Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 4507577

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507577 tumor necrosis factor receptor 2 precursor [Homo
sapiens]
         (461 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507577 tumor necrosis factor receptor 2 precursor [Homo sapi...   955   0.0  
gi|14790170 tumor necrosis factor receptor superfamily, member 6...   129   7e-30
gi|4507585 tumor necrosis factor receptor superfamily, member 6b...   129   7e-30
gi|148743793 osteoprotegerin precursor [Homo sapiens]                 128   1e-29
gi|7657039 tumor necrosis factor receptor superfamily, member 21...   120   3e-27
gi|4505039 lymphotoxin beta receptor [Homo sapiens]                   117   2e-26
gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]            114   1e-25
gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]           108   8e-24
gi|4507565 tumor necrosis factor receptor superfamily, member 11...   105   7e-23
gi|23200041 tumor necrosis factor receptor superfamily, member 1...    99   1e-20
gi|68348711 tumor necrosis factor receptor superfamily, member 8...    89   1e-17
gi|4507579 tumor necrosis factor receptor superfamily, member 4 ...    73   5e-13
gi|4505393 nerve growth factor receptor precursor [Homo sapiens]       70   5e-12
gi|5730095 tumor necrosis factor receptor superfamily, member 9 ...    62   8e-10
gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapi...    59   1e-08
gi|22547121 tumor necrosis factor receptor superfamily, member 1...    56   6e-08
gi|21361086 tumor necrosis factor receptor superfamily, member 1...    55   1e-07
gi|23510423 tumor necrosis factor receptor superfamily, member 6...    55   1e-07
gi|23510421 tumor necrosis factor receptor superfamily, member 6...    55   1e-07
gi|4507583 tumor necrosis factor receptor superfamily, member 6 ...    55   1e-07
gi|224494019 tumor necrosis factor receptor superfamily, member ...    54   3e-07
gi|224494026 tumor necrosis factor receptor superfamily, member ...    53   5e-07
gi|4507587 tumor necrosis factor receptor superfamily, member 7 ...    50   6e-06
gi|23200023 tumor necrosis factor receptor superfamily, member 2...    49   1e-05
gi|23200021 tumor necrosis factor receptor superfamily, member 2...    49   1e-05
gi|89142745 tumor necrosis factor receptor superfamily, member 2...    49   1e-05
gi|4507569 tumor necrosis factor receptor superfamily, member 25...    49   1e-05
gi|22547108 tumor necrosis factor receptor superfamily, member 1...    49   1e-05
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         48   2e-05
gi|11140823 X-linked ectodysplasin receptor [Homo sapiens]             48   2e-05

>gi|4507577 tumor necrosis factor receptor 2 precursor [Homo
           sapiens]
          Length = 461

 Score =  955 bits (2468), Expect = 0.0
 Identities = 461/461 (100%), Positives = 461/461 (100%)

Query: 1   MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPG 60
           MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPG
Sbjct: 1   MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPG 60

Query: 61  QHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTC 120
           QHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTC
Sbjct: 61  QHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTC 120

Query: 121 RPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICR 180
           RPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICR
Sbjct: 121 RPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICR 180

Query: 181 PHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTS 240
           PHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTS
Sbjct: 181 PHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTS 240

Query: 241 FLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKV 300
           FLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKV
Sbjct: 241 FLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKV 300

Query: 301 PHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGE 360
           PHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGE
Sbjct: 301 PHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGE 360

Query: 361 ARASTGSSDSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQ 420
           ARASTGSSDSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQ
Sbjct: 361 ARASTGSSDSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQ 420

Query: 421 VPFSKEECAFRSQLETPETLLGSTEEKPLPLGVPDAGMKPS 461
           VPFSKEECAFRSQLETPETLLGSTEEKPLPLGVPDAGMKPS
Sbjct: 421 VPFSKEECAFRSQLETPETLLGSTEEKPLPLGVPDAGMKPS 461


>gi|14790170 tumor necrosis factor receptor superfamily, member 6b
           [Homo sapiens]
          Length = 300

 Score =  129 bits (323), Expect = 7e-30
 Identities = 72/210 (34%), Positives = 102/210 (48%), Gaps = 18/210 (8%)

Query: 13  GLELWAAAHALPAQV---AFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTK 69
           GL L     ALPA +   A    A  P    R  E  ++   + C++C PG   +  C +
Sbjct: 8   GLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGER---LVCAQCPPGTFVQRPCRR 64

Query: 70  TSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALS 129
            S T C  C    YTQ WN++  C  C   C   + E +AC    NR C CR G++    
Sbjct: 65  DSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAG 124

Query: 130 KQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVA 189
                  C     C PG GV  PGT + +  C+PC PGTFS ++SS++ C+PH+ C  + 
Sbjct: 125 ------FCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALG 178

Query: 190 ----IPGNASMDAVCTSTS--PTRSMAPGA 213
               +PG++S D +CTS +  P  +  PGA
Sbjct: 179 LALNVPGSSSHDTLCTSCTGFPLSTRVPGA 208


>gi|4507585 tumor necrosis factor receptor superfamily, member 6b
           [Homo sapiens]
          Length = 300

 Score =  129 bits (323), Expect = 7e-30
 Identities = 72/210 (34%), Positives = 102/210 (48%), Gaps = 18/210 (8%)

Query: 13  GLELWAAAHALPAQV---AFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTK 69
           GL L     ALPA +   A    A  P    R  E  ++   + C++C PG   +  C +
Sbjct: 8   GLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGER---LVCAQCPPGTFVQRPCRR 64

