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Search of human proteins with 4507577
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507577 tumor necrosis factor receptor 2 precursor [Homo
sapiens]
(461 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507577 tumor necrosis factor receptor 2 precursor [Homo sapi... 955 0.0
gi|14790170 tumor necrosis factor receptor superfamily, member 6... 129 7e-30
gi|4507585 tumor necrosis factor receptor superfamily, member 6b... 129 7e-30
gi|148743793 osteoprotegerin precursor [Homo sapiens] 128 1e-29
gi|7657039 tumor necrosis factor receptor superfamily, member 21... 120 3e-27
gi|4505039 lymphotoxin beta receptor [Homo sapiens] 117 2e-26
gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens] 114 1e-25
gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens] 108 8e-24
gi|4507565 tumor necrosis factor receptor superfamily, member 11... 105 7e-23
gi|23200041 tumor necrosis factor receptor superfamily, member 1... 99 1e-20
gi|68348711 tumor necrosis factor receptor superfamily, member 8... 89 1e-17
gi|4507579 tumor necrosis factor receptor superfamily, member 4 ... 73 5e-13
gi|4505393 nerve growth factor receptor precursor [Homo sapiens] 70 5e-12
gi|5730095 tumor necrosis factor receptor superfamily, member 9 ... 62 8e-10
gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapi... 59 1e-08
gi|22547121 tumor necrosis factor receptor superfamily, member 1... 56 6e-08
gi|21361086 tumor necrosis factor receptor superfamily, member 1... 55 1e-07
gi|23510423 tumor necrosis factor receptor superfamily, member 6... 55 1e-07
gi|23510421 tumor necrosis factor receptor superfamily, member 6... 55 1e-07
gi|4507583 tumor necrosis factor receptor superfamily, member 6 ... 55 1e-07
gi|224494019 tumor necrosis factor receptor superfamily, member ... 54 3e-07
gi|224494026 tumor necrosis factor receptor superfamily, member ... 53 5e-07
gi|4507587 tumor necrosis factor receptor superfamily, member 7 ... 50 6e-06
gi|23200023 tumor necrosis factor receptor superfamily, member 2... 49 1e-05
gi|23200021 tumor necrosis factor receptor superfamily, member 2... 49 1e-05
gi|89142745 tumor necrosis factor receptor superfamily, member 2... 49 1e-05
gi|4507569 tumor necrosis factor receptor superfamily, member 25... 49 1e-05
gi|22547108 tumor necrosis factor receptor superfamily, member 1... 49 1e-05
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 48 2e-05
gi|11140823 X-linked ectodysplasin receptor [Homo sapiens] 48 2e-05
>gi|4507577 tumor necrosis factor receptor 2 precursor [Homo
sapiens]
Length = 461
Score = 955 bits (2468), Expect = 0.0
Identities = 461/461 (100%), Positives = 461/461 (100%)
Query: 1 MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPG 60
MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPG
Sbjct: 1 MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPG 60
Query: 61 QHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTC 120
QHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTC
Sbjct: 61 QHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTC 120
Query: 121 RPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICR 180
RPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICR
Sbjct: 121 RPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICR 180
Query: 181 PHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTS 240
PHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTS
Sbjct: 181 PHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTS 240
Query: 241 FLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKV 300
FLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKV
Sbjct: 241 FLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKV 300
Query: 301 PHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGE 360
PHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGE
Sbjct: 301 PHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGE 360
Query: 361 ARASTGSSDSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQ 420
ARASTGSSDSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQ
Sbjct: 361 ARASTGSSDSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQ 420
