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Search of human proteins with 54607031
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54607031 immunoglobulin superfamily, member 4D [Homo
sapiens]
(437 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens] 871 0.0
gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens] 387 e-107
gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens] 385 e-107
gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Ho... 342 4e-94
gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Ho... 312 4e-85
gi|21686977 cell adhesion molecule 4 [Homo sapiens] 236 3e-62
gi|166295173 kin of IRRE like [Homo sapiens] 96 5e-20
gi|221316762 neurotrimin isoform 4 [Homo sapiens] 89 6e-18
gi|221316757 neurotrimin isoform 3 [Homo sapiens] 89 6e-18
gi|112789532 poliovirus receptor related 2 isoform delta precurs... 89 6e-18
gi|7705413 neurotrimin isoform 1 [Homo sapiens] 89 6e-18
gi|51593098 class-I MHC-restricted T cell associated molecule [H... 88 2e-17
gi|115298665 neurotrimin isoform 2 [Homo sapiens] 88 2e-17
gi|11386199 poliovirus receptor-related 3 [Homo sapiens] 88 2e-17
gi|109150416 peroxidasin [Homo sapiens] 87 2e-17
gi|4505505 opioid binding protein/cell adhesion molecule-like is... 87 3e-17
gi|45594240 limbic system-associated membrane protein [Homo sapi... 87 3e-17
gi|59939900 opioid binding protein/cell adhesion molecule-like i... 86 9e-17
gi|4507875 vascular cell adhesion molecule 1 isoform a precursor... 85 1e-16
gi|18201909 vascular cell adhesion molecule 1 isoform b precurso... 83 6e-16
gi|157819143 IgLON family member 5 [Homo sapiens] 83 6e-16
gi|110349719 titin isoform N2-A [Homo sapiens] 82 7e-16
gi|157311649 neogenin homolog 1 [Homo sapiens] 82 1e-15
gi|5360210 poliovirus receptor related 2 isoform alpha precursor... 82 1e-15
gi|33519481 neural cell adhesion molecule 2 precursor [Homo sapi... 80 3e-15
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 80 4e-15
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 80 4e-15
gi|118572606 hemicentin 1 [Homo sapiens] 80 5e-15
gi|126517478 peroxidasin homolog-like [Homo sapiens] 78 2e-14
gi|145275174 kin of IRRE-like 2 isoform c [Homo sapiens] 78 2e-14
>gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]
Length = 437
Score = 871 bits (2250), Expect = 0.0
Identities = 437/437 (100%), Positives = 437/437 (100%)
Query: 1 MFVLFLCNLSLVPAAASKNKVKGSQGQFPLTQNVTVVEGGTAILTCRVDQNDNTSLQWSN 60
MFVLFLCNLSLVPAAASKNKVKGSQGQFPLTQNVTVVEGGTAILTCRVDQNDNTSLQWSN
Sbjct: 1 MFVLFLCNLSLVPAAASKNKVKGSQGQFPLTQNVTVVEGGTAILTCRVDQNDNTSLQWSN 60
Query: 61 PAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYL 120
PAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYL
Sbjct: 61 PAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYL 120
Query: 121 TVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDAN 180
TVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDAN
Sbjct: 121 TVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDAN 180
Query: 181 RKTFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFP 240
RKTFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFP
Sbjct: 181 RKTFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFP 240
Query: 241 QEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEA 300
QEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEA
Sbjct: 241 QEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEA 300
Query: 301 TNTIGQSSAEYVLIVHDVPNTLLPTTIIPSLTTATVTTTVAITTSPTTSATTSSIRDPNA 360
TNTIGQSSAEYVLIVHDVPNTLLPTTIIPSLTTATVTTTVAITTSPTTSATTSSIRDPNA
Sbjct: 301 TNTIGQSSAEYVLIVHDVPNTLLPTTIIPSLTTATVTTTVAITTSPTTSATTSSIRDPNA 360
Query: 361 LAGQNGPDHALIGGIVAVVVFVTLCSIFLLGRYLARHKGTYLTNEAKGAEDAPDADTAII 420
LAGQNGPDHALIGGIVAVVVFVTLCSIFLLGRYLARHKGTYLTNEAKGAEDAPDADTAII
Sbjct: 361 LAGQNGPDHALIGGIVAVVVFVTLCSIFLLGRYLARHKGTYLTNEAKGAEDAPDADTAII 420
Query: 421 NAEGSQVNAEEKKEYFI 437
NAEGSQVNAEEKKEYFI
Sbjct: 421 NAEGSQVNAEEKKEYFI 437
>gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]
Length = 432
Score = 387 bits (993), Expect = e-107
Identities = 197/414 (47%), Positives = 266/414 (64%), Gaps = 43/414 (10%)
Query: 24 SQGQFPLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVR 83
SQ P T + TVV GGT +L C+V ++++SLQWSNPAQQTLYF +K+ALRDNRI+LV
Sbjct: 62 SQDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVT 121
Query: 84 ASWHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDL 143
++ HELSIS+S+V+L+DEG+YTCS+FTMPV+T+K+ +TVLG+P+KP I+G+ S + E D
Sbjct: 122 STPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDT 181
Query: 144 MQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAV 203
L C++SGSKPAA + W K D+E+ +ED N KTFTVSS++ F+V R DDG ++
Sbjct: 182 ATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASI 241
Query: 204 ICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLW 263
+C V+HESL + Q +E+ YTP+ I P P P+EGQ L+L CE +G P+P+ LW
Sbjct: 242 VCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLW 301
Query: 264 TKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLL 323
K+G P + L FLNK+D+GTY C AT+ +G A Y L
Sbjct: 302 EKEGSV---PPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTL---------- 348
Query: 324 PTTIIPSLTTATVTTTVAITTSPTTSATTSSIRDPNALAGQNGPDHALIGGIVAVVVFVT 383
++ DP+ + + HA+IGGIVA +VF+
Sbjct: 349 ------------------------------NVNDPSPVPSSSSTYHAIIGGIVAFIVFLL 378
Query: 384 LCSIFLLGRYLARHKGTYLTNEAKGAEDAPDADTAIINAEGSQVNAEEKKEYFI 437
L + LG YL RHKGTYLT+EAKG++DAPDADTAIINAEG Q ++KKEYFI
Sbjct: 379 LIMLIFLGHYLIRHKGTYLTHEAKGSDDAPDADTAIINAEGGQSGGDDKKEYFI 432
>gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]
Length = 398
Score = 385 bits (988), Expect = e-107
Identities = 195/409 (47%), Positives = 264/409 (64%), Gaps = 43/409 (10%)
Query: 29 PLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHE 88
P T + TVV GGT +L C+V ++++SLQWSNPAQQTLYF +K+ALRDNRI+LV ++ HE
Sbjct: 33 PWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHE 92
Query: 89 LSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTC 148
LSIS+S+V+L+DEG+YTCS+FTMPV+T+K+ +TVLG+P+KP I+G+ S + E D L C
Sbjct: 93 LSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNC 152
Query: 149 KTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVD 208
++SGSKPAA + W K D+E+ +ED N KTFTVSS++ F+V R DDG +++C V+
Sbjct: 153 QSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVN 212
Query: 209 HESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGG 268
HESL + Q +E+ YTP+ I P P P+EGQ L+L CE +G P+P+ LW K+G
Sbjct: 213 HESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGS 272
Query: 269 ELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLLPTTII 328
P + L FLNK+D+GTY C AT+ +G A Y L
Sbjct: 273 V---PPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTL--------------- 314
Query: 329 PSLTTATVTTTVAITTSPTTSATTSSIRDPNALAGQNGPDHALIGGIVAVVVFVTLCSIF 388
++ DP+ + + HA+IGGIVA +VF+ L +
Sbjct: 315 -------------------------NVNDPSPVPSSSSTYHAIIGGIVAFIVFLLLIMLI 349
Query: 389 LLGRYLARHKGTYLTNEAKGAEDAPDADTAIINAEGSQVNAEEKKEYFI 437
LG YL RHKGTYLT+EAKG++DAPDADTAIINAEG Q ++KKEYFI
Sbjct: 350 FLGHYLIRHKGTYLTHEAKGSDDAPDADTAIINAEGGQSGGDDKKEYFI 398
>gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Homo
sapiens]
Length = 442
Score = 342 bits (877), Expect = 4e-94
Identities = 189/415 (45%), Positives = 261/415 (62%), Gaps = 19/415 (4%)
Query: 26 GQFPLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRAS 85
GQ T++VTV+EG A ++C+V+++D++ +Q NP +QT+YF D + L+D+R +L+ S
Sbjct: 44 GQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFS 103
Query: 86 WHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQ 145
EL +S+++VS+SDEG+Y C L+T P + S +TVL P I +EG+ ++
Sbjct: 104 SSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIE 163
Query: 146 LTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVIC 205
+ C SKPA IRWFK + E+K ++E +TV+S L +V + DDGV VIC
Sbjct: 164 VNCTAMASKPATTIRWFKGNTELKGKSEVEEWS---DMYTVTSQLMLKVHKEDDGVPVIC 220
Query: 206 RVDHESLNATPQVAMQVLEIHYTPSVKI---IPSTPFPQEGQPLILTCESKGKPLPEPVL 262
+V+H ++ Q + LE+ Y P V I P +EG L LTCE+ GKP P V
Sbjct: 221 QVEHPAVTGNLQ-TQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVT 279
Query: 263 WTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTL 322
W + E+ P V+SG L I LNKTDNGTYRCEA+N +G++ ++Y+L V+D P T+
Sbjct: 280 WVRVDDEM--PQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTI 337
Query: 323 LPTTIIPSLTTATVTTTVAITTSPTTSATTSSIRDPNALAGQNGPDHALIGGIVAVVVFV 382
P T + TT T TT + I T + + SIR DHA+IGG+VAVVVF
Sbjct: 338 PPPTTTTTTTTTTTTTILTIITD-SRAGEEGSIR---------AVDHAVIGGVVAVVVFA 387
Query: 383 TLCSIFLLGRYLARHKGTYLTNEAKGAEDAPDADTAIINAEGSQVNAEEKKEYFI 437
LC + +LGRY ARHKGTY T+EAKGA+DA DADTAIINAEG Q N+EEKKEYFI
Sbjct: 388 MLCLLIILGRYFARHKGTYFTHEAKGADDAADADTAIINAEGGQNNSEEKKEYFI 442
>gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Homo
sapiens]
Length = 414
Score = 312 bits (799), Expect = 4e-85
Identities = 178/415 (42%), Positives = 247/415 (59%), Gaps = 47/415 (11%)
Query: 26 GQFPLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRAS 85
GQ T++VTV+EG A ++C+V+++D++ +Q NP +QT+YF D + L+D+R +L+ S
Sbjct: 44 GQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFS 103
Query: 86 WHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQ 145
EL +S+++VS+SDEG+Y C L+T P + S +TVL P I +EG+ ++
Sbjct: 104 SSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIE 163
Query: 146 LTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVIC 205
+ C SKPA IRWFK + E+K ++E +TV+S L +V + DDGV VIC
Sbjct: 164 VNCTAMASKPATTIRWFKGNTELKGKSEVEEWS---DMYTVTSQLMLKVHKEDDGVPVIC 220
Query: 206 RVDHESLNATPQVAMQVLEIHYTPSVKI---IPSTPFPQEGQPLILTCESKGKPLPEPVL 262
+V+H ++ Q + LE+ Y P V I P +EG L LTCE+ GKP P V
Sbjct: 221 QVEHPAVTGNLQ-TQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVT 279
Query: 263 WTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTL 322
W + E+ P V+SG L I LNKTDNGTYRCEA+N +G++ ++Y+L V+D
Sbjct: 280 WVRVDDEM--PQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYD----- 332
Query: 323 LPTTIIPSLTTATVTTTVAITTSPTTSATTSSIRDPNALAGQNGPDHALIGGIVAVVVFV 382
+ + SIR DHA+IGG+VAVVVF
Sbjct: 333 ------------------------SRAGEEGSIR---------AVDHAVIGGVVAVVVFA 359
Query: 383 TLCSIFLLGRYLARHKGTYLTNEAKGAEDAPDADTAIINAEGSQVNAEEKKEYFI 437
LC + +LGRY ARHKGTY T+EAKGA+DA DADTAIINAEG Q N+EEKKEYFI
Sbjct: 360 MLCLLIILGRYFARHKGTYFTHEAKGADDAADADTAIINAEGGQNNSEEKKEYFI 414
>gi|21686977 cell adhesion molecule 4 [Homo sapiens]
Length = 388
Score = 236 bits (602), Expect = 3e-62
Identities = 143/413 (34%), Positives = 217/413 (52%), Gaps = 49/413 (11%)
Query: 26 GQFPLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRAS 85
GQ T+NVTV EGG A +TCR+ Q D + + NPA+QTL+F+ +AL+D R +L S
Sbjct: 24 GQEVQTENVTVAEGGVAEITCRLHQYDGSIVVIQNPARQTLFFNGTRALKDERFQLEEFS 83
Query: 86 WHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQ 145
+ I +SD L DEG Y C L+T A LTVL PE P + +EG ++
Sbjct: 84 PRRVRIRLSDARLEDEGGYFCQLYTEDTHHQIATLTVLVAPENPVVE-VREQAVEGGEVE 142
Query: 146 LTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVIC 205
L+C S+PAA +RW+++ KE+K V +E N K ++V+ST+ FRVDR DDG +IC
Sbjct: 143 LSCLVPRSRPAATLRWYRDRKELKGVSSSQE---NGKVWSVASTVRFRVDRKDDGGIIIC 199
Query: 206 RVDHESL-NATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWT 264
+++L + + VL++ Y+P+ +I S +EG L+LTC G P P + W
Sbjct: 200 EAQNQALPSGHSKQTQYVLDVQYSPTARIHASQAVVREGDTLVLTCAVTGNPRPNQIRWN 259
Query: 265 KDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLLP 324
+ L P+R G L + L DNGTY CEA+N G + A YVL+V+D P
Sbjct: 260 RGNESL--PERAEAVGETLTLPGLVSADNGTYTCEASNKHGHARALYVLVVYD------P 311
Query: 325 TTIIPSLTTATVTTTVAITTSPTTSATTSSIRDPNALAGQNGPDHALIGGIVAVVVFVTL 384
++ + T+ +A++GGI+A++VF+ +
Sbjct: 312 GAVVEAQTSV---------------------------------PYAIVGGILALLVFLII 338
Query: 385 CSIFLLGRYLARHKGTYLTNEAKGAEDAPDADTAIINAEGSQVNAEEKKEYFI 437
C + + R KG+YLT+EA G ++ +A A +N + K+E+FI
Sbjct: 339 CVLVGMVWCSVRQKGSYLTHEASGLDEQGEAREAFLNGSDGH---KRKEEFFI 388
>gi|166295173 kin of IRRE like [Homo sapiens]
Length = 757
Score = 96.3 bits (238), Expect = 5e-20
Identities = 92/330 (27%), Positives = 153/330 (46%), Gaps = 26/330 (7%)
Query: 22 KGSQGQF---PLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNR 78
+G+Q +F P Q TVV G A+L C V N + +QW+ KA R
Sbjct: 17 QGTQTRFSQEPADQ--TVVAGQRAVLPC-VLLNYSGIVQWTKDGLALGMGQGLKAWPRYR 73
Query: 79 IELVRASWHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPV 138
+ + A + ++ ++D LSD+ Y C +++ +A LTVL PE +I G PV
Sbjct: 74 V-VGSADAGQYNLEITDAELSDDASYECQATEAALRSRRAKLTVLIPPEDTRIDG--GPV 130
Query: 139 M---EGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKE--EDANRKTFTVSSTLDFR 193
+ G LTC+ +KPAA I WF++ + + E +D R+T TVS L
Sbjct: 131 ILLQAGTPHNLTCRAFNAKPAATIIWFRDGTQQEGAVASTELLKDGKRET-TVSQLLINP 189
Query: 194 VDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESK 253
D D G CR +E++ + + +++ L++H+ P+V + QEG+ ++ TC++
Sbjct: 190 TD-LDIGRVFTCRSMNEAIPSGKETSIE-LDVHHPPTVTLSIEPQTVQEGERVVFTCQAT 247
Query: 254 GKPLPEPVLWTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVL 313
P W K G + D S E N+ + T+ CE N +G ++ ++
Sbjct: 248 ANPEILGYRWAKGGFLIEDAHE---SRYETNVDYSFFTE--PVSCEVHNKVGSTNVSTLV 302
Query: 314 IVHDVPNTLLPTTIIPSLTTATVTTTVAIT 343
VH P + + P TT + + V +T
Sbjct: 303 NVHFAPRIV----VDPKPTTTDIGSDVTLT 328
Score = 58.5 bits (140), Expect = 1e-08
Identities = 68/294 (23%), Positives = 114/294 (38%), Gaps = 32/294 (10%)
Query: 35 TVVEGGTAILTCRVDQNDNTSLQWS-NPAQQTLYFDDKKALRDN--RIELVRASWHELSI 91
T ++GG IL ++ T ++ PA ++F D EL++ E ++
Sbjct: 123 TRIDGGPVILLQAGTPHNLTCRAFNAKPAATIIWFRDGTQQEGAVASTELLKDGKRETTV 182
Query: 92 S---VSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSP--VMEGDLMQL 146
S ++ L +TC + + K L V P ++ P V EG+ +
Sbjct: 183 SQLLINPTDLDIGRVFTCRSMNEAIPSGKETSIELDVHHPPTVTLSIEPQTVQEGERVVF 242
Query: 147 TCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICR 206
TC+ + + RW K I+D S + VD S V C
Sbjct: 243 TCQATANPEILGYRWAKGGFLIEDAH--------------ESRYETNVDYSFFTEPVSCE 288
Query: 207 VDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKD 266
V H + +T ++ +H+ P + + P G + LTC G P P + WTK
Sbjct: 289 V-HNKVGSTN--VSTLVNVHFAPRIVVDPKPTTTDIGSDVTLTCVWVGNP-PLTLTWTK- 343
Query: 267 GGELPDPDRMVVSGRELNILFLNKTDNGTYRCEA-TNTIGQSSAEYVLIVHDVP 319
D + ++ + +L + + + D GTY C A IG + E L V+ P
Sbjct: 344 ----KDSNMVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGPP 393
>gi|221316762 neurotrimin isoform 4 [Homo sapiens]
Length = 316
Score = 89.4 bits (220), Expect = 6e-18
Identities = 95/321 (29%), Positives = 145/321 (45%), Gaps = 32/321 (9%)
Query: 1 MFVLFLCNLSLVPAAASKNKVKGSQGQFPLTQ-NVTVVEGGTAILTCRVDQNDNTSLQWS 59
+ V+ L L LVP V+ FP NVTV +G +A L C +D N T + W
Sbjct: 14 LVVVSLRLLFLVPTGVP---VRSGDATFPKAMDNVTVRQGESATLRCTID-NRVTRVAWL 69
Query: 60 NPAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVSLSDEGQYTCSLFT-MPVKTSKA 118
N + LY + K D R+ L+ + + SI + +V + DEG YTCS+ T KTS+
Sbjct: 70 NRST-ILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRV 128
Query: 119 YLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEED 178
+L V P+ +IS S + EG+ + LTC +G +P + W K V ++ E++
Sbjct: 129 HLIVQVSPKIVEISSDIS-INEGNNISLTCIATG-RPEPTVTW--RHISPKAVGFVSEDE 184
Query: 179 -ANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPST 237
+ T + D+ S+D A P V + ++Y P + T
Sbjct: 185 YLEIQGITREQSGDYECSASND-------------VAAPVVRRVKVTVNYPPYISEAKGT 231
Query: 238 PFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMV-VSGREL--NILFLN--KTD 292
P GQ L CE+ P E W KD L + + V V R ++F N + D
Sbjct: 232 GVP-VGQKGTLQCEASAVPSAE-FQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHD 289
Query: 293 NGTYRCEATNTIGQSSAEYVL 313
G Y C A+N +G ++A +L
Sbjct: 290 YGNYTCVASNKLGHTNASIML 310
Score = 35.0 bits (79), Expect = 0.13
Identities = 33/126 (26%), Positives = 50/126 (39%), Gaps = 8/126 (6%)
Query: 194 VDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESK 253
VD D+G C V ++ T +V L + +P + I S EG + LTC +
Sbjct: 105 VDVYDEG-PYTCSVQTDNHPKTSRVH---LIVQVSPKIVEISSDISINEGNNISLTCIAT 160
Query: 254 GKPLPEPVLWTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVL 313
G+P P V W P V L I + + +G Y C A+N + V
Sbjct: 161 GRPEPT-VTWRHIS---PKAVGFVSEDEYLEIQGITREQSGDYECSASNDVAAPVVRRVK 216
Query: 314 IVHDVP 319
+ + P
Sbjct: 217 VTVNYP 222
>gi|221316757 neurotrimin isoform 3 [Homo sapiens]
Length = 355
Score = 89.4 bits (220), Expect = 6e-18
Identities = 95/321 (29%), Positives = 145/321 (45%), Gaps = 32/321 (9%)
Query: 1 MFVLFLCNLSLVPAAASKNKVKGSQGQFPLTQ-NVTVVEGGTAILTCRVDQNDNTSLQWS 59
+ V+ L L LVP V+ FP NVTV +G +A L C +D N T + W
Sbjct: 14 LVVVSLRLLFLVPTGVP---VRSGDATFPKAMDNVTVRQGESATLRCTID-NRVTRVAWL 69
Query: 60 NPAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVSLSDEGQYTCSLFT-MPVKTSKA 118
N + LY + K D R+ L+ + + SI + +V + DEG YTCS+ T KTS+
Sbjct: 70 NRST-ILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRV 128
Query: 119 YLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEED 178
+L V P+ +IS S + EG+ + LTC +G +P + W K V ++ E++
Sbjct: 129 HLIVQVSPKIVEISSDIS-INEGNNISLTCIATG-RPEPTVTW--RHISPKAVGFVSEDE 184
Query: 179 -ANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPST 237
+ T + D+ S+D A P V + ++Y P + T
Sbjct: 185 YLEIQGITREQSGDYECSASND-------------VAAPVVRRVKVTVNYPPYISEAKGT 231
Query: 238 PFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMV-VSGREL--NILFLN--KTD 292
P GQ L CE+ P E W KD L + + V V R ++F N + D
Sbjct: 232 GVP-VGQKGTLQCEASAVPSAE-FQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHD 289
Query: 293 NGTYRCEATNTIGQSSAEYVL 313
G Y C A+N +G ++A +L
Sbjct: 290 YGNYTCVASNKLGHTNASIML 310
Score = 35.0 bits (79), Expect = 0.13
Identities = 33/126 (26%), Positives = 50/126 (39%), Gaps = 8/126 (6%)
Query: 194 VDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESK 253
VD D+G C V ++ T +V L + +P + I S EG + LTC +
Sbjct: 105 VDVYDEG-PYTCSVQTDNHPKTSRVH---LIVQVSPKIVEISSDISINEGNNISLTCIAT 160
Query: 254 GKPLPEPVLWTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVL 313
G+P P V W P V L I + + +G Y C A+N + V
Sbjct: 161 GRPEPT-VTWRHIS---PKAVGFVSEDEYLEIQGITREQSGDYECSASNDVAAPVVRRVK 216
Query: 314 IVHDVP 319
+ + P
Sbjct: 217 VTVNYP 222
>gi|112789532 poliovirus receptor related 2 isoform delta precursor
[Homo sapiens]
Length = 538
Score = 89.4 bits (220), Expect = 6e-18
Identities = 76/267 (28%), Positives = 112/267 (41%), Gaps = 14/267 (5%)
Query: 84 ASWHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVM--EG 141
A + ++++ +++ DEG YTC T P K S +T L V KP+ + V +
Sbjct: 118 AELQDATLALHGLTVEDEGNYTCEFATFP-KGSVRGMTWLRVIAKPKNQAEAQKVTFSQD 176
Query: 142 DLMQLTCKTSGSKPAADIRWFKN-DKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDG 200
C + +P A I W + D E K+ + T TV+S DG
Sbjct: 177 PTTVALCISKEGRPPARISWLSSLDWEAKETQV---SGTLAGTVTVTSRFTLVPSGRADG 233
Query: 201 VAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQP-LILTCESKGKPLPE 259
V V C+V+HES P + L + Y P V I G+ L+C+ + P P
Sbjct: 234 VTVTCKVEHESFEE-PALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPT 292
Query: 260 PVLWTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
W+ G P V G +L I ++ N T+ C TN +G AE V+ V + P
Sbjct: 293 GYDWSTTSGTFPTS--AVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETP 350
Query: 320 NTL---LPTTIIPSLTTATVTTTVAIT 343
NT II + A + T VA T
Sbjct: 351 NTAGAGATGGIIGGIIAAIIATAVAAT 377
>gi|7705413 neurotrimin isoform 1 [Homo sapiens]
Length = 344
Score = 89.4 bits (220), Expect = 6e-18
Identities = 95/321 (29%), Positives = 145/321 (45%), Gaps = 32/321 (9%)
Query: 1 MFVLFLCNLSLVPAAASKNKVKGSQGQFPLTQ-NVTVVEGGTAILTCRVDQNDNTSLQWS 59
+ V+ L L LVP V+ FP NVTV +G +A L C +D N T + W
Sbjct: 14 LVVVSLRLLFLVPTGVP---VRSGDATFPKAMDNVTVRQGESATLRCTID-NRVTRVAWL 69
Query: 60 NPAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVSLSDEGQYTCSLFT-MPVKTSKA 118
N + LY + K D R+ L+ + + SI + +V + DEG YTCS+ T KTS+
Sbjct: 70 NRST-ILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRV 128
Query: 119 YLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEED 178
+L V P+ +IS S + EG+ + LTC +G +P + W K V ++ E++
Sbjct: 129 HLIVQVSPKIVEISSDIS-INEGNNISLTCIATG-RPEPTVTW--RHISPKAVGFVSEDE 184
Query: 179 -ANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPST 237
+ T + D+ S+D A P V + ++Y P + T
Sbjct: 185 YLEIQGITREQSGDYECSASND-------------VAAPVVRRVKVTVNYPPYISEAKGT 231
Query: 238 PFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMV-VSGREL--NILFLN--KTD 292
P GQ L CE+ P E W KD L + + V V R ++F N + D
Sbjct: 232 GVP-VGQKGTLQCEASAVPSAE-FQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHD 289
Query: 293 NGTYRCEATNTIGQSSAEYVL 313
G Y C A+N +G ++A +L
Sbjct: 290 YGNYTCVASNKLGHTNASIML 310
Score = 35.0 bits (79), Expect = 0.13
Identities = 33/126 (26%), Positives = 50/126 (39%), Gaps = 8/126 (6%)
Query: 194 VDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESK 253
VD D+G C V ++ T +V L + +P + I S EG + LTC +
Sbjct: 105 VDVYDEG-PYTCSVQTDNHPKTSRVH---LIVQVSPKIVEISSDISINEGNNISLTCIAT 160
Query: 254 GKPLPEPVLWTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVL 313
G+P P V W P V L I + + +G Y C A+N + V
Sbjct: 161 GRPEPT-VTWRHIS---PKAVGFVSEDEYLEIQGITREQSGDYECSASNDVAAPVVRRVK 216
Query: 314 IVHDVP 319
+ + P
Sbjct: 217 VTVNYP 222
>gi|51593098 class-I MHC-restricted T cell associated molecule [Homo
sapiens]
Length = 393
Score = 87.8 bits (216), Expect = 2e-17
Identities = 58/190 (30%), Positives = 90/190 (47%), Gaps = 3/190 (1%)
Query: 31 TQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELS 90
T+ +TV EG T L C N+SLQW P+ T++ ++ AL++++ +L+ S ++LS
Sbjct: 23 TETITVEEGQTLTLKCVTSLRKNSSLQWLTPSGFTIFLNEYPALKNSKYQLLHHSANQLS 82
Query: 91 ISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEG-DLMQLTCK 149
I+V +V+L DEG Y C ++ V T + + VL P KP + G + + L C
Sbjct: 83 ITVPNVTLQDEGVYKCLHYSDSVSTKEVKVIVLATPFKPILEASVIRKQNGEEHVVLMCS 142
Query: 150 TSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDH 209
T SKP I W + L E + + K +STL + V C + H
Sbjct: 143 TMRSKPPPQITWLLGNSMEVSGGTLHEFETDGKKCNTTSTLIIHTYGKNS--TVDCIIRH 200
Query: 210 ESLNATPQVA 219
L VA
Sbjct: 201 RGLQGRKLVA 210
>gi|115298665 neurotrimin isoform 2 [Homo sapiens]
Length = 344
Score = 87.8 bits (216), Expect = 2e-17
Identities = 89/301 (29%), Positives = 137/301 (45%), Gaps = 29/301 (9%)
Query: 21 VKGSQGQFPLTQ-NVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRI 79
V+ FP NVTV +G +A L C +D N T + W N + LY + K D R+
Sbjct: 31 VRSGDATFPKAMDNVTVRQGESATLRCTID-NRVTRVAWLNRST-ILYAGNDKWCLDPRV 88
Query: 80 ELVRASWHELSISVSDVSLSDEGQYTCSLFT-MPVKTSKAYLTVLGVPEKPQISGFSSPV 138
L+ + + SI + +V + DEG YTCS+ T KTS+ +L V P+ +IS S +
Sbjct: 89 VLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEISSDIS-I 147
Query: 139 MEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEED-ANRKTFTVSSTLDFRVDRS 197
EG+ + LTC +G +P + W K V ++ E++ + T + D+ S
Sbjct: 148 NEGNNISLTCIATG-RPEPTVTW--RHISPKAVGFVSEDEYLEIQGITREQSGDYECSAS 204
Query: 198 DDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPL 257
+D A P V + ++Y P + T P GQ L CE+ P
Sbjct: 205 ND-------------VAAPVVRRVKVTVNYPPYISEAKGTGVP-VGQKGTLQCEASAVPS 250
Query: 258 PEPVLWTKDGGELPDPDRMV-VSGREL--NILFLN--KTDNGTYRCEATNTIGQSSAEYV 312
E W KD L + + V V R ++F N + D G Y C A+N +G ++A +
Sbjct: 251 AE-FQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLGHTNASIM 309
Query: 313 L 313
L
Sbjct: 310 L 310
Score = 35.0 bits (79), Expect = 0.13
Identities = 33/126 (26%), Positives = 50/126 (39%), Gaps = 8/126 (6%)
Query: 194 VDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESK 253
VD D+G C V ++ T +V L + +P + I S EG + LTC +
Sbjct: 105 VDVYDEG-PYTCSVQTDNHPKTSRVH---LIVQVSPKIVEISSDISINEGNNISLTCIAT 160
Query: 254 GKPLPEPVLWTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVL 313
G+P P V W P V L I + + +G Y C A+N + V
Sbjct: 161 GRPEPT-VTWRHIS---PKAVGFVSEDEYLEIQGITREQSGDYECSASNDVAAPVVRRVK 216
Query: 314 IVHDVP 319
+ + P
Sbjct: 217 VTVNYP 222
>gi|11386199 poliovirus receptor-related 3 [Homo sapiens]
Length = 549
Score = 87.8 bits (216), Expect = 2e-17
Identities = 94/396 (23%), Positives = 168/396 (42%), Gaps = 39/396 (9%)
Query: 26 GQFPLTQNVTVVEGGTAILTCRVDQNDN-TSLQWSN---PAQQTL------YFDDKKALR 75
G + +VT V G L C ++ N+ T + W + QT+ Y +
Sbjct: 58 GPIIVEPHVTAVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEY 117
Query: 76 DNRIELVRASWHELSISVSDVSLSDEGQYTCSLFTMPVKT--SKAYLTVLGVPEKPQISG 133
R+ S ++ +I++ ++ SD G+Y C T P+ S +TVL P I G
Sbjct: 118 QGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKG 177
Query: 134 FSSPVMEG-DLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDF 192
S + G + + C + KP A I W + ++ +++ N +T T+ S
Sbjct: 178 PDSLIDGGNETVAAICIAATGKPVAHIDW---EGDLGEMESTTTSFPN-ETATIISQYKL 233
Query: 193 RVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLI-LTCE 251
R G + C V H +L + + +L+I Y P V + G+ + L C
Sbjct: 234 FPTRFARGRRITCVVKHPALEKDIRYSF-ILDIQYAPEVSVTGYDGNWFVGRKGVNLKCN 292
Query: 252 SKGKPLPEPVLWTKDGGELPDPDRMVVSGRELNILF-LNKTDNGTYRCEATNTIGQSSAE 310
+ P P +W++ G+ PD ++ S L+ + L +G Y C+ TN++GQ S +
Sbjct: 293 ADANPPPFKSVWSRLDGQWPDG--LLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQ 350
Query: 311 YVLIVHDVPNTLLPTTIIPSLTTATVTTTVAITTS-----PTTSATTSSIRDPNALAGQN 365
V+ + D P T TT+ P++ T + + P +T ++I+D
Sbjct: 351 KVIYISDPPTT---TTLQPTIQWHPSTADIEDLATEPKKLPFPLSTLATIKDDTIA---- 403
Query: 366 GPDHALIGGIVAVVVFVTLCSIFLLGRYLARHKGTY 401
+I +V +F+ L S+ L G + R + T+
Sbjct: 404 ----TIIASVVGGALFIVLVSV-LAGIFCYRRRRTF 434
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 87.4 bits (215), Expect = 2e-17
Identities = 86/322 (26%), Positives = 128/322 (39%), Gaps = 35/322 (10%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQW-SNPAQQTLYFDDKKALRDNRIELVRASWHELS 90
Q+ V G T TCR + N + W N + ++ D + L D+ +
Sbjct: 253 QDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDG-----------T 301
Query: 91 ISVSDVSLSDEGQYTCSLFTM--PVKTSKAYLTVLGVPEKPQ--ISGFSSPVMEGDLMQL 146
+ + + +D+G Y C + VKT + L G P +P I ++ V+ G+ + L
Sbjct: 302 LMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTL 361
