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Search of human proteins with 4507579
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507579 tumor necrosis factor receptor superfamily, member 4
precursor [Homo sapiens]
(277 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507579 tumor necrosis factor receptor superfamily, member 4 ... 597 e-171
gi|4507565 tumor necrosis factor receptor superfamily, member 11... 89 4e-18
gi|14790170 tumor necrosis factor receptor superfamily, member 6... 79 3e-15
gi|4507585 tumor necrosis factor receptor superfamily, member 6b... 79 3e-15
gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens] 77 2e-14
gi|4505393 nerve growth factor receptor precursor [Homo sapiens] 75 6e-14
gi|4505039 lymphotoxin beta receptor [Homo sapiens] 74 1e-13
gi|4507577 tumor necrosis factor receptor 2 precursor [Homo sapi... 73 2e-13
gi|23200041 tumor necrosis factor receptor superfamily, member 1... 70 2e-12
gi|5730095 tumor necrosis factor receptor superfamily, member 9 ... 65 5e-11
gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens] 64 1e-10
gi|4759246 tumor necrosis factor receptor superfamily, member 18... 63 3e-10
gi|23238197 tumor necrosis factor receptor superfamily, member 1... 63 3e-10
gi|148743793 osteoprotegerin precursor [Homo sapiens] 61 9e-10
gi|23238200 RELT tumor necrosis factor receptor precursor [Homo ... 57 1e-08
gi|21361873 RELT tumor necrosis factor receptor precursor [Homo ... 57 1e-08
gi|143770880 laminin, beta 4 [Homo sapiens] 56 4e-08
gi|22547121 tumor necrosis factor receptor superfamily, member 1... 55 5e-08
gi|4507587 tumor necrosis factor receptor superfamily, member 7 ... 54 1e-07
gi|7657039 tumor necrosis factor receptor superfamily, member 21... 50 2e-06
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 49 5e-06
gi|23238194 tumor necrosis factor receptor superfamily, member 1... 49 5e-06
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 49 6e-06
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 49 6e-06
gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapi... 47 1e-05
gi|68348711 tumor necrosis factor receptor superfamily, member 8... 47 2e-05
gi|23510423 tumor necrosis factor receptor superfamily, member 6... 47 2e-05
gi|23510421 tumor necrosis factor receptor superfamily, member 6... 47 2e-05
gi|4507583 tumor necrosis factor receptor superfamily, member 6 ... 47 2e-05
gi|21361086 tumor necrosis factor receptor superfamily, member 1... 46 4e-05
>gi|4507579 tumor necrosis factor receptor superfamily, member 4
precursor [Homo sapiens]
Length = 277
Score = 597 bits (1538), Expect = e-171
Identities = 277/277 (100%), Positives = 277/277 (100%)
Query: 1 MCVGARRLGRGPCAALLLLGLGLSTVTGLHCVGDTYPSNDRCCHECRPGNGMVSRCSRSQ 60
MCVGARRLGRGPCAALLLLGLGLSTVTGLHCVGDTYPSNDRCCHECRPGNGMVSRCSRSQ
Sbjct: 1 MCVGARRLGRGPCAALLLLGLGLSTVTGLHCVGDTYPSNDRCCHECRPGNGMVSRCSRSQ 60
Query: 61 NTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGSERKQLCTATQDTVCRCRAGTQPLDSYK 120
NTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGSERKQLCTATQDTVCRCRAGTQPLDSYK
Sbjct: 61 NTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGSERKQLCTATQDTVCRCRAGTQPLDSYK 120
Query: 121 PGVDCAPCPPGHFSPGDNQACKPWTNCTLAGKHTLQPASNSSDAICEDRDPPATQPQETQ 180
PGVDCAPCPPGHFSPGDNQACKPWTNCTLAGKHTLQPASNSSDAICEDRDPPATQPQETQ
Sbjct: 121 PGVDCAPCPPGHFSPGDNQACKPWTNCTLAGKHTLQPASNSSDAICEDRDPPATQPQETQ 180
Query: 181 GPPARPITVQPTEAWPRTSQGPSTRPVEVPGGRAVAAILGLGLVLGLLGPLAILLALYLL 240
GPPARPITVQPTEAWPRTSQGPSTRPVEVPGGRAVAAILGLGLVLGLLGPLAILLALYLL
Sbjct: 181 GPPARPITVQPTEAWPRTSQGPSTRPVEVPGGRAVAAILGLGLVLGLLGPLAILLALYLL 240
Query: 241 RRDQRLPPDAHKPPGGGSFRTPIQEEQADAHSTLAKI 277
RRDQRLPPDAHKPPGGGSFRTPIQEEQADAHSTLAKI
Sbjct: 241 RRDQRLPPDAHKPPGGGSFRTPIQEEQADAHSTLAKI 277
>gi|4507565 tumor necrosis factor receptor superfamily, member 11a
precursor [Homo sapiens]
Length = 616
Score = 89.0 bits (219), Expect = 4e-18
Identities = 70/210 (33%), Positives = 91/210 (43%), Gaps = 36/210 (17%)
Query: 1 MCVGARRLGRGPCAALLLL-----GLGLSTVTGLHCVGDT-YPSNDRCCHECRPGNGMVS 54
M ARR R P ALLLL L ++ C + Y RCC++C PG M S
Sbjct: 1 MAPRARR--RRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSS 58
Query: 55 RCSRSQNTVCRPCGPGFYNDVVSSK-PCKPCTWCNL----------RSGSERKQLCTA-- 101
