVGYQGMKGEKGS 306 Q +GPPG G+PG G RG PG P G+ GEAG PGRPG+ GP G QG +G G+ Sbjct: 199 QGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGT 258 Query: 307 RGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366 G G +G +G+ G G +G G G KGE PG PG G+PG G +G PG +G PGA Sbjct: 259 AGLPGMKGHRGFSGLDGAKGDAGPAGPKGE---PGSPGENGAPGQMGPRGLPGERGRPGA 315 Query: 367 FGLKGEKGEPGADGEAGRPGSSGPSGDEGQP------------------------GEPGP 402 G G +G GA G AG PG +GP+G G P GEPGP Sbjct: 316 PGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGP 375 Query: 403 PGEKGEAGDEGNPGPDGAPGER---GGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGP 459 PG G AG GNPG DG PG + G PG G G PG RGP G G GP G +G G Sbjct: 376 PGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGE 435 Query: 460 VGVP---GDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN 516 G P GD G G GP G +G GP G EG RGA G GP G PG GERG G Sbjct: 436 PGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERG-----GP 490 Query: 517 GTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGP 576 G+ GFPG G G +G G G+ G G KG GEAG PG+ G+ GAKG G Sbjct: 491 GSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGE-------AGLPGAKGLTGS 543 Query: 577 EGPQGPPGHQGPPGP 591 G GP G GPPGP Sbjct: 544 PGSPGPDGKTGPPGP 558 Score = 292 bits (748), Expect = 1e-78 Identities = 172/387 (44%), Positives = 199/387 (51%), Gaps = 54/387 (13%) Query: 255 ARGPPGLRGDPGFEGERG---------------KPGLPGEKGEAGDPGRPGDLGPVGYQG 299 A GP G RG+ GF GERG PG G KG+AG PG PG G G QG Sbjct: 669 APGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQG 728 Query: 300 MKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPG 359 M GE+G+ G G +G +G G KG G G DGV+G G G PG G+PG G GP G Sbjct: 729 MPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSG 788 Query: 360 PKGDPGAFGLKGEKGEPGADGEAG---------RPGSSGPSGDEGQPGEPGPPGEKGEAG 410 P G GA G G++GEPG G AG +PG+ G GD G G+ GPPG G AG Sbjct: 789 PAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAG 848 Query: 411 DEGNPGPDGAPGERG-----GP----------GERGPRGTPGTRGPRGDPGEAGPQGDQG 455 G G GAPG +G GP G GP G G GP G PG AG +G +G Sbjct: 849 PPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKG 908 Query: 456 REGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDG-PA 514 G G G PGE GP GP G G++G PG++G GAP G PG G+ G+RG G P Sbjct: 909 PRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAP---GTPGPQGIAGQRGVVGLPG 965 Query: 515 GNGTEGFPGFP---GYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAP------- 564 G GFPG P G PG +G G +G +G PG G G AG PG+ + AP Sbjct: 966 QRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPG 1025 Query: 565 -RGVKGAKGYRGPEGPQGPPGHQGPPG 590 G GAKG RG GP GPPG G PG Sbjct: 1026 RDGSPGAKGDRGETGPAGPPGAPGAPG 1052 Score = 291 bits (744), Expect = 3e-78 Identities = 167/369 (45%), Positives = 190/369 (51%), Gaps = 41/369 (11%) Query: 257 GPPGLRGDPGFEGERGKPG---------LPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSR 307 GPPG G PG +GE G G PG++GE G PG G GP G G G KG Sbjct: 770 GPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEP 829 Query: 308 GEKGSRG------PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361 G+ G++G P G G G G G G KG G G PG G PG G GPPGP Sbjct: 830 GDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPS 889 Query: 362 GD------PGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP 415 G+ PG G +G KG G G AGRPG GP G G GE G PG G AG G P Sbjct: 890 GNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTP 949 Query: 416 GPDGAPGERGG---PGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPI 472 GP G G+RG PG+RG RG PG GP G+PG+ GP G G GP G G PG AGP Sbjct: 950 GPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPP 1009 Query: 473 GPKGYRGD---------EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFP 522 G G G +G PG++G RG GPAGPPG PG G G GPAG +G G Sbjct: 1010 GESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGET 1069 Query: 523 GFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGP 582 G G G G G G G G +GD+GE G+ GD RG+KG +G+ G +GP GP Sbjct: 1070 GPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGD-------RGIKGHRGFSGLQGPPGP 1122 Query: 583 PGHQGPPGP 591 PG G GP Sbjct: 1123 PGSPGEQGP 1131 Score = 290 bits (741), Expect = 6e-78 Identities = 160/341 (46%), Positives = 182/341 (53%), Gaps = 12/341 (3%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GP G++G PG GE GK G GE G G PG PG+ G G +G G G G KG G + Sbjct: 452 GPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGER 511 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376 G G G +G G G GE G PG G GSPG G G GP G G G G G P Sbjct: 512 GSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPP 571 Query: 377 GADGEAGRPGSSGPSGDEGQPGE------PGPPGEKGEAGDEGNPGPDGAPGERGGPGER 430 GA G+AG G GP G G+PG+ PGPPG G AG +G G G PG G GER Sbjct: 572 GARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGER 631 Query: 431 GPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGAR 490 G +G G+ G +G PG AGP G+ G+ G GVPGD G GP G RG+ G PG G + Sbjct: 632 GEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGD---LGAPGPSGARGERGFPGERGVQ 688 Query: 491 GAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEG 550 G PGPAGP G G G G G A G G PG G PG +G PG G G PG KGD G Sbjct: 689 GPPGPAGPRGANGAPGNDGAKGDA--GAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRG 746 Query: 551 EAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 +AG G D + GV+G G GP GP G PG +G GP Sbjct: 747 DAGPKGADGSP-GKDGVRGLTGPIGPPGPAGAPGDKGESGP 786 Score = 288 bits (737), Expect = 2e-77 Identities = 166/353 (47%), Positives = 187/353 (52%), Gaps = 20/353 (5%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GP G G PG +G RG G G G AG PG G+ GP G G G +G+ G++G GP Sbjct: 749 GPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPP 808 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD---PGAFGLKGEK 373 G G G G DG G KGE G G G G PG G GPPGP G+ PGA G +G Sbjct: 809 GPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSA 868 Query: 374 GEPGADG---EAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGER 430 G PGA G AGR G GPSG+ G PG PGP G++G G G GP G PGE G PG Sbjct: 869 GPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPP 928 Query: 431 GP---RGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487 GP +G+PG GP G PG GPQG G+ G VG+PG GE G G G G+ G G Sbjct: 929 GPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPS 988 Query: 488 GARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNR---------GAPGIN 537 GA G GP GP G PGL G GE G G G EG PG G PG + G PG Sbjct: 989 GASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAP 1048 Query: 538 GTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G G PG G G++GD G + P G G G RGP GPQGP G +G G Sbjct: 1049 GAPGAPGPVGPAGKSGDRG-ETGPAGPAGPVGPVGARGPAGPQGPRGDKGETG 1100 Score = 285 bits (730), Expect = 1e-76 Identities = 163/369 (44%), Positives = 184/369 (49%), Gaps = 35/369 (9%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP- 315 GP G +G+PG GE G PG G +G G+ GRPG GP G +G G G+ G G GP Sbjct: 281 GPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPA 340 Query: 316 -----------KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDP 364 KG G +G RG +G GV+GE G PG G G G G G PG KG Sbjct: 341 GPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGAN 400 Query: 365 GAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPG-- 422 GA G+ G G PGA G +G G GP G +G GEPG PG KG+ G +G PGP G G Sbjct: 401 GAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPP 460 Query: 423 -------ERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475 +RG GE GP G PG G RG PG G G G GP G G+ G GP GPK Sbjct: 461 GPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPK 520 Query: 476 GYRGDEGPPGSEGARGA---------PGPAGPPGDPGLMGERGEDGPAG----NGTEGFP 522 G G+ G PG G GA PGP G G PG G+ G GP G G G Sbjct: 521 GSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVM 580 Query: 523 GFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGP 582 GFPG G G PG G +G PG G G AG G+ P G G G RG +GP G Sbjct: 581 GFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQ-GPPGPAGPAGERGEQGPAGS 639 Query: 583 PGHQGPPGP 591 PG QG PGP Sbjct: 640 PGFQGLPGP 648 Score = 285 bits (728), Expect = 2e-76 Identities = 164/360 (45%), Positives = 186/360 (51%), Gaps = 33/360 (9%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GP G RG G +G RG+PG PG G AG G PG G G +G G G G G G + Sbjct: 356 GPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGAR 415 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPG---CKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373 G G +G G G G GE G PG G KG PG G+QGPPGP G+ G G +GE Sbjct: 416 GPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEP 475 Query: 374 GE---PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGE---AGDEGNPGPDGAPGERGGP 427 G PG GE G PGS G G +G G GP GE+G AG +G+PG G PGE G P Sbjct: 476 GPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLP 535 Query: 428 GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487 G +G G+PG+ GP G G GP G GR GP G PG G+AG +G G +G G PG Sbjct: 536 GAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA 595 Query: 488 GARGAPGP---------------AGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRG 532 G RG PGP GPPG G GERGE GPAG+ PGF G PG G Sbjct: 596 GERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGS-----PGFQGLPGPAG 650 Query: 533 APGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592 PG G G G+ GD G G G RG G +G +GP GP GP G G PG D Sbjct: 651 PPGEAGKPGEQGVPGDLGAPGPSGARGE----RGFPGERGVQGPPGPAGPRGANGAPGND 706 Score = 282 bits (722), Expect = 1e-75 Identities = 166/373 (44%), Positives = 183/373 (49%), Gaps = 45/373 (12%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314 A+G G G PG +G+ G PG G+ G G PG PG G G G G KG+ GE G G Sbjct: 537 AKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAG 596 Query: 315 PKGYKGEKGKRGIDGVDGVKGEMGYP---------GLPGCKGSPGFDGIQGPPGP----- 360 +G G G G G DG G G P G G GSPGF G+ GP GP Sbjct: 597 ERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAG 656 Query: 361 -------KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEG 413 GD GA G G +GE G GE G G GP+G G G PG G KG+AG G Sbjct: 657 KPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPG 716 Query: 414 NPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGRE------------GPVG 461 PG GAPG +G PGERG G PG +G RGD G G G G++ GP G Sbjct: 717 APGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAG 776 Query: 462 VPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGP---AGPPGDPGLMGERGEDGPAGNGT 518 PGD GE+GP GP G G G PG G G PGP AGPPG G G +GE G A G Sbjct: 777 APGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDA--GA 834 Query: 519 EGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEG 578 +G G PG G G PG G G PG KG G AG PG G GA G GP G Sbjct: 835 KGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPG-------ATGFPGAAGRVGPPG 887 Query: 579 PQGPPGHQGPPGP 591 P G G GPPGP Sbjct: 888 PSGNAGPPGPPGP 900 Score = 280 bits (717), Expect = 4e-75 Identities = 170/381 (44%), Positives = 193/381 (50%), Gaps = 46/381 (12%) Query: 257 GPPGLRGDPGFEGERGKPGL----------------------PGEKGEAGD---PGRPGD 291 G PGL G PG G G PGL PG G +G PG PG Sbjct: 136 GQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGA 195 Query: 292 LGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGF 351 GP G+QG GE G G G GP+G G GK G DG G G G G PG +G+ G Sbjct: 196 PGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGL 255 Query: 352 DGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD 411 G G PG KG G GL G KG+ G G G PGS G +G GQ G G PGE+G G Sbjct: 256 PGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGA 315 Query: 412 EGNPGP---DGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGV---PGD 465 G G DGA G G PG GP G PG G G GEAGPQG +G EGP GV PG Sbjct: 316 PGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGP 375 Query: 466 PGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEGF 521 PG AG GP G G +G PG++GA GAPG AG PG PG G G GP G G G Sbjct: 376 PGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGE 435 Query: 522 PGFPGYPGNRGA---PGINGTKGYPGLKGDEGEAGDPGDDNNDIAP-----RGVKGAKGY 573 PG PG G+ GA PG G +G PG G+EG+ G G+ P RG G++G+ Sbjct: 436 PGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGF 495 Query: 574 RGPE---GPQGPPGHQGPPGP 591 G + GP+GP G +G PGP Sbjct: 496 PGADGVAGPKGPAGERGSPGP 516 Score = 275 bits (702), Expect = 2e-73 Identities = 164/370 (44%), Positives = 180/370 (48%), Gaps = 39/370 (10%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312 Q G G +GD G G RG G PG G G PG PG GP G G G G+ + S Sbjct: 105 QETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLS 164 Query: 313 RG----------PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKG 362 G G G G RG+ G G G G+ G PG G PG G GP GP G Sbjct: 165 YGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPG 224 Query: 363 DPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGE---------KGEAGDEG 413 PG G GE G+PG GE G PG G G G G PG G KG+AG G Sbjct: 225 PPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAG 284 Query: 414 NPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGP-- 471 G G+PGE G PG+ GPRG PG RG G PG AG +G+ G G G PG G AGP Sbjct: 285 PKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPG 344 Query: 472 ----IGPKGYRGDEGPPGSE---GARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEG 520 +G KG G +GP GSE G RG PGP GP G G G G DG G NG G Sbjct: 345 FPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPG 404 Query: 521 FPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQ 580 G PG+PG RG G G G PG KG+ GE G PG +G GAKG GP G Q Sbjct: 405 IAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGS-------KGDTGAKGEPGPVGVQ 457 Query: 581 GPPGHQGPPG 590 GPPG G G Sbjct: 458 GPPGPAGEEG 467 Score = 256 bits (654), Expect = 8e-68 Identities = 158/377 (41%), Positives = 182/377 (48%), Gaps = 58/377 (15%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GP G G PG G GK G G +GE G GRPG++GP G G GEKGS G G G Sbjct: 887 GPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAP 946 Query: 317 GYKGEKG---KRGIDGVDGVKGEMGYPGLPGCKGSPG------FDGIQGPPGPKGDPGAF 367 G G +G +RG+ G+ G +GE G+PGLPG G PG G +GPPGP G PG Sbjct: 947 GTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLA 1006 Query: 368 GLKGEKGE---PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGER 424 G GE G PGA+G GR GS G GD G+ G GPPG G G G GP G G+R Sbjct: 1007 GPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDR 1066 Query: 425 GGPGERGP---------RGTPGTRGPRGDPGEAGPQGDQG---------REGPVGVPGDP 466 G G GP RG G +GPRGD GE G QGD+G +GP G PG P Sbjct: 1067 GETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSP 1126 Query: 467 GEAGPIGPKGYRGDEGPPGSEGA------RGAPGPAGPPGDPGLMGERGEDGPAGNGTEG 520 GE GP G G G GPPGS GA G PGP GPPG G G+ G GP Sbjct: 1127 GEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGP------- 1179 Query: 521 FPGFPGYPGNRGAPGINGTKGY----PGLKGDEGEAGDPGDDNNDIAPRGV--------- 567 PG PG PG G P + P K +G DD N + R + Sbjct: 1180 -PGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRYYRADDANVVRDRDLEVDTTLKSL 1238 Query: 568 -KGAKGYRGPEGPQGPP 583 + + R PEG + P Sbjct: 1239 SQQIENIRSPEGSRKNP 1255 Score = 205 bits (522), Expect = 2e-52 Identities = 122/287 (42%), Positives = 135/287 (47%), Gaps = 36/287 (12%) Query: 340 PGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE 399 P P SP G GPKGD G G +G G PG DG G+PG GP G G PG Sbjct: 93 PVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGP 152 Query: 400 PG----------------------PPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPG 437 PG PG G +G G PGP GAPG +G G G G PG Sbjct: 153 PGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPG 212 Query: 438 TRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYR------------GDEGPPG 485 GP G G GP G G +G G PG PGE GP GP+G R G G G Sbjct: 213 ASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSG 272 Query: 486 SEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGTKGYPG 544 +GA+G GPAGP G+PG GE G G G G G G PG PG GA G +G G G Sbjct: 273 LDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAG 332 Query: 545 LKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G G AG PG + +G G +G RG EGPQG G GPPGP Sbjct: 333 PPGPTGPAGPPGFP-GAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGP 378 Score = 132 bits (332), Expect = 2e-30 Identities = 84/199 (42%), Positives = 98/199 (49%), Gaps = 15/199 (7%) Query: 403 PGEKGEAGDEGNPGPDGA--PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPV 460 PG + G+ PDG+ P ++ G GP+G G RGPRG AGP G G G Sbjct: 82 PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGP---AGPPGRDGIPGQP 138 Query: 461 GVPGDPGEAGPIGPKGYRGDEGPP-------GSEGARGAPGPAGPPGDPGLMGERGEDGP 513 G+PG PG GP GP G G+ P S G PGP GP G GL G G GP Sbjct: 139 GLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGP 198 Query: 514 AGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573 G +G PG PG PG G G G G PG GD+GEAG PG + P G +GA+G Sbjct: 199 --QGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPG-ERGPPGPQGARGL 255 Query: 574 RGPEGPQGPPGHQGPPGPD 592 G G G GH+G G D Sbjct: 256 PGTAGLPGMKGHRGFSGLD 274 Score = 92.4 bits (228), Expect = 2e-18 Identities = 58/158 (36%), Positives = 69/158 (43%), Gaps = 43/158 (27%) Query: 251 ECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310 E PA GPPG G PG G G G G++GE G G G +GPVG +G G +G RG+K Sbjct: 1038 ETGPA-GPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDK 1096 Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGL---------------PGCKGSPGFDGIQ 355 G G +G +G KG RG G+ G G G PG PG G+PG DG+ Sbjct: 1097 GETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLN 1156 Query: 356 G---------------------------PPGPKGDPGA 366 G PPGP G P A Sbjct: 1157 GLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSA 1194 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 305 bits (782), Expect = 1e-82 Identities = 169/357 (47%), Positives = 192/357 (53%), Gaps = 21/357 (5%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG---S 312 +G PG RG G G RG PG GE G G G G GP G G+KGE G G+KG S Sbjct: 815 KGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGS 874 Query: 313 RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372 GP+G G G G +GV G+KG G G PG G PG G GPPGP G PG G GE Sbjct: 875 PGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGE 934 Query: 373 KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGP 432 G+ G G G PGS G GD G G PG PG+KG+ G++G PGPDG PG G G+RG Sbjct: 935 PGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGI 994 Query: 433 RGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGA 492 G PG RG RG PG GP G G+ GP G GD G GP+GP G G G PG EG G Sbjct: 995 VGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGN 1054 Query: 493 PGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFP------------GYPGNR---GAPGI 536 G G G G G+RG+ GPAG G++G PG P G PG+R G PG Sbjct: 1055 DGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGR 1114 Query: 537 NGTKGYPGLKGDEGEAGDPGD--DNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G +G PG +G G+ GD GD D RG G +G GP GP G G G PGP Sbjct: 1115 AGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGP 1171 Score = 298 bits (762), Expect = 2e-80 Identities = 173/393 (44%), Positives = 204/393 (51%), Gaps = 59/393 (15%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G GL G G +GERG G G KG GDPGRPG+ G G +G+ G G +G +G GP Sbjct: 531 GSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPL 590 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGS---------------------PGFDGIQ 355 G GE G+ G G G++G+ G GLPG KGS PG DG Sbjct: 591 GAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEV 650 Query: 356 GPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAG----- 410 GP GP G PG G +GE+G PG G G PG GP G+ G+PG+ G PG+ G G Sbjct: 651 GPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPR 710 Query: 411 -DEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEA 469 + GNPG G PG G PGE+G G G GP+G PG +G GD G G G+PG+ G A Sbjct: 711 GERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIA 770 Query: 470 GPIGPKGYRGD------EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-------- 515 G GPKG RG EG G++GARG PGP GPPG G GE+GE GP G Sbjct: 771 GTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSR 830 Query: 516 --------NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGD------EGEAGDPGDDNND 561 NG G GF G G G PG+ G G PG KGD +G AG PG + Sbjct: 831 GNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPN 890 Query: 562 IAPRGVKGAKGYRGPEGPQGPP---GHQGPPGP 591 P G+KG +G +GP G G P G GPPGP Sbjct: 891 GVP-GLKGGRGTQGPPGATGFPGSAGRVGPPGP 922 Score = 295 bits (754), Expect = 2e-79 Identities = 161/348 (46%), Positives = 190/348 (54%), Gaps = 12/348 (3%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314 ARG PG G PG +G RG GL G KGE G PG G+ GP G G G G RG G RG Sbjct: 286 ARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERG 345 Query: 315 PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKG 374 G +G G+RG G+ G G MG G+PG G PG G++G GP G G G +G++G Sbjct: 346 RLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRG 405 Query: 375 EPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRG 434 E G G G PG G G +G PG GP G G +G G+ GP G+PG +G G +G RG Sbjct: 406 ETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRG 465 Query: 435 TPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPG 494 PG G G GEAGP+G+ G G G G PGE G GP+G G GPPG G RGAPG Sbjct: 466 QPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPG 525 Query: 495 PAGPPGD---PGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEG 550 G PG PG G +GE GP G +G +G G PG PG G PG G G PG++G EG Sbjct: 526 NRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEG 585 Query: 551 EAGD---PGDDN-----NDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 + G PG+D I RG G+ G GP+G G PG G G Sbjct: 586 KLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAG 633 Score = 292 bits (747), Expect = 1e-78 Identities = 179/412 (43%), Positives = 196/412 (47%), Gaps = 83/412 (20%) Query: 257 GPPGLRGD---------PGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSR 307 GPPGL G+ GF+G G PG PGE G+ GD G PGD G VG G +GE+G+ Sbjct: 657 GPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNP 716 Query: 308 GEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDG------IQGPPGPK 361 GE+G G G GEKG G G DG KG G G PG G PG G I G PGPK Sbjct: 717 GERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPK 776 Query: 362 GDPGAFGLKG---------------------------EKGEPGADGEAGRPGS------- 387 GD G G KG EKGEPG G G PGS Sbjct: 777 GDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSR 836 Query: 388 -----------SGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436 +GP G +GQPG G PGE G+ GD G+PGP G G PG GP G P Sbjct: 837 GENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGS---PGPHGPNGVP 893 Query: 437 GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPG------SEGAR 490 G +G RG G G G G G VG PG G GP GP G G EGPPG S G Sbjct: 894 GLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRV 953 Query: 491 GAPGPAGPPGDPGLMGERGED---------GPAG-NGTEGFPGFPGYPGNRGAPGINGTK 540 G GPAGPPG PG G+ GED GPAG G G G PG G RG PG+ G Sbjct: 954 GDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPA 1013 Query: 541 GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592 G PG G G GD G P G G+ G G GP+GP G+ G PG D Sbjct: 1014 GTPGKVGPTGATGDKGPP----GPVGPPGSNGPVGEPGPEGPAGNDGTPGRD 1061 Score = 291 bits (744), Expect = 3e-78 Identities = 159/348 (45%), Positives = 191/348 (54%), Gaps = 20/348 (5%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GP G G G +G G PG G++G GDPG G GPVG +G G +G G G GPK Sbjct: 480 GPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPK 539 Query: 317 GYKGEKGKRGIDGVDGVKGE---MGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373 G +GE+G G G G +G+ G PGLPG +G G G+QGP G G GA G G Sbjct: 540 GAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRP 599 Query: 374 GEPGADGEAGRPGS---SGPSGDEGQPGEPGP------PGEKGEAGDEGNPGPDGAPGER 424 G PG+ G G+PGS GP G G PG+PG PG++G G +G GP G G Sbjct: 600 GPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPP 659 Query: 425 GGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPP 484 G GERG +G PG G +G PG GP G+ G+ G GVPGDPG GP+GP+G R Sbjct: 660 GLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGER------ 713 Query: 485 GSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTKGYP 543 G+ G RG PG G PG+ G+ G G DGP G+ G G PG G PG +G PG G G P Sbjct: 714 GNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTP 773 Query: 544 GLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G KGD G G+ G + G +G G GP GP GP G +G PGP Sbjct: 774 GPKGDRGGIGEKGAEGT-AGNDGARGLPGPLGPPGPAGPTGEKGEPGP 820 Score = 290 bits (742), Expect = 5e-78 Identities = 167/357 (46%), Positives = 189/357 (52%), Gaps = 29/357 (8%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPG------DLGPVGYQGMKGEKGSRGEK 310 GP GL G PG G G PGL G +G G PG G +GP G G G G GE Sbjct: 876 GPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEP 935 Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGI---QGPPGPKGDPGAF 367 G GP G +G+ G G G +G G PG PG KG PG DG GPPGP G G Sbjct: 936 GKEGPPGLRGDPGSHGRVGD---RGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQR 992 Query: 368 GL------KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAP 421 G+ +GE+G PG G AG PG GP+G G G PGP G G G G PGP+G Sbjct: 993 GIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPA 1052 Query: 422 GERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE 481 G G PG G G RG RGDPG AG G QG G G G PG+AG G G RG Sbjct: 1053 GNDGTPGR---DGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPI 1109 Query: 482 GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN----GTEGFPGFPGYPGNRGA---P 534 GPPG G RG PGP GP GD G G+RG+ G G+ G +G PG PG G +G+ P Sbjct: 1110 GPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIP 1169 Query: 535 GINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G G +G PG G G+ G+PG I P GV+G+ G GPEGP G PG GPPGP Sbjct: 1170 GPFGPRGPPGPVGPSGKEGNPG-PLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGP 1225 Score = 289 bits (739), Expect = 1e-77 Identities = 161/362 (44%), Positives = 194/362 (53%), Gaps = 32/362 (8%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQG---------MKGEKG 305 A GP G RG PG G G G PG++G G PG+PG +GP+G G MKGE G Sbjct: 331 AMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAG 390 Query: 306 SRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPG 365 G +G GP+G +GE G G G G+ G +G G PG KG G G GPPG G PG Sbjct: 391 PTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPG 450 Query: 366 AFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGP---------PGEKGEAGDEGNPG 416 + G +G G G G+ G PG G G+ G GEPGP PGE+G+ G G+PG Sbjct: 451 SPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPG 510 Query: 417 ---PDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIG 473 P G GERG PG RG G+ G GP+G GE GP G G +G G PG PGE G G Sbjct: 511 TVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPG 570 Query: 474 PKGYRGD---EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPG 529 +G G+ +GP G G GAPG G PG PG +G RG+ G G G +G G PG PG Sbjct: 571 ARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPG 630 Query: 530 NRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPP 589 G G+ G +G PG G+ G +G G P G+ G +G +GP GP G G GPP Sbjct: 631 EAGNAGVPGQRGAPGKDGEVGPSGPVG-------PPGLAGERGEQGPPGPTGFQGLPGPP 683 Query: 590 GP 591 GP Sbjct: 684 GP 685 Score = 289 bits (739), Expect = 1e-77 Identities = 167/378 (44%), Positives = 193/378 (51%), Gaps = 42/378 (11%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEA------GDPGRPGDLGPVGYQGMKGEKGSRGE 309 RG PG G PG +G G PG PGE G A G PG+ G++GP G G G G RGE Sbjct: 608 RGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGE 667 Query: 310 KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGL 369 +G GP G++G G G G G G+ G PG PG G G G +G PG +G+PG GL Sbjct: 668 QGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGL 727 Query: 370 KGEK---------GEPGADGEAGRPGSSGPSGDEGQPGE------PGPPGEKGEAGDE-- 412 GEK G G+ G +G PG +GP G +G PGE PGP G++G G++ Sbjct: 728 PGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGA 787 Query: 413 ----------------GNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGR 456 G PGP G GE+G PG RG G PG+RG G GE GP G G Sbjct: 788 EGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGF 847 Query: 457 EGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG- 515 GP G G PG G G G +GD G PG +G G+PGP GP G PGL G RG GP G Sbjct: 848 AGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGA 907 Query: 516 NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN--NDIAPRGVKGAKGY 573 G G G G PG GAPG G G PG +G G GDPG D P G G G Sbjct: 908 TGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGD 967 Query: 574 RGPEGPQGPPGHQGPPGP 591 +G G G PG GPPGP Sbjct: 968 KGDPGEDGQPGPDGPPGP 985 Score = 287 bits (734), Expect = 4e-77 Identities = 159/349 (45%), Positives = 182/349 (52%), Gaps = 18/349 (5%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G PG G G G+ G GLPG KG +GDPG+PG+ G G G +G G GE G GP Sbjct: 597 GRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPV 656 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376 G G G+RG G G G G PG PG G G G QG PG DPGA G G +GE Sbjct: 657 GPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPG---DPGAVGPLGPRGER 713 Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436 G GE G PG +G G++G G GP G KG G G PG G PG +G PGERG GTP Sbjct: 714 GNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTP 773 Query: 437 GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE------GPPGSEGAR 490 G +G RG GE G +G G +G G+PG G GP GP G +G+ GPPGS G Sbjct: 774 GPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNP 833 Query: 491 GAPGPAGPPGDPGLMGERGEDG-------PAGNGTEGFPGFPGYPGNRGAPGINGTKGYP 543 G+ G GP G G G +G DG P G +G G PG G G+PG +G G P Sbjct: 834 GSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVP 893 Query: 544 GLKGDEGEAGDPGDDN--NDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 GLKG G G PG G G G GP GP G PG +GPPG Sbjct: 894 GLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPG 942 Score = 285 bits (728), Expect = 2e-76 Identities = 163/355 (45%), Positives = 189/355 (53%), Gaps = 24/355 (6%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314 +RGP G G PG +GE G+ G PGE G AG PG G G G G+KG +G +G +G +G Sbjct: 253 SRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKG 312 Query: 315 PKGYKGEKGKRGIDGVDGVKGEMGYPGLPG---------CKGSPGFDGIQGPPGPKGDPG 365 G G KG+ G G G G +G G+PG G G G+ G PGP G G Sbjct: 313 EVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLG 372 Query: 366 AFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERG 425 G G G PG GEAG G+ GP G +GQ GE GPPG G G G G DG PG +G Sbjct: 373 IPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKG 432 Query: 426 GPGERGPRGTPGTRGPRGDPG---EAGPQGDQGREGPVGVPGDPGEAGP---IGPKGYRG 479 G G G PG+ GP G PG GPQG +G+ G GVPG GEAGP GP G +G Sbjct: 433 PTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQG 492 Query: 480 DEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGT 539 GPPG EG RG G G G PG +GERG G GFPG G PG +GA G G Sbjct: 493 PIGPPGEEGKRGPRGDPGTVGPPGPVGERG-----APGNRGFPGSDGLPGPKGAQGERGP 547 Query: 540 KGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPE---GPQGPPGHQGPPGP 591 G G KG +G+ G PG+ A RG+ G G +GPE GP G PG G PGP Sbjct: 548 VGSSGPKGSQGDPGRPGEPGLPGA-RGLTGNPGVQGPEGKLGPLGAPGEDGRPGP 601 Score = 281 bits (718), Expect = 3e-75 Identities = 155/346 (44%), Positives = 185/346 (53%), Gaps = 17/346 (4%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGD---LGPVGYQGMKGEKGSRGEKGSR 313 GP G G G G+ G PG+PG KGEAG G PG GP+G G +G++G RG+ G+ Sbjct: 453 GPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTV 512 Query: 314 GPKGYKGEKG---KRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370 GP G GE+G RG G DG+ G G G G GS G G QG PG G+PG G + Sbjct: 513 GPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGAR 572 Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGER 430 G G PG G G+ G G G++G+PG PG G +G+ G G PGP G+ G+ G PGE Sbjct: 573 GLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEA 632 Query: 431 GPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGAR 490 G G PG RG G GE GP G G P G+ G+ GE GP GP G++G GPPG G Sbjct: 633 GNAGVPGQRGAPGKDGEVGPSGPVG---PPGLAGERGEQGPPGPTGFQGLPGPPGPPGEG 689 Query: 491 GAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDE 549 G PG G PGDPG +G G G GN G G PG G PG +G G +G G G G Sbjct: 690 GKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPS 749 Query: 550 GEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPDECE 595 G GD G P G++G G RG G GP G +G G E Sbjct: 750 GTPGDTG-------PPGLQGMPGERGIAGTPGPKGDRGGIGEKGAE 788 Score = 279 bits (714), Expect = 8e-75 Identities = 166/370 (44%), Positives = 187/370 (50%), Gaps = 42/370 (11%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GP G RG G +G+RG+ G PG G PG PG +G G G KG GS G G G Sbjct: 390 GPTGARGPEGPQGQRGETGPPGP---VGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSA 446 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGS------PGFDGIQGP---------PGPK 361 G G G +G G G++G+ G PG+PG KG PG GIQGP GP+ Sbjct: 447 GPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPR 506 Query: 362 GDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGE---KGEAGDEGNPGPD 418 GDPG G G GE GA G G PGS G G +G GE GP G KG GD G PG Sbjct: 507 GDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEP 566 Query: 419 GAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYR 478 G PG RG G G +G G GP G PGE G G G +G+ G PG G GPKG Sbjct: 567 GLPGARGLTGNPGVQGPEGKLGPLGAPGE---DGRPGPPGSIGIRGQPGSMGLPGPKGSS 623 Query: 479 GDEGPPGSEGARGAP------------GPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFP 525 GD G PG G G P GP+GP G PGL GERGE GP G G +G PG P Sbjct: 624 GDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPP 683 Query: 526 GYPGNRGAPGINGTKGYPGL---KGDEGEAGDPGD--DNNDIAPRGVKGAKGYRGPEGPQ 580 G PG G PG G G PG G GE G+PG+ + G KG G GP+GP+ Sbjct: 684 GPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPK 743 Query: 581 GPPGHQGPPG 590 G PG G PG Sbjct: 744 GSPGPSGTPG 753 Score = 266 bits (679), Expect = 1e-70 Identities = 161/393 (40%), Positives = 188/393 (47%), Gaps = 57/393 (14%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPG------------------------RPGD 291 RGP G+ G+PG G+ G PG PG G G PG Sbjct: 155 RGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGS 214 Query: 292 LGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGL---PGCKGS 348 +GPVG +G +G +G +G G GP G G+ G G G G +G G PG PG G+ Sbjct: 215 VGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGN 274 Query: 349 PGFDGIQGPPGPKGDPGAFGL------KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGP 402 PG G G PG +G PGA GL +G KG G GE G PGS G +G G G GP Sbjct: 275 PGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGP 334 Query: 403 PGEKGEAGDEGNPGPDGAPGERGG------PGERGPRGTPGTRGPRGDPG---------- 446 G +G G+ G GP GAPG+RG PG GP G PG+ G G+PG Sbjct: 335 LGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGA 394 Query: 447 --EAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGL 504 GPQG +G GP G G PG G IG G G +GP GS G G PG AGPPG PG Sbjct: 395 RGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGP 454 Query: 505 MGERGEDGPAGN-GTEGFPGFPGYPGNRGAP---GINGTKGYPGLKGDEGEAGDPG--DD 558 G G G G G G PGF G G +G P GI G G PG +G G GDPG Sbjct: 455 QGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGP 514 Query: 559 NNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 + RG G +G+ G +G GP G QG GP Sbjct: 515 PGPVGERGAPGNRGFPGSDGLPGPKGAQGERGP 547 Score = 265 bits (676), Expect = 2e-70 Identities = 156/384 (40%), Positives = 179/384 (46%), Gaps = 52/384 (13%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGD----------------------- 291 ++GP G RG G G RG G+ GE G G PG PG Sbjct: 139 SQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGL 198 Query: 292 -------------LGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMG 338 G VG G +G +G +G++G GP G GE G G G G +G G Sbjct: 199 DEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEG 258 Query: 339 YPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPG 398 PG PG G PG +G G G G PGA G G G PG G G G GP G+ G PG Sbjct: 259 PPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPG 318 Query: 399 EPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREG 458 G G G G G GP G PGER G GP+G PG RG G PG+ GP G G G Sbjct: 319 SKGEAGPTGPMGAMGPLGPRGMPGER---GRLGPQGAPGQRGAHGMPGKPGPMGPLGIPG 375 Query: 459 PVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGT 518 G PG+PG G GP G RG EGP G G G PGP G PG PG +G G P G Sbjct: 376 SSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGT--PGAKGP 433 Query: 519 EGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPG--DDNNDIAPRGVKGAKGYRGP 576 G PG G PG+ G PG G +G G +G G+ GDPG + P+G G G +GP Sbjct: 434 TGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGP 493 Query: 577 ---------EGPQGPPGHQGPPGP 591 GP+G PG GPPGP Sbjct: 494 IGPPGEEGKRGPRGDPGTVGPPGP 517 Score = 261 bits (667), Expect = 2e-69 Identities = 152/344 (44%), Positives = 174/344 (50%), Gaps = 48/344 (13%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPG---RPGDLGPVGYQGMKGEKGSRGEKGSR 313 GPPG G PG G G+PG G G GDPG R GD GP G G G+KG GE G Sbjct: 918 GPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQP 977 Query: 314 GPKGYKGEKG---KRGIDGVDGVKGEMGYPGLPGCKGSPG------FDGIQGPPGPKGDP 364 GP G G G +RGI G+ G +GE G PGLPG G+PG G +GPPGP G P Sbjct: 978 GPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPP 1037 Query: 365 GAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGE- 423 G+ G GE G G G G PG G G+ G G+PGP G G G G PGP GAPG+ Sbjct: 1038 GSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDA 1097 Query: 424 --RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE 481 RG PG RGP G PG G RG PG GP+GD+G G G G G G G +G G Sbjct: 1098 GQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPP 1157 Query: 482 GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKG 541 GP G +G+ G PGP GP G PG +G G++G PG G G PG+ G+ G Sbjct: 1158 GPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGN-----------PGPLGPIGPPGVRGSVG 1206 Query: 542 YPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGH 585 G +G GE GP GP GPPGH Sbjct: 1207 EAGPEGPPGEP----------------------GPPGPPGPPGH 1228 Score = 259 bits (662), Expect = 9e-69 Identities = 157/371 (42%), Positives = 181/371 (48%), Gaps = 39/371 (10%) Query: 247 CCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGS 306 CC C G G +G++G+PGL G GRPG GP G QG +GE Sbjct: 92 CCPV-CSQTPGGGNTNFGRGRKGQKGEPGLVPVV--TGIRGRPGPAGPPGSQGPRGE--- 145 Query: 307 RGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD--- 363 RGPKG G +G +GIDG GV G+ G PG PG PG DG+ P + Sbjct: 146 ------RGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLD 199 Query: 364 ------------PGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD 411 PG+ G G +G G G+ G G +GP G+ G PG GP G +G G Sbjct: 200 EKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGP 259 Query: 412 EGNPGPDGAPGERGGPGERGPRGTPGTR---GPRGDPGEAGPQGDQGREGP---VGVPGD 465 G PG DG PG G PGE G G+PG R G G PG G +G +G EGP VG PG Sbjct: 260 PGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGS 319 Query: 466 PGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGF 524 GEAGP GP G G GP G G RG GP G PG G G G+ GP G G G GF Sbjct: 320 KGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGF 379 Query: 525 PGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNND-----IAPRGVKGAKGYRGPEGP 579 PG PG +G G G +G G +G GE G PG + I G GAKG G G Sbjct: 380 PGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGT 439 Query: 580 QGPPGHQGPPG 590 GPPG GPPG Sbjct: 440 SGPPGSAGPPG 450 Score = 145 bits (366), Expect = 2e-34 Identities = 79/167 (47%), Positives = 91/167 (54%), Gaps = 12/167 (7%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RG PG G PG +G G PG G G+AG G PG GP+G G G++G G +G RG Sbjct: 1070 RGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGD 1129 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375 KG G++G RG G G G G PG PG G G GI GP GP+G PG G G++G Sbjct: 1130 KGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGN 1189 Query: 376 PGADGEAGRPG---SSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDG 419 PG G G PG S G +G EG PGEPGPP G PGP G Sbjct: 1190 PGPLGPIGPPGVRGSVGEAGPEGPPGEPGPP---------GPPGPPG 1227 Score = 133 bits (335), Expect = 8e-31 Identities = 74/161 (45%), Positives = 88/161 (54%), Gaps = 18/161 (11%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312 Q A G PG G PG G+RG PG +G G PGR G G G QG +G+KG G++G Sbjct: 1082 QGAPGTPGPVGAPGDAGQRGD---PGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGD 1138 Query: 313 RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372 RG KG++G G +G+ PG PG G G GI GP GP+G PG G G+ Sbjct: 1139 RGQKGHRGFTGLQGL------------PGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGK 1186 Query: 373 KGEPGADGEAGRP---GSSGPSGDEGQPGEPGPPGEKGEAG 410 +G PG G G P GS G +G EG PGEPGPPG G G Sbjct: 1187 EGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPG 1227 Score = 66.6 bits (161), Expect = 1e-10 Identities = 43/127 (33%), Positives = 52/127 (40%), Gaps = 30/127 (23%) Query: 466 PGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFP 525 PGE P+ + PG G G G+PGL+ P G G PG Sbjct: 89 PGECCPVCSQ-------TPGGGNTNFGRGRKGQKGEPGLV-------PVVTGIRGRPGPA 134 Query: 526 GYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGH 585 G PG++G G G KG PG +G P+G+ G G G G GPPGH Sbjct: 135 GPPGSQGPRGERGPKGRPGPRG----------------PQGIDGEPGVPGQPGAPGPPGH 178 Query: 586 QGPPGPD 592 PGPD Sbjct: 179 PSHPGPD 185 >gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo sapiens] Length = 1650 Score = 305 bits (781), Expect = 1e-82 Identities = 182/428 (42%), Positives = 209/428 (48%), Gaps = 98/428 (22%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GPPG+ G+ G +GE G PG G KG G+ G PG GP+G G G G+ GE G+RGP+ Sbjct: 989 GPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQ 1048 Query: 317 GYKGEKGK---------------RGIDGVDGVKGE------MGYPGLPGCKGSPGFDGIQ 355 G+ G KG +G+ G G KGE MG PG PG +G G +G Sbjct: 1049 GHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGAD 1108 Query: 356 GPPGPKGDPGAFGLKGEKGEPGADGE---AGRPGSSGP------SGDEGQPGEPGPPGEK 406 GP GP G G G GEKGEPG G G PG GP G+ GQPGEPGPPG K Sbjct: 1109 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK 1168 Query: 407 GEAGDE---GNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEA------------GPQ 451 G GD+ GNPGP G PG+ G PGE GPRG G +G RG+ GE GP Sbjct: 1169 GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPP 1228 Query: 452 GDQGREGPVGVPGD------------------PGEAGPIGPKGYRGDEGP---------- 483 G G+ GP G PG PG+ GP+GP G G GP Sbjct: 1229 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1288 Query: 484 -----PGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN----------GTEGFPGFPGYP 528 PG+ G G PGP GPPG PGL G+ G G G+ G +G G G P Sbjct: 1289 GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1348 Query: 529 GNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGP------QGP 582 G +G+PG G G PG G G G PG P G KGAKG GP GP QGP Sbjct: 1349 GPQGSPGQKGEMGIPGASGPIGPGGPPGLP----GPAGPKGAKGATGPGGPKGEKGVQGP 1404 Query: 583 PGHQGPPG 590 PGH GPPG Sbjct: 1405 PGHPGPPG 1412 Score = 297 bits (760), Expect = 4e-80 Identities = 164/341 (48%), Positives = 189/341 (55%), Gaps = 20/341 (5%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G PG RG G +G RG G GEKGE G PG GD+G G +G G GSRGE G GPK Sbjct: 629 GYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPK 688 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376 G G G G G+ G KG++G PGLPG + G QGP G G PG G GEKG Sbjct: 689 GRTGPTGDPGPPGLMGEKGKLGVPGLPG------YPGRQGPKGSLGFPGFPGASGEKGAR 742 Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436 G G++G G GP+G GQ G G G+ G G G GP G PGERG PG +GP G P Sbjct: 743 GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 802 Query: 437 GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPA 496 G +GP G PG+ G G G+ G VG G G GP G G +G G G G RG PGP Sbjct: 803 GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 862 Query: 497 GPPGDPGLMGERGEDG-------PAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDE 549 GPPG+ GL G G++G P G +G G G+PG RG P GT G PGLKG+E Sbjct: 863 GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLP---GTAGGPGLKGNE 919 Query: 550 GEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G +G PG + G +GA G GP GP G PG QGPPG Sbjct: 920 GPSGPPGPAGSP----GERGAAGSGGPIGPPGRPGPQGPPG 956 Score = 292 bits (748), Expect = 1e-78 Identities = 166/370 (44%), Positives = 199/370 (53%), Gaps = 38/370 (10%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312 Q RGP GL G PG G RG+ G G +G GDPG GD G G G+ GEKG RG+ G+ Sbjct: 433 QGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGA 492 Query: 313 RGPKGYKGEKGKRGID------------GVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP 360 +G G GE G+RG D G G+ G G PG+PG G G DG QGP G Sbjct: 493 QGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGS 552 Query: 361 KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA 420 G G G G++G PG G G G+ GP G++G G+PG PG G G G+PG +G Sbjct: 553 LGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGP 612 Query: 421 PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480 PG +G G GP+G G GPRG G G +G +G +G G G PG G IG KG RG+ Sbjct: 613 PGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGE 672 Query: 481 EGPPGS------EGARGAPGPAGPPGDPGLMGERGEDGPAG----------NGTEGFPGF 524 G PGS EG +G GP G PG PGLMGE+G+ G G G+ GFPGF Sbjct: 673 VGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGF 732 Query: 525 PGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGV---KGAKGYRGPEGPQG 581 PG G +GA G++G G G +G G G G PRG GAKG G +GP G Sbjct: 733 PGASGEKGARGLSGKSGPRGERGPTGPRGQRG-------PRGATGKSGAKGTSGGDGPHG 785 Query: 582 PPGHQGPPGP 591 PPG +G PGP Sbjct: 786 PPGERGLPGP 795 Score = 291 bits (745), Expect = 2e-78 Identities = 173/408 (42%), Positives = 205/408 (50%), Gaps = 72/408 (17%) Query: 257 GPPGLRGDPGFEGERGKPGLPGE---KGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG-- 311 GPPGL G+ G G G PG PG KG G PG PG G G +G+ G+ G RGE+G Sbjct: 698 GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 757 Query: 312 ----SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAF 367 RGP+G G+ G +G G DG G G GLPG +G GF G +GPPGP G G Sbjct: 758 GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLP 817 Query: 368 GLKGEKGEPGADGEAGRPG------------SSGPSGDEGQPGEPGPPGEKG------EA 409 G G++GE G G+ G PG +GP G+ G PG PGPPGE+G + Sbjct: 818 GHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKE 877 Query: 410 GDEGNPGPDGAPGE------RGGPGER---------------------GPRGTPGTRGPR 442 G +G+PGP GAPG+ RG PGER GP G+PG RG Sbjct: 878 GTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAA 937 Query: 443 GDPGEAGPQGDQGREGPVGVPGD---PGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPP 499 G G GP G G +GP G G+ PGE GPIGP G G +GP G G G PG AG Sbjct: 938 GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGED 997 Query: 500 GDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDD 558 GD G +G+ G+ G GN G G PG PG G G PG G G PG +G +G G GD+ Sbjct: 998 GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1057 Query: 559 NND--------------IAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592 P G KG G GP GP GPPG +GP GP+ Sbjct: 1058 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPN 1105 Score = 281 bits (719), Expect = 2e-75 Identities = 158/346 (45%), Positives = 182/346 (52%), Gaps = 20/346 (5%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQG------MKGEKGSRGEK 310 GPPG G G G G+ G+PGEKG G GR G GPVG G + GE G +GE Sbjct: 944 GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 1003 Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370 G G KG KG KG+ G G G G +G PG G G PG G QG G KGD G G Sbjct: 1004 GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFN 1063 Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPG---ERGGP 427 G G G G G G G +GD G G PGPPG +G AG G GP G PG G P Sbjct: 1064 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPP 1123 Query: 428 GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487 GE+G G G+ G +G+PG GP+G++G +G G PG+P GP GPKG GD+GP G+ Sbjct: 1124 GEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEP---GPPGPKGPTGDDGPKGNP 1180 Query: 488 GARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGTKGYPGLK 546 G G PG GPPG+ G G+ G G G +G G PG PG G G PG G +G G Sbjct: 1181 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1240 Query: 547 GDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592 G EG G G +G GA G G GP GP G G PGPD Sbjct: 1241 GSEGRQGGKG-------AKGDPGAIGAPGKTGPVGPAGPAGKPGPD 1279 Score = 279 bits (714), Expect = 8e-75 Identities = 164/350 (46%), Positives = 183/350 (52%), Gaps = 26/350 (7%) Query: 257 GPPGLRGDPGFEGERGKPGL---PGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSR 313 GPPG RG PG +G G PG PG G+ G PG PG G VG+QG G G G G + Sbjct: 785 GPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ 844 Query: 314 GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373 G G G G+RG G G GE G LPG G G G GPPG G G GL+G Sbjct: 845 GAAGETGPMGERGHPGPPGPPGEQG---LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFP 901 Query: 374 GEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD------EGNPGPDGAP---GER 424 GE G G AG PG G G G PG G PGE+G AG G PGP G P GE+ Sbjct: 902 GERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEK 961 Query: 425 GGPGER---GPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE 481 G PGE+ GP G G +GP G PG AGP G G +G G GDPG+ G G KG G Sbjct: 962 GVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPP 1021 Query: 482 GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTK 540 GPPG G G PG AG G+PG G +G G G+ GT GF G PG G +G PG +G K Sbjct: 1022 GPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEK 1081 Query: 541 GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G G G G G PG PRG G G GP+GP G G+ GPPG Sbjct: 1082 GETGDVGPMGPPGPPG-------PRGPAGPNGADGPQGPPGGVGNLGPPG 1124 Score = 279 bits (713), Expect = 1e-74 Identities = 161/377 (42%), Positives = 189/377 (50%), Gaps = 51/377 (13%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGE------ 309 RG PG G PG +G G G G KG+ G PG PG GP G +G GE+G G Sbjct: 856 RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGL 915 Query: 310 KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGL 369 KG+ GP G G G G G G G +G PG PG +G PG G +G PG KG G G Sbjct: 916 KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGR 975 Query: 370 KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGE 429 G +G G G AG PG +G GD+G+ G+PG G KG G+ G PGP G G G PG Sbjct: 976 DGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1035 Query: 430 RGPRGTPGTRGPRGD------------------------PGEAGPQGDQGREGPVGVPGD 465 G G PG RGP+G PG +G +G+ G GP+G PG Sbjct: 1036 AGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP 1095 Query: 466 PGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGD---PGLMGE---------RGEDGP 513 PG GP GP G G +GPPG G G PG G PG+ PG+ GE RGE G Sbjct: 1096 PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGE 1155 Query: 514 AGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573 +G PG PG PG +G G +G KG PG G G+ G PG+ PRG GAKG Sbjct: 1156 SGQ-----PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEG----GPRGQDGAKGD 1206 Query: 574 RGPEGPQGPPGHQGPPG 590 RG +G G PG GP G Sbjct: 1207 RGEDGEPGQPGSPGPTG 1223 Score = 277 bits (709), Expect = 3e-74 Identities = 165/378 (43%), Positives = 194/378 (51%), Gaps = 45/378 (11%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP---VGYQGMKGEKGSRGE 309 Q G PG +G PG G+ G PG PG++GE G G+ G GP VG QG GE G GE Sbjct: 796 QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 855 Query: 310 KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPG---FDGIQGPPGPKGDPGA 366 +G GP G GE+G G G +G KG+ G PG PG G G F G +G PG G PG Sbjct: 856 RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGL 915 Query: 367 FGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGP------------PGEKGEAGDEGN 414 G +G G PG G G G++G G G PG PGP PGEKG G G Sbjct: 916 KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGR 975 Query: 415 ---------PGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVP-- 463 PGP G PG G