Guide to the Human Genome
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Search of human proteins with 4507587

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507587 tumor necrosis factor receptor superfamily, member 7
precursor [Homo sapiens]
         (260 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507587 tumor necrosis factor receptor superfamily, member 7 ...   572   e-163
gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]             69   3e-12
gi|23510423 tumor necrosis factor receptor superfamily, member 6...    65   8e-11
gi|23510421 tumor necrosis factor receptor superfamily, member 6...    65   8e-11
gi|4507583 tumor necrosis factor receptor superfamily, member 6 ...    65   8e-11
gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]            63   3e-10
gi|4507579 tumor necrosis factor receptor superfamily, member 4 ...    54   1e-07
gi|5730095 tumor necrosis factor receptor superfamily, member 9 ...    54   1e-07
gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapi...    54   1e-07
gi|4505039 lymphotoxin beta receptor [Homo sapiens]                    54   1e-07
gi|23200041 tumor necrosis factor receptor superfamily, member 1...    54   2e-07
gi|23200023 tumor necrosis factor receptor superfamily, member 2...    54   2e-07
gi|23200021 tumor necrosis factor receptor superfamily, member 2...    54   2e-07
gi|89142745 tumor necrosis factor receptor superfamily, member 2...    54   2e-07
gi|4507569 tumor necrosis factor receptor superfamily, member 25...    54   2e-07
gi|14790170 tumor necrosis factor receptor superfamily, member 6...    52   4e-07
gi|4507585 tumor necrosis factor receptor superfamily, member 6b...    52   4e-07
gi|4505393 nerve growth factor receptor precursor [Homo sapiens]       52   4e-07
gi|4507577 tumor necrosis factor receptor 2 precursor [Homo sapi...    50   3e-06
gi|11140823 X-linked ectodysplasin receptor [Homo sapiens]             49   3e-06
gi|4507565 tumor necrosis factor receptor superfamily, member 11...    47   2e-05
gi|148743793 osteoprotegerin precursor [Homo sapiens]                  41   0.001
gi|21264602 laminin alpha 5 [Homo sapiens]                             40   0.002
gi|22547121 tumor necrosis factor receptor superfamily, member 1...    40   0.002
gi|22547108 tumor necrosis factor receptor superfamily, member 1...    39   0.003
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]               39   0.003
gi|4507483 thrombomodulin precursor [Homo sapiens]                     38   0.008
gi|68348711 tumor necrosis factor receptor superfamily, member 8...    38   0.010
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]                37   0.013
gi|9506545 delta-like 4 protein precursor [Homo sapiens]               37   0.023

>gi|4507587 tumor necrosis factor receptor superfamily, member 7
           precursor [Homo sapiens]
          Length = 260

 Score =  572 bits (1473), Expect = e-163
 Identities = 260/260 (100%), Positives = 260/260 (100%)

Query: 1   MARPHPWWLCVLGTLVGLSATPAPKSCPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAA 60
           MARPHPWWLCVLGTLVGLSATPAPKSCPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAA
Sbjct: 1   MARPHPWWLCVLGTLVGLSATPAPKSCPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAA 60

Query: 61  QCDPCIPGVSFSPDHHTRPHCESCRHCNSGLLVRNCTITANAECACRNGWQCRDKECTEC 120
           QCDPCIPGVSFSPDHHTRPHCESCRHCNSGLLVRNCTITANAECACRNGWQCRDKECTEC
Sbjct: 61  QCDPCIPGVSFSPDHHTRPHCESCRHCNSGLLVRNCTITANAECACRNGWQCRDKECTEC 120

Query: 121 DPLPNPSLTARSSQALSPHPQPTHLPYVSEMLEARTAGHMQTLADFRQLPARTLSTHWPP 180
           DPLPNPSLTARSSQALSPHPQPTHLPYVSEMLEARTAGHMQTLADFRQLPARTLSTHWPP
Sbjct: 121 DPLPNPSLTARSSQALSPHPQPTHLPYVSEMLEARTAGHMQTLADFRQLPARTLSTHWPP 180

Query: 181 QRSLCSSDFIRILVIFSGMFLVFTLAGALFLHQRRKYRSNKGESPVEPAEPCRYSCPREE 240
           QRSLCSSDFIRILVIFSGMFLVFTLAGALFLHQRRKYRSNKGESPVEPAEPCRYSCPREE
Sbjct: 181 QRSLCSSDFIRILVIFSGMFLVFTLAGALFLHQRRKYRSNKGESPVEPAEPCRYSCPREE 240