Query: 147 TCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICR 206
C +G P I W + D+ V R T S L + D C
Sbjct: 362 ECSATGHPPPR-ISWTRGDRTPLPVD-------PRVNITPSGGLYIQNVVQGDSGEYACS 413
Query: 207 VDH--ESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWT 264
+ +S++AT + +Q L P + P EGQ + CE+KG P P + WT
Sbjct: 414 ATNNIDSVHATAFIIVQAL-----PQFTVTPQDRVVIEGQTVDFQCEAKGNP-PPVIAWT 467
Query: 265 KDGGELP-DPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLL 323
K G +L D +V+S L I + D G Y C+A N IG L V P
Sbjct: 468 KGGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQ--PRVTP 525
Query: 324 PTTIIPSLTTATVTTTVAITTS 345
IPS TT V V + S
Sbjct: 526 VFASIPSDTTVEVGANVQLPCS 547
Score = 72.0 bits (175), Expect = 1e-12
Identities = 85/339 (25%), Positives = 138/339 (40%), Gaps = 39/339 (11%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSI 91
QN V+ G + L C + + W+ + L D R+ + + +
Sbjct: 349 QNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDP-------RVNITPSG----GL 397
Query: 92 SVSDVSLSDEGQYTCSLFT-MPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKT 150
+ +V D G+Y CS + + A++ V +P+ ++ V+EG + C+
Sbjct: 398 YIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQFT-VTPQDRVVIEGQTVDFQCEA 456
Query: 151 SGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHE 210
G+ P I W K ++ +R+ +SS R+ GVA+ + +E
Sbjct: 457 KGNPPPV-IAWTKGGSQLS---------VDRRHLVLSSGT-LRIS----GVALHDQGQYE 501
Query: 211 S-----LNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTK 265
+ + VA ++ TP IPS + G + L C S+G+P P + W K
Sbjct: 502 CQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPA-ITWNK 560
Query: 266 DGGELPDPDRMVVSGRE-LNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVH--DVPNTL 322
DG ++ + + +S L I + D G Y C A NTIG +S VL V+ DV
Sbjct: 561 DGVQVTESGKFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSVNVPDVSRNG 620
Query: 323 LPTTIIPSLTTATVTTTVAITTSPTTSATTSSIRDPNAL 361
P + S+ A T AI S T S R PN L
Sbjct: 621 DP-FVATSIVEAIATVDRAI-NSTRTHLFDSRPRSPNDL 657
Score = 43.5 bits (101), Expect = 4e-04
Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 6/123 (4%)
Query: 229 PSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGEL---PDPDRMVVSGRELNI 285
P + P G + TC ++G P PE ++W ++ EL D ++ L I
Sbjct: 246 PRITSEPQDADVTSGNTVYFTCRAEGNPKPE-IIWLRNNNELSMKTDSRLNLLDDGTLMI 304
Query: 286 LFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLLPTTII-PSLTTATVTTTVAITT 344
+TD G Y+C A N G+ + V + + + PT +I P T V +V +
Sbjct: 305 QNTQETDQGIYQCMAKNVAGEVKTQEVTLRY-FGSPARPTFVIQPQNTEVLVGESVTLEC 363
Query: 345 SPT 347
S T
Sbjct: 364 SAT 366
>gi|4505505 opioid binding protein/cell adhesion molecule-like
isoform a preproprotein [Homo sapiens]
Length = 345
Score = 87.0 bits (214), Expect = 3e-17
Identities = 98/324 (30%), Positives = 148/324 (45%), Gaps = 37/324 (11%)
Query: 1 MFVLFLCNLSLVPAAASKNKVKGSQGQFPLTQ-NVTVVEGGTAILTCRVDQNDNTSLQWS 59
+ V+ L L LVP V+ FP NVTV +G +A L C +D T + W
Sbjct: 14 LVVVSLRLLFLVPTGVP---VRSGDATFPKAMDNVTVRQGESATLRCTIDDRV-TRVAWL 69
Query: 60 NPAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVSLSDEGQYTCSLFT-MPVKTSKA 118
N + LY + K D R+ ++ + + SI + +V + DEG YTCS+ T KTS+
Sbjct: 70 NRST-ILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRV 128
Query: 119 YLTVLGVPEKPQISGFSS--PVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKE 176
+L ++ VP PQI SS V EG + L C G +P + W +K+ +
Sbjct: 129 HL-IVQVP--PQIMNISSDITVNEGSSVTLLCLAIG-RPEPTVTW--RHLSVKEGQGFVS 182
Query: 177 EDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLN--ATPQVAMQVLEIHYTPSVKII 234
ED + +S D + D+S + + +LN A P V + ++Y P +
Sbjct: 183 ED---EYLEIS---DIKRDQSGE-------YECSALNDVAAPDVRKVKITVNYPPYISKA 229
Query: 235 PSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELP---DPDRMVVSGRELNILFLN-- 289
+T GQ IL+CE+ P+ E W K+ L D R+ GR + F N
Sbjct: 230 KNTGV-SVGQKGILSCEASAVPMAE-FQWFKEETRLATGLDGMRIENKGRMSTLTFFNVS 287
Query: 290 KTDNGTYRCEATNTIGQSSAEYVL 313
+ D G Y C ATN +G ++A L
Sbjct: 288 EKDYGNYTCVATNKLGNTNASITL 311
Score = 32.7 bits (73), Expect = 0.67
Identities = 37/141 (26%), Positives = 53/141 (37%), Gaps = 15/141 (10%)
Query: 183 TFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQE 242
T T S + VD D+G C V ++ T +V L + P + I S E
Sbjct: 94 TPTQYSIMIQNVDVYDEG-PYTCSVQTDNHPKTSRVH---LIVQVPPQIMNISSDITVNE 149
Query: 243 GQPLILTCESKGKPLPEPVLW----TKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRC 298
G + L C + G+P P V W K+G D L I + + +G Y C
Sbjct: 150 GSSVTLLCLAIGRPEPT-VTWRHLSVKEGQGFVSEDEY------LEISDIKRDQSGEYEC 202
Query: 299 EATNTIGQSSAEYVLIVHDVP 319
A N + V I + P
Sbjct: 203 SALNDVAAPDVRKVKITVNYP 223
>gi|45594240 limbic system-associated membrane protein [Homo
sapiens]
Length = 338
Score = 87.0 bits (214), Expect = 3e-17
Identities = 87/321 (27%), Positives = 140/321 (43%), Gaps = 51/321 (15%)
Query: 9 LSLVPAAASKNKVKGSQGQFPLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYF 68
L L+P V ++G T N+TV +G TAIL C V+ N+ + W N +
Sbjct: 20 LCLLPTGLPVRSVDFNRG----TDNITVRQGDTAILRCVVEDK-NSKVAWLNRSGIIFAG 74
Query: 69 DDKKALRDNRIELVRASWHELSISVSDVSLSDEGQYTCSLFTM-PVKTSKAYLTVLGVPE 127
DK +L D R+EL + E S+ + V + DEG YTCS+ T KTS+ YL ++ VP
Sbjct: 75 HDKWSL-DPRVELEKRHSLEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYL-IVQVP- 131
Query: 128 KPQISGFSSPVM--EGDLMQLTCKTSGSKPAADIRW---------FKNDKEIKDVKYLKE 176
P+IS SS V EG + L C +G +P I W F+ ++E ++ +
Sbjct: 132 -PKISNISSDVTVNEGSNVTLVCMANG-RPEPVITWRHLTPTGREFEGEEEYLEILGITR 189
Query: 177 EDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPS 236
E + + C+ +E +A V + ++Y P++ S
Sbjct: 190 EQSGKYE---------------------CKAANEVSSA--DVKQVKVTVNYPPTITESKS 226
Query: 237 TPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGRE----LNILFLNKTD 292
G+ L CE+ P P+ W +D + + + + E L + + +
Sbjct: 227 NE-ATTGRQASLKCEASAVPAPD-FEWYRDDTRINSANGLEIKSTEGQSSLTVTNVTEEH 284
Query: 293 NGTYRCEATNTIGQSSAEYVL 313
G Y C A N +G ++A VL
Sbjct: 285 YGNYTCVAANKLGVTNASLVL 305
Score = 43.5 bits (101), Expect = 4e-04
Identities = 37/134 (27%), Positives = 58/134 (43%), Gaps = 16/134 (11%)
Query: 193 RVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCES 252
+VD D+G + C V + T QV L + P + I S EG + L C +
Sbjct: 100 KVDVYDEG-SYTCSVQTQHEPKTSQV---YLIVQVPPKISNISSDVTVNEGSNVTLVCMA 155
Query: 253 KGKPLPEPVL-W---TKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSS 308
G+P EPV+ W T G E + L IL + + +G Y C+A N + +
Sbjct: 156 NGRP--EPVITWRHLTPTGREFEGEEEY------LEILGITREQSGKYECKAANEVSSAD 207
Query: 309 AEYVLIVHDVPNTL 322
+ V + + P T+
Sbjct: 208 VKQVKVTVNYPPTI 221
>gi|59939900 opioid binding protein/cell adhesion molecule-like
isoform b preproprotein [Homo sapiens]
Length = 338
Score = 85.5 bits (210), Expect = 9e-17
Identities = 92/304 (30%), Positives = 140/304 (46%), Gaps = 34/304 (11%)
Query: 21 VKGSQGQFPLTQ-NVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRI 79
V+ FP NVTV +G +A L C +D T + W N + LY + K D R+
Sbjct: 24 VRSGDATFPKAMDNVTVRQGESATLRCTIDDRV-TRVAWLNRST-ILYAGNDKWSIDPRV 81
Query: 80 ELVRASWHELSISVSDVSLSDEGQYTCSLFT-MPVKTSKAYLTVLGVPEKPQISGFSS-- 136
++ + + SI + +V + DEG YTCS+ T KTS+ +L ++ VP PQI SS
Sbjct: 82 IILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHL-IVQVP--PQIMNISSDI 138
Query: 137 PVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDR 196
V EG + L C G +P + W +K+ + ED + +S D + D+
Sbjct: 139 TVNEGSSVTLLCLAIG-RPEPTVTW--RHLSVKEGQGFVSED---EYLEIS---DIKRDQ 189
Query: 197 SDDGVAVICRVDHESLN--ATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKG 254
S + + +LN A P V + ++Y P + +T GQ IL+CE+
Sbjct: 190 SGE-------YECSALNDVAAPDVRKVKITVNYPPYISKAKNTGV-SVGQKGILSCEASA 241
Query: 255 KPLPEPVLWTKDGGELP---DPDRMVVSGRELNILFLN--KTDNGTYRCEATNTIGQSSA 309
P+ E W K+ L D R+ GR + F N + D G Y C ATN +G ++A
Sbjct: 242 VPMAE-FQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA 300
Query: 310 EYVL 313
L
Sbjct: 301 SITL 304
Score = 32.7 bits (73), Expect = 0.67
Identities = 37/141 (26%), Positives = 53/141 (37%), Gaps = 15/141 (10%)
Query: 183 TFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQE 242
T T S + VD D+G C V ++ T +V L + P + I S E
Sbjct: 87 TPTQYSIMIQNVDVYDEG-PYTCSVQTDNHPKTSRVH---LIVQVPPQIMNISSDITVNE 142
Query: 243 GQPLILTCESKGKPLPEPVLW----TKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRC 298
G + L C + G+P P V W K+G D L I + + +G Y C
Sbjct: 143 GSSVTLLCLAIGRPEPT-VTWRHLSVKEGQGFVSEDEY------LEISDIKRDQSGEYEC 195
Query: 299 EATNTIGQSSAEYVLIVHDVP 319
A N + V I + P
Sbjct: 196 SALNDVAAPDVRKVKITVNYP 216
>gi|4507875 vascular cell adhesion molecule 1 isoform a precursor
[Homo sapiens]
Length = 739
Score = 85.1 bits (209), Expect = 1e-16
Identities = 71/246 (28%), Positives = 119/246 (48%), Gaps = 22/246 (8%)
Query: 90 SISVSDVSLSDEGQYTCSLFTMPVKTSKAY-LTVLGVPEKPQISGFSSPVMEGDLMQLTC 148
+++++ VS +E Y C+ K K + + P+ P+I S P+ G + + C
Sbjct: 79 TLTMNPVSFGNEHSYLCTATCESRKLEKGIQVEIYSFPKDPEIH-LSGPLEAGKPITVKC 137
Query: 149 KTSGSKP--AADIRWFKNDKEIKDVKYLKEEDANRKTF-TVSSTLDFRVDRSDDGVAVIC 205
+ P +I K D +K ++L EDA+RK+ T S + F D G ++C
Sbjct: 138 SVADVYPFDRLEIDLLKGDHLMKSQEFL--EDADRKSLETKSLEVTFTPVIEDIGKVLVC 195
Query: 206 R----VDHESLNATPQVAMQVLEIHYTPSVKII---PSTPFPQEGQPLILTCESKGKPLP 258
R +D T + A++ L+++ +P +I PST QEG + +TC S+G P P
Sbjct: 196 RAKLHIDEMDSVPTVRQAVKELQVYISPKNTVISVNPSTKL-QEGGSVTMTCSSEGLPAP 254
Query: 259 EPVLWTK--DGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVH 316
E + W+K D G L + + L ++ + D+G Y CE N IG++ E LIV
Sbjct: 255 E-IFWSKKLDNGNL----QHLSGNATLTLIAMRMEDSGIYVCEGVNLIGKNRKEVELIVQ 309
Query: 317 DVPNTL 322
+ P T+
Sbjct: 310 EKPFTV 315
Score = 78.2 bits (191), Expect = 1e-14
Identities = 74/316 (23%), Positives = 137/316 (43%), Gaps = 34/316 (10%)
Query: 39 GGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVSL 98
G + +LTC V ++ S W L VR+ ++++S VS
Sbjct: 328 GDSVMLTCSVMGCESPSFSWRTQIDSPLSGK------------VRSEGTNSTLTLSPVSF 375
Query: 99 SDEGQYTCSLFTMPVKTSKAYLTVL-GVPEKPQISGFSSPVMEGDLMQLTCKTSGSKPA- 156
+E Y C++ K K L P P+I S ++ G + ++CK P
Sbjct: 376 ENEHSYLCTVTCGHKKLEKGIQVELYSFPRDPEIE-MSGGLVNGSSVTVSCKVPSVYPLD 434
Query: 157 -ADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICR----VDHES 211
+I K + ++++++L++ D + S + F D G A++C+ +D
Sbjct: 435 RLEIELLKGETILENIEFLEDTDM-KSLENKSLEMTFIPTIEDTGKALVCQAKLHIDDME 493
Query: 212 LNATPQVAMQVLEIHYTP---SVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGG 268
+ + Q L ++ P +V + PS+ +EG + +TC S+G P P+ +LW++
Sbjct: 494 FEPKQRQSTQTLYVNVAPRDTTVLVSPSSIL-EEGSSVNMTCLSQGFPAPK-ILWSR--- 548
Query: 269 ELPDPDRMVVS-GRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVH----DVPNTLL 323
+LP+ + +S L ++ D+G Y CE N G+S E LI+ D+ T
Sbjct: 549 QLPNGELQPLSENATLTLISTKMEDSGVYLCEGINQAGRSRKEVELIIQVTPKDIKLTAF 608
Query: 324 PTTIIPSLTTATVTTT 339
P+ + T ++ T
Sbjct: 609 PSESVKEGDTVIISCT 624
Score = 37.7 bits (86), Expect = 0.021
Identities = 51/193 (26%), Positives = 77/193 (39%), Gaps = 30/193 (15%)
Query: 135 SSPVMEGDLMQLTCKTSGSKPAADIRWFKN--DKEIKDVKYLKEEDANRKTFTVSSTLDF 192
SS + EG + +TC + G PA I W + + E++ + + T T+ ST
Sbjct: 521 SSILEEGSSVNMTCLSQGF-PAPKILWSRQLPNGELQPL-------SENATLTLIST--- 569
Query: 193 RVDRSDDGVAVICRVDHESLNATPQVAMQV-LEIHYTPSVKIIPSTPFP----QEGQPLI 247
+ +D +C E +N + +V L I TP K I T FP +EG +I
Sbjct: 570 ---KMEDSGVYLC----EGINQAGRSRKEVELIIQVTP--KDIKLTAFPSESVKEGDTVI 620
Query: 248 LTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQS 307
++C +PE + K E D + G I D G Y CE+ N +G
Sbjct: 621 ISCTCGN--VPETWIILKKKAETGDTVLKSIDGA-YTIRKAQLKDAGVYECESKNKVGSQ 677
Query: 308 SAEYVLIVHDVPN 320
L V N
Sbjct: 678 LRSLTLDVQGREN 690
>gi|18201909 vascular cell adhesion molecule 1 isoform b precursor
[Homo sapiens]
Length = 647
Score = 82.8 bits (203), Expect = 6e-16
Identities = 70/243 (28%), Positives = 116/243 (47%), Gaps = 22/243 (9%)
Query: 90 SISVSDVSLSDEGQYTCSLFTMPVKTSKAY-LTVLGVPEKPQISGFSSPVMEGDLMQLTC 148
+++++ VS +E Y C+ K K + + P+ P+I S P+ G + + C
Sbjct: 79 TLTMNPVSFGNEHSYLCTATCESRKLEKGIQVEIYSFPKDPEIH-LSGPLEAGKPITVKC 137
Query: 149 KTSGSKP--AADIRWFKNDKEIKDVKYLKEEDANRKTF-TVSSTLDFRVDRSDDGVAVIC 205
+ P +I K D +K ++L EDA+RK+ T S + F D G ++C
Sbjct: 138 SVADVYPFDRLEIDLLKGDHLMKSQEFL--EDADRKSLETKSLEVTFTPVIEDIGKVLVC 195
Query: 206 R----VDHESLNATPQVAMQVLEIHYTPSVKII---PSTPFPQEGQPLILTCESKGKPLP 258
R +D T + A++ L+++ +P +I PST QEG + +TC S+G P P
Sbjct: 196 RAKLHIDEMDSVPTVRQAVKELQVYISPKNTVISVNPSTKL-QEGGSVTMTCSSEGLPAP 254
Query: 259 EPVLWTK--DGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVH 316
E + W+K D G L + + L ++ + D+G Y CE N IG++ E LIV
Sbjct: 255 E-IFWSKKLDNGNL----QHLSGNATLTLIAMRMEDSGIYVCEGVNLIGKNRKEVELIVQ 309
Query: 317 DVP 319
P
Sbjct: 310 AFP 312
Score = 75.1 bits (183), Expect = 1e-13
Identities = 72/317 (22%), Positives = 139/317 (43%), Gaps = 37/317 (11%)
Query: 38 EGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVS 97
EGG+ +TC + + WS K L + ++ + + ++++ +
Sbjct: 238 EGGSVTMTCSSEGLPAPEIFWS------------KKLDNGNLQHLSGN---ATLTLIAMR 282
Query: 98 LSDEGQYTCSLFTMPVKTSKAY-LTVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGSKPA 156
+ D G Y C + K K L V P P+I S ++ G + ++CK P
Sbjct: 283 MEDSGIYVCEGVNLIGKNRKEVELIVQAFPRDPEIE-MSGGLVNGSSVTVSCKVPSVYPL 341
Query: 157 --ADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICR----VDHE 210
+I K + ++++++L++ D + S + F D G A++C+ +D
Sbjct: 342 DRLEIELLKGETILENIEFLEDTDM-KSLENKSLEMTFIPTIEDTGKALVCQAKLHIDDM 400
Query: 211 SLNATPQVAMQVLEIHYTP---SVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDG 267
+ + Q L ++ P +V + PS+ +EG + +TC S+G P P+ +LW++
Sbjct: 401 EFEPKQRQSTQTLYVNVAPRDTTVLVSPSSIL-EEGSSVNMTCLSQGFPAPK-ILWSR-- 456
Query: 268 GELPDPDRMVVS-GRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVH----DVPNTL 322
+LP+ + +S L ++ D+G Y CE N G+S E LI+ D+ T
Sbjct: 457 -QLPNGELQPLSENATLTLISTKMEDSGVYLCEGINQAGRSRKEVELIIQVTPKDIKLTA 515
Query: 323 LPTTIIPSLTTATVTTT 339
P+ + T ++ T
Sbjct: 516 FPSESVKEGDTVIISCT 532
Score = 37.7 bits (86), Expect = 0.021
Identities = 51/193 (26%), Positives = 77/193 (39%), Gaps = 30/193 (15%)
Query: 135 SSPVMEGDLMQLTCKTSGSKPAADIRWFKN--DKEIKDVKYLKEEDANRKTFTVSSTLDF 192
SS + EG + +TC + G PA I W + + E++ + + T T+ ST
Sbjct: 429 SSILEEGSSVNMTCLSQGF-PAPKILWSRQLPNGELQPL-------SENATLTLIST--- 477
Query: 193 RVDRSDDGVAVICRVDHESLNATPQVAMQV-LEIHYTPSVKIIPSTPFP----QEGQPLI 247
+ +D +C E +N + +V L I TP K I T FP +EG +I
Sbjct: 478 ---KMEDSGVYLC----EGINQAGRSRKEVELIIQVTP--KDIKLTAFPSESVKEGDTVI 528
Query: 248 LTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQS 307
++C +PE + K E D + G I D G Y CE+ N +G
Sbjct: 529 ISCTCGN--VPETWIILKKKAETGDTVLKSIDGA-YTIRKAQLKDAGVYECESKNKVGSQ 585
Query: 308 SAEYVLIVHDVPN 320
L V N
Sbjct: 586 LRSLTLDVQGREN 598
>gi|157819143 IgLON family member 5 [Homo sapiens]
Length = 336
Score = 82.8 bits (203), Expect = 6e-16
Identities = 81/303 (26%), Positives = 126/303 (41%), Gaps = 57/303 (18%)
Query: 33 NVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSIS 92
N TV EG A L+C +D++ T + W N + LY + + D R+ L+ + E SI
Sbjct: 41 NYTVCEGDNATLSCFIDEHV-TRVAWLNRSN-ILYAGNDRWTSDPRVRLLINTPEEFSIL 98
Query: 93 VSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVM--EGDLMQLTCKT 150
+++V L DEG YTCS T + ++ VP + I SSPV EG + L C
Sbjct: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPAR--IVNISSPVTVNEGGNVNLLCLA 156
Query: 151 SGSKPAADIRW------FKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVI 204
G +P + W F ++ EI ++ ++ A
Sbjct: 157 VG-RPEPTVTWRQLRDGFTSEGEILEISDIQRGQAGEYEC-------------------- 195
Query: 205 CRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWT 264
V H +N+ P ++ ++Y P++ + S G+ +L CE+ P P W
Sbjct: 196 --VTHNGVNSAPDSRRVLVTVNYPPTITDVTSAR-TALGRAALLRCEAMAVP-PADFQWY 251
Query: 265 KDGGELPDPDRMVVSG-----------RELNILFLNKTDN--GTYRCEATNTIGQSSAEY 311
KD DR++ SG +LF N + G Y C A N +G SSA
Sbjct: 252 KD-------DRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASM 304
Query: 312 VLI 314
L+
Sbjct: 305 RLL 307
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 82.4 bits (202), Expect = 7e-16
Identities = 74/282 (26%), Positives = 116/282 (41%), Gaps = 26/282 (9%)
Query: 33 NVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSIS 92
++ V+ G +A C V + WS D K +R + + +
Sbjct: 6279 SIDVIAGESADFECHVTGAQPMRITWSK---------DNKEIRPGGNYTITCVGNTPHLR 6329
Query: 93 VSDVSLSDEGQYTCSLFTMPVKTS-KAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTS 151
+ V D GQYTC K A L+V P+ + S +G+ +QL CK S
Sbjct: 6330 ILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKIS 6389
Query: 152 GSKPAADIRWFKNDKEIKDV-KYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHE 210
GS P + WF+ND E+ + KY N + L ++D IC +
Sbjct: 6390 GS-PEIKVSWFRNDSELHESWKY------NMSFINSVALLTINEASAEDSGDYICEAHNG 6442
Query: 211 SLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGEL 270
+A+ A L + P PS +G +IL CE G P P V+W KD ++
Sbjct: 6443 VGDASCSTA---LTVKAPPVFTQKPSPVGALKGSDVILQCEISGTP-PFEVVWVKDRKQV 6498
Query: 271 PDPDRMVVSGRE----LNILFLNKTDNGTYRCEATNTIGQSS 308
+ + ++ + L+IL L +D G Y C+ATN +G +
Sbjct: 6499 RNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDT 6540
Score = 73.6 bits (179), Expect = 3e-13
Identities = 77/309 (24%), Positives = 132/309 (42%), Gaps = 25/309 (8%)
Query: 54 TSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVSLSDEGQYTCSLFT-MP 112
T+++ + P + D + +R++ + S + ++ S V ++ G+YTC +
Sbjct: 7513 TTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAG 7572
Query: 113 VKTSKAYLTVLG---VPEKPQISGFSSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIK 169
++ A L+VL + EKP+ S V GD L C +G+ P +WFK+ KE+
Sbjct: 7573 MQECFATLSVLEPATIVEKPE----SIKVTTGDTCTLECTVAGT-PELSTKWFKDGKELT 7627
Query: 170 DVKYLKEEDANRKTFTVSSTLDFRVDRSDDGV---AVICRVDHESLNATPQVAMQVLEIH 226
K N+ VS V SD GV V V +S A+ QV+ + +
Sbjct: 7628 SDNKYKISFFNK----VSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPS 7683
Query: 227 YTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGRE---- 282
+T +K G +++ C+ G P P V W +G E+ + + +
Sbjct: 7684 FTRKLKETNGL----SGSSVVMECKVYGSP-PISVSWFHEGNEISSGRKYQTTLTDNTCA 7738
Query: 283 LNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLLPTTIIPSLTTATVTTTVAI 342
L + L ++D+G Y C ATN G L V + P+ + + LT VT T +
Sbjct: 7739 LTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIV 7798
Query: 343 TTSPTTSAT 351
+P S +
Sbjct: 7799 KGTPPFSVS 7807
Score = 67.8 bits (164), Expect = 2e-11
Identities = 74/315 (23%), Positives = 127/315 (40%), Gaps = 28/315 (8%)
Query: 44 LTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVSLSDEGQ 103
L C+VD++ ++ WS Q+ D K +++I ++ + L D G
Sbjct: 3663 LECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKI---------ATLEIPLAKLKDSGT 3713
Query: 104 YTCSLFTMPVKTS-KAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGSKPAADIRWF 162
Y C+ +S A +TV P + S ++ G+ +L CK GS P + WF
Sbjct: 3714 YVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGS-PVIQVTWF 3772
Query: 163 KNDKEIKDVKYLKEEDANRKTFTVS-STLDFRVDRSDDGVAVICRVDHESLNATPQVAMQ 221
KN+KE L E + R F S + LD + +D + C ++ + + +
Sbjct: 3773 KNNKE------LSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIV 3826
Query: 222 VLEIHYTPS-VKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSG 280
+ E PS +K + + G +L CE G P + W KD ++ + +
Sbjct: 3827 IKE---PPSFIKTLEPADIVR-GTNALLQCEVSGTG-PFEISWFKDKKQIRSSKKYRLFS 3881
Query: 281 RE----LNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLLPTTIIPSLTTATV 336
++ L I N D G Y C N +G+ ++ + P + + +L TV
Sbjct: 3882 QKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQTV 3941
Query: 337 TTTVAITTSPTTSAT 351
T A+ S S T
Sbjct: 3942 TLQAAVRGSEPISVT 3956
Score = 67.4 bits (163), Expect = 2e-11
Identities = 72/291 (24%), Positives = 120/291 (41%), Gaps = 38/291 (13%)
Query: 29 PLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHE 88
P++ ++ + E GT C V + W+ D + +R + +
Sbjct: 7218 PVSVDLALGESGT--FKCHVTGTAPIKITWAK---------DNREIRPGGNYKMTLVENT 7266
Query: 89 LSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSP---VMEGDLMQ 145
+++V V D GQYTC + K S + LGV E P+ P V + + +
Sbjct: 7267 ATLTVLKVGKGDAGQYTCYASNIAGKDSCS--AQLGVQEPPRFIKKLEPSRIVKQDEFTR 7324
Query: 146 LTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVS-STLDFRVDRSDDGVAVI 204
CK GS P + W+K++ EI+ E R +F S + L+ +D
Sbjct: 7325 YECKIGGS-PEIKVLWYKDETEIQ------ESSKFRMSFVDSVAVLEMHNLSVEDSGDYT 7377
Query: 205 CRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQE---GQPLILTCESKGKPLPEPV 261
C + + +A+ +++V E I P P E G + L CE +G P P V
Sbjct: 7378 CEAHNAAGSASSSTSLKVKE------PPIFRKKPHPIETLKGADVHLECELQGTP-PFHV 7430
Query: 262 LWTKDGGELPDPDRMVVSGRE----LNILFLNKTDNGTYRCEATNTIGQSS 308
W KD EL + + ++IL ++ D G Y+C+ATN +G +
Sbjct: 7431 SWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDT 7481
Score = 67.0 bits (162), Expect = 3e-11
Identities = 67/265 (25%), Positives = 117/265 (44%), Gaps = 21/265 (7%)
Query: 61 PAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYL 120
P + +++ DK+ LR ++ + + SI + +V SD G+Y C S +
Sbjct: 5544 PPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCK--AQNEVGSDTCV 5601
Query: 121 TVLGVPEKPQ-ISGFSS-PVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEED 178
+ + E P+ +S +S V+ G+ +L G++P ++W K +E+ ++E +
Sbjct: 5602 CTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIF-VQWLKEKEEV-----IRESE 5655
Query: 179 ANRKTFTVS-STLDFRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPST 237
R TF + +TL F + IC++ ++ + VLE P+V + +
Sbjct: 5656 NIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLE----PAVIVEKAG 5711
Query: 238 PFP-QEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSG----RELNILFLNKTD 292
P G+ L C+ G P V W KDG L + S L IL + + D
Sbjct: 5712 PMTVTVGETCTLECKVAGTP-ELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQD 5770
Query: 293 NGTYRCEATNTIGQSSAEYVLIVHD 317
GTY + N +G+SS V+ V D
Sbjct: 5771 AGTYTFQVQNNVGKSSCTAVVDVSD 5795
Score = 65.9 bits (159), Expect = 7e-11
Identities = 63/237 (26%), Positives = 99/237 (41%), Gaps = 17/237 (7%)
Query: 91 ISVSDVSLSDEGQYTCSLFTMPVKTS-KAYLTVLGVPEKPQISGFSSPVME--GDLMQLT 147
+ + ++ D GQY C + K S A + +L E P PV GD L
Sbjct: 7925 LEIPSSTVEDAGQYNCYIENASGKDSCSAQILIL---EPPYFVKQLEPVKVSVGDSASLQ 7981
Query: 148 CKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRV 207
C+ +G+ P + W+K D +++ K N V++ + +VD +D G IC+
Sbjct: 7982 CQLAGT-PEIGVSWYKGDTKLRPTTTYKMHFRNN----VATLVFNQVDINDSG-EYICKA 8035
Query: 208 DHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDG 267
++ + + V E PS G P++ C G P V W KDG
Sbjct: 8036 ENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSE-PISVSWYKDG 8094
Query: 268 GELPDPDRMVVSGRE----LNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPN 320
L D + S + LNI +++ G Y C ATN IG +S+ LI+ + N
Sbjct: 8095 KPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKN 8151
Score = 64.7 bits (156), Expect = 2e-10
Identities = 80/329 (24%), Positives = 135/329 (41%), Gaps = 42/329 (12%)
Query: 37 VEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELS--ISVS 94
++G L C V + S+QW + DD++ + E + S+H+ + + +S
Sbjct: 4687 IKGSFIDLECIVAGSHPISIQW--------FKDDQEI---SASEKYKFSFHDNTAFLEIS 4735
Query: 95 DVSLSDEGQYTCSLFTMPVKTS-KAYLTVLGVP---EKPQISGFSSPVMEGDLMQLTCKT 150
+ +D G YTCS +LTV P EKPQ S V +QL
Sbjct: 4736 QLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQ----SQDVNPNTRVQLKALV 4791
Query: 151 SGSKPAADIRWFKNDKEIKD--VKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVD 208
G+ P I+WFK++KE+ + + ++D S++L+ ++ D IC++
Sbjct: 4792 GGTAPMT-IKWFKDNKELHSGAARSVWKDDT-------STSLELFAAKATDSGTYICQLS 4843
Query: 209 HESLNATPQVAMQVLEIHYTPSVKIIPSTPFP--QEGQPLILTCESKGKPLPEPVLWTKD 266
++ AT + + V E P I +P + GQ C+ G P V W D
Sbjct: 4844 NDVGTATSKATLFVKE----PPQFIKKPSPVLVLRNGQSTTFECQITGTPKIR-VSWYLD 4898
Query: 267 GGELPDPDRMVVSGRE----LNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTL 322
G E+ + +S + I ++GTY CEA N G +S L V + P +
Sbjct: 4899 GNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFI 4958
Query: 323 LPTTIIPSLTTATVTTTVAITTSPTTSAT 351
+ + + V +T +P T
Sbjct: 4959 RELKPVEVVKYSDVELECEVTGTPPFEVT 4987
Score = 63.2 bits (152), Expect = 5e-10
Identities = 63/237 (26%), Positives = 103/237 (43%), Gaps = 21/237 (8%)
Query: 91 ISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISG---FSSPVMEGDLMQLT 147
+++ V S GQYTC + T V S + T+L V E P+ S V GD +L
Sbjct: 5387 LNLYSVDASKTGQYTCHV-TNDVG-SDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLE 5444
Query: 148 CKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVS-STLDFRVDRSDDGVAVICR 206
CK +GS P + WF+N+ E L D R TF S + + ++D IC
Sbjct: 5445 CKIAGS-PEIRVVWFRNEHE------LPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICE 5497
Query: 207 VDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKD 266
+ + + + + V E P P + + L CE G P P V+W KD
Sbjct: 5498 AQNPAGSTSCSTKVIVKE---PPVFSSFPPIVETLKNAEVSLECELSGTP-PFEVVWYKD 5553
Query: 267 GGELPDPDRMVVSGRE----LNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
+L + ++ + ++IL ++ +D G Y C+A N +G + + + + P
Sbjct: 5554 KRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPP 5610
Score = 62.4 bits (150), Expect = 8e-10
Identities = 70/295 (23%), Positives = 120/295 (40%), Gaps = 28/295 (9%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSI 91
+NV V GT L C++ S P + + + D K+ +R + S+
Sbjct: 4120 RNVDSVVNGTCRLDCKI--------AGSLPMRVSWFKDGKEIAASDRYRIAFVEG-TASL 4170
Query: 92 SVSDVSLSDEGQYTC-SLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKT 150
+ V ++D G +TC + ++ K S L V P G S V+ G + L
Sbjct: 4171 EIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPG-SKDVLPGSAVCLKSTF 4229
Query: 151 SGSKPAADIRWFKNDKEIKDVK--YLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVD 208
GS P IRWFK +KE+ Y+ +E + S+L+ + ++ D C+V
Sbjct: 4230 QGSTPLT-IRWFKGNKELVSGGSCYITKE-------ALESSLELYLVKTSDSGTYTCKVS 4281
Query: 209 HESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGG 268
+ + + V E V+ + + ++G L C+ G P P + W +
Sbjct: 4282 NVAGGVECSANLFVKEP--ATFVEKLEPSQLLKKGDATQLACKVTGTP-PIKITWFANDR 4338
Query: 269 ELPDPDR----MVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
E+ + + V S L + + D+G Y CEA N G ++IV + P
Sbjct: 4339 EIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESP 4393
