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Search of human proteins with 4505039
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505039 lymphotoxin beta receptor [Homo sapiens]
(435 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505039 lymphotoxin beta receptor [Homo sapiens] 942 0.0
gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens] 118 9e-27
gi|4507577 tumor necrosis factor receptor 2 precursor [Homo sapi... 117 2e-26
gi|14790170 tumor necrosis factor receptor superfamily, member 6... 115 1e-25
gi|4507585 tumor necrosis factor receptor superfamily, member 6b... 115 1e-25
gi|4507565 tumor necrosis factor receptor superfamily, member 11... 109 4e-24
gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens] 99 8e-21
gi|148743793 osteoprotegerin precursor [Homo sapiens] 94 3e-19
gi|23200041 tumor necrosis factor receptor superfamily, member 1... 89 8e-18
gi|7657039 tumor necrosis factor receptor superfamily, member 21... 86 7e-17
gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapi... 80 4e-15
gi|68348711 tumor necrosis factor receptor superfamily, member 8... 79 6e-15
gi|4507579 tumor necrosis factor receptor superfamily, member 4 ... 74 2e-13
gi|5730095 tumor necrosis factor receptor superfamily, member 9 ... 72 1e-12
gi|23510421 tumor necrosis factor receptor superfamily, member 6... 69 8e-12
gi|23510423 tumor necrosis factor receptor superfamily, member 6... 68 1e-11
gi|4507583 tumor necrosis factor receptor superfamily, member 6 ... 68 1e-11
gi|224494019 tumor necrosis factor receptor superfamily, member ... 62 1e-09
gi|224494026 tumor necrosis factor receptor superfamily, member ... 57 3e-08
gi|4507587 tumor necrosis factor receptor superfamily, member 7 ... 54 3e-07
gi|4505393 nerve growth factor receptor precursor [Homo sapiens] 54 4e-07
gi|23200023 tumor necrosis factor receptor superfamily, member 2... 54 4e-07
gi|23200021 tumor necrosis factor receptor superfamily, member 2... 54 4e-07
gi|89142745 tumor necrosis factor receptor superfamily, member 2... 54 4e-07
gi|4507569 tumor necrosis factor receptor superfamily, member 25... 54 4e-07
gi|21361086 tumor necrosis factor receptor superfamily, member 1... 52 1e-06
gi|23238200 RELT tumor necrosis factor receptor precursor [Homo ... 49 9e-06
gi|21361873 RELT tumor necrosis factor receptor precursor [Homo ... 49 9e-06
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 47 3e-05
gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] 46 6e-05
>gi|4505039 lymphotoxin beta receptor [Homo sapiens]
Length = 435
Score = 942 bits (2434), Expect = 0.0
Identities = 435/435 (100%), Positives = 435/435 (100%)
Query: 1 MLLPWATSAPGLAWGPLVLGLFGLLAASQPQAVPPYASENQTCRDQEKEYYEPQHRICCS 60
MLLPWATSAPGLAWGPLVLGLFGLLAASQPQAVPPYASENQTCRDQEKEYYEPQHRICCS
Sbjct: 1 MLLPWATSAPGLAWGPLVLGLFGLLAASQPQAVPPYASENQTCRDQEKEYYEPQHRICCS 60
Query: 61 RCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKR 120
RCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKR
Sbjct: 61 RCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKR 120
Query: 121 KTQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSS 180
KTQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSS
Sbjct: 121 KTQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSS 180
Query: 181 PSARCQPHTRCENQGLVEAAPGTAQSDTTCKNPLEPLPPEMSGTMLMLAVLLPLAFFLLL 240
PSARCQPHTRCENQGLVEAAPGTAQSDTTCKNPLEPLPPEMSGTMLMLAVLLPLAFFLLL
Sbjct: 181 PSARCQPHTRCENQGLVEAAPGTAQSDTTCKNPLEPLPPEMSGTMLMLAVLLPLAFFLLL 240
Query: 241 ATVFSCIWKSHPSLCRKLGSLLKRRPQGEGPNPVAGSWEPPKAHPYFPDLVQPLLPISGD 300
ATVFSCIWKSHPSLCRKLGSLLKRRPQGEGPNPVAGSWEPPKAHPYFPDLVQPLLPISGD
Sbjct: 241 ATVFSCIWKSHPSLCRKLGSLLKRRPQGEGPNPVAGSWEPPKAHPYFPDLVQPLLPISGD 300
Query: 301 VSPVSTGLPAAPVLEAGVPQQQSPLDLTREPQLEPGEQSQVAHGTNGIHVTGGSMTITGN 360
VSPVSTGLPAAPVLEAGVPQQQSPLDLTREPQLEPGEQSQVAHGTNGIHVTGGSMTITGN
Sbjct: 301 VSPVSTGLPAAPVLEAGVPQQQSPLDLTREPQLEPGEQSQVAHGTNGIHVTGGSMTITGN 360
Query: 361 IYIYNGPVLGGPPGPGDLPATPEPPYPIPEEGDPGPPGLSTPHQEDGKAWHLAETEHCGA 420
IYIYNGPVLGGPPGPGDLPATPEPPYPIPEEGDPGPPGLSTPHQEDGKAWHLAETEHCGA
Sbjct: 361 IYIYNGPVLGGPPGPGDLPATPEPPYPIPEEGDPGPPGLSTPHQEDGKAWHLAETEHCGA 420
Query: 421 TPSNRGPRNQFITHD 435
TPSNRGPRNQFITHD
Sbjct: 421 TPSNRGPRNQFITHD 435
>gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]
Length = 277
Score = 118 bits (296), Expect = 9e-27
Identities = 90/294 (30%), Positives = 129/294 (43%), Gaps = 44/294 (14%)
Query: 16 PLVLGLFG-LLAASQPQAVPPYASENQTCRDQEKEYYEPQHRICCSRCPPGTYVSAKCSR 74
PL L+G LL A P+ PP A CR EK+Y CCS C PG + + C+
Sbjct: 5 PLQCVLWGCLLTAVHPE--PPTA-----CR--EKQYLINSQ--CCSLCQPGQKLVSDCTE 53
Query: 75 IRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKRKTQCRCQPGMFCAA 134
