BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|33598924 scavenger receptor class A, member 3 isoform 1 [Homo sapiens] (606 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|33598924 scavenger receptor class A, member 3 isoform 1 [Homo... 1229 0.0 gi|33598922 scavenger receptor class A, member 3 isoform 2 [Homo... 900 0.0 gi|18641360 collectin sub-family member 12 [Homo sapiens] 351 1e-96 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 159 9e-39 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 158 1e-38 gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] 157 2e-38 gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] 157 2e-38 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 157 3e-38 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 157 3e-38 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 157 3e-38 gi|119508426 alpha 3 type IX collagen [Homo sapiens] 157 3e-38 gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 156 5e-38 gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 156 5e-38 gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 156 5e-38 gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 156 6e-38 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 155 1e-37 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 155 1e-37 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 155 1e-37 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 155 1e-37 gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 154 3e-37 gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 154 3e-37 gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 154 3e-37 gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 154 3e-37 gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens] 154 3e-37 gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens] 153 4e-37 gi|48762934 alpha 2 type I collagen [Homo sapiens] 153 5e-37 gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] 152 7e-37 gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 152 9e-37 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 151 2e-36 gi|145701009 acetylcholinesterase collagen-like tail subunit iso... 150 2e-36 >gi|33598924 scavenger receptor class A, member 3 isoform 1 [Homo sapiens] Length = 606 Score = 1229 bits (3181), Expect = 0.0 Identities = 606/606 (100%), Positives = 606/606 (100%) Query: 1 MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKGRPGPRCSRCQKNLSLHTSVRILYL 60 MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKGRPGPRCSRCQKNLSLHTSVRILYL Sbjct: 1 MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKGRPGPRCSRCQKNLSLHTSVRILYL 60 Query: 61 FLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGLDPKALNNCSFCH 120 FLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGLDPKALNNCSFCH Sbjct: 61 FLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGLDPKALNNCSFCH 120 Query: 121 EAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQ 180 EAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQ Sbjct: 121 EAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQ 180 Query: 181 VNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRK 240 VNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRK Sbjct: 181 VNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRK 240 Query: 241 TDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDL 300 TDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDL Sbjct: 241 TDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDL 300 Query: 301 VLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTI 360 VLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTI Sbjct: 301 VLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTI 360 Query: 361 FTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLL 420 FTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLL Sbjct: 361 FTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLL 420 Query: 421 SARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGR 480 SARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGR Sbjct: 421 SARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGR 480 Query: 481 GPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPK 540 GPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPK Sbjct: 481 GPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPK 540 Query: 541 GDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPP 600 GDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPP Sbjct: 541 GDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPP 600 Query: 601 GSQSFY 606 GSQSFY Sbjct: 601 GSQSFY 606 >gi|33598922 scavenger receptor class A, member 3 isoform 2 [Homo sapiens] Length = 466 Score = 900 bits (2326), Expect = 0.0 Identities = 457/457 (100%), Positives = 457/457 (100%) Query: 1 MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKGRPGPRCSRCQKNLSLHTSVRILYL 60 MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKGRPGPRCSRCQKNLSLHTSVRILYL Sbjct: 1 MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKGRPGPRCSRCQKNLSLHTSVRILYL 60 Query: 61 FLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGLDPKALNNCSFCH 120 FLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGLDPKALNNCSFCH Sbjct: 61 FLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGLDPKALNNCSFCH 120 Query: 121 EAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQ 180 EAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQ Sbjct: 121 EAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQ 180 Query: 181 VNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRK 240 VNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRK Sbjct: 181 VNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRK 240 Query: 241 TDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDL 300 TDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDL Sbjct: 241 TDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDL 300 Query: 301 VLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTI 360 VLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTI Sbjct: 301 VLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTI 360 Query: 361 FTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLL 420 FTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLL Sbjct: 361 FTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLL 420 Query: 421 SARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRG 457 SARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRG Sbjct: 421 SARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRG 457 >gi|18641360 collectin sub-family member 12 [Homo sapiens] Length = 742 Score = 351 bits (901), Expect = 1e-96 Identities = 203/587 (34%), Positives = 324/587 (55%), Gaps = 2/587 (0%) Query: 18 EDLAGDDEDMPTFPCTQKG-RPGPRCSRCQKNLSLHTSVRILYLFLALLLVAVAVLASLV 76 +D ++E++ +F + G + G +C++C+ N +L S+ +LY+ ALL + VA+L V Sbjct: 2 KDDFAEEEEVQSFGYKRFGIQEGTQCTKCKNNWALKFSIILLYILCALLTITVAILGYKV 61 Query: 77 FRKVDSLSEDISLTQSIYDKKLVLMQKNLQGL-DPKALNNCSFCHEAGQLGPEIRKLQEE 135 K+D+++ + ++ YD KL ++ +L+ L D S E +I L+++ Sbjct: 62 VEKMDNVTGGMETSRQTYDDKLTAVESDLKKLGDQTGKKAISTNSELSTFRSDILDLRQQ 121 Query: 136 LEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQVNQSLGLFLAQVRGW 195 L I + + L++ + + L Q+ + + + SF I VN++L + V Sbjct: 122 LREITEKTSKNKDTLEKLQASGDALVDRQSQLKETLENNSFLITTVNKTLQAYNGYVTNL 181 Query: 196 QATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRKTDEETLTLQKIVTDW 255 Q T+ L +L++ V ++ +N T Q I +QR D+ + +Q+I D+ Sbjct: 182 QQDTSVLQGNLQNQMYSHNVVIMNLNNLNLTQVQQRNLITNLQRSVDDTSQAIQRIKNDF 241 Query: 256 QNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDLVLQVMGLQLQLDNIS 315 QN ++F + + E V+++Q +S N++++ D+ Q+ Q++NI+ Sbjct: 242 QNLQQVFLQAKKDTDWLKEKVQSLQTLAANNSALAKANNDTLEDMNSQLNSFTGQMENIT 301 Query: 316 SFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTIFTNINATDNHVHSML 375 + +E+N+ DLQ A+NRT +F LE R E +I I +NI+ T +H+ ++ Sbjct: 302 TISQANEQNLKDLQDLHKDAENRTAIKFNQLEERFQLFETDIVNIISNISYTAHHLRTLT 361 Query: 376 KYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLLSARLDLNVRNLSMIV 435 L++VR +CT H ++L LN +++ + + LR + L+ +RLD V NLS+I+ Sbjct: 362 SNLNEVRTTCTDTLTKHTDDLTSLNNTLANIRLDSVSLRMQQDLMRSRLDTEVANLSVIM 421 Query: 436 EEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQ 495 EEMK VD++HG++++N TIL+G PGP GPRG +G G GP G +G KG+ G GP GP Sbjct: 422 EEMKLVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPA 481 Query: 496 GPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP 555 G +G G AGP GERG G +G G KGS+GS G GP+G G G GPPG EG PG Sbjct: 482 GERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQ 541 Query: 556 GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 GP G QG G G+ G PG RG G G PG+ GP G PGPPGP G+ Sbjct: 542 GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588 Score = 43.1 bits (100), Expect = 7e-04 Identities = 25/53 (47%), Positives = 25/53 (47%), Gaps = 3/53 (5%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509 G PG PGPRG G GV G G PKG PG GP G P E P E Sbjct: 554 GEPGVPGPRGLPGLPGVPGMPG---PKGPPGPPGPSGAVVPLALQNEPTPAPE 603 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 159 bits (401), Expect = 9e-39 Identities = 81/164 (49%), Positives = 94/164 (57%), Gaps = 15/164 (9%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L+G PGPPG +G GD+G GP G GP+G G+ G GPQGP G G G VGE+G G Sbjct: 1229 LQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPG 1288 Query: 515 PRGFPGL---------KGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP------SG 559 G PGL KG +G G GP G GP G GPPG +GP GSPGP G Sbjct: 1289 EAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPG 1348 Query: 560 PQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 P G+PG AG+ G PG +G G G+ G GP G PGP GPPG + Sbjct: 1349 PPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKR 1392 Score = 158 bits (400), Expect = 1e-38 Identities = 84/167 (50%), Positives = 95/167 (56%), Gaps = 18/167 (10%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQ---PGEAGP----- 506 L+G GPPGP G G G +GP G GP G PG GP GP GP G+ PGE GP Sbjct: 1073 LKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAG 1132 Query: 507 -------VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP---EGPPGSPG 556 VG GP GP G PG G KG G G +G G KG+ GPPGP +GP G PG Sbjct: 1133 RDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPG 1192 Query: 557 PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 PSG G+PG G+ G GQ+G GP+G PG GP GL G PGPPG + Sbjct: 1193 PSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEK 1239 Score = 157 bits (397), Expect = 3e-38 Identities = 81/157 (51%), Positives = 89/157 (56%), Gaps = 12/157 (7%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP---- 512 G GPPG G KG++G G G +G KG+ G GP GPQGP GQPG +G GE GP Sbjct: 1147 GPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQ 1206 Query: 513 --------VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564 GPRGFPG G G G GP G+ G GD+G GP GPPG GPSG G Sbjct: 1207 GLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGAD 1266 Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G G G GA+G KGEPG G PGLPG GPPG Sbjct: 1267 GPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPG 1303 Score = 157 bits (396), Expect = 3e-38 Identities = 79/146 (54%), Positives = 88/146 (60%), Gaps = 3/146 (2%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG PGP GP G +G+ G KG G GP PG GP+GPQG G+PG G G GPVG Sbjct: 1392 RGPPGPAGPEGRQGEKGAKGEAGLEGP---PGKTGPIGPQGAPGKPGPDGLRGIPGPVGE 1448 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 +G PG G G G GP G PG KGD GP G +G PG G GP G+ G G G PG Sbjct: 1449 QGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP 1508 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPG 601 +G+ GPKGE GI GP G GPPGPPG Sbjct: 1509 QGSSGPKGEQGITGPSGPIGPPGPPG 1534 Score = 156 bits (395), Expect = 5e-38 Identities = 84/173 (48%), Positives = 95/173 (54%), Gaps = 24/173 (13%) Query: 450 RNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509 R T +G GPPGP G +G +GP G GP G+ G GP GP G QG PG AG G Sbjct: 981 RGETGFQGKTGPPGPPGV---VGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGT 1037 Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGP------KGDIGPPGPEGPPGSPGP------ 557 +G GP G PG G G G G RG PGP KG+ GPPGP GP GSPG Sbjct: 1038 KGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGA 1097 Query: 558 ---------SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 GPQG PG AG+ G+PG++G GP G G+QGP GLPGP GP G Sbjct: 1098 AGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVG 1150 Score = 155 bits (392), Expect = 1e-37 Identities = 81/153 (52%), Positives = 89/153 (58%), Gaps = 9/153 (5%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PGP G RG KG+ G G G GPKG PG GP G GP G PG+ GP GE GP G Sbjct: 1300 GPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQD 1359 Query: 517 GFPGLKGSKGS---FGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI---AGKT 570 G PG KG G G+ GP G+PGP G PPG GPPG GP G QG+ G AG Sbjct: 1360 GPPGDKGDDGEPGQTGSPGPTGEPGPSG---PPGKRGPPGPAGPEGRQGEKGAKGEAGLE 1416 Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G PG+ G +GP+G PG GP GL G PGP G Q Sbjct: 1417 GPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQ 1449 Score = 155 bits (391), Expect = 1e-37 Identities = 84/185 (45%), Positives = 93/185 (50%), Gaps = 36/185 (19%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGG------------RGPKGDPGSLGPLGPQGPQGQPG 502 L G GPPG RGF GD G+ GPVG GP G PG GP G GP G PG Sbjct: 1046 LPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPG 1105 Query: 503 EAGPVGERGPVGPRGFPGLKGSKGSFGTG---GPRGQPGPKGDIGPP------------- 546 GP G GP G +G PG KG +G G GP G PGP G +GPP Sbjct: 1106 RPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPG 1165 Query: 547 --------GPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPG 598 G +GPPG GP GP G+PG +G G PG RG G G+ G +GP G PGPPG Sbjct: 1166 QKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPG 1225 Query: 599 PPGSQ 603 P G Q Sbjct: 1226 PVGLQ 1230 Score = 150 bits (380), Expect = 2e-36 Identities = 82/165 (49%), Positives = 89/165 (53%), Gaps = 21/165 (12%) Query: 460 GPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP---R 516 GP GP G G G GP G G KG+PG +GP GP+G QG PG AG G RG G R Sbjct: 559 GPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGAR 618 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ- 575 G PG G KG G G G PG KG G PGP GPPG PG G +G G G G PG+ Sbjct: 619 GMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEP 678 Query: 576 --RGAMGPKGEPGIQGPPGL------PGP---------PGPPGSQ 603 RG +GPKG PG GPPG+ PGP PGPPG Q Sbjct: 679 GPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQ 723 Score = 150 bits (380), Expect = 2e-36 Identities = 81/182 (44%), Positives = 96/182 (52%), Gaps = 36/182 (19%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLG------------------PLGPQGPQ 498 G PGPPGPRG G G GP G G G+PG++G P GP+G + Sbjct: 1249 GPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGER 1308 Query: 499 GQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS---- 554 G+ GE+GP G GP GP+G PG G KGS G G G PGP G+ GP G +GPPG Sbjct: 1309 GEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDD 1368 Query: 555 --------------PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPP 600 PGPSGP GK G G G G++G G KGE G++GPPG GP GP Sbjct: 1369 GEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQ 1428 Query: 601 GS 602 G+ Sbjct: 1429 GA 1430 Score = 149 bits (375), Expect = 9e-36 Identities = 76/149 (51%), Positives = 86/149 (57%), Gaps = 6/149 (4%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG GPPGPR G+ G +GP G GP GDPG LGP G +G G PG G G +GP G Sbjct: 828 RGEIGPPGPR---GEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGS 884 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP---EGPPGSPGPSGPQGKPGIAGKTGS 572 GFPG G+ G G G G+PGP+G GP GP GP G G GP+G G G G Sbjct: 885 IGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGP 944 Query: 573 PGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 PG+RG GP+G G GP G PGPPG G Sbjct: 945 PGERGPNGPQGPTGFPGPKGPPGPPGKDG 973 Score = 148 bits (374), Expect = 1e-35 Identities = 79/166 (47%), Positives = 91/166 (54%), Gaps = 18/166 (10%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQG------------PQGQPGE 503 RG PG GP+G +G G+ G G +G +GDPG GP GP G P+G PGE Sbjct: 618 RGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGE 677 Query: 504 AGPVGERGPVGPRGFPG------LKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP 557 GP G GP GP G PG + G G G GP+G+PGP G G PG +G PG G Sbjct: 678 PGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGA 737 Query: 558 SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 GP G+ G GK G PG GA GP G PG +GPPG G GPPG Q Sbjct: 738 IGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQ 783 Score = 148 bits (374), Expect = 1e-35 Identities = 83/180 (46%), Positives = 91/180 (50%), Gaps = 33/180 (18%) Query: 456 RGAPGPPGPRGFKGDMGV------KGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509 RG GP GPRG +G G+ KG GG GP G PG GP GPQGP G PG GP G Sbjct: 909 RGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGP 968 Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQP------GPKGDIGPPGPEGPPGSPGPSGPQGK 563 G G G PG +G G G GP G P GP G+ GP G G PG PGP G QG Sbjct: 969 PGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGL 1028 Query: 564 PGIAGKTGS---------------------PGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 PG+AGK G+ PG RG GP G G++G G PGPPGP GS Sbjct: 1029 PGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGS 1088 Score = 147 bits (372), Expect = 2e-35 Identities = 87/174 (50%), Positives = 97/174 (55%), Gaps = 27/174 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGPVG--GR-GPKGD---PGSLGPLGPQGPQGQPGEAGPVGER 510 G PGP GP G KG +GV G G GR GPKG PG G G +G +G PG+ GP G+R Sbjct: 853 GDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQR 912 Query: 511 GPVGPRGF---------PGLKGSKGSFGTGGPRGQPGPKGDIGP---PGPEGPPGSPGPS 558 GP GPRG PG KG+ G G GP G+ GP G GP PGP+GPPG PG Sbjct: 913 GPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKD 972 Query: 559 GPQGKPG------IAGKTGSPGQRGAMGPKGEPGIQGPPGL---PGPPGPPGSQ 603 G G PG GKTG PG G +GP+G G GP G PGPPGPPG Q Sbjct: 973 GLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQ 1026 Score = 147 bits (371), Expect = 3e-35 Identities = 76/152 (50%), Positives = 90/152 (59%), Gaps = 6/152 (3%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG---PVGERGP 512 +G PGPPGP G G G GP G GP+G+PG G G G QG PG G P GE+GP Sbjct: 687 KGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGP 746 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572 +G G PG+ G+ G G G G PG KG GPPGP+GP G PGP G +G GI G G+ Sbjct: 747 LGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGT 806 Query: 573 PGQRGA---MGPKGEPGIQGPPGLPGPPGPPG 601 G++G G KG+ GI+G G GPPGP G Sbjct: 807 KGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRG 838 Score = 145 bits (365), Expect = 1e-34 Identities = 78/161 (48%), Positives = 83/161 (51%), Gaps = 15/161 (9%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG G GP G G G KGP G GPKG PG +G G GP G+PG AG G G G Sbjct: 1308 RGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGD 1367 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP---------------EGPPGSPGPSGP 560 G PG GS G G GP G PG +G GP GP EGPPG GP GP Sbjct: 1368 DGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGP 1427 Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 QG PG G G G G +G +G PG GP G PGP GPPG Sbjct: 1428 QGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPG 1468 Score = 144 bits (362), Expect = 3e-34 Identities = 83/167 (49%), Positives = 88/167 (52%), Gaps = 24/167 (14%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGPVG- 508 RG G GP G G G +GP G G KG PG GP GP QGP G PG AGPVG Sbjct: 1092 RGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGP 1151 Query: 509 --ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566 E G G G PG KGSKG G GP G GP+G IG PGP G G PGP G Q G+ Sbjct: 1152 PGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQ---GL 1208 Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLP------------GPPGPPG 601 G+ G G RG GP G G+QG PG P GPPGPPG Sbjct: 1209 FGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPG 1255 Score = 144 bits (362), Expect = 3e-34 Identities = 77/164 (46%), Positives = 89/164 (54%), Gaps = 18/164 (10%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +G PGP G +G G+ G +GP G G +G G GP GP GP G+ G+ G +GE G G Sbjct: 1110 QGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGS 1169 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP------------EGPPGSPGPSGP--- 560 +G G +G G G GP GQPGP G G PGP EGP G PGP GP Sbjct: 1170 KGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGL 1229 Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGIQGP---PGLPGPPGPPG 601 QG PG G+ G G G MGP G PG +GP PG GP GPPG Sbjct: 1230 QGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPG 1273 Score = 144 bits (362), Expect = 3e-34 Identities = 78/158 (49%), Positives = 92/158 (58%), Gaps = 15/158 (9%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGG---RGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 +G GPPGP G +G +G GP G GP+G G G G +GP+G PG GPVG +G Sbjct: 1173 KGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGL 1232 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPP---GPEGPP---GSPGPSGPQGKPGI 566 GP PG KG G G GP G PGP+G G P GP+GPP G+PG G +G+PG Sbjct: 1233 PGP---PGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGE 1289 Query: 567 AGKTGSPGQRGAMGPK---GEPGIQGPPGLPGPPGPPG 601 AG+ G PG+ G GPK GE G GP G GPPGP G Sbjct: 1290 AGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKG 1327 Score = 143 bits (361), Expect = 4e-34 Identities = 74/151 (49%), Positives = 84/151 (55%), Gaps = 3/151 (1%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG GPPGP G G G G G RG G G G G G G PGE G G+ GP GP Sbjct: 594 RGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGP 653 Query: 516 RGFPGLKGSKGSFGTGGPRG---QPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572 G PG G +G G GPRG +PGP+G +GP GP GPPG PG +G G+PG G G Sbjct: 654 PGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGP 713 Query: 573 PGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G+ G G +G PG QG PG G GPPG + Sbjct: 714 QGEPGPPGQQGNPGAQGLPGPQGAIGPPGEK 744 Score = 143 bits (360), Expect = 5e-34 Identities = 78/152 (51%), Positives = 89/152 (58%), Gaps = 12/152 (7%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP---V 513 G PGPPG G +GD G GP G G G G LGP GP GP G PG G G+ GP V Sbjct: 652 GPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNV 711 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---PGSPGPSGPQGKPGIAGKT 570 GP+G PG G +G+ G +G PGP+G IGPPG +GP PG PG G G PG GK Sbjct: 712 GPQGEPGPPGQQGN---PGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKE 768 Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G PG++G GP PG QGP G PGP G G+ Sbjct: 769 GPPGEKGGQGP---PGPQGPIGYPGPRGVKGA 797 Score = 142 bits (359), Expect = 7e-34 Identities = 77/165 (46%), Positives = 87/165 (52%), Gaps = 18/165 (10%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRG------PKGDPGSLGPLGPQGPQGQPGEAGPVGER 510 G GPPG G KG+ G GP G RG P G PG G G G +G PG+ GP G+R Sbjct: 571 GPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDR 630 Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQP---GPKGDIGPPGPEGPPGSP---------GPS 558 G G G PG KG +G G GP G P G +GD G GP G PG P GP Sbjct: 631 GFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPP 690 Query: 559 GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 GP G PG+ G G PG +G +GP+GEPG G G PG G PG Q Sbjct: 691 GPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQ 735 Score = 142 bits (359), Expect = 7e-34 Identities = 78/155 (50%), Positives = 91/155 (58%), Gaps = 24/155 (15%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG---EAGPVGERGP 512 +GAPG PGP G +G + GPVG +G G PG GP GP GP G PG ++GP GE+G Sbjct: 1428 QGAPGKPGPDGLRG---IPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGH 1484 Query: 513 ---VGPRGFPGLKGSKGSFGTGGPRGQPGPKGD------IGPPGPEGPPGSPGPSGPQGK 563 +G G PG +G KG G GP+G GPKG+ GP GP GPPG PGP GP+G Sbjct: 1485 PGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGA 1544 Query: 564 PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPG 598 G +G T GPKGE G GPPG PGPPG Sbjct: 1545 KGSSGPT---------GPKGEAGHPGPPGPPGPPG 1570 Score = 142 bits (358), Expect = 9e-34 Identities = 74/151 (49%), Positives = 83/151 (54%), Gaps = 6/151 (3%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG PGPPGP G +G + GP G +G GD G +GP GP GP+G G G G +GP G Sbjct: 1218 RGFPGPPGPVGLQG---LPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGG 1274 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 G PG G KG G G G PG G GP G G G GPSG G PG G G G Sbjct: 1275 IGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGP 1334 Query: 576 RGAMGPKGEPGIQGPPGLPGP---PGPPGSQ 603 +G+ GP G PG GPPG PGP GPPG + Sbjct: 1335 KGSPGPVGFPGDPGPPGEPGPAGQDGPPGDK 1365 Score = 141 bits (355), Expect = 2e-33 Identities = 86/210 (40%), Positives = 95/210 (45%), Gaps = 66/210 (31%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPL------------------------ 492 GA G PGPRG +G G KG GP+G PG GP+ Sbjct: 1195 GADGEPGPRGQQGLFGQKGD---EGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPP 1251 Query: 493 ---------------GPQGP------------QGQPGEAGP---VGERGPVGPRGFPGLK 522 GPQGP +G+PGEAG GE GP GP+G G K Sbjct: 1252 GPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEK 1311 Query: 523 GSKGSFGTGGPRGQPGPKGDIGP---------PGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 G G G GP G GP GD GP PG GPPG PGP+G G PG G G P Sbjct: 1312 GESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEP 1371 Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 GQ G+ GP GEPG GPPG GPPGP G + Sbjct: 1372 GQTGSPGPTGEPGPSGPPGKRGPPGPAGPE 1401 Score = 140 bits (353), Expect = 3e-33 Identities = 73/153 (47%), Positives = 86/153 (56%), Gaps = 3/153 (1%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +GA GPPG +G G G+ G G GP G PG GP G +G QG PG GP+G GP G Sbjct: 735 QGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGV 794 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPE---GPPGSPGPSGPQGKPGIAGKTGS 572 +G G++G KG+ G G G PG KGD+G G GPPG G GP+G G G G Sbjct: 795 KGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGD 854 Query: 573 PGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 PG G G KG+ G+ G PG PG GP GS F Sbjct: 855 PGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGF 887 Score = 134 bits (336), Expect = 3e-31 Identities = 74/168 (44%), Positives = 86/168 (51%), Gaps = 21/168 (12%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG----- 511 G PGPPG +G G G +G G GP G PG GP G +G G G GPVG G Sbjct: 1018 GPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNE 1077 Query: 512 ----PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA 567 P GP G PG +G G+ G G G+PGP+G GP G +G PG GP GP G+ G+ Sbjct: 1078 GPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQ 1137 Query: 568 GKTGSPGQRGAMGPKGEPGIQGPPGLP------------GPPGPPGSQ 603 G G PG G +GP GE G +G G P GPPGP G Q Sbjct: 1138 GPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQ 1185 Score = 132 bits (332), Expect = 9e-31 Identities = 75/169 (44%), Positives = 87/169 (51%), Gaps = 24/169 (14%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG---------EAGPV 507 G GPPGP G G+ G G VG RG G+PG G LGP+GP G PG + GP Sbjct: 649 GPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPK 708 Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGP---------PGPEGPPGSPGPS 558 G GP G G PG +G+ G+ G GP+G GP G+ GP PG +GPPG PG Sbjct: 709 GNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKE 768 Query: 559 GP------QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 GP QG PG G G PG RG G G G++G G G G PG Sbjct: 769 GPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPG 817 Score = 130 bits (327), Expect = 3e-30 Identities = 79/191 (41%), Positives = 95/191 (49%), Gaps = 45/191 (23%) Query: 456 RGAPGP------PGPRGFKGDMGVKGPVGGRGPKGDPG------------SLGPLGPQGP 497 +G PGP PGPRG KG G++G G +G KG+ G G +GP GP Sbjct: 777 QGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGP 836 Query: 498 QGQ------PGEAGPVGERGPVGP------------RGFPGLKGSKGSFGTGGPRGQPGP 539 +G+ G GP G+ GP+GP G+PG +G KGS G G G G Sbjct: 837 RGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGE 896 Query: 540 KGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR---GAMGPKGEP------GIQGP 590 KG G PG GP G GP+GP+G+ G G TG PG + G GP G P G QGP Sbjct: 897 KGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGP 956 Query: 591 PGLPGPPGPPG 601 G PGP GPPG Sbjct: 957 TGFPGPKGPPG 967 Score = 117 bits (292), Expect = 4e-26 Identities = 78/213 (36%), Positives = 91/213 (42%), Gaps = 56/213 (26%) Query: 444 QHGE--ILRNVTILRGAPGPPGPRGFKGDMGVKGPVGG------RGPKGDPGSLGPLGPQ 495 Q GE I+ ++ G PGP GP G G G GP G RGP G PG G G Sbjct: 454 QKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLP 513 Query: 496 GPQGQP----------GEAGPVGE--------------------RGPVGPRGFPGLKGSK 525 GP G G+AG G RGP GP G G G Sbjct: 514 GPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPV 573 Query: 526 GSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEP 585 G G+GG +G+PG D+GP GP G G PGP+G G+ G AG G+ G G GPKG+ Sbjct: 574 GPPGSGGLKGEPG---DVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDR 630 Query: 586 GIQG---------------PPGLPGPPGPPGSQ 603 G G P G PGPPG G + Sbjct: 631 GFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGER 663 Score = 115 bits (288), Expect = 1e-25 Identities = 75/196 (38%), Positives = 86/196 (43%), Gaps = 46/196 (23%) Query: 453 TILRGAPGPPGPRGFKGD-------MGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG 505 TI G GP G +G KG+ M ++GP G GP G PG G +GP G G PGE G Sbjct: 440 TIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERG 499 Query: 506 PVGERGPVGPRGFPGLKGSK----------GSFGTGGP--------------------RG 535 P G G G G PG G+ G G+ GP RG Sbjct: 500 PPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRG 559 Query: 536 QPGPKGDIGPPGPEGPPGS------PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQG 589 GP G G PGP GPPGS PG GPQG G+ G PG G G +G G G Sbjct: 560 PAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGP---PGPAGKPGRRGRAGSDG 616 Query: 590 PPGLPGPPGPPGSQSF 605 G+PG GP G + F Sbjct: 617 ARGMPGQTGPKGDRGF 632 Score = 101 bits (252), Expect = 2e-21 Identities = 53/105 (50%), Positives = 62/105 (59%), Gaps = 9/105 (8%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L+G GP G +G G +G+ GP G +G KGD G GP G GP+G+ G GP G GP G Sbjct: 1472 LKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPG 1531 Query: 515 PRGFPGL---KGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPG 556 P G PG KG+KGS G GPKG+ G PGP GPPG PG Sbjct: 1532 PPGLPGPPGPKGAKGS------SGPTGPKGEAGHPGPPGPPGPPG 1570 Score = 94.0 bits (232), Expect = 4e-19 Identities = 48/94 (51%), Positives = 54/94 (57%), Gaps = 3/94 (3%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L G GPPG +G KGD G+ GP G GPKG+ G GP GP GP G PG GP G P G Sbjct: 1487 LIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPG---PKG 1543 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548 +G G G KG G GP G PGP G++ P P Sbjct: 1544 AKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLP 1577 Score = 82.8 bits (203), Expect = 8e-16 Identities = 43/86 (50%), Positives = 51/86 (59%), Gaps = 6/86 (6%) Query: 519 PGLKGSKGSF--GTGGPRGQPGPKGD--IGPPGP--EGPPGSPGPSGPQGKPGIAGKTGS 572 PG+ ++ + G GGPRG+ G KG+ I PG EGPPG GP+G G PG G TG Sbjct: 432 PGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQ 491 Query: 573 PGQRGAMGPKGEPGIQGPPGLPGPPG 598 G G GP G PG+ G GLPGPPG Sbjct: 492 VGDPGERGPPGRPGLPGADGLPGPPG 517 Score = 53.9 bits (128), Expect = 4e-07 Identities = 26/54 (48%), Positives = 28/54 (51%) Query: 450 RNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE 503 + +T G GPPGP G G G KG G GP G G G GP GP G PGE Sbjct: 1518 QGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGE 1571 Score = 53.5 bits (127), Expect = 5e-07 Identities = 30/76 (39%), Positives = 35/76 (46%), Gaps = 18/76 (23%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQG------------------P 497 RG PGP G G KG+ G+ GP G GP G PG GP GP+G P Sbjct: 1503 RGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGP 1562 Query: 498 QGQPGEAGPVGERGPV 513 G PG G V + P+ Sbjct: 1563 PGPPGPPGEVIQPLPI 1578 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 158 bits (400), Expect = 1e-38 Identities = 78/146 (53%), Positives = 85/146 (58%), Gaps = 3/146 (2%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GAPGP GP G GD G GP G GP G G+ GP GPQGP+G GE G G+RG G R Sbjct: 1052 GAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHR 1111 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 GF GL+G G G G+ GP G GP GP GPPGS G G G G+ G G PG R Sbjct: 1112 GFSGLQGPP---GPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPR 1168 Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPGS 602 G G G G GPPG PGPPGPP + Sbjct: 1169 GRTGDAGPVGPPGPPGPPGPPGPPSA 1194 Score = 154 bits (388), Expect = 3e-37 Identities = 75/154 (48%), Positives = 88/154 (57%), Gaps = 6/154 (3%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG------EAGPVGE 509 +G GPPGP+G G+ G G G G KG+PG +G GP GP G+ G E GP G Sbjct: 421 QGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGL 480 Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGK 569 GP G RG PG +G G+ G GP+G G +G GP GP+G PG G G G PG G Sbjct: 481 PGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGL 540 Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 TGSPG G G G PG G G PGPPGPPG++ Sbjct: 541 TGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGAR 574 Score = 154 bits (388), Expect = 3e-37 Identities = 78/158 (49%), Positives = 89/158 (56%), Gaps = 18/158 (11%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG PGPPGP GF G G G G +G GD G+ G GP GP AGP G GP+G Sbjct: 802 RGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGP------AGPAGPPGPIGN 855 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEG---PPGSPGPSGPQGKPGIAGKTGS 572 G PG KG++GS G G G PG G +GPPGP G PPG PGP+G +G G G+TG Sbjct: 856 VGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGP 915 Query: 573 PGQRGAMGP---------KGEPGIQGPPGLPGPPGPPG 601 G+ G +GP KG PG GP G PG PGP G Sbjct: 916 AGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQG 953 Score = 150 bits (380), Expect = 2e-36 Identities = 77/158 (48%), Positives = 86/158 (54%), Gaps = 9/158 (5%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG GP GP G G G GPVG G GD G GP GP GP G G GP G +GP G Sbjct: 1036 RGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGD 1095 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 +G G +G +G G G G GP G G PG +GP G+ GP+GP+G PG AG G G Sbjct: 1096 KGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGL 1155 Query: 576 RGAMGPKGEPGIQ---------GPPGLPGPPGPPGSQS 604 G GP G PG + GPPG PGPPGPPG S Sbjct: 1156 NGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPS 1193 Score = 150 bits (378), Expect = 4e-36 Identities = 75/157 (47%), Positives = 90/157 (57%), Gaps = 9/157 (5%) Query: 456 RGAPGPPGPRGFKGD---MGVKGPVGGRGPKGDPGSLG------PLGPQGPQGQPGEAGP 506 RG+ GPPG GF G +G GP G GP G PG G P G GP G+PGE GP Sbjct: 865 RGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGP 924 Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566 G GP G +G PG G G+ GT GP+G G +G +G PG G G PG GP G+PG Sbjct: 925 PGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGK 984 Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G +G+ G+RG GP G PG+ GPPG G G PG++ Sbjct: 985 QGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAE 1021 Score = 149 bits (377), Expect = 6e-36 Identities = 76/156 (48%), Positives = 88/156 (56%), Gaps = 9/156 (5%) Query: 455 LRGAPGPPGPRGFKG------DMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE---AG 505 L G PG PGP+GF+G + G GP+G RGP G PG G G G G+PGE G Sbjct: 189 LPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPG 248 Query: 506 PVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPG 565 P G RG G G PG+KG +G G G +G GP G G PG G G+PG GP+G PG Sbjct: 249 PQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPG 308 Query: 566 IAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G+ G+PG GA G G G GPPG GP GPPG Sbjct: 309 ERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPG 344 Score = 149 bits (377), Expect = 6e-36 Identities = 77/155 (49%), Positives = 86/155 (55%), Gaps = 9/155 (5%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE---------AGP 506 RGA G PGP+G +GD G KG G G G G GP+GP GP G PG+ AGP Sbjct: 733 RGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGP 792 Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566 G RG G RG PG G G G G GQPG KG+ G G +G G PGP+GP G PG Sbjct: 793 TGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGP 852 Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G+PG +GA G G PG G PG G GPPG Sbjct: 853 IGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPG 887 Score = 149 bits (376), Expect = 7e-36 Identities = 83/183 (45%), Positives = 93/183 (50%), Gaps = 36/183 (19%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGS---------LGPLGPQGPQGQPGEAGPV 507 G PG G RGF G G KG G GPKG+PGS +GP G G +G+PG GP Sbjct: 260 GLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPA 319 Query: 508 GERG---------------PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP 552 G RG P GP GFPG G+KG G GPRG GP+G G PGP GP Sbjct: 320 GARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPA 379 Query: 553 GSPGPS------------GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPP 600 G+ GP+ G G PGIAG G PG RG GP+G G GP G G PG P Sbjct: 380 GAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAP 439 Query: 601 GSQ 603 GS+ Sbjct: 440 GSK 442 Score = 149 bits (376), Expect = 7e-36 Identities = 82/159 (51%), Positives = 88/159 (55%), Gaps = 15/159 (9%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PGPPG RG G G G G GPKG G G GP GP+G PGEAG GE G G + Sbjct: 479 GLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAK 538 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS---------PGPSGPQGKPGIA 567 G L GS GS G G G PGP G G PGP GPPG+ PGP G G+PG A Sbjct: 539 G---LTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA 595 Query: 568 GKTGSPGQRGAMGP---KGEPGIQGPPGLPGPPGPPGSQ 603 G+ G PG GA+GP GE G QGPPG GP G G Q Sbjct: 596 GERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQ 634 Score = 149 bits (375), Expect = 9e-36 Identities = 80/166 (48%), Positives = 91/166 (54%), Gaps = 21/166 (12%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQ---PGEAGPVGERGPV 513 G GPPGP G G G KGP G GP G PG +GP GP GP G+ PG GP G G Sbjct: 890 GNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTP 949 Query: 514 GPRGF---------PGLKGSKGSFGTGGPRGQPGPKG------DIGPPGPEGPPGSPGPS 558 GP+G PG +G +G G GP G+PG +G + GPPGP GPPG GP Sbjct: 950 GPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPP 1009 Query: 559 GPQGKPGIAGKTGSPGQ---RGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G+ G G GSPG+ GA G +GE G GPPG PG PG PG Sbjct: 1010 GESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPG 1055 Score = 148 bits (374), Expect = 1e-35 Identities = 76/149 (51%), Positives = 87/149 (58%), Gaps = 3/149 (2%) Query: 456 RGAPGPPG---PRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 RG PGPPG P G G+ G +GP G GP G+ G GP G G QG PG AGP GE G Sbjct: 598 RGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGK 657 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572 G +G PG G+ G G G RG PG +G GPPGP GP G+ G G G G AG G+ Sbjct: 658 PGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGA 717 Query: 573 PGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 PG +GA G +G PG +G GLPGP G G Sbjct: 718 PGSQGAPGLQGMPGERGAAGLPGPKGDRG 746 Score = 147 bits (370), Expect = 4e-35 Identities = 73/153 (47%), Positives = 82/153 (53%), Gaps = 6/153 (3%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG------PVGER 510 G+PG G RG G +G GP G G KG+ G GP GP G +G PG+ G P G Sbjct: 755 GSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFA 814 Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKT 570 GP G G PG KG G G G G PGP G GPPGP G G+PG G +G G G T Sbjct: 815 GPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGAT 874 Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G PG G +GP G G GPPG PGP G G + Sbjct: 875 GFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGK 907 Score = 145 bits (366), Expect = 1e-34 Identities = 75/159 (47%), Positives = 87/159 (54%), Gaps = 12/159 (7%) Query: 456 RGAPGPPGPRGFKGDM---------GVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP 506 RG+PGP GP+G G+ G KG G G G G GP GP G G+PG GP Sbjct: 511 RGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGP 570 Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS---PGPSGPQGK 563 G RG G GFPG KG+ G G G RG PGP G +GP G +G G+ PGP+GP G+ Sbjct: 571 PGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGE 630 Query: 564 PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G G GSPG +G GP G PG G PG G PG G+ Sbjct: 631 RGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGA 669 Score = 145 bits (365), Expect = 1e-34 Identities = 72/147 (48%), Positives = 81/147 (55%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG PGP G RG G G+ G G RG G G+ G GP GP+G+PG G G G +GP Sbjct: 244 RGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGP 303 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 RG PG +G G+ G G RG G G GPPGP GP G PG G G G AG G G Sbjct: 304 RGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGS 363 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G G +GEPG GP G GP G PG+ Sbjct: 364 EGPQGVRGEPGPPGPAGAAGPAGNPGA 390 Score = 144 bits (364), Expect = 2e-34 Identities = 75/146 (51%), Positives = 80/146 (54%), Gaps = 3/146 (2%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG GPPGP G +G G G G +G G PG+ G G G QG PGE G G GP G Sbjct: 685 RGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGD 744 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 RG G KG+ GS G G RG GP IGPPGP G PG G SGP G G G G+PG Sbjct: 745 RGDAGPKGADGSPGKDGVRGLTGP---IGPPGPAGAPGDKGESGPSGPAGPTGARGAPGD 801 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPG 601 RG GP G G GPPG G PG G Sbjct: 802 RGEPGPPGPAGFAGPPGADGQPGAKG 827 Score = 143 bits (361), Expect = 4e-34 Identities = 76/146 (52%), Positives = 82/146 (56%), Gaps = 3/146 (2%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RGA G PGP G G G +G G RG G G GP GP G +G PG AGP G G G Sbjct: 469 RGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGR 528 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 G GL G+KG TG P G PGP G GPPGP G G PGP GP G G AG G PG Sbjct: 529 PGEAGLPGAKGL--TGSP-GSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGP 585 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPG 601 +GA G G+ G +G PG PG GP G Sbjct: 586 KGAAGEPGKAGERGVPGPPGAVGPAG 611 Score = 143 bits (360), Expect = 5e-34 Identities = 79/172 (45%), Positives = 86/172 (50%), Gaps = 24/172 (13%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L G GPPGP G GD G GP G GP G G+ G G GP G G AGP G G G Sbjct: 765 LTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPG 824 Query: 515 PRGFPGLKGSKGSFGT---GGPRGQPGPKGDIGPPGPE---------------------G 550 +G PG G+KG G GP G PGP G++G PG + G Sbjct: 825 AKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVG 884 Query: 551 PPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 PPG G +GP G PG AGK G G RG GP G PG GPPG PGP G GS Sbjct: 885 PPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGS 936 Score = 142 bits (358), Expect = 9e-34 Identities = 76/167 (45%), Positives = 86/167 (51%), Gaps = 18/167 (10%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GA GPPGP G G G G VG +G G G G GPQG +G+PG GP G GP G Sbjct: 329 GAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNP 388 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G G G+KG+ G G G PG G GP GP+GP G PGP G G+PG G G G + Sbjct: 389 GADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAK 448 Query: 577 GAMGP---------------KGEPGIQGPPGLPGPPGP---PGSQSF 605 G GP +G G GP GLPGPPG PGS+ F Sbjct: 449 GEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGF 495 Score = 141 bits (356), Expect = 2e-33 Identities = 73/162 (45%), Positives = 90/162 (55%), Gaps = 15/162 (9%) Query: 456 RGAPGPPGPRGFKGDM------GVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509 RG PGPPG G G+ G +GP G +G +G PG+ G G +G +G G G G+ Sbjct: 220 RGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGD 279 Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS---------PGPSGP 560 GP GP+G PG G G+ G GPRG PG +G G PGP G G+ PGP+GP Sbjct: 280 AGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGP 339 Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G PG G G+ G+ G GP+G G QG G PGPPGP G+ Sbjct: 340 AGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGA 381 Score = 141 bits (355), Expect = 2e-33 Identities = 76/154 (49%), Positives = 82/154 (53%), Gaps = 9/154 (5%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPVGERGPV 513 G GPPGP G G G KG G GP G PG+ G +GP GP G G GP G G Sbjct: 845 GPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKE 904 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 G +G G G G G GP G PGP G+ G PG +GP G+PG GPQG G G G P Sbjct: 905 GGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLP 964 Query: 574 GQRGAM------GPKGEPGIQGPPGLPGPPGPPG 601 GQRG GP GEPG QGP G G GPPG Sbjct: 965 GQRGERGFPGLPGPSGEPGKQGPSGASGERGPPG 998 Score = 141 bits (355), Expect = 2e-33 Identities = 80/187 (42%), Positives = 88/187 (47%), Gaps = 42/187 (22%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRG---------PKGDPGSLGPLG------PQGPQGQP 501 GAPG PGP+G G GV G G RG P G+PG GP G P GP G P Sbjct: 944 GAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPP 1003 Query: 502 GEAGPV---------------------------GERGPVGPRGFPGLKGSKGSFGTGGPR 534 G AGP GE GP GP G PG G+ G G G Sbjct: 1004 GLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKS 1063 Query: 535 GQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP 594 G G G GP GP GP G+ GP+GPQG G G+TG G RG G +G G+QGPPG P Sbjct: 1064 GDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPP 1123 Query: 595 GPPGPPG 601 G PG G Sbjct: 1124 GSPGEQG 1130 Score = 138 bits (348), Expect = 1e-32 Identities = 75/160 (46%), Positives = 84/160 (52%), Gaps = 15/160 (9%) Query: 456 RGAPGPPGPRGFKGD------MGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509 RG PG PGP G +G+ G GP G GP G PG++G G GPQG G GP G Sbjct: 310 RGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGV 369 Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP------GPSGPQGK 563 RG GP PG G+ G G G GQPG KG G PG G PG P GP GP G Sbjct: 370 RGEPGP---PGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGP 426 Query: 564 PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 PG G +G PG G+ G G G GP G+ GPPGP G + Sbjct: 427 PGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEE 466 Score = 138 bits (348), Expect = 1e-32 Identities = 79/175 (45%), Positives = 88/175 (50%), Gaps = 30/175 (17%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGG---------RGPKGDPGSLGPLGPQGP---QGQPGEA 504 G PGPPG RG G MG GP G RG G PG++GP G G QG PG A Sbjct: 566 GPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPA 625 Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKG---DIGPPGP------------- 548 GP GERG GP G PG +G G G G G+PG +G D+G PGP Sbjct: 626 GPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGER 685 Query: 549 --EGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 +GPPG GP G G PG G G G GA G +G PG+QG PG G G PG Sbjct: 686 GVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPG 740 Score = 138 bits (347), Expect = 2e-32 Identities = 75/161 (46%), Positives = 86/161 (53%), Gaps = 12/161 (7%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLG---PLGPQGPQGQPGEAGPVGERGPV 513 G G PG +G GD+G GP G RG +G PG G P GP GP+G G G G +G Sbjct: 653 GEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDA 712 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQ---PGPKGDIGPPGPEGPPGSPGP------SGPQGKP 564 G G PG +G+ G G G RG PGPKGD G GP+G GSPG +GP G P Sbjct: 713 GAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPP 772 Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 G AG G G+ G GP G G +G PG G PGPPG F Sbjct: 773 GPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGF 813 Score = 136 bits (342), Expect = 6e-32 Identities = 82/192 (42%), Positives = 90/192 (46%), Gaps = 45/192 (23%) Query: 455 LRGAPGPPGPRGFKGDMG---------VKGPVGGRGPKGDPGSLGPLGPQGPQ------- 498 +RG PGPPGP G G G KG G G G PG G GP GPQ Sbjct: 369 VRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPG 428 Query: 499 -----------------GQPGEAGPVGERGPVGPRGFPGLKGSKGSFG----------TG 531 G GE GPVG +GP GP G G +G++G G G Sbjct: 429 PKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERG 488 Query: 532 GP--RGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQG 589 GP RG PG G GP GP G GSPGP+GP+G PG AG+ G G GA G G PG G Sbjct: 489 GPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPG 548 Query: 590 PPGLPGPPGPPG 601 P G GPPGP G Sbjct: 549 PDGKTGPPGPAG 560 Score = 135 bits (340), Expect = 1e-31 Identities = 76/157 (48%), Positives = 84/157 (53%), Gaps = 12/157 (7%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP---LGPQGPQGQPGEAGPVGERGPV 513 GA GPPGP G G+ G +GP G G +G PG GP G G QG PG+ G G G Sbjct: 617 GAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGAR 676 Query: 514 GPRGFPGLKGSKGSFGTGGPR------GQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA 567 G RGFPG +G +G G GPR G G KGD G PG G G+PG G G+ G A Sbjct: 677 GERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAA 736 Query: 568 GKTGSPGQRGAMGPK---GEPGIQGPPGLPGPPGPPG 601 G G G RG GPK G PG G GL GP GPPG Sbjct: 737 GLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPG 773 Score = 134 bits (337), Expect = 2e-31 Identities = 77/171 (45%), Positives = 90/171 (52%), Gaps = 24/171 (14%) Query: 456 RGAPGPPGPRGFKGDMGVKG------PVGGRGPKGDPGSLGPLGPQGPQGQPGEAG---- 505 +G GP GPRG +G GV+G P G GP G+PG+ G G +G G PG AG Sbjct: 352 KGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGF 411 Query: 506 --------PVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP---EGPPGS 554 P G GP GP+G G G+ GS G G +G+PGP G GPPGP EG G+ Sbjct: 412 PGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGA 471 Query: 555 PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPG---LPGPPGPPGS 602 G GP G PG G+ G PG RG G G G +GP G PGP GP GS Sbjct: 472 RGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGS 522 Score = 134 bits (336), Expect = 3e-31 Identities = 74/156 (47%), Positives = 84/156 (53%), Gaps = 9/156 (5%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGS---LGPLGPQGPQGQPGEAGPVGERG 511 L G+PG PGP G G G G G GP G PG+ G +G GP+G GE G GERG Sbjct: 540 LTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERG 599 Query: 512 PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP---GSPGPSGPQGKPGIAG 568 GP G G G G G GP G GP G+ G GP G P G PGP+GP G+ G G Sbjct: 600 VPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPG 659 Query: 569 KTGSPGQRGAMGP---KGEPGIQGPPGLPGPPGPPG 601 + G PG GA GP +GE G G G+ GPPGP G Sbjct: 660 EQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAG 695 Score = 129 bits (324), Expect = 8e-30 Identities = 74/166 (44%), Positives = 82/166 (49%), Gaps = 21/166 (12%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGP---KGDPGSLGPLGPQGPQGQPGEAGPVGERGP- 512 G PG PG G KG+ G +GP G GP +G+PG GP G GP G PG G G +G Sbjct: 341 GPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGAN 400 Query: 513 -----VGPRGFPGLKGSKGSFGTGGPRGQ---------PGPKGDIGPPGPEGPPGSPGPS 558 G GFPG +G G G GGP G PG KGD G G GP G GP Sbjct: 401 GAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPP 460 Query: 559 GPQGKPGIAGKTGSPGQRGAMGPKGE---PGIQGPPGLPGPPGPPG 601 GP G+ G G G PG G GP GE PG +G PG G GP G Sbjct: 461 GPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKG 506 Score = 128 bits (322), Expect = 1e-29 Identities = 73/168 (43%), Positives = 83/168 (49%), Gaps = 19/168 (11%) Query: 450 RNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP--- 506 + T + G G GPRG +G G G G G G PG GP GP GP G G P Sbjct: 105 QETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLS 164 Query: 507 -------------VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPG 553 G GP GPRG PG G+ G G GP G+PG G GP GP GPPG Sbjct: 165 YGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPG 224 Query: 554 SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 PG +G G+ AGK G PG+RG GP+G G+ G GLPG G G Sbjct: 225 PPGKNGDDGE---AGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRG 269 Score = 123 bits (308), Expect = 6e-28 Identities = 70/168 (41%), Positives = 78/168 (46%), Gaps = 25/168 (14%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV--------- 507 G GP G G +G G GP G G G PG GP GP GP G PG G Sbjct: 109 GVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYD 168 Query: 508 ----------GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP 557 G GP GPRG PG G+ G P+G GP G+ G PG GP G GP Sbjct: 169 EKSTGGISVPGPMGPSGPRGLPGPPGAPG------PQGFQGPPGEPGEPGASGPMGPRGP 222 Query: 558 SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 GP GK G G+ G PG+ G GP G G +G PG G PG G + F Sbjct: 223 PGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGF 270 Score = 103 bits (257), Expect = 5e-22 Identities = 62/133 (46%), Positives = 66/133 (49%), Gaps = 20/133 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GA GP GP+G +GD G G G RG KG G G GP GP G PGE GP G GP GPR Sbjct: 1082 GARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPR 1141 Query: 517 GFPG---------LKGSKGSFGTGGPRGQPG------PKGDIGPPGPEGPPG-----SPG 556 G PG L G G G GPRG+ G P G GPPGP GPP S Sbjct: 1142 GPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFL 1201 Query: 557 PSGPQGKPGIAGK 569 P PQ K G+ Sbjct: 1202 PQPPQEKAHDGGR 1214 Score = 101 bits (252), Expect = 2e-21 Identities = 62/151 (41%), Positives = 70/151 (46%), Gaps = 33/151 (21%) Query: 478 GGRGPKGDPGSLGPLGPQGPQGQP--GEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRG 535 G P+G+ + P G + P Q G GP G+ GP GPRG G G G G Sbjct: 83 GAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRG------PAGPPGRDGIPG 136 Query: 536 QPGPKGDIGPPGPEGPPG----------------------SPGPSGPQGKPGIAGKTGSP 573 QPG G GPPGP GPPG PGP GP G G+ G G+P Sbjct: 137 QPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAP 196 Query: 574 GQRGAMGP---KGEPGIQGPPGLPGPPGPPG 601 G +G GP GEPG GP G GPPGPPG Sbjct: 197 GPQGFQGPPGEPGEPGASGPMGPRGPPGPPG 227 Score = 79.3 bits (194), Expect = 9e-15 Identities = 39/80 (48%), Positives = 47/80 (58%), Gaps = 9/80 (11%) Query: 450 RNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGS---------LGPLGPQGPQGQ 500 R + L+G PGPPG G +G G GP G RGP G G+ GP+GP GP+G+ Sbjct: 1111 RGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGR 1170 Query: 501 PGEAGPVGERGPVGPRGFPG 520 G+AGPVG GP GP G PG Sbjct: 1171 TGDAGPVGPPGPPGPPGPPG 1190 Score = 65.1 bits (157), Expect = 2e-10 Identities = 40/102 (39%), Positives = 45/102 (44%), Gaps = 25/102 (24%) Query: 501 PGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGP 560 PG P GE PV P G + + G GPKGD GP GP GP G PG G Sbjct: 82 PGAEVPEGECCPVCPDGSESPTDQETT-------GVEGPKGDTGPRGPRGPAGPPGRDGI 134 Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G+PG+ PG GPPG PGPPG G+ Sbjct: 135 PGQPGL------------------PGPPGPPGPPGPPGLGGN 158 Score = 46.2 bits (108), Expect = 9e-05 Identities = 26/59 (44%), Positives = 29/59 (49%), Gaps = 8/59 (13%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLG--------PQGPQGQPGEAG 505 L G PGP GP G +G G GPVG GP G PG GP PQ PQ + + G Sbjct: 1155 LNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGG 1213 >gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 157 bits (398), Expect = 2e-38 Identities = 86/185 (46%), Positives = 101/185 (54%), Gaps = 41/185 (22%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG------------EA 504 G PG PG G G MG G +G GPKG+ G +GP GP GP+G+PG E Sbjct: 387 GPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEV 446 Query: 505 GPVGERG---PVGPRGFPGLKGSKGSFGTGG---PRGQPG------------------PK 540 GP G RG P+GP+G G KG G G G P+G+PG P Sbjct: 447 GPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPS 506 Query: 541 GDIGPPGPEGPPGSPGPSGPQ-----GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPG 595 G IGPPG GP G PG GP GKPG+AG G PG+ GA+GP+G+PG+ GPPG PG Sbjct: 507 GPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPG 566 Query: 596 PPGPP 600 PPGPP Sbjct: 567 PPGPP 571 Score = 149 bits (377), Expect = 6e-36 Identities = 82/166 (49%), Positives = 92/166 (55%), Gaps = 20/166 (12%) Query: 456 RGAPGPPGPRGFK--GDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE---- 509 +G PG PGP G G G GP G RG G PG+LGP G +GP G PG GP GE Sbjct: 336 QGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLP 395 Query: 510 --RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD------------IGPPGPEGPPGSP 555 GP+GP G G G KG G GP+G PGPKG+ +G GP G G P Sbjct: 396 GIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLP 455 Query: 556 GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 GP GP+G+ G G G PG G +GPKGEPGI G GL GPPG PG Sbjct: 456 GPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPG 501 Score = 142 bits (357), Expect = 1e-33 Identities = 87/195 (44%), Positives = 96/195 (49%), Gaps = 49/195 (25%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG--- 511 L G PGPPG G G G GP G RG G PG+LGP G +GP G PG GP GE G Sbjct: 338 LPGLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPG 396 Query: 512 ---PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD------------IGPPGPEGPPGSPG 556 P+GP G G G KG G GP+G PGPKG+ +G GP G G PG Sbjct: 397 IPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPG 456 Query: 557 PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGI------QGPPG------------------ 592 P GP+G+ G G G PG G +GPKGEPGI QGPPG Sbjct: 457 PIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPG 516 Query: 593 ------LPGPPGPPG 601 LPGPPG PG Sbjct: 517 PKGEPGLPGPPGFPG 531 Score = 138 bits (347), Expect = 2e-32 Identities = 85/179 (47%), Positives = 93/179 (51%), Gaps = 30/179 (16%) Query: 457 GAPGPPGPRGFKG--DMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG------ 508 G GPPGP G G GV G G +GP G PG+ G GPQGP G PG GP G Sbjct: 258 GMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGK 317 Query: 509 --ERGPVGPRGFPGLKGSKGSFGTGGPRGQPG--------PKGD---------IGPPGPE 549 + G G GFPG KG +G G GP G PG PKGD +GP G + Sbjct: 318 PGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEK 377 Query: 550 GPPGSPGPSGPQGKPG---IAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 GP G+PG GP G+PG I G G PG G GPKGE GI GP G PGP G PG Q F Sbjct: 378 GPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGF 436 Score = 135 bits (340), Expect = 1e-31 Identities = 76/155 (49%), Positives = 87/155 (56%), Gaps = 14/155 (9%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG PG G G G KG +G +G G G GP GP GP G PG +G+ G G Sbjct: 161 GMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG----IGKPGGPGLP 216 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGD-----IGPPGPEGPPGSPGPSGPQGKPGIA--GK 569 G PG KG +G G GP+G GPKGD G PG +GPPG GP GP G PG+ G Sbjct: 217 GQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGV 276 Query: 570 TGSPGQRGAM---GPKGEPGIQGPPGLPGPPGPPG 601 TG PG +G + G GEPG QGP G+PG GPPG Sbjct: 277 TGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPG 311 Score = 118 bits (296), Expect = 1e-26 Identities = 72/174 (41%), Positives = 86/174 (49%), Gaps = 35/174 (20%) Query: 462 PGPRGFKGDMGVKGPV-------GGRGPKGDPGSLGPLGPQGPQGQ-----PGEAGPVGE 509 P PR K + KG G +GP+G+PG GP GP G G G+ GP G Sbjct: 95 PAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGY 154 Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQ--GKPGIA 567 G VG G PG+ G G+ G G +G+ G KG+IGP G GP G PGP G GKPG Sbjct: 155 PG-VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGP 213 Query: 568 GKTGSPGQRGAMGPK--------------------GEPGIQGPPGLPGPPGPPG 601 G G PG +G GPK G PG++GPPG+ GPPGP G Sbjct: 214 GLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVG 267 Score = 100 bits (250), Expect = 3e-21 Identities = 65/149 (43%), Positives = 71/149 (47%), Gaps = 18/149 (12%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG PG G KG+ G+ G G +GP G PG GP GP GP G PG P GE G GP Sbjct: 471 GLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPG---PKGEPGLPGPP 527 Query: 517 GFPG--------LKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPG----SPGPSG---PQ 561 GFPG L G G G GP+GQPG G GPPGP GPP +P P G P Sbjct: 528 GFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPD 587 Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGP 590 GI G G G P + P Sbjct: 588 MGLGIDGVKPPHAYGAKKGKNGGPAYEMP 616 Score = 69.3 bits (168), Expect = 1e-11 Identities = 35/70 (50%), Positives = 42/70 (60%), Gaps = 8/70 (11%) Query: 534 RGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGL 593 RG+ GP+G+ GP GP GPPG PG G PGI GK G G G G+PG+ G PG Sbjct: 117 RGEQGPRGEPGPRGPPGPPGLPG----HGIPGIKGKPGPQGYPGV----GKPGMPGMPGK 168 Query: 594 PGPPGPPGSQ 603 PG G PG++ Sbjct: 169 PGAMGMPGAK 178 Score = 47.4 bits (111), Expect = 4e-05 Identities = 34/101 (33%), Positives = 43/101 (42%), Gaps = 8/101 (7%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L G PG PG G +G G+ GP G GP G P + P P PQG+ +G G Sbjct: 540 LHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPP--PQGEYLPDMGLGIDGVKP 597 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP 555 P + KG G G P ++ P P P G+P Sbjct: 598 PHAYGAKKGKNG----GPAYEMPAFTAELTAPFP--PVGAP 632 Score = 43.5 bits (101), Expect = 6e-04 Identities = 40/131 (30%), Positives = 50/131 (38%), Gaps = 27/131 (20%) Query: 491 PLGPQGPQGQPGEAG---PVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG 547 PL PQ P P + P+G++ P P GL G+ P G Sbjct: 35 PLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLA-----------MGKEMPHLQYGKEY 83 Query: 548 PEGPPG----SPGPS-GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP----- 597 P P P P G + P + RG GP+GEPG +GPPG PG P Sbjct: 84 PHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIP 143 Query: 598 ---GPPGSQSF 605 G PG Q + Sbjct: 144 GIKGKPGPQGY 154 >gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 157 bits (398), Expect = 2e-38 Identities = 86/185 (46%), Positives = 101/185 (54%), Gaps = 41/185 (22%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG------------EA 504 G PG PG G G MG G +G GPKG+ G +GP GP GP+G+PG E Sbjct: 387 GPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEV 446 Query: 505 GPVGERG---PVGPRGFPGLKGSKGSFGTGG---PRGQPG------------------PK 540 GP G RG P+GP+G G KG G G G P+G+PG P Sbjct: 447 GPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPS 506 Query: 541 GDIGPPGPEGPPGSPGPSGPQ-----GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPG 595 G IGPPG GP G PG GP GKPG+AG G PG+ GA+GP+G+PG+ GPPG PG Sbjct: 507 GPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPG 566 Query: 596 PPGPP 600 PPGPP Sbjct: 567 PPGPP 571 Score = 149 bits (377), Expect = 6e-36 Identities = 82/166 (49%), Positives = 92/166 (55%), Gaps = 20/166 (12%) Query: 456 RGAPGPPGPRGFK--GDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE---- 509 +G PG PGP G G G GP G RG G PG+LGP G +GP G PG GP GE Sbjct: 336 QGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLP 395 Query: 510 --RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD------------IGPPGPEGPPGSP 555 GP+GP G G G KG G GP+G PGPKG+ +G GP G G P Sbjct: 396 GIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLP 455 Query: 556 GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 GP GP+G+ G G G PG G +GPKGEPGI G GL GPPG PG Sbjct: 456 GPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPG 501 Score = 142 bits (357), Expect = 1e-33 Identities = 87/195 (44%), Positives = 96/195 (49%), Gaps = 49/195 (25%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG--- 511 L G PGPPG G G G GP G RG G PG+LGP G +GP G PG GP GE G Sbjct: 338 LPGLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPG 396 Query: 512 ---PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD------------IGPPGPEGPPGSPG 556 P+GP G G G KG G GP+G PGPKG+ +G GP G G PG Sbjct: 397 IPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPG 456 Query: 557 PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGI------QGPPG------------------ 592 P GP+G+ G G G PG G +GPKGEPGI QGPPG Sbjct: 457 PIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPG 516 Query: 593 ------LPGPPGPPG 601 LPGPPG PG Sbjct: 517 PKGEPGLPGPPGFPG 531 Score = 138 bits (347), Expect = 2e-32 Identities = 85/179 (47%), Positives = 93/179 (51%), Gaps = 30/179 (16%) Query: 457 GAPGPPGPRGFKG--DMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG------ 508 G GPPGP G G GV G G +GP G PG+ G GPQGP G PG GP G Sbjct: 258 GMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGK 317 Query: 509 --ERGPVGPRGFPGLKGSKGSFGTGGPRGQPG--------PKGD---------IGPPGPE 549 + G G GFPG KG +G G GP G PG PKGD +GP G + Sbjct: 318 PGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEK 377 Query: 550 GPPGSPGPSGPQGKPG---IAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 GP G+PG GP G+PG I G G PG G GPKGE GI GP G PGP G PG Q F Sbjct: 378 GPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGF 436 Score = 135 bits (340), Expect = 1e-31 Identities = 76/155 (49%), Positives = 87/155 (56%), Gaps = 14/155 (9%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG PG G G G KG +G +G G G GP GP GP G PG +G+ G G Sbjct: 161 GMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG----IGKPGGPGLP 216 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGD-----IGPPGPEGPPGSPGPSGPQGKPGIA--GK 569 G PG KG +G G GP+G GPKGD G PG +GPPG GP GP G PG+ G Sbjct: 217 GQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGV 276 Query: 570 TGSPGQRGAM---GPKGEPGIQGPPGLPGPPGPPG 601 TG PG +G + G GEPG QGP G+PG GPPG Sbjct: 277 TGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPG 311 Score = 118 bits (296), Expect = 1e-26 Identities = 72/174 (41%), Positives = 86/174 (49%), Gaps = 35/174 (20%) Query: 462 PGPRGFKGDMGVKGPV-------GGRGPKGDPGSLGPLGPQGPQGQ-----PGEAGPVGE 509 P PR K + KG G +GP+G+PG GP GP G G G+ GP G Sbjct: 95 PAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGY 154 Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQ--GKPGIA 567 G VG G PG+ G G+ G G +G+ G KG+IGP G GP G PGP G GKPG Sbjct: 155 PG-VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGP 213 Query: 568 GKTGSPGQRGAMGPK--------------------GEPGIQGPPGLPGPPGPPG 601 G G PG +G GPK G PG++GPPG+ GPPGP G Sbjct: 214 GLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVG 267 Score = 100 bits (250), Expect = 3e-21 Identities = 65/149 (43%), Positives = 71/149 (47%), Gaps = 18/149 (12%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG PG G KG+ G+ G G +GP G PG GP GP GP G PG P GE G GP Sbjct: 471 GLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPG---PKGEPGLPGPP 527 Query: 517 GFPG--------LKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPG----SPGPSG---PQ 561 GFPG L G G G GP+GQPG G GPPGP GPP +P P G P Sbjct: 528 GFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPD 587 Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGP 590 GI G G G P + P Sbjct: 588 MGLGIDGVKPPHAYGAKKGKNGGPAYEMP 616 Score = 69.3 bits (168), Expect = 1e-11 Identities = 35/70 (50%), Positives = 42/70 (60%), Gaps = 8/70 (11%) Query: 534 RGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGL 593 RG+ GP+G+ GP GP GPPG PG G PGI GK G G G G+PG+ G PG Sbjct: 117 RGEQGPRGEPGPRGPPGPPGLPG----HGIPGIKGKPGPQGYPGV----GKPGMPGMPGK 168 Query: 594 PGPPGPPGSQ 603 PG G PG++ Sbjct: 169 PGAMGMPGAK 178 Score = 47.4 bits (111), Expect = 4e-05 Identities = 34/101 (33%), Positives = 43/101 (42%), Gaps = 8/101 (7%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L G PG PG G +G G+ GP G GP G P + P P PQG+ +G G Sbjct: 540 LHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPP--PQGEYLPDMGLGIDGVKP 597 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP 555 P + KG G G P ++ P P P G+P Sbjct: 598 PHAYGAKKGKNG----GPAYEMPAFTAELTAPFP--PVGAP 632 Score = 43.5 bits (101), Expect = 6e-04 Identities = 40/131 (30%), Positives = 50/131 (38%), Gaps = 27/131 (20%) Query: 491 PLGPQGPQGQPGEAG---PVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG 547 PL PQ P P + P+G++ P P GL G+ P G Sbjct: 35 PLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLA-----------MGKEMPHLQYGKEY 83 Query: 548 PEGPPG----SPGPS-GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP----- 597 P P P P G + P + RG GP+GEPG +GPPG PG P Sbjct: 84 PHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIP 143 Query: 598 ---GPPGSQSF 605 G PG Q + Sbjct: 144 GIKGKPGPQGY 154 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 157 bits (397), Expect = 3e-38 Identities = 80/149 (53%), Positives = 89/149 (59%), Gaps = 6/149 (4%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG GPRG G +G GP G G KG+ G+ G G GP+G PGE G E GP GP Sbjct: 753 GVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERG---ETGPPGPA 809 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 GFPG G G G G RG PG KG+ GPPG GPPG GP+GP G G+ G+ GSPG Sbjct: 810 GFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGP 869 Query: 577 GAMGPKGEPGIQGPPGL---PGPPGPPGS 602 GA G G G+ GPPG PGPPGP GS Sbjct: 870 GAAGFPGARGLPGPPGSNGNPGPPGPSGS 898 Score = 157 bits (396), Expect = 3e-38 Identities = 82/164 (50%), Positives = 91/164 (55%), Gaps = 18/164 (10%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE------------ 503 RG G PGP+G KG+ G G G G G G GP+GP GP GQPG+ Sbjct: 731 RGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGI 790 Query: 504 AGP------VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP 557 AGP GE GP GP GFPG G G G G RG PG KG+ GPPG GPPG GP Sbjct: 791 AGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGP 850 Query: 558 SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 +GP G G+ G+ GSPG GA G G G+ GPPG G PGPPG Sbjct: 851 AGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPG 894 Score = 157 bits (396), Expect = 3e-38 Identities = 79/149 (53%), Positives = 87/149 (58%), Gaps = 6/149 (4%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG GPPGP GF G G G GG+G +G PG G GP G G PG +GP G GP G Sbjct: 800 RGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGV 859 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 +G G G G+ G G RG PGP G G PGP GP GSPG GP PG AG TG+PG Sbjct: 860 KGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGP---PGPAGNTGAPGS 916 Query: 576 RGAMGPK---GEPGIQGPPGLPGPPGPPG 601 G GPK G+PG +G PG GPPG PG Sbjct: 917 PGVSGPKGDAGQPGEKGSPGAQGPPGAPG 945 Score = 151 bits (381), Expect = 2e-36 Identities = 78/157 (49%), Positives = 85/157 (54%), Gaps = 12/157 (7%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGER------ 510 G PGP GP G G+ G +GP G GP GD G GP GPQG QG PG GP GE Sbjct: 600 GGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEP 659 Query: 511 GPVGPRGFPGLKGSKGSFGTGGPR------GQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564 GP G G PG G KG G G R G PG +G GPPGPEG G+ GP GP G Sbjct: 660 GPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAA 719 Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G G PG+RG +G G G +G PG PG G PG Sbjct: 720 GTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPG 756 Score = 150 bits (378), Expect = 4e-36 Identities = 75/145 (51%), Positives = 79/145 (54%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PGP GP G GD G GP G G G GS G GPQGP+G GE G G G G R Sbjct: 1050 GPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHR 1109 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 GFPG G+ GS G G +G G G GP GP GP G PG G G PG G G G R Sbjct: 1110 GFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNR 1169 Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPG 601 G G +G PG G PG PGPPG PG Sbjct: 1170 GERGSEGSPGHPGQPGPPGPPGAPG 1194 Score = 149 bits (376), Expect = 7e-36 Identities = 77/162 (47%), Positives = 85/162 (52%), Gaps = 15/162 (9%) Query: 457 GAPGPPGPRGFKGDMGVKGPVG---------------GRGPKGDPGSLGPLGPQGPQGQP 501 G PGP GPRG G MG GP G G GP+G PG G GPQGP G Sbjct: 564 GPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPT 623 Query: 502 GEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQ 561 G G G+ GP GP+G GL G+ G G G G+PGPKGD G PG G G G G + Sbjct: 624 GPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGER 683 Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G PG+AG G G G GP+G G GPPG PG G PG Q Sbjct: 684 GPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQ 725 Score = 147 bits (370), Expect = 4e-35 Identities = 75/148 (50%), Positives = 82/148 (55%), Gaps = 3/148 (2%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG PG G G +G G GP GG+G G PG G G G QG PGE G +G GP G Sbjct: 683 RGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGD 742 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 +G PG G+ G G GPR GP G IGPPGP G PG G G G PGIAG GSPG+ Sbjct: 743 KGEPGGPGADGVPGKDGPR---GPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGE 799 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 RG GP G G G PG G PG G + Sbjct: 800 RGETGPPGPAGFPGAPGQNGEPGGKGER 827 Score = 145 bits (366), Expect = 1e-34 Identities = 75/159 (47%), Positives = 88/159 (55%), Gaps = 12/159 (7%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G+ G PGP G +G+ G GP G GP+G PG +G GP+G G PG+ G G G GP+ Sbjct: 546 GSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQ 605 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGP------QGKPGIAGKT 570 G PG G G G GP G G KGD GPPGP+G G PG GP G+PG G Sbjct: 606 GPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDA 665 Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPP------GPPGSQ 603 G+PG G G G PG +GPPGL G P GPPG + Sbjct: 666 GAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPE 704 Score = 144 bits (364), Expect = 2e-34 Identities = 77/154 (50%), Positives = 86/154 (55%), Gaps = 6/154 (3%) Query: 456 RGAPGPPG---PRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE---AGPVGE 509 RG PGPPG P G G G+KG G G G+ G G G +G G PGE GP+G Sbjct: 242 RGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGP 301 Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGK 569 RG G RG PGL G+ G+ G G RG G G GPPG G PGSPG G G G G Sbjct: 302 RGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGS 361 Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G+PGQRG GP+G G QGPPG PG G PG + Sbjct: 362 NGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGK 395 Score = 144 bits (364), Expect = 2e-34 Identities = 78/169 (46%), Positives = 85/169 (50%), Gaps = 24/169 (14%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP---LGPQGPQGQPGEAGPVGERGPV 513 G PGPPGP G G G GP G G G PG GP G G +G PG GP G GP+ Sbjct: 888 GNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPL 947 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGP---KGDIGPPGPEGPPGSPGPSGPQGKPGIA--- 567 G G G +G G G GPRG PGP KG+ G PG G G GP GPQG PG+A Sbjct: 948 GIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTA 1007 Query: 568 ---------------GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G+ GSPG +G G G PG G PG PGPPGP G Sbjct: 1008 GEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVG 1056 Score = 144 bits (363), Expect = 2e-34 Identities = 75/163 (46%), Positives = 85/163 (52%), Gaps = 18/163 (11%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGG------RGPKGDPGSLGPLGPQGPQGQPGEAGPVGER 510 G GPPGP+G KG+ G G G RG G PGS G GP GP G PG+ GP G Sbjct: 849 GPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPA 908 Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP------------EGPPGSPGPS 558 G G G PG+ G KG G G +G PG +G G PGP GPPG PGP Sbjct: 909 GNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPR 968 Query: 559 GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G G+ G++G PG G G +G PG QG PGL G G PG Sbjct: 969 GSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPG 1011 Score = 144 bits (362), Expect = 3e-34 Identities = 79/158 (50%), Positives = 87/158 (55%), Gaps = 18/158 (11%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLG---------PLGPQGPQGQPGEAGP 506 RGAPGP GPRG G+ G G GG G +G PGS G P G QG G+PG GP Sbjct: 509 RGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGP 568 Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566 G RG G GFPG KG+ G+ G G RG P G PGP+GPPG G +GPQG PG Sbjct: 569 SGPRGQPGVMGFPGPKGNDGAPGKNGERGGP------GGPGPQGPPGKNGETGPQGPPGP 622 Query: 567 AGKTGSPGQRGAMGP---KGEPGIQGPPGLPGPPGPPG 601 G G G G GP +G PG GPPG G PG PG Sbjct: 623 TGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPG 660 Score = 143 bits (361), Expect = 4e-34 Identities = 74/170 (43%), Positives = 89/170 (52%), Gaps = 24/170 (14%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE------- 509 G PGPPGP G G G G G +GP G+PG GP GP GP G G +GP G+ Sbjct: 177 GPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRP 236 Query: 510 --------------RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP 555 +GP G GFPG+KG +G G G +G+ G G G G G G+P Sbjct: 237 GRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAP 296 Query: 556 GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 GP GP+G P G+ G PG GA G +G G +G G PGPPGPPG+ F Sbjct: 297 GPMGPRGAP---GERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGF 343 Score = 143 bits (361), Expect = 4e-34 Identities = 77/163 (47%), Positives = 88/163 (53%), Gaps = 15/163 (9%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP------VGE 509 +G+PG GP G G +G+ G G RG G PG GP G GPQG GE+G GE Sbjct: 932 KGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGE 991 Query: 510 RGPVGPRGFPGL---------KGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGP 560 RGP GP+G PGL G+ GS G G G PG KGD G G G PG+PG GP Sbjct: 992 RGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGP 1051 Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G G AGK+G G+ G GP G PG G G PGP GP G + Sbjct: 1052 PGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDK 1094 Score = 142 bits (357), Expect = 1e-33 Identities = 74/156 (47%), Positives = 83/156 (53%), Gaps = 9/156 (5%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG+PG PG GF G G+ GP G G G PG G G GP G G G G G GP Sbjct: 863 RGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGP 922 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGP---------KGDIGPPGPEGPPGSPGPSGPQGKPGI 566 +G G G KGS G GP G PGP +G GPPG GP GSPGP G +G+ G Sbjct: 923 KGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGK 982 Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G G G+RG GP+G PG+ G G PG G PGS Sbjct: 983 PGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGS 1018 Score = 140 bits (354), Expect = 3e-33 Identities = 72/147 (48%), Positives = 82/147 (55%), Gaps = 3/147 (2%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L G G PG +G +G+ G G G G G PG +GP G G +G+ G AGP G GP G Sbjct: 1021 LPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAG 1080 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574 RG PG +G +G G G RG G KG G PG G PGSPGP+G Q G G G G Sbjct: 1081 SRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQ---GAIGSPGPAG 1137 Query: 575 QRGAMGPKGEPGIQGPPGLPGPPGPPG 601 RG +GP G PG G G PGP GPPG Sbjct: 1138 PRGPVGPSGPPGKDGTSGHPGPIGPPG 1164 Score = 140 bits (354), Expect = 3e-33 Identities = 72/151 (47%), Positives = 83/151 (54%), Gaps = 6/151 (3%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGP---QGQPGEAGPVGERGPV 513 G+PG PG G G G GP G G +G+ G GP G GP +G PG GP G++G Sbjct: 1038 GSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGET 1097 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 G RG G+KG +G G G G PGP G G G GP G GP GP G PG G +G P Sbjct: 1098 GERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHP 1157 Query: 574 GQRGAMGP---KGEPGIQGPPGLPGPPGPPG 601 G G GP +GE G +G PG PG PGPPG Sbjct: 1158 GPIGPPGPRGNRGERGSEGSPGHPGQPGPPG 1188 Score = 139 bits (351), Expect = 6e-33 Identities = 79/170 (46%), Positives = 83/170 (48%), Gaps = 21/170 (12%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L G PG PGPRG G GVKG G G G G GP GPQG G G AG G G G Sbjct: 958 LAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPG 1017 Query: 515 PRGFPGLKGS---------KGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPG 565 G PG GS GS G G G PGP G +GP G G G GP+GP G PG Sbjct: 1018 SDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPG 1077 Query: 566 IAGKTGSP------------GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 AG G+P G+RGA G KG G G PG PG PGP G Q Sbjct: 1078 PAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQ 1127 Score = 139 bits (350), Expect = 8e-33 Identities = 72/154 (46%), Positives = 83/154 (53%), Gaps = 9/154 (5%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GAPG G G +G G +GP G G G PG G +GP G G PG G G GP G Sbjct: 363 GAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGAN 422 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP---------GSPGPSGPQGKPGIA 567 G PGL+G G G G +G+PGP+G+ G G G P GSPG G G PG A Sbjct: 423 GAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAA 482 Query: 568 GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G+ G+PG RG GP G PG +GP G G PGP G Sbjct: 483 GERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAG 516 Score = 138 bits (348), Expect = 1e-32 Identities = 82/184 (44%), Positives = 91/184 (49%), Gaps = 39/184 (21%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP------------------LGPQGPQ 498 GA G PGPRG +G+ G+ G G +G G GS G GP GP Sbjct: 438 GAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPN 497 Query: 499 GQPGEAGPVGERG---PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS- 554 G PGE GP GERG P GPRG G G G G G RG PG G G G GPPGS Sbjct: 498 GIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQ 557 Query: 555 --------PGPSGPQGKPGI------AGKTGSPGQRGAMGPKGEPGIQGPPGL---PGPP 597 PGPSGP+G+PG+ G G+PG+ G G G PG QGPPG GP Sbjct: 558 GESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQ 617 Query: 598 GPPG 601 GPPG Sbjct: 618 GPPG 621 Score = 138 bits (348), Expect = 1e-32 Identities = 79/173 (45%), Positives = 87/173 (50%), Gaps = 27/173 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG-------- 508 G PG G G KGD G G G G G PG GP+GP G G GE+GP G Sbjct: 1020 GLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPA 1079 Query: 509 -ERGPVGP------------RGFPGLKGSKGSFGTGGPRGQPGP---KGDIGPPGPEGPP 552 RG GP RG G+KG +G G G G PGP +G IG PGP GP Sbjct: 1080 GSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPR 1139 Query: 553 GSPGPSGPQGKPGIA---GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G GPSGP GK G + G G PG RG G +G G G PG PGPPGPPG+ Sbjct: 1140 GPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGA 1192 Score = 137 bits (346), Expect = 2e-32 Identities = 74/152 (48%), Positives = 83/152 (54%), Gaps = 9/152 (5%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGR------GPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509 +G PGP GP G KGD G GP G + GP G+ G G GP+G G PG G G+ Sbjct: 617 QGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGD 676 Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGK 569 G G RG PGL G+ G G GP PGP+G G GP GPPG+ G G QG PG G Sbjct: 677 AGAPGERGPPGLAGAPGLRGGAGP---PGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGG 733 Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 GSPG +G G G PG G PG GP GP G Sbjct: 734 LGSPGPKGDKGEPGGPGADGVPGKDGPRGPTG 765 Score = 137 bits (345), Expect = 3e-32 Identities = 78/186 (41%), Positives = 91/186 (48%), Gaps = 39/186 (20%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +G GPPGP+G +G G GP G G G+PG G G G G G+AG GERGP G Sbjct: 629 KGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGL 688 Query: 516 RGFPGLK---------GSKGSFGTGGP------------------RGQPGPKGDIGPP-- 546 G PGL+ G KG+ G GP G PGPKGD G P Sbjct: 689 AGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGG 748 Query: 547 ----------GPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGP 596 GP GP G GP GP G+PG G+ G+PG G GP+G PG +G G PGP Sbjct: 749 PGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGP 808 Query: 597 PGPPGS 602 G PG+ Sbjct: 809 AGFPGA 814 Score = 135 bits (341), Expect = 8e-32 Identities = 77/164 (46%), Positives = 85/164 (51%), Gaps = 18/164 (10%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPVGERGPV 513 G PG G RGF G G KG G G KG+ PG G GP GP+G PGE G G G Sbjct: 258 GFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAA 317 Query: 514 GPRGFPGLKGSKGSFGTGGPRG------QPGPKGDIGP---------PGPEGPPGSPGPS 558 G RG G +GS G G GP G PG KG++GP PG G PG G + Sbjct: 318 GARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHA 377 Query: 559 GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G QG PG G GSPG +G MGP G PG G G GPPGP G+ Sbjct: 378 GAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGA 421 Score = 135 bits (340), Expect = 1e-31 Identities = 78/170 (45%), Positives = 89/170 (52%), Gaps = 29/170 (17%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLG-----PQGPQGQP--------- 501 +G PGPPG G GD G+ G G PGS GP G P GPQ Sbjct: 108 KGDPGPPGIPGRNGDPGIPGQ------PGSPGSPGPPGICESCPTGPQNYSPQYDSYDVK 161 Query: 502 ------GEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP 555 G AG G GP GP G PG G GS G+ G +G PG G GP GP GPPG+ Sbjct: 162 SGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAI 221 Query: 556 GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 GPSGP GK G +G+ G PG+RG GP PGI+GP G+PG PG G + F Sbjct: 222 GPSGPAGKDGESGRPGRPGERGLPGP---PGIKGPAGIPGFPGMKGHRGF 268 Score = 135 bits (340), Expect = 1e-31 Identities = 76/161 (47%), Positives = 83/161 (51%), Gaps = 15/161 (9%) Query: 456 RGAPGP---PGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 RG GP PG +G G+ G GP G RG G+PG G G G +G PG G G G Sbjct: 491 RGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGK 550 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQ------PGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566 GP G G G G G GPRGQ PGPKG+ G PG G G PG GPQG PG Sbjct: 551 PGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGK 610 Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPP------GLPGPPGPPG 601 G+TG G G GP G+ G GPP GLPG GPPG Sbjct: 611 NGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPG 651 Score = 135 bits (339), Expect = 1e-31 Identities = 71/147 (48%), Positives = 77/147 (52%), Gaps = 3/147 (2%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 LRG G PG G KG+ GP G RG G PG G G G G PGE G G G G Sbjct: 427 LRGGAGEPGKNGAKGE---PGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAG 483 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574 RG PG +G G G G +G G +G GP GP G G PG G G PG+ G GSPG Sbjct: 484 ERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPG 543 Query: 575 QRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G+ G G PG QG G PGPPGP G Sbjct: 544 GPGSDGKPGPPGSQGESGRPGPPGPSG 570 Score = 134 bits (338), Expect = 2e-31 Identities = 80/171 (46%), Positives = 84/171 (49%), Gaps = 24/171 (14%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG----- 511 G+PG PG G G G +G G RGP G G G GP G +G PG AGP G G Sbjct: 468 GSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRD 527 Query: 512 --PVGP--RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPG------PSGPQ 561 P GP RG PG G GS G GP G G G GPPGP GP G PG P G Sbjct: 528 GVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGND 587 Query: 562 GKPGIAGKTGSPGQRGAMGP---KGEPGIQGPPGLPGP------PGPPGSQ 603 G PG G+ G PG G GP GE G QGPPG GP GPPG Q Sbjct: 588 GAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQ 638 Score = 134 bits (337), Expect = 2e-31 Identities = 78/180 (43%), Positives = 91/180 (50%), Gaps = 33/180 (18%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQG------------QPGEA 504 GA GPPGP G G G KG +G G G PG +G GP GP G +PG+ Sbjct: 378 GAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKN 437 Query: 505 GPVGERGPVGPRG---FPGLKGSKGSFGTGGPRGQPGPKG------------DIGPPGPE 549 G GE GP G RG PG+ G+KG G G G+PG G GP GP Sbjct: 438 GAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPN 497 Query: 550 GPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPG------PPGPPGSQ 603 G PG GP+G +G PG AG G+ G+ G G G PG++G PG PG PGPPGSQ Sbjct: 498 GIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQ 557 Score = 133 bits (335), Expect = 4e-31 Identities = 72/148 (48%), Positives = 81/148 (54%), Gaps = 9/148 (6%) Query: 457 GAPGPPGPRGFKGDMG---VKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPV 513 GAPGP GPRG G+ G + G G RG G GS G GP GP G G G G +G V Sbjct: 294 GAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEV 353 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 GP G PG G+ G RG+PGP+G G GP GPPG G G +G+ G AG G+P Sbjct: 354 GPAGSPGSNGAPGQ------RGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAP 407 Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G GA GP G G G PGL G G PG Sbjct: 408 GLMGARGPPGPAGANGAPGLRGGAGEPG 435 Score = 130 bits (327), Expect = 3e-30 Identities = 74/162 (45%), Positives = 86/162 (53%), Gaps = 15/162 (9%) Query: 456 RGAPGPPGPRGFKGDMGVKGP---------VGGRGPKGDPGSLGPLGPQGPQGQPGEAGP 506 +G PGPPG G G G GP +G RGP G G+ G G +G G+PG+ G Sbjct: 380 QGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGA 439 Query: 507 VGERGPVGPR---GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGK 563 GE GP G R G PG+ G+KG G G G+PG G G G G PG GP+GP G Sbjct: 440 KGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGI 499 Query: 564 P---GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 P G AG+ G+PG G G GEPG G PG PG G PGS Sbjct: 500 PGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGS 541 Score = 121 bits (303), Expect = 2e-27 Identities = 67/133 (50%), Positives = 74/133 (55%), Gaps = 7/133 (5%) Query: 456 RGAPGPPGPRGFKGDMGVKGPV---GGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 RGAPGP GPRG KG+ G +G G RG G+PG+ G GP G QG G GP G RGP Sbjct: 1082 RGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGP 1141 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGK-TG 571 VGP G PG G+ G GP G PGP+G+ G G EG PG PG GP G PG G G Sbjct: 1142 VGPSGPPGKDGTSGH---PGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCG 1198 Query: 572 SPGQRGAMGPKGE 584 G G GE Sbjct: 1199 GVGAAAIAGIGGE 1211 Score = 101 bits (252), Expect = 2e-21 Identities = 58/143 (40%), Positives = 65/143 (45%), Gaps = 23/143 (16%) Query: 482 PKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKG 541 P G+ ++ P P P P GP G +G GP G PG G G G G G PGP G Sbjct: 80 PFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPG 139 Query: 542 --DIGPPGPE---------------------GPPGSPGPSGPQGKPGIAGKTGSPGQRGA 578 + P GP+ G PG GP GP G PG +G GSPG G Sbjct: 140 ICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGY 199 Query: 579 MGPKGEPGIQGPPGLPGPPGPPG 601 GP GEPG GP G PGPPG G Sbjct: 200 QGPPGEPGQAGPSGPPGPPGAIG 222 Score = 42.0 bits (97), Expect = 0.002 Identities = 23/58 (39%), Positives = 24/58 (41%), Gaps = 18/58 (31%) Query: 545 PPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 P P PP GP GP+G PG PGI G G PG PG PGS Sbjct: 92 PTAPTRPPNGQGPQGPKGDPG------------------PPGIPGRNGDPGIPGQPGS 131 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 157 bits (396), Expect = 3e-38 Identities = 78/161 (48%), Positives = 92/161 (57%), Gaps = 15/161 (9%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PGPPGP G G G +G G G G+PG GP GP G +G+PG+ GP G GP GP+ Sbjct: 915 GPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQ 974 Query: 517 GF---------PGLKGSKGSFGTGGPRGQPGPKG------DIGPPGPEGPPGSPGPSGPQ 561 G PG +G +G G GP G+PG +G D GPPGP GPPG GP+G Sbjct: 975 GLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEP 1034 Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G+ G G G PG+ GA G KG+ G G G PG PGPPGS Sbjct: 1035 GREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS 1075 Score = 156 bits (395), Expect = 5e-38 Identities = 79/145 (54%), Positives = 84/145 (57%), Gaps = 3/145 (2%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G+PGP GP G +GD G G G GP G G+ G GPQGP+G GEAG GERG G R Sbjct: 1074 GSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHR 1133 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 GF GL+G G GP G G G GP GP GPPG GPSG G GI G G PG R Sbjct: 1134 GFTGLQGLPGP---PGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPR 1190 Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPG 601 G G G G G PG PGPPGPPG Sbjct: 1191 GRSGETGPAGPPGNPGPPGPPGPPG 1215 Score = 152 bits (384), Expect = 9e-37 Identities = 76/152 (50%), Positives = 84/152 (55%), Gaps = 6/152 (3%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLG---PQGPQGQPGEAGPVGERGP 512 RG GPPGP GF G G G G +G +G+ G G G PQGP G PG GP G GP Sbjct: 824 RGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGP 883 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572 G RG G G+ G G G G PG G+ GPPGP GP G GP G +G G G+ G Sbjct: 884 KGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 943 Query: 573 PGQRGAMGP---KGEPGIQGPPGLPGPPGPPG 601 PG +G GP KGEPG GP G GPPGP G Sbjct: 944 PGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQG 975 Score = 151 bits (381), Expect = 2e-36 Identities = 80/167 (47%), Positives = 90/167 (53%), Gaps = 21/167 (12%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG------- 508 RGA G GP+G +GD+G KGP G G G G GP+GP GP G GE G VG Sbjct: 755 RGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGS 814 Query: 509 -----------ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP 557 E GP GP GF G G+ G G G +G+ G KGD G PGP+GP G+PGP Sbjct: 815 AGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGP 874 Query: 558 SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGL---PGPPGPPG 601 GP G G G G+ G GA G G G GPPG PGPPGPPG Sbjct: 875 QGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 921 Score = 150 bits (380), Expect = 2e-36 Identities = 81/154 (52%), Positives = 88/154 (57%), Gaps = 9/154 (5%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PGP GP G +G+ G GP G +G G PG G G G QG PGEAG G GP G R Sbjct: 642 GPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGER 701 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGP---PGPEGPPGSPGPSGPQGKP------GIA 567 GFPG +GS G+ G GPRG PG G GP GP GPPG+ GP G QG P GIA Sbjct: 702 GFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIA 761 Query: 568 GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G G G GP+G PG G GL GP GPPG Sbjct: 762 GPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPG 795 Score = 149 bits (377), Expect = 6e-36 Identities = 74/147 (50%), Positives = 84/147 (57%), Gaps = 6/147 (4%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GAPG G G G+ G GP+G RG G+ G GP G G +G G+ GP G GPVGP Sbjct: 303 GAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPA 362 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G PG G+ G+ G GP G GP+G GP G G PGSPGP+G G PG G G+ G Sbjct: 363 GGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSA 422 Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 GA PGI G PG PGP GPPG Q Sbjct: 423 GA------PGIAGAPGFPGPRGPPGPQ 443 Score = 149 bits (377), Expect = 6e-36 Identities = 79/151 (52%), Positives = 85/151 (56%), Gaps = 9/151 (5%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GAPG PGP G G GP G +G +G+ G+ GP+GP GP G G GP G RG G Sbjct: 1065 GAPGAPGP---PGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEA 1121 Query: 517 GFP---GLKGSKGSFGTGGPRGQPGPKGD---IGPPGPEGPPGSPGPSGPQGKPGIAGKT 570 G P GLKG +G G G G PGP GD GP GP GP G PGP GP GK G G Sbjct: 1122 GEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIP 1181 Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G G G GE G GPPG PGPPGPPG Sbjct: 1182 GPIGPPGPRGRSGETGPAGPPGNPGPPGPPG 1212 Score = 147 bits (372), Expect = 2e-35 Identities = 84/174 (48%), Positives = 88/174 (50%), Gaps = 27/174 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGG---RGPKGDPGSLGPLGPQGPQGQPG---------EA 504 G+PGP GPRG G+ G GP G RG G PG GP GP GP G PG EA Sbjct: 318 GSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEA 377 Query: 505 GPVGERGPVG---PRGFPGLKGSKGSFGTGGPRGQ---PGPKGDIGPPGPEGPPGSPGPS 558 GP G RGP G PRG PG GS G G G G PG KG G PG G PG PGP Sbjct: 378 GPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPR 437 Query: 559 GPQGKPGIAGKTGSPGQ---------RGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 GP G G G G GQ +G GPKGEPG GP G PGP G G + Sbjct: 438 GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKR 491 Score = 147 bits (371), Expect = 3e-35 Identities = 75/151 (49%), Positives = 82/151 (54%), Gaps = 6/151 (3%) Query: 457 GAPGPPGPRGFKGDMGV------KGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGER 510 G PG PGP G G+ G KG G G G PG GP GP GPQG G GP G+ Sbjct: 396 GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQT 455 Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKT 570 G G GF G +G KG G GP+G PGP G+ G G G PG GP GP G+ G G Sbjct: 456 GEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNR 515 Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G PGQ G GPKG PG +GP GL GP G G Sbjct: 516 GFPGQDGLAGPKGAPGERGPSGLAGPKGANG 546 Score = 147 bits (370), Expect = 4e-35 Identities = 73/147 (49%), Positives = 82/147 (55%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG PGP G RGF G G+ G G RG G G+ G G G +G+ G G G GP+GP Sbjct: 266 RGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP 325 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 RG PG +G G G G RG G G GPPGP GP G PG G G G AG TG+ G Sbjct: 326 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 385 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPGS 602 GA GP+GEPG G PG G G PG+ Sbjct: 386 EGAQGPRGEPGTPGSPGPAGASGNPGT 412 Score = 147 bits (370), Expect = 4e-35 Identities = 83/186 (44%), Positives = 93/186 (50%), Gaps = 39/186 (20%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GA GPPGP+G G G+ G G RG +G PG GP G G QG PG +G G GPVGP Sbjct: 966 GAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPP 1025 Query: 517 GF------PGLKGSKGSFGTGGPRGQPGPKGD------IGPPGPEGPPGSPGPSGPQGKP 564 G PG +GS G+ G G G G KGD +G PG GPPGSPGP+GP GK Sbjct: 1026 GLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQ 1085 Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGP---------------------------PGLPGPP 597 G G+ G+ G G GP G GIQGP GLPGPP Sbjct: 1086 GDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPP 1145 Query: 598 GPPGSQ 603 GP G Q Sbjct: 1146 GPSGDQ 1151 Score = 146 bits (369), Expect = 5e-35 Identities = 76/170 (44%), Positives = 88/170 (51%), Gaps = 21/170 (12%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP-------- 506 + GAPG PGPRG G G GP+G +G G+PG G G QGP+G+PG AGP Sbjct: 427 IAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAG 486 Query: 507 -------------VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPG 553 VG GP G RG PG +G G G GP+G PG +G G GP+G G Sbjct: 487 EEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANG 546 Query: 554 SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 PG G G PG G TG PG G G G G G G PGPPGP G++ Sbjct: 547 DPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGAR 596 Score = 145 bits (365), Expect = 1e-34 Identities = 74/151 (49%), Positives = 82/151 (54%), Gaps = 6/151 (3%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GAPGP GP G G G +G G G G PG+ G +GP G G PG GP G G GP+ Sbjct: 870 GAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPK 929 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G G G G G G +G GP G+ G PG +GP G+ GP GPQG G G G PGQR Sbjct: 930 GARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQR 989 Query: 577 GAM------GPKGEPGIQGPPGLPGPPGPPG 601 G GP GEPG QG PG G GPPG Sbjct: 990 GERGFPGLPGPSGEPGKQGAPGASGDRGPPG 1020 Score = 144 bits (363), Expect = 2e-34 Identities = 72/151 (47%), Positives = 86/151 (56%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L+G PG G G G G +G VG +GP+G PG G G GP G PG AG GE+G VG Sbjct: 748 LQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVG 807 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574 P G G G++G+ G G G PGP G GPPG +G PG+ G G G+ G AG G G Sbjct: 808 PPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQG 867 Query: 575 QRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 GA GP+G G+ GP G G GPPG+ F Sbjct: 868 PSGAPGPQGPTGVTGPKGARGAQGPPGATGF 898 Score = 143 bits (361), Expect = 4e-34 Identities = 77/159 (48%), Positives = 92/159 (57%), Gaps = 12/159 (7%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV---GERGP 512 +G G PG GFKG+ G KG G GP+G PG G G +G +G+PG GP+ GERG Sbjct: 452 KGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGA 511 Query: 513 VGPRGFP---GLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA-- 567 G RGFP GL G KG+ G GP G GPKG G PG G PG PG G G+PG A Sbjct: 512 PGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGP 571 Query: 568 ----GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G +G+PG+ G GP G G +G PG+ G PGP G+ Sbjct: 572 QGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGA 610 Score = 142 bits (358), Expect = 9e-34 Identities = 77/161 (47%), Positives = 88/161 (54%), Gaps = 15/161 (9%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE---AGPVGERGPV 513 GA G GPRG G G GP G GP G PG+ GP G QG G+ G AGP G+RG V Sbjct: 711 GAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV 770 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGP------KGDIGPPGP------EGPPGSPGPSGPQ 561 G +G G G G G GP G PGP KG++GPPGP G PG G +GP Sbjct: 771 GEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPP 830 Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G G AG G+ GQ GA G +GE G +G G PGP GP G+ Sbjct: 831 GPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGA 871 Score = 142 bits (358), Expect = 9e-34 Identities = 70/150 (46%), Positives = 84/150 (56%), Gaps = 3/150 (2%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GA GPPG +G G+ G G G +G +GD G GP G G G G GP+G GP G Sbjct: 741 GAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGAN 800 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEG---PPGSPGPSGPQGKPGIAGKTGSP 573 G G G G G+ G RG PG +G+ GPPGP G PPG+ G G +G+ G AG+ G Sbjct: 801 GEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDA 860 Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G G GP G PG QGP G+ GP G G+Q Sbjct: 861 GAPGPQGPSGAPGPQGPTGVTGPKGARGAQ 890 Score = 141 bits (356), Expect = 2e-33 Identities = 77/161 (47%), Positives = 91/161 (56%), Gaps = 18/161 (11%) Query: 456 RGAPGP---PGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 RG PGP PGP+GF+G+ G G G GP G G GP G G G+ G+ G GERGP Sbjct: 209 RGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGP 268 Query: 513 VGPRG---------FPGLKGSKGSFGTGGPRGQ---PGPKGDIGPPGPEGPPGSPGPSGP 560 GP+G PG+KG +G G G +G+ PG KG+ G PG GSPGP GP Sbjct: 269 PGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN---GSPGPMGP 325 Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 +G PG G+TG G GA G G+PG GPPG GP G PG Sbjct: 326 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPG 366 Score = 140 bits (352), Expect = 4e-33 Identities = 77/167 (46%), Positives = 91/167 (54%), Gaps = 18/167 (10%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQ---PGEAGPVGERGPV 513 G GPPGP G G G G G +G G G+ GP G QGP+G+ PG GP G G Sbjct: 351 GPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNP 410 Query: 514 GPRGFPGLKGSKGSFGTG------GPRGQPGPKGDIGPPGPEGPPGSP------GPSGPQ 561 G G PG KGS G+ G GPRG PGP+G GP GP+G G P G GP+ Sbjct: 411 GTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPK 470 Query: 562 GKPGIAGKTGSP---GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 G+PG AG G+P G+ G G +GEPG GP G PG G PG++ F Sbjct: 471 GEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGF 517 Score = 139 bits (351), Expect = 6e-33 Identities = 75/159 (47%), Positives = 84/159 (52%), Gaps = 12/159 (7%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKG---DPGSLGPLGPQGPQGQPGEAGPVGERGPV 513 G GP G RGF G+ G G G +GP+G PG+ GP G GP G PG GP G +G Sbjct: 693 GLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMP 752 Query: 514 GPRGFPGL---KGSKGSFGTGGPRGQPGP------KGDIGPPGPEGPPGSPGPSGPQGKP 564 G RG G+ KG +G G GP G PG G IGPPGP G G G GP G Sbjct: 753 GERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPA 812 Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G AG G+PG+RG GP G G GPPG G PG G Q Sbjct: 813 GSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQ 851 Score = 139 bits (350), Expect = 8e-33 Identities = 73/159 (45%), Positives = 89/159 (55%), Gaps = 12/159 (7%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQG------QPGEAGPVGER 510 G PGPPGP+G +G GV G G +G G+PG G G G G + GE G G Sbjct: 585 GRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPP 644 Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPG---SPGPSGPQGKPGIA 567 GP GP G G +G+ G G G G PGP G+ G PG +G PG +PG GP+G+ G Sbjct: 645 GPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFP 704 Query: 568 GKTGSPGQRGAMGPK---GEPGIQGPPGLPGPPGPPGSQ 603 G+ GSPG +G GP+ G PG GP G GP GPPG+Q Sbjct: 705 GERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQ 743 Score = 137 bits (346), Expect = 2e-32 Identities = 79/175 (45%), Positives = 86/175 (49%), Gaps = 30/175 (17%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G GPPG RG G+ G G G GPKG PG GP G GP+G G+ G GE G G R Sbjct: 501 GPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR 560 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPG------PSGPQGKPGIAGK- 569 G G G G G GP G PG G GPPGP+G G PG P G G+PG AG+ Sbjct: 561 GLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEK 620 Query: 570 --TGSPGQRGAMGPKGEPGIQGPP---------------------GLPGPPGPPG 601 G+PG RG G GE G GPP GLPGPPGPPG Sbjct: 621 GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPG 675 Score = 137 bits (344), Expect = 4e-32 Identities = 73/153 (47%), Positives = 86/153 (56%), Gaps = 12/153 (7%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG------EAGPVGER 510 G PG G G G G G G RGP G G+ GPLGP+G G+PG E GP GE Sbjct: 414 GIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 473 Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKT 570 GP GP+G PG G +G G RG+PG G IGPPG G PG+ G G+ G+AG Sbjct: 474 GPAGPQGAPGPAGEEGK---RGARGEPGGVGPIGPPGERGAPGN---RGFPGQDGLAGPK 527 Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G+PG+RG G G G G PG PG PG PG++ Sbjct: 528 GAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR 560 Score = 136 bits (343), Expect = 5e-32 Identities = 76/172 (44%), Positives = 93/172 (54%), Gaps = 27/172 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG-- 514 G PG PG +G G G +GP G +GP+G+PG+ G GP G G PG G G +G G Sbjct: 366 GFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAP 425 Query: 515 ----------PRGFPGLKGSKGSFGTGGPRGQPGP---KGDIGP---PGPEGPPGSPGPS 558 PRG PG +G+ G G G G+PG KG+ GP PGP GP G+PGP+ Sbjct: 426 GIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA 485 Query: 559 GPQGK------PGIAGKTGSPGQRGAMGPKGEP---GIQGPPGLPGPPGPPG 601 G +GK PG G G PG+RGA G +G P G+ GP G PG GP G Sbjct: 486 GEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSG 537 Score = 136 bits (343), Expect = 5e-32 Identities = 73/157 (46%), Positives = 80/157 (50%), Gaps = 9/157 (5%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVG---------GRGPKGDPGSLGPLGPQGPQGQPGEAGP 506 +GAPG GP G G G G G RG G PG GP G GP G PGE G Sbjct: 527 KGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGR 586 Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566 G GP G RG PG+ G G G G G+ G KG G PG G PG G +G G PG Sbjct: 587 PGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP 646 Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 AG G G++GA GP G G+ GPPG PG G PG Q Sbjct: 647 AGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQ 683 Score = 135 bits (341), Expect = 8e-32 Identities = 74/152 (48%), Positives = 80/152 (52%), Gaps = 3/152 (1%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG PG RG G G GP G GP G PG G GP GPQG G+ G +G GP G Sbjct: 552 GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 611 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G PG G KG G G RG PG G+ G GP GP G G G QG PG +G G PG Sbjct: 612 GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP 671 Query: 577 GAMGPKGEPGIQGPPGLPGPP---GPPGSQSF 605 G G G+PG QG PG G P GP G + F Sbjct: 672 GPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 703 Score = 135 bits (340), Expect = 1e-31 Identities = 76/188 (40%), Positives = 93/188 (49%), Gaps = 33/188 (17%) Query: 449 LRNVTILRGAPGPPGP------RGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG 502 ++++ +G PGP GP RG +GD G KG G RG G+PG+ G GP GP G PG Sbjct: 112 IKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPG 171 Query: 503 E---------------------------AGPVGERGPVGPRGFPGLKGSKGSFGTGGPRG 535 GP+G GP GP G G G +G G G G Sbjct: 172 PPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG 231 Query: 536 QPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPG 595 +PG G +GP GP GPPG PG G GKPG AG+ G PG +GA G G PG+ G G G Sbjct: 232 EPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRG 291 Query: 596 PPGPPGSQ 603 PG G++ Sbjct: 292 YPGLDGAK 299 Score = 135 bits (339), Expect = 1e-31 Identities = 72/160 (45%), Positives = 87/160 (54%), Gaps = 15/160 (9%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G G GP G G+ G GP G +G +G PG +G GP+G G+PG+AG G G G R Sbjct: 570 GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLR 629 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G PG G G+ G GP G G +G+ G PGP G G PGP GP G+ G G G PG+ Sbjct: 630 GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA 689 Query: 577 GA---MGPKGE------------PGIQGPPGLPGPPGPPG 601 GA +GP+GE G+QGP GLPG PG G Sbjct: 690 GAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDG 729 Score = 133 bits (334), Expect = 5e-31 Identities = 77/195 (39%), Positives = 91/195 (46%), Gaps = 46/195 (23%) Query: 457 GAPGPPGPRGFKGDM----------GVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP 506 G PGP G +G GD+ G +GP G +GP+GD G G G GP+G+ GE G Sbjct: 98 GQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT 157 Query: 507 VGERGPVGPRGFPGLKGSKGSF------------------------GTGGPRGQPGPKGD 542 G GP GP G PG G G+F G GPRG PGP G Sbjct: 158 PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGA 217 Query: 543 IGPPGPEGPPGSPG------------PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGP 590 GP G +G PG PG P GP GKPG G+ G PG+ G GP G G +G Sbjct: 218 PGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGF 277 Query: 591 PGLPGPPGPPGSQSF 605 PG PG PG G + + Sbjct: 278 PGTPGLPGVKGHRGY 292 Score = 132 bits (333), Expect = 7e-31 Identities = 73/158 (46%), Positives = 88/158 (55%), Gaps = 12/158 (7%) Query: 456 RGAPGP---PGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQ---GPQGQPGEAGPVGE 509 +GAPGP G RG +G+ G GP+G G +G PG+ G G GP+G PGE GP G Sbjct: 479 QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGL 538 Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQP---GPKGDIGP---PGPEGPPGSPGPSGPQGK 563 GP G G PG G G G G G+P GP+G +GP PG +G PG PGP G +G+ Sbjct: 539 AGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ 598 Query: 564 PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 PG+ G G G G G GE G+ G PGL G PG G Sbjct: 599 PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDG 636 Score = 102 bits (253), Expect = 1e-21 Identities = 63/169 (37%), Positives = 72/169 (42%), Gaps = 49/169 (28%) Query: 482 PKGDPGSLGPLGPQGPQGQPGEAGPVGERGPV-------------------GPRGFPGLK 522 P G+ + P GQPG G GE G + GPRG G K Sbjct: 81 PFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDK 140 Query: 523 GSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP--------------------------- 555 G KG+ G G G+PG G+ GPPGP GPPG P Sbjct: 141 GEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQ 200 Query: 556 ---GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 GP GP+G PG AG G G +G G GEPG+ GP G GPPGPPG Sbjct: 201 GPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPG 249 Score = 89.0 bits (219), Expect = 1e-17 Identities = 51/114 (44%), Positives = 56/114 (49%), Gaps = 15/114 (13%) Query: 450 RNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509 R T L+G PGPPGP GD G GP G GP+G PG P GP G+ G G G Sbjct: 1133 RGFTGLQGLPGPPGP---SGDQGASGPAGPSGPRGPPG------PVGPSGKDGANGIPGP 1183 Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGK 563 GP GPR G G G GP G PGP G GPPGP + GP+ K Sbjct: 1184 IGPPGPR------GRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREK 1231 Score = 42.0 bits (97), Expect = 0.002 Identities = 30/91 (32%), Positives = 34/91 (37%), Gaps = 37/91 (40%) Query: 548 PEGPPGSPGPSGPQGKPGIAGKTGSPGQRG-------AMGPKGEPGIQGP---------- 590 PE P G P P +G+ G GQ+G +GPKG PG QGP Sbjct: 78 PEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDR 137 Query: 591 --------------------PGLPGPPGPPG 601 PG PGPPGPPG Sbjct: 138 GDKGEKGAPGPRGRDGEPGTPGNPGPPGPPG 168 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 157 bits (396), Expect = 3e-38 Identities = 78/161 (48%), Positives = 92/161 (57%), Gaps = 15/161 (9%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PGPPGP G G G +G G G G+PG GP GP G +G+PG+ GP G GP GP+ Sbjct: 846 GPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQ 905 Query: 517 GF---------PGLKGSKGSFGTGGPRGQPGPKG------DIGPPGPEGPPGSPGPSGPQ 561 G PG +G +G G GP G+PG +G D GPPGP GPPG GP+G Sbjct: 906 GLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEP 965 Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G+ G G G PG+ GA G KG+ G G G PG PGPPGS Sbjct: 966 GREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS 1006 Score = 156 bits (395), Expect = 5e-38 Identities = 79/145 (54%), Positives = 84/145 (57%), Gaps = 3/145 (2%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G+PGP GP G +GD G G G GP G G+ G GPQGP+G GEAG GERG G R Sbjct: 1005 GSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHR 1064 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 GF GL+G G GP G G G GP GP GPPG GPSG G GI G G PG R Sbjct: 1065 GFTGLQGLPGP---PGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPR 1121 Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPG 601 G G G G G PG PGPPGPPG Sbjct: 1122 GRSGETGPAGPPGNPGPPGPPGPPG 1146 Score = 152 bits (384), Expect = 9e-37 Identities = 76/152 (50%), Positives = 84/152 (55%), Gaps = 6/152 (3%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLG---PQGPQGQPGEAGPVGERGP 512 RG GPPGP GF G G G G +G +G+ G G G PQGP G PG GP G GP Sbjct: 755 RGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGP 814 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572 G RG G G+ G G G G PG G+ GPPGP GP G GP G +G G G+ G Sbjct: 815 KGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 874 Query: 573 PGQRGAMGP---KGEPGIQGPPGLPGPPGPPG 601 PG +G GP KGEPG GP G GPPGP G Sbjct: 875 PGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQG 906 Score = 151 bits (381), Expect = 2e-36 Identities = 80/167 (47%), Positives = 90/167 (53%), Gaps = 21/167 (12%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV-------- 507 RGA G GP+G +GD+G KGP G G G G GP+GP GP G GE G V Sbjct: 686 RGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGS 745 Query: 508 ----------GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP 557 GE GP GP GF G G+ G G G +G+ G KGD G PGP+GP G+PGP Sbjct: 746 AGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGP 805 Query: 558 SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGL---PGPPGPPG 601 GP G G G G+ G GA G G G GPPG PGPPGPPG Sbjct: 806 QGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 852 Score = 150 bits (380), Expect = 2e-36 Identities = 81/154 (52%), Positives = 88/154 (57%), Gaps = 9/154 (5%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PGP GP G +G+ G GP G +G G PG G G G QG PGEAG G GP G R Sbjct: 573 GPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGER 632 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGP---PGPEGPPGSPGPSGPQGKP------GIA 567 GFPG +GS G+ G GPRG PG G GP GP GPPG+ GP G QG P GIA Sbjct: 633 GFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIA 692 Query: 568 GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G G G GP+G PG G GL GP GPPG Sbjct: 693 GPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPG 726 Score = 149 bits (377), Expect = 6e-36 Identities = 74/147 (50%), Positives = 84/147 (57%), Gaps = 6/147 (4%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GAPG G G G+ G GP+G RG G+ G GP G G +G G+ GP G GPVGP Sbjct: 234 GAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPA 293 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G PG G+ G+ G GP G GP+G GP G G PGSPGP+G G PG G G+ G Sbjct: 294 GGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSA 353 Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 GA PGI G PG PGP GPPG Q Sbjct: 354 GA------PGIAGAPGFPGPRGPPGPQ 374 Score = 149 bits (377), Expect = 6e-36 Identities = 79/151 (52%), Positives = 85/151 (56%), Gaps = 9/151 (5%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GAPG PGP G G GP G +G +G+ G+ GP+GP GP G G GP G RG G Sbjct: 996 GAPGAPGP---PGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEA 1052 Query: 517 GFP---GLKGSKGSFGTGGPRGQPGPKGD---IGPPGPEGPPGSPGPSGPQGKPGIAGKT 570 G P GLKG +G G G G PGP GD GP GP GP G PGP GP GK G G Sbjct: 1053 GEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIP 1112 Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G G G GE G GPPG PGPPGPPG Sbjct: 1113 GPIGPPGPRGRSGETGPAGPPGNPGPPGPPG 1143 Score = 147 bits (372), Expect = 2e-35 Identities = 84/174 (48%), Positives = 88/174 (50%), Gaps = 27/174 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGG---RGPKGDPGSLGPLGPQGPQGQPG---------EA 504 G+PGP GPRG G+ G GP G RG G PG GP GP GP G PG EA Sbjct: 249 GSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEA 308 Query: 505 GPVGERGPVG---PRGFPGLKGSKGSFGTGGPRGQ---PGPKGDIGPPGPEGPPGSPGPS 558 GP G RGP G PRG PG GS G G G G PG KG G PG G PG PGP Sbjct: 309 GPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPR 368 Query: 559 GPQGKPGIAGKTGSPGQ---------RGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 GP G G G G GQ +G GPKGEPG GP G PGP G G + Sbjct: 369 GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKR 422 Score = 147 bits (371), Expect = 3e-35 Identities = 75/151 (49%), Positives = 82/151 (54%), Gaps = 6/151 (3%) Query: 457 GAPGPPGPRGFKGDMGV------KGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGER 510 G PG PGP G G+ G KG G G G PG GP GP GPQG G GP G+ Sbjct: 327 GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQT 386 Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKT 570 G G GF G +G KG G GP+G PGP G+ G G G PG GP GP G+ G G Sbjct: 387 GEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNR 446 Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G PGQ G GPKG PG +GP GL GP G G Sbjct: 447 GFPGQDGLAGPKGAPGERGPSGLAGPKGANG 477 Score = 147 bits (370), Expect = 4e-35 Identities = 73/147 (49%), Positives = 82/147 (55%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG PGP G RGF G G+ G G RG G G+ G G G +G+ G G G GP+GP Sbjct: 197 RGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP 256 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 RG PG +G G G G RG G G GPPGP GP G PG G G G AG TG+ G Sbjct: 257 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 316 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPGS 602 GA GP+GEPG G PG G G PG+ Sbjct: 317 EGAQGPRGEPGTPGSPGPAGASGNPGT 343 Score = 147 bits (370), Expect = 4e-35 Identities = 83/186 (44%), Positives = 93/186 (50%), Gaps = 39/186 (20%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GA GPPGP+G G G+ G G RG +G PG GP G G QG PG +G G GPVGP Sbjct: 897 GAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPP 956 Query: 517 GF------PGLKGSKGSFGTGGPRGQPGPKGD------IGPPGPEGPPGSPGPSGPQGKP 564 G PG +GS G+ G G G G KGD +G PG GPPGSPGP+GP GK Sbjct: 957 GLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQ 1016 Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGP---------------------------PGLPGPP 597 G G+ G+ G G GP G GIQGP GLPGPP Sbjct: 1017 GDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPP 1076 Query: 598 GPPGSQ 603 GP G Q Sbjct: 1077 GPSGDQ 1082 Score = 146 bits (369), Expect = 5e-35 Identities = 76/170 (44%), Positives = 88/170 (51%), Gaps = 21/170 (12%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP-------- 506 + GAPG PGPRG G G GP+G +G G+PG G G QGP+G+PG AGP Sbjct: 358 IAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAG 417 Query: 507 -------------VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPG 553 VG GP G RG PG +G G G GP+G PG +G G GP+G G Sbjct: 418 EEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANG 477 Query: 554 SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 PG G G PG G TG PG G G G G G G PGPPGP G++ Sbjct: 478 DPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGAR 527 Score = 145 bits (365), Expect = 1e-34 Identities = 74/151 (49%), Positives = 82/151 (54%), Gaps = 6/151 (3%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GAPGP GP G G G +G G G G PG+ G +GP G G PG GP G G GP+ Sbjct: 801 GAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPK 860 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G G G G G G +G GP G+ G PG +GP G+ GP GPQG G G G PGQR Sbjct: 861 GARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQR 920 Query: 577 GAM------GPKGEPGIQGPPGLPGPPGPPG 601 G GP GEPG QG PG G GPPG Sbjct: 921 GERGFPGLPGPSGEPGKQGAPGASGDRGPPG 951 Score = 144 bits (363), Expect = 2e-34 Identities = 72/151 (47%), Positives = 86/151 (56%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L+G PG G G G G +G VG +GP+G PG G G GP G PG AG GE+G VG Sbjct: 679 LQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVG 738 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574 P G G G++G+ G G G PGP G GPPG +G PG+ G G G+ G AG G G Sbjct: 739 PPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQG 798 Query: 575 QRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 GA GP+G G+ GP G G GPPG+ F Sbjct: 799 PSGAPGPQGPTGVTGPKGARGAQGPPGATGF 829 Score = 143 bits (361), Expect = 4e-34 Identities = 77/159 (48%), Positives = 92/159 (57%), Gaps = 12/159 (7%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV---GERGP 512 +G G PG GFKG+ G KG G GP+G PG G G +G +G+PG GP+ GERG Sbjct: 383 KGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGA 442 Query: 513 VGPRGFP---GLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA-- 567 G RGFP GL G KG+ G GP G GPKG G PG G PG PG G G+PG A Sbjct: 443 PGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGP 502 Query: 568 ----GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G +G+PG+ G GP G G +G PG+ G PGP G+ Sbjct: 503 QGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGA 541 Score = 142 bits (358), Expect = 9e-34 Identities = 77/161 (47%), Positives = 88/161 (54%), Gaps = 15/161 (9%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE---AGPVGERGPV 513 GA G GPRG G G GP G GP G PG+ GP G QG G+ G AGP G+RG V Sbjct: 642 GAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV 701 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGP------KGDIGPPGP------EGPPGSPGPSGPQ 561 G +G G G G G GP G PGP KG++GPPGP G PG G +GP Sbjct: 702 GEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPP 761 Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G G AG G+ GQ GA G +GE G +G G PGP GP G+ Sbjct: 762 GPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGA 802 Score = 142 bits (358), Expect = 9e-34 Identities = 70/150 (46%), Positives = 84/150 (56%), Gaps = 3/150 (2%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GA GPPG +G G+ G G G +G +GD G GP G G G G GP+G GP G Sbjct: 672 GAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGAN 731 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEG---PPGSPGPSGPQGKPGIAGKTGSP 573 G G G G G+ G RG PG +G+ GPPGP G PPG+ G G +G+ G AG+ G Sbjct: 732 GEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDA 791 Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G G GP G PG QGP G+ GP G G+Q Sbjct: 792 GAPGPQGPSGAPGPQGPTGVTGPKGARGAQ 821 Score = 141 bits (356), Expect = 2e-33 Identities = 77/161 (47%), Positives = 91/161 (56%), Gaps = 18/161 (11%) Query: 456 RGAPGP---PGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 RG PGP PGP+GF+G+ G G G GP G G GP G G G+ G+ G GERGP Sbjct: 140 RGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGP 199 Query: 513 VGPRG---------FPGLKGSKGSFGTGGPRGQ---PGPKGDIGPPGPEGPPGSPGPSGP 560 GP+G PG+KG +G G G +G+ PG KG+ G PG GSPGP GP Sbjct: 200 PGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN---GSPGPMGP 256 Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 +G PG G+TG G GA G G+PG GPPG GP G PG Sbjct: 257 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPG 297 Score = 140 bits (353), Expect = 3e-33 Identities = 74/172 (43%), Positives = 87/172 (50%), Gaps = 18/172 (10%) Query: 450 RNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509 R +T G PGP G G KG++G GP G G +G PG G GP GP G G G G+ Sbjct: 716 RGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQ 775 Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGK 569 G G +G G KG G+ G GP G PGP+G G GP+G G+ GP G G PG AG+ Sbjct: 776 PGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGR 835 Query: 570 TGSPGQ------------------RGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G PG +GA G G PG G PGL GP GPPG + Sbjct: 836 VGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEK 887 Score = 140 bits (352), Expect = 4e-33 Identities = 77/167 (46%), Positives = 91/167 (54%), Gaps = 18/167 (10%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQ---PGEAGPVGERGPV 513 G GPPGP G G G G G +G G G+ GP G QGP+G+ PG GP G G Sbjct: 282 GPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNP 341 Query: 514 GPRGFPGLKGSKGSFGTG------GPRGQPGPKGDIGPPGPEGPPGSP------GPSGPQ 561 G G PG KGS G+ G GPRG PGP+G GP GP+G G P G GP+ Sbjct: 342 GTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPK 401 Query: 562 GKPGIAGKTGSP---GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 G+PG AG G+P G+ G G +GEPG GP G PG G PG++ F Sbjct: 402 GEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGF 448 Score = 139 bits (351), Expect = 6e-33 Identities = 75/159 (47%), Positives = 84/159 (52%), Gaps = 12/159 (7%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKG---DPGSLGPLGPQGPQGQPGEAGPVGERGPV 513 G GP G RGF G+ G G G +GP+G PG+ GP G GP G PG GP G +G Sbjct: 624 GLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMP 683 Query: 514 GPRGFPGL---KGSKGSFGTGGPRGQPGP------KGDIGPPGPEGPPGSPGPSGPQGKP 564 G RG G+ KG +G G GP G PG G IGPPGP G G G GP G Sbjct: 684 GERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPA 743 Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G AG G+PG+RG GP G G GPPG G PG G Q Sbjct: 744 GSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQ 782 Score = 139 bits (350), Expect = 8e-33 Identities = 73/159 (45%), Positives = 89/159 (55%), Gaps = 12/159 (7%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQG------QPGEAGPVGER 510 G PGPPGP+G +G GV G G +G G+PG G G G G + GE G G Sbjct: 516 GRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPP 575 Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPG---SPGPSGPQGKPGIA 567 GP GP G G +G+ G G G G PGP G+ G PG +G PG +PG GP+G+ G Sbjct: 576 GPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFP 635 Query: 568 GKTGSPGQRGAMGPK---GEPGIQGPPGLPGPPGPPGSQ 603 G+ GSPG +G GP+ G PG GP G GP GPPG+Q Sbjct: 636 GERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQ 674 Score = 137 bits (346), Expect = 2e-32 Identities = 79/175 (45%), Positives = 86/175 (49%), Gaps = 30/175 (17%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G GPPG RG G+ G G G GPKG PG GP G GP+G G+ G GE G G R Sbjct: 432 GPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR 491 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPG------PSGPQGKPGIAGK- 569 G G G G G GP G PG G GPPGP+G G PG P G G+PG AG+ Sbjct: 492 GLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEK 551 Query: 570 --TGSPGQRGAMGPKGEPGIQGPP---------------------GLPGPPGPPG 601 G+PG RG G GE G GPP GLPGPPGPPG Sbjct: 552 GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPG 606 Score = 137 bits (344), Expect = 4e-32 Identities = 73/153 (47%), Positives = 86/153 (56%), Gaps = 12/153 (7%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG------EAGPVGER 510 G PG G G G G G G RGP G G+ GPLGP+G G+PG E GP GE Sbjct: 345 GIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 404 Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKT 570 GP GP+G PG G +G G RG+PG G IGPPG G PG+ G G+ G+AG Sbjct: 405 GPAGPQGAPGPAGEEGK---RGARGEPGGVGPIGPPGERGAPGN---RGFPGQDGLAGPK 458 Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G+PG+RG G G G G PG PG PG PG++ Sbjct: 459 GAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR 491 Score = 136 bits (343), Expect = 5e-32 Identities = 76/172 (44%), Positives = 93/172 (54%), Gaps = 27/172 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG-- 514 G PG PG +G G G +GP G +GP+G+PG+ G GP G G PG G G +G G Sbjct: 297 GFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAP 356 Query: 515 ----------PRGFPGLKGSKGSFGTGGPRGQPGP---KGDIGP---PGPEGPPGSPGPS 558 PRG PG +G+ G G G G+PG KG+ GP PGP GP G+PGP+ Sbjct: 357 GIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA 416 Query: 559 GPQGK------PGIAGKTGSPGQRGAMGPKGEP---GIQGPPGLPGPPGPPG 601 G +GK PG G G PG+RGA G +G P G+ GP G PG GP G Sbjct: 417 GEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSG 468 Score = 136 bits (343), Expect = 5e-32 Identities = 73/157 (46%), Positives = 80/157 (50%), Gaps = 9/157 (5%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVG---------GRGPKGDPGSLGPLGPQGPQGQPGEAGP 506 +GAPG GP G G G G G RG G PG GP G GP G PGE G Sbjct: 458 KGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGR 517 Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566 G GP G RG PG+ G G G G G+ G KG G PG G PG G +G G PG Sbjct: 518 PGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP 577 Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 AG G G++GA GP G G+ GPPG PG G PG Q Sbjct: 578 AGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQ 614 Score = 135 bits (341), Expect = 8e-32 Identities = 74/152 (48%), Positives = 80/152 (52%), Gaps = 3/152 (1%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG PG RG G G GP G GP G PG G GP GPQG G+ G +G GP G Sbjct: 483 GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 542 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G PG G KG G G RG PG G+ G GP GP G G G QG PG +G G PG Sbjct: 543 GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP 602 Query: 577 GAMGPKGEPGIQGPPGLPGPP---GPPGSQSF 605 G G G+PG QG PG G P GP G + F Sbjct: 603 GPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 634 Score = 135 bits (340), Expect = 1e-31 Identities = 76/188 (40%), Positives = 93/188 (49%), Gaps = 33/188 (17%) Query: 449 LRNVTILRGAPGPPGP------RGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG 502 ++++ +G PGP GP RG +GD G KG G RG G+PG+ G GP GP G PG Sbjct: 43 IKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPG 102 Query: 503 E---------------------------AGPVGERGPVGPRGFPGLKGSKGSFGTGGPRG 535 GP+G GP GP G G G +G G G G Sbjct: 103 PPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG 162 Query: 536 QPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPG 595 +PG G +GP GP GPPG PG G GKPG AG+ G PG +GA G G PG+ G G G Sbjct: 163 EPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRG 222 Query: 596 PPGPPGSQ 603 PG G++ Sbjct: 223 YPGLDGAK 230 Score = 135 bits (339), Expect = 1e-31 Identities = 72/160 (45%), Positives = 87/160 (54%), Gaps = 15/160 (9%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G G GP G G+ G GP G +G +G PG +G GP+G G+PG+AG G G G R Sbjct: 501 GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLR 560 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G PG G G+ G GP G G +G+ G PGP G G PGP GP G+ G G G PG+ Sbjct: 561 GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA 620 Query: 577 GA---MGPKGE------------PGIQGPPGLPGPPGPPG 601 GA +GP+GE G+QGP GLPG PG G Sbjct: 621 GAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDG 660 Score = 132 bits (333), Expect = 7e-31 Identities = 74/176 (42%), Positives = 85/176 (48%), Gaps = 30/176 (17%) Query: 460 GPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFP 519 GP GP G +G G +GP G RG KG+ G+ GP G G G PG GP G GP GP G Sbjct: 48 GPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLG 107 Query: 520 G------------------LKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPG----- 556 G L +G G GPRG PGP G GP G +G PG PG Sbjct: 108 GNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVS 167 Query: 557 -------PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 P GP GKPG G+ G PG+ G GP G G +G PG PG PG G + + Sbjct: 168 GPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGY 223 Score = 132 bits (333), Expect = 7e-31 Identities = 73/158 (46%), Positives = 88/158 (55%), Gaps = 12/158 (7%) Query: 456 RGAPGP---PGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQ---GPQGQPGEAGPVGE 509 +GAPGP G RG +G+ G GP+G G +G PG+ G G GP+G PGE GP G Sbjct: 410 QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGL 469 Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQP---GPKGDIGP---PGPEGPPGSPGPSGPQGK 563 GP G G PG G G G G G+P GP+G +GP PG +G PG PGP G +G+ Sbjct: 470 AGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ 529 Query: 564 PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 PG+ G G G G G GE G+ G PGL G PG G Sbjct: 530 PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDG 567 Score = 89.0 bits (219), Expect = 1e-17 Identities = 51/114 (44%), Positives = 56/114 (49%), Gaps = 15/114 (13%) Query: 450 RNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509 R T L+G PGPPGP GD G GP G GP+G PG P GP G+ G G G Sbjct: 1064 RGFTGLQGLPGPPGP---SGDQGASGPAGPSGPRGPPG------PVGPSGKDGANGIPGP 1114 Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGK 563 GP GPR G G G GP G PGP G GPPGP + GP+ K Sbjct: 1115 IGPPGPR------GRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREK 1162 Score = 88.6 bits (218), Expect = 2e-17 Identities = 57/160 (35%), Positives = 67/160 (41%), Gaps = 65/160 (40%) Query: 496 GPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD------------- 542 GP+GQ GE G + + VGP+G PG +G P G+ GP+GD Sbjct: 32 GPKGQKGEPGDI--KDIVGPKGPPGPQG---------PAGEQGPRGDRGDKGEKGAPGPR 80 Query: 543 -----------IGPPGPEGPPGSP------------------------------GPSGPQ 561 GPPGP GPPG P GP GP+ Sbjct: 81 GRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPR 140 Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G PG AG G G +G G GEPG+ GP G GPPGPPG Sbjct: 141 GPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPG 180 Score = 85.5 bits (210), Expect = 1e-16 Identities = 42/76 (55%), Positives = 47/76 (61%), Gaps = 10/76 (13%) Query: 536 QPGPKGDIGPP-------GPEGPPGSPGPS---GPQGKPGIAGKTGSPGQRGAMGPKGEP 585 QPGPKG G P GP+GPPG GP+ GP+G G G+ G+PG RG G G P Sbjct: 30 QPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTP 89 Query: 586 GIQGPPGLPGPPGPPG 601 G GPPG PGPPGPPG Sbjct: 90 GNPGPPGPPGPPGPPG 105 Score = 70.1 bits (170), Expect = 6e-12 Identities = 33/73 (45%), Positives = 39/73 (53%), Gaps = 13/73 (17%) Query: 542 DIGPPGPEGPPGS-------------PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQ 588 D+ PGP+G G PGP GP G+ G G G G++GA GP+G G Sbjct: 27 DVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 86 Query: 589 GPPGLPGPPGPPG 601 G PG PGPPGPPG Sbjct: 87 GTPGNPGPPGPPG 99 >gi|119508426 alpha 3 type IX collagen [Homo sapiens] Length = 684 Score = 157 bits (396), Expect = 3e-38 Identities = 85/165 (51%), Positives = 95/165 (57%), Gaps = 18/165 (10%) Query: 457 GAPGPPGPRGFKGDMGVKGP---VGGRGPKGDPGSLGPLG---------PQGPQGQPGEA 504 G PGPPG GFKG G KG VG G KGDPG GP G P+G +G PG Sbjct: 181 GPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPL 240 Query: 505 GPVGERGPVG---PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQ 561 GP G+RGP+G P G PG G G G GP G GPKGD+G PGP+G PG GPSG Sbjct: 241 GPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEP 300 Query: 562 GKPGIAGKTGSPG---QRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G PG G+ G PG Q+G G G PG +GP GLPG PG GS+ Sbjct: 301 GMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSK 345 Score = 140 bits (352), Expect = 4e-33 Identities = 76/164 (46%), Positives = 89/164 (54%), Gaps = 18/164 (10%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRG---PKGDPGSLGPLGPQGPQGQPG---------E 503 +G PGPPGP G G +G++GP G RG P G PG GP+G +GP G PG E Sbjct: 210 KGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGE 269 Query: 504 AGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP------GSPGP 557 GP G RGP G G PG KG+ G G G G PG G G PG +G G+PG Sbjct: 270 RGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGE 329 Query: 558 SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 GP G PG+ G+ GS G++G G GE G GP G PG PG G Sbjct: 330 KGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAG 373 Score = 139 bits (350), Expect = 8e-33 Identities = 76/157 (48%), Positives = 86/157 (54%), Gaps = 11/157 (7%) Query: 446 GEILRNVTILR-GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEA 504 GE+L R G PGPPGP G G G G G GP G PG GP G G G+PGEA Sbjct: 17 GELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEA 76 Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564 G G PG+ G G G GP+G PG +G +GPPGP G G G GP G+ Sbjct: 77 GLPG---------LPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPG-LGGKGLPGPPGEA 126 Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G++G G G RG GP G PG+ GPPG PGPPG PG Sbjct: 127 GVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPG 163 Score = 139 bits (349), Expect = 1e-32 Identities = 74/159 (46%), Positives = 83/159 (52%), Gaps = 9/159 (5%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG---------EAGP 506 +G PGPPG G G G G G GP G PG GP GP GP G PG + Sbjct: 117 KGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPS 176 Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566 + GP GP G PG KG G G G G+ G KGD GPPGP G PGS G GP+G G+ Sbjct: 177 ICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGL 236 Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 G G PG RG +G +G PGI G PG G G G + F Sbjct: 237 PGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGF 275 Score = 137 bits (346), Expect = 2e-32 Identities = 79/188 (42%), Positives = 95/188 (50%), Gaps = 25/188 (13%) Query: 441 VDTQHGEILRNVTI-------LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPG------ 487 +D Q GE RN L G PG G +G KG+ G G +G GP G+PG Sbjct: 314 LDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAG 373 Query: 488 ------------SLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRG 535 S G LGPQGP G PG G G++G +G G PG +G +G G GP G Sbjct: 374 MPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGG 433 Query: 536 QPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPG 595 GPKGD G G +G PG G GP G G G++GS G+ G G +G G G G+PG Sbjct: 434 AAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPG 493 Query: 596 PPGPPGSQ 603 PPGP G Q Sbjct: 494 PPGPLGLQ 501 Score = 130 bits (326), Expect = 5e-30 Identities = 75/162 (46%), Positives = 83/162 (51%), Gaps = 21/162 (12%) Query: 455 LRGAPGPPGPRGFKGDMGVKG------------PVGGRGPKGDPGSLGPLGPQGPQGQPG 502 L G PGPPGP G G GV P G GP G PG GP G +G QG+ G Sbjct: 146 LPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVG 205 Query: 503 EAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQG 562 + G G+ GP GP G PG S G GPRG G G +GPPG GP G GP G G Sbjct: 206 KDGEKGDPGPPGPAGLPG------SVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPG 259 Query: 563 KPGIAGKTGSPGQRGAMGPKGE---PGIQGPPGLPGPPGPPG 601 PG AG G G G GPKG+ PG +G PG+ GP G PG Sbjct: 260 APGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPG 301 Score = 130 bits (326), Expect = 5e-30 Identities = 68/145 (46%), Positives = 77/145 (53%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G G PG RG G G G +G +GP G PG G G +G G PG GP G RG VG R Sbjct: 370 GDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDR 429 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G G G KG G G G PG KG++GP G GP G G G G G G G+ G + Sbjct: 430 GPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQ 489 Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPG 601 G GP G G+QG PG+PG G PG Sbjct: 490 GVPGPPGPLGLQGVPGVPGITGKPG 514 Score = 125 bits (314), Expect = 1e-28 Identities = 76/189 (40%), Positives = 86/189 (45%), Gaps = 43/189 (22%) Query: 456 RGAPGPPGPRGFKGD------------MGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE 503 +G PG PG RGF+G G++G VG RGP G G G G G G PG+ Sbjct: 393 QGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGD 452 Query: 504 AGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGK 563 G +G G VGP+G G +G G GT GP G G +G GPPGP G G PG G GK Sbjct: 453 KGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGK 512 Query: 564 PGIAGKTGS----------------------------PGQRGAMGPKGEPGIQGPPGL-- 593 PG+ GK S PG G GP G PG GPPG Sbjct: 513 PGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIG 572 Query: 594 -PGPPGPPG 601 PG GPPG Sbjct: 573 HPGARGPPG 581 Score = 124 bits (311), Expect = 3e-28 Identities = 72/163 (44%), Positives = 78/163 (47%), Gaps = 19/163 (11%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PGPPGP+G G G G G G G G G GP GP+G PGE G +G GP G Sbjct: 56 GLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLG 115 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI---------- 566 G GL G G G GP G G +G GP G G PG PGP GP G PG+ Sbjct: 116 G-KGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQC 174 Query: 567 --------AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G PG +G G KGE G G G G PGPPG Sbjct: 175 PSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPG 217 Score = 124 bits (311), Expect = 3e-28 Identities = 82/237 (34%), Positives = 93/237 (39%), Gaps = 92/237 (38%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPG----------------------------- 487 G PG PGP+G +GD+G +GP G GPKGD G Sbjct: 412 GDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSR 471 Query: 488 -SLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKG----------------------- 523 LGP G QGP G G G G GP+G +G PG+ G Sbjct: 472 GELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGG 531 Query: 524 --------------------SKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGK 563 S G G GP G PGP G IG PG GPPG GP+G G Sbjct: 532 MISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGD 591 Query: 564 PGIAGKTGSPGQRGAM-----GPKGEPGIQGP--------------PGLPGPPGPPG 601 PG G G G +GA GP+G+ G QGP PG PGPPG PG Sbjct: 592 PGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPG 648 Score = 120 bits (300), Expect = 5e-27 Identities = 68/157 (43%), Positives = 81/157 (51%), Gaps = 18/157 (11%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G G PG G KG+ G G G +GP G PG G G +G +G+ G AG +GE GP G Sbjct: 307 GQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEP 366 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G P G G G RG+ G +G G GP+GPPG+PG G QG+ G G G PG + Sbjct: 367 GVP------GDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQ 420 Query: 577 ------------GAMGPKGEPGIQGPPGLPGPPGPPG 601 GA GPKG+ GI G GLPG G G Sbjct: 421 GLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELG 457 Score = 117 bits (294), Expect = 2e-26 Identities = 72/180 (40%), Positives = 80/180 (44%), Gaps = 40/180 (22%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGD----------------------------- 485 ++G PGPPGP G +G GV G G G G Sbjct: 488 VQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKP 547 Query: 486 --PGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDI 543 PGS+G GP GP G PG G +G G GP PG +G G G GPRG G +GD Sbjct: 548 LAPGSIGRPGPAGPPGPPGPPGSIGHPGARGP---PGYRGPTGELGDPGPRGNQGDRGDK 604 Query: 544 GPPGP--EGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G +GP G GP GPQG PG T GQ GA G G PG G PG G G PG Sbjct: 605 GAAGAGLDGPEGDQGPQGPQGVPG----TSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660 Score = 100 bits (248), Expect = 5e-21 Identities = 57/132 (43%), Positives = 66/132 (50%), Gaps = 19/132 (14%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG-----PVGERG 511 G PGPPGP G G G +GP G RGP G+ G GP G QG +G G AG P G++G Sbjct: 560 GPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQG 619 Query: 512 PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTG 571 P GP+G PG + G G G PGP G PG PG G QG PGI + Sbjct: 620 PQGPQGVPGTS-------------KDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSA 666 Query: 572 SPGQ-RGAMGPK 582 G G +G K Sbjct: 667 CQGAVLGGVGEK 678 Score = 99.0 bits (245), Expect = 1e-20 Identities = 60/131 (45%), Positives = 70/131 (53%), Gaps = 20/131 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G+ G PGP G P G GP PGS+G G +GP PG GP GE G GPR Sbjct: 551 GSIGRPGPAG---------PPGPPGP---PGSIGHPGARGP---PGYRGPTGELGDPGPR 595 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G G +G KG+ G G GP+GD GP GP+G PG+ G G PG G G PG Sbjct: 596 GNQGDRGDKGAAGA----GLDGPEGDQGPQGPQGVPGT-SKDGQDGAPGEPGPPGDPGLP 650 Query: 577 GAMGPKGEPGI 587 GA+G +G PGI Sbjct: 651 GAIGAQGTPGI 661 Score = 51.6 bits (122), Expect = 2e-06 Identities = 26/53 (49%), Positives = 27/53 (50%), Gaps = 15/53 (28%) Query: 550 GPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G PG PGP GP GKPG G G G PPGLPGPPGP G+ Sbjct: 29 GLPGPPGPPGPPGKPGQDGIDGEAG---------------PPGLPGPPGPKGA 66 >gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo sapiens] Length = 1650 Score = 156 bits (395), Expect = 5e-38 Identities = 79/146 (54%), Positives = 89/146 (60%), Gaps = 9/146 (6%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG PGPPGP G+ G+ G G G KGDP GP G G G G G GERG G Sbjct: 856 RGHPGPPGP---PGEQGLPGTAGKEGTKGDP---GPPGAPGKDGPAGLRGFPGERGLPGT 909 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 G PGLKG++G G GP G PG +G G GP GPPG PGP GP PG AG+ G PG+ Sbjct: 910 AGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP---PGAAGEKGVPGE 966 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPG 601 +G +GP G G+QGP GLPGP GPPG Sbjct: 967 KGPIGPTGRDGVQGPVGLPGPAGPPG 992 Score = 150 bits (380), Expect = 2e-36 Identities = 84/187 (44%), Positives = 96/187 (51%), Gaps = 45/187 (24%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLG------PLGPQGP------------- 497 G PGP G RG G G +G GG+G KGDPG++G P+GP GP Sbjct: 1226 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLP 1285 Query: 498 -----QGQPGEAGPVGERGPVGPRGFPGLKGSKGS---------FGTGGPRGQPGPKGDI 543 QG+PG G G GPVGP G PGL+G G+ G GP G+ G KGD Sbjct: 1286 GSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDR 1345 Query: 544 GPPGPEGPPGSP------------GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPP 591 G PGP+G PG GP GP G PG AG G+ G G GPKGE G+QGPP Sbjct: 1346 GLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPP 1405 Query: 592 GLPGPPG 598 G PGPPG Sbjct: 1406 GHPGPPG 1412 Score = 149 bits (376), Expect = 7e-36 Identities = 85/174 (48%), Positives = 99/174 (56%), Gaps = 27/174 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGPVG--GR-GPKGD---PGSLGPLGPQGPQGQPGEAGPVGER 510 G PGPPG G KG +GV G G GR GPKG PG G G +G +G G++GP GER Sbjct: 695 GDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER 754 Query: 511 GPVGPRGFPGLKGS---KGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA 567 GP GPRG G +G+ G+ GT G G GP G+ G PGP+GP G PGP GP G PG Sbjct: 755 GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKD 814 Query: 568 GKTGSPGQRGAMGPKGEPGIQGPPGL------------------PGPPGPPGSQ 603 G G PGQRG +G +G+ G GPPG+ PGPPGPPG Q Sbjct: 815 GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ 868 Score = 149 bits (375), Expect = 9e-36 Identities = 82/171 (47%), Positives = 95/171 (55%), Gaps = 24/171 (14%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGG------RGPKGDPGSLGPLGPQGPQGQPGEAGPVGER 510 G PGP GP G G+ G KG VG +G KG+ G GP GP GP GQPG AG GE Sbjct: 983 GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEP 1042 Query: 511 GPVGPRGFPGLKGSKGSFGTGGP------RGQPGPKG------DIGPPGPEGPPGSPGPS 558 G GP+G G KG +G+ G GP +G PGP G D+GP GP GPPG GP+ Sbjct: 1043 GARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPA 1102 Query: 559 ------GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 GPQG PG G G PG++G G G PGIQG PG+ GP G G + Sbjct: 1103 GPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEK 1153 Score = 148 bits (373), Expect = 2e-35 Identities = 72/148 (48%), Positives = 84/148 (56%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L+G PGP G +G GD+G GP G GP+G G G GPQGP G G GP GE+G G Sbjct: 1071 LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1130 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574 G PG++G G G G RG+ G G G PGP GP G G GP+G PG G G PG Sbjct: 1131 ESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPG 1190 Query: 575 QRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G GP+G+ G +G G G PG PGS Sbjct: 1191 PPGEGGPRGQDGAKGDRGEDGEPGQPGS 1218 Score = 147 bits (372), Expect = 2e-35 Identities = 79/152 (51%), Positives = 89/152 (58%), Gaps = 12/152 (7%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +G PG G G +G+ GVKGP G RG KG+ G G GP GP+G G+ GP G GPVG Sbjct: 1126 KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG- 1184 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS------GPQGKPGIAGK 569 FPG G G GGPRGQ G KGD G G G PGSPGP+ GP GK G AG Sbjct: 1185 --FPGDPGPPGE---GGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1239 Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 GS G++G G KG+PG G PG GP GP G Sbjct: 1240 PGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAG 1271 Score = 145 bits (367), Expect = 8e-35 Identities = 75/153 (49%), Positives = 90/153 (58%), Gaps = 9/153 (5%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG PG +G +GD G +G G P G+ G G G GP+G PGE+GP G GP GP Sbjct: 476 GLPGLPGEKGHRGDTGAQGLPG---PPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPP 532 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS---PGPS---GPQGKPGIAGKT 570 G PG G +G G GP+G GP+G+ GPPG +G PG+ PGP GP G+ G GK Sbjct: 533 GIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKP 592 Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G PG G+ GP G PG +GPPG G GP G Q Sbjct: 593 GLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQ 625 Score = 145 bits (367), Expect = 8e-35 Identities = 76/150 (50%), Positives = 86/150 (57%), Gaps = 9/150 (6%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG---ERGPV 513 G PGPPGPRG GP G GP+G PG +G LGP G +G+PGE+G G E G Sbjct: 1091 GPPGPPGPRG------PAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVK 1144 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 GPRG G KG G G GP G GP GD GP G GP G PG GP G+ G G+ G+ Sbjct: 1145 GPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAK 1204 Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G RG G G+PG GP G GPPGP G + Sbjct: 1205 GDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1234 Score = 145 bits (366), Expect = 1e-34 Identities = 81/160 (50%), Positives = 88/160 (55%), Gaps = 12/160 (7%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP--- 512 RG G G RG GD GVKG G G G PG G G G QG PG G GERG Sbjct: 451 RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGE 510 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSG---PQGKPGIAGK 569 +GPRG PG G +G G GP G PGP G G GP+GP GS GP G P G+ G G Sbjct: 511 IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT 570 Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPG------PPGPPGSQ 603 G PG +GA+GP GE G QG PGLPG PPG PG + Sbjct: 571 QGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKE 610 Score = 145 bits (366), Expect = 1e-34 Identities = 76/152 (50%), Positives = 89/152 (58%), Gaps = 9/152 (5%) Query: 457 GAPGPPGP---RGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPV 513 GAPG GP RGF G+ G+ G GG G KG+ G P GP GP G PGE G G GP+ Sbjct: 887 GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEG---PSGPPGPAGSPGERGAAGSGGPI 943 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQG---KPGIAGKT 570 GP G PG +G G+ G G G+ GP G G G +GP G PGP+GP G + G G+ Sbjct: 944 GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 1003 Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G PGQ+G G KGE G GPPG GP G PG+ Sbjct: 1004 GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1035 Score = 144 bits (363), Expect = 2e-34 Identities = 76/160 (47%), Positives = 89/160 (55%), Gaps = 18/160 (11%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GA G PG RG +G G KG G RG G PG +G G GP G+ GE G VG GP GP Sbjct: 1037 GADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP- 1095 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI---------A 567 PG +G G G GP+G PG G++GPPG +G PG G G QG+PG+ Sbjct: 1096 --PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEK 1153 Query: 568 GKTGSPGQRGAMGPKGEPGIQGPPGLPGP------PGPPG 601 G++G PG+ G GPKG G GP G PGP PGPPG Sbjct: 1154 GESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG 1193 Score = 142 bits (359), Expect = 7e-34 Identities = 77/167 (46%), Positives = 91/167 (54%), Gaps = 18/167 (10%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGPVG 508 L G G PG +G +G G GP G G +G GS GP+GP QGP G GE G G Sbjct: 906 LPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPG 965 Query: 509 ERGPVGPRGFPGLKGSKGSFGTGGP---RGQPGPKGDIGPPGPE---------GPPGSPG 556 E+GP+GP G G++G G G GP G+ G KG++G PG + GPPG PG Sbjct: 966 EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG 1025 Query: 557 PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 P GP G+PG AG G PG RG G G G +G G GPPGP G Q Sbjct: 1026 PIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ 1072 Score = 142 bits (359), Expect = 7e-34 Identities = 74/150 (49%), Positives = 88/150 (58%), Gaps = 6/150 (4%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG PG G G+ G GP+G RGP G PGS G G +G +G PG G G+ GPVGP Sbjct: 1211 GEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPA 1270 Query: 517 G---FPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 G PG G +G G+ G +G+PG G GPPGP GPPG PG +G G G+ G P Sbjct: 1271 GPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGL---RGDAGAKGEKGHP 1327 Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G G +GP GE G +G GLPGP G PG + Sbjct: 1328 GLIGLIGPPGEQGEKGDRGLPGPQGSPGQK 1357 Score = 141 bits (356), Expect = 2e-33 Identities = 77/152 (50%), Positives = 86/152 (56%), Gaps = 9/152 (5%) Query: 460 GPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQ---GQPGEAGPVGERGPVGPR 516 GPPGP G+ G G G G G KG+ G LGP GP+GPQ G PG+AG G G G R Sbjct: 401 GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGAR 460 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ- 575 G PG G KG G G G PG KG G G +G PG PG G +G G G G PG+ Sbjct: 461 GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 520 Query: 576 --RGAMGPKGEPGIQGPP---GLPGPPGPPGS 602 RG +GPKG PGI GPP G+ GP GP GS Sbjct: 521 GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGS 552 Score = 140 bits (353), Expect = 3e-33 Identities = 81/167 (48%), Positives = 87/167 (52%), Gaps = 21/167 (12%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGP--- 506 RGA G GP G G G +GP G G KG PG GP+GP QGP G PG AGP Sbjct: 934 RGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGV 993 Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566 GE G G G PG KG+KG+ G GP G PGP G +G PG G G PG GPQG G Sbjct: 994 AGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGA 1053 Query: 567 AGKTGSPGQRGAMGP------------KGEPGIQGPPGLPGPPGPPG 601 G G+ G G GP KGE G GP G PGPPGP G Sbjct: 1054 KGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG 1100 Score = 140 bits (353), Expect = 3e-33 Identities = 78/165 (47%), Positives = 86/165 (52%), Gaps = 21/165 (12%) Query: 457 GAPGPPGPRGFKGDMGVKG------------PVGGRGPKGDPGSLGPLGPQGPQGQPGEA 504 G PGPPGP+G GD G KG P G GP+G G+ G G G GQPG Sbjct: 1160 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSP 1219 Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG------PEGPPGSPGPS 558 GP GE GP GP G G GS GS G G +G G G IG PG P GP G PGP Sbjct: 1220 GPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPD 1279 Query: 559 GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G +G PG G+ G PG G GP PG GPPGLPG G G++ Sbjct: 1280 GLRGLPGSVGQQGRPGATGQAGP---PGPVGPPGLPGLRGDAGAK 1321 Score = 140 bits (352), Expect = 4e-33 Identities = 76/174 (43%), Positives = 86/174 (49%), Gaps = 27/174 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PGPPG RG G G KG +G +G G PG G G QG G G GP GE+GP G Sbjct: 533 GIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKP 592 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI---------- 566 G PG+ GS G G G G PG KG+ GP GP+GP G PGP G +G GI Sbjct: 593 GLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEK 652 Query: 567 -----------------AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G+ G PG RG GP+G G GP G PGPPG G + Sbjct: 653 GEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEK 706 Score = 140 bits (352), Expect = 4e-33 Identities = 79/173 (45%), Positives = 84/173 (48%), Gaps = 27/173 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G G GPRG G G KG GG GP G PG G GPQGP G PG GP G G G Sbjct: 758 GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLP 817 Query: 517 GFPGLKGSKGSFGTGGPRGQP------------GPKGDIGPPGPEGPP------------ 552 G PG +G G G GP G P GP G+ G PGP GPP Sbjct: 818 GHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKE 877 Query: 553 ---GSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G PGP G GK G AG G PG+RG G G PG++G G GPPGP GS Sbjct: 878 GTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGS 930 Score = 138 bits (348), Expect = 1e-32 Identities = 78/174 (44%), Positives = 91/174 (52%), Gaps = 24/174 (13%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGG------RGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509 +G PGPPG +G G G+ GP G +GP+G PG G G GP G PG+ GP G Sbjct: 556 QGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGT 615 Query: 510 RG------PVGPRGFP---------GLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP--- 551 +G P GP G+P G++G KG G G G PG KGDIG G G Sbjct: 616 KGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV 675 Query: 552 PGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 PGS G GP+G G G TG PG G MG KG+ G+ G PG PG GP GS F Sbjct: 676 PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGF 729 Score = 137 bits (346), Expect = 2e-32 Identities = 79/166 (47%), Positives = 88/166 (53%), Gaps = 18/166 (10%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG---------EAGP 506 +G PG GP G G GV+GPVG GP G PG G G +G G PG E GP Sbjct: 961 KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 1020 Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD------IGPPGPEGPPGSPGPSGP 560 G GP+GP G PG G+ G G GP+G G KGD GPPGP G G PGPSG Sbjct: 1021 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1080 Query: 561 QGKPGIA---GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 +G+ G G G PG RG GP G G QGPPG G GPPG + Sbjct: 1081 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEK 1126 Score = 137 bits (345), Expect = 3e-32 Identities = 76/155 (49%), Positives = 84/155 (54%), Gaps = 15/155 (9%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG G GPRG +G G +G G RG G G+ G G GP G PGE G G P GP Sbjct: 742 RGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPG---PQGP 798 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 GFPG KG G G G G PG +G++G G GPPG PG GPQ G AG+TG G+ Sbjct: 799 NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ---GAAGETGPMGE 855 Query: 576 RGAMGPKGEPGIQGPPGL---------PGPPGPPG 601 RG GP G PG QG PG PGPPG PG Sbjct: 856 RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG 890 Score = 136 bits (342), Expect = 6e-32 Identities = 74/171 (43%), Positives = 87/171 (50%), Gaps = 15/171 (8%) Query: 450 RNVTILRGAPGPPG------------PRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGP 497 R T +G PGPPG PRG G+ G +G +G +GP G PG G G GP Sbjct: 487 RGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGP 546 Query: 498 QGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD---IGPPGPEGPPGS 554 QG G GP GE GP G +G PG +G G G GP G+ GP+G G PG +GPPG Sbjct: 547 QGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 606 Query: 555 PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 PG GP G G G +G G G GP+G G+ G GL G G G F Sbjct: 607 PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF 657 Score = 135 bits (340), Expect = 1e-31 Identities = 89/223 (39%), Positives = 101/223 (45%), Gaps = 61/223 (27%) Query: 440 AVDTQHGEILRNVTI-LRGAPGP------------PGPRGFKGDMGVKGPVGGRGPK--- 483 A + Q IL+ + LRG PGP PG G KG+ G GP G RGP+ Sbjct: 383 AQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLT 442 Query: 484 ---------------------GDP------------------GSLGPLGPQGPQGQPGEA 504 GDP G G G QG G PGE Sbjct: 443 GPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED 502 Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS---GPQ 561 G G+ G +GPRG PG G +G G GP G PGP G G GP+GP GS GP GP Sbjct: 503 GERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP 562 Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP---GPPG 601 G+ G G G PG +GA+GP GE G QG PGLPG P GPPG Sbjct: 563 GQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPG 605 Score = 135 bits (340), Expect = 1e-31 Identities = 74/167 (44%), Positives = 87/167 (52%), Gaps = 21/167 (12%) Query: 456 RGAPGPPGPRGFKGDMGVKG------------------PVGGRGPKGDPGSLGPLGPQGP 497 +G G G GFKGD+GVKG P G GP GDPG G +G +G Sbjct: 649 KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 708 Query: 498 QGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEG---PPGS 554 G PG G G +GP G GFPG G+ G G G G+ GP+G+ GP GP G P G+ Sbjct: 709 LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 768 Query: 555 PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G SG +G G G G PG+RG GP+G G GP G PGPPG G Sbjct: 769 TGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDG 815 Score = 133 bits (335), Expect = 4e-31 Identities = 72/162 (44%), Positives = 82/162 (50%), Gaps = 15/162 (9%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG----- 511 G GPPGP G G+ G G G GP G PG GP G G +G PGE GP+G G Sbjct: 920 GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 979 Query: 512 -------PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEG---PPGSPGPSGPQ 561 P GP G G G KG G G +G G KG+ GPPGP G P G PG +G Sbjct: 980 GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGAD 1039 Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G+PG G G G +G G +G G GP GL G PGP G + Sbjct: 1040 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEK 1081 Score = 132 bits (333), Expect = 7e-31 Identities = 76/161 (47%), Positives = 87/161 (54%), Gaps = 18/161 (11%) Query: 455 LRGAPGPPGPRGFKGDMGVKG------PVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG 508 ++G PG GPRG +G+ G G P G +GP GD GP G GP G PG+ GP G Sbjct: 1137 IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD---GPKGNPGPVGFPGDPGPPG 1193 Query: 509 ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP---EGPPGSPGPSGPQGKPG 565 E GPRG G KG +G G G G PGP G+ GPPGP GP GSPG G QG G Sbjct: 1194 EG---GPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKG 1250 Query: 566 I---AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G G+PG+ G +GP G G GP GL G PG G Q Sbjct: 1251 AKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQ 1291 Score = 129 bits (323), Expect = 1e-29 Identities = 76/157 (48%), Positives = 82/157 (52%), Gaps = 9/157 (5%) Query: 456 RGAPGPPGPRGF---KGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 RG PG GPRG KG G+ GP G RG G G G LGPQG G PG+ G G +G Sbjct: 514 RGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGL 573 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP---GSPGPSGPQGK---PGI 566 GP+G G G KG G G G PG G G PG EGPP G+ GPSGPQG PG Sbjct: 574 PGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGP 633 Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G G G RG G KGE G G PG G G G + Sbjct: 634 RGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDR 670 Score = 127 bits (318), Expect = 4e-29 Identities = 76/185 (41%), Positives = 89/185 (48%), Gaps = 39/185 (21%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPVGERGP 512 +G G PGPRG KG G++G G +G KG+ PG G +G +G +G+ G G GE GP Sbjct: 625 QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGP 684 Query: 513 VGPRGF---------PGLKGSKGSFGTGGPRGQPG---PKGDIGPP-------------- 546 GP+G PGL G KG G G G PG PKG +G P Sbjct: 685 EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 744 Query: 547 ----------GPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGP 596 GP GP G GP G GK G G +G G G G +G PG QGP G PGP Sbjct: 745 SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 804 Query: 597 PGPPG 601 GPPG Sbjct: 805 KGPPG 809 Score = 124 bits (310), Expect = 3e-28 Identities = 68/150 (45%), Positives = 76/150 (50%), Gaps = 3/150 (2%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L G PG GP G G G G G +GP G G LG GP+G +G G G G +G G Sbjct: 594 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 653 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPE---GPPGSPGPSGPQGKPGIAGKTG 571 GFPG KG G G G G PG +G+ GP GP+ GP G PGP G G+ G G G Sbjct: 654 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 713 Query: 572 SPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 PG G GPKG G G PG G G G Sbjct: 714 LPGYPGRQGPKGSLGFPGFPGASGEKGARG 743 Score = 120 bits (300), Expect = 5e-27 Identities = 69/163 (42%), Positives = 88/163 (53%), Gaps = 18/163 (11%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG-- 514 G GPPG +G +G G +GP+G GP+G G G G +G +G+ GE G G +G +G Sbjct: 608 GKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVK 667 Query: 515 -PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------PGSPGPSGPQGK- 563 RG G+ GS+G G GP+G+ GP GD GPPG G PG PG GP+G Sbjct: 668 GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL 727 Query: 564 -----PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 PG +G+ G+ G G GP+GE G GP G GP G G Sbjct: 728 GFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATG 770 Score = 114 bits (285), Expect = 3e-25 Identities = 73/200 (36%), Positives = 84/200 (42%), Gaps = 49/200 (24%) Query: 448 ILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV 507 +L ++ G PGP GP G G G++ G GP GDPG GP G G G G GP Sbjct: 304 VLEPGMLVEGPPGPEGPAGLIGPPGIQ---GNPGPVGDPGERGPPGRAGLPGSDGAPGPP 360 Query: 508 --------------GERGPV--------------------GPRGFPGLKGSKGSFGTGGP 533 G++GPV GP G G G G G G Sbjct: 361 GTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGS 420 Query: 534 RGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGL 593 G G GD+GP GP GP G GP G G+ G AG G+ G G G KG+ G G PGL Sbjct: 421 PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGL 480 Query: 594 PGP------------PGPPG 601 PG PGPPG Sbjct: 481 PGEKGHRGDTGAQGLPGPPG 500 Score = 111 bits (277), Expect = 2e-24 Identities = 74/189 (39%), Positives = 84/189 (44%), Gaps = 44/189 (23%) Query: 458 APGPPGPRGFKGDMGVKGP-VGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 A GP G +G KG+ V P + GP G G G +GP G QG PG G GERGP G Sbjct: 289 AHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA 348 Query: 517 GFPGLKGSKGS----------FGTGGP------------------------RGQPGPKGD 542 G PG G+ G FG+GG RG PGP G Sbjct: 349 GLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGY 408 Query: 543 IGPPGPEGPPGSPGPSG------PQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGP 596 G PGP G PGSPG G PQG G G TG PG+ G +G G G G+PG Sbjct: 409 TGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGR---RGRAGADGARGMPGD 465 Query: 597 PGPPGSQSF 605 PG G + F Sbjct: 466 PGVKGDRGF 474 Score = 92.8 bits (229), Expect = 8e-19 Identities = 48/97 (49%), Positives = 56/97 (57%), Gaps = 9/97 (9%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPVGERG 511 L G GPPG +G KGD G+ GP G G KG+ PG+ GP+GP GP G PG AGP G +G Sbjct: 1329 LIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKG 1388 Query: 512 PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548 GP G KG G GP G PGP G++ P P Sbjct: 1389 ATGP------GGPKGEKGVQGPPGHPGPPGEVIQPLP 1419 Score = 72.4 bits (176), Expect = 1e-12 Identities = 49/126 (38%), Positives = 56/126 (44%), Gaps = 17/126 (13%) Query: 480 RGPKGDPGSLGPLGPQGPQGQ---PGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQ 536 R P+ P L Q PQ Q PGE + E + P GPRG Sbjct: 246 RSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPL----------EEAAHGPRGL 295 Query: 537 PGPKGD--IGPPGP--EGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPG 592 G KG+ + PG EGPPG GP+G G PGI G G G G GP G G+ G G Sbjct: 296 KGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDG 355 Query: 593 LPGPPG 598 PGPPG Sbjct: 356 APGPPG 361 >gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo sapiens] Length = 1629 Score = 156 bits (395), Expect = 5e-38 Identities = 79/146 (54%), Positives = 89/146 (60%), Gaps = 9/146 (6%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG PGPPGP G+ G+ G G G KGDPG G G GP G G G ERG G Sbjct: 835 RGHPGPPGP---PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG---ERGLPGT 888 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 G PGLKG++G G GP G PG +G G GP GPPG PGP GP PG AG+ G PG+ Sbjct: 889 AGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP---PGAAGEKGVPGE 945 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPG 601 +G +GP G G+QGP GLPGP GPPG Sbjct: 946 KGPIGPTGRDGVQGPVGLPGPAGPPG 971 Score = 150 bits (380), Expect = 2e-36 Identities = 84/187 (44%), Positives = 96/187 (51%), Gaps = 45/187 (24%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLG------PLGPQGP------------- 497 G PGP G RG G G +G GG+G KGDPG++G P+GP GP Sbjct: 1205 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLP 1264 Query: 498 -----QGQPGEAGPVGERGPVGPRGFPGLKGSKGS---------FGTGGPRGQPGPKGDI 543 QG+PG G G GPVGP G PGL+G G+ G GP G+ G KGD Sbjct: 1265 GSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDR 1324 Query: 544 GPPGPEGPPGSP------------GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPP 591 G PGP+G PG GP GP G PG AG G+ G G GPKGE G+QGPP Sbjct: 1325 GLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPP 1384 Query: 592 GLPGPPG 598 G PGPPG Sbjct: 1385 GHPGPPG 1391 Score = 149 bits (376), Expect = 7e-36 Identities = 85/174 (48%), Positives = 99/174 (56%), Gaps = 27/174 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGPVG--GR-GPKGD---PGSLGPLGPQGPQGQPGEAGPVGER 510 G PGPPG G KG +GV G G GR GPKG PG G G +G +G G++GP GER Sbjct: 674 GDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER 733 Query: 511 GPVGPRGFPGLKGS---KGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA 567 GP GPRG G +G+ G+ GT G G GP G+ G PGP+GP G PGP GP G PG Sbjct: 734 GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKD 793 Query: 568 GKTGSPGQRGAMGPKGEPGIQGPPGL------------------PGPPGPPGSQ 603 G G PGQRG +G +G+ G GPPG+ PGPPGPPG Q Sbjct: 794 GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ 847 Score = 149 bits (375), Expect = 9e-36 Identities = 82/171 (47%), Positives = 95/171 (55%), Gaps = 24/171 (14%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGG------RGPKGDPGSLGPLGPQGPQGQPGEAGPVGER 510 G PGP GP G G+ G KG VG +G KG+ G GP GP GP GQPG AG GE Sbjct: 962 GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEP 1021 Query: 511 GPVGPRGFPGLKGSKGSFGTGGP------RGQPGPKG------DIGPPGPEGPPGSPGPS 558 G GP+G G KG +G+ G GP +G PGP G D+GP GP GPPG GP+ Sbjct: 1022 GARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPA 1081 Query: 559 ------GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 GPQG PG G G PG++G G G PGIQG PG+ GP G G + Sbjct: 1082 GPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEK 1132 Score = 148 bits (373), Expect = 2e-35 Identities = 72/148 (48%), Positives = 84/148 (56%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L+G PGP G +G GD+G GP G GP+G G G GPQGP G G GP GE+G G Sbjct: 1050 LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1109 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574 G PG++G G G G RG+ G G G PGP GP G G GP+G PG G G PG Sbjct: 1110 ESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPG 1169 Query: 575 QRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G GP+G+ G +G G G PG PGS Sbjct: 1170 PPGEGGPRGQDGAKGDRGEDGEPGQPGS 1197 Score = 147 bits (372), Expect = 2e-35 Identities = 79/152 (51%), Positives = 89/152 (58%), Gaps = 12/152 (7%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +G PG G G +G+ GVKGP G RG KG+ G G GP GP+G G+ GP G GPV Sbjct: 1105 KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPV-- 1162 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS------GPQGKPGIAGK 569 GFP G G G GGPRGQ G KGD G G G PGSPGP+ GP GK G AG Sbjct: 1163 -GFP---GDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1218 Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 GS G++G G KG+PG G PG GP GP G Sbjct: 1219 PGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAG 1250 Score = 145 bits (367), Expect = 8e-35 Identities = 75/153 (49%), Positives = 90/153 (58%), Gaps = 9/153 (5%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG PG +G +GD G +G G P G+ G G G GP+G PGE+GP G GP GP Sbjct: 455 GLPGLPGEKGHRGDTGAQGLPG---PPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPP 511 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS---PGPS---GPQGKPGIAGKT 570 G PG G +G G GP+G GP+G+ GPPG +G PG+ PGP GP G+ G GK Sbjct: 512 GIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKP 571 Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G PG G+ GP G PG +GPPG G GP G Q Sbjct: 572 GLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQ 604 Score = 145 bits (367), Expect = 8e-35 Identities = 76/150 (50%), Positives = 86/150 (57%), Gaps = 9/150 (6%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG---ERGPV 513 G PGPPGPRG GP G GP+G PG +G LGP G +G+PGE+G G E G Sbjct: 1070 GPPGPPGPRG------PAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVK 1123 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 GPRG G KG G G GP G GP GD GP G GP G PG GP G+ G G+ G+ Sbjct: 1124 GPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAK 1183 Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G RG G G+PG GP G GPPGP G + Sbjct: 1184 GDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1213 Score = 145 bits (366), Expect = 1e-34 Identities = 81/160 (50%), Positives = 88/160 (55%), Gaps = 12/160 (7%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP--- 512 RG G G RG GD GVKG G G G PG G G G QG PG G GERG Sbjct: 430 RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGE 489 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSG---PQGKPGIAGK 569 +GPRG PG G +G G GP G PGP G G GP+GP GS GP G P G+ G G Sbjct: 490 IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT 549 Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPG------PPGPPGSQ 603 G PG +GA+GP GE G QG PGLPG PPG PG + Sbjct: 550 QGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKE 589 Score = 145 bits (366), Expect = 1e-34 Identities = 76/152 (50%), Positives = 89/152 (58%), Gaps = 9/152 (5%) Query: 457 GAPGPPGP---RGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPV 513 GAPG GP RGF G+ G+ G GG G KG+ G P GP GP G PGE G G GP+ Sbjct: 866 GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEG---PSGPPGPAGSPGERGAAGSGGPI 922 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQG---KPGIAGKT 570 GP G PG +G G+ G G G+ GP G G G +GP G PGP+GP G + G G+ Sbjct: 923 GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 982 Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G PGQ+G G KGE G GPPG GP G PG+ Sbjct: 983 GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1014 Score = 144 bits (363), Expect = 2e-34 Identities = 76/160 (47%), Positives = 89/160 (55%), Gaps = 18/160 (11%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GA G PG RG +G G KG G RG G PG +G G GP G+ GE G VG GP GP Sbjct: 1016 GADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP- 1074 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI---------A 567 PG +G G G GP+G PG G++GPPG +G PG G G QG+PG+ Sbjct: 1075 --PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEK 1132 Query: 568 GKTGSPGQRGAMGPKGEPGIQGPPGLPGP------PGPPG 601 G++G PG+ G GPKG G GP G PGP PGPPG Sbjct: 1133 GESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG 1172 Score = 142 bits (359), Expect = 7e-34 Identities = 77/167 (46%), Positives = 91/167 (54%), Gaps = 18/167 (10%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGPVG 508 L G G PG +G +G G GP G G +G GS GP+GP QGP G GE G G Sbjct: 885 LPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPG 944 Query: 509 ERGPVGPRGFPGLKGSKGSFGTGGP---RGQPGPKGDIGPPGPE---------GPPGSPG 556 E+GP+GP G G++G G G GP G+ G KG++G PG + GPPG PG Sbjct: 945 EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG 1004 Query: 557 PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 P GP G+PG AG G PG RG G G G +G G GPPGP G Q Sbjct: 1005 PIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ 1051 Score = 142 bits (359), Expect = 7e-34 Identities = 74/150 (49%), Positives = 88/150 (58%), Gaps = 6/150 (4%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG PG G G+ G GP+G RGP G PGS G G +G +G PG G G+ GPVGP Sbjct: 1190 GEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPA 1249 Query: 517 G---FPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 G PG G +G G+ G +G+PG G GPPGP GPPG PG +G G G+ G P Sbjct: 1250 GPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGL---RGDAGAKGEKGHP 1306 Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G G +GP GE G +G GLPGP G PG + Sbjct: 1307 GLIGLIGPPGEQGEKGDRGLPGPQGSPGQK 1336 Score = 141 bits (356), Expect = 2e-33 Identities = 77/152 (50%), Positives = 86/152 (56%), Gaps = 9/152 (5%) Query: 460 GPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQ---GQPGEAGPVGERGPVGPR 516 GPPGP G+ G G G G G KG+ G LGP GP+GPQ G PG+AG G G G R Sbjct: 380 GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGAR 439 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ- 575 G PG G KG G G G PG KG G G +G PG PG G +G G G G PG+ Sbjct: 440 GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 499 Query: 576 --RGAMGPKGEPGIQGPP---GLPGPPGPPGS 602 RG +GPKG PGI GPP G+ GP GP GS Sbjct: 500 GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGS 531 Score = 140 bits (353), Expect = 3e-33 Identities = 81/167 (48%), Positives = 87/167 (52%), Gaps = 21/167 (12%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGP--- 506 RGA G GP G G G +GP G G KG PG GP+GP QGP G PG AGP Sbjct: 913 RGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGV 972 Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566 GE G G G PG KG+KG+ G GP G PGP G +G PG G G PG GPQG G Sbjct: 973 AGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGA 1032 Query: 567 AGKTGSPGQRGAMGP------------KGEPGIQGPPGLPGPPGPPG 601 G G+ G G GP KGE G GP G PGPPGP G Sbjct: 1033 KGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG 1079 Score = 140 bits (353), Expect = 3e-33 Identities = 78/165 (47%), Positives = 86/165 (52%), Gaps = 21/165 (12%) Query: 457 GAPGPPGPRGFKGDMGVKG------------PVGGRGPKGDPGSLGPLGPQGPQGQPGEA 504 G PGPPGP+G GD G KG P G GP+G G+ G G G GQPG Sbjct: 1139 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSP 1198 Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG------PEGPPGSPGPS 558 GP GE GP GP G G GS GS G G +G G G IG PG P GP G PGP Sbjct: 1199 GPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPD 1258 Query: 559 GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G +G PG G+ G PG G GP PG GPPGLPG G G++ Sbjct: 1259 GLRGLPGSVGQQGRPGATGQAGP---PGPVGPPGLPGLRGDAGAK 1300 Score = 140 bits (352), Expect = 4e-33 Identities = 76/174 (43%), Positives = 86/174 (49%), Gaps = 27/174 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PGPPG RG G G KG +G +G G PG G G QG G G GP GE+GP G Sbjct: 512 GIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKP 571 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI---------- 566 G PG+ GS G G G G PG KG+ GP GP+GP G PGP G +G GI Sbjct: 572 GLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEK 631 Query: 567 -----------------AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G+ G PG RG GP+G G GP G PGPPG G + Sbjct: 632 GEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEK 685 Score = 140 bits (352), Expect = 4e-33 Identities = 79/173 (45%), Positives = 84/173 (48%), Gaps = 27/173 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G G GPRG G G KG GG GP G PG G GPQGP G PG GP G G G Sbjct: 737 GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLP 796 Query: 517 GFPGLKGSKGSFGTGGPRGQP------------GPKGDIGPPGPEGPP------------ 552 G PG +G G G GP G P GP G+ G PGP GPP Sbjct: 797 GHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKE 856 Query: 553 ---GSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G PGP G GK G AG G PG+RG G G PG++G G GPPGP GS Sbjct: 857 GTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGS 909 Score = 138 bits (348), Expect = 1e-32 Identities = 78/174 (44%), Positives = 91/174 (52%), Gaps = 24/174 (13%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGG------RGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509 +G PGPPG +G G G+ GP G +GP+G PG G G GP G PG+ GP G Sbjct: 535 QGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGT 594 Query: 510 RG------PVGPRGFP---------GLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP--- 551 +G P GP G+P G++G KG G G G PG KGDIG G G Sbjct: 595 KGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV 654 Query: 552 PGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 PGS G GP+G G G TG PG G MG KG+ G+ G PG PG GP GS F Sbjct: 655 PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGF 708 Score = 137 bits (346), Expect = 2e-32 Identities = 79/166 (47%), Positives = 88/166 (53%), Gaps = 18/166 (10%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG---------EAGP 506 +G PG GP G G GV+GPVG GP G PG G G +G G PG E GP Sbjct: 940 KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 999 Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD------IGPPGPEGPPGSPGPSGP 560 G GP+GP G PG G+ G G GP+G G KGD GPPGP G G PGPSG Sbjct: 1000 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1059 Query: 561 QGKPGIA---GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 +G+ G G G PG RG GP G G QGPPG G GPPG + Sbjct: 1060 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEK 1105 Score = 137 bits (345), Expect = 3e-32 Identities = 76/155 (49%), Positives = 84/155 (54%), Gaps = 15/155 (9%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG G GPRG +G G +G G RG G G+ G G GP G PGE G G P GP Sbjct: 721 RGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPG---PQGP 777 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 GFPG KG G G G G PG +G++G G GPPG PG GPQ G AG+TG G+ Sbjct: 778 NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ---GAAGETGPMGE 834 Query: 576 RGAMGPKGEPGIQGPPGL---------PGPPGPPG 601 RG GP G PG QG PG PGPPG PG Sbjct: 835 RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG 869 Score = 136 bits (342), Expect = 6e-32 Identities = 74/171 (43%), Positives = 87/171 (50%), Gaps = 15/171 (8%) Query: 450 RNVTILRGAPGPPG------------PRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGP 497 R T +G PGPPG PRG G+ G +G +G +GP G PG G G GP Sbjct: 466 RGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGP 525 Query: 498 QGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD---IGPPGPEGPPGS 554 QG G GP GE GP G +G PG +G G G GP G+ GP+G G PG +GPPG Sbjct: 526 QGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 585 Query: 555 PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 PG GP G G G +G G G GP+G G+ G GL G G G F Sbjct: 586 PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF 636 Score = 135 bits (340), Expect = 1e-31 Identities = 89/223 (39%), Positives = 101/223 (45%), Gaps = 61/223 (27%) Query: 440 AVDTQHGEILRNVTI-LRGAPGP------------PGPRGFKGDMGVKGPVGGRGPK--- 483 A + Q IL+ + LRG PGP PG G KG+ G GP G RGP+ Sbjct: 362 AQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLT 421 Query: 484 ---------------------GDP------------------GSLGPLGPQGPQGQPGEA 504 GDP G G G QG G PGE Sbjct: 422 GPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED 481 Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS---GPQ 561 G G+ G +GPRG PG G +G G GP G PGP G G GP+GP GS GP GP Sbjct: 482 GERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP 541 Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP---GPPG 601 G+ G G G PG +GA+GP GE G QG PGLPG P GPPG Sbjct: 542 GQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPG 584 Score = 135 bits (340), Expect = 1e-31 Identities = 74/167 (44%), Positives = 87/167 (52%), Gaps = 21/167 (12%) Query: 456 RGAPGPPGPRGFKGDMGVKG------------------PVGGRGPKGDPGSLGPLGPQGP 497 +G G G GFKGD+GVKG P G GP GDPG G +G +G Sbjct: 628 KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 687 Query: 498 QGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEG---PPGS 554 G PG G G +GP G GFPG G+ G G G G+ GP+G+ GP GP G P G+ Sbjct: 688 LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 747 Query: 555 PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G SG +G G G G PG+RG GP+G G GP G PGPPG G Sbjct: 748 TGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDG 794 Score = 133 bits (335), Expect = 4e-31 Identities = 72/162 (44%), Positives = 82/162 (50%), Gaps = 15/162 (9%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG----- 511 G GPPGP G G+ G G G GP G PG GP G G +G PGE GP+G G Sbjct: 899 GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 958 Query: 512 -------PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEG---PPGSPGPSGPQ 561 P GP G G G KG G G +G G KG+ GPPGP G P G PG +G Sbjct: 959 GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGAD 1018 Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G+PG G G G +G G +G G GP GL G PGP G + Sbjct: 1019 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEK 1060 Score = 132 bits (333), Expect = 7e-31 Identities = 76/161 (47%), Positives = 87/161 (54%), Gaps = 18/161 (11%) Query: 455 LRGAPGPPGPRGFKGDMGVKG------PVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG 508 ++G PG GPRG +G+ G G P G +GP GD GP G GP G PG+ GP G Sbjct: 1116 IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD---GPKGNPGPVGFPGDPGPPG 1172 Query: 509 ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP---EGPPGSPGPSGPQGKPG 565 E GPRG G KG +G G G G PGP G+ GPPGP GP GSPG G QG G Sbjct: 1173 EG---GPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKG 1229 Query: 566 I---AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G G+PG+ G +GP G G GP GL G PG G Q Sbjct: 1230 AKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQ 1270 Score = 129 bits (323), Expect = 1e-29 Identities = 76/157 (48%), Positives = 82/157 (52%), Gaps = 9/157 (5%) Query: 456 RGAPGPPGPRGF---KGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 RG PG GPRG KG G+ GP G RG G G G LGPQG G PG+ G G +G Sbjct: 493 RGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGL 552 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP---GSPGPSGPQGK---PGI 566 GP+G G G KG G G G PG G G PG EGPP G+ GPSGPQG PG Sbjct: 553 PGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGP 612 Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G G G RG G KGE G G PG G G G + Sbjct: 613 RGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDR 649 Score = 127 bits (318), Expect = 4e-29 Identities = 76/185 (41%), Positives = 89/185 (48%), Gaps = 39/185 (21%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPVGERGP 512 +G G PGPRG KG G++G G +G KG+ PG G +G +G +G+ G G GE GP Sbjct: 604 QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGP 663 Query: 513 VGPRGF---------PGLKGSKGSFGTGGPRGQPG---PKGDIGPP-------------- 546 GP+G PGL G KG G G G PG PKG +G P Sbjct: 664 EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 723 Query: 547 ----------GPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGP 596 GP GP G GP G GK G G +G G G G +G PG QGP G PGP Sbjct: 724 SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 783 Query: 597 PGPPG 601 GPPG Sbjct: 784 KGPPG 788 Score = 124 bits (310), Expect = 3e-28 Identities = 68/150 (45%), Positives = 76/150 (50%), Gaps = 3/150 (2%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L G PG GP G G G G G +GP G G LG GP+G +G G G G +G G Sbjct: 573 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 632 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPE---GPPGSPGPSGPQGKPGIAGKTG 571 GFPG KG G G G G PG +G+ GP GP+ GP G PGP G G+ G G G Sbjct: 633 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 692 Query: 572 SPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 PG G GPKG G G PG G G G Sbjct: 693 LPGYPGRQGPKGSLGFPGFPGASGEKGARG 722 Score = 120 bits (300), Expect = 5e-27 Identities = 69/163 (42%), Positives = 88/163 (53%), Gaps = 18/163 (11%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG-- 514 G GPPG +G +G G +GP+G GP+G G G G +G +G+ GE G G +G +G Sbjct: 587 GKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVK 646 Query: 515 -PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------PGSPGPSGPQGK- 563 RG G+ GS+G G GP+G+ GP GD GPPG G PG PG GP+G Sbjct: 647 GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL 706 Query: 564 -----PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 PG +G+ G+ G G GP+GE G GP G GP G G Sbjct: 707 GFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATG 749 Score = 114 bits (285), Expect = 3e-25 Identities = 73/200 (36%), Positives = 84/200 (42%), Gaps = 49/200 (24%) Query: 448 ILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV 507 +L ++ G PGP GP G G G++ G GP GDPG GP G G G G GP Sbjct: 283 VLEPGMLVEGPPGPEGPAGLIGPPGIQ---GNPGPVGDPGERGPPGRAGLPGSDGAPGPP 339 Query: 508 --------------GERGPV--------------------GPRGFPGLKGSKGSFGTGGP 533 G++GPV GP G G G G G G Sbjct: 340 GTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGS 399 Query: 534 RGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGL 593 G G GD+GP GP GP G GP G G+ G AG G+ G G G KG+ G G PGL Sbjct: 400 PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGL 459 Query: 594 