Guide to the Human Genome
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Search of human proteins with 33598924

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33598924 scavenger receptor class A, member 3 isoform 1
[Homo sapiens]
         (606 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33598924 scavenger receptor class A, member 3 isoform 1 [Homo...  1229   0.0  
gi|33598922 scavenger receptor class A, member 3 isoform 2 [Homo...   900   0.0  
gi|18641360 collectin sub-family member 12 [Homo sapiens]             351   1e-96
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      159   9e-39
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     158   1e-38
gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]       157   2e-38
gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]       157   2e-38
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     157   3e-38
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   157   3e-38
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   157   3e-38
gi|119508426 alpha 3 type IX collagen [Homo sapiens]                  157   3e-38
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...   156   5e-38
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...   156   5e-38
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...   156   5e-38
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]   156   6e-38
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   155   1e-37
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   155   1e-37
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   155   1e-37
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]      155   1e-37
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...   154   3e-37
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...   154   3e-37
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...   154   3e-37
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...   154   3e-37
gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens]              154   3e-37
gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens]        153   4e-37
gi|48762934 alpha 2 type I collagen [Homo sapiens]                    153   5e-37
gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]              152   7e-37
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]    152   9e-37
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   151   2e-36
gi|145701009 acetylcholinesterase collagen-like tail subunit iso...   150   2e-36

>gi|33598924 scavenger receptor class A, member 3 isoform 1 [Homo
           sapiens]
          Length = 606

 Score = 1229 bits (3181), Expect = 0.0
 Identities = 606/606 (100%), Positives = 606/606 (100%)

Query: 1   MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKGRPGPRCSRCQKNLSLHTSVRILYL 60
           MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKGRPGPRCSRCQKNLSLHTSVRILYL
Sbjct: 1   MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKGRPGPRCSRCQKNLSLHTSVRILYL 60

Query: 61  FLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGLDPKALNNCSFCH 120
           FLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGLDPKALNNCSFCH
Sbjct: 61  FLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGLDPKALNNCSFCH 120

Query: 121 EAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQ 180
           EAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQ
Sbjct: 121 EAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQ 180

Query: 181 VNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRK 240
           VNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRK
Sbjct: 181 VNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRK 240

Query: 241 TDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDL 300
           TDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDL
Sbjct: 241 TDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDL 300

Query: 301 VLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTI 360
           VLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTI
Sbjct: 301 VLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTI 360

Query: 361 FTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLL 420
           FTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLL
Sbjct: 361 FTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLL 420

Query: 421 SARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGR 480
           SARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGR
Sbjct: 421 SARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGR 480

Query: 481 GPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPK 540
           GPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPK
Sbjct: 481 GPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPK 540

Query: 541 GDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPP 600
           GDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPP
Sbjct: 541 GDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPP 600

Query: 601 GSQSFY 606
           GSQSFY
Sbjct: 601 GSQSFY 606


>gi|33598922 scavenger receptor class A, member 3 isoform 2 [Homo
           sapiens]
          Length = 466

 Score =  900 bits (2326), Expect = 0.0
 Identities = 457/457 (100%), Positives = 457/457 (100%)

Query: 1   MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKGRPGPRCSRCQKNLSLHTSVRILYL 60
           MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKGRPGPRCSRCQKNLSLHTSVRILYL
Sbjct: 1   MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKGRPGPRCSRCQKNLSLHTSVRILYL 60

Query: 61  FLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGLDPKALNNCSFCH 120
           FLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGLDPKALNNCSFCH
Sbjct: 61  FLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGLDPKALNNCSFCH 120

Query: 121 EAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQ 180
           EAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQ
Sbjct: 121 EAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQ 180

Query: 181 VNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRK 240
           VNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRK
Sbjct: 181 VNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRK 240

Query: 241 TDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDL 300
           TDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDL
Sbjct: 241 TDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDL 300

Query: 301 VLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTI 360
           VLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTI
Sbjct: 301 VLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTI 360

Query: 361 FTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLL 420
           FTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLL
Sbjct: 361 FTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLL 420

Query: 421 SARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRG 457
           SARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRG
Sbjct: 421 SARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRG 457


>gi|18641360 collectin sub-family member 12 [Homo sapiens]
          Length = 742

 Score =  351 bits (901), Expect = 1e-96
 Identities = 203/587 (34%), Positives = 324/587 (55%), Gaps = 2/587 (0%)

Query: 18  EDLAGDDEDMPTFPCTQKG-RPGPRCSRCQKNLSLHTSVRILYLFLALLLVAVAVLASLV 76
           +D   ++E++ +F   + G + G +C++C+ N +L  S+ +LY+  ALL + VA+L   V
Sbjct: 2   KDDFAEEEEVQSFGYKRFGIQEGTQCTKCKNNWALKFSIILLYILCALLTITVAILGYKV 61

Query: 77  FRKVDSLSEDISLTQSIYDKKLVLMQKNLQGL-DPKALNNCSFCHEAGQLGPEIRKLQEE 135
             K+D+++  +  ++  YD KL  ++ +L+ L D       S   E      +I  L+++
Sbjct: 62  VEKMDNVTGGMETSRQTYDDKLTAVESDLKKLGDQTGKKAISTNSELSTFRSDILDLRQQ 121

Query: 136 LEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQVNQSLGLFLAQVRGW 195
           L  I +     +  L++   + + L     Q+ + + + SF I  VN++L  +   V   
Sbjct: 122 LREITEKTSKNKDTLEKLQASGDALVDRQSQLKETLENNSFLITTVNKTLQAYNGYVTNL 181

Query: 196 QATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRKTDEETLTLQKIVTDW 255
           Q  T+ L  +L++       V   ++ +N T  Q    I  +QR  D+ +  +Q+I  D+
Sbjct: 182 QQDTSVLQGNLQNQMYSHNVVIMNLNNLNLTQVQQRNLITNLQRSVDDTSQAIQRIKNDF 241

Query: 256 QNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDLVLQVMGLQLQLDNIS 315
           QN  ++F   +  +    E V+++Q     +S     N++++ D+  Q+     Q++NI+
Sbjct: 242 QNLQQVFLQAKKDTDWLKEKVQSLQTLAANNSALAKANNDTLEDMNSQLNSFTGQMENIT 301

Query: 316 SFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTIFTNINATDNHVHSML 375
           +    +E+N+ DLQ     A+NRT  +F  LE R    E +I  I +NI+ T +H+ ++ 
Sbjct: 302 TISQANEQNLKDLQDLHKDAENRTAIKFNQLEERFQLFETDIVNIISNISYTAHHLRTLT 361

Query: 376 KYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLLSARLDLNVRNLSMIV 435
             L++VR +CT     H ++L  LN +++ +   +  LR +  L+ +RLD  V NLS+I+
Sbjct: 362 SNLNEVRTTCTDTLTKHTDDLTSLNNTLANIRLDSVSLRMQQDLMRSRLDTEVANLSVIM 421

Query: 436 EEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQ 495
           EEMK VD++HG++++N TIL+G PGP GPRG +G  G  GP G +G KG+ G  GP GP 
Sbjct: 422 EEMKLVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPA 481

Query: 496 GPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP 555
           G +G  G AGP GERG  G +G  G KGS+GS G  GP+G  G  G  GPPG EG PG  
Sbjct: 482 GERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQ 541

Query: 556 GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           GP G QG  G  G+ G PG RG  G  G PG+ GP G PGPPGP G+
Sbjct: 542 GPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 25/53 (47%), Positives = 25/53 (47%), Gaps = 3/53 (5%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509
           G PG PGPRG  G  GV G  G   PKG PG  GP G   P     E  P  E
Sbjct: 554 GEPGVPGPRGLPGLPGVPGMPG---PKGPPGPPGPSGAVVPLALQNEPTPAPE 603


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  159 bits (401), Expect = 9e-39
 Identities = 81/164 (49%), Positives = 94/164 (57%), Gaps = 15/164 (9%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            L+G PGPPG +G  GD+G  GP G  GP+G  G+ G  GPQGP G  G  G VGE+G  G
Sbjct: 1229 LQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPG 1288

Query: 515  PRGFPGL---------KGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP------SG 559
              G PGL         KG +G  G  GP G  GP G  GPPG +GP GSPGP       G
Sbjct: 1289 EAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPG 1348

Query: 560  PQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            P G+PG AG+ G PG +G  G  G+ G  GP G PGP GPPG +
Sbjct: 1349 PPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKR 1392



 Score =  158 bits (400), Expect = 1e-38
 Identities = 84/167 (50%), Positives = 95/167 (56%), Gaps = 18/167 (10%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQ---PGEAGP----- 506
            L+G  GPPGP G  G  G +GP G  GP G PG  GP GP GP G+   PGE GP     
Sbjct: 1073 LKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAG 1132

Query: 507  -------VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP---EGPPGSPG 556
                   VG  GP GP G PG  G KG  G  G +G  G KG+ GPPGP   +GP G PG
Sbjct: 1133 RDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPG 1192

Query: 557  PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            PSG  G+PG  G+ G  GQ+G  GP+G PG  GP GL G PGPPG +
Sbjct: 1193 PSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEK 1239



 Score =  157 bits (397), Expect = 3e-38
 Identities = 81/157 (51%), Positives = 89/157 (56%), Gaps = 12/157 (7%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP---- 512
            G  GPPG  G KG++G  G  G +G KG+ G  GP GPQGP GQPG +G  GE GP    
Sbjct: 1147 GPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQ 1206

Query: 513  --------VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564
                     GPRGFPG  G  G  G  GP G+ G  GD+G  GP GPPG  GPSG  G  
Sbjct: 1207 GLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGAD 1266

Query: 565  GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  G  G  G  GA+G KGEPG  G PGLPG  GPPG
Sbjct: 1267 GPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPG 1303



 Score =  157 bits (396), Expect = 3e-38
 Identities = 79/146 (54%), Positives = 88/146 (60%), Gaps = 3/146 (2%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            RG PGP GP G +G+ G KG  G  GP   PG  GP+GPQG  G+PG  G  G  GPVG 
Sbjct: 1392 RGPPGPAGPEGRQGEKGAKGEAGLEGP---PGKTGPIGPQGAPGKPGPDGLRGIPGPVGE 1448

Query: 516  RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
            +G PG  G  G  G  GP G PG KGD GP G +G PG  G  GP G+ G  G  G PG 
Sbjct: 1449 QGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP 1508

Query: 576  RGAMGPKGEPGIQGPPGLPGPPGPPG 601
            +G+ GPKGE GI GP G  GPPGPPG
Sbjct: 1509 QGSSGPKGEQGITGPSGPIGPPGPPG 1534



 Score =  156 bits (395), Expect = 5e-38
 Identities = 84/173 (48%), Positives = 95/173 (54%), Gaps = 24/173 (13%)

Query: 450  RNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509
            R  T  +G  GPPGP G    +G +GP G  GP G+ G  GP GP G QG PG AG  G 
Sbjct: 981  RGETGFQGKTGPPGPPGV---VGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGT 1037

Query: 510  RGPVGPRGFPGLKGSKGSFGTGGPRGQPGP------KGDIGPPGPEGPPGSPGP------ 557
            +G  GP G PG  G  G  G  G RG PGP      KG+ GPPGP GP GSPG       
Sbjct: 1038 KGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGA 1097

Query: 558  ---------SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
                      GPQG PG AG+ G+PG++G  GP G  G+QGP GLPGP GP G
Sbjct: 1098 AGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVG 1150



 Score =  155 bits (392), Expect = 1e-37
 Identities = 81/153 (52%), Positives = 89/153 (58%), Gaps = 9/153 (5%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G PGP G RG KG+ G  G  G  GPKG PG  GP G  GP G PG+ GP GE GP G  
Sbjct: 1300 GPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQD 1359

Query: 517  GFPGLKGSKGS---FGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI---AGKT 570
            G PG KG  G     G+ GP G+PGP G   PPG  GPPG  GP G QG+ G    AG  
Sbjct: 1360 GPPGDKGDDGEPGQTGSPGPTGEPGPSG---PPGKRGPPGPAGPEGRQGEKGAKGEAGLE 1416

Query: 571  GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G PG+ G +GP+G PG  GP GL G PGP G Q
Sbjct: 1417 GPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQ 1449



 Score =  155 bits (391), Expect = 1e-37
 Identities = 84/185 (45%), Positives = 93/185 (50%), Gaps = 36/185 (19%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGG------------RGPKGDPGSLGPLGPQGPQGQPG 502
            L G  GPPG RGF GD G+ GPVG              GP G PG  GP G  GP G PG
Sbjct: 1046 LPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPG 1105

Query: 503  EAGPVGERGPVGPRGFPGLKGSKGSFGTG---GPRGQPGPKGDIGPP------------- 546
              GP G  GP G +G PG KG +G  G     GP G PGP G +GPP             
Sbjct: 1106 RPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPG 1165

Query: 547  --------GPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPG 598
                    G +GPPG  GP GP G+PG +G  G PG RG  G  G+ G +GP G PGPPG
Sbjct: 1166 QKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPG 1225

Query: 599  PPGSQ 603
            P G Q
Sbjct: 1226 PVGLQ 1230



 Score =  150 bits (380), Expect = 2e-36
 Identities = 82/165 (49%), Positives = 89/165 (53%), Gaps = 21/165 (12%)

Query: 460 GPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP---R 516
           GP GP G  G  G  GP G  G KG+PG +GP GP+G QG PG AG  G RG  G    R
Sbjct: 559 GPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGAR 618

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ- 575
           G PG  G KG  G  G  G PG KG  G PGP GPPG PG  G +G  G  G  G PG+ 
Sbjct: 619 GMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEP 678

Query: 576 --RGAMGPKGEPGIQGPPGL------PGP---------PGPPGSQ 603
             RG +GPKG PG  GPPG+      PGP         PGPPG Q
Sbjct: 679 GPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQ 723



 Score =  150 bits (380), Expect = 2e-36
 Identities = 81/182 (44%), Positives = 96/182 (52%), Gaps = 36/182 (19%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLG------------------PLGPQGPQ 498
            G PGPPGPRG  G  G  GP G  G  G+PG++G                  P GP+G +
Sbjct: 1249 GPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGER 1308

Query: 499  GQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS---- 554
            G+ GE+GP G  GP GP+G PG  G KGS G  G  G PGP G+ GP G +GPPG     
Sbjct: 1309 GEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDD 1368

Query: 555  --------------PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPP 600
                          PGPSGP GK G  G  G  G++G  G KGE G++GPPG  GP GP 
Sbjct: 1369 GEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQ 1428

Query: 601  GS 602
            G+
Sbjct: 1429 GA 1430



 Score =  149 bits (375), Expect = 9e-36
 Identities = 76/149 (51%), Positives = 86/149 (57%), Gaps = 6/149 (4%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           RG  GPPGPR   G+ G +GP G  GP GDPG LGP G +G  G PG  G  G +GP G 
Sbjct: 828 RGEIGPPGPR---GEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGS 884

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP---EGPPGSPGPSGPQGKPGIAGKTGS 572
            GFPG  G+ G  G  G  G+PGP+G  GP GP    GP G  G  GP+G  G  G  G 
Sbjct: 885 IGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGP 944

Query: 573 PGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           PG+RG  GP+G  G  GP G PGPPG  G
Sbjct: 945 PGERGPNGPQGPTGFPGPKGPPGPPGKDG 973



 Score =  148 bits (374), Expect = 1e-35
 Identities = 79/166 (47%), Positives = 91/166 (54%), Gaps = 18/166 (10%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQG------------PQGQPGE 503
           RG PG  GP+G +G  G+ G  G +G +GDPG  GP GP G            P+G PGE
Sbjct: 618 RGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGE 677

Query: 504 AGPVGERGPVGPRGFPG------LKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP 557
            GP G  GP GP G PG      + G  G  G  GP+G+PGP G  G PG +G PG  G 
Sbjct: 678 PGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGA 737

Query: 558 SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            GP G+ G  GK G PG  GA GP G PG +GPPG  G  GPPG Q
Sbjct: 738 IGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQ 783



 Score =  148 bits (374), Expect = 1e-35
 Identities = 83/180 (46%), Positives = 91/180 (50%), Gaps = 33/180 (18%)

Query: 456  RGAPGPPGPRGFKGDMGV------KGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509
            RG  GP GPRG +G  G+      KG  GG GP G PG  GP GPQGP G PG  GP G 
Sbjct: 909  RGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGP 968

Query: 510  RGPVGPRGFPGLKGSKGSFGTGGPRGQP------GPKGDIGPPGPEGPPGSPGPSGPQGK 563
             G  G  G PG +G  G  G  GP G P      GP G+ GP G  G PG PGP G QG 
Sbjct: 969  PGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGL 1028

Query: 564  PGIAGKTGS---------------------PGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
            PG+AGK G+                     PG RG  GP G  G++G  G PGPPGP GS
Sbjct: 1029 PGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGS 1088



 Score =  147 bits (372), Expect = 2e-35
 Identities = 87/174 (50%), Positives = 97/174 (55%), Gaps = 27/174 (15%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVG--GR-GPKGD---PGSLGPLGPQGPQGQPGEAGPVGER 510
            G PGP GP G KG +GV G  G  GR GPKG    PG  G  G +G +G PG+ GP G+R
Sbjct: 853  GDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQR 912

Query: 511  GPVGPRGF---------PGLKGSKGSFGTGGPRGQPGPKGDIGP---PGPEGPPGSPGPS 558
            GP GPRG          PG KG+ G  G  GP G+ GP G  GP   PGP+GPPG PG  
Sbjct: 913  GPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKD 972

Query: 559  GPQGKPG------IAGKTGSPGQRGAMGPKGEPGIQGPPGL---PGPPGPPGSQ 603
            G  G PG        GKTG PG  G +GP+G  G  GP G    PGPPGPPG Q
Sbjct: 973  GLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQ 1026



 Score =  147 bits (371), Expect = 3e-35
 Identities = 76/152 (50%), Positives = 90/152 (59%), Gaps = 6/152 (3%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG---PVGERGP 512
           +G PGPPGP G  G  G  GP G  GP+G+PG  G  G  G QG PG  G   P GE+GP
Sbjct: 687 KGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGP 746

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572
           +G  G PG+ G+ G  G  G  G PG KG  GPPGP+GP G PGP G +G  GI G  G+
Sbjct: 747 LGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGT 806

Query: 573 PGQRGA---MGPKGEPGIQGPPGLPGPPGPPG 601
            G++G     G KG+ GI+G  G  GPPGP G
Sbjct: 807 KGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRG 838



 Score =  145 bits (365), Expect = 1e-34
 Identities = 78/161 (48%), Positives = 83/161 (51%), Gaps = 15/161 (9%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            RG  G  GP G  G  G KGP G  GPKG PG +G  G  GP G+PG AG  G  G  G 
Sbjct: 1308 RGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGD 1367

Query: 516  RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP---------------EGPPGSPGPSGP 560
             G PG  GS G  G  GP G PG +G  GP GP               EGPPG  GP GP
Sbjct: 1368 DGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGP 1427

Query: 561  QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            QG PG  G  G  G  G +G +G PG  GP G PGP GPPG
Sbjct: 1428 QGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPG 1468



 Score =  144 bits (362), Expect = 3e-34
 Identities = 83/167 (49%), Positives = 88/167 (52%), Gaps = 24/167 (14%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGPVG- 508
            RG  G  GP G  G  G +GP G  G KG PG  GP GP      QGP G PG AGPVG 
Sbjct: 1092 RGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGP 1151

Query: 509  --ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566
              E G  G  G PG KGSKG  G  GP G  GP+G IG PGP G  G PGP G Q   G+
Sbjct: 1152 PGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQ---GL 1208

Query: 567  AGKTGSPGQRGAMGPKGEPGIQGPPGLP------------GPPGPPG 601
             G+ G  G RG  GP G  G+QG PG P            GPPGPPG
Sbjct: 1209 FGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPG 1255



 Score =  144 bits (362), Expect = 3e-34
 Identities = 77/164 (46%), Positives = 89/164 (54%), Gaps = 18/164 (10%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            +G PGP G +G  G+ G +GP G  G +G  G  GP GP GP G+ G+ G +GE G  G 
Sbjct: 1110 QGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGS 1169

Query: 516  RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP------------EGPPGSPGPSGP--- 560
            +G  G +G  G  G  GP GQPGP G  G PGP            EGP G PGP GP   
Sbjct: 1170 KGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGL 1229