Score = 61.6 bits (148), Expect = 1e-09
Identities = 80/351 (22%), Positives = 144/351 (41%), Gaps = 38/351 (10%)
Query: 12 VPAAASKNKVKGSQGQFPLT-----QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTL 66
+ A+SK + + Q P + +++ G LTCR++ + + W
Sbjct: 6157 IGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCW-------- 6208
Query: 67 YFDDKKALRDNRIELVRASWHELSISVSDVSLSDEGQYTCSLFT-MPVKTSKAYLTVLGV 125
+ D LRD+ + ++ + LS GQY+CS + +S A LT
Sbjct: 6209 -YRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREP 6267
Query: 126 PEKP--QISGFSSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKT 183
+ P I S V+ G+ C +G++P I W K++KEI+ N
Sbjct: 6268 KKSPFFDIKPVSIDVIAGESADFECHVTGAQPMR-ITWSKDNKEIRP-------GGNYTI 6319
Query: 184 FTVSSTLDFR---VDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPS-VKIIPSTPF 239
V +T R V + D G C+ ++ + L + P VK + ++
Sbjct: 6320 TCVGNTPHLRILKVGKGDSG-QYTCQATND---VGKDMCSAQLSVKEPPKFVKKLEASKV 6375
Query: 240 PQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSG-RELNILFLNKT---DNGT 295
++G+ + L C+ G P + V W ++ EL + + +S + +L +N+ D+G
Sbjct: 6376 AKQGESIQLECKISGSPEIK-VSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGD 6434
Query: 296 YRCEATNTIGQSSAEYVLIVHDVPNTLLPTTIIPSLTTATVTTTVAITTSP 346
Y CEA N +G +S L V P + + +L + V I+ +P
Sbjct: 6435 YICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTP 6485
Score = 61.6 bits (148), Expect = 1e-09
Identities = 72/323 (22%), Positives = 129/323 (39%), Gaps = 34/323 (10%)
Query: 34 VTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISV 93
V V G +A C V + W+ D + +R + + ++V
Sbjct: 8162 VDAVVGESADFECHVTGTQPIKVSWAK---------DSREIRSGGKYQISYLENSAHLTV 8212
Query: 94 SDVSLSDEGQYTCSLFTMPVKTS-KAYLTVLGVPEKPQISGFSSPVME---GDLMQLTCK 149
V D GQYTC K S A L + P + S +E G+ +L +
Sbjct: 8213 LKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGR 8272
Query: 150 TSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRS--DDGVAVICRV 207
+GS+P + W+KN+ EI+ +N + ++TL +V ++ +D C+V
Sbjct: 8273 VAGSQPIT-VAWYKNNIEIQPT-------SNCEITFKNNTLVLQVRKAGMNDAGLYTCKV 8324
Query: 208 DHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDG 267
+++ +A ++ + E P + EG+ + L+C +G P + W K G
Sbjct: 8325 SNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSE-PIRIQWLKAG 8383
Query: 268 GELPDPDRMVVSGRE----LNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLL 323
E+ DR S L + + K D+G Y C+A+N G + + + + D P
Sbjct: 8384 REIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKP---- 8439
Query: 324 PTTIIPSLTTATVTTTVAITTSP 346
+ P+ A V + + P
Sbjct: 8440 --AVAPATKKAAVDGRLFFVSEP 8460
Score = 60.1 bits (144), Expect = 4e-09
Identities = 64/282 (22%), Positives = 124/282 (43%), Gaps = 30/282 (10%)
Query: 61 PAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVSLSDEGQYTCSLFT-MPVKTSKAY 119
P +T++ D AL + + + ++ + +S++++ D G Y+C +A
Sbjct: 3578 PVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAE 3637
Query: 120 LTVLGVPEKPQISGFSSPVMEG--DLMQLTCKTSGSKPAADIRWFKNDKEI---KDVKYL 174
L ++ +KP PV + L C+ + + W K+ +++ KD K
Sbjct: 3638 LIII---DKPHFIKELEPVQSAINKKVHLECQVDEDRKVT-VTWSKDGQKLPPGKDYKIC 3693
Query: 175 KEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPS-VKI 233
E+ +TL+ + + D +C +E+ +++ + V E PS VK
Sbjct: 3694 FEDKI--------ATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVRE---PPSFVKK 3742
Query: 234 IPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRM----VVSGRELNILFLN 289
+ + G+ L C+ KG P+ + V W K+ EL + + + V S L+I +
Sbjct: 3743 VDPSYLMLPGESARLHCKLKGSPVIQ-VTWFKNNKELSESNTVRMYFVNSEAILDITDVK 3801
Query: 290 KTDNGTYRCEATNTIGQSSAEYVLIVHDVPN---TLLPTTII 328
D+G+Y CEA N +G S +++ + P+ TL P I+
Sbjct: 3802 VEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIV 3843
Score = 59.7 bits (143), Expect = 5e-09
Identities = 73/314 (23%), Positives = 123/314 (39%), Gaps = 30/314 (9%)
Query: 34 VTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISV 93
V V G +A L C++ + W Y D K LR + + ++
Sbjct: 7970 VKVSVGDSASLQCQLAGTPEIGVSW--------YKGDTK-LRPTTTYKMHFRNNVATLVF 8020
Query: 94 SDVSLSDEGQYTCSLFTMPVKTSKA-YLTVLGVPEKPQISGFSSPVME--GDLMQLTCKT 150
+ V ++D G+Y C + S + +LTV P S V E G + C
Sbjct: 8021 NQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAI 8080
Query: 151 SGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVA--VICRVD 208
SGS+P + + W+K+ K +KD N +T + +T + ++D +A C
Sbjct: 8081 SGSEPIS-VSWYKDGKPLKD-------SPNVQTSFLDNTATLNIFKTDRSLAGQYSCTAT 8132
Query: 209 HESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGG 268
+ +A+ + + E P I + G+ C G P V W KD
Sbjct: 8133 NPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQ-PIKVSWAKDSR 8191
Query: 269 ELPDPDRMVVSGRE----LNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLLP 324
E+ + +S E L +L ++K D+G Y C A N +G+ S L ++ L+P
Sbjct: 8192 EIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQL---NIKERLIP 8248
Query: 325 TTIIPSLTTATVTT 338
+ L+ T
Sbjct: 8249 PSFTKRLSETVEET 8262
Score = 59.3 bits (142), Expect = 7e-09
Identities = 81/325 (24%), Positives = 131/325 (40%), Gaps = 44/325 (13%)
Query: 49 DQNDNTSLQWS----NPAQQTL-YFDDKKALRDNRIELVRASWHELSISVSDVSLSDEGQ 103
D N NT +Q A T+ +F D K L V S+ + +D G
Sbjct: 4778 DVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGT 4837
Query: 104 YTCSLFT-MPVKTSKAYLTVLGVPEKPQISGFSSPVM---EGDLMQLTCKTSGSKPAADI 159
Y C L + TSKA L V E PQ SPV+ G C+ +G+ P +
Sbjct: 4838 YICQLSNDVGTATSKA---TLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGT-PKIRV 4893
Query: 160 RWFKNDKEIKDV-KYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQV 218
W+ + EI + K+ TF +S R ++ +C +++ A+ +
Sbjct: 4894 SWYLDGNEITAIQKHGISFIDGLATFQISGA------RVENSGTYVCEARNDAGTASCSI 4947
Query: 219 AMQVLE----IHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPD 274
++V E I V+++ + E CE G P P V W K+ E+
Sbjct: 4948 ELKVKEPPTFIRELKPVEVVKYSDVELE-------CEVTGTP-PFEVTWLKNNREIRSSK 4999
Query: 275 RMVVSGR----ELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLL----PTT 326
+ ++ R L+I + +D G Y+C +N G S + + + P+ + TT
Sbjct: 5000 KYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTT 5059
Query: 327 IIPSLTTATVTTTVAITTSPTTSAT 351
++ S +AT +TVA SP S T
Sbjct: 5060 VLKS--SATFQSTVA--GSPPISIT 5080
Score = 58.9 bits (141), Expect = 9e-09
Identities = 71/286 (24%), Positives = 112/286 (39%), Gaps = 49/286 (17%)
Query: 88 ELSISVSDVSLSDEGQYTCSLFTMPVKTS-KAYLTVLGVPEKPQISGFSSPVMEGDLMQL 146
E S+ + V SD G YTC + + A L V + S + +GD QL
Sbjct: 4260 ESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQL 4319
Query: 147 TCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRS-DDGVAVIC 205
CK +G+ P I WF ND+EIK E +R +F S+ + D +D +C
Sbjct: 4320 ACKVTGTPPIK-ITWFANDREIK------ESSKHRMSFVESTAVLRLTDVGIEDSGEYMC 4372
Query: 206 RVDHESLNATPQVAMQVLEIHYTPSVKIIPSTP-FPQEGQPL--------ILTCESKGKP 256
+E+ + + S+ I+ +P F +E +P+ +L E G P
Sbjct: 4373 EAQNEAGS------------DHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEVAGTP 4420
Query: 257 LPEPVLWTKDGGELPDPDRMVVSGRE-----------LNILFLNKTDNGTYRCEATNTIG 305
P + W KD + ++ SGR+ L IL D G Y+C TN +G
Sbjct: 4421 -PFEITWFKD-------NTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVG 4472
Query: 306 QSSAEYVLIVHDVPNTLLPTTIIPSLTTATVTTTVAITTSPTTSAT 351
S + + + P+ + SL T + S + T
Sbjct: 4473 SSICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVT 4518
Score = 58.5 bits (140), Expect = 1e-08
Identities = 67/297 (22%), Positives = 115/297 (38%), Gaps = 27/297 (9%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSI 91
++V V G A L C+VD + W + + LR ++ + S+
Sbjct: 7027 EHVEAVIGEPATLQCKVDGTPEIRISW---------YKEHTKLRSAPAYKMQFKNNVASL 7077
Query: 92 SVSDVSLSDEGQYTCSLF-TMPVKTSKAYLTVLGVPEKPQISGFSSPVME--GDLMQLTC 148
++ V SD G+Y+C ++ S A L + P + V E G + C
Sbjct: 7078 VINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETLGFPVAFEC 7137
Query: 149 KTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVA--VICR 206
+ +GS+P + W+K+ +KD DAN +T V + ++ ++D C
Sbjct: 7138 RINGSEPL-QVSWYKDGVLLKD-------DANLQTSFVHNVATLQILQTDQSHIGQYNCS 7189
Query: 207 VDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKD 266
+ A+ + + E P + P + G+ C G P + W KD
Sbjct: 7190 ASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTA-PIKITWAKD 7248
Query: 267 GGELPDPDR----MVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
E+ +V + L +L + K D G Y C A+N G+ S L V + P
Sbjct: 7249 NREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPP 7305
Score = 57.8 bits (138), Expect = 2e-08
Identities = 68/295 (23%), Positives = 109/295 (36%), Gaps = 26/295 (8%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSI 91
++V V E L C V ++W D K + +R + + S
Sbjct: 5148 KSVDVTEKDPMTLECVVAGTPELKVKW---------LKDGKQIVPSRYFSMSFENNVASF 5198
Query: 92 SVSDVSLSDEGQYTCSLFT-MPVKTSKAYLTVLGVPEKPQISGFSSPVME--GDLMQLTC 148
+ V D GQYT + + AYL VL P + + + + G + + C
Sbjct: 5199 RIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMEC 5258
Query: 149 KTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVD 208
K SGS P + +WFK+ KEI + R + L+ +D C+V
Sbjct: 5259 KVSGSLPIS-AQWFKDGKEISTSAKYRLVCHERSVSLEVNNLEL-----EDTANYTCKVS 5312
Query: 209 HESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGG 268
+ A +L + PS + P + KG P P + W KD
Sbjct: 5313 NV---AGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTP-PFKIKWFKDDV 5368
Query: 269 ELPDPDRMVV----SGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
EL + + S LN+ ++ + G Y C TN +G S +L+V + P
Sbjct: 5369 ELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPP 5423
Score = 56.6 bits (135), Expect = 4e-08
Identities = 55/236 (23%), Positives = 99/236 (41%), Gaps = 24/236 (10%)
Query: 96 VSLSDEGQYTCSLF-TMPVKTSKAYLTVLGVPEKPQISGFSSPVME-----GDLMQLTCK 149
V+++D G+YTC ++ +SK TV + E+ F+ + + G + LTC+
Sbjct: 6141 VNINDSGEYTCKAENSIGTASSK---TVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCR 6197
Query: 150 TSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSD--DGVAVICRV 207
+GS P + W+++ ++D D N +T V + ++ ++D C
Sbjct: 6198 LNGSAPI-QVCWYRDGVLLRD-------DENLQTSFVDNVATLKILQTDLSHSGQYSCSA 6249
Query: 208 DHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDG 267
+ A+ + E +P I P + G+ C G P + W+KD
Sbjct: 6250 SNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQ-PMRITWSKDN 6308
Query: 268 GELPDPDRMVVS----GRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
E+ ++ L IL + K D+G Y C+ATN +G+ L V + P
Sbjct: 6309 KEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPP 6364
Score = 55.8 bits (133), Expect = 7e-08
Identities = 66/296 (22%), Positives = 121/296 (40%), Gaps = 36/296 (12%)
Query: 29 PLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHE 88
P +QN+ EG + TC + + ++W F + + + + S +
Sbjct: 33140 PRSQNIN--EGQNVLFTCEISGEPSPEIEW---------FKNNLPISISSNVSISRSRNV 33188
Query: 89 LSISVSDVSLSDEGQYTCSLFTMPVKTSK-AYLTVLGVPEKP------QISGFSSPVMEG 141
S+ + + S+SD G+YT + S A L VL + E+P + SG +S ++G
Sbjct: 33189 YSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTS--LQG 33246
Query: 142 DLMQLTCKTSGSKPAADIRWFKNDK--EIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDD 199
+ + S SK A F + + ++K+ A+ ++SS + V+ S
Sbjct: 33247 SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKF-----ASMSAQSMSSMQESFVEMSSS 33301
Query: 200 GVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPE 259
I + + + + + I P ++ +PS EG+ L + C G+P PE
Sbjct: 33302 SFMGISNMTQLESSTSKMLKAGIRGI--PPKIEALPSDISIDEGKVLTVACAFTGEPTPE 33359
Query: 260 PVLWTKDGGEL--PDPDRMVVSGRE----LNILFLNKTDNGTYRCEATNTIGQSSA 309
V W+ G ++ + R + + L I+ + K D G Y N G SA
Sbjct: 33360 -VTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSA 33414
Score = 55.5 bits (132), Expect = 1e-07
Identities = 65/322 (20%), Positives = 122/322 (37%), Gaps = 27/322 (8%)
Query: 33 NVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSIS 92
++ V +G A L + + +W Q+ K + + +++
Sbjct: 4587 SIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILK--------- 4637
Query: 93 VSDVSLSDEGQYTCSLFTMPVKTS-KAYLTVLGVPEKPQISGFSSPV--MEGDLMQLTCK 149
+ D G+YT + ++S KA + VL + P + + ++G + L C
Sbjct: 4638 IISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECI 4697
Query: 150 TSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDH 209
+GS P + I+WFK+D+EI + K + F S L+ D + + H
Sbjct: 4698 VAGSHPIS-IQWFKDDQEISASEKYKFSFHDNTAFLEISQLE-GTDSGTYTCSATNKAGH 4755
Query: 210 ESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGE 269
+ V + S + P+T + G P + W KD E
Sbjct: 4756 NQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALV--------GGTAPMTIKWFKDNKE 4807
Query: 270 LPDPDRMVV----SGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTL-LP 324
L V + L + TD+GTY C+ +N +G ++++ L V + P + P
Sbjct: 4808 LHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKP 4867
Query: 325 TTIIPSLTTATVTTTVAITTSP 346
+ ++ + T IT +P
Sbjct: 4868 SPVLVLRNGQSTTFECQITGTP 4889
Score = 54.7 bits (130), Expect = 2e-07
Identities = 76/323 (23%), Positives = 128/323 (39%), Gaps = 40/323 (12%)
Query: 37 VEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSIS--VS 94
V G + + C+V + S QW + D K+ + LV HE S+S V+
Sbjct: 5249 VLGSSIHMECKVSGSLPISAQW--------FKDGKEISTSAKYRLV---CHERSVSLEVN 5297
Query: 95 DVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQ--ISGFSSPVMEGDLMQLTCKTSG 152
++ L D YTC + V A +L V E P + + ++ G
Sbjct: 5298 NLELEDTANYTCKVSN--VAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKG 5355
Query: 153 SKPAADIRWFKNDKEIKDVKYLKEEDANRKTF-----TVSSTLDFRVDRSDDGVAVICRV 207
+ P I+WFK+D E+ + K F + S + VD S G C V
Sbjct: 5356 TPPFK-IKWFKDDVELV---------SGPKCFIGLEGSTSFLNLYSVDASKTG-QYTCHV 5404
Query: 208 DHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDG 267
++ + +L VK + ++ + G L C+ G P V+W ++
Sbjct: 5405 TNDV--GSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIR-VVWFRNE 5461
Query: 268 GELPDPDR----MVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLL 323
ELP D+ + S + + L+ D+G + CEA N G +S +IV + P
Sbjct: 5462 HELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSS 5521
Query: 324 PTTIIPSLTTATVTTTVAITTSP 346
I+ +L A V+ ++ +P
Sbjct: 5522 FPPIVETLKNAEVSLECELSGTP 5544
Score = 54.7 bits (130), Expect = 2e-07
Identities = 61/271 (22%), Positives = 108/271 (39%), Gaps = 31/271 (11%)
Query: 90 SISVSDVSLSDEGQYTCSLFT-MPVKTSKAYLTVLG---VPEKPQISGFSSPVMEGDLMQ 145
++ + S+ G+Y C + ++ A LTVL + EKP+ V G+
Sbjct: 6608 TLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPE----PMTVTTGNPFA 6663
Query: 146 LTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRV---DRSDDGV- 201
L C +G+ P +WFK+ +E+ D+ ++ ++ + SD G+
Sbjct: 6664 LECVVTGT-PELSAKWFKDGRELS-------ADSKHHITFINKVASLKIPCAEMSDKGLY 6715
Query: 202 --AVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPE 259
V V + + V+ +++ + +K + + G ++L C G P
Sbjct: 6716 SFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAIL----GASVVLECRVSGSA-PI 6770
Query: 260 PVLWTKDGGELPDPDRMVVSGRE----LNILFLNKTDNGTYRCEATNTIGQSSAEYVLIV 315
V W +DG E+ + S E LN+ L +D G Y C A N G VL V
Sbjct: 6771 SVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTV 6830
Query: 316 HDVPNTLLPTTIIPSLTTATVTTTVAITTSP 346
+ P+ + L ++T T I +P
Sbjct: 6831 QEPPSFEQTPDSVEVLPGMSLTFTSVIRGTP 6861
Score = 52.0 bits (123), Expect = 1e-06
Identities = 79/331 (23%), Positives = 122/331 (36%), Gaps = 44/331 (13%)
Query: 34 VTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISV 93
+TV G T L C+V S++W + K N+I S+ +
Sbjct: 5713 MTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKIS---------SLRI 5763
Query: 94 SDVSLSDEGQYTCSLFTMPVKTSKAYLT-VLGVPEKPQISGFSSPVME-----GDLMQLT 147
V D G YT F + K+ T V+ V ++ F+ + G L
Sbjct: 5764 LSVERQDAGTYT---FQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILE 5820
Query: 148 CKTSGSKPAADIRWF-KNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDG--VAVI 204
CK +GS P + + WF + K + KY N T ++S +D SD G V
Sbjct: 5821 CKVAGSSPIS-VAWFHEKTKIVSGAKYQTTFSDNVCTLQLNS-----LDSSDMGNYTCVA 5874
Query: 205 CRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWT 264
V A VL + PS P G+ + T +G P P V W
Sbjct: 5875 ANV------AGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTP-PFKVNWF 5927
Query: 265 KDGGELPDPDRMVV----SGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPN 320
+ EL DR + + EL + ++ + +G Y C +N GQ+S L V +
Sbjct: 5928 RGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKE--- 5984
Query: 321 TLLPTTIIPSLTTATVTTTVAITTSPTTSAT 351
P + L+ +V +I T + T
Sbjct: 5985 ---PAAFLKRLSDHSVEPGKSIILESTYTGT 6012
Score = 52.0 bits (123), Expect = 1e-06
Identities = 76/323 (23%), Positives = 124/323 (38%), Gaps = 31/323 (9%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSI 91
++V + G + +L CRV + S+ W F D + S + ++
Sbjct: 6748 KDVNAILGASVVLECRVSGSAPISVGW---------FQDGNEIVSGPKCQSSFSENVCTL 6798
Query: 92 SVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGF--SSPVMEGDLMQLTCK 149
++S + SD G YTC V S VL V E P S V+ G + T
Sbjct: 6799 NLSLLEPSDTGIYTC--VAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSV 6856
Query: 150 TSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLD-FRVDRSDDGVAVICRVD 208
G+ P ++WFK +E+ + E N + L+ F V + G C V
Sbjct: 6857 IRGTPPFK-VKWFKGSREL-----VPGESCNISLEDFVTELELFEVQPLESG-DYSCLVT 6909
Query: 209 HESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQE-GQPLILTCESKGKPLPEPVLWTKDG 267
+++ +A+ + V E P+ + F E G P++L G P P V W KD
Sbjct: 6910 NDAGSASCTTHLFVKE----PATFVKRLADFSVETGSPIVLEATYTGTP-PISVSWIKDE 6964
Query: 268 GELPDPDRMVVSGRE----LNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLL 323
+ +R ++ E L IL D Y C N GQ E ++ V + P +
Sbjct: 6965 YLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIE 7024
Query: 324 PTTIIPSLTTATVTTTVAITTSP 346
P + ++ T + +P
Sbjct: 7025 PLEHVEAVIGEPATLQCKVDGTP 7047
Score = 52.0 bits (123), Expect = 1e-06
Identities = 73/316 (23%), Positives = 131/316 (41%), Gaps = 52/316 (16%)
Query: 30 LTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHEL 89
L++ V EG + L RV + ++ W Y ++ + + E+ + + L
Sbjct: 8255 LSETVEETEGNSFKLEGRVAGSQPITVAW--------YKNNIEIQPTSNCEITFKN-NTL 8305
Query: 90 SISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQI-SGFSSPVM--EGDLMQL 146
+ V ++D G YTC + V+ P+KP + +PV EG+ +QL
Sbjct: 8306 VLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQL 8365
Query: 147 TCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSS---TLDFRVDRSDDGVAV 203
+C GS+P I+W K +EIK ++R +F+ +S L+ R D
Sbjct: 8366 SCHVQGSEPIR-IQWLKAGREIKP--------SDRCSFSFASGTAVLELRDVAKADSGDY 8416
Query: 204 ICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTP---------FPQEGQPLILTCESK- 253
+C+ + + + T + + + + + P+T F E Q + + ++
Sbjct: 8417 VCKASNVAGSDTTKSKVTIKD-----KPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTA 8471
Query: 254 -------GKPLPEPVLWTKDGG-ELPDPDRMVVSGR----ELNILFLNKTDNGTYRCEAT 301
G P+P V WTK +L R+ + + +L I KTD+G YRC A
Sbjct: 8472 TFIAKVGGDPIPN-VKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAF 8530
Query: 302 NTIGQSSAEYVLIVHD 317
N G+ + L V +
Sbjct: 8531 NEHGEIESNVNLQVDE 8546
Score = 51.6 bits (122), Expect = 1e-06
Identities = 73/284 (25%), Positives = 110/284 (38%), Gaps = 33/284 (11%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSI 91
+N V G + IL C+V + S+ W F +K + S + ++
Sbjct: 5807 KNTGGVLGASCILECKVAGSSPISVAW---------FHEKTKIVSGAKYQTTFSDNVCTL 5857
Query: 92 SVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSP--VMEGDLMQLTCK 149
++ + SD G YTC V S VL V E P P V+ G + T
Sbjct: 5858 QLNSLDSSDMGNYTC--VAANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSV 5915
Query: 150 TSGSKPAADIRWFKNDKEIK--DVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRV 207
G+ P + WF+ +E+ D + ED TV+ F +D S G C V
Sbjct: 5916 IRGTPPFK-VNWFRGARELVKGDRCNIYFED------TVAELELFNIDISQSG-EYTCVV 5967
Query: 208 DHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQE-GQPLILTCESKGKPLPEPVLWTKD 266
+ + A+ + V E P+ + + E G+ +IL G LP V W KD
Sbjct: 5968 SNNAGQASCTTRLFVKE----PAAFLKRLSDHSVEPGKSIILESTYTGT-LPISVTWKKD 6022
Query: 267 GGELPDPDRMVVSGRE----LNILFLNKTDNGTYRCEATNTIGQ 306
G + ++ + E L IL K D G Y CE N G+
Sbjct: 6023 GFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGR 6066
Score = 51.2 bits (121), Expect = 2e-06
Identities = 70/306 (22%), Positives = 118/306 (38%), Gaps = 55/306 (17%)
Query: 36 VVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISVSD 95
V G A TC + N QW ++ +Y DK ++R ++ + S+ +
Sbjct: 3467 VALGHLAKFTCEIQSAPNVRFQWFKAGRE-IYESDKCSIRSSK--------YISSLEILR 3517
Query: 96 VSLSDEGQYTCSLFTMPVKTSKAYLTV-----LGVPEKPQISGFSSP----VMEGDLMQL 146
+ D G+YTC K S Y +V L V E + S P G +
Sbjct: 3518 TQVVDCGEYTC-------KASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKF 3570
Query: 147 TCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICR 206
C +G+ P + W K+ + + DA K S L + D GV C+
Sbjct: 3571 ICTVTGT-PVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQ----DRGV-YSCK 3624
Query: 207 VDHESLNATPQVAMQVLE-IHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTK 265
++ Q + +++ H+ ++ + S + + L C+ + V W+K
Sbjct: 3625 ASNKFGADICQAELIIIDKPHFIKELEPVQSA----INKKVHLECQ-VDEDRKVTVTWSK 3679
Query: 266 DGGELPDPDRMVVSGRELNILFLNK-----------TDNGTYRCEATNTIGQSSAEYVLI 314
DG +LP G++ I F +K D+GTY C A+N G SS +
Sbjct: 3680 DGQKLP-------PGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVT 3732
Query: 315 VHDVPN 320
V + P+
Sbjct: 3733 VREPPS 3738
Score = 51.2 bits (121), Expect = 2e-06
Identities = 71/289 (24%), Positives = 113/289 (39%), Gaps = 36/289 (12%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELS- 90
+++ V G T L C V S +W + D K+ DN+ ++ + ++++S
Sbjct: 7593 ESIKVTTGDTCTLECTVAGTPELSTKW--------FKDGKELTSDNKYKI--SFFNKVSG 7642
Query: 91 ISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTV-LGVPEKPQISGFSSPVME-----GDLM 144
+ + +V+ SD G Y+ F + K T L V ++ F+ + E G +
Sbjct: 7643 LKIINVAPSDSGVYS---FEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSV 7699
Query: 145 QLTCKTSGSKPAADIRWFKNDKEIKD-VKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAV 203
+ CK GS P + + WF EI KY N TV+ ++ SD G
Sbjct: 7700 VMECKVYGSPPIS-VSWFHEGNEISSGRKYQTTLTDNTCALTVN-----MLEESDSGDYT 7753
Query: 204 ICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLW 263
+ A L + PS P G + T KG P P V W
Sbjct: 7754 CIATN----MAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTP-PFSVSW 7808
Query: 264 TKDGGELPDPDRMVV----SGRELNILFLNKTDNGTYRCEATNTIGQSS 308
K EL DR V S EL + ++ + +G Y C +N G++S
Sbjct: 7809 FKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKAS 7857
Score = 50.8 bits (120), Expect = 2e-06
Identities = 75/328 (22%), Positives = 122/328 (37%), Gaps = 38/328 (11%)
Query: 34 VTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISV 93
+TV G L C V S +W F D + L + + S+ +
Sbjct: 6654 MTVTTGNPFALECVVTGTPELSAKW---------FKDGRELSADSKHHITFINKVASLKI 6704
Query: 94 SDVSLSDEGQYTCSLFTMPVKTSKAYLTV-LGVPEKPQISGFSSPVME-----GDLMQLT 147
+SD+G Y+ F + K+ TV + V ++ F + + G + L
Sbjct: 6705 PCAEMSDKGLYS---FEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLE 6761
Query: 148 CKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRV 207
C+ SGS P + + WF++ EI + + T++ +L ++ SD G+
Sbjct: 6762 CRVSGSAPIS-VGWFQDGNEIVSGPKC-QSSFSENVCTLNLSL---LEPSDTGIYTCVAA 6816
Query: 208 DHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDG 267
+ A VL + PS + P + G L T +G P P V W K
Sbjct: 6817 NV----AGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTP-PFKVKWFKGS 6871
Query: 268 GELPDPDRMVVSGR----ELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLL 323
EL + +S EL + + ++G Y C TN G +S L V +
Sbjct: 6872 RELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKE------ 6925
Query: 324 PTTIIPSLTTATVTTTVAITTSPTTSAT 351
P T + L +V T I T + T
Sbjct: 6926 PATFVKRLADFSVETGSPIVLEATYTGT 6953
Score = 50.4 bits (119), Expect = 3e-06
Identities = 66/263 (25%), Positives = 109/263 (41%), Gaps = 31/263 (11%)
Query: 71 KKALRDNRIELVRASWHE---LSISVSDVSLSDEGQYTCS-------LFTMPVKTSKAYL 120
+KALR I++ A E L S V +S+E + + + + KTS+A
Sbjct: 32974 QKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASE 33033
Query: 121 TVLGVPEKPQISGFSSP--VMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVK-YLKEE 177
V E I FS+ + EG + L +G A D++W N E+ + + Y
Sbjct: 33034 EVRTHAE---IKAFSTQMSINEGQRLVLKANIAG---ATDVKWVLNGVELTNSEEYRYGV 33087
Query: 178 DANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPST 237
+ +T T+ + D+G+ E + E+ P+ P +
Sbjct: 33088 SGSDQTLTIK-----QASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRS 33142
Query: 238 PFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGRELNILFL-----NKTD 292
EGQ ++ TCE G+P PE + W K+ + + +S R N+ L + +D
Sbjct: 33143 QNINEGQNVLFTCEISGEPSPE-IEWFKNNLPISISSNVSIS-RSRNVYSLEIRNASVSD 33200
Query: 293 NGTYRCEATNTIGQSSAEYVLIV 315
+G Y +A N GQ SA L+V
Sbjct: 33201 SGKYTIKAKNFRGQCSATASLMV 33223
Score = 50.1 bits (118), Expect = 4e-06
Identities = 71/322 (22%), Positives = 126/322 (39%), Gaps = 27/322 (8%)
Query: 33 NVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSIS 92
++TVV G A L ++ +QW ++ + + + +R +E V ++
Sbjct: 5618 SLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIR--ESENIRITFVENVA------TLQ 5669
Query: 93 VSDVSLSDEGQYTCSLFTMP-VKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTS 151
+ ++ G+Y C + ++ + A L VL + +G V G+ L CK +
Sbjct: 5670 FAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAG-PMTVTVGETCTLECKVA 5728
Query: 152 GSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGV---AVICRVD 208
G+ P + W+K+ K + + K N+ +SS V+R D G V V
Sbjct: 5729 GT-PELSVEWYKDGKLLTSSQKHKFSFYNK----ISSLRILSVERQDAGTYTFQVQNNVG 5783
Query: 209 HESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGG 268
S A V+ + + +T +K G IL C+ G P V W +
Sbjct: 5784 KSSCTAVVDVSDRAVPPSFTRRLKNTGGVL----GASCILECKVAGSS-PISVAWFHEKT 5838
Query: 269 ELPDPDRMVVSGRE----LNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLLP 324
++ + + + L + L+ +D G Y C A N G VL V + P+ +
Sbjct: 5839 KIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKE 5898
Query: 325 TTIIPSLTTATVTTTVAITTSP 346
+ L VT T I +P
Sbjct: 5899 PEPLEVLPGKNVTFTSVIRGTP 5920
Score = 49.7 bits (117), Expect = 5e-06