Query: 421 VPFSKEECAFRSQLETPETLLGSTEEKPLPLGVPDAGMKPS 461
VPFSKEECAFRSQLETPETLLGSTEEKPLPLGVPDAGMKPS
Sbjct: 421 VPFSKEECAFRSQLETPETLLGSTEEKPLPLGVPDAGMKPS 461
>gi|14790170 tumor necrosis factor receptor superfamily, member 6b
[Homo sapiens]
Length = 300
Score = 129 bits (323), Expect = 7e-30
Identities = 72/210 (34%), Positives = 102/210 (48%), Gaps = 18/210 (8%)
Query: 13 GLELWAAAHALPAQV---AFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTK 69
GL L ALPA + A A P R E ++ + C++C PG + C +
Sbjct: 8 GLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGER---LVCAQCPPGTFVQRPCRR 64
Query: 70 TSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALS 129
S T C C YTQ WN++ C C C + E +AC NR C CR G++
Sbjct: 65 DSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAG 124
Query: 130 KQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVA 189
C C PG GV PGT + + C+PC PGTFS ++SS++ C+PH+ C +
Sbjct: 125 ------FCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALG 178
Query: 190 ----IPGNASMDAVCTSTS--PTRSMAPGA 213
+PG++S D +CTS + P + PGA
Sbjct: 179 LALNVPGSSSHDTLCTSCTGFPLSTRVPGA 208
>gi|4507585 tumor necrosis factor receptor superfamily, member 6b
[Homo sapiens]
Length = 300
Score = 129 bits (323), Expect = 7e-30
Identities = 72/210 (34%), Positives = 102/210 (48%), Gaps = 18/210 (8%)
Query: 13 GLELWAAAHALPAQV---AFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTK 69
GL L ALPA + A A P R E ++ + C++C PG + C +
Sbjct: 8 GLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGER---LVCAQCPPGTFVQRPCRR 64
Query: 70 TSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALS 129
S T C C YTQ WN++ C C C + E +AC NR C CR G++
Sbjct: 65 DSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAG 124
Query: 130 KQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVA 189
C C PG GV PGT + + C+PC PGTFS ++SS++ C+PH+ C +
Sbjct: 125 ------FCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALG 178
Query: 190 ----IPGNASMDAVCTSTS--PTRSMAPGA 213
+PG++S D +CTS + P + PGA
Sbjct: 179 LALNVPGSSSHDTLCTSCTGFPLSTRVPGA 208
>gi|148743793 osteoprotegerin precursor [Homo sapiens]
Length = 401
Score = 128 bits (321), Expect = 1e-29
Identities = 66/166 (39%), Positives = 81/166 (48%), Gaps = 12/166 (7%)
Query: 45 YYDQTA--QMCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSS 102
+YD+ Q+ C KC PG + K CT TVC C D YT W+ ECL C C
Sbjct: 30 HYDEETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDHYYTDSWHTSDECLYCSPVCKE 89
Query: 103 DQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCK 162
Q Q C R NR+C C+ G Y + C R C PGFGV + GT + VCK
Sbjct: 90 LQYVKQECNRTHNRVCECKEGRYLEI------EFCLKHRSCPPGFGVVQAGTPERNTVCK 143
Query: 163 PCAPGTFSNTTSSTDICRPHQICNVVAI----PGNASMDAVCTSTS 204
C G FSN TSS CR H C+V + GNA+ D +C+ S
Sbjct: 144 RCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNATHDNICSGNS 189
>gi|7657039 tumor necrosis factor receptor superfamily, member 21
precursor [Homo sapiens]
Length = 655
Score = 120 bits (301), Expect = 3e-27
Identities = 92/305 (30%), Positives = 131/305 (42%), Gaps = 39/305 (12%)
Query: 52 MCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACT 111
+ C KC G + CT TS VC SC T+T+ N + +C C C +E C
Sbjct: 65 LTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKLPCA 124
Query: 112 REQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSN 171
+R CTC PG + + CAP C G+GV + GTET DV CK CA GTFS+
Sbjct: 125 ALTDRECTCPPGMF------QSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSD 178
Query: 172 TTSSTDICRPHQIC---NVVAI-PGNASMDAVC---TSTSPTRSMAPGAVHLPQPVSTRS 224
SS C+ + C N+V I PG D VC S S + S +PG P+P
Sbjct: 179 VPSSVMKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSSTSPSPGTAIFPRP----- 233
Query: 225 QHTQPTPEPSTAPSTSFLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIM 284
+H + PS S +P G + S+ V L + G V
Sbjct: 234 EHMETHEVPS-----STYVPKGMNSTESNSSAS--------VRPKVLSSIQEGTVPDNTS 280
Query: 285 TQVKKKPLCLQREAKVPHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPT 344
+ K+ + +P+L QGP +H+L PS ++ E S++ + + P
Sbjct: 281 SARGKEDV----NKTLPNLQV--VNHQQGPHHRHILKLLPSMEATGGEKSSTPI--KGPK 332
Query: 345 RNQPQ 349
R P+
Sbjct: 333 RGHPR 337
>gi|4505039 lymphotoxin beta receptor [Homo sapiens]
Length = 435
