Search of human proteins with 6912582

Search of human proteins with 6912582

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|6912582 penta-EF-hand domain containing 1 [Homo sapiens]
         (284 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6912582 penta-EF-hand domain containing 1 [Homo sapiens]           610   e-175
gi|7019485 programmed cell death 6 [Homo sapiens]                     135   4e-32
gi|4507207 sorcin isoform a [Homo sapiens]                            121   6e-28
gi|38679884 sorcin isoform b [Homo sapiens]                           115   6e-26
gi|6912388 grancalcin, EF-hand calcium binding protein [Homo sap...   112   4e-25
gi|4502565 calpain, small subunit 1 [Homo sapiens]                     88   1e-17
gi|51599151 calpain, small subunit 1 [Homo sapiens]                    88   1e-17
gi|14161692 calpain small subunit 2 [Homo sapiens]                     82   5e-16
gi|12408656 calpain 1, large subunit [Homo sapiens]                    77   1e-14
gi|215490104 calpain 11 [Homo sapiens]                                 77   2e-14
gi|47078247 calpain 3 isoform f [Homo sapiens]                         76   4e-14
gi|4557405 calpain 3 isoform a [Homo sapiens]                          76   4e-14
gi|27765072 calpain 3 isoform b [Homo sapiens]                         76   4e-14
gi|27765080 calpain 3 isoform e [Homo sapiens]                         76   4e-14
gi|27765078 calpain 3 isoform e [Homo sapiens]                         76   4e-14
gi|27765076 calpain 3 isoform d [Homo sapiens]                         76   4e-14
gi|27765074 calpain 3 isoform c [Homo sapiens]                         76   4e-14
gi|157389005 calpain 2 isoform 1 [Homo sapiens]                        75   7e-14
gi|225703100 calpain 2 isoform 2 [Homo sapiens]                        75   7e-14
gi|7705383 calpain 9 isoform 2 [Homo sapiens]                          74   2e-13
gi|5729758 calpain 9 isoform 1 [Homo sapiens]                          74   2e-13
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      73   2e-13
gi|4809279 annexin VII isoform 2 [Homo sapiens]                        71   9e-13
gi|4502111 annexin VII isoform 1 [Homo sapiens]                        71   9e-13
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      69   6e-12
gi|221554549 calpain 8 [Homo sapiens]                                  65   7e-11
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 64   2e-10
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]           63   3e-10
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                62   4e-10
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       62   6e-10

>gi|6912582 penta-EF-hand domain containing 1 [Homo sapiens]
          Length = 284

 Score =  610 bits (1572), Expect = e-175
 Identities = 284/284 (100%), Positives = 284/284 (100%)

Query: 1   MASYPYRQGCPGAAGQAPGAPPGSYYPGPPNSGGQYGSGLPPGGGYGGPAPGGPYGPPAG 60
           MASYPYRQGCPGAAGQAPGAPPGSYYPGPPNSGGQYGSGLPPGGGYGGPAPGGPYGPPAG
Sbjct: 1   MASYPYRQGCPGAAGQAPGAPPGSYYPGPPNSGGQYGSGLPPGGGYGGPAPGGPYGPPAG 60

Query: 61  GGPYGHPNPGMFPSGTPGGPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGGAPPNVDPEAY 120
           GGPYGHPNPGMFPSGTPGGPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGGAPPNVDPEAY
Sbjct: 61  GGPYGHPNPGMFPSGTPGGPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGGAPPNVDPEAY 120

Query: 121 SWFQSVDSDHSGYISMKELKQALVNCNWSSFNDETCLMMINMFDKTKSGRIDVYGFSALW 180
           SWFQSVDSDHSGYISMKELKQALVNCNWSSFNDETCLMMINMFDKTKSGRIDVYGFSALW
Sbjct: 121 SWFQSVDSDHSGYISMKELKQALVNCNWSSFNDETCLMMINMFDKTKSGRIDVYGFSALW 180

Query: 181 KFIQQWKNLFQQYDRDRSGSISYTELQQALSQMGYNLSPQFTQLLVSRYCPRSANPAMQL 240
           KFIQQWKNLFQQYDRDRSGSISYTELQQALSQMGYNLSPQFTQLLVSRYCPRSANPAMQL
Sbjct: 181 KFIQQWKNLFQQYDRDRSGSISYTELQQALSQMGYNLSPQFTQLLVSRYCPRSANPAMQL 240

Query: 241 DRFIQVCTQLQVLTEAFREKDTAVQGNIRLSFEDFVTMTASRML 284
           DRFIQVCTQLQVLTEAFREKDTAVQGNIRLSFEDFVTMTASRML
Sbjct: 241 DRFIQVCTQLQVLTEAFREKDTAVQGNIRLSFEDFVTMTASRML 284


>gi|7019485 programmed cell death 6 [Homo sapiens]
          Length = 191

 Score =  135 bits (340), Expect = 4e-32
 Identities = 74/175 (42%), Positives = 104/175 (59%), Gaps = 6/175 (3%)

Query: 109 GGAPPNVDPEAYSW--FQSVDSDHSGYISMKELKQALVNCNWSSFNDETCLMMINMFDKT 166
           G A P+   +++ W  FQ VD D SG IS  EL+QAL N  W+ FN  T   +I+MFD+ 
Sbjct: 19  GAALPD---QSFLWNVFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRE 75

Query: 167 KSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSISYTELQQALSQMGYNLSPQFTQLLV 226
               ++   F+ +WK+I  W+N+F+ YDRD SG I   EL+QALS  GY LS QF  +L+
Sbjct: 76  NKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILI 135

Query: 227 SRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKDTAVQGNIRLSFEDFVTMTAS 281
            ++  R     +  D FIQ C  LQ LT+ FR  DT   G I++S+E +++M  S
Sbjct: 136 RKF-DRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFS 189


>gi|4507207 sorcin isoform a [Homo sapiens]
          Length = 198

 Score =  121 bits (304), Expect = 6e-28
 Identities = 80/228 (35%), Positives = 113/228 (49%), Gaps = 34/228 (14%)

Query: 54  PYGPPAGGGPYGHPNPGMFPSGTPGGPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGGAPP 113
           P  P AGGG Y            PGG YGGA PGGP      +  G  Q  LYG   A  
Sbjct: 4   PGHPGAGGGYY------------PGG-YGGA-PGGP------AFPGQTQDPLYGYFAAVA 43

Query: 114 NVDPEAYSWFQSVDSDHSGYISMKELKQALVNCNWSSFNDETCLMMINMFDKTKSGRIDV 173
             D +       +D+D       + L Q+ +   +  FN ETC +M++M D+  SG +  
Sbjct: 44  GQDGQ-------IDADEL----QRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGF 92

Query: 174 YGFSALWKFIQQWKNLFQQYDRDRSGSISYTELQQALSQMGYNLSPQFTQLLVSRYCPRS 233
             F  LW  +  W+  F  +D DRSG++   ELQ+AL+ MG+ LSPQ    +  RY   S
Sbjct: 93  NEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRY---S 149

Query: 234 ANPAMQLDRFIQVCTQLQVLTEAFREKDTAVQGNIRLSFEDFVTMTAS 281
            N  +  D +I  C +L+ LT++FR +DTA QG +   ++DF+    S
Sbjct: 150 TNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVMS 197


>gi|38679884 sorcin isoform b [Homo sapiens]
          Length = 183

 Score =  115 bits (287), Expect = 6e-26
 Identities = 70/201 (34%), Positives = 103/201 (51%), Gaps = 21/201 (10%)

Query: 81  YGGAAPGGPYGQPPPSSYGAQQPGLYGQGGAPPNVDPEAYSWFQSVDSDHSGYISMKELK 140
           YGGA PGGP      +  G  Q  LYG   A    D +       +D+D       + L 
Sbjct: 3   YGGA-PGGP------AFPGQTQDPLYGYFAAVAGQDGQ-------IDADEL----QRCLT 44

Query: 141 QALVNCNWSSFNDETCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGS 200
           Q+ +   +  FN ETC +M++M D+  SG +    F  LW  +  W+  F  +D DRSG+
Sbjct: 45  QSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGT 104

Query: 201 ISYTELQQALSQMGYNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREK 260
           +   ELQ+AL+ MG+ LSPQ    +  RY   S N  +  D +I  C +L+ LT++FR +
Sbjct: 105 VDPQELQKALTTMGFRLSPQAVNSIAKRY---STNGKITFDDYIACCVKLRALTDSFRRR 161

Query: 261 DTAVQGNIRLSFEDFVTMTAS 281
           DTA QG +   ++DF+    S
Sbjct: 162 DTAQQGVVNFPYDDFIQCVMS 182


>gi|6912388 grancalcin, EF-hand calcium binding protein [Homo
           sapiens]
          Length = 217

 Score =  112 bits (280), Expect = 4e-25
 Identities = 69/216 (31%), Positives = 111/216 (51%), Gaps = 22/216 (10%)

Query: 78  GGPYGGAA---PGGPYGQPPPSSYGAQQPGLYGQGGAPP-------NVDPEAYSWFQSVD 127
           GG +G  +   PG   GQP P +     P +   G + P       +     Y++F +V 
Sbjct: 7   GGGFGNFSIQVPGMQMGQPVPET----GPAILLDGYSGPAYSDTYSSAGDSVYTYFSAV- 61

Query: 128 SDHSGYISMKELKQAL----VNCNWSSFNDETCLMMINMFDKTKSGRIDVYGFSALWKFI 183
           +   G +  +EL++ L    +N  +S F+ ETC +MI M D+  +G++    F  LW  +
Sbjct: 62  AGQDGEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAAL 121

Query: 184 QQWKNLFQQYDRDRSGSISYTELQQALSQMGYNLSPQFTQLLVSRYCPRSANPAMQLDRF 243
             WK  F   D+D SG++ + EL+QA+  MGY LSPQ    +V RY   S N  +  D +
Sbjct: 122 NAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRY---SKNGRIFFDDY 178

Query: 244 IQVCTQLQVLTEAFREKDTAVQGNIRLSFEDFVTMT 279
           +  C +L+ LT+ FR++D   QG+    ++DF+  T
Sbjct: 179 VACCVKLRALTDFFRKRDHLQQGSANFIYDDFLQGT 214


>gi|4502565 calpain, small subunit 1 [Homo sapiens]
          Length = 268

 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 71/258 (27%), Positives = 110/258 (42%), Gaps = 26/258 (10%)

Query: 43  GGGYGGPAPGGPYGPPAGG---GPYGHPNPGMFPSGTPGGPYGGAAPGGPYGQPPPSSYG 99
           GGG GG   GG  G   GG   G  G    G    G  GG  GG A     G     S  
Sbjct: 13  GGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGGVISAISEA 72

Query: 100 AQQPGLYGQGGAPPNV--------DPEAYSWFQSVDSDHSG---YISMKELKQAL----- 143
           A Q   Y     PP          + E    F+ + +  +G    +S  EL   L     
Sbjct: 73  AAQ---YNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVT 129

Query: 144 --VNCNWSSFNDETCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSI 201
              +     F  +TC  M+ + D   +G++    F  LW  I++W+ +++Q+D DRSG+I
Sbjct: 130 RHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTI 189

Query: 202 SYTELQQALSQMGYNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKD 261
             +EL  A    G++L+     +++ RY   S N  M  D FI    +L  +  AF+  D
Sbjct: 190 CSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGN--MDFDNFISCLVRLDAMFRAFKSLD 247

Query: 262 TAVQGNIRLSFEDFVTMT 279
               G I+++ ++++ +T
Sbjct: 248 KDGTGQIQVNIQEWLQLT 265


>gi|51599151 calpain, small subunit 1 [Homo sapiens]
          Length = 268

 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 71/258 (27%), Positives = 110/258 (42%), Gaps = 26/258 (10%)

Query: 43  GGGYGGPAPGGPYGPPAGG---GPYGHPNPGMFPSGTPGGPYGGAAPGGPYGQPPPSSYG 99
           GGG GG   GG  G   GG   G  G    G    G  GG  GG A     G     S  
Sbjct: 13  GGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGGVISAISEA 72

Query: 100 AQQPGLYGQGGAPPNV--------DPEAYSWFQSVDSDHSG---YISMKELKQAL----- 143
           A Q   Y     PP          + E    F+ + +  +G    +S  EL   L     
Sbjct: 73  AAQ---YNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVT 129

Query: 144 --VNCNWSSFNDETCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSI 201
              +     F  +TC  M+ + D   +G++    F  LW  I++W+ +++Q+D DRSG+I
Sbjct: 130 RHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTI 189

Query: 202 SYTELQQALSQMGYNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKD 261
             +EL  A    G++L+     +++ RY   S N  M  D FI    +L  +  AF+  D
Sbjct: 190 CSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGN--MDFDNFISCLVRLDAMFRAFKSLD 247

Query: 262 TAVQGNIRLSFEDFVTMT 279
               G I+++ ++++ +T
Sbjct: 248 KDGTGQIQVNIQEWLQLT 265


>gi|14161692 calpain small subunit 2 [Homo sapiens]
          Length = 248

 Score = 82.0 bits (201), Expect = 5e-16
 Identities = 39/129 (30%), Positives = 74/129 (57%), Gaps = 2/129 (1%)