Query: 70  TSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALS 129
            S T C  C    YTQ WN++  C  C   C   + E +AC    NR C CR G++    
Sbjct: 65  DSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAG 124

Query: 130 KQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVA 189
                  C     C PG GV  PGT + +  C+PC PGTFS ++SS++ C+PH+ C  + 
Sbjct: 125 ------FCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALG 178

Query: 190 ----IPGNASMDAVCTSTS--PTRSMAPGA 213
               +PG++S D +CTS +  P  +  PGA
Sbjct: 179 LALNVPGSSSHDTLCTSCTGFPLSTRVPGA 208


>gi|148743793 osteoprotegerin precursor [Homo sapiens]
          Length = 401

 Score =  128 bits (321), Expect = 1e-29
 Identities = 66/166 (39%), Positives = 81/166 (48%), Gaps = 12/166 (7%)

Query: 45  YYDQTA--QMCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSS 102
           +YD+    Q+ C KC PG + K  CT    TVC  C D  YT  W+   ECL C   C  
Sbjct: 30  HYDEETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDHYYTDSWHTSDECLYCSPVCKE 89

Query: 103 DQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCK 162
            Q   Q C R  NR+C C+ G Y  +        C   R C PGFGV + GT   + VCK
Sbjct: 90  LQYVKQECNRTHNRVCECKEGRYLEI------EFCLKHRSCPPGFGVVQAGTPERNTVCK 143

Query: 163 PCAPGTFSNTTSSTDICRPHQICNVVAI----PGNASMDAVCTSTS 204
            C  G FSN TSS   CR H  C+V  +     GNA+ D +C+  S
Sbjct: 144 RCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNATHDNICSGNS 189


>gi|7657039 tumor necrosis factor receptor superfamily, member 21
           precursor [Homo sapiens]
          Length = 655

 Score =  120 bits (301), Expect = 3e-27
 Identities = 92/305 (30%), Positives = 131/305 (42%), Gaps = 39/305 (12%)

Query: 52  MCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACT 111
           + C KC  G +    CT TS  VC SC   T+T+  N + +C  C   C    +E   C 
Sbjct: 65  LTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKLPCA 124

Query: 112 REQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSN 171
              +R CTC PG +      +    CAP   C  G+GV + GTET DV CK CA GTFS+
Sbjct: 125 ALTDRECTCPPGMF------QSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSD 178

Query: 172 TTSSTDICRPHQIC---NVVAI-PGNASMDAVC---TSTSPTRSMAPGAVHLPQPVSTRS 224
             SS   C+ +  C   N+V I PG    D VC    S S + S +PG    P+P     
Sbjct: 179 VPSSVMKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSSTSPSPGTAIFPRP----- 233

Query: 225 QHTQPTPEPSTAPSTSFLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIM 284
           +H +    PS     S  +P G +     S+          V    L  +  G V     
Sbjct: 234 EHMETHEVPS-----STYVPKGMNSTESNSSAS--------VRPKVLSSIQEGTVPDNTS 280

Query: 285 TQVKKKPLCLQREAKVPHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPT 344
           +   K+ +       +P+L        QGP  +H+L   PS  ++  E S++ +  + P 
Sbjct: 281 SARGKEDV----NKTLPNLQV--VNHQQGPHHRHILKLLPSMEATGGEKSSTPI--KGPK 332

Query: 345 RNQPQ 349
           R  P+
Sbjct: 333 RGHPR 337


>gi|4505039 lymphotoxin beta receptor [Homo sapiens]
          Length = 435

 Score =  117 bits (293), Expect = 2e-26
 Identities = 76/215 (35%), Positives = 99/215 (46%), Gaps = 29/215 (13%)

Query: 2   APVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCR--LREYYDQTAQMCCSKCSP 59
           AP   W  L +GL    AA       A  PYA E   TCR   +EYY+   ++CCS+C P
Sbjct: 9   APGLAWGPLVLGLFGLLAASQ---PQAVPPYASE-NQTCRDQEKEYYEPQHRICCSRCPP 64

Query: 60  GQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQV----ETQACTREQN 115
           G +    C++  DTVC +C +++Y + WN++  C  C      D V    E   CT ++ 
Sbjct: 65  GTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCR---PCDPVMGLEEIAPCTSKRK 121

Query: 116 RICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVV------CKPCAPGTF 169
             C C+PG +CA    E C  C  L  C PG        E  D V      C PC  G F
Sbjct: 122 TQCRCQPGMFCAAWALE-CTHCELLSDCPPG-----TEAELKDEVGKGNNHCVPCKAGHF 175

Query: 170 SNTTSSTDICRPHQICN----VVAIPGNASMDAVC 200
            NT+S +  C+PH  C     V A PG A  D  C
Sbjct: 176 QNTSSPSARCQPHTRCENQGLVEAAPGTAQSDTTC 210


>gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]
          Length = 277

 Score =  114 bits (286), Expect = 1e-25
 Identities = 66/187 (35%), Positives = 88/187 (47%), Gaps = 14/187 (7%)

Query: 30  TPYAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNW 89
           T   PEP + CR ++Y   +   CCS C PGQ     CT+ ++T C  C +S +   WN 
Sbjct: 16  TAVHPEPPTACREKQYLINS--QCCSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNR 73

