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Search of human proteins with 58533161
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens]
(214 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens] 437 e-123
gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens] 403 e-113
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens] 327 6e-90
gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens] 210 6e-55
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens] 197 7e-51
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens] 176 1e-44
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens] 170 7e-43
gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens] 119 1e-27
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 119 1e-27
gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens] 117 7e-27
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 117 7e-27
gi|13994151 PDZ and LIM domain 1 [Homo sapiens] 105 2e-23
gi|196162711 PDZ and LIM domain 4 isoform 2 [Homo sapiens] 92 4e-19
gi|19923181 PDZ and LIM domain 4 isoform 1 [Homo sapiens] 92 4e-19
gi|166235178 PDZ and LIM domain protein 3 isoform b [Homo sapiens] 87 8e-18
gi|166235176 PDZ and LIM domain protein 3 isoform a [Homo sapiens] 87 8e-18
gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens] 86 2e-17
gi|28866957 PDZ and LIM domain 2 isoform 1 [Homo sapiens] 86 2e-17
gi|21361888 PDZ and LIM domain 2 isoform 2 [Homo sapiens] 86 2e-17
gi|166706868 synaptopodin 2-like isoform a [Homo sapiens] 67 1e-11
gi|193083191 synaptopodin 2 isoform c [Homo sapiens] 65 6e-11
gi|193083185 synaptopodin 2 isoform b [Homo sapiens] 65 6e-11
gi|193083183 synaptopodin 2 isoform a [Homo sapiens] 65 6e-11
gi|118600967 shroom family member 4 [Homo sapiens] 59 3e-09
gi|218505835 membrane-associated guanylate kinase-related 3 iso... 56 3e-08
gi|4502175 apical protein of Xenopus-like [Homo sapiens] 54 1e-07
gi|153070254 MAGI family member, X-linked isoform b [Homo sapiens] 54 1e-07
gi|153070258 MAGI family member, X-linked isoform a [Homo sapiens] 52 3e-07
gi|203098098 shroom family member 3 protein [Homo sapiens] 50 1e-06
gi|13376349 PDZ domain containing 7 [Homo sapiens] 50 1e-06
>gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens]
Length = 214
Score = 437 bits (1125), Expect = e-123
Identities = 214/214 (100%), Positives = 214/214 (100%)
Query: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG
Sbjct: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
Query: 61 MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKKTQVTNNPGTVKIPPKRPPRKHI 120
MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKKTQVTNNPGTVKIPPKRPPRKHI
Sbjct: 61 MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKKTQVTNNPGTVKIPPKRPPRKHI 120
Query: 121 VERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNT 180
VERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNT
Sbjct: 121 VERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNT 180
Query: 181 KKAKEKIPLHVFSPKYTKLRDWHHEVSARALNVQ 214
KKAKEKIPLHVFSPKYTKLRDWHHEVSARALNVQ
Sbjct: 181 KKAKEKIPLHVFSPKYTKLRDWHHEVSARALNVQ 214
>gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens]
Length = 234
Score = 403 bits (1036), Expect = e-113
Identities = 205/234 (87%), Positives = 206/234 (88%), Gaps = 20/234 (8%)
Query: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG
