Guide to the Human Genome
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Search of human proteins with 4507585

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507585 tumor necrosis factor receptor superfamily, member
6b [Homo sapiens]
         (300 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14790170 tumor necrosis factor receptor superfamily, member 6...   634   0.0  
gi|4507585 tumor necrosis factor receptor superfamily, member 6b...   634   0.0  
gi|148743793 osteoprotegerin precursor [Homo sapiens]                 172   3e-43
gi|4507577 tumor necrosis factor receptor 2 precursor [Homo sapi...   129   4e-30
gi|7657039 tumor necrosis factor receptor superfamily, member 21...   115   6e-26
gi|4505039 lymphotoxin beta receptor [Homo sapiens]                   115   6e-26
gi|23200041 tumor necrosis factor receptor superfamily, member 1...    95   9e-20
gi|4507565 tumor necrosis factor receptor superfamily, member 11...    92   4e-19
gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]             83   3e-16
gi|4507579 tumor necrosis factor receptor superfamily, member 4 ...    79   4e-15
gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]            73   3e-13
gi|68348711 tumor necrosis factor receptor superfamily, member 8...    69   5e-12
gi|5730095 tumor necrosis factor receptor superfamily, member 9 ...    64   1e-10
gi|4505393 nerve growth factor receptor precursor [Homo sapiens]       64   2e-10
gi|23238200 RELT tumor necrosis factor receptor precursor [Homo ...    58   1e-08
gi|21361873 RELT tumor necrosis factor receptor precursor [Homo ...    58   1e-08
gi|4759246 tumor necrosis factor receptor superfamily, member 18...    54   2e-07
gi|23238197 tumor necrosis factor receptor superfamily, member 1...    54   2e-07
gi|23510423 tumor necrosis factor receptor superfamily, member 6...    53   4e-07
gi|23510421 tumor necrosis factor receptor superfamily, member 6...    53   4e-07
gi|4507583 tumor necrosis factor receptor superfamily, member 6 ...    53   4e-07
gi|4507587 tumor necrosis factor receptor superfamily, member 7 ...    52   5e-07
gi|21361086 tumor necrosis factor receptor superfamily, member 1...    51   1e-06
gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapi...    44   2e-04
gi|84490388 R-spondin1 [Homo sapiens]                                  43   3e-04
gi|11140823 X-linked ectodysplasin receptor [Homo sapiens]             43   3e-04
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]               42   5e-04
gi|134244285 Notch homolog 3 [Homo sapiens]                            42   9e-04
gi|239757286 PREDICTED: similar to Fc fragment of IgG binding pr...    41   0.001
gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ...    41   0.001

>gi|14790170 tumor necrosis factor receptor superfamily, member 6b
           [Homo sapiens]
          Length = 300

 Score =  634 bits (1634), Expect = 0.0
 Identities = 300/300 (100%), Positives = 300/300 (100%)

Query: 1   MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQR 60
           MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQR
Sbjct: 1   MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQR 60

Query: 61  PCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFF 120
           PCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFF
Sbjct: 61  PCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFF 120

Query: 121 AHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLA 180
           AHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLA
Sbjct: 121 AHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLA 180

Query: 181 LNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISIKRLQRLLQALEAPE 240
           LNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISIKRLQRLLQALEAPE
Sbjct: 181 LNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISIKRLQRLLQALEAPE 240

Query: 241 GWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMPGLERSVRERFLPVH 300
           GWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMPGLERSVRERFLPVH
Sbjct: 241 GWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMPGLERSVRERFLPVH 300


>gi|4507585 tumor necrosis factor receptor superfamily, member 6b
           [Homo sapiens]
          Length = 300

 Score =  634 bits (1634), Expect = 0.0
 Identities = 300/300 (100%), Positives = 300/300 (100%)

Query: 1   MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQR 60
           MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQR
Sbjct: 1   MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQR 60

Query: 61  PCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFF 120
           PCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFF
Sbjct: 61  PCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFF 120

Query: 121 AHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLA 180
           AHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLA
Sbjct: 121 AHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLA 180

Query: 181 LNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISIKRLQRLLQALEAPE 240
           LNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISIKRLQRLLQALEAPE
Sbjct: 181 LNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISIKRLQRLLQALEAPE 240

Query: 241 GWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMPGLERSVRERFLPVH 300
           GWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMPGLERSVRERFLPVH
Sbjct: 241 GWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMPGLERSVRERFLPVH 300


>gi|148743793 osteoprotegerin precursor [Homo sapiens]
          Length = 401

 Score =  172 bits (436), Expect = 3e-43
 Identities = 77/187 (41%), Positives = 108/187 (57%), Gaps = 5/187 (2%)

Query: 34  PTYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNV 93
           P Y   D ET  +L+C +CPPGT++++ C     T C PCP  +YT  W+  + C YC+ 
Sbjct: 26  PKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDHYYTDSWHTSDECLYCSP 85

Query: 94  LCGEREEEARACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPC 153
           +C E +   + C+ THNR C C+ G +    FCL+H SCPPG GV+  GTP +NT C+ C
Sbjct: 86  VCKELQYVKQECNRTHNRVCECKEGRYLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRC 145

Query: 154 PPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEE--C 211
           P G FS  +SS   C+ H NC+  GL L   G+++HD +   C+G   ST+  G +   C
Sbjct: 146 PDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNATHDNI---CSGNSESTQKCGIDVTLC 202

Query: 212 ERAVIDF 218
           E A   F
Sbjct: 203 EEAFFRF 209


>gi|4507577 tumor necrosis factor receptor 2 precursor [Homo
           sapiens]
          Length = 461