Query: 90  VPECLSCGSRCSSD---QVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPG 146
              C      C  +   +V+ Q  T E + ICTC  GW+C     E C  C   R C PG
Sbjct: 74  ETHCHQ-HKYCDPNLGLRVQ-QKGTSETDTICTCEEGWHCT---SEACESCVLHRSCSPG 128

Query: 147 FGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICN----VVAIPGNASMDAVCTS 202
           FGV +  T  SD +C+PC  G FSN +S+ + C P   C     VV   G    D VC  
Sbjct: 129 FGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHPWTSCETKDLVVQQAGTNKTDVVCGP 188

Query: 203 TSPTRSM 209
               R++
Sbjct: 189 QDRLRAL 195


>gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]
          Length = 203

 Score =  108 bits (271), Expect = 8e-24
 Identities = 58/155 (37%), Positives = 78/155 (50%), Gaps = 10/155 (6%)

Query: 30  TPYAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNW 89
           T   PEP + CR ++Y   +   CCS C PGQ     CT+ ++T C  C +S +   WN 
Sbjct: 16  TAVHPEPPTACREKQYLINS--QCCSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNR 73

Query: 90  VPECLSCGSRCSSD---QVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPG 146
              C      C  +   +V+ Q  T E + ICTC  GW+C     E C  C   R C PG
Sbjct: 74  ETHCHQ-HKYCDPNLGLRVQ-QKGTSETDTICTCEEGWHCT---SEACESCVLHRSCSPG 128

Query: 147 FGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRP 181
           FGV +  T  SD +C+PC  G FSN +S+ + C P
Sbjct: 129 FGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHP 163



 Score = 36.6 bits (83), Expect = 0.049
 Identities = 18/64 (28%), Positives = 28/64 (43%), Gaps = 5/64 (7%)

Query: 143 CRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNV-----VAIPGNASMD 197
           C+PG  +    TE ++  C PC    F +T +    C  H+ C+      V   G +  D
Sbjct: 41  CQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCDPNLGLRVQQKGTSETD 100

Query: 198 AVCT 201
            +CT
Sbjct: 101 TICT 104


>gi|4507565 tumor necrosis factor receptor superfamily, member 11a
           precursor [Homo sapiens]
          Length = 616

 Score =  105 bits (263), Expect = 7e-23
 Identities = 64/186 (34%), Positives = 84/186 (45%), Gaps = 13/186 (6%)

Query: 40  CRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSR 99
           C   ++Y+   + CC+KC PG++    CT TSD+VC  C    Y   WN   +CL     
Sbjct: 34  CTSEKHYEHLGR-CCNKCEPGKYMSSKCTTTSDSVCLPCGPDEYLDSWNEEDKCL-LHKV 91

Query: 100 CSSDQ--VETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETS 157
           C + +  V   A      R C C  G++ +    + C  C    +C PG G   P     
Sbjct: 92  CDTGKALVAVVAGNSTTPRRCACTAGYHWS----QDCECCRRNTECAPGLGAQHPLQLNK 147

Query: 158 DVVCKPCAPGTFSNTTSSTDICRPHQICNV----VAIPGNASMDAVCTSTSPTRSMAPGA 213
           D VCKPC  G FS+  SSTD CRP   C      V   G    DAVC+S+ P R   P  
Sbjct: 148 DTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGKRVEHHGTEKSDAVCSSSLPARK-PPNE 206

Query: 214 VHLPQP 219
            H+  P
Sbjct: 207 PHVYLP 212


>gi|23200041 tumor necrosis factor receptor superfamily, member 14
           precursor [Homo sapiens]
          Length = 283

 Score = 98.6 bits (244), Expect = 1e-20
 Identities = 53/146 (36%), Positives = 70/146 (47%), Gaps = 16/146 (10%)

Query: 32  YAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVP 91
           YAP   S C+  EY       CC KCSPG   K  C + + TVC+ C   TY    N + 
Sbjct: 35  YAPALPS-CKEDEY--PVGSECCPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLS 91

Query: 92  ECLSC-------GSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCR 144
           +CL C       G R S +      C+R +N +C C PG +C +   + C  C       
Sbjct: 92  KCLQCQMCDPAMGLRASRN------CSRTENAVCGCSPGHFCIVQDGDHCAACRAYATSS 145

Query: 145 PGFGVARPGTETSDVVCKPCAPGTFS 170
           PG  V + GTE+ D +C+ C PGTFS
Sbjct: 146 PGQRVQKGGTESQDTLCQNCPPGTFS 171



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 2/50 (4%)

Query: 137 CAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICN 186
           C P  KC PG+ V     E +  VC+PC PGT+    +    C   Q+C+
Sbjct: 53  CCP--KCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCD 100


>gi|68348711 tumor necrosis factor receptor superfamily, member 8
           isoform 1 precursor [Homo sapiens]
          Length = 595

 Score = 88.6 bits (218), Expect = 1e-17
 Identities = 67/246 (27%), Positives = 88/246 (35%), Gaps = 17/246 (6%)

Query: 11  AVGLELWAAAHALPAQVAFTPYAPEPGSTCRLR--EYYDQTAQMCCSKCSPGQHAKVFCT 68
           A+GL    A  A P    F         TC      YYD+  + CC +C  G      C 
Sbjct: 7   ALGLLFLGALRAFPQDRPFE-------DTCHGNPSHYYDKAVRRCCYRCPMGLFPTQQCP 59

Query: 69  KTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCAL 128
           +        CE   Y    +    C++C      D VE   C    +R+C CRPG +C+ 
Sbjct: 60  QRPTDCRKQCEPDYYLDEADRCTACVTCSR---DDLVEKTPCAWNSSRVCECRPGMFCST 116