Score = 117 bits (293), Expect = 2e-26
Identities = 76/215 (35%), Positives = 99/215 (46%), Gaps = 29/215 (13%)
Query: 2 APVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCR--LREYYDQTAQMCCSKCSP 59
AP W L +GL AA A PYA E TCR +EYY+ ++CCS+C P
Sbjct: 9 APGLAWGPLVLGLFGLLAASQ---PQAVPPYASE-NQTCRDQEKEYYEPQHRICCSRCPP 64
Query: 60 GQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQV----ETQACTREQN 115
G + C++ DTVC +C +++Y + WN++ C C D V E CT ++
Sbjct: 65 GTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCR---PCDPVMGLEEIAPCTSKRK 121
Query: 116 RICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVV------CKPCAPGTF 169
C C+PG +CA E C C L C PG E D V C PC G F
Sbjct: 122 TQCRCQPGMFCAAWALE-CTHCELLSDCPPG-----TEAELKDEVGKGNNHCVPCKAGHF 175
Query: 170 SNTTSSTDICRPHQICN----VVAIPGNASMDAVC 200
NT+S + C+PH C V A PG A D C
Sbjct: 176 QNTSSPSARCQPHTRCENQGLVEAAPGTAQSDTTC 210
>gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]
Length = 277
Score = 114 bits (286), Expect = 1e-25
Identities = 66/187 (35%), Positives = 88/187 (47%), Gaps = 14/187 (7%)
Query: 30 TPYAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNW 89
T PEP + CR ++Y + CCS C PGQ CT+ ++T C C +S + WN
Sbjct: 16 TAVHPEPPTACREKQYLINS--QCCSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNR 73
Query: 90 VPECLSCGSRCSSD---QVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPG 146
C C + +V+ Q T E + ICTC GW+C E C C R C PG
Sbjct: 74 ETHCHQ-HKYCDPNLGLRVQ-QKGTSETDTICTCEEGWHCT---SEACESCVLHRSCSPG 128
Query: 147 FGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICN----VVAIPGNASMDAVCTS 202
FGV + T SD +C+PC G FSN +S+ + C P C VV G D VC
Sbjct: 129 FGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHPWTSCETKDLVVQQAGTNKTDVVCGP 188
Query: 203 TSPTRSM 209
R++
Sbjct: 189 QDRLRAL 195
>gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]
Length = 203
Score = 108 bits (271), Expect = 8e-24
Identities = 58/155 (37%), Positives = 78/155 (50%), Gaps = 10/155 (6%)
Query: 30 TPYAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNW 89
T PEP + CR ++Y + CCS C PGQ CT+ ++T C C +S + WN
Sbjct: 16 TAVHPEPPTACREKQYLINS--QCCSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNR 73
Query: 90 VPECLSCGSRCSSD---QVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPG 146
C C + +V+ Q T E + ICTC GW+C E C C R C PG
Sbjct: 74 ETHCHQ-HKYCDPNLGLRVQ-QKGTSETDTICTCEEGWHCT---SEACESCVLHRSCSPG 128
Query: 147 FGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRP 181
FGV + T SD +C+PC G FSN +S+ + C P
Sbjct: 129 FGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHP 163
Score = 36.6 bits (83), Expect = 0.049
Identities = 18/64 (28%), Positives = 28/64 (43%), Gaps = 5/64 (7%)
Query: 143 CRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNV-----VAIPGNASMD 197
C+PG + TE ++ C PC F +T + C H+ C+ V G + D
Sbjct: 41 CQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCDPNLGLRVQQKGTSETD 100
Query: 198 AVCT 201
+CT
Sbjct: 101 TICT 104
>gi|4507565 tumor necrosis factor receptor superfamily, member 11a
precursor [Homo sapiens]
Length = 616
Score = 105 bits (263), Expect = 7e-23
Identities = 64/186 (34%), Positives = 84/186 (45%), Gaps = 13/186 (6%)
Query: 40 CRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSR 99
C ++Y+ + CC+KC PG++ CT TSD+VC C Y WN +CL
Sbjct: 34 CTSEKHYEHLGR-CCNKCEPGKYMSSKCTTTSDSVCLPCGPDEYLDSWNEEDKCL-LHKV 91
Query: 100 CSSDQ--VETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETS 157
C + + V A R C C G++ + + C C +C PG G P
Sbjct: 92 CDTGKALVAVVAGNSTTPRRCACTAGYHWS----QDCECCRRNTECAPGLGAQHPLQLNK 147
Query: 158 DVVCKPCAPGTFSNTTSSTDICRPHQICNV----VAIPGNASMDAVCTSTSPTRSMAPGA 213
D VCKPC G FS+ SSTD CRP C V G DAVC+S+ P R P
Sbjct: 148 DTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGKRVEHHGTEKSDAVCSSSLPARK-PPNE 206
Query: 214 VHLPQP 219
H+ P
Sbjct: 207 PHVYLP 212
>gi|23200041 tumor necrosis factor receptor superfamily, member 14
precursor [Homo sapiens]
Length = 283
Score = 98.6 bits (244), Expect = 1e-20
Identities = 53/146 (36%), Positives = 70/146 (47%), Gaps = 16/146 (10%)
Query: 32 YAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVP 91
YAP S C+ EY CC KCSPG K C + + TVC+ C TY N +
