Guide to the Human Genome
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Name: NOTCH3 Sequence: fasta or formatted (2321aa) NCBI GI: 134244285
Description:

Notch homolog 3

Referenced in:

Notch Pathway

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.5        198           3
 C cysteine           10.0        231           1
 D aspartate           6.0        140           2
 E glutamate           5.0        115           2
 F phenylalanine       2.5         59           2
 G glycine            11.4        264           3
 H histidine           2.6         61           2
 I isoleucine          1.4         33           2
 K lysine              1.2         28           2
 L leucine             7.9        184           5
 M methionine          1.0         23           1
 N asparagine          2.9         67           2
 P proline            10.6        247           7
 Q glutamine           4.0         94           2
 R arginine            6.3        147           6
 S serine              6.8        158           2
 T threonine           4.4        103           3
 V valine              5.0        115           2
 W tryptophan          0.9         20           1
 Y tyrosine            1.5         34           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   Notch homolog 3 
NOTCH1                0.485   notch1 preproprotein 
NOTCH2                0.481   notch 2 preproprotein 
NOTCH4                0.226   notch4 preproprotein 
EYS                   0.099   eyes shut homolog isoform 1 
JAG1                  0.097   jagged 1 precursor 
JAG2                  0.089   jagged 2 isoform a precursor 
MEGF6                 0.086   EGF-like-domain, multiple 3 
FBN2                  0.086   fibrillin 2 precursor 
JAG2                  0.084   jagged 2 isoform b precursor 
FBN3                  0.083   fibrillin 3 precursor 
FBN1                  0.083   fibrillin 1 precursor 
SNED1                 0.082   6720455I24Rik homolog 
CRB1                  0.064   crumbs homolog 1 precursor 
CRB2                  0.061   crumbs homolog 2 
LTBP4                 0.055   latent transforming growth factor beta binding prot...
LTBP4                 0.055   latent transforming growth factor beta binding prot...
LTBP4                 0.055   latent transforming growth factor beta binding prot...
MEGF10                0.050   multiple EGF-like-domains 10 
MEGF11                0.050   multiple EGF-like-domains 11 
DNER                  0.048   delta-notch-like EGF repeat-containing transmembran...
DLL1                  0.048   delta-like 1 
TNXB                  0.047   tenascin XB isoform 1 precursor 
SVEP1                 0.047   polydom 
LTBP2                 0.045   latent transforming growth factor beta binding protei...
PEAR1                 0.042   platelet endothelial aggregation receptor 1 
DLL4                  0.042   delta-like 4 protein precursor 
LTBP1                 0.040   latent transforming growth factor beta binding prote...
LTBP1                 0.040   latent transforming growth factor beta binding prote...
LTBP3                 0.038   latent transforming growth factor beta binding prot...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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