+T C C E+ + + WN T C + CDP +GL TS+ T C C+ G C +
Sbjct: 54 FTETECLPCGESEFLDTWNRETHCHQHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCTS 113
Query: 135 WALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSSPSARCQPHTRCENQ 194
A C C L C PG + + G + C PC G F N SS +C P T CE +
Sbjct: 114 EA--CESCVLHRSCSPGFGVK-QIATGVSDTICEPCPVGFFSNVSSAFEKCHPWTSCETK 170
Query: 195 GLVEAAPGTAQSDTTCKNPLEPLPPEMSGTMLMLAVLLPLAFFLLLATVFSCIWKSHPSL 254
LV GT ++D C P + ++++ ++ + F +LL VF
Sbjct: 171 DLVVQQAGTNKTDVVCG------PQDRLRALVVIPIIFGILFAILLVLVFI--------- 215
Query: 255 CRKLGSLLKRRPQGEGPNPVAGSWEPPKAHPYFPDLVQPLLPISGDVSPVSTGL 308
+ ++P + P+P EP + + FPD LP S +PV L
Sbjct: 216 -----KKVAKKPTNKAPHP---KQEPQEIN--FPD----DLPGSNTAAPVQETL 255
>gi|4507577 tumor necrosis factor receptor 2 precursor [Homo
sapiens]
Length = 461
Score = 117 bits (293), Expect = 2e-26
Identities = 76/215 (35%), Positives = 99/215 (46%), Gaps = 29/215 (13%)
Query: 9 APGLAWGPLVLGLFGLLAASQ---PQAVPPYASE-NQTCRDQEKEYYEPQHRICCSRCPP 64
AP W L +GL AA A PYA E TCR +EYY+ ++CCS+C P
Sbjct: 2 APVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCR--LREYYDQTAQMCCSKCSP 59
Query: 65 GTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCR---PCDPVMGLEEIAPCTSKRK 121
G + C++ DTVC +C +++Y + WN++ C C D V E CT ++
Sbjct: 60 GQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQV----ETQACTREQN 115
Query: 122 TQCRCQPGMFCAAWALE-CTHCELLSDCPPG-----TEAELKDEVGKGNNHCVPCKAGHF 175
C C+PG +CA E C C L C PG E D V C PC G F
Sbjct: 116 RICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVV------CKPCAPGTF 169
Query: 176 QNTSSPSARCQPHTRCENQGLVEAAPGTAQSDTTC 210
NT+S + C+PH C V A PG A D C
Sbjct: 170 SNTTSSTDICRPHQICN----VVAIPGNASMDAVC 200
>gi|14790170 tumor necrosis factor receptor superfamily, member 6b
[Homo sapiens]
Length = 300
Score = 115 bits (287), Expect = 1e-25
Identities = 88/274 (32%), Positives = 116/274 (42%), Gaps = 30/274 (10%)
Query: 6 ATSAPGLAWGPLVLGLFGLLAASQPQAVPPYASENQTCRDQEKEYYEPQHRICCSRCPPG 65
A PGL+ LVL L LL + V +E T ++ E E R+ C++CPPG
Sbjct: 3 ALEGPGLSLLCLVLALPALLPVPAVRGV----AETPTYPWRDAETGE---RLVCAQCPPG 55
Query: 66 TYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMG--LEEIAPCTSKRKTQ 123
T+V C R T C C Y + WNYL + CR C+ + G EE C +
Sbjct: 56 TFVQRPCRRDSPTTCGPCPPRHYTQFWNYL---ERCRYCNVLCGEREEEARACHATHNRA 112
Query: 124 CRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSSPSA 183
CRC+ G F A C + CPPG + N C PC G F +SS S
Sbjct: 113 CRCRTGFFAHA-----GFCLEHASCPPGA-GVIAPGTPSQNTQCQPCPPGTFSASSSSSE 166
Query: 184 RCQPHTRCENQGLVEAAPGTAQSDTTCKNPLE-PLPPEMSGTMLMLAVLLPLAFFLLLAT 242
+CQPH C GL PG++ DT C + PL + G ++ F +
Sbjct: 167 QCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDI-- 224
Query: 243 VFSCIWKSHPSLCRKLGSLLKRRPQGEGPNPVAG 276
S L R L +L P+G GP P AG
Sbjct: 225 -------SIKRLQRLLQAL--EAPEGWGPTPRAG 249
>gi|4507585 tumor necrosis factor receptor superfamily, member 6b
[Homo sapiens]
Length = 300
Score = 115 bits (287), Expect = 1e-25
Identities = 88/274 (32%), Positives = 116/274 (42%), Gaps = 30/274 (10%)
Query: 6 ATSAPGLAWGPLVLGLFGLLAASQPQAVPPYASENQTCRDQEKEYYEPQHRICCSRCPPG 65
A PGL+ LVL L LL + V +E T ++ E E R+ C++CPPG
Sbjct: 3 ALEGPGLSLLCLVLALPALLPVPAVRGV----AETPTYPWRDAETGE---RLVCAQCPPG 55
Query: 66 TYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMG--LEEIAPCTSKRKTQ 123
T+V C R T C C Y + WNYL + CR C+ + G EE C +
Sbjct: 56 TFVQRPCRRDSPTTCGPCPPRHYTQFWNYL---ERCRYCNVLCGEREEEARACHATHNRA 112
Query: 124 CRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSSPSA 183
CRC+ G F A C + CPPG + N C PC G F +SS S
Sbjct: 113 CRCRTGFFAHA-----GFCLEHASCPPGA-GVIAPGTPSQNTQCQPCPPGTFSASSSSSE 166
Query: 184 RCQPHTRCENQGLVEAAPGTAQSDTTCKNPLE-PLPPEMSGTMLMLAVLLPLAFFLLLAT 242
+CQPH C GL PG++ DT C + PL + G ++ F +
Sbjct: 167 QCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDI-- 224
Query: 243 VFSCIWKSHPSLCRKLGSLLKRRPQGEGPNPVAG 276
S L R L +L P+G GP P AG
Sbjct: 225 -------SIKRLQRLLQAL--EAPEGWGPTPRAG 249
>gi|4507565 tumor necrosis factor receptor superfamily, member 11a
precursor [Homo sapiens]
Length = 616
Score = 109 bits (273), Expect = 4e-24
Identities = 73/230 (31%), Positives = 106/230 (46%), Gaps = 18/230 (7%)
Query: 18 VLGLFGLLAASQP--QAVPPYASENQTCRDQEKEYYEPQHRICCSRCPPGTYVSAKCSRI 75
+L L LLA Q Q PP SE ++YE R CC++C PG Y+S+KC+
Sbjct: 14 LLLLCALLARLQVALQIAPPCTSE---------KHYEHLGR-CCNKCEPGKYMSSKCTTT 63
Query: 76 RDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKRKTQCRCQPGMFCAAW 135
D+VC C + Y + WN C L + CD L + S +C C G W
Sbjct: 64 SDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYH---W 120
Query: 136 ALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSSPSARCQPHTRCENQG 195
+ +C C ++C PG A+ ++ K + C PC AG+F + S + +C+P T C G
