BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4507585 tumor necrosis factor receptor superfamily, member 6b [Homo sapiens] (300 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|14790170 tumor necrosis factor receptor superfamily, member 6... 634 0.0 gi|4507585 tumor necrosis factor receptor superfamily, member 6b... 634 0.0 gi|148743793 osteoprotegerin precursor [Homo sapiens] 172 3e-43 gi|4507577 tumor necrosis factor receptor 2 precursor [Homo sapi... 129 4e-30 gi|7657039 tumor necrosis factor receptor superfamily, member 21... 115 6e-26 gi|4505039 lymphotoxin beta receptor [Homo sapiens] 115 6e-26 gi|23200041 tumor necrosis factor receptor superfamily, member 1... 95 9e-20 gi|4507565 tumor necrosis factor receptor superfamily, member 11... 92 4e-19 gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens] 83 3e-16 gi|4507579 tumor necrosis factor receptor superfamily, member 4 ... 79 4e-15 gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens] 73 3e-13 gi|68348711 tumor necrosis factor receptor superfamily, member 8... 69 5e-12 gi|5730095 tumor necrosis factor receptor superfamily, member 9 ... 64 1e-10 gi|4505393 nerve growth factor receptor precursor [Homo sapiens] 64 2e-10 gi|23238200 RELT tumor necrosis factor receptor precursor [Homo ... 58 1e-08 gi|21361873 RELT tumor necrosis factor receptor precursor [Homo ... 58 1e-08 gi|4759246 tumor necrosis factor receptor superfamily, member 18... 54 2e-07 gi|23238197 tumor necrosis factor receptor superfamily, member 1... 54 2e-07 gi|23510423 tumor necrosis factor receptor superfamily, member 6... 53 4e-07 gi|23510421 tumor necrosis factor receptor superfamily, member 6... 53 4e-07 gi|4507583 tumor necrosis factor receptor superfamily, member 6 ... 53 4e-07 gi|4507587 tumor necrosis factor receptor superfamily, member 7 ... 52 5e-07 gi|21361086 tumor necrosis factor receptor superfamily, member 1... 51 1e-06 gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapi... 44 2e-04 gi|84490388 R-spondin1 [Homo sapiens] 43 3e-04 gi|11140823 X-linked ectodysplasin receptor [Homo sapiens] 43 3e-04 gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 42 5e-04 gi|134244285 Notch homolog 3 [Homo sapiens] 42 9e-04 gi|239757286 PREDICTED: similar to Fc fragment of IgG binding pr... 41 0.001 gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ... 41 0.001 >gi|14790170 tumor necrosis factor receptor superfamily, member 6b [Homo sapiens] Length = 300 Score = 634 bits (1634), Expect = 0.0 Identities = 300/300 (100%), Positives = 300/300 (100%) Query: 1 MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQR 60 MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQR Sbjct: 1 MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQR 60 Query: 61 PCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFF 120 PCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFF Sbjct: 61 PCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFF 120 Query: 121 AHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLA 180 AHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLA Sbjct: 121 AHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLA 180 Query: 181 LNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISIKRLQRLLQALEAPE 240 LNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISIKRLQRLLQALEAPE Sbjct: 181 LNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISIKRLQRLLQALEAPE 240 Query: 241 GWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMPGLERSVRERFLPVH 300 GWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMPGLERSVRERFLPVH Sbjct: 241 GWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMPGLERSVRERFLPVH 300 >gi|4507585 tumor necrosis factor receptor superfamily, member 6b [Homo sapiens] Length = 300 Score = 634 bits (1634), Expect = 0.0 Identities = 300/300 (100%), Positives = 300/300 (100%) Query: 1 MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQR 60 MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQR Sbjct: 1 MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQR 60 Query: 61 PCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFF 120 PCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFF Sbjct: 61 PCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFF 120 Query: 121 AHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLA 180 AHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLA Sbjct: 121 AHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLA 180 Query: 181 LNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISIKRLQRLLQALEAPE 240 LNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISIKRLQRLLQALEAPE Sbjct: 181 LNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISIKRLQRLLQALEAPE 240 Query: 241 GWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMPGLERSVRERFLPVH 300 GWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMPGLERSVRERFLPVH Sbjct: 241 GWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMPGLERSVRERFLPVH 300 >gi|148743793 osteoprotegerin precursor [Homo sapiens] Length = 401 Score = 172 bits (436), Expect = 3e-43 Identities = 77/187 (41%), Positives = 108/187 (57%), Gaps = 5/187 (2%) Query: 34 PTYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNV 93 P Y D ET +L+C +CPPGT++++ C T C PCP +YT W+ + C YC+ Sbjct: 26 PKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDHYYTDSWHTSDECLYCSP 85 Query: 94 LCGEREEEARACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPC 153 +C E + + C+ THNR C C+ G + FCL+H SCPPG GV+ GTP +NT C+ C Sbjct: 86 VCKELQYVKQECNRTHNRVCECKEGRYLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRC 145 Query: 154 PPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEE--C 211 P G FS +SS C+ H NC+ GL L G+++HD + C+G ST+ G + C Sbjct: 146 PDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNATHDNI---CSGNSESTQKCGIDVTLC 202 Query: 212 ERAVIDF 218 E A F Sbjct: 203 EEAFFRF 209 >gi|4507577 tumor necrosis factor receptor 2 precursor [Homo sapiens] Length = 461 Score = 129 bits (323), Expect = 4e-30 Identities = 72/210 (34%), Positives = 102/210 (48%), Gaps = 18/210 (8%) Query: 8 GLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGER---LVCAQCPPGTFVQRPCRR 64 GL L ALPA + A A P R E ++ + C++C PG + C + Sbjct: 13 GLELWAAAHALPAQV---AFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTK 69 Query: 65 DSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAG 124 S T C C YTQ WN++ C C C + E +AC NR C CR G++ Sbjct: 70 TSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALS 129 Query: 125 ------FCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALG 178 C C PG GV PGT + + C+PC PGTFS ++SS++ C+PH+ C + Sbjct: 130 KQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVA 189 Query: 179 LALNVPGSSSHDTLCTSCTGFPLSTRVPGA 208 +PG++S D +CTS + P + PGA Sbjct: 190 ----IPGNASMDAVCTSTS--PTRSMAPGA 213 >gi|7657039 tumor necrosis factor receptor superfamily, member 21 precursor [Homo sapiens] Length = 655 Score = 115 bits (287), Expect = 6e-26 Identities = 58/169 (34%), Positives = 81/169 (47%) Query: 35 TYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVL 94 TY D TG+ L C +CP GT+V C S C CP +T+ N +E+C C+ Sbjct: 53 TYRHVDRATGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQP 112 Query: 95 CGEREEEARACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCP 154 C E C A +R C C G F C H CP G GV GT +++ +C+ C Sbjct: 113 CPWPMIEKLPCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCA 172 Query: 155 PGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLST 203 GTFS SS +C+ + +C + L + PG+ D +C + F ST Sbjct: 173 RGTFSDVPSSVMKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSST 221 >gi|4505039 lymphotoxin beta receptor [Homo sapiens] Length = 435 Score = 115 bits (287), Expect = 6e-26 Identities = 86/276 (31%), Positives = 117/276 (42%), Gaps = 34/276 (12%) Query: 3 ALEGPGLSLLCLVLALPALLPVPAVRGV----AETPTYPWRDAETGE---RLVCAQCPPG 55 A PGL+ LVL L LL + V +E T ++ E E R+ C++CPPG Sbjct: 6 ATSAPGLAWGPLVLGLFGLLAASQPQAVPPYASENQTCRDQEKEYYEPQHRICCSRCPPG 65 Query: 56 TFVQRPCRRDSPTTCGPCPPRHYTQFWNYL---ERCRYCNVLCGEREEEARACHATHNRA 112 T+V C R T C C Y + WNYL + CR C+ + G EE C + Sbjct: 66 TYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMG--LEEIAPCTSKRKTQ 123 Query: 113 CRCRTGFFAHA-----GFCLEHASCPPGA-GVIAPGTPSQNTQCQPCPPGTFSASSSSSE 166 CRC+ G F A C + CPPG + N C PC G F +SS S Sbjct: 124 CRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSSPSA 183 Query: 167 QCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDIS- 