Query: 561  QGKPGIAGKTGSPGQRGAMGPKGEPGIQGP---PGLPGPPGPPG 601
            QG PG  G+ G  G  G MGP G PG +GP   PG  GP GPPG
Sbjct: 1230 QGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPG 1273



 Score =  144 bits (362), Expect = 3e-34
 Identities = 78/158 (49%), Positives = 92/158 (58%), Gaps = 15/158 (9%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGG---RGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
            +G  GPPGP G +G +G  GP G     GP+G  G  G  G +GP+G PG  GPVG +G 
Sbjct: 1173 KGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGL 1232

Query: 513  VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPP---GPEGPP---GSPGPSGPQGKPGI 566
             GP   PG KG  G  G  GP G PGP+G  G P   GP+GPP   G+PG  G +G+PG 
Sbjct: 1233 PGP---PGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGE 1289

Query: 567  AGKTGSPGQRGAMGPK---GEPGIQGPPGLPGPPGPPG 601
            AG+ G PG+ G  GPK   GE G  GP G  GPPGP G
Sbjct: 1290 AGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKG 1327



 Score =  143 bits (361), Expect = 4e-34
 Identities = 74/151 (49%), Positives = 84/151 (55%), Gaps = 3/151 (1%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           RG  GPPGP G  G  G  G  G RG  G  G  G  G  G  G PGE G  G+ GP GP
Sbjct: 594 RGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGP 653

Query: 516 RGFPGLKGSKGSFGTGGPRG---QPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572
            G PG  G +G  G  GPRG   +PGP+G +GP GP GPPG PG +G  G+PG  G  G 
Sbjct: 654 PGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGP 713

Query: 573 PGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G+ G  G +G PG QG PG  G  GPPG +
Sbjct: 714 QGEPGPPGQQGNPGAQGLPGPQGAIGPPGEK 744



 Score =  143 bits (360), Expect = 5e-34
 Identities = 78/152 (51%), Positives = 89/152 (58%), Gaps = 12/152 (7%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP---V 513
           G PGPPG  G +GD G  GP G  G  G  G LGP GP GP G PG  G  G+ GP   V
Sbjct: 652 GPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNV 711

Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---PGSPGPSGPQGKPGIAGKT 570
           GP+G PG  G +G+    G +G PGP+G IGPPG +GP   PG PG  G  G PG  GK 
Sbjct: 712 GPQGEPGPPGQQGN---PGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKE 768

Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           G PG++G  GP   PG QGP G PGP G  G+
Sbjct: 769 GPPGEKGGQGP---PGPQGPIGYPGPRGVKGA 797



 Score =  142 bits (359), Expect = 7e-34
 Identities = 77/165 (46%), Positives = 87/165 (52%), Gaps = 18/165 (10%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRG------PKGDPGSLGPLGPQGPQGQPGEAGPVGER 510
           G  GPPG  G KG+ G  GP G RG      P G PG  G  G  G +G PG+ GP G+R
Sbjct: 571 GPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDR 630

Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQP---GPKGDIGPPGPEGPPGSP---------GPS 558
           G  G  G PG KG +G  G  GP G P   G +GD G  GP G PG P         GP 
Sbjct: 631 GFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPP 690

Query: 559 GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           GP G PG+ G  G PG +G +GP+GEPG  G  G PG  G PG Q
Sbjct: 691 GPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQ 735



 Score =  142 bits (359), Expect = 7e-34
 Identities = 78/155 (50%), Positives = 91/155 (58%), Gaps = 24/155 (15%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG---EAGPVGERGP 512
            +GAPG PGP G +G   + GPVG +G  G PG  GP GP GP G PG   ++GP GE+G 
Sbjct: 1428 QGAPGKPGPDGLRG---IPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGH 1484

Query: 513  ---VGPRGFPGLKGSKGSFGTGGPRGQPGPKGD------IGPPGPEGPPGSPGPSGPQGK 563
               +G  G PG +G KG  G  GP+G  GPKG+       GP GP GPPG PGP GP+G 
Sbjct: 1485 PGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGA 1544

Query: 564  PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPG 598
             G +G T         GPKGE G  GPPG PGPPG
Sbjct: 1545 KGSSGPT---------GPKGEAGHPGPPGPPGPPG 1570



 Score =  142 bits (358), Expect = 9e-34
 Identities = 74/151 (49%), Positives = 83/151 (54%), Gaps = 6/151 (3%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            RG PGPPGP G +G   + GP G +G  GD G +GP GP GP+G  G  G  G +GP G 
Sbjct: 1218 RGFPGPPGPVGLQG---LPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGG 1274

Query: 516  RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
             G PG  G KG  G  G  G PG  G  GP G  G  G  GPSG  G PG  G  G  G 
Sbjct: 1275 IGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGP 1334

Query: 576  RGAMGPKGEPGIQGPPGLPGP---PGPPGSQ 603
            +G+ GP G PG  GPPG PGP    GPPG +
Sbjct: 1335 KGSPGPVGFPGDPGPPGEPGPAGQDGPPGDK 1365



 Score =  141 bits (355), Expect = 2e-33
 Identities = 86/210 (40%), Positives = 95/210 (45%), Gaps = 66/210 (31%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPL------------------------ 492
            GA G PGPRG +G  G KG     GP+G PG  GP+                        
Sbjct: 1195 GADGEPGPRGQQGLFGQKGD---EGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPP 1251

Query: 493  ---------------GPQGP------------QGQPGEAGP---VGERGPVGPRGFPGLK 522
                           GPQGP            +G+PGEAG     GE GP GP+G  G K
Sbjct: 1252 GPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEK 1311

Query: 523  GSKGSFGTGGPRGQPGPKGDIGP---------PGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
            G  G  G  GP G  GP GD GP         PG  GPPG PGP+G  G PG  G  G P
Sbjct: 1312 GESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEP 1371

Query: 574  GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            GQ G+ GP GEPG  GPPG  GPPGP G +
Sbjct: 1372 GQTGSPGPTGEPGPSGPPGKRGPPGPAGPE 1401



 Score =  140 bits (353), Expect = 3e-33
 Identities = 73/153 (47%), Positives = 86/153 (56%), Gaps = 3/153 (1%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           +GA GPPG +G  G  G+ G  G  GP G PG  GP G +G QG PG  GP+G  GP G 
Sbjct: 735 QGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGV 794

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPE---GPPGSPGPSGPQGKPGIAGKTGS 572
           +G  G++G KG+ G  G  G PG KGD+G  G     GPPG  G  GP+G  G  G  G 
Sbjct: 795 KGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGD 854

Query: 573 PGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
           PG  G  G KG+ G+ G PG PG  GP GS  F
Sbjct: 855 PGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGF 887



 Score =  134 bits (336), Expect = 3e-31
 Identities = 74/168 (44%), Positives = 86/168 (51%), Gaps = 21/168 (12%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG----- 511
            G PGPPG +G  G  G +G  G  GP G PG  GP G +G  G  G  GPVG  G     
Sbjct: 1018 GPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNE 1077

Query: 512  ----PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA 567
                P GP G PG +G  G+ G  G  G+PGP+G  GP G +G PG  GP GP G+ G+ 
Sbjct: 1078 GPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQ 1137

Query: 568  GKTGSPGQRGAMGPKGEPGIQGPPGLP------------GPPGPPGSQ 603
            G  G PG  G +GP GE G +G  G P            GPPGP G Q
Sbjct: 1138 GPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQ 1185



 Score =  132 bits (332), Expect = 9e-31
 Identities = 75/169 (44%), Positives = 87/169 (51%), Gaps = 24/169 (14%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG---------EAGPV 507
           G  GPPGP G  G+ G  G VG RG  G+PG  G LGP+GP G PG         + GP 
Sbjct: 649 GPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPK 708

Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGP---------PGPEGPPGSPGPS 558
           G  GP G  G PG +G+ G+ G  GP+G  GP G+ GP         PG +GPPG PG  
Sbjct: 709 GNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKE 768

Query: 559 GP------QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           GP      QG PG  G  G PG RG  G  G  G++G  G  G  G PG
Sbjct: 769 GPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPG 817



 Score =  130 bits (327), Expect = 3e-30
 Identities = 79/191 (41%), Positives = 95/191 (49%), Gaps = 45/191 (23%)

Query: 456 RGAPGP------PGPRGFKGDMGVKGPVGGRGPKGDPG------------SLGPLGPQGP 497
           +G PGP      PGPRG KG  G++G  G +G KG+ G              G +GP GP
Sbjct: 777 QGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGP 836

Query: 498 QGQ------PGEAGPVGERGPVGP------------RGFPGLKGSKGSFGTGGPRGQPGP 539
           +G+       G  GP G+ GP+GP             G+PG +G KGS G  G  G  G 
Sbjct: 837 RGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGE 896

Query: 540 KGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR---GAMGPKGEP------GIQGP 590
           KG  G PG  GP G  GP+GP+G+ G  G TG PG +   G  GP G P      G QGP
Sbjct: 897 KGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGP 956

Query: 591 PGLPGPPGPPG 601
            G PGP GPPG
Sbjct: 957 TGFPGPKGPPG 967



 Score =  117 bits (292), Expect = 4e-26
 Identities = 78/213 (36%), Positives = 91/213 (42%), Gaps = 56/213 (26%)

Query: 444 QHGE--ILRNVTILRGAPGPPGPRGFKGDMGVKGPVGG------RGPKGDPGSLGPLGPQ 495
           Q GE  I+    ++ G PGP GP G  G  G  GP G       RGP G PG  G  G  
Sbjct: 454 QKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLP 513

Query: 496 GPQGQP----------GEAGPVGE--------------------RGPVGPRGFPGLKGSK 525
           GP G            G+AG  G                     RGP GP G  G  G  
Sbjct: 514 GPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPV 573

Query: 526 GSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEP 585
           G  G+GG +G+PG   D+GP GP G  G PGP+G  G+ G AG  G+ G  G  GPKG+ 
Sbjct: 574 GPPGSGGLKGEPG---DVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDR 630

Query: 586 GIQG---------------PPGLPGPPGPPGSQ 603
           G  G               P G PGPPG  G +
Sbjct: 631 GFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGER 663



 Score =  115 bits (288), Expect = 1e-25
 Identities = 75/196 (38%), Positives = 86/196 (43%), Gaps = 46/196 (23%)

Query: 453 TILRGAPGPPGPRGFKGD-------MGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG 505
           TI  G  GP G +G KG+       M ++GP G  GP G PG  G +GP G  G PGE G
Sbjct: 440 TIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERG 499

Query: 506 PVGERGPVGPRGFPGLKGSK----------GSFGTGGP--------------------RG 535
           P G  G  G  G PG  G+           G  G+ GP                    RG
Sbjct: 500 PPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRG 559

Query: 536 QPGPKGDIGPPGPEGPPGS------PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQG 589
             GP G  G PGP GPPGS      PG  GPQG  G+ G    PG  G  G +G  G  G
Sbjct: 560 PAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGP---PGPAGKPGRRGRAGSDG 616

Query: 590 PPGLPGPPGPPGSQSF 605
             G+PG  GP G + F
Sbjct: 617 ARGMPGQTGPKGDRGF 632



 Score =  101 bits (252), Expect = 2e-21
 Identities = 53/105 (50%), Positives = 62/105 (59%), Gaps = 9/105 (8%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            L+G  GP G +G  G +G+ GP G +G KGD G  GP G  GP+G+ G  GP G  GP G
Sbjct: 1472 LKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPG 1531

Query: 515  PRGFPGL---KGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPG 556
            P G PG    KG+KGS       G  GPKG+ G PGP GPPG PG
Sbjct: 1532 PPGLPGPPGPKGAKGS------SGPTGPKGEAGHPGPPGPPGPPG 1570



 Score = 94.0 bits (232), Expect = 4e-19
 Identities = 48/94 (51%), Positives = 54/94 (57%), Gaps = 3/94 (3%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            L G  GPPG +G KGD G+ GP G  GPKG+ G  GP GP GP G PG  GP G   P G
Sbjct: 1487 LIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPG---PKG 1543

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548
             +G  G  G KG  G  GP G PGP G++  P P
Sbjct: 1544 AKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLP 1577



 Score = 82.8 bits (203), Expect = 8e-16
 Identities = 43/86 (50%), Positives = 51/86 (59%), Gaps = 6/86 (6%)

Query: 519 PGLKGSKGSF--GTGGPRGQPGPKGD--IGPPGP--EGPPGSPGPSGPQGKPGIAGKTGS 572
           PG+  ++ +   G GGPRG+ G KG+  I  PG   EGPPG  GP+G  G PG  G TG 
Sbjct: 432 PGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQ 491

Query: 573 PGQRGAMGPKGEPGIQGPPGLPGPPG 598
            G  G  GP G PG+ G  GLPGPPG
Sbjct: 492 VGDPGERGPPGRPGLPGADGLPGPPG 517



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 26/54 (48%), Positives = 28/54 (51%)

Query: 450  RNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE 503
            + +T   G  GPPGP G  G  G KG  G  GP G  G  G  GP GP G PGE
Sbjct: 1518 QGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGE 1571



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 30/76 (39%), Positives = 35/76 (46%), Gaps = 18/76 (23%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQG------------------P 497
            RG PGP G  G KG+ G+ GP G  GP G PG  GP GP+G                  P
Sbjct: 1503 RGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGP 1562

Query: 498  QGQPGEAGPVGERGPV 513
             G PG  G V +  P+
Sbjct: 1563 PGPPGPPGEVIQPLPI 1578


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  158 bits (400), Expect = 1e-38
 Identities = 78/146 (53%), Positives = 85/146 (58%), Gaps = 3/146 (2%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            GAPGP GP G  GD G  GP G  GP G  G+ GP GPQGP+G  GE G  G+RG  G R
Sbjct: 1052 GAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHR 1111

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
            GF GL+G     G  G  G+ GP G  GP GP GPPGS G  G  G  G+ G  G PG R
Sbjct: 1112 GFSGLQGPP---GPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPR 1168

Query: 577  GAMGPKGEPGIQGPPGLPGPPGPPGS 602
            G  G  G  G  GPPG PGPPGPP +
Sbjct: 1169 GRTGDAGPVGPPGPPGPPGPPGPPSA 1194



 Score =  154 bits (388), Expect = 3e-37
 Identities = 75/154 (48%), Positives = 88/154 (57%), Gaps = 6/154 (3%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG------EAGPVGE 509
           +G  GPPGP+G  G+ G  G  G  G KG+PG +G  GP GP G+ G      E GP G 
Sbjct: 421 QGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGL 480

Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGK 569
            GP G RG PG +G  G+ G  GP+G  G +G  GP GP+G PG  G  G  G PG  G 
Sbjct: 481 PGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGL 540

Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           TGSPG  G  G  G PG  G  G PGPPGPPG++
Sbjct: 541 TGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGAR 574



 Score =  154 bits (388), Expect = 3e-37
 Identities = 78/158 (49%), Positives = 89/158 (56%), Gaps = 18/158 (11%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           RG PGPPGP GF G  G  G  G +G  GD G+ G  GP GP      AGP G  GP+G 
Sbjct: 802 RGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGP------AGPAGPPGPIGN 855

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEG---PPGSPGPSGPQGKPGIAGKTGS 572
            G PG KG++GS G  G  G PG  G +GPPGP G   PPG PGP+G +G  G  G+TG 
Sbjct: 856 VGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGP 915

Query: 573 PGQRGAMGP---------KGEPGIQGPPGLPGPPGPPG 601
            G+ G +GP         KG PG  GP G PG PGP G
Sbjct: 916 AGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQG 953



 Score =  150 bits (380), Expect = 2e-36
 Identities = 77/158 (48%), Positives = 86/158 (54%), Gaps = 9/158 (5%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            RG  GP GP G  G  G  GPVG  G  GD G  GP GP GP G  G  GP G +GP G 
Sbjct: 1036 RGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGD 1095

Query: 516  RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
            +G  G +G +G  G  G  G  GP G  G PG +GP G+ GP+GP+G PG AG  G  G 
Sbjct: 1096 KGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGL 1155

Query: 576  RGAMGPKGEPGIQ---------GPPGLPGPPGPPGSQS 604
             G  GP G PG +         GPPG PGPPGPPG  S
Sbjct: 1156 NGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPS 1193



 Score =  150 bits (378), Expect = 4e-36
 Identities = 75/157 (47%), Positives = 90/157 (57%), Gaps = 9/157 (5%)

Query: 456  RGAPGPPGPRGFKGD---MGVKGPVGGRGPKGDPGSLG------PLGPQGPQGQPGEAGP 506
            RG+ GPPG  GF G    +G  GP G  GP G PG  G      P G  GP G+PGE GP
Sbjct: 865  RGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGP 924

Query: 507  VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566
             G  GP G +G PG  G  G+ GT GP+G  G +G +G PG  G  G PG  GP G+PG 
Sbjct: 925  PGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGK 984

Query: 567  AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
             G +G+ G+RG  GP G PG+ GPPG  G  G PG++
Sbjct: 985  QGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAE 1021



 Score =  149 bits (377), Expect = 6e-36
 Identities = 76/156 (48%), Positives = 88/156 (56%), Gaps = 9/156 (5%)

Query: 455 LRGAPGPPGPRGFKG------DMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE---AG 505
           L G PG PGP+GF+G      + G  GP+G RGP G PG  G  G  G  G+PGE    G
Sbjct: 189 LPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPG 248

Query: 506 PVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPG 565
           P G RG  G  G PG+KG +G  G  G +G  GP G  G PG  G  G+PG  GP+G PG
Sbjct: 249 PQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPG 308

Query: 566 IAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
             G+ G+PG  GA G  G  G  GPPG  GP GPPG
Sbjct: 309 ERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPG 344



 Score =  149 bits (377), Expect = 6e-36
 Identities = 77/155 (49%), Positives = 86/155 (55%), Gaps = 9/155 (5%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE---------AGP 506
           RGA G PGP+G +GD G KG  G  G  G  G  GP+GP GP G PG+         AGP
Sbjct: 733 RGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGP 792

Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566
            G RG  G RG PG  G  G  G  G  GQPG KG+ G  G +G  G PGP+GP G PG 
Sbjct: 793 TGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGP 852

Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  G+PG +GA G  G PG  G PG  G  GPPG
Sbjct: 853 IGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPG 887



 Score =  149 bits (376), Expect = 7e-36
 Identities = 83/183 (45%), Positives = 93/183 (50%), Gaps = 36/183 (19%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGS---------LGPLGPQGPQGQPGEAGPV 507
           G PG  G RGF G  G KG  G  GPKG+PGS         +GP G  G +G+PG  GP 
Sbjct: 260 GLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPA 319

Query: 508 GERG---------------PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP 552
           G RG               P GP GFPG  G+KG  G  GPRG  GP+G  G PGP GP 
Sbjct: 320 GARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPA 379

Query: 553 GSPGPS------------GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPP 600
           G+ GP+            G  G PGIAG  G PG RG  GP+G  G  GP G  G PG P
Sbjct: 380 GAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAP 439

Query: 601 GSQ 603
           GS+
Sbjct: 440 GSK 442



 Score =  149 bits (376), Expect = 7e-36
 Identities = 82/159 (51%), Positives = 88/159 (55%), Gaps = 15/159 (9%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PGPPG RG  G  G  G  G  GPKG  G  G  GP GP+G PGEAG  GE G  G +
Sbjct: 479 GLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAK 538

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS---------PGPSGPQGKPGIA 567
           G   L GS GS G  G  G PGP G  G PGP GPPG+         PGP G  G+PG A
Sbjct: 539 G---LTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA 595

Query: 568 GKTGSPGQRGAMGP---KGEPGIQGPPGLPGPPGPPGSQ 603
           G+ G PG  GA+GP    GE G QGPPG  GP G  G Q
Sbjct: 596 GERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQ 634



 Score =  149 bits (375), Expect = 9e-36
 Identities = 80/166 (48%), Positives = 91/166 (54%), Gaps = 21/166 (12%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQ---PGEAGPVGERGPV 513
            G  GPPGP G  G  G KGP G  GP G PG +GP GP GP G+   PG  GP G  G  
Sbjct: 890  GNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTP 949

Query: 514  GPRGF---------PGLKGSKGSFGTGGPRGQPGPKG------DIGPPGPEGPPGSPGPS 558
            GP+G          PG +G +G  G  GP G+PG +G      + GPPGP GPPG  GP 
Sbjct: 950  GPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPP 1009