Query: 241 EGSTIPIQEDYRKPEPACSP 260
           EGSTIPIQEDYRKPEPACSP
Sbjct: 241 EGSTIPIQEDYRKPEPACSP 260


>gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]
          Length = 277

 Score = 69.3 bits (168), Expect = 3e-12
 Identities = 67/260 (25%), Positives = 106/260 (40%), Gaps = 20/260 (7%)

Query: 10  CVL-GTLVGLSATPAPKSCPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPG 68
           CVL G L+       P +C E+ Y    + CC +C+PG  LV DC +  +  +C PC   
Sbjct: 8   CVLWGCLLTAVHPEPPTACREKQYLINSQ-CCSLCQPGQKLVSDCTEFTE-TECLPCGES 65

Query: 69  VSFSPDHHTRPHCESCRHC--NSGLLV-RNCTITANAECACRNGWQCRDKECTEC----D 121
             F    +   HC   ++C  N GL V +  T   +  C C  GW C  + C  C     
Sbjct: 66  -EFLDTWNRETHCHQHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCTSEACESCVLHRS 124

Query: 122 PLPNPSLTARSSQALSPHPQPTHLPYVSEMLEARTAGHMQTLADFRQLPARTLSTHWPPQ 181
             P   +   ++       +P  + + S +  A    H  T  + + L  +   T+    
Sbjct: 125 CSPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHPWTSCETKDLVVQQAGTN--KT 182

Query: 182 RSLCS-SDFIRILVIFSGMF--LVFTLAGALFLHQRRKYRSNKGESPVEPAEPCRYSCPR 238
             +C   D +R LV+   +F  L   L   +F+ +  K  +NK   P +  EP   + P 
Sbjct: 183 DVVCGPQDRLRALVVIPIIFGILFAILLVLVFIKKVAKKPTNKAPHPKQ--EPQEINFPD 240

Query: 239 EEEGS--TIPIQEDYRKPEP 256
           +  GS    P+QE     +P
Sbjct: 241 DLPGSNTAAPVQETLHGCQP 260


>gi|23510423 tumor necrosis factor receptor superfamily, member 6
           isoform 3 precursor [Homo sapiens]
          Length = 220

 Score = 64.7 bits (156), Expect = 8e-11
 Identities = 29/90 (32%), Positives = 40/90 (44%), Gaps = 3/90 (3%)

Query: 36  GKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCNSGLLVR- 94
           G+ C + C PG    +DC  +     C PC  G  ++   H    C  CR C+ G  +  
Sbjct: 56  GQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEV 115

Query: 95  --NCTITANAECACRNGWQCRDKECTECDP 122
             NCT T N +C C+  + C    C  CDP
Sbjct: 116 EINCTRTQNTKCRCKPNFFCNSTVCEHCDP 145


>gi|23510421 tumor necrosis factor receptor superfamily, member 6
           isoform 2 precursor [Homo sapiens]
          Length = 314

 Score = 64.7 bits (156), Expect = 8e-11
 Identities = 29/90 (32%), Positives = 40/90 (44%), Gaps = 3/90 (3%)

Query: 36  GKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCNSGLLVR- 94
           G+ C + C PG    +DC  +     C PC  G  ++   H    C  CR C+ G  +  
Sbjct: 56  GQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEV 115

Query: 95  --NCTITANAECACRNGWQCRDKECTECDP 122
             NCT T N +C C+  + C    C  CDP
Sbjct: 116 EINCTRTQNTKCRCKPNFFCNSTVCEHCDP 145


>gi|4507583 tumor necrosis factor receptor superfamily, member 6
           isoform 1 precursor [Homo sapiens]
          Length = 335

 Score = 64.7 bits (156), Expect = 8e-11
 Identities = 29/90 (32%), Positives = 40/90 (44%), Gaps = 3/90 (3%)

Query: 36  GKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCNSGLLVR- 94
           G+ C + C PG    +DC  +     C PC  G  ++   H    C  CR C+ G  +  
Sbjct: 56  GQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEV 115

Query: 95  --NCTITANAECACRNGWQCRDKECTECDP 122
             NCT T N +C C+  + C    C  CDP
Sbjct: 116 EINCTRTQNTKCRCKPNFFCNSTVCEHCDP 145


>gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]
          Length = 203

 Score = 62.8 bits (151), Expect = 3e-10
 Identities = 37/115 (32%), Positives = 52/115 (45%), Gaps = 7/115 (6%)

Query: 10  CVL-GTLVGLSATPAPKSCPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPG 68
           CVL G L+       P +C E+ Y    + CC +C+PG  LV DC +  +  +C PC   
Sbjct: 8   CVLWGCLLTAVHPEPPTACREKQYLINSQ-CCSLCQPGQKLVSDCTEFTE-TECLPCGES 65