+C+ + ++VC PCGP Y D + + C C+ S + R+ CTA
Sbjct: 59 KCTTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGY 118
Query: 102 --TQDTVCRCRAGTQ---------PLDSYKPGVDCAPCPPGHFSP--GDNQACKPWTNCT 148
+QD C CR T+ PL K V C PC G+FS C+PWTNCT
Sbjct: 119 HWSQDCEC-CRRNTECAPGLGAQHPLQLNKDTV-CKPCLAGYFSDAFSSTDKCRPWTNCT 176
Query: 149 LAGKHTLQPASNSSDAICEDRDPPATQPQE 178
GK + SDA+C P P E
Sbjct: 177 FLGKRVEHHGTEKSDAVCSSSLPARKPPNE 206
>gi|14790170 tumor necrosis factor receptor superfamily, member 6b
[Homo sapiens]
Length = 300
Score = 79.3 bits (194), Expect = 3e-15
Identities = 59/190 (31%), Positives = 75/190 (39%), Gaps = 36/190 (18%)
Query: 11 GPCAALLLLGLGLSTVTGLHCVGD-----TYPSNDR------CCHECRPGNGMVSRCSRS 59
GP +LL L L L + + V TYP D C +C PG + C R
Sbjct: 6 GPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQRPCRRD 65
Query: 60 QNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSG--SERKQLCTATQDTVCRCRAG----- 112
T C PC P Y + + C +CN+ G E + C AT + CRCR G
Sbjct: 66 SPTTCGPCPPRHYTQFWNY--LERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHA 123
Query: 113 --TQPLDSYKPG------------VDCAPCPPGHF--SPGDNQACKPWTNCTLAGKHTLQ 156
S PG C PCPPG F S ++ C+P NCT G
Sbjct: 124 GFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNV 183
Query: 157 PASNSSDAIC 166
P S+S D +C
Sbjct: 184 PGSSSHDTLC 193
Score = 43.9 bits (102), Expect = 2e-04
Identities = 28/80 (35%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 46 CRPGNGMVSRCSRSQNTVCRPCGPG-FYNDVVSSKPCKPCTWCNLRSGSERKQLCTATQD 104
C PG G+++ + SQNT C+PC PG F SS+ C+P C G +++ D
Sbjct: 132 CPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCT-ALGLALNVPGSSSHD 190
Query: 105 TVCRCRAGTQPLDSYKPGVD 124
T+C G PL + PG +
Sbjct: 191 TLCTSCTGF-PLSTRVPGAE 209
>gi|4507585 tumor necrosis factor receptor superfamily, member 6b
[Homo sapiens]
Length = 300
Score = 79.3 bits (194), Expect = 3e-15
Identities = 59/190 (31%), Positives = 75/190 (39%), Gaps = 36/190 (18%)
Query: 11 GPCAALLLLGLGLSTVTGLHCVGD-----TYPSNDR------CCHECRPGNGMVSRCSRS 59
GP +LL L L L + + V TYP D C +C PG + C R
Sbjct: 6 GPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQRPCRRD 65
Query: 60 QNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSG--SERKQLCTATQDTVCRCRAG----- 112
T C PC P Y + + C +CN+ G E + C AT + CRCR G
Sbjct: 66 SPTTCGPCPPRHYTQFWNY--LERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHA 123
Query: 113 --TQPLDSYKPG------------VDCAPCPPGHF--SPGDNQACKPWTNCTLAGKHTLQ 156
S PG C PCPPG F S ++ C+P NCT G
Sbjct: 124 GFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNV 183
Query: 157 PASNSSDAIC 166
P S+S D +C
Sbjct: 184 PGSSSHDTLC 193
Score = 43.9 bits (102), Expect = 2e-04
Identities = 28/80 (35%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 46 CRPGNGMVSRCSRSQNTVCRPCGPG-FYNDVVSSKPCKPCTWCNLRSGSERKQLCTATQD 104
C PG G+++ + SQNT C+PC PG F SS+ C+P C G +++ D
Sbjct: 132 CPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCT-ALGLALNVPGSSSHD 190
Query: 105 TVCRCRAGTQPLDSYKPGVD 124
T+C G PL + PG +
Sbjct: 191 TLCTSCTGF-PLSTRVPGAE 209
>gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]
Length = 277
Score = 76.6 bits (187), Expect = 2e-14
Identities = 47/165 (28%), Positives = 66/165 (40%), Gaps = 25/165 (15%)
Query: 31 CVGDTYPSNDRCCHECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKP-CKPCTWCNL 89
C Y N +CC C+PG +VS C+ T C PCG + D + + C +C+
Sbjct: 26 CREKQYLINSQCCSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCDP 85
Query: 90 RSGSERKQLCTATQDTVCRCRAGTQPLD----------SYKPGVD------------CAP 127
G +Q T+ DT+C C G S PG C P
Sbjct: 86 NLGLRVQQKGTSETDTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQIATGVSDTICEP 145
Query: 128 CPPGHFSPGDN--QACKPWTNCTLAGKHTLQPASNSSDAICEDRD 170
CP G FS + + C PWT+C Q +N +D +C +D
Sbjct: 146 CPVGFFSNVSSAFEKCHPWTSCETKDLVVQQAGTNKTDVVCGPQD 190
>gi|4505393 nerve growth factor receptor precursor [Homo sapiens]
Length = 427
Score = 75.1 bits (183), Expect = 6e-14
Identities = 77/253 (30%), Positives = 102/253 (40%), Gaps = 51/253 (20%)
Query: 3 VGARRLGR---GPCAALLLLGLGLSTVTGLH-CVGDTYPSNDRCCHECRPGNGMVSRCSR 58
+GA GR GP LLLL LG+S C Y + CC C G G+ C
Sbjct: 1 MGAGATGRAMDGPRLLLLLL-LGVSLGGAKEACPTGLYTHSGECCKACNLGEGVAQPCGA 59