Sbjct: 121 SQDCECCRRNTECAPGLGAQHPLQLNK-DTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLG 179
Query: 196 LVEAAPGTAQSDTTCKN--PLEPLPPEMSGTMLMLAVLLPLAFFLLLATV 243
GT +SD C + P P E + L +LL A L+A +
Sbjct: 180 KRVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAI 229
>gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]
Length = 203
Score = 99.0 bits (245), Expect = 8e-21
Identities = 67/192 (34%), Positives = 89/192 (46%), Gaps = 24/192 (12%)
Query: 16 PLVLGLFG-LLAASQPQAVPPYASENQTCRDQEKEYYEPQHRICCSRCPPGTYVSAKCSR 74
PL L+G LL A P+ PP A CR EK+Y CCS C PG + + C+
Sbjct: 5 PLQCVLWGCLLTAVHPE--PPTA-----CR--EKQYLINSQ--CCSLCQPGQKLVSDCTE 53
Query: 75 IRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKRKTQCRCQPGMFCAA 134
+T C C E+ + + WN T C + CDP +GL TS+ T C C+ G C +
Sbjct: 54 FTETECLPCGESEFLDTWNRETHCHQHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCTS 113
Query: 135 WALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSSPSARCQPHTRCENQ 194
A C C L C PG + + G + C PC G F N SS +C P TR
Sbjct: 114 EA--CESCVLHRSCSPGFGVK-QIATGVSDTICEPCPVGFFSNVSSAFEKCHPWTR---- 166
Query: 195 GLVEAAPGTAQS 206
+PG+A+S
Sbjct: 167 -----SPGSAES 173
>gi|148743793 osteoprotegerin precursor [Homo sapiens]
Length = 401
Score = 93.6 bits (231), Expect = 3e-19
Identities = 51/165 (30%), Positives = 72/165 (43%), Gaps = 9/165 (5%)
Query: 52 EPQHRICCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRP-CDPVMGL 110
E H++ C +CPPGTY+ C+ TVCA C ++ Y + W+ C C P C + +
Sbjct: 34 ETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDHYYTDSWHTSDECLYCSPVCKELQYV 93
Query: 111 EEIAPCTSKRKTQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPC 170
++ C C C+ G + LE C CPPG ++ + N C C
Sbjct: 94 KQ--ECNRTHNRVCECKEGRY-----LEIEFCLKHRSCPPGF-GVVQAGTPERNTVCKRC 145
Query: 171 KAGHFQNTSSPSARCQPHTRCENQGLVEAAPGTAQSDTTCKNPLE 215
G F N +S A C+ HT C GL+ G A D C E
Sbjct: 146 PDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNATHDNICSGNSE 190
Score = 33.1 bits (74), Expect = 0.51
Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 1/73 (1%)
Query: 38 SENQTCRDQEKEYYEPQHRICCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTI 97
+ N+ C +E Y E + + CPPG V + R+TVC C + ++ +
Sbjct: 100 THNRVCECKEGRYLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAP 159
Query: 98 CQLCRPCDPVMGL 110
C+ C V GL
Sbjct: 160 CRKHTNCS-VFGL 171
>gi|23200041 tumor necrosis factor receptor superfamily, member 14
precursor [Homo sapiens]
Length = 283
Score = 89.0 bits (219), Expect = 8e-18
Identities = 64/251 (25%), Positives = 102/251 (40%), Gaps = 25/251 (9%)
Query: 34 PPYASENQTCRDQEKEYYEPQHRICCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWN 93
P YA +C++ E P CC +C PG V C + TVC C +Y H N
Sbjct: 33 PCYAPALPSCKEDEY----PVGSECCPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLN 88
Query: 94 YLTICQLCRPCDPVMGLEEIAPCTSKRKTQCRCQPGMFCAAW-ALECTHCELLSDCPPGT 152
L+ C C+ CDP MGL C+ C C PG FC C C + PG
Sbjct: 89 GLSKCLQCQMCDPAMGLRASRNCSRTENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQ 148
Query: 153 EAELKDEVGKGNNHCVPCKAGHFQNTSSPSARCQPHTRCENQGLVEAAPGTAQSDTTCKN 212
+ K + C C G F + + CQ T+C + + +A GT+ S
Sbjct: 149 RVQ-KGGTESQDTLCQNCPPGTF-SPNGTLEECQHQTKC-SWLVTKAGAGTSSSHWVWW- 204
Query: 213 PLEPLPPEMSGTMLMLAVLLPLAFFLLLATVFSCIWKSHP--SLCRKLGSLLKRRPQGEG 270
+SG+++++ V + + C+ + P + + + S+ ++R + EG
Sbjct: 205 -------FLSGSLVIVIVCSTVGLII-------CVKRRKPRGDVVKVIVSVQRKRQEAEG 250
Query: 271 PNPVAGSWEPP 281
V + + P
Sbjct: 251 EATVIEALQAP 261
>gi|7657039 tumor necrosis factor receptor superfamily, member 21
precursor [Homo sapiens]
Length = 655
Score = 85.9 bits (211), Expect = 7e-17
Identities = 49/155 (31%), Positives = 74/155 (47%), Gaps = 9/155 (5%)
Query: 57 ICCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLC-RPCDPVMGLEEIAP 115
+ C +CP GTYVS C+ VC++C ++ H N + C C +PC P +E++ P
Sbjct: 65 LTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPC-PWPMIEKL-P 122
Query: 116 CTSKRKTQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHF 175
C + +C C PGMF + C + CP G K + + C C G F
Sbjct: 123 CAALTDRECTCPPGMFQSN-----ATCAPHTVCPVGWGVRKKGTETE-DVRCKQCARGTF 176
Query: 176 QNTSSPSARCQPHTRCENQGLVEAAPGTAQSDTTC 210
+ S +C+ +T C +Q LV PGT ++D C
Sbjct: 177 SDVPSSVMKCKAYTDCLSQNLVVIKPGTKETDNVC 211
>gi|4507575 tumor necrosis factor receptor 1 precursor [Homo
sapiens]
Length = 455
Score = 80.1 bits (196), Expect = 4e-15
Identities = 81/271 (29%), Positives = 108/271 (39%), Gaps = 41/271 (15%)
Query: 17 LVLGLFGLLAASQPQAV---PPYASENQTCRDQ---EKEYYEPQHR-ICCSRCPPGTYVS 69
L L L LL P V P+ + + RD + +Y PQ+ ICC++C GTY+
Sbjct: 11 LPLVLLELLVGIYPSGVIGLVPHLGDREK-RDSVCPQGKYIHPQNNSICCTKCHKGTYLY 69
Query: 70 AKCSRI-RDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKRKTQCRCQP 128