Sbjct: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
Query: 61 MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKKT--------------------Q 100
MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQK T Q
Sbjct: 61 MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTVTSVCSETSQELAEGQRRGSQ 120
Query: 101 VTNNPGTVKIPPKRPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSF 160
+ KIPPKRPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSF
Sbjct: 121 GDSKQQNGKIPPKRPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSF 180
Query: 161 RILAQITGTEHLKESEADNTKKAKEKIPLHVFSPKYTKLRDWHHEVSARALNVQ 214
RILAQITGTEHLKESEADNTKKAKEKIPLHVFSPKYTKLRDWHHEVSARALNVQ
Sbjct: 181 RILAQITGTEHLKESEADNTKKAKEKIPLHVFSPKYTKLRDWHHEVSARALNVQ 234
>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
Length = 487
Score = 327 bits (837), Expect = 6e-90
Identities = 170/198 (85%), Positives = 171/198 (86%), Gaps = 16/198 (8%)
Query: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG
Sbjct: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
Query: 61 MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKKT---------------QVTNNP 105
MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQK T Q +
Sbjct: 61 MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTVTSVCSETSQELAEGQRRGSQ 120
Query: 106 GTVKIPPKRPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQ 165
G K PPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQ
Sbjct: 121 GDSK-QQNGPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQ 179
Query: 166 ITGTEHLKESEADNTKKA 183
ITGTEHLKESEADNTKKA
Sbjct: 180 ITGTEHLKESEADNTKKA 197
>gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens]
Length = 222
Score = 210 bits (535), Expect = 6e-55
Identities = 113/221 (51%), Positives = 143/221 (64%), Gaps = 7/221 (3%)
Query: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
M ++ V L GPAPWGFRLQGGKDFN+PL+IS L GGKAAQA V +GD VLSIDG NA
Sbjct: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
Query: 61 MTHLEAQNKIKGCTGSLNMTLQRA---SAAPKPEPVPVQKKTQVTNNPGT----VKIPPK 113
+TH+EAQNKI+ C L++ L RA + P+ P + T P P
Sbjct: 61 LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120
Query: 114 RPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLK 173
PP + P DASK+RL+E+TEDWRPR GT QSRSFRILA +TGTE ++
Sbjct: 121 APPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ 180
Query: 174 ESEADNTKKAKEKIPLHVFSPKYTKLRDWHHEVSARALNVQ 214
+ + ++ KK++EK L + SP+YT+LRDWHH+ SA LNVQ
Sbjct: 181 DPDEEHLKKSREKYVLELQSPRYTRLRDWHHQRSAHVLNVQ 221
>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
Length = 596
Score = 197 bits (500), Expect = 7e-51
Identities = 97/97 (100%), Positives = 97/97 (100%)
Query: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG
Sbjct: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
Query: 61 MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQK 97
MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQK
Sbjct: 61 MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQK 97
Score = 145 bits (366), Expect = 3e-35
Identities = 69/69 (100%), Positives = 69/69 (100%)
Query: 115 PPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKE 174
PPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKE
Sbjct: 238 PPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKE 297
Query: 175 SEADNTKKA 183
SEADNTKKA
Sbjct: 298 SEADNTKKA 306
>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