Identities = 65/295 (22%), Positives = 106/295 (35%), Gaps = 41/295 (13%)
Query: 36 VVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISVSD 95
+V G A+L C V + W F DKK +R ++ + + + + +
Sbjct: 3842 IVRGTNALLQCEVSGTGPFEISW---------FKDKKQIRSSKKYRLFSQKSLVCLEIFS 3892
Query: 96 VSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGSKP 155
+ +D G+Y C + K +L P + G + L GS+P
Sbjct: 3893 FNSADVGEYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEP 3952
Query: 156 AADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLNAT 215
+ + W K + I++ +K +N + + G C ++E+ + T
Sbjct: 3953 IS-VTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISF-----GGKYTCLAENEAGSQT 4006
Query: 216 PQVAMQVLEIHYTPSVKIIPSTPFPQ--EGQPLILTCESKGKPLPEPVLWTKDGGELPDP 273
V E+ KII Q G P L G P +P W KDG
Sbjct: 4007 -----SVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKP-KWYKDG------ 4054
Query: 274 DRMVVSGRELNILFLNKT-----------DNGTYRCEATNTIGQSSAEYVLIVHD 317
R +V+ ++ I F N D+G Y E +N +G SS E V D
Sbjct: 4055 -RPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLD 4108
Score = 49.7 bits (117), Expect = 5e-06
Identities = 55/233 (23%), Positives = 94/233 (40%), Gaps = 13/233 (5%)
Query: 93 VSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTSG 152
+ DV +S G+YTC + ++ P K V GD L +G
Sbjct: 3983 IPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAG 4042
Query: 153 SKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESL 212
+ P +W+K+ + + K + N V+ + + D G + +E
Sbjct: 4043 T-PELKPKWYKDGRPLVASKKYRISFKNN----VAQLKFYSAELHDSGQYTF-EISNEVG 4096
Query: 213 NATPQVAMQVLEIHYTPS-VKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELP 271
+++ + VL+ P K + + G L C+ G LP V W KDG E+
Sbjct: 4097 SSSCETTFTVLDRDIAPFFTKPLRNVDSVVNGT-CRLDCKIAGS-LPMRVSWFKDGKEIA 4154
Query: 272 DPDRMVVSGRE----LNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPN 320
DR ++ E L I+ ++ D G + C ATN++G + LIV + P+
Sbjct: 4155 ASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPS 4207
Score = 48.5 bits (114), Expect = 1e-05
Identities = 72/313 (23%), Positives = 119/313 (38%), Gaps = 53/313 (16%)
Query: 38 EGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVS 97
EGG C+++ D ++ Q T YF ++ + E+ + + V D++
Sbjct: 31581 EGGHVKYVCKIENYDQST-------QVTWYFGVRQLENSEKYEITYEDGVAI-LYVKDIT 31632
Query: 98 LSDEGQYTCS-------------LFTMPVKTSKAY---------------LTVLGVPEKP 129
D+G Y C LF V+ Y + +L P +
Sbjct: 31633 KLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEF 31692
Query: 130 QISGFSSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIK----DVKYLKEEDANRKTFT 185
+ ++ G+ ++ T P + W+K+ ++IK D KY E D T
Sbjct: 31693 TLPLYNKTAYVGENVRFGV-TITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLT 31751
Query: 186 VSS-TLDFRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYT--PSVKIIPSTPFPQE 242
++S T D D ++ V + +S A V + T P K + + QE
Sbjct: 31752 INSVTTD---DDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQE 31808
Query: 243 GQPLILTCESKGKPLPEPVLWTKDGGELP-DPDRMVV-SGRELNILFLNKT---DNGTYR 297
GQ + G P P + W KDG L P+ ++ G + L + T D G YR
Sbjct: 31809 GQSVCFEIRVSGIP-PPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYR 31867
Query: 298 CEATNTIGQSSAE 310
ATNT G +S +
Sbjct: 31868 VTATNTAGSTSCQ 31880
Score = 47.8 bits (112), Expect = 2e-05
Identities = 56/259 (21%), Positives = 101/259 (38%), Gaps = 59/259 (22%)
Query: 110 TMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGSK-PAADIRWFKNDKEI 168
T P T K + P P+I+ F ++ +LTC S A ++ W+K+ K++
Sbjct: 32701 TKPTPTEKVQHLPVSAP--PKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKL 32758
Query: 169 KDVKYLKEEDANRKTFTVSSTLDFRVDR---SDDGVAVICRVDHESLNATPQVAMQVL-- 223
K+ + + ++ T + +++ SD G +C + E T + +Q +
Sbjct: 32759 KENGHFQFH------YSADGTYELKINNLTESDQG-EYVCEISGEG--GTSKTNLQFMGQ 32809
Query: 224 ---EIHY------------------TPSVKIIPSTPFPQEGQPLILT------------- 249
IH T + K P P P +P+I+T
Sbjct: 32810 AFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVA 32869
Query: 250 ---CESKGKPLPEPVLWTKDGGELPDPDRMVVS----GRELNILFLNKTDNGTYRCEATN 302
++ G+P P + WTKDG + + +S G L I + +D+G Y C N
Sbjct: 32870 KFAVKATGEPRPTAI-WTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKN 32928
Query: 303 TIGQSSAEYVLIVHDVPNT 321
+ G S+ L + + +T
Sbjct: 32929 SAGSVSSSCKLTIKAIKDT 32947
Score = 45.8 bits (107), Expect = 8e-05
Identities = 64/283 (22%), Positives = 108/283 (38%), Gaps = 29/283 (10%)
Query: 46 CRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVSLSDEGQYT 105
CR++ ++ + W + D L+D+ + ++ + S GQY
Sbjct: 7137 CRINGSEPLQVSW---------YKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYN 7187
Query: 106 CSLFTMPVKTSKAYLTVLGVPEKP---QISGFSSPVMEGDLMQLTCKTSGSKPAADIRWF 162
CS S + +L E P + S + G+ C +G+ P I W
Sbjct: 7188 CSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIK-ITWA 7246
Query: 163 KNDKEIKDV-KYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQ 221
K+++EI+ Y N T TV +V + D G + S A
Sbjct: 7247 KDNREIRPGGNYKMTLVENTATLTV-----LKVGKGDAGQYTC----YASNIAGKDSCSA 7297
Query: 222 VLEIHYTPS-VKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRM---- 276
L + P +K + + ++ + C+ G P + VLW KD E+ + +
Sbjct: 7298 QLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIK-VLWYKDETEIQESSKFRMSF 7356
Query: 277 VVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
V S L + L+ D+G Y CEA N G +S+ L V + P
Sbjct: 7357 VDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPP 7399
Score = 45.8 bits (107), Expect = 8e-05
Identities = 39/119 (32%), Positives = 54/119 (45%), Gaps = 9/119 (7%)
Query: 206 RVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTK 265
R D SL A P VA ++ P VK S+ Q GQ L + G+P P + WTK
Sbjct: 23211 RSDPRSL-AVPIVAKDLV---IEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPT-ITWTK 23265
Query: 266 DGGELPDPDRMVVSGR----ELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPN 320
DG L R+ V+ L+I +K D G Y N +GQ +A ++ D P+
Sbjct: 23266 DGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPD 23324
Score = 45.4 bits (106), Expect = 1e-04
Identities = 66/267 (24%), Positives = 106/267 (39%), Gaps = 24/267 (8%)
Query: 61 PAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVSLSDEGQYTCSLFTMPVKTS--KA 118
P + +F D LR R H +S+ + +D G+Y C + T V +S A
Sbjct: 4420 PPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRV-TNEVGSSICSA 4478
Query: 119 YLTVLGVPE-KPQISGFSSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEE 177
+T+ P +I SS + G GS P + W K+ EI E+
Sbjct: 4479 RVTLREPPSFIKKIESTSS--LRGGTAAFQATLKGSLPIT-VTWLKDSDEI------TED 4529
Query: 178 DANRKTF--TVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIP 235
D R TF V+S ++ DG +C+ ++ A Q +L + ++
Sbjct: 4530 DNIRMTFENNVASLYLSGIEVKHDG-KYVCQAKND---AGIQRCSALLSVKEPATITEEA 4585
Query: 236 STPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGRE----LNILFLNKT 291
+ +G P L + G W KDG EL + +S + L I+ K
Sbjct: 4586 VSIDVTQGDPATLQVKFSGTK-EITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKK 4644
Query: 292 DNGTYRCEATNTIGQSSAEYVLIVHDV 318
D+G Y E N +G+SS + + V D+
Sbjct: 4645 DSGEYTFEVQNDVGRSSCKARINVLDL 4671
Score = 45.4 bits (106), Expect = 1e-04
Identities = 56/255 (21%), Positives = 101/255 (39%), Gaps = 28/255 (10%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSI 91
Q+VT+ EG T +TC Q+S P ++ +F + + L+ +
Sbjct: 8752 QDVTLKEGQTCTMTC----------QFSVPNVKSEWFRNGRILKPQGRHKTEVEHKVHKL 8801
Query: 92 SVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKP-QISGFSSPVMEGDLMQLTCKT 150
+++DV D+GQYTC + L + +P Q + ++ + T +
Sbjct: 8802 TIADVRAEDQGQYTCKYEDLETSAE------LRIEAEPIQFTKRIQNIVVSEHQSATFEC 8855
Query: 151 SGSKPAADIRWFKNDKEI-KDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGV-AVICRVD 208
S A + W+K E+ + KY D T+ + V D+GV +VI R++
Sbjct: 8856 EVSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHN-----VTPDDEGVYSVIARLE 8910
Query: 209 -HESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPL---PEPVLWT 264
+T ++ + EI IP + P P+ + P+ P P+L
Sbjct: 8911 PRGEARSTAELYLTTKEIKLELKPPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLP 8970
Query: 265 KDGGELPDPDRMVVS 279
+ P P R+ V+
Sbjct: 8971 TPEEKKPPPKRIEVT 8985
Score = 45.4 bits (106), Expect = 1e-04
Identities = 42/184 (22%), Positives = 80/184 (43%), Gaps = 22/184 (11%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSI 91
+++ +E + C+V++ N +L+W+ ++ + DNR+ R ++ +
Sbjct: 12741 KDIETMEKKSVTFWCKVNRL-NVTLKWTKNGEEVPF--------DNRVSY-RVDKYKHML 12790
Query: 92 SVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTS 151
++ D DEG+Y + T S A L ++ P + V E D +C+ S
Sbjct: 12791 TIKDCGFPDEGEY---IVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQLS 12847
Query: 152 GSKPAADIRWFKNDKEIKD-VKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHE 210
K A+++W++N +EIK+ KY E+D + + R DD C V+
Sbjct: 12848 REK--ANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDC------RLDDECEYACGVEDR 12899
Query: 211 SLNA 214
A
Sbjct: 12900 KSRA 12903
Score = 45.1 bits (105), Expect = 1e-04
Identities = 67/316 (21%), Positives = 129/316 (40%), Gaps = 48/316 (15%)
Query: 1 MFVLFLCNLSLV-----PAAASKNKVKGSQGQFPLT-----QNVTVVEGGTAILTCRVDQ 50
+ +L C L + AA +K+ + PL +V V E A C V +
Sbjct: 11806 ILILHNCQLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSR 11865
Query: 51 NDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVSLSDEGQYTCSLFT 110
T +W Q+ D+R EL++ S+ + + DE +Y +F
Sbjct: 11866 EPKT-FRWLKGTQEIT--------GDDRFELIKDGTKH-SMVIKSAAFEDEAKY---MFE 11912
Query: 111 MPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGSKPAAD---IRWFKNDKE 167
K + L + G+ K F +P+ + + + + D ++WFKND+
Sbjct: 11913 AEDKHTSGKLIIEGIRLK-----FLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQR 11967
Query: 168 IKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHY 227
+ + + +D + + ++ F+ D S D + I RV+ +++ ++ + + ++
Sbjct: 11968 LHTTRSVSMQDEGK-----THSITFK-DLSIDDTSQI-RVEAMGMSSEAKLTVLEGDPYF 12020
Query: 228 TPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGEL-PDPDRMVVSGRELNIL 286
T ++ E +IL CE PV W KDG E+ P + ++ + + +L
Sbjct: 12021 TGKLQDYTGV----EKDEVILQCEI--SKADAPVKWFKDGKEIKPSKNAVIKADGKKRML 12074
Query: 287 FLN---KTDNGTYRCE 299
L K+D G Y C+
Sbjct: 12075 ILKKALKSDIGQYTCD 12090
Score = 45.1 bits (105), Expect = 1e-04
Identities = 66/295 (22%), Positives = 121/295 (41%), Gaps = 43/295 (14%)
Query: 7 CNLSLVPAAASKNKVKGSQGQFPLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTL 66
CNL++VP + PLT ++ V E A C + + +N ++W
Sbjct: 12365 CNLNVVPPHVEFLR--------PLT-DLQVREKEMARFECELSR-ENAKVKW-------- 12406
Query: 67 YFDDKKALRDNRIELVRASWHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVP 126
+ D + + + +++ + + ++ L DE +Y+C + T +TS LTVL
Sbjct: 12407 FKDGAEIKKGKKYDIISKGAVRILV-INKCLLDDEAEYSCEVRT--ARTS-GMLTVLEEE 12462
Query: 127 EKPQISGFSSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTV 186
+ + V E D ++L C+ S KP A++ W+K D+EI + + RK V
Sbjct: 12463 AVFTKNLANIEVSETDTIKLVCEVS--KPGAEVIWYKGDEEIIETGRYEILTEGRKRILV 12520
Query: 187 SSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTP-SVKIIPSTPFPQEGQP 245
+D CR+ + +V E P +++I+ EG+
Sbjct: 12521 IQNAHL-----EDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEIL-------EGEK 12568
Query: 246 LILTCESKGKPLPEPVLWTKDGGELPDPDR--MVVSGRELNILFLNKT--DNGTY 296
C + PV W +D L D+ ++ G++ ++ + T D GTY
Sbjct: 12569 AEFVCSISKESF--PVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTY 12621
Score = 44.3 bits (103), Expect = 2e-04
Identities = 64/277 (23%), Positives = 109/277 (39%), Gaps = 44/277 (15%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSI 91
++ TV EG TA+L C V + +N ++W + L + + D R+ +
Sbjct: 12292 EDQTVEEGATAVLECEVSR-ENAKVKWFKNGTEILKSKKYEIVADGRVR---------KL 12341
Query: 92 SVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSP-----VMEGDLMQL 146
+ D + D YTC +K + T + P F P V E ++ +
Sbjct: 12342 VIHDCTPEDIKTYTCD--------AKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARF 12393
Query: 147 TCKTSGSKPAADIRWFKNDKEI-KDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVIC 205
C+ S+ A ++WFK+ EI K KY + ++ L DD C
Sbjct: 12394 ECEL--SRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCL------LDDEAEYSC 12445
Query: 206 RVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTK 265
V + + + + E +T ++ I + E + L CE KP E V+W K
Sbjct: 12446 EV--RTARTSGMLTVLEEEAVFTKNLANIEVS----ETDTIKLVCE-VSKPGAE-VIWYK 12497
Query: 266 DGGELPDPDR--MVVSGRELNILFLNK--TDNGTYRC 298
E+ + R ++ GR+ ++ N D G Y C
Sbjct: 12498 GDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNC 12534
Score = 44.3 bits (103), Expect = 2e-04
Identities = 32/85 (37%), Positives = 44/85 (51%), Gaps = 6/85 (7%)
Query: 243 GQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSG----RELNILFLNKTDNGTYRC 298
G+ L + G+P+P V WTK+ GEL D DR+V+ EL I + D+G Y
Sbjct: 15119 GKTLRIPAVVTGRPVPTKV-WTKEEGEL-DKDRVVIDNVGTKSELIIKDALRKDHGRYVI 15176
Query: 299 EATNTIGQSSAEYVLIVHDVPNTLL 323
ATN+ G A + V DVP +L
Sbjct: 15177 TATNSCGSKFAAARVEVFDVPGPVL 15201
Score = 43.5 bits (101), Expect = 4e-04
Identities = 70/329 (21%), Positives = 125/329 (37%), Gaps = 54/329 (16%)
Query: 38 EGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDN--------RIELVRASWHEL 89
+GG I VD+ + SL+W+ + + +D + + R+ V A+ +
Sbjct: 29266 DGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSE 29325
Query: 90 SISVSDVSLSDEGQYTCSLFTMP--VKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLT 147
S+ E YT + P V T+K +++ ++ P+ +G
Sbjct: 29326 PSEASNFISCREPSYTPGPPSAPRVVDTTKHSISL----------AWTKPMYDG------ 29369
Query: 148 CKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRV 207
DI + + + KD N T+ +T +F V G RV
Sbjct: 29370 --------GTDIVGYVLEMQEKDTDQWYRVHTNA---TIRNT-EFTVPDLKMGQKYSFRV 29417
Query: 208 DHESLNATPQVAMQVLEIHYTPSVKI--------IPSTPFPQEGQPLILTCESKGKPLPE 259
++ + + + EI ++I + T + G L L G+P P
Sbjct: 29418 AAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRP-PP 29476
Query: 260 PVLWTKDGGELPDPDRMVVSGRELNILFL----NKTDNGTYRCEATNTIGQSSAEYVLIV 315
+ W+K G +L R ++ E L + N+ D G Y EA N G+ SA ++ V
Sbjct: 29477 VITWSKQGIDLAS--RAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 29534
Query: 316 HDVPNTLLPTTIIPSLTTATVTTTVAITT 344
+D P P+ + ++ +VT T I T
Sbjct: 29535 YDTPGP-CPSVKVKEVSRDSVTITWEIPT 29562
Score = 43.5 bits (101), Expect = 4e-04
Identities = 57/235 (24%), Positives = 98/235 (41%), Gaps = 30/235 (12%)
Query: 112 PVKTSKAYLTVLGVPEKPQISGFSSPVME--GDLMQLTCKTSGSKPAADIRWFKNDKE-I 168
P +T+ + T L E P I V G+ QL+C+ G +P DI+W++ KE I
Sbjct: 30516 PRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVG-RPLPDIKWYRFGKELI 30574
Query: 169 KDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHE--SLNATPQVAMQVLEIH 226
+ KY D T TV + ++ D+GV C +E + + ++ +Q
Sbjct: 30575 QSRKYKMSSDGRTHTLTVMTE-----EQEDEGVYT-CIATNEVGEVETSSKLLLQA---- 30624
Query: 227 YTPSVKIIPSTPFPQE-----GQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGR 281
TP P P ++ G L L G+P+P + W L + + + +
Sbjct: 30625 -TPQFH--PGYPLKEKYYGAVGSTLRLHVMYIGRPVPA-MTWFHGQKLLQNSENITIENT 30680
Query: 282 E--LNILFLN---KTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLLPTTIIPSL 331
E +++ N KT G Y+ + +N G A + + D P+ +I +L
Sbjct: 30681 EHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEAL 30735
Score = 43.1 bits (100), Expect = 5e-04
Identities = 73/329 (22%), Positives = 131/329 (39%), Gaps = 76/329 (23%)
Query: 24 SQGQFPLTQNVTVVEGGTAILTCRVDQNDNTSLQW----SNPAQQTLYFDDKKALRDNRI 79
S+ Q + + V +GGT I+ ++Q + S+ W P Q T + K D +
Sbjct: 24517 SKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF---KTTGLDEGL 24573
Query: 80 ELVRASWHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLT--VLGVPEKPQISGFSSP 137
E +E +S ++ + P K S+ ++ P +P+ +
Sbjct: 24574 E------YEFKVSAENIVGIGK----------PSKVSECFVARDPCDPPGRPE-----AI 24612
Query: 138 VMEGDLMQLTCKTSGSKPAAD-----IRWFKNDKEIKDVKYLKEEDAN--RKTFTVSSTL 190
V+ + + L K KPA D + K++ D +++K N FTVS +
Sbjct: 24613 VITRNNVTLKWK----KPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLV 24668
Query: 191 D-----FRV----------DRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIP 235
+ FRV + SD A+ R + ++ NA+ L+ Y + +
Sbjct: 24669 EDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNAS-------LDPKYKDVIVV-- 24719
Query: 236 STPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPD-----RMVVSGRELNILFLNK 290
G+ +L + +GKP+P+ V+W+KDG EL + + + L + +
Sbjct: 24720 -----HAGETFVLEADIRGKPIPD-VVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 24773
Query: 291 TDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
TD G Y + +N G S + V D P
Sbjct: 24774 TDGGQYILKLSNVGGTKSIPITVKVLDRP 24802
Score = 42.0 bits (97), Expect = 0.001
Identities = 60/260 (23%), Positives = 106/260 (40%), Gaps = 37/260 (14%)
Query: 99 SDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGSKPAAD 158
+D G +CS+ + VK ++ L E + S ++L C+ +G+ P +
Sbjct: 4938 NDAGTASCSI-ELKVKEPPTFIRELKPVEVVKYSD----------VELECEVTGTPPF-E 4985
Query: 159 IRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHE--SLNATP 216
+ W KN++EI+ K D F + T + D SD G C V +E S + +
Sbjct: 4986 VTWLKNNREIRSSKKYTLTD-RVSVFNLHIT---KCDPSDTG-EYQCIVSNEGGSCSCST 5040
Query: 217 QVAMQVLEIHYTPS-VKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDR 275
+VA++ PS +K I +T + + + P+ + W KD L + D
Sbjct: 5041 RVALKE-----PPSFIKKIENTTTVLKSSATFQSTVAGSPPIS--ITWLKDDQILDEDDN 5093
Query: 276 MVVSGRE----LNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLLPTTIIPSL 331
+ +S + L I ++ +G Y C+A N G L+V + P I+
Sbjct: 5094 VYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQE------PAQIVEKA 5147
Query: 332 TTATVTTTVAITTSPTTSAT 351
+ VT +T + T
Sbjct: 5148 KSVDVTEKDPMTLECVVAGT 5167
Score = 42.0 bits (97), Expect = 0.001
Identities = 43/179 (24%), Positives = 73/179 (40%), Gaps = 35/179 (19%)
Query: 154 KPAADIRWFKNDKE-IKDVKYLKEEDANRKTFTVSSTLD-----FRVDRSDDGVAVICRV 207
+ + D W K++KE IKD K FT+ L+ FRV ++
Sbjct: 30470 RQSGDSAWKKSNKERIKD-----------KQFTIGGLLEATEYEFRVFAENE-------- 30510
Query: 208 DHESLNATPQVAMQV---LEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWT 264
L+ + AM + L P ++ + G+ L+C+ G+PLP+ + W
Sbjct: 30511 --TGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPD-IKWY 30567
Query: 265 KDGGELPDPDRMVVSG----RELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
+ G EL + +S L ++ + D G Y C ATN +G+ L++ P
Sbjct: 30568 RFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATP 30626
Score = 41.6 bits (96), Expect = 0.001
Identities = 42/147 (28%), Positives = 69/147 (46%), Gaps = 18/147 (12%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIE-LVRASWHELS 90
++V V+EG A+L C+V D TS++W Y +D++ D+R++ +V+ + L
Sbjct: 2452 KDVNVIEGTKAVLECKVSVPDVTSVKW--------YLNDEQIKPDDRVQAIVKGTKQRLV 2503
Query: 91 ISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKT 150
I+ + SDEG Y L V+T+ L+V EK +I + + + +
Sbjct: 2504 INRTHA--SDEGPY--KLIVGRVETN-CNLSV----EKIKIIRGLRDLTCTETQNVVFEV 2554
Query: 151 SGSKPAADIRWFKNDKEIKDVKYLKEE 177
S D+ W DKEIK K E
Sbjct: 2555 ELSHSGIDVLWNFKDKEIKPSSKYKIE 2581
Score = 41.6 bits (96), Expect = 0.001
Identities = 56/231 (24%), Positives = 86/231 (37%), Gaps = 32/231 (13%)
Query: 140 EGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDR--- 196
EG + C+ SG+ + W+ DK+IK ++ + T+ + + D
Sbjct: 3358 EGQPARFQCRVSGTD--LKVSWYSKDKKIKPSRFFRMTQFE-DTYQLEIAEAYPEDEGTY 3414
Query: 197 ---SDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLIL----- 248
+ + V + + SL A + + +E +K P E + L
Sbjct: 3415 TFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAK 3474
Query: 249 -TCESKGKPLPEPVLWTKDGGELPDPDRMVVSGRE----LNILFLNKTDNGTYRCEATNT 303
TCE + P W K G E+ + D+ + + L IL D G Y C+A+N
Sbjct: 3475 FTCEIQSAPNVR-FQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNE 3533
Query: 304 IGQSSAEYVLIVHDV-PNTLLPTTIIPSLTT---------ATVTTTVAITT 344
G S L V + P T L SLTT TVT T I T
Sbjct: 3534 YGSVSCTATLTVTEAYPPTFLSRP--KSLTTFVGKAAKFICTVTGTPVIET 3582
Score = 40.8 bits (94), Expect = 0.002
Identities = 31/95 (32%), Positives = 46/95 (48%), Gaps = 5/95 (5%)
Query: 229 PSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVV----SGRELN 284
PS+K+ +T Q G+ L + G+P P + W KDG L R+ V + L+
Sbjct: 24312 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPN-ISWVKDGEPLKQTTRVNVEETATSTVLH 24370
Query: 285 ILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
I NK D G Y ATN+ G ++ +IV + P
Sbjct: 24371 IKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKP 24405
Score = 40.4 bits (93), Expect = 0.003
Identities = 54/233 (23%), Positives = 93/233 (39%), Gaps = 18/233 (7%)
Query: 91 ISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEK--PQISGFSSPVMEGDLMQLTC 148
+ + DV S G+YTC + K S + P K +++ +S + +G + L
Sbjct: 7832 LELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYS--IEKGKPLILEG 7889
Query: 149 KTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVD 208
+G+ P + + W KN + + N T S+ L+ +D C ++
Sbjct: 7890 TFTGTPPIS-VTWKKN-----GINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIE 7943
Query: 209 HESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGG 268
+ S + + +LE Y VK + G L C+ G P V W K
Sbjct: 7944 NASGKDSCSAQILILEPPY--FVKQLEPVKV-SVGDSASLQCQLAGTP-EIGVSWYKGDT 7999
Query: 269 EL-PDPDRMVVSGRELNILFLNK---TDNGTYRCEATNTIGQSSAEYVLIVHD 317
+L P + + L N+ D+G Y C+A N++G+ SA L V +
Sbjct: 8000 KLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQE 8052
Score = 38.9 bits (89), Expect = 0.009
Identities = 70/306 (22%), Positives = 122/306 (39%), Gaps = 46/306 (15%)
Query: 38 EGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVS 97
+GG+ I +++ + SL+W ++ +Y D + E + + + + +S
Sbjct: 26009 DGGSEISGYIIERREKNSLRWVRVNKKPVY--DLRVKSTGLREGCEYEYRVYAENAAGLS 26066
Query: 98 LSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQI--SGFSS-------PVMEGDLMQLTC 148
L E T P+ ++ + + P KP+I SG ++ P+ +G +T
Sbjct: 26067 LPSE--------TSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGA-PITG 26117
Query: 149 KTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVD 208
T K + D W + + ++ +Y T + FRV +S + V
Sbjct: 26118 YTVEYKKSDDTDWKTSIQSLRGTEY------TISGLTTGAEYVFRV-KSVNKVGA----S 26166
Query: 209 HESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGG 268
S ++ PQ+A + E + T + G +T +G+P+P VLW+K
Sbjct: 26167 DPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPN-VLWSK--- 26222
Query: 269 ELPDPD---RMVV----SGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNT 321
PD D R V S L I N+ D+G Y N + +S V+ V D P
Sbjct: 26223 --PDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP 26280
Query: 322 LLPTTI 327
PT I
Sbjct: 26281 --PTNI 26284
Score = 38.9 bits (89), Expect = 0.009
Identities = 27/101 (26%), Positives = 44/101 (43%), Gaps = 5/101 (4%)
Query: 241 QEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRM----VVSGRELNILFLNKTDNGTY 296
+ G+ L + +G+P+P V W KDG E+ M V+ L + + G Y
Sbjct: 27971 KSGESLRIKALVQGRPVPR-VTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 28029
Query: 297 RCEATNTIGQSSAEYVLIVHDVPNTLLPTTIIPSLTTATVT 337
EA N G + AE + V D P ++ ++T +T
Sbjct: 28030 TVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 28070
Score = 38.5 bits (88), Expect = 0.012
Identities = 69/296 (23%), Positives = 117/296 (39%), Gaps = 38/296 (12%)
Query: 39 GGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVSL 98
G +AI C V + +T++ T + D +R++ A + + + DV L
Sbjct: 11133 GSSAIFECLV--SPSTAI--------TTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQL 11182
Query: 99 SDEGQYTCSL-FTMPVKTSKAYLTVLGVPEK-PQISGFSSPVMEGDLMQLTCKTSGSKPA 156
SD G+YTC L KTS A L V +P + + V++G + L+C+ + +
Sbjct: 11183 SDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKER-- 11240
Query: 157 ADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLNATP 216
D+ W KD K + E+ + ++ +DD A V E+ N
Sbjct: 11241 -DVVW------RKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLE 11293
Query: 217 -QVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELP-DPD 274
++V+E+ VK I +G + +K P + W K E+P +P+
Sbjct: 11294 CSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFACDIAKDTP---NIKWFKGYDEIPAEPN 11350
Query: 275 RMVVSGRELNILFLN-----KTDNGTYRCE-------ATNTIGQSSAEYVLIVHDV 318
R+ N L+L D Y E A T+G+ E + + DV
Sbjct: 11351 DKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVELLKPIEDV 11406
Score = 37.7 bits (86), Expect = 0.021
Identities = 62/307 (20%), Positives = 122/307 (39%), Gaps = 31/307 (10%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSI 91
QN+ ++EG A C + + ++ +QW DDK ++ +++ A + +
Sbjct: 12559 QNLEILEGEKAEFVCSISK-ESFPVQWKR--------DDKTLESGDKYDVI-ADGKKRVL 12608
Query: 92 SVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTS 151
V D +L D G Y + + + A+LTV+ EK +I + ++
Sbjct: 12609 VVKDATLQDMGTY---VVMVGAARAAAHLTVI---EKLRIVVPLKDTRVKEQQEVVFNCE 12662
Query: 152 GSKPAADIRWFKNDKEIKDV-KYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHE 210
+ A +WF+N++ I D KY+ + T + D +D + + E
Sbjct: 12663 VNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIR---DAHLDDQANYNVSLTNHRGE 12719
Query: 211 SLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGEL 270
++ + + ++ ++ +K I + E + + C K L + WTK+G E+
Sbjct: 12720 NVKSAANLIVEEEDLRIVEPLKDIET----MEKKSVTFWC--KVNRLNVTLKWTKNGEEV 12773
Query: 271 PDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLLPTTIIPS 330
P +R+ + + K E T GQ + L++ + PT +
Sbjct: 12774 PFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEA-----PTEFVEH 12828
Query: 331 LTTATVT 337
L TVT
Sbjct: 12829 LEDQTVT 12835
Score = 36.6 bits (83), Expect = 0.046
Identities = 33/117 (28%), Positives = 52/117 (44%), Gaps = 8/117 (6%)
Query: 243 GQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGRELNILF--LNKTDNGTYRCEA 300
G L L KG+P PE V W K GE+ D + V+ +++ +N+ D+G Y
Sbjct: 22957 GGSLRLFVPIKGRPTPE-VKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTL 23015
Query: 301 TNTIGQSSAEYVLIVHDVPNTLLPTTIIPSLTTATVTTTVAITTSPTTSATTSSIRD 357
N+ G SA + V D P+ + + T +V+IT P S I++
Sbjct: 23016 ENSSGTKSAFVTVRVLDTPSPPVNLKV-----TEITKDSVSITWEPPLLDGGSKIKN 23067
Score = 36.2 bits (82), Expect = 0.060
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 5/70 (7%)
Query: 254 GKPLPEPVLWTKDGGELPDPDRMVVSGRE----LNILFLNKTDNGTYRCEATNTIGQSSA 309