 Score =  129 bits (323), Expect = 4e-30
 Identities = 72/210 (34%), Positives = 102/210 (48%), Gaps = 18/210 (8%)

Query: 8   GLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGER---LVCAQCPPGTFVQRPCRR 64
           GL L     ALPA +   A    A  P    R  E  ++   + C++C PG   +  C +
Sbjct: 13  GLELWAAAHALPAQV---AFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTK 69

Query: 65  DSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAG 124
            S T C  C    YTQ WN++  C  C   C   + E +AC    NR C CR G++    
Sbjct: 70  TSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALS 129

Query: 125 ------FCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALG 178
                  C     C PG GV  PGT + +  C+PC PGTFS ++SS++ C+PH+ C  + 
Sbjct: 130 KQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVA 189

Query: 179 LALNVPGSSSHDTLCTSCTGFPLSTRVPGA 208
               +PG++S D +CTS +  P  +  PGA
Sbjct: 190 ----IPGNASMDAVCTSTS--PTRSMAPGA 213


>gi|7657039 tumor necrosis factor receptor superfamily, member 21
           precursor [Homo sapiens]
          Length = 655

 Score =  115 bits (287), Expect = 6e-26
 Identities = 58/169 (34%), Positives = 81/169 (47%)

Query: 35  TYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVL 94
           TY   D  TG+ L C +CP GT+V   C   S   C  CP   +T+  N +E+C  C+  
Sbjct: 53  TYRHVDRATGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQP 112

Query: 95  CGEREEEARACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCP 154
           C     E   C A  +R C C  G F     C  H  CP G GV   GT +++ +C+ C 
Sbjct: 113 CPWPMIEKLPCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCA 172

Query: 155 PGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLST 203
            GTFS   SS  +C+ + +C +  L +  PG+   D +C +   F  ST
Sbjct: 173 RGTFSDVPSSVMKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSST 221


>gi|4505039 lymphotoxin beta receptor [Homo sapiens]
          Length = 435

 Score =  115 bits (287), Expect = 6e-26
 Identities = 86/276 (31%), Positives = 117/276 (42%), Gaps = 34/276 (12%)

Query: 3   ALEGPGLSLLCLVLALPALLPVPAVRGV----AETPTYPWRDAETGE---RLVCAQCPPG 55
           A   PGL+   LVL L  LL     + V    +E  T   ++ E  E   R+ C++CPPG
Sbjct: 6   ATSAPGLAWGPLVLGLFGLLAASQPQAVPPYASENQTCRDQEKEYYEPQHRICCSRCPPG 65

Query: 56  TFVQRPCRRDSPTTCGPCPPRHYTQFWNYL---ERCRYCNVLCGEREEEARACHATHNRA 112
           T+V   C R   T C  C    Y + WNYL   + CR C+ + G   EE   C +     
Sbjct: 66  TYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMG--LEEIAPCTSKRKTQ 123

Query: 113 CRCRTGFFAHA-----GFCLEHASCPPGA-GVIAPGTPSQNTQCQPCPPGTFSASSSSSE 166
           CRC+ G F  A       C   + CPPG    +       N  C PC  G F  +SS S 
Sbjct: 124 CRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSSPSA 183

Query: 167 QCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDIS- 225
           +CQPH  C   GL    PG++  DT C +    PL   + G       ++    F  ++ 
Sbjct: 184 RCQPHTRCENQGLVEAAPGTAQSDTTCKNPLE-PLPPEMSGTMLMLAVLLPLAFFLLLAT 242

Query: 226 ------------IKRLQRLLQALEAPEGWGPTPRAG 249
                        ++L  LL+    P+G GP P AG
Sbjct: 243 VFSCIWKSHPSLCRKLGSLLK--RRPQGEGPNPVAG 276


>gi|23200041 tumor necrosis factor receptor superfamily, member 14
           precursor [Homo sapiens]
          Length = 283

 Score = 94.7 bits (234), Expect = 9e-20
 Identities = 55/149 (36%), Positives = 68/149 (45%), Gaps = 10/149 (6%)

Query: 49  CAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGERE--EEARACH 106
           C +C PG  V+  C   + T C PCPP  Y    N L +C  C  +C        +R C 
Sbjct: 54  CPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQ-MCDPAMGLRASRNCS 112

Query: 107 ATHNRACRCRTGFFA------HAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSA 160
            T N  C C  G F       H   C  +A+  PG  V   GT SQ+T CQ CPPGTFS 
Sbjct: 113 RTENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFS- 171

Query: 161 SSSSSEQCQPHRNCTALGLALNVPGSSSH 189
            + + E+CQ    C+ L        SSSH
Sbjct: 172 PNGTLEECQHQTKCSWLVTKAGAGTSSSH 200


>gi|4507565 tumor necrosis factor receptor superfamily, member 11a
           precursor [Homo sapiens]
          Length = 616

 Score = 92.4 bits (228), Expect = 4e-19
 Identities = 48/150 (32%), Positives = 72/150 (48%), Gaps = 3/150 (2%)

Query: 49  CAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVL-CGEREEEARACHA 107
           C +C PG ++   C   S + C PC P  Y   WN  ++C    V   G+      A ++
Sbjct: 47  CNKCEPGKYMSSKCTTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNS 106

Query: 108 THNRACRCRTGFF--AHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSS 165
           T  R C C  G+        C  +  C PG G   P   +++T C+PC  G FS + SS+
Sbjct: 107 TTPRRCACTAGYHWSQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSST 166