PGP------------PGPPG 601 PG PGPPG Sbjct: 460 PGEKGHRGDTGAQGLPGPPG 479 Score = 111 bits (278), Expect = 2e-24 Identities = 74/191 (38%), Positives = 85/191 (44%), Gaps = 44/191 (23%) Query: 456 RGAPGPPGPRGFKGDMGVKGP-VGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 + A GP G +G KG+ V P + GP G G G +GP G QG PG G GERGP G Sbjct: 266 QAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPG 325 Query: 515 PRGFPGLKGSKGS----------FGTGGP------------------------RGQPGPK 540 G PG G+ G FG+GG RG PGP Sbjct: 326 RAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPM 385 Query: 541 GDIGPPGPEGPPGSPGPSG------PQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP 594 G G PGP G PGSPG G PQG G G TG PG+ G +G G G G+P Sbjct: 386 GYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGR---RGRAGADGARGMP 442 Query: 595 GPPGPPGSQSF 605 G PG G + F Sbjct: 443 GDPGVKGDRGF 453 Score = 92.8 bits (229), Expect = 8e-19 Identities = 48/97 (49%), Positives = 56/97 (57%), Gaps = 9/97 (9%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPVGERG 511 L G GPPG +G KGD G+ GP G G KG+ PG+ GP+GP GP G PG AGP G +G Sbjct: 1308 LIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKG 1367 Query: 512 PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548 GP G KG G GP G PGP G++ P P Sbjct: 1368 ATGP------GGPKGEKGVQGPPGHPGPPGEVIQPLP 1398 Score = 30.0 bits (66), Expect = 6.4 Identities = 19/47 (40%), Positives = 23/47 (48%), Gaps = 16/47 (34%) Query: 573 PGQRGAMGPKG-----------EPG--IQGPPGLPGPP---GPPGSQ 603 P + A GP+G EPG ++GPPG GP GPPG Q Sbjct: 263 PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQ 309 >gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo sapiens] Length = 1736 Score = 156 bits (395), Expect = 5e-38 Identities = 79/146 (54%), Positives = 89/146 (60%), Gaps = 9/146 (6%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG PGPPGP G+ G+ G G G KGDPG G G GP G G G ERG G Sbjct: 942 RGHPGPPGP---PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG---ERGLPGT 995 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 G PGLKG++G G GP G PG +G G GP GPPG PGP GP PG AG+ G PG+ Sbjct: 996 AGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP---PGAAGEKGVPGE 1052 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPG 601 +G +GP G G+QGP GLPGP GPPG Sbjct: 1053 KGPIGPTGRDGVQGPVGLPGPAGPPG 1078 Score = 150 bits (380), Expect = 2e-36 Identities = 84/187 (44%), Positives = 96/187 (51%), Gaps = 45/187 (24%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLG------PLGPQGP------------- 497 G PGP G RG G G +G GG+G KGDPG++G P+GP GP Sbjct: 1312 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLP 1371 Query: 498 -----QGQPGEAGPVGERGPVGPRGFPGLKGSKGS---------FGTGGPRGQPGPKGDI 543 QG+PG G G GPVGP G PGL+G G+ G GP G+ G KGD Sbjct: 1372 GSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDR 1431 Query: 544 GPPGPEGPPGSP------------GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPP 591 G PGP+G PG GP GP G PG AG G+ G G GPKGE G+QGPP Sbjct: 1432 GLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPP 1491 Query: 592 GLPGPPG 598 G PGPPG Sbjct: 1492 GHPGPPG 1498 Score = 149 bits (376), Expect = 7e-36 Identities = 85/174 (48%), Positives = 99/174 (56%), Gaps = 27/174 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGPVG--GR-GPKGD---PGSLGPLGPQGPQGQPGEAGPVGER 510 G PGPPG G KG +GV G G GR GPKG PG G G +G +G G++GP GER Sbjct: 781 GDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER 840 Query: 511 GPVGPRGFPGLKGS---KGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA 567 GP GPRG G +G+ G+ GT G G GP G+ G PGP+GP G PGP GP G PG Sbjct: 841 GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKD 900 Query: 568 GKTGSPGQRGAMGPKGEPGIQGPPGL------------------PGPPGPPGSQ 603 G G PGQRG +G +G+ G GPPG+ PGPPGPPG Q Sbjct: 901 GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ 954 Score = 149 bits (375), Expect = 9e-36 Identities = 82/171 (47%), Positives = 95/171 (55%), Gaps = 24/171 (14%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGG------RGPKGDPGSLGPLGPQGPQGQPGEAGPVGER 510 G PGP GP G G+ G KG VG +G KG+ G GP GP GP GQPG AG GE Sbjct: 1069 GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEP 1128 Query: 511 GPVGPRGFPGLKGSKGSFGTGGP------RGQPGPKG------DIGPPGPEGPPGSPGPS 558 G GP+G G KG +G+ G GP +G PGP G D+GP GP GPPG GP+ Sbjct: 1129 GARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPA 1188 Query: 559 ------GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 GPQG PG G G PG++G G G PGIQG PG+ GP G G + Sbjct: 1189 GPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEK 1239 Score = 148 bits (373), Expect = 2e-35 Identities = 72/148 (48%), Positives = 84/148 (56%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L+G PGP G +G GD+G GP G GP+G G G GPQGP G G GP GE+G G Sbjct: 1157 LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1216 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574 G PG++G G G G RG+ G G G PGP GP G G GP+G PG G G PG Sbjct: 1217 ESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPG 1276 Query: 575 QRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G GP+G+ G +G G G PG PGS Sbjct: 1277 PPGEGGPRGQDGAKGDRGEDGEPGQPGS 1304 Score = 147 bits (372), Expect = 2e-35 Identities = 79/152 (51%), Positives = 89/152 (58%), Gaps = 12/152 (7%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +G PG G G +G+ GVKGP G RG KG+ G G GP GP+G G+ GP G GPVG Sbjct: 1212 KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG- 1270 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS------GPQGKPGIAGK 569 FPG G G GGPRGQ G KGD G G G PGSPGP+ GP GK G AG Sbjct: 1271 --FPGDPGPPGE---GGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1325 Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 GS G++G G KG+PG G PG GP GP G Sbjct: 1326 PGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAG 1357 Score = 145 bits (367), Expect = 8e-35 Identities = 75/153 (49%), Positives = 90/153 (58%), Gaps = 9/153 (5%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG PG +G +GD G +G G P G+ G G G GP+G PGE+GP G GP GP Sbjct: 562 GLPGLPGEKGHRGDTGAQGLPG---PPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPP 618 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS---PGPS---GPQGKPGIAGKT 570 G PG G +G G GP+G GP+G+ GPPG +G PG+ PGP GP G+ G GK Sbjct: 619 GIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKP 678 Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G PG G+ GP G PG +GPPG G GP G Q Sbjct: 679 GLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQ 711 Score = 145 bits (367), Expect = 8e-35 Identities = 76/150 (50%), Positives = 86/150 (57%), Gaps = 9/150 (6%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG---ERGPV 513 G PGPPGPRG GP G GP+G PG +G LGP G +G+PGE+G G E G Sbjct: 1177 GPPGPPGPRG------PAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVK 1230 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 GPRG G KG G G GP G GP GD GP G GP G PG GP G+ G G+ G+ Sbjct: 1231 GPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAK 1290 Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G RG G G+PG GP G GPPGP G + Sbjct: 1291 GDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1320 Score = 145 bits (366), Expect = 1e-34 Identities = 81/160 (50%), Positives = 88/160 (55%), Gaps = 12/160 (7%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP--- 512 RG G G RG GD GVKG G G G PG G G G QG PG G GERG Sbjct: 537 RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGE 596 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSG---PQGKPGIAGK 569 +GPRG PG G +G G GP G PGP G G GP+GP GS GP G P G+ G G Sbjct: 597 IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT 656 Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPG------PPGPPGSQ 603 G PG +GA+GP GE G QG PGLPG PPG PG + Sbjct: 657 QGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKE 696 Score = 145 bits (366), Expect = 1e-34 Identities = 76/152 (50%), Positives = 89/152 (58%), Gaps = 9/152 (5%) Query: 457 GAPGPPGP---RGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPV 513 GAPG GP RGF G+ G+ G GG G KG+ G P GP GP G PGE G G GP+ Sbjct: 973 GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEG---PSGPPGPAGSPGERGAAGSGGPI 1029 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQG---KPGIAGKT 570 GP G PG +G G+ G G G+ GP G G G +GP G PGP+GP G + G G+ Sbjct: 1030 GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 1089 Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G PGQ+G G KGE G GPPG GP G PG+ Sbjct: 1090 GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1121 Score = 144 bits (363), Expect = 2e-34 Identities = 76/160 (47%), Positives = 89/160 (55%), Gaps = 18/160 (11%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GA G PG RG +G G KG G RG G PG +G G GP G+ GE G VG GP GP Sbjct: 1123 GADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP- 1181 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI---------A 567 PG +G G G GP+G PG G++GPPG +G PG G G QG+PG+ Sbjct: 1182 --PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEK 1239 Query: 568 GKTGSPGQRGAMGPKGEPGIQGPPGLPGP------PGPPG 601 G++G PG+ G GPKG G GP G PGP PGPPG Sbjct: 1240 GESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG 1279 Score = 142 bits (359), Expect = 7e-34 Identities = 77/167 (46%), Positives = 91/167 (54%), Gaps = 18/167 (10%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGPVG 508 L G G PG +G +G G GP G G +G GS GP+GP QGP G GE G G Sbjct: 992 LPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPG 1051 Query: 509 ERGPVGPRGFPGLKGSKGSFGTGGP---RGQPGPKGDIGPPGPEG---------PPGSPG 556 E+GP+GP G G++G G G GP G+ G KG++G PG +G PPG PG Sbjct: 1052 EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG 1111 Query: 557 PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 P GP G+PG AG G PG RG G G G +G G GPPGP G Q Sbjct: 1112 PIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ 1158 Score = 142 bits (359), Expect = 7e-34 Identities = 74/150 (49%), Positives = 88/150 (58%), Gaps = 6/150 (4%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG PG G G+ G GP+G RGP G PGS G G +G +G PG G G+ GPVGP Sbjct: 1297 GEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPA 1356 Query: 517 G---FPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 G PG G +G G+ G +G+PG G GPPGP GPPG PG +G G G+ G P Sbjct: 1357 GPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGL---RGDAGAKGEKGHP 1413 Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G G +GP GE G +G GLPGP G PG + Sbjct: 1414 GLIGLIGPPGEQGEKGDRGLPGPQGSPGQK 1443 Score = 141 bits (356), Expect = 2e-33 Identities = 77/152 (50%), Positives = 86/152 (56%), Gaps = 9/152 (5%) Query: 460 GPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQ---GQPGEAGPVGERGPVGPR 516 GPPGP G+ G G G G G KG+ G LGP GP+GPQ G PG+AG G G G R Sbjct: 487 GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGAR 546 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ- 575 G PG G KG G G G PG KG G G +G PG PG G +G G G G PG+ Sbjct: 547 GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 606 Query: 576 --RGAMGPKGEPGIQGPP---GLPGPPGPPGS 602 RG +GPKG PGI GPP G+ GP GP GS Sbjct: 607 GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGS 638 Score = 140 bits (353), Expect = 3e-33 Identities = 81/167 (48%), Positives = 87/167 (52%), Gaps = 21/167 (12%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGP--- 506 RGA G GP G G G +GP G G KG PG GP+GP QGP G PG AGP Sbjct: 1020 RGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGV 1079 Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566 GE G G G PG KG+KG+ G GP G PGP G +G PG G G PG GPQG G Sbjct: 1080 AGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGA 1139 Query: 567 AGKTGSPGQRGAMGP------------KGEPGIQGPPGLPGPPGPPG 601 G G+ G G GP KGE G GP G PGPPGP G Sbjct: 1140 KGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG 1186 Score = 140 bits (353), Expect = 3e-33 Identities = 78/165 (47%), Positives = 86/165 (52%), Gaps = 21/165 (12%) Query: 457 GAPGPPGPRGFKGDMGVKG------------PVGGRGPKGDPGSLGPLGPQGPQGQPGEA 504 G PGPPGP+G GD G KG P G GP+G G+ G G G GQPG Sbjct: 1246 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSP 1305 Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG------PEGPPGSPGPS 558 GP GE GP GP G G GS GS G G +G G G IG PG P GP G PGP Sbjct: 1306 GPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPD 1365 Query: 559 GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G +G PG G+ G PG G GP PG GPPGLPG G G++ Sbjct: 1366 GLRGLPGSVGQQGRPGATGQAGP---PGPVGPPGLPGLRGDAGAK 1407 Score = 140 bits (352), Expect = 4e-33 Identities = 76/174 (43%), Positives = 86/174 (49%), Gaps = 27/174 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PGPPG RG G G KG +G +G G PG G G QG G G GP GE+GP G Sbjct: 619 GIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKP 678 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI---------- 566 G PG+ GS G G G G PG KG+ GP GP+GP G PGP G +G GI Sbjct: 679 GLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEK 738 Query: 567 -----------------AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G+ G PG RG GP+G G GP G PGPPG G + Sbjct: 739 GEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEK 792 Score = 140 bits (352), Expect = 4e-33 Identities = 79/173 (45%), Positives = 84/173 (48%), Gaps = 27/173 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G G GPRG G G KG GG GP G PG G GPQGP G PG GP G G G Sbjct: 844 GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLP 903 Query: 517 GFPGLKGSKGSFGTGGPRGQP------------GPKGDIGPPGPEGPP------------ 552 G PG +G G G GP G P GP G+ G PGP GPP Sbjct: 904 GHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKE 963 Query: 553 ---GSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G PGP G GK G AG G PG+RG G G PG++G G GPPGP GS Sbjct: 964 GTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGS 1016 Score = 138 bits (348), Expect = 1e-32 Identities = 78/174 (44%), Positives = 91/174 (52%), Gaps = 24/174 (13%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGG------RGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509 +G PGPPG +G G G+ GP G +GP+G PG G G GP G PG+ GP G Sbjct: 642 QGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGT 701 Query: 510 RG------PVGPRGFP---------GLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP--- 551 +G P GP G+P G++G KG G G G PG KGDIG G G Sbjct: 702 KGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV 761 Query: 552 PGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 PGS G GP+G G G TG PG G MG KG+ G+ G PG PG GP GS F Sbjct: 762 PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGF 815 Score = 137 bits (346), Expect = 2e-32 Identities = 79/166 (47%), Positives = 88/166 (53%), Gaps = 18/166 (10%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG---------EAGP 506 +G PG GP G G GV+GPVG GP G PG G G +G G PG E GP Sbjct: 1047 KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 1106 Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD------IGPPGPEGPPGSPGPSGP 560 G GP+GP G PG G+ G G GP+G G KGD GPPGP G G PGPSG Sbjct: 1107 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1166 Query: 561 QGKPGIA---GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 +G+ G G G PG RG GP G G QGPPG G GPPG + Sbjct: 1167 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEK 1212 Score = 137 bits (345), Expect = 3e-32 Identities = 76/155 (49%), Positives = 84/155 (54%), Gaps = 15/155 (9%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG G GPRG +G G +G G RG G G+ G G GP G PGE G G P GP Sbjct: 828 RGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPG---PQGP 884 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 GFPG KG G G G G PG +G++G G GPPG PG GPQ G AG+TG G+ Sbjct: 885 NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ---GAAGETGPMGE 941 Query: 576 RGAMGPKGEPGIQGPPGL---------PGPPGPPG 601 RG GP G PG QG PG PGPPG PG Sbjct: 942 RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG 976 Score = 136 bits (342), Expect = 6e-32 Identities = 74/171 (43%), Positives = 87/171 (50%), Gaps = 15/171 (8%) Query: 450 RNVTILRGAPGPPG------------PRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGP 497 R T +G PGPPG PRG G+ G +G +G +GP G PG G G GP Sbjct: 573 RGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGP 632 Query: 498 QGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD---IGPPGPEGPPGS 554 QG G GP GE GP G +G PG +G G G GP G+ GP+G G PG +GPPG Sbjct: 633 QGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 692 Query: 555 PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 PG GP G G G +G G G GP+G G+ G GL G G G F Sbjct: 693 PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF 743 Score = 135 bits (340), Expect = 1e-31 Identities = 89/223 (39%), Positives = 101/223 (45%), Gaps = 61/223 (27%) Query: 440 AVDTQHGEILRNVTI-LRGAPGP------------PGPRGFKGDMGVKGPVGGRGPK--- 483 A + Q IL+ + LRG PGP PG G KG+ G GP G RGP+ Sbjct: 469 AQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLT 528 Query: 484 ---------------------GDP------------------GSLGPLGPQGPQGQPGEA 504 GDP G G G QG G PGE Sbjct: 529 GPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED 588 Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS---GPQ 561 G G+ G +GPRG PG G +G G GP G PGP G G GP+GP GS GP GP Sbjct: 589 GERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP 648 Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP---GPPG 601 G+ G G G PG +GA+GP GE G QG PGLPG P GPPG Sbjct: 649 GQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPG 691 Score = 135 bits (340), Expect = 1e-31 Identities = 74/167 (44%), Positives = 87/167 (52%), Gaps = 21/167 (12%) Query: 456 RGAPGPPGPRGFKGDMGVKG------------------PVGGRGPKGDPGSLGPLGPQGP 497 +G G G GFKGD+GVKG P G GP GDPG G +G +G Sbjct: 735 KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 794 Query: 498 QGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEG---PPGS 554 G PG G G +GP G GFPG G+ G G G G+ GP+G+ GP GP G P G+ Sbjct: 795 LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 854 Query: 555 PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G SG +G G G G PG+RG GP+G G GP G PGPPG G Sbjct: 855 TGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDG 901 Score = 133 bits (335), Expect = 4e-31 Identities = 72/162 (44%), Positives = 82/162 (50%), Gaps = 15/162 (9%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG----- 511 G GPPGP G G+ G G G GP G PG GP G G +G PGE GP+G G Sbjct: 1006 GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 1065 Query: 512 -------PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEG---PPGSPGPSGPQ 561 P GP G G G KG G G +G G KG+ GPPGP G P G PG +G Sbjct: 1066 GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGAD 1125 Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G+PG G G G +G G +G G GP GL G PGP G + Sbjct: 1126 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEK 1167 Score = 132 bits (333), Expect = 7e-31 Identities = 76/161 (47%), Positives = 87/161 (54%), Gaps = 18/161 (11%) Query: 455 LRGAPGPPGPRGFKGDMGVKG------PVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG 508 ++G PG GPRG +G+ G G P G +GP GD GP G GP G PG+ GP G Sbjct: 1223 IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD---GPKGNPGPVGFPGDPGPPG 1279 Query: 509 ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP---EGPPGSPGPSGPQGKPG 565 E GPRG G KG +G G G G PGP G+ GPPGP GP GSPG G QG G Sbjct: 1280 EG---GPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKG 1336 Query: 566 I---AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G G+PG+ G +GP G G GP GL G PG G Q Sbjct: 1337 AKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQ 1377 Score = 129 bits (323), Expect = 1e-29 Identities = 76/157 (48%), Positives = 82/157 (52%), Gaps = 9/157 (5%) Query: 456 RGAPGPPGPRGF---KGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 RG PG GPRG KG G+ GP G RG G G G LGPQG G PG+ G G +G Sbjct: 600 RGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGL 659 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP---GSPGPSGPQGK---PGI 566 GP+G G G KG G G G PG G G PG EGPP G+ GPSGPQG PG Sbjct: 660 PGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGP 719 Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G G G RG G KGE G G PG G G G + Sbjct: 720 RGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDR 756 Score = 127 bits (318), Expect = 4e-29 Identities = 76/185 (41%), Positives = 89/185 (48%), Gaps = 39/185 (21%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPVGERGP 512 +G G PGPRG KG G++G G +G KG+ PG G +G +G +G+ G G GE GP Sbjct: 711 QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGP 770 Query: 513 VGPRGF---------PGLKGSKGSFGTGGPRGQPG---PKGDIGPP-------------- 546 GP+G PGL G KG G G G PG PKG +G P Sbjct: 771 EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 830 Query: 547 ----------GPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGP 596 GP GP G GP G GK G G +G G G G +G PG QGP G PGP Sbjct: 831 SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 890 Query: 597 PGPPG 601 GPPG Sbjct: 891 KGPPG 895 Score = 124 bits (310), Expect = 3e-28 Identities = 68/150 (45%), Positives = 76/150 (50%), Gaps = 3/150 (2%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L G PG GP G G G G G +GP G G LG GP+G +G G G G +G G Sbjct: 680 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 739 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPE---GPPGSPGPSGPQGKPGIAGKTG 571 GFPG KG G G G G PG +G+ GP GP+ GP G PGP G G+ G G G Sbjct: 740 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 799 Query: 572 SPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 PG G GPKG G G PG G G G Sbjct: 800 LPGYPGRQGPKGSLGFPGFPGASGEKGARG 829 Score = 120 bits (300), Expect = 5e-27 Identities = 69/163 (42%), Positives = 88/163 (53%), Gaps = 18/163 (11%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG-- 514 G GPPG +G +G G +GP+G GP+G G G G +G +G+ GE G G +G +G Sbjct: 694 GKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVK 753 Query: 515 -PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------PGSPGPSGPQGK- 563 RG G+ GS+G G GP+G+ GP GD GPPG G PG PG GP+G Sbjct: 754 GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL 813 Query: 564 -----PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 PG +G+ G+ G G GP+GE G GP G GP G G Sbjct: 814 GFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATG 856 Score = 112 bits (280), Expect = 1e-24 Identities = 79/207 (38%), Positives = 91/207 (43%), Gaps = 46/207 (22%) Query: 442 DTQHGEILRNVTILRGAP--GPPGPRGFKGDMGVKGP-VGGRGPKGDPGSLGPLGPQGPQ 498 +T+ G L T GA GP G +G KG+ V P + GP G G G +GP G Q Sbjct: 357 ETELGPALSAETAHSGAAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQ 416 Query: 499 GQPGEAGPVGERGPVGPRGFPGLKGSKGS----------FGTGGP--------------- 533 G PG G GERGP G G PG G+ G FG+GG Sbjct: 417 GNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQA 476 Query: 534 ---------RGQPGPKGDIGPPGPEGPPGSPGPSG------PQGKPGIAGKTGSPGQRGA 578 RG PGP G G PGP G PGSPG G PQG G G TG PG+ G Sbjct: 477 ILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGR 536 Query: 579 MGPKGEPGIQGPPGLPGPPGPPGSQSF 605 +G G G G+PG PG G + F Sbjct: 537 ---RGRAGADGARGMPGDPGVKGDRGF 560 Score = 92.8 bits (229), Expect = 8e-19 Identities = 48/97 (49%), Positives = 56/97 (57%), Gaps = 9/97 (9%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPVGERG 511 L G GPPG +G KGD G+ GP G G KG+ PG+ GP+GP GP G PG AGP G +G Sbjct: 1415 LIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKG 1474 Query: 512 PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548 GP G KG G GP G PGP G++ P P Sbjct: 1475 ATGP------GGPKGEKGVQGPPGHPGPPGEVIQPLP 1505 Score = 70.5 bits (171), Expect = 4e-12 Identities = 47/126 (37%), Positives = 53/126 (42%), Gaps = 21/126 (16%) Query: 494 PQGPQGQPGEAGPVGERGPVGPRGF---------------PGLKGSKGSFGTG--GPRGQ 536 P + Q E G G P GP + P L G GPRG Sbjct: 322 PTADRFQAEEYGEGGTDPPEGPYDYTYGYGDDYREETELGPALSAETAHSGAAAHGPRGL 381 Query: 537 PGPKGD--IGPPGP--EGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPG 592 G KG+ + PG EGPPG GP+G G PGI G G G G GP G G+ G G Sbjct: 382 KGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDG 441 Query: 593 LPGPPG 598 PGPPG Sbjct: 442 APGPPG 447 >gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] Length = 1745 Score = 156 bits (394), Expect = 6e-38 Identities = 79/163 (48%), Positives = 94/163 (57%), Gaps = 15/163 (9%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +G GPPGP G +G G++G G +G GDPG G G +GP G G G GERGP+GP Sbjct: 958 KGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGP 1017 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKT----- 570 G GL G GS G GP G+ G +G+ GPPGP G G PGP GP G PG AG + Sbjct: 1018 AGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGD 1077 Query: 571 ----------GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 GS G +G GP G+PGI+GP G PGPPG G+Q Sbjct: 1078 KGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQ 1120 Score = 152 bits (384), Expect = 9e-37 Identities = 84/186 (45%), Positives = 100/186 (53%), Gaps = 39/186 (20%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPVGERGPV 513 G PG PGPRG KG G +G G +G KG+ PG G +G +G QG+PG GP GE GP Sbjct: 704 GPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPE 763 Query: 514 GPRGFPGLKGSKGSFGTGGPR------------GQPGPKGDIGPPGPEGPPGSPGPSGPQ 561 GP+G G G +G G+ G + G+PGPKG IG PGP GP G G SG Sbjct: 764 GPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKT 823 Query: 562 GKPGIAGKTGSPGQRGAM---------GPKGE---------------PGIQGPPGLPGPP 597 G+PG+ G+ G PG RG GPKG+ PG+QGPPG PGP Sbjct: 824 GQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPK 883 Query: 598 GPPGSQ 603 GPPG Q Sbjct: 884 GPPGHQ 889 Score = 148 bits (373), Expect = 2e-35 Identities = 83/190 (43%), Positives = 98/190 (51%), Gaps = 42/190 (22%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGD------PGSLGPLGPQGPQGQPGEAGPVGE 509 RG GP GP+G G G +GP G G KG PG G GP+G G PG GP+GE Sbjct: 757 RGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGE 816 Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPG------PKGDIGP------------PGPEGP 551 +G G G PGL+G +G G+ G RGQPG PKGD+G PG +GP Sbjct: 817 KGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGP 876 Query: 552 PGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGL------------------ 593 PG PGP GP G G G+ G PGQRG +G +G+ G GP G+ Sbjct: 877 PGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGP 936 Query: 594 PGPPGPPGSQ 603 PGPPGPPG Q Sbjct: 937 PGPPGPPGEQ 946 Score = 147 bits (372), Expect = 2e-35 Identities = 80/162 (49%), Positives = 94/162 (58%), Gaps = 15/162 (9%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQG---PQGQPGEAGPVGERGPV 513 G PGP GP G +G G G G RG G G GP GP G PQG+ GE GP+GERGP Sbjct: 878 GFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPP 937 Query: 514 GP------RGFPGL---KGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS---GPQ 561 GP +G PGL +G+KG G GP G+ GP G G PGP+G PG PGP+ G + Sbjct: 938 GPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDK 997 Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G PG G GSPG+RG +GP G G+ G G GP GP G + Sbjct: 998 GPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKK 1039 Score = 147 bits (371), Expect = 3e-35 Identities = 75/154 (48%), Positives = 88/154 (57%), Gaps = 9/154 (5%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G G PGP G G+ G GP G RGP G G G G +G +G+PG GP G GP+G R Sbjct: 1289 GDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGAR 1348 Query: 517 GFPGLKGSKGSFGTGGPRGQPG---PKGDIGPPGPEGPPGSPG------PSGPQGKPGIA 567 G PG G +G G GP G+PG G +GPPGP GP G PG P G +G G+ Sbjct: 1349 GPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLI 1408 Query: 568 GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G PG+ G G +G PG+QGPPG G PGPPG Sbjct: 1409 GLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPG 1442 Score = 147 bits (370), Expect = 4e-35 Identities = 79/151 (52%), Positives = 88/151 (58%), Gaps = 6/151 (3%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP---LGPQGPQGQPGEAGPVGERGPV 513 GAPGPPG RG G MG +G G +G KG+PG GP GP G +G PG GP G RG Sbjct: 1304 GAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIP 1363 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQ---PGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKT 570 GP G PGL G+ G G GP G PG KGD GP G +G G G GP G+ G G Sbjct: 1364 GPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQ 1423 Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G PG +G GPKG+PG GP G G PGPPG Sbjct: 1424 GLPGVQGPPGPKGDPGPPGPIGSLGHPGPPG 1454 Score = 146 bits (369), Expect = 5e-35 Identities = 78/164 (47%), Positives = 89/164 (54%), Gaps = 15/164 (9%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGG---RGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG 511 L+G PGPPG +G GD+G GP G RGP+G GS G G G GQPG G GERG Sbjct: 1149 LQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERG 1208 Query: 512 PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS------------PGPSG 559 G G PG G G G G +G GP G GPPG +GPPG PG G Sbjct: 1209 DAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLG 1268 Query: 560 PQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 P G PG++G GSPG++G G G PG G G PG PGPPG + Sbjct: 1269 PPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKR 1312 Score = 143 bits (361), Expect = 4e-34 Identities = 75/159 (47%), Positives = 91/159 (57%), Gaps = 9/159 (5%) Query: 456 RGAPGP------PGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509 +G PGP PG +G G+ G+ G G GP G PG GP G +G QG PG AGP G Sbjct: 649 QGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGY 708 Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP---SGPQGKPGI 566 GP G +G G +G +G G G G PG KGD+G G +G PG+PGP GP+G G Sbjct: 709 PGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQ 768 Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 AG+ G G G+ G KG+ G+ G PG PG PGP GS F Sbjct: 769 AGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGF 807 Score = 143 bits (360), Expect = 5e-34 Identities = 77/162 (47%), Positives = 89/162 (54%), Gaps = 18/162 (11%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +G PGP GP G G MG +GP G GP+G G GP+G G G PG+ GP GP+GP Sbjct: 1330 KGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGP---PGPLGP 1386 Query: 516 RGFPGLKGSKGS---------FGTGGPRGQPGPKGD------IGPPGPEGPPGSPGPSGP 560 G PGLKG G G GP G+ G KGD GPPGP+G PG PGP G Sbjct: 1387 SGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGS 1446 Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G PG G G GQ+G+ G G G +G G GPPGPPG+ Sbjct: 1447 LGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGA 1488 Score = 142 bits (357), Expect = 1e-33 Identities = 78/150 (52%), Positives = 88/150 (58%), Gaps = 12/150 (8%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG---EAGPVGERGPV 513 GA GPPG G +G G+ GPVG G G PG +GP GP GP G PG + GP GE+G + Sbjct: 1346 GARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHI 1405 Query: 514 GPRGF---PGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKT 570 G G PG G KG G G +G PGPKGD GPPGP G G PGP G G G G Sbjct: 1406 GLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSK 1465 Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPP 600 GSPG +MGP+G+ G GPPG PPG P Sbjct: 1466 GSPG---SMGPRGDTGPAGPPG---PPGAP 1489 Score = 141 bits (356), Expect = 2e-33 Identities = 75/145 (51%), Positives = 84/145 (57%), Gaps = 9/145 (6%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G+ GP GP G KG G +GP G G G PG LGPLGP PG AGP GE G G Sbjct: 1028 GSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGP------PGAAGPSGEEGDKGDV 1081 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G PG KGSKG G GP GQPG +G G PGP PG+ G G +G PG+ G+ G G R Sbjct: 1082 GAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGP---PGADGAQGRRGPPGLFGQKGDDGVR 1138 Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPG 601 G +G G PG+QG PG PG G G Sbjct: 1139 GFVGVIGPPGLQGLPGPPGEKGEVG 1163 Score = 141 bits (356), Expect = 2e-33 Identities = 78/157 (49%), Positives = 85/157 (54%), Gaps = 12/157 (7%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRG---PKGDPGSLGPLGPQGPQGQPGEAGPVGE---R 510 G PG G +G +GD G GP G G PKGD G G GP G G PG+ GP GE + Sbjct: 1196 GQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAK 1255 Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD---IGPPGPEGPPGSPGPSGPQGKPGIA 567 G VGP G PG G G G G G PG KGD +G PGP G G PG GP GK G + Sbjct: 1256 GSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPS 1315 Query: 568 GKTGSPGQRGAMGPKGEPGIQGPPGLPGP---PGPPG 601 G G G+ G G KGEPG GPPG GP GPPG Sbjct: 1316 GHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPG 1352 Score = 140 bits (354), Expect = 3e-33 Identities = 76/157 (48%), Positives = 88/157 (56%), Gaps = 12/157 (7%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG PG +G +GD G G G G G+ G+ GP GP G G+PG G +G RG GP Sbjct: 554 GLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPT 613 Query: 517 GFPG---LKGSKGSFGTGGPRGQPGPKGDIGP------PGPEGPPGSPGPSGPQGKPGIA 567 G PG + G+ G+ G GP G+PGP G G PGP+G G+PG GP G PGI Sbjct: 614 GRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIP 673 Query: 568 GKTGSP---GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G GS G G GP GE G QGPPG GPPG PG Sbjct: 674 GLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPG 710 Score = 140 bits (352), Expect = 4e-33 Identities = 78/170 (45%), Positives = 93/170 (54%), Gaps = 21/170 (12%) Query: 455 LRGAPGP---PGPRGFKGDMGVKGPVGGRG---PKGDPGSLGPLG---PQGPQGQPGEAG 505 L G PGP PG G KG+ G +GP G RG P G PG +G +G G +G PG+ G Sbjct: 486 LTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTG 545 Query: 506 PVGERGPVGPRGFPGLKGSKGSFG---TGGPRGQPGPKGDIGPPGPEGPPGSPGPSG--- 559 P G+RG G G PG KG +G FG GP G+ G +G GPPGP G G PGP G Sbjct: 546 PKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLG 605 Query: 560 ------PQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 P G+PG+ G G+PG +G +GP GEPG G G G G PG Q Sbjct: 606 PRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQ 655 Score = 139 bits (350), Expect = 8e-33 Identities = 78/169 (46%), Positives = 85/169 (50%), Gaps = 24/169 (14%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGP---KGDPGSLGPLGPQGPQGQPGEAGPVGERGPV 513 GAPG PGP+G G+ G GP G GP KG PG G G GP G PG+ GP G+ G Sbjct: 1217 GAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVS 1276 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPG---------------SPGPS 558 G G PG KG G G GP G G G GPPG GP G PGP Sbjct: 1277 GIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPD 1336 Query: 559 GPQGKPGIAGKTGSPGQ------RGAMGPKGEPGIQGPPGLPGPPGPPG 601 GP G+ G G G PG+ RG GP GEPG+ G PG GPPGP G Sbjct: 1337 GPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLG 1385 Score = 139 bits (349), Expect = 1e-32 Identities = 74/167 (44%), Positives = 86/167 (51%), Gaps = 18/167 (10%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 ++G PGP G G G +G+ G G +G +G G GP G QGP G PG G +G G G Sbjct: 477 MKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADG 536 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKG---DIGPPGPEGPPGSPGPSGPQGKPGIAGKTG 571 RG PG G KG G G G PG KG D G G GPPG G G +G PG G+ G Sbjct: 537 ARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAG 596 Query: 572 SPGQRGAMGPKGEPGIQGPPGL---------------PGPPGPPGSQ 603 PG RG +GP+G PG G PG+ PG PGPPG Q Sbjct: 597 EPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQ 643 Score = 139 bits (349), Expect = 1e-32 Identities = 81/178 (45%), Positives = 91/178 (51%), Gaps = 33/178 (18%) Query: 457 GAPGPPGPRG---FKGDMGVKGPVGGRGPKGDPGSLGPLG---PQGPQGQPGE------- 503 G PG PG RG F+G G GP G GP+G G +GPLG P GP G PGE Sbjct: 893 GRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLE 952 Query: 504 -----------AGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDI--------- 543 GP+G+ GP G RGFPG KG G G G +G GP G + Sbjct: 953 GREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGER 1012 Query: 544 GPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 GP GP G G PG SG +G G AGK GS G+RG GP G+ GI GP G GPPG G Sbjct: 1013 GPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAG 1070 Score = 138 bits (347), Expect = 2e-32 Identities = 72/148 (48%), Positives = 83/148 (56%), Gaps = 6/148 (4%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GAPG G +G KGD G G G RGP G PG P G G QG+ G G G++G G R Sbjct: 1082 GAPGHKGSKGDKGDAGPPGQPGIRGPAGHPG---PPGADGAQGRRGPPGLFGQKGDDGVR 1138 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGP---QGKPGIAGKTGSP 573 GF G+ G G G GP G+ G GD+G GP G PG GP GP +G PG+ G G P Sbjct: 1139 GFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQP 1198 Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G G +G+ G GPPG PG PGP G Sbjct: 1199 GAVGEKGERGDAGDPGPPGAPGIPGPKG 1226 Score = 137 bits (345), Expect = 3e-32 Identities = 75/157 (47%), Positives = 84/157 (53%), Gaps = 12/157 (7%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGD------PGSLGPLGPQGP------QGQPGEA 504 GA GP G G KGD+G G G +G KGD PG GP G GP QG+ G Sbjct: 1067 GAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPP 1126 Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564 G G++G G RGF G+ G G G GP G+ G GD+G GP G PG GP GP G Sbjct: 1127 GLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSE 1186 Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G G GQ GA+G KGE G G PG PG PG PG Sbjct: 1187 GTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPG 1223 Score = 135 bits (341), Expect = 8e-32 Identities = 70/146 (47%), Positives = 80/146 (54%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG PG G G KGD+G G G G KG PG GP G GP+G PG G G G G Sbjct: 841 RGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQ 900 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 RG G +G G G G G G G++GP G GPPG PGP G QG PG+ G+ G+ G+ Sbjct: 901 RGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGE 960 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPG 601 G GP G+ G G G PGP G PG Sbjct: 961 LGPPGPLGKEGPAGLRGFPGPKGGPG 986 Score = 135 bits (341), Expect = 8e-32 Identities = 76/168 (45%), Positives = 90/168 (53%), Gaps = 21/168 (12%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGS------LGPLGPQGPQGQPGEAGPVG 508 +RG G PGP G G G +GP G G KGD G +GP G QG G PGE G VG Sbjct: 1104 IRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVG 1163 Query: 509 ERGPVGPRGFPGLKGSKGSFGTGGPRGQP------------GPKGDIGPPGPEGPPGSPG 556 + G +GP G PG +G +G G+ G G P G +GD G PGP G PG PG Sbjct: 1164 DVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPG 1223 Query: 557 PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQ---GPPGLPGPPGPPG 601 P G G+ G +G +G+ G G GP GE G + GP GLPG GPPG Sbjct: 1224 PKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPG 1271 Score = 135 bits (339), Expect = 1e-31 Identities = 72/152 (47%), Positives = 82/152 (53%), Gaps = 6/152 (3%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV---GERGP 512 RG+PGP G G G G G G GP G+PG G G G QG PG G + GE+GP Sbjct: 607 RGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGP 666 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP---SGPQGKPGIAGK 569 G G PGL GS G G G G G KG GPPG GPPG PGP G G G+ G+ Sbjct: 667 PGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGE 726 Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G+ G G KG+ G++G G PG PGP G Sbjct: 727 KGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRG 758 Score = 134 bits (337), Expect = 2e-31 Identities = 72/154 (46%), Positives = 81/154 (52%), Gaps = 9/154 (5%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG PG G KGD+G KG G G G PG GP G G +G G G G+ GP G Sbjct: 1214 GPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDP 1273 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS---- 572 G G+ GS G G G G PGP G G PG GPPG GPSG G+ G G+ G+ Sbjct: 1274 GVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEP 1333 Query: 573 -----PGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 PG+ G MG +G PG GP GL G PGP G Sbjct: 1334 GPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVG 1367 Score = 133 bits (334), Expect = 5e-31 Identities = 68/145 (46%), Positives = 79/145 (54%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PGP G G G G+ G G G +G PG GP GP G QG+ G G G+RG +G + Sbjct: 848 GQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQ 907 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G G G G G G G+ GP G+ GPPGP GPPG G G +G+ G G+ G PG Sbjct: 908 GQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPL 967 Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPG 601 G GP G G GP G PG PGP G Sbjct: 968 GKEGPAGLRGFPGPKGGPGDPGPTG 992 Score = 130 bits (328), Expect = 3e-30 Identities = 72/148 (48%), Positives = 78/148 (52%), Gaps = 3/148 (2%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GA G PG G KGD G G G G KG G G +G GP G+ GE G G GP G Sbjct: 536 GARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQA 595 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEG---PPGSPGPSGPQGKPGIAGKTGSP 573 G PG +G G G+ GP G+PG G G PG +G PPG PGP G QG G G G Sbjct: 596 GEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQ 655 Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G G KG PG G PGLPG GP G Sbjct: 656 GLIGTPGEKGPPGNPGIPGLPGSDGPLG 683 Score = 130 bits (327), Expect = 3e-30 Identities = 75/165 (45%), Positives = 84/165 (50%), Gaps = 18/165 (10%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG GP GP G G MG G G RG GD G G G G G PGE G G+ G VG Sbjct: 514 RGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQ 573 Query: 516 RGFPGLKGSKGSFGTGGPRGQ---PGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572 G PG G +G+ G GP GQ PGP+G +GP G GP G PG +G G PG G G Sbjct: 574 PGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGP 633 Query: 573 PGQRGAMGPKGE---------------PGIQGPPGLPGPPGPPGS 602 PG+ G G +G PG +GPPG PG PG PGS Sbjct: 634 PGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGS 678 Score = 126 bits (316), Expect = 7e-29 Identities = 73/151 (48%), Positives = 79/151 (52%), Gaps = 15/151 (9%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GAPG PG +G G ++GP G GPKG PG G G G GQ GE G G+ GP GP Sbjct: 860 GAPGIPGEKGLPG---LQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPA 916 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQ------GKPGIAGKT 570 G G +G G G G RG P GPPGP G G PG G + G PG GK Sbjct: 917 GVLGPQGKTGEVGPLGERGPP------GPPGPPGEQGLPGLEGREGAKGELGPPGPLGKE 970 Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G RG GPKG PG GP GL G GPPG Sbjct: 971 GPAGLRGFPGPKGGPGDPGPTGLKGDKGPPG 1001 Score = 117 bits (294), Expect = 2e-26 Identities = 71/149 (47%), Positives = 79/149 (53%), Gaps = 24/149 (16%) Query: 455 LRGAPGP---PGPRGFKGDMGVKGPVGGR---GPKGDPGSLGPLGPQGPQGQPGEAGPVG 508 LRG PGP PG G G MG GP+G G KGD GP+G+ G G +G Sbjct: 1359 LRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGD---------TGPKGEKGHIGLIG 1409 Query: 509 ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAG 568 GP PG G KG G G +G PGPKGD GPPGP G G PGP G G G G Sbjct: 1410 LIGP------PGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKG 1463 Query: 569 KTGSPGQRGAMGPKGEPGIQGPPGLPGPP 597 GSP G+MGP+G+ G GPPG PG P Sbjct: 1464 SKGSP---GSMGPRGDTGPAGPPGPPGAP 1489 Score = 114 bits (285), Expect = 3e-25 Identities = 75/194 (38%), Positives = 86/194 (44%), Gaps = 48/194 (24%) Query: 456 RGAPGP---PGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP-------------QGP-- 497 +G GP PGP GF GD G GP G G G G GP G +GP Sbjct: 400 QGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPV 459 Query: 498 ------------------QGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGP 539 +G PG G G GPVG G PGLKG +G+ G GPRG GP Sbjct: 460 SFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGP 519 Query: 540 K------GDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPP-- 591 G +G PG +G G PG +GP+G G G G PG++G G G G GPP Sbjct: 520 HGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGE 579 Query: 592 ----GLPGPPGPPG 601 G GPPGP G Sbjct: 580 DGERGAEGPPGPTG 593 Score = 110 bits (274), Expect = 5e-24 Identities = 62/141 (43%), Positives = 75/141 (53%), Gaps = 6/141 (4%) Query: 455 LRGAPG---PPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG 511 L GAPG PPGP G G G+KG G +G KG G +G +GP G G+ G+ G G +G Sbjct: 1371 LLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQG 1430 Query: 512 PVGPRGFPGLKGSKGSFGTGGPRGQPGP---KGDIGPPGPEGPPGSPGPSGPQGKPGIAG 568 P GP+G PG G GS G GP G GP KG G PG GP G GP+GP G PG Sbjct: 1431 PPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAPA 1490 Query: 569 KTGSPGQRGAMGPKGEPGIQG 589 + +R P P ++G Sbjct: 1491 ELHGLRRRRRFVPVPLPVVEG 1511 Score = 104 bits (260), Expect = 2e-22 Identities = 72/173 (41%), Positives = 77/173 (44%), Gaps = 36/173 (20%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG-- 514 G PG PGP+G VG GP G PG G GP GP G PG G G RGP G Sbjct: 392 GPPGAPGPQGV---------VGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTV 442 Query: 515 ---PRGFPG--LKGSKGSFGTG-----------GPRGQPGPKGDIGPPGPEGPPGSPG-- 556 P F G KG SF +G PGP G G PGP G PG PG Sbjct: 443 IMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLK 502 Query: 557 ----PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 GPQG G+ G G PG+ G MG PG G GLPG GP G + F Sbjct: 503 GEEGAEGPQGPRGLQGPHGPPGRVGKMG---RPGADGARGLPGDTGPKGDRGF 552 Score = 68.2 bits (165), Expect = 2e-11 Identities = 52/161 (32%), Positives = 64/161 (39%), Gaps = 40/161 (24%) Query: 483 KGDPGSLGP--LGPQGPQGQPGEAGP-VGERGPVG-PRGFPGLKGSKGSFGTGGPRGQPG 538 +GD ++GP + P + P GE+G G P + +G G GP+G G Sbjct: 345 EGDDSTMGPDFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVG 404 Query: 539 PKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG------------------------ 574 P G GPPG G PG PGP+G G PGI G G PG Sbjct: 405 PSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQA 464 Query: 575 ------------QRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 +G GP G G GP GLPG PG G + Sbjct: 465 QAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEE 505 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 155 bits (392), Expect = 1e-37 Identities = 78/156 (50%), Positives = 90/156 (57%), Gaps = 12/156 (7%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L+G PGPPG +G GD+G GP G GP+G G G GPQGP G G G VGE+G G Sbjct: 1211 LQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG 1270 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS---PGPSGPQGKPGIAGKTG 571 G PG G G GGP+G+ G KG+ GPPG GPPG+ PG GP+G PG G G Sbjct: 1271 EAGNPG---PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPG 1327 Query: 572 SPGQRGAMGPKGEPGI------QGPPGLPGPPGPPG 601 PG G GP G+ G+ G PG PGPPGP G Sbjct: 1328 DPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSG 1363 Score = 152 bits (383), Expect = 1e-36 Identities = 78/147 (53%), Positives = 88/147 (59%), Gaps = 9/147 (6%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG PGPPGP G+ G+ G G G KGDP GP G G G G G GERG G Sbjct: 996 RGHPGPPGP---PGEQGLPGAAGKEGAKGDP---GPQGISGKDGPAGLRGFPGERGLPGA 1049 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 +G PGLKG +G G GP G PG +G G GP G PG PGP GP PG AG+ G+PG+ Sbjct: 1050 QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGP---PGPAGEKGAPGE 1106 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPGS 602 +G GP G G+QGP GLPGP GP GS Sbjct: 1107 KGPQGPAGRDGVQGPVGLPGPAGPAGS 1133 Score = 152 bits (383), Expect = 1e-36 Identities = 78/156 (50%), Positives = 88/156 (56%), Gaps = 12/156 (7%) Query: 457 GAPGPPGPRGFKGDMGVKGP---------VGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV 507 G PGPPGPRG +G G GP VGG G KG+PG G GP G G G G Sbjct: 1231 GPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGER 1290 Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA 567 GE+G GP G G G+KG G GP+G PGP +G PG GPPG PGP+G G G Sbjct: 1291 GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGP---VGFPGDPGPPGEPGPAGQDGVGGDK 1347 Query: 568 GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G+ G PGQ G GP GE G GPPG GPPG G++ Sbjct: 1348 GEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1383 Score = 150 bits (380), Expect = 2e-36 Identities = 78/148 (52%), Positives = 89/148 (60%), Gaps = 9/148 (6%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG G PG G KG G +GP G GP GD G G G GP+G PGEAGP RG +GP Sbjct: 612 RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGP---RGLLGP 668 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 RG PG G G G GP PGPKG++GP G GPPG G GPQG PG G G PG+ Sbjct: 669 RGTPGAPGQPGMAGVDGP---PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGE 725 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 + GP+G+PG+ G PG GPPG PG + Sbjct: 726 K---GPQGKPGLAGLPGADGPPGHPGKE 750 Score = 150 bits (380), Expect = 2e-36 Identities = 81/167 (48%), Positives = 93/167 (55%), Gaps = 18/167 (10%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLG------PQGPQGQPGEAGPVG 508 L GA G PG +G +G G GPVG G +G G+ GP+G PQGP G GE G G Sbjct: 1046 LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1105 Query: 509 ERGPVGPRGFPGLKGSKGSFGTGGPRGQP---GPKGDIGPPGPE---------GPPGSPG 556 E+GP GP G G++G G G GP G P G KG+IG PG + GPPG PG Sbjct: 1106 EKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG 1165 Query: 557 PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 GP G PGIAG G PG RG G G+ G +G G PGPPGP G Q Sbjct: 1166 LQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ 1212 Score = 150 bits (379), Expect = 3e-36 Identities = 78/160 (48%), Positives = 94/160 (58%), Gaps = 12/160 (7%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVG--GR-------GPKGDPGSLGPLGPQGPQGQPGEAGP 506 +G PGP G G +G G GP+G GR GP G+ G+ G GPQGP G+ G GP Sbjct: 1062 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1121 Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP---EGPPGSPGPSGPQGK 563 VG GP GP G PG G KG G G +G G KG+ GPPGP +GP G+PG +G G+ Sbjct: 1122 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGE 1181 Query: 564 PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 PG G+ G GQ+G G +G PG GP GL G PGPPG + Sbjct: 1182 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1221 Score = 149 bits (376), Expect = 7e-36 Identities = 75/145 (51%), Positives = 85/145 (58%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G GPPG G +G G KG G G +G PG GP+GPQGP G+PG G G GPVG + Sbjct: 1372 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1431 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G PG G G G GP G PG KGD G G +G PG G GP G+ G G G PG + Sbjct: 1432 GLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1491 Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPG 601 G+ G KG+ GI GP G GPPGPPG Sbjct: 1492 GSPGAKGDGGIPGPAGPLGPPGPPG 1516 Score = 147 bits (371), Expect = 3e-35 Identities = 79/168 (47%), Positives = 93/168 (55%), Gaps = 4/168 (2%) Query: 438 MKAVDTQHGEILRNVTI-LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQG 496 + A + Q IL+ I LRG PGP G G G +G G G +G GDPG GP G QG Sbjct: 521 ISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQG 580 Query: 497 PQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPG 556 P G G+ G G G G RG PG G+KG G G G PG KG G GP+GPPG PG Sbjct: 581 PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 640 Query: 557 PSGPQGKPGIAGKTGSPGQ---RGAMGPKGEPGIQGPPGLPGPPGPPG 601 G +G+ G G G PG+ RG +GP+G PG G PG+ G GPPG Sbjct: 641 DDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 688 Score = 146 bits (369), Expect = 5e-35 Identities = 73/146 (50%), Positives = 82/146 (56%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +G PG G G G+ GV GP G RG KG+ G G GP G +G PG+ GP G GPVG Sbjct: 1266 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1325 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 G PG G G G G G G GD G PGP GP G GP GP GK G G G+ G+ Sbjct: 1326 PGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGR 1385 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPG 601 +G G KGE G +GPPG GP GP G Sbjct: 1386 QGEKGAKGEAGAEGPPGKTGPVGPQG 1411 Score = 145 bits (366), Expect = 1e-34 Identities = 76/170 (44%), Positives = 90/170 (52%), Gaps = 24/170 (14%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG---ERGP 512 RG PG PG G G G GP G GP+G+PG G G GPQG PG GP+G E+GP Sbjct: 669 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 728 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572 G G GL G+ G G G GQ G KG +GPPGP+GP G PGP G +G G+ G GS Sbjct: 729 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 788 Query: 573 PGQR---------------------GAMGPKGEPGIQGPPGLPGPPGPPG 601 G++ G +GP+GE G +GP G GP G PG Sbjct: 789 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 838 Score = 144 bits (364), Expect = 2e-34 Identities = 84/174 (48%), Positives = 94/174 (54%), Gaps = 27/174 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGPVG--GR-GPKGD---PGSLGPLGPQGPQGQPGEAGPVGER 510 G PGP G G KG +GV G G GR GPKG PG G G +G +G G+ GP G+R Sbjct: 835 GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 894 Query: 511 GPVGPRGFPGLKGSKGS---FGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP--- 564 GP GPRG G +G G GT G G PGP G+ GP GP+GP G PGP GP G P Sbjct: 895 GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 954 Query: 565 ------------GIAGKTGSPGQRGAMGPKGEPGIQGP---PGLPGPPGPPGSQ 603 G GKTG PG G +GP+G G GP G PGPPGPPG Q Sbjct: 955 GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQ 1008 Score = 144 bits (364), Expect = 2e-34 Identities = 82/189 (43%), Positives = 93/189 (49%), Gaps = 42/189 (22%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG- 514 RG G PGPRG +G G +G G RGP G PG G G GP G PGE GP G +GPVG Sbjct: 882 RGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGF 941 Query: 515 --PRG---------FPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------PGS 554 P+G PG G +G G G G PGP G +GP GP G PG Sbjct: 942 PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 1001 Query: 555 PGPSGPQGKPGIAGKTGS---------------------PGQRGAMGPKGEPGIQGPPGL 593 PGP G QG PG AGK G+ PG+RG G +G PG++G G Sbjct: 1002 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1061 Query: 594 PGPPGPPGS 602 GPPGP GS Sbjct: 1062 QGPPGPVGS 1070 Score = 144 bits (364), Expect = 2e-34 Identities = 74/150 (49%), Positives = 86/150 (57%), Gaps = 6/150 (4%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 + G GP G RGF G+ G+ G G G KG G P GP GP G PGE G G GP+G Sbjct: 1028 ISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEG---PQGPPGPVGSPGERGSAGTAGPIG 1084 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP---GIAGKTG 571 G PG +G G G G G+ GP+G G G +GP G PGP+GP G P G G+ G Sbjct: 1085 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG 1144 Query: 572 SPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 PGQ+G+ G KGE G GPPGL GP G PG Sbjct: 1145 EPGQKGSKGDKGENGPPGPPGLQGPVGAPG 1174 Score = 144 bits (363), Expect = 2e-34 Identities = 78/159 (49%), Positives = 87/159 (54%), Gaps = 12/159 (7%) Query: 457 GAPGPPG------PRGFKGDMGVKGPVGGRGP---KGDPGSLGPLGPQGPQGQPGEAGPV 507 G PGPPG P+G +G+ G GP G GP KG PG GP G GP G PG+ GP Sbjct: 1273 GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP 1332 Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI- 566 GE GP G G G KG G G GP G G G GPPG GPPG+ G G QG+ G Sbjct: 1333 GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAK 1392 Query: 567 --AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 AG G PG+ G +GP+G G GP GL G PGP G Q Sbjct: 1393 GEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1431 Score = 143 bits (360), Expect = 5e-34 Identities = 75/164 (45%), Positives = 88/164 (53%), Gaps = 18/164 (10%) Query: 456 RGAPGPPGPRGFKGDMGVKGP---VGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG- 511 +G G G GFKGDMG+KG VG GP+G+ G GP G GP G PG +G GE+G Sbjct: 789 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 848 Query: 512 --------------PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP 557 P G GFPG G+ G G G G+PGP+G GP GP G G+ GP Sbjct: 849 LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 908 Query: 558 SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 +G G G +G G PG G GP+G G G PG GPPGPPG Sbjct: 909 TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPG 952 Score = 142 bits (359), Expect = 7e-34 Identities = 77/156 (49%), Positives = 92/156 (58%), Gaps = 12/156 (7%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP---LGPQGPQGQPGEAGPVGERGP 512 RG GP GP G GD G++G G GP+G PG GP LGP+G G PG+ G G GP Sbjct: 627 RGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP 686 Query: 513 VGPRGFPGLKGSKG---SFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS---GPQGKPGI 566 GP+G G +G G G GP+G PGP+G IGPPG +GP G PG + G G PG Sbjct: 687 PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 746 Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 GK G G++GA+GP PG QGP G PGP G G+ Sbjct: 747 PGKEGQSGEKGALGP---PGPQGPIGYPGPRGVKGA 779 Score = 142 bits (359), Expect = 7e-34 Identities = 83/186 (44%), Positives = 94/186 (50%), Gaps = 39/186 (20%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGG---RGPKGDPGSLGPLGP---QGPQGQPGEAGPVGER 510 G PGP GP G G+ G KG +G +G KGD G GP GP QGP G PG AG GE Sbjct: 1123 GLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEP 1182 Query: 511 GP------------VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS 558 GP G RGFPG G G G GP G+ G GD+GP GP GPPG GP Sbjct: 1183 GPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ 1242 Query: 559 GP---------------------QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP 597 GP +G+PG AG G PG+ G GPKGE G +G G PG Sbjct: 1243 GPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAA 1302 Query: 598 GPPGSQ 603 GPPG++ Sbjct: 1303 GPPGAK 1308 Score = 141 bits (356), Expect = 2e-33 Identities = 77/156 (49%), Positives = 91/156 (58%), Gaps = 9/156 (5%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +GAPG GP+G G GV+GPVG GP G GS G G +G G+PG+ G G++G GP Sbjct: 1101 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP 1160 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP------PGSPGPSGPQGKPGIAGK 569 G PGL+G G+ G G G+PGP+G G G +G PG PGP G QG PG G+ Sbjct: 1161 PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1220 Query: 570 TGSPGQRGAMGPKGEP---GIQGPPGLPGPPGPPGS 602 G G G MGP G P G QGP G GP GPPGS Sbjct: 1221 KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGS 1256 Score = 141 bits (356), Expect = 2e-33 Identities = 77/165 (46%), Positives = 84/165 (50%), Gaps = 18/165 (10%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQ------------PGEA 504 G PG GP G KG G GP G GP G PG GP G GP GQ PG+ Sbjct: 1297 GPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP 1356 Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564 GP G G GP G PG +G G+ G G +G+ G KG+ G GP G G GP GP GKP Sbjct: 1357 GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1416 Query: 565 ------GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 GI G G G GA G G PG GPPGLPG G PGS+ Sbjct: 1417 GPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSK 1461 Score = 141 bits (355), Expect = 2e-33 Identities = 72/154 (46%), Positives = 87/154 (56%), Gaps = 6/154 (3%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 + G G PGPRG +G G KG G RG G PG P+G QG G PGE G G+ GP+G Sbjct: 1175 IAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG---PIGLQGLPGPPGEKGENGDVGPMG 1231 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574 P G PG +G +G G GP+G PG G +G G +G PG G GP G+ G+ G G G Sbjct: 1232 PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERG 1291 Query: 575 QRGAMGPKGE---PGIQGPPGLPGPPGPPGSQSF 605 ++G GP G PG +GPPG GP G PG F Sbjct: 1292 EKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1325 Score = 140 bits (354), Expect = 3e-33 Identities = 72/156 (46%), Positives = 85/156 (54%), Gaps = 6/156 (3%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G G PG RG G G G GG GP+G PG +G G +G G G G G GP GP Sbjct: 1036 GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPP 1095 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G G KG+ G G GP G+ G +G +G PGP GP GSPG G +G+ G G+ GS G + Sbjct: 1096 GPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDK 1155 Query: 577 GAMGPKGEPGIQGPPGLP------GPPGPPGSQSFY 606 G GP G PG+QGP G P G PGP G Q + Sbjct: 1156 GENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMF 1191 Score = 140 bits (353), Expect = 3e-33 Identities = 75/148 (50%), Positives = 81/148 (54%), Gaps = 6/148 (4%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG PGP G G G G G +G GDPG GP GP G G PG G G G G Sbjct: 1324 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1383 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGP---PGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 G G KG+KG G GP G+ GP G GP PGPEG G PGP G QG PG AG+ G P Sbjct: 1384 GRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1443 Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G MGP G PG++G PG G G PG Sbjct: 1444 ---GPMGPPGLPGLKGDPGSKGEKGHPG 1468 Score = 139 bits (349), Expect = 1e-32 Identities = 77/171 (45%), Positives = 95/171 (55%), Gaps = 24/171 (14%) Query: 457 GAPGP------PGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPV 507 G PGP PGPRG KG GV+G G +G KG+ PG G +G +G +G+ G+ GP Sbjct: 760 GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 819 Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP------PGSPGPSGPQ 561 GE GP GP+G G G G G G +G+ G G G PG +GP PG PG +G + Sbjct: 820 GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 879 Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP---------GPPGPPGSQ 603 G G+AGK G GQRG GP+G G +GP G P GPPGPPG + Sbjct: 880 GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 930 Score = 137 bits (346), Expect = 2e-32 Identities = 81/169 (47%), Positives = 85/169 (50%), Gaps = 21/169 (12%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGPVG- 508 RG+ G GP G G G +GP G G KG PG GP GP QGP G PG AGP G Sbjct: 1074 RGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1133 Query: 509 --ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGK--- 563 E G G G PG KGSKG G GP G PG +G +G PG G G PGP G QG Sbjct: 1134 PGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQ 1193 Query: 564 ---------PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 PG G G G G G KGE G GP G PGPPGP G Q Sbjct: 1194 KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ 1242 Score = 137 bits (344), Expect = 4e-32 Identities = 75/164 (45%), Positives = 88/164 (53%), Gaps = 21/164 (12%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +G G GP G G +G +GP G GP+G G GP+ G QG PG AG G GP+GP Sbjct: 1392 KGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV---GEQGLPGAAGQDGPPGPMGP 1448 Query: 516 RGFPGLKGSKGS---------FGTGGPRGQPGPKGDIGPPGPEGPPGS---------PGP 557 G PGLKG GS G GP G+ G KGD G PG +G PG+ GP Sbjct: 1449 PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGP 1508 Query: 558 SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 GP G PG+ G G G +G+ GP G+ G G PG PG PGPPG Sbjct: 1509 LGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1552 Score = 136 bits (343), Expect = 5e-32 Identities = 78/174 (44%), Positives = 91/174 (52%), Gaps = 24/174 (13%) Query: 456 RGAPGPPG------PRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509 +G PGPPG P+G G G GP G +GP+G PG G G GP G PG+ G GE Sbjct: 696 QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGE 755 Query: 510 RG------PVGPRGFP---------GLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS 554 +G P GP G+P G++G KGS G G G PG KGD+G G G G Sbjct: 756 KGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQ 815 Query: 555 PGP---SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 GP GP+G G AG TG PG G G KG+ G+ G PG PG GP GS F Sbjct: 816 IGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 869 Score = 133 bits (335), Expect = 4e-31 Identities = 72/147 (48%), Positives = 83/147 (56%), Gaps = 18/147 (12%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG---PVGERG 511 LRG PGP G +G G G GP G GP G PG G G +G +G PG G P GE+G Sbjct: 1421 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG 1480 Query: 512 PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTG 571 G RG PG +GS G+ G GG PGP G +GPP GPPG PGP GP+ G Sbjct: 1481 EKGDRGLPGTQGSPGAKGDGGI---PGPAGPLGPP---GPPGLPGPQGPK---------G 1525 Query: 572 SPGQRGAMGPKGEPGIQGPPGLPGPPG 598 + G G G KG+ G+ GPPG PGPPG Sbjct: 1526 NKGSTGPAGQKGDSGLPGPPGSPGPPG 1552 Score = 121 bits (303), Expect = 2e-27 Identities = 76/193 (39%), Positives = 87/193 (45%), Gaps = 48/193 (24%) Query: 454 ILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV------ 507 ++ G PGP GP G G G++GP GP GDPG GP G G G G GP Sbjct: 451 LVEGPPGPAGPAGIMGPPGLQGPT---GPPGDPGDRGPPGRPGLPGADGLPGPPGTMLML 507 Query: 508 -------GERGP-----------------VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDI 543 G +GP + RG PG G G G G G G KG+ Sbjct: 508 PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGES 567 Query: 544 GPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR---GAMGPKGEPGIQGPPGLP------ 594 G PGP+GP G GP GP GKPG G+ G+ G R G G KG+ G G PGLP Sbjct: 568 GDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHR 627 Query: 595 ------GPPGPPG 601 GPPGPPG Sbjct: 628 GERGPQGPPGPPG 640 Score = 110 bits (275), Expect = 4e-24 Identities = 71/183 (38%), Positives = 80/183 (43%), Gaps = 37/183 (20%) Query: 460 GPPGPRGFKGD-------MGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 G G +G KG+ M V+GP G GP G G G GP GP G PG+ GP G G Sbjct: 432 GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 491 Query: 513 VGPRGFPGLKGSK-------GSFGTGGP--------------------RGQPGPKGDIGP 545 G G PG G+ G G+ GP RG PGP G G Sbjct: 492 PGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGR 551 Query: 546 PGPEGPPGSPGPSGPQGKPGIAGKTG---SPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 PGP G PGS G G G PG G G PG G G +G PG G G+PG PG G Sbjct: 552 PGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGD 611 Query: 603 QSF 605 + F Sbjct: 612 RGF 614 Score = 101 bits (251), Expect = 2e-21 Identities = 54/120 (45%), Positives = 65/120 (54%), Gaps = 12/120 (10%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G GPPGP G G G+KG G +G KG PG +G +GP G QG+ G+ G G +G G + Sbjct: 1438 GQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAK 1497 Query: 517 GFPGLKGSKGSFGTGGPRGQPGP------KGDIGPPGPEG------PPGSPGPSGPQGKP 564 G G+ G G G GP G PGP KG GP G +G PPGSPGP G +P Sbjct: 1498 GDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQP 1557 Score = 91.3 bits (225), Expect = 2e-18 Identities = 48/97 (49%), Positives = 53/97 (54%), Gaps = 9/97 (9%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPVGERG 511 L G GPPG +G KGD G+ G G G KGD PG GPLGP GP G PG GP G +G Sbjct: 1469 LIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKG 1528 Query: 512 PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548 GP G KG G GP G PGP G++ P P Sbjct: 1529 STGPAG------QKGDSGLPGPPGSPGPPGEVIQPLP 1559 Score = 53.1 bits (126), Expect = 7e-07 Identities = 30/76 (39%), Positives = 34/76 (44%), Gaps = 18/76 (23%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQG------------------P 497 RG PG G G KGD G+ GP G GP G PG GP GP+G P Sbjct: 1485 RGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP 1544 Query: 498 QGQPGEAGPVGERGPV 513 G PG G V + P+ Sbjct: 1545 PGSPGPPGEVIQPLPI 1560 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 155 bits (392), Expect = 1e-37 Identities = 78/156 (50%), Positives = 90/156 (57%), Gaps = 12/156 (7%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L+G PGPPG +G GD+G GP G GP+G G G GPQGP G G G VGE+G G Sbjct: 1160 LQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG 1219 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS---PGPSGPQGKPGIAGKTG 571 G PG G G GGP+G+ G KG+ GPPG GPPG+ PG GP+G PG G G Sbjct: 1220 EAGNPG---PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPG 1276 Query: 572 SPGQRGAMGPKGEPGI------QGPPGLPGPPGPPG 601 PG G GP G+ G+ G PG PGPPGP G Sbjct: 1277 DPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSG 1312 Score = 152 bits (383), Expect = 1e-36 Identities = 78/147 (53%), Positives = 88/147 (59%), Gaps = 9/147 (6%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG PGPPGP G+ G+ G G G KGDP GP G G G G G GERG G Sbjct: 945 RGHPGPPGP---PGEQGLPGAAGKEGAKGDP---GPQGISGKDGPAGLRGFPGERGLPGA 998 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 +G PGLKG +G G GP G PG +G G GP G PG PGP GP PG AG+ G+PG+ Sbjct: 999 QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGP---PGPAGEKGAPGE 1055 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPGS 602 +G GP G G+QGP GLPGP GP GS Sbjct: 1056 KGPQGPAGRDGVQGPVGLPGPAGPAGS 1082 Score = 152 bits (383), Expect = 1e-36 Identities = 78/156 (50%), Positives = 88/156 (56%), Gaps = 12/156 (7%) Query: 457 GAPGPPGPRGFKGDMGVKGP---------VGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV 507 G PGPPGPRG +G G GP VGG G KG+PG G GP G G G G Sbjct: 1180 GPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGER 1239 Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA 567 GE+G GP G G G+KG G GP+G PGP +G PG GPPG PGP+G G G Sbjct: 1240 GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGP---VGFPGDPGPPGEPGPAGQDGVGGDK 1296 Query: 568 GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G+ G PGQ G GP GE G GPPG GPPG G++ Sbjct: 1297 GEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1332 Score = 150 bits (380), Expect = 2e-36 Identities = 78/148 (52%), Positives = 89/148 (60%), Gaps = 9/148 (6%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG G PG G KG G +GP G GP GD G G G GP+G PGEAGP RG +GP Sbjct: 561 RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGP---RGLLGP 617 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 RG PG G G G GP PGPKG++GP G GPPG G GPQG PG G G PG+ Sbjct: 618 RGTPGAPGQPGMAGVDGP---PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGE 674 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 + GP+G+PG+ G PG GPPG PG + Sbjct: 675 K---GPQGKPGLAGLPGADGPPGHPGKE 699 Score = 150 bits (380), Expect = 2e-36 Identities = 81/167 (48%), Positives = 93/167 (55%), Gaps = 18/167 (10%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLG------PQGPQGQPGEAGPVG 508 L GA G PG +G +G G GPVG G +G G+ GP+G PQGP G GE G G Sbjct: 995 LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1054 Query: 509 ERGPVGPRGFPGLKGSKGSFGTGGPRGQP---GPKGDIGPPGPE---------GPPGSPG 556 E+GP GP G G++G G G GP G P G KG+IG PG + GPPG PG Sbjct: 1055 EKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG 1114 Query: 557 PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 GP G PGIAG G PG RG G G+ G +G G PGPPGP G Q Sbjct: 1115 LQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ 1161 Score = 150 bits (379), Expect = 3e-36 Identities = 78/160 (48%), Positives = 94/160 (58%), Gaps = 12/160 (7%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVG--GR-------GPKGDPGSLGPLGPQGPQGQPGEAGP 506 +G PGP G G +G G GP+G GR GP G+ G+ G GPQGP G+ G GP Sbjct: 1011 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1070 Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP---EGPPGSPGPSGPQGK 563 VG GP GP G PG G KG G G +G G KG+ GPPGP +GP G+PG +G G+ Sbjct: 1071 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGE 1130 Query: 564 PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 PG G+ G GQ+G G +G PG GP GL G PGPPG + Sbjct: 1131 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1170 Score = 149 bits (376), Expect = 7e-36 Identities = 75/145 (51%), Positives = 85/145 (58%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G GPPG G +G G KG G G +G PG GP+GPQGP G+PG G G GPVG + Sbjct: 1321 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1380 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G PG G G G GP G PG KGD G G +G PG G GP G+ G G G PG + Sbjct: 1381 GLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1440 Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPG 601 G+ G KG+ GI GP G GPPGPPG Sbjct: 1441 GSPGAKGDGGIPGPAGPLGPPGPPG 1465 Score = 147 bits (371), Expect = 3e-35 Identities = 79/168 (47%), Positives = 93/168 (55%), Gaps = 4/168 (2%) Query: 438 MKAVDTQHGEILRNVTI-LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQG 496 + A + Q IL+ I LRG PGP G G G +G G G +G GDPG GP G QG Sbjct: 470 ISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQG 529 Query: 497 PQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPG 556 P G G+ G G G G RG PG G+KG G G G PG KG G GP+GPPG PG Sbjct: 530 PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 589 Query: 557 PSGPQGKPGIAGKTGSPGQ---RGAMGPKGEPGIQGPPGLPGPPGPPG 601 G +G+ G G G PG+ RG +GP+G PG G PG+ G GPPG Sbjct: 590 DDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 637 Score = 146 bits (369), Expect = 5e-35 Identities = 73/146 (50%), Positives = 82/146 (56%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +G PG G G G+ GV GP G RG KG+ G G GP G +G PG+ GP G GPVG Sbjct: 1215 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1274 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 G PG G G G G G G GD G PGP GP G GP GP GK G G G+ G+ Sbjct: 1275 PGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGR 1334 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPG 601 +G G KGE G +GPPG GP GP G Sbjct: 1335 QGEKGAKGEAGAEGPPGKTGPVGPQG 1360 Score = 145 bits (366), Expect = 1e-34 Identities = 76/170 (44%), Positives = 90/170 (52%), Gaps = 24/170 (14%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG---ERGP 512 RG PG PG G G G GP G GP+G+PG G G GPQG PG GP+G E+GP Sbjct: 618 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 677 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572 G G GL G+ G G G GQ G KG +GPPGP+GP G PGP G +G G+ G GS Sbjct: 678 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 737 Query: 573 PGQR---------------------GAMGPKGEPGIQGPPGLPGPPGPPG 601 G++ G +GP+GE G +GP G GP G PG Sbjct: 738 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 787 Score = 144 bits (364), Expect = 2e-34 Identities = 84/174 (48%), Positives = 94/174 (54%), Gaps = 27/174 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGPVG--GR-GPKGD---PGSLGPLGPQGPQGQPGEAGPVGER 510 G PGP G G KG +GV G G GR GPKG PG G G +G +G G+ GP G+R Sbjct: 784 GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 843 Query: 511 GPVGPRGFPGLKGSKGS---FGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP--- 564 GP GPRG G +G G GT G G PGP G+ GP GP+GP G PGP GP G P Sbjct: 844 GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 903 Query: 565 ------------GIAGKTGSPGQRGAMGPKGEPGIQGP---PGLPGPPGPPGSQ 603 G GKTG PG G +GP+G G GP G PGPPGPPG Q Sbjct: 904 GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQ 957 Score = 144 bits (364), Expect = 2e-34 Identities = 82/189 (43%), Positives = 93/189 (49%), Gaps = 42/189 (22%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG- 514 RG G PGPRG +G G +G G RGP G PG G G GP G PGE GP G +GPVG Sbjct: 831 RGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGF 890 Query: 515 --PRG---------FPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------PGS 554 P+G PG G +G G G G PGP G +GP GP G PG Sbjct: 891 PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 950 Query: 555 PGPSGPQGKPGIAGKTGS---------------------PGQRGAMGPKGEPGIQGPPGL 593 PGP G QG PG AGK G+ PG+RG G +G PG++G G Sbjct: 951 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1010 Query: 594 PGPPGPPGS 602 GPPGP GS Sbjct: 1011 QGPPGPVGS 1019 Score = 144 bits (364), Expect = 2e-34 Identities = 74/150 (49%), Positives = 86/150 (57%), Gaps = 6/150 (4%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 + G GP G RGF G+ G+ G G G KG G P GP GP G PGE G G GP+G Sbjct: 977 ISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEG---PQGPPGPVGSPGERGSAGTAGPIG 1033 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP---GIAGKTG 571 G PG +G G G G G+ GP+G G G +GP G PGP+GP G P G G+ G Sbjct: 1034 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG 1093 Query: 572 SPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 PGQ+G+ G KGE G GPPGL GP G PG Sbjct: 1094 EPGQKGSKGDKGENGPPGPPGLQGPVGAPG 1123 Score = 144 bits (363), Expect = 2e-34 Identities = 78/159 (49%), Positives = 87/159 (54%), Gaps = 12/159 (7%) Query: 457 GAPGPPG------PRGFKGDMGVKGPVGGRGP---KGDPGSLGPLGPQGPQGQPGEAGPV 507 G PGPPG P+G +G+ G GP G GP KG PG GP G GP G PG+ GP Sbjct: 1222 GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP 1281 Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI- 566 GE GP G G G KG G G GP G G G GPPG GPPG+ G G QG+ G Sbjct: 1282 GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAK 1341 Query: 567 --AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 AG G PG+ G +GP+G G GP GL G PGP G Q Sbjct: 1342 GEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1380 Score = 143 bits (360), Expect = 5e-34 Identities = 75/164 (45%), Positives = 88/164 (53%), Gaps = 18/164 (10%) Query: 456 RGAPGPPGPRGFKGDMGVKGP---VGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG- 511 +G G G GFKGDMG+KG VG GP+G+ G GP G GP G PG +G GE+G Sbjct: 738 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 797 Query: 512 --------------PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP 557 P G GFPG G+ G G G G+PGP+G GP GP G G+ GP Sbjct: 798 LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 857 Query: 558 SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 +G G G +G G PG G GP+G G G PG GPPGPPG Sbjct: 858 TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPG 901 Score = 142 bits (359), Expect = 7e-34 Identities = 77/156 (49%), Positives = 92/156 (58%), Gaps = 12/156 (7%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP---LGPQGPQGQPGEAGPVGERGP 512 RG GP GP G GD G++G G GP+G PG GP LGP+G G PG+ G G GP Sbjct: 576 RGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP 635 Query: 513 VGPRGFPGLKGSKG---SFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS---GPQGKPGI 566 GP+G G +G G G GP+G PGP+G IGPPG +GP G PG + G G PG Sbjct: 636 PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 695 Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 GK G G++GA+GP PG QGP G PGP G G+ Sbjct: 696 PGKEGQSGEKGALGP---PGPQGPIGYPGPRGVKGA 728 Score = 142 bits (359), Expect = 7e-34 Identities = 83/186 (44%), Positives = 94/186 (50%), Gaps = 39/186 (20%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGG---RGPKGDPGSLGPLGP---QGPQGQPGEAGPVGER 510 G PGP GP G G+ G KG +G +G KGD G GP GP QGP G PG AG GE Sbjct: 1072 GLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEP 1131 Query: 511 GP------------VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS 558 GP G RGFPG G G G GP G+ G GD+GP GP GPPG GP Sbjct: 1132 GPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ 1191 Query: 559 GP---------------------QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP 597 GP +G+PG AG G PG+ G GPKGE G +G G PG Sbjct: 1192 GPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAA 1251 Query: 598 GPPGSQ 603 GPPG++ Sbjct: 1252 GPPGAK 1257 Score = 141 bits (356), Expect = 2e-33 Identities = 77/156 (49%), Positives = 91/156 (58%), Gaps = 9/156 (5%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +GAPG GP+G G GV+GPVG GP G GS G G +G G+PG+ G G++G GP Sbjct: 1050 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP 1109 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP------PGSPGPSGPQGKPGIAGK 569 G PGL+G G+ G G G+PGP+G G G +G PG PGP G QG PG G+ Sbjct: 1110 PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1169 Query: 570 TGSPGQRGAMGPKGEP---GIQGPPGLPGPPGPPGS 602 G G G MGP G P G QGP G GP GPPGS Sbjct: 1170 KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGS 1205 Score = 141 bits (356), Expect = 2e-33 Identities = 77/165 (46%), Positives = 84/165 (50%), Gaps = 18/165 (10%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQ------------PGEA 504 G PG GP G KG G GP G GP G PG GP G GP GQ PG+ Sbjct: 1246 GPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP 1305 Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564 GP G G GP G PG +G G+ G G +G+ G KG+ G GP G G GP GP GKP Sbjct: 1306 GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1365 Query: 565 ------GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 GI G G G GA G G PG GPPGLPG G PGS+ Sbjct: 1366 GPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSK 1410 Score = 141 bits (355), Expect = 2e-33 Identities = 72/154 (46%), Positives = 87/154 (56%), Gaps = 6/154 (3%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 + G G PGPRG +G G KG G RG G PG P+G QG G PGE G G+ GP+G Sbjct: 1124 IAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG---PIGLQGLPGPPGEKGENGDVGPMG 1180 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574 P G PG +G +G G GP+G PG G +G G +G PG G GP G+ G+ G G G Sbjct: 1181 PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERG 1240 Query: 575 QRGAMGPKGE---PGIQGPPGLPGPPGPPGSQSF 605 ++G GP G PG +GPPG GP G PG F Sbjct: 1241 EKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1274 Score = 140 bits (354), Expect = 3e-33 Identities = 72/156 (46%), Positives = 85/156 (54%), Gaps = 6/156 (3%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G G PG RG G G G GG GP+G PG +G G +G G G G G GP GP Sbjct: 985 GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPP 1044 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G G KG+ G G GP G+ G +G +G PGP GP GSPG G +G+ G G+ GS G + Sbjct: 1045 GPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDK 1104 Query: 577 GAMGPKGEPGIQGPPGLP------GPPGPPGSQSFY 606 G GP G PG+QGP G P G PGP G Q + Sbjct: 1105 GENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMF 1140 Score = 140 bits (353), Expect = 3e-33 Identities = 75/148 (50%), Positives = 81/148 (54%), Gaps = 6/148 (4%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG PGP G G G G G +G GDPG GP GP G G PG G G G G Sbjct: 1273 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1332 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGP---PGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 G G KG+KG G GP G+ GP G GP PGPEG G PGP G QG PG AG+ G P Sbjct: 1333 GRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1392 Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G MGP G PG++G PG G G PG Sbjct: 1393 ---GPMGPPGLPGLKGDPGSKGEKGHPG 1417 Score = 139 bits (349), Expect = 1e-32 Identities = 77/171 (45%), Positives = 95/171 (55%), Gaps = 24/171 (14%) Query: 457 GAPGP------PGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPV 507 G PGP PGPRG KG GV+G G +G KG+ PG G +G +G +G+ G+ GP Sbjct: 709 GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 768 Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP------PGSPGPSGPQ 561 GE GP GP+G G G G G G +G+ G G G PG +GP PG PG +G + Sbjct: 769 GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 828 Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP---------GPPGPPGSQ 603 G G+AGK G GQRG GP+G G +GP G P GPPGPPG + Sbjct: 829 GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 879 Score = 137 bits (346), Expect = 2e-32 Identities = 81/169 (47%), Positives = 85/169 (50%), Gaps = 21/169 (12%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGPVG- 508 RG+ G GP G G G +GP G G KG PG GP GP QGP G PG AGP G Sbjct: 1023 RGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1082 Query: 509 --ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGK--- 563 E G G G PG KGSKG G GP G PG +G +G PG G G PGP G QG Sbjct: 1083 PGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQ 1142 Query: 564 ---------PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 PG G G G G G KGE G GP G PGPPGP G Q Sbjct: 1143 KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ 1191 Score = 137 bits (344), Expect = 4e-32 Identities = 75/164 (45%), Positives = 88/164 (53%), Gaps = 21/164 (12%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +G G GP G G +G +GP G GP+G G GP+ G QG PG AG G GP+GP Sbjct: 1341 KGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV---GEQGLPGAAGQDGPPGPMGP 1397 Query: 516 RGFPGLKGSKGS---------FGTGGPRGQPGPKGDIGPPGPEGPPGS---------PGP 557 G PGLKG GS G GP G+ G KGD G PG +G PG+ GP Sbjct: 1398 PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGP 1457 Query: 558 SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 GP G PG+ G G G +G+ GP G+ G G PG PG PGPPG Sbjct: 1458 LGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1501 Score = 136 bits (343), Expect = 5e-32 Identities = 78/174 (44%), Positives = 91/174 (52%), Gaps = 24/174 (13%) Query: 456 RGAPGPPG------PRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509 +G PGPPG P+G G G GP G +GP+G PG G G GP G PG+ G GE Sbjct: 645 QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGE 704 Query: 510 RG------PVGPRGFP---------GLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS 554 +G P GP G+P G++G KGS G G G PG KGD+G G G G Sbjct: 705 KGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQ 764 Query: 555 PGP---SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 GP GP+G G AG TG PG G G KG+ G+ G PG PG GP GS F Sbjct: 765 IGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 818 Score = 133 bits (335), Expect = 4e-31 Identities = 72/147 (48%), Positives = 83/147 (56%), Gaps = 18/147 (12%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG---PVGERG 511 LRG PGP G +G G G GP G GP G PG G G +G +G PG G P GE+G Sbjct: 1370 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG 1429 Query: 512 PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTG 571 G RG PG +GS G+ G GG PGP G +GPP GPPG PGP GP+ G Sbjct: 1430 EKGDRGLPGTQGSPGAKGDGGI---PGPAGPLGPP---GPPGLPGPQGPK---------G 1474 Query: 572 SPGQRGAMGPKGEPGIQGPPGLPGPPG 598 + G G G KG+ G+ GPPG PGPPG Sbjct: 1475 NKGSTGPAGQKGDSGLPGPPGSPGPPG 1501 Score = 121 bits (303), Expect = 2e-27 Identities = 76/193 (39%), Positives = 87/193 (45%), Gaps = 48/193 (24%) Query: 454 ILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV------ 507 ++ G PGP GP G G G++GP GP GDPG GP G G G G GP Sbjct: 400 LVEGPPGPAGPAGIMGPPGLQGPT---GPPGDPGDRGPPGRPGLPGADGLPGPPGTMLML 456 Query: 508 -------GERGP-----------------VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDI 543 G +GP + RG PG G G G G G G KG+ Sbjct: 457 PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGES 516 Query: 544 GPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR---GAMGPKGEPGIQGPPGLP------ 594 G PGP+GP G GP GP GKPG G+ G+ G R G G KG+ G G PGLP Sbjct: 517 GDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHR 576 Query: 595 ------GPPGPPG 601 GPPGPPG Sbjct: 577 GERGPQGPPGPPG 589 Score = 110 bits (275), Expect = 4e-24 Identities = 71/183 (38%), Positives = 80/183 (43%), Gaps = 37/183 (20%) Query: 460 GPPGPRGFKGD-------MGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 G G +G KG+ M V+GP G GP G G G GP GP G PG+ GP G G Sbjct: 381 GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 440 Query: 513 VGPRGFPGLKGSK-------GSFGTGGP--------------------RGQPGPKGDIGP 545 G G PG G+ G G+ GP RG PGP G G Sbjct: 441 PGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGR 500 Query: 546 PGPEGPPGSPGPSGPQGKPGIAGKTG---SPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 PGP G PGS G G G PG G G PG G G +G PG G G+PG PG G Sbjct: 501 PGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGD 560 Query: 603 QSF 605 + F Sbjct: 561 RGF 563 Score = 101 bits (251), Expect = 2e-21 Identities = 54/120 (45%), Positives = 65/120 (54%), Gaps = 12/120 (10%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G GPPGP G G G+KG G +G KG PG +G +GP G QG+ G+ G G +G G + Sbjct: 1387 GQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAK 1446 Query: 517 GFPGLKGSKGSFGTGGPRGQPGP------KGDIGPPGPEG------PPGSPGPSGPQGKP 564 G G+ G G G GP G PGP KG GP G +G PPGSPGP G +P Sbjct: 1447 GDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQP 1506 Score = 91.3 bits (225), Expect = 2e-18 Identities = 48/97 (49%), Positives = 53/97 (54%), Gaps = 9/97 (9%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPVGERG 511 L G GPPG +G KGD G+ G G G KGD PG GPLGP GP G PG GP G +G Sbjct: 1418 LIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKG 1477 Query: 512 PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548 GP G KG G GP G PGP G++ P P Sbjct: 1478 STGPAG------QKGDSGLPGPPGSPGPPGEVIQPLP 1508 Score = 53.1 bits (126), Expect = 7e-07 Identities = 30/76 (39%), Positives = 34/76 (44%), Gaps = 18/76 (23%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQG------------------P 497 RG PG G G KGD G+ GP G GP G PG GP GP+G P Sbjct: 1434 RGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP 1493 Query: 498 QGQPGEAGPVGERGPV 513 G PG G V + P+ Sbjct: 1494 PGSPGPPGEVIQPLPI 1509 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 155 bits (392), Expect = 1e-37 Identities = 78/156 (50%), Positives = 90/156 (57%), Gaps = 12/156 (7%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L+G PGPPG +G GD+G GP G GP+G G G GPQGP G G G VGE+G G Sbjct: 1199 LQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG 1258 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS---PGPSGPQGKPGIAGKTG 571 G PG G G GGP+G+ G KG+ GPPG GPPG+ PG GP+G PG G G Sbjct: 1259 EAGNPG---PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPG 1315 Query: 572 SPGQRGAMGPKGEPGI------QGPPGLPGPPGPPG 601 PG G GP G+ G+ G PG PGPPGP G Sbjct: 1316 DPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSG 1351 Score = 152 bits (383), Expect = 1e-36 Identities = 78/147 (53%), Positives = 88/147 (59%), Gaps = 9/147 (6%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG PGPPGP G+ G+ G G G KGDP GP G G G G G GERG G Sbjct: 984 RGHPGPPGP---PGEQGLPGAAGKEGAKGDP---GPQGISGKDGPAGLRGFPGERGLPGA 1037 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 +G PGLKG +G G GP G PG +G G GP G PG PGP GP PG AG+ G+PG+ Sbjct: 1038 QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGP---PGPAGEKGAPGE 1094 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPGS 602 +G GP G G+QGP GLPGP GP GS Sbjct: 1095 KGPQGPAGRDGVQGPVGLPGPAGPAGS 1121 Score = 152 bits (383), Expect = 1e-36 Identities = 78/156 (50%), Positives = 88/156 (56%), Gaps = 12/156 (7%) Query: 457 GAPGPPGPRGFKGDMGVKGP---------VGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV 507 G PGPPGPRG +G G GP VGG G KG+PG G GP G G G G Sbjct: 1219 GPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGER 1278 Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA 567 GE+G GP G G G+KG G GP+G PGP +G PG GPPG PGP+G G G Sbjct: 1279 GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGP---VGFPGDPGPPGEPGPAGQDGVGGDK 1335 Query: 568 GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G+ G PGQ G GP GE G GPPG GPPG G++ Sbjct: 1336 GEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1371 Score = 150 bits (380), Expect = 2e-36 Identities = 78/148 (52%), Positives = 89/148 (60%), Gaps = 9/148 (6%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG G PG G KG G +GP G GP GD G G G GP+G PGEAGP RG +GP Sbjct: 600 RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGP---RGLLGP 656 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 RG PG G G G GP PGPKG++GP G GPPG G GPQG PG G G PG+ Sbjct: 657 RGTPGAPGQPGMAGVDGP---PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGE 713 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 + GP+G+PG+ G PG GPPG PG + Sbjct: 714 K---GPQGKPGLAGLPGADGPPGHPGKE 738 Score = 150 bits (380), Expect = 2e-36 Identities = 81/167 (48%), Positives = 93/167 (55%), Gaps = 18/167 (10%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLG------PQGPQGQPGEAGPVG 508 L GA G PG +G +G G GPVG G +G G+ GP+G PQGP G GE G G Sbjct: 1034 LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1093 Query: 509 ERGPVGPRGFPGLKGSKGSFGTGGPRGQP---GPKGDIGPPGPE---------GPPGSPG 556 E+GP GP G G++G G G GP G P G KG+IG PG + GPPG PG Sbjct: 1094 EKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG 1153 Query: 557 PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 GP G PGIAG G PG RG G G+ G +G G PGPPGP G Q Sbjct: 1154 LQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ 1200 Score = 150 bits (379), Expect = 3e-36 Identities = 78/160 (48%), Positives = 94/160 (58%), Gaps = 12/160 (7%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVG--GR-------GPKGDPGSLGPLGPQGPQGQPGEAGP 506 +G PGP G G +G G GP+G GR GP G+ G+ G GPQGP G+ G GP Sbjct: 1050 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1109 Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP---EGPPGSPGPSGPQGK 563 VG GP GP G PG G KG G G +G G KG+ GPPGP +GP G+PG +G G+ Sbjct: 1110 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGE 1169 Query: 564 PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 PG G+ G GQ+G G +G PG GP GL G PGPPG + Sbjct: 1170 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1209 Score = 149 bits (376), Expect = 7e-36 Identities = 75/145 (51%), Positives = 85/145 (58%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G GPPG G +G G KG G G +G PG GP+GPQGP G+PG G G GPVG + Sbjct: 1360 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1419 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G PG G G G GP G PG KGD G G +G PG G GP G+ G G G PG + Sbjct: 1420 GLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1479 Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPG 601 G+ G KG+ GI GP G GPPGPPG Sbjct: 1480 GSPGAKGDGGIPGPAGPLGPPGPPG 1504 Score = 147 bits (371), Expect = 3e-35 Identities = 79/168 (47%), Positives = 93/168 (55%), Gaps = 4/168 (2%) Query: 438 MKAVDTQHGEILRNVTI-LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQG 496 + A + Q IL+ I LRG PGP G G G +G G G +G GDPG GP G QG Sbjct: 509 ISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQG 568 Query: 497 PQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPG 556 P G G+ G G G G RG PG G+KG G G G PG KG G GP+GPPG PG Sbjct: 569 PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 628 Query: 557 PSGPQGKPGIAGKTGSPGQ---RGAMGPKGEPGIQGPPGLPGPPGPPG 601 G +G+ G G G PG+ RG +GP+G PG G PG+ G GPPG Sbjct: 629 DDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 676 Score = 146 bits (369), Expect = 5e-35 Identities = 73/146 (50%), Positives = 82/146 (56%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +G PG G G G+ GV GP G RG KG+ G G GP G +G PG+ GP G GPVG Sbjct: 1254 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1313 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 G PG G G G G G G GD G PGP GP G GP GP GK G G G+ G+ Sbjct: 1314 PGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGR 1373 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPG 601 +G G KGE G +GPPG GP GP G Sbjct: 1374 QGEKGAKGEAGAEGPPGKTGPVGPQG 1399 Score = 145 bits (366), Expect = 1e-34 Identities = 76/170 (44%), Positives = 90/170 (52%), Gaps = 24/170 (14%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG---ERGP 512 RG PG PG G G G GP G GP+G+PG G G GPQG PG GP+G E+GP Sbjct: 657 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 716 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572 G G GL G+ G G G GQ G KG +GPPGP+GP G PGP G +G G+ G GS Sbjct: 717 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 776 Query: 573 PGQR---------------------GAMGPKGEPGIQGPPGLPGPPGPPG 601 G++ G +GP+GE G +GP G GP G PG Sbjct: 777 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 826 Score = 144 bits (364), Expect = 2e-34 Identities = 84/174 (48%), Positives = 94/174 (54%), Gaps = 27/174 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGPVG--GR-GPKGD---PGSLGPLGPQGPQGQPGEAGPVGER 510 G PGP G G KG +GV G G GR GPKG PG G G +G +G G+ GP G+R Sbjct: 823 GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 882 Query: 511 GPVGPRGFPGLKGSKGS---FGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP--- 564 GP GPRG G +G G GT G G PGP G+ GP GP+GP G PGP GP G P Sbjct: 883 GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 942 Query: 565 ------------GIAGKTGSPGQRGAMGPKGEPGIQGP---PGLPGPPGPPGSQ 603 G GKTG PG G +GP+G G GP G PGPPGPPG Q Sbjct: 943 GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQ 996 Score = 144 bits (364), Expect = 2e-34 Identities = 82/189 (43%), Positives = 93/189 (49%), Gaps = 42/189 (22%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG- 514 RG G PGPRG +G G +G G RGP G PG G G GP G PGE GP G +GPVG Sbjct: 870 RGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGF 929 Query: 515 --PRG---------FPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------PGS 554 P+G PG G +G G G G PGP G +GP GP G PG Sbjct: 930 PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 989 Query: 555 PGPSGPQGKPGIAGKTGS---------------------PGQRGAMGPKGEPGIQGPPGL 593 PGP G QG PG AGK G+ PG+RG G +G PG++G G Sbjct: 990 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1049 Query: 594 PGPPGPPGS 602 GPPGP GS Sbjct: 1050 QGPPGPVGS 1058 Score = 144 bits (364), Expect = 2e-34 Identities = 74/150 (49%), Positives = 86/150 (57%), Gaps = 6/150 (4%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 + G GP G RGF G+ G+ G G G KG G P GP GP G PGE G G GP+G Sbjct: 1016 ISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEG---PQGPPGPVGSPGERGSAGTAGPIG 1072 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP---GIAGKTG 571 G PG +G G G G G+ GP+G G G +GP G PGP+GP G P G G+ G Sbjct: 1073 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG 1132 Query: 572 SPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 PGQ+G+ G KGE G GPPGL GP G PG Sbjct: 1133 EPGQKGSKGDKGENGPPGPPGLQGPVGAPG 1162 Score = 144 bits (363), Expect = 2e-34 Identities = 78/159 (49%), Positives = 87/159 (54%), Gaps = 12/159 (7%) Query: 457 GAPGPPG------PRGFKGDMGVKGPVGGRGP---KGDPGSLGPLGPQGPQGQPGEAGPV 507 G PGPPG P+G +G+ G GP G GP KG PG GP G GP G PG+ GP Sbjct: 1261 GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP 1320 Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI- 566 GE GP G G G KG G G GP G G G GPPG GPPG+ G G QG+ G Sbjct: 1321 GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAK 1380 Query: 567 --AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 AG G PG+ G +GP+G G GP GL G PGP G Q Sbjct: 1381 GEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1419 Score = 143 bits (360), Expect = 5e-34 Identities = 75/164 (45%), Positives = 88/164 (53%), Gaps = 18/164 (10%) Query: 456 RGAPGPPGPRGFKGDMGVKGP---VGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG- 511 +G G G GFKGDMG+KG VG GP+G+ G GP G GP G PG +G GE+G Sbjct: 777 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 836 Query: 512 --------------PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP 557 P G GFPG G+ G G G G+PGP+G GP GP G G+ GP Sbjct: 837 LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 896 Query: 558 SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 +G G G +G G PG G GP+G G G PG GPPGPPG Sbjct: 897 TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPG 940 Score = 142 bits (359), Expect = 7e-34 Identities = 77/156 (49%), Positives = 92/156 (58%), Gaps = 12/156 (7%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP---LGPQGPQGQPGEAGPVGERGP 512 RG GP GP G GD G++G G GP+G PG GP LGP+G G PG+ G G GP Sbjct: 615 RGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP 674 Query: 513 VGPRGFPGLKGSKG---SFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS---GPQGKPGI 566 GP+G G +G G G GP+G PGP+G IGPPG +GP G PG + G G PG Sbjct: 675 PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 734 Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 GK G G++GA+GP PG QGP G PGP G G+ Sbjct: 735 PGKEGQSGEKGALGP---PGPQGPIGYPGPRGVKGA 767 Score = 142 bits (359), Expect = 7e-34 Identities = 83/186 (44%), Positives = 94/186 (50%), Gaps = 39/186 (20%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGG---RGPKGDPGSLGPLGP---QGPQGQPGEAGPVGER 510 G PGP GP G G+ G KG +G +G KGD G GP GP QGP G PG AG GE Sbjct: 1111 GLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEP 1170 Query: 511 GP------------VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS 558 GP G RGFPG G G G GP G+ G GD+GP GP GPPG GP Sbjct: 1171 GPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ 1230 Query: 559 GP---------------------QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP 597 GP +G+PG AG G PG+ G GPKGE G +G G PG Sbjct: 1231 GPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAA 1290 Query: 598 GPPGSQ 603 GPPG++ Sbjct: 1291 GPPGAK 1296 Score = 141 bits (356), Expect = 2e-33 Identities = 77/156 (49%), Positives = 91/156 (58%), Gaps = 9/156 (5%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +GAPG GP+G G GV+GPVG GP G GS G G +G G+PG+ G G++G GP Sbjct: 1089 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP 1148 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP------PGSPGPSGPQGKPGIAGK 569 G PGL+G G+ G G G+PGP+G G G +G PG PGP G QG PG G+ Sbjct: 1149 PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1208 Query: 570 TGSPGQRGAMGPKGEP---GIQGPPGLPGPPGPPGS 602 G G G MGP G P G QGP G GP GPPGS Sbjct: 1209 KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGS 1244 Score = 141 bits (356), Expect = 2e-33 Identities = 77/165 (46%), Positives = 84/165 (50%), Gaps = 18/165 (10%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQ------------PGEA 504 G PG GP G KG G GP G GP G PG GP G GP GQ PG+ Sbjct: 1285 GPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP 1344 Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564 GP G G GP G PG +G G+ G G +G+ G KG+ G GP G G GP GP GKP Sbjct: 1345 GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1404 Query: 565 ------GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 GI G G G GA G G PG GPPGLPG G PGS+ Sbjct: 1405 GPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSK 1449 Score = 141 bits (355), Expect = 2e-33 Identities = 72/154 (46%), Positives = 87/154 (56%), Gaps = 6/154 (3%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 + G G PGPRG +G G KG G RG G PG P+G QG G PGE G G+ GP+G Sbjct: 1163 IAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG---PIGLQGLPGPPGEKGENGDVGPMG 1219 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574 P G PG +G +G G GP+G PG G +G G +G PG G GP G+ G+ G G G Sbjct: 1220 PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERG 1279 Query: 575 QRGAMGPKGE---PGIQGPPGLPGPPGPPGSQSF 605 ++G GP G PG +GPPG GP G PG F Sbjct: 1280 EKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1313 Score = 140 bits (354), Expect = 3e-33 Identities = 72/156 (46%), Positives = 85/156 (54%), Gaps = 6/156 (3%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G G PG RG G G G GG GP+G PG +G G +G G G G G GP GP Sbjct: 1024 GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPP 1083 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G G KG+ G G GP G+ G +G +G PGP GP GSPG G +G+ G G+ GS G + Sbjct: 1084 GPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDK 1143 Query: 577 GAMGPKGEPGIQGPPGLP------GPPGPPGSQSFY 606 G GP G PG+QGP G P G PGP G Q + Sbjct: 1144 GENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMF 1179 Score = 140 bits (353), Expect = 3e-33 Identities = 75/148 (50%), Positives = 81/148 (54%), Gaps = 6/148 (4%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG PGP G G G G G +G GDPG GP GP G G PG G G G G Sbjct: 1312 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1371 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGP---PGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 G G KG+KG G GP G+ GP G GP PGPEG G PGP G QG PG AG+ G P Sbjct: 1372 GRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1431 Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G MGP G PG++G PG G G PG Sbjct: 1432 ---GPMGPPGLPGLKGDPGSKGEKGHPG 1456 Score = 139 bits (349), Expect = 1e-32 Identities = 77/171 (45%), Positives = 95/171 (55%), Gaps = 24/171 (14%) Query: 457 GAPGP------PGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPV 507 G PGP PGPRG KG GV+G G +G KG+ PG G +G +G +G+ G+ GP Sbjct: 748 GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 807 Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP------PGSPGPSGPQ 561 GE GP GP+G G G G G G +G+ G G G PG +GP PG PG +G + Sbjct: 808 GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 867 Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP---------GPPGPPGSQ 603 G G+AGK G GQRG GP+G G +GP G P GPPGPPG + Sbjct: 868 GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 918 Score = 137 bits (346), Expect = 2e-32 Identities = 81/169 (47%), Positives = 85/169 (50%), Gaps = 21/169 (12%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGPVG- 508 RG+ G GP G G G +GP G G KG PG GP GP QGP G PG AGP G Sbjct: 1062 RGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1121 Query: 509 --ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGK--- 563 E G G G PG KGSKG G GP G PG +G +G PG G G PGP G QG Sbjct: 1122 PGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQ 1181 Query: 564 ---------PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 PG G G G G G KGE G GP G PGPPGP G Q Sbjct: 1182 KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ 1230 Score = 137 bits (344), Expect = 4e-32 Identities = 75/164 (45%), Positives = 88/164 (53%), Gaps = 21/164 (12%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +G G GP G G +G +GP G GP+G G GP+ G QG PG AG G GP+GP Sbjct: 1380 KGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV---GEQGLPGAAGQDGPPGPMGP 1436 Query: 516 RGFPGLKGSKGS---------FGTGGPRGQPGPKGDIGPPGPEGPPGS---------PGP 557 G PGLKG GS G GP G+ G KGD G PG +G PG+ GP Sbjct: 1437 PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGP 1496 Query: 558 SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 GP G PG+ G G G +G+ GP G+ G G PG PG PGPPG Sbjct: 1497 LGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1540 Score = 136 bits (343), Expect = 5e-32 Identities = 78/174 (44%), Positives = 91/174 (52%), Gaps = 24/174 (13%) Query: 456 RGAPGPPG------PRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509 +G PGPPG P+G G G GP G +GP+G PG G G GP G PG+ G GE Sbjct: 684 QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGE 743 Query: 510 RG------PVGPRGFP---------GLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS 554 +G P GP G+P G++G KGS G G G PG KGD+G G G G Sbjct: 744 KGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQ 803 Query: 555 PGP---SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 GP GP+G G AG TG PG G G KG+ G+ G PG PG GP GS F Sbjct: 804 IGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 857 Score = 133 bits (335), Expect = 4e-31 Identities = 72/147 (48%), Positives = 83/147 (56%), Gaps = 18/147 (12%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG---PVGERG 511 LRG PGP G +G G G GP G GP G PG G G +G +G PG G P GE+G Sbjct: 1409 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG 1468 Query: 512 PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTG 571 G RG PG +GS G+ G GG PGP G +GPP GPPG PGP GP+ G Sbjct: 1469 EKGDRGLPGTQGSPGAKGDGGI---PGPAGPLGPP---GPPGLPGPQGPK---------G 1513 Query: 572 SPGQRGAMGPKGEPGIQGPPGLPGPPG 598 + G G G KG+ G+ GPPG PGPPG Sbjct: 1514 NKGSTGPAGQKGDSGLPGPPGSPGPPG 1540 Score = 121 bits (303), Expect = 2e-27 Identities = 76/193 (39%), Positives = 87/193 (45%), Gaps = 48/193 (24%) Query: 454 ILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV------ 507 ++ G PGP GP G G G++GP GP GDPG GP G G G G GP Sbjct: 439 LVEGPPGPAGPAGIMGPPGLQGPT---GPPGDPGDRGPPGRPGLPGADGLPGPPGTMLML 495 Query: 508 -------GERGP-----------------VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDI 543 G +GP + RG PG G G G G G G KG+ Sbjct: 496 PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGES 555 Query: 544 GPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR---GAMGPKGEPGIQGPPGLP------ 594 G PGP+GP G GP GP GKPG G+ G+ G R G G KG+ G G PGLP Sbjct: 556 GDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHR 615 Query: 595 ------GPPGPPG 601 GPPGPPG Sbjct: 616 GERGPQGPPGPPG 628 Score = 110 bits (275), Expect = 4e-24 Identities = 71/183 (38%), Positives = 80/183 (43%), Gaps = 37/183 (20%) Query: 460 GPPGPRGFKGD-------MGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 G G +G KG+ M V+GP G GP G G G GP GP G PG+ GP G G Sbjct: 420 GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 479 Query: 513 VGPRGFPGLKGSK-------GSFGTGGP--------------------RGQPGPKGDIGP 545 G G PG G+ G G+ GP RG PGP G G Sbjct: 480 PGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGR 539 Query: 546 PGPEGPPGSPGPSGPQGKPGIAGKTG---SPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 PGP G PGS G G G PG G G PG G G +G PG G G+PG PG G Sbjct: 540 PGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGD 599 Query: 603 QSF 605 + F Sbjct: 600 RGF 602 Score = 101 bits (251), Expect = 2e-21 Identities = 54/120 (45%), Positives = 65/120 (54%), Gaps = 12/120 (10%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G GPPGP G G G+KG G +G KG PG +G +GP G QG+ G+ G G +G G + Sbjct: 1426 GQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAK 1485 Query: 517 GFPGLKGSKGSFGTGGPRGQPGP------KGDIGPPGPEG------PPGSPGPSGPQGKP 564 G G+ G G G GP G PGP KG GP G +G PPGSPGP G +P Sbjct: 1486 GDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQP 1545 Score = 91.3 bits (225), Expect = 2e-18 Identities = 48/97 (49%), Positives = 53/97 (54%), Gaps = 9/97 (9%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPVGERG 511 L G GPPG +G KGD G+ G G G KGD PG GPLGP GP G PG GP G +G Sbjct: 1457 LIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKG 1516 Query: 512 PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548 GP G KG G GP G PGP G++ P P Sbjct: 1517 STGPAG------QKGDSGLPGPPGSPGPPGEVIQPLP 1547 Score = 53.1 bits (126), Expect = 7e-07 Identities = 30/76 (39%), Positives = 34/76 (44%), Gaps = 18/76 (23%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQG------------------P 497 RG PG G G KGD G+ GP G GP G PG GP GP+G P Sbjct: 1473 RGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP 1532 Query: 498 QGQPGEAGPVGERGPV 513 G PG G V + P+ Sbjct: 1533 PGSPGPPGEVIQPLPI 1548 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 155 bits (392), Expect = 1e-37 Identities = 76/146 (52%), Positives = 86/146 (58%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +GAPG PGP G GD G +G G RGP G PG G G GPQG G+ G G+RG G Sbjct: 1082 QGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQ 1141 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 +G G G +G G GP G+ G G GP GP GPPG GPSG +G PG G G PG Sbjct: 1142 KGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGV 1201 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPG 601 RG++G G G G PG PGPPGPPG Sbjct: 1202 RGSVGEAGPEGPPGEPGPPGPPGPPG 1227 Score = 150 bits (380), Expect = 2e-36 Identities = 78/162 (48%), Positives = 90/162 (55%), Gaps = 15/162 (9%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 + G PGP G RG G+ G +G G G +G PG LGP GP GP G+ GE GP G GP G Sbjct: 769 IAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPG 828 Query: 515 PRGFPGLKGSKG---SFGTGGPRG------------QPGPKGDIGPPGPEGPPGSPGPSG 559 RG PG +G G + G GP+G +PG KGD G PGP+G GSPGP G Sbjct: 829 SRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHG 888 Query: 560 PQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 P G PG+ G G+ G GA G G G GPPG G PGP G Sbjct: 889 PNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAG 930 Score = 150 bits (380), Expect = 2e-36 Identities = 78/155 (50%), Positives = 87/155 (56%), Gaps = 9/155 (5%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG GP G +GD G G VG RGP G PG G G G GQPG GP G G G R Sbjct: 933 GEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQR 992 Query: 517 GF---PGLKGSKGSFGTGGPRGQPGP------KGDIGPPGPEGPPGSPGPSGPQGKPGIA 567 G PG +G +G G GP G PG GD GPPGP GPPGS GP G G G A Sbjct: 993 GIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPA 1052 Query: 568 GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G G+PG+ GA+G +G+ G GP GLPG G PG+ Sbjct: 1053 GNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGT 1087 Score = 150 bits (379), Expect = 3e-36 Identities = 80/160 (50%), Positives = 85/160 (53%), Gaps = 12/160 (7%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L G+PGP GP G G G +G G G G PGS G +GP GP G PG AGP+GE G G Sbjct: 880 LAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEG 939 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574 P G G GS G G GP G PG GD G PG +G PG GP GP G G G G PG Sbjct: 940 PPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPG 999 Query: 575 QRGAMGPKGEPGIQGPPGL------------PGPPGPPGS 602 QRG G G PG G PG PGP GPPGS Sbjct: 1000 QRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGS 1039 Score = 150 bits (378), Expect = 4e-36 Identities = 76/147 (51%), Positives = 85/147 (57%), Gaps = 6/147 (4%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GAPG G G G MG GP+G P+G PG G LGPQG GQ G G G+ GP+GP Sbjct: 315 GAPGSKGEAGPTGPMGAMGPLG---PRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPL 371 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G PG S G G G +G+ GP G GP GP+G G GP GP G PG+ G G+ G Sbjct: 372 GIPG---SSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTP 428 Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 GA GP G PG GPPG GPPG PG Q Sbjct: 429 GAKGPTGSPGTSGPPGSAGPPGSPGPQ 455 Score = 149 bits (377), Expect = 6e-36 Identities = 82/160 (51%), Positives = 91/160 (56%), Gaps = 12/160 (7%) Query: 455 LRGAPGPPGPRGFKGDMGVKG---PVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG 511 +RG PG PG GFKG+ G KG P G +GP G PG G GP+G G G GPVGERG Sbjct: 463 IRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERG 522 Query: 512 PVGPRGFP---GLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI-- 566 G RGFP GL G KG+ G GP G GPKG G PG G PG PG G G PG+ Sbjct: 523 APGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQG 582 Query: 567 ----AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G G+PG+ G GP G GI+G PG G PGP GS Sbjct: 583 PEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGS 622 Score = 149 bits (376), Expect = 7e-36 Identities = 77/156 (49%), Positives = 85/156 (54%), Gaps = 9/156 (5%) Query: 456 RGAPGPPGPRGFKGD---MGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 RG GPPG GF G +G GP G GP G G G GP G +G PG G VG+RGP Sbjct: 899 RGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGP 958 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGP------KGDIGPPGPEGPPGSPGPSGPQGKPGI 566 GP G PG KG G G GP G PGP +G +G PG G G PG GP G PG Sbjct: 959 AGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGK 1018 Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G TG+ G +G GP G PG GP G PGP GP G+ Sbjct: 1019 VGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGN 1054 Score = 148 bits (374), Expect = 1e-35 Identities = 77/153 (50%), Positives = 90/153 (58%), Gaps = 6/153 (3%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE---AGPVGERGP 512 +G GP GP G GD G GP+G RGP+G PG G G G G PGE AG G RG Sbjct: 230 QGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGF 289 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGK--- 569 G G PGLKG +G G GP+G+ G G G GP GP G+ GP GP+G PG G+ Sbjct: 290 PGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGP 349 Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G+PGQRGA G G+PG GP G+PG G PG+ Sbjct: 350 QGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGN 382 Score = 147 bits (372), Expect = 2e-35 Identities = 71/150 (47%), Positives = 87/150 (58%), Gaps = 3/150 (2%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G G PG +G G G GP G GP G PG G GPQG +GQPG+ G G +G GP+ Sbjct: 423 GTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPK 482 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGD---IGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 G PG G +G G G G+ GP+GD +GPPGP G G+PG G G G+ G G+ Sbjct: 483 GEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQ 542 Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G+RG +G G G QG PG PG PG PG++ Sbjct: 543 GERGPVGSSGPKGSQGDPGRPGEPGLPGAR 572 Score = 146 bits (369), Expect = 5e-35 Identities = 84/174 (48%), Positives = 95/174 (54%), Gaps = 30/174 (17%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKG------DPGSLGPLGPQGPQGQPG------EA 504 GA GP GPRG G+ G GP G G +G PG +GPLG G G PG EA Sbjct: 330 GAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEA 389 Query: 505 GPVGERGPVGPRG------------FPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP 552 GP G RGP GP+G PGL G+ G+ GT G +G G G GPPG GPP Sbjct: 390 GPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPP 449 Query: 553 GSPGP---SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 GSPGP +GPQG G G G PG +G GPKGEP GP G+ GP GPPG + Sbjct: 450 GSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEP---GPHGIQGPIGPPGEE 500 Score = 145 bits (367), Expect = 8e-35 Identities = 76/167 (45%), Positives = 92/167 (55%), Gaps = 18/167 (10%) Query: 457 GAPGP------PGPRGFKGDMGVKG---PVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV 507 G PGP PG GF G+ G+KG P G RGP+G G G GP GP G PG G + Sbjct: 363 GKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAI 422 Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP------GPSGPQ 561 G G G +G G G+ G G+ GP G PGP+G GP G G PG P G +GP+ Sbjct: 423 GTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPK 482 Query: 562 GKP---GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 G+P GI G G PG+ G GP+G+PG GPPG G G PG++ F Sbjct: 483 GEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGF 529 Score = 145 bits (366), Expect = 1e-34 Identities = 83/181 (45%), Positives = 92/181 (50%), Gaps = 36/181 (19%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGS---------LGPLGPQGPQGQPGEAGPV 507 G PGP GP G KG+ G +G VG G +G+PGS +G GPQGP GQPG G Sbjct: 804 GPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEP 863 Query: 508 GE------------------RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPE 549 GE GP GP G PGLKG +G+ G G G PG G +GPPGP Sbjct: 864 GEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPA 923 Query: 550 GPPGSPGPSGPQGKPGIAGKTGSP------GQRGAMGPKGEPGIQGPP---GLPGPPGPP 600 G PG GP G GK G G G P G RG GP G PG +G P G PGP GPP Sbjct: 924 GAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPP 983 Query: 601 G 601 G Sbjct: 984 G 984 Score = 145 bits (366), Expect = 1e-34 Identities = 77/158 (48%), Positives = 89/158 (56%), Gaps = 15/158 (9%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGG---RGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 RG PGP G G +G G GPVG G +GDPGS GP+GP G G+ G GP G RG Sbjct: 1070 RGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGD 1129 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572 G G G +G KG G G +G PGP G P G +G G PGP GP+G PG G +G Sbjct: 1130 KGDHGDRGDRGQKGHRGFTGLQGLPGPPG---PNGEQGSAGIPGPFGPRGPPGPVGPSGK 1186 Query: 573 PGQRGAMGPKGEPGI---------QGPPGLPGPPGPPG 601 G G +GP G PG+ +GPPG PGPPGPPG Sbjct: 1187 EGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPG 1224 Score = 145 bits (365), Expect = 1e-34 Identities = 83/169 (49%), Positives = 90/169 (53%), Gaps = 24/169 (14%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G G PG RGF G G+ GP G +G +G GS GP G QG G+PGE G G RG G Sbjct: 519 GERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNP 578 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIG---PPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 G G +G G G G G+PGP G IG PG G PG G SG GKPG AG G P Sbjct: 579 GVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVP 638 Query: 574 GQRGA---------MGPKGEPGI------QGPP------GLPGPPGPPG 601 GQRGA GP G PG+ QGPP GLPGPPGPPG Sbjct: 639 GQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPG 687 Score = 143 bits (361), Expect = 4e-34 Identities = 76/153 (49%), Positives = 89/153 (58%), Gaps = 9/153 (5%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP------VGE 509 +G+ GP G RG GD GV G G GPKG+PG G GP GP G+ G+ GP VG Sbjct: 455 QGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGP 514 Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGK 569 GPVG RG PG +G GS G GP+G G +G +G GP+G G PG G G PG G Sbjct: 515 PGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGL 574 Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 TG+P G GP+G+ G G PG G PGPPGS Sbjct: 575 TGNP---GVQGPEGKLGPLGAPGEDGRPGPPGS 604 Score = 143 bits (361), Expect = 4e-34 Identities = 76/155 (49%), Positives = 83/155 (53%), Gaps = 6/155 (3%) Query: 455 LRGAPGP---PGPRGFKGDMGVKGPVGGRG---PKGDPGSLGPLGPQGPQGQPGEAGPVG 508 +RG PG PGP+G GD G G G G +G PG G +GP GP G PG AG G Sbjct: 607 IRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERG 666 Query: 509 ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAG 568 E+GP GP GF GL G G G GG G G GD G GP GP G G G +G+PGI G Sbjct: 667 EQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITG 726 Query: 569 KTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G G G GP G G GP G PG GPPG Q Sbjct: 727 LPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQ 761 Score = 143 bits (361), Expect = 4e-34 Identities = 77/150 (51%), Positives = 81/150 (54%), Gaps = 3/150 (2%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG GP G GD G GPVG G G G GP GP G G PG G VGERG G Sbjct: 1014 GTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDP 1073 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ- 575 G GL GS+G+ GT GP G PG G G PG GP G PG +G +G PG G G G Sbjct: 1074 GPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDH 1133 Query: 576 --RGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 RG G KG G G GLPGPPGP G Q Sbjct: 1134 GDRGDRGQKGHRGFTGLQGLPGPPGPNGEQ 1163 Score = 142 bits (357), Expect = 1e-33 Identities = 73/145 (50%), Positives = 81/145 (55%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG PG RG G+ GV+GP G GP G PG G GP G G G+ G +G GP G Sbjct: 564 GEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSS 623 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G PG G G+ G G RG PG G++GP GP GPPG G G QG PG G G PG Sbjct: 624 GDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPP 683 Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPG 601 G G G+PG QG PG PG GP G Sbjct: 684 GPPGEGGKPGDQGVPGDPGAVGPLG 708 Score = 141 bits (356), Expect = 2e-33 Identities = 74/152 (48%), Positives = 84/152 (55%), Gaps = 12/152 (7%) Query: 456 RGAPGPPGPRGFKGDMGVKGP------VGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509 RG GPPGP GF+G G GP G +G GDPG++GPLGP+G +G P GE Sbjct: 665 RGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNP------GE 718 Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGK 569 RG G G PG KG G G GP+G PGP G G GP G G PG G G PG G Sbjct: 719 RGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGD 778 Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G++GA G G G +G PG GPPGP G Sbjct: 779 RGGIGEKGAEGTAGNDGARGLPGPLGPPGPAG 810 Score = 140 bits (352), Expect = 4e-33 Identities = 77/162 (47%), Positives = 84/162 (51%), Gaps = 15/162 (9%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP------LGPQGPQGQPGEAGPVGE 509 RG PG G G G G KG GG GP G GS GP GP G QG PGE G G Sbjct: 713 RGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGT 772 Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGK 569 GP G RG G KG++G+ G G RG PGP G GP GP G G PGP G G PG G Sbjct: 773 PGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGN 832 Query: 570 TGSPGQR---------GAMGPKGEPGIQGPPGLPGPPGPPGS 602 GS G+ G GP G+PG++G PG PG G GS Sbjct: 833 PGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGS 874 Score = 138 bits (348), Expect = 1e-32 Identities = 74/158 (46%), Positives = 87/158 (55%), Gaps = 12/158 (7%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRG------PKGDPGSLGPLGPQGPQGQPGEAGPVGER 510 GA GP GP+G +G+ G GPVG G G PG+ GP G G G PG AGP G Sbjct: 393 GARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSP 452 Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGP---PGPEGPPGSPGPSGPQGKPGIA 567 GP G G G++G G G G +G+ GPKG+ GP GP GPPG G GP+G PG Sbjct: 453 GPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTV 512 Query: 568 GKTGSPGQRGAMGPKGEP---GIQGPPGLPGPPGPPGS 602 G G G+RGA G +G P G+ GP G G GP GS Sbjct: 513 GPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGS 550 Score = 135 bits (339), Expect = 1e-31 Identities = 76/182 (41%), Positives = 88/182 (48%), Gaps = 33/182 (18%) Query: 453 TILRGAPGPPGP---------RGFKGDMGVKGPVGGRGPKGDPGSL-------------- 489 T +G PGPPGP +G GD G GP+G RG +G+PG Sbjct: 674 TGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGM 733 Query: 490 -------GPLGPQGPQGQPGEAGPVGERGPVGPRGF---PGLKGSKGSFGTGGPRGQPGP 539 GP G GP G PG+ GP G +G G RG PG KG +G G G G G Sbjct: 734 AGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGN 793 Query: 540 KGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGP 599 G G PGP GPPG GP+G +G+PG G G PG RG G +GE G G G GP GP Sbjct: 794 DGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGP 853 Query: 600 PG 601 G Sbjct: 854 DG 855 Score = 134 bits (337), Expect = 2e-31 Identities = 78/160 (48%), Positives = 82/160 (51%), Gaps = 21/160 (13%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGS---LGPLGPQGPQGQPGEAGPVGERGPV 513 G G PG G GD G GP GG G KGDPG GP GP GP G G+ G VG G Sbjct: 942 GLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQR 1001 Query: 514 GPRGFPGLKGSKGSFG-------TG-----GPRGQPGPKGDIGPPGPEGPPGSPGPSGPQ 561 G RG PGL G G+ G TG GP G PG G +G PGPEGP G+ Sbjct: 1002 GERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGN------D 1055 Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G PG G G G RG GP G PG QG PG PGP G PG Sbjct: 1056 GTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPG 1095 Score = 132 bits (332), Expect = 9e-31 Identities = 73/154 (47%), Positives = 85/154 (55%), Gaps = 9/154 (5%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVG---GRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 RG G GP+G +GD G G G RG G+PG GP G GP G PGE G G G Sbjct: 545 RGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGS 604 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPG---PSGPQGKPGIAGK 569 +G RG PG G G G+ G G+PG G+ G PG G PG G PSGP G PG+AG+ Sbjct: 605 IGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGE 664 Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G++G GP G G+ GPPG PG G PG Q Sbjct: 665 R---GEQGPPGPTGFQGLPGPPGPPGEGGKPGDQ 695 Score = 131 bits (330), Expect = 2e-30 Identities = 76/172 (44%), Positives = 86/172 (50%), Gaps = 27/172 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG G G G++G GPVG G G+ G GP GP G QG PG GP GE G G + Sbjct: 636 GVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQ 695 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGD------------IGPPGPEGPPGSPGPSGPQGKP 564 G PG G+ G G G RG PG +G+ G GP+GP GSPGPSG G Sbjct: 696 GVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDT 755 Query: 565 GIAGKTGSPGQR---GAMGPKGE------------PGIQGPPGLPGPPGPPG 601 G G G PG+R G GPKG+ G G GLPGP GPPG Sbjct: 756 GPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPG 807 Score = 128 bits (322), Expect = 1e-29 Identities = 77/175 (44%), Positives = 87/175 (49%), Gaps = 30/175 (17%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLG------PQGPQGQPGEAGPVGER 510 GA G GP+G G GVKG G G KGD GS GP G P GP G PG G G + Sbjct: 843 GAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQ 902 Query: 511 GPVGPRGFPGLKGS------KGSFGTGGPRGQPGPKGD------------IGPPGPEGPP 