GKP+P V W KDG L + + ++ + L + +N+ D+G Y A N+ G SA
Sbjct: 19321 GKPMPT-VSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSA 19379
Query: 310 EYVLIVHDVP 319
L V D P
Sbjct: 19380 TIKLKVLDKP 19389
Score = 36.2 bits (82), Expect = 0.060
Identities = 27/124 (21%), Positives = 48/124 (38%), Gaps = 22/124 (17%)
Query: 242 EGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGRELNILF----LNKTDNGTYR 297
EG+ +C++ G+P+P V W + G L R V+ + F + +D G Y
Sbjct: 32574 EGESARFSCDTDGEPVPT-VTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYS 32632
Query: 298 CEATNTIGQSSAEYVLIVHDVPNTLLPTTIIPSLTTATVTTTVAITTSPTTSATTSSIRD 357
N+ G+ AE+ L + T A+T+ P + ++
Sbjct: 32633 VVVENSEGKQEAEFTLTIQKAR-----------------VTEKAVTSPPRVKSPEPRVKS 32675
Query: 358 PNAL 361
P A+
Sbjct: 32676 PEAV 32679
Score = 35.8 bits (81), Expect = 0.079
Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 7/92 (7%)
Query: 243 GQPLILTCESKGKPLPEPVLWTKD--GGELPDPDRMVVSGR----ELNILFLNKTDNGTY 296
G + L +GKP PE V WTKD +L R+ + R + ++ ++D G Y
Sbjct: 18216 GDTIRLEAGVRGKPFPE-VAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKY 18274
Query: 297 RCEATNTIGQSSAEYVLIVHDVPNTLLPTTII 328
ATNT G A + V D P + I+
Sbjct: 18275 VVTATNTAGSFVAYATVNVLDKPGPVRNLKIV 18306
Score = 35.8 bits (81), Expect = 0.079
Identities = 40/168 (23%), Positives = 72/168 (42%), Gaps = 22/168 (13%)
Query: 166 KEIKDVKYLKEEDAN--RKTFTVS-----STLDFRVDRSDDGVAVICRVDHESLNATPQV 218
+++ + ++LK +N FTVS + +FRV + A+ S + P
Sbjct: 21396 RDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAI-------SPPSEPSD 21448
Query: 219 AMQVLEIHYTPSVKI---IPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDR 275
A+ + P +K+ T + G+ L + G+P P + W+KDG EL +
Sbjct: 21449 AITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRP-PPTMEWSKDGKELEGTAK 21507
Query: 276 MVVSGRELNILFLNK----TDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
+ + + + +NK D+G Y ATN G + + + V D P
Sbjct: 21508 LEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRP 21555
Score = 35.4 bits (80), Expect = 0.10
Identities = 32/103 (31%), Positives = 44/103 (42%), Gaps = 7/103 (6%)
Query: 243 GQPLILTCES-KGKPLPEPVLWTKDGGELPDPDRMVVSGRE----LNILFLNKTDNGTYR 297
G ++L S GKPLP+ W+K G ++ D ++ L I + + D G Y
Sbjct: 20393 GDTIVLNAISILGKPLPKSS-WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYT 20451
Query: 298 CEATNTIGQSSAEYVLIVHDVPNTLLPTTII-PSLTTATVTTT 339
ATN G + V DVP P I S AT+T T
Sbjct: 20452 ITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWT 20494
Score = 35.0 bits (79), Expect = 0.13
Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 3/69 (4%)
Query: 253 KGKPLPEPVLWTKDGGELPDPDRMV--VSGRELNILFLNKTDNGTYRCEATNTIGQSSAE 310
KG+P PE + W+++ GE D ++ V+ +L+I ++ D G Y + N+ G SA
Sbjct: 24049 KGRPTPE-ITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAF 24107
Query: 311 YVLIVHDVP 319
+ V D P
Sbjct: 24108 VTVKVLDTP 24116
Score = 34.7 bits (78), Expect = 0.18
Identities = 29/112 (25%), Positives = 52/112 (46%), Gaps = 12/112 (10%)
Query: 241 QEGQPLILTCESKGKPLPEPVLWTKDGGELPDP-DRMVVSGRELNILFLNKT---DNGTY 296
++G + L G P P V + +DG E+ D + +L L + + D+GTY
Sbjct: 116 RQGSQVRLQVRVTGIPTPV-VKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174
Query: 297 RCEATNTIGQSSAEYVLIVHDVPNTLLPTTIIPSLTTATVTTTVAITTSPTT 348
ATN++G++++ L+V +P+ T T+ +T I+ S T
Sbjct: 175 SVNATNSVGRATSTAELLVQGEEE-------VPAKKTKTIVSTAQISESRQT 219
Score = 34.7 bits (78), Expect = 0.18
Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Query: 239 FPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVS--GRELNILFLNKTDNGTY 296
F ++G + LT KGKP P WTK+G ++ + S EL I ++ D+GTY
Sbjct: 30147 FVRQGGVIRLTIPIKGKPFP-ICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTY 30205
Query: 297 RCEATNTIGQSSAEYVLIVHDVPNT 321
N G+ + + V PN+
Sbjct: 30206 DLVLENKCGKKAVYIKVRVIGSPNS 30230
Score = 34.7 bits (78), Expect = 0.18
Identities = 34/130 (26%), Positives = 55/130 (42%), Gaps = 19/130 (14%)
Query: 243 GQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGRE----LNILFLNKTDNGTYRC 298
GQ + KP E V W +G EL + ++ + L IL + D+GTYR
Sbjct: 32388 GQNTRFILNVQSKPTAE-VKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRA 32446
Query: 299 EATNTIGQSS---------AEYVLIVHDVPNTLLPTTIIPSLTTATVTTTVAITTSPTTS 349
TN G++S +Y + +P ++ P LT T A+++ TS
Sbjct: 32447 VCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTR---TEAYAVSSFKKTS 32503
Query: 350 --ATTSSIRD 357
+SS+R+
Sbjct: 32504 EMEASSSVRE 32513
Score = 34.3 bits (77), Expect = 0.23
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Query: 242 EGQPLILTCESKGKPLPEPVLWTKDG-----GELPDPDRMVVSGR-ELNILFLNKTDNGT 295
EG G P+PE V W +DG LP GR +L I + K ++G
Sbjct: 19 EGSTATFEAHISGFPVPE-VSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGR 77
Query: 296 YRCEATNTIGQSSAEYVLIV 315
Y +ATN GQ+++ L+V
Sbjct: 78 YSLKATNGSGQATSTAELLV 97
Score = 33.9 bits (76), Expect = 0.30
Identities = 30/107 (28%), Positives = 47/107 (43%), Gaps = 6/107 (5%)
Query: 223 LEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGRE 282
LE Y P + P + EGQ + G+P+PE W DG ++ + V +E
Sbjct: 1451 LERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPE-TFWFHDGQQIVNDYTHKVVIKE 1509
Query: 283 -----LNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLLP 324
L I+ +D+G + A N G+SS +L V V + + P
Sbjct: 1510 DGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKP 1556
Score = 33.9 bits (76), Expect = 0.30
Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 5/81 (6%)
Query: 243 GQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSG----RELNILFLNKTDNGTYRC 298
G + L GKP P+ + WTK L R+ + + I+ ++D GTY
Sbjct: 13705 GTKIELPATVTGKPEPK-ITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYII 13763
Query: 299 EATNTIGQSSAEYVLIVHDVP 319
EA N G+++A + V D P
Sbjct: 13764 EAVNVCGRATAVVEVNVLDKP 13784
Score = 33.9 bits (76), Expect = 0.30
Identities = 23/81 (28%), Positives = 40/81 (49%), Gaps = 5/81 (6%)
Query: 243 GQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVV--SGRELN--ILFLNKTDNGTYRC 298
G L+L GKP P+ ++WTK EL +++ + +G+ I F +++D+G Y
Sbjct: 29062 GSDLVLDAAVGGKPEPK-IIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTL 29120
Query: 299 EATNTIGQSSAEYVLIVHDVP 319
N G + ++ V D P
Sbjct: 29121 TVKNASGTKAVSVMVKVLDSP 29141
Score = 33.5 bits (75), Expect = 0.39
Identities = 24/79 (30%), Positives = 34/79 (43%), Gaps = 3/79 (3%)
Query: 243 GQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVS--GRELNILFLNKTDNGTYRCEA 300
G L L+ KG P P+ V W K+ + P R+ V+ G +L I D G Y
Sbjct: 17233 GDTLRLSAIIKGVPFPK-VTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTV 17291
Query: 301 TNTIGQSSAEYVLIVHDVP 319
N G + ++V D P
Sbjct: 17292 ENPAGSKTVSVKVLVLDKP 17310
Score = 33.1 bits (74), Expect = 0.51
Identities = 75/325 (23%), Positives = 122/325 (37%), Gaps = 38/325 (11%)
Query: 26 GQFPLTQNVTVVEGGTAILTCRVDQNDNTS--LQWSNP-----AQQTLYFDDKKALRDNR 78
G+ + NV V++ + +V TS + W+ P +Q T Y +K+
Sbjct: 18685 GEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKR------ 18738
Query: 79 IELVRASWHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPE---KPQISGFS 135
E R +W ++ V S + + V Y GVP KP ++ S
Sbjct: 18739 -EADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGP--GVPTDVPKPVLA--S 18793
Query: 136 SPVMEGDLMQLTCKTSGSKPAADIRWFK--NDKEIKDVKYL-----KEEDANRKT-FTVS 187
P+ E D + T +K +A + W D K Y+ +E+ A+R T ++V
Sbjct: 18794 DPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVV 18853
Query: 188 STLDFRVDRSDDGVAVICRVDHESLNAT--PQVAMQVLEI--HYTPSVKIIPSTPFPQEG 243
L V +G RV + P+ A V E P ++P + G
Sbjct: 18854 KDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAG 18913
Query: 244 QPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVV----SGRELNILFLNKTDNGTYRCE 299
+ L + GKP P W K E+ + V S L I + + D+G Y
Sbjct: 18914 KKLRIEAHVYGKPHPT-CKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLT 18972
Query: 300 ATNTIGQSSAEYVLIVHDVPNTLLP 324
A N+ G + + ++V D P P
Sbjct: 18973 AENSSGTDTQKIKVVVMDAPGPPQP 18997
Score = 33.1 bits (74), Expect = 0.51
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 8/91 (8%)
Query: 253 KGKPLPEPVLWTKDGGELPDPDRMVVSGRELNILFL---NKTDNGTYRCEATNTIGQSSA 309
KG+P PE V W +D GE D + S +L + N+ D+G Y N+ G SA
Sbjct: 21885 KGRPAPE-VKWARDHGESLDK-ASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSA 21942
Query: 310 EYVLIVHDVPNTLLPTTI-IPSLTTATVTTT 339
+ V D P P + + +T +VT T
Sbjct: 21943 FVNVRVLDTPGP--PQDLKVKEVTKTSVTLT 21971
Score = 33.1 bits (74), Expect = 0.51
Identities = 30/113 (26%), Positives = 47/113 (41%), Gaps = 5/113 (4%)
Query: 229 PSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGRELNILFL 288
P+ K++ +T G+ L + G+P P V W KD L R+ E N L
Sbjct: 22148 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPA-VTWHKDNVPLKQTTRVNAESTENNSLLT 22206
Query: 289 NKT----DNGTYRCEATNTIGQSSAEYVLIVHDVPNTLLPTTIIPSLTTATVT 337
K D G Y + TN+ G++ +IV D P + +T ++T
Sbjct: 22207 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSIT 22259
Score = 33.1 bits (74), Expect = 0.51
Identities = 31/125 (24%), Positives = 49/125 (39%), Gaps = 6/125 (4%)
Query: 218 VAMQVLEIHYTPSVKIIPS-TPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRM 276
V +Q L + T + +P T G+P+ L G+P P W G +L + +R+
Sbjct: 29727 VTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRP-PPAASWFFAGSKLRESERV 29785
Query: 277 VVSGR----ELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLLPTTIIPSLT 332
V +L I D G Y E N G +S +I+ D P I +
Sbjct: 29786 TVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEID 29845
Query: 333 TATVT 337
++T
Sbjct: 29846 ATSIT 29850
Score = 32.7 bits (73), Expect = 0.67
Identities = 61/282 (21%), Positives = 110/282 (39%), Gaps = 39/282 (13%)
Query: 28 FPLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWH 87
F Q+ TV +G A RV + +W Y + K R +RI +
Sbjct: 2081 FERIQSQTVGQGSDAHFRVRVVGKPDPECEW--------YKNGVKIERSDRIYWYWPEDN 2132
Query: 88 ELSISVSDVSLSDEGQYTCSLFTMPVKTSK-AYLTVLGVPEKPQISGFSSPVM-----EG 141
+ + DV+ D + +TS A+L V + Q+ F+ + E
Sbjct: 2133 VCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLV----QAKQLITFTQELQDVVAKEK 2188
Query: 142 DLMQLTCKTSGSKPAADIRWFKNDKEIKD-VKYLKEEDANRKTFTVSSTLDFRVDRSDDG 200
D M T + S+P ++W+K+ E+ + KY D RK +S +D SD
Sbjct: 2189 DTMA-TFECETSEPFVKVKWYKDGMEVHEGDKYRMHSD--RKVHFLSI---LTIDTSDAE 2242
Query: 201 VAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQ-PLILTCES-KGKPLP 258
V+ E++ T ++ ++ + + ++ I P G+ I++ E+ +GK
Sbjct: 2243 DYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDI-EVPESYSGELECIVSPENIEGK--- 2298
Query: 259 EPVLWTKDGGELPDPDRMVVSGR----ELNILFLNKTDNGTY 296
W + EL + ++ R L + + K D G Y
Sbjct: 2299 ----WYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEY 2336
Score = 32.7 bits (73), Expect = 0.67
Identities = 77/341 (22%), Positives = 135/341 (39%), Gaps = 81/341 (23%)
Query: 13 PAAASKNKVKG-SQGQFPLTQNVTVVEGGTAILTCRVDQNDNTSLQWS------------ 59
PAA K +VK S+G L + +++GG+ I+ +++ D T WS
Sbjct: 27366 PAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFK 27425
Query: 60 --NPAQQTLYFDDKKALRDNRI---------ELVRASWHELSISVSDVSLSDEGQYTCSL 108
+ +++T +F + L +N I E V+A+ E+ + D+S+ D + + L
Sbjct: 27426 LIDLSEKTPFF--FRVLAENEIGIGEPCETTEPVKAA--EVPAPIRDLSMKDSTKTSVIL 27481
Query: 109 -FTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKE 167
+T P + +T V K + + T +G +I
Sbjct: 27482 SWTKPDFDGGSVITEYVVERKGK-------------GEQTWSHAGISKTCEI-------- 27520
Query: 168 IKDVKYLKEEDANRKTFTVSSTLDFRV-DRSDDGVAVICRVDHESLNATPQVAMQVLEIH 226
+V LKE+ S L+FRV +++ G++ + + P + V E+
Sbjct: 27521 --EVSQLKEQ----------SVLEFRVFAKNEKGLS-------DPVTIGP---ITVKELI 27558
Query: 227 YTPSVKI--IPSTPFP-QEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGRE- 282
TP V + IP + G + L KGKP P + W KDG L + + + S E
Sbjct: 27559 ITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPS-ISWLKDGLPLKESEFVRFSKTEN 27617
Query: 283 ---LNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPN 320
L+I K G Y N + + + +I P+
Sbjct: 27618 KITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPS 27658
Score = 32.3 bits (72), Expect = 0.87
Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 10/79 (12%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSI 91
Q+ T VE IL C + + D ++W F D K ++ ++ +++A + +
Sbjct: 12025 QDYTGVEKDEVILQCEISKAD-APVKW---------FKDGKEIKPSKNAVIKADGKKRML 12074
Query: 92 SVSDVSLSDEGQYTCSLFT 110
+ SD GQYTC T
Sbjct: 12075 ILKKALKSDIGQYTCDCGT 12093
Score = 32.0 bits (71), Expect = 1.1
Identities = 20/82 (24%), Positives = 37/82 (45%), Gaps = 4/82 (4%)
Query: 241 QEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGRE----LNILFLNKTDNGTY 296
+EG + C+ + V W +L + ++ ++ + L + + K D+GTY
Sbjct: 31580 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 31639
Query: 297 RCEATNTIGQSSAEYVLIVHDV 318
RC+ N G+ S+ L V V
Sbjct: 31640 RCKVVNDYGEDSSYAELFVKGV 31661
Score = 31.6 bits (70), Expect = 1.5
Identities = 38/171 (22%), Positives = 72/171 (42%), Gaps = 31/171 (18%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSI 91
Q++ V E + L C V +N +W Y +D + L+ N + + ++
Sbjct: 2274 QDIEVPESYSGELECIVSP-ENIEGKW--------YHNDVE-LKSNGKYTITSRRGRQNL 2323
Query: 92 SVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTS 151
+V DV+ D+G+Y+ F + K + L + P V EGD++QL K
Sbjct: 2324 TVKDVTKEDQGEYS---FVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKV- 2379
Query: 152 GSKPAADIRWFKNDKEIKD----------------VKYLKEEDANRKTFTV 186
S + + W K+ +E++ ++ + +EDA +FT+
Sbjct: 2380 -SLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTI 2429
Score = 31.6 bits (70), Expect = 1.5
Identities = 20/71 (28%), Positives = 29/71 (40%), Gaps = 5/71 (7%)
Query: 253 KGKPLPEPVLWTKDGGELPDPDRMVVSGRELNILFLNKT----DNGTYRCEATNTIGQSS 308
+G P+P WT DG E+ + V + + K D G Y+ +N G +
Sbjct: 17535 RGVPVPT-AKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKT 17593
Query: 309 AEYVLIVHDVP 319
L V DVP
Sbjct: 17594 VAVHLTVLDVP 17604
Score = 31.6 bits (70), Expect = 1.5
Identities = 66/302 (21%), Positives = 116/302 (38%), Gaps = 43/302 (14%)
Query: 36 VVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWH-ELSISVS 94
+ +GG+ I +++ D SL W ++T +RD R ++ + + + V
Sbjct: 27090 IADGGSDISGYFLEKRDKKSLGWFKVLKET--------IRDTRQKVTGLTENSDYQYRVC 27141
Query: 95 DVSLSDEGQYTCSLFTMPVKTSKAY--LTVLGVPEKPQIS---------GFSSPVMEGDL 143
V+ + +G F+ P + KA + G P K +I+ G+S PV +G
Sbjct: 27142 AVNAAGQGP-----FSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDG-- 27194
Query: 144 MQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAV 203
GS + + +E ++ + + R T V S L V+ AV
Sbjct: 27195 --------GSAVTGYVVEIRQGEE-EEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAV 27245
Query: 204 ICRVDHESLNAT-PQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVL 262
C E + P A +LE + ++ + G+ + + KG+P P V
Sbjct: 27246 NCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRP-PPTVT 27304
Query: 263 WTKDGGELPDPDRMVVSGRE----LNILFLNKTDNGTYRCEATNTIGQSSAEYVLI-VHD 317
W KD L R + + L I + + D G Y N +G+ + V + V D
Sbjct: 27305 WRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLD 27364
Query: 318 VP 319
P
Sbjct: 27365 TP 27366
Score = 31.2 bits (69), Expect = 1.9
Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 5/82 (6%)
Query: 242 EGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVS----GRELNILFLNKTDNGTYR 297
EG+ L + + P+P V W KDG E+ DR+ + L + + D G Y
Sbjct: 14400 EGEKLSIPVPFRAVPVPT-VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYT 14458
Query: 298 CEATNTIGQSSAEYVLIVHDVP 319
N +G ++A + V +P
Sbjct: 14459 ITLENKLGSATASINVKVIGLP 14480
Score = 31.2 bits (69), Expect = 1.9
Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 5/70 (7%)
Query: 254 GKPLPEPVLWTKDGGELPDPDRM----VVSGRELNILFLNKTDNGTYRCEATNTIGQSSA 309
G+P P V W K L R+ + LNI ++D+G Y A N +G+
Sbjct: 21091 GRPKPT-VTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGD 21149
Query: 310 EYVLIVHDVP 319
+ VHD+P
Sbjct: 21150 VITIQVHDIP 21159
Score = 31.2 bits (69), Expect = 1.9
Identities = 45/192 (23%), Positives = 86/192 (44%), Gaps = 28/192 (14%)
Query: 52 DNTSLQWSNPA-----QQTLYFDDKKALRDNRIELVRASWHELSISVSDVS-LSDEGQYT 105
++ SL W PA + T Y +++ L D R +AS+ ++ + +S L+ QY
Sbjct: 26782 NSVSLSWQQPAFDGGSKITGYIVERRDLPDGR--WTKASFTNVTETQFIISGLTQNSQYE 26839
Query: 106 CSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVME-------------GDLMQLTCKTSG 152
+F S + + + P I + PV++ G ++L SG
Sbjct: 26840 FRVFARNAVGSISNPSEVVGPITC-IDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISG 26898
Query: 153 SKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESL 212
KPA I W+K+DKE++ + E+ T ++S L DR + G + ++ +
Sbjct: 26899 -KPAPTIEWYKDDKELQTNALVCVEN----TTDLASILIKDADRLNSGCYEL-KLRNAMG 26952
Query: 213 NATPQVAMQVLE 224
+A+ + +Q+L+
Sbjct: 26953 SASATIRVQILD 26964
Score = 30.8 bits (68), Expect = 2.5
Identities = 37/161 (22%), Positives = 70/161 (43%), Gaps = 19/161 (11%)
Query: 178 DANRKTFTVSSTLDFRVDRSDDGVAVICRVD--HESLNATPQVAMQVL--EIHYTPSVKI 233
D R + T F V+ D+ RV +E + P + + V+ + P++K+
Sbjct: 15340 DFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKL 15399
Query: 234 IPS----TPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDP-DRMVVSGRE------ 282
S T + G+P+ + + G P+P+ + W+K+ + P D + ++ E
Sbjct: 15400 RLSVRGDTIKVKAGEPVHIPADVTGLPMPK-IEWSKNETVIEKPTDALQITKEEVSRSEA 15458
Query: 283 ---LNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPN 320
L+I + D GTY A+N +G + V+D P+
Sbjct: 15459 KTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 15499
Score = 30.0 bits (66), Expect = 4.3
Identities = 47/241 (19%), Positives = 93/241 (38%), Gaps = 23/241 (9%)
Query: 40 GTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVSLS 99
G LTC QN ++ S+ L+ K ++ + + A ++V ++
Sbjct: 2538 GLRDLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKD 2597
Query: 100 DEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGSKPAADI 159
DEG+YT F + LTV G ++ V E C+ + P +
Sbjct: 2598 DEGKYT---FYAGENMTSGKLTVAGGAISKPLT--DQTVAESQEAVFECEV--ANPDSKG 2650
Query: 160 RWFKNDKEIKDVKYLK-EEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQV 218
W ++ K + ++ E D +++ +++T + DD I ++ +
Sbjct: 2651 EWLRDGKHLPLTNNIRSESDGHKRRLIIAAT------KLDD----IGEYTYKVATSKTSA 2700
Query: 219 AMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVV 278
++V + ++K + T E Q + T E P + V W K+G L ++ +
Sbjct: 2701 KLKVEAVKIKKTLKNLTVT----ETQDAVFTVELT-HPNVKGVQWIKNGVVLESNEKYAI 2755
Query: 279 S 279
S
Sbjct: 2756 S 2756
Score = 29.6 bits (65), Expect = 5.6
Identities = 27/115 (23%), Positives = 44/115 (38%), Gaps = 14/115 (12%)
Query: 226 HYTPSVKIIPS---------TPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRM 276
HY + I P T + G + L KG+P P+ + W+K L D +
Sbjct: 19682 HYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPK-ITWSKPNVNLRDRIGL 19740
Query: 277 VVSGRELNILF----LNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLLPTTI 327
+ + + +NK D G Y N+ G+ V+ V D P + T+
Sbjct: 19741 DIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTV 19795
Score = 29.3 bits (64), Expect = 7.4
Identities = 28/116 (24%), Positives = 49/116 (42%), Gaps = 15/116 (12%)
Query: 224 EIHYTPSVKIIPSTPFPQEGQPLILT----------CESKGKPLPEPVLWTKDGGELPDP 273
E +T +K +P F +E + +ILT E P W KDG + +
Sbjct: 11103 EAPFTYQLKAVP-LKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRES 11161
Query: 274 D--RMVVSG--RELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLLPT 325
R + G R+L+I+ + +D G Y C + ++ L+V ++P + T
Sbjct: 11162 PKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKT 11217
Score = 28.9 bits (63), Expect = 9.6
Identities = 77/334 (23%), Positives = 133/334 (39%), Gaps = 61/334 (18%)
Query: 52 DNTSLQWSNPAQQ-----TLYFDDKKALRDNRIELVRASWHELSISVSDVS-LSDEGQY- 104
++ +LQW P T Y +KK L + R ++AS+ + + +V+ L ++ +Y
Sbjct: 22453 NSVTLQWKKPTYDGGSKITGYIVEKKELPEGR--WMKASFTNIIDTHFEVTGLVEDHRYE 22510
Query: 105 -------TCSLFTMPVKTSKAYLTVLGVPEKPQIS-----GFSSPVMEGDLMQLTCKTSG 152
+F+ P +++ A +T + P+IS + V G+ ++ G
Sbjct: 22511 FRVIARNAAGVFSEPSESTGA-ITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYG 22569
Query: 153 SKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESL 212
KP I+W K D+E+ +N + ST DF S V RVD S
Sbjct: 22570 -KPIPTIQWIKGDQEL----------SNTARLEIKST-DFATSLS---VKDAVRVD--SG 22612
Query: 213 NATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLI--LTCESKGKPLPEPVLWTKDGG-- 268
N + E T +VK++ P P EG +I +T E P+ +DGG
Sbjct: 22613 NYILKAKNVAGERSVTVNVKVL-DRPGPPEGPVVISGVTAEKCTLAWKPPL---QDGGSD 22668
Query: 269 ------ELPDPDRMVVSGRELNILFLN-------KTDNGTYRCEATNTIGQSS-AEYVLI 314
E + R+V + + N+ L+ + + T+R A N G E +
Sbjct: 22669 IINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPV 22728
Query: 315 VHDVPNTLLPTTIIPSLTTATVTTTVAITTSPTT 348
V P + P +TT T + + + P +
Sbjct: 22729 VAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPAS 22762
>gi|157311649 neogenin homolog 1 [Homo sapiens]
Length = 1461
Score = 82.0 bits (201), Expect = 1e-15
Identities = 87/329 (26%), Positives = 137/329 (41%), Gaps = 38/329 (11%)
Query: 35 TVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISVS 94
+V G AIL C V+ + ++W Q L L D I+L + +S
Sbjct: 162 SVYAGNNAILNCEVNADLVPFVRWEQNRQPLL-------LDDRVIKLPSGM-----LVIS 209
Query: 95 DVSLSDEGQYTCSLFT--MPVKTSKAYLTVLGVPEKPQISGF---SSPVME--GDLMQLT 147
+ + D G Y C + + P + + L VL PE F SP++ G + L
Sbjct: 210 NATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLP 269
Query: 148 CKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRV 207
C SG P I+W KN++ L E + R +L+ DD C
Sbjct: 270 CVASGL-PTPTIKWMKNEEA------LDTESSERLVLLAGGSLEISDVTEDDAGTYFCIA 322
Query: 208 DH--ESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTK 265
D+ E++ A ++ +Q P P+ + E ++ CE GKP P V W K
Sbjct: 323 DNGNETIEAQAELTVQA-----QPEFLKQPTNIYAHESMDIVFECEVTGKPTPT-VKWVK 376
Query: 266 DGGE-LPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIG--QSSAEYVLIVHDVPNTL 322
+G +P +V L +L L K+D G Y+C A N +G Q+ A+ +++ H P T
Sbjct: 377 NGDMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEH-APATT 435
Query: 323 LPTTIIPSLTTATVTTTVAITTSPTTSAT 351
P P A++ +T I + T A+
Sbjct: 436 GPLPSAPRDVVASLVSTRFIKLTWRTPAS 464
Score = 32.3 bits (72), Expect = 0.87
Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 10/84 (11%)
Query: 227 YTPSVKII-PSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGEL---PDPDRMVVSGRE 282
+TP ++ P G +IL C + +P P+ + W KDG L D R ++
Sbjct: 50 FTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPK-IEWKKDGTFLNLVSDDRRQLLPDGS 108
Query: 283 LNILFL-----NKTDNGTYRCEAT 301
L I + NK D G Y+C AT
Sbjct: 109 LFISNVVHSKHNKPDEGYYQCVAT 132
>gi|5360210 poliovirus receptor related 2 isoform alpha precursor
[Homo sapiens]
Length = 479
Score = 81.6 bits (200), Expect = 1e-15
Identities = 67/240 (27%), Positives = 101/240 (42%), Gaps = 11/240 (4%)
Query: 84 ASWHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVM--EG 141
A + ++++ +++ DEG YTC T P K S +T L V KP+ + V +
Sbjct: 118 AELQDATLALHGLTVEDEGNYTCEFATFP-KGSVRGMTWLRVIAKPKNQAEAQKVTFSQD 176
Query: 142 DLMQLTCKTSGSKPAADIRWFKN-DKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDG 200
C + +P A I W + D E K+ + T TV+S DG
Sbjct: 177 PTTVALCISKEGRPPARISWLSSLDWEAKETQV---SGTLAGTVTVTSRFTLVPSGRADG 233
Query: 201 VAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQ-PLILTCESKGKPLPE 259
V V C+V+HES P + L + Y P V I G+ L+C+ + P P
Sbjct: 234 VTVTCKVEHESFE-EPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPT 292
Query: 260 PVLWTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
W+ G P V G +L I ++ N T+ C TN +G AE V+ V + P
Sbjct: 293 GYDWSTTSGTF--PTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETP 350
>gi|33519481 neural cell adhesion molecule 2 precursor [Homo
sapiens]
Length = 837
Score = 80.5 bits (197), Expect = 3e-15
Identities = 97/416 (23%), Positives = 171/416 (41%), Gaps = 53/416 (12%)
Query: 38 EGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDK-KALRDNRIELVRASWHELSISVSDV 96
+G A + CRV + ++ W LY +++ + DNR ++ + ++ + ++
Sbjct: 128 QGEDAEVVCRVSSSPAPAVSW-------LYHNEEVTTISDNRFAMLANN----NLQILNI 176
Query: 97 SLSDEGQYTCS--LFTMPVKTSKAYLTVLGVPEKPQIS----GFSSPVMEGDLMQLTCKT 150
+ SDEG Y C + + + ++ VP P IS F++ G+ M +C+
Sbjct: 177 NKSDEGIYRCEGRVEARGEIDFRDIIVIVNVP--PAISMPQKSFNATAERGEEMTFSCRA 234
Query: 151 SGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDR--SDDGVAVICRVD 208
SGS P I WF+N K I++ N K S + V + DG +CR
Sbjct: 235 SGS-PEPAISWFRNGKLIEE---------NEKYILKGSNTELTVRNIINSDGGPYVCRAT 284
Query: 209 HESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTK--D 266
+++ Q +QV P + + + + GQ + L C+++G+P+PE + W + D
Sbjct: 285 NKAGEDEKQAFLQVF---VQPHIIQLKNETTYENGQ-VTLVCDAEGEPIPE-ITWKRAVD 339
Query: 267 GGELPDPD-----RMVVSGRE----LNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHD 317
G + D R+ V G+ L+I + +D+G Y CEA + IG L +
Sbjct: 340 GFTFTEGDKSLDGRIEVKGQHGSSSLHIKDVKLSDSGRYDCEAASRIGGHQKSMYLDIEY 399
Query: 318 VPNTLLPTTIIPSLTTATVTTTVAITTSPTTSATTSSIRDPNALAGQNGPDHALIGGIVA 377
P + TI S + + + ++P S RD L +N +
Sbjct: 400 APKFISNQTIYYSWEGNPINISCDVKSNPPASIHWR--RDKLVLPAKNTTNLKTYSTGRK 457
Query: 378 VVVFVTLCSIFLLGRY---LARHKGTYLTNEAKGAEDAPDADTAIINAEGSQVNAE 430
+++ + S GRY H GT D P + + E SQ A+
Sbjct: 458 MILEIAPTSDNDFGRYNCTATNHIGTRFQEYILALADVPSSPYGVKIIELSQTTAK 513
Score = 72.4 bits (176), Expect = 8e-13
Identities = 86/325 (26%), Positives = 136/325 (41%), Gaps = 48/325 (14%)
Query: 33 NVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSIS 92
N T G +CR + ++ W F + K + +N +++ S EL+
Sbjct: 219 NATAERGEEMTFSCRASGSPEPAISW---------FRNGKLIEENEKYILKGSNTELT-- 267
Query: 93 VSDVSLSDEGQYTCSLFTMPVKTSK-AYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTS 151
V ++ SD G Y C + K A+L V P Q+ + E + L C
Sbjct: 268 VRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQPHIIQLK--NETTYENGQVTLVCDAE 325
Query: 152 GSKPAADIRWFK---------NDKEIKDVKYLKEEDANRKTFTVSSTLDFR-VDRSDDGV 201
G +P +I W + DK + +K + SS+L + V SD G
Sbjct: 326 G-EPIPEITWKRAVDGFTFTEGDKSLDGRIEVKGQHG-------SSSLHIKDVKLSDSG- 376
Query: 202 AVICRVDHESLNATP--QVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPE 259
R D E+ + Q +M L+I Y P + + EG P+ ++C+ K P P