G++G G PG +G +G+ GE GP G G GPVG P Sbjct: 976 DGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1035 Query: 464 ----GDPGEAGPIGPKGYRGDE------GPPGSEGARGAPGPAGPPGDPGLMGERGEDGP 513 G+PG GP G G +GDE GPPG G +G PGP+G G+ G +G G GP Sbjct: 1036 AGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP 1095 Query: 514 AGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573 G G G G G +G PG G G PG KG+ GE+G PG GVKG +G Sbjct: 1096 P--GPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEP----GVKGPRGE 1149 Query: 574 RGPEGPQGPPGHQGPPGP 591 RG +G G PG GPPGP Sbjct: 1150 RGEKGESGQPGEPGPPGP 1167 Score = 277 bits (708), Expect = 4e-74 Identities = 163/387 (42%), Positives = 190/387 (49%), Gaps = 55/387 (14%) Query: 256 RGPPGLRGDPGFEGERGKPG-------------------------------------LPG 278 RGPPG G PG +G G PG L G Sbjct: 342 RGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRG 401 Query: 279 EKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMG 338 G G GRPG LG G G+KGE G G +G RGP+G G GK G G G G G Sbjct: 402 PPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARG 461 Query: 339 YPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGE---------AGRPGSSG 389 PG PG KG GFDG+ G PG KG G G +G G PG DGE G PG SG Sbjct: 462 MPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESG 521 Query: 390 PSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAG 449 P G G G PG PG G G +G GP G+ G +G PG G +GTPGT+G G G G Sbjct: 522 PRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIG 581 Query: 450 PQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERG 509 P G++G +G G+PG PG GP G+ G EGPPG++G +G GP GP G PG G +G Sbjct: 582 PHGEKGPQGKPGLPGMPGSD---GPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKG 638 Query: 510 EDGPAG----NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPG--DDNNDIA 563 DG G G +G GFPG+ G+ G G G G PG +G++G G G D Sbjct: 639 VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG 698 Query: 564 PRGVKGAKGYRGPEGPQGPPGHQGPPG 590 P G+ G KG G G G PG QGP G Sbjct: 699 PPGLMGEKGKLGVPGLPGYPGRQGPKG 725 Score = 272 bits (696), Expect = 1e-72 Identities = 157/358 (43%), Positives = 186/358 (51%), Gaps = 25/358 (6%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RG G RG G G +G G G G G+ G PG GP G+ G KG G G+ G G Sbjct: 760 RGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGH 819 Query: 316 KGYKGE---KGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372 G +GE +GK G G GV G G G G G G G GPPG +G PG G +G Sbjct: 820 PGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 879 Query: 373 KGEPGADGEAGRPGSSGP---SGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGG--- 426 KG+PG G G+ G +G G+ G PG G PG KG G G PGP G+PGERG Sbjct: 880 KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 939 Query: 427 ------PGERGPRGTPGTRGPRGDPGEAGPQGDQGR---EGPVGVPGDPGEAGPIGPKGY 477 PG GP+G PG G +G PGE GP G GR +GPVG+PG G G G G Sbjct: 940 GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGD 999 Query: 478 RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGIN 537 +G+ G PG +G +G G GPPG PG +G G+ G A G +G PG G G+ GA G Sbjct: 1000 KGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAA--GADGEPGARGPQGHFGAKGDE 1057 Query: 538 GTKGYPGLKGDEGEAGDPG-----DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 GT+G+ G G G G PG + D+ P G G G RGP GP G G QGPPG Sbjct: 1058 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG 1115 Score = 264 bits (674), Expect = 4e-70 Identities = 166/390 (42%), Positives = 188/390 (48%), Gaps = 58/390 (14%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK------ 310 GPPG G G G PG+ G G GDPG G G G G G G G Sbjct: 313 GPPGPEGPAGLIGP---PGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFR 369 Query: 311 -----GSRGPKGYKGE--------------KGKRGIDGVDGVKGEMGYPGLPGCKGSPGF 351 G +GP E +G G G G G +G PG PG KG G Sbjct: 370 FGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGD 429 Query: 352 DGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD 411 G QGP GP+G G G G +G GADG G PG G GD G G PG PGEKG GD Sbjct: 430 LGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGD 489 Query: 412 ---EGNPGPDGAPGERGGPGERGPRGTPGTRGPR------GDPGEAGPQGDQGREGPVGV 462 +G PGP G GERG GE GPRG PG GPR G PG GP G +G +GP G Sbjct: 490 TGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGP 549 Query: 463 PGD---PGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GT 518 G GE GP G +G G +G PG +GA G G GP G PGL G G DGP G+ G Sbjct: 550 KGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGK 609 Query: 519 EGFPGFP------------GYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNN-----D 561 EG PG GYPG RG G++G +G G KG++GE G PG + D Sbjct: 610 EGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGD 669 Query: 562 IAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 GV G++G GPEGP+G G G PGP Sbjct: 670 RGEVGVPGSRGEDGPEGPKGRTGPTGDPGP 699 Score = 243 bits (621), Expect = 5e-64 Identities = 130/276 (47%), Positives = 155/276 (56%), Gaps = 9/276 (3%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 +GP G RG+ G G+ G+PG PG KG GD G G+ GPVG+ G G G G +G G Sbjct: 1144 KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGA 1203 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKG---SPGFDGIQGPPGPKGDPGAFGLKGE 372 KG +GE G+ G G G GE G PG G +G SPG +G QG G KGDPGA G G+ Sbjct: 1204 KGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGK 1263 Query: 373 KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGP 432 G G G AG+PG G G G G+ G PG G+AG G GP G PG RG G +G Sbjct: 1264 TGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1323 Query: 433 RGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGD------PGEAGPIGPKGYRGDEGPPGS 486 +G PG G G PGE G +GD+G GP G PG PG +GPIGP G G GP G Sbjct: 1324 KGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGP 1383 Query: 487 EGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFP 522 +GA+GA GP GP G+ G+ G G GP G + P Sbjct: 1384 KGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1419 Score = 201 bits (510), Expect = 4e-51 Identities = 136/370 (36%), Positives = 164/370 (44%), Gaps = 108/370 (29%) Query: 309 EKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK------- 361 E+ + GP+G KGEKG+ + PG+ ++GPPGP+ Sbjct: 286 EEAAHGPRGLKGEKGEPAVLE----------PGML----------VEGPPGPEGPAGLIG 325 Query: 362 -----------GDPGAFGLKGEKGEPGADGEAGRPGSS---------------------- 388 GDPG G G G PG+DG G PG+S Sbjct: 326 PPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQE 385 Query: 389 ------------------GPSGDEGQP---GEPGPPGEKGEAGDEGNPGPDGAPGERGGP 427 GP G G+P G+PG PG KGE+GD G GP G G G P Sbjct: 386 AQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPP 445 Query: 428 GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGE---------AGPIGPKGYR 478 G+ G RG G G RG PG+ G +GD+G +G G+PG+ G GP G G R Sbjct: 446 GKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGER 505 Query: 479 GDEGP------PGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-------NGTEGFPGFP 525 GD+G PG G RG GP GPPG PG G RG DGP G G G PG Sbjct: 506 GDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQ 565 Query: 526 GYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAP-----RGVKGAKGYRGPEGPQ 580 G PG +G PG G G G KG +G+ G PG +D P G G KG +GP GPQ Sbjct: 566 GTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQ 625 Query: 581 GPPGHQGPPG 590 GP G+ GP G Sbjct: 626 GPLGYPGPRG 635 Score = 199 bits (505), Expect = 1e-50 Identities = 119/281 (42%), Positives = 140/281 (49%), Gaps = 20/281 (7%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGD---PGRPGDLGPVGYQGMKGEKGSRGEKGSR 313 GP G GDPG GE G G G KG+ G+ PG+PG GP G G G G RG GS Sbjct: 1181 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1240 Query: 314 GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373 G +G +G KG +G G G G+ G G G G PG DG++G PG G G G G+ Sbjct: 1241 GSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQA 1300 Query: 374 GEPGADGEAGRPGSSGPSGDEGQPGEP------GPPGEKGEAGDEGNPGPDGAPGERGGP 427 G PG G G PG G +G +G+ G P GPPGE+GE GD G PGP G+PG++G Sbjct: 1301 GPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEM 1360 Query: 428 GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487 G G G G GP G PG AGP+G +G GP GP G KG +G G PG Sbjct: 1361 GIPGASGPIGPGGPPGLPGPAGPKGAKGATGP---------GGPKGEKGVQGPPGHPGPP 1411 Query: 488 GARGAPGPAGPPGDP--GLMGERGEDGPAGNGTEGFPGFPG 526 G P P P + G R T G PG PG Sbjct: 1412 GEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1452 Score = 186 bits (472), Expect = 1e-46 Identities = 114/269 (42%), Positives = 132/269 (49%), Gaps = 27/269 (10%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS--- 312 RG G +GD G +GE G+PG PG GE G PG G GP G G +G +G +G KG Sbjct: 1198 RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGA 1257 Query: 313 ------RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366 GP G G GK G DG+ G+ G +G G PG G G GP GP G PG Sbjct: 1258 IGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAG---PPGPVGPPGLPGL 1314 Query: 367 ---FGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGE 423 G KGEKG PG G G PG G GD G PG G PG+KGE G G GP G G Sbjct: 1315 RGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP 1374 Query: 424 RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGP-----KGYR 478 G PG GP+G G GP GP+G++G +GP G PG PGE P K R Sbjct: 1375 PGLPGPAGPKGAKGATGP------GGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRR 1428 Query: 479 GDEGPPGSEGARGAPGPAGPPGDPGLMGE 507 +G + P G PG PG + E Sbjct: 1429 SVDGSRLMQEDEAIP-TGGAPGSPGGLEE 1456 Score = 182 bits (461), Expect = 2e-45 Identities = 115/280 (41%), Positives = 131/280 (46%), Gaps = 69/280 (24%) Query: 357 PPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPG 416 PP + G GLKGEKGEP PG EG PG GP G G G +GNPG Sbjct: 283 PPLEEAAHGPRGLKGEKGEPAVL----EPGMLV----EGPPGPEGPAGLIGPPGIQGNPG 334 Query: 417 PDGAPGERGGPGERGPRGTPGTRGPRGDP------------------------------- 445 P G PGERG PG G G+ G GP G Sbjct: 335 PVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQ 394 Query: 446 ------GEAGPQGDQGREGPVGVPGDP------GEAGPIGPKGYRGDEGPPGSEGAR--- 490 G GP G GR GP+G PG P G+ GP GP+G +G GPPG G R Sbjct: 395 ARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRA 454 Query: 491 GAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEG 550 GA G G PGDPG+ G+R GF G PG PG +G G G +G PG G++G Sbjct: 455 GADGARGMPGDPGVKGDR-----------GFDGLPGLPGEKGHRGDTGAQGLPGPPGEDG 503 Query: 551 EAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 E GD G +I PRG+ G G RG GP+GPPG GPPG Sbjct: 504 ERGDDG----EIGPRGLPGESGPRGLLGPKGPPGIPGPPG 539 Score = 31.2 bits (69), Expect = 5.2 Identities = 13/25 (52%), Positives = 16/25 (64%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGE 279 A GP G +G+ G +G G PG PGE Sbjct: 1389 ATGPGGPKGEKGVQGPPGHPGPPGE 1413 >gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo sapiens] Length = 1629 Score = 305 bits (781), Expect = 1e-82 Identities = 182/428 (42%), Positives = 209/428 (48%), Gaps = 98/428 (22%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GPPG+ G+ G +GE G PG G KG G+ G PG GP+G G G G+ GE G+RGP+ Sbjct: 968 GPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQ 1027 Query: 317 GYKGEKGK---------------RGIDGVDGVKGE------MGYPGLPGCKGSPGFDGIQ 355 G+ G KG +G+ G G KGE MG PG PG +G G +G Sbjct: 1028 GHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGAD 1087 Query: 356 GPPGPKGDPGAFGLKGEKGEPGADGE---AGRPGSSGP------SGDEGQPGEPGPPGEK 406 GP GP G G G GEKGEPG G G PG GP G+ GQPGEPGPPG K Sbjct: 1088 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK 1147 Query: 407 GEAGDE---GNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEA------------GPQ 451 G GD+ GNPGP G PG+ G PGE GPRG G +G RG+ GE GP Sbjct: 1148 GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPP 1207 Query: 452 GDQGREGPVGVPGD------------------PGEAGPIGPKGYRGDEGP---------- 483 G G+ GP G PG PG+ GP+GP G G GP Sbjct: 1208 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1267 Query: 484 -----PGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN----------GTEGFPGFPGYP 528 PG+ G G PGP GPPG PGL G+ G G G+ G +G G G P Sbjct: 1268 GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1327 Query: 529 GNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGP------QGP 582 G +G+PG G G PG G G G PG P G KGAKG GP GP QGP Sbjct: 1328 GPQGSPGQKGEMGIPGASGPIGPGGPPGLP----GPAGPKGAKGATGPGGPKGEKGVQGP 1383 Query: 583 PGHQGPPG 590 PGH GPPG Sbjct: 1384 PGHPGPPG 1391 Score = 297 bits (760), Expect = 4e-80 Identities = 164/341 (48%), Positives = 189/341 (55%), Gaps = 20/341 (5%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G PG RG G +G RG G GEKGE G PG GD+G G +G G GSRGE G GPK Sbjct: 608 GYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPK 667 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376 G G G G G+ G KG++G PGLPG + G QGP G G PG G GEKG Sbjct: 668 GRTGPTGDPGPPGLMGEKGKLGVPGLPG------YPGRQGPKGSLGFPGFPGASGEKGAR 721 Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436 G G++G G GP+G GQ G G G+ G G G GP G PGERG PG +GP G P Sbjct: 722 GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 781 Query: 437 GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPA 496 G +GP G PG+ G G G+ G VG G G GP G G +G G G G RG PGP Sbjct: 782 GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 841 Query: 497 GPPGDPGLMGERGEDG-------PAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDE 549 GPPG+ GL G G++G P G +G G G+PG RG P GT G PGLKG+E Sbjct: 842 GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLP---GTAGGPGLKGNE 898 Query: 550 GEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G +G PG + G +GA G GP GP G PG QGPPG Sbjct: 899 GPSGPPGPAGSP----GERGAAGSGGPIGPPGRPGPQGPPG 935 Score = 292 bits (748), Expect = 1e-78 Identities = 166/370 (44%), Positives = 199/370 (53%), Gaps = 38/370 (10%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312 Q RGP GL G PG G RG+ G G +G GDPG GD G G G+ GEKG RG+ G+ Sbjct: 412 QGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGA 471 Query: 313 RGPKGYKGEKGKRGID------------GVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP 360 +G G GE G+RG D G G+ G G PG+PG G G DG QGP G Sbjct: 472 QGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGS 531 Query: 361 KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA 420 G G G G++G PG G G G+ GP G++G G+PG PG G G G+PG +G Sbjct: 532 LGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGP 591 Query: 421 PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480 PG +G G GP+G G GPRG G G +G +G +G G G PG G IG KG RG+ Sbjct: 592 PGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGE 651 Query: 481 EGPPGS------EGARGAPGPAGPPGDPGLMGERGEDGPAG----------NGTEGFPGF 524 G PGS EG +G GP G PG PGLMGE+G+ G G G+ GFPGF Sbjct: 652 VGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGF 711 Query: 525 PGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGV---KGAKGYRGPEGPQG 581 PG G +GA G++G G G +G G G G PRG GAKG G +GP G Sbjct: 712 PGASGEKGARGLSGKSGPRGERGPTGPRGQRG-------PRGATGKSGAKGTSGGDGPHG 764 Query: 582 PPGHQGPPGP 591 PPG +G PGP Sbjct: 765 PPGERGLPGP 774 Score = 291 bits (745), Expect = 2e-78 Identities = 173/408 (42%), Positives = 205/408 (50%), Gaps = 72/408 (17%) Query: 257 GPPGLRGDPGFEGERGKPGLPGE---KGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG-- 311 GPPGL G+ G G G PG PG KG G PG PG G G +G+ G+ G RGE+G Sbjct: 677 GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 736 Query: 312 ----SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAF 367 RGP+G G+ G +G G DG G G GLPG +G GF G +GPPGP G G Sbjct: 737 GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLP 796 Query: 368 GLKGEKGEPGADGEAGRPG------------SSGPSGDEGQPGEPGPPGEKG------EA 409 G G++GE G G+ G PG +GP G+ G PG PGPPGE+G + Sbjct: 797 GHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKE 856 Query: 410 GDEGNPGPDGAPGE------RGGPGER---------------------GPRGTPGTRGPR 442 G +G+PGP GAPG+ RG PGER GP G+PG RG Sbjct: 857 GTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAA 916 Query: 443 GDPGEAGPQGDQGREGPVGVPGD---PGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPP 499 G G GP G G +GP G G+ PGE GPIGP G G +GP G G G PG AG Sbjct: 917 GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGED 976 Query: 500 GDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDD 558 GD G +G+ G+ G GN G G PG PG G G PG G G PG +G +G G GD+ Sbjct: 977 GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1036 Query: 559 NND--------------IAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592 P G KG G GP GP GPPG +GP GP+ Sbjct: 1037 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPN 1084 Score = 281 bits (719), Expect = 2e-75 Identities = 158/346 (45%), Positives = 182/346 (52%), Gaps = 20/346 (5%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQG------MKGEKGSRGEK 310 GPPG G G G G+ G+PGEKG G GR G GPVG G + GE G +GE Sbjct: 923 GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 982 Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370 G G KG KG KG+ G G G G +G PG G G PG G QG G KGD G G Sbjct: 983 GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFN 1042 Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPG---ERGGP 427 G G G G G G G +GD G G PGPPG +G AG G GP G PG G P Sbjct: 1043 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPP 1102 Query: 428 GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487 GE+G G G+ G +G+PG GP+G++G +G G PG+P GP GPKG GD+GP G+ Sbjct: 1103 GEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEP---GPPGPKGPTGDDGPKGNP 1159 Query: 488 GARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGTKGYPGLK 546 G G PG GPPG+ G G+ G G G +G G PG PG G G PG G +G G Sbjct: 1160 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1219 Query: 547 GDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592 G EG G G +G GA G G GP GP G G PGPD Sbjct: 1220 GSEGRQGGKG-------AKGDPGAIGAPGKTGPVGPAGPAGKPGPD 1258 Score = 279 bits (714), Expect = 8e-75 Identities = 164/350 (46%), Positives = 183/350 (52%), Gaps = 26/350 (7%) Query: 257 GPPGLRGDPGFEGERGKPGL---PGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSR 313 GPPG RG PG +G G PG PG G+ G PG PG G VG+QG G G G G + Sbjct: 764 GPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ 823 Query: 314 GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373 G G G G+RG G G GE G LPG G G G GPPG G G GL+G Sbjct: 824 GAAGETGPMGERGHPGPPGPPGEQG---LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFP 880 Query: 374 GEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD------EGNPGPDGAP---GER 424 GE G G AG PG G G G PG G PGE+G AG G PGP G P GE+ Sbjct: 881 GERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEK 940 Query: 425 GGPGER---GPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE 481 G PGE+ GP G G +GP G PG AGP G G +G G GDPG+ G G KG G Sbjct: 941 GVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPP 1000 Query: 482 GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTK 540 GPPG G G PG AG G+PG G +G G G+ GT GF G PG G +G PG +G K Sbjct: 1001 GPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEK 1060 Query: 541 GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G G G G G PG PRG G G GP+GP G G+ GPPG Sbjct: 1061 GETGDVGPMGPPGPPG-------PRGPAGPNGADGPQGPPGGVGNLGPPG 1103 Score = 279 bits (713), Expect = 1e-74 Identities = 161/377 (42%), Positives = 189/377 (50%), Gaps = 51/377 (13%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGE------ 309 RG PG G PG +G G G G KG+ G PG PG GP G +G GE+G G Sbjct: 835 RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGL 894 Query: 310 KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGL 369 KG+ GP G G G G G G G +G PG PG +G PG G +G PG KG G G Sbjct: 895 KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGR 954 Query: 370 KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGE 429 G +G G G AG PG +G GD+G+ G+PG G KG G+ G PGP G G G PG Sbjct: 955 DGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1014 Query: 430 RGPRGTPGTRGPRGD------------------------PGEAGPQGDQGREGPVGVPGD 465 G G PG RGP+G PG +G +G+ G GP+G PG Sbjct: 1015 AGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP 1074 Query: 466 PGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGD---PGLMGE---------RGEDGP 513 PG GP GP G G +GPPG G G PG G PG+ PG+ GE RGE G Sbjct: 1075 PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGE 1134 Query: 514 AGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573 +G PG PG PG +G G +G KG PG G G+ G PG+ PRG GAKG Sbjct: 1135 SGQ-----PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEG----GPRGQDGAKGD 1185 Query: 574 RGPEGPQGPPGHQGPPG 590 RG +G G PG GP G Sbjct: 1186 RGEDGEPGQPGSPGPTG 1202 Score = 277 bits (709), Expect = 3e-74 Identities = 165/378 (43%), Positives = 194/378 (51%), Gaps = 45/378 (11%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP---VGYQGMKGEKGSRGE 309 Q G PG +G PG G+ G PG PG++GE G G+ G GP VG QG GE G GE Sbjct: 775 QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 834 Query: 310 KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPG---FDGIQGPPGPKGDPGA 366 +G GP G GE+G G G +G KG+ G PG PG G G F G +G PG G PG Sbjct: 835 RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGL 894 Query: 367 FGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGP------------PGEKGEAGDEGN 414 G +G G PG G G G++G G G PG PGP PGEKG G G Sbjct: 895 KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGR 954 Query: 415 ---------PGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVP-- 463 PGP G PG G G++G G PG +G +G+ GE GP G G GPVG P Sbjct: 955 DGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1014 Query: 464 ----GDPGEAGPIGPKGYRGDE------GPPGSEGARGAPGPAGPPGDPGLMGERGEDGP 513 G+PG GP G G +GDE GPPG G +G PGP+G G+ G +G G GP Sbjct: 1015 AGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP 1074 Query: 514 AGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573 G G G G G +G PG G G PG KG+ GE+G PG GVKG +G Sbjct: 1075 P--GPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEP----GVKGPRGE 1128 Query: 574 RGPEGPQGPPGHQGPPGP 591 RG +G G PG GPPGP Sbjct: 1129 RGEKGESGQPGEPGPPGP 1146 Score = 277 bits (708), Expect = 4e-74 Identities = 163/387 (42%), Positives = 190/387 (49%), Gaps = 55/387 (14%) Query: 256 RGPPGLRGDPGFEGERGKPG-------------------------------------LPG 278 RGPPG G PG +G G PG L G Sbjct: 321 RGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRG 380 Query: 279 EKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMG 338 G G GRPG LG G G+KGE G G +G RGP+G G GK G G G G G Sbjct: 381 PPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARG 440 Query: 339 YPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGE---------AGRPGSSG 389 PG PG KG GFDG+ G PG KG G G +G G PG DGE G PG SG Sbjct: 441 MPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESG 500 Query: 390 PSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAG 449 P G G G PG PG G G +G GP G+ G +G PG G +GTPGT+G G G G Sbjct: 501 PRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIG 560 Query: 450 PQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERG 509 P G++G +G G+PG PG GP G+ G EGPPG++G +G GP GP G PG G +G Sbjct: 561 PHGEKGPQGKPGLPGMPGSD---GPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKG 617 Query: 510 EDGPAG----NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPG--DDNNDIA 563 DG G G +G GFPG+ G+ G G G G PG +G++G G G D Sbjct: 618 VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG 677 Query: 564 PRGVKGAKGYRGPEGPQGPPGHQGPPG 590 P G+ G KG G G G PG QGP G Sbjct: 678 PPGLMGEKGKLGVPGLPGYPGRQGPKG 704 Score = 272 bits (696), Expect = 1e-72 Identities = 157/358 (43%), Positives = 186/358 (51%), Gaps = 25/358 (6%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RG G RG G G +G G G G G+ G PG GP G+ G KG G G+ G G Sbjct: 739 RGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGH 798 Query: 316 KGYKGE---KGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372 G +GE +GK G G GV G G G G G G G GPPG +G PG G +G Sbjct: 799 PGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 858 Query: 373 KGEPGADGEAGRPGSSGP---SGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGG--- 426 KG+PG G G+ G +G G+ G PG G PG KG G G PGP G+PGERG Sbjct: 859 KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 918 Query: 427 ------PGERGPRGTPGTRGPRGDPGEAGPQGDQGR---EGPVGVPGDPGEAGPIGPKGY 477 PG GP+G PG G +G PGE GP G GR +GPVG+PG G G G G Sbjct: 919 GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGD 978 Query: 478 RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGIN 537 +G+ G PG +G +G G GPPG PG +G G+ G A G +G PG G G+ GA G Sbjct: 979 KGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAA--GADGEPGARGPQGHFGAKGDE 1036 Query: 538 GTKGYPGLKGDEGEAGDPG-----DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 GT+G+ G G G G PG + D+ P G G G RGP GP G G QGPPG Sbjct: 1037 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG 1094 Score = 268 bits (684), Expect = 3e-71 Identities = 171/415 (41%), Positives = 200/415 (48%), Gaps = 74/415 (17%) Query: 251 ECQPARGPPGLRGD----------------PGFEGERGKPGLPGEKGEAGDPGRPGDLGP 294 + Q A GP GL+G+ PG EG G G PG +G G G PG+ GP Sbjct: 264 QSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGP 323 Query: 295 VGYQGMKGEKGSRGEKGS--------------RGPKGYKGE--------------KGKRG 326 G G+ G G+ G G+ +GP E +G G Sbjct: 324 PGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPG 383 Query: 327 IDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPG 386 G G G +G PG PG KG G G QGP GP+G G G G +G GADG G PG Sbjct: 384 PMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPG 443 Query: 387 SSGPSGDEGQPGEPGPPGEKGEAGD---EGNPGPDGAPGERGGPGERGPRGTPGTRGPR- 442 G GD G G PG PGEKG GD +G PGP G GERG GE GPRG PG GPR Sbjct: 444 DPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRG 503 Query: 443 -----GDPGEAGPQGDQGREGPVGVPGD---PGEAGPIGPKGYRGDEGPPGSEGARGAPG 494 G PG GP G +G +GP G G GE GP G +G G +G PG +GA G G Sbjct: 504 LLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHG 563 Query: 495 PAGPPGDPGLMGERGEDGPAGN-GTEGFPGFP------------GYPGNRGAPGINGTKG 541 GP G PGL G G DGP G+ G EG PG GYPG RG G++G +G Sbjct: 564 EKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRG 623 Query: 542 YPGLKGDEGEAGDPGDDNN-----DIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G KG++GE G PG + D GV G++G GPEGP+G G G PGP Sbjct: 624 LKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP 678 Score = 243 bits (621), Expect = 5e-64 Identities = 130/276 (47%), Positives = 155/276 (56%), Gaps = 9/276 (3%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 +GP G RG+ G G+ G+PG PG KG GD G G+ GPVG+ G G G G +G G Sbjct: 1123 KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGA 1182 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKG---SPGFDGIQGPPGPKGDPGAFGLKGE 372 KG +GE G+ G G G GE G PG G +G SPG +G QG G KGDPGA G G+ Sbjct: 1183 KGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGK 1242 Query: 373 KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGP 432 G G G AG+PG G G G G+ G PG G+AG G GP G PG RG G +G Sbjct: 1243 TGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1302 Query: 433 RGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGD------PGEAGPIGPKGYRGDEGPPGS 486 +G PG G G PGE G +GD+G GP G PG PG +GPIGP G G GP G Sbjct: 1303 KGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGP 1362 Query: 487 EGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFP 522 +GA+GA GP GP G+ G+ G G GP G + P Sbjct: 1363 KGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1398 Score = 199 bits (507), Expect = 9e-51 Identities = 137/370 (37%), Positives = 165/370 (44%), Gaps = 93/370 (25%) Query: 309 EKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK------- 361 ++ SR + E + G G+KGE G P + PG ++GPPGP+ Sbjct: 250 QQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVL----EPGML-VEGPPGPEGPAGLIG 304 Query: 362 -----------GDPGAFGLKGEKGEPGADGEAGRPGSS---------------------- 388 GDPG G G G PG+DG G PG+S Sbjct: 305 PPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQE 364 Query: 389 ------------------GPSGDEGQP---GEPGPPGEKGEAGDEGNPGPDGAPGERGGP 427 GP G G+P G+PG PG KGE+GD G GP G G G P Sbjct: 365 AQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPP 424 Query: 428 GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGE---------AGPIGPKGYR 478 G+ G RG G G RG PG+ G +GD+G +G G+PG+ G GP G G R Sbjct: 425 GKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGER 484 Query: 479 GDEGP------PGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-------NGTEGFPGFP 525 GD+G PG G RG GP GPPG PG G RG DGP G G G PG Sbjct: 485 GDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQ 544 Query: 526 GYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAP-----RGVKGAKGYRGPEGPQ 580 G PG +G PG G G G KG +G+ G PG +D P G G KG +GP GPQ Sbjct: 545 GTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQ 604 Query: 581 GPPGHQGPPG 590 GP G+ GP G Sbjct: 605 GPLGYPGPRG 614 Score = 199 bits (505), Expect = 1e-50 Identities = 119/281 (42%), Positives = 140/281 (49%), Gaps = 20/281 (7%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGD---PGRPGDLGPVGYQGMKGEKGSRGEKGSR 313 GP G GDPG GE G G G KG+ G+ PG+PG GP G G G G RG GS Sbjct: 1160 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1219 Query: 314 GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373 G +G +G KG +G G G G+ G G G G PG DG++G PG G G G G+ Sbjct: 1220 GSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQA 1279 Query: 374 GEPGADGEAGRPGSSGPSGDEGQPGEP------GPPGEKGEAGDEGNPGPDGAPGERGGP 427 G PG G G PG G +G +G+ G P GPPGE+GE GD G PGP G+PG++G Sbjct: 1280 GPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEM 1339 Query: 428 GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487 G G G G GP G PG AGP+G +G GP GP G KG +G G PG Sbjct: 1340 GIPGASGPIGPGGPPGLPGPAGPKGAKGATGP---------GGPKGEKGVQGPPGHPGPP 1390 Query: 488 GARGAPGPAGPPGDP--GLMGERGEDGPAGNGTEGFPGFPG 526 G P P P + G R T G PG PG Sbjct: 1391 GEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1431 Score = 186 bits (472), Expect = 1e-46 Identities = 114/269 (42%), Positives = 132/269 (49%), Gaps = 27/269 (10%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS--- 312 RG G +GD G +GE G+PG PG GE G PG G GP G G +G +G +G KG Sbjct: 1177 RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGA 1236 Query: 313 ------RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366 GP G G GK G DG+ G+ G +G G PG G G GP GP G PG Sbjct: 1237 IGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAG---PPGPVGPPGLPGL 1293 Query: 367 ---FGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGE 423 G KGEKG PG G G PG G GD G PG G PG+KGE G G GP G G Sbjct: 1294 RGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP 1353 Query: 424 RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGP-----KGYR 478 G PG GP+G G GP GP+G++G +GP G PG PGE P K R Sbjct: 1354 PGLPGPAGPKGAKGATGP------GGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRR 1407 Query: 479 GDEGPPGSEGARGAPGPAGPPGDPGLMGE 507 +G + P G PG PG + E Sbjct: 1408 SVDGSRLMQEDEAIP-TGGAPGSPGGLEE 1435 Score = 31.2 bits (69), Expect = 5.2 Identities = 13/25 (52%), Positives = 16/25 (64%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGE 279 A GP G +G+ G +G G PG PGE Sbjct: 1368 ATGPGGPKGEKGVQGPPGHPGPPGE 1392 >gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo sapiens] Length = 1736 Score = 305 bits (781), Expect = 1e-82 Identities = 182/428 (42%), Positives = 209/428 (48%), Gaps = 98/428 (22%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GPPG+ G+ G +GE G PG G KG G+ G PG GP+G G G G+ GE G+RGP+ Sbjct: 1075 GPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQ 1134 Query: 317 GYKGEKGK---------------RGIDGVDGVKGE------MGYPGLPGCKGSPGFDGIQ 355 G+ G KG +G+ G G KGE MG PG PG +G G +G Sbjct: 1135 GHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGAD 1194 Query: 356 GPPGPKGDPGAFGLKGEKGEPGADGE---AGRPGSSGP------SGDEGQPGEPGPPGEK 406 GP GP G G G GEKGEPG G G PG GP G+ GQPGEPGPPG K Sbjct: 1195 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK 1254 Query: 407 GEAGDE---GNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEA------------GPQ 451 G GD+ GNPGP G PG+ G PGE GPRG G +G RG+ GE GP Sbjct: 1255 GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPP 1314 Query: 452 GDQGREGPVGVPGD------------------PGEAGPIGPKGYRGDEGP---------- 483 G G+ GP G PG PG+ GP+GP G G GP Sbjct: 1315 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1374 Query: 484 -----PGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN----------GTEGFPGFPGYP 528 PG+ G G PGP GPPG PGL G+ G G G+ G +G G G P Sbjct: 1375 GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1434 Query: 529 GNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGP------QGP 582 G +G+PG G G PG G G G PG P G KGAKG GP GP QGP Sbjct: 1435 GPQGSPGQKGEMGIPGASGPIGPGGPPGLP----GPAGPKGAKGATGPGGPKGEKGVQGP 1490 Query: 583 PGHQGPPG 590 PGH GPPG Sbjct: 1491 PGHPGPPG 1498 Score = 297 bits (760), Expect = 4e-80 Identities = 164/341 (48%), Positives = 189/341 (55%), Gaps = 20/341 (5%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G PG RG G +G RG G GEKGE G PG GD+G G +G G GSRGE G GPK Sbjct: 715 GYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPK 774 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376 G G G G G+ G KG++G PGLPG + G QGP G G PG G GEKG Sbjct: 775 GRTGPTGDPGPPGLMGEKGKLGVPGLPG------YPGRQGPKGSLGFPGFPGASGEKGAR 828 Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436 G G++G G GP+G GQ G G G+ G G G GP G PGERG PG +GP G P Sbjct: 829 GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 888 Query: 437 GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPA 496 G +GP G PG+ G G G+ G VG G G GP G G +G G G G RG PGP Sbjct: 889 GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 948 Query: 497 GPPGDPGLMGERGEDG-------PAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDE 549 GPPG+ GL G G++G P G +G G G+PG RG P GT G PGLKG+E Sbjct: 949 GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLP---GTAGGPGLKGNE 1005 Query: 550 GEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G +G PG + G +GA G GP GP G PG QGPPG Sbjct: 1006 GPSGPPGPAGSP----GERGAAGSGGPIGPPGRPGPQGPPG 1042 Score = 292 bits (748), Expect = 1e-78 Identities = 166/370 (44%), Positives = 199/370 (53%), Gaps = 38/370 (10%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312 Q RGP GL G PG G RG+ G G +G GDPG GD G G G+ GEKG RG+ G+ Sbjct: 519 QGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGA 578 Query: 313 RGPKGYKGEKGKRGID------------GVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP 360 +G G GE G+RG D G G+ G G PG+PG G G DG QGP G Sbjct: 579 QGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGS 638 Query: 361 KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA 420 G G G G++G PG G G G+ GP G++G G+PG PG G G G+PG +G Sbjct: 639 LGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGP 698 Query: 421 PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480 PG +G G GP+G G GPRG G G +G +G +G G G PG G IG KG RG+ Sbjct: 699 PGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGE 758 Query: 481 EGPPGS------EGARGAPGPAGPPGDPGLMGERGEDGPAG----------NGTEGFPGF 524 G PGS EG +G GP G PG PGLMGE+G+ G G G+ GFPGF Sbjct: 759 VGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGF 818 Query: 525 PGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGV---KGAKGYRGPEGPQG 581 PG G +GA G++G G G +G G G G PRG GAKG G +GP G Sbjct: 819 PGASGEKGARGLSGKSGPRGERGPTGPRGQRG-------PRGATGKSGAKGTSGGDGPHG 871 Query: 582 PPGHQGPPGP 591 PPG +G PGP Sbjct: 872 PPGERGLPGP 881 Score = 291 bits (745), Expect = 2e-78 Identities = 173/408 (42%), Positives = 205/408 (50%), Gaps = 72/408 (17%) Query: 257 GPPGLRGDPGFEGERGKPGLPGE---KGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG-- 311 GPPGL G+ G G G PG PG KG G PG PG G G +G+ G+ G RGE+G Sbjct: 784 GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 843 Query: 312 ----SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAF 367 RGP+G G+ G +G G DG G G GLPG +G GF G +GPPGP G G Sbjct: 844 GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLP 903 Query: 368 GLKGEKGEPGADGEAGRPG------------SSGPSGDEGQPGEPGPPGEKG------EA 409 G G++GE G G+ G PG +GP G+ G PG PGPPGE+G + Sbjct: 904 GHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKE 963 Query: 410 GDEGNPGPDGAPGE------RGGPGERG---------------------PRGTPGTRGPR 442 G +G+PGP GAPG+ RG PGERG P G+PG RG Sbjct: 964 GTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAA 1023 Query: 443 GDPGEAGPQGDQGREGPVGVPGD---PGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPP 499 G G GP G G +GP G G+ PGE GPIGP G G +GP G G G PG AG Sbjct: 1024 GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGED 1083 Query: 500 GDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDD 558 GD G +G+ G+ G GN G G PG PG G G PG G G PG +G +G G GD+ Sbjct: 1084 GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1143 Query: 559 NND--------------IAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592 P G KG G GP GP GPPG +GP GP+ Sbjct: 1144 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPN 1191 Score = 281 bits (719), Expect = 2e-75 Identities = 158/346 (45%), Positives = 182/346 (52%), Gaps = 20/346 (5%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQG------MKGEKGSRGEK 310 GPPG G G G G+ G+PGEKG G GR G GPVG G + GE G +GE Sbjct: 1030 GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 1089 Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370 G G KG KG KG+ G G G G +G PG G G PG G QG G KGD G G Sbjct: 1090 GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFN 1149 Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPG---ERGGP 427 G G G G G G G +GD G G PGPPG +G AG G GP G PG G P Sbjct: 1150 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPP 1209 Query: 428 GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487 GE+G G G+ G +G+PG GP+G++G +G G PG+P GP GPKG GD+GP G+ Sbjct: 1210 GEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEP---GPPGPKGPTGDDGPKGNP 1266 Query: 488 GARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGTKGYPGLK 546 G G PG GPPG+ G G+ G G G +G G PG PG G G PG G +G G Sbjct: 1267 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1326 Query: 547 GDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592 G EG G G +G GA G G GP GP G G PGPD Sbjct: 1327 GSEGRQGGKG-------AKGDPGAIGAPGKTGPVGPAGPAGKPGPD 1365 Score = 279 bits (714), Expect = 8e-75 Identities = 164/350 (46%), Positives = 183/350 (52%), Gaps = 26/350 (7%) Query: 257 GPPGLRGDPGFEGERGKPGL---PGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSR 313 GPPG RG PG +G G PG PG G+ G PG PG G VG+QG G G G G + Sbjct: 871 GPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ 930 Query: 314 GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373 G G G G+RG G G GE G LPG G G G GPPG G G GL+G Sbjct: 931 GAAGETGPMGERGHPGPPGPPGEQG---LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFP 987 Query: 374 GEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD------EGNPGPDGAP---GER 424 GE G G AG PG G G G PG G PGE+G AG G PGP G P GE+ Sbjct: 988 GERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEK 1047 Query: 425 GGPGER---GPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE 481 G PGE+ GP G G +GP G PG AGP G G +G G GDPG+ G G KG G Sbjct: 1048 GVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPP 1107 Query: 482 GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTK 540 GPPG G G PG AG G+PG G +G G G+ GT GF G PG G +G PG +G K Sbjct: 1108 GPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEK 1167 Query: 541 GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G G G G G PG PRG G G GP+GP G G+ GPPG Sbjct: 1168 GETGDVGPMGPPGPPG-------PRGPAGPNGADGPQGPPGGVGNLGPPG 1210 Score = 279 bits (713), Expect = 1e-74 Identities = 161/377 (42%), Positives = 189/377 (50%), Gaps = 51/377 (13%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGE------ 309 RG PG G PG +G G G G KG+ G PG PG GP G +G GE+G G Sbjct: 942 RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGL 1001 Query: 310 KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGL 369 KG+ GP G G G G G G G +G PG PG +G PG G +G PG KG G G Sbjct: 1002 KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGR 1061 Query: 370 KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGE 429 G +G G G AG PG +G GD+G+ G+PG G KG G+ G PGP G G G PG Sbjct: 1062 DGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1121 Query: 430 RGPRGTPGTRGPRGD------------------------PGEAGPQGDQGREGPVGVPGD 465 G G PG RGP+G PG +G +G+ G GP+G PG Sbjct: 1122 AGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP 1181 Query: 466 PGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGD---PGLMGE---------RGEDGP 513 PG GP GP G G +GPPG G G PG G PG+ PG+ GE RGE G Sbjct: 1182 PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGE 1241 Query: 514 AGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573 +G PG PG PG +G G +G KG PG G G+ G PG+ PRG GAKG Sbjct: 1242 SGQ-----PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEG----GPRGQDGAKGD 1292 Query: 574 RGPEGPQGPPGHQGPPG 590 RG +G G PG GP G Sbjct: 1293 RGEDGEPGQPGSPGPTG 1309 Score = 277 bits (709), Expect = 3e-74 Identities = 165/378 (43%), Positives = 194/378 (51%), Gaps = 45/378 (11%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP---VGYQGMKGEKGSRGE 309 Q G PG +G PG G+ G PG PG++GE G G+ G GP VG QG GE G GE Sbjct: 882 QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 941 Query: 310 KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPG---FDGIQGPPGPKGDPGA 366 +G GP G GE+G G G +G KG+ G PG PG G G F G +G PG G PG Sbjct: 942 RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGL 1001 Query: 367 FGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGP------------PGEKGEAGDEGN 414 G +G G PG G G G++G G G PG PGP PGEKG G G Sbjct: 1002 KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGR 1061 Query: 415 ---------PGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVP-- 463 PGP G PG G G++G G PG +G +G+ GE GP G G GPVG P Sbjct: 1062 DGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1121 Query: 464 ----GDPGEAGPIGPKGYRGDE------GPPGSEGARGAPGPAGPPGDPGLMGERGEDGP 513 G+PG GP G G +GDE GPPG G +G PGP+G G+ G +G G GP Sbjct: 1122 AGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP 1181 Query: 514 AGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573 G G G G G +G PG G G PG KG+ GE+G PG GVKG +G Sbjct: 1182 P--GPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEP----GVKGPRGE 1235 Query: 574 RGPEGPQGPPGHQGPPGP 591 RG +G G PG GPPGP Sbjct: 1236 RGEKGESGQPGEPGPPGP 1253 Score = 277 bits (708), Expect = 4e-74 Identities = 163/387 (42%), Positives = 190/387 (49%), Gaps = 55/387 (14%) Query: 256 RGPPGLRGDPGFEGERGKPG-------------------------------------LPG 278 RGPPG G PG +G G PG L G Sbjct: 428 RGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRG 487 Query: 279 EKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMG 338 G G GRPG LG G G+KGE G G +G RGP+G G GK G G G G G Sbjct: 488 PPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARG 547 Query: 339 YPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGE---------AGRPGSSG 389 PG PG KG GFDG+ G PG KG G G +G G PG DGE G PG SG Sbjct: 548 MPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESG 607 Query: 390 PSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAG 449 P G G G PG PG G G +G GP G+ G +G PG G +GTPGT+G G G G Sbjct: 608 PRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIG 667 Query: 450 PQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERG 509 P G++G +G G+PG PG GP G+ G EGPPG++G +G GP GP G PG G +G Sbjct: 668 PHGEKGPQGKPGLPGMPGSD---GPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKG 724 Query: 510 EDGPAG----NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPG--DDNNDIA 563 DG G G +G GFPG+ G+ G G G G PG +G++G G G D Sbjct: 725 VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG 784 Query: 564 PRGVKGAKGYRGPEGPQGPPGHQGPPG 590 P G+ G KG G G G PG QGP G Sbjct: 785 PPGLMGEKGKLGVPGLPGYPGRQGPKG 811 Score = 272 bits (696), Expect = 1e-72 Identities = 157/358 (43%), Positives = 186/358 (51%), Gaps = 25/358 (6%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RG G RG G G +G G G G G+ G PG GP G+ G KG G G+ G G Sbjct: 846 RGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGH 905 Query: 316 KGYKGE---KGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372 G +GE +GK G G GV G G G G G G G GPPG +G PG G +G Sbjct: 906 PGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 965 Query: 373 KGEPGADGEAGRPGSSGP---SGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGG--- 426 KG+PG G G+ G +G G+ G PG G PG KG G G PGP G+PGERG Sbjct: 966 KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 1025 Query: 427 ------PGERGPRGTPGTRGPRGDPGEAGPQGDQGR---EGPVGVPGDPGEAGPIGPKGY 477 PG GP+G PG G +G PGE GP G GR +GPVG+PG G G G G Sbjct: 1026 GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGD 1085 Query: 478 RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGIN 537 +G+ G PG +G +G G GPPG PG +G G+ G A G +G PG G G+ GA G Sbjct: 1086 KGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAA--GADGEPGARGPQGHFGAKGDE 1143 Query: 538 GTKGYPGLKGDEGEAGDPG-----DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 GT+G+ G G G G PG + D+ P G G G RGP GP G G QGPPG Sbjct: 1144 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG 1201 Score = 267 bits (683), Expect = 3e-71 Identities = 169/399 (42%), Positives = 197/399 (49%), Gaps = 60/399 (15%) Query: 253 QPARGPPGL--RGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310 +PA PG+ G PG EG G G PG +G G G PG+ GP G G+ G G+ G Sbjct: 387 EPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPP 446 Query: 311 GS--------------RGPKGYKGE--------------KGKRGIDGVDGVKGEMGYPGL 342 G+ +GP E +G G G G G +G PG Sbjct: 447 GTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGS 506 Query: 343 PGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGP 402 PG KG G G QGP GP+G G G G +G GADG G PG G GD G G PG Sbjct: 507 PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGL 566 Query: 403 PGEKGEAGD---EGNPGPDGAPGERGGPGERGPRGTPGTRGPR------GDPGEAGPQGD 453 PGEKG GD +G PGP G GERG GE GPRG PG GPR G PG GP G Sbjct: 567 PGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV 626 Query: 454 QGREGPVGVPGD---PGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGE 510 +G +GP G G GE GP G +G G +G PG +GA G G GP G PGL G G Sbjct: 627 RGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGS 686 Query: 511 DGPAGN-GTEGFPGFP------------GYPGNRGAPGINGTKGYPGLKGDEGEAGDPGD 557 DGP G+ G EG PG GYPG RG G++G +G G KG++GE G PG Sbjct: 687 DGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF 746 Query: 558 DNN-----DIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 + D GV G++G GPEGP+G G G PGP Sbjct: 747 KGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP 785 Score = 243 bits (621), Expect = 5e-64 Identities = 130/276 (47%), Positives = 155/276 (56%), Gaps = 9/276 (3%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 +GP G RG+ G G+ G+PG PG KG GD G G+ GPVG+ G G G G +G G Sbjct: 1230 KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGA 1289 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKG---SPGFDGIQGPPGPKGDPGAFGLKGE 372 KG +GE G+ G G G GE G PG G +G SPG +G QG G KGDPGA G G+ Sbjct: 1290 KGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGK 1349 Query: 373 KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGP 432 G G G AG+PG G G G G+ G PG G+AG G GP G PG RG G +G Sbjct: 1350 TGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1409 Query: 433 RGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGD------PGEAGPIGPKGYRGDEGPPGS 486 +G PG G G PGE G +GD+G GP G PG PG +GPIGP G G GP G Sbjct: 1410 KGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGP 1469 Query: 487 EGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFP 522 +GA+GA GP GP G+ G+ G G GP G + P Sbjct: 1470 KGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1505 Score = 199 bits (507), Expect = 9e-51 Identities = 146/399 (36%), Positives = 173/399 (43%), Gaps = 98/399 (24%) Query: 282 EAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGI--DGVDGVKGEMGY 339 E G+ G GP Y G+ E+ GP E G G G+KGE G Sbjct: 331 EYGEGGTDPPEGPYDYTYGYGD--DYREETELGP-ALSAETAHSGAAAHGPRGLKGEKGE 387 Query: 340 PGLPGCKGSPGFDGIQGPPGPK------------------GDPGAFGLKGEKGEPGADGE 381 P + PG ++GPPGP+ GDPG G G G PG+DG Sbjct: 388 PAVL----EPGML-VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGA 442 Query: 382 AGRPGSS----------------------------------------GPSGDEGQP---G 398 G PG+S GP G G+P G Sbjct: 443 PGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLG 502 Query: 399 EPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREG 458 +PG PG KGE+GD G GP G G G PG+ G RG G G RG PG+ G +GD+G +G Sbjct: 503 QPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDG 562 Query: 459 PVGVPGDPGE---------AGPIGPKGYRGDEGP------PGSEGARGAPGPAGPPGDPG 503 G+PG+ G GP G G RGD+G PG G RG GP GPPG PG Sbjct: 563 LPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPG 622 Query: 504 LMGERGEDGPAG-------NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPG 556 G RG DGP G G G PG G PG +G PG G G G KG +G+ G PG Sbjct: 623 PPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPG 682 Query: 557 DDNNDIAP-----RGVKGAKGYRGPEGPQGPPGHQGPPG 590 +D P G G KG +GP GPQGP G+ GP G Sbjct: 683 MPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRG 721 Score = 199 bits (505), Expect = 1e-50 Identities = 119/281 (42%), Positives = 140/281 (49%), Gaps = 20/281 (7%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGD---PGRPGDLGPVGYQGMKGEKGSRGEKGSR 313 GP G GDPG GE G G G KG+ G+ PG+PG GP G G G G RG GS Sbjct: 1267 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1326 Query: 314 GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373 G +G +G KG +G G G G+ G G G G PG DG++G PG G G G G+ Sbjct: 1327 GSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQA 1386 Query: 374 GEPGADGEAGRPGSSGPSGDEGQPGEP------GPPGEKGEAGDEGNPGPDGAPGERGGP 427 G PG G G PG G +G +G+ G P GPPGE+GE GD G PGP G+PG++G Sbjct: 1387 GPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEM 1446 Query: 428 GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487 G G G G GP G PG AGP+G +G GP GP G KG +G G PG Sbjct: 1447 GIPGASGPIGPGGPPGLPGPAGPKGAKGATGP---------GGPKGEKGVQGPPGHPGPP 1497 Query: 488 GARGAPGPAGPPGDP--GLMGERGEDGPAGNGTEGFPGFPG 526 G P P P + G R T G PG PG Sbjct: 1498 GEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1538 Score = 186 bits (472), Expect = 1e-46 Identities = 114/269 (42%), Positives = 132/269 (49%), Gaps = 27/269 (10%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS--- 312 RG G +GD G +GE G+PG PG GE G PG G GP G G +G +G +G KG Sbjct: 1284 RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGA 1343 Query: 313 ------RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366 GP G G GK G DG+ G+ G +G G PG G G GP GP G PG Sbjct: 1344 IGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAG---PPGPVGPPGLPGL 1400 Query: 367 ---FGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGE 423 G KGEKG PG G G PG G GD G PG G PG+KGE G G GP G G Sbjct: 1401 RGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP 1460 Query: 424 RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGP-----KGYR 478 G PG GP+G G GP GP+G++G +GP G PG PGE P K R Sbjct: 1461 PGLPGPAGPKGAKGATGP------GGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRR 1514 Query: 479 GDEGPPGSEGARGAPGPAGPPGDPGLMGE 507 +G + P G PG PG + E Sbjct: 1515 SVDGSRLMQEDEAIP-TGGAPGSPGGLEE 1542 Score = 31.2 bits (69), Expect = 5.2 Identities = 13/25 (52%), Positives = 16/25 (64%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGE 279 A GP G +G+ G +G G PG PGE Sbjct: 1475 ATGPGGPKGEKGVQGPPGHPGPPGE 1499 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 303 bits (775), Expect = 7e-82 Identities = 166/357 (46%), Positives = 196/357 (54%), Gaps = 29/357 (8%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G PG+ G G G RG+ G+ G+KG+ G G PG GP+G QG+ G G +GE G GP Sbjct: 1171 GAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPM 1230 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGC------KGSPGFDGIQGPPGPKGDPGAFGLK 370 G G G RG G +G G G PG G KG PG G GPPG G G G + Sbjct: 1231 GPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGER 1290 Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQ---------PGEPGPPGEKGEAGDEG---NPGPD 418 GEKGE G G AG PG+ GP GD+G PG+PGPPGE G AG +G + G D Sbjct: 1291 GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGED 1350 Query: 419 GAPGERGGPG---ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475 G PG+ G PG E GP G PG RGP G G G QG++G +G G G PG+ GP+GP+ Sbjct: 1351 GDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQ 1410 Query: 476 GYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAP 534 G G PG EG RG PGP G G PG G+ G GP G G G G PG G +G P Sbjct: 1411 G---PAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHP 1467 Query: 535 GINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G+ G G PG +G++G+ G PG + G KG G GP GP GPPG G PGP Sbjct: 1468 GLIGLIGPPGEQGEKGDRGLPGTQGSP----GAKGDGGIPGPAGPLGPPGPPGLPGP 1520 Score = 296 bits (758), Expect = 7e-80 Identities = 170/376 (45%), Positives = 199/376 (52%), Gaps = 47/376 (12%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 +G PGL G PG +G G PG G+ GE G G PG GP+GY G +G KG+ G +G +G Sbjct: 729 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 788 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375 KG KGE G G G G+KG+ G G G +G G +G +G GP GDPG G GEKG+ Sbjct: 789 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 848 Query: 376 PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP---------GPDGAPGERGG 426 G G G PG GP G G PG PG GEKG G G P GP G+ G RG Sbjct: 849 LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 908 Query: 427 PGERGPRGTPGTRGPRGDPGEAGPQGDQGR---EGPVGVPGDP----------------- 466 G+ GP+GT G GP G PGE GPQG QG GP G PG P Sbjct: 909 TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGF 968 Query: 467 -GEAGPIGPKGYRGDEGPPGSE---GARGAPGPAGPPGDPGLMGERGEDGPAG------- 515 G+ GP GP G G +GP G G RG PGP GPPG+ GL G G++G G Sbjct: 969 QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGI 1028 Query: 516 NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRG 575 +G +G G G+PG RG P G +G PGLKG EG G PG + G +G+ G G Sbjct: 1029 SGKDGPAGLRGFPGERGLP---GAQGAPGLKGGEGPQGPPG----PVGSPGERGSAGTAG 1081 Query: 576 PEGPQGPPGHQGPPGP 591 P G G PG QGPPGP Sbjct: 1082 PIGLPGRPGPQGPPGP 1097 Score = 295 bits (754), Expect = 2e-79 Identities = 163/357 (45%), Positives = 197/357 (55%), Gaps = 21/357 (5%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G PG RG+ GF+G+ G PG G G G G G +G G+ G G G +G G+ G + Sbjct: 958 GHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKE 1017 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPG---LPGCKGSPGF---DGIQGPPGPKGDPGAFGLK 370 G KG+ G +GI G DG G G+PG LPG +G+PG +G QGPPGP G PG G Sbjct: 1018 GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA 1077 Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGN---PGPDGAPGERGGP 427 G G G G G G GP+G++G PGE GP G G G +G PGP G G G Sbjct: 1078 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGED 1137 Query: 428 GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487 G++G G PG +G +GD GE GP G G +GPVG PG G G GP+G +G G G E Sbjct: 1138 GDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDE 1197 Query: 488 GARGAPGPAGP------PGDPGLMGERGEDGPAG----NGTEGFPGFPGYPGNRGAPGIN 537 GARG PGP GP PG PG GE G+ GP G G G G G G +G PG Sbjct: 1198 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV 1257 Query: 538 GTKGYPGLKGDEGEAGDPG--DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592 G+ G G KG+ GEAG+PG + P+G +G KG GP G GPPG +GPPG D Sbjct: 1258 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDD 1314 Score = 294 bits (752), Expect = 3e-79 Identities = 157/351 (44%), Positives = 190/351 (54%), Gaps = 17/351 (4%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G PG RG PG +G RG PG PG KG+ G G PG G G++G +G +G G G G + Sbjct: 586 GKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMR 645 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD---------PGAF 367 G GE G RG+ G G +G +G G PG G PG G+ GPPGPKG+ PG Sbjct: 646 GEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQ 705 Query: 368 GLKGEKGEPGADGEAGRPGSSGPSGDEGQ---PGEPGP---PGEKGEAGDEGNPGPDGAP 421 G G +G PG G G PG GP G G PG GP PG++G++G++G GP G Sbjct: 706 GNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQ 765 Query: 422 GERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE 481 G G PG RG +G G RG +G GE G G G +G +G+ GD GE G IGP+G G E Sbjct: 766 GPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPE 825 Query: 482 GPPGSEGARGAPGPAGPPGDPGLMGERGEDG-PAGNGTEGFPGFPGYPGNRGAPGINGTK 540 GP G G G PGP+G G+ G +G G G P G +G GFPG+PG G G G Sbjct: 826 GPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA 885 Query: 541 GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G PG +G G G P P G G KG G +GP GPPG +GP GP Sbjct: 886 GKPGPRGQRGPTG-PRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGP 935 Score = 291 bits (744), Expect = 3e-78 Identities = 176/376 (46%), Positives = 204/376 (54%), Gaps = 44/376 (11%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGR---PGDLGPVGYQGMKGEKGSRGEKG 311 A+G PGL+G G +G G G PGE+G AG G PG GP G G GEKG+ GEKG Sbjct: 1049 AQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG 1108 Query: 312 SRGPKGYKGEKGKRGI---------DGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKG 362 +GP G G +G G+ G DG KGE+G PG G KG G +G GPPG +G Sbjct: 1109 PQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQG 1168 Query: 363 DPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE---------PGPPGEKGEAGDEG 413 GA G+ G GEPG G+ G G G G G PG PGPPGEKGE GD G Sbjct: 1169 PVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVG 1228 Query: 414 NPGPDGAPGERG--GP-GERGPRGTPGT------RGPRGDPGEA---GPQGDQGREGPVG 461 GP G PG RG GP G GP+G PG+ G +G+PGEA GP G+ G GP G Sbjct: 1229 PMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKG 1288 Query: 462 VPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGE---RGEDGPAGN-G 517 G+ GEAGP G G G +GPPG +G +G PGP G PGDPG GE G+DG G+ G Sbjct: 1289 ERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKG 1348 Query: 518 TEGFPGFPGYP---GNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYR 574 +G PG PG P G G PG G +G PG G EG G+ G G +G G Sbjct: 1349 EDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE----AGAEGPPGKT 1404 Query: 575 GPEGPQGPPGHQGPPG 590 GP GPQGP G GP G Sbjct: 1405 GPVGPQGPAGKPGPEG 1420 Score = 289 bits (739), Expect = 1e-77 Identities = 162/348 (46%), Positives = 187/348 (53%), Gaps = 20/348 (5%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLG---PVGYQGMKGEKGSRGEKGSR 313 G PG +G PG GE+G PG G +G AG G G +G P G G GE G +GE G Sbjct: 1087 GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEP 1146 Query: 314 GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373 G KG KG+KG+ G G G++G +G PG+ G G PG G QG G KGD GA G G Sbjct: 1147 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPP 1206 Query: 374 GEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPR 433 G G G G PG G +GD G G PGPPG +G G G GP G PG G G G + Sbjct: 1207 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1266 Query: 434 GTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAP 493 G PG G G PGEAG G +G G G G PG AGP G KG GD+GP G+ G G P Sbjct: 1267 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFP 1326 Query: 494 GPAGPPGDP------GLMGERGEDGPAGN----GTEGFPGFPGYPGNRGAPGINGTKGYP 543 G GPPG+P G+ G++GEDG G G G G PG PG RG PG G +G Sbjct: 1327 GDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ 1386 Query: 544 GLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G KG +GEAG G P G G G +GP G GP G +G PGP Sbjct: 1387 GEKGAKGEAGAEG-------PPGKTGPVGPQGPAGKPGPEGLRGIPGP 1427 Score = 288 bits (737), Expect = 2e-77 Identities = 166/364 (45%), Positives = 195/364 (53%), Gaps = 31/364 (8%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP------VGYQGMKGEKGSRGE 309 RGP G RG G G GKPG G G G PG PG+ GP VG+ G KG G G+ Sbjct: 894 RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGK 953 Query: 310 KGSRGPKGYKGE---KGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366 G G G +GE +GK G G GV G G G G G G G GPPG +G PGA Sbjct: 954 DGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGA 1013 Query: 367 FGLKGEKGEPGADGEAGRPGSSGPSG---DEGQPGEPGPPGEKGEAGDEGNPGPDGAPGE 423 G +G KG+PG G +G+ G +G G + G PG G PG KG G +G PGP G+PGE Sbjct: 1014 AGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGE 1073 Query: 424 RGG---------PGERGPRGTPGTRGPRGDPGEAGPQGDQGR---EGPVGVPGDPGEAGP 471 RG PG GP+G PG G +G PGE GPQG GR +GPVG+PG G AG Sbjct: 1074 RGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1133 Query: 472 IGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNR 531 G G +G+ G PG +G++G G GPPG PGL G G G AG +G PG G G Sbjct: 1134 PGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG--DGEPGPRGQQGMF 1191 Query: 532 GAPGINGTKGYPGLKGDEGEAGDPG-----DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQ 586 G G G +G+PG G G G PG +N D+ P G G G RGP+GP G G Q Sbjct: 1192 GQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1251 Query: 587 GPPG 590 GPPG Sbjct: 1252 GPPG 1255 Score = 286 bits (732), Expect = 7e-77 Identities = 170/393 (43%), Positives = 194/393 (49%), Gaps = 63/393 (16%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RGPPG G G G G PG G KGE+GDPG G G G G G+ G RG G+ G Sbjct: 540 RGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGG 599 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375 +G GE G +G G DG+ PGLPG KG G G QGPPGP GD G G GE G Sbjct: 600 RGMPGEPGAKGDRGFDGL------PGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP 653 Query: 376 PGADGEAGRPGSSGPSGDEGQPGEP------GPPGEKGEAGDEGNPGP---DGAPGERGG 426 G GEAG G GP G G PG+P GPPG KG G +G PGP G PG +G Sbjct: 654 RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 713 Query: 427 PGERGPRGTPGTRGPRGDPGEA------GPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480 PG +GP G PG +GP+G PG A GP G G+EG G G G GP GP GY G Sbjct: 714 PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGP 773 Query: 481 EGPPGSEGARGAPGPAGPPGDPGL------------------MGERGEDGPAG------- 515 G G++G RG G G G+ G +G RGEDGP G Sbjct: 774 RGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP 833 Query: 516 ------------NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGE---AGDPG--DD 558 G G PG PGYPG +G G G G+PG G++G AG PG Sbjct: 834 TGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQ 893 Query: 559 NNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 PRG +GA+G G GP+G G GPPGP Sbjct: 894 RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGP 926 Score = 284 bits (727), Expect = 3e-76 Identities = 157/346 (45%), Positives = 187/346 (54%), Gaps = 21/346 (6%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314 A G GL+G G +GE G PG G+ G GD G G +GP G G +G KG G G G Sbjct: 779 ADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 838 Query: 315 PKGYKGEKGKRGIDGVDGV------KGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFG 368 P G GEKGK G+ G+ G KG G+PG PG G G G+ G PGP+G G G Sbjct: 839 PSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTG 898 Query: 369 LKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPG 428 +G +G A G G+PG G SG +G PG PPGE+G G + GP G PG +G PG Sbjct: 899 PRGSRG---ARGPTGKPGPKGTSGGDGPPG---PPGERGPQGPQ---GPVGFPGPKGPPG 949 Query: 429 ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEG 488 G G PG G RG+ G G G G G VG G GE GPIG +G+ G GPPG +G Sbjct: 950 PPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQG 1009 Query: 489 ARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGD 548 GA G G GDPG G G+DGPA G GFPG G PG +GAPG+ G +G G G Sbjct: 1010 LPGAAGKEGAKGDPGPQGISGKDGPA--GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGP 1067 Query: 549 EGEAGDPGDDNNDIAPRGVKGAKGYRGPEGP---QGPPGHQGPPGP 591 G G+ G P G+ G G +GP GP +G PG +GP GP Sbjct: 1068 VGSPGERGSAGT-AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGP 1112 Score = 284 bits (726), Expect = 3e-76 Identities = 157/342 (45%), Positives = 188/342 (54%), Gaps = 13/342 (3%) Query: 257 GPPGLRGDPGFEGERGKPGLPG------EKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310 G PG G G +G+ G PGLPG KG G PG PG G G +G+ G+ G RG++ Sbjct: 835 GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 894 Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370 G GP+G +G +G G G G G G PG PG +G G G G PGPKG PG G Sbjct: 895 GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 954 Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGER 430 G G PG GE G G +GP G G G GP GE G G+ G+PGP G PGE+G PG Sbjct: 955 GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 1014 Query: 431 GPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGAR 490 G G G GP+G G+ GP G +G G G+PG G G G +G +G GP GS G R Sbjct: 1015 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1074 Query: 491 GAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEG 550 G+ G AGP G PG G +G GPAG G PG G +G G +G +G GL G G Sbjct: 1075 GSAGTAGPIGLPGRPGPQGPPGPAGE-----KGAPGEKGPQGPAGRDGVQGPVGLPGPAG 1129 Query: 551 EAGDPGDDNN--DIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 AG PG+D + +I G KG+KG +G GP GPPG QGP G Sbjct: 1130 PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG 1171 Score = 284 bits (726), Expect = 3e-76 Identities = 164/365 (44%), Positives = 189/365 (51%), Gaps = 41/365 (11%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGD------PGRPGDLGPVGYQGMKGEKGSRGEK 310 G G G PG G +G PG PGEKGE GD PG PG GP G G G +G G Sbjct: 1198 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV 1257 Query: 311 GSRGPKGYKGEKGKRG---------IDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361 GS G G KGE G+ G + G G +GE G G PG G PG G G GPK Sbjct: 1258 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK 1317 Query: 362 GDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP---GPD 418 G+PG G G+ G PG G AG+ G G G++G PG+PGPPG GEAG G P GP Sbjct: 1318 GNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPP 1377 Query: 419 GAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYR 478 GA G G GE+G +G G GP G G GPQG G+ GP G+ G PG Sbjct: 1378 GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV--------- 1428 Query: 479 GDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGIN 537 G++G PG+ G G PGP GPPG PGL G+ G G G+ G G G PG G +G G+ Sbjct: 1429 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1488 Query: 538 GTKGYPGLKGD------EGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQ------GPPGH 585 GT+G PG KGD G G PG P+G KG KG GP G + GPPG Sbjct: 1489 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLP-GPQGPKGNKGSTGPAGQKGDSGLPGPPGS 1547 Query: 586 QGPPG 590 GPPG Sbjct: 1548 PGPPG 1552 Score = 282 bits (722), Expect = 1e-75 Identities = 168/378 (44%), Positives = 193/378 (51%), Gaps = 44/378 (11%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G G G PG GE+G PG G++G GDPG G G G G++G G RG G++G Sbjct: 994 GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1053 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376 G KG +G +G G G GE G G G G PG G QGPPGP G+ GA G KG +G Sbjct: 1054 GLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPA 1113 Query: 377 GAD---------GEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPD------GAP 421 G D G AG GS G GD+G+ GEPG G KG+ G+ G PGP GAP Sbjct: 1114 GRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAP 1173 Query: 422 GERGGPGERGPRGTPGTRGPRGD------------------PGEAGPQGDQGREGPVGVP 463 G GG GE GPRG G G +GD PG G +G+ G GP+G P Sbjct: 1174 GIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1233 Query: 464 GDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGD---PGLMGERGEDGPAG----N 516 G PG GP GP G G +GPPGS G+ G G G PG+ PG GE G GP G Sbjct: 1234 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1293 Query: 517 GTEGFPGFPGYPGNRGAPGINGTKGYP---GLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573 G G PG G PG +G PG +G KG P G GD G G+PG D G KG G Sbjct: 1294 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQD-GVGGDKGEDGD 1352 Query: 574 RGPEGPQGPPGHQGPPGP 591 G GP GP G GPPGP Sbjct: 1353 PGQPGPPGPSGEAGPPGP 1370 Score = 281 bits (720), Expect = 2e-75 Identities = 165/374 (44%), Positives = 196/374 (52%), Gaps = 41/374 (10%) Query: 257 GPPGLRGDPG---FEGERGKPGLPGEKGEAGDPGR---PGDLGPVGYQGMKGEKGSRGEK 310 GPPG +G+PG G +G G PGEKG G PG PG GP G+ G +G+ G +G Sbjct: 700 GPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL 759 Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370 G GP+G G G RG+ G DGV+G G G G G PGF G G G +G+ G G + Sbjct: 760 GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 819 Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQ------PGEPGPPGEKGEAGDEGNPGPDGAPGER 424 GE G G G AG G GPSG G+ PG PG PG +G G G PG GA GE+ Sbjct: 820 GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 879 Query: 425 G--------GP-GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475 G GP G+RGP G G+RG RG G+ GP+G G +GP G PG+ G GP GP Sbjct: 880 GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPV 939 Query: 476 GYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-------------NGTEGFP 522 G+ G +GPPG G G PG G G+ G G+ G GP G G G P Sbjct: 940 GFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHP 999 Query: 523 GFPGYPGNRGAPGI---NGTKGYP---GLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGP 576 G PG PG +G PG G KG P G+ G +G AG G P G +GA G +G Sbjct: 1000 GPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLP-GAQGAPGLKGG 1058 Query: 577 EGPQGPPGHQGPPG 590 EGPQGPPG G PG Sbjct: 1059 EGPQGPPGPVGSPG 1072 Score = 278 bits (710), Expect = 2e-74 Identities = 159/350 (45%), Positives = 190/350 (54%), Gaps = 23/350 (6%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G PGL GD G GERG G PG G+ G G G++GP +G+ GE G RG G RG Sbjct: 616 GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP---RGLPGEAGPRGLLGPRGTP 672 Query: 317 GYKGEKGKRGIDGVDGVKGEMG---YPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373 G G+ G G+DG G KG MG PG PG +G+PG G+ GP GP G PG G +G+ Sbjct: 673 GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP 732 Query: 374 GE---PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGER 430 G PGADG G PG G SG++G G PGP G G G G G DG G +G GE+ Sbjct: 733 GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK 792 Query: 431 GPRGTPG------TRGPRGDPGEAGPQGDQGREGP---VGVPGDPGEAGPIGPKGYRGDE 481 G G PG +G RG+ G+ GP+G+ G EGP G GDPG +G G KG G Sbjct: 793 GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP 852 Query: 482 GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTK 540 G PG G +G G G PG PG GE+G G AG G G G G G+RGA G G Sbjct: 853 GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKP 912 Query: 541 GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G G G +G G PG+ P+G +G G+ GP+GP GPPG G PG Sbjct: 913 GPKGTSGGDGPPGPPGER----GPQGPQGPVGFPGPKGPPGPPGKDGLPG 958 Score = 277 bits (709), Expect = 3e-74 Identities = 157/344 (45%), Positives = 182/344 (52%), Gaps = 21/344 (6%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RGP G +G GF G +G PG PG+ G PG PG G G+QG G G G G +GP Sbjct: 930 RGPQGPQGPVGFPGPKGPPGPPGKDGL---PGHPGQRGETGFQGKTGPPGPGGVVGPQGP 986 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375 G G G+RG G G GE G PG G +G+ G G QG G G G G GE+G Sbjct: 987 TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL 1046 Query: 376 PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD---EGNPGPDGAPG---ERGGPGE 429 PGA G G G GP G G G PG G G AG G PGP G PG E+G PGE Sbjct: 1047 PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1106 Query: 430 RGPRGTPG---TRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGS 486 +GP+G G +GP G PG AGP G G +G G G+PG+ G G KG G GPPG Sbjct: 1107 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1166 Query: 487 EGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLK 546 +G GAPG AG G+PG G++G G G+ EG GFPG PG G G+ G G G Sbjct: 1167 QGPVGAPGIAGGDGEPGPRGQQGMFGQKGD--EGARGFPGPPGPIGLQGLPGPPGEKGEN 1224 Query: 547 GDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 GD G G PG P G +G +G G +GPQGPPG G G Sbjct: 1225 GDVGPMGPPG-------PPGPRGPQGPNGADGPQGPPGSVGSVG 1261 Score = 276 bits (705), Expect = 9e-74 Identities = 161/369 (43%), Positives = 187/369 (50%), Gaps = 36/369 (9%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RG PG +G PG +G G G PG G G+ G G GP+G + G G +G G G Sbjct: 1044 RGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIG---LPGRPGPQGPPGPAGE 1100 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGP---PGPKGDPGAFGLKGE 372 KG GEKG +G G DGV+G +G PG G GSPG DG +G PG KG G G G Sbjct: 1101 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP 1160 Query: 373 KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGP 432 G PG G G PG +G G+ G G+ G G+KG+ G G PGP G G +G PG G Sbjct: 1161 PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1220 Query: 433 RGTPGTRGPRGDPGEAGPQGDQ---GREGPVGVP------------GDPGEAGPIGPKGY 477 +G G GP G PG GP+G Q G +GP G P G+PGEAG GP G Sbjct: 1221 KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1280 Query: 478 RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGI 536 G GP G G +G GP G G PG G G+DGP GN G GFPG PG PG G G Sbjct: 1281 AGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQ 1340 Query: 537 NGT---------KGYPGLKGDEGEAGDPGDDNNDIAP-----RGVKGAKGYRGPEGPQGP 582 +G G PG G GEAG PG P G +G KG +G G +GP Sbjct: 1341 DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP 1400 Query: 583 PGHQGPPGP 591 PG GP GP Sbjct: 1401 PGKTGPVGP 1409 Score = 275 bits (704), Expect = 1e-73 Identities = 156/351 (44%), Positives = 182/351 (51%), Gaps = 30/351 (8%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RG PG G PG G G PG G G G+PG PG G G QG+ G +G G G +GP Sbjct: 669 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 728 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGL------ 369 +G G G G DG G G+ G G G G PG G G PGP+G GA G+ Sbjct: 729 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 788 Query: 370 KGEKGE---PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGG 426 KGEKGE PG G+ G G G G G GE GP G KG AG G+PGP G GE+G Sbjct: 789 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 848 Query: 427 PGERGPRGTPGTRGPRGD---PGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGP 483 G G G PG +GP+G PG G G++G G G PG G+ GP GP+G RG GP Sbjct: 849 LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 908 Query: 484 PGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYP 543 G G +G G GPPG PG G +G GP GFPG G G PG +G G+P Sbjct: 909 TGKPGPKGTSGGDGPPGPPGERGPQGPQGPV--------GFPGPKGPPGPPGKDGLPGHP 960 Query: 544 GLKGD---EGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G +G+ +G+ G PG P GV G +G G GP G GH GPPGP Sbjct: 961 GQRGETGFQGKTGPPG-------PGGVVGPQGPTGETGPIGERGHPGPPGP 1004 Score = 266 bits (681), Expect = 6e-71 Identities = 165/398 (41%), Positives = 193/398 (48%), Gaps = 59/398 (14%) Query: 253 QPARGPPGL--RGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310 +PA PG+ G PG G G G PG +G G PG PGD GP G G+ G G G Sbjct: 442 EPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPP 501 Query: 311 GSR-------GPKGYKGE--------------------KGKRGIDGVDGVKGEMGYPGLP 343 G+ G G KG +G G G+ G G +G PG Sbjct: 502 GTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSS 561 Query: 344 GCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPP 403 G KG G G QGP G +G PG G G++G PGADG G PG G GD G G PG P Sbjct: 562 GAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLP 621 Query: 404 GEKGEAGDEGNPGPDGAPGE---RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPV 460 G+KG G+ G GP G PG+ RG GE GPRG PG GPRG G G G G+ G Sbjct: 622 GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 681 Query: 461 GVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTE 519 GV G PG G +GP+G G G G+ G +G PGP GP G PG G +G+ G AG G + Sbjct: 682 GVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 741 Query: 520 GFPGFP---------------------GYPGNRGAPGINGTKGYPGLKGDEGEAGDPG-- 556 G PG P GYPG RG G +G +G G KG++GE G PG Sbjct: 742 GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 801 Query: 557 DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGP---PGP 591 D RG G G RG +GP+GP G GP PGP Sbjct: 802 GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 839 Score = 246 bits (629), Expect = 6e-65 Identities = 139/295 (47%), Positives = 167/295 (56%), Gaps = 14/295 (4%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGE---KGSRGEKGS 312 +G PG G+PG GE G G GE+GE G+ G PG GP G +G G+ KG+ G G Sbjct: 1266 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1325 Query: 313 RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372 G G GE G G DGV G KGE G PG PG G G G GPPG +G PGA G +G Sbjct: 1326 PGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGR 1385 Query: 373 KGEPGADGEAGR---PGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGE 429 +GE GA GEAG PG +GP G +G G+PGP G +G G G G GA G+ G PG Sbjct: 1386 QGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGP 1445 Query: 430 RGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGA 489 GP G PG +G DPG +G++G G +G+ G PGE G G +G G +G PG++G Sbjct: 1446 MGPPGLPGLKG---DPGS---KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGD 1499 Query: 490 RGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPG 544 G PGPAGP G PG G G GP GN +G G G G+ G PG G+ G PG Sbjct: 1500 GGIPGPAGPLGPPGPPGLPGPQGPKGN--KGSTGPAGQKGDSGLPGPPGSPGPPG 1552 Score = 225 bits (573), Expect = 2e-58 Identities = 118/255 (46%), Positives = 138/255 (54%), Gaps = 9/255 (3%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGE----- 309 A GPPG +G PG +G +G PG G G+ G PG PG G G G KGE G G+ Sbjct: 1301 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1360 Query: 310 -KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFG 368 G GP G G++G G G +G +GE G G G +G PG G GP GP G PG G Sbjct: 1361 PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEG 1420 Query: 369 LKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPG 428 L+G G G G G G GP G G PG PG G+ G G++G+PG G G G G Sbjct: 1421 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG 1480 Query: 429 ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEG 488 E+G RG PGT +G PG G G G GP+G PG PG GP GPKG +G GP G +G Sbjct: 1481 EKGDRGLPGT---QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG 1537 Query: 489 ARGAPGPAGPPGDPG 503 G PGP G PG PG Sbjct: 1538 DSGLPGPPGSPGPPG 1552 Score = 213 bits (541), Expect = 1e-54 Identities = 151/380 (39%), Positives = 175/380 (46%), Gaps = 70/380 (18%) Query: 273 KPGLPGEKGEAGDPGRPGDLG----PVGYQGMKGEKGSRGE----------KGSRGPKGY 318 KP P E PG P + + G GEKG +GE +G GP G Sbjct: 404 KPTSP--PNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGP 461 Query: 319 KGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD-PGAFGLKGEKGEPG 377 G G G+ G G G+ G G PG G PG DG+ GPPG P +G G KG Sbjct: 462 AGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTI 521 Query: 378 ADGEA--------------GRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGE 423 + EA G PG G +G G G PG G KGE+GD G GP G G Sbjct: 522 SAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGP 581 Query: 424 RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGP 483 G G+ G RG PG G RG PGE G +GD+G +G G+PGD G +G RG +GP Sbjct: 582 PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGH------RGERGPQGP 635 Query: 484 PGSE------------GARGAPGPAGP------------PGDPGLMGERGEDGPAGN-GT 518 PG G RG PG AGP PG PG+ G G GP GN G Sbjct: 636 PGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGP 695 Query: 519 EGFPGFPGY---PGNRGAPGINGTKGYPGLKGDEGE---AGDPGDDNNDIAP--RGVKGA 570 +G PG PG PG +G PG G G PG KG +G+ AG PG D P G G Sbjct: 696 QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGE 755 Query: 571 KGYRGPEGPQGPPGHQGPPG 590 KG GP GPQGP G+ GP G Sbjct: 756 KGALGPPGPQGPIGYPGPRG 775 Score = 194 bits (493), Expect = 4e-49 Identities = 107/224 (47%), Positives = 126/224 (56%), Gaps = 21/224 (9%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP---VGYQGMKGEKGSRGEKGSR 313 G G+ GD G +G+ G+PG PG GEAG PG PG GP G +G +GEKG++GE G+ Sbjct: 1339 GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAE 1398 Query: 314 GPKGY------KGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAF 367 GP G +G GK G +G+ G+ G +G GLPG G DG GP GP G PG Sbjct: 1399 GPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ---DGPPGPMGPPGLPGLK 1455 Query: 368 ---GLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGER 424 G KGEKG PG G G PG G GD G PG G PG KG+ G G GP G PG Sbjct: 1456 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP 1515 Query: 425 GGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGE 468 G PG +GP+G G+ GP AG +GD G GP G PG PGE Sbjct: 1516 GLPGPQGPKGNKGSTGP------AGQKGDSGLPGPPGSPGPPGE 1553 Score = 157 bits (398), Expect = 4e-38 Identities = 99/238 (41%), Positives = 114/238 (47%), Gaps = 31/238 (13%) Query: 365 GAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE--PGPPGEKGEAGDEGNPGPDGAPG 422 GA+G KG+KGEP +PG GPPG G AG G PG G G Sbjct: 432 GAYGEKGQKGEPAVV----------------EPGMLVEGPPGPAGPAGIMGPPGLQGPTG 475 Query: 423 ERGGPGERGPRGTPGTRGPRGDPGEAGPQ-------GDQGREGPVGVPGDPGEAGPIGPK 475 G PG+RGP G PG G G PG G G G +GP + +A I + Sbjct: 476 PPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPT-ISAQEAQAQAILQQ 534 Query: 476 GYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAP 534 GPPG G G PGP G PG G GE G+ GP G G +G PG G PG RG P Sbjct: 535 ARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRP 594 Query: 535 GINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592 G +G +G PG + G GD G D P G KG +G RGP+GP GPPG G G D Sbjct: 595 GADGGRGMPG---EPGAKGDRGFDGLPGLP-GDKGHRGERGPQGPPGPPGDDGMRGED 648 Score = 103 bits (258), Expect = 6e-22 Identities = 61/141 (43%), Positives = 73/141 (51%), Gaps = 24/141 (17%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GPPG G PG G +G PG KGE G PG G +GP G QG KG++G G +GS Sbjct: 1441 GPPGPMGPPGLPGLKGDPG---SKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGS---- 1493 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376 G KG+ G PG G G PG G+ GP GPKG+ G+ G G+KG+ Sbjct: 1494 --------------PGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDS 1539 Query: 377 GADGEAGRPGSSGPSGDEGQP 397 G G PGS GP G+ QP Sbjct: 1540 GLPGP---PGSPGPPGEVIQP 1557 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 303 bits (775), Expect = 7e-82 Identities = 166/357 (46%), Positives = 196/357 (54%), Gaps = 29/357 (8%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G PG+ G G G RG+ G+ G+KG+ G G PG GP+G QG+ G G +GE G GP Sbjct: 1120 GAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPM 1179 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGC------KGSPGFDGIQGPPGPKGDPGAFGLK 370 G G G RG G +G G G PG G KG PG G GPPG G G G + Sbjct: 1180 GPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGER 1239 Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQ---------PGEPGPPGEKGEAGDEG---NPGPD 418 GEKGE G G AG PG+ GP GD+G PG+PGPPGE G AG +G + G D Sbjct: 1240 GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGED 1299 Query: 419 GAPGERGGPG---ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475 G PG+ G PG E GP G PG RGP G G G QG++G +G G G PG+ GP+GP+ Sbjct: 1300 GDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQ 1359 Query: 476 GYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAP 534 G G PG EG RG PGP G G PG G+ G GP G G G G PG G +G P Sbjct: 1360 G---PAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHP 1416 Query: 535 GINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G+ G G PG +G++G+ G PG + G KG G GP GP GPPG G PGP Sbjct: 1417 GLIGLIGPPGEQGEKGDRGLPGTQGSP----GAKGDGGIPGPAGPLGPPGPPGLPGP 1469 Score = 296 bits (758), Expect = 7e-80 Identities = 170/376 (45%), Positives = 199/376 (52%), Gaps = 47/376 (12%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 +G PGL G PG +G G PG G+ GE G G PG GP+GY G +G KG+ G +G +G Sbjct: 678 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 737 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375 KG KGE G G G G+KG+ G G G +G G +G +G GP GDPG G GEKG+ Sbjct: 738 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 797 Query: 376 PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP---------GPDGAPGERGG 426 G G G PG GP G G PG PG GEKG G G P GP G+ G RG Sbjct: 798 LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 857 Query: 427 PGERGPRGTPGTRGPRGDPGEAGPQGDQGR---EGPVGVPGDP----------------- 466 G+ GP+GT G GP G PGE GPQG QG GP G PG P Sbjct: 858 TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGF 917 Query: 467 -GEAGPIGPKGYRGDEGPPGSE---GARGAPGPAGPPGDPGLMGERGEDGPAG------- 515 G+ GP GP G G +GP G G RG PGP GPPG+ GL G G++G G Sbjct: 918 QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGI 977 Query: 516 NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRG 575 +G +G G G+PG RG P G +G PGLKG EG G PG + G +G+ G G Sbjct: 978 SGKDGPAGLRGFPGERGLP---GAQGAPGLKGGEGPQGPPG----PVGSPGERGSAGTAG 1030 Query: 576 PEGPQGPPGHQGPPGP 591 P G G PG QGPPGP Sbjct: 1031 PIGLPGRPGPQGPPGP 1046 Score = 295 bits (754), Expect = 2e-79 Identities = 163/357 (45%), Positives = 197/357 (55%), Gaps = 21/357 (5%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G PG RG+ GF+G+ G PG G G G G G +G G+ G G G +G G+ G + Sbjct: 907 GHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKE 966 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPG---LPGCKGSPGF---DGIQGPPGPKGDPGAFGLK 370 G KG+ G +GI G DG G G+PG LPG +G+PG +G QGPPGP G PG G Sbjct: 967 GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA 1026 Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGN---PGPDGAPGERGGP 427 G G G G G G GP+G++G PGE GP G G G +G PGP G G G Sbjct: 1027 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGED 1086 Query: 428 GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487 G++G G PG +G +GD GE GP G G +GPVG PG G G GP+G +G G G E Sbjct: 1087 GDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDE 1146 Query: 488 GARGAPGPAGP------PGDPGLMGERGEDGPAG----NGTEGFPGFPGYPGNRGAPGIN 537 GARG PGP GP PG PG GE G+ GP G G G G G G +G PG Sbjct: 1147 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV 1206 Query: 538 GTKGYPGLKGDEGEAGDPG--DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592 G+ G G KG+ GEAG+PG + P+G +G KG GP G GPPG +GPPG D Sbjct: 1207 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDD 1263 Score = 294 bits (752), Expect = 3e-79 Identities = 157/351 (44%), Positives = 190/351 (54%), Gaps = 17/351 (4%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G PG RG PG +G RG PG PG KG+ G G PG G G++G +G +G G G G + Sbjct: 535 GKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMR 594 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD---------PGAF 367 G GE G RG+ G G +G +G G PG G PG G+ GPPGPKG+ PG Sbjct: 595 GEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQ 654 Query: 368 GLKGEKGEPGADGEAGRPGSSGPSGDEGQ---PGEPGP---PGEKGEAGDEGNPGPDGAP 421 G G +G PG G G PG GP G G PG GP PG++G++G++G GP G Sbjct: 655 GNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQ 714 Query: 422 GERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE 481 G G PG RG +G G RG +G GE G G G +G +G+ GD GE G IGP+G G E Sbjct: 715 GPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPE 774 Query: 482 GPPGSEGARGAPGPAGPPGDPGLMGERGEDG-PAGNGTEGFPGFPGYPGNRGAPGINGTK 540 GP G G G PGP+G G+ G +G G G P G +G GFPG+PG G G G Sbjct: 775 GPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA 834 Query: 541 GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G PG +G G G P P G G KG G +GP GPPG +GP GP Sbjct: 835 GKPGPRGQRGPTG-PRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGP 884 Score = 291 bits (744), Expect = 3e-78 Identities = 176/376 (46%), Positives = 204/376 (54%), Gaps = 44/376 (11%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGR---PGDLGPVGYQGMKGEKGSRGEKG 311 A+G PGL+G G +G G G PGE+G AG G PG GP G G GEKG+ GEKG Sbjct: 998 AQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG 1057 Query: 312 SRGPKGYKGEKGKRGI---------DGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKG 362 +GP G G +G G+ G DG KGE+G PG G KG G +G GPPG +G Sbjct: 1058 PQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQG 1117 Query: 363 DPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE---------PGPPGEKGEAGDEG 413 GA G+ G GEPG G+ G G G G G PG PGPPGEKGE GD G Sbjct: 1118 PVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVG 1177 Query: 414 NPGPDGAPGERG--GP-GERGPRGTPGT------RGPRGDPGEA---GPQGDQGREGPVG 461 GP G PG RG GP G GP+G PG+ G +G+PGEA GP G+ G GP G Sbjct: 1178 PMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKG 1237 Query: 462 VPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGE---RGEDGPAGN-G 517 G+ GEAGP G G G +GPPG +G +G PGP G PGDPG GE G+DG G+ G Sbjct: 1238 ERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKG 1297 Query: 518 TEGFPGFPGYP---GNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYR 574 +G PG PG P G G PG G +G PG G EG G+ G G +G G Sbjct: 1298 EDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE----AGAEGPPGKT 1353 Query: 575 GPEGPQGPPGHQGPPG 590 GP GPQGP G GP G Sbjct: 1354 GPVGPQGPAGKPGPEG 1369 Score = 289 bits (739), Expect = 1e-77 Identities = 162/348 (46%), Positives = 187/348 (53%), Gaps = 20/348 (5%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLG---PVGYQGMKGEKGSRGEKGSR 313 G PG +G PG GE+G PG G +G AG G G +G P G G GE G +GE G Sbjct: 1036 GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEP 1095 Query: 314 GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373 G KG KG+KG+ G G G++G +G PG+ G G PG G QG G KGD GA G G Sbjct: 1096 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPP 1155 Query: 374 GEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPR 433 G G G G PG G +GD G G PGPPG +G G G GP G PG G G G + Sbjct: 1156 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1215 Query: 434 GTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAP 493 G PG G G PGEAG G +G G G G PG AGP G KG GD+GP G+ G G P Sbjct: 1216 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFP 1275 Query: 494 GPAGPPGDP------GLMGERGEDGPAGN----GTEGFPGFPGYPGNRGAPGINGTKGYP 543 G GPPG+P G+ G++GEDG G G G G PG PG RG PG G +G Sbjct: 1276 GDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ 1335 Query: 544 GLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G KG +GEAG G P G G G +GP G GP G +G PGP Sbjct: 1336 GEKGAKGEAGAEG-------PPGKTGPVGPQGPAGKPGPEGLRGIPGP 1376 Score = 288 bits (737), Expect = 2e-77 Identities = 166/364 (45%), Positives = 195/364 (53%), Gaps = 31/364 (8%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP------VGYQGMKGEKGSRGE 309 RGP G RG G G GKPG G G G PG PG+ GP VG+ G KG G G+ Sbjct: 843 RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGK 902 Query: 310 KGSRGPKGYKGE---KGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366 G G G +GE +GK G G GV G G G G G G G GPPG +G PGA Sbjct: 903 DGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGA 962 Query: 367 FGLKGEKGEPGADGEAGRPGSSGPSG---DEGQPGEPGPPGEKGEAGDEGNPGPDGAPGE 423 G +G KG+PG G +G+ G +G G + G PG G PG KG G +G PGP G+PGE Sbjct: 963 AGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGE 1022 Query: 424 RGG---------PGERGPRGTPGTRGPRGDPGEAGPQGDQGR---EGPVGVPGDPGEAGP 471 RG PG GP+G PG G +G PGE GPQG GR +GPVG+PG G AG Sbjct: 1023 RGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1082 Query: 472 IGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNR 531 G G +G+ G PG +G++G G GPPG PGL G G G AG +G PG G G Sbjct: 1083 PGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG--DGEPGPRGQQGMF 1140 Query: 532 GAPGINGTKGYPGLKGDEGEAGDPG-----DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQ 586 G G G +G+PG G G G PG +N D+ P G G G RGP+GP G G Q Sbjct: 1141 GQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1200 Query: 587 GPPG 590 GPPG Sbjct: 1201 GPPG 1204 Score = 286 bits (732), Expect = 7e-77 Identities = 170/393 (43%), Positives = 194/393 (49%), Gaps = 63/393 (16%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RGPPG G G G G PG G KGE+GDPG G G G G G+ G RG G+ G Sbjct: 489 RGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGG 548 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375 +G GE G +G G DG+ PGLPG KG G G QGPPGP GD G G GE G Sbjct: 549 RGMPGEPGAKGDRGFDGL------PGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP 602 Query: 376 PGADGEAGRPGSSGPSGDEGQPGEP------GPPGEKGEAGDEGNPGP---DGAPGERGG 426 G GEAG G GP G G PG+P GPPG KG G +G PGP G PG +G Sbjct: 603 RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 662 Query: 427 PGERGPRGTPGTRGPRGDPGEA------GPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480 PG +GP G PG +GP+G PG A GP G G+EG G G G GP GP GY G Sbjct: 663 PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGP 722 Query: 481 EGPPGSEGARGAPGPAGPPGDPGL------------------MGERGEDGPAG------- 515 G G++G RG G G G+ G +G RGEDGP G Sbjct: 723 RGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP 782 Query: 516 ------------NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGE---AGDPG--DD 558 G G PG PGYPG +G G G G+PG G++G AG PG Sbjct: 783 TGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQ 842 Query: 559 NNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 PRG +GA+G G GP+G G GPPGP Sbjct: 843 RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGP 875 Score = 284 bits (727), Expect = 3e-76 Identities = 157/346 (45%), Positives = 187/346 (54%), Gaps = 21/346 (6%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314 A G GL+G G +GE G PG G+ G GD G G +GP G G +G KG G G G Sbjct: 728 ADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 787 Query: 315 PKGYKGEKGKRGIDGVDGV------KGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFG 368 P G GEKGK G+ G+ G KG G+PG PG G G G+ G PGP+G G G Sbjct: 788 PSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTG 847 Query: 369 LKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPG 428 +G +G A G G+PG G SG +G PG PPGE+G G + GP G PG +G PG Sbjct: 848 PRGSRG---ARGPTGKPGPKGTSGGDGPPG---PPGERGPQGPQ---GPVGFPGPKGPPG 898 Query: 429 ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEG 488 G G PG G RG+ G G G G G VG G GE GPIG +G+ G GPPG +G Sbjct: 899 PPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQG 958 Query: 489 ARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGD 548 GA G G GDPG G G+DGPA G GFPG G PG +GAPG+ G +G G G Sbjct: 959 LPGAAGKEGAKGDPGPQGISGKDGPA--GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGP 1016 Query: 549 EGEAGDPGDDNNDIAPRGVKGAKGYRGPEGP---QGPPGHQGPPGP 591 G G+ G P G+ G G +GP GP +G PG +GP GP Sbjct: 1017 VGSPGERGSAGT-AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGP 1061 Score = 284 bits (726), Expect = 3e-76 Identities = 157/342 (45%), Positives = 188/342 (54%), Gaps = 13/342 (3%) Query: 257 GPPGLRGDPGFEGERGKPGLPG------EKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310 G PG G G +G+ G PGLPG KG G PG PG G G +G+ G+ G RG++ Sbjct: 784 GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 843 Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370 G GP+G +G +G G G G G G PG PG +G G G G PGPKG PG G Sbjct: 844 GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 903 Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGER 430 G G PG GE G G +GP G G G GP GE G G+ G+PGP G PGE+G PG Sbjct: 904 GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 963 Query: 431 GPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGAR 490 G G G GP+G G+ GP G +G G G+PG G G G +G +G GP GS G R Sbjct: 964 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1023 Query: 491 GAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEG 550 G+ G AGP G PG G +G GPAG G PG G +G G +G +G GL G G Sbjct: 1024 GSAGTAGPIGLPGRPGPQGPPGPAGE-----KGAPGEKGPQGPAGRDGVQGPVGLPGPAG 1078 Query: 551 EAGDPGDDNN--DIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 AG PG+D + +I G KG+KG +G GP GPPG QGP G Sbjct: 1079 PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG 1120 Score = 284 bits (726), Expect = 3e-76 Identities = 164/365 (44%), Positives = 189/365 (51%), Gaps = 41/365 (11%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGD------PGRPGDLGPVGYQGMKGEKGSRGEK 310 G G G PG G +G PG PGEKGE GD PG PG GP G G G +G G Sbjct: 1147 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV 1206 Query: 311 GSRGPKGYKGEKGKRG---------IDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361 GS G G KGE G+ G + G G +GE G G PG G PG G G GPK Sbjct: 1207 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK 1266 Query: 362 GDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP---GPD 418 G+PG G G+ G PG G AG+ G G G++G PG+PGPPG GEAG G P GP Sbjct: 1267 GNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPP 1326 Query: 419 GAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYR 478 GA G G GE+G +G G GP G G GPQG G+ GP G+ G PG Sbjct: 1327 GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV--------- 1377 Query: 479 GDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGIN 537 G++G PG+ G G PGP GPPG PGL G+ G G G+ G G G PG G +G G+ Sbjct: 1378 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1437 Query: 538 GTKGYPGLKGD------EGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQ------GPPGH 585 GT+G PG KGD G G PG P+G KG KG GP G + GPPG Sbjct: 1438 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLP-GPQGPKGNKGSTGPAGQKGDSGLPGPPGS 1496 Query: 586 QGPPG 590 GPPG Sbjct: 1497 PGPPG 1501 Score = 282 bits (722), Expect = 1e-75 Identities = 168/378 (44%), Positives = 193/378 (51%), Gaps = 44/378 (11%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G G G PG GE+G PG G++G GDPG G G G G++G G RG G++G Sbjct: 943 GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1002 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376 G KG +G +G G G GE G G G G PG G QGPPGP G+ GA G KG +G Sbjct: 1003 GLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPA 1062 Query: 377 GAD---------GEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPD------GAP 421 G D G AG GS G GD+G+ GEPG G KG+ G+ G PGP GAP Sbjct: 1063 GRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAP 1122 Query: 422 GERGGPGERGPRGTPGTRGPRGD------------------PGEAGPQGDQGREGPVGVP 463 G GG GE GPRG G G +GD PG G +G+ G GP+G P Sbjct: 1123 GIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1182 Query: 464 GDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGD---PGLMGERGEDGPAG----N 516 G PG GP GP G G +GPPGS G+ G G G PG+ PG GE G GP G Sbjct: 1183 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1242 Query: 517 GTEGFPGFPGYPGNRGAPGINGTKGYP---GLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573 G G PG G PG +G PG +G KG P G GD G G+PG D G KG G Sbjct: 1243 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQD-GVGGDKGEDGD 1301 Query: 574 RGPEGPQGPPGHQGPPGP 591 G GP GP G GPPGP Sbjct: 1302 PGQPGPPGPSGEAGPPGP 1319 Score = 281 bits (720), Expect = 2e-75 Identities = 165/374 (44%), Positives = 196/374 (52%), Gaps = 41/374 (10%) Query: 257 GPPGLRGDPG---FEGERGKPGLPGEKGEAGDPGR---PGDLGPVGYQGMKGEKGSRGEK 310 GPPG +G+PG G +G G PGEKG G PG PG GP G+ G +G+ G +G Sbjct: 649 GPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL 708 Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370 G GP+G G G RG+ G DGV+G G G G G PGF G G G +G+ G G + Sbjct: 709 GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 768 Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQ------PGEPGPPGEKGEAGDEGNPGPDGAPGER 424 GE G G G AG G GPSG G+ PG PG PG +G G G PG GA GE+ Sbjct: 769 GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 828 Query: 425 G--------GP-GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475 G GP G+RGP G G+RG RG G+ GP+G G +GP G PG+ G GP GP Sbjct: 829 GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPV 888 Query: 476 GYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-------------NGTEGFP 522 G+ G +GPPG G G PG G G+ G G+ G GP G G G P Sbjct: 889 GFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHP 948 Query: 523 GFPGYPGNRGAPGI---NGTKGYP---GLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGP 576 G PG PG +G PG G KG P G+ G +G AG G P G +GA G +G Sbjct: 949 GPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLP-GAQGAPGLKGG 1007 Query: 577 EGPQGPPGHQGPPG 590 EGPQGPPG G PG Sbjct: 1008 EGPQGPPGPVGSPG 1021 Score = 278 bits (710), Expect = 2e-74 Identities = 159/350 (45%), Positives = 190/350 (54%), Gaps = 23/350 (6%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G PGL GD G GERG G PG G+ G G G++GP +G+ GE G RG G RG Sbjct: 565 GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP---RGLPGEAGPRGLLGPRGTP 621 Query: 317 GYKGEKGKRGIDGVDGVKGEMG---YPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373 G G+ G G+DG G KG MG PG PG +G+PG G+ GP GP G PG G +G+ Sbjct: 622 GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP 681 Query: 374 GE---PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGER 430 G PGADG G PG G SG++G G PGP G G G G G DG G +G GE+ Sbjct: 682 GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK 741 Query: 431 GPRGTPG------TRGPRGDPGEAGPQGDQGREGP---VGVPGDPGEAGPIGPKGYRGDE 481 G G PG +G RG+ G+ GP+G+ G EGP G GDPG +G G KG G Sbjct: 742 GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP 801 Query: 482 GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTK 540 G PG G +G G G PG PG GE+G G AG G G G G G+RGA G G Sbjct: 802 GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKP 861 Query: 541 GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G G G +G G PG+ P+G +G G+ GP+GP GPPG G PG Sbjct: 862 GPKGTSGGDGPPGPPGER----GPQGPQGPVGFPGPKGPPGPPGKDGLPG 907 Score = 277 bits (709), Expect = 3e-74 Identities = 157/344 (45%), Positives = 182/344 (52%), Gaps = 21/344 (6%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RGP G +G GF G +G PG PG+ G PG PG G G+QG G G G G +GP Sbjct: 879 RGPQGPQGPVGFPGPKGPPGPPGKDGL---PGHPGQRGETGFQGKTGPPGPGGVVGPQGP 935 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375 G G G+RG G G GE G PG G +G+ G G QG G G G G GE+G Sbjct: 936 TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL 995 Query: 376 PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD---EGNPGPDGAPG---ERGGPGE 429 PGA G G G GP G G G PG G G AG G PGP G PG E+G PGE Sbjct: 996 PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1055 Query: 430 RGPRGTPG---TRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGS 486 +GP+G G +GP G PG AGP G G +G G G+PG+ G G KG G GPPG Sbjct: 1056 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1115 Query: 487 EGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLK 546 +G GAPG AG G+PG G++G G G+ EG GFPG PG G G+ G G G Sbjct: 1116 QGPVGAPGIAGGDGEPGPRGQQGMFGQKGD--EGARGFPGPPGPIGLQGLPGPPGEKGEN 1173 Query: 547 GDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 GD G G PG P G +G +G G +GPQGPPG G G Sbjct: 1174 GDVGPMGPPG-------PPGPRGPQGPNGADGPQGPPGSVGSVG 1210 Score = 276 bits (705), Expect = 9e-74 Identities = 161/369 (43%), Positives = 187/369 (50%), Gaps = 36/369 (9%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RG PG +G PG +G G G PG G G+ G G GP+G + G G +G G G Sbjct: 993 RGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIG---LPGRPGPQGPPGPAGE 1049 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGP---PGPKGDPGAFGLKGE 372 KG GEKG +G G DGV+G +G PG G GSPG DG +G PG KG G G G Sbjct: 1050 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP 1109 Query: 373 KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGP 432 G PG G G PG +G G+ G G+ G G+KG+ G G PGP G G +G PG G Sbjct: 1110 PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1169 Query: 433 RGTPGTRGPRGDPGEAGPQGDQ---GREGPVGVP------------GDPGEAGPIGPKGY 477 +G G GP G PG GP+G Q G +GP G P G+PGEAG GP G Sbjct: 1170 KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1229 Query: 478 RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGI 536 G GP G G +G GP G G PG G G+DGP GN G GFPG PG PG G G Sbjct: 1230 AGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQ 1289 Query: 537 NGT---------KGYPGLKGDEGEAGDPGDDNNDIAP-----RGVKGAKGYRGPEGPQGP 582 +G G PG G GEAG PG P G +G KG +G G +GP Sbjct: 1290 DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP 1349 Query: 583 PGHQGPPGP 591 PG GP GP Sbjct: 1350 PGKTGPVGP 1358 Score = 275 bits (704), Expect = 1e-73 Identities = 156/351 (44%), Positives = 182/351 (51%), Gaps = 30/351 (8%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RG PG G PG G G PG G G G+PG PG G G QG+ G +G G G +GP Sbjct: 618 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 677 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGL------ 369 +G G G G DG G G+ G G G G PG G G PGP+G GA G+ Sbjct: 678 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 737 Query: 370 KGEKGE---PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGG 426 KGEKGE PG G+ G G G G G GE GP G KG AG G+PGP G GE+G Sbjct: 738 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 