Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 87196339

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]
         (1028 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]      2122   0.0  
gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Hom...   600   e-171
gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [H...   546   e-155
gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Ho...   546   e-155
gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s...   335   1e-91
gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s...   335   1e-91
gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo ...   335   1e-91
gi|154759255 collagen, type XXVIII precursor [Homo sapiens]           333   4e-91
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     312   9e-85
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      311   2e-84
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   309   8e-84
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   309   8e-84
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     308   2e-83
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]      305   1e-82
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...   305   1e-82
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...   305   1e-82
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...   305   1e-82
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   303   7e-82
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   303   7e-82
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   303   7e-82
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]              301   3e-81
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]     300   4e-81
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]               300   4e-81
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]        300   6e-81
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]   298   1e-80
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   297   3e-80
gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]              297   3e-80
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]          295   2e-79
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   293   4e-79
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   292   1e-78

>gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]
          Length = 1028

 Score = 2122 bits (5499), Expect = 0.0
 Identities = 1028/1028 (100%), Positives = 1028/1028 (100%)

Query: 1    MRAARALLPLLLQACWTAAQDEPETPRAVAFQDCPVDLFFVLDTSESVALRLKPYGALVD 60
            MRAARALLPLLLQACWTAAQDEPETPRAVAFQDCPVDLFFVLDTSESVALRLKPYGALVD
Sbjct: 1    MRAARALLPLLLQACWTAAQDEPETPRAVAFQDCPVDLFFVLDTSESVALRLKPYGALVD 60

Query: 61   KVKSFTKRFIDNLRDRYYRCDRNLVWNAGALHYSDEVEIIQGLTRMPGGRDALKSSVDAV 120
            KVKSFTKRFIDNLRDRYYRCDRNLVWNAGALHYSDEVEIIQGLTRMPGGRDALKSSVDAV
Sbjct: 61   KVKSFTKRFIDNLRDRYYRCDRNLVWNAGALHYSDEVEIIQGLTRMPGGRDALKSSVDAV 120

Query: 121  KYFGKGTYTDCAIKKGLEQLLVGGSHLKENKYLIVVTDGHPLEGYKEPCGGLEDAVNEAK 180
            KYFGKGTYTDCAIKKGLEQLLVGGSHLKENKYLIVVTDGHPLEGYKEPCGGLEDAVNEAK
Sbjct: 121  KYFGKGTYTDCAIKKGLEQLLVGGSHLKENKYLIVVTDGHPLEGYKEPCGGLEDAVNEAK 180

Query: 181  HLGVKVFSVAITPDHLEPRLSIIATDHTYRRNFTAADWGQSRDAEEAISQTIDTIVDMIK 240
            HLGVKVFSVAITPDHLEPRLSIIATDHTYRRNFTAADWGQSRDAEEAISQTIDTIVDMIK
Sbjct: 181  HLGVKVFSVAITPDHLEPRLSIIATDHTYRRNFTAADWGQSRDAEEAISQTIDTIVDMIK 240

Query: 241  NNVEQVCCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGM 300
            NNVEQVCCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGM
Sbjct: 241  NNVEQVCCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGM 300

Query: 301  KGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP 360
            KGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP
Sbjct: 301  KGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP 360

Query: 361  KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA 420
            KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA
Sbjct: 361  KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA 420

Query: 421  PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480
            PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD
Sbjct: 421  PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480

Query: 481  EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTK 540
            EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTK
Sbjct: 481  EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTK 540

Query: 541  GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPDECEILDII 600
            GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPDECEILDII
Sbjct: 541  GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPDECEILDII 600

Query: 601  MKMCSCCECKCGPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYA 660
            MKMCSCCECKCGPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYA
Sbjct: 601  MKMCSCCECKCGPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYA 660

Query: 661  GVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPN 720
            GVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPN
Sbjct: 661  GVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPN 720

Query: 721  NRIALVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPS 780
            NRIALVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPS
Sbjct: 721  NRIALVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPS 780

Query: 781  QGRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASV 840
            QGRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASV
Sbjct: 781  QGRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASV 840

Query: 841  GSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTAL 900
            GSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTAL
Sbjct: 841  GSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTAL 900

Query: 901  ASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQ 960
            ASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQ
Sbjct: 901  ASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQ 960

Query: 961  EAQRAGIEIFVVVVGRQVNEPHIRVLVTGKTAEYDVAYGESHLFRVPSYQALLRGVFHQT 1020
            EAQRAGIEIFVVVVGRQVNEPHIRVLVTGKTAEYDVAYGESHLFRVPSYQALLRGVFHQT
Sbjct: 961  EAQRAGIEIFVVVVGRQVNEPHIRVLVTGKTAEYDVAYGESHLFRVPSYQALLRGVFHQT 1020

Query: 1021 VSRKVALG 1028
            VSRKVALG
Sbjct: 1021 VSRKVALG 1028


>gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Homo
           sapiens]
          Length = 1019

 Score =  600 bits (1546), Expect = e-171
 Identities = 363/985 (36%), Positives = 524/985 (53%), Gaps = 57/985 (5%)

Query: 33  DCPVDLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLRDRYYRCDRNLVWNAGALH 92
           DCP+ ++FVLDTSESV ++  P   L+  +K F  +FI  L++ +Y     L W  G LH
Sbjct: 42  DCPIHVYFVLDTSESVTMQ-SPTDILLFHMKQFVPQFISQLQNEFYLDQVALSWRYGGLH 100

Query: 93  YSDEVEIIQGLTRMPGG-RDALKSSVDAVKYFGKGTYTDCAIKKGLEQLLVGGSHLKENK 151
           +SD+VE+       PG  R +   ++  +  F +GT+TDCA+    EQ+    S    + 
Sbjct: 101 FSDQVEVFSP----PGSDRASFIKNLQGISSFRRGTFTDCALANMTEQIRQDRSKGTVH- 155

Query: 152 YLIVVTDGHPLEGYKEPCGGLEDAVNEAKHLGVKVFSVAITPDHLEPRLSIIA-TDHTYR 210
           + +V+TDGH       PCGG++     A+  G+++F+VA   +  E  L  IA T H   
Sbjct: 156 FAVVITDGHVTGS---PCGGIKLQAERAREEGIRLFAVAPNQNLKEQGLRDIASTPHELY 212

Query: 211 RNFTAADWGQSRDAEEAISQTIDTIVDMIKNNVEQVCCSFECQPARGPPGLRGDPGFEGE 270
           RN  A       D+ E    TI+ I+ ++K+     C    C    GP G +G  G +G 
Sbjct: 213 RNDYAT---MLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIPGPSGPKGYRGQKGA 269

Query: 271 RGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGV 330
           +G  G PGE G+ G  G PG  GP+G+ G KG  G +GEKG  G  G KG  G  G +G 
Sbjct: 270 KGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGT 329

Query: 331 DGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGP 390
           DG KG++G  G PGCKG PG  G  G PG  G PG  G +G KG+PG  G  G PG  G 
Sbjct: 330 DGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGA 389

Query: 391 SGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGP 450
            G +G  G  G PG  G  G +G PGP G  GE G  G+ G +G+PG+ GP+G+ G+ GP
Sbjct: 390 KGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGP 449

Query: 451 QGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGE 510
           +G +G  G VG  G  G+ G  GP+G +G  G PG +G+RG PG AGP GD G  G +G+
Sbjct: 450 EGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGD 509

Query: 511 DGPAG---NGTEGFPGFPGYPGNRGAPGIN---GTKGYPGLKGDEGEAGDPGDDNNDIAP 564
            G  G    G  G PG  G PG RG  G     G KG PG KG++GE  DPG       P
Sbjct: 510 PGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPG-------P 562

Query: 565 RGVKGAKGYRGPEGPQGPPGHQGPPGPDECEILDIIMKMCSCCEC--KCGPIDLLFVLDS 622
            G  G +G RG  GP+G PG  G PG  EC+++  + + C CC+C  +CG +D++FV+DS
Sbjct: 563 PGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKRCGALDVVFVIDS 622

Query: 623 SESIGLQNFEIAKDFVVKVIDRL---SRDELVKFEPGQSYAGVVQYSHSQMQEHVSLRSP 679
           SESIG  NF + K+FV+ V++RL   ++D   K E G +  GVVQYSH    E + L   
Sbjct: 623 SESIGYTNFTLEKNFVINVVNRLGAIAKDP--KSETG-TRVGVVQYSHEGTFEAIQLDDE 679

Query: 680 SIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNR---IALVITDGRSDTQR 736
            I ++   KEA+K+L+W+AGGT+T  AL++  D+L+  S   +    A+VITDGR D + 
Sbjct: 680 RIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVFAVVITDGRHDPRD 739

Query: 737 DTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLSLVKENYAEL 796
           D   L  LC   + V ++GI D+F     S+ L  I+C    P Q R  ++L    +++L
Sbjct: 740 DDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACD--KPQQVR-NMTL----FSDL 792

Query: 797 LEDAFLKNVTAQICIDKK--CPDYTCPITFS------SPADITILLDGSASVGSHNFDTT 848
           + + F+ ++   +C D +  CPD  C    S       P DI  LLDGS  +G  NF   
Sbjct: 793 VAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRPVDIVFLLDGSERLGEQNFHKA 852

Query: 849 KRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASAVDAMD 908
           +RF +++A R   A R D   + RVA++Q+ G G+Q   + +     N TA+  A++   
Sbjct: 853 RRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQ---QVAFPLSHNLTAIHEALETTQ 909

Query: 909 FINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGAT-PAAIEKAVQEAQRAGI 967
           ++N  + V   + +       +  G A++   L     + G T   ++ ++    ++  +
Sbjct: 910 YLNSFSHVGAGVVHAINAIVRSPRGGARRHAELSFVFLTDGVTGNDSLHESAHSMRKQNV 969

Query: 968 EIFVVVVGRQVNEPHIRVLVTGKTA 992
              V+ +G  V+   +  L  G  A
Sbjct: 970 VPTVLALGSDVDMDVLTTLSLGDRA 994



 Score = 35.4 bits (80), Expect = 0.28
 Identities = 37/134 (27%), Positives = 62/134 (46%), Gaps = 14/134 (10%)

Query: 605 SCCECKCGPIDLLFVLDSSESIGLQN------FEIAKDFVVKVIDRLSRDELVKFEPGQS 658
           +C E    PI + FVLD+SES+ +Q+      F + K FV + I +L ++E    +   S
Sbjct: 36  NCPEKTDCPIHVYFVLDTSESVTMQSPTDILLFHM-KQFVPQFISQL-QNEFYLDQVALS 93

Query: 659 YAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPS 718
           +    +Y      + V + SP   +     + ++ +     GTFT  AL    +Q+    
Sbjct: 94  W----RYGGLHFSDQVEVFSPPGSDRASFIKNLQGISSFRRGTFTDCALANMTEQIRQDR 149

Query: 719 PNNRI--ALVITDG 730
               +  A+VITDG
Sbjct: 150 SKGTVHFAVVITDG 163


>gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [Homo
           sapiens]
          Length = 828

 Score =  546 bits (1408), Expect = e-155
 Identities = 320/806 (39%), Positives = 446/806 (55%), Gaps = 47/806 (5%)

Query: 33  DCPVDLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLRDRYYRCDRNLVWNAGALH 92
           DCP+ ++FVLDTSESV ++  P   L+  +K F  +FI  L++ +Y     L W  G LH
Sbjct: 42  DCPIHVYFVLDTSESVTMQ-SPTDILLFHMKQFVPQFISQLQNEFYLDQVALSWRYGGLH 100

Query: 93  YSDEVEIIQGLTRMPGG-RDALKSSVDAVKYFGKGTYTDCAIKKGLEQLLVGGSHLKENK 151
           +SD+VE+       PG  R +   ++  +  F +GT+TDCA+    EQ+    S    + 
Sbjct: 101 FSDQVEVFSP----PGSDRASFIKNLQGISSFRRGTFTDCALANMTEQIRQDRSKGTVH- 155

Query: 152 YLIVVTDGHPLEGYKEPCGGLEDAVNEAKHLGVKVFSVAITPDHLEPRLSIIA-TDHTYR 210
           + +V+TDGH       PCGG++     A+  G+++F+VA   +  E  L  IA T H   
Sbjct: 156 FAVVITDGHVTGS---PCGGIKLQAERAREEGIRLFAVAPNQNLKEQGLRDIASTPHELY 212

Query: 211 RNFTAADWGQSRDAEEAISQTIDTIVDMIKNNVEQVCCSFECQPARGPPGLRGDPGFEGE 270
           RN  A       D+ E    TI+ I+ ++K+     C    C    GP G +G  G +G 
Sbjct: 213 RNDYAT---MLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIPGPSGPKGYRGQKGA 269

Query: 271 RGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGV 330
           +G  G PGE G+ G  G PG  GP+G+ G KG  G +GEKG  G  G KG  G  G +G 
Sbjct: 270 KGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGT 329

Query: 331 DGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGP 390
           DG KG++G  G PGCKG PG  G  G PG  G PG  G +G KG+PG  G  G PG  G 
Sbjct: 330 DGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGA 389

Query: 391 SGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGP 450
            G +G  G  G PG  G  G +G PGP G  GE G  G+ G +G+PG+ GP+G+ G+ GP
Sbjct: 390 KGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGP 449

Query: 451 QGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGE 510
           +G +G  G VG  G  G+ G  GP+G +G  G PG +G+RG PG AGP GD G  G +G+
Sbjct: 450 EGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGD 509

Query: 511 DGPAG---NGTEGFPGFPGYPGNRGAPGIN---GTKGYPGLKGDEGEAGDPGDDNNDIAP 564
            G  G    G  G PG  G PG RG  G     G KG PG KG++GE  DPG       P
Sbjct: 510 PGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPG-------P 562

Query: 565 RGVKGAKGYRGPEGPQGPPGHQGPPGPDECEILDIIMKMCSCCEC--KCGPIDLLFVLDS 622
            G  G +G RG  GP+G PG  G PG  EC+++  + + C CC+C  +CG +D++FV+DS
Sbjct: 563 PGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKRCGALDVVFVIDS 622

Query: 623 SESIGLQNFEIAKDFVVKVIDRL---SRDELVKFEPGQSYAGVVQYSHSQMQEHVSLRSP 679
           SESIG  NF + K+FV+ V++RL   ++D   K E G +  GVVQYSH    E + L   
Sbjct: 623 SESIGYTNFTLEKNFVINVVNRLGAIAKDP--KSETG-TRVGVVQYSHEGTFEAIQLDDE 679

Query: 680 SIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNR---IALVITDGRSDTQR 736
            I ++   KEA+K+L+W+AGGT+T  AL++  D+L+  S   +    A+VITDGR D + 
Sbjct: 680 RIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVFAVVITDGRHDPRD 739

Query: 737 DTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLSLVKENYAEL 796
           D   L  LC   + V ++GI D+F     S+ L  I+C    P Q R  ++L    +++L
Sbjct: 740 DDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACD--KPQQVR-NMTL----FSDL 792

Query: 797 LEDAFLKNVTAQICIDKK--CPDYTC 820
           + + F+ ++   +C D +  CPD  C
Sbjct: 793 VAEKFIDDMEDVLCPDPQIVCPDLPC 818



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 4/120 (3%)

Query: 829 DITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHD--VRVAVVQYSGTGQQRP 886
           D+  ++D S S+G  NF   K F   +  R L A   DP  +   RV VVQYS  G    
Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNR-LGAIAKDPKSETGTRVGVVQYSHEGTFEA 673

Query: 887 ERASLQFLQNYTALASAVDAMDFINDATDVNDALGYV-TRFYREASSGAAKKRLLLFSDG 945
            +   + + + ++   AV  +++I   T    AL +   R  +E+     +   ++ +DG
Sbjct: 674 IQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVFAVVITDG 733



 Score = 35.4 bits (80), Expect = 0.28
 Identities = 37/134 (27%), Positives = 62/134 (46%), Gaps = 14/134 (10%)

Query: 605 SCCECKCGPIDLLFVLDSSESIGLQN------FEIAKDFVVKVIDRLSRDELVKFEPGQS 658
           +C E    PI + FVLD+SES+ +Q+      F + K FV + I +L ++E    +   S
Sbjct: 36  NCPEKTDCPIHVYFVLDTSESVTMQSPTDILLFHM-KQFVPQFISQL-QNEFYLDQVALS 93

Query: 659 YAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPS 718
           +    +Y      + V + SP   +     + ++ +     GTFT  AL    +Q+    
Sbjct: 94  W----RYGGLHFSDQVEVFSPPGSDRASFIKNLQGISSFRRGTFTDCALANMTEQIRQDR 149

Query: 719 PNNRI--ALVITDG 730
               +  A+VITDG
Sbjct: 150 SKGTVHFAVVITDG 163


>gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Homo
           sapiens]
          Length = 918

 Score =  546 bits (1408), Expect = e-155
 Identities = 320/806 (39%), Positives = 446/806 (55%), Gaps = 47/806 (5%)

Query: 33  DCPVDLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLRDRYYRCDRNLVWNAGALH 92
           DCP+ ++FVLDTSESV ++  P   L+  +K F  +FI  L++ +Y     L W  G LH
Sbjct: 42  DCPIHVYFVLDTSESVTMQ-SPTDILLFHMKQFVPQFISQLQNEFYLDQVALSWRYGGLH 100

Query: 93  YSDEVEIIQGLTRMPGG-RDALKSSVDAVKYFGKGTYTDCAIKKGLEQLLVGGSHLKENK 151
           +SD+VE+       PG  R +   ++  +  F +GT+TDCA+    EQ+    S    + 
Sbjct: 101 FSDQVEVFSP----PGSDRASFIKNLQGISSFRRGTFTDCALANMTEQIRQDRSKGTVH- 155

Query: 152 YLIVVTDGHPLEGYKEPCGGLEDAVNEAKHLGVKVFSVAITPDHLEPRLSIIA-TDHTYR 210
           + +V+TDGH       PCGG++     A+  G+++F+VA   +  E  L  IA T H   
Sbjct: 156 FAVVITDGHVTGS---PCGGIKLQAERAREEGIRLFAVAPNQNLKEQGLRDIASTPHELY 212

Query: 211 RNFTAADWGQSRDAEEAISQTIDTIVDMIKNNVEQVCCSFECQPARGPPGLRGDPGFEGE 270
           RN  A       D+ E    TI+ I+ ++K+     C    C    GP G +G  G +G 
Sbjct: 213 RNDYAT---MLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIPGPSGPKGYRGQKGA 269

Query: 271 RGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGV 330
           +G  G PGE G+ G  G PG  GP+G+ G KG  G +GEKG  G  G KG  G  G +G 
Sbjct: 270 KGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGT 329

Query: 331 DGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGP 390
           DG KG++G  G PGCKG PG  G  G PG  G PG  G +G KG+PG  G  G PG  G 
Sbjct: 330 DGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGA 389

Query: 391 SGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGP 450
            G +G  G  G PG  G  G +G PGP G  GE G  G+ G +G+PG+ GP+G+ G+ GP
Sbjct: 390 KGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGP 449

Query: 451 QGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGE 510
           +G +G  G VG  G  G+ G  GP+G +G  G PG +G+RG PG AGP GD G  G +G+
Sbjct: 450 EGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGD 509

Query: 511 DGPAG---NGTEGFPGFPGYPGNRGAPGIN---GTKGYPGLKGDEGEAGDPGDDNNDIAP 564
            G  G    G  G PG  G PG RG  G     G KG PG KG++GE  DPG       P
Sbjct: 510 PGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPG-------P 562

Query: 565 RGVKGAKGYRGPEGPQGPPGHQGPPGPDECEILDIIMKMCSCCEC--KCGPIDLLFVLDS 622
            G  G +G RG  GP+G PG  G PG  EC+++  + + C CC+C  +CG +D++FV+DS
Sbjct: 563 PGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKRCGALDVVFVIDS 622

Query: 623 SESIGLQNFEIAKDFVVKVIDRL---SRDELVKFEPGQSYAGVVQYSHSQMQEHVSLRSP 679
           SESIG  NF + K+FV+ V++RL   ++D   K E G +  GVVQYSH    E + L   
Sbjct: 623 SESIGYTNFTLEKNFVINVVNRLGAIAKDP--KSETG-TRVGVVQYSHEGTFEAIQLDDE 679

Query: 680 SIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNR---IALVITDGRSDTQR 736
            I ++   KEA+K+L+W+AGGT+T  AL++  D+L+  S   +    A+VITDGR D + 
Sbjct: 680 RIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVFAVVITDGRHDPRD 739

Query: 737 DTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLSLVKENYAEL 796
           D   L  LC   + V ++GI D+F     S+ L  I+C    P Q R  ++L    +++L
Sbjct: 740 DDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACD--KPQQVR-NMTL----FSDL 792

Query: 797 LEDAFLKNVTAQICIDKK--CPDYTC 820
           + + F+ ++   +C D +  CPD  C
Sbjct: 793 VAEKFIDDMEDVLCPDPQIVCPDLPC 818



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 4/120 (3%)

Query: 829 DITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHD--VRVAVVQYSGTGQQRP 886
           D+  ++D S S+G  NF   K F   +  R L A   DP  +   RV VVQYS  G    
Sbjct: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNR-LGAIAKDPKSETGTRVGVVQYSHEGTFEA 673

Query: 887 ERASLQFLQNYTALASAVDAMDFINDATDVNDALGYV-TRFYREASSGAAKKRLLLFSDG 945
            +   + + + ++   AV  +++I   T    AL +   R  +E+     +   ++ +DG
Sbjct: 674 IQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVFAVVITDG 733



 Score = 35.4 bits (80), Expect = 0.28
 Identities = 37/134 (27%), Positives = 62/134 (46%), Gaps = 14/134 (10%)

Query: 605 SCCECKCGPIDLLFVLDSSESIGLQN------FEIAKDFVVKVIDRLSRDELVKFEPGQS 658
           +C E    PI + FVLD+SES+ +Q+      F + K FV + I +L ++E    +   S
Sbjct: 36  NCPEKTDCPIHVYFVLDTSESVTMQSPTDILLFHM-KQFVPQFISQL-QNEFYLDQVALS 93

Query: 659 YAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPS 718
           +    +Y      + V + SP   +     + ++ +     GTFT  AL    +Q+    
Sbjct: 94  W----RYGGLHFSDQVEVFSPPGSDRASFIKNLQGISSFRRGTFTDCALANMTEQIRQDR 149

Query: 719 PNNRI--ALVITDG 730
               +  A+VITDG
Sbjct: 150 SKGTVHFAVVITDG 163


>gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo
            sapiens]
          Length = 2971

 Score =  335 bits (859), Expect = 1e-91
 Identities = 252/790 (31%), Positives = 359/790 (45%), Gaps = 72/790 (9%)

Query: 235  IVDMIKNNVEQVCCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP 294
            + + + N  E+ CC   C+   G  G RG  G  G +G PG  G +G  GD G PG+ GP
Sbjct: 1811 LAEQLDNIAEKACCGVPCK-CSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGP 1869

Query: 295  VGY---QGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGF 351
             G    QG +G  G RG KGSRG  G KGE G+ G+DG+DG  G+ G PG  G KG+PG 
Sbjct: 1870 PGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGR 1929

Query: 352  DGIQGPPGPKGDPGAFGLKGEKGEPGAD----GEAGRPGSSGPSGDEGQPGEPGPPGEKG 407
             G +GP G KG+ G  G++G+ G PG D    G  G  G  GP G  G+ G PG PGE G
Sbjct: 1930 RGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETG 1989

Query: 408  EAGDEGNPGPDGAPGERGGPG------ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVG 461
            + G  G  GP GA G +GGPG      E+G RG  G  GP G PG  G QG  G  G  G
Sbjct: 1990 KNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGG 2049

Query: 462  VPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGF 521
              G PGE G  GP G +G+ G PG +G  G  GP G  GD G  G   E      G  GF
Sbjct: 2050 AAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGF 2109

Query: 522  PGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQG 581
            PG+PG  GN G PG+NGT G  G++G  G +G P          G+ G KG  G  GP G
Sbjct: 2110 PGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPP----------GIVGQKGDPGYPGPAG 2159

Query: 582  PPGHQGPPGPDECEILDIIMKMCSCC----ECKCGPIDLLFVLDSSESIGLQNFEIAKDF 637
            P G++G    D+C ++  I   C CC    EC   P +L F LD+SE +    F   +D 
Sbjct: 2160 PKGNRG-DSIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVNQDTFGRMRDV 2218

Query: 638  VVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQ-- 695
            V+ +++ L+  E     P  +   VV Y++    E   +R    +    L + IK+LQ  
Sbjct: 2219 VLSIVNDLTIAE--SNCPRGARVAVVTYNNEVTTE---IRFADSKRKSVLLDKIKNLQVA 2273

Query: 696  WMAGGTFTGEALQYTRDQLLPPSPNNRIALVITDGRSDTQRDTTPLNVLCSPGIQVVSVG 755
              +       A+ +          N  +   +    S+T    +P   L    +++   G
Sbjct: 2274 LTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTRASP--QLREAVLKLSDAG 2331

Query: 756  IKDVFDFIPGSDQLNVISCQGLAPSQGRPGLSLVKENYAELLEDAFLKNV-TAQICIDKK 814
            I  +F       QL       L  +    G +LV     +L +  FL+NV T  +C+D  
Sbjct: 2332 ITPLFLTRQEDRQL----INALQINNTAVGHALVLPAGRDLTD--FLENVLTCHVCLDIC 2385

Query: 815  CPDYTCPITFSSPA-------------DITILLDGSASVGSHNFDTTKRFAKRLAERF-L 860
              D +C      P+             D+  +LD + +     F+  K++   L  +  +
Sbjct: 2386 NIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDM 2445

Query: 861  TAGRTDPAHDVRVAVVQYSGTGQQRPERASLQ------FLQNYTALASAVD----AMDFI 910
            +       H  RVAVVQ++ +  +  + AS+        L +Y +    VD     M  +
Sbjct: 2446 SPDPKASQHFARVAVVQHAPS--ESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQL 2503

Query: 911  NDATDVNDALGY-VTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQEAQRAGIEI 969
                 +  A+ Y +   +  A +    K ++L   G          ++ + +A+  G   
Sbjct: 2504 QGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFF 2563

Query: 970  FVVVVGRQVN 979
             V+ +GR+VN
Sbjct: 2564 VVLGIGRKVN 2573



 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 97/372 (26%), Positives = 141/372 (37%), Gaps = 54/372 (14%)

Query: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQS--YAGVVQYSHSQMQE 672
           D++F++D S ++GL NF   +DF+ KVI RL        E GQ      V QY+ +   E
Sbjct: 239 DIVFLVDGSSALGLANFNAIRDFIAKVIQRL--------EIGQDLIQVAVAQYADTVRPE 290

Query: 673 HVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNRIA------LV 726
                 P+ R V      +K L   A   +TG AL + R+ L   S   R A      LV
Sbjct: 291 FYFNTHPTKREVITAVRKMKPLDGSA--LYTGSALDFVRNNLFTSSAGYRAAEGIPKLLV 348

Query: 727 ITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGL 786
           +  G       + P   L    I   ++G K       G+DQ        L        L
Sbjct: 349 LITGGKSLDEISQPAQELKRSSIMAFAIGNK-------GADQAE------LEEIAFDSSL 395

Query: 787 SLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHNFD 846
             +   +        L  + A +      P+       S+  DI  LLDGSA+VG  NF 
Sbjct: 396 VFIPAEFRAAPLQGMLPGLLAPLRTLSGTPE-----VHSNKRDIIFLLDGSANVGKTNFP 450

Query: 847 TTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASAVDA 906
             + F   L    L  G      ++RV +VQ+S T        SL   Q  + +   +  
Sbjct: 451 YVRDFVMNLVNS-LDIGN----DNIRVGLVQFSDT---PVTEFSLNTYQTKSDILGHLRQ 502

Query: 907 MDFI-NDATDVNDALGYV-TRFYREASSGAAKKR----LLLFSDGNSQGATPAAIEKAVQ 960
           +        +   AL YV    + EA     ++     LLL + G S+     +  +A  
Sbjct: 503 LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSED----SYLQAAN 558

Query: 961 EAQRAGIEIFVV 972
              RAGI  F V
Sbjct: 559 ALTRAGILTFCV 570



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 70/305 (22%), Positives = 124/305 (40%), Gaps = 44/305 (14%)

Query: 615  DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674
            D++F++DSSE +    F   +DFV +++ RL+        P +   GVVQ+S+    E  
Sbjct: 1230 DIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLN------IGPSKVRVGVVQFSNDVFPE-- 1281

Query: 675  SLRSPSIRNVQELKEAIKSLQWMAGGTF-TGEALQYTRDQLLPPSPNNRIA------LVI 727
                 + R+   + +AI+ L+   G    TG+AL++    L   S  +RI       LV+
Sbjct: 1282 -FYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVL 1340

Query: 728  TDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLS 787
              G       +    V+ S GI  + VG +++        +L  I+          P L 
Sbjct: 1341 VLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNI-----DRTELQTIT--------NDPRLV 1387

Query: 788  LVKENYAEL--LEDAFLKNVTAQICIDKKCPDYTCPIT--FSSPADITILLDGSASVGSH 843
                 + EL  +E+  + +              T P +      ADI  LLDGS +    
Sbjct: 1388 FTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRD 1447

Query: 844  NFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASA 903
            +F    RF   + +     G       ++V +VQY+       +     FL++++     
Sbjct: 1448 SFQEVLRFVSEIVDTVYEDG-----DSIQVGLVQYNS------DPTDEFFLKDFSTKRQI 1496

Query: 904  VDAMD 908
            +DA++
Sbjct: 1497 IDAIN 1501



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 89/373 (23%), Positives = 151/373 (40%), Gaps = 47/373 (12%)

Query: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674
           D++F++D S + G  NF +  DF+V ++++L           Q   GVVQ+S  + +   
Sbjct: 36  DIIFLIDGSNNTGSVNFAVILDFLVNLLEKL------PIGTQQIRVGVVQFS-DEPRTMF 88

Query: 675 SLRSPSIRNVQELKEAIKSLQWMAGGTFT--GEALQYTRDQLLPPSPNNRIALVITDGRS 732
           SL + S +   ++  A+K+L + AGG     G AL +  +     +  +R+         
Sbjct: 89  SLDTYSTK--AQVLGAVKALGF-AGGELANIGLALDFVVENHFTRAGGSRV--------- 136

Query: 733 DTQRDTTPLNVLCSPG-------IQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPG 785
             +     + VL S G         VV++    VF F  G+   +    Q +A       
Sbjct: 137 --EEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVF 194

Query: 786 LSLVKENYAELLEDAFLKNV-TAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHN 844
                 ++ +L E      V  AQ  I  K P     +   +  DI  L+DGS+++G  N
Sbjct: 195 TVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLAN 254

Query: 845 FDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASAV 904
           F+  + F  ++ +R L  G+      ++VAV QY+ T   RPE            + +  
Sbjct: 255 FNAIRDFIAKVIQR-LEIGQ----DLIQVAVAQYADT--VRPEFYFNTHPTKREVITAVR 307

Query: 905 DAMDFINDATDVNDALGYVTRFYREASSG-----AAKKRLLLFSDGNSQGATPAAIEKAV 959
                   A     AL +V      +S+G        K L+L + G S       I +  
Sbjct: 308 KMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLD----EISQPA 363

Query: 960 QEAQRAGIEIFVV 972
           QE +R+ I  F +
Sbjct: 364 QELKRSSIMAFAI 376



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 89/358 (24%), Positives = 148/358 (41%), Gaps = 55/358 (15%)

Query: 612  GPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQ 671
            G  D++F++D S+S G + F+  +  + +++D L     V F+  +    V+Q+S     
Sbjct: 1024 GKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLD----VGFDTTR--VAVIQFSDDPKV 1076

Query: 672  EHVSLRSPSIRNVQELKEAIKSLQWMAGGTFT-GEALQYTRDQLLPPSPNNRIA------ 724
            E + L + S ++  E++ A++ L+   G     G AL+Y    +      +RI       
Sbjct: 1077 EFL-LNAHSSKD--EVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQF 1133

Query: 725  -LVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGR 783
             ++I+ G+SD + D         P +++   G+   F     +DQ  ++    L+P    
Sbjct: 1134 LVLISSGKSDDEVD--------DPAVELKQFGVAP-FTIARNADQEELVKIS-LSPEYV- 1182

Query: 784  PGLSLVKENYAELLEDAFLKNVTA----QICIDKKCPDYTCPITFSSPADITILLDGSAS 839
               S+        LE   L  +T     QI        Y  P   S  ADI  L+D S  
Sbjct: 1183 --FSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEG 1240

Query: 840  VGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTA 899
            V    F   + F  R+  R L  G +     VRV VVQ+S      PE     +L+ Y +
Sbjct: 1241 VRPDGFAHIRDFVSRIVRR-LNIGPS----KVRVGVVQFS--NDVFPE----FYLKTYRS 1289

Query: 900  LASAVDAMDFI----NDATDVNDALGYVTR--FYREASS---GAAKKRLLLFSDGNSQ 948
             A  +DA+  +        +   AL +V R  F + A S       + L+L   G SQ
Sbjct: 1290 QAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQ 1347



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 65/275 (23%), Positives = 112/275 (40%), Gaps = 42/275 (15%)

Query: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674
           D++F+LD S ++G  NF   +DFV+ +++ L               G+VQ+S + + E  
Sbjct: 433 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD------IGNDNIRVGLVQFSDTPVTE-F 485

Query: 675 SLRSPSIRNVQELKEAIKSLQWMAG-GTFTGEALQYTRDQLLPPSPNNRI-------ALV 726
           SL +   ++  ++   ++ LQ   G G  TG AL Y        +  +RI        L+
Sbjct: 486 SLNTYQTKS--DILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLL 543

Query: 727 ITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGL 786
           +T G+S+        N L   GI            F  G+ Q N    + +A     P L
Sbjct: 544 LTAGQSEDSY-LQAANALTRAGI----------LTFCVGASQANKAELEQIA---FNPSL 589

Query: 787 SLVKENYAEL--LEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHN 844
             + ++++ L  L    ++ +T  +    +      P    S  DI  L DGSA++    
Sbjct: 590 VYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQP---ESKRDILFLFDGSANLVG-Q 645

Query: 845 FDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYS 879
           F   + F  ++ +              R+AV QYS
Sbjct: 646 FPVVRDFLYKIIDEL-----NVKPEGTRIAVAQYS 675



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 87/396 (21%), Positives = 160/396 (40%), Gaps = 46/396 (11%)

Query: 615  DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQS-YAGVVQYSHSQMQEH 673
            D++F+LD S +    +F+    FV +++D +       +E G S   G+VQY +S   + 
Sbjct: 1433 DIVFLLDGSINFRRDSFQEVLRFVSEIVDTV-------YEDGDSIQVGLVQY-NSDPTDE 1484

Query: 674  VSLRSPSIRNVQELKEAIKSLQWMAG-GTFTGEALQYTRDQLLPPSPNNR-------IAL 725
              L+  S +  +++ +AI  + +  G    T   L++ R     P   +R       IA 
Sbjct: 1485 FFLKDFSTK--RQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAF 1542

Query: 726  VITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPG 785
            VIT G+S        L  L   G++V +VG++++     G    N  +   +   Q    
Sbjct: 1543 VITGGKSVEDAQDVSL-ALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQ---E 1598

Query: 786  LSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSAS----VG 841
            LS + E   E L DA  + +         CP  T     +   D+ +  DGS      V 
Sbjct: 1599 LSELSEQVLETLHDAMHETL---------CPGVT-DAAKACNLDVILGFDGSRDQNVFVA 1648

Query: 842  SHNFDT-TKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTAL 900
               F++       R+++    +     +  VRV+VV  + +G       +  F +    +
Sbjct: 1649 QKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVE----AFDFDEYQPEM 1704

Query: 901  ASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQ 960
                  M   +      D L      +R++S  + K  ++ F+DG       A + +A +
Sbjct: 1705 LEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVKV-VIHFTDG--ADGDLADLHRASE 1761

Query: 961  EAQRAGIEIFVVV-VGRQVNEPHIRVLVTGKTAEYD 995
              ++ G+   ++V + R VN   +  L  G+   YD
Sbjct: 1762 NLRQEGVRALILVGLERVVNLERLMHLEFGRGFMYD 1797



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 38/169 (22%), Positives = 75/169 (44%), Gaps = 20/169 (11%)

Query: 614  IDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEH 673
            ID+ F+LDS+E+  L  F   K ++  ++ +L      K     +   VVQ++ S+  ++
Sbjct: 2412 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2471

Query: 674  VSLRSPSIR-------NVQELKEAI-KSLQWMAGGTFTGEALQYTRDQLLPPSPNNR--- 722
             S+    +        + ++L + + + +  + G    G A++YT + +   +PN R   
Sbjct: 2472 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLK 2531

Query: 723  -IALVITDGRSDTQRDTTP---LNVLCSPGIQVV-----SVGIKDVFDF 762
             + L++T    + Q +      L   C     VV      V IK+V+ F
Sbjct: 2532 IVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTF 2580



 Score = 34.3 bits (77), Expect = 0.62
 Identities = 37/126 (29%), Positives = 54/126 (42%), Gaps = 14/126 (11%)

Query: 828 ADITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPE 887
           ADI  L+DGS + GS NF     F   L E+ L  G       +RV VVQ+S    +   
Sbjct: 35  ADIIFLIDGSNNTGSVNFAVILDFLVNLLEK-LPIG----TQQIRVGVVQFS---DEPRT 86

Query: 888 RASLQFLQNYTALASAVDAMDFI-NDATDVNDALGYVTRFYREASSGAAKKR-----LLL 941
             SL        +  AV A+ F   +  ++  AL +V   +   + G+  +      L+L
Sbjct: 87  MFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVL 146

Query: 942 FSDGNS 947
            S G S
Sbjct: 147 ISAGPS 152


>gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
            sapiens]
          Length = 3177

 Score =  335 bits (859), Expect = 1e-91
 Identities = 252/790 (31%), Positives = 359/790 (45%), Gaps = 72/790 (9%)

Query: 235  IVDMIKNNVEQVCCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP 294
            + + + N  E+ CC   C+   G  G RG  G  G +G PG  G +G  GD G PG+ GP
Sbjct: 2017 LAEQLDNIAEKACCGVPCK-CSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGP 2075

Query: 295  VGY---QGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGF 351
             G    QG +G  G RG KGSRG  G KGE G+ G+DG+DG  G+ G PG  G KG+PG 
Sbjct: 2076 PGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGR 2135

Query: 352  DGIQGPPGPKGDPGAFGLKGEKGEPGAD----GEAGRPGSSGPSGDEGQPGEPGPPGEKG 407
             G +GP G KG+ G  G++G+ G PG D    G  G  G  GP G  G+ G PG PGE G
Sbjct: 2136 RGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETG 2195

Query: 408  EAGDEGNPGPDGAPGERGGPG------ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVG 461
            + G  G  GP GA G +GGPG      E+G RG  G  GP G PG  G QG  G  G  G
Sbjct: 2196 KNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGG 2255

Query: 462  VPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGF 521
              G PGE G  GP G +G+ G PG +G  G  GP G  GD G  G   E      G  GF
Sbjct: 2256 AAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGF 2315

Query: 522  PGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQG 581
            PG+PG  GN G PG+NGT G  G++G  G +G P          G+ G KG  G  GP G
Sbjct: 2316 PGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPP----------GIVGQKGDPGYPGPAG 2365

Query: 582  PPGHQGPPGPDECEILDIIMKMCSCC----ECKCGPIDLLFVLDSSESIGLQNFEIAKDF 637
            P G++G    D+C ++  I   C CC    EC   P +L F LD+SE +    F   +D 
Sbjct: 2366 PKGNRG-DSIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVNQDTFGRMRDV 2424

Query: 638  VVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQ-- 695
            V+ +++ L+  E     P  +   VV Y++    E   +R    +    L + IK+LQ  
Sbjct: 2425 VLSIVNDLTIAE--SNCPRGARVAVVTYNNEVTTE---IRFADSKRKSVLLDKIKNLQVA 2479

Query: 696  WMAGGTFTGEALQYTRDQLLPPSPNNRIALVITDGRSDTQRDTTPLNVLCSPGIQVVSVG 755
              +       A+ +          N  +   +    S+T    +P   L    +++   G
Sbjct: 2480 LTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTRASP--QLREAVLKLSDAG 2537

Query: 756  IKDVFDFIPGSDQLNVISCQGLAPSQGRPGLSLVKENYAELLEDAFLKNV-TAQICIDKK 814
            I  +F       QL       L  +    G +LV     +L +  FL+NV T  +C+D  
Sbjct: 2538 ITPLFLTRQEDRQL----INALQINNTAVGHALVLPAGRDLTD--FLENVLTCHVCLDIC 2591

Query: 815  CPDYTCPITFSSPA-------------DITILLDGSASVGSHNFDTTKRFAKRLAERF-L 860
              D +C      P+             D+  +LD + +     F+  K++   L  +  +
Sbjct: 2592 NIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDM 2651

Query: 861  TAGRTDPAHDVRVAVVQYSGTGQQRPERASLQ------FLQNYTALASAVD----AMDFI 910
            +       H  RVAVVQ++ +  +  + AS+        L +Y +    VD     M  +
Sbjct: 2652 SPDPKASQHFARVAVVQHAPS--ESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQL 2709

Query: 911  NDATDVNDALGY-VTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQEAQRAGIEI 969
                 +  A+ Y +   +  A +    K ++L   G          ++ + +A+  G   
Sbjct: 2710 QGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFF 2769

Query: 970  FVVVVGRQVN 979
             V+ +GR+VN
Sbjct: 2770 VVLGIGRKVN 2779



 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 97/372 (26%), Positives = 141/372 (37%), Gaps = 54/372 (14%)

Query: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQS--YAGVVQYSHSQMQE 672
           D++F++D S ++GL NF   +DF+ KVI RL        E GQ      V QY+ +   E
Sbjct: 445 DIVFLVDGSSALGLANFNAIRDFIAKVIQRL--------EIGQDLIQVAVAQYADTVRPE 496

Query: 673 HVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNRIA------LV 726
                 P+ R V      +K L   A   +TG AL + R+ L   S   R A      LV
Sbjct: 497 FYFNTHPTKREVITAVRKMKPLDGSA--LYTGSALDFVRNNLFTSSAGYRAAEGIPKLLV 554

Query: 727 ITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGL 786
           +  G       + P   L    I   ++G K       G+DQ        L        L
Sbjct: 555 LITGGKSLDEISQPAQELKRSSIMAFAIGNK-------GADQAE------LEEIAFDSSL 601

Query: 787 SLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHNFD 846
             +   +        L  + A +      P+       S+  DI  LLDGSA+VG  NF 
Sbjct: 602 VFIPAEFRAAPLQGMLPGLLAPLRTLSGTPE-----VHSNKRDIIFLLDGSANVGKTNFP 656

Query: 847 TTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASAVDA 906
             + F   L    L  G      ++RV +VQ+S T        SL   Q  + +   +  
Sbjct: 657 YVRDFVMNLVNS-LDIGN----DNIRVGLVQFSDT---PVTEFSLNTYQTKSDILGHLRQ 708

Query: 907 MDFI-NDATDVNDALGYV-TRFYREASSGAAKKR----LLLFSDGNSQGATPAAIEKAVQ 960
           +        +   AL YV    + EA     ++     LLL + G S+     +  +A  
Sbjct: 709 LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSED----SYLQAAN 764

Query: 961 EAQRAGIEIFVV 972
              RAGI  F V
Sbjct: 765 ALTRAGILTFCV 776



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 84/349 (24%), Positives = 147/349 (42%), Gaps = 45/349 (12%)

Query: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674
           D++F++DSS +IG ++F++ ++F+  V+  L+  E         +  +VQ++ +    H 
Sbjct: 39  DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGE------NDFHFALVQFNGN---PHT 89

Query: 675 SLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNR-------IALVI 727
                + R  QE+   I ++ ++ G   TG+ L+Y     L  +  +R       + +V+
Sbjct: 90  EFLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVL 149

Query: 728 TDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLS 787
           TDG S       P   L S  + V ++G++D          L  I+ + L          
Sbjct: 150 TDGHSKDGL-ALPSAELKSADVNVFAIGVEDA-----DEGALKEIASEPLNMHM------ 197

Query: 788 LVKENYAEL--LEDAFLKNVTAQICIDKKCPDYTC-PITFSSPADITILLDGSASVGSHN 844
              EN+  L  +    +  V + +  ++     T   IT    ADI  L+DGS + GS N
Sbjct: 198 FNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVN 257

Query: 845 FDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASAV 904
           F     F   L E+ L  G       +RV VVQ+S    +     SL        +  AV
Sbjct: 258 FAVILDFLVNLLEK-LPIG----TQQIRVGVVQFS---DEPRTMFSLDTYSTKAQVLGAV 309

Query: 905 DAMDFI-NDATDVNDALGYVTRFYREASSGAAKKR-----LLLFSDGNS 947
            A+ F   +  ++  AL +V   +   + G+  +      L+L S G S
Sbjct: 310 KALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPS 358



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 70/305 (22%), Positives = 124/305 (40%), Gaps = 44/305 (14%)

Query: 615  DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674
            D++F++DSSE +    F   +DFV +++ RL+        P +   GVVQ+S+    E  
Sbjct: 1436 DIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLN------IGPSKVRVGVVQFSNDVFPE-- 1487

Query: 675  SLRSPSIRNVQELKEAIKSLQWMAGGTF-TGEALQYTRDQLLPPSPNNRIA------LVI 727
                 + R+   + +AI+ L+   G    TG+AL++    L   S  +RI       LV+
Sbjct: 1488 -FYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVL 1546

Query: 728  TDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLS 787
              G       +    V+ S GI  + VG +++        +L  I+          P L 
Sbjct: 1547 VLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNI-----DRTELQTIT--------NDPRLV 1593

Query: 788  LVKENYAEL--LEDAFLKNVTAQICIDKKCPDYTCPIT--FSSPADITILLDGSASVGSH 843
                 + EL  +E+  + +              T P +      ADI  LLDGS +    
Sbjct: 1594 FTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRD 1653

Query: 844  NFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASA 903
            +F    RF   + +     G       ++V +VQY+       +     FL++++     
Sbjct: 1654 SFQEVLRFVSEIVDTVYEDG-----DSIQVGLVQYNS------DPTDEFFLKDFSTKRQI 1702

Query: 904  VDAMD 908
            +DA++
Sbjct: 1703 IDAIN 1707



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 89/373 (23%), Positives = 151/373 (40%), Gaps = 47/373 (12%)

Query: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674
           D++F++D S + G  NF +  DF+V ++++L           Q   GVVQ+S  + +   
Sbjct: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKL------PIGTQQIRVGVVQFS-DEPRTMF 294

Query: 675 SLRSPSIRNVQELKEAIKSLQWMAGGTFT--GEALQYTRDQLLPPSPNNRIALVITDGRS 732
           SL + S +   ++  A+K+L + AGG     G AL +  +     +  +R+         
Sbjct: 295 SLDTYSTK--AQVLGAVKALGF-AGGELANIGLALDFVVENHFTRAGGSRV--------- 342

Query: 733 DTQRDTTPLNVLCSPG-------IQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPG 785
             +     + VL S G         VV++    VF F  G+   +    Q +A       
Sbjct: 343 --EEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVF 400

Query: 786 LSLVKENYAELLEDAFLKNV-TAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHN 844
                 ++ +L E      V  AQ  I  K P     +   +  DI  L+DGS+++G  N
Sbjct: 401 TVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLAN 460

Query: 845 FDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASAV 904
           F+  + F  ++ +R L  G+      ++VAV QY+ T   RPE            + +  
Sbjct: 461 FNAIRDFIAKVIQR-LEIGQ----DLIQVAVAQYADT--VRPEFYFNTHPTKREVITAVR 513

Query: 905 DAMDFINDATDVNDALGYVTRFYREASSG-----AAKKRLLLFSDGNSQGATPAAIEKAV 959
                   A     AL +V      +S+G        K L+L + G S       I +  
Sbjct: 514 KMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLD----EISQPA 569

Query: 960 QEAQRAGIEIFVV 972
           QE +R+ I  F +
Sbjct: 570 QELKRSSIMAFAI 582



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 89/358 (24%), Positives = 148/358 (41%), Gaps = 55/358 (15%)

Query: 612  GPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQ 671
            G  D++F++D S+S G + F+  +  + +++D L     V F+  +    V+Q+S     
Sbjct: 1230 GKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLD----VGFDTTR--VAVIQFSDDPKV 1282

Query: 672  EHVSLRSPSIRNVQELKEAIKSLQWMAGGTFT-GEALQYTRDQLLPPSPNNRIA------ 724
            E + L + S ++  E++ A++ L+   G     G AL+Y    +      +RI       
Sbjct: 1283 EFL-LNAHSSKD--EVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQF 1339

Query: 725  -LVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGR 783
             ++I+ G+SD + D         P +++   G+   F     +DQ  ++    L+P    
Sbjct: 1340 LVLISSGKSDDEVD--------DPAVELKQFGVAP-FTIARNADQEELVKIS-LSPEYV- 1388

Query: 784  PGLSLVKENYAELLEDAFLKNVTA----QICIDKKCPDYTCPITFSSPADITILLDGSAS 839
               S+        LE   L  +T     QI        Y  P   S  ADI  L+D S  
Sbjct: 1389 --FSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEG 1446

Query: 840  VGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTA 899
            V    F   + F  R+  R L  G +     VRV VVQ+S      PE     +L+ Y +
Sbjct: 1447 VRPDGFAHIRDFVSRIVRR-LNIGPS----KVRVGVVQFS--NDVFPE----FYLKTYRS 1495

Query: 900  LASAVDAMDFI----NDATDVNDALGYVTR--FYREASS---GAAKKRLLLFSDGNSQ 948
             A  +DA+  +        +   AL +V R  F + A S       + L+L   G SQ
Sbjct: 1496 QAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQ 1553



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 65/275 (23%), Positives = 112/275 (40%), Gaps = 42/275 (15%)

Query: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674
           D++F+LD S ++G  NF   +DFV+ +++ L               G+VQ+S + + E  
Sbjct: 639 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD------IGNDNIRVGLVQFSDTPVTE-F 691

Query: 675 SLRSPSIRNVQELKEAIKSLQWMAG-GTFTGEALQYTRDQLLPPSPNNRI-------ALV 726
           SL +   ++  ++   ++ LQ   G G  TG AL Y        +  +RI        L+
Sbjct: 692 SLNTYQTKS--DILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLL 749

Query: 727 ITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGL 786
           +T G+S+        N L   GI            F  G+ Q N    + +A     P L
Sbjct: 750 LTAGQSEDSY-LQAANALTRAGI----------LTFCVGASQANKAELEQIA---FNPSL 795

Query: 787 SLVKENYAEL--LEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHN 844
             + ++++ L  L    ++ +T  +    +      P    S  DI  L DGSA++    
Sbjct: 796 VYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQP---ESKRDILFLFDGSANLVG-Q 851

Query: 845 FDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYS 879
           F   + F  ++ +              R+AV QYS
Sbjct: 852 FPVVRDFLYKIIDEL-----NVKPEGTRIAVAQYS 881



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 87/396 (21%), Positives = 160/396 (40%), Gaps = 46/396 (11%)

Query: 615  DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQS-YAGVVQYSHSQMQEH 673
            D++F+LD S +    +F+    FV +++D +       +E G S   G+VQY +S   + 
Sbjct: 1639 DIVFLLDGSINFRRDSFQEVLRFVSEIVDTV-------YEDGDSIQVGLVQY-NSDPTDE 1690

Query: 674  VSLRSPSIRNVQELKEAIKSLQWMAG-GTFTGEALQYTRDQLLPPSPNNR-------IAL 725
              L+  S +  +++ +AI  + +  G    T   L++ R     P   +R       IA 
Sbjct: 1691 FFLKDFSTK--RQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAF 1748

Query: 726  VITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPG 785
            VIT G+S        L  L   G++V +VG++++     G    N  +   +   Q    
Sbjct: 1749 VITGGKSVEDAQDVSL-ALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQ---E 1804

Query: 786  LSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSAS----VG 841
            LS + E   E L DA  + +         CP  T     +   D+ +  DGS      V 
Sbjct: 1805 LSELSEQVLETLHDAMHETL---------CPGVT-DAAKACNLDVILGFDGSRDQNVFVA 1854

Query: 842  SHNFDT-TKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTAL 900
               F++       R+++    +     +  VRV+VV  + +G       +  F +    +
Sbjct: 1855 QKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVE----AFDFDEYQPEM 1910

Query: 901  ASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQ 960
                  M   +      D L      +R++S  + K  ++ F+DG       A + +A +
Sbjct: 1911 LEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVKV-VIHFTDG--ADGDLADLHRASE 1967

Query: 961  EAQRAGIEIFVVV-VGRQVNEPHIRVLVTGKTAEYD 995
              ++ G+   ++V + R VN   +  L  G+   YD
Sbjct: 1968 NLRQEGVRALILVGLERVVNLERLMHLEFGRGFMYD 2003



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 38/169 (22%), Positives = 75/169 (44%), Gaps = 20/169 (11%)

Query: 614  IDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEH 673
            ID+ F+LDS+E+  L  F   K ++  ++ +L      K     +   VVQ++ S+  ++
Sbjct: 2618 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2677

Query: 674  VSLRSPSIR-------NVQELKEAI-KSLQWMAGGTFTGEALQYTRDQLLPPSPNNR--- 722
             S+    +        + ++L + + + +  + G    G A++YT + +   +PN R   
Sbjct: 2678 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLK 2737

Query: 723  -IALVITDGRSDTQRDTTP---LNVLCSPGIQVV-----SVGIKDVFDF 762
             + L++T    + Q +      L   C     VV      V IK+V+ F
Sbjct: 2738 IVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTF 2786



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 33/154 (21%), Positives = 66/154 (42%), Gaps = 21/154 (13%)

Query: 828 ADITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPE 887
           ADI  L+D S ++G  +F   + F   +  + L  G     +D   A+VQ++G       
Sbjct: 38  ADIIFLVDSSWTIGEEHFQLVREFLYDVV-KSLAVGE----NDFHFALVQFNGNPH---T 89

Query: 888 RASLQFLQNYTALASAVDAMDFINDATDVNDALGYVTRFYREASSGA-----AKKRLLLF 942
              L   +    + S +  M +I         L Y+ + +   ++G+       + +++ 
Sbjct: 90  EFLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVL 149

Query: 943 SDGNSQG--ATPAAIEKAVQEAQRAGIEIFVVVV 974
           +DG+S+   A P+A      E + A + +F + V
Sbjct: 150 TDGHSKDGLALPSA------ELKSADVNVFAIGV 177


>gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo
            sapiens]
          Length = 2570

 Score =  335 bits (859), Expect = 1e-91
 Identities = 252/790 (31%), Positives = 359/790 (45%), Gaps = 72/790 (9%)

Query: 235  IVDMIKNNVEQVCCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP 294
            + + + N  E+ CC   C+   G  G RG  G  G +G PG  G +G  GD G PG+ GP
Sbjct: 1410 LAEQLDNIAEKACCGVPCK-CSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGP 1468

Query: 295  VGY---QGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGF 351
             G    QG +G  G RG KGSRG  G KGE G+ G+DG+DG  G+ G PG  G KG+PG 
Sbjct: 1469 PGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGR 1528

Query: 352  DGIQGPPGPKGDPGAFGLKGEKGEPGAD----GEAGRPGSSGPSGDEGQPGEPGPPGEKG 407
             G +GP G KG+ G  G++G+ G PG D    G  G  G  GP G  G+ G PG PGE G
Sbjct: 1529 RGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETG 1588

Query: 408  EAGDEGNPGPDGAPGERGGPG------ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVG 461
            + G  G  GP GA G +GGPG      E+G RG  G  GP G PG  G QG  G  G  G
Sbjct: 1589 KNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGG 1648

Query: 462  VPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGF 521
              G PGE G  GP G +G+ G PG +G  G  GP G  GD G  G   E      G  GF
Sbjct: 1649 AAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGF 1708

Query: 522  PGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQG 581
            PG+PG  GN G PG+NGT G  G++G  G +G P          G+ G KG  G  GP G
Sbjct: 1709 PGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPP----------GIVGQKGDPGYPGPAG 1758

Query: 582  PPGHQGPPGPDECEILDIIMKMCSCC----ECKCGPIDLLFVLDSSESIGLQNFEIAKDF 637
            P G++G    D+C ++  I   C CC    EC   P +L F LD+SE +    F   +D 
Sbjct: 1759 PKGNRG-DSIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVNQDTFGRMRDV 1817

Query: 638  VVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQ-- 695
            V+ +++ L+  E     P  +   VV Y++    E   +R    +    L + IK+LQ  
Sbjct: 1818 VLSIVNDLTIAE--SNCPRGARVAVVTYNNEVTTE---IRFADSKRKSVLLDKIKNLQVA 1872

Query: 696  WMAGGTFTGEALQYTRDQLLPPSPNNRIALVITDGRSDTQRDTTPLNVLCSPGIQVVSVG 755
              +       A+ +          N  +   +    S+T    +P   L    +++   G
Sbjct: 1873 LTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTRASP--QLREAVLKLSDAG 1930

Query: 756  IKDVFDFIPGSDQLNVISCQGLAPSQGRPGLSLVKENYAELLEDAFLKNV-TAQICIDKK 814
            I  +F       QL       L  +    G +LV     +L +  FL+NV T  +C+D  
Sbjct: 1931 ITPLFLTRQEDRQL----INALQINNTAVGHALVLPAGRDLTD--FLENVLTCHVCLDIC 1984

Query: 815  CPDYTCPITFSSPA-------------DITILLDGSASVGSHNFDTTKRFAKRLAERF-L 860
              D +C      P+             D+  +LD + +     F+  K++   L  +  +
Sbjct: 1985 NIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDM 2044

Query: 861  TAGRTDPAHDVRVAVVQYSGTGQQRPERASLQ------FLQNYTALASAVD----AMDFI 910
            +       H  RVAVVQ++ +  +  + AS+        L +Y +    VD     M  +
Sbjct: 2045 SPDPKASQHFARVAVVQHAPS--ESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQL 2102

Query: 911  NDATDVNDALGY-VTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQEAQRAGIEI 969
                 +  A+ Y +   +  A +    K ++L   G          ++ + +A+  G   
Sbjct: 2103 QGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFF 2162

Query: 970  FVVVVGRQVN 979
             V+ +GR+VN
Sbjct: 2163 VVLGIGRKVN 2172



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 69/273 (25%), Positives = 101/273 (36%), Gaps = 44/273 (16%)

Query: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQS--YAGVVQYSHSQMQE 672
           D++F++D S ++GL NF   +DF+ KVI RL        E GQ      V QY+ +   E
Sbjct: 38  DIVFLVDGSSALGLANFNAIRDFIAKVIQRL--------EIGQDLIQVAVAQYADTVRPE 89

Query: 673 HVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNRIA------LV 726
                 P+ R V      +K L   A   +TG AL + R+ L   S   R A      LV
Sbjct: 90  FYFNTHPTKREVITAVRKMKPLDGSA--LYTGSALDFVRNNLFTSSAGYRAAEGIPKLLV 147

Query: 727 ITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGL 786
           +  G       + P   L    I   ++G K       G+DQ        L        L
Sbjct: 148 LITGGKSLDEISQPAQELKRSSIMAFAIGNK-------GADQAE------LEEIAFDSSL 194

Query: 787 SLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHNFD 846
             +   +        L  + A +      P+        S  DI  L DGSA++    F 
Sbjct: 195 VFIPAEFRAAPLQGMLPGLLAPLRTLSGTPE-------ESKRDILFLFDGSANLVG-QFP 246

Query: 847 TTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYS 879
             + F  ++ +              R+AV QYS
Sbjct: 247 VVRDFLYKIIDEL-----NVKPEGTRIAVAQYS 274



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 88/335 (26%), Positives = 135/335 (40%), Gaps = 60/335 (17%)

Query: 615 DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYS-----HSQ 669
           D+LF+ D S ++ +  F + +DF+ K+ID L+       +P  +   V QYS      S+
Sbjct: 230 DILFLFDGSANL-VGQFPVVRDFLYKIIDELN------VKPEGTRIAVAQYSDDVKVESR 282

Query: 670 MQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFT-GEALQYTRDQLLPPSPNNRI----- 723
             EH S   P I N+      +K ++   G     G AL Y +  +   S  +RI     
Sbjct: 283 FDEHQS--KPEILNL------VKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVL 334

Query: 724 --ALVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQ 781
              +++  GRS  + D  P + L   G+       K+     P   +  V+S   +  ++
Sbjct: 335 QFLVLLVAGRSSDRVD-GPASNLKQSGVVPFIFQAKNA---DPAELEQIVLSPAFILAAE 390

Query: 782 GRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASVG 841
             P +  +      LL                K      P   S   D+  LLDGS  V 
Sbjct: 391 SLPKIGDLHPQIVNLL----------------KSVHNGAPAPVSGEKDVVFLLDGSEGVR 434

Query: 842 SHNFDTTKRFAKRLAERFLTAGRTDPAHD-VRVAVVQYSGTGQQRPERASLQFLQNYTAL 900
           S  F   K F +R+ E        D   D VRVAVVQYS   + RPE   L    N   +
Sbjct: 435 S-GFPLLKEFVQRVVESL------DVGQDRVRVAVVQYS--DRTRPE-FYLNSYMNKQDV 484

Query: 901 ASAVDAMDFINDAT-DVNDALGYVTRFYREASSGA 934
            +AV  +  +   T +   AL +V R    +S+G+
Sbjct: 485 VNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGS 519



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 70/305 (22%), Positives = 124/305 (40%), Gaps = 44/305 (14%)

Query: 615  DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHV 674
            D++F++DSSE +    F   +DFV +++ RL+        P +   GVVQ+S+    E  
Sbjct: 829  DIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLN------IGPSKVRVGVVQFSNDVFPE-- 880

Query: 675  SLRSPSIRNVQELKEAIKSLQWMAGGTF-TGEALQYTRDQLLPPSPNNRIA------LVI 727
                 + R+   + +AI+ L+   G    TG+AL++    L   S  +RI       LV+
Sbjct: 881  -FYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVL 939

Query: 728  TDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLS 787
              G       +    V+ S GI  + VG +++        +L  I+          P L 
Sbjct: 940  VLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNI-----DRTELQTIT--------NDPRLV 986

Query: 788  LVKENYAEL--LEDAFLKNVTAQICIDKKCPDYTCPIT--FSSPADITILLDGSASVGSH 843
                 + EL  +E+  + +              T P +      ADI  LLDGS +    
Sbjct: 987  FTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRD 1046

Query: 844  NFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASA 903
            +F    RF   + +     G       ++V +VQY+       +     FL++++     
Sbjct: 1047 SFQEVLRFVSEIVDTVYEDG-----DSIQVGLVQYNS------DPTDEFFLKDFSTKRQI 1095

Query: 904  VDAMD 908
            +DA++
Sbjct: 1096 IDAIN 1100



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 89/358 (24%), Positives = 148/358 (41%), Gaps = 55/358 (15%)

Query: 612 GPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQ 671
           G  D++F++D S+S G + F+  +  + +++D L     V F+  +    V+Q+S     
Sbjct: 623 GKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLD----VGFDTTR--VAVIQFSDDPKV 675

Query: 672 EHVSLRSPSIRNVQELKEAIKSLQWMAGGTFT-GEALQYTRDQLLPPSPNNRIA------ 724
           E + L + S ++  E++ A++ L+   G     G AL+Y    +      +RI       
Sbjct: 676 EFL-LNAHSSKD--EVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQF 732

Query: 725 -LVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGR 783
            ++I+ G+SD + D         P +++   G+   F     +DQ  ++    L+P    
Sbjct: 733 LVLISSGKSDDEVD--------DPAVELKQFGVAP-FTIARNADQEELVKIS-LSPEYV- 781

Query: 784 PGLSLVKENYAELLEDAFLKNVTA----QICIDKKCPDYTCPITFSSPADITILLDGSAS 839
              S+        LE   L  +T     QI        Y  P   S  ADI  L+D S  
Sbjct: 782 --FSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEG 839

Query: 840 VGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTA 899
           V    F   + F  R+  R L  G +     VRV VVQ+S      PE     +L+ Y +
Sbjct: 840 VRPDGFAHIRDFVSRIVRR-LNIGPS----KVRVGVVQFS--NDVFPE----FYLKTYRS 888

Query: 900 LASAVDAMDFI----NDATDVNDALGYVTR--FYREASS---GAAKKRLLLFSDGNSQ 948
            A  +DA+  +        +   AL +V R  F + A S       + L+L   G SQ
Sbjct: 889 QAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQ 946



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 87/396 (21%), Positives = 160/396 (40%), Gaps = 46/396 (11%)

Query: 615  DLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQS-YAGVVQYSHSQMQEH 673
            D++F+LD S +    +F+    FV +++D +       +E G S   G+VQY +S   + 
Sbjct: 1032 DIVFLLDGSINFRRDSFQEVLRFVSEIVDTV-------YEDGDSIQVGLVQY-NSDPTDE 1083

Query: 674  VSLRSPSIRNVQELKEAIKSLQWMAG-GTFTGEALQYTRDQLLPPSPNNR-------IAL 725
              L+  S +  +++ +AI  + +  G    T   L++ R     P   +R       IA 
Sbjct: 1084 FFLKDFSTK--RQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAF 1141

Query: 726  VITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPG 785
            VIT G+S        L  L   G++V +VG++++     G    N  +   +   Q    
Sbjct: 1142 VITGGKSVEDAQDVSL-ALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQ---E 1197

Query: 786  LSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSAS----VG 841
            LS + E   E L DA  + +         CP  T     +   D+ +  DGS      V 
Sbjct: 1198 LSELSEQVLETLHDAMHETL---------CPGVT-DAAKACNLDVILGFDGSRDQNVFVA 1247

Query: 842  SHNFDT-TKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTAL 900
               F++       R+++    +     +  VRV+VV  + +G       +  F +    +
Sbjct: 1248 QKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVE----AFDFDEYQPEM 1303

Query: 901  ASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQ 960
                  M   +      D L      +R++S  + K  ++ F+DG       A + +A +
Sbjct: 1304 LEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVKV-VIHFTDG--ADGDLADLHRASE 1360

Query: 961  EAQRAGIEIFVVV-VGRQVNEPHIRVLVTGKTAEYD 995
              ++ G+   ++V + R VN   +  L  G+   YD
Sbjct: 1361 NLRQEGVRALILVGLERVVNLERLMHLEFGRGFMYD 1396



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 38/169 (22%), Positives = 75/169 (44%), Gaps = 20/169 (11%)

Query: 614  IDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEH 673
            ID+ F+LDS+E+  L  F   K ++  ++ +L      K     +   VVQ++ S+  ++
Sbjct: 2011 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2070

Query: 674  VSLRSPSIR-------NVQELKEAI-KSLQWMAGGTFTGEALQYTRDQLLPPSPNNR--- 722
             S+    +        + ++L + + + +  + G    G A++YT + +   +PN R   
Sbjct: 2071 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLK 2130

Query: 723  -IALVITDGRSDTQRDTTP---LNVLCSPGIQVV-----SVGIKDVFDF 762
             + L++T    + Q +      L   C     VV      V IK+V+ F
Sbjct: 2131 IVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTF 2179



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 39/149 (26%), Positives = 63/149 (42%), Gaps = 16/149 (10%)

Query: 829 DITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPER 888
           DI  L+DGS+++G  NF+  + F  ++ +R L  G+      ++VAV QY+ T   RPE 
Sbjct: 38  DIVFLVDGSSALGLANFNAIRDFIAKVIQR-LEIGQ----DLIQVAVAQYADT--VRPEF 90

Query: 889 ASLQFLQNYTALASAVDAMDFINDATDVNDALGYVTRFYREASSG-----AAKKRLLLFS 943
                      + +          A     AL +V      +S+G        K L+L +
Sbjct: 91  YFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLIT 150

Query: 944 DGNSQGATPAAIEKAVQEAQRAGIEIFVV 972
            G S       I +  QE +R+ I  F +
Sbjct: 151 GGKSLD----EISQPAQELKRSSIMAFAI 175


>gi|154759255 collagen, type XXVIII precursor [Homo sapiens]
          Length = 1125

 Score =  333 bits (855), Expect = 4e-91
 Identities = 217/538 (40%), Positives = 287/538 (53%), Gaps = 72/538 (13%)

Query: 257 GPPGLRGDPGFEGERGKPG--LPGEKGEAGDPGRPGDLGPVGYQGM--KGEKGSRGEKGS 312
           G PG RG  G  GERG PG   PG KGE G  G     GP G QG+  KGEKG  G  G 
Sbjct: 386 GQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEG---PTGPQGLQGLSIKGEKGDIGPVGP 442

Query: 313 RGPKGYKG--EKGKRGIDGVDGVKGEMGYPG--LPGCKGSPGFDGIQGP--------PGP 360
           +GP G  G   +G++GI G  G  G  G  G  LPG KG  G  G  GP         GP
Sbjct: 443 QGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGP 502

Query: 361 KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA 420
           KG+PG+ GL G+ G PG DG AG+ G +G  G  G  G PG  G+ G  GDEG  G  G 
Sbjct: 503 KGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK-GQPGPKGDEGKKGSKGN 561

Query: 421 PGERGGPGERGPRGTPGTRGPRGDPGEA--GPQGDQGREGPVGVPGDPGEAGPI--GPKG 476
            G+RG PG  GP+G PG  GP G PG +  GP G +G  G  G+PG  GE G    GPKG
Sbjct: 562 QGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKG 621

Query: 477 YRGDEGP-----------PGSEGARGAPGPAGP-----------PGDPGLMGERGEDGPA 514
            +G  GP           PG  G RG PGP GP            G+PG+ G  G  GP 
Sbjct: 622 VQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPR 681

Query: 515 GNGTEG---------FPGFPGYPG--NRGAPGINGTKGYPGLKGDEGEA--GDPGD--DN 559
           G GT+G          PG PG PG  ++G  G  G +G+PG KG  G    G  G+  + 
Sbjct: 682 GVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGER 741

Query: 560 NDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPDECEILDIIMKMCSCC-ECKCGPIDLLF 618
            D+  +G KG  G  G  G QG  G +G  G  + EI+ +I ++C C  +CK  P++L+F
Sbjct: 742 GDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLITEICGCGPKCKETPLELVF 801

Query: 619 VLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHVSLRS 678
           V+DSSES+G +NF+I K+FV  + DR++ D         +  G++ YSH ++++  +L+ 
Sbjct: 802 VIDSSESVGPENFQIIKNFVKTMADRVALDLAT------ARIGIINYSH-KVEKVANLKQ 854

Query: 679 PSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPN-NRIALVITDGRSDTQ 735
            S ++  + K A+ ++Q++  GT+T  ALQ   D      P   ++ALVITDG++D++
Sbjct: 855 FSSKD--DFKLAVDNMQYLGEGTYTATALQAANDMFEDARPGVKKVALVITDGQTDSR 910



 Score =  307 bits (786), Expect = 4e-83
 Identities = 216/593 (36%), Positives = 291/593 (49%), Gaps = 89/593 (15%)

Query: 34  CPVDLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLRDRYYRCD--RNLVWNA--G 89
           C +D+ F++D+SES  +      AL DK K F    +D+L D+ ++    R+L ++    
Sbjct: 45  CFIDIVFIVDSSESSKI------ALFDKQKDF----VDSLSDKIFQLTPGRSLEYDIKLA 94

Query: 90  ALHYSDEVEIIQGLTRMPGGRDALKSSVDAVKYFGKGTYTDCAIKKGLEQLLVGGSHLKE 149
           AL +S  V+I    +         K  V ++   G+GT++  AI     +LL        
Sbjct: 95  ALQFSSSVQIDPPFSSWKD-LQTFKQKVKSMNLIGQGTFSYYAISNAT-RLLKREGRKDG 152

Query: 150 NKYLIVVTDG--HPLEGYKEPCGGLEDAVNEAKHLGVKVFSVAITPDHLEPRLSIIATDH 207
            K ++++TDG  HP    K P   ++    +A+  G+   ++A++    E +L +I+ D 
Sbjct: 153 VKVVLLMTDGIDHP----KNP--DVQSISEDARISGISFITIALSTVVNEAKLRLISGDS 206

Query: 208 TYRRNFTAADWGQSRDAEEAISQTIDTIVDMIKNNVEQVCCSFECQPARGPPGLRGDPGF 267
           +       +D              +D I D +    E+ C    C+  +G PG   DPG 
Sbjct: 207 SSEPTLLLSD-----------PTLVDKIQDRLDILFEKKCERKICECEKGDPG---DPGP 252

Query: 268 EGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGI 327
            G  G PG+ GE+G  G+PG               +KG  GE+G  G  GYKG+KG+RG 
Sbjct: 253 PGTHGNPGIKGERGPKGNPGN-------------AQKGEAGERGPGGIPGYKGDKGERGE 299

Query: 328 DGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGS 387
            G  G+KG+ G PG  G KG  G  GI GPP   GDPG  G +G KGEPG  G  G PG+
Sbjct: 300 CGKPGIKGDKGSPGPYGPKGPRGIQGITGPP---GDPGPKGFQGNKGEPGPPGPYGSPGA 356

Query: 388 --------SGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGE--RGPRGTPG 437
                    G  G EG+PG PGP G  GE G  G  GP+G PGERG PGE   GP+G  G
Sbjct: 357 PGIGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKG 415

Query: 438 TRGPRGD--------PGEAGPQGDQGREGPVGVP-----GDPGEAGPIGPKGYRG--DEG 482
           + GP G          GE G  G  G +GP+G+P     G+ G  GPIGP G +G   +G
Sbjct: 416 SEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQG 475

Query: 483 PPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTKG 541
            PGS+G  G  GP GP G  G+    G  GP G  G+ G PG PG PG  GA G  G  G
Sbjct: 476 LPGSKGEVGQMGPTGPRGPVGI----GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAG 531

Query: 542 YPGLKGDEGEAG----DPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
            PG +G EG  G     P  D      +G +G +G  GPEGP+G PG  GP G
Sbjct: 532 LPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFG 584



 Score =  115 bits (287), Expect = 3e-25
 Identities = 70/176 (39%), Positives = 85/176 (48%), Gaps = 30/176 (17%)

Query: 423 ERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEG 482
           E+G PG+ GP   PGT G  G  GE GP+G+ G        G+ GE GP G  GY+GD+G
Sbjct: 243 EKGDPGDPGP---PGTHGNPGIKGERGPKGNPGN----AQKGEAGERGPGGIPGYKGDKG 295

Query: 483 PPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGTKG 541
             G              G PG+ G++G  GP G  G  G  G  G PG+ G  G  G KG
Sbjct: 296 ERGE------------CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKG 343

Query: 542 YPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGP-----PGHQGPPGPD 592
            PG  G  G  G PG     I  +G+KG +G  G  G  GP     PG  GP GP+
Sbjct: 344 EPGPPGPYGSPGAPG-----IGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPE 394



 Score = 95.1 bits (235), Expect = 3e-19
 Identities = 56/115 (48%), Positives = 67/115 (58%), Gaps = 14/115 (12%)

Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGY--QGMKGEKGSRGEKGS 312
           A+G PG+RG PG  G RG  G  G KG+ G  G PG  GP GY  QG+KGE+G +G  G 
Sbjct: 665 AKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGP 723

Query: 313 RGPKGY-----KGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKG 362
           +G  G+     KGE G+RG  G  G KGE+G P      GSPG  G+QGP G  G
Sbjct: 724 KGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEP------GSPGKQGLQGPKGDLG 772



 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 48/107 (44%), Positives = 55/107 (51%), Gaps = 20/107 (18%)

Query: 487 EGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGN--RGAPGINGTKGYPG 544
           E  +G PG  GPPG  G  G +GE GP GN           PGN  +G  G  G  G PG
Sbjct: 241 ECEKGDPGDPGPPGTHGNPGIKGERGPKGN-----------PGNAQKGEAGERGPGGIPG 289

Query: 545 LKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
            KGD+GE G+ G         G+KG KG  GP GP+GP G QG  GP
Sbjct: 290 YKGDKGERGECGKP-------GIKGDKGSPGPYGPKGPRGIQGITGP 329



 Score = 63.9 bits (154), Expect = 7e-10
 Identities = 52/206 (25%), Positives = 92/206 (44%), Gaps = 19/206 (9%)

Query: 780 SQGRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSAS 839
           S G+ GL   K +   L ++  +K +T       KC +        +P ++  ++D S S
Sbjct: 758 SPGKQGLQGPKGDLG-LTKEEIIKLITEICGCGPKCKE--------TPLELVFVIDSSES 808

Query: 840 VGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTA 899
           VG  NF   K F K +A+R      T      R+ ++ YS    +  + A+L+   +   
Sbjct: 809 VGPENFQIIKNFVKTMADRVALDLAT-----ARIGIINYS---HKVEKVANLKQFSSKDD 860

Query: 900 LASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAV 959
              AVD M ++ + T    AL      + +A  G  KK  L+ +DG +       + + V
Sbjct: 861 FKLAVDNMQYLGEGTYTATALQAANDMFEDARPG-VKKVALVITDGQTDSRDKEKLTEVV 919

Query: 960 QEAQRAGIEIFVVVVGRQVNEPHIRV 985
           + A    +EIFV+ V ++ N+P+  +
Sbjct: 920 KNASDTNVEIFVIGVVKK-NDPNFEI 944



 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 9/199 (4%)

Query: 829  DITILLDGSASVGSHNFDTTKRFAKRLAERF--LTAGRTDPAHDVRVAVVQYSGTGQQRP 886
            DI  ++D S S     FD  K F   L+++   LT GR+   +D+++A +Q+S + Q  P
Sbjct: 48   DIVFIVDSSESSKIALFDKQKDFVDSLSDKIFQLTPGRS-LEYDIKLAALQFSSSVQIDP 106

Query: 887  ERASLQFLQNYTALASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGN 946
              +S + LQ +      V +M+ I   T    A+   TR  +        K +LL +DG 
Sbjct: 107  PFSSWKDLQTF---KQKVKSMNLIGQGTFSYYAISNATRLLKREGRKDGVKVVLLMTDGI 163

Query: 947  SQGATPAAIEKAVQEAQRAGIEIFVVVVGRQVNEPHIRVLVTGKTAEYDVAYGESHLFRV 1006
                 P  ++   ++A+ +GI    + +   VNE  +R++    ++E  +   +  L  V
Sbjct: 164  DHPKNP-DVQSISEDARISGISFITIALSTVVNEAKLRLISGDSSSEPTLLLSDPTL--V 220

Query: 1007 PSYQALLRGVFHQTVSRKV 1025
               Q  L  +F +   RK+
Sbjct: 221  DKIQDRLDILFEKKCERKI 239



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 57/225 (25%), Positives = 98/225 (43%), Gaps = 31/225 (13%)

Query: 614 IDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEH 673
           ID++F++DSSES  +  F+  KDFV    D LS D++ +  PG+S    ++ +  Q    
Sbjct: 47  IDIVFIVDSSESSKIALFDKQKDFV----DSLS-DKIFQLTPGRSLEYDIKLAALQFSSS 101

Query: 674 VSLRSP--SIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNN--RIALVITD 729
           V +  P  S +++Q  K+ +KS+  +  GTF+  A+      L      +  ++ L++TD
Sbjct: 102 VQIDPPFSSWKDLQTFKQKVKSMNLIGQGTFSYYAISNATRLLKREGRKDGVKVVLLMTD 161

Query: 730 G-----RSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRP 784
           G       D Q  +    +    GI  +++ +  V +      +L +IS      S   P
Sbjct: 162 GIDHPKNPDVQSISEDARI---SGISFITIALSTVVN----EAKLRLIS----GDSSSEP 210

Query: 785 GLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPAD 829
            L L      + ++D         I  +KKC    C      P D
Sbjct: 211 TLLLSDPTLVDKIQDRL------DILFEKKCERKICECEKGDPGD 249



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 50/187 (26%), Positives = 86/187 (45%), Gaps = 26/187 (13%)

Query: 32  QDCPVDLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLRDRYYRCDRNLVWNAGAL 91
           ++ P++L FV+D+SESV     P    +  +K+F K   D +               G +
Sbjct: 793 KETPLELVFVIDSSESVG----PENFQI--IKNFVKTMADRVALDLATA------RIGII 840

Query: 92  HYSDEVEIIQGLTRMPGGRDALKSSVDAVKYFGKGTYTDCAIKKGLEQLLVGGSHLKENK 151
           +YS +VE +  L +    +D  K +VD ++Y G+GTYT  A++   +        +K  K
Sbjct: 841 NYSHKVEKVANLKQF-SSKDDFKLAVDNMQYLGEGTYTATALQAANDMFEDARPGVK--K 897

Query: 152 YLIVVTDGHPLEGYKEPCGGLEDAVNEAKHLGVKVFSVAITPDH------LEPRLSIIAT 205
             +V+TDG      KE    L + V  A    V++F + +   +          +++IAT
Sbjct: 898 VALVITDGQTDSRDKEK---LTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIAT 954

Query: 206 D--HTYR 210
           D  H Y+
Sbjct: 955 DPEHVYQ 961


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  312 bits (800), Expect = 9e-85
 Identities = 182/379 (48%), Positives = 196/379 (51%), Gaps = 50/379 (13%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            RGPPGL G PG  G  G PG  G KG AG PG PG  G  G QGM GE   RG  GS GP
Sbjct: 683  RGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGE---RGGLGSPGP 739

Query: 316  KGYKGEKGKRGIDGVDGV---------------------KGEMGYPGLPGC---KGSPGF 351
            KG KGE G  G DGV G                      KGE G PGLPG    +GSPG 
Sbjct: 740  KGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGE 799

Query: 352  DGIQGPPGPKGDPGAFGL------KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGE 405
             G  GPPGP G PGA G       KGE+G PG  GE G PG +GP G  G  G PGP G 
Sbjct: 800  RGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGV 859

Query: 406  KGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGD 465
            KGE G  G PG  G PG RG PG  G  G PG  GP G PG+ GP G  G     G PG 
Sbjct: 860  KGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGN---TGAPGS 916

Query: 466  PGEAGPIGPKGYRGDEGPPGSEGARGAPGP---------AGPPGDPGLMGERGEDGPAG- 515
            PG +GP G  G  G++G PG++G  GAPGP          G  G PG+ G RG  GP G 
Sbjct: 917  PGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGV 976

Query: 516  NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDD---NNDIAPRGVKGAKG 572
             G  G PG  G  G RG PG  G  G  G  G+ G  G+PG D     D +P G KG +G
Sbjct: 977  KGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGG-KGDRG 1035

Query: 573  YRGPEGPQGPPGHQGPPGP 591
              G  G  G PGH GPPGP
Sbjct: 1036 ENGSPGAPGAPGHPGPPGP 1054



 Score =  304 bits (778), Expect = 3e-82
 Identities = 173/385 (44%), Positives = 195/385 (50%), Gaps = 50/385 (12%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            GPPG  G PG +GE G PGLPG  G  G PG  G+ GP G  G  G  G  GE G +G +
Sbjct: 768  GPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGER 827

Query: 317  GYKGEKGKRGIDGV---------------DGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361
            G  GEKG+ G  GV                GVKGE G PG PG  G PG  G+ GPPG  
Sbjct: 828  GAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSN 887

Query: 362  GDPGAFGLKGEKGEPGADGEAGR------PGSSGPSGDEGQPGEPGPPGEKGEAG----- 410
            G+PG  G  G  G+ G  G AG       PG SGP GD GQPGE G PG +G  G     
Sbjct: 888  GNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPL 947

Query: 411  -------------------DEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQ 451
                                 G+PGP G  GE G PG  G  G  G  GP+G PG AG  
Sbjct: 948  GIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTA 1007

Query: 452  GDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGED 511
            G+ GR+G  G  G PG  G  G KG RG+ G PG+ GA G PGP GP G  G  G+RGE 
Sbjct: 1008 GEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGES 1067

Query: 512  GPAG----NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGV 567
            GPAG     G  G  G PG  G RG  G  G +G  G+KG  G  G+PG   +   P G 
Sbjct: 1068 GPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSP-GPAGQ 1126

Query: 568  KGAKGYRGPEGPQGPPGHQGPPGPD 592
            +GA G  GP GP+GP G  GPPG D
Sbjct: 1127 QGAIGSPGPAGPRGPVGPSGPPGKD 1151



 Score =  302 bits (774), Expect = 9e-82
 Identities = 168/362 (46%), Positives = 191/362 (52%), Gaps = 41/362 (11%)