Sbjct: 377 ----RYDCEAASRIGGHQKSMY-LDIEYAPKFISNQTIYYSWEGNPINISCDVKSNP-PA 430
Query: 260 PVLWTKDGGELPDPD----RMVVSGRELNILFLNKTDN--GTYRCEATNTIGQSSAEYVL 313
+ W +D LP + + +GR++ + +DN G Y C ATN IG EY+L
Sbjct: 431 SIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATNHIGTRFQEYIL 490
Query: 314 IVHDVPNTLLPTTIIP-SLTTATVT 337
+ DVP++ II S TTA V+
Sbjct: 491 ALADVPSSPYGVKIIELSQTTAKVS 515
Score = 48.1 bits (113), Expect = 2e-05
Identities = 51/211 (24%), Positives = 83/211 (39%), Gaps = 21/211 (9%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSI 91
+N T E G L C + + W + + K+L D RIE V+ S+
Sbjct: 308 KNETTYENGQVTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSL-DGRIE-VKGQHGSSSL 365
Query: 92 SVSDVSLSDEGQYTCSLFTMPVKTSKA-YLTVLGVPE--KPQISGFSSPVMEGDLMQLTC 148
+ DV LSD G+Y C + K+ YL + P+ Q +S EG+ + ++C
Sbjct: 366 HIKDVKLSDSGRYDCEAASRIGGHQKSMYLDIEYAPKFISNQTIYYS---WEGNPINISC 422
Query: 149 KTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVD 208
S P A I W + DK + K N KT++ + + + D D
Sbjct: 423 DVK-SNPPASIHW-RRDKLVLPAK----NTTNLKTYSTGRKMILEIAPTSDN-------D 469
Query: 209 HESLNATPQVAMQVLEIHYTPSVKIIPSTPF 239
N T + Y ++ +PS+P+
Sbjct: 470 FGRYNCTATNHIGTRFQEYILALADVPSSPY 500
Score = 45.1 bits (105), Expect = 1e-04
Identities = 43/185 (23%), Positives = 76/185 (41%), Gaps = 17/185 (9%)
Query: 141 GDLMQLTCKTSGSKPAADIRWF--KNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSD 198
G+ TC G + D W+ + +K I + + +++ R T+ + + D
Sbjct: 35 GESKFFTCTAIGEPESID--WYNPQGEKIISTQRVVVQKEGVRSRLTI-----YNANIED 87
Query: 199 DGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLP 258
G I R Q A VLEI+ + + + S ++G+ + C P P
Sbjct: 88 AG---IYRCQATDAKGQTQEATVVLEIYQKLTFREVVSPQEFKQGEDAEVVCRVSSSPAP 144
Query: 259 EPVLWTKDGGE---LPDPDRMVVSGRELNILFLNKTDNGTYRCEA-TNTIGQSSAEYVLI 314
V W E + D +++ L IL +NK+D G YRCE G+ +++
Sbjct: 145 A-VSWLYHNEEVTTISDNRFAMLANNNLQILNINKSDEGIYRCEGRVEARGEIDFRDIIV 203
Query: 315 VHDVP 319
+ +VP
Sbjct: 204 IVNVP 208
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 80.1 bits (196), Expect = 4e-15
Identities = 88/328 (26%), Positives = 142/328 (43%), Gaps = 48/328 (14%)
Query: 33 NVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSIS 92
NVTV G TA+L+CRV +L W D + L + + + + +LS+
Sbjct: 408 NVTVSPGETAVLSCRVLGEAPYNLTWVR---------DWRVLPASTGRVAQLA--DLSLE 456
Query: 93 VSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSP--VMEGDLMQLTCKT 150
+S + +D G+Y C + + ++A + +L V E PQ+S +S +G ++++C
Sbjct: 457 ISGIIPTDGGRYQC-VASNANGVTRASVWLL-VREAPQVSIHTSSQHFSQGVEVKVSCSA 514
Query: 151 SGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHE 210
SG P I W + + +++ D R+ G +I V E
Sbjct: 515 SGY-PTPHISWSRESQALQE--------------------DSRIHVDAQGTLIIQGVAPE 553
Query: 211 -----SLNATPQVA--MQVLEIHYT--PSVKIIPSTPFPQEGQPLILTCESKGKPLPEPV 261
S AT +V + + ++YT PSV + + G+ +L CE+ G P P V
Sbjct: 554 DAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPR-V 612
Query: 262 LWTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPN- 320
+W + G E+ SG+ L I + D GTY C A N +G +SAE L V P
Sbjct: 613 IWYRGGLEMILAPEGSSSGK-LRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQL 671
Query: 321 TLLPTTIIPSLTTATVTTTVAITTSPTT 348
T LP + L + + A P T
Sbjct: 672 TELPRDVTVELGRSALLACRATGRPPPT 699
Score = 57.4 bits (137), Expect = 3e-08
Identities = 70/296 (23%), Positives = 110/296 (37%), Gaps = 25/296 (8%)
Query: 30 LTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHEL 89
L ++VTV G +A+L CR ++ W Q L LR R+ +
Sbjct: 674 LPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPL------GLRLGAGRGSRSRQPDS 727
Query: 90 SISVSD-VSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSP---VMEGDLMQ 145
+ + V+ D+ Y C + K ++ PQI+ S+P V+EG +
Sbjct: 728 GVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIAS-SAPTVRVLEGQPVS 786
Query: 146 LTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVIC 205
L C +P + W K+ + + +R + +L + C
Sbjct: 787 LPCIVLAGRPLPERHWLKDGRPLPP--------GSRHSIRADGSLHLDRALQEHAGRYSC 838
Query: 206 RVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTK 265
+ + + V L + P + + EG P L C + G P P + WTK
Sbjct: 839 VATNTAGSQHRDVE---LVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPT-ITWTK 894
Query: 266 DGGELPD--PDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
+ L P V L I + D G Y C ATNT+G SS E L V+ P
Sbjct: 895 ETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKP 950
Score = 52.8 bits (125), Expect = 6e-07
Identities = 59/238 (24%), Positives = 100/238 (42%), Gaps = 31/238 (13%)
Query: 90 SISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVME--GDLMQLT 147
++ + V+ D G Y+C T V T + +T L + P +S ++ V+ G+ L
Sbjct: 544 TLIIQGVAPEDAGNYSCQA-TNEVGTDQETVT-LYYTDPPSVSAVNAVVLVAVGEEAVLV 601
Query: 148 CKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRV 207
C+ SG P I W++ E+ L E ++ S L + D CR
Sbjct: 602 CEASGVPPPRVI-WYRGGLEM----ILAPEGSS------SGKLRIPAAQERDAGTYTCRA 650
Query: 208 DHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDG 267
+E +A+ ++ L + + P + +P + G+ +L C + G+P P V W +
Sbjct: 651 VNELGDASAEIQ---LAVGHAPQLTELPRDVTVELGRSALLACRATGRP-PPTVTWRRGD 706
Query: 268 GELPDPDRMVVSGR-------ELNILFLNKT---DNGTYRCEATNTIGQSSAEYVLIV 315
G+ + +GR + +LF D Y CEA N G+ AE LIV
Sbjct: 707 GQ--PLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIV 762
Score = 52.4 bits (124), Expect = 8e-07
Identities = 66/286 (23%), Positives = 102/286 (35%), Gaps = 26/286 (9%)
Query: 34 VTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISV 93
V V+EG L C V P + + D + L +RA S+ +
Sbjct: 777 VRVLEGQPVSLPCIVLAG--------RPLPERHWLKDGRPLPPGSRHSIRADG---SLHL 825
Query: 94 SDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGS 153
G+Y+C + V+ VP + + EG L C SG
Sbjct: 826 DRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGV 885
Query: 154 KPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLN 213
PA I W K + + TL + D A +C +
Sbjct: 886 -PAPTITWTKETNALTS-------RGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGF 937
Query: 214 ATPQVAMQVL---EIHYTPSVKI-IPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGE 269
++ ++ + V IH S +P + G+ + L CE+KG P P V WTKD
Sbjct: 938 SSQEMRLSVNTKPRIHMNGSRNANVPLQVTAKAGEEVTLDCEAKGSP-PPLVTWTKDSRP 996
Query: 270 LPDPDRM--VVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVL 313
+P ++ L + + D+G Y C A+N G +S YVL
Sbjct: 997 VPPITNRYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSASHRYVL 1042
Score = 38.5 bits (88), Expect = 0.012
Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 5/98 (5%)
Query: 244 QPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGREL-NILFLNKTDNGTYRCEATN 302
QPL+++C S LP + + L + SG IL +K + GTY C A +
Sbjct: 325 QPLLVSC-SVHSALPFRLQLRRGEARLGEERHFQESGNSSWEILRASKAEEGTYECTAVS 383
Query: 303 TIGQSSAEYVLIVHDVPNTLLPTTIIPSLTTATVTTTV 340
G A+ ++V D P L+P P++T + T V
Sbjct: 384 RAGTGRAKAQIVVTDPPPQLVPA---PNVTVSPGETAV 418
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 80.1 bits (196), Expect = 4e-15
Identities = 88/328 (26%), Positives = 142/328 (43%), Gaps = 48/328 (14%)
Query: 33 NVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSIS 92
NVTV G TA+L+CRV +L W D + L + + + + +LS+
Sbjct: 525 NVTVSPGETAVLSCRVLGEAPYNLTWVR---------DWRVLPASTGRVAQLA--DLSLE 573
Query: 93 VSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSP--VMEGDLMQLTCKT 150
+S + +D G+Y C + + ++A + +L V E PQ+S +S +G ++++C
Sbjct: 574 ISGIIPTDGGRYQC-VASNANGVTRASVWLL-VREAPQVSIHTSSQHFSQGVEVKVSCSA 631
Query: 151 SGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHE 210
SG P I W + + +++ D R+ G +I V E
Sbjct: 632 SGY-PTPHISWSRESQALQE--------------------DSRIHVDAQGTLIIQGVAPE 670
Query: 211 -----SLNATPQVA--MQVLEIHYT--PSVKIIPSTPFPQEGQPLILTCESKGKPLPEPV 261
S AT +V + + ++YT PSV + + G+ +L CE+ G P P V
Sbjct: 671 DAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPR-V 729
Query: 262 LWTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPN- 320
+W + G E+ SG+ L I + D GTY C A N +G +SAE L V P
Sbjct: 730 IWYRGGLEMILAPEGSSSGK-LRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQL 788
Query: 321 TLLPTTIIPSLTTATVTTTVAITTSPTT 348
T LP + L + + A P T
Sbjct: 789 TELPRDVTVELGRSALLACRATGRPPPT 816
Score = 73.2 bits (178), Expect = 4e-13
Identities = 58/237 (24%), Positives = 104/237 (43%), Gaps = 17/237 (7%)
Query: 91 ISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKT 150
+ + V L DEG YTC+ + ++ + + VP + + V+E + L C
Sbjct: 1850 LQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLA 1909
Query: 151 SGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHE 210
SG P D+ WFK + + + T +V + R++++ A R
Sbjct: 1910 SGVPPP-DVSWFKGHQPVSSWMGV--------TVSVDGRV-LRIEQAQLSDAGSYRCVAS 1959
Query: 211 SLNATPQVAMQVLEIHYTPSVKIIPSTPFPQ-EGQPLILTCESKGKPLPEPVLWTKDGGE 269
++ + ++ L ++ P + + PS P P P+ LTC + G P P ++W KDG
Sbjct: 1960 NVAGSTELRYG-LRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPT-LMWLKDGNP 2017
Query: 270 LPDPD----RMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTL 322
+ ++ GR L + +D+G Y C A + +G+ + VL VH P+ L
Sbjct: 2018 VSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSIL 2074
Score = 67.4 bits (163), Expect = 2e-11
Identities = 72/303 (23%), Positives = 124/303 (40%), Gaps = 29/303 (9%)
Query: 29 PLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHE 88
P T+ V+ V G +LTC V PA + D+ + + + V +
Sbjct: 3129 PKTETVSQVAGSPLVLTCDVS---------GVPAPTVTWLKDRMPVESSAVHGVVSRGGR 3179
Query: 89 LSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSP--VMEGDLMQL 146
L + S + + G YTC + K ++ + V + + SG + V+EG ++L
Sbjct: 3180 LQL--SRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRL 3237
Query: 147 TCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICR 206
C+ G +P D+ W K+ + ++ + + + +L + R+ D A C
Sbjct: 3238 DCEADG-QPPPDVAWLKDGSPLG-----QDMGPHLRFYLDGGSLVLKGLRASDAGAYTC- 3290
Query: 207 VDHESLNATPQVAMQVLEIHYTPSVK---IIPSTPFPQEGQPLILTCESKGKPLPEPVLW 263
V H A + + + P++K T + G+ + + C +G P P V W
Sbjct: 3291 VAHNP--AGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSP-PIHVSW 3347
Query: 264 TKDGGELPDPDRMVV--SGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNT 321
KDG LP R ++ SG L I + D G + C A + G + + L V VP
Sbjct: 3348 LKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQV-QVPPV 3406
Query: 322 LLP 324
L P
Sbjct: 3407 LEP 3409
Score = 65.5 bits (158), Expect = 9e-11
Identities = 64/247 (25%), Positives = 101/247 (40%), Gaps = 33/247 (13%)
Query: 91 ISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISG--FSSPVMEGDLMQLTC 148
++++ SD G+Y+C + + + VL V P I G + V+ + + L C
Sbjct: 2035 LTLASARASDSGRYSCVAVSAVGEDRQD--VVLQVHMPPSILGEELNVSVVANESVALEC 2092
Query: 149 KTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVD 208
++ P + W+K+ + + E + L +VDR+D +
Sbjct: 2093 QSHAMPPPV-LSWWKDGRPL--------EPRPGVHLSADKAL-LQVDRAD-----VWDAG 2137
Query: 209 HESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQ-------EGQPLILTCESKGKPLPEPV 261
H + A Q E HY +V + P P + EG P L+CE +G P P+ +
Sbjct: 2138 HYTCEALNQAGHS--EKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFPK-I 2194
Query: 262 LWTKDGGELPDP----DRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHD 317
W KDG LP + GR L + GTY CE +N +G SS + L VH
Sbjct: 2195 SWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHV 2254
Query: 318 VPNTLLP 324
P P
Sbjct: 2255 PPQIAGP 2261
Score = 63.9 bits (154), Expect = 3e-10
Identities = 70/296 (23%), Positives = 117/296 (39%), Gaps = 32/296 (10%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSI 91
+ VT + + L C V + N + W + D +AL + H L +
Sbjct: 2945 EQVTAILNSSVSLPCDVHAHPNPEVTW---------YKDSQALSLGEEVFLLPGTHTLQL 2995
Query: 92 SVSDVSLSDEGQYTCSLFTMPVKTSK-AYLTVLGVP---EKPQISGFSSPVMEGDLMQLT 147
+ LSD G YTC + K L+VL P + P+ + V GD L+
Sbjct: 2996 GRA--RLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLS 3053
Query: 148 CKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRV 207
C+T + P + W+K+ + + + + ++ L+ + + D C+V
Sbjct: 3054 CETD-ALPEPTVTWYKDGQPLVLAQRTQALRGGQR-------LEIQEAQVSDKGLYSCKV 3105
Query: 208 DHESLNA--TPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTK 265
+ + A T + +QV P + + G PL+LTC+ G P P V W K
Sbjct: 3106 SNVAGEAVRTFTLTVQVPPTFENPKTETVSQVA----GSPLVLTCDVSGVPAPT-VTWLK 3160
Query: 266 DGGELPDP--DRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
D + +V G L + L GTY C A NT ++ ++V+ V P
Sbjct: 3161 DRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAP 3216
Score = 62.0 bits (149), Expect = 1e-09
Identities = 62/271 (22%), Positives = 109/271 (40%), Gaps = 30/271 (11%)
Query: 62 AQQTLYFDDKKA-LRDNRIELVRASWHEL------SISVSDVSLSDEGQYTCSLFTMPVK 114
A T+ F ++ L NR+ L + W E S+ ++ V + D G Y C+
Sbjct: 1048 ATNTVGFSSQEMRLSVNRLALSKYVWEEYGLLPSGSLRLAQVQVGDSGHYECTASNPAGS 1107
Query: 115 TSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYL 174
S Y+ + VP + Q V+ G+ + L C G+ P + W K+ ++
Sbjct: 1108 ASHRYVLGVQVPPQVQPGPRVLKVLVGEALDLNCVAEGN-PEPQLSWSKDGVVLQGRG-- 1164
Query: 175 KEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKII 234
++ F R+ D C + + +V ++VLE P
Sbjct: 1165 -----------PQGSVHFAAIRTSDAGRYRCEASNSAGVDAWEVELRVLE---PPHWGAD 1210
Query: 235 PSTPFPQE--GQPLILTCESKGKPLPEPVLWTKDGGELP---DPDRMVVSGRELNILFLN 289
++ + G+ L C ++G P P+ V W K P P V+ L + ++
Sbjct: 1211 ETSGLLERVAGENASLPCPARGTPKPQ-VTWRKGPSSEPLHGQPGVAVLEEGSLFLASVS 1269
Query: 290 KTDNGTYRCEATNTIGQSSAEYVLIVHDVPN 320
D+G Y C+ATN +G +S L+V+ P+
Sbjct: 1270 PADSGDYECQATNEVGSTSRRAKLVVYVPPS 1300
Score = 60.1 bits (144), Expect = 4e-09
Identities = 73/277 (26%), Positives = 111/277 (40%), Gaps = 19/277 (6%)
Query: 100 DEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVME--GDLMQLTCKTSGSKPAA 157
D G YTC S +G PQ++ V G L C+ +G +P
Sbjct: 759 DAGTYTCRAVNELGDASAEIQLAVG--HAPQLTELPRDVTVELGRSALLACRATG-RPPP 815
Query: 158 DIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQ 217
+ W + D + ++ L +R S L F +D +C E+ N +
Sbjct: 816 TVTWRRGDGQPLGLR-LGAGRGSRSRQPDSGVLFFESVAPEDQAPYVC----EARNVFGK 870
Query: 218 V---AMQVLEIHYTPSVKIIPSTPFPQEGQPLILTC-ESKGKPLPEPVLWTKDGGELPDP 273
V A ++ H P + T EGQP+ L C G+PLPE W KDG LP
Sbjct: 871 VQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERH-WLKDGRPLPPG 929
Query: 274 DRMVV-SGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLLPTTIIPSLT 332
R + + L++ + G Y C ATNT G + L+V VP + PT +T
Sbjct: 930 SRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVV-QVPPRIHPTA-THHIT 987
Query: 333 TATVTTTVAITTSPTTSATTSSIRDPNALAGQNGPDH 369
V ++ S + T + ++ NAL + GP +
Sbjct: 988 NEGVPASLPCVASGVPAPTITWTKETNALTSR-GPHY 1023
Score = 59.3 bits (142), Expect = 7e-09
Identities = 83/347 (23%), Positives = 132/347 (38%), Gaps = 51/347 (14%)
Query: 30 LTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDK---KALRDNRIELVRASW 86
L + VTV T L C N ++ W Q L F + L D ++
Sbjct: 2851 LVEEVTVNASSTVSLQCPALGNPVPTISW---LQNGLPFSPSPRLQVLEDGQV------- 2900
Query: 87 HELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDL--- 143
+ VS ++D Y C K + + VP P+I+G + L
Sbjct: 2901 ----LQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVP--PRIAGLDLEQVTAILNSS 2954
Query: 144 MQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDR---SDDG 200
+ L C + P ++ W+K+ + + L EE F + T ++ R SD G
Sbjct: 2955 VSLPCDVH-AHPNPEVTWYKDSQALS----LGEE-----VFLLPGTHTLQLGRARLSDSG 3004
Query: 201 VAVICRVDHESLNATPQVAMQV-LEIHYTPSVKIIPSTP----FPQEGQPLILTCESKGK 255
+ E+LNA + V L + P+ + P P + G +L+CE+
Sbjct: 3005 MYTC-----EALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDA- 3058
Query: 256 PLPEP-VLWTKDGGELPDPDRMVV--SGRELNILFLNKTDNGTYRCEATNTIGQSSAEYV 312
LPEP V W KDG L R G+ L I +D G Y C+ +N G++ +
Sbjct: 3059 -LPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFT 3117
Query: 313 LIVHDVPNTLLP-TTIIPSLTTATVTTTVAITTSPTTSATTSSIRDP 358
L V P P T + + + + T ++ P + T R P
Sbjct: 3118 LTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMP 3164
Score = 59.3 bits (142), Expect = 7e-09
Identities = 63/293 (21%), Positives = 113/293 (38%), Gaps = 35/293 (11%)
Query: 33 NVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSIS 92
+++ EG A L C+ + ++ W Q + K ++ + +
Sbjct: 4046 DLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSG-----------ELL 4094
Query: 93 VSDVSLSDEGQYTCSLFTMPVKT-SKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTS 151
V ++ D G YTC+ + + +LT+L +P + G S + GD + L C
Sbjct: 4095 VKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRS-LRLGDRLWLRCAAR 4153
Query: 152 GSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHES 211
GS P I W ND+ + + + E+D STL +D +C ++
Sbjct: 4154 GS-PTPRIGWTVNDRPV--TEGVSEQDG-------GSTLQRAAVSREDSGTYVCWAENRV 4203
Query: 212 LNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQP----LILTCESKGKPLPEPVLWTKDG 267
Q + + ++ F +P + L C +G P+P+ + W KDG
Sbjct: 4204 GRT------QAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPD-IHWIKDG 4256
Query: 268 GELPDPD-RMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
L R + L I + D G Y+C A N +G + +L++ P
Sbjct: 4257 LPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAP 4309
Score = 57.8 bits (138), Expect = 2e-08
Identities = 71/276 (25%), Positives = 115/276 (41%), Gaps = 23/276 (8%)
Query: 96 VSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFS-SPVME--GDLMQLTCKTSG 152
VS D G Y C +T ++ + V E P + G + S ++E G +QL C G
Sbjct: 4187 VSREDSGTYVCWAENRVGRTQA--VSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRG 4244
Query: 153 SKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESL 212
P DI W K+ ++ +L+ + N S R +R D G C ++E +
Sbjct: 4245 D-PVPDIHWIKDGLPLRG-SHLRHQLQN------GSLTIHRTERDDAG-RYQCLAENE-M 4294
Query: 213 NATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPD 272
+V + VL+ P ++ P + G + L C++ G+P P + W + G L
Sbjct: 4295 GVAKKVVILVLQS--APVFQVEPQDMTVRSGDDVALRCQATGEPTPT-IEWLQAGQPLRA 4351
Query: 273 PDRM-VVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP----NTLLPTTI 327
R+ + L + + D GTY C A N +G ++A L+V P ++
Sbjct: 4352 SRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQGSWGSMTGVIN 4411
Query: 328 IPSLTTATVTTTVAITTSPTTSATTSSIRDPNALAG 363
AT+ T+V S+ SSIR A G
Sbjct: 4412 GRKFGVATLNTSVMQEAHSGVSSIHSSIRHVPANVG 4447
Score = 56.6 bits (135), Expect = 4e-08
Identities = 57/252 (22%), Positives = 111/252 (44%), Gaps = 24/252 (9%)
Query: 91 ISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSP----VMEGDLMQL 146
+ ++ + DEG+Y C F+ + ++ + + P P I G + VME L+QL
Sbjct: 1465 LRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAP--PTIWGSNETGEVAVMEDHLVQL 1522
Query: 147 TCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICR 206
C+ G P +I WFK+ + + R+ L +S D C+
Sbjct: 1523 LCEARGV-PTPNITWFKDGALLPTSTKVVYTRGGRQ-------LQLGRAQSSDAGVYTCK 1574
Query: 207 VDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQE---GQPLILTCESKGKPLPEPVLW 263
+ ++ A + L+++ P+++ P+ + G+P+ L C ++G P P + W
Sbjct: 1575 ASN-AVGAAEKATR--LDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPT-LSW 1630
Query: 264 TKDGGELPDPD--RMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNT 321
+G + + + R+ G L + + +G Y C A++ G++ +Y + V VP
Sbjct: 1631 HHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEV-QVPPQ 1689
Query: 322 LLPTTIIPSLTT 333
LL + +TT
Sbjct: 1690 LLVAEGLGQVTT 1701
Score = 56.6 bits (135), Expect = 4e-08
Identities = 77/343 (22%), Positives = 129/343 (37%), Gaps = 46/343 (13%)
Query: 29 PLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIEL-VRASWH 87
P TQ V+VV+ G A L C ++ W Q EL ++
Sbjct: 2264 PPTQ-VSVVQDGVATLECNATGKPPPTVTWERDGQPV------------GAELGLQLQNQ 2310
Query: 88 ELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVME-----GD 142
S+ V + G+Y+C + + + + + VP P++ G P+
Sbjct: 2311 GQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVP--PELIGDLDPLTNITAALHS 2368
Query: 143 LMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSS--TLDFRVDRSDDG 200
+ L C+ G P A IRWF+ ++ + T+ ++ L + D
Sbjct: 2369 PLTLLCEAMGIPPPA-IRWFRGEEPVSP---------GEDTYLLAGGWMLKMTQTQEQDS 2418
Query: 201 VAVICRVDHESLNATPQVAMQVLEIHYTPSVKI--IPSTPFPQEGQPLILTCESKGKPLP 258
C +E+ A +++VL PS++ + +GQ L C G P P
Sbjct: 2419 GLYSCLASNEAGEARRNFSVEVL---VPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQP 2475
Query: 259 EPVLWTKDGGELPDPDRMVVS--GRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVH 316
+ + W KDG L D +S G L +L N + G Y C A N +G+ + + L V
Sbjct: 2476 K-LTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSV- 2533
Query: 317 DVPNTLLPTTIIPSLTTATVTTTVAITTSPTTSATTSSIRDPN 359
L PT + + +A TV + + + PN
Sbjct: 2534 ----LLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPN 2572
Score = 56.6 bits (135), Expect = 4e-08
Identities = 75/311 (24%), Positives = 115/311 (36%), Gaps = 51/311 (16%)
Query: 30 LTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHEL 89
L + + V++G TA L C V + L W +D R L R H +
Sbjct: 2451 LEEVIKVLDGQTAHLMCNVTGHPQPKLTW---------------FKDGR-PLARGDAHHI 2494
Query: 90 S-----ISVSDVSLSDEGQYTC-SLFTMPVKTSKAYLTVLGVPE----KPQISGFSSPVM 139
S + V +LS G Y+C + + KT L+VL P + V
Sbjct: 2495 SPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVT 2554
Query: 140 EGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDD 199
+ + L C+ P+ +I W K+ E N + + L + +D
Sbjct: 2555 VNNPISLICEALAF-PSPNITWMKDGAPF-------EASRNIQLLPGTHGLQILNAQKED 2606
Query: 200 GVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEG---------QPLILTC 250
C V +E A ++VL PS+ P + G L L C
Sbjct: 2607 AGQYTCVVTNELGEAVKNYHVEVL---IPPSIS--KDDPLGEVGVKEVKTKVNSTLTLEC 2661
Query: 251 ESKGKPLPEPVLWTKDGGELPDPDRMVV--SGRELNILFLNKTDNGTYRCEATNTIGQSS 308
ES P P + W KDG + R+ V GR L I +D+G Y C ATN G+
Sbjct: 2662 ESWAVP-PPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDD 2720
Query: 309 AEYVLIVHDVP 319
++ +++ P
Sbjct: 2721 QDFNVLIQVPP 2731
Score = 55.8 bits (133), Expect = 7e-08
Identities = 69/293 (23%), Positives = 109/293 (37%), Gaps = 25/293 (8%)
Query: 30 LTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHEL 89
L ++VTV G +A+L CR ++ W Q L LR R+ +
Sbjct: 791 LPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPL------GLRLGAGRGSRSRQPDS 844
Query: 90 SISVSD-VSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSP---VMEGDLMQ 145
+ + V+ D+ Y C + K ++ PQI+ S+P V+EG +
Sbjct: 845 GVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIAS-SAPTVRVLEGQPVS 903
Query: 146 LTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVIC 205
L C +P + W K+ + + +R + +L + C
Sbjct: 904 LPCIVLAGRPLPERHWLKDGRPLPP--------GSRHSIRADGSLHLDRALQEHAGRYSC 955
Query: 206 RVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTK 265
+ + + V L + P + + EG P L C + G P P + WTK
Sbjct: 956 VATNTAGSQHRDVE---LVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPT-ITWTK 1011
Query: 266 DGGELPD--PDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVH 316
+ L P V L I + D G Y C ATNT+G SS E L V+
Sbjct: 1012 ETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVN 1064
Score = 54.3 bits (129), Expect = 2e-07
Identities = 53/180 (29%), Positives = 81/180 (45%), Gaps = 14/180 (7%)
Query: 193 RVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCES 252
+VD D+G+ C + + + +VA++VL P+++ P E + L C +
Sbjct: 1854 KVDLRDEGIYT-CAATNLAGESKREVALKVL---VPPNIEPGPVNKAVLENASVTLECLA 1909
Query: 253 KGKPLPEPVLWTKDGGELPDPDRMVVS----GRELNILFLNKTDNGTYRCEATNTIGQSS 308
G P P+ V W K G P M V+ GR L I +D G+YRC A+N G +
Sbjct: 1910 SGVPPPD-VSWFK--GHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTE 1966
Query: 309 AEYVLIVHDVPNTLLPTTII-PSLTTATVTTTVAITTSPTTSATTSSIRDPNALAGQNGP 367
Y L V+ P LP ++ P L V T T +P S T ++D N ++ P
Sbjct: 1967 LRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAP--SPTLMWLKDGNPVSPAGTP 2024
Score = 53.9 bits (128), Expect = 3e-07
Identities = 75/302 (24%), Positives = 119/302 (39%), Gaps = 38/302 (12%)
Query: 37 VEGGTAILTCRVDQNDNTSLQW-SNPAQQTLYFDDKKALRDNRIELVRASWHELSISVSD 95
V G A L C + W P+ + L+ A+ + E S+ ++
Sbjct: 1219 VAGENASLPCPARGTPKPQVTWRKGPSSEPLHGQPGVAVLE-----------EGSLFLAS 1267
Query: 96 VSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPV--MEGDLMQLTCKTSGS 153
VS +D G Y C TS+ V+ VP + G + V M G + L C +G
Sbjct: 1268 VSPADSGDYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGF 1327
Query: 154 KPAADIRWFKNDKEIK----------DVKYLKEEDANRKTFTVSSTLDF-RVDRSDDGVA 202
P +I W K+ + + D+ + + + +L F R+ D G+
Sbjct: 1328 -PVPEIVWLKDAQLVGVPLGWAGYGWDLGW--GQVGGHRLLDEGQSLHFPRIQEGDSGL- 1383
Query: 203 VICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTP--FPQEGQPLILTCESKGKPLPEP 260
CR ++++ A + VL PSV + G + L C + G P P+
Sbjct: 1384 YSCRAENQAGTAQRDFHLLVLT---PPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQ- 1439
Query: 261 VLWTKDGGE-LPDPDRMVVS--GRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHD 317
V WTKD LP + V G+ L I + D G Y+C A + GQ + ++ L VH
Sbjct: 1440 VEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHA 1499
Query: 318 VP 319
P
Sbjct: 1500 PP 1501
Score = 52.4 bits (124), Expect = 8e-07
Identities = 69/296 (23%), Positives = 115/296 (38%), Gaps = 40/296 (13%)
Query: 36 VVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISVSD 95
V+EG L C D P + D L + +R S+ +
Sbjct: 3229 VLEGQEVRLDCEAD---------GQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKG 3279
Query: 96 VSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPE--KPQISGFSSPVME-GDLMQLTCKTSG 152
+ SD G YTC + ++ + + VP K G + V G+L+ + C G
Sbjct: 3280 LRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRG 3339
Query: 153 SKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDR---SDDGVAVICRVDH 209
S P + W K+ + +++T S R+ + +D G+
Sbjct: 3340 SPPI-HVSWLKDGLPLP---------LSQRTLLHGSGHTLRISKVQLADAGIFTCVAASP 3389
Query: 210 ESL---NATPQVAMQ-VLE-IHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWT 264
+ N T QV + VLE + + V ++ G + L CE++G PLP V W
Sbjct: 3390 AGVADRNFTLQVQVPPVLEPVEFQNDVVVV-------RGSLVELPCEARGVPLPL-VSWM 3441
Query: 265 KDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPN 320
KDG L + + G L + + D+GTY C A + G++ + L V + P+
Sbjct: 3442 KDGEPLLS--QSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPH 3495
Score = 50.8 bits (120), Expect = 2e-06