Query: 69  VSFSPDHHTRPHCESCRHC--NSGLLV-RNCTITANAECACRNGWQCRDKECTEC 120
             F    +   HC   ++C  N GL V +  T   +  C C  GW C  + C  C
Sbjct: 66  -EFLDTWNRETHCHQHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCTSEACESC 119


>gi|4507579 tumor necrosis factor receptor superfamily, member 4
           precursor [Homo sapiens]
          Length = 277

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 36/105 (34%), Positives = 46/105 (43%), Gaps = 8/105 (7%)

Query: 39  CCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCN--SGLLVRN- 95
           CC  C PG  +V  C + +    C PC PG  F  D  +   C+ C  CN  SG   +  
Sbjct: 42  CCHECRPGNGMVSRCSRSQNTV-CRPCGPG--FYNDVVSSKPCKPCTWCNLRSGSERKQL 98

Query: 96  CTITANAECACRNGWQCRD--KECTECDPLPNPSLTARSSQALSP 138
           CT T +  C CR G Q  D  K   +C P P    +   +QA  P
Sbjct: 99  CTATQDTVCRCRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKP 143


>gi|5730095 tumor necrosis factor receptor superfamily, member 9
           precursor [Homo sapiens]
          Length = 255

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 32/83 (38%), Positives = 39/83 (46%), Gaps = 8/83 (9%)

Query: 40  CQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCNSGLLVRN-CTI 98
           C  C  GTF    CD +R    C PC P  SFS     R  C+ CR C      R  C+ 
Sbjct: 28  CSNCPAGTF----CDNNRNQI-CSPCPPN-SFSSAGGQRT-CDICRQCKGVFRTRKECSS 80

Query: 99  TANAECACRNGWQCRDKECTECD 121
           T+NAEC C  G+ C    C+ C+
Sbjct: 81  TSNAECDCTPGFHCLGAGCSMCE 103


>gi|4507575 tumor necrosis factor receptor 1 precursor [Homo
           sapiens]
          Length = 455

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 11/104 (10%)

Query: 27  CPERHYW--AQGKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESC 84
           CP+  Y       +CC  C  GT+L  DC    +   C  C  G   + ++H R HC SC
Sbjct: 44  CPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLR-HCLSC 102

Query: 85  RHCNSGL---LVRNCTITANAECACRNG-----WQCRDKECTEC 120
             C   +    + +CT+  +  C CR       W     +C  C
Sbjct: 103 SKCRKEMGQVEISSCTVDRDTVCGCRKNQYRHYWSENLFQCFNC 146


>gi|4505039 lymphotoxin beta receptor [Homo sapiens]
          Length = 435

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 38/135 (28%), Positives = 57/135 (42%), Gaps = 21/135 (15%)

Query: 7   WWLCVLGTLVGLSATPAPKSCP-------------ERHYWAQGKLCCQMCEPGTFLVKDC 53
           W   VLG L GL A   P++ P             + +Y  Q ++CC  C PGT++   C
Sbjct: 14  WGPLVLG-LFGLLAASQPQAVPPYASENQTCRDQEKEYYEPQHRICCSRCPPGTYVSAKC 72

Query: 54  DQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCNSGL---LVRNCTITANAECACRNGW 110
            + R    C  C    S++   +    C+ CR C+  +    +  CT     +C C+ G 
Sbjct: 73  SRIRDTV-CATCAEN-SYNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKRKTQCRCQPGM 130

Query: 111 QCR--DKECTECDPL 123
            C     ECT C+ L
Sbjct: 131 FCAAWALECTHCELL 145


>gi|23200041 tumor necrosis factor receptor superfamily, member 14
           precursor [Homo sapiens]
          Length = 283

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 33/102 (32%), Positives = 46/102 (45%), Gaps = 6/102 (5%)

Query: 22  PAPKSCPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHC 81
           PA  SC E  Y   G  CC  C PG + VK+         C+PC PG ++    +    C
Sbjct: 37  PALPSCKEDEY-PVGSECCPKCSPG-YRVKEACGELTGTVCEPCPPG-TYIAHLNGLSKC 93

Query: 82  ESCRHCNSGLLVR---NCTITANAECACRNGWQCRDKECTEC 120
             C+ C+  + +R   NC+ T NA C C  G  C  ++   C
Sbjct: 94  LQCQMCDPAMGLRASRNCSRTENAVCGCSPGHFCIVQDGDHC 135


>gi|23200023 tumor necrosis factor receptor superfamily, member 25
           isoform 3 precursor [Homo sapiens]
          Length = 380

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 5/92 (5%)

Query: 36  GKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCN---SGLL 92
           G  CC+ C  G +L   C +    + C  C      + ++H    C  C+ C+   S + 
Sbjct: 44  GLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVA 103

