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Search of human proteins with 4507575
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507575 tumor necrosis factor receptor 1 precursor [Homo
sapiens]
(455 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapi... 962 0.0
gi|23200021 tumor necrosis factor receptor superfamily, member 2... 130 2e-30
gi|4507569 tumor necrosis factor receptor superfamily, member 25... 127 2e-29
gi|23200023 tumor necrosis factor receptor superfamily, member 2... 104 2e-22
gi|23200025 tumor necrosis factor receptor superfamily, member 2... 96 9e-20
gi|4505039 lymphotoxin beta receptor [Homo sapiens] 80 4e-15
gi|89142745 tumor necrosis factor receptor superfamily, member 2... 77 4e-14
gi|4505393 nerve growth factor receptor precursor [Homo sapiens] 71 2e-12
gi|23200031 tumor necrosis factor receptor superfamily, member 2... 71 2e-12
gi|148743793 osteoprotegerin precursor [Homo sapiens] 60 4e-09
gi|224494019 tumor necrosis factor receptor superfamily, member ... 59 9e-09
gi|4507577 tumor necrosis factor receptor 2 precursor [Homo sapi... 59 1e-08
gi|224494026 tumor necrosis factor receptor superfamily, member ... 55 2e-07
gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens] 54 2e-07
gi|22547121 tumor necrosis factor receptor superfamily, member 1... 54 2e-07
gi|4507587 tumor necrosis factor receptor superfamily, member 7 ... 54 3e-07
gi|22547108 tumor necrosis factor receptor superfamily, member 1... 54 3e-07
gi|23200041 tumor necrosis factor receptor superfamily, member 1... 53 5e-07
gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens] 50 3e-06
gi|4507565 tumor necrosis factor receptor superfamily, member 11... 50 4e-06
gi|23510423 tumor necrosis factor receptor superfamily, member 6... 49 7e-06
gi|4507583 tumor necrosis factor receptor superfamily, member 6 ... 49 1e-05
gi|68348711 tumor necrosis factor receptor superfamily, member 8... 49 1e-05
gi|21361086 tumor necrosis factor receptor superfamily, member 1... 48 2e-05
gi|11140823 X-linked ectodysplasin receptor [Homo sapiens] 48 2e-05
gi|23510421 tumor necrosis factor receptor superfamily, member 6... 48 2e-05
gi|4507579 tumor necrosis factor receptor superfamily, member 4 ... 47 3e-05
gi|148886654 polydom [Homo sapiens] 46 8e-05
gi|14790170 tumor necrosis factor receptor superfamily, member 6... 44 4e-04
gi|4507585 tumor necrosis factor receptor superfamily, member 6b... 44 4e-04
>gi|4507575 tumor necrosis factor receptor 1 precursor [Homo
sapiens]
Length = 455
Score = 962 bits (2487), Expect = 0.0
Identities = 455/455 (100%), Positives = 455/455 (100%)
Query: 1 MGLSTVPDLLLPLVLLELLVGIYPSGVIGLVPHLGDREKRDSVCPQGKYIHPQNNSICCT 60
MGLSTVPDLLLPLVLLELLVGIYPSGVIGLVPHLGDREKRDSVCPQGKYIHPQNNSICCT
Sbjct: 1 MGLSTVPDLLLPLVLLELLVGIYPSGVIGLVPHLGDREKRDSVCPQGKYIHPQNNSICCT 60
Query: 61 KCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISSCTVD 120
KCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISSCTVD
Sbjct: 61 KCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISSCTVD 120
Query: 121 RDTVCGCRKNQYRHYWSENLFQCFNCSLCLNGTVHLSCQEKQNTVCTCHAGFFLRENECV 180
RDTVCGCRKNQYRHYWSENLFQCFNCSLCLNGTVHLSCQEKQNTVCTCHAGFFLRENECV
Sbjct: 121 RDTVCGCRKNQYRHYWSENLFQCFNCSLCLNGTVHLSCQEKQNTVCTCHAGFFLRENECV 180
Query: 181 SCSNCKKSLECTKLCLPQIENVKGTEDSGTTVLLPLVIFFGLCLLSLLFIGLMYRYQRWK 240
SCSNCKKSLECTKLCLPQIENVKGTEDSGTTVLLPLVIFFGLCLLSLLFIGLMYRYQRWK
Sbjct: 181 SCSNCKKSLECTKLCLPQIENVKGTEDSGTTVLLPLVIFFGLCLLSLLFIGLMYRYQRWK 240
Query: 241 SKLYSIVCGKSTPEKEGELEGTTTKPLAPNPSFSPTPGFTPTLGFSPVPSSTFTSSSTYT 300
SKLYSIVCGKSTPEKEGELEGTTTKPLAPNPSFSPTPGFTPTLGFSPVPSSTFTSSSTYT
Sbjct: 241 SKLYSIVCGKSTPEKEGELEGTTTKPLAPNPSFSPTPGFTPTLGFSPVPSSTFTSSSTYT 300
Query: 301 PGDCPNFAAPRREVAPPYQGADPILATALASDPIPNPLQKWEDSAHKPQSLDTDDPATLY 360
PGDCPNFAAPRREVAPPYQGADPILATALASDPIPNPLQKWEDSAHKPQSLDTDDPATLY
Sbjct: 301 PGDCPNFAAPRREVAPPYQGADPILATALASDPIPNPLQKWEDSAHKPQSLDTDDPATLY 360
Query: 361 AVVENVPPLRWKEFVRRLGLSDHEIDRLELQNGRCLREAQYSMLATWRRRTPRREATLEL 420
AVVENVPPLRWKEFVRRLGLSDHEIDRLELQNGRCLREAQYSMLATWRRRTPRREATLEL
Sbjct: 361 AVVENVPPLRWKEFVRRLGLSDHEIDRLELQNGRCLREAQYSMLATWRRRTPRREATLEL 420
Query: 421 LGRVLRDMDLLGCLEDIEEALCGPAALPPAPSLLR 455
LGRVLRDMDLLGCLEDIEEALCGPAALPPAPSLLR
Sbjct: 421 LGRVLRDMDLLGCLEDIEEALCGPAALPPAPSLLR 455
>gi|23200021 tumor necrosis factor receptor superfamily, member 25
isoform 1 precursor [Homo sapiens]
Length = 426
Score = 130 bits (328), Expect = 2e-30
Identities = 117/411 (28%), Positives = 157/411 (38%), Gaps = 26/411 (6%)
Query: 40 RDSVCPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLR-H 98
R C H + CC C G YL C P ++ C C +F A ENH