C +DT C C S+ N+L C C C MG EI+ CT R T C C+
Sbjct: 70 NDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTVCGCRK 129
Query: 129 GMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHF--QNTSSPSARCQ 186
+ W+ C S C GT E K N C C AG F +N + C+
Sbjct: 130 NQYRHYWSENLFQCFNCSLCLNGTVHLSCQE--KQNTVCT-CHAGFFLRENECVSCSNCK 186
Query: 187 PHTRCENQGL--VEAAPGTAQSDTTCKNPLEPLPPEMSGTMLMLAVLLPLAFFL---LLA 241
C L +E GT S TT VLLPL F LL+
Sbjct: 187 KSLECTKLCLPQIENVKGTEDSGTT--------------------VLLPLVIFFGLCLLS 226
Query: 242 TVFSCIWKSHPSLCRKLGSLL--KRRPQGEG 270
+F + + KL S++ K P+ EG
Sbjct: 227 LLFIGLMYRYQRWKSKLYSIVCGKSTPEKEG 257
>gi|68348711 tumor necrosis factor receptor superfamily, member 8
isoform 1 precursor [Homo sapiens]
Length = 595
Score = 79.3 bits (194), Expect = 6e-15
Identities = 59/203 (29%), Positives = 79/203 (38%), Gaps = 13/203 (6%)
Query: 17 LVLGLFGLLAASQPQAVPPYASENQTCRDQEKEYYEPQHRICCSRCPPGTYVSAKCSRIR 76
++L GLL +A P TC YY+ R CC RCP G + + +C + R
Sbjct: 3 VLLAALGLLFLGALRAFPQDRPFEDTCHGNPSHYYDKAVRRCCYRCPMGLFPTQQCPQ-R 61
Query: 77 DTVC-ATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKRKTQCRCQPGMFCAAW 135
T C C + Y + + T C C D L E PC C C+PGMFC+
Sbjct: 62 PTDCRKQCEPDYYLDEADRCTACVTCSRDD----LVEKTPCAWNSSRVCECRPGMFCSTS 117
Query: 136 AL-ECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSSPSARCQPHTRCENQ 194
A+ C C S CP G + K N C P G +SP +P +
Sbjct: 118 AVNSCARCFFHSVCPAGMIVKFPGTAQK-NTVCEPASPGVSPACASPENCKEP-----SS 171
Query: 195 GLVEAAPGTAQSDTTCKNPLEPL 217
G + A T S T P+
Sbjct: 172 GTIPQAKPTPVSPATSSASTMPV 194
Score = 37.7 bits (86), Expect = 0.021
Identities = 79/361 (21%), Positives = 110/361 (30%), Gaps = 47/361 (13%)
Query: 64 PGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKRKTQ 123
PG + C C + Y + T C C D L E PC
Sbjct: 225 PGLSPTQPCPEGSGDCRKQCEPDYYLDEAGRCTACVSCSRDD----LVEKTPCAWNSSRT 280
Query: 124 CRCQPGMFCAAWALEC-THCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSSPS 182
C C+PGM CA A C C T + +D K P +P
Sbjct: 281 CECRPGMICATSATNSRARCVPYPICAAETVTKPQDMAEKDTTFEAPPLGTQPDCNPTPE 340
Query: 183 ARCQPHTRCENQGLVEAAPGTAQSDTTCKNPLEPLPPEMSGTMLMLAVLLPLAFFLLLAT 242
P + Q L+ +Q+ T P P +S T + P+ F+++L
Sbjct: 341 NGEAPASTSPTQSLLV----DSQASKTLPIPTS-APVALSSTGKPVLDAGPVLFWVILVL 395
Query: 243 VF----SCIWKSHPSLCRK-----------------LGSLLKRRPQGEGPNPVAGSWEPP 281
V S H CRK L+ RP+ +G+
Sbjct: 396 VVVVGSSAFLLCHRRACRKRIRQKLHLCYPVQTSQPKLELVDSRPRRSSTQLRSGASVTE 455
Query: 282 KAHPYFPDLVQPLLPISGDVSPVSTGLPAAPVLEAGVPQQQSPLDLTREPQLEPGEQSQV 341
+ QPL+ V A LE+ Q SP P+ P +
Sbjct: 456 PVAEERGLMSQPLMETCHSV--------GAAYLESLPLQDASPAGGPSSPRDLPEPRVST 507
Query: 342 AHGTN---GIHVTGGSMTITGNI--YIYNGPVLGGPPGP---GDLPATPEPPYPIPEEGD 393
H N I++ I G + + G L GP P +L A P YP E
Sbjct: 508 EHTNNKIEKIYIMKADTVIVGTVKAELPEGRGLAGPAEPELEEELEADHTPHYPEQETEP 567
Query: 394 P 394
P
Sbjct: 568 P 568
>gi|4507579 tumor necrosis factor receptor superfamily, member 4
precursor [Homo sapiens]
Length = 277
Score = 74.3 bits (181), Expect = 2e-13
Identities = 49/173 (28%), Positives = 70/173 (40%), Gaps = 30/173 (17%)
Query: 53 PQHRICCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEE 112
P + CC C PG + ++CSR ++TVC C YN+ + C+ C C+ G E
Sbjct: 37 PSNDRCCHECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKP-CKPCTWCNLRSGSER 95
Query: 113 IAPCTSKRKTQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKA 172
CT+ + T CRC+ G + L PG + C PC
Sbjct: 96 KQLCTATQDTVCRCRAG------------TQPLDSYKPGVD-------------CAPCPP 130
Query: 173 GHFQNTSSPSARCQPHTRCENQGLVEAAPGTAQSDTTC--KNPLEPLPPEMSG 223
GHF + + C+P T C G P + SD C ++P P E G
Sbjct: 131 GHF--SPGDNQACKPWTNCTLAGKHTLQPASNSSDAICEDRDPPATQPQETQG 181
>gi|5730095 tumor necrosis factor receptor superfamily, member 9
precursor [Homo sapiens]
Length = 255
Score = 72.0 bits (175), Expect = 1e-12
Identities = 49/164 (29%), Positives = 65/164 (39%), Gaps = 25/164 (15%)
Query: 59 CSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTS 118
CS CP GT+ C R+ +C+ C NS++ T C +CR C V + C+S
Sbjct: 28 CSNCPAGTF----CDNNRNQICSPCPPNSFSSAGGQRT-CDICRQCKGVFRTRK--ECSS 80
Query: 119 KRKTQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNT 178
+C C PG C C+ CE DC G E K C C G F +
Sbjct: 81 TSNAECDCTPGFHCLGAG--CSMCE--QDCKQGQELTKKG--------CKDCCFGTFNDQ 128
Query: 179 SSPSARCQPHTRCENQGLVEAAPGTAQSDTTCKNPLEPLPPEMS 222
C+P T C G GT + D C P P ++S
Sbjct: 129 KR--GICRPWTNCSLDGKSVLVNGTKERDVVC----GPSPADLS 166
>gi|23510421 tumor necrosis factor receptor superfamily, member 6
isoform 2 precursor [Homo sapiens]
Length = 314
Score = 68.9 bits (167), Expect = 8e-12
Identities = 51/166 (30%), Positives = 71/166 (42%), Gaps = 25/166 (15%)
Query: 42 TCRDQEKEYYEPQHRICCSRCPPGTYVSAKCSRIRDTV-CATCAENS-YNEHWNYLTICQ 99