Query: 257 GPPGLRGDPGFEGE---RGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSR 313
           GPPG  G PG  G    +G PG PG+ G +G PG PG +GP G  G  GE G  G  G R
Sbjct: 183 GPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGER 242

Query: 314 G---PKGYKGE---------KGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361
           G   P G KG          KG RG DG +G KGE G PGL G  G PG +G  GP GP+
Sbjct: 243 GLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPR 302

Query: 362 GDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGE---------KGEAGDE 412
           G PG      E+G PG  G AG  G+ G  G +GQPG PGPPG          KGE G  
Sbjct: 303 GAPG------ERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPA 356

Query: 413 GNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPI 472
           G+PG +GAPG+RG PG   P+G  G +GP G PG  G  G +G  GP G+PG PG  G  
Sbjct: 357 GSPGSNGAPGQRGEPG---PQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGAR 413

Query: 473 GPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDG----PAGNGTEGFPGFPGYP 528
           GP G  G  G PG  G  G PG  G  G+PG  GERGE G    P   G +G  G PG P
Sbjct: 414 GPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEP 473

Query: 529 GNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGP 588
           G  G PG  G +G PG +G  G  G PG+      P G +GA G  GP G  G PG  G 
Sbjct: 474 GANGLPGAAGERGAPGFRGPAGPNGIPGEK----GPAGERGAPGPAGPRGAAGEPGRDGV 529

Query: 589 PG 590
           PG
Sbjct: 530 PG 531



 Score =  299 bits (765), Expect = 1e-80
 Identities = 173/367 (47%), Positives = 198/367 (53%), Gaps = 41/367 (11%)

Query: 255 ARGPPGLRG---DPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG 311
           A G PGLRG   +PG  G +G+PG  GE+GEAG PG PG  G  G  G  GE G+ G  G
Sbjct: 421 ANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPG 480

Query: 312 SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKG 371
           + G +G  G +G  G +G+ G KG  G  G PG  G  G     G PG  G PG  G++G
Sbjct: 481 AAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRG---AAGEPGRDGVPGGPGMRG 537

Query: 372 EKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGP---DGAP---GERG 425
             G PG  G  G+PG  G  G+ G+PG PGP G +G+ G  G PGP   DGAP   GERG
Sbjct: 538 MPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERG 597

Query: 426 GPGERGPRGTPGTR---GPRGDPGEAGPQGDQGREGPV------------GVPGDPGEAG 470
           GPG  GP+G PG     GP+G PG  GP GD+G  GP             G PG+ G+ G
Sbjct: 598 GPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPG 657

Query: 471 PIGPKGYRGDEGPPGSEGARGAPGPAGPP---GDPGLMGERGEDGPAGN----GTEGFPG 523
             GPKG  G  G PG +G  GAPG  GPP   G PGL G  G  GP G     G  G PG
Sbjct: 658 EPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPG 717

Query: 524 FPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPP 583
             G PG +G PG  G  G PG KGD+GE G PG D       GV G  G RGP GP GPP
Sbjct: 718 AAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGAD-------GVPGKDGPRGPTGPIGPP 770

Query: 584 GHQGPPG 590
           G  G PG
Sbjct: 771 GPAGQPG 777



 Score =  298 bits (762), Expect = 2e-80
 Identities = 171/354 (48%), Positives = 193/354 (54%), Gaps = 25/354 (7%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPG---DLGPVGYQGMKGEKGSRGEKGSR 313
           G  G RG+ G  G  G+PG PG  G AG PG PG   ++GP G  G  G  G RGE G +
Sbjct: 315 GAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQ 374

Query: 314 GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373
           G  G +G  G  GI+G  G KGEMG  G+PG   +PG  G +GPPGP G  GA GL+G  
Sbjct: 375 GHAGAQGPPGPPGINGSPGGKGEMGPAGIPG---APGLMGARGPPGPAGANGAPGLRGGA 431

Query: 374 GEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPG---ERGGPGER 430
           GEPG +G  G PG  G  G+ G PG PG  GE G+ G  G PG +G PG   ERG PG R
Sbjct: 432 GEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFR 491

Query: 431 ---GPRGTPGTRGP---RGDPGEAGPQGDQGREGPVGVPGDPGEAG----PIGPKGYRGD 480
              GP G PG +GP   RG PG AGP+G  G  G  GVPG PG  G    P GP G  G 
Sbjct: 492 GPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGP-GSDGK 550

Query: 481 EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN----GTEGFPGFPGYPGNRGAPGI 536
            GPPGS+G  G PGP GP G  G  G  G  GP GN    G  G  G PG PG +G PG 
Sbjct: 551 PGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGK 610

Query: 537 NGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           NG  G  G  G  G  GD G D     P+G++G  G  GP G  G PG  GP G
Sbjct: 611 NGETGPQGPPGPTGPGGDKG-DTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKG 663



 Score =  298 bits (762), Expect = 2e-80
 Identities = 165/372 (44%), Positives = 197/372 (52%), Gaps = 39/372 (10%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
           GPPG+ G PG +GE G  G+PG  G  G  G PG  G  G  G++G  G  G+ G++G  
Sbjct: 384 GPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEP 443

Query: 317 GYKGEKGKRGIDGVDGVKGE------------MGYPGLPGCKGSPGF---------DGIQ 355
           G +GE+G+ GI GV G KGE             G PG  G +G+PGF          G +
Sbjct: 444 GPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEK 503

Query: 356 GPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPG---EPGPPGEKGEAGDE 412
           GP G +G PG  G +G  GEPG DG  G PG  G  G  G PG   +PGPPG +GE+G  
Sbjct: 504 GPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRP 563

Query: 413 GNPGPDGA---PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEA 469
           G PGP G    PG  G PG +G  G PG  G RG PG  GPQG  G+ G  G  G PG  
Sbjct: 564 GPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPG-- 621

Query: 470 GPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDG-------PAGNGTEGFP 522
            P GP G +GD GPPG +G +G PG  GPPG+ G  GE G  G       P G G  G P
Sbjct: 622 -PTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAP 680

Query: 523 GFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAP--RGVKGAKGYRGPEGPQ 580
           G  G PG  GAPG+ G  G PG +G +G AG PG       P  +G+ G +G  G  GP+
Sbjct: 681 GERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPK 740

Query: 581 GPPGHQGPPGPD 592
           G  G  G PG D
Sbjct: 741 GDKGEPGGPGAD 752



 Score =  298 bits (762), Expect = 2e-80
 Identities = 169/354 (47%), Positives = 193/354 (54%), Gaps = 23/354 (6%)

Query: 257 GPPGLRGD---PGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSR 313
           GP G +GD   PG +G +G PG  G  GE G PG PG  G  G  G  G KG  G  G R
Sbjct: 624 GPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGER 683

Query: 314 GPKGYKGEKGKRG---IDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370
           GP G  G  G RG     G +G KG  G PG PG  G+PG  G+ G  G  G PG  G K
Sbjct: 684 GPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDK 743

Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP---GPDGAPGERGGP 427
           GE G PGADG  G+ G  GP+G  G PG  G PG+KGE G  G P   GP G+PGERG  
Sbjct: 744 GEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGET 803

Query: 428 GERGPRGTPGTRGPRGDP---GEAGPQGDQGREGPVGV---PGDPGEAGPIGPKGYRGDE 481
           G  GP G PG  G  G+P   GE G  G++G  GP GV   PG  G AGP GP+G +G+ 
Sbjct: 804 GPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGER 863

Query: 482 GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTK 540
           G PG  GA G PG  G PG PG  G  G  GP+G+ G +G PG  G  G  G+PG++G K
Sbjct: 864 GSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPK 923

Query: 541 ---GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
              G PG KG  G  G PG       P G+ G  G RG  GP G PG +G PGP
Sbjct: 924 GDAGQPGEKGSPGAQGPPGAP----GPLGIAGITGARGLAGPPGMPGPRGSPGP 973



 Score =  295 bits (754), Expect = 2e-79
 Identities = 178/399 (44%), Positives = 196/399 (49%), Gaps = 68/399 (17%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
           G  G  G PG  GERG PG PG KG AG PG PG  G  G+ G  GEKG  G  G +G  
Sbjct: 228 GKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGEN 287

Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376
           G  GE G  G  G  G  GE G PGLPG  G+ G DG +G  G  G PG  G  G  G P
Sbjct: 288 GLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSP 347

Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGP------------------PGEKGEAGDEGNPGPD 418
           GA GE G  GS G +G  GQ GEPGP                  PG KGE G  G PG  
Sbjct: 348 GAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAP 407

Query: 419 GAPGERGGPGERGPRGTPGTRGPRGDP------GEAGPQGDQGREGPVGVPGDPGEAGPI 472
           G  G RG PG  G  G PG RG  G+P      GE GP+G++G  G  GVPG  GE G  
Sbjct: 408 GLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKD 467

Query: 473 GPKGYRGDEGPPGSEGARGAP---GPAGP---PGDPGLMGERGEDGPAG----------N 516
           G  G  G  G PG+ G RGAP   GPAGP   PG+ G  GERG  GPAG          +
Sbjct: 468 GSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRD 527

Query: 517 GTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGP 576
           G  G PG  G PG+ G PG +G  G PG +G+ G  G PG       PRG  G  G+ GP
Sbjct: 528 GVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPS----GPRGQPGVMGFPGP 583

Query: 577 E------------------GPQGPPGH------QGPPGP 591
           +                  GPQGPPG       QGPPGP
Sbjct: 584 KGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGP 622



 Score =  292 bits (747), Expect = 1e-78
 Identities = 162/345 (46%), Positives = 184/345 (53%), Gaps = 22/345 (6%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
           GP G  G PG  G  G PG PG  G  G PG PG  GP G  G  G  G  G  G  G  
Sbjct: 174 GPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGES 233

Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376
           G  G  G+RG+ G  G+KG  G PG PG KG  GFDG  G    KG+ GA GLKGE G P
Sbjct: 234 GRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGE---KGETGAPGLKGENGLP 290

Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGE---AGDEGNPGPDGAPGERGGP------ 427
           G +G  G  G  G  G+ G+PG PG  G +G     G +G PGP G PG  G P      
Sbjct: 291 GENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAK 350

Query: 428 GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487
           GE GP G+PG+ G  G  GE GPQG  G +GP G PG  G  G  G  G  G  G PG  
Sbjct: 351 GEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLM 410

Query: 488 GARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKG 547
           GARG PGPAG  G PGL G  GE  P  NG +G PG  G  G  G PG+      PG KG
Sbjct: 411 GARGPPGPAGANGAPGLRGGAGE--PGKNGAKGEPGPRGERGEAGIPGV------PGAKG 462

Query: 548 DEGEAGDPGDDNNDIAP--RGVKGAKGYRGPEGPQGPPGHQGPPG 590
           ++G+ G PG+   +  P   G +GA G+RGP GP G PG +GP G
Sbjct: 463 EDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAG 507



 Score =  292 bits (747), Expect = 1e-78
 Identities = 168/374 (44%), Positives = 193/374 (51%), Gaps = 39/374 (10%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
           G  G RG PGF G  G  G+PGEKG AG+ G PG  GP G  G  G  G  G  G RG  
Sbjct: 480 GAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMP 539

Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376
           G  G  G  G  G  G +GE G PG PG  G  G  G+ G PGPKG+ GA G  GE+G P
Sbjct: 540 GSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGP 599

Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD------EGNPGPDGAPGERGGPGER 430
           G  G  G PG +G +G +G PG  GP G+KG+ G       +G PG  G PGE G PGE 
Sbjct: 600 GGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEP 659

Query: 431 GPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGAR 490
           GP+G  G  G  G  G+AG  G++G  G  G PG  G AGP GP+G +G  GPPG  GA 
Sbjct: 660 GPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAA 719

Query: 491 GAPGPAGPPGD------PGLMGERGE------------DGPAG-NGTEGFPGFPGYPGNR 531
           G PG  G PG+      PG  G++GE            DGP G  G  G PG  G PG++
Sbjct: 720 GTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDK 779

Query: 532 ---GAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAP-----------RGVKGAKGYRGPE 577
              GAPG+ G  G  G  G+ GE G PG      AP           RG  G KG  GP 
Sbjct: 780 GEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPP 839

Query: 578 GPQGPPGHQGPPGP 591
           G  GPPG  GP GP
Sbjct: 840 GVAGPPGGSGPAGP 853



 Score =  290 bits (743), Expect = 4e-78
 Identities = 181/412 (43%), Positives = 205/412 (49%), Gaps = 78/412 (18%)

Query: 257 GPPGLRG---DPGFEGERGKPGLPGEKGEAGDPGRPGDLGP------VGYQGMKGEKGSR 307
           G PG+RG    PG  G  GKPG PG +GE+G PG PG  GP      +G+ G KG  G+ 
Sbjct: 531 GGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAP 590

Query: 308 GEKGSRG---------PKGYKGEKGKRGIDGVDGV---KGEMGYPG------LPGCKGSP 349
           G+ G RG         P G  GE G +G  G  G    KG+ G PG      LPG  G P
Sbjct: 591 GKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPP 650

Query: 350 GFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEA 409
           G +G  G PGPKGD GA G  G KG+ GA GE G PG +G  G  G  G PGP G KG A
Sbjct: 651 GENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAA 710

Query: 410 GDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDP------------GEAGPQGDQGRE 457
           G  G PG  G PG +G PGERG  G+PG +G +G+P            G  GP G  G  
Sbjct: 711 GPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPP 770

Query: 458 GPVGVPGD---------PGEAGPIGPKGYRGDEGP---------------PGSEGARGAP 493
           GP G PGD         PG AGP G  G RG+ GP               PG +G RGAP
Sbjct: 771 GPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAP 830

Query: 494 GPAGPPGDPGLMGERGEDGPAG----------NGTEGFPGFPGYPGNR---GAPGINGTK 540
           G  G  G PG+ G  G  GPAG           G+ G PG  G+PG R   G PG NG  
Sbjct: 831 GEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNP 890

Query: 541 GYPGLKGDEGEAGDPGDDNNDIAP--RGVKGAKGYRGPEGPQGPPGHQGPPG 590
           G PG  G  G+ G PG   N  AP   GV G KG  G  G +G PG QGPPG
Sbjct: 891 GPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPG 942



 Score =  289 bits (740), Expect = 8e-78
 Identities = 166/362 (45%), Positives = 188/362 (51%), Gaps = 36/362 (9%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            GPPG+ G PG  G  G PG  G KGE G PG PG  G  G +G+ G  GS G  G  GP 
Sbjct: 837  GPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPS 896

Query: 317  GYKGEKG------KRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP---------- 360
            G  G+ G        G  G  GV G  G  G PG KGSPG  G  G PGP          
Sbjct: 897  GSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGAR 956

Query: 361  --KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD---EGNP 415
               G PG  G +G  G  G  GE+G+PG++G SG+ G PG  G PG  G AG+   +GNP
Sbjct: 957  GLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNP 1016

Query: 416  GPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475
            G DG PG  G PG +G RG  G+ G  G PG  GP G     GP G  GD GE+GP GP 
Sbjct: 1017 GSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGP---VGPAGKSGDRGESGPAGP- 1072

Query: 476  GYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAP 534
                  G PG  G+RGAPGP GP GD G  GERG  G  G+ G  G PG PG PG  G  
Sbjct: 1073 -----AGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQ 1127

Query: 535  GINGTKGYPGLKGDEGEAGDPGDDNND-----IAPRGVKGAKGYRGPEGPQGPPGHQGPP 589
            G  G+ G  G +G  G +G PG D        I P G +G +G RG EG  G PG  GPP
Sbjct: 1128 GAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPP 1187

Query: 590  GP 591
            GP
Sbjct: 1188 GP 1189



 Score =  286 bits (731), Expect = 9e-77
 Identities = 170/373 (45%), Positives = 190/373 (50%), Gaps = 39/373 (10%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
           G PGL+G+ G  GE G PG  G +G  G+ GRPG  G  G +G  G +GS G+ G  GP 
Sbjct: 279 GAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPP 338

Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPG---FDGIQGPP--------------- 358
           G  G  G  G  G  G  G  G  G PG +G PG     G QGPP               
Sbjct: 339 GTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEM 398

Query: 359 GPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQ---PGEPGPPGEKGEAGDEGNP 415
           GP G PGA GL G +G PG  G  G PG  G +G+ G+    GEPGP GE+GEAG  G P
Sbjct: 399 GPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVP 458

Query: 416 GPDGAPGERGGPGERGPRGTPGTRGPRGDP---GEAGPQGDQGREGPVGVPGDPGEAGPI 472
           G  G  G+ G PGE G  G PG  G RG P   G AGP G  G +GP G  G PG AGP 
Sbjct: 459 GAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPR 518

Query: 473 GPKGYRGDEGPPGSEGARGAPG-PAGP-----PGDPGLMGERGEDGPAG----NGTEGFP 522
           G  G  G +G PG  G RG PG P GP     PG PG  GE G  GP G     G  G  
Sbjct: 519 GAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVM 578

Query: 523 GFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN-----NDIAPRGVKGAKGYRGPE 577
           GFPG  GN GAPG NG +G PG  G +G  G  G+           P G KG  G  GP+
Sbjct: 579 GFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQ 638

Query: 578 GPQGPPGHQGPPG 590
           G QG PG  GPPG
Sbjct: 639 GLQGLPGTGGPPG 651



 Score =  283 bits (725), Expect = 4e-76
 Identities = 165/365 (45%), Positives = 188/365 (51%), Gaps = 35/365 (9%)

Query: 257  GPPGLRG---DPGFEGERGKPGLPGEKGEAGDPGRPGD------------LGPVGYQGMK 301
            GPPG  G   +PG +G+ G PG PG KG+AG PG  G              GP G +G K
Sbjct: 648  GPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGK 707

Query: 302  GEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361
            G  G  G  G+ G  G +G  G+RG  G  G KG+ G PG PG  G PG DG +GP GP 
Sbjct: 708  GAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPI 767

Query: 362  GDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAP 421
            G PG  G  G+KGE GA G    PG +GP G  G+ GE GPPG  G  G  G  G  G  
Sbjct: 768  GPPGPAGQPGDKGEGGAPG---LPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGK 824

Query: 422  GERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAG-------PIGP 474
            GERG PGE+G  G PG  GP G  G AGP G QG +G  G PG PG AG       P GP
Sbjct: 825  GERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLP-GP 883

Query: 475  KGYRGDEGPPGSEGARGAPGPAGP------PGDPGLMGERGEDG-PAGNGTEGFPGFPGY 527
             G  G+ GPPG  G+ G  GP GP      PG PG+ G +G+ G P   G+ G  G PG 
Sbjct: 884  PGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGA 943

Query: 528  PGNRGAPGINGTKGYPGLKGDEGEAGDPGDD--NNDIAPRGVKGAKGYRGPEGPQGPPGH 585
            PG  G  GI G +G  G  G  G  G PG      +    G  G  G RGP GPQG PG 
Sbjct: 944  PGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGL 1003

Query: 586  QGPPG 590
             G  G
Sbjct: 1004 AGTAG 1008



 Score =  271 bits (694), Expect = 2e-72
 Identities = 149/333 (44%), Positives = 177/333 (53%), Gaps = 20/333 (6%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            GPPG  G+PG  G  G PG  G  G AG+ G PG     G  G KG+ G  GEKGS G +
Sbjct: 882  GPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGS---PGVSGPKGDAGQPGEKGSPGAQ 938

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376
            G  G  G  GI G+ G +G  G PG+PG +GSPG  G++   G  G PGA GL GE+G P
Sbjct: 939  GPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVK---GESGKPGANGLSGERGPP 995

Query: 377  GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436
            G  G  G  G++G  G +G PG  G PG  G  G +G+ G +G+PG  G PG  GP G  
Sbjct: 996  GPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPV 1055

Query: 437  GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPA 496
            G  G  GD GE+GP G  G  GP G  G PG  GP G KG  G+ G  G +G RG PG  
Sbjct: 1056 GPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNP 1115

Query: 497  GPPGDPGLMGERGEDG-PAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDP 555
            G PG PG  G++G  G P   G  G  G  G PG  G  G  G  G PG +G+ GE    
Sbjct: 1116 GAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGE---- 1171

Query: 556  GDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGP 588
                     RG +G+ G+ G  GP GPPG  GP
Sbjct: 1172 ---------RGSEGSPGHPGQPGPPGPPGAPGP 1195



 Score =  260 bits (665), Expect = 4e-69
 Identities = 138/316 (43%), Positives = 161/316 (50%), Gaps = 14/316 (4%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            G  G  G PG  G +G  G PGEKG  G  G PG  GP+G  G+ G +G  G  G  GP+
Sbjct: 909  GNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPR 968

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376
            G  G +G +G  G  G  G  G  G PG +G PG  G  G PG  G+PG+ GL G  G P
Sbjct: 969  GSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSP 1028

Query: 377  GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436
            G  G+ G  GS G  G  G PG PGP G  G++GD G  GP    G  G PG  G RG P
Sbjct: 1029 GGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGP---AGPAGAPGPAGSRGAP 1085

Query: 437  GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPA 496
            G +GPRGD GE G +G  G +G  G PG+PG  G  GP G +G  G PG  G RG  GP+
Sbjct: 1086 GPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPS 1145

Query: 497  GPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPG 556
            GPPG  G  G  G  GP           PG  GNRG  G  G+ G+PG  G  G  G PG
Sbjct: 1146 GPPGKDGTSGHPGPIGP-----------PGPRGNRGERGSEGSPGHPGQPGPPGPPGAPG 1194

Query: 557  DDNNDIAPRGVKGAKG 572
                 +    + G  G
Sbjct: 1195 PCCGGVGAAAIAGIGG 1210



 Score =  227 bits (579), Expect = 4e-59
 Identities = 130/278 (46%), Positives = 145/278 (52%), Gaps = 13/278 (4%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGR---PGDLGPVGYQGMKGEKGSRGEKGSR 313
            G  GL G PG  G RG PG  G KGE+G PG     G+ GP G QG+ G  G+ GE G  
Sbjct: 954  GARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRD 1013

Query: 314  GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373
            G  G  G  G+ G  G  G +GE G PG PG  G PG  G  GP G  GD G  G  G  
Sbjct: 1014 GNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPA 1073

Query: 374  GEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPR 433
            G PG  G  G PG  GP GD+G+ GE G  G KG  G  GNP   GAPG  G  G++G  
Sbjct: 1074 GAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNP---GAPGSPGPAGQQGAI 1130

Query: 434  GTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAP 493
            G+PG  GPRG  G +GP G        G  G PG  GP GP+G RG+ G  GS G  G P
Sbjct: 1131 GSPGPAGPRGPVGPSGPPGKD------GTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQP 1184

Query: 494  GPAGPPGDPG-LMGERGEDGPAGNGTEGFPGFPGYPGN 530
            GP GPPG PG   G  G    AG G E   GF  Y G+
Sbjct: 1185 GPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYYGD 1222



 Score =  191 bits (486), Expect = 2e-48
 Identities = 115/259 (44%), Positives = 126/259 (48%), Gaps = 38/259 (14%)

Query: 355 QGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPG--EKGEAGDE 412
           QGP GPKGDPG  G+ G  G+PG  G+ G PGS            PGPPG  E    G +
Sbjct: 102 QGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGS------------PGPPGICESCPTGPQ 149

Query: 413 GNP---------------GPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGRE 457
                             G  G PG  G PG  GP GT G  G  G PG  GP G+ G+ 
Sbjct: 150 NYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQA 209

Query: 458 GPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAP------GPAGPPGDPGLMGERGED 511
           GP G PG PG  GP GP G  G+ G PG  G RG P      GPAG PG PG+ G RG D
Sbjct: 210 GPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFD 269

Query: 512 GPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAK 571
           G   NG +G  G PG  G  G PG NG  G  G +G  GE G PG        RG  GA+
Sbjct: 270 G--RNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLP-GAAGARGNDGAR 326

Query: 572 GYRGPEGPQGPPGHQGPPG 590
           G  G  GP GPPG  G PG
Sbjct: 327 GSDGQPGPPGPPGTAGFPG 345



 Score =  176 bits (445), Expect = 1e-43
 Identities = 105/240 (43%), Positives = 119/240 (49%), Gaps = 22/240 (9%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            RGPPG +G PG  G  G+PG  G  G  G PGR G  G  G +G  G  G+ G  G  GP
Sbjct: 992  RGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGP 1051

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE--- 372
             G  G  GK G  G  G  G  G PG  G +G+PG      P GP+GD G  G +G    
Sbjct: 1052 PGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPG------PQGPRGDKGETGERGAAGI 1105

Query: 373  KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA---PGERGGPGE 429
            KG  G  G  G PGS GP+G +G  G PGP G +G  G  G PG DG    PG  G PG 
Sbjct: 1106 KGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGP 1165

Query: 430  RGPRGTPGTRGPRGDPGEAGPQGDQGREGP-------VGVPGDPGE-AGPIGPKGYRGDE 481
            RG RG  G+ G  G PG+ GP G  G  GP         + G  GE AG   P  Y GDE
Sbjct: 1166 RGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAP--YYGDE 1223



 Score =  132 bits (333), Expect = 1e-30
 Identities = 92/263 (34%), Positives = 107/263 (40%), Gaps = 68/263 (25%)

Query: 397 PGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGR 456
           P    P GE      +    P   P  +G  G +G  G PG  G  GDPG  G  G  G 
Sbjct: 75  PNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGS 134

Query: 457 EGPVGV--------------------------------PGDPGEAGPIGPKGYRGDEGPP 484
            GP G+                                PG  G  GP GP G  G  G P
Sbjct: 135 PGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSP 194

Query: 485 GSEGARGAP------GPAGPPGDPGLM------------------GERGEDGPAG-NGTE 519
           GS G +G P      GP+GPPG PG +                  GERG  GP G  G  
Sbjct: 195 GSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPA 254

Query: 520 GFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN--NDIAPR---------GVK 568
           G PGFPG  G+RG  G NG KG  G  G +GE G PG++     + PR         G+ 
Sbjct: 255 GIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLP 314

Query: 569 GAKGYRGPEGPQGPPGHQGPPGP 591
           GA G RG +G +G  G  GPPGP
Sbjct: 315 GAAGARGNDGARGSDGQPGPPGP 337



 Score =  105 bits (263), Expect = 2e-22
 Identities = 64/142 (45%), Positives = 71/142 (50%), Gaps = 4/142 (2%)

Query: 255  ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314
            A GP G RGD G  GERG  G+ G +G  G+PG PG  GP G QG  G  G  G +G  G
Sbjct: 1084 APGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVG 1143

Query: 315  PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPG-AFGLKGEK 373
            P G  G+ G  G  G  G  G  G  G  G +GSPG  G  GPPGP G PG   G  G  
Sbjct: 1144 PSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAA 1203

Query: 374  GEPGADGEAGRPGSSGP-SGDE 394
               G  GE  + G   P  GDE
Sbjct: 1204 AIAGIGGE--KAGGFAPYYGDE 1223



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 40/110 (36%), Positives = 46/110 (41%), Gaps = 25/110 (22%)

Query: 253  QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312
            Q A G PG  G  G  G  G PG  G        G PG +GP       G +G+RGE+GS
Sbjct: 1127 QGAIGSPGPAGPRGPVGPSGPPGKDGTS------GHPGPIGP------PGPRGNRGERGS 1174

Query: 313  RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPG-CKGSPGFDGIQGPPGPK 361
             G  G+ G+             G  G PG PG C G  G   I G  G K
Sbjct: 1175 EGSPGHPGQ------------PGPPGPPGAPGPCCGGVGAAAIAGIGGEK 1212


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  311 bits (797), Expect = 2e-84
 Identities = 178/378 (47%), Positives = 202/378 (53%), Gaps = 44/378 (11%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGM------KGEKGSRGEK 310
            G PG  G  G  G RG+ GL G+KG+ G  G PG  GPVG QG+      KGE G  G+ 
Sbjct: 1189 GQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQM 1248

Query: 311  GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370
            G  GP G +G  G  G DG  G  G +G PG  G KG PG  G  G PG  G PG  G +
Sbjct: 1249 GPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGER 1308

Query: 371  GEKGEPGADGEAGRPGSSGPSGDEGQ---------PGEPGPPGEKGEAGDEGNP---GPD 418
            GEKGE G  G AG PG  GP GD+G          PG+PGPPGE G AG +G P   G D
Sbjct: 1309 GEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDD 1368

Query: 419  GAPGERGGP---GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475
            G PG+ G P   GE GP G PG RGP G  G  G QG++G +G  G+ G PG+ GPIGP+
Sbjct: 1369 GEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQ 1428

Query: 476  GYRGDEGP---------------PGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN---- 516
            G  G  GP               PGS G  G PGP GPPG PGL G+ G  G  G+    
Sbjct: 1429 GAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLI 1488

Query: 517  GTEGFPGFPGYPGNRGAP---GINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573
            G  G PG  G  G+RG P   G +G KG  G+ G  G  G PG       P G KGAKG 
Sbjct: 1489 GLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLP-GPPGPKGAKGS 1547

Query: 574  RGPEGPQGPPGHQGPPGP 591
             GP GP+G  GH GPPGP
Sbjct: 1548 SGPTGPKGEAGHPGPPGP 1565



 Score =  305 bits (781), Expect = 1e-82
 Identities = 167/346 (48%), Positives = 190/346 (54%), Gaps = 15/346 (4%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            G PGL G PG +G  G PG  G  GE G  G PG  GP+GY G +G KG+ G +G +G K
Sbjct: 748  GKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTK 807

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376
            G KGE G  G  G  G+KG+ G  G PG +G  G +G +G  GP GDPG  G  GEKG+ 
Sbjct: 808  GEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKL 867

Query: 377  GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436
            G  G  G PG  GP G  G PG PG  GEKG  G  G PGP G  G  G  GERGPRG  
Sbjct: 868  GVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGIT 927

Query: 437  GTRGPRGD---PGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAP 493
            G  GP+G+    G AGP G++G  GP G  G PG  GP GP G  G  G PG  G  G  
Sbjct: 928  GKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 987

Query: 494  GPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEA 552
            G  GPPG PG++G +G  G  G  G  G PG PG PG +G PG+ G +   G KGD G A
Sbjct: 988  GKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKE---GTKGDPGPA 1044

Query: 553  GDPGDDN--------NDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
            G PG D          D    G  GA G +G EGP GPPG  G PG
Sbjct: 1045 GLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPG 1090



 Score =  298 bits (764), Expect = 1e-80
 Identities = 170/382 (44%), Positives = 201/382 (52%), Gaps = 45/382 (11%)

Query: 253  QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP---VGYQGMKGEKGSRGE 309
            Q   G PG +G PG  G+ G PG PG++GE G  G+ G  GP   VG QG  GE G  GE
Sbjct: 954  QGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGE 1013

Query: 310  KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGL 369
            +G  GP G  GE+G  G+ G +G KG+ G  GLPG  G PG  G  G  G  G  GA GL
Sbjct: 1014 RGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGL 1073

Query: 370  KGEKGEPGADGEAGRPGSSGPSGDEGQ---PGEPGPPGEKGEAGDEGNPGPDGAPGERGG 426
            KG +G PG  G AG PG  GP+G  G    PG PGP G  G AG++G PG  G  G  G 
Sbjct: 1074 KGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR 1133

Query: 427  PGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGS 486
             G +GP G PG  GP G PGE G +G+ G  G  G  GD GE GP GP G +G  G PG 
Sbjct: 1134 DGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGP 1193

Query: 487  EGARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFPGYPGNR----------- 531
             GA G PGP G     GL G++G++GP G     G  G  G PG PG +           
Sbjct: 1194 SGADGEPGPRG---QQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGP 1250

Query: 532  ----------GAPGINGTKGYP---------GLKGDEGEAGDPG--DDNNDIAPRGVKGA 570
                      GAPG +G +G P         G KG+ GEAG+PG   +     P+G +G 
Sbjct: 1251 PGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGE 1310

Query: 571  KGYRGPEGPQGPPGHQGPPGPD 592
            KG  GP G  GPPG +GPPG D
Sbjct: 1311 KGESGPSGAAGPPGPKGPPGDD 1332



 Score =  292 bits (748), Expect = 1e-78
 Identities = 160/347 (46%), Positives = 185/347 (53%), Gaps = 20/347 (5%)

Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314
           ARG PG  G  G  G  G  GLPGEKG  GDPG  G  GP       G+ G RG+ G  G
Sbjct: 617 ARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGP------PGDDGERGDDGEVG 670

Query: 315 PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKG 374
           P+G  GE G RG+ G  G  G  G PG+ G  G PG  G  GP G  G PG  G  G +G
Sbjct: 671 PRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQG 730

Query: 375 EPGADGEAGRPGSSGPSGDEGQP------GEPGPPGEKGEAGDEGNPGPDGAPGERGGPG 428
            PG  G  G PG  GP G  G P      G PG PG++G  G++G  GP G  G  G PG
Sbjct: 731 LPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPG 790

Query: 429 ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEG 488
            RG +G  G RG +G  GE G  G  G +G +G+ GD GE GP GP+G  G EGP G  G
Sbjct: 791 PRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGG 850

Query: 489 ARGAPGPAGPPGDPGLMGERGEDG-PAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKG 547
             G PGP GPPG+ G +G  G  G P   G +G  GFPG+PG  G  G  GT G PG +G
Sbjct: 851 PNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRG 910

Query: 548 DEGEAGDPGDDNNDIAPRGV---KGAKGYRGPEGPQGPPGHQGPPGP 591
             G  G  G+      PRG+    G KG  G +GP GPPG +GP GP
Sbjct: 911 QRGPTGPRGER----GPRGITGKPGPKGNSGGDGPAGPPGERGPNGP 953



 Score =  292 bits (748), Expect = 1e-78
 Identities = 163/356 (45%), Positives = 182/356 (51%), Gaps = 25/356 (7%)

Query: 256  RGPPGLRGDPGFEGERGKPG------------LPGEKGEAGDPGRPGDLGPVGYQGMKGE 303
            +GPPG  G+ G  GE+G  G            LPG  G  G PG  GD G +G  G KG 
Sbjct: 1110 QGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGS 1169

Query: 304  KGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD 363
            KG +GE+G  GP G +G  G+ G  G DG  G  G  GL G KG  G  G  GPPGP G 
Sbjct: 1170 KGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGL 1229

Query: 364  PGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGE 423
             G  G  GEKGE G  G+ G PG  GP G  G PG  GP G  G  G+ G  G  G PGE
Sbjct: 1230 QGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGE 1289

Query: 424  RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGP 483
             G PG  G  G PG +G RG+ GE+GP G  G  GP G PGD G  G  GP G+ GD GP
Sbjct: 1290 AGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGP 1349

Query: 484  PGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYP 543
            PG  G  G  GP G  GD G  G+ G  GP G      PG  G PG RG PG  G +G  
Sbjct: 1350 PGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGE-----PGPSGPPGKRGPPGPAGPEGRQ 1404

Query: 544  GLKGDEGEAG--DPGDDNNDIAPRGV------KGAKGYRGPEGPQGPPGHQGPPGP 591
            G KG +GEAG   P      I P+G        G +G  GP G QG PG  GP GP
Sbjct: 1405 GEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGP 1460



 Score =  290 bits (741), Expect = 6e-78
 Identities = 169/380 (44%), Positives = 189/380 (49%), Gaps = 48/380 (12%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            GPPGLRG PG  G  G  G  G KG  G PG PG  G  G +G  G  G  G  G  GP+
Sbjct: 1051 GPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQ 1110

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376
            G  G  G++G  G  G +G  G  GL G  G PG  G  GPPG  GD G  G  G+KG  
Sbjct: 1111 GPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSK 1170

Query: 377  GADGEAGRPGSSGPSGDEGQPG------EPGPPGEKG---EAGDEGN------------- 414
            G  GE G PG +GP G  GQPG      EPGP G++G   + GDEG              
Sbjct: 1171 GDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQ 1230

Query: 415  --PGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQ------------GDQGREGPV 460
              PGP G  GE G  G+ GP G PG RGP G PG  GPQ            G++G  G  
Sbjct: 1231 GLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEA 1290

Query: 461  GVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTE 519
            G PG PGE GP GPKG RG++G  G  GA G PGP GPPGD    G +G  GP G  G  
Sbjct: 1291 GEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDD---GPKGSPGPVGFPGDP 1347

Query: 520  GFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN--------NDIAPRGVKGAK 571
            G PG PG  G  G PG  G  G PG  G  G  G+PG               P G +G K
Sbjct: 1348 GPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEK 1407

Query: 572  GYRGPEGPQGPPGHQGPPGP 591
            G +G  G +GPPG  GP GP
Sbjct: 1408 GAKGEAGLEGPPGKTGPIGP 1427



 Score =  288 bits (738), Expect = 1e-77
 Identities = 168/368 (45%), Positives = 198/368 (53%), Gaps = 39/368 (10%)

Query: 257  GPPGLRGDPGFEGERGKPGL---------PGEKGEAGDPGRPG---------DLGPVGYQ 298
            GPPG RG+ G EG +G+ G          PGEKG+ G PG PG          +G  G+ 
Sbjct: 832  GPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFP 891

Query: 299  GMKGEKGSRGE------KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFD 352
            G  GEKG RG       +G RGP G +GE+G RGI G  G KG  G  G  G  G  G +
Sbjct: 892  GANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPN 951

Query: 353  GIQGP---PGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEA 409
            G QGP   PGPKG PG  G  G  G PG  GE G  G +GP G  G  G  GP GE G  
Sbjct: 952  GPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPM 1011

Query: 410  GDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEA 469
            G+ G+PGP G PGE+G PG  G  GT G  GP G PG+ GP G +      G PGD G  
Sbjct: 1012 GERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLR------GFPGDRGLP 1065

Query: 470  GPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYP 528
            GP+G  G +G+EGPPG  G  G+PG  GP G  G +G  G  GP G  G  G  G PG  
Sbjct: 1066 GPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEK 1125

Query: 529  GNRGAPGINGTKGYPGLKGDEGEAGDPGDDNN--DIAPRGVKGAKGYRGPEGPQGPPGHQ 586
            G +G  G +G +G  GL G  G  G PG+D +  +I   G KG+KG +G +GP GP G Q
Sbjct: 1126 GPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQ 1185

Query: 587  GP---PGP 591
            GP   PGP
Sbjct: 1186 GPIGQPGP 1193



 Score =  286 bits (731), Expect = 9e-77
 Identities = 169/365 (46%), Positives = 193/365 (52%), Gaps = 35/365 (9%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS---R 313
            GPPG  G  G  GERG  G  G  G  G PG  G  GP G +G  GEKG +G  G    +
Sbjct: 1078 GPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQ 1137

Query: 314  GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKG---DPGAFGLK 370
            GP G  G  G  G  G DG KGE+G PG  G KG  G  G  GP GP+G    PG  G  
Sbjct: 1138 GPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGAD 1197

Query: 371  GEKGEPGADGEAGRPGSSGPSGDEGQPGE------PGPPGEKGEAGDEGNPGPDGAPGER 424
            GE G  G  G  G+ G  GP G  G PG       PGPPGEKGE GD G  GP G PG R
Sbjct: 1198 GEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPR 1257

Query: 425  G---GPGERGPR------GTPGTRGPRGDPGEAGP---QGDQGREGPVGVPGDPGEAGPI 472
            G    PG  GP+      G PG  G +G+PGEAG     G+ G  GP G  G+ GE+GP 
Sbjct: 1258 GPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPS 1317

Query: 473  GPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGE---RGEDGPAGN-GTEGFPGFPGYP 528
            G  G  G +GPPG +G +G+PGP G PGDPG  GE    G+DGP G+ G +G PG  G P
Sbjct: 1318 GAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSP 1377

Query: 529  GNRGAPGIN---GTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGH 585
            G  G PG +   G +G PG  G EG  G+ G         G++G  G  GP GPQG PG 
Sbjct: 1378 GPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGE----AGLEGPPGKTGPIGPQGAPGK 1433

Query: 586  QGPPG 590
             GP G
Sbjct: 1434 PGPDG 1438



 Score =  282 bits (722), Expect = 1e-75
 Identities = 163/360 (45%), Positives = 191/360 (53%), Gaps = 26/360 (7%)

Query: 257  GPPGLRGDPGFEGERGKPGLPG------EKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310
            G PGL G PG +G +G  G PG      EKG  G PG+PG  G  G  G +GE+G RG  
Sbjct: 868  GVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGIT 927

Query: 311  GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPG---FDGIQGPPGPKGDPGAF 367
            G  GPKG  G  G  G  G  G  G  G  G PG KG PG    DG+ G PG +G+ G  
Sbjct: 928  GKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 987

Query: 368  GLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKG------EAGDEGNPGPDGAP 421
            G  G  G PG  G  G  G +GP G+ G PG PGPPGE+G      + G +G+PGP G P
Sbjct: 988  GKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLP 1047

Query: 422  GERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGD---PGEAGPIGPKGYR 478
            G+ G PG RG  G  G  GP G  G  G +G  G  GP G PG+    G AGPIG  G  
Sbjct: 1048 GKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRP 1107

Query: 479  GDEGPPGSEGARGAP---GPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFPGYPGNR 531
            G +GPPG  G +GAP   GP GP G  GL G  G  GPAG     G +G  G  G PG +
Sbjct: 1108 GPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQK 1167

Query: 532  GAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
            G+ G  G +G PG  G +G  G PG    D  P G +G +G  G +G +GP G  GPPGP
Sbjct: 1168 GSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEP-GPRGQQGLFGQKGDEGPRGFPGPPGP 1226



 Score =  281 bits (719), Expect = 2e-75
 Identities = 170/400 (42%), Positives = 199/400 (49%), Gaps = 71/400 (17%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            RG  GL G PG +G RG PG  G  G  GD G  GD G VG +G+ GE G RG  G +GP
Sbjct: 630  RGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGP 689

Query: 316  KGYKGEKGKRGIDGVDGVKGEMG---YPGLPGCKGSPGFDGIQGPPG---PKGDPGAFGL 369
             G  G  G  G+DG  G KG +G    PG PG +G+PG  G+ GP G   P G+ G  G 
Sbjct: 690  PGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGK 749

Query: 370  KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGE---------------------KGE 408
             G  G PGADG  G PG  GP G++G  G PGP G                      KGE
Sbjct: 750  PGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGE 809

Query: 409  AGDEGNPGPDGAPGERG--------GP-GERGPRGTPGTRGPRGDPGEAGPQGDQGREGP 459
             G++G PG  G  G +G        GP GE GP G  G  GP GDPG  GP G++G+ G 
Sbjct: 810  KGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGV 869

Query: 460  VGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGE--------- 510
             G+PG PG  GP G  G+ G  G  G +G RG PG  GP G  G  G RGE         
Sbjct: 870  PGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGK 929

Query: 511  ---------DGPAG-------NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGD---EGE 551
                     DGPAG       NG +G  GFPG  G  G PG +G  G+PG +G+   +G+
Sbjct: 930  PGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGK 989

Query: 552  AGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
             G PG       P GV G +G  G  GP G  GH GPPGP
Sbjct: 990  TGPPG-------PPGVVGPQGPTGETGPMGERGHPGPPGP 1022



 Score =  276 bits (705), Expect = 9e-74
 Identities = 170/404 (42%), Positives = 197/404 (48%), Gaps = 65/404 (16%)

Query: 253 QPARGPPGL--RGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEK------ 304
           +PA   PG+   G PG EG  G PG PG  G  G  G PG+ GP G  G+ G        
Sbjct: 457 EPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPP 516

Query: 305 ----------GSRGEKGSRGPKGYKGE--------------KGKRGIDGVDGVKGEMGYP 340
                     G  G+ GS+GP     E              +G  G  G+ G  G +G P
Sbjct: 517 GTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPP 576

Query: 341 GLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEP 400
           G  G KG PG  G QGP G +G PG  G  G +G  G+DG  G PG +GP GD G  G  
Sbjct: 577 GSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLA 636

Query: 401 GPPGEKGEAGD---EGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGRE 457
           G PGEKG  GD    G PGP G  GERG  GE GPRG PG  GPRG  G  GP G  G  
Sbjct: 637 GLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPP 696

Query: 458 GPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGP---AGPPGD------PGLMGER 508
           G  G+ G PG  G +GP+G  G  G  G+ GA+G PGP    GPPG+      PGL G  
Sbjct: 697 GVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMP 756

Query: 509 GEDGPAGN-GTEGFPGFP------------GYPGNRGAPGINGTKGYPGLKGDEGEAGDP 555
           G DGP G+ G EG PG              GYPG RG  G +G +G  G KG++GE G P
Sbjct: 757 GADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFP 816

Query: 556 G--------DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
           G         D  +I P G +G  G  GP+G  GP G  GP GP
Sbjct: 817 GFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGP 860



 Score =  275 bits (702), Expect = 2e-73
 Identities = 155/337 (45%), Positives = 183/337 (54%), Gaps = 29/337 (8%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            +GPPG  G+PG  GE+G+PG      EAG+PG PG+ GP G +G +GEKG  G  G+ GP
Sbjct: 1269 QGPPGGIGNPGAVGEKGEPG------EAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGP 1322

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375
             G KG  G    DG  G  G +G+PG PG  G PG  G  GPPG KGD       GE G+
Sbjct: 1323 PGPKGPPGD---DGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGD------DGEPGQ 1373

Query: 376  PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGT 435
             G+ G  G PG SGP G  G PG  GP G +GE G +G  G +G PG+    G  GP+G 
Sbjct: 1374 TGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGK---TGPIGPQGA 1430

Query: 436  PGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGP 495
            PG  GP G  G  GP G+QG  G  G  G PG  GP G  G +GD GP G +G  G  G 
Sbjct: 1431 PGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGL 1490

Query: 496  AGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGD 554
             GPPG+ G  G+RG  GP G +G +G  G  G  G  G PG  G  G PG KG +G +G 
Sbjct: 1491 IGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSG- 1549

Query: 555  PGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
                     P G KG  G+ GP GP GPPG    P P
Sbjct: 1550 ---------PTGPKGEAGHPGPPGPPGPPGEVIQPLP 1577



 Score =  268 bits (686), Expect = 1e-71
 Identities = 164/379 (43%), Positives = 190/379 (50%), Gaps = 53/379 (13%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQG----MKGEKGSRGEKGS 312
           GP GL G PG  G  G+ G PGE+G  G PG PG  G  G  G    +    G  G+ GS
Sbjct: 475 GPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGS 534

Query: 313 RGPKGYKGE--------------KGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPP 358
           +GP     E              +G  G  G+ G  G +G PG  G KG PG  G QGP 
Sbjct: 535 KGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPR 594

Query: 359 GPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPD 418
           G +G PG  G  G +G  G+DG  G PG +GP GD G  G  G PGEKG  GD G  GP 
Sbjct: 595 GVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPP 654

Query: 419 GAPG---ERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475
           G PG   ERG  GE GPRG PG  GPRG  G  GP G  G  G  G+ G PG  G +GP+
Sbjct: 655 GPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQ 714

Query: 476 GYRGDEGPPGSEGARGAPGPAG---PPGD------PGLMGERGEDGPAGN-GTEGFPGFP 525
           G  G  G  G+ GA+G PGP G   PPG+      PGL G  G DGP G+ G EG PG  
Sbjct: 715 GEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEK 774

Query: 526 G------------YPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573
           G            YPG RG  G +G +G  G KG++GE G PG           KG  G 
Sbjct: 775 GGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPG----------FKGDMGI 824

Query: 574 RGPEGPQGPPGHQGPPGPD 592
           +G  G  GPPG +G  GP+
Sbjct: 825 KGDRGEIGPPGPRGEDGPE 843



 Score =  246 bits (628), Expect = 8e-65
 Identities = 149/362 (41%), Positives = 177/362 (48%), Gaps = 36/362 (9%)

Query: 260 GLRGDPGFEGERGKP----------GLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGE 309
           G+ G  G +G++G+P          G PG +G AG PG PG +GP G  G  GE+G  G 
Sbjct: 444 GIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGR 503

Query: 310 KGSRGPKGYKGEKG-------KRGIDGVDGVKGEMG-----------YPGLPGCKGSPGF 351
            G  G  G  G  G       + G  G  G KG M                   +G  G 
Sbjct: 504 PGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGP 563

Query: 352 DGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD 411
            G+ G PGP G PG+ GLKGE G+ G  G  G  G  GP+G  G+ G  G  G +G  G 
Sbjct: 564 MGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQ 623

Query: 412 EGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGP 471
            G  G  G  G  G PGE+G RG PG  GP G PG+ G +GD G  GP G+PG+PG  G 
Sbjct: 624 TGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGL 683

Query: 472 IGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGN 530
           +GPKG  G  GPPG  G  G PGP G       +G +GE GP G  G  G  G PG  G 
Sbjct: 684 LGPKGPPGPPGPPGVTGMDGQPGPKGN------VGPQGEPGPPGQQGNPGAQGLPGPQGA 737

Query: 531 RGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
            G PG  G  G PGL G  G  G PG    +  P G KG +G  GP+GP G PG +G  G
Sbjct: 738 IGPPGEKGPLGKPGLPGMPGADGPPGHPGKE-GPPGEKGGQGPPGPQGPIGYPGPRGVKG 796

Query: 591 PD 592
            D
Sbjct: 797 AD 798



 Score =  121 bits (303), Expect = 4e-27
 Identities = 115/384 (29%), Positives = 142/384 (36%), Gaps = 127/384 (33%)

Query: 320 GEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGAD 379
           G++   GI   D V  E  Y   P    + G +G + P  P  DPGA          GA+
Sbjct: 328 GKEEDVGIGDYDYVPSEDYYTPSPYDDLTYG-EGEENPDQPT-DPGA----------GAE 375

Query: 380 GEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEG---------NP--GPDGAPGERGGPG 428
                  +S  S     PGE G    +GE  +E          +P   P  +P E G PG
Sbjct: 376 IPTSTADTSNSSNPAPPPGE-GADDLEGEFTEETIRNLDENYYDPYYDPTSSPSEIG-PG 433

Query: 429 ERGPRGT--PGTRGPRGDPGEAGP----------QGDQGREGPVGVPGDPGEAGPIGPKG 476
               + T   G  GPRG+ G+ G           +G  G EGP G+PG PG  GP G  G
Sbjct: 434 MPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVG 493

Query: 477 YRGDEGPPGSEGARGAPGPAGPP------------------------------------- 499
             G+ GPPG  G  GA G  GPP                                     
Sbjct: 494 DPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQA 553

Query: 500 -----GDPGLMGERGEDGPAG-------------------NGTEGFPGFPGYPGNRGAPG 535
                G  G MG  G  GP G                    G +G PG  G PG RG  G
Sbjct: 554 RLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAG 613

Query: 536 INGTKGYP---------------GLKGDEGEAGDPG--------------DDNNDIAPRG 566
            +G +G P               GL G++G  GDPG               D+ ++ PRG
Sbjct: 614 SDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRG 673

Query: 567 VKGAKGYRGPEGPQGPPGHQGPPG 590
           + G  G RG  GP+GPPG  GPPG
Sbjct: 674 LPGEPGPRGLLGPKGPPGPPGPPG 697



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 29/69 (42%), Positives = 31/69 (44%), Gaps = 6/69 (8%)

Query: 253  QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312
            Q + GP G +G  G  G  G PG PG       PG PG  G  G  G  G KG  G  G 
Sbjct: 1509 QGSSGPKGEQGITGPSGPIGPPGPPGL------PGPPGPKGAKGSSGPTGPKGEAGHPGP 1562

Query: 313  RGPKGYKGE 321
             GP G  GE
Sbjct: 1563 PGPPGPPGE 1571


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score =  309 bits (792), Expect = 8e-84
 Identities = 182/369 (49%), Positives = 206/369 (55%), Gaps = 41/369 (11%)

Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
           RGP GL G  G  G+ G+PG PG  G  G  GRPGD GP   QG  G  G+ GE G  GP
Sbjct: 533 RGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGP---QGKVGPSGAPGEDGRPGP 589

Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375
            G +G +G+ G+ G  G KG  G PG  G KG PG  G++G PG  G+ GA G  G  G 
Sbjct: 590 PGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGP 649

Query: 376 PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPG------ERGGPGE 429
            G  GE G PG   PSG +G PG PGPPGE G+ GD+G PG  GAPG      ERG PGE
Sbjct: 650 AGERGEQGAPG---PSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE 706

Query: 430 RG---------PRG---TPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY 477
           RG         PRG   TPGT GP+G  G AGP G QG  G  G+PG+ G AG  GPKG 
Sbjct: 707 RGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGD 766

Query: 478 RGD------EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGN 530
           RGD      EG PG +G RG  GP GPPG  G  GE+GE GP G  G+ G  G PG  G 
Sbjct: 767 RGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGE 826

Query: 531 RGAP------GINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGP---EGPQG 581
            G P      G  G  G PG KG++GEAG  GD      P+G  GA G +GP    GP+G
Sbjct: 827 TGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAP-GPQGPSGAPGPQGPTGVTGPKG 885

Query: 582 PPGHQGPPG 590
             G QGPPG
Sbjct: 886 ARGAQGPPG 894



 Score =  300 bits (767), Expect = 6e-81
 Identities = 169/347 (48%), Positives = 191/347 (55%), Gaps = 27/347 (7%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGE------KGEAGDPGRPGDLGPVGYQGMKGEKGSRGE 309
            RG PG RG PG +G +G  GLPG       KG +G  G PG  GP G QGM GE+G+ G 
Sbjct: 701  RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 760

Query: 310  KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGL 369
             G +G +G  GEKG  G  G DG +G  G  G PG  G+ G  G  GPPGP G  GA G 
Sbjct: 761  AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA 820

Query: 370  KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGE 429
             GE+GE G  G AG  G  G  G  G  GE G  G+KG+AG  G  GP GAPG +G  G 
Sbjct: 821  PGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGV 880

Query: 430  RGPRGTPGTRGP---RGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGS 486
             GP+G  G +GP    G PG AG  G  G  G  G PG PG +G  GPKG RGD GPPG 
Sbjct: 881  TGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGR 940

Query: 487  EGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNR---GAPGINGTKGYP 543
             G  G  GPAGPPG+    GE G+DGP  +G EG PG  G  G R   G PG  G +G+P
Sbjct: 941  AGEPGLQGPAGPPGE---KGEPGDDGP--SGAEGPPGPQGLAGQRGIVGLPGQRGERGFP 995

Query: 544  GLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
            GL G  GE G           +G  GA G RGP GP GPPG  GP G
Sbjct: 996  GLPGPSGEPG----------KQGAPGASGDRGPPGPVGPPGLTGPAG 1032



 Score =  298 bits (763), Expect = 2e-80
 Identities = 163/345 (47%), Positives = 187/345 (54%), Gaps = 14/345 (4%)

Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
           RGPPG  G PG +G +G PG PGE G +G  G  G  GP G  G  GE G  G+ G RGP
Sbjct: 209 RGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGP 268

Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375
            G +G +G  G  G+ GVKG  GYPGL G KG  G  G++G  G  G+ G+ G  G +G 
Sbjct: 269 PGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGL 328

Query: 376 PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGT 435
           PG  G  G  G++G  G++GQPG  GPPG  G AG  G PG  GA GE G  G RGP G 
Sbjct: 329 PGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGA 388

Query: 436 PGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGP---IGPKGYRGDEGPPGSEGARGA 492
            G RG  G PG  GP G  G  G  G+PG  G AG     G  G+ G  GPPG +GA G 
Sbjct: 389 QGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGP 448

Query: 493 PGPAGPPGDPGLMGERGEDGPAGN----GTEGFPGFPGYPGNRGA---PGINGTKGYPGL 545
            GP G  G+PG+ G +GE GP G     G +G PG  G  G RGA   PG  G  G PG 
Sbjct: 449 LGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGE 508

Query: 546 KGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           +G  G  G PG D       G KGA G RGP G  GP G  G PG
Sbjct: 509 RGAPGNRGFPGQD----GLAGPKGAPGERGPSGLAGPKGANGDPG 549



 Score =  292 bits (747), Expect = 1e-78
 Identities = 165/360 (45%), Positives = 195/360 (54%), Gaps = 36/360 (10%)

Query: 255 ARGPPGLRGDPGFEGERGKPGL---PGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG 311
           A G PG  G PG +G  G PG+   PG  G  G PG  G  GP+G +G  GE G  G KG
Sbjct: 406 ASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKG 465

Query: 312 SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKG 371
            +GPKG  G  G +G  G  G +G+ G  G PG  G  G  G +G PG +G PG  GL G
Sbjct: 466 EQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAG 525

Query: 372 EKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKG------EAGDEGNPGPDGAPGERG 425
            KG PG  G +G  G  G +GD G+PGEPG PG +G      +AG +G  GP GAPGE G
Sbjct: 526 PKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDG 585

Query: 426 GPGERGPRGT---------PGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAG------ 470
            PG  GP+G          PG +G  G+PG+AG +G  G  G  G+PG  GE G      
Sbjct: 586 RPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG 645

Query: 471 PIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGN 530
           P GP G RG++G PG  G +G PGP GPPG+ G  G++G  G A     G PG  G  G 
Sbjct: 646 PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA-----GAPGLVGPRGE 700

Query: 531 RGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           RG PG  G+ G  GL+G  G  G PG D       G KGA G  GP G QGPPG QG PG
Sbjct: 701 RGFPGERGSPGAQGLQGPRGLPGTPGTD-------GPKGASGPAGPPGAQGPPGLQGMPG 753



 Score =  291 bits (746), Expect = 2e-78
 Identities = 186/476 (39%), Positives = 215/476 (45%), Gaps = 138/476 (28%)

Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDP------------GRPGDLGP------ 294
           Q ARG PG  G PG +G RG PGL G KGEAG P            G PG +GP      
Sbjct: 272 QGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGE 331

Query: 295 ---------------------------------VGYQGMKGEKGSRGEKGSRGPKGYKGE 321
                                             G+ G  G KG  G  G+RGP+G +G 
Sbjct: 332 RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGP 391

Query: 322 KGKRGI------------DGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK-------- 361
           +G+ G              G DG+ G  G  G PG  G+PGF G +GPPGP+        
Sbjct: 392 RGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGP 451

Query: 362 ----GDPGAFGLKGE---KGEPGADGEAGRPGSSGPSGDEGQPGEP------GPPGEKGE 408
               G+PG  G KGE   KGEPG  G  G PG +G  G  G  GEP      GPPGE+G 
Sbjct: 452 KGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGA 511

Query: 409 AGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGE 468
            G+ G PG DG  G +G PGERGP G  G +G  GDPG  G  G  G  G  G PGD G 
Sbjct: 512 PGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGP 571

Query: 469 AGPIGPKGYRGDE---GPPGSEGARGAP-------------------------------- 493
            G +GP G  G++   GPPG +GARG P                                
Sbjct: 572 QGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGL 631

Query: 494 -------GPAGPPGDPGLMGERGEDG-PAGNGTEGFPGFPGYPGNRGAP---GINGTKGY 542
                  G AGPPG  G  GERGE G P  +G +G PG PG PG  G P   G+ G  G 
Sbjct: 632 PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA 691

Query: 543 PGLKGDEGEAGDPGDDNNDIA-----PRGVKGAKGYRGPE---GPQGPPGHQGPPG 590
           PGL G  GE G PG+  +  A     PRG+ G  G  GP+   GP GPPG QGPPG
Sbjct: 692 PGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPG 747



 Score =  291 bits (746), Expect = 2e-78
 Identities = 167/382 (43%), Positives = 196/382 (51%), Gaps = 44/382 (11%)

Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPG------RPGDLGPVGYQGMKGEKGS 306
           Q ARG PG+ G PG +G  G+PG  GEKG  G PG      + G+ G  G  G  G  G 
Sbjct: 593 QGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGE 652

Query: 307 RGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366
           RGE+G+ GP G++G  G  G  G  G  G+ G PG  G  G  G  G +G PG +G PGA
Sbjct: 653 RGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGA 712

Query: 367 FGLKGEKGEPG---------ADGEAGRPGSSGPSGDEGQPGEPGPPG---EKGEAGDEGN 414
            GL+G +G PG         A G AG PG+ GP G +G PGE G  G    KG+ GD G 
Sbjct: 713 QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGE 772

Query: 415 PGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGP 474
            GP+GAPG+ GG G  GP G PG  G  G+ GE GP G  G  G  G PG+ GE GP GP
Sbjct: 773 KGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP 832

Query: 475 KGY------------RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG----NGT 518
            G+            +G++G  G +G  GAPGP GP G PG  G  G  GP G     G 
Sbjct: 833 AGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP 892

Query: 519 EGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEG 578
            G  GFPG  G  G PG NG  G PG  G  G+ G  G    D  P G  G  G +GP G
Sbjct: 893 PGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA-RGDSGPPGRAGEPGLQGPAG 951

Query: 579 P---------QGPPGHQGPPGP 591
           P          GP G +GPPGP
Sbjct: 952 PPGEKGEPGDDGPSGAEGPPGP 973



 Score =  291 bits (745), Expect = 2e-78
 Identities = 159/352 (45%), Positives = 193/352 (54%), Gaps = 20/352 (5%)

Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRG---EKGS 312
           +G  G +G+PG  G +G PG  GE+G+ G  G PG +GP+G  G +G  G+RG   + G 
Sbjct: 464 KGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGL 523

Query: 313 RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372
            GPKG  GE+G  G+ G  G  G+ G PG PG  G+ G  G  G  GP+G  G  G  GE
Sbjct: 524 AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE 583

Query: 373 KGEPG------ADGEAGRPGSSGPSGDEGQPGE------PGPPGEKGEAGDEGNPGPDGA 420
            G PG      A G+ G  G  GP G  G+PG+      PG PG +G  G +G  G  G 
Sbjct: 584 DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP 643

Query: 421 PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480
           PG  G  GERG +G PG  G +G PG  GP G+ G+ G  GVPG+ G  G +GP+G RG 
Sbjct: 644 PGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 703

Query: 481 EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGT 539
            G  GS GA+G  GP G PG PG  G +G  GPAG  G +G PG  G PG RGA GI G 
Sbjct: 704 PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP 763

Query: 540 KGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
           KG  G  G++G  G PG D      RG+ G  G  GP G  G  G  GPPGP
Sbjct: 764 KGDRGDVGEKGPEGAPGKDGG----RGLTGPIGPPGPAGANGEKGEVGPPGP 811



 Score =  291 bits (744), Expect = 3e-78
 Identities = 163/379 (43%), Positives = 190/379 (50%), Gaps = 43/379 (11%)

Query: 255  ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314
            A G  G  G PG  G  G  G PGE+GE G PG  G  GP G  G  G KG +GE G +G
Sbjct: 799  ANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKG 858

Query: 315  ------PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFG 368
                  P+G  G  G +G  GV G KG  G  G PG  G PG  G  GPPG  G+PG  G
Sbjct: 859  DAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG 918

Query: 369  LKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPG 428
              G  G+ G  G  G  G  G +G+ G  G  GPPGEKGE GD+G  G +G PG +G  G
Sbjct: 919  PPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAG 978

Query: 429  ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEG 488
            +RG  G PG RG RG PG  GP G+ G++G  G  GD G  GP+GP G  G  G PG EG
Sbjct: 979  QRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREG 1038

Query: 489  ARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGL--- 545
            + GA GP G  G  G+ G+RGE G    G  G PG PG PG  G  G  G +G  G    
Sbjct: 1039 SPGADGPPGRDGAAGVKGDRGETGAV--GAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1096

Query: 546  ------------------KGDEGEAGDPGDDN--------------NDIAPRGVKGAKGY 573
                              +GD+GEAG+PG+                    P G +GA G 
Sbjct: 1097 MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP 1156

Query: 574  RGPEGPQGPPGHQGPPGPD 592
             GP GP+GPPG  GP G D
Sbjct: 1157 AGPSGPRGPPGPVGPSGKD 1175



 Score =  290 bits (743), Expect = 4e-78
 Identities = 160/362 (44%), Positives = 193/362 (53%), Gaps = 30/362 (8%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            RG  G  G  GF+G  G PG PGE G+ GD G PG+ G  G  G +GE+G  GE+GS G 
Sbjct: 653  RGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGA 712

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375
            +G +G +G  G  G DG KG  G  G PG +G PG   +QG PG +G  G  G KG++G+
Sbjct: 713  QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPG---LQGMPGERGAAGIAGPKGDRGD 769

Query: 376  PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGT 435
             G  G  G PG  G  G  G  G PGP G  GE G+ G PGP G+ G RG PGERG  G 
Sbjct: 770  VGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGP 829

Query: 436  PGTR------------GPRGDPGEAGPQGDQGREGPVGVPGDPGEAGP---IGPKGYRGD 480
            PG              G +G+ GEAG +GD G  GP G  G PG  GP    GPKG RG 
Sbjct: 830  PGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGA 889

Query: 481  EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGT 539
            +GPPG+ G  GA G  GPPG  G  G  G  GP+G +G +G  G  G PG  G PG+ G 
Sbjct: 890  QGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGP 949

Query: 540  KGYPGLKGDEGEAGDPGDD-----------NNDIAPRGVKGAKGYRGPEGPQGPPGHQGP 588
             G PG KG+ G+ G  G +              +   G +G +G+ G  GP G PG QG 
Sbjct: 950  AGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 1009

Query: 589  PG 590
            PG
Sbjct: 1010 PG 1011



 Score =  285 bits (729), Expect = 2e-76
 Identities = 162/355 (45%), Positives = 184/355 (51%), Gaps = 30/355 (8%)

Query: 255 ARGPPGLRGDPGFEGERGKPGL---PGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG 311
           A G  G  G PG +G RG+PG+   PG KG  G+PG+ G+ G  G  G++G  G  GE G
Sbjct: 580 APGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETG 639

Query: 312 SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKG 371
           + GP G  G  G+RG  G  G  G  G PG PG  G  G  G QG PG  G PG  G +G
Sbjct: 640 AAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRG 699

Query: 372 EKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERG 431
           E+G PG   E G PG+ G  G  G PG PG  G KG +G  G PG  G PG +G PGERG
Sbjct: 700 ERGFPG---ERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERG 756

Query: 432 PRGTPGTRGPRGDPGEAGPQGDQGRE------------GPVGVPGDPGEAGPIGPKGYRG 479
             G  G +G RGD GE GP+G  G++            GP G  G+ GE GP GP G  G
Sbjct: 757 AAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAG 816

Query: 480 DEGPPGSEGARGAPGP---AGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGI 536
             G PG  G  G PGP   AGPPG  G  G +GE G AG   +G  G PG  G  GAPG 
Sbjct: 817 ARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQ--KGDAGAPGPQGPSGAPGP 874

Query: 537 NGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
            G  G  G KG  G  G PG         G  GA G  GP G  G PG  GPPGP
Sbjct: 875 QGPTGVTGPKGARGAQGPPG-------ATGFPGAAGRVGPPGSNGNPGPPGPPGP 922



 Score =  282 bits (722), Expect = 1e-75
 Identities = 165/374 (44%), Positives = 189/374 (50%), Gaps = 39/374 (10%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            GPPG  G PG +GE+G+ G  G+ G  G  G  G  GP G  G+ G KG+RG +G  G  
Sbjct: 837  GPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGAT 896

Query: 317  GYKGEKGK---------------RGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361
            G+ G  G+                G  G DG KG  G  G PG  G PG  G  GPPG K
Sbjct: 897  GFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEK 956

Query: 362  GDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQ---PGEPGPPGEKGE------AGDE 412
            G+PG  G  G +G PG  G AG+ G  G  G  G+   PG PGP GE G+      +GD 
Sbjct: 957  GEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDR 1016

Query: 413  GNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPV---GVPGDPGEA 469
            G PGP G PG  G  GE G  G+PG  GP G  G AG +GD+G  G V   G PG PG  
Sbjct: 1017 GPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSP 1076

Query: 470  GPIGPKGYRGDE---------GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTE 519
            GP GP G +GD          GP G  GARG  GP GP GD G  GE GE G  G+ G  
Sbjct: 1077 GPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFT 1136

Query: 520  GFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDD--NNDIAPRGVKGAKGYRGPE 577
            G  G PG PG  G  G +G  G  G +G  G  G  G D  N    P G  G +G  G  
Sbjct: 1137 GLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGET 1196

Query: 578  GPQGPPGHQGPPGP 591
            GP GPPG+ GPPGP
Sbjct: 1197 GPAGPPGNPGPPGP 1210



 Score =  281 bits (718), Expect = 3e-75
 Identities = 163/384 (42%), Positives = 195/384 (50%), Gaps = 48/384 (12%)

Query: 255  ARGPPGLRGDPGFE---------------GERGKPGLPGE------------KGEAGDPG 287
            A+GPPGL+G PG                 GE+G  G PG+             G AG  G
Sbjct: 742  AQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANG 801

Query: 288  RPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKG 347
              G++GP G  G  G +G+ GE+G  GP G  G  G  G DG  G KGE G  G  G  G
Sbjct: 802  EKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG 861

Query: 348  SPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSS---GPSGDEGQPGEPGPPG 404
            +PG  G  G PGP+G  G  G KG +G  G  G  G PG++   GP G  G PG PGPPG
Sbjct: 862  APGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 921

Query: 405  EKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEA------GPQGDQGREG 458
              G+ G +G  G  G PG  G PG +GP G PG +G  GD G +      GPQG  G+ G
Sbjct: 922  PSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRG 981

Query: 459  PVGVPGDPGE---AGPIGPKGYRGDEGPPGSEGARGAPGPAGPP------GDPGLMGERG 509
             VG+PG  GE    G  GP G  G +G PG+ G RG PGP GPP      G+PG  G  G
Sbjct: 982  IVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPG 1041

Query: 510  EDGPAG-NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGD--DNNDIAPRG 566
             DGP G +G  G  G  G  G  GAPG  G  G PG  G  G+ GD G+      + P G
Sbjct: 1042 ADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSG 1101

Query: 567  VKGAKGYRGPEGPQGPPGHQGPPG 590
              GA+G +GP+GP+G  G  G PG
Sbjct: 1102 PAGARGIQGPQGPRGDKGEAGEPG 1125



 Score =  275 bits (704), Expect = 1e-73
 Identities = 162/369 (43%), Positives = 190/369 (51%), Gaps = 55/369 (14%)

Query: 263 GDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEK 322
           G PG +G++G+PG    K   G  G PG  GP G QG +G++G +GEKG+ GP+G  GE 
Sbjct: 98  GQPGPKGQKGEPG--DIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 155

Query: 323 GKRGIDGVDGVKGEMGYPGLPG---CKGSPGFD------------GIQGPPGPKGDPGAF 367
           G  G  G  G  G  G PGL G    + + GFD            G  GP GP+G PG  
Sbjct: 156 GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 215

Query: 368 GLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAG------DEGNPGPDGA- 420
           G  G +G  G  GE G PG SGP G  G PG PG PG+ GEAG      + G PGP GA 
Sbjct: 216 GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGAR 275

Query: 421 --PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREG---------PVGVPGDPGEA 469
             PG  G PG +G RG PG  G +G+ G  G +G+ G  G         P G+PG+ G  
Sbjct: 276 GFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRT 335

Query: 470 GPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-------NGTEGFP 522
           GP G  G RG++G PG  G  G  GPAG PG PG  G +GE GP G        G  G P
Sbjct: 336 GPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEP 395

Query: 523 GFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGP 582
           G PG PG  GA G  GT G PG KG  G            AP G+ GA G+ GP GP GP
Sbjct: 396 GTPGSPGPAGASGNPGTDGIPGAKGSAG------------AP-GIAGAPGFPGPRGPPGP 442

Query: 583 PGHQGPPGP 591
            G  GP GP
Sbjct: 443 QGATGPLGP 451



 Score =  274 bits (701), Expect = 3e-73
 Identities = 156/360 (43%), Positives = 188/360 (52%), Gaps = 24/360 (6%)

Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
           +GP G +G  G  G++G+ G PG +G  G+PG PG+ GP G  G  G  G  G   ++  
Sbjct: 125 QGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMA 184

Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK-- 373
            G+  + G   +  + G  G MG  G PG  G+PG  G QG PG  G+PG  G  G +  
Sbjct: 185 GGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGP 244

Query: 374 ----GEPGADGEAGRPGSS---GPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGG 426
               G+PG DGEAG+PG +   GP G +G  G PG PG  G  G  G PG DGA GE G 
Sbjct: 245 PGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGA 304

Query: 427 PGER------GPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480
           PG +      G  G+PG  GPRG PGE G  G  G  G  G  G PG AGP GP G  G 
Sbjct: 305 PGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGG 364

Query: 481 EGPPGSEGARGAPGPAGPPGDPGLMGERGE------DGPAG-NGTEGFPGFPGYPGNRGA 533
            G PG+ GA+G  GP G  G  G  G RGE       GPAG +G  G  G PG  G+ GA
Sbjct: 365 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA 424

Query: 534 PGINGTKGYPGLKGDEGEAGDPG--DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
           PGI G  G+PG +G  G  G  G           G+ G KG +GP+G  GP G QG PGP
Sbjct: 425 PGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGP 484



 Score =  273 bits (699), Expect = 5e-73
 Identities = 168/413 (40%), Positives = 199/413 (48%), Gaps = 75/413 (18%)

Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP------------------ 294
           Q   G  G RGD G +GE+G PG  G  GE G PG PG  GP                  
Sbjct: 125 QGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMA 184

Query: 295 ---------------VGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGY 339
                           G  G  G +G  G  G+ GP+G++G  G+ G  GV G  G  G 
Sbjct: 185 GGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGP 244

Query: 340 PGLPGC------KGSPGFDGIQGPPGPK------GDPGAFGLKGEKGEPGAD---GEAGR 384
           PG PG        G PG  G +GPPGP+      G PG  G+KG +G PG D   GEAG 
Sbjct: 245 PGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGA 304

Query: 385 PGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGD 444
           PG  G SG  G+ G PGP G +G  G+ G  GP GA G RG  G+ GP G PG  GP G 
Sbjct: 305 PGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGG 364

Query: 445 P---------GEAGP---QGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGA 492
           P         GEAGP   +G +G +GP G PG PG  GP G  G  G +G PG++G+ GA
Sbjct: 365 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA 424

Query: 493 PGPAGPPGDPGLMGERGEDGPAG-------NGTEGFPGFPGYPGNRGAPGINGTKGYPGL 545
           PG AG PG PG  G  G  G  G        G  G  GF G  G +G PG  G +G PG 
Sbjct: 425 PGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGP 484

Query: 546 KGDEGEAGDPGDDN--NDIAPRGVKGAKGYR------GPEGPQGPPGHQGPPG 590
            G+EG+ G  G+      I P G +GA G R      G  GP+G PG +GP G
Sbjct: 485 AGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSG 537



 Score =  273 bits (699), Expect = 5e-73
 Identities = 156/358 (43%), Positives = 180/358 (50%), Gaps = 26/358 (7%)

Query: 253  QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312
            Q   G PG +G  G  G +G  G  G  G  G PG  G +GP G  G  G  G  G  G 
Sbjct: 866  QGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGK 925

Query: 313  RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK---GDPGAFGL 369
             GPKG +G+ G  G  G  G++G  G PG  G  G  G  G +GPPGP+   G  G  GL
Sbjct: 926  DGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGL 985

Query: 370  KGEKGE------PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD---EGNPGPDGA 420
             G++GE      PG  GE G+ G+ G SGD G PG  GPPG  G AG+   EG+PG DG 
Sbjct: 986  PGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP 1045

Query: 421  PGERGGPGERGPR------GTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGP 474
            PG  G  G +G R      G PG  GP G PG AGP G QG  G  G  G  G +GP G 
Sbjct: 1046 PGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGA 1105

Query: 475  KGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGA 533
            +G +G +GP G +G  G PG  G  G  G  G +G  GP G +G +G  G  G  G RG 
Sbjct: 1106 RGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGP 1165

Query: 534  PGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
            PG  G  G  G  G  G  G PG       PRG  G  G  GP G  GPPG  GPPGP
Sbjct: 1166 PGPVGPSGKDGANGIPGPIGPPG-------PRGRSGETGPAGPPGNPGPPGPPGPPGP 1216



 Score =  186 bits (472), Expect = 1e-46
 Identities = 105/257 (40%), Positives = 129/257 (50%), Gaps = 52/257 (20%)

Query: 387 SSGPSGDEGQPGEP----------GPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436
           +SG  G +GQ GEP          GPPG +G AG++G  G  G  GE+G PG RG  G P
Sbjct: 96  ASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 155

Query: 437 GTRGPRGDPGEAGPQGD---------------------------QGREGPVGVPGDPGEA 469
           GT G  G PG  GP G                            QG  GP+G  G PG A
Sbjct: 156 GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 215

Query: 470 GPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDG----------PAGNGTE 519
           G  GP+G++G+ G PG  G  G  GP GPPG PG  G+ GE G          P   G  
Sbjct: 216 GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGAR 275

Query: 520 GFPGFPGYP---GNRGAPGINGTKGYPGLKGDEGEAGDPGDDNN--DIAPRGVKGAKGYR 574
           GFPG PG P   G+RG PG++G KG  G  G +GE+G PG++ +   + PRG+ G +G  
Sbjct: 276 GFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRT 335

Query: 575 GPEGPQGPPGHQGPPGP 591
           GP G  G  G+ G PGP
Sbjct: 336 GPAGAAGARGNDGQPGP 352



 Score =  120 bits (302), Expect = 5e-27
 Identities = 77/179 (43%), Positives = 87/179 (48%), Gaps = 33/179 (18%)

Query: 425 GGPGERGPRGTPGTR----GPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480
           G PG +G +G PG      GP+G PG   PQG  G +GP G  GD GE G  GP   RG 
Sbjct: 98  GQPGPKGQKGEPGDIKDIVGPKGPPG---PQGPAGEQGPRGDRGDKGEKGAPGP---RGR 151

Query: 481 EGPPGSEGARGAPGPAGPPGDPGLMGE------RGEDGPAGNGTEGFPGFPGYP-GNRGA 533
           +G PG+ G  G PGP GPPG PGL G        G D  AG    G    P  P G RG 
Sbjct: 152 DGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGP 211

Query: 534 PGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592
           PG  G  G  G +G+ GE G+PG                  GP GP+GPPG  G PG D
Sbjct: 212 PGPAGAPGPQGFQGNPGEPGEPG----------------VSGPMGPRGPPGPPGKPGDD 254



 Score = 88.6 bits (218), Expect = 3e-17
 Identities = 57/140 (40%), Positives = 65/140 (46%), Gaps = 17/140 (12%)

Query: 467 GEAGPIGPKGYRGDEGPPGSEGARGAPGP----AGPPGDPGLMGERGEDGPAGN------ 516
           GE  PI P       G PG +G +G PG      GP G PG  G  GE GP G+      
Sbjct: 83  GECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGE 142

Query: 517 ----GTEGFPGFPGYPGNRGAPGINGTKGYPGLKGD-EGEAGDPGDDNNDIAPRGVKGAK 571
               G  G  G PG PGN G PG  G  G PGL G+   +     D+    A  GV   +
Sbjct: 143 KGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV--MQ 200

Query: 572 GYRGPEGPQGPPGHQGPPGP 591
           G  GP GP+GPPG  G PGP
Sbjct: 201 GPMGPMGPRGPPGPAGAPGP 220


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score =  309 bits (792), Expect = 8e-84
 Identities = 182/369 (49%), Positives = 206/369 (55%), Gaps = 41/369 (11%)

Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
           RGP GL G  G  G+ G+PG PG  G  G  GRPGD GP   QG  G  G+ GE G  GP
Sbjct: 464 RGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGP---QGKVGPSGAPGEDGRPGP 520

Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375
            G +G +G+ G+ G  G KG  G PG  G KG PG  G++G PG  G+ GA G  G  G 
Sbjct: 521 PGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGP 580

Query: 376 PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPG------ERGGPGE 429
            G  GE G PG   PSG +G PG PGPPGE G+ GD+G PG  GAPG      ERG PGE
Sbjct: 581 AGERGEQGAPG---PSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE 637

Query: 430 RG---------PRG---TPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY 477
           RG         PRG   TPGT GP+G  G AGP G QG  G  G+PG+ G AG  GPKG 
Sbjct: 638 RGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGD 697

Query: 478 RGD------EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGN 530
           RGD      EG PG +G RG  GP GPPG  G  GE+GE GP G  G+ G  G PG  G 
Sbjct: 698 RGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGE 757

Query: 531 RGAP------GINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGP---EGPQG 581
            G P      G  G  G PG KG++GEAG  GD      P+G  GA G +GP    GP+G
Sbjct: 758 TGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAP-GPQGPSGAPGPQGPTGVTGPKG 816

Query: 582 PPGHQGPPG 590
             G QGPPG
Sbjct: 817 ARGAQGPPG 825



 Score =  300 bits (767), Expect = 6e-81
 Identities = 169/347 (48%), Positives = 191/347 (55%), Gaps = 27/347 (7%)

Query: 256 RGPPGLRGDPGFEGERGKPGLPGE------KGEAGDPGRPGDLGPVGYQGMKGEKGSRGE 309
           RG PG RG PG +G +G  GLPG       KG +G  G PG  GP G QGM GE+G+ G 
Sbjct: 632 RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 691

Query: 310 KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGL 369
            G +G +G  GEKG  G  G DG +G  G  G PG  G+ G  G  GPPGP G  GA G 
Sbjct: 692 AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA 751

Query: 370 KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGE 429
            GE+GE G  G AG  G  G  G  G  GE G  G+KG+AG  G  GP GAPG +G  G 
Sbjct: 752 PGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGV 811

Query: 430 RGPRGTPGTRGP---RGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGS 486
            GP+G  G +GP    G PG AG  G  G  G  G PG PG +G  GPKG RGD GPPG 
Sbjct: 812 TGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGR 871

Query: 487 EGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNR---GAPGINGTKGYP 543
            G  G  GPAGPPG+    GE G+DGP  +G EG PG  G  G R   G PG  G +G+P
Sbjct: 872 AGEPGLQGPAGPPGE---KGEPGDDGP--SGAEGPPGPQGLAGQRGIVGLPGQRGERGFP 926

Query: 544 GLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           GL G  GE G           +G  GA G RGP GP GPPG  GP G
Sbjct: 927 GLPGPSGEPG----------KQGAPGASGDRGPPGPVGPPGLTGPAG 963



 Score =  298 bits (763), Expect = 2e-80
 Identities = 163/345 (47%), Positives = 187/345 (54%), Gaps = 14/345 (4%)

Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
           RGPPG  G PG +G +G PG PGE G +G  G  G  GP G  G  GE G  G+ G RGP
Sbjct: 140 RGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGP 199

Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375
            G +G +G  G  G+ GVKG  GYPGL G KG  G  G++G  G  G+ G+ G  G +G 
Sbjct: 200 PGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGL 259

Query: 376 PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGT 435
           PG  G  G  G++G  G++GQPG  GPPG  G AG  G PG  GA GE G  G RGP G 
Sbjct: 260 PGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGA 319

Query: 436 PGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGP---IGPKGYRGDEGPPGSEGARGA 492
            G RG  G PG  GP G  G  G  G+PG  G AG     G  G+ G  GPPG +GA G 
Sbjct: 320 QGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGP 379

Query: 493 PGPAGPPGDPGLMGERGEDGPAGN----GTEGFPGFPGYPGNRGA---PGINGTKGYPGL 545
            GP G  G+PG+ G +GE GP G     G +G PG  G  G RGA   PG  G  G PG 
Sbjct: 380 LGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGE 439

Query: 546 KGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           +G  G  G PG D       G KGA G RGP G  GP G  G PG
Sbjct: 440 RGAPGNRGFPGQD----GLAGPKGAPGERGPSGLAGPKGANGDPG 480



 Score =  292 bits (747), Expect = 1e-78
 Identities = 165/360 (45%), Positives = 195/360 (54%), Gaps = 36/360 (10%)

Query: 255 ARGPPGLRGDPGFEGERGKPGL---PGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG 311
           A G PG  G PG +G  G PG+   PG  G  G PG  G  GP+G +G  GE G  G KG
Sbjct: 337 ASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKG 396

Query: 312 SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKG 371
            +GPKG  G  G +G  G  G +G+ G  G PG  G  G  G +G PG +G PG  GL G
Sbjct: 397 EQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAG 456

Query: 372 EKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKG------EAGDEGNPGPDGAPGERG 425
            KG PG  G +G  G  G +GD G+PGEPG PG +G      +AG +G  GP GAPGE G
Sbjct: 457 PKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDG 516

Query: 426 GPGERGPRGT---------PGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAG------ 470
            PG  GP+G          PG +G  G+PG+AG +G  G  G  G+PG  GE G      
Sbjct: 517 RPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG 576