Query: 151 FNDETCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSISYTELQQAL 210
           F+ +TC  ++++ D   +G++    F  LW  I++W+ +++QYDRD SGS+  ++L+ AL
Sbjct: 119 FSLDTCRSIVSVMDSDTTGKLGFEEFKYLWNNIKKWQCVYKQYDRDHSGSLGSSQLRGAL 178

Query: 211 SQMGYNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKDTAVQGNIRL 270
              G+ L+ Q  Q++V RY     +  M  + FI    +L  +  AF+  D    G I++
Sbjct: 179 QAAGFQLNEQLYQMIVRRYANEDGD--MDFNNFISCLVRLDAMFRAFKSLDRDRDGLIQV 236

Query: 271 SFEDFVTMT 279
           S ++++ +T
Sbjct: 237 SIKEWLQLT 245



 Score = 32.0 bits (71), Expect = 0.63
 Identities = 20/79 (25%), Positives = 36/79 (45%), Gaps = 2/79 (2%)

Query: 123 FQSVDSDHSGYISMKELKQALVNCNWSSFNDETCLMMINMFDKTKSGRIDVYGFSALWKF 182
           ++  D DHSG +   +L+ AL    +   N++   M++  +   + G +D   F +    
Sbjct: 158 YKQYDRDHSGSLGSSQLRGALQAAGF-QLNEQLYQMIVRRY-ANEDGDMDFNNFISCLVR 215

Query: 183 IQQWKNLFQQYDRDRSGSI 201
           +      F+  DRDR G I
Sbjct: 216 LDAMFRAFKSLDRDRDGLI 234


>gi|12408656 calpain 1, large subunit [Homo sapiens]
          Length = 714

 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 40/153 (26%), Positives = 84/153 (54%), Gaps = 9/153 (5%)

Query: 134 ISMKELKQAL-------VNCNWSSFNDETCLMMINMFDKTKSGRIDVYGFSALWKFIQQW 186
           IS+KEL+  L        +     F+ E+C  M+N+ D+  +G++ +  F+ LW  I+ +
Sbjct: 561 ISVKELRTILNRIISKHKDLRTKGFSLESCRSMVNLMDRDGNGKLGLVEFNILWNRIRNY 620

Query: 187 KNLFQQYDRDRSGSISYTELQQALSQMGYNLSPQFTQLLVSRYCPRSANPAMQLDRFIQV 246
            ++F+++D D+SGS+S  E++ A+   G+ L+ +  +L+++RY     + A+  D F+  
Sbjct: 621 LSIFRKFDLDKSGSMSAYEMRMAIESAGFKLNKKLYELIITRY--SEPDLAVDFDNFVCC 678

Query: 247 CTQLQVLTEAFREKDTAVQGNIRLSFEDFVTMT 279
             +L+ +   F+  DT + G +      ++ +T
Sbjct: 679 LVRLETMFRFFKTLDTDLDGVVTFDLFKWLQLT 711


>gi|215490104 calpain 11 [Homo sapiens]
          Length = 739

 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 40/129 (31%), Positives = 72/129 (55%), Gaps = 2/129 (1%)

Query: 151 FNDETCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSISYTELQQAL 210
           F  + C  MIN+ DK  SG++ +  F  LWK +++W ++F++ D+D SG+++  E++  +
Sbjct: 610 FGLDACRCMINLMDKDGSGKLGLLEFKILWKKLKKWMDIFRECDQDHSGTLNSYEMRLVI 669

Query: 211 SQMGYNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKDTAVQGNIRL 270
            + G  L+ +  Q+LV+RY     +  +  D FI    +L+ +   F   D    G+I L
Sbjct: 670 EKAGIKLNNKVMQVLVARYA--DDDLIIDFDSFISCFLRLKTMFTFFLTMDPKNTGHICL 727

Query: 271 SFEDFVTMT 279
           S E ++ MT
Sbjct: 728 SLEQWLQMT 736


>gi|47078247 calpain 3 isoform f [Homo sapiens]
          Length = 728

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 39/129 (30%), Positives = 72/129 (55%), Gaps = 2/129 (1%)

Query: 151 FNDETCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSISYTELQQAL 210
           F  E+C  MI + D   SG++++  F  LW  I+ W+ +F+ YD D+SG+I+  E++ A+
Sbjct: 599 FTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAV 658

Query: 211 SQMGYNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKDTAVQGNIRL 270
           +  G++L+ Q   ++  RY  +  N  +  D FI    +L+ +  AF   D    G I+L
Sbjct: 659 NDAGFHLNNQLYDIITMRYADKHMN--IDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKL 716

Query: 271 SFEDFVTMT 279
           +  +++ +T
Sbjct: 717 NVLEWLQLT 725


>gi|4557405 calpain 3 isoform a [Homo sapiens]
          Length = 821

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 39/129 (30%), Positives = 72/129 (55%), Gaps = 2/129 (1%)

Query: 151 FNDETCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSISYTELQQAL 210
           F  E+C  MI + D   SG++++  F  LW  I+ W+ +F+ YD D+SG+I+  E++ A+
Sbjct: 692 FTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAV 751

Query: 211 SQMGYNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKDTAVQGNIRL 270
           +  G++L+ Q   ++  RY  +  N  +  D FI    +L+ +  AF   D    G I+L
Sbjct: 752 NDAGFHLNNQLYDIITMRYADKHMN--IDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKL 809

Query: 271 SFEDFVTMT 279
           +  +++ +T
Sbjct: 810 NVLEWLQLT 818


>gi|27765072 calpain 3 isoform b [Homo sapiens]
          Length = 815

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 39/129 (30%), Positives = 72/129 (55%), Gaps = 2/129 (1%)

Query: 151 FNDETCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSISYTELQQAL 210
           F  E+C  MI + D   SG++++  F  LW  I+ W+ +F+ YD D+SG+I+  E++ A+
Sbjct: 686 FTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAV 745

Query: 211 SQMGYNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKDTAVQGNIRL 270
           +  G++L+ Q   ++  RY  +  N  +  D FI    +L+ +  AF   D    G I+L
Sbjct: 746 NDAGFHLNNQLYDIITMRYADKHMN--IDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKL 803

Query: 271 SFEDFVTMT 279
           +  +++ +T
Sbjct: 804 NVLEWLQLT 812


>gi|27765080 calpain 3 isoform e [Homo sapiens]
          Length = 156

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 39/129 (30%), Positives = 72/129 (55%), Gaps = 2/129 (1%)

Query: 151 FNDETCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSISYTELQQAL 210
           F  E+C  MI + D   SG++++  F  LW  I+ W+ +F+ YD D+SG+I+  E++ A+
Sbjct: 27  FTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAV 86

Query: 211 SQMGYNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKDTAVQGNIRL 270
           +  G++L+ Q   ++  RY  +  N  +  D FI    +L+ +  AF   D    G I+L
Sbjct: 87  NDAGFHLNNQLYDIITMRYADKHMN--IDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKL 144

Query: 271 SFEDFVTMT 279
           +  +++ +T
Sbjct: 145 NVLEWLQLT 153


>gi|27765078 calpain 3 isoform e [Homo sapiens]
          Length = 156

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 39/129 (30%), Positives = 72/129 (55%), Gaps = 2/129 (1%)

Query: 151 FNDETCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSISYTELQQAL 210
           F  E+C  MI + D   SG++++  F  LW  I+ W+ +F+ YD D+SG+I+  E++ A+
Sbjct: 27  FTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAV 86

Query: 211 SQMGYNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKDTAVQGNIRL 270
           +  G++L+ Q   ++  RY  +  N  +  D FI    +L+ +  AF   D    G I+L
Sbjct: 87  NDAGFHLNNQLYDIITMRYADKHMN--IDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKL 144

Query: 271 SFEDFVTMT 279
           +  +++ +T
Sbjct: 145 NVLEWLQLT 153


>gi|27765076 calpain 3 isoform d [Homo sapiens]
          Length = 309

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 39/129 (30%), Positives = 72/129 (55%), Gaps = 2/129 (1%)

Query: 151 FNDETCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSISYTELQQAL 210
           F  E+C  MI + D   SG++++  F  LW  I+ W+ +F+ YD D+SG+I+  E++ A+
Sbjct: 180 FTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAV 239

Query: 211 SQMGYNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKDTAVQGNIRL 270
           +  G++L+ Q   ++  RY  +  N  +  D FI    +L+ +  AF   D    G I+L
Sbjct: 240 NDAGFHLNNQLYDIITMRYADKHMN--IDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKL 297

Query: 271 SFEDFVTMT 279
           +  +++ +T
Sbjct: 298 NVLEWLQLT 306


>gi|27765074 calpain 3 isoform c [Homo sapiens]
          Length = 729

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 39/129 (30%), Positives = 72/129 (55%), Gaps = 2/129 (1%)

Query: 151 FNDETCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSISYTELQQAL 210
           F  E+C  MI + D   SG++++  F  LW  I+ W+ +F+ YD D+SG+I+  E++ A+
Sbjct: 600 FTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAV 659

Query: 211 SQMGYNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKDTAVQGNIRL 270
           +  G++L+ Q   ++  RY  +  N  +  D FI    +L+ +  AF   D    G I+L
Sbjct: 660 NDAGFHLNNQLYDIITMRYADKHMN--IDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKL 717

Query: 271 SFEDFVTMT 279
           +  +++ +T
Sbjct: 718 NVLEWLQLT 726


>gi|157389005 calpain 2 isoform 1 [Homo sapiens]
          Length = 700

 Score = 75.1 bits (183), Expect = 7e-14
 Identities = 36/120 (30%), Positives = 71/120 (59%), Gaps = 2/120 (1%)

Query: 151 FNDETCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSISYTELQQAL 210
           F+ ETC +M++M D   SG++ +  F  LW  IQ+++ ++++ D DRSG+++  E+++AL
Sbjct: 572 FSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKAL 631

Query: 211 SQMGYNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKDTAVQGNIRL 270
            + G+ +  Q  Q++V+R+        +  D F++   +L+ L + F++ D    G I L
Sbjct: 632 EEAGFKMPCQLHQVIVARFADDQL--IIDFDNFVRCLVRLETLFKIFKQLDPENTGTIEL 689


>gi|225703100 calpain 2 isoform 2 [Homo sapiens]
          Length = 622

 Score = 75.1 bits (183), Expect = 7e-14
 Identities = 36/120 (30%), Positives = 71/120 (59%), Gaps = 2/120 (1%)

Query: 151 FNDETCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSISYTELQQAL 210
           F+ ETC +M++M D   SG++ +  F  LW  IQ+++ ++++ D DRSG+++  E+++AL
Sbjct: 494 FSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKAL 553

Query: 211 SQMGYNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKDTAVQGNIRL 270
            + G+ +  Q  Q++V+R+        +  D F++   +L+ L + F++ D    G I L
Sbjct: 554 EEAGFKMPCQLHQVIVARFADDQL--IIDFDNFVRCLVRLETLFKIFKQLDPENTGTIEL 611


>gi|7705383 calpain 9 isoform 2 [Homo sapiens]
          Length = 664

 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 37/125 (29%), Positives = 67/125 (53%), Gaps = 2/125 (1%)

Query: 155 TCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSISYTELQQALSQMG 214
           +C  +I++ D + +G+++   F   W  ++QW NLF ++D D+SG++S  EL+ AL   G
Sbjct: 539 SCKNIISLMDTSGNGKLEFDEFKVFWDKLKQWINLFLRFDADKSGTMSTYELRTALKAAG 598

Query: 215 YNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKDTAVQGNIRLSFED 274
           + LS    QL+V RY        +  D F+    +L+  +  F+   T  +  I L+  +
Sbjct: 599 FQLSSHLLQLIVLRYADEELQ--LDFDDFLNCLVRLENASRVFQALSTKNKEFIHLNINE 656

Query: 275 FVTMT 279
           F+ +T
Sbjct: 657 FIHLT 661


>gi|5729758 calpain 9 isoform 1 [Homo sapiens]
          Length = 690

 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 37/125 (29%), Positives = 67/125 (53%), Gaps = 2/125 (1%)

Query: 155 TCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSISYTELQQALSQMG 214
           +C  +I++ D + +G+++   F   W  ++QW NLF ++D D+SG++S  EL+ AL   G
Sbjct: 565 SCKNIISLMDTSGNGKLEFDEFKVFWDKLKQWINLFLRFDADKSGTMSTYELRTALKAAG 624

Query: 215 YNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKDTAVQGNIRLSFED 274
           + LS    QL+V RY        +  D F+    +L+  +  F+   T  +  I L+  +
Sbjct: 625 FQLSSHLLQLIVLRYADEELQ--LDFDDFLNCLVRLENASRVFQALSTKNKEFIHLNINE 682

Query: 275 FVTMT 279
           F+ +T
Sbjct: 683 FIHLT 687


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 53/125 (42%), Positives = 57/125 (45%), Gaps = 17/125 (13%)