Query: 59 SQNTVCRPCGPGF-YNDVVS-SKPCKPCTWC-NLRSGSERKQLCTATQDTVCRCRAGTQP 115
+Q TVC PC ++DVVS ++PCKPCT C L+S S C D VCRC G
Sbjct: 60 NQ-TVCEPCLDSVTFSDVVSATEPCKPCTECVGLQSMSAP---CVEADDAVCRCAYGYYQ 115
Query: 116 LDSY---------------------KPGVDCAPCPPGHFSPGDNQA--CKPWTNCTLAGK 152
++ K C CP G +S N C P T C +
Sbjct: 116 DETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVCE-DTE 174
Query: 153 HTLQPASNSSDAICED--------------RDPPATQPQETQGPPARPITVQPTEAWPRT 198
L+ + +DA CE+ D A QE + PP + + + T A T
Sbjct: 175 RQLRECTRWADAECEEIPGRWITRSTPPEGSDSTAPSTQEPEAPPEQDL-IASTVAGVVT 233
Query: 199 SQGPSTRPVEVPG 211
+ S++PV G
Sbjct: 234 TVMGSSQPVVTRG 246
>gi|4505039 lymphotoxin beta receptor [Homo sapiens]
Length = 435
Score = 74.3 bits (181), Expect = 1e-13
Identities = 49/173 (28%), Positives = 70/173 (40%), Gaps = 30/173 (17%)
Query: 37 PSNDRCCHECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKP-CKPCTWCNLRSGSER 95
P + CC C PG + ++CSR ++TVC C YN+ + C+ C C+ G E
Sbjct: 53 PQHRICCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEE 112
Query: 96 KQLCTATQDTVCRCRAG------------TQPLDSYKPGVD-------------CAPCPP 130
CT+ + T CRC+ G + L PG + C PC
Sbjct: 113 IAPCTSKRKTQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKA 172
Query: 131 GHF--SPGDNQACKPWTNCTLAGKHTLQPASNSSDAICEDRDPPATQPQETQG 181
GHF + + C+P T C G P + SD C ++P P E G
Sbjct: 173 GHFQNTSSPSARCQPHTRCENQGLVEAAPGTAQSDTTC--KNPLEPLPPEMSG 223
>gi|4507577 tumor necrosis factor receptor 2 precursor [Homo
sapiens]
Length = 461
Score = 73.2 bits (178), Expect = 2e-13
Identities = 64/230 (27%), Positives = 86/230 (37%), Gaps = 44/230 (19%)
Query: 42 CCHECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGSER--KQLC 99
CC +C PG C+++ +TVC C Y + + P C C R S++ Q C
Sbjct: 53 CCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVP--ECLSCGSRCSSDQVETQAC 110
Query: 100 TATQDTVCRCRAG-------------TQPLDSYKPG------------VDCAPCPPGHFS 134
T Q+ +C CR G PL +PG V C PC PG FS
Sbjct: 111 TREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFS 170
Query: 135 --PGDNQACKPWTNCTLAGKHTLQPASNSSDAICEDRDPPATQ-PQETQGPPARPITVQP 191
C+P C + P + S DA+C P + P P Q
Sbjct: 171 NTTSSTDICRPHQICNVVA----IPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQH 226
Query: 192 TEAWPRTSQGPSTR------PVEVPGGRAVAAILGLGLVLGL--LGPLAI 233
T+ P S PST P G L +GL++G+ LG L I
Sbjct: 227 TQPTPEPSTAPSTSFLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLII 276
>gi|23200041 tumor necrosis factor receptor superfamily, member 14
precursor [Homo sapiens]
Length = 283
Score = 70.1 bits (170), Expect = 2e-12
Identities = 42/145 (28%), Positives = 56/145 (38%), Gaps = 27/145 (18%)
Query: 31 CVGDTYPSNDRCCHECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSS-KPCKPCTWCNL 89
C D YP CC +C PG + C TVC PC PG Y ++ C C C+
Sbjct: 42 CKEDEYPVGSECCPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDP 101
Query: 90 RSGSERKQLCTATQDTVCRCRAG-------------TQPLDSYKPG------------VD 124
G + C+ T++ VC C G + + PG
Sbjct: 102 AMGLRASRNCSRTENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTL 161
Query: 125 CAPCPPGHFSP-GDNQACKPWTNCT 148
C CPPG FSP G + C+ T C+
Sbjct: 162 CQNCPPGTFSPNGTLEECQHQTKCS 186
Score = 30.8 bits (68), Expect = 1.4
Identities = 16/60 (26%), Positives = 30/60 (50%), Gaps = 9/60 (15%)
Query: 43 CHECR------PGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCK---PCTWCNLRSGS 93
C CR PG + + SQ+T+C+ C PG ++ + + C+ C+W ++G+
Sbjct: 135 CAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFSPNGTLEECQHQTKCSWLVTKAGA 194
>gi|5730095 tumor necrosis factor receptor superfamily, member 9
precursor [Homo sapiens]
Length = 255
Score = 65.5 bits (158), Expect = 5e-11
Identities = 39/155 (25%), Positives = 61/155 (39%), Gaps = 19/155 (12%)
Query: 43 CHECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGSERKQLCTAT 102
C C G + C ++N +C PC P ++ + C C C + ++ C++T
Sbjct: 28 CSNCPAG----TFCDNNRNQICSPCPPNSFSSAGGQRTCDICRQC--KGVFRTRKECSST 81
Query: 103 QDTVCRCRAGTQPLDS--------YKPGVD-----CAPCPPGHFSPGDNQACKPWTNCTL 149
+ C C G L + K G + C C G F+ C+PWTNC+L
Sbjct: 82 SNAECDCTPGFHCLGAGCSMCEQDCKQGQELTKKGCKDCCFGTFNDQKRGICRPWTNCSL 141
Query: 150 AGKHTLQPASNSSDAICEDRDPPATQPQETQGPPA 184
GK L + D +C + + PPA
Sbjct: 142 DGKSVLVNGTKERDVVCGPSPADLSPGASSVTPPA 176
>gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]