Query: 471 PIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGN 530
           P GP G RG++G PG  G +G PGP GPPG+ G  G++G  G A     G PG  G  G 
Sbjct: 577 PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA-----GAPGLVGPRGE 631

Query: 531 RGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           RG PG  G+ G  GL+G  G  G PG D       G KGA G  GP G QGPPG QG PG
Sbjct: 632 RGFPGERGSPGAQGLQGPRGLPGTPGTD-------GPKGASGPAGPPGAQGPPGLQGMPG 684



 Score =  291 bits (746), Expect = 2e-78
 Identities = 186/476 (39%), Positives = 215/476 (45%), Gaps = 138/476 (28%)

Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDP------------GRPGDLGP------ 294
           Q ARG PG  G PG +G RG PGL G KGEAG P            G PG +GP      
Sbjct: 203 QGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGE 262

Query: 295 ---------------------------------VGYQGMKGEKGSRGEKGSRGPKGYKGE 321
                                             G+ G  G KG  G  G+RGP+G +G 
Sbjct: 263 RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGP 322

Query: 322 KGKRGI------------DGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK-------- 361
           +G+ G              G DG+ G  G  G PG  G+PGF G +GPPGP+        
Sbjct: 323 RGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGP 382

Query: 362 ----GDPGAFGLKGE---KGEPGADGEAGRPGSSGPSGDEGQPGEP------GPPGEKGE 408
               G+PG  G KGE   KGEPG  G  G PG +G  G  G  GEP      GPPGE+G 
Sbjct: 383 KGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGA 442

Query: 409 AGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGE 468
            G+ G PG DG  G +G PGERGP G  G +G  GDPG  G  G  G  G  G PGD G 
Sbjct: 443 PGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGP 502

Query: 469 AGPIGPKGYRGDE---GPPGSEGARGAP-------------------------------- 493
            G +GP G  G++   GPPG +GARG P                                
Sbjct: 503 QGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGL 562

Query: 494 -------GPAGPPGDPGLMGERGEDG-PAGNGTEGFPGFPGYPGNRGAP---GINGTKGY 542
                  G AGPPG  G  GERGE G P  +G +G PG PG PG  G P   G+ G  G 
Sbjct: 563 PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA 622

Query: 543 PGLKGDEGEAGDPGDDNNDIA-----PRGVKGAKGYRGPE---GPQGPPGHQGPPG 590
           PGL G  GE G PG+  +  A     PRG+ G  G  GP+   GP GPPG QGPPG
Sbjct: 623 PGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPG 678



 Score =  291 bits (746), Expect = 2e-78
 Identities = 167/382 (43%), Positives = 196/382 (51%), Gaps = 44/382 (11%)

Query: 253 QPARGPPGLRGDPGFEGERGKP------GLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGS 306
           Q ARG PG+ G PG +G  G+P      GLPG  G  G PG+ G+ G  G  G  G  G 
Sbjct: 524 QGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGE 583

Query: 307 RGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366
           RGE+G+ GP G++G  G  G  G  G  G+ G PG  G  G  G  G +G PG +G PGA
Sbjct: 584 RGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGA 643

Query: 367 FGLKGEKGEP---------GADGEAGRPGSSGPSGDEGQPGEPGP---PGEKGEAGDEGN 414
            GL+G +G P         GA G AG PG+ GP G +G PGE G     G KG+ GD G 
Sbjct: 644 QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGE 703

Query: 415 PGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGP 474
            GP+GAPG+ GG G  GP G PG  G  G+ GE GP G  G  G  G PG+ GE GP GP
Sbjct: 704 KGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP 763

Query: 475 KGY------------RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG----NGT 518
            G+            +G++G  G +G  GAPGP GP G PG  G  G  GP G     G 
Sbjct: 764 AGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP 823

Query: 519 EGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEG 578
            G  GFPG  G  G PG NG  G PG  G  G+ G P     D  P G  G  G +GP G
Sbjct: 824 PGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDG-PKGARGDSGPPGRAGEPGLQGPAG 882

Query: 579 P---------QGPPGHQGPPGP 591
           P          GP G +GPPGP
Sbjct: 883 PPGEKGEPGDDGPSGAEGPPGP 904



 Score =  291 bits (745), Expect = 2e-78
 Identities = 159/352 (45%), Positives = 193/352 (54%), Gaps = 20/352 (5%)

Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRG---EKGS 312
           +G  G +G+PG  G +G PG  GE+G+ G  G PG +GP+G  G +G  G+RG   + G 
Sbjct: 395 KGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGL 454

Query: 313 RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372
            GPKG  GE+G  G+ G  G  G+ G PG PG  G+ G  G  G  GP+G  G  G  GE
Sbjct: 455 AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE 514

Query: 373 KGEPG------ADGEAGRPGSSGPSGDEGQPGE------PGPPGEKGEAGDEGNPGPDGA 420
            G PG      A G+ G  G  GP G  G+PG+      PG PG +G  G +G  G  G 
Sbjct: 515 DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP 574

Query: 421 PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480
           PG  G  GERG +G PG  G +G PG  GP G+ G+ G  GVPG+ G  G +GP+G RG 
Sbjct: 575 PGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 634

Query: 481 EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGT 539
            G  GS GA+G  GP G PG PG  G +G  GPAG  G +G PG  G PG RGA GI G 
Sbjct: 635 PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP 694

Query: 540 KGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
           KG  G  G++G  G PG D      RG+ G  G  GP G  G  G  GPPGP
Sbjct: 695 KGDRGDVGEKGPEGAPGKDGG----RGLTGPIGPPGPAGANGEKGEVGPPGP 742



 Score =  291 bits (744), Expect = 3e-78
 Identities = 163/379 (43%), Positives = 190/379 (50%), Gaps = 43/379 (11%)

Query: 255  ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314
            A G  G  G PG  G  G  G PGE+GE G PG  G  GP G  G  G KG +GE G +G
Sbjct: 730  ANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKG 789

Query: 315  ------PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFG 368
                  P+G  G  G +G  GV G KG  G  G PG  G PG  G  GPPG  G+PG  G
Sbjct: 790  DAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG 849

Query: 369  LKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPG 428
              G  G+ G  G  G  G  G +G+ G  G  GPPGEKGE GD+G  G +G PG +G  G
Sbjct: 850  PPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAG 909

Query: 429  ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEG 488
            +RG  G PG RG RG PG  GP G+ G++G  G  GD G  GP+GP G  G  G PG EG
Sbjct: 910  QRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREG 969

Query: 489  ARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGL--- 545
            + GA GP G  G  G+ G+RGE G    G  G PG PG PG  G  G  G +G  G    
Sbjct: 970  SPGADGPPGRDGAAGVKGDRGETGAV--GAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1027

Query: 546  ------------------KGDEGEAGDPGDDN--------------NDIAPRGVKGAKGY 573
                              +GD+GEAG+PG+                    P G +GA G 
Sbjct: 1028 MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP 1087

Query: 574  RGPEGPQGPPGHQGPPGPD 592
             GP GP+GPPG  GP G D
Sbjct: 1088 AGPSGPRGPPGPVGPSGKD 1106



 Score =  290 bits (743), Expect = 4e-78
 Identities = 160/362 (44%), Positives = 193/362 (53%), Gaps = 30/362 (8%)

Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
           RG  G  G  GF+G  G PG PGE G+ GD G PG+ G  G  G +GE+G  GE+GS G 
Sbjct: 584 RGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGA 643

Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375
           +G +G +G  G  G DG KG  G  G PG +G PG   +QG PG +G  G  G KG++G+
Sbjct: 644 QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPG---LQGMPGERGAAGIAGPKGDRGD 700

Query: 376 PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGT 435
            G  G  G PG  G  G  G  G PGP G  GE G+ G PGP G+ G RG PGERG  G 
Sbjct: 701 VGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGP 760

Query: 436 PGTR------------GPRGDPGEAGPQGDQGREGPVGVPGDPGEAGP---IGPKGYRGD 480
           PG              G +G+ GEAG +GD G  GP G  G PG  GP    GPKG RG 
Sbjct: 761 PGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGA 820

Query: 481 EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGT 539
           +GPPG+ G  GA G  GPPG  G  G  G  GP+G +G +G  G  G PG  G PG+ G 
Sbjct: 821 QGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGP 880

Query: 540 KGYPGLKGDEGEAGDPGDD-----------NNDIAPRGVKGAKGYRGPEGPQGPPGHQGP 588
            G PG KG+ G+ G  G +              +   G +G +G+ G  GP G PG QG 
Sbjct: 881 AGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 940

Query: 589 PG 590
           PG
Sbjct: 941 PG 942



 Score =  285 bits (729), Expect = 2e-76
 Identities = 162/355 (45%), Positives = 184/355 (51%), Gaps = 30/355 (8%)

Query: 255 ARGPPGLRGDPGFEGERGKPGL---PGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG 311
           A G  G  G PG +G RG+PG+   PG KG  G+PG+ G+ G  G  G++G  G  GE G
Sbjct: 511 APGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETG 570

Query: 312 SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKG 371
           + GP G  G  G+RG  G  G  G  G PG PG  G  G  G QG PG  G PG  G +G
Sbjct: 571 AAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRG 630

Query: 372 EKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERG 431
           E+G PG   E G PG+ G  G  G PG PG  G KG +G  G PG  G PG +G PGERG
Sbjct: 631 ERGFPG---ERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERG 687

Query: 432 PRGTPGTRGPRGDPGEAGPQGDQGRE------------GPVGVPGDPGEAGPIGPKGYRG 479
             G  G +G RGD GE GP+G  G++            GP G  G+ GE GP GP G  G
Sbjct: 688 AAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAG 747

Query: 480 DEGPPGSEGARGAPGP---AGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGI 536
             G PG  G  G PGP   AGPPG  G  G +GE G AG   +G  G PG  G  GAPG 
Sbjct: 748 ARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQ--KGDAGAPGPQGPSGAPGP 805

Query: 537 NGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
            G  G  G KG  G  G PG         G  GA G  GP G  G PG  GPPGP
Sbjct: 806 QGPTGVTGPKGARGAQGPPG-------ATGFPGAAGRVGPPGSNGNPGPPGPPGP 853



 Score =  282 bits (722), Expect = 1e-75
 Identities = 165/374 (44%), Positives = 189/374 (50%), Gaps = 39/374 (10%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            GPPG  G PG +GE+G+ G  G+ G  G  G  G  GP G  G+ G KG+RG +G  G  
Sbjct: 768  GPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGAT 827

Query: 317  GYKGEKGK---------------RGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361
            G+ G  G+                G  G DG KG  G  G PG  G PG  G  GPPG K
Sbjct: 828  GFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEK 887

Query: 362  GDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQ---PGEPGPPGEKGE------AGDE 412
            G+PG  G  G +G PG  G AG+ G  G  G  G+   PG PGP GE G+      +GD 
Sbjct: 888  GEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDR 947

Query: 413  GNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPV---GVPGDPGEA 469
            G PGP G PG  G  GE G  G+PG  GP G  G AG +GD+G  G V   G PG PG  
Sbjct: 948  GPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSP 1007

Query: 470  GPIGPKGYRGDE---------GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTE 519
            GP GP G +GD          GP G  GARG  GP GP GD G  GE GE G  G+ G  
Sbjct: 1008 GPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFT 1067

Query: 520  GFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDD--NNDIAPRGVKGAKGYRGPE 577
            G  G PG PG  G  G +G  G  G +G  G  G  G D  N    P G  G +G  G  
Sbjct: 1068 GLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGET 1127

Query: 578  GPQGPPGHQGPPGP 591
            GP GPPG+ GPPGP
Sbjct: 1128 GPAGPPGNPGPPGP 1141



 Score =  281 bits (718), Expect = 3e-75
 Identities = 163/384 (42%), Positives = 195/384 (50%), Gaps = 48/384 (12%)

Query: 255  ARGPPGLRGDPGFE---------------GERGKPGLPGE------------KGEAGDPG 287
            A+GPPGL+G PG                 GE+G  G PG+             G AG  G
Sbjct: 673  AQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANG 732

Query: 288  RPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKG 347
              G++GP G  G  G +G+ GE+G  GP G  G  G  G DG  G KGE G  G  G  G
Sbjct: 733  EKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG 792

Query: 348  SPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSS---GPSGDEGQPGEPGPPG 404
            +PG  G  G PGP+G  G  G KG +G  G  G  G PG++   GP G  G PG PGPPG
Sbjct: 793  APGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 852

Query: 405  EKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEA------GPQGDQGREG 458
              G+ G +G  G  G PG  G PG +GP G PG +G  GD G +      GPQG  G+ G
Sbjct: 853  PSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRG 912

Query: 459  PVGVPGDPGE---AGPIGPKGYRGDEGPPGSEGARGAPGPAGPP------GDPGLMGERG 509
             VG+PG  GE    G  GP G  G +G PG+ G RG PGP GPP      G+PG  G  G
Sbjct: 913  IVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPG 972

Query: 510  EDGPAG-NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGD--DNNDIAPRG 566
             DGP G +G  G  G  G  G  GAPG  G  G PG  G  G+ GD G+      + P G
Sbjct: 973  ADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSG 1032

Query: 567  VKGAKGYRGPEGPQGPPGHQGPPG 590
              GA+G +GP+GP+G  G  G PG
Sbjct: 1033 PAGARGIQGPQGPRGDKGEAGEPG 1056



 Score =  274 bits (701), Expect = 3e-73
 Identities = 156/360 (43%), Positives = 188/360 (52%), Gaps = 24/360 (6%)

Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
           +GP G +G  G  G++G+ G PG +G  G+PG PG+ GP G  G  G  G  G   ++  
Sbjct: 56  QGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMA 115

Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK-- 373
            G+  + G   +  + G  G MG  G PG  G+PG  G QG PG  G+PG  G  G +  
Sbjct: 116 GGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGP 175

Query: 374 ----GEPGADGEAGRPGSS---GPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGG 426
               G+PG DGEAG+PG +   GP G +G  G PG PG  G  G  G PG DGA GE G 
Sbjct: 176 PGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGA 235

Query: 427 PGER------GPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480
           PG +      G  G+PG  GPRG PGE G  G  G  G  G  G PG AGP GP G  G 
Sbjct: 236 PGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGG 295

Query: 481 EGPPGSEGARGAPGPAGPPGDPGLMGERGE------DGPAG-NGTEGFPGFPGYPGNRGA 533
            G PG+ GA+G  GP G  G  G  G RGE       GPAG +G  G  G PG  G+ GA
Sbjct: 296 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA 355

Query: 534 PGINGTKGYPGLKGDEGEAGDPG--DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
           PGI G  G+PG +G  G  G  G           G+ G KG +GP+G  GP G QG PGP
Sbjct: 356 PGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGP 415



 Score =  273 bits (699), Expect = 5e-73
 Identities = 168/413 (40%), Positives = 199/413 (48%), Gaps = 75/413 (18%)

Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP------------------ 294
           Q   G  G RGD G +GE+G PG  G  GE G PG PG  GP                  
Sbjct: 56  QGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMA 115

Query: 295 ---------------VGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGY 339
                           G  G  G +G  G  G+ GP+G++G  G+ G  GV G  G  G 
Sbjct: 116 GGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGP 175

Query: 340 PGLPGC------KGSPGFDGIQGPPGPK------GDPGAFGLKGEKGEPGAD---GEAGR 384
           PG PG        G PG  G +GPPGP+      G PG  G+KG +G PG D   GEAG 
Sbjct: 176 PGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGA 235

Query: 385 PGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGD 444
           PG  G SG  G+ G PGP G +G  G+ G  GP GA G RG  G+ GP G PG  GP G 
Sbjct: 236 PGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGG 295

Query: 445 P---------GEAGP---QGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGA 492
           P         GEAGP   +G +G +GP G PG PG  GP G  G  G +G PG++G+ GA
Sbjct: 296 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA 355

Query: 493 PGPAGPPGDPGLMGERGEDGPAG-------NGTEGFPGFPGYPGNRGAPGINGTKGYPGL 545
           PG AG PG PG  G  G  G  G        G  G  GF G  G +G PG  G +G PG 
Sbjct: 356 PGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGP 415

Query: 546 KGDEGEAGDPGDDN--NDIAPRGVKGAKGYR------GPEGPQGPPGHQGPPG 590
            G+EG+ G  G+      I P G +GA G R      G  GP+G PG +GP G
Sbjct: 416 AGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSG 468



 Score =  273 bits (699), Expect = 5e-73
 Identities = 156/358 (43%), Positives = 180/358 (50%), Gaps = 26/358 (7%)

Query: 253  QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312
            Q   G PG +G  G  G +G  G  G  G  G PG  G +GP G  G  G  G  G  G 
Sbjct: 797  QGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGK 856

Query: 313  RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK---GDPGAFGL 369
             GPKG +G+ G  G  G  G++G  G PG  G  G  G  G +GPPGP+   G  G  GL
Sbjct: 857  DGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGL 916

Query: 370  KGEKGE------PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD---EGNPGPDGA 420
             G++GE      PG  GE G+ G+ G SGD G PG  GPPG  G AG+   EG+PG DG 
Sbjct: 917  PGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP 976

Query: 421  PGERGGPGERGPR------GTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGP 474
            PG  G  G +G R      G PG  GP G PG AGP G QG  G  G  G  G +GP G 
Sbjct: 977  PGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGA 1036

Query: 475  KGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGA 533
            +G +G +GP G +G  G PG  G  G  G  G +G  GP G +G +G  G  G  G RG 
Sbjct: 1037 RGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGP 1096

Query: 534  PGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
            PG  G  G  G  G  G  G PG       PRG  G  G  GP G  GPPG  GPPGP
Sbjct: 1097 PGPVGPSGKDGANGIPGPIGPPG-------PRGRSGETGPAGPPGNPGPPGPPGPPGP 1147



 Score =  273 bits (698), Expect = 6e-73
 Identities = 161/367 (43%), Positives = 189/367 (51%), Gaps = 55/367 (14%)

Query: 265 PGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGK 324
           PG +G++G+PG    K   G  G PG  GP G QG +G++G +GEKG+ GP+G  GE G 
Sbjct: 31  PGPKGQKGEPG--DIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT 88

Query: 325 RGIDGVDGVKGEMGYPGLPG---CKGSPGFD------------GIQGPPGPKGDPGAFGL 369
            G  G  G  G  G PGL G    + + GFD            G  GP GP+G PG  G 
Sbjct: 89  PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGA 148

Query: 370 KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAG------DEGNPGPDGA--- 420
            G +G  G  GE G PG SGP G  G PG PG PG+ GEAG      + G PGP GA   
Sbjct: 149 PGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGF 208

Query: 421 PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREG---------PVGVPGDPGEAGP 471
           PG  G PG +G RG PG  G +G+ G  G +G+ G  G         P G+PG+ G  GP
Sbjct: 209 PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGP 268

Query: 472 IGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-------NGTEGFPGF 524
            G  G RG++G PG  G  G  GPAG PG PG  G +GE GP G        G  G PG 
Sbjct: 269 AGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGT 328

Query: 525 PGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPG 584
           PG PG  GA G  GT G PG KG  G            AP G+ GA G+ GP GP GP G
Sbjct: 329 PGSPGPAGASGNPGTDGIPGAKGSAG------------AP-GIAGAPGFPGPRGPPGPQG 375

Query: 585 HQGPPGP 591
             GP GP
Sbjct: 376 ATGPLGP 382



 Score =  176 bits (445), Expect = 1e-43
 Identities = 101/254 (39%), Positives = 125/254 (49%), Gaps = 61/254 (24%)

Query: 399 EPGPPGEKGEAGD-------EGNPGPDGAPGERGGPGERGPR---------------GTP 436
           +PGP G+KGE GD       +G PGP G  GE+G  G+RG +               GTP
Sbjct: 30  QPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTP 89

Query: 437 GTRGPRGDPGEAGPQG------------------------DQGREGPVGVPGDPGEAGPI 472
           G  GP G PG  GP G                         QG  GP+G  G PG AG  
Sbjct: 90  GNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAP 149

Query: 473 GPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDG----------PAGNGTEGFP 522
           GP+G++G+ G PG  G  G  GP GPPG PG  G+ GE G          P   G  GFP
Sbjct: 150 GPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFP 209

Query: 523 GFPGYP---GNRGAPGINGTKGYPGLKGDEGEAGDPGDDNN--DIAPRGVKGAKGYRGPE 577
           G PG P   G+RG PG++G KG  G  G +GE+G PG++ +   + PRG+ G +G  GP 
Sbjct: 210 GTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPA 269

Query: 578 GPQGPPGHQGPPGP 591
           G  G  G+ G PGP
Sbjct: 270 GAAGARGNDGQPGP 283



 Score =  119 bits (298), Expect = 1e-26
 Identities = 76/177 (42%), Positives = 86/177 (48%), Gaps = 33/177 (18%)

Query: 427 PGERGPRGTPGTR----GPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEG 482
           PG +G +G PG      GP+G PG   PQG  G +GP G  GD GE G  GP   RG +G
Sbjct: 31  PGPKGQKGEPGDIKDIVGPKGPPG---PQGPAGEQGPRGDRGDKGEKGAPGP---RGRDG 84

Query: 483 PPGSEGARGAPGPAGPPGDPGLMGE------RGEDGPAGNGTEGFPGFPGYP-GNRGAPG 535
            PG+ G  G PGP GPPG PGL G        G D  AG    G    P  P G RG PG
Sbjct: 85  EPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPG 144

Query: 536 INGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592
             G  G  G +G+ GE G+PG                  GP GP+GPPG  G PG D
Sbjct: 145 PAGAPGPQGFQGNPGEPGEPG----------------VSGPMGPRGPPGPPGKPGDD 185


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  308 bits (788), Expect = 2e-83
 Identities = 171/364 (46%), Positives = 196/364 (53%), Gaps = 33/364 (9%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
           GP G  G PG +G  G+PG PG KG+ G  G PG +G  G  G  GE+G RG +G  GP 
Sbjct: 419 GPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPT 478

Query: 317 GYKGEKGKRG---------IDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAF 367
           G  G  G+RG          DGV G KG  G  G PG  G  G  G  G PG  G PGA 
Sbjct: 479 GLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAK 538

Query: 368 GLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGP 427
           GL G  G PG DG+ G PG   P+G +G+PG PGPPG +G+AG  G PGP GA GE G  
Sbjct: 539 GLTGSPGSPGPDGKTGPPG---PAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA 595

Query: 428 GERGPRGTPGTRGP---------RGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYR 478
           GERG  G PG  GP         +G PG AGP G++G +GP G PG  G  GP GP G  
Sbjct: 596 GERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEA 655

Query: 479 GDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFPGYPGNRGAP 534
           G  G  G  G  GAPGP+G  G+ G  GERG  GP G     G  G PG  G  G+ GAP
Sbjct: 656 GKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAP 715

Query: 535 GINGTKGYPGLKGDEGEAG-----DPGDDNNDIAPRGVKGA---KGYRGPEGPQGPPGHQ 586
           G  G++G PGL+G  GE G      P  D  D  P+G  G+    G RG  GP GPPG  
Sbjct: 716 GAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPA 775

Query: 587 GPPG 590
           G PG
Sbjct: 776 GAPG 779



 Score =  304 bits (778), Expect = 3e-82
 Identities = 175/380 (46%), Positives = 200/380 (52%), Gaps = 45/380 (11%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            RG  G  G PGF+G  G  G PGE G+ G+ G PGDLG  G  G +GE+G  GE+G +GP
Sbjct: 631  RGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGP 690

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGP------PGPKGDPGAFGL 369
             G  G +G  G  G DG KG+ G PG PG +G+PG  G+ G       PGPKGD G  G 
Sbjct: 691  PGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGP 750

Query: 370  KGEKGEPGADGEAGRPGSSGPSGDEGQP---GEPGPPGEKGEAGDEGNPGPDGAPGERGG 426
            KG  G PG DG  G  G  GP G  G P   GE GP G  G  G  G PG  G PG  G 
Sbjct: 751  KGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGP 810

Query: 427  PGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPI---GPKGYRGDEGP 483
             G  GP G  G  G +G+PG+AG +GD G  GP G  G PG  G +   G KG RG  GP
Sbjct: 811  AGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGP 870

Query: 484  PGSEGARGA------PGP---AGPPGDPGLMGE------RGEDGPAGN-GTEGFPGFPGY 527
            PG+ G  GA      PGP   AGPPG PG  G+      RGE GPAG  G  G PG PG 
Sbjct: 871  PGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGP 930

Query: 528  PGNRGAPGINGTKGYP---------------GLKGDEGEAGDPG--DDNNDIAPRGVKGA 570
             G +G+PG +G  G P               GL G  GE G PG    + +   +G  GA
Sbjct: 931  AGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGA 990

Query: 571  KGYRGPEGPQGPPGHQGPPG 590
             G RGP GP GPPG  GPPG
Sbjct: 991  SGERGPPGPMGPPGLAGPPG 1010



 Score =  298 bits (762), Expect = 2e-80
 Identities = 169/351 (48%), Positives = 186/351 (52%), Gaps = 23/351 (6%)

Query: 257 GPPGLRGDPGFEGERGKPGLPG------EKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310
           GP G  G+PG  GERG PG PG      + GEAG  G PG  GP G +G +G  GS G +
Sbjct: 584 GPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQ 643

Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370
           G  GP G  GE GK G  GV G  G  G  G  G +G PG  G+QGPPGP G  GA G  
Sbjct: 644 GLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAP 703

Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGP---PGEKGEAGDEGNPGPDGAPGERGGP 427
           G  G  G  G  G PGS G  G +G PGE G    PG KG+ GD G  G DG+PG+ G  
Sbjct: 704 GNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVR 763

Query: 428 GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487
           G  GP G PG  G  GD GE+GP G  G  G  G PGD GE GP GP G+ G  G  G  
Sbjct: 764 GLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQP 823

Query: 488 GARGAPGPAGPPGD---PGLMGERGEDGPAGN----GTEGFPGFPGYPGNRGAPGINGTK 540
           GA+G PG AG  GD   PG  G  G  GP GN    G +G  G  G PG  G PG  G  
Sbjct: 824 GAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRV 883

Query: 541 GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
           G PG  G+ G  G PG       P G +G KG RG  GP G PG  GPPGP
Sbjct: 884 GPPGPSGNAGPPGPPG-------PAGKEGGKGPRGETGPAGRPGEVGPPGP 927



 Score =  297 bits (761), Expect = 3e-80
 Identities = 180/412 (43%), Positives = 202/412 (49%), Gaps = 77/412 (18%)

Query: 256 RGPPGLRGDPGFEG---------ERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGS 306
           RG PG RG PG +G         ERG PG  G KG  G+ GRPG+ G  G +G+ G  GS
Sbjct: 487 RGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGS 546

Query: 307 RGEKGSRGPKGYKGEKGKRGIDGVDGVKGE---MGYPGLPGCKGSPGFDGIQGPPGPKGD 363
            G  G  GP G  G+ G+ G  G  G +G+   MG+PG  G  G PG  G +G PGP G 
Sbjct: 547 PGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGA 606

Query: 364 PGAFGLKGEKG------------EPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD 411
            G  G  GE G            E G  G AG PG  G  G  G PGE G PGE+G  GD
Sbjct: 607 VGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGD 666

Query: 412 EGNPGPDGAPGERGGPGERGPRGTPGTRGPR------------GDPGEAGPQGDQGREGP 459
            G PGP GA GERG PGERG +G PG  GPR            GD G  G  G QG  G 
Sbjct: 667 LGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGL 726

Query: 460 VGVPGDPGEAGPIGPKGYRGDEGP------PGSEGARGAPGPAGPPGDPGLMGERGEDGP 513
            G+PG+ G AG  GPKG RGD GP      PG +G RG  GP GPPG  G  G++GE GP
Sbjct: 727 QGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGP 786

Query: 514 AG----------------------NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGE 551
           +G                       G  G PG  G PG +G PG  G KG  G  G  G 
Sbjct: 787 SGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGP 846

Query: 552 AGDPGDDNNDIAPRGVKGAKGYRGPE------------GPQGPPGHQGPPGP 591
           AG PG   N  AP G KGA+G  GP             GP GP G+ GPPGP
Sbjct: 847 AGPPGPIGNVGAP-GAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGP 897



 Score =  294 bits (752), Expect = 3e-79
 Identities = 175/400 (43%), Positives = 193/400 (48%), Gaps = 66/400 (16%)

Query: 255  ARGPPGLRGDP------GFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRG 308
            ARG PG RG+P      GF G  G  G PG KGE GD G  GD GP G  G  G  G  G
Sbjct: 795  ARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIG 854

Query: 309  EKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYP------GLPGCKGSPGFDGIQGP----- 357
              G+ G KG +G  G  G  G  G  G +G P      G PG  G  G +G +GP     
Sbjct: 855  NVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETG 914

Query: 358  ----PGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEG 413
                PG  G PG  G  GEKG PGADG AG PG+ GP G  GQ G  G PG++GE G  G
Sbjct: 915  PAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPG 974

Query: 414  NPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIG 473
             PGP G PG++G  G  G RG P   GP G PG AGP G+ GREG  G  G PG  G  G
Sbjct: 975  LPGPSGEPGKQGPSGASGERGPP---GPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPG 1031

Query: 474  PKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG------------------ 515
             KG RG+ GP G  GA GAPG  GP G  G  G+RGE GPAG                  
Sbjct: 1032 AKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQG 1091

Query: 516  -------------------NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPG 556
                                G  G  G PG PG+ G  G +G  G  G +G  G AG PG
Sbjct: 1092 PRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPG 1151

Query: 557  DDN-----NDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
             D        I P G +G  G  GP GP GPPG  GPPGP
Sbjct: 1152 KDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGP 1191



 Score =  293 bits (751), Expect = 4e-79
 Identities = 175/403 (43%), Positives = 200/403 (49%), Gaps = 69/403 (17%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGE---------AGDPGRPGDLGPVGYQGM---KGEK 304
           G PG  G  G  GERG+PG PG  G          AG PG  G  GP G+ G    KGE 
Sbjct: 296 GAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEA 355

Query: 305 GSRGEKGSRGPKGYKGEKGK---------RGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQ 355
           G +G +GS GP+G +GE G           G  G DG  G  G  G PG  G+PGF G +
Sbjct: 356 GPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGAR 415

Query: 356 GPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP 415
           GP GP+G  G  G KG  GEPGA G  G  G+ G  G  G  G PGP GE+G+ G  G P
Sbjct: 416 GPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEP 475

Query: 416 GP---DGAPGERGGPGER---------------GPRGTPGTRGPRGDPGEAGPQGDQGRE 457
           GP    G PGERGGPG R               G RG+PG  GP+G PGEAG  G+ G  
Sbjct: 476 GPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLP 535

Query: 458 GPVGVPGDP------GEAGPIGPKGYRGDEGPPGSEGARGA------PGPAGPPGDPGLM 505
           G  G+ G P      G+ GP GP G  G  GPPG  GARG       PGP G  G+PG  
Sbjct: 536 GAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA 595

Query: 506 GERGEDGPAG----------NGTEGFPGFPGYPGNRGAPGINGTKGY---PGLKGDEGEA 552
           GERG  GP G           G +G PG  G  G RG  G  G+ G+   PG  G  GEA
Sbjct: 596 GERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEA 655

Query: 553 GDPGD-----DNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           G PG+     D     P G +G +G+ G  G QGPPG  GP G
Sbjct: 656 GKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRG 698



 Score =  293 bits (750), Expect = 6e-79
 Identities = 172/375 (45%), Positives = 196/375 (52%), Gaps = 51/375 (13%)

Query: 253 QPARGPPGLRGDPGFE---GERGKPGLP---GEKGEAGDPGRPGDLGPVGYQGMKGEKGS 306
           Q  +GPPG  G+PG     G RG PG P   G+ GEAG PGRPG+ GP G QG +G  G+
Sbjct: 199 QGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGT 258

Query: 307 RGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366
            G  G +G +G+ G  G +G  G  G KGE   PG PG  G+PG  G +G PG +G PGA
Sbjct: 259 AGLPGMKGHRGFSGLDGAKGDAGPAGPKGE---PGSPGENGAPGQMGPRGLPGERGRPGA 315

Query: 367 FGLKGEKGEPGADGEAGRPGSSGPSGDEGQP------------------------GEPGP 402
            G  G +G  GA G AG PG +GP+G  G P                        GEPGP
Sbjct: 316 PGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGP 375

Query: 403 PGEKGEAGDEGNPGPDGAPGER---GGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGP 459
           PG  G AG  GNPG DG PG +   G PG  G  G PG RGP G  G  GP G +G  G 
Sbjct: 376 PGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGE 435

Query: 460 VGVP---GDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN 516
            G P   GD G  G  GP G +G  GP G EG RGA G  GP G PG  GERG     G 
Sbjct: 436 PGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERG-----GP 490

Query: 517 GTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGP 576
           G+ GFPG  G  G +G  G  G+ G  G KG  GEAG PG+        G+ GAKG  G 
Sbjct: 491 GSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGE-------AGLPGAKGLTGS 543

Query: 577 EGPQGPPGHQGPPGP 591
            G  GP G  GPPGP
Sbjct: 544 PGSPGPDGKTGPPGP 558



 Score =  292 bits (748), Expect = 1e-78
 Identities = 172/387 (44%), Positives = 199/387 (51%), Gaps = 54/387 (13%)

Query: 255  ARGPPGLRGDPGFEGERG---------------KPGLPGEKGEAGDPGRPGDLGPVGYQG 299
            A GP G RG+ GF GERG                PG  G KG+AG PG PG  G  G QG
Sbjct: 669  APGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQG 728

Query: 300  MKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPG 359
            M GE+G+ G  G +G +G  G KG  G  G DGV+G  G  G PG  G+PG  G  GP G
Sbjct: 729  MPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSG 788

Query: 360  PKGDPGAFGLKGEKGEPGADGEAG---------RPGSSGPSGDEGQPGEPGPPGEKGEAG 410
            P G  GA G  G++GEPG  G AG         +PG+ G  GD G  G+ GPPG  G AG
Sbjct: 789  PAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAG 848

Query: 411  DEGNPGPDGAPGERG-----GP----------GERGPRGTPGTRGPRGDPGEAGPQGDQG 455
              G  G  GAPG +G     GP          G  GP G  G  GP G PG AG +G +G
Sbjct: 849  PPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKG 908

Query: 456  REGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDG-PA 514
              G  G  G PGE GP GP G  G++G PG++G  GAP   G PG  G+ G+RG  G P 
Sbjct: 909  PRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAP---GTPGPQGIAGQRGVVGLPG 965

Query: 515  GNGTEGFPGFP---GYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAP------- 564
              G  GFPG P   G PG +G  G +G +G PG  G  G AG PG+   + AP       
Sbjct: 966  QRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPG 1025

Query: 565  -RGVKGAKGYRGPEGPQGPPGHQGPPG 590
              G  GAKG RG  GP GPPG  G PG
Sbjct: 1026 RDGSPGAKGDRGETGPAGPPGAPGAPG 1052



 Score =  291 bits (744), Expect = 3e-78
 Identities = 167/369 (45%), Positives = 190/369 (51%), Gaps = 41/369 (11%)

Query: 257  GPPGLRGDPGFEGERGKPG---------LPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSR 307
            GPPG  G PG +GE G  G          PG++GE G PG  G  GP G  G  G KG  
Sbjct: 770  GPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEP 829

Query: 308  GEKGSRG------PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361
            G+ G++G      P G  G  G  G  G  G KG  G  G PG  G PG  G  GPPGP 
Sbjct: 830  GDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPS 889

Query: 362  GD------PGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP 415
            G+      PG  G +G KG  G  G AGRPG  GP G  G  GE G PG  G AG  G P
Sbjct: 890  GNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTP 949

Query: 416  GPDGAPGERGG---PGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPI 472
            GP G  G+RG    PG+RG RG PG  GP G+PG+ GP G  G  GP G  G PG AGP 
Sbjct: 950  GPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPP 1009

Query: 473  GPKGYRGD---------EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFP 522
            G  G  G          +G PG++G RG  GPAGPPG PG  G  G  GPAG +G  G  
Sbjct: 1010 GESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGET 1069

Query: 523  GFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGP 582
            G  G  G  G  G  G  G  G +GD+GE G+ GD       RG+KG +G+ G +GP GP
Sbjct: 1070 GPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGD-------RGIKGHRGFSGLQGPPGP 1122

Query: 583  PGHQGPPGP 591
            PG  G  GP
Sbjct: 1123 PGSPGEQGP 1131



 Score =  290 bits (741), Expect = 6e-78
 Identities = 160/341 (46%), Positives = 182/341 (53%), Gaps = 12/341 (3%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
           GP G++G PG  GE GK G  GE G  G PG PG+ G  G +G  G  G  G KG  G +
Sbjct: 452 GPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGER 511

Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376
           G  G  G +G  G  G  GE G PG  G  GSPG  G  G  GP G  G  G  G  G P
Sbjct: 512 GSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPP 571

Query: 377 GADGEAGRPGSSGPSGDEGQPGE------PGPPGEKGEAGDEGNPGPDGAPGERGGPGER 430
           GA G+AG  G  GP G  G+PG+      PGPPG  G AG +G  G  G PG  G  GER
Sbjct: 572 GARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGER 631

Query: 431 GPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGAR 490
           G +G  G+ G +G PG AGP G+ G+ G  GVPGD    G  GP G RG+ G PG  G +
Sbjct: 632 GEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGD---LGAPGPSGARGERGFPGERGVQ 688

Query: 491 GAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEG 550
           G PGPAGP G  G  G  G  G A  G  G PG  G PG +G PG  G  G PG KGD G
Sbjct: 689 GPPGPAGPRGANGAPGNDGAKGDA--GAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRG 746

Query: 551 EAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
           +AG  G D +     GV+G  G  GP GP G PG +G  GP
Sbjct: 747 DAGPKGADGSP-GKDGVRGLTGPIGPPGPAGAPGDKGESGP 786



 Score =  288 bits (737), Expect = 2e-77
 Identities = 166/353 (47%), Positives = 187/353 (52%), Gaps = 20/353 (5%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            GP G  G PG +G RG  G  G  G AG PG  G+ GP G  G  G +G+ G++G  GP 
Sbjct: 749  GPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPP 808

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD---PGAFGLKGEK 373
            G  G  G  G DG  G KGE G  G  G  G PG  G  GPPGP G+   PGA G +G  
Sbjct: 809  GPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSA 868

Query: 374  GEPGADG---EAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGER 430
            G PGA G    AGR G  GPSG+ G PG PGP G++G  G  G  GP G PGE G PG  
Sbjct: 869  GPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPP 928

Query: 431  GP---RGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487
            GP   +G+PG  GP G PG  GPQG  G+ G VG+PG  GE G  G  G  G+ G  G  
Sbjct: 929  GPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPS 988

Query: 488  GARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNR---------GAPGIN 537
            GA G  GP GP G PGL G  GE G  G  G EG PG  G PG +         G PG  
Sbjct: 989  GASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAP 1048

Query: 538  GTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
            G  G PG  G  G++GD G +     P G  G  G RGP GPQGP G +G  G
Sbjct: 1049 GAPGAPGPVGPAGKSGDRG-ETGPAGPAGPVGPVGARGPAGPQGPRGDKGETG 1100



 Score =  285 bits (730), Expect = 1e-76
 Identities = 163/369 (44%), Positives = 184/369 (49%), Gaps = 35/369 (9%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP- 315
           GP G +G+PG  GE G PG  G +G  G+ GRPG  GP G +G  G  G+ G  G  GP 
Sbjct: 281 GPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPA 340

Query: 316 -----------KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDP 364
                      KG  G +G RG +G  GV+GE G PG  G  G  G  G  G PG KG  
Sbjct: 341 GPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGAN 400

Query: 365 GAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPG-- 422
           GA G+ G  G PGA G +G  G  GP G +G  GEPG PG KG+ G +G PGP G  G  
Sbjct: 401 GAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPP 460

Query: 423 -------ERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475
                  +RG  GE GP G PG  G RG PG  G  G  G  GP G  G+ G  GP GPK
Sbjct: 461 GPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPK 520

Query: 476 GYRGDEGPPGSEGARGA---------PGPAGPPGDPGLMGERGEDGPAG----NGTEGFP 522
           G  G+ G PG  G  GA         PGP G  G PG  G+ G  GP G     G  G  
Sbjct: 521 GSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVM 580

Query: 523 GFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGP 582
           GFPG  G  G PG  G +G PG  G  G AG  G+      P G  G  G RG +GP G 
Sbjct: 581 GFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQ-GPPGPAGPAGERGEQGPAGS 639

Query: 583 PGHQGPPGP 591
           PG QG PGP
Sbjct: 640 PGFQGLPGP 648



 Score =  285 bits (728), Expect = 2e-76
 Identities = 164/360 (45%), Positives = 186/360 (51%), Gaps = 33/360 (9%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
           GP G RG  G +G RG+PG PG  G AG  G PG  G  G +G  G  G  G  G  G +
Sbjct: 356 GPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGAR 415

Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPG---CKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373
           G  G +G  G  G  G  GE G PG  G    KG PG  G+QGPPGP G+ G  G +GE 
Sbjct: 416 GPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEP 475

Query: 374 GE---PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGE---AGDEGNPGPDGAPGERGGP 427
           G    PG  GE G PGS G  G +G  G  GP GE+G    AG +G+PG  G PGE G P
Sbjct: 476 GPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLP 535

Query: 428 GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487
           G +G  G+PG+ GP G  G  GP G  GR GP G PG  G+AG +G  G +G  G PG  
Sbjct: 536 GAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA 595

Query: 488 GARGAPGP---------------AGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRG 532
           G RG PGP                GPPG  G  GERGE GPAG+     PGF G PG  G
Sbjct: 596 GERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGS-----PGFQGLPGPAG 650

Query: 533 APGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592
            PG  G  G  G+ GD G  G  G        RG  G +G +GP GP GP G  G PG D
Sbjct: 651 PPGEAGKPGEQGVPGDLGAPGPSGARGE----RGFPGERGVQGPPGPAGPRGANGAPGND 706



 Score =  282 bits (722), Expect = 1e-75
 Identities = 166/373 (44%), Positives = 183/373 (49%), Gaps = 45/373 (12%)

Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314
           A+G  G  G PG +G+ G PG  G+ G  G PG PG  G  G  G  G KG+ GE G  G
Sbjct: 537 AKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAG 596

Query: 315 PKGYKGEKGKRGIDGVDGVKGEMGYP---------GLPGCKGSPGFDGIQGPPGP----- 360
            +G  G  G  G  G DG  G  G P         G  G  GSPGF G+ GP GP     
Sbjct: 597 ERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAG 656

Query: 361 -------KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEG 413
                   GD GA G  G +GE G  GE G  G  GP+G  G  G PG  G KG+AG  G
Sbjct: 657 KPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPG 716

Query: 414 NPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGRE------------GPVG 461
            PG  GAPG +G PGERG  G PG +G RGD G  G  G  G++            GP G
Sbjct: 717 APGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAG 776

Query: 462 VPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGP---AGPPGDPGLMGERGEDGPAGNGT 518
            PGD GE+GP GP G  G  G PG  G  G PGP   AGPPG  G  G +GE G A  G 
Sbjct: 777 APGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDA--GA 834

Query: 519 EGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEG 578
           +G  G PG  G  G PG  G  G PG KG  G AG PG         G  GA G  GP G
Sbjct: 835 KGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPG-------ATGFPGAAGRVGPPG 887

Query: 579 PQGPPGHQGPPGP 591
           P G  G  GPPGP
Sbjct: 888 PSGNAGPPGPPGP 900



 Score =  280 bits (717), Expect = 4e-75
 Identities = 170/381 (44%), Positives = 193/381 (50%), Gaps = 46/381 (12%)

Query: 257 GPPGLRGDPGFEGERGKPGL----------------------PGEKGEAGD---PGRPGD 291
           G PGL G PG  G  G PGL                      PG  G +G    PG PG 
Sbjct: 136 GQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGA 195

Query: 292 LGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGF 351
            GP G+QG  GE G  G  G  GP+G  G  GK G DG  G  G  G  G PG +G+ G 
Sbjct: 196 PGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGL 255

Query: 352 DGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD 411
            G  G PG KG  G  GL G KG+ G  G  G PGS G +G  GQ G  G PGE+G  G 
Sbjct: 256 PGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGA 315

Query: 412 EGNPGP---DGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGV---PGD 465
            G  G    DGA G  G PG  GP G PG  G  G  GEAGPQG +G EGP GV   PG 
Sbjct: 316 PGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGP 375

Query: 466 PGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEGF 521
           PG AG  GP G  G +G PG++GA GAPG AG PG PG  G  G  GP G     G  G 
Sbjct: 376 PGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGE 435

Query: 522 PGFPGYPGNRGA---PGINGTKGYPGLKGDEGEAGDPGDDNNDIAP-----RGVKGAKGY 573
           PG PG  G+ GA   PG  G +G PG  G+EG+ G  G+      P     RG  G++G+
Sbjct: 436 PGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGF 495

Query: 574 RGPE---GPQGPPGHQGPPGP 591
            G +   GP+GP G +G PGP
Sbjct: 496 PGADGVAGPKGPAGERGSPGP 516



 Score =  275 bits (702), Expect = 2e-73
 Identities = 164/370 (44%), Positives = 180/370 (48%), Gaps = 39/370 (10%)

Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312
           Q   G  G +GD G  G RG  G PG  G  G PG PG  GP G  G  G  G+   + S
Sbjct: 105 QETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLS 164

Query: 313 RG----------PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKG 362
            G            G  G  G RG+ G  G  G  G+ G PG  G PG  G  GP GP G
Sbjct: 165 YGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPG 224

Query: 363 DPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGE---------KGEAGDEG 413
            PG  G  GE G+PG  GE G PG  G  G  G  G PG  G          KG+AG  G
Sbjct: 225 PPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAG 284

Query: 414 NPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGP-- 471
             G  G+PGE G PG+ GPRG PG RG  G PG AG +G+ G  G  G PG  G AGP  
Sbjct: 285 PKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPG 344

Query: 472 ----IGPKGYRGDEGPPGSE---GARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEG 520
               +G KG  G +GP GSE   G RG PGP GP G  G  G  G DG  G    NG  G
Sbjct: 345 FPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPG 404

Query: 521 FPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQ 580
             G PG+PG RG  G  G  G PG KG+ GE G PG        +G  GAKG  GP G Q
Sbjct: 405 IAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGS-------KGDTGAKGEPGPVGVQ 457

Query: 581 GPPGHQGPPG 590
           GPPG  G  G
Sbjct: 458 GPPGPAGEEG 467



 Score =  256 bits (654), Expect = 8e-68
 Identities = 158/377 (41%), Positives = 182/377 (48%), Gaps = 58/377 (15%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            GP G  G PG  G  GK G  G +GE G  GRPG++GP G  G  GEKGS G  G  G  
Sbjct: 887  GPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAP 946

Query: 317  GYKGEKG---KRGIDGVDGVKGEMGYPGLPGCKGSPG------FDGIQGPPGPKGDPGAF 367
            G  G +G   +RG+ G+ G +GE G+PGLPG  G PG        G +GPPGP G PG  
Sbjct: 947  GTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLA 1006

Query: 368  GLKGEKGE---PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGER 424
            G  GE G    PGA+G  GR GS G  GD G+ G  GPPG  G  G  G  GP G  G+R
Sbjct: 1007 GPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDR 1066

Query: 425  GGPGERGP---------RGTPGTRGPRGDPGEAGPQGDQG---------REGPVGVPGDP 466
            G  G  GP         RG  G +GPRGD GE G QGD+G          +GP G PG P
Sbjct: 1067 GETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSP 1126

Query: 467  GEAGPIGPKGYRGDEGPPGSEGA------RGAPGPAGPPGDPGLMGERGEDGPAGNGTEG 520
            GE GP G  G  G  GPPGS GA       G PGP GPPG  G  G+ G  GP       
Sbjct: 1127 GEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGP------- 1179

Query: 521  FPGFPGYPGNRGAPGINGTKGY----PGLKGDEGEAGDPGDDNNDIAPRGV--------- 567
             PG PG PG  G P       +    P  K  +G      DD N +  R +         
Sbjct: 1180 -PGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRYYRADDANVVRDRDLEVDTTLKSL 1238

Query: 568  -KGAKGYRGPEGPQGPP 583
             +  +  R PEG +  P
Sbjct: 1239 SQQIENIRSPEGSRKNP 1255



 Score =  205 bits (522), Expect = 2e-52
 Identities = 122/287 (42%), Positives = 135/287 (47%), Gaps = 36/287 (12%)

Query: 340 PGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE 399
           P  P    SP      G  GPKGD G  G +G  G PG DG  G+PG  GP G  G PG 
Sbjct: 93  PVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGP 152

Query: 400 PG----------------------PPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPG 437
           PG                       PG  G +G  G PGP GAPG +G  G  G  G PG
Sbjct: 153 PGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPG 212

Query: 438 TRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYR------------GDEGPPG 485
             GP G  G  GP G  G +G  G PG PGE GP GP+G R            G  G  G
Sbjct: 213 ASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSG 272

Query: 486 SEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGTKGYPG 544
            +GA+G  GPAGP G+PG  GE G  G  G  G  G  G PG PG  GA G +G  G  G
Sbjct: 273 LDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAG 332

Query: 545 LKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
             G  G AG PG     +  +G  G +G RG EGPQG  G  GPPGP
Sbjct: 333 PPGPTGPAGPPGFP-GAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGP 378



 Score =  132 bits (332), Expect = 2e-30
 Identities = 84/199 (42%), Positives = 98/199 (49%), Gaps = 15/199 (7%)

Query: 403 PGEKGEAGDEGNPGPDGA--PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPV 460
           PG +   G+     PDG+  P ++   G  GP+G  G RGPRG    AGP G  G  G  
Sbjct: 82  PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGP---AGPPGRDGIPGQP 138

Query: 461 GVPGDPGEAGPIGPKGYRGDEGPP-------GSEGARGAPGPAGPPGDPGLMGERGEDGP 513
           G+PG PG  GP GP G  G+  P         S G    PGP GP G  GL G  G  GP
Sbjct: 139 GLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGP 198

Query: 514 AGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573
              G +G PG PG PG  G  G  G  G PG  GD+GEAG PG    +  P G +GA+G 
Sbjct: 199 --QGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPG-ERGPPGPQGARGL 255

Query: 574 RGPEGPQGPPGHQGPPGPD 592
            G  G  G  GH+G  G D
Sbjct: 256 PGTAGLPGMKGHRGFSGLD 274



 Score = 92.4 bits (228), Expect = 2e-18
 Identities = 58/158 (36%), Positives = 69/158 (43%), Gaps = 43/158 (27%)

Query: 251  ECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310
            E  PA GPPG  G PG  G  G  G  G++GE G  G  G +GPVG +G  G +G RG+K
Sbjct: 1038 ETGPA-GPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDK 1096

Query: 311  GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGL---------------PGCKGSPGFDGIQ 355
            G  G +G +G KG RG  G+ G  G  G PG                PG  G+PG DG+ 
Sbjct: 1097 GETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLN 1156

Query: 356  G---------------------------PPGPKGDPGA 366
            G                           PPGP G P A
Sbjct: 1157 GLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSA 1194


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score =  305 bits (782), Expect = 1e-82
 Identities = 169/357 (47%), Positives = 192/357 (53%), Gaps = 21/357 (5%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG---S 312
            +G PG RG  G  G RG PG  GE G  G  G  G  GP G  G+KGE G  G+KG   S
Sbjct: 815  KGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGS 874

Query: 313  RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372
             GP+G  G  G  G +GV G+KG  G  G PG  G PG  G  GPPGP G PG  G  GE
Sbjct: 875  PGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGE 934

Query: 373  KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGP 432
             G+ G  G  G PGS G  GD G  G PG PG+KG+ G++G PGPDG PG  G  G+RG 
Sbjct: 935  PGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGI 994

Query: 433  RGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGA 492
             G PG RG RG PG  GP G  G+ GP G  GD G  GP+GP G  G  G PG EG  G 
Sbjct: 995  VGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGN 1054

Query: 493  PGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFP------------GYPGNR---GAPGI 536
             G  G  G  G  G+RG+ GPAG  G++G PG P            G PG+R   G PG 
Sbjct: 1055 DGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGR 1114

Query: 537  NGTKGYPGLKGDEGEAGDPGD--DNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
             G +G PG +G  G+ GD GD  D      RG  G +G  GP GP G  G  G PGP
Sbjct: 1115 AGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGP 1171



 Score =  298 bits (762), Expect = 2e-80
 Identities = 173/393 (44%), Positives = 204/393 (51%), Gaps = 59/393 (15%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
           G  GL G  G +GERG  G  G KG  GDPGRPG+ G  G +G+ G  G +G +G  GP 
Sbjct: 531 GSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPL 590

Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGS---------------------PGFDGIQ 355
           G  GE G+ G  G  G++G+ G  GLPG KGS                     PG DG  
Sbjct: 591 GAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEV 650

Query: 356 GPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAG----- 410
           GP GP G PG  G +GE+G PG  G  G PG  GP G+ G+PG+ G PG+ G  G     
Sbjct: 651 GPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPR 710

Query: 411 -DEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEA 469
            + GNPG  G PG  G PGE+G  G  G  GP+G PG +G  GD G  G  G+PG+ G A
Sbjct: 711 GERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIA 770

Query: 470 GPIGPKGYRGD------EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-------- 515
           G  GPKG RG       EG  G++GARG PGP GPPG  G  GE+GE GP G        
Sbjct: 771 GTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSR 830

Query: 516 --------NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGD------EGEAGDPGDDNND 561
                   NG  G  GF G  G  G PG+ G  G PG KGD      +G AG PG    +
Sbjct: 831 GNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPN 890

Query: 562 IAPRGVKGAKGYRGPEGPQGPP---GHQGPPGP 591
             P G+KG +G +GP G  G P   G  GPPGP
Sbjct: 891 GVP-GLKGGRGTQGPPGATGFPGSAGRVGPPGP 922



 Score =  295 bits (754), Expect = 2e-79
 Identities = 161/348 (46%), Positives = 190/348 (54%), Gaps = 12/348 (3%)

Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314
           ARG PG  G PG +G RG  GL G KGE G PG  G+ GP G  G  G  G RG  G RG
Sbjct: 286 ARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERG 345

Query: 315 PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKG 374
             G +G  G+RG  G+ G  G MG  G+PG  G PG  G++G  GP G  G  G +G++G
Sbjct: 346 RLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRG 405

Query: 375 EPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRG 434
           E G  G  G PG  G  G +G PG  GP G  G +G  G+ GP G+PG +G  G +G RG
Sbjct: 406 ETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRG 465

Query: 435 TPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPG 494
            PG  G  G  GEAGP+G+ G  G  G  G PGE G  GP+G  G  GPPG  G RGAPG
Sbjct: 466 QPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPG 525

Query: 495 PAGPPGD---PGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEG 550
             G PG    PG  G +GE GP G +G +G  G PG PG  G PG  G  G PG++G EG
Sbjct: 526 NRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEG 585

Query: 551 EAGD---PGDDN-----NDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           + G    PG+D        I  RG  G+ G  GP+G  G PG  G  G
Sbjct: 586 KLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAG 633



 Score =  292 bits (747), Expect = 1e-78
 Identities = 179/412 (43%), Positives = 196/412 (47%), Gaps = 83/412 (20%)

Query: 257  GPPGLRGD---------PGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSR 307
            GPPGL G+          GF+G  G PG PGE G+ GD G PGD G VG  G +GE+G+ 
Sbjct: 657  GPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNP 716

Query: 308  GEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDG------IQGPPGPK 361
            GE+G  G  G  GEKG  G  G DG KG  G  G PG  G PG  G      I G PGPK
Sbjct: 717  GERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPK 776

Query: 362  GDPGAFGLKG---------------------------EKGEPGADGEAGRPGS------- 387
            GD G  G KG                           EKGEPG  G  G PGS       
Sbjct: 777  GDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSR 836

Query: 388  -----------SGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436
                       +GP G +GQPG  G PGE G+ GD G+PGP G  G    PG  GP G P
Sbjct: 837  GENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGS---PGPHGPNGVP 893

Query: 437  GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPG------SEGAR 490
            G +G RG  G  G  G  G  G VG PG  G  GP GP G  G EGPPG      S G  
Sbjct: 894  GLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRV 953

Query: 491  GAPGPAGPPGDPGLMGERGED---------GPAG-NGTEGFPGFPGYPGNRGAPGINGTK 540
            G  GPAGPPG PG  G+ GED         GPAG  G  G  G PG  G RG PG+ G  
Sbjct: 954  GDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPA 1013

Query: 541  GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592
            G PG  G  G  GD G       P G  G+ G  G  GP+GP G+ G PG D
Sbjct: 1014 GTPGKVGPTGATGDKGPP----GPVGPPGSNGPVGEPGPEGPAGNDGTPGRD 1061



 Score =  291 bits (744), Expect = 3e-78
 Identities = 159/348 (45%), Positives = 191/348 (54%), Gaps = 20/348 (5%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
           GP G  G  G +G  G PG  G++G  GDPG  G  GPVG +G  G +G  G  G  GPK
Sbjct: 480 GPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPK 539

Query: 317 GYKGEKGKRGIDGVDGVKGE---MGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373
           G +GE+G  G  G  G +G+    G PGLPG +G  G  G+QGP G  G  GA G  G  
Sbjct: 540 GAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRP 599

Query: 374 GEPGADGEAGRPGS---SGPSGDEGQPGEPGP------PGEKGEAGDEGNPGPDGAPGER 424
           G PG+ G  G+PGS    GP G  G PG+PG       PG++G  G +G  GP G  G  
Sbjct: 600 GPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPP 659

Query: 425 GGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPP 484
           G  GERG +G PG  G +G PG  GP G+ G+ G  GVPGDPG  GP+GP+G R      
Sbjct: 660 GLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGER------ 713

Query: 485 GSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTKGYP 543
           G+ G RG PG  G PG+ G+ G  G DGP G+ G  G PG  G PG +G PG  G  G P
Sbjct: 714 GNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTP 773

Query: 544 GLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
           G KGD G  G+ G +       G +G  G  GP GP GP G +G PGP
Sbjct: 774 GPKGDRGGIGEKGAEGT-AGNDGARGLPGPLGPPGPAGPTGEKGEPGP 820



 Score =  290 bits (742), Expect = 5e-78
 Identities = 167/357 (46%), Positives = 189/357 (52%), Gaps = 29/357 (8%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPG------DLGPVGYQGMKGEKGSRGEK 310
            GP GL G PG  G  G PGL G +G  G PG  G       +GP G  G  G  G  GE 
Sbjct: 876  GPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEP 935

Query: 311  GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGI---QGPPGPKGDPGAF 367
            G  GP G +G+ G  G  G    +G  G PG PG KG PG DG     GPPGP G  G  
Sbjct: 936  GKEGPPGLRGDPGSHGRVGD---RGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQR 992

Query: 368  GL------KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAP 421
            G+      +GE+G PG  G AG PG  GP+G  G  G PGP G  G  G  G PGP+G  
Sbjct: 993  GIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPA 1052

Query: 422  GERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE 481
            G  G PG     G  G RG RGDPG AG  G QG  G  G  G PG+AG  G  G RG  
Sbjct: 1053 GNDGTPGR---DGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPI 1109

Query: 482  GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN----GTEGFPGFPGYPGNRGA---P 534
            GPPG  G RG PGP GP GD G  G+RG+ G  G+    G +G PG PG  G +G+   P
Sbjct: 1110 GPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIP 1169

Query: 535  GINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
            G  G +G PG  G  G+ G+PG     I P GV+G+ G  GPEGP G PG  GPPGP
Sbjct: 1170 GPFGPRGPPGPVGPSGKEGNPG-PLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGP 1225



 Score =  289 bits (739), Expect = 1e-77
 Identities = 161/362 (44%), Positives = 194/362 (53%), Gaps = 32/362 (8%)

Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQG---------MKGEKG 305
           A GP G RG PG  G  G  G PG++G  G PG+PG +GP+G  G         MKGE G
Sbjct: 331 AMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAG 390

Query: 306 SRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPG 365
             G +G  GP+G +GE G  G  G  G+ G +G  G PG KG  G  G  GPPG  G PG
Sbjct: 391 PTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPG 450

Query: 366 AFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGP---------PGEKGEAGDEGNPG 416
           + G +G  G  G  G+ G PG  G  G+ G  GEPGP         PGE+G+ G  G+PG
Sbjct: 451 SPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPG 510

Query: 417 ---PDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIG 473
              P G  GERG PG RG  G+ G  GP+G  GE GP G  G +G  G PG PGE G  G
Sbjct: 511 TVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPG 570

Query: 474 PKGYRGD---EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPG 529
            +G  G+   +GP G  G  GAPG  G PG PG +G RG+ G  G  G +G  G PG PG
Sbjct: 571 ARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPG 630

Query: 530 NRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPP 589
             G  G+ G +G PG  G+ G +G  G       P G+ G +G +GP GP G  G  GPP
Sbjct: 631 EAGNAGVPGQRGAPGKDGEVGPSGPVG-------PPGLAGERGEQGPPGPTGFQGLPGPP 683

Query: 590 GP 591
           GP
Sbjct: 684 GP 685



 Score =  289 bits (739), Expect = 1e-77
 Identities = 167/378 (44%), Positives = 193/378 (51%), Gaps = 42/378 (11%)

Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEA------GDPGRPGDLGPVGYQGMKGEKGSRGE 309
           RG PG  G PG +G  G PG PGE G A      G PG+ G++GP G  G  G  G RGE
Sbjct: 608 RGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGE 667

Query: 310 KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGL 369
           +G  GP G++G  G  G  G  G  G+ G PG PG  G  G  G +G PG +G+PG  GL
Sbjct: 668 QGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGL 727

Query: 370 KGEK---------GEPGADGEAGRPGSSGPSGDEGQPGE------PGPPGEKGEAGDE-- 412
            GEK         G  G+ G +G PG +GP G +G PGE      PGP G++G  G++  
Sbjct: 728 PGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGA 787

Query: 413 ----------------GNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGR 456
                           G PGP G  GE+G PG RG  G PG+RG  G  GE GP G  G 
Sbjct: 788 EGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGF 847

Query: 457 EGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG- 515
            GP G  G PG  G  G  G +GD G PG +G  G+PGP GP G PGL G RG  GP G 
Sbjct: 848 AGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGA 907

Query: 516 NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN--NDIAPRGVKGAKGY 573
            G  G  G  G PG  GAPG  G  G PG +G  G  GDPG      D  P G  G  G 
Sbjct: 908 TGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGD 967

Query: 574 RGPEGPQGPPGHQGPPGP 591
           +G  G  G PG  GPPGP
Sbjct: 968 KGDPGEDGQPGPDGPPGP 985



 Score =  287 bits (734), Expect = 4e-77
 Identities = 159/349 (45%), Positives = 182/349 (52%), Gaps = 18/349 (5%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
           G PG  G  G  G+ G  GLPG KG +GDPG+PG+ G  G  G +G  G  GE G  GP 
Sbjct: 597 GRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPV 656

Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376
           G  G  G+RG  G  G  G  G PG PG  G  G  G QG PG   DPGA G  G +GE 
Sbjct: 657 GPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPG---DPGAVGPLGPRGER 713

Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436
           G  GE G PG +G  G++G  G  GP G KG  G  G PG  G PG +G PGERG  GTP
Sbjct: 714 GNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTP 773

Query: 437 GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE------GPPGSEGAR 490
           G +G RG  GE G +G  G +G  G+PG  G  GP GP G +G+       GPPGS G  
Sbjct: 774 GPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNP 833

Query: 491 GAPGPAGPPGDPGLMGERGEDG-------PAGNGTEGFPGFPGYPGNRGAPGINGTKGYP 543
           G+ G  GP G  G  G +G DG       P   G +G  G PG  G  G+PG +G  G P
Sbjct: 834 GSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVP 893

Query: 544 GLKGDEGEAGDPGDDN--NDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           GLKG  G  G PG           G  G  G  GP GP G PG +GPPG
Sbjct: 894 GLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPG 942



 Score =  285 bits (728), Expect = 2e-76
 Identities = 163/355 (45%), Positives = 189/355 (53%), Gaps = 24/355 (6%)

Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314
           +RGP G  G PG +GE G+ G PGE G AG PG  G  G  G  G+KG +G +G +G +G
Sbjct: 253 SRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKG 312

Query: 315 PKGYKGEKGKRGIDGVDGVKGEMGYPGLPG---------CKGSPGFDGIQGPPGPKGDPG 365
             G  G KG+ G  G  G  G +G  G+PG           G  G  G+ G PGP G  G
Sbjct: 313 EVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLG 372

Query: 366 AFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERG 425
             G  G  G PG  GEAG  G+ GP G +GQ GE GPPG  G  G  G  G DG PG +G
Sbjct: 373 IPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKG 432

Query: 426 GPGERGPRGTPGTRGPRGDPG---EAGPQGDQGREGPVGVPGDPGEAGP---IGPKGYRG 479
             G  G  G PG+ GP G PG     GPQG +G+ G  GVPG  GEAGP    GP G +G
Sbjct: 433 PTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQG 492

Query: 480 DEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGT 539
             GPPG EG RG  G  G  G PG +GERG       G  GFPG  G PG +GA G  G 
Sbjct: 493 PIGPPGEEGKRGPRGDPGTVGPPGPVGERG-----APGNRGFPGSDGLPGPKGAQGERGP 547

Query: 540 KGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPE---GPQGPPGHQGPPGP 591
            G  G KG +G+ G PG+     A RG+ G  G +GPE   GP G PG  G PGP
Sbjct: 548 VGSSGPKGSQGDPGRPGEPGLPGA-RGLTGNPGVQGPEGKLGPLGAPGEDGRPGP 601



 Score =  281 bits (718), Expect = 3e-75
 Identities = 155/346 (44%), Positives = 185/346 (53%), Gaps = 17/346 (4%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGD---LGPVGYQGMKGEKGSRGEKGSR 313
           GP G  G  G  G+ G PG+PG KGEAG  G PG     GP+G  G +G++G RG+ G+ 
Sbjct: 453 GPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTV 512

Query: 314 GPKGYKGEKG---KRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370
           GP G  GE+G    RG  G DG+ G  G  G  G  GS G  G QG PG  G+PG  G +
Sbjct: 513 GPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGAR 572

Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGER 430
           G  G PG  G  G+ G  G  G++G+PG PG  G +G+ G  G PGP G+ G+ G PGE 
Sbjct: 573 GLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEA 632

Query: 431 GPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGAR 490
           G  G PG RG  G  GE GP G  G   P G+ G+ GE GP GP G++G  GPPG  G  
Sbjct: 633 GNAGVPGQRGAPGKDGEVGPSGPVG---PPGLAGERGEQGPPGPTGFQGLPGPPGPPGEG 689

Query: 491 GAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDE 549
           G PG  G PGDPG +G  G  G  GN G  G PG  G PG +G  G +G  G  G  G  
Sbjct: 690 GKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPS 749

Query: 550 GEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPDECE 595
           G  GD G       P G++G  G RG  G  GP G +G  G    E
Sbjct: 750 GTPGDTG-------PPGLQGMPGERGIAGTPGPKGDRGGIGEKGAE 788



 Score =  279 bits (714), Expect = 8e-75
 Identities = 166/370 (44%), Positives = 187/370 (50%), Gaps = 42/370 (11%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
           GP G RG  G +G+RG+ G PG     G PG PG +G  G  G KG  GS G  G  G  
Sbjct: 390 GPTGARGPEGPQGQRGETGPPGP---VGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSA 446

Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGS------PGFDGIQGP---------PGPK 361
           G  G  G +G  G  G++G+ G PG+PG KG       PG  GIQGP          GP+
Sbjct: 447 GPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPR 506

Query: 362 GDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGE---KGEAGDEGNPGPD 418
           GDPG  G  G  GE GA G  G PGS G  G +G  GE GP G    KG  GD G PG  
Sbjct: 507 GDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEP 566

Query: 419 GAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYR 478
           G PG RG  G  G +G  G  GP G PGE    G  G  G +G+ G PG  G  GPKG  
Sbjct: 567 GLPGARGLTGNPGVQGPEGKLGPLGAPGE---DGRPGPPGSIGIRGQPGSMGLPGPKGSS 623

Query: 479 GDEGPPGSEGARGAP------------GPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFP 525
           GD G PG  G  G P            GP+GP G PGL GERGE GP G  G +G PG P
Sbjct: 624 GDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPP 683

Query: 526 GYPGNRGAPGINGTKGYPGL---KGDEGEAGDPGD--DNNDIAPRGVKGAKGYRGPEGPQ 580
           G PG  G PG  G  G PG     G  GE G+PG+  +       G KG  G  GP+GP+
Sbjct: 684 GPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPK 743

Query: 581 GPPGHQGPPG 590
           G PG  G PG
Sbjct: 744 GSPGPSGTPG 753



 Score =  266 bits (679), Expect = 1e-70
 Identities = 161/393 (40%), Positives = 188/393 (47%), Gaps = 57/393 (14%)

Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPG------------------------RPGD 291
           RGP G+ G+PG  G+ G PG PG     G  G                         PG 
Sbjct: 155 RGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGS 214

Query: 292 LGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGL---PGCKGS 348
           +GPVG +G +G +G +G  G  GP G  G+ G  G  G  G +G  G PG    PG  G+
Sbjct: 215 VGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGN 274

Query: 349 PGFDGIQGPPGPKGDPGAFGL------KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGP 402
           PG  G  G PG +G PGA GL      +G KG  G  GE G PGS G +G  G  G  GP
Sbjct: 275 PGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGP 334

Query: 403 PGEKGEAGDEGNPGPDGAPGERGG------PGERGPRGTPGTRGPRGDPG---------- 446
            G +G  G+ G  GP GAPG+RG       PG  GP G PG+ G  G+PG          
Sbjct: 335 LGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGA 394

Query: 447 --EAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGL 504
               GPQG +G  GP G  G PG  G IG  G  G +GP GS G  G PG AGPPG PG 
Sbjct: 395 RGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGP 454

Query: 505 MGERGEDGPAGN-GTEGFPGFPGYPGNRGAP---GINGTKGYPGLKGDEGEAGDPG--DD 558
            G  G  G  G  G  G PGF G  G +G P   GI G  G PG +G  G  GDPG    
Sbjct: 455 QGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGP 514

Query: 559 NNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
              +  RG  G +G+ G +G  GP G QG  GP
Sbjct: 515 PGPVGERGAPGNRGFPGSDGLPGPKGAQGERGP 547



 Score =  265 bits (676), Expect = 2e-70
 Identities = 156/384 (40%), Positives = 179/384 (46%), Gaps = 52/384 (13%)

Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGD----------------------- 291
           ++GP G RG  G  G RG  G+ GE G  G PG PG                        
Sbjct: 139 SQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGL 198

Query: 292 -------------LGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMG 338
                         G VG  G +G +G +G++G  GP G  GE G  G  G  G +G  G
Sbjct: 199 DEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEG 258

Query: 339 YPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPG 398
            PG PG  G PG +G  G  G  G PGA G  G  G PG  G  G  G  GP G+ G PG
Sbjct: 259 PPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPG 318

Query: 399 EPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREG 458
             G  G  G  G  G  GP G PGER   G  GP+G PG RG  G PG+ GP G  G  G
Sbjct: 319 SKGEAGPTGPMGAMGPLGPRGMPGER---GRLGPQGAPGQRGAHGMPGKPGPMGPLGIPG 375

Query: 459 PVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGT 518
             G PG+PG  G  GP G RG EGP G  G  G PGP G PG PG +G  G   P   G 
Sbjct: 376 SSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGT--PGAKGP 433

Query: 519 EGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPG--DDNNDIAPRGVKGAKGYRGP 576
            G PG  G PG+ G PG  G +G  G +G  G+ GDPG      +  P+G  G  G +GP
Sbjct: 434 TGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGP 493

Query: 577 ---------EGPQGPPGHQGPPGP 591
                     GP+G PG  GPPGP
Sbjct: 494 IGPPGEEGKRGPRGDPGTVGPPGP 517



 Score =  261 bits (667), Expect = 2e-69
 Identities = 152/344 (44%), Positives = 174/344 (50%), Gaps = 48/344 (13%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPG---RPGDLGPVGYQGMKGEKGSRGEKGSR 313
            GPPG  G PG  G  G+PG  G  G  GDPG   R GD GP G  G  G+KG  GE G  
Sbjct: 918  GPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQP 977

Query: 314  GPKGYKGEKG---KRGIDGVDGVKGEMGYPGLPGCKGSPG------FDGIQGPPGPKGDP 364
            GP G  G  G   +RGI G+ G +GE G PGLPG  G+PG        G +GPPGP G P
Sbjct: 978  GPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPP 1037

Query: 365  GAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGE- 423
            G+ G  GE G  G  G  G PG  G  G+ G  G+PGP G  G  G  G PGP GAPG+ 
Sbjct: 1038 GSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDA 1097

Query: 424  --RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE 481
              RG PG RGP G PG  G RG PG  GP+GD+G  G  G  G  G  G  G +G  G  
Sbjct: 1098 GQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPP 1157

Query: 482  GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKG 541
            GP G +G+ G PGP GP G PG +G  G++G            PG  G  G PG+ G+ G
Sbjct: 1158 GPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGN-----------PGPLGPIGPPGVRGSVG 1206

Query: 542  YPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGH 585
              G +G  GE                       GP GP GPPGH
Sbjct: 1207 EAGPEGPPGEP----------------------GPPGPPGPPGH 1228



 Score =  259 bits (662), Expect = 9e-69
 Identities = 157/371 (42%), Positives = 181/371 (48%), Gaps = 39/371 (10%)

Query: 247 CCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGS 306
           CC   C    G        G +G++G+PGL       G  GRPG  GP G QG +GE   
Sbjct: 92  CCPV-CSQTPGGGNTNFGRGRKGQKGEPGLVPVV--TGIRGRPGPAGPPGSQGPRGE--- 145

Query: 307 RGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD--- 363
                 RGPKG  G +G +GIDG  GV G+ G PG PG    PG DG+  P   +     
Sbjct: 146 ------RGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLD 199

Query: 364 ------------PGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD 411
                       PG+ G  G +G  G  G+ G  G +GP G+ G PG  GP G +G  G 
Sbjct: 200 EKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGP 259

Query: 412 EGNPGPDGAPGERGGPGERGPRGTPGTR---GPRGDPGEAGPQGDQGREGP---VGVPGD 465
            G PG DG PG  G PGE G  G+PG R   G  G PG  G +G +G EGP   VG PG 
Sbjct: 260 PGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGS 319

Query: 466 PGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGF 524
            GEAGP GP G  G  GP G  G RG  GP G PG  G  G  G+ GP G  G  G  GF
Sbjct: 320 KGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGF 379

Query: 525 PGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNND-----IAPRGVKGAKGYRGPEGP 579
           PG PG +G  G  G +G  G +G  GE G PG   +      I   G  GAKG  G  G 
Sbjct: 380 PGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGT 439

Query: 580 QGPPGHQGPPG 590
            GPPG  GPPG
Sbjct: 440 SGPPGSAGPPG 450



 Score =  145 bits (366), Expect = 2e-34
 Identities = 79/167 (47%), Positives = 91/167 (54%), Gaps = 12/167 (7%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            RG PG  G PG +G  G PG  G  G+AG  G PG  GP+G  G  G++G  G +G RG 
Sbjct: 1070 RGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGD 1129

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375
            KG  G++G RG  G  G  G  G PG PG  G  G  GI GP GP+G PG  G  G++G 
Sbjct: 1130 KGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGN 1189

Query: 376  PGADGEAGRPG---SSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDG 419
            PG  G  G PG   S G +G EG PGEPGPP         G PGP G
Sbjct: 1190 PGPLGPIGPPGVRGSVGEAGPEGPPGEPGPP---------GPPGPPG 1227



 Score =  133 bits (335), Expect = 8e-31
 Identities = 74/161 (45%), Positives = 88/161 (54%), Gaps = 18/161 (11%)

Query: 253  QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312
            Q A G PG  G PG  G+RG    PG +G  G PGR G  G  G QG +G+KG  G++G 
Sbjct: 1082 QGAPGTPGPVGAPGDAGQRGD---PGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGD 1138

Query: 313  RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372
            RG KG++G  G +G+            PG PG  G  G  GI GP GP+G PG  G  G+
Sbjct: 1139 RGQKGHRGFTGLQGL------------PGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGK 1186

Query: 373  KGEPGADGEAGRP---GSSGPSGDEGQPGEPGPPGEKGEAG 410
            +G PG  G  G P   GS G +G EG PGEPGPPG  G  G
Sbjct: 1187 EGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPG 1227



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 43/127 (33%), Positives = 52/127 (40%), Gaps = 30/127 (23%)

Query: 466 PGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFP 525
           PGE  P+  +        PG        G  G  G+PGL+       P   G  G PG  
Sbjct: 89  PGECCPVCSQ-------TPGGGNTNFGRGRKGQKGEPGLV-------PVVTGIRGRPGPA 134

Query: 526 GYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGH 585
           G PG++G  G  G KG PG +G                P+G+ G  G  G  G  GPPGH
Sbjct: 135 GPPGSQGPRGERGPKGRPGPRG----------------PQGIDGEPGVPGQPGAPGPPGH 178

Query: 586 QGPPGPD 592
              PGPD
Sbjct: 179 PSHPGPD 185


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score =  305 bits (781), Expect = 1e-82
 Identities = 182/428 (42%), Positives = 209/428 (48%), Gaps = 98/428 (22%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            GPPG+ G+ G +GE G PG  G KG  G+ G PG  GP+G  G  G  G+ GE G+RGP+
Sbjct: 989  GPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQ 1048

Query: 317  GYKGEKGK---------------RGIDGVDGVKGE------MGYPGLPGCKGSPGFDGIQ 355
            G+ G KG                +G+ G  G KGE      MG PG PG +G  G +G  
Sbjct: 1049 GHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGAD 1108

Query: 356  GPPGPKGDPGAFGLKGEKGEPGADGE---AGRPGSSGP------SGDEGQPGEPGPPGEK 406
            GP GP G  G  G  GEKGEPG  G     G PG  GP       G+ GQPGEPGPPG K
Sbjct: 1109 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK 1168

Query: 407  GEAGDE---GNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEA------------GPQ 451
            G  GD+   GNPGP G PG+ G PGE GPRG  G +G RG+ GE             GP 
Sbjct: 1169 GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPP 1228

Query: 452  GDQGREGPVGVPGD------------------PGEAGPIGPKGYRGDEGP---------- 483
            G  G+ GP G PG                   PG+ GP+GP G  G  GP          
Sbjct: 1229 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1288

Query: 484  -----PGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN----------GTEGFPGFPGYP 528
                 PG+ G  G PGP GPPG PGL G+ G  G  G+          G +G  G  G P
Sbjct: 1289 GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1348

Query: 529  GNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGP------QGP 582
            G +G+PG  G  G PG  G  G  G PG       P G KGAKG  GP GP      QGP
Sbjct: 1349 GPQGSPGQKGEMGIPGASGPIGPGGPPGLP----GPAGPKGAKGATGPGGPKGEKGVQGP 1404

Query: 583  PGHQGPPG 590
            PGH GPPG
Sbjct: 1405 PGHPGPPG 1412



 Score =  297 bits (760), Expect = 4e-80
 Identities = 164/341 (48%), Positives = 189/341 (55%), Gaps = 20/341 (5%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
           G PG RG  G +G RG  G  GEKGE G PG  GD+G  G +G  G  GSRGE G  GPK
Sbjct: 629 GYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPK 688

Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376
           G  G  G  G  G+ G KG++G PGLPG      + G QGP G  G PG  G  GEKG  
Sbjct: 689 GRTGPTGDPGPPGLMGEKGKLGVPGLPG------YPGRQGPKGSLGFPGFPGASGEKGAR 742

Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436
           G  G++G  G  GP+G  GQ G  G  G+ G  G  G  GP G PGERG PG +GP G P
Sbjct: 743 GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 802

Query: 437 GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPA 496
           G +GP G PG+ G  G  G+ G VG  G  G  GP G  G +G  G  G  G RG PGP 
Sbjct: 803 GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 862

Query: 497 GPPGDPGLMGERGEDG-------PAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDE 549
           GPPG+ GL G  G++G       P   G +G  G  G+PG RG P   GT G PGLKG+E
Sbjct: 863 GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLP---GTAGGPGLKGNE 919

Query: 550 GEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           G +G PG   +     G +GA G  GP GP G PG QGPPG
Sbjct: 920 GPSGPPGPAGSP----GERGAAGSGGPIGPPGRPGPQGPPG 956



 Score =  292 bits (748), Expect = 1e-78
 Identities = 166/370 (44%), Positives = 199/370 (53%), Gaps = 38/370 (10%)

Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312
           Q  RGP GL G PG  G RG+ G  G +G  GDPG  GD G  G  G+ GEKG RG+ G+
Sbjct: 433 QGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGA 492

Query: 313 RGPKGYKGEKGKRGID------------GVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP 360
           +G  G  GE G+RG D            G  G+ G  G PG+PG  G  G DG QGP G 
Sbjct: 493 QGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGS 552

Query: 361 KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA 420
            G  G  G  G++G PG  G  G  G+ GP G++G  G+PG PG  G  G  G+PG +G 
Sbjct: 553 LGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGP 612

Query: 421 PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480
           PG +G  G  GP+G  G  GPRG  G  G +G +G +G  G  G PG  G IG KG RG+
Sbjct: 613 PGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGE 672

Query: 481 EGPPGS------EGARGAPGPAGPPGDPGLMGERGEDGPAG----------NGTEGFPGF 524
            G PGS      EG +G  GP G PG PGLMGE+G+ G  G           G+ GFPGF
Sbjct: 673 VGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGF 732

Query: 525 PGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGV---KGAKGYRGPEGPQG 581
           PG  G +GA G++G  G  G +G  G  G  G       PRG     GAKG  G +GP G
Sbjct: 733 PGASGEKGARGLSGKSGPRGERGPTGPRGQRG-------PRGATGKSGAKGTSGGDGPHG 785

Query: 582 PPGHQGPPGP 591
           PPG +G PGP
Sbjct: 786 PPGERGLPGP 795



 Score =  291 bits (745), Expect = 2e-78
 Identities = 173/408 (42%), Positives = 205/408 (50%), Gaps = 72/408 (17%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGE---KGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG-- 311
            GPPGL G+ G  G  G PG PG    KG  G PG PG  G  G +G+ G+ G RGE+G  
Sbjct: 698  GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 757

Query: 312  ----SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAF 367
                 RGP+G  G+ G +G  G DG  G  G  GLPG +G  GF G +GPPGP G  G  
Sbjct: 758  GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLP 817

Query: 368  GLKGEKGEPGADGEAGRPG------------SSGPSGDEGQPGEPGPPGEKG------EA 409
            G  G++GE G  G+ G PG             +GP G+ G PG PGPPGE+G      + 
Sbjct: 818  GHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKE 877

Query: 410  GDEGNPGPDGAPGE------RGGPGER---------------------GPRGTPGTRGPR 442
            G +G+PGP GAPG+      RG PGER                     GP G+PG RG  
Sbjct: 878  GTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAA 937

Query: 443  GDPGEAGPQGDQGREGPVGVPGD---PGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPP 499
            G  G  GP G  G +GP G  G+   PGE GPIGP G  G +GP G  G  G PG AG  
Sbjct: 938  GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGED 997

Query: 500  GDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDD 558
            GD G +G+ G+ G  GN G  G PG PG  G  G PG  G  G PG +G +G  G  GD+
Sbjct: 998  GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1057

Query: 559  NND--------------IAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592
                               P G KG  G  GP GP GPPG +GP GP+
Sbjct: 1058 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPN 1105



 Score =  281 bits (719), Expect = 2e-75
 Identities = 158/346 (45%), Positives = 182/346 (52%), Gaps = 20/346 (5%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQG------MKGEKGSRGEK 310
            GPPG  G  G  G  G+ G+PGEKG  G  GR G  GPVG  G      + GE G +GE 
Sbjct: 944  GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 1003

Query: 311  GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370
            G  G KG KG KG+ G  G  G  G +G PG  G  G PG  G QG  G KGD G  G  
Sbjct: 1004 GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFN 1063

Query: 371  GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPG---ERGGP 427
            G  G  G  G  G  G  G +GD G  G PGPPG +G AG  G  GP G PG     G P
Sbjct: 1064 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPP 1123

Query: 428  GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487
            GE+G  G  G+ G +G+PG  GP+G++G +G  G PG+P   GP GPKG  GD+GP G+ 
Sbjct: 1124 GEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEP---GPPGPKGPTGDDGPKGNP 1180