Length = 423
Score = 176 bits (446), Expect = 1e-44
Identities = 97/185 (52%), Positives = 121/185 (65%), Gaps = 27/185 (14%)
Query: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
M ++ V L GPAPWGFRLQGGKDFN+PL+IS L GGKAAQA V +GD VLSIDG NA
Sbjct: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
Query: 61 MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKKTQVTNNPGTVKIPPKRPPRKHI 120
+TH+EAQNKI+ C L++ L RA PVQ K P V+ P K+P R
Sbjct: 61 LTHIEAQNKIRACGERLSLGLSRAQ--------PVQSK------PQKVQTPDKQPLR--- 103
Query: 121 VERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNT 180
P DASK+RL+E+TEDWRPR GT QSRSFRILA +TGTE +++ + ++
Sbjct: 104 ----------PLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQDPDEEHL 153
Query: 181 KKAKE 185
KK+ +
Sbjct: 154 KKSSQ 158
>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
Length = 457
Score = 170 bits (431), Expect = 7e-43
Identities = 94/192 (48%), Positives = 120/192 (62%), Gaps = 7/192 (3%)
Query: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
M ++ V L GPAPWGFRLQGGKDFN+PL+IS L GGKAAQA V +GD VLSIDG NA
Sbjct: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
Query: 61 MTHLEAQNKIKGCTGSLNMTLQRA---SAAPKPEPVPVQKKTQVTNNPGT----VKIPPK 113
+TH+EAQNKI+ C L++ L RA + P+ P + T P P
Sbjct: 61 LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120
Query: 114 RPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLK 173
PP + P DASK+RL+E+TEDWRPR GT QSRSFRILA +TGTE ++
Sbjct: 121 APPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ 180
Query: 174 ESEADNTKKAKE 185
+ + ++ KK+ +
Sbjct: 181 DPDEEHLKKSSQ 192
>gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens]
Length = 330
Score = 119 bits (299), Expect = 1e-27
Identities = 71/164 (43%), Positives = 91/164 (55%), Gaps = 26/164 (15%)
Query: 3 NYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMT 62
+YSV+L GP PWGFRLQGGKDFNMPLTIS + G KAAQ+ + GD+V++IDG+N MT
Sbjct: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
Query: 63 HLEAQNKIKGCTGSLNMTLQRA--------SAAPKPEPVPV---QKKTQVTNN------- 104
HLEAQNKIK + +L++TLQ++ +A P P+PV QK + N
Sbjct: 62 HLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAPS 121
Query: 105 --------PGTVKIPPKRPPRKHIVERYTEFYHVPTHSDASKKR 140
PGT P RP R + F + SD R
Sbjct: 122 PSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPR 165
Score = 73.6 bits (179), Expect = 1e-13
Identities = 31/78 (39%), Positives = 55/78 (70%)
Query: 137 SKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNTKKAKEKIPLHVFSPKY 196
S+ + ++ ++W R+ QSRSFRILAQ+TGTE +++ + + ++++E+ SP++
Sbjct: 252 SQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSRERFETERNSPRF 311
Query: 197 TKLRDWHHEVSARALNVQ 214
KLR+WHH +SA+ LNV+
Sbjct: 312 AKLRNWHHGLSAQILNVK 329
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 119 bits (299), Expect = 1e-27
Identities = 71/164 (43%), Positives = 91/164 (55%), Gaps = 26/164 (15%)
Query: 3 NYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMT 62
+YSV+L GP PWGFRLQGGKDFNMPLTIS + G KAAQ+ + GD+V++IDG+N MT
Sbjct: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
Query: 63 HLEAQNKIKGCTGSLNMTLQRA--------SAAPKPEPVPV---QKKTQVTNN------- 104
HLEAQNKIK + +L++TLQ++ +A P P+PV QK + N
Sbjct: 62 HLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAPS 121
Query: 105 --------PGTVKIPPKRPPRKHIVERYTEFYHVPTHSDASKKR 140
PGT P RP R + F + SD R
Sbjct: 122 PSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPR 165