Sbjct: 29 RSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSE 88
Query: 99 CLSCSKCRKEMGQVEISSCTVDRDTVCGCRKN-----QYRHYWSENLFQCFNCSLC--LN 151
C C C ++ QV + +C+ DT CGC+ Q S + F C C C L+
Sbjct: 89 CARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALH 148
Query: 152 GTVHLSCQEKQNTVCTCHAGFFLRENECVSCSNCKKSLECTKLCLPQIENVKGTEDSGTT 211
L C + TC GF+ + CVSC SL Q
Sbjct: 149 RHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTPPPSLAGAPWGAVQSAVPLSVAGGRVG 208
Query: 212 VLLPLVIFFGLCLLSLLFIGLMYRYQRWKSKLYSIVCGKSTPEKEGELEGTTTKPLAPNP 271
V V+ GL + LL L Y Y+ C P + G P
Sbjct: 209 VFWVQVLLAGLVVPLLLGATLTYTYRH---------CWPHKPLVTADEAGMEALTPPPAT 259
Query: 272 SFSPTPGFTPTLGFSPVPSSTFTSSSTYTPGDCPNFAAPRREVAPPYQGA-DPILATALA 330
SP TL P S + P + + + P + D + + AL
Sbjct: 260 HLSPLDS-AHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSWDQLPSRALG 318
Query: 331 SDPIPNPLQKWEDSAHKPQSLDTDDPATLYAVVENVPPLRWKEFVRRLGLSDHEIDRLEL 390
P P E A P + P LY V++ VP RWKEFVR LGL + EI+ +E+
Sbjct: 319 --PAAAPTLSPESPAGSPAMMLQPGPQ-LYDVMDAVPARRWKEFVRTLGLREAEIEAVEV 375
Query: 391 QNGRCLREAQYSMLATWRRRTPRREATLELLGRVLRDMDLLGCLEDIEEAL 441
+ GR R+ QY ML WR++ P A L + L M L GC+ED+ L
Sbjct: 376 EIGR-FRDQQYEMLKRWRQQQP---AGLGAVYAALERMGLDGCVEDLRSRL 422
>gi|4507569 tumor necrosis factor receptor superfamily, member 25
isoform 2 precursor [Homo sapiens]
Length = 417
Score = 127 bits (319), Expect = 2e-29
Identities = 117/411 (28%), Positives = 159/411 (38%), Gaps = 35/411 (8%)
Query: 40 RDSVCPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLR-H 98
R C H + CC C G YL C P ++ C C +F A ENH
Sbjct: 29 RSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSE 88
Query: 99 CLSCSKCRKEMGQVEISSCTVDRDTVCGCRKN-----QYRHYWSENLFQCFNCSLC--LN 151
C C C ++ QV + +C+ DT CGC+ Q S + F C C C L+
Sbjct: 89 CARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALH 148
Query: 152 GTVHLSCQEKQNTVCTCHAGFFLRENECVSCSNCKKSLECTKLCLPQIENVKGTEDSGTT 211
L C + TC GF+ + CVSC C + C V G
Sbjct: 149 RHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTSTLG-SCPERCAA----VCGWRQ---- 199
Query: 212 VLLPLVIFFGLCLLSLLFIGLMYRYQRWKSKLYSIVCGKSTPEKEGELEGTTTKPLAPNP 271
+ V+ GL + LL L Y Y+ C P + G P
Sbjct: 200 MFWVQVLLAGLVVPLLLGATLTYTYRH---------CWPHKPLVTADEAGMEALTPPPAT 250
Query: 272 SFSPTPGFTPTLGFSPVPSSTFTSSSTYTPGDCPNFAAPRREVAPPYQGA-DPILATALA 330
SP TL P S + P + + + P + D + + AL
Sbjct: 251 HLSPLDS-AHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSWDQLPSRALG 309
Query: 331 SDPIPNPLQKWEDSAHKPQSLDTDDPATLYAVVENVPPLRWKEFVRRLGLSDHEIDRLEL 390
P P E A P + P LY V++ VP RWKEFVR LGL + EI+ +E+
Sbjct: 310 --PAAAPTLSPESPAGSPAMMLQPGPQ-LYDVMDAVPARRWKEFVRTLGLREAEIEAVEV 366
Query: 391 QNGRCLREAQYSMLATWRRRTPRREATLELLGRVLRDMDLLGCLEDIEEAL 441
+ GR R+ QY ML WR++ P A L + L M L GC+ED+ L
Sbjct: 367 EIGR-FRDQQYEMLKRWRQQQP---AGLGAVYAALERMGLDGCVEDLRSRL 413
>gi|23200023 tumor necrosis factor receptor superfamily, member 25
isoform 3 precursor [Homo sapiens]
Length = 380
Score = 104 bits (259), Expect = 2e-22
Identities = 112/410 (27%), Positives = 156/410 (38%), Gaps = 70/410 (17%)
Query: 40 RDSVCPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLR-H 98
R C H + CC C G YL C P ++ C C +F A ENH
Sbjct: 29 RSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSE 88
Query: 99 CLSCSKCRKEMGQVEISSCTVDRDTVCGCRKN-----QYRHYWSENLFQCFNCSLCLNGT 153
C C C ++ QV + +C+ DT CGC+ Q S + F C C C G
Sbjct: 89 CARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDC--GA 146
Query: 154 VHLSCQEKQNTVCTCHAGFFLRENECVSCSNCKKSLECTKLCLPQI-ENVKGTEDSGTTV 212
+H ++T C R+ +C +C LP E+ G T+
Sbjct: 147 LH------RHTRLLCSR----RDTDCGTC-------------LPGFYEHGDGCVSCPTST 183
Query: 213 LLPLVIFFGLCLLSLLFIGLMYRYQRWKSKLYSIVCGKSTPEKEGELEGTTTKPLAPNPS 272
L G C + + VCG + E +E T P
Sbjct: 184 L-------GSC-----------------PERCAAVCGWR--QNEAGMEALTPPPAT---H 214
Query: 273 FSPTPGFTPTLGFSPVPSSTFTSSSTYTPGDCPNFAAPRREVAPPYQGA-DPILATALAS 331
SP TL P S + P + + + P + D + + AL
Sbjct: 215 LSPLDS-AHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSWDQLPSRALG- 272
Query: 332 DPIPNPLQKWEDSAHKPQSLDTDDPATLYAVVENVPPLRWKEFVRRLGLSDHEIDRLELQ 391
P P E A P + P LY V++ VP RWKEFVR LGL + EI+ +E++
Sbjct: 273 -PAAAPTLSPESPAGSPAMMLQPGPQ-LYDVMDAVPARRWKEFVRTLGLREAEIEAVEVE 330
Query: 392 NGRCLREAQYSMLATWRRRTPRREATLELLGRVLRDMDLLGCLEDIEEAL 441
GR R+ QY ML WR++ P A L + L M L GC+ED+ L
Sbjct: 331 IGR-FRDQQYEMLKRWRQQQP---AGLGAVYAALERMGLDGCVEDLRSRL 376
>gi|23200025 tumor necrosis factor receptor superfamily, member 25
isoform 4 precursor [Homo sapiens]
Length = 372
Score = 95.5 bits (236), Expect = 9e-20
Identities = 100/359 (27%), Positives = 139/359 (38%), Gaps = 34/359 (9%)
Query: 91 ASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTVCGCRKN-----QYRHYWSENLFQCFN 145