Query: 2   ASYPYRQGCPGAAG-QAPGAPPGSYYPGPPNSGGQYGSGLPPG------GGYGGPAPGGP 54
           A  P R G PG  G   P  PPG   PGPP  GG +   L  G      GG   P P GP
Sbjct: 126 AGPPGRDGIPGQPGLPGPPGPPGP--PGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGP 183

Query: 55  YGPPAGGGPYGHPNPGMF--PSGTPGGPYGGAAPGGPYGQP-PPSSYG----AQQPGLYG 107
            GP    GP G P P  F  P G PG P G + P GP G P PP   G    A +PG  G
Sbjct: 184 SGPRGLPGPPGAPGPQGFQGPPGEPGEP-GASGPMGPRGPPGPPGKNGDDGEAGKPGRPG 242

Query: 108 QGGAP 112
           + G P
Sbjct: 243 ERGPP 247



 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 49/132 (37%), Positives = 56/132 (42%), Gaps = 25/132 (18%)

Query: 8   QGCPGAAGQAPGAPPGSYYPGPPNSGGQYGSGLPPG-----GGYGGPAPGGPYGPPAGGG 62
           +G PG  G+ PG P  + + GPP + GQ G+   PG     G  G P P GP GPP   G
Sbjct: 796 RGAPGDRGE-PGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIG 854

Query: 63  PYGHPN----------PGM--FPSGT----PGGPYGGAAPGGPYGQPPPSSYGAQQP-GL 105
             G P           PG   FP       P GP G A P GP G  P    G + P G 
Sbjct: 855 NVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPG--PAGKEGGKGPRGE 912

Query: 106 YGQGGAPPNVDP 117
            G  G P  V P
Sbjct: 913 TGPAGRPGEVGP 924



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 51/147 (34%), Positives = 54/147 (36%), Gaps = 40/147 (27%)

Query: 5    PYRQGCPGAAGQ-----------APGAPPGSYYPGPPNSGGQYGSGLPPG-----GGYGG 48
            P R G PGA G            APGAP      GP    G  G   P G     G  G 
Sbjct: 1024 PGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGA 1083

Query: 49   PAPGGPYGPPAGGGPYGHPN----------------PGMFPSGTPG--GPYGGAAPGGPY 90
              P GP GP    G  G                   PG  P G+PG  GP G + P GP 
Sbjct: 1084 RGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPG--PPGSPGEQGPSGASGPAGPR 1141

Query: 91   GQPPPSSYGAQQPGLYGQGGAPPNVDP 117
            G  PP S GA  PG  G  G P  + P
Sbjct: 1142 G--PPGSAGA--PGKDGLNGLPGPIGP 1164



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 48/126 (38%), Positives = 53/126 (42%), Gaps = 8/126 (6%)

Query: 2   ASYPYRQGCPGAAGQA--PGAPPGSYYPGPPNSGGQYGSGLPPGGGYGGPAPGGPYGPPA 59
           A  P   G PGAAG+   PG    +  PGPP   G+ G G  P G  G     G  GPP 
Sbjct: 868 AGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEG-GKGPRGETGPAGRPGEVGPPG 926

Query: 60  GGGPYGHP-NPGM-FPSGTPG--GPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGGAPPNV 115
             GP G   +PG   P+G PG  GP G A   G  G P         PGL G  G P   
Sbjct: 927 PPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERG-FPGLPGPSGEPGKQ 985

Query: 116 DPEAYS 121
            P   S
Sbjct: 986 GPSGAS 991



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 44/121 (36%), Positives = 49/121 (40%), Gaps = 22/121 (18%)

Query: 5   PYRQGCPGAAGQA----PGAPPGSYYP-GPPNSGGQYG----SGLPPGGGY----GGPAP 51
           P  +G PGA G A    P    GS  P GP  S G+ G    +GLP   G     G P P
Sbjct: 490 PGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGP 549

Query: 52  GGPYGPPAGGGPYGHPNPGMFPSGTPGGPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGGA 111
            G  GPP   G  G P         P GP G     G  G P P    A +PG  G+ G 
Sbjct: 550 DGKTGPPGPAGQDGRPG--------PPGPPGARGQAGVMGFPGPKG-AAGEPGKAGERGV 600

Query: 112 P 112
           P
Sbjct: 601 P 601



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 49/147 (33%), Positives = 56/147 (38%), Gaps = 38/147 (25%)

Query: 7   RQGCPGAAGQ----APGAPPGSY-------YPGP------PNSGGQYGSGLPPG------ 43
           + G PG AGQ     P  PPG+        +PGP      P   G+ G   PPG      
Sbjct: 552 KTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAG 611

Query: 44  -----GGYGGPAPGGPYGPPAGGGPYGHPN----PGMFPSGTPG--GPYGGAAPGGPYGQ 92
                G  G P P GP G     GP G P     PG  P+G PG  G  G     G  G 
Sbjct: 612 KDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPG--PAGPPGEAGKPGEQGVPGDLGA 669

Query: 93  PPPSSYGAQQ--PGLYGQGGAPPNVDP 117
           P PS    ++  PG  G  G P    P
Sbjct: 670 PGPSGARGERGFPGERGVQGPPGPAGP 696



 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 39/90 (43%), Positives = 41/90 (45%), Gaps = 4/90 (4%)

Query: 5    PYRQGCPGAAGQA-PGAPPGSY-YPGPPNSGGQYGSGLPPG--GGYGGPAPGGPYGPPAG 60
            P  QG  GA+G A P  PPGS   PG     G  G   PPG  G  G   P GP GPP  
Sbjct: 1126 PGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGP 1185

Query: 61   GGPYGHPNPGMFPSGTPGGPYGGAAPGGPY 90
             GP G P+ G   S  P  P   A  GG Y
Sbjct: 1186 PGPPGPPSAGFDFSFLPQPPQEKAHDGGRY 1215



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 46/141 (32%), Positives = 53/141 (37%), Gaps = 29/141 (20%)

Query: 2   ASYPYRQGCPGAAGQ--APGAPPGSYYPGPPNSGGQYGSGLPPG---------------- 43
           A  P   G PGA G   APG      +PG     G  G G PPG                
Sbjct: 385 AGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGD 444

Query: 44  -GGYGGPAPGGPYGPPAGGGPYG----HPNPGMFPSGTPGGPYGGAAPGGPYGQPPPSSY 98
            G  G P P G  GPP   G  G       PG  P+G PG P      GGP  +  P + 
Sbjct: 445 TGAKGEPGPVGVQGPPGPAGEEGKRGARGEPG--PTGLPGPP---GERGGPGSRGFPGAD 499

Query: 99  GAQQP-GLYGQGGAPPNVDPE 118
           G   P G  G+ G+P    P+
Sbjct: 500 GVAGPKGPAGERGSPGPAGPK 520



 Score = 51.6 bits (122), Expect = 8e-07
 Identities = 45/127 (35%), Positives = 49/127 (38%), Gaps = 13/127 (10%)

Query: 2    ASYPYRQGCPGAAGQA-----PGAPPGSYYPGPPNSGGQYGSGLPPGGGYGGPAPGGPYG 56
            A  P   G  G AGQ      PG      +PG P   G+ G    P G  G   P GP G
Sbjct: 943  AGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGK-QGPSGASGERGPPGPMG 1001

Query: 57   PPAGGGPYGHPNPGMFPSGTPGGPYGGAAPG--GPYGQPPPSSYGAQQPGLYGQGGAPPN 114
            PP   GP G       P G  G P    +PG  G  G+  P    A  PG  G  GAP  
Sbjct: 1002 PPGLAGPPGESGREGAP-GAEGSPGRDGSPGAKGDRGETGP----AGPPGAPGAPGAPGP 1056

Query: 115  VDPEAYS 121
            V P   S
Sbjct: 1057 VGPAGKS 1063



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 48/132 (36%), Positives = 50/132 (37%), Gaps = 31/132 (23%)

Query: 9   GCPGAAGQA-PGAPPGSYYPGPPNSGGQYGSGLPPG--GGYGGPAPGGPYGPPAGGGPYG 65
           G  G AG A P   PGS  PG   + GQ G    PG  G  G P P G  G     G  G
Sbjct: 275 GAKGDAGPAGPKGEPGS--PGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAG 332

Query: 66  HPNPGMFPSGTPG-----GPYGGAAPGGPYGQP----------PPSSYGAQ--------- 101
            P P   P+G PG     G  G A P GP G            PP   GA          
Sbjct: 333 PPGP-TGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGAD 391

Query: 102 -QPGLYGQGGAP 112
            QPG  G  GAP
Sbjct: 392 GQPGAKGANGAP 403



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 35/85 (41%), Positives = 36/85 (42%), Gaps = 21/85 (24%)

Query: 27   PGPPNSGGQYGSGLPPGGGYGGPAPGGPYGPPAGGGPYGHPN----PGMFPSGTPG---- 78
            PGPP S G+ G    P G  G   P GP GPP   G  G       PG  P G PG    
Sbjct: 1120 PGPPGSPGEQG----PSGASG---PAGPRGPPGSAGAPGKDGLNGLPG--PIGPPGPRGR 1170

Query: 79   ----GPYGGAAPGGPYGQPPPSSYG 99
                GP G   P GP G P P S G
Sbjct: 1171 TGDAGPVGPPGPPGPPGPPGPPSAG 1195



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 42/113 (37%), Positives = 46/113 (40%), Gaps = 16/113 (14%)

Query: 8   QGCPGAA---GQA-PGAPPGSYYPGPPNSGGQYGSGLPPGGGYGGPAPGGPYGPPAGGGP 63
           + CPGA    G+  P  P GS  P    + G  G    P G  G   P GP GPP   G 
Sbjct: 79  KNCPGAEVPEGECCPVCPDGSESPTDQETTGVEG----PKGDTGPRGPRGPAGPPGRDGI 134

Query: 64  YGHPN-PGMFPSGTPGGP-----YGGAAPGGPYGQPPPSSYGAQQPGLYGQGG 110
            G P  PG  P G PG P      G  AP   YG    S+ G   PG  G  G
Sbjct: 135 PGQPGLPG--PPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSG 185



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 42/114 (36%), Positives = 44/114 (38%), Gaps = 17/114 (14%)

Query: 5   PYRQGCPGAAGQAPGAPPGSYYPGPPNSGGQYGSGLPPG--GGYGGPAPGGPYGPPAGGG 62
           P + G  G  G  P  PPG    G P   G+ G   P G  G  G P   G  GPP   G
Sbjct: 757 PGKDGVRGLTG--PIGPPGP--AGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAG 812

Query: 63  PYGHPNPGMFP--SGTPG--GPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGGAP 112
             G P     P   G PG  G  G A P GP G   P       PG  G  GAP
Sbjct: 813 FAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGP-------PGPIGNVGAP 859



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 45/131 (34%), Positives = 50/131 (38%), Gaps = 25/131 (19%)

Query: 9   GCPGAAGQ----APGAPPGSYYPGPPNSGGQYGSGLP-----PGGGYGGPAPGGPYGPPA 59
           G  GAAG      P  PPG  +PG   + G+ G   P     P G  G P P GP G   
Sbjct: 326 GATGAAGPPGPTGPAGPPG--FPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAG 383

Query: 60  -GGGPYGHPNPG-MFPSGTPG-----------GPYGGAAPGGPYGQPPPSSYGAQQPGLY 106
             G P     PG    +G PG           GP G   PGGP G P  +S     PG  
Sbjct: 384 PAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPG-PKGNSGEPGAPGSK 442

Query: 107 GQGGAPPNVDP 117
           G  GA     P
Sbjct: 443 GDTGAKGEPGP 453



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 45/128 (35%), Positives = 50/128 (39%), Gaps = 37/128 (28%)

Query: 8    QGCPGAAGQAPGAPPGSYYP-------GPPNSGGQYGSGLPPG--------GGYGGP--- 49
            +G PG  G  P   PG   P       GPP   G  G   PPG        G  G P   
Sbjct: 970  RGFPGLPG--PSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRD 1027

Query: 50   -APG--------GPYGPPAGGGPYGHPNPGMFPSGTPG-----GPYGGAAPGGPYGQPPP 95
             +PG        GP GPP   G  G P P + P+G  G     GP G A P GP G   P
Sbjct: 1028 GSPGAKGDRGETGPAGPPGAPGAPGAPGP-VGPAGKSGDRGETGPAGPAGPVGPVGARGP 1086

Query: 96   SSYGAQQP 103
            +  G Q P
Sbjct: 1087 A--GPQGP 1092



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 46/124 (37%), Positives = 49/124 (39%), Gaps = 16/124 (12%)

Query: 2   ASYPYRQGCPGAAGQA-PGAPPGSY-------YPGPPNSGGQYGSGLPPGGGYGGPAPGG 53
           A  P   G  GA G+A P  P GS         PGPP   G  G    PG   G P   G
Sbjct: 340 AGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGAD-GQPGAKG 398

