Guide to the Human Genome
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Name: DLL4 Sequence: fasta or formatted (685aa) NCBI GI: 9506545
Description:

delta-like 4 protein precursor

Referenced in:

Notch Pathway

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.8         40           3
 C cysteine            9.3         64           1
 D aspartate           4.8         33           2
 E glutamate           4.8         33           2
 F phenylalanine       3.4         23           2
 G glycine             9.8         67           3
 H histidine           2.6         18           2
 I isoleucine          2.2         15           2
 K lysine              2.8         19           2
 L leucine             8.8         60           4
 M methionine          1.0          7           1
 N asparagine          5.5         38           2
 P proline             6.9         47           2
 Q glutamine           4.1         28           2
 R arginine            6.3         43           2
 S serine              8.0         55           2
 T threonine           5.1         35           1
 V valine              4.5         31           2
 W tryptophan          1.5         10           1
 Y tyrosine            2.8         19           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   delta-like 4 protein precursor 
DLL1                  0.462   delta-like 1 
JAG2                  0.308   jagged 2 isoform a precursor 
JAG1                  0.304   jagged 1 precursor 
JAG2                  0.298   jagged 2 isoform b precursor 
DLL3                  0.199   delta-like 3 protein isoform 1 precursor 
DLL3                  0.199   delta-like 3 protein isoform 2 precursor 
NOTCH1                0.160   notch1 preproprotein 
NOTCH2                0.158   notch 2 preproprotein 
EYS                   0.147   eyes shut homolog isoform 1 
NOTCH3                0.145   Notch homolog 3 
NOTCH4                0.143   notch4 preproprotein 
CRB1                  0.140   crumbs homolog 1 precursor 
DNER                  0.135   delta-notch-like EGF repeat-containing transmembran...
CRB2                  0.132   crumbs homolog 2 
SVEP1                 0.130   polydom 
DLK2                  0.130   EGF-like-domain, multiple 9 
DLK2                  0.130   EGF-like-domain, multiple 9 
DLK1                  0.129   delta-like 1 homolog 
SNED1                 0.125   6720455I24Rik homolog 
SLIT2                 0.116   slit homolog 2 
SLIT3                 0.112   slit homolog 3 
SLIT1                 0.108   slit homolog 1 
VWDE                  0.091   von Willebrand factor D and EGF domains 
MEGF6                 0.091   EGF-like-domain, multiple 3 
MEGF11                0.087   multiple EGF-like-domains 11 
MEGF10                0.084   multiple EGF-like-domains 10 
PEAR1                 0.084   platelet endothelial aggregation receptor 1 
NOTCH2NL              0.081   Notch homolog 2 N-terminal like protein 
TNC                   0.076   tenascin C precursor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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