T Q E + C CPPG + C+ D C C E Y + ++ + C+
Sbjct: 43 TVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCR 102
Query: 100 LCRPCDPVMGLEEIAPCTSKRKTQCRCQPGMFCAAWALE----CTHCE--LLSDCPPGTE 153
CR CD GLE CT + T+CRC+P FC + E CT CE ++ +C +
Sbjct: 103 RCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSN 162
Query: 154 AELKDEVGKGNNHCVPCKAGHFQNTSSPSARCQPHTRCENQGLVEA 199
+ K+EV K Q T C+ H R ENQG E+
Sbjct: 163 TKCKEEV----------KRKEVQKT------CRKH-RKENQGSHES 191
>gi|23510423 tumor necrosis factor receptor superfamily, member 6
isoform 3 precursor [Homo sapiens]
Length = 220
Score = 68.2 bits (165), Expect = 1e-11
Identities = 40/131 (30%), Positives = 59/131 (45%), Gaps = 8/131 (6%)
Query: 42 TCRDQEKEYYEPQHRICCSRCPPGTYVSAKCSRIRDTV-CATCAENS-YNEHWNYLTICQ 99
T Q E + C CPPG + C+ D C C E Y + ++ + C+
Sbjct: 43 TVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCR 102
Query: 100 LCRPCDPVMGLEEIAPCTSKRKTQCRCQPGMFCAAWALE----CTHCE--LLSDCPPGTE 153
CR CD GLE CT + T+CRC+P FC + E CT CE ++ +C +
Sbjct: 103 RCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSN 162
Query: 154 AELKDEVGKGN 164
+ K+E + N
Sbjct: 163 TKCKEEGSRSN 173
Score = 30.4 bits (67), Expect = 3.3
Identities = 19/66 (28%), Positives = 28/66 (42%), Gaps = 2/66 (3%)
Query: 148 CPPGTEAELKDEVGKGNNHCVPCKAG-HFQNTSSPSARCQPHTRC-ENQGLVEAAPGTAQ 205
CPPG V CVPC+ G + + + S++C+ C E GL T
Sbjct: 63 CPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCTRT 122
Query: 206 SDTTCK 211
+T C+
Sbjct: 123 QNTKCR 128
>gi|4507583 tumor necrosis factor receptor superfamily, member 6
isoform 1 precursor [Homo sapiens]
Length = 335
Score = 68.2 bits (165), Expect = 1e-11
Identities = 40/131 (30%), Positives = 59/131 (45%), Gaps = 8/131 (6%)
Query: 42 TCRDQEKEYYEPQHRICCSRCPPGTYVSAKCSRIRDTV-CATCAENS-YNEHWNYLTICQ 99
T Q E + C CPPG + C+ D C C E Y + ++ + C+
Sbjct: 43 TVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCR 102
Query: 100 LCRPCDPVMGLEEIAPCTSKRKTQCRCQPGMFCAAWALE----CTHCE--LLSDCPPGTE 153
CR CD GLE CT + T+CRC+P FC + E CT CE ++ +C +
Sbjct: 103 RCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSN 162
Query: 154 AELKDEVGKGN 164
+ K+E + N
Sbjct: 163 TKCKEEGSRSN 173
Score = 30.4 bits (67), Expect = 3.3
Identities = 19/66 (28%), Positives = 28/66 (42%), Gaps = 2/66 (3%)
Query: 148 CPPGTEAELKDEVGKGNNHCVPCKAG-HFQNTSSPSARCQPHTRC-ENQGLVEAAPGTAQ 205
CPPG V CVPC+ G + + + S++C+ C E GL T
Sbjct: 63 CPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCTRT 122
Query: 206 SDTTCK 211
+T C+
Sbjct: 123 QNTKCR 128
>gi|224494019 tumor necrosis factor receptor superfamily, member 10b
isoform 1 precursor [Homo sapiens]
Length = 440
Score = 62.0 bits (149), Expect = 1e-09
Identities = 56/193 (29%), Positives = 84/193 (43%), Gaps = 40/193 (20%)
Query: 62 CPPGTYVSAKCSRIRDTVCATCAENS-YNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKR 120
CPPG ++S RD C +C Y+ HWN L C C CD G E++PCT+ R
Sbjct: 81 CPPGHHISEDG---RD--CISCKYGQDYSTHWNDLLFCLRCTRCDS--GEVELSPCTTTR 133
Query: 121 KTQCRCQPGMFCAAWALE-CTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTS 179
T C+C+ G F + E C C + CP G ++ D + CV ++G +
Sbjct: 134 NTVCQCEEGTFREEDSPEMCRKCR--TGCPRGM-VKVGDCTPWSDIECVHKESGTKHSGE 190
Query: 180 SPSARCQPHTRCENQGLVEAAPGTAQSDTTCKNPLEPLPPEMSGTMLMLAVLLPLAFFLL 239
P+ + V ++PGT S P +SG ++ + V A +L
Sbjct: 191 VPAV----------EETVTSSPGTPAS-----------PCSLSGIIIGVTV----AAVVL 225
Query: 240 LATVFSC---IWK 249
+ VF C +WK
Sbjct: 226 IVAVFVCKSLLWK 238
Score = 36.6 bits (83), Expect = 0.046
Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 3/66 (4%)
Query: 59 CSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTS 118
C+RC G + C+ R+TVC C E ++ E + +C+ CR P G+ ++ CT
Sbjct: 116 CTRCDSGEVELSPCTTTRNTVC-QCEEGTFREE-DSPEMCRKCRTGCP-RGMVKVGDCTP 172
Query: 119 KRKTQC 124
+C
Sbjct: 173 WSDIEC 178
>gi|224494026 tumor necrosis factor receptor superfamily, member 10b
isoform 2 precursor [Homo sapiens]
Length = 411
Score = 57.0 bits (136), Expect = 3e-08
Identities = 35/92 (38%), Positives = 46/92 (50%), Gaps = 11/92 (11%)
Query: 62 CPPGTYVSAKCSRIRDTVCATCAENS-YNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKR 120
CPPG ++S RD C +C Y+ HWN L C C CD G E++PCT+ R
Sbjct: 81 CPPGHHISEDG---RD--CISCKYGQDYSTHWNDLLFCLRCTRCDS--GEVELSPCTTTR 133
Query: 121 KTQCRCQPGMFCAAWALE-CTHCELLSDCPPG 151
T C+C+ G F + E C C + CP G
Sbjct: 134 NTVCQCEEGTFREEDSPEMCRKCR--TGCPRG 163
Score = 36.6 bits (83), Expect = 0.046
Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 3/66 (4%)
Query: 59 CSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTS 118
C+RC G + C+ R+TVC C E ++ E + +C+ CR P G+ ++ CT
Sbjct: 116 CTRCDSGEVELSPCTTTRNTVC-QCEEGTFREE-DSPEMCRKCRTGCP-RGMVKVGDCTP 172