Sbjct: 35 YAPALPS-CKEDEY--PVGSECCPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLS 91
Query: 92 ECLSC-------GSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCR 144
+CL C G R S + C+R +N +C C PG +C + + C C
Sbjct: 92 KCLQCQMCDPAMGLRASRN------CSRTENAVCGCSPGHFCIVQDGDHCAACRAYATSS 145
Query: 145 PGFGVARPGTETSDVVCKPCAPGTFS 170
PG V + GTE+ D +C+ C PGTFS
Sbjct: 146 PGQRVQKGGTESQDTLCQNCPPGTFS 171
Score = 39.3 bits (90), Expect = 0.008
Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 2/50 (4%)
Query: 137 CAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICN 186
C P KC PG+ V E + VC+PC PGT+ + C Q+C+
Sbjct: 53 CCP--KCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCD 100
>gi|68348711 tumor necrosis factor receptor superfamily, member 8
isoform 1 precursor [Homo sapiens]
Length = 595
Score = 88.6 bits (218), Expect = 1e-17
Identities = 67/246 (27%), Positives = 88/246 (35%), Gaps = 17/246 (6%)
Query: 11 AVGLELWAAAHALPAQVAFTPYAPEPGSTCRLR--EYYDQTAQMCCSKCSPGQHAKVFCT 68
A+GL A A P F TC YYD+ + CC +C G C
Sbjct: 7 ALGLLFLGALRAFPQDRPFE-------DTCHGNPSHYYDKAVRRCCYRCPMGLFPTQQCP 59
Query: 69 KTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCAL 128
+ CE Y + C++C D VE C +R+C CRPG +C+
Sbjct: 60 QRPTDCRKQCEPDYYLDEADRCTACVTCSR---DDLVEKTPCAWNSSRVCECRPGMFCST 116
Query: 129 SKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVV 188
S C C C G V PGT + VC+P +PG S + P
Sbjct: 117 SAVNSCARCFFHSVCPAGMIVKFPGTAQKNTVCEPASPGVSPACASPENCKEPSSGTIPQ 176
Query: 189 AIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTS-FLLPMGP 247
A P S ST P R G L Q +++ +P PS+ L P P
Sbjct: 177 AKPTPVSPATSSASTMPVR----GGTRLAQEAASKLTRAPDSPSSVGRPSSDPGLSPTQP 232
Query: 248 SPPAEG 253
P G
Sbjct: 233 CPEGSG 238
Score = 55.8 bits (133), Expect = 8e-08
Identities = 81/320 (25%), Positives = 112/320 (35%), Gaps = 56/320 (17%)
Query: 59 PGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRIC 118
PG C + S CE Y C+SC D VE C +R C
Sbjct: 225 PGLSPTQPCPEGSGDCRKQCEPDYYLDEAGRCTACVSCSR---DDLVEKTPCAWNSSRTC 281
Query: 119 TCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDI 178
CRPG CA S C P C A T+ D+ K +TT
Sbjct: 282 ECRPGMICATSATNSRARCVPYPIC-----AAETVTKPQDMAEK--------DTTFEAPP 328
Query: 179 CRPHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPS 238
CN G A STSPT+S+ SQ ++ P P++A
Sbjct: 329 LGTQPDCNPTPENGEAP-----ASTSPTQSLL-----------VDSQASKTLPIPTSA-- 370
Query: 239 TSFLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREA 298
P A STG L G ++ L L+++ + ++ + C +R
Sbjct: 371 ----------PVALSSTGKPVLDAGPVLFWVILVLVVVVGSSAFLLCH---RRACRKRIR 417
Query: 299 KVPHL--PADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEA- 355
+ HL P T P+ + L+ + P SS+ L S AS + A R P +E
Sbjct: 418 QKLHLCYPVQ----TSQPKLE-LVDSRPRRSSTQLRSGASVTEPVAEERGLMSQPLMETC 472
Query: 356 -SGAGEARASTGSSDSSPGG 374
S S D+SP G
Sbjct: 473 HSVGAAYLESLPLQDASPAG 492
>gi|4507579 tumor necrosis factor receptor superfamily, member 4
precursor [Homo sapiens]
Length = 277
Score = 73.2 bits (178), Expect = 5e-13
Identities = 64/230 (27%), Positives = 86/230 (37%), Gaps = 44/230 (19%)
Query: 53 CCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVP--ECLSCGSRCSSDQVETQAC 110
CC +C PG C+++ +TVC C Y + + P C C R S++ Q C
Sbjct: 42 CCHECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGSER--KQLC 99
Query: 111 TREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFS 170
T Q+ +C CR G PL +PG V C PC PG FS
Sbjct: 100 TATQDTVCRCRAG-------------TQPLDSYKPG------------VDCAPCPPGHFS 134
Query: 171 NTTSSTDICRPHQICNVVA----IPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQH 226
C+P C + P + S DA+C P + P P Q
Sbjct: 135 --PGDNQACKPWTNCTLAGKHTLQPASNSSDAICEDRDPPATQ-PQETQGPPARPITVQP 191
Query: 227 TQPTPEPSTAPSTSFLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLII 276
T+ P S PST P G L +GL++G+ LG L I
Sbjct: 192 TEAWPRTSQGPSTR------PVEVPGGRAVAAILGLGLVLGL--LGPLAI 233
>gi|4505393 nerve growth factor receptor precursor [Homo sapiens]
Length = 427
Score = 69.7 bits (169), Expect = 5e-12
Identities = 52/188 (27%), Positives = 75/188 (39%), Gaps = 19/188 (10%)
Query: 53 CCSKCSPGQHAKVFCTKTSDTVCDSCEDS-TYTQLWNWVPECLSCGSRCSSDQVETQACT 111
CC C+ G+ C + TVC+ C DS T++ + + C C + C Q + C