Length = 203
Score = 63.9 bits (154), Expect = 1e-10
Identities = 41/140 (29%), Positives = 55/140 (39%), Gaps = 25/140 (17%)
Query: 31 CVGDTYPSNDRCCHECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKP-CKPCTWCNL 89
C Y N +CC C+PG +VS C+ T C PCG + D + + C +C+
Sbjct: 26 CREKQYLINSQCCSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCDP 85
Query: 90 RSGSERKQLCTATQDTVCRCRAGTQPLD----------SYKPGVD------------CAP 127
G +Q T+ DT+C C G S PG C P
Sbjct: 86 NLGLRVQQKGTSETDTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQIATGVSDTICEP 145
Query: 128 CPPGHFSPGDN--QACKPWT 145
CP G FS + + C PWT
Sbjct: 146 CPVGFFSNVSSAFEKCHPWT 165
>gi|4759246 tumor necrosis factor receptor superfamily, member 18
isoform 1 precursor [Homo sapiens]
Length = 241
Score = 62.8 bits (151), Expect = 3e-10
Identities = 40/125 (32%), Positives = 50/125 (40%), Gaps = 6/125 (4%)
Query: 49 GNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGSERKQLCTATQDTVCR 108
G G +RC R T C PG + S C C G CT + C
Sbjct: 42 GTGTDARCCRVHTTRCCRDYPG--EECCSEWDCM-CVQPEFHCGDP---CCTTCRHHPCP 95
Query: 109 CRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKPWTNCTLAGKHTLQPASNSSDAICED 168
G Q + G C C G FS G CKPWT+CT G T+ P + + +A+C
Sbjct: 96 PGQGVQSQGKFSFGFQCIDCASGTFSGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVP 155
Query: 169 RDPPA 173
PPA
Sbjct: 156 GSPPA 160
Score = 32.7 bits (73), Expect = 0.36
Identities = 20/62 (32%), Positives = 25/62 (40%), Gaps = 6/62 (9%)
Query: 31 CVGDTYPSNDRCC-----HECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCT 85
CV + D CC H C PG G+ S+ S C C G ++ CKP T
Sbjct: 74 CVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGH-CKPWT 132
Query: 86 WC 87
C
Sbjct: 133 DC 134
>gi|23238197 tumor necrosis factor receptor superfamily, member 18
isoform 3 precursor [Homo sapiens]
Length = 234
Score = 62.8 bits (151), Expect = 3e-10
Identities = 40/125 (32%), Positives = 50/125 (40%), Gaps = 6/125 (4%)
Query: 49 GNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGSERKQLCTATQDTVCR 108
G G +RC R T C PG + S C C G CT + C
Sbjct: 42 GTGTDARCCRVHTTRCCRDYPG--EECCSEWDCM-CVQPEFHCGDP---CCTTCRHHPCP 95
Query: 109 CRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKPWTNCTLAGKHTLQPASNSSDAICED 168
G Q + G C C G FS G CKPWT+CT G T+ P + + +A+C
Sbjct: 96 PGQGVQSQGKFSFGFQCIDCASGTFSGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVP 155
Query: 169 RDPPA 173
PPA
Sbjct: 156 GSPPA 160
Score = 32.7 bits (73), Expect = 0.36
Identities = 20/62 (32%), Positives = 25/62 (40%), Gaps = 6/62 (9%)
Query: 31 CVGDTYPSNDRCC-----HECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCT 85
CV + D CC H C PG G+ S+ S C C G ++ CKP T
Sbjct: 74 CVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGH-CKPWT 132
Query: 86 WC 87
C
Sbjct: 133 DC 134
>gi|148743793 osteoprotegerin precursor [Homo sapiens]
Length = 401
Score = 61.2 bits (147), Expect = 9e-10
Identities = 50/184 (27%), Positives = 69/184 (37%), Gaps = 34/184 (18%)
Query: 13 CAALLLLGLGLSTVTG-------LHCVGDTYPSNDRCCHECRPGNGMVSRCSRSQNTVCR 65
C AL+ L + + T LH +T S+ C +C PG + C+ TVC
Sbjct: 6 CCALVFLDISIKWTTQETFPPKYLHYDEET--SHQLLCDKCPPGTYLKQHCTAKWKTVCA 63
Query: 66 PCGPGFYNDVVSSKPCKPCTWCN--LRSGSERKQLCTATQDTVCRCRAGTQ-------PL 116
PC +Y D S C +C+ + KQ C T + VC C+ G
Sbjct: 64 PCPDHYYTD--SWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYLEIEFCLKH 121
Query: 117 DSYKPGVD------------CAPCPPGHFS--PGDNQACKPWTNCTLAGKHTLQPASNSS 162
S PG C CP G FS C+ TNC++ G Q + +
Sbjct: 122 RSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNATH 181
Query: 163 DAIC 166
D IC
Sbjct: 182 DNIC 185
Score = 48.1 bits (113), Expect = 8e-06
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 6/89 (6%)
Query: 46 CRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSK-PCKPCTWCNLRSGSERKQLCTATQD 104
C PG G+V + +NTVC+ C GF+++ SSK PC+ T C++ G Q AT D
Sbjct: 124 CPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSV-FGLLLTQKGNATHD 182
Query: 105 TVCRCRAGTQPLDSYKPGVDCAPCPPGHF 133
+C + + + K G+D C F
Sbjct: 183 NICSGNSES----TQKCGIDVTLCEEAFF 207
>gi|23238200 RELT tumor necrosis factor receptor precursor [Homo
sapiens]
Length = 430
Score = 57.4 bits (137), Expect = 1e-08
Identities = 67/228 (29%), Positives = 87/228 (38%), Gaps = 56/228 (24%)