Query: 559  GPQGKPGIAGKTGSPGQ---RGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  G+ G  G  GSPG+    GA G +GE G  GPPG PG PG PG
Sbjct: 1010 GESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPG 1055



 Score =  148 bits (374), Expect = 1e-35
 Identities = 76/149 (51%), Positives = 87/149 (58%), Gaps = 3/149 (2%)

Query: 456 RGAPGPPG---PRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
           RG PGPPG   P G  G+ G +GP G  GP G+ G  GP G  G QG PG AGP GE G 
Sbjct: 598 RGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGK 657

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572
            G +G PG  G+ G  G  G RG PG +G  GPPGP GP G+ G  G  G  G AG  G+
Sbjct: 658 PGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGA 717

Query: 573 PGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           PG +GA G +G PG +G  GLPGP G  G
Sbjct: 718 PGSQGAPGLQGMPGERGAAGLPGPKGDRG 746



 Score =  147 bits (370), Expect = 4e-35
 Identities = 73/153 (47%), Positives = 82/153 (53%), Gaps = 6/153 (3%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG------PVGER 510
           G+PG  G RG  G +G  GP G  G KG+ G  GP GP G +G PG+ G      P G  
Sbjct: 755 GSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFA 814

Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKT 570
           GP G  G PG KG  G  G  G  G PGP G  GPPGP G  G+PG  G +G  G  G T
Sbjct: 815 GPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGAT 874

Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           G PG  G +GP G  G  GPPG PGP G  G +
Sbjct: 875 GFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGK 907



 Score =  145 bits (366), Expect = 1e-34
 Identities = 75/159 (47%), Positives = 87/159 (54%), Gaps = 12/159 (7%)

Query: 456 RGAPGPPGPRGFKGDM---------GVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP 506
           RG+PGP GP+G  G+          G KG  G  G  G  G  GP GP G  G+PG  GP
Sbjct: 511 RGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGP 570

Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS---PGPSGPQGK 563
            G RG  G  GFPG KG+ G  G  G RG PGP G +GP G +G  G+   PGP+GP G+
Sbjct: 571 PGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGE 630

Query: 564 PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
            G  G  GSPG +G  GP G PG  G PG  G PG  G+
Sbjct: 631 RGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGA 669



 Score =  145 bits (365), Expect = 1e-34
 Identities = 72/147 (48%), Positives = 81/147 (55%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           RG PGP G RG  G  G+ G  G RG  G  G+ G  GP GP+G+PG  G  G  G +GP
Sbjct: 244 RGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGP 303

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
           RG PG +G  G+ G  G RG  G  G  GPPGP GP G PG  G  G  G AG  G  G 
Sbjct: 304 RGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGS 363

Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPGS 602
            G  G +GEPG  GP G  GP G PG+
Sbjct: 364 EGPQGVRGEPGPPGPAGAAGPAGNPGA 390



 Score =  144 bits (364), Expect = 2e-34
 Identities = 75/146 (51%), Positives = 80/146 (54%), Gaps = 3/146 (2%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           RG  GPPGP G +G  G  G  G +G  G PG+ G  G  G QG PGE G  G  GP G 
Sbjct: 685 RGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGD 744

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
           RG  G KG+ GS G  G RG  GP   IGPPGP G PG  G SGP G  G  G  G+PG 
Sbjct: 745 RGDAGPKGADGSPGKDGVRGLTGP---IGPPGPAGAPGDKGESGPSGPAGPTGARGAPGD 801

Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPG 601
           RG  GP G  G  GPPG  G PG  G
Sbjct: 802 RGEPGPPGPAGFAGPPGADGQPGAKG 827



 Score =  143 bits (361), Expect = 4e-34
 Identities = 76/146 (52%), Positives = 82/146 (56%), Gaps = 3/146 (2%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           RGA G PGP G  G  G +G  G RG  G  G  GP GP G +G PG AGP G  G  G 
Sbjct: 469 RGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGR 528

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
            G  GL G+KG   TG P G PGP G  GPPGP G  G PGP GP G  G AG  G PG 
Sbjct: 529 PGEAGLPGAKGL--TGSP-GSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGP 585

Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPG 601
           +GA G  G+ G +G PG PG  GP G
Sbjct: 586 KGAAGEPGKAGERGVPGPPGAVGPAG 611



 Score =  143 bits (360), Expect = 5e-34
 Identities = 79/172 (45%), Positives = 86/172 (50%), Gaps = 24/172 (13%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
           L G  GPPGP G  GD G  GP G  GP G  G+ G  G  GP G  G AGP G  G  G
Sbjct: 765 LTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPG 824

Query: 515 PRGFPGLKGSKGSFGT---GGPRGQPGPKGDIGPPGPE---------------------G 550
            +G PG  G+KG  G     GP G PGP G++G PG +                     G
Sbjct: 825 AKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVG 884

Query: 551 PPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           PPG  G +GP G PG AGK G  G RG  GP G PG  GPPG PGP G  GS
Sbjct: 885 PPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGS 936



 Score =  142 bits (358), Expect = 9e-34
 Identities = 76/167 (45%), Positives = 86/167 (51%), Gaps = 18/167 (10%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           GA GPPGP G  G  G  G VG +G  G  G  G  GPQG +G+PG  GP G  GP G  
Sbjct: 329 GAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNP 388

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           G  G  G+KG+ G  G  G PG  G  GP GP+GP G PGP G  G+PG  G  G  G +
Sbjct: 389 GADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAK 448

Query: 577 GAMGP---------------KGEPGIQGPPGLPGPPGP---PGSQSF 605
           G  GP               +G  G  GP GLPGPPG    PGS+ F
Sbjct: 449 GEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGF 495



 Score =  141 bits (356), Expect = 2e-33
 Identities = 73/162 (45%), Positives = 90/162 (55%), Gaps = 15/162 (9%)

Query: 456 RGAPGPPGPRGFKGDM------GVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509
           RG PGPPG  G  G+       G +GP G +G +G PG+ G  G +G +G  G  G  G+
Sbjct: 220 RGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGD 279

Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS---------PGPSGP 560
            GP GP+G PG  G  G+ G  GPRG PG +G  G PGP G  G+         PGP+GP
Sbjct: 280 AGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGP 339

Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
            G PG  G  G+ G+ G  GP+G  G QG  G PGPPGP G+
Sbjct: 340 AGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGA 381



 Score =  141 bits (355), Expect = 2e-33
 Identities = 76/154 (49%), Positives = 82/154 (53%), Gaps = 9/154 (5%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPVGERGPV 513
           G  GPPGP G  G  G KG  G  GP G    PG+ G +GP GP G  G  GP G  G  
Sbjct: 845 GPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKE 904

Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
           G +G  G  G  G  G  GP G PGP G+ G PG +GP G+PG  GPQG  G  G  G P
Sbjct: 905 GGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLP 964

Query: 574 GQRGAM------GPKGEPGIQGPPGLPGPPGPPG 601
           GQRG        GP GEPG QGP G  G  GPPG
Sbjct: 965 GQRGERGFPGLPGPSGEPGKQGPSGASGERGPPG 998



 Score =  141 bits (355), Expect = 2e-33
 Identities = 80/187 (42%), Positives = 88/187 (47%), Gaps = 42/187 (22%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRG---------PKGDPGSLGPLG------PQGPQGQP 501
            GAPG PGP+G  G  GV G  G RG         P G+PG  GP G      P GP G P
Sbjct: 944  GAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPP 1003

Query: 502  GEAGPV---------------------------GERGPVGPRGFPGLKGSKGSFGTGGPR 534
            G AGP                            GE GP GP G PG  G+ G  G  G  
Sbjct: 1004 GLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKS 1063

Query: 535  GQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP 594
            G  G  G  GP GP GP G+ GP+GPQG  G  G+TG  G RG  G +G  G+QGPPG P
Sbjct: 1064 GDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPP 1123

Query: 595  GPPGPPG 601
            G PG  G
Sbjct: 1124 GSPGEQG 1130



 Score =  138 bits (348), Expect = 1e-32
 Identities = 75/160 (46%), Positives = 84/160 (52%), Gaps = 15/160 (9%)

Query: 456 RGAPGPPGPRGFKGD------MGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509
           RG PG PGP G +G+       G  GP G  GP G PG++G  G  GPQG  G  GP G 
Sbjct: 310 RGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGV 369

Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP------GPSGPQGK 563
           RG  GP   PG  G+ G  G  G  GQPG KG  G PG  G PG P      GP GP G 
Sbjct: 370 RGEPGP---PGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGP 426

Query: 564 PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           PG  G +G PG  G+ G  G  G  GP G+ GPPGP G +
Sbjct: 427 PGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEE 466



 Score =  138 bits (348), Expect = 1e-32
 Identities = 79/175 (45%), Positives = 88/175 (50%), Gaps = 30/175 (17%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGG---------RGPKGDPGSLGPLGPQGP---QGQPGEA 504
           G PGPPG RG  G MG  GP G          RG  G PG++GP G  G    QG PG A
Sbjct: 566 GPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPA 625

Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKG---DIGPPGP------------- 548
           GP GERG  GP G PG +G  G  G  G  G+PG +G   D+G PGP             
Sbjct: 626 GPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGER 685

Query: 549 --EGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
             +GPPG  GP G  G PG  G  G  G  GA G +G PG+QG PG  G  G PG
Sbjct: 686 GVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPG 740



 Score =  138 bits (347), Expect = 2e-32
 Identities = 75/161 (46%), Positives = 86/161 (53%), Gaps = 12/161 (7%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLG---PLGPQGPQGQPGEAGPVGERGPV 513
           G  G PG +G  GD+G  GP G RG +G PG  G   P GP GP+G  G  G  G +G  
Sbjct: 653 GEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDA 712

Query: 514 GPRGFPGLKGSKGSFGTGGPRGQ---PGPKGDIGPPGPEGPPGSPGP------SGPQGKP 564
           G  G PG +G+ G  G  G RG    PGPKGD G  GP+G  GSPG       +GP G P
Sbjct: 713 GAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPP 772

Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
           G AG  G  G+ G  GP G  G +G PG  G PGPPG   F
Sbjct: 773 GPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGF 813



 Score =  136 bits (342), Expect = 6e-32
 Identities = 82/192 (42%), Positives = 90/192 (46%), Gaps = 45/192 (23%)

Query: 455 LRGAPGPPGPRGFKGDMG---------VKGPVGGRGPKGDPGSLGPLGPQGPQ------- 498
           +RG PGPPGP G  G  G          KG  G  G  G PG  G  GP GPQ       
Sbjct: 369 VRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPG 428

Query: 499 -----------------GQPGEAGPVGERGPVGPRGFPGLKGSKGSFG----------TG 531
                            G  GE GPVG +GP GP G  G +G++G  G           G
Sbjct: 429 PKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERG 488

Query: 532 GP--RGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQG 589
           GP  RG PG  G  GP GP G  GSPGP+GP+G PG AG+ G  G  GA G  G PG  G
Sbjct: 489 GPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPG 548

Query: 590 PPGLPGPPGPPG 601
           P G  GPPGP G
Sbjct: 549 PDGKTGPPGPAG 560



 Score =  135 bits (340), Expect = 1e-31
 Identities = 76/157 (48%), Positives = 84/157 (53%), Gaps = 12/157 (7%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP---LGPQGPQGQPGEAGPVGERGPV 513
           GA GPPGP G  G+ G +GP G  G +G PG  GP    G  G QG PG+ G  G  G  
Sbjct: 617 GAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGAR 676

Query: 514 GPRGFPGLKGSKGSFGTGGPR------GQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA 567
           G RGFPG +G +G  G  GPR      G  G KGD G PG  G  G+PG  G  G+ G A
Sbjct: 677 GERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAA 736

Query: 568 GKTGSPGQRGAMGPK---GEPGIQGPPGLPGPPGPPG 601
           G  G  G RG  GPK   G PG  G  GL GP GPPG
Sbjct: 737 GLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPG 773



 Score =  134 bits (337), Expect = 2e-31
 Identities = 77/171 (45%), Positives = 90/171 (52%), Gaps = 24/171 (14%)

Query: 456 RGAPGPPGPRGFKGDMGVKG------PVGGRGPKGDPGSLGPLGPQGPQGQPGEAG---- 505
           +G  GP GPRG +G  GV+G      P G  GP G+PG+ G  G +G  G PG AG    
Sbjct: 352 KGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGF 411

Query: 506 --------PVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP---EGPPGS 554
                   P G  GP GP+G  G  G+ GS G  G +G+PGP G  GPPGP   EG  G+
Sbjct: 412 PGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGA 471

Query: 555 PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPG---LPGPPGPPGS 602
            G  GP G PG  G+ G PG RG  G  G  G +GP G    PGP GP GS
Sbjct: 472 RGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGS 522



 Score =  134 bits (336), Expect = 3e-31
 Identities = 74/156 (47%), Positives = 84/156 (53%), Gaps = 9/156 (5%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGS---LGPLGPQGPQGQPGEAGPVGERG 511
           L G+PG PGP G  G  G  G  G  GP G PG+    G +G  GP+G  GE G  GERG
Sbjct: 540 LTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERG 599

Query: 512 PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP---GSPGPSGPQGKPGIAG 568
             GP G  G  G  G  G  GP G  GP G+ G  GP G P   G PGP+GP G+ G  G
Sbjct: 600 VPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPG 659

Query: 569 KTGSPGQRGAMGP---KGEPGIQGPPGLPGPPGPPG 601
           + G PG  GA GP   +GE G  G  G+ GPPGP G
Sbjct: 660 EQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAG 695



 Score =  129 bits (324), Expect = 8e-30
 Identities = 74/166 (44%), Positives = 82/166 (49%), Gaps = 21/166 (12%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGP---KGDPGSLGPLGPQGPQGQPGEAGPVGERGP- 512
           G PG PG  G KG+ G +GP G  GP   +G+PG  GP G  GP G PG  G  G +G  
Sbjct: 341 GPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGAN 400

Query: 513 -----VGPRGFPGLKGSKGSFGTGGPRGQ---------PGPKGDIGPPGPEGPPGSPGPS 558
                 G  GFPG +G  G  G GGP G          PG KGD G  G  GP G  GP 
Sbjct: 401 GAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPP 460

Query: 559 GPQGKPGIAGKTGSPGQRGAMGPKGE---PGIQGPPGLPGPPGPPG 601
           GP G+ G  G  G PG  G  GP GE   PG +G PG  G  GP G
Sbjct: 461 GPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKG 506



 Score =  128 bits (322), Expect = 1e-29
 Identities = 73/168 (43%), Positives = 83/168 (49%), Gaps = 19/168 (11%)

Query: 450 RNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP--- 506
           +  T + G  G  GPRG +G  G  G  G  G  G PG  GP GP GP G  G   P   
Sbjct: 105 QETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLS 164

Query: 507 -------------VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPG 553
                         G  GP GPRG PG  G+ G  G  GP G+PG  G  GP GP GPPG
Sbjct: 165 YGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPG 224

Query: 554 SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            PG +G  G+   AGK G PG+RG  GP+G  G+ G  GLPG  G  G
Sbjct: 225 PPGKNGDDGE---AGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRG 269



 Score =  123 bits (308), Expect = 6e-28
 Identities = 70/168 (41%), Positives = 78/168 (46%), Gaps = 25/168 (14%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV--------- 507
           G  GP G  G +G  G  GP G  G  G PG  GP GP GP G PG  G           
Sbjct: 109 GVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYD 168

Query: 508 ----------GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP 557
                     G  GP GPRG PG  G+ G      P+G  GP G+ G PG  GP G  GP
Sbjct: 169 EKSTGGISVPGPMGPSGPRGLPGPPGAPG------PQGFQGPPGEPGEPGASGPMGPRGP 222

Query: 558 SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
            GP GK G  G+ G PG+ G  GP G  G +G PG  G PG  G + F
Sbjct: 223 PGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGF 270



 Score =  103 bits (257), Expect = 5e-22
 Identities = 62/133 (46%), Positives = 66/133 (49%), Gaps = 20/133 (15%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            GA GP GP+G +GD G  G  G RG KG  G  G  GP GP G PGE GP G  GP GPR
Sbjct: 1082 GARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPR 1141

Query: 517  GFPG---------LKGSKGSFGTGGPRGQPG------PKGDIGPPGPEGPPG-----SPG 556
            G PG         L G  G  G  GPRG+ G      P G  GPPGP GPP      S  
Sbjct: 1142 GPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFL 1201

Query: 557  PSGPQGKPGIAGK 569
            P  PQ K    G+
Sbjct: 1202 PQPPQEKAHDGGR 1214



 Score =  101 bits (252), Expect = 2e-21
 Identities = 62/151 (41%), Positives = 70/151 (46%), Gaps = 33/151 (21%)

Query: 478 GGRGPKGDPGSLGPLGPQGPQGQP--GEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRG 535
           G   P+G+   + P G + P  Q   G  GP G+ GP GPRG        G  G  G  G
Sbjct: 83  GAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRG------PAGPPGRDGIPG 136

Query: 536 QPGPKGDIGPPGPEGPPG----------------------SPGPSGPQGKPGIAGKTGSP 573
           QPG  G  GPPGP GPPG                       PGP GP G  G+ G  G+P
Sbjct: 137 QPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAP 196

Query: 574 GQRGAMGP---KGEPGIQGPPGLPGPPGPPG 601
           G +G  GP    GEPG  GP G  GPPGPPG
Sbjct: 197 GPQGFQGPPGEPGEPGASGPMGPRGPPGPPG 227



 Score = 79.3 bits (194), Expect = 9e-15
 Identities = 39/80 (48%), Positives = 47/80 (58%), Gaps = 9/80 (11%)

Query: 450  RNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGS---------LGPLGPQGPQGQ 500
            R  + L+G PGPPG  G +G  G  GP G RGP G  G+          GP+GP GP+G+
Sbjct: 1111 RGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGR 1170

Query: 501  PGEAGPVGERGPVGPRGFPG 520
             G+AGPVG  GP GP G PG
Sbjct: 1171 TGDAGPVGPPGPPGPPGPPG 1190



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 40/102 (39%), Positives = 45/102 (44%), Gaps = 25/102 (24%)

Query: 501 PGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGP 560
           PG   P GE  PV P G       + +       G  GPKGD GP GP GP G PG  G 
Sbjct: 82  PGAEVPEGECCPVCPDGSESPTDQETT-------GVEGPKGDTGPRGPRGPAGPPGRDGI 134

Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
            G+PG+                  PG  GPPG PGPPG  G+
Sbjct: 135 PGQPGL------------------PGPPGPPGPPGPPGLGGN 158



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 26/59 (44%), Positives = 29/59 (49%), Gaps = 8/59 (13%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLG--------PQGPQGQPGEAG 505
            L G PGP GP G +G  G  GPVG  GP G PG  GP          PQ PQ +  + G
Sbjct: 1155 LNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGG 1213


>gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score =  157 bits (398), Expect = 2e-38
 Identities = 86/185 (46%), Positives = 101/185 (54%), Gaps = 41/185 (22%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG------------EA 504
           G PG PG  G  G MG  G +G  GPKG+ G +GP GP GP+G+PG            E 
Sbjct: 387 GPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEV 446

Query: 505 GPVGERG---PVGPRGFPGLKGSKGSFGTGG---PRGQPG------------------PK 540
           GP G RG   P+GP+G  G KG  G  G  G   P+G+PG                  P 
Sbjct: 447 GPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPS 506

Query: 541 GDIGPPGPEGPPGSPGPSGPQ-----GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPG 595
           G IGPPG  GP G PG  GP      GKPG+AG  G PG+ GA+GP+G+PG+ GPPG PG
Sbjct: 507 GPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPG 566

Query: 596 PPGPP 600
           PPGPP
Sbjct: 567 PPGPP 571



 Score =  149 bits (377), Expect = 6e-36
 Identities = 82/166 (49%), Positives = 92/166 (55%), Gaps = 20/166 (12%)

Query: 456 RGAPGPPGPRGFK--GDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE---- 509
           +G PG PGP G    G  G  GP G RG  G PG+LGP G +GP G PG  GP GE    
Sbjct: 336 QGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLP 395

Query: 510 --RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD------------IGPPGPEGPPGSP 555
              GP+GP G  G  G KG  G  GP+G PGPKG+            +G  GP G  G P
Sbjct: 396 GIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLP 455

Query: 556 GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           GP GP+G+ G  G  G PG  G +GPKGEPGI G  GL GPPG PG
Sbjct: 456 GPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPG 501