Query: 93  VRNCTITANAECACRNGW--QCRDKECTECDP 122
           + NC+  A+  C C+ GW  +C+  +C    P
Sbjct: 104 LENCSAVADTRCGCKPGWFVECQVSQCVSSSP 135


>gi|23200021 tumor necrosis factor receptor superfamily, member 25
           isoform 1 precursor [Homo sapiens]
          Length = 426

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 5/92 (5%)

Query: 36  GKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCN---SGLL 92
           G  CC+ C  G +L   C +    + C  C      + ++H    C  C+ C+   S + 
Sbjct: 44  GLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVA 103

Query: 93  VRNCTITANAECACRNGW--QCRDKECTECDP 122
           + NC+  A+  C C+ GW  +C+  +C    P
Sbjct: 104 LENCSAVADTRCGCKPGWFVECQVSQCVSSSP 135


>gi|89142745 tumor necrosis factor receptor superfamily, member 25
           isoform 12 precursor [Homo sapiens]
          Length = 181

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 5/92 (5%)

Query: 36  GKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCN---SGLL 92
           G  CC+ C  G +L   C +    + C  C      + ++H    C  C+ C+   S + 
Sbjct: 44  GLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVA 103

Query: 93  VRNCTITANAECACRNGW--QCRDKECTECDP 122
           + NC+  A+  C C+ GW  +C+  +C    P
Sbjct: 104 LENCSAVADTRCGCKPGWFVECQVSQCVSSSP 135


>gi|4507569 tumor necrosis factor receptor superfamily, member 25
           isoform 2 precursor [Homo sapiens]
          Length = 417

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 5/92 (5%)

Query: 36  GKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCN---SGLL 92
           G  CC+ C  G +L   C +    + C  C      + ++H    C  C+ C+   S + 
Sbjct: 44  GLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVA 103

Query: 93  VRNCTITANAECACRNGW--QCRDKECTECDP 122
           + NC+  A+  C C+ GW  +C+  +C    P
Sbjct: 104 LENCSAVADTRCGCKPGWFVECQVSQCVSSSP 135


>gi|14790170 tumor necrosis factor receptor superfamily, member 6b
           [Homo sapiens]
          Length = 300

 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 47/173 (27%), Positives = 64/173 (36%), Gaps = 43/173 (24%)

Query: 9   LCVLGTLVGLSATPAPKSCPER--HYWAQG----KLCCQMCEPGTFLVKDCDQHRKAAQC 62
           LC++  L  L   PA +   E   + W       +L C  C PGTF+ + C +      C
Sbjct: 12  LCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQRPC-RRDSPTTC 70

Query: 63  DPCIPGVSFSPDHHTR--PHCESCRHCN-----SGLLVRNCTITANAECACRNGWQCRDK 115
            PC       P H+T+   + E CR+CN          R C  T N  C CR G+     
Sbjct: 71  GPC------PPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAG 124

Query: 116 EC---------------------TECDPLPNPSLTA--RSSQALSPHPQPTHL 145
            C                     T+C P P  + +A   SS+   PH   T L
Sbjct: 125 FCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTAL 177


>gi|4507585 tumor necrosis factor receptor superfamily, member 6b
           [Homo sapiens]
          Length = 300

 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 47/173 (27%), Positives = 64/173 (36%), Gaps = 43/173 (24%)

Query: 9   LCVLGTLVGLSATPAPKSCPER--HYWAQG----KLCCQMCEPGTFLVKDCDQHRKAAQC 62
           LC++  L  L   PA +   E   + W       +L C  C PGTF+ + C +      C
Sbjct: 12  LCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQRPC-RRDSPTTC 70

Query: 63  DPCIPGVSFSPDHHTR--PHCESCRHCN-----SGLLVRNCTITANAECACRNGWQCRDK 115
            PC       P H+T+   + E CR+CN          R C  T N  C CR G+     
Sbjct: 71  GPC------PPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAG 124

Query: 116 EC---------------------TECDPLPNPSLTA--RSSQALSPHPQPTHL 145
            C                     T+C P P  + +A   SS+   PH   T L
Sbjct: 125 FCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTAL 177


>gi|4505393 nerve growth factor receptor precursor [Homo sapiens]
          Length = 427

 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 46/195 (23%), Positives = 79/195 (40%), Gaps = 35/195 (17%)

Query: 15  LVGLSATPAPKSCPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPD 74
           L+G+S   A ++CP   Y   G+ CC+ C  G  + + C  ++    C+PC+  V+FS  
Sbjct: 20  LLGVSLGGAKEACPTGLYTHSGE-CCKACNLGEGVAQPCGANQTV--CEPCLDSVTFSDV 76