225 +CQPH C GL PG++ DT C + PL + G ++ F ++ Sbjct: 184 RCQPHTRCENQGLVEAAPGTAQSDTTCKNPLE-PLPPEMSGTMLMLAVLLPLAFFLLLAT 242 Query: 226 ------------IKRLQRLLQALEAPEGWGPTPRAG 249 ++L LL+ P+G GP P AG Sbjct: 243 VFSCIWKSHPSLCRKLGSLLK--RRPQGEGPNPVAG 276 >gi|23200041 tumor necrosis factor receptor superfamily, member 14 precursor [Homo sapiens] Length = 283 Score = 94.7 bits (234), Expect = 9e-20 Identities = 55/149 (36%), Positives = 68/149 (45%), Gaps = 10/149 (6%) Query: 49 CAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGERE--EEARACH 106 C +C PG V+ C + T C PCPP Y N L +C C +C +R C Sbjct: 54 CPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQ-MCDPAMGLRASRNCS 112 Query: 107 ATHNRACRCRTGFFA------HAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSA 160 T N C C G F H C +A+ PG V GT SQ+T CQ CPPGTFS Sbjct: 113 RTENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFS- 171 Query: 161 SSSSSEQCQPHRNCTALGLALNVPGSSSH 189 + + E+CQ C+ L SSSH Sbjct: 172 PNGTLEECQHQTKCSWLVTKAGAGTSSSH 200 >gi|4507565 tumor necrosis factor receptor superfamily, member 11a precursor [Homo sapiens] Length = 616 Score = 92.4 bits (228), Expect = 4e-19 Identities = 48/150 (32%), Positives = 72/150 (48%), Gaps = 3/150 (2%) Query: 49 CAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVL-CGEREEEARACHA 107 C +C PG ++ C S + C PC P Y WN ++C V G+ A ++ Sbjct: 47 CNKCEPGKYMSSKCTTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNS 106 Query: 108 THNRACRCRTGFF--AHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSS 165 T R C C G+ C + C PG G P +++T C+PC G FS + SS+ Sbjct: 107 TTPRRCACTAGYHWSQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSST 166 Query: 166 EQCQPHRNCTALGLALNVPGSSSHDTLCTS 195 ++C+P NCT LG + G+ D +C+S Sbjct: 167 DKCRPWTNCTFLGKRVEHHGTEKSDAVCSS 196 Score = 40.0 bits (92), Expect = 0.003 Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 9/94 (9%) Query: 120 FAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNC-TALG 178 + H G C C PG + + T + ++ C PC P + S + ++C H+ C T Sbjct: 40 YEHLGRCCN--KCEPGKYMSSKCTTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKA 97 Query: 179 LALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECE 212 L V G+S+ C G+ S ++CE Sbjct: 98 LVAVVAGNSTTPRRCACTAGYHWS------QDCE 125 >gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens] Length = 277 Score = 83.2 bits (204), Expect = 3e-16 Identities = 46/151 (30%), Positives = 67/151 (44%), Gaps = 8/151 (5%) Query: 49 CAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERC---RYCNVLCGEREEEARAC 105 C+ C PG + C + T C PC + WN C +YC+ G R ++ Sbjct: 38 CSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCDPNLGLRVQQKGTS 97 Query: 106 HATHNRACRCRTGFFAHAGFC---LEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASS 162 + C C G+ + C + H SC PG GV T +T C+PCP G FS S Sbjct: 98 ET--DTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVS 155 Query: 163 SSSEQCQPHRNCTALGLALNVPGSSSHDTLC 193 S+ E+C P +C L + G++ D +C Sbjct: 156 SAFEKCHPWTSCETKDLVVQQAGTNKTDVVC 186 Score = 47.8 bits (112), Expect = 1e-05 Identities = 33/127 (25%), Positives = 55/127 (43%), Gaps = 10/127 (7%) Query: 104 ACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSS 163 A H ACR + + ++ C + C PG +++ T T+C PC F + + Sbjct: 17 AVHPEPPTACREKQ-YLINSQCC---SLCQPGQKLVSDCTEFTETECLPCGESEFLDTWN 72 Query: 164 SSEQCQPHRNCTA-LGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQ 222 C H+ C LGL + G+S DT+CT G+ + +E CE V+ Sbjct: 73 RETHCHQHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCT-----SEACESCVLHRSCSP 127 Query: 223 DISIKRL 229 +K++ Sbjct: 128 GFGVKQI 134 >gi|4507579 tumor necrosis factor receptor superfamily, member 4 precursor [Homo sapiens] Length = 277 Score = 79.3 bits (194), Expect = 4e-15 Identities = 59/190 (31%), Positives = 75/190 (39%), Gaps = 36/190 (18%) Query: 6 GPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQRPCRRD 65 GP +LL L L L + + V TYP D C +C PG + C R Sbjct: 11 GPCAALLLLGLGLSTVTGLHCVGD-----TYPSNDR------CCHECRPGNGMVSRCSRS 59 Query: 66 SPTTCGPCPPRHYTQFWNY--LERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHA 123 T C PC P Y + + C +CN+ G E + C AT + CRCR G Sbjct: 60 QNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSG--SERKQLCTATQDTVCRCRAG----- 