Sbjct: 43 CCKACNLGEGVAQPCG-ANQTVCEPCLDSVTFSDVVSATEPCKPC-TECVGLQSMSAPCV 100
Query: 112 REQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSN 171
+ +C C G+Y + E C R C G G+ + + VC+ C GT+S+
Sbjct: 101 EADDAVCRCAYGYY----QDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSD 156
Query: 172 TTSSTDICRPHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTP 231
+ D C P +C D TR +P TRS T P
Sbjct: 157 EANHVDPCLPCTVCE----------DTERQLRECTRWADAECEEIPGRWITRS--TPPEG 204
Query: 232 EPSTAPST 239
STAPST
Sbjct: 205 SDSTAPST 212
Score = 55.1 bits (131), Expect = 1e-07
Identities = 33/103 (32%), Positives = 43/103 (41%), Gaps = 4/103 (3%)
Query: 40 CRLREYYDQTAQMC--CSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCG 97
C Y D+T C C C G C +TVC+ C D TY+ N V CL C
Sbjct: 109 CAYGYYQDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPC- 167
Query: 98 SRCSSDQVETQACTREQNRICTCRPG-WYCALSKQEGCRLCAP 139
+ C + + + CTR + C PG W + EG AP
Sbjct: 168 TVCEDTERQLRECTRWADAECEEIPGRWITRSTPPEGSDSTAP 210
>gi|5730095 tumor necrosis factor receptor superfamily, member 9
precursor [Homo sapiens]
Length = 255
Score = 62.4 bits (150), Expect = 8e-10
Identities = 48/180 (26%), Positives = 72/180 (40%), Gaps = 26/180 (14%)
Query: 54 CSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTRE 113
CS C G FC + +C C ++++ C C +C + C+
Sbjct: 28 CSNCPAG----TFCDNNRNQICSPCPPNSFSSAGGQ-RTCDIC-RQCKGVFRTRKECSST 81
Query: 114 QNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTT 173
N C C PG++C GC +C + C+ G + + G CK C GTF++
Sbjct: 82 SNAECDCTPGFHCL---GAGCSMCE--QDCKQGQELTKKG-------CKDCCFGTFND-- 127
Query: 174 SSTDICRPHQICNV----VAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQP 229
ICRP C++ V + G D VC SP ++PGA + P R P
Sbjct: 128 QKRGICRPWTNCSLDGKSVLVNGTKERDVVC-GPSPA-DLSPGASSVTPPAPAREPGHSP 185
>gi|4507575 tumor necrosis factor receptor 1 precursor [Homo
sapiens]
Length = 455
Score = 58.5 bits (140), Expect = 1e-08
Identities = 48/165 (29%), Positives = 68/165 (41%), Gaps = 20/165 (12%)
Query: 38 STCRLREY-YDQTAQMCCSKCSPGQHAKVFCT-KTSDTVCDSCEDSTYTQLWNWVPECLS 95
S C +Y + Q +CC+KC G + C DT C CE ++T N + CLS
Sbjct: 42 SVCPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLS 101
Query: 96 CGSRCSSD--QVETQACTREQNRICTCRPG-----WYCALSKQEGCRLCAPLRKCRPGFG 148
C S+C + QVE +CT +++ +C CR W L + C LC
Sbjct: 102 C-SKCRKEMGQVEISSCTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCL-------NGT 153
Query: 149 VARPGTETSDVVCKPCAPGTF--SNTTSSTDICRPHQICNVVAIP 191
V E + VC C G F N S C+ C + +P
Sbjct: 154 VHLSCQEKQNTVC-TCHAGFFLRENECVSCSNCKKSLECTKLCLP 197
Score = 49.3 bits (116), Expect = 7e-06
Identities = 38/122 (31%), Positives = 54/122 (44%), Gaps = 15/122 (12%)
Query: 34 PEPG--STCRLREYYDQTAQ-------MCCSKCSP--GQHAKVFCTKTSDTVCDSCEDST 82
P PG + CR E TA + CSKC GQ CT DTVC C +
Sbjct: 73 PGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTVC-GCRKNQ 131
Query: 83 YTQLWNW-VPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLR 141
Y W+ + +C +C S C + V +C +QN +CTC G++ ++ C C
Sbjct: 132 YRHYWSENLFQCFNC-SLCLNGTVHL-SCQEKQNTVCTCHAGFFLRENECVSCSNCKKSL 189
Query: 142 KC 143
+C
Sbjct: 190 EC 191
>gi|22547121 tumor necrosis factor receptor superfamily, member 10c
precursor [Homo sapiens]
Length = 259
Score = 56.2 bits (134), Expect = 6e-08
Identities = 52/212 (24%), Positives = 80/212 (37%), Gaps = 25/212 (11%)
Query: 75 CDSCEDST-YTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEG 133
C+ C + YT N P C C + C SDQ +CT ++ +C C+ G + + E
Sbjct: 66 CNPCTEGVDYTNASNNEPSCFPC-TVCKSDQKHKSSCTMTRDTVCQCKEGTFRNENSPEM 124
Query: 134 CRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVAIPGN 193
CR C+ +C G T D+ C +N T T N
Sbjct: 125 CRKCS---RCPSGEVQVSNCTSWDDI---QCVEEFGANATVETPAAEETM---------N 169
Query: 194 ASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQP-TPEPSTAPSTSFLLPMGPSPPAE 252
S + T + +PG P P + + T P TP P+ A T P P+P AE
Sbjct: 170 TSPGTPAPAAEETMNTSPGT---PAPAAEETMTTSPGTPAPA-AEETMTTSPGTPAPAAE 225
Query: 253 GSTGDFALPVGLIVGVTALGLLIIGVVNCVIM 284
+ G L I+G++ +++
Sbjct: 226 ET---MTTSPGTPASSHYLSCTIVGIIVLIVL 254
Score = 40.4 bits (93), Expect = 0.003
Identities = 23/58 (39%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Query: 54 CSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACT 111