Query: 45 ECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGSERKQLCTATQD 104
+C PG Q T+CRPC PG ++ S PC+P C+L E Q+ AT+D
Sbjct: 31 QCPPGEE--PDLDPGQGTLCRPCPPGTFSAAWGSSPCQPHARCSLWRRLE-AQVGMATRD 87
Query: 105 TVC-RCRAGTQPLDSYKP-GVDCAPCPPGHFSPGDNQACKPWTNCTLAGKHTLQPASNSS 162
T+C C G + P GV PC P ++P C W G AS+
Sbjct: 88 TLCGDCWPGW-----FGPWGVPRVPCQPCSWAPLGTHGCDEWGRRARRGVEVAAGASSGG 142
Query: 163 DAICEDRDPPATQPQETQGPPARPITVQPTEAWPRTSQGPSTR---PVEVPGGRAVAAIL 219
E R P G TR P E AV AI+
Sbjct: 143 ----ETRQP-----------------------------GNGTRAGGPEETAAQYAVIAIV 169
Query: 220 GLGLVLGLLGPLAILLALYLLRRDQRLPPDAHK-----PPGGGSFRTP 262
+ ++GLLG +L LL+R + AHK P GGGS P
Sbjct: 170 PVFCLMGLLG----ILVCNLLKR-KGYHCTAHKEVGPGPGGGGSGINP 212
>gi|21361873 RELT tumor necrosis factor receptor precursor [Homo
sapiens]
Length = 430
Score = 57.4 bits (137), Expect = 1e-08
Identities = 67/228 (29%), Positives = 87/228 (38%), Gaps = 56/228 (24%)
Query: 45 ECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGSERKQLCTATQD 104
+C PG Q T+CRPC PG ++ S PC+P C+L E Q+ AT+D
Sbjct: 31 QCPPGEE--PDLDPGQGTLCRPCPPGTFSAAWGSSPCQPHARCSLWRRLE-AQVGMATRD 87
Query: 105 TVC-RCRAGTQPLDSYKP-GVDCAPCPPGHFSPGDNQACKPWTNCTLAGKHTLQPASNSS 162
T+C C G + P GV PC P ++P C W G AS+
Sbjct: 88 TLCGDCWPGW-----FGPWGVPRVPCQPCSWAPLGTHGCDEWGRRARRGVEVAAGASSGG 142
Query: 163 DAICEDRDPPATQPQETQGPPARPITVQPTEAWPRTSQGPSTR---PVEVPGGRAVAAIL 219
E R P G TR P E AV AI+
Sbjct: 143 ----ETRQP-----------------------------GNGTRAGGPEETAAQYAVIAIV 169
Query: 220 GLGLVLGLLGPLAILLALYLLRRDQRLPPDAHK-----PPGGGSFRTP 262
+ ++GLLG +L LL+R + AHK P GGGS P
Sbjct: 170 PVFCLMGLLG----ILVCNLLKR-KGYHCTAHKEVGPGPGGGGSGINP 212
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 55.8 bits (133), Expect = 4e-08
Identities = 37/139 (26%), Positives = 54/139 (38%), Gaps = 14/139 (10%)
Query: 34 DTYPSNDRCCHECRPG---NGMVSRCSRSQN-TVCRPCGPGFY-NDVVSSKPCKPCTWCN 88
D SN H C + ++ C + T C C GFY N +S PC+PC CN
Sbjct: 915 DDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCA-CN 973
Query: 89 LRSGSERKQLCTATQDTVCRCRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKPWTNCT 148
+ C+ RC TQ G +C C PGH+ NQ C+ +C
Sbjct: 974 NNIDVTDPESCSRVTGECLRCLHNTQ-------GANCQLCKPGHYGSALNQTCRR-CSCH 1025
Query: 149 LAGKHTLQPASNSSDAICE 167
+G ++ +C+
Sbjct: 1026 ASGVSPMECPPGGGACLCD 1044
Score = 35.8 bits (81), Expect = 0.042
Identities = 34/137 (24%), Positives = 51/137 (37%), Gaps = 17/137 (12%)
Query: 40 DRCCHECRPGNGMVSRCSR-SQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGSER-KQ 97
+R C P G C + C C G+Y + S +PC+PC + S ++
Sbjct: 866 NRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAH 925
Query: 98 LCTA---TQDTVCRC---RAGTQPLDSY-----KPGVDCAPCPP----GHFSPGDNQACK 142
C + D +C C GTQ + P + APC P + D ++C
Sbjct: 926 SCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCS 985
Query: 143 PWTNCTLAGKHTLQPAS 159
T L H Q A+
Sbjct: 986 RVTGECLRCLHNTQGAN 1002
Score = 31.2 bits (69), Expect = 1.0
Identities = 26/86 (30%), Positives = 33/86 (38%), Gaps = 8/86 (9%)
Query: 64 CRPCGPGFYNDVVS--SKP--CKPCTWCNLRSGSERKQLCTATQDTVCRCRAGTQPLDSY 119
C C P FY D + S P C PC C+ G+ +C + D AG
Sbjct: 371 CDRCRPLFYRDPLKTISDPYACIPCE-CD-PDGTISGGICVSHSDPALGSVAGQCLCKEN 428
Query: 120 KPGVDCAPCPPGHF--SPGDNQACKP 143
G C C P H+ S D C+P
Sbjct: 429 VEGAKCDQCKPNHYGLSATDPLGCQP 454
Score = 28.1 bits (61), Expect = 8.8
Identities = 26/99 (26%), Positives = 36/99 (36%), Gaps = 23/99 (23%)
Query: 45 ECRPGNGMVSRCSR-SQNTVCRP---------CGPGFYNDVVSSKPCKPCTWCNLRSGSE 94
+C P + S CSR C+P C G Y+ + C PC C+ +
Sbjct: 770 KCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYD--LGHHGCHPCH-CHPQG--- 823
Query: 95 RKQLCTATQDTVCRCRAGTQPLDSYKPGVDCAPCPPGHF 133
++DTVC G P G C C G+F
Sbjct: 824 -------SKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYF 855
>gi|22547121 tumor necrosis factor receptor superfamily, member 10c
precursor [Homo sapiens]
Length = 259
Score = 55.5 bits (132), Expect = 5e-08
Identities = 46/164 (28%), Positives = 71/164 (43%), Gaps = 20/164 (12%)
Query: 58 RSQNT-VCRPCGPGF-YNDVVSSKP-CKPCTWCNLRSGSERKQLCTATQDTVCRCRAGT- 113
RS++T C PC G Y + +++P C PCT C +S + K CT T+DTVC+C+ GT
Sbjct: 59 RSEHTGACNPCTEGVDYTNASNNEPSCFPCTVC--KSDQKHKSSCTMTRDTVCQCKEGTF 116