797 Query: 427 PGERGPRGTPGTRGPRGD---PGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGP 483 G G G PG +GP+G PG G G++G G G PG G+ GP GP+G RG GP Sbjct: 798 LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 857 Query: 484 PGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYP 543 G G +G G GPPG PG G +G GP GFPG G G PG +G G+P Sbjct: 858 TGKPGPKGTSGGDGPPGPPGERGPQGPQGPV--------GFPGPKGPPGPPGKDGLPGHP 909 Query: 544 GLKGD---EGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G +G+ +G+ G PG P GV G +G G GP G GH GPPGP Sbjct: 910 GQRGETGFQGKTGPPG-------PGGVVGPQGPTGETGPIGERGHPGPPGP 953 Score = 266 bits (681), Expect = 6e-71 Identities = 165/398 (41%), Positives = 193/398 (48%), Gaps = 59/398 (14%) Query: 253 QPARGPPGL--RGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310 +PA PG+ G PG G G G PG +G G PG PGD GP G G+ G G G Sbjct: 391 EPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPP 450 Query: 311 GSR-------GPKGYKGE--------------------KGKRGIDGVDGVKGEMGYPGLP 343 G+ G G KG +G G G+ G G +G PG Sbjct: 451 GTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSS 510 Query: 344 GCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPP 403 G KG G G QGP G +G PG G G++G PGADG G PG G GD G G PG P Sbjct: 511 GAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLP 570 Query: 404 GEKGEAGDEGNPGPDGAPGE---RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPV 460 G+KG G+ G GP G PG+ RG GE GPRG PG GPRG G G G G+ G Sbjct: 571 GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 630 Query: 461 GVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTE 519 GV G PG G +GP+G G G G+ G +G PGP GP G PG G +G+ G AG G + Sbjct: 631 GVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 690 Query: 520 GFPGFP---------------------GYPGNRGAPGINGTKGYPGLKGDEGEAGDPG-- 556 G PG P GYPG RG G +G +G G KG++GE G PG Sbjct: 691 GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 750 Query: 557 DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGP---PGP 591 D RG G G RG +GP+GP G GP PGP Sbjct: 751 GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 788 Score = 246 bits (629), Expect = 6e-65 Identities = 139/295 (47%), Positives = 167/295 (56%), Gaps = 14/295 (4%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGE---KGSRGEKGS 312 +G PG G+PG GE G G GE+GE G+ G PG GP G +G G+ KG+ G G Sbjct: 1215 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1274 Query: 313 RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372 G G GE G G DGV G KGE G PG PG G G G GPPG +G PGA G +G Sbjct: 1275 PGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGR 1334 Query: 373 KGEPGADGEAGR---PGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGE 429 +GE GA GEAG PG +GP G +G G+PGP G +G G G G GA G+ G PG Sbjct: 1335 QGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGP 1394 Query: 430 RGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGA 489 GP G PG +G DPG +G++G G +G+ G PGE G G +G G +G PG++G Sbjct: 1395 MGPPGLPGLKG---DPGS---KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGD 1448 Query: 490 RGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPG 544 G PGPAGP G PG G G GP GN +G G G G+ G PG G+ G PG Sbjct: 1449 GGIPGPAGPLGPPGPPGLPGPQGPKGN--KGSTGPAGQKGDSGLPGPPGSPGPPG 1501 Score = 225 bits (573), Expect = 2e-58 Identities = 118/255 (46%), Positives = 138/255 (54%), Gaps = 9/255 (3%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGE----- 309 A GPPG +G PG +G +G PG G G+ G PG PG G G G KGE G G+ Sbjct: 1250 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1309 Query: 310 -KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFG 368 G GP G G++G G G +G +GE G G G +G PG G GP GP G PG G Sbjct: 1310 PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEG 1369 Query: 369 LKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPG 428 L+G G G G G G GP G G PG PG G+ G G++G+PG G G G G Sbjct: 1370 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG 1429 Query: 429 ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEG 488 E+G RG PGT +G PG G G G GP+G PG PG GP GPKG +G GP G +G Sbjct: 1430 EKGDRGLPGT---QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG 1486 Query: 489 ARGAPGPAGPPGDPG 503 G PGP G PG PG Sbjct: 1487 DSGLPGPPGSPGPPG 1501 Score = 213 bits (541), Expect = 1e-54 Identities = 151/380 (39%), Positives = 175/380 (46%), Gaps = 70/380 (18%) Query: 273 KPGLPGEKGEAGDPGRPGDLG----PVGYQGMKGEKGSRGE----------KGSRGPKGY 318 KP P E PG P + + G GEKG +GE +G GP G Sbjct: 353 KPTSP--PNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGP 410 Query: 319 KGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD-PGAFGLKGEKGEPG 377 G G G+ G G G+ G G PG G PG DG+ GPPG P +G G KG Sbjct: 411 AGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTI 470 Query: 378 ADGEA--------------GRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGE 423 + EA G PG G +G G G PG G KGE+GD G GP G G Sbjct: 471 SAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGP 530 Query: 424 RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGP 483 G G+ G RG PG G RG PGE G +GD+G +G G+PGD G +G RG +GP Sbjct: 531 PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGH------RGERGPQGP 584 Query: 484 PGSE------------GARGAPGPAGP------------PGDPGLMGERGEDGPAGN-GT 518 PG G RG PG AGP PG PG+ G G GP GN G Sbjct: 585 PGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGP 644 Query: 519 EGFPGFPGY---PGNRGAPGINGTKGYPGLKGDEGE---AGDPGDDNNDIAP--RGVKGA 570 +G PG PG PG +G PG G G PG KG +G+ AG PG D P G G Sbjct: 645 QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGE 704 Query: 571 KGYRGPEGPQGPPGHQGPPG 590 KG GP GPQGP G+ GP G Sbjct: 705 KGALGPPGPQGPIGYPGPRG 724 Score = 194 bits (493), Expect = 4e-49 Identities = 107/224 (47%), Positives = 126/224 (56%), Gaps = 21/224 (9%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP---VGYQGMKGEKGSRGEKGSR 313 G G+ GD G +G+ G+PG PG GEAG PG PG GP G +G +GEKG++GE G+ Sbjct: 1288 GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAE 1347 Query: 314 GPKGY------KGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAF 367 GP G +G GK G +G+ G+ G +G GLPG G DG GP GP G PG Sbjct: 1348 GPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ---DGPPGPMGPPGLPGLK 1404 Query: 368 ---GLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGER 424 G KGEKG PG G G PG G GD G PG G PG KG+ G G GP G PG Sbjct: 1405 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP 1464 Query: 425 GGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGE 468 G PG +GP+G G+ GP AG +GD G GP G PG PGE Sbjct: 1465 GLPGPQGPKGNKGSTGP------AGQKGDSGLPGPPGSPGPPGE 1502 Score = 157 bits (398), Expect = 4e-38 Identities = 99/238 (41%), Positives = 114/238 (47%), Gaps = 31/238 (13%) Query: 365 GAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE--PGPPGEKGEAGDEGNPGPDGAPG 422 GA+G KG+KGEP +PG GPPG G AG G PG G G Sbjct: 381 GAYGEKGQKGEPAVV----------------EPGMLVEGPPGPAGPAGIMGPPGLQGPTG 424 Query: 423 ERGGPGERGPRGTPGTRGPRGDPGEAGPQ-------GDQGREGPVGVPGDPGEAGPIGPK 475 G PG+RGP G PG G G PG G G G +GP + +A I + Sbjct: 425 PPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPT-ISAQEAQAQAILQQ 483 Query: 476 GYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAP 534 GPPG G G PGP G PG G GE G+ GP G G +G PG G PG RG P Sbjct: 484 ARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRP 543 Query: 535 GINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592 G +G +G PG + G GD G D P G KG +G RGP+GP GPPG G G D Sbjct: 544 GADGGRGMPG---EPGAKGDRGFDGLPGLP-GDKGHRGERGPQGPPGPPGDDGMRGED 597 Score = 103 bits (258), Expect = 6e-22 Identities = 61/141 (43%), Positives = 73/141 (51%), Gaps = 24/141 (17%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GPPG G PG G +G PG KGE G PG G +GP G QG KG++G G +GS Sbjct: 1390 GPPGPMGPPGLPGLKGDPG---SKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGS---- 1442 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376 G KG+ G PG G G PG G+ GP GPKG+ G+ G G+KG+ Sbjct: 1443 --------------PGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDS 1488 Query: 377 GADGEAGRPGSSGPSGDEGQP 397 G G PGS GP G+ QP Sbjct: 1489 GLPGP---PGSPGPPGEVIQP 1506 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 303 bits (775), Expect = 7e-82 Identities = 166/357 (46%), Positives = 196/357 (54%), Gaps = 29/357 (8%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G PG+ G G G RG+ G+ G+KG+ G G PG GP+G QG+ G G +GE G GP Sbjct: 1159 GAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPM 1218 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGC------KGSPGFDGIQGPPGPKGDPGAFGLK 370 G G G RG G +G G G PG G KG PG G GPPG G G G + Sbjct: 1219 GPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGER 1278 Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQ---------PGEPGPPGEKGEAGDEG---NPGPD 418 GEKGE G G AG PG+ GP GD+G PG+PGPPGE G AG +G + G D Sbjct: 1279 GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGED 1338 Query: 419 GAPGERGGPG---ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475 G PG+ G PG E GP G PG RGP G G G QG++G +G G G PG+ GP+GP+ Sbjct: 1339 GDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQ 1398 Query: 476 GYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAP 534 G G PG EG RG PGP G G PG G+ G GP G G G G PG G +G P Sbjct: 1399 G---PAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHP 1455 Query: 535 GINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G+ G G PG +G++G+ G PG + G KG G GP GP GPPG G PGP Sbjct: 1456 GLIGLIGPPGEQGEKGDRGLPGTQGSP----GAKGDGGIPGPAGPLGPPGPPGLPGP 1508 Score = 296 bits (758), Expect = 7e-80 Identities = 170/376 (45%), Positives = 199/376 (52%), Gaps = 47/376 (12%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 +G PGL G PG +G G PG G+ GE G G PG GP+GY G +G KG+ G +G +G Sbjct: 717 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 776 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375 KG KGE G G G G+KG+ G G G +G G +G +G GP GDPG G GEKG+ Sbjct: 777 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 836 Query: 376 PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP---------GPDGAPGERGG 426 G G G PG GP G G PG PG GEKG G G P GP G+ G RG Sbjct: 837 LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 896 Query: 427 PGERGPRGTPGTRGPRGDPGEAGPQGDQGR---EGPVGVPGDP----------------- 466 G+ GP+GT G GP G PGE GPQG QG GP G PG P Sbjct: 897 TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGF 956 Query: 467 -GEAGPIGPKGYRGDEGPPGSE---GARGAPGPAGPPGDPGLMGERGEDGPAG------- 515 G+ GP GP G G +GP G G RG PGP GPPG+ GL G G++G G Sbjct: 957 QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGI 1016 Query: 516 NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRG 575 +G +G G G+PG RG P G +G PGLKG EG G PG + G +G+ G G Sbjct: 1017 SGKDGPAGLRGFPGERGLP---GAQGAPGLKGGEGPQGPPG----PVGSPGERGSAGTAG 1069 Query: 576 PEGPQGPPGHQGPPGP 591 P G G PG QGPPGP Sbjct: 1070 PIGLPGRPGPQGPPGP 1085 Score = 295 bits (754), Expect = 2e-79 Identities = 163/357 (45%), Positives = 197/357 (55%), Gaps = 21/357 (5%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G PG RG+ GF+G+ G PG G G G G G +G G+ G G G +G G+ G + Sbjct: 946 GHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKE 1005 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPG---LPGCKGSPGF---DGIQGPPGPKGDPGAFGLK 370 G KG+ G +GI G DG G G+PG LPG +G+PG +G QGPPGP G PG G Sbjct: 1006 GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA 1065 Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGN---PGPDGAPGERGGP 427 G G G G G G GP+G++G PGE GP G G G +G PGP G G G Sbjct: 1066 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGED 1125 Query: 428 GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487 G++G G PG +G +GD GE GP G G +GPVG PG G G GP+G +G G G E Sbjct: 1126 GDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDE 1185 Query: 488 GARGAPGPAGP------PGDPGLMGERGEDGPAG----NGTEGFPGFPGYPGNRGAPGIN 537 GARG PGP GP PG PG GE G+ GP G G G G G G +G PG Sbjct: 1186 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV 1245 Query: 538 GTKGYPGLKGDEGEAGDPG--DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592 G+ G G KG+ GEAG+PG + P+G +G KG GP G GPPG +GPPG D Sbjct: 1246 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDD 1302 Score = 294 bits (752), Expect = 3e-79 Identities = 157/351 (44%), Positives = 190/351 (54%), Gaps = 17/351 (4%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G PG RG PG +G RG PG PG KG+ G G PG G G++G +G +G G G G + Sbjct: 574 GKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMR 633 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD---------PGAF 367 G GE G RG+ G G +G +G G PG G PG G+ GPPGPKG+ PG Sbjct: 634 GEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQ 693 Query: 368 GLKGEKGEPGADGEAGRPGSSGPSGDEGQ---PGEPGP---PGEKGEAGDEGNPGPDGAP 421 G G +G PG G G PG GP G G PG GP PG++G++G++G GP G Sbjct: 694 GNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQ 753 Query: 422 GERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE 481 G G PG RG +G G RG +G GE G G G +G +G+ GD GE G IGP+G G E Sbjct: 754 GPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPE 813 Query: 482 GPPGSEGARGAPGPAGPPGDPGLMGERGEDG-PAGNGTEGFPGFPGYPGNRGAPGINGTK 540 GP G G G PGP+G G+ G +G G G P G +G GFPG+PG G G G Sbjct: 814 GPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA 873 Query: 541 GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G PG +G G G P P G G KG G +GP GPPG +GP GP Sbjct: 874 GKPGPRGQRGPTG-PRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGP 923 Score = 291 bits (744), Expect = 3e-78 Identities = 176/376 (46%), Positives = 204/376 (54%), Gaps = 44/376 (11%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGR---PGDLGPVGYQGMKGEKGSRGEKG 311 A+G PGL+G G +G G G PGE+G AG G PG GP G G GEKG+ GEKG Sbjct: 1037 AQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG 1096 Query: 312 SRGPKGYKGEKGKRGI---------DGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKG 362 +GP G G +G G+ G DG KGE+G PG G KG G +G GPPG +G Sbjct: 1097 PQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQG 1156 Query: 363 DPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE---------PGPPGEKGEAGDEG 413 GA G+ G GEPG G+ G G G G G PG PGPPGEKGE GD G Sbjct: 1157 PVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVG 1216 Query: 414 NPGPDGAPGERG--GP-GERGPRGTPGT------RGPRGDPGEA---GPQGDQGREGPVG 461 GP G PG RG GP G GP+G PG+ G +G+PGEA GP G+ G GP G Sbjct: 1217 PMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKG 1276 Query: 462 VPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGE---RGEDGPAGN-G 517 G+ GEAGP G G G +GPPG +G +G PGP G PGDPG GE G+DG G+ G Sbjct: 1277 ERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKG 1336 Query: 518 TEGFPGFPGYP---GNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYR 574 +G PG PG P G G PG G +G PG G EG G+ G G +G G Sbjct: 1337 EDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE----AGAEGPPGKT 1392 Query: 575 GPEGPQGPPGHQGPPG 590 GP GPQGP G GP G Sbjct: 1393 GPVGPQGPAGKPGPEG 1408 Score = 289 bits (739), Expect = 1e-77 Identities = 162/348 (46%), Positives = 187/348 (53%), Gaps = 20/348 (5%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLG---PVGYQGMKGEKGSRGEKGSR 313 G PG +G PG GE+G PG G +G AG G G +G P G G GE G +GE G Sbjct: 1075 GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEP 1134 Query: 314 GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373 G KG KG+KG+ G G G++G +G PG+ G G PG G QG G KGD GA G G Sbjct: 1135 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPP 1194 Query: 374 GEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPR 433 G G G G PG G +GD G G PGPPG +G G G GP G PG G G G + Sbjct: 1195 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1254 Query: 434 GTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAP 493 G PG G G PGEAG G +G G G G PG AGP G KG GD+GP G+ G G P Sbjct: 1255 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFP 1314 Query: 494 GPAGPPGDP------GLMGERGEDGPAGN----GTEGFPGFPGYPGNRGAPGINGTKGYP 543 G GPPG+P G+ G++GEDG G G G G PG PG RG PG G +G Sbjct: 1315 GDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ 1374 Query: 544 GLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G KG +GEAG G P G G G +GP G GP G +G PGP Sbjct: 1375 GEKGAKGEAGAEG-------PPGKTGPVGPQGPAGKPGPEGLRGIPGP 1415 Score = 288 bits (737), Expect = 2e-77 Identities = 166/364 (45%), Positives = 195/364 (53%), Gaps = 31/364 (8%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP------VGYQGMKGEKGSRGE 309 RGP G RG G G GKPG G G G PG PG+ GP VG+ G KG G G+ Sbjct: 882 RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGK 941 Query: 310 KGSRGPKGYKGE---KGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366 G G G +GE +GK G G GV G G G G G G G GPPG +G PGA Sbjct: 942 DGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGA 1001 Query: 367 FGLKGEKGEPGADGEAGRPGSSGPSG---DEGQPGEPGPPGEKGEAGDEGNPGPDGAPGE 423 G +G KG+PG G +G+ G +G G + G PG G PG KG G +G PGP G+PGE Sbjct: 1002 AGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGE 1061 Query: 424 RGG---------PGERGPRGTPGTRGPRGDPGEAGPQGDQGR---EGPVGVPGDPGEAGP 471 RG PG GP+G PG G +G PGE GPQG GR +GPVG+PG G AG Sbjct: 1062 RGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1121 Query: 472 IGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNR 531 G G +G+ G PG +G++G G GPPG PGL G G G AG +G PG G G Sbjct: 1122 PGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG--DGEPGPRGQQGMF 1179 Query: 532 GAPGINGTKGYPGLKGDEGEAGDPG-----DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQ 586 G G G +G+PG G G G PG +N D+ P G G G RGP+GP G G Q Sbjct: 1180 GQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1239 Query: 587 GPPG 590 GPPG Sbjct: 1240 GPPG 1243 Score = 286 bits (732), Expect = 7e-77 Identities = 170/393 (43%), Positives = 194/393 (49%), Gaps = 63/393 (16%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RGPPG G G G G PG G KGE+GDPG G G G G G+ G RG G+ G Sbjct: 528 RGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGG 587 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375 +G GE G +G G DG+ PGLPG KG G G QGPPGP GD G G GE G Sbjct: 588 RGMPGEPGAKGDRGFDGL------PGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP 641 Query: 376 PGADGEAGRPGSSGPSGDEGQPGEP------GPPGEKGEAGDEGNPGP---DGAPGERGG 426 G GEAG G GP G G PG+P GPPG KG G +G PGP G PG +G Sbjct: 642 RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 701 Query: 427 PGERGPRGTPGTRGPRGDPGEA------GPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480 PG +GP G PG +GP+G PG A GP G G+EG G G G GP GP GY G Sbjct: 702 PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGP 761 Query: 481 EGPPGSEGARGAPGPAGPPGDPGL------------------MGERGEDGPAG------- 515 G G++G RG G G G+ G +G RGEDGP G Sbjct: 762 RGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP 821 Query: 516 ------------NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGE---AGDPG--DD 558 G G PG PGYPG +G G G G+PG G++G AG PG Sbjct: 822 TGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQ 881 Query: 559 NNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 PRG +GA+G G GP+G G GPPGP Sbjct: 882 RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGP 914 Score = 284 bits (727), Expect = 3e-76 Identities = 157/346 (45%), Positives = 187/346 (54%), Gaps = 21/346 (6%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314 A G GL+G G +GE G PG G+ G GD G G +GP G G +G KG G G G Sbjct: 767 ADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 826 Query: 315 PKGYKGEKGKRGIDGVDGV------KGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFG 368 P G GEKGK G+ G+ G KG G+PG PG G G G+ G PGP+G G G Sbjct: 827 PSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTG 886 Query: 369 LKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPG 428 +G +G A G G+PG G SG +G PG PPGE+G G + GP G PG +G PG Sbjct: 887 PRGSRG---ARGPTGKPGPKGTSGGDGPPG---PPGERGPQGPQ---GPVGFPGPKGPPG 937 Query: 429 ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEG 488 G G PG G RG+ G G G G G VG G GE GPIG +G+ G GPPG +G Sbjct: 938 PPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQG 997 Query: 489 ARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGD 548 GA G G GDPG G G+DGPA G GFPG G PG +GAPG+ G +G G G Sbjct: 998 LPGAAGKEGAKGDPGPQGISGKDGPA--GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGP 1055 Query: 549 EGEAGDPGDDNNDIAPRGVKGAKGYRGPEGP---QGPPGHQGPPGP 591 G G+ G P G+ G G +GP GP +G PG +GP GP Sbjct: 1056 VGSPGERGSAGT-AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGP 1100 Score = 284 bits (726), Expect = 3e-76 Identities = 157/342 (45%), Positives = 188/342 (54%), Gaps = 13/342 (3%) Query: 257 GPPGLRGDPGFEGERGKPGLPG------EKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310 G PG G G +G+ G PGLPG KG G PG PG G G +G+ G+ G RG++ Sbjct: 823 GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 882 Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370 G GP+G +G +G G G G G G PG PG +G G G G PGPKG PG G Sbjct: 883 GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 942 Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGER 430 G G PG GE G G +GP G G G GP GE G G+ G+PGP G PGE+G PG Sbjct: 943 GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 1002 Query: 431 GPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGAR 490 G G G GP+G G+ GP G +G G G+PG G G G +G +G GP GS G R Sbjct: 1003 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1062 Query: 491 GAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEG 550 G+ G AGP G PG G +G GPAG G PG G +G G +G +G GL G G Sbjct: 1063 GSAGTAGPIGLPGRPGPQGPPGPAGE-----KGAPGEKGPQGPAGRDGVQGPVGLPGPAG 1117 Query: 551 EAGDPGDDNN--DIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 AG PG+D + +I G KG+KG +G GP GPPG QGP G Sbjct: 1118 PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG 1159 Score = 284 bits (726), Expect = 3e-76 Identities = 164/365 (44%), Positives = 189/365 (51%), Gaps = 41/365 (11%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGD------PGRPGDLGPVGYQGMKGEKGSRGEK 310 G G G PG G +G PG PGEKGE GD PG PG GP G G G +G G Sbjct: 1186 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV 1245 Query: 311 GSRGPKGYKGEKGKRG---------IDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361 GS G G KGE G+ G + G G +GE G G PG G PG G G GPK Sbjct: 1246 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK 1305 Query: 362 GDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP---GPD 418 G+PG G G+ G PG G AG+ G G G++G PG+PGPPG GEAG G P GP Sbjct: 1306 GNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPP 1365 Query: 419 GAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYR 478 GA G G GE+G +G G GP G G GPQG G+ GP G+ G PG Sbjct: 1366 GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV--------- 1416 Query: 479 GDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGIN 537 G++G PG+ G G PGP GPPG PGL G+ G G G+ G G G PG G +G G+ Sbjct: 1417 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1476 Query: 538 GTKGYPGLKGD------EGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQ------GPPGH 585 GT+G PG KGD G G PG P+G KG KG GP G + GPPG Sbjct: 1477 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLP-GPQGPKGNKGSTGPAGQKGDSGLPGPPGS 1535 Query: 586 QGPPG 590 GPPG Sbjct: 1536 PGPPG 1540 Score = 282 bits (722), Expect = 1e-75 Identities = 168/378 (44%), Positives = 193/378 (51%), Gaps = 44/378 (11%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G G G PG GE+G PG G++G GDPG G G G G++G G RG G++G Sbjct: 982 GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1041 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376 G KG +G +G G G GE G G G G PG G QGPPGP G+ GA G KG +G Sbjct: 1042 GLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPA 1101 Query: 377 GAD---------GEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPD------GAP 421 G D G AG GS G GD+G+ GEPG G KG+ G+ G PGP GAP Sbjct: 1102 GRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAP 1161 Query: 422 GERGGPGERGPRGTPGTRGPRGD------------------PGEAGPQGDQGREGPVGVP 463 G GG GE GPRG G G +GD PG G +G+ G GP+G P Sbjct: 1162 GIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1221 Query: 464 GDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGD---PGLMGERGEDGPAG----N 516 G PG GP GP G G +GPPGS G+ G G G PG+ PG GE G GP G Sbjct: 1222 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1281 Query: 517 GTEGFPGFPGYPGNRGAPGINGTKGYP---GLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573 G G PG G PG +G PG +G KG P G GD G G+PG D G KG G Sbjct: 1282 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQD-GVGGDKGEDGD 1340 Query: 574 RGPEGPQGPPGHQGPPGP 591 G GP GP G GPPGP Sbjct: 1341 PGQPGPPGPSGEAGPPGP 1358 Score = 281 bits (720), Expect = 2e-75 Identities = 165/374 (44%), Positives = 196/374 (52%), Gaps = 41/374 (10%) Query: 257 GPPGLRGDPG---FEGERGKPGLPGEKGEAGDPGR---PGDLGPVGYQGMKGEKGSRGEK 310 GPPG +G+PG G +G G PGEKG G PG PG GP G+ G +G+ G +G Sbjct: 688 GPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL 747 Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370 G GP+G G G RG+ G DGV+G G G G G PGF G G G +G+ G G + Sbjct: 748 GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 807 Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQ------PGEPGPPGEKGEAGDEGNPGPDGAPGER 424 GE G G G AG G GPSG G+ PG PG PG +G G G PG GA GE+ Sbjct: 808 GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 867 Query: 425 G--------GP-GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475 G GP G+RGP G G+RG RG G+ GP+G G +GP G PG+ G GP GP Sbjct: 868 GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPV 927 Query: 476 GYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-------------NGTEGFP 522 G+ G +GPPG G G PG G G+ G G+ G GP G G G P Sbjct: 928 GFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHP 987 Query: 523 GFPGYPGNRGAPGI---NGTKGYP---GLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGP 576 G PG PG +G PG G KG P G+ G +G AG G P G +GA G +G Sbjct: 988 GPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLP-GAQGAPGLKGG 1046 Query: 577 EGPQGPPGHQGPPG 590 EGPQGPPG G PG Sbjct: 1047 EGPQGPPGPVGSPG 1060 Score = 278 bits (710), Expect = 2e-74 Identities = 159/350 (45%), Positives = 190/350 (54%), Gaps = 23/350 (6%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G PGL GD G GERG G PG G+ G G G++GP +G+ GE G RG G RG Sbjct: 604 GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP---RGLPGEAGPRGLLGPRGTP 660 Query: 317 GYKGEKGKRGIDGVDGVKGEMG---YPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373 G G+ G G+DG G KG MG PG PG +G+PG G+ GP GP G PG G +G+ Sbjct: 661 GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP 720 Query: 374 GE---PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGER 430 G PGADG G PG G SG++G G PGP G G G G G DG G +G GE+ Sbjct: 721 GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK 780 Query: 431 GPRGTPG------TRGPRGDPGEAGPQGDQGREGP---VGVPGDPGEAGPIGPKGYRGDE 481 G G PG +G RG+ G+ GP+G+ G EGP G GDPG +G G KG G Sbjct: 781 GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP 840 Query: 482 GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTK 540 G PG G +G G G PG PG GE+G G AG G G G G G+RGA G G Sbjct: 841 GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKP 900 Query: 541 GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G G G +G G PG+ P+G +G G+ GP+GP GPPG G PG Sbjct: 901 GPKGTSGGDGPPGPPGER----GPQGPQGPVGFPGPKGPPGPPGKDGLPG 946 Score = 277 bits (709), Expect = 3e-74 Identities = 157/344 (45%), Positives = 182/344 (52%), Gaps = 21/344 (6%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RGP G +G GF G +G PG PG+ G PG PG G G+QG G G G G +GP Sbjct: 918 RGPQGPQGPVGFPGPKGPPGPPGKDGL---PGHPGQRGETGFQGKTGPPGPGGVVGPQGP 974 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375 G G G+RG G G GE G PG G +G+ G G QG G G G G GE+G Sbjct: 975 TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL 1034 Query: 376 PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD---EGNPGPDGAPG---ERGGPGE 429 PGA G G G GP G G G PG G G AG G PGP G PG E+G PGE Sbjct: 1035 PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1094 Query: 430 RGPRGTPG---TRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGS 486 +GP+G G +GP G PG AGP G G +G G G+PG+ G G KG G GPPG Sbjct: 1095 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1154 Query: 487 EGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLK 546 +G GAPG AG G+PG G++G G G+ EG GFPG PG G G+ G G G Sbjct: 1155 QGPVGAPGIAGGDGEPGPRGQQGMFGQKGD--EGARGFPGPPGPIGLQGLPGPPGEKGEN 1212 Query: 547 GDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 GD G G PG P G +G +G G +GPQGPPG G G Sbjct: 1213 GDVGPMGPPG-------PPGPRGPQGPNGADGPQGPPGSVGSVG 1249 Score = 276 bits (705), Expect = 9e-74 Identities = 161/369 (43%), Positives = 187/369 (50%), Gaps = 36/369 (9%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RG PG +G PG +G G G PG G G+ G G GP+G + G G +G G G Sbjct: 1032 RGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIG---LPGRPGPQGPPGPAGE 1088 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGP---PGPKGDPGAFGLKGE 372 KG GEKG +G G DGV+G +G PG G GSPG DG +G PG KG G G G Sbjct: 1089 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP 1148 Query: 373 KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGP 432 G PG G G PG +G G+ G G+ G G+KG+ G G PGP G G +G PG G Sbjct: 1149 PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1208 Query: 433 RGTPGTRGPRGDPGEAGPQGDQ---GREGPVGVP------------GDPGEAGPIGPKGY 477 +G G GP G PG GP+G Q G +GP G P G+PGEAG GP G Sbjct: 1209 KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1268 Query: 478 RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGI 536 G GP G G +G GP G G PG G G+DGP GN G GFPG PG PG G G Sbjct: 1269 AGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQ 1328 Query: 537 NGT---------KGYPGLKGDEGEAGDPGDDNNDIAP-----RGVKGAKGYRGPEGPQGP 582 +G G PG G GEAG PG P G +G KG +G G +GP Sbjct: 1329 DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP 1388 Query: 583 PGHQGPPGP 591 PG GP GP Sbjct: 1389 PGKTGPVGP 1397 Score = 275 bits (704), Expect = 1e-73 Identities = 156/351 (44%), Positives = 182/351 (51%), Gaps = 30/351 (8%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RG PG G PG G G PG G G G+PG PG G G QG+ G +G G G +GP Sbjct: 657 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 716 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGL------ 369 +G G G G DG G G+ G G G G PG G G PGP+G GA G+ Sbjct: 717 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 776 Query: 370 KGEKGE---PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGG 426 KGEKGE PG G+ G G G G G GE GP G KG AG G+PGP G GE+G Sbjct: 777 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 836 Query: 427 PGERGPRGTPGTRGPRGD---PGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGP 483 G G G PG +GP+G PG G G++G G G PG G+ GP GP+G RG GP Sbjct: 837 LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 896 Query: 484 PGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYP 543 G G +G G GPPG PG G +G GP GFPG G G PG +G G+P Sbjct: 897 TGKPGPKGTSGGDGPPGPPGERGPQGPQGPV--------GFPGPKGPPGPPGKDGLPGHP 948 Query: 544 GLKGD---EGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G +G+ +G+ G PG P GV G +G G GP G GH GPPGP Sbjct: 949 GQRGETGFQGKTGPPG-------PGGVVGPQGPTGETGPIGERGHPGPPGP 992 Score = 266 bits (681), Expect = 6e-71 Identities = 165/398 (41%), Positives = 193/398 (48%), Gaps = 59/398 (14%) Query: 253 QPARGPPGL--RGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310 +PA PG+ G PG G G G PG +G G PG PGD GP G G+ G G G Sbjct: 430 EPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPP 489 Query: 311 GSR-------GPKGYKGE--------------------KGKRGIDGVDGVKGEMGYPGLP 343 G+ G G KG +G G G+ G G +G PG Sbjct: 490 GTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSS 549 Query: 344 GCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPP 403 G KG G G QGP G +G PG G G++G PGADG G PG G GD G G PG P Sbjct: 550 GAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLP 609 Query: 404 GEKGEAGDEGNPGPDGAPGE---RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPV 460 G+KG G+ G GP G PG+ RG GE GPRG PG GPRG G G G G+ G Sbjct: 610 GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 669 Query: 461 GVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTE 519 GV G PG G +GP+G G G G+ G +G PGP GP G PG G +G+ G AG G + Sbjct: 670 GVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 729 Query: 520 GFPGFP---------------------GYPGNRGAPGINGTKGYPGLKGDEGEAGDPG-- 556 G PG P GYPG RG G +G +G G KG++GE G PG Sbjct: 730 GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 789 Query: 557 DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGP---PGP 591 D RG G G RG +GP+GP G GP PGP Sbjct: 790 GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 827 Score = 246 bits (629), Expect = 6e-65 Identities = 139/295 (47%), Positives = 167/295 (56%), Gaps = 14/295 (4%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGE---KGSRGEKGS 312 +G PG G+PG GE G G GE+GE G+ G PG GP G +G G+ KG+ G G Sbjct: 1254 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1313 Query: 313 RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372 G G GE G G DGV G KGE G PG PG G G G GPPG +G PGA G +G Sbjct: 1314 PGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGR 1373 Query: 373 KGEPGADGEAGR---PGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGE 429 +GE GA GEAG PG +GP G +G G+PGP G +G G G G GA G+ G PG Sbjct: 1374 QGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGP 1433 Query: 430 RGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGA 489 GP G PG +G DPG +G++G G +G+ G PGE G G +G G +G PG++G Sbjct: 1434 MGPPGLPGLKG---DPGS---KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGD 1487 Query: 490 RGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPG 544 G PGPAGP G PG G G GP GN +G G G G+ G PG G+ G PG Sbjct: 1488 GGIPGPAGPLGPPGPPGLPGPQGPKGN--KGSTGPAGQKGDSGLPGPPGSPGPPG 1540 Score = 225 bits (573), Expect = 2e-58 Identities = 118/255 (46%), Positives = 138/255 (54%), Gaps = 9/255 (3%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGE----- 309 A GPPG +G PG +G +G PG G G+ G PG PG G G G KGE G G+ Sbjct: 1289 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1348 Query: 310 -KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFG 368 G GP G G++G G G +G +GE G G G +G PG G GP GP G PG G Sbjct: 1349 PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEG 1408 Query: 369 LKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPG 428 L+G G G G G G GP G G PG PG G+ G G++G+PG G G G G Sbjct: 1409 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG 1468 Query: 429 ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEG 488 E+G RG PGT +G PG G G G GP+G PG PG GP GPKG +G GP G +G Sbjct: 1469 EKGDRGLPGT---QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG 1525 Query: 489 ARGAPGPAGPPGDPG 503 G PGP G PG PG Sbjct: 1526 DSGLPGPPGSPGPPG 1540 Score = 213 bits (541), Expect = 1e-54 Identities = 151/380 (39%), Positives = 175/380 (46%), Gaps = 70/380 (18%) Query: 273 KPGLPGEKGEAGDPGRPGDLG----PVGYQGMKGEKGSRGE----------KGSRGPKGY 318 KP P E PG P + + G GEKG +GE +G GP G Sbjct: 392 KPTSP--PNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGP 449 Query: 319 KGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD-PGAFGLKGEKGEPG 377 G G G+ G G G+ G G PG G PG DG+ GPPG P +G G KG Sbjct: 450 AGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTI 509 Query: 378 ADGEA--------------GRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGE 423 + EA G PG G +G G G PG G KGE+GD G GP G G Sbjct: 510 SAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGP 569 Query: 424 RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGP 483 G G+ G RG PG G RG PGE G +GD+G +G G+PGD G +G RG +GP Sbjct: 570 PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGH------RGERGPQGP 623 Query: 484 PGSE------------GARGAPGPAGP------------PGDPGLMGERGEDGPAGN-GT 518 PG G RG PG AGP PG PG+ G G GP GN G Sbjct: 624 PGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGP 683 Query: 519 EGFPGFPGY---PGNRGAPGINGTKGYPGLKGDEGE---AGDPGDDNNDIAP--RGVKGA 570 +G PG PG PG +G PG G G PG KG +G+ AG PG D P G G Sbjct: 684 QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGE 743 Query: 571 KGYRGPEGPQGPPGHQGPPG 590 KG GP GPQGP G+ GP G Sbjct: 744 KGALGPPGPQGPIGYPGPRG 763 Score = 194 bits (493), Expect = 4e-49 Identities = 107/224 (47%), Positives = 126/224 (56%), Gaps = 21/224 (9%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP---VGYQGMKGEKGSRGEKGSR 313 G G+ GD G +G+ G+PG PG GEAG PG PG GP G +G +GEKG++GE G+ Sbjct: 1327 GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAE 1386 Query: 314 GPKGY------KGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAF 367 GP G +G GK G +G+ G+ G +G GLPG G DG GP GP G PG Sbjct: 1387 GPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ---DGPPGPMGPPGLPGLK 1443 Query: 368 ---GLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGER 424 G KGEKG PG G G PG G GD G PG G PG KG+ G G GP G PG Sbjct: 1444 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP 1503 Query: 425 GGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGE 468 G PG +GP+G G+ GP AG +GD G GP G PG PGE Sbjct: 1504 GLPGPQGPKGNKGSTGP------AGQKGDSGLPGPPGSPGPPGE 1541 Score = 157 bits (398), Expect = 4e-38 Identities = 99/238 (41%), Positives = 114/238 (47%), Gaps = 31/238 (13%) Query: 365 GAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE--PGPPGEKGEAGDEGNPGPDGAPG 422 GA+G KG+KGEP +PG GPPG G AG G PG G G Sbjct: 420 GAYGEKGQKGEPAVV----------------EPGMLVEGPPGPAGPAGIMGPPGLQGPTG 463 Query: 423 ERGGPGERGPRGTPGTRGPRGDPGEAGPQ-------GDQGREGPVGVPGDPGEAGPIGPK 475 G PG+RGP G PG G G PG G G G +GP + +A I + Sbjct: 464 PPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPT-ISAQEAQAQAILQQ 522 Query: 476 GYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAP 534 GPPG G G PGP G PG G GE G+ GP G G +G PG G PG RG P Sbjct: 523 ARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRP 582 Query: 535 GINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592 G +G +G PG + G GD G D P G KG +G RGP+GP GPPG G G D Sbjct: 583 GADGGRGMPG---EPGAKGDRGFDGLPGLP-GDKGHRGERGPQGPPGPPGDDGMRGED 636 Score = 103 bits (258), Expect = 6e-22 Identities = 61/141 (43%), Positives = 73/141 (51%), Gaps = 24/141 (17%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GPPG G PG G +G PG KGE G PG G +GP G QG KG++G G +GS Sbjct: 1429 GPPGPMGPPGLPGLKGDPG---SKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGS---- 1481 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376 G KG+ G PG G G PG G+ GP GPKG+ G+ G G+KG+ Sbjct: 1482 --------------PGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDS 1527 Query: 377 GADGEAGRPGSSGPSGDEGQP 397 G G PGS GP G+ QP Sbjct: 1528 GLPGP---PGSPGPPGEVIQP 1545 >gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] Length = 1860 Score = 301 bits (770), Expect = 3e-81 Identities = 164/344 (47%), Positives = 195/344 (56%), Gaps = 29/344 (8%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G PGL G PG +G G+PGL G KGE GDPGRPG PVG QG G G GE G G K Sbjct: 955 GAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPG---PVGEQGFMGFIGLVGEPGIVGEK 1011 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376 G ++G G GV G KG MG+PG+PG G+PG G QGPPG +G PG G KG +G Sbjct: 1012 G---DRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPR 1068 Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGN---------PGPDGAPGERGGP 427 G DG AG GS G G G G PG PG++G AG+ G+ PGP G PG +G P Sbjct: 1069 GPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLP 1128 Query: 428 GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487 GE GP+ G +GP G PGE GP+G G G G+PG+ G G +GP G G++G G Sbjct: 1129 GEPGPQ---GPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQR 1185 Query: 488 GARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGTKGYPGLK 546 G G G +GP G GL G+RG+ GP G +G +G G G G G PG+ G +G G Sbjct: 1186 GEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKS 1245 Query: 547 GDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G +GE G G KGAKGY+G G G PG GPPG Sbjct: 1246 GKQGEKG----------RTGAKGAKGYQGQLGEMGVPGDPGPPG 1279 Score = 288 bits (738), Expect = 1e-77 Identities = 177/399 (44%), Positives = 203/399 (50%), Gaps = 66/399 (16%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKG------------EK 304 GPPG+ G G G G PG G GE G G PG GP G +G KG E+ Sbjct: 1018 GPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQ 1077 Query: 305 GSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDP 364 GSRG KG GP+G G G++G+ G G G G+PG+PG G PG G+ G PGP+G Sbjct: 1078 GSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQ 1137 Query: 365 GAFGLKGE---KGEPGADGEAGRPGSSGPSGD------------EGQPGEP------GPP 403 G G GE KG PGA GE G PG +G GD GQ GEP GP Sbjct: 1138 GPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPM 1197 Query: 404 GEKGEAGDEGNPGPDGAPGERGGP---GERGPRGTPGTRGPRGDPGEAGPQGDQGRE--- 457 G G GD G+PGPDG GE+G GE GP G PG G RG G++G QG++GR Sbjct: 1198 GPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAK 1257 Query: 458 ---------GPVGVPGDPGEAGPIGPKGYRGDEGP---PGSEGARGAP------------ 493 G +GVPGDPG G GPKG RG GP PG GA+G P Sbjct: 1258 GAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIV 1317 Query: 494 GPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAG 553 GP GPPG G GE+GEDG A G G PG G G+RG G G GYPG +G +G G Sbjct: 1318 GPLGPPGPKGEKGEQGEDGKA-EGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRG 1376 Query: 554 DPGDDN--NDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 PG PRG G KG +G EGP+G G G PG Sbjct: 1377 KPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPG 1415 Score = 287 bits (735), Expect = 3e-77 Identities = 160/375 (42%), Positives = 196/375 (52%), Gaps = 39/375 (10%) Query: 256 RGPPGLRGDPGFEGERGK---PGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312 +G PG+ GDPGF+G++G PG PG +G+ G G+ GD G +G+ G G +G G+ G Sbjct: 858 QGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGP 917 Query: 313 RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372 G G +G KGK G G+ G +G++G G G G PG G++G PG KG PG GL G Sbjct: 918 PGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGV 977 Query: 373 KGEPGADGE---------------AGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEG---- 413 KGEPG G G PG G GD G G PG PG KG G G Sbjct: 978 KGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGG 1037 Query: 414 -----NPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGE 468 PGP G PG RG PG RG +G G RGP G GE G +G +G GP G PG PG+ Sbjct: 1038 MGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQ 1097 Query: 469 AGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGF 524 G G +G+ G G PG G G PG G PG+PG G +G GP G G G G Sbjct: 1098 QGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGE 1157 Query: 525 PGYPGNRGAPGINGTKGYPGLKGDEGEAGDPG--DDNNDIAPRGVKGAKGYRGPEGPQGP 582 PG PG G G G G PG +G G+ G+PG D+ + P G+KG +G GP+G G Sbjct: 1158 PGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGE 1217 Query: 583 PGHQ------GPPGP 591 G + GPPGP Sbjct: 1218 KGQEGLMGEDGPPGP 1232 Score = 284 bits (727), Expect = 3e-76 Identities = 167/385 (43%), Positives = 195/385 (50%), Gaps = 49/385 (12%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 +G G+ G PG G +G G PG G G PG PG GP G +G G +G++G +G RGP Sbjct: 1011 KGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGP 1070 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGF---DGIQGPPGPKGDPGAFGLKGE 372 G GE+G RG+ G G +G G PG G G G G G PGP G PG GL GE Sbjct: 1071 DGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGE 1130 Query: 373 KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGE---KGEAGDEGNPGPDGAPGERGGP-- 427 G G G G PG GP G G GEPG PGE KG+ G G PG G G+RG P Sbjct: 1131 PGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGL 1190 Query: 428 -GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPV---GVPGDPGEAGPIGPKGYRGDEGP 483 G+ GP G G +G RGDPG G G++G+EG + G PG PG G GP+G G +G Sbjct: 1191 EGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGE 1250 Query: 484 PGSEGARGA------------PGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFPGY 527 G GA+GA PG GPPG PG G RG GP G G +G PG GY Sbjct: 1251 KGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGY 1310 Query: 528 PGNR------GAPGINGTKGY----------PGLKGDEGEAGDPGD--DNNDIAPRGVKG 569 G++ G PG G KG PG GD G GD GD + D G +G Sbjct: 1311 DGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEG 1370 Query: 570 AKGYRGPEGPQGPPGHQGP---PGP 591 +G RG G QG PGH GP PGP Sbjct: 1371 VQGLRGKPGQQGQPGHPGPRGWPGP 1395 Score = 283 bits (723), Expect = 8e-76 Identities = 168/392 (42%), Positives = 203/392 (51%), Gaps = 57/392 (14%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDP---------------GRPGDL---GPVGYQ 298 G PGL G PG +GERG PG+PG++G+ G P G PG+L GP G Sbjct: 760 GLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVP 819 Query: 299 GMKGEKGSRGEKGSRGPKGYK---------GEKGKRGIDGVDGVKGEMGYPGLPGCKGSP 349 G+ G+ G G G GPKG K G KG +G GV GV G+ G+ G G +G P Sbjct: 820 GLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLP 879 Query: 350 GFDGIQGPPGP---KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE---PGPP 403 GF G +G PGP GD G+ G G G G G+ G PG +GP G +G+PG PGP Sbjct: 880 GFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPR 939 Query: 404 GEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP---GTRGPRGDPGEAGPQGDQGREGPV 460 G+ G GDEG GP GAPG G PG +G G P G +G GDPG GP G+QG G + Sbjct: 940 GQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFI 999 Query: 461 GVPGDP------------GEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGD---PGLM 505 G+ G+P G G GPKG G G PG G G PGP GPPG PG+ Sbjct: 1000 GLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMR 1059 Query: 506 GERGEDGPAG----NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNND 561 G +G GP G G +G G G PG +G PG G +G G +G G G PG Sbjct: 1060 GAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPS 1119 Query: 562 IAP--RGVKGAKGYRGPEGPQGPPGHQGPPGP 591 P +G+ G G +GP+GP GPPG GP GP Sbjct: 1120 GPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGP 1151 Score = 280 bits (717), Expect = 4e-75 Identities = 170/389 (43%), Positives = 199/389 (51%), Gaps = 57/389 (14%) Query: 257 GPPGLRGDPGFEG------ERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310 GPPG +G G+ G E+G+PG G G G PGR G GPV G G KGSRG Sbjct: 703 GPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPV---GDPGPKGSRGYI 759 Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGC---KGSPGFDGIQGP---PGPKGDP 364 G G G G G+RG+ GV G +G+MG PG PG +G PG DG G PGP G P Sbjct: 760 GLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVP 819 Query: 365 ---------GAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP 415 G G G KG G G G PG G G++G PG G PG +G+ G +G P Sbjct: 820 GLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLP 879 Query: 416 GPDGA---PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGD---PGEA 469 G GA PG G G++G G PG GP G PG+ GP GD G EG G PG PG Sbjct: 880 GFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPR 939 Query: 470 GPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN----GTEGFPGF- 524 G +GP+G G GPPG+ G G PG G PG PGL G +GE G G G +GF GF Sbjct: 940 GQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFI 999 Query: 525 -----PGYPGNR---------GAPGINGTKGYPGLKGDEGEAGDPGDDN--NDIAPRGVK 568 PG G + G PG G+ G+PG+ G G G+PG P G++ Sbjct: 1000 GLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMR 1059 Query: 569 GAKGYRGPEGPQGPPGHQ------GPPGP 591 GAKG RGP GP GP G Q GPPGP Sbjct: 1060 GAKGRRGPRGPDGPAGEQGSRGLKGPPGP 1088 Score = 280 bits (717), Expect = 4e-75 Identities = 166/379 (43%), Positives = 198/379 (52%), Gaps = 43/379 (11%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RGP G G G +G G G G +G+ G+ G PGD GP G G KG +GS G G+ G Sbjct: 1239 RGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGR 1298 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDG-IQGPPGPKGDPGAFGLKGEKG 374 G +GE G G DG G+ G +G PG G KG G DG +GPPGP GD G G +G++G Sbjct: 1299 MGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRG 1358 Query: 375 EPGADGEAGRPGSSG---PSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERG 431 EPG G G+ G G G +GQPG PGP G G G +G GP G G+ G PG RG Sbjct: 1359 EPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRG 1418 Query: 432 PRGTPGTRGPRGDPGE------AGPQGDQGREGPVGVPG---DPGEAGPIGPKGYRGD-- 480 +G G GPRG G AGP G GR+G G G D G+ GP+GP G RG+ Sbjct: 1419 VQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPG 1478 Query: 481 -------EGPPGSEGARGAPGPAGPPGD---------PGLMGERGEDG-PAGNGTEGFPG 523 +GPPG +G G PG GPPG PG GE G G P +G GFPG Sbjct: 1479 VAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPG 1538 Query: 524 FPGYPGNRGAPG------INGTKGYPGLKGDEGEAGDPG--DDNNDIAPRGVKGAKG--- 572 G G +G PG I G +G PGL G EG G G + P+G KG++G Sbjct: 1539 MAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWG 1598 Query: 573 YRGPEGPQGPPGHQGPPGP 591 +GP GP GP G GPPGP Sbjct: 1599 LQGPRGPPGPRGRPGPPGP 1617 Score = 276 bits (707), Expect = 5e-74 Identities = 158/364 (43%), Positives = 198/364 (54%), Gaps = 29/364 (7%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 +GPPG +G PG G++G G G G G PG PG GP G +G+ GE G +G +G GP Sbjct: 1083 KGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGP 1142 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGI---QGPPGPKGDPGAFG---L 369 G G KG G G G+ GE G G G G+PG G+ +G PG +GD G G L Sbjct: 1143 PGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGL 1202 Query: 370 KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPG------PPGEKGEAGDEGNPGPDGAPG- 422 KG++G+PG DGE G G G G++G PG PG P G+ G+ G++G G GA G Sbjct: 1203 KGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGY 1262 Query: 423 -----ERGGPGERGPRGTPGTRGPRGD---PGEAGPQGDQGREGPVGVPGDPGEAGPIGP 474 E G PG+ GP GTPG +G RG G G G QG G G G G GP+GP Sbjct: 1263 QGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGP 1322 Query: 475 KGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN----GTEGFPGFPGYPGN 530 G +G++G G +G A GP GPPGD G +G+RG+ G G+ G EG G G PG Sbjct: 1323 PGPKGEKGEQGEDGK--AEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQ 1380 Query: 531 RGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAP--RGVKGAKGYRGPEGPQGPPGHQGP 588 +G PG G +G+PG KG +G G G AP RGV+G +G GP G G G +G Sbjct: 1381 QGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGI 1440 Query: 589 PGPD 592 GPD Sbjct: 1441 AGPD 1444 Score = 274 bits (701), Expect = 3e-73 Identities = 181/433 (41%), Positives = 199/433 (45%), Gaps = 99/433 (22%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGD---------LGPVGYQGMKGEKGS 306 RG G+ G PG GERG PGL G GE G PG PG LGP+GY G KG KG Sbjct: 783 RGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGL 842 Query: 307 RGEKGSRGPKGYKGEKGKRGIDG---VDGVKGEMGYPGLPGCKGSPG---------FDGI 354 G G G KG KGE+G G+ G G KG G PG PG +G PG G Sbjct: 843 MGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGF 902 Query: 355 QGPPGPKGDPGAFGLKGE------KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPG---- 404 GPPGP+G PG G G+ KG+PGA G G G GP GDEG G PG PG Sbjct: 903 PGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQ 962 Query: 405 --------------EKGEAGDEGNPGPDGA------------PGERGGPGERGPRGTPGT 438 KGE GD G PGP G PG G G+RG G PG Sbjct: 963 PGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGV 1022 Query: 439 RGPRGD------------PGEAGPQGDQGREGPVGVPGDPGEAGPIGP------KGYRGD 480 GP+G PGE GPQG G GP G+ G G GP GP +G RG Sbjct: 1023 PGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGL 1082 Query: 481 EGPP---------------------GSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTE 519 +GPP GS G G PGP+GPPG GL GE G GP G Sbjct: 1083 KGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGP--QGPI 1140 Query: 520 GFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGP 579 G PG G G GA G G G G+KGD G G PG+ I RG G +G GP GP Sbjct: 1141 GPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGL-IGQRGEPGLEGDSGPMGP 1199 Query: 580 QGPPGHQGPPGPD 592 G G +G PGPD Sbjct: 1200 DGLKGDRGDPGPD 1212 Score = 273 bits (697), Expect = 8e-73 Identities = 158/363 (43%), Positives = 185/363 (50%), Gaps = 28/363 (7%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGY---QGMKGEKGSRGEKGS 312 +GP G G PG G +G PG GE G G+ G GDLGP+G QG+ G++G G +G Sbjct: 1134 QGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGD 1193 Query: 313 RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372 GP G G KG RG G DG GE G GL G G PG G+ G GP+G G G