 Score =  142 bits (357), Expect = 1e-33
 Identities = 87/195 (44%), Positives = 96/195 (49%), Gaps = 49/195 (25%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG--- 511
           L G PGPPG  G  G  G  GP G RG  G PG+LGP G +GP G PG  GP GE G   
Sbjct: 338 LPGLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPG 396

Query: 512 ---PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD------------IGPPGPEGPPGSPG 556
              P+GP G  G  G KG  G  GP+G PGPKG+            +G  GP G  G PG
Sbjct: 397 IPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPG 456

Query: 557 PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGI------QGPPG------------------ 592
           P GP+G+ G  G  G PG  G +GPKGEPGI      QGPPG                  
Sbjct: 457 PIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPG 516

Query: 593 ------LPGPPGPPG 601
                 LPGPPG PG
Sbjct: 517 PKGEPGLPGPPGFPG 531



 Score =  138 bits (347), Expect = 2e-32
 Identities = 85/179 (47%), Positives = 93/179 (51%), Gaps = 30/179 (16%)

Query: 457 GAPGPPGPRGFKG--DMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG------ 508
           G  GPPGP G  G    GV G  G +GP G PG+ G  GPQGP G PG  GP G      
Sbjct: 258 GMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGK 317

Query: 509 --ERGPVGPRGFPGLKGSKGSFGTGGPRGQPG--------PKGD---------IGPPGPE 549
             + G  G  GFPG KG +G  G  GP G PG        PKGD         +GP G +
Sbjct: 318 PGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEK 377

Query: 550 GPPGSPGPSGPQGKPG---IAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
           GP G+PG  GP G+PG   I G  G PG  G  GPKGE GI GP G PGP G PG Q F
Sbjct: 378 GPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGF 436



 Score =  135 bits (340), Expect = 1e-31
 Identities = 76/155 (49%), Positives = 87/155 (56%), Gaps = 14/155 (9%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PG PG  G  G  G KG +G +G  G  G  GP GP GP G PG    +G+ G  G  
Sbjct: 161 GMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG----IGKPGGPGLP 216

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGD-----IGPPGPEGPPGSPGPSGPQGKPGIA--GK 569
           G PG KG +G  G  GP+G  GPKGD      G PG +GPPG  GP GP G PG+   G 
Sbjct: 217 GQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGV 276

Query: 570 TGSPGQRGAM---GPKGEPGIQGPPGLPGPPGPPG 601
           TG PG +G +   G  GEPG QGP G+PG  GPPG
Sbjct: 277 TGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPG 311



 Score =  118 bits (296), Expect = 1e-26
 Identities = 72/174 (41%), Positives = 86/174 (49%), Gaps = 35/174 (20%)

Query: 462 PGPRGFKGDMGVKGPV-------GGRGPKGDPGSLGPLGPQGPQGQ-----PGEAGPVGE 509
           P PR  K  +  KG         G +GP+G+PG  GP GP G  G       G+ GP G 
Sbjct: 95  PAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGY 154

Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQ--GKPGIA 567
            G VG  G PG+ G  G+ G  G +G+ G KG+IGP G  GP G PGP G    GKPG  
Sbjct: 155 PG-VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGP 213

Query: 568 GKTGSPGQRGAMGPK--------------------GEPGIQGPPGLPGPPGPPG 601
           G  G PG +G  GPK                    G PG++GPPG+ GPPGP G
Sbjct: 214 GLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVG 267



 Score =  100 bits (250), Expect = 3e-21
 Identities = 65/149 (43%), Positives = 71/149 (47%), Gaps = 18/149 (12%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PG PG  G KG+ G+ G  G +GP G PG  GP GP GP G PG   P GE G  GP 
Sbjct: 471 GLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPG---PKGEPGLPGPP 527

Query: 517 GFPG--------LKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPG----SPGPSG---PQ 561
           GFPG        L G  G  G  GP+GQPG  G  GPPGP GPP     +P P G   P 
Sbjct: 528 GFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPD 587

Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGP 590
              GI G           G  G P  + P
Sbjct: 588 MGLGIDGVKPPHAYGAKKGKNGGPAYEMP 616



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 35/70 (50%), Positives = 42/70 (60%), Gaps = 8/70 (11%)

Query: 534 RGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGL 593
           RG+ GP+G+ GP GP GPPG PG     G PGI GK G  G  G     G+PG+ G PG 
Sbjct: 117 RGEQGPRGEPGPRGPPGPPGLPG----HGIPGIKGKPGPQGYPGV----GKPGMPGMPGK 168

Query: 594 PGPPGPPGSQ 603
           PG  G PG++
Sbjct: 169 PGAMGMPGAK 178



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 34/101 (33%), Positives = 43/101 (42%), Gaps = 8/101 (7%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
           L G PG PG  G +G  G+ GP G  GP G P  + P  P  PQG+      +G  G   
Sbjct: 540 LHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPP--PQGEYLPDMGLGIDGVKP 597

Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP 555
           P  +   KG  G    G     P    ++  P P  P G+P
Sbjct: 598 PHAYGAKKGKNG----GPAYEMPAFTAELTAPFP--PVGAP 632



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 40/131 (30%), Positives = 50/131 (38%), Gaps = 27/131 (20%)

Query: 491 PLGPQGPQGQPGEAG---PVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG 547
           PL PQ P   P +     P+G++ P  P    GL             G+  P    G   
Sbjct: 35  PLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLA-----------MGKEMPHLQYGKEY 83

Query: 548 PEGPPG----SPGPS-GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP----- 597
           P  P       P P  G +  P    +      RG  GP+GEPG +GPPG PG P     
Sbjct: 84  PHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIP 143

Query: 598 ---GPPGSQSF 605
              G PG Q +
Sbjct: 144 GIKGKPGPQGY 154


>gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score =  157 bits (398), Expect = 2e-38
 Identities = 86/185 (46%), Positives = 101/185 (54%), Gaps = 41/185 (22%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG------------EA 504
           G PG PG  G  G MG  G +G  GPKG+ G +GP GP GP+G+PG            E 
Sbjct: 387 GPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEV 446

Query: 505 GPVGERG---PVGPRGFPGLKGSKGSFGTGG---PRGQPG------------------PK 540
           GP G RG   P+GP+G  G KG  G  G  G   P+G+PG                  P 
Sbjct: 447 GPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPS 506

Query: 541 GDIGPPGPEGPPGSPGPSGPQ-----GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPG 595
           G IGPPG  GP G PG  GP      GKPG+AG  G PG+ GA+GP+G+PG+ GPPG PG
Sbjct: 507 GPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPG 566

Query: 596 PPGPP 600
           PPGPP
Sbjct: 567 PPGPP 571



 Score =  149 bits (377), Expect = 6e-36
 Identities = 82/166 (49%), Positives = 92/166 (55%), Gaps = 20/166 (12%)

Query: 456 RGAPGPPGPRGFK--GDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE---- 509
           +G PG PGP G    G  G  GP G RG  G PG+LGP G +GP G PG  GP GE    
Sbjct: 336 QGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLP 395

Query: 510 --RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD------------IGPPGPEGPPGSP 555
              GP+GP G  G  G KG  G  GP+G PGPKG+            +G  GP G  G P
Sbjct: 396 GIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLP 455

Query: 556 GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           GP GP+G+ G  G  G PG  G +GPKGEPGI G  GL GPPG PG
Sbjct: 456 GPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPG 501



 Score =  142 bits (357), Expect = 1e-33
 Identities = 87/195 (44%), Positives = 96/195 (49%), Gaps = 49/195 (25%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG--- 511
           L G PGPPG  G  G  G  GP G RG  G PG+LGP G +GP G PG  GP GE G   
Sbjct: 338 LPGLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPG 396

Query: 512 ---PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD------------IGPPGPEGPPGSPG 556
              P+GP G  G  G KG  G  GP+G PGPKG+            +G  GP G  G PG
Sbjct: 397 IPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPG 456

Query: 557 PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGI------QGPPG------------------ 592
           P GP+G+ G  G  G PG  G +GPKGEPGI      QGPPG                  
Sbjct: 457 PIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPG 516

Query: 593 ------LPGPPGPPG 601
                 LPGPPG PG
Sbjct: 517 PKGEPGLPGPPGFPG 531



 Score =  138 bits (347), Expect = 2e-32
 Identities = 85/179 (47%), Positives = 93/179 (51%), Gaps = 30/179 (16%)

Query: 457 GAPGPPGPRGFKG--DMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG------ 508
           G  GPPGP G  G    GV G  G +GP G PG+ G  GPQGP G PG  GP G      
Sbjct: 258 GMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGK 317

Query: 509 --ERGPVGPRGFPGLKGSKGSFGTGGPRGQPG--------PKGD---------IGPPGPE 549
             + G  G  GFPG KG +G  G  GP G PG        PKGD         +GP G +
Sbjct: 318 PGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEK 377

Query: 550 GPPGSPGPSGPQGKPG---IAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
           GP G+PG  GP G+PG   I G  G PG  G  GPKGE GI GP G PGP G PG Q F
Sbjct: 378 GPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGF 436



 Score =  135 bits (340), Expect = 1e-31
 Identities = 76/155 (49%), Positives = 87/155 (56%), Gaps = 14/155 (9%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PG PG  G  G  G KG +G +G  G  G  GP GP GP G PG    +G+ G  G  
Sbjct: 161 GMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG----IGKPGGPGLP 216

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGD-----IGPPGPEGPPGSPGPSGPQGKPGIA--GK 569
           G PG KG +G  G  GP+G  GPKGD      G PG +GPPG  GP GP G PG+   G 
Sbjct: 217 GQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGV 276

Query: 570 TGSPGQRGAM---GPKGEPGIQGPPGLPGPPGPPG 601
           TG PG +G +   G  GEPG QGP G+PG  GPPG
Sbjct: 277 TGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPG 311



 Score =  118 bits (296), Expect = 1e-26
 Identities = 72/174 (41%), Positives = 86/174 (49%), Gaps = 35/174 (20%)

Query: 462 PGPRGFKGDMGVKGPV-------GGRGPKGDPGSLGPLGPQGPQGQ-----PGEAGPVGE 509
           P PR  K  +  KG         G +GP+G+PG  GP GP G  G       G+ GP G 
Sbjct: 95  PAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGY 154

Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQ--GKPGIA 567
            G VG  G PG+ G  G+ G  G +G+ G KG+IGP G  GP G PGP G    GKPG  
Sbjct: 155 PG-VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGP 213

Query: 568 GKTGSPGQRGAMGPK--------------------GEPGIQGPPGLPGPPGPPG 601
           G  G PG +G  GPK                    G PG++GPPG+ GPPGP G
Sbjct: 214 GLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVG 267



 Score =  100 bits (250), Expect = 3e-21
 Identities = 65/149 (43%), Positives = 71/149 (47%), Gaps = 18/149 (12%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PG PG  G KG+ G+ G  G +GP G PG  GP GP GP G PG   P GE G  GP 
Sbjct: 471 GLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPG---PKGEPGLPGPP 527

Query: 517 GFPG--------LKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPG----SPGPSG---PQ 561
           GFPG        L G  G  G  GP+GQPG  G  GPPGP GPP     +P P G   P 
Sbjct: 528 GFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPD 587

Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGP 590
              GI G           G  G P  + P
Sbjct: 588 MGLGIDGVKPPHAYGAKKGKNGGPAYEMP 616



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 35/70 (50%), Positives = 42/70 (60%), Gaps = 8/70 (11%)

Query: 534 RGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGL 593
           RG+ GP+G+ GP GP GPPG PG     G PGI GK G  G  G     G+PG+ G PG 
Sbjct: 117 RGEQGPRGEPGPRGPPGPPGLPG----HGIPGIKGKPGPQGYPGV----GKPGMPGMPGK 168

Query: 594 PGPPGPPGSQ 603
           PG  G PG++
Sbjct: 169 PGAMGMPGAK 178



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 34/101 (33%), Positives = 43/101 (42%), Gaps = 8/101 (7%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
           L G PG PG  G +G  G+ GP G  GP G P  + P  P  PQG+      +G  G   
Sbjct: 540 LHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPP--PQGEYLPDMGLGIDGVKP 597

Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP 555
           P  +   KG  G    G     P    ++  P P  P G+P
Sbjct: 598 PHAYGAKKGKNG----GPAYEMPAFTAELTAPFP--PVGAP 632



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 40/131 (30%), Positives = 50/131 (38%), Gaps = 27/131 (20%)

Query: 491 PLGPQGPQGQPGEAG---PVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG 547
           PL PQ P   P +     P+G++ P  P    GL             G+  P    G   
Sbjct: 35  PLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLA-----------MGKEMPHLQYGKEY 83

Query: 548 PEGPPG----SPGPS-GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP----- 597
           P  P       P P  G +  P    +      RG  GP+GEPG +GPPG PG P     
Sbjct: 84  PHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIP 143

Query: 598 ---GPPGSQSF 605
              G PG Q +
Sbjct: 144 GIKGKPGPQGY 154


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  157 bits (397), Expect = 3e-38
 Identities = 80/149 (53%), Positives = 89/149 (59%), Gaps = 6/149 (4%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PG  GPRG  G +G  GP G  G KG+ G+ G  G  GP+G PGE G   E GP GP 
Sbjct: 753 GVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERG---ETGPPGPA 809

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           GFPG  G  G  G  G RG PG KG+ GPPG  GPPG  GP+GP G  G+ G+ GSPG  
Sbjct: 810 GFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGP 869

Query: 577 GAMGPKGEPGIQGPPGL---PGPPGPPGS 602
           GA G  G  G+ GPPG    PGPPGP GS
Sbjct: 870 GAAGFPGARGLPGPPGSNGNPGPPGPSGS 898



 Score =  157 bits (396), Expect = 3e-38
 Identities = 82/164 (50%), Positives = 91/164 (55%), Gaps = 18/164 (10%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE------------ 503
           RG  G PGP+G KG+ G  G  G  G  G  G  GP+GP GP GQPG+            
Sbjct: 731 RGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGI 790

Query: 504 AGP------VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP 557
           AGP       GE GP GP GFPG  G  G  G  G RG PG KG+ GPPG  GPPG  GP
Sbjct: 791 AGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGP 850

Query: 558 SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           +GP G  G+ G+ GSPG  GA G  G  G+ GPPG  G PGPPG
Sbjct: 851 AGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPG 894



 Score =  157 bits (396), Expect = 3e-38
 Identities = 79/149 (53%), Positives = 87/149 (58%), Gaps = 6/149 (4%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           RG  GPPGP GF G  G  G  GG+G +G PG  G  GP G  G PG +GP G  GP G 
Sbjct: 800 RGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGV 859

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
           +G  G  G  G+ G  G RG PGP G  G PGP GP GSPG  GP   PG AG TG+PG 
Sbjct: 860 KGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGP---PGPAGNTGAPGS 916

Query: 576 RGAMGPK---GEPGIQGPPGLPGPPGPPG 601
            G  GPK   G+PG +G PG  GPPG PG
Sbjct: 917 PGVSGPKGDAGQPGEKGSPGAQGPPGAPG 945



 Score =  151 bits (381), Expect = 2e-36
 Identities = 78/157 (49%), Positives = 85/157 (54%), Gaps = 12/157 (7%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGER------ 510
           G PGP GP G  G+ G +GP G  GP GD G  GP GPQG QG PG  GP GE       
Sbjct: 600 GGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEP 659

Query: 511 GPVGPRGFPGLKGSKGSFGTGGPR------GQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564
           GP G  G PG  G KG  G  G R      G PG +G  GPPGPEG  G+ GP GP G  
Sbjct: 660 GPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAA 719

Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           G  G  G PG+RG +G  G  G +G PG PG  G PG
Sbjct: 720 GTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPG 756



 Score =  150 bits (378), Expect = 4e-36
 Identities = 75/145 (51%), Positives = 79/145 (54%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G PGP GP G  GD G  GP G  G  G  GS G  GPQGP+G  GE G  G  G  G R
Sbjct: 1050 GPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHR 1109

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
            GFPG  G+ GS G  G +G  G  G  GP GP GP G PG  G  G PG  G  G  G R
Sbjct: 1110 GFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNR 1169

Query: 577  GAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  G +G PG  G PG PGPPG PG
Sbjct: 1170 GERGSEGSPGHPGQPGPPGPPGAPG 1194



 Score =  149 bits (376), Expect = 7e-36
 Identities = 77/162 (47%), Positives = 85/162 (52%), Gaps = 15/162 (9%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVG---------------GRGPKGDPGSLGPLGPQGPQGQP 501
           G PGP GPRG  G MG  GP G               G GP+G PG  G  GPQGP G  
Sbjct: 564 GPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPT 623

Query: 502 GEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQ 561
           G  G  G+ GP GP+G  GL G+ G  G  G  G+PGPKGD G PG  G  G  G  G +
Sbjct: 624 GPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGER 683

Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           G PG+AG  G  G  G  GP+G  G  GPPG PG  G PG Q
Sbjct: 684 GPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQ 725



 Score =  147 bits (370), Expect = 4e-35
 Identities = 75/148 (50%), Positives = 82/148 (55%), Gaps = 3/148 (2%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           RG PG  G  G +G  G  GP GG+G  G PG  G  G  G QG PGE G +G  GP G 
Sbjct: 683 RGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGD 742

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
           +G PG  G+ G  G  GPR   GP G IGPPGP G PG  G  G  G PGIAG  GSPG+
Sbjct: 743 KGEPGGPGADGVPGKDGPR---GPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGE 799

Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           RG  GP G  G  G PG  G PG  G +
Sbjct: 800 RGETGPPGPAGFPGAPGQNGEPGGKGER 827



 Score =  145 bits (366), Expect = 1e-34
 Identities = 75/159 (47%), Positives = 88/159 (55%), Gaps = 12/159 (7%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G+ G PGP G +G+ G  GP G  GP+G PG +G  GP+G  G PG+ G  G  G  GP+
Sbjct: 546 GSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQ 605

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGP------QGKPGIAGKT 570
           G PG  G  G  G  GP G  G KGD GPPGP+G  G PG  GP       G+PG  G  
Sbjct: 606 GPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDA 665

Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPP------GPPGSQ 603
           G+PG  G  G  G PG +GPPGL G P      GPPG +
Sbjct: 666 GAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPE 704



 Score =  144 bits (364), Expect = 2e-34
 Identities = 77/154 (50%), Positives = 86/154 (55%), Gaps = 6/154 (3%)

Query: 456 RGAPGPPG---PRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE---AGPVGE 509
           RG PGPPG   P G  G  G+KG  G  G  G+ G  G  G +G  G PGE    GP+G 
Sbjct: 242 RGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGP 301

Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGK 569
           RG  G RG PGL G+ G+ G  G RG  G  G  GPPG  G PGSPG  G  G  G  G 
Sbjct: 302 RGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGS 361

Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G+PGQRG  GP+G  G QGPPG PG  G PG +
Sbjct: 362 NGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGK 395



 Score =  144 bits (364), Expect = 2e-34
 Identities = 78/169 (46%), Positives = 85/169 (50%), Gaps = 24/169 (14%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP---LGPQGPQGQPGEAGPVGERGPV 513
            G PGPPGP G  G  G  GP G  G  G PG  GP    G  G +G PG  GP G  GP+
Sbjct: 888  GNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPL 947

Query: 514  GPRGFPGLKGSKGSFGTGGPRGQPGP---KGDIGPPGPEGPPGSPGPSGPQGKPGIA--- 567
            G  G  G +G  G  G  GPRG PGP   KG+ G PG  G  G  GP GPQG PG+A   
Sbjct: 948  GIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTA 1007

Query: 568  ---------------GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
                           G+ GSPG +G  G  G PG  G PG PGPPGP G
Sbjct: 1008 GEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVG 1056



 Score =  144 bits (363), Expect = 2e-34
 Identities = 75/163 (46%), Positives = 85/163 (52%), Gaps = 18/163 (11%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGG------RGPKGDPGSLGPLGPQGPQGQPGEAGPVGER 510
            G  GPPGP+G KG+ G  G  G       RG  G PGS G  GP GP G PG+ GP G  
Sbjct: 849  GPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPA 908

Query: 511  GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP------------EGPPGSPGPS 558
            G  G  G PG+ G KG  G  G +G PG +G  G PGP             GPPG PGP 
Sbjct: 909  GNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPR 968

Query: 559  GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  G  G+ G++G PG  G  G +G PG QG PGL G  G PG
Sbjct: 969  GSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPG 1011