552 GP G GFPG G G+ G GP G+PG +G +G GP GPP Sbjct: 903 GPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPP 962 Query: 553 GSPGPSGPQGKPGIAGKTGSP------GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G PG G G+ G G G P GQRG +G G+ G +G PGLPGP G PG Sbjct: 963 GGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPG 1017 Score = 127 bits (320), Expect = 2e-29 Identities = 82/195 (42%), Positives = 90/195 (46%), Gaps = 51/195 (26%) Query: 452 VTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQG---QPGEAGPVG 508 VT +RG PGP GP G +G P G RGPKG PG GP G G G QPG GP G Sbjct: 124 VTGIRGRPGPAGPPGSQG------PRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPG 177 Query: 509 ER------------------------------------GPVGPRGFPGLKGSKGSFGTGG 532 GPVGPRG GL+G +G G G Sbjct: 178 HPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTG 237 Query: 533 PRGQ---PGPKGDIGPPGPEGPPGSPGPSGPQGK---PGIAGKTGSPGQRGAMGPKGEPG 586 P G+ PGP G IG GPEGPPG PG G G+ PG G GSPG RG G G PG Sbjct: 238 PPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPG 297 Query: 587 IQGPPGLPGPPGPPG 601 ++G G G GP G Sbjct: 298 LKGHRGHKGLEGPKG 312 Score = 94.4 bits (233), Expect = 3e-19 Identities = 50/104 (48%), Positives = 59/104 (56%), Gaps = 21/104 (20%) Query: 450 RNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509 R T L+G PGPPGP G +G G+ GP G RGP G P GP G+ G GP+ Sbjct: 1145 RGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPG---------PVGPSGKEGNPGPL-- 1193 Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPG 553 GP+GP PG++GS G G GP G+P GPPGP GPPG Sbjct: 1194 -GPIGP---PGVRGSVGEAGPEGPPGEP------GPPGPPGPPG 1227 Score = 79.7 bits (195), Expect = 7e-15 Identities = 48/110 (43%), Positives = 54/110 (49%), Gaps = 21/110 (19%) Query: 497 PQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTG--GPRGQPG----PKGDIGPPGPEG 550 P PGE PV + P G +FG G G +G+PG G G PGP G Sbjct: 85 PVTPPGECCPVCSQTP---------GGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAG 135 Query: 551 PPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPP 600 PPGS GP G + G G PG RG G GEPG+ G PG PGPPG P Sbjct: 136 PPGSQGPRGER------GPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHP 179 Score = 40.0 bits (92), Expect = 0.006 Identities = 19/36 (52%), Positives = 21/36 (58%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPL 492 G GPPG RG G+ G +GP G GP G PG G L Sbjct: 1194 GPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHL 1229 >gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo sapiens] Length = 1424 Score = 154 bits (388), Expect = 3e-37 Identities = 82/160 (51%), Positives = 91/160 (56%), Gaps = 13/160 (8%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP-- 512 LRG PG G G G GVKG G +G G G GP G G PG GP G GP Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDI-------GPPGPEGPPGSPGPSGPQGKPG 565 GP+G PGL+G++G G GP G+ GP+G++ GPPGP GPPG PGP GP G PG Sbjct: 618 YGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPG 677 Query: 566 IAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 GK G P G GP GEPGI G G PGPPGP G Q F Sbjct: 678 SLGKCGDP---GLPGPDGEPGIPG-IGFPGPPGPKGDQGF 713 Score = 150 bits (379), Expect = 3e-36 Identities = 80/161 (49%), Positives = 94/161 (58%), Gaps = 14/161 (8%) Query: 457 GAPGPPGPRGFK--GDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 GAPGPPGP G G G KG +G GPKG PG+ G +GP G G PG G G RG G Sbjct: 1251 GAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPG 1310 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------PGSPGPSGPQGKPG 565 +GFPG+KG KG+ G G G PGP G GPPG G PGSPGP G G+PG Sbjct: 1311 FQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPG 1370 Query: 566 IAGKTGSPGQRGAM---GPKGEPGIQGPPGLPGPPGPPGSQ 603 + G+ G PG G + GP+G+PG G PG PGP G G++ Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNK 1411 Score = 146 bits (369), Expect = 5e-35 Identities = 89/204 (43%), Positives = 98/204 (48%), Gaps = 53/204 (25%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKG---DPGSLGPLGPQGPQGQPGEAGPVGERG 511 L G PGP G GFKG G+ GP G RGP G PGS GP+G +G QG+ G GP GE+G Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170 Query: 512 -------PVGPRG---------------FPGLKGSKGSFGTGGPRGQ------------- 536 P GPRG FPGL G KG+ G GPRG Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230 Query: 537 ----PGPKGDIGPPGPEGPPGSPGPSGP-----------QGKPGIAGKTGSPGQRGAMGP 581 PG G+ GPPG G PG+PGP GP +G G G G PG G MGP Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP 1290 Query: 582 KGEPGIQGPPGLPGPPGPPGSQSF 605 G G G PGLPGP G PG Q F Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGF 1314 Score = 141 bits (355), Expect = 2e-33 Identities = 82/192 (42%), Positives = 99/192 (51%), Gaps = 43/192 (22%) Query: 454 ILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP------- 506 +LR PGP G G +G G +G G G G G++G GP+GP G G GP Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233 Query: 507 ----VGERGPVGPRGFP--------------GLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548 G RGP G RG P G+KG KGS G GP+G PG GD+GPPG Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293 Query: 549 EGPPGSPGPSGP------QGKPGIAGKTGSP------GQRGAMGPKGEPGIQGPPG---- 592 G PG+PG GP QG PG+ G+ G+P G G +GPKG PG++G PG Sbjct: 1294 LGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKI 1353 Query: 593 --LPGPPGPPGS 602 LPG PGPPG+ Sbjct: 1354 ISLPGSPGPPGT 1365 Score = 140 bits (352), Expect = 4e-33 Identities = 80/173 (46%), Positives = 92/173 (53%), Gaps = 32/173 (18%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQ------PGEAGPVG 508 L+G PGP GP G +GD+G G G G +G PGS+G +G G +G+ PG AG G Sbjct: 983 LKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPG 1042 Query: 509 --------------------ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548 GP GP G PGL G G G GQPGP G +GP GP Sbjct: 1043 LPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGL---PGDMGKKGEMGQPGPPGHLGPAGP 1099 Query: 549 EGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 EG PGSPG G GKPG G G G +G +GP PGI+GPPGLPG PG PG Sbjct: 1100 EGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGP---PGIRGPPGLPGFPGSPG 1149 Score = 139 bits (349), Expect = 1e-32 Identities = 78/168 (46%), Positives = 91/168 (54%), Gaps = 24/168 (14%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQP--------------G 502 G PGPPGP+G +G G KG +G G G+PG G G G +G+P G Sbjct: 700 GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759 Query: 503 EAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS--PGPSGP 560 E G GE G +G G PGL G+ G+ G GPRG PG G PPG +GPPG GP G Sbjct: 760 ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPG---PPGEQGPPGRCIEGPRGA 816 Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGI-----QGPPGLPGPPGPPGSQ 603 QG PG+ G G G+RG GPKG+PGI G PG G PG PG Q Sbjct: 817 QGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQ 864 Score = 136 bits (342), Expect = 6e-32 Identities = 69/142 (48%), Positives = 83/142 (58%), Gaps = 12/142 (8%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRG------PKGDPGSLGPLGPQGPQGQPGEAGPVGER 510 G PGP GP G GDMG G +G G P+GDPG G G +G +G PG G +G Sbjct: 1274 GHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPP 1333 Query: 511 GPVGPRGFPGLKGSKGSF------GTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564 GP+GP+G PG++G G+ G+ GP G PG G G PGP GPPG+ GP GP+GKP Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393 Query: 565 GIAGKTGSPGQRGAMGPKGEPG 586 G GK G+PG G G KG G Sbjct: 1394 GKDGKPGTPGPAGEKGNKGSKG 1415 Score = 134 bits (337), Expect = 2e-31 Identities = 75/151 (49%), Positives = 86/151 (56%), Gaps = 6/151 (3%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +GAPG PG +G G GV G G G KG+ G G +G G +GQ G+ GP G RGP Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEY 346 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 KG +G+ G GPRG GP+G GPPG G PGS P G +G PG G GS G+ Sbjct: 347 YDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRP-GLRGAPGWPGLKGSKGE 405 Query: 576 RG-----AMGPKGEPGIQGPPGLPGPPGPPG 601 RG AMG G PG G PGLPG PGPPG Sbjct: 406 RGRPGKDAMGTPGSPGCAGSPGLPGSPGPPG 436 Score = 134 bits (336), Expect = 3e-31 Identities = 68/145 (46%), Positives = 81/145 (55%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG G G G G GP+G RG G+PG LGP G G G G G +G GP G Sbjct: 850 GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNP 909 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G PG +GS G G G RG PG KG+ G G GP G +G+PG+ G G+PG++ Sbjct: 910 GTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEK 969 Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPG 601 G G G PG++G GLPGP GPPG Sbjct: 970 GNRGVPGMPGLKGLKGLPGPAGPPG 994 Score = 132 bits (333), Expect = 7e-31 Identities = 75/171 (43%), Positives = 84/171 (49%), Gaps = 28/171 (16%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PGP G G GDMG KG +G GP PG LGP GP+G G PG G G+ GP G Sbjct: 1065 GPPGPTGDPGLPGDMGKKGEMGQPGP---PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDL 1121 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG-------------------------PEGP 551 GF G+KG G G GP G PG G GP G P GP Sbjct: 1122 GFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGP 1181 Query: 552 PGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G+PG G +G G G G PG++GAMG G G G G PGPPG PG+ Sbjct: 1182 RGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGA 1232 Score = 130 bits (328), Expect = 3e-30 Identities = 77/172 (44%), Positives = 88/172 (51%), Gaps = 23/172 (13%) Query: 457 GAPGPPGPRGF------KGDMGVKGPVGGRGPKGDPGSLGPLGPQGP---QGQPGEAGPV 507 G G PG +GF KG+ GV G G +G KG PG GP GP+G G PGE G Sbjct: 952 GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011 Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQP---------GPKGDIG-----PPGPEGPPG 553 G G +G G PG KG +G+ G G G+P G KG+ G PGP GP G Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071 Query: 554 SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 PG G GK G G+ G PG G GP+G PG G PGLPG PGP G F Sbjct: 1072 DPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123 Score = 130 bits (327), Expect = 3e-30 Identities = 73/159 (45%), Positives = 83/159 (52%), Gaps = 14/159 (8%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L+G+PG PG G G G G G G KG+ G L P+G G PG+ G G+ G G Sbjct: 509 LKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGET--LQPEGQVGVPGDPGLRGQPGRKG 566 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA------- 567 G PG G KG G G G KGD GPPG G PGSPGP+GP G PG Sbjct: 567 LDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626 Query: 568 ----GKTGSPGQRGAMGPKGEPGIQGP-PGLPGPPGPPG 601 G G+PG G GP+GE + P PG PGPPGPPG Sbjct: 627 QGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665 Score = 130 bits (327), Expect = 3e-30 Identities = 80/185 (43%), Positives = 94/185 (50%), Gaps = 39/185 (21%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGR-GPKGDPGSLGPLGPQG---------------PQGQ 500 GAPGPPG G +G++ V PV G GP G PG GP GP G P G+ Sbjct: 634 GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGE 693 Query: 501 PGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG---------PEGP 551 PG G +G GP GP+G G G+KGS G G G+PG G G PG P GP Sbjct: 694 PGIPG-IGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP 752 Query: 552 --PGSPGPSGPQGK------PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP-----G 598 PG PG G G+ PG+ G G+PG G GP+G+PG GPPG GPP G Sbjct: 753 GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812 Query: 599 PPGSQ 603 P G+Q Sbjct: 813 PRGAQ 817 Score = 130 bits (326), Expect = 5e-30 Identities = 74/159 (46%), Positives = 84/159 (52%), Gaps = 14/159 (8%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPG--SLGPLGPQGPQGQPGEAGPVGERGPV 513 RGA G PG G KG G +G G PKGDPG L G G G PG G GE GP+ Sbjct: 814 RGAQGLPGLNGLKGQQGRRGKTG---PKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPL 870 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 G RG+PG G G G G G G G IGPPGP G PG+PG G G PG+ G+ G+P Sbjct: 871 GQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTP 930 Query: 574 GQRGAMGPKGEP---------GIQGPPGLPGPPGPPGSQ 603 G +G G KG P G +G PGL G G PG + Sbjct: 931 GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEK 969 Score = 129 bits (325), Expect = 6e-30 Identities = 83/194 (42%), Positives = 90/194 (46%), Gaps = 49/194 (25%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGP------------QGQPGEA 504 G PG PG G KG+ G G +G G KG G +GP G +GP +G PG Sbjct: 303 GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP 362 Query: 505 GPVGERGPVGPR--------------------GFPGLKGSKGSFGTGG--PRGQPGPKGD 542 GP G RGP GP G+PGLKGSKG G G G PG G Sbjct: 363 GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGC 422 Query: 543 IGPPGPEGPPGSPGP-------SGPQGKPGIAGKTGSPGQRGAMGPKGEPG--------I 587 G PG G PG PGP GP G G+ G GSPG G GPKGEPG I Sbjct: 423 AGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYI 482 Query: 588 QGPPGLPGPPGPPG 601 GPPGLPG PG G Sbjct: 483 PGPPGLPGLPGLHG 496 Score = 125 bits (315), Expect = 9e-29 Identities = 71/159 (44%), Positives = 82/159 (51%), Gaps = 15/159 (9%) Query: 453 TILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 T + G PGPPGP G G G G G G GDPG GP G+PG G +G GP Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGL------PGPDGEPGIPG-IGFPGP 704 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP--------PGSPGPSGPQGKP 564 GP+G G G+KGS G G G+PG G G PG +G PG+PG G +G Sbjct: 705 PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNS 764 Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G G+ G PG G G G G+ GP G PG PGPPG Q Sbjct: 765 GEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQ 803 Score = 125 bits (314), Expect = 1e-28 Identities = 79/179 (44%), Positives = 89/179 (49%), Gaps = 36/179 (20%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG----- 511 G PGPPGPRG +G G GP G G PGS P G +G G PG G GERG Sbjct: 357 GTPGPPGPRGARGPQGPSGPPG---VPGSPGSSRP-GLRGAPGWPGLKGSKGERGRPGKD 412 Query: 512 PVGPRGFPGLKGSKGSFGTGGPRGQPG-------PKGDIGPPGPEGPPGSPGPSGPQGKP 564 +G G PG GS G G+ GP G PG P GD G PG G PG PG GP+G+P Sbjct: 413 AMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEP 472 Query: 565 GIA--------------------GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G+ G G PG++GA G KG PG G GLPG PG PG+Q Sbjct: 473 GLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531 Score = 125 bits (314), Expect = 1e-28 Identities = 72/163 (44%), Positives = 88/163 (53%), Gaps = 15/163 (9%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGP---KGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 +G GP G RG+ G+ G+ GP G G G PG++GP GP G G PG+ G G G Sbjct: 864 QGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGV 923 Query: 513 VGPRGFPGLKGSKGSFGTGGP---------RGQPGPKGDIGPPGPEGP---PGSPGPSGP 560 G RG PG KG +G G GP +G+PG KG G PG +G PG PG G Sbjct: 924 KGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGL 983 Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 +G PG AG G G G+ G GEPG++G PG G G PGS+ Sbjct: 984 KGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026 Score = 122 bits (307), Expect = 7e-28 Identities = 75/171 (43%), Positives = 84/171 (49%), Gaps = 26/171 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGP---VGGRGPKGDPGSLGPLGPQ---GPQGQPGEAGPVGER 510 G PG PG RG G GVKG G +G +GD G+ GP G +G+PG G G Sbjct: 907 GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP 966 Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------------PGSP 555 G G RG PG+ G KG G GP G PGP+GD+G G G PGS Sbjct: 967 GEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026 Query: 556 GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQ-----GPPGLPGPPGPPG 601 G G G PG AG+ G PG G G KGEPG GPPG G PG PG Sbjct: 1027 GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPG 1077 Score = 120 bits (300), Expect = 5e-27 Identities = 70/161 (43%), Positives = 80/161 (49%), Gaps = 17/161 (10%) Query: 463 GPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLK 522 G +G KG+ G GP G G KG G G GPQGP+G PG G G +G G G PG Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 523 GSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGA---- 578 GS G GT G G G G G G +G G PG G G PGI G G GQ+GA Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162 Query: 579 ----MGPKGEP---------GIQGPPGLPGPPGPPGSQSFY 606 + KG+P G+ GPPG PGP GPPG F+ Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFF 203 Score = 119 bits (299), Expect = 6e-27 Identities = 75/174 (43%), Positives = 84/174 (48%), Gaps = 24/174 (13%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEA--GPVGERGPVG 514 G PG PGP+G G G GPVG GP G G G +GP+GP+G GE G GERG G Sbjct: 174 GLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKG 233 Query: 515 PRGFPGLKGS--------------KGSFGTGGPRGQPGPKGDIGPPGP-----EGPPGSP 555 G PG G+ KG G G G+PGP G G PG +G PG P Sbjct: 234 LTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDP 293 Query: 556 GPSGPQGK---PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSFY 606 G G GK PG G G G RG G GE GI+G G GPPG G +Y Sbjct: 294 GLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYY 347 Score = 119 bits (298), Expect = 8e-27 Identities = 74/174 (42%), Positives = 84/174 (48%), Gaps = 28/174 (16%) Query: 457 GAPGPPGPRGF---------KGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV 507 G PGP GP+GF KG G+ G G G G PG+ G GP G G PG +G Sbjct: 70 GLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSK 129 Query: 508 GERG------PVGPRGFPGLKGSKGSFGTGG--------PRGQPGPKGDIGPPGPEGPPG 553 GE+G +G G PG G KG G +G PG G GP G GPPG Sbjct: 130 GEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPG 189 Query: 554 SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGE-----PGIQGPPGLPGPPGPPGS 602 PGP GP G PG G G+ G RG G GE G +G GL GPPGPPG+ Sbjct: 190 FPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGT 243 Score = 119 bits (297), Expect = 1e-26 Identities = 78/176 (44%), Positives = 92/176 (52%), Gaps = 28/176 (15%) Query: 455 LRGAPGPPGP-------RGFKGDMGVKGPVGGRG------PKGDPGSLGPLGPQ--GPQG 499 L G+PGPPGP +G GD G+ G +G G PKG+PG L P GP G Sbjct: 428 LPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPG 487 Query: 500 QPGEAGPVGERGPVGPRGFPGLKGSKGSFG-TG--------GPRGQPGPKGDIG----PP 546 PG G G +G G +G GLKGS GS G TG G +G PG KG+ G P Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPE 547 Query: 547 GPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G G PG PG G G+ G+ G G+PG +G GPKGE + G G GPPG PGS Sbjct: 548 GQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGS 603 Score = 119 bits (297), Expect = 1e-26 Identities = 67/148 (45%), Positives = 80/148 (54%), Gaps = 3/148 (2%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG---PVGERGPV 513 GA GPPGP G G G +G G G KG G+ G G QG +G PG + +G++G Sbjct: 898 GAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP 957 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 G +GF G G KG+ G G G G KG GP GP GP G G +G G+PG+ G GS Sbjct: 958 GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSM 1017 Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G G KG+ G G PG G PG PG Sbjct: 1018 GNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045 Score = 117 bits (294), Expect = 2e-26 Identities = 71/163 (43%), Positives = 81/163 (49%), Gaps = 18/163 (11%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGPVGER 510 G GPPG G G MG G +G GP G+PG+ G G +G +G PG G G++ Sbjct: 880 GILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDK 939 Query: 511 GPVGP---------RGFPGLKGSKGSFGTGGPR---GQPGPKGDIGPPGPEGPPGSPGPS 558 G GP +G PGLKG G+ G G R G PG KG G PGP GPPG G Sbjct: 940 GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999 Query: 559 GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G PG G G PG G MG G G +G G PG G PG Sbjct: 1000 GSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPG 1042 Score = 117 bits (293), Expect = 3e-26 Identities = 75/167 (44%), Positives = 87/167 (52%), Gaps = 32/167 (19%) Query: 444 QHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE 503 +HGEI G PG PG G G+ G+ GP +GDPG GP G QG PG Sbjct: 766 EHGEI--------GLPGLPGLPGTPGNEGLDGP------RGDPGQPGP---PGEQGPPGR 808 Query: 504 AGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPE-----GPPGSPGPS 558 GP G +G PGL G KG G RG+ GPKGD G PG + G GSPG Sbjct: 809 C----IEGPRGAQGLPGLNGLKGQ---QGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIP 861 Query: 559 GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP---GPPGPPGS 602 G QG+ G G+ G PG G +GP GE G+ G G P GPPGPPG+ Sbjct: 862 GHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGN 908 Score = 99.8 bits (247), Expect = 7e-21 Identities = 56/128 (43%), Positives = 71/128 (55%), Gaps = 15/128 (11%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLG------PLGPQGPQGQPGEAGPV--- 507 GAPG PG G +GD G +G G +G KG+PG LG P+GP+GP G G+ G + Sbjct: 1295 GAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKII 1354 Query: 508 ---GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564 G GP G G PG++G G GP G GP G G PG +G PG+PGP+G +G Sbjct: 1355 SLPGSPGPPGTPGEPGMQGEP---GPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNK 1411 Query: 565 GIAGKTGS 572 G G+ S Sbjct: 1412 GSKGEPES 1419 Score = 61.6 bits (148), Expect = 2e-09 Identities = 30/65 (46%), Positives = 38/65 (58%), Gaps = 3/65 (4%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L G+PGPPG G+ G++G G GP G+ G GP G G G+PG GP GE+G G Sbjct: 1356 LPGSPGPPGT---PGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKG 1412 Query: 515 PRGFP 519 +G P Sbjct: 1413 SKGEP 1417 Score = 32.7 bits (73), Expect = 0.99 Identities = 18/50 (36%), Positives = 23/50 (46%), Gaps = 15/50 (30%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVG---------------GRGPKGDPGSL 489 ++G PGPPGP G G G +G G +G KG+P SL Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPESL 1420 >gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo sapiens] Length = 1494 Score = 154 bits (388), Expect = 3e-37 Identities = 82/160 (51%), Positives = 91/160 (56%), Gaps = 13/160 (8%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP-- 512 LRG PG G G G GVKG G +G G G GP G G PG GP G GP Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDI-------GPPGPEGPPGSPGPSGPQGKPG 565 GP+G PGL+G++G G GP G+ GP+G++ GPPGP GPPG PGP GP G PG Sbjct: 618 YGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPG 677 Query: 566 IAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 GK G P G GP GEPGI G G PGPPGP G Q F Sbjct: 678 SLGKCGDP---GLPGPDGEPGIPG-IGFPGPPGPKGDQGF 713 Score = 150 bits (379), Expect = 3e-36 Identities = 80/161 (49%), Positives = 94/161 (58%), Gaps = 14/161 (8%) Query: 457 GAPGPPGPRGFK--GDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 GAPGPPGP G G G KG +G GPKG PG+ G +GP G G PG G G RG G Sbjct: 1251 GAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPG 1310 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------PGSPGPSGPQGKPG 565 +GFPG+KG KG+ G G G PGP G GPPG G PGSPGP G G+PG Sbjct: 1311 FQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPG 1370 Query: 566 IAGKTGSPGQRGAM---GPKGEPGIQGPPGLPGPPGPPGSQ 603 + G+ G PG G + GP+G+PG G PG PGP G G++ Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNK 1411 Score = 149 bits (375), Expect = 9e-36 Identities = 78/160 (48%), Positives = 94/160 (58%), Gaps = 15/160 (9%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRG------PKGDPGSLGPLGPQGPQGQPGEAGPVGER 510 G PGP GP G GDMG G +G G P+GDPG G G +G +G PG G +G Sbjct: 1274 GHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPP 1333 Query: 511 GPVGPRGFPGLKGSKGSF------GTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564 GP+GP+G PG++G G+ G+ GP G PG G G PGP GPPG+ GP GP+GKP Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393 Query: 565 GIAGKTGSP---GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G GK G+P G++G G KGEPG G GLPG G G Sbjct: 1394 GKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433 Score = 146 bits (369), Expect = 5e-35 Identities = 89/204 (43%), Positives = 98/204 (48%), Gaps = 53/204 (25%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKG---DPGSLGPLGPQGPQGQPGEAGPVGERG 511 L G PGP G GFKG G+ GP G RGP G PGS GP+G +G QG+ G GP GE+G Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170 Query: 512 -------PVGPRG---------------FPGLKGSKGSFGTGGPRGQ------------- 536 P GPRG FPGL G KG+ G GPRG Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230 Query: 537 ----PGPKGDIGPPGPEGPPGSPGPSGP-----------QGKPGIAGKTGSPGQRGAMGP 581 PG G+ GPPG G PG+PGP GP +G G G G PG G MGP Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP 1290 Query: 582 KGEPGIQGPPGLPGPPGPPGSQSF 605 G G G PGLPGP G PG Q F Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGF 1314 Score = 141 bits (355), Expect = 2e-33 Identities = 82/192 (42%), Positives = 99/192 (51%), Gaps = 43/192 (22%) Query: 454 ILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP------- 506 +LR PGP G G +G G +G G G G G++G GP+GP G G GP Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233 Query: 507 ----VGERGPVGPRGFP--------------GLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548 G RGP G RG P G+KG KGS G GP+G PG GD+GPPG Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293 Query: 549 EGPPGSPGPSGP------QGKPGIAGKTGSP------GQRGAMGPKGEPGIQGPPG---- 592 G PG+PG GP QG PG+ G+ G+P G G +GPKG PG++G PG Sbjct: 1294 LGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKI 1353 Query: 593 --LPGPPGPPGS 602 LPG PGPPG+ Sbjct: 1354 ISLPGSPGPPGT 1365 Score = 140 bits (352), Expect = 4e-33 Identities = 80/173 (46%), Positives = 92/173 (53%), Gaps = 32/173 (18%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQ------PGEAGPVG 508 L+G PGP GP G +GD+G G G G +G PGS+G +G G +G+ PG AG G Sbjct: 983 LKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPG 1042 Query: 509 --------------------ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548 GP GP G PGL G G G GQPGP G +GP GP Sbjct: 1043 LPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGL---PGDMGKKGEMGQPGPPGHLGPAGP 1099 Query: 549 EGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 EG PGSPG G GKPG G G G +G +GP PGI+GPPGLPG PG PG Sbjct: 1100 EGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGP---PGIRGPPGLPGFPGSPG 1149 Score = 139 bits (349), Expect = 1e-32 Identities = 78/168 (46%), Positives = 91/168 (54%), Gaps = 24/168 (14%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQP--------------G 502 G PGPPGP+G +G G KG +G G G+PG G G G +G+P G Sbjct: 700 GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759 Query: 503 EAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS--PGPSGP 560 E G GE G +G G PGL G+ G+ G GPRG PG G PPG +GPPG GP G Sbjct: 760 ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPG---PPGEQGPPGRCIEGPRGA 816 Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGI-----QGPPGLPGPPGPPGSQ 603 QG PG+ G G G+RG GPKG+PGI G PG G PG PG Q Sbjct: 817 QGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQ 864 Score = 134 bits (337), Expect = 2e-31 Identities = 75/151 (49%), Positives = 86/151 (56%), Gaps = 6/151 (3%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +GAPG PG +G G GV G G G KG+ G G +G G +GQ G+ GP G RGP Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEY 346 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 KG +G+ G GPRG GP+G GPPG G PGS P G +G PG G GS G+ Sbjct: 347 YDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRP-GLRGAPGWPGLKGSKGE 405 Query: 576 RG-----AMGPKGEPGIQGPPGLPGPPGPPG 601 RG AMG G PG G PGLPG PGPPG Sbjct: 406 RGRPGKDAMGTPGSPGCAGSPGLPGSPGPPG 436 Score = 134 bits (336), Expect = 3e-31 Identities = 68/145 (46%), Positives = 81/145 (55%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG G G G G GP+G RG G+PG LGP G G G G G +G GP G Sbjct: 850 GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNP 909 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G PG +GS G G G RG PG KG+ G G GP G +G+PG+ G G+PG++ Sbjct: 910 GTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEK 969 Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPG 601 G G G PG++G GLPGP GPPG Sbjct: 970 GNRGVPGMPGLKGLKGLPGPAGPPG 994 Score = 132 bits (333), Expect = 7e-31 Identities = 75/171 (43%), Positives = 84/171 (49%), Gaps = 28/171 (16%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PGP G G GDMG KG +G GP PG LGP GP+G G PG G G+ GP G Sbjct: 1065 GPPGPTGDPGLPGDMGKKGEMGQPGP---PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDL 1121 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG-------------------------PEGP 551 GF G+KG G G GP G PG G GP G P GP Sbjct: 1122 GFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGP 1181 Query: 552 PGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G+PG G +G G G G PG++GAMG G G G G PGPPG PG+ Sbjct: 1182 RGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGA 1232 Score = 130 bits (328), Expect = 3e-30 Identities = 77/172 (44%), Positives = 88/172 (51%), Gaps = 23/172 (13%) Query: 457 GAPGPPGPRGF------KGDMGVKGPVGGRGPKGDPGSLGPLGPQGP---QGQPGEAGPV 507 G G PG +GF KG+ GV G G +G KG PG GP GP+G G PGE G Sbjct: 952 GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011 Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQP---------GPKGDIG-----PPGPEGPPG 553 G G +G G PG KG +G+ G G G+P G KG+ G PGP GP G Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071 Query: 554 SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 PG G GK G G+ G PG G GP+G PG G PGLPG PGP G F Sbjct: 1072 DPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123 Score = 130 bits (327), Expect = 3e-30 Identities = 73/159 (45%), Positives = 83/159 (52%), Gaps = 14/159 (8%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L+G+PG PG G G G G G G KG+ G L P+G G PG+ G G+ G G Sbjct: 509 LKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGET--LQPEGQVGVPGDPGLRGQPGRKG 566 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA------- 567 G PG G KG G G G KGD GPPG G PGSPGP+GP G PG Sbjct: 567 LDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626 Query: 568 ----GKTGSPGQRGAMGPKGEPGIQGP-PGLPGPPGPPG 601 G G+PG G GP+GE + P PG PGPPGPPG Sbjct: 627 QGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665 Score = 130 bits (327), Expect = 3e-30 Identities = 80/185 (43%), Positives = 94/185 (50%), Gaps = 39/185 (21%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGR-GPKGDPGSLGPLGPQG---------------PQGQ 500 GAPGPPG G +G++ V PV G GP G PG GP GP G P G+ Sbjct: 634 GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGE 693 Query: 501 PGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG---------PEGP 551 PG G +G GP GP+G G G+KGS G G G+PG G G PG P GP Sbjct: 694 PGIPG-IGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP 752 Query: 552 --PGSPGPSGPQGK------PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP-----G 598 PG PG G G+ PG+ G G+PG G GP+G+PG GPPG GPP G Sbjct: 753 GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812 Query: 599 PPGSQ 603 P G+Q Sbjct: 813 PRGAQ 817 Score = 130 bits (326), Expect = 5e-30 Identities = 74/159 (46%), Positives = 84/159 (52%), Gaps = 14/159 (8%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPG--SLGPLGPQGPQGQPGEAGPVGERGPV 513 RGA G PG G KG G +G G PKGDPG L G G G PG G GE GP+ Sbjct: 814 RGAQGLPGLNGLKGQQGRRGKTG---PKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPL 870 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 G RG+PG G G G G G G G IGPPGP G PG+PG G G PG+ G+ G+P Sbjct: 871 GQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTP 930 Query: 574 GQRGAMGPKGEP---------GIQGPPGLPGPPGPPGSQ 603 G +G G KG P G +G PGL G G PG + Sbjct: 931 GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEK 969 Score = 129 bits (325), Expect = 6e-30 Identities = 83/194 (42%), Positives = 90/194 (46%), Gaps = 49/194 (25%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGP------------QGQPGEA 504 G PG PG G KG+ G G +G G KG G +GP G +GP +G PG Sbjct: 303 GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP 362 Query: 505 GPVGERGPVGPR--------------------GFPGLKGSKGSFGTGG--PRGQPGPKGD 542 GP G RGP GP G+PGLKGSKG G G G PG G Sbjct: 363 GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGC 422 Query: 543 IGPPGPEGPPGSPGP-------SGPQGKPGIAGKTGSPGQRGAMGPKGEPG--------I 587 G PG G PG PGP GP G G+ G GSPG G GPKGEPG I Sbjct: 423 AGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYI 482 Query: 588 QGPPGLPGPPGPPG 601 GPPGLPG PG G Sbjct: 483 PGPPGLPGLPGLHG 496 Score = 125 bits (315), Expect = 9e-29 Identities = 71/159 (44%), Positives = 82/159 (51%), Gaps = 15/159 (9%) Query: 453 TILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 T + G PGPPGP G G G G G G GDPG GP G+PG G +G GP Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGL------PGPDGEPGIPG-IGFPGP 704 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP--------PGSPGPSGPQGKP 564 GP+G G G+KGS G G G+PG G G PG +G PG+PG G +G Sbjct: 705 PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNS 764 Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G G+ G PG G G G G+ GP G PG PGPPG Q Sbjct: 765 GEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQ 803 Score = 125 bits (314), Expect = 1e-28 Identities = 79/179 (44%), Positives = 89/179 (49%), Gaps = 36/179 (20%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG----- 511 G PGPPGPRG +G G GP G G PGS P G +G G PG G GERG Sbjct: 357 GTPGPPGPRGARGPQGPSGPPG---VPGSPGSSRP-GLRGAPGWPGLKGSKGERGRPGKD 412 Query: 512 PVGPRGFPGLKGSKGSFGTGGPRGQPG-------PKGDIGPPGPEGPPGSPGPSGPQGKP 564 +G G PG GS G G+ GP G PG P GD G PG G PG PG GP+G+P Sbjct: 413 AMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEP 472 Query: 565 GIA--------------------GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G+ G G PG++GA G KG PG G GLPG PG PG+Q Sbjct: 473 GLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531 Score = 125 bits (314), Expect = 1e-28 Identities = 72/163 (44%), Positives = 88/163 (53%), Gaps = 15/163 (9%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGP---KGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 +G GP G RG+ G+ G+ GP G G G PG++GP GP G G PG+ G G G Sbjct: 864 QGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGV 923 Query: 513 VGPRGFPGLKGSKGSFGTGGP---------RGQPGPKGDIGPPGPEGP---PGSPGPSGP 560 G RG PG KG +G G GP +G+PG KG G PG +G PG PG G Sbjct: 924 KGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGL 983 Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 +G PG AG G G G+ G GEPG++G PG G G PGS+ Sbjct: 984 KGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026 Score = 122 bits (307), Expect = 7e-28 Identities = 75/171 (43%), Positives = 84/171 (49%), Gaps = 26/171 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGP---VGGRGPKGDPGSLGPLGPQ---GPQGQPGEAGPVGER 510 G PG PG RG G GVKG G +G +GD G+ GP G +G+PG G G Sbjct: 907 GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP 966 Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------------PGSP 555 G G RG PG+ G KG G GP G PGP+GD+G G G PGS Sbjct: 967 GEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026 Query: 556 GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQ-----GPPGLPGPPGPPG 601 G G G PG AG+ G PG G G KGEPG GPPG G PG PG Sbjct: 1027 GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPG 1077 Score = 120 bits (300), Expect = 5e-27 Identities = 70/161 (43%), Positives = 80/161 (49%), Gaps = 17/161 (10%) Query: 463 GPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLK 522 G +G KG+ G GP G G KG G G GPQGP+G PG G G +G G G PG Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 523 GSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGA---- 578 GS G GT G G G G G G +G G PG G G PGI G G GQ+GA Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162 Query: 579 ----MGPKGEP---------GIQGPPGLPGPPGPPGSQSFY 606 + KG+P G+ GPPG PGP GPPG F+ Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFF 203 Score = 119 bits (299), Expect = 6e-27 Identities = 75/174 (43%), Positives = 84/174 (48%), Gaps = 24/174 (13%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEA--GPVGERGPVG 514 G PG PGP+G G G GPVG GP G G G +GP+GP+G GE G GERG G Sbjct: 174 GLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKG 233 Query: 515 PRGFPGLKGS--------------KGSFGTGGPRGQPGPKGDIGPPGP-----EGPPGSP 555 G PG G+ KG G G G+PGP G G PG +G PG P Sbjct: 234 LTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDP 293 Query: 556 GPSGPQGK---PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSFY 606 G G GK PG G G G RG G GE GI+G G GPPG G +Y Sbjct: 294 GLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYY 347 Score = 119 bits (298), Expect = 8e-27 Identities = 74/174 (42%), Positives = 84/174 (48%), Gaps = 28/174 (16%) Query: 457 GAPGPPGPRGF---------KGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV 507 G PGP GP+GF KG G+ G G G G PG+ G GP G G PG +G Sbjct: 70 GLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSK 129 Query: 508 GERG------PVGPRGFPGLKGSKGSFGTGG--------PRGQPGPKGDIGPPGPEGPPG 553 GE+G +G G PG G KG G +G PG G GP G GPPG Sbjct: 130 GEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPG 189 Query: 554 SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGE-----PGIQGPPGLPGPPGPPGS 602 PGP GP G PG G G+ G RG G GE G +G GL GPPGPPG+ Sbjct: 190 FPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGT 243 Score = 119 bits (297), Expect = 1e-26 Identities = 78/176 (44%), Positives = 92/176 (52%), Gaps = 28/176 (15%) Query: 455 LRGAPGPPGP-------RGFKGDMGVKGPVGGRG------PKGDPGSLGPLGPQ--GPQG 499 L G+PGPPGP +G GD G+ G +G G PKG+PG L P GP G Sbjct: 428 LPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPG 487 Query: 500 QPGEAGPVGERGPVGPRGFPGLKGSKGSFG-TG--------GPRGQPGPKGDIG----PP 546 PG G G +G G +G GLKGS GS G TG G +G PG KG+ G P Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPE 547 Query: 547 GPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G G PG PG G G+ G+ G G+PG +G GPKGE + G G GPPG PGS Sbjct: 548 GQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGS 603 Score = 119 bits (297), Expect = 1e-26 Identities = 67/148 (45%), Positives = 80/148 (54%), Gaps = 3/148 (2%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG---PVGERGPV 513 GA GPPGP G G G +G G G KG G+ G G QG +G PG + +G++G Sbjct: 898 GAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP 957 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 G +GF G G KG+ G G G G KG GP GP GP G G +G G+PG+ G GS Sbjct: 958 GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSM 1017 Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G G KG+ G G PG G PG PG Sbjct: 1018 GNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045 Score = 117 bits (294), Expect = 2e-26 Identities = 71/163 (43%), Positives = 81/163 (49%), Gaps = 18/163 (11%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGPVGER 510 G GPPG G G MG G +G GP G+PG+ G G +G +G PG G G++ Sbjct: 880 GILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDK 939 Query: 511 GPVGP---------RGFPGLKGSKGSFGTGGPR---GQPGPKGDIGPPGPEGPPGSPGPS 558 G GP +G PGLKG G+ G G R G PG KG G PGP GPPG G Sbjct: 940 GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999 Query: 559 GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G PG G G PG G MG G G +G G PG G PG Sbjct: 1000 GSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPG 1042 Score = 117 bits (293), Expect = 3e-26 Identities = 75/167 (44%), Positives = 87/167 (52%), Gaps = 32/167 (19%) Query: 444 QHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE 503 +HGEI G PG PG G G+ G+ GP +GDPG GP G QG PG Sbjct: 766 EHGEI--------GLPGLPGLPGTPGNEGLDGP------RGDPGQPGP---PGEQGPPGR 808 Query: 504 AGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPE-----GPPGSPGPS 558 GP G +G PGL G KG G RG+ GPKGD G PG + G GSPG Sbjct: 809 C----IEGPRGAQGLPGLNGLKGQ---QGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIP 861 Query: 559 GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP---GPPGPPGS 602 G QG+ G G+ G PG G +GP GE G+ G G P GPPGPPG+ Sbjct: 862 GHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGN 908 Score = 104 bits (259), Expect = 3e-22 Identities = 63/153 (41%), Positives = 74/153 (48%), Gaps = 36/153 (23%) Query: 457 GAPGPPGPRG------------------FKGDMGVKGPVGGRGP---KGDPGSLGPL--- 492 G PG PGPRG F G +G GP+G +GP +GDPG+L + Sbjct: 1298 GTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLP 1357 Query: 493 GPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP 552 G GP G PGE G GE GP GP G+ G GPRG+PG G PG GP Sbjct: 1358 GSPGPPGTPGEPGMQGEPGPPGP---------PGNLGPCGPRGKPGKD---GKPGTPGPA 1405 Query: 553 GSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEP 585 G G G +G+PG AG G PG +G G G P Sbjct: 1406 GEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438 Score = 75.5 bits (184), Expect = 1e-13 Identities = 41/92 (44%), Positives = 48/92 (52%), Gaps = 9/92 (9%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L G+PGPPG G G G GP PG G LGP GP+G+PG+ G G GP G Sbjct: 1356 LPGSPGPPGTPGEPGMQGEPGP---------PGPPGNLGPCGPRGKPGKDGKPGTPGPAG 1406 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPP 546 +G G KG G G+ G G G +GD G P Sbjct: 1407 EKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438 Score = 49.3 bits (116), Expect = 1e-05 Identities = 31/93 (33%), Positives = 39/93 (41%), Gaps = 12/93 (12%) Query: 455 LRGAPGPPGPRGFKGDMGVKG------------PVGGRGPKGDPGSLGPLGPQGPQGQPG 502 ++G PGPPGP G G G +G P G +G KG G GP G G G G Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKG 1430 Query: 503 EAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRG 535 + G G RGF + S+ + P G Sbjct: 1431 KRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEG 1463 >gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo sapiens] Length = 1637 Score = 154 bits (388), Expect = 3e-37 Identities = 82/160 (51%), Positives = 91/160 (56%), Gaps = 13/160 (8%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP-- 512 LRG PG G G G GVKG G +G G G GP G G PG GP G GP Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDI-------GPPGPEGPPGSPGPSGPQGKPG 565 GP+G PGL+G++G G GP G+ GP+G++ GPPGP GPPG PGP GP G PG Sbjct: 618 YGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPG 677 Query: 566 IAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 GK G P G GP GEPGI G G PGPPGP G Q F Sbjct: 678 SLGKCGDP---GLPGPDGEPGIPG-IGFPGPPGPKGDQGF 713 Score = 150 bits (379), Expect = 3e-36 Identities = 80/161 (49%), Positives = 94/161 (58%), Gaps = 14/161 (8%) Query: 457 GAPGPPGPRGFK--GDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 GAPGPPGP G G G KG +G GPKG PG+ G +GP G G PG G G RG G Sbjct: 1251 GAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPG 1310 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------PGSPGPSGPQGKPG 565 +GFPG+KG KG+ G G G PGP G GPPG G PGSPGP G G+PG Sbjct: 1311 FQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPG 1370 Query: 566 IAGKTGSPGQRGAM---GPKGEPGIQGPPGLPGPPGPPGSQ 603 + G+ G PG G + GP+G+PG G PG PGP G G++ Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNK 1411 Score = 149 bits (375), Expect = 9e-36 Identities = 78/160 (48%), Positives = 94/160 (58%), Gaps = 15/160 (9%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRG------PKGDPGSLGPLGPQGPQGQPGEAGPVGER 510 G PGP GP G GDMG G +G G P+GDPG G G +G +G PG G +G Sbjct: 1274 GHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPP 1333 Query: 511 GPVGPRGFPGLKGSKGSF------GTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564 GP+GP+G PG++G G+ G+ GP G PG G G PGP GPPG+ GP GP+GKP Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393 Query: 565 GIAGKTGSP---GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G GK G+P G++G G KGEPG G GLPG G G Sbjct: 1394 GKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433 Score = 146 bits (369), Expect = 5e-35 Identities = 89/204 (43%), Positives = 98/204 (48%), Gaps = 53/204 (25%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKG---DPGSLGPLGPQGPQGQPGEAGPVGERG 511 L G PGP G GFKG G+ GP G RGP G PGS GP+G +G QG+ G GP GE+G Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170 Query: 512 -------PVGPRG---------------FPGLKGSKGSFGTGGPRGQ------------- 536 P GPRG FPGL G KG+ G GPRG Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230 Query: 537 ----PGPKGDIGPPGPEGPPGSPGPSGP-----------QGKPGIAGKTGSPGQRGAMGP 581 PG G+ GPPG G PG+PGP GP +G G G G PG G MGP Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP 1290 Query: 582 KGEPGIQGPPGLPGPPGPPGSQSF 605 G G G PGLPGP G PG Q F Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGF 1314 Score = 141 bits (355), Expect = 2e-33 Identities = 82/192 (42%), Positives = 99/192 (51%), Gaps = 43/192 (22%) Query: 454 ILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP------- 506 +LR PGP G G +G G +G G G G G++G GP+GP G G GP Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233 Query: 507 ----VGERGPVGPRGFP--------------GLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548 G RGP G RG P G+KG KGS G GP+G PG GD+GPPG Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293 Query: 549 EGPPGSPGPSGP------QGKPGIAGKTGSP------GQRGAMGPKGEPGIQGPPG---- 592 G PG+PG GP QG PG+ G+ G+P G G +GPKG PG++G PG Sbjct: 1294 LGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKI 1353 Query: 593 --LPGPPGPPGS 602 LPG PGPPG+ Sbjct: 1354 ISLPGSPGPPGT 1365 Score = 140 bits (352), Expect = 4e-33 Identities = 80/173 (46%), Positives = 92/173 (53%), Gaps = 32/173 (18%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQ------PGEAGPVG 508 L+G PGP GP G +GD+G G G G +G PGS+G +G G +G+ PG AG G Sbjct: 983 LKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPG 1042 Query: 509 --------------------ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548 GP GP G PGL G G G GQPGP G +GP GP Sbjct: 1043 LPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGL---PGDMGKKGEMGQPGPPGHLGPAGP 1099 Query: 549 EGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 EG PGSPG G GKPG G G G +G +GP PGI+GPPGLPG PG PG Sbjct: 1100 EGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGP---PGIRGPPGLPGFPGSPG 1149 Score = 139 bits (349), Expect = 1e-32 Identities = 78/168 (46%), Positives = 91/168 (54%), Gaps = 24/168 (14%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQP--------------G 502 G PGPPGP+G +G G KG +G G G+PG G G G +G+P G Sbjct: 700 GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759 Query: 503 EAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS--PGPSGP 560 E G GE G +G G PGL G+ G+ G GPRG PG G PPG +GPPG GP G Sbjct: 760 ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPG---PPGEQGPPGRCIEGPRGA 816 Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGI-----QGPPGLPGPPGPPGSQ 603 QG PG+ G G G+RG GPKG+PGI G PG G PG PG Q Sbjct: 817 QGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQ 864 Score = 134 bits (337), Expect = 2e-31 Identities = 75/151 (49%), Positives = 86/151 (56%), Gaps = 6/151 (3%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +GAPG PG +G G GV G G G KG+ G G +G G +GQ G+ GP G RGP Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEY 346 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 KG +G+ G GPRG GP+G GPPG G PGS P G +G PG G GS G+ Sbjct: 347 YDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRP-GLRGAPGWPGLKGSKGE 405 Query: 576 RG-----AMGPKGEPGIQGPPGLPGPPGPPG 601 RG AMG G PG G PGLPG PGPPG Sbjct: 406 RGRPGKDAMGTPGSPGCAGSPGLPGSPGPPG 436 Score = 134 bits (336), Expect = 3e-31 Identities = 68/145 (46%), Positives = 81/145 (55%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG G G G G GP+G RG G+PG LGP G G G G G +G GP G Sbjct: 850 GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNP 909 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G PG +GS G G G RG PG KG+ G G GP G +G+PG+ G G+PG++ Sbjct: 910 GTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEK 969 Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPG 601 G G G PG++G GLPGP GPPG Sbjct: 970 GNRGVPGMPGLKGLKGLPGPAGPPG 994 Score = 132 bits (333), Expect = 7e-31 Identities = 75/171 (43%), Positives = 84/171 (49%), Gaps = 28/171 (16%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PGP G G GDMG KG +G GP PG LGP GP+G G PG G G+ GP G Sbjct: 1065 GPPGPTGDPGLPGDMGKKGEMGQPGP---PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDL 1121 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG-------------------------PEGP 551 GF G+KG G G GP G PG G GP G P GP Sbjct: 1122 GFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGP 1181 Query: 552 PGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G+PG G +G G G G PG++GAMG G G G G PGPPG PG+ Sbjct: 1182 RGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGA 1232 Score = 130 bits (328), Expect = 3e-30 Identities = 77/172 (44%), Positives = 88/172 (51%), Gaps = 23/172 (13%) Query: 457 GAPGPPGPRGF------KGDMGVKGPVGGRGPKGDPGSLGPLGPQGP---QGQPGEAGPV 507 G G PG +GF KG+ GV G G +G KG PG GP GP+G G PGE G Sbjct: 952 GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011 Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQP---------GPKGDIG-----PPGPEGPPG 553 G G +G G PG KG +G+ G G G+P G KG+ G PGP GP G Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071 Query: 554 SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 PG G GK G G+ G PG G GP+G PG G PGLPG PGP G F Sbjct: 1072 DPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123 Score = 130 bits (327), Expect = 3e-30 Identities = 73/159 (45%), Positives = 83/159 (52%), Gaps = 14/159 (8%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L+G+PG PG G G G G G G KG+ G L P+G G PG+ G G+ G G Sbjct: 509 LKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGET--LQPEGQVGVPGDPGLRGQPGRKG 566 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA------- 567 G PG G KG G G G KGD GPPG G PGSPGP+GP G PG Sbjct: 567 LDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626 Query: 568 ----GKTGSPGQRGAMGPKGEPGIQGP-PGLPGPPGPPG 601 G G+PG G GP+GE + P PG PGPPGPPG Sbjct: 627 QGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665 Score = 130 bits (327), Expect = 3e-30 Identities = 80/185 (43%), Positives = 94/185 (50%), Gaps = 39/185 (21%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGR-GPKGDPGSLGPLGPQG---------------PQGQ 500 GAPGPPG G +G++ V PV G GP G PG GP GP G P G+ Sbjct: 634 GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGE 693 Query: 501 PGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG---------PEGP 551 PG G +G GP GP+G G G+KGS G G G+PG G G PG P GP Sbjct: 694 PGIPG-IGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP 752 Query: 552 --PGSPGPSGPQGK------PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP-----G 598 PG PG G G+ PG+ G G+PG G GP+G+PG GPPG GPP G Sbjct: 753 GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812 Query: 599 PPGSQ 603 P G+Q Sbjct: 813 PRGAQ 817 Score = 130 bits (326), Expect = 5e-30 Identities = 74/159 (46%), Positives = 84/159 (52%), Gaps = 14/159 (8%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPG--SLGPLGPQGPQGQPGEAGPVGERGPV 513 RGA G PG G KG G +G G PKGDPG L G G G PG G GE GP+ Sbjct: 814 RGAQGLPGLNGLKGQQGRRGKTG---PKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPL 870 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 G RG+PG G G G G G G G IGPPGP G PG+PG G G PG+ G+ G+P Sbjct: 871 GQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTP 930 Query: 574 GQRGAMGPKGEP---------GIQGPPGLPGPPGPPGSQ 603 G +G G KG P G +G PGL G G PG + Sbjct: 931 GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEK 969 Score = 129 bits (325), Expect = 6e-30 Identities = 83/194 (42%), Positives = 90/194 (46%), Gaps = 49/194 (25%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGP------------QGQPGEA 504 G PG PG G KG+ G G +G G KG G +GP G +GP +G PG Sbjct: 303 GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP 362 Query: 505 GPVGERGPVGPR--------------------GFPGLKGSKGSFGTGG--PRGQPGPKGD 542 GP G RGP GP G+PGLKGSKG G G G PG G Sbjct: 363 GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGC 422 Query: 543 IGPPGPEGPPGSPGP-------SGPQGKPGIAGKTGSPGQRGAMGPKGEPG--------I 587 G PG G PG PGP GP G G+ G GSPG G GPKGEPG I Sbjct: 423 AGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYI 482 Query: 588 QGPPGLPGPPGPPG 601 GPPGLPG PG G Sbjct: 483 PGPPGLPGLPGLHG 496 Score = 125 bits (315), Expect = 9e-29 Identities = 71/159 (44%), Positives = 82/159 (51%), Gaps = 15/159 (9%) Query: 453 TILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 T + G PGPPGP G G G G G G GDPG GP G+PG G +G GP Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGL------PGPDGEPGIPG-IGFPGP 704 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP--------PGSPGPSGPQGKP 564 GP+G G G+KGS G G G+PG G G PG +G PG+PG G +G Sbjct: 705 PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNS 764 Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G G+ G PG G G G G+ GP G PG PGPPG Q Sbjct: 765 GEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQ 803 Score = 125 bits (314), Expect = 1e-28 Identities = 79/179 (44%), Positives = 89/179 (49%), Gaps = 36/179 (20%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG----- 511 G PGPPGPRG +G G GP G G PGS P G +G G PG G GERG Sbjct: 357 GTPGPPGPRGARGPQGPSGPPG---VPGSPGSSRP-GLRGAPGWPGLKGSKGERGRPGKD 412 Query: 512 PVGPRGFPGLKGSKGSFGTGGPRGQPG-------PKGDIGPPGPEGPPGSPGPSGPQGKP 564 +G G PG GS G G+ GP G PG P GD G PG G PG PG GP+G+P Sbjct: 413 AMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEP 472 Query: 565 GIA--------------------GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G+ G G PG++GA G KG PG G GLPG PG PG+Q Sbjct: 473 GLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531 Score = 125 bits (314), Expect = 1e-28 Identities = 72/163 (44%), Positives = 88/163 (53%), Gaps = 15/163 (9%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGP---KGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 +G GP G RG+ G+ G+ GP G G G PG++GP GP G G PG+ G G G Sbjct: 864 QGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGV 923 Query: 513 VGPRGFPGLKGSKGSFGTGGP---------RGQPGPKGDIGPPGPEGP---PGSPGPSGP 560 G RG PG KG +G G GP +G+PG KG G PG +G PG PG G Sbjct: 924 KGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGL 983 Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 +G PG AG G G G+ G GEPG++G PG G G PGS+ Sbjct: 984 KGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026 Score = 122 bits (307), Expect = 7e-28 Identities = 75/171 (43%), Positives = 84/171 (49%), Gaps = 26/171 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGP---VGGRGPKGDPGSLGPLGPQ---GPQGQPGEAGPVGER 510 G PG PG RG G GVKG G +G +GD G+ GP G +G+PG G G Sbjct: 907 GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP 966 Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------------PGSP 555 G G RG PG+ G KG G GP G PGP+GD+G G G PGS Sbjct: 967 GEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026 Query: 556 GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQ-----GPPGLPGPPGPPG 601 G G G PG AG+ G PG G G KGEPG GPPG G PG PG Sbjct: 1027 GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPG 1077 Score = 120 bits (300), Expect = 5e-27 Identities = 70/161 (43%), Positives = 80/161 (49%), Gaps = 17/161 (10%) Query: 463 GPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLK 522 G +G KG+ G GP G G KG G G GPQGP+G PG G G +G G G PG Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 523 GSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGA---- 578 GS G GT G G G G G G +G G PG G G PGI G G GQ+GA Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162 Query: 579 ----MGPKGEP---------GIQGPPGLPGPPGPPGSQSFY 606 + KG+P G+ GPPG PGP GPPG F+ Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFF 203 Score = 119 bits (299), Expect = 6e-27 Identities = 75/174 (43%), Positives = 84/174 (48%), Gaps = 24/174 (13%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEA--GPVGERGPVG 514 G PG PGP+G G G GPVG GP G G G +GP+GP+G GE G GERG G Sbjct: 174 GLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKG 233 Query: 515 PRGFPGLKGS--------------KGSFGTGGPRGQPGPKGDIGPPGP-----EGPPGSP 555 G PG G+ KG G G G+PGP G G PG +G PG P Sbjct: 234 LTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDP 293 Query: 556 GPSGPQGK---PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSFY 606 G G GK PG G G G RG G GE GI+G G GPPG G +Y Sbjct: 294 GLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYY 347 Score = 119 bits (298), Expect = 8e-27 Identities = 74/174 (42%), Positives = 84/174 (48%), Gaps = 28/174 (16%) Query: 457 GAPGPPGPRGF---------KGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV 507 G PGP GP+GF KG G+ G G G G PG+ G GP G G PG +G Sbjct: 70 GLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSK 129 Query: 508 GERG------PVGPRGFPGLKGSKGSFGTGG--------PRGQPGPKGDIGPPGPEGPPG 553 GE+G +G G PG G KG G +G PG G GP G GPPG Sbjct: 130 GEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPG 189 Query: 554 SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGE-----PGIQGPPGLPGPPGPPGS 602 PGP GP G PG G G+ G RG G GE G +G GL GPPGPPG+ Sbjct: 190 FPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGT 243 Score = 119 bits (297), Expect = 1e-26 Identities = 78/176 (44%), Positives = 92/176 (52%), Gaps = 28/176 (15%) Query: 455 LRGAPGPPGP-------RGFKGDMGVKGPVGGRG------PKGDPGSLGPLGPQ--GPQG 499 L G+PGPPGP +G GD G+ G +G G PKG+PG L P GP G Sbjct: 428 LPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPG 487 Query: 500 QPGEAGPVGERGPVGPRGFPGLKGSKGSFG-TG--------GPRGQPGPKGDIG----PP 546 PG G G +G G +G GLKGS GS G TG G +G PG KG+ G P Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPE 547 Query: 547 GPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G G PG PG G G+ G+ G G+PG +G GPKGE + G G GPPG PGS Sbjct: 548 GQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGS 603 Score = 119 bits (297), Expect = 1e-26 Identities = 67/148 (45%), Positives = 80/148 (54%), Gaps = 3/148 (2%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG---PVGERGPV 513 GA GPPGP G G G +G G G KG G+ G G QG +G PG + +G++G Sbjct: 898 GAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP 957 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 G +GF G G KG+ G G G G KG GP GP GP G G +G G+PG+ G GS Sbjct: 958 GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSM 1017 Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G G KG+ G G PG G PG PG Sbjct: 1018 GNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045 Score = 117 bits (294), Expect = 2e-26 Identities = 71/163 (43%), Positives = 81/163 (49%), Gaps = 18/163 (11%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGPVGER 510 G GPPG G G MG G +G GP G+PG+ G G +G +G PG G G++ Sbjct: 880 GILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDK 939 Query: 511 GPVGP---------RGFPGLKGSKGSFGTGGPR---GQPGPKGDIGPPGPEGPPGSPGPS 558 G GP +G PGLKG G+ G G R G PG KG G PGP GPPG G Sbjct: 940 GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999 Query: 559 GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G PG G G PG G MG G G +G G PG G PG Sbjct: 1000 GSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPG 1042 Score = 117 bits (293), Expect = 3e-26 Identities = 75/167 (44%), Positives = 87/167 (52%), Gaps = 32/167 (19%) Query: 444 QHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE 503 +HGEI G PG PG G G+ G+ GP +GDPG GP G QG PG Sbjct: 766 EHGEI--------GLPGLPGLPGTPGNEGLDGP------RGDPGQPGP---PGEQGPPGR 808 Query: 504 AGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPE-----GPPGSPGPS 558 GP G +G PGL G KG G RG+ GPKGD G PG + G GSPG Sbjct: 809 C----IEGPRGAQGLPGLNGLKGQ---QGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIP 861 Query: 559 GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP---GPPGPPGS 602 G QG+ G G+ G PG G +GP GE G+ G G P GPPGPPG+ Sbjct: 862 GHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGN 908 Score = 104 bits (259), Expect = 3e-22 Identities = 63/153 (41%), Positives = 74/153 (48%), Gaps = 36/153 (23%) Query: 457 GAPGPPGPRG------------------FKGDMGVKGPVGGRGP---KGDPGSLGPL--- 492 G PG PGPRG F G +G GP+G +GP +GDPG+L + Sbjct: 1298 GTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLP 1357 Query: 493 GPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP 552 G GP G PGE G GE GP GP G+ G GPRG+PG G PG GP Sbjct: 1358 GSPGPPGTPGEPGMQGEPGPPGP---------PGNLGPCGPRGKPGKD---GKPGTPGPA 1405 Query: 553 GSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEP 585 G G G +G+PG AG G PG +G G G P Sbjct: 1406 GEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438 Score = 75.5 bits (184), Expect = 1e-13 Identities = 41/92 (44%), Positives = 48/92 (52%), Gaps = 9/92 (9%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L G+PGPPG G G G GP PG G LGP GP+G+PG+ G G GP G Sbjct: 1356 LPGSPGPPGTPGEPGMQGEPGP---------PGPPGNLGPCGPRGKPGKDGKPGTPGPAG 1406 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPP 546 +G G KG G G+ G G G +GD G P Sbjct: 1407 EKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438 Score = 49.3 bits (116), Expect = 1e-05 Identities = 31/93 (33%), Positives = 39/93 (41%), Gaps = 12/93 (12%) Query: 455 LRGAPGPPGPRGFKGDMGVKG------------PVGGRGPKGDPGSLGPLGPQGPQGQPG 502 ++G PGPPGP G G G +G P G +G KG G GP G G G G Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKG 1430 Query: 503 EAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRG 535 + G G RGF + S+ + P G Sbjct: 1431 KRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEG 1463 >gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo sapiens] Length = 1670 Score = 154 bits (388), Expect = 3e-37 Identities = 82/160 (51%), Positives = 91/160 (56%), Gaps = 13/160 (8%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP-- 512 LRG PG G G G GVKG G +G G G GP G G PG GP G GP Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDI-------GPPGPEGPPGSPGPSGPQGKPG 565 GP+G PGL+G++G G GP G+ GP+G++ GPPGP GPPG PGP GP G PG Sbjct: 618 YGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPG 677 Query: 566 IAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 GK G P G GP GEPGI G G PGPPGP G Q F Sbjct: 678 SLGKCGDP---GLPGPDGEPGIPG-IGFPGPPGPKGDQGF 713 Score = 150 bits (379), Expect = 3e-36 Identities = 80/161 (49%), Positives = 94/161 (58%), Gaps = 14/161 (8%) Query: 457 GAPGPPGPRGFK--GDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 GAPGPPGP G G G KG +G GPKG PG+ G +GP G G PG G G RG G Sbjct: 1251 GAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPG 1310 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------PGSPGPSGPQGKPG 565 +GFPG+KG KG+ G G G PGP G GPPG G PGSPGP G G+PG Sbjct: 1311 FQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPG 1370 Query: 566 IAGKTGSPGQRGAM---GPKGEPGIQGPPGLPGPPGPPGSQ 603 + G+ G PG G + GP+G+PG G PG PGP G G++ Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNK 1411 Score = 149 bits (375), Expect = 9e-36 Identities = 78/160 (48%), Positives = 94/160 (58%), Gaps = 15/160 (9%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRG------PKGDPGSLGPLGPQGPQGQPGEAGPVGER 510 G PGP GP G GDMG G +G G P+GDPG G G +G +G PG G +G Sbjct: 1274 GHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPP 1333 Query: 511 GPVGPRGFPGLKGSKGSF------GTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564 GP+GP+G PG++G G+ G+ GP G PG G G PGP GPPG+ GP GP+GKP Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393 Query: 565 GIAGKTGSP---GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G GK G+P G++G G KGEPG G GLPG G G Sbjct: 1394 GKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433 Score = 146 bits (369), Expect = 5e-35 Identities = 89/204 (43%), Positives = 98/204 (48%), Gaps = 53/204 (25%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKG---DPGSLGPLGPQGPQGQPGEAGPVGERG 511 L G PGP G GFKG G+ GP G RGP G PGS GP+G +G QG+ G GP GE+G Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170 