Query: 119 KRKTQC 124
+C
Sbjct: 173 WSDIEC 178
>gi|4507587 tumor necrosis factor receptor superfamily, member 7
precursor [Homo sapiens]
Length = 260
Score = 53.9 bits (128), Expect = 3e-07
Identities = 38/135 (28%), Positives = 57/135 (42%), Gaps = 21/135 (15%)
Query: 14 WGPLVLG-LFGLLAASQPQAVPPYASENQTCRDQEKEYYEPQHRICCSRCPPGTYVSAKC 72
W VLG L GL A P++ P + +Y Q ++CC C PGT++ C
Sbjct: 7 WWLCVLGTLVGLSATPAPKSCP-------------ERHYWAQGKLCCQMCEPGTFLVKDC 53
Query: 73 SRIRDTV-CATCAEN-SYNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKRKTQCRCQPGM 130
+ R C C S++ + C+ CR C+ + + CT +C C+ G
Sbjct: 54 DQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCNSGL---LVRNCTITANAECACRNGW 110
Query: 131 FCAAWALECTHCELL 145
C ECT C+ L
Sbjct: 111 QCR--DKECTECDPL 123
>gi|4505393 nerve growth factor receptor precursor [Homo sapiens]
Length = 427
Score = 53.5 bits (127), Expect = 4e-07
Identities = 36/137 (26%), Positives = 56/137 (40%), Gaps = 8/137 (5%)
Query: 58 CCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEI-APC 116
CC C G V+ C TVC C ++ + ++ + C+PC +GL+ + APC
Sbjct: 43 CCKACNLGEGVAQPCGA-NQTVCEPCLDSVTFS--DVVSATEPCKPCTECVGLQSMSAPC 99
Query: 117 TSKRKTQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQ 176
CRC G + C C + C G+ + K N C C G +
Sbjct: 100 VEADDAVCRCAYGYYQDETTGRCEACRV---CEAGSGLVFSCQ-DKQNTVCEECPDGTYS 155
Query: 177 NTSSPSARCQPHTRCEN 193
+ ++ C P T CE+
Sbjct: 156 DEANHVDPCLPCTVCED 172
>gi|23200023 tumor necrosis factor receptor superfamily, member 25
isoform 3 precursor [Homo sapiens]
Length = 380
Score = 53.5 bits (127), Expect = 4e-07
Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 11/100 (11%)
Query: 58 CCSRCPPGTYVSAKCSR-IRDTVCATCAENSY---NEHWNYLTICQLCRPCDPVMGLEEI 113
CC CP G Y+ A C+ ++ C C ++++ H N + C C+ CD +
Sbjct: 47 CCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHN--SECARCQACDEQASQVAL 104
Query: 114 APCTSKRKTQCRCQPGMFCAAWALECT-----HCELLSDC 148
C++ T+C C+PG F +C +C+ DC
Sbjct: 105 ENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDC 144
>gi|23200021 tumor necrosis factor receptor superfamily, member 25
isoform 1 precursor [Homo sapiens]
Length = 426
Score = 53.5 bits (127), Expect = 4e-07
Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 11/100 (11%)
Query: 58 CCSRCPPGTYVSAKCSR-IRDTVCATCAENSY---NEHWNYLTICQLCRPCDPVMGLEEI 113
CC CP G Y+ A C+ ++ C C ++++ H N + C C+ CD +
Sbjct: 47 CCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHN--SECARCQACDEQASQVAL 104
Query: 114 APCTSKRKTQCRCQPGMFCAAWALECT-----HCELLSDC 148
C++ T+C C+PG F +C +C+ DC
Sbjct: 105 ENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDC 144
>gi|89142745 tumor necrosis factor receptor superfamily, member 25
isoform 12 precursor [Homo sapiens]
Length = 181
Score = 53.5 bits (127), Expect = 4e-07
Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 11/100 (11%)
Query: 58 CCSRCPPGTYVSAKCSR-IRDTVCATCAENSY---NEHWNYLTICQLCRPCDPVMGLEEI 113
CC CP G Y+ A C+ ++ C C ++++ H N + C C+ CD +
Sbjct: 47 CCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHN--SECARCQACDEQASQVAL 104
Query: 114 APCTSKRKTQCRCQPGMFCAAWALECT-----HCELLSDC 148
C++ T+C C+PG F +C +C+ DC
Sbjct: 105 ENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDC 144
>gi|4507569 tumor necrosis factor receptor superfamily, member 25
isoform 2 precursor [Homo sapiens]
Length = 417
Score = 53.5 bits (127), Expect = 4e-07
Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 11/100 (11%)
Query: 58 CCSRCPPGTYVSAKCSR-IRDTVCATCAENSY---NEHWNYLTICQLCRPCDPVMGLEEI 113
CC CP G Y+ A C+ ++ C C ++++ H N + C C+ CD +
Sbjct: 47 CCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHN--SECARCQACDEQASQVAL 104
Query: 114 APCTSKRKTQCRCQPGMFCAAWALECT-----HCELLSDC 148
C++ T+C C+PG F +C +C+ DC
Sbjct: 105 ENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDC 144
>gi|21361086 tumor necrosis factor receptor superfamily, member 10a
[Homo sapiens]
Length = 468
Score = 51.6 bits (122), Expect = 1e-06
Identities = 42/144 (29%), Positives = 58/144 (40%), Gaps = 18/144 (12%)
Query: 33 VPPYASENQTCRDQEKEYYEPQHRICCSRCPPGTYVSAKCSRIRDTVCATCAEN-SYNEH 91
V P ++ DQ + +H CPPG++ S C C E Y
Sbjct: 103 VVPSSAATIKLHDQSIGTQQWEHSPLGELCPPGSHRSE-----HPGACNRCTEGVGYTNA 157
Query: 92 WNYLTICQLCRPCDPVMGLEEIAPCTSKRKTQCRCQPGMFCAAWALE-CTHCE------- 143
N L C C C EE +PCT+ R T C+C+PG F + E C C
Sbjct: 158 SNNLFACLPCTACKS--DEEERSPCTTTRNTACQCKPGTFRNDNSAEMCRKCSRGCPRGM 215
Query: 144 -LLSDCPPGTEAE-LKDEVGKGNN 165
+ DC P ++ E + E G G+N
Sbjct: 216 VKVKDCTPWSDIECVHKESGNGHN 239
>gi|23238200 RELT tumor necrosis factor receptor precursor [Homo
sapiens]
Length = 430
Score = 48.9 bits (115), Expect = 9e-06