C+ C Q K CT T DTVC C++ T+ N C C SRC S +V+ CT
Sbjct: 88 CTVCKSDQKHKSSCTMTRDTVC-QCKEGTFRN-ENSPEMCRKC-SRCPSGEVQVSNCT 142
>gi|21361086 tumor necrosis factor receptor superfamily, member 10a
[Homo sapiens]
Length = 468
Score = 55.5 bits (132), Expect = 1e-07
Identities = 34/106 (32%), Positives = 46/106 (43%), Gaps = 9/106 (8%)
Query: 57 CSPGQHAKVFCTKTSDTVCDSCEDST-YTQLWNWVPECLSCGSRCSSDQVETQACTREQN 115
C PG H C+ C + YT N + CL C + C SD+ E CT +N
Sbjct: 132 CPPGSHRS-----EHPGACNRCTEGVGYTNASNNLFACLPC-TACKSDEEERSPCTTTRN 185
Query: 116 RICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVC 161
C C+PG + + E CR C+ R C G + T SD+ C
Sbjct: 186 TACQCKPGTFRNDNSAEMCRKCS--RGCPRGMVKVKDCTPWSDIEC 229
Score = 31.6 bits (70), Expect = 1.6
Identities = 16/58 (27%), Positives = 24/58 (41%), Gaps = 2/58 (3%)
Query: 54 CSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACT 111
C+ C + + CT T +T C C+ T+ N C C C V+ + CT
Sbjct: 167 CTACKSDEEERSPCTTTRNTAC-QCKPGTFRN-DNSAEMCRKCSRGCPRGMVKVKDCT 222
>gi|23510423 tumor necrosis factor receptor superfamily, member 6
isoform 3 precursor [Homo sapiens]
Length = 220
Score = 55.1 bits (131), Expect = 1e-07
Identities = 35/115 (30%), Positives = 49/115 (42%), Gaps = 8/115 (6%)
Query: 51 QMCCSKCSPGQHAKVFCTKTSDTV-CDSCEDST-YTQLWNWVPECLSCGSRCSSDQVETQ 108
Q C C PG+ CT D C C++ YT ++ +C C +E +
Sbjct: 57 QFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVE 116
Query: 109 A-CTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCK 162
CTR QN C C+P ++C C C P KC G+ + T TS+ CK
Sbjct: 117 INCTRTQNTKCRCKPNFFC---NSTVCEHCDPCTKCE--HGIIKECTLTSNTKCK 166
>gi|23510421 tumor necrosis factor receptor superfamily, member 6
isoform 2 precursor [Homo sapiens]
Length = 314
Score = 55.1 bits (131), Expect = 1e-07
Identities = 35/115 (30%), Positives = 49/115 (42%), Gaps = 8/115 (6%)
Query: 51 QMCCSKCSPGQHAKVFCTKTSDTV-CDSCEDST-YTQLWNWVPECLSCGSRCSSDQVETQ 108
Q C C PG+ CT D C C++ YT ++ +C C +E +
Sbjct: 57 QFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVE 116
Query: 109 A-CTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCK 162
CTR QN C C+P ++C C C P KC G+ + T TS+ CK
Sbjct: 117 INCTRTQNTKCRCKPNFFC---NSTVCEHCDPCTKCE--HGIIKECTLTSNTKCK 166
>gi|4507583 tumor necrosis factor receptor superfamily, member 6
isoform 1 precursor [Homo sapiens]
Length = 335
Score = 55.1 bits (131), Expect = 1e-07
Identities = 35/115 (30%), Positives = 49/115 (42%), Gaps = 8/115 (6%)
Query: 51 QMCCSKCSPGQHAKVFCTKTSDTV-CDSCEDST-YTQLWNWVPECLSCGSRCSSDQVETQ 108
Q C C PG+ CT D C C++ YT ++ +C C +E +
Sbjct: 57 QFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVE 116
Query: 109 A-CTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCK 162
CTR QN C C+P ++C C C P KC G+ + T TS+ CK
Sbjct: 117 INCTRTQNTKCRCKPNFFC---NSTVCEHCDPCTKCE--HGIIKECTLTSNTKCK 166
>gi|224494019 tumor necrosis factor receptor superfamily, member 10b
isoform 1 precursor [Homo sapiens]
Length = 440
Score = 53.9 bits (128), Expect = 3e-07
Identities = 39/117 (33%), Positives = 50/117 (42%), Gaps = 17/117 (14%)
Query: 57 CSPGQHAKVFCTKTSDTVCDSCE-DSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQN 115
C PG H C SC+ Y+ WN + CL C +RC S +VE CT +N
Sbjct: 81 CPPGHHIS-----EDGRDCISCKYGQDYSTHWNDLLFCLRC-TRCDSGEVELSPCTTTRN 134
Query: 116 RICTCRPGWYCALSKQEGCRLCAPLRKCRPGF--GVARPG--TETSDVVCKPCAPGT 168
+C C G + E C RKCR G G+ + G T SD+ C GT
Sbjct: 135 TVCQCEEGTFREEDSPEMC------RKCRTGCPRGMVKVGDCTPWSDIECVHKESGT 185
Score = 35.4 bits (80), Expect = 0.11
Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 4/59 (6%)
Query: 54 CSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPE-CLSCGSRCSSDQVETQACT 111
C++C G+ CT T +TVC CE+ T+ + PE C C + C V+ CT
Sbjct: 116 CTRCDSGEVELSPCTTTRNTVC-QCEEGTFRE--EDSPEMCRKCRTGCPRGMVKVGDCT 171
>gi|224494026 tumor necrosis factor receptor superfamily, member 10b
isoform 2 precursor [Homo sapiens]
Length = 411
Score = 53.1 bits (126), Expect = 5e-07
Identities = 37/110 (33%), Positives = 48/110 (43%), Gaps = 17/110 (15%)
Query: 57 CSPGQHAKVFCTKTSDTVCDSCE-DSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQN 115
C PG H C SC+ Y+ WN + CL C +RC S +VE CT +N