Score = 43.1 bits (100), Expect = 2e-04
Identities = 18/51 (35%), Positives = 34/51 (66%)
Query: 137 SKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNTKKAKEKI 187
S+ + ++ ++W R+ QSRSFRILAQ+TGTE +++ + + +++ I
Sbjct: 252 SQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSSTPI 302
>gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens]
Length = 283
Score = 117 bits (293), Expect = 7e-27
Identities = 59/110 (53%), Positives = 77/110 (70%), Gaps = 8/110 (7%)
Query: 3 NYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMT 62
+YSV+L GP PWGFRLQGGKDFNMPLTIS + G KAAQ+ + GD+V++IDG+N MT
Sbjct: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
Query: 63 HLEAQNKIKGCTGSLNMTLQRA--------SAAPKPEPVPVQKKTQVTNN 104
HLEAQNKIK + +L++TLQ++ +A P P+PV +V N
Sbjct: 62 HLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVN 111
Score = 73.6 bits (179), Expect = 1e-13
Identities = 31/78 (39%), Positives = 55/78 (70%)
Query: 137 SKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNTKKAKEKIPLHVFSPKY 196
S+ + ++ ++W R+ QSRSFRILAQ+TGTE +++ + + ++++E+ SP++
Sbjct: 205 SQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSRERFETERNSPRF 264
Query: 197 TKLRDWHHEVSARALNVQ 214
KLR+WHH +SA+ LNV+
Sbjct: 265 AKLRNWHHGLSAQILNVK 282
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 117 bits (293), Expect = 7e-27
Identities = 59/110 (53%), Positives = 77/110 (70%), Gaps = 8/110 (7%)
Query: 3 NYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMT 62
+YSV+L GP PWGFRLQGGKDFNMPLTIS + G KAAQ+ + GD+V++IDG+N MT
Sbjct: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
Query: 63 HLEAQNKIKGCTGSLNMTLQRA--------SAAPKPEPVPVQKKTQVTNN 104
HLEAQNKIK + +L++TLQ++ +A P P+PV +V N
Sbjct: 62 HLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVN 111
Score = 43.1 bits (100), Expect = 2e-04
Identities = 17/48 (35%), Positives = 34/48 (70%)
Query: 137 SKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNTKKAK 184
S+ + ++ ++W R+ QSRSFRILAQ+TGTE +++ + + ++++
Sbjct: 205 SQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSR 252
>gi|13994151 PDZ and LIM domain 1 [Homo sapiens]
Length = 329
Score = 105 bits (263), Expect = 2e-23
Identities = 49/84 (58%), Positives = 60/84 (71%)
Query: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
M+ + L GP PWGFRL GGKDF PL IS + G KAA AN+ IGDV+ +IDG N
Sbjct: 1 MTTQQIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSN 60
Query: 61 MTHLEAQNKIKGCTGSLNMTLQRA 84
MTHLEAQN+IKGCT +L +T+ R+
Sbjct: 61 MTHLEAQNRIKGCTDNLTLTVARS 84
>gi|196162711 PDZ and LIM domain 4 isoform 2 [Homo sapiens]
Length = 246
Score = 91.7 bits (226), Expect = 4e-19
Identities = 47/97 (48%), Positives = 64/97 (65%), Gaps = 1/97 (1%)
Query: 4 YSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTH 63
+SV+L GP+PWGFRL GG+DF+ PLTIS + G KAA A + GD++ +I+G + + MTH
Sbjct: 3 HSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTH 62
Query: 64 LEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKKTQ 100
LEAQN+IKGC L +++ R P P K Q
Sbjct: 63 LEAQNRIKGCHDHLTLSVSRPEGRSWPS-APDDSKAQ 98
>gi|19923181 PDZ and LIM domain 4 isoform 1 [Homo sapiens]
Length = 330
Score = 91.7 bits (226), Expect = 4e-19
Identities = 47/97 (48%), Positives = 64/97 (65%), Gaps = 1/97 (1%)
Query: 4 YSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTH 63
+SV+L GP+PWGFRL GG+DF+ PLTIS + G KAA A + GD++ +I+G + + MTH