Query: 488  GARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGTKGYPGLK 546
            G  G PG  GPPG+ G  G+ G  G  G +G  G PG PG  G  G PG  G +G  G  
Sbjct: 1181 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1240

Query: 547  GDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592
            G EG  G  G        +G  GA G  G  GP GP G  G PGPD
Sbjct: 1241 GSEGRQGGKG-------AKGDPGAIGAPGKTGPVGPAGPAGKPGPD 1279



 Score =  279 bits (714), Expect = 8e-75
 Identities = 164/350 (46%), Positives = 183/350 (52%), Gaps = 26/350 (7%)

Query: 257  GPPGLRGDPGFEGERGKPGL---PGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSR 313
            GPPG RG PG +G  G PG    PG  G+ G PG PG  G VG+QG  G  G  G  G +
Sbjct: 785  GPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ 844

Query: 314  GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373
            G  G  G  G+RG  G  G  GE G   LPG  G  G  G  GPPG  G  G  GL+G  
Sbjct: 845  GAAGETGPMGERGHPGPPGPPGEQG---LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFP 901

Query: 374  GEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD------EGNPGPDGAP---GER 424
            GE G  G AG PG  G  G  G PG  G PGE+G AG        G PGP G P   GE+
Sbjct: 902  GERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEK 961

Query: 425  GGPGER---GPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE 481
            G PGE+   GP G  G +GP G PG AGP G  G +G  G  GDPG+ G  G KG  G  
Sbjct: 962  GVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPP 1021

Query: 482  GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTK 540
            GPPG  G  G PG AG  G+PG  G +G  G  G+ GT GF G PG  G +G PG +G K
Sbjct: 1022 GPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEK 1081

Query: 541  GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
            G  G  G  G  G PG       PRG  G  G  GP+GP G  G+ GPPG
Sbjct: 1082 GETGDVGPMGPPGPPG-------PRGPAGPNGADGPQGPPGGVGNLGPPG 1124



 Score =  279 bits (713), Expect = 1e-74
 Identities = 161/377 (42%), Positives = 189/377 (50%), Gaps = 51/377 (13%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGE------ 309
            RG PG  G PG +G  G  G  G KG+ G PG PG  GP G +G  GE+G  G       
Sbjct: 856  RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGL 915

Query: 310  KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGL 369
            KG+ GP G  G  G  G  G  G  G +G PG PG +G PG  G +G PG KG  G  G 
Sbjct: 916  KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGR 975

Query: 370  KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGE 429
             G +G  G  G AG PG +G  GD+G+ G+PG  G KG  G+ G PGP G  G  G PG 
Sbjct: 976  DGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1035

Query: 430  RGPRGTPGTRGPRGD------------------------PGEAGPQGDQGREGPVGVPGD 465
             G  G PG RGP+G                         PG +G +G+ G  GP+G PG 
Sbjct: 1036 AGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP 1095

Query: 466  PGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGD---PGLMGE---------RGEDGP 513
            PG  GP GP G  G +GPPG  G  G PG  G PG+   PG+ GE         RGE G 
Sbjct: 1096 PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGE 1155

Query: 514  AGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573
            +G      PG PG PG +G  G +G KG PG  G  G+ G PG+      PRG  GAKG 
Sbjct: 1156 SGQ-----PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEG----GPRGQDGAKGD 1206

Query: 574  RGPEGPQGPPGHQGPPG 590
            RG +G  G PG  GP G
Sbjct: 1207 RGEDGEPGQPGSPGPTG 1223



 Score =  277 bits (709), Expect = 3e-74
 Identities = 165/378 (43%), Positives = 194/378 (51%), Gaps = 45/378 (11%)

Query: 253  QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP---VGYQGMKGEKGSRGE 309
            Q   G PG +G PG  G+ G PG PG++GE G  G+ G  GP   VG QG  GE G  GE
Sbjct: 796  QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 855

Query: 310  KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPG---FDGIQGPPGPKGDPGA 366
            +G  GP G  GE+G  G  G +G KG+ G PG PG  G  G   F G +G PG  G PG 
Sbjct: 856  RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGL 915

Query: 367  FGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGP------------PGEKGEAGDEGN 414
             G +G  G PG  G  G  G++G  G  G PG PGP            PGEKG  G  G 
Sbjct: 916  KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGR 975

Query: 415  ---------PGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVP-- 463
                     PGP G PG  G  G++G  G PG +G +G+ GE GP G  G  GPVG P  
Sbjct: 976  DGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1035

Query: 464  ----GDPGEAGPIGPKGYRGDE------GPPGSEGARGAPGPAGPPGDPGLMGERGEDGP 513
                G+PG  GP G  G +GDE      GPPG  G +G PGP+G  G+ G +G  G  GP
Sbjct: 1036 AGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP 1095

Query: 514  AGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573
               G  G  G  G  G +G PG  G  G PG KG+ GE+G PG         GVKG +G 
Sbjct: 1096 P--GPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEP----GVKGPRGE 1149

Query: 574  RGPEGPQGPPGHQGPPGP 591
            RG +G  G PG  GPPGP
Sbjct: 1150 RGEKGESGQPGEPGPPGP 1167



 Score =  277 bits (708), Expect = 4e-74
 Identities = 163/387 (42%), Positives = 190/387 (49%), Gaps = 55/387 (14%)

Query: 256 RGPPGLRGDPGFEGERGKPG-------------------------------------LPG 278
           RGPPG  G PG +G  G PG                                     L G
Sbjct: 342 RGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRG 401

Query: 279 EKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMG 338
             G  G  GRPG LG  G  G+KGE G  G +G RGP+G  G  GK G  G  G  G  G
Sbjct: 402 PPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARG 461

Query: 339 YPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGE---------AGRPGSSG 389
            PG PG KG  GFDG+ G PG KG  G  G +G  G PG DGE          G PG SG
Sbjct: 462 MPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESG 521

Query: 390 PSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAG 449
           P G  G  G PG PG  G  G +G  GP G+ G +G PG  G +GTPGT+G  G  G  G
Sbjct: 522 PRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIG 581

Query: 450 PQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERG 509
           P G++G +G  G+PG PG     GP G+ G EGPPG++G +G  GP GP G PG  G +G
Sbjct: 582 PHGEKGPQGKPGLPGMPGSD---GPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKG 638

Query: 510 EDGPAG----NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPG--DDNNDIA 563
            DG  G     G +G  GFPG+ G+ G  G  G  G PG +G++G  G  G      D  
Sbjct: 639 VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG 698

Query: 564 PRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           P G+ G KG  G  G  G PG QGP G
Sbjct: 699 PPGLMGEKGKLGVPGLPGYPGRQGPKG 725



 Score =  272 bits (696), Expect = 1e-72
 Identities = 157/358 (43%), Positives = 186/358 (51%), Gaps = 25/358 (6%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            RG  G RG  G  G +G  G  G  G  G+ G PG  GP G+ G KG  G  G+ G  G 
Sbjct: 760  RGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGH 819

Query: 316  KGYKGE---KGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372
             G +GE   +GK G  G  GV G  G  G  G  G  G  G  GPPG +G PG  G +G 
Sbjct: 820  PGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 879

Query: 373  KGEPGADGEAGRPGSSGP---SGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGG--- 426
            KG+PG  G  G+ G +G     G+ G PG  G PG KG  G  G PGP G+PGERG    
Sbjct: 880  KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 939

Query: 427  ------PGERGPRGTPGTRGPRGDPGEAGPQGDQGR---EGPVGVPGDPGEAGPIGPKGY 477
                  PG  GP+G PG  G +G PGE GP G  GR   +GPVG+PG  G  G  G  G 
Sbjct: 940  GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGD 999

Query: 478  RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGIN 537
            +G+ G PG +G +G  G  GPPG PG +G  G+ G A  G +G PG  G  G+ GA G  
Sbjct: 1000 KGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAA--GADGEPGARGPQGHFGAKGDE 1057

Query: 538  GTKGYPGLKGDEGEAGDPG-----DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
            GT+G+ G  G  G  G PG      +  D+ P G  G  G RGP GP G  G QGPPG
Sbjct: 1058 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG 1115



 Score =  264 bits (674), Expect = 4e-70
 Identities = 166/390 (42%), Positives = 188/390 (48%), Gaps = 58/390 (14%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK------ 310
           GPPG  G  G  G    PG+ G  G  GDPG  G  G  G  G  G  G  G        
Sbjct: 313 GPPGPEGPAGLIGP---PGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFR 369

Query: 311 -----GSRGPKGYKGE--------------KGKRGIDGVDGVKGEMGYPGLPGCKGSPGF 351
                G +GP     E              +G  G  G  G  G +G PG PG KG  G 
Sbjct: 370 FGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGD 429

Query: 352 DGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD 411
            G QGP GP+G  G  G  G +G  GADG  G PG  G  GD G  G PG PGEKG  GD
Sbjct: 430 LGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGD 489

Query: 412 ---EGNPGPDGAPGERGGPGERGPRGTPGTRGPR------GDPGEAGPQGDQGREGPVGV 462
              +G PGP G  GERG  GE GPRG PG  GPR      G PG  GP G +G +GP G 
Sbjct: 490 TGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGP 549

Query: 463 PGD---PGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GT 518
            G     GE GP G +G  G +G PG +GA G  G  GP G PGL G  G DGP G+ G 
Sbjct: 550 KGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGK 609

Query: 519 EGFPGFP------------GYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNN-----D 561
           EG PG              GYPG RG  G++G +G  G KG++GE G PG   +     D
Sbjct: 610 EGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGD 669

Query: 562 IAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
               GV G++G  GPEGP+G  G  G PGP
Sbjct: 670 RGEVGVPGSRGEDGPEGPKGRTGPTGDPGP 699



 Score =  243 bits (621), Expect = 5e-64
 Identities = 130/276 (47%), Positives = 155/276 (56%), Gaps = 9/276 (3%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            +GP G RG+ G  G+ G+PG PG KG  GD G  G+ GPVG+ G  G  G  G +G  G 
Sbjct: 1144 KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGA 1203

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKG---SPGFDGIQGPPGPKGDPGAFGLKGE 372
            KG +GE G+ G  G  G  GE G PG  G +G   SPG +G QG  G KGDPGA G  G+
Sbjct: 1204 KGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGK 1263

Query: 373  KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGP 432
             G  G  G AG+PG  G  G  G  G+ G PG  G+AG  G  GP G PG RG  G +G 
Sbjct: 1264 TGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1323

Query: 433  RGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGD------PGEAGPIGPKGYRGDEGPPGS 486
            +G PG  G  G PGE G +GD+G  GP G PG       PG +GPIGP G  G  GP G 
Sbjct: 1324 KGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGP 1383

Query: 487  EGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFP 522
            +GA+GA GP GP G+ G+ G  G  GP G   +  P
Sbjct: 1384 KGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1419



 Score =  201 bits (510), Expect = 4e-51
 Identities = 136/370 (36%), Positives = 164/370 (44%), Gaps = 108/370 (29%)

Query: 309 EKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK------- 361
           E+ + GP+G KGEKG+  +            PG+           ++GPPGP+       
Sbjct: 286 EEAAHGPRGLKGEKGEPAVLE----------PGML----------VEGPPGPEGPAGLIG 325

Query: 362 -----------GDPGAFGLKGEKGEPGADGEAGRPGSS---------------------- 388
                      GDPG  G  G  G PG+DG  G PG+S                      
Sbjct: 326 PPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQE 385

Query: 389 ------------------GPSGDEGQP---GEPGPPGEKGEAGDEGNPGPDGAPGERGGP 427
                             GP G  G+P   G+PG PG KGE+GD G  GP G  G  G P
Sbjct: 386 AQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPP 445

Query: 428 GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGE---------AGPIGPKGYR 478
           G+ G RG  G  G RG PG+ G +GD+G +G  G+PG+ G           GP G  G R
Sbjct: 446 GKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGER 505

Query: 479 GDEGP------PGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-------NGTEGFPGFP 525
           GD+G       PG  G RG  GP GPPG PG  G RG DGP G        G  G PG  
Sbjct: 506 GDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQ 565

Query: 526 GYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAP-----RGVKGAKGYRGPEGPQ 580
           G PG +G PG  G  G  G KG +G+ G PG   +D  P      G  G KG +GP GPQ
Sbjct: 566 GTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQ 625

Query: 581 GPPGHQGPPG 590
           GP G+ GP G
Sbjct: 626 GPLGYPGPRG 635



 Score =  199 bits (505), Expect = 1e-50
 Identities = 119/281 (42%), Positives = 140/281 (49%), Gaps = 20/281 (7%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGD---PGRPGDLGPVGYQGMKGEKGSRGEKGSR 313
            GP G  GDPG  GE G  G  G KG+ G+   PG+PG  GP G  G  G  G RG  GS 
Sbjct: 1181 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1240

Query: 314  GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373
            G +G +G KG +G  G  G  G+ G  G  G  G PG DG++G PG  G  G  G  G+ 
Sbjct: 1241 GSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQA 1300

Query: 374  GEPGADGEAGRPGSSGPSGDEGQPGEP------GPPGEKGEAGDEGNPGPDGAPGERGGP 427
            G PG  G  G PG  G +G +G+ G P      GPPGE+GE GD G PGP G+PG++G  
Sbjct: 1301 GPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEM 1360

Query: 428  GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487
            G  G  G  G  GP G PG AGP+G +G  GP          GP G KG +G  G PG  
Sbjct: 1361 GIPGASGPIGPGGPPGLPGPAGPKGAKGATGP---------GGPKGEKGVQGPPGHPGPP 1411

Query: 488  GARGAPGPAGPPGDP--GLMGERGEDGPAGNGTEGFPGFPG 526
            G    P P   P      + G R         T G PG PG
Sbjct: 1412 GEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1452



 Score =  186 bits (472), Expect = 1e-46
 Identities = 114/269 (42%), Positives = 132/269 (49%), Gaps = 27/269 (10%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS--- 312
            RG  G +GD G +GE G+PG PG  GE G PG  G  GP G  G +G +G +G KG    
Sbjct: 1198 RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGA 1257

Query: 313  ------RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366
                   GP G  G  GK G DG+ G+ G +G  G PG  G  G     GP GP G PG 
Sbjct: 1258 IGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAG---PPGPVGPPGLPGL 1314

Query: 367  ---FGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGE 423
                G KGEKG PG  G  G PG  G  GD G PG  G PG+KGE G  G  GP G  G 
Sbjct: 1315 RGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP 1374

Query: 424  RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGP-----KGYR 478
             G PG  GP+G  G  GP       GP+G++G +GP G PG PGE     P     K  R
Sbjct: 1375 PGLPGPAGPKGAKGATGP------GGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRR 1428

Query: 479  GDEGPPGSEGARGAPGPAGPPGDPGLMGE 507
              +G    +     P   G PG PG + E
Sbjct: 1429 SVDGSRLMQEDEAIP-TGGAPGSPGGLEE 1456



 Score =  182 bits (461), Expect = 2e-45
 Identities = 115/280 (41%), Positives = 131/280 (46%), Gaps = 69/280 (24%)

Query: 357 PPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPG 416
           PP  +   G  GLKGEKGEP        PG       EG PG  GP G  G  G +GNPG
Sbjct: 283 PPLEEAAHGPRGLKGEKGEPAVL----EPGMLV----EGPPGPEGPAGLIGPPGIQGNPG 334

Query: 417 PDGAPGERGGPGERGPRGTPGTRGPRGDP------------------------------- 445
           P G PGERG PG  G  G+ G  GP G                                 
Sbjct: 335 PVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQ 394

Query: 446 ------GEAGPQGDQGREGPVGVPGDP------GEAGPIGPKGYRGDEGPPGSEGAR--- 490
                 G  GP G  GR GP+G PG P      G+ GP GP+G +G  GPPG  G R   
Sbjct: 395 ARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRA 454

Query: 491 GAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEG 550
           GA G  G PGDPG+ G+R           GF G PG PG +G  G  G +G PG  G++G
Sbjct: 455 GADGARGMPGDPGVKGDR-----------GFDGLPGLPGEKGHRGDTGAQGLPGPPGEDG 503

Query: 551 EAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           E GD G    +I PRG+ G  G RG  GP+GPPG  GPPG
Sbjct: 504 ERGDDG----EIGPRGLPGESGPRGLLGPKGPPGIPGPPG 539



 Score = 31.2 bits (69), Expect = 5.2
 Identities = 13/25 (52%), Positives = 16/25 (64%)

Query: 255  ARGPPGLRGDPGFEGERGKPGLPGE 279
            A GP G +G+ G +G  G PG PGE
Sbjct: 1389 ATGPGGPKGEKGVQGPPGHPGPPGE 1413


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score =  305 bits (781), Expect = 1e-82
 Identities = 182/428 (42%), Positives = 209/428 (48%), Gaps = 98/428 (22%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            GPPG+ G+ G +GE G PG  G KG  G+ G PG  GP+G  G  G  G+ GE G+RGP+
Sbjct: 968  GPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQ 1027

Query: 317  GYKGEKGK---------------RGIDGVDGVKGE------MGYPGLPGCKGSPGFDGIQ 355
            G+ G KG                +G+ G  G KGE      MG PG PG +G  G +G  
Sbjct: 1028 GHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGAD 1087

Query: 356  GPPGPKGDPGAFGLKGEKGEPGADGE---AGRPGSSGP------SGDEGQPGEPGPPGEK 406
            GP GP G  G  G  GEKGEPG  G     G PG  GP       G+ GQPGEPGPPG K
Sbjct: 1088 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK 1147

Query: 407  GEAGDE---GNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEA------------GPQ 451
            G  GD+   GNPGP G PG+ G PGE GPRG  G +G RG+ GE             GP 
Sbjct: 1148 GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPP 1207

Query: 452  GDQGREGPVGVPGD------------------PGEAGPIGPKGYRGDEGP---------- 483
            G  G+ GP G PG                   PG+ GP+GP G  G  GP          
Sbjct: 1208 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1267

Query: 484  -----PGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN----------GTEGFPGFPGYP 528
                 PG+ G  G PGP GPPG PGL G+ G  G  G+          G +G  G  G P
Sbjct: 1268 GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1327

Query: 529  GNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGP------QGP 582
            G +G+PG  G  G PG  G  G  G PG       P G KGAKG  GP GP      QGP
Sbjct: 1328 GPQGSPGQKGEMGIPGASGPIGPGGPPGLP----GPAGPKGAKGATGPGGPKGEKGVQGP 1383

Query: 583  PGHQGPPG 590
            PGH GPPG
Sbjct: 1384 PGHPGPPG 1391



 Score =  297 bits (760), Expect = 4e-80
 Identities = 164/341 (48%), Positives = 189/341 (55%), Gaps = 20/341 (5%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
           G PG RG  G +G RG  G  GEKGE G PG  GD+G  G +G  G  GSRGE G  GPK
Sbjct: 608 GYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPK 667

Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376
           G  G  G  G  G+ G KG++G PGLPG      + G QGP G  G PG  G  GEKG  
Sbjct: 668 GRTGPTGDPGPPGLMGEKGKLGVPGLPG------YPGRQGPKGSLGFPGFPGASGEKGAR 721

Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436
           G  G++G  G  GP+G  GQ G  G  G+ G  G  G  GP G PGERG PG +GP G P
Sbjct: 722 GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 781

Query: 437 GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPA 496
           G +GP G PG+ G  G  G+ G VG  G  G  GP G  G +G  G  G  G RG PGP 
Sbjct: 782 GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 841

Query: 497 GPPGDPGLMGERGEDG-------PAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDE 549
           GPPG+ GL G  G++G       P   G +G  G  G+PG RG P   GT G PGLKG+E
Sbjct: 842 GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLP---GTAGGPGLKGNE 898

Query: 550 GEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           G +G PG   +     G +GA G  GP GP G PG QGPPG
Sbjct: 899 GPSGPPGPAGSP----GERGAAGSGGPIGPPGRPGPQGPPG 935



 Score =  292 bits (748), Expect = 1e-78
 Identities = 166/370 (44%), Positives = 199/370 (53%), Gaps = 38/370 (10%)

Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312
           Q  RGP GL G PG  G RG+ G  G +G  GDPG  GD G  G  G+ GEKG RG+ G+
Sbjct: 412 QGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGA 471

Query: 313 RGPKGYKGEKGKRGID------------GVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP 360
           +G  G  GE G+RG D            G  G+ G  G PG+PG  G  G DG QGP G 
Sbjct: 472 QGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGS 531

Query: 361 KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA 420
            G  G  G  G++G PG  G  G  G+ GP G++G  G+PG PG  G  G  G+PG +G 
Sbjct: 532 LGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGP 591

Query: 421 PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480
           PG +G  G  GP+G  G  GPRG  G  G +G +G +G  G  G PG  G IG KG RG+
Sbjct: 592 PGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGE 651

Query: 481 EGPPGS------EGARGAPGPAGPPGDPGLMGERGEDGPAG----------NGTEGFPGF 524
            G PGS      EG +G  GP G PG PGLMGE+G+ G  G           G+ GFPGF
Sbjct: 652 VGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGF 711

Query: 525 PGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGV---KGAKGYRGPEGPQG 581
           PG  G +GA G++G  G  G +G  G  G  G       PRG     GAKG  G +GP G
Sbjct: 712 PGASGEKGARGLSGKSGPRGERGPTGPRGQRG-------PRGATGKSGAKGTSGGDGPHG 764

Query: 582 PPGHQGPPGP 591
           PPG +G PGP
Sbjct: 765 PPGERGLPGP 774



 Score =  291 bits (745), Expect = 2e-78
 Identities = 173/408 (42%), Positives = 205/408 (50%), Gaps = 72/408 (17%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGE---KGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG-- 311
            GPPGL G+ G  G  G PG PG    KG  G PG PG  G  G +G+ G+ G RGE+G  
Sbjct: 677  GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 736

Query: 312  ----SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAF 367
                 RGP+G  G+ G +G  G DG  G  G  GLPG +G  GF G +GPPGP G  G  
Sbjct: 737  GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLP 796

Query: 368  GLKGEKGEPGADGEAGRPG------------SSGPSGDEGQPGEPGPPGEKG------EA 409
            G  G++GE G  G+ G PG             +GP G+ G PG PGPPGE+G      + 
Sbjct: 797  GHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKE 856

Query: 410  GDEGNPGPDGAPGE------RGGPGER---------------------GPRGTPGTRGPR 442
            G +G+PGP GAPG+      RG PGER                     GP G+PG RG  
Sbjct: 857  GTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAA 916

Query: 443  GDPGEAGPQGDQGREGPVGVPGD---PGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPP 499
            G  G  GP G  G +GP G  G+   PGE GPIGP G  G +GP G  G  G PG AG  
Sbjct: 917  GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGED 976

Query: 500  GDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDD 558
            GD G +G+ G+ G  GN G  G PG PG  G  G PG  G  G PG +G +G  G  GD+
Sbjct: 977  GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1036

Query: 559  NND--------------IAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592
                               P G KG  G  GP GP GPPG +GP GP+
Sbjct: 1037 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPN 1084



 Score =  281 bits (719), Expect = 2e-75
 Identities = 158/346 (45%), Positives = 182/346 (52%), Gaps = 20/346 (5%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQG------MKGEKGSRGEK 310
            GPPG  G  G  G  G+ G+PGEKG  G  GR G  GPVG  G      + GE G +GE 
Sbjct: 923  GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 982

Query: 311  GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370
            G  G KG KG KG+ G  G  G  G +G PG  G  G PG  G QG  G KGD G  G  
Sbjct: 983  GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFN 1042

Query: 371  GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPG---ERGGP 427
            G  G  G  G  G  G  G +GD G  G PGPPG +G AG  G  GP G PG     G P
Sbjct: 1043 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPP 1102

Query: 428  GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487
            GE+G  G  G+ G +G+PG  GP+G++G +G  G PG+P   GP GPKG  GD+GP G+ 
Sbjct: 1103 GEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEP---GPPGPKGPTGDDGPKGNP 1159

Query: 488  GARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGTKGYPGLK 546
            G  G PG  GPPG+ G  G+ G  G  G +G  G PG PG  G  G PG  G +G  G  
Sbjct: 1160 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1219

Query: 547  GDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592
            G EG  G  G        +G  GA G  G  GP GP G  G PGPD
Sbjct: 1220 GSEGRQGGKG-------AKGDPGAIGAPGKTGPVGPAGPAGKPGPD 1258



 Score =  279 bits (714), Expect = 8e-75
 Identities = 164/350 (46%), Positives = 183/350 (52%), Gaps = 26/350 (7%)

Query: 257  GPPGLRGDPGFEGERGKPGL---PGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSR 313
            GPPG RG PG +G  G PG    PG  G+ G PG PG  G VG+QG  G  G  G  G +
Sbjct: 764  GPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ 823

Query: 314  GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373
            G  G  G  G+RG  G  G  GE G   LPG  G  G  G  GPPG  G  G  GL+G  
Sbjct: 824  GAAGETGPMGERGHPGPPGPPGEQG---LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFP 880

Query: 374  GEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD------EGNPGPDGAP---GER 424
            GE G  G AG PG  G  G  G PG  G PGE+G AG        G PGP G P   GE+
Sbjct: 881  GERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEK 940

Query: 425  GGPGER---GPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE 481
            G PGE+   GP G  G +GP G PG AGP G  G +G  G  GDPG+ G  G KG  G  
Sbjct: 941  GVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPP 1000

Query: 482  GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTK 540
            GPPG  G  G PG AG  G+PG  G +G  G  G+ GT GF G PG  G +G PG +G K
Sbjct: 1001 GPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEK 1060

Query: 541  GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
            G  G  G  G  G PG       PRG  G  G  GP+GP G  G+ GPPG
Sbjct: 1061 GETGDVGPMGPPGPPG-------PRGPAGPNGADGPQGPPGGVGNLGPPG 1103



 Score =  279 bits (713), Expect = 1e-74
 Identities = 161/377 (42%), Positives = 189/377 (50%), Gaps = 51/377 (13%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGE------ 309
            RG PG  G PG +G  G  G  G KG+ G PG PG  GP G +G  GE+G  G       
Sbjct: 835  RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGL 894

Query: 310  KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGL 369
            KG+ GP G  G  G  G  G  G  G +G PG PG +G PG  G +G PG KG  G  G 
Sbjct: 895  KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGR 954

Query: 370  KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGE 429
             G +G  G  G AG PG +G  GD+G+ G+PG  G KG  G+ G PGP G  G  G PG 
Sbjct: 955  DGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1014

Query: 430  RGPRGTPGTRGPRGD------------------------PGEAGPQGDQGREGPVGVPGD 465
             G  G PG RGP+G                         PG +G +G+ G  GP+G PG 
Sbjct: 1015 AGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP 1074

Query: 466  PGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGD---PGLMGE---------RGEDGP 513
            PG  GP GP G  G +GPPG  G  G PG  G PG+   PG+ GE         RGE G 
Sbjct: 1075 PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGE 1134

Query: 514  AGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573
            +G      PG PG PG +G  G +G KG PG  G  G+ G PG+      PRG  GAKG 
Sbjct: 1135 SGQ-----PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEG----GPRGQDGAKGD 1185

Query: 574  RGPEGPQGPPGHQGPPG 590
            RG +G  G PG  GP G
Sbjct: 1186 RGEDGEPGQPGSPGPTG 1202



 Score =  277 bits (709), Expect = 3e-74
 Identities = 165/378 (43%), Positives = 194/378 (51%), Gaps = 45/378 (11%)

Query: 253  QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP---VGYQGMKGEKGSRGE 309
            Q   G PG +G PG  G+ G PG PG++GE G  G+ G  GP   VG QG  GE G  GE
Sbjct: 775  QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 834

Query: 310  KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPG---FDGIQGPPGPKGDPGA 366
            +G  GP G  GE+G  G  G +G KG+ G PG PG  G  G   F G +G PG  G PG 
Sbjct: 835  RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGL 894

Query: 367  FGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGP------------PGEKGEAGDEGN 414
             G +G  G PG  G  G  G++G  G  G PG PGP            PGEKG  G  G 
Sbjct: 895  KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGR 954

Query: 415  ---------PGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVP-- 463
                     PGP G PG  G  G++G  G PG +G +G+ GE GP G  G  GPVG P  
Sbjct: 955  DGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1014

Query: 464  ----GDPGEAGPIGPKGYRGDE------GPPGSEGARGAPGPAGPPGDPGLMGERGEDGP 513
                G+PG  GP G  G +GDE      GPPG  G +G PGP+G  G+ G +G  G  GP
Sbjct: 1015 AGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP 1074

Query: 514  AGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573
               G  G  G  G  G +G PG  G  G PG KG+ GE+G PG         GVKG +G 
Sbjct: 1075 P--GPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEP----GVKGPRGE 1128

Query: 574  RGPEGPQGPPGHQGPPGP 591
            RG +G  G PG  GPPGP
Sbjct: 1129 RGEKGESGQPGEPGPPGP 1146



 Score =  277 bits (708), Expect = 4e-74
 Identities = 163/387 (42%), Positives = 190/387 (49%), Gaps = 55/387 (14%)

Query: 256 RGPPGLRGDPGFEGERGKPG-------------------------------------LPG 278
           RGPPG  G PG +G  G PG                                     L G
Sbjct: 321 RGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRG 380

Query: 279 EKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMG 338
             G  G  GRPG LG  G  G+KGE G  G +G RGP+G  G  GK G  G  G  G  G
Sbjct: 381 PPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARG 440

Query: 339 YPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGE---------AGRPGSSG 389
            PG PG KG  GFDG+ G PG KG  G  G +G  G PG DGE          G PG SG
Sbjct: 441 MPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESG 500

Query: 390 PSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAG 449
           P G  G  G PG PG  G  G +G  GP G+ G +G PG  G +GTPGT+G  G  G  G
Sbjct: 501 PRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIG 560

Query: 450 PQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERG 509
           P G++G +G  G+PG PG     GP G+ G EGPPG++G +G  GP GP G PG  G +G
Sbjct: 561 PHGEKGPQGKPGLPGMPGSD---GPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKG 617

Query: 510 EDGPAG----NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPG--DDNNDIA 563
            DG  G     G +G  GFPG+ G+ G  G  G  G PG +G++G  G  G      D  
Sbjct: 618 VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG 677

Query: 564 PRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           P G+ G KG  G  G  G PG QGP G
Sbjct: 678 PPGLMGEKGKLGVPGLPGYPGRQGPKG 704



 Score =  272 bits (696), Expect = 1e-72
 Identities = 157/358 (43%), Positives = 186/358 (51%), Gaps = 25/358 (6%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            RG  G RG  G  G +G  G  G  G  G+ G PG  GP G+ G KG  G  G+ G  G 
Sbjct: 739  RGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGH 798

Query: 316  KGYKGE---KGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372
             G +GE   +GK G  G  GV G  G  G  G  G  G  G  GPPG +G PG  G +G 
Sbjct: 799  PGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 858

Query: 373  KGEPGADGEAGRPGSSGP---SGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGG--- 426
            KG+PG  G  G+ G +G     G+ G PG  G PG KG  G  G PGP G+PGERG    
Sbjct: 859  KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 918

Query: 427  ------PGERGPRGTPGTRGPRGDPGEAGPQGDQGR---EGPVGVPGDPGEAGPIGPKGY 477
                  PG  GP+G PG  G +G PGE GP G  GR   +GPVG+PG  G  G  G  G 
Sbjct: 919  GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGD 978

Query: 478  RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGIN 537
            +G+ G PG +G +G  G  GPPG PG +G  G+ G A  G +G PG  G  G+ GA G  
Sbjct: 979  KGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAA--GADGEPGARGPQGHFGAKGDE 1036

Query: 538  GTKGYPGLKGDEGEAGDPG-----DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
            GT+G+ G  G  G  G PG      +  D+ P G  G  G RGP GP G  G QGPPG
Sbjct: 1037 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG 1094



 Score =  268 bits (684), Expect = 3e-71
 Identities = 171/415 (41%), Positives = 200/415 (48%), Gaps = 74/415 (17%)

Query: 251 ECQPARGPPGLRGD----------------PGFEGERGKPGLPGEKGEAGDPGRPGDLGP 294
           + Q A GP GL+G+                PG EG  G  G PG +G  G  G PG+ GP
Sbjct: 264 QSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGP 323

Query: 295 VGYQGMKGEKGSRGEKGS--------------RGPKGYKGE--------------KGKRG 326
            G  G+ G  G+ G  G+              +GP     E              +G  G
Sbjct: 324 PGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPG 383

Query: 327 IDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPG 386
             G  G  G +G PG PG KG  G  G QGP GP+G  G  G  G +G  GADG  G PG
Sbjct: 384 PMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPG 443

Query: 387 SSGPSGDEGQPGEPGPPGEKGEAGD---EGNPGPDGAPGERGGPGERGPRGTPGTRGPR- 442
             G  GD G  G PG PGEKG  GD   +G PGP G  GERG  GE GPRG PG  GPR 
Sbjct: 444 DPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRG 503

Query: 443 -----GDPGEAGPQGDQGREGPVGVPGD---PGEAGPIGPKGYRGDEGPPGSEGARGAPG 494
                G PG  GP G +G +GP G  G     GE GP G +G  G +G PG +GA G  G
Sbjct: 504 LLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHG 563

Query: 495 PAGPPGDPGLMGERGEDGPAGN-GTEGFPGFP------------GYPGNRGAPGINGTKG 541
             GP G PGL G  G DGP G+ G EG PG              GYPG RG  G++G +G
Sbjct: 564 EKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRG 623

Query: 542 YPGLKGDEGEAGDPGDDNN-----DIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
             G KG++GE G PG   +     D    GV G++G  GPEGP+G  G  G PGP
Sbjct: 624 LKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP 678



 Score =  243 bits (621), Expect = 5e-64
 Identities = 130/276 (47%), Positives = 155/276 (56%), Gaps = 9/276 (3%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            +GP G RG+ G  G+ G+PG PG KG  GD G  G+ GPVG+ G  G  G  G +G  G 
Sbjct: 1123 KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGA 1182

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKG---SPGFDGIQGPPGPKGDPGAFGLKGE 372
            KG +GE G+ G  G  G  GE G PG  G +G   SPG +G QG  G KGDPGA G  G+
Sbjct: 1183 KGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGK 1242

Query: 373  KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGP 432
             G  G  G AG+PG  G  G  G  G+ G PG  G+AG  G  GP G PG RG  G +G 
Sbjct: 1243 TGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1302

Query: 433  RGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGD------PGEAGPIGPKGYRGDEGPPGS 486
            +G PG  G  G PGE G +GD+G  GP G PG       PG +GPIGP G  G  GP G 
Sbjct: 1303 KGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGP 1362

Query: 487  EGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFP 522
            +GA+GA GP GP G+ G+ G  G  GP G   +  P
Sbjct: 1363 KGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1398



 Score =  199 bits (507), Expect = 9e-51
 Identities = 137/370 (37%), Positives = 165/370 (44%), Gaps = 93/370 (25%)

Query: 309 EKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK------- 361
           ++ SR  +    E   +   G  G+KGE G P +      PG   ++GPPGP+       
Sbjct: 250 QQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVL----EPGML-VEGPPGPEGPAGLIG 304

Query: 362 -----------GDPGAFGLKGEKGEPGADGEAGRPGSS---------------------- 388
                      GDPG  G  G  G PG+DG  G PG+S                      
Sbjct: 305 PPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQE 364

Query: 389 ------------------GPSGDEGQP---GEPGPPGEKGEAGDEGNPGPDGAPGERGGP 427
                             GP G  G+P   G+PG PG KGE+GD G  GP G  G  G P
Sbjct: 365 AQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPP 424

Query: 428 GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGE---------AGPIGPKGYR 478
           G+ G RG  G  G RG PG+ G +GD+G +G  G+PG+ G           GP G  G R
Sbjct: 425 GKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGER 484

Query: 479 GDEGP------PGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-------NGTEGFPGFP 525
           GD+G       PG  G RG  GP GPPG PG  G RG DGP G        G  G PG  
Sbjct: 485 GDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQ 544

Query: 526 GYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAP-----RGVKGAKGYRGPEGPQ 580
           G PG +G PG  G  G  G KG +G+ G PG   +D  P      G  G KG +GP GPQ
Sbjct: 545 GTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQ 604

Query: 581 GPPGHQGPPG 590
           GP G+ GP G
Sbjct: 605 GPLGYPGPRG 614



 Score =  199 bits (505), Expect = 1e-50
 Identities = 119/281 (42%), Positives = 140/281 (49%), Gaps = 20/281 (7%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGD---PGRPGDLGPVGYQGMKGEKGSRGEKGSR 313
            GP G  GDPG  GE G  G  G KG+ G+   PG+PG  GP G  G  G  G RG  GS 
Sbjct: 1160 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1219

Query: 314  GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373
            G +G +G KG +G  G  G  G+ G  G  G  G PG DG++G PG  G  G  G  G+ 
Sbjct: 1220 GSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQA 1279

Query: 374  GEPGADGEAGRPGSSGPSGDEGQPGEP------GPPGEKGEAGDEGNPGPDGAPGERGGP 427
            G PG  G  G PG  G +G +G+ G P      GPPGE+GE GD G PGP G+PG++G  
Sbjct: 1280 GPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEM 1339

Query: 428  GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487
            G  G  G  G  GP G PG AGP+G +G  GP          GP G KG +G  G PG  
Sbjct: 1340 GIPGASGPIGPGGPPGLPGPAGPKGAKGATGP---------GGPKGEKGVQGPPGHPGPP 1390

Query: 488  GARGAPGPAGPPGDP--GLMGERGEDGPAGNGTEGFPGFPG 526
            G    P P   P      + G R         T G PG PG
Sbjct: 1391 GEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1431



 Score =  186 bits (472), Expect = 1e-46
 Identities = 114/269 (42%), Positives = 132/269 (49%), Gaps = 27/269 (10%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS--- 312
            RG  G +GD G +GE G+PG PG  GE G PG  G  GP G  G +G +G +G KG    
Sbjct: 1177 RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGA 1236

Query: 313  ------RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366
                   GP G  G  GK G DG+ G+ G +G  G PG  G  G     GP GP G PG 
Sbjct: 1237 IGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAG---PPGPVGPPGLPGL 1293

Query: 367  ---FGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGE 423
                G KGEKG PG  G  G PG  G  GD G PG  G PG+KGE G  G  GP G  G 
Sbjct: 1294 RGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP 1353

Query: 424  RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGP-----KGYR 478
             G PG  GP+G  G  GP       GP+G++G +GP G PG PGE     P     K  R
Sbjct: 1354 PGLPGPAGPKGAKGATGP------GGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRR 1407

Query: 479  GDEGPPGSEGARGAPGPAGPPGDPGLMGE 507
              +G    +     P   G PG PG + E
Sbjct: 1408 SVDGSRLMQEDEAIP-TGGAPGSPGGLEE 1435



 Score = 31.2 bits (69), Expect = 5.2
 Identities = 13/25 (52%), Positives = 16/25 (64%)

Query: 255  ARGPPGLRGDPGFEGERGKPGLPGE 279
            A GP G +G+ G +G  G PG PGE
Sbjct: 1368 ATGPGGPKGEKGVQGPPGHPGPPGE 1392


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score =  305 bits (781), Expect = 1e-82
 Identities = 182/428 (42%), Positives = 209/428 (48%), Gaps = 98/428 (22%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            GPPG+ G+ G +GE G PG  G KG  G+ G PG  GP+G  G  G  G+ GE G+RGP+
Sbjct: 1075 GPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQ 1134

Query: 317  GYKGEKGK---------------RGIDGVDGVKGE------MGYPGLPGCKGSPGFDGIQ 355
            G+ G KG                +G+ G  G KGE      MG PG PG +G  G +G  
Sbjct: 1135 GHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGAD 1194

Query: 356  GPPGPKGDPGAFGLKGEKGEPGADGE---AGRPGSSGP------SGDEGQPGEPGPPGEK 406
            GP GP G  G  G  GEKGEPG  G     G PG  GP       G+ GQPGEPGPPG K
Sbjct: 1195 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK 1254

Query: 407  GEAGDE---GNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEA------------GPQ 451
            G  GD+   GNPGP G PG+ G PGE GPRG  G +G RG+ GE             GP 
Sbjct: 1255 GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPP 1314

Query: 452  GDQGREGPVGVPGD------------------PGEAGPIGPKGYRGDEGP---------- 483
            G  G+ GP G PG                   PG+ GP+GP G  G  GP          
Sbjct: 1315 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1374

Query: 484  -----PGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN----------GTEGFPGFPGYP 528
                 PG+ G  G PGP GPPG PGL G+ G  G  G+          G +G  G  G P
Sbjct: 1375 GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1434

Query: 529  GNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGP------QGP 582
            G +G+PG  G  G PG  G  G  G PG       P G KGAKG  GP GP      QGP
Sbjct: 1435 GPQGSPGQKGEMGIPGASGPIGPGGPPGLP----GPAGPKGAKGATGPGGPKGEKGVQGP 1490

Query: 583  PGHQGPPG 590
            PGH GPPG
Sbjct: 1491 PGHPGPPG 1498



 Score =  297 bits (760), Expect = 4e-80
 Identities = 164/341 (48%), Positives = 189/341 (55%), Gaps = 20/341 (5%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            G PG RG  G +G RG  G  GEKGE G PG  GD+G  G +G  G  GSRGE G  GPK
Sbjct: 715  GYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPK 774

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376
            G  G  G  G  G+ G KG++G PGLPG      + G QGP G  G PG  G  GEKG  
Sbjct: 775  GRTGPTGDPGPPGLMGEKGKLGVPGLPG------YPGRQGPKGSLGFPGFPGASGEKGAR 828

Query: 377  GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436
            G  G++G  G  GP+G  GQ G  G  G+ G  G  G  GP G PGERG PG +GP G P
Sbjct: 829  GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 888

Query: 437  GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPA 496
            G +GP G PG+ G  G  G+ G VG  G  G  GP G  G +G  G  G  G RG PGP 
Sbjct: 889  GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 948

Query: 497  GPPGDPGLMGERGEDG-------PAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDE 549
            GPPG+ GL G  G++G       P   G +G  G  G+PG RG P   GT G PGLKG+E
Sbjct: 949  GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLP---GTAGGPGLKGNE 1005

Query: 550  GEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
            G +G PG   +     G +GA G  GP GP G PG QGPPG
Sbjct: 1006 GPSGPPGPAGSP----GERGAAGSGGPIGPPGRPGPQGPPG 1042



 Score =  292 bits (748), Expect = 1e-78
 Identities = 166/370 (44%), Positives = 199/370 (53%), Gaps = 38/370 (10%)

Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312
           Q  RGP GL G PG  G RG+ G  G +G  GDPG  GD G  G  G+ GEKG RG+ G+
Sbjct: 519 QGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGA 578

Query: 313 RGPKGYKGEKGKRGID------------GVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP 360
           +G  G  GE G+RG D            G  G+ G  G PG+PG  G  G DG QGP G 
Sbjct: 579 QGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGS 638

Query: 361 KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA 420
            G  G  G  G++G PG  G  G  G+ GP G++G  G+PG PG  G  G  G+PG +G 
Sbjct: 639 LGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGP 698

Query: 421 PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480
           PG +G  G  GP+G  G  GPRG  G  G +G +G +G  G  G PG  G IG KG RG+
Sbjct: 699 PGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGE 758

Query: 481 EGPPGS------EGARGAPGPAGPPGDPGLMGERGEDGPAG----------NGTEGFPGF 524
            G PGS      EG +G  GP G PG PGLMGE+G+ G  G           G+ GFPGF
Sbjct: 759 VGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGF 818

Query: 525 PGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGV---KGAKGYRGPEGPQG 581
           PG  G +GA G++G  G  G +G  G  G  G       PRG     GAKG  G +GP G
Sbjct: 819 PGASGEKGARGLSGKSGPRGERGPTGPRGQRG-------PRGATGKSGAKGTSGGDGPHG 871

Query: 582 PPGHQGPPGP 591
           PPG +G PGP
Sbjct: 872 PPGERGLPGP 881



 Score =  291 bits (745), Expect = 2e-78
 Identities = 173/408 (42%), Positives = 205/408 (50%), Gaps = 72/408 (17%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGE---KGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG-- 311
            GPPGL G+ G  G  G PG PG    KG  G PG PG  G  G +G+ G+ G RGE+G  
Sbjct: 784  GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 843

Query: 312  ----SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAF 367
                 RGP+G  G+ G +G  G DG  G  G  GLPG +G  GF G +GPPGP G  G  
Sbjct: 844  GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLP 903

Query: 368  GLKGEKGEPGADGEAGRPG------------SSGPSGDEGQPGEPGPPGEKG------EA 409
            G  G++GE G  G+ G PG             +GP G+ G PG PGPPGE+G      + 
Sbjct: 904  GHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKE 963

Query: 410  GDEGNPGPDGAPGE------RGGPGERG---------------------PRGTPGTRGPR 442
            G +G+PGP GAPG+      RG PGERG                     P G+PG RG  
Sbjct: 964  GTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAA 1023

Query: 443  GDPGEAGPQGDQGREGPVGVPGD---PGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPP 499
            G  G  GP G  G +GP G  G+   PGE GPIGP G  G +GP G  G  G PG AG  
Sbjct: 1024 GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGED 1083

Query: 500  GDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDD 558
            GD G +G+ G+ G  GN G  G PG PG  G  G PG  G  G PG +G +G  G  GD+
Sbjct: 1084 GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1143

Query: 559  NND--------------IAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592
                               P G KG  G  GP GP GPPG +GP GP+
Sbjct: 1144 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPN 1191



 Score =  281 bits (719), Expect = 2e-75
 Identities = 158/346 (45%), Positives = 182/346 (52%), Gaps = 20/346 (5%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQG------MKGEKGSRGEK 310
            GPPG  G  G  G  G+ G+PGEKG  G  GR G  GPVG  G      + GE G +GE 
Sbjct: 1030 GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 1089

Query: 311  GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370
            G  G KG KG KG+ G  G  G  G +G PG  G  G PG  G QG  G KGD G  G  
Sbjct: 1090 GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFN 1149

Query: 371  GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPG---ERGGP 427
            G  G  G  G  G  G  G +GD G  G PGPPG +G AG  G  GP G PG     G P
Sbjct: 1150 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPP 1209

Query: 428  GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487
            GE+G  G  G+ G +G+PG  GP+G++G +G  G PG+P   GP GPKG  GD+GP G+ 
Sbjct: 1210 GEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEP---GPPGPKGPTGDDGPKGNP 1266

Query: 488  GARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGTKGYPGLK 546
            G  G PG  GPPG+ G  G+ G  G  G +G  G PG PG  G  G PG  G +G  G  
Sbjct: 1267 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1326

Query: 547  GDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592
            G EG  G  G        +G  GA G  G  GP GP G  G PGPD
Sbjct: 1327 GSEGRQGGKG-------AKGDPGAIGAPGKTGPVGPAGPAGKPGPD 1365



 Score =  279 bits (714), Expect = 8e-75
 Identities = 164/350 (46%), Positives = 183/350 (52%), Gaps = 26/350 (7%)

Query: 257  GPPGLRGDPGFEGERGKPGL---PGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSR 313
            GPPG RG PG +G  G PG    PG  G+ G PG PG  G VG+QG  G  G  G  G +
Sbjct: 871  GPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ 930

Query: 314  GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373
            G  G  G  G+RG  G  G  GE G   LPG  G  G  G  GPPG  G  G  GL+G  
Sbjct: 931  GAAGETGPMGERGHPGPPGPPGEQG---LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFP 987

Query: 374  GEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD------EGNPGPDGAP---GER 424
            GE G  G AG PG  G  G  G PG  G PGE+G AG        G PGP G P   GE+
Sbjct: 988  GERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEK 1047

Query: 425  GGPGER---GPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE 481
            G PGE+   GP G  G +GP G PG AGP G  G +G  G  GDPG+ G  G KG  G  
Sbjct: 1048 GVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPP 1107

Query: 482  GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTK 540
            GPPG  G  G PG AG  G+PG  G +G  G  G+ GT GF G PG  G +G PG +G K
Sbjct: 1108 GPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEK 1167

Query: 541  GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
            G  G  G  G  G PG       PRG  G  G  GP+GP G  G+ GPPG
Sbjct: 1168 GETGDVGPMGPPGPPG-------PRGPAGPNGADGPQGPPGGVGNLGPPG 1210



 Score =  279 bits (713), Expect = 1e-74
 Identities = 161/377 (42%), Positives = 189/377 (50%), Gaps = 51/377 (13%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGE------ 309
            RG PG  G PG +G  G  G  G KG+ G PG PG  GP G +G  GE+G  G       
Sbjct: 942  RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGL 1001

Query: 310  KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGL 369
            KG+ GP G  G  G  G  G  G  G +G PG PG +G PG  G +G PG KG  G  G 
Sbjct: 1002 KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGR 1061

Query: 370  KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGE 429
             G +G  G  G AG PG +G  GD+G+ G+PG  G KG  G+ G PGP G  G  G PG 
Sbjct: 1062 DGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1121

Query: 430  RGPRGTPGTRGPRGD------------------------PGEAGPQGDQGREGPVGVPGD 465
             G  G PG RGP+G                         PG +G +G+ G  GP+G PG 
Sbjct: 1122 AGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP 1181

Query: 466  PGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGD---PGLMGE---------RGEDGP 513
            PG  GP GP G  G +GPPG  G  G PG  G PG+   PG+ GE         RGE G 
Sbjct: 1182 PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGE 1241

Query: 514  AGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573
            +G      PG PG PG +G  G +G KG PG  G  G+ G PG+      PRG  GAKG 
Sbjct: 1242 SGQ-----PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEG----GPRGQDGAKGD 1292

Query: 574  RGPEGPQGPPGHQGPPG 590
            RG +G  G PG  GP G
Sbjct: 1293 RGEDGEPGQPGSPGPTG 1309



 Score =  277 bits (709), Expect = 3e-74
 Identities = 165/378 (43%), Positives = 194/378 (51%), Gaps = 45/378 (11%)

Query: 253  QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP---VGYQGMKGEKGSRGE 309
            Q   G PG +G PG  G+ G PG PG++GE G  G+ G  GP   VG QG  GE G  GE
Sbjct: 882  QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 941

Query: 310  KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPG---FDGIQGPPGPKGDPGA 366
            +G  GP G  GE+G  G  G +G KG+ G PG PG  G  G   F G +G PG  G PG 
Sbjct: 942  RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGL 1001

Query: 367  FGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGP------------PGEKGEAGDEGN 414
             G +G  G PG  G  G  G++G  G  G PG PGP            PGEKG  G  G 
Sbjct: 1002 KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGR 1061

Query: 415  ---------PGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVP-- 463
                     PGP G PG  G  G++G  G PG +G +G+ GE GP G  G  GPVG P  
Sbjct: 1062 DGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1121

Query: 464  ----GDPGEAGPIGPKGYRGDE------GPPGSEGARGAPGPAGPPGDPGLMGERGEDGP 513
                G+PG  GP G  G +GDE      GPPG  G +G PGP+G  G+ G +G  G  GP
Sbjct: 1122 AGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP 1181

Query: 514  AGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573
               G  G  G  G  G +G PG  G  G PG KG+ GE+G PG         GVKG +G 
Sbjct: 1182 P--GPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEP----GVKGPRGE 1235

Query: 574  RGPEGPQGPPGHQGPPGP 591
            RG +G  G PG  GPPGP
Sbjct: 1236 RGEKGESGQPGEPGPPGP 1253



 Score =  277 bits (708), Expect = 4e-74
 Identities = 163/387 (42%), Positives = 190/387 (49%), Gaps = 55/387 (14%)

Query: 256 RGPPGLRGDPGFEGERGKPG-------------------------------------LPG 278
           RGPPG  G PG +G  G PG                                     L G
Sbjct: 428 RGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRG 487

Query: 279 EKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMG 338
             G  G  GRPG LG  G  G+KGE G  G +G RGP+G  G  GK G  G  G  G  G
Sbjct: 488 PPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARG 547

Query: 339 YPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGE---------AGRPGSSG 389
            PG PG KG  GFDG+ G PG KG  G  G +G  G PG DGE          G PG SG
Sbjct: 548 MPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESG 607

Query: 390 PSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAG 449
           P G  G  G PG PG  G  G +G  GP G+ G +G PG  G +GTPGT+G  G  G  G
Sbjct: 608 PRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIG 667

Query: 450 PQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERG 509
           P G++G +G  G+PG PG     GP G+ G EGPPG++G +G  GP GP G PG  G +G
Sbjct: 668 PHGEKGPQGKPGLPGMPGSD---GPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKG 724

Query: 510 EDGPAG----NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPG--DDNNDIA 563
            DG  G     G +G  GFPG+ G+ G  G  G  G PG +G++G  G  G      D  
Sbjct: 725 VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG 784

Query: 564 PRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           P G+ G KG  G  G  G PG QGP G
Sbjct: 785 PPGLMGEKGKLGVPGLPGYPGRQGPKG 811



 Score =  272 bits (696), Expect = 1e-72
 Identities = 157/358 (43%), Positives = 186/358 (51%), Gaps = 25/358 (6%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            RG  G RG  G  G +G  G  G  G  G+ G PG  GP G+ G KG  G  G+ G  G 
Sbjct: 846  RGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGH 905

Query: 316  KGYKGE---KGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372
             G +GE   +GK G  G  GV G  G  G  G  G  G  G  GPPG +G PG  G +G 
Sbjct: 906  PGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 965

Query: 373  KGEPGADGEAGRPGSSGP---SGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGG--- 426
            KG+PG  G  G+ G +G     G+ G PG  G PG KG  G  G PGP G+PGERG    
Sbjct: 966  KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 1025

Query: 427  ------PGERGPRGTPGTRGPRGDPGEAGPQGDQGR---EGPVGVPGDPGEAGPIGPKGY 477
                  PG  GP+G PG  G +G PGE GP G  GR   +GPVG+PG  G  G  G  G 
Sbjct: 1026 GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGD 1085

Query: 478  RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGIN 537
            +G+ G PG +G +G  G  GPPG PG +G  G+ G A  G +G PG  G  G+ GA G  
Sbjct: 1086 KGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAA--GADGEPGARGPQGHFGAKGDE 1143

Query: 538  GTKGYPGLKGDEGEAGDPG-----DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
            GT+G+ G  G  G  G PG      +  D+ P G  G  G RGP GP G  G QGPPG
Sbjct: 1144 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG 1201



 Score =  267 bits (683), Expect = 3e-71
 Identities = 169/399 (42%), Positives = 197/399 (49%), Gaps = 60/399 (15%)

Query: 253 QPARGPPGL--RGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310
           +PA   PG+   G PG EG  G  G PG +G  G  G PG+ GP G  G+ G  G+ G  
Sbjct: 387 EPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPP 446

Query: 311 GS--------------RGPKGYKGE--------------KGKRGIDGVDGVKGEMGYPGL 342
           G+              +GP     E              +G  G  G  G  G +G PG 
Sbjct: 447 GTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGS 506

Query: 343 PGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGP 402
           PG KG  G  G QGP GP+G  G  G  G +G  GADG  G PG  G  GD G  G PG 
Sbjct: 507 PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGL 566

Query: 403 PGEKGEAGD---EGNPGPDGAPGERGGPGERGPRGTPGTRGPR------GDPGEAGPQGD 453
           PGEKG  GD   +G PGP G  GERG  GE GPRG PG  GPR      G PG  GP G 
Sbjct: 567 PGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV 626

Query: 454 QGREGPVGVPGD---PGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGE 510
           +G +GP G  G     GE GP G +G  G +G PG +GA G  G  GP G PGL G  G 
Sbjct: 627 RGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGS 686

Query: 511 DGPAGN-GTEGFPGFP------------GYPGNRGAPGINGTKGYPGLKGDEGEAGDPGD 557
           DGP G+ G EG PG              GYPG RG  G++G +G  G KG++GE G PG 
Sbjct: 687 DGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF 746

Query: 558 DNN-----DIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
             +     D    GV G++G  GPEGP+G  G  G PGP
Sbjct: 747 KGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP 785



 Score =  243 bits (621), Expect = 5e-64
 Identities = 130/276 (47%), Positives = 155/276 (56%), Gaps = 9/276 (3%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            +GP G RG+ G  G+ G+PG PG KG  GD G  G+ GPVG+ G  G  G  G +G  G 
Sbjct: 1230 KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGA 1289

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKG---SPGFDGIQGPPGPKGDPGAFGLKGE 372
            KG +GE G+ G  G  G  GE G PG  G +G   SPG +G QG  G KGDPGA G  G+
Sbjct: 1290 KGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGK 1349

Query: 373  KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGP 432
             G  G  G AG+PG  G  G  G  G+ G PG  G+AG  G  GP G PG RG  G +G 
Sbjct: 1350 TGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1409

Query: 433  RGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGD------PGEAGPIGPKGYRGDEGPPGS 486
            +G PG  G  G PGE G +GD+G  GP G PG       PG +GPIGP G  G  GP G 
Sbjct: 1410 KGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGP 1469

Query: 487  EGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFP 522
            +GA+GA GP GP G+ G+ G  G  GP G   +  P
Sbjct: 1470 KGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1505



 Score =  199 bits (507), Expect = 9e-51
 Identities = 146/399 (36%), Positives = 173/399 (43%), Gaps = 98/399 (24%)

Query: 282 EAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGI--DGVDGVKGEMGY 339
           E G+ G     GP  Y    G+     E+   GP     E    G    G  G+KGE G 
Sbjct: 331 EYGEGGTDPPEGPYDYTYGYGD--DYREETELGP-ALSAETAHSGAAAHGPRGLKGEKGE 387

Query: 340 PGLPGCKGSPGFDGIQGPPGPK------------------GDPGAFGLKGEKGEPGADGE 381
           P +      PG   ++GPPGP+                  GDPG  G  G  G PG+DG 
Sbjct: 388 PAVL----EPGML-VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGA 442

Query: 382 AGRPGSS----------------------------------------GPSGDEGQP---G 398
            G PG+S                                        GP G  G+P   G
Sbjct: 443 PGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLG 502

Query: 399 EPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREG 458
           +PG PG KGE+GD G  GP G  G  G PG+ G RG  G  G RG PG+ G +GD+G +G
Sbjct: 503 QPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDG 562

Query: 459 PVGVPGDPGE---------AGPIGPKGYRGDEGP------PGSEGARGAPGPAGPPGDPG 503
             G+PG+ G           GP G  G RGD+G       PG  G RG  GP GPPG PG
Sbjct: 563 LPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPG 622

Query: 504 LMGERGEDGPAG-------NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPG 556
             G RG DGP G        G  G PG  G PG +G PG  G  G  G KG +G+ G PG
Sbjct: 623 PPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPG 682

Query: 557 DDNNDIAP-----RGVKGAKGYRGPEGPQGPPGHQGPPG 590
              +D  P      G  G KG +GP GPQGP G+ GP G
Sbjct: 683 MPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRG 721



 Score =  199 bits (505), Expect = 1e-50
 Identities = 119/281 (42%), Positives = 140/281 (49%), Gaps = 20/281 (7%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGD---PGRPGDLGPVGYQGMKGEKGSRGEKGSR 313
            GP G  GDPG  GE G  G  G KG+ G+   PG+PG  GP G  G  G  G RG  GS 
Sbjct: 1267 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1326

Query: 314  GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373
            G +G +G KG +G  G  G  G+ G  G  G  G PG DG++G PG  G  G  G  G+ 
Sbjct: 1327 GSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQA 1386

Query: 374  GEPGADGEAGRPGSSGPSGDEGQPGEP------GPPGEKGEAGDEGNPGPDGAPGERGGP 427
            G PG  G  G PG  G +G +G+ G P      GPPGE+GE GD G PGP G+PG++G  
Sbjct: 1387 GPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEM 1446

Query: 428  GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487
            G  G  G  G  GP G PG AGP+G +G  GP          GP G KG +G  G PG  
Sbjct: 1447 GIPGASGPIGPGGPPGLPGPAGPKGAKGATGP---------GGPKGEKGVQGPPGHPGPP 1497

Query: 488  GARGAPGPAGPPGDP--GLMGERGEDGPAGNGTEGFPGFPG 526
            G    P P   P      + G R         T G PG PG
Sbjct: 1498 GEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1538



 Score =  186 bits (472), Expect = 1e-46
 Identities = 114/269 (42%), Positives = 132/269 (49%), Gaps = 27/269 (10%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS--- 312
            RG  G +GD G +GE G+PG PG  GE G PG  G  GP G  G +G +G +G KG    
Sbjct: 1284 RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGA 1343

Query: 313  ------RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366
                   GP G  G  GK G DG+ G+ G +G  G PG  G  G     GP GP G PG 
Sbjct: 1344 IGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAG---PPGPVGPPGLPGL 1400

Query: 367  ---FGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGE 423
                G KGEKG PG  G  G PG  G  GD G PG  G PG+KGE G  G  GP G  G 
Sbjct: 1401 RGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP 1460

Query: 424  RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGP-----KGYR 478
             G PG  GP+G  G  GP       GP+G++G +GP G PG PGE     P     K  R
Sbjct: 1461 PGLPGPAGPKGAKGATGP------GGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRR 1514

Query: 479  GDEGPPGSEGARGAPGPAGPPGDPGLMGE 507
              +G    +     P   G PG PG + E
Sbjct: 1515 SVDGSRLMQEDEAIP-TGGAPGSPGGLEE 1542



 Score = 31.2 bits (69), Expect = 5.2
 Identities = 13/25 (52%), Positives = 16/25 (64%)

Query: 255  ARGPPGLRGDPGFEGERGKPGLPGE 279
            A GP G +G+ G +G  G PG PGE
Sbjct: 1475 ATGPGGPKGEKGVQGPPGHPGPPGE 1499


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  303 bits (775), Expect = 7e-82
 Identities = 166/357 (46%), Positives = 196/357 (54%), Gaps = 29/357 (8%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            G PG+ G  G  G RG+ G+ G+KG+ G  G PG  GP+G QG+ G  G +GE G  GP 
Sbjct: 1171 GAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPM 1230

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGC------KGSPGFDGIQGPPGPKGDPGAFGLK 370
            G  G  G RG  G +G  G  G PG  G       KG PG  G  GPPG  G  G  G +
Sbjct: 1231 GPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGER 1290

Query: 371  GEKGEPGADGEAGRPGSSGPSGDEGQ---------PGEPGPPGEKGEAGDEG---NPGPD 418
            GEKGE G  G AG PG+ GP GD+G          PG+PGPPGE G AG +G   + G D
Sbjct: 1291 GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGED 1350

Query: 419  GAPGERGGPG---ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475
            G PG+ G PG   E GP G PG RGP G  G  G QG++G +G  G  G PG+ GP+GP+
Sbjct: 1351 GDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQ 1410

Query: 476  GYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAP 534
            G     G PG EG RG PGP G  G PG  G+ G  GP G  G  G  G PG  G +G P
Sbjct: 1411 G---PAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHP 1467

Query: 535  GINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
            G+ G  G PG +G++G+ G PG   +     G KG  G  GP GP GPPG  G PGP
Sbjct: 1468 GLIGLIGPPGEQGEKGDRGLPGTQGSP----GAKGDGGIPGPAGPLGPPGPPGLPGP 1520



 Score =  296 bits (758), Expect = 7e-80
 Identities = 170/376 (45%), Positives = 199/376 (52%), Gaps = 47/376 (12%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            +G PGL G PG +G  G PG  G+ GE G  G PG  GP+GY G +G KG+ G +G +G 
Sbjct: 729  QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 788

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375
            KG KGE G  G  G  G+KG+ G  G  G +G  G +G +G  GP GDPG  G  GEKG+
Sbjct: 789  KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 848

Query: 376  PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP---------GPDGAPGERGG 426
             G  G  G PG  GP G  G PG PG  GEKG  G  G P         GP G+ G RG 
Sbjct: 849  LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 908

Query: 427  PGERGPRGTPGTRGPRGDPGEAGPQGDQGR---EGPVGVPGDP----------------- 466
             G+ GP+GT G  GP G PGE GPQG QG     GP G PG P                 
Sbjct: 909  TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGF 968

Query: 467  -GEAGPIGPKGYRGDEGPPGSE---GARGAPGPAGPPGDPGLMGERGEDGPAG------- 515
             G+ GP GP G  G +GP G     G RG PGP GPPG+ GL G  G++G  G       
Sbjct: 969  QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGI 1028

Query: 516  NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRG 575
            +G +G  G  G+PG RG P   G +G PGLKG EG  G PG     +   G +G+ G  G
Sbjct: 1029 SGKDGPAGLRGFPGERGLP---GAQGAPGLKGGEGPQGPPG----PVGSPGERGSAGTAG 1081

Query: 576  PEGPQGPPGHQGPPGP 591
            P G  G PG QGPPGP
Sbjct: 1082 PIGLPGRPGPQGPPGP 1097



 Score =  295 bits (754), Expect = 2e-79
 Identities = 163/357 (45%), Positives = 197/357 (55%), Gaps = 21/357 (5%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            G PG RG+ GF+G+ G PG  G  G  G  G  G +G  G+ G  G  G +G  G+ G +
Sbjct: 958  GHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKE 1017

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPG---LPGCKGSPGF---DGIQGPPGPKGDPGAFGLK 370
            G KG+ G +GI G DG  G  G+PG   LPG +G+PG    +G QGPPGP G PG  G  
Sbjct: 1018 GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA 1077

Query: 371  GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGN---PGPDGAPGERGGP 427
            G  G  G  G  G  G  GP+G++G PGE GP G  G  G +G    PGP G  G  G  
Sbjct: 1078 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGED 1137

Query: 428  GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487
            G++G  G PG +G +GD GE GP G  G +GPVG PG  G  G  GP+G +G  G  G E
Sbjct: 1138 GDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDE 1197

Query: 488  GARGAPGPAGP------PGDPGLMGERGEDGPAG----NGTEGFPGFPGYPGNRGAPGIN 537
            GARG PGP GP      PG PG  GE G+ GP G     G  G  G  G  G +G PG  
Sbjct: 1198 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV 1257

Query: 538  GTKGYPGLKGDEGEAGDPG--DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592
            G+ G  G KG+ GEAG+PG   +     P+G +G KG  GP G  GPPG +GPPG D
Sbjct: 1258 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDD 1314



 Score =  294 bits (752), Expect = 3e-79
 Identities = 157/351 (44%), Positives = 190/351 (54%), Gaps = 17/351 (4%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
           G PG RG PG +G RG PG PG KG+ G  G PG  G  G++G +G +G  G  G  G +
Sbjct: 586 GKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMR 645

Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD---------PGAF 367
           G  GE G RG+ G  G +G +G  G PG  G PG  G+ GPPGPKG+         PG  
Sbjct: 646 GEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQ 705

Query: 368 GLKGEKGEPGADGEAGRPGSSGPSGDEGQ---PGEPGP---PGEKGEAGDEGNPGPDGAP 421
           G  G +G PG  G  G PG  GP G  G    PG  GP   PG++G++G++G  GP G  
Sbjct: 706 GNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQ 765

Query: 422 GERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE 481
           G  G PG RG +G  G RG +G  GE G  G  G +G +G+ GD GE G IGP+G  G E
Sbjct: 766 GPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPE 825

Query: 482 GPPGSEGARGAPGPAGPPGDPGLMGERGEDG-PAGNGTEGFPGFPGYPGNRGAPGINGTK 540
           GP G  G  G PGP+G  G+ G +G  G  G P   G +G  GFPG+PG  G  G  G  
Sbjct: 826 GPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA 885

Query: 541 GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
           G PG +G  G  G P        P G  G KG  G +GP GPPG +GP GP
Sbjct: 886 GKPGPRGQRGPTG-PRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGP 935



 Score =  291 bits (744), Expect = 3e-78
 Identities = 176/376 (46%), Positives = 204/376 (54%), Gaps = 44/376 (11%)

Query: 255  ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGR---PGDLGPVGYQGMKGEKGSRGEKG 311
            A+G PGL+G  G +G  G  G PGE+G AG  G    PG  GP G  G  GEKG+ GEKG
Sbjct: 1049 AQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG 1108

Query: 312  SRGPKGYKGEKGKRGI---------DGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKG 362
             +GP G  G +G  G+          G DG KGE+G PG  G KG  G +G  GPPG +G
Sbjct: 1109 PQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQG 1168

Query: 363  DPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE---------PGPPGEKGEAGDEG 413
              GA G+ G  GEPG  G+ G  G  G  G  G PG          PGPPGEKGE GD G
Sbjct: 1169 PVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVG 1228

Query: 414  NPGPDGAPGERG--GP-GERGPRGTPGT------RGPRGDPGEA---GPQGDQGREGPVG 461
              GP G PG RG  GP G  GP+G PG+       G +G+PGEA   GP G+ G  GP G
Sbjct: 1229 PMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKG 1288

Query: 462  VPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGE---RGEDGPAGN-G 517
              G+ GEAGP G  G  G +GPPG +G +G PGP G PGDPG  GE    G+DG  G+ G
Sbjct: 1289 ERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKG 1348

Query: 518  TEGFPGFPGYP---GNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYR 574
             +G PG PG P   G  G PG  G +G PG  G EG  G+ G         G +G  G  
Sbjct: 1349 EDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE----AGAEGPPGKT 1404

Query: 575  GPEGPQGPPGHQGPPG 590
            GP GPQGP G  GP G
Sbjct: 1405 GPVGPQGPAGKPGPEG 1420



 Score =  289 bits (739), Expect = 1e-77
 Identities = 162/348 (46%), Positives = 187/348 (53%), Gaps = 20/348 (5%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLG---PVGYQGMKGEKGSRGEKGSR 313
            G PG +G PG  GE+G PG  G +G AG  G  G +G   P G  G  GE G +GE G  
Sbjct: 1087 GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEP 1146

Query: 314  GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373
            G KG KG+KG+ G  G  G++G +G PG+ G  G PG  G QG  G KGD GA G  G  
Sbjct: 1147 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPP 1206

Query: 374  GEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPR 433
            G  G  G  G PG  G +GD G  G PGPPG +G  G  G  GP G PG  G  G  G +
Sbjct: 1207 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1266

Query: 434  GTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAP 493
            G PG  G  G PGEAG  G +G  G  G  G PG AGP G KG  GD+GP G+ G  G P
Sbjct: 1267 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFP 1326

Query: 494  GPAGPPGDP------GLMGERGEDGPAGN----GTEGFPGFPGYPGNRGAPGINGTKGYP 543
            G  GPPG+P      G+ G++GEDG  G     G  G  G PG PG RG PG  G +G  
Sbjct: 1327 GDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ 1386

Query: 544  GLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
            G KG +GEAG  G       P G  G  G +GP G  GP G +G PGP
Sbjct: 1387 GEKGAKGEAGAEG-------PPGKTGPVGPQGPAGKPGPEGLRGIPGP 1427



 Score =  288 bits (737), Expect = 2e-77
 Identities = 166/364 (45%), Positives = 195/364 (53%), Gaps = 31/364 (8%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP------VGYQGMKGEKGSRGE 309
            RGP G RG  G  G  GKPG  G  G  G PG PG+ GP      VG+ G KG  G  G+
Sbjct: 894  RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGK 953

Query: 310  KGSRGPKGYKGE---KGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366
             G  G  G +GE   +GK G  G  GV G  G  G  G  G  G  G  GPPG +G PGA
Sbjct: 954  DGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGA 1013

Query: 367  FGLKGEKGEPGADGEAGRPGSSGPSG---DEGQPGEPGPPGEKGEAGDEGNPGPDGAPGE 423
             G +G KG+PG  G +G+ G +G  G   + G PG  G PG KG  G +G PGP G+PGE
Sbjct: 1014 AGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGE 1073

Query: 424  RGG---------PGERGPRGTPGTRGPRGDPGEAGPQGDQGR---EGPVGVPGDPGEAGP 471
            RG          PG  GP+G PG  G +G PGE GPQG  GR   +GPVG+PG  G AG 
Sbjct: 1074 RGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1133

Query: 472  IGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNR 531
             G  G +G+ G PG +G++G  G  GPPG PGL G  G  G AG   +G PG  G  G  
Sbjct: 1134 PGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG--DGEPGPRGQQGMF 1191

Query: 532  GAPGINGTKGYPGLKGDEGEAGDPG-----DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQ 586
            G  G  G +G+PG  G  G  G PG      +N D+ P G  G  G RGP+GP G  G Q
Sbjct: 1192 GQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1251

Query: 587  GPPG 590
            GPPG
Sbjct: 1252 GPPG 1255



 Score =  286 bits (732), Expect = 7e-77
 Identities = 170/393 (43%), Positives = 194/393 (49%), Gaps = 63/393 (16%)

Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
           RGPPG  G  G  G  G PG  G KGE+GDPG  G  G  G  G  G+ G RG  G+ G 
Sbjct: 540 RGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGG 599

Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375
           +G  GE G +G  G DG+      PGLPG KG  G  G QGPPGP GD G  G  GE G 
Sbjct: 600 RGMPGEPGAKGDRGFDGL------PGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP 653

Query: 376 PGADGEAGRPGSSGPSGDEGQPGEP------GPPGEKGEAGDEGNPGP---DGAPGERGG 426
            G  GEAG  G  GP G  G PG+P      GPPG KG  G +G PGP    G PG +G 
Sbjct: 654 RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 713

Query: 427 PGERGPRGTPGTRGPRGDPGEA------GPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480
           PG +GP G PG +GP+G PG A      GP G  G+EG  G  G  G  GP GP GY G 
Sbjct: 714 PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGP 773

Query: 481 EGPPGSEGARGAPGPAGPPGDPGL------------------MGERGEDGPAG------- 515
            G  G++G RG  G  G  G+ G                   +G RGEDGP G       
Sbjct: 774 RGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP 833

Query: 516 ------------NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGE---AGDPG--DD 558
                        G  G PG PGYPG +G  G  G  G+PG  G++G    AG PG    
Sbjct: 834 TGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQ 893

Query: 559 NNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
                PRG +GA+G  G  GP+G  G  GPPGP
Sbjct: 894 RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGP 926



 Score =  284 bits (727), Expect = 3e-76
 Identities = 157/346 (45%), Positives = 187/346 (54%), Gaps = 21/346 (6%)

Query: 255  ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314
            A G  GL+G  G +GE G PG  G+ G  GD G  G +GP G  G +G KG  G  G  G
Sbjct: 779  ADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 838

Query: 315  PKGYKGEKGKRGIDGVDGV------KGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFG 368
            P G  GEKGK G+ G+ G       KG  G+PG PG  G  G  G+ G PGP+G  G  G
Sbjct: 839  PSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTG 898

Query: 369  LKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPG 428
             +G +G   A G  G+PG  G SG +G PG   PPGE+G  G +   GP G PG +G PG
Sbjct: 899  PRGSRG---ARGPTGKPGPKGTSGGDGPPG---PPGERGPQGPQ---GPVGFPGPKGPPG 949

Query: 429  ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEG 488
              G  G PG  G RG+ G  G  G  G  G VG  G  GE GPIG +G+ G  GPPG +G
Sbjct: 950  PPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQG 1009

Query: 489  ARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGD 548
              GA G  G  GDPG  G  G+DGPA  G  GFPG  G PG +GAPG+ G +G  G  G 
Sbjct: 1010 LPGAAGKEGAKGDPGPQGISGKDGPA--GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGP 1067

Query: 549  EGEAGDPGDDNNDIAPRGVKGAKGYRGPEGP---QGPPGHQGPPGP 591
             G  G+ G       P G+ G  G +GP GP   +G PG +GP GP
Sbjct: 1068 VGSPGERGSAGT-AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGP 1112



 Score =  284 bits (726), Expect = 3e-76
 Identities = 157/342 (45%), Positives = 188/342 (54%), Gaps = 13/342 (3%)

Query: 257  GPPGLRGDPGFEGERGKPGLPG------EKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310
            G PG  G  G +G+ G PGLPG       KG  G PG PG  G  G +G+ G+ G RG++
Sbjct: 835  GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 894

Query: 311  GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370
            G  GP+G +G +G  G  G  G  G  G PG PG +G  G  G  G PGPKG PG  G  
Sbjct: 895  GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 954

Query: 371  GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGER 430
            G  G PG  GE G  G +GP G  G  G  GP GE G  G+ G+PGP G PGE+G PG  
Sbjct: 955  GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 1014

Query: 431  GPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGAR 490
            G  G  G  GP+G  G+ GP G +G  G  G+PG  G  G  G +G +G  GP GS G R
Sbjct: 1015 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1074

Query: 491  GAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEG 550
            G+ G AGP G PG  G +G  GPAG       G PG  G +G  G +G +G  GL G  G
Sbjct: 1075 GSAGTAGPIGLPGRPGPQGPPGPAGE-----KGAPGEKGPQGPAGRDGVQGPVGLPGPAG 1129

Query: 551  EAGDPGDDNN--DIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
             AG PG+D +  +I   G KG+KG +G  GP GPPG QGP G
Sbjct: 1130 PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG 1171



 Score =  284 bits (726), Expect = 3e-76
 Identities = 164/365 (44%), Positives = 189/365 (51%), Gaps = 41/365 (11%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGD------PGRPGDLGPVGYQGMKGEKGSRGEK 310
            G  G  G PG  G +G PG PGEKGE GD      PG PG  GP G  G  G +G  G  
Sbjct: 1198 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV 1257

Query: 311  GSRGPKGYKGEKGKRG---------IDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361
            GS G  G KGE G+ G         + G  G +GE G  G PG  G PG  G  G  GPK
Sbjct: 1258 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK 1317

Query: 362  GDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP---GPD 418
            G+PG  G  G+ G PG  G AG+ G  G  G++G PG+PGPPG  GEAG  G P   GP 
Sbjct: 1318 GNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPP 1377

Query: 419  GAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYR 478
            GA G  G  GE+G +G  G  GP G  G  GPQG  G+ GP G+ G PG           
Sbjct: 1378 GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV--------- 1428

Query: 479  GDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGIN 537
            G++G PG+ G  G PGP GPPG PGL G+ G  G  G+ G  G  G PG  G +G  G+ 
Sbjct: 1429 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1488

Query: 538  GTKGYPGLKGD------EGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQ------GPPGH 585
            GT+G PG KGD       G  G PG       P+G KG KG  GP G +      GPPG 
Sbjct: 1489 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLP-GPQGPKGNKGSTGPAGQKGDSGLPGPPGS 1547

Query: 586  QGPPG 590
             GPPG
Sbjct: 1548 PGPPG 1552



 Score =  282 bits (722), Expect = 1e-75
 Identities = 168/378 (44%), Positives = 193/378 (51%), Gaps = 44/378 (11%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            G  G  G PG  GE+G PG  G++G  GDPG  G  G  G  G++G  G RG  G++G  
Sbjct: 994  GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1053

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376
            G KG +G +G  G  G  GE G  G  G  G PG  G QGPPGP G+ GA G KG +G  
Sbjct: 1054 GLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPA 1113

Query: 377  GAD---------GEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPD------GAP 421
            G D         G AG  GS G  GD+G+ GEPG  G KG+ G+ G PGP       GAP
Sbjct: 1114 GRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAP 1173

Query: 422  GERGGPGERGPRGTPGTRGPRGD------------------PGEAGPQGDQGREGPVGVP 463
            G  GG GE GPRG  G  G +GD                  PG  G +G+ G  GP+G P
Sbjct: 1174 GIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1233

Query: 464  GDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGD---PGLMGERGEDGPAG----N 516
            G PG  GP GP G  G +GPPGS G+ G  G  G PG+   PG  GE G  GP G     
Sbjct: 1234 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1293

Query: 517  GTEGFPGFPGYPGNRGAPGINGTKGYP---GLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573
            G  G PG  G PG +G PG +G KG P   G  GD G  G+PG    D    G KG  G 
Sbjct: 1294 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQD-GVGGDKGEDGD 1352

Query: 574  RGPEGPQGPPGHQGPPGP 591
             G  GP GP G  GPPGP
Sbjct: 1353 PGQPGPPGPSGEAGPPGP 1370



 Score =  281 bits (720), Expect = 2e-75
 Identities = 165/374 (44%), Positives = 196/374 (52%), Gaps = 41/374 (10%)

Query: 257  GPPGLRGDPG---FEGERGKPGLPGEKGEAGDPGR---PGDLGPVGYQGMKGEKGSRGEK 310
            GPPG +G+PG     G +G  G PGEKG  G PG    PG  GP G+ G +G+ G +G  
Sbjct: 700  GPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL 759

Query: 311  GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370
            G  GP+G  G  G RG+ G DGV+G  G  G  G  G PGF G  G  G +G+ G  G +
Sbjct: 760  GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 819

Query: 371  GEKGEPGADGEAGRPGSSGPSGDEGQ------PGEPGPPGEKGEAGDEGNPGPDGAPGER 424
            GE G  G  G AG  G  GPSG  G+      PG PG PG +G  G  G PG  GA GE+
Sbjct: 820  GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 879

Query: 425  G--------GP-GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475
            G        GP G+RGP G  G+RG RG  G+ GP+G  G +GP G PG+ G  GP GP 
Sbjct: 880  GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPV 939

Query: 476  GYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-------------NGTEGFP 522
            G+ G +GPPG  G  G PG  G  G+ G  G+ G  GP G              G  G P
Sbjct: 940  GFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHP 999

Query: 523  GFPGYPGNRGAPGI---NGTKGYP---GLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGP 576
            G PG PG +G PG     G KG P   G+ G +G AG  G       P G +GA G +G 
Sbjct: 1000 GPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLP-GAQGAPGLKGG 1058

Query: 577  EGPQGPPGHQGPPG 590
            EGPQGPPG  G PG
Sbjct: 1059 EGPQGPPGPVGSPG 1072



 Score =  278 bits (710), Expect = 2e-74
 Identities = 159/350 (45%), Positives = 190/350 (54%), Gaps = 23/350 (6%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
           G PGL GD G  GERG  G PG  G+ G  G  G++GP   +G+ GE G RG  G RG  
Sbjct: 616 GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP---RGLPGEAGPRGLLGPRGTP 672

Query: 317 GYKGEKGKRGIDGVDGVKGEMG---YPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373
           G  G+ G  G+DG  G KG MG    PG PG +G+PG  G+ GP GP G PG  G +G+ 
Sbjct: 673 GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP 732

Query: 374 GE---PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGER 430
           G    PGADG  G PG  G SG++G  G PGP G  G  G  G  G DG  G +G  GE+
Sbjct: 733 GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK 792

Query: 431 GPRGTPG------TRGPRGDPGEAGPQGDQGREGP---VGVPGDPGEAGPIGPKGYRGDE 481
           G  G PG       +G RG+ G+ GP+G+ G EGP    G  GDPG +G  G KG  G  
Sbjct: 793 GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP 852

Query: 482 GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTK 540
           G PG  G +G  G  G PG PG  GE+G  G AG  G  G  G  G  G+RGA G  G  
Sbjct: 853 GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKP 912

Query: 541 GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           G  G  G +G  G PG+      P+G +G  G+ GP+GP GPPG  G PG
Sbjct: 913 GPKGTSGGDGPPGPPGER----GPQGPQGPVGFPGPKGPPGPPGKDGLPG 958



 Score =  277 bits (709), Expect = 3e-74
 Identities = 157/344 (45%), Positives = 182/344 (52%), Gaps = 21/344 (6%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            RGP G +G  GF G +G PG PG+ G    PG PG  G  G+QG  G  G  G  G +GP
Sbjct: 930  RGPQGPQGPVGFPGPKGPPGPPGKDGL---PGHPGQRGETGFQGKTGPPGPGGVVGPQGP 986

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375
             G  G  G+RG  G  G  GE G PG  G +G+ G  G QG  G  G  G  G  GE+G 
Sbjct: 987  TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL 1046

Query: 376  PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD---EGNPGPDGAPG---ERGGPGE 429
            PGA G  G  G  GP G  G  G PG  G  G AG     G PGP G PG   E+G PGE
Sbjct: 1047 PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1106

Query: 430  RGPRGTPG---TRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGS 486
            +GP+G  G    +GP G PG AGP G  G +G  G  G+PG+ G  G KG  G  GPPG 
Sbjct: 1107 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1166

Query: 487  EGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLK 546
            +G  GAPG AG  G+PG  G++G  G  G+  EG  GFPG PG  G  G+ G  G  G  
Sbjct: 1167 QGPVGAPGIAGGDGEPGPRGQQGMFGQKGD--EGARGFPGPPGPIGLQGLPGPPGEKGEN 1224

Query: 547  GDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
            GD G  G PG       P G +G +G  G +GPQGPPG  G  G
Sbjct: 1225 GDVGPMGPPG-------PPGPRGPQGPNGADGPQGPPGSVGSVG 1261