 Score =  144 bits (362), Expect = 3e-34
 Identities = 79/158 (50%), Positives = 87/158 (55%), Gaps = 18/158 (11%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLG---------PLGPQGPQGQPGEAGP 506
           RGAPGP GPRG  G+ G  G  GG G +G PGS G         P G QG  G+PG  GP
Sbjct: 509 RGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGP 568

Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566
            G RG  G  GFPG KG+ G+ G  G RG P      G PGP+GPPG  G +GPQG PG 
Sbjct: 569 SGPRGQPGVMGFPGPKGNDGAPGKNGERGGP------GGPGPQGPPGKNGETGPQGPPGP 622

Query: 567 AGKTGSPGQRGAMGP---KGEPGIQGPPGLPGPPGPPG 601
            G  G  G  G  GP   +G PG  GPPG  G PG PG
Sbjct: 623 TGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPG 660



 Score =  143 bits (361), Expect = 4e-34
 Identities = 74/170 (43%), Positives = 89/170 (52%), Gaps = 24/170 (14%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE------- 509
           G PGPPGP G  G  G  G  G +GP G+PG  GP GP GP G  G +GP G+       
Sbjct: 177 GPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRP 236

Query: 510 --------------RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP 555
                         +GP G  GFPG+KG +G  G  G +G+ G  G  G  G  G  G+P
Sbjct: 237 GRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAP 296

Query: 556 GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
           GP GP+G P   G+ G PG  GA G +G  G +G  G PGPPGPPG+  F
Sbjct: 297 GPMGPRGAP---GERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGF 343



 Score =  143 bits (361), Expect = 4e-34
 Identities = 77/163 (47%), Positives = 88/163 (53%), Gaps = 15/163 (9%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP------VGE 509
            +G+PG  GP G  G +G+ G  G RG  G PG  GP G  GPQG  GE+G        GE
Sbjct: 932  KGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGE 991

Query: 510  RGPVGPRGFPGL---------KGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGP 560
            RGP GP+G PGL          G+ GS G  G  G PG KGD G  G  G PG+PG  GP
Sbjct: 992  RGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGP 1051

Query: 561  QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
             G  G AGK+G  G+ G  GP G PG  G  G PGP GP G +
Sbjct: 1052 PGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDK 1094



 Score =  142 bits (357), Expect = 1e-33
 Identities = 74/156 (47%), Positives = 83/156 (53%), Gaps = 9/156 (5%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            RG+PG PG  GF G  G+ GP G  G  G PG  G  G  GP G  G  G  G  G  GP
Sbjct: 863  RGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGP 922

Query: 516  RGFPGLKGSKGSFGTGGPRGQPGP---------KGDIGPPGPEGPPGSPGPSGPQGKPGI 566
            +G  G  G KGS G  GP G PGP         +G  GPPG  GP GSPGP G +G+ G 
Sbjct: 923  KGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGK 982

Query: 567  AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
             G  G  G+RG  GP+G PG+ G  G PG  G PGS
Sbjct: 983  PGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGS 1018



 Score =  140 bits (354), Expect = 3e-33
 Identities = 72/147 (48%), Positives = 82/147 (55%), Gaps = 3/147 (2%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            L G  G PG +G +G+ G  G  G  G  G PG +GP G  G +G+ G AGP G  GP G
Sbjct: 1021 LPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAG 1080

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574
             RG PG +G +G  G  G RG  G KG  G PG  G PGSPGP+G Q   G  G  G  G
Sbjct: 1081 SRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQ---GAIGSPGPAG 1137

Query: 575  QRGAMGPKGEPGIQGPPGLPGPPGPPG 601
             RG +GP G PG  G  G PGP GPPG
Sbjct: 1138 PRGPVGPSGPPGKDGTSGHPGPIGPPG 1164



 Score =  140 bits (354), Expect = 3e-33
 Identities = 72/151 (47%), Positives = 83/151 (54%), Gaps = 6/151 (3%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGP---QGQPGEAGPVGERGPV 513
            G+PG PG  G  G  G  GP G  G +G+ G  GP G  GP   +G PG  GP G++G  
Sbjct: 1038 GSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGET 1097

Query: 514  GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
            G RG  G+KG +G  G  G  G PGP G  G  G  GP G  GP GP G PG  G +G P
Sbjct: 1098 GERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHP 1157

Query: 574  GQRGAMGP---KGEPGIQGPPGLPGPPGPPG 601
            G  G  GP   +GE G +G PG PG PGPPG
Sbjct: 1158 GPIGPPGPRGNRGERGSEGSPGHPGQPGPPG 1188



 Score =  139 bits (351), Expect = 6e-33
 Identities = 79/170 (46%), Positives = 83/170 (48%), Gaps = 21/170 (12%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            L G PG PGPRG  G  GVKG  G  G  G  G  GP GPQG  G  G AG  G  G  G
Sbjct: 958  LAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPG 1017

Query: 515  PRGFPGLKGS---------KGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPG 565
              G PG  GS          GS G  G  G PGP G +GP G  G  G  GP+GP G PG
Sbjct: 1018 SDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPG 1077

Query: 566  IAGKTGSP------------GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
             AG  G+P            G+RGA G KG  G  G PG PG PGP G Q
Sbjct: 1078 PAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQ 1127



 Score =  139 bits (350), Expect = 8e-33
 Identities = 72/154 (46%), Positives = 83/154 (53%), Gaps = 9/154 (5%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           GAPG  G  G +G  G +GP G  G  G PG  G +GP G  G PG  G  G  GP G  
Sbjct: 363 GAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGAN 422

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP---------GSPGPSGPQGKPGIA 567
           G PGL+G  G  G  G +G+PGP+G+ G  G  G P         GSPG  G  G PG A
Sbjct: 423 GAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAA 482

Query: 568 GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           G+ G+PG RG  GP G PG +GP G  G PGP G
Sbjct: 483 GERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAG 516



 Score =  138 bits (348), Expect = 1e-32
 Identities = 82/184 (44%), Positives = 91/184 (49%), Gaps = 39/184 (21%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP------------------LGPQGPQ 498
           GA G PGPRG +G+ G+ G  G +G  G  GS G                    GP GP 
Sbjct: 438 GAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPN 497

Query: 499 GQPGEAGPVGERG---PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS- 554
           G PGE GP GERG   P GPRG  G  G  G  G  G RG PG  G  G  G  GPPGS 
Sbjct: 498 GIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQ 557

Query: 555 --------PGPSGPQGKPGI------AGKTGSPGQRGAMGPKGEPGIQGPPGL---PGPP 597
                   PGPSGP+G+PG+       G  G+PG+ G  G  G PG QGPPG     GP 
Sbjct: 558 GESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQ 617

Query: 598 GPPG 601
           GPPG
Sbjct: 618 GPPG 621



 Score =  138 bits (348), Expect = 1e-32
 Identities = 79/173 (45%), Positives = 87/173 (50%), Gaps = 27/173 (15%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG-------- 508
            G PG  G  G KGD G  G  G  G  G PG  GP+GP G  G  GE+GP G        
Sbjct: 1020 GLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPA 1079

Query: 509  -ERGPVGP------------RGFPGLKGSKGSFGTGGPRGQPGP---KGDIGPPGPEGPP 552
              RG  GP            RG  G+KG +G  G  G  G PGP   +G IG PGP GP 
Sbjct: 1080 GSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPR 1139

Query: 553  GSPGPSGPQGKPGIA---GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
            G  GPSGP GK G +   G  G PG RG  G +G  G  G PG PGPPGPPG+
Sbjct: 1140 GPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGA 1192



 Score =  137 bits (346), Expect = 2e-32
 Identities = 74/152 (48%), Positives = 83/152 (54%), Gaps = 9/152 (5%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGR------GPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509
           +G PGP GP G KGD G  GP G +      GP G+ G  G  GP+G  G PG  G  G+
Sbjct: 617 QGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGD 676

Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGK 569
            G  G RG PGL G+ G  G  GP   PGP+G  G  GP GPPG+ G  G QG PG  G 
Sbjct: 677 AGAPGERGPPGLAGAPGLRGGAGP---PGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGG 733

Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            GSPG +G  G  G PG  G PG  GP GP G
Sbjct: 734 LGSPGPKGDKGEPGGPGADGVPGKDGPRGPTG 765



 Score =  137 bits (345), Expect = 3e-32
 Identities = 78/186 (41%), Positives = 91/186 (48%), Gaps = 39/186 (20%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           +G  GPPGP+G +G  G  GP G  G  G+PG  G  G  G  G  G+AG  GERGP G 
Sbjct: 629 KGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGL 688

Query: 516 RGFPGLK---------GSKGSFGTGGP------------------RGQPGPKGDIGPP-- 546
            G PGL+         G KG+ G  GP                   G PGPKGD G P  
Sbjct: 689 AGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGG 748

Query: 547 ----------GPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGP 596
                     GP GP G  GP GP G+PG  G+ G+PG  G  GP+G PG +G  G PGP
Sbjct: 749 PGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGP 808

Query: 597 PGPPGS 602
            G PG+
Sbjct: 809 AGFPGA 814



 Score =  135 bits (341), Expect = 8e-32
 Identities = 77/164 (46%), Positives = 85/164 (51%), Gaps = 18/164 (10%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPVGERGPV 513
           G PG  G RGF G  G KG  G  G KG+   PG  G  GP GP+G PGE G  G  G  
Sbjct: 258 GFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAA 317

Query: 514 GPRGFPGLKGSKGSFGTGGPRG------QPGPKGDIGP---------PGPEGPPGSPGPS 558
           G RG  G +GS G  G  GP G       PG KG++GP         PG  G PG  G +
Sbjct: 318 GARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHA 377

Query: 559 GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           G QG PG  G  GSPG +G MGP G PG  G  G  GPPGP G+
Sbjct: 378 GAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGA 421



 Score =  135 bits (340), Expect = 1e-31
 Identities = 78/170 (45%), Positives = 89/170 (52%), Gaps = 29/170 (17%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLG-----PQGPQGQP--------- 501
           +G PGPPG  G  GD G+ G        G PGS GP G     P GPQ            
Sbjct: 108 KGDPGPPGIPGRNGDPGIPGQ------PGSPGSPGPPGICESCPTGPQNYSPQYDSYDVK 161

Query: 502 ------GEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP 555
                 G AG  G  GP GP G PG  G  GS G+ G +G PG  G  GP GP GPPG+ 
Sbjct: 162 SGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAI 221

Query: 556 GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
           GPSGP GK G +G+ G PG+RG  GP   PGI+GP G+PG PG  G + F
Sbjct: 222 GPSGPAGKDGESGRPGRPGERGLPGP---PGIKGPAGIPGFPGMKGHRGF 268



 Score =  135 bits (340), Expect = 1e-31
 Identities = 76/161 (47%), Positives = 83/161 (51%), Gaps = 15/161 (9%)

Query: 456 RGAPGP---PGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
           RG  GP   PG +G  G+ G  GP G RG  G+PG  G  G  G +G PG  G  G  G 
Sbjct: 491 RGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGK 550

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQ------PGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566
            GP G  G  G  G  G  GPRGQ      PGPKG+ G PG  G  G PG  GPQG PG 
Sbjct: 551 PGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGK 610

Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPP------GLPGPPGPPG 601
            G+TG  G  G  GP G+ G  GPP      GLPG  GPPG
Sbjct: 611 NGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPG 651



 Score =  135 bits (339), Expect = 1e-31
 Identities = 71/147 (48%), Positives = 77/147 (52%), Gaps = 3/147 (2%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
           LRG  G PG  G KG+    GP G RG  G PG  G  G  G  G PGE G  G  G  G
Sbjct: 427 LRGGAGEPGKNGAKGE---PGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAG 483

Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574
            RG PG +G  G  G  G +G  G +G  GP GP G  G PG  G  G PG+ G  GSPG
Sbjct: 484 ERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPG 543

Query: 575 QRGAMGPKGEPGIQGPPGLPGPPGPPG 601
             G+ G  G PG QG  G PGPPGP G
Sbjct: 544 GPGSDGKPGPPGSQGESGRPGPPGPSG 570



 Score =  134 bits (338), Expect = 2e-31
 Identities = 80/171 (46%), Positives = 84/171 (49%), Gaps = 24/171 (14%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG----- 511
           G+PG PG  G  G  G +G  G RGP G  G  G  GP G +G PG AGP G  G     
Sbjct: 468 GSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRD 527

Query: 512 --PVGP--RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPG------PSGPQ 561
             P GP  RG PG  G  GS G  GP G  G  G  GPPGP GP G PG      P G  
Sbjct: 528 GVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGND 587

Query: 562 GKPGIAGKTGSPGQRGAMGP---KGEPGIQGPPGLPGP------PGPPGSQ 603
           G PG  G+ G PG  G  GP    GE G QGPPG  GP       GPPG Q
Sbjct: 588 GAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQ 638



 Score =  134 bits (337), Expect = 2e-31
 Identities = 78/180 (43%), Positives = 91/180 (50%), Gaps = 33/180 (18%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQG------------QPGEA 504
           GA GPPGP G  G  G KG +G  G  G PG +G  GP GP G            +PG+ 
Sbjct: 378 GAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKN 437

Query: 505 GPVGERGPVGPRG---FPGLKGSKGSFGTGGPRGQPGPKG------------DIGPPGPE 549
           G  GE GP G RG    PG+ G+KG  G  G  G+PG  G              GP GP 
Sbjct: 438 GAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPN 497

Query: 550 GPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPG------PPGPPGSQ 603
           G PG  GP+G +G PG AG  G+ G+ G  G  G PG++G PG PG       PGPPGSQ
Sbjct: 498 GIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQ 557



 Score =  133 bits (335), Expect = 4e-31
 Identities = 72/148 (48%), Positives = 81/148 (54%), Gaps = 9/148 (6%)

Query: 457 GAPGPPGPRGFKGDMG---VKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPV 513
           GAPGP GPRG  G+ G   + G  G RG  G  GS G  GP GP G  G  G  G +G V
Sbjct: 294 GAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEV 353

Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
           GP G PG  G+ G       RG+PGP+G  G  GP GPPG  G  G +G+ G AG  G+P
Sbjct: 354 GPAGSPGSNGAPGQ------RGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAP 407

Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           G  GA GP G  G  G PGL G  G PG
Sbjct: 408 GLMGARGPPGPAGANGAPGLRGGAGEPG 435



 Score =  130 bits (327), Expect = 3e-30
 Identities = 74/162 (45%), Positives = 86/162 (53%), Gaps = 15/162 (9%)

Query: 456 RGAPGPPGPRGFKGDMGVKGP---------VGGRGPKGDPGSLGPLGPQGPQGQPGEAGP 506
           +G PGPPG  G  G  G  GP         +G RGP G  G+ G  G +G  G+PG+ G 
Sbjct: 380 QGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGA 439

Query: 507 VGERGPVGPR---GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGK 563
            GE GP G R   G PG+ G+KG  G  G  G+PG  G  G  G  G PG  GP+GP G 
Sbjct: 440 KGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGI 499

Query: 564 P---GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           P   G AG+ G+PG  G  G  GEPG  G PG PG  G PGS
Sbjct: 500 PGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGS 541



 Score =  121 bits (303), Expect = 2e-27
 Identities = 67/133 (50%), Positives = 74/133 (55%), Gaps = 7/133 (5%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPV---GGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
            RGAPGP GPRG KG+ G +G     G RG  G+PG+ G  GP G QG  G  GP G RGP
Sbjct: 1082 RGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGP 1141

Query: 513  VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGK-TG 571
            VGP G PG  G+ G     GP G PGP+G+ G  G EG PG PG  GP G PG  G   G
Sbjct: 1142 VGPSGPPGKDGTSGH---PGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCG 1198

Query: 572  SPGQRGAMGPKGE 584
              G     G  GE
Sbjct: 1199 GVGAAAIAGIGGE 1211



 Score =  101 bits (252), Expect = 2e-21
 Identities = 58/143 (40%), Positives = 65/143 (45%), Gaps = 23/143 (16%)

Query: 482 PKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKG 541
           P G+  ++ P  P  P   P   GP G +G  GP G PG  G  G  G  G  G PGP G
Sbjct: 80  PFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPG 139

Query: 542 --DIGPPGPE---------------------GPPGSPGPSGPQGKPGIAGKTGSPGQRGA 578
             +  P GP+                     G PG  GP GP G PG +G  GSPG  G 
Sbjct: 140 ICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGY 199

Query: 579 MGPKGEPGIQGPPGLPGPPGPPG 601
            GP GEPG  GP G PGPPG  G
Sbjct: 200 QGPPGEPGQAGPSGPPGPPGAIG 222



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 23/58 (39%), Positives = 24/58 (41%), Gaps = 18/58 (31%)

Query: 545 PPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           P  P  PP   GP GP+G PG                   PGI G  G PG PG PGS
Sbjct: 92  PTAPTRPPNGQGPQGPKGDPG------------------PPGIPGRNGDPGIPGQPGS 131


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score =  157 bits (396), Expect = 3e-38
 Identities = 78/161 (48%), Positives = 92/161 (57%), Gaps = 15/161 (9%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G PGPPGP G  G  G +G  G  G  G+PG  GP GP G +G+PG+ GP G  GP GP+
Sbjct: 915  GPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQ 974

Query: 517  GF---------PGLKGSKGSFGTGGPRGQPGPKG------DIGPPGPEGPPGSPGPSGPQ 561
            G          PG +G +G  G  GP G+PG +G      D GPPGP GPPG  GP+G  
Sbjct: 975  GLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEP 1034

Query: 562  GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
            G+ G  G  G PG+ GA G KG+ G  G  G PG PGPPGS
Sbjct: 1035 GREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS 1075



 Score =  156 bits (395), Expect = 5e-38
 Identities = 79/145 (54%), Positives = 84/145 (57%), Gaps = 3/145 (2%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G+PGP GP G +GD G  G  G  GP G  G+ G  GPQGP+G  GEAG  GERG  G R
Sbjct: 1074 GSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHR 1133

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
            GF GL+G  G     GP G  G  G  GP GP GPPG  GPSG  G  GI G  G PG R
Sbjct: 1134 GFTGLQGLPGP---PGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPR 1190

Query: 577  GAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  G  G  G  G PG PGPPGPPG
Sbjct: 1191 GRSGETGPAGPPGNPGPPGPPGPPG 1215



 Score =  152 bits (384), Expect = 9e-37
 Identities = 76/152 (50%), Positives = 84/152 (55%), Gaps = 6/152 (3%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLG---PQGPQGQPGEAGPVGERGP 512
           RG  GPPGP GF G  G  G  G +G +G+ G  G  G   PQGP G PG  GP G  GP
Sbjct: 824 RGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGP 883

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572
            G RG  G  G+ G  G  G  G PG  G+ GPPGP GP G  GP G +G  G  G+ G 
Sbjct: 884 KGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 943

Query: 573 PGQRGAMGP---KGEPGIQGPPGLPGPPGPPG 601
           PG +G  GP   KGEPG  GP G  GPPGP G
Sbjct: 944 PGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQG 975



 Score =  151 bits (381), Expect = 2e-36
 Identities = 80/167 (47%), Positives = 90/167 (53%), Gaps = 21/167 (12%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG------- 508
           RGA G  GP+G +GD+G KGP G  G  G  G  GP+GP GP G  GE G VG       
Sbjct: 755 RGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGS 814

Query: 509 -----------ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP 557
                      E GP GP GF G  G+ G  G  G +G+ G KGD G PGP+GP G+PGP
Sbjct: 815 AGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGP 874

Query: 558 SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGL---PGPPGPPG 601
            GP G  G  G  G+ G  GA G  G  G  GPPG    PGPPGPPG
Sbjct: 875 QGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 921



 Score =  150 bits (380), Expect = 2e-36
 Identities = 81/154 (52%), Positives = 88/154 (57%), Gaps = 9/154 (5%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PGP GP G +G+ G  GP G +G  G PG  G  G  G QG PGEAG  G  GP G R
Sbjct: 642 GPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGER 701

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGP---PGPEGPPGSPGPSGPQGKP------GIA 567
           GFPG +GS G+ G  GPRG PG  G  GP    GP GPPG+ GP G QG P      GIA
Sbjct: 702 GFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIA 761

Query: 568 GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           G  G  G  G  GP+G PG  G  GL GP GPPG
Sbjct: 762 GPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPG 795



 Score =  149 bits (377), Expect = 6e-36
 Identities = 74/147 (50%), Positives = 84/147 (57%), Gaps = 6/147 (4%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           GAPG  G  G  G+ G  GP+G RG  G+ G  GP G  G +G  G+ GP G  GPVGP 
Sbjct: 303 GAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPA 362