Sbjct: 81 CPPGHHIS-----EDGRDCISCKYGQDYSTHWNDLLFCLRC-TRCDSGEVELSPCTTTRN 134
Query: 116 RICTCRPGWYCALSKQEGCRLCAPLRKCRPGF--GVARPG--TETSDVVC 161
+C C G + E C RKCR G G+ + G T SD+ C
Sbjct: 135 TVCQCEEGTFREEDSPEMC------RKCRTGCPRGMVKVGDCTPWSDIEC 178
Score = 35.4 bits (80), Expect = 0.11
Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 4/59 (6%)
Query: 54 CSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPE-CLSCGSRCSSDQVETQACT 111
C++C G+ CT T +TVC CE+ T+ + PE C C + C V+ CT
Sbjct: 116 CTRCDSGEVELSPCTTTRNTVC-QCEEGTFRE--EDSPEMCRKCRTGCPRGMVKVGDCT 171
>gi|4507587 tumor necrosis factor receptor superfamily, member 7
precursor [Homo sapiens]
Length = 260
Score = 49.7 bits (117), Expect = 6e-06
Identities = 35/109 (32%), Positives = 48/109 (44%), Gaps = 9/109 (8%)
Query: 34 PEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTV-CDSCEDS-TYTQLWNWVP 91
P P S C R Y+ Q ++CC C PG C + CD C +++ + P
Sbjct: 22 PAPKS-CPERHYWAQ-GKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRP 79
Query: 92 ECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPL 140
C SC C+S + + CT N C CR GW C + + C C PL
Sbjct: 80 HCESC-RHCNSGLL-VRNCTITANAECACRNGWQC---RDKECTECDPL 123
>gi|23200023 tumor necrosis factor receptor superfamily, member 25
isoform 3 precursor [Homo sapiens]
Length = 380
Score = 48.9 bits (115), Expect = 1e-05
Identities = 33/137 (24%), Positives = 53/137 (38%), Gaps = 11/137 (8%)
Query: 44 EYYDQTAQMCCSKCSPGQHAKVFCTKT-SDTVCDSCEDSTYTQLWNW----VPECLSCGS 98
+++ + CC C G + K CT+ ++ C C T+ N C +C
Sbjct: 38 DFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDE 97
Query: 99 RCSSDQVETQACTREQNRICTCRPGWY--CALSK--QEGCRLCAPLRKCRPGFGVARPGT 154
+ S QV + C+ + C C+PGW+ C +S+ C P C R
Sbjct: 98 QAS--QVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLC 155
Query: 155 ETSDVVCKPCAPGTFSN 171
D C C PG + +
Sbjct: 156 SRRDTDCGTCLPGFYEH 172
>gi|23200021 tumor necrosis factor receptor superfamily, member 25
isoform 1 precursor [Homo sapiens]
Length = 426
Score = 48.9 bits (115), Expect = 1e-05
Identities = 33/137 (24%), Positives = 53/137 (38%), Gaps = 11/137 (8%)
Query: 44 EYYDQTAQMCCSKCSPGQHAKVFCTKT-SDTVCDSCEDSTYTQLWNW----VPECLSCGS 98
+++ + CC C G + K CT+ ++ C C T+ N C +C
Sbjct: 38 DFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDE 97
Query: 99 RCSSDQVETQACTREQNRICTCRPGWY--CALSK--QEGCRLCAPLRKCRPGFGVARPGT 154
+ S QV + C+ + C C+PGW+ C +S+ C P C R
Sbjct: 98 QAS--QVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLC 155
Query: 155 ETSDVVCKPCAPGTFSN 171
D C C PG + +
Sbjct: 156 SRRDTDCGTCLPGFYEH 172
>gi|89142745 tumor necrosis factor receptor superfamily, member 25
isoform 12 precursor [Homo sapiens]
Length = 181
Score = 48.9 bits (115), Expect = 1e-05
Identities = 33/137 (24%), Positives = 53/137 (38%), Gaps = 11/137 (8%)
Query: 44 EYYDQTAQMCCSKCSPGQHAKVFCTKT-SDTVCDSCEDSTYTQLWNW----VPECLSCGS 98
+++ + CC C G + K CT+ ++ C C T+ N C +C
Sbjct: 38 DFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDE 97
Query: 99 RCSSDQVETQACTREQNRICTCRPGWY--CALSK--QEGCRLCAPLRKCRPGFGVARPGT 154
+ S QV + C+ + C C+PGW+ C +S+ C P C R
Sbjct: 98 QAS--QVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLC 155
Query: 155 ETSDVVCKPCAPGTFSN 171
D C C PG + +
Sbjct: 156 SRRDTDCGTCLPGFYEH 172
>gi|4507569 tumor necrosis factor receptor superfamily, member 25
isoform 2 precursor [Homo sapiens]
Length = 417
Score = 48.9 bits (115), Expect = 1e-05
Identities = 33/137 (24%), Positives = 53/137 (38%), Gaps = 11/137 (8%)
Query: 44 EYYDQTAQMCCSKCSPGQHAKVFCTKT-SDTVCDSCEDSTYTQLWNW----VPECLSCGS 98
+++ + CC C G + K CT+ ++ C C T+ N C +C
Sbjct: 38 DFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDE 97
Query: 99 RCSSDQVETQACTREQNRICTCRPGWY--CALSK--QEGCRLCAPLRKCRPGFGVARPGT 154
+ S QV + C+ + C C+PGW+ C +S+ C P C R
Sbjct: 98 QAS--QVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLC 155
Query: 155 ETSDVVCKPCAPGTFSN 171
D C C PG + +
Sbjct: 156 SRRDTDCGTCLPGFYEH 172
>gi|22547108 tumor necrosis factor receptor superfamily, member 10d
precursor [Homo sapiens]
Length = 386
Score = 48.5 bits (114), Expect = 1e-05
Identities = 31/108 (28%), Positives = 44/108 (40%), Gaps = 9/108 (8%)