Query: 166 EQCQPHRNCTALGLALNVPGSSSHDTLCTS 195
           ++C+P  NCT LG  +   G+   D +C+S
Sbjct: 167 DKCRPWTNCTFLGKRVEHHGTEKSDAVCSS 196



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 9/94 (9%)

Query: 120 FAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNC-TALG 178
           + H G C     C PG  + +  T + ++ C PC P  +  S +  ++C  H+ C T   
Sbjct: 40  YEHLGRCCN--KCEPGKYMSSKCTTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKA 97

Query: 179 LALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECE 212
           L   V G+S+    C    G+  S      ++CE
Sbjct: 98  LVAVVAGNSTTPRRCACTAGYHWS------QDCE 125


>gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]
          Length = 277

 Score = 83.2 bits (204), Expect = 3e-16
 Identities = 46/151 (30%), Positives = 67/151 (44%), Gaps = 8/151 (5%)

Query: 49  CAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERC---RYCNVLCGEREEEARAC 105
           C+ C PG  +   C   + T C PC    +   WN    C   +YC+   G R ++    
Sbjct: 38  CSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCDPNLGLRVQQKGTS 97

Query: 106 HATHNRACRCRTGFFAHAGFC---LEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASS 162
               +  C C  G+   +  C   + H SC PG GV    T   +T C+PCP G FS  S
Sbjct: 98  ET--DTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVS 155

Query: 163 SSSEQCQPHRNCTALGLALNVPGSSSHDTLC 193
           S+ E+C P  +C    L +   G++  D +C
Sbjct: 156 SAFEKCHPWTSCETKDLVVQQAGTNKTDVVC 186



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 33/127 (25%), Positives = 55/127 (43%), Gaps = 10/127 (7%)

Query: 104 ACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSS 163
           A H     ACR +  +  ++  C   + C PG  +++  T    T+C PC    F  + +
Sbjct: 17  AVHPEPPTACREKQ-YLINSQCC---SLCQPGQKLVSDCTEFTETECLPCGESEFLDTWN 72

Query: 164 SSEQCQPHRNCTA-LGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQ 222
               C  H+ C   LGL +   G+S  DT+CT   G+  +     +E CE  V+      
Sbjct: 73  RETHCHQHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCT-----SEACESCVLHRSCSP 127

Query: 223 DISIKRL 229
              +K++
Sbjct: 128 GFGVKQI 134


>gi|4507579 tumor necrosis factor receptor superfamily, member 4
           precursor [Homo sapiens]
          Length = 277

 Score = 79.3 bits (194), Expect = 4e-15
 Identities = 59/190 (31%), Positives = 75/190 (39%), Gaps = 36/190 (18%)

Query: 6   GPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQRPCRRD 65
           GP  +LL L L L  +  +  V       TYP  D        C +C PG  +   C R 
Sbjct: 11  GPCAALLLLGLGLSTVTGLHCVGD-----TYPSNDR------CCHECRPGNGMVSRCSRS 59

Query: 66  SPTTCGPCPPRHYTQFWNY--LERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHA 123
             T C PC P  Y    +    + C +CN+  G   E  + C AT +  CRCR G     
Sbjct: 60  QNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSG--SERKQLCTATQDTVCRCRAG----- 112

Query: 124 GFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNV 183
                  S  PG              C PCPPG F  S   ++ C+P  NCT  G     
Sbjct: 113 --TQPLDSYKPG------------VDCAPCPPGHF--SPGDNQACKPWTNCTLAGKHTLQ 156

Query: 184 PGSSSHDTLC 193
           P S+S D +C
Sbjct: 157 PASNSSDAIC 166



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 28/80 (35%), Positives = 41/80 (51%), Gaps = 3/80 (3%)

Query: 132 CPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCT-ALGLALNVPGSSSHD 190
           C PG G+++  + SQNT C+PC PG F     SS+ C+P   C    G       +++ D
Sbjct: 46  CRPGNGMVSRCSRSQNTVCRPCGPG-FYNDVVSSKPCKPCTWCNLRSGSERKQLCTATQD 104

Query: 191 TLCTSCTGF-PLSTRVPGAE 209
           T+C    G  PL +  PG +
Sbjct: 105 TVCRCRAGTQPLDSYKPGVD 124


>gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]
          Length = 203

 Score = 72.8 bits (177), Expect = 3e-13
 Identities = 41/128 (32%), Positives = 57/128 (44%), Gaps = 8/128 (6%)

Query: 49  CAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERC---RYCNVLCGEREEEARAC 105
           C+ C PG  +   C   + T C PC    +   WN    C   +YC+   G R ++    
Sbjct: 38  CSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCDPNLGLRVQQKGTS 97

Query: 106 HATHNRACRCRTGFFAHAGFC---LEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASS 162
               +  C C  G+   +  C   + H SC PG GV    T   +T C+PCP G FS  S
Sbjct: 98  ET--DTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVS 155

Query: 163 SSSEQCQP 170
           S+ E+C P
Sbjct: 156 SAFEKCHP 163



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 33/127 (25%), Positives = 55/127 (43%), Gaps = 10/127 (7%)

Query: 104 ACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSS 163
           A H     ACR +  +  ++  C   + C PG  +++  T    T+C PC    F  + +
Sbjct: 17  AVHPEPPTACREKQ-YLINSQCC---SLCQPGQKLVSDCTEFTETECLPCGESEFLDTWN 72

Query: 164 SSEQCQPHRNCTA-LGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQ 222
               C  H+ C   LGL +   G+S  DT+CT   G+  +     +E CE  V+      
Sbjct: 73  RETHCHQHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCT-----SEACESCVLHRSCSP 127