Query: 129 SKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVV 188
           S    C  C     C  G  V  PGT   + VC+P +PG      S  +   P       
Sbjct: 117 SAVNSCARCFFHSVCPAGMIVKFPGTAQKNTVCEPASPGVSPACASPENCKEPSSGTIPQ 176

Query: 189 AIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTS-FLLPMGP 247
           A P   S      ST P R    G   L Q  +++      +P     PS+   L P  P
Sbjct: 177 AKPTPVSPATSSASTMPVR----GGTRLAQEAASKLTRAPDSPSSVGRPSSDPGLSPTQP 232

Query: 248 SPPAEG 253
            P   G
Sbjct: 233 CPEGSG 238



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 81/320 (25%), Positives = 112/320 (35%), Gaps = 56/320 (17%)

Query: 59  PGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRIC 118
           PG      C + S      CE   Y         C+SC      D VE   C    +R C
Sbjct: 225 PGLSPTQPCPEGSGDCRKQCEPDYYLDEAGRCTACVSCSR---DDLVEKTPCAWNSSRTC 281

Query: 119 TCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDI 178
            CRPG  CA S       C P   C      A   T+  D+  K        +TT     
Sbjct: 282 ECRPGMICATSATNSRARCVPYPIC-----AAETVTKPQDMAEK--------DTTFEAPP 328

Query: 179 CRPHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPS 238
                 CN     G A       STSPT+S+              SQ ++  P P++A  
Sbjct: 329 LGTQPDCNPTPENGEAP-----ASTSPTQSLL-----------VDSQASKTLPIPTSA-- 370

Query: 239 TSFLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREA 298
                     P A  STG   L  G ++    L L+++   +  ++     +  C +R  
Sbjct: 371 ----------PVALSSTGKPVLDAGPVLFWVILVLVVVVGSSAFLLCH---RRACRKRIR 417

Query: 299 KVPHL--PADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEA- 355
           +  HL  P      T  P+ + L+ + P  SS+ L S AS  +  A  R     P +E  
Sbjct: 418 QKLHLCYPVQ----TSQPKLE-LVDSRPRRSSTQLRSGASVTEPVAEERGLMSQPLMETC 472

Query: 356 -SGAGEARASTGSSDSSPGG 374
            S       S    D+SP G
Sbjct: 473 HSVGAAYLESLPLQDASPAG 492


>gi|4507579 tumor necrosis factor receptor superfamily, member 4
           precursor [Homo sapiens]
          Length = 277

 Score = 73.2 bits (178), Expect = 5e-13
 Identities = 64/230 (27%), Positives = 86/230 (37%), Gaps = 44/230 (19%)

Query: 53  CCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVP--ECLSCGSRCSSDQVETQAC 110
           CC +C PG      C+++ +TVC  C    Y  + +  P   C  C  R  S++   Q C
Sbjct: 42  CCHECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGSER--KQLC 99

Query: 111 TREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFS 170
           T  Q+ +C CR G               PL   +PG            V C PC PG FS
Sbjct: 100 TATQDTVCRCRAG-------------TQPLDSYKPG------------VDCAPCPPGHFS 134

Query: 171 NTTSSTDICRPHQICNVVA----IPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQH 226
                   C+P   C +       P + S DA+C    P  +  P     P       Q 
Sbjct: 135 --PGDNQACKPWTNCTLAGKHTLQPASNSSDAICEDRDPPATQ-PQETQGPPARPITVQP 191

Query: 227 TQPTPEPSTAPSTSFLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLII 276
           T+  P  S  PST       P     G      L +GL++G+  LG L I
Sbjct: 192 TEAWPRTSQGPSTR------PVEVPGGRAVAAILGLGLVLGL--LGPLAI 233


>gi|4505393 nerve growth factor receptor precursor [Homo sapiens]
          Length = 427

 Score = 69.7 bits (169), Expect = 5e-12
 Identities = 52/188 (27%), Positives = 75/188 (39%), Gaps = 19/188 (10%)

Query: 53  CCSKCSPGQHAKVFCTKTSDTVCDSCEDS-TYTQLWNWVPECLSCGSRCSSDQVETQACT 111
           CC  C+ G+     C   + TVC+ C DS T++ + +    C  C + C   Q  +  C 
Sbjct: 43  CCKACNLGEGVAQPCG-ANQTVCEPCLDSVTFSDVVSATEPCKPC-TECVGLQSMSAPCV 100

Query: 112 REQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSN 171
              + +C C  G+Y    + E    C   R C  G G+     +  + VC+ C  GT+S+
Sbjct: 101 EADDAVCRCAYGYY----QDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSD 156

Query: 172 TTSSTDICRPHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTP 231
             +  D C P  +C           D        TR        +P    TRS  T P  
Sbjct: 157 EANHVDPCLPCTVCE----------DTERQLRECTRWADAECEEIPGRWITRS--TPPEG 204

Query: 232 EPSTAPST 239
             STAPST
Sbjct: 205 SDSTAPST 212



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 33/103 (32%), Positives = 43/103 (41%), Gaps = 4/103 (3%)

Query: 40  CRLREYYDQTAQMC--CSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCG 97
           C    Y D+T   C  C  C  G      C    +TVC+ C D TY+   N V  CL C 
Sbjct: 109 CAYGYYQDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPC- 167