Identities = 30/76 (39%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 135 WALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSSPSARCQPHTRCENQ 194
W L L CPPG E +L + G+G C PC G F + + S+ CQPH RC
Sbjct: 19 WPLATLTSTTLWQCPPGEEPDL--DPGQGTL-CRPCPPGTF-SAAWGSSPCQPHARCSLW 74
Query: 195 GLVEAAPGTAQSDTTC 210
+EA G A DT C
Sbjct: 75 RRLEAQVGMATRDTLC 90
Score = 31.6 bits (70), Expect = 1.5
Identities = 36/132 (27%), Positives = 48/132 (36%), Gaps = 27/132 (20%)
Query: 43 CRDQEKEYYEPQHRICCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCR 102
C E+ +P C CPPGT+ +A S + C A C L R
Sbjct: 32 CPPGEEPDLDPGQGTLCRPCPPGTFSAAWGS----SPCQPHAR------------CSLWR 75
Query: 103 PCDPVMGLEEIAPCTSKRKTQC-RCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVG 161
+ +G+ + R T C C PG F W + C+ S P GT DE G
Sbjct: 76 RLEAQVGM-------ATRDTLCGDCWPGWF-GPWGVPRVPCQPCSWAPLGTHG--CDEWG 125
Query: 162 KGNNHCVPCKAG 173
+ V AG
Sbjct: 126 RRARRGVEVAAG 137
>gi|21361873 RELT tumor necrosis factor receptor precursor [Homo
sapiens]
Length = 430
Score = 48.9 bits (115), Expect = 9e-06
Identities = 30/76 (39%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 135 WALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSSPSARCQPHTRCENQ 194
W L L CPPG E +L + G+G C PC G F + + S+ CQPH RC
Sbjct: 19 WPLATLTSTTLWQCPPGEEPDL--DPGQGTL-CRPCPPGTF-SAAWGSSPCQPHARCSLW 74
Query: 195 GLVEAAPGTAQSDTTC 210
+EA G A DT C
Sbjct: 75 RRLEAQVGMATRDTLC 90
Score = 31.6 bits (70), Expect = 1.5
Identities = 36/132 (27%), Positives = 48/132 (36%), Gaps = 27/132 (20%)
Query: 43 CRDQEKEYYEPQHRICCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCR 102
C E+ +P C CPPGT+ +A S + C A C L R
Sbjct: 32 CPPGEEPDLDPGQGTLCRPCPPGTFSAAWGS----SPCQPHAR------------CSLWR 75
Query: 103 PCDPVMGLEEIAPCTSKRKTQC-RCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVG 161
+ +G+ + R T C C PG F W + C+ S P GT DE G
Sbjct: 76 RLEAQVGM-------ATRDTLCGDCWPGWF-GPWGVPRVPCQPCSWAPLGTHG--CDEWG 125
Query: 162 KGNNHCVPCKAG 173
+ V AG
Sbjct: 126 RRARRGVEVAAG 137
>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein
[Homo sapiens]
Length = 1629
Score = 47.4 bits (111), Expect = 3e-05
Identities = 33/101 (32%), Positives = 41/101 (40%), Gaps = 14/101 (13%)
Query: 319 PQQQSPLDLTREPQLEPGE---------QSQVAHGTNGIHVTGGSMTITGNIYIYNGPVL 369
PQ Q P R PQ +P QSQ AHG G+ G + + GP
Sbjct: 236 PQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPP- 294
Query: 370 GGPPGPGDL---PATPEPPYPIPEEGDPGPPGLSTPHQEDG 407
GP GP L P P P+ + G+ GPPG + DG
Sbjct: 295 -GPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDG 334
Score = 38.9 bits (89), Expect = 0.009
Identities = 31/98 (31%), Positives = 36/98 (36%), Gaps = 2/98 (2%)
Query: 334 EPGEQ-SQVAHGTNGIHVTGGSMTITGNIYIYNGPVLGGPPGPGDLPATPEPPYPIPEEG 392
EPGE S G G+ G G P GP GP P P+ G
Sbjct: 1107 EPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPG 1166
Query: 393 DPGPPGLSTPHQEDGKAWHLAETEHCGATPSNRGPRNQ 430
DPGPPG P +DG E G P + GP +
Sbjct: 1167 DPGPPGEGGPRGQDGAKGDRGEDGEPG-QPGSPGPTGE 1203
Score = 33.9 bits (76), Expect = 0.30
Identities = 24/64 (37%), Positives = 28/64 (43%), Gaps = 5/64 (7%)
Query: 335 PGEQSQVAHGTNGIHVTGGSMTITGNIYIYNGPVLGGPPGPGDLPATPEPPYPIPEEGDP 394
PGEQ + G G+ GS G + I P GP GPG P P P P +G
Sbjct: 1315 PGEQGE--KGDRGLPGPQGSPGQKGEMGI---PGASGPIGPGGPPGLPGPAGPKGAKGAT 1369
Query: 395 GPPG 398
GP G
Sbjct: 1370 GPGG 1373
Score = 32.7 bits (73), Expect = 0.66
Identities = 30/97 (30%), Positives = 39/97 (40%), Gaps = 3/97 (3%)
Query: 307 GLPAAPVLEAGVPQQQSPLDLTREPQLEPGEQSQVAH-GTNGIHVTGGSMTITGNIYIYN 365
G+P P + G+ Q P + PQ EPG Q GT G+ G++ G
Sbjct: 512 GIPGPPGVR-GMDGPQGPKG-SLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQG 569
Query: 366 GPVLGGPPGPGDLPATPEPPYPIPEEGDPGPPGLSTP 402
P L G PG P P P +G+ GP G P
Sbjct: 570 KPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGP 606
Score = 32.3 bits (72), Expect = 0.86
Identities = 25/82 (30%), Positives = 30/82 (36%), Gaps = 6/82 (7%)
Query: 344 GTNGIHVTGGSMTITGNIYIYNGPVLGGPPGPGDLPATPEPPYPIPE------EGDPGPP 397
G +G H G + G P GPPGP P P E G PGPP
Sbjct: 758 GGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPP 817
Query: 398 GLSTPHQEDGKAWHLAETEHCG 419
G+ P G+ + E H G
Sbjct: 818 GVVGPQGAAGETGPMGERGHPG 839
Score = 32.0 bits (71), Expect = 1.1
Identities = 47/158 (29%), Positives = 50/158 (31%), Gaps = 27/158 (17%)
Query: 266 PQGEGPNPVAGSWEPP--------KAHPY------FPDLVQPLLPISGDVSPVSTGLPAA 311
P +GPN G PP HP F P P G V P
Sbjct: 772 PGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP-PGVVGPQGAAGETG 830
Query: 312 PVLEAGVPQQQSPLDLTREPQLEPGEQSQVAHGTNGIHVTGGSMTITGNIYIYNGPVLGG 371
P+ E G P P PGEQ GT G T G G L G
Sbjct: 831 PMGERGHPGPPGP----------PGEQG--LPGTAGKEGTKGDPGPPGAPGKDGPAGLRG 878
Query: 372 PPGPGDLPATPEPPYPIPEEGDPGPPGLSTPHQEDGKA 409