Query: 223 DISIKRL 229
              +K++
Sbjct: 128 GFGVKQI 134



 Score = 28.5 bits (62), Expect = 7.6
 Identities = 16/62 (25%), Positives = 23/62 (37%)

Query: 52  CPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNR 111
           C PG  V++     S T C PCP   ++   +  E+C       G  E      H   + 
Sbjct: 125 CSPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHPWTRSPGSAESPGGDPHHLRDP 184

Query: 112 AC 113
            C
Sbjct: 185 VC 186


>gi|68348711 tumor necrosis factor receptor superfamily, member 8
           isoform 1 precursor [Homo sapiens]
          Length = 595

 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 43/131 (32%), Positives = 57/131 (43%), Gaps = 12/131 (9%)

Query: 46  RLVCAQCPPGTFVQRPCRRDSPTTCGP-CPPRHYTQFWNYLERCRYCNVLCGEREEEARA 104
           R  C +CP G F  + C +  PT C   C P +Y    +  +RC  C     +   E   
Sbjct: 42  RRCCYRCPMGLFPTQQCPQ-RPTDCRKQCEPDYYL---DEADRCTACVTCSRDDLVEKTP 97

Query: 105 CHATHNRACRCRTGFFAHAGF------CLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTF 158
           C    +R C CR G F           C  H+ CP G  V  PGT  +NT C+P  PG  
Sbjct: 98  CAWNSSRVCECRPGMFCSTSAVNSCARCFFHSVCPAGMIVKFPGTAQKNTVCEPASPGV- 156

Query: 159 SASSSSSEQCQ 169
           S + +S E C+
Sbjct: 157 SPACASPENCK 167



 Score = 32.3 bits (72), Expect = 0.52
 Identities = 21/81 (25%), Positives = 26/81 (32%), Gaps = 3/81 (3%)

Query: 54  PGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRAC 113
           PG    +PC   S      C P +Y    +   RC  C     +   E   C    +R C
Sbjct: 225 PGLSPTQPCPEGSGDCRKQCEPDYYL---DEAGRCTACVSCSRDDLVEKTPCAWNSSRTC 281

Query: 114 RCRTGFFAHAGFCLEHASCPP 134
            CR G           A C P
Sbjct: 282 ECRPGMICATSATNSRARCVP 302


>gi|5730095 tumor necrosis factor receptor superfamily, member 9
           precursor [Homo sapiens]
          Length = 255

 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 43/148 (29%), Positives = 61/148 (41%), Gaps = 20/148 (13%)

Query: 49  CAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNY--LERCRYCNVLCGEREEEARACH 106
           C+ CP GTF    C  +    C PCPP  ++        + CR C  +   R+E    C 
Sbjct: 28  CSNCPAGTF----CDNNRNQICSPCPPNSFSSAGGQRTCDICRQCKGVFRTRKE----CS 79

Query: 107 ATHNRACRCRTGFFA-HAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSS 165
           +T N  C C  GF    AG  +    C  G  +   G       C+ C  GTF+      
Sbjct: 80  STSNAECDCTPGFHCLGAGCSMCEQDCKQGQELTKKG-------CKDCCFGTFNDQKRGI 132

Query: 166 EQCQPHRNCTALGLALNVPGSSSHDTLC 193
             C+P  NC+  G ++ V G+   D +C
Sbjct: 133 --CRPWTNCSLDGKSVLVNGTKERDVVC 158



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 6/70 (8%)

Query: 130 ASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSH 189
           ++CP G         ++N  C PCPP +FS S+     C   R C  +        SS+ 
Sbjct: 29  SNCPAGTFC----DNNRNQICSPCPPNSFS-SAGGQRTCDICRQCKGV-FRTRKECSSTS 82

Query: 190 DTLCTSCTGF 199
           +  C    GF
Sbjct: 83  NAECDCTPGF 92


>gi|4505393 nerve growth factor receptor precursor [Homo sapiens]
          Length = 427

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 49/176 (27%), Positives = 74/176 (42%), Gaps = 16/176 (9%)

Query: 2   RALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQRP 61
           RA++GP L LL L+      + +   +    T  Y      +GE   C  C  G  V +P
Sbjct: 8   RAMDGPRLLLLLLLG-----VSLGGAKEACPTGLY----THSGE--CCKACNLGEGVAQP 56

Query: 62  CRRDSPTTCGPCPPR-HYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFF 120
           C  +  T C PC     ++   +  E C+ C    G +   A  C    +  CRC  G++
Sbjct: 57  CGANQ-TVCEPCLDSVTFSDVVSATEPCKPCTECVGLQSMSA-PCVEADDAVCRCAYGYY 114

Query: 121 AH--AGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNC 174
                G C     C  G+G++      QNT C+ CP GT+S  ++  + C P   C
Sbjct: 115 QDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVC 170



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 5/98 (5%)

Query: 115 CRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPG-TFSASSSSSEQCQPHRN 173
           C TG + H+G C +  +C  G GV  P   +Q T C+PC    TFS   S++E C+P   
Sbjct: 32  CPTGLYTHSGECCK--ACNLGEGVAQPCGANQ-TVCEPCLDSVTFSDVVSATEPCKPCTE 88

Query: 174 CTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEEC 211
           C  L  +++ P   + D +C    G+         E C
Sbjct: 89  CVGL-QSMSAPCVEADDAVCRCAYGYYQDETTGRCEAC 125


>gi|23238200 RELT tumor necrosis factor receptor precursor [Homo
           sapiens]
          Length = 430

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 30/65 (46%), Positives = 35/65 (53%), Gaps = 3/65 (4%)