Query: 75  HHTRPHCESCRHCNSGL--LVRNCTITANAECACRNGW---------------------- 110
                 C+ C  C  GL  +   C    +A C C  G+                      
Sbjct: 77  VSATEPCKPCTEC-VGLQSMSAPCVEADDAVCRCAYGYYQDETTGRCEACRVCEAGSGLV 135

Query: 111 -QCRDKECTECDPLPNPSLTARSSQALSPHPQPTHLPYVSEMLEARTAGHMQTL-ADFRQ 168
             C+DK+ T C+  P+ + +  ++     H  P     V E  E +     +   A+  +
Sbjct: 136 FSCQDKQNTVCEECPDGTYSDEAN-----HVDPCLPCTVCEDTERQLRECTRWADAECEE 190

Query: 169 LPARTLSTHWPPQRS 183
           +P R ++   PP+ S
Sbjct: 191 IPGRWITRSTPPEGS 205


>gi|4507577 tumor necrosis factor receptor 2 precursor [Homo
           sapiens]
          Length = 461

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 35/109 (32%), Positives = 48/109 (44%), Gaps = 9/109 (8%)

Query: 22  PAPKS-CPERHYWAQ-GKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRP 79
           P P S C  R Y+ Q  ++CC  C PG      C +      CD C    +++   +  P
Sbjct: 34  PEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTV-CDSCEDS-TYTQLWNWVP 91

Query: 80  HCESC-RHCNSGLL-VRNCTITANAECACRNGWQC---RDKECTECDPL 123
            C SC   C+S  +  + CT   N  C CR GW C   + + C  C PL
Sbjct: 92  ECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPL 140


>gi|11140823 X-linked ectodysplasin receptor [Homo sapiens]
          Length = 297

 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 39/107 (36%), Positives = 43/107 (40%), Gaps = 15/107 (14%)

Query: 27  CPERHYWAQGKLC--CQMCEPGTFLVKDCDQHRKA-AQCDPCIP-GVSFSPDHHTRPHCE 82
           C E  YW Q   C  CQ C PG  L KDC       A C  C P     S  HH    C 
Sbjct: 3   CQENEYWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHRCQSCI 62

Query: 83  SCRHCNSGLLVRNCTITANAECA---------CRNGWQCRDKECTEC 120
           +C   N    V NCT T+NA C           R G   +D+EC  C
Sbjct: 63  TCAVINRVQKV-NCTATSNAVCGDCLPRFYRKTRIG-GLQDQECIPC 107


>gi|4507565 tumor necrosis factor receptor superfamily, member 11a
           precursor [Homo sapiens]
          Length = 616

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 36/122 (29%), Positives = 52/122 (42%), Gaps = 11/122 (9%)

Query: 9   LCVLGTLVGLSATPAPKSCPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPG 68
           LC L   + ++   AP    E+HY   G+ CC  CEPG ++   C     +  C PC P 
Sbjct: 17  LCALLARLQVALQIAPPCTSEKHYEHLGR-CCNKCEPGKYMSSKCTTTSDSV-CLPCGPD 74

Query: 69  VSFSPDHHTRPHCESCRHCNSG---LLVRNCTITANAECACRNGWQ-CRDKEC----TEC 120
             +    +    C   + C++G   + V     T    CAC  G+   +D EC    TEC
Sbjct: 75  -EYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHWSQDCECCRRNTEC 133

Query: 121 DP 122
            P
Sbjct: 134 AP 135


>gi|148743793 osteoprotegerin precursor [Homo sapiens]
          Length = 401

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 4/75 (5%)

Query: 37  KLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCNSGL--LVR 94
           +L C  C PGT+L + C    K   C PC P   ++   HT   C  C      L  + +
Sbjct: 38  QLLCDKCPPGTYLKQHCTAKWKTV-CAPC-PDHYYTDSWHTSDECLYCSPVCKELQYVKQ 95

Query: 95  NCTITANAECACRNG 109
            C  T N  C C+ G
Sbjct: 96  ECNRTHNRVCECKEG 110


>gi|21264602 laminin alpha 5 [Homo sapiens]
          Length = 3695

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 31/115 (26%), Positives = 44/115 (38%), Gaps = 20/115 (17%)

Query: 16  VGLSATPAPKSCPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAA--------QCDPCIP 67
           VG       +  P   ++   +LC   C P   L + CD+  +           CD C P
Sbjct: 564 VGFEGATCDRCAPGYFHFPLCQLCG--CSPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRP 621

Query: 68  GVSFSPDHHTRPHCESCRHCNSGLLVRNCTITANAECACRNGWQCRDKECTECDP 122
           G      +H  P+C++C     G L + C   A   C CR G+      C EC P
Sbjct: 622 G------YHGFPNCQACTCDPRGALDQLC--GAGGLCRCRPGY--TGTACQECSP 666