Query: 54  PYGPPAGGGPYGHPNPGMFPSGTPGGPYGGAAPGGPYGQP-PPSSYG----AQQPGLYGQ 108
             G P   G  G P     PSG P GP G   P G  G+P  P S G      +PG  G 
Sbjct: 399 ANGAPGIAGAPGFPG-ARGPSG-PQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGV 456

Query: 109 GGAP 112
            G P
Sbjct: 457 QGPP 460



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 44/133 (33%), Positives = 50/133 (37%), Gaps = 23/133 (17%)

Query: 3   SYPYRQGCPGAAGQAPGAPPGSYYPGPPNSGGQYGSGLPPGGGYGGPAPGGPYGPPAGGG 62
           S P   G  G  G  PG PPG+  PGP    G  G    PG   G   P GP GPP   G
Sbjct: 176 SVPGPMGPSGPRG-LPG-PPGA--PGPQGFQGPPGEPGEPGAS-GPMGPRGPPGPPGKNG 230

Query: 63  PYGHP-NPGMFPSGTPGGPYGGAAPGGPYGQPPPSSY-------GAQ----------QPG 104
             G    PG      P GP G     G  G P    +       GA+          +PG
Sbjct: 231 DDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPG 290

Query: 105 LYGQGGAPPNVDP 117
             G+ GAP  + P
Sbjct: 291 SPGENGAPGQMGP 303



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 41/127 (32%), Positives = 47/127 (37%), Gaps = 25/127 (19%)

Query: 8   QGCPGAAGQAPGAPPGSYYPGPPNSGGQYGSGLPPG-----GGYGGPAPGGPYGPPAGGG 62
           +G PG AG  PG      + G   + G  G   P G     G  G P   GP G P   G
Sbjct: 253 RGLPGTAG-LPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERG 311

Query: 63  PYGHPNP-------GMFPSGTPGGPYGGAAPGGPYG----------QPPPSSYGAQQPGL 105
             G P P       G   +  P GP G A P G  G          Q P  S G Q  G+
Sbjct: 312 RPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQ--GV 369

Query: 106 YGQGGAP 112
            G+ G P
Sbjct: 370 RGEPGPP 376



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 45/137 (32%), Positives = 49/137 (35%), Gaps = 34/137 (24%)

Query: 2   ASYPYRQGCPGAAGQAPGAPPGSY----YPG------PPNSGGQYGSGLPPG-----GGY 46
           A  P  QG PG  G APG P G+     +PG      PP   G  G+   PG     G  
Sbjct: 655 AGKPGEQGVPGDLG-APG-PSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDA 712

Query: 47  GGPAPGGPYGPPAGGGPYGHPNPGMFPSGTPGGPYGGAAPGGPYGQP------------- 93
           G P   G  G P   G  G       P   P G  G A P G  G P             
Sbjct: 713 GAPGAPGSQGAPGLQGMPGERGAAGLPG--PKGDRGDAGPKGADGSPGKDGVRGLTGPIG 770

Query: 94  PPSSYGAQQPGLYGQGG 110
           PP   GA  PG  G+ G
Sbjct: 771 PPGPAGA--PGDKGESG 785


>gi|4809279 annexin VII isoform 2 [Homo sapiens]
          Length = 488

 Score = 71.2 bits (173), Expect = 9e-13
 Identities = 56/131 (42%), Positives = 57/131 (43%), Gaps = 20/131 (15%)

Query: 4   YPYRQGCPGAAGQAPGAPPGSYYP----GPPNSGGQY----GSGLPPGGGYGGPAPGGPY 55
           YP   G P  AGQ    PP   YP     PP  GG Y     SG P  GGY  PAPG   
Sbjct: 11  YPPFPGYP-PAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGY--PAPG--- 64

Query: 56  GPPAGGGPYGHPNPGMFPS--GTPGGPYGGAAPGGP----YGQPPPSSYGAQQPGLYGQG 109
           G PA GG  G P PG  PS  G P G   G  PGG     Y QPP  SYG     +   G
Sbjct: 65  GYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPG 124

Query: 110 GAPPNVDPEAY 120
           G P    P  Y
Sbjct: 125 GFPGGQMPSQY 135



 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 39/91 (42%), Positives = 43/91 (47%), Gaps = 10/91 (10%)

Query: 9   GCPGAAGQ-APGAPPG-SYYPGPPNSGGQYG-SGLPPGGGYGGPAPGGPYG----PPA-- 59
           G PGA G  APG  P    YPG P  GG     G+PPG G+G P  G  +     PP+  
Sbjct: 53  GYPGAGGYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQS 112

Query: 60  -GGGPYGHPNPGMFPSGTPGGPYGGAAPGGP 89
            GGGP   P PG FP G     Y G  P  P
Sbjct: 113 YGGGPAQVPLPGGFPGGQMPSQYPGGQPTYP 143



 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 40/106 (37%), Positives = 45/106 (42%), Gaps = 21/106 (19%)

Query: 26  YPGPPNSGGQYGSGLPPGGGYGGPAPGGPYG-----PPAGGGPY------------GHPN 68
           YPG P +G     G PP G      P G Y      PP GGG Y            G+P 
Sbjct: 3   YPGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPA 62

Query: 69  PGMFPS--GTPGGPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGGAP 112
           PG +P+  G PG P  G AP  P G PP   +G   PG  G  G P
Sbjct: 63  PGGYPAPGGYPGAPQPGGAPSYP-GVPPGQGFGV-PPGGAGFSGYP 106


>gi|4502111 annexin VII isoform 1 [Homo sapiens]
          Length = 466

 Score = 71.2 bits (173), Expect = 9e-13
 Identities = 56/131 (42%), Positives = 57/131 (43%), Gaps = 20/131 (15%)

Query: 4   YPYRQGCPGAAGQAPGAPPGSYYP----GPPNSGGQY----GSGLPPGGGYGGPAPGGPY 55
           YP   G P  AGQ    PP   YP     PP  GG Y     SG P  GGY  PAPG   
Sbjct: 11  YPPFPGYP-PAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGY--PAPG--- 64

Query: 56  GPPAGGGPYGHPNPGMFPS--GTPGGPYGGAAPGGP----YGQPPPSSYGAQQPGLYGQG 109
           G PA GG  G P PG  PS  G P G   G  PGG     Y QPP  SYG     +   G
Sbjct: 65  GYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPG 124

Query: 110 GAPPNVDPEAY 120
           G P    P  Y
Sbjct: 125 GFPGGQMPSQY 135



 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 39/91 (42%), Positives = 43/91 (47%), Gaps = 10/91 (10%)

Query: 9   GCPGAAGQ-APGAPPG-SYYPGPPNSGGQYG-SGLPPGGGYGGPAPGGPYG----PPA-- 59
           G PGA G  APG  P    YPG P  GG     G+PPG G+G P  G  +     PP+  
Sbjct: 53  GYPGAGGYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQS 112

Query: 60  -GGGPYGHPNPGMFPSGTPGGPYGGAAPGGP 89
            GGGP   P PG FP G     Y G  P  P
Sbjct: 113 YGGGPAQVPLPGGFPGGQMPSQYPGGQPTYP 143



 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 40/106 (37%), Positives = 45/106 (42%), Gaps = 21/106 (19%)

Query: 26  YPGPPNSGGQYGSGLPPGGGYGGPAPGGPYG-----PPAGGGPY------------GHPN 68
           YPG P +G     G PP G      P G Y      PP GGG Y            G+P 
Sbjct: 3   YPGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPA 62

Query: 69  PGMFPS--GTPGGPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGGAP 112
           PG +P+  G PG P  G AP  P G PP   +G   PG  G  G P
Sbjct: 63  PGGYPAPGGYPGAPQPGGAPSYP-GVPPGQGFGV-PPGGAGFSGYP 106


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 68.6 bits (166), Expect = 6e-12
 Identities = 52/133 (39%), Positives = 54/133 (40%), Gaps = 25/133 (18%)

Query: 2   ASYPYRQGCPGAAGQ-----APGAPPGSYYPGPPNSGGQYGSGLPPG--------GGYGG 48
           A  P R G PG  G      +PG P     PGPP S G+ G   PPG        G  G 
Sbjct: 521 AGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGF 580

Query: 49  PAPGGPYGPPAGGGPYGHPNPGMFPSGTPG--------GPYGGAAPGGPYGQP-PPSSYG 99
           P P G  G P   G  G P  G  P G PG        GP G   PGG  G   PP   G
Sbjct: 581 PGPKGNDGAPGKNGERGGPG-GPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQG 639

Query: 100 AQQPGLYGQGGAP 112
            Q  GL G GG P
Sbjct: 640 LQ--GLPGTGGPP 650



 Score = 68.2 bits (165), Expect = 8e-12
 Identities = 53/123 (43%), Positives = 58/123 (47%), Gaps = 18/123 (14%)

Query: 5   PYRQGCPGAAGQ--APGAP--PG---SYYPGPPNSGGQYGS-----GLPPGGGYGGPAPG 52
           P R G PG  GQ  +PG+P  PG   S   GP N   QY S     G+  GG  G P P 
Sbjct: 117 PGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPA 176

Query: 53  GPYGPPAGGGPYGHPNPGMFP--SGTPGGPYGGAAPGGPYGQPPPSSYGAQQP-GLYGQG 109
           GP GPP   G  GHP     P   G PG P G A P GP G  PP + G   P G  G+ 
Sbjct: 177 GPPGPPGPPGTSGHPGSPGSPGYQGPPGEP-GQAGPSGPPG--PPGAIGPSGPAGKDGES 233

Query: 110 GAP 112
           G P
Sbjct: 234 GRP 236



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 49/127 (38%), Positives = 54/127 (42%), Gaps = 22/127 (17%)

Query: 2   ASYPYRQGCPGAAGQAPG-----APPG-------SYYPGPPNSGGQYGSGLPPG--GGYG 47
           A  P  +G PG AG APG      PPG       +  PGPP + G  G    PG  GG G
Sbjct: 677 AGAPGERGPPGLAG-APGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLG 735

Query: 48  GPAPGGPYGPPAGGGPYGHPNPGMFPSGTPGGPYGGAAPGGPYGQPPPSSYGAQQ--PGL 105
            P P G  G P G G  G P         P GP G   P GP GQP     G     PG+
Sbjct: 736 SPGPKGDKGEPGGPGADGVPG-----KDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGI 790

Query: 106 YGQGGAP 112
            G  G+P
Sbjct: 791 AGPRGSP 797



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 44/116 (37%), Positives = 51/116 (43%), Gaps = 11/116 (9%)

Query: 8   QGCPGAAGQAPGAPPGSYYPGPPNSGGQYGS----GLPPGGGYGGPAPGGPYGPPAGGGP 63
           +G PG  G+  G P  + +PG P   G+ G     G P   G GGP   G  GPP G GP
Sbjct: 794 RGSPGERGET-GPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPP--GVAGPPGGSGP 850

Query: 64  YGHPNPGMFPS--GTPGGPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGGAPPNVDP 117
            G P P       G+PGGP     PG      PP S G   PG  G  G+P    P
Sbjct: 851 AGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNG--NPGPPGPSGSPGKDGP 904



 Score = 58.5 bits (140), Expect = 6e-09
 Identities = 45/120 (37%), Positives = 49/120 (40%), Gaps = 22/120 (18%)

Query: 9   GCPGAAGQ--APGAPPGSYYPGPPNSGGQYGSGLPPG--------GGYGGPAPGGPYGPP 58
           G PG  G+   PG P      GPP   G+ G   PPG        G  G P P G  G P
Sbjct: 588 GAPGKNGERGGPGGPGPQ---GPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLP 644

Query: 59  AGGGP------YGHPNPGMFPSGTPGGPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGGAP 112
             GGP       G P P    +G PG P G    G P  + PP   GA  PGL G  G P
Sbjct: 645 GTGGPPGENGKPGEPGP-KGDAGAPGAPGGKGDAGAPGERGPPGLAGA--PGLRGGAGPP 701



 Score = 58.2 bits (139), Expect = 8e-09
 Identities = 43/118 (36%), Positives = 46/118 (38%), Gaps = 13/118 (11%)

Query: 5   PYRQGCPGAAGQAPGAPPGSYYPGPPNSGGQYGSGLPPG-----GGYGGPAPGGPYGPPA 59
           P   G PGA G  PG P  +  PGPP   G  G   PPG     G  G P   GP G   
Sbjct: 869 PGAAGFPGARG-LPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAG 927

Query: 60  GGGPYGHPNPGMFPSGTPG-----GPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGGAP 112
             G  G P     P G PG     G  G     GP G P P      Q G+ G+ G P
Sbjct: 928 QPGEKGSPG-AQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQ-GVKGESGKP 983



 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 49/139 (35%), Positives = 54/139 (38%), Gaps = 31/139 (22%)

Query: 5   PYRQGCPGAAGQ----------APGAPPGSYYP----GPPNSGGQYGSGLPPG--GGYGG 48
           P   G PGAAG+           P   PG   P    G P   G  G+   PG  G  GG
Sbjct: 473 PGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGG 532