A + H + L C + QV + +C+ DT CGC+ Q S + F C
Sbjct: 36 AGDFHKKIGLFCCRGCPAASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQP 95
Query: 146 CSLC--LNGTVHLSCQEKQNTVCTCHAGFFLRENECVSCSNCKKSLECTKLCLPQIENVK 203
C C L+ L C + TC GF+ + CVSC C + C V
Sbjct: 96 CLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTSTLG-SCPERCAA----VC 150
Query: 204 GTEDSGTTVLLPLVIFFGLCLLSLLFIGLMYRYQRWKSKLYSIVCGKSTPEKEGELEGTT 263
G + V+ GL + LL L Y Y+ C P + G
Sbjct: 151 GWRQ----MFWVQVLLAGLVVPLLLGATLTYTYRH---------CWPHKPLVTADEAGME 197
Query: 264 TKPLAPNPSFSPTPGFTPTLGFSPVPSSTFTSSSTYTPGDCPNFAAPRREVAPPYQGA-D 322
P SP TL P S + P + + + P + D
Sbjct: 198 ALTPPPATHLSPLDS-AHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSWD 256
Query: 323 PILATALASDPIPNPLQKWEDSAHKPQSLDTDDPATLYAVVENVPPLRWKEFVRRLGLSD 382
+ + AL P P E A P + P LY V++ VP RWKEFVR LGL +
Sbjct: 257 QLPSRALG--PAAAPTLSPESPAGSPAMMLQPGPQ-LYDVMDAVPARRWKEFVRTLGLRE 313
Query: 383 HEIDRLELQNGRCLREAQYSMLATWRRRTPRREATLELLGRVLRDMDLLGCLEDIEEAL 441
EI+ +E++ GR R+ QY ML WR++ P A L + L M L GC+ED+ L
Sbjct: 314 AEIEAVEVEIGR-FRDQQYEMLKRWRQQQP---AGLGAVYAALERMGLDGCVEDLRSRL 368
>gi|4505039 lymphotoxin beta receptor [Homo sapiens]
Length = 435
Score = 80.1 bits (196), Expect = 4e-15
Identities = 81/271 (29%), Positives = 108/271 (39%), Gaps = 41/271 (15%)
Query: 11 LPLVLLELLVGIYPSGVIGLVPHLGDREK-RDSVCPQGKYIHPQNNSICCTKCHKGTYLY 69
L L L LL P V P+ + + RD + +Y PQ+ ICC++C GTY+
Sbjct: 17 LVLGLFGLLAASQPQAV---PPYASENQTCRDQ---EKEYYEPQHR-ICCSRCPPGTYVS 69
Query: 70 NDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTVCGCRK 129
C +DT C C S+ N+L C C C MG EI+ CT R T C C+
Sbjct: 70 AKCSRI-RDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKRKTQCRCQP 128
Query: 130 NQYRHYWSENLFQCFNCSLCLNGTVHLSCQE--KQNTVCT-CHAGFFLRENECVSCSNCK 186
+ W+ C S C GT E K N C C AG F +N + C+
Sbjct: 129 GMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHF--QNTSSPSARCQ 186
Query: 187 KSLECTKLCLPQIENVKGTEDSGTT--------------------VLLPLVIFFGLCLLS 226
C L +E GT S TT VLLPL F LL+
Sbjct: 187 PHTRCENQGL--VEAAPGTAQSDTTCKNPLEPLPPEMSGTMLMLAVLLPLAFFL---LLA 241
Query: 227 LLFIGLMYRYQRWKSKLYSIVCGKSTPEKEG 257
+F + + KL S++ K P+ EG
Sbjct: 242 TVFSCIWKSHPSLCRKLGSLL--KRRPQGEG 270
>gi|89142745 tumor necrosis factor receptor superfamily, member 25
isoform 12 precursor [Homo sapiens]
Length = 181
Score = 76.6 bits (187), Expect = 4e-14
Identities = 46/151 (30%), Positives = 61/151 (40%), Gaps = 8/151 (5%)
Query: 40 RDSVCPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLR-H 98
R C H + CC C G YL C P ++ C C +F A ENH
Sbjct: 29 RSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSE 88
Query: 99 CLSCSKCRKEMGQVEISSCTVDRDTVCGCRKN-----QYRHYWSENLFQCFNCSLC--LN 151
C C C ++ QV + +C+ DT CGC+ Q S + F C C C L+
Sbjct: 89 CARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALH 148
Query: 152 GTVHLSCQEKQNTVCTCHAGFFLRENECVSC 182
L C + TC GF+ + CVSC
Sbjct: 149 RHTRLLCSRRDTDCGTCLPGFYEHGDGCVSC 179
>gi|4505393 nerve growth factor receptor precursor [Homo sapiens]
Length = 427
Score = 70.9 bits (172), Expect = 2e-12
Identities = 61/205 (29%), Positives = 91/205 (44%), Gaps = 36/205 (17%)
Query: 12 PLVLLELLVGIYPSGVIGLVPHLGDREKRDSVCPQGKYIHPQNNSICCTKCHKGTYLYND 71
P +LL LL+G+ G CP G Y H + CC C+ G +
Sbjct: 13 PRLLLLLLLGVSLGGA-------------KEACPTGLYTH---SGECCKACNLGEGVAQP 56
Query: 72 CPGPGQDTDCREC-ESGSFTASENHLRHCLSCSKCRKEMGQVEISS-CTVDRDTVCGCRK 129
C G Q T C C +S +F+ + C C++C +G +S+ C D VC C
Sbjct: 57 C-GANQ-TVCEPCLDSVTFSDVVSATEPCKPCTEC---VGLQSMSAPCVEADDAVCRCA- 110
Query: 130 NQYRHYWSENLFQCFNCSLCLNGT-VHLSCQEKQNTVC-TCHAGFFLRE----NECVSCS 183
Y +Y E +C C +C G+ + SCQ+KQNTVC C G + E + C+ C+
Sbjct: 111 --YGYYQDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCT 168
Query: 184 NC----KKSLECTKLCLPQIENVKG 204
C ++ ECT+ + E + G
Sbjct: 169 VCEDTERQLRECTRWADAECEEIPG 193
>gi|23200031 tumor necrosis factor receptor superfamily, member 25
isoform 7 precursor [Homo sapiens]
Length = 234
Score = 70.9 bits (172), Expect = 2e-12
Identities = 62/201 (30%), Positives = 86/201 (42%), Gaps = 12/201 (5%)
Query: 242 KLYSIVCGKSTPEKEGELEGTTTKPLAPNPSFSPTPGFTPTLGFSPVPSSTFTSSSTYTP 301
K + C + P E +E T P SP TL P S +
Sbjct: 41 KKIGLFCCRGCPADEAGMEALTPPPAT---HLSPLDS-AHTLLAPPDSSEKICTVQLVGN 96
Query: 302 GDCPNFAAPRREVAPPYQGA-DPILATALASDPIPNPLQKWEDSAHKPQSLDTDDPATLY 360
P + + + P + D + + AL P P E A P + P LY
Sbjct: 97 SWTPGYPETQEALCPQVTWSWDQLPSRALG--PAAAPTLSPESPAGSPAMMLQPGPQ-LY 153
Query: 361 AVVENVPPLRWKEFVRRLGLSDHEIDRLELQNGRCLREAQYSMLATWRRRTPRREATLEL 420
V++ VP RWKEFVR LGL + EI+ +E++ GR R+ QY ML WR++ P A L
Sbjct: 154 DVMDAVPARRWKEFVRTLGLREAEIEAVEVEIGR-FRDQQYEMLKRWRQQQP---AGLGA 209