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 29/92 (31%), Positives = 36/92 (39%), Gaps = 16/92 (17%)

Query: 52  DCDQHRKAAQCDPCIPGVSFSPDHH-TRPH-CESCRHCNSGLLVRNCTITANAECACR-- 107
           DC  H     C+ C+PG   SP+H    PH C  C +C S      C       C CR  
Sbjct: 395 DCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRC-NCESDFTDGTCE-DLTGRCYCRPN 452

Query: 108 -NGWQCRDKECTE-------CDPLPNPSLTAR 131
            +G +C    C E       C P P+ S   R
Sbjct: 453 FSGERC--DVCAEGFTGFPSCYPTPSSSNDTR 482



 Score = 37.4 bits (85), Expect = 0.013
 Identities = 27/98 (27%), Positives = 38/98 (38%), Gaps = 9/98 (9%)

Query: 43   CEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESC---RHCNSGLLVRNCTIT 99
            C PG+ +  DC  + + A C+ C  G   S D  + P C SC       S      C + 
Sbjct: 1873 CLPGSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAP-CVSCPCPLSVPSNNFAEGCVLR 1931

Query: 100  -ANAECACRNGWQCRDKECTECDP--LPNPSLTARSSQ 134
                +C C+ G+      C  C P    NP +   S Q
Sbjct: 1932 GGRTQCLCKPGY--AGASCERCAPGFFGNPLVLGSSCQ 1967



 Score = 31.6 bits (70), Expect = 0.72
 Identities = 24/100 (24%), Positives = 34/100 (34%), Gaps = 20/100 (20%)

Query: 43   CEPGTFLVKDCDQHRKAAQCDPCIPGV---SFSPDHHTRPHCESCRH-----------CN 88
            C+P T   + C +H    +C+ C PG    +  P + TR  C  C             C 
Sbjct: 1984 CDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHCLCK 2043

Query: 89   SGLLVRNCTITANAECACRNGWQCRDKEC------TECDP 122
            +G+  R C               CR   C      +EC P
Sbjct: 2044 AGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHP 2083



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 27/98 (27%), Positives = 36/98 (36%), Gaps = 11/98 (11%)

Query: 26  SCPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCR 85
           SC   H  A+G L    C+P +     C       +CD C+PG       +  P+CE+  
Sbjct: 673 SCVPCHCSAEGSLHAA-CDPRSGQCS-CRPRVTGLRCDTCVPGA------YNFPYCEAGS 724

Query: 86  HCNSGLL-VRNCTITANAECACRNGWQCRDKECTECDP 122
              +GL  V      A   C CR         C  C P
Sbjct: 725 CHPAGLAPVDPALPEAQVPCMCRA--HVEGPSCDRCKP 760



 Score = 29.6 bits (65), Expect = 2.8
 Identities = 21/70 (30%), Positives = 26/70 (37%), Gaps = 19/70 (27%)

Query: 32   YWAQGKLCCQMCE-PGTFLVKDCDQHRKAAQCDPCIPG-------------VSFSPDHHT 77
            YW   +  C+ C+ PG      CD H     C P + G             V   P  H+
Sbjct: 2106 YWGLPEQGCRRCQCPGG----RCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHS 2161

Query: 78   RPHCESCRHC 87
              HCE C HC
Sbjct: 2162 I-HCEVCDHC 2170



 Score = 28.5 bits (62), Expect = 6.1
 Identities = 22/74 (29%), Positives = 26/74 (35%), Gaps = 16/74 (21%)

Query: 40   CQMCEPGTF-----LVKDC---------DQHRKAAQCDPCIPGVSFSPDHHTRPHCESCR 85
            C+ C PG F     L   C         D +   + CDP          H T P CE C 
Sbjct: 1948 CERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICA 2007

Query: 86   --HCNSGLLVRNCT 97
                 + LL  NCT
Sbjct: 2008 PGFYGNALLPGNCT 2021


>gi|22547121 tumor necrosis factor receptor superfamily, member 10c
           precursor [Homo sapiens]
          Length = 259

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 19/68 (27%), Positives = 32/68 (47%), Gaps = 4/68 (5%)

Query: 62  CDPCIPGVSFSPDHHTRPHCESCRHCNSGLLVR-NCTITANAECACRNGW---QCRDKEC 117
           C+PC  GV ++   +  P C  C  C S    + +CT+T +  C C+ G    +   + C
Sbjct: 66  CNPCTEGVDYTNASNNEPSCFPCTVCKSDQKHKSSCTMTRDTVCQCKEGTFRNENSPEMC 125