Query: 512 -------PVGPRG---------------FPGLKGSKGSFGTGGPRGQ------------- 536 P GPRG FPGL G KG+ G GPRG Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230 Query: 537 ----PGPKGDIGPPGPEGPPGSPGPSGP-----------QGKPGIAGKTGSPGQRGAMGP 581 PG G+ GPPG G PG+PGP GP +G G G G PG G MGP Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP 1290 Query: 582 KGEPGIQGPPGLPGPPGPPGSQSF 605 G G G PGLPGP G PG Q F Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGF 1314 Score = 141 bits (355), Expect = 2e-33 Identities = 82/192 (42%), Positives = 99/192 (51%), Gaps = 43/192 (22%) Query: 454 ILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP------- 506 +LR PGP G G +G G +G G G G G++G GP+GP G G GP Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233 Query: 507 ----VGERGPVGPRGFP--------------GLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548 G RGP G RG P G+KG KGS G GP+G PG GD+GPPG Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293 Query: 549 EGPPGSPGPSGP------QGKPGIAGKTGSP------GQRGAMGPKGEPGIQGPPG---- 592 G PG+PG GP QG PG+ G+ G+P G G +GPKG PG++G PG Sbjct: 1294 LGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKI 1353 Query: 593 --LPGPPGPPGS 602 LPG PGPPG+ Sbjct: 1354 ISLPGSPGPPGT 1365 Score = 140 bits (352), Expect = 4e-33 Identities = 80/173 (46%), Positives = 92/173 (53%), Gaps = 32/173 (18%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQ------PGEAGPVG 508 L+G PGP GP G +GD+G G G G +G PGS+G +G G +G+ PG AG G Sbjct: 983 LKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPG 1042 Query: 509 --------------------ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548 GP GP G PGL G G G GQPGP G +GP GP Sbjct: 1043 LPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGL---PGDMGKKGEMGQPGPPGHLGPAGP 1099 Query: 549 EGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 EG PGSPG G GKPG G G G +G +GP PGI+GPPGLPG PG PG Sbjct: 1100 EGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGP---PGIRGPPGLPGFPGSPG 1149 Score = 139 bits (349), Expect = 1e-32 Identities = 78/168 (46%), Positives = 91/168 (54%), Gaps = 24/168 (14%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQP--------------G 502 G PGPPGP+G +G G KG +G G G+PG G G G +G+P G Sbjct: 700 GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759 Query: 503 EAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS--PGPSGP 560 E G GE G +G G PGL G+ G+ G GPRG PG G PPG +GPPG GP G Sbjct: 760 ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPG---PPGEQGPPGRCIEGPRGA 816 Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGI-----QGPPGLPGPPGPPGSQ 603 QG PG+ G G G+RG GPKG+PGI G PG G PG PG Q Sbjct: 817 QGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQ 864 Score = 134 bits (337), Expect = 2e-31 Identities = 75/151 (49%), Positives = 86/151 (56%), Gaps = 6/151 (3%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +GAPG PG +G G GV G G G KG+ G G +G G +GQ G+ GP G RGP Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEY 346 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 KG +G+ G GPRG GP+G GPPG G PGS P G +G PG G GS G+ Sbjct: 347 YDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRP-GLRGAPGWPGLKGSKGE 405 Query: 576 RG-----AMGPKGEPGIQGPPGLPGPPGPPG 601 RG AMG G PG G PGLPG PGPPG Sbjct: 406 RGRPGKDAMGTPGSPGCAGSPGLPGSPGPPG 436 Score = 134 bits (336), Expect = 3e-31 Identities = 68/145 (46%), Positives = 81/145 (55%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG G G G G GP+G RG G+PG LGP G G G G G +G GP G Sbjct: 850 GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNP 909 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G PG +GS G G G RG PG KG+ G G GP G +G+PG+ G G+PG++ Sbjct: 910 GTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEK 969 Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPG 601 G G G PG++G GLPGP GPPG Sbjct: 970 GNRGVPGMPGLKGLKGLPGPAGPPG 994 Score = 132 bits (333), Expect = 7e-31 Identities = 75/171 (43%), Positives = 84/171 (49%), Gaps = 28/171 (16%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PGP G G GDMG KG +G GP PG LGP GP+G G PG G G+ GP G Sbjct: 1065 GPPGPTGDPGLPGDMGKKGEMGQPGP---PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDL 1121 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG-------------------------PEGP 551 GF G+KG G G GP G PG G GP G P GP Sbjct: 1122 GFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGP 1181 Query: 552 PGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G+PG G +G G G G PG++GAMG G G G G PGPPG PG+ Sbjct: 1182 RGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGA 1232 Score = 130 bits (328), Expect = 3e-30 Identities = 77/172 (44%), Positives = 88/172 (51%), Gaps = 23/172 (13%) Query: 457 GAPGPPGPRGF------KGDMGVKGPVGGRGPKGDPGSLGPLGPQGP---QGQPGEAGPV 507 G G PG +GF KG+ GV G G +G KG PG GP GP+G G PGE G Sbjct: 952 GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011 Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQP---------GPKGDIG-----PPGPEGPPG 553 G G +G G PG KG +G+ G G G+P G KG+ G PGP GP G Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071 Query: 554 SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 PG G GK G G+ G PG G GP+G PG G PGLPG PGP G F Sbjct: 1072 DPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123 Score = 130 bits (327), Expect = 3e-30 Identities = 73/159 (45%), Positives = 83/159 (52%), Gaps = 14/159 (8%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L+G+PG PG G G G G G G KG+ G L P+G G PG+ G G+ G G Sbjct: 509 LKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGET--LQPEGQVGVPGDPGLRGQPGRKG 566 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA------- 567 G PG G KG G G G KGD GPPG G PGSPGP+GP G PG Sbjct: 567 LDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626 Query: 568 ----GKTGSPGQRGAMGPKGEPGIQGP-PGLPGPPGPPG 601 G G+PG G GP+GE + P PG PGPPGPPG Sbjct: 627 QGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665 Score = 130 bits (327), Expect = 3e-30 Identities = 80/185 (43%), Positives = 94/185 (50%), Gaps = 39/185 (21%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGR-GPKGDPGSLGPLGPQG---------------PQGQ 500 GAPGPPG G +G++ V PV G GP G PG GP GP G P G+ Sbjct: 634 GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGE 693 Query: 501 PGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG---------PEGP 551 PG G +G GP GP+G G G+KGS G G G+PG G G PG P GP Sbjct: 694 PGIPG-IGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP 752 Query: 552 --PGSPGPSGPQGK------PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP-----G 598 PG PG G G+ PG+ G G+PG G GP+G+PG GPPG GPP G Sbjct: 753 GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812 Query: 599 PPGSQ 603 P G+Q Sbjct: 813 PRGAQ 817 Score = 130 bits (326), Expect = 5e-30 Identities = 74/159 (46%), Positives = 84/159 (52%), Gaps = 14/159 (8%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPG--SLGPLGPQGPQGQPGEAGPVGERGPV 513 RGA G PG G KG G +G G PKGDPG L G G G PG G GE GP+ Sbjct: 814 RGAQGLPGLNGLKGQQGRRGKTG---PKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPL 870 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 G RG+PG G G G G G G G IGPPGP G PG+PG G G PG+ G+ G+P Sbjct: 871 GQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTP 930 Query: 574 GQRGAMGPKGEP---------GIQGPPGLPGPPGPPGSQ 603 G +G G KG P G +G PGL G G PG + Sbjct: 931 GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEK 969 Score = 129 bits (325), Expect = 6e-30 Identities = 83/194 (42%), Positives = 90/194 (46%), Gaps = 49/194 (25%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGP------------QGQPGEA 504 G PG PG G KG+ G G +G G KG G +GP G +GP +G PG Sbjct: 303 GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP 362 Query: 505 GPVGERGPVGPR--------------------GFPGLKGSKGSFGTGG--PRGQPGPKGD 542 GP G RGP GP G+PGLKGSKG G G G PG G Sbjct: 363 GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGC 422 Query: 543 IGPPGPEGPPGSPGP-------SGPQGKPGIAGKTGSPGQRGAMGPKGEPG--------I 587 G PG G PG PGP GP G G+ G GSPG G GPKGEPG I Sbjct: 423 AGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYI 482 Query: 588 QGPPGLPGPPGPPG 601 GPPGLPG PG G Sbjct: 483 PGPPGLPGLPGLHG 496 Score = 125 bits (315), Expect = 9e-29 Identities = 71/159 (44%), Positives = 82/159 (51%), Gaps = 15/159 (9%) Query: 453 TILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 T + G PGPPGP G G G G G G GDPG GP G+PG G +G GP Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGL------PGPDGEPGIPG-IGFPGP 704 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP--------PGSPGPSGPQGKP 564 GP+G G G+KGS G G G+PG G G PG +G PG+PG G +G Sbjct: 705 PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNS 764 Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G G+ G PG G G G G+ GP G PG PGPPG Q Sbjct: 765 GEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQ 803 Score = 125 bits (314), Expect = 1e-28 Identities = 79/179 (44%), Positives = 89/179 (49%), Gaps = 36/179 (20%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG----- 511 G PGPPGPRG +G G GP G G PGS P G +G G PG G GERG Sbjct: 357 GTPGPPGPRGARGPQGPSGPPG---VPGSPGSSRP-GLRGAPGWPGLKGSKGERGRPGKD 412 Query: 512 PVGPRGFPGLKGSKGSFGTGGPRGQPG-------PKGDIGPPGPEGPPGSPGPSGPQGKP 564 +G G PG GS G G+ GP G PG P GD G PG G PG PG GP+G+P Sbjct: 413 AMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEP 472 Query: 565 GIA--------------------GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G+ G G PG++GA G KG PG G GLPG PG PG+Q Sbjct: 473 GLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531 Score = 125 bits (314), Expect = 1e-28 Identities = 72/163 (44%), Positives = 88/163 (53%), Gaps = 15/163 (9%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGP---KGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 +G GP G RG+ G+ G+ GP G G G PG++GP GP G G PG+ G G G Sbjct: 864 QGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGV 923 Query: 513 VGPRGFPGLKGSKGSFGTGGP---------RGQPGPKGDIGPPGPEGP---PGSPGPSGP 560 G RG PG KG +G G GP +G+PG KG G PG +G PG PG G Sbjct: 924 KGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGL 983 Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 +G PG AG G G G+ G GEPG++G PG G G PGS+ Sbjct: 984 KGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026 Score = 122 bits (307), Expect = 7e-28 Identities = 75/171 (43%), Positives = 84/171 (49%), Gaps = 26/171 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGP---VGGRGPKGDPGSLGPLGPQ---GPQGQPGEAGPVGER 510 G PG PG RG G GVKG G +G +GD G+ GP G +G+PG G G Sbjct: 907 GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP 966 Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------------PGSP 555 G G RG PG+ G KG G GP G PGP+GD+G G G PGS Sbjct: 967 GEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026 Query: 556 GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQ-----GPPGLPGPPGPPG 601 G G G PG AG+ G PG G G KGEPG GPPG G PG PG Sbjct: 1027 GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPG 1077 Score = 120 bits (300), Expect = 5e-27 Identities = 70/161 (43%), Positives = 80/161 (49%), Gaps = 17/161 (10%) Query: 463 GPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLK 522 G +G KG+ G GP G G KG G G GPQGP+G PG G G +G G G PG Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 523 GSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGA---- 578 GS G GT G G G G G G +G G PG G G PGI G G GQ+GA Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162 Query: 579 ----MGPKGEP---------GIQGPPGLPGPPGPPGSQSFY 606 + KG+P G+ GPPG PGP GPPG F+ Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFF 203 Score = 119 bits (299), Expect = 6e-27 Identities = 75/174 (43%), Positives = 84/174 (48%), Gaps = 24/174 (13%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEA--GPVGERGPVG 514 G PG PGP+G G G GPVG GP G G G +GP+GP+G GE G GERG G Sbjct: 174 GLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKG 233 Query: 515 PRGFPGLKGS--------------KGSFGTGGPRGQPGPKGDIGPPGP-----EGPPGSP 555 G PG G+ KG G G G+PGP G G PG +G PG P Sbjct: 234 LTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDP 293 Query: 556 GPSGPQGK---PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSFY 606 G G GK PG G G G RG G GE GI+G G GPPG G +Y Sbjct: 294 GLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYY 347 Score = 119 bits (298), Expect = 8e-27 Identities = 74/174 (42%), Positives = 84/174 (48%), Gaps = 28/174 (16%) Query: 457 GAPGPPGPRGF---------KGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV 507 G PGP GP+GF KG G+ G G G G PG+ G GP G G PG +G Sbjct: 70 GLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSK 129 Query: 508 GERG------PVGPRGFPGLKGSKGSFGTGG--------PRGQPGPKGDIGPPGPEGPPG 553 GE+G +G G PG G KG G +G PG G GP G GPPG Sbjct: 130 GEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPG 189 Query: 554 SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGE-----PGIQGPPGLPGPPGPPGS 602 PGP GP G PG G G+ G RG G GE G +G GL GPPGPPG+ Sbjct: 190 FPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGT 243 Score = 119 bits (297), Expect = 1e-26 Identities = 78/176 (44%), Positives = 92/176 (52%), Gaps = 28/176 (15%) Query: 455 LRGAPGPPGP-------RGFKGDMGVKGPVGGRG------PKGDPGSLGPLGPQ--GPQG 499 L G+PGPPGP +G GD G+ G +G G PKG+PG L P GP G Sbjct: 428 LPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPG 487 Query: 500 QPGEAGPVGERGPVGPRGFPGLKGSKGSFG-TG--------GPRGQPGPKGDIG----PP 546 PG G G +G G +G GLKGS GS G TG G +G PG KG+ G P Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPE 547 Query: 547 GPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G G PG PG G G+ G+ G G+PG +G GPKGE + G G GPPG PGS Sbjct: 548 GQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGS 603 Score = 119 bits (297), Expect = 1e-26 Identities = 67/148 (45%), Positives = 80/148 (54%), Gaps = 3/148 (2%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG---PVGERGPV 513 GA GPPGP G G G +G G G KG G+ G G QG +G PG + +G++G Sbjct: 898 GAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP 957 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 G +GF G G KG+ G G G G KG GP GP GP G G +G G+PG+ G GS Sbjct: 958 GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSM 1017 Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G G KG+ G G PG G PG PG Sbjct: 1018 GNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045 Score = 117 bits (294), Expect = 2e-26 Identities = 71/163 (43%), Positives = 81/163 (49%), Gaps = 18/163 (11%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGPVGER 510 G GPPG G G MG G +G GP G+PG+ G G +G +G PG G G++ Sbjct: 880 GILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDK 939 Query: 511 GPVGP---------RGFPGLKGSKGSFGTGGPR---GQPGPKGDIGPPGPEGPPGSPGPS 558 G GP +G PGLKG G+ G G R G PG KG G PGP GPPG G Sbjct: 940 GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999 Query: 559 GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G PG G G PG G MG G G +G G PG G PG Sbjct: 1000 GSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPG 1042 Score = 117 bits (293), Expect = 3e-26 Identities = 75/167 (44%), Positives = 87/167 (52%), Gaps = 32/167 (19%) Query: 444 QHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE 503 +HGEI G PG PG G G+ G+ GP +GDPG GP G QG PG Sbjct: 766 EHGEI--------GLPGLPGLPGTPGNEGLDGP------RGDPGQPGP---PGEQGPPGR 808 Query: 504 AGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPE-----GPPGSPGPS 558 GP G +G PGL G KG G RG+ GPKGD G PG + G GSPG Sbjct: 809 C----IEGPRGAQGLPGLNGLKGQ---QGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIP 861 Query: 559 GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP---GPPGPPGS 602 G QG+ G G+ G PG G +GP GE G+ G G P GPPGPPG+ Sbjct: 862 GHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGN 908 Score = 104 bits (259), Expect = 3e-22 Identities = 63/153 (41%), Positives = 74/153 (48%), Gaps = 36/153 (23%) Query: 457 GAPGPPGPRG------------------FKGDMGVKGPVGGRGP---KGDPGSLGPL--- 492 G PG PGPRG F G +G GP+G +GP +GDPG+L + Sbjct: 1298 GTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLP 1357 Query: 493 GPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP 552 G GP G PGE G GE GP GP G+ G GPRG+PG G PG GP Sbjct: 1358 GSPGPPGTPGEPGMQGEPGPPGP---------PGNLGPCGPRGKPGKD---GKPGTPGPA 1405 Query: 553 GSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEP 585 G G G +G+PG AG G PG +G G G P Sbjct: 1406 GEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438 Score = 75.5 bits (184), Expect = 1e-13 Identities = 41/92 (44%), Positives = 48/92 (52%), Gaps = 9/92 (9%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L G+PGPPG G G G GP PG G LGP GP+G+PG+ G G GP G Sbjct: 1356 LPGSPGPPGTPGEPGMQGEPGP---------PGPPGNLGPCGPRGKPGKDGKPGTPGPAG 1406 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPP 546 +G G KG G G+ G G G +GD G P Sbjct: 1407 EKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438 Score = 49.3 bits (116), Expect = 1e-05 Identities = 31/93 (33%), Positives = 39/93 (41%), Gaps = 12/93 (12%) Query: 455 LRGAPGPPGPRGFKGDMGVKG------------PVGGRGPKGDPGSLGPLGPQGPQGQPG 502 ++G PGPPGP G G G +G P G +G KG G GP G G G G Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKG 1430 Query: 503 EAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRG 535 + G G RGF + S+ + P G Sbjct: 1431 KRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEG 1463 >gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens] Length = 540 Score = 154 bits (388), Expect = 3e-37 Identities = 81/169 (47%), Positives = 96/169 (56%), Gaps = 23/169 (13%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVG------GRGPKGDPGSLGPLG---PQGPQGQPGEAGP 506 +GAPG GPRG +G G GP G RGP GD G GP G P GP+G+PG+ G Sbjct: 165 KGAPGDFGPRGDQGQDGAAGPPGPPGPPGARGPPGDTGKDGPRGAQGPAGPKGEPGQDGE 224 Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566 +G +GP GP+G PG+ G KG GT G PGPKG+ G GP G G G GP+G+PG Sbjct: 225 MGPKGPPGPKGEPGVPGKKGDDGTPSQPGPPGPKGEPGSMGPRGENGVDGAPGPKGEPGH 284 Query: 567 AGKTGSPGQRGAMGPKGEPG--------------IQGPPGLPGPPGPPG 601 G G+ G RGA G KGE G ++GPPG GPPGPPG Sbjct: 285 RGTDGAAGPRGAPGLKGEQGDTVVIDYDGRILDALKGPPGPQGPPGPPG 333 Score = 151 bits (382), Expect = 1e-36 Identities = 79/167 (47%), Positives = 94/167 (56%), Gaps = 21/167 (12%) Query: 456 RGAPGPPGPRG---FKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 RG PGPPG G + G +G+ G G GPKG+ G+ G GP+G QGQ G AGP G GP Sbjct: 132 RGDPGPPGQSGRDGYPGPLGLDGKPGLPGPKGEKGAPGDFGPRGDQGQDGAAGPPGPPGP 191 Query: 513 VGPRGFPG---LKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------------PGS 554 G RG PG G +G+ G GP+G+PG G++GP GP GP P Sbjct: 192 PGARGPPGDTGKDGPRGAQGPAGPKGEPGQDGEMGPKGPPGPKGEPGVPGKKGDDGTPSQ 251 Query: 555 PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 PGP GP+G+PG G G G GA GPKGEPG +G G GP G PG Sbjct: 252 PGPPGPKGEPGSMGPRGENGVDGAPGPKGEPGHRGTDGAAGPRGAPG 298 Score = 132 bits (332), Expect = 9e-31 Identities = 81/201 (40%), Positives = 92/201 (45%), Gaps = 54/201 (26%) Query: 457 GAPGPPGPRGF------KGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGER 510 G GPPGP+G KGD G G GPKG+PGS+GP G G G PG G G R Sbjct: 226 GPKGPPGPKGEPGVPGKKGDDGTPSQPGPPGPKGEPGSMGPRGENGVDGAPGPKGEPGHR 285 Query: 511 GP---VGPRGFPGLKGSKGSF--------------GTGGPRGQPGPKG------------ 541 G GPRG PGLKG +G G GP+G PGP G Sbjct: 286 GTDGAAGPRGAPGLKGEQGDTVVIDYDGRILDALKGPPGPQGPPGPPGIPGAKGELGLPG 345 Query: 542 ------DIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQ------- 588 + GP G +G PG PGP+G +G+ G G +G PG G G KGE Sbjct: 346 APGIDGEKGPKGQKGDPGEPGPAGLKGEAGEMGLSGLPGADGLKGEKGESASDSLQESLA 405 Query: 589 ------GPPGLPGPPGPPGSQ 603 GPPG PGPPGP G Q Sbjct: 406 QLIVEPGPPGPPGPPGPMGLQ 426 Score = 127 bits (320), Expect = 2e-29 Identities = 69/138 (50%), Positives = 78/138 (56%), Gaps = 18/138 (13%) Query: 482 PKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGL---KGSKGSFGTGGPRGQPG 538 P G PG G G +G G PG++G G GP+G G PGL KG KG+ G GPRG G Sbjct: 119 PPGPPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDGKPGLPGPKGEKGAPGDFGPRGDQG 178 Query: 539 PKGDIGPPGPEGPPGSPGP------SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPG 592 G GPPGP GPPG+ GP GP+G G AG G PGQ G MGPKG PG +G PG Sbjct: 179 QDGAAGPPGPPGPPGARGPPGDTGKDGPRGAQGPAGPKGEPGQDGEMGPKGPPGPKGEPG 238 Query: 593 LPG---------PPGPPG 601 +PG PGPPG Sbjct: 239 VPGKKGDDGTPSQPGPPG 256 Score = 125 bits (313), Expect = 1e-28 Identities = 68/157 (43%), Positives = 78/157 (49%), Gaps = 7/157 (4%) Query: 454 ILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPV 513 IL GPPGP+G G G+ G G G G PG G GP+G +G PGE GP G +G Sbjct: 315 ILDALKGPPGPQGPPGPPGIPGAKGELGLPGAPGIDGEKGPKGQKGDPGEPGPAGLKGEA 374 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDI-------GPPGPEGPPGSPGPSGPQGKPGI 566 G G GL G+ G G G + + GPPGP GPPG G G QG G+ Sbjct: 375 GEMGLSGLPGADGLKGEKGESASDSLQESLAQLIVEPGPPGPPGPPGPMGLQGIQGPKGL 434 Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G G G G GP G PG GPPGL G PG G + Sbjct: 435 DGAKGEKGASGERGPSGLPGPVGPPGLIGLPGTKGEK 471 Score = 125 bits (313), Expect = 1e-28 Identities = 74/165 (44%), Positives = 87/165 (52%), Gaps = 22/165 (13%) Query: 456 RGAPGPPGPRGFKGD---MGVKGPVGGRGPKGDPG---------SLGPL----GPQGPQG 499 +G PG PGP G KG+ MG+ G G G KG+ G SL L GP GP G Sbjct: 359 KGDPGEPGPAGLKGEAGEMGLSGLPGADGLKGEKGESASDSLQESLAQLIVEPGPPGPPG 418 Query: 500 QPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD---IGPPGPEGPPGSPG 556 P GP+G +G GP+G G KG KG+ G GP G PGP G IG PG +G G PG Sbjct: 419 PP---GPMGLQGIQGPKGLDGAKGEKGASGERGPSGLPGPVGPPGLIGLPGTKGEKGRPG 475 Query: 557 PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G PG G+ G +RG G +G PG +G G G PGPPG Sbjct: 476 EPGLDGFPGPRGEKGDRSERGEKGERGVPGRKGVKGQKGEPGPPG 520 Score = 106 bits (265), Expect = 5e-23 Identities = 63/152 (41%), Positives = 78/152 (51%), Gaps = 20/152 (13%) Query: 447 EILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP 506 E L + + G PGPPGP G G G++GP G G KG+ +G GE GP Sbjct: 402 ESLAQLIVEPGPPGPPGPPGPMGLQGIQGPKGLDGAKGE------------KGASGERGP 449 Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566 G GPVGP G GL G+KG +G+PG G G PGP G G G +G+ G+ Sbjct: 450 SGLPGPVGPPGLIGLPGTKGE------KGRPGEPGLDGFPGPRGEKGDRSERGEKGERGV 503 Query: 567 AGKTGSPGQRGAMGPKG--EPGIQGPPGLPGP 596 G+ G GQ+G GP G +P GP GLP P Sbjct: 504 PGRKGVKGQKGEPGPPGLDQPCPVGPDGLPVP 535 Score = 90.1 bits (222), Expect = 5e-18 Identities = 40/75 (53%), Positives = 47/75 (62%) Query: 529 GTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQ 588 G G RG+PG +GD GPPG G G PGP G GKPG+ G G G G GP+G+ G Sbjct: 121 GPPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDGKPGLPGPKGEKGAPGDFGPRGDQGQD 180 Query: 589 GPPGLPGPPGPPGSQ 603 G G PGPPGPPG++ Sbjct: 181 GAAGPPGPPGPPGAR 195 Score = 87.8 bits (216), Expect = 3e-17 Identities = 47/94 (50%), Positives = 52/94 (55%), Gaps = 3/94 (3%) Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572 V P G PG +G G G GP GQ G G GP G +G PG PGP G +G PG G G Sbjct: 117 VCPPGPPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDGKPGLPGPKGEKGAPGDFGPRGD 176 Query: 573 PGQRGAMGPKGEPG---IQGPPGLPGPPGPPGSQ 603 GQ GA GP G PG +GPPG G GP G+Q Sbjct: 177 QGQDGAAGPPGPPGPPGARGPPGDTGKDGPRGAQ 210 >gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens] Length = 1142 Score = 153 bits (387), Expect = 4e-37 Identities = 85/179 (47%), Positives = 102/179 (56%), Gaps = 32/179 (17%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP---LGPQGPQGQPGEAGPVGERGP 512 +G PG P +G KGD G G +G +G KG+PG GP +G G +GQ G AG +G RGP Sbjct: 479 KGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGP 538 Query: 513 VGPRGFP---------GLKGSKGS-FGTGGPRGQPGPKGDIGPPGP--------EGPPGS 554 G G P G+KG KG G GP G PGPKG+ GPPG +G PG+ Sbjct: 539 PGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGA 598 Query: 555 PGPSGPQGKPGIAGKTGS-----------PGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 PGP GP+G+ G+ G GS PG+ GA GP GEPGIQGP GLPG PG PG+ Sbjct: 599 PGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGT 657 Score = 138 bits (348), Expect = 1e-32 Identities = 76/167 (45%), Positives = 86/167 (51%), Gaps = 15/167 (8%) Query: 451 NVTILRGAPGPPGPRGFKGDMGVKGPV------------GGRGPKGDPGSLGPLGPQGPQ 498 NV G PGPPGP+G G +G G + G RGP G PG G G G Sbjct: 836 NVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAP 895 Query: 499 GQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS 558 G PG G GERGPVG GFPG +G G G G G PG +G +G PG GP G G Sbjct: 896 GPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQ 955 Query: 559 GPQGKPGIAGKTGSP---GQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G G G G+ G P G +GA+GP G PG +G G PG GPPGS Sbjct: 956 GIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGS 1002 Score = 135 bits (340), Expect = 1e-31 Identities = 80/181 (44%), Positives = 87/181 (48%), Gaps = 32/181 (17%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPG----------SL-------------GP 491 L G G PGP G KG+ G GP G GP G PG SL GP Sbjct: 784 LMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGP 843 Query: 492 LGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP 551 GP GP+G PG G G G G GFPG+KG +G G G G G G GPPG G Sbjct: 844 PGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGE 903 Query: 552 PGS---------PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 PG PGP GP GKPGI GK G PG +G MG G+ G +G G G PG GS Sbjct: 904 PGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGS 963 Query: 603 Q 603 Q Sbjct: 964 Q 964 Score = 132 bits (333), Expect = 7e-31 Identities = 71/146 (48%), Positives = 77/146 (52%), Gaps = 3/146 (2%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +G G PG G G G KG G G G PG G G QG +G GE G GE+G G Sbjct: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 GL G G G GP G PGPKG+ G GP GPP PG G QG G GK G G+ Sbjct: 351 PALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGR 410 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPG 601 RG GP G+P GPPG PGPPG G Sbjct: 411 RGKTGPPGKP---GPPGPPGPPGIQG 433 Score = 131 bits (330), Expect = 2e-30 Identities = 78/172 (45%), Positives = 86/172 (50%), Gaps = 26/172 (15%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG---PVGERGP 512 RG PG PG +G +G G+ G G GP G PG +G G GP G GE G P G+ GP Sbjct: 752 RGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGP 811 Query: 513 VGPRGFP-----------GLKGSKGSFGTGGPRGQPGPKGDIGP---------PGPEGPP 552 GP G P +KG GP G PGPKGD GP PG EG P Sbjct: 812 PGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFP 871 Query: 553 GSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPP---GLPGPPGPPG 601 G G GP G PGIAG +G PG G G GEPG +GP G PGP GP G Sbjct: 872 GVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSG 923 Score = 130 bits (328), Expect = 3e-30 Identities = 75/177 (42%), Positives = 90/177 (50%), Gaps = 31/177 (17%) Query: 450 RNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDP------GSLGPL----------- 492 R + L G PG PG G G G G GP GDP G +G L Sbjct: 646 RGLPGLPGTPGTPGNDGVPGR---DGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQAS 702 Query: 493 --------GPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIG 544 G +G G+PG+ + +G +GPRG PG+ G +G G+ G RG PG G+ G Sbjct: 703 VPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKG 762 Query: 545 PPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G +G PG PG GP G PG+ G+TG PG GA KGE G GPPG PGPPGPPG Sbjct: 763 DEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGA---KGEKGSDGPPGKPGPPGPPG 816 Score = 129 bits (325), Expect = 6e-30 Identities = 72/171 (42%), Positives = 86/171 (50%), Gaps = 25/171 (14%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDP------GSLGPL---------------- 492 L G PG PG G G G G G GP GDP G +G L Sbjct: 648 LPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLK 707 Query: 493 ---GPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPE 549 G +G G+PG+ + +G +GPRG PG+ G +G G+ G RG PG G+ G G + Sbjct: 708 SNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQ 767 Query: 550 GPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPP 600 G PG PG GP G PG+ G+TG PG GA G KG G G PG PGPPG P Sbjct: 768 GIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIP 818 Score = 120 bits (301), Expect = 4e-27 Identities = 69/167 (41%), Positives = 82/167 (49%), Gaps = 26/167 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G GPPGP+G KGD G GP G G G GP G +G +G+ G+ GP G+ GP GP Sbjct: 367 GPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPP 426 Query: 517 GFPGLKG--------------------SKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPG 556 G PG++G + G G G G PG G +GP G +G PG P Sbjct: 427 GPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPF 486 Query: 557 PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G + G G PG G+ G KGEPG GPPGL G PG G Q Sbjct: 487 TKGEK------GDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQ 527 Score = 120 bits (300), Expect = 5e-27 Identities = 79/207 (38%), Positives = 89/207 (42%), Gaps = 63/207 (30%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG-- 514 G PG PG RG GD+G GP G G G G G G QG G+PG+ GP GERG G Sbjct: 899 GVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIP 958 Query: 515 -------PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPG----------- 556 RG PGL G KG+ G P G PG KG +G PG +GPPGSPG Sbjct: 959 GDRGSQGERGKPGLTGMKGAIG---PMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSF 1015 Query: 557 ---------------------------------------PSGPQGKPGIAGKTGSPGQRG 577 GP GK G+ G G PG +G Sbjct: 1016 EEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQG 1075 Query: 578 AMGPKGEPGIQGPPGLPGPPGPPGSQS 604 G KGE G G GLPG PG PG+ + Sbjct: 1076 YRGQKGERGEPGI-GLPGSPGLPGTSA 1101 Score = 117 bits (293), Expect = 3e-26 Identities = 67/161 (41%), Positives = 74/161 (45%), Gaps = 11/161 (6%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +G G G G M KG +G RGP G PG GP G +G +G PG G G+ G G Sbjct: 710 KGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGI 769 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP----------- 564 G PG G G G G G PGP G G G +GPPG PGP GP G P Sbjct: 770 PGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLY 829 Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 I G P G GP G G GP G PG G PG + F Sbjct: 830 KIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGF 870 Score = 116 bits (291), Expect = 5e-26 Identities = 76/203 (37%), Positives = 89/203 (43%), Gaps = 59/203 (29%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L GAPG PG +G +G G KG G +G +G+ G G G G G+ GP GP G Sbjct: 317 LHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALAGLNGENGLKGDLGP---HGPPG 373 Query: 515 PRGF------PGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI-- 566 P+G PG GS G GP+G PG +G G G GPPG PGP GP G PGI Sbjct: 374 PKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQG 433 Query: 567 ---------------------------AGKTGSPGQRGAMGPK----------------- 582 G+TG PG G++GPK Sbjct: 434 IHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGD 493 Query: 583 -GEPGI---QGPPGLPGPPGPPG 601 GEPG+ QG G PG PGPPG Sbjct: 494 RGEPGVIGSQGVKGEPGDPGPPG 516 Score = 115 bits (288), Expect = 1e-25 Identities = 62/148 (41%), Positives = 78/148 (52%), Gaps = 18/148 (12%) Query: 477 VGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQ 536 + +G G PG+ G G +G +G+PGE G G G G +G G +GSKG G G +G+ Sbjct: 288 IPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGE 347 Query: 537 PGP------------KGDIGPPGPEGPPGSPGPSGPQGKP------GIAGKTGSPGQRGA 578 G KGD+GP GP GP G G +GP G P GI G G PG+ G Sbjct: 348 KGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQ 407 Query: 579 MGPKGEPGIQGPPGLPGPPGPPGSQSFY 606 G +G+ G G PG PGPPGPPG Q + Sbjct: 408 RGRRGKTGPPGKPGPPGPPGPPGIQGIH 435 Score = 114 bits (286), Expect = 2e-25 Identities = 78/218 (35%), Positives = 94/218 (43%), Gaps = 73/218 (33%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE------- 509 G GPPG G G+ G+ G G +G KGDPG G +GP G G GEAGP G+ Sbjct: 534 GPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG--GIIGPPGLPGPKGEAGPPGKSLPGEPG 591 Query: 510 ----------RGPVGPRGFPGLKGSKGSFG---------TG--GPRGQPG---PKGDIGP 545 RGP G RG PG+ GS G G TG GP G+PG P+G G Sbjct: 592 LDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGL 651 Query: 546 PGPEGPPGSPGPSGPQGKPGIAGK------------------------------------ 569 PG G PG+ G G GKPG+ G Sbjct: 652 PGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKG 711 Query: 570 ----TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G PG+ +M KG+ G +GPPG+PG GP GS+ Sbjct: 712 EEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSK 749 Score = 113 bits (283), Expect = 4e-25 Identities = 74/197 (37%), Positives = 87/197 (44%), Gaps = 51/197 (25%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGP--QGQPGEAGPVGERGPV 513 + PG PG G G G +GP G RG G GS G +GPQG G+ G GP GE G Sbjct: 584 KSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQ 643 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP------------------------- 548 GPRG PGL G+ G+ G G G+ G G GPPG Sbjct: 644 GPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASV 703 Query: 549 ---------EGPPGSPGPS---------GPQGKPGIAGKTGSPGQRGAM------GPKGE 584 EG G PG GP+G PGI G+ G G +G G KG+ Sbjct: 704 PGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGD 763 Query: 585 PGIQGPPGLPGPPGPPG 601 G+QG PG+PG PGP G Sbjct: 764 EGLQGIPGIPGAPGPTG 780 Score = 112 bits (281), Expect = 8e-25 Identities = 80/229 (34%), Positives = 91/229 (39%), Gaps = 87/229 (37%) Query: 457 GAPGPP---------GP---RGFKGDMGVKGPVGGRGPKGDPGS---LGPLGPQGPQGQP 501 GAPGPP GP GF G G G G G G PG+ +G G +GP+G+ Sbjct: 893 GAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGER 952 Query: 502 GEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS------- 554 G+ G G+RG G RG PGL G KG+ GP G PG KG +G PG +GPPGS Sbjct: 953 GDQGIPGDRGSQGERGKPGLTGMKGAI---GPMGPPGNKGSMGSPGHQGPPGSPGIPGIP 1009 Query: 555 ----------------------------------------------PGPSGPQGKPGIAG 568 PGP G G PG G Sbjct: 1010 ADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPG 1069 Query: 569 KTGSPGQRGAMGPKGEPGI----------------QGPPGLPGPPGPPG 601 G G RG G +GEPGI G PG PGP GPPG Sbjct: 1070 DPGPQGYRGQKGERGEPGIGLPGSPGLPGTSALGLPGSPGAPGPQGPPG 1118 Score = 109 bits (272), Expect = 8e-24 Identities = 68/184 (36%), Positives = 80/184 (43%), Gaps = 41/184 (22%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLG---PLGPQGPQGQPGEAGPVGERG 511 + G PG GP+G +GD G+ G G +G +G PG G +GP GP G G G G +G Sbjct: 939 IMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQG 998 Query: 512 PVGPRGFPGLKGSKGSF-----------------------------------GTGGPRGQ 536 P G G PG+ SF G G Sbjct: 999 PPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGP 1058 Query: 537 PGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRG--AMGPKGEPGIQGPPGLP 594 PG G GPPG GP G G G +G+PGI G GSPG G A+G G PG GP G P Sbjct: 1059 PGKDGLPGPPGDPGPQGYRGQKGERGEPGI-GLPGSPGLPGTSALGLPGSPGAPGPQGPP 1117 Query: 595 GPPG 598 GP G Sbjct: 1118 GPSG 1121 Score = 68.9 bits (167), Expect = 1e-11 Identities = 53/159 (33%), Positives = 64/159 (40%), Gaps = 49/159 (30%) Query: 452 VTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPG------------------------ 487 +T ++GA GP GP G KG MG G G G G PG Sbjct: 972 LTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFE 1031 Query: 488 -----------------SLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGT 530 + G GP G+ G GP G+ GP+G+ G KG +G G Sbjct: 1032 ERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGD---PGPQGYRGQKGERGEPGI 1088 Query: 531 GGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGK 569 G P G PG G G PGSPG GPQG PG +G+ Sbjct: 1089 GLP-GSPGLPG----TSALGLPGSPGAPGPQGPPGPSGR 1122 Score = 49.7 bits (117), Expect = 8e-06 Identities = 26/62 (41%), Positives = 30/62 (48%), Gaps = 10/62 (16%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVG----------GRGPKGDPGSLGPLGPQGPQGQPGEA 504 L G PG PGP+G++G G +G G G G PGS G GPQGP G G Sbjct: 1064 LPGPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRC 1123 Query: 505 GP 506 P Sbjct: 1124 NP 1125 >gi|48762934 alpha 2 type I collagen [Homo sapiens] Length = 1366 Score = 153 bits (386), Expect = 5e-37 Identities = 75/151 (49%), Positives = 85/151 (56%), Gaps = 6/151 (3%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE------AGPVGER 510 G PG G RG G +G GP G G +G+ G+ GP GP GP+G PGE AGP G Sbjct: 667 GNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFA 726 Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKT 570 GP G G PG KG +G+ G G G GP G +G GP GP G PGP+G +G G G T Sbjct: 727 GPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMT 786 Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G PG G GP G GI GPPG PGP G G Sbjct: 787 GFPGAAGRTGPPGPSGISGPPGPPGPAGKEG 817 Score = 152 bits (384), Expect = 9e-37 Identities = 77/145 (53%), Positives = 85/145 (58%), Gaps = 3/145 (2%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GAPGP GP G G G +G G GP G G++GP GP GPQG G+ G GE+GP R Sbjct: 961 GAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGP---R 1017 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G PGLKG G G G G G +G G GP GP G GPSGP GK G G G+ G Sbjct: 1018 GLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPA 1077 Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPG 601 G GP+G G GPPG PGPPGPPG Sbjct: 1078 GIRGPQGHQGPAGPPGPPGPPGPPG 1102 Score = 150 bits (380), Expect = 2e-36 Identities = 74/145 (51%), Positives = 80/145 (55%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GAPGP G G +G+ G GP G GP+G PG G +GP GP G G AG G+ G G R Sbjct: 682 GAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGER 741 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G G KG G G GP G GP G GPPGP G G GP G G PG AG+TG PG Sbjct: 742 GAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPS 801 Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPG 601 G GP G PG G GL GP G G Sbjct: 802 GISGPPGPPGPAGKEGLRGPRGDQG 826 Score = 147 bits (371), Expect = 3e-35 Identities = 75/150 (50%), Positives = 89/150 (59%), Gaps = 12/150 (8%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G GPPG RG G GV+GP G G G+PG +GP +G G PG GP G+ GPV Sbjct: 415 GVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGP---RGLPGSPGNIGPAGKEGPV--- 468 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP--- 573 G PG+ G G G G RG+P G+IG PGP+GP G PG +G +G G+AG G+P Sbjct: 469 GLPGIDGRPGPIGPAGARGEP---GNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPD 525 Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G GA GP G G+QG G GPPGPPG Q Sbjct: 526 GNNGAQGPPGPQGVQGGKGEQGPPGPPGFQ 555 Score = 144 bits (364), Expect = 2e-34 Identities = 75/150 (50%), Positives = 81/150 (54%), Gaps = 3/150 (2%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG GPRG G G GP G GP G PG G GP GP G GE G +G GP GP Sbjct: 442 GEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPT 501 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGD---IGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 G PG G KG G G RG PGP G+ GPPGP+G G G GP G PG G G Sbjct: 502 GDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPS 561 Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G G +G GE G+ G GLPGP GP G + Sbjct: 562 GPAGEVGKPGERGLHGEFGLPGPAGPRGER 591 Score = 143 bits (360), Expect = 5e-34 Identities = 82/184 (44%), Positives = 89/184 (48%), Gaps = 39/184 (21%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGR---------------GPKGDPGSLGPLGPQGPQGQP 501 GAPG PGPRG G +G G G R G KG+PGS GP GP GP G+ Sbjct: 319 GAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEE 378 Query: 502 GEAGPVGERGPVGPRGFPGLKGS------------------KGSFGTGGPRGQPGPKGDI 543 G+ GP GE G GP G PGL+GS GS G GP G GP GD Sbjct: 379 GKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDA 438 Query: 544 GPP------GPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP 597 G P GP G PGSPG GP GK G G G G+ G +GP G G G G PGP Sbjct: 439 GRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPK 498 Query: 598 GPPG 601 GP G Sbjct: 499 GPTG 502 Score = 142 bits (359), Expect = 7e-34 Identities = 72/153 (47%), Positives = 91/153 (59%), Gaps = 6/153 (3%) Query: 455 LRGAPGPPGPRGFKGDMGVKG------PVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG 508 L G+PG GP G +G +G+ G P+G G +G+PG++G GP+GP G PG+ G G Sbjct: 452 LPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKG 511 Query: 509 ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAG 568 G G RG PG G+ G+ G GP+G G KG+ GPPGP G G PGPSGP G+ G G Sbjct: 512 HAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPG 571 Query: 569 KTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 + G G+ G GP G G +GPPG G GP G Sbjct: 572 ERGLHGEFGLPGPAGPRGERGPPGESGAAGPTG 604 Score = 142 bits (358), Expect = 9e-34 Identities = 72/149 (48%), Positives = 85/149 (57%), Gaps = 3/149 (2%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PGP GPRG +G G G G GP G G GP GP G +G+PG G VG GP GP Sbjct: 580 GLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPS 639 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G PG +G+ G G G +G+PG +G+IG PG +G G+P G G PG AG TG G+ Sbjct: 640 GLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAP---GAVGAPGPAGATGDRGEA 696 Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 GA GP G G +G PG G GP G F Sbjct: 697 GAAGPAGPAGPRGSPGERGEVGPAGPNGF 725 Score = 142 bits (357), Expect = 1e-33 Identities = 74/158 (46%), Positives = 86/158 (54%), Gaps = 9/158 (5%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 ++G PG PG G G G +G G RG G PG G G G G G AGP+G GP G Sbjct: 197 VKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPG 256 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPP---GPEGPPGSPGPS------GPQGKPG 565 G PG KG G+ G GP G GP+G++G P GP GPPG+PG + G G PG Sbjct: 257 FPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPG 316 Query: 566 IAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 +AG G PG RG GP G G G GL G PGP GS+ Sbjct: 317 VAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSK 354 Score = 141 bits (355), Expect = 2e-33 Identities = 75/163 (46%), Positives = 87/163 (53%), Gaps = 18/163 (11%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GA G PGP+GF+G G G G GP G G GP G G G PG+ G GERG VGP+ Sbjct: 103 GAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQ 162 Query: 517 ---------GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA 567 G PG KG +G G G +GQPG G G PG G G+PG +G +G PG Sbjct: 163 GARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGER 222 Query: 568 GKTGSPGQRGA---------MGPKGEPGIQGPPGLPGPPGPPG 601 G+ G+PG GA +GP G G GPPG PG PGP G Sbjct: 223 GRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKG 265 Score = 141 bits (355), Expect = 2e-33 Identities = 77/156 (49%), Positives = 86/156 (55%), Gaps = 9/156 (5%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG---ERGP 512 RG GPPG GF G G GP G G G PG GP G +G +G G+ GPVG E G Sbjct: 777 RGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGA 836 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS------PGPSGPQGKPGI 566 VGP GF G KG G GT GP G PGP+G +G PG G PGS PG +G G+PG Sbjct: 837 VGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGP 896 Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G G PG RG G G PG+ G PG G G PG+ Sbjct: 897 LGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGN 932 Score = 140 bits (352), Expect = 4e-33 Identities = 72/158 (45%), Positives = 89/158 (56%), Gaps = 12/158 (7%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGPVGER 510 G GPPGP G G G++GP G +GP G G +G +GP +GP G+ G AGP G Sbjct: 802 GISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTP 861 Query: 511 GPVGPRGFPGL------KGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564 GP G G PG+ +G +G G G G+PGP G GPPG GPPG+ G G G P Sbjct: 862 GPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAP 921 Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G AG+ G+PG G G G+PG +G G PG GP G+ Sbjct: 922 GEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGA 959 Score = 138 bits (348), Expect = 1e-32 Identities = 67/147 (45%), Positives = 79/147 (53%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G GP GP G G+ G G GG+G KG+PG G +G G G G G VG GP G Sbjct: 631 GTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGAT 690 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G G G+ G G GPRG PG +G++GP GP G G G +G G G G G G+ Sbjct: 691 GDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGEN 750 Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G +GP G G GP G GPPGP GS+ Sbjct: 751 GVVGPTGPVGAAGPAGPNGPPGPAGSR 777 Score = 138 bits (347), Expect = 2e-32 Identities = 69/147 (46%), Positives = 80/147 (54%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +G GPPGP GF+G G GP G G G+ G G G GP G GE GP GE G GP Sbjct: 543 KGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGP 602 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 G G +G G G G +G+PG G +G GP GP G PG G G PG G+ G PG Sbjct: 603 TGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGL 662 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPGS 602 RG +G G G +G PG G PGP G+ Sbjct: 663 RGEIGNPGRDGARGAPGAVGAPGPAGA 689 Score = 137 bits (346), Expect = 2e-32 Identities = 75/148 (50%), Positives = 79/148 (53%), Gaps = 3/148 (2%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GAPGP G RG G +G GP G G G PG G GP+G G G AGP G GP G Sbjct: 226 GAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEV 285 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G PGL G G G G G G KG G PG G PG PGP G G G AG TG+ G Sbjct: 286 GLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLV 345 Query: 577 GAMGP---KGEPGIQGPPGLPGPPGPPG 601 G GP KGE G +G PG GP GPPG Sbjct: 346 GEPGPAGSKGESGNKGEPGSAGPQGPPG 373 Score = 137 bits (345), Expect = 3e-32 Identities = 74/156 (47%), Positives = 79/156 (50%), Gaps = 9/156 (5%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG GP GP GF G G G G +G +G G G G GP G G AGP G GP GP Sbjct: 714 RGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGP 773 Query: 516 ---RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572 RG G G G G G G PGP G GPPGP GP G G GP+G G G+TG Sbjct: 774 AGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGE 833 Query: 573 ------PGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 PG G GP GE G GPPG PGP G G+ Sbjct: 834 VGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGA 869 Score = 137 bits (345), Expect = 3e-32 Identities = 76/152 (50%), Positives = 81/152 (53%), Gaps = 9/152 (5%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G GPPGP G +GD GP G G G G GP GP G G PG GP G+ G GPR Sbjct: 766 GPNGPPGPAGSRGD---GGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPR 822 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G G G G G GP G G KG G G GPPG+PGP G G PGI G GS G+R Sbjct: 823 GDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGER 882 Query: 577 ------GAMGPKGEPGIQGPPGLPGPPGPPGS 602 GA+G G GI GPPG GPPG GS Sbjct: 883 GLPGVAGAVGEPGPLGIAGPPGARGPPGAVGS 914 Score = 136 bits (343), Expect = 5e-32 Identities = 68/146 (46%), Positives = 78/146 (53%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GAPG G G G+ G G G RG G+ G +G GP G +G G GPVG GP+G Sbjct: 193 GAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSA 252 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 G PG G+ G G G G GP G GP G G PG GP GP G PG G TG+ G Sbjct: 253 GPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAA 312 Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPGS 602 G G G PG+ GP G+PGP G G+ Sbjct: 313 GLPGVAGAPGLPGPRGIPGPVGAAGA 338 Score = 134 bits (337), Expect = 2e-31 Identities = 74/168 (44%), Positives = 89/168 (52%), Gaps = 21/168 (12%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGP---------QGPQGQPGEA 504 G PG PGP+G G +G GP G GP+G+ PG GP+GP G +G G Sbjct: 256 GFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLP 315 Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564 G G G GPRG PG G+ G+ G G G+PGP G G G +G PGS GP GP G Sbjct: 316 GVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPS 375 Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP---------GPPGSQ 603 G GK G G+ G+ GP G PG++G PG G P GPPGS+ Sbjct: 376 GEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSR 423 Score = 134 bits (336), Expect = 3e-31 Identities = 72/163 (44%), Positives = 81/163 (49%), Gaps = 16/163 (9%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPG----------------SLGPLGPQGPQG 499 RG GPPGP G G+ G GP G GP G PG GP+G GP+G Sbjct: 41 RGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRG 100 Query: 500 QPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSG 559 PG AG G +G GP G PG G G G GP G PG G+ G PG G PG G G Sbjct: 101 PPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVG 160 Query: 560 PQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 PQG G G G PG +G G G G++G PG PG G PG+ Sbjct: 161 PQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGA 203 Score = 132 bits (333), Expect = 7e-31 Identities = 72/148 (48%), Positives = 77/148 (52%), Gaps = 3/148 (2%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PGP GP G G G KG G G +G PG G G QGP G G G GE+GP GP Sbjct: 493 GFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPP 552 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576 GF GL G G G G G+ G G+ G PGP GP G GP G G G G GS G Sbjct: 553 GFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPS 612 Query: 577 GAMGP---KGEPGIQGPPGLPGPPGPPG 601 G GP KGEPG+ G G GP GP G Sbjct: 613 GPPGPDGNKGEPGVVGAVGTAGPSGPSG 640 Score = 132 bits (333), Expect = 7e-31 Identities = 73/161 (45%), Positives = 88/161 (54%), Gaps = 15/161 (9%) Query: 456 RGAPGPPGPRGFKGDMGVKGPV---GGRGPKGDPGSLGPLGPQGPQGQPGEA------GP 506 +G PGPPG +G G G G V G RG G+ G GP GP+G +G PGE+ GP Sbjct: 546 QGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGP 605 Query: 507 VGERGPVGP------RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGP 560 +G RGP GP +G PG+ G+ G+ G GP G PG +G G PG +G G PG G Sbjct: 606 IGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGE 665 Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G PG G G+PG GA GP G G +G G GP GP G Sbjct: 666 IGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAG 706 Score = 132 bits (332), Expect = 9e-31 Identities = 77/173 (44%), Positives = 90/173 (52%), Gaps = 27/173 (15%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE------ 509 +G G PG G KG G+ G G GP G+ G+ GP GPQG QG GE GP G Sbjct: 498 KGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGL 557 Query: 510 ---RGPVGPRGFPGLKGSKGSFGT---GGPRGQPGPKGDIGPPGPEGPPGSPGPSGP--- 560 GP G G PG +G G FG GPRG+ GP G+ G GP GP GS GPSGP Sbjct: 558 PGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGP 617 Query: 561 ---QGKPGIAGKTGS---------PGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 +G+PG+ G G+ PG+RGA G G G +G PGL G G PG Sbjct: 618 DGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPG 670 Score = 130 bits (328), Expect = 3e-30 Identities = 71/146 (48%), Positives = 78/146 (53%), Gaps = 3/146 (2%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RGA GP G RG GD G G G GP+G PGS G +GP G +G G G G GP+GP Sbjct: 423 RGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGP 482 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 G G G+ G G GP G PG GD G G G G+PGP G G G G G G Sbjct: 483 AGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGG 542 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPG 601 +G GP G PG Q GLPGP GP G Sbjct: 543 KGEQGPPGPPGFQ---GLPGPSGPAG 565 Score = 130 bits (327), Expect = 3e-30 Identities = 71/160 (44%), Positives = 82/160 (51%), Gaps = 15/160 (9%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG----------- 505 G GP GP G +G++G+ G G GP G+PG+ G G +G G PG AG Sbjct: 271 GNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIP 330 Query: 506 -PVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGK- 563 PVG G G RG G G GS G G +G+PG G GPPGP G G GP+G G Sbjct: 331 GPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSA 390 Query: 564 --PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 PG G GSPG RG G G G+ GPPG G GP G Sbjct: 391 GPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAG 430 Score = 130 bits (327), Expect = 3e-30 Identities = 70/150 (46%), Positives = 78/150 (52%), Gaps = 3/150 (2%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L G GPPG G G G KG G G G PG GP G GP G G G G G G Sbjct: 290 LSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPG 349 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGP---QGKPGIAGKTG 571 P G G G+KG G+ GP+G PGP G+ G GP G GS GP GP +G PG G G Sbjct: 350 PAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPG 409 Query: 572 SPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 + G+ G MGP G G GP G+ GP G G Sbjct: 410 ADGRAGVMGPPGSRGASGPAGVRGPNGDAG 439 Score = 130 bits (327), Expect = 3e-30 Identities = 73/160 (45%), Positives = 83/160 (51%), Gaps = 15/160 (9%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GA G G +G G GV G G GP+G PG +G G G +G GE GP G +G G + Sbjct: 301 GANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNK 360 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP---GSPGPSGPQGKPGIAGKTGSP 573 G PG G +G G G G+ GP G+ G GP GPP GSPG G G G AG G P Sbjct: 361 GEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPP 420 Query: 574 GQRGAMGP------------KGEPGIQGPPGLPGPPGPPG 601 G RGA GP GEPG+ GP GLPG PG G Sbjct: 421 GSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIG 460 Score = 129 bits (325), Expect = 6e-30 Identities = 71/151 (47%), Positives = 80/151 (52%), Gaps = 6/151 (3%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG PG G G G +G+ GP G RGP PG++G G G G+ G G G GP G Sbjct: 882 RGLPGVAGAVGEPGPLGIAGPPGARGP---PGAVGSPGVNGAPGEAGRDGNPGNDGPPGR 938 Query: 516 RGFPGLKGSKGSFGTGGP---RGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572 G PG KG +G G GP G PGP G +GP G G G GPSGP G G G G Sbjct: 939 DGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGP 998 Query: 573 PGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G +G G KGEPG +GP GLPG G G Q Sbjct: 999 SGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQ 1029 Score = 127 bits (318), Expect = 4e-29 Identities = 68/152 (44%), Positives = 78/152 (51%), Gaps = 16/152 (10%) Query: 463 GPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV-------------GE 509 GP G +G G +GP G G G+ G GP GP GP G PG G G Sbjct: 33 GPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGP 92 Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGK 569 G +GPRG PG G+ G G GP G+PG G GP G GP G PG +G G P GK Sbjct: 93 MGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHP---GK 149 Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G PG+RG +GP+G G G PGLPG G G Sbjct: 150 PGRPGERGVVGPQGARGFPGTPGLPGFKGIRG 181 Score = 126 bits (317), Expect = 5e-29 Identities = 73/158 (46%), Positives = 88/158 (55%), Gaps = 12/158 (7%) Query: 457 GAPGPPGPRGFKG---DMGVKGPVGGRGPKG---DPGSLGPLGPQGPQGQPGEAGPVGER 510 GA GPPG G KG + G GP G GP+G PG LG G +G +G PG AG VGE Sbjct: 835 GAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEP 894 Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP---GSPGPSGPQGKP--- 564 GP+G G PG +G G+ G+ G G PG G G PG +GPP G PG G +G P Sbjct: 895 GPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNI 954 Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G G G+PG G +GP G+ G +G G GP GP G+ Sbjct: 955 GPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGA 992 Score = 125 bits (315), Expect = 9e-29 Identities = 71/156 (45%), Positives = 80/156 (51%), Gaps = 9/156 (5%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 + G PG GP G G GV G G G G+PG+ GP G G G GE G G GPVG Sbjct: 899 IAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVG 958 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPP---GPEGPPGSPGPSGPQGKPGIAGKTG 571 G PG G G G G RG+ GP G +GP GP GP G G G +G+PG G G Sbjct: 959 AAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRG 1018 Query: 572 SPGQRGAMGPKGEPGI------QGPPGLPGPPGPPG 601 PG +G G +G PGI QG PG GP GP G Sbjct: 1019 LPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRG 1054 Score = 117 bits (293), Expect = 3e-26 Identities = 68/150 (45%), Positives = 77/150 (51%), Gaps = 28/150 (18%) Query: 474 KGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGS--------- 524 KGP G RGP+G+ G P GP G+ GE GP G GP GP G PGL G+ Sbjct: 32 KGPAGDRGPRGERG------PPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKG 85 Query: 525 ----KGSFGTGGPRGQPG------PKGDIGPPGPEGPPGSPGPS---GPQGKPGIAGKTG 571 G G GPRG PG P+G GP G G PG GP+ GP G PG AG+ G Sbjct: 86 VGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDG 145 Query: 572 SPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 PG+ G G +G G QG G PG PG PG Sbjct: 146 HPGKPGRPGERGVVGPQGARGFPGTPGLPG 175 Score = 108 bits (271), Expect = 1e-23 Identities = 58/124 (46%), Positives = 60/124 (48%), Gaps = 18/124 (14%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP------------------LGPQGPQ 498 G GP GP G G G GP G RG KG+PG GP G G Q Sbjct: 982 GPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQ 1041 Query: 499 GQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS 558 G PG GP G RGP GP G G G G GT GP G GP+G GP GP GPPG PGP Sbjct: 1042 GAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPP 1101 Query: 559 GPQG 562 G G Sbjct: 1102 GVSG 1105 Score = 97.8 bits (242), Expect = 3e-20 Identities = 57/134 (42%), Positives = 63/134 (47%), Gaps = 25/134 (18%) Query: 495 QGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGP--------------- 539 Q Q + GP G+RGP G RG PG G G G GP G PGP Sbjct: 23 QSLQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYD 82 Query: 540 -------KGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ---RGAMGPKGEPGIQG 589 G +G GP GPPG+ G GPQG G AG+ G PGQ GA GP G PG G Sbjct: 83 GKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAG 142 Query: 590 PPGLPGPPGPPGSQ 603 G PG PG PG + Sbjct: 143 EDGHPGKPGRPGER 156 Score = 82.4 bits (202), Expect = 1e-15 Identities = 49/133 (36%), Positives = 60/133 (45%), Gaps = 21/133 (15%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQ------GPQGQPGEAGPVGE 509 +G G PG +G G G+ G G G +G PGS+GP GP+ GP G+ G G G Sbjct: 1014 KGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGT 1073 Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGK 569 GP G R GP+G GP G GPPGP GPPG G G G + Sbjct: 1074 VGPAGIR---------------GPQGHQGPAGPPGPPGPPGPPGVSGGGYDFGYDGDFYR 1118 Query: 570 TGSPGQRGAMGPK 582 P ++ PK Sbjct: 1119 ADQPRSAPSLRPK 1131 Score = 76.6 bits (187), Expect = 6e-14 Identities = 39/83 (46%), Positives = 46/83 (55%), Gaps = 3/83 (3%) Query: 525 KGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP--GQRGAMGPK 582 KG G GPRG+ GP G G G +GP G PGP GP G PG+ G + G+ +GP Sbjct: 32 KGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGP- 90 Query: 583 GEPGIQGPPGLPGPPGPPGSQSF 605 G G+ GP G PG G PG Q F Sbjct: 91 GPMGLMGPRGPPGAAGAPGPQGF 113 >gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] Length = 1714 Score = 152 bits (385), Expect = 7e-37 Identities = 76/147 (51%), Positives = 89/147 (60%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L+G GPPGP GF GD+G+ G G GPKG G+ GP GP G +G GE GP+G G +G Sbjct: 760 LQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELG 819 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574 PRG PG KG G G G +G+ G +G+IG G GP G PG G G G G+ GSPG Sbjct: 820 PRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPG 879 Query: 575 QRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G KG G GPPG+PGP GP G Sbjct: 880 PLGPQGEKGVMGYPGPPGVPGPIGPLG 906 Score = 142 bits (358), Expect = 9e-34 Identities = 79/167 (47%), Positives = 88/167 (52%), Gaps = 21/167 (12%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG PG G +GFKG G G G RGP G GS G +G GP G PG G VG GP+GP Sbjct: 635 RGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGP 694 Query: 516 ------------RGFPGLKGSKGSFGTGGPRGQ---PGPKGDIGPPGPEGPPGSPGPSGP 560 +G PG+KG KG GT G G+ PG KG +G PGP G G GPSG Sbjct: 695 AGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQ 754 Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP------GPPGPPG 601 G PG+ G +G PG G G G PG GP G GPPGPPG Sbjct: 755 TGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPG 801 Score = 141 bits (356), Expect = 2e-33 Identities = 79/175 (45%), Positives = 95/175 (54%), Gaps = 30/175 (17%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG G G G G++G G G GDPG GP GP GP+G PG+ G G+ GP GP+ Sbjct: 729 GYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPK 788 Query: 517 GF---------PGLKGSKG------SFGTGGPRGQPGPKGDIGPPGPEGPPGSP------ 555 G PGLKG++G +FG GPRG+PG KG G PGPEG G Sbjct: 789 GLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNI 848 Query: 556 ---GPSGPQGKPGIAGKTGSPGQR------GAMGPKGEPGIQGPPGLPGPPGPPG 601 G +GP G PG G TGS G++ G +GP+GE G+ G PG PG PGP G Sbjct: 849 GKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIG 903 Score = 140 bits (352), Expect = 4e-33 Identities = 81/166 (48%), Positives = 96/166 (57%), Gaps = 24/166 (14%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP---LGPQGPQGQPGEAGPVGERGP- 512 G PGP GP G G +G +GP G +GPKG GS GP LG QG QG GE G G+RGP Sbjct: 897 GVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPH 956 Query: 513 --------VGPRGF---PGLKGSKGSFGTGGPRGQPGPKG---DIGPPGP---EGPPGSP 555 G RGF PGL+G GS G G G+PG +G D+GPPG EGPPG+ Sbjct: 957 GLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTE 1016 Query: 556 GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G SG QG+PG G G+ G ++G GEPG++G PG PG G G Sbjct: 1017 GESGLQGEPGAKGDVGTAG---SVGGTGEPGLRGEPGAPGEEGLQG 1059 Score = 138 bits (347), Expect = 2e-32 Identities = 78/162 (48%), Positives = 91/162 (56%), Gaps = 15/162 (9%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG---- 511 +G PG G G G G GP G +G G PGS G GP+G QG PG+ G G+RG Sbjct: 1314 QGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGA 1373 Query: 512 --PVGPRGFPGLKGSKGSFG----TG-----GPRGQPGPKGDIGPPGPEGPPGSPGPSGP 560 GP G PGLKG G +G TG GP+G G G +G GP+GP G G +GP Sbjct: 1374 QGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGP 1433 Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G+ GI G TG G RG G +GE G QGP G PGPPGPPG+ Sbjct: 1434 LGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGA 1475 Score = 135 bits (340), Expect = 1e-31 Identities = 71/151 (47%), Positives = 82/151 (54%), Gaps = 6/151 (3%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG----- 511 G+PG PG +G G G GP G +G G PG G LGP+G +G PG G G +G Sbjct: 594 GSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFP 653 Query: 512 -PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKT 570 G RG GL GS G G GP G PG +G +GP GP GP G PGP G G G+ G Sbjct: 654 GDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIK 713 Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G G++G G GEPG G G G PGPPG Sbjct: 714 GDKGEQGTAGELGEPGYPGDKGAVGLPGPPG 744 Score = 134 bits (337), Expect = 2e-31 Identities = 88/197 (44%), Positives = 100/197 (50%), Gaps = 51/197 (25%) Query: 456 RGAPGPPGPRGFKGDM---------------------GVKGPVGGRGPKGDPGSLGP--- 491 RG+PGP GP+G KG M G +GP G +GPKG GS GP Sbjct: 875 RGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGL 934 Query: 492 LGPQGPQGQPGEAGPVGERGP---------VGPRGF---PGLKGSKGSFGTGGPRGQPGP 539 LG QG QG GE G G+RGP G RGF PGL+G GS G G G+PG Sbjct: 935 LGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGL 994 Query: 540 K---GDIGPPGP---EGPPGSPGPSGPQGKPGI---------AGKTGSPGQRGAMGPKGE 584 + GD+GPPG EGPPG+ G SG QG+PG G TG PG RG G GE Sbjct: 995 RGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGE 1054 Query: 585 PGIQGPPGLPGPPGPPG 601 G+QG GL G PG G Sbjct: 