Query: 421 LGRVLRDMDLLGCLEDIEEAL 441
+ L M L GC+ED+ L
Sbjct: 210 VYAALERMGLDGCVEDLRSRL 230
>gi|148743793 osteoprotegerin precursor [Homo sapiens]
Length = 401
Score = 60.1 bits (144), Expect = 4e-09
Identities = 49/166 (29%), Positives = 71/166 (42%), Gaps = 14/166 (8%)
Query: 48 KYIH---PQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSK 104
KY+H ++ + C KC GTYL C + T C C +T S + CL CS
Sbjct: 27 KYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWK-TVCAPCPDHYYTDSWHTSDECLYCSP 85
Query: 105 CRKEMGQVEISSCTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCLNG-TVHLSCQEKQN 163
KE+ V+ C + VC C++ +Y + C C G V + ++N
Sbjct: 86 VCKELQYVK-QECNRTHNRVCECKEGRYL-----EIEFCLKHRSCPPGFGVVQAGTPERN 139
Query: 164 TVC-TCHAGFFLRENECVSCSNCKKSLECTKLCLPQIENVKGTEDS 208
TVC C GFF NE S + C+K C+ L + T D+
Sbjct: 140 TVCKRCPDGFF--SNETSSKAPCRKHTNCSVFGLLLTQKGNATHDN 183
>gi|224494019 tumor necrosis factor receptor superfamily, member 10b
isoform 1 precursor [Homo sapiens]
Length = 440
Score = 58.9 bits (141), Expect = 9e-09
Identities = 101/434 (23%), Positives = 161/434 (37%), Gaps = 82/434 (18%)
Query: 6 VPDLLLPLVLLELLVGIYPSGVIGLVPHLGDREKRDSVCPQGKYIHPQNNSICCTKCHKG 65
VP L+ +V LL+ S +I D + PQ K P C G
Sbjct: 34 VPKTLVLVVAAVLLLVSAESALITQQ----DLAPQQRAAPQQKRSSPSEGL-----CPPG 84
Query: 66 TYLYNDCPGPGQDTDCRECESGS-FTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTV 124
++ D DC C+ G ++ N L CL C++C + G+VE+S CT R+TV
Sbjct: 85 HHISED------GRDCISCKYGQDYSTHWNDLLFCLRCTRC--DSGEVELSPCTTTRNTV 136
Query: 125 CGCRKNQYRHYWSENLFQCFNCSL-CLNGTVHL-SCQEKQNTVC------TCHAGFFLRE 176
C C + +R S + C C C G V + C + C T H+G
Sbjct: 137 CQCEEGTFREEDSPEM--CRKCRTGCPRGMVKVGDCTPWSDIECVHKESGTKHSGEVPAV 194
Query: 177 NECVSCSNCKKSLECTKLCLPQIENVKGTEDSGTTVLLPLVIFFGLCLLSLLFIGLMYRY 236
E V+ S + C ++ G T + L++ +C SLL
Sbjct: 195 EETVTSSPGTPASPC---------SLSGIIIGVTVAAVVLIVAVFVC-KSLL-------- 236
Query: 237 QRWKSKLYSI--VC--GKSTPEKEGELEGTTTKPLAPNPSFSP-----TPGFTPTLGFSP 287
WK L + +C G PE+ ++ ++ +P A + + P P
Sbjct: 237 --WKKVLPYLKGICSGGGGDPER---VDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEV 291
Query: 288 VPSSTFTSSSTYTPGDCPNFAAPRREVAPPYQGADPILATALASDPIPNPLQKWEDSAHK 347
+ T + +PG+ + P + +L A DP Q ++D A
Sbjct: 292 QEPAEPTGVNMLSPGESEHLLEPAEAERSQRR---RLLVPANEGDPTETLRQCFDDFA-- 346
Query: 348 PQSLDTDDPATLYAVVENVPPLRWKEFVRRLGLSDHEIDRLELQNGRCLREAQYSMLATW 407
+ VP W+ +R+LGL D+EI ++ R+ Y+ML W
Sbjct: 347 ----------------DLVPFDSWEPLMRKLGLMDNEI-KVAKAEAAGHRDTLYTMLIKW 389
Query: 408 RRRTPRREATLELL 421
+T R + LL
Sbjct: 390 VNKTGRDASVHTLL 403
>gi|4507577 tumor necrosis factor receptor 2 precursor [Homo
sapiens]
Length = 461
Score = 58.5 bits (140), Expect = 1e-08
Identities = 48/165 (29%), Positives = 68/165 (41%), Gaps = 20/165 (12%)
Query: 42 SVCPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLS 101
S C +Y + Q +CC+KC G + C DT C CE ++T N + CLS
Sbjct: 38 STCRLREY-YDQTAQMCCSKCSPGQHAKVFCT-KTSDTVCDSCEDSTYTQLWNWVPECLS 95
Query: 102 C-SKCRKEMGQVEISSCTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCL-------NGT 153
C S+C + QVE +CT +++ +C CR W L + C LC
Sbjct: 96 CGSRCSSD--QVETQACTREQNRICTCRPG-----WYCALSKQEGCRLCAPLRKCRPGFG 148
Query: 154 VHLSCQEKQNTVC-TCHAGFFLRENECVSCSNCKKSLECTKLCLP 197
V E + VC C G F N S C+ C + +P
Sbjct: 149 VARPGTETSDVVCKPCAPGTF--SNTTSSTDICRPHQICNVVAIP 191
Score = 49.3 bits (116), Expect = 7e-06
Identities = 38/122 (31%), Positives = 54/122 (44%), Gaps = 15/122 (12%)
Query: 73 PGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTVC-GCRKNQ 131
P PG + CR E TA + CSKC GQ CT DTVC C +
Sbjct: 34 PEPG--STCRLREYYDQTAQ-------MCCSKCSP--GQHAKVFCTKTSDTVCDSCEDST 82
Query: 132 YRHYWSENLFQCFNC-SLCLNGTVHL-SCQEKQNTVCTCHAGFFLRENECVSCSNCKKSL 189
Y W+ + +C +C S C + V +C +QN +CTC G++ ++ C C
Sbjct: 83 YTQLWNW-VPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLR 141
Query: 190 EC 191
+C
Sbjct: 142 KC 143
>gi|224494026 tumor necrosis factor receptor superfamily, member 10b
isoform 2 precursor [Homo sapiens]
Length = 411
Score = 54.7 bits (130), Expect = 2e-07
Identities = 96/426 (22%), Positives = 155/426 (36%), Gaps = 95/426 (22%)
Query: 6 VPDLLLPLVLLELLVGIYPSGVIGLVPHLGDREKRDSVCPQGKYIHPQNNSICCTKCHKG 65
VP L+ +V LL+ S +I D + PQ K P C G
Sbjct: 34 VPKTLVLVVAAVLLLVSAESALITQQ----DLAPQQRAAPQQKRSSPSEGL-----CPPG 84
Query: 66 TYLYNDCPGPGQDTDCRECESGS-FTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTV 124
++ D DC C+ G ++ N L CL C++C + G+VE+S CT R+TV
Sbjct: 85 HHISED------GRDCISCKYGQDYSTHWNDLLFCLRCTRC--DSGEVELSPCTTTRNTV 136
Query: 125 CGCRKNQYRHYWSENLFQCFNCSLCLNGTVHLSCQEKQNTVCTCHAGFFLRENECVSCSN 184
C C + +R S + C C G C G ++ +C S+