Query: 49  PAPGGPYGPPAGGGPYGHPNP--GMFPSGTPGGPYGGAAPGGPYGQP-------PPSSYG 99
           P   G  G P G G  G P P      SG PG P     P GP GQP       P  + G
Sbjct: 533 PGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPP----GPSGPRGQPGVMGFPGPKGNDG 588

Query: 100 AQQPGLYGQGGAPPNVDPE 118
           A  PG  G+ G P    P+
Sbjct: 589 A--PGKNGERGGPGGPGPQ 605



 Score = 55.5 bits (132), Expect = 5e-08
 Identities = 48/132 (36%), Positives = 53/132 (40%), Gaps = 30/132 (22%)

Query: 5   PYRQGCPGAAGQA-PGAPPG----------SYYPGPPNSGGQYGSGLPPG--GGYGGPAP 51
           P  QG PG  G+  P  PPG          +  PGP    G  G+G PPG  G  G P P
Sbjct: 602 PGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGP 661

Query: 52  ---GGPYGPPAGGGPYGHPN----------PGMFPSGTPGGPYGGAAPGGPYGQPPPSSY 98
               G  G P G G  G P           PG+     P GP GG    GP G  PP + 
Sbjct: 662 KGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPG--PPGAA 719

Query: 99  GAQQPGLYGQGG 110
           G   PGL G  G
Sbjct: 720 GT--PGLQGMPG 729



 Score = 55.1 bits (131), Expect = 7e-08
 Identities = 49/147 (33%), Positives = 54/147 (36%), Gaps = 40/147 (27%)

Query: 5    PYRQGCPGAAGQ-----APGAPPGSYYPGPPNSGGQYG-------------SGLP-PGGG 45
            P R G PG  G      +PGAP    +PGPP   G  G             +G P P G 
Sbjct: 1022 PGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGS 1081

Query: 46   YGGPAPGGPYGPP------AGGGPYGH----PNPGMFPSGTPG-----GPYGGAAPGGPY 90
             G P P GP G           G  GH     NPG    G+PG     G  G   P GP 
Sbjct: 1082 RGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPG--APGSPGPAGQQGAIGSPGPAGPR 1139

Query: 91   GQPPPSSYGAQQPGLYGQGGAPPNVDP 117
            G   PS      PG  G  G P  + P
Sbjct: 1140 GPVGPSG----PPGKDGTSGHPGPIGP 1162



 Score = 54.7 bits (130), Expect = 9e-08
 Identities = 44/117 (37%), Positives = 46/117 (39%), Gaps = 13/117 (11%)

Query: 8   QGCPGAAGQA-----PGAPPGSYYPGPPNSGGQYGSGLPPG--GGYGGPAPGGPYGPPAG 60
           +G PG  G+       G P GS   GPP   G  G    PG  G  G P   G  GPP  
Sbjct: 827 RGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGS 886

Query: 61  GGPYGHPNPGMFP--SGTPGGPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGGA--PP 113
            G  G P P   P   G PG      APG P    P    G  QPG  G  GA  PP
Sbjct: 887 NGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAG--QPGEKGSPGAQGPP 941



 Score = 54.7 bits (130), Expect = 9e-08
 Identities = 41/114 (35%), Positives = 45/114 (39%), Gaps = 14/114 (12%)

Query: 8    QGCPGAAGQAPGAPPGSYYPGPPNSGGQYGSGLPPGGGYGGPAPGGPYGPPAGGGPYGHP 67
            +G  G  G   G P     PG P   GQ G+   PG   G   P GP GPP   G  GHP
Sbjct: 1100 RGAAGIKGHR-GFPGNPGAPGSPGPAGQQGAIGSPGPA-GPRGPVGPSGPPGKDGTSGHP 1157

Query: 68   NPGMFPS-----------GTPGGPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGG 110
             P   P            G+PG P G   P GP G P P   G     + G GG
Sbjct: 1158 GPIGPPGPRGNRGERGSEGSPGHP-GQPGPPGPPGAPGPCCGGVGAAAIAGIGG 1210



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 46/123 (37%), Positives = 50/123 (40%), Gaps = 20/123 (16%)

Query: 5   PYRQGCPGAAGQAPGAPPGSYYPGPPNSGGQYGSGLPPGGGYGGPAPGGPYGPPAGGGPY 64
           P   G PG  G  P  P G    GPP   GQ G     GG  G P   GP G P   G  
Sbjct: 749 PGADGVPGKDG--PRGPTGPI--GPPGPAGQPGDK-GEGGAPGLPGIAGPRGSPGERGET 803

Query: 65  GHPNPGMFP-----SGTPGGPYGGAAPG--GPYGQP----PPSSYGAQQP----GLYGQG 109
           G P P  FP     +G PGG     APG  G  G P    PP   G   P    G+ G+ 
Sbjct: 804 GPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGER 863

Query: 110 GAP 112
           G+P
Sbjct: 864 GSP 866



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 53/152 (34%), Positives = 57/152 (37%), Gaps = 44/152 (28%)

Query: 2   ASYPYRQGCPGAAGQAPGAPPGSYYPGPPNSGGQYGSGLPPGG----GYGGPA------- 50
           A  P   G PG +G  PG+P    Y GPP   GQ G   PPG     G  GPA       
Sbjct: 176 AGPPGPPGPPGTSGH-PGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESG 234

Query: 51  -PGGP-----YGPPAGGGPYGHPN-PGM-------------FPSGTPG--------GPYG 82
            PG P      GPP   GP G P  PGM               +G PG        G  G
Sbjct: 235 RPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENG 294

Query: 83  GAAPGGPYGQPPPSSYGAQQPGLYGQGGAPPN 114
              P GP G P        +PGL G  GA  N
Sbjct: 295 APGPMGPRGAPGERG----RPGLPGAAGARGN 322



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 47/134 (35%), Positives = 50/134 (37%), Gaps = 31/134 (23%)

Query: 7   RQGCPGAAGQA--PGAPPGSYYPGPPNSGGQYGSGLPPGGGYGGPAPGGPYGPPAGGGPY 64
           + G PG  G A  PGAP G    G P   G  G    PG   GG  P GP G     GP 
Sbjct: 655 KPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLR-GGAGPPGPEGGKGAAGPP 713

Query: 65  GHPNPGMFPS--GTPG--GPYGGAAPGGPYGQP----------------------PPSSY 98
           G P     P   G PG  G  G   P G  G+P                      PP   
Sbjct: 714 GPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPA 773

Query: 99  GAQQPGLYGQGGAP 112
           G  QPG  G+GGAP
Sbjct: 774 G--QPGDKGEGGAP 785



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 44/111 (39%), Positives = 45/111 (40%), Gaps = 18/111 (16%)

Query: 5    PYRQGCPGAAGQAPGAPPGSYYPGPPNSGGQYGSGLPPG--GGYGGPAPGGPYGPPAGGG 62
            P  QG PG AG A          G P   G  GS   PG  G  GG    G  G P   G
Sbjct: 995  PGPQGLPGLAGTA----------GEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPG 1044

Query: 63   PYGHPNPGMFPSGTPG--GPYGGAAPGGPYGQP-PPSSYGAQQPGLYGQGG 110
              GHP P   P G  G  G  G + P GP G P P  S GA  PG  G  G
Sbjct: 1045 APGHPGPPG-PVGPAGKSGDRGESGPAGPAGAPGPAGSRGA--PGPQGPRG 1092



 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 45/117 (38%), Positives = 49/117 (41%), Gaps = 23/117 (19%)

Query: 3   SYPYRQGCP--GAAGQ-APGAPPGSYYPGPPNSGGQYGSGLPPGGGYGGPAPG--GPYGP 57
           SY  + G    G AG   P  PPG   PGPP + G  GS  P   GY GP PG  G  GP
Sbjct: 157 SYDVKSGVAVGGLAGYPGPAGPPGP--PGPPGTSGHPGS--PGSPGYQGP-PGEPGQAGP 211

Query: 58  PAGGGPYGHPNPGMFPSGTPGGPYGGAAPG--GPYGQPPPSSYGAQQPGLYGQGGAP 112
               GP G     + PSG  G       PG  G  G P P       PG+ G  G P
Sbjct: 212 SGPPGPPG----AIGPSGPAGKDGESGRPGRPGERGLPGP-------PGIKGPAGIP 257



 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 46/124 (37%), Positives = 49/124 (39%), Gaps = 19/124 (15%)

Query: 8   QGCPGAAGQA--PGAPPGSYYPGPPNSGGQYGSGLPPG--GGYGGPAPGGPYGPPAGGGP 63
           +G PG  G+   PGA       G   S GQ G   PPG  G  G P   G  GP    G 
Sbjct: 302 RGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGS 361

Query: 64  YGHP----NPG-------MFPSGTPG--GPYGGAAPGGPYGQP-PPSSYGAQ-QPGLYGQ 108
            G P     PG         P G PG  G  GG    GP G P  P   GA+  PG  G 
Sbjct: 362 NGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGA 421

Query: 109 GGAP 112
            GAP
Sbjct: 422 NGAP 425



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 39/112 (34%), Positives = 47/112 (41%), Gaps = 13/112 (11%)

Query: 5   PYRQGCPGAAGQAPGAPPGSYYPGPPNSGGQYGSGLPPGGGYGGPAPGGPYGPPAGGGPY 64
           P   G PG  G   GAP     PG P + G  G+     G  G     GP GPP   G  
Sbjct: 290 PGENGAPGPMGPR-GAPGERGRPGLPGAAGARGND----GARGSDGQPGPPGPPGTAGFP 344

Query: 65  GHPNPG--MFPSGTPGGPYGGAAPGGPYGQPPPSSYGAQQ--PGLYGQGGAP 112
           G P     + P+G+PG      APG   G+P P  +   Q  PG  G  G+P
Sbjct: 345 GSPGAKGEVGPAGSPGS---NGAPG-QRGEPGPQGHAGAQGPPGPPGINGSP 392



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 42/113 (37%), Positives = 48/113 (42%), Gaps = 12/113 (10%)

Query: 8   QGCPGAAGQAPGAPPGSYYPGP---PNSGGQYGSGLPPG--GGYGGPAPGGPYGPPAGGG 62
           QG PG  G   G+P G    GP   P + G  G+  PPG  G  G P   G  G P   G
Sbjct: 380 QGPPGPPG-INGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNG 438

Query: 63  PYGHPNP--GMFPSGTPGGPYGGAAPGGPYGQP-PPSSYGAQQPGLYGQGGAP 112
             G P P      +G PG P G     G  G P  P + G   PG  G+ GAP
Sbjct: 439 AKGEPGPRGERGEAGIPGVP-GAKGEDGKDGSPGEPGANGL--PGAAGERGAP 488



 Score = 44.7 bits (104), Expect = 9e-05
 Identities = 41/116 (35%), Positives = 49/116 (42%), Gaps = 9/116 (7%)

Query: 2   ASYPYRQGCPGAAGQAPGAPPGSYYPGPPNSGGQYGSGLPPG--GGYGGPAPGGPYGPPA 59
           A  P + G  G  G   G    +  PG P + G+ G    PG  G  G P   G  G P 
Sbjct: 431 AGEPGKNGAKGEPGPR-GERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPG 489

Query: 60  GGGPYGHPN--PG-MFPSGTPGGPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGGAP 112
             GP G PN  PG   P+G  G P G A P G  G+P         PG+ G  G+P
Sbjct: 490 FRGPAG-PNGIPGEKGPAGERGAP-GPAGPRGAAGEPGRDGVPG-GPGMRGMPGSP 542



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 47/146 (32%), Positives = 54/146 (36%), Gaps = 45/146 (30%)

Query: 8   QGCPGAAGQAPGAP--------PG----------------SYYPGPPNSGGQYG------ 37
           +G PG AG A GAP        PG                +  PG P + G+ G      
Sbjct: 413 RGPPGPAG-ANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPG 471

Query: 38  ----SGLPPGGGYGGP----APGGPYGPPAGGGPYGH---PNPGMFPSGTPGGPYGGAAP 86
               +GLP   G  G      P GP G P   GP G    P P   P G  G P     P
Sbjct: 472 EPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPA-GPRGAAGEPGRDGVP 530

Query: 87  GGPYGQPPPSSYGAQQPGLYGQGGAP 112
           GGP  +  P S G   PG  G+ G P
Sbjct: 531 GGPGMRGMPGSPGG--PGSDGKPGPP 554



 Score = 37.4 bits (85), Expect = 0.015
 Identities = 45/132 (34%), Positives = 48/132 (36%), Gaps = 27/132 (20%)

Query: 9   GCPGAAGQAPGAPPGSYYPGPPNSGGQYG-SGLPPGGGYGG-----------PAPG---- 52
           G  G +G+ PG P     PGPP   G  G  G P   G+ G            APG    
Sbjct: 228 GKDGESGR-PGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGE 286

Query: 53  ----GPYGPPAGGGPYGHPNPGMFPSGTPG--GPYGGAAPGGPYGQP-PPSSYGAQQPGL 105
               G  G P   GP G P     P G PG  G  G     G  GQP PP   G    G 
Sbjct: 287 NGLPGENGAPGPMGPRGAPGERGRP-GLPGAAGARGNDGARGSDGQPGPPGPPGT--AGF 343