1055 EGLQGKDGLKGVPGGRG 1071 Score = 132 bits (332), Expect = 9e-31 Identities = 75/168 (44%), Positives = 91/168 (54%), Gaps = 21/168 (12%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGP---------------KGDPGSLGPLGPQGPQGQP 501 G PGP G +G GD G G +G GP KG+ GS GPLGPQG +G Sbjct: 831 GEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVM 890 Query: 502 GEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQ---PGPKGDIGPPGPEGPPGSPGPS 558 G GP G GP+GP G PG G++G G+ GP+GQ GP G +G G +G G G Sbjct: 891 GYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQ 950 Query: 559 GPQGKPGIAGKTGSPGQRGAMGP---KGEPGIQGPPGLPGPPGPPGSQ 603 G +G G+ GKTG+PG+RG G +G PG G GLPG PG G Q Sbjct: 951 GKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQ 998 Score = 132 bits (331), Expect = 1e-30 Identities = 78/171 (45%), Positives = 85/171 (49%), Gaps = 22/171 (12%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRG------PKGDPGSLGPLGPQGPQGQPGEAGPVG 508 LRG PG PG G +G G+KG GGRG KG+ G G +GP G GQ G GP G Sbjct: 1045 LRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEG 1104 Query: 509 ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS---------PGPSG 559 G G RG PG KG KG G G G GP G IG GP+G G+ GP G Sbjct: 1105 IVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDG 1164 Query: 560 PQGKPGIAGKTGSPGQRGAMGPKGEPG-------IQGPPGLPGPPGPPGSQ 603 G PG G G PG G GPKGE G + GPPG G PGP G Q Sbjct: 1165 EPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQ 1215 Score = 132 bits (331), Expect = 1e-30 Identities = 72/160 (45%), Positives = 86/160 (53%), Gaps = 12/160 (7%) Query: 456 RGAPGP---------PGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP 506 RG PGP PG G+KG +GV G G G +G PG G G QG +G+ G G Sbjct: 1206 RGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGN 1265 Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS---PGPSGPQGK 563 G++G GP G PG+ G +G G G +G G G G PG GPPG PG G G+ Sbjct: 1266 KGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGR 1325 Query: 564 PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G+AG G PG +G+ G G PGIQGP G G PG PG Q Sbjct: 1326 TGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQ 1365 Score = 130 bits (327), Expect = 3e-30 Identities = 75/168 (44%), Positives = 91/168 (54%), Gaps = 21/168 (12%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQG------PQGQPGEAGPVGER 510 G G GP G G++G+ G +G +G +G PG LGP G +G P G PG GP+G Sbjct: 849 GKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLP 908 Query: 511 GPVGPRGFPGLKGSKGSFGTGGP---------RGQPGPKGDIGPPGPEG---PPGSPGPS 558 G VG RG PG +G KG G+ GP +G G KGD G GP G G+PG Sbjct: 909 GHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGER 968 Query: 559 GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQ---GPPGLPGPPGPPGSQ 603 G QGKPG+ G GS G RG G G G+Q GPPG G GPPG++ Sbjct: 969 GFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTE 1016 Score = 130 bits (326), Expect = 5e-30 Identities = 76/170 (44%), Positives = 88/170 (51%), Gaps = 15/170 (8%) Query: 447 EILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQP----- 501 E LR G PGPPGP G G G +GP G GP G+PG G GP+GP+G P Sbjct: 485 EYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPG 544 Query: 502 -------GEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS 554 G+ G G GP G +G GLKG G G G +G PG G+IG PG G G Sbjct: 545 QPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGL 604 Query: 555 PGPSGPQGKPGIAGKTGSPGQRGAMGPKGE---PGIQGPPGLPGPPGPPG 601 GP G G G G GSPG+ G +GP+GE PGI+G G G G PG Sbjct: 605 AGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPG 654 Score = 129 bits (324), Expect = 8e-30 Identities = 77/178 (43%), Positives = 89/178 (50%), Gaps = 31/178 (17%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP----LGPQGPQGQPGEAGPVGER 510 L G G PG G++G G GP G GPKG+ G G LGP GP+G+PG G GER Sbjct: 1159 LMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGER 1218 Query: 511 GPVGPRGF------------------PGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP 552 G G G+ PG G +G G G RG G KG G PGP G P Sbjct: 1219 GEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKP 1278 Query: 553 GSP------GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPP---GLPGPPGPPG 601 G P GP G QG G G +G+PG+ G G +G PGI+G P GL G PGPPG Sbjct: 1279 GIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPG 1336 Score = 129 bits (324), Expect = 8e-30 Identities = 73/177 (41%), Positives = 88/177 (49%), Gaps = 24/177 (13%) Query: 449 LRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGS------------LGPLGPQG 496 LR T +G PG PG +G +G G +G G +G KG PG LGP G QG Sbjct: 1235 LRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQG 1294 Query: 497 PQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPG 556 G G +G G+ GP G +G PG++G G G G G PG KG G PG G G G Sbjct: 1295 YHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKG 1354 Query: 557 PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPP------------GLPGPPGPPG 601 G G+PGI GK G G +G GP G+PG++G P G PGP GP G Sbjct: 1355 EQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEG 1411 Score = 129 bits (323), Expect = 1e-29 Identities = 72/153 (47%), Positives = 81/153 (52%), Gaps = 9/153 (5%) Query: 453 TILRGAPGPPGPRG---FKGDMGVKGPVGGRGPKGDPG------SLGPLGPQGPQGQPGE 503 T L GAPGPPG +G G G++GP G +G G PG G G QGP G PG Sbjct: 1326 TGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGL 1385 Query: 504 AGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGK 563 G GE G G GF G G KG G G G GPKG IG G GP G G GP G+ Sbjct: 1386 KGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGR 1445 Query: 564 PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGP 596 G G+ G G+ G GP+G+PG GPPG PGP Sbjct: 1446 TGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGP 1478 Score = 128 bits (322), Expect = 1e-29 Identities = 74/154 (48%), Positives = 82/154 (53%), Gaps = 9/154 (5%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G GP GP G G MG+ G G G KGD G G G G G PG+ G VG GP G R Sbjct: 687 GPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMR 746 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKG---DIGPP---GPEGPPGSPGPSGPQGKPGIAGKT 570 G G G G G GP G PGP+G DIG P GPEGP G G GP G PG+ G Sbjct: 747 GKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQ 806 Query: 571 GSPGQRGA---MGPKGEPGIQGPPGLPGPPGPPG 601 G G GA +GP+G+PG +G G PGP G G Sbjct: 807 GEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKG 840 Score = 128 bits (322), Expect = 1e-29 Identities = 71/154 (46%), Positives = 82/154 (53%), Gaps = 7/154 (4%) Query: 457 GAPGPPGPRGFKGDMG---VKGPVGGRGPKGDPGSLGP---LGPQGPQGQPGEAGPVGER 510 G PGP G G G G KG G GP G+ GS GP +G GP+G G G VG Sbjct: 1098 GLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHL 1157 Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP-GSPGPSGPQGKPGIAGK 569 G +GP G PG+ G +G G GP G PGPKG+ G PG + G PGP G G G G+ Sbjct: 1158 GLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGE 1217 Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G PG G G G PG++G G GPPG PG Q Sbjct: 1218 RGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQ 1251 Score = 128 bits (322), Expect = 1e-29 Identities = 73/156 (46%), Positives = 84/156 (53%), Gaps = 12/156 (7%) Query: 460 GPPGPRGFKG---DMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GPPGPRG G D G +G G G KG G G G G QG PGE G GE+G G R Sbjct: 1201 GPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGER 1260 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPP------GPEGPPGSPGPSGPQGKPGIAGKT 570 G G KG KG+ G G G PG +G +GP G +G G+PG GP GK G+ G Sbjct: 1261 GSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIR 1320 Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPP---GPPGSQ 603 G PG+ G G G PG++G GLPG P GP G Q Sbjct: 1321 GGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQ 1356 Score = 127 bits (318), Expect = 4e-29 Identities = 72/163 (44%), Positives = 84/163 (51%), Gaps = 15/163 (9%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG PG PG RG +GD+G G +G GP G G G G G +G G AG VG G G Sbjct: 986 RGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGL 1045 Query: 516 RGFPG------LKGSKGSFGTGGPRGQPGPKGD---------IGPPGPEGPPGSPGPSGP 560 RG PG L+G G G G RG PG G+ IGP G G G PGP G Sbjct: 1046 RGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGI 1105 Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G PG G+ G G +G +GP GE G +GPPG G GP G++ Sbjct: 1106 VGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGAR 1148 Score = 122 bits (305), Expect = 1e-27 Identities = 71/164 (43%), Positives = 85/164 (51%), Gaps = 19/164 (11%) Query: 457 GAPGPPG------PRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGER 510 G+ GPPG P+G +G G G +G GP G+PG G G QG G G GP GE+ Sbjct: 1131 GSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEK 1190 Query: 511 G----------PVGPRGFPGL---KGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP 557 G P GPRG PG +G +G G G +G G G G G +GPPG PG Sbjct: 1191 GYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGD 1250 Query: 558 SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G QG G G G+ G++GA GP G+PGI G GL GP G G Sbjct: 1251 QGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQG 1294 Score = 121 bits (303), Expect = 2e-27 Identities = 70/154 (45%), Positives = 83/154 (53%), Gaps = 9/154 (5%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG PGP+G KGD G G KGD G G +GP G QG G G G G G + Sbjct: 525 GLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQ 584 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP------GPSGPQGKPGIAGKT 570 G PG G+ GS G G +G GP+G+ GP G +G GSP GP G +G PGI GK Sbjct: 585 GIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKK 644 Query: 571 GSPGQR---GAMGPKGEPGIQGPPGLPGPPGPPG 601 G G++ G G +G G+ G PGL G GPPG Sbjct: 645 GFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPG 678 Score = 120 bits (300), Expect = 5e-27 Identities = 67/159 (42%), Positives = 80/159 (50%), Gaps = 12/159 (7%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L G G PG +G KG+ G G +G G GD G++G GP G +G+ G +G G+ G G Sbjct: 703 LSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQG 762 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS------------GPQG 562 P G PG +G G G G G GPKG +G GP GPPG G GP+G Sbjct: 763 PSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRG 822 Query: 563 KPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 KPG G G PG G G G+ G G G GP G PG Sbjct: 823 KPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPG 861 Score = 115 bits (288), Expect = 1e-25 Identities = 71/175 (40%), Positives = 86/175 (49%), Gaps = 27/175 (15%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGP---------------KGDPGSLGPLGPQGPQGQ 500 RG G G +G +G G KG G RGP +G PG G G G +G Sbjct: 929 RGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGL 988 Query: 501 PGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDI---------GPPGPEGP 551 PGE G G +G VGP G G++G G+ G G +G+PG KGD+ G PG G Sbjct: 989 PGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGE 1048 Query: 552 PGSPGPSGPQGKPGIAGKTGS---PGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 PG+PG G QGK G+ G G PG+ G G G PGI GP G G G PG + Sbjct: 1049 PGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPE 1103 Score = 111 bits (278), Expect = 2e-24 Identities = 66/132 (50%), Positives = 72/132 (54%), Gaps = 6/132 (4%) Query: 480 RGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGG-PRGQ-- 536 RGPKGD G GP GP G G G+ GP G GP G G PGL G KG G G GQ Sbjct: 488 RGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPV 547 Query: 537 PGPKGDIGPPGPEGPPGSPGPSGPQGK---PGIAGKTGSPGQRGAMGPKGEPGIQGPPGL 593 PG KGD G G GPPG G G +G PG+ G+ G PG G +G G PG QG G Sbjct: 548 PGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGP 607 Query: 594 PGPPGPPGSQSF 605 G PGP G+Q F Sbjct: 608 EGNPGPKGAQGF 619 Score = 105 bits (262), Expect = 1e-22 Identities = 58/125 (46%), Positives = 67/125 (53%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 L G PG G RG +G G +GP G G KG PG G G G QG PG GP G+ G VG Sbjct: 1358 LPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVG 1417 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574 G G G +G+ G G G GP G GP G +G G GP GP+G+PG G G+PG Sbjct: 1418 ISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPG 1477 Query: 575 QRGAM 579 R M Sbjct: 1478 PRKQM 1482 Score = 82.0 bits (201), Expect = 1e-15 Identities = 47/106 (44%), Positives = 57/106 (53%), Gaps = 16/106 (15%) Query: 444 QHGEI-LRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG 502 Q GE ++ +T +G PGP GP G G +G+ GP +GP G G+ GPLG +G G G Sbjct: 1388 QPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGP---KGPIGHRGNTGPLGREGIIGPTG 1444 Query: 503 EAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548 GP GE KG +G G GPRGQPGP G G PGP Sbjct: 1445 RTGPRGE------------KGFRGETGPQGPRGQPGPPGPPGAPGP 1478 >gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] Length = 1669 Score = 152 bits (384), Expect = 9e-37 Identities = 81/151 (53%), Positives = 89/151 (58%), Gaps = 6/151 (3%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +G PG PGPRG G G KG G G G+PG G +G QGPQG+ GEAGP G G V Sbjct: 277 KGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIG 336 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 G G KG +G GT GPRG+PGPKG G PG GPPG P P G G PG G+ G G Sbjct: 337 TGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVP-GQAGAPGFPGERGEKGD 395 Query: 576 RG-----AMGPKGEPGIQGPPGLPGPPGPPG 601 RG GP G G+ GPPG PGPPG PG Sbjct: 396 RGFPGTSLPGPSGRDGLPGPPGSPGPPGQPG 426 Score = 142 bits (357), Expect = 1e-33 Identities = 75/157 (47%), Positives = 82/157 (52%), Gaps = 10/157 (6%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG GP G +G G KG G G G G+ GP G G G PG G G+ GP GP Sbjct: 61 GFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPP 120 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP----------SGPQGKPGI 566 G PG G+KG G GP G PG G+ GPPG G G PG G +G PGI Sbjct: 121 GIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGI 180 Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G G PG G GP G PG GPPG PGPPGPPG + Sbjct: 181 PGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEK 217 Score = 142 bits (357), Expect = 1e-33 Identities = 81/174 (46%), Positives = 91/174 (52%), Gaps = 27/174 (15%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSL--GPLGPQGPQGQPGEAGPVGERGP 512 L G+PG PG +G +G MG GP G G G PG GP G +GPQGQPG G G GP Sbjct: 1196 LAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGP 1255 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGD---------------IGPPGPEGPPGSPGP 557 G G G+KG KG+ G G G PGPKGD G G GPPG PG Sbjct: 1256 PGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGF 1315 Query: 558 SGPQGKPGIAGKTGSPGQRGAMGPKGEPG----------IQGPPGLPGPPGPPG 601 GP+G PG+ G G G +G G KG PG I+G PGLPGP GPPG Sbjct: 1316 QGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPG 1369 Score = 139 bits (351), Expect = 6e-33 Identities = 78/163 (47%), Positives = 82/163 (50%), Gaps = 9/163 (5%) Query: 449 LRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG 508 L +T G PG PG +G G G G G G G PG G GP G G PGE G G Sbjct: 850 LPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHG 909 Query: 509 ERGPVGPRGFPGLKGSKGSFGTGGPRGQ---------PGPKGDIGPPGPEGPPGSPGPSG 559 G GPRG PGLKG KG G G G G KGD G G GP G G G Sbjct: 910 FPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRG 969 Query: 560 PQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G PG+ GK G GQ G GPKG+PGI G PG PG PGP GS Sbjct: 970 DPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGS 1012 Score = 139 bits (351), Expect = 6e-33 Identities = 89/196 (45%), Positives = 98/196 (50%), Gaps = 46/196 (23%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG------------ 502 L G PGP GP G G GVKG G G G PG GP G G QG PG Sbjct: 1246 LPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKG 1305 Query: 503 EAGPVGERGPVGPRGFPGLKGSKG---------SFGTGGPRGQPGP----KGDIGPPGPE 549 + GP G G GP+G PGL+G KG + G GP G PGP KG+ G PGPE Sbjct: 1306 DMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPE 1365 Query: 550 GPP------GSPGPSGPQ---------GKPGIAGKTGSPGQRGAM------GPKGEPGIQ 588 GPP G PGP G Q G PGI G G+PGQ+G M GP+G PG Sbjct: 1366 GPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPP 1425 Query: 589 GPPGLPGPPGPPGSQS 604 GP GLPG GPPG+ S Sbjct: 1426 GPDGLPGSMGPPGTPS 1441 Score = 139 bits (349), Expect = 1e-32 Identities = 75/155 (48%), Positives = 82/155 (52%), Gaps = 8/155 (5%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG--------EAGPVG 508 G PG G +G KG++G G G G G G G +GP GPQGQPG GP G Sbjct: 1177 GFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKG 1236 Query: 509 ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAG 568 +RGP G G PGL G G G G G G KG+ G PG G PG G G QG PGI G Sbjct: 1237 DRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGG 1296 Query: 569 KTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 G G +G MGP G PG QGP GLPG G G Q Sbjct: 1297 SPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQ 1331 Score = 133 bits (335), Expect = 4e-31 Identities = 84/196 (42%), Positives = 96/196 (48%), Gaps = 49/196 (25%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE---AGPVGERGPV 513 G+PG PG +G KG G+ G G +G G PG+ GP GP G +G+PG G GE+G Sbjct: 1109 GSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEP 1168 Query: 514 G--PRGFPGL------KGSKGS---------------------FGTGGPRGQP------- 537 G RGFPG KGSKG G GP+GQP Sbjct: 1169 GLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPG 1228 Query: 538 ----GPKGDIGPPGPEGPPGSPGPSGPQGKPGI------AGKTGSPGQRGAMGPKGEPGI 587 GPKGD GP G G PG PGP GP G PGI G G PG G GPKG+PG Sbjct: 1229 HATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGF 1288 Query: 588 QGPPGLPGPPGPPGSQ 603 QG PG+ G PG GS+ Sbjct: 1289 QGMPGIGGSPGITGSK 1304 Score = 133 bits (334), Expect = 5e-31 Identities = 78/178 (43%), Positives = 89/178 (50%), Gaps = 29/178 (16%) Query: 457 GAPGPPGP---------RGFKGDMGVKG---PVGGRGPKGDPGSLGPLGPQGPQGQPGEA 504 G PG PG +G KGD G KG P+G +G +GDPG+ G G G GQPG+ Sbjct: 930 GLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQP 989 Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564 GP G+ G G G PGL G KGS G G G PG KG G PGP+G PG PG G +G+ Sbjct: 990 GPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEK 1049 Query: 565 GIAGK-----------------TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 G AG G PG G G KG GI G PG PG G PGS + Sbjct: 1050 GQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGY 1107 Score = 132 bits (332), Expect = 9e-31 Identities = 78/169 (46%), Positives = 87/169 (51%), Gaps = 24/169 (14%) Query: 457 GAPGPPGPRGFKGDMGV--------KGPVGGRGPKGDPGSL-----GPLGPQGPQGQPGE 503 G PGPPGP G KG MG+ KG G GP G PG G +G +GQ GE Sbjct: 206 GPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGE 265 Query: 504 --------AGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP 555 G GE G GPRG PG G KG G+ G G+PG G IG GP+G G Sbjct: 266 PGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEA 325 Query: 556 GPSGPQG---KPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 GP GP G G G+ G G G GP+GEPG +G PGLPG PGPPG Sbjct: 326 GPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPG 374 Score = 129 bits (325), Expect = 6e-30 Identities = 76/176 (43%), Positives = 86/176 (48%), Gaps = 31/176 (17%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP---- 512 G GPPGP G G G KG G GP G PG G GP G G G+ G + P Sbjct: 112 GQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLL 171 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP-----------GPSGPQ 561 G RGFPG+ G+ G G G +G GP G GPPGP GPPG P GP G + Sbjct: 172 KGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDK 231 Query: 562 GKPGIAGKTGSPGQ-----------RGAMGPKGEPGIQGPPGL-----PGPPGPPG 601 G G++G G PGQ +G G KGEPG QG PG+ PG PGP G Sbjct: 232 GDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRG 287 Score = 129 bits (324), Expect = 8e-30 Identities = 87/202 (43%), Positives = 102/202 (50%), Gaps = 42/202 (20%) Query: 444 QHGE--ILRNVTILRGAPGPPGPR---GFKGDMGVKGPVG--GR-------GPKGDPGSL 489 Q GE ++ ++ RG PGP GP GF G G KG G GR GP+G PG + Sbjct: 462 QKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLI 521 Query: 490 GPLGPQGPQGQ----------------PGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGP 533 G G +G G+ PG+ G G G G G PGL G KGS G+ G Sbjct: 522 GQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGL 581 Query: 534 RGQPGPKGDIGPPGPE---GPPGSP--GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPG-- 586 +G+ GP G +G PG GPPG P GP+GP G G AG G PG G GPKGEPG Sbjct: 582 KGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKI 641 Query: 587 --IQGPP---GLPGPPGPPGSQ 603 + GPP GLPG PG PG Q Sbjct: 642 VPLPGPPGAEGLPGSPGFPGPQ 663 Score = 129 bits (324), Expect = 8e-30 Identities = 75/152 (49%), Positives = 82/152 (53%), Gaps = 5/152 (3%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG PG G G G++G G GP G PGS+G G G G PG GP G +GP G Sbjct: 761 GVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGI-GPPGARGPPGGQGPPGLS 819 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGP---PGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 G PG+KG KG G G PGPKGD G PG G G PG G QG PGI G GS Sbjct: 820 GPPGIKGEKGFPGFPG-LDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSK 878 Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 G+ G MG G+PG GP G PG PG G F Sbjct: 879 GEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGF 910 Score = 129 bits (323), Expect = 1e-29 Identities = 80/175 (45%), Positives = 88/175 (50%), Gaps = 29/175 (16%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PG PG G G G G G GPKG PGS+G G +GP PG G G RG GP Sbjct: 547 GFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGP---PGGVGFPGSRGDTGPP 603 Query: 517 GFPGL--------KGSKGSFGTGGPRGQPGPKGD-------IGPPGPEGPPGSPGPSGPQ 561 G PG KG G G G G PGPKG+ GPPG EG PGSPG GPQ Sbjct: 604 GPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQ 663 Query: 562 GK---PGIAGKTGSPGQRGAM--------GPKGEPGIQGPPGLPGPPGPPGSQSF 605 G PG G+ G PG++GA+ GP G G+ G PG GPPG PG F Sbjct: 664 GDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGF 718 Score = 128 bits (322), Expect = 1e-29 Identities = 80/189 (42%), Positives = 96/189 (50%), Gaps = 29/189 (15%) Query: 446 GEILRNVTIL-----RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQ 500 GEIL +V + RG PG PG G G G++GPVG G G PG GP GP G +GQ Sbjct: 160 GEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQ 219 Query: 501 PGEA--GPVGERGPVGPRGFPGLKG-----SKGSFGTGGPRGQP-----------GPKGD 542 G + GP G++G G G PG+ G KG F T G +GQ G KG+ Sbjct: 220 MGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGE 279 Query: 543 IGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP------GP 596 G PGP G PG G G +G PG G+ G PG G GP+GE G GPPG P GP Sbjct: 280 PGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGP 339 Query: 597 PGPPGSQSF 605 G G + + Sbjct: 340 LGEKGERGY 348 Score = 128 bits (322), Expect = 1e-29 Identities = 70/170 (41%), Positives = 88/170 (51%), Gaps = 23/170 (13%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGG------------RGPKGDPGSLGPLGPQGPQGQPGEA 504 G G PG +G KGD+G+ G G +G +G+ G +GP+G +G +G PG Sbjct: 915 GPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTP 974 Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGP---PGPEGPPGSPGPSGPQ 561 G G+ G G G PG KG G GT G G PGPKG +G PG G G PG GPQ Sbjct: 975 GVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQ 1034 Query: 562 GKPGIAGKTGSPGQRGAMGP--------KGEPGIQGPPGLPGPPGPPGSQ 603 G PG+ G G+ G++G GP +GE G QG G PG PG G + Sbjct: 1035 GSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEK 1084 Score = 128 bits (322), Expect = 1e-29 Identities = 73/150 (48%), Positives = 83/150 (55%), Gaps = 11/150 (7%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GAPG PGP+G G MG+ G G KG PG GPQG G PG+ G GE+G GP Sbjct: 1002 GAPGLPGPKGSVGGMGLPGTPG---EKGVPGI---PGPQGSPGLPGDKGAKGEKGQAGPP 1055 Query: 517 --GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574 G PGL+G KG G G G PG KG+ G G G PGSPG G G G G G PG Sbjct: 1056 GIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPG 1115 Query: 575 Q---RGAMGPKGEPGIQGPPGLPGPPGPPG 601 + +G G G PG++G GLPG PGP G Sbjct: 1116 EKGDKGLPGLDGIPGVKGEAGLPGTPGPTG 1145 Score = 128 bits (321), Expect = 2e-29 Identities = 76/161 (47%), Positives = 84/161 (52%), Gaps = 15/161 (9%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGD--PGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 G PGP G G GD G KG G GP G PG G G QG G PG G GE+G +G Sbjct: 1029 GIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIG 1088 Query: 515 PRGFPG---LKGSKGSFGTGGPRGQPGPKGDIGPPGPE---------GPPGSPGPSGPQG 562 G PG LKGS GS G G G PG KGD G PG + G PG+PGP+GP G Sbjct: 1089 IPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAG 1148 Query: 563 KPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 + G G G PG G G G PG +G PG PG G GS+ Sbjct: 1149 QKGEPGSDGIPGSAGEKGEPGLPG-RGFPGFPGAKGDKGSK 1188 Score = 127 bits (318), Expect = 4e-29 Identities = 78/173 (45%), Positives = 89/173 (51%), Gaps = 29/173 (16%) Query: 457 GAPGPPGPRGFKGDMGVKGPVG--GR-------------GPKGDPGSLGPLGPQGPQGQP 501 G PGPPGP+G G G GP G GR G KG+PG +G G +G G P Sbjct: 690 GFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPG-VGLPGLKGLPGLP 748 Query: 502 GEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKG-----------DIGPPGPEG 550 G G GE+G +G G PG G+ G G G RG+PGP G IGPPG G Sbjct: 749 GIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARG 808 Query: 551 PPGSPGPSGPQGKPGIAGKTGSPGQRG--AMGPKGEPGIQGPPGLPGPPGPPG 601 PPG GP G G PGI G+ G PG G GPKG+ G QG PG+ G G PG Sbjct: 809 PPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPG 861 Score = 127 bits (318), Expect = 4e-29 Identities = 77/179 (43%), Positives = 86/179 (48%), Gaps = 32/179 (17%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG------------EA 504 G+PGP G G G+ G G G GP+GDPG G G G G+PG + Sbjct: 891 GSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQK 950 Query: 505 GPVGERGPVGP------RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS 558 G GE+G +GP RG PG G G G G GQPGPKGD G G G PG PGP Sbjct: 951 GDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPK 1010 Query: 559 ------------GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPP--GLPGPPGPPGSQ 603 G +G PGI G GSPG G G KGE G GPP G+PG G G Q Sbjct: 1011 GSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQ 1069 Score = 125 bits (313), Expect = 1e-28 Identities = 80/178 (44%), Positives = 89/178 (50%), Gaps = 27/178 (15%) Query: 455 LRGAPGPPGP---RGFKGDMGVKGPVGGRGPKGDP--GSLGPLGPQGPQGQPGEAGPVGE 509 L G+PG PGP RGF G G G G +G G P G GP GP+G G PG+ GP G Sbjct: 653 LPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGT 712 Query: 510 RGPVGPRGF---PGLKGSKGSFGTG-----------GPRGQPGPKGDIGPPGPE------ 549 G G G PG++G KG G G G G PG KG IG PG Sbjct: 713 PGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAI 772 Query: 550 GPPGSPGPSGPQGKPGIAGKTGSPGQR--GAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 GPPG G G G PG+ G GSPG G G +G PG QGPPGL GPPG G + F Sbjct: 773 GPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGF 830 Score = 124 bits (312), Expect = 2e-28 Identities = 76/167 (45%), Positives = 86/167 (51%), Gaps = 19/167 (11%) Query: 455 LRGAPGPPGPRGFKG-DMGV----KGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV-- 507 L G PG PGP G G G+ GP G +GP G PG G +G G +GQ GE+ + Sbjct: 412 LPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICD 471 Query: 508 --GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP- 564 G RGP GP+G PG G G G G RG PG G G PGP+G PG G G +G+P Sbjct: 472 IDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPG 531 Query: 565 ---------GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G G G PGQ G G G PG G PGLPGP G PGS Sbjct: 532 EFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGS 578 Score = 124 bits (311), Expect = 3e-28 Identities = 83/195 (42%), Positives = 96/195 (49%), Gaps = 52/195 (26%) Query: 457 GAPGPPG--PRGFKGDMGVKGPVGGRG------PKGDPGSL----GPLGPQGPQGQPGEA 504 G PGPPG P G GD G G GG G PKG+PG + GP G +G G PG Sbjct: 601 GPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFP 660 Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPR--GQPGPKG------DIGPPGPEGPPG--- 553 GP G+RG G G PGL G KG+ G G G PGPKG D+GPPG G PG Sbjct: 661 GPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNG 720 Query: 554 ---SPGPSGPQGKPGIA-----------------------GKTGSPGQRGAMGPKGEPGI 587 +PG G +G+PG+ G G PG+ GA+GP PG+ Sbjct: 721 LPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGP---PGL 777 Query: 588 QGPPGLPGPPGPPGS 602 QG G PGPPG PGS Sbjct: 778 QGIRGEPGPPGLPGS 792 Score = 123 bits (309), Expect = 4e-28 Identities = 71/158 (44%), Positives = 86/158 (54%), Gaps = 10/158 (6%) Query: 455 LRGAPGPPGPRGFKGDMGVKG--PVGGRGP---KGDPGSLGPLGPQGPQGQPGEAG--PV 507 +RG PGPPG G G GV G P G RGP +G PG GP G +G +G PG G Sbjct: 780 IRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMP 839 Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKG---DIGPPGPEGPPGSPGPSGPQGKP 564 G +G G +G PG+ G G G G +G PG G G G G PG PG GP G P Sbjct: 840 GPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAP 899 Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G+ G+ G G G+ GP+G+PG++G G G PG PGS Sbjct: 900 GLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGS 937 Score = 123 bits (309), Expect = 4e-28 Identities = 73/180 (40%), Positives = 87/180 (48%), Gaps = 35/180 (19%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPG-----SLGPLGPQGPQGQPGEAGPVG--- 508 G PG GP G +G G+ GP G +G KG PG GP G +G QG PG G G Sbjct: 802 GPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPG 861 Query: 509 ---ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPG 565 ++G G GFPG KG G GT G G PGP G G PG +G G PG SGP+G PG Sbjct: 862 LPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPG 921 Query: 566 IAG------------------------KTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 + G + G G++G +GP GE G +G PG PG PG G Sbjct: 922 LKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDG 981 Score = 122 bits (307), Expect = 7e-28 Identities = 67/146 (45%), Positives = 78/146 (53%), Gaps = 4/146 (2%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +G+ G PG G G G G G GPKGDPG G G G G G G +G G G Sbjct: 965 KGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGE 1024 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 +G PG+ G +GS G G +G G KG GPPG G PG G +G GIAG GSPG+ Sbjct: 1025 KGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPG----IGIPGLRGEKGDQGIAGFPGSPGE 1080 Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPG 601 +G G G PG+ G PGL G PG G Sbjct: 1081 KGEKGSIGIPGMPGSPGLKGSPGSVG 1106 Score = 121 bits (303), Expect = 2e-27 Identities = 69/151 (45%), Positives = 80/151 (52%), Gaps = 10/151 (6%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514 + G PG PG +G KG +G+ G G G KG PGS+G G PG G G++G G Sbjct: 1071 IAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGY------PGSPGLPGEKGDKGLPG 1124 Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574 G PG+KG G GT GP G G KG+ PG +G PGS G G G PG G G PG Sbjct: 1125 LDGIPGVKGEAGLPGTPGPTGPAGQKGE---PGSDGIPGSAGEKGEPGLPG-RGFPGFPG 1180 Query: 575 QRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 +G G KGE G G G PG PG G Q F Sbjct: 1181 AKGDKGSKGEVGFPGLAGSPGIPGSKGEQGF 1211 Score = 119 bits (297), Expect = 1e-26 Identities = 80/202 (39%), Positives = 88/202 (43%), Gaps = 55/202 (27%) Query: 457 GAPGPPG------PRGFKGDMG---VKGPVGGRGPKGDPGSLGPLGPQG--PQGQPGEAG 505 G PGPPG P G KG+ G GP G GPKG PG G GP G GQ G G Sbjct: 326 GPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPG 385 Query: 506 PVGERGPVGPRGFPG--LKGSKGSFGTGGPRGQPGPKGDIG-----------PPGPEGPP 552 GERG G RGFPG L G G G GP G PGP G G PPG +GPP Sbjct: 386 FPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPP 445 Query: 553 G-------------------------------SPGPSGPQGKPGIAGKTGSPGQRGAMGP 581 G PGP GP G+ G G+ G+ G RG G Sbjct: 446 GIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGR 505 Query: 582 KGEPGIQGPPGLPGPPGPPGSQ 603 G G+ GP G PG G PG++ Sbjct: 506 DGVAGVPGPQGTPGLIGQPGAK 527 Score = 118 bits (296), Expect = 1e-26 Identities = 82/212 (38%), Positives = 91/212 (42%), Gaps = 70/212 (33%) Query: 457 GAPGPPGPRGFKGDMGVKGPVG---GRGPKGDPGSLGPLGPQGPQGQPGEAG-------- 505 G G GP+G KG+ G GP G G GP G+ G G G GP+G+PG G Sbjct: 311 GLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQP 370 Query: 506 -----PV----------GERGPVGPRGFPG--LKGSKGSFGTGGPRGQPGPKG------- 541 PV GERG G RGFPG L G G G GP G PGP G Sbjct: 371 GPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNG 430 Query: 542 ----DIGPPGPEGPPGSP----------------------------GPSGPQGKPGIAGK 569 GPPG +GPPG P GP GPQG P G+ Sbjct: 431 IVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPP---GE 487 Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G PGQ GA G +G PG G G+PGP G PG Sbjct: 488 IGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPG 519 Score = 118 bits (296), Expect = 1e-26 Identities = 73/171 (42%), Positives = 87/171 (50%), Gaps = 26/171 (15%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDP-------GSLGPLGPQGPQGQ---PGEAGP 506 G PG GP G G G G +G +G KG+ G GP GPQGP G+ PG+ G Sbjct: 437 GPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGA 496 Query: 507 VGERGPVGP---RGFPGLKGSKGSFGTGGPRGQPGP-------KGDIGPPGPEGPPGSPG 556 G+RG G G PG +G+ G G G +G+PG KGD G PG G PG G Sbjct: 497 KGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTG 556 Query: 557 PSGPQGK---PGIAGKTGSPGQRGAMGPKGEPGIQGPPGL---PGPPGPPG 601 +G G+ PG+ G GSPG G G +G PG G PG GPPGPPG Sbjct: 557 RAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPG 607 Score = 118 bits (295), Expect = 2e-26 Identities = 69/156 (44%), Positives = 79/156 (50%), Gaps = 16/156 (10%) Query: 459 PGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP-----------V 507 PGPPG G G G GP G RG G PG G G +G GQPG P Sbjct: 645 PGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLP 704 Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGP--KGDIGPPGPEGPPGSPGPSGPQGKPG 565 G+ GP G G PG G G+ G G +G+PG G G PG G PG+PG G G PG Sbjct: 705 GDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPG 764 Query: 566 IAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 + G+ G+ G G G +GEP GPPGLPG G PG Sbjct: 765 VPGEHGAIGPPGLQGIRGEP---GPPGLPGSVGSPG 797 Score = 116 bits (290), Expect = 7e-26 Identities = 67/157 (42%), Positives = 74/157 (47%), Gaps = 22/157 (14%) Query: 469 GDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSF 528 G G G +G +G PG G +G G QG G GP G++G G G PG KG++G Sbjct: 37 GKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPP 96 Query: 529 GTGGPRGQPGPKGDIGPPGPEGPPGSP---------GPSGPQGKPGIAGKTGSPGQRGAM 579 G G G PG G G GP GPPG P GP GP G PG AG G PG G Sbjct: 97 GASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMK 156 Query: 580 GP-------------KGEPGIQGPPGLPGPPGPPGSQ 603 G KGE G G PG PGPPG PG Q Sbjct: 157 GDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQ 193 Score = 98.2 bits (243), Expect = 2e-20 Identities = 53/119 (44%), Positives = 63/119 (52%), Gaps = 7/119 (5%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGP----KGDPGSLGPLGPQGPQGQPGEAGPVGER 510 L+G G G +G G G+ GP G GP KG+PG GP GP G +G G GP G++ Sbjct: 1324 LQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQ 1383 Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGP---PGPEGPPGSPGPSGPQGKPGI 566 G G G PG G G G G +G+ GP G GP PGP GP G PG GP G P + Sbjct: 1384 GVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSV 1442 Score = 95.9 bits (237), Expect = 1e-19 Identities = 52/110 (47%), Positives = 60/110 (54%), Gaps = 9/110 (8%) Query: 496 GPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP 555 G +GQ GE G G +G +G FPG++G +G P+G PG KGD G PG G G+ Sbjct: 43 GVKGQKGERGLPGLQGVIG---FPGMQGPEG------PQGPPGQKGDTGEPGLPGTKGTR 93 Query: 556 GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 GP G G PG G G PGQ G GP G PG G G GP GPPG F Sbjct: 94 GPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGF 143 Score = 82.0 bits (201), Expect = 1e-15 Identities = 46/102 (45%), Positives = 55/102 (53%), Gaps = 15/102 (14%) Query: 454 ILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPV 513 I++G PG PGP +G G+KG G GPKG G G +G GP G PG G G++G + Sbjct: 1354 IIKGEPGLPGP---EGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEM 1410 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP 555 GP G GPRG PGP G G PG GPPG+P Sbjct: 1411 GPA------------GPTGPRGFPGPPGPDGLPGSMGPPGTP 1440 Score = 58.2 bits (139), Expect = 2e-08 Identities = 32/72 (44%), Positives = 37/72 (51%), Gaps = 12/72 (16%) Query: 450 RNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509 + VT L G PGPPG GF G G K G +GP GP GP+G PG GP G Sbjct: 1383 QGVTGLVGIPGPPGIPGFDGAPGQK------------GEMGPAGPTGPRGFPGPPGPDGL 1430 Query: 510 RGPVGPRGFPGL 521 G +GP G P + Sbjct: 1431 PGSMGPPGTPSV 1442 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 151 bits (381), Expect = 2e-36 Identities = 81/158 (51%), Positives = 92/158 (58%), Gaps = 11/158 (6%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPL--------GPQGPQGQPGEAGP 506 L G PG PG G KG+ G G G +GP G PGS GP GPQGP G+PG G Sbjct: 1209 LPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGF 1268 Query: 507 VGERGPVGPRGFPG---LKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGK 563 G GP GP G PG +KG KG+ G G G PG KGD GPPG +G PG PG +G +G Sbjct: 1269 QGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGD 1328 Query: 564 PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 PG+ G G PG +G G G G +G PGL GPPGPPG Sbjct: 1329 PGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPG 1366 Score = 146 bits (368), Expect = 6e-35 Identities = 85/189 (44%), Positives = 97/189 (51%), Gaps = 40/189 (21%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLG------PLGPQGPQGQPGEAGP-- 506 L G PGPPG GFKG +G KG G GP G PG G P G GP GQPG GP Sbjct: 755 LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPG 814 Query: 507 ---VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKG-DI-GPPGPEGPPG---SPGPS 558 +G +GP GP G PG G G G G +G PGP G D+ GPPG G PG +PGP Sbjct: 815 LPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPI 874 Query: 559 GPQGKPGIAGKTGS------------------------PGQRGAMGPKGEPGIQGPPGLP 594 GP G PG+ GK G+ PG+ G G KG+ G+QG PGLP Sbjct: 875 GPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLP 934 Query: 595 GPPGPPGSQ 603 GP G GS+ Sbjct: 935 GPTGEKGSK 943 Score = 145 bits (367), Expect = 8e-35 Identities = 80/168 (47%), Positives = 91/168 (54%), Gaps = 20/168 (11%) Query: 455 LRGAPGP---PGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG 511 L G PGP PG G+ G+ G+KG VG G G PG+ G G G G PG GP G +G Sbjct: 1075 LPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKG 1134 Query: 512 PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS-----------GP 560 GP G PGL G G G GG GQPGP G+ G PG +G PG G GP Sbjct: 1135 ISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGP 1194 Query: 561 QGKPGIAGKTGS------PGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G PG++G+ G PG G GPKGEPG G PG+ GPPGPPGS Sbjct: 1195 PGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGS 1242 Score = 139 bits (350), Expect = 8e-33 Identities = 73/156 (46%), Positives = 88/156 (56%), Gaps = 8/156 (5%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP-- 512 + G PGPPGP G G GV G G G +G PG GP G +G +G+PG GP G P Sbjct: 900 MMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNL 959 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTG- 571 +G +G G G G G GP+G G GD G PG G PG PGP GP+G PG+ G+ G Sbjct: 960 LGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGL 1019 Query: 572 --SPGQRGAMGPKGEPG---IQGPPGLPGPPGPPGS 602 PG +G +G G PG ++GPPG G PG PGS Sbjct: 1020 IGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGS 1055 Score = 139 bits (349), Expect = 1e-32 Identities = 83/180 (46%), Positives = 95/180 (52%), Gaps = 35/180 (19%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRG---PKGDPGSLG---PLGPQGPQGQPGEA--GPVG 508 G PG PG G KGD G+ G G G PKG+PG G GP GP G PG A GP G Sbjct: 1193 GPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKG 1252 Query: 509 ERGPVGPRGFP---------------------GLKGSKGSFGTGGPRGQPGPKGDIGPPG 547 GP GP G P G+KG KG+ G G G PG KGD GPPG Sbjct: 1253 NPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPG 1312 Query: 548 PEGPPGSPGPSGPQGKPGIAGKTGSPGQR------GAMGPKGEPGIQGPPGLPGPPGPPG 601 +G PG PG +G +G PG+ G G PG + G+ GP+GEPG+ GPPG PG PGP G Sbjct: 1313 LQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSG 1372 Score = 138 bits (348), Expect = 1e-32 Identities = 82/173 (47%), Positives = 91/173 (52%), Gaps = 24/173 (13%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRG---PKGDPGSL--GPLGPQGPQGQPGEAGPVGERG 511 G PGPPG G G +G++GP G G PKG+PG GP GP G G G GP G+RG Sbjct: 719 GIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRG 778 Query: 512 ---PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG-----PEGPPGSPGPSGPQGK 563 P GP G GL G G G GP GQPGP G G PG P GPPG PGP G G Sbjct: 779 FPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGL 838 Query: 564 PGIAGKTGSPG-----------QRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 GI G+ G PG +RG+ G G PG GPPG PG PG G+ F Sbjct: 839 HGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGF 891 Score = 138 bits (347), Expect = 2e-32 Identities = 78/158 (49%), Positives = 88/158 (55%), Gaps = 18/158 (11%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPG------------SLGPLGPQGPQGQPGEA 504 G GPPGPRG KGD G+ GP G +G +G PG G G GPQG PG Sbjct: 66 GPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCN 125 Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564 G GERG G GFPGL+G G G G +G+PG PGP+G PG PGP G QG P Sbjct: 126 GTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLP 185 Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 G TG PG +GP G PG+ GPPG PG PGP G+ Sbjct: 186 G---PTGIPGP---IGPPGPPGLMGPPGPPGLPGPKGN 217 Score = 138 bits (347), Expect = 2e-32 Identities = 79/154 (51%), Positives = 84/154 (54%), Gaps = 11/154 (7%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVG--GRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 L G PG PG G G G KG G G G G PG G G GP G PG G +G GP Sbjct: 679 LPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGP 738 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572 GP GFPG KG G F GP G PG G G GP+G G PGP GP PG G G Sbjct: 739 PGPPGFPGPKGEPG-FALPGPPGPPGLPGFKGALGPKGDRGFPGPPGP---PGRTGLDGL 794 Query: 573 PGQRGAMGPKGEPGIQGPPGLP-----GPPGPPG 601 PG +G +GP G+PG GPPGLP GPPGPPG Sbjct: 795 PGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG 828 Score = 138 bits (347), Expect = 2e-32 Identities = 80/170 (47%), Positives = 88/170 (51%), Gaps = 22/170 (12%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGG------RGPKGDPGSLGPLG---PQGPQGQPGEAGPV 507 G PG PG G KGD G G G G KGDPG G G +GP G PG AGP Sbjct: 1294 GQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPE 1353 Query: 508 GERGPVGPRGFPGLKGSKGSF----GTGGP---------RGQPGPKGDIGPPGPEGPPGS 554 GE G +GP G PGL G G G GP +G PGP+G G PGP GPPG Sbjct: 1354 GEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGD 1413 Query: 555 PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQS 604 PG +G G G G+ G PG G G +G G GP GL GPPGPPG+ S Sbjct: 1414 PGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSS 1463 Score = 137 bits (345), Expect = 3e-32 Identities = 78/180 (43%), Positives = 92/180 (51%), Gaps = 31/180 (17%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP---------------------- 494 G PGPPG +G G G+ GP G +G G PG P P Sbjct: 1158 GQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPG 1217 Query: 495 -QGPQGQPGEAGPVGERGPVGPRGFPG--LKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP 551 GP+G+PG G G +GP GP G PG L+G KG+ G GP G+PGP G G PGPEGP Sbjct: 1218 LPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGP 1277 Query: 552 PGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPG------PPGPPGSQSF 605 PG PG G +G+ G G+ G PG G G +G PG+QG PG PG PG PG F Sbjct: 1278 PGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGF 1337 Score = 135 bits (340), Expect = 1e-31 Identities = 79/200 (39%), Positives = 92/200 (46%), Gaps = 54/200 (27%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP-----LGPQGPQGQPGEAGPVGER 510 RG PGPPGP G G G+ GP G GP G PG +GP +G QGP G PG GP+G+ Sbjct: 777 RGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQP 836 Query: 511 G-----------------------------------PVGPRGFPGLKGSKGSFGTGGPRG 535 G P+GP G PGL G G+ G G +G Sbjct: 837 GLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKG 896 Query: 536 QPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPP---- 591 + G G GPPGP G PG G G +G G+ G+ G PG G G KGEPG+ GPP Sbjct: 897 EMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD 956 Query: 592 ----------GLPGPPGPPG 601 G PG PG PG Sbjct: 957 PNLLGSKGEKGEPGLPGIPG 976 Score = 135 bits (340), Expect = 1e-31 Identities = 78/162 (48%), Positives = 89/162 (54%), Gaps = 16/162 (9%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPG--SLGPLGPQGPQGQPGEAGPVGE---R 510 +G GPPGP G G G G G +G KGDPG S+G G GP+G+PG G G + Sbjct: 1038 QGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIK 1097 Query: 511 GPVGPRGFPGLKGSKGSFGTGG------PRGQPGPKGDIGPPGPEGPPGSPGP---SGPQ 561 G VG G PGL G+ G+ G G G PGPKG GPPG G PG PGP G Sbjct: 1098 GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHP 1157 Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGL--PGPPGPPG 601 G+PG G+ G PGQ G GP G+ G G PG PGPPG PG Sbjct: 1158 GQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPG 1199 Score = 135 bits (339), Expect = 1e-31 Identities = 79/188 (42%), Positives = 93/188 (49%), Gaps = 43/188 (22%) Query: 457 GAPGPPGP--------RGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG 508 G PGPPGP +G KG+ G+ G G GPKG G G G G GQPG GP G Sbjct: 947 GLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPG 1006 Query: 509 ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP----------- 557 +G G G PGL G G GT G G PGP+G GPPGP G PG PG Sbjct: 1007 PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG 1066 Query: 558 ------------SGPQGKPGIAGKTGSPGQRGAM------------GPKGEPGIQGPPGL 593 GP+G+PG+ G G+PG +G++ G KG+PG+ G PG Sbjct: 1067 DPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGT 1126 Query: 594 PGPPGPPG 601 PGPPGP G Sbjct: 1127 PGPPGPKG 1134 Score = 135 bits (339), Expect = 1e-31 Identities = 74/149 (49%), Positives = 80/149 (53%), Gaps = 2/149 (1%) Query: 453 TILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512 T +G PGP GP G G+ G+KG G G G PG G G QGP G G G G G Sbjct: 1266 TGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGM 1325 Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572 G G PG+ G G G G G GP+G+ G GP GPPG PGPSG I G G Sbjct: 1326 KGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQ--SIIIKGDAGP 1383 Query: 573 PGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 PG G G KG PG QGP GLPGP GPPG Sbjct: 1384 PGIPGQPGLKGLPGPQGPQGLPGPTGPPG 1412 Score = 133 bits (335), Expect = 4e-31 Identities = 72/168 (42%), Positives = 87/168 (51%), Gaps = 23/168 (13%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGR----------GPKGDPGSLGPLGPQGPQGQPGEAGP 506 G PG PG +G +G+ GVKG G GP G PG G GP G G PG+ G Sbjct: 457 GPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGE 516 Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGP----------KGDIGPPGPEGPPGSPG 556 G+ G GP+G PG+ G+ G+ G G +G+PG KG++G PG G PG PG Sbjct: 517 KGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPG 576 Query: 557 PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP---GPPGPPG 601 G G PG+ G G PG G +G PG G PGLP GP GPPG Sbjct: 577 TPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG 624 Score = 133 bits (335), Expect = 4e-31 Identities = 80/178 (44%), Positives = 89/178 (50%), Gaps = 31/178 (17%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV------- 507 L G PGPPG GF G G KG G GPKG PG G G G G GE G + Sbjct: 498 LPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMK 557 Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGP---------KGDIGPPGPEGPPGSP--- 555 G++G +G G PGL G G+ G G G PGP KG+ GPPG G PG P Sbjct: 558 GDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNI 617 Query: 556 --------GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPG----IQGPPGLPGPPGPPG 601 GP GP G+ GI G G+PGQ G GPKG+PG G PGLPG PG G Sbjct: 618 GPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675 Score = 133 bits (335), Expect = 4e-31 Identities = 76/166 (45%), Positives = 85/166 (51%), Gaps = 19/166 (11%) Query: 453 TILRGAPGPPGPRGFKGDMGVKGP-----VGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV 507 T L G PGP G G G G GP +G +GP G PG GP+G G G PGE G Sbjct: 789 TGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDP 848 Query: 508 GE-----RGPVGPRGFPGLKGSKGSF---------GTGGPRGQPGPKGDIGPPGPEGPPG 553 G GP G RG PG+ G+ G G G G PG KG++G GP GPPG Sbjct: 849 GPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPG 908 Query: 554 SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGP 599 G G G PG+ G G GQ G GP GE G +G PGLPGPPGP Sbjct: 909 PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGP 954 Score = 133 bits (335), Expect = 4e-31 Identities = 77/168 (45%), Positives = 86/168 (51%), Gaps = 23/168 (13%) Query: 457 GAPGPPGPRGF---KGDMGVKGPVGGRGPKGDPGSLGP---LGPQGPQGQPGEAGPVGER 510 G PG G GF KG+MG+ GP G GP G PG G G G QGQPG GP GE+ Sbjct: 881 GLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEK 940 Query: 511 GPVGPRGFPG--------LKGSKGSF---------GTGGPRGQPGPKGDIGPPGPEGPPG 553 G G G PG L GSKG G GP+G G GD G PG G PG Sbjct: 941 GSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPG 1000 Query: 554 SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 PGP GP+G PG+ G+ G G G G G+ G GP G+ GPPGP G Sbjct: 1001 LPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSG 1048 Score = 132 bits (332), Expect = 9e-31 Identities = 76/170 (44%), Positives = 88/170 (51%), Gaps = 25/170 (14%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGP--------QGQPGEAGPVG 508 G PG G G +G G+ GP G +G KG+PG GP GP P +G+PG G G Sbjct: 917 GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPG 976 Query: 509 ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD---------IGPPGPEGP------PG 553 GP G +G PG G G G G G PGPKG+ IGPPG +G PG Sbjct: 977 VSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG 1036 Query: 554 SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQ--GPPGLPGPPGPPG 601 G GP G G+ G+ GSPG G G KG+PGI G PGLPGP G PG Sbjct: 1037 PQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPG 1086 Score = 130 bits (326), Expect = 5e-30 Identities = 75/163 (46%), Positives = 88/163 (53%), Gaps = 20/163 (12%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 GAPGP GP G G G G G G KG+ G +GP GP GP G PG +G G +G G + Sbjct: 869 GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ 928 Query: 517 GFPGLKGSKGSFGTGGPRGQPGP-----------KGDIGPPGPEGPPGSPGPSGPQG--- 562 G PGL G G G+ G G PGP KG+ G PG G PG GP G QG Sbjct: 929 GQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPG 988 Query: 563 ---KPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602 +PG++G+ G P G GPKG PG+ G PGL GPPG G+ Sbjct: 989 DPGQPGLSGQPGLP---GPPGPKGNPGLPGQPGLIGPPGLKGT 1028 Score = 129 bits (324), Expect = 8e-30 Identities = 74/151 (49%), Positives = 80/151 (52%), Gaps = 11/151 (7%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G PGP G +G +G G G G GPKGDPG G+PG G G G VG Sbjct: 626 GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTIT-----QPGKPGLPGNPGRDGDVGLP 680 Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGD--IGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574 G PGL G G G G +G+PG G GPPGP+G PG PGP G G PG G G PG Sbjct: 681 GDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPG 740 Query: 575 QRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 G GPKGEPG LPGPPGPPG F Sbjct: 741 PPGFPGPKGEPGF----ALPGPPGPPGLPGF 767 Score = 129 bits (323), Expect = 1e-29 Identities = 74/151 (49%), Positives = 78/151 (51%), Gaps = 9/151 (5%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516 G G G RGF G G G G GP+G PG P G +G G PG GP G RGP G Sbjct: 42 GIKGEKGERGFPGLEGHPGLPGFPGPEGPPG---PRGQKGDDGIPGPPGPKGIRGPPGLP 98 Query: 517 GFPG---LKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573 GFPG L G G G GP+G PG G G G G PG PG GP G PGI G G P Sbjct: 99 GFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEP 158 Query: 574 GQ---RGAMGPKGEPGIQGPPGLPGPPGPPG 601 G GPKG PG GPPG+ G PGP G Sbjct: 159 GSIIMSSLPGPKGNPGYPGPPGIQGLPGPTG 189 Score = 126 bits (317), Expect = 5e-29 Identities = 75/163 (46%), Positives = 82/163 (50%), Gaps = 27/163 (16%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 +G PG PGP G +G + GP G GP G PG G +GP GP G PG G +G Sbjct: 170 KGNPGYPGPPGIQG---LPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMG------- 219 Query: 516 RGFPGLKGSKGSFGTGGPRGQPG-------------PKGDIGPPGPEGPPGSPGPSGPQG 562 F G KG KG G GP G PG KGD G PG GPPG PG GP G Sbjct: 220 LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPG 279 Query: 563 KP----GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 P G G+ G PG+RG G GE G G PGLPG PG PG Sbjct: 280 PPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPG 322 Score = 126 bits (316), Expect = 7e-29 Identities = 84/222 (37%), Positives = 103/222 (46%), Gaps = 52/222 (23%) Query: 434 IVEEMKAVDTQHGEILRNVTILRGAPGPPG-------PRGFKGDMGVKGPVGGRGPKG-- 484 I E+ + +D + + + + RG PGPPG P G KG+ G +G G RG G Sbjct: 244 ISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD 303 Query: 485 -------------DPGSLGPLGPQGPQGQPGEAGP----------------VGERGPVGP 515 DPG G G G +GQ G+ GP +GE+G +G Sbjct: 304 GENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGL 363 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGD--IGPPGPEGPPGSPGPSGPQGKPGIA--GKTG 571 G PG KG +G G GP G PGP G +GPPGP G PG G G +G PGI+ G G Sbjct: 364 PGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPG 423 Query: 572 SPGQRGAMGPKGEPGIQGP----------PGLPGPPGPPGSQ 603 GQ GA G G PG GP PG PGPPG PG + Sbjct: 424 LDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDK 465 Score = 125 bits (315), Expect = 9e-29 Identities = 70/149 (46%), Positives = 82/149 (55%), Gaps = 3/149 (2%) Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515 RG PG G G G G +GP G RG KGD G GP GP+G +G PG G G G G Sbjct: 50 RGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGM 109 Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575 G G G +G G G +G+ G G G PG +GPPG PG G +G+PG + PG Sbjct: 110 PGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGP 169 Query: 576 RGAMGPKGEPGIQ---GPPGLPGPPGPPG 601 +G G G PGIQ GP G+PGP GPPG Sbjct: 170 KGNPGYPGPPGIQGLPGPTGIPGPIGPPG 198 Score = 125 bits (315), Expect = 9e-29 Identities = 86/216 (39%), Positives = 96/216 (44%), Gaps = 65/216 (30%) Query: 453 TILRGAPGPPGPRGF---KGDMGVKGPVGG-----RGPKGDPGSLGPLGPQGPQGQ---- 500 T + G GPPGP G G G+ GP G +GPKG+ G G GP GP GQ Sbjct: 188 TGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQ 247 Query: 501 ---------------PGEAGPVGE---RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD 542 PG+ GP G RGP GP G G KG KG G G RG+PG G+ Sbjct: 248 KRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGE 305 Query: 543 IGPPGPEGPPGSP---------------GPSGPQGKPGIA-------------GKTGSPG 574 G PG G PG P G +GP G PG+ G G PG Sbjct: 306 NGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPG 365 Query: 575 QRGAMGPKGEPGIQGPPGLPGPP-----GPPGSQSF 605 G G +G PGIQGPPGLPGPP GPPG F Sbjct: 366 LPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGF 401 Score = 125 bits (313), Expect = 1e-28 Identities = 83/204 (40%), Positives = 95/204 (46%), Gaps = 55/204 (26%) Query: 457 GAPGPPG---PR-------GFKGDMGVKGPVGGRGPKGDPGSLGP-----------LGPQ 495 G PGPPG PR G KG++G+ G G +G +G PG GP +GP Sbjct: 337 GPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPP 396 Query: 496 GPQGQPGEAGPVGERGPVGPR--GFPGLKGSKGSFGTGGPRGQPGP----KGDIGPPGPE 549 GP G PGE G G+ GP G G PGL G G+ G GP G GP +I PGP Sbjct: 397 GPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPP 456 Query: 550 GPPGSPGP-------------------------SGPQGKPGIAGKTGSPGQRGAMGPKGE 584 GPPGSPG SGP G+PG+ G G PG G G KGE Sbjct: 457 GPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGE 516 Query: 585 PG---IQGPPGLPGPPGPPGSQSF 605 G GP GLPG PG PG+ F Sbjct: 517 KGQAGATGPKGLPGIPGAPGAPGF 540 Score = 124 bits (310), Expect = 3e-28 Identities = 71/148 (47%), Positives = 79/148 (53%), Gaps = 3/148 (2%) Query: 459 PGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGF 518 PGPPGP G GD G++G G +G KGD +G G G PG+ G G GP G GF Sbjct: 453 PGPPGPPGSPGDKGLQGEQGVKGDKGDT-CFNCIGT-GISGPPGQPGLPGLPGPPGSLGF 510 Query: 519 PGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGP-QGKPGIAGKTGSPGQRG 577 PG KG KG G GP+G PG G G PG G G PG G G G+ GSPG G Sbjct: 511 PGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPG 570 Query: 578 AMGPKGEPGIQGPPGLPGPPGPPGSQSF 605 G G PG G PGLPGP G PG +F Sbjct: 571 LPGLPGTPGQDGLPGLPGPKGEPGGITF 598 Score = 123 bits (309), Expect = 4e-28 Identities = 76/177 (42%), Positives = 85/177 (48%), Gaps = 33/177 (18%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQP---GEAGPVGERGPV 513 G G PGP+G G G KG RG G PG G GP GP G P GE G + Sbjct: 111 GHDGAPGPQGIPGCNGTKGE---RGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLP 167 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPP---GPEGPPGSPGP--------SGPQG 562 GP+G PG G G G GP G PGP G GPP GP GPPG PGP GP+G Sbjct: 168 GPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKG 227 Query: 563 KPGIAGKTGSPG----------------QRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603 + G G G PG Q+G G G+ G GPPG+ GPPGPPG + Sbjct: 228 EKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGE 284 Score = 123 bits (309), Expect = 4e-28 Identities = 74/170 (43%), Positives = 83/170 (48%), Gaps = 28/170 (16%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE--AGPVGERGPVG 514 G PGPPG +G G G+ GP+G GP G G GP G GP+G G GP GE+G G Sbjct: 174 GYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQG 233 Query: 515 PRGFPGLKGS-------------KGSFGTGGPRGQPGPKGDIGPPGP----------EGP 551 +G PG G KG G G RG PGP G GPPGP +G Sbjct: 234 LQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGE 293 Query: 552 PGS---PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPG 598 PG PG G G+PGI G G PG G G GE G +G G PGPPG Sbjct: 294 PGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPG 343 Score = 103 bits (258), Expect = 4e-22 Identities = 61/130 (46%), Positives = 64/130 (49%), Gaps = 27/130 (20%) Query: 499 GQPGEAGPV------------GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGP---KGDI 543 GQP EA G +G G RGFPGL+G G G GP G PGP KGD Sbjct: 21 GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80 Query: 544 GPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGP------------P 591 G PGP GP G GP G G PG G G PG GA GP+G PG G P Sbjct: 81 GIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP 140 Query: 592 GLPGPPGPPG 601 GL GPPGPPG Sbjct: 141 GLQGPPGPPG 150 Score = 78.2 bits (191), Expect = 2e-14 Identities = 45/106 (42%), Positives = 52/106 (49%), Gaps = 21/106 (19%) Query: 454 ILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPV 513 I++G GPPG G G G+ GP QGPQG PG GP G+ Sbjct: 1376 IIKGDAGPPGIPGQPGLKGLPGP------------------QGPQGLPGPTGPPGD---P 1414 Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSG 559 G G PG G+ G G G GQPG +G GPPGP+G G PGP G Sbjct: 1415 GRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460 Score = 59.7 bits (143), Expect = 8e-09 Identities = 33/71 (46%), Positives = 37/71 (52%), Gaps = 12/71 (16%) Query: 535 GQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP 594 G G KG+ G PG EG PG PG GP+G PG G+ KG+ GI GPPG Sbjct: 42 GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQ------------KGDDGIPGPPGPK 89 Query: 595 GPPGPPGSQSF 605 G GPPG F Sbjct: 90 GIRGPPGLPGF 100 >gi|145701009 acetylcholinesterase collagen-like tail subunit isoform III precursor [Homo sapiens] Length = 421 Score = 150 bits (380), Expect = 2e-36 Identities = 77/154 (50%), Positives = 97/154 (62%), Gaps = 12/154 (7%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLG---PQGPQGQPGEAGPVG---ER 510 G PG GP+G KG++G G G GP G PG GP+G P+GP+G+ G+ G +G R Sbjct: 77 GLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSR 136 Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA--- 567 GP+G +G+PG +G KGS G +G GPKG+ G PG G G G GP+G+PGIA Sbjct: 137 GPMGSKGYPGSRGEKGS---RGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHR 193 Query: 568 GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601 G TG PG+RG G KG+ G+ GPPG PGP G PG Sbjct: 194 GPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPG 227 Score = 136 bits (342), Expect = 6e-32 Identities = 75/154 (48%), Positives = 89/154 (57%), Gaps = 19/154 (12%) Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGP------------KGDPGSLGPLGPQGPQGQPGEA 504 G PGP GPRG KGD+G+ G G RGP KG G G LGP+G +G PG Sbjct: 113 GWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFP 172 Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564 G +G++G +GP+G PG+ G +G G G RG+ G KGD G GPPG PGPSG G+P Sbjct: 173 GMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGD---SGVMGPPGKPGPSGQPGRP 229 Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPG--LPGP 596 G G P + MGPKGE G GPPG L GP Sbjct: 230 GPPGP--PPAGQLIMGPKGERGFPGPPGRCLCGP 261 Score = 90.1 bits (222), Expect = 5e-18 Identities = 55/121 (45%), Positives = 63/121 (52%), Gaps = 28/121 (23%) Query: 508 GERGPVGPRGFPGL---KGSKGSFGTGGPRGQPGP------KGDIGPPGPEGP------- 551 G R P GP G PG KG KG G G +G+PGP G IG PGPEGP Sbjct: 69 GGRSP-GPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDL 127 Query: 552 -----PGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGL------PGPPGPP 600 PGS GP G +G PG G+ GS G++G +GPKGE G G PG+ GP G P Sbjct: 128 GMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEP 187 Query: 601 G 601 G Sbjct: 188 G 188 Score = 67.8 bits (164), Expect = 3e-11 Identities = 35/78 (44%), Positives = 40/78 (51%) Query: 528 FGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGI 587 F G G PG G GP G +G G PG G G PG+ G G G G GP+GE G Sbjct: 67 FRGGRSPGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGD 126 Query: 588 QGPPGLPGPPGPPGSQSF 605 G GLPG GP GS+ + Sbjct: 127 LGMMGLPGSRGPMGSKGY 144 Score = 55.1 bits (131), Expect = 2e-07 Identities = 32/71 (45%), Positives = 35/71 (49%), Gaps = 6/71 (8%) Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE--RGP 512 + G GP G G +G G KG G GP G PG G G GP G P P G+ GP Sbjct: 189 IAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP----PAGQLIMGP 244 Query: 513 VGPRGFPGLKG 523 G RGFPG G Sbjct: 245 KGERGFPGPPG 255 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.136 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,102,392 Number of Sequences: 37866 Number of extensions: 1949947 Number of successful extensions: 65679 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 400 Number of HSP's successfully gapped in prelim test: 1079 Number of HSP's that attempted gapping in prelim test: 10338 Number of HSP's gapped (non-prelim): 13260 length of query: 606 length of database: 18,247,518 effective HSP length: 108 effective length of query: 498 effective length of database: 14,157,990 effective search space: 7050679020 effective search space used: 7050679020 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.