Query: 98  SRCSSDQVETQACTREQNRICTCRPG-WYCALSKQEGCRLCAP 139
           + C   + + + CTR  +  C   PG W    +  EG    AP
Sbjct: 168 TVCEDTERQLRECTRWADAECEEIPGRWITRSTPPEGSDSTAP 210


>gi|5730095 tumor necrosis factor receptor superfamily, member 9
           precursor [Homo sapiens]
          Length = 255

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 48/180 (26%), Positives = 72/180 (40%), Gaps = 26/180 (14%)

Query: 54  CSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTRE 113
           CS C  G     FC    + +C  C  ++++        C  C  +C       + C+  
Sbjct: 28  CSNCPAG----TFCDNNRNQICSPCPPNSFSSAGGQ-RTCDIC-RQCKGVFRTRKECSST 81

Query: 114 QNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTT 173
            N  C C PG++C      GC +C   + C+ G  + + G       CK C  GTF++  
Sbjct: 82  SNAECDCTPGFHCL---GAGCSMCE--QDCKQGQELTKKG-------CKDCCFGTFND-- 127

Query: 174 SSTDICRPHQICNV----VAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQP 229
               ICRP   C++    V + G    D VC   SP   ++PGA  +  P   R     P
Sbjct: 128 QKRGICRPWTNCSLDGKSVLVNGTKERDVVC-GPSPA-DLSPGASSVTPPAPAREPGHSP 185


>gi|4507575 tumor necrosis factor receptor 1 precursor [Homo
           sapiens]
          Length = 455

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 48/165 (29%), Positives = 68/165 (41%), Gaps = 20/165 (12%)

Query: 38  STCRLREY-YDQTAQMCCSKCSPGQHAKVFCT-KTSDTVCDSCEDSTYTQLWNWVPECLS 95
           S C   +Y + Q   +CC+KC  G +    C     DT C  CE  ++T   N +  CLS
Sbjct: 42  SVCPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLS 101

Query: 96  CGSRCSSD--QVETQACTREQNRICTCRPG-----WYCALSKQEGCRLCAPLRKCRPGFG 148
           C S+C  +  QVE  +CT +++ +C CR       W   L +   C LC           
Sbjct: 102 C-SKCRKEMGQVEISSCTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCL-------NGT 153

Query: 149 VARPGTETSDVVCKPCAPGTF--SNTTSSTDICRPHQICNVVAIP 191
           V     E  + VC  C  G F   N   S   C+    C  + +P
Sbjct: 154 VHLSCQEKQNTVC-TCHAGFFLRENECVSCSNCKKSLECTKLCLP 197



 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 38/122 (31%), Positives = 54/122 (44%), Gaps = 15/122 (12%)

Query: 34  PEPG--STCRLREYYDQTAQ-------MCCSKCSP--GQHAKVFCTKTSDTVCDSCEDST 82
           P PG  + CR  E    TA        + CSKC    GQ     CT   DTVC  C  + 
Sbjct: 73  PGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTVC-GCRKNQ 131

Query: 83  YTQLWNW-VPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLR 141
           Y   W+  + +C +C S C +  V   +C  +QN +CTC  G++   ++   C  C    
Sbjct: 132 YRHYWSENLFQCFNC-SLCLNGTVHL-SCQEKQNTVCTCHAGFFLRENECVSCSNCKKSL 189

Query: 142 KC 143
           +C
Sbjct: 190 EC 191


>gi|22547121 tumor necrosis factor receptor superfamily, member 10c
           precursor [Homo sapiens]
          Length = 259

 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 52/212 (24%), Positives = 80/212 (37%), Gaps = 25/212 (11%)

Query: 75  CDSCEDST-YTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEG 133
           C+ C +   YT   N  P C  C + C SDQ    +CT  ++ +C C+ G +   +  E 
Sbjct: 66  CNPCTEGVDYTNASNNEPSCFPC-TVCKSDQKHKSSCTMTRDTVCQCKEGTFRNENSPEM 124

Query: 134 CRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVAIPGN 193
           CR C+   +C  G       T   D+    C     +N T  T                N
Sbjct: 125 CRKCS---RCPSGEVQVSNCTSWDDI---QCVEEFGANATVETPAAEETM---------N 169

Query: 194 ASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQP-TPEPSTAPSTSFLLPMGPSPPAE 252
            S      +   T + +PG    P P +  +  T P TP P+ A  T    P  P+P AE
Sbjct: 170 TSPGTPAPAAEETMNTSPGT---PAPAAEETMTTSPGTPAPA-AEETMTTSPGTPAPAAE 225

Query: 253 GSTGDFALPVGLIVGVTALGLLIIGVVNCVIM 284
            +        G       L   I+G++  +++
Sbjct: 226 ET---MTTSPGTPASSHYLSCTIVGIIVLIVL 254



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 23/58 (39%), Positives = 29/58 (50%), Gaps = 3/58 (5%)

Query: 54  CSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACT 111
           C+ C   Q  K  CT T DTVC  C++ T+    N    C  C SRC S +V+   CT
Sbjct: 88  CTVCKSDQKHKSSCTMTRDTVC-QCKEGTFRN-ENSPEMCRKC-SRCPSGEVQVSNCT 142


>gi|21361086 tumor necrosis factor receptor superfamily, member 10a
           [Homo sapiens]
          Length = 468

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 34/106 (32%), Positives = 46/106 (43%), Gaps = 9/106 (8%)