Sbjct: 3 HSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTH 62
Query: 64 LEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKKTQ 100
LEAQN+IKGC L +++ R P P K Q
Sbjct: 63 LEAQNRIKGCHDHLTLSVSRPEGRSWPS-APDDSKAQ 98
>gi|166235178 PDZ and LIM domain protein 3 isoform b [Homo
sapiens]
Length = 316
Score = 87.4 bits (215), Expect = 8e-18
Identities = 41/79 (51%), Positives = 53/79 (67%)
Query: 5 SVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHL 64
+V L GPAPWGFRL GG DFN PL I+ + G KAA AN+ GDV+L+IDG + MTH
Sbjct: 4 TVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHA 63
Query: 65 EAQNKIKGCTGSLNMTLQR 83
+AQ++IK L + + R
Sbjct: 64 DAQDRIKAAAHQLCLKIDR 82
>gi|166235176 PDZ and LIM domain protein 3 isoform a [Homo
sapiens]
Length = 364
Score = 87.4 bits (215), Expect = 8e-18
Identities = 41/79 (51%), Positives = 53/79 (67%)
Query: 5 SVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHL 64
+V L GPAPWGFRL GG DFN PL I+ + G KAA AN+ GDV+L+IDG + MTH
Sbjct: 4 TVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHA 63
Query: 65 EAQNKIKGCTGSLNMTLQR 83
+AQ++IK L + + R
Sbjct: 64 DAQDRIKAAAHQLCLKIDR 82
>gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens]
Length = 278
Score = 85.9 bits (211), Expect = 2e-17
Identities = 36/82 (43%), Positives = 59/82 (71%)
Query: 5 SVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHL 64
+V + GPAPWGFR+ GG+DF+ P+ ++ + + GKA A++R GD++++I+G +A+GM H
Sbjct: 4 TVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGMLHA 63
Query: 65 EAQNKIKGCTGSLNMTLQRASA 86
EAQ+KI+ L + L R+ A
Sbjct: 64 EAQSKIRQSPSPLRLQLDRSQA 85
>gi|28866957 PDZ and LIM domain 2 isoform 1 [Homo sapiens]
Length = 366
Score = 85.9 bits (211), Expect = 2e-17
Identities = 36/82 (43%), Positives = 59/82 (71%)
Query: 5 SVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHL 64
+V + GPAPWGFR+ GG+DF+ P+ ++ + + GKA A++R GD++++I+G +A+GM H
Sbjct: 4 TVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGMLHA 63
Query: 65 EAQNKIKGCTGSLNMTLQRASA 86
EAQ+KI+ L + L R+ A
Sbjct: 64 EAQSKIRQSPSPLRLQLDRSQA 85
>gi|21361888 PDZ and LIM domain 2 isoform 2 [Homo sapiens]
Length = 352
Score = 85.9 bits (211), Expect = 2e-17
Identities = 36/82 (43%), Positives = 59/82 (71%)
Query: 5 SVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHL 64
+V + GPAPWGFR+ GG+DF+ P+ ++ + + GKA A++R GD++++I+G +A+GM H
Sbjct: 4 TVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGMLHA 63
Query: 65 EAQNKIKGCTGSLNMTLQRASA 86
EAQ+KI+ L + L R+ A
Sbjct: 64 EAQSKIRQSPSPLRLQLDRSQA 85
>gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]
Length = 977
Score = 66.6 bits (161), Expect = 1e-11
Identities = 42/137 (30%), Positives = 67/137 (48%), Gaps = 6/137 (4%)
Query: 6 VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLE 65
V+L G APWGFRL GG + PL +S ++ +A +A +R D +L+I+G++ ++H
Sbjct: 9 VTLSGGAPWGFRLHGGAEQRKPLQVSKIRRRSQAGRAGLRERDQLLAINGVSCTNLSHAS 68
Query: 66 AQNKIKGCTGSLNMTLQR-ASAAPKPEPVP-----VQKKTQVTNNPGTVKIPPKRPPRKH 119
A + I L +T+QR A P P P + + ++ P +P P
Sbjct: 69 AMSLIDASGNQLVLTVQRLADEGPVQSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSL 128
Query: 120 IVERYTEFYHVPTHSDA 136
+E Y+ T SDA
Sbjct: 129 RSPPDSEAYYGETDSDA 145
>gi|193083191 synaptopodin 2 isoform c [Homo sapiens]
Length = 1109
Score = 64.7 bits (156), Expect = 6e-11
Identities = 31/81 (38%), Positives = 51/81 (62%)
Query: 6 VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLE 65