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           G PG  G+ G+ G  GP G  GP+G  GP G  G PGSPGP+G  G PG  G  G+ G  
Sbjct: 363 GGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSA 422

Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           GA      PGI G PG PGP GPPG Q
Sbjct: 423 GA------PGIAGAPGFPGPRGPPGPQ 443



 Score =  149 bits (377), Expect = 6e-36
 Identities = 79/151 (52%), Positives = 85/151 (56%), Gaps = 9/151 (5%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            GAPG PGP    G  G  GP G +G +G+ G+ GP+GP GP G  G  GP G RG  G  
Sbjct: 1065 GAPGAPGP---PGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEA 1121

Query: 517  GFP---GLKGSKGSFGTGGPRGQPGPKGD---IGPPGPEGPPGSPGPSGPQGKPGIAGKT 570
            G P   GLKG +G  G  G  G PGP GD    GP GP GP G PGP GP GK G  G  
Sbjct: 1122 GEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIP 1181

Query: 571  GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  G  G  G  GE G  GPPG PGPPGPPG
Sbjct: 1182 GPIGPPGPRGRSGETGPAGPPGNPGPPGPPG 1212



 Score =  147 bits (372), Expect = 2e-35
 Identities = 84/174 (48%), Positives = 88/174 (50%), Gaps = 27/174 (15%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGG---RGPKGDPGSLGPLGPQGPQGQPG---------EA 504
           G+PGP GPRG  G+ G  GP G    RG  G PG  GP GP GP G PG         EA
Sbjct: 318 GSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEA 377

Query: 505 GPVGERGPVG---PRGFPGLKGSKGSFGTGGPRGQ---PGPKGDIGPPGPEGPPGSPGPS 558
           GP G RGP G   PRG PG  GS G  G  G  G    PG KG  G PG  G PG PGP 
Sbjct: 378 GPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPR 437

Query: 559 GPQGKPGIAGKTGSPGQ---------RGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           GP G  G  G  G  GQ         +G  GPKGEPG  GP G PGP G  G +
Sbjct: 438 GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKR 491



 Score =  147 bits (371), Expect = 3e-35
 Identities = 75/151 (49%), Positives = 82/151 (54%), Gaps = 6/151 (3%)

Query: 457 GAPGPPGPRGFKGDMGV------KGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGER 510
           G PG PGP G  G+ G       KG  G  G  G PG  GP GP GPQG  G  GP G+ 
Sbjct: 396 GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQT 455

Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKT 570
           G  G  GF G +G KG  G  GP+G PGP G+ G  G  G PG  GP GP G+ G  G  
Sbjct: 456 GEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNR 515

Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           G PGQ G  GPKG PG +GP GL GP G  G
Sbjct: 516 GFPGQDGLAGPKGAPGERGPSGLAGPKGANG 546



 Score =  147 bits (370), Expect = 4e-35
 Identities = 73/147 (49%), Positives = 82/147 (55%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           RG PGP G RGF G  G+ G  G RG  G  G+ G  G  G +G+ G  G  G  GP+GP
Sbjct: 266 RGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP 325

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
           RG PG +G  G  G  G RG  G  G  GPPGP GP G PG  G  G  G AG TG+ G 
Sbjct: 326 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 385

Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPGS 602
            GA GP+GEPG  G PG  G  G PG+
Sbjct: 386 EGAQGPRGEPGTPGSPGPAGASGNPGT 412



 Score =  147 bits (370), Expect = 4e-35
 Identities = 83/186 (44%), Positives = 93/186 (50%), Gaps = 39/186 (20%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            GA GPPGP+G  G  G+ G  G RG +G PG  GP G  G QG PG +G  G  GPVGP 
Sbjct: 966  GAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPP 1025

Query: 517  GF------PGLKGSKGSFGTGGPRGQPGPKGD------IGPPGPEGPPGSPGPSGPQGKP 564
            G       PG +GS G+ G  G  G  G KGD      +G PG  GPPGSPGP+GP GK 
Sbjct: 1026 GLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQ 1085

Query: 565  GIAGKTGSPGQRGAMGPKGEPGIQGP---------------------------PGLPGPP 597
            G  G+ G+ G  G  GP G  GIQGP                            GLPGPP
Sbjct: 1086 GDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPP 1145

Query: 598  GPPGSQ 603
            GP G Q
Sbjct: 1146 GPSGDQ 1151



 Score =  146 bits (369), Expect = 5e-35
 Identities = 76/170 (44%), Positives = 88/170 (51%), Gaps = 21/170 (12%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP-------- 506
           + GAPG PGPRG  G  G  GP+G +G  G+PG  G  G QGP+G+PG AGP        
Sbjct: 427 IAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAG 486

Query: 507 -------------VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPG 553
                        VG  GP G RG PG +G  G  G  GP+G PG +G  G  GP+G  G
Sbjct: 487 EEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANG 546

Query: 554 SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            PG  G  G PG  G TG PG  G  G  G  G  G  G PGPPGP G++
Sbjct: 547 DPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGAR 596



 Score =  145 bits (365), Expect = 1e-34
 Identities = 74/151 (49%), Positives = 82/151 (54%), Gaps = 6/151 (3%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            GAPGP GP G  G  G +G  G  G  G PG+ G +GP G  G PG  GP G  G  GP+
Sbjct: 870  GAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPK 929

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
            G  G  G  G  G  G +G  GP G+ G PG +GP G+ GP GPQG  G  G  G PGQR
Sbjct: 930  GARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQR 989

Query: 577  GAM------GPKGEPGIQGPPGLPGPPGPPG 601
            G        GP GEPG QG PG  G  GPPG
Sbjct: 990  GERGFPGLPGPSGEPGKQGAPGASGDRGPPG 1020



 Score =  144 bits (363), Expect = 2e-34
 Identities = 72/151 (47%), Positives = 86/151 (56%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
           L+G PG  G  G  G  G +G VG +GP+G PG  G  G  GP G PG AG  GE+G VG
Sbjct: 748 LQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVG 807

Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574
           P G  G  G++G+ G  G  G PGP G  GPPG +G PG+ G  G  G+ G AG  G  G
Sbjct: 808 PPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQG 867

Query: 575 QRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
             GA GP+G  G+ GP G  G  GPPG+  F
Sbjct: 868 PSGAPGPQGPTGVTGPKGARGAQGPPGATGF 898



 Score =  143 bits (361), Expect = 4e-34
 Identities = 77/159 (48%), Positives = 92/159 (57%), Gaps = 12/159 (7%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV---GERGP 512
           +G  G PG  GFKG+ G KG  G  GP+G PG  G  G +G +G+PG  GP+   GERG 
Sbjct: 452 KGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGA 511

Query: 513 VGPRGFP---GLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA-- 567
            G RGFP   GL G KG+ G  GP G  GPKG  G PG  G PG PG  G  G+PG A  
Sbjct: 512 PGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGP 571

Query: 568 ----GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
               G +G+PG+ G  GP G  G +G PG+ G PGP G+
Sbjct: 572 QGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGA 610



 Score =  142 bits (358), Expect = 9e-34
 Identities = 77/161 (47%), Positives = 88/161 (54%), Gaps = 15/161 (9%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE---AGPVGERGPV 513
           GA G  GPRG  G  G  GP G  GP G PG+ GP G QG  G+ G    AGP G+RG V
Sbjct: 711 GAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV 770

Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGP------KGDIGPPGP------EGPPGSPGPSGPQ 561
           G +G  G  G  G  G  GP G PGP      KG++GPPGP       G PG  G +GP 
Sbjct: 771 GEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPP 830

Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           G  G AG  G+ GQ GA G +GE G +G  G PGP GP G+
Sbjct: 831 GPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGA 871



 Score =  142 bits (358), Expect = 9e-34
 Identities = 70/150 (46%), Positives = 84/150 (56%), Gaps = 3/150 (2%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           GA GPPG +G  G+ G  G  G +G +GD G  GP G  G  G  G  GP+G  GP G  
Sbjct: 741 GAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGAN 800

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEG---PPGSPGPSGPQGKPGIAGKTGSP 573
           G  G  G  G  G+ G RG PG +G+ GPPGP G   PPG+ G  G +G+ G AG+ G  
Sbjct: 801 GEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDA 860

Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           G  G  GP G PG QGP G+ GP G  G+Q
Sbjct: 861 GAPGPQGPSGAPGPQGPTGVTGPKGARGAQ 890



 Score =  141 bits (356), Expect = 2e-33
 Identities = 77/161 (47%), Positives = 91/161 (56%), Gaps = 18/161 (11%)

Query: 456 RGAPGP---PGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
           RG PGP   PGP+GF+G+ G  G  G  GP G  G  GP G  G  G+ G+ G  GERGP
Sbjct: 209 RGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGP 268

Query: 513 VGPRG---------FPGLKGSKGSFGTGGPRGQ---PGPKGDIGPPGPEGPPGSPGPSGP 560
            GP+G          PG+KG +G  G  G +G+   PG KG+ G PG     GSPGP GP
Sbjct: 269 PGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN---GSPGPMGP 325

Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           +G PG  G+TG  G  GA G  G+PG  GPPG  GP G PG
Sbjct: 326 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPG 366



 Score =  140 bits (352), Expect = 4e-33
 Identities = 77/167 (46%), Positives = 91/167 (54%), Gaps = 18/167 (10%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQ---PGEAGPVGERGPV 513
           G  GPPGP G  G  G  G  G +G  G  G+ GP G QGP+G+   PG  GP G  G  
Sbjct: 351 GPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNP 410

Query: 514 GPRGFPGLKGSKGSFGTG------GPRGQPGPKGDIGPPGPEGPPGSP------GPSGPQ 561
           G  G PG KGS G+ G        GPRG PGP+G  GP GP+G  G P      G  GP+
Sbjct: 411 GTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPK 470

Query: 562 GKPGIAGKTGSP---GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
           G+PG AG  G+P   G+ G  G +GEPG  GP G PG  G PG++ F
Sbjct: 471 GEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGF 517



 Score =  139 bits (351), Expect = 6e-33
 Identities = 75/159 (47%), Positives = 84/159 (52%), Gaps = 12/159 (7%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKG---DPGSLGPLGPQGPQGQPGEAGPVGERGPV 513
           G  GP G RGF G+ G  G  G +GP+G    PG+ GP G  GP G PG  GP G +G  
Sbjct: 693 GLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMP 752

Query: 514 GPRGFPGL---KGSKGSFGTGGPRGQPGP------KGDIGPPGPEGPPGSPGPSGPQGKP 564
           G RG  G+   KG +G  G  GP G PG        G IGPPGP G  G  G  GP G  
Sbjct: 753 GERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPA 812

Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           G AG  G+PG+RG  GP G  G  GPPG  G PG  G Q
Sbjct: 813 GSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQ 851



 Score =  139 bits (350), Expect = 8e-33
 Identities = 73/159 (45%), Positives = 89/159 (55%), Gaps = 12/159 (7%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQG------QPGEAGPVGER 510
           G PGPPGP+G +G  GV G  G +G  G+PG  G  G  G  G      + GE G  G  
Sbjct: 585 GRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPP 644

Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPG---SPGPSGPQGKPGIA 567
           GP GP G  G +G+ G  G  G  G PGP G+ G PG +G PG   +PG  GP+G+ G  
Sbjct: 645 GPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFP 704

Query: 568 GKTGSPGQRGAMGPK---GEPGIQGPPGLPGPPGPPGSQ 603
           G+ GSPG +G  GP+   G PG  GP G  GP GPPG+Q
Sbjct: 705 GERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQ 743



 Score =  137 bits (346), Expect = 2e-32
 Identities = 79/175 (45%), Positives = 86/175 (49%), Gaps = 30/175 (17%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G  GPPG RG  G+ G  G  G  GPKG PG  GP G  GP+G  G+ G  GE G  G R
Sbjct: 501 GPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR 560

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPG------PSGPQGKPGIAGK- 569
           G  G  G  G  G  GP G PG  G  GPPGP+G  G PG      P G  G+PG AG+ 
Sbjct: 561 GLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEK 620

Query: 570 --TGSPGQRGAMGPKGEPGIQGPP---------------------GLPGPPGPPG 601
              G+PG RG  G  GE G  GPP                     GLPGPPGPPG
Sbjct: 621 GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPG 675



 Score =  137 bits (344), Expect = 4e-32
 Identities = 73/153 (47%), Positives = 86/153 (56%), Gaps = 12/153 (7%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG------EAGPVGER 510
           G PG  G  G  G  G  G  G RGP G  G+ GPLGP+G  G+PG      E GP GE 
Sbjct: 414 GIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 473

Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKT 570
           GP GP+G PG  G +G     G RG+PG  G IGPPG  G PG+    G  G+ G+AG  
Sbjct: 474 GPAGPQGAPGPAGEEGK---RGARGEPGGVGPIGPPGERGAPGN---RGFPGQDGLAGPK 527

Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           G+PG+RG  G  G  G  G PG PG PG PG++
Sbjct: 528 GAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR 560



 Score =  136 bits (343), Expect = 5e-32
 Identities = 76/172 (44%), Positives = 93/172 (54%), Gaps = 27/172 (15%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG-- 514
           G PG PG +G  G  G +GP G +GP+G+PG+ G  GP G  G PG  G  G +G  G  
Sbjct: 366 GFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAP 425

Query: 515 ----------PRGFPGLKGSKGSFGTGGPRGQPGP---KGDIGP---PGPEGPPGSPGPS 558
                     PRG PG +G+ G  G  G  G+PG    KG+ GP   PGP GP G+PGP+
Sbjct: 426 GIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA 485

Query: 559 GPQGK------PGIAGKTGSPGQRGAMGPKGEP---GIQGPPGLPGPPGPPG 601
           G +GK      PG  G  G PG+RGA G +G P   G+ GP G PG  GP G
Sbjct: 486 GEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSG 537



 Score =  136 bits (343), Expect = 5e-32
 Identities = 73/157 (46%), Positives = 80/157 (50%), Gaps = 9/157 (5%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVG---------GRGPKGDPGSLGPLGPQGPQGQPGEAGP 506
           +GAPG  GP G  G  G  G  G          RG  G PG  GP G  GP G PGE G 
Sbjct: 527 KGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGR 586

Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566
            G  GP G RG PG+ G  G  G  G  G+ G KG  G PG  G PG  G +G  G PG 
Sbjct: 587 PGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP 646

Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           AG  G  G++GA GP G  G+ GPPG PG  G PG Q
Sbjct: 647 AGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQ 683



 Score =  135 bits (341), Expect = 8e-32
 Identities = 74/152 (48%), Positives = 80/152 (52%), Gaps = 3/152 (1%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PG PG RG  G  G  GP G  GP G PG  G  GP GPQG  G+ G +G  GP G  
Sbjct: 552 GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 611

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           G PG  G KG  G  G RG PG  G+ G  GP GP G  G  G QG PG +G  G PG  
Sbjct: 612 GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP 671

Query: 577 GAMGPKGEPGIQGPPGLPGPP---GPPGSQSF 605
           G  G  G+PG QG PG  G P   GP G + F
Sbjct: 672 GPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 703



 Score =  135 bits (340), Expect = 1e-31
 Identities = 76/188 (40%), Positives = 93/188 (49%), Gaps = 33/188 (17%)

Query: 449 LRNVTILRGAPGPPGP------RGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG 502
           ++++   +G PGP GP      RG +GD G KG  G RG  G+PG+ G  GP GP G PG
Sbjct: 112 IKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPG 171

Query: 503 E---------------------------AGPVGERGPVGPRGFPGLKGSKGSFGTGGPRG 535
                                        GP+G  GP GP G  G  G +G  G  G  G
Sbjct: 172 PPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG 231

Query: 536 QPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPG 595
           +PG  G +GP GP GPPG PG  G  GKPG AG+ G PG +GA G  G PG+ G  G  G
Sbjct: 232 EPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRG 291

Query: 596 PPGPPGSQ 603
            PG  G++
Sbjct: 292 YPGLDGAK 299



 Score =  135 bits (339), Expect = 1e-31
 Identities = 72/160 (45%), Positives = 87/160 (54%), Gaps = 15/160 (9%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G  G  GP G  G+ G  GP G +G +G PG +G  GP+G  G+PG+AG  G  G  G R
Sbjct: 570 GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLR 629

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           G PG  G  G+ G  GP G  G +G+ G PGP G  G PGP GP G+ G  G  G PG+ 
Sbjct: 630 GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA 689

Query: 577 GA---MGPKGE------------PGIQGPPGLPGPPGPPG 601
           GA   +GP+GE             G+QGP GLPG PG  G
Sbjct: 690 GAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDG 729



 Score =  133 bits (334), Expect = 5e-31
 Identities = 77/195 (39%), Positives = 91/195 (46%), Gaps = 46/195 (23%)

Query: 457 GAPGPPGPRGFKGDM----------GVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP 506
           G PGP G +G  GD+          G +GP G +GP+GD G  G  G  GP+G+ GE G 
Sbjct: 98  GQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT 157

Query: 507 VGERGPVGPRGFPGLKGSKGSF------------------------GTGGPRGQPGPKGD 542
            G  GP GP G PG  G  G+F                        G  GPRG PGP G 
Sbjct: 158 PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGA 217

Query: 543 IGPPGPEGPPGSPG------------PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGP 590
            GP G +G PG PG            P GP GKPG  G+ G PG+ G  GP G  G +G 
Sbjct: 218 PGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGF 277

Query: 591 PGLPGPPGPPGSQSF 605
           PG PG PG  G + +
Sbjct: 278 PGTPGLPGVKGHRGY 292



 Score =  132 bits (333), Expect = 7e-31
 Identities = 73/158 (46%), Positives = 88/158 (55%), Gaps = 12/158 (7%)

Query: 456 RGAPGP---PGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQ---GPQGQPGEAGPVGE 509
           +GAPGP    G RG +G+ G  GP+G  G +G PG+ G  G     GP+G PGE GP G 
Sbjct: 479 QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGL 538

Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQP---GPKGDIGP---PGPEGPPGSPGPSGPQGK 563
            GP G  G PG  G  G  G  G  G+P   GP+G +GP   PG +G PG PGP G +G+
Sbjct: 539 AGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ 598

Query: 564 PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           PG+ G  G  G  G  G  GE G+ G PGL G PG  G
Sbjct: 599 PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDG 636



 Score =  102 bits (253), Expect = 1e-21
 Identities = 63/169 (37%), Positives = 72/169 (42%), Gaps = 49/169 (28%)

Query: 482 PKGDPGSLGPLGPQGPQGQPGEAGPVGERGPV-------------------GPRGFPGLK 522
           P G+   + P       GQPG  G  GE G +                   GPRG  G K
Sbjct: 81  PFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDK 140

Query: 523 GSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP--------------------------- 555
           G KG+ G  G  G+PG  G+ GPPGP GPPG P                           
Sbjct: 141 GEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQ 200

Query: 556 ---GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
              GP GP+G PG AG  G  G +G  G  GEPG+ GP G  GPPGPPG
Sbjct: 201 GPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPG 249



 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 51/114 (44%), Positives = 56/114 (49%), Gaps = 15/114 (13%)

Query: 450  RNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509
            R  T L+G PGPPGP    GD G  GP G  GP+G PG      P GP G+ G  G  G 
Sbjct: 1133 RGFTGLQGLPGPPGP---SGDQGASGPAGPSGPRGPPG------PVGPSGKDGANGIPGP 1183

Query: 510  RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGK 563
             GP GPR      G  G  G  GP G PGP G  GPPGP     +    GP+ K
Sbjct: 1184 IGPPGPR------GRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREK 1231



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 30/91 (32%), Positives = 34/91 (37%), Gaps = 37/91 (40%)

Query: 548 PEGPPGSPGPSGPQGKPGIAGKTGSPGQRG-------AMGPKGEPGIQGP---------- 590
           PE P G   P  P      +G+ G  GQ+G        +GPKG PG QGP          
Sbjct: 78  PEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDR 137

Query: 591 --------------------PGLPGPPGPPG 601
                               PG PGPPGPPG
Sbjct: 138 GDKGEKGAPGPRGRDGEPGTPGNPGPPGPPG 168


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score =  157 bits (396), Expect = 3e-38
 Identities = 78/161 (48%), Positives = 92/161 (57%), Gaps = 15/161 (9%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G PGPPGP G  G  G +G  G  G  G+PG  GP GP G +G+PG+ GP G  GP GP+
Sbjct: 846  GPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQ 905