 Score =  276 bits (705), Expect = 9e-74
 Identities = 161/369 (43%), Positives = 187/369 (50%), Gaps = 36/369 (9%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            RG PG +G PG +G  G  G PG  G  G+ G  G  GP+G   + G  G +G  G  G 
Sbjct: 1044 RGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIG---LPGRPGPQGPPGPAGE 1100

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGP---PGPKGDPGAFGLKGE 372
            KG  GEKG +G  G DGV+G +G PG  G  GSPG DG +G    PG KG  G  G  G 
Sbjct: 1101 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP 1160

Query: 373  KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGP 432
             G PG  G  G PG +G  G+ G  G+ G  G+KG+ G  G PGP G  G +G PG  G 
Sbjct: 1161 PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1220

Query: 433  RGTPGTRGPRGDPGEAGPQGDQ---GREGPVGVP------------GDPGEAGPIGPKGY 477
            +G  G  GP G PG  GP+G Q   G +GP G P            G+PGEAG  GP G 
Sbjct: 1221 KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1280

Query: 478  RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGI 536
             G  GP G  G +G  GP G  G PG  G  G+DGP GN G  GFPG PG PG  G  G 
Sbjct: 1281 AGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQ 1340

Query: 537  NGT---------KGYPGLKGDEGEAGDPGDDNNDIAP-----RGVKGAKGYRGPEGPQGP 582
            +G           G PG  G  GEAG PG       P      G +G KG +G  G +GP
Sbjct: 1341 DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP 1400

Query: 583  PGHQGPPGP 591
            PG  GP GP
Sbjct: 1401 PGKTGPVGP 1409



 Score =  275 bits (704), Expect = 1e-73
 Identities = 156/351 (44%), Positives = 182/351 (51%), Gaps = 30/351 (8%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            RG PG  G PG  G  G PG  G  G  G+PG PG  G  G QG+ G +G  G  G +GP
Sbjct: 669  RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 728

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGL------ 369
            +G  G  G  G DG  G  G+ G  G  G  G PG  G  G PGP+G  GA G+      
Sbjct: 729  QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 788

Query: 370  KGEKGE---PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGG 426
            KGEKGE   PG  G+ G  G  G  G  G  GE GP G KG AG  G+PGP G  GE+G 
Sbjct: 789  KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 848

Query: 427  PGERGPRGTPGTRGPRGD---PGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGP 483
             G  G  G PG +GP+G    PG  G  G++G  G  G PG  G+ GP GP+G RG  GP
Sbjct: 849  LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 908

Query: 484  PGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYP 543
             G  G +G  G  GPPG PG  G +G  GP         GFPG  G  G PG +G  G+P
Sbjct: 909  TGKPGPKGTSGGDGPPGPPGERGPQGPQGPV--------GFPGPKGPPGPPGKDGLPGHP 960

Query: 544  GLKGD---EGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
            G +G+   +G+ G PG       P GV G +G  G  GP G  GH GPPGP
Sbjct: 961  GQRGETGFQGKTGPPG-------PGGVVGPQGPTGETGPIGERGHPGPPGP 1004



 Score =  266 bits (681), Expect = 6e-71
 Identities = 165/398 (41%), Positives = 193/398 (48%), Gaps = 59/398 (14%)

Query: 253 QPARGPPGL--RGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310
           +PA   PG+   G PG  G  G  G PG +G  G PG PGD GP G  G+ G  G  G  
Sbjct: 442 EPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPP 501

Query: 311 GSR-------GPKGYKGE--------------------KGKRGIDGVDGVKGEMGYPGLP 343
           G+        G  G KG                     +G  G  G+ G  G +G PG  
Sbjct: 502 GTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSS 561

Query: 344 GCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPP 403
           G KG  G  G QGP G +G PG  G  G++G PGADG  G PG  G  GD G  G PG P
Sbjct: 562 GAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLP 621

Query: 404 GEKGEAGDEGNPGPDGAPGE---RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPV 460
           G+KG  G+ G  GP G PG+   RG  GE GPRG PG  GPRG  G  G  G  G+ G  
Sbjct: 622 GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 681

Query: 461 GVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTE 519
           GV G PG  G +GP+G  G  G  G+ G +G PGP GP G PG  G +G+ G AG  G +
Sbjct: 682 GVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 741

Query: 520 GFPGFP---------------------GYPGNRGAPGINGTKGYPGLKGDEGEAGDPG-- 556
           G PG P                     GYPG RG  G +G +G  G KG++GE G PG  
Sbjct: 742 GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 801

Query: 557 DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGP---PGP 591
            D      RG  G  G RG +GP+GP G  GP   PGP
Sbjct: 802 GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 839



 Score =  246 bits (629), Expect = 6e-65
 Identities = 139/295 (47%), Positives = 167/295 (56%), Gaps = 14/295 (4%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGE---KGSRGEKGS 312
            +G PG  G+PG  GE G  G  GE+GE G+ G PG  GP G +G  G+   KG+ G  G 
Sbjct: 1266 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1325

Query: 313  RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372
             G  G  GE G  G DGV G KGE G PG PG  G  G  G  GPPG +G PGA G +G 
Sbjct: 1326 PGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGR 1385

Query: 373  KGEPGADGEAGR---PGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGE 429
            +GE GA GEAG    PG +GP G +G  G+PGP G +G  G  G  G  GA G+ G PG 
Sbjct: 1386 QGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGP 1445

Query: 430  RGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGA 489
             GP G PG +G   DPG    +G++G  G +G+ G PGE G  G +G  G +G PG++G 
Sbjct: 1446 MGPPGLPGLKG---DPGS---KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGD 1499

Query: 490  RGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPG 544
             G PGPAGP G PG  G  G  GP GN  +G  G  G  G+ G PG  G+ G PG
Sbjct: 1500 GGIPGPAGPLGPPGPPGLPGPQGPKGN--KGSTGPAGQKGDSGLPGPPGSPGPPG 1552



 Score =  225 bits (573), Expect = 2e-58
 Identities = 118/255 (46%), Positives = 138/255 (54%), Gaps = 9/255 (3%)

Query: 255  ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGE----- 309
            A GPPG +G PG +G +G PG  G  G+ G PG PG  G  G  G KGE G  G+     
Sbjct: 1301 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1360

Query: 310  -KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFG 368
              G  GP G  G++G  G  G +G +GE G  G  G +G PG  G  GP GP G PG  G
Sbjct: 1361 PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEG 1420

Query: 369  LKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPG 428
            L+G  G  G  G  G  G  GP G  G PG PG  G+ G  G++G+PG  G  G  G  G
Sbjct: 1421 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG 1480

Query: 429  ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEG 488
            E+G RG PGT   +G PG  G  G  G  GP+G PG PG  GP GPKG +G  GP G +G
Sbjct: 1481 EKGDRGLPGT---QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG 1537

Query: 489  ARGAPGPAGPPGDPG 503
              G PGP G PG PG
Sbjct: 1538 DSGLPGPPGSPGPPG 1552



 Score =  213 bits (541), Expect = 1e-54
 Identities = 151/380 (39%), Positives = 175/380 (46%), Gaps = 70/380 (18%)

Query: 273 KPGLPGEKGEAGDPGRPGDLG----PVGYQGMKGEKGSRGE----------KGSRGPKGY 318
           KP  P    E   PG P +       +   G  GEKG +GE          +G  GP G 
Sbjct: 404 KPTSP--PNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGP 461

Query: 319 KGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD-PGAFGLKGEKGEPG 377
            G  G  G+ G  G  G+ G  G PG  G PG DG+ GPPG     P  +G  G KG   
Sbjct: 462 AGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTI 521

Query: 378 ADGEA--------------GRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGE 423
           +  EA              G PG  G +G  G  G PG  G KGE+GD G  GP G  G 
Sbjct: 522 SAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGP 581

Query: 424 RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGP 483
            G  G+ G RG PG  G RG PGE G +GD+G +G  G+PGD G       +G RG +GP
Sbjct: 582 PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGH------RGERGPQGP 635

Query: 484 PGSE------------GARGAPGPAGP------------PGDPGLMGERGEDGPAGN-GT 518
           PG              G RG PG AGP            PG PG+ G  G  GP GN G 
Sbjct: 636 PGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGP 695

Query: 519 EGFPGFPGY---PGNRGAPGINGTKGYPGLKGDEGE---AGDPGDDNNDIAP--RGVKGA 570
           +G PG PG    PG +G PG  G  G PG KG +G+   AG PG D     P   G  G 
Sbjct: 696 QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGE 755

Query: 571 KGYRGPEGPQGPPGHQGPPG 590
           KG  GP GPQGP G+ GP G
Sbjct: 756 KGALGPPGPQGPIGYPGPRG 775



 Score =  194 bits (493), Expect = 4e-49
 Identities = 107/224 (47%), Positives = 126/224 (56%), Gaps = 21/224 (9%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP---VGYQGMKGEKGSRGEKGSR 313
            G  G+ GD G +G+ G+PG PG  GEAG PG PG  GP    G +G +GEKG++GE G+ 
Sbjct: 1339 GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAE 1398

Query: 314  GPKGY------KGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAF 367
            GP G       +G  GK G +G+ G+ G +G  GLPG  G    DG  GP GP G PG  
Sbjct: 1399 GPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ---DGPPGPMGPPGLPGLK 1455

Query: 368  ---GLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGER 424
               G KGEKG PG  G  G PG  G  GD G PG  G PG KG+ G  G  GP G PG  
Sbjct: 1456 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP 1515

Query: 425  GGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGE 468
            G PG +GP+G  G+ GP      AG +GD G  GP G PG PGE
Sbjct: 1516 GLPGPQGPKGNKGSTGP------AGQKGDSGLPGPPGSPGPPGE 1553



 Score =  157 bits (398), Expect = 4e-38
 Identities = 99/238 (41%), Positives = 114/238 (47%), Gaps = 31/238 (13%)

Query: 365 GAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE--PGPPGEKGEAGDEGNPGPDGAPG 422
           GA+G KG+KGEP                   +PG    GPPG  G AG  G PG  G  G
Sbjct: 432 GAYGEKGQKGEPAVV----------------EPGMLVEGPPGPAGPAGIMGPPGLQGPTG 475

Query: 423 ERGGPGERGPRGTPGTRGPRGDPGEAGPQ-------GDQGREGPVGVPGDPGEAGPIGPK 475
             G PG+RGP G PG  G  G PG  G         G  G +GP  +     +A  I  +
Sbjct: 476 PPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPT-ISAQEAQAQAILQQ 534

Query: 476 GYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAP 534
                 GPPG  G  G PGP G PG  G  GE G+ GP G  G +G PG  G PG RG P
Sbjct: 535 ARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRP 594

Query: 535 GINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592
           G +G +G PG   + G  GD G D     P G KG +G RGP+GP GPPG  G  G D
Sbjct: 595 GADGGRGMPG---EPGAKGDRGFDGLPGLP-GDKGHRGERGPQGPPGPPGDDGMRGED 648



 Score =  103 bits (258), Expect = 6e-22
 Identities = 61/141 (43%), Positives = 73/141 (51%), Gaps = 24/141 (17%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            GPPG  G PG  G +G PG    KGE G PG  G +GP G QG KG++G  G +GS    
Sbjct: 1441 GPPGPMGPPGLPGLKGDPG---SKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGS---- 1493

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376
                           G KG+ G PG  G  G PG  G+ GP GPKG+ G+ G  G+KG+ 
Sbjct: 1494 --------------PGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDS 1539

Query: 377  GADGEAGRPGSSGPSGDEGQP 397
            G  G    PGS GP G+  QP
Sbjct: 1540 GLPGP---PGSPGPPGEVIQP 1557


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  303 bits (775), Expect = 7e-82
 Identities = 166/357 (46%), Positives = 196/357 (54%), Gaps = 29/357 (8%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            G PG+ G  G  G RG+ G+ G+KG+ G  G PG  GP+G QG+ G  G +GE G  GP 
Sbjct: 1120 GAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPM 1179

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGC------KGSPGFDGIQGPPGPKGDPGAFGLK 370
            G  G  G RG  G +G  G  G PG  G       KG PG  G  GPPG  G  G  G +
Sbjct: 1180 GPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGER 1239

Query: 371  GEKGEPGADGEAGRPGSSGPSGDEGQ---------PGEPGPPGEKGEAGDEG---NPGPD 418
            GEKGE G  G AG PG+ GP GD+G          PG+PGPPGE G AG +G   + G D
Sbjct: 1240 GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGED 1299

Query: 419  GAPGERGGPG---ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475
            G PG+ G PG   E GP G PG RGP G  G  G QG++G +G  G  G PG+ GP+GP+
Sbjct: 1300 GDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQ 1359

Query: 476  GYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAP 534
            G     G PG EG RG PGP G  G PG  G+ G  GP G  G  G  G PG  G +G P
Sbjct: 1360 G---PAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHP 1416

Query: 535  GINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
            G+ G  G PG +G++G+ G PG   +     G KG  G  GP GP GPPG  G PGP
Sbjct: 1417 GLIGLIGPPGEQGEKGDRGLPGTQGSP----GAKGDGGIPGPAGPLGPPGPPGLPGP 1469



 Score =  296 bits (758), Expect = 7e-80
 Identities = 170/376 (45%), Positives = 199/376 (52%), Gaps = 47/376 (12%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            +G PGL G PG +G  G PG  G+ GE G  G PG  GP+GY G +G KG+ G +G +G 
Sbjct: 678  QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 737

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375
            KG KGE G  G  G  G+KG+ G  G  G +G  G +G +G  GP GDPG  G  GEKG+
Sbjct: 738  KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 797

Query: 376  PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP---------GPDGAPGERGG 426
             G  G  G PG  GP G  G PG PG  GEKG  G  G P         GP G+ G RG 
Sbjct: 798  LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 857

Query: 427  PGERGPRGTPGTRGPRGDPGEAGPQGDQGR---EGPVGVPGDP----------------- 466
             G+ GP+GT G  GP G PGE GPQG QG     GP G PG P                 
Sbjct: 858  TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGF 917

Query: 467  -GEAGPIGPKGYRGDEGPPGSE---GARGAPGPAGPPGDPGLMGERGEDGPAG------- 515
             G+ GP GP G  G +GP G     G RG PGP GPPG+ GL G  G++G  G       
Sbjct: 918  QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGI 977

Query: 516  NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRG 575
            +G +G  G  G+PG RG P   G +G PGLKG EG  G PG     +   G +G+ G  G
Sbjct: 978  SGKDGPAGLRGFPGERGLP---GAQGAPGLKGGEGPQGPPG----PVGSPGERGSAGTAG 1030

Query: 576  PEGPQGPPGHQGPPGP 591
            P G  G PG QGPPGP
Sbjct: 1031 PIGLPGRPGPQGPPGP 1046



 Score =  295 bits (754), Expect = 2e-79
 Identities = 163/357 (45%), Positives = 197/357 (55%), Gaps = 21/357 (5%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            G PG RG+ GF+G+ G PG  G  G  G  G  G +G  G+ G  G  G +G  G+ G +
Sbjct: 907  GHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKE 966

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPG---LPGCKGSPGF---DGIQGPPGPKGDPGAFGLK 370
            G KG+ G +GI G DG  G  G+PG   LPG +G+PG    +G QGPPGP G PG  G  
Sbjct: 967  GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA 1026

Query: 371  GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGN---PGPDGAPGERGGP 427
            G  G  G  G  G  G  GP+G++G PGE GP G  G  G +G    PGP G  G  G  
Sbjct: 1027 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGED 1086

Query: 428  GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487
            G++G  G PG +G +GD GE GP G  G +GPVG PG  G  G  GP+G +G  G  G E
Sbjct: 1087 GDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDE 1146

Query: 488  GARGAPGPAGP------PGDPGLMGERGEDGPAG----NGTEGFPGFPGYPGNRGAPGIN 537
            GARG PGP GP      PG PG  GE G+ GP G     G  G  G  G  G +G PG  
Sbjct: 1147 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV 1206

Query: 538  GTKGYPGLKGDEGEAGDPG--DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592
            G+ G  G KG+ GEAG+PG   +     P+G +G KG  GP G  GPPG +GPPG D
Sbjct: 1207 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDD 1263



 Score =  294 bits (752), Expect = 3e-79
 Identities = 157/351 (44%), Positives = 190/351 (54%), Gaps = 17/351 (4%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
           G PG RG PG +G RG PG PG KG+ G  G PG  G  G++G +G +G  G  G  G +
Sbjct: 535 GKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMR 594

Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD---------PGAF 367
           G  GE G RG+ G  G +G +G  G PG  G PG  G+ GPPGPKG+         PG  
Sbjct: 595 GEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQ 654

Query: 368 GLKGEKGEPGADGEAGRPGSSGPSGDEGQ---PGEPGP---PGEKGEAGDEGNPGPDGAP 421
           G  G +G PG  G  G PG  GP G  G    PG  GP   PG++G++G++G  GP G  
Sbjct: 655 GNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQ 714

Query: 422 GERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE 481
           G  G PG RG +G  G RG +G  GE G  G  G +G +G+ GD GE G IGP+G  G E
Sbjct: 715 GPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPE 774

Query: 482 GPPGSEGARGAPGPAGPPGDPGLMGERGEDG-PAGNGTEGFPGFPGYPGNRGAPGINGTK 540
           GP G  G  G PGP+G  G+ G +G  G  G P   G +G  GFPG+PG  G  G  G  
Sbjct: 775 GPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA 834

Query: 541 GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
           G PG +G  G  G P        P G  G KG  G +GP GPPG +GP GP
Sbjct: 835 GKPGPRGQRGPTG-PRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGP 884



 Score =  291 bits (744), Expect = 3e-78
 Identities = 176/376 (46%), Positives = 204/376 (54%), Gaps = 44/376 (11%)

Query: 255  ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGR---PGDLGPVGYQGMKGEKGSRGEKG 311
            A+G PGL+G  G +G  G  G PGE+G AG  G    PG  GP G  G  GEKG+ GEKG
Sbjct: 998  AQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG 1057

Query: 312  SRGPKGYKGEKGKRGI---------DGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKG 362
             +GP G  G +G  G+          G DG KGE+G PG  G KG  G +G  GPPG +G
Sbjct: 1058 PQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQG 1117

Query: 363  DPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE---------PGPPGEKGEAGDEG 413
              GA G+ G  GEPG  G+ G  G  G  G  G PG          PGPPGEKGE GD G
Sbjct: 1118 PVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVG 1177

Query: 414  NPGPDGAPGERG--GP-GERGPRGTPGT------RGPRGDPGEA---GPQGDQGREGPVG 461
              GP G PG RG  GP G  GP+G PG+       G +G+PGEA   GP G+ G  GP G
Sbjct: 1178 PMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKG 1237

Query: 462  VPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGE---RGEDGPAGN-G 517
              G+ GEAGP G  G  G +GPPG +G +G PGP G PGDPG  GE    G+DG  G+ G
Sbjct: 1238 ERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKG 1297

Query: 518  TEGFPGFPGYP---GNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYR 574
             +G PG PG P   G  G PG  G +G PG  G EG  G+ G         G +G  G  
Sbjct: 1298 EDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE----AGAEGPPGKT 1353

Query: 575  GPEGPQGPPGHQGPPG 590
            GP GPQGP G  GP G
Sbjct: 1354 GPVGPQGPAGKPGPEG 1369



 Score =  289 bits (739), Expect = 1e-77
 Identities = 162/348 (46%), Positives = 187/348 (53%), Gaps = 20/348 (5%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLG---PVGYQGMKGEKGSRGEKGSR 313
            G PG +G PG  GE+G PG  G +G AG  G  G +G   P G  G  GE G +GE G  
Sbjct: 1036 GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEP 1095

Query: 314  GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373
            G KG KG+KG+ G  G  G++G +G PG+ G  G PG  G QG  G KGD GA G  G  
Sbjct: 1096 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPP 1155

Query: 374  GEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPR 433
            G  G  G  G PG  G +GD G  G PGPPG +G  G  G  GP G PG  G  G  G +
Sbjct: 1156 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1215

Query: 434  GTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAP 493
            G PG  G  G PGEAG  G +G  G  G  G PG AGP G KG  GD+GP G+ G  G P
Sbjct: 1216 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFP 1275

Query: 494  GPAGPPGDP------GLMGERGEDGPAGN----GTEGFPGFPGYPGNRGAPGINGTKGYP 543
            G  GPPG+P      G+ G++GEDG  G     G  G  G PG PG RG PG  G +G  
Sbjct: 1276 GDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ 1335

Query: 544  GLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
            G KG +GEAG  G       P G  G  G +GP G  GP G +G PGP
Sbjct: 1336 GEKGAKGEAGAEG-------PPGKTGPVGPQGPAGKPGPEGLRGIPGP 1376



 Score =  288 bits (737), Expect = 2e-77
 Identities = 166/364 (45%), Positives = 195/364 (53%), Gaps = 31/364 (8%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP------VGYQGMKGEKGSRGE 309
            RGP G RG  G  G  GKPG  G  G  G PG PG+ GP      VG+ G KG  G  G+
Sbjct: 843  RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGK 902

Query: 310  KGSRGPKGYKGE---KGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366
             G  G  G +GE   +GK G  G  GV G  G  G  G  G  G  G  GPPG +G PGA
Sbjct: 903  DGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGA 962

Query: 367  FGLKGEKGEPGADGEAGRPGSSGPSG---DEGQPGEPGPPGEKGEAGDEGNPGPDGAPGE 423
             G +G KG+PG  G +G+ G +G  G   + G PG  G PG KG  G +G PGP G+PGE
Sbjct: 963  AGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGE 1022

Query: 424  RGG---------PGERGPRGTPGTRGPRGDPGEAGPQGDQGR---EGPVGVPGDPGEAGP 471
            RG          PG  GP+G PG  G +G PGE GPQG  GR   +GPVG+PG  G AG 
Sbjct: 1023 RGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1082

Query: 472  IGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNR 531
             G  G +G+ G PG +G++G  G  GPPG PGL G  G  G AG   +G PG  G  G  
Sbjct: 1083 PGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG--DGEPGPRGQQGMF 1140

Query: 532  GAPGINGTKGYPGLKGDEGEAGDPG-----DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQ 586
            G  G  G +G+PG  G  G  G PG      +N D+ P G  G  G RGP+GP G  G Q
Sbjct: 1141 GQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1200

Query: 587  GPPG 590
            GPPG
Sbjct: 1201 GPPG 1204



 Score =  286 bits (732), Expect = 7e-77
 Identities = 170/393 (43%), Positives = 194/393 (49%), Gaps = 63/393 (16%)

Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
           RGPPG  G  G  G  G PG  G KGE+GDPG  G  G  G  G  G+ G RG  G+ G 
Sbjct: 489 RGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGG 548

Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375
           +G  GE G +G  G DG+      PGLPG KG  G  G QGPPGP GD G  G  GE G 
Sbjct: 549 RGMPGEPGAKGDRGFDGL------PGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP 602

Query: 376 PGADGEAGRPGSSGPSGDEGQPGEP------GPPGEKGEAGDEGNPGP---DGAPGERGG 426
            G  GEAG  G  GP G  G PG+P      GPPG KG  G +G PGP    G PG +G 
Sbjct: 603 RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 662

Query: 427 PGERGPRGTPGTRGPRGDPGEA------GPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480
           PG +GP G PG +GP+G PG A      GP G  G+EG  G  G  G  GP GP GY G 
Sbjct: 663 PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGP 722

Query: 481 EGPPGSEGARGAPGPAGPPGDPGL------------------MGERGEDGPAG------- 515
            G  G++G RG  G  G  G+ G                   +G RGEDGP G       
Sbjct: 723 RGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP 782

Query: 516 ------------NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGE---AGDPG--DD 558
                        G  G PG PGYPG +G  G  G  G+PG  G++G    AG PG    
Sbjct: 783 TGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQ 842

Query: 559 NNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
                PRG +GA+G  G  GP+G  G  GPPGP
Sbjct: 843 RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGP 875



 Score =  284 bits (727), Expect = 3e-76
 Identities = 157/346 (45%), Positives = 187/346 (54%), Gaps = 21/346 (6%)

Query: 255  ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314
            A G  GL+G  G +GE G PG  G+ G  GD G  G +GP G  G +G KG  G  G  G
Sbjct: 728  ADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 787

Query: 315  PKGYKGEKGKRGIDGVDGV------KGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFG 368
            P G  GEKGK G+ G+ G       KG  G+PG PG  G  G  G+ G PGP+G  G  G
Sbjct: 788  PSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTG 847

Query: 369  LKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPG 428
             +G +G   A G  G+PG  G SG +G PG   PPGE+G  G +   GP G PG +G PG
Sbjct: 848  PRGSRG---ARGPTGKPGPKGTSGGDGPPG---PPGERGPQGPQ---GPVGFPGPKGPPG 898

Query: 429  ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEG 488
              G  G PG  G RG+ G  G  G  G  G VG  G  GE GPIG +G+ G  GPPG +G
Sbjct: 899  PPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQG 958

Query: 489  ARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGD 548
              GA G  G  GDPG  G  G+DGPA  G  GFPG  G PG +GAPG+ G +G  G  G 
Sbjct: 959  LPGAAGKEGAKGDPGPQGISGKDGPA--GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGP 1016

Query: 549  EGEAGDPGDDNNDIAPRGVKGAKGYRGPEGP---QGPPGHQGPPGP 591
             G  G+ G       P G+ G  G +GP GP   +G PG +GP GP
Sbjct: 1017 VGSPGERGSAGT-AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGP 1061



 Score =  284 bits (726), Expect = 3e-76
 Identities = 157/342 (45%), Positives = 188/342 (54%), Gaps = 13/342 (3%)

Query: 257  GPPGLRGDPGFEGERGKPGLPG------EKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310
            G PG  G  G +G+ G PGLPG       KG  G PG PG  G  G +G+ G+ G RG++
Sbjct: 784  GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 843

Query: 311  GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370
            G  GP+G +G +G  G  G  G  G  G PG PG +G  G  G  G PGPKG PG  G  
Sbjct: 844  GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 903

Query: 371  GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGER 430
            G  G PG  GE G  G +GP G  G  G  GP GE G  G+ G+PGP G PGE+G PG  
Sbjct: 904  GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 963

Query: 431  GPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGAR 490
            G  G  G  GP+G  G+ GP G +G  G  G+PG  G  G  G +G +G  GP GS G R
Sbjct: 964  GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1023

Query: 491  GAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEG 550
            G+ G AGP G PG  G +G  GPAG       G PG  G +G  G +G +G  GL G  G
Sbjct: 1024 GSAGTAGPIGLPGRPGPQGPPGPAGE-----KGAPGEKGPQGPAGRDGVQGPVGLPGPAG 1078

Query: 551  EAGDPGDDNN--DIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
             AG PG+D +  +I   G KG+KG +G  GP GPPG QGP G
Sbjct: 1079 PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG 1120



 Score =  284 bits (726), Expect = 3e-76
 Identities = 164/365 (44%), Positives = 189/365 (51%), Gaps = 41/365 (11%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGD------PGRPGDLGPVGYQGMKGEKGSRGEK 310
            G  G  G PG  G +G PG PGEKGE GD      PG PG  GP G  G  G +G  G  
Sbjct: 1147 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV 1206

Query: 311  GSRGPKGYKGEKGKRG---------IDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361
            GS G  G KGE G+ G         + G  G +GE G  G PG  G PG  G  G  GPK
Sbjct: 1207 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK 1266

Query: 362  GDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP---GPD 418
            G+PG  G  G+ G PG  G AG+ G  G  G++G PG+PGPPG  GEAG  G P   GP 
Sbjct: 1267 GNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPP 1326

Query: 419  GAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYR 478
            GA G  G  GE+G +G  G  GP G  G  GPQG  G+ GP G+ G PG           
Sbjct: 1327 GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV--------- 1377

Query: 479  GDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGIN 537
            G++G PG+ G  G PGP GPPG PGL G+ G  G  G+ G  G  G PG  G +G  G+ 
Sbjct: 1378 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1437

Query: 538  GTKGYPGLKGD------EGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQ------GPPGH 585
            GT+G PG KGD       G  G PG       P+G KG KG  GP G +      GPPG 
Sbjct: 1438 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLP-GPQGPKGNKGSTGPAGQKGDSGLPGPPGS 1496

Query: 586  QGPPG 590
             GPPG
Sbjct: 1497 PGPPG 1501



 Score =  282 bits (722), Expect = 1e-75
 Identities = 168/378 (44%), Positives = 193/378 (51%), Gaps = 44/378 (11%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            G  G  G PG  GE+G PG  G++G  GDPG  G  G  G  G++G  G RG  G++G  
Sbjct: 943  GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1002

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376
            G KG +G +G  G  G  GE G  G  G  G PG  G QGPPGP G+ GA G KG +G  
Sbjct: 1003 GLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPA 1062

Query: 377  GAD---------GEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPD------GAP 421
            G D         G AG  GS G  GD+G+ GEPG  G KG+ G+ G PGP       GAP
Sbjct: 1063 GRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAP 1122

Query: 422  GERGGPGERGPRGTPGTRGPRGD------------------PGEAGPQGDQGREGPVGVP 463
            G  GG GE GPRG  G  G +GD                  PG  G +G+ G  GP+G P
Sbjct: 1123 GIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1182

Query: 464  GDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGD---PGLMGERGEDGPAG----N 516
            G PG  GP GP G  G +GPPGS G+ G  G  G PG+   PG  GE G  GP G     
Sbjct: 1183 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1242

Query: 517  GTEGFPGFPGYPGNRGAPGINGTKGYP---GLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573
            G  G PG  G PG +G PG +G KG P   G  GD G  G+PG    D    G KG  G 
Sbjct: 1243 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQD-GVGGDKGEDGD 1301

Query: 574  RGPEGPQGPPGHQGPPGP 591
             G  GP GP G  GPPGP
Sbjct: 1302 PGQPGPPGPSGEAGPPGP 1319



 Score =  281 bits (720), Expect = 2e-75
 Identities = 165/374 (44%), Positives = 196/374 (52%), Gaps = 41/374 (10%)

Query: 257  GPPGLRGDPG---FEGERGKPGLPGEKGEAGDPGR---PGDLGPVGYQGMKGEKGSRGEK 310
            GPPG +G+PG     G +G  G PGEKG  G PG    PG  GP G+ G +G+ G +G  
Sbjct: 649  GPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL 708

Query: 311  GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370
            G  GP+G  G  G RG+ G DGV+G  G  G  G  G PGF G  G  G +G+ G  G +
Sbjct: 709  GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 768

Query: 371  GEKGEPGADGEAGRPGSSGPSGDEGQ------PGEPGPPGEKGEAGDEGNPGPDGAPGER 424
            GE G  G  G AG  G  GPSG  G+      PG PG PG +G  G  G PG  GA GE+
Sbjct: 769  GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 828

Query: 425  G--------GP-GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475
            G        GP G+RGP G  G+RG RG  G+ GP+G  G +GP G PG+ G  GP GP 
Sbjct: 829  GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPV 888

Query: 476  GYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-------------NGTEGFP 522
            G+ G +GPPG  G  G PG  G  G+ G  G+ G  GP G              G  G P
Sbjct: 889  GFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHP 948

Query: 523  GFPGYPGNRGAPGI---NGTKGYP---GLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGP 576
            G PG PG +G PG     G KG P   G+ G +G AG  G       P G +GA G +G 
Sbjct: 949  GPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLP-GAQGAPGLKGG 1007

Query: 577  EGPQGPPGHQGPPG 590
            EGPQGPPG  G PG
Sbjct: 1008 EGPQGPPGPVGSPG 1021



 Score =  278 bits (710), Expect = 2e-74
 Identities = 159/350 (45%), Positives = 190/350 (54%), Gaps = 23/350 (6%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
           G PGL GD G  GERG  G PG  G+ G  G  G++GP   +G+ GE G RG  G RG  
Sbjct: 565 GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP---RGLPGEAGPRGLLGPRGTP 621

Query: 317 GYKGEKGKRGIDGVDGVKGEMG---YPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373
           G  G+ G  G+DG  G KG MG    PG PG +G+PG  G+ GP GP G PG  G +G+ 
Sbjct: 622 GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP 681

Query: 374 GE---PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGER 430
           G    PGADG  G PG  G SG++G  G PGP G  G  G  G  G DG  G +G  GE+
Sbjct: 682 GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK 741

Query: 431 GPRGTPG------TRGPRGDPGEAGPQGDQGREGP---VGVPGDPGEAGPIGPKGYRGDE 481
           G  G PG       +G RG+ G+ GP+G+ G EGP    G  GDPG +G  G KG  G  
Sbjct: 742 GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP 801

Query: 482 GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTK 540
           G PG  G +G  G  G PG PG  GE+G  G AG  G  G  G  G  G+RGA G  G  
Sbjct: 802 GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKP 861

Query: 541 GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           G  G  G +G  G PG+      P+G +G  G+ GP+GP GPPG  G PG
Sbjct: 862 GPKGTSGGDGPPGPPGER----GPQGPQGPVGFPGPKGPPGPPGKDGLPG 907



 Score =  277 bits (709), Expect = 3e-74
 Identities = 157/344 (45%), Positives = 182/344 (52%), Gaps = 21/344 (6%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            RGP G +G  GF G +G PG PG+ G    PG PG  G  G+QG  G  G  G  G +GP
Sbjct: 879  RGPQGPQGPVGFPGPKGPPGPPGKDGL---PGHPGQRGETGFQGKTGPPGPGGVVGPQGP 935

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375
             G  G  G+RG  G  G  GE G PG  G +G+ G  G QG  G  G  G  G  GE+G 
Sbjct: 936  TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL 995

Query: 376  PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD---EGNPGPDGAPG---ERGGPGE 429
            PGA G  G  G  GP G  G  G PG  G  G AG     G PGP G PG   E+G PGE
Sbjct: 996  PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1055

Query: 430  RGPRGTPG---TRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGS 486
            +GP+G  G    +GP G PG AGP G  G +G  G  G+PG+ G  G KG  G  GPPG 
Sbjct: 1056 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1115

Query: 487  EGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLK 546
            +G  GAPG AG  G+PG  G++G  G  G+  EG  GFPG PG  G  G+ G  G  G  
Sbjct: 1116 QGPVGAPGIAGGDGEPGPRGQQGMFGQKGD--EGARGFPGPPGPIGLQGLPGPPGEKGEN 1173

Query: 547  GDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
            GD G  G PG       P G +G +G  G +GPQGPPG  G  G
Sbjct: 1174 GDVGPMGPPG-------PPGPRGPQGPNGADGPQGPPGSVGSVG 1210



 Score =  276 bits (705), Expect = 9e-74
 Identities = 161/369 (43%), Positives = 187/369 (50%), Gaps = 36/369 (9%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            RG PG +G PG +G  G  G PG  G  G+ G  G  GP+G   + G  G +G  G  G 
Sbjct: 993  RGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIG---LPGRPGPQGPPGPAGE 1049

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGP---PGPKGDPGAFGLKGE 372
            KG  GEKG +G  G DGV+G +G PG  G  GSPG DG +G    PG KG  G  G  G 
Sbjct: 1050 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP 1109

Query: 373  KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGP 432
             G PG  G  G PG +G  G+ G  G+ G  G+KG+ G  G PGP G  G +G PG  G 
Sbjct: 1110 PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1169

Query: 433  RGTPGTRGPRGDPGEAGPQGDQ---GREGPVGVP------------GDPGEAGPIGPKGY 477
            +G  G  GP G PG  GP+G Q   G +GP G P            G+PGEAG  GP G 
Sbjct: 1170 KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1229

Query: 478  RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGI 536
             G  GP G  G +G  GP G  G PG  G  G+DGP GN G  GFPG PG PG  G  G 
Sbjct: 1230 AGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQ 1289

Query: 537  NGT---------KGYPGLKGDEGEAGDPGDDNNDIAP-----RGVKGAKGYRGPEGPQGP 582
            +G           G PG  G  GEAG PG       P      G +G KG +G  G +GP
Sbjct: 1290 DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP 1349

Query: 583  PGHQGPPGP 591
            PG  GP GP
Sbjct: 1350 PGKTGPVGP 1358



 Score =  275 bits (704), Expect = 1e-73
 Identities = 156/351 (44%), Positives = 182/351 (51%), Gaps = 30/351 (8%)

Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
           RG PG  G PG  G  G PG  G  G  G+PG PG  G  G QG+ G +G  G  G +GP
Sbjct: 618 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 677

Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGL------ 369
           +G  G  G  G DG  G  G+ G  G  G  G PG  G  G PGP+G  GA G+      
Sbjct: 678 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 737

Query: 370 KGEKGE---PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGG 426
           KGEKGE   PG  G+ G  G  G  G  G  GE GP G KG AG  G+PGP G  GE+G 
Sbjct: 738 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 797

Query: 427 PGERGPRGTPGTRGPRGD---PGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGP 483
            G  G  G PG +GP+G    PG  G  G++G  G  G PG  G+ GP GP+G RG  GP
Sbjct: 798 LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 857

Query: 484 PGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYP 543
            G  G +G  G  GPPG PG  G +G  GP         GFPG  G  G PG +G  G+P
Sbjct: 858 TGKPGPKGTSGGDGPPGPPGERGPQGPQGPV--------GFPGPKGPPGPPGKDGLPGHP 909

Query: 544 GLKGD---EGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
           G +G+   +G+ G PG       P GV G +G  G  GP G  GH GPPGP
Sbjct: 910 GQRGETGFQGKTGPPG-------PGGVVGPQGPTGETGPIGERGHPGPPGP 953



 Score =  266 bits (681), Expect = 6e-71
 Identities = 165/398 (41%), Positives = 193/398 (48%), Gaps = 59/398 (14%)

Query: 253 QPARGPPGL--RGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310
           +PA   PG+   G PG  G  G  G PG +G  G PG PGD GP G  G+ G  G  G  
Sbjct: 391 EPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPP 450

Query: 311 GSR-------GPKGYKGE--------------------KGKRGIDGVDGVKGEMGYPGLP 343
           G+        G  G KG                     +G  G  G+ G  G +G PG  
Sbjct: 451 GTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSS 510

Query: 344 GCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPP 403
           G KG  G  G QGP G +G PG  G  G++G PGADG  G PG  G  GD G  G PG P
Sbjct: 511 GAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLP 570

Query: 404 GEKGEAGDEGNPGPDGAPGE---RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPV 460
           G+KG  G+ G  GP G PG+   RG  GE GPRG PG  GPRG  G  G  G  G+ G  
Sbjct: 571 GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 630

Query: 461 GVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTE 519
           GV G PG  G +GP+G  G  G  G+ G +G PGP GP G PG  G +G+ G AG  G +
Sbjct: 631 GVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 690

Query: 520 GFPGFP---------------------GYPGNRGAPGINGTKGYPGLKGDEGEAGDPG-- 556
           G PG P                     GYPG RG  G +G +G  G KG++GE G PG  
Sbjct: 691 GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 750

Query: 557 DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGP---PGP 591
            D      RG  G  G RG +GP+GP G  GP   PGP
Sbjct: 751 GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 788



 Score =  246 bits (629), Expect = 6e-65
 Identities = 139/295 (47%), Positives = 167/295 (56%), Gaps = 14/295 (4%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGE---KGSRGEKGS 312
            +G PG  G+PG  GE G  G  GE+GE G+ G PG  GP G +G  G+   KG+ G  G 
Sbjct: 1215 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1274

Query: 313  RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372
             G  G  GE G  G DGV G KGE G PG PG  G  G  G  GPPG +G PGA G +G 
Sbjct: 1275 PGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGR 1334

Query: 373  KGEPGADGEAGR---PGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGE 429
            +GE GA GEAG    PG +GP G +G  G+PGP G +G  G  G  G  GA G+ G PG 
Sbjct: 1335 QGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGP 1394

Query: 430  RGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGA 489
             GP G PG +G   DPG    +G++G  G +G+ G PGE G  G +G  G +G PG++G 
Sbjct: 1395 MGPPGLPGLKG---DPGS---KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGD 1448

Query: 490  RGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPG 544
             G PGPAGP G PG  G  G  GP GN  +G  G  G  G+ G PG  G+ G PG
Sbjct: 1449 GGIPGPAGPLGPPGPPGLPGPQGPKGN--KGSTGPAGQKGDSGLPGPPGSPGPPG 1501



 Score =  225 bits (573), Expect = 2e-58
 Identities = 118/255 (46%), Positives = 138/255 (54%), Gaps = 9/255 (3%)

Query: 255  ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGE----- 309
            A GPPG +G PG +G +G PG  G  G+ G PG PG  G  G  G KGE G  G+     
Sbjct: 1250 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1309

Query: 310  -KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFG 368
              G  GP G  G++G  G  G +G +GE G  G  G +G PG  G  GP GP G PG  G
Sbjct: 1310 PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEG 1369

Query: 369  LKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPG 428
            L+G  G  G  G  G  G  GP G  G PG PG  G+ G  G++G+PG  G  G  G  G
Sbjct: 1370 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG 1429

Query: 429  ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEG 488
            E+G RG PGT   +G PG  G  G  G  GP+G PG PG  GP GPKG +G  GP G +G
Sbjct: 1430 EKGDRGLPGT---QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG 1486

Query: 489  ARGAPGPAGPPGDPG 503
              G PGP G PG PG
Sbjct: 1487 DSGLPGPPGSPGPPG 1501



 Score =  213 bits (541), Expect = 1e-54
 Identities = 151/380 (39%), Positives = 175/380 (46%), Gaps = 70/380 (18%)

Query: 273 KPGLPGEKGEAGDPGRPGDLG----PVGYQGMKGEKGSRGE----------KGSRGPKGY 318
           KP  P    E   PG P +       +   G  GEKG +GE          +G  GP G 
Sbjct: 353 KPTSP--PNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGP 410

Query: 319 KGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD-PGAFGLKGEKGEPG 377
            G  G  G+ G  G  G+ G  G PG  G PG DG+ GPPG     P  +G  G KG   
Sbjct: 411 AGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTI 470

Query: 378 ADGEA--------------GRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGE 423
           +  EA              G PG  G +G  G  G PG  G KGE+GD G  GP G  G 
Sbjct: 471 SAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGP 530

Query: 424 RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGP 483
            G  G+ G RG PG  G RG PGE G +GD+G +G  G+PGD G       +G RG +GP
Sbjct: 531 PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGH------RGERGPQGP 584

Query: 484 PGSE------------GARGAPGPAGP------------PGDPGLMGERGEDGPAGN-GT 518
           PG              G RG PG AGP            PG PG+ G  G  GP GN G 
Sbjct: 585 PGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGP 644

Query: 519 EGFPGFPGY---PGNRGAPGINGTKGYPGLKGDEGE---AGDPGDDNNDIAP--RGVKGA 570
           +G PG PG    PG +G PG  G  G PG KG +G+   AG PG D     P   G  G 
Sbjct: 645 QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGE 704

Query: 571 KGYRGPEGPQGPPGHQGPPG 590
           KG  GP GPQGP G+ GP G
Sbjct: 705 KGALGPPGPQGPIGYPGPRG 724



 Score =  194 bits (493), Expect = 4e-49
 Identities = 107/224 (47%), Positives = 126/224 (56%), Gaps = 21/224 (9%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP---VGYQGMKGEKGSRGEKGSR 313
            G  G+ GD G +G+ G+PG PG  GEAG PG PG  GP    G +G +GEKG++GE G+ 
Sbjct: 1288 GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAE 1347

Query: 314  GPKGY------KGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAF 367
            GP G       +G  GK G +G+ G+ G +G  GLPG  G    DG  GP GP G PG  
Sbjct: 1348 GPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ---DGPPGPMGPPGLPGLK 1404

Query: 368  ---GLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGER 424
               G KGEKG PG  G  G PG  G  GD G PG  G PG KG+ G  G  GP G PG  
Sbjct: 1405 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP 1464

Query: 425  GGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGE 468
            G PG +GP+G  G+ GP      AG +GD G  GP G PG PGE
Sbjct: 1465 GLPGPQGPKGNKGSTGP------AGQKGDSGLPGPPGSPGPPGE 1502



 Score =  157 bits (398), Expect = 4e-38
 Identities = 99/238 (41%), Positives = 114/238 (47%), Gaps = 31/238 (13%)

Query: 365 GAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE--PGPPGEKGEAGDEGNPGPDGAPG 422
           GA+G KG+KGEP                   +PG    GPPG  G AG  G PG  G  G
Sbjct: 381 GAYGEKGQKGEPAVV----------------EPGMLVEGPPGPAGPAGIMGPPGLQGPTG 424

Query: 423 ERGGPGERGPRGTPGTRGPRGDPGEAGPQ-------GDQGREGPVGVPGDPGEAGPIGPK 475
             G PG+RGP G PG  G  G PG  G         G  G +GP  +     +A  I  +
Sbjct: 425 PPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPT-ISAQEAQAQAILQQ 483

Query: 476 GYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAP 534
                 GPPG  G  G PGP G PG  G  GE G+ GP G  G +G PG  G PG RG P
Sbjct: 484 ARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRP 543

Query: 535 GINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592
           G +G +G PG   + G  GD G D     P G KG +G RGP+GP GPPG  G  G D
Sbjct: 544 GADGGRGMPG---EPGAKGDRGFDGLPGLP-GDKGHRGERGPQGPPGPPGDDGMRGED 597



 Score =  103 bits (258), Expect = 6e-22
 Identities = 61/141 (43%), Positives = 73/141 (51%), Gaps = 24/141 (17%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            GPPG  G PG  G +G PG    KGE G PG  G +GP G QG KG++G  G +GS    
Sbjct: 1390 GPPGPMGPPGLPGLKGDPG---SKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGS---- 1442

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376
                           G KG+ G PG  G  G PG  G+ GP GPKG+ G+ G  G+KG+ 
Sbjct: 1443 --------------PGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDS 1488

Query: 377  GADGEAGRPGSSGPSGDEGQP 397
            G  G    PGS GP G+  QP
Sbjct: 1489 GLPGP---PGSPGPPGEVIQP 1506


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  303 bits (775), Expect = 7e-82
 Identities = 166/357 (46%), Positives = 196/357 (54%), Gaps = 29/357 (8%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            G PG+ G  G  G RG+ G+ G+KG+ G  G PG  GP+G QG+ G  G +GE G  GP 
Sbjct: 1159 GAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPM 1218

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGC------KGSPGFDGIQGPPGPKGDPGAFGLK 370
            G  G  G RG  G +G  G  G PG  G       KG PG  G  GPPG  G  G  G +
Sbjct: 1219 GPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGER 1278

Query: 371  GEKGEPGADGEAGRPGSSGPSGDEGQ---------PGEPGPPGEKGEAGDEG---NPGPD 418
            GEKGE G  G AG PG+ GP GD+G          PG+PGPPGE G AG +G   + G D
Sbjct: 1279 GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGED 1338

Query: 419  GAPGERGGPG---ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475
            G PG+ G PG   E GP G PG RGP G  G  G QG++G +G  G  G PG+ GP+GP+
Sbjct: 1339 GDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQ 1398

Query: 476  GYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAP 534
            G     G PG EG RG PGP G  G PG  G+ G  GP G  G  G  G PG  G +G P
Sbjct: 1399 G---PAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHP 1455

Query: 535  GINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
            G+ G  G PG +G++G+ G PG   +     G KG  G  GP GP GPPG  G PGP
Sbjct: 1456 GLIGLIGPPGEQGEKGDRGLPGTQGSP----GAKGDGGIPGPAGPLGPPGPPGLPGP 1508



 Score =  296 bits (758), Expect = 7e-80
 Identities = 170/376 (45%), Positives = 199/376 (52%), Gaps = 47/376 (12%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            +G PGL G PG +G  G PG  G+ GE G  G PG  GP+GY G +G KG+ G +G +G 
Sbjct: 717  QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 776

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375
            KG KGE G  G  G  G+KG+ G  G  G +G  G +G +G  GP GDPG  G  GEKG+
Sbjct: 777  KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 836

Query: 376  PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP---------GPDGAPGERGG 426
             G  G  G PG  GP G  G PG PG  GEKG  G  G P         GP G+ G RG 
Sbjct: 837  LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 896

Query: 427  PGERGPRGTPGTRGPRGDPGEAGPQGDQGR---EGPVGVPGDP----------------- 466
             G+ GP+GT G  GP G PGE GPQG QG     GP G PG P                 
Sbjct: 897  TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGF 956

Query: 467  -GEAGPIGPKGYRGDEGPPGSE---GARGAPGPAGPPGDPGLMGERGEDGPAG------- 515
             G+ GP GP G  G +GP G     G RG PGP GPPG+ GL G  G++G  G       
Sbjct: 957  QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGI 1016

Query: 516  NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRG 575
            +G +G  G  G+PG RG P   G +G PGLKG EG  G PG     +   G +G+ G  G
Sbjct: 1017 SGKDGPAGLRGFPGERGLP---GAQGAPGLKGGEGPQGPPG----PVGSPGERGSAGTAG 1069

Query: 576  PEGPQGPPGHQGPPGP 591
            P G  G PG QGPPGP
Sbjct: 1070 PIGLPGRPGPQGPPGP 1085



 Score =  295 bits (754), Expect = 2e-79
 Identities = 163/357 (45%), Positives = 197/357 (55%), Gaps = 21/357 (5%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            G PG RG+ GF+G+ G PG  G  G  G  G  G +G  G+ G  G  G +G  G+ G +
Sbjct: 946  GHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKE 1005

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPG---LPGCKGSPGF---DGIQGPPGPKGDPGAFGLK 370
            G KG+ G +GI G DG  G  G+PG   LPG +G+PG    +G QGPPGP G PG  G  
Sbjct: 1006 GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA 1065

Query: 371  GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGN---PGPDGAPGERGGP 427
            G  G  G  G  G  G  GP+G++G PGE GP G  G  G +G    PGP G  G  G  
Sbjct: 1066 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGED 1125

Query: 428  GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487
            G++G  G PG +G +GD GE GP G  G +GPVG PG  G  G  GP+G +G  G  G E
Sbjct: 1126 GDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDE 1185

Query: 488  GARGAPGPAGP------PGDPGLMGERGEDGPAG----NGTEGFPGFPGYPGNRGAPGIN 537
            GARG PGP GP      PG PG  GE G+ GP G     G  G  G  G  G +G PG  
Sbjct: 1186 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV 1245

Query: 538  GTKGYPGLKGDEGEAGDPG--DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592
            G+ G  G KG+ GEAG+PG   +     P+G +G KG  GP G  GPPG +GPPG D
Sbjct: 1246 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDD 1302



 Score =  294 bits (752), Expect = 3e-79
 Identities = 157/351 (44%), Positives = 190/351 (54%), Gaps = 17/351 (4%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
           G PG RG PG +G RG PG PG KG+ G  G PG  G  G++G +G +G  G  G  G +
Sbjct: 574 GKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMR 633

Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD---------PGAF 367
           G  GE G RG+ G  G +G +G  G PG  G PG  G+ GPPGPKG+         PG  
Sbjct: 634 GEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQ 693

Query: 368 GLKGEKGEPGADGEAGRPGSSGPSGDEGQ---PGEPGP---PGEKGEAGDEGNPGPDGAP 421
           G  G +G PG  G  G PG  GP G  G    PG  GP   PG++G++G++G  GP G  
Sbjct: 694 GNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQ 753

Query: 422 GERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE 481
           G  G PG RG +G  G RG +G  GE G  G  G +G +G+ GD GE G IGP+G  G E
Sbjct: 754 GPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPE 813

Query: 482 GPPGSEGARGAPGPAGPPGDPGLMGERGEDG-PAGNGTEGFPGFPGYPGNRGAPGINGTK 540
           GP G  G  G PGP+G  G+ G +G  G  G P   G +G  GFPG+PG  G  G  G  
Sbjct: 814 GPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA 873

Query: 541 GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
           G PG +G  G  G P        P G  G KG  G +GP GPPG +GP GP
Sbjct: 874 GKPGPRGQRGPTG-PRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGP 923



 Score =  291 bits (744), Expect = 3e-78
 Identities = 176/376 (46%), Positives = 204/376 (54%), Gaps = 44/376 (11%)

Query: 255  ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGR---PGDLGPVGYQGMKGEKGSRGEKG 311
            A+G PGL+G  G +G  G  G PGE+G AG  G    PG  GP G  G  GEKG+ GEKG
Sbjct: 1037 AQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG 1096

Query: 312  SRGPKGYKGEKGKRGI---------DGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKG 362
             +GP G  G +G  G+          G DG KGE+G PG  G KG  G +G  GPPG +G
Sbjct: 1097 PQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQG 1156

Query: 363  DPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE---------PGPPGEKGEAGDEG 413
              GA G+ G  GEPG  G+ G  G  G  G  G PG          PGPPGEKGE GD G
Sbjct: 1157 PVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVG 1216

Query: 414  NPGPDGAPGERG--GP-GERGPRGTPGT------RGPRGDPGEA---GPQGDQGREGPVG 461
              GP G PG RG  GP G  GP+G PG+       G +G+PGEA   GP G+ G  GP G
Sbjct: 1217 PMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKG 1276

Query: 462  VPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGE---RGEDGPAGN-G 517
              G+ GEAGP G  G  G +GPPG +G +G PGP G PGDPG  GE    G+DG  G+ G
Sbjct: 1277 ERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKG 1336

Query: 518  TEGFPGFPGYP---GNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYR 574
             +G PG PG P   G  G PG  G +G PG  G EG  G+ G         G +G  G  
Sbjct: 1337 EDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE----AGAEGPPGKT 1392

Query: 575  GPEGPQGPPGHQGPPG 590
            GP GPQGP G  GP G
Sbjct: 1393 GPVGPQGPAGKPGPEG 1408



 Score =  289 bits (739), Expect = 1e-77
 Identities = 162/348 (46%), Positives = 187/348 (53%), Gaps = 20/348 (5%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLG---PVGYQGMKGEKGSRGEKGSR 313
            G PG +G PG  GE+G PG  G +G AG  G  G +G   P G  G  GE G +GE G  
Sbjct: 1075 GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEP 1134

Query: 314  GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373
            G KG KG+KG+ G  G  G++G +G PG+ G  G PG  G QG  G KGD GA G  G  
Sbjct: 1135 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPP 1194

Query: 374  GEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPR 433
            G  G  G  G PG  G +GD G  G PGPPG +G  G  G  GP G PG  G  G  G +
Sbjct: 1195 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1254

Query: 434  GTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAP 493
            G PG  G  G PGEAG  G +G  G  G  G PG AGP G KG  GD+GP G+ G  G P
Sbjct: 1255 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFP 1314

Query: 494  GPAGPPGDP------GLMGERGEDGPAGN----GTEGFPGFPGYPGNRGAPGINGTKGYP 543
            G  GPPG+P      G+ G++GEDG  G     G  G  G PG PG RG PG  G +G  
Sbjct: 1315 GDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ 1374

Query: 544  GLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
            G KG +GEAG  G       P G  G  G +GP G  GP G +G PGP
Sbjct: 1375 GEKGAKGEAGAEG-------PPGKTGPVGPQGPAGKPGPEGLRGIPGP 1415



 Score =  288 bits (737), Expect = 2e-77
 Identities = 166/364 (45%), Positives = 195/364 (53%), Gaps = 31/364 (8%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP------VGYQGMKGEKGSRGE 309
            RGP G RG  G  G  GKPG  G  G  G PG PG+ GP      VG+ G KG  G  G+
Sbjct: 882  RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGK 941

Query: 310  KGSRGPKGYKGE---KGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366
             G  G  G +GE   +GK G  G  GV G  G  G  G  G  G  G  GPPG +G PGA
Sbjct: 942  DGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGA 1001

Query: 367  FGLKGEKGEPGADGEAGRPGSSGPSG---DEGQPGEPGPPGEKGEAGDEGNPGPDGAPGE 423
             G +G KG+PG  G +G+ G +G  G   + G PG  G PG KG  G +G PGP G+PGE
Sbjct: 1002 AGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGE 1061

Query: 424  RGG---------PGERGPRGTPGTRGPRGDPGEAGPQGDQGR---EGPVGVPGDPGEAGP 471
            RG          PG  GP+G PG  G +G PGE GPQG  GR   +GPVG+PG  G AG 
Sbjct: 1062 RGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1121

Query: 472  IGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNR 531
             G  G +G+ G PG +G++G  G  GPPG PGL G  G  G AG   +G PG  G  G  
Sbjct: 1122 PGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG--DGEPGPRGQQGMF 1179

Query: 532  GAPGINGTKGYPGLKGDEGEAGDPG-----DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQ 586
            G  G  G +G+PG  G  G  G PG      +N D+ P G  G  G RGP+GP G  G Q
Sbjct: 1180 GQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1239

Query: 587  GPPG 590
            GPPG
Sbjct: 1240 GPPG 1243



 Score =  286 bits (732), Expect = 7e-77
 Identities = 170/393 (43%), Positives = 194/393 (49%), Gaps = 63/393 (16%)

Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
           RGPPG  G  G  G  G PG  G KGE+GDPG  G  G  G  G  G+ G RG  G+ G 
Sbjct: 528 RGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGG 587

Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375
           +G  GE G +G  G DG+      PGLPG KG  G  G QGPPGP GD G  G  GE G 
Sbjct: 588 RGMPGEPGAKGDRGFDGL------PGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP 641

Query: 376 PGADGEAGRPGSSGPSGDEGQPGEP------GPPGEKGEAGDEGNPGP---DGAPGERGG 426
            G  GEAG  G  GP G  G PG+P      GPPG KG  G +G PGP    G PG +G 
Sbjct: 642 RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 701

Query: 427 PGERGPRGTPGTRGPRGDPGEA------GPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480
           PG +GP G PG +GP+G PG A      GP G  G+EG  G  G  G  GP GP GY G 
Sbjct: 702 PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGP 761

Query: 481 EGPPGSEGARGAPGPAGPPGDPGL------------------MGERGEDGPAG------- 515
            G  G++G RG  G  G  G+ G                   +G RGEDGP G       
Sbjct: 762 RGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP 821

Query: 516 ------------NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGE---AGDPG--DD 558
                        G  G PG PGYPG +G  G  G  G+PG  G++G    AG PG    
Sbjct: 822 TGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQ 881

Query: 559 NNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
                PRG +GA+G  G  GP+G  G  GPPGP
Sbjct: 882 RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGP 914



 Score =  284 bits (727), Expect = 3e-76
 Identities = 157/346 (45%), Positives = 187/346 (54%), Gaps = 21/346 (6%)

Query: 255  ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314
            A G  GL+G  G +GE G PG  G+ G  GD G  G +GP G  G +G KG  G  G  G
Sbjct: 767  ADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 826

Query: 315  PKGYKGEKGKRGIDGVDGV------KGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFG 368
            P G  GEKGK G+ G+ G       KG  G+PG PG  G  G  G+ G PGP+G  G  G
Sbjct: 827  PSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTG 886

Query: 369  LKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPG 428
             +G +G   A G  G+PG  G SG +G PG   PPGE+G  G +   GP G PG +G PG
Sbjct: 887  PRGSRG---ARGPTGKPGPKGTSGGDGPPG---PPGERGPQGPQ---GPVGFPGPKGPPG 937

Query: 429  ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEG 488
              G  G PG  G RG+ G  G  G  G  G VG  G  GE GPIG +G+ G  GPPG +G
Sbjct: 938  PPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQG 997

Query: 489  ARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGD 548
              GA G  G  GDPG  G  G+DGPA  G  GFPG  G PG +GAPG+ G +G  G  G 
Sbjct: 998  LPGAAGKEGAKGDPGPQGISGKDGPA--GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGP 1055

Query: 549  EGEAGDPGDDNNDIAPRGVKGAKGYRGPEGP---QGPPGHQGPPGP 591
             G  G+ G       P G+ G  G +GP GP   +G PG +GP GP
Sbjct: 1056 VGSPGERGSAGT-AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGP 1100



 Score =  284 bits (726), Expect = 3e-76
 Identities = 157/342 (45%), Positives = 188/342 (54%), Gaps = 13/342 (3%)

Query: 257  GPPGLRGDPGFEGERGKPGLPG------EKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310
            G PG  G  G +G+ G PGLPG       KG  G PG PG  G  G +G+ G+ G RG++
Sbjct: 823  GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 882

Query: 311  GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370
            G  GP+G +G +G  G  G  G  G  G PG PG +G  G  G  G PGPKG PG  G  
Sbjct: 883  GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 942

Query: 371  GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGER 430
            G  G PG  GE G  G +GP G  G  G  GP GE G  G+ G+PGP G PGE+G PG  
Sbjct: 943  GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 1002

Query: 431  GPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGAR 490
            G  G  G  GP+G  G+ GP G +G  G  G+PG  G  G  G +G +G  GP GS G R
Sbjct: 1003 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1062

Query: 491  GAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEG 550
            G+ G AGP G PG  G +G  GPAG       G PG  G +G  G +G +G  GL G  G
Sbjct: 1063 GSAGTAGPIGLPGRPGPQGPPGPAGE-----KGAPGEKGPQGPAGRDGVQGPVGLPGPAG 1117

Query: 551  EAGDPGDDNN--DIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
             AG PG+D +  +I   G KG+KG +G  GP GPPG QGP G
Sbjct: 1118 PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG 1159



 Score =  284 bits (726), Expect = 3e-76
 Identities = 164/365 (44%), Positives = 189/365 (51%), Gaps = 41/365 (11%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGD------PGRPGDLGPVGYQGMKGEKGSRGEK 310
            G  G  G PG  G +G PG PGEKGE GD      PG PG  GP G  G  G +G  G  
Sbjct: 1186 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV 1245

Query: 311  GSRGPKGYKGEKGKRG---------IDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361
            GS G  G KGE G+ G         + G  G +GE G  G PG  G PG  G  G  GPK
Sbjct: 1246 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK 1305

Query: 362  GDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP---GPD 418
            G+PG  G  G+ G PG  G AG+ G  G  G++G PG+PGPPG  GEAG  G P   GP 
Sbjct: 1306 GNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPP 1365

Query: 419  GAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYR 478
            GA G  G  GE+G +G  G  GP G  G  GPQG  G+ GP G+ G PG           
Sbjct: 1366 GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV--------- 1416

Query: 479  GDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGIN 537
            G++G PG+ G  G PGP GPPG PGL G+ G  G  G+ G  G  G PG  G +G  G+ 
Sbjct: 1417 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1476

Query: 538  GTKGYPGLKGD------EGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQ------GPPGH 585
            GT+G PG KGD       G  G PG       P+G KG KG  GP G +      GPPG 
Sbjct: 1477 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLP-GPQGPKGNKGSTGPAGQKGDSGLPGPPGS 1535

Query: 586  QGPPG 590
             GPPG
Sbjct: 1536 PGPPG 1540



 Score =  282 bits (722), Expect = 1e-75
 Identities = 168/378 (44%), Positives = 193/378 (51%), Gaps = 44/378 (11%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            G  G  G PG  GE+G PG  G++G  GDPG  G  G  G  G++G  G RG  G++G  
Sbjct: 982  GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1041

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376
            G KG +G +G  G  G  GE G  G  G  G PG  G QGPPGP G+ GA G KG +G  
Sbjct: 1042 GLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPA 1101

Query: 377  GAD---------GEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPD------GAP 421
            G D         G AG  GS G  GD+G+ GEPG  G KG+ G+ G PGP       GAP
Sbjct: 1102 GRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAP 1161

Query: 422  GERGGPGERGPRGTPGTRGPRGD------------------PGEAGPQGDQGREGPVGVP 463
            G  GG GE GPRG  G  G +GD                  PG  G +G+ G  GP+G P
Sbjct: 1162 GIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1221

Query: 464  GDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGD---PGLMGERGEDGPAG----N 516
            G PG  GP GP G  G +GPPGS G+ G  G  G PG+   PG  GE G  GP G     
Sbjct: 1222 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1281

Query: 517  GTEGFPGFPGYPGNRGAPGINGTKGYP---GLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573
            G  G PG  G PG +G PG +G KG P   G  GD G  G+PG    D    G KG  G 
Sbjct: 1282 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQD-GVGGDKGEDGD 1340

Query: 574  RGPEGPQGPPGHQGPPGP 591
             G  GP GP G  GPPGP
Sbjct: 1341 PGQPGPPGPSGEAGPPGP 1358



 Score =  281 bits (720), Expect = 2e-75
 Identities = 165/374 (44%), Positives = 196/374 (52%), Gaps = 41/374 (10%)

Query: 257  GPPGLRGDPG---FEGERGKPGLPGEKGEAGDPGR---PGDLGPVGYQGMKGEKGSRGEK 310
            GPPG +G+PG     G +G  G PGEKG  G PG    PG  GP G+ G +G+ G +G  
Sbjct: 688  GPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL 747

Query: 311  GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370
            G  GP+G  G  G RG+ G DGV+G  G  G  G  G PGF G  G  G +G+ G  G +
Sbjct: 748  GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 807

Query: 371  GEKGEPGADGEAGRPGSSGPSGDEGQ------PGEPGPPGEKGEAGDEGNPGPDGAPGER 424
            GE G  G  G AG  G  GPSG  G+      PG PG PG +G  G  G PG  GA GE+
Sbjct: 808  GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 867

Query: 425  G--------GP-GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475
            G        GP G+RGP G  G+RG RG  G+ GP+G  G +GP G PG+ G  GP GP 
Sbjct: 868  GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPV 927

Query: 476  GYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-------------NGTEGFP 522
            G+ G +GPPG  G  G PG  G  G+ G  G+ G  GP G              G  G P
Sbjct: 928  GFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHP 987

Query: 523  GFPGYPGNRGAPGI---NGTKGYP---GLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGP 576
            G PG PG +G PG     G KG P   G+ G +G AG  G       P G +GA G +G 
Sbjct: 988  GPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLP-GAQGAPGLKGG 1046

Query: 577  EGPQGPPGHQGPPG 590
            EGPQGPPG  G PG
Sbjct: 1047 EGPQGPPGPVGSPG 1060



 Score =  278 bits (710), Expect = 2e-74
 Identities = 159/350 (45%), Positives = 190/350 (54%), Gaps = 23/350 (6%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
           G PGL GD G  GERG  G PG  G+ G  G  G++GP   +G+ GE G RG  G RG  
Sbjct: 604 GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP---RGLPGEAGPRGLLGPRGTP 660

Query: 317 GYKGEKGKRGIDGVDGVKGEMG---YPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEK 373
           G  G+ G  G+DG  G KG MG    PG PG +G+PG  G+ GP GP G PG  G +G+ 
Sbjct: 661 GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP 720

Query: 374 GE---PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGER 430
           G    PGADG  G PG  G SG++G  G PGP G  G  G  G  G DG  G +G  GE+
Sbjct: 721 GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK 780

Query: 431 GPRGTPG------TRGPRGDPGEAGPQGDQGREGP---VGVPGDPGEAGPIGPKGYRGDE 481
           G  G PG       +G RG+ G+ GP+G+ G EGP    G  GDPG +G  G KG  G  
Sbjct: 781 GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP 840

Query: 482 GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTK 540
           G PG  G +G  G  G PG PG  GE+G  G AG  G  G  G  G  G+RGA G  G  
Sbjct: 841 GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKP 900

Query: 541 GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           G  G  G +G  G PG+      P+G +G  G+ GP+GP GPPG  G PG
Sbjct: 901 GPKGTSGGDGPPGPPGER----GPQGPQGPVGFPGPKGPPGPPGKDGLPG 946



 Score =  277 bits (709), Expect = 3e-74
 Identities = 157/344 (45%), Positives = 182/344 (52%), Gaps = 21/344 (6%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            RGP G +G  GF G +G PG PG+ G    PG PG  G  G+QG  G  G  G  G +GP
Sbjct: 918  RGPQGPQGPVGFPGPKGPPGPPGKDGL---PGHPGQRGETGFQGKTGPPGPGGVVGPQGP 974

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375
             G  G  G+RG  G  G  GE G PG  G +G+ G  G QG  G  G  G  G  GE+G 
Sbjct: 975  TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL 1034

Query: 376  PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGD---EGNPGPDGAPG---ERGGPGE 429
            PGA G  G  G  GP G  G  G PG  G  G AG     G PGP G PG   E+G PGE
Sbjct: 1035 PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1094

Query: 430  RGPRGTPG---TRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGS 486
            +GP+G  G    +GP G PG AGP G  G +G  G  G+PG+ G  G KG  G  GPPG 
Sbjct: 1095 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1154

Query: 487  EGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLK 546
            +G  GAPG AG  G+PG  G++G  G  G+  EG  GFPG PG  G  G+ G  G  G  
Sbjct: 1155 QGPVGAPGIAGGDGEPGPRGQQGMFGQKGD--EGARGFPGPPGPIGLQGLPGPPGEKGEN 1212

Query: 547  GDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
            GD G  G PG       P G +G +G  G +GPQGPPG  G  G
Sbjct: 1213 GDVGPMGPPG-------PPGPRGPQGPNGADGPQGPPGSVGSVG 1249



 Score =  276 bits (705), Expect = 9e-74
 Identities = 161/369 (43%), Positives = 187/369 (50%), Gaps = 36/369 (9%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            RG PG +G PG +G  G  G PG  G  G+ G  G  GP+G   + G  G +G  G  G 
Sbjct: 1032 RGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIG---LPGRPGPQGPPGPAGE 1088

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGP---PGPKGDPGAFGLKGE 372
            KG  GEKG +G  G DGV+G +G PG  G  GSPG DG +G    PG KG  G  G  G 
Sbjct: 1089 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP 1148

Query: 373  KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGP 432
             G PG  G  G PG +G  G+ G  G+ G  G+KG+ G  G PGP G  G +G PG  G 
Sbjct: 1149 PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1208

Query: 433  RGTPGTRGPRGDPGEAGPQGDQ---GREGPVGVP------------GDPGEAGPIGPKGY 477
            +G  G  GP G PG  GP+G Q   G +GP G P            G+PGEAG  GP G 
Sbjct: 1209 KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1268

Query: 478  RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGI 536
             G  GP G  G +G  GP G  G PG  G  G+DGP GN G  GFPG PG PG  G  G 
Sbjct: 1269 AGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQ 1328

Query: 537  NGT---------KGYPGLKGDEGEAGDPGDDNNDIAP-----RGVKGAKGYRGPEGPQGP 582
            +G           G PG  G  GEAG PG       P      G +G KG +G  G +GP
Sbjct: 1329 DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP 1388

Query: 583  PGHQGPPGP 591
            PG  GP GP
Sbjct: 1389 PGKTGPVGP 1397



 Score =  275 bits (704), Expect = 1e-73
 Identities = 156/351 (44%), Positives = 182/351 (51%), Gaps = 30/351 (8%)

Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
           RG PG  G PG  G  G PG  G  G  G+PG PG  G  G QG+ G +G  G  G +GP
Sbjct: 657 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 716

Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGL------ 369
           +G  G  G  G DG  G  G+ G  G  G  G PG  G  G PGP+G  GA G+      
Sbjct: 717 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 776

Query: 370 KGEKGE---PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGG 426
           KGEKGE   PG  G+ G  G  G  G  G  GE GP G KG AG  G+PGP G  GE+G 
Sbjct: 777 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 836

Query: 427 PGERGPRGTPGTRGPRGD---PGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGP 483
            G  G  G PG +GP+G    PG  G  G++G  G  G PG  G+ GP GP+G RG  GP
Sbjct: 837 LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 896

Query: 484 PGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYP 543
            G  G +G  G  GPPG PG  G +G  GP         GFPG  G  G PG +G  G+P
Sbjct: 897 TGKPGPKGTSGGDGPPGPPGERGPQGPQGPV--------GFPGPKGPPGPPGKDGLPGHP 948

Query: 544 GLKGD---EGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
           G +G+   +G+ G PG       P GV G +G  G  GP G  GH GPPGP
Sbjct: 949 GQRGETGFQGKTGPPG-------PGGVVGPQGPTGETGPIGERGHPGPPGP 992



 Score =  266 bits (681), Expect = 6e-71
 Identities = 165/398 (41%), Positives = 193/398 (48%), Gaps = 59/398 (14%)

Query: 253 QPARGPPGL--RGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310
           +PA   PG+   G PG  G  G  G PG +G  G PG PGD GP G  G+ G  G  G  
Sbjct: 430 EPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPP 489

Query: 311 GSR-------GPKGYKGE--------------------KGKRGIDGVDGVKGEMGYPGLP 343
           G+        G  G KG                     +G  G  G+ G  G +G PG  
Sbjct: 490 GTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSS 549

Query: 344 GCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPP 403
           G KG  G  G QGP G +G PG  G  G++G PGADG  G PG  G  GD G  G PG P
Sbjct: 550 GAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLP 609

Query: 404 GEKGEAGDEGNPGPDGAPGE---RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPV 460
           G+KG  G+ G  GP G PG+   RG  GE GPRG PG  GPRG  G  G  G  G+ G  
Sbjct: 610 GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 669

Query: 461 GVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTE 519
           GV G PG  G +GP+G  G  G  G+ G +G PGP GP G PG  G +G+ G AG  G +
Sbjct: 670 GVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 729

Query: 520 GFPGFP---------------------GYPGNRGAPGINGTKGYPGLKGDEGEAGDPG-- 556
           G PG P                     GYPG RG  G +G +G  G KG++GE G PG  
Sbjct: 730 GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 789

Query: 557 DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGP---PGP 591
            D      RG  G  G RG +GP+GP G  GP   PGP
Sbjct: 790 GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 827



 Score =  246 bits (629), Expect = 6e-65
 Identities = 139/295 (47%), Positives = 167/295 (56%), Gaps = 14/295 (4%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGE---KGSRGEKGS 312
            +G PG  G+PG  GE G  G  GE+GE G+ G PG  GP G +G  G+   KG+ G  G 
Sbjct: 1254 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1313

Query: 313  RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372
             G  G  GE G  G DGV G KGE G PG PG  G  G  G  GPPG +G PGA G +G 
Sbjct: 1314 PGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGR 1373

Query: 373  KGEPGADGEAGR---PGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGE 429
            +GE GA GEAG    PG +GP G +G  G+PGP G +G  G  G  G  GA G+ G PG 
Sbjct: 1374 QGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGP 1433

Query: 430  RGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGA 489
             GP G PG +G   DPG    +G++G  G +G+ G PGE G  G +G  G +G PG++G 
Sbjct: 1434 MGPPGLPGLKG---DPGS---KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGD 1487

Query: 490  RGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPG 544
             G PGPAGP G PG  G  G  GP GN  +G  G  G  G+ G PG  G+ G PG
Sbjct: 1488 GGIPGPAGPLGPPGPPGLPGPQGPKGN--KGSTGPAGQKGDSGLPGPPGSPGPPG 1540



 Score =  225 bits (573), Expect = 2e-58
 Identities = 118/255 (46%), Positives = 138/255 (54%), Gaps = 9/255 (3%)

Query: 255  ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGE----- 309
            A GPPG +G PG +G +G PG  G  G+ G PG PG  G  G  G KGE G  G+     
Sbjct: 1289 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1348

Query: 310  -KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFG 368
              G  GP G  G++G  G  G +G +GE G  G  G +G PG  G  GP GP G PG  G
Sbjct: 1349 PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEG 1408

Query: 369  LKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPG 428
            L+G  G  G  G  G  G  GP G  G PG PG  G+ G  G++G+PG  G  G  G  G
Sbjct: 1409 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG 1468

Query: 429  ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEG 488
            E+G RG PGT   +G PG  G  G  G  GP+G PG PG  GP GPKG +G  GP G +G
Sbjct: 1469 EKGDRGLPGT---QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG 1525

Query: 489  ARGAPGPAGPPGDPG 503
              G PGP G PG PG
Sbjct: 1526 DSGLPGPPGSPGPPG 1540



 Score =  213 bits (541), Expect = 1e-54
 Identities = 151/380 (39%), Positives = 175/380 (46%), Gaps = 70/380 (18%)

Query: 273 KPGLPGEKGEAGDPGRPGDLG----PVGYQGMKGEKGSRGE----------KGSRGPKGY 318
           KP  P    E   PG P +       +   G  GEKG +GE          +G  GP G 
Sbjct: 392 KPTSP--PNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGP 449

Query: 319 KGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD-PGAFGLKGEKGEPG 377
            G  G  G+ G  G  G+ G  G PG  G PG DG+ GPPG     P  +G  G KG   
Sbjct: 450 AGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTI 509

Query: 378 ADGEA--------------GRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGE 423
           +  EA              G PG  G +G  G  G PG  G KGE+GD G  GP G  G 
Sbjct: 510 SAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGP 569

Query: 424 RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGP 483
            G  G+ G RG PG  G RG PGE G +GD+G +G  G+PGD G       +G RG +GP
Sbjct: 570 PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGH------RGERGPQGP 623

Query: 484 PGSE------------GARGAPGPAGP------------PGDPGLMGERGEDGPAGN-GT 518
           PG              G RG PG AGP            PG PG+ G  G  GP GN G 
Sbjct: 624 PGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGP 683

Query: 519 EGFPGFPGY---PGNRGAPGINGTKGYPGLKGDEGE---AGDPGDDNNDIAP--RGVKGA 570
           +G PG PG    PG +G PG  G  G PG KG +G+   AG PG D     P   G  G 
Sbjct: 684 QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGE 743

Query: 571 KGYRGPEGPQGPPGHQGPPG 590
           KG  GP GPQGP G+ GP G
Sbjct: 744 KGALGPPGPQGPIGYPGPRG 763



 Score =  194 bits (493), Expect = 4e-49
 Identities = 107/224 (47%), Positives = 126/224 (56%), Gaps = 21/224 (9%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP---VGYQGMKGEKGSRGEKGSR 313
            G  G+ GD G +G+ G+PG PG  GEAG PG PG  GP    G +G +GEKG++GE G+ 
Sbjct: 1327 GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAE 1386

Query: 314  GPKGY------KGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAF 367
            GP G       +G  GK G +G+ G+ G +G  GLPG  G    DG  GP GP G PG  
Sbjct: 1387 GPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ---DGPPGPMGPPGLPGLK 1443

Query: 368  ---GLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGER 424
               G KGEKG PG  G  G PG  G  GD G PG  G PG KG+ G  G  GP G PG  
Sbjct: 1444 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP 1503

Query: 425  GGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGE 468
            G PG +GP+G  G+ GP      AG +GD G  GP G PG PGE
Sbjct: 1504 GLPGPQGPKGNKGSTGP------AGQKGDSGLPGPPGSPGPPGE 1541



 Score =  157 bits (398), Expect = 4e-38
 Identities = 99/238 (41%), Positives = 114/238 (47%), Gaps = 31/238 (13%)

Query: 365 GAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE--PGPPGEKGEAGDEGNPGPDGAPG 422
           GA+G KG+KGEP                   +PG    GPPG  G AG  G PG  G  G
Sbjct: 420 GAYGEKGQKGEPAVV----------------EPGMLVEGPPGPAGPAGIMGPPGLQGPTG 463

Query: 423 ERGGPGERGPRGTPGTRGPRGDPGEAGPQ-------GDQGREGPVGVPGDPGEAGPIGPK 475
             G PG+RGP G PG  G  G PG  G         G  G +GP  +     +A  I  +
Sbjct: 464 PPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPT-ISAQEAQAQAILQQ 522

Query: 476 GYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAP 534
                 GPPG  G  G PGP G PG  G  GE G+ GP G  G +G PG  G PG RG P
Sbjct: 523 ARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRP 582

Query: 535 GINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592
           G +G +G PG   + G  GD G D     P G KG +G RGP+GP GPPG  G  G D
Sbjct: 583 GADGGRGMPG---EPGAKGDRGFDGLPGLP-GDKGHRGERGPQGPPGPPGDDGMRGED 636



 Score =  103 bits (258), Expect = 6e-22
 Identities = 61/141 (43%), Positives = 73/141 (51%), Gaps = 24/141 (17%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            GPPG  G PG  G +G PG    KGE G PG  G +GP G QG KG++G  G +GS    
Sbjct: 1429 GPPGPMGPPGLPGLKGDPG---SKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGS---- 1481

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376
                           G KG+ G PG  G  G PG  G+ GP GPKG+ G+ G  G+KG+ 
Sbjct: 1482 --------------PGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDS 1527

Query: 377  GADGEAGRPGSSGPSGDEGQP 397
            G  G    PGS GP G+  QP
Sbjct: 1528 GLPGP---PGSPGPPGEVIQP 1545


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score =  301 bits (770), Expect = 3e-81
 Identities = 164/344 (47%), Positives = 195/344 (56%), Gaps = 29/344 (8%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            G PGL G PG +G  G+PGL G KGE GDPGRPG   PVG QG  G  G  GE G  G K
Sbjct: 955  GAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPG---PVGEQGFMGFIGLVGEPGIVGEK 1011

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376
            G   ++G  G  GV G KG MG+PG+PG  G+PG  G QGPPG +G PG  G KG +G  
Sbjct: 1012 G---DRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPR 1068

Query: 377  GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGN---------PGPDGAPGERGGP 427
            G DG AG  GS G  G  G  G PG PG++G AG+ G+         PGP G PG +G P
Sbjct: 1069 GPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLP 1128

Query: 428  GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487
            GE GP+   G +GP G PGE GP+G  G  G  G+PG+ G  G +GP G  G++G  G  
Sbjct: 1129 GEPGPQ---GPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQR 1185

Query: 488  GARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGTKGYPGLK 546
            G  G  G +GP G  GL G+RG+ GP G +G +G  G  G  G  G PG+ G +G  G  
Sbjct: 1186 GEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKS 1245

Query: 547  GDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
            G +GE G            G KGAKGY+G  G  G PG  GPPG
Sbjct: 1246 GKQGEKG----------RTGAKGAKGYQGQLGEMGVPGDPGPPG 1279



 Score =  288 bits (738), Expect = 1e-77
 Identities = 177/399 (44%), Positives = 203/399 (50%), Gaps = 66/399 (16%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKG------------EK 304
            GPPG+ G  G  G  G PG  G  GE G  G PG  GP G +G KG            E+
Sbjct: 1018 GPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQ 1077

Query: 305  GSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDP 364
            GSRG KG  GP+G  G  G++G+ G  G  G  G+PG+PG  G PG  G+ G PGP+G  
Sbjct: 1078 GSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQ 1137

Query: 365  GAFGLKGE---KGEPGADGEAGRPGSSGPSGD------------EGQPGEP------GPP 403
            G  G  GE   KG PGA GE G PG +G  GD             GQ GEP      GP 
Sbjct: 1138 GPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPM 1197

Query: 404  GEKGEAGDEGNPGPDGAPGERGGP---GERGPRGTPGTRGPRGDPGEAGPQGDQGRE--- 457
            G  G  GD G+PGPDG  GE+G     GE GP G PG  G RG  G++G QG++GR    
Sbjct: 1198 GPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAK 1257

Query: 458  ---------GPVGVPGDPGEAGPIGPKGYRGDEGP---PGSEGARGAP------------ 493
                     G +GVPGDPG  G  GPKG RG  GP   PG  GA+G P            
Sbjct: 1258 GAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIV 1317

Query: 494  GPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAG 553
            GP GPPG  G  GE+GEDG A  G  G PG  G  G+RG  G  G  GYPG +G +G  G
Sbjct: 1318 GPLGPPGPKGEKGEQGEDGKA-EGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRG 1376

Query: 554  DPGDDN--NDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
             PG         PRG  G KG +G EGP+G  G  G PG
Sbjct: 1377 KPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPG 1415



 Score =  287 bits (735), Expect = 3e-77
 Identities = 160/375 (42%), Positives = 196/375 (52%), Gaps = 39/375 (10%)

Query: 256  RGPPGLRGDPGFEGERGK---PGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312
            +G PG+ GDPGF+G++G    PG PG +G+ G  G+ GD G +G+ G  G +G  G+ G 
Sbjct: 858  QGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGP 917

Query: 313  RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372
             G  G +G KGK G  G+ G +G++G  G  G  G PG  G++G PG KG PG  GL G 
Sbjct: 918  PGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGV 977

Query: 373  KGEPGADGE---------------AGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEG---- 413
            KGEPG  G                 G PG  G  GD G  G PG PG KG  G  G    
Sbjct: 978  KGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGG 1037

Query: 414  -----NPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGE 468
                  PGP G PG RG PG RG +G  G RGP G  GE G +G +G  GP G PG PG+
Sbjct: 1038 MGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQ 1097

Query: 469  AGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGF 524
             G  G +G+ G  G PG  G  G PG  G PG+PG  G +G  GP G     G  G  G 
Sbjct: 1098 QGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGE 1157

Query: 525  PGYPGNRGAPGINGTKGYPGLKGDEGEAGDPG--DDNNDIAPRGVKGAKGYRGPEGPQGP 582
            PG PG  G  G  G  G PG +G  G+ G+PG   D+  + P G+KG +G  GP+G  G 
Sbjct: 1158 PGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGE 1217