KG Sbjct: 1194 SGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGR 1253 Query: 373 KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGP 432 G GA G G+ G G GD G PG PGP G +G G G PG GA GE G G G Sbjct: 1254 TGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGH 1313 Query: 433 RGTPGTRGPRGDPGEAGPQGDQGR-EGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGA-- 489 +G G GP G GE G QG+ G+ EGP G PGD G G G +G GD G PG EG Sbjct: 1314 KGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQG 1373 Query: 490 -------RGAPGPAGPPGDPGLMGERGEDGPAG-------------NGTEGFPGFPGYPG 529 +G PG GP G PG G +G +GP G G +G PG G G Sbjct: 1374 LRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVG 1433 Query: 530 NRGAPGINGTKGYPGLKGDEGEAGDPGDDNN--DIAPRGVKGAKGYRGPEGPQGPPGHQG 587 +G GI G G PG G G+ G+ GDD + + P G +G G G G QGPPG +G Sbjct: 1434 RQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKG 1493 Query: 588 PPG 590 G Sbjct: 1494 ESG 1496 Score = 270 bits (689), Expect = 7e-72 Identities = 173/421 (41%), Positives = 194/421 (46%), Gaps = 87/421 (20%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVG---------YQGMKGEKGSR 307 GPPGL G PG G RG G PG G G PG PG G G + G KG+ G Sbjct: 637 GPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLP 696 Query: 308 GEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGP---PGPKGDP 364 G G+ GP G KG KG G G G +G+ G G PG KG PG G+ GP PGPKG Sbjct: 697 GLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSR 756 Query: 365 GAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPG------PPGEKGEAGDEGNPGPD 418 G GL G G PG+DGE G PG G G G PG PG PPG G G+ G PGP Sbjct: 757 GYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPP 816 Query: 419 GAPGERGGPGERGPRGTPGTRGPRG---DPGEAGPQGDQGREGPVGVPGDPG-------- 467 G PG G G GP G PG +G +G GE G +GD+G +G GV GDPG Sbjct: 817 GVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQ 876 Query: 468 ----------EAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-- 515 + GP+G G +G G PG G G PG GPPGD G G +G+ G G Sbjct: 877 GLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLP 936 Query: 516 --------NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPG----------- 556 G EG G PG PG G PG G G PGL G +GE GDPG Sbjct: 937 GPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFM 996 Query: 557 ---------------DDNNDIAPRGVKGAKGYR------------GPEGPQGPPGHQGPP 589 D + P GV G KG G GPQGPPG +GPP Sbjct: 997 GFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPP 1056 Query: 590 G 590 G Sbjct: 1057 G 1057 Score = 266 bits (680), Expect = 7e-71 Identities = 159/379 (41%), Positives = 198/379 (52%), Gaps = 52/379 (13%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312 Q +G G +G G++G+ G+ G+PG+ G G P G KG +GS G G+ Sbjct: 1248 QGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTP------------GPKGSRGSLGPTGA 1295 Query: 313 RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDG-IQGPPGPKGDPGAFGLKG 371 G G +GE G G DG G+ G +G PG G KG G DG +GPPGP GD G G +G Sbjct: 1296 PGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRG 1355 Query: 372 EKGEPGADGEAGRPGSS---GPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPG 428 ++GEPG G G+ G G G +GQPG PGP G G G +G GP G G+ G PG Sbjct: 1356 DRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPG 1415 Query: 429 ERGPRGTPGTRGPRGDPGE------AGPQGDQGREGPV---GVPGDPGEAGPIGPKGYRG 479 RG +G G GPRG G AGP G GR+G G GD G+ GP+GP G RG Sbjct: 1416 RRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRG 1475 Query: 480 D---------EGPPGSEGARGAPGPAGPPGD------PGLMGERGEDG----PAGNGTEG 520 + +GPPG +G G PG GPPG GL G +GE G P +G G Sbjct: 1476 NPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMG 1535 Query: 521 FPGFPGY------PGNRGAPGINGTKGYPGLKGDEGEAGDPG--DDNNDIAPRGVKGAKG 572 FPG G PG+ G GI G +G PGL G EG G G + P+G KG++G Sbjct: 1536 FPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRG 1595 Query: 573 YRGPEGPQGPPGHQGPPGP 591 G +GP+GPPG +G PGP Sbjct: 1596 DWGLQGPRGPPGPRGRPGP 1614 Score = 259 bits (661), Expect = 1e-68 Identities = 151/341 (44%), Positives = 176/341 (51%), Gaps = 18/341 (5%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GPPG +GD G G G PGLPG G G G PG G G G G KG +G+ G K Sbjct: 625 GPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGK 684 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376 + DG KG+MG PGL G G PG G +G PGP G PG G G +G P Sbjct: 685 AH------------DGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSP 732 Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436 GA G GR G GP GD G G G G G G G+ G G PG G G+ G G P Sbjct: 733 GAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFP 792 Query: 437 GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPA 496 G G RG PG G G+ G GP GVPG G+ G +GP GY G +G G G+ G PG Sbjct: 793 GVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLK 852 Query: 497 GPPGDPGLMGERGEDGPAGN-GTEGFPGFP---GYPGNRGAPGINGTKGYPGLKGDEGEA 552 G G+ G+ G G+ G G+ G++G PGFP G PG G G G+ G+PG G EG Sbjct: 853 GDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFP 912 Query: 553 GD--PGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 GD P DN +G GA+G GP G GP G +GP GP Sbjct: 913 GDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGP 953 Score = 245 bits (625), Expect = 2e-64 Identities = 140/322 (43%), Positives = 178/322 (55%), Gaps = 23/322 (7%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDL-GPVGYQGMKGEKGSRGEKGSR 313 A+G PGL G G +G G G PG KGE G+ G G GP G G +G G RG++G Sbjct: 1301 AQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEP 1360 Query: 314 GPKGYKGEKGKRGIDGVDGVKGEMGYPG---LPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370 G GY G++G +G+ G G +G+ G+PG PG KGS G +G +G G G PG G++ Sbjct: 1361 GDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQ 1420 Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGER 430 G +G PG G GR G G +G +G PG G G++GE GD+G+PGP G G+RG PG Sbjct: 1421 GLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVA 1480 Query: 431 G---PRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487 G +G PG +G G PG+ GP G +G EG G+PG+ GE G KG GD G G Sbjct: 1481 GLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGS---KGQPGDSGEMGFP 1537 Query: 488 GARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGF---------PGFPGYPGNRGAP--- 534 G G GP GPPGD G G +G GP G G EG G PG G++G+ Sbjct: 1538 GMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDW 1597 Query: 535 GINGTKGYPGLKGDEGEAGDPG 556 G+ G +G PG +G G G PG Sbjct: 1598 GLQGPRGPPGPRGRPGPPGPPG 1619 Score = 164 bits (416), Expect = 3e-40 Identities = 120/318 (37%), Positives = 139/318 (43%), Gaps = 96/318 (30%) Query: 347 GSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEK 406 GS F + GPPGPKGD G G G PG PG PG + Sbjct: 616 GSTPFPLLMGPPGPKGDCGL------------------------PGPPGLPGLPGIPGAR 651 Query: 407 GEA------GDEGNPGP------------------DGAPGERGGPGERGPRGTPGTRGPR 442 G G+ G PGP DGA G+ G PG G G PG +G + Sbjct: 652 GPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHK 711 Query: 443 GDPGEAGPQGDQGREGPVGVPGD---------PGEAGPIGPKGYRGD------EGPPGSE 487 G PG AG G+QG+ GP G PG PG G GPKG RG G PGS+ Sbjct: 712 GYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSD 771 Query: 488 GARGAP------GPAGPPGDPGLMGERGEDGPAGN----GTEGFPGFP------------ 525 G RG P G G PG PG+ GERG G GN G G PG P Sbjct: 772 GERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPI 831 Query: 526 GYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNN-----DIAPRGVKGAKGYRGPEGP- 579 GYPG +G G+ G+ G PGLKGD+GE G PG + D +G+ G G RG GP Sbjct: 832 GYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPL 891 Query: 580 -----QGPPGHQGPPGPD 592 +G G GPPGP+ Sbjct: 892 GKVGDKGSIGFPGPPGPE 909 Score = 163 bits (413), Expect = 7e-40 Identities = 97/220 (44%), Positives = 112/220 (50%), Gaps = 12/220 (5%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 +G G G PG G +G GLPG +G G G G GP G G G+ G +GE+G G Sbjct: 1405 KGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGD 1464 Query: 316 KGYKGEKGKRGIDGVDGV---------KGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366 G G GKRG GV G+ KGE G PG G G G +G G PG +G+PG+ Sbjct: 1465 PGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGS 1524 Query: 367 FGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGG 426 G G+ GE G G AG G GP GD G G GP G G G EG GP G G G Sbjct: 1525 KGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGL 1584 Query: 427 PGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDP 466 P GP+G G+RG G G GP G +GR GP G PG P Sbjct: 1585 P---GPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGP 1621 Score = 159 bits (403), Expect = 1e-38 Identities = 102/290 (35%), Positives = 124/290 (42%), Gaps = 86/290 (29%) Query: 257 GPPGLRGDPGFEGERGKPGLPGE---------KGEAGDPGRPGDLGPVGYQGMKGEKGSR 307 GPPG RG G G+RG+PG PG +G+ G G+PG GP G+ G KG KG+ Sbjct: 1343 GPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAE 1402 Query: 308 GEKGSRG------------------PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSP 349 G KG +G P+G G +G GI G DG+ G G G G +G Sbjct: 1403 GPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDD 1462 Query: 350 GFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEA 409 G G GP G +G+PG GL G +G PG GE+G PG GP G G G G PG +GE Sbjct: 1463 GDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEP 1522 Query: 410 GDEGNPG---------------PDGAPGERGGPGERGPRGTPGTRG-------------- 440 G +G PG P G PG+ G G +GPRG PG G Sbjct: 1523 GSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPS 1582 Query: 441 -------------------------PRGDPGEAGPQGDQGREGPVGVPGD 465 PRG PG GP G GP+ + D Sbjct: 1583 GLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPG-----GPIQLQQD 1627 Score = 53.9 bits (128), Expect = 8e-07 Identities = 32/80 (40%), Positives = 38/80 (47%), Gaps = 18/80 (22%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312 Q RGPPGL G G G G LGP G G KG+KGSRG+ G Sbjct: 1558 QGPRGPPGLMGKEGIVGPL------------------GILGPSGLPGPKGDKGSRGDWGL 1599 Query: 313 RGPKGYKGEKGKRGIDGVDG 332 +GP+G G +G+ G G G Sbjct: 1600 QGPRGPPGPRGRPGPPGPPG 1619 >gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] Length = 1073 Score = 300 bits (769), Expect = 4e-81 Identities = 161/349 (46%), Positives = 192/349 (55%), Gaps = 20/349 (5%) Query: 251 ECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310 +C P GPPGL G PGF+G++G PG PG +G G G G G G G+ G +GS+GE+ Sbjct: 563 DCPP--GPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGER 620 Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370 G+ G G KG++G G+ G G G G PG G G+ G GIQG PG +G PG G Sbjct: 621 GADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPS 680 Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQPGEPG---------PPGEKGEAGDEGNPGPDGAP 421 G G PG +G+ GR G GP G+ G+ GEPG PPG KG GD G PGP G Sbjct: 681 GLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGES 740 Query: 422 GERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE 481 G G PG+ G G G GP G G GP+G G+ G PG PGE GP G G +G + Sbjct: 741 GAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGS---PGSPGEPGPSGTPGQKGSK 797 Query: 482 GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKG 541 G GS G G GP GPPG+PG G G++G G PG PG+ G RG PGI G KG Sbjct: 798 GENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGK-----PGEPGFKGERGDPGIKGDKG 852 Query: 542 YPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 PG KG G+ G PG + G +G G GP GP GPPG G PG Sbjct: 853 PPGGKGQPGDPGIPGHKGH-TGLMGPQGLPGENGPVGPPGPPGQPGFPG 900 Score = 290 bits (743), Expect = 4e-78 Identities = 168/379 (44%), Positives = 194/379 (51%), Gaps = 54/379 (14%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAG------DPGRPGDLGPVGYQGMKGEKGSRGEK 310 G PGLRG PG +GERG+ G GE+G G DPG PG GP G +G GE G RG Sbjct: 419 GAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSP 477 Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGY--------------PGLPGCKGSPGFDGIQG 356 G GP G KG++G GI G G +G+ G G PG +G PGF G QG Sbjct: 478 GLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQG 537 Query: 357 PPG------------------------PKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSG 392 P G P G PG GL G KG+ G G+ GR G+ G G Sbjct: 538 PAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKG 597 Query: 393 DEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQG 452 + G PG PGPPG AG +G+ G GA GE G G++G G PG GP G+PG G G Sbjct: 598 EAGPPGLPGPPGI---AGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADG 654 Query: 453 DQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDG 512 G GP G+ G PG+ GP GP+G G G PG EG G G GPPG+PG GE G G Sbjct: 655 IAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPG 714 Query: 513 PAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKG 572 P G G PGF G+ G+ GAPG G G GL G EG G GD P G +G +G Sbjct: 715 P--EGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTG----PTGPQGPQG 768 Query: 573 YRGPEGPQGPPGHQGPPGP 591 RGP G G PG G PGP Sbjct: 769 PRGPPGKNGSPGSPGEPGP 787 Score = 286 bits (732), Expect = 7e-77 Identities = 181/442 (40%), Positives = 211/442 (47%), Gaps = 98/442 (22%) Query: 248 CSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGD---PGRPGDLGPV------GYQ 298 C + A G L G+PG GE G PG PG +GE G+ GRPG+ G G+ Sbjct: 235 CILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFP 294 Query: 299 GMKGEKGSRGEKGSRGPKGYKGEKGKRG----------------------IDGVDGVKGE 336 G++GEKG +GEKG G G KG++G++G + G G KGE Sbjct: 295 GVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGE 354 Query: 337 MGYPGL---PGCKGSPGFDGIQ---GPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGP 390 G PGL PG +G PG G Q GPPG KG GA G G G PGA G G PG SGP Sbjct: 355 KGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGP 414 Query: 391 SGDEGQPGEPGPP------GEKGEAGDEGNPGPDGAPGERGGPGERGP--RGTPGTRGPR 442 G G PG G P GEKG AG+EG+PGP G G+ G PG GP +G G G R Sbjct: 415 PGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLR 474 Query: 443 GDPGEAGPQGDQGREGPVGVPGDPGE--------AGPIGPKGYRGDEGPPGSEGARGAPG 494 G PG GP G +G G G+PG PG AGP GP G GD+G PGS G G PG Sbjct: 475 GSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPG 534 Query: 495 ------------------------------PAGPPGDPGLMGERGEDG----PAGNGTEG 520 P GPPG PGL G +G+ G P GTEG Sbjct: 535 PQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEG 594 Query: 521 FPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNN-----------DIAPRGVKG 569 G G PG G PGI G +G G +G +GE G GD + + P G G Sbjct: 595 KKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADG 654 Query: 570 AKGYRGPEGPQGPPGHQGPPGP 591 G GP G QG PG +GPPGP Sbjct: 655 IAGAAGPPGIQGSPGKEGPPGP 676 Score = 283 bits (725), Expect = 4e-76 Identities = 180/435 (41%), Positives = 205/435 (47%), Gaps = 98/435 (22%) Query: 256 RGPPGLRGDPGFEGERGKPGL---PGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312 RG GL G PG GE G+ GL PGEKGEAG PG PG G G +G +GEKG G G Sbjct: 255 RGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGL 314 Query: 313 RGPKGYKGEKGKRGIDGVDGV-------------------KGEMGYPGLPGCKGSPGFDG 353 +G +G KGE G G G+ G KG+ G PG PG +G PG G Sbjct: 315 KGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELG 374 Query: 354 IQGPPGP---KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPG------ 404 QGP GP KG GA G G G PGA G G PG SGP G G PG G PG Sbjct: 375 PQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERG 434 Query: 405 EKGEAGDEGNPGPDGAPGERGGPGERGP--RGTPGTRGPRGDPGEAGPQGDQGREGPVGV 462 EKG AG+EG+PGP G G+ G PG GP +G G G RG PG GP G +G G G+ Sbjct: 435 EKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGI 494 Query: 463 PGDPGE--------AGPIGPKGYRGDEGPPGSEGARGAPGPAGP---------------- 498 PG PG AGP GP G GD+G PGS G G PGP GP Sbjct: 495 PGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDIN 554 Query: 499 --------------PGDPGLMGERGEDG----PAGNGTEGFPGFPGYPGNRGAPGINGTK 540 PG PGL G +G+ G P GTEG G G PG G PGI G + Sbjct: 555 LLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQ 614 Query: 541 GYPGLKGDEGEAGDPGDDNND-----------------------IAPRGVKGAKGYRGPE 577 G G +G +GE G GD + P G++G+ G GP Sbjct: 615 GSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPP 674 Query: 578 GPQGPPGHQGPPGPD 592 GPQGP G G PG + Sbjct: 675 GPQGPSGLPGIPGEE 689 Score = 279 bits (713), Expect = 1e-74 Identities = 158/367 (43%), Positives = 185/367 (50%), Gaps = 43/367 (11%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGR--PGDLGPVGYQGMKGEKGSRGEKGSR 313 RG PGL G G +G+RG PG+PG G GDPG G GP G G KG GSRG G Sbjct: 474 RGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFP 533 Query: 314 GPKGYKGEKGKR------------------------GIDGVDGVKGEMGYPGLPGCKGSP 349 GP+G G G G+ G+ G KG+ G PG PG +G+ Sbjct: 534 GPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTE 593 Query: 350 GFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEG---QPGEPGPPGEK 406 G G GPPG G PG G +G +GE GADGE G+ G G G G PG PGPPG Sbjct: 594 GKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGAD 653 Query: 407 GEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDP 466 G AG G PG G+PG+ G PG +GP G PG G G G G G G G G PG P Sbjct: 654 GIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLP 713 Query: 467 GEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFP 525 G G GP G++G G G+ G RG G G PG GL G+ G+ GP G G +G G P Sbjct: 714 GPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPP 773 Query: 526 GYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGH 585 G G+ G+PG G G PG KG +GE G PG G+ GP GP G PG Sbjct: 774 GKNGSPGSPGEPGPSGTPGQKGSKGENGSPG-------------LPGFLGPRGPPGEPGE 820 Query: 586 QGPPGPD 592 +G PG + Sbjct: 821 KGVPGKE 827 Score = 277 bits (708), Expect = 4e-74 Identities = 168/403 (41%), Positives = 192/403 (47%), Gaps = 78/403 (19%) Query: 255 ARGPPGLRGDPGFEGE---RGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG 311 A GPPG++G PG EG +G GLPG GE G GR G GP G G GE G G +G Sbjct: 658 AAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEG 717 Query: 312 SRGPKGYKGEKGKRGIDGVDGVKGEMGYPG---LPGCKGSPGFDGIQGPPGPKGDPGAFG 368 +RGP G+KG G G G G G MG PG LPG G G G QGP GP+G PG G Sbjct: 718 ARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNG 777 Query: 369 LKGEKGEPGADGEAGRPGSSGPSGDEGQPG------EPGPPGEKGEAGDEGNPGPDGAPG 422 G GEPG G G+ GS G +G G PG PG PGEKG G EG PG G PG Sbjct: 778 SPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPG 837 Query: 423 ---ERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY-- 477 ERG PG +G +G PG +G GDPG G +G G GP G+PG+ G GP GP G Sbjct: 838 FKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPG 897 Query: 478 ---------------------------------------------RGDEGPPGSEGARGA 492 +G GPPG G G Sbjct: 898 FPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGL 957 Query: 493 PGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGD 548 PG AGP G+PG G+ G +GP+G G G G PG PG G+ G G PG+ G Sbjct: 958 PGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG----VGLRGEMGPPGIPGQ 1013 Query: 549 EGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 GE G D G+ G G +G GP G PG GPPGP Sbjct: 1014 PGEPGYAKD--------GLPGIPGPQGETGPAGHPGLPGPPGP 1048 Score = 276 bits (705), Expect = 9e-74 Identities = 164/417 (39%), Positives = 195/417 (46%), Gaps = 87/417 (20%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP---------------VGYQGMK 301 GPPG+ G G +GERG G G+KG+ G PG PG +GP G G++ Sbjct: 606 GPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQ 665 Query: 302 GEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361 G G G G +GP G G G+ G +G DG G G PG G G PG +G +GPPG K Sbjct: 666 GSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFK 725 Query: 362 GDPGAFGLKGEKGE------PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP 415 G G G G +GE PG +G G+ G +GP+G +G G GPPG+ G G G P Sbjct: 726 GHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEP 785 Query: 416 GPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475 GP G PG++G GE G G PG GPRG PGE G +G G+EG G PG+PG G G Sbjct: 786 GPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDP 845 Query: 476 GYRGDEGPPGSEGARGAPG------------------------PAGPPGDPGLMGERGED 511 G +GD+GPPG +G G PG P GPPG PG G RGE Sbjct: 846 GIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGES 905 Query: 512 -----------------------------GPA-GNGTEGFPGFPGYPGNRGAPGINGTKG 541 PA ++G PG PG PG G PG G G Sbjct: 906 PSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMG 965 Query: 542 YPGLKGDEGEAGDPGDDNNDIAPRGVKGAK--------GYRGPEGPQGPPGHQGPPG 590 PG G G G G I P+G +GAK G RG GP G PG G PG Sbjct: 966 EPGRPGQGGLEGPSG----PIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPG 1018 Score = 272 bits (696), Expect = 1e-72 Identities = 174/453 (38%), Positives = 206/453 (45%), Gaps = 114/453 (25%) Query: 251 ECQPARGPPGLRGD----------PGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGM 300 E PA GPPGL G PG +G +G+ G PG GE G GRPG+LGP G G Sbjct: 323 EAGPA-GPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGP 381 Query: 301 KGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGC---------KGSPGF 351 G KG G G+ G G G G G G G G +G PGL G KG+ G Sbjct: 382 PGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGE 441 Query: 352 DGIQGPPGPKGDPGAFGL-----KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEK 406 +G GP GP+GDPGA GL KG+ GEPG G G PG G GD G PG PG PG + Sbjct: 442 EGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSR 501 Query: 407 GEAGD--EGNPGPDGAPGERGGPGERGPRGTPGTRGPRG--------------------- 443 G+ G G PGP G PG++G PG RG G PG +GP G Sbjct: 502 GDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVC 561 Query: 444 ------------------------DPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRG 479 PG G +G +G GP G+PG PG AGP G +G RG Sbjct: 562 NDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERG 621 Query: 480 DEGPPGSEGARGAPG------PAGPP------------GDPGLMGERGEDGPAG------ 515 +G G +G +G PG P G P G PG+ G G++GP G Sbjct: 622 ADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSG 681 Query: 516 ----------NGTEGFPGFPGYPGNRGAPGI---NGTKGYPGLKGDEGEAGDPGDDNNDI 562 G +G PG PG PG G PG+ G +G PG KG G++G PG Sbjct: 682 LPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESG 741 Query: 563 A-----PRGVKGAKGYRGPEGPQGPPGHQGPPG 590 A G+ G G GP GPQGP G +GPPG Sbjct: 742 AMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPG 774 Score = 237 bits (604), Expect = 5e-62 Identities = 144/331 (43%), Positives = 165/331 (49%), Gaps = 19/331 (5%) Query: 296 GYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQ 355 G + + GE G RGE G G G +GE G++G+ G G KGE G PG PG PG G + Sbjct: 244 GLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGF---PGVRGEK 300 Query: 356 GPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSG----DEGQPGEPGPPGEKGEAGD 411 G G KG+ G GLKG++GE G G AG PG G + PGE GP GEKG+ G Sbjct: 301 GDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGL 360 Query: 412 EGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEA---GPQGDQGREGPVGVPGDPGE 468 G PG G PGE G G GP G G G G PG A G G G GP G PG G Sbjct: 361 PGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGA 420 Query: 469 AGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYP 528 G G G G+ G G+ G G+PGP GP GDP G G GP G G +G PG G P Sbjct: 421 PGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDP---GAPGLPGPPGKGKDGEPGLRGSP 477 Query: 529 GNRGAPGINGTKGYPGLKGDEGEAGDPG-DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQG 587 G G G G +G PG+ G G GDPG P G G KG G G G PG QG Sbjct: 478 GLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQG 537 Query: 588 PPGPDECEIL----DI-IMKMCSCCECKCGP 613 P G D L DI ++ C +C GP Sbjct: 538 PAGRDGLSSLLSPGDINLLAKDVCNDCPPGP 568 Score = 218 bits (556), Expect = 2e-56 Identities = 131/334 (39%), Positives = 158/334 (47%), Gaps = 56/334 (16%) Query: 255 ARGPPGLRGDPGFEGE---------RGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKG 305 A G PG G PG +G+ +G G PG+ G G PG PG G G +G KGE G Sbjct: 742 AMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENG 801 Query: 306 SRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPG 365 S G G GP+G GE G++G+ G +GV G+ G PG G +G PG G +GPPG KG PG Sbjct: 802 SPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPG 861 Query: 366 AFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEA---------------- 409 G+ G KG G G G PG +GP G G PG+PG PG +GE+ Sbjct: 862 DPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGK 921 Query: 410 -------------------GDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGP 450 +G PGP G PG+ G PG GP G PG G G G +GP Sbjct: 922 QLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGP 981 Query: 451 QGDQGREGPVGVPGDPG-----EAGPIGPKGYRGD-----EGPPGSEGARGAPGPAGPPG 500 G +G G G PG PG E GP G G G+ +G PG G +G GPAG PG Sbjct: 982 IGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPG 1041 Query: 501 DPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAP 534 PG G G+ P + F PGN P Sbjct: 1042 LPGPPGPPGQCDP--SQCAYFASLAARPGNVKGP 1073 Score = 210 bits (535), Expect = 5e-54 Identities = 130/320 (40%), Positives = 156/320 (48%), Gaps = 42/320 (13%) Query: 299 GMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPP 358 G +G R + + K G + ++G G +GE G PG PG +G G G+ G P Sbjct: 220 GTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRP 279 Query: 359 GPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPD 418 G EKGE G G G PG G GD+G+ GE G PG KG+ G++G GP Sbjct: 280 G------------EKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPA 327 Query: 419 G----------------APGERGGPGERGPRGTPGTRGPRGDPGEAGPQGD------QGR 456 G PGE+G GE+G G PG G +G PGE GPQG +G+ Sbjct: 328 GPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQ 387 Query: 457 EGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGA---RGAPGPAGPPGDPGLMGERGEDGP 513 EG G PG G G G G G GPPGS GA RG PG G G+ G GE G GP Sbjct: 388 EGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGP 447 Query: 514 AG-NGTEGFPGFPGYP--GNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGA 570 G G G PG PG P G G PG+ G+ G PG G +G+ G PG + RG G Sbjct: 448 VGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSP-GSRGDPGI 506 Query: 571 KGYRGPEGPQGPPGHQGPPG 590 G GP GP GPPG +G PG Sbjct: 507 -GVAGPPGPSGPPGDKGSPG 525 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 300 bits (769), Expect = 4e-81 Identities = 161/349 (46%), Positives = 192/349 (55%), Gaps = 20/349 (5%) Query: 251 ECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310 +C P GPPGL G PGF+G++G PG PG +G G G G G G G+ G +GS+GE+ Sbjct: 1116 DCPP--GPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGER 1173 Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370 G+ G G KG++G G+ G G G G PG G G+ G GIQG PG +G PG G Sbjct: 1174 GADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPS 1233 Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQPGEPG---------PPGEKGEAGDEGNPGPDGAP 421 G G PG +G+ GR G GP G+ G+ GEPG PPG KG GD G PGP G Sbjct: 1234 GLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGES 1293 Query: 422 GERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE 481 G G PG+ G G G GP G G GP+G G+ G PG PGE GP G G +G + Sbjct: 1294 GAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGS---PGSPGEPGPSGTPGQKGSK 1350 Query: 482 GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKG 541 G GS G G GP GPPG+PG G G++G G PG PG+ G RG PGI G KG Sbjct: 1351 GENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGK-----PGEPGFKGERGDPGIKGDKG 1405 Query: 542 YPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 PG KG G+ G PG + G +G G GP GP GPPG G PG Sbjct: 1406 PPGGKGQPGDPGIPGHKGH-TGLMGPQGLPGENGPVGPPGPPGQPGFPG 1453 Score = 291 bits (745), Expect = 2e-78 Identities = 165/391 (42%), Positives = 200/391 (51%), Gaps = 62/391 (15%) Query: 256 RGPPGLRGDPGFEGERGK------PGLPGEKGEAGDPG-----RPGDL------------ 292 +G PG RG PGF G +G PG PGE+G G PG PGD+ Sbjct: 1059 KGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCP 1118 Query: 293 -GPVGYQGM---KGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGC--- 345 GP G G+ KG+KG G+ G G +G KGE G G+ G G+ G G G G Sbjct: 1119 PGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGE 1178 Query: 346 ------KGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE 399 +G PG G GPPG G PGA G+ G G PG G PG GP G +G G Sbjct: 1179 VGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGS---PGKEGPPGPQGPSGL 1235 Query: 400 PGPPGEKGEAGDEGNPGPDGAPGERGGPGERGP---RGTPGTRGPRGDPGEAGPQGDQGR 456 PG PGE+G+ G +G PGP G PG+ G PG GP RG PG +G GD G GP+G+ G Sbjct: 1236 PGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGA 1295 Query: 457 ---EGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDG- 512 G G+PG G+ GP GP+G +G GPPG G+ G+PG GP G PG G +GE+G Sbjct: 1296 MGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGS 1355 Query: 513 ------------PAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNN 560 P G +G PG G PG G PG G +G PG+KGD+G G G + Sbjct: 1356 PGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGD 1415 Query: 561 DIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G+ G KG+ G GPQG PG GP GP Sbjct: 1416 P----GIPGHKGHTGLMGPQGLPGENGPVGP 1442 Score = 282 bits (722), Expect = 1e-75 Identities = 163/357 (45%), Positives = 189/357 (52%), Gaps = 24/357 (6%) Query: 257 GPPGLRGD----PGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312 GPPG+ G G +GE+G PG G +G G PG G +GP G G G +G RG+KG Sbjct: 641 GPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGD 700 Query: 313 RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK-- 370 GP G G G +G G GV G G G PG G GF G GPPGP G PG G Sbjct: 701 MGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGP 760 Query: 371 ----GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGG 426 G KGEPG GE G PG G G+ G+ G G PGEKGEAG G PG G GE+G Sbjct: 761 PGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGD 820 Query: 427 PGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGV----PGDPGEAGPIGPKGYRGDEG 482 GE+G G PG +G RG+ GEAGP G G G + P PGE GP G KG G G Sbjct: 821 QGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPG 880 Query: 483 PPGSEGARGAPGPAGPPGDPGLMGERGEDG-------PAGNGTEGFPGFPGYPGNRGAPG 535 PG +G G GP GP G PG G+ G G P G G PG G PG+ GAPG Sbjct: 881 EPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPG 940 Query: 536 INGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGP--EGPQGPPGHQGPPG 590 + GT G G +G++G AG+ G + PRG GA G GP +G G PG +G PG Sbjct: 941 LRGTPGKDGERGEKGAAGEEGSP-GPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPG 996 Score = 280 bits (715), Expect = 6e-75 Identities = 165/377 (43%), Positives = 189/377 (50%), Gaps = 44/377 (11%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDL------GPVGYQGMKGEKGS 306 Q +G G G PG G G G+ GE GE G+PG PG++ GP G G G G+ Sbjct: 526 QGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGA 585 Query: 307 RGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366 G +G RG KG +GEKG+RG+DG G G+ G G PG G G G +G GP G PG Sbjct: 586 PGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGV 645 Query: 367 -------FGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDG 419 GLKGE+G PG G G PG G G G G GPPG +G G +G+ GP G Sbjct: 646 PGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPG 705 Query: 420 APGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRG 479 PG G G GP G PG GP G PG G G G+ GP G G PG+ GP GP Sbjct: 706 IPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGP----- 760 Query: 480 DEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFPGYPGNRGAPG 535 GPPG++G G G G PG PGL GE GE G AG G G PG PG+PG RG G Sbjct: 761 -PGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKG 819 Query: 536 INGTK---GYPGLKGDEGEAGDPGDDN------------------NDIAPRGVKGAKGYR 574 G K G PGLKGD GE G+ G + P+G KG G Sbjct: 820 DQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLP 879 Query: 575 GPEGPQGPPGHQGPPGP 591 G G QG PG GP GP Sbjct: 880 GEPGLQGRPGELGPQGP 896 Score = 277 bits (708), Expect = 4e-74 Identities = 168/403 (41%), Positives = 192/403 (47%), Gaps = 78/403 (19%) Query: 255 ARGPPGLRGDPGFEGE---RGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG 311 A GPPG++G PG EG +G GLPG GE G GR G GP G G GE G G +G Sbjct: 1211 AAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEG 1270 Query: 312 SRGPKGYKGEKGKRGIDGVDGVKGEMGYPG---LPGCKGSPGFDGIQGPPGPKGDPGAFG 368 +RGP G+KG G G G G G MG PG LPG G G G QGP GP+G PG G Sbjct: 1271 ARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNG 1330 Query: 369 LKGEKGEPGADGEAGRPGSSGPSGDEGQPG------EPGPPGEKGEAGDEGNPGPDGAPG 422 G GEPG G G+ GS G +G G PG PG PGEKG G EG PG G PG Sbjct: 1331 SPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPG 1390 Query: 423 ---ERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY-- 477 ERG PG +G +G PG +G GDPG G +G G GP G+PG+ G GP GP G Sbjct: 1391 FKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPG 1450 Query: 478 ---------------------------------------------RGDEGPPGSEGARGA 492 +G GPPG G G Sbjct: 1451 FPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGL 1510 Query: 493 PGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGD 548 PG AGP G+PG G+ G +GP+G G G G PG PG G+ G G PG+ G Sbjct: 1511 PGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG----VGLRGEMGPPGIPGQ 1566 Query: 549 EGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 GE G D G+ G G +G GP G PG GPPGP Sbjct: 1567 PGEPGYAKD--------GLPGIPGPQGETGPAGHPGLPGPPGP 1601 Score = 276 bits (705), Expect = 9e-74 Identities = 164/417 (39%), Positives = 195/417 (46%), Gaps = 87/417 (20%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP---------------VGYQGMK 301 GPPG+ G G +GERG G G+KG+ G PG PG +GP G G++ Sbjct: 1159 GPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQ 1218 Query: 302 GEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361 G G G G +GP G G G+ G +G DG G G PG G G PG +G +GPPG K Sbjct: 1219 GSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFK 1278 Query: 362 GDPGAFGLKGEKGE------PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP 415 G G G G +GE PG +G G+ G +GP+G +G G GPPG+ G G G P Sbjct: 1279 GHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEP 1338 Query: 416 GPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475 GP G PG++G GE G G PG GPRG PGE G +G G+EG G PG+PG G G Sbjct: 1339 GPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDP 1398 Query: 476 GYRGDEGPPGSEGARGAPG------------------------PAGPPGDPGLMGERGED 511 G +GD+GPPG +G G PG P GPPG PG G RGE Sbjct: 1399 GIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGES 1458 Query: 512 -----------------------------GPA-GNGTEGFPGFPGYPGNRGAPGINGTKG 541 PA ++G PG PG PG G PG G G Sbjct: 1459 PSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMG 1518 Query: 542 YPGLKGDEGEAGDPGDDNNDIAPRGVKGAK--------GYRGPEGPQGPPGHQGPPG 590 PG G G G G I P+G +GAK G RG GP G PG G PG Sbjct: 1519 EPGRPGQGGLEGPSG----PIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPG 1571 Score = 273 bits (698), Expect = 6e-73 Identities = 185/481 (38%), Positives = 214/481 (44%), Gaps = 145/481 (30%) Query: 257 GPPGLRGDPGFEGERG---KPGLPGEKGEAGDPGRPGDLGPVG------YQGMKGEKGSR 307 GPPG +G+PG GE G KPGL GE GE G GRPG+ G G + G++GEKG + Sbjct: 762 GPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQ 821 Query: 308 GEKGSRGPKGYKGEKGKRG----------------------IDGVDGVKGEMGYPGLPG- 344 GEKG G G KG++G++G + G G KGE G PGLPG Sbjct: 822 GEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGE 881 Query: 345 --CKGSPGFDGIQGPPGP---KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE 399 +G PG G QGP GP KG GA G G G PGA G G PG SGP G G PG Sbjct: 882 PGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGL 941 Query: 400 PGPPG------EKGEAGDEGNPGP--------------------DGAPGERGGPGERGPR 433 G PG EKG AG+EG+PGP DG PG RG PG GP Sbjct: 942 RGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPL 1001 Query: 434 GT-----------------------------PGTRGPRGDPG--EAGPQGDQGREGPVGV 462 GT PG+ G RGDPG AGP G G G G Sbjct: 1002 GTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGS 1061 Query: 463 PGDPGEAGPIGPKGYRGDEGPPGSEGARGAPG------------------------PAGP 498 PG G G GP+G G +G PG+ G RG PG P GP Sbjct: 1062 PGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGP 1121 Query: 499 PGDPGLMGERGEDG----PAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGD 554 PG PGL G +G+ G P GTEG G G PG G PGI G +G G +G +GE G Sbjct: 1122 PGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQ 1181 Query: 555 PGDDNND-----------------------IAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 GD + P G++G+ G GP GPQGP G G PG Sbjct: 1182 KGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGE 1241 Query: 592 D 592 + Sbjct: 1242 E 1242 Score = 272 bits (696), Expect = 1e-72 Identities = 163/375 (43%), Positives = 187/375 (49%), Gaps = 53/375 (14%) Query: 257 GPPGLRGDPGFEGERGKPGLPGE-----------------------KGEAGDPGRPGD-- 291 GPPG +G G G RG PGLPG KG+ G PG PG Sbjct: 979 GPPG-KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPG 1037 Query: 292 ------LGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGC 345 +G G G G G +G GSRG G+ G +G G DG G GE G PG PG Sbjct: 1038 SRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGL 1097 Query: 346 KG--SPGFDGIQG-------PPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQ 396 SPG + PPGP G PG G KG+KG P G+ GR G+ G G+ G Sbjct: 1098 SSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVP---GKPGREGTEGKKGEAGP 1154 Query: 397 PGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGR 456 PG PGPP G AG +G+ G GA GE G G++G G PG GP G+PG G G G Sbjct: 1155 PGLPGPP---GIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGA 1211 Query: 457 EGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN 516 GP G+ G PG+ GP GP+G G G PG EG G G GPPG+PG GE G GP Sbjct: 1212 AGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGP--E 1269 Query: 517 GTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGP 576 G G PGF G+ G+ GAPG G G GL G EG G G D P G +G +G RGP Sbjct: 1270 GARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDG----DTGPTGPQGPQGPRGP 1325 Query: 577 EGPQGPPGHQGPPGP 591 G G PG G PGP Sbjct: 1326 PGKNGSPGSPGEPGP 1340 Score = 271 bits (693), Expect = 2e-72 Identities = 156/378 (41%), Positives = 184/378 (48%), Gaps = 46/378 (12%) Query: 248 CSFECQPARGPPGLRGDPGFEGERGKPGL-----PGEKGEAGDPGRPGDLGPVGY---QG 299 C+ Q +G G G PG G RG PG+ PG G GD G PG G G+ QG Sbjct: 1016 CALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQG 1075 Query: 300 MKGEKGSRGEKGSRGPKGYKG---------------------EKGKRGIDGVDGVKGEMG 338 G G+ G G RGP G G G G+ G+ G KG+ G Sbjct: 1076 PAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKG 1135 Query: 339 YPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEG--- 395 PG PG +G+ G G GPPG G PG G +G +GE GADGE G+ G G G G Sbjct: 1136 VPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMG 1195 Query: 396 QPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQG 455 PG PGPPG G AG G PG G+PG+ G PG +GP G PG G G G G G G Sbjct: 1196 PPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPG 1255 Query: 456 REGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG 515 G G PG PG G GP G++G G G+ G RG G G PG GL G+ G+ GP G Sbjct: 1256 EPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTG 1315 Query: 516 -NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYR 574 G +G G PG G+ G+PG G G PG KG +GE G PG G+ Sbjct: 1316 PQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPG-------------LPGFL 1362 Query: 575 GPEGPQGPPGHQGPPGPD 592 GP GP G PG +G PG + Sbjct: 1363 GPRGPPGEPGEKGVPGKE 1380 Score = 270 bits (691), Expect = 4e-72 Identities = 172/419 (41%), Positives = 203/419 (48%), Gaps = 82/419 (19%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GPPG G PG GE G PG PG G G PG+ G GP G G KGE G RGE G G Sbjct: 723 GPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKP 782 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376 G +GE G++G+ G G KGE G PG +PGF G++G G +G+ KGE G P Sbjct: 783 GLRGEIGEQGLAGRPGEKGEAGLPG------APGFPGVRGEKGDQGE------KGELGLP 830 Query: 377 GADGEAGRPGSSGPSGDEGQPG-------EPGPPGEKGEAGDEGNPGPDGAPGERGGPGE 429 G G+ G G +GP+G G PG P PGE+G G++G+PG G PG +G PGE Sbjct: 831 GLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGE 890 Query: 430 RGPR---------------GTPGTRGPRGDPGEAGPQGDQGREGPVGVP---GDPGEAGP 471 GP+ G PG G G PG G G G G VG P G PG+ G Sbjct: 891 LGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGE 950 Query: 472 IGPKGYRGDEGPPGSEGAR---GAPGPAGPP-----GDPGLMGERGEDGPAG-------- 515 G KG G+EG PG G R GAPG GPP G+PGL G G GP G Sbjct: 951 RGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKV 1010 Query: 516 -------------NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDI 562 G G PG PG PG+RG PGI G G PG G G+ G PG Sbjct: 1011 RGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSGPPGDKGSPGS----- 1064 Query: 563 APRGVKGAKGYRGP---EGPQGPPGHQGPPGPDECEIL----DI-IMKMCSCCECKCGP 613 RG+ G G +GP +G G PG +GPPG L DI ++ C +C GP Sbjct: 1065 --RGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGP 1121 Score = 262 bits (669), Expect = 1e-69 Identities = 167/405 (41%), Positives = 199/405 (49%), Gaps = 85/405 (20%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAG------DPGRPGDLGPVGYQGMKGEKGSRGEK 310 G PGLRG PG +GERG+ G GE+G G DPG PG GP G +G GE G RG Sbjct: 937 GAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSP 995 Query: 311 GSRGPKGYKGEKGK-RGIDG-------VDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKG 362 G GP G K GK RG + V G +G G PG PG +G PG G+ GPPGP G Sbjct: 996 GLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSG 1054 Query: 363 DPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPG---PPGEKGE----------- 408 PG +KG PG+ G G PG GP+G +G PG PG PPG+ G Sbjct: 1055 PPG------DKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINL 1108 Query: 409 -AGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPG 467 A D N P G PG G PG +G +G PG PG G +G +G GP G+PG PG Sbjct: 1109 LAKDVCNDCPPGPPGLPGLPGFKGDKGVPGK------PGREGTEGKKGEAGPPGLPGPPG 1162 Query: 468 EAGPIGPKGYRGDEGPPGSEGARGAPG------PAGPP------------GDPGLMGERG 509 AGP G +G RG +G G +G +G PG P G P G PG+ G G Sbjct: 1163 IAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPG 1222 Query: 510 EDGPAG----------------NGTEGFPGFPGYPGNRGAPGI---NGTKGYPGLKGDEG 550 ++GP G G +G PG PG PG G PG+ G +G PG KG G Sbjct: 1223 KEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTG 1282 Query: 551 EAGDPGDDNNDIA-----PRGVKGAKGYRGPEGPQGPPGHQGPPG 590 ++G PG A G+ G G GP GPQGP G +GPPG Sbjct: 1283 DSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPG 1327 Score = 228 bits (582), Expect = 2e-59 Identities = 136/309 (44%), Positives = 159/309 (51%), Gaps = 50/309 (16%) Query: 332 GVKGEMGYPG---LPGCKGSPGFDGIQGPPGPKGDPGAFGL-------KGEKGEPGADGE 381 G KGEMG G LPG KG G G G PGPKG+ G G+ KGEKG G G Sbjct: 481 GEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGP 540 Query: 382 AGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGP 441 GR GS G G+ G+ GEPG PGE G G +G PG G PG G PG +G RG GTRG Sbjct: 541 PGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGE 600 Query: 442 RGD------PGEAGPQGDQGREGPVGVPGDPGEAGPIGP-------------KGYRGDEG 482 +G+ PG+ G G QGR GP GV G GE G +GP +G +G++G Sbjct: 601 KGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQG 660 Query: 483 PPGSEGARGAPGPA------------GPPGDPGLMGERGEDGPAG-------NGTEGFPG 523 PG G +GAPGP GPPG GL G++G+ GP G G G PG Sbjct: 661 APGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPG 720 Query: 524 FPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDD--NNDIAPRGVKGAKGYRGPEGPQG 581 PG PG G+PG+ G G+PG G G G PG D N P G KG G RG +G G Sbjct: 721 VPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPG 780 Query: 582 PPGHQGPPG 590 PG +G G Sbjct: 781 KPGLRGEIG 789 Score = 218 bits (556), Expect = 2e-56 Identities = 131/334 (39%), Positives = 158/334 (47%), Gaps = 56/334 (16%) Query: 255 ARGPPGLRGDPGFEGE---------RGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKG 305 A G PG G PG +G+ +G G PG+ G G PG PG G G +G KGE G Sbjct: 1295 AMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENG 1354 Query: 306 SRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPG 365 S G G GP+G GE G++G+ G +GV G+ G PG G +G PG G +GPPG KG PG Sbjct: 1355 SPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPG 1414 Query: 366 AFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEA---------------- 409 G+ G KG G G G PG +GP G G PG+PG PG +GE+ Sbjct: 1415 DPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGK 1474 Query: 410 -------------------GDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGP 450 +G PGP G PG+ G PG GP G PG G G G +GP Sbjct: 1475 QLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGP 1534 Query: 451 QGDQGREGPVGVPGDPG-----EAGPIGPKGYRGD-----EGPPGSEGARGAPGPAGPPG 500 G +G G G PG PG E GP G G G+ +G PG G +G GPAG PG Sbjct: 1535 IGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPG 1594 Query: 501 DPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAP 534 PG G G+ P + F PGN P Sbjct: 1595 LPGPPGPPGQCDP--SQCAYFASLAARPGNVKGP 1626 Score = 170 bits (431), Expect = 6e-42 Identities = 99/214 (46%), Positives = 119/214 (55%), Gaps = 16/214 (7%) Query: 388 SGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERG--PRGTPGTRGPRGDP 445 S P+G++G+ G GP G G GD G GP GAPG +G G+ G P G G +G +G Sbjct: 477 SCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQ-GEKGEKGSL 535 Query: 446 GEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLM 505 G GP G G +G G PG+ GE G G G RG +GPPG PGP G G PGL Sbjct: 536 GLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPG------LPGPPGRVGAPGLQ 589 Query: 506 GERGEDGPAGN----GTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNND 561 GERGE G G G +GFPG PG G +G PG +G G G KGD G AG PG + Sbjct: 590 GERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSV 649 Query: 562 IAPRGVKGAKGYRGPEGPQG---PPGHQGPPGPD 592 + G+KG +G GP G QG PPG +GP GP+ Sbjct: 650 VQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPE 683 Score = 61.2 bits (147), Expect = 5e-09 Identities = 45/157 (28%), Positives = 77/157 (49%), Gaps = 20/157 (12%) Query: 609 CKCGPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHS 668 CK DL+F+LD+S S+G ++FE + +V ++D + P ++ GVV+YS Sbjct: 32 CKSVHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTF------EVGPDRTRVGVVRYSD- 84 Query: 669 QMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNR------ 722 + + + +E+K A + L + G T TG+AL+Y + P R Sbjct: 85 --RPTTAFELGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAY 142 Query: 723 --IALVITDGRS-DTQRDTTPLNVLCSPGIQVVSVGI 756 +A+++TDGRS D D GI++ +VG+ Sbjct: 143 KQVAILLTDGRSQDLVLDAAA--AAHRAGIRIFAVGV 177 Score = 58.5 bits (140), Expect = 3e-08 Identities = 60/207 (28%), Positives = 92/207 (44%), Gaps = 33/207 (15%) Query: 829 DITILLDGSASVGSHNFDTTKRFAKRLAERF-LTAGRTDPAHDVRVAVVQYSGTGQQRPE 887 D+ LLD S+SVG +F+ +++ L + F + RT RV VV+YS RP Sbjct: 38 DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRT------RVGVVRYS----DRPT 87 Query: 888 RA-SLQFLQNYTALASAVDAMDFINDATDVNDALGYVT-RFYREASSG-----AAKKRLL 940 A L + + +A + + T+ DAL Y+T R + + G A K+ + Sbjct: 88 TAFELGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAI 147 Query: 941 LFSDGNSQGATPAAIEKAVQEAQRAGIEIFVVVVGRQVNEPHIRVLVTGKTAEYDVAYGE 1000 L +DG SQ + A A RAGI IF V VG + E + K+A Sbjct: 148 LLTDGRSQD----LVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSA-------- 195 Query: 1001 SHLFRVPSYQAL--LRGVFHQTVSRKV 1025 H+F V + A+ +RG + + V Sbjct: 196 -HVFHVSDFNAIDKIRGKLRRRLCENV 221 Score = 32.0 bits (71), Expect = 3.1 Identities = 45/187 (24%), Positives = 78/187 (41%), Gaps = 26/187 (13%) Query: 37 DLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLRDRYYRCDRNLVWNAGALHYSDE 96 DL F+LDTS SV +KV+ + +D DR V G + YSD Sbjct: 38 DLVFLLDTSSSVGKE------DFEKVRQWVANLVDTFE---VGPDRTRV---GVVRYSDR 85 Query: 97 VEIIQGLTRMPGGRDALKSSVDAVKYFGKGTYTDCAIKKGLEQLLV--GGSHLKENKY-- 152 L + G ++ +K++ + Y G T T A++ + G ++ Y Sbjct: 86 PTTAFEL-GLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQ 144 Query: 153 -LIVVTDGHPLEGYKEPCGGLEDAVNEAKHLGVKVFSVAITPDHLEPRLSIIATDHTYRR 211 I++TDG + + DA A G+++F+V + + L+ L IA++ Sbjct: 145 VAILLTDGRSQD-------LVLDAAAAAHRAGIRIFAVGV-GEALKEELEEIASEPKSAH 196 Query: 212 NFTAADW 218 F +D+ Sbjct: 197 VFHVSDF 203 >gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] Length = 1690 Score = 300 bits (767), Expect = 6e-81 Identities = 164/371 (44%), Positives = 193/371 (52%), Gaps = 37/371 (9%) Query: 257 GPPGLRGDPGF-----EGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG 311 G G+ GDP F G+RG G+PG KG GDPG PG GP G G G KG +G +G Sbjct: 754 GQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREG 813 Query: 312 SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKG 371 G G G G G G+ G+ G PG PG G+PG G G GP G G GL G Sbjct: 814 HAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPG 873 Query: 372 EKGEPGADGEAGRPGSSGPSGDEGQPGEPGP------PGEKGEAGDEGNPGPDGAPGERG 425 G PGA G G PG GP GD+G PG PGP PG G G+ G PG +G PG +G Sbjct: 874 LPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKG 933 Query: 426 GPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY---RGDEG 482 PGE+G G PG RG RG G GP GD+G + G PGE GP G G+ RGD+G Sbjct: 934 EPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKG 993 Query: 483 PPGSEGARGAPGPAGPP----GDPGLMGERGEDGPAG----NGTEGFPGFPGYPGNRGAP 534 PG +G RG PG GPP G+PG G+ G GP G G GF GFPG PG++G P Sbjct: 994 TPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEP 1053 Query: 535 GINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVK---------------GAKGYRGPEGP 579 G G G+ G+ G G G+ GD + P G K G +G G +GP Sbjct: 1054 GSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGP 1113 Query: 580 QGPPGHQGPPG 590 +G PG GPPG Sbjct: 1114 RGSPGRPGPPG 1124 Score = 288 bits (738), Expect = 1e-77 Identities = 181/436 (41%), Positives = 203/436 (46%), Gaps = 106/436 (24%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G PG GD GF GERG G PG +G G+PGR GP G+ +GE G +G+ G GP Sbjct: 975 GEPGPPGDDGFPGERGDKGTPGMQGRRGEPGR---YGPPGFH--RGEPGEKGQPGPPGPP 1029 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA-FGLKGEKGE 375 G G G RG G G+ G+ G PG PG G G DG +GP G KGDP + FG G KGE Sbjct: 1030 GPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGE 1089 Query: 376 PG---------ADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGG 426 PG A GE G PG GP G G+PG PG G G GD G PG G PGE G Sbjct: 1090 PGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGD 1149 Query: 427 PGERG-----------------------------------------------PRGTPGTR 439 PG RG P G PG + Sbjct: 1150 PGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLK 1209 Query: 440 GPRGDPGEAG--PQGDQGREGPVGVPGDPGEAGPIG-----PK-----GYRGDEGPPGSE 487 G RGDPG G P G +G++GP G PG G GP G PK G GD+GPPG + Sbjct: 1210 GERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPD 1269 Query: 488 GARGAPGPAG-------------------------PPGDPGLMGERGEDGPAGN-GTEGF 521 G RGAPGP G PPG PG G G DG G G GF Sbjct: 1270 GPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGF 1329 Query: 522 PG------FPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRG 575 PG FPG PG +G PG G KG GL G GE G P D ++ G+ GA G RG Sbjct: 1330 PGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRG 1389 Query: 576 PEGPQGPPGHQGPPGP 591 PEG G PG +GP GP Sbjct: 1390 PEGAMGLPGMRGPSGP 1405 Score = 285 bits (730), Expect = 1e-76 Identities = 161/364 (44%), Positives = 188/364 (51%), Gaps = 37/364 (10%) Query: 257 GPPGL---RGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSR 313 GPPG RG PG G+ G PG PG G G G+PGD+GP G GMKG G G G+ Sbjct: 822 GPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAH 881 Query: 314 GPKGYKGEKGKRGIDGVDGVKGEMG------YPGLPGCKGSPGFDGIQGPPGPKGDPGAF 367 GP G G G G DG+ G G G +PG PG +G PG +G G G G+ G Sbjct: 882 GPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMS 941 Query: 368 GLKGEKGEPGADGEAGRPGSSGPS---GDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGER 424 GL G++G GA G G PG G +G PGEPGPPG+ G G+ G+ G G G R Sbjct: 942 GLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRR 1001 Query: 425 GGPGERGP----RGTPGTRGPRGDPGEAGPQGDQGREGPV---GVPGDPGEAGPIGPKGY 477 G PG GP RG PG +G G PG GP G G G + G+PGD GE G GP G+ Sbjct: 1002 GEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGF 1061 Query: 478 RGDEGPPGSEGAR-------GAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFPG 526 G +G G +G + G PGP G PG PG G G G G G G PG PG Sbjct: 1062 SGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPG 1121 Query: 527 YPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQ 586 PG+ G PG G G PGL+G GE GDPG PRG++G G GP G +GP G Sbjct: 1122 PPGSSGPPGCPGDHGMPGLRGQPGEMGDPG-------PRGLQGDPGIPGPPGIKGPSGSP 