Query: 517  GF---------PGLKGSKGSFGTGGPRGQPGPKG------DIGPPGPEGPPGSPGPSGPQ 561
            G          PG +G +G  G  GP G+PG +G      D GPPGP GPPG  GP+G  
Sbjct: 906  GLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEP 965

Query: 562  GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
            G+ G  G  G PG+ GA G KG+ G  G  G PG PGPPGS
Sbjct: 966  GREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS 1006



 Score =  156 bits (395), Expect = 5e-38
 Identities = 79/145 (54%), Positives = 84/145 (57%), Gaps = 3/145 (2%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G+PGP GP G +GD G  G  G  GP G  G+ G  GPQGP+G  GEAG  GERG  G R
Sbjct: 1005 GSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHR 1064

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
            GF GL+G  G     GP G  G  G  GP GP GPPG  GPSG  G  GI G  G PG R
Sbjct: 1065 GFTGLQGLPGP---PGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPR 1121

Query: 577  GAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  G  G  G  G PG PGPPGPPG
Sbjct: 1122 GRSGETGPAGPPGNPGPPGPPGPPG 1146



 Score =  152 bits (384), Expect = 9e-37
 Identities = 76/152 (50%), Positives = 84/152 (55%), Gaps = 6/152 (3%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLG---PQGPQGQPGEAGPVGERGP 512
           RG  GPPGP GF G  G  G  G +G +G+ G  G  G   PQGP G PG  GP G  GP
Sbjct: 755 RGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGP 814

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572
            G RG  G  G+ G  G  G  G PG  G+ GPPGP GP G  GP G +G  G  G+ G 
Sbjct: 815 KGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 874

Query: 573 PGQRGAMGP---KGEPGIQGPPGLPGPPGPPG 601
           PG +G  GP   KGEPG  GP G  GPPGP G
Sbjct: 875 PGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQG 906



 Score =  151 bits (381), Expect = 2e-36
 Identities = 80/167 (47%), Positives = 90/167 (53%), Gaps = 21/167 (12%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV-------- 507
           RGA G  GP+G +GD+G KGP G  G  G  G  GP+GP GP G  GE G V        
Sbjct: 686 RGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGS 745

Query: 508 ----------GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP 557
                     GE GP GP GF G  G+ G  G  G +G+ G KGD G PGP+GP G+PGP
Sbjct: 746 AGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGP 805

Query: 558 SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGL---PGPPGPPG 601
            GP G  G  G  G+ G  GA G  G  G  GPPG    PGPPGPPG
Sbjct: 806 QGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 852



 Score =  150 bits (380), Expect = 2e-36
 Identities = 81/154 (52%), Positives = 88/154 (57%), Gaps = 9/154 (5%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PGP GP G +G+ G  GP G +G  G PG  G  G  G QG PGEAG  G  GP G R
Sbjct: 573 GPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGER 632

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGP---PGPEGPPGSPGPSGPQGKP------GIA 567
           GFPG +GS G+ G  GPRG PG  G  GP    GP GPPG+ GP G QG P      GIA
Sbjct: 633 GFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIA 692

Query: 568 GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           G  G  G  G  GP+G PG  G  GL GP GPPG
Sbjct: 693 GPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPG 726



 Score =  149 bits (377), Expect = 6e-36
 Identities = 74/147 (50%), Positives = 84/147 (57%), Gaps = 6/147 (4%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           GAPG  G  G  G+ G  GP+G RG  G+ G  GP G  G +G  G+ GP G  GPVGP 
Sbjct: 234 GAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPA 293

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           G PG  G+ G+ G  GP G  GP+G  GP G  G PGSPGP+G  G PG  G  G+ G  
Sbjct: 294 GGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSA 353

Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           GA      PGI G PG PGP GPPG Q
Sbjct: 354 GA------PGIAGAPGFPGPRGPPGPQ 374



 Score =  149 bits (377), Expect = 6e-36
 Identities = 79/151 (52%), Positives = 85/151 (56%), Gaps = 9/151 (5%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            GAPG PGP    G  G  GP G +G +G+ G+ GP+GP GP G  G  GP G RG  G  
Sbjct: 996  GAPGAPGP---PGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEA 1052

Query: 517  GFP---GLKGSKGSFGTGGPRGQPGPKGD---IGPPGPEGPPGSPGPSGPQGKPGIAGKT 570
            G P   GLKG +G  G  G  G PGP GD    GP GP GP G PGP GP GK G  G  
Sbjct: 1053 GEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIP 1112

Query: 571  GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  G  G  G  GE G  GPPG PGPPGPPG
Sbjct: 1113 GPIGPPGPRGRSGETGPAGPPGNPGPPGPPG 1143



 Score =  147 bits (372), Expect = 2e-35
 Identities = 84/174 (48%), Positives = 88/174 (50%), Gaps = 27/174 (15%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGG---RGPKGDPGSLGPLGPQGPQGQPG---------EA 504
           G+PGP GPRG  G+ G  GP G    RG  G PG  GP GP GP G PG         EA
Sbjct: 249 GSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEA 308

Query: 505 GPVGERGPVG---PRGFPGLKGSKGSFGTGGPRGQ---PGPKGDIGPPGPEGPPGSPGPS 558
           GP G RGP G   PRG PG  GS G  G  G  G    PG KG  G PG  G PG PGP 
Sbjct: 309 GPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPR 368

Query: 559 GPQGKPGIAGKTGSPGQ---------RGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           GP G  G  G  G  GQ         +G  GPKGEPG  GP G PGP G  G +
Sbjct: 369 GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKR 422



 Score =  147 bits (371), Expect = 3e-35
 Identities = 75/151 (49%), Positives = 82/151 (54%), Gaps = 6/151 (3%)

Query: 457 GAPGPPGPRGFKGDMGV------KGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGER 510
           G PG PGP G  G+ G       KG  G  G  G PG  GP GP GPQG  G  GP G+ 
Sbjct: 327 GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQT 386

Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKT 570
           G  G  GF G +G KG  G  GP+G PGP G+ G  G  G PG  GP GP G+ G  G  
Sbjct: 387 GEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNR 446

Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           G PGQ G  GPKG PG +GP GL GP G  G
Sbjct: 447 GFPGQDGLAGPKGAPGERGPSGLAGPKGANG 477



 Score =  147 bits (370), Expect = 4e-35
 Identities = 73/147 (49%), Positives = 82/147 (55%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           RG PGP G RGF G  G+ G  G RG  G  G+ G  G  G +G+ G  G  G  GP+GP
Sbjct: 197 RGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP 256

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
           RG PG +G  G  G  G RG  G  G  GPPGP GP G PG  G  G  G AG TG+ G 
Sbjct: 257 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 316

Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPGS 602
            GA GP+GEPG  G PG  G  G PG+
Sbjct: 317 EGAQGPRGEPGTPGSPGPAGASGNPGT 343



 Score =  147 bits (370), Expect = 4e-35
 Identities = 83/186 (44%), Positives = 93/186 (50%), Gaps = 39/186 (20%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            GA GPPGP+G  G  G+ G  G RG +G PG  GP G  G QG PG +G  G  GPVGP 
Sbjct: 897  GAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPP 956

Query: 517  GF------PGLKGSKGSFGTGGPRGQPGPKGD------IGPPGPEGPPGSPGPSGPQGKP 564
            G       PG +GS G+ G  G  G  G KGD      +G PG  GPPGSPGP+GP GK 
Sbjct: 957  GLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQ 1016

Query: 565  GIAGKTGSPGQRGAMGPKGEPGIQGP---------------------------PGLPGPP 597
            G  G+ G+ G  G  GP G  GIQGP                            GLPGPP
Sbjct: 1017 GDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPP 1076

Query: 598  GPPGSQ 603
            GP G Q
Sbjct: 1077 GPSGDQ 1082



 Score =  146 bits (369), Expect = 5e-35
 Identities = 76/170 (44%), Positives = 88/170 (51%), Gaps = 21/170 (12%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP-------- 506
           + GAPG PGPRG  G  G  GP+G +G  G+PG  G  G QGP+G+PG AGP        
Sbjct: 358 IAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAG 417

Query: 507 -------------VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPG 553
                        VG  GP G RG PG +G  G  G  GP+G PG +G  G  GP+G  G
Sbjct: 418 EEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANG 477

Query: 554 SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            PG  G  G PG  G TG PG  G  G  G  G  G  G PGPPGP G++
Sbjct: 478 DPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGAR 527



 Score =  145 bits (365), Expect = 1e-34
 Identities = 74/151 (49%), Positives = 82/151 (54%), Gaps = 6/151 (3%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           GAPGP GP G  G  G +G  G  G  G PG+ G +GP G  G PG  GP G  G  GP+
Sbjct: 801 GAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPK 860

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           G  G  G  G  G  G +G  GP G+ G PG +GP G+ GP GPQG  G  G  G PGQR
Sbjct: 861 GARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQR 920

Query: 577 GAM------GPKGEPGIQGPPGLPGPPGPPG 601
           G        GP GEPG QG PG  G  GPPG
Sbjct: 921 GERGFPGLPGPSGEPGKQGAPGASGDRGPPG 951



 Score =  144 bits (363), Expect = 2e-34
 Identities = 72/151 (47%), Positives = 86/151 (56%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
           L+G PG  G  G  G  G +G VG +GP+G PG  G  G  GP G PG AG  GE+G VG
Sbjct: 679 LQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVG 738

Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574
           P G  G  G++G+ G  G  G PGP G  GPPG +G PG+ G  G  G+ G AG  G  G
Sbjct: 739 PPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQG 798

Query: 575 QRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
             GA GP+G  G+ GP G  G  GPPG+  F
Sbjct: 799 PSGAPGPQGPTGVTGPKGARGAQGPPGATGF 829



 Score =  143 bits (361), Expect = 4e-34
 Identities = 77/159 (48%), Positives = 92/159 (57%), Gaps = 12/159 (7%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV---GERGP 512
           +G  G PG  GFKG+ G KG  G  GP+G PG  G  G +G +G+PG  GP+   GERG 
Sbjct: 383 KGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGA 442

Query: 513 VGPRGFP---GLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA-- 567
            G RGFP   GL G KG+ G  GP G  GPKG  G PG  G PG PG  G  G+PG A  
Sbjct: 443 PGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGP 502

Query: 568 ----GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
               G +G+PG+ G  GP G  G +G PG+ G PGP G+
Sbjct: 503 QGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGA 541



 Score =  142 bits (358), Expect = 9e-34
 Identities = 77/161 (47%), Positives = 88/161 (54%), Gaps = 15/161 (9%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE---AGPVGERGPV 513
           GA G  GPRG  G  G  GP G  GP G PG+ GP G QG  G+ G    AGP G+RG V
Sbjct: 642 GAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV 701

Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGP------KGDIGPPGP------EGPPGSPGPSGPQ 561
           G +G  G  G  G  G  GP G PGP      KG++GPPGP       G PG  G +GP 
Sbjct: 702 GEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPP 761

Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           G  G AG  G+ GQ GA G +GE G +G  G PGP GP G+
Sbjct: 762 GPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGA 802



 Score =  142 bits (358), Expect = 9e-34
 Identities = 70/150 (46%), Positives = 84/150 (56%), Gaps = 3/150 (2%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           GA GPPG +G  G+ G  G  G +G +GD G  GP G  G  G  G  GP+G  GP G  
Sbjct: 672 GAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGAN 731

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEG---PPGSPGPSGPQGKPGIAGKTGSP 573
           G  G  G  G  G+ G RG PG +G+ GPPGP G   PPG+ G  G +G+ G AG+ G  
Sbjct: 732 GEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDA 791

Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           G  G  GP G PG QGP G+ GP G  G+Q
Sbjct: 792 GAPGPQGPSGAPGPQGPTGVTGPKGARGAQ 821



 Score =  141 bits (356), Expect = 2e-33
 Identities = 77/161 (47%), Positives = 91/161 (56%), Gaps = 18/161 (11%)

Query: 456 RGAPGP---PGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
           RG PGP   PGP+GF+G+ G  G  G  GP G  G  GP G  G  G+ G+ G  GERGP
Sbjct: 140 RGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGP 199

Query: 513 VGPRG---------FPGLKGSKGSFGTGGPRGQ---PGPKGDIGPPGPEGPPGSPGPSGP 560
            GP+G          PG+KG +G  G  G +G+   PG KG+ G PG     GSPGP GP
Sbjct: 200 PGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN---GSPGPMGP 256

Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           +G PG  G+TG  G  GA G  G+PG  GPPG  GP G PG
Sbjct: 257 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPG 297



 Score =  140 bits (353), Expect = 3e-33
 Identities = 74/172 (43%), Positives = 87/172 (50%), Gaps = 18/172 (10%)

Query: 450 RNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509
           R +T   G PGP G  G KG++G  GP G  G +G PG  G  GP GP G  G  G  G+
Sbjct: 716 RGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQ 775

Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGK 569
            G  G +G  G KG  G+ G  GP G PGP+G  G  GP+G  G+ GP G  G PG AG+
Sbjct: 776 PGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGR 835

Query: 570 TGSPGQ------------------RGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G PG                   +GA G  G PG  G PGL GP GPPG +
Sbjct: 836 VGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEK 887



 Score =  140 bits (352), Expect = 4e-33
 Identities = 77/167 (46%), Positives = 91/167 (54%), Gaps = 18/167 (10%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQ---PGEAGPVGERGPV 513
           G  GPPGP G  G  G  G  G +G  G  G+ GP G QGP+G+   PG  GP G  G  
Sbjct: 282 GPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNP 341

Query: 514 GPRGFPGLKGSKGSFGTG------GPRGQPGPKGDIGPPGPEGPPGSP------GPSGPQ 561
           G  G PG KGS G+ G        GPRG PGP+G  GP GP+G  G P      G  GP+
Sbjct: 342 GTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPK 401

Query: 562 GKPGIAGKTGSP---GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
           G+PG AG  G+P   G+ G  G +GEPG  GP G PG  G PG++ F
Sbjct: 402 GEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGF 448



 Score =  139 bits (351), Expect = 6e-33
 Identities = 75/159 (47%), Positives = 84/159 (52%), Gaps = 12/159 (7%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKG---DPGSLGPLGPQGPQGQPGEAGPVGERGPV 513
           G  GP G RGF G+ G  G  G +GP+G    PG+ GP G  GP G PG  GP G +G  
Sbjct: 624 GLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMP 683

Query: 514 GPRGFPGL---KGSKGSFGTGGPRGQPGP------KGDIGPPGPEGPPGSPGPSGPQGKP 564
           G RG  G+   KG +G  G  GP G PG        G IGPPGP G  G  G  GP G  
Sbjct: 684 GERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPA 743

Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           G AG  G+PG+RG  GP G  G  GPPG  G PG  G Q
Sbjct: 744 GSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQ 782



 Score =  139 bits (350), Expect = 8e-33
 Identities = 73/159 (45%), Positives = 89/159 (55%), Gaps = 12/159 (7%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQG------QPGEAGPVGER 510
           G PGPPGP+G +G  GV G  G +G  G+PG  G  G  G  G      + GE G  G  
Sbjct: 516 GRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPP 575

Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPG---SPGPSGPQGKPGIA 567
           GP GP G  G +G+ G  G  G  G PGP G+ G PG +G PG   +PG  GP+G+ G  
Sbjct: 576 GPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFP 635

Query: 568 GKTGSPGQRGAMGPK---GEPGIQGPPGLPGPPGPPGSQ 603
           G+ GSPG +G  GP+   G PG  GP G  GP GPPG+Q
Sbjct: 636 GERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQ 674



 Score =  137 bits (346), Expect = 2e-32
 Identities = 79/175 (45%), Positives = 86/175 (49%), Gaps = 30/175 (17%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G  GPPG RG  G+ G  G  G  GPKG PG  GP G  GP+G  G+ G  GE G  G R
Sbjct: 432 GPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR 491

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPG------PSGPQGKPGIAGK- 569
           G  G  G  G  G  GP G PG  G  GPPGP+G  G PG      P G  G+PG AG+ 
Sbjct: 492 GLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEK 551

Query: 570 --TGSPGQRGAMGPKGEPGIQGPP---------------------GLPGPPGPPG 601
              G+PG RG  G  GE G  GPP                     GLPGPPGPPG
Sbjct: 552 GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPG 606



 Score =  137 bits (344), Expect = 4e-32
 Identities = 73/153 (47%), Positives = 86/153 (56%), Gaps = 12/153 (7%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG------EAGPVGER 510
           G PG  G  G  G  G  G  G RGP G  G+ GPLGP+G  G+PG      E GP GE 
Sbjct: 345 GIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 404

Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKT 570
           GP GP+G PG  G +G     G RG+PG  G IGPPG  G PG+    G  G+ G+AG  
Sbjct: 405 GPAGPQGAPGPAGEEGK---RGARGEPGGVGPIGPPGERGAPGN---RGFPGQDGLAGPK 458

Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           G+PG+RG  G  G  G  G PG PG PG PG++
Sbjct: 459 GAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR 491



 Score =  136 bits (343), Expect = 5e-32
 Identities = 76/172 (44%), Positives = 93/172 (54%), Gaps = 27/172 (15%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG-- 514
           G PG PG +G  G  G +GP G +GP+G+PG+ G  GP G  G PG  G  G +G  G  
Sbjct: 297 GFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAP 356

Query: 515 ----------PRGFPGLKGSKGSFGTGGPRGQPGP---KGDIGP---PGPEGPPGSPGPS 558
                     PRG PG +G+ G  G  G  G+PG    KG+ GP   PGP GP G+PGP+
Sbjct: 357 GIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA 416

Query: 559 GPQGK------PGIAGKTGSPGQRGAMGPKGEP---GIQGPPGLPGPPGPPG 601
           G +GK      PG  G  G PG+RGA G +G P   G+ GP G PG  GP G
Sbjct: 417 GEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSG 468



 Score =  136 bits (343), Expect = 5e-32
 Identities = 73/157 (46%), Positives = 80/157 (50%), Gaps = 9/157 (5%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVG---------GRGPKGDPGSLGPLGPQGPQGQPGEAGP 506
           +GAPG  GP G  G  G  G  G          RG  G PG  GP G  GP G PGE G 
Sbjct: 458 KGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGR 517

Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566
            G  GP G RG PG+ G  G  G  G  G+ G KG  G PG  G PG  G +G  G PG 
Sbjct: 518 PGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP 577

Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           AG  G  G++GA GP G  G+ GPPG PG  G PG Q
Sbjct: 578 AGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQ 614



 Score =  135 bits (341), Expect = 8e-32
 Identities = 74/152 (48%), Positives = 80/152 (52%), Gaps = 3/152 (1%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PG PG RG  G  G  GP G  GP G PG  G  GP GPQG  G+ G +G  GP G  
Sbjct: 483 GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 542

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           G PG  G KG  G  G RG PG  G+ G  GP GP G  G  G QG PG +G  G PG  
Sbjct: 543 GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP 602

Query: 577 GAMGPKGEPGIQGPPGLPGPP---GPPGSQSF 605
           G  G  G+PG QG PG  G P   GP G + F
Sbjct: 603 GPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 634



 Score =  135 bits (340), Expect = 1e-31
 Identities = 76/188 (40%), Positives = 93/188 (49%), Gaps = 33/188 (17%)

Query: 449 LRNVTILRGAPGPPGP------RGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG 502
           ++++   +G PGP GP      RG +GD G KG  G RG  G+PG+ G  GP GP G PG
Sbjct: 43  IKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPG 102

Query: 503 E---------------------------AGPVGERGPVGPRGFPGLKGSKGSFGTGGPRG 535
                                        GP+G  GP GP G  G  G +G  G  G  G
Sbjct: 103 PPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG 162

Query: 536 QPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPG 595
           +PG  G +GP GP GPPG PG  G  GKPG AG+ G PG +GA G  G PG+ G  G  G
Sbjct: 163 EPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRG 222

Query: 596 PPGPPGSQ 603
            PG  G++
Sbjct: 223 YPGLDGAK 230



 Score =  135 bits (339), Expect = 1e-31
 Identities = 72/160 (45%), Positives = 87/160 (54%), Gaps = 15/160 (9%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G  G  GP G  G+ G  GP G +G +G PG +G  GP+G  G+PG+AG  G  G  G R
Sbjct: 501 GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLR 560

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           G PG  G  G+ G  GP G  G +G+ G PGP G  G PGP GP G+ G  G  G PG+ 
Sbjct: 561 GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA 620