112 Query: 124 GFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNV 183 S PG C PCPPG F S ++ C+P NCT G Sbjct: 113 --TQPLDSYKPG------------VDCAPCPPGHF--SPGDNQACKPWTNCTLAGKHTLQ 156 Query: 184 PGSSSHDTLC 193 P S+S D +C Sbjct: 157 PASNSSDAIC 166 Score = 43.9 bits (102), Expect = 2e-04 Identities = 28/80 (35%), Positives = 41/80 (51%), Gaps = 3/80 (3%) Query: 132 CPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCT-ALGLALNVPGSSSHD 190 C PG G+++ + SQNT C+PC PG F SS+ C+P C G +++ D Sbjct: 46 CRPGNGMVSRCSRSQNTVCRPCGPG-FYNDVVSSKPCKPCTWCNLRSGSERKQLCTATQD 104 Query: 191 TLCTSCTGF-PLSTRVPGAE 209 T+C G PL + PG + Sbjct: 105 TVCRCRAGTQPLDSYKPGVD 124 >gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens] Length = 203 Score = 72.8 bits (177), Expect = 3e-13 Identities = 41/128 (32%), Positives = 57/128 (44%), Gaps = 8/128 (6%) Query: 49 CAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERC---RYCNVLCGEREEEARAC 105 C+ C PG + C + T C PC + WN C +YC+ G R ++ Sbjct: 38 CSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCDPNLGLRVQQKGTS 97 Query: 106 HATHNRACRCRTGFFAHAGFC---LEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASS 162 + C C G+ + C + H SC PG GV T +T C+PCP G FS S Sbjct: 98 ET--DTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVS 155 Query: 163 SSSEQCQP 170 S+ E+C P Sbjct: 156 SAFEKCHP 163 Score = 47.8 bits (112), Expect = 1e-05 Identities = 33/127 (25%), Positives = 55/127 (43%), Gaps = 10/127 (7%) Query: 104 ACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSS 163 A H ACR + + ++ C + C PG +++ T T+C PC F + + Sbjct: 17 AVHPEPPTACREKQ-YLINSQCC---SLCQPGQKLVSDCTEFTETECLPCGESEFLDTWN 72 Query: 164 SSEQCQPHRNCTA-LGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQ 222 C H+ C LGL + G+S DT+CT G+ + +E CE V+ Sbjct: 73 RETHCHQHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCT-----SEACESCVLHRSCSP 127 Query: 223 DISIKRL 229 +K++ Sbjct: 128 GFGVKQI 134 Score = 28.5 bits (62), Expect = 7.6 Identities = 16/62 (25%), Positives = 23/62 (37%) Query: 52 CPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNR 111 C PG V++ S T C PCP ++ + E+C G E H + Sbjct: 125 CSPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHPWTRSPGSAESPGGDPHHLRDP 184 Query: 112 AC 113 C Sbjct: 185 VC 186 >gi|68348711 tumor necrosis factor receptor superfamily, member 8 isoform 1 precursor [Homo sapiens] Length = 595 Score = 68.9 bits (167), Expect = 5e-12 Identities = 43/131 (32%), Positives = 57/131 (43%), Gaps = 12/131 (9%) Query: 46 RLVCAQCPPGTFVQRPCRRDSPTTCGP-CPPRHYTQFWNYLERCRYCNVLCGEREEEARA 104 R C +CP G F + C + PT C C P +Y + +RC C + E Sbjct: 42 RRCCYRCPMGLFPTQQCPQ-RPTDCRKQCEPDYYL---DEADRCTACVTCSRDDLVEKTP 97 Query: 105 CHATHNRACRCRTGFFAHAGF------CLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTF 158 C +R C CR G F C H+ CP G V PGT +NT C+P PG Sbjct: 98 CAWNSSRVCECRPGMFCSTSAVNSCARCFFHSVCPAGMIVKFPGTAQKNTVCEPASPGV- 156 Query: 159 SASSSSSEQCQ 169 S + +S E C+ Sbjct: 157 SPACASPENCK 167 Score = 32.3 bits (72), Expect = 0.52 Identities = 21/81 (25%), Positives = 26/81 (32%), Gaps = 3/81 (3%) Query: 54 PGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRAC 113 PG +PC S C P +Y + RC C + E C +R C Sbjct: 225 PGLSPTQPCPEGSGDCRKQCEPDYYL---DEAGRCTACVSCSRDDLVEKTPCAWNSSRTC 281 Query: 114 RCRTGFFAHAGFCLEHASCPP 134 CR G A C P Sbjct: 282 ECRPGMICATSATNSRARCVP 302 >gi|5730095 tumor necrosis factor receptor superfamily, member 9 precursor [Homo sapiens] Length = 255 Score = 64.3 bits (155), Expect = 1e-10 Identities = 43/148 (29%), Positives = 61/148 (41%), Gaps = 20/148 (13%) Query: 49 CAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNY--LERCRYCNVLCGEREEEARACH 106 C+ CP GTF C + C PCPP ++ + CR C + R+E C Sbjct: 28 CSNCPAGTF----CDNNRNQICSPCPPNSFSSAGGQRTCDICRQCKGVFRTRKE----CS 79 Query: 107 ATHNRACRCRTGFFA-HAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSS 165 +T N C C GF AG + C G + G C+ C GTF+ Sbjct: 80 STSNAECDCTPGFHCLGAGCSMCEQDCKQGQELTKKG-------CKDCCFGTFNDQKRGI 132 Query: 166 EQCQPHRNCTALGLALNVPGSSSHDTLC 193 C+P NC+ G ++ V G+ D +C Sbjct: 133 --CRPWTNCSLDGKSVLVNGTKERDVVC 158 Score = 30.4 bits (67), Expect = 2.0 Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 6/70 (8%) Query: 130 ASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSH 189 ++CP G ++N C PCPP +FS S+ C R C + SS+ Sbjct: 29 SNCPAGTFC----DNNRNQICSPCPPNSFS-SAGGQRTCDICRQCKGV-FRTRKECSSTS 82 Query: 190 DTLCTSCTGF 199 + C GF Sbjct: 83 NAECDCTPGF 92 >gi|4505393 nerve growth factor receptor precursor [Homo sapiens] Length = 427 Score = 63.5 bits (153), Expect = 2e-10 Identities = 49/176 (27%), Positives = 74/176 (42%), Gaps = 16/176 (9%) Query: 2 RALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQRP 61 RA++GP L LL L+ + + + T Y +GE C C G V +P Sbjct: 8 RAMDGPRLLLLLLLG-----VSLGGAKEACPTGLY----THSGE--CCKACNLGEGVAQP 56 Query: 62 CRRDSPTTCGPCPPR-HYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFF 120 C + T C PC ++ + E C+ C G + A C + CRC G++ Sbjct: 57 CGANQ-TVCEPCLDSVTFSDVVSATEPCKPCTECVGLQSMSA-PCVEADDAVCRCAYGYY 114 Query: 121 AH--AGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNC 174 G C C G+G++ QNT C+ CP GT+S ++ + C P C Sbjct: 115 QDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVC 170 Score = 49.3 bits (116), Expect = 4e-06 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 5/98 (5%) Query: 115 CRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPG-TFSASSSSSEQCQPHRN 173 C TG + H+G C + +C G GV P +Q T C+PC TFS S++E C+P Sbjct: 32 CPTGLYTHSGECCK--ACNLGEGVAQPCGANQ-TVCEPCLDSVTFSDVVSATEPCKPCTE 88 Query: 174 CTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEEC 211 C L +++ P + D +C G+ E C Sbjct: 89 CVGL-QSMSAPCVEADDAVCRCAYGYYQDETTGRCEAC 125 >gi|23238200 RELT tumor necrosis factor receptor precursor [Homo sapiens] Length = 430 Score = 57.8 bits (138), Expect = 1e-08 Identities = 30/65 (46%), Positives = 35/65 (53%), Gaps = 3/65 (4%) Query: 132 CPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDT 191 CPPG P Q T C+PCPPGTFSA+ SS CQPH C+ G ++ DT Sbjct: 32 CPPGEEPDLD--PGQGTLCRPCPPGTFSAAWGSS-PCQPHARCSLWRRLEAQVGMATRDT 88 Query: 192 LCTSC 196 LC C Sbjct: 89 LCGDC 93 Score = 35.4 bits (80), Expect = 0.062 Identities = 21/76 (27%), Positives = 29/76 (38%), Gaps = 7/76 (9%) Query: 11 LLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTC 70 L C ++ LP L + + P D + G+ +C CPPGTF + Sbjct: 10 LSCFLMLLPWPLATLTSTTLWQCPPGEEPDLDPGQGTLCRPCPPGTF-------SAAWGS 62 Query: 71 GPCPPRHYTQFWNYLE 86 PC P W LE Sbjct: 63 SPCQPHARCSLWRRLE 78 >gi|21361873 RELT tumor necrosis factor receptor precursor [Homo sapiens] Length = 430 Score = 57.8 bits (138), Expect = 1e-08 Identities = 30/65 (46%), Positives = 35/65 (53%), Gaps = 3/65 (4%) Query: 132 CPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDT 191 CPPG P Q T C+PCPPGTFSA+ SS CQPH C+ G ++ DT Sbjct: 32 CPPGEEPDLD--PGQGTLCRPCPPGTFSAAWGSS-PCQPHARCSLWRRLEAQVGMATRDT 88 Query: 192 LCTSC 196 LC C Sbjct: 89 LCGDC 93 Score = 35.4 bits (80), Expect = 0.062 Identities = 21/76 (27%), Positives = 29/76 (38%), Gaps = 7/76 (9%) Query: 11 LLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTC 70 L C ++ LP L + + P D + G+ +C CPPGTF + Sbjct: 10 LSCFLMLLPWPLATLTSTTLWQCPPGEEPDLDPGQGTLCRPCPPGTF-------SAAWGS 62 Query: 71 GPCPPRHYTQFWNYLE 86 PC P W LE Sbjct: 63 SPCQPHARCSLWRRLE 78 >gi|4759246 tumor necrosis factor receptor superfamily, member 18 isoform 1 precursor [Homo sapiens] Length = 241 Score = 53.5 bits (127), Expect = 2e-07 Identities = 34/110 (30%), Positives = 42/110 (38%), Gaps = 19/110 (17%) Query: 101 EARACHATHNRACRCRTG---------------FFAHAGFCL--EHASCPPGAGVIAPGT 143 +AR C R CR G F C H CPPG GV + G Sbjct: 46 DARCCRVHTTRCCRDYPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGK 105 Query: 144 PSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLC 193 S QC C GTFS C+P +CT G PG+ +H+ +C Sbjct: 106 FSFGFQCIDCASGTFSGGHEG--HCKPWTDCTQFGFLTVFPGNKTHNAVC 153 >gi|23238197 tumor necrosis factor receptor superfamily, member 18 isoform 3 precursor [Homo sapiens] Length = 234 Score = 53.5 bits (127), Expect = 2e-07 Identities = 34/110 (30%), Positives = 42/110 (38%), Gaps = 19/110 (17%) Query: 101 EARACHATHNRACRCRTG---------------FFAHAGFCL--EHASCPPGAGVIAPGT 143 +AR C R CR G F C H CPPG GV + G Sbjct: 46 DARCCRVHTTRCCRDYPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGK 105 Query: 144 PSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLC 193 S QC C GTFS C+P +CT G PG+ +H+ +C Sbjct: 106 