1174 Query: 587 GPPG 590 G G Sbjct: 1175 GLNG 1178 Score = 282 bits (722), Expect = 1e-75 Identities = 168/381 (44%), Positives = 201/381 (52%), Gaps = 49/381 (12%) Query: 256 RGPPGLRGDPGFEGERGKPGL---PGEKGEAGDPGRPGDLGPVGYQGMKG---------- 302 +GP GL G PGF GERGKPG PG KGE G+ G G G G +G KG Sbjct: 905 KGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGE 964 Query: 303 -----EKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGC-KGSPGFDGIQG 356 +KG+ GE G G G+ GE+G +G G+ G +GE G G PG +G PG G G Sbjct: 965 MAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPG 1024 Query: 357 PPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSG---------DEGQPGEP----GPP 403 PPGP G PG+ GL+G G PG G+ G PGS GP G +G G+P GPP Sbjct: 1025 PPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPP 1084 Query: 404 GEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVP 463 G KGE G G PG GA GE+G PG +GPRG+PG GP PG +GP G G G G+ Sbjct: 1085 GPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGP---PGSSGPPGCPGDHGMPGLR 1141 Query: 464 GDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG------NG 517 G PGE G GP+G +GD G PG G +G G G G GL G++G G +G G Sbjct: 1142 GQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPG 1201 Query: 518 TEGFPGFPGYPGNRGAPGIN--------GTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKG 569 G PG G G+ G+PGI+ G G PG G G AG G DI G G Sbjct: 1202 PVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPG 1261 Query: 570 AKGYRGPEGPQGPPGHQGPPG 590 +G GP+GP+G PG G PG Sbjct: 1262 DQGPPGPDGPRGAPGPPGLPG 1282 Score = 279 bits (713), Expect = 1e-74 Identities = 172/421 (40%), Positives = 201/421 (47%), Gaps = 89/421 (21%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 +G PG G PG G +G PGLPG G G PG PG GP G G+ G G +G +G G Sbjct: 854 KGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGF 913 Query: 316 KGYKGEKGKRGIDGVDGVKGE---MGYPGLPGCKGSPGFDGIQGPPG------------- 359 G+ GE+GK G +G G KGE G GLPG +G G G GPPG Sbjct: 914 PGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGT 973 Query: 360 -----PKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSG-------DEGQPGEPGPPGEKG 407 P GD G G +G+KG PG G G PG GP G ++GQPG PGPPG G Sbjct: 974 PGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPG 1033 Query: 408 EAG------------DEGNPGPDGAPGERGGPGERGPRGTPGTR-------GPRGDPGE- 447 G D+G PG G PG G G RGP+G G GP+G+PG Sbjct: 1034 STGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSP 1093 Query: 448 --------AGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPG---SEGARGAPGPA 496 +G QG G +GP G PG PG G GP G GD G PG G G PGP Sbjct: 1094 GCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPR 1153 Query: 497 GPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGIN-----GTKGYPGLKGDEG 550 G GDPG+ G G GP+G+ G G G G G +GA G++ G G PGLKG+ G Sbjct: 1154 GLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERG 1213 Query: 551 EAGDPGDDNNDIAPRGVKGAKGYRGPEGPQ-------------------GPPGHQGPPGP 591 + G PG I+P G +G KG GP G GPPG QGPPGP Sbjct: 1214 DPGSPG-----ISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGP 1268 Query: 592 D 592 D Sbjct: 1269 D 1269 Score = 270 bits (690), Expect = 5e-72 Identities = 174/406 (42%), Positives = 186/406 (45%), Gaps = 73/406 (17%) Query: 252 CQPA-RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310 C+P GPPG G PG +G +G GLPG G GDPG PG GP G G G G G K Sbjct: 494 CEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNK 553 Query: 311 GSRGP---KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD---- 363 G++G KG KG+RG DG G +PG PG G G G +G PGP GD Sbjct: 554 GAKGDMVVSRVKGHKGERGPDGPPG------FPGQPGSHGRDGHAGEKGDPGPPGDHEDA 607 Query: 364 -PGAFGLKGEKGEPGADGEAGRPGSS--GPSGDEGQPGEP-------------------- 400 PG G G G PG G G PG GP G+ G PG P Sbjct: 608 TPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTIS 667 Query: 401 ---------GPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQ 451 GPPG G G +G PGP GAPG G G +G GTPGT G PG G Sbjct: 668 CNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDM 727 Query: 452 GDQGREG-----PVGVPGDPGEAGPIGPKGYRGDE-----GPPGSEGARGAPGPAGPPGD 501 GD G G PVG PG PG G G KG GD GPPG G G PG GP GD Sbjct: 728 GDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGD 787 Query: 502 PGLMGERGEDGPAG-------NGTEGFPGFPGYPG------NRGAPGI---NGTKGYPGL 545 PG G G G G G EG GFPG PG RGAPGI G GYPG Sbjct: 788 PGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGS 847 Query: 546 KGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G G G PGD P G+KG G G G GPPG G PGP Sbjct: 848 PGAPGGKGQPGDVGPP-GPAGMKGLPGLPGRPGAHGPPGLPGIPGP 892 Score = 265 bits (678), Expect = 1e-70 Identities = 166/399 (41%), Positives = 191/399 (47%), Gaps = 59/399 (14%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG- 314 RGPPG GD G +G G PG PG G G PG PG G G G G +G G G RG Sbjct: 97 RGPPGAAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGA 156 Query: 315 -----PKGYKGEKGKRG-----IDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDP 364 P G+ GEKG++G + V G++G+ G PGLPG GS G G GP G G+P Sbjct: 157 LGPGGPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEP 216 Query: 365 GAFGLKGEKGEPGADGE--AGRPGSSGPSGDEGQPGEPGPP------------GEKGEAG 410 G G G+ G PG G G G G G+ GQ G PGP GEKG G Sbjct: 217 GLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKG 276 Query: 411 DEGNPGPDGAPGERG--GPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGE 468 G G G PG +G G G +G +G PG GPRGDPG G G G +G +G+ GDPG Sbjct: 277 IPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGL 336 Query: 469 AGPIGPKGYRGDEGPPGSEGARGAP-----GPAGPPGDPGLMGERGEDGPAGN------- 516 G IGPKG G+ G PG G P GP G PG PG GE G+ GP G Sbjct: 337 FGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRP 396 Query: 517 -----------GTEGFPGFPGYPGNRG-------APGINGTKGYPGLKGDEGEAGDPGDD 558 G +GFPG PG PG G APG G G PGL G G G PG Sbjct: 397 GEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSS 456 Query: 559 --NNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPDECE 595 + G +G KG GP G +GP G +G G CE Sbjct: 457 VIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACE 495 Score = 262 bits (669), Expect = 1e-69 Identities = 168/391 (42%), Positives = 191/391 (48%), Gaps = 64/391 (16%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGE--AGDPGRPGDLGPVGYQGMKGE----------- 303 GP G G+PG G G+PG PG KG G G+ GD G VG QG G Sbjct: 208 GPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCL 267 Query: 304 -KGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKG------SPGFDGIQG 356 KG +G KG G G G G++G G+ G KGE G PG PG +G SPGF G++G Sbjct: 268 YKGEKGIKGIPGMVGLPGPPGRKGESGI-GAKGEKGIPGFPGPRGDPGSYGSPGFPGLKG 326 Query: 357 PPGPKGDPGAFGLKGEKGEPGADGEAGRPGS--------SGPSGDEGQPGE--------- 399 G GDPG FGL G KG+PG G G PG GP GD G PG Sbjct: 327 ELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGP 386 Query: 400 PGPPGEKGEAGDE-----GNPGPDGAPGERGGPGERG----PRGTPGTRGPRGDPGEAGP 450 PGPPG G G+ G PGP G PG G PGE G P PG G G PG G Sbjct: 387 PGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGA 446 Query: 451 QGDQGREGP------VGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGA-PGPAGPPGDPG 503 G QG G VG PG G G +GP G RG +G G+EG PGP GPPG PG Sbjct: 447 PGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPG 506 Query: 504 LMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN--ND 561 L G +G G G PG+ G +G PG G +G PGL G G +G PG+ D Sbjct: 507 LPGRQGSKGDLG--------LPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGD 558 Query: 562 IAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592 + VKG KG RGP+GP G PG G G D Sbjct: 559 MVVSRVKGHKGERGPDGPPGFPGQPGSHGRD 589 Score = 259 bits (663), Expect = 7e-69 Identities = 157/375 (41%), Positives = 187/375 (49%), Gaps = 48/375 (12%) Query: 252 CQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGE------KG 305 C G G +G PG +G RG PG PG G +G PG PGD G G +G GE +G Sbjct: 1095 CPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRG 1154 Query: 306 SRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCK--GSPGFDGIQGPPGPKGD 363 +G+ G GP G KG G G++G+ G+KG+ G G G G PG GI G G +GD Sbjct: 1155 LQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGD 1214 Query: 364 PGAFGL-----KGEKGEPGADGEAGRPGSSGPSG----DEGQPGEPGPPGEKGEAGDEGN 414 PG+ G+ +G+KG PG G +G PG +G +G D PG PG G G G G Sbjct: 1215 PGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGA 1274 Query: 415 PGPDGAPGE----RGGPGE---RGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPG 467 PGP G PG RG PG+ GP G PG GP G G G G G++GPVG PG G Sbjct: 1275 PGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQG 1334 Query: 468 EAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGD----------PGLMGERGEDGPAGNG 517 G GP G +G GPPG +G G PGP G PG PGL G G GP G Sbjct: 1335 PHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGP--EG 1392 Query: 518 TEGFPGF--PGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRG 575 G PG P PG +G PG++G +G G+ G G G GD D GY G Sbjct: 1393 AMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGED----------GYPG 1442 Query: 576 PEGPQGPPGHQGPPG 590 GP GP G GP G Sbjct: 1443 GPGPPGPIGDPGPKG 1457 Score = 259 bits (662), Expect = 9e-69 Identities = 174/453 (38%), Positives = 203/453 (44%), Gaps = 108/453 (23%) Query: 247 CCSFECQP---ARGPPGL------------------RGDPGFEGERGKPGLPGEKGEAGD 285 C C P +RGPPG G+ G G+RG PG G+KG+ G Sbjct: 52 CSVCHCVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGP 111 Query: 286 ------------PGRPGDLGPVGYQGMKGEKGSRGEK---------GSRGPKGYKGEKGK 324 PG PG GP G GM G GSRG+ G GP G+ GEKG+ Sbjct: 112 TGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGE 171 Query: 325 RG-----IDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGAD 379 +G + V G++G+ G PGLPG GS G G GP G G+PG G G+ G PG Sbjct: 172 KGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLK 231 Query: 380 GE--AGRPGSSGPSGDEGQPGEPGP------------PGEKGEAGDEGNPGPDGAPGERG 425 G G G G G+ GQ G PGP GEKG G G G G PG +G Sbjct: 232 GNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKG 291 Query: 426 --GPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGP 483 G G +G +G PG GPRGDPG G G G +G +G+ GDPG G IGPKG G+ G Sbjct: 292 ESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGH 351 Query: 484 PGSEGARGAP-----GPAGPPGDPGLMGERGEDGPAG------------------NGTEG 520 PG G P GP G PG PG GE G+ GP G G +G Sbjct: 352 PGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQG 411 Query: 521 FPGFPGYPGNRG-------APGINGTKGYPGLKGDEGEAGDPGD-----DNNDIAPRGVK 568 FPG PG PG G APG G G PGL G G G PG + P+G+K Sbjct: 412 FPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIK 471 Query: 569 GAKGYRGPEGPQG----------PPGHQGPPGP 591 G G G GP+G PG GPPGP Sbjct: 472 GKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGP 504 Score = 251 bits (641), Expect = 2e-66 Identities = 167/423 (39%), Positives = 191/423 (45%), Gaps = 95/423 (22%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG-- 314 G PG RGDPG G G PGL GE G GDPG G +GP KG+ G+RG G G Sbjct: 305 GFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGP------KGDPGNRGHPGPPGVL 358 Query: 315 ---PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPG--FDGIQGPPGPKGDPGAFGL 369 P KG G G G G G++G PG PG G PG G+ GPPGP+G PG GL Sbjct: 359 VTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGL 418 Query: 370 KGEKGEPG----ADGEAGRPGSSG------------------------PSGDEGQPGEPG 401 GE G PG A G+ G+PGS G P G +G+ G PG Sbjct: 419 PGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPG 478 Query: 402 PPGEKGEAGDEG----------NPGPDGAPGERGG------------------PGERGPR 433 G KGE G+EG PGP G PG +G PG GP Sbjct: 479 GRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPP 538 Query: 434 GTPGTRGPRGDPGEAGPQGD------------QGREGPVGVPGDPGEAGPIGPKGYRGDE 481 G PG G G PG G +GD +G +GP G PG PG G G G +GD Sbjct: 539 GLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDP 598 Query: 482 GPPG-----SEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGI 536 GPPG + G +G PGP GPPG G +G G P G G PG PG+PG RG G+ Sbjct: 599 GPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGL 658 Query: 537 NGTKG--------YPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGP 588 G KG YPG G G G PG P+G G G G +G G PG Sbjct: 659 KGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFP-GPQGAPGLSGSDGHKGRPGTPGTAEI 717 Query: 589 PGP 591 PGP Sbjct: 718 PGP 720 Score = 239 bits (610), Expect = 1e-62 Identities = 149/345 (43%), Positives = 166/345 (48%), Gaps = 55/345 (15%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GPPG G PG G+ G PGL G+ GE GDPG G G G G G KG G G G Sbjct: 1121 GPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLH 1180 Query: 317 GYKGEKGKRGIDGVD--GVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKG 374 G KG+KG +G G+ G G +G PGL G +G PG GI PPGP+G G G G G Sbjct: 1181 GLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGIS-PPGPRGKKGPPGPPGSSG 1239 Query: 375 EPGADGEAGR----------PGSSGPSGDEGQPGEPGPPGE-------KGEAGDEGNPGP 417 PG G GR PG GP G +G G PGPPG +GE GD G PGP Sbjct: 1240 PPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGP 1299 Query: 418 DGAPGERGGPGERG---PRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGP 474 G PG G PG +G G G +GP G PG GP G G G G+PG PG GP G Sbjct: 1300 PGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGL 1359 Query: 475 KGYRGDEGPP-------------------GSEGARGAPGPAGPPG-----DPGLMGERGE 510 G RG+ GPP G EGA G PG GP G +PGL G RG Sbjct: 1360 PGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGV 1419 Query: 511 DG-------PAGNGTEGFPGFPGYPGNRGAPGINGTKGY-PGLKG 547 DG P G G G+PG PG G G G KG+ PG G Sbjct: 1420 DGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGFGPGYLG 1464 Score = 60.8 bits (146), Expect = 6e-09 Identities = 44/118 (37%), Positives = 50/118 (42%), Gaps = 34/118 (28%) Query: 251 ECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310 +C G PG G G EG G PG+ G G PG G+ G+ G +G G Sbjct: 1374 DCPRIPGLPGAPGMRGPEGAMGLPGMRGPSG----PGCKGE------PGLDGRRGVDGVP 1423 Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFG 368 GS GP G KG+ GE GYPG P GPPGP GDPG G Sbjct: 1424 GSPGPPGRKGD------------TGEDGYPGGP------------GPPGPIGDPGPKG 1457 Score = 45.1 bits (105), Expect = 4e-04 Identities = 25/59 (42%), Positives = 31/59 (52%), Gaps = 17/59 (28%) Query: 256 RGP--PGLRGDPGFEGERG------KPGLPGEKGEAGDPGRP---------GDLGPVGY 297 RGP PG +G+PG +G RG PG PG KG+ G+ G P GD GP G+ Sbjct: 1400 RGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGF 1458 >gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] Length = 1745 Score = 298 bits (764), Expect = 1e-80 Identities = 173/377 (45%), Positives = 197/377 (52%), Gaps = 42/377 (11%) Query: 257 GPPGLRGDPGFEGERGKPGLPG------EKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310 GPPG G G EG++G G PG +KG+AG PG+PG GP G+ G G G++G + Sbjct: 1064 GPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRR 1123 Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCK------------GSPGFDGIQGP- 357 G G G KG+ G RG GV G G G PG PG K G+PG G QGP Sbjct: 1124 GPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPT 1183 Query: 358 --------PGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEA 409 PG G PGA G KGE+G+ G G G PG GP GD G+ G+ GP G G Sbjct: 1184 GSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPP 1243 Query: 410 GDEGNPGPDGAPGE---RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDP 466 G +G PG DGA G G PG+ GP G PG G G PGE G GD G GP G G+P Sbjct: 1244 GKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEP 1303 Query: 467 GEAGP---IGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-------N 516 G GP GP G+ G EG G +GA+G PGP GPPG G MG RG G G Sbjct: 1304 GAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIP 1363 Query: 517 GTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN--NDIAPRGVKGAKGYR 574 G G PG G PG G PG G G PGLKGD G G+ G I P G G KG + Sbjct: 1364 GPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQ 1423 Query: 575 GPEGPQGPPGHQGPPGP 591 G G QGPPG +G PGP Sbjct: 1424 GLPGVQGPPGPKGDPGP 1440 Score = 296 bits (758), Expect = 7e-80 Identities = 168/369 (45%), Positives = 199/369 (53%), Gaps = 34/369 (9%) Query: 255 ARGPPGLRGDPGFEGERG------KPGLPGEKGEAGDPGRPG---DLGPVGYQGMKGEKG 305 A+GPPG G PG+ G RG GL GEKGE G+ G PG D+G G QG G G Sbjct: 696 AQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPG 755 Query: 306 SRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPG 365 RGE G GPKG G+ G+ G G G KG++G PGLPG G PG G G PGP G G Sbjct: 756 PRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIG 815 Query: 366 AFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERG 425 G G+ G+PG +GE G PGS G G G G+PGP G+ G+ G G PG G PG +G Sbjct: 816 EKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQG 875 Query: 426 GPGERGPRGTPGTRGPRGDP------GEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRG 479 PG GP+G PG +G G P GE G QG G GP GV G G+ G +GP G RG Sbjct: 876 PPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERG 935 Query: 480 DEGPPGSEGARGAP---GPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGI 536 GPPG G +G P G G G+ G G G++GPA G GFPG G PG+ G G+ Sbjct: 936 PPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPA--GLRGFPGPKGGPGDPGPTGL 993 Query: 537 NGTKGYPGLKGDEGEAGD------------PGDDNND--IAPRGVKGAKGYRGPEGPQGP 582 G KG PG G G G+ PG ++ + P G KG++G RGP GP G Sbjct: 994 KGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGK 1053 Query: 583 PGHQGPPGP 591 G GP GP Sbjct: 1054 DGIPGPLGP 1062 Score = 292 bits (747), Expect = 1e-78 Identities = 170/379 (44%), Positives = 203/379 (53%), Gaps = 42/379 (11%) Query: 256 RGPPGL---RGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGY---QGMKGEKGSRGE 309 +GPPG +G PG +G+ G+PG PG++GE G G+ G GP G QG GE G GE Sbjct: 874 QGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGE 933 Query: 310 KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGL 369 +G GP G GE+G G++G +G KGE+G PG G +G G G GP G GDPG GL Sbjct: 934 RGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGL 993 Query: 370 KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPG---------PPGEKGEAGDEGNPGP--- 417 KG+KG PG G G PG GP G G G PG P G+KG G+ G PGP Sbjct: 994 KGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGK 1053 Query: 418 DGAPGERG--------GP----GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGD 465 DG PG G GP G++G G PG +G +GD G+AGP G G GP G PG Sbjct: 1054 DGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGP 1113 Query: 466 PG------EAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGT 518 PG GP G G +GD+G G G G PG G PG PG GE G+ G G +G Sbjct: 1114 PGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGA 1173 Query: 519 EGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIA-----PRGVKGAKGY 573 G G G G+ G PG+ G G PG G++GE GD GD A P+G G KG Sbjct: 1174 PGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGD 1233 Query: 574 RGPEGPQGPPGHQGPPGPD 592 GP G GPPG +GPPG D Sbjct: 1234 SGPSGAAGPPGKKGPPGED 1252 Score = 290 bits (741), Expect = 6e-78 Identities = 159/350 (45%), Positives = 191/350 (54%), Gaps = 15/350 (4%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G PG+ G PG +G G PG G GE G G PG GP GY G +G KG+ G +G +G K Sbjct: 668 GNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEK 727 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376 G KGE G G G G+KG+ G PG PG +G G +G +G G G+ G G GEKG+ Sbjct: 728 GEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKL 787 Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436 G G G PG GP G G PG GP GEKG++G G PG +G G G GERG G Sbjct: 788 GVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGAT 847 Query: 437 GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGA---P 493 G GP+GD G+ G G G +G G+ G PG GP GP G++G +G PG G RG Sbjct: 848 GQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQ 907 Query: 494 GPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTKGY------PGLK 546 G GPPG G++G +G+ G G G G PG PG PG +G PG+ G +G PG Sbjct: 908 GQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPL 967 Query: 547 GDEGEAG-----DPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G EG AG P D P G+KG KG GP G G PG +GP GP Sbjct: 968 GKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGP 1017 Score = 287 bits (735), Expect = 3e-77 Identities = 168/416 (40%), Positives = 197/416 (47%), Gaps = 83/416 (19%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GPPG G+ G G G PG PG G G G PG LGP+G +G G+ G G +G RGP Sbjct: 776 GPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPP 835 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPG---PKGDPGAFGLKGEK 373 G +GE+G+ G G G KG++G G PG G G G+QGPPG PKG PG G G Sbjct: 836 GSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRP 895 Query: 374 GEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPG----- 428 G PG GE G G +GP G G G G GE G G+ G PGP G PGE+G PG Sbjct: 896 GHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGRE 955 Query: 429 ----ERGP------------RGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPI 472 E GP RG PG +G GDPG G +GD+G GPVG G PGE GP+ Sbjct: 956 GAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPL 1015 Query: 473 GP---------------------KGYRGDEGPPGSEGARGAPGP---------------- 495 GP KG RG+ GPPG G G PGP Sbjct: 1016 GPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEE 1075 Query: 496 --------------------AGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAP 534 AGPPG PG+ G G GP G +G +G G PG G +G Sbjct: 1076 GDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDD 1135 Query: 535 GINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G+ G G G G +G G PG + ++ G G G GP GPQGP G +G PG Sbjct: 1136 GVRGFVGVIGPPGLQGLPGPPG-EKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPG 1190 Score = 286 bits (731), Expect = 9e-77 Identities = 174/364 (47%), Positives = 189/364 (51%), Gaps = 35/364 (9%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGD------PGRPGD------LGPVGYQGMKG 302 ARG PG G G G G PGLPGEKG+ GD PG PG+ GP G G G Sbjct: 537 ARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAG 596 Query: 303 EKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKG 362 E G RG G RG G G G GIDG G KG +G PG PG G G G QG PGP+ Sbjct: 597 EPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQ- 655 Query: 363 DPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPG 422 G G GEKG PG G G PGS GP G PG GP GEKG G G+ GP G PG Sbjct: 656 --GLIGTPGEKGPPGNPGIPGLPGSDGPL---GHPGHEGPTGEKGAQGPPGSAGPPGYPG 710 Query: 423 ERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDP---GEAGPIGPK---G 476 RG G G RG G +G +G+ G G +GD G +G G PG P GE GP GPK G Sbjct: 711 PRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAG 770 Query: 477 YRGDEGPPGSEGAR---GAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFPGYPG 529 G+EGPPGS G + G PG G PG PG G G GP G G G G PG G Sbjct: 771 QAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEG 830 Query: 530 NRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGP---EGPQGPPGHQ 586 RG PG G +G PG G G GD G D P G KG G +GP GP+GPPGHQ Sbjct: 831 ERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIP-GEKGLPGLQGPPGFPGPKGPPGHQ 889 Query: 587 GPPG 590 G G Sbjct: 890 GKDG 893 Score = 283 bits (725), Expect = 4e-76 Identities = 168/407 (41%), Positives = 201/407 (49%), Gaps = 74/407 (18%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GP GL G PG G G PGL GE+G G G G GP G G G+ G G G+RG Sbjct: 482 GPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLP 541 Query: 317 GYKGEKGKRGIDGVDGVKGE------MGYPGLPGCKGSPGFDGIQGPPGPKG---DPGAF 367 G G KG RG DG+ G+ GE G+ G PG G G G +GPPGP G +PG Sbjct: 542 GDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPR 601 Query: 368 GLKGEKGEPGADGE---AGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDG---AP 421 GL G +G PG G G G+ G G+ G PGEPGPPG++G G +G PGP G P Sbjct: 602 GLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTP 661 Query: 422 GERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK------ 475 GE+G PG G G PG+ GP G PG GP G++G +GP G G PG GP G K Sbjct: 662 GEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNR 721 Query: 476 ---------------------GYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPA 514 G +GD+G PG+ G RG GP GP G G GE G G A Sbjct: 722 GLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSA 781 Query: 515 GN----GTEGFPGFPGYPGNRGA---------------------PGINGTKGYPGLKGDE 549 G G G PG+PG PG +G+ PG+ G +G PG +G+ Sbjct: 782 GEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGER 841 Query: 550 ------GEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G+ G GD D AP G+ G KG G +GP G PG +GPPG Sbjct: 842 GQPGATGQPGPKGDVGQDGAP-GIPGEKGLPGLQGPPGFPGPKGPPG 887 Score = 282 bits (722), Expect = 1e-75 Identities = 162/368 (44%), Positives = 191/368 (51%), Gaps = 37/368 (10%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RGPPG G PG E+G PGL G +G G+ G PG LG G G++G G +G G GP Sbjct: 934 RGPPGPPGPPG---EQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGP 990 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375 G KG+KG G G +G GE G G G G PG G +GP GP G G+ G +G G Sbjct: 991 TGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGP 1050 Query: 376 PGADG------EAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGE 429 G DG G PG++GPSG+EG G+ G PG KG GD+G+ GP G PG RG G Sbjct: 1051 TGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGH 1110 Query: 430 RGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGA 489 GP G G +G RG PG G +GD G G VGV G PG G GP G +G+ G GS G Sbjct: 1111 PGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGP 1170 Query: 490 RGAPGPAGPP---------------GDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAP 534 GAPGP GP G PG +GE+GE G AG+ G PG PG PG +G Sbjct: 1171 HGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGD--PGPPGAPGIPGPKGDI 1228 Query: 535 GINGTKGYPGLKGDEGEAGDPGDDN-----------NDIAPRGVKGAKGYRGPEGPQGPP 583 G G G G G G+ G PG+D D+ P G G G G G +G P Sbjct: 1229 GEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDP 1288 Query: 584 GHQGPPGP 591 G G PGP Sbjct: 1289 GDVGGPGP 1296 Score = 282 bits (721), Expect = 1e-75 Identities = 162/353 (45%), Positives = 191/353 (54%), Gaps = 21/353 (5%) Query: 256 RGPPGLRGDPGFEG---ERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKG---EKGSRGE 309 RGP G G PG +G RG PGL G+KG+ G G G +GP G QG+ G EKG G+ Sbjct: 1105 RGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGD 1164 Query: 310 KGSRGPKGYKGEKGKRG---IDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366 GS GP G G +G +G +G G+ G +G PG G KG G G GPPG G PG Sbjct: 1165 VGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGP 1224 Query: 367 FGLKGEKGEPGADGEAGRPGSSGPSGDEGQ---------PGEPGPPGEKGEAGDEGNPGP 417 G GEKG+ G G AG PG GP G++G PG+ GPPG+ G +G +G+PG Sbjct: 1225 KGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGE 1284 Query: 418 DGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY 477 G PG+ GGPG G G PG GP G G +G G +GREG G G+PG GP G G Sbjct: 1285 KGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGP 1344 Query: 478 RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGIN 537 G GPPG G G G GP G+PGL+G G+ GP G G G PG G+ G G Sbjct: 1345 MGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPP--GPLGPSGLPGLKGDTGPKGEK 1402 Query: 538 GTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G G GL G GEAG+ GD +G G KG GP GP G GH GPPG Sbjct: 1403 GHIGLIGLIGPPGEAGEKGDQGLP-GVQGPPGPKGDPGPPGPIGSLGHPGPPG 1454 Score = 280 bits (715), Expect = 6e-75 Identities = 162/370 (43%), Positives = 187/370 (50%), Gaps = 39/370 (10%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GP G GDPG G +G G PG G G PG G LGP G G+ G+ GS G G G K Sbjct: 980 GPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKK 1039 Query: 317 GYKGEKGKRGIDGVDGV---------------------KGEMGYPGLPGCKGS------P 349 G +GE+G G G DG+ KG++G PG G KG P Sbjct: 1040 GSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPP 1099 Query: 350 GFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE---PGPPGEK 406 G GI+GP G G PGA G +G +G PG G+ G G G G G PG PGPPGEK Sbjct: 1100 GQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEK 1159 Query: 407 GEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDP 466 GE GD G+ GP GAPG RG G G GTPG G G PG G +G++G G G PG P Sbjct: 1160 GEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAP 1219 Query: 467 GEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN----GTEGFP 522 G GP G G +GD GP GA G PG GPPG+ G G G G G+ G G Sbjct: 1220 GIPGPKGDIGEKGDSGP---SGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVS 1276 Query: 523 GFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPG--DDNNDIAPRGVKGAKGYRGPEGPQ 580 G G PG +G PG G G PG G+ G G PG + + G +G KG +G GP Sbjct: 1277 GIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPD 1336 Query: 581 GPPGHQGPPG 590 GPPG GP G Sbjct: 1337 GPPGRTGPMG 1346 Score = 274 bits (700), Expect = 4e-73 Identities = 173/421 (41%), Positives = 198/421 (47%), Gaps = 86/421 (20%) Query: 256 RGPPGLRGDPGFEGERGKPG------------LPGEKGEAGDP------GRPGDLGPVGY 297 +G PGL G G +GE G PG PG KG GDP G G GPVG Sbjct: 946 QGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGA 1005 Query: 298 QGMKGEKGS---------RGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGS 348 G GE+G G+ GS GP G G+KG RG G G G+ G PG G G Sbjct: 1006 NGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGP 1065 Query: 349 PGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE--------- 399 PG G G G KGD GA G KG KG+ G G G+PG GP+G G PG Sbjct: 1066 PGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGP 1125 Query: 400 ---------------------------PGPPGEKGEAGDEGNPGPDGAPGERGGPGERGP 432 PGPPGEKGE GD G+ GP GAPG RG G G Sbjct: 1126 PGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGS 1185 Query: 433 RGTP------------GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480 GTP G +G RGD G+ GP G G GP G G+ G++GP G G G Sbjct: 1186 EGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGK 1245 Query: 481 EGPPGSEGARGA------PGPAGPPGDPGLMGERGEDGPAGN----GTEGFPGFPGYPGN 530 +GPPG +GA+G+ PG GPPGDPG+ G G G G+ G G PG G PG Sbjct: 1246 KGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGA 1305 Query: 531 RGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G PG G G+ G +G EGE G G+ D P G G G RGP G GP G +G PG Sbjct: 1306 PGPPGKRGPSGHMGREGREGEKGAKGEPGPD-GPPGRTGPMGARGPPGRVGPEGLRGIPG 1364 Query: 591 P 591 P Sbjct: 1365 P 1365 Score = 271 bits (694), Expect = 2e-72 Identities = 170/414 (41%), Positives = 199/414 (48%), Gaps = 73/414 (17%) Query: 250 FECQPARGPPGLRGDPG-------FEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKG 302 F+ P G G +G+P FEG G PG G G +G PG PG G G G G Sbjct: 366 FQIFPGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAG 425 Query: 303 EKGSRGEKGSRGPKG-------------YKGE--------------------KGKRGIDG 329 G G G RGP G +KG KG G G Sbjct: 426 LPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVG 485 Query: 330 VDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSG 389 + G G +G PG PG KG G +G QGP G +G G G G+ G PGADG G PG +G Sbjct: 486 LTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTG 545 Query: 390 PSGDEGQPGEPGPPGEKGEAGDEGN---PGPDGAPGERGGPGERGPRGTPGTRGPRGDPG 446 P GD G G PG PGEKG+ GD G+ PGP G GERG G GP G G GPRG G Sbjct: 546 PKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLG 605 Query: 447 EAGPQGDQGREGPVGVPG---------DPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAG 497 G G GR G G+ G PGE GP G +G G +G PG +G G PG G Sbjct: 606 PRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKG 665 Query: 498 PPGDPGLMGERGEDGPAGN----------GTEGFPGF---PGYPGNRGAPGINGTKGYPG 544 PPG+PG+ G G DGP G+ G +G PG PGYPG RG G +G +G G Sbjct: 666 PPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQG 725 Query: 545 LKGDEGEAGDPG--DDNNDIAPRGVKGAKGYRGPEGPQGP------PGHQGPPG 590 KG++GE G PG D +G GA G RG +GP+GP G +GPPG Sbjct: 726 EKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPG 779 Score = 266 bits (681), Expect = 6e-71 Identities = 165/410 (40%), Positives = 191/410 (46%), Gaps = 81/410 (19%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPG----------------------------- 287 GPPG GDPG G G PG+PG G G PG Sbjct: 410 GPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAV 469 Query: 288 -------------------RPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGID 328 RPG +G G+ G+KGE+G+ G +G RG +G G G+ G Sbjct: 470 LQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKM 529 Query: 329 GVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSS 388 G G G G PG G KG GFDG+ G PG KG G FG G+ G PG DGE G G Sbjct: 530 GRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPP 589 Query: 389 GPSGDEGQPGEPGPPGEKGEAGDEGNPGP---DGAPGERGG---PGERGPRGTPGTRGPR 442 GP+G G+PG G G +G G G PG DGAPG +G PGE GP G G G + Sbjct: 590 GPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQ 649 Query: 443 GDPGEAGPQGDQGREGPVG---VPGDPGEAGPIG------PKGYRGDEGPPGSEGARGAP 493 G PG G G G +GP G +PG PG GP+G P G +G +GPPGS G G P Sbjct: 650 GLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYP 709 Query: 494 GPAGPPGDPGLMGERGEDGPAGNGTEGFPGF------------PGYPGNRGAPGINGTKG 541 GP G G G G +GE G G +GFPGF PG PG RG G G KG Sbjct: 710 GPRGVKGTSGNRGLQGEKGE--KGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKG 767 Query: 542 YPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G G+EG G G+ GV G GY G GP+G G GP GP Sbjct: 768 QAGQAGEEGPPGSAGEKGK----LGVPGLPGYPGRPGPKGSIGFPGPLGP 813 Score = 263 bits (671), Expect = 8e-70 Identities = 151/326 (46%), Positives = 168/326 (51%), Gaps = 13/326 (3%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 +GP G G PG G G+PG GEKGE GD G PG P G G+ G KG GEKG GP Sbjct: 1180 QGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPG---PPGAPGIPGPKGDIGEKGDSGP 1236 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGC---KGSPGFDGIQGPPGPKGDPGAFGLKGE 372 G G GK+G G DG KG +G GLPG G PG GI G PG KGDPG G G Sbjct: 1237 SGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGP 1296 Query: 373 KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGP 432 G G G G PG GPSG G+ G G G KGE G +G PG G G RG PG GP Sbjct: 1297 PGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGP 1356 Query: 433 RGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGA 492 G G GP G+PG G G G GP+G G PG G GPKG ++G G G G Sbjct: 1357 EGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKG---EKGHIGLIGLIGP 1413 Query: 493 PGPAGPPGDPGLMGERGEDGPAGN----GTEGFPGFPGYPGNRGAPGINGTKGYPGLKGD 548 PG AG GD GL G +G GP G+ G G G PG PG G G G+KG PG G Sbjct: 1414 PGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGP 1473 Query: 549 EGEAGDPGDDNNDIAPRGVKGAKGYR 574 G+ G G AP + G + R Sbjct: 1474 RGDTGPAGPPGPPGAPAELHGLRRRR 1499 Score = 236 bits (602), Expect = 8e-62 Identities = 134/305 (43%), Positives = 154/305 (50%), Gaps = 23/305 (7%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314 A G G RGD G G G PG+PG KG+ G+ G G G G G KG G G KGS G Sbjct: 1200 AVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVG 1259 Query: 315 PKGYKGE---KGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKG 371 P G G+ G G+ G+DG GE G PG G G PG G G PGP G G G G Sbjct: 1260 PTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMG 1319 Query: 372 EKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERG 431 +G G G G PG GP G G G GPPG G G G PGP G PG G PG+ G Sbjct: 1320 REGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMG 1379 Query: 432 PRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARG 491 P G G G G G+ GP+G++G G +G+ G PGEAG +GD+G P G +G Sbjct: 1380 PPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGE------KGDQGLP---GVQG 1430 Query: 492 APGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGE 551 PGP G PG PG +G G GP PG G G G G+ G G +GD G Sbjct: 1431 PPGPKGDPGPPGPIGSLGHPGP-----------PGVAGPLGQKGSKGSPGSMGPRGDTGP 1479 Query: 552 AGDPG 556 AG PG Sbjct: 1480 AGPPG 1484 Score = 144 bits (364), Expect = 3e-34 Identities = 84/196 (42%), Positives = 94/196 (47%), Gaps = 30/196 (15%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKG------------ 302 A GPPG RG G G G+ G G KGE G G PG GP+G +G G Sbjct: 1305 APGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPG 1364 Query: 303 ---EKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGY---------PGLPGCKGSPG 350 E G G G GP G G G G+ G G KGE G+ PG G KG G Sbjct: 1365 PVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQG 1424 Query: 351 FDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAG 410 G+QGPPGPKGDPG G G G PG PG +GP G +G G PG G +G+ G Sbjct: 1425 LPGVQGPPGPKGDPGPPGPIGSLGHPGP------PGVAGPLGQKGSKGSPGSMGPRGDTG 1478 Query: 411 DEGNPGPDGAPGERGG 426 G PGP GAP E G Sbjct: 1479 PAGPPGPPGAPAELHG 1494 Score = 103 bits (257), Expect = 8e-22 Identities = 78/213 (36%), Positives = 90/213 (42%), Gaps = 49/213 (23%) Query: 408 EAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPG 467 E GD+ GPD E + G +G +G+P A + Q EGP G PG G Sbjct: 344 EEGDDSTMGPDFRAAEYPSRTQFQIFPGAGEKGAKGEP--AVIEKGQQFEGPPGAPGPQG 401 Query: 468 EAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGP--------AGNGTE 519 GP GP G PPG G G PGPAG PG PG+ G RG G AG + Sbjct: 402 VVGPSGPPG------PPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFK 455 Query: 520 GFP--------------------GFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN 559 G P G PG G G PG G G+PGLKG+EG G G Sbjct: 456 GPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQG--- 512 Query: 560 NDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592 PRG++ GP GP G G G PG D Sbjct: 513 ----PRGLQ------GPHGPPGRVGKMGRPGAD 535 Score = 78.6 bits (192), Expect = 3e-14 Identities = 50/142 (35%), Positives = 64/142 (45%), Gaps = 25/142 (17%) Query: 473 GPKGYRGD----------EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFP 522 G KG +G+ EGPPG+ G +G GP+GPPG PG G+ G GPAG P Sbjct: 373 GEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAG-----LP 427 Query: 523 GFPGYPGNRGAPGI---------NGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573 G PG G RG PG G+ P + + +A ++ +G G G Sbjct: 428 GIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQA-QAVLQQTQLSMKGPPGPVGL 486 Query: 574 RGPEGPQGPPGHQGPPGPDECE 595 G GP G PGH G G + E Sbjct: 487 TGRPGPVGLPGHPGLKGEEGAE 508 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 297 bits (761), Expect = 3e-80 Identities = 176/376 (46%), Positives = 202/376 (53%), Gaps = 40/376 (10%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GPPG +G+PG G+ G G PG KG GD G PG P G +G G G G+ GS G Sbjct: 1003 GPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG---PQGVEGPPGPSGVPGQPGSPGLP 1059 Query: 317 GYKGEKGKRGID-----GVDGVKGEMG---YPGLPGCKGS---PGFDGIQGPPGPKGDPG 365 G KG+KG GI G+ G KGE G YPG PG KGS PG G+ G PG KG PG Sbjct: 1060 GQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPG 1119 Query: 366 AFGLKGEKGEPGADGEAGRPGSSG------PSGDEGQPGEPGPPGEKGEAGDEGNPGPDG 419 G G G PG G +G PG+ G P G G PG+PGPPGEKG+ G +G PGP G Sbjct: 1120 LPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG 1179 Query: 420 APGERGGPG--ERGPRGTPGTRGPRGD---------PGEAGPQGDQGREGPVGV---PGD 465 GE G PG GP G PG G +GD PG GP+G+ G G GV PG Sbjct: 1180 QKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGP 1239 Query: 466 PGEAGPI--GPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPG 523 PG GP GPKG G +GPPG G +G PGP GPPG PG G +GE G G G PG Sbjct: 1240 PGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQ--PGLPG 1297 Query: 524 FPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN--NDIAPRGVKGAKGYRGPEGPQG 581 PG G++G PG+ G G PGL G +G+ G PG P GV G+ G G G G Sbjct: 1298 LPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIG 1357 Query: 582 PPGHQGPPGPDECEIL 597 PPG G PGP I+ Sbjct: 1358 PPGPPGLPGPSGQSII 1373 Score = 294 bits (753), Expect = 3e-79 Identities = 164/344 (47%), Positives = 190/344 (55%), Gaps = 25/344 (7%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312 Q GPPG G P G+ G PGLPG+KG+ GDPG + +G G+ G KG G G Sbjct: 1038 QGVEGPPGPSGVP---GQPGSPGLPGQKGDKGDPG----ISSIGLPGLPGPKGEPGLPGY 1090 Query: 313 RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372 G G KG G G+ G+ G G G PGLPG G+P GPPGPKG G G G Sbjct: 1091 PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTP------GPPGPKGISGPPGNPGL 1144 Query: 373 KGEPGADGEAGRPGSSGPSGDEGQPGE---PGPPGEKGEAGDE--GNPGPDGAPGERGGP 427 GEPG G G PG GP G++G+PG+ PGP G+KGE G GNPGP G PG G Sbjct: 1145 PGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQK 1204 Query: 428 GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487 G+ G G PG G G GE G G G +GP G PG PG A GPKG G +GPPG Sbjct: 1205 GDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALE-GPKGNPGPQGPPGRP 1263 Query: 488 GARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKG 547 G +G PGP GPPG PG G +GE G G G PG PG G++G PG+ G G PGL G Sbjct: 1264 GFQGLPGPEGPPGLPGNGGIKGEKG--NPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNG 1321 Query: 548 DEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 +G+ G PG G+KG G G GP+G PG GPPGP Sbjct: 1322 MKGDPGLPGVPGFP----GMKGPSGVPGSAGPEGEPGLIGPPGP 1361 Score = 290 bits (743), Expect = 4e-78 Identities = 177/409 (43%), Positives = 204/409 (49%), Gaps = 77/409 (18%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMK------------- 301 A GP G G PG G+ G G PG KGE G G PG GP+G G Sbjct: 870 APGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQG 929 Query: 302 --------GEKGSRGEKGSRGPK--------GYKGEKGKRGIDGVDGVKGEMGYPGLPGC 345 GEKGS+GE G GP G KGEKG+ G+ G+ GV G GY GLPG Sbjct: 930 QPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD 989 Query: 346 KGSPGFD---GIQGPPGPKGDP---------GAFGLKGEKGEPGADGEAGRPGSSGPSGD 393 G PG G+ GPPGPKG+P G GLKG G+ G G G G GPSG Sbjct: 990 PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049 Query: 394 EGQPGEPGPPGEKGEAGD--------EGNPGPDGAPGERGGPGERGPRGT---------P 436 GQPG PG PG+KG+ GD G PGP G PG G PG G +G+ P Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLP 1109 Query: 437 GTRGPRGD------PGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE--- 487 GT G +G PG GP G +G GP G PG PGE GP+G G+ G GPPG + Sbjct: 1110 GTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKP 1169 Query: 488 GARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFPGYPGNRGAPGINGTKGYP 543 G G PGPAG G+PG G G GP G +G +G G PG PGN G PG G G+ Sbjct: 1170 GQDGIPGPAGQKGEPGQPG-FGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFH 1228 Query: 544 GLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592 G G +G G PG ++G KG GP+GP G PG QG PGP+ Sbjct: 1229 GFPGVQGPPGPPGSPG-----PALEGPKGNPGPQGPPGRPGFQGLPGPE 1272 Score = 286 bits (733), Expect = 5e-77 Identities = 167/351 (47%), Positives = 185/351 (52%), Gaps = 28/351 (7%) Query: 257 GPPGLR--GDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314 GPPGL G PG G G PG PG G G PG PG G G+ G KGE G G G G Sbjct: 849 GPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPG 908 Query: 315 PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGS---PGFDGIQGPPGPKGDPGAFGLKG 371 P G G G G+ G DG++G+ G PG G KGS P G+ GPPGP DP G KG Sbjct: 909 PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEP---GLPGPPGPM-DPNLLGSKG 964 Query: 372 EKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERG 431 EKGEPG G PG SGP G +G PG+PG PG G+ G G PGP G PG G PG G Sbjct: 965 EKGEPGL---PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIG 1021 Query: 432 PRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE-----GPPGS 486 P PG +G GD G GPQG +G GP GVPG PG G G KG +GD G PG Sbjct: 1022 P---PGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGL 1078 Query: 487 EGARGAPGPAGPPGDPGLMGERGEDG-------PAGNGTEGFPGFPGYPGNRGAPGINGT 539 G +G PG G PG+PG+ G G+ G P G G PGFPG PG G GI+G Sbjct: 1079 PGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGP 1138 Query: 540 KGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G PGL G+ G G G P G KG G G GP G G G PG Sbjct: 1139 PGNPGLPGEPGPVGGGGHPGQP-GPPGEKGKPGQDGIPGPAGQKGEPGQPG 1188 Score = 281 bits (720), Expect = 2e-75 Identities = 167/374 (44%), Positives = 193/374 (51%), Gaps = 46/374 (12%) Query: 252 CQPARGPPGLRGDPGFEGERGKPGLPGEKGEA-------------GDPGRPGDLGPVGYQ 298 C+P GPPG G PG +G +G+ G+ G+KG+ G PG PG GP G Sbjct: 451 CEP--GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSL 508 Query: 299 GMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMG-------------------Y 339 G G+KG +G+ G+ GPKG G G G G G KGE G Sbjct: 509 GFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGA 568 Query: 340 PGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE 399 PGLPG G+PG DG+ G PGPKG+PG KGE+G PG G G PG+ GP G G G Sbjct: 569 PGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GP 627 Query: 400 PGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPR-GTPGTRGPRGDPGEAGPQGDQGREG 458 PGP GEKG G GNPG G PG +G PG+ + G PG G G G+ G GD G G Sbjct: 628 PGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPG 687 Query: 459 PVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NG 517 G+PG PG G G G G GPPG +G G PGP G PG PG +G G GP G G Sbjct: 688 QPGLPGIPGSKGEPGIPGI-GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746 Query: 518 TEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPE 577 +G PGF PG G PG+ G KG G KGD G G PG P G G G GP+ Sbjct: 747 PKGEPGF-ALPGPPGPPGLPGFKGALGPKGDRGFPGPPG-------PPGRTGLDGLPGPK 798 Query: 578 GPQGPPGHQGPPGP 591 G GP G GP GP Sbjct: 799 GDVGPNGQPGPMGP 812 Score = 278 bits (711), Expect = 2e-74 Identities = 167/385 (43%), Positives = 195/385 (50%), Gaps = 50/385 (12%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RG PG+ G PG G G PGLPG+ G +G PG G++G +G G G G G G G Sbjct: 862 RGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGL 921 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLP-----------GCKGSPGFDGIQGPPGPKGDP 364 KG G +G+ G+ G G KG G PGLP G KG G G+ G PG G Sbjct: 922 KGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPK 981 Query: 365 GAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEP---GPPGEKGEAGD---------E 412 G GL G+ G+PG G+ G PG GP G+ G PG+P GPPG KG GD E Sbjct: 982 GYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVE 1041 Query: 413 GNPGPDGAPGERGGPGERGPR-----------GTPGTRGPRGDPGEAGPQGDQGREGPVG 461 G PGP G PG+ G PG G + G PG GP+G+PG G G+ G +G VG Sbjct: 1042 GPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVG 1101 Query: 462 VPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEG 520 PG PG G G KG G G PG+ G G G +GPPG+PGL GE G G G+ G G Sbjct: 1102 DPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPG 1161 Query: 521 FPGFPGYPGNRGAPGINGTK--------------GYPGLKGDEGEAGDPGDDNNDIAPRG 566 PG G PG G PG G K G PGL G +G+ G PG N P G Sbjct: 1162 PPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLP-G 1220 Query: 567 VKGAKGYRGPEGPQGPPGHQGPPGP 591 KG G+ G G QGPPG G PGP Sbjct: 1221 PKGEPGFHGFPGVQGPPGPPGSPGP 1245 Score = 278 bits (710), Expect = 2e-74 Identities = 163/379 (43%), Positives = 195/379 (51%), Gaps = 47/379 (12%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPG--RPGDLGPVGYQGMKGEKGSRGE----- 309 G GL GDPG G+ G PG+PG KGE G PG PG GP G+ G+ G G+ G Sbjct: 675 GDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIG 734 Query: 310 -KGSRGPKGYKGEKGKRGI--------------DGVDGVKGEMGYPGLPGCKGSPGFDGI 354 +G GP G+ G KG+ G G G KG+ G+PG PG G G DG+ Sbjct: 735 LEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGL 794 Query: 355 QGP---------PGPKGDPG--AFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPG-- 401 GP PGP G PG G++G G PG G G+PG G G++G PG PG Sbjct: 795 PGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLD 854 Query: 402 ---PPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREG 458 PPGE+G G G PGP G PG G PG+ G G PGT+G G G GP G G G Sbjct: 855 VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPG 914 Query: 459 PVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG--- 515 GVPG G+ G G G G G GS+G G PGP GP DP L+G +GE G G Sbjct: 915 RSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPM-DPNLLGSKGEKGEPGLPG 973 Query: 516 -NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGA---K 571 G G G+ G PG+ G PG++G G PG G +G G PG I P G+KG Sbjct: 974 IPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGL-IGPPGLKGTIGDM 1032 Query: 572 GYRGPEGPQGPPGHQGPPG 590 G+ GP+G +GPPG G PG Sbjct: 1033 GFPGPQGVEGPPGPSGVPG 1051 Score = 278 bits (710), Expect = 2e-74 Identities = 166/357 (46%), Positives = 186/357 (52%), Gaps = 24/357 (6%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G PGL G PG G +G+PGLPG G G PG G GP G G+ GE G G G G Sbjct: 1101 GDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQP 1160 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD------PGAFGLK 370 G GEKGK G DG+ G G+ G PG PG G+PG G+ G G KGD PG GL Sbjct: 1161 GPPGEKGKPGQDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGLPGIPGNPGLP 1219 Query: 371 GEKGEPGADGEAGRPGSSGPSGD-----EGQPGEPGPPGEKGEAGDEGNPGPDGAPGERG 425 G KGEPG G G G GP G EG G PGP G G G +G PGP+G PG G Sbjct: 1220 GPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPG 1279 Query: 426 GPGERGPRGTPGTRGP------RGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRG 479 G +G +G PG G +GD G G QG+ GR G G+ GDPG G G G +G Sbjct: 1280 NGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKG 1339 Query: 480 DEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGT 539 G PGS G G PG GPPG PGL G G+ G G PG PG PG +G PG G Sbjct: 1340 PSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQ-SIIIKGDAGPPGIPGQPGLKGLPGPQGP 1398 Query: 540 KGYP---GLKGDEGEAGDPGDD--NNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 +G P G GD G G PG D G+ G G RG +GP GP G QGPPGP Sbjct: 1399 QGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGP 1455 Score = 275 bits (704), Expect = 1e-73 Identities = 166/367 (45%), Positives = 188/367 (51%), Gaps = 52/367 (14%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPG---DLGPVG------YQGMKGEKGSR 307 G PG +G PG G G PG PG KG +G PG PG + GPVG G GEKG Sbjct: 1110 GTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKP 1169 Query: 308 GEKGSRGPKGYKGEKGKRG--------IDGVDGVKGEMGYPGLPGCKGSPG--------- 350 G+ G GP G KGE G+ G + G+ G KG+ G PG+PG G PG Sbjct: 1170 GQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHG 1229 Query: 351 FDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAG 410 F G+QGPPGP G PG L+G KG PG G GRPG G G EG PG PG G KGE G Sbjct: 1230 FPGVQGPPGPPGSPGP-ALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKG 1288 Query: 411 DEGNPGPDGAPG---ERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPG 467 + G PG G PG ++G PG +G G PG G +GDPG G G G +GP GVPG Sbjct: 1289 NPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGS-- 1346 Query: 468 EAGPIGPKGYRGDEGPPGSEGARGAP----GPAGPPGDPGLMGERGEDGPAGNGTEGFPG 523 AGP G G G GPPG G G G AGPPG PG G +G GP G +G PG Sbjct: 1347 -AGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGP--QGPQGLPG 1403 Query: 524 FPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPP 583 G PG+ G G+ G G G KGD G G PG +G GP GP G Sbjct: 1404 PTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPG-------------TRGLDGPPGPDGLQ 1450 Query: 584 GHQGPPG 590 G GPPG Sbjct: 1451 GPPGPPG 1457 Score = 274 bits (701), Expect = 3e-73 Identities = 161/375 (42%), Positives = 189/375 (50%), Gaps = 43/375 (11%) Query: 255 ARGPPGLR---GDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGM----------- 300 A GP G R G PG G G GLPG KG+ G G+PG +GP G G+ Sbjct: 770 ALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI 829 Query: 301 ------KGEKGSRGEKGSRGPKGY-----KGEKGKRGIDGVDGVKGEMGYPGLPGCKGSP 349 G G GEKG GP G GE+G GI G G G G PGLPG G+ Sbjct: 830 PGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889 Query: 350 GFDGIQ---------GPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEP 400 GF G + GPPGP G PG G+ G KG+ G G+ G PG +G G +G+PG P Sbjct: 890 GFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLP 949 Query: 401 GPPGEK-----GEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQG 455 GPPG G G++G PG G PG G G +G G PG G G PG GP G +G Sbjct: 950 GPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKG 1009 Query: 456 REGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG 515 G+PG PG GP G KG GD G PG +G G PGP+G PG PG G G+ G G Sbjct: 1010 NP---GLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG 1066 Query: 516 NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRG 575 + G PG PG +G PG+ G G PG+KG G+ G PG A +G G G+ G Sbjct: 1067 DPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGA-KGQPGLPGFPG 1125 Query: 576 PEGPQGPPGHQGPPG 590 GP GP G GPPG Sbjct: 1126 TPGPPGPKGISGPPG 1140 Score = 271 bits (694), Expect = 2e-72 Identities = 170/409 (41%), Positives = 194/409 (47%), Gaps = 75/409 (18%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RG PGL G PG G G G PG +G+ GD G PG GP G +G G G G G G Sbjct: 50 RGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGM 109 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFG------- 368 G+ G G +GI G +G KGE G+PG SPGF G+QGPPGP G PG G Sbjct: 110 PGHDGAPGPQGIPGCNGTKGERGFPG------SPGFPGLQGPPGPPGIPGMKGEPGSIIM 163 Query: 369 --LKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPP----------------------- 403 L G KG PG G G G GP+G G G PGPP Sbjct: 164 SSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQ 223 Query: 404 ---GEKGEAGDEGNPGPDG-------------APGERGGPGERGPRGTPGTRGPRGDP-G 446 GEKGE G +G PGP G G++G PG+RGP G PG RGP G P G Sbjct: 224 GPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGG 283 Query: 447 EAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD---EGPPGSEGARGAPGPAGPPGDPG 503 E G +G+QG G G PG GE G G G GD G PG +G +G G GPPG PG Sbjct: 284 EKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPG 343 Query: 504 L----------MGERGEDG----PAGNGTEGFPGFPGYPGNRGAPG--INGTKGYPGLKG 547 L +GE+G G P G GFPG G PG G PG + G G PG G Sbjct: 344 LVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPG 403 Query: 548 DEGEAGDPGDDNNDI-APRGVKGAKGYRGPEGPQGPPGHQGPPGPDECE 595 + G+ GD G I P G+ G G G GP GP G PP + CE Sbjct: 404 ERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICE 452 Score = 270 bits (689), Expect = 7e-72 Identities = 165/367 (44%), Positives = 187/367 (50%), Gaps = 31/367 (8%) Query: 254 PARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGR----------PGDLGPVGYQGMKGE 303 P GPPG G+ G +G G PG PG G GDPG+ PG+ G G G+ G+ Sbjct: 623 PGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGD 682 Query: 304 KGSRGEKGSRGPKGYKGEKGKRGI--DGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361 G G+ G G G KGE G GI G G KG G PG PG G+PG G++GPPGP Sbjct: 683 PGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPP 742 Query: 362 GDPGAFGLKG--EKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGE---------KGEAG 410 G PG G G G PG G G G+ GP GD G PG PGPPG KG+ G Sbjct: 743 GFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVG 802 Query: 411 DEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVG--VPGDPGE 468 G PGP G PG G G +GP G PG GP G PG G G++G GP G VPG PGE Sbjct: 803 PNGQPGPMGPPG-LPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGE 861 Query: 469 AGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGF 524 G G G G GPPGS G G G +G PG G MG G GP G G G PG Sbjct: 862 RGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGL 921 Query: 525 PGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGD-DNNDIAPRGVKGAKGYRGPEGPQGPP 583 G G +G PG+ G G G KG+ G G PG D N + +G KG G G G GP Sbjct: 922 KGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPK 981 Query: 584 GHQGPPG 590 G+QG PG Sbjct: 982 GYQGLPG 988 Score = 268 bits (686), Expect = 1e-71 Identities = 168/395 (42%), Positives = 196/395 (49%), Gaps = 55/395 (13%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG-- 314 G PGL G PG G+ G PGLPG KGE G G+ GP G G+ G G+ G G G Sbjct: 567 GAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFG 626 Query: 315 PKGYKGEKGKRGI------DGVDGVKGEMGY----PGLPGCKGSPGFDG---IQGPPGPK 361 P G GEKG +G+ G+ G KG+ G PG PG G+PG DG + G PG Sbjct: 627 PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP 686 Query: 362 GDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAP 421 G PG G+ G KGEPG G G PG GP G G PG PG PG G G EG PGP G P Sbjct: 687 GQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFP 745 Query: 422 GERGGPG-----ERGPRGTPGTRG---PRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIG 473 G +G PG GP G PG +G P+GD G GP G GR G G+PG G+ GP G Sbjct: 746 GPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNG 805 Query: 474 PKGYRGDEGPPG-----SEGARGAPGPAGPPGDPGLMGERGEDGPAG---------NGTE 519 G G G PG G G PGP G PG G+ GE+G+ GP G G+ Sbjct: 806 QPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSP 865 Query: 520 GFPGFPGY---PGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN--------------NDI 562 G PG PG PG+ G PG G G+PG KG+ G G PG D Sbjct: 866 GIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDD 925 Query: 563 APRGVKGAKGYRGPEGPQGPPGHQGPPGPDECEIL 597 +G G G G +G +G PG GPPGP + +L Sbjct: 926 GLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960 Score = 268 bits (685), Expect = 2e-71 Identities = 168/384 (43%), Positives = 194/384 (50%), Gaps = 52/384 (13%) Query: 257 GPPGLRGDPGFEGERGK------------PGLPGEKGEAGDPGRPGDLGPVGYQGMKGEK 304 GPPG G PG +GE+G+ PG PG G G G PGD+ + + GMKG+K Sbjct: 503 GPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDI--LTFPGMKGDK 560 Query: 305 GSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMG---YPGLPGCKGSPGFDGIQGPPGPK 361 G G G+ G G G G+ G+ G+ G KGE G + G G G+PG G+ G GP Sbjct: 561 GELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPM 620 Query: 362 GDP--GAFGLKGEKGEPGADGEAGRPGSSGPSGDEG----QPGEPGPPGEKGEAGDEGNP 415 G P G G GEKG G G G+PG GP GD G QPG+PG PG G GD G P Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLP 680 Query: 416 GPDGAPGER-----------------GGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREG 458 G G PG+ G PG GP+G PG GP G PG G G +G G Sbjct: 681 GDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPG 740 Query: 459 PVGVPGDPGE-----AGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGD---PGLMGERGE 510 P G PG GE GP GP G G +G G +G RG PGP GPPG GL G +G+ Sbjct: 741 PPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGD 800 Query: 511 DGPAGN-GTEGFPGFP--GYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDI-APRG 566 GP G G G PG P G G G PGI G G PGL G GE GDPG D+ P G Sbjct: 801 VGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPG 860 Query: 567 VKGAKGYRGPEGPQGPPGHQGPPG 590 +G+ G G GP GPPG G PG Sbjct: 861 ERGSPGIPGAPGPIGPPGSPGLPG 884 Score = 266 bits (679), Expect = 1e-70 Identities = 178/436 (40%), Positives = 208/436 (47%), Gaps = 108/436 (24%) Query: 257 GPPGLRGDPG---FEGERGKPGLPGEKGEAGDPGRPGDLGPVG--YQGMKGEKGSRGEKG 311 GPPG++G PG G G PG PG G G PG PG G +G +QG KGEKG +G +G Sbjct: 177 GPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQG 236 Query: 312 SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP----KGDPGAF 367 GP G E+ KR ID V+ + G GLPG +G PG GI+GPPGP KG+ G Sbjct: 237 PPGPPGQISEQ-KRPID----VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQ 291 Query: 368 GLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA------- 420 G G++G+PG DGE G+PG G GD G PGEPG GEKG+ GD G PGP G Sbjct: 292 GEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGT 351 Query: 421 ------------------PGERGGPGERGPRGTPGTRG--------PRGDPGEAGPQGDQ 454 GERG PG +GP G PG G P G PGE G +GD+ Sbjct: 352 GITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDE 411 Query: 455 GREG-----PVGVPGDPGEAGPIGPKGYRGDEGPPGSEGAR-GAPGPAGPPGDPGLMGER 508 G G P G+ G PG G GP G G PP E G PGP G PGD GL GE+ Sbjct: 412 GPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQ 471 Query: 509 GEDGPAGN--------------------------GTEGFP---------------GFPGY 527 G G G+ G+ GFP G PG Sbjct: 472 GVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI 531 Query: 528 PGNRGAPGINGTKG-------YPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQ 580 PG GAPG G+KG +PG+KGD+GE G PG P G G G G GP+ Sbjct: 532 PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLP-GTPGQDGLPGLPGPK 590 Query: 581 GPP------GHQGPPG 590 G P G +GPPG Sbjct: 591 GEPGGITFKGERGPPG 606 Score = 265 bits (676), Expect = 2e-70 Identities = 165/364 (45%), Positives = 186/364 (51%), Gaps = 39/364 (10%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG--S 312 A G PGL G P G+ G PGLPG KGE G G+ GP G G+ G G+ G G Sbjct: 568 APGLPGLPGTP---GQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG 624 Query: 313 RGPKGYKGEKGKRGI------DGVDGVKGEMG----YPGLPGCKGSPGFD---GIQGPPG 359 GP G GEKG +G+ G+ G KG+ G PG PG G+PG D G+ G PG Sbjct: 625 FGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPG 684 Query: 360 PKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDG 419 G PG G+ G KGEPG G G PG GP G G PG PG PG G G EG PGP G Sbjct: 685 LPGQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPG 743 Query: 420 APGERGG-----PGERGPRGTPGTR---GPRGDPGEAGPQGDQGREGPVGVPGDPGEAGP 471 PG +G PG GP G PG + GP+GD G GP G GR G G+PG G+ GP Sbjct: 744 FPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGP 803 Query: 472 IGPKGYRGDEGPP-----GSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPG 526 G G G G P G G G PGP G PG G+ GE+G+ GP G G PG G Sbjct: 804 NGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERG 863 Query: 527 YPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQ 586 PG GAPG G G PGL G G +G PG +G G G GP GP G PG Sbjct: 864 SPGIPGAPGPIGPPGSPGLPGKAGASGFPG-------TKGEMGMMGPPGPPGPLGIPGRS 916 Query: 587 GPPG 590 G PG Sbjct: 917 GVPG 920 Score = 261 bits (666), Expect = 3e-69 Identities = 176/457 (38%), Positives = 203/457 (44%), Gaps = 124/457 (27%) Query: 257 GPPGLRGDPG-------------FEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGE 303 GPPG+RG PG G+RGKPG GE G+ G PG PGD G G G GE Sbjct: 270 GPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGE 329 Query: 304 KGSRGEKGSRGPKGYK----------GEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDG 353 KG +G+ G GP G GEKG G+ G+ G KGE G+PG+ G G PG G Sbjct: 330 KGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG 389 Query: 354 --IQGPPGPKGDPGAFGLKGEKGEPGA--------DGEAGRPGSSGPSGDEG-------- 395 + GPPGP G PG G KG++G PG DG+ G PG GP G G Sbjct: 390 AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449 Query: 396 --QPGEPGPPG---------EKGEAGDEGN-------------------PGPDGAPGERG 425 +PG PGPPG E+G GD+G+ PG G PG G Sbjct: 450 ICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLG 509 Query: 426 GPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGD----------PGEAGPIGPK 475 PG++G +G G GP+G PG G G G G G PGD GE G G Sbjct: 510 FPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAP 569 Query: 476 GYRGDEGPPGSEGARGAPGPAG------------PPGDPGLMGERGEDGPAG-------- 515 G G G PG +G G PGP G PPG+PGL G G GP G Sbjct: 570 GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG 629 Query: 516 -------NGTEGFPGFPGYPGNRGAPGIN-------GTKGYPGLKGDEGEAGDPGDDNND 561 G G PG PG PG +G PG G G PG GD G GDPG Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689 Query: 562 IAPRGVKGAK--------GYRGPEGPQGPPGHQGPPG 590 P G+ G+K G GP GP+G PG GPPG Sbjct: 690 GLP-GIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPG 725 Score = 221 bits (563), Expect = 3e-57 Identities = 129/306 (42%), Positives = 149/306 (48%), Gaps = 44/306 (14%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPG--DLGPVGYQGMKGEKGSRGEKGSRG 314 G PG G PG +G+ G+ G+PG G+ G+PG+PG + GP G G+ G+KG G G G Sbjct: 1155 GHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPG 1214 Query: 315 PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCK--------------GSPGFDGIQGPPGP 360 G G KG+ G G GV+G G PG PG G PGF G+ GP GP Sbjct: 1215 NPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGP 1274 Query: 361 KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA 420 G PG G+KGEKG PG G G PG G G G G PG PG G GD G PG G Sbjct: 1275 PGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGF 1334 Query: 421 PGERGG---PGERGPRGTPGTRGPRGDPGEAGPQGD----QGREGPVGVPGDPGEAG--- 470 PG +G PG GP G PG GP G PG GP G +G GP G+PG PG G Sbjct: 1335 PGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPG 1394 Query: 471 PIGPKGYRGDEGPPGSEGARGAPG------------------PAGPPGDPGLMGERGEDG 512 P GP+G G GPPG G G PG G G PG G +G G Sbjct: 1395 PQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPG 1454 Query: 513 PAGNGT 518 P G + Sbjct: 1455 PPGTSS 1460 Score = 220 bits (561), Expect = 5e-57 Identities = 138/348 (39%), Positives = 156/348 (44%), Gaps = 86/348 (24%) Query: 329 GVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD------------------------- 363 G+ G KGE G+PGL G G PGF G +GPPGP+G Sbjct: 42 GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP 101 Query: 364 --------------------PGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGP- 402 PG G KGE+G PG+ G G G GP G G GEPG Sbjct: 102 GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSI 161 Query: 403 -----PGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGR- 456 PG KG G G PG G PG G PG GP G PG GP G PG GP+G+ G Sbjct: 162 IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLN 221 Query: 457 -EGPVGVPGDPGEAGPIGPKG-------------YRGDEGPPGSEGARGAPGPAGPPGDP 502 +GP G G+ G GP GP G +GD+G PG G G PG GPPG P Sbjct: 222 FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPP 281 Query: 503 -GLMGERGEDG-------PAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGD 554 G GE+GE G P +G G PG PG PG+ G PG G G G KGD G G Sbjct: 282 GGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGP 341 Query: 555 PG------------DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 PG + +I G+ G KG RG G QGPPG GPPG Sbjct: 342 PGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG 389 Score = 172 bits (436), Expect = 1e-42 Identities = 101/233 (43%), Positives = 126/233 (54%), Gaps = 21/233 (9%) Query: 256 RGPPGLRGDPG--FEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQG---MKGEKGSRGEK 310 +GPPG G PG EG +G PG G G G G PG GP G G +KGEKG+ G+ Sbjct: 1234 QGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQP 1293 Query: 311 GSRGPKGYKGEKGKRGIDG------VDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDP 364 G G G KG++G G+ G ++G+KG+ G PG+PG G G G+ G GP+G+P Sbjct: 1294 GLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEP 1353 Query: 365 GAFGLKGEKGEPGADGEA-GRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGE 423 G G G G PG G++ G +GP G GQPG G PG + G +G PGP G PG+ Sbjct: 1354 GLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQ---GPQGLPGPTGPPGD 1410 Query: 424 RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKG 476 PG G G G G +GDPG G G +G +GP PG G GP GP G Sbjct: 1411 ---PGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGP---PGPDGLQGPPGPPG 1457 Score = 161 bits (408), Expect = 3e-39 Identities = 103/251 (41%), Positives = 115/251 (45%), Gaps = 36/251 (14%) Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436 G EA P G G GE+G G EG+PG G PG G PG RG +G Sbjct: 21 GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80 Query: 437 GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY------RGDEGPPGSEGAR 490 G GP G G GP G G G G+PG PG G GP+G +G+ G PGS G Sbjct: 81 GIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP 140 Query: 491 GAPGPAGPPGDPGLMGERGE------DGPAGN-GTEGFPGFPGYPGNRGAPGINGTKGYP 543 G GP GPPG PG+ GE G GP GN G G PG G PG G PG G G P Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPP 200 Query: 544 GLKGDEGEAGDPGDDN----NDIAPRGVKGAKGYRGPEGP-------------------Q 580 GL G G G PG N P+G KG +G +GP GP Q Sbjct: 201 GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQ 260 Query: 581 GPPGHQGPPGP 591 G PG +GPPGP Sbjct: 261 GLPGDRGPPGP 271 Score = 131 bits (330), Expect = 3e-30 Identities = 82/190 (43%), Positives = 96/190 (50%), Gaps = 37/190 (19%) Query: 257 GPPGLRGDPGFEGERGKPG------LPGEKGEAGDPGRPGDLGPVGYQGMKGE------- 303 GPPGL G+ G +GE+G PG LPG KG+ G PG G+ G G GMKG+ Sbjct: 1273 GPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVP 1332 Query: 304 -----KGSRGEKGSRGPKGYKGEKGKRGIDGVDG-------VKGEMGYPGLPG---CKGS 348 KG G GS GP+G G G G G+ G +KG+ G PG+PG KG Sbjct: 1333 GFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGL 1392 Query: 349 PGFDGIQG---PPGPKGDPGAFGLKG------EKGEPGADGEAGRPGSSGPSGDEGQPGE 399 PG G QG P GP GDPG GL G KG+PG G+ G G GP G +G G Sbjct: 1393 PGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGP 1452 Query: 400 PGPPGEKGEA 409 PGPPG A Sbjct: 1453 PGPPGTSSVA 1462 Score = 52.4 bits (124), Expect = 2e-06 Identities = 27/62 (43%), Positives = 29/62 (46%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312 Q +G PG G PG G G PG G G GDPG PG G G G G G +G G Sbjct: 1396 QGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGP 1455 Query: 313 RG 314 G Sbjct: 1456 PG 1457 Score = 52.0 bits (123), Expect = 3e-06 Identities = 30/75 (40%), Positives = 36/75 (48%), Gaps = 3/75 (4%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 +G PG +G G G G PG PG G PG G G G G+ G+ G+RG G GP Sbjct: 1390 KGLPGPQGPQGLPGPTGPPGDPGRNGL---PGFDGAGGRKGDPGLPGQPGTRGLDGPPGP 1446 Query: 316 KGYKGEKGKRGIDGV 330 G +G G G V Sbjct: 1447 DGLQGPPGPPGTSSV 1461 >gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] Length = 1714 Score = 297 bits (761), Expect = 3e-80 Identities = 168/375 (44%), Positives = 202/375 (53%), Gaps = 40/375 (10%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G PG G G G+RG+PG G+KG+ G G G GP G G G KG+RG +G+ G Sbjct: 1098 GLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHL 1157 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDG----IQGPPGPKGDPGAFGLKGE 372 G G G+ GI G G +G+ G GLPG KG G+ G + GPPGP+G+PG G +GE Sbjct: 1158 GLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGE 1217 Query: 373 KGEPGADGEAGR---PGSSGPSGDEGQPGEPGPPGE---KGEAGDEGNPGPDGAPGERGG 426 +GEPGA+G G PG G +G +G PGEPG GE KGE G EGN G GAPG G Sbjct: 1218 RGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGK 1277 Query: 427 PG---------ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY 477 PG +G +G G G G+PG+ GP G QG G G PG G AG GP G Sbjct: 1278 PGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGV 1337 Query: 478 RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGI 536 +G G PGS G +G G G PG PG+ G+RG G G+ G G PG G PG G G+ Sbjct: 1338 KGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGL 1397 Query: 537 NGTKGYPGLKGDEGEAG-----------------DPGDDNNDIAPRG---VKGAKGYRGP 576 G +G+PG KG EG+AG P I P G +G KG+RG Sbjct: 1398 TGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGE 1457 Query: 577 EGPQGPPGHQGPPGP 591 GPQGP G GPPGP Sbjct: 1458 TGPQGPRGQPGPPGP 1472 Score = 278 bits (712), Expect = 1e-74 Identities = 159/350 (45%), Positives = 189/350 (54%), Gaps = 17/350 (4%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMK------GEKGSRGEK 310 GPPG G PG G+RG G+PG G G PG PG GP G G GEKG +G Sbjct: 498 GPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLS 557 Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA---- 366 G GP G +G+KG +G G+ G+ GE G PG G GSPG+ G QG GP+G+PG Sbjct: 558 GLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQ 617 Query: 367 --FGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGER 424 G GE G+ G +GE G PG G G +G+ G PG G++G AG +G+PG G G Sbjct: 618 GFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPP 677 Query: 425 GGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGP- 483 G PG RG G G GP G PG G G++G G G G+ G AG +G GY GD+G Sbjct: 678 GFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAV 737 Query: 484 --PGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGTK 540 PG G RG GP+G GDPGL G G GP G G G PG G G +G G G Sbjct: 738 GLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPP 797 Query: 541 GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G PGLKG +GE G P ++ PRG G KGY G GP+G G G G Sbjct: 798 GPPGLKGTQGEEG-PIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQG 846 Score = 273 bits (697), Expect = 8e-73 Identities = 160/359 (44%), Positives = 190/359 (52%), Gaps = 27/359 (7%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKG------EAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310 GPPG++GD G +G G PGLPGE+G G PG PG G G +G G KG++G Sbjct: 561 GPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFI 620 Query: 311 GSRGPKGYKGEKGKRGIDGV---DGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAF 367 GS G G G +G+RGI G+ G KG G+PG G +G G DG G G G PG Sbjct: 621 GSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFP 680 Query: 368 GLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGP 427 GL+G G G G AG PG G SG++G PG G GE+G AG+ G PG PG++G Sbjct: 681 GLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPG---YPGDKGAV 737 Query: 428 GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGD---PGEAGPIGPKGYRGDEGPP 484 G GP G G GP G G+ G QG G GP G PGD PG+ GP GPKG G+ GPP Sbjct: 738 GLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPP 797 Query: 485 GSEGARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFPGYPGNRGAPGINGTK 540 G G +G G GP G G +G RG+ G G G EG G G GN G G G Sbjct: 798 GPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPV 857 Query: 541 GYPGLKGDEGEAGDPGDDNN--DIAPRGVKGAKGYRGPEGPQGP------PGHQGPPGP 591 G PG G G G+ G+ + + P+G KG GY GP G GP PGH G GP Sbjct: 858 GLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGP 916 Score = 272 bits (696), Expect = 1e-72 Identities = 163/371 (43%), Positives = 191/371 (51%), Gaps = 39/371 (10%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGE---------AGDPGRPGDLGPVGYQGMKGEKGS 306 RGP GL G PG G G PG PG +G AG PG G G G G+KG+KG Sbjct: 659 RGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGE 718 Query: 307 RGEKGSRGPKGYKGEKGKRGIDGVDGVKG------EMGYPGLPGCKGSPGFDGI------ 354 +G G G GY G+KG G+ G G++G + G PGL G G PG +G Sbjct: 719 QGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGI 778 Query: 355 ---QGPPGPKG------DPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGE 405 GP GPKG PG GLKG +GE G G G G G G +G GEPGP G Sbjct: 779 PGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGL 838 Query: 406 KGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGD 465 KGE GD+GN G G G G PGE G G+ G +G RG PG GPQG++G G G PG Sbjct: 839 KGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGV 898 Query: 466 PGEAGPIGPKGYRGDEGPPGSE---GARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGF 521 PG GP+G G+ G GPPGS+ G RG+ GP G G+ G+ G +GE G G G G Sbjct: 899 PGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGL 958 Query: 522 PGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPG--DDNNDIAPRGVKGAKGYRGPEGP 579 G G PG RG G G +G PG GD G G+PG D+ P G G GP G Sbjct: 959 IGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGP---PGEMGMEGPPGT 1015 Query: 580 QGPPGHQGPPG 590 +G G QG PG Sbjct: 1016 EGESGLQGEPG 1026 Score = 268 bits (686), Expect = 1e-71 Identities = 156/353 (44%), Positives = 187/353 (52%), Gaps = 24/353 (6%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RG PG+RG GF+G +G PG G++G AG G PG +G G G G +GS G G GP Sbjct: 635 RGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGP 694 Query: 316 KGYKGEKGKRGIDGVDGVKG---------EMGYPGLPGCKGS------PGFDGIQGPPGP 360 G G G G G+ G+KG E+G PG PG KG+ PG G GP G Sbjct: 695 AGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQ 754 Query: 361 KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDE---GQPGEPGPPGEKGEAGDEGNPGP 417 GDPG G G G G G+ G PG +GP G + G G PGPPG KG G+EG G Sbjct: 755 TGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGA 814 Query: 418 DGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY 477 G G RG PG++G G PG G +G+ G+ G G G GPVG+PG+ G G IG KG Sbjct: 815 FGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGE 874 Query: 478 RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGIN 537 RG GP G +G +G G GPPG PG +G G G G G PG G G RG+ G + Sbjct: 875 RGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHV--GARGPPGSQGPKGQRGSRGPD 932 Query: 538 GTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G G G++G +GE GD G P G+ G G G G QG PG QG PG Sbjct: 933 GLLGEQGIQGAKGEKGDQGKR----GPHGLIGKTGNPGERGFQGKPGLQGLPG 981 Score = 267 bits (682), Expect = 4e-71 Identities = 161/370 (43%), Positives = 195/370 (52%), Gaps = 37/370 (10%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGE------KGEAGDPGRPGDLGPVGYQGMKGEKGSRG 308 ARGPPG +G G G RG GL GE KGE GD G+ G G +G G GE+G +G Sbjct: 913 ARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQG 972 Query: 309 EKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFD---GIQGPPGPKGDPG 365 + G +G G G++G G G+ G++G++G PG G +G PG + G+QG PG KGD G Sbjct: 973 KPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVG 1032 Query: 366 AFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGP---PGEKGEAGDEGNPGPDGAPG 422 G G GEPG GE G PG G G +G G PG PGE GE G+ G PG G G Sbjct: 1033 TAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLG 1092 Query: 423 ERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYR---- 478 G G GP G G G RG PG+ G +G G G VG G PG+ G GPKG R Sbjct: 1093 RSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRG 1152 Query: 479 -----------GDEGPPGSEGARGAPGPAGPPGDPGLMGERGED----GPAGNGTEGFPG 523 G+ G PG G +G PGP+G PG G G GED GP G G PG Sbjct: 1153 AVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPP--GPRGEPG 1210 Query: 524 FPGYPGNRGAPGINGTKGY---PGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQ 580 G G RG PG G KG+ PGL+G G+ G PG+ D +G+KG +G G +G + Sbjct: 1211 PVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEP-GDQGEQGLKGERGSEGNKGKK 1269 Query: 581 GPPGHQGPPG 590 G PG G PG Sbjct: 1270 GAPGPSGKPG 1279 Score = 266 bits (680), Expect = 7e-71 Identities = 161/371 (43%), Positives = 194/371 (52%), Gaps = 40/371 (10%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRG------EK 310 GP G +G+ G G G PG+PG G G PG G GP G QG KG++GSRG E+ Sbjct: 879 GPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQ 938 Query: 311 GSRGPKGYKGEKGKRGIDGV---DGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAF 367 G +G KG KG++GKRG G+ G GE G+ G PG +G PG G +G PG +PG Sbjct: 939 GIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPG---EPGLR 995 Query: 368 GLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPG---PDGAPGER 424 GL+G+ G PG G G PG+ G SG +G+PG G G G G G PG GAPGE Sbjct: 996 GLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEE 1055 Query: 425 GGPGERGPRGTPGTRGPRGDPGEAGP------------QGDQGREGPVGVPGDPGEAGPI 472 G G+ G +G PG RG G+ GE G G G GP G+ G PG+ G Sbjct: 1056 GLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRP 1115 Query: 473 GPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGY---- 527 G KG +G GP G G+RG PG G G G G RG G G G +G PG PGY Sbjct: 1116 GKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQ 1175 Query: 528 --PGNRGAPGINGTKGYPG----LKGDEGEAGDPG--DDNNDIAPRGVKGAKGYRGPEGP 579 PG G PG G KGYPG + G G G+PG D + G +G KG+ G G Sbjct: 1176 GQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGL 1235 Query: 580 QGPPGHQGPPG 590 +G G QGPPG Sbjct: 1236 RGATGQQGPPG 1246 Score = 265 bits (676), Expect = 2e-70 Identities = 162/395 (41%), Positives = 198/395 (50%), Gaps = 71/395 (17%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGE------KGSRGEK 310 G PG +G PGF G G PG PG +G AG G PG G G+ G GE +G RG Sbjct: 579 GLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIP 638 Query: 311 GSRGPKGYKG---------EKGKRGIDGVDGVKGEMGYPGLPGCKGSPGF------DGIQ 355 G RG KG+KG ++G G+DG G+ G G PG PG +GS G GI Sbjct: 639 GIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIP 698 Query: 356 GPPGPKGDPGAFGLKGEKGEPGADGEAGRPG------------------SSGPSGDEGQP 397 GP G G+ G G+KG+KGE G GE G PG SGPSG G P Sbjct: 699 GPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDP 758 Query: 398 GEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGRE 457 G GP G PGP+G PG+ G PG+ GP G G G RG PG G +G QG E Sbjct: 759 GLQGP---------SGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEE 809 Query: 458 GPVGV---------PGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGL---- 504 GP+G PG G AG GP+G +G+ G G+ G G GP G PG+ G+ Sbjct: 810 GPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSI 869 Query: 505 --MGERGEDGPAG----NGTEGFPGFPGYP---GNRGAPGINGTKGYPGLKGDEGEAGDP 555 GERG GP G G G+PG PG P G G PG G +G PG +G +G+ G Sbjct: 870 GEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSR 929 Query: 556 GDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G D + +G++GAKG +G +G +GP G G G Sbjct: 930 GPDGL-LGEQGIQGAKGEKGDQGKRGPHGLIGKTG 963 Score = 264 bits (674), Expect = 4e-70 Identities = 159/379 (41%), Positives = 186/379 (49%), Gaps = 48/379 (12%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GPPG+RG G G+ G PGL G G G G PGD+G G G +G KG G +G GP Sbjct: 741 GPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPP 800 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376 G KG +G+ G G G G G PG G G PG +G++G G D G G GE G Sbjct: 801 GLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVG---DQGNIGKIGETGPV 857 Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436 G GE G GS G G+ G PG GP GEKG G G PG G G G PG G RG P Sbjct: 858 GLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPP 917 Query: 437 GTRGPRGDPGEAGPQ---GDQGREGPVGVPGDPGEAGP------IGPKGYRGDEGPPGSE 487 G++GP+G G GP G+QG +G G GD G+ GP G G RG +G PG + Sbjct: 918 GSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQ 977 Query: 488 GARGAPGPAGPPGDPGLMGERGEDGPAGN-------GTEGFPGFPGYPGNR--------- 531 G G+ G G PG+PGL G +G+ GP G GTEG G G PG + Sbjct: 978 GLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSV 1037 Query: 532 ------------GAPGINGTKGYPGLKGDEGEAGDPGDDNND--------IAPRGVKGAK 571 GAPG G +G GLKG G G PG+D I P G G Sbjct: 1038 GGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQT 1097 Query: 572 GYRGPEGPQGPPGHQGPPG 590 G GPEG G PG +G PG Sbjct: 1098 GLPGPEGIVGIPGQRGRPG 1116 Score = 263 bits (671), Expect = 8e-70 Identities = 163/383 (42%), Positives = 193/383 (50%), Gaps = 48/383 (12%) Query: 257 GPPGLRGDPGFEG------ERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRG-- 308 GPPGL+G G EG E G G PG+KG AG+PG G G VG QG G+ G G Sbjct: 798 GPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPV 857 Query: 309 ----EKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDP 364 E G G G KGE+G G G G KG MGYPG PG G G G+ G G +G P Sbjct: 858 GLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPP 917 Query: 365 GAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGER 424 G+ G KG++G G DG G G G G++G G+ GP G G+ G+ G G G PG + Sbjct: 918 GSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQ 977 Query: 425 GGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGP------VGVPGDPGEAGPI------ 472 G PG G RG PG G RG G+ GP G+ G EGP G+ G+PG G + Sbjct: 978 GLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSV 1037 Query: 473 ---GPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFP 525 G G RG+ G PG EG +G G G PG GL GE GE G G G G G Sbjct: 1038 GGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQT 1097 Query: 526 GYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAP-----------RGVKGAKGYR 574 G PG G GI G +G PG KGD+G+ G G+ + P RG +GA G+ Sbjct: 1098 GLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHL 1157 Query: 575 GPEGPQGPP------GHQGPPGP 591 G GP G P GHQG PGP Sbjct: 1158 GLMGPDGEPGIPGYRGHQGQPGP 1180 Score = 258 bits (660), Expect = 2e-68 Identities = 172/417 (41%), Positives = 200/417 (47%), Gaps = 85/417 (20%) Query: 253 QPARGPPGL---RGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQG---MKGEKGS 306 Q RGP GL G+PG G +GKPGL G G GD G PG+ G G QG GE G Sbjct: 950 QGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGM 1009 Query: 307 RGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366 G G+ G G +GE G +G G G G G PGL G G+PG +G+QG G KG PG Sbjct: 1010 EGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGG 1069 Query: 367 FGLKGEKGEPGADGEAGR---PGSSGPSGDEGQPGEPGP------PGEK---GEAGDEGN 414 GL PG DGE G PG GP G GQ G PGP PG++ G+ GD+G Sbjct: 1070 RGL------PGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQ 1123 Query: 415 PGPDGAPGERGGP---GERGPRGTPGTR---------GPRGDPGEAGPQGDQGREGPVGV 462 GP G G RG P G+ GP+G GTR GP G+PG G +G QG+ GP G+ Sbjct: 1124 IGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGL 1183 Query: 463 PGDPGEAG-------PIGPKGYRGDEGPPGSEGARGAP------------------GPAG 497 PG GE G +GP G RG+ GP G +G RG P G G Sbjct: 1184 PGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQG 1243 Query: 498 PPGDP------GLMGERGEDGPAGN----GTEGFPGFPGYPGNRGAPGINGTKGYPGLKG 547 PPG+P GL GERG +G G G G PG PG G G GI G G G+ G Sbjct: 1244 PPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISG 1303 Query: 548 DEGEAGDPGDDN--------------NDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 + G+ G PG P GVKG+ G G G QGP G QG PG Sbjct: 1304 NPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPG 1360 Score = 256 bits (653), Expect = 1e-67 Identities = 151/346 (43%), Positives = 180/346 (52%), Gaps = 13/346 (3%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RGPPG G G +GE G G GE G G PG+ G G G +G+KGE G +G G G Sbjct: 794 RGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGE 853 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375 G G G+ G+ G G KGE G PG G +G G G GPPG G G GL G G Sbjct: 854 TGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGA 913 Query: 376 PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGT 435 G G G G G G +G GE G G KGE GD+G GP G G+ G PGERG +G Sbjct: 914 RGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGK 973 Query: 436 PGTRGPRGDPGEAGPQGD---QGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGA 492 PG +G G G+ G G+ +G +G VG PG+ G GP G +G G +G PG++G G Sbjct: 974 PGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGT 1033 Query: 493 PGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLK------ 546 G G G+PGL GE G P G +G G G PG RG PG +G KG GL Sbjct: 1034 AGSVGGTGEPGLRGEPG--APGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPL 1091 Query: 547 GDEGEAGDPGDDNNDIAP--RGVKGAKGYRGPEGPQGPPGHQGPPG 590 G G+ G PG + P RG G KG +G GP G G +GPPG Sbjct: 1092 GRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPG 1137 Score = 244 bits (623), Expect = 3e-64 Identities = 137/287 (47%), Positives = 158/287 (55%), Gaps = 8/287 (2%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GPPG RG+PG G++G+ G PG +G G G PG G G QG GE G +GE+G +G + Sbjct: 1201 GPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGER 1260 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGF---DGIQGPPGPKGDPGAFGLKGEK 373 G +G KGK+G G G G G GL G KG G+ DGI G PG G PG GL G + Sbjct: 1261 GSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIR 1320 Query: 374 GEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPR 433 G PG G AG PG G G G PG PG G KGE G G PG G G RG G++GP Sbjct: 1321 GGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPC 1380 Query: 434 GTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGE---AGPIGPKGYRGDEGPPGSEGAR 490 G PG +G G+ G G G QG GP G GD G +GP GP G+RG+ GP G EG Sbjct: 1381 GDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGII 1440 Query: 491 GAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGIN 537 G G GP G+ G GE G GP G G PG PG PG R IN Sbjct: 1441 GPTGRTGPRGEKGFRGETGPQGP--RGQPGPPGPPGAPGPRKQMDIN 1485 Score = 239 bits (611), Expect = 7e-63 Identities = 145/356 (40%), Positives = 176/356 (49%), Gaps = 43/356 (12%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGS-RGEKGSR 313 ARG G G G G G+PG+PG +G G PG G GP G +G GE + G G R Sbjct: 1147 ARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPR 1206 Query: 314 GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGC---KGSPGFDGIQGPPGPKGDPGAFGLK 370 G G G++G+RG G +G KG +G PGL G +G PG G QG G KG+ G+ G K Sbjct: 1207 GEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNK 1266 Query: 371 GEKGEPGADGEAGRPGSSG------------PSGDEGQPGEPGPPGEKGEAGDEGNPGPD 418 G+KG PG G+ G PG G G G PG+ GPPG++G G G PG Sbjct: 1267 GKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRT 1326 Query: 419 ---GAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475 GAPG G G G G+PG +GP+G+ G G G QG+ G G GD G G G K Sbjct: 1327 GLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLK 1386 Query: 476 GYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPG 535 G G+ G G G +G PGP GP GD G++G G GP G+ GN G G Sbjct: 1387 GQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPI-----------GHRGNTGPLG 1435 Query: 536 INGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G G G G GE +G +G G +GP G GPPG G PGP Sbjct: 1436 REGIIGPTGRTGPRGE-------------KGFRGETGPQGPRGQPGPPGPPGAPGP 1478 Score = 150 bits (380), Expect = 5e-36 Identities = 87/209 (41%), Positives = 98/209 (46%), Gaps = 24/209 (11%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG--- 311 A GP G G PG +G G G+ G G G G PG +GP G QG+ G +G G G Sbjct: 1271 APGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAG 1330 Query: 312 SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKG 371 + GP G KG G G G+ G KGE G PG PG +G G G QG GP GDPG G G Sbjct: 1331 APGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPG 1390 Query: 372 EKGEPGADGEAGRPGSSGPSGDEG---------------------QPGEPGPPGEKGEAG 410 E G G G G PG GP GD G + G GP G G G Sbjct: 1391 EYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRG 1450 Query: 411 DEGNPGPDGAPGERGGPGERGPRGTPGTR 439 ++G G G G RG PG GP G PG R Sbjct: 1451 EKGFRGETGPQGPRGQPGPPGPPGAPGPR 1479 Score = 103 bits (257), Expect = 8e-22 Identities = 61/155 (39%), Positives = 76/155 (49%), Gaps = 27/155 (17%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312 Q +G GL G PG +G+RG G G++G GDPG G G G QG+ G +G G Sbjct: 1350 QGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGP--- 1406 Query: 313 RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372 KG +G GI G+ G KG +G+ G G G G G G GP+G+ KG Sbjct: 1407 ------KGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGE------KGF 1454 Query: 373 KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKG 407 +GE +GP G GQPG PGPPG G Sbjct: 1455 RGE------------TGPQGPRGQPGPPGPPGAPG 1477 Score = 43.9 bits (102), Expect = 8e-04 Identities = 24/56 (42%), Positives = 27/56 (48%), Gaps = 7/56 (12%) Query: 536 INGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 + G KG G G G AG PG P G +G +G GP G G PG GP GP Sbjct: 487 LRGPKGDTGPPGPPGPAGIPG-------PSGKRGPRGIPGPHGNPGLPGLPGPKGP 535 >gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] Length = 680 Score = 295 bits (754), Expect = 2e-79 Identities = 183/433 (42%), Positives = 218/433 (50%), Gaps = 96/433 (22%) Query: 253 QPARGPPGLRGDPGFEG--------ERGKPGLPGEKGEAGDPGRPGDLGPVGYQG----- 299 +P G PGL+G+PG G + G PGLPG+ GE G G GD+GP G G Sbjct: 82 KPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPP 141 Query: 300 ------------MKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGY--PGLPGC 345 + G+ G +G G+ GP+G+ GEKG G+ G++G KGEMGY PG PG Sbjct: 142 GPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGE 201 Query: 346 KGSPGFDGIQGPPGP--------KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDE--- 394 +G PG G GP GP G PG G+KG++G PG G G PG GP G+ Sbjct: 202 RGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPE 261 Query: 395 --------GQPGEPGPPGEKGEAGDEGNPGPDGAP-----------GER------GGP-- 427 G PG+PG PG KG G G GP G P GER GGP Sbjct: 262 GIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGA 321 Query: 428 -GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY---RGDEGP 483 GE+GP G PG G G PG GPQG +G G G+PG GE GP GP GY +G+ G Sbjct: 322 KGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGS 381 Query: 484 PGS------------EGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGN 530 PGS +G +G PG GP GDPG+ G G GP G G +G PG G G Sbjct: 382 PGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGP 441 Query: 531 RGAPGINGTK---------GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQ- 580 RGAPGI GT+ G+PG KGD G G PG IA +G+ G G GP GP+ Sbjct: 442 RGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAG--IATKGLNGPTGPPGPPGPRG 499 Query: 581 --GPPGHQGPPGP 591 G PG GPPGP Sbjct: 500 HSGEPGLPGPPGP 512 Score = 260 bits (664), Expect = 5e-69 Identities = 153/364 (42%), Positives = 182/364 (50%), Gaps = 53/364 (14%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGD-----PGRPGDLGPVGYQG----------- 299 +GP G G GF GE+G PG+PG G+ G+ PGRPG+ G G QG Sbjct: 161 QGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVG 220 Query: 300 ------------MKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVD--GVKGEMGYPGLPGC 345 +KG++G GE G GP G +G G+RG +G+ G G G PG+PG Sbjct: 221 KRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGT 280 Query: 346 KGSPGFDGIQGPPGPKG--DPGAFGLKGEKGE------PGADGE------------AGRP 385 KG PG GI GPPGP G PG GLKGE+G PGA GE G P Sbjct: 281 KGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPP 340 Query: 386 GSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRG---TPGTRGPR 442 G+ GP G +G PG G PG KGE G G G GA GERG PG G G PG GP+ Sbjct: 341 GNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPK 400 Query: 443 GDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDP 502 G+PG GP+GD G GP G+PG G AG G G+ G+ GP G+ G G GP GPPG P Sbjct: 401 GNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIP 460 Query: 503 GLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDI 562 G G +G+ G G G G G PG G +G+ G G G G PG + Sbjct: 461 GFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAV 520 Query: 563 APRG 566 P G Sbjct: 521 MPEG 524 Score = 241 bits (616), Expect = 2e-63 Identities = 152/348 (43%), Positives = 175/348 (50%), Gaps = 32/348 (9%) Query: 271 RGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGV 330 RG+ G PG G AG G PG GP G G G G +GE G GP G GK G+ G+ Sbjct: 56 RGEQGTPGPPGPAGPRGHPGPSGPPGKPGY-GSPGLQGEPGLPGPPG-PSAVGKPGVPGL 113 Query: 331 DGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGP 390 G GE G G G G G G +GPPGP G PG G+ G+PG G G PG G Sbjct: 114 PGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGIS-VPGKPGQQGPTGAPGPRGF 172 Query: 391 SGDEGQPGEPGPPGEKGEAG--DEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEA 448 G++G PG PG G+KGE G G PG G PG +G G GP G G RG G PG+ Sbjct: 173 PGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGV-GKRGENGVPGQP 231 Query: 449 GPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGA------------RGAPGPA 496 G +GD+G G +G G PG GP G +G G G PG+ GA GAPG A Sbjct: 232 GIKGDRGFPGEMGPIGPPGPQGPPGERGPEGI-GKPGAAGAPGQPGIPGTKGLPGAPGIA 290 Query: 497 GPP-----GDPGLMGERGEDGPAG-------NGTEGFPGFPGYPGNRGAPGINGTKGYPG 544 GPP G PGL G +GE GPAG G +G G PG PG G PG G +G G Sbjct: 291 GPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKG 350 Query: 545 LKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592 + G G G P + P G GAKG RG G G PG+ G PG D Sbjct: 351 IPGSHGLPG-PKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLD 397 Score = 233 bits (594), Expect = 7e-61 Identities = 157/423 (37%), Positives = 181/423 (42%), Gaps = 131/423 (30%) Query: 300 MKGEKGSRGEKGSRGPKGYKGEK----------------------------GKRGIDGVD 331 ++GE+G+ G G GP+G+ G GK G+ G+ Sbjct: 55 VRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLP 114 Query: 332 ---------GVKGEMGYPGLPGCKGSPGFDGIQGP-----------------------PG 359 G KG++G GLPG +G PG GI GP PG Sbjct: 115 GKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPG 174 Query: 360 PKGDPGAFGLKGEKGE-----PGADGEAGRPGSSGPSGDEGQP--------GEPGPPGEK 406 KG PG G+ G+KGE PG GE G PG GP+G G P G PG PG K Sbjct: 175 EKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIK 234 Query: 407 GEAGDEGNPGPDGAPGERGGPGERGPR--------------GTPGTRGPRGDPGEAGPQG 452 G+ G G GP G PG +G PGERGP G PGT+G G PG AGP G Sbjct: 235 GDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPG 294 Query: 453 D-----------QGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGD 501 +G GP G+PG PG G GP G G G G G G GP G PG Sbjct: 295 PPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGS 354 Query: 502 PGLMGERGEDGPAG-------NGTEGFPGFPGYPGNRGAPGINGTKGYPGL---KGDEGE 551 GL G +GE GPAG G G PG G PG G PG++G KG PGL KGD G Sbjct: 355 HGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGV 414 Query: 552 AGDPG--------------DDNNDIAPRGVKGAKGYRGPEGP---------QGPPGHQGP 588 G PG N + PRG G G RGP GP +G PG GP Sbjct: 415 GGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGP 474 Query: 589 PGP 591 PGP Sbjct: 475 PGP 477 Score = 226 bits (576), Expect = 9e-59 Identities = 141/330 (42%), Positives = 161/330 (48%), Gaps = 50/330 (15%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPG-----RPGDLGPVGYQGMKGEKGSRGEKG 311 G PG++GD GF GE G G PG +G G+ G +PG G G G+ G KG G G Sbjct: 229 GQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPG 288 Query: 312 SRGPKG-----------YKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP 360 GP G KGE+G G+ G G KGE G GLPG G G G GP GP Sbjct: 289 IAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGP 348 Query: 361 KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGD---EGQPGEPGPPGEKGEAGDEGNPGP 417 KG PG+ GL G KGE G G AG PG+ G G +G+PG PG PG G G+ G PGP Sbjct: 349 KGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGP 408 Query: 418 DGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQG---REGPVGVPG---------D 465 G PG G PG GP G G +G G GEAGP+G G GP+G PG D Sbjct: 409 KGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGD 468 Query: 466 PGEAGPIGP-----KGYRGDEGPPGSEGARG---APGPAGPPGDPGLMGERGEDGPAGNG 517 PG GP GP KG G GPPG G RG PG GPPG P GP G Sbjct: 469 PGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPP---------GPPGQA 519 Query: 518 T--EGFPGFPGYPGNRGAPGINGTKGYPGL 545 EGF P G P ++ +G G+ Sbjct: 520 VMPEGFIKAGQRPSLSGTPLVSANQGVTGM 549 Score = 189 bits (479), Expect = 2e-47 Identities = 114/252 (45%), Positives = 126/252 (50%), Gaps = 15/252 (5%) Query: 254 PARGPPGLRGDPGFEGERGKPGLPGEKGE---AGDPGRPGDLGPVGYQGMKGEKGSRGEK 310 P G PGL G G G G PG PG KGE AG PG+PG GP G G +G KG G Sbjct: 296 PGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSH 355 Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370 G GPKG G G G G G +G G G PG G PG D GPKG+P GL Sbjct: 356 GLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLD------GPKGNP---GLP 406 Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGER 430 G KG+PG G G PG GP+G +G PG G G +G G G GP G PG G PG + Sbjct: 407 GPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSK 466 Query: 431 GPRGTPGTRGPRG--DPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE-GPPGSE 487 G G+PG GP G G GP G G GP G G+PG GP GP G G P G Sbjct: 467 GDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFI 526 Query: 488 GARGAPGPAGPP 499 A P +G P Sbjct: 527 KAGQRPSLSGTP 538 Score = 102 bits (254), Expect = 2e-21 Identities = 59/128 (46%), Positives = 66/128 (51%), Gaps = 9/128 (7%) Query: 472 IGPKGYRGDEGPPGSEGARGAPGPAGPP-----GDPGLMGERGEDGPAGN---GTEGFPG 523 I +G +G GPPG G RG PGP+GPP G PGL GE G GP G G G PG Sbjct: 53 IAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPG 112 Query: 524 FPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPG-DDNNDIAPRGVKGAKGYRGPEGPQGP 582 PG PG RG G G G GL G G G PG I+ G G +G G GP+G Sbjct: 113 LPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGF 172 Query: 583 PGHQGPPG 590 PG +G PG Sbjct: 173 PGEKGAPG 180 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 293 bits (751), Expect = 4e-79 Identities = 168/387 (43%), Positives = 197/387 (50%), Gaps = 45/387 (11%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 +G PG G PG G+ G PG PG KG G PG+PG +GP G +G G+ G G +G GP Sbjct: 984 QGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGP 1043 Query: 316 KGYKGEKGKRGIDGVDGVKGE--------MGYPGLPGCKGSPGFDGIQGPPGPKGD---- 363 G G G+ G G+ G KG+ +G PGLPG KG PG G G PG KG Sbjct: 1044 PGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP 1103 Query: 364 --PGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAP 421 PG G G KG+PG G G PG GP G G PG PG PGE G G G+PG G P Sbjct: 1104 GLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPP 1163 Query: 422 GERGGPGERGPRGTPGTRGPRGDPGEAGP--------QGDQGREGPVGVPGDPGEAGPIG 473 GE+G PG+ G G G +G G PG P G +G G G+PG+PG GP G Sbjct: 1164 GEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG 1223 Query: 474 PKGY------RGDEGPPGS-----EGARGAPGPAGPPGDPGLMGERGEDGPAGNG----- 517 G+ +G GPPGS EG +G PGP GPPG PGL G G G GNG Sbjct: 1224 EPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGE 1283 Query: 518 -----TEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN--NDIAPRGVKGA 570 G PG PG G++G PG+ G G PGL G +G+ G PG P GV G+ Sbjct: 1284 KGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGS 1343 Query: 571 KGYRGPEGPQGPPGHQGPPGPDECEIL 597 G G G GPPG G PGP I+ Sbjct: 1344 AGPEGEPGLIGPPGPPGLPGPSGQSII 1370 Score = 290 bits (741), Expect = 6e-78 Identities = 165/373 (44%), Positives = 195/373 (52%), Gaps = 57/373 (15%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPV-----GYQGMKGEKGSRGEKG 311 G PGL+GD G +G+ G PG GEKG G+PG PG GP+ G +G KGE G G G Sbjct: 917 GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPG 976 Query: 312 SRGPKGYKGE---------KGKRGIDGVDGVKGEMGYPGLPGCKGSPGF----------- 351 GPKGY+G G+ G+ G G KG G PG PG G PG Sbjct: 977 VSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG 1036 Query: 352 -DGIQGPPGPKG------DPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPG 404 G++GPPGP G PG G KG+KG+PG G PG GP G+ G PG PG PG Sbjct: 1037 PQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISS-IGLPGLPGPKGEPGLPGYPGNPG 1095 Query: 405 EKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPG 464 KG GD G PG G PG +G PG G GTPG GP+G G G G G GPVG G Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155 Query: 465 DPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAG-----PPGDPGLMGERGEDGPAGNGTE 519 PG+ GP G KG G +G PG G +G PG G PPG PGL G++G+ G Sbjct: 1156 HPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGD-----GGLP 1210 Query: 520 GFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGP 579 G PG PG PG +G PG +G +PG++G G G PG +G +G GP Sbjct: 1211 GIPGNPGLPGPKGEPGFHG---FPGVQGPPGPPGSPGP-----------ALEGPKGNPGP 1256 Query: 580 QGPPGHQGPPGPD 592 QGPPG G PGP+ Sbjct: 1257 QGPPGRPGLPGPE 1269 Score = 289 bits (740), Expect = 8e-78 Identities = 173/382 (45%), Positives = 194/382 (50%), Gaps = 51/382 (13%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMK------------- 301 A GP G G PG G+ G G PG KGE G G PG GP+G G Sbjct: 870 APGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQG 929 Query: 302 --------GEKGSRGEKGSRGPK--------GYKGEKGKRGIDGVDGVKGEMGYPGLPGC 345 GEKGS+GE G GP G KGEKG+ G+ G+ GV G GY GLPG Sbjct: 930 QPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD 989 Query: 346 KGSPGFD---GIQGPPGPKGDP---------GAFGLKGEKGEPGADGEAGRPGSSGPSGD 393 G PG G+ GPPGPKG+P G GLKG G+ G G G G GPSG Sbjct: 990 PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049 Query: 394 EGQPGEPGPPGEKGEAGDEG--NPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQ 451 GQPG PG PG+KG+ GD G + G G PG +G PG G G PG +G GDPG G Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLP 1109 Query: 452 GDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGED 511 G G +G G+PG PG GP GPKG GPPG+ G G PGP G G PG G GE Sbjct: 1110 GTPGAKGQPGLPGFPGTPGPPGPKGI---SGPPGNPGLPGEPGPVGGGGHPGQPGPPGEK 1166 Query: 512 GPAGNGTEGFPGFPGYPGNRGAPGIN--GTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKG 569 G G +G PG G G G PG G G PGL G +G+ G PG N P G KG Sbjct: 1167 GKPGQ--DGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLP-GPKG 1223 Query: 570 AKGYRGPEGPQGPPGHQGPPGP 591 G+ G G QGPPG G PGP Sbjct: 1224 EPGFHGFPGVQGPPGPPGSPGP 1245 Score = 289 bits (740), Expect = 8e-78 Identities = 168/372 (45%), Positives = 194/372 (52%), Gaps = 39/372 (10%) Query: 257 GPPGLRGDPG---FEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSR 313 GP G+ G PG G+ G PGLPG+KG+ GDPG +G G G KGE G G G+ Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI-SSIGLPGLPGPKGEPGLPGYPGNP 1094 Query: 314 GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKG---DPGAFGLK 370 G KG G+ G G+ G G KG+ G PG PG G PG GI GPPG G +PG G Sbjct: 1095 GIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGG 1154 Query: 371 GEKGEPGADGEAGRPGSSG---PSGDEGQPGEPG--------PPGEKGEAGDEGNPGPDG 419 G G+PG GE G+PG G P+G +G+PG+PG PG G+ GD G PG G Sbjct: 1155 GHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPG 1214 Query: 420 APGERGGPGERGPRGTPGTRGPRGDPGEAGP--QGDQGREGPVGVPGDPGEAGPIGPKGY 477 PG G GE G G PG +GP G PG GP +G +G GP G PG PG GP GP G Sbjct: 1215 NPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGL 1274 Query: 478 ------RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN----GTEGFPGFPGY 527 +G++G PG G G PG G G PGL G G G G G G PGFPG Sbjct: 1275 PGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGM 1334 Query: 528 PGNRGAPGINGTKGYPGLKGDEGEAGDPGDD------NNDIAPRGV---KGAKGYRGPEG 578 G G PG G +G PGL G G G PG D P G+ G KG GP+G Sbjct: 1335 KGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQG 1394 Query: 579 PQGPPGHQGPPG 590 PQG PG GPPG Sbjct: 1395 PQGLPGPTGPPG 1406 Score = 286 bits (733), Expect = 5e-77 Identities = 167/351 (47%), Positives = 185/351 (52%), Gaps = 28/351 (7%) Query: 257 GPPGLR--GDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314 GPPGL G PG G G PG PG G G PG PG G G+ G KGE G G G G Sbjct: 849 GPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPG 908 Query: 315 PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGS---PGFDGIQGPPGPKGDPGAFGLKG 371 P G G G G+ G DG++G+ G PG G KGS P G+ GPPGP DP G KG Sbjct: 909 PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEP---GLPGPPGPM-DPNLLGSKG 964 Query: 372 EKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERG 431 EKGEPG G PG SGP G +G PG+PG PG G+ G G PGP G PG G PG G Sbjct: 965 EKGEPGL---PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIG 1021 Query: 432 PRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE-----GPPGS 486 P PG +G GD G GPQG +G GP GVPG PG G G KG +GD G PG Sbjct: 1022 P---PGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGL 1078 Query: 487 EGARGAPGPAGPPGDPGLMGERGEDG-------PAGNGTEGFPGFPGYPGNRGAPGINGT 539 G +G PG G PG+PG+ G G+ G P G G PGFPG PG G GI+G Sbjct: 1079 PGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGP 1138 Query: 540 KGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G PGL G+ G G G P G KG G G GP G G G PG Sbjct: 1139 PGNPGLPGEPGPVGGGGHPGQP-GPPGEKGKPGQDGIPGPAGQKGEPGQPG 1188 Score = 281 bits (720), Expect = 2e-75 Identities = 167/374 (44%), Positives = 193/374 (51%), Gaps = 46/374 (12%) Query: 252 CQPARGPPGLRGDPGFEGERGKPGLPGEKGEA-------------GDPGRPGDLGPVGYQ 298 C+P GPPG G PG +G +G+ G+ G+KG+ G PG PG GP G Sbjct: 451 CEP--GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSL 508 Query: 299 GMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMG-------------------Y 339 G G+KG +G+ G+ GPKG G G G G G KGE G Sbjct: 509 GFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGA 568 Query: 340 PGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE 399 PGLPG G+PG DG+ G PGPKG+PG KGE+G PG G G PG+ GP G G G Sbjct: 569 PGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GP 627 Query: 400 PGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPR-GTPGTRGPRGDPGEAGPQGDQGREG 458 PGP GEKG G GNPG G PG +G PG+ + G PG G G G+ G GD G G Sbjct: 628 PGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPG 687 Query: 459 PVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NG 517 G+PG PG G G G G GPPG +G G PGP G PG PG +G G GP G G Sbjct: 688 QPGLPGIPGSKGEPGIPGI-GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746 Query: 518 TEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPE 577 +G PGF PG G PG+ G KG G KGD G G PG P G G G GP+ Sbjct: 747 PKGEPGF-ALPGPPGPPGLPGFKGALGPKGDRGFPGPPG-------PPGRTGLDGLPGPK 798 Query: 578 GPQGPPGHQGPPGP 591 G GP G GP GP Sbjct: 799 GDVGPNGQPGPMGP 812 Score = 281 bits (720), Expect = 2e-75 Identities = 170/400 (42%), Positives = 199/400 (49%), Gaps = 71/400 (17%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 +G PGL G PG G +G GLPG+ G+ G G+PG GP G KG G G+ G GP Sbjct: 966 KGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGP---PGPKGNPGLPGQPGLIGP 1022 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFD--------------GIQGPPGPK 361 G KG G G G GV+G G G+PG GSPG G+ G PGPK Sbjct: 1023 PGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPK 1082 Query: 362 GDPGA------FGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP 415 G+PG G+KG G+PG G G PG+ G G G PG PGPPG KG +G GNP Sbjct: 1083 GEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNP 1142 Query: 416 GPDGAPGERGG---PGERGPRGTPGTRGPRGDPGEAGPQGD-----------------QG 455 G G PG GG PG+ GP G G G G PG AG +G+ G Sbjct: 1143 GLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSG 1202 Query: 456 REGPVGVPGDPGEAGPIGPK---------GYRGDEGPPGS-----EGARGAPGPAGPPGD 501 ++G G+PG PG G GPK G +G GPPGS EG +G PGP GPPG Sbjct: 1203 QKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGR 1262 Query: 502 PGLMGERGEDGPAGN----------GTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGE 551 PGL G G G GN G G PG PG G++G PG+ G G PGL G +G+ Sbjct: 1263 PGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGD 1322 Query: 552 AGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G PG G+KG G G GP+G PG GPPGP Sbjct: 1323 PGLPGVPGFP----GMKGPSGVPGSAGPEGEPGLIGPPGP 1358 Score = 281 bits (718), Expect = 3e-75 Identities = 166/365 (45%), Positives = 185/365 (50%), Gaps = 52/365 (14%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPG---DLGPVG------YQGMKGEKGSR 307 G PG +G PG G G PG PG KG +G PG PG + GPVG G GEKG Sbjct: 1110 GTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKP 1169 Query: 308 GEKGSRGPKGYKGEKGKRG--------IDGVDGVKGEMGYPGLPGCKGSPG--------- 350 G+ G GP G KGE G+ G + G+ G KG+ G PG+PG G PG Sbjct: 1170 GQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHG 1229 Query: 351 FDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAG 410 F G+QGPPGP G PG L+G KG PG G GRPG GP G G PG G GEKG G Sbjct: 1230 FPGVQGPPGPPGSPGP-ALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPG 1288 Query: 411 DEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAG 470 G PG G G++G PG +G G PG G +GDPG G G G +GP GVPG AG Sbjct: 1289 QPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGS---AG 1345 Query: 471 PIGPKGYRGDEGPPGSEGARGAP----GPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPG 526 P G G G GPPG G G G AGPPG PG G +G GP G G Sbjct: 1346 PEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGP--------QG 1397 Query: 527 YPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQ 586 PG G PG G G PG G G GDPG + G G RG +GP GP G Q Sbjct: 1398 LPGPTGPPGDPGRNGLPGFDGAGGRKGDPG----------LPGQPGTRGLDGPPGPDGLQ 1447 Query: 587 GPPGP 591 GPPGP Sbjct: 1448 GPPGP 1452 Score = 278 bits (710), Expect = 2e-74 Identities = 163/379 (43%), Positives = 195/379 (51%), Gaps = 47/379 (12%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPG--RPGDLGPVGYQGMKGEKGSRGE----- 309 G GL GDPG G+ G PG+PG KGE G PG PG GP G+ G+ G G+ G Sbjct: 675 GDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIG 734 Query: 310 -KGSRGPKGYKGEKGKRGI--------------DGVDGVKGEMGYPGLPGCKGSPGFDGI 354 +G GP G+ G KG+ G G G KG+ G+PG PG G G DG+ Sbjct: 735 LEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGL 794 Query: 355 QGP---------PGPKGDPG--AFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPG-- 401 GP PGP G PG G++G G PG G G+PG G G++G PG PG Sbjct: 795 PGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLD 854 Query: 402 ---PPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREG 458 PPGE+G G G PGP G PG G PG+ G G PGT+G G G GP G G G Sbjct: 855 VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPG 914 Query: 459 PVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG--- 515 GVPG G+ G G G G G GS+G G PGP GP DP L+G +GE G G Sbjct: 915 RSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPM-DPNLLGSKGEKGEPGLPG 973 Query: 516 -NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGA---K 571 G G G+ G PG+ G PG++G G PG G +G G PG I P G+KG Sbjct: 974 IPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGL-IGPPGLKGTIGDM 1032 Query: 572 GYRGPEGPQGPPGHQGPPG 590 G+ GP+G +GPPG G PG Sbjct: 1033 GFPGPQGVEGPPGPSGVPG 1051 Score = 274 bits (701), Expect = 3e-73 Identities = 161/375 (42%), Positives = 189/375 (50%), Gaps = 43/375 (11%) Query: 255 ARGPPGLR---GDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGM----------- 300 A GP G R G PG G G GLPG KG+ G G+PG +GP G G+ Sbjct: 770 ALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI 829 Query: 301 ------KGEKGSRGEKGSRGPKGY-----KGEKGKRGIDGVDGVKGEMGYPGLPGCKGSP 349 G G GEKG GP G GE+G GI G G G G PGLPG G+ Sbjct: 830 PGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889 Query: 350 GFDGIQ---------GPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEP 400 GF G + GPPGP G PG G+ G KG+ G G+ G PG +G G +G+PG P Sbjct: 890 GFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLP 949 Query: 401 GPPGEK-----GEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQG 455 GPPG G G++G PG G PG G G +G G PG G G PG GP G +G Sbjct: 950 GPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKG 1009 Query: 456 REGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG 515 G+PG PG GP G KG GD G PG +G G PGP+G PG PG G G+ G G Sbjct: 1010 NP---GLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG 1066 Query: 516 NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRG 575 + G PG PG +G PG+ G G PG+KG G+ G PG A +G G G+ G Sbjct: 1067 DPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGA-KGQPGLPGFPG 1125 Query: 576 PEGPQGPPGHQGPPG 590 GP GP G GPPG Sbjct: 1126 TPGPPGPKGISGPPG 1140 Score = 271 bits (694), Expect = 2e-72 Identities = 170/409 (41%), Positives = 194/409 (47%), Gaps = 75/409 (18%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RG PGL G PG G G G PG +G+ GD G PG GP G +G G G G G G Sbjct: 50 RGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGM 109 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFG------- 368 G+ G G +GI G +G KGE G+PG SPGF G+QGPPGP G PG G Sbjct: 110 PGHDGAPGPQGIPGCNGTKGERGFPG------SPGFPGLQGPPGPPGIPGMKGEPGSIIM 163 Query: 369 --LKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPP----------------------- 403 L G KG PG G G G GP+G G G PGPP Sbjct: 164 SSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQ 223 Query: 404 ---GEKGEAGDEGNPGPDG-------------APGERGGPGERGPRGTPGTRGPRGDP-G 446 GEKGE G +G PGP G G++G PG+RGP G PG RGP G P G Sbjct: 224 GPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGG 283 Query: 447 EAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD---EGPPGSEGARGAPGPAGPPGDPG 503 E G +G+QG G G PG GE G G G GD G PG +G +G G GPPG PG Sbjct: 284 EKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPG 343 Query: 504 L----------MGERGEDG----PAGNGTEGFPGFPGYPGNRGAPG--INGTKGYPGLKG 547 L +GE+G G P G GFPG G PG G PG + G G PG G Sbjct: 344 LVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPG 403 Query: 548 DEGEAGDPGDDNNDI-APRGVKGAKGYRGPEGPQGPPGHQGPPGPDECE 595 + G+ GD G I P G+ G G G GP GP G PP + CE Sbjct: 404 ERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICE 452 Score = 270 bits (689), Expect = 7e-72 Identities = 165/367 (44%), Positives = 187/367 (50%), Gaps = 31/367 (8%) Query: 254 PARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGR----------PGDLGPVGYQGMKGE 303 P GPPG G+ G +G G PG PG G GDPG+ PG+ G G G+ G+ Sbjct: 623 PGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGD 682 Query: 304 KGSRGEKGSRGPKGYKGEKGKRGI--DGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361 G G+ G G G KGE G GI G G KG G PG PG G+PG G++GPPGP Sbjct: 683 PGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPP 742 Query: 362 GDPGAFGLKG--EKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGE---------KGEAG 410 G PG G G G PG G G G+ GP GD G PG PGPPG KG+ G Sbjct: 743 GFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVG 802 Query: 411 DEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVG--VPGDPGE 468 G PGP G PG G G +GP G PG GP G PG G G++G GP G VPG PGE Sbjct: 803 PNGQPGPMGPPG-LPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGE 861 Query: 469 AGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGF 524 G G G G GPPGS G G G +G PG G MG G GP G G G PG Sbjct: 862 RGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGL 921 Query: 525 PGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGD-DNNDIAPRGVKGAKGYRGPEGPQGPP 583 G G +G PG+ G G G KG+ G G PG D N + +G KG G G G GP Sbjct: 922 KGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPK 981 Query: 584 GHQGPPG 590 G+QG PG Sbjct: 982 GYQGLPG 988 Score = 268 bits (686), Expect = 1e-71 Identities = 168/395 (42%), Positives = 196/395 (49%), Gaps = 55/395 (13%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG-- 314 G PGL G PG G+ G PGLPG KGE G G+ GP G G+ G G+ G G G Sbjct: 567 GAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFG 626 Query: 315 PKGYKGEKGKRGI------DGVDGVKGEMGY----PGLPGCKGSPGFDG---IQGPPGPK 361 P G GEKG +G+ G+ G KG+ G PG PG G+PG DG + G PG Sbjct: 627 PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP 686 Query: 362 GDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAP 421 G PG G+ G KGEPG G G PG GP G G PG PG PG G G EG PGP G P Sbjct: 687 GQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFP 745 Query: 422 GERGGPG-----ERGPRGTPGTRG---PRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIG 473 G +G PG GP G PG +G P+GD G GP G GR G G+PG G+ GP G Sbjct: 746 GPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNG 805 Query: 474 PKGYRGDEGPPG-----SEGARGAPGPAGPPGDPGLMGERGEDGPAG---------NGTE 519 G G G PG G G PGP G PG G+ GE+G+ GP G G+ Sbjct: 806 QPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSP 865 Query: 520 GFPGFPGY---PGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN--------------NDI 562 G PG PG PG+ G PG G G+PG KG+ G G PG D Sbjct: 866 GIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDD 925 Query: 563 APRGVKGAKGYRGPEGPQGPPGHQGPPGPDECEIL 597 +G G G G +G +G PG GPPGP + +L Sbjct: 926 GLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960 Score = 268 bits (685), Expect = 2e-71 Identities = 168/384 (43%), Positives = 194/384 (50%), Gaps = 52/384 (13%) Query: 257 GPPGLRGDPGFEGERGK------------PGLPGEKGEAGDPGRPGDLGPVGYQGMKGEK 304 GPPG G PG +GE+G+ PG PG G G G PGD+ + + GMKG+K Sbjct: 503 GPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDI--LTFPGMKGDK 560 Query: 305 GSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMG---YPGLPGCKGSPGFDGIQGPPGPK 361 G G G+ G G G G+ G+ G+ G KGE G + G G G+PG G+ G GP Sbjct: 561 GELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPM 620 Query: 362 GDP--GAFGLKGEKGEPGADGEAGRPGSSGPSGDEG----QPGEPGPPGEKGEAGDEGNP 415 G P G G GEKG G G G+PG GP GD G QPG+PG PG G GD G P Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLP 680 Query: 416 GPDGAPGER-----------------GGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREG 458 G G PG+ G PG GP+G PG GP G PG G G +G G Sbjct: 681 GDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPG 740 Query: 459 PVGVPGDPGE-----AGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGD---PGLMGERGE 510 P G PG GE GP GP G G +G G +G RG PGP GPPG GL G +G+ Sbjct: 741 PPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGD 800 Query: 511 DGPAGN-GTEGFPGFP--GYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDI-APRG 566 GP G G G PG P G G G PGI G G PGL G GE GDPG D+ P G Sbjct: 801 VGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPG 860 Query: 567 VKGAKGYRGPEGPQGPPGHQGPPG 590 +G+ G G GP GPPG G PG Sbjct: 861 ERGSPGIPGAPGPIGPPGSPGLPG 884 Score = 266 bits (679), Expect = 1e-70 Identities = 178/436 (40%), Positives = 208/436 (47%), Gaps = 108/436 (24%) Query: 257 GPPGLRGDPG---FEGERGKPGLPGEKGEAGDPGRPGDLGPVG--YQGMKGEKGSRGEKG 311 GPPG++G PG G G PG PG G G PG PG G +G +QG KGEKG +G +G Sbjct: 177 GPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQG 236 Query: 312 SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP----KGDPGAF 367 GP G E+ KR ID V+ + G GLPG +G PG GI+GPPGP KG+ G Sbjct: 237 PPGPPGQISEQ-KRPID----VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQ 291 Query: 368 GLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA------- 420 G G++G+PG DGE G+PG G GD G PGEPG GEKG+ GD G PGP G Sbjct: 292 GEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGT 351 Query: 421 ------------------PGERGGPGERGPRGTPGTRG--------PRGDPGEAGPQGDQ 454 GERG PG +GP G PG G P G PGE G +GD+ Sbjct: 352 GITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDE 411 Query: 455 GREG-----PVGVPGDPGEAGPIGPKGYRGDEGPPGSEGAR-GAPGPAGPPGDPGLMGER 508 G G P G+ G PG G GP G G PP E G PGP G PGD GL GE+ Sbjct: 412 GPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQ 471 Query: 509 GEDGPAGN--------------------------GTEGFP---------------GFPGY 527 G G G+ G+ GFP G PG Sbjct: 472 GVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI 531 Query: 528 PGNRGAPGINGTKG-------YPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQ 580 PG GAPG G+KG +PG+KGD+GE G PG P G G G G GP+ Sbjct: 532 PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLP-GTPGQDGLPGLPGPK 590 Query: 581 GPP------GHQGPPG 590 G P G +GPPG Sbjct: 591 GEPGGITFKGERGPPG 606 Score = 265 bits (676), Expect = 2e-70 Identities = 165/364 (45%), Positives = 186/364 (51%), Gaps = 39/364 (10%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG--S 312 A G PGL G P G+ G PGLPG KGE G G+ GP G G+ G G+ G G Sbjct: 568 APGLPGLPGTP---GQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG 624 Query: 313 RGPKGYKGEKGKRGI------DGVDGVKGEMG----YPGLPGCKGSPGFD---GIQGPPG 359 GP G GEKG +G+ G+ G KG+ G PG PG G+PG D G+ G PG Sbjct: 625 FGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPG 684 Query: 360 PKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDG 419 G PG G+ G KGEPG G G PG GP G G PG PG PG G G EG PGP G Sbjct: 685 LPGQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPG 743 Query: 420 APGERGG-----PGERGPRGTPGTR---GPRGDPGEAGPQGDQGREGPVGVPGDPGEAGP 471 PG +G PG GP G PG + GP+GD G GP G GR G G+PG G+ GP Sbjct: 744 FPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGP 803 Query: 472 IGPKGYRGDEGPP-----GSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPG 526 G G G G P G G G PGP G PG G+ GE+G+ GP G G PG G Sbjct: 804 NGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERG 863 Query: 527 YPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQ 586 PG GAPG G G PGL G G +G PG +G G G GP GP G PG Sbjct: 864 SPGIPGAPGPIGPPGSPGLPGKAGASGFPG-------TKGEMGMMGPPGPPGPLGIPGRS 916 Query: 587 GPPG 590 G PG Sbjct: 917 GVPG 920 Score = 261 bits (666), Expect = 3e-69 Identities = 176/457 (38%), Positives = 203/457 (44%), Gaps = 124/457 (27%) Query: 257 GPPGLRGDPG-------------FEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGE 303 GPPG+RG PG G+RGKPG GE G+ G PG PGD G G G GE Sbjct: 270 GPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGE 329 Query: 304 KGSRGEKGSRGPKGYK----------GEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDG 353 KG +G+ G GP G GEKG G+ G+ G KGE G+PG+ G G PG G Sbjct: 330 KGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG 389 Query: 354 --IQGPPGPKGDPGAFGLKGEKGEPGA--------DGEAGRPGSSGPSGDEG-------- 395 + GPPGP G PG G KG++G PG DG+ G PG GP G G Sbjct: 390 AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449 Query: 396 --QPGEPGPPG---------EKGEAGDEGN-------------------PGPDGAPGERG 425 +PG PGPPG E+G GD+G+ PG G PG G Sbjct: 450 ICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLG 509 Query: 426 GPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGD----------PGEAGPIGPK 475 PG++G +G G GP+G PG G G G G G PGD GE G G Sbjct: 510 FPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAP 569 Query: 476 GYRGDEGPPGSEGARGAPGPAG------------PPGDPGLMGERGEDGPAG-------- 515 G G G PG +G G PGP G PPG+PGL G G GP G Sbjct: 570 GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG 629 Query: 516 -------NGTEGFPGFPGYPGNRGAPGIN-------GTKGYPGLKGDEGEAGDPGDDNND 561 G G PG PG PG +G PG G G PG GD G GDPG Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689 Query: 562 IAPRGVKGAK--------GYRGPEGPQGPPGHQGPPG 590 P G+ G+K G GP GP+G PG GPPG Sbjct: 690 GLP-GIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPG 725 Score = 220 bits (561), Expect = 5e-57 Identities = 138/348 (39%), Positives = 156/348 (44%), Gaps = 86/348 (24%) Query: 329 GVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD------------------------- 363 G+ G KGE G+PGL G G PGF G +GPPGP+G Sbjct: 42 GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP 101 Query: 364 --------------------PGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGP- 402 PG G KGE+G PG+ G G G GP G G GEPG Sbjct: 102 GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSI 161 Query: 403 -----PGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGR- 456 PG KG G G PG G PG G PG GP G PG GP G PG GP+G+ G Sbjct: 162 IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLN 221 Query: 457 -EGPVGVPGDPGEAGPIGPKG-------------YRGDEGPPGSEGARGAPGPAGPPGDP 502 +GP G G+ G GP GP G +GD+G PG G G PG GPPG P Sbjct: 222 FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPP 281 Query: 503 -GLMGERGEDG-------PAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGD 554 G GE+GE G P +G G PG PG PG+ G PG G G G KGD G G Sbjct: 282 GGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGP 341 Query: 555 PG------------DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 PG + +I G+ G KG RG G QGPPG GPPG Sbjct: 342 PGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG 389 Score = 220 bits (560), Expect = 6e-57 Identities = 127/275 (46%), Positives = 148/275 (53%), Gaps = 36/275 (13%) Query: 253 QPARGPPGLRGDPGFEGERGK---------PGLPGEKGEAGDPGRPGDLGPVGYQG---- 299 QP G PG G PG G++G PGLPG KGE G G PG GP G G Sbjct: 1186 QPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP 1245 Query: 300 -MKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPP 358 ++G KG+ G +G G G G +G G+ G G+KGE G PG PG G PG G QGPP Sbjct: 1246 ALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPP 1305 Query: 359 GPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPS------GDEGQP---GEPGPPGEKGEA 409 G +G+PG GL G KG+PG G G PG GPS G EG+P G PGPPG G + Sbjct: 1306 GLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPS 1365 Query: 410 -------GDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGV 462 GD G PG G PG +G PG +GP+G PG GP GDPG G G G G G Sbjct: 1366 GQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGD 1425 Query: 463 PGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAG 497 PG PG+ G RG +GPPG +G +G PGP G Sbjct: 1426 PGLPGQPGT------RGLDGPPGPDGLQGPPGPPG 1454 Score = 161 bits (408), Expect = 3e-39 Identities = 103/251 (41%), Positives = 115/251 (45%), Gaps = 36/251 (14%) Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436 G EA P G G GE+G G EG+PG G PG G PG RG +G Sbjct: 21 GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80 Query: 437 GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY------RGDEGPPGSEGAR 490 G GP G G GP G G G G+PG PG G GP+G +G+ G PGS G Sbjct: 81 GIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP 140 Query: 491 GAPGPAGPPGDPGLMGERGE------DGPAGN-GTEGFPGFPGYPGNRGAPGINGTKGYP 543 G GP GPPG PG+ GE G GP GN G G PG G PG G PG G G P Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPP 200 Query: 544 GLKGDEGEAGDPGDDN----NDIAPRGVKGAKGYRGPEGP-------------------Q 580 GL G G G PG N P+G KG +G +GP GP Q Sbjct: 201 GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQ 260 Query: 581 GPPGHQGPPGP 591 G PG +GPPGP Sbjct: 261 GLPGDRGPPGP 271 Score = 52.0 bits (123), Expect = 3e-06 Identities = 30/75 (40%), Positives = 36/75 (48%), Gaps = 3/75 (4%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 +G PG +G G G G PG PG G PG G G G G+ G+ G+RG G GP Sbjct: 1387 KGLPGPQGPQGLPGPTGPPGDPGRNGL---PGFDGAGGRKGDPGLPGQPGTRGLDGPPGP 1443 Query: 316 KGYKGEKGKRGIDGV 330 G +G G G V Sbjct: 1444 DGLQGPPGPPGTSSV 1458 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 292 bits (748), Expect = 1e-78 Identities = 175/377 (46%), Positives = 199/377 (52%), Gaps = 39/377 (10%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 GPPG +G+PG G+ G G PG KG GD G PG P G +G G G G+ GS G Sbjct: 1003 GPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG---PQGVEGPPGPSGVPGQPGSPGLP 1059 Query: 317 GYKGEKGKRGID-----GVDGVKGEMG---YPGLPGCKGS---PGFDGIQGPPGPKGDPG 365 G KG+KG GI G+ G KGE G YPG PG KGS PG G+ G PG KG PG Sbjct: 1060 GQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPG 1119 Query: 366 AFGLKGEKGEPGADGEAGRPGSSG------PSGDEGQPGEPGPPGEKGEAGDEGNPGPDG 419 G G G PG G +G PG+ G P G G PG+PGPPGEKG+ G +G PGP G Sbjct: 1120 LPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG 1179 Query: 420 APGERGGPG--ERGPRGTPGTRGPRGD---------PGEAGPQGDQGREGPVGV---PGD 465 GE G PG GP G PG G +GD PG GP+G+ G G GV PG Sbjct: 1180 QKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGP 1239 Query: 466 PGEAGPI--GPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFP 522 PG GP GPKG G +GPPG G G G GP G PGL G G G GN G G P Sbjct: 1240 PGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLP 1299 Query: 523 GFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN--NDIAPRGVKGAKGYRGPEGPQ 580 G PG G++G PG+ G G PGL G +G+ G PG P GV G+ G G G Sbjct: 1300 GLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLI 1359 Query: 581 GPPGHQGPPGPDECEIL 597 GPPG G PGP I+ Sbjct: 1360 GPPGPPGLPGPSGQSII 1376 Score = 290 bits (742), Expect = 5e-78 Identities = 163/346 (47%), Positives = 189/346 (54%), Gaps = 26/346 (7%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312 Q GPPG G P G+ G PGLPG+KG+ GDPG + +G G+ G KG G G Sbjct: 1038 QGVEGPPGPSGVP---GQPGSPGLPGQKGDKGDPG----ISSIGLPGLPGPKGEPGLPGY 1090 Query: 313 RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372 G G KG G G+ G+ G G G PGLPG G+P GPPGPKG G G G Sbjct: 1091 PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTP------GPPGPKGISGPPGNPGL 1144 Query: 373 KGEPGADGEAGRPGSSGPSGDEGQPGE---PGPPGEKGEAGDE--GNPGPDGAPGERGGP 427 GEPG G G PG GP G++G+PG+ PGP G+KGE G GNPGP G PG G Sbjct: 1145 PGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQK 1204 Query: 428 GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEA--GPIGPKGYRGDEGPPG 485 G+ G G PG G G GE G G G +GP G PG PG A GP G G +G G PG Sbjct: 1205 GDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPG 1264 Query: 486 SEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGL 545 G +G PGP GPPG PG G +GE G G G PG PG G++G PG+ G G PGL Sbjct: 1265 PTGFQGLPGPEGPPGLPGNGGIKGEKG--NPGQPGLPGLPGLKGDQGPPGLQGNPGRPGL 1322 Query: 546 KGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G +G+ G PG G+KG G G GP+G PG GPPGP Sbjct: 1323 NGMKGDPGLPGVPGFP----GMKGPSGVPGSAGPEGEPGLIGPPGP 1364 Score = 289 bits (740), Expect = 8e-78 Identities = 173/382 (45%), Positives = 194/382 (50%), Gaps = 51/382 (13%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMK------------- 301 A GP G G PG G+ G G PG KGE G G PG GP+G G Sbjct: 870 APGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQG 929 Query: 302 --------GEKGSRGEKGSRGPK--------GYKGEKGKRGIDGVDGVKGEMGYPGLPGC 345 GEKGS+GE G GP G KGEKG+ G+ G+ GV G GY GLPG Sbjct: 930 QPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD 989 Query: 346 KGSPGFD---GIQGPPGPKGDP---------GAFGLKGEKGEPGADGEAGRPGSSGPSGD 393 G PG G+ GPPGPKG+P G GLKG G+ G G G G GPSG Sbjct: 990 PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049 Query: 394 EGQPGEPGPPGEKGEAGDEG--NPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQ 451 GQPG PG PG+KG+ GD G + G G PG +G PG G G PG +G GDPG G Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLP 1109 Query: 452 GDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGED 511 G G +G G+PG PG GP GPKG GPPG+ G G PGP G G PG G GE Sbjct: 1110 GTPGAKGQPGLPGFPGTPGPPGPKGI---SGPPGNPGLPGEPGPVGGGGHPGQPGPPGEK 1166 Query: 512 GPAGNGTEGFPGFPGYPGNRGAPGIN--GTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKG 569 G G +G PG G G G PG G G PGL G +G+ G PG N P G KG Sbjct: 1167 GKPGQ--DGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLP-GPKG 1223 Query: 570 AKGYRGPEGPQGPPGHQGPPGP 591 G+ G G QGPPG G PGP Sbjct: 1224 EPGFHGFPGVQGPPGPPGSPGP 1245 Score = 286 bits (733), Expect = 5e-77 Identities = 167/351 (47%), Positives = 185/351 (52%), Gaps = 28/351 (7%) Query: 257 GPPGLR--GDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314 GPPGL G PG G G PG PG G G PG PG G G+ G KGE G G G G Sbjct: 849 GPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPG 908 Query: 315 PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGS---PGFDGIQGPPGPKGDPGAFGLKG 371 P G G G G+ G DG++G+ G PG G KGS P G+ GPPGP DP G KG Sbjct: 909 PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEP---GLPGPPGPM-DPNLLGSKG 964 Query: 372 EKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERG 431 EKGEPG G PG SGP G +G PG+PG PG G+ G G PGP G PG G PG G Sbjct: 965 EKGEPGL---PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIG 1021 Query: 432 PRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE-----GPPGS 486 P PG +G GD G GPQG +G GP GVPG PG G G KG +GD G PG Sbjct: 1022 P---PGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGL 1078 Query: 487 EGARGAPGPAGPPGDPGLMGERGEDG-------PAGNGTEGFPGFPGYPGNRGAPGINGT 539 G +G PG G PG+PG+ G G+ G P G G PGFPG PG G GI+G Sbjct: 1079 PGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGP 1138 Query: 540 KGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G PGL G+ G G G P G KG G G GP G G G PG Sbjct: 1139 PGNPGLPGEPGPVGGGGHPGQP-GPPGEKGKPGQDGIPGPAGQKGEPGQPG 1188 Score = 285 bits (728), Expect = 2e-76 Identities = 167/362 (46%), Positives = 192/362 (53%), Gaps = 29/362 (8%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPV-----GYQGMKGEKGSRGEKG 311 G PGL+GD G +G+ G PG GEKG G+PG PG GP+ G +G KGE G G G Sbjct: 917 GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPG 976 Query: 312 SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD------PG 365 GPKGY+G G G G+ G G G PG G G PG G+ GPPG KG PG Sbjct: 977 VSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG 1036 Query: 366 AFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE-----PGPPGEKGEAGDEGNPGPDGA 420 G++G G G G+ G PG G GD+G PG PG PG KGE G G PG G Sbjct: 1037 PQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGI 1096 Query: 421 PGERGGPGERGPRGTPGTRGP---RGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY 477 G G PG G GTPG +G G PG GP G +G GP G PG PGE GP+G G+ Sbjct: 1097 KGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGH 1156 Query: 478 RGDEGPPGSE---GARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFPGYPGN 530 G GPPG + G G PGPAG G+PG G G GP G +G +G G PG PGN Sbjct: 1157 PGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG-FGNPGPPGLPGLSGQKGDGGLPGIPGN 1215 Query: 531 RGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 G PG G G+ G G +G G PG A G KG G +GP G GP G QG PG Sbjct: 1216 PGLPGPKGEPGFHGFPGVQGPPGPPGSPGP--ALEGPKGNPGPQGPPGRPGPTGFQGLPG 1273 Query: 591 PD 592 P+ Sbjct: 1274 PE 1275 Score = 282 bits (721), Expect = 1e-75 Identities = 168/360 (46%), Positives = 190/360 (52%), Gaps = 27/360 (7%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316 G PGL G PG G +G+PGLPG G G PG G GP G G+ GE G G G G Sbjct: 1101 GDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQP 1160 Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD------PGAFGLK 370 G GEKGK G DG+ G G+ G PG PG G+PG G+ G G KGD PG GL Sbjct: 1161 GPPGEKGKPGQDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGLPGIPGNPGLP 1219 Query: 371 GEKGEPG------ADGEAGRPGSSGPS--GDEGQPGEPGPPGEKGEAGDEGNPGPDGAPG 422 G KGEPG G G PGS GP+ G +G PG GPPG G G +G PGP+G PG Sbjct: 1220 GPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPG 1279 Query: 423 ERGGPGERGPRGTPGTRGP------RGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKG 476 G G +G +G PG G +GD G G QG+ GR G G+ GDPG G G G Sbjct: 1280 LPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPG 1339 Query: 477 YRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGI 536 +G G PGS G G PG GPPG PGL G G+ G G PG PG PG +G PG Sbjct: 1340 MKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQ-SIIIKGDAGPPGIPGQPGLKGLPGP 1398 Query: 537 NGTKGYP---GLKGDEGEAGDPGDD--NNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591 G +G P G GD G G PG D G+ G G RG +GP GP G QGPPGP Sbjct: 1399 QGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGP 1458 Score = 281 bits (720), Expect = 2e-75 Identities = 167/374 (44%), Positives = 193/374 (51%), Gaps = 46/374 (12%) Query: 252 CQPARGPPGLRGDPGFEGERGKPGLPGEKGEA-------------GDPGRPGDLGPVGYQ 298 C+P GPPG G PG +G +G+ G+ G+KG+ G PG PG GP G Sbjct: 451 CEP--GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSL 508 Query: 299 GMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMG-------------------Y 339 G G+KG +G+ G+ GPKG G G G G G KGE G Sbjct: 509 GFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGA 568 Query: 340 PGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE 399 PGLPG G+PG DG+ G PGPKG+PG KGE+G PG G G PG+ GP G G G Sbjct: 569 PGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GP 627 Query: 400 PGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPR-GTPGTRGPRGDPGEAGPQGDQGREG 458 PGP GEKG G GNPG G PG +G PG+ + G PG G G G+ G GD G G Sbjct: 628 PGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPG 687 Query: 459 PVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NG 517 G+PG PG G G G G GPPG +G G PGP G PG PG +G G GP G G Sbjct: 688 QPGLPGIPGSKGEPGIPGI-GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746 Query: 518 TEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPE 577 +G PGF PG G PG+ G KG G KGD G G PG P G G G GP+ Sbjct: 747 PKGEPGF-ALPGPPGPPGLPGFKGALGPKGDRGFPGPPG-------PPGRTGLDGLPGPK 798 Query: 578 GPQGPPGHQGPPGP 591 G GP G GP GP Sbjct: 799 GDVGPNGQPGPMGP 812 Score = 280 bits (716), Expect = 5e-75 Identities = 167/389 (42%), Positives = 194/389 (49%), Gaps = 54/389 (13%) Query: 257 GPPGLRGDPG---FEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSR 313 GP G+ G PG G+ G PGLPG+KG+ GDPG +G G G KGE G G G+ Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI-SSIGLPGLPGPKGEPGLPGYPGNP 1094 Query: 314 GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKG---DPGAFGLK 370 G KG G+ G G+ G G KG+ G PG PG G PG GI GPPG G +PG G Sbjct: 1095 GIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGG 1154 Query: 371 GEKGEPGADGEAGRPGSSG---PSGDEGQPGEPG-----PPGEKGEAGDEGN-------- 414 G G+PG GE G+PG G P+G +G+PG+PG PPG G +G +G+ Sbjct: 1155 GHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPG 1214 Query: 415 ----PGPDGAPGERGGPGERGPRGTPGTRGP--RGDPGEAGPQGDQGREGPVGVPGDPGE 468 PGP G PG G PG +GP G PG+ GP G G GPQG GR GP G G PG Sbjct: 1215 NPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGP 1274 Query: 469 AGPIGPKG---YRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN----GTEGF 521 GP G G +G++G PG G G PG G G PGL G G G G G G Sbjct: 1275 EGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGV 1334 Query: 522 PGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNN------DIAPRGVKGAKGYRG 575 PGFPG G G PG G +G PGL G G G PG D P G+ G G +G Sbjct: 1335 PGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKG 1394 Query: 576 ------------PEGPQGPPGHQGPPGPD 592 P GP G PG G PG D Sbjct: 1395 LPGPQGPQGLPGPTGPPGDPGRNGLPGFD 1423 Score = 278 bits (710), Expect = 2e-74 Identities = 163/379 (43%), Positives = 195/379 (51%), Gaps = 47/379 (12%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPG--RPGDLGPVGYQGMKGEKGSRGE----- 309 G GL GDPG G+ G PG+PG KGE G PG PG GP G+ G+ G G+ G Sbjct: 675 GDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIG 734 Query: 310 -KGSRGPKGYKGEKGKRGI--------------DGVDGVKGEMGYPGLPGCKGSPGFDGI 354 +G GP G+ G KG+ G G G KG+ G+PG PG G G DG+ Sbjct: 735 LEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGL 794 Query: 355 QGP---------PGPKGDPG--AFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPG-- 401 GP PGP G PG G++G G PG G G+PG G G++G PG PG Sbjct: 795 PGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLD 854 Query: 402 ---PPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREG 458 PPGE+G G G PGP G PG G PG+ G G PGT+G G G GP G G G Sbjct: 855 VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPG 914 Query: 459 PVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG--- 515 GVPG G+ G G G G G GS+G G PGP GP DP L+G +GE G G Sbjct: 915 RSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPM-DPNLLGSKGEKGEPGLPG 973 Query: 516 -NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGA---K 571 G G G+ G PG+ G PG++G G PG G +G G PG I P G+KG Sbjct: 974 IPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGL-IGPPGLKGTIGDM 1032 Query: 572 GYRGPEGPQGPPGHQGPPG 590 G+ GP+G +GPPG G PG Sbjct: 1033 GFPGPQGVEGPPGPSGVPG 1051 Score = 274 bits (701), Expect = 3e-73 Identities = 161/375 (42%), Positives = 189/375 (50%), Gaps = 43/375 (11%) Query: 255 ARGPPGLR---GDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGM----------- 300 A GP G R G PG G G GLPG KG+ G G+PG +GP G G+ Sbjct: 770 ALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI 829 Query: 301 ------KGEKGSRGEKGSRGPKGY-----KGEKGKRGIDGVDGVKGEMGYPGLPGCKGSP 349 G G GEKG GP G GE+G GI G G G G PGLPG G+ Sbjct: 830 PGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889 Query: 350 GFDGIQ---------GPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEP 400 GF G + GPPGP G PG G+ G KG+ G G+ G PG +G G +G+PG P Sbjct: 890 GFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLP 949 Query: 401 GPPGEK-----GEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQG 455 GPPG G G++G PG G PG G G +G G PG G G PG GP G +G Sbjct: 950 GPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKG 1009 Query: 456 REGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG 515 G+PG PG GP G KG GD G PG +G G PGP+G PG PG G G+ G G Sbjct: 1010 NP---GLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG 1066 Query: 516 NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRG 575 + G PG PG +G PG+ G G PG+KG G+ G PG A +G G G+ G Sbjct: 1067 DPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGA-KGQPGLPGFPG 1125 Query: 576 PEGPQGPPGHQGPPG 590 GP GP G GPPG Sbjct: 1126 TPGPPGPKGISGPPG 1140 Score = 271 bits (694), Expect = 2e-72 Identities = 170/409 (41%), Positives = 194/409 (47%), Gaps = 75/409 (18%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 RG PGL G PG G G G PG +G+ GD G PG GP G +G G G G G G Sbjct: 50 RGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGM 109 Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFG------- 368 G+ G G +GI G +G KGE G+PG SPGF G+QGPPGP G PG G Sbjct: 110 PGHDGAPGPQGIPGCNGTKGERGFPG------SPGFPGLQGPPGPPGIPGMKGEPGSIIM 163 Query: 369 --LKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPP----------------------- 403 L G KG PG G G G GP+G G G PGPP Sbjct: 164 SSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQ 223 Query: 404 ---GEKGEAGDEGNPGPDG-------------APGERGGPGERGPRGTPGTRGPRGDP-G 446 GEKGE G +G PGP G G++G PG+RGP G PG RGP G P G Sbjct: 224 GPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGG 283 Query: 447 EAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD---EGPPGSEGARGAPGPAGPPGDPG 503 E G +G+QG G G PG GE G G G GD G PG +G +G G GPPG PG Sbjct: 284 EKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPG 343 Query: 504 L----------MGERGEDG----PAGNGTEGFPGFPGYPGNRGAPG--INGTKGYPGLKG 547 L +GE+G G P G GFPG G PG G PG + G G PG G Sbjct: 344 LVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPG 403 Query: 548 DEGEAGDPGDDNNDI-APRGVKGAKGYRGPEGPQGPPGHQGPPGPDECE 595 + G+ GD G I P G+ G G G GP GP G PP + CE Sbjct: 404 ERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICE 452 Score = 270 bits (689), Expect = 7e-72 Identities = 165/367 (44%), Positives = 187/367 (50%), Gaps = 31/367 (8%) Query: 254 PARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGR----------PGDLGPVGYQGMKGE 303 P GPPG G+ G +G G PG PG G GDPG+ PG+ G G G+ G+ Sbjct: 623 PGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGD 682 Query: 304 KGSRGEKGSRGPKGYKGEKGKRGI--DGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361 G G+ G G G KGE G GI G G KG G PG PG G+PG G++GPPGP Sbjct: 683 PGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPP 742 Query: 362 GDPGAFGLKG--EKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGE---------KGEAG 410 G PG G G G PG G G G+ GP GD G PG PGPPG KG+ G Sbjct: 743 GFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVG 802 Query: 411 DEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVG--VPGDPGE 468 G PGP G PG G G +GP G PG GP G PG G G++G GP G VPG PGE Sbjct: 803 PNGQPGPMGPPG-LPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGE 861 Query: 469 AGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGF 524 G G G G GPPGS G G G +G PG G MG G GP G G G PG Sbjct: 862 RGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGL 921 Query: 525 PGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGD-DNNDIAPRGVKGAKGYRGPEGPQGPP 583 G G +G PG+ G G G KG+ G G PG D N + +G KG G G G GP Sbjct: 922 KGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPK 981 Query: 584 GHQGPPG 590 G+QG PG Sbjct: 982 GYQGLPG 988 Score = 268 bits (686), Expect = 1e-71 Identities = 168/395 (42%), Positives = 196/395 (49%), Gaps = 55/395 (13%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG-- 314 G PGL G PG G+ G PGLPG KGE G G+ GP G G+ G G+ G G G Sbjct: 567 GAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFG 626 Query: 315 PKGYKGEKGKRGI------DGVDGVKGEMGY----PGLPGCKGSPGFDG---IQGPPGPK 361 P G GEKG +G+ G+ G KG+ G PG PG G+PG DG + G PG Sbjct: 627 PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP 686 Query: 362 GDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAP 421 G PG G+ G KGEPG G G PG GP G G PG PG PG G G EG PGP G P Sbjct: 687 GQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFP 745 Query: 422 GERGGPG-----ERGPRGTPGTRG---PRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIG 473 G +G PG GP G PG +G P+GD G GP G GR G G+PG G+ GP G Sbjct: 746 GPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNG 805 Query: 474 PKGYRGDEGPPG-----SEGARGAPGPAGPPGDPGLMGERGEDGPAG---------NGTE 519 G G G PG G G PGP G PG G+ GE+G+ GP G G+ Sbjct: 806 QPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSP 865 Query: 520 GFPGFPGY---PGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN--------------NDI 562 G PG PG PG+ G PG G G+PG KG+ G G PG D Sbjct: 866 GIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDD 925 Query: 563 APRGVKGAKGYRGPEGPQGPPGHQGPPGPDECEIL 597 +G G G G +G +G PG GPPGP + +L Sbjct: 926 GLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960 Score = 268 bits (685), Expect = 2e-71 Identities = 168/384 (43%), Positives = 194/384 (50%), Gaps = 52/384 (13%) Query: 257 GPPGLRGDPGFEGERGK------------PGLPGEKGEAGDPGRPGDLGPVGYQGMKGEK 304 GPPG G PG +GE+G+ PG PG G G G PGD+ + + GMKG+K Sbjct: 503 GPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDI--LTFPGMKGDK 560 Query: 305 GSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMG---YPGLPGCKGSPGFDGIQGPPGPK 361 G G G+ G G G G+ G+ G+ G KGE G + G G G+PG G+ G GP Sbjct: 561 GELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPM 620 Query: 362 GDP--GAFGLKGEKGEPGADGEAGRPGSSGPSGDEG----QPGEPGPPGEKGEAGDEGNP 415 G P G G GEKG G G G+PG GP GD G QPG+PG PG G GD G P Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLP 680 Query: 416 GPDGAPGER-----------------GGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREG 458 G G PG+ G PG GP+G PG GP G PG G G +G G Sbjct: 681 GDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPG 740 Query: 459 PVGVPGDPGE-----AGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGD---PGLMGERGE 510 P G PG GE GP GP G G +G G +G RG PGP GPPG GL G +G+ Sbjct: 741 PPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGD 800 Query: 511 DGPAGN-GTEGFPGFP--GYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDI-APRG 566 GP G G G PG P G G G PGI G G PGL G GE GDPG D+ P G Sbjct: 801 VGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPG 860 Query: 567 VKGAKGYRGPEGPQGPPGHQGPPG 590 +G+ G G GP GPPG G PG Sbjct: 861 ERGSPGIPGAPGPIGPPGSPGLPG 884 Score = 266 bits (679), Expect = 1e-70 Identities = 178/436 (40%), Positives = 208/436 (47%), Gaps = 108/436 (24%) Query: 257 GPPGLRGDPG---FEGERGKPGLPGEKGEAGDPGRPGDLGPVG--YQGMKGEKGSRGEKG 311 GPPG++G PG G G PG PG G G PG PG G +G +QG KGEKG +G +G Sbjct: 177 GPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQG 236 Query: 312 SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP----KGDPGAF 367 GP G E+ KR ID V+ + G GLPG +G PG GI+GPPGP KG+ G Sbjct: 237 PPGPPGQISEQ-KRPID----VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQ 291 Query: 368 GLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA------- 420 G G++G+PG DGE G+PG G GD G PGEPG GEKG+ GD G PGP G Sbjct: 292 GEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGT 351 Query: 421 ------------------PGERGGPGERGPRGTPGTRG--------PRGDPGEAGPQGDQ 454 GERG PG +GP G PG G P G PGE G +GD+ Sbjct: 352 GITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDE 411 Query: 455 GREG-----PVGVPGDPGEAGPIGPKGYRGDEGPPGSEGAR-GAPGPAGPPGDPGLMGER 508 G G P G+ G PG G GP G G PP E G PGP G PGD GL GE+ Sbjct: 412 GPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQ 471 Query: 509 GEDGPAGN--------------------------GTEGFP---------------GFPGY 527 G G G+ G+ GFP G PG Sbjct: 472 GVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI 531 Query: 528 PGNRGAPGINGTKG-------YPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQ 580 PG GAPG G+KG +PG+KGD+GE G PG P G G G G GP+ Sbjct: 532 PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLP-GTPGQDGLPGLPGPK 590 Query: 581 GPP------GHQGPPG 590 G P G +GPPG Sbjct: 591 GEPGGITFKGERGPPG 606 Score = 265 bits (677), Expect = 2e-70 Identities = 160/379 (42%), Positives = 189/379 (49%), Gaps = 54/379 (14%) Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPG---DLGPVG------YQGMKGEKGSR 307 G PG +G PG G G PG PG KG +G PG PG + GPVG G GEKG Sbjct: 1110 GTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKP 1169 Query: 308 GEKGSRGPKGYKGEKGKRG--------IDGVDGVKGEMGYPGLPGCKGSPG--------- 350 G+ G GP G KGE G+ G + G+ G KG+ G PG+PG G PG Sbjct: 1170 GQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHG 1229 Query: 351 FDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAG 410 F G+QGPPGP G PG L+G KG PG G GRPG +G G G G PG PG G G Sbjct: 1230 FPGVQGPPGPPGSPGP-ALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKG 1288 Query: 411 DEGNPGPDGAPG------ERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPG 464 ++GNPG G PG ++G PG +G G PG G +GDPG G G G +GP GVPG Sbjct: 1289 EKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPG 1348 Query: 465 ------DPGEAGPIGPKGY----------RGDEGPPG---SEGARGAPGPAGPPGDPGLM 505 +PG GP GP G +GD GPPG G +G PGP GP G PG Sbjct: 1349 SAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPT 1408 Query: 506 GERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPR 565 G G+ P NG GF G G G+ G PG GT+G G G +G G PG Sbjct: 1409 GPPGD--PGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAH 1466 Query: 566 GVKGAKGYRGPEGPQGPPG 584 G + + + PQ P G Sbjct: 1467 GFLITRHSQTTDAPQCPQG 1485 Score = 265 bits (676), Expect = 2e-70 Identities = 165/364 (45%), Positives = 186/364 (51%), Gaps = 39/364 (10%) Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG--S 312 A G PGL G P G+ G PGLPG KGE G G+ GP G G+ G G+ G G Sbjct: 568 APGLPGLPGTP---GQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG 624 Query: 313 RGPKGYKGEKGKRGI------DGVDGVKGEMG----YPGLPGCKGSPGFD---GIQGPPG 359 GP G GEKG +G+ G+ G KG+ G PG PG G+PG D G+ G PG Sbjct: 625 FGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPG 684 Query: 360 PKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDG 419 G PG G+ G KGEPG G G PG GP G G PG PG PG G G EG PGP G Sbjct: 685 LPGQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPG 743 Query: 420 APGERGG-----PGERGPRGTPGTR---GPRGDPGEAGPQGDQGREGPVGVPGDPGEAGP 471 PG +G PG GP G PG + GP+GD G GP G GR G G+PG G+ GP Sbjct: 744 FPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGP 803 Query: 472 IGPKGYRGDEGPP-----GSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPG 526 G G G G P G G G PGP G PG G+ GE+G+ GP G G PG G Sbjct: 804 NGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERG 863 Query: 527 YPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQ 586 PG GAPG G G PGL G G +G PG +G G G GP GP G PG Sbjct: 864 SPGIPGAPGPIGPPGSPGLPGKAGASGFPG-------TKGEMGMMGPPGPPGPLGIPGRS 916 Query: 587 GPPG 590 G PG Sbjct: 917 GVPG 920 Score = 261 bits (666), Expect = 3e-69 Identities = 176/457 (38%), Positives = 203/457 (44%), Gaps = 124/457 (27%) Query: 257 GPPGLRGDPG-------------FEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGE 303 GPPG+RG PG G+RGKPG GE G+ G PG PGD G G G GE Sbjct: 270 GPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGE 329 Query: 304 KGSRGEKGSRGPKGYK----------GEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDG 353 KG +G+ G GP G GEKG G+ G+ G KGE G+PG+ G G PG G Sbjct: 330 KGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG 389 Query: 354 --IQGPPGPKGDPGAFGLKGEKGEPGA--------DGEAGRPGSSGPSGDEG-------- 395 + GPPGP G PG G KG++G PG DG+ G PG GP G G Sbjct: 390 AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449 Query: 396 --QPGEPGPPG---------EKGEAGDEGN-------------------PGPDGAPGERG 425 +PG PGPPG E+G GD+G+ PG G PG G Sbjct: 450 ICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLG 509 Query: 426 GPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGD----------PGEAGPIGPK 475 PG++G +G G GP+G PG G G G G G PGD GE G G Sbjct: 510 FPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAP 569 Query: 476 GYRGDEGPPGSEGARGAPGPAG------------PPGDPGLMGERGEDGPAG-------- 515 G G G PG +G G PGP G PPG+PGL G G GP G Sbjct: 570 GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG 629 Query: 516 -------NGTEGFPGFPGYPGNRGAPGIN-------GTKGYPGLKGDEGEAGDPGDDNND 561 G G PG PG PG +G PG G G PG GD G GDPG Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689 Query: 562 IAPRGVKGAK--------GYRGPEGPQGPPGHQGPPG 590 P G+ G+K G GP GP+G PG GPPG Sbjct: 690 GLP-GIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPG 725 Score = 220 bits (561), Expect = 5e-57 Identities = 138/348 (39%), Positives = 156/348 (44%), Gaps = 86/348 (24%) Query: 329 GVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD------------------------- 363 G+ G KGE G+PGL G G PGF G +GPPGP+G Sbjct: 42 GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP 101 Query: 364 --------------------PGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGP- 402 PG G KGE+G PG+ G G G GP G G GEPG Sbjct: 102 GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSI 161 Query: 403 -----PGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGR- 456 PG KG G G PG G PG G PG GP G PG GP G PG GP+G+ G Sbjct: 162 IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLN 221 Query: 457 -EGPVGVPGDPGEAGPIGPKG-------------YRGDEGPPGSEGARGAPGPAGPPGDP 502 +GP G G+ G GP GP G +GD+G PG G G PG GPPG P Sbjct: 222 FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPP 281 Query: 503 -GLMGERGEDG-------PAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGD 554 G GE+GE G P +G G PG PG PG+ G PG G G G KGD G G Sbjct: 282 GGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGP 341 Query: 555 PG------------DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590 PG + +I G+ G KG RG G QGPPG GPPG Sbjct: 342 PGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG 389 Score = 161 bits (408), Expect = 3e-39 Identities = 103/251 (41%), Positives = 115/251 (45%), Gaps = 36/251 (14%) Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436 G EA P G G GE+G G EG+PG G PG G PG RG +G Sbjct: 21 GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80 Query: 437 GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY------RGDEGPPGSEGAR 490 G GP G G GP G G G G+PG PG G GP+G +G+ G PGS G Sbjct: 81 GIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP 140 Query: 491 GAPGPAGPPGDPGLMGERGE------DGPAGN-GTEGFPGFPGYPGNRGAPGINGTKGYP 543 G GP GPPG PG+ GE G GP GN G G PG G PG G PG G G P Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPP 200 Query: 544 GLKGDEGEAGDPGDDN----NDIAPRGVKGAKGYRGPEGP-------------------Q 580 GL G G G PG N P+G KG +G +GP GP Q Sbjct: 201 GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQ 260 Query: 581 GPPGHQGPPGP 591 G PG +GPPGP Sbjct: 261 GLPGDRGPPGP 271 Score = 52.4 bits (124), Expect = 2e-06 Identities = 27/62 (43%), Positives = 29/62 (46%) Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312 Q +G PG G PG G G PG G G GDPG PG G G G G G +G G Sbjct: 1399 QGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGP 1458 Query: 313 RG 314 G Sbjct: 1459 PG 1460 Score = 52.0 bits (123), Expect = 3e-06 Identities = 30/75 (40%), Positives = 36/75 (48%), Gaps = 3/75 (4%) Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315 +G PG +G G G G PG PG G PG G G G G+ G+ G+RG G GP Sbjct: 1393 KGLPGPQGPQGLPGPTGPPGDPGRNGL---PGFDGAGGRKGDPGLPGQPGTRGLDGPPGP 1449 Query: 316 KGYKGEKGKRGIDGV 330 G +G G G V Sbjct: 1450 DGLQGPPGPPGTSSV 1464 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.139 0.423 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 52,680,757 Number of Sequences: 37866 Number of extensions: 3550455 Number of successful extensions: 121072 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 391 Number of HSP's successfully gapped in prelim test: 1064 Number of HSP's that attempted gapping in prelim test: 12580 Number of HSP's gapped (non-prelim): 13352 length of query: 1028 length of database: 18,247,518 effective HSP length: 112 effective length of query: 916 effective length of database: 14,006,526 effective search space: 12829977816 effective search space used: 12829977816 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.