Query: 118 TECDPLPN 125
            +C   P+
Sbjct: 126 RKCSRCPS 133


>gi|22547108 tumor necrosis factor receptor superfamily, member 10d
           precursor [Homo sapiens]
          Length = 386

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 20/59 (33%), Positives = 28/59 (47%), Gaps = 2/59 (3%)

Query: 62  CDPCIPGVSFSPDHHTRPHCESCRHCNSGLLVR-NCTITANAECACRNGWQCRDKECTE 119
           C+PC  GV ++   +  P C  C  C SG   + +CT T +  C C  G   +DK   E
Sbjct: 96  CNPCTEGVDYTIASNNLPSCLLCTVCKSGQTNKSSCTTTRDTVCQCEKG-SFQDKNSPE 153


>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
          Length = 1044

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 29/100 (29%), Positives = 35/100 (35%), Gaps = 30/100 (30%)

Query: 36  GKLCCQMCEPGTF---LVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCNSGLL 92
           G +C Q C PGTF     +DC  H    QCD            H    C    HC +G +
Sbjct: 255 GAVCAQPCPPGTFGQNCSQDCPCHH-GGQCD------------HVTGQC----HCTAGYM 297

Query: 93  VRNCT---------ITANAECACRNGWQCRDKE-CTECDP 122
              C             +  C C NG QC       EC+P
Sbjct: 298 GDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEP 337



 Score = 37.0 bits (84), Expect = 0.017
 Identities = 37/117 (31%), Positives = 48/117 (41%), Gaps = 20/117 (17%)

Query: 17  GLSATPAPKSCPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPG----VSFS 72
           G S     +SCP  +Y    +L C  C+ G     DC        C P   G    VS +
Sbjct: 384 GWSGHHCNESCPVGYYGDGCQLPCT-CQNGA----DCHSITGGCTCAPGFMGEVCAVSCA 438

Query: 73  PDHHTRPHCESCRHCNSGLLVRNCTITANAECACRNGWQCRDKECTECDPLPNPSLT 129
              +  P+C S   CN+G     C+   +  C C+ GWQ  D  CT    LP PS T
Sbjct: 439 AGTYG-PNCSSICSCNNG---GTCS-PVDGSCTCKEGWQGLD--CT----LPCPSGT 484


>gi|4507483 thrombomodulin precursor [Homo sapiens]
          Length = 575

 Score = 38.1 bits (87), Expect = 0.008
 Identities = 52/239 (21%), Positives = 82/239 (34%), Gaps = 41/239 (17%)

Query: 24  PKSCPERHYWAQGKLCCQMCEPGTFLVKD--------CDQHRKAAQCDP-------CIPG 68
           P  CP+R    QG   C  C P   LV          C +     QC P       C+  
Sbjct: 333 PSPCPQRCVNTQGGFECH-CYPNYDLVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCA 391

Query: 69  VSFSPDHHTRPHCESCRHCNSGLLVRNCTITANAECACRNGWQCRDK-ECTECDPLPNPS 127
             F+P  H    C+    CN      +C     A C C  G+   D   CT+ D   N  
Sbjct: 392 EGFAPIPHEPHRCQM--FCNQTACPADCDPNTQASCECPEGYILDDGFICTDIDECENGG 449

Query: 128 LTARSSQALSPHPQPTHLPYVSEML---EARTAGHMQTLADFRQLPARTLSTHWPPQRSL 184
             +             +LP   E +   ++  A H+ T  D  ++      +  PP    
Sbjct: 450 FCSGVCH---------NLPGTFECICGPDSALARHIGTDCDSGKVDGGDSGSGEPPPSPT 500

Query: 185 CSSDFI--RILVIFSGMFLVFTLAG--------ALFLHQRRKYRSNKGESPVEPAEPCR 233
             S      + ++ SG+ +  ++A         AL  H R+K  + + +   + A P +
Sbjct: 501 PGSTLTPPAVGLVHSGLLIGISIASLCLVVALLALLCHLRKKQGAARAKMEYKCAAPSK 559


>gi|68348711 tumor necrosis factor receptor superfamily, member 8
           isoform 1 precursor [Homo sapiens]
          Length = 595

 Score = 37.7 bits (86), Expect = 0.010
 Identities = 26/97 (26%), Positives = 35/97 (36%), Gaps = 11/97 (11%)

Query: 28  PERHYWAQGKLCCQMCEPGTFLVKDCDQHRK--AAQCDPCIPGVSFSPDHHTRPHCESCR 85
           P  +Y    + CC  C  G F  + C Q       QC+P      +  D   R  C +C 
Sbjct: 33  PSHYYDKAVRRCCYRCPMGLFPTQQCPQRPTDCRKQCEP-----DYYLDEADR--CTACV 85