FSFGFQCIDCASGTFSGGHEG--HCKPWTDCTQFGFLTVFPGNKTHNAVC 153 >gi|23510423 tumor necrosis factor receptor superfamily, member 6 isoform 3 precursor [Homo sapiens] Length = 220 Score = 52.8 bits (125), Expect = 4e-07 Identities = 39/109 (35%), Positives = 50/109 (45%), Gaps = 14/109 (12%) Query: 52 CPPGTFVQRPC--RRDSPTTCGPCPP-RHYTQFWNYLERCRYCNVLCGERE--EEARACH 106 CPPG R C D P C PC + YT ++ +CR C LC E E C Sbjct: 63 CPPGERKARDCTVNGDEPD-CVPCQEGKEYTDKAHFSSKCRRCR-LCDEGHGLEVEINCT 120 Query: 107 ATHNRACRCRTGFFAHAGFCLEHASCPPGA----GVIAPGTPSQNTQCQ 151 T N CRC+ FF ++ C EH C P G+I T + NT+C+ Sbjct: 121 RTQNTKCRCKPNFFCNSTVC-EH--CDPCTKCEHGIIKECTLTSNTKCK 166 >gi|23510421 tumor necrosis factor receptor superfamily, member 6 isoform 2 precursor [Homo sapiens] Length = 314 Score = 52.8 bits (125), Expect = 4e-07 Identities = 39/109 (35%), Positives = 50/109 (45%), Gaps = 14/109 (12%) Query: 52 CPPGTFVQRPC--RRDSPTTCGPCPP-RHYTQFWNYLERCRYCNVLCGERE--EEARACH 106 CPPG R C D P C PC + YT ++ +CR C LC E E C Sbjct: 63 CPPGERKARDCTVNGDEPD-CVPCQEGKEYTDKAHFSSKCRRCR-LCDEGHGLEVEINCT 120 Query: 107 ATHNRACRCRTGFFAHAGFCLEHASCPPGA----GVIAPGTPSQNTQCQ 151 T N CRC+ FF ++ C EH C P G+I T + NT+C+ Sbjct: 121 RTQNTKCRCKPNFFCNSTVC-EH--CDPCTKCEHGIIKECTLTSNTKCK 166 >gi|4507583 tumor necrosis factor receptor superfamily, member 6 isoform 1 precursor [Homo sapiens] Length = 335 Score = 52.8 bits (125), Expect = 4e-07 Identities = 39/109 (35%), Positives = 50/109 (45%), Gaps = 14/109 (12%) Query: 52 CPPGTFVQRPC--RRDSPTTCGPCPP-RHYTQFWNYLERCRYCNVLCGERE--EEARACH 106 CPPG R C D P C PC + YT ++ +CR C LC E E C Sbjct: 63 CPPGERKARDCTVNGDEPD-CVPCQEGKEYTDKAHFSSKCRRCR-LCDEGHGLEVEINCT 120 Query: 107 ATHNRACRCRTGFFAHAGFCLEHASCPPGA----GVIAPGTPSQNTQCQ 151 T N CRC+ FF ++ C EH C P G+I T + NT+C+ Sbjct: 121 RTQNTKCRCKPNFFCNSTVC-EH--CDPCTKCEHGIIKECTLTSNTKCK 166 >gi|4507587 tumor necrosis factor receptor superfamily, member 7 precursor [Homo sapiens] Length = 260 Score = 52.4 bits (124), Expect = 5e-07 Identities = 47/173 (27%), Positives = 64/173 (36%), Gaps = 43/173 (24%) Query: 12 LCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQRPC-RRDSPTTC 70 LC++ L L PA + E + W +L C C PGTF+ + C + C Sbjct: 9 LCVLGTLVGLSATPAPKSCPER--HYWAQG----KLCCQMCEPGTFLVKDCDQHRKAAQC 62 Query: 71 GPC------PPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAG 124 PC P H+T+ + E CR+CN R C T N C CR G+ Sbjct: 63 DPCIPGVSFSPDHHTR--PHCESCRHCN-----SGLLVRNCTITANAECACRNGWQCRDK 115 Query: 125 FCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTAL 177 C T+C P P + +A SS+ PH T L Sbjct: 116 EC---------------------TECDPLPNPSLTA--RSSQALSPHPQPTHL 145 >gi|21361086 tumor necrosis factor receptor superfamily, member 10a [Homo sapiens] Length = 468 Score = 50.8 bits (120), Expect = 1e-06 Identities = 38/121 (31%), Positives = 48/121 (39%), Gaps = 16/121 (13%) Query: 35 TYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPR-HYTQFWNYLERCRYCNV 93 T W + GE CPPG+ R + P C C YT N L C C Sbjct: 120 TQQWEHSPLGEL-----CPPGSH-----RSEHPGACNRCTEGVGYTNASNNLFACLPCTA 169 Query: 94 LCGEREEEARACHATHNRACRCRTGFFAH---AGFCLE-HASCPPGAGVIAPGTPSQNTQ 149 C EEE C T N AC+C+ G F + A C + CP G + TP + + Sbjct: 170 -CKSDEEERSPCTTTRNTACQCKPGTFRNDNSAEMCRKCSRGCPRGMVKVKDCTPWSDIE 228 Query: 150 C 150 C Sbjct: 229 C 229 >gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapiens] Length = 455 Score = 43.5 bits (101), Expect = 2e-04 Identities = 41/156 (26%), Positives = 56/156 (35%), Gaps = 13/156 (8%) Query: 47 LVCAQCPPGTFVQRPCRRDSPTT-CGPCPPRHYTQFWNYLERCRYCNVLCGER-EEEARA 104 + C +C GT++ C T C C +T N+L C C+ E + E + Sbjct: 57 ICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISS 116 Query: 105 CHATHNRACRCRTGFFAHAGF-----CLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFS 159 C + C CR + H C + C G V QNT C C G F Sbjct: 117 CTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCLNGT-VHLSCQEKQNTVC-TCHAGFFL 174 Query: 160 ASSS--SSEQCQPHRNCTALGLAL--NVPGSSSHDT 191 + S C+ CT L L NV G+ T Sbjct: 175 RENECVSCSNCKKSLECTKLCLPQIENVKGTEDSGT 210 Score = 32.3 bits (72), Expect = 0.52 Identities = 22/87 (25%), Positives = 33/87 (37%), Gaps = 24/87 (27%) Query: 96 GEREEEARAC------HATHNRAC--RCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQN 147 G+RE+ C H +N C +C G + + CP P