+S+ G APWGFRLQGGK+ PL ++ +++ KA+ + + GD V+SI+G +T+ E
Sbjct: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
Query: 66 AQNKIKGCTGSLNMTLQRASA 86
++ T SL M ++R S+
Sbjct: 69 VIKLMESITDSLQMLIKRPSS 89
>gi|193083185 synaptopodin 2 isoform b [Homo sapiens]
Length = 1093
Score = 64.7 bits (156), Expect = 6e-11
Identities = 31/81 (38%), Positives = 51/81 (62%)
Query: 6 VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLE 65
+S+ G APWGFRLQGGK+ PL ++ +++ KA+ + + GD V+SI+G +T+ E
Sbjct: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
Query: 66 AQNKIKGCTGSLNMTLQRASA 86
++ T SL M ++R S+
Sbjct: 69 VIKLMESITDSLQMLIKRPSS 89
>gi|193083183 synaptopodin 2 isoform a [Homo sapiens]
Length = 1261
Score = 64.7 bits (156), Expect = 6e-11
Identities = 31/81 (38%), Positives = 51/81 (62%)
Query: 6 VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLE 65
+S+ G APWGFRLQGGK+ PL ++ +++ KA+ + + GD V+SI+G +T+ E
Sbjct: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
Query: 66 AQNKIKGCTGSLNMTLQRASA 86
++ T SL M ++R S+
Sbjct: 69 VIKLMESITDSLQMLIKRPSS 89
>gi|118600967 shroom family member 4 [Homo sapiens]
Length = 1493
Score = 58.9 bits (141), Expect = 3e-09
Identities = 35/82 (42%), Positives = 50/82 (60%), Gaps = 2/82 (2%)
Query: 6 VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAA-QANVRIGDVVLSIDGINAQGMTHL 64
V L G APWGF L+GG + PLT+S ++DGGKAA +R GD +++I+G G +
Sbjct: 13 VQLQGGAPWGFTLKGGLEHCEPLTVSKIEDGGKAALSQKMRTGDELVNINGTPLYG-SRQ 71
Query: 65 EAQNKIKGCTGSLNMTLQRASA 86
EA IKG L + ++R +A
Sbjct: 72 EALILIKGSFRILKLIVRRRNA 93
>gi|218505835 membrane-associated guanylate kinase-related 3 isoform
1 [Homo sapiens]
Length = 1481
Score = 55.8 bits (133), Expect = 3e-08
Identities = 40/143 (27%), Positives = 67/143 (46%), Gaps = 12/143 (8%)
Query: 10 GPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQ-ANVRIGDVVLSIDGINAQGMTHLEAQN 68
GP +GF L+GGK++NM L I L + G A + + +GD ++ I+G QG+TH A
Sbjct: 1027 GPRGFGFSLRGGKEYNMGLFILRLAEDGPAIKDGRIHVGDQIVEINGEPTQGITHTRAIE 1086
Query: 69 KIKGCTGSLNMTLQRASAAPKPEPVPVQKKTQVTNNPGTVKI----PPKRPPRKHIVERY 124
I+ + + L+ P +P + NNP + + PP H +
Sbjct: 1087 LIQAGGNKVLLLLR-----PGTGLIPDHGDWDI-NNPSSSNVIYDEQSPLPPSSHFASIF 1140
Query: 125 TEFYHVPTHSDASKKRLIEDTED 147
E HVP ++ + ++ E E+
Sbjct: 1141 EE-SHVPVIEESLRVQICEKAEE 1162
Score = 33.5 bits (75), Expect = 0.14
Identities = 39/145 (26%), Positives = 60/145 (41%), Gaps = 17/145 (11%)
Query: 14 WGFRLQGGKDFNMPLTISS-LKDGGKAAQANVRIGDVVLSIDGINAQGMTHLEAQN--KI 70
+GF + GG + L + + LKDG A + GDV++ I+G G TH + ++
Sbjct: 420 FGFTIIGGDRPDEFLQVKNVLKDGPAAQDGKIAPGDVIVDINGNCVLGHTHADVVQMFQL 479
Query: 71 KGCTGSLNMTLQRASAAPKPEPVPV---QKKTQVTNNPGTVK-----IPPKRPPRKHIVE 122
+N+TL R P PV T V N K P P ++E
Sbjct: 480 VPVNQYVNLTLCRGYPLPDDSEDPVVDIVAATPVINGQSLTKGETCMNPQDFKPGAMVLE 539
Query: 123 RYTEFYHVPT------HSDASKKRL 141
+ + H T SDAS++R+
Sbjct: 540 QNGKSGHTLTGDGLNGPSDASEQRV 564
>gi|4502175 apical protein of Xenopus-like [Homo sapiens]
Length = 1616
Score = 53.9 bits (128), Expect = 1e-07
Identities = 30/81 (37%), Positives = 47/81 (58%), Gaps = 2/81 (2%)
Query: 6 VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQAN-VRIGDVVLSIDGINAQGMTHL 64
V L G APWGF L+GG++ PL I+ +++G KAA + + GD ++ I+ I G
Sbjct: 29 VQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQ- 87
Query: 65 EAQNKIKGCTGSLNMTLQRAS 85
EA +KG +L + ++R S
Sbjct: 88 EAICLVKGSHKTLKLVVKRRS 108