Query: 106 YGQGGAPPNVDP 117
            G  GA   V P
Sbjct: 344 PGSPGAKGEVGP 355



 Score = 35.8 bits (81), Expect = 0.044
 Identities = 36/123 (29%), Positives = 40/123 (32%), Gaps = 32/123 (26%)

Query: 27  PGPPNSGGQYGSGLPPGGGYGGPAP------GGPYGPPAGGGPYGHPNPGMFPSGTPGGP 80
           P PP +  +  +G  P G  G P P       G  G P   G  G P P       P GP
Sbjct: 89  PQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGP 148

Query: 81  -----------------YGGAA----PGGPYGQP-PPSSYG----AQQPGLYGQGGAPPN 114
                             GG A    P GP G P PP + G       PG  G  G P  
Sbjct: 149 QNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQ 208

Query: 115 VDP 117
             P
Sbjct: 209 AGP 211



 Score = 35.8 bits (81), Expect = 0.044
 Identities = 45/145 (31%), Positives = 51/145 (35%), Gaps = 38/145 (26%)

Query: 9   GCPGAAGQA--PGAPPGSYYPGPPNSGGQYGSGLPPG--------GGYGGPAPGGPYG-- 56
           G PG  G A  PG P    + G     G+ G    PG        G  G P P GP G  
Sbjct: 246 GPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAP 305

Query: 57  -----------PPAGG-----GPYGHPNPGMFPSGTPGGPYGGAAPG--GPYGQPPPSSY 98
                        A G     G  G P P   P GT G P    A G  GP G P  +  
Sbjct: 306 GERGRPGLPGAAGARGNDGARGSDGQPGP-PGPPGTAGFPGSPGAKGEVGPAGSPGSNGA 364

Query: 99  GAQ--QPGLYGQGGA-----PPNVD 116
             Q  +PG  G  GA     PP ++
Sbjct: 365 PGQRGEPGPQGHAGAQGPPGPPGIN 389



 Score = 31.6 bits (70), Expect = 0.83
 Identities = 26/78 (33%), Positives = 31/78 (39%), Gaps = 3/78 (3%)

Query: 2    ASYPYRQGCPGAAGQAP--GAPPGSYYPGPPNSGGQYGSGLPPGGGYGGPAPGGPYGPPA 59
            + +P   G PG  G     G+     +PG P   G  G+  P  GG G  A  G  G  A
Sbjct: 1154 SGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKA 1213

Query: 60   GG-GPYGHPNPGMFPSGT 76
            GG  PY    P  F   T
Sbjct: 1214 GGFAPYYGDEPMDFKINT 1231


>gi|221554549 calpain 8 [Homo sapiens]
          Length = 703

 Score = 65.1 bits (157), Expect = 7e-11
 Identities = 37/143 (25%), Positives = 68/143 (47%), Gaps = 2/143 (1%)

Query: 134 ISMKELKQALVNCNWSSFNDETCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQY 193
           I + E      +  +  FN  TC  MI++ D   +G +    F  LW  IQ++  ++ + 
Sbjct: 558 ILLNEAFSKRTDIKFDGFNINTCREMISLLDSNGTGTLGAVEFKTLWLKIQKYLEIYWET 617

Query: 194 DRDRSGSISYTELQQALSQMGYNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVL 253
           D + SG+I   E++ AL + G+ L+ Q  Q +  RY    +   +  D F+    +L+ L
Sbjct: 618 DYNHSGTIDAHEMRTALRKAGFTLNSQVQQTIALRYA--CSKLGINFDSFVACMIRLETL 675

Query: 254 TEAFREKDTAVQGNIRLSFEDFV 276
            + F   D    G ++LS  +++
Sbjct: 676 FKLFSLLDEDKDGMVQLSLAEWL 698


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 42/105 (40%), Positives = 46/105 (43%), Gaps = 11/105 (10%)

Query: 15  GQAPGAPPGSYYPGPPNSGGQYGSGLPPGGGYGGPAPGGPYGPPAGGGPYGHPNPGMFPS 74
           G  PGAPP    PG P   G     LPP     GP PG P GPP G      P PG+ P 
Sbjct: 433 GPPPGAPPFLRPPGMPGLRGPLPRLLPP-----GPPPGRPPGPPPG------PPPGLPPG 481

Query: 75  GTPGGPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGGAPPNVDPEA 119
             P GP     P  P G PPP     + P +   G APP + P A
Sbjct: 482 PPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPA 526



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 44/116 (37%), Positives = 47/116 (40%), Gaps = 30/116 (25%)

Query: 9   GCPGAAGQAP-----GAPPGSYYPGPPNSGGQYGSGLPPGGGYGGPAPGGP---YGPPAG 60
           G PG  G  P     G PPG   PGPP          PP G   GP P GP     PPA 
Sbjct: 446 GMPGLRGPLPRLLPPGPPPGRP-PGPPPG--------PPPGLPPGPPPRGPPPRLPPPAP 496

Query: 61  GGPYGHPNPGMF-PSGTPGGPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGGAPPNV 115
            G    P PGM  P   P  P G A PG     P P+      PG+     APPN+
Sbjct: 497 PG-IPPPRPGMMRPPLVP--PLGPAPPGLFPPAPLPN------PGVL---SAPPNL 540



 Score = 33.9 bits (76), Expect = 0.17
 Identities = 33/105 (31%), Positives = 37/105 (35%), Gaps = 23/105 (21%)

Query: 24  SYYPGPPNSGGQYGSGLPPGGGYGGPAPGGPYGPPAGGGPYGHPNPGMFPSGTPGGPYGG 83
           S    PP S       +PP      P PG P   P    P   P P   P+G P GP  G
Sbjct: 388 SQQQAPPQS-------VPPSQIQAPPMPGPPPLGPPPAPPLRPPGP---PTGLPPGPPPG 437

Query: 84  AAPG-GPYGQP----------PPSSYGAQQPGLYGQGGAPPNVDP 117
           A P   P G P          PP     + PG     G PP + P
Sbjct: 438 APPFLRPPGMPGLRGPLPRLLPPGPPPGRPPG--PPPGPPPGLPP 480


>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
          Length = 680

 Score = 62.8 bits (151), Expect = 3e-10
 Identities = 54/136 (39%), Positives = 59/136 (43%), Gaps = 24/136 (17%)

Query: 5   PYRQGCPGAAGQA-PGAPPGSYYPGPPNSGGQYG-SGLPPG-GGYGGPAPGGPYGPPAGG 61
           P  +G PGA G A P  PPG   PG P   G+ G +GLP G G  G   P G  G P   
Sbjct: 278 PGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLT 337

Query: 62  GPYGHPNPGMFPSGTPG-----GPYGGAAPGGPYGQP-------PPSSYGAQ----QPGL 105
           GP G+  P   P G PG     GP G   P GP G P        P S G      +PGL
Sbjct: 338 GPPGNMGP-QGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGL 396

Query: 106 YGQGGAP----PNVDP 117
            G  G P    P  DP
Sbjct: 397 DGPKGNPGLPGPKGDP 412



 Score = 58.5 bits (140), Expect = 6e-09
 Identities = 53/134 (39%), Positives = 58/134 (43%), Gaps = 24/134 (17%)

Query: 9   GCPGAAGQ--APGAPPGSYYPGPPNSGGQYGS-GLP-PGG--GYGGPAPG--GPYGPPAG 60
           G PGA G+  +PG+     YPG P   G  G+ GLP P G  G GGP PG  GP GP   
Sbjct: 371 GYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGP-PGLPGPVGPAGA 429

Query: 61  GGPYGHPNPGMFPSGTPGGPYGGAAPGGPYGQP-------------PPSSYGAQQPGLYG 107
            G  GH N    P G PG P G   P GP G P             PP   G    GL G
Sbjct: 430 KGMPGH-NGEAGPRGAPGIP-GTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNG 487

Query: 108 QGGAPPNVDPEAYS 121
             G P    P  +S
Sbjct: 488 PTGPPGPPGPRGHS 501



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 48/137 (35%), Positives = 55/137 (40%), Gaps = 30/137 (21%)

Query: 4   YPYRQGCPGAAGQ----------APGAP-----PGSYYP----GPPNSGGQYGSGLP--P 42
           +P  +G PG  G           APG P     PG   P    GPP  G +  +G+P  P
Sbjct: 172 FPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQP 231

Query: 43  G--------GGYGGPAPGGPYGPPAGGGPYGHPNPGMFPS-GTPGGPYGGAAPGGPYGQP 93
           G        G  G   P GP GPP   GP G   PG   + G PG P     PG P    
Sbjct: 232 GIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAG 291

Query: 94  PPSSYGAQQPGLYGQGG 110
           PP   G  +PGL G  G
Sbjct: 292 PPGPPGFGKPGLPGLKG 308



 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 44/105 (41%), Positives = 47/105 (44%), Gaps = 15/105 (14%)

Query: 8   QGCPGAAG-QAPGAPPGSYYPGPPNSGGQYGSGLPPG-GGYGGPAPGGPYGPPAGGGPYG 65
           +G PG  G + P  PPG   PG P S G  GS  PPG  G       GP GPP   GP G
Sbjct: 442 RGAPGIPGTRGPIGPPG--IPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRG 499

Query: 66  HPNPGMFPSGTPGGPYGGAAPGGPYGQ---PPPSSYGAQQPGLYG 107
           H       SG PG P G   P GP GQ   P       Q+P L G
Sbjct: 500 H-------SGEPGLP-GPPGPPGPPGQAVMPEGFIKAGQRPSLSG 536



 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 48/123 (39%), Positives = 50/123 (40%), Gaps = 20/123 (16%)

Query: 5   PYRQGCPGAAG----QAPGAPPGSYYPGPPNSGGQYGSGLPPG--GGYGGPAPGGPYGPP 58
           P  QG PG  G     A G P     PG P   G YG   P G  G  G P P GP GPP
Sbjct: 88  PGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYG---PKGDVGPAGLPGPRGPPGPP 144

Query: 59  AGGGPYGHPNPG----MFPSGTPG-----GPYGGAAPGGPYGQPPPSSYGAQQPGLYGQG 109
              GP G   PG      P+G PG     G  G     G  GQ     YGA  PG  G+ 
Sbjct: 145 GIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGA--PGRPGER 202

Query: 110 GAP 112
           G P
Sbjct: 203 GLP 205



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 47/120 (39%), Positives = 53/120 (44%), Gaps = 26/120 (21%)

Query: 8   QGCPGAAGQAPGAPPGSYYPGPPNSGGQYGSGLPPGGGYGGPAPGGPYGPPAGG------ 61
           QG PG  G  P  P G  +PGP    G+ G G P  G  G P   GP GP A G      
Sbjct: 59  QGTPGPPG--PAGPRG--HPGPSGPPGKPGYGSP--GLQGEPGLPGPPGPSAVGKPGVPG 112

Query: 62  --------GPYGHPNPGMFPSGTPGGPYGGAAPGGPYGQPPPSSYGAQ-QPGLYGQGGAP 112
                   GPYG P   + P+G P GP G   P GP G P P+      +PG  G  GAP
Sbjct: 113 LPGKPGERGPYG-PKGDVGPAGLP-GPRG---PPGPPGIPGPAGISVPGKPGQQGPTGAP 167



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 46/127 (36%), Positives = 50/127 (39%), Gaps = 27/127 (21%)

Query: 8   QGCPGAAGQAPGAPPGSYYPGPPNSGGQYGSGLPPGGGYGG-PAPGGPYGPPAGGGPYGH 66
           +G PG  G  P  PPG    GPP   G  G G P   G  G P   G  G P   G  G 
Sbjct: 237 RGFPGEMG--PIGPPGPQ--GPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGP 292

Query: 67  PNPGMF-------------PSGTPGGPYGGAAPGGPYGQP-------PPSSYGAQQP-GL 105
           P P  F             P+G PGGP G     GP G P       PP + G Q P G+
Sbjct: 293 PGPPGFGKPGLPGLKGERGPAGLPGGP-GAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGI 351

Query: 106 YGQGGAP 112
            G  G P
Sbjct: 352 PGSHGLP 358



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 46/118 (38%), Positives = 47/118 (39%), Gaps = 20/118 (16%)

Query: 9   GCPGAAG-QAPGAPPGSY-YPGPP-NSGGQYGSGLPPGGGYGGP----APGGPYGPPAGG 61
           G PGA G Q P   PG     GPP N G Q   G+P   G  GP     P GP G P   
Sbjct: 317 GGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAK 376

Query: 62  GPYGHPNPGMFPS--GTPG--GPYGGAAPGGPYGQP----PPSSYGAQQPGLYGQGGA 111
           G  G P     P   G PG  GP G     GP G P    PP       PG  G  GA
Sbjct: 377 GERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPG-----LPGPVGPAGA 429



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 48/119 (40%), Positives = 51/119 (42%), Gaps = 15/119 (12%)