Query: 56 KCSPGQHAKVFCTKTSDTVCDSCEDST-YTQLWNWVPECLSCGSRCSSDQVETQACTREQ 114
+C G H + C+ C + YT N +P CL C + C S Q +CT +
Sbjct: 82 ECPAGSHRSEYTG-----ACNPCTEGVDYTIASNNLPSCLLC-TVCKSGQTNKSSCTTTR 135
Query: 115 NRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCK 162
+ +C C G + + E CR C C G T SD+ CK
Sbjct: 136 DTVCQCEKGSFQDKNSPEMCRTCR--TGCPRGMVKVSNCTPRSDIKCK 181
Score = 40.8 bits (94), Expect = 0.003
Identities = 23/67 (34%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Query: 52 MCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACT 111
+ C+ C GQ K CT T DTVC CE ++ Q N C +C + C V+ CT
Sbjct: 116 LLCTVCKSGQTNKSSCTTTRDTVC-QCEKGSF-QDKNSPEMCRTCRTGCPRGMVKVSNCT 173
Query: 112 REQNRIC 118
+ C
Sbjct: 174 PRSDIKC 180
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 47.8 bits (112), Expect = 2e-05
Identities = 38/151 (25%), Positives = 58/151 (38%)
Query: 306 DKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGEARAST 365
DKA+ Q ++ ++ SS SSS SS+S+ + G G G S
Sbjct: 2545 DKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSA 2604
Query: 366 GSSDSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQVPFSK 425
SS ++ + + + + SSS SS SS +SS+ + SS S S S
Sbjct: 2605 ASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2664
Query: 426 EECAFRSQLETPETLLGSTEEKPLPLGVPDA 456
+ S + + E P P P A
Sbjct: 2665 SSSSSSSTTDEDSSCSSDDEAAPAPTAGPSA 2695
Score = 37.7 bits (86), Expect = 0.022
Identities = 34/117 (29%), Positives = 51/117 (43%), Gaps = 23/117 (19%)
Query: 323 APSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGEARASTGSSDSSPGGHGTQVNVT 382
+P+SSSSS SS+S+ + + + +S + + +S+ SS SS
Sbjct: 2611 SPASSSSSSSSSSSS------SSSSSSSSSSSSSSSSSSSSSSSSSSSS----------- 2653
Query: 383 CIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQVPFSKEECAFRSQLETPET 439
SSS SS SS +SS+ TD S S DE P + ++ L T T
Sbjct: 2654 ------SSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKAT 2704
Score = 30.0 bits (66), Expect = 4.6
Identities = 56/245 (22%), Positives = 89/245 (36%), Gaps = 40/245 (16%)
Query: 192 GNASMDAVCTSTSPTRSMAPGAVHLP-QPVSTRSQHTQPTP---EPSTAPSTSFLLPMGP 247
GN + + T + S PG+ P +PV R++ + P +PS AP P P
Sbjct: 2351 GNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCP-AP 2409
Query: 248 SPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKVPHLPADK 307
P AE +L ++ + A + KK + AK P P ++
Sbjct: 2410 EPFAELPAPATSLAPAPLITMPAT------------RPKPKKARAAEESGAKGPRRPGEE 2457
Query: 308 AR--------GTQGPEQQH-----LLITAPSSSSSSLESSASALDRRAPTR--NQPQAPG 352
A G P+ + LL P + S +L P ++P+AP
Sbjct: 2458 AELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPW 2517
Query: 353 VEAS--------GAGEARASTGSSDSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASST 404
+A+ G G +G+ S Q + SSS SS SS +SS+
Sbjct: 2518 PKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSS 2577
Query: 405 MGDTD 409
+T+
Sbjct: 2578 GSETE 2582
>gi|11140823 X-linked ectodysplasin receptor [Homo sapiens]
Length = 297
Score = 47.8 bits (112), Expect = 2e-05
Identities = 38/131 (29%), Positives = 52/131 (39%), Gaps = 24/131 (18%)
Query: 40 CRLREYYDQTAQ-MCCSKCSPGQHAKVFCT--KTSDTVCDSCEDSTYTQLWNWVPECLSC 96
C+ EY+DQ + + C +C PGQ C + D C +C Y W C SC
Sbjct: 3 CQENEYWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGH-HRCQSC 61
Query: 97 GSRCSSDQVETQACTREQNRIC-TCRPGWY-----CALSKQEGCRLCAPLRKCRPGFGVA 150
+ ++V+ CT N +C C P +Y L QE C P K P
Sbjct: 62 ITCAVINRVQKVNCTATSNAVCGDCLPRFYRKTRIGGLQDQE----CIPCTKQTP----- 112
Query: 151 RPGTETSDVVC 161
TS+V C
Sbjct: 113 -----TSEVQC 118
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.127 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,696,913
Number of Sequences: 37866
Number of extensions: 1268429
Number of successful extensions: 7929
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 75
Number of HSP's successfully gapped in prelim test: 339
Number of HSP's that attempted gapping in prelim test: 6548
Number of HSP's gapped (non-prelim): 1514
length of query: 461
length of database: 18,247,518
effective HSP length: 106
effective length of query: 355
effective length of database: 14,233,722
effective search space: 5052971310
effective search space used: 5052971310
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.