>gi|153070254 MAGI family member, X-linked isoform b [Homo sapiens]
Length = 262
Score = 53.5 bits (127), Expect = 1e-07
Identities = 42/145 (28%), Positives = 71/145 (48%), Gaps = 13/145 (8%)
Query: 3 NYSVSLV-GPAPWGFRLQGGKDF--NMPLTISSL-KDGGKAAQANVRIGDVVLSIDGINA 58
++SV LV G A +G L GG+D + PL + L KDG + +GD+VL I+G +
Sbjct: 56 HFSVELVRGYAGFGLTLGGGRDVAGDTPLAVRGLLKDGPAQRCGRLEVGDLVLHINGEST 115
Query: 59 QGMTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPV---QKKTQVTNNPGTVKIPPKRP 115
QG+TH +A +I+ L++ ++R +P V +K + +PG ++ R
Sbjct: 116 QGLTHAQAVERIRAGGPQLHLVIRRPLETHPGKPRGVGEPRKGVDRSPDPGGPEVTGSRS 175
Query: 116 PRKHIVERYTEFYHVPTHSDASKKR 140
+V+ H P+ + K R
Sbjct: 176 SSTSLVQ------HPPSRTTLKKTR 194
>gi|153070258 MAGI family member, X-linked isoform a [Homo sapiens]
Length = 334
Score = 52.4 bits (124), Expect = 3e-07
Identities = 44/150 (29%), Positives = 73/150 (48%), Gaps = 18/150 (12%)
Query: 3 NYSVSLV-GPAPWGFRLQGGKDF--NMPLTISSL-KDGGKAAQANVRIGDVVLSIDGINA 58
++SV LV G A +G L GG+D + PL + L KDG + +GD+VL I+G +
Sbjct: 123 HFSVELVRGYAGFGLTLGGGRDVAGDTPLAVRGLLKDGPAQRCGRLEVGDLVLHINGEST 182
Query: 59 QGMTHLEAQNKIKGCTGSLNMTLQR--ASAAPKPEPVPVQKKTQVTN------NPGTVKI 110
QG+TH +A +I+ L++ ++R + KP V +K V + +PG ++
Sbjct: 183 QGLTHAQAVERIRAGGPQLHLVIRRPLETHPGKPRGVGEPRKGVVPSWPDRSPDPGGPEV 242
Query: 111 PPKRPPRKHIVERYTEFYHVPTHSDASKKR 140
R +V+ H P+ + K R
Sbjct: 243 TGSRSSSTSLVQ------HPPSRTTLKKTR 266
>gi|203098098 shroom family member 3 protein [Homo sapiens]
Length = 1996
Score = 50.4 bits (119), Expect = 1e-06
Identities = 28/78 (35%), Positives = 46/78 (58%), Gaps = 3/78 (3%)
Query: 8 LVGPAPWGFRLQGGKDFNMPLTISSLKDGGKA--AQANVRIGDVVLSIDGINAQGMTHLE 65
L G APWGF L+GG + PL IS +++GGKA + ++ GD V+ I+ + + E
Sbjct: 32 LEGGAPWGFTLKGGLEHGEPLIISKVEEGGKADTLSSKLQAGDEVVHINEVTLSS-SRKE 90
Query: 66 AQNKIKGCTGSLNMTLQR 83
A + +KG +L + ++R
Sbjct: 91 AVSLVKGSYKTLRLVVRR 108
>gi|13376349 PDZ domain containing 7 [Homo sapiens]
Length = 517
Score = 50.1 bits (118), Expect = 1e-06
Identities = 22/74 (29%), Positives = 44/74 (59%), Gaps = 1/74 (1%)
Query: 15 GFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLEAQNKIKGCT 74
GF ++GGK+F + + +S + GG A + +++GD VL+ +G+ ++H +A +KG T
Sbjct: 223 GFNIRGGKEFGLGIYVSKVDHGGLAEENGIKVGDQVLAANGVRFDDISHSQAVEVLKGQT 282
Query: 75 GSLNMTLQRASAAP 88
+ +T++ P
Sbjct: 283 -HIMLTIKETGRYP 295
Score = 39.7 bits (91), Expect = 0.002
Identities = 17/74 (22%), Positives = 42/74 (56%), Gaps = 1/74 (1%)
Query: 15 GFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLEAQNKIKGCT 74
GF ++GG + + + +S +++G A +A + +GD + ++G++ + T + + K+ +
Sbjct: 98 GFSVRGGSEHGLGIFVSKVEEGSSAERAGLCVGDKITEVNGLSLESTT-MGSAVKVLTSS 156
Query: 75 GSLNMTLQRASAAP 88
L+M ++R P
Sbjct: 157 SRLHMMVRRMGRVP 170
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,701,993
Number of Sequences: 37866
Number of extensions: 407385
Number of successful extensions: 1508
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 123
Number of HSP's successfully gapped in prelim test: 50
Number of HSP's that attempted gapping in prelim test: 1251
Number of HSP's gapped (non-prelim): 287
length of query: 214
length of database: 18,247,518
effective HSP length: 98
effective length of query: 116
effective length of database: 14,536,650
effective search space: 1686251400
effective search space used: 1686251400
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.