PG LP T P EG GPPG + E G A
Sbjct: 879 FPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAA 916
Score = 32.0 bits (71), Expect = 1.1
Identities = 44/171 (25%), Positives = 51/171 (29%), Gaps = 26/171 (15%)
Query: 251 HPSLCRKLGSLLKRRPQGE----GPNPVAGSWEP--PKAHPYFPDLVQPLLPISGDVSPV 304
HP ++G K P G GP AG P + HP P P
Sbjct: 798 HPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPG------------PPG 845
Query: 305 STGLPAAPVLEA--------GVPQQQSPLDLTREPQLEPGEQSQVAHGTNGIHVTGGSMT 356
GLP E G P + P L P + G G G
Sbjct: 846 EQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPG 905
Query: 357 ITGNIYIYNGPVLGGPPGPGDLPATPEPPYPIPEEGDPGPPGLSTPHQEDG 407
G+ GGP GP P PP E+G PG G P DG
Sbjct: 906 PAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDG 956
Score = 32.0 bits (71), Expect = 1.1
Identities = 28/99 (28%), Positives = 32/99 (32%), Gaps = 15/99 (15%)
Query: 315 EAGVPQQQSPLDLTREPQLEPGEQSQVAHGTNGIHVTGGSMTITGNIYIYNGPVLGGPPG 374
E G P P+ +P + A G G G G GPPG
Sbjct: 996 EHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRG---------FNGPPG 1046
Query: 375 PGDLPATPEPPYPIPEEGD------PGPPGLSTPHQEDG 407
P L P P E GD PGPPG P +G
Sbjct: 1047 PIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNG 1085
Score = 31.2 bits (69), Expect = 1.9
Identities = 41/157 (26%), Positives = 49/157 (31%), Gaps = 42/157 (26%)
Query: 297 ISGDVSPVSTGLPAAPVLEAGVPQQQSPLDLTREPQLEPGEQSQV-AHGTNGIHVTGGSM 355
+ G+ P PA E G P+ P PG Q A G G+ G +
Sbjct: 894 LKGNEGPSGPPGPAGSPGERGAAGSGGPIG----PPGRPGPQGPPGAAGEKGVPGEKGPI 949
Query: 356 TITGNIYIYNGPVLGGPPGPGDLPATPEPPYPIPEEGD---------------------P 394
TG G GP LP PP E+GD P
Sbjct: 950 GPTGR---------DGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPP 1000
Query: 395 GPPGLSTPHQEDGKAWHLAETEHCGATPSNRGPRNQF 431
GPPG P + G A E P RGP+ F
Sbjct: 1001 GPPGPIGPVGQPGAAGADGE-------PGARGPQGHF 1030
Score = 31.2 bits (69), Expect = 1.9
Identities = 46/163 (28%), Positives = 56/163 (34%), Gaps = 18/163 (11%)
Query: 266 PQGE-GPNPVAGSWEPPKAHPYFPDLVQPLLPISGDVSPVSTGLPAAPVLEAGVPQQQSP 324
P+G GPN G PP V L P P +G P G P + P
Sbjct: 1077 PRGPAGPNGADGPQGPPGG-------VGNLGPPGEKGEPGESGSPGIQ----GEPGVKGP 1125
Query: 325 LDLTREPQLEPGEQSQVAH-GTNGIHVTGGSMTITGNIYIYNGPVLGGPPGPGDLPATPE 383
R + E GE Q G G G GN P GPPG G
Sbjct: 1126 ----RGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDG 1181
Query: 384 PPYPIPEEGDPGPPGLSTPHQEDGKAWHLAETEHCGATPSNRG 426
E+G+PG PG P E+G L + G +P + G
Sbjct: 1182 AKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAG-SPGSEG 1223
Score = 30.0 bits (66), Expect = 4.3
Identities = 34/117 (29%), Positives = 43/117 (36%), Gaps = 16/117 (13%)
Query: 317 GVPQQQSPLDLTREPQLEPGEQSQVAHGTNGIHVTGGSMTITGNIYIYNGPVLGGPPGPG 376
G+P + P L P+ PG G G+ G G++ P GPPG
Sbjct: 494 GLPGESGPRGLLG-PKGPPG-----IPGPPGVRGMDGPQGPKGSLGPQGEP---GPPGQQ 544
Query: 377 DLPATPEPPYPIP------EEGDPGPPGLSTPHQEDGKAWHLAETEHCGATPSNRGP 427
P T P P E+G G PGL DG H + E T N+GP
Sbjct: 545 GTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGK-EGPPGTKGNQGP 600
Score = 29.3 bits (64), Expect = 7.3
Identities = 24/87 (27%), Positives = 30/87 (34%), Gaps = 7/87 (8%)
Query: 344 GTNGIHVTGGSMTITGNIYIYNGPVLGGPPGPGDLPATPEPPYPIPEEGDPGPPGLSTPH 403
G G+ G TG++ P GP GP P P G+ GPPG
Sbjct: 1049 GLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP 1108
Query: 404 QEDGKAWHLAETEHCGATPSNRGPRNQ 430
E G E P +GPR +
Sbjct: 1109 GESGSPGIQGE-------PGVKGPRGE 1128
>gi|122937440 multiple EGF-like-domains 9 [Homo sapiens]
Length = 639
Score = 46.2 bits (108), Expect = 6e-05
Identities = 36/110 (32%), Positives = 42/110 (38%), Gaps = 17/110 (15%)
Query: 80 CATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKRKTQC----------RCQPG 129
C TC E Y NY + LC+PCD PC S K QC RCQ G
Sbjct: 272 CETCKEGFY---LNYTS--GLCQPCDCSPHGALSIPCNSSGKCQCKVGVIGSICDRCQDG 326
Query: 130 M--FCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQN 177
F L C + C T A L + NHC CK G +Q+
Sbjct: 327 YYGFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGNHCEECKEGFYQS 376
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.136 0.452
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,141,611
Number of Sequences: 37866
Number of extensions: 1611191
Number of successful extensions: 14992
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 173
Number of HSP's successfully gapped in prelim test: 411
Number of HSP's that attempted gapping in prelim test: 8337
Number of HSP's gapped (non-prelim): 4489
length of query: 435
length of database: 18,247,518
effective HSP length: 105
effective length of query: 330
effective length of database: 14,271,588
effective search space: 4709624040
effective search space used: 4709624040
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.