Query: 132 CPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDT 191
           CPPG        P Q T C+PCPPGTFSA+  SS  CQPH  C+         G ++ DT
Sbjct: 32  CPPGEEPDLD--PGQGTLCRPCPPGTFSAAWGSS-PCQPHARCSLWRRLEAQVGMATRDT 88

Query: 192 LCTSC 196
           LC  C
Sbjct: 89  LCGDC 93



 Score = 35.4 bits (80), Expect = 0.062
 Identities = 21/76 (27%), Positives = 29/76 (38%), Gaps = 7/76 (9%)

Query: 11 LLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTC 70
          L C ++ LP  L       + + P     D + G+  +C  CPPGTF        +    
Sbjct: 10 LSCFLMLLPWPLATLTSTTLWQCPPGEEPDLDPGQGTLCRPCPPGTF-------SAAWGS 62

Query: 71 GPCPPRHYTQFWNYLE 86
           PC P      W  LE
Sbjct: 63 SPCQPHARCSLWRRLE 78


>gi|21361873 RELT tumor necrosis factor receptor precursor [Homo
           sapiens]
          Length = 430

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 30/65 (46%), Positives = 35/65 (53%), Gaps = 3/65 (4%)

Query: 132 CPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDT 191
           CPPG        P Q T C+PCPPGTFSA+  SS  CQPH  C+         G ++ DT
Sbjct: 32  CPPGEEPDLD--PGQGTLCRPCPPGTFSAAWGSS-PCQPHARCSLWRRLEAQVGMATRDT 88

Query: 192 LCTSC 196
           LC  C
Sbjct: 89  LCGDC 93



 Score = 35.4 bits (80), Expect = 0.062
 Identities = 21/76 (27%), Positives = 29/76 (38%), Gaps = 7/76 (9%)

Query: 11 LLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTC 70
          L C ++ LP  L       + + P     D + G+  +C  CPPGTF        +    
Sbjct: 10 LSCFLMLLPWPLATLTSTTLWQCPPGEEPDLDPGQGTLCRPCPPGTF-------SAAWGS 62

Query: 71 GPCPPRHYTQFWNYLE 86
           PC P      W  LE
Sbjct: 63 SPCQPHARCSLWRRLE 78


>gi|4759246 tumor necrosis factor receptor superfamily, member 18
           isoform 1 precursor [Homo sapiens]
          Length = 241

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 34/110 (30%), Positives = 42/110 (38%), Gaps = 19/110 (17%)

Query: 101 EARACHATHNRACRCRTG---------------FFAHAGFCL--EHASCPPGAGVIAPGT 143
           +AR C     R CR   G               F      C    H  CPPG GV + G 
Sbjct: 46  DARCCRVHTTRCCRDYPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGK 105

Query: 144 PSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLC 193
            S   QC  C  GTFS        C+P  +CT  G     PG+ +H+ +C
Sbjct: 106 FSFGFQCIDCASGTFSGGHEG--HCKPWTDCTQFGFLTVFPGNKTHNAVC 153


>gi|23238197 tumor necrosis factor receptor superfamily, member 18
           isoform 3 precursor [Homo sapiens]
          Length = 234

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 34/110 (30%), Positives = 42/110 (38%), Gaps = 19/110 (17%)

Query: 101 EARACHATHNRACRCRTG---------------FFAHAGFCL--EHASCPPGAGVIAPGT 143
           +AR C     R CR   G               F      C    H  CPPG GV + G 
Sbjct: 46  DARCCRVHTTRCCRDYPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGK 105

Query: 144 PSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLC 193
            S   QC  C  GTFS        C+P  +CT  G     PG+ +H+ +C
Sbjct: 106 FSFGFQCIDCASGTFSGGHEG--HCKPWTDCTQFGFLTVFPGNKTHNAVC 153


>gi|23510423 tumor necrosis factor receptor superfamily, member 6
           isoform 3 precursor [Homo sapiens]
          Length = 220

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 39/109 (35%), Positives = 50/109 (45%), Gaps = 14/109 (12%)

Query: 52  CPPGTFVQRPC--RRDSPTTCGPCPP-RHYTQFWNYLERCRYCNVLCGERE--EEARACH 106
           CPPG    R C    D P  C PC   + YT   ++  +CR C  LC E    E    C 
Sbjct: 63  CPPGERKARDCTVNGDEPD-CVPCQEGKEYTDKAHFSSKCRRCR-LCDEGHGLEVEINCT 120

Query: 107 ATHNRACRCRTGFFAHAGFCLEHASCPPGA----GVIAPGTPSQNTQCQ 151
            T N  CRC+  FF ++  C EH  C P      G+I   T + NT+C+
Sbjct: 121 RTQNTKCRCKPNFFCNSTVC-EH--CDPCTKCEHGIIKECTLTSNTKCK 166


>gi|23510421 tumor necrosis factor receptor superfamily, member 6
           isoform 2 precursor [Homo sapiens]
          Length = 314

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 39/109 (35%), Positives = 50/109 (45%), Gaps = 14/109 (12%)

Query: 52  CPPGTFVQRPC--RRDSPTTCGPCPP-RHYTQFWNYLERCRYCNVLCGERE--EEARACH 106
           CPPG    R C    D P  C PC   + YT   ++  +CR C  LC E    E    C 
Sbjct: 63  CPPGERKARDCTVNGDEPD-CVPCQEGKEYTDKAHFSSKCRRCR-LCDEGHGLEVEINCT 120