Identities = 64/262 (24%), Positives = 107/262 (40%), Gaps = 24/262 (9%)
Query: 90 SISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVM--EGDLMQLT 147
S+ + D G Y+C + + ++ P +G + V+ G ++L
Sbjct: 1370 SLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADVELQ 1429
Query: 148 CKTSGSKPAADIRWFKNDKEI-KDVKYLK-EEDANRKTFTVSSTLDFRVDRSDDGVAVIC 205
C TSG P + W K+ + + +L+ +ED T S D+G
Sbjct: 1430 CWTSGV-PTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHV-------GDEG----- 1476
Query: 206 RVDHESLNATPQVAMQV-LEIHYTPSVKIIPSTP--FPQEGQPLILTCESKGKPLPEPVL 262
R + + Q A L +H P++ T E + L CE++G P P +
Sbjct: 1477 RYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPN-IT 1535
Query: 263 WTKDGGELPDPDRMVVS--GRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPN 320
W KDG LP ++V + GR+L + +D G Y C+A+N +G + L V+ VP
Sbjct: 1536 WFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVY-VPP 1594
Query: 321 TLLPTTIIPSLTTATVTTTVAI 342
T+ P + A VA+
Sbjct: 1595 TIEGAGGRPYVVKAVAGRPVAL 1616
Score = 50.4 bits (119), Expect = 3e-06
Identities = 51/229 (22%), Positives = 86/229 (37%), Gaps = 12/229 (5%)
Query: 91 ISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKT 150
+ ++ S D G Y C V+ VP + EG L CK
Sbjct: 4002 LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKA 4061
Query: 151 SGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHE 210
GS P +I W K+ + + + + T S L + D C ++
Sbjct: 4062 RGS-PEPNITWDKDGQPVSGAE-------GKFTIQPSGELLVKNLEGQDAGTYTCTAENA 4113
Query: 211 SLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGEL 270
A +V + +L + P +P + G L L C ++G P P + WT + +
Sbjct: 4114 VGRARRRVHLTILVL---PVFTTLPGDRSLRLGDRLWLRCAARGSPTPR-IGWTVNDRPV 4169
Query: 271 PDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
+ G L +++ D+GTY C A N +G++ A + V + P
Sbjct: 4170 TEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAP 4218
Score = 49.3 bits (116), Expect = 7e-06
Identities = 61/280 (21%), Positives = 110/280 (39%), Gaps = 39/280 (13%)
Query: 91 ISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKT 150
+ + + D GQYTC + + K Y + +P P IS P+ E + ++ K
Sbjct: 2597 LQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIP--PSISK-DDPLGEVGVKEVKTKV 2653
Query: 151 ---------SGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGV 201
S + P IRW+K+ + + L+ R L + + D
Sbjct: 2654 NSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGR-------LLQIQPTQVSDSG 2706
Query: 202 AVICRV------DHESLNATPQVAMQVLEI-HYTPSVKIIPS--------TPFPQ--EGQ 244
+C D + N QV ++ ++ + +I+ T + + E
Sbjct: 2707 RYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENN 2766
Query: 245 PLILTCESKGKPLPEPVLWTKDGGELPDPDRMVV--SGRELNILFLNKTDNGTYRCEATN 302
P L C++ P P+ + W ++ L D + V GR L I + + G Y C+A+N
Sbjct: 2767 PAYLYCDTNAIPPPD-LTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASN 2825
Query: 303 TIGQSSAEYVLIVHDVPNTLLPTTIIPSLTTATVTTTVAI 342
+G+ Y L+V P L T + T ++TV++
Sbjct: 2826 EVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSL 2865
Score = 48.9 bits (115), Expect = 9e-06
Identities = 59/247 (23%), Positives = 98/247 (39%), Gaps = 25/247 (10%)
Query: 81 LVRASWHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVM- 139
L+ S H L IS V L+D G +TC + + + + VP + F + V+
Sbjct: 3361 LLHGSGHTLRIS--KVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVV 3418
Query: 140 -EGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSD 198
G L++L C+ G P + W K+ + + ++ +L +
Sbjct: 3419 VRGSLVELPCEARGV-PLPLVSWMKDGEPLLS-----------QSLEQGPSLQLEAVGAG 3466
Query: 199 DGVAVICRVDHESLNATPQVAMQVLEI-HYTPSVKIIPSTPFPQEGQPLILTCESKGKPL 257
D C E+ A + V+E H S + P+ G P+ L C+++G P
Sbjct: 3467 DSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQ--PTELSLTPGAPMELLCDAQGTPQ 3524
Query: 258 PEPVLWTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHD 317
P + W KDG L R+ + R +L + D G Y C A + G + + V
Sbjct: 3525 PN-ITWHKDGQAL---TRLENNSRATRVLRVR--DAGLYTCLAESPAGAIEKSFRVRVQA 3578
Query: 318 VPNTLLP 324
PN + P
Sbjct: 3579 PPNIVGP 3585
Score = 48.5 bits (114), Expect = 1e-05
Identities = 72/326 (22%), Positives = 119/326 (36%), Gaps = 36/326 (11%)
Query: 91 ISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKT 150
+ + +S +D G Y+C+ TS A+ + + + V L C+
Sbjct: 3637 LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQA 3696
Query: 151 SGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHE 210
G PA + W K D+ D + + E + + L + D +C +
Sbjct: 3697 DGV-PAPLVSWRK-DRVPLDPRSPRFEILPEGSLRIQPVL------AQDAGHYLCLASNS 3748
Query: 211 SLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGE- 269
+ + ++VLE P++ PS P +L CE+ G P P V+W KDG +
Sbjct: 3749 AGSDRQGRDLRVLE---PPAIAPSPSNLTLTAHTPALLPCEASGSPKP-LVVWWKDGQKL 3804
Query: 270 ---LPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLLPTT 326
L ++ L + D+ + C +N +G++ Y + VH +P T
Sbjct: 3805 DFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVH------VPPT 3858
Query: 327 IIPSLTTATVT--TTVAITTSPT-TSATTSSIRDPNALAGQNGPDHALIGGIVAVVVFVT 383
I T TVT V +T T A T S A G G + V+
Sbjct: 3859 IADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYR-----------VS 3907
Query: 384 LCSIFLLGRYLARHKGTYLTNEAKGA 409
+G+ L H G Y + A
Sbjct: 3908 PSGALEIGQALPIHAGRYTCSARNSA 3933
Score = 47.4 bits (111), Expect = 3e-05
Identities = 59/292 (20%), Positives = 106/292 (36%), Gaps = 22/292 (7%)
Query: 29 PLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHE 88
P N+T+ A+L C + + W Q+ + L+ L+ ++
Sbjct: 3768 PSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDF-----RLQQGAYRLLPSN--- 3819
Query: 89 LSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTC 148
++ ++ D Q+ C + + + Y + VP V + LTC
Sbjct: 3820 -ALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTC 3878
Query: 149 KTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVD 208
++G PA + W K ++ + + + L R V
Sbjct: 3879 HSTGI-PAPTVSWSKAGAQL-GARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVA 3936
Query: 209 HESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGG 268
H+ + T Q + P VK +PS + ++L CE+ G P P + W K+G
Sbjct: 3937 HKHVFLTVQAS---------PVVKPLPSVVRAVAEEEVLLPCEASGIPRPT-ITWQKEGL 3986
Query: 269 ELPDP-DRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
+ V+ G +L I + D G Y C A N+ G + + L+V P
Sbjct: 3987 NVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPP 4038
Score = 46.2 bits (108), Expect = 6e-05
Identities = 61/230 (26%), Positives = 89/230 (38%), Gaps = 29/230 (12%)
Query: 99 SDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISG-----FSSPVMEGDLMQLTCKTSGS 153
SD G YTC KA T L V P I G + + G + L C G
Sbjct: 1566 SDAGVYTCKASNAVGAAEKA--TRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGH 1623
Query: 154 KPAADIRWFKNDKEIKDVKYLK-EEDAN----RKTFTVSSTLDFRVDRSDDGVAVICRVD 208
P+ + W + + + E D + SS L V S G AV+
Sbjct: 1624 -PSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVL---- 1678
Query: 209 HESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGG 268
+ QV Q+L V I GQPL L C++ G P+P + W ++G
Sbjct: 1679 --QYSVEVQVPPQLLVAEGLGQVTTIV-------GQPLELPCQASGSPVPT-IQWLQNGR 1728
Query: 269 ELPDPDRMVVS--GRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVH 316
+ + V+ G L+I + +G + C+ATN G + AE + VH
Sbjct: 1729 PAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVH 1778
Score = 45.4 bits (106), Expect = 1e-04
Identities = 75/346 (21%), Positives = 127/346 (36%), Gaps = 64/346 (18%)
Query: 7 CNLSLVPAAASKNKVKGSQGQ---FPLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQ 63
C S +AS V G Q P + + V+ G L C + N L WS
Sbjct: 1099 CTASNPAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEALDLNCVAEGNPEPQLSWSKDGV 1158
Query: 64 QTLYFDDKKALRDNRIELVRASWHELSISVSDVSLSDEGQYTCSLFTMP-VKTSKAYLTV 122
+++ + S+ + + SD G+Y C V + L V
Sbjct: 1159 -----------------VLQGRGPQGSVHFAAIRTSDAGRYRCEASNSAGVDAWEVELRV 1201
Query: 123 LGVPE--KPQISGFSSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIK-----DVKYLK 175
L P + SG V G+ L C G+ P + W K V L+
Sbjct: 1202 LEPPHWGADETSGLLERVA-GENASLPCPARGT-PKPQVTWRKGPSSEPLHGQPGVAVLE 1259
Query: 176 EEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKII- 234
E + + + + D+ C+ +E + +T + A V ++ PS++
Sbjct: 1260 EGSLFLASVSPADSGDYE-----------CQATNE-VGSTSRRAKLV--VYVPPSIREDG 1305
Query: 235 -PSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDP-----------------DRM 276
+ GQ L L C++ G P+PE ++W KD + P R+
Sbjct: 1306 RKANVSGMAGQSLTLECDANGFPVPE-IVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRL 1364
Query: 277 VVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTL 322
+ G+ L+ + + D+G Y C A N G + ++ L+V P+ L
Sbjct: 1365 LDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVL 1410
Score = 44.7 bits (104), Expect = 2e-04
Identities = 63/245 (25%), Positives = 96/245 (39%), Gaps = 28/245 (11%)
Query: 100 DEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSP-----VMEGDLMQLTCKTSGSK 154
D G YTC + K++ + P P I G P + G L+ L C ++
Sbjct: 3553 DAGLYTCLAESPAGAIEKSFRVRVQAP--PNIVGPRGPRFVVGLAPGQLV-LECSVE-AE 3608
Query: 155 PAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLNA 214
PA I W ++ + +EDA+ + L + + D C + +
Sbjct: 3609 PAPKITWHRDG-------IVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAA--G 3659
Query: 215 TPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELP--D 272
+ VA +V EIH P+++ P Q +L C++ G P P V W KD L
Sbjct: 3660 STSVAFRV-EIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAP-LVSWRKDRVPLDPRS 3717
Query: 273 PDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLLPTTIIPSLT 332
P ++ L I + D G Y C A+N+ G L V L P I PS +
Sbjct: 3718 PRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRV------LEPPAIAPSPS 3771
Query: 333 TATVT 337
T+T
Sbjct: 3772 NLTLT 3776
Score = 42.0 bits (97), Expect = 0.001
Identities = 67/369 (18%), Positives = 129/369 (34%), Gaps = 56/369 (15%)
Query: 11 LVPAAASKNKVKGSQGQFPLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDD 70
L+P + SK+ G G + V T L C +++W Q
Sbjct: 2630 LIPPSISKDDPLGEVG----VKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSR 2685
Query: 71 KKALRDNRIELVRASWHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQ 130
+ L + R+ + + +SD G+Y C + + + + ++ VP Q
Sbjct: 2686 LQVLGEGRL-----------LQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQ 2734
Query: 131 -ISGFSS-------------------PVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKD 170
+ FS+ ++E + L C T+ + P D+ W++ D+ +
Sbjct: 2735 KVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTN-AIPPPDLTWYREDQPLSA 2793
Query: 171 VKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPS 230
+ R L + R+++ C+ +E + VL TP
Sbjct: 2794 GDEVSVLQGGR-------VLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVL----TPP 2842
Query: 231 VKIIPSTPFPQE-----GQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVV--SGREL 283
V + + +E + L C + G P+P + W ++G R+ V G+ L
Sbjct: 2843 VILGDTEELVEEVTVNASSTVSLQCPALGNPVP-TISWLQNGLPFSPSPRLQVLEDGQVL 2901
Query: 284 NILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTL-LPTTIIPSLTTATVTTTVAI 342
+ D +Y C A N G + + L V P L + ++ ++V+ +
Sbjct: 2902 QVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDV 2961
Query: 343 TTSPTTSAT 351
P T
Sbjct: 2962 HAHPNPEVT 2970
Score = 38.5 bits (88), Expect = 0.012
Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 5/98 (5%)
Query: 244 QPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGREL-NILFLNKTDNGTYRCEATN 302
QPL+++C S LP + + L + SG IL +K + GTY C A +
Sbjct: 442 QPLLVSC-SVHSALPFRLQLRRGEARLGEERHFQESGNSSWEILRASKAEEGTYECTAVS 500
Query: 303 TIGQSSAEYVLIVHDVPNTLLPTTIIPSLTTATVTTTV 340
G A+ ++V D P L+P P++T + T V
Sbjct: 501 RAGTGRAKAQIVVTDPPPQLVPA---PNVTVSPGETAV 535
Score = 29.3 bits (64), Expect = 7.4
Identities = 30/140 (21%), Positives = 52/140 (37%), Gaps = 19/140 (13%)
Query: 39 GGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHEL---SISVSD 95
GG+ L C V + + W D LR + + H+L S+++
Sbjct: 4233 GGSIQLDCVVRGDPVPDIHW---------IKDGLPLRGSHLR------HQLQNGSLTIHR 4277
Query: 96 VSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGSKP 155
D G+Y C K + VL Q+ V GD + L C+ +G +P
Sbjct: 4278 TERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATG-EP 4336
Query: 156 AADIRWFKNDKEIKDVKYLK 175
I W + + ++ + L+
Sbjct: 4337 TPTIEWLQAGQPLRASRRLR 4356
Score = 28.9 bits (63), Expect = 9.6
Identities = 22/97 (22%), Positives = 37/97 (38%), Gaps = 13/97 (13%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSI 91
Q++TV G L C+ +++W Q + L D S+
Sbjct: 4316 QDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG------------SL 4363
Query: 92 SVSDVSLSDEGQYTCSLFT-MPVKTSKAYLTVLGVPE 127
+ +V D G Y C + T++A+L V G P+
Sbjct: 4364 WLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQ 4400
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 79.7 bits (195), Expect = 5e-15
Identities = 78/303 (25%), Positives = 122/303 (40%), Gaps = 38/303 (12%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKK---ALRDNRIELVRASWHE 88
QNV+V+ L C+ D +L W L KK ++ +NR L
Sbjct: 2111 QNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLL----KKPGLSISENRSVL------- 2159
Query: 89 LSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSS----PVMEGDLM 144
+ D + D G+YTC + KT K Y + VP P I G V+EG+L+
Sbjct: 2160 ---KIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVP--PNIGGSDELTQLTVIEGNLI 2214
Query: 145 QLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVI 204
L C++SG P ++ W K + L + + + L + D
Sbjct: 2215 SLLCESSGIPPP-NLIWKKKGSPV-----LTDSMGRVRILSGGRQLQISIAEKSDAALYS 2268
Query: 205 CRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTP---FPQEGQPLILTCESKGKPLPEPV 261
C + + A + +QV + P++ S P G+ + L CE +G P P V
Sbjct: 2269 CVASNVAGTAKKEYNLQV---YIRPTITNSGSHPTEIIVTRGKSISLECEVQGIP-PPTV 2324
Query: 262 LWTKDGGELPDPDRMVV--SGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
W KDG L + + G L + ++ +D G Y C A N G + +Y L VH P
Sbjct: 2325 TWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPP 2384
Query: 320 NTL 322
+ +
Sbjct: 2385 SII 2387
Score = 79.0 bits (193), Expect = 8e-15
Identities = 83/343 (24%), Positives = 140/343 (40%), Gaps = 42/343 (12%)
Query: 21 VKGSQGQFPLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIE 80
+KG+ P + VTV+ +A++ C + W Q L D K L + RI
Sbjct: 2871 IKGANSDLP--EEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRI- 2927
Query: 81 LVRASWHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSS---P 137
+ + + ++D G+Y C + ++K Y L V P + G S
Sbjct: 2928 ----------LQILNTQITDIGRYVC-VAENTAGSAKKYFN-LNVHVPPSVIGPKSENLT 2975
Query: 138 VMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRS 197
V+ + + LTC+ SG P D+ W KN++ IK N T V ++ R+
Sbjct: 2976 VVVNNFISLTCEVSGF-PPPDLSWLKNEQPIK---------LNTNTLIVPGGRTLQIIRA 3025
Query: 198 --DDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFP----QEGQPLILTCE 251
DG C +++ + + + L ++ PS+K S +EG + L CE
Sbjct: 3026 KVSDGGEYTCIAINQAGESKKKFS---LTVYVPPSIKDHDSESLSVVNVREGTSVSLECE 3082
Query: 252 SKGKPLPEPVLWTKDGGELPDPD--RMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSA 309
S P P + W K+G + + ++ G+ L+I +D G Y C A N G+
Sbjct: 3083 SNAVP-PPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDK 3141
Query: 310 EYVLIVHDVPNTLLP--TTIIPSLTTATVTTTVAITTSPTTSA 350
+ L V+ P+ P I+ +++ T A P T A
Sbjct: 3142 NFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIA 3184
Score = 72.0 bits (175), Expect = 1e-12
Identities = 87/359 (24%), Positives = 145/359 (40%), Gaps = 41/359 (11%)
Query: 31 TQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELS 90
T+ +TV++G + + C D S+ W Q L D + S H +
Sbjct: 3442 TEEITVLKGSSTSMACITDGTPAPSMAWLRDGQP-LGLDAH----------LTVSTHGMV 3490
Query: 91 ISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSS----PVMEGDLMQL 146
+ + D G+YTC + SK + +L V E P I+G V+ + ++L
Sbjct: 3491 LQLLKAETEDSGKYTCIASNEAGEVSKHF--ILKVLEPPHINGSEEHEEISVIVNNPLEL 3548
Query: 147 TCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICR 206
TC SG PA + W K+ + + ++ T L + +D C
Sbjct: 3549 TCIASGI-PAPKMTWMKDGRPLPQTDQVQ-------TLGGGEVLRISTAQVEDTGRYTCL 3600
Query: 207 VDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLI---LTCESKGKPLPEPVL- 262
S A ++ +H P+ I T P++ L +T E K +P PV+
Sbjct: 3601 A---SSPAGDDDKEYLVRVHVPPN---IAGTDEPRDITVLRNRQVTLECKSDAVPPPVIT 3654
Query: 263 WTKDGGELPDPDRMVV--SGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPN 320
W ++G L R+ + GR L I + D Y C A+N G+++ E++L V+ PN
Sbjct: 3655 WLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPN 3714
Query: 321 TL-LPTTIIPSLTTATVTTTVAITTSPTTSATTSSIRDPNALAGQNGPDHALIGGIVAV 378
P +++ L +TV +A PT T +D LAG + L G + +
Sbjct: 3715 IKGGPQSLVILLNKSTVLECIA-EGVPTPRITWR--KDGAVLAGNHARYSILENGFLHI 3770
Score = 69.3 bits (168), Expect = 6e-12
Identities = 74/309 (23%), Positives = 120/309 (38%), Gaps = 48/309 (15%)
Query: 29 PLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHE 88
P ++N+TVV LTC V L W +++ ++ N L+
Sbjct: 2969 PKSENLTVVVNNFISLTCEVSGFPPPDLSW---------LKNEQPIKLNTNTLIVPGGRT 3019
Query: 89 LSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSP------VMEGD 142
L I + VS D G+YTC ++ K + + VP P I S V EG
Sbjct: 3020 LQIIRAKVS--DGGEYTCIAINQAGESKKKFSLTVYVP--PSIKDHDSESLSVVNVREGT 3075
Query: 143 LMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVA 202
+ L C+++ P I W+KN + I E + + L + D
Sbjct: 3076 SVSLECESNAVPPPV-ITWYKNGRMIT-------ESTHVEILADGQMLHIKKAEVSDTGQ 3127
Query: 203 VICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQE-------GQPLILTCESKGK 255
+CR + + + V Y P PS P+ P+ LTC++ G
Sbjct: 3128 YVCRAINVAGRDDKNFHLNV----YVP-----PSIEGPEREVIVETISNPVTLTCDATGI 3178
Query: 256 PLPEPVLWTKDGGELPDPD----RMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEY 311
P P + W K+ + + D R++ G +L I +D+G Y C A+N G++ Y
Sbjct: 3179 P-PPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYY 3237
Query: 312 VLIVHDVPN 320
L + P+
Sbjct: 3238 FLSIQVPPS 3246
Score = 68.6 bits (166), Expect = 1e-11
Identities = 72/320 (22%), Positives = 120/320 (37%), Gaps = 41/320 (12%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSI 91
+ ++V+ LTC + W + D + L + +
Sbjct: 3536 EEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEV-----------L 3584
Query: 92 SVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSP----VMEGDLMQLT 147
+S + D G+YTC + K YL + VP P I+G P V+ + L
Sbjct: 3585 RISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVP--PNIAGTDEPRDITVLRNRQVTLE 3642
Query: 148 CKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSD--DGVAVIC 205
CK+ P I W +N + ++ A + +S +++ +D D C
Sbjct: 3643 CKSDAVPPPV-ITWLRNGERLQ---------ATPRVRILSGGRYLQINNADLGDTANYTC 3692
Query: 206 RVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTK 265
+ + T + +L ++ P++K P + + +L C ++G P P + W K
Sbjct: 3693 VASNIAGKTTREF---ILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPR-ITWRK 3748
Query: 266 DGGELPDPDRM--VVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLL 323
DG L ++ L+I + TD G Y C ATN G L VH +
Sbjct: 3749 DGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH------V 3802
Query: 324 PTTIIPSLTTATVTTTVAIT 343
P +I P T TV V T
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTT 3822
Score = 67.0 bits (162), Expect = 3e-11
Identities = 75/322 (23%), Positives = 121/322 (37%), Gaps = 36/322 (11%)
Query: 34 VTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISV 93
+ V G + L C V ++ W + + L + I + +
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHI-----------LQL 2350
Query: 94 SDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISG-FSSP----VMEGDLMQLTC 148
++ +SD G+Y C + T K Y L V P I G SP V+E + + LTC
Sbjct: 2351 KNIHVSDTGRYVCVAVNVAGMTDKKY--DLSVHAPPSIIGNHRSPENISVVEKNSVSLTC 2408
Query: 149 KTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVD 208
+ SG P I WFK+ + ++ R + +T++ D C V
Sbjct: 2409 EASGI-PLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTME-------DAGQYTCVVR 2460
Query: 209 HESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGG 268
+ + + VL + + +E Q + LTCE G P+PE + W KDG
Sbjct: 2461 NAAGEERKIFGLSVLVPPHIVGENTLEDVKV-KEKQSVTLTCEVTGNPVPE-ITWHKDGQ 2518
Query: 269 ELPDPD--RMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLLPTT 326
L + + ++ GR L I + G Y C A++ G S + L N + T
Sbjct: 2519 PLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSL------NVFVSPT 2572
Query: 327 IIPSLTTATVTTTVAITTSPTT 348
I + I SPT+
Sbjct: 2573 IAGVGSDGNPEDVTVILNSPTS 2594
Score = 65.1 bits (157), Expect = 1e-10
Identities = 74/298 (24%), Positives = 113/298 (37%), Gaps = 33/298 (11%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSI 91
Q ++ +EG L C+ N S+ WS KK + ++ + S+
Sbjct: 988 QILSTIEGIPVTLPCKASGNPKPSVIWS-----------KKGELISTSSAKFSAGADGSL 1036
Query: 92 SVSDVSLSDEGQYTCSLF-TMPVKTSKAYLTVLGVPE-------KPQISGFSSPVMEGDL 143
V + G+Y C+ T K LTV P Q V+ G+
Sbjct: 1037 YVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEE 1096
Query: 144 MQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAV 203
+ L C+ S P I W K + I + R TF S ++ R+ D
Sbjct: 1097 VTLPCEVK-SLPPPIITWAKETQLISPF-------SPRHTFLPSGSMKITETRTSDSGMY 1148
Query: 204 ICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLW 263
+C + + N T V L +H P ++ P Q GQ + + C ++G PLP + W
Sbjct: 1149 LCVATNIAGNVTQAVK---LNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLP-VITW 1204
Query: 264 TKDGGELPDPDRMVVSGRE--LNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
+K G + VS + L+I +D G Y C ATN G E L V + P
Sbjct: 1205 SKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPP 1262
Score = 65.1 bits (157), Expect = 1e-10
Identities = 63/247 (25%), Positives = 104/247 (42%), Gaps = 36/247 (14%)
Query: 91 ISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISG-----FSSPVMEGDLMQ 145
+ + +SD YTC + + K++ + VP P I G + V+ +
Sbjct: 1603 LHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVP--PMIEGNLATPLNKQVVIAHSLT 1660
Query: 146 LTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVIC 205
L CK +G+ P+ + W K+ +K ++ E +K +S+ +DR + V
Sbjct: 1661 LECKAAGN-PSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQ---EIDRGQY-ICVAT 1715
Query: 206 RVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLI--------LTCESKGKPL 257
V E EI Y V + P+ E I L C G P
Sbjct: 1716 SVAGEK------------EIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP- 1762
Query: 258 PEPVLWTKDGGELPDPD--RMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIV 315
P ++W KDG + + D +++++GR+L I ++ G YRC A NT G E+ + V
Sbjct: 1763 PPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTV 1822
Query: 316 HDVPNTL 322
H VP T+
Sbjct: 1823 H-VPPTI 1828
Score = 65.1 bits (157), Expect = 1e-10
Identities = 77/295 (26%), Positives = 114/295 (38%), Gaps = 32/295 (10%)
Query: 34 VTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISV 93
V V EG + L C + + W Y + + +E++ A L I
Sbjct: 3069 VNVREGTSVSLECESNAVPPPVITW--------YKNGRMITESTHVEIL-ADGQMLHIKK 3119
Query: 94 SDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDL---MQLTCKT 150
++VS D GQY C + + K + + VP P I G V+ + + LTC
Sbjct: 3120 AEVS--DTGQYVCRAINVAGRDDKNFHLNVYVP--PSIEGPEREVIVETISNPVTLTCDA 3175
Query: 151 SGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHE 210
+G P I W KN K I++ L+ + + S L + D C +
Sbjct: 3176 TGIPPPT-IAWLKNHKRIENSDSLEV-----RILSGGSKLQIARSQHSDSGNYTCIASNM 3229
Query: 211 SLNATPQVAMQVLEIHYTPSVK--IIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGG 268
A L I PSV IPS G+ + L C + G P P + W KDG
Sbjct: 3230 EGKAQKYY---FLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL-IQWLKDGK 3285
Query: 269 ELPDPD----RMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
+ + R+ +G LNI +D G Y C ATN G+ + L V+ P
Sbjct: 3286 PIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Score = 63.9 bits (154), Expect = 3e-10
Identities = 68/299 (22%), Positives = 117/299 (39%), Gaps = 36/299 (12%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSI 91
+N++VVE + LTC S+ W + + L R+ +
Sbjct: 2394 ENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRM-----------L 2442
Query: 92 SVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSS----PVMEGDLMQLT 147
+ ++ D GQYTC + + K + + VP P I G ++ V E + LT
Sbjct: 2443 RLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVP--PHIVGENTLEDVKVKEKQSVTLT 2500
Query: 148 CKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRV 207
C+ +G+ P +I W K+ + + +ED + L + C
Sbjct: 2501 CEVTGN-PVPEITWHKDGQPL-------QEDEAHHIISGGRFLQITNVQVPHTGRYTCLA 2552
Query: 208 DHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQE-----GQPLILTCESKGKPLPEPVL 262
+ + + ++ V +P++ + S P++ P L CE+ P P +
Sbjct: 2553 SSPAGHKSRSFSLNVF---VSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYP-PATIT 2608
Query: 263 WTKDGGELPDPD--RMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
W KDG L R++ GR L IL + + G Y C ATN G+ Y + V+ P
Sbjct: 2609 WFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPP 2667
Score = 63.2 bits (152), Expect = 5e-10
Identities = 72/280 (25%), Positives = 118/280 (42%), Gaps = 37/280 (13%)
Query: 99 SDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSP----VMEGDLMQLTCKTSGSK 154
SD G YTC M K K Y + VP P ++G P V+ G+ ++L C +G
Sbjct: 3217 SDSGNYTCIASNMEGKAQKYYFLSIQVP--PSVAGAEIPSDVSVLLGENVELVCNANGI- 3273
Query: 155 PAADIRWFKNDKEIKDVKYLK-EEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLN 213
P I+W K+ K I + + AN T + L SD G +
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALT-----SDTGKYTCVATNP---- 3324
Query: 214 ATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLI--------LTCESKGKPLPEPVLWTK 265
A + + L ++ TP+++ E + L+ + C + G P P+ + W K
Sbjct: 3325 AGEEDRIFNLNVYVTPTIR-----GNKDEAEKLMTLVDTSINIECRATGTPPPQ-INWLK 3378
Query: 266 DGGELPDPD--RMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPN--T 321
+G LP R++ +G+ + I+ +D Y C A+N G + Y L V PN
Sbjct: 3379 NGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDN 3438
Query: 322 LLPTTIIPSLTTATVTTTVAITTSPTTSATTSSIRDPNAL 361
+ T I L + +T++A T T + + + +RD L
Sbjct: 3439 SMGTEEITVLKGS--STSMACITDGTPAPSMAWLRDGQPL 3476
Score = 62.8 bits (151), Expect = 6e-10
Identities = 65/264 (24%), Positives = 118/264 (44%), Gaps = 43/264 (16%)