Query: 86  HCNSGLLVRN--CTITANAECACRNGWQCRDKECTEC 120
            C+   LV    C   ++  C CR G  C       C
Sbjct: 86  TCSRDDLVEKTPCAWNSSRVCECRPGMFCSTSAVNSC 122


>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
          Length = 1541

 Score = 37.4 bits (85), Expect = 0.013
 Identities = 36/127 (28%), Positives = 49/127 (38%), Gaps = 27/127 (21%)

Query: 36   GKLCCQMCEPGTF-----LVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCNSG 90
            G  C + CEPG+F        DCD     A CDP + G+   P   +   C     C  G
Sbjct: 1414 GHFCERGCEPGSFGEGCHQRCDCD---GGAPCDP-VTGLCLCPPGRSGATCN--LDCRRG 1467

Query: 91   LLVRNCTI-----------TANAECACRNGWQCRDKECTECDPL---PNPSLTARSSQAL 136
                +CT+             + +C C +G+      C E  PL    NPSL   S+  L
Sbjct: 1468 QFGPSCTLHCDCGGGADCDPVSGQCHCVDGYM--GPTCREGGPLRLPENPSLAQGSAGTL 1525

Query: 137  SPHPQPT 143
                +PT
Sbjct: 1526 PASSRPT 1532



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 21/96 (21%)

Query: 17   GLSATPAPKSCPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHH 76
            G   T    +CP+  +   G  C  +C  G           + A CDP + G    P   
Sbjct: 1239 GFLGTDCNLTCPQGRF---GPNCTHVCGCG-----------QGAACDP-VTGTCLCPPGR 1283

Query: 77   TRPHCESCRHCNSGLLVRNCTITANAECACRNGWQC 112
                CE  R C        C  T    C+CRNG  C
Sbjct: 1284 AGVRCE--RGCPQNRFGVGCEHT----CSCRNGGLC 1313



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 27/112 (24%), Positives = 36/112 (32%), Gaps = 41/112 (36%)

Query: 17  GLSATPAPKSCPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAAQCDP------CIPGVS 70
           G +       CPE  +    +  C  C           QH  AA+CDP      C+PG  
Sbjct: 763 GRTGEDCEADCPEGRWGLGCQEICPAC-----------QH--AARCDPETGACLCLPGFV 809

Query: 71  ------------FSPDHHTRPHCESCRHCNSGLLVRNCTITANAECACRNGW 110
                       + P   TR  C +  HC+           A   C+C  GW
Sbjct: 810 GSRCQDVCPAGWYGPSCQTRCSCANDGHCH----------PATGHCSCAPGW 851


>gi|9506545 delta-like 4 protein precursor [Homo sapiens]
          Length = 685

 Score = 36.6 bits (83), Expect = 0.023
 Identities = 31/101 (30%), Positives = 41/101 (40%), Gaps = 25/101 (24%)

Query: 27  CPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAAQCDP-----CIPGVSFSPDHHTRPHC 81
           C + +Y   G  C ++C       K  + H     C P     C+PG        T  +C
Sbjct: 175 CSDNYY---GDNCSRLC-------KKRNDHFGHYVCQPDGNLSCLPG-------WTGEYC 217

Query: 82  ESCRHCNSGLLVRNCTITANAECACRNGWQCRDKECTECDP 122
           +    C SG   +N   +  AEC CR GWQ R   C EC P
Sbjct: 218 QQ-PICLSGCHEQNGYCSKPAECLCRPGWQGR--LCNECIP 255



 Score = 29.6 bits (65), Expect = 2.8
 Identities = 32/114 (28%), Positives = 41/114 (35%), Gaps = 27/114 (23%)

Query: 24  PKSCPERHYWAQGKLCCQM-----CEPGTFLVK---DCDQHRKAAQCD----------PC 65
           P  C  R  W QG+LC +      C  GT        CD+      CD          PC
Sbjct: 236 PAECLCRPGW-QGRLCNECIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPC 294

Query: 66  IPGVSFSPDHHTRPHCESCRHCNSGLLVRNCTITANAEC---ACRNGWQCRDKE 116
             G + S        C     C  G    +C +  + EC    CRNG  C+D+E
Sbjct: 295 KNGATCSNSGQRSYTCT----CRPGYTGVDCELELS-ECDSNPCRNGGSCKDQE 343


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.135    0.468 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,179,945
Number of Sequences: 37866
Number of extensions: 685570
Number of successful extensions: 2653
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 115
Number of HSP's that attempted gapping in prelim test: 2452
Number of HSP's gapped (non-prelim): 290
length of query: 260
length of database: 18,247,518
effective HSP length: 100
effective length of query: 160
effective length of database: 14,460,918
effective search space: 2313746880
effective search space used: 2313746880
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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