Query: 57  CSPGQHAKVFCTKTSDTVCDSCEDST-YTQLWNWVPECLSCGSRCSSDQVETQACTREQN 115
           C PG H            C+ C +   YT   N +  CL C + C SD+ E   CT  +N
Sbjct: 132 CPPGSHRS-----EHPGACNRCTEGVGYTNASNNLFACLPC-TACKSDEEERSPCTTTRN 185

Query: 116 RICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVC 161
             C C+PG +   +  E CR C+  R C  G    +  T  SD+ C
Sbjct: 186 TACQCKPGTFRNDNSAEMCRKCS--RGCPRGMVKVKDCTPWSDIEC 229



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 16/58 (27%), Positives = 24/58 (41%), Gaps = 2/58 (3%)

Query: 54  CSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACT 111
           C+ C   +  +  CT T +T C  C+  T+    N    C  C   C    V+ + CT
Sbjct: 167 CTACKSDEEERSPCTTTRNTAC-QCKPGTFRN-DNSAEMCRKCSRGCPRGMVKVKDCT 222


>gi|23510423 tumor necrosis factor receptor superfamily, member 6
           isoform 3 precursor [Homo sapiens]
          Length = 220

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 35/115 (30%), Positives = 49/115 (42%), Gaps = 8/115 (6%)

Query: 51  QMCCSKCSPGQHAKVFCTKTSDTV-CDSCEDST-YTQLWNWVPECLSCGSRCSSDQVETQ 108
           Q C   C PG+     CT   D   C  C++   YT   ++  +C  C        +E +
Sbjct: 57  QFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVE 116

Query: 109 A-CTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCK 162
             CTR QN  C C+P ++C       C  C P  KC    G+ +  T TS+  CK
Sbjct: 117 INCTRTQNTKCRCKPNFFC---NSTVCEHCDPCTKCE--HGIIKECTLTSNTKCK 166


>gi|23510421 tumor necrosis factor receptor superfamily, member 6
           isoform 2 precursor [Homo sapiens]
          Length = 314

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 35/115 (30%), Positives = 49/115 (42%), Gaps = 8/115 (6%)

Query: 51  QMCCSKCSPGQHAKVFCTKTSDTV-CDSCEDST-YTQLWNWVPECLSCGSRCSSDQVETQ 108
           Q C   C PG+     CT   D   C  C++   YT   ++  +C  C        +E +
Sbjct: 57  QFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVE 116

Query: 109 A-CTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCK 162
             CTR QN  C C+P ++C       C  C P  KC    G+ +  T TS+  CK
Sbjct: 117 INCTRTQNTKCRCKPNFFC---NSTVCEHCDPCTKCE--HGIIKECTLTSNTKCK 166


>gi|4507583 tumor necrosis factor receptor superfamily, member 6
           isoform 1 precursor [Homo sapiens]
          Length = 335

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 35/115 (30%), Positives = 49/115 (42%), Gaps = 8/115 (6%)

Query: 51  QMCCSKCSPGQHAKVFCTKTSDTV-CDSCEDST-YTQLWNWVPECLSCGSRCSSDQVETQ 108
           Q C   C PG+     CT   D   C  C++   YT   ++  +C  C        +E +
Sbjct: 57  QFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVE 116

Query: 109 A-CTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCK 162
             CTR QN  C C+P ++C       C  C P  KC    G+ +  T TS+  CK
Sbjct: 117 INCTRTQNTKCRCKPNFFC---NSTVCEHCDPCTKCE--HGIIKECTLTSNTKCK 166


>gi|224494019 tumor necrosis factor receptor superfamily, member 10b
           isoform 1 precursor [Homo sapiens]
          Length = 440

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 39/117 (33%), Positives = 50/117 (42%), Gaps = 17/117 (14%)

Query: 57  CSPGQHAKVFCTKTSDTVCDSCE-DSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQN 115
           C PG H            C SC+    Y+  WN +  CL C +RC S +VE   CT  +N
Sbjct: 81  CPPGHHIS-----EDGRDCISCKYGQDYSTHWNDLLFCLRC-TRCDSGEVELSPCTTTRN 134

Query: 116 RICTCRPGWYCALSKQEGCRLCAPLRKCRPGF--GVARPG--TETSDVVCKPCAPGT 168
            +C C  G +      E C      RKCR G   G+ + G  T  SD+ C     GT
Sbjct: 135 TVCQCEEGTFREEDSPEMC------RKCRTGCPRGMVKVGDCTPWSDIECVHKESGT 185



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 4/59 (6%)

Query: 54  CSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPE-CLSCGSRCSSDQVETQACT 111
           C++C  G+     CT T +TVC  CE+ T+ +     PE C  C + C    V+   CT
Sbjct: 116 CTRCDSGEVELSPCTTTRNTVC-QCEEGTFRE--EDSPEMCRKCRTGCPRGMVKVGDCT 171


>gi|224494026 tumor necrosis factor receptor superfamily, member 10b
           isoform 2 precursor [Homo sapiens]
          Length = 411

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 37/110 (33%), Positives = 48/110 (43%), Gaps = 17/110 (15%)

Query: 57  CSPGQHAKVFCTKTSDTVCDSCE-DSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQN 115
           C PG H            C SC+    Y+  WN +  CL C +RC S +VE   CT  +N
Sbjct: 81  CPPGHHIS-----EDGRDCISCKYGQDYSTHWNDLLFCLRC-TRCDSGEVELSPCTTTRN 134