Query: 93 VSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVP----EKPQISGFSSPVMEGDLMQLTC 148
++ V+ D G+Y C T + Y + VP +K Q++ S V+ L L C
Sbjct: 1325 IASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVS--VLLNQLTNLFC 1382
Query: 149 KTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVD 208
+ G+ P+ I W+K++ ++ + ++ + N K + FR D G R
Sbjct: 1383 EVEGT-PSPIIMWYKDNVQVTESSTIQTVN-NGKILKL-----FRATPEDAG-----RYS 1430
Query: 209 HESLN--ATPQVAMQVLEIHYTPSVKIIPSTPFPQE-----GQPLILTCESKGKPLPEPV 261
+++N T Q + ++ P+ I T FP E + + L C+ KG P P+ +
Sbjct: 1431 CKAINIAGTSQKYFNI-DVLVPPT---IIGTNFPNEVSVVLNRDVALECQVKGTPFPD-I 1485
Query: 262 LWTKDGGEL--PDPD-RMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDV 318
W KDG L DP+ ++ G+ L++ + D G Y+C +N G+ + + L ++
Sbjct: 1486 HWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY-- 1543
Query: 319 PNTLLPTTIIPSLTTATVTTTVAI 342
I PS+ VTT +++
Sbjct: 1544 --------IPPSIKGGNVTTDISV 1559
Score = 62.4 bits (150), Expect = 8e-10
Identities = 65/290 (22%), Positives = 112/290 (38%), Gaps = 27/290 (9%)
Query: 33 NVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSIS 92
NVTV G A+LTC + + +L W + D + RI + LS+
Sbjct: 528 NVTVTPGERAVLTCLIISAVDYNLTWQRNDR------DVRLAEPARIRTLA----NLSLE 577
Query: 93 VSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTSG 152
+ V +D G+Y C + + ++ + + P K + + G + + C +G
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATG 637
Query: 153 SKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESL 212
P I W ND I ++R T TL + D C + +
Sbjct: 638 -YPKPKIAWTVNDMFI--------VGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAG 688
Query: 213 NATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPD 272
++ +E P + ++ S G ++ C++ G P P+ V W K EL
Sbjct: 689 TDKQNSTLRYIE---APKLMVVQSELLVALGDITVMECKTSGIPPPQ-VKWFKGDLEL-R 743
Query: 273 PDRMVVSGRELNILFLNKT---DNGTYRCEATNTIGQSSAEYVLIVHDVP 319
P ++ L +L + +T D G Y C A N G+++ + L V P
Sbjct: 744 PSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPP 793
Score = 62.0 bits (149), Expect = 1e-09
Identities = 73/314 (23%), Positives = 126/314 (40%), Gaps = 47/314 (14%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSI 91
+ V + T L C + SL W Y D + D+ + + A+ H L I
Sbjct: 2682 KEVKIKVNNTLTLECEAYAIPSASLSW--------YKDGQPLKSDDHVNIA-ANGHTLQI 2732
Query: 92 SVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQI------------SGFSSPVM 139
+ +SD G+YTC + + + + VP Q +G + V+
Sbjct: 2733 K--EAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVI 2790
Query: 140 EGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRS-- 197
+ + L C+T+ + P + W+K+ + ++ K + ++ R+
Sbjct: 2791 INNPISLYCETNAAPPPT-LTWYKDGHPLT---------SSDKVLILPGGRVLQIPRAKV 2840
Query: 198 DDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLI-----LTCES 252
+D C +E+ + Q ++VL P + ++ P+E L+ + C S
Sbjct: 2841 EDAGRYTCVAVNEAGEDSLQYDVRVL----VPPIIKGANSDLPEEVTVLVNKSALIECLS 2896
Query: 253 KGKPLPEPVLWTKDGGELPDPD--RMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAE 310
G P P W KDG L + D + + +GR L IL TD G Y C A NT G +
Sbjct: 2897 SGSPAPRNS-WQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKY 2955
Query: 311 YVLIVHDVPNTLLP 324
+ L VH P+ + P
Sbjct: 2956 FNLNVHVPPSVIGP 2969
Score = 61.6 bits (148), Expect = 1e-09
Identities = 70/295 (23%), Positives = 118/295 (40%), Gaps = 31/295 (10%)
Query: 33 NVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSIS 92
+V++ G L C V +++W ++ + + I +R ++
Sbjct: 801 DVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIF---SRPFSVSSISQLRTG----ALF 853
Query: 93 VSDVSLSDEGQYTCSLFTMPVKT-SKAYLTVLG-VPEKPQISGFSSPVMEGDLMQLTCKT 150
+ ++ SD+G Y C K S+ +TV G V IS + V+EG + L C
Sbjct: 854 ILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTL 913
Query: 151 SGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSD--DGVAVICRVD 208
P + RW KN + Y+ TV S ++R DG C
Sbjct: 914 LAGNPIPERRWIKNSAMLLQNPYI----------TVRSDGSLHIERVQLQDGGEYTCVAS 963
Query: 209 HES--LNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKD 266
+ + N T V + VL P+++ EG P+ L C++ G P P V+W+K
Sbjct: 964 NVAGTNNKTTSVVVHVL-----PTIQHGQQILSTIEGIPVTLPCKASGNPKPS-VIWSKK 1017
Query: 267 GGELPDPDRMVVSGRE--LNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
G + +G + L ++ ++G Y C ATNT G + + L V+ P
Sbjct: 1018 GELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRP 1072
Score = 61.2 bits (147), Expect = 2e-09
Identities = 56/237 (23%), Positives = 96/237 (40%), Gaps = 17/237 (7%)
Query: 91 ISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISG--FSSPVMEGDLMQLTC 148
+ ++ L D G+YTC +T + + P + +G + V+ + +QL C
Sbjct: 1883 LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLEC 1942
Query: 149 KTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVD 208
K +G+ P I W+K+++ L + +D + D C V
Sbjct: 1943 KAAGN-PVPVITWYKDNR-------LLSGSTSMTFLNRGQIIDIESAQISDAGIYKC-VA 1993
Query: 209 HESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGG 268
S AT L++H PS+ + P+ L CE++G P P + W KDG
Sbjct: 1994 INSAGATE--LFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPS-LTWLKDGS 2050
Query: 269 ELPDPD---RMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTL 322
+ +++ GR L + +D G Y C A N G+ + L V+ PN +
Sbjct: 2051 PVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIM 2107
Score = 59.3 bits (142), Expect = 7e-09
Identities = 78/358 (21%), Positives = 137/358 (38%), Gaps = 38/358 (10%)
Query: 44 LTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVSLSDEGQ 103
L C V + ++ W Q D K L + R + ++ +S+ G
Sbjct: 1754 LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGR-----------KLVIAQAQVSNTGL 1802
Query: 104 YTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVM-EGDLMQLTCKTSGSKPAADIRWF 162
Y C K + + VP + SG S V+ + + L C +G P I W
Sbjct: 1803 YRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGI-PNPSITWL 1861
Query: 163 KNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQV 222
K+D+ + + + ++ + ++ TL +D C + NA + +
Sbjct: 1862 KDDQPVNTAQGNLKIQSSGRVLQIAKTL------LEDAGRYTC----VATNAAGETQQHI 1911
Query: 223 -LEIHYTPSV----KIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMV 277
L +H PS+ K++ T P+ L C++ G P+P + W KD L M
Sbjct: 1912 QLHVHEPPSLEDAGKMLNETVLVSN--PVQLECKAAGNPVPV-ITWYKDNRLLSGSTSMT 1968
Query: 278 V--SGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLLPTTIIPSLTTAT 335
G+ ++I +D G Y+C A N+ G + Y L VH P+ ++ +
Sbjct: 1969 FLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNP 2028
Query: 336 VTTTVAITTSPTTSATTSSIRDPNALAGQNGPDHALIGGIVAVVVFVTLCSIFLLGRY 393
V P S T ++D + ++ + L GG ++ +T I GRY
Sbjct: 2029 VRLECEARGIPAPSLTW--LKDGSPVSSFSNGLQVLSGG---RILALTSAQISDTGRY 2081
Score = 58.9 bits (141), Expect = 9e-09
Identities = 59/232 (25%), Positives = 98/232 (42%), Gaps = 16/232 (6%)
Query: 90 SISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCK 149
S+ ++ V D G YTC + +S + + VP + + + V E L C
Sbjct: 4132 SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCV 4191
Query: 150 TSGSKPAADIRWFKNDKEIKDV--KYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRV 207
G P I W K++ + ++ KY E + V D G C
Sbjct: 4192 ADGI-PTPAINWKKDNVLLANLLGKYTAEP--------YGELILENVVLEDSGFYT-CVA 4241
Query: 208 DHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDG 267
++ + T V+ L +H P+ +P +G+ L L+C++ G PLP+ + WT +
Sbjct: 4242 NNAAGEDTHTVS---LTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPK-LTWTFNN 4297
Query: 268 GELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
+P V EL I ++K D+GTY C A N++G A + V + P
Sbjct: 4298 NIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPP 4349
Score = 55.8 bits (133), Expect = 7e-08
Identities = 62/291 (21%), Positives = 100/291 (34%), Gaps = 25/291 (8%)
Query: 34 VTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISV 93
++V+ G L C V + W+ Q F + + S+ +
Sbjct: 1089 ISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG-----------SMKI 1137
Query: 94 SDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGS 153
++ SD G Y C + ++A + VP K Q V G + + C G+
Sbjct: 1138 TETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGT 1197
Query: 154 KPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLN 213
P I W K + D TL D C + +
Sbjct: 1198 -PLPVITWSKGGSTML-------VDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGT 1249
Query: 214 ATPQVAMQVLEIHYTPSVKIIPSTPFPQE--GQPLILTCESKGKPLPEPVLWTKDGGELP 271
++ + V E ++ +T F + Q + C +KG P P + W +G EL
Sbjct: 1250 DETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPT-IKWLHNGRELT 1308
Query: 272 DPD---RMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
+ ++ G L I + DNG Y C A N G + +Y L VH P
Sbjct: 1309 GREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPP 1359
Score = 55.8 bits (133), Expect = 7e-08
Identities = 68/290 (23%), Positives = 117/290 (40%), Gaps = 34/290 (11%)
Query: 36 VVEGGTAILTCRVDQNDNTSLQWSNPAQQTL-YFDDKKALRDNRIELVRASWHELSISVS 94
V + A++TC S+ W+ + L D + L IE++
Sbjct: 3908 VTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQ--------- 3958
Query: 95 DVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSP--VMEGDLMQLTCKTSG 152
L+ G+YTC + ++ ++T L V E P I S V+ + + L C+ +G
Sbjct: 3959 ---LNHAGRYTC-VARNAAGSAHRHVT-LHVHEPPVIQPQPSELHVILNNPILLPCEATG 4013
Query: 153 SKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRS--DDGVAVICRVDHE 210
+ P+ I W K + + + + V + ++ R+ +D +C +
Sbjct: 4014 T-PSPFITWQKEGINV---------NTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNP 4063
Query: 211 SLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGEL 270
+ A ++ L + P + +P+ L+CE+ G P P+ + W KDG +
Sbjct: 4064 AGTALGKIK---LNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPD-ITWHKDGRAI 4119
Query: 271 PDPDRM-VVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
+ R V+S L I F+ D G Y C A N G SS L VH P
Sbjct: 4120 VESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPP 4169
Score = 55.5 bits (132), Expect = 1e-07
Identities = 74/305 (24%), Positives = 119/305 (39%), Gaps = 35/305 (11%)
Query: 25 QGQFPLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRA 84
+G N VV + L C+ N + L W D ++ N + A
Sbjct: 1642 EGNLATPLNKQVVIAHSLTLECKAAGNPSPILTW---------LKDGVPVKANDNIRIEA 1692
Query: 85 SWHELSI-SVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSP----VM 139
+L I S ++ D GQY C ++ + Y + VP P I G VM
Sbjct: 1693 GGKKLEIMSAQEI---DRGQYICVATSVAGEKEIKYEVDVLVP--PAIEGGDETSYFIVM 1747
Query: 140 EGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDD 199
+L++L C +GS P I W +KD + + E D + + + S+
Sbjct: 1748 VNNLLELDCHVTGSPPPT-IMW------LKDGQLIDERDGFKILLNGRKLVIAQAQVSNT 1800
Query: 200 GVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIP-STPFPQEGQPLILTCESKGKPLP 258
G+ C + + + + + V H P++K S + +P+ L C + G P P
Sbjct: 1801 GL-YRCMAANTAGDHKKEFEVTV---HVPPTIKSSGLSERVVVKYKPVALQCIANGIPNP 1856
Query: 259 EPVLWTKDGGELPDPD---RMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIV 315
+ W KD + ++ SGR L I D G Y C ATN G++ L V
Sbjct: 1857 S-ITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915
Query: 316 HDVPN 320
H+ P+
Sbjct: 1916 HEPPS 1920
Score = 53.9 bits (128), Expect = 3e-07
Identities = 57/234 (24%), Positives = 94/234 (40%), Gaps = 18/234 (7%)
Query: 91 ISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTV-LGVPEKPQISGFSSPVMEGDLMQLTCK 149
+ + ++D G+Y C + T T + + + + VP + V+ L C+
Sbjct: 3768 LHIQSAHVTDTGRYLC-MATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACE 3826
Query: 150 TSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTV--SSTLDFRVDRSDDGVAVICRV 207
+G P I W KN +L D N+ ++ + S +L DD C V
Sbjct: 3827 ATGI-PKPSINWRKNG-------HLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTV 3878
Query: 208 DHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDG 267
+ + + V L + PS+ P+ + P ++TC + G P P + WTK+G
Sbjct: 3879 TNGAGDDKRTVD---LTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPS-IHWTKNG 3934
Query: 268 GE-LPDPD-RMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319
LP D ++S + IL G Y C A N G + L VH+ P
Sbjct: 3935 IRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 52.8 bits (125), Expect = 6e-07
Identities = 66/273 (24%), Positives = 108/273 (39%), Gaps = 26/273 (9%)
Query: 89 LSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSS--PVMEGDLMQL 146
+++ ++ V+LSDEG Y C + T +A T V E P + + V G+ L
Sbjct: 482 VNLDIAKVTLSDEGFYEC-IAVSSAGTGRAQ-TFFDVSEPPPVIQVPNNVTVTPGERAVL 539
Query: 147 TCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICR 206
TC S ++ W +ND++++ E A +T + +L+ + + +D C
Sbjct: 540 TCLII-SAVDYNLTWQRNDRDVR-----LAEPARIRTL-ANLSLELKSVKFNDAGEYHCM 592
Query: 207 VDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKD 266
V E ++ V + V E P V ++P G + + C + G P P+ + WT +
Sbjct: 593 VSSEGGSSAASVFLTVQE---PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPK-IAWTVN 648
Query: 267 GGELPDPDR-MVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLLPT 325
+ R + S L I D G Y C A+N+ G D N+ L
Sbjct: 649 DMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGT----------DKQNSTLRY 698
Query: 326 TIIPSLTTATVTTTVAITTSPTTSATTSSIRDP 358
P L VA+ TS I P
Sbjct: 699 IEAPKLMVVQSELLVALGDITVMECKTSGIPPP 731
Score = 52.4 bits (124), Expect = 8e-07
Identities = 70/333 (21%), Positives = 121/333 (36%), Gaps = 30/333 (9%)
Query: 23 GSQGQFPLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELV 82
GS G ++VTV+ L C +S P +F D L NR +
Sbjct: 2577 GSDGN---PEDVTVILNSPTSLVCEA---------YSYPPATITWFKDGTPLESNRN--I 2622
Query: 83 RASWHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPE--------KPQISGF 134
R ++ + + + G+Y+C + K Y + +P P +S
Sbjct: 2623 RILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPK 2682
Query: 135 SSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRV 194
+ + + L C+ P+A + W+K+ + +K ++ AN T +
Sbjct: 2683 EVKIKVNNTLTLECEAYAI-PSASLSWYKDGQPLKSDDHVNIA-ANGHTLQIKEAQISDT 2740
Query: 195 DRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQE---GQPLILTCE 251
R + I D + QV ++ ++ ++ P+ L CE
Sbjct: 2741 GRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCE 2800
Query: 252 SKGKPLPEPVLWTKDGGELPDPDRMVV--SGRELNILFLNKTDNGTYRCEATNTIGQSSA 309
+ P P + W KDG L D++++ GR L I D G Y C A N G+ S
Sbjct: 2801 TNAAP-PPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSL 2859
Query: 310 EYVLIVHDVPNTLLPTTIIPSLTTATVTTTVAI 342
+Y + V P + +P T V + I
Sbjct: 2860 QYDVRVLVPPIIKGANSDLPEEVTVLVNKSALI 2892
Score = 51.6 bits (122), Expect = 1e-06
Identities = 66/317 (20%), Positives = 113/317 (35%), Gaps = 35/317 (11%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSI 91
+++TV+ L C+ D + W ++ + L R +
Sbjct: 3629 RDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRY-----------L 3677
Query: 92 SVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTS 151
+++ L D YTC + KT++ ++ + VP + S ++ L C
Sbjct: 3678 QINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAE 3737
Query: 152 GSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHES 211
G P I W K+ + + R + + L + D +C + +
Sbjct: 3738 GV-PTPRITWRKDGAVLAG-------NHARYSILENGFLHIQSAHVTDTGRYLCMATNAA 3789
Query: 212 LNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGEL- 270
++ +QV H PS+ P+ L CE+ G P P + W K+G L
Sbjct: 3790 GTDRRRIDLQV---HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPS-INWRKNGHLLN 3845
Query: 271 ----PDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVH------DVPN 320
+ R++ SG L I+ + D TY C TN G L V D P
Sbjct: 3846 VDQNQNSYRLLSSG-SLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEPT 3904
Query: 321 TLLPTTIIPSLTTATVT 337
L T P++ T T +
Sbjct: 3905 DFLVTKHAPAVITCTAS 3921
Score = 49.7 bits (117), Expect = 5e-06
Identities = 64/273 (23%), Positives = 99/273 (36%), Gaps = 24/273 (8%)
Query: 91 ISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKT 150
+ + + D G YTC + + +G P + G + L C
Sbjct: 757 LKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYV 816
Query: 151 SGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDR--------SDDGVA 202
G P I+W + L + F+VSS R SD G
Sbjct: 817 QGY-PEPTIKW----------RRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGT- 864
Query: 203 VICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCES-KGKPLPEPV 261
IC +++ + + V + P + I PS EGQ L L C G P+PE
Sbjct: 865 YICEAENQFGKIQSETTVTVTGL-VAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPER- 922
Query: 262 LWTKDGGEL-PDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPN 320
W K+ L +P V S L+I + D G Y C A+N G ++ ++VH +P
Sbjct: 923 RWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPT 982
Query: 321 TLLPTTIIPSLTTATVTTTVAITTSPTTSATTS 353
I+ ++ VT + +P S S
Sbjct: 983 IQHGQQILSTIEGIPVTLPCKASGNPKPSVIWS 1015
Score = 49.7 bits (117), Expect = 5e-06
Identities = 62/239 (25%), Positives = 96/239 (40%), Gaps = 23/239 (9%)
Query: 91 ISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVME------GDLM 144
+ + + D G+YTC + S Y + VP P I G +S + E
Sbjct: 2833 LQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVP--PIIKGANSDLPEEVTVLVNKSA 2890
Query: 145 QLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVI 204
+ C +SGS PA W K+ + + ED + K + L + D +
Sbjct: 2891 LIECLSSGS-PAPRNSWQKDGQPLL-------EDDHHKFLSNGRILQILNTQITDIGRYV 2942
Query: 205 CRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLI-LTCESKGKPLPEPVLW 263
C ++ + +A L +H PSV S I LTCE G P P+ + W
Sbjct: 2943 CVAENTAGSAKKYFN---LNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPD-LSW 2998
Query: 264 TKDGG--ELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPN 320
K+ +L +V GR L I+ +D G Y C A N G+S ++ L V+ P+
Sbjct: 2999 LKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPS 3057
Score = 49.7 bits (117), Expect = 5e-06
Identities = 78/305 (25%), Positives = 118/305 (38%), Gaps = 39/305 (12%)
Query: 20 KVKGSQGQFPLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRI 79
+++ ++G + TV E AIL C D ++ W D L +
Sbjct: 4170 RIRSTEGHY------TVNENSQAILPCVADGIPTPAINWKK---------DNVLLANLLG 4214
Query: 80 ELVRASWHELSISVSDVSLSDEGQYTCSLFTMPVK-TSKAYLTVLGVPEKPQISGFSSPV 138
+ + EL + +V L D G YTC + T LTV +P ++ G S +
Sbjct: 4215 KYTAEPYGELILE--NVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVS-L 4271
Query: 139 MEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDF-RVDRS 197
+G+ ++L+CK +G P + W N+ I A+ + S L RV +
Sbjct: 4272 NKGEQLRLSCKATGI-PLPKLTWTFNNNIIP---------AHFDSVNGHSELVIERVSKE 4321
Query: 198 DDGVAVICRVDHESLNATPQV-AMQVLEIHYTPSVK-IIPSTPFPQEGQPLILTCESKGK 255
D G V C + N+ V A+ + + P K PS G IL CE KG
Sbjct: 4322 DSGTYV-CTAE----NSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGD 4376
Query: 256 PLPEPVLWTKDGGELPDPDRMVVSGR-ELNILFLNKTDNGTYRCEATNTIGQSSAEYVLI 314
P P + W + G ++ R+ G L I D G Y C ATN G L
Sbjct: 4377 PTPT-IQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLT 4435
Query: 315 VHDVP 319
+ P
Sbjct: 4436 LQSPP 4440
Score = 47.8 bits (112), Expect = 2e-05
Identities = 52/230 (22%), Positives = 93/230 (40%), Gaps = 25/230 (10%)
Query: 93 VSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLG---VPEKPQISG-FSSPVME--GDLMQL 146
+ VS D G Y C+ + S ++ +G V E P G + S +E G L
Sbjct: 4315 IERVSKEDSGTYVCT-----AENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAIL 4369
Query: 147 TCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICR 206
C+ G P I+W + +I+ +++ + + T++ +D C
Sbjct: 4370 NCEVKGD-PTPTIQWNRKGVDIEISHRIRQ--LGNGSLAIYGTVN------EDAGDYTCV 4420
Query: 207 VDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKD 266
+E+ ++ L + P + + P G +IL C++ G+P P + W++
Sbjct: 4421 ATNEAGVVERSMS---LTLQSPPIITLEPVETVINAGGKIILNCQATGEPQP-TITWSRQ 4476
Query: 267 GGELPDPDRM-VVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIV 315
G + DR+ V+S L I K D + C A N +G +IV
Sbjct: 4477 GHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 30.0 bits (66), Expect = 4.3
Identities = 26/130 (20%), Positives = 45/130 (34%), Gaps = 13/130 (10%)
Query: 39 GGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVSL 98
GG AIL C V + ++QW+ + L + S+++
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNG------------SLAIYGTVN 4411
Query: 99 SDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGSKPAAD 158
D G YTC ++ L P + + + G + L C+ +G +P
Sbjct: 4412 EDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATG-EPQPT 4470
Query: 159 IRWFKNDKEI 168
I W + I
Sbjct: 4471 ITWSRQGHSI 4480
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 77.8 bits (190), Expect = 2e-14
Identities = 80/317 (25%), Positives = 128/317 (40%), Gaps = 31/317 (9%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSI 91
Q+V V G T TCR + N + W + +L +D D R+ + + + ++
Sbjct: 241 QDVEVPSGNTVYFTCRAEGNPKPEIIWIHN-NHSLDLED-----DTRLNV----FDDGTL 290
Query: 92 SVSDVSLSDEGQYTCSLFTMP--VKTSKAYLTVLGVPEKPQ--ISGFSSPVMEGDLMQLT 147
+ + SD+G Y C KT A L +P KP I + V+ G L
Sbjct: 291 MIRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVIQPQDTEVLIGTSTTLE 350
Query: 148 CKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRV 207
C +G P I W +++ E D +R T S + + D G C
Sbjct: 351 CMATGH-PHPLITWTRDNG--------LELDGSRHVATSSGLYLQNITQRDHG-RFTCHA 400
Query: 208 DHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDG 267
++ + T Q A ++ + P + P E + CE+ G P P ++WTK G
Sbjct: 401 NNS--HGTVQAAANII-VQAPPQFTVTPKDQVVLEEHAVEWLCEADGNP-PPVIVWTKTG 456
Query: 268 GELP-DPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLLPTT 326
G+LP + V+S L I + D G Y C+A +++G L V P L T
Sbjct: 457 GQLPVEGQHTVLSSGTLRIDRAAQHDQGQYECQAVSSLGVKKVSVQLTVK--PKALAVFT 514
Query: 327 IIPSLTTATVTTTVAIT 343
+P T+ V + I+
Sbjct: 515 QLPQDTSVEVGKNINIS 531
Score = 49.7 bits (117), Expect = 5e-06
Identities = 62/297 (20%), Positives = 114/297 (38%), Gaps = 49/297 (16%)
Query: 32 QNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSI 91
Q+ V+ G + L C + + + W+ RDN +EL S H +
Sbjct: 337 QDTEVLIGTSTTLECMATGHPHPLITWT---------------RDNGLEL-DGSRHVATS 380
Query: 92 S---VSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTC 148
S + +++ D G++TC A ++ P + ++ V+E ++ C
Sbjct: 381 SGLYLQNITQRDHGRFTCHANNSHGTVQAAANIIVQAPPQFTVTPKDQVVLEEHAVEWLC 440
Query: 149 KTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRS---DDGVAVIC 205
+ G+ P I W K ++ TV S+ R+DR+ D G
Sbjct: 441 EADGNPPPV-IVWTKTGGQLPV----------EGQHTVLSSGTLRIDRAAQHDQG----- 484
Query: 206 RVDHESLNATPQVAMQVLEIHYTPSVKIIPS-TPFPQE-----GQPLILTCESKGKPLPE 259
A + ++ + + T K + T PQ+ G+ + ++C ++G+P P
Sbjct: 485 ---QYECQAVSSLGVKKVSVQLTVKPKALAVFTQLPQDTSVEVGKNINISCHAQGEPQPI 541
Query: 260 PVLWTKDGGELPDPDRMVVSGR-ELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIV 315
+ W K+G ++ + + V L I D G Y C A N+ G + L V
Sbjct: 542 -ITWNKEGVQITESGKFHVDDEGTLTIYDAGFPDQGRYECVARNSFGLAVTNMFLTV 597
Score = 42.0 bits (97), Expect = 0.001
Identities = 33/123 (26%), Positives = 54/123 (43%), Gaps = 10/123 (8%)
Query: 228 TPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGG--ELPDPDRM-VVSGRELN 284
+P + P G + TC ++G P PE ++W + +L D R+ V L
Sbjct: 233 SPRITFEPQDVEVPSGNTVYFTCRAEGNPKPE-IIWIHNNHSLDLEDDTRLNVFDDGTLM 291
Query: 285 ILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLLPTTIIPSLTTATVTTTVAITT 344
I ++D G Y+C A N+ G++ + ++ + + LP PS T V I T
Sbjct: 292 IRNTRESDQGVYQCMARNSAGEAKTQSAMLRY----SSLPAK--PSFVIQPQDTEVLIGT 345
Query: 345 SPT 347
S T
Sbjct: 346 STT 348
>gi|145275174 kin of IRRE-like 2 isoform c [Homo sapiens]
Length = 708
Score = 77.8 bits (190), Expect = 2e-14
Identities = 57/227 (25%), Positives = 96/227 (42%), Gaps = 8/227 (3%)
Query: 91 ISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQI-SGFSSPVMEGDLMQLTCK 149
+ + V L DE Y C +++ A L VL PE PQ+ G S ++ G LTC+
Sbjct: 88 LHIRPVELEDEASYECQATQAGLRSRPAQLHVLVPPEAPQVLGGPSVSLVAGVPANLTCR 147
Query: 150 TSG-SKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVD 208
+ G ++P ++ WF++ + + + +V STL DDG +CR
Sbjct: 148 SRGDARPTPELLWFRDGVLLDGATFHQTLLKEGTPGSVESTLTLTPFSHDDGATFVCRAR 207
Query: 209 HESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGG 268
++L A+ L + Y P V + S QEG+ +I C++ +P W K G
Sbjct: 208 SQALPTGRDTAI-TLSLQYPPEVTLSASPHTVQEGEKVIFLCQATAQPPVTGYRWAKGGS 266
Query: 269 ELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIV 315
+ + G L ++ CE +N +G ++ L V
Sbjct: 267 PV-----LGARGPRLEVVADASFLTEPVSCEVSNAVGSANRSTALDV 308
Score = 58.5 bits (140), Expect = 1e-08
Identities = 72/343 (20%), Positives = 124/343 (36%), Gaps = 39/343 (11%)
Query: 33 NVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKAL-----RDNRIELVRASWH 87
+V++V G A LTCR S + P + L+F D L ++
Sbjct: 133 SVSLVAGVPANLTCR-------SRGDARPTPELLWFRDGVLLDGATFHQTLLKEGTPGSV 185
Query: 88 ELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSP--VMEGDLMQ 145
E +++++ S D + C + + T + L + P+++ +SP V EG+ +
Sbjct: 186 ESTLTLTPFSHDDGATFVCRARSQALPTGRDTAITLSLQYPPEVTLSASPHTVQEGEKVI 245
Query: 146 LTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVIC 205
C+ + P RW K + + L+ D S V C
Sbjct: 246 FLCQATAQPPVTGYRWAKGGSPVLGAR--------------GPRLEVVADASFLTEPVSC 291
Query: 206 RVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTK 265
V + +A A+ VL + P ++ P G+ +C +G PLP V WT+
Sbjct: 292 EVSNAVGSANRSTALDVL---FGPILQAKPEPVSVDVGEDASFSCAWRGNPLPR-VTWTR 347
Query: 266 DGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIG--QSSAEYVLIVHDVPNTLL 323
GG +++ SG L + + D G Y C A + + A + + P +
Sbjct: 348 RGGA-----QVLGSGATLRLPSVGPEDAGDYVCRAEAGLSGLRGGAAEARLTVNAPPVVT 402
Query: 324 PTTIIPSLTTATVTTTVAITTSPTTSATTSSIRDPNALAGQNG 366
P+ + SP A S + AG G
Sbjct: 403 ALHSAPAFLRGPARLQCLVFASPAPDAVVWSWDEGFLEAGSQG 445
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,245,658
Number of Sequences: 37866
Number of extensions: 840511
Number of successful extensions: 7704
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 204
Number of HSP's successfully gapped in prelim test: 312
Number of HSP's that attempted gapping in prelim test: 3136
Number of HSP's gapped (non-prelim): 3503
length of query: 437
length of database: 18,247,518
effective HSP length: 105
effective length of query: 332
effective length of database: 14,271,588
effective search space: 4738167216
effective search space used: 4738167216
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.