Sbjct: 137 CQCEEGTFREEDSPEM-----CRKCRTG---------------CPRG-MVKVGDCTPWSD 175
Query: 185 CKKSLECTKLCLPQIENVKGTEDSGTTVLLPLVIFFGLCLLSLLFIGLMYRYQRWKSKLY 244
+EC + G T + L++ +C SLL WK L
Sbjct: 176 ----IEC-------VHKESGIIIGVTVAAVVLIVAVFVC-KSLL----------WKKVLP 213
Query: 245 SI--VC--GKSTPEKEGELEGTTTKPLAPNPSFSP-----TPGFTPTLGFSPVPSSTFTS 295
+ +C G PE+ ++ ++ +P A + + P P + T
Sbjct: 214 YLKGICSGGGGDPER---VDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTG 270
Query: 296 SSTYTPGDCPNFAAPRREVAPPYQGADPILATALASDPIPNPLQKWEDSAHKPQSLDTDD 355
+ +PG+ + P + +L A DP Q ++D A
Sbjct: 271 VNMLSPGESEHLLEPAEAERSQRR---RLLVPANEGDPTETLRQCFDDFA---------- 317
Query: 356 PATLYAVVENVPPLRWKEFVRRLGLSDHEIDRLELQNGRCLREAQYSMLATWRRRTPRRE 415
+ VP W+ +R+LGL D+EI ++ R+ Y+ML W +T R
Sbjct: 318 --------DLVPFDSWEPLMRKLGLMDNEI-KVAKAEAAGHRDTLYTMLIKWVNKTGRDA 368
Query: 416 ATLELL 421
+ LL
Sbjct: 369 SVHTLL 374
>gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]
Length = 277
Score = 54.3 bits (129), Expect = 2e-07
Identities = 54/199 (27%), Positives = 82/199 (41%), Gaps = 17/199 (8%)
Query: 42 SVCPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLS 101
+ C + +Y+ NS CC+ C G L +DC +T+C C F + N HC
Sbjct: 24 TACREKQYLI---NSQCCSLCQPGQKLVSDCT-EFTETECLPCGESEFLDTWNRETHCHQ 79
Query: 102 CSKCRKEMGQVEISSCTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCLNG-TVHLSCQE 160
C +G T + DT+C C + H SE C C G V
Sbjct: 80 HKYCDPNLGLRVQQKGTSETDTICTCEEGW--HCTSEACESCVLHRSCSPGFGVKQIATG 137
Query: 161 KQNTVC-TCHAGFFLREN----ECVSCSNCK-KSLECTKLCLPQIENVKGTEDSGTTVLL 214
+T+C C GFF + +C ++C+ K L + + + V G +D L+
Sbjct: 138 VSDTICEPCPVGFFSNVSSAFEKCHPWTSCETKDLVVQQAGTNKTDVVCGPQDR-LRALV 196
Query: 215 PLVIFFGL---CLLSLLFI 230
+ I FG+ LL L+FI
Sbjct: 197 VIPIIFGILFAILLVLVFI 215
>gi|22547121 tumor necrosis factor receptor superfamily, member 10c
precursor [Homo sapiens]
Length = 259
Score = 54.3 bits (129), Expect = 2e-07
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 9/92 (9%)
Query: 71 DCPGPGQDTD----CRECESG-SFTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTVC 125
+CP ++ C C G +T + N+ C C+ C+ + Q SSCT+ RDTVC
Sbjct: 52 ECPAGSHRSEHTGACNPCTEGVDYTNASNNEPSCFPCTVCKSD--QKHKSSCTMTRDTVC 109
Query: 126 GCRKNQYRHYWSENLFQCFNCSLCLNGTVHLS 157
C++ +R+ S + C CS C +G V +S
Sbjct: 110 QCKEGTFRNENSPEM--CRKCSRCPSGEVQVS 139
Score = 40.4 bits (93), Expect = 0.003
Identities = 21/53 (39%), Positives = 26/53 (49%), Gaps = 4/53 (7%)
Query: 137 SENLFQCFNCSLCLNGTVHLS-CQEKQNTVCTCHAGFFLRENE---CVSCSNC 185
S N CF C++C + H S C ++TVC C G F EN C CS C
Sbjct: 79 SNNEPSCFPCTVCKSDQKHKSSCTMTRDTVCQCKEGTFRNENSPEMCRKCSRC 131
>gi|4507587 tumor necrosis factor receptor superfamily, member 7
precursor [Homo sapiens]
Length = 260
Score = 53.9 bits (128), Expect = 3e-07
Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 11/104 (10%)
Query: 44 CPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLR-HCLSC 102
CP+ Y +CC C GT+L DC + C C G + ++H R HC SC
Sbjct: 27 CPERHYW--AQGKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESC 84
Query: 103 SKCRKEMGQVEISSCTVDRDTVCGCRKNQYRHYWSENLFQCFNC 146
C + + +CT+ + C CR W +C C
Sbjct: 85 RHCNSGL---LVRNCTITANAECACRNG-----WQCRDKECTEC 120
>gi|22547108 tumor necrosis factor receptor superfamily, member 10d
precursor [Homo sapiens]
Length = 386
Score = 53.9 bits (128), Expect = 3e-07
Identities = 34/103 (33%), Positives = 48/103 (46%), Gaps = 11/103 (10%)
Query: 71 DCPGPGQDTD----CRECESG-SFTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTVC 125
+CP ++ C C G +T + N+L CL C+ C+ GQ SSCT RDTVC
Sbjct: 82 ECPAGSHRSEYTGACNPCTEGVDYTIASNNLPSCLLCTVCKS--GQTNKSSCTTTRDTVC 139
Query: 126 GCRKNQYRHYWSENLFQCFNCSL-CLNGTVHLS-CQEKQNTVC 166
C K ++ S + C C C G V +S C + + C
Sbjct: 140 QCEKGSFQDKNSPEM--CRTCRTGCPRGMVKVSNCTPRSDIKC 180
Score = 40.0 bits (92), Expect = 0.004
Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 9/84 (10%)
Query: 137 SENLFQCFNCSLCLNG-TVHLSCQEKQNTVCTCHAGFFLRENECVSCSNCK--------K 187
S NL C C++C +G T SC ++TVC C G F +N C C+ K
Sbjct: 109 SNNLPSCLLCTVCKSGQTNKSSCTTTRDTVCQCEKGSFQDKNSPEMCRTCRTGCPRGMVK 168
Query: 188 SLECTKLCLPQIENVKGTEDSGTT 211
CT + +N +G T
Sbjct: 169 VSNCTPRSDIKCKNESAASSTGKT 192
>gi|23200041 tumor necrosis factor receptor superfamily, member 14
precursor [Homo sapiens]
Length = 283
Score = 53.1 bits (126), Expect = 5e-07
Identities = 38/137 (27%), Positives = 50/137 (36%), Gaps = 8/137 (5%)
Query: 56 SICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEIS 115
S CC KC G Y + G T C C G++ A N L CL C C MG
Sbjct: 51 SECCPKCSPG-YRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRASR 109
Query: 116 SCTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCLNGT----VHLSCQEKQNTVC-TCHA 170