Q+ Sbjct: 35 GDREKRDSVCPQGKYIHPQNNSICCTKCHKGTYLYN-------DCPG---------PGQD 78 Query: 148 TQCQPCPPGTFSASSSSSEQCQPHRNC 174 T C+ C G+F+AS + C C Sbjct: 79 TDCRECESGSFTASENHLRHCLSCSKC 105 >gi|84490388 R-spondin1 [Homo sapiens] Length = 263 Score = 43.1 bits (100), Expect = 3e-04 Identities = 32/124 (25%), Positives = 50/124 (40%), Gaps = 14/124 (11%) Query: 49 CAQCPPGTFV--QRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACH 106 C +C P F+ +R R CPP ++ + +C C + E AC Sbjct: 53 CLKCSPKLFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKI------EHCEACF 106 Query: 107 ATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTP--SQNTQCQPCPPGTFSASSSS 164 + HN +C+ G + H G C + +CP G+ A GT S QC+ + S Sbjct: 107 S-HNFCTKCKEGLYLHKGRC--YPACPEGSSA-ANGTMECSSPAQCEMSEWSPWGPCSKK 162 Query: 165 SEQC 168 + C Sbjct: 163 QQLC 166 >gi|11140823 X-linked ectodysplasin receptor [Homo sapiens] Length = 297 Score = 43.1 bits (100), Expect = 3e-04 Identities = 30/111 (27%), Positives = 40/111 (36%), Gaps = 9/111 (8%) Query: 44 GERLVCAQCPPGTFVQRPCR--RDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEE 101 G + C +C PG + + C C CPPR Y W + RC+ C + Sbjct: 13 GRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGH-HRCQSCITCAVINRVQ 71 Query: 102 ARACHATHNRAC-RCRTGFFAHAGF-CLEHASCPPGAGVIAPGTPSQNTQC 150 C AT N C C F+ L+ C P TP+ QC Sbjct: 72 KVNCTATSNAVCGDCLPRFYRKTRIGGLQDQECIP----CTKQTPTSEVQC 118 >gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] Length = 1044 Score = 42.4 bits (98), Expect = 5e-04 Identities = 41/136 (30%), Positives = 47/136 (34%), Gaps = 41/136 (30%) Query: 52 CPPGTF---VQRPCRRDSPTTCGP------CPPRHYTQFWNYLERCRYCNVLCGEREEEA 102 C PGT Q PC+ +C P C P YT YC LC Sbjct: 176 CAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPG-YTGV--------YCEELCPP----- 221 Query: 103 RACHATH-NRACRCRTGFFAH--AGFCLEHASCPPG-AGVIAPGTPSQNTQCQPCPPGTF 158 H H C C+ G H G C +CPPG G + QPCPPGTF Sbjct: 222 -GSHGAHCELRCPCQNGGTCHHITGEC----ACPPGWTGAVC---------AQPCPPGTF 267 Query: 159 SASSSSSEQCQPHRNC 174 + S C C Sbjct: 268 GQNCSQDCPCHHGGQC 283 Score = 29.3 bits (64), Expect = 4.4 Identities = 35/135 (25%), Positives = 45/135 (33%), Gaps = 32/135 (23%) Query: 49 CAQ-CPPGTFVQ---RPCRRDSPTTC----GPCPPRHYTQFWNYLERCRYCNVLCGEREE 100 C+Q CPPG + C + +C G C H T W L +C C Sbjct: 693 CSQACPPGFWGPACFHACSCHNGASCSAEDGAC---HCTPGWTGL----FCTQRC----- 740 Query: 101 EARACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQC-QPCPPGTFS 159 A R C+C+ G ASC +G T C Q C PGTF Sbjct: 741 PAAFFGKDCGRVCQCQNG-----------ASCDHISGKCTCRTGFTGQHCEQRCAPGTFG 789 Query: 160 ASSSSSEQCQPHRNC 174 +C + C Sbjct: 790 YGCQQLCECMNNSTC 804 Score = 28.1 bits (61), Expect = 9.9 Identities = 36/154 (23%), Positives = 48/154 (31%), Gaps = 35/154 (22%) Query: 54 PGTFVQRPCRRDSPTTCGP------CPPRHYTQFWNYLERCRY------CNVLCGEREEE 101 PG + PC D+ +C P C P N E C C + C + Sbjct: 356 PGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCN--ESCPVGYYGDGCQLPC--TCQN 411 Query: 102 ARACHATHNRACRCRTGFFAH-------AGF----------CLEHASCPPGAGVIAPGTP 144 CH+ C C GF AG C +C P G Sbjct: 412 GADCHSITG-GCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEG 470 Query: 145 SQNTQCQ-PCPPGTFSASSSSSEQCQPHRNCTAL 177 Q C PCP GT+ + + S C C+ + Sbjct: 471 WQGLDCTLPCPSGTWGLNCNESCTCANGAACSPI 504 >gi|134244285 Notch homolog 3 [Homo sapiens] Length = 2321 Score = 41.6 bits (96), Expect = 9e-04 Identities = 55/186 (29%), Positives = 66/186 (35%), Gaps = 43/186 (23%) Query: 15 VLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQ---------CPPGTFVQRPCRRD 65 V ALP LL + A G A P G R C Q CPPG +R C+ + Sbjct: 24 VRALPLLLLL-AGPGAAAPPCLDGSPCANGGR--CTQLPSREAACLCPPGWVGER-CQLE 79 Query: 66 SPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGF----FA 121 P GPC R Q +V+ G T +CRC GF + Sbjct: 80 DPCHSGPCAGRGVCQ----------SSVVAG-----------TARFSCRCPRGFRGPDCS 118 Query: 122 HAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSS-EQCQPHRNCTALGLA 180 CL S P G P C CPPG S S ++C+ C G Sbjct: 119 LPDPCL---SSPCAHGARCSVGPDGRFLCS-CPPGYQGRSCRSDVDECRVGEPCRHGGTC 174 Query: 181 LNVPGS 186 LN PGS Sbjct: 175 LNTPGS 180 Score = 35.4 bits (80), Expect = 0.062 Identities = 63/208 (30%), Positives = 78/208 (37%), Gaps = 49/208 (23%) Query: 46 RLVCAQCPPGTF-VQRPCRRDSPTTCGPCPPRHYTQFWNYLERC-------------RYC 