Query: 116 RICTCRPGWYCALSKQEGCRLCAPLRKCRPGF--GVARPG--TETSDVVC 161
            +C C  G +      E C      RKCR G   G+ + G  T  SD+ C
Sbjct: 135 TVCQCEEGTFREEDSPEMC------RKCRTGCPRGMVKVGDCTPWSDIEC 178



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 4/59 (6%)

Query: 54  CSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPE-CLSCGSRCSSDQVETQACT 111
           C++C  G+     CT T +TVC  CE+ T+ +     PE C  C + C    V+   CT
Sbjct: 116 CTRCDSGEVELSPCTTTRNTVC-QCEEGTFRE--EDSPEMCRKCRTGCPRGMVKVGDCT 171


>gi|4507587 tumor necrosis factor receptor superfamily, member 7
           precursor [Homo sapiens]
          Length = 260

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 35/109 (32%), Positives = 48/109 (44%), Gaps = 9/109 (8%)

Query: 34  PEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTV-CDSCEDS-TYTQLWNWVP 91
           P P S C  R Y+ Q  ++CC  C PG      C +      CD C    +++   +  P
Sbjct: 22  PAPKS-CPERHYWAQ-GKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRP 79

Query: 92  ECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPL 140
            C SC   C+S  +  + CT   N  C CR GW C   + + C  C PL
Sbjct: 80  HCESC-RHCNSGLL-VRNCTITANAECACRNGWQC---RDKECTECDPL 123


>gi|23200023 tumor necrosis factor receptor superfamily, member 25
           isoform 3 precursor [Homo sapiens]
          Length = 380

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 33/137 (24%), Positives = 53/137 (38%), Gaps = 11/137 (8%)

Query: 44  EYYDQTAQMCCSKCSPGQHAKVFCTKT-SDTVCDSCEDSTYTQLWNW----VPECLSCGS 98
           +++ +    CC  C  G + K  CT+   ++ C  C   T+    N        C +C  
Sbjct: 38  DFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDE 97

Query: 99  RCSSDQVETQACTREQNRICTCRPGWY--CALSK--QEGCRLCAPLRKCRPGFGVARPGT 154
           + S  QV  + C+   +  C C+PGW+  C +S+        C P   C       R   
Sbjct: 98  QAS--QVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLC 155

Query: 155 ETSDVVCKPCAPGTFSN 171
              D  C  C PG + +
Sbjct: 156 SRRDTDCGTCLPGFYEH 172


>gi|23200021 tumor necrosis factor receptor superfamily, member 25
           isoform 1 precursor [Homo sapiens]
          Length = 426

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 33/137 (24%), Positives = 53/137 (38%), Gaps = 11/137 (8%)

Query: 44  EYYDQTAQMCCSKCSPGQHAKVFCTKT-SDTVCDSCEDSTYTQLWNW----VPECLSCGS 98
           +++ +    CC  C  G + K  CT+   ++ C  C   T+    N        C +C  
Sbjct: 38  DFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDE 97

Query: 99  RCSSDQVETQACTREQNRICTCRPGWY--CALSK--QEGCRLCAPLRKCRPGFGVARPGT 154
           + S  QV  + C+   +  C C+PGW+  C +S+        C P   C       R   
Sbjct: 98  QAS--QVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLC 155

Query: 155 ETSDVVCKPCAPGTFSN 171
              D  C  C PG + +
Sbjct: 156 SRRDTDCGTCLPGFYEH 172


>gi|89142745 tumor necrosis factor receptor superfamily, member 25
           isoform 12 precursor [Homo sapiens]
          Length = 181

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 33/137 (24%), Positives = 53/137 (38%), Gaps = 11/137 (8%)

Query: 44  EYYDQTAQMCCSKCSPGQHAKVFCTKT-SDTVCDSCEDSTYTQLWNW----VPECLSCGS 98
           +++ +    CC  C  G + K  CT+   ++ C  C   T+    N        C +C  
Sbjct: 38  DFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDE 97

Query: 99  RCSSDQVETQACTREQNRICTCRPGWY--CALSK--QEGCRLCAPLRKCRPGFGVARPGT 154
           + S  QV  + C+   +  C C+PGW+  C +S+        C P   C       R   
Sbjct: 98  QAS--QVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLC 155

Query: 155 ETSDVVCKPCAPGTFSN 171
              D  C  C PG + +
Sbjct: 156 SRRDTDCGTCLPGFYEH 172


>gi|4507569 tumor necrosis factor receptor superfamily, member 25
           isoform 2 precursor [Homo sapiens]
          Length = 417

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 33/137 (24%), Positives = 53/137 (38%), Gaps = 11/137 (8%)

Query: 44  EYYDQTAQMCCSKCSPGQHAKVFCTKT-SDTVCDSCEDSTYTQLWNW----VPECLSCGS 98
           +++ +    CC  C  G + K  CT+   ++ C  C   T+    N        C +C  
Sbjct: 38  DFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDE 97

Query: 99  RCSSDQVETQACTREQNRICTCRPGWY--CALSK--QEGCRLCAPLRKCRPGFGVARPGT 154
           + S  QV  + C+   +  C C+PGW+  C +S+        C P   C       R   
Sbjct: 98  QAS--QVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLC 155

Query: 155 ETSDVVCKPCAPGTFSN 171
              D  C  C PG + +
Sbjct: 156 SRRDTDCGTCLPGFYEH 172


>gi|22547108 tumor necrosis factor receptor superfamily, member 10d
           precursor [Homo sapiens]
          Length = 386