Query: 583  PGHQ------GPPGP 591
             G +      GPPGP
Sbjct: 1218 KGQEGLMGEDGPPGP 1232



 Score =  284 bits (727), Expect = 3e-76
 Identities = 167/385 (43%), Positives = 195/385 (50%), Gaps = 49/385 (12%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            +G  G+ G PG  G +G  G PG  G  G PG PG  GP G +G  G +G++G +G RGP
Sbjct: 1011 KGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGP 1070

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGF---DGIQGPPGPKGDPGAFGLKGE 372
             G  GE+G RG+ G  G +G  G PG  G  G  G     G  G PGP G PG  GL GE
Sbjct: 1071 DGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGE 1130

Query: 373  KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGE---KGEAGDEGNPGPDGAPGERGGP-- 427
             G  G  G  G PG  GP G  G  GEPG PGE   KG+ G  G PG  G  G+RG P  
Sbjct: 1131 PGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGL 1190

Query: 428  -GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPV---GVPGDPGEAGPIGPKGYRGDEGP 483
             G+ GP G  G +G RGDPG  G  G++G+EG +   G PG PG  G  GP+G  G +G 
Sbjct: 1191 EGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGE 1250

Query: 484  PGSEGARGA------------PGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFPGY 527
             G  GA+GA            PG  GPPG PG  G RG  GP G     G +G PG  GY
Sbjct: 1251 KGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGY 1310

Query: 528  PGNR------GAPGINGTKGY----------PGLKGDEGEAGDPGD--DNNDIAPRGVKG 569
             G++      G PG  G KG           PG  GD G  GD GD  +  D    G +G
Sbjct: 1311 DGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEG 1370

Query: 570  AKGYRGPEGPQGPPGHQGP---PGP 591
             +G RG  G QG PGH GP   PGP
Sbjct: 1371 VQGLRGKPGQQGQPGHPGPRGWPGP 1395



 Score =  283 bits (723), Expect = 8e-76
 Identities = 168/392 (42%), Positives = 203/392 (51%), Gaps = 57/392 (14%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDP---------------GRPGDL---GPVGYQ 298
            G PGL G PG +GERG PG+PG++G+ G P               G PG+L   GP G  
Sbjct: 760  GLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVP 819

Query: 299  GMKGEKGSRGEKGSRGPKGYK---------GEKGKRGIDGVDGVKGEMGYPGLPGCKGSP 349
            G+ G+ G  G  G  GPKG K         G KG +G  GV GV G+ G+ G  G +G P
Sbjct: 820  GLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLP 879

Query: 350  GFDGIQGPPGP---KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE---PGPP 403
            GF G +G PGP    GD G+ G  G  G  G  G+ G PG +GP G +G+PG    PGP 
Sbjct: 880  GFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPR 939

Query: 404  GEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP---GTRGPRGDPGEAGPQGDQGREGPV 460
            G+ G  GDEG  GP GAPG  G PG +G  G P   G +G  GDPG  GP G+QG  G +
Sbjct: 940  GQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFI 999

Query: 461  GVPGDP------------GEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGD---PGLM 505
            G+ G+P            G  G  GPKG  G  G PG  G  G PGP GPPG    PG+ 
Sbjct: 1000 GLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMR 1059

Query: 506  GERGEDGPAG----NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNND 561
            G +G  GP G     G +G  G  G PG +G PG  G +G  G +G  G  G PG     
Sbjct: 1060 GAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPS 1119

Query: 562  IAP--RGVKGAKGYRGPEGPQGPPGHQGPPGP 591
              P  +G+ G  G +GP+GP GPPG  GP GP
Sbjct: 1120 GPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGP 1151



 Score =  280 bits (717), Expect = 4e-75
 Identities = 170/389 (43%), Positives = 199/389 (51%), Gaps = 57/389 (14%)

Query: 257  GPPGLRGDPGFEG------ERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310
            GPPG +G  G+ G      E+G+PG  G  G  G PGR G  GPV   G  G KGSRG  
Sbjct: 703  GPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPV---GDPGPKGSRGYI 759

Query: 311  GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGC---KGSPGFDGIQGP---PGPKGDP 364
            G  G  G  G  G+RG+ GV G +G+MG PG PG    +G PG DG  G    PGP G P
Sbjct: 760  GLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVP 819

Query: 365  ---------GAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP 415
                     G  G  G KG  G  G  G PG  G  G++G PG  G PG +G+ G +G P
Sbjct: 820  GLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLP 879

Query: 416  GPDGA---PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGD---PGEA 469
            G  GA   PG  G  G++G  G PG  GP G PG+ GP GD G EG  G PG    PG  
Sbjct: 880  GFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPR 939

Query: 470  GPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN----GTEGFPGF- 524
            G +GP+G  G  GPPG+ G  G PG  G PG PGL G +GE G  G     G +GF GF 
Sbjct: 940  GQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFI 999

Query: 525  -----PGYPGNR---------GAPGINGTKGYPGLKGDEGEAGDPGDDN--NDIAPRGVK 568
                 PG  G +         G PG  G+ G+PG+ G  G  G+PG         P G++
Sbjct: 1000 GLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMR 1059

Query: 569  GAKGYRGPEGPQGPPGHQ------GPPGP 591
            GAKG RGP GP GP G Q      GPPGP
Sbjct: 1060 GAKGRRGPRGPDGPAGEQGSRGLKGPPGP 1088



 Score =  280 bits (717), Expect = 4e-75
 Identities = 166/379 (43%), Positives = 198/379 (52%), Gaps = 43/379 (11%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            RGP G  G  G +G  G  G  G +G+ G+ G PGD GP G  G KG +GS G  G+ G 
Sbjct: 1239 RGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGR 1298

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDG-IQGPPGPKGDPGAFGLKGEKG 374
             G +GE G  G DG  G+ G +G PG  G KG  G DG  +GPPGP GD G  G +G++G
Sbjct: 1299 MGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRG 1358

Query: 375  EPGADGEAGRPGSSG---PSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERG 431
            EPG  G  G+ G  G     G +GQPG PGP G  G  G +G  GP G  G+ G PG RG
Sbjct: 1359 EPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRG 1418

Query: 432  PRGTPGTRGPRGDPGE------AGPQGDQGREGPVGVPG---DPGEAGPIGPKGYRGD-- 480
             +G  G  GPRG  G       AGP G  GR+G  G  G   D G+ GP+GP G RG+  
Sbjct: 1419 VQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPG 1478

Query: 481  -------EGPPGSEGARGAPGPAGPPGD---------PGLMGERGEDG-PAGNGTEGFPG 523
                   +GPPG +G  G PG  GPPG          PG  GE G  G P  +G  GFPG
Sbjct: 1479 VAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPG 1538

Query: 524  FPGYPGNRGAPG------INGTKGYPGLKGDEGEAGDPG--DDNNDIAPRGVKGAKG--- 572
              G  G +G PG      I G +G PGL G EG  G  G    +    P+G KG++G   
Sbjct: 1539 MAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWG 1598

Query: 573  YRGPEGPQGPPGHQGPPGP 591
             +GP GP GP G  GPPGP
Sbjct: 1599 LQGPRGPPGPRGRPGPPGP 1617



 Score =  276 bits (707), Expect = 5e-74
 Identities = 158/364 (43%), Positives = 198/364 (54%), Gaps = 29/364 (7%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            +GPPG +G PG  G++G  G  G  G  G PG PG  GP G +G+ GE G +G +G  GP
Sbjct: 1083 KGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGP 1142

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGI---QGPPGPKGDPGAFG---L 369
             G  G KG  G  G  G+ GE G  G  G  G+PG  G+   +G PG +GD G  G   L
Sbjct: 1143 PGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGL 1202

Query: 370  KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPG------PPGEKGEAGDEGNPGPDGAPG- 422
            KG++G+PG DGE G  G  G  G++G PG PG      P G+ G+ G++G  G  GA G 
Sbjct: 1203 KGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGY 1262

Query: 423  -----ERGGPGERGPRGTPGTRGPRGD---PGEAGPQGDQGREGPVGVPGDPGEAGPIGP 474
                 E G PG+ GP GTPG +G RG     G  G  G QG  G  G  G  G  GP+GP
Sbjct: 1263 QGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGP 1322

Query: 475  KGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN----GTEGFPGFPGYPGN 530
             G +G++G  G +G   A GP GPPGD G +G+RG+ G  G+    G EG  G  G PG 
Sbjct: 1323 PGPKGEKGEQGEDGK--AEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQ 1380

Query: 531  RGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAP--RGVKGAKGYRGPEGPQGPPGHQGP 588
            +G PG  G +G+PG KG +G  G  G      AP  RGV+G +G  GP G  G  G +G 
Sbjct: 1381 QGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGI 1440

Query: 589  PGPD 592
             GPD
Sbjct: 1441 AGPD 1444



 Score =  274 bits (701), Expect = 3e-73
 Identities = 181/433 (41%), Positives = 199/433 (45%), Gaps = 99/433 (22%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGD---------LGPVGYQGMKGEKGS 306
            RG  G+ G PG  GERG PGL G  GE G PG PG          LGP+GY G KG KG 
Sbjct: 783  RGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGL 842

Query: 307  RGEKGSRGPKGYKGEKGKRGIDG---VDGVKGEMGYPGLPGCKGSPG---------FDGI 354
             G  G  G KG KGE+G  G+ G     G KG  G PG PG +G PG           G 
Sbjct: 843  MGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGF 902

Query: 355  QGPPGPKGDPGAFGLKGE------KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPG---- 404
             GPPGP+G PG  G  G+      KG+PGA G  G  G  GP GDEG  G PG PG    
Sbjct: 903  PGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQ 962

Query: 405  --------------EKGEAGDEGNPGPDGA------------PGERGGPGERGPRGTPGT 438
                           KGE GD G PGP G             PG  G  G+RG  G PG 
Sbjct: 963  PGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGV 1022

Query: 439  RGPRGD------------PGEAGPQGDQGREGPVGVPGDPGEAGPIGP------KGYRGD 480
             GP+G             PGE GPQG  G  GP G+ G  G  GP GP      +G RG 
Sbjct: 1023 PGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGL 1082

Query: 481  EGPP---------------------GSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTE 519
            +GPP                     GS G  G PGP+GPPG  GL GE G  GP   G  
Sbjct: 1083 KGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGP--QGPI 1140

Query: 520  GFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGP 579
            G PG  G  G  GA G  G  G  G+KGD G  G PG+    I  RG  G +G  GP GP
Sbjct: 1141 GPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGL-IGQRGEPGLEGDSGPMGP 1199

Query: 580  QGPPGHQGPPGPD 592
             G  G +G PGPD
Sbjct: 1200 DGLKGDRGDPGPD 1212



 Score =  273 bits (697), Expect = 8e-73
 Identities = 158/363 (43%), Positives = 185/363 (50%), Gaps = 28/363 (7%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGY---QGMKGEKGSRGEKGS 312
            +GP G  G PG  G +G PG  GE G  G+ G  GDLGP+G    QG+ G++G  G +G 
Sbjct: 1134 QGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGD 1193

Query: 313  RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372
             GP G  G KG RG  G DG  GE G  GL G  G PG  G+ G  GP+G  G  G KG 
Sbjct: 1194 SGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGR 1253

Query: 373  KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGP 432
             G  GA G  G+ G  G  GD G PG PGP G +G  G  G PG  GA GE G  G  G 
Sbjct: 1254 TGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGH 1313

Query: 433  RGTPGTRGPRGDPGEAGPQGDQGR-EGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGA-- 489
            +G  G  GP G  GE G QG+ G+ EGP G PGD G  G  G +G  GD G PG EG   
Sbjct: 1314 KGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQG 1373

Query: 490  -------RGAPGPAGPPGDPGLMGERGEDGPAG-------------NGTEGFPGFPGYPG 529
                   +G PG  GP G PG  G +G +GP G              G +G PG  G  G
Sbjct: 1374 LRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVG 1433

Query: 530  NRGAPGINGTKGYPGLKGDEGEAGDPGDDNN--DIAPRGVKGAKGYRGPEGPQGPPGHQG 587
             +G  GI G  G PG  G  G+ G+ GDD +   + P G +G  G  G  G QGPPG +G
Sbjct: 1434 RQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKG 1493

Query: 588  PPG 590
              G
Sbjct: 1494 ESG 1496



 Score =  270 bits (689), Expect = 7e-72
 Identities = 173/421 (41%), Positives = 194/421 (46%), Gaps = 87/421 (20%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVG---------YQGMKGEKGSR 307
            GPPGL G PG  G RG  G PG  G  G PG PG  G  G         + G KG+ G  
Sbjct: 637  GPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLP 696

Query: 308  GEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGP---PGPKGDP 364
            G  G+ GP G KG KG  G  G  G +G+ G  G PG KG PG  G+ GP   PGPKG  
Sbjct: 697  GLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSR 756

Query: 365  GAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPG------PPGEKGEAGDEGNPGPD 418
            G  GL G  G PG+DGE G PG  G  G  G PG PG      PPG  G  G+ G PGP 
Sbjct: 757  GYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPP 816

Query: 419  GAPGERGGPGERGPRGTPGTRGPRG---DPGEAGPQGDQGREGPVGVPGDPG-------- 467
            G PG  G  G  GP G PG +G +G     GE G +GD+G +G  GV GDPG        
Sbjct: 817  GVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQ 876

Query: 468  ----------EAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-- 515
                      + GP+G  G +G  G PG  G  G PG  GPPGD G  G +G+ G  G  
Sbjct: 877  GLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLP 936

Query: 516  --------NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPG----------- 556
                     G EG  G PG PG  G PG  G  G PGL G +GE GDPG           
Sbjct: 937  GPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFM 996

Query: 557  ---------------DDNNDIAPRGVKGAKGYR------------GPEGPQGPPGHQGPP 589
                            D   + P GV G KG              G  GPQGPPG +GPP
Sbjct: 997  GFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPP 1056

Query: 590  G 590
            G
Sbjct: 1057 G 1057



 Score =  266 bits (680), Expect = 7e-71
 Identities = 159/379 (41%), Positives = 198/379 (52%), Gaps = 52/379 (13%)

Query: 253  QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312
            Q  +G  G +G  G++G+ G+ G+PG+ G  G P            G KG +GS G  G+
Sbjct: 1248 QGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTP------------GPKGSRGSLGPTGA 1295

Query: 313  RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDG-IQGPPGPKGDPGAFGLKG 371
             G  G +GE G  G DG  G+ G +G PG  G KG  G DG  +GPPGP GD G  G +G
Sbjct: 1296 PGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRG 1355

Query: 372  EKGEPGADGEAGRPGSS---GPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPG 428
            ++GEPG  G  G+ G     G  G +GQPG PGP G  G  G +G  GP G  G+ G PG
Sbjct: 1356 DRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPG 1415

Query: 429  ERGPRGTPGTRGPRGDPGE------AGPQGDQGREGPV---GVPGDPGEAGPIGPKGYRG 479
             RG +G  G  GPRG  G       AGP G  GR+G     G  GD G+ GP+GP G RG
Sbjct: 1416 RRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRG 1475

Query: 480  D---------EGPPGSEGARGAPGPAGPPGD------PGLMGERGEDG----PAGNGTEG 520
            +         +GPPG +G  G PG  GPPG        GL G +GE G    P  +G  G
Sbjct: 1476 NPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMG 1535

Query: 521  FPGFPGY------PGNRGAPGINGTKGYPGLKGDEGEAGDPG--DDNNDIAPRGVKGAKG 572
            FPG  G       PG+ G  GI G +G PGL G EG  G  G    +    P+G KG++G
Sbjct: 1536 FPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRG 1595

Query: 573  YRGPEGPQGPPGHQGPPGP 591
              G +GP+GPPG +G PGP
Sbjct: 1596 DWGLQGPRGPPGPRGRPGP 1614



 Score =  259 bits (661), Expect = 1e-68
 Identities = 151/341 (44%), Positives = 176/341 (51%), Gaps = 18/341 (5%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
           GPPG +GD G  G  G PGLPG  G  G  G PG  G  G  G  G KG +G+ G    K
Sbjct: 625 GPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGK 684

Query: 317 GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376
            +            DG KG+MG PGL G  G PG  G +G PGP G PG  G  G +G P
Sbjct: 685 AH------------DGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSP 732

Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436
           GA G  GR G  GP GD G  G  G  G  G  G  G+ G  G PG  G  G+ G  G P
Sbjct: 733 GAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFP 792

Query: 437 GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPA 496
           G  G RG PG  G  G+ G  GP GVPG  G+ G +GP GY G +G  G  G+ G PG  
Sbjct: 793 GVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLK 852

Query: 497 GPPGDPGLMGERGEDGPAGN-GTEGFPGFP---GYPGNRGAPGINGTKGYPGLKGDEGEA 552
           G  G+ G+ G  G+ G  G+ G++G PGFP   G PG  G  G  G+ G+PG  G EG  
Sbjct: 853 GDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFP 912

Query: 553 GD--PGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
           GD  P  DN     +G  GA+G  GP G  GP G +GP GP
Sbjct: 913 GDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGP 953



 Score =  245 bits (625), Expect = 2e-64
 Identities = 140/322 (43%), Positives = 178/322 (55%), Gaps = 23/322 (7%)

Query: 255  ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDL-GPVGYQGMKGEKGSRGEKGSR 313
            A+G PGL G  G +G  G  G PG KGE G+ G  G   GP G  G +G  G RG++G  
Sbjct: 1301 AQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEP 1360

Query: 314  GPKGYKGEKGKRGIDGVDGVKGEMGYPG---LPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370
            G  GY G++G +G+ G  G +G+ G+PG    PG KGS G +G +G  G  G PG  G++
Sbjct: 1361 GDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQ 1420

Query: 371  GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGER 430
            G +G PG  G  GR G  G +G +G PG  G  G++GE GD+G+PGP G  G+RG PG  
Sbjct: 1421 GLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVA 1480

Query: 431  G---PRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487
            G    +G PG +G  G PG+ GP G +G EG  G+PG+ GE G    KG  GD G  G  
Sbjct: 1481 GLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGS---KGQPGDSGEMGFP 1537

Query: 488  GARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGF---------PGFPGYPGNRGAP--- 534
            G  G  GP GPPGD G  G +G  GP G  G EG           G PG  G++G+    
Sbjct: 1538 GMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDW 1597

Query: 535  GINGTKGYPGLKGDEGEAGDPG 556
            G+ G +G PG +G  G  G PG
Sbjct: 1598 GLQGPRGPPGPRGRPGPPGPPG 1619



 Score =  164 bits (416), Expect = 3e-40
 Identities = 120/318 (37%), Positives = 139/318 (43%), Gaps = 96/318 (30%)

Query: 347 GSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEK 406
           GS  F  + GPPGPKGD G                          G  G PG PG PG +
Sbjct: 616 GSTPFPLLMGPPGPKGDCGL------------------------PGPPGLPGLPGIPGAR 651

Query: 407 GEA------GDEGNPGP------------------DGAPGERGGPGERGPRGTPGTRGPR 442
           G        G+ G PGP                  DGA G+ G PG  G  G PG +G +
Sbjct: 652 GPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHK 711

Query: 443 GDPGEAGPQGDQGREGPVGVPGD---------PGEAGPIGPKGYRGD------EGPPGSE 487
           G PG AG  G+QG+ GP G PG          PG  G  GPKG RG        G PGS+
Sbjct: 712 GYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSD 771

Query: 488 GARGAP------GPAGPPGDPGLMGERGEDGPAGN----GTEGFPGFP------------ 525
           G RG P      G  G PG PG+ GERG  G  GN    G  G PG P            
Sbjct: 772 GERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPI 831

Query: 526 GYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNN-----DIAPRGVKGAKGYRGPEGP- 579
           GYPG +G  G+ G+ G PGLKGD+GE G PG   +     D   +G+ G  G RG  GP 
Sbjct: 832 GYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPL 891

Query: 580 -----QGPPGHQGPPGPD 592
                +G  G  GPPGP+
Sbjct: 892 GKVGDKGSIGFPGPPGPE 909



 Score =  163 bits (413), Expect = 7e-40
 Identities = 97/220 (44%), Positives = 112/220 (50%), Gaps = 12/220 (5%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            +G  G  G PG  G +G  GLPG +G  G  G  G  GP G  G  G+ G +GE+G  G 
Sbjct: 1405 KGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGD 1464

Query: 316  KGYKGEKGKRGIDGVDGV---------KGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366
             G  G  GKRG  GV G+         KGE G PG  G  G  G +G  G PG +G+PG+
Sbjct: 1465 PGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGS 1524

Query: 367  FGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGG 426
             G  G+ GE G  G AG  G  GP GD G  G  GP G  G  G EG  GP G  G  G 
Sbjct: 1525 KGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGL 1584

Query: 427  PGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDP 466
            P   GP+G  G+RG  G  G  GP G +GR GP G PG P
Sbjct: 1585 P---GPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGP 1621



 Score =  159 bits (403), Expect = 1e-38
 Identities = 102/290 (35%), Positives = 124/290 (42%), Gaps = 86/290 (29%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGE---------KGEAGDPGRPGDLGPVGYQGMKGEKGSR 307
            GPPG RG  G  G+RG+PG PG          +G+ G  G+PG  GP G+ G KG KG+ 
Sbjct: 1343 GPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAE 1402

Query: 308  GEKGSRG------------------PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSP 349
            G KG +G                  P+G  G +G  GI G DG+ G  G  G  G +G  
Sbjct: 1403 GPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDD 1462

Query: 350  GFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEA 409
            G  G  GP G +G+PG  GL G +G PG  GE+G PG  GP G  G  G  G PG +GE 
Sbjct: 1463 GDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEP 1522

Query: 410  GDEGNPG---------------PDGAPGERGGPGERGPRGTPGTRG-------------- 440
            G +G PG               P G PG+ G  G +GPRG PG  G              
Sbjct: 1523 GSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPS 1582

Query: 441  -------------------------PRGDPGEAGPQGDQGREGPVGVPGD 465
                                     PRG PG  GP G     GP+ +  D
Sbjct: 1583 GLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPG-----GPIQLQQD 1627



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 32/80 (40%), Positives = 38/80 (47%), Gaps = 18/80 (22%)

Query: 253  QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312
            Q  RGPPGL G  G  G                    G LGP G  G KG+KGSRG+ G 
Sbjct: 1558 QGPRGPPGLMGKEGIVGPL------------------GILGPSGLPGPKGDKGSRGDWGL 1599

Query: 313  RGPKGYKGEKGKRGIDGVDG 332
            +GP+G  G +G+ G  G  G
Sbjct: 1600 QGPRGPPGPRGRPGPPGPPG 1619


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score =  300 bits (769), Expect = 4e-81
 Identities = 161/349 (46%), Positives = 192/349 (55%), Gaps = 20/349 (5%)

Query: 251 ECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310
           +C P  GPPGL G PGF+G++G PG PG +G  G  G  G  G  G  G+ G +GS+GE+
Sbjct: 563 DCPP--GPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGER 620

Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370
           G+ G  G KG++G  G+ G  G  G  G PG  G  G+ G  GIQG PG +G PG  G  
Sbjct: 621 GADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPS 680

Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQPGEPG---------PPGEKGEAGDEGNPGPDGAP 421
           G  G PG +G+ GR G  GP G+ G+ GEPG         PPG KG  GD G PGP G  
Sbjct: 681 GLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGES 740

Query: 422 GERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE 481
           G  G PG+ G  G  G  GP G  G  GP+G  G+ G    PG PGE GP G  G +G +
Sbjct: 741 GAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGS---PGSPGEPGPSGTPGQKGSK 797

Query: 482 GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKG 541
           G  GS G  G  GP GPPG+PG  G  G++G  G      PG PG+ G RG PGI G KG
Sbjct: 798 GENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGK-----PGEPGFKGERGDPGIKGDKG 852

Query: 542 YPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
            PG KG  G+ G PG   +     G +G  G  GP GP GPPG  G PG
Sbjct: 853 PPGGKGQPGDPGIPGHKGH-TGLMGPQGLPGENGPVGPPGPPGQPGFPG 900



 Score =  290 bits (743), Expect = 4e-78
 Identities = 168/379 (44%), Positives = 194/379 (51%), Gaps = 54/379 (14%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAG------DPGRPGDLGPVGYQGMKGEKGSRGEK 310
           G PGLRG PG +GERG+ G  GE+G  G      DPG PG  GP G +G  GE G RG  
Sbjct: 419 GAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSP 477

Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGY--------------PGLPGCKGSPGFDGIQG 356
           G  GP G KG++G  GI G  G +G+ G                G PG +G PGF G QG
Sbjct: 478 GLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQG 537

Query: 357 PPG------------------------PKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSG 392
           P G                        P G PG  GL G KG+ G  G+ GR G+ G  G
Sbjct: 538 PAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKG 597

Query: 393 DEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQG 452
           + G PG PGPPG    AG +G+ G  GA GE G  G++G  G PG  GP G+PG  G  G
Sbjct: 598 EAGPPGLPGPPGI---AGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADG 654

Query: 453 DQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDG 512
             G  GP G+ G PG+ GP GP+G  G  G PG EG  G  G  GPPG+PG  GE G  G
Sbjct: 655 IAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPG 714

Query: 513 PAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKG 572
           P   G  G PGF G+ G+ GAPG  G  G  GL G EG  G  GD      P G +G +G
Sbjct: 715 P--EGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTG----PTGPQGPQG 768

Query: 573 YRGPEGPQGPPGHQGPPGP 591
            RGP G  G PG  G PGP
Sbjct: 769 PRGPPGKNGSPGSPGEPGP 787



 Score =  286 bits (732), Expect = 7e-77
 Identities = 181/442 (40%), Positives = 211/442 (47%), Gaps = 98/442 (22%)

Query: 248 CSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGD---PGRPGDLGPV------GYQ 298
           C    + A G   L G+PG  GE G PG PG +GE G+    GRPG+ G        G+ 
Sbjct: 235 CILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFP 294

Query: 299 GMKGEKGSRGEKGSRGPKGYKGEKGKRG----------------------IDGVDGVKGE 336
           G++GEKG +GEKG  G  G KG++G++G                      + G  G KGE
Sbjct: 295 GVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGE 354

Query: 337 MGYPGL---PGCKGSPGFDGIQ---GPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGP 390
            G PGL   PG +G PG  G Q   GPPG KG  GA G  G  G PGA G  G PG SGP
Sbjct: 355 KGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGP 414

Query: 391 SGDEGQPGEPGPP------GEKGEAGDEGNPGPDGAPGERGGPGERGP--RGTPGTRGPR 442
            G  G PG  G P      GEKG AG+EG+PGP G  G+ G PG  GP  +G  G  G R
Sbjct: 415 PGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLR 474

Query: 443 GDPGEAGPQGDQGREGPVGVPGDPGE--------AGPIGPKGYRGDEGPPGSEGARGAPG 494
           G PG  GP G +G  G  G+PG PG         AGP GP G  GD+G PGS G  G PG
Sbjct: 475 GSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPG 534

Query: 495 ------------------------------PAGPPGDPGLMGERGEDG----PAGNGTEG 520
                                         P GPPG PGL G +G+ G    P   GTEG
Sbjct: 535 PQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEG 594

Query: 521 FPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNN-----------DIAPRGVKG 569
             G  G PG  G PGI G +G  G +G +GE G  GD  +           +  P G  G
Sbjct: 595 KKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADG 654

Query: 570 AKGYRGPEGPQGPPGHQGPPGP 591
             G  GP G QG PG +GPPGP
Sbjct: 655 IAGAAGPPGIQGSPGKEGPPGP 676



 Score =  283 bits (725), Expect = 4e-76
 Identities = 180/435 (41%), Positives = 205/435 (47%), Gaps = 98/435 (22%)

Query: 256 RGPPGLRGDPGFEGERGKPGL---PGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312
           RG  GL G PG  GE G+ GL   PGEKGEAG PG PG  G  G +G +GEKG  G  G 
Sbjct: 255 RGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGL 314

Query: 313 RGPKGYKGEKGKRGIDGVDGV-------------------KGEMGYPGLPGCKGSPGFDG 353
           +G +G KGE G  G  G+ G                    KG+ G PG PG +G PG  G
Sbjct: 315 KGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELG 374

Query: 354 IQGPPGP---KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPG------ 404
            QGP GP   KG  GA G  G  G PGA G  G PG SGP G  G PG  G PG      
Sbjct: 375 PQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERG 434

Query: 405 EKGEAGDEGNPGPDGAPGERGGPGERGP--RGTPGTRGPRGDPGEAGPQGDQGREGPVGV 462
           EKG AG+EG+PGP G  G+ G PG  GP  +G  G  G RG PG  GP G +G  G  G+
Sbjct: 435 EKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGI 494

Query: 463 PGDPGE--------AGPIGPKGYRGDEGPPGSEGARGAPGPAGP---------------- 498
           PG PG         AGP GP G  GD+G PGS G  G PGP GP                
Sbjct: 495 PGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDIN 554

Query: 499 --------------PGDPGLMGERGEDG----PAGNGTEGFPGFPGYPGNRGAPGINGTK 540
                         PG PGL G +G+ G    P   GTEG  G  G PG  G PGI G +
Sbjct: 555 LLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQ 614

Query: 541 GYPGLKGDEGEAGDPGDDNND-----------------------IAPRGVKGAKGYRGPE 577
           G  G +G +GE G  GD  +                          P G++G+ G  GP 
Sbjct: 615 GSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPP 674

Query: 578 GPQGPPGHQGPPGPD 592
           GPQGP G  G PG +
Sbjct: 675 GPQGPSGLPGIPGEE 689



 Score =  279 bits (713), Expect = 1e-74
 Identities = 158/367 (43%), Positives = 185/367 (50%), Gaps = 43/367 (11%)

Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGR--PGDLGPVGYQGMKGEKGSRGEKGSR 313
           RG PGL G  G +G+RG PG+PG  G  GDPG    G  GP G  G KG  GSRG  G  
Sbjct: 474 RGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFP 533

Query: 314 GPKGYKGEKGKR------------------------GIDGVDGVKGEMGYPGLPGCKGSP 349
           GP+G  G  G                          G+ G+ G KG+ G PG PG +G+ 
Sbjct: 534 GPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTE 593

Query: 350 GFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEG---QPGEPGPPGEK 406
           G  G  GPPG  G PG  G +G +GE GADGE G+ G  G  G  G    PG PGPPG  
Sbjct: 594 GKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGAD 653

Query: 407 GEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDP 466
           G AG  G PG  G+PG+ G PG +GP G PG  G  G  G  G  G  G  G  G PG P
Sbjct: 654 GIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLP 713

Query: 467 GEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFP 525
           G  G  GP G++G  G  G+ G RG  G  G PG  GL G+ G+ GP G  G +G  G P
Sbjct: 714 GPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPP 773

Query: 526 GYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGH 585
           G  G+ G+PG  G  G PG KG +GE G PG               G+ GP GP G PG 
Sbjct: 774 GKNGSPGSPGEPGPSGTPGQKGSKGENGSPG-------------LPGFLGPRGPPGEPGE 820

Query: 586 QGPPGPD 592
           +G PG +
Sbjct: 821 KGVPGKE 827



 Score =  277 bits (708), Expect = 4e-74
 Identities = 168/403 (41%), Positives = 192/403 (47%), Gaps = 78/403 (19%)

Query: 255  ARGPPGLRGDPGFEGE---RGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG 311
            A GPPG++G PG EG    +G  GLPG  GE G  GR G  GP G  G  GE G  G +G
Sbjct: 658  AAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEG 717

Query: 312  SRGPKGYKGEKGKRGIDGVDGVKGEMGYPG---LPGCKGSPGFDGIQGPPGPKGDPGAFG 368
            +RGP G+KG  G  G  G  G  G MG PG   LPG  G  G  G QGP GP+G PG  G
Sbjct: 718  ARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNG 777

Query: 369  LKGEKGEPGADGEAGRPGSSGPSGDEGQPG------EPGPPGEKGEAGDEGNPGPDGAPG 422
              G  GEPG  G  G+ GS G +G  G PG       PG PGEKG  G EG PG  G PG
Sbjct: 778  SPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPG 837

Query: 423  ---ERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY-- 477
               ERG PG +G +G PG +G  GDPG  G +G  G  GP G+PG+ G  GP GP G   
Sbjct: 838  FKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPG 897

Query: 478  ---------------------------------------------RGDEGPPGSEGARGA 492
                                                         +G  GPPG  G  G 
Sbjct: 898  FPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGL 957

Query: 493  PGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGD 548
            PG AGP G+PG  G+ G +GP+G     G  G  G PG PG     G+ G  G PG+ G 
Sbjct: 958  PGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG----VGLRGEMGPPGIPGQ 1013

Query: 549  EGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
             GE G   D        G+ G  G +G  GP G PG  GPPGP
Sbjct: 1014 PGEPGYAKD--------GLPGIPGPQGETGPAGHPGLPGPPGP 1048



 Score =  276 bits (705), Expect = 9e-74
 Identities = 164/417 (39%), Positives = 195/417 (46%), Gaps = 87/417 (20%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP---------------VGYQGMK 301
            GPPG+ G  G +GERG  G  G+KG+ G PG PG +GP                G  G++
Sbjct: 606  GPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQ 665

Query: 302  GEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361
            G  G  G  G +GP G  G  G+ G +G DG  G  G PG  G  G PG +G +GPPG K
Sbjct: 666  GSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFK 725

Query: 362  GDPGAFGLKGEKGE------PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP 415
            G  G  G  G +GE      PG +G  G+ G +GP+G +G  G  GPPG+ G  G  G P
Sbjct: 726  GHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEP 785

Query: 416  GPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475
            GP G PG++G  GE G  G PG  GPRG PGE G +G  G+EG  G PG+PG  G  G  
Sbjct: 786  GPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDP 845

Query: 476  GYRGDEGPPGSEGARGAPG------------------------PAGPPGDPGLMGERGED 511
            G +GD+GPPG +G  G PG                        P GPPG PG  G RGE 
Sbjct: 846  GIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGES 905

Query: 512  -----------------------------GPA-GNGTEGFPGFPGYPGNRGAPGINGTKG 541
                                          PA    ++G PG PG PG  G PG  G  G
Sbjct: 906  PSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMG 965

Query: 542  YPGLKGDEGEAGDPGDDNNDIAPRGVKGAK--------GYRGPEGPQGPPGHQGPPG 590
             PG  G  G  G  G     I P+G +GAK        G RG  GP G PG  G PG
Sbjct: 966  EPGRPGQGGLEGPSG----PIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPG 1018



 Score =  272 bits (696), Expect = 1e-72
 Identities = 174/453 (38%), Positives = 206/453 (45%), Gaps = 114/453 (25%)

Query: 251 ECQPARGPPGLRGD----------PGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGM 300
           E  PA GPPGL G           PG +G +G+ G PG  GE G  GRPG+LGP G  G 
Sbjct: 323 EAGPA-GPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGP 381

Query: 301 KGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGC---------KGSPGF 351
            G KG  G  G+ G  G  G  G  G  G  G  G +G PGL G          KG+ G 
Sbjct: 382 PGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGE 441

Query: 352 DGIQGPPGPKGDPGAFGL-----KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEK 406
           +G  GP GP+GDPGA GL     KG+ GEPG  G  G PG  G  GD G PG PG PG +
Sbjct: 442 EGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSR 501

Query: 407 GEAGD--EGNPGPDGAPGERGGPGERGPRGTPGTRGPRG--------------------- 443
           G+ G    G PGP G PG++G PG RG  G PG +GP G                     
Sbjct: 502 GDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVC 561

Query: 444 ------------------------DPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRG 479
                                    PG  G +G +G  GP G+PG PG AGP G +G RG
Sbjct: 562 NDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERG 621

Query: 480 DEGPPGSEGARGAPG------PAGPP------------GDPGLMGERGEDGPAG------ 515
            +G  G +G +G PG      P G P            G PG+ G  G++GP G      
Sbjct: 622 ADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSG 681

Query: 516 ----------NGTEGFPGFPGYPGNRGAPGI---NGTKGYPGLKGDEGEAGDPGDDNNDI 562
                      G +G PG PG PG  G PG+    G +G PG KG  G++G PG      
Sbjct: 682 LPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESG 741

Query: 563 A-----PRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           A       G+ G  G  GP GPQGP G +GPPG
Sbjct: 742 AMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPG 774



 Score =  237 bits (604), Expect = 5e-62
 Identities = 144/331 (43%), Positives = 165/331 (49%), Gaps = 19/331 (5%)

Query: 296 GYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQ 355
           G + + GE G RGE G  G  G +GE G++G+ G  G KGE G PG PG    PG  G +
Sbjct: 244 GLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGF---PGVRGEK 300

Query: 356 GPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSG----DEGQPGEPGPPGEKGEAGD 411
           G  G KG+ G  GLKG++GE G  G AG PG  G +         PGE GP GEKG+ G 
Sbjct: 301 GDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGL 360

Query: 412 EGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEA---GPQGDQGREGPVGVPGDPGE 468
            G PG  G PGE G  G  GP G  G  G  G PG A   G  G  G  GP G PG  G 
Sbjct: 361 PGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGA 420

Query: 469 AGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYP 528
            G  G  G  G+ G  G+ G  G+PGP GP GDP   G  G  GP G G +G PG  G P
Sbjct: 421 PGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDP---GAPGLPGPPGKGKDGEPGLRGSP 477

Query: 529 GNRGAPGINGTKGYPGLKGDEGEAGDPG-DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQG 587
           G  G  G  G +G PG+ G  G  GDPG        P G  G KG  G  G  G PG QG
Sbjct: 478 GLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQG 537

Query: 588 PPGPDECEIL----DI-IMKMCSCCECKCGP 613
           P G D    L    DI ++    C +C  GP
Sbjct: 538 PAGRDGLSSLLSPGDINLLAKDVCNDCPPGP 568



 Score =  218 bits (556), Expect = 2e-56
 Identities = 131/334 (39%), Positives = 158/334 (47%), Gaps = 56/334 (16%)

Query: 255  ARGPPGLRGDPGFEGE---------RGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKG 305
            A G PG  G PG +G+         +G  G PG+ G  G PG PG  G  G +G KGE G
Sbjct: 742  AMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENG 801

Query: 306  SRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPG 365
            S G  G  GP+G  GE G++G+ G +GV G+ G PG  G +G PG  G +GPPG KG PG
Sbjct: 802  SPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPG 861

Query: 366  AFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEA---------------- 409
              G+ G KG  G  G  G PG +GP G  G PG+PG PG +GE+                
Sbjct: 862  DPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGK 921

Query: 410  -------------------GDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGP 450
                                 +G PGP G PG+ G PG  GP G PG  G  G  G +GP
Sbjct: 922  QLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGP 981

Query: 451  QGDQGREGPVGVPGDPG-----EAGPIGPKGYRGD-----EGPPGSEGARGAPGPAGPPG 500
             G +G  G  G PG PG     E GP G  G  G+     +G PG  G +G  GPAG PG
Sbjct: 982  IGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPG 1041

Query: 501  DPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAP 534
             PG  G  G+  P  +    F      PGN   P
Sbjct: 1042 LPGPPGPPGQCDP--SQCAYFASLAARPGNVKGP 1073



 Score =  210 bits (535), Expect = 5e-54
 Identities = 130/320 (40%), Positives = 156/320 (48%), Gaps = 42/320 (13%)

Query: 299 GMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPP 358
           G +G    R +  +      K   G + ++G  G +GE G PG PG +G  G  G+ G P
Sbjct: 220 GTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRP 279

Query: 359 GPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPD 418
           G            EKGE G  G  G PG  G  GD+G+ GE G PG KG+ G++G  GP 
Sbjct: 280 G------------EKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPA 327

Query: 419 G----------------APGERGGPGERGPRGTPGTRGPRGDPGEAGPQGD------QGR 456
           G                 PGE+G  GE+G  G PG  G +G PGE GPQG       +G+
Sbjct: 328 GPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQ 387

Query: 457 EGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGA---RGAPGPAGPPGDPGLMGERGEDGP 513
           EG  G PG  G  G  G  G  G  GPPGS GA   RG PG  G  G+ G  GE G  GP
Sbjct: 388 EGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGP 447

Query: 514 AG-NGTEGFPGFPGYP--GNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGA 570
            G  G  G PG PG P  G  G PG+ G+ G PG  G +G+ G PG   +    RG  G 
Sbjct: 448 VGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSP-GSRGDPGI 506

Query: 571 KGYRGPEGPQGPPGHQGPPG 590
            G  GP GP GPPG +G PG
Sbjct: 507 -GVAGPPGPSGPPGDKGSPG 525


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score =  300 bits (769), Expect = 4e-81
 Identities = 161/349 (46%), Positives = 192/349 (55%), Gaps = 20/349 (5%)

Query: 251  ECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310
            +C P  GPPGL G PGF+G++G PG PG +G  G  G  G  G  G  G+ G +GS+GE+
Sbjct: 1116 DCPP--GPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGER 1173

Query: 311  GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370
            G+ G  G KG++G  G+ G  G  G  G PG  G  G+ G  GIQG PG +G PG  G  
Sbjct: 1174 GADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPS 1233

Query: 371  GEKGEPGADGEAGRPGSSGPSGDEGQPGEPG---------PPGEKGEAGDEGNPGPDGAP 421
            G  G PG +G+ GR G  GP G+ G+ GEPG         PPG KG  GD G PGP G  
Sbjct: 1234 GLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGES 1293

Query: 422  GERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE 481
            G  G PG+ G  G  G  GP G  G  GP+G  G+ G    PG PGE GP G  G +G +
Sbjct: 1294 GAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGS---PGSPGEPGPSGTPGQKGSK 1350

Query: 482  GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKG 541
            G  GS G  G  GP GPPG+PG  G  G++G  G      PG PG+ G RG PGI G KG
Sbjct: 1351 GENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGK-----PGEPGFKGERGDPGIKGDKG 1405

Query: 542  YPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
             PG KG  G+ G PG   +     G +G  G  GP GP GPPG  G PG
Sbjct: 1406 PPGGKGQPGDPGIPGHKGH-TGLMGPQGLPGENGPVGPPGPPGQPGFPG 1453



 Score =  291 bits (745), Expect = 2e-78
 Identities = 165/391 (42%), Positives = 200/391 (51%), Gaps = 62/391 (15%)

Query: 256  RGPPGLRGDPGFEGERGK------PGLPGEKGEAGDPG-----RPGDL------------ 292
            +G PG RG PGF G +G       PG PGE+G  G PG      PGD+            
Sbjct: 1059 KGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCP 1118

Query: 293  -GPVGYQGM---KGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGC--- 345
             GP G  G+   KG+KG  G+ G  G +G KGE G  G+ G  G+ G  G  G  G    
Sbjct: 1119 PGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGE 1178

Query: 346  ------KGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE 399
                  +G PG  G  GPPG  G PGA G+ G  G PG  G    PG  GP G +G  G 
Sbjct: 1179 VGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGS---PGKEGPPGPQGPSGL 1235

Query: 400  PGPPGEKGEAGDEGNPGPDGAPGERGGPGERGP---RGTPGTRGPRGDPGEAGPQGDQGR 456
            PG PGE+G+ G +G PGP G PG+ G PG  GP   RG PG +G  GD G  GP+G+ G 
Sbjct: 1236 PGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGA 1295

Query: 457  ---EGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDG- 512
                G  G+PG  G+ GP GP+G +G  GPPG  G+ G+PG  GP G PG  G +GE+G 
Sbjct: 1296 MGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGS 1355

Query: 513  ------------PAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNN 560
                        P   G +G PG  G PG  G PG  G +G PG+KGD+G  G  G   +
Sbjct: 1356 PGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGD 1415

Query: 561  DIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
                 G+ G KG+ G  GPQG PG  GP GP
Sbjct: 1416 P----GIPGHKGHTGLMGPQGLPGENGPVGP 1442



 Score =  282 bits (722), Expect = 1e-75
 Identities = 163/357 (45%), Positives = 189/357 (52%), Gaps = 24/357 (6%)

Query: 257 GPPGLRGD----PGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312
           GPPG+ G      G +GE+G PG  G +G  G PG  G +GP G  G  G +G RG+KG 
Sbjct: 641 GPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGD 700

Query: 313 RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK-- 370
            GP G  G  G +G  G  GV G  G  G PG  G  GF G  GPPGP G PG  G    
Sbjct: 701 MGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGP 760

Query: 371 ----GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGG 426
               G KGEPG  GE G PG  G  G+ G+ G  G PGEKGEAG  G PG  G  GE+G 
Sbjct: 761 PGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGD 820

Query: 427 PGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGV----PGDPGEAGPIGPKGYRGDEG 482
            GE+G  G PG +G RG+ GEAGP G  G  G   +    P  PGE GP G KG  G  G
Sbjct: 821 QGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPG 880

Query: 483 PPGSEGARGAPGPAGPPGDPGLMGERGEDG-------PAGNGTEGFPGFPGYPGNRGAPG 535
            PG +G  G  GP GP G PG  G+ G  G       P   G  G PG  G PG+ GAPG
Sbjct: 881 EPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPG 940

Query: 536 INGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGP--EGPQGPPGHQGPPG 590
           + GT G  G +G++G AG+ G     + PRG  GA G  GP  +G  G PG +G PG
Sbjct: 941 LRGTPGKDGERGEKGAAGEEGSP-GPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPG 996



 Score =  280 bits (715), Expect = 6e-75
 Identities = 165/377 (43%), Positives = 189/377 (50%), Gaps = 44/377 (11%)

Query: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDL------GPVGYQGMKGEKGS 306
           Q  +G  G  G PG  G  G  G+ GE GE G+PG PG++      GP G  G  G  G+
Sbjct: 526 QGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGA 585

Query: 307 RGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366
            G +G RG KG +GEKG+RG+DG  G  G+ G  G PG  G  G  G +G  GP G PG 
Sbjct: 586 PGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGV 645

Query: 367 -------FGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDG 419
                   GLKGE+G PG  G  G PG  G  G  G  G  GPPG +G  G +G+ GP G
Sbjct: 646 PGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPG 705

Query: 420 APGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRG 479
            PG  G  G  GP G PG  GP G PG  G  G  G+ GP G  G PG+ GP GP     
Sbjct: 706 IPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGP----- 760

Query: 480 DEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFPGYPGNRGAPG 535
             GPPG++G  G  G  G PG PGL GE GE G AG     G  G PG PG+PG RG  G
Sbjct: 761 -PGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKG 819

Query: 536 INGTK---GYPGLKGDEGEAGDPGDDN------------------NDIAPRGVKGAKGYR 574
             G K   G PGLKGD GE G+ G                      +  P+G KG  G  
Sbjct: 820 DQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLP 879

Query: 575 GPEGPQGPPGHQGPPGP 591
           G  G QG PG  GP GP
Sbjct: 880 GEPGLQGRPGELGPQGP 896



 Score =  277 bits (708), Expect = 4e-74
 Identities = 168/403 (41%), Positives = 192/403 (47%), Gaps = 78/403 (19%)

Query: 255  ARGPPGLRGDPGFEGE---RGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG 311
            A GPPG++G PG EG    +G  GLPG  GE G  GR G  GP G  G  GE G  G +G
Sbjct: 1211 AAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEG 1270

Query: 312  SRGPKGYKGEKGKRGIDGVDGVKGEMGYPG---LPGCKGSPGFDGIQGPPGPKGDPGAFG 368
            +RGP G+KG  G  G  G  G  G MG PG   LPG  G  G  G QGP GP+G PG  G
Sbjct: 1271 ARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNG 1330

Query: 369  LKGEKGEPGADGEAGRPGSSGPSGDEGQPG------EPGPPGEKGEAGDEGNPGPDGAPG 422
              G  GEPG  G  G+ GS G +G  G PG       PG PGEKG  G EG PG  G PG
Sbjct: 1331 SPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPG 1390

Query: 423  ---ERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY-- 477
               ERG PG +G +G PG +G  GDPG  G +G  G  GP G+PG+ G  GP GP G   
Sbjct: 1391 FKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPG 1450

Query: 478  ---------------------------------------------RGDEGPPGSEGARGA 492
                                                         +G  GPPG  G  G 
Sbjct: 1451 FPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGL 1510

Query: 493  PGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGD 548
            PG AGP G+PG  G+ G +GP+G     G  G  G PG PG     G+ G  G PG+ G 
Sbjct: 1511 PGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG----VGLRGEMGPPGIPGQ 1566

Query: 549  EGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
             GE G   D        G+ G  G +G  GP G PG  GPPGP
Sbjct: 1567 PGEPGYAKD--------GLPGIPGPQGETGPAGHPGLPGPPGP 1601



 Score =  276 bits (705), Expect = 9e-74
 Identities = 164/417 (39%), Positives = 195/417 (46%), Gaps = 87/417 (20%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGP---------------VGYQGMK 301
            GPPG+ G  G +GERG  G  G+KG+ G PG PG +GP                G  G++
Sbjct: 1159 GPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQ 1218

Query: 302  GEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361
            G  G  G  G +GP G  G  G+ G +G DG  G  G PG  G  G PG +G +GPPG K
Sbjct: 1219 GSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFK 1278

Query: 362  GDPGAFGLKGEKGE------PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP 415
            G  G  G  G +GE      PG +G  G+ G +GP+G +G  G  GPPG+ G  G  G P
Sbjct: 1279 GHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEP 1338

Query: 416  GPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475
            GP G PG++G  GE G  G PG  GPRG PGE G +G  G+EG  G PG+PG  G  G  
Sbjct: 1339 GPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDP 1398

Query: 476  GYRGDEGPPGSEGARGAPG------------------------PAGPPGDPGLMGERGED 511
            G +GD+GPPG +G  G PG                        P GPPG PG  G RGE 
Sbjct: 1399 GIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGES 1458

Query: 512  -----------------------------GPA-GNGTEGFPGFPGYPGNRGAPGINGTKG 541
                                          PA    ++G PG PG PG  G PG  G  G
Sbjct: 1459 PSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMG 1518

Query: 542  YPGLKGDEGEAGDPGDDNNDIAPRGVKGAK--------GYRGPEGPQGPPGHQGPPG 590
             PG  G  G  G  G     I P+G +GAK        G RG  GP G PG  G PG
Sbjct: 1519 EPGRPGQGGLEGPSG----PIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPG 1571



 Score =  273 bits (698), Expect = 6e-73
 Identities = 185/481 (38%), Positives = 214/481 (44%), Gaps = 145/481 (30%)

Query: 257  GPPGLRGDPGFEGERG---KPGLPGEKGEAGDPGRPGDLGPVG------YQGMKGEKGSR 307
            GPPG +G+PG  GE G   KPGL GE GE G  GRPG+ G  G      + G++GEKG +
Sbjct: 762  GPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQ 821

Query: 308  GEKGSRGPKGYKGEKGKRG----------------------IDGVDGVKGEMGYPGLPG- 344
            GEKG  G  G KG++G++G                      + G  G KGE G PGLPG 
Sbjct: 822  GEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGE 881

Query: 345  --CKGSPGFDGIQGPPGP---KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE 399
               +G PG  G QGP GP   KG  GA G  G  G PGA G  G PG SGP G  G PG 
Sbjct: 882  PGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGL 941

Query: 400  PGPPG------EKGEAGDEGNPGP--------------------DGAPGERGGPGERGPR 433
             G PG      EKG AG+EG+PGP                    DG PG RG PG  GP 
Sbjct: 942  RGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPL 1001

Query: 434  GT-----------------------------PGTRGPRGDPG--EAGPQGDQGREGPVGV 462
            GT                             PG+ G RGDPG   AGP G  G  G  G 
Sbjct: 1002 GTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGS 1061

Query: 463  PGDPGEAGPIGPKGYRGDEGPPGSEGARGAPG------------------------PAGP 498
            PG  G  G  GP+G  G +G PG+ G RG PG                        P GP
Sbjct: 1062 PGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGP 1121

Query: 499  PGDPGLMGERGEDG----PAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGD 554
            PG PGL G +G+ G    P   GTEG  G  G PG  G PGI G +G  G +G +GE G 
Sbjct: 1122 PGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQ 1181

Query: 555  PGDDNND-----------------------IAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
             GD  +                          P G++G+ G  GP GPQGP G  G PG 
Sbjct: 1182 KGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGE 1241

Query: 592  D 592
            +
Sbjct: 1242 E 1242



 Score =  272 bits (696), Expect = 1e-72
 Identities = 163/375 (43%), Positives = 187/375 (49%), Gaps = 53/375 (14%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGE-----------------------KGEAGDPGRPGD-- 291
            GPPG +G  G  G RG PGLPG                        KG+ G PG PG   
Sbjct: 979  GPPG-KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPG 1037

Query: 292  ------LGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGC 345
                  +G  G  G  G  G +G  GSRG  G+ G +G  G DG  G  GE G PG PG 
Sbjct: 1038 SRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGL 1097

Query: 346  KG--SPGFDGIQG-------PPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQ 396
                SPG   +         PPGP G PG  G KG+KG P   G+ GR G+ G  G+ G 
Sbjct: 1098 SSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVP---GKPGREGTEGKKGEAGP 1154

Query: 397  PGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGR 456
            PG PGPP   G AG +G+ G  GA GE G  G++G  G PG  GP G+PG  G  G  G 
Sbjct: 1155 PGLPGPP---GIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGA 1211

Query: 457  EGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN 516
             GP G+ G PG+ GP GP+G  G  G PG EG  G  G  GPPG+PG  GE G  GP   
Sbjct: 1212 AGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGP--E 1269

Query: 517  GTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGP 576
            G  G PGF G+ G+ GAPG  G  G  GL G EG  G  G    D  P G +G +G RGP
Sbjct: 1270 GARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDG----DTGPTGPQGPQGPRGP 1325

Query: 577  EGPQGPPGHQGPPGP 591
             G  G PG  G PGP
Sbjct: 1326 PGKNGSPGSPGEPGP 1340



 Score =  271 bits (693), Expect = 2e-72
 Identities = 156/378 (41%), Positives = 184/378 (48%), Gaps = 46/378 (12%)

Query: 248  CSFECQPARGPPGLRGDPGFEGERGKPGL-----PGEKGEAGDPGRPGDLGPVGY---QG 299
            C+   Q  +G  G  G PG  G RG PG+     PG  G  GD G PG  G  G+   QG
Sbjct: 1016 CALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQG 1075

Query: 300  MKGEKGSRGEKGSRGPKGYKG---------------------EKGKRGIDGVDGVKGEMG 338
              G  G+ G  G RGP G  G                       G  G+ G+ G KG+ G
Sbjct: 1076 PAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKG 1135

Query: 339  YPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEG--- 395
             PG PG +G+ G  G  GPPG  G PG  G +G +GE GADGE G+ G  G  G  G   
Sbjct: 1136 VPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMG 1195

Query: 396  QPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQG 455
             PG PGPPG  G AG  G PG  G+PG+ G PG +GP G PG  G  G  G  G  G  G
Sbjct: 1196 PPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPG 1255

Query: 456  REGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG 515
              G  G PG PG  G  GP G++G  G  G+ G RG  G  G PG  GL G+ G+ GP G
Sbjct: 1256 EPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTG 1315

Query: 516  -NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYR 574
              G +G  G PG  G+ G+PG  G  G PG KG +GE G PG               G+ 
Sbjct: 1316 PQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPG-------------LPGFL 1362

Query: 575  GPEGPQGPPGHQGPPGPD 592
            GP GP G PG +G PG +
Sbjct: 1363 GPRGPPGEPGEKGVPGKE 1380



 Score =  270 bits (691), Expect = 4e-72
 Identities = 172/419 (41%), Positives = 203/419 (48%), Gaps = 82/419 (19%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            GPPG  G PG  GE G PG PG  G  G PG+ G  GP G  G KGE G RGE G  G  
Sbjct: 723  GPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKP 782

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376
            G +GE G++G+ G  G KGE G PG      +PGF G++G  G +G+      KGE G P
Sbjct: 783  GLRGEIGEQGLAGRPGEKGEAGLPG------APGFPGVRGEKGDQGE------KGELGLP 830

Query: 377  GADGEAGRPGSSGPSGDEGQPG-------EPGPPGEKGEAGDEGNPGPDGAPGERGGPGE 429
            G  G+ G  G +GP+G  G PG        P  PGE+G  G++G+PG  G PG +G PGE
Sbjct: 831  GLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGE 890

Query: 430  RGPR---------------GTPGTRGPRGDPGEAGPQGDQGREGPVGVP---GDPGEAGP 471
             GP+               G PG  G  G PG  G  G  G  G VG P   G PG+ G 
Sbjct: 891  LGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGE 950

Query: 472  IGPKGYRGDEGPPGSEGAR---GAPGPAGPP-----GDPGLMGERGEDGPAG-------- 515
             G KG  G+EG PG  G R   GAPG  GPP     G+PGL G  G  GP G        
Sbjct: 951  RGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKV 1010

Query: 516  -------------NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDI 562
                          G  G PG PG PG+RG PGI G  G PG  G  G+ G PG      
Sbjct: 1011 RGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSGPPGDKGSPGS----- 1064

Query: 563  APRGVKGAKGYRGP---EGPQGPPGHQGPPGPDECEIL----DI-IMKMCSCCECKCGP 613
              RG+ G  G +GP   +G  G PG +GPPG      L    DI ++    C +C  GP
Sbjct: 1065 --RGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGP 1121



 Score =  262 bits (669), Expect = 1e-69
 Identities = 167/405 (41%), Positives = 199/405 (49%), Gaps = 85/405 (20%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAG------DPGRPGDLGPVGYQGMKGEKGSRGEK 310
            G PGLRG PG +GERG+ G  GE+G  G      DPG PG  GP G +G  GE G RG  
Sbjct: 937  GAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSP 995

Query: 311  GSRGPKGYKGEKGK-RGIDG-------VDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKG 362
            G  GP G K   GK RG +        V G +G  G PG PG +G PG  G+ GPPGP G
Sbjct: 996  GLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSG 1054

Query: 363  DPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPG---PPGEKGE----------- 408
             PG      +KG PG+ G  G PG  GP+G +G PG PG   PPG+ G            
Sbjct: 1055 PPG------DKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINL 1108

Query: 409  -AGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPG 467
             A D  N  P G PG  G PG +G +G PG       PG  G +G +G  GP G+PG PG
Sbjct: 1109 LAKDVCNDCPPGPPGLPGLPGFKGDKGVPGK------PGREGTEGKKGEAGPPGLPGPPG 1162

Query: 468  EAGPIGPKGYRGDEGPPGSEGARGAPG------PAGPP------------GDPGLMGERG 509
             AGP G +G RG +G  G +G +G PG      P G P            G PG+ G  G
Sbjct: 1163 IAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPG 1222

Query: 510  EDGPAG----------------NGTEGFPGFPGYPGNRGAPGI---NGTKGYPGLKGDEG 550
            ++GP G                 G +G PG PG PG  G PG+    G +G PG KG  G
Sbjct: 1223 KEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTG 1282

Query: 551  EAGDPGDDNNDIA-----PRGVKGAKGYRGPEGPQGPPGHQGPPG 590
            ++G PG      A       G+ G  G  GP GPQGP G +GPPG
Sbjct: 1283 DSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPG 1327



 Score =  228 bits (582), Expect = 2e-59
 Identities = 136/309 (44%), Positives = 159/309 (51%), Gaps = 50/309 (16%)

Query: 332 GVKGEMGYPG---LPGCKGSPGFDGIQGPPGPKGDPGAFGL-------KGEKGEPGADGE 381
           G KGEMG  G   LPG KG  G  G  G PGPKG+ G  G+       KGEKG  G  G 
Sbjct: 481 GEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGP 540

Query: 382 AGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGP 441
            GR GS G  G+ G+ GEPG PGE G  G +G PG  G PG  G PG +G RG  GTRG 
Sbjct: 541 PGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGE 600

Query: 442 RGD------PGEAGPQGDQGREGPVGVPGDPGEAGPIGP-------------KGYRGDEG 482
           +G+      PG+ G  G QGR GP GV G  GE G +GP             +G +G++G
Sbjct: 601 KGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQG 660

Query: 483 PPGSEGARGAPGPA------------GPPGDPGLMGERGEDGPAG-------NGTEGFPG 523
            PG  G +GAPGP             GPPG  GL G++G+ GP G        G  G PG
Sbjct: 661 APGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPG 720

Query: 524 FPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDD--NNDIAPRGVKGAKGYRGPEGPQG 581
            PG PG  G+PG+ G  G+PG  G  G  G PG D  N    P G KG  G RG +G  G
Sbjct: 721 VPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPG 780

Query: 582 PPGHQGPPG 590
            PG +G  G
Sbjct: 781 KPGLRGEIG 789



 Score =  218 bits (556), Expect = 2e-56
 Identities = 131/334 (39%), Positives = 158/334 (47%), Gaps = 56/334 (16%)

Query: 255  ARGPPGLRGDPGFEGE---------RGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKG 305
            A G PG  G PG +G+         +G  G PG+ G  G PG PG  G  G +G KGE G
Sbjct: 1295 AMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENG 1354

Query: 306  SRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPG 365
            S G  G  GP+G  GE G++G+ G +GV G+ G PG  G +G PG  G +GPPG KG PG
Sbjct: 1355 SPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPG 1414

Query: 366  AFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEA---------------- 409
              G+ G KG  G  G  G PG +GP G  G PG+PG PG +GE+                
Sbjct: 1415 DPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGK 1474

Query: 410  -------------------GDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGP 450
                                 +G PGP G PG+ G PG  GP G PG  G  G  G +GP
Sbjct: 1475 QLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGP 1534

Query: 451  QGDQGREGPVGVPGDPG-----EAGPIGPKGYRGD-----EGPPGSEGARGAPGPAGPPG 500
             G +G  G  G PG PG     E GP G  G  G+     +G PG  G +G  GPAG PG
Sbjct: 1535 IGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPG 1594

Query: 501  DPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAP 534
             PG  G  G+  P  +    F      PGN   P
Sbjct: 1595 LPGPPGPPGQCDP--SQCAYFASLAARPGNVKGP 1626



 Score =  170 bits (431), Expect = 6e-42
 Identities = 99/214 (46%), Positives = 119/214 (55%), Gaps = 16/214 (7%)

Query: 388 SGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERG--PRGTPGTRGPRGDP 445
           S P+G++G+ G  GP G  G  GD G  GP GAPG +G  G+ G  P G  G +G +G  
Sbjct: 477 SCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQ-GEKGEKGSL 535

Query: 446 GEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLM 505
           G  GP G  G +G  G PG+ GE G  G  G RG +GPPG       PGP G  G PGL 
Sbjct: 536 GLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPG------LPGPPGRVGAPGLQ 589

Query: 506 GERGEDGPAGN----GTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNND 561
           GERGE G  G     G +GFPG PG  G +G PG +G  G  G KGD G AG PG   + 
Sbjct: 590 GERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSV 649

Query: 562 IAPRGVKGAKGYRGPEGPQG---PPGHQGPPGPD 592
           +   G+KG +G  GP G QG   PPG +GP GP+
Sbjct: 650 VQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPE 683



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 45/157 (28%), Positives = 77/157 (49%), Gaps = 20/157 (12%)

Query: 609 CKCGPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHS 668
           CK    DL+F+LD+S S+G ++FE  + +V  ++D        +  P ++  GVV+YS  
Sbjct: 32  CKSVHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTF------EVGPDRTRVGVVRYSD- 84

Query: 669 QMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNR------ 722
             +   +       + +E+K A + L +  G T TG+AL+Y   +   P    R      
Sbjct: 85  --RPTTAFELGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAY 142

Query: 723 --IALVITDGRS-DTQRDTTPLNVLCSPGIQVVSVGI 756
             +A+++TDGRS D   D          GI++ +VG+
Sbjct: 143 KQVAILLTDGRSQDLVLDAAA--AAHRAGIRIFAVGV 177



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 60/207 (28%), Positives = 92/207 (44%), Gaps = 33/207 (15%)

Query: 829  DITILLDGSASVGSHNFDTTKRFAKRLAERF-LTAGRTDPAHDVRVAVVQYSGTGQQRPE 887
            D+  LLD S+SVG  +F+  +++   L + F +   RT      RV VV+YS     RP 
Sbjct: 38   DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRT------RVGVVRYS----DRPT 87

Query: 888  RA-SLQFLQNYTALASAVDAMDFINDATDVNDALGYVT-RFYREASSG-----AAKKRLL 940
             A  L    +   + +A   + +    T+  DAL Y+T R +   + G     A K+  +
Sbjct: 88   TAFELGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAI 147

Query: 941  LFSDGNSQGATPAAIEKAVQEAQRAGIEIFVVVVGRQVNEPHIRVLVTGKTAEYDVAYGE 1000
            L +DG SQ      +  A   A RAGI IF V VG  + E    +    K+A        
Sbjct: 148  LLTDGRSQD----LVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSA-------- 195

Query: 1001 SHLFRVPSYQAL--LRGVFHQTVSRKV 1025
             H+F V  + A+  +RG   + +   V
Sbjct: 196  -HVFHVSDFNAIDKIRGKLRRRLCENV 221



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 45/187 (24%), Positives = 78/187 (41%), Gaps = 26/187 (13%)

Query: 37  DLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLRDRYYRCDRNLVWNAGALHYSDE 96
           DL F+LDTS SV           +KV+ +    +D         DR  V   G + YSD 
Sbjct: 38  DLVFLLDTSSSVGKE------DFEKVRQWVANLVDTFE---VGPDRTRV---GVVRYSDR 85

Query: 97  VEIIQGLTRMPGGRDALKSSVDAVKYFGKGTYTDCAIKKGLEQLLV--GGSHLKENKY-- 152
                 L  + G ++ +K++   + Y G  T T  A++    +      G   ++  Y  
Sbjct: 86  PTTAFEL-GLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQ 144

Query: 153 -LIVVTDGHPLEGYKEPCGGLEDAVNEAKHLGVKVFSVAITPDHLEPRLSIIATDHTYRR 211
             I++TDG   +        + DA   A   G+++F+V +  + L+  L  IA++     
Sbjct: 145 VAILLTDGRSQD-------LVLDAAAAAHRAGIRIFAVGV-GEALKEELEEIASEPKSAH 196

Query: 212 NFTAADW 218
            F  +D+
Sbjct: 197 VFHVSDF 203


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score =  300 bits (767), Expect = 6e-81
 Identities = 164/371 (44%), Positives = 193/371 (52%), Gaps = 37/371 (9%)

Query: 257  GPPGLRGDPGF-----EGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG 311
            G  G+ GDP F      G+RG  G+PG KG  GDPG PG  GP G  G  G KG +G +G
Sbjct: 754  GQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREG 813

Query: 312  SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKG 371
              G  G  G  G     G  G+ G+ G PG PG  G+PG  G  G  GP G  G  GL G
Sbjct: 814  HAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPG 873

Query: 372  EKGEPGADGEAGRPGSSGPSGDEGQPGEPGP------PGEKGEAGDEGNPGPDGAPGERG 425
              G PGA G  G PG  GP GD+G PG PGP      PG  G  G+ G PG +G PG +G
Sbjct: 874  LPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKG 933

Query: 426  GPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY---RGDEG 482
             PGE+G  G PG RG RG  G  GP GD+G    +   G PGE GP G  G+   RGD+G
Sbjct: 934  EPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKG 993

Query: 483  PPGSEGARGAPGPAGPP----GDPGLMGERGEDGPAG----NGTEGFPGFPGYPGNRGAP 534
             PG +G RG PG  GPP    G+PG  G+ G  GP G     G  GF GFPG PG++G P
Sbjct: 994  TPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEP 1053

Query: 535  GINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVK---------------GAKGYRGPEGP 579
            G  G  G+ G+ G  G  G+ GD  +   P G K               G +G  G +GP
Sbjct: 1054 GSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGP 1113

Query: 580  QGPPGHQGPPG 590
            +G PG  GPPG
Sbjct: 1114 RGSPGRPGPPG 1124



 Score =  288 bits (738), Expect = 1e-77
 Identities = 181/436 (41%), Positives = 203/436 (46%), Gaps = 106/436 (24%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            G PG  GD GF GERG  G PG +G  G+PGR    GP G+   +GE G +G+ G  GP 
Sbjct: 975  GEPGPPGDDGFPGERGDKGTPGMQGRRGEPGR---YGPPGFH--RGEPGEKGQPGPPGPP 1029

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA-FGLKGEKGE 375
            G  G  G RG  G  G+ G+ G PG PG  G  G DG +GP G KGDP + FG  G KGE
Sbjct: 1030 GPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGE 1089

Query: 376  PG---------ADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGG 426
            PG         A GE G PG  GP G  G+PG PG  G  G  GD G PG  G PGE G 
Sbjct: 1090 PGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGD 1149

Query: 427  PGERG-----------------------------------------------PRGTPGTR 439
            PG RG                                               P G PG +
Sbjct: 1150 PGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLK 1209

Query: 440  GPRGDPGEAG--PQGDQGREGPVGVPGDPGEAGPIG-----PK-----GYRGDEGPPGSE 487
            G RGDPG  G  P G +G++GP G PG  G  GP G     PK     G  GD+GPPG +
Sbjct: 1210 GERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPD 1269

Query: 488  GARGAPGPAG-------------------------PPGDPGLMGERGEDGPAGN-GTEGF 521
            G RGAPGP G                         PPG PG  G  G DG  G  G  GF
Sbjct: 1270 GPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGF 1329

Query: 522  PG------FPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRG 575
            PG      FPG PG +G PG  G KG  GL G  GE G P D ++     G+ GA G RG
Sbjct: 1330 PGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRG 1389

Query: 576  PEGPQGPPGHQGPPGP 591
            PEG  G PG +GP GP
Sbjct: 1390 PEGAMGLPGMRGPSGP 1405



 Score =  285 bits (730), Expect = 1e-76
 Identities = 161/364 (44%), Positives = 188/364 (51%), Gaps = 37/364 (10%)

Query: 257  GPPGL---RGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSR 313
            GPPG    RG PG  G+ G PG PG  G  G  G+PGD+GP G  GMKG  G  G  G+ 
Sbjct: 822  GPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAH 881

Query: 314  GPKGYKGEKGKRGIDGVDGVKGEMG------YPGLPGCKGSPGFDGIQGPPGPKGDPGAF 367
            GP G  G  G  G DG+ G  G  G      +PG PG +G PG +G  G  G  G+ G  
Sbjct: 882  GPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMS 941

Query: 368  GLKGEKGEPGADGEAGRPGSSGPS---GDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGER 424
            GL G++G  GA G  G PG  G       +G PGEPGPPG+ G  G+ G+ G  G  G R
Sbjct: 942  GLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRR 1001

Query: 425  GGPGERGP----RGTPGTRGPRGDPGEAGPQGDQGREGPV---GVPGDPGEAGPIGPKGY 477
            G PG  GP    RG PG +G  G PG  GP G  G  G +   G+PGD GE G  GP G+
Sbjct: 1002 GEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGF 1061

Query: 478  RGDEGPPGSEGAR-------GAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFPG 526
             G +G  G +G +       G PGP G PG PG  G  G  G  G     G  G PG PG
Sbjct: 1062 SGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPG 1121

Query: 527  YPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQ 586
             PG+ G PG  G  G PGL+G  GE GDPG       PRG++G  G  GP G +GP G  
Sbjct: 1122 PPGSSGPPGCPGDHGMPGLRGQPGEMGDPG-------PRGLQGDPGIPGPPGIKGPSGSP 1174

Query: 587  GPPG 590
            G  G
Sbjct: 1175 GLNG 1178



 Score =  282 bits (722), Expect = 1e-75
 Identities = 168/381 (44%), Positives = 201/381 (52%), Gaps = 49/381 (12%)

Query: 256  RGPPGLRGDPGFEGERGKPGL---PGEKGEAGDPGRPGDLGPVGYQGMKG---------- 302
            +GP GL G PGF GERGKPG    PG KGE G+ G  G  G  G +G KG          
Sbjct: 905  KGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGE 964

Query: 303  -----EKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGC-KGSPGFDGIQG 356
                 +KG+ GE G  G  G+ GE+G +G  G+ G +GE G  G PG  +G PG  G  G
Sbjct: 965  MAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPG 1024

Query: 357  PPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSG---------DEGQPGEP----GPP 403
            PPGP G PG+ GL+G  G PG  G+ G PGS GP G          +G  G+P    GPP
Sbjct: 1025 PPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPP 1084

Query: 404  GEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVP 463
            G KGE G  G PG  GA GE+G PG +GPRG+PG  GP   PG +GP G  G  G  G+ 
Sbjct: 1085 GPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGP---PGSSGPPGCPGDHGMPGLR 1141

Query: 464  GDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG------NG 517
            G PGE G  GP+G +GD G PG  G +G  G  G  G  GL G++G  G +G       G
Sbjct: 1142 GQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPG 1201

Query: 518  TEGFPGFPGYPGNRGAPGIN--------GTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKG 569
              G PG  G  G+ G+PGI+        G  G PG  G  G AG  G    DI   G  G
Sbjct: 1202 PVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPG 1261

Query: 570  AKGYRGPEGPQGPPGHQGPPG 590
             +G  GP+GP+G PG  G PG
Sbjct: 1262 DQGPPGPDGPRGAPGPPGLPG 1282



 Score =  279 bits (713), Expect = 1e-74
 Identities = 172/421 (40%), Positives = 201/421 (47%), Gaps = 89/421 (21%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            +G PG  G PG  G +G PGLPG  G  G PG PG  GP G  G+ G  G +G +G  G 
Sbjct: 854  KGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGF 913

Query: 316  KGYKGEKGKRGIDGVDGVKGE---MGYPGLPGCKGSPGFDGIQGPPG------------- 359
             G+ GE+GK G +G  G KGE    G  GLPG +G  G  G  GPPG             
Sbjct: 914  PGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGT 973

Query: 360  -----PKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSG-------DEGQPGEPGPPGEKG 407
                 P GD G  G +G+KG PG  G  G PG  GP G       ++GQPG PGPPG  G
Sbjct: 974  PGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPG 1033

Query: 408  EAG------------DEGNPGPDGAPGERGGPGERGPRGTPGTR-------GPRGDPGE- 447
              G            D+G PG  G PG  G  G RGP+G  G         GP+G+PG  
Sbjct: 1034 STGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSP 1093

Query: 448  --------AGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPG---SEGARGAPGPA 496
                    +G QG  G +GP G PG PG  G  GP G  GD G PG     G  G PGP 
Sbjct: 1094 GCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPR 1153

Query: 497  GPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGIN-----GTKGYPGLKGDEG 550
            G  GDPG+ G  G  GP+G+ G  G  G  G  G +GA G++     G  G PGLKG+ G
Sbjct: 1154 GLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERG 1213

Query: 551  EAGDPGDDNNDIAPRGVKGAKGYRGPEGPQ-------------------GPPGHQGPPGP 591
            + G PG     I+P G +G KG  GP G                     GPPG QGPPGP
Sbjct: 1214 DPGSPG-----ISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGP 1268

Query: 592  D 592
            D
Sbjct: 1269 D 1269



 Score =  270 bits (690), Expect = 5e-72
 Identities = 174/406 (42%), Positives = 186/406 (45%), Gaps = 73/406 (17%)

Query: 252 CQPA-RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310
           C+P   GPPG  G PG +G +G  GLPG  G  GDPG PG  GP G  G  G  G  G K
Sbjct: 494 CEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNK 553

Query: 311 GSRGP---KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD---- 363
           G++G       KG KG+RG DG  G      +PG PG  G  G  G +G PGP GD    
Sbjct: 554 GAKGDMVVSRVKGHKGERGPDGPPG------FPGQPGSHGRDGHAGEKGDPGPPGDHEDA 607

Query: 364 -PGAFGLKGEKGEPGADGEAGRPGSS--GPSGDEGQPGEP-------------------- 400
            PG  G  G  G PG  G  G PG    GP G+ G PG P                    
Sbjct: 608 TPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTIS 667

Query: 401 ---------GPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQ 451
                    GPPG  G  G +G PGP GAPG  G  G +G  GTPGT    G PG  G  
Sbjct: 668 CNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDM 727

Query: 452 GDQGREG-----PVGVPGDPGEAGPIGPKGYRGDE-----GPPGSEGARGAPGPAGPPGD 501
           GD G  G     PVG PG PG  G  G KG  GD      GPPG  G  G PG  GP GD
Sbjct: 728 GDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGD 787

Query: 502 PGLMGERGEDGPAG-------NGTEGFPGFPGYPG------NRGAPGI---NGTKGYPGL 545
           PG  G  G  G  G        G EG  GFPG PG       RGAPGI    G  GYPG 
Sbjct: 788 PGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGS 847

Query: 546 KGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
            G  G  G PGD      P G+KG  G  G  G  GPPG  G PGP
Sbjct: 848 PGAPGGKGQPGDVGPP-GPAGMKGLPGLPGRPGAHGPPGLPGIPGP 892



 Score =  265 bits (678), Expect = 1e-70
 Identities = 166/399 (41%), Positives = 191/399 (47%), Gaps = 59/399 (14%)

Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG- 314
           RGPPG  GD G +G  G PG PG  G  G PG PG  G  G  G  G +G  G  G RG 
Sbjct: 97  RGPPGAAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGA 156

Query: 315 -----PKGYKGEKGKRG-----IDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDP 364
                P G+ GEKG++G     +  V G++G+ G PGLPG  GS G  G  GP G  G+P
Sbjct: 157 LGPGGPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEP 216

Query: 365 GAFGLKGEKGEPGADGE--AGRPGSSGPSGDEGQPGEPGPP------------GEKGEAG 410
           G  G  G+ G PG  G    G  G  G  G+ GQ G PGP             GEKG  G
Sbjct: 217 GLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKG 276

Query: 411 DEGNPGPDGAPGERG--GPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGE 468
             G  G  G PG +G  G G +G +G PG  GPRGDPG  G  G  G +G +G+ GDPG 
Sbjct: 277 IPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGL 336

Query: 469 AGPIGPKGYRGDEGPPGSEGARGAP-----GPAGPPGDPGLMGERGEDGPAGN------- 516
            G IGPKG  G+ G PG  G    P     GP G PG PG  GE G+ GP G        
Sbjct: 337 FGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRP 396

Query: 517 -----------GTEGFPGFPGYPGNRG-------APGINGTKGYPGLKGDEGEAGDPGDD 558
                      G +GFPG PG PG  G       APG  G  G PGL G  G  G PG  
Sbjct: 397 GEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSS 456

Query: 559 --NNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPDECE 595
                +   G +G KG  GP G +GP G +G  G   CE
Sbjct: 457 VIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACE 495



 Score =  262 bits (669), Expect = 1e-69
 Identities = 168/391 (42%), Positives = 191/391 (48%), Gaps = 64/391 (16%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGE--AGDPGRPGDLGPVGYQGMKGE----------- 303
           GP G  G+PG  G  G+PG PG KG    G  G+ GD G VG QG  G            
Sbjct: 208 GPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCL 267

Query: 304 -KGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKG------SPGFDGIQG 356
            KG +G KG  G  G  G  G++G  G+ G KGE G PG PG +G      SPGF G++G
Sbjct: 268 YKGEKGIKGIPGMVGLPGPPGRKGESGI-GAKGEKGIPGFPGPRGDPGSYGSPGFPGLKG 326

Query: 357 PPGPKGDPGAFGLKGEKGEPGADGEAGRPGS--------SGPSGDEGQPGE--------- 399
             G  GDPG FGL G KG+PG  G  G PG          GP GD G PG          
Sbjct: 327 ELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGP 386

Query: 400 PGPPGEKGEAGDE-----GNPGPDGAPGERGGPGERG----PRGTPGTRGPRGDPGEAGP 450
           PGPPG  G  G+      G PGP G PG  G PGE G    P   PG  G  G PG  G 
Sbjct: 387 PGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGA 446

Query: 451 QGDQGREGP------VGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGA-PGPAGPPGDPG 503
            G QG  G       VG PG  G  G +GP G RG +G  G+EG     PGP GPPG PG
Sbjct: 447 PGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPG 506

Query: 504 LMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN--ND 561
           L G +G  G  G         PG+ G +G PG  G +G PGL G  G +G PG+     D
Sbjct: 507 LPGRQGSKGDLG--------LPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGD 558

Query: 562 IAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592
           +    VKG KG RGP+GP G PG  G  G D
Sbjct: 559 MVVSRVKGHKGERGPDGPPGFPGQPGSHGRD 589



 Score =  259 bits (663), Expect = 7e-69
 Identities = 157/375 (41%), Positives = 187/375 (49%), Gaps = 48/375 (12%)

Query: 252  CQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGE------KG 305
            C    G  G +G PG +G RG PG PG  G +G PG PGD G  G +G  GE      +G
Sbjct: 1095 CPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRG 1154

Query: 306  SRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCK--GSPGFDGIQGPPGPKGD 363
             +G+ G  GP G KG  G  G++G+ G+KG+ G  G  G    G PG  GI G  G +GD
Sbjct: 1155 LQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGD 1214

Query: 364  PGAFGL-----KGEKGEPGADGEAGRPGSSGPSG----DEGQPGEPGPPGEKGEAGDEGN 414
            PG+ G+     +G+KG PG  G +G PG +G +G    D   PG PG  G  G  G  G 
Sbjct: 1215 PGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGA 1274

Query: 415  PGPDGAPGE----RGGPGE---RGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPG 467
            PGP G PG     RG PG+    GP G PG  GP G  G  G  G  G++GPVG PG  G
Sbjct: 1275 PGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQG 1334

Query: 468  EAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGD----------PGLMGERGEDGPAGNG 517
              G  GP G +G  GPPG +G  G PGP G PG           PGL G  G  GP   G
Sbjct: 1335 PHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGP--EG 1392

Query: 518  TEGFPGF--PGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRG 575
              G PG   P  PG +G PG++G +G  G+ G  G  G  GD   D          GY G
Sbjct: 1393 AMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGED----------GYPG 1442

Query: 576  PEGPQGPPGHQGPPG 590
              GP GP G  GP G
Sbjct: 1443 GPGPPGPIGDPGPKG 1457



 Score =  259 bits (662), Expect = 9e-69
 Identities = 174/453 (38%), Positives = 203/453 (44%), Gaps = 108/453 (23%)

Query: 247 CCSFECQP---ARGPPGL------------------RGDPGFEGERGKPGLPGEKGEAGD 285
           C    C P   +RGPPG                    G+ G  G+RG PG  G+KG+ G 
Sbjct: 52  CSVCHCVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGP 111

Query: 286 ------------PGRPGDLGPVGYQGMKGEKGSRGEK---------GSRGPKGYKGEKGK 324
                       PG PG  GP G  GM G  GSRG+          G  GP G+ GEKG+
Sbjct: 112 TGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGE 171

Query: 325 RG-----IDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGAD 379
           +G     +  V G++G+ G PGLPG  GS G  G  GP G  G+PG  G  G+ G PG  
Sbjct: 172 KGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLK 231

Query: 380 GE--AGRPGSSGPSGDEGQPGEPGP------------PGEKGEAGDEGNPGPDGAPGERG 425
           G    G  G  G  G+ GQ G PGP             GEKG  G  G  G  G PG +G
Sbjct: 232 GNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKG 291

Query: 426 --GPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGP 483
             G G +G +G PG  GPRGDPG  G  G  G +G +G+ GDPG  G IGPKG  G+ G 
Sbjct: 292 ESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGH 351

Query: 484 PGSEGARGAP-----GPAGPPGDPGLMGERGEDGPAG------------------NGTEG 520
           PG  G    P     GP G PG PG  GE G+ GP G                   G +G
Sbjct: 352 PGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQG 411

Query: 521 FPGFPGYPGNRG-------APGINGTKGYPGLKGDEGEAGDPGD-----DNNDIAPRGVK 568
           FPG PG PG  G       APG  G  G PGL G  G  G PG         +  P+G+K
Sbjct: 412 FPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIK 471

Query: 569 GAKGYRGPEGPQG----------PPGHQGPPGP 591
           G  G  G  GP+G           PG  GPPGP
Sbjct: 472 GKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGP 504



 Score =  251 bits (641), Expect = 2e-66
 Identities = 167/423 (39%), Positives = 191/423 (45%), Gaps = 95/423 (22%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG-- 314
           G PG RGDPG  G  G PGL GE G  GDPG  G +GP      KG+ G+RG  G  G  
Sbjct: 305 GFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGP------KGDPGNRGHPGPPGVL 358

Query: 315 ---PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPG--FDGIQGPPGPKGDPGAFGL 369
              P   KG  G  G  G  G  G++G PG PG  G PG    G+ GPPGP+G PG  GL
Sbjct: 359 VTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGL 418