91 R +C+ CPPGT V D CGP PP + C Y Sbjct: 1143 RYLCS-CPPGTLGVLCEINEDD---CGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYT 1198 Query: 92 NVLCGEREEEAR--ACHATHNRACRCRTGFFAHAGF-CLEHA--SCPPGAGVIAP--GTP 144 + C E R ACHA H R C G GF CL HA S P V++P P Sbjct: 1199 GLRCEADINECRSGACHAAHTRDCLQDPG----GGFRCLCHAGFSGPRCQTVLSPCESQP 1254 Query: 145 SQN-TQCQPCP-PG---TFSASSSS---SEQCQ-PHRNCTALGLALNVP-GSSSHDTLCT 194 Q+ QC+P P PG TF+ + +C+ R+C L + VP + C Sbjct: 1255 CQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCA 1314 Query: 195 --------SCTGFPLSTRVPGAEECERA 214 SC FP S PGA A Sbjct: 1315 CPPGLSGPSCRSFPGSP--PGASNASCA 1340 Score = 31.6 bits (70), Expect = 0.89 Identities = 49/190 (25%), Positives = 64/190 (33%), Gaps = 28/190 (14%) Query: 46 RLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLE--RCR----YCNVLCGERE 99 R +C+ CPPG + R CR D P RH N RC+ Y LC Sbjct: 141 RFLCS-CPPG-YQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPA 198 Query: 100 EEARACHATHNRACRCRTGFFAHAGFCL---EHASCP------PG-----AGVIAPGTPS 145 + CR ++G + CL E +C PG G G + Sbjct: 199 VPCAPSPCRNGGTCR-QSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNT 257 Query: 146 QNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRV 205 N QC P G F Q QP+ C G N G S C G+ + Sbjct: 258 YNCQCPPEWTGQFCTEDVDECQLQPNA-CHNGGTCFNTLGGHS----CVCVNGWTGESCS 312 Query: 206 PGAEECERAV 215 ++C AV Sbjct: 313 QNIDDCATAV 322 >gi|239757286 PREDICTED: similar to Fc fragment of IgG binding protein [Homo sapiens] Length = 1472 Score = 41.2 bits (95), Expect = 0.001 Identities = 37/119 (31%), Positives = 46/119 (38%), Gaps = 22/119 (18%) Query: 73 CPPRHYTQFWNYLERCRY-CNVLCGEREEEARACHATHNRACRCRTGFFAHAGFCLEHAS 131 CPP ++ E C Y C + CG+ C + + C C GF CL AS Sbjct: 1197 CPPH------SHYEACSYGCPLSCGDLPVPG-GCGSECHEGCVCDEGFALSGESCLPLAS 1249 Query: 132 C---------PPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLAL 181 C PPG PG P ++ C G S SSS C PH C G +L Sbjct: 1250 CGCVHQGTYHPPGQ-TFYPG-PGCDSLCHCQEGGLVSCESSS---CGPHEACQPSGGSL 1303 >gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo sapiens] Length = 3003 Score = 41.2 bits (95), Expect = 0.001 Identities = 37/119 (31%), Positives = 46/119 (38%), Gaps = 22/119 (18%) Query: 73 CPPRHYTQFWNYLERCRY-CNVLCGEREEEARACHATHNRACRCRTGFFAHAGFCLEHAS 131 CPP ++ E C Y C + CG+ C + + C C GF CL AS Sbjct: 1136 CPPH------SHYEACSYGCPLSCGDLPVPG-GCGSECHEGCVCDEGFALSGESCLPLAS 1188 Query: 132 C---------PPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLAL 181 C PPG PG P ++ C G S SSS C PH C G +L Sbjct: 1189 CGCVHQGTYHPPGQ-TFYPG-PGCDSLCHCQEGGLVSCESSS---CGPHEACQPSGGSL 1242 Score = 32.7 bits (73), Expect = 0.40 Identities = 21/84 (25%), Positives = 30/84 (35%), Gaps = 8/84 (9%) Query: 126 CLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPG 185 C E SC +G+ Q CPPG + + C R L + N+ Sbjct: 2794 CSERCSCSSSSGLTC--------QAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTT 2845 Query: 186 SSSHDTLCTSCTGFPLSTRVPGAE 209 TS + LS+R PG + Sbjct: 2846 FDGARGATTSPGVYELSSRCPGLQ 2869 Score = 28.9 bits (63), Expect = 5.8 Identities = 24/100 (24%), Positives = 32/100 (32%), Gaps = 16/100 (16%) Query: 105 CHATHNRACRCRTGFFAHAGFCLEHASCP--------PGAGVIAPGTPSQNTQCQPCPPG 156 C + C C GF C+ C P V PG P +C+ P G Sbjct: 2365 CESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG-PECERRCECGPGG 2423 Query: 157 TFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSC 196 + ++ C PH C L + H T C C Sbjct: 2424 HVTCQEGAA--CGPHEEC-----RLEDGVQACHATGCGRC 2456 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.323 0.137 0.454 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,243,682 Number of Sequences: 37866 Number of extensions: 850286 Number of successful extensions: 3288 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 39 Number of HSP's successfully gapped in prelim test: 125 Number of HSP's that attempted gapping in prelim test: 2906 Number of HSP's gapped (non-prelim): 390 length of query: 300 length of database: 18,247,518 effective HSP length: 102 effective length of query: 198 effective length of database: 14,385,186 effective search space: 2848266828 effective search space used: 2848266828 T: 11 A: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.