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 31/108 (28%), Positives = 44/108 (40%), Gaps = 9/108 (8%)

Query: 56  KCSPGQHAKVFCTKTSDTVCDSCEDST-YTQLWNWVPECLSCGSRCSSDQVETQACTREQ 114
           +C  G H   +        C+ C +   YT   N +P CL C + C S Q    +CT  +
Sbjct: 82  ECPAGSHRSEYTG-----ACNPCTEGVDYTIASNNLPSCLLC-TVCKSGQTNKSSCTTTR 135

Query: 115 NRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCK 162
           + +C C  G +   +  E CR C     C  G       T  SD+ CK
Sbjct: 136 DTVCQCEKGSFQDKNSPEMCRTCR--TGCPRGMVKVSNCTPRSDIKCK 181



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 23/67 (34%), Positives = 31/67 (46%), Gaps = 2/67 (2%)

Query: 52  MCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACT 111
           + C+ C  GQ  K  CT T DTVC  CE  ++ Q  N    C +C + C    V+   CT
Sbjct: 116 LLCTVCKSGQTNKSSCTTTRDTVC-QCEKGSF-QDKNSPEMCRTCRTGCPRGMVKVSNCT 173

Query: 112 REQNRIC 118
              +  C
Sbjct: 174 PRSDIKC 180


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 38/151 (25%), Positives = 58/151 (38%)

Query: 306  DKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGEARAST 365
            DKA+  Q   ++    ++ SS SSS  SS+S+         +    G    G G    S 
Sbjct: 2545 DKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSA 2604

Query: 366  GSSDSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQVPFSK 425
             SS ++     +  + +   +  SSS  SS  SS +SS+   + SS S S        S 
Sbjct: 2605 ASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2664

Query: 426  EECAFRSQLETPETLLGSTEEKPLPLGVPDA 456
               +  S  +   +     E  P P   P A
Sbjct: 2665 SSSSSSSTTDEDSSCSSDDEAAPAPTAGPSA 2695



 Score = 37.7 bits (86), Expect = 0.022
 Identities = 34/117 (29%), Positives = 51/117 (43%), Gaps = 23/117 (19%)

Query: 323  APSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGEARASTGSSDSSPGGHGTQVNVT 382
            +P+SSSSS  SS+S+      + +   +    +S +  + +S+ SS SS           
Sbjct: 2611 SPASSSSSSSSSSSS------SSSSSSSSSSSSSSSSSSSSSSSSSSSS----------- 2653

Query: 383  CIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQVPFSKEECAFRSQLETPET 439
                  SSS  SS  SS +SS+   TD   S S  DE  P      + ++ L T  T
Sbjct: 2654 ------SSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKAT 2704



 Score = 30.0 bits (66), Expect = 4.6
 Identities = 56/245 (22%), Positives = 89/245 (36%), Gaps = 40/245 (16%)

Query: 192  GNASMDAVCTSTSPTRSMAPGAVHLP-QPVSTRSQHTQPTP---EPSTAPSTSFLLPMGP 247
            GN + +   T  +   S  PG+   P +PV  R++  +  P   +PS AP      P  P
Sbjct: 2351 GNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCP-AP 2409

Query: 248  SPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKVPHLPADK 307
             P AE      +L    ++ + A               + KK     +  AK P  P ++
Sbjct: 2410 EPFAELPAPATSLAPAPLITMPAT------------RPKPKKARAAEESGAKGPRRPGEE 2457

Query: 308  AR--------GTQGPEQQH-----LLITAPSSSSSSLESSASALDRRAPTR--NQPQAPG 352
            A         G   P+ +      LL   P +       S  +L    P    ++P+AP 
Sbjct: 2458 AELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPW 2517

Query: 353  VEAS--------GAGEARASTGSSDSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASST 404
             +A+        G G     +G+  S       Q       +  SSS  SS  SS +SS+
Sbjct: 2518 PKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSS 2577

Query: 405  MGDTD 409
              +T+
Sbjct: 2578 GSETE 2582


>gi|11140823 X-linked ectodysplasin receptor [Homo sapiens]
          Length = 297

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 38/131 (29%), Positives = 52/131 (39%), Gaps = 24/131 (18%)

Query: 40  CRLREYYDQTAQ-MCCSKCSPGQHAKVFCT--KTSDTVCDSCEDSTYTQLWNWVPECLSC 96
           C+  EY+DQ  + + C +C PGQ     C   +  D  C +C    Y   W     C SC
Sbjct: 3   CQENEYWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGH-HRCQSC 61

Query: 97  GSRCSSDQVETQACTREQNRIC-TCRPGWY-----CALSKQEGCRLCAPLRKCRPGFGVA 150
            +    ++V+   CT   N +C  C P +Y       L  QE    C P  K  P     
Sbjct: 62  ITCAVINRVQKVNCTATSNAVCGDCLPRFYRKTRIGGLQDQE----CIPCTKQTP----- 112

Query: 151 RPGTETSDVVC 161
                TS+V C
Sbjct: 113 -----TSEVQC 118


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.127    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,696,913
Number of Sequences: 37866
Number of extensions: 1268429
Number of successful extensions: 7929
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 75
Number of HSP's successfully gapped in prelim test: 339
Number of HSP's that attempted gapping in prelim test: 6548
Number of HSP's gapped (non-prelim): 1514
length of query: 461
length of database: 18,247,518
effective HSP length: 106
effective length of query: 355
effective length of database: 14,233,722
effective search space: 5052971310
effective search space used: 5052971310
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press