Query: 370 KGEKGEPG----ADGEAGRPGSSG------------------------PSGDEGQPGEPG 401
            GE G PG    A G+ G+PGS G                        P G +G+ G PG
Sbjct: 419 PGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPG 478

Query: 402 PPGEKGEAGDEG----------NPGPDGAPGERGG------------------PGERGPR 433
             G KGE G+EG           PGP G PG +G                   PG  GP 
Sbjct: 479 GRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPP 538

Query: 434 GTPGTRGPRGDPGEAGPQGD------------QGREGPVGVPGDPGEAGPIGPKGYRGDE 481
           G PG  G  G PG  G +GD            +G +GP G PG PG  G  G  G +GD 
Sbjct: 539 GLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDP 598

Query: 482 GPPG-----SEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGI 536
           GPPG     + G +G PGP GPPG  G +G  G   P   G  G PG PG+PG RG  G+
Sbjct: 599 GPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGL 658

Query: 537 NGTKG--------YPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGP 588
            G KG        YPG  G  G  G PG       P+G  G  G  G +G  G PG    
Sbjct: 659 KGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFP-GPQGAPGLSGSDGHKGRPGTPGTAEI 717

Query: 589 PGP 591
           PGP
Sbjct: 718 PGP 720



 Score =  239 bits (610), Expect = 1e-62
 Identities = 149/345 (43%), Positives = 166/345 (48%), Gaps = 55/345 (15%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            GPPG  G PG  G+ G PGL G+ GE GDPG  G  G  G  G  G KG  G  G  G  
Sbjct: 1121 GPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLH 1180

Query: 317  GYKGEKGKRGIDGVD--GVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKG 374
            G KG+KG +G  G+   G  G +G PGL G +G PG  GI  PPGP+G  G  G  G  G
Sbjct: 1181 GLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGIS-PPGPRGKKGPPGPPGSSG 1239

Query: 375  EPGADGEAGR----------PGSSGPSGDEGQPGEPGPPGE-------KGEAGDEGNPGP 417
             PG  G  GR          PG  GP G +G  G PGPPG        +GE GD G PGP
Sbjct: 1240 PPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGP 1299

Query: 418  DGAPGERGGPGERG---PRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGP 474
             G PG  G PG +G     G  G +GP G PG  GP G  G  G  G+PG PG  GP G 
Sbjct: 1300 PGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGL 1359

Query: 475  KGYRGDEGPP-------------------GSEGARGAPGPAGPPG-----DPGLMGERGE 510
             G RG+ GPP                   G EGA G PG  GP G     +PGL G RG 
Sbjct: 1360 PGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGV 1419

Query: 511  DG-------PAGNGTEGFPGFPGYPGNRGAPGINGTKGY-PGLKG 547
            DG       P   G  G  G+PG PG  G  G  G KG+ PG  G
Sbjct: 1420 DGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGFGPGYLG 1464



 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 44/118 (37%), Positives = 50/118 (42%), Gaps = 34/118 (28%)

Query: 251  ECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310
            +C    G PG  G  G EG  G PG+ G  G    PG  G+       G+ G +G  G  
Sbjct: 1374 DCPRIPGLPGAPGMRGPEGAMGLPGMRGPSG----PGCKGE------PGLDGRRGVDGVP 1423

Query: 311  GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFG 368
            GS GP G KG+             GE GYPG P            GPPGP GDPG  G
Sbjct: 1424 GSPGPPGRKGD------------TGEDGYPGGP------------GPPGPIGDPGPKG 1457



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 25/59 (42%), Positives = 31/59 (52%), Gaps = 17/59 (28%)

Query: 256  RGP--PGLRGDPGFEGERG------KPGLPGEKGEAGDPGRP---------GDLGPVGY 297
            RGP  PG +G+PG +G RG       PG PG KG+ G+ G P         GD GP G+
Sbjct: 1400 RGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGF 1458


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score =  298 bits (764), Expect = 1e-80
 Identities = 173/377 (45%), Positives = 197/377 (52%), Gaps = 42/377 (11%)

Query: 257  GPPGLRGDPGFEGERGKPGLPG------EKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310
            GPPG  G  G EG++G  G PG      +KG+AG PG+PG  GP G+ G  G  G++G +
Sbjct: 1064 GPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRR 1123

Query: 311  GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCK------------GSPGFDGIQGP- 357
            G  G  G KG+ G RG  GV G  G  G PG PG K            G+PG  G QGP 
Sbjct: 1124 GPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPT 1183

Query: 358  --------PGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEA 409
                    PG  G PGA G KGE+G+ G  G  G PG  GP GD G+ G+ GP G  G  
Sbjct: 1184 GSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPP 1243

Query: 410  GDEGNPGPDGAPGE---RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDP 466
            G +G PG DGA G     G PG+ GP G PG  G  G PGE G  GD G  GP G  G+P
Sbjct: 1244 GKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEP 1303

Query: 467  GEAGP---IGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-------N 516
            G  GP    GP G+ G EG  G +GA+G PGP GPPG  G MG RG  G  G        
Sbjct: 1304 GAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIP 1363

Query: 517  GTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN--NDIAPRGVKGAKGYR 574
            G  G PG  G PG  G PG  G  G PGLKGD G  G+ G       I P G  G KG +
Sbjct: 1364 GPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQ 1423

Query: 575  GPEGPQGPPGHQGPPGP 591
            G  G QGPPG +G PGP
Sbjct: 1424 GLPGVQGPPGPKGDPGP 1440



 Score =  296 bits (758), Expect = 7e-80
 Identities = 168/369 (45%), Positives = 199/369 (53%), Gaps = 34/369 (9%)

Query: 255  ARGPPGLRGDPGFEGERG------KPGLPGEKGEAGDPGRPG---DLGPVGYQGMKGEKG 305
            A+GPPG  G PG+ G RG        GL GEKGE G+ G PG   D+G  G QG  G  G
Sbjct: 696  AQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPG 755

Query: 306  SRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPG 365
             RGE G  GPKG  G+ G+ G  G  G KG++G PGLPG  G PG  G  G PGP G  G
Sbjct: 756  PRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIG 815

Query: 366  AFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERG 425
              G  G+ G+PG +GE G PGS G  G  G  G+PGP G+ G+ G  G PG  G PG +G
Sbjct: 816  EKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQG 875

Query: 426  GPGERGPRGTPGTRGPRGDP------GEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRG 479
             PG  GP+G PG +G  G P      GE G QG  G  GP GV G  G+ G +GP G RG
Sbjct: 876  PPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERG 935

Query: 480  DEGPPGSEGARGAP---GPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGI 536
              GPPG  G +G P   G  G  G+ G  G  G++GPA  G  GFPG  G PG+ G  G+
Sbjct: 936  PPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPA--GLRGFPGPKGGPGDPGPTGL 993

Query: 537  NGTKGYPGLKGDEGEAGD------------PGDDNND--IAPRGVKGAKGYRGPEGPQGP 582
             G KG PG  G  G  G+            PG   ++  + P G KG++G RGP GP G 
Sbjct: 994  KGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGK 1053

Query: 583  PGHQGPPGP 591
             G  GP GP
Sbjct: 1054 DGIPGPLGP 1062



 Score =  292 bits (747), Expect = 1e-78
 Identities = 170/379 (44%), Positives = 203/379 (53%), Gaps = 42/379 (11%)

Query: 256  RGPPGL---RGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGY---QGMKGEKGSRGE 309
            +GPPG    +G PG +G+ G+PG PG++GE G  G+ G  GP G    QG  GE G  GE
Sbjct: 874  QGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGE 933

Query: 310  KGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGL 369
            +G  GP G  GE+G  G++G +G KGE+G PG  G +G  G  G  GP G  GDPG  GL
Sbjct: 934  RGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGL 993

Query: 370  KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPG---------PPGEKGEAGDEGNPGP--- 417
            KG+KG PG  G  G PG  GP G  G  G PG         P G+KG  G+ G PGP   
Sbjct: 994  KGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGK 1053

Query: 418  DGAPGERG--------GP----GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGD 465
            DG PG  G        GP    G++G  G PG +G +GD G+AGP G  G  GP G PG 
Sbjct: 1054 DGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGP 1113

Query: 466  PG------EAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGT 518
            PG        GP G  G +GD+G  G  G  G PG  G PG PG  GE G+ G  G +G 
Sbjct: 1114 PGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGA 1173

Query: 519  EGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIA-----PRGVKGAKGY 573
             G  G  G  G+ G PG+ G  G PG  G++GE GD GD     A     P+G  G KG 
Sbjct: 1174 PGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGD 1233

Query: 574  RGPEGPQGPPGHQGPPGPD 592
             GP G  GPPG +GPPG D
Sbjct: 1234 SGPSGAAGPPGKKGPPGED 1252



 Score =  290 bits (741), Expect = 6e-78
 Identities = 159/350 (45%), Positives = 191/350 (54%), Gaps = 15/350 (4%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            G PG+ G PG +G  G PG  G  GE G  G PG  GP GY G +G KG+ G +G +G K
Sbjct: 668  GNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEK 727

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376
            G KGE G  G  G  G+KG+ G PG PG +G  G +G +G  G  G+ G  G  GEKG+ 
Sbjct: 728  GEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKL 787

Query: 377  GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436
            G  G  G PG  GP G  G PG  GP GEKG++G  G PG +G  G  G  GERG  G  
Sbjct: 788  GVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGAT 847

Query: 437  GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGA---P 493
            G  GP+GD G+ G  G  G +G  G+ G PG  GP GP G++G +G PG  G RG     
Sbjct: 848  GQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQ 907

Query: 494  GPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGINGTKGY------PGLK 546
            G  GPPG  G++G +G+ G  G  G  G PG PG PG +G PG+ G +G       PG  
Sbjct: 908  GQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPL 967

Query: 547  GDEGEAG-----DPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
            G EG AG      P     D  P G+KG KG  GP G  G PG +GP GP
Sbjct: 968  GKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGP 1017



 Score =  287 bits (735), Expect = 3e-77
 Identities = 168/416 (40%), Positives = 197/416 (47%), Gaps = 83/416 (19%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            GPPG  G+ G  G  G PG PG  G  G  G PG LGP+G +G  G+ G  G +G RGP 
Sbjct: 776  GPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPP 835

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPG---PKGDPGAFGLKGEK 373
            G +GE+G+ G  G  G KG++G  G PG  G  G  G+QGPPG   PKG PG  G  G  
Sbjct: 836  GSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRP 895

Query: 374  GEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPG----- 428
            G PG  GE G  G +GP G  G  G  G  GE G  G+ G PGP G PGE+G PG     
Sbjct: 896  GHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGRE 955

Query: 429  ----ERGP------------RGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPI 472
                E GP            RG PG +G  GDPG  G +GD+G  GPVG  G PGE GP+
Sbjct: 956  GAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPL 1015

Query: 473  GP---------------------KGYRGDEGPPGSEGARGAPGP---------------- 495
            GP                     KG RG+ GPPG  G  G PGP                
Sbjct: 1016 GPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEE 1075

Query: 496  --------------------AGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAP 534
                                AGPPG PG+ G  G  GP G +G +G  G PG  G +G  
Sbjct: 1076 GDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDD 1135

Query: 535  GINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
            G+ G  G  G  G +G  G PG +  ++   G  G  G  GP GPQGP G +G PG
Sbjct: 1136 GVRGFVGVIGPPGLQGLPGPPG-EKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPG 1190



 Score =  286 bits (731), Expect = 9e-77
 Identities = 174/364 (47%), Positives = 189/364 (51%), Gaps = 35/364 (9%)

Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGD------PGRPGD------LGPVGYQGMKG 302
           ARG PG  G  G  G  G PGLPGEKG+ GD      PG PG+       GP G  G  G
Sbjct: 537 ARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAG 596

Query: 303 EKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKG 362
           E G RG  G RG  G  G  G  GIDG  G KG +G PG PG  G  G  G QG PGP+ 
Sbjct: 597 EPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQ- 655

Query: 363 DPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPG 422
             G  G  GEKG PG  G  G PGS GP    G PG  GP GEKG  G  G+ GP G PG
Sbjct: 656 --GLIGTPGEKGPPGNPGIPGLPGSDGPL---GHPGHEGPTGEKGAQGPPGSAGPPGYPG 710

Query: 423 ERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDP---GEAGPIGPK---G 476
            RG  G  G RG  G +G +G+ G  G +GD G +G  G PG P   GE GP GPK   G
Sbjct: 711 PRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAG 770

Query: 477 YRGDEGPPGSEGAR---GAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFPGYPG 529
             G+EGPPGS G +   G PG  G PG PG  G  G  GP G     G  G  G PG  G
Sbjct: 771 QAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEG 830

Query: 530 NRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGP---EGPQGPPGHQ 586
            RG PG  G +G PG  G  G  GD G D     P G KG  G +GP    GP+GPPGHQ
Sbjct: 831 ERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIP-GEKGLPGLQGPPGFPGPKGPPGHQ 889

Query: 587 GPPG 590
           G  G
Sbjct: 890 GKDG 893



 Score =  283 bits (725), Expect = 4e-76
 Identities = 168/407 (41%), Positives = 201/407 (49%), Gaps = 74/407 (18%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
           GP GL G PG  G  G PGL GE+G  G  G  G  GP G  G  G+ G  G  G+RG  
Sbjct: 482 GPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLP 541

Query: 317 GYKGEKGKRGIDGVDGVKGE------MGYPGLPGCKGSPGFDGIQGPPGPKG---DPGAF 367
           G  G KG RG DG+ G+ GE       G+ G PG  G  G  G +GPPGP G   +PG  
Sbjct: 542 GDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPR 601

Query: 368 GLKGEKGEPGADGE---AGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDG---AP 421
           GL G +G PG  G     G  G+ G  G+ G PGEPGPPG++G  G +G PGP G    P
Sbjct: 602 GLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTP 661

Query: 422 GERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK------ 475
           GE+G PG  G  G PG+ GP G PG  GP G++G +GP G  G PG  GP G K      
Sbjct: 662 GEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNR 721

Query: 476 ---------------------GYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPA 514
                                G +GD+G PG+ G RG  GP GP G  G  GE G  G A
Sbjct: 722 GLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSA 781

Query: 515 GN----GTEGFPGFPGYPGNRGA---------------------PGINGTKGYPGLKGDE 549
           G     G  G PG+PG PG +G+                     PG+ G +G PG +G+ 
Sbjct: 782 GEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGER 841

Query: 550 ------GEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
                 G+ G  GD   D AP G+ G KG  G +GP G PG +GPPG
Sbjct: 842 GQPGATGQPGPKGDVGQDGAP-GIPGEKGLPGLQGPPGFPGPKGPPG 887



 Score =  282 bits (722), Expect = 1e-75
 Identities = 162/368 (44%), Positives = 191/368 (51%), Gaps = 37/368 (10%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            RGPPG  G PG   E+G PGL G +G  G+ G PG LG  G  G++G  G +G  G  GP
Sbjct: 934  RGPPGPPGPPG---EQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGP 990

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375
             G KG+KG  G  G +G  GE G  G  G  G PG  G +GP GP G  G+ G +G  G 
Sbjct: 991  TGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGP 1050

Query: 376  PGADG------EAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGE 429
             G DG        G PG++GPSG+EG  G+ G PG KG  GD+G+ GP G PG RG  G 
Sbjct: 1051 TGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGH 1110

Query: 430  RGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGA 489
             GP G  G +G RG PG  G +GD G  G VGV G PG  G  GP G +G+ G  GS G 
Sbjct: 1111 PGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGP 1170

Query: 490  RGAPGPAGPP---------------GDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAP 534
             GAPGP GP                G PG +GE+GE G AG+   G PG PG PG +G  
Sbjct: 1171 HGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGD--PGPPGAPGIPGPKGDI 1228

Query: 535  GINGTKGYPGLKGDEGEAGDPGDDN-----------NDIAPRGVKGAKGYRGPEGPQGPP 583
            G  G  G  G  G  G+ G PG+D             D+ P G  G  G  G  G +G P
Sbjct: 1229 GEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDP 1288

Query: 584  GHQGPPGP 591
            G  G PGP
Sbjct: 1289 GDVGGPGP 1296



 Score =  282 bits (721), Expect = 1e-75
 Identities = 162/353 (45%), Positives = 191/353 (54%), Gaps = 21/353 (5%)

Query: 256  RGPPGLRGDPGFEG---ERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKG---EKGSRGE 309
            RGP G  G PG +G    RG PGL G+KG+ G  G  G +GP G QG+ G   EKG  G+
Sbjct: 1105 RGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGD 1164

Query: 310  KGSRGPKGYKGEKGKRG---IDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366
             GS GP G  G +G +G    +G  G+ G +G PG  G KG  G  G  GPPG  G PG 
Sbjct: 1165 VGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGP 1224

Query: 367  FGLKGEKGEPGADGEAGRPGSSGPSGDEGQ---------PGEPGPPGEKGEAGDEGNPGP 417
             G  GEKG+ G  G AG PG  GP G++G          PG+ GPPG+ G +G +G+PG 
Sbjct: 1225 KGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGE 1284

Query: 418  DGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY 477
             G PG+ GGPG  G  G PG  GP G  G +G  G +GREG  G  G+PG  GP G  G 
Sbjct: 1285 KGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGP 1344

Query: 478  RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGIN 537
             G  GPPG  G  G  G  GP G+PGL+G  G+ GP   G  G  G PG  G+ G  G  
Sbjct: 1345 MGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPP--GPLGPSGLPGLKGDTGPKGEK 1402

Query: 538  GTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
            G  G  GL G  GEAG+ GD       +G  G KG  GP GP G  GH GPPG
Sbjct: 1403 GHIGLIGLIGPPGEAGEKGDQGLP-GVQGPPGPKGDPGPPGPIGSLGHPGPPG 1454



 Score =  280 bits (715), Expect = 6e-75
 Identities = 162/370 (43%), Positives = 187/370 (50%), Gaps = 39/370 (10%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            GP G  GDPG  G +G  G PG  G  G PG  G LGP G  G+ G+ GS G  G  G K
Sbjct: 980  GPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKK 1039

Query: 317  GYKGEKGKRGIDGVDGV---------------------KGEMGYPGLPGCKGS------P 349
            G +GE+G  G  G DG+                     KG++G PG  G KG       P
Sbjct: 1040 GSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPP 1099

Query: 350  GFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE---PGPPGEK 406
            G  GI+GP G  G PGA G +G +G PG  G+ G  G  G  G  G PG    PGPPGEK
Sbjct: 1100 GQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEK 1159

Query: 407  GEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDP 466
            GE GD G+ GP GAPG RG  G  G  GTPG  G  G PG  G +G++G  G  G PG P
Sbjct: 1160 GEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAP 1219

Query: 467  GEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN----GTEGFP 522
            G  GP G  G +GD GP    GA G PG  GPPG+ G  G  G  G  G+    G  G  
Sbjct: 1220 GIPGPKGDIGEKGDSGP---SGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVS 1276

Query: 523  GFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPG--DDNNDIAPRGVKGAKGYRGPEGPQ 580
            G  G PG +G PG  G  G PG  G+ G  G PG    +  +   G +G KG +G  GP 
Sbjct: 1277 GIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPD 1336

Query: 581  GPPGHQGPPG 590
            GPPG  GP G
Sbjct: 1337 GPPGRTGPMG 1346



 Score =  274 bits (700), Expect = 4e-73
 Identities = 173/421 (41%), Positives = 198/421 (47%), Gaps = 86/421 (20%)

Query: 256  RGPPGLRGDPGFEGERGKPG------------LPGEKGEAGDP------GRPGDLGPVGY 297
            +G PGL G  G +GE G PG             PG KG  GDP      G  G  GPVG 
Sbjct: 946  QGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGA 1005

Query: 298  QGMKGEKGS---------RGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGS 348
             G  GE+G           G+ GS GP G  G+KG RG  G  G  G+ G PG  G  G 
Sbjct: 1006 NGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGP 1065

Query: 349  PGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE--------- 399
            PG  G  G  G KGD GA G KG KG+ G  G  G+PG  GP+G  G PG          
Sbjct: 1066 PGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGP 1125

Query: 400  ---------------------------PGPPGEKGEAGDEGNPGPDGAPGERGGPGERGP 432
                                       PGPPGEKGE GD G+ GP GAPG RG  G  G 
Sbjct: 1126 PGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGS 1185

Query: 433  RGTP------------GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD 480
             GTP            G +G RGD G+ GP G  G  GP G  G+ G++GP G  G  G 
Sbjct: 1186 EGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGK 1245

Query: 481  EGPPGSEGARGA------PGPAGPPGDPGLMGERGEDGPAGN----GTEGFPGFPGYPGN 530
            +GPPG +GA+G+      PG  GPPGDPG+ G  G  G  G+    G  G PG  G PG 
Sbjct: 1246 KGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGA 1305

Query: 531  RGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
             G PG  G  G+ G +G EGE G  G+   D  P G  G  G RGP G  GP G +G PG
Sbjct: 1306 PGPPGKRGPSGHMGREGREGEKGAKGEPGPD-GPPGRTGPMGARGPPGRVGPEGLRGIPG 1364

Query: 591  P 591
            P
Sbjct: 1365 P 1365



 Score =  271 bits (694), Expect = 2e-72
 Identities = 170/414 (41%), Positives = 199/414 (48%), Gaps = 73/414 (17%)

Query: 250 FECQPARGPPGLRGDPG-------FEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKG 302
           F+  P  G  G +G+P        FEG  G PG  G  G +G PG PG  G  G  G  G
Sbjct: 366 FQIFPGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAG 425

Query: 303 EKGSRGEKGSRGPKG-------------YKGE--------------------KGKRGIDG 329
             G  G  G RGP G             +KG                     KG  G  G
Sbjct: 426 LPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVG 485

Query: 330 VDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSG 389
           + G  G +G PG PG KG  G +G QGP G +G  G  G  G+ G PGADG  G PG +G
Sbjct: 486 LTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTG 545

Query: 390 PSGDEGQPGEPGPPGEKGEAGDEGN---PGPDGAPGERGGPGERGPRGTPGTRGPRGDPG 446
           P GD G  G PG PGEKG+ GD G+   PGP G  GERG  G  GP G  G  GPRG  G
Sbjct: 546 PKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLG 605

Query: 447 EAGPQGDQGREGPVGVPG---------DPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAG 497
             G  G  GR G  G+ G          PGE GP G +G  G +G PG +G  G PG  G
Sbjct: 606 PRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKG 665

Query: 498 PPGDPGLMGERGEDGPAGN----------GTEGFPGF---PGYPGNRGAPGINGTKGYPG 544
           PPG+PG+ G  G DGP G+          G +G PG    PGYPG RG  G +G +G  G
Sbjct: 666 PPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQG 725

Query: 545 LKGDEGEAGDPG--DDNNDIAPRGVKGAKGYRGPEGPQGP------PGHQGPPG 590
            KG++GE G PG   D      +G  GA G RG +GP+GP       G +GPPG
Sbjct: 726 EKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPG 779



 Score =  266 bits (681), Expect = 6e-71
 Identities = 165/410 (40%), Positives = 191/410 (46%), Gaps = 81/410 (19%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPG----------------------------- 287
           GPPG  GDPG  G  G PG+PG  G  G PG                             
Sbjct: 410 GPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAV 469

Query: 288 -------------------RPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGID 328
                              RPG +G  G+ G+KGE+G+ G +G RG +G  G  G+ G  
Sbjct: 470 LQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKM 529

Query: 329 GVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSS 388
           G  G  G  G PG  G KG  GFDG+ G PG KG  G FG  G+ G PG DGE G  G  
Sbjct: 530 GRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPP 589

Query: 389 GPSGDEGQPGEPGPPGEKGEAGDEGNPGP---DGAPGERGG---PGERGPRGTPGTRGPR 442
           GP+G  G+PG  G  G +G  G  G PG    DGAPG +G    PGE GP G  G  G +
Sbjct: 590 GPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQ 649

Query: 443 GDPGEAGPQGDQGREGPVG---VPGDPGEAGPIG------PKGYRGDEGPPGSEGARGAP 493
           G PG  G  G  G +GP G   +PG PG  GP+G      P G +G +GPPGS G  G P
Sbjct: 650 GLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYP 709

Query: 494 GPAGPPGDPGLMGERGEDGPAGNGTEGFPGF------------PGYPGNRGAPGINGTKG 541
           GP G  G  G  G +GE G    G +GFPGF            PG PG RG  G  G KG
Sbjct: 710 GPRGVKGTSGNRGLQGEKGE--KGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKG 767

Query: 542 YPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
             G  G+EG  G  G+        GV G  GY G  GP+G  G  GP GP
Sbjct: 768 QAGQAGEEGPPGSAGEKGK----LGVPGLPGYPGRPGPKGSIGFPGPLGP 813



 Score =  263 bits (671), Expect = 8e-70
 Identities = 151/326 (46%), Positives = 168/326 (51%), Gaps = 13/326 (3%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            +GP G  G PG  G  G+PG  GEKGE GD G PG   P G  G+ G KG  GEKG  GP
Sbjct: 1180 QGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPG---PPGAPGIPGPKGDIGEKGDSGP 1236

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGC---KGSPGFDGIQGPPGPKGDPGAFGLKGE 372
             G  G  GK+G  G DG KG +G  GLPG     G PG  GI G PG KGDPG  G  G 
Sbjct: 1237 SGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGP 1296

Query: 373  KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGP 432
             G  G  G  G PG  GPSG  G+ G  G  G KGE G +G PG  G  G RG PG  GP
Sbjct: 1297 PGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGP 1356

Query: 433  RGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGA 492
             G  G  GP G+PG  G  G  G  GP+G  G PG  G  GPKG   ++G  G  G  G 
Sbjct: 1357 EGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKG---EKGHIGLIGLIGP 1413

Query: 493  PGPAGPPGDPGLMGERGEDGPAGN----GTEGFPGFPGYPGNRGAPGINGTKGYPGLKGD 548
            PG AG  GD GL G +G  GP G+    G  G  G PG PG  G  G  G+KG PG  G 
Sbjct: 1414 PGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGP 1473

Query: 549  EGEAGDPGDDNNDIAPRGVKGAKGYR 574
             G+ G  G      AP  + G +  R
Sbjct: 1474 RGDTGPAGPPGPPGAPAELHGLRRRR 1499



 Score =  236 bits (602), Expect = 8e-62
 Identities = 134/305 (43%), Positives = 154/305 (50%), Gaps = 23/305 (7%)

Query: 255  ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314
            A G  G RGD G  G  G PG+PG KG+ G+ G  G  G  G  G KG  G  G KGS G
Sbjct: 1200 AVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVG 1259

Query: 315  PKGYKGE---KGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKG 371
            P G  G+    G  G+ G+DG  GE G PG  G  G PG  G  G PGP G  G  G  G
Sbjct: 1260 PTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMG 1319

Query: 372  EKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERG 431
             +G  G  G  G PG  GP G  G  G  GPPG  G  G  G PGP G PG  G PG+ G
Sbjct: 1320 REGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMG 1379

Query: 432  PRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARG 491
            P G  G  G  G  G+ GP+G++G  G +G+ G PGEAG       +GD+G P   G +G
Sbjct: 1380 PPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGE------KGDQGLP---GVQG 1430

Query: 492  APGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGE 551
             PGP G PG PG +G  G  GP           PG  G  G  G  G+ G  G +GD G 
Sbjct: 1431 PPGPKGDPGPPGPIGSLGHPGP-----------PGVAGPLGQKGSKGSPGSMGPRGDTGP 1479

Query: 552  AGDPG 556
            AG PG
Sbjct: 1480 AGPPG 1484



 Score =  144 bits (364), Expect = 3e-34
 Identities = 84/196 (42%), Positives = 94/196 (47%), Gaps = 30/196 (15%)

Query: 255  ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKG------------ 302
            A GPPG RG  G  G  G+ G  G KGE G  G PG  GP+G +G  G            
Sbjct: 1305 APGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPG 1364

Query: 303  ---EKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGY---------PGLPGCKGSPG 350
               E G  G  G  GP G  G  G  G+ G  G KGE G+         PG  G KG  G
Sbjct: 1365 PVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQG 1424

Query: 351  FDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAG 410
              G+QGPPGPKGDPG  G  G  G PG       PG +GP G +G  G PG  G +G+ G
Sbjct: 1425 LPGVQGPPGPKGDPGPPGPIGSLGHPGP------PGVAGPLGQKGSKGSPGSMGPRGDTG 1478

Query: 411  DEGNPGPDGAPGERGG 426
              G PGP GAP E  G
Sbjct: 1479 PAGPPGPPGAPAELHG 1494



 Score =  103 bits (257), Expect = 8e-22
 Identities = 78/213 (36%), Positives = 90/213 (42%), Gaps = 49/213 (23%)

Query: 408 EAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPG 467
           E GD+   GPD    E     +       G +G +G+P  A  +  Q  EGP G PG  G
Sbjct: 344 EEGDDSTMGPDFRAAEYPSRTQFQIFPGAGEKGAKGEP--AVIEKGQQFEGPPGAPGPQG 401

Query: 468 EAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGP--------AGNGTE 519
             GP GP G      PPG  G  G PGPAG PG PG+ G RG  G         AG   +
Sbjct: 402 VVGPSGPPG------PPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFK 455

Query: 520 GFP--------------------GFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN 559
           G P                    G PG  G  G PG  G  G+PGLKG+EG  G  G   
Sbjct: 456 GPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQG--- 512

Query: 560 NDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592
               PRG++      GP GP G  G  G PG D
Sbjct: 513 ----PRGLQ------GPHGPPGRVGKMGRPGAD 535



 Score = 78.6 bits (192), Expect = 3e-14
 Identities = 50/142 (35%), Positives = 64/142 (45%), Gaps = 25/142 (17%)

Query: 473 GPKGYRGD----------EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFP 522
           G KG +G+          EGPPG+ G +G  GP+GPPG PG  G+ G  GPAG      P
Sbjct: 373 GEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAG-----LP 427

Query: 523 GFPGYPGNRGAPGI---------NGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGY 573
           G PG  G RG PG           G+   P +   + +A         ++ +G  G  G 
Sbjct: 428 GIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQA-QAVLQQTQLSMKGPPGPVGL 486

Query: 574 RGPEGPQGPPGHQGPPGPDECE 595
            G  GP G PGH G  G +  E
Sbjct: 487 TGRPGPVGLPGHPGLKGEEGAE 508


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score =  297 bits (761), Expect = 3e-80
 Identities = 176/376 (46%), Positives = 202/376 (53%), Gaps = 40/376 (10%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            GPPG +G+PG  G+ G  G PG KG  GD G PG   P G +G  G  G  G+ GS G  
Sbjct: 1003 GPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG---PQGVEGPPGPSGVPGQPGSPGLP 1059

Query: 317  GYKGEKGKRGID-----GVDGVKGEMG---YPGLPGCKGS---PGFDGIQGPPGPKGDPG 365
            G KG+KG  GI      G+ G KGE G   YPG PG KGS   PG  G+ G PG KG PG
Sbjct: 1060 GQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPG 1119

Query: 366  AFGLKGEKGEPGADGEAGRPGSSG------PSGDEGQPGEPGPPGEKGEAGDEGNPGPDG 419
              G  G  G PG  G +G PG+ G      P G  G PG+PGPPGEKG+ G +G PGP G
Sbjct: 1120 LPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG 1179

Query: 420  APGERGGPG--ERGPRGTPGTRGPRGD---------PGEAGPQGDQGREGPVGV---PGD 465
              GE G PG    GP G PG  G +GD         PG  GP+G+ G  G  GV   PG 
Sbjct: 1180 QKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGP 1239

Query: 466  PGEAGPI--GPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPG 523
            PG  GP   GPKG  G +GPPG  G +G PGP GPPG PG  G +GE G  G    G PG
Sbjct: 1240 PGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQ--PGLPG 1297

Query: 524  FPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN--NDIAPRGVKGAKGYRGPEGPQG 581
             PG  G++G PG+ G  G PGL G +G+ G PG         P GV G+ G  G  G  G
Sbjct: 1298 LPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIG 1357

Query: 582  PPGHQGPPGPDECEIL 597
            PPG  G PGP    I+
Sbjct: 1358 PPGPPGLPGPSGQSII 1373



 Score =  294 bits (753), Expect = 3e-79
 Identities = 164/344 (47%), Positives = 190/344 (55%), Gaps = 25/344 (7%)

Query: 253  QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312
            Q   GPPG  G P   G+ G PGLPG+KG+ GDPG    +  +G  G+ G KG  G  G 
Sbjct: 1038 QGVEGPPGPSGVP---GQPGSPGLPGQKGDKGDPG----ISSIGLPGLPGPKGEPGLPGY 1090

Query: 313  RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372
             G  G KG  G  G+ G+ G  G  G PGLPG  G+P      GPPGPKG  G  G  G 
Sbjct: 1091 PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTP------GPPGPKGISGPPGNPGL 1144

Query: 373  KGEPGADGEAGRPGSSGPSGDEGQPGE---PGPPGEKGEAGDE--GNPGPDGAPGERGGP 427
             GEPG  G  G PG  GP G++G+PG+   PGP G+KGE G    GNPGP G PG  G  
Sbjct: 1145 PGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQK 1204

Query: 428  GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE 487
            G+ G  G PG  G  G  GE G  G  G +GP G PG PG A   GPKG  G +GPPG  
Sbjct: 1205 GDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALE-GPKGNPGPQGPPGRP 1263

Query: 488  GARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKG 547
            G +G PGP GPPG PG  G +GE G    G  G PG PG  G++G PG+ G  G PGL G
Sbjct: 1264 GFQGLPGPEGPPGLPGNGGIKGEKG--NPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNG 1321

Query: 548  DEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
             +G+ G PG         G+KG  G  G  GP+G PG  GPPGP
Sbjct: 1322 MKGDPGLPGVPGFP----GMKGPSGVPGSAGPEGEPGLIGPPGP 1361



 Score =  290 bits (743), Expect = 4e-78
 Identities = 177/409 (43%), Positives = 204/409 (49%), Gaps = 77/409 (18%)

Query: 255  ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMK------------- 301
            A GP G  G PG  G+ G  G PG KGE G  G PG  GP+G  G               
Sbjct: 870  APGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQG 929

Query: 302  --------GEKGSRGEKGSRGPK--------GYKGEKGKRGIDGVDGVKGEMGYPGLPGC 345
                    GEKGS+GE G  GP         G KGEKG+ G+ G+ GV G  GY GLPG 
Sbjct: 930  QPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD 989

Query: 346  KGSPGFD---GIQGPPGPKGDP---------GAFGLKGEKGEPGADGEAGRPGSSGPSGD 393
             G PG     G+ GPPGPKG+P         G  GLKG  G+ G  G  G  G  GPSG 
Sbjct: 990  PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049

Query: 394  EGQPGEPGPPGEKGEAGD--------EGNPGPDGAPGERGGPGERGPRGT---------P 436
             GQPG PG PG+KG+ GD         G PGP G PG  G PG  G +G+         P
Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLP 1109

Query: 437  GTRGPRGD------PGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSE--- 487
            GT G +G       PG  GP G +G  GP G PG PGE GP+G  G+ G  GPPG +   
Sbjct: 1110 GTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKP 1169

Query: 488  GARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFPGYPGNRGAPGINGTKGYP 543
            G  G PGPAG  G+PG  G  G  GP G    +G +G  G PG PGN G PG  G  G+ 
Sbjct: 1170 GQDGIPGPAGQKGEPGQPG-FGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFH 1228

Query: 544  GLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592
            G  G +G  G PG          ++G KG  GP+GP G PG QG PGP+
Sbjct: 1229 GFPGVQGPPGPPGSPG-----PALEGPKGNPGPQGPPGRPGFQGLPGPE 1272



 Score =  286 bits (733), Expect = 5e-77
 Identities = 167/351 (47%), Positives = 185/351 (52%), Gaps = 28/351 (7%)

Query: 257  GPPGLR--GDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314
            GPPGL   G PG  G  G PG PG  G  G PG PG  G  G+ G KGE G  G  G  G
Sbjct: 849  GPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPG 908

Query: 315  PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGS---PGFDGIQGPPGPKGDPGAFGLKG 371
            P G  G  G  G+ G DG++G+ G PG  G KGS   P   G+ GPPGP  DP   G KG
Sbjct: 909  PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEP---GLPGPPGPM-DPNLLGSKG 964

Query: 372  EKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERG 431
            EKGEPG     G PG SGP G +G PG+PG PG  G+ G  G PGP G PG  G PG  G
Sbjct: 965  EKGEPGL---PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIG 1021

Query: 432  PRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE-----GPPGS 486
            P   PG +G  GD G  GPQG +G  GP GVPG PG  G  G KG +GD      G PG 
Sbjct: 1022 P---PGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGL 1078

Query: 487  EGARGAPGPAGPPGDPGLMGERGEDG-------PAGNGTEGFPGFPGYPGNRGAPGINGT 539
             G +G PG  G PG+PG+ G  G+ G       P   G  G PGFPG PG  G  GI+G 
Sbjct: 1079 PGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGP 1138

Query: 540  KGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
             G PGL G+ G  G  G       P G KG  G  G  GP G  G  G PG
Sbjct: 1139 PGNPGLPGEPGPVGGGGHPGQP-GPPGEKGKPGQDGIPGPAGQKGEPGQPG 1188



 Score =  281 bits (720), Expect = 2e-75
 Identities = 167/374 (44%), Positives = 193/374 (51%), Gaps = 46/374 (12%)

Query: 252 CQPARGPPGLRGDPGFEGERGKPGLPGEKGEA-------------GDPGRPGDLGPVGYQ 298
           C+P  GPPG  G PG +G +G+ G+ G+KG+              G PG PG  GP G  
Sbjct: 451 CEP--GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSL 508

Query: 299 GMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMG-------------------Y 339
           G  G+KG +G+ G+ GPKG  G  G  G  G  G KGE G                    
Sbjct: 509 GFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGA 568

Query: 340 PGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE 399
           PGLPG  G+PG DG+ G PGPKG+PG    KGE+G PG  G  G PG+ GP G  G  G 
Sbjct: 569 PGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GP 627

Query: 400 PGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPR-GTPGTRGPRGDPGEAGPQGDQGREG 458
           PGP GEKG  G  GNPG  G PG +G PG+   + G PG  G  G  G+ G  GD G  G
Sbjct: 628 PGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPG 687

Query: 459 PVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NG 517
             G+PG PG  G  G  G  G  GPPG +G  G PGP G PG PG +G  G  GP G  G
Sbjct: 688 QPGLPGIPGSKGEPGIPGI-GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746

Query: 518 TEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPE 577
            +G PGF   PG  G PG+ G KG  G KGD G  G PG       P G  G  G  GP+
Sbjct: 747 PKGEPGF-ALPGPPGPPGLPGFKGALGPKGDRGFPGPPG-------PPGRTGLDGLPGPK 798

Query: 578 GPQGPPGHQGPPGP 591
           G  GP G  GP GP
Sbjct: 799 GDVGPNGQPGPMGP 812



 Score =  278 bits (711), Expect = 2e-74
 Identities = 167/385 (43%), Positives = 195/385 (50%), Gaps = 50/385 (12%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            RG PG+ G PG  G  G PGLPG+ G +G PG  G++G +G  G  G  G  G  G  G 
Sbjct: 862  RGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGL 921

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLP-----------GCKGSPGFDGIQGPPGPKGDP 364
            KG  G +G+ G+ G  G KG  G PGLP           G KG  G  G+ G PG  G  
Sbjct: 922  KGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPK 981

Query: 365  GAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEP---GPPGEKGEAGD---------E 412
            G  GL G+ G+PG  G+ G PG  GP G+ G PG+P   GPPG KG  GD         E
Sbjct: 982  GYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVE 1041

Query: 413  GNPGPDGAPGERGGPGERGPR-----------GTPGTRGPRGDPGEAGPQGDQGREGPVG 461
            G PGP G PG+ G PG  G +           G PG  GP+G+PG  G  G+ G +G VG
Sbjct: 1042 GPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVG 1101

Query: 462  VPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEG 520
             PG PG  G  G KG  G  G PG+ G  G  G +GPPG+PGL GE G  G  G+ G  G
Sbjct: 1102 DPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPG 1161

Query: 521  FPGFPGYPGNRGAPGINGTK--------------GYPGLKGDEGEAGDPGDDNNDIAPRG 566
             PG  G PG  G PG  G K              G PGL G +G+ G PG   N   P G
Sbjct: 1162 PPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLP-G 1220

Query: 567  VKGAKGYRGPEGPQGPPGHQGPPGP 591
             KG  G+ G  G QGPPG  G PGP
Sbjct: 1221 PKGEPGFHGFPGVQGPPGPPGSPGP 1245



 Score =  278 bits (710), Expect = 2e-74
 Identities = 163/379 (43%), Positives = 195/379 (51%), Gaps = 47/379 (12%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPG--RPGDLGPVGYQGMKGEKGSRGE----- 309
            G  GL GDPG  G+ G PG+PG KGE G PG   PG  GP G+ G+ G  G+ G      
Sbjct: 675  GDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIG 734

Query: 310  -KGSRGPKGYKGEKGKRGI--------------DGVDGVKGEMGYPGLPGCKGSPGFDGI 354
             +G  GP G+ G KG+ G                G  G KG+ G+PG PG  G  G DG+
Sbjct: 735  LEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGL 794

Query: 355  QGP---------PGPKGDPG--AFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPG-- 401
             GP         PGP G PG    G++G  G PG  G  G+PG  G  G++G PG PG  
Sbjct: 795  PGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLD 854

Query: 402  ---PPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREG 458
               PPGE+G  G  G PGP G PG  G PG+ G  G PGT+G  G  G  GP G  G  G
Sbjct: 855  VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPG 914

Query: 459  PVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG--- 515
              GVPG  G+ G  G  G  G  G  GS+G  G PGP GP  DP L+G +GE G  G   
Sbjct: 915  RSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPM-DPNLLGSKGEKGEPGLPG 973

Query: 516  -NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGA---K 571
              G  G  G+ G PG+ G PG++G  G PG  G +G  G PG     I P G+KG     
Sbjct: 974  IPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGL-IGPPGLKGTIGDM 1032

Query: 572  GYRGPEGPQGPPGHQGPPG 590
            G+ GP+G +GPPG  G PG
Sbjct: 1033 GFPGPQGVEGPPGPSGVPG 1051



 Score =  278 bits (710), Expect = 2e-74
 Identities = 166/357 (46%), Positives = 186/357 (52%), Gaps = 24/357 (6%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            G PGL G PG  G +G+PGLPG  G  G PG  G  GP G  G+ GE G  G  G  G  
Sbjct: 1101 GDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQP 1160

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD------PGAFGLK 370
            G  GEKGK G DG+ G  G+ G PG PG  G+PG  G+ G  G KGD      PG  GL 
Sbjct: 1161 GPPGEKGKPGQDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGLPGIPGNPGLP 1219

Query: 371  GEKGEPGADGEAGRPGSSGPSGD-----EGQPGEPGPPGEKGEAGDEGNPGPDGAPGERG 425
            G KGEPG  G  G  G  GP G      EG  G PGP G  G  G +G PGP+G PG  G
Sbjct: 1220 GPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPG 1279

Query: 426  GPGERGPRGTPGTRGP------RGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRG 479
              G +G +G PG  G       +GD G  G QG+ GR G  G+ GDPG  G  G  G +G
Sbjct: 1280 NGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKG 1339

Query: 480  DEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGT 539
              G PGS G  G PG  GPPG PGL G  G+      G  G PG PG PG +G PG  G 
Sbjct: 1340 PSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQ-SIIIKGDAGPPGIPGQPGLKGLPGPQGP 1398

Query: 540  KGYP---GLKGDEGEAGDPGDD--NNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
            +G P   G  GD G  G PG D         G+ G  G RG +GP GP G QGPPGP
Sbjct: 1399 QGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGP 1455



 Score =  275 bits (704), Expect = 1e-73
 Identities = 166/367 (45%), Positives = 188/367 (51%), Gaps = 52/367 (14%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPG---DLGPVG------YQGMKGEKGSR 307
            G PG +G PG  G  G PG PG KG +G PG PG   + GPVG        G  GEKG  
Sbjct: 1110 GTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKP 1169

Query: 308  GEKGSRGPKGYKGEKGKRG--------IDGVDGVKGEMGYPGLPGCKGSPG--------- 350
            G+ G  GP G KGE G+ G        + G+ G KG+ G PG+PG  G PG         
Sbjct: 1170 GQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHG 1229

Query: 351  FDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAG 410
            F G+QGPPGP G PG   L+G KG PG  G  GRPG  G  G EG PG PG  G KGE G
Sbjct: 1230 FPGVQGPPGPPGSPGP-ALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKG 1288

Query: 411  DEGNPGPDGAPG---ERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPG 467
            + G PG  G PG   ++G PG +G  G PG  G +GDPG  G  G  G +GP GVPG   
Sbjct: 1289 NPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGS-- 1346

Query: 468  EAGPIGPKGYRGDEGPPGSEGARGAP----GPAGPPGDPGLMGERGEDGPAGNGTEGFPG 523
             AGP G  G  G  GPPG  G  G      G AGPPG PG  G +G  GP   G +G PG
Sbjct: 1347 -AGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGP--QGPQGLPG 1403

Query: 524  FPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPP 583
              G PG+ G  G+ G  G  G KGD G  G PG              +G  GP GP G  
Sbjct: 1404 PTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPG-------------TRGLDGPPGPDGLQ 1450

Query: 584  GHQGPPG 590
            G  GPPG
Sbjct: 1451 GPPGPPG 1457



 Score =  274 bits (701), Expect = 3e-73
 Identities = 161/375 (42%), Positives = 189/375 (50%), Gaps = 43/375 (11%)

Query: 255  ARGPPGLR---GDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGM----------- 300
            A GP G R   G PG  G  G  GLPG KG+ G  G+PG +GP G  G+           
Sbjct: 770  ALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI 829

Query: 301  ------KGEKGSRGEKGSRGPKGY-----KGEKGKRGIDGVDGVKGEMGYPGLPGCKGSP 349
                   G  G  GEKG  GP G       GE+G  GI G  G  G  G PGLPG  G+ 
Sbjct: 830  PGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889

Query: 350  GFDGIQ---------GPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEP 400
            GF G +         GPPGP G PG  G+ G KG+ G  G+ G PG +G  G +G+PG P
Sbjct: 890  GFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLP 949

Query: 401  GPPGEK-----GEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQG 455
            GPPG       G  G++G PG  G PG  G  G +G  G PG  G  G PG  GP G +G
Sbjct: 950  GPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKG 1009

Query: 456  REGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG 515
                 G+PG PG  GP G KG  GD G PG +G  G PGP+G PG PG  G  G+ G  G
Sbjct: 1010 NP---GLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG 1066

Query: 516  NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRG 575
            +      G PG PG +G PG+ G  G PG+KG  G+ G PG      A +G  G  G+ G
Sbjct: 1067 DPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGA-KGQPGLPGFPG 1125

Query: 576  PEGPQGPPGHQGPPG 590
              GP GP G  GPPG
Sbjct: 1126 TPGPPGPKGISGPPG 1140



 Score =  271 bits (694), Expect = 2e-72
 Identities = 170/409 (41%), Positives = 194/409 (47%), Gaps = 75/409 (18%)

Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
           RG PGL G PG  G  G  G PG +G+ GD G PG  GP G +G  G  G  G  G  G 
Sbjct: 50  RGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGM 109

Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFG------- 368
            G+ G  G +GI G +G KGE G+PG      SPGF G+QGPPGP G PG  G       
Sbjct: 110 PGHDGAPGPQGIPGCNGTKGERGFPG------SPGFPGLQGPPGPPGIPGMKGEPGSIIM 163

Query: 369 --LKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPP----------------------- 403
             L G KG PG  G  G  G  GP+G  G  G PGPP                       
Sbjct: 164 SSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQ 223

Query: 404 ---GEKGEAGDEGNPGPDG-------------APGERGGPGERGPRGTPGTRGPRGDP-G 446
              GEKGE G +G PGP G               G++G PG+RGP G PG RGP G P G
Sbjct: 224 GPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGG 283

Query: 447 EAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD---EGPPGSEGARGAPGPAGPPGDPG 503
           E G +G+QG  G  G PG  GE G  G  G  GD    G PG +G +G  G  GPPG PG
Sbjct: 284 EKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPG 343

Query: 504 L----------MGERGEDG----PAGNGTEGFPGFPGYPGNRGAPG--INGTKGYPGLKG 547
           L          +GE+G  G    P   G  GFPG  G PG  G PG  + G  G PG  G
Sbjct: 344 LVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPG 403

Query: 548 DEGEAGDPGDDNNDI-APRGVKGAKGYRGPEGPQGPPGHQGPPGPDECE 595
           + G+ GD G     I  P G+ G  G  G  GP GP G   PP  + CE
Sbjct: 404 ERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICE 452



 Score =  270 bits (689), Expect = 7e-72
 Identities = 165/367 (44%), Positives = 187/367 (50%), Gaps = 31/367 (8%)

Query: 254 PARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGR----------PGDLGPVGYQGMKGE 303
           P  GPPG  G+ G +G  G PG PG  G  GDPG+          PG+ G  G  G+ G+
Sbjct: 623 PGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGD 682

Query: 304 KGSRGEKGSRGPKGYKGEKGKRGI--DGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361
            G  G+ G  G  G KGE G  GI   G  G KG  G PG PG  G+PG  G++GPPGP 
Sbjct: 683 PGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPP 742

Query: 362 GDPGAFGLKG--EKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGE---------KGEAG 410
           G PG  G  G    G PG  G  G  G+ GP GD G PG PGPPG          KG+ G
Sbjct: 743 GFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVG 802

Query: 411 DEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVG--VPGDPGE 468
             G PGP G PG   G G +GP G PG  GP G PG  G  G++G  GP G  VPG PGE
Sbjct: 803 PNGQPGPMGPPG-LPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGE 861

Query: 469 AGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGF 524
            G  G  G  G  GPPGS G  G  G +G PG  G MG  G  GP G     G  G PG 
Sbjct: 862 RGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGL 921

Query: 525 PGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGD-DNNDIAPRGVKGAKGYRGPEGPQGPP 583
            G  G +G PG+ G  G  G KG+ G  G PG  D N +  +G KG  G  G  G  GP 
Sbjct: 922 KGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPK 981

Query: 584 GHQGPPG 590
           G+QG PG
Sbjct: 982 GYQGLPG 988



 Score =  268 bits (686), Expect = 1e-71
 Identities = 168/395 (42%), Positives = 196/395 (49%), Gaps = 55/395 (13%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG-- 314
           G PGL G PG  G+ G PGLPG KGE G     G+ GP G  G+ G  G+ G  G  G  
Sbjct: 567 GAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFG 626

Query: 315 PKGYKGEKGKRGI------DGVDGVKGEMGY----PGLPGCKGSPGFDG---IQGPPGPK 361
           P G  GEKG +G+       G+ G KG+ G     PG PG  G+PG DG   + G PG  
Sbjct: 627 PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP 686

Query: 362 GDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAP 421
           G PG  G+ G KGEPG  G  G PG  GP G  G PG PG PG  G  G EG PGP G P
Sbjct: 687 GQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFP 745

Query: 422 GERGGPG-----ERGPRGTPGTRG---PRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIG 473
           G +G PG       GP G PG +G   P+GD G  GP G  GR G  G+PG  G+ GP G
Sbjct: 746 GPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNG 805

Query: 474 PKGYRGDEGPPG-----SEGARGAPGPAGPPGDPGLMGERGEDGPAG---------NGTE 519
             G  G  G PG       G  G PGP G PG  G+ GE+G+ GP G          G+ 
Sbjct: 806 QPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSP 865

Query: 520 GFPGFPGY---PGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN--------------NDI 562
           G PG PG    PG+ G PG  G  G+PG KG+ G  G PG                  D 
Sbjct: 866 GIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDD 925

Query: 563 APRGVKGAKGYRGPEGPQGPPGHQGPPGPDECEIL 597
             +G  G  G  G +G +G PG  GPPGP +  +L
Sbjct: 926 GLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960



 Score =  268 bits (685), Expect = 2e-71
 Identities = 168/384 (43%), Positives = 194/384 (50%), Gaps = 52/384 (13%)

Query: 257 GPPGLRGDPGFEGERGK------------PGLPGEKGEAGDPGRPGDLGPVGYQGMKGEK 304
           GPPG  G PG +GE+G+            PG PG  G  G  G PGD+  + + GMKG+K
Sbjct: 503 GPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDI--LTFPGMKGDK 560

Query: 305 GSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMG---YPGLPGCKGSPGFDGIQGPPGPK 361
           G  G  G+ G  G  G  G+ G+ G+ G KGE G   + G  G  G+PG  G+ G  GP 
Sbjct: 561 GELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPM 620

Query: 362 GDP--GAFGLKGEKGEPGADGEAGRPGSSGPSGDEG----QPGEPGPPGEKGEAGDEGNP 415
           G P  G  G  GEKG  G  G  G+PG  GP GD G    QPG+PG PG  G  GD G P
Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLP 680

Query: 416 GPDGAPGER-----------------GGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREG 458
           G  G PG+                  G PG  GP+G PG  GP G PG  G  G +G  G
Sbjct: 681 GDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPG 740

Query: 459 PVGVPGDPGE-----AGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGD---PGLMGERGE 510
           P G PG  GE      GP GP G  G +G  G +G RG PGP GPPG     GL G +G+
Sbjct: 741 PPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGD 800

Query: 511 DGPAGN-GTEGFPGFP--GYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDI-APRG 566
            GP G  G  G PG P  G  G  G PGI G  G PGL G  GE GDPG    D+  P G
Sbjct: 801 VGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPG 860

Query: 567 VKGAKGYRGPEGPQGPPGHQGPPG 590
            +G+ G  G  GP GPPG  G PG
Sbjct: 861 ERGSPGIPGAPGPIGPPGSPGLPG 884



 Score =  266 bits (679), Expect = 1e-70
 Identities = 178/436 (40%), Positives = 208/436 (47%), Gaps = 108/436 (24%)

Query: 257 GPPGLRGDPG---FEGERGKPGLPGEKGEAGDPGRPGDLGPVG--YQGMKGEKGSRGEKG 311
           GPPG++G PG     G  G PG PG  G  G PG PG  G +G  +QG KGEKG +G +G
Sbjct: 177 GPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQG 236

Query: 312 SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP----KGDPGAF 367
             GP G   E+ KR ID    V+ + G  GLPG +G PG  GI+GPPGP    KG+ G  
Sbjct: 237 PPGPPGQISEQ-KRPID----VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQ 291

Query: 368 GLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA------- 420
           G  G++G+PG DGE G+PG  G  GD G PGEPG  GEKG+ GD G PGP G        
Sbjct: 292 GEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGT 351

Query: 421 ------------------PGERGGPGERGPRGTPGTRG--------PRGDPGEAGPQGDQ 454
                              GERG PG +GP G PG  G        P G PGE G +GD+
Sbjct: 352 GITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDE 411

Query: 455 GREG-----PVGVPGDPGEAGPIGPKGYRGDEGPPGSEGAR-GAPGPAGPPGDPGLMGER 508
           G  G     P G+ G PG  G  GP G  G   PP  E    G PGP G PGD GL GE+
Sbjct: 412 GPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQ 471

Query: 509 GEDGPAGN--------------------------GTEGFP---------------GFPGY 527
           G  G  G+                          G+ GFP               G PG 
Sbjct: 472 GVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI 531

Query: 528 PGNRGAPGINGTKG-------YPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQ 580
           PG  GAPG  G+KG       +PG+KGD+GE G PG       P G  G  G  G  GP+
Sbjct: 532 PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLP-GTPGQDGLPGLPGPK 590

Query: 581 GPP------GHQGPPG 590
           G P      G +GPPG
Sbjct: 591 GEPGGITFKGERGPPG 606



 Score =  265 bits (676), Expect = 2e-70
 Identities = 165/364 (45%), Positives = 186/364 (51%), Gaps = 39/364 (10%)

Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG--S 312
           A G PGL G P   G+ G PGLPG KGE G     G+ GP G  G+ G  G+ G  G   
Sbjct: 568 APGLPGLPGTP---GQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG 624

Query: 313 RGPKGYKGEKGKRGI------DGVDGVKGEMG----YPGLPGCKGSPGFD---GIQGPPG 359
            GP G  GEKG +G+       G+ G KG+ G     PG PG  G+PG D   G+ G PG
Sbjct: 625 FGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPG 684

Query: 360 PKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDG 419
             G PG  G+ G KGEPG  G  G PG  GP G  G PG PG PG  G  G EG PGP G
Sbjct: 685 LPGQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPG 743

Query: 420 APGERGG-----PGERGPRGTPGTR---GPRGDPGEAGPQGDQGREGPVGVPGDPGEAGP 471
            PG +G      PG  GP G PG +   GP+GD G  GP G  GR G  G+PG  G+ GP
Sbjct: 744 FPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGP 803

Query: 472 IGPKGYRGDEGPP-----GSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPG 526
            G  G  G  G P     G  G  G PGP G PG  G+ GE+G+ GP G    G PG  G
Sbjct: 804 NGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERG 863

Query: 527 YPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQ 586
            PG  GAPG  G  G PGL G  G +G PG        +G  G  G  GP GP G PG  
Sbjct: 864 SPGIPGAPGPIGPPGSPGLPGKAGASGFPG-------TKGEMGMMGPPGPPGPLGIPGRS 916

Query: 587 GPPG 590
           G PG
Sbjct: 917 GVPG 920



 Score =  261 bits (666), Expect = 3e-69
 Identities = 176/457 (38%), Positives = 203/457 (44%), Gaps = 124/457 (27%)

Query: 257 GPPGLRGDPG-------------FEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGE 303
           GPPG+RG PG               G+RGKPG  GE G+ G PG PGD G  G  G  GE
Sbjct: 270 GPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGE 329

Query: 304 KGSRGEKGSRGPKGYK----------GEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDG 353
           KG +G+ G  GP G            GEKG  G+ G+ G KGE G+PG+ G  G PG  G
Sbjct: 330 KGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG 389

Query: 354 --IQGPPGPKGDPGAFGLKGEKGEPGA--------DGEAGRPGSSGPSGDEG-------- 395
             + GPPGP G PG  G KG++G PG         DG+ G PG  GP G  G        
Sbjct: 390 AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449

Query: 396 --QPGEPGPPG---------EKGEAGDEGN-------------------PGPDGAPGERG 425
             +PG PGPPG         E+G  GD+G+                   PG  G PG  G
Sbjct: 450 ICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLG 509

Query: 426 GPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGD----------PGEAGPIGPK 475
            PG++G +G  G  GP+G PG  G  G  G  G  G PGD           GE G  G  
Sbjct: 510 FPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAP 569

Query: 476 GYRGDEGPPGSEGARGAPGPAG------------PPGDPGLMGERGEDGPAG-------- 515
           G  G  G PG +G  G PGP G            PPG+PGL G  G  GP G        
Sbjct: 570 GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG 629

Query: 516 -------NGTEGFPGFPGYPGNRGAPGIN-------GTKGYPGLKGDEGEAGDPGDDNND 561
                   G  G PG PG PG +G PG         G  G PG  GD G  GDPG     
Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689

Query: 562 IAPRGVKGAK--------GYRGPEGPQGPPGHQGPPG 590
             P G+ G+K        G  GP GP+G PG  GPPG
Sbjct: 690 GLP-GIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPG 725



 Score =  221 bits (563), Expect = 3e-57
 Identities = 129/306 (42%), Positives = 149/306 (48%), Gaps = 44/306 (14%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPG--DLGPVGYQGMKGEKGSRGEKGSRG 314
            G PG  G PG +G+ G+ G+PG  G+ G+PG+PG  + GP G  G+ G+KG  G  G  G
Sbjct: 1155 GHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPG 1214

Query: 315  PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCK--------------GSPGFDGIQGPPGP 360
              G  G KG+ G  G  GV+G  G PG PG                G PGF G+ GP GP
Sbjct: 1215 NPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGP 1274

Query: 361  KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA 420
             G PG  G+KGEKG PG  G  G PG  G  G  G  G PG PG  G  GD G PG  G 
Sbjct: 1275 PGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGF 1334

Query: 421  PGERGG---PGERGPRGTPGTRGPRGDPGEAGPQGD----QGREGPVGVPGDPGEAG--- 470
            PG +G    PG  GP G PG  GP G PG  GP G     +G  GP G+PG PG  G   
Sbjct: 1335 PGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPG 1394

Query: 471  PIGPKGYRGDEGPPGSEGARGAPG------------------PAGPPGDPGLMGERGEDG 512
            P GP+G  G  GPPG  G  G PG                    G  G PG  G +G  G
Sbjct: 1395 PQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPG 1454

Query: 513  PAGNGT 518
            P G  +
Sbjct: 1455 PPGTSS 1460



 Score =  220 bits (561), Expect = 5e-57
 Identities = 138/348 (39%), Positives = 156/348 (44%), Gaps = 86/348 (24%)

Query: 329 GVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD------------------------- 363
           G+ G KGE G+PGL G  G PGF G +GPPGP+G                          
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP 101

Query: 364 --------------------PGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGP- 402
                               PG  G KGE+G PG+ G  G  G  GP G  G  GEPG  
Sbjct: 102 GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSI 161

Query: 403 -----PGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGR- 456
                PG KG  G  G PG  G PG  G PG  GP G PG  GP G PG  GP+G+ G  
Sbjct: 162 IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLN 221

Query: 457 -EGPVGVPGDPGEAGPIGPKG-------------YRGDEGPPGSEGARGAPGPAGPPGDP 502
            +GP G  G+ G  GP GP G              +GD+G PG  G  G PG  GPPG P
Sbjct: 222 FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPP 281

Query: 503 -GLMGERGEDG-------PAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGD 554
            G  GE+GE G       P  +G  G PG PG PG+ G PG  G  G  G KGD G  G 
Sbjct: 282 GGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGP 341

Query: 555 PG------------DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           PG             +  +I   G+ G KG RG  G QGPPG  GPPG
Sbjct: 342 PGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG 389



 Score =  172 bits (436), Expect = 1e-42
 Identities = 101/233 (43%), Positives = 126/233 (54%), Gaps = 21/233 (9%)

Query: 256  RGPPGLRGDPG--FEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQG---MKGEKGSRGEK 310
            +GPPG  G PG   EG +G PG  G  G  G  G PG  GP G  G   +KGEKG+ G+ 
Sbjct: 1234 QGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQP 1293

Query: 311  GSRGPKGYKGEKGKRGIDG------VDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDP 364
            G  G  G KG++G  G+ G      ++G+KG+ G PG+PG  G  G  G+ G  GP+G+P
Sbjct: 1294 GLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEP 1353

Query: 365  GAFGLKGEKGEPGADGEA-GRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGE 423
            G  G  G  G PG  G++    G +GP G  GQPG  G PG +   G +G PGP G PG+
Sbjct: 1354 GLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQ---GPQGLPGPTGPPGD 1410

Query: 424  RGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKG 476
               PG  G  G  G  G +GDPG  G  G +G +GP   PG  G  GP GP G
Sbjct: 1411 ---PGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGP---PGPDGLQGPPGPPG 1457



 Score =  161 bits (408), Expect = 3e-39
 Identities = 103/251 (41%), Positives = 115/251 (45%), Gaps = 36/251 (14%)

Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436
           G   EA       P       G  G  GE+G  G EG+PG  G PG  G PG RG +G  
Sbjct: 21  GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80

Query: 437 GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY------RGDEGPPGSEGAR 490
           G  GP G  G  GP G  G  G  G+PG PG  G  GP+G       +G+ G PGS G  
Sbjct: 81  GIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP 140

Query: 491 GAPGPAGPPGDPGLMGERGE------DGPAGN-GTEGFPGFPGYPGNRGAPGINGTKGYP 543
           G  GP GPPG PG+ GE G        GP GN G  G PG  G PG  G PG  G  G P
Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPP 200

Query: 544 GLKGDEGEAGDPGDDN----NDIAPRGVKGAKGYRGPEGP-------------------Q 580
           GL G  G  G PG       N   P+G KG +G +GP GP                   Q
Sbjct: 201 GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQ 260

Query: 581 GPPGHQGPPGP 591
           G PG +GPPGP
Sbjct: 261 GLPGDRGPPGP 271



 Score =  131 bits (330), Expect = 3e-30
 Identities = 82/190 (43%), Positives = 96/190 (50%), Gaps = 37/190 (19%)

Query: 257  GPPGLRGDPGFEGERGKPG------LPGEKGEAGDPGRPGDLGPVGYQGMKGE------- 303
            GPPGL G+ G +GE+G PG      LPG KG+ G PG  G+ G  G  GMKG+       
Sbjct: 1273 GPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVP 1332

Query: 304  -----KGSRGEKGSRGPKGYKGEKGKRGIDGVDG-------VKGEMGYPGLPG---CKGS 348
                 KG  G  GS GP+G  G  G  G  G+ G       +KG+ G PG+PG    KG 
Sbjct: 1333 GFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGL 1392

Query: 349  PGFDGIQG---PPGPKGDPGAFGLKG------EKGEPGADGEAGRPGSSGPSGDEGQPGE 399
            PG  G QG   P GP GDPG  GL G       KG+PG  G+ G  G  GP G +G  G 
Sbjct: 1393 PGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGP 1452

Query: 400  PGPPGEKGEA 409
            PGPPG    A
Sbjct: 1453 PGPPGTSSVA 1462



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 27/62 (43%), Positives = 29/62 (46%)

Query: 253  QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312
            Q  +G PG  G PG  G  G PG  G  G  GDPG PG  G  G  G  G  G +G  G 
Sbjct: 1396 QGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGP 1455

Query: 313  RG 314
             G
Sbjct: 1456 PG 1457



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 30/75 (40%), Positives = 36/75 (48%), Gaps = 3/75 (4%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            +G PG +G  G  G  G PG PG  G    PG  G  G  G  G+ G+ G+RG  G  GP
Sbjct: 1390 KGLPGPQGPQGLPGPTGPPGDPGRNGL---PGFDGAGGRKGDPGLPGQPGTRGLDGPPGP 1446

Query: 316  KGYKGEKGKRGIDGV 330
             G +G  G  G   V
Sbjct: 1447 DGLQGPPGPPGTSSV 1461


>gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]
          Length = 1714

 Score =  297 bits (761), Expect = 3e-80
 Identities = 168/375 (44%), Positives = 202/375 (53%), Gaps = 40/375 (10%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            G PG  G  G  G+RG+PG  G+KG+ G  G  G  GP G  G  G KG+RG +G+ G  
Sbjct: 1098 GLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHL 1157

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDG----IQGPPGPKGDPGAFGLKGE 372
            G  G  G+ GI G  G +G+ G  GLPG KG  G+ G    + GPPGP+G+PG  G +GE
Sbjct: 1158 GLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGE 1217

Query: 373  KGEPGADGEAGR---PGSSGPSGDEGQPGEPGPPGE---KGEAGDEGNPGPDGAPGERGG 426
            +GEPGA+G  G    PG  G +G +G PGEPG  GE   KGE G EGN G  GAPG  G 
Sbjct: 1218 RGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGK 1277

Query: 427  PG---------ERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY 477
            PG          +G +G  G  G  G+PG+ GP G QG  G  G PG  G AG  GP G 
Sbjct: 1278 PGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGV 1337

Query: 478  RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFPGFPGYPGNRGAPGI 536
            +G  G PGS G +G  G  G PG PG+ G+RG  G  G+ G  G PG  G PG  G  G+
Sbjct: 1338 KGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGL 1397

Query: 537  NGTKGYPGLKGDEGEAG-----------------DPGDDNNDIAPRG---VKGAKGYRGP 576
             G +G+PG KG EG+AG                  P      I P G    +G KG+RG 
Sbjct: 1398 TGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGE 1457

Query: 577  EGPQGPPGHQGPPGP 591
             GPQGP G  GPPGP
Sbjct: 1458 TGPQGPRGQPGPPGP 1472



 Score =  278 bits (712), Expect = 1e-74
 Identities = 159/350 (45%), Positives = 189/350 (54%), Gaps = 17/350 (4%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMK------GEKGSRGEK 310
           GPPG  G PG  G+RG  G+PG  G  G PG PG  GP G  G        GEKG +G  
Sbjct: 498 GPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLS 557

Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA---- 366
           G  GP G +G+KG +G  G+ G+ GE G PG  G  GSPG+ G QG  GP+G+PG     
Sbjct: 558 GLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQ 617

Query: 367 --FGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGER 424
              G  GE G+ G +GE G PG  G  G +G+ G PG  G++G AG +G+PG  G  G  
Sbjct: 618 GFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPP 677

Query: 425 GGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGP- 483
           G PG RG  G  G  GP G PG  G  G++G  G  G  G+ G AG +G  GY GD+G  
Sbjct: 678 GFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAV 737

Query: 484 --PGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGNRGAPGINGTK 540
             PG  G RG  GP+G  GDPGL G  G  GP G  G  G PG  G  G +G  G  G  
Sbjct: 738 GLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPP 797

Query: 541 GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           G PGLKG +GE G P     ++ PRG  G KGY G  GP+G  G  G  G
Sbjct: 798 GPPGLKGTQGEEG-PIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQG 846



 Score =  273 bits (697), Expect = 8e-73
 Identities = 160/359 (44%), Positives = 190/359 (52%), Gaps = 27/359 (7%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKG------EAGDPGRPGDLGPVGYQGMKGEKGSRGEK 310
           GPPG++GD G +G  G PGLPGE+G        G PG PG  G  G +G  G KG++G  
Sbjct: 561 GPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFI 620

Query: 311 GSRGPKGYKGEKGKRGIDGV---DGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAF 367
           GS G  G  G +G+RGI G+    G KG  G+PG  G +G  G DG  G  G  G PG  
Sbjct: 621 GSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFP 680

Query: 368 GLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGP 427
           GL+G  G  G  G AG PG  G SG++G PG  G  GE+G AG+ G PG    PG++G  
Sbjct: 681 GLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPG---YPGDKGAV 737

Query: 428 GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGD---PGEAGPIGPKGYRGDEGPP 484
           G  GP G  G  GP G  G+ G QG  G  GP G PGD   PG+ GP GPKG  G+ GPP
Sbjct: 738 GLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPP 797

Query: 485 GSEGARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFPGYPGNRGAPGINGTK 540
           G  G +G  G  GP G  G +G RG+ G  G     G EG  G  G  GN G  G  G  
Sbjct: 798 GPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPV 857

Query: 541 GYPGLKGDEGEAGDPGDDNN--DIAPRGVKGAKGYRGPEGPQGP------PGHQGPPGP 591
           G PG  G  G  G+ G+  +   + P+G KG  GY GP G  GP      PGH G  GP
Sbjct: 858 GLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGP 916



 Score =  272 bits (696), Expect = 1e-72
 Identities = 163/371 (43%), Positives = 191/371 (51%), Gaps = 39/371 (10%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGE---------AGDPGRPGDLGPVGYQGMKGEKGS 306
            RGP GL G PG  G  G PG PG +G          AG PG  G  G  G  G+KG+KG 
Sbjct: 659  RGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGE 718

Query: 307  RGEKGSRGPKGYKGEKGKRGIDGVDGVKG------EMGYPGLPGCKGSPGFDGI------ 354
            +G  G  G  GY G+KG  G+ G  G++G      + G PGL G  G PG +G       
Sbjct: 719  QGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGI 778

Query: 355  ---QGPPGPKG------DPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGE 405
                GP GPKG       PG  GLKG +GE G  G  G  G  G  G +G  GEPGP G 
Sbjct: 779  PGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGL 838

Query: 406  KGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGD 465
            KGE GD+GN G  G  G  G PGE G  G+ G +G RG PG  GPQG++G  G  G PG 
Sbjct: 839  KGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGV 898

Query: 466  PGEAGPIGPKGYRGDEGPPGSE---GARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGF 521
            PG  GP+G  G+ G  GPPGS+   G RG+ GP G  G+ G+ G +GE G  G  G  G 
Sbjct: 899  PGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGL 958

Query: 522  PGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPG--DDNNDIAPRGVKGAKGYRGPEGP 579
             G  G PG RG  G  G +G PG  GD G  G+PG      D+ P    G  G  GP G 
Sbjct: 959  IGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGP---PGEMGMEGPPGT 1015

Query: 580  QGPPGHQGPPG 590
            +G  G QG PG
Sbjct: 1016 EGESGLQGEPG 1026



 Score =  268 bits (686), Expect = 1e-71
 Identities = 156/353 (44%), Positives = 187/353 (52%), Gaps = 24/353 (6%)

Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
           RG PG+RG  GF+G +G PG  G++G AG  G PG +G  G  G  G +GS G  G  GP
Sbjct: 635 RGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGP 694

Query: 316 KGYKGEKGKRGIDGVDGVKG---------EMGYPGLPGCKGS------PGFDGIQGPPGP 360
            G  G  G  G  G+ G+KG         E+G PG PG KG+      PG  G  GP G 
Sbjct: 695 AGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQ 754

Query: 361 KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDE---GQPGEPGPPGEKGEAGDEGNPGP 417
            GDPG  G  G  G  G  G+ G PG +GP G +   G  G PGPPG KG  G+EG  G 
Sbjct: 755 TGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGA 814

Query: 418 DGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY 477
            G  G RG PG++G  G PG  G +G+ G+ G  G  G  GPVG+PG+ G  G IG KG 
Sbjct: 815 FGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGE 874

Query: 478 RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGIN 537
           RG  GP G +G +G  G  GPPG PG +G  G  G    G  G PG  G  G RG+ G +
Sbjct: 875 RGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHV--GARGPPGSQGPKGQRGSRGPD 932

Query: 538 GTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           G  G  G++G +GE GD G       P G+ G  G  G  G QG PG QG PG
Sbjct: 933 GLLGEQGIQGAKGEKGDQGKR----GPHGLIGKTGNPGERGFQGKPGLQGLPG 981



 Score =  267 bits (682), Expect = 4e-71
 Identities = 161/370 (43%), Positives = 195/370 (52%), Gaps = 37/370 (10%)

Query: 255  ARGPPGLRGDPGFEGERGKPGLPGE------KGEAGDPGRPGDLGPVGYQGMKGEKGSRG 308
            ARGPPG +G  G  G RG  GL GE      KGE GD G+ G  G +G  G  GE+G +G
Sbjct: 913  ARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQG 972

Query: 309  EKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFD---GIQGPPGPKGDPG 365
            + G +G  G  G++G  G  G+ G++G++G PG  G +G PG +   G+QG PG KGD G
Sbjct: 973  KPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVG 1032

Query: 366  AFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGP---PGEKGEAGDEGNPGPDGAPG 422
              G  G  GEPG  GE G PG  G  G +G  G PG    PGE GE G+ G PG  G  G
Sbjct: 1033 TAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLG 1092

Query: 423  ERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYR---- 478
              G  G  GP G  G  G RG PG+ G +G  G  G VG  G PG+ G  GPKG R    
Sbjct: 1093 RSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRG 1152

Query: 479  -----------GDEGPPGSEGARGAPGPAGPPGDPGLMGERGED----GPAGNGTEGFPG 523
                       G+ G PG  G +G PGP+G PG  G  G  GED    GP   G  G PG
Sbjct: 1153 AVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPP--GPRGEPG 1210

Query: 524  FPGYPGNRGAPGINGTKGY---PGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQ 580
              G  G RG PG  G KG+   PGL+G  G+ G PG+   D   +G+KG +G  G +G +
Sbjct: 1211 PVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEP-GDQGEQGLKGERGSEGNKGKK 1269

Query: 581  GPPGHQGPPG 590
            G PG  G PG
Sbjct: 1270 GAPGPSGKPG 1279



 Score =  266 bits (680), Expect = 7e-71
 Identities = 161/371 (43%), Positives = 194/371 (52%), Gaps = 40/371 (10%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRG------EK 310
            GP G +G+ G  G  G PG+PG  G  G PG  G  GP G QG KG++GSRG      E+
Sbjct: 879  GPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQ 938

Query: 311  GSRGPKGYKGEKGKRGIDGV---DGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAF 367
            G +G KG KG++GKRG  G+    G  GE G+ G PG +G PG  G +G PG   +PG  
Sbjct: 939  GIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPG---EPGLR 995

Query: 368  GLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPG---PDGAPGER 424
            GL+G+ G PG  G  G PG+ G SG +G+PG  G  G  G  G  G PG     GAPGE 
Sbjct: 996  GLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEE 1055

Query: 425  GGPGERGPRGTPGTRGPRGDPGEAGP------------QGDQGREGPVGVPGDPGEAGPI 472
            G  G+ G +G PG RG  G+ GE G              G  G  GP G+ G PG+ G  
Sbjct: 1056 GLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRP 1115

Query: 473  GPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGY---- 527
            G KG +G  GP G  G+RG PG  G  G  G  G RG  G  G  G +G PG PGY    
Sbjct: 1116 GKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQ 1175

Query: 528  --PGNRGAPGINGTKGYPG----LKGDEGEAGDPG--DDNNDIAPRGVKGAKGYRGPEGP 579
              PG  G PG  G KGYPG    + G  G  G+PG   D  +    G +G KG+ G  G 
Sbjct: 1176 GQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGL 1235

Query: 580  QGPPGHQGPPG 590
            +G  G QGPPG
Sbjct: 1236 RGATGQQGPPG 1246



 Score =  265 bits (676), Expect = 2e-70
 Identities = 162/395 (41%), Positives = 198/395 (50%), Gaps = 71/395 (17%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGE------KGSRGEK 310
           G PG +G PGF G  G PG PG +G AG  G PG  G  G+ G  GE      +G RG  
Sbjct: 579 GLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIP 638

Query: 311 GSRGPKGYKG---------EKGKRGIDGVDGVKGEMGYPGLPGCKGSPGF------DGIQ 355
           G RG KG+KG         ++G  G+DG  G+ G  G PG PG +GS G        GI 
Sbjct: 639 GIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIP 698

Query: 356 GPPGPKGDPGAFGLKGEKGEPGADGEAGRPG------------------SSGPSGDEGQP 397
           GP G  G+ G  G+KG+KGE G  GE G PG                   SGPSG  G P
Sbjct: 699 GPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDP 758

Query: 398 GEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGRE 457
           G  GP          G PGP+G PG+ G PG+ GP G  G  G RG PG  G +G QG E
Sbjct: 759 GLQGP---------SGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEE 809

Query: 458 GPVGV---------PGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGL---- 504
           GP+G          PG  G AG  GP+G +G+ G  G+ G  G  GP G PG+ G+    
Sbjct: 810 GPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSI 869

Query: 505 --MGERGEDGPAG----NGTEGFPGFPGYP---GNRGAPGINGTKGYPGLKGDEGEAGDP 555
              GERG  GP G     G  G+PG PG P   G  G PG  G +G PG +G +G+ G  
Sbjct: 870 GEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSR 929

Query: 556 GDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           G D   +  +G++GAKG +G +G +GP G  G  G
Sbjct: 930 GPDGL-LGEQGIQGAKGEKGDQGKRGPHGLIGKTG 963



 Score =  264 bits (674), Expect = 4e-70
 Identities = 159/379 (41%), Positives = 186/379 (49%), Gaps = 48/379 (12%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            GPPG+RG  G  G+ G PGL G  G  G  G PGD+G  G  G +G KG  G +G  GP 
Sbjct: 741  GPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPP 800

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEP 376
            G KG +G+ G  G  G  G  G PG  G  G PG +G++G  G   D G  G  GE G  
Sbjct: 801  GLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVG---DQGNIGKIGETGPV 857

Query: 377  GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436
            G  GE G  GS G  G+ G PG  GP GEKG  G  G PG  G  G  G PG  G RG P
Sbjct: 858  GLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPP 917

Query: 437  GTRGPRGDPGEAGPQ---GDQGREGPVGVPGDPGEAGP------IGPKGYRGDEGPPGSE 487
            G++GP+G  G  GP    G+QG +G  G  GD G+ GP       G  G RG +G PG +
Sbjct: 918  GSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQ 977

Query: 488  GARGAPGPAGPPGDPGLMGERGEDGPAGN-------GTEGFPGFPGYPGNR--------- 531
            G  G+ G  G PG+PGL G +G+ GP G        GTEG  G  G PG +         
Sbjct: 978  GLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSV 1037

Query: 532  ------------GAPGINGTKGYPGLKGDEGEAGDPGDDNND--------IAPRGVKGAK 571
                        GAPG  G +G  GLKG  G  G PG+D           I P G  G  
Sbjct: 1038 GGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQT 1097

Query: 572  GYRGPEGPQGPPGHQGPPG 590
            G  GPEG  G PG +G PG
Sbjct: 1098 GLPGPEGIVGIPGQRGRPG 1116



 Score =  263 bits (671), Expect = 8e-70
 Identities = 163/383 (42%), Positives = 193/383 (50%), Gaps = 48/383 (12%)

Query: 257  GPPGLRGDPGFEG------ERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRG-- 308
            GPPGL+G  G EG      E G  G PG+KG AG+PG  G  G VG QG  G+ G  G  
Sbjct: 798  GPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPV 857

Query: 309  ----EKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDP 364
                E G  G  G KGE+G  G  G  G KG MGYPG PG  G  G  G+ G  G +G P
Sbjct: 858  GLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPP 917

Query: 365  GAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGER 424
            G+ G KG++G  G DG  G  G  G  G++G  G+ GP G  G+ G+ G  G  G PG +
Sbjct: 918  GSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQ 977

Query: 425  GGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGP------VGVPGDPGEAGPI------ 472
            G PG  G RG PG  G RG  G+ GP G+ G EGP       G+ G+PG  G +      
Sbjct: 978  GLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSV 1037

Query: 473  ---GPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFP 525
               G  G RG+ G PG EG +G  G  G PG  GL GE GE G  G     G  G  G  
Sbjct: 1038 GGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQT 1097

Query: 526  GYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAP-----------RGVKGAKGYR 574
            G PG  G  GI G +G PG KGD+G+ G  G+  +   P           RG +GA G+ 
Sbjct: 1098 GLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHL 1157

Query: 575  GPEGPQGPP------GHQGPPGP 591
            G  GP G P      GHQG PGP
Sbjct: 1158 GLMGPDGEPGIPGYRGHQGQPGP 1180



 Score =  258 bits (660), Expect = 2e-68
 Identities = 172/417 (41%), Positives = 200/417 (47%), Gaps = 85/417 (20%)

Query: 253  QPARGPPGL---RGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQG---MKGEKGS 306
            Q  RGP GL    G+PG  G +GKPGL G  G  GD G PG+ G  G QG     GE G 
Sbjct: 950  QGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGM 1009

Query: 307  RGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366
             G  G+ G  G +GE G +G  G  G  G  G PGL G  G+PG +G+QG  G KG PG 
Sbjct: 1010 EGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGG 1069

Query: 367  FGLKGEKGEPGADGEAGR---PGSSGPSGDEGQPGEPGP------PGEK---GEAGDEGN 414
             GL      PG DGE G    PG  GP G  GQ G PGP      PG++   G+ GD+G 
Sbjct: 1070 RGL------PGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQ 1123

Query: 415  PGPDGAPGERGGP---GERGPRGTPGTR---------GPRGDPGEAGPQGDQGREGPVGV 462
             GP G  G RG P   G+ GP+G  GTR         GP G+PG  G +G QG+ GP G+
Sbjct: 1124 IGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGL 1183

Query: 463  PGDPGEAG-------PIGPKGYRGDEGPPGSEGARGAP------------------GPAG 497
            PG  GE G        +GP G RG+ GP G +G RG P                  G  G
Sbjct: 1184 PGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQG 1243

Query: 498  PPGDP------GLMGERGEDGPAGN----GTEGFPGFPGYPGNRGAPGINGTKGYPGLKG 547
            PPG+P      GL GERG +G  G     G  G PG PG  G  G  GI G  G  G+ G
Sbjct: 1244 PPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISG 1303

Query: 548  DEGEAGDPGDDN--------------NDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
            + G+ G PG                     P GVKG+ G  G  G QGP G QG PG
Sbjct: 1304 NPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPG 1360



 Score =  256 bits (653), Expect = 1e-67
 Identities = 151/346 (43%), Positives = 180/346 (52%), Gaps = 13/346 (3%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            RGPPG  G  G +GE G  G  GE G  G PG+ G  G  G +G+KGE G +G  G  G 
Sbjct: 794  RGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGE 853

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375
             G  G  G+ G+ G  G KGE G PG  G +G  G  G  GPPG  G  G  GL G  G 
Sbjct: 854  TGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGA 913