+C+ + VCGC + + C C + V E Q+T+C C
Sbjct: 110 NCSRTENAVCGCSPGHFCIVQDGD--HCAACRAYATSSPGQRVQKGGTESQDTLCQNCPP 167
Query: 171 GFFLRENECVSCSNCKK 187
G F C + K
Sbjct: 168 GTFSPNGTLEECQHQTK 184
>gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]
Length = 203
Score = 50.4 bits (119), Expect = 3e-06
Identities = 38/134 (28%), Positives = 53/134 (39%), Gaps = 8/134 (5%)
Query: 42 SVCPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLS 101
+ C + +Y+ NS CC+ C G L +DC +T+C C F + N HC
Sbjct: 24 TACREKQYLI---NSQCCSLCQPGQKLVSDCT-EFTETECLPCGESEFLDTWNRETHCHQ 79
Query: 102 CSKCRKEMGQVEISSCTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCLNG-TVHLSCQE 160
C +G T + DT+C C + H SE C C G V
Sbjct: 80 HKYCDPNLGLRVQQKGTSETDTICTCEEGW--HCTSEACESCVLHRSCSPGFGVKQIATG 137
Query: 161 KQNTVC-TCHAGFF 173
+T+C C GFF
Sbjct: 138 VSDTICEPCPVGFF 151
Score = 40.4 bits (93), Expect = 0.003
Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 18/113 (15%)
Query: 75 PGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTVC-GCRKNQYR 133
P T CRE + +L + CS C+ GQ +S CT +T C C ++++
Sbjct: 20 PEPPTACRE---------KQYLINSQCCSLCQP--GQKLVSDCTEFTETECLPCGESEFL 68
Query: 134 HYWSENLFQCFNCSLCLNGTVHLSCQEK----QNTVCTCHAGFFLRENECVSC 182
W+ C C + + L Q+K +T+CTC G+ C SC
Sbjct: 69 DTWNRET-HCHQHKYC-DPNLGLRVQQKGTSETDTICTCEEGWHCTSEACESC 119
>gi|4507565 tumor necrosis factor receptor superfamily, member 11a
precursor [Homo sapiens]
Length = 616
Score = 50.1 bits (118), Expect = 4e-06
Identities = 56/233 (24%), Positives = 92/233 (39%), Gaps = 36/233 (15%)
Query: 51 HPQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMG 110
H ++ CC KC G Y+ + C D+ C C + S N CL C
Sbjct: 39 HYEHLGRCCNKCEPGKYMSSKCT-TTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKA 97
Query: 111 QVEISSCTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCLNGT-VHLSCQEKQNTVC-TC 168
V + + C C ++WS++ C + C G Q ++TVC C
Sbjct: 98 LVAVVAGNSTTPRRCACTAG---YHWSQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPC 154
Query: 169 HAGFFLRENECVSCSNCKKSLECTKLCLPQIENVKGTEDSGTT---------------VL 213
AG+F + S C+ CT L ++E+ GTE S V
Sbjct: 155 LAGYF--SDAFSSTDKCRPWTNCTFLG-KRVEH-HGTEKSDAVCSSSLPARKPPNEPHVY 210
Query: 214 LP----LVIFFGLCLLSLLFIGLMYRYQRWKSKLYSI------VCGKSTPEKE 256
LP L++F + L++ + G+ YR ++ K+ ++ CG+ + +KE
Sbjct: 211 LPGLIILLLFASVALVAAIIFGVCYR-KKGKALTANLWHWINEACGRLSGDKE 262
>gi|23510423 tumor necrosis factor receptor superfamily, member 6
isoform 3 precursor [Homo sapiens]
Length = 220
Score = 49.3 bits (116), Expect = 7e-06
Identities = 57/223 (25%), Positives = 69/223 (30%), Gaps = 68/223 (30%)
Query: 54 NNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVE 113
+ C C G DC G + DC C+ G + H SKCR+
Sbjct: 55 DGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFS-----SKCRR------ 103
Query: 114 ISSCTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCLNG---TVHLSCQEKQNTVCTCHA 170
C LC G V ++C QNT C C
Sbjct: 104 --------------------------------CRLCDEGHGLEVEINCTRTQNTKCRCKP 131
Query: 171 GFFLRENECVSCSNCKKS-----LECTKLCLPQIENVKGTEDSGTTVLLPLVIFFGLCLL 225
FF C C C K ECT N K E+ + L LCLL
Sbjct: 132 NFFCNSTVCEHCDPCTKCEHGIIKECT-----LTSNTKCKEEGSRSNL------GWLCLL 180
Query: 226 SLLFIGLMYRYQRW-KSKLYSIVCGKSTPEKEGELEGTTTKPL 267
LL I L+ W K K C K E +G E T P+
Sbjct: 181 -LLPIPLIV----WVKRKEVQKTCRKHRKENQGSHESPTLNPM 218
>gi|4507583 tumor necrosis factor receptor superfamily, member 6
isoform 1 precursor [Homo sapiens]
Length = 335
Score = 48.5 bits (114), Expect = 1e-05
Identities = 57/222 (25%), Positives = 68/222 (30%), Gaps = 68/222 (30%)
Query: 54 NNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVE 113
+ C C G DC G + DC C+ G + H SKCR+
Sbjct: 55 DGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFS-----SKCRR------ 103
Query: 114 ISSCTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCLNG---TVHLSCQEKQNTVCTCHA 170
C LC G V ++C QNT C C
Sbjct: 104 --------------------------------CRLCDEGHGLEVEINCTRTQNTKCRCKP 131
Query: 171 GFFLRENECVSCSNCKKS-----LECTKLCLPQIENVKGTEDSGTTVLLPLVIFFGLCLL 225
FF C C C K ECT N K E+ + L LCLL
Sbjct: 132 NFFCNSTVCEHCDPCTKCEHGIIKECT-----LTSNTKCKEEGSRSNL------GWLCLL 180
Query: 226 SLLFIGLMYRYQRW-KSKLYSIVCGKSTPEKEGELEGTTTKP 266
LL I L+ W K K C K E +G E T P
Sbjct: 181 -LLPIPLIV----WVKRKEVQKTCRKHRKENQGSHESPTLNP 217
Score = 29.3 bits (64), Expect = 7.7
Identities = 18/67 (26%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
Query: 372 KEFVRRLGLSDHEIDRLELQNGRCLREAQYSMLATWRRRTPRREATLELLGRVLRDMDLL 431
K FVR+ G+++ +ID ++ N + E + +L W + ++EA + L + L+ +L
Sbjct: 246 KGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGKKEA-YDTLIKDLKKANLC 304
Query: 432 GCLEDIE 438
E I+