Query: 114 QPLDSYKPGVDCAPCPPGHFSPGDNQACKPWTNCTLA---GKHTLQPASNSSDAICEDRD 170
+ +S + C+ CP G + C W + G + + + +
Sbjct: 117 RNENSPEMCRKCSRCPSGEVQVSN---CTSWDDIQCVEEFGANATVETPAAEETMNTSPG 173
Query: 171 PPATQPQETQ----GPPA----RPITVQPTEAWPRTSQGPSTRP 206
PA +ET G PA +T P P + +T P
Sbjct: 174 TPAPAAEETMNTSPGTPAPAAEETMTTSPGTPAPAAEETMTTSP 217
Score = 37.4 bits (85), Expect = 0.014
Identities = 38/161 (23%), Positives = 60/161 (37%), Gaps = 14/161 (8%)
Query: 43 CHECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGSERKQLCTAT 102
C C+ S C+ +++TVC+ C G + + S + C+ C+ C SG + CT+
Sbjct: 88 CTVCKSDQKHKSSCTMTRDTVCQ-CKEGTFRNENSPEMCRKCSRC--PSGEVQVSNCTSW 144
Query: 103 QDTVCRCRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKPWTNCTLAGKHTLQPASNSS 162
D C G + PG +P + T T G T PA+ +
Sbjct: 145 DDIQCVEEFGANATVETPAAEETMNTSPGTPAPAAEE-----TMNTSPG--TPAPAAEET 197
Query: 163 DAICEDRDPPATQPQETQGP----PARPITVQPTEAWPRTS 199
PA + T P PA T+ + P +S
Sbjct: 198 MTTSPGTPAPAAEETMTTSPGTPAPAAEETMTTSPGTPASS 238
>gi|4507587 tumor necrosis factor receptor superfamily, member 7
precursor [Homo sapiens]
Length = 260
Score = 54.3 bits (129), Expect = 1e-07
Identities = 36/105 (34%), Positives = 46/105 (43%), Gaps = 8/105 (7%)
Query: 42 CCHECRPGNGMVSRCSRSQNTV-CRPCGPG--FYNDVVSSKPCKPCTWCNLRSGSERKQL 98
CC C PG +V C + + C PC PG F D + C+ C CN SG +
Sbjct: 39 CCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCN--SGLLVRN- 95
Query: 99 CTATQDTVCRCRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKP 143
CT T + C CR G Q D K +C P P + +QA P
Sbjct: 96 CTITANAECACRNGWQCRD--KECTECDPLPNPSLTARSSQALSP 138
>gi|7657039 tumor necrosis factor receptor superfamily, member 21
precursor [Homo sapiens]
Length = 655
Score = 50.1 bits (118), Expect = 2e-06
Identities = 48/185 (25%), Positives = 72/185 (38%), Gaps = 35/185 (18%)
Query: 15 ALLLLGLGLSTVTGL------HCVGDTYPSNDRC------CHECRPGNGMVSRCSRSQNT 62
+LLLLG LST T + +G TY DR C +C G + C+ +
Sbjct: 29 SLLLLGF-LSTTTAQPEQKASNLIG-TYRHVDRATGQVLTCDKCPAGTYVSEHCTNTSLR 86
Query: 63 VCRPCGPGFY----NDVVSSKPC-KPCTWCNLR-----SGSERKQLC---------TATQ 103
VC C G + N + C +PC W + + ++R+ C T
Sbjct: 87 VCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKLPCAALTDRECTCPPGMFQSNATCAP 146
Query: 104 DTVCRCRAGTQPLDSYKPGVDCAPCPPGHFS--PGDNQACKPWTNCTLAGKHTLQPASNS 161
TVC G + + V C C G FS P CK +T+C ++P +
Sbjct: 147 HTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKCKAYTDCLSQNLVVIKPGTKE 206
Query: 162 SDAIC 166
+D +C
Sbjct: 207 TDNVC 211
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 48.9 bits (115), Expect = 5e-06
Identities = 36/136 (26%), Positives = 51/136 (37%), Gaps = 21/136 (15%)
Query: 22 GLSTVTGLHCV-----GDTYPSNDRCCHECRPGNGMVSRC-SRSQNTVCRPCGPGFYNDV 75
G TV G CV G+ PS C G +C + C C GFY D
Sbjct: 837 GNPTVPGESCVPCDCSGNVDPSE---AGHCDSVTGECLKCLGNTDGAHCERCADGFYGDA 893
Query: 76 VSSKPCKPCTWCNLRSGSERKQLCTATQDTVCRCRAGTQPLDSYKPGVDCAPCPPGHFSP 135
V++K C+ C C+++ + VC G G C C G++
Sbjct: 894 VTAKNCRACE-CHVK----------GSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGL 942
Query: 136 GDNQACKPWTNCTLAG 151
C+P NC++AG
Sbjct: 943 DSGHGCRP-CNCSVAG 957
Score = 35.4 bits (80), Expect = 0.055
Identities = 35/122 (28%), Positives = 41/122 (33%), Gaps = 31/122 (25%)
Query: 44 HECRPGN----GMVSR-CSRSQNTVCRP---------CGPGFYNDVVSSKPCKPCTWCNL 89
H CRP N G VS C+ C P C GFY C PC
Sbjct: 946 HGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFY--AYQDGSCTPCD---- 999
Query: 90 RSGSERKQLCTATQDTVCRCRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKPWTNCTL 149
C TQ+T C G + GV C C GH+ C+ NC+L
Sbjct: 1000 ---------CPHTQNT-CDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQA-CNCSL 1048
Query: 150 AG 151
G
Sbjct: 1049 VG 1050
Score = 32.3 bits (72), Expect = 0.47
Identities = 41/148 (27%), Positives = 53/148 (35%), Gaps = 31/148 (20%)
Query: 43 CH----ECRPGNGMVSRCSRSQNTV-CRPCGPGFYNDVVSSKP--CKPCTWCNLRSGSER 95
CH EC +G+ C+ + V C C PGFY + P C+PC C L S
Sbjct: 744 CHGHAAECNV-HGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCA-CPLTIASNN 801
Query: 96 -KQLCTAT--QDTVCR-CRAG------TQPLDSY-----KPGVDCAPCP-PGHFSPGDNQ 139
C + VC C G + D Y PG C PC G+ P +
Sbjct: 802 FSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAG 861
Query: 140 ACKPWTNCTLAGKHTLQPASNSSDAICE 167