Query: 5   PYRQGCPGAAGQAPGAPPGSYYPGPPNSGGQYGS------GLPPGGGYGGP-APGGPYGP 57
           P +QG  GA G   G P     PG P   GQ G       G P   G  GP  P GP GP
Sbjct: 158 PGQQGPTGAPGPR-GFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGP 216

Query: 58  PAGG--GPYGHPN-PGMFPSGTPGGPYGGAAPGGPYG-QPPPSSYGAQQPGLYGQGGAP 112
           P  G  G  G P  PG+   G  G P G   P GP G Q PP   G +  G  G  GAP
Sbjct: 217 PGVGKRGENGVPGQPGI--KGDRGFP-GEMGPIGPPGPQGPPGERGPEGIGKPGAAGAP 272



 Score = 45.1 bits (105), Expect = 7e-05
 Identities = 39/99 (39%), Positives = 41/99 (41%), Gaps = 13/99 (13%)

Query: 34  GQYGSGLPPG--GGYGGPAPGGPYGPPAGGGP--YGHPN----PGMFPSGTPGGPYGGAA 85
           G+ G+  PPG  G  G P P GP G P  G P   G P     PG    G PG P     
Sbjct: 57  GEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGK 116

Query: 86  PG--GPYGQPPPSSYG-AQQPGLYGQGGAPPNVDPEAYS 121
           PG  GPYG  P    G A  PG  G  G P    P   S
Sbjct: 117 PGERGPYG--PKGDVGPAGLPGPRGPPGPPGIPGPAGIS 153



 Score = 36.6 bits (83), Expect = 0.026
 Identities = 23/61 (37%), Positives = 26/61 (42%), Gaps = 5/61 (8%)

Query: 63  PYGHPNPGMFPSGTPGGPYGGAAPGGPYGQP----PPSSYGAQQPGLYGQGGAPPNVDPE 118
           PY   + G+   G  G P G   P GP G P    PP   G   PGL G+ G P    P 
Sbjct: 45  PYTIKSKGIAVRGEQGTP-GPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPS 103

Query: 119 A 119
           A
Sbjct: 104 A 104


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 47/114 (41%), Positives = 51/114 (44%), Gaps = 12/114 (10%)

Query: 5   PYRQGCPGAAG-QAPGAPPGSYYPGPPNSGGQYG-SGLPPGGGYGGPAPGGPYGPPAGGG 62
           P  QG PG  G Q    P G   PGPP   G  G +G+   G  G P  GG  GPP   G
Sbjct: 175 PGAQGVPGPPGFQGEPGPQGE--PGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPG 232

Query: 63  PYGHPNPGMFPSGTPGGPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGGAPPNVD 116
           P G   PG+   G PG P G     GP G P P      +PG  G  G PP VD
Sbjct: 233 PAGLGKPGL--DGLPGAP-GDKGESGPPGVPGPRG----EPGAVGPKG-PPGVD 278



 Score = 55.1 bits (131), Expect = 7e-08
 Identities = 47/123 (38%), Positives = 50/123 (40%), Gaps = 19/123 (15%)

Query: 9   GCPGAAGQ-APGAPPGSYY---PGPPNSGGQYGSGLPPG-----GGYGGPAPGGPYGPPA 59
           G PG  GQ  P  PPG       GPP   G+ G    PG     G  G     GP GPP 
Sbjct: 103 GKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPG 162

Query: 60  GGGPYGHPNPGMFPSGTPGGPYGGAAPGGPYGQPPP-------SSYGAQQPGL---YGQG 109
             GP G   PG   +    GP G     GP G+P P          G  QPGL    GQG
Sbjct: 163 LPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQG 222

Query: 110 GAP 112
           GAP
Sbjct: 223 GAP 225



 Score = 55.1 bits (131), Expect = 7e-08
 Identities = 48/139 (34%), Positives = 53/139 (38%), Gaps = 29/139 (20%)

Query: 5   PYRQGCPGAAG-QAPGAPPGSYYPGPPNSGGQYGSGLPPG-------GGYGGPAPGGPYG 56
           P   G PGA G +    PPG   PGP    G  G   PPG       G  G P P GP G
Sbjct: 239 PGLDGLPGAPGDKGESGPPG--VPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSG 296

Query: 57  ---------PPAGGGPYGHPNPGM-------FPSGTPG--GPYGGAAPGGPYGQPPPSSY 98
                    PP   GP G+  PG+        P+G PG  G  G     G  G+  P   
Sbjct: 297 AKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGL 356

Query: 99  GAQQPGLYGQGGAPPNVDP 117
           G   PGL G  G P    P
Sbjct: 357 GG-PPGLPGSAGLPGRRGP 374



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 48/125 (38%), Positives = 50/125 (40%), Gaps = 16/125 (12%)

Query: 2   ASYPYRQGCPGAAGQA-----PG--APPGSYYPGPPNSGGQYGSGLPPG-----GGYGGP 49
           A  P  QG  GA G+      PG   P G   PG P   G  G    PG     G  G  
Sbjct: 286 AGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGED 345

Query: 50  APGGPYGPPAGGGPYGHPNPGMFPSGT-PGGPYGGAAPGGPYGQPPPSSYGAQQP-GLYG 107
              G  GP   GGP G P     P    P GP G A PGGP G   P   G Q P GL G
Sbjct: 346 GEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPG--VPGIRGDQGPSGLAG 403

Query: 108 QGGAP 112
           + G P
Sbjct: 404 KPGVP 408



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 45/116 (38%), Positives = 48/116 (41%), Gaps = 21/116 (18%)

Query: 2   ASYPYRQGCPGAAGQA-PGAPPGSYYPGPPNSGGQYGSGLPPGGGYGGPAPGGPYGPPAG 60
           A  P R+G PG  G+A PG PPG      P   G  G    P G  G P   G  G P  
Sbjct: 366 AGLPGRRGPPGPKGEAGPGGPPGV-----PGIRGDQG----PSGLAGKPGVPGERGLPGA 416

Query: 61  GGPYGHPNPGMFP--SGTPGGPYGGAAPG--GPYGQPPPSSYGAQQPGLYGQGGAP 112
            GP G   P   P  +G PGGP    A G  G  G P        QPGL G  G P
Sbjct: 417 HGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLP-------GQPGLRGPSGIP 465



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 48/131 (36%), Positives = 52/131 (39%), Gaps = 20/131 (15%)

Query: 5   PYRQGCPGAAGQ----APGAPPG-SYYPGPPNSGGQYGS----GLPPGGGYGGPA----- 50
           P  +G PGA G      P   PG +  PG P   G  G     GLP   G  GP+     
Sbjct: 408 PGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGL 467

Query: 51  --PGGPYGPPAGGGPYGHPN-PGMFPSGTPGGPYGGAAPGGPYGQP--PPSSYGAQQPGL 105
             P GP GP    G  G P  PG    G  G P G A P GP G P  P  +     PG 
Sbjct: 468 QGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEP-GTAGPTGPPGVPGSPGITGPPGPPGP 526

Query: 106 YGQGGAPPNVD 116
            G  GAP   D
Sbjct: 527 PGPPGAPGAFD 537



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 47/138 (34%), Positives = 52/138 (37%), Gaps = 35/138 (25%)

Query: 7   RQGCPGAAGQAPGAPPGSYYP-------GPP--NSGGQY-------------GSGLPPGG 44
           R    G AG A G  P  Y         GPP     GQY             G   PPG 
Sbjct: 25  RASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGK 84

Query: 45  GYGGPAPGGPYGPPAGGGPYGHPNPGMFPSGTPGGPYGGAAPG--GPYGQP----PPSSY 98
               P P GP GPP   G  G   PG+     P GP G +  G  GP G P    PP   
Sbjct: 85  ----PGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQP 140

Query: 99  GAQ-QPGLYGQGG--APP 113
           G + +PG+ G  G   PP
Sbjct: 141 GLRGEPGIRGDQGLRGPP 158



 Score = 44.7 bits (104), Expect = 9e-05
 Identities = 43/139 (30%), Positives = 50/139 (35%), Gaps = 23/139 (16%)

Query: 8   QGCPGAAGQAPG--APPGSYYPGPPNSGGQYGSGLPPG--GGYGGPAPGGPYGPPAGGGP 63
           QG PG  G+ PG   PPG    G P + G  G    PG  G  G P P GP GPP  G P
Sbjct: 477 QGLPGLKGE-PGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPP--GAP 533

Query: 64  YGHPNPGMFPSGTPGGPYGGAAPG---------GPYGQPPPSSYGAQQPGLYGQGGAPPN 114
                 G+     P G   GA  G         G        ++ A     +   G P  
Sbjct: 534 GAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVK 593

Query: 115 VDPEAYSWFQSVDSDHSGY 133
            D   Y       + HSGY
Sbjct: 594 FDRTLY-------NGHSGY 605



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 34/95 (35%), Positives = 38/95 (40%), Gaps = 19/95 (20%)

Query: 43  GGGYGG-----------PAPGGPYGPP--AGGGPYGHPNPGMFPSGTPG--GPYGGAAPG 87
           GGG GG           P   GP GPP   G G Y      + P    G  GP G   P 
Sbjct: 29  GGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPR 88

Query: 88  GPYGQPP-PSSYGAQQPGLYGQGGAPPNVDPEAYS 121
           GP G P  P   G  +PGL+GQ   P    P  +S
Sbjct: 89  GPPGPPGFPGKPGMGKPGLHGQ---PGPAGPPGFS 120


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 62.0 bits (149), Expect = 6e-10
 Identities = 46/111 (41%), Positives = 51/111 (45%), Gaps = 12/111 (10%)

Query: 8    QGCPGAAGQAPGAPPGSYYPGPPNSGGQYGSGLPPGGGYGGPAPGGPYGPPAGGGPYGHP 67
            +G PG AG+ PG P     PGP    G+ G   P G       P GP GPP   GP G P
Sbjct: 1284 KGEPGEAGE-PGLPGEGGPPGPKGERGEKGESGPSGAA----GPPGPKGPPGDDGPKGSP 1338

Query: 68   NPGMFPSGTPGGPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGGAP-PNVDP 117
             P  FP G PG P G   P G  G  PP   G    G  GQ G+P P  +P
Sbjct: 1339 GPVGFP-GDPGPP-GEPGPAGQDG--PPGDKG--DDGEPGQTGSPGPTGEP 1383



 Score = 61.6 bits (148), Expect = 7e-10
 Identities = 50/128 (39%), Positives = 53/128 (41%), Gaps = 19/128 (14%)

Query: 2    ASYPYRQGCPGAAGQA--PGAPPGSYYPGPPNSGGQYGSGLPPG--------GGYGGPAP 51
            A  P  +G  GAAG    PG P     PGP    G  G   P G        G  G P P
Sbjct: 1086 AGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGP 1145

Query: 52   GGPYGPPAGGGPYGH-PNPGMFPS-GTPG--GPYGGAAPGGPYGQPPPSSYGAQ-----Q 102
             GP GPP   G  G    PG   S G  G  GP G   P GP GQP PS    +     Q
Sbjct: 1146 AGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQ 1205

Query: 103  PGLYGQGG 110
             GL+GQ G
Sbjct: 1206 QGLFGQKG 1213



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 45/112 (40%), Positives = 47/112 (41%), Gaps = 9/112 (8%)

Query: 8   QGCPGAAGQAPGAPPGSYYPGPPNSGGQYGSGLPPG-----GGYGGPAPGGPYGPPAGGG 62
           +G PG  G  PG       PGP  + G  G   PPG     G  G P P G  GPP   G
Sbjct: 687 KGPPGPPGP-PGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKG 745

Query: 63  PYGHPN-PGM-FPSGTPGGPYGGAAPGGPYGQPPPSSYG-AQQPGLYGQGGA 111
           P G P  PGM    G PG P     PG   GQ PP   G    PG  G  GA
Sbjct: 746 PLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGA 797



 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 49/127 (38%), Positives = 52/127 (40%), Gaps = 23/127 (18%)

Query: 9   GCPGAAGQAPGAPPGSYYPGPPNSGGQYGS-------GLP----PGGGYGGPAPGGPYGP 57
           G PG  G   G P  S  PGPP   G+ G        GLP    P G  G   P GP GP
Sbjct: 637 GLPGEKGHR-GDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGP 695

Query: 58  PAGGGPYGHPNP--GMFPSGTPGGPYGGAAPG-----GPYGQ--PPPSSYGAQQPGLYGQ 108
           P   G  G P P   + P G PG P     PG     GP G   PP       +PGL G 
Sbjct: 696 PGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGM 755

Query: 109 GGA--PP 113
            GA  PP
Sbjct: 756 PGADGPP 762



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 48/133 (36%), Positives = 50/133 (37%), Gaps = 27/133 (20%)

Query: 5    PYRQGCPGAAGQ-------APGAPPGSYYPGPPNSGGQYGSGLPPG--------GGYGGP 49
            P  QG PG AG+        P   PG    GPP   G  G    PG        G  G P
Sbjct: 1023 PGEQGLPGLAGKEGTKGDPGPAGLPGK--DGPPGLRGFPGDRGLPGPVGALGLKGNEGPP 1080