Sbjct: 305 TLAEKIQ 311
>gi|68348711 tumor necrosis factor receptor superfamily, member 8
isoform 1 precursor [Homo sapiens]
Length = 595
Score = 48.5 bits (114), Expect = 1e-05
Identities = 50/178 (28%), Positives = 75/178 (42%), Gaps = 16/178 (8%)
Query: 14 VLLELLVGIYPSGVIGLVPHLGDREKRDSVCPQGKYIHPQNNSICCTKCHKGTYLYNDCP 73
VLL L G+ G + P DR D+ + + + CC +C G + C
Sbjct: 3 VLLAAL-GLLFLGALRAFPQ--DRPFEDTCHGNPSHYYDKAVRRCCYRCPMGLFPTQQC- 58
Query: 74 GPGQDTDCR-ECESGSFTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTVCGCRKNQY 132
P + TDCR +CE + + C++CS R ++ VE + C + VC CR +
Sbjct: 59 -PQRPTDCRKQCEPDYYLDEADRCTACVTCS--RDDL--VEKTPCAWNSSRVCECRPGMF 113
Query: 133 RHYWSEN-LFQCFNCSLCLNG-TVHLSCQEKQNTVC-TCHAGFFLRENECVSCSNCKK 187
+ N +CF S+C G V ++NTVC G C S NCK+
Sbjct: 114 CSTSAVNSCARCFFHSVCPAGMIVKFPGTAQKNTVCEPASPGV---SPACASPENCKE 168
>gi|21361086 tumor necrosis factor receptor superfamily, member 10a
[Homo sapiens]
Length = 468
Score = 48.1 bits (113), Expect = 2e-05
Identities = 94/444 (21%), Positives = 151/444 (34%), Gaps = 106/444 (23%)
Query: 14 VLLELLVGIYPSGVIGLVPHLGDREKRDSVCPQGKYIHPQNNSICCTKCHKGTYLYNDCP 73
V++ +L+ + PS + H D ++ H +C H+ +
Sbjct: 95 VVVGVLLQVVPSSAATIKLH-------DQSIGTQQWEHSPLGELCPPGSHRSEH------ 141
Query: 74 GPGQDTDCRECESG-SFTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTVCGCRKNQY 132
PG C C G +T + N+L CL C+ C+ + + E S CT R+T C C+ +
Sbjct: 142 -PGA---CNRCTEGVGYTNASNNLFACLPCTACKSD--EEERSPCTTTRNTACQCKPGTF 195
Query: 133 RHYWSENLFQCFNCSLCLNGTVHLSCQEKQNTVCTCHAGFFLRENECVSCSNCKKSLECT 192
R+ S + C C G C + +
Sbjct: 196 RNDNSAEM-----CRKCSRG--------------------------------CPRGMVKV 218
Query: 193 KLCLP--QIENVKGTEDSGTT--VLLPLVIFFGLCLLSLLFIGLMYRYQ-RWKSKLYSIV 247
K C P IE V +G V+L + + L L+++L + K V
Sbjct: 219 KDCTPWSDIECVHKESGNGHNIWVILVVTLVVPLLLVAVLIVCCCIGSGCGGDPKCMDRV 278
Query: 248 CGKSTPEKEGELEGTTTKPLAPNPSFSPTPGFTPTLGFSPVPS---STFTSSSTYTPGDC 304
C + G L G + A N S + + + S + T + +PG+
Sbjct: 279 CF----WRLGLLRGPGAEDNAHNEILSNADSLSTFVSEQQMESQEPADLTGVTVQSPGEA 334
Query: 305 PNFAAP-------RREVAPPYQGADPILATALASDPIPNPLQKWEDSAHKPQSLDTDDPA 357
P RR + P GADP L D N
Sbjct: 335 QCLLGPAEAEGSQRRRLLVPANGADPTETLMLFFDKFAN--------------------- 373
Query: 358 TLYAVVENVPPLRWKEFVRRLGLSDHEIDRLELQNGRCLREAQYSMLATWRRRTPRREAT 417
VP W + +R+L L+ +EID + +A Y+ML W +T R A+
Sbjct: 374 -------IVPFDSWDQLMRQLDLTKNEIDVVRAGTAG-PGDALYAMLMKWVNKT-GRNAS 424
Query: 418 LELLGRVLRDMDLLGCLEDIEEAL 441
+ L L M+ E I++ L
Sbjct: 425 IHTLLDALERMEERHAKEKIQDLL 448
>gi|11140823 X-linked ectodysplasin receptor [Homo sapiens]
Length = 297
Score = 48.1 bits (113), Expect = 2e-05
Identities = 72/309 (23%), Positives = 107/309 (34%), Gaps = 65/309 (21%)
Query: 44 CPQGKYIHPQNNSICCTKCHKGTYLYNDCP-GPGQDTDCRECESGSFTASENHLRHCLSC 102
C + +Y + C +C G L DC G G D C C + +S H R C SC
Sbjct: 3 CQENEYWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHR-CQSC 61
Query: 103 SKCRKEMGQVEISSCTVDRDTVCG-CRKNQYRHYWSENLFQCFNCSLCLNGTVHLSCQEK 161
C + +V+ +CT + VCG C YR + G
Sbjct: 62 ITC-AVINRVQKVNCTATSNAVCGDCLPRFYR-------------KTRIGG--------- 98
Query: 162 QNTVCTCHAGFFLRENECVSCSNCKKSLE---CTKLCLPQIENVKGTEDSGTTVLL--PL 216
L++ EC+ C+ + E +L L + + T V L L
Sbjct: 99 ------------LQDQECIPCTKQTPTSEVQCAFQLSLVEADAPTVPPQEATLVALVSSL 146
Query: 217 VIFFGLCLLSLLFIGLMYRYQR--WKSKLYSIVCGKST---------PEKEGELEGTT-- 263
++ F L L L F+ + R + L K+ P KE E
Sbjct: 147 LVVFTLAFLGLFFLYCKQFFNRHCQRGGLLQFEADKTAKEESLFPVPPSKETSAESQVSE 206
Query: 264 ----TKPLAP--NPSFSPTPGFTPTLGFSPVPSSTFTSSS--TYTPGDCPNFAAPRREVA 315
T+PL P S T GF PT + S T S S ++P +C + +
Sbjct: 207 NIFQTQPLNPILEDDCSSTSGF-PTQESFTMASCTSESHSHWVHSPIECTELDLQKFSSS 265
Query: 316 PPYQGADPI 324
Y GA+ +
Sbjct: 266 ASYTGAETL 274
>gi|23510421 tumor necrosis factor receptor superfamily, member 6
isoform 2 precursor [Homo sapiens]
Length = 314
Score = 47.8 bits (112), Expect = 2e-05
Identities = 33/115 (28%), Positives = 49/115 (42%), Gaps = 6/115 (5%)
Query: 54 NNSICCTKCHKGTYLYNDCPGPGQDTDCRECESG-SFTASENHLRHCLSCSKCRKEMG-Q 111
+ C C G DC G + DC C+ G +T + C C C + G +
Sbjct: 55 DGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLE 114
Query: 112 VEISSCTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCLNGTVHLSCQEKQNTVC 166
VEI +CT ++T C C+ N + + S C C+ C +G + C NT C
Sbjct: 115 VEI-NCTRTQNTKCRCKPNFFCN--STVCEHCDPCTKCEHGIIK-ECTLTSNTKC 165
Score = 29.3 bits (64), Expect = 7.7
Identities = 18/67 (26%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
Query: 372 KEFVRRLGLSDHEIDRLELQNGRCLREAQYSMLATWRRRTPRREATLELLGRVLRDMDLL 431
K FVR+ G+++ +ID ++ N + E + +L W + ++EA + L + L+ +L
Sbjct: 225 KGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGKKEA-YDTLIKDLKKANLC 283