Query: 107 ATHNRACRCRTGFFAHAGFCLEHASCPPGA----GVIAPGTPSQNTQCQ 151
            T N  CRC+  FF ++  C EH  C P      G+I   T + NT+C+
Sbjct: 121 RTQNTKCRCKPNFFCNSTVC-EH--CDPCTKCEHGIIKECTLTSNTKCK 166


>gi|4507583 tumor necrosis factor receptor superfamily, member 6
           isoform 1 precursor [Homo sapiens]
          Length = 335

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 39/109 (35%), Positives = 50/109 (45%), Gaps = 14/109 (12%)

Query: 52  CPPGTFVQRPC--RRDSPTTCGPCPP-RHYTQFWNYLERCRYCNVLCGERE--EEARACH 106
           CPPG    R C    D P  C PC   + YT   ++  +CR C  LC E    E    C 
Sbjct: 63  CPPGERKARDCTVNGDEPD-CVPCQEGKEYTDKAHFSSKCRRCR-LCDEGHGLEVEINCT 120

Query: 107 ATHNRACRCRTGFFAHAGFCLEHASCPPGA----GVIAPGTPSQNTQCQ 151
            T N  CRC+  FF ++  C EH  C P      G+I   T + NT+C+
Sbjct: 121 RTQNTKCRCKPNFFCNSTVC-EH--CDPCTKCEHGIIKECTLTSNTKCK 166


>gi|4507587 tumor necrosis factor receptor superfamily, member 7
           precursor [Homo sapiens]
          Length = 260

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 47/173 (27%), Positives = 64/173 (36%), Gaps = 43/173 (24%)

Query: 12  LCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQRPC-RRDSPTTC 70
           LC++  L  L   PA +   E   + W       +L C  C PGTF+ + C +      C
Sbjct: 9   LCVLGTLVGLSATPAPKSCPER--HYWAQG----KLCCQMCEPGTFLVKDCDQHRKAAQC 62

Query: 71  GPC------PPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAG 124
            PC       P H+T+   + E CR+CN          R C  T N  C CR G+     
Sbjct: 63  DPCIPGVSFSPDHHTR--PHCESCRHCN-----SGLLVRNCTITANAECACRNGWQCRDK 115

Query: 125 FCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTAL 177
            C                     T+C P P  + +A   SS+   PH   T L
Sbjct: 116 EC---------------------TECDPLPNPSLTA--RSSQALSPHPQPTHL 145


>gi|21361086 tumor necrosis factor receptor superfamily, member 10a
           [Homo sapiens]
          Length = 468

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 38/121 (31%), Positives = 48/121 (39%), Gaps = 16/121 (13%)

Query: 35  TYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPR-HYTQFWNYLERCRYCNV 93
           T  W  +  GE      CPPG+      R + P  C  C     YT   N L  C  C  
Sbjct: 120 TQQWEHSPLGEL-----CPPGSH-----RSEHPGACNRCTEGVGYTNASNNLFACLPCTA 169

Query: 94  LCGEREEEARACHATHNRACRCRTGFFAH---AGFCLE-HASCPPGAGVIAPGTPSQNTQ 149
            C   EEE   C  T N AC+C+ G F +   A  C +    CP G   +   TP  + +
Sbjct: 170 -CKSDEEERSPCTTTRNTACQCKPGTFRNDNSAEMCRKCSRGCPRGMVKVKDCTPWSDIE 228

Query: 150 C 150
           C
Sbjct: 229 C 229


>gi|4507575 tumor necrosis factor receptor 1 precursor [Homo
           sapiens]
          Length = 455

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 41/156 (26%), Positives = 56/156 (35%), Gaps = 13/156 (8%)

Query: 47  LVCAQCPPGTFVQRPCRRDSPTT-CGPCPPRHYTQFWNYLERCRYCNVLCGER-EEEARA 104
           + C +C  GT++   C      T C  C    +T   N+L  C  C+    E  + E  +
Sbjct: 57  ICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISS 116

Query: 105 CHATHNRACRCRTGFFAHAGF-----CLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFS 159
           C    +  C CR   + H        C   + C  G  V       QNT C  C  G F 
Sbjct: 117 CTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCLNGT-VHLSCQEKQNTVC-TCHAGFFL 174

Query: 160 ASSS--SSEQCQPHRNCTALGLAL--NVPGSSSHDT 191
             +   S   C+    CT L L    NV G+    T
Sbjct: 175 RENECVSCSNCKKSLECTKLCLPQIENVKGTEDSGT 210



 Score = 32.3 bits (72), Expect = 0.52
 Identities = 22/87 (25%), Positives = 33/87 (37%), Gaps = 24/87 (27%)

Query: 96  GEREEEARAC------HATHNRAC--RCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQN 147
           G+RE+    C      H  +N  C  +C  G + +         CP          P Q+
Sbjct: 35  GDREKRDSVCPQGKYIHPQNNSICCTKCHKGTYLYN-------DCPG---------PGQD 78

Query: 148 TQCQPCPPGTFSASSSSSEQCQPHRNC 174
           T C+ C  G+F+AS +    C     C
Sbjct: 79  TDCRECESGSFTASENHLRHCLSCSKC 105


>gi|84490388 R-spondin1 [Homo sapiens]
          Length = 263

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 32/124 (25%), Positives = 50/124 (40%), Gaps = 14/124 (11%)

Query: 49  CAQCPPGTFV--QRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACH 106
           C +C P  F+  +R   R        CPP ++      + +C  C +      E   AC 
Sbjct: 53  CLKCSPKLFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKI------EHCEACF 106