C T L+ N+ A CE
Sbjct: 862 HCDSVTG------ECLKCLGNTDGAHCE 883
>gi|23238194 tumor necrosis factor receptor superfamily, member 18
isoform 2 precursor [Homo sapiens]
Length = 255
Score = 48.9 bits (115), Expect = 5e-06
Identities = 43/158 (27%), Positives = 55/158 (34%), Gaps = 13/158 (8%)
Query: 49 GNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGSERKQLCTATQDTVCR 108
G G +RC R T C PG + S C C G CT + C
Sbjct: 42 GTGTDARCCRVHTTRCCRDYPG--EECCSEWDCM-CVQPEFHCGDP---CCTTCRHHPCP 95
Query: 109 CRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKPWTNCTLAGKH---TLQPASNSSDAI 165
G Q + G C C G FS G CKPWT+C + T + AS+ +
Sbjct: 96 PGQGVQSQGKFSFGFQCIDCASGTFSGGHEGHCKPWTDCCWRCRRRPKTPEAASSPRKSG 155
Query: 166 CEDRDPP----ATQPQETQGPPARPITVQPTEAWPRTS 199
DR T E PP P P+ P+ +
Sbjct: 156 ASDRQRRRGGWETCGCEPGRPPGPPTAASPSPGAPQAA 193
Score = 37.4 bits (85), Expect = 0.014
Identities = 32/118 (27%), Positives = 42/118 (35%), Gaps = 11/118 (9%)
Query: 31 CVGDTYPSNDRCC-----HECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCT 85
CV + D CC H C PG G+ S+ S C C G ++ CKP T
Sbjct: 74 CVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGH-CKPWT 132
Query: 86 WCNLRSGSERKQLCTATQDTVCRCRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKP 143
C R K A+ ++G + G + C PG PG A P
Sbjct: 133 DCCWRCRRRPKTPEAASSPR----KSGASDRQRRRGGWETCGCEPGR-PPGPPTAASP 185
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 48.5 bits (114), Expect = 6e-06
Identities = 33/109 (30%), Positives = 44/109 (40%), Gaps = 21/109 (19%)
Query: 43 CHECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGSERKQLCTAT 102
C C+PG + C C G++ D V +K C+PC CN +G ++C +
Sbjct: 886 CLICKPG---------TTGRYCELCADGYFGDAVDAKNCQPCR-CN--AGGSFSEVC-HS 932
Query: 103 QDTVCRCRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKPWTNCTLAG 151
Q C CRA Q G C C G F + C P NC G
Sbjct: 933 QTGQCECRANVQ-------GQRCDKCKAGTFGLQSARGCVP-CNCNSFG 973
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 48.5 bits (114), Expect = 6e-06
Identities = 33/109 (30%), Positives = 44/109 (40%), Gaps = 21/109 (19%)
Query: 43 CHECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGSERKQLCTAT 102
C C+PG + C C G++ D V +K C+PC CN +G ++C +
Sbjct: 886 CLICKPG---------TTGRYCELCADGYFGDAVDAKNCQPCR-CN--AGGSFSEVC-HS 932
Query: 103 QDTVCRCRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKPWTNCTLAG 151
Q C CRA Q G C C G F + C P NC G
Sbjct: 933 QTGQCECRANVQ-------GQRCDKCKAGTFGLQSARGCVP-CNCNSFG 973
>gi|4507575 tumor necrosis factor receptor 1 precursor [Homo
sapiens]
Length = 455
Score = 47.4 bits (111), Expect = 1e-05
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Query: 38 SNDRCCHECRPGNGMVSRC-SRSQNTVCRPCGPGFYNDVVSS-KPCKPCTWCNLRSGSER 95
+N CC +C G + + C Q+T CR C G + + + C C+ C G
Sbjct: 54 NNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVE 113
Query: 96 KQLCTATQDTVCRCR 110
CT +DTVC CR
Sbjct: 114 ISSCTVDRDTVCGCR 128
Score = 33.5 bits (75), Expect = 0.21
Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 43 CHECRPGNGMV--SRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGSERKQLCT 100
C +CR G V S C+ ++TVC C Y S + C C+L C
Sbjct: 102 CSKCRKEMGQVEISSCTVDRDTVCG-CRKNQYRHYWSENLFQ-CFNCSLCLNGTVHLSCQ 159
Query: 101 ATQDTVCRCRAG 112
Q+TVC C AG
Sbjct: 160 EKQNTVCTCHAG 171
>gi|68348711 tumor necrosis factor receptor superfamily, member 8
isoform 1 precursor [Homo sapiens]
Length = 595
Score = 47.0 bits (110), Expect = 2e-05
Identities = 49/181 (27%), Positives = 64/181 (35%), Gaps = 27/181 (14%)
Query: 41 RCCHECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGSERKQLCT 100
RCC+ C G +C + + C P +Y D + C C C+ R K C
Sbjct: 43 RCCYRCPMGLFPTQQCPQRPTDCRKQCEPDYYLD--EADRCTACVTCS-RDDLVEKTPCA 99
Query: 101 ATQDTVCRCRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKPWTNCTLAGKHTLQPASN 160
VC CR G S CA C P AG P +
Sbjct: 100 WNSSRVCECRPGM--FCSTSAVNSCARCFFHSVCP--------------AGMIVKFPGTA 143
Query: 161 SSDAICEDRDP---PA-TQPQETQGPPARPI-TVQPTEAWPRTSQGPSTRPVEVPGGRAV 215
+ +CE P PA P+ + P + I +PT P TS ST PV GG +
Sbjct: 144 QKNTVCEPASPGVSPACASPENCKEPSSGTIPQAKPTPVSPATSSA-STMPVR--GGTRL 200
Query: 216 A 216
A
Sbjct: 201 A 201
>gi|23510423 tumor necrosis factor receptor superfamily, member 6
isoform 3 precursor [Homo sapiens]