Query: 376  PGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGT 435
             G  G  G  G  G  G +G  GE G  G KGE GD+G  GP G  G+ G PGERG +G 
Sbjct: 914  RGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGK 973

Query: 436  PGTRGPRGDPGEAGPQGD---QGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGA 492
            PG +G  G  G+ G  G+   +G +G VG PG+ G  GP G +G  G +G PG++G  G 
Sbjct: 974  PGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGT 1033

Query: 493  PGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLK------ 546
             G  G  G+PGL GE G   P   G +G  G  G PG RG PG +G KG  GL       
Sbjct: 1034 AGSVGGTGEPGLRGEPG--APGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPL 1091

Query: 547  GDEGEAGDPGDDNNDIAP--RGVKGAKGYRGPEGPQGPPGHQGPPG 590
            G  G+ G PG +     P  RG  G KG +G  GP G  G +GPPG
Sbjct: 1092 GRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPG 1137



 Score =  244 bits (623), Expect = 3e-64
 Identities = 137/287 (47%), Positives = 158/287 (55%), Gaps = 8/287 (2%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            GPPG RG+PG  G++G+ G PG +G  G  G PG  G  G QG  GE G +GE+G +G +
Sbjct: 1201 GPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGER 1260

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGF---DGIQGPPGPKGDPGAFGLKGEK 373
            G +G KGK+G  G  G  G  G  GL G KG  G+   DGI G PG  G PG  GL G +
Sbjct: 1261 GSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIR 1320

Query: 374  GEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPR 433
            G PG  G AG PG  G  G  G PG PG  G KGE G  G PG  G  G RG  G++GP 
Sbjct: 1321 GGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPC 1380

Query: 434  GTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGE---AGPIGPKGYRGDEGPPGSEGAR 490
            G PG +G  G+ G  G  G QG  GP G  GD G    +GP GP G+RG+ GP G EG  
Sbjct: 1381 GDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGII 1440

Query: 491  GAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGIN 537
            G  G  GP G+ G  GE G  GP   G  G PG PG PG R    IN
Sbjct: 1441 GPTGRTGPRGEKGFRGETGPQGP--RGQPGPPGPPGAPGPRKQMDIN 1485



 Score =  239 bits (611), Expect = 7e-63
 Identities = 145/356 (40%), Positives = 176/356 (49%), Gaps = 43/356 (12%)

Query: 255  ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGS-RGEKGSR 313
            ARG  G  G  G  G  G+PG+PG +G  G PG  G  GP G +G  GE  +  G  G R
Sbjct: 1147 ARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPR 1206

Query: 314  GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGC---KGSPGFDGIQGPPGPKGDPGAFGLK 370
            G  G  G++G+RG  G +G KG +G PGL G    +G PG  G QG  G KG+ G+ G K
Sbjct: 1207 GEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNK 1266

Query: 371  GEKGEPGADGEAGRPGSSG------------PSGDEGQPGEPGPPGEKGEAGDEGNPGPD 418
            G+KG PG  G+ G PG  G              G  G PG+ GPPG++G  G  G PG  
Sbjct: 1267 GKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRT 1326

Query: 419  ---GAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475
               GAPG  G  G  G  G+PG +GP+G+ G  G  G QG+ G  G  GD G  G  G K
Sbjct: 1327 GLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLK 1386

Query: 476  GYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPG 535
            G  G+ G  G  G +G PGP GP GD G++G  G  GP            G+ GN G  G
Sbjct: 1387 GQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPI-----------GHRGNTGPLG 1435

Query: 536  INGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
              G  G  G  G  GE             +G +G  G +GP G  GPPG  G PGP
Sbjct: 1436 REGIIGPTGRTGPRGE-------------KGFRGETGPQGPRGQPGPPGPPGAPGP 1478



 Score =  150 bits (380), Expect = 5e-36
 Identities = 87/209 (41%), Positives = 98/209 (46%), Gaps = 24/209 (11%)

Query: 255  ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG--- 311
            A GP G  G PG +G  G  G+ G  G  G  G PG +GP G QG+ G +G  G  G   
Sbjct: 1271 APGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAG 1330

Query: 312  SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKG 371
            + GP G KG  G  G  G+ G KGE G PG PG +G  G  G QG  GP GDPG  G  G
Sbjct: 1331 APGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPG 1390

Query: 372  EKGEPGADGEAGRPGSSGPSGDEG---------------------QPGEPGPPGEKGEAG 410
            E G  G  G  G PG  GP GD G                     + G  GP G  G  G
Sbjct: 1391 EYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRG 1450

Query: 411  DEGNPGPDGAPGERGGPGERGPRGTPGTR 439
            ++G  G  G  G RG PG  GP G PG R
Sbjct: 1451 EKGFRGETGPQGPRGQPGPPGPPGAPGPR 1479



 Score =  103 bits (257), Expect = 8e-22
 Identities = 61/155 (39%), Positives = 76/155 (49%), Gaps = 27/155 (17%)

Query: 253  QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312
            Q  +G  GL G PG +G+RG  G  G++G  GDPG  G  G  G QG+ G +G  G    
Sbjct: 1350 QGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGP--- 1406

Query: 313  RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372
                  KG +G  GI G+ G KG +G+ G  G  G  G  G  G  GP+G+      KG 
Sbjct: 1407 ------KGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGE------KGF 1454

Query: 373  KGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKG 407
            +GE            +GP G  GQPG PGPPG  G
Sbjct: 1455 RGE------------TGPQGPRGQPGPPGPPGAPG 1477



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 24/56 (42%), Positives = 27/56 (48%), Gaps = 7/56 (12%)

Query: 536 INGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
           + G KG  G  G  G AG PG       P G +G +G  GP G  G PG  GP GP
Sbjct: 487 LRGPKGDTGPPGPPGPAGIPG-------PSGKRGPRGIPGPHGNPGLPGLPGPKGP 535


>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
          Length = 680

 Score =  295 bits (754), Expect = 2e-79
 Identities = 183/433 (42%), Positives = 218/433 (50%), Gaps = 96/433 (22%)

Query: 253 QPARGPPGLRGDPGFEG--------ERGKPGLPGEKGEAGDPGRPGDLGPVGYQG----- 299
           +P  G PGL+G+PG  G        + G PGLPG+ GE G  G  GD+GP G  G     
Sbjct: 82  KPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPP 141

Query: 300 ------------MKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGY--PGLPGC 345
                       + G+ G +G  G+ GP+G+ GEKG  G+ G++G KGEMGY  PG PG 
Sbjct: 142 GPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGE 201

Query: 346 KGSPGFDGIQGPPGP--------KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDE--- 394
           +G PG  G  GP GP         G PG  G+KG++G PG  G  G PG  GP G+    
Sbjct: 202 RGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPE 261

Query: 395 --------GQPGEPGPPGEKGEAGDEGNPGPDGAP-----------GER------GGP-- 427
                   G PG+PG PG KG  G  G  GP G P           GER      GGP  
Sbjct: 262 GIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGA 321

Query: 428 -GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY---RGDEGP 483
            GE+GP G PG  G  G PG  GPQG +G  G  G+PG  GE GP GP GY   +G+ G 
Sbjct: 322 KGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGS 381

Query: 484 PGS------------EGARGAPGPAGPPGDPGLMGERGEDGPAG-NGTEGFPGFPGYPGN 530
           PGS            +G +G PG  GP GDPG+ G  G  GP G  G +G PG  G  G 
Sbjct: 382 PGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGP 441

Query: 531 RGAPGINGTK---------GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQ- 580
           RGAPGI GT+         G+PG KGD G  G PG     IA +G+ G  G  GP GP+ 
Sbjct: 442 RGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAG--IATKGLNGPTGPPGPPGPRG 499

Query: 581 --GPPGHQGPPGP 591
             G PG  GPPGP
Sbjct: 500 HSGEPGLPGPPGP 512



 Score =  260 bits (664), Expect = 5e-69
 Identities = 153/364 (42%), Positives = 182/364 (50%), Gaps = 53/364 (14%)

Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGD-----PGRPGDLGPVGYQG----------- 299
           +GP G  G  GF GE+G PG+PG  G+ G+     PGRPG+ G  G QG           
Sbjct: 161 QGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVG 220

Query: 300 ------------MKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVD--GVKGEMGYPGLPGC 345
                       +KG++G  GE G  GP G +G  G+RG +G+   G  G  G PG+PG 
Sbjct: 221 KRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGT 280

Query: 346 KGSPGFDGIQGPPGPKG--DPGAFGLKGEKGE------PGADGE------------AGRP 385
           KG PG  GI GPPGP G   PG  GLKGE+G       PGA GE             G P
Sbjct: 281 KGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPP 340

Query: 386 GSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRG---TPGTRGPR 442
           G+ GP G +G PG  G PG KGE G  G  G  GA GERG PG  G  G    PG  GP+
Sbjct: 341 GNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPK 400

Query: 443 GDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDP 502
           G+PG  GP+GD G  GP G+PG  G AG  G  G+ G+ GP G+ G  G  GP GPPG P
Sbjct: 401 GNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIP 460

Query: 503 GLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDI 562
           G  G +G+ G  G          G  G  G PG  G +G+ G  G  G  G PG     +
Sbjct: 461 GFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAV 520

Query: 563 APRG 566
            P G
Sbjct: 521 MPEG 524



 Score =  241 bits (616), Expect = 2e-63
 Identities = 152/348 (43%), Positives = 175/348 (50%), Gaps = 32/348 (9%)

Query: 271 RGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGV 330
           RG+ G PG  G AG  G PG  GP G  G  G  G +GE G  GP G     GK G+ G+
Sbjct: 56  RGEQGTPGPPGPAGPRGHPGPSGPPGKPGY-GSPGLQGEPGLPGPPG-PSAVGKPGVPGL 113

Query: 331 DGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGP 390
            G  GE G  G  G  G  G  G +GPPGP G PG  G+    G+PG  G  G PG  G 
Sbjct: 114 PGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGIS-VPGKPGQQGPTGAPGPRGF 172

Query: 391 SGDEGQPGEPGPPGEKGEAG--DEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEA 448
            G++G PG PG  G+KGE G    G PG  G PG +G  G  GP G  G RG  G PG+ 
Sbjct: 173 PGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGV-GKRGENGVPGQP 231

Query: 449 GPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGA------------RGAPGPA 496
           G +GD+G  G +G  G PG  GP G +G  G  G PG+ GA             GAPG A
Sbjct: 232 GIKGDRGFPGEMGPIGPPGPQGPPGERGPEGI-GKPGAAGAPGQPGIPGTKGLPGAPGIA 290

Query: 497 GPP-----GDPGLMGERGEDGPAG-------NGTEGFPGFPGYPGNRGAPGINGTKGYPG 544
           GPP     G PGL G +GE GPAG        G +G  G PG PG  G PG  G +G  G
Sbjct: 291 GPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKG 350

Query: 545 LKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPD 592
           + G  G  G P  +     P G  GAKG RG  G  G PG+ G PG D
Sbjct: 351 IPGSHGLPG-PKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLD 397



 Score =  233 bits (594), Expect = 7e-61
 Identities = 157/423 (37%), Positives = 181/423 (42%), Gaps = 131/423 (30%)

Query: 300 MKGEKGSRGEKGSRGPKGYKGEK----------------------------GKRGIDGVD 331
           ++GE+G+ G  G  GP+G+ G                              GK G+ G+ 
Sbjct: 55  VRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLP 114

Query: 332 ---------GVKGEMGYPGLPGCKGSPGFDGIQGP-----------------------PG 359
                    G KG++G  GLPG +G PG  GI GP                       PG
Sbjct: 115 GKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPG 174

Query: 360 PKGDPGAFGLKGEKGE-----PGADGEAGRPGSSGPSGDEGQP--------GEPGPPGEK 406
            KG PG  G+ G+KGE     PG  GE G PG  GP+G  G P        G PG PG K
Sbjct: 175 EKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIK 234

Query: 407 GEAGDEGNPGPDGAPGERGGPGERGPR--------------GTPGTRGPRGDPGEAGPQG 452
           G+ G  G  GP G PG +G PGERGP               G PGT+G  G PG AGP G
Sbjct: 235 GDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPG 294

Query: 453 D-----------QGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGD 501
                       +G  GP G+PG PG  G  GP G  G  G  G  G  G  GP G PG 
Sbjct: 295 PPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGS 354

Query: 502 PGLMGERGEDGPAG-------NGTEGFPGFPGYPGNRGAPGINGTKGYPGL---KGDEGE 551
            GL G +GE GPAG        G  G PG  G PG  G PG++G KG PGL   KGD G 
Sbjct: 355 HGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGV 414

Query: 552 AGDPG--------------DDNNDIAPRGVKGAKGYRGPEGP---------QGPPGHQGP 588
            G PG                N +  PRG  G  G RGP GP         +G PG  GP
Sbjct: 415 GGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGP 474

Query: 589 PGP 591
           PGP
Sbjct: 475 PGP 477



 Score =  226 bits (576), Expect = 9e-59
 Identities = 141/330 (42%), Positives = 161/330 (48%), Gaps = 50/330 (15%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPG-----RPGDLGPVGYQGMKGEKGSRGEKG 311
           G PG++GD GF GE G  G PG +G  G+ G     +PG  G  G  G+ G KG  G  G
Sbjct: 229 GQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPG 288

Query: 312 SRGPKG-----------YKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP 360
             GP G            KGE+G  G+ G  G KGE G  GLPG  G  G  G  GP GP
Sbjct: 289 IAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGP 348

Query: 361 KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGD---EGQPGEPGPPGEKGEAGDEGNPGP 417
           KG PG+ GL G KGE G  G AG PG+ G  G    +G+PG PG PG  G  G+ G PGP
Sbjct: 349 KGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGP 408

Query: 418 DGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQG---REGPVGVPG---------D 465
            G PG  G PG  GP G  G +G  G  GEAGP+G  G     GP+G PG         D
Sbjct: 409 KGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGD 468

Query: 466 PGEAGPIGP-----KGYRGDEGPPGSEGARG---APGPAGPPGDPGLMGERGEDGPAGNG 517
           PG  GP GP     KG  G  GPPG  G RG    PG  GPPG P         GP G  
Sbjct: 469 PGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPP---------GPPGQA 519

Query: 518 T--EGFPGFPGYPGNRGAPGINGTKGYPGL 545
              EGF      P   G P ++  +G  G+
Sbjct: 520 VMPEGFIKAGQRPSLSGTPLVSANQGVTGM 549



 Score =  189 bits (479), Expect = 2e-47
 Identities = 114/252 (45%), Positives = 126/252 (50%), Gaps = 15/252 (5%)

Query: 254 PARGPPGLRGDPGFEGERGKPGLPGEKGE---AGDPGRPGDLGPVGYQGMKGEKGSRGEK 310
           P  G PGL G  G  G  G PG PG KGE   AG PG+PG  GP G  G +G KG  G  
Sbjct: 296 PGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSH 355

Query: 311 GSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370
           G  GPKG  G  G  G  G  G +G  G  G PG  G PG D      GPKG+P   GL 
Sbjct: 356 GLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLD------GPKGNP---GLP 406

Query: 371 GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGER 430
           G KG+PG  G  G PG  GP+G +G PG  G  G +G  G  G  GP G PG  G PG +
Sbjct: 407 GPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSK 466

Query: 431 GPRGTPGTRGPRG--DPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE-GPPGSE 487
           G  G+PG  GP G    G  GP G  G  GP G  G+PG  GP GP G  G    P G  
Sbjct: 467 GDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFI 526

Query: 488 GARGAPGPAGPP 499
            A   P  +G P
Sbjct: 527 KAGQRPSLSGTP 538



 Score =  102 bits (254), Expect = 2e-21
 Identities = 59/128 (46%), Positives = 66/128 (51%), Gaps = 9/128 (7%)

Query: 472 IGPKGYRGDEGPPGSEGARGAPGPAGPP-----GDPGLMGERGEDGPAGN---GTEGFPG 523
           I  +G +G  GPPG  G RG PGP+GPP     G PGL GE G  GP G    G  G PG
Sbjct: 53  IAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPG 112

Query: 524 FPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPG-DDNNDIAPRGVKGAKGYRGPEGPQGP 582
            PG PG RG  G  G  G  GL G  G  G PG      I+  G  G +G  G  GP+G 
Sbjct: 113 LPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGF 172

Query: 583 PGHQGPPG 590
           PG +G PG
Sbjct: 173 PGEKGAPG 180


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score =  293 bits (751), Expect = 4e-79
 Identities = 168/387 (43%), Positives = 197/387 (50%), Gaps = 45/387 (11%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            +G PG  G PG  G+ G PG PG KG  G PG+PG +GP G +G  G+ G  G +G  GP
Sbjct: 984  QGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGP 1043

Query: 316  KGYKGEKGKRGIDGVDGVKGE--------MGYPGLPGCKGSPGFDGIQGPPGPKGD---- 363
             G  G  G+ G  G+ G KG+        +G PGLPG KG PG  G  G PG KG     
Sbjct: 1044 PGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP 1103

Query: 364  --PGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAP 421
              PG  G  G KG+PG  G  G PG  GP G  G PG PG PGE G  G  G+PG  G P
Sbjct: 1104 GLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPP 1163

Query: 422  GERGGPGERGPRGTPGTRGPRGDPGEAGP--------QGDQGREGPVGVPGDPGEAGPIG 473
            GE+G PG+ G  G  G +G  G PG   P         G +G  G  G+PG+PG  GP G
Sbjct: 1164 GEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG 1223

Query: 474  PKGY------RGDEGPPGS-----EGARGAPGPAGPPGDPGLMGERGEDGPAGNG----- 517
              G+      +G  GPPGS     EG +G PGP GPPG PGL G  G  G  GNG     
Sbjct: 1224 EPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGE 1283

Query: 518  -----TEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN--NDIAPRGVKGA 570
                   G PG PG  G++G PG+ G  G PGL G +G+ G PG         P GV G+
Sbjct: 1284 KGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGS 1343

Query: 571  KGYRGPEGPQGPPGHQGPPGPDECEIL 597
             G  G  G  GPPG  G PGP    I+
Sbjct: 1344 AGPEGEPGLIGPPGPPGLPGPSGQSII 1370



 Score =  290 bits (741), Expect = 6e-78
 Identities = 165/373 (44%), Positives = 195/373 (52%), Gaps = 57/373 (15%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPV-----GYQGMKGEKGSRGEKG 311
            G PGL+GD G +G+ G PG  GEKG  G+PG PG  GP+     G +G KGE G  G  G
Sbjct: 917  GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPG 976

Query: 312  SRGPKGYKGE---------KGKRGIDGVDGVKGEMGYPGLPGCKGSPGF----------- 351
              GPKGY+G           G+ G+ G  G KG  G PG PG  G PG            
Sbjct: 977  VSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG 1036

Query: 352  -DGIQGPPGPKG------DPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPG 404
              G++GPPGP G       PG  G KG+KG+PG     G PG  GP G+ G PG PG PG
Sbjct: 1037 PQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISS-IGLPGLPGPKGEPGLPGYPGNPG 1095

Query: 405  EKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPG 464
             KG  GD G PG  G PG +G PG  G  GTPG  GP+G  G  G  G  G  GPVG  G
Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155

Query: 465  DPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAG-----PPGDPGLMGERGEDGPAGNGTE 519
             PG+ GP G KG  G +G PG  G +G PG  G     PPG PGL G++G+      G  
Sbjct: 1156 HPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGD-----GGLP 1210

Query: 520  GFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGP 579
            G PG PG PG +G PG +G   +PG++G  G  G PG              +G +G  GP
Sbjct: 1211 GIPGNPGLPGPKGEPGFHG---FPGVQGPPGPPGSPGP-----------ALEGPKGNPGP 1256

Query: 580  QGPPGHQGPPGPD 592
            QGPPG  G PGP+
Sbjct: 1257 QGPPGRPGLPGPE 1269



 Score =  289 bits (740), Expect = 8e-78
 Identities = 173/382 (45%), Positives = 194/382 (50%), Gaps = 51/382 (13%)

Query: 255  ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMK------------- 301
            A GP G  G PG  G+ G  G PG KGE G  G PG  GP+G  G               
Sbjct: 870  APGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQG 929

Query: 302  --------GEKGSRGEKGSRGPK--------GYKGEKGKRGIDGVDGVKGEMGYPGLPGC 345
                    GEKGS+GE G  GP         G KGEKG+ G+ G+ GV G  GY GLPG 
Sbjct: 930  QPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD 989

Query: 346  KGSPGFD---GIQGPPGPKGDP---------GAFGLKGEKGEPGADGEAGRPGSSGPSGD 393
             G PG     G+ GPPGPKG+P         G  GLKG  G+ G  G  G  G  GPSG 
Sbjct: 990  PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049

Query: 394  EGQPGEPGPPGEKGEAGDEG--NPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQ 451
             GQPG PG PG+KG+ GD G  + G  G PG +G PG  G  G PG +G  GDPG  G  
Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLP 1109

Query: 452  GDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGED 511
            G  G +G  G+PG PG  GP GPKG     GPPG+ G  G PGP G  G PG  G  GE 
Sbjct: 1110 GTPGAKGQPGLPGFPGTPGPPGPKGI---SGPPGNPGLPGEPGPVGGGGHPGQPGPPGEK 1166

Query: 512  GPAGNGTEGFPGFPGYPGNRGAPGIN--GTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKG 569
            G  G   +G PG  G  G  G PG    G  G PGL G +G+ G PG   N   P G KG
Sbjct: 1167 GKPGQ--DGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLP-GPKG 1223

Query: 570  AKGYRGPEGPQGPPGHQGPPGP 591
              G+ G  G QGPPG  G PGP
Sbjct: 1224 EPGFHGFPGVQGPPGPPGSPGP 1245



 Score =  289 bits (740), Expect = 8e-78
 Identities = 168/372 (45%), Positives = 194/372 (52%), Gaps = 39/372 (10%)

Query: 257  GPPGLRGDPG---FEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSR 313
            GP G+ G PG     G+ G PGLPG+KG+ GDPG    +G  G  G KGE G  G  G+ 
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI-SSIGLPGLPGPKGEPGLPGYPGNP 1094

Query: 314  GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKG---DPGAFGLK 370
            G KG  G+ G  G+ G  G KG+ G PG PG  G PG  GI GPPG  G   +PG  G  
Sbjct: 1095 GIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGG 1154

Query: 371  GEKGEPGADGEAGRPGSSG---PSGDEGQPGEPG--------PPGEKGEAGDEGNPGPDG 419
            G  G+PG  GE G+PG  G   P+G +G+PG+PG         PG  G+ GD G PG  G
Sbjct: 1155 GHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPG 1214

Query: 420  APGERGGPGERGPRGTPGTRGPRGDPGEAGP--QGDQGREGPVGVPGDPGEAGPIGPKGY 477
             PG  G  GE G  G PG +GP G PG  GP  +G +G  GP G PG PG  GP GP G 
Sbjct: 1215 NPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGL 1274

Query: 478  ------RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN----GTEGFPGFPGY 527
                  +G++G PG  G  G PG  G  G PGL G  G  G  G     G  G PGFPG 
Sbjct: 1275 PGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGM 1334

Query: 528  PGNRGAPGINGTKGYPGLKGDEGEAGDPGDD------NNDIAPRGV---KGAKGYRGPEG 578
             G  G PG  G +G PGL G  G  G PG          D  P G+    G KG  GP+G
Sbjct: 1335 KGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQG 1394

Query: 579  PQGPPGHQGPPG 590
            PQG PG  GPPG
Sbjct: 1395 PQGLPGPTGPPG 1406



 Score =  286 bits (733), Expect = 5e-77
 Identities = 167/351 (47%), Positives = 185/351 (52%), Gaps = 28/351 (7%)

Query: 257  GPPGLR--GDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314
            GPPGL   G PG  G  G PG PG  G  G PG PG  G  G+ G KGE G  G  G  G
Sbjct: 849  GPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPG 908

Query: 315  PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGS---PGFDGIQGPPGPKGDPGAFGLKG 371
            P G  G  G  G+ G DG++G+ G PG  G KGS   P   G+ GPPGP  DP   G KG
Sbjct: 909  PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEP---GLPGPPGPM-DPNLLGSKG 964

Query: 372  EKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERG 431
            EKGEPG     G PG SGP G +G PG+PG PG  G+ G  G PGP G PG  G PG  G
Sbjct: 965  EKGEPGL---PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIG 1021

Query: 432  PRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE-----GPPGS 486
            P   PG +G  GD G  GPQG +G  GP GVPG PG  G  G KG +GD      G PG 
Sbjct: 1022 P---PGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGL 1078

Query: 487  EGARGAPGPAGPPGDPGLMGERGEDG-------PAGNGTEGFPGFPGYPGNRGAPGINGT 539
             G +G PG  G PG+PG+ G  G+ G       P   G  G PGFPG PG  G  GI+G 
Sbjct: 1079 PGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGP 1138

Query: 540  KGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
             G PGL G+ G  G  G       P G KG  G  G  GP G  G  G PG
Sbjct: 1139 PGNPGLPGEPGPVGGGGHPGQP-GPPGEKGKPGQDGIPGPAGQKGEPGQPG 1188



 Score =  281 bits (720), Expect = 2e-75
 Identities = 167/374 (44%), Positives = 193/374 (51%), Gaps = 46/374 (12%)

Query: 252 CQPARGPPGLRGDPGFEGERGKPGLPGEKGEA-------------GDPGRPGDLGPVGYQ 298
           C+P  GPPG  G PG +G +G+ G+ G+KG+              G PG PG  GP G  
Sbjct: 451 CEP--GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSL 508

Query: 299 GMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMG-------------------Y 339
           G  G+KG +G+ G+ GPKG  G  G  G  G  G KGE G                    
Sbjct: 509 GFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGA 568

Query: 340 PGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE 399
           PGLPG  G+PG DG+ G PGPKG+PG    KGE+G PG  G  G PG+ GP G  G  G 
Sbjct: 569 PGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GP 627

Query: 400 PGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPR-GTPGTRGPRGDPGEAGPQGDQGREG 458
           PGP GEKG  G  GNPG  G PG +G PG+   + G PG  G  G  G+ G  GD G  G
Sbjct: 628 PGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPG 687

Query: 459 PVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NG 517
             G+PG PG  G  G  G  G  GPPG +G  G PGP G PG PG +G  G  GP G  G
Sbjct: 688 QPGLPGIPGSKGEPGIPGI-GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746

Query: 518 TEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPE 577
            +G PGF   PG  G PG+ G KG  G KGD G  G PG       P G  G  G  GP+
Sbjct: 747 PKGEPGF-ALPGPPGPPGLPGFKGALGPKGDRGFPGPPG-------PPGRTGLDGLPGPK 798

Query: 578 GPQGPPGHQGPPGP 591
           G  GP G  GP GP
Sbjct: 799 GDVGPNGQPGPMGP 812



 Score =  281 bits (720), Expect = 2e-75
 Identities = 170/400 (42%), Positives = 199/400 (49%), Gaps = 71/400 (17%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            +G PGL G PG  G +G  GLPG+ G+ G  G+PG  GP    G KG  G  G+ G  GP
Sbjct: 966  KGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGP---PGPKGNPGLPGQPGLIGP 1022

Query: 316  KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFD--------------GIQGPPGPK 361
             G KG  G  G  G  GV+G  G  G+PG  GSPG                G+ G PGPK
Sbjct: 1023 PGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPK 1082

Query: 362  GDPGA------FGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNP 415
            G+PG        G+KG  G+PG  G  G PG+ G  G  G PG PGPPG KG +G  GNP
Sbjct: 1083 GEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNP 1142

Query: 416  GPDGAPGERGG---PGERGPRGTPGTRGPRGDPGEAGPQGD-----------------QG 455
            G  G PG  GG   PG+ GP G  G  G  G PG AG +G+                  G
Sbjct: 1143 GLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSG 1202

Query: 456  REGPVGVPGDPGEAGPIGPK---------GYRGDEGPPGS-----EGARGAPGPAGPPGD 501
            ++G  G+PG PG  G  GPK         G +G  GPPGS     EG +G PGP GPPG 
Sbjct: 1203 QKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGR 1262

Query: 502  PGLMGERGEDGPAGN----------GTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGE 551
            PGL G  G  G  GN          G  G PG PG  G++G PG+ G  G PGL G +G+
Sbjct: 1263 PGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGD 1322

Query: 552  AGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
             G PG         G+KG  G  G  GP+G PG  GPPGP
Sbjct: 1323 PGLPGVPGFP----GMKGPSGVPGSAGPEGEPGLIGPPGP 1358



 Score =  281 bits (718), Expect = 3e-75
 Identities = 166/365 (45%), Positives = 185/365 (50%), Gaps = 52/365 (14%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPG---DLGPVG------YQGMKGEKGSR 307
            G PG +G PG  G  G PG PG KG +G PG PG   + GPVG        G  GEKG  
Sbjct: 1110 GTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKP 1169

Query: 308  GEKGSRGPKGYKGEKGKRG--------IDGVDGVKGEMGYPGLPGCKGSPG--------- 350
            G+ G  GP G KGE G+ G        + G+ G KG+ G PG+PG  G PG         
Sbjct: 1170 GQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHG 1229

Query: 351  FDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAG 410
            F G+QGPPGP G PG   L+G KG PG  G  GRPG  GP G  G PG  G  GEKG  G
Sbjct: 1230 FPGVQGPPGPPGSPGP-ALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPG 1288

Query: 411  DEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAG 470
              G PG  G  G++G PG +G  G PG  G +GDPG  G  G  G +GP GVPG    AG
Sbjct: 1289 QPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGS---AG 1345

Query: 471  PIGPKGYRGDEGPPGSEGARGAP----GPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPG 526
            P G  G  G  GPPG  G  G      G AGPPG PG  G +G  GP G          G
Sbjct: 1346 PEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGP--------QG 1397

Query: 527  YPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQ 586
             PG  G PG  G  G PG  G  G  GDPG          + G  G RG +GP GP G Q
Sbjct: 1398 LPGPTGPPGDPGRNGLPGFDGAGGRKGDPG----------LPGQPGTRGLDGPPGPDGLQ 1447

Query: 587  GPPGP 591
            GPPGP
Sbjct: 1448 GPPGP 1452



 Score =  278 bits (710), Expect = 2e-74
 Identities = 163/379 (43%), Positives = 195/379 (51%), Gaps = 47/379 (12%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPG--RPGDLGPVGYQGMKGEKGSRGE----- 309
            G  GL GDPG  G+ G PG+PG KGE G PG   PG  GP G+ G+ G  G+ G      
Sbjct: 675  GDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIG 734

Query: 310  -KGSRGPKGYKGEKGKRGI--------------DGVDGVKGEMGYPGLPGCKGSPGFDGI 354
             +G  GP G+ G KG+ G                G  G KG+ G+PG PG  G  G DG+
Sbjct: 735  LEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGL 794

Query: 355  QGP---------PGPKGDPG--AFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPG-- 401
             GP         PGP G PG    G++G  G PG  G  G+PG  G  G++G PG PG  
Sbjct: 795  PGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLD 854

Query: 402  ---PPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREG 458
               PPGE+G  G  G PGP G PG  G PG+ G  G PGT+G  G  G  GP G  G  G
Sbjct: 855  VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPG 914

Query: 459  PVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG--- 515
              GVPG  G+ G  G  G  G  G  GS+G  G PGP GP  DP L+G +GE G  G   
Sbjct: 915  RSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPM-DPNLLGSKGEKGEPGLPG 973

Query: 516  -NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGA---K 571
              G  G  G+ G PG+ G PG++G  G PG  G +G  G PG     I P G+KG     
Sbjct: 974  IPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGL-IGPPGLKGTIGDM 1032

Query: 572  GYRGPEGPQGPPGHQGPPG 590
            G+ GP+G +GPPG  G PG
Sbjct: 1033 GFPGPQGVEGPPGPSGVPG 1051



 Score =  274 bits (701), Expect = 3e-73
 Identities = 161/375 (42%), Positives = 189/375 (50%), Gaps = 43/375 (11%)

Query: 255  ARGPPGLR---GDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGM----------- 300
            A GP G R   G PG  G  G  GLPG KG+ G  G+PG +GP G  G+           
Sbjct: 770  ALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI 829

Query: 301  ------KGEKGSRGEKGSRGPKGY-----KGEKGKRGIDGVDGVKGEMGYPGLPGCKGSP 349
                   G  G  GEKG  GP G       GE+G  GI G  G  G  G PGLPG  G+ 
Sbjct: 830  PGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889

Query: 350  GFDGIQ---------GPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEP 400
            GF G +         GPPGP G PG  G+ G KG+ G  G+ G PG +G  G +G+PG P
Sbjct: 890  GFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLP 949

Query: 401  GPPGEK-----GEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQG 455
            GPPG       G  G++G PG  G PG  G  G +G  G PG  G  G PG  GP G +G
Sbjct: 950  GPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKG 1009

Query: 456  REGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG 515
                 G+PG PG  GP G KG  GD G PG +G  G PGP+G PG PG  G  G+ G  G
Sbjct: 1010 NP---GLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG 1066

Query: 516  NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRG 575
            +      G PG PG +G PG+ G  G PG+KG  G+ G PG      A +G  G  G+ G
Sbjct: 1067 DPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGA-KGQPGLPGFPG 1125

Query: 576  PEGPQGPPGHQGPPG 590
              GP GP G  GPPG
Sbjct: 1126 TPGPPGPKGISGPPG 1140



 Score =  271 bits (694), Expect = 2e-72
 Identities = 170/409 (41%), Positives = 194/409 (47%), Gaps = 75/409 (18%)

Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
           RG PGL G PG  G  G  G PG +G+ GD G PG  GP G +G  G  G  G  G  G 
Sbjct: 50  RGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGM 109

Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFG------- 368
            G+ G  G +GI G +G KGE G+PG      SPGF G+QGPPGP G PG  G       
Sbjct: 110 PGHDGAPGPQGIPGCNGTKGERGFPG------SPGFPGLQGPPGPPGIPGMKGEPGSIIM 163

Query: 369 --LKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPP----------------------- 403
             L G KG PG  G  G  G  GP+G  G  G PGPP                       
Sbjct: 164 SSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQ 223

Query: 404 ---GEKGEAGDEGNPGPDG-------------APGERGGPGERGPRGTPGTRGPRGDP-G 446
              GEKGE G +G PGP G               G++G PG+RGP G PG RGP G P G
Sbjct: 224 GPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGG 283

Query: 447 EAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD---EGPPGSEGARGAPGPAGPPGDPG 503
           E G +G+QG  G  G PG  GE G  G  G  GD    G PG +G +G  G  GPPG PG
Sbjct: 284 EKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPG 343

Query: 504 L----------MGERGEDG----PAGNGTEGFPGFPGYPGNRGAPG--INGTKGYPGLKG 547
           L          +GE+G  G    P   G  GFPG  G PG  G PG  + G  G PG  G
Sbjct: 344 LVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPG 403

Query: 548 DEGEAGDPGDDNNDI-APRGVKGAKGYRGPEGPQGPPGHQGPPGPDECE 595
           + G+ GD G     I  P G+ G  G  G  GP GP G   PP  + CE
Sbjct: 404 ERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICE 452



 Score =  270 bits (689), Expect = 7e-72
 Identities = 165/367 (44%), Positives = 187/367 (50%), Gaps = 31/367 (8%)

Query: 254 PARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGR----------PGDLGPVGYQGMKGE 303
           P  GPPG  G+ G +G  G PG PG  G  GDPG+          PG+ G  G  G+ G+
Sbjct: 623 PGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGD 682

Query: 304 KGSRGEKGSRGPKGYKGEKGKRGI--DGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361
            G  G+ G  G  G KGE G  GI   G  G KG  G PG PG  G+PG  G++GPPGP 
Sbjct: 683 PGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPP 742

Query: 362 GDPGAFGLKG--EKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGE---------KGEAG 410
           G PG  G  G    G PG  G  G  G+ GP GD G PG PGPPG          KG+ G
Sbjct: 743 GFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVG 802

Query: 411 DEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVG--VPGDPGE 468
             G PGP G PG   G G +GP G PG  GP G PG  G  G++G  GP G  VPG PGE
Sbjct: 803 PNGQPGPMGPPG-LPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGE 861

Query: 469 AGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGF 524
            G  G  G  G  GPPGS G  G  G +G PG  G MG  G  GP G     G  G PG 
Sbjct: 862 RGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGL 921

Query: 525 PGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGD-DNNDIAPRGVKGAKGYRGPEGPQGPP 583
            G  G +G PG+ G  G  G KG+ G  G PG  D N +  +G KG  G  G  G  GP 
Sbjct: 922 KGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPK 981

Query: 584 GHQGPPG 590
           G+QG PG
Sbjct: 982 GYQGLPG 988



 Score =  268 bits (686), Expect = 1e-71
 Identities = 168/395 (42%), Positives = 196/395 (49%), Gaps = 55/395 (13%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG-- 314
           G PGL G PG  G+ G PGLPG KGE G     G+ GP G  G+ G  G+ G  G  G  
Sbjct: 567 GAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFG 626

Query: 315 PKGYKGEKGKRGI------DGVDGVKGEMGY----PGLPGCKGSPGFDG---IQGPPGPK 361
           P G  GEKG +G+       G+ G KG+ G     PG PG  G+PG DG   + G PG  
Sbjct: 627 PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP 686

Query: 362 GDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAP 421
           G PG  G+ G KGEPG  G  G PG  GP G  G PG PG PG  G  G EG PGP G P
Sbjct: 687 GQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFP 745

Query: 422 GERGGPG-----ERGPRGTPGTRG---PRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIG 473
           G +G PG       GP G PG +G   P+GD G  GP G  GR G  G+PG  G+ GP G
Sbjct: 746 GPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNG 805

Query: 474 PKGYRGDEGPPG-----SEGARGAPGPAGPPGDPGLMGERGEDGPAG---------NGTE 519
             G  G  G PG       G  G PGP G PG  G+ GE+G+ GP G          G+ 
Sbjct: 806 QPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSP 865

Query: 520 GFPGFPGY---PGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN--------------NDI 562
           G PG PG    PG+ G PG  G  G+PG KG+ G  G PG                  D 
Sbjct: 866 GIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDD 925

Query: 563 APRGVKGAKGYRGPEGPQGPPGHQGPPGPDECEIL 597
             +G  G  G  G +G +G PG  GPPGP +  +L
Sbjct: 926 GLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960



 Score =  268 bits (685), Expect = 2e-71
 Identities = 168/384 (43%), Positives = 194/384 (50%), Gaps = 52/384 (13%)

Query: 257 GPPGLRGDPGFEGERGK------------PGLPGEKGEAGDPGRPGDLGPVGYQGMKGEK 304
           GPPG  G PG +GE+G+            PG PG  G  G  G PGD+  + + GMKG+K
Sbjct: 503 GPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDI--LTFPGMKGDK 560

Query: 305 GSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMG---YPGLPGCKGSPGFDGIQGPPGPK 361
           G  G  G+ G  G  G  G+ G+ G+ G KGE G   + G  G  G+PG  G+ G  GP 
Sbjct: 561 GELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPM 620

Query: 362 GDP--GAFGLKGEKGEPGADGEAGRPGSSGPSGDEG----QPGEPGPPGEKGEAGDEGNP 415
           G P  G  G  GEKG  G  G  G+PG  GP GD G    QPG+PG PG  G  GD G P
Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLP 680

Query: 416 GPDGAPGER-----------------GGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREG 458
           G  G PG+                  G PG  GP+G PG  GP G PG  G  G +G  G
Sbjct: 681 GDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPG 740

Query: 459 PVGVPGDPGE-----AGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGD---PGLMGERGE 510
           P G PG  GE      GP GP G  G +G  G +G RG PGP GPPG     GL G +G+
Sbjct: 741 PPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGD 800

Query: 511 DGPAGN-GTEGFPGFP--GYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDI-APRG 566
            GP G  G  G PG P  G  G  G PGI G  G PGL G  GE GDPG    D+  P G
Sbjct: 801 VGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPG 860

Query: 567 VKGAKGYRGPEGPQGPPGHQGPPG 590
            +G+ G  G  GP GPPG  G PG
Sbjct: 861 ERGSPGIPGAPGPIGPPGSPGLPG 884



 Score =  266 bits (679), Expect = 1e-70
 Identities = 178/436 (40%), Positives = 208/436 (47%), Gaps = 108/436 (24%)

Query: 257 GPPGLRGDPG---FEGERGKPGLPGEKGEAGDPGRPGDLGPVG--YQGMKGEKGSRGEKG 311
           GPPG++G PG     G  G PG PG  G  G PG PG  G +G  +QG KGEKG +G +G
Sbjct: 177 GPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQG 236

Query: 312 SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP----KGDPGAF 367
             GP G   E+ KR ID    V+ + G  GLPG +G PG  GI+GPPGP    KG+ G  
Sbjct: 237 PPGPPGQISEQ-KRPID----VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQ 291

Query: 368 GLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA------- 420
           G  G++G+PG DGE G+PG  G  GD G PGEPG  GEKG+ GD G PGP G        
Sbjct: 292 GEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGT 351

Query: 421 ------------------PGERGGPGERGPRGTPGTRG--------PRGDPGEAGPQGDQ 454
                              GERG PG +GP G PG  G        P G PGE G +GD+
Sbjct: 352 GITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDE 411

Query: 455 GREG-----PVGVPGDPGEAGPIGPKGYRGDEGPPGSEGAR-GAPGPAGPPGDPGLMGER 508
           G  G     P G+ G PG  G  GP G  G   PP  E    G PGP G PGD GL GE+
Sbjct: 412 GPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQ 471

Query: 509 GEDGPAGN--------------------------GTEGFP---------------GFPGY 527
           G  G  G+                          G+ GFP               G PG 
Sbjct: 472 GVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI 531

Query: 528 PGNRGAPGINGTKG-------YPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQ 580
           PG  GAPG  G+KG       +PG+KGD+GE G PG       P G  G  G  G  GP+
Sbjct: 532 PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLP-GTPGQDGLPGLPGPK 590

Query: 581 GPP------GHQGPPG 590
           G P      G +GPPG
Sbjct: 591 GEPGGITFKGERGPPG 606



 Score =  265 bits (676), Expect = 2e-70
 Identities = 165/364 (45%), Positives = 186/364 (51%), Gaps = 39/364 (10%)

Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG--S 312
           A G PGL G P   G+ G PGLPG KGE G     G+ GP G  G+ G  G+ G  G   
Sbjct: 568 APGLPGLPGTP---GQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG 624

Query: 313 RGPKGYKGEKGKRGI------DGVDGVKGEMG----YPGLPGCKGSPGFD---GIQGPPG 359
            GP G  GEKG +G+       G+ G KG+ G     PG PG  G+PG D   G+ G PG
Sbjct: 625 FGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPG 684

Query: 360 PKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDG 419
             G PG  G+ G KGEPG  G  G PG  GP G  G PG PG PG  G  G EG PGP G
Sbjct: 685 LPGQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPG 743

Query: 420 APGERGG-----PGERGPRGTPGTR---GPRGDPGEAGPQGDQGREGPVGVPGDPGEAGP 471
            PG +G      PG  GP G PG +   GP+GD G  GP G  GR G  G+PG  G+ GP
Sbjct: 744 FPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGP 803

Query: 472 IGPKGYRGDEGPP-----GSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPG 526
            G  G  G  G P     G  G  G PGP G PG  G+ GE+G+ GP G    G PG  G
Sbjct: 804 NGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERG 863

Query: 527 YPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQ 586
            PG  GAPG  G  G PGL G  G +G PG        +G  G  G  GP GP G PG  
Sbjct: 864 SPGIPGAPGPIGPPGSPGLPGKAGASGFPG-------TKGEMGMMGPPGPPGPLGIPGRS 916

Query: 587 GPPG 590
           G PG
Sbjct: 917 GVPG 920



 Score =  261 bits (666), Expect = 3e-69
 Identities = 176/457 (38%), Positives = 203/457 (44%), Gaps = 124/457 (27%)

Query: 257 GPPGLRGDPG-------------FEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGE 303
           GPPG+RG PG               G+RGKPG  GE G+ G PG PGD G  G  G  GE
Sbjct: 270 GPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGE 329

Query: 304 KGSRGEKGSRGPKGYK----------GEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDG 353
           KG +G+ G  GP G            GEKG  G+ G+ G KGE G+PG+ G  G PG  G
Sbjct: 330 KGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG 389

Query: 354 --IQGPPGPKGDPGAFGLKGEKGEPGA--------DGEAGRPGSSGPSGDEG-------- 395
             + GPPGP G PG  G KG++G PG         DG+ G PG  GP G  G        
Sbjct: 390 AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449

Query: 396 --QPGEPGPPG---------EKGEAGDEGN-------------------PGPDGAPGERG 425
             +PG PGPPG         E+G  GD+G+                   PG  G PG  G
Sbjct: 450 ICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLG 509

Query: 426 GPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGD----------PGEAGPIGPK 475
            PG++G +G  G  GP+G PG  G  G  G  G  G PGD           GE G  G  
Sbjct: 510 FPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAP 569

Query: 476 GYRGDEGPPGSEGARGAPGPAG------------PPGDPGLMGERGEDGPAG-------- 515
           G  G  G PG +G  G PGP G            PPG+PGL G  G  GP G        
Sbjct: 570 GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG 629

Query: 516 -------NGTEGFPGFPGYPGNRGAPGIN-------GTKGYPGLKGDEGEAGDPGDDNND 561
                   G  G PG PG PG +G PG         G  G PG  GD G  GDPG     
Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689

Query: 562 IAPRGVKGAK--------GYRGPEGPQGPPGHQGPPG 590
             P G+ G+K        G  GP GP+G PG  GPPG
Sbjct: 690 GLP-GIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPG 725



 Score =  220 bits (561), Expect = 5e-57
 Identities = 138/348 (39%), Positives = 156/348 (44%), Gaps = 86/348 (24%)

Query: 329 GVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD------------------------- 363
           G+ G KGE G+PGL G  G PGF G +GPPGP+G                          
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP 101

Query: 364 --------------------PGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGP- 402
                               PG  G KGE+G PG+ G  G  G  GP G  G  GEPG  
Sbjct: 102 GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSI 161

Query: 403 -----PGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGR- 456
                PG KG  G  G PG  G PG  G PG  GP G PG  GP G PG  GP+G+ G  
Sbjct: 162 IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLN 221

Query: 457 -EGPVGVPGDPGEAGPIGPKG-------------YRGDEGPPGSEGARGAPGPAGPPGDP 502
            +GP G  G+ G  GP GP G              +GD+G PG  G  G PG  GPPG P
Sbjct: 222 FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPP 281

Query: 503 -GLMGERGEDG-------PAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGD 554
            G  GE+GE G       P  +G  G PG PG PG+ G PG  G  G  G KGD G  G 
Sbjct: 282 GGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGP 341

Query: 555 PG------------DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           PG             +  +I   G+ G KG RG  G QGPPG  GPPG
Sbjct: 342 PGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG 389



 Score =  220 bits (560), Expect = 6e-57
 Identities = 127/275 (46%), Positives = 148/275 (53%), Gaps = 36/275 (13%)

Query: 253  QPARGPPGLRGDPGFEGERGK---------PGLPGEKGEAGDPGRPGDLGPVGYQG---- 299
            QP  G PG  G PG  G++G          PGLPG KGE G  G PG  GP G  G    
Sbjct: 1186 QPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP 1245

Query: 300  -MKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPP 358
             ++G KG+ G +G  G  G  G +G  G+ G  G+KGE G PG PG  G PG  G QGPP
Sbjct: 1246 ALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPP 1305

Query: 359  GPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPS------GDEGQP---GEPGPPGEKGEA 409
            G +G+PG  GL G KG+PG  G  G PG  GPS      G EG+P   G PGPPG  G +
Sbjct: 1306 GLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPS 1365

Query: 410  -------GDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGV 462
                   GD G PG  G PG +G PG +GP+G PG  GP GDPG  G  G  G  G  G 
Sbjct: 1366 GQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGD 1425

Query: 463  PGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAG 497
            PG PG+ G       RG +GPPG +G +G PGP G
Sbjct: 1426 PGLPGQPGT------RGLDGPPGPDGLQGPPGPPG 1454



 Score =  161 bits (408), Expect = 3e-39
 Identities = 103/251 (41%), Positives = 115/251 (45%), Gaps = 36/251 (14%)

Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436
           G   EA       P       G  G  GE+G  G EG+PG  G PG  G PG RG +G  
Sbjct: 21  GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80

Query: 437 GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY------RGDEGPPGSEGAR 490
           G  GP G  G  GP G  G  G  G+PG PG  G  GP+G       +G+ G PGS G  
Sbjct: 81  GIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP 140

Query: 491 GAPGPAGPPGDPGLMGERGE------DGPAGN-GTEGFPGFPGYPGNRGAPGINGTKGYP 543
           G  GP GPPG PG+ GE G        GP GN G  G PG  G PG  G PG  G  G P
Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPP 200

Query: 544 GLKGDEGEAGDPGDDN----NDIAPRGVKGAKGYRGPEGP-------------------Q 580
           GL G  G  G PG       N   P+G KG +G +GP GP                   Q
Sbjct: 201 GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQ 260

Query: 581 GPPGHQGPPGP 591
           G PG +GPPGP
Sbjct: 261 GLPGDRGPPGP 271



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 30/75 (40%), Positives = 36/75 (48%), Gaps = 3/75 (4%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            +G PG +G  G  G  G PG PG  G    PG  G  G  G  G+ G+ G+RG  G  GP
Sbjct: 1387 KGLPGPQGPQGLPGPTGPPGDPGRNGL---PGFDGAGGRKGDPGLPGQPGTRGLDGPPGP 1443

Query: 316  KGYKGEKGKRGIDGV 330
             G +G  G  G   V
Sbjct: 1444 DGLQGPPGPPGTSSV 1458


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  292 bits (748), Expect = 1e-78
 Identities = 175/377 (46%), Positives = 199/377 (52%), Gaps = 39/377 (10%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            GPPG +G+PG  G+ G  G PG KG  GD G PG   P G +G  G  G  G+ GS G  
Sbjct: 1003 GPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG---PQGVEGPPGPSGVPGQPGSPGLP 1059

Query: 317  GYKGEKGKRGID-----GVDGVKGEMG---YPGLPGCKGS---PGFDGIQGPPGPKGDPG 365
            G KG+KG  GI      G+ G KGE G   YPG PG KGS   PG  G+ G PG KG PG
Sbjct: 1060 GQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPG 1119

Query: 366  AFGLKGEKGEPGADGEAGRPGSSG------PSGDEGQPGEPGPPGEKGEAGDEGNPGPDG 419
              G  G  G PG  G +G PG+ G      P G  G PG+PGPPGEKG+ G +G PGP G
Sbjct: 1120 LPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG 1179

Query: 420  APGERGGPG--ERGPRGTPGTRGPRGD---------PGEAGPQGDQGREGPVGV---PGD 465
              GE G PG    GP G PG  G +GD         PG  GP+G+ G  G  GV   PG 
Sbjct: 1180 QKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGP 1239

Query: 466  PGEAGPI--GPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN-GTEGFP 522
            PG  GP   GPKG  G +GPPG  G  G  G  GP G PGL G  G  G  GN G  G P
Sbjct: 1240 PGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLP 1299

Query: 523  GFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN--NDIAPRGVKGAKGYRGPEGPQ 580
            G PG  G++G PG+ G  G PGL G +G+ G PG         P GV G+ G  G  G  
Sbjct: 1300 GLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLI 1359

Query: 581  GPPGHQGPPGPDECEIL 597
            GPPG  G PGP    I+
Sbjct: 1360 GPPGPPGLPGPSGQSII 1376



 Score =  290 bits (742), Expect = 5e-78
 Identities = 163/346 (47%), Positives = 189/346 (54%), Gaps = 26/346 (7%)

Query: 253  QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312
            Q   GPPG  G P   G+ G PGLPG+KG+ GDPG    +  +G  G+ G KG  G  G 
Sbjct: 1038 QGVEGPPGPSGVP---GQPGSPGLPGQKGDKGDPG----ISSIGLPGLPGPKGEPGLPGY 1090

Query: 313  RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372
             G  G KG  G  G+ G+ G  G  G PGLPG  G+P      GPPGPKG  G  G  G 
Sbjct: 1091 PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTP------GPPGPKGISGPPGNPGL 1144

Query: 373  KGEPGADGEAGRPGSSGPSGDEGQPGE---PGPPGEKGEAGDE--GNPGPDGAPGERGGP 427
             GEPG  G  G PG  GP G++G+PG+   PGP G+KGE G    GNPGP G PG  G  
Sbjct: 1145 PGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQK 1204

Query: 428  GERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEA--GPIGPKGYRGDEGPPG 485
            G+ G  G PG  G  G  GE G  G  G +GP G PG PG A  GP G  G +G  G PG
Sbjct: 1205 GDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPG 1264

Query: 486  SEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGL 545
              G +G PGP GPPG PG  G +GE G    G  G PG PG  G++G PG+ G  G PGL
Sbjct: 1265 PTGFQGLPGPEGPPGLPGNGGIKGEKG--NPGQPGLPGLPGLKGDQGPPGLQGNPGRPGL 1322

Query: 546  KGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
             G +G+ G PG         G+KG  G  G  GP+G PG  GPPGP
Sbjct: 1323 NGMKGDPGLPGVPGFP----GMKGPSGVPGSAGPEGEPGLIGPPGP 1364



 Score =  289 bits (740), Expect = 8e-78
 Identities = 173/382 (45%), Positives = 194/382 (50%), Gaps = 51/382 (13%)

Query: 255  ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMK------------- 301
            A GP G  G PG  G+ G  G PG KGE G  G PG  GP+G  G               
Sbjct: 870  APGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQG 929

Query: 302  --------GEKGSRGEKGSRGPK--------GYKGEKGKRGIDGVDGVKGEMGYPGLPGC 345
                    GEKGS+GE G  GP         G KGEKG+ G+ G+ GV G  GY GLPG 
Sbjct: 930  QPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD 989

Query: 346  KGSPGFD---GIQGPPGPKGDP---------GAFGLKGEKGEPGADGEAGRPGSSGPSGD 393
             G PG     G+ GPPGPKG+P         G  GLKG  G+ G  G  G  G  GPSG 
Sbjct: 990  PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049

Query: 394  EGQPGEPGPPGEKGEAGDEG--NPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQ 451
             GQPG PG PG+KG+ GD G  + G  G PG +G PG  G  G PG +G  GDPG  G  
Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLP 1109

Query: 452  GDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGED 511
            G  G +G  G+PG PG  GP GPKG     GPPG+ G  G PGP G  G PG  G  GE 
Sbjct: 1110 GTPGAKGQPGLPGFPGTPGPPGPKGI---SGPPGNPGLPGEPGPVGGGGHPGQPGPPGEK 1166

Query: 512  GPAGNGTEGFPGFPGYPGNRGAPGIN--GTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKG 569
            G  G   +G PG  G  G  G PG    G  G PGL G +G+ G PG   N   P G KG
Sbjct: 1167 GKPGQ--DGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLP-GPKG 1223

Query: 570  AKGYRGPEGPQGPPGHQGPPGP 591
              G+ G  G QGPPG  G PGP
Sbjct: 1224 EPGFHGFPGVQGPPGPPGSPGP 1245



 Score =  286 bits (733), Expect = 5e-77
 Identities = 167/351 (47%), Positives = 185/351 (52%), Gaps = 28/351 (7%)

Query: 257  GPPGLR--GDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG 314
            GPPGL   G PG  G  G PG PG  G  G PG PG  G  G+ G KGE G  G  G  G
Sbjct: 849  GPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPG 908

Query: 315  PKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGS---PGFDGIQGPPGPKGDPGAFGLKG 371
            P G  G  G  G+ G DG++G+ G PG  G KGS   P   G+ GPPGP  DP   G KG
Sbjct: 909  PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEP---GLPGPPGPM-DPNLLGSKG 964

Query: 372  EKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERG 431
            EKGEPG     G PG SGP G +G PG+PG PG  G+ G  G PGP G PG  G PG  G
Sbjct: 965  EKGEPGL---PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIG 1021

Query: 432  PRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE-----GPPGS 486
            P   PG +G  GD G  GPQG +G  GP GVPG PG  G  G KG +GD      G PG 
Sbjct: 1022 P---PGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGL 1078

Query: 487  EGARGAPGPAGPPGDPGLMGERGEDG-------PAGNGTEGFPGFPGYPGNRGAPGINGT 539
             G +G PG  G PG+PG+ G  G+ G       P   G  G PGFPG PG  G  GI+G 
Sbjct: 1079 PGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGP 1138

Query: 540  KGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
             G PGL G+ G  G  G       P G KG  G  G  GP G  G  G PG
Sbjct: 1139 PGNPGLPGEPGPVGGGGHPGQP-GPPGEKGKPGQDGIPGPAGQKGEPGQPG 1188



 Score =  285 bits (728), Expect = 2e-76
 Identities = 167/362 (46%), Positives = 192/362 (53%), Gaps = 29/362 (8%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPV-----GYQGMKGEKGSRGEKG 311
            G PGL+GD G +G+ G PG  GEKG  G+PG PG  GP+     G +G KGE G  G  G
Sbjct: 917  GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPG 976

Query: 312  SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD------PG 365
              GPKGY+G  G  G  G+ G  G  G PG  G  G PG  G+ GPPG KG       PG
Sbjct: 977  VSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG 1036

Query: 366  AFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE-----PGPPGEKGEAGDEGNPGPDGA 420
              G++G  G  G  G+ G PG  G  GD+G PG      PG PG KGE G  G PG  G 
Sbjct: 1037 PQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGI 1096

Query: 421  PGERGGPGERGPRGTPGTRGP---RGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY 477
             G  G PG  G  GTPG +G     G PG  GP G +G  GP G PG PGE GP+G  G+
Sbjct: 1097 KGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGH 1156

Query: 478  RGDEGPPGSE---GARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGFPGYPGN 530
             G  GPPG +   G  G PGPAG  G+PG  G  G  GP G    +G +G  G PG PGN
Sbjct: 1157 PGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG-FGNPGPPGLPGLSGQKGDGGLPGIPGN 1215

Query: 531  RGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
             G PG  G  G+ G  G +G  G PG      A  G KG  G +GP G  GP G QG PG
Sbjct: 1216 PGLPGPKGEPGFHGFPGVQGPPGPPGSPGP--ALEGPKGNPGPQGPPGRPGPTGFQGLPG 1273

Query: 591  PD 592
            P+
Sbjct: 1274 PE 1275



 Score =  282 bits (721), Expect = 1e-75
 Identities = 168/360 (46%), Positives = 190/360 (52%), Gaps = 27/360 (7%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
            G PGL G PG  G +G+PGLPG  G  G PG  G  GP G  G+ GE G  G  G  G  
Sbjct: 1101 GDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQP 1160

Query: 317  GYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD------PGAFGLK 370
            G  GEKGK G DG+ G  G+ G PG PG  G+PG  G+ G  G KGD      PG  GL 
Sbjct: 1161 GPPGEKGKPGQDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGLPGIPGNPGLP 1219

Query: 371  GEKGEPG------ADGEAGRPGSSGPS--GDEGQPGEPGPPGEKGEAGDEGNPGPDGAPG 422
            G KGEPG        G  G PGS GP+  G +G PG  GPPG  G  G +G PGP+G PG
Sbjct: 1220 GPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPG 1279

Query: 423  ERGGPGERGPRGTPGTRGP------RGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKG 476
              G  G +G +G PG  G       +GD G  G QG+ GR G  G+ GDPG  G  G  G
Sbjct: 1280 LPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPG 1339

Query: 477  YRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGI 536
             +G  G PGS G  G PG  GPPG PGL G  G+      G  G PG PG PG +G PG 
Sbjct: 1340 MKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQ-SIIIKGDAGPPGIPGQPGLKGLPGP 1398

Query: 537  NGTKGYP---GLKGDEGEAGDPGDD--NNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGP 591
             G +G P   G  GD G  G PG D         G+ G  G RG +GP GP G QGPPGP
Sbjct: 1399 QGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGP 1458



 Score =  281 bits (720), Expect = 2e-75
 Identities = 167/374 (44%), Positives = 193/374 (51%), Gaps = 46/374 (12%)

Query: 252 CQPARGPPGLRGDPGFEGERGKPGLPGEKGEA-------------GDPGRPGDLGPVGYQ 298
           C+P  GPPG  G PG +G +G+ G+ G+KG+              G PG PG  GP G  
Sbjct: 451 CEP--GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSL 508

Query: 299 GMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMG-------------------Y 339
           G  G+KG +G+ G+ GPKG  G  G  G  G  G KGE G                    
Sbjct: 509 GFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGA 568

Query: 340 PGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGE 399
           PGLPG  G+PG DG+ G PGPKG+PG    KGE+G PG  G  G PG+ GP G  G  G 
Sbjct: 569 PGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GP 627

Query: 400 PGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPR-GTPGTRGPRGDPGEAGPQGDQGREG 458
           PGP GEKG  G  GNPG  G PG +G PG+   + G PG  G  G  G+ G  GD G  G
Sbjct: 628 PGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPG 687

Query: 459 PVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG-NG 517
             G+PG PG  G  G  G  G  GPPG +G  G PGP G PG PG +G  G  GP G  G
Sbjct: 688 QPGLPGIPGSKGEPGIPGI-GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746

Query: 518 TEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPE 577
            +G PGF   PG  G PG+ G KG  G KGD G  G PG       P G  G  G  GP+
Sbjct: 747 PKGEPGF-ALPGPPGPPGLPGFKGALGPKGDRGFPGPPG-------PPGRTGLDGLPGPK 798

Query: 578 GPQGPPGHQGPPGP 591
           G  GP G  GP GP
Sbjct: 799 GDVGPNGQPGPMGP 812



 Score =  280 bits (716), Expect = 5e-75
 Identities = 167/389 (42%), Positives = 194/389 (49%), Gaps = 54/389 (13%)

Query: 257  GPPGLRGDPG---FEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSR 313
            GP G+ G PG     G+ G PGLPG+KG+ GDPG    +G  G  G KGE G  G  G+ 
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI-SSIGLPGLPGPKGEPGLPGYPGNP 1094

Query: 314  GPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKG---DPGAFGLK 370
            G KG  G+ G  G+ G  G KG+ G PG PG  G PG  GI GPPG  G   +PG  G  
Sbjct: 1095 GIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGG 1154

Query: 371  GEKGEPGADGEAGRPGSSG---PSGDEGQPGEPG-----PPGEKGEAGDEGN-------- 414
            G  G+PG  GE G+PG  G   P+G +G+PG+PG     PPG  G +G +G+        
Sbjct: 1155 GHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPG 1214

Query: 415  ----PGPDGAPGERGGPGERGPRGTPGTRGP--RGDPGEAGPQGDQGREGPVGVPGDPGE 468
                PGP G PG  G PG +GP G PG+ GP   G  G  GPQG  GR GP G  G PG 
Sbjct: 1215 NPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGP 1274

Query: 469  AGPIGPKG---YRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGN----GTEGF 521
             GP G  G    +G++G PG  G  G PG  G  G PGL G  G  G  G     G  G 
Sbjct: 1275 EGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGV 1334

Query: 522  PGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNN------DIAPRGVKGAKGYRG 575
            PGFPG  G  G PG  G +G PGL G  G  G PG          D  P G+ G  G +G
Sbjct: 1335 PGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKG 1394

Query: 576  ------------PEGPQGPPGHQGPPGPD 592
                        P GP G PG  G PG D
Sbjct: 1395 LPGPQGPQGLPGPTGPPGDPGRNGLPGFD 1423



 Score =  278 bits (710), Expect = 2e-74
 Identities = 163/379 (43%), Positives = 195/379 (51%), Gaps = 47/379 (12%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPG--RPGDLGPVGYQGMKGEKGSRGE----- 309
            G  GL GDPG  G+ G PG+PG KGE G PG   PG  GP G+ G+ G  G+ G      
Sbjct: 675  GDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIG 734

Query: 310  -KGSRGPKGYKGEKGKRGI--------------DGVDGVKGEMGYPGLPGCKGSPGFDGI 354
             +G  GP G+ G KG+ G                G  G KG+ G+PG PG  G  G DG+
Sbjct: 735  LEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGL 794

Query: 355  QGP---------PGPKGDPG--AFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPG-- 401
             GP         PGP G PG    G++G  G PG  G  G+PG  G  G++G PG PG  
Sbjct: 795  PGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLD 854

Query: 402  ---PPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREG 458
               PPGE+G  G  G PGP G PG  G PG+ G  G PGT+G  G  G  GP G  G  G
Sbjct: 855  VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPG 914

Query: 459  PVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG--- 515
              GVPG  G+ G  G  G  G  G  GS+G  G PGP GP  DP L+G +GE G  G   
Sbjct: 915  RSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPM-DPNLLGSKGEKGEPGLPG 973

Query: 516  -NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGA---K 571
              G  G  G+ G PG+ G PG++G  G PG  G +G  G PG     I P G+KG     
Sbjct: 974  IPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGL-IGPPGLKGTIGDM 1032

Query: 572  GYRGPEGPQGPPGHQGPPG 590
            G+ GP+G +GPPG  G PG
Sbjct: 1033 GFPGPQGVEGPPGPSGVPG 1051



 Score =  274 bits (701), Expect = 3e-73
 Identities = 161/375 (42%), Positives = 189/375 (50%), Gaps = 43/375 (11%)

Query: 255  ARGPPGLR---GDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGM----------- 300
            A GP G R   G PG  G  G  GLPG KG+ G  G+PG +GP G  G+           
Sbjct: 770  ALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI 829

Query: 301  ------KGEKGSRGEKGSRGPKGY-----KGEKGKRGIDGVDGVKGEMGYPGLPGCKGSP 349
                   G  G  GEKG  GP G       GE+G  GI G  G  G  G PGLPG  G+ 
Sbjct: 830  PGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889

Query: 350  GFDGIQ---------GPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEP 400
            GF G +         GPPGP G PG  G+ G KG+ G  G+ G PG +G  G +G+PG P
Sbjct: 890  GFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLP 949

Query: 401  GPPGEK-----GEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQG 455
            GPPG       G  G++G PG  G PG  G  G +G  G PG  G  G PG  GP G +G
Sbjct: 950  GPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKG 1009

Query: 456  REGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG 515
                 G+PG PG  GP G KG  GD G PG +G  G PGP+G PG PG  G  G+ G  G
Sbjct: 1010 NP---GLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG 1066

Query: 516  NGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRG 575
            +      G PG PG +G PG+ G  G PG+KG  G+ G PG      A +G  G  G+ G
Sbjct: 1067 DPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGA-KGQPGLPGFPG 1125

Query: 576  PEGPQGPPGHQGPPG 590
              GP GP G  GPPG
Sbjct: 1126 TPGPPGPKGISGPPG 1140



 Score =  271 bits (694), Expect = 2e-72
 Identities = 170/409 (41%), Positives = 194/409 (47%), Gaps = 75/409 (18%)

Query: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
           RG PGL G PG  G  G  G PG +G+ GD G PG  GP G +G  G  G  G  G  G 
Sbjct: 50  RGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGM 109

Query: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFG------- 368
            G+ G  G +GI G +G KGE G+PG      SPGF G+QGPPGP G PG  G       
Sbjct: 110 PGHDGAPGPQGIPGCNGTKGERGFPG------SPGFPGLQGPPGPPGIPGMKGEPGSIIM 163

Query: 369 --LKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPP----------------------- 403
             L G KG PG  G  G  G  GP+G  G  G PGPP                       
Sbjct: 164 SSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQ 223

Query: 404 ---GEKGEAGDEGNPGPDG-------------APGERGGPGERGPRGTPGTRGPRGDP-G 446
              GEKGE G +G PGP G               G++G PG+RGP G PG RGP G P G
Sbjct: 224 GPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGG 283

Query: 447 EAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD---EGPPGSEGARGAPGPAGPPGDPG 503
           E G +G+QG  G  G PG  GE G  G  G  GD    G PG +G +G  G  GPPG PG
Sbjct: 284 EKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPG 343

Query: 504 L----------MGERGEDG----PAGNGTEGFPGFPGYPGNRGAPG--INGTKGYPGLKG 547
           L          +GE+G  G    P   G  GFPG  G PG  G PG  + G  G PG  G
Sbjct: 344 LVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPG 403

Query: 548 DEGEAGDPGDDNNDI-APRGVKGAKGYRGPEGPQGPPGHQGPPGPDECE 595
           + G+ GD G     I  P G+ G  G  G  GP GP G   PP  + CE
Sbjct: 404 ERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICE 452



 Score =  270 bits (689), Expect = 7e-72
 Identities = 165/367 (44%), Positives = 187/367 (50%), Gaps = 31/367 (8%)

Query: 254 PARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGR----------PGDLGPVGYQGMKGE 303
           P  GPPG  G+ G +G  G PG PG  G  GDPG+          PG+ G  G  G+ G+
Sbjct: 623 PGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGD 682

Query: 304 KGSRGEKGSRGPKGYKGEKGKRGI--DGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPK 361
            G  G+ G  G  G KGE G  GI   G  G KG  G PG PG  G+PG  G++GPPGP 
Sbjct: 683 PGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPP 742

Query: 362 GDPGAFGLKG--EKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGE---------KGEAG 410
           G PG  G  G    G PG  G  G  G+ GP GD G PG PGPPG          KG+ G
Sbjct: 743 GFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVG 802

Query: 411 DEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVG--VPGDPGE 468
             G PGP G PG   G G +GP G PG  GP G PG  G  G++G  GP G  VPG PGE
Sbjct: 803 PNGQPGPMGPPG-LPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGE 861

Query: 469 AGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAG----NGTEGFPGF 524
            G  G  G  G  GPPGS G  G  G +G PG  G MG  G  GP G     G  G PG 
Sbjct: 862 RGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGL 921

Query: 525 PGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGD-DNNDIAPRGVKGAKGYRGPEGPQGPP 583
            G  G +G PG+ G  G  G KG+ G  G PG  D N +  +G KG  G  G  G  GP 
Sbjct: 922 KGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPK 981

Query: 584 GHQGPPG 590
           G+QG PG
Sbjct: 982 GYQGLPG 988



 Score =  268 bits (686), Expect = 1e-71
 Identities = 168/395 (42%), Positives = 196/395 (49%), Gaps = 55/395 (13%)

Query: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRG-- 314
           G PGL G PG  G+ G PGLPG KGE G     G+ GP G  G+ G  G+ G  G  G  
Sbjct: 567 GAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFG 626

Query: 315 PKGYKGEKGKRGI------DGVDGVKGEMGY----PGLPGCKGSPGFDG---IQGPPGPK 361
           P G  GEKG +G+       G+ G KG+ G     PG PG  G+PG DG   + G PG  
Sbjct: 627 PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP 686

Query: 362 GDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAP 421
           G PG  G+ G KGEPG  G  G PG  GP G  G PG PG PG  G  G EG PGP G P
Sbjct: 687 GQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFP 745

Query: 422 GERGGPG-----ERGPRGTPGTRG---PRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIG 473
           G +G PG       GP G PG +G   P+GD G  GP G  GR G  G+PG  G+ GP G
Sbjct: 746 GPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNG 805

Query: 474 PKGYRGDEGPPG-----SEGARGAPGPAGPPGDPGLMGERGEDGPAG---------NGTE 519
             G  G  G PG       G  G PGP G PG  G+ GE+G+ GP G          G+ 
Sbjct: 806 QPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSP 865

Query: 520 GFPGFPGY---PGNRGAPGINGTKGYPGLKGDEGEAGDPGDDN--------------NDI 562
           G PG PG    PG+ G PG  G  G+PG KG+ G  G PG                  D 
Sbjct: 866 GIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDD 925

Query: 563 APRGVKGAKGYRGPEGPQGPPGHQGPPGPDECEIL 597
             +G  G  G  G +G +G PG  GPPGP +  +L
Sbjct: 926 GLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960



 Score =  268 bits (685), Expect = 2e-71
 Identities = 168/384 (43%), Positives = 194/384 (50%), Gaps = 52/384 (13%)

Query: 257 GPPGLRGDPGFEGERGK------------PGLPGEKGEAGDPGRPGDLGPVGYQGMKGEK 304
           GPPG  G PG +GE+G+            PG PG  G  G  G PGD+  + + GMKG+K
Sbjct: 503 GPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDI--LTFPGMKGDK 560

Query: 305 GSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMG---YPGLPGCKGSPGFDGIQGPPGPK 361
           G  G  G+ G  G  G  G+ G+ G+ G KGE G   + G  G  G+PG  G+ G  GP 
Sbjct: 561 GELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPM 620

Query: 362 GDP--GAFGLKGEKGEPGADGEAGRPGSSGPSGDEG----QPGEPGPPGEKGEAGDEGNP 415
           G P  G  G  GEKG  G  G  G+PG  GP GD G    QPG+PG PG  G  GD G P
Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLP 680

Query: 416 GPDGAPGER-----------------GGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREG 458
           G  G PG+                  G PG  GP+G PG  GP G PG  G  G +G  G
Sbjct: 681 GDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPG 740

Query: 459 PVGVPGDPGE-----AGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGD---PGLMGERGE 510
           P G PG  GE      GP GP G  G +G  G +G RG PGP GPPG     GL G +G+
Sbjct: 741 PPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGD 800

Query: 511 DGPAGN-GTEGFPGFP--GYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDI-APRG 566
            GP G  G  G PG P  G  G  G PGI G  G PGL G  GE GDPG    D+  P G
Sbjct: 801 VGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPG 860

Query: 567 VKGAKGYRGPEGPQGPPGHQGPPG 590
            +G+ G  G  GP GPPG  G PG
Sbjct: 861 ERGSPGIPGAPGPIGPPGSPGLPG 884



 Score =  266 bits (679), Expect = 1e-70
 Identities = 178/436 (40%), Positives = 208/436 (47%), Gaps = 108/436 (24%)

Query: 257 GPPGLRGDPG---FEGERGKPGLPGEKGEAGDPGRPGDLGPVG--YQGMKGEKGSRGEKG 311
           GPPG++G PG     G  G PG PG  G  G PG PG  G +G  +QG KGEKG +G +G
Sbjct: 177 GPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQG 236

Query: 312 SRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP----KGDPGAF 367
             GP G   E+ KR ID    V+ + G  GLPG +G PG  GI+GPPGP    KG+ G  
Sbjct: 237 PPGPPGQISEQ-KRPID----VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQ 291

Query: 368 GLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA------- 420
           G  G++G+PG DGE G+PG  G  GD G PGEPG  GEKG+ GD G PGP G        
Sbjct: 292 GEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGT 351

Query: 421 ------------------PGERGGPGERGPRGTPGTRG--------PRGDPGEAGPQGDQ 454
                              GERG PG +GP G PG  G        P G PGE G +GD+
Sbjct: 352 GITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDE 411

Query: 455 GREG-----PVGVPGDPGEAGPIGPKGYRGDEGPPGSEGAR-GAPGPAGPPGDPGLMGER 508
           G  G     P G+ G PG  G  GP G  G   PP  E    G PGP G PGD GL GE+
Sbjct: 412 GPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQ 471

Query: 509 GEDGPAGN--------------------------GTEGFP---------------GFPGY 527
           G  G  G+                          G+ GFP               G PG 
Sbjct: 472 GVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI 531

Query: 528 PGNRGAPGINGTKG-------YPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQ 580
           PG  GAPG  G+KG       +PG+KGD+GE G PG       P G  G  G  G  GP+
Sbjct: 532 PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLP-GTPGQDGLPGLPGPK 590

Query: 581 GPP------GHQGPPG 590
           G P      G +GPPG
Sbjct: 591 GEPGGITFKGERGPPG 606



 Score =  265 bits (677), Expect = 2e-70
 Identities = 160/379 (42%), Positives = 189/379 (49%), Gaps = 54/379 (14%)

Query: 257  GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPG---DLGPVG------YQGMKGEKGSR 307
            G PG +G PG  G  G PG PG KG +G PG PG   + GPVG        G  GEKG  
Sbjct: 1110 GTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKP 1169

Query: 308  GEKGSRGPKGYKGEKGKRG--------IDGVDGVKGEMGYPGLPGCKGSPG--------- 350
            G+ G  GP G KGE G+ G        + G+ G KG+ G PG+PG  G PG         
Sbjct: 1170 GQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHG 1229

Query: 351  FDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAG 410
            F G+QGPPGP G PG   L+G KG PG  G  GRPG +G  G  G  G PG PG  G  G
Sbjct: 1230 FPGVQGPPGPPGSPGP-ALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKG 1288

Query: 411  DEGNPGPDGAPG------ERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPG 464
            ++GNPG  G PG      ++G PG +G  G PG  G +GDPG  G  G  G +GP GVPG
Sbjct: 1289 EKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPG 1348

Query: 465  ------DPGEAGPIGPKGY----------RGDEGPPG---SEGARGAPGPAGPPGDPGLM 505
                  +PG  GP GP G           +GD GPPG     G +G PGP GP G PG  
Sbjct: 1349 SAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPT 1408

Query: 506  GERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPR 565
            G  G+  P  NG  GF G  G  G+ G PG  GT+G  G  G +G  G PG         
Sbjct: 1409 GPPGD--PGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAH 1466

Query: 566  GVKGAKGYRGPEGPQGPPG 584
            G    +  +  + PQ P G
Sbjct: 1467 GFLITRHSQTTDAPQCPQG 1485



 Score =  265 bits (676), Expect = 2e-70
 Identities = 165/364 (45%), Positives = 186/364 (51%), Gaps = 39/364 (10%)

Query: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKG--S 312
           A G PGL G P   G+ G PGLPG KGE G     G+ GP G  G+ G  G+ G  G   
Sbjct: 568 APGLPGLPGTP---GQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG 624

Query: 313 RGPKGYKGEKGKRGI------DGVDGVKGEMG----YPGLPGCKGSPGFD---GIQGPPG 359
            GP G  GEKG +G+       G+ G KG+ G     PG PG  G+PG D   G+ G PG
Sbjct: 625 FGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPG 684

Query: 360 PKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDG 419
             G PG  G+ G KGEPG  G  G PG  GP G  G PG PG PG  G  G EG PGP G
Sbjct: 685 LPGQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPG 743

Query: 420 APGERGG-----PGERGPRGTPGTR---GPRGDPGEAGPQGDQGREGPVGVPGDPGEAGP 471
            PG +G      PG  GP G PG +   GP+GD G  GP G  GR G  G+PG  G+ GP
Sbjct: 744 FPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGP 803

Query: 472 IGPKGYRGDEGPP-----GSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPG 526
            G  G  G  G P     G  G  G PGP G PG  G+ GE+G+ GP G    G PG  G
Sbjct: 804 NGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERG 863

Query: 527 YPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQ 586
            PG  GAPG  G  G PGL G  G +G PG        +G  G  G  GP GP G PG  
Sbjct: 864 SPGIPGAPGPIGPPGSPGLPGKAGASGFPG-------TKGEMGMMGPPGPPGPLGIPGRS 916

Query: 587 GPPG 590
           G PG
Sbjct: 917 GVPG 920



 Score =  261 bits (666), Expect = 3e-69
 Identities = 176/457 (38%), Positives = 203/457 (44%), Gaps = 124/457 (27%)

Query: 257 GPPGLRGDPG-------------FEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGE 303
           GPPG+RG PG               G+RGKPG  GE G+ G PG PGD G  G  G  GE
Sbjct: 270 GPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGE 329

Query: 304 KGSRGEKGSRGPKGYK----------GEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDG 353
           KG +G+ G  GP G            GEKG  G+ G+ G KGE G+PG+ G  G PG  G
Sbjct: 330 KGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG 389

Query: 354 --IQGPPGPKGDPGAFGLKGEKGEPGA--------DGEAGRPGSSGPSGDEG-------- 395
             + GPPGP G PG  G KG++G PG         DG+ G PG  GP G  G        
Sbjct: 390 AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449

Query: 396 --QPGEPGPPG---------EKGEAGDEGN-------------------PGPDGAPGERG 425
             +PG PGPPG         E+G  GD+G+                   PG  G PG  G
Sbjct: 450 ICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLG 509

Query: 426 GPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGD----------PGEAGPIGPK 475
            PG++G +G  G  GP+G PG  G  G  G  G  G PGD           GE G  G  
Sbjct: 510 FPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAP 569

Query: 476 GYRGDEGPPGSEGARGAPGPAG------------PPGDPGLMGERGEDGPAG-------- 515
           G  G  G PG +G  G PGP G            PPG+PGL G  G  GP G        
Sbjct: 570 GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG 629

Query: 516 -------NGTEGFPGFPGYPGNRGAPGIN-------GTKGYPGLKGDEGEAGDPGDDNND 561
                   G  G PG PG PG +G PG         G  G PG  GD G  GDPG     
Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689

Query: 562 IAPRGVKGAK--------GYRGPEGPQGPPGHQGPPG 590
             P G+ G+K        G  GP GP+G PG  GPPG
Sbjct: 690 GLP-GIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPG 725



 Score =  220 bits (561), Expect = 5e-57
 Identities = 138/348 (39%), Positives = 156/348 (44%), Gaps = 86/348 (24%)

Query: 329 GVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGD------------------------- 363
           G+ G KGE G+PGL G  G PGF G +GPPGP+G                          
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP 101

Query: 364 --------------------PGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGP- 402
                               PG  G KGE+G PG+ G  G  G  GP G  G  GEPG  
Sbjct: 102 GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSI 161

Query: 403 -----PGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGR- 456
                PG KG  G  G PG  G PG  G PG  GP G PG  GP G PG  GP+G+ G  
Sbjct: 162 IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLN 221

Query: 457 -EGPVGVPGDPGEAGPIGPKG-------------YRGDEGPPGSEGARGAPGPAGPPGDP 502
            +GP G  G+ G  GP GP G              +GD+G PG  G  G PG  GPPG P
Sbjct: 222 FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPP 281

Query: 503 -GLMGERGEDG-------PAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGD 554
            G  GE+GE G       P  +G  G PG PG PG+ G PG  G  G  G KGD G  G 
Sbjct: 282 GGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGP 341

Query: 555 PG------------DDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPG 590
           PG             +  +I   G+ G KG RG  G QGPPG  GPPG
Sbjct: 342 PGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG 389



 Score =  161 bits (408), Expect = 3e-39
 Identities = 103/251 (41%), Positives = 115/251 (45%), Gaps = 36/251 (14%)

Query: 377 GADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTP 436
           G   EA       P       G  G  GE+G  G EG+PG  G PG  G PG RG +G  
Sbjct: 21  GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80

Query: 437 GTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY------RGDEGPPGSEGAR 490
           G  GP G  G  GP G  G  G  G+PG PG  G  GP+G       +G+ G PGS G  
Sbjct: 81  GIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP 140

Query: 491 GAPGPAGPPGDPGLMGERGE------DGPAGN-GTEGFPGFPGYPGNRGAPGINGTKGYP 543
           G  GP GPPG PG+ GE G        GP GN G  G PG  G PG  G PG  G  G P
Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPP 200

Query: 544 GLKGDEGEAGDPGDDN----NDIAPRGVKGAKGYRGPEGP-------------------Q 580
           GL G  G  G PG       N   P+G KG +G +GP GP                   Q
Sbjct: 201 GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQ 260

Query: 581 GPPGHQGPPGP 591
           G PG +GPPGP
Sbjct: 261 GLPGDRGPPGP 271



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 27/62 (43%), Positives = 29/62 (46%)

Query: 253  QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312
            Q  +G PG  G PG  G  G PG  G  G  GDPG PG  G  G  G  G  G +G  G 
Sbjct: 1399 QGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGP 1458

Query: 313  RG 314
             G
Sbjct: 1459 PG 1460



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 30/75 (40%), Positives = 36/75 (48%), Gaps = 3/75 (4%)

Query: 256  RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
            +G PG +G  G  G  G PG PG  G    PG  G  G  G  G+ G+ G+RG  G  GP
Sbjct: 1393 KGLPGPQGPQGLPGPTGPPGDPGRNGL---PGFDGAGGRKGDPGLPGQPGTRGLDGPPGP 1449

Query: 316  KGYKGEKGKRGIDGV 330
             G +G  G  G   V
Sbjct: 1450 DGLQGPPGPPGTSSV 1464


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.139    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,680,757
Number of Sequences: 37866
Number of extensions: 3550455
Number of successful extensions: 121072
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 391
Number of HSP's successfully gapped in prelim test: 1064
Number of HSP's that attempted gapping in prelim test: 12580
Number of HSP's gapped (non-prelim): 13352
length of query: 1028
length of database: 18,247,518
effective HSP length: 112
effective length of query: 916
effective length of database: 14,006,526
effective search space: 12829977816
effective search space used: 12829977816
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press