Query: 107 ATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTP--SQNTQCQPCPPGTFSASSSS 164
           + HN   +C+ G + H G C  + +CP G+   A GT   S   QC+      +   S  
Sbjct: 107 S-HNFCTKCKEGLYLHKGRC--YPACPEGSSA-ANGTMECSSPAQCEMSEWSPWGPCSKK 162

Query: 165 SEQC 168
            + C
Sbjct: 163 QQLC 166


>gi|11140823 X-linked ectodysplasin receptor [Homo sapiens]
          Length = 297

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 30/111 (27%), Positives = 40/111 (36%), Gaps = 9/111 (8%)

Query: 44  GERLVCAQCPPGTFVQRPCR--RDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEE 101
           G  + C +C PG  + + C         C  CPPR Y   W +  RC+ C         +
Sbjct: 13  GRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGH-HRCQSCITCAVINRVQ 71

Query: 102 ARACHATHNRAC-RCRTGFFAHAGF-CLEHASCPPGAGVIAPGTPSQNTQC 150
              C AT N  C  C   F+       L+   C P        TP+   QC
Sbjct: 72  KVNCTATSNAVCGDCLPRFYRKTRIGGLQDQECIP----CTKQTPTSEVQC 118


>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
          Length = 1044

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 41/136 (30%), Positives = 47/136 (34%), Gaps = 41/136 (30%)

Query: 52  CPPGTF---VQRPCRRDSPTTCGP------CPPRHYTQFWNYLERCRYCNVLCGEREEEA 102
           C PGT     Q PC+     +C P      C P  YT          YC  LC       
Sbjct: 176 CAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPG-YTGV--------YCEELCPP----- 221

Query: 103 RACHATH-NRACRCRTGFFAH--AGFCLEHASCPPG-AGVIAPGTPSQNTQCQPCPPGTF 158
              H  H    C C+ G   H   G C    +CPPG  G +           QPCPPGTF
Sbjct: 222 -GSHGAHCELRCPCQNGGTCHHITGEC----ACPPGWTGAVC---------AQPCPPGTF 267

Query: 159 SASSSSSEQCQPHRNC 174
             + S    C     C
Sbjct: 268 GQNCSQDCPCHHGGQC 283



 Score = 29.3 bits (64), Expect = 4.4
 Identities = 35/135 (25%), Positives = 45/135 (33%), Gaps = 32/135 (23%)

Query: 49  CAQ-CPPGTFVQ---RPCRRDSPTTC----GPCPPRHYTQFWNYLERCRYCNVLCGEREE 100
           C+Q CPPG +       C   +  +C    G C   H T  W  L    +C   C     
Sbjct: 693 CSQACPPGFWGPACFHACSCHNGASCSAEDGAC---HCTPGWTGL----FCTQRC----- 740

Query: 101 EARACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQC-QPCPPGTFS 159
            A        R C+C+ G           ASC   +G     T      C Q C PGTF 
Sbjct: 741 PAAFFGKDCGRVCQCQNG-----------ASCDHISGKCTCRTGFTGQHCEQRCAPGTFG 789

Query: 160 ASSSSSEQCQPHRNC 174
                  +C  +  C
Sbjct: 790 YGCQQLCECMNNSTC 804



 Score = 28.1 bits (61), Expect = 9.9
 Identities = 36/154 (23%), Positives = 48/154 (31%), Gaps = 35/154 (22%)

Query: 54  PGTFVQRPCRRDSPTTCGP------CPPRHYTQFWNYLERCRY------CNVLCGEREEE 101
           PG  +  PC  D+  +C P      C P       N  E C        C + C    + 
Sbjct: 356 PGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCN--ESCPVGYYGDGCQLPC--TCQN 411

Query: 102 ARACHATHNRACRCRTGFFAH-------AGF----------CLEHASCPPGAGVIAPGTP 144
              CH+     C C  GF          AG           C    +C P  G       
Sbjct: 412 GADCHSITG-GCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEG 470

Query: 145 SQNTQCQ-PCPPGTFSASSSSSEQCQPHRNCTAL 177
            Q   C  PCP GT+  + + S  C     C+ +
Sbjct: 471 WQGLDCTLPCPSGTWGLNCNESCTCANGAACSPI 504


>gi|134244285 Notch homolog 3 [Homo sapiens]
          Length = 2321

 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 55/186 (29%), Positives = 66/186 (35%), Gaps = 43/186 (23%)

Query: 15  VLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQ---------CPPGTFVQRPCRRD 65
           V ALP LL + A  G A  P         G R  C Q         CPPG   +R C+ +
Sbjct: 24  VRALPLLLLL-AGPGAAAPPCLDGSPCANGGR--CTQLPSREAACLCPPGWVGER-CQLE 79

Query: 66  SPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGF----FA 121
            P   GPC  R   Q           +V+ G           T   +CRC  GF     +
Sbjct: 80  DPCHSGPCAGRGVCQ----------SSVVAG-----------TARFSCRCPRGFRGPDCS 118

Query: 122 HAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSS-EQCQPHRNCTALGLA 180
               CL   S P   G      P     C  CPPG    S  S  ++C+    C   G  
Sbjct: 119 LPDPCL---SSPCAHGARCSVGPDGRFLCS-CPPGYQGRSCRSDVDECRVGEPCRHGGTC 174

Query: 181 LNVPGS 186
           LN PGS
Sbjct: 175 LNTPGS 180



 Score = 35.4 bits (80), Expect = 0.062
 Identities = 63/208 (30%), Positives = 78/208 (37%), Gaps = 49/208 (23%)