Length = 220
Score = 46.6 bits (109), Expect = 2e-05
Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 7/75 (9%)
Query: 36 YPSNDRCCHECRPGNGMVSR--CSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGS 93
+ S R C C G+G+ C+R+QNT CR C P F+ + + C PCT C
Sbjct: 97 FSSKCRRCRLCDEGHGLEVEINCTRTQNTKCR-CKPNFFCNSTVCEHCDPCTKCEHGIIK 155
Query: 94 ERKQLCTATQDTVCR 108
E CT T +T C+
Sbjct: 156 E----CTLTSNTKCK 166
Score = 42.0 bits (97), Expect = 6e-04
Identities = 26/72 (36%), Positives = 33/72 (45%), Gaps = 4/72 (5%)
Query: 43 CHE-CRPGNGMVSRCS-RSQNTVCRPCGPGF-YNDVVS-SKPCKPCTWCNLRSGSERKQL 98
CH+ C PG C+ C PC G Y D S C+ C C+ G E +
Sbjct: 59 CHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEIN 118
Query: 99 CTATQDTVCRCR 110
CT TQ+T CRC+
Sbjct: 119 CTRTQNTKCRCK 130
>gi|23510421 tumor necrosis factor receptor superfamily, member 6
isoform 2 precursor [Homo sapiens]
Length = 314
Score = 46.6 bits (109), Expect = 2e-05
Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 7/75 (9%)
Query: 36 YPSNDRCCHECRPGNGMVSR--CSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGS 93
+ S R C C G+G+ C+R+QNT CR C P F+ + + C PCT C
Sbjct: 97 FSSKCRRCRLCDEGHGLEVEINCTRTQNTKCR-CKPNFFCNSTVCEHCDPCTKCEHGIIK 155
Query: 94 ERKQLCTATQDTVCR 108
E CT T +T C+
Sbjct: 156 E----CTLTSNTKCK 166
Score = 42.0 bits (97), Expect = 6e-04
Identities = 26/72 (36%), Positives = 33/72 (45%), Gaps = 4/72 (5%)
Query: 43 CHE-CRPGNGMVSRCS-RSQNTVCRPCGPGF-YNDVVS-SKPCKPCTWCNLRSGSERKQL 98
CH+ C PG C+ C PC G Y D S C+ C C+ G E +
Sbjct: 59 CHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEIN 118
Query: 99 CTATQDTVCRCR 110
CT TQ+T CRC+
Sbjct: 119 CTRTQNTKCRCK 130
>gi|4507583 tumor necrosis factor receptor superfamily, member 6
isoform 1 precursor [Homo sapiens]
Length = 335
Score = 46.6 bits (109), Expect = 2e-05
Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 7/75 (9%)
Query: 36 YPSNDRCCHECRPGNGMVSR--CSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGS 93
+ S R C C G+G+ C+R+QNT CR C P F+ + + C PCT C
Sbjct: 97 FSSKCRRCRLCDEGHGLEVEINCTRTQNTKCR-CKPNFFCNSTVCEHCDPCTKCEHGIIK 155
Query: 94 ERKQLCTATQDTVCR 108
E CT T +T C+
Sbjct: 156 E----CTLTSNTKCK 166
Score = 42.0 bits (97), Expect = 6e-04
Identities = 26/72 (36%), Positives = 33/72 (45%), Gaps = 4/72 (5%)
Query: 43 CHE-CRPGNGMVSRCS-RSQNTVCRPCGPGF-YNDVVS-SKPCKPCTWCNLRSGSERKQL 98
CH+ C PG C+ C PC G Y D S C+ C C+ G E +
Sbjct: 59 CHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEIN 118
Query: 99 CTATQDTVCRCR 110
CT TQ+T CRC+
Sbjct: 119 CTRTQNTKCRCK 130
>gi|21361086 tumor necrosis factor receptor superfamily, member 10a
[Homo sapiens]
Length = 468
Score = 45.8 bits (107), Expect = 4e-05
Identities = 36/114 (31%), Positives = 52/114 (45%), Gaps = 16/114 (14%)
Query: 46 CRPGNGMVSRCSRSQNT-VCRPC--GPGFYNDVVSSKPCKPCTWCNLRSGSERKQLCTAT 102
C PG+ RS++ C C G G+ N + C PCT C +S E + CT T
Sbjct: 132 CPPGS------HRSEHPGACNRCTEGVGYTNASNNLFACLPCTAC--KSDEEERSPCTTT 183
Query: 103 QDTVCRCRAGTQPLD-SYKPGVDCA-PCPPGHFSPGDNQACKPWTNCTLAGKHT 154
++T C+C+ GT D S + C+ CP G D C PW++ K +
Sbjct: 184 RNTACQCKPGTFRNDNSAEMCRKCSRGCPRGMVKVKD---CTPWSDIECVHKES 234
Score = 33.9 bits (76), Expect = 0.16
Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 6/80 (7%)
Query: 32 VGDTYPSND--RC--CHECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWC 87
VG T SN+ C C C+ S C+ ++NT C+ C PG + + S++ C+ C+
Sbjct: 152 VGYTNASNNLFACLPCTACKSDEEERSPCTTTRNTACQ-CKPGTFRNDNSAEMCRKCS-R 209
Query: 88 NLRSGSERKQLCTATQDTVC 107
G + + CT D C
Sbjct: 210 GCPRGMVKVKDCTPWSDIEC 229
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.457
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,849,946
Number of Sequences: 37866
Number of extensions: 851805
Number of successful extensions: 4502
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 78
Number of HSP's successfully gapped in prelim test: 213
Number of HSP's that attempted gapping in prelim test: 3849
Number of HSP's gapped (non-prelim): 786
length of query: 277
length of database: 18,247,518
effective HSP length: 101
effective length of query: 176
effective length of database: 14,423,052
effective search space: 2538457152
effective search space used: 2538457152
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.