Query: 50   APGGPYGPPAGGGPYGHPNPGMFPSGTPGGPYGGAAPGGPYGQP-PPSSYGAQQP----G 104
             P GP G P   GP G       P G PG P G   P GP G+   P   G Q P    G
Sbjct: 1081 GPPGPAGSPGERGPAGAAG----PIGIPGRP-GPQGPPGPAGEKGAPGEKGPQGPAGRDG 1135

Query: 105  LYGQGGAPPNVDP 117
            L G  G P    P
Sbjct: 1136 LQGPVGLPGPAGP 1148



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 43/122 (35%), Positives = 45/122 (36%), Gaps = 36/122 (29%)

Query: 8    QGCPGAAGQAPGAPPGSYYP-------------------------GPPNSGGQYGS-GLP 41
            QG PG+ G  P  PPG   P                         GPP   G+ G  GLP
Sbjct: 1449 QGLPGSPG--PDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1506

Query: 42   PGGGYGGP-------APGGPYGPPAGGGPYGHPNP-GMFPSGTPGGPYGGAAPGGPYGQP 93
               G  GP        P GP GPP   G  G P P G   S  P GP G A   GP G P
Sbjct: 1507 GPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPP 1566

Query: 94   PP 95
             P
Sbjct: 1567 GP 1568



 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 51/146 (34%), Positives = 54/146 (36%), Gaps = 34/146 (23%)

Query: 1    MASYPYRQGCPGAAG-----QAPGAPPGSYYPGPPNSGGQYGSGLP-----PGGGYGGPA 50
            +  YP RQG  G+ G      A G   G   PG P   GQ G   P     P G  G P 
Sbjct: 872  LPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPG 931

Query: 51   P------GGPYGPPAGGGPYGHPNPGMF--PSGTPGGPYGGAAPG-----------GPYG 91
            P       GP GPP   GP G   P  F  P G PG P     PG           G  G
Sbjct: 932  PKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 991

Query: 92   QP-PPSSYGAQQP----GLYGQGGAP 112
             P PP   G Q P    G  G+ G P
Sbjct: 992  PPGPPGVVGPQGPTGETGPMGERGHP 1017



 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 41/111 (36%), Positives = 46/111 (41%), Gaps = 16/111 (14%)

Query: 9    GCPGAAGQAPGAPPGSYYPGPPNSGGQYGSGLPPG--GGYGGPAPGGPYGPPAGGGPYGH 66
            G PGA G  P  PPG    G P + G+ G    PG  G  G P  GGP GP    G  G 
Sbjct: 1261 GAPGADG--PQGPPGGI--GNPGAVGEKGE---PGEAGEPGLPGEGGPPGPKGERGEKGE 1313

Query: 67   PNPGMFPSGTPGGPYGGAAPGGPYGQPPPSSYGAQ-----QPGLYGQGGAP 112
              P    +  P GP G     GP G P P  +        +PG  GQ G P
Sbjct: 1314 SGPS--GAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPP 1362



 Score = 52.0 bits (123), Expect = 6e-07
 Identities = 50/147 (34%), Positives = 53/147 (36%), Gaps = 26/147 (17%)

Query: 5    PYRQGCPGAAG----QAPGAPPGSYYP-GPPNSGGQYGSGLPPG--------GGYGGPAP 51
            P  +G  G AG    Q P   PG   P GPP   G  G    PG        G  G P P
Sbjct: 1122 PGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGP 1181

Query: 52   GGPYGP---PAGGGPYGHPNP----GMFPSGTPGGPYGGAAPGGPYG----QPPPSSYGA 100
             GP GP   P   G  G P P    G+F      GP G   P GP G      PP   G 
Sbjct: 1182 TGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKG- 1240

Query: 101  QQPGLYGQGGAPPNVDPEAYSWFQSVD 127
             + G  GQ G P    P   S     D
Sbjct: 1241 -ETGDVGQMGPPGPPGPRGPSGAPGAD 1266



 Score = 52.0 bits (123), Expect = 6e-07
 Identities = 44/118 (37%), Positives = 46/118 (38%), Gaps = 16/118 (13%)

Query: 5    PYRQGCPGAAGQ-APGAPPGSYYP-GPPNSGGQYGSGLPPGGGYGGPAPGGPYGPPAGGG 62
            P  +G  G  GQ  P  PPG   P G P + G  G    P GG G P   G  G P   G
Sbjct: 1236 PGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQG----PPGGIGNPGAVGEKGEPGEAG 1291

Query: 63   PYGHPNPGMFPSGTPG--------GPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGGAP 112
              G P  G  P G  G        GP G A P GP G PP        PG  G  G P
Sbjct: 1292 EPGLPGEG-GPPGPKGERGEKGESGPSGAAGPPGPKG-PPGDDGPKGSPGPVGFPGDP 1347



 Score = 52.0 bits (123), Expect = 6e-07
 Identities = 47/140 (33%), Positives = 53/140 (37%), Gaps = 24/140 (17%)

Query: 2    ASYPYRQGCPGAAGQ--APGAPPGSYYPGPPNSGGQYGSGLPPG--------GGYGGPAP 51
            A  P  +G PG  G   +PG       PGPP   G  G   PPG        G  G P P
Sbjct: 1320 AGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGP 1379

Query: 52   GGPYGPPAGGGPYGHPNPGMFPSGTPG-----------GPYGGAAPGGPYGQP-PPSSYG 99
             G  GP    G  G P P   P G  G           GP G   P GP G P  P   G
Sbjct: 1380 TGEPGPSGPPGKRGPPGPA-GPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDG 1438

Query: 100  AQQ-PGLYGQGGAPPNVDPE 118
             +  PG  G+ G P +  P+
Sbjct: 1439 LRGIPGPVGEQGLPGSPGPD 1458



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 45/117 (38%), Positives = 50/117 (42%), Gaps = 19/117 (16%)

Query: 7    RQGCPGAAGQAP-GAPPGSYYP-GPPNSGGQYGSGLPPGGGYGGPAPGGPYGPPAGGGPY 64
            RQG  GA G+A    PPG   P GP  + G+ G    P G  G P P G  G P   GP 
Sbjct: 1403 RQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPG----PDGLRGIPGPVGEQGLPGSPGPD 1458

Query: 65   GHPNPGMFPSGTPGGPYGGAAPGGPYGQP-------PPSSYGAQ----QPGLYGQGG 110
            G P P M P G P G  G + P G  G P       PP   G +     PG  G  G
Sbjct: 1459 GPPGP-MGPPGLP-GLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSG 1513



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 45/135 (33%), Positives = 51/135 (37%), Gaps = 31/135 (22%)

Query: 4   YPYRQGCPGA-AGQAPGAPPGSY-YPGP------------PNSGGQYGSGLPPG------ 43
           +P ++G PG   GQ P  P G   YPGP              + G+ G    PG      
Sbjct: 764 HPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMG 823

Query: 44  -----GGYGGPAP---GGPYGPPAGGGPYGHPNPGMFPSGTPGGPYGGAAPGGPYGQPPP 95
                G  G P P    GP GP   GGP G P P + P G  G       PG P  Q P 
Sbjct: 824 IKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGP-LGPPGEKGKLGVPGLPGYPGRQGPK 882

Query: 96  SSYGAQQPGLYGQGG 110
            S G   PG  G  G
Sbjct: 883 GSIGF--PGFPGANG 895



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 44/127 (34%), Positives = 48/127 (37%), Gaps = 21/127 (16%)

Query: 5    PYRQGCPGAAGQAPGAPPGSYYPGPPNSGGQYGSGLPPG-----------GGYGGPAPGG 53
            P  +G  G  GQ     P  + PGPP   G  G   PPG           G  G P P G
Sbjct: 1200 PGPRGQQGLFGQKGDEGPRGF-PGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRG 1258

Query: 54   PYGPPAGGGPYGH----PNPGMFPSGTPGGPYGGAAPGGPYGQPPPSSYGAQ-QPGLYGQ 108
            P G P   GP G      NPG    G  G P     PG P    PP   G + + G  G 
Sbjct: 1259 PSGAPGADGPQGPPGGIGNPGAV--GEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGP 1316

Query: 109  GGA--PP 113
             GA  PP
Sbjct: 1317 SGAAGPP 1323



 Score = 44.7 bits (104), Expect = 9e-05
 Identities = 39/106 (36%), Positives = 42/106 (39%), Gaps = 7/106 (6%)

Query: 9    GCPGAAGQAPGAPPGSYYPGPPNSGGQYG--SGLPPGGGYGGPAPGGPYGPPAGGGPYGH 66
            G PG  G  PG P     PG P   G+ G      P G  G   P GP G     G  GH
Sbjct: 958  GFPGPKGP-PGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGH 1016

Query: 67   PNPGMFPSGTPGGPYGGAAPGGPYGQPPPSSYGAQQ--PGLYGQGG 110
            P P   P G  G P G A   G  G P P+    +   PGL G  G
Sbjct: 1017 PGP-PGPPGEQGLP-GLAGKEGTKGDPGPAGLPGKDGPPGLRGFPG 1060



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 45/146 (30%), Positives = 50/146 (34%), Gaps = 35/146 (23%)

Query: 5   PYRQGCPGAAGQAPGAPPGSYY--PGPPNSGGQYGSGLP--------------------- 41
           P R G PGA G  PG PPG+    P     GG  GS  P                     
Sbjct: 501 PGRPGLPGADG-LPG-PPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALR 558

Query: 42  -PGGGYGGPAPGGPYGPPAGGGPYGHPNPGMFPSGTPGGPYGGAAPGGPYGQPPPSSYGA 100
            P G  G     GP GPP  GG  G P         P GP G   P GP G+P       
Sbjct: 559 GPAGPMGLTGRPGPVGPPGSGGLKGEPG-----DVGPQGPRGVQGPPGPAGKPGRRG--- 610

Query: 101 QQPGLYGQGGAPPNVDPEAYSWFQSV 126
            + G  G  G P    P+    F  +
Sbjct: 611 -RAGSDGARGMPGQTGPKGDRGFDGL 635



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 26/54 (48%), Positives = 27/54 (50%), Gaps = 5/54 (9%)

Query: 8    QGCPGAAGQ-APGAPPGSYYPGPPNSGGQYGSGLPPG--GGYGGPAPGGPYGPP 58
            QG  G +G   P  PPG   PGPP   G  GS  P G  G  G P P GP GPP
Sbjct: 1518 QGITGPSGPIGPPGPPG--LPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPP 1569



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 42/122 (34%), Positives = 47/122 (38%), Gaps = 22/122 (18%)

Query: 9   GCPGAAGQ-APGAPPGSYYP-------GPPNSGGQYG-SGLPPGGGYGGP--APGGPYGP 57
           G PG  G+  P  P G   P       GPP   G+ G  GLP   G  GP  + G P  P
Sbjct: 832 GPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFP 891

Query: 58  PAGGGPYGHPNPGMFPSGTPG--GPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGGAPPNV 115
            A G   G         GTPG  GP G   P GP G+  P      +PG  G  G     
Sbjct: 892 GANGEKGGR--------GTPGKPGPRGQRGPTGPRGERGPRGI-TGKPGPKGNSGGDGPA 942

Query: 116 DP 117
            P
Sbjct: 943 GP 944



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 32/99 (32%), Positives = 36/99 (36%), Gaps = 17/99 (17%)

Query: 26  YPGPPNSGGQYGSGLPPGGGYGGPAPGGPYGPPAGGGPYGHPNPGMFPSGTPG------- 78
           Y  P +S  + G G+P          GGP G     G      PGM   G PG       
Sbjct: 420 YYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGL 479

Query: 79  -GPYGGAAPGGPYGQP----PPSSYGAQQPGLYGQGGAP 112
            GP G   P G  G P    PP      +PGL G  G P
Sbjct: 480 PGPPGTMGPTGQVGDPGERGPPG-----RPGLPGADGLP 513



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 40/117 (34%), Positives = 43/117 (36%), Gaps = 13/117 (11%)

Query: 8   QGCPGAAGQAPGAPPGSYYPGPPNSGGQYGSGLPPG-----GGYGGPAPGGPYGPPAGGG 62
           +G  G  G+     PG    GPP   G  G   PPG     G  G P   GP G P   G
Sbjct: 449 RGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPG 508

Query: 63  PYGHPNPG----MFPSGTPGGPYGGAAPGGPYGQPPPSSYGA--QQPGLYGQGGAPP 113
             G P P     M P    GG  G A   GP      S   A  QQ  L  +G A P
Sbjct: 509 ADGLPGPPGTMLMLPFRFGGG--GDAGSKGPMVSAQESQAQAILQQARLALRGPAGP 563


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.137    0.442 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,940,688
Number of Sequences: 37866
Number of extensions: 1438209
Number of successful extensions: 22758
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 568
Number of HSP's successfully gapped in prelim test: 1025
Number of HSP's that attempted gapping in prelim test: 6084
Number of HSP's gapped (non-prelim): 6972
length of query: 284
length of database: 18,247,518
effective HSP length: 101
effective length of query: 183
effective length of database: 14,423,052
effective search space: 2639418516
effective search space used: 2639418516
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.