Query: 46   RLVCAQCPPGTF-VQRPCRRDSPTTCGPCPPRHYTQFWNYLERC-------------RYC 91
            R +C+ CPPGT  V      D    CGP PP        +   C              Y 
Sbjct: 1143 RYLCS-CPPGTLGVLCEINEDD---CGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYT 1198

Query: 92   NVLCGEREEEAR--ACHATHNRACRCRTGFFAHAGF-CLEHA--SCPPGAGVIAP--GTP 144
             + C     E R  ACHA H R C    G     GF CL HA  S P    V++P    P
Sbjct: 1199 GLRCEADINECRSGACHAAHTRDCLQDPG----GGFRCLCHAGFSGPRCQTVLSPCESQP 1254

Query: 145  SQN-TQCQPCP-PG---TFSASSSS---SEQCQ-PHRNCTALGLALNVP-GSSSHDTLCT 194
             Q+  QC+P P PG   TF+   +      +C+   R+C  L   + VP   +     C 
Sbjct: 1255 CQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCA 1314

Query: 195  --------SCTGFPLSTRVPGAEECERA 214
                    SC  FP S   PGA     A
Sbjct: 1315 CPPGLSGPSCRSFPGSP--PGASNASCA 1340



 Score = 31.6 bits (70), Expect = 0.89
 Identities = 49/190 (25%), Positives = 64/190 (33%), Gaps = 28/190 (14%)

Query: 46  RLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLE--RCR----YCNVLCGERE 99
           R +C+ CPPG +  R CR D        P RH     N     RC+    Y   LC    
Sbjct: 141 RFLCS-CPPG-YQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPA 198

Query: 100 EEARACHATHNRACRCRTGFFAHAGFCL---EHASCP------PG-----AGVIAPGTPS 145
                    +   CR ++G   +   CL   E  +C       PG      G    G  +
Sbjct: 199 VPCAPSPCRNGGTCR-QSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNT 257

Query: 146 QNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRV 205
            N QC P   G F        Q QP+  C   G   N  G  S    C    G+   +  
Sbjct: 258 YNCQCPPEWTGQFCTEDVDECQLQPNA-CHNGGTCFNTLGGHS----CVCVNGWTGESCS 312

Query: 206 PGAEECERAV 215
              ++C  AV
Sbjct: 313 QNIDDCATAV 322


>gi|239757286 PREDICTED: similar to Fc fragment of IgG binding protein
            [Homo sapiens]
          Length = 1472

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 37/119 (31%), Positives = 46/119 (38%), Gaps = 22/119 (18%)

Query: 73   CPPRHYTQFWNYLERCRY-CNVLCGEREEEARACHATHNRACRCRTGFFAHAGFCLEHAS 131
            CPP       ++ E C Y C + CG+       C +  +  C C  GF      CL  AS
Sbjct: 1197 CPPH------SHYEACSYGCPLSCGDLPVPG-GCGSECHEGCVCDEGFALSGESCLPLAS 1249

Query: 132  C---------PPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLAL 181
            C         PPG     PG P  ++ C     G  S  SSS   C PH  C   G +L
Sbjct: 1250 CGCVHQGTYHPPGQ-TFYPG-PGCDSLCHCQEGGLVSCESSS---CGPHEACQPSGGSL 1303


>gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo
            sapiens]
          Length = 3003

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 37/119 (31%), Positives = 46/119 (38%), Gaps = 22/119 (18%)

Query: 73   CPPRHYTQFWNYLERCRY-CNVLCGEREEEARACHATHNRACRCRTGFFAHAGFCLEHAS 131
            CPP       ++ E C Y C + CG+       C +  +  C C  GF      CL  AS
Sbjct: 1136 CPPH------SHYEACSYGCPLSCGDLPVPG-GCGSECHEGCVCDEGFALSGESCLPLAS 1188

Query: 132  C---------PPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLAL 181
            C         PPG     PG P  ++ C     G  S  SSS   C PH  C   G +L
Sbjct: 1189 CGCVHQGTYHPPGQ-TFYPG-PGCDSLCHCQEGGLVSCESSS---CGPHEACQPSGGSL 1242



 Score = 32.7 bits (73), Expect = 0.40
 Identities = 21/84 (25%), Positives = 30/84 (35%), Gaps = 8/84 (9%)

Query: 126  CLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPG 185
            C E  SC   +G+          Q   CPPG      + +  C   R    L +  N+  
Sbjct: 2794 CSERCSCSSSSGLTC--------QAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTT 2845

Query: 186  SSSHDTLCTSCTGFPLSTRVPGAE 209
                    TS   + LS+R PG +
Sbjct: 2846 FDGARGATTSPGVYELSSRCPGLQ 2869



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 24/100 (24%), Positives = 32/100 (32%), Gaps = 16/100 (16%)

Query: 105  CHATHNRACRCRTGFFAHAGFCLEHASCP--------PGAGVIAPGTPSQNTQCQPCPPG 156
            C +     C C  GF      C+    C         P   V  PG P    +C+  P G
Sbjct: 2365 CESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG-PECERRCECGPGG 2423

Query: 157  TFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSC 196
              +    ++  C PH  C      L     + H T C  C
Sbjct: 2424 HVTCQEGAA--CGPHEEC-----RLEDGVQACHATGCGRC 2456


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.454 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,243,682
Number of Sequences: 37866
Number of extensions: 850286
Number of successful extensions: 3288
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 125
Number of HSP's that attempted gapping in prelim test: 2906
Number of HSP's gapped (non-prelim): 390
length of query: 300
length of database: 18,247,518
effective HSP length: 102
effective length of query: 198
effective length of database: 14,385,186
effective search space: 2848266828
effective search space used: 2848266828
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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