Query: 577 GA---MGPKGE------------PGIQGPPGLPGPPGPPG 601
           GA   +GP+GE             G+QGP GLPG PG  G
Sbjct: 621 GAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDG 660



 Score =  132 bits (333), Expect = 7e-31
 Identities = 74/176 (42%), Positives = 85/176 (48%), Gaps = 30/176 (17%)

Query: 460 GPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFP 519
           GP GP G +G  G +GP G RG KG+ G+ GP G  G  G PG  GP G  GP GP G  
Sbjct: 48  GPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLG 107

Query: 520 G------------------LKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPG----- 556
           G                  L   +G  G  GPRG PGP G  GP G +G PG PG     
Sbjct: 108 GNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVS 167

Query: 557 -------PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
                  P GP GKPG  G+ G PG+ G  GP G  G +G PG PG PG  G + +
Sbjct: 168 GPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGY 223



 Score =  132 bits (333), Expect = 7e-31
 Identities = 73/158 (46%), Positives = 88/158 (55%), Gaps = 12/158 (7%)

Query: 456 RGAPGP---PGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQ---GPQGQPGEAGPVGE 509
           +GAPGP    G RG +G+ G  GP+G  G +G PG+ G  G     GP+G PGE GP G 
Sbjct: 410 QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGL 469

Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQP---GPKGDIGP---PGPEGPPGSPGPSGPQGK 563
            GP G  G PG  G  G  G  G  G+P   GP+G +GP   PG +G PG PGP G +G+
Sbjct: 470 AGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ 529

Query: 564 PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           PG+ G  G  G  G  G  GE G+ G PGL G PG  G
Sbjct: 530 PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDG 567



 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 51/114 (44%), Positives = 56/114 (49%), Gaps = 15/114 (13%)

Query: 450  RNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509
            R  T L+G PGPPGP    GD G  GP G  GP+G PG      P GP G+ G  G  G 
Sbjct: 1064 RGFTGLQGLPGPPGP---SGDQGASGPAGPSGPRGPPG------PVGPSGKDGANGIPGP 1114

Query: 510  RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGK 563
             GP GPR      G  G  G  GP G PGP G  GPPGP     +    GP+ K
Sbjct: 1115 IGPPGPR------GRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREK 1162



 Score = 88.6 bits (218), Expect = 2e-17
 Identities = 57/160 (35%), Positives = 67/160 (41%), Gaps = 65/160 (40%)

Query: 496 GPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD------------- 542
           GP+GQ GE G +  +  VGP+G PG +G         P G+ GP+GD             
Sbjct: 32  GPKGQKGEPGDI--KDIVGPKGPPGPQG---------PAGEQGPRGDRGDKGEKGAPGPR 80

Query: 543 -----------IGPPGPEGPPGSP------------------------------GPSGPQ 561
                       GPPGP GPPG P                              GP GP+
Sbjct: 81  GRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPR 140

Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           G PG AG  G  G +G  G  GEPG+ GP G  GPPGPPG
Sbjct: 141 GPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPG 180



 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 42/76 (55%), Positives = 47/76 (61%), Gaps = 10/76 (13%)

Query: 536 QPGPKGDIGPP-------GPEGPPGSPGPS---GPQGKPGIAGKTGSPGQRGAMGPKGEP 585
           QPGPKG  G P       GP+GPPG  GP+   GP+G  G  G+ G+PG RG  G  G P
Sbjct: 30  QPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTP 89

Query: 586 GIQGPPGLPGPPGPPG 601
           G  GPPG PGPPGPPG
Sbjct: 90  GNPGPPGPPGPPGPPG 105



 Score = 70.1 bits (170), Expect = 6e-12
 Identities = 33/73 (45%), Positives = 39/73 (53%), Gaps = 13/73 (17%)

Query: 542 DIGPPGPEGPPGS-------------PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQ 588
           D+  PGP+G  G              PGP GP G+ G  G  G  G++GA GP+G  G  
Sbjct: 27  DVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 86

Query: 589 GPPGLPGPPGPPG 601
           G PG PGPPGPPG
Sbjct: 87  GTPGNPGPPGPPG 99


>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
          Length = 684

 Score =  157 bits (396), Expect = 3e-38
 Identities = 85/165 (51%), Positives = 95/165 (57%), Gaps = 18/165 (10%)

Query: 457 GAPGPPGPRGFKGDMGVKGP---VGGRGPKGDPGSLGPLG---------PQGPQGQPGEA 504
           G PGPPG  GFKG  G KG    VG  G KGDPG  GP G         P+G +G PG  
Sbjct: 181 GPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPL 240

Query: 505 GPVGERGPVG---PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQ 561
           GP G+RGP+G   P G PG  G  G  G  GP G  GPKGD+G PGP+G PG  GPSG  
Sbjct: 241 GPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEP 300

Query: 562 GKPGIAGKTGSPG---QRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           G PG  G+ G PG   Q+G  G  G PG +GP GLPG PG  GS+
Sbjct: 301 GMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSK 345



 Score =  140 bits (352), Expect = 4e-33
 Identities = 76/164 (46%), Positives = 89/164 (54%), Gaps = 18/164 (10%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRG---PKGDPGSLGPLGPQGPQGQPG---------E 503
           +G PGPPGP G  G +G++GP G RG   P G PG  GP+G +GP G PG         E
Sbjct: 210 KGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGE 269

Query: 504 AGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP------GSPGP 557
            GP G RGP G  G PG KG+ G  G  G  G PG  G  G PG +G        G+PG 
Sbjct: 270 RGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGE 329

Query: 558 SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            GP G PG+ G+ GS G++G  G  GE G  GP G PG PG  G
Sbjct: 330 KGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAG 373



 Score =  139 bits (350), Expect = 8e-33
 Identities = 76/157 (48%), Positives = 86/157 (54%), Gaps = 11/157 (7%)

Query: 446 GEILRNVTILR-GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEA 504
           GE+L      R G PGPPGP G  G  G  G  G  GP G PG  GP G  G  G+PGEA
Sbjct: 17  GELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEA 76

Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564
           G  G          PG+ G  G  G  GP+G PG +G +GPPGP G  G  G  GP G+ 
Sbjct: 77  GLPG---------LPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPG-LGGKGLPGPPGEA 126

Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           G++G  G  G RG  GP G PG+ GPPG PGPPG PG
Sbjct: 127 GVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPG 163



 Score =  139 bits (349), Expect = 1e-32
 Identities = 74/159 (46%), Positives = 83/159 (52%), Gaps = 9/159 (5%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG---------EAGP 506
           +G PGPPG  G  G  G  G  G  GP G PG  GP GP GP G PG         +   
Sbjct: 117 KGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPS 176

Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566
           +   GP GP G PG KG  G  G  G  G+ G KGD GPPGP G PGS G  GP+G  G+
Sbjct: 177 ICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGL 236

Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
            G  G PG RG +G +G PGI G PG  G  G  G + F
Sbjct: 237 PGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGF 275



 Score =  137 bits (346), Expect = 2e-32
 Identities = 79/188 (42%), Positives = 95/188 (50%), Gaps = 25/188 (13%)

Query: 441 VDTQHGEILRNVTI-------LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPG------ 487
           +D Q GE  RN          L G PG  G +G KG+ G  G +G  GP G+PG      
Sbjct: 314 LDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAG 373

Query: 488 ------------SLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRG 535
                       S G LGPQGP G PG  G  G++G +G  G PG +G +G  G  GP G
Sbjct: 374 MPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGG 433

Query: 536 QPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPG 595
             GPKGD G  G +G PG  G  GP G  G  G++GS G+ G  G +G  G  G  G+PG
Sbjct: 434 AAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPG 493

Query: 596 PPGPPGSQ 603
           PPGP G Q
Sbjct: 494 PPGPLGLQ 501



 Score =  130 bits (326), Expect = 5e-30
 Identities = 75/162 (46%), Positives = 83/162 (51%), Gaps = 21/162 (12%)

Query: 455 LRGAPGPPGPRGFKGDMGVKG------------PVGGRGPKGDPGSLGPLGPQGPQGQPG 502
           L G PGPPGP G  G  GV              P G  GP G PG  GP G +G QG+ G
Sbjct: 146 LPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVG 205

Query: 503 EAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQG 562
           + G  G+ GP GP G PG      S G  GPRG  G  G +GPPG  GP G  GP G  G
Sbjct: 206 KDGEKGDPGPPGPAGLPG------SVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPG 259

Query: 563 KPGIAGKTGSPGQRGAMGPKGE---PGIQGPPGLPGPPGPPG 601
            PG AG  G  G  G  GPKG+   PG +G PG+ GP G PG
Sbjct: 260 APGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPG 301



 Score =  130 bits (326), Expect = 5e-30
 Identities = 68/145 (46%), Positives = 77/145 (53%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G  G PG RG  G  G  G +G +GP G PG  G  G +G  G PG  GP G RG VG R
Sbjct: 370 GDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDR 429

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           G  G  G KG  G  G  G PG KG++GP G  GP G  G  G  G  G  G  G+ G +
Sbjct: 430 GPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQ 489

Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPG 601
           G  GP G  G+QG PG+PG  G PG
Sbjct: 490 GVPGPPGPLGLQGVPGVPGITGKPG 514



 Score =  125 bits (314), Expect = 1e-28
 Identities = 76/189 (40%), Positives = 86/189 (45%), Gaps = 43/189 (22%)

Query: 456 RGAPGPPGPRGFKGD------------MGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE 503
           +G PG PG RGF+G              G++G VG RGP G  G  G  G  G  G PG+
Sbjct: 393 QGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGD 452

Query: 504 AGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGK 563
            G +G  G VGP+G  G +G  G  GT GP G  G +G  GPPGP G  G PG  G  GK
Sbjct: 453 KGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGK 512

Query: 564 PGIAGKTGS----------------------------PGQRGAMGPKGEPGIQGPPGL-- 593
           PG+ GK  S                            PG  G  GP G PG  GPPG   
Sbjct: 513 PGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIG 572

Query: 594 -PGPPGPPG 601
            PG  GPPG
Sbjct: 573 HPGARGPPG 581



 Score =  124 bits (311), Expect = 3e-28
 Identities = 72/163 (44%), Positives = 78/163 (47%), Gaps = 19/163 (11%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PGPPGP+G  G  G  G  G  G  G  G  G  GP GP+G PGE G +G  GP G  
Sbjct: 56  GLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLG 115

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI---------- 566
           G  GL G  G  G  GP G  G +G  GP G  G PG PGP GP G PG+          
Sbjct: 116 G-KGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQC 174

Query: 567 --------AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
                    G  G PG +G  G KGE G  G  G  G PGPPG
Sbjct: 175 PSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPG 217



 Score =  124 bits (311), Expect = 3e-28
 Identities = 82/237 (34%), Positives = 93/237 (39%), Gaps = 92/237 (38%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPG----------------------------- 487
           G PG PGP+G +GD+G +GP G  GPKGD G                             
Sbjct: 412 GDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSR 471

Query: 488 -SLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKG----------------------- 523
             LGP G QGP G  G  G  G  GP+G +G PG+ G                       
Sbjct: 472 GELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGG 531

Query: 524 --------------------SKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGK 563
                               S G  G  GP G PGP G IG PG  GPPG  GP+G  G 
Sbjct: 532 MISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGD 591

Query: 564 PGIAGKTGSPGQRGAM-----GPKGEPGIQGP--------------PGLPGPPGPPG 601
           PG  G  G  G +GA      GP+G+ G QGP              PG PGPPG PG
Sbjct: 592 PGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPG 648



 Score =  120 bits (300), Expect = 5e-27
 Identities = 68/157 (43%), Positives = 81/157 (51%), Gaps = 18/157 (11%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G  G PG  G KG+ G  G  G +GP G PG  G  G +G +G+ G AG +GE GP G  
Sbjct: 307 GQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEP 366

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           G P      G  G  G RG+ G +G  G  GP+GPPG+PG  G QG+ G  G  G PG +
Sbjct: 367 GVP------GDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQ 420

Query: 577 ------------GAMGPKGEPGIQGPPGLPGPPGPPG 601
                       GA GPKG+ GI G  GLPG  G  G
Sbjct: 421 GLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELG 457



 Score =  117 bits (294), Expect = 2e-26
 Identities = 72/180 (40%), Positives = 80/180 (44%), Gaps = 40/180 (22%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGD----------------------------- 485
           ++G PGPPGP G +G  GV G  G  G  G                              
Sbjct: 488 VQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKP 547

Query: 486 --PGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDI 543
             PGS+G  GP GP G PG  G +G  G  GP   PG +G  G  G  GPRG  G +GD 
Sbjct: 548 LAPGSIGRPGPAGPPGPPGPPGSIGHPGARGP---PGYRGPTGELGDPGPRGNQGDRGDK 604

Query: 544 GPPGP--EGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           G  G   +GP G  GP GPQG PG    T   GQ GA G  G PG  G PG  G  G PG
Sbjct: 605 GAAGAGLDGPEGDQGPQGPQGVPG----TSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660



 Score =  100 bits (248), Expect = 5e-21
 Identities = 57/132 (43%), Positives = 66/132 (50%), Gaps = 19/132 (14%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG-----PVGERG 511
           G PGPPGP G  G  G +GP G RGP G+ G  GP G QG +G  G AG     P G++G
Sbjct: 560 GPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQG 619

Query: 512 PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTG 571
           P GP+G PG               + G  G  G PGP G PG PG  G QG PGI   + 
Sbjct: 620 PQGPQGVPGTS-------------KDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSA 666

Query: 572 SPGQ-RGAMGPK 582
             G   G +G K
Sbjct: 667 CQGAVLGGVGEK 678



 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 60/131 (45%), Positives = 70/131 (53%), Gaps = 20/131 (15%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G+ G PGP G         P G  GP   PGS+G  G +GP   PG  GP GE G  GPR
Sbjct: 551 GSIGRPGPAG---------PPGPPGP---PGSIGHPGARGP---PGYRGPTGELGDPGPR 595

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           G  G +G KG+ G     G  GP+GD GP GP+G PG+    G  G PG  G  G PG  
Sbjct: 596 GNQGDRGDKGAAGA----GLDGPEGDQGPQGPQGVPGT-SKDGQDGAPGEPGPPGDPGLP 650

Query: 577 GAMGPKGEPGI 587
           GA+G +G PGI
Sbjct: 651 GAIGAQGTPGI 661



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 26/53 (49%), Positives = 27/53 (50%), Gaps = 15/53 (28%)

Query: 550 GPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           G PG PGP GP GKPG  G  G  G               PPGLPGPPGP G+
Sbjct: 29  GLPGPPGPPGPPGKPGQDGIDGEAG---------------PPGLPGPPGPKGA 66


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein
           [Homo sapiens]
          Length = 1650

 Score =  156 bits (395), Expect = 5e-38
 Identities = 79/146 (54%), Positives = 89/146 (60%), Gaps = 9/146 (6%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           RG PGPPGP    G+ G+ G  G  G KGDP   GP G  G  G  G  G  GERG  G 
Sbjct: 856 RGHPGPPGP---PGEQGLPGTAGKEGTKGDP---GPPGAPGKDGPAGLRGFPGERGLPGT 909

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
            G PGLKG++G  G  GP G PG +G  G  GP GPPG PGP GP   PG AG+ G PG+
Sbjct: 910 AGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP---PGAAGEKGVPGE 966

Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPG 601
           +G +GP G  G+QGP GLPGP GPPG
Sbjct: 967 KGPIGPTGRDGVQGPVGLPGPAGPPG 992



 Score =  150 bits (380), Expect = 2e-36
 Identities = 84/187 (44%), Positives = 96/187 (51%), Gaps = 45/187 (24%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLG------PLGPQGP------------- 497
            G PGP G RG  G  G +G  GG+G KGDPG++G      P+GP GP             
Sbjct: 1226 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLP 1285

Query: 498  -----QGQPGEAGPVGERGPVGPRGFPGLKGSKGS---------FGTGGPRGQPGPKGDI 543
                 QG+PG  G  G  GPVGP G PGL+G  G+          G  GP G+ G KGD 
Sbjct: 1286 GSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDR 1345

Query: 544  GPPGPEGPPGSP------------GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPP 591
            G PGP+G PG              GP GP G PG AG  G+ G  G  GPKGE G+QGPP
Sbjct: 1346 GLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPP 1405

Query: 592  GLPGPPG 598
            G PGPPG
Sbjct: 1406 GHPGPPG 1412



 Score =  149 bits (376), Expect = 7e-36
 Identities = 85/174 (48%), Positives = 99/174 (56%), Gaps = 27/174 (15%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVG--GR-GPKGD---PGSLGPLGPQGPQGQPGEAGPVGER 510
           G PGPPG  G KG +GV G  G  GR GPKG    PG  G  G +G +G  G++GP GER
Sbjct: 695 GDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER 754

Query: 511 GPVGPRGFPGLKGS---KGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA 567
           GP GPRG  G +G+    G+ GT G  G  GP G+ G PGP+GP G PGP GP G PG  
Sbjct: 755 GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKD 814

Query: 568 GKTGSPGQRGAMGPKGEPGIQGPPGL------------------PGPPGPPGSQ 603
           G  G PGQRG +G +G+ G  GPPG+                  PGPPGPPG Q
Sbjct: 815 GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ 868



 Score =  149 bits (375), Expect = 9e-36
 Identities = 82/171 (47%), Positives = 95/171 (55%), Gaps = 24/171 (14%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGG------RGPKGDPGSLGPLGPQGPQGQPGEAGPVGER 510
            G PGP GP G  G+ G KG VG       +G KG+ G  GP GP GP GQPG AG  GE 
Sbjct: 983  GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEP 1042

Query: 511  GPVGPRGFPGLKGSKGSFGTGGP------RGQPGPKG------DIGPPGPEGPPGSPGPS 558
            G  GP+G  G KG +G+ G  GP      +G PGP G      D+GP GP GPPG  GP+
Sbjct: 1043 GARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPA 1102

Query: 559  ------GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
                  GPQG PG  G  G PG++G  G  G PGIQG PG+ GP G  G +
Sbjct: 1103 GPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEK 1153



 Score =  148 bits (373), Expect = 2e-35
 Identities = 72/148 (48%), Positives = 84/148 (56%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            L+G PGP G +G  GD+G  GP G  GP+G  G  G  GPQGP G  G  GP GE+G  G
Sbjct: 1071 LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1130

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574
              G PG++G  G  G  G RG+ G  G  G PGP GP G  G  GP+G PG  G  G PG
Sbjct: 1131 ESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPG 1190

Query: 575  QRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
              G  GP+G+ G +G  G  G PG PGS
Sbjct: 1191 PPGEGGPRGQDGAKGDRGEDGEPGQPGS 1218



 Score =  147 bits (372), Expect = 2e-35
 Identities = 79/152 (51%), Positives = 89/152 (58%), Gaps = 12/152 (7%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            +G PG  G  G +G+ GVKGP G RG KG+ G  G  GP GP+G  G+ GP G  GPVG 
Sbjct: 1126 KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG- 1184

Query: 516  RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS------GPQGKPGIAGK 569
              FPG  G  G    GGPRGQ G KGD G  G  G PGSPGP+      GP GK G AG 
Sbjct: 1185 --FPGDPGPPGE---GGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1239

Query: 570  TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
             GS G++G  G KG+PG  G PG  GP GP G
Sbjct: 1240 PGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAG 1271



 Score =  145 bits (367), Expect = 8e-35
 Identities = 75/153 (49%), Positives = 90/153 (58%), Gaps = 9/153 (5%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PG PG +G +GD G +G  G   P G+ G  G  G  GP+G PGE+GP G  GP GP 
Sbjct: 476 GLPGLPGEKGHRGDTGAQGLPG---PPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPP 532

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS---PGPS---GPQGKPGIAGKT 570
           G PG  G +G  G  GP+G  GP+G+ GPPG +G PG+   PGP    GP G+ G  GK 
Sbjct: 533 GIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKP 592

Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           G PG  G+ GP G PG +GPPG  G  GP G Q
Sbjct: 593 GLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQ 625



 Score =  145 bits (367), Expect = 8e-35
 Identities = 76/150 (50%), Positives = 86/150 (57%), Gaps = 9/150 (6%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG---ERGPV 513
            G PGPPGPRG        GP G  GP+G PG +G LGP G +G+PGE+G  G   E G  
Sbjct: 1091 GPPGPPGPRG------PAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVK 1144