Query: 432 GCLEDIE 438
E I+
Sbjct: 284 TLAEKIQ 290
>gi|4507579 tumor necrosis factor receptor superfamily, member 4
precursor [Homo sapiens]
Length = 277
Score = 47.4 bits (111), Expect = 3e-05
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Query: 54 NNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVE 113
+N CC +C G + + C Q+T CR C G + + + C C+ C G
Sbjct: 38 SNDRCCHECRPGNGMVSRC-SRSQNTVCRPCGPGFYNDVVSS-KPCKPCTWCNLRSGSER 95
Query: 114 ISSCTVDRDTVCGCR 128
CT +DTVC CR
Sbjct: 96 KQLCTATQDTVCRCR 110
Score = 33.5 bits (75), Expect = 0.41
Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 102 CSKCRKEMGQVEISSCTVDRDTVCG-CRKNQYRHYWSENLFQ-CFNCSLCLNGTVHLSCQ 159
C +CR G V S C+ ++TVC C Y S + C C+L C
Sbjct: 43 CHECRPGNGMV--SRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGSERKQLCT 100
Query: 160 EKQNTVCTCHAG 171
Q+TVC C AG
Sbjct: 101 ATQDTVCRCRAG 112
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 45.8 bits (107), Expect = 8e-05
Identities = 43/150 (28%), Positives = 63/150 (42%), Gaps = 21/150 (14%)
Query: 43 VCPQG---KYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHC 99
+CP G +YIH +N S C +C +GTY Y+ G +T C C G++ R C
Sbjct: 1034 LCPSGMYTEYIHSRNISDCKAQCKQGTYSYS-----GLET-CESCPLGTYQPKFGS-RSC 1086
Query: 100 LSC--SKCRKEMGQVEISSCTV-------DRDTVCGCRKNQYRHYWSENLFQCFNCSLCL 150
LSC + + G V IS+C V R + C R Y+ N + F +
Sbjct: 1087 LSCPENTSTVKRGAVNISACGVPCPEGKFSRSGLMPCHPCP-RDYYQPNAGKAFCLACPF 1145
Query: 151 NGTVHLSCQEKQNTVCTCHAGFFLRENECV 180
GT + + T C+ + F E V
Sbjct: 1146 YGTTPFA-GSRSITECSSFSSTFSAAEESV 1174
>gi|14790170 tumor necrosis factor receptor superfamily, member 6b
[Homo sapiens]
Length = 300
Score = 43.5 bits (101), Expect = 4e-04
Identities = 41/156 (26%), Positives = 56/156 (35%), Gaps = 13/156 (8%)
Query: 57 ICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISS 116
+ C +C GT++ C T C C +T N+L C C+ E + E +
Sbjct: 47 LVCAQCPPGTFVQRPCRRDSPTT-CGPCPPRHYTQFWNYLERCRYCNVLCGER-EEEARA 104
Query: 117 CTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCLNGT-VHLSCQEKQNTVC-TCHAGFFL 174
C + C CR + H C + C G V QNT C C G F
Sbjct: 105 CHATHNRACRCRTGFFAHAGF-----CLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFS 159
Query: 175 RENECVSCSNCKKSLECTKLCLPQIENVKGTEDSGT 210
+ S C+ CT L L NV G+ T
Sbjct: 160 ASSS--SSEQCQPHRNCTALGLAL--NVPGSSSHDT 191
Score = 32.3 bits (72), Expect = 0.91
Identities = 22/87 (25%), Positives = 33/87 (37%), Gaps = 24/87 (27%)
Query: 35 GDREKRDSVCPQGKYIHPQNNSICCTKCHKGTYLYN-------DCPG---------PGQD 78
G+RE+ C H +N C +C G + + CP P Q+
Sbjct: 96 GEREEEARAC------HATHNRAC--RCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQN 147
Query: 79 TDCRECESGSFTASENHLRHCLSCSKC 105
T C+ C G+F+AS + C C
Sbjct: 148 TQCQPCPPGTFSASSSSSEQCQPHRNC 174
>gi|4507585 tumor necrosis factor receptor superfamily, member 6b
[Homo sapiens]
Length = 300
Score = 43.5 bits (101), Expect = 4e-04
Identities = 41/156 (26%), Positives = 56/156 (35%), Gaps = 13/156 (8%)
Query: 57 ICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISS 116
+ C +C GT++ C T C C +T N+L C C+ E + E +
Sbjct: 47 LVCAQCPPGTFVQRPCRRDSPTT-CGPCPPRHYTQFWNYLERCRYCNVLCGER-EEEARA 104
Query: 117 CTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCLNGT-VHLSCQEKQNTVC-TCHAGFFL 174
C + C CR + H C + C G V QNT C C G F
Sbjct: 105 CHATHNRACRCRTGFFAHAGF-----CLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFS 159
Query: 175 RENECVSCSNCKKSLECTKLCLPQIENVKGTEDSGT 210
+ S C+ CT L L NV G+ T
Sbjct: 160 ASSS--SSEQCQPHRNCTALGLAL--NVPGSSSHDT 191
Score = 32.3 bits (72), Expect = 0.91
Identities = 22/87 (25%), Positives = 33/87 (37%), Gaps = 24/87 (27%)
Query: 35 GDREKRDSVCPQGKYIHPQNNSICCTKCHKGTYLYN-------DCPG---------PGQD 78
G+RE+ C H +N C +C G + + CP P Q+
Sbjct: 96 GEREEEARAC------HATHNRAC--RCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQN 147
Query: 79 TDCRECESGSFTASENHLRHCLSCSKC 105
T C+ C G+F+AS + C C
Sbjct: 148 TQCQPCPPGTFSASSSSSEQCQPHRNC 174
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.443
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,272,858
Number of Sequences: 37866
Number of extensions: 1267348
Number of successful extensions: 5927
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 63
Number of HSP's successfully gapped in prelim test: 196
Number of HSP's that attempted gapping in prelim test: 4907
Number of HSP's gapped (non-prelim): 976
length of query: 455
length of database: 18,247,518
effective HSP length: 106
effective length of query: 349
effective length of database: 14,233,722
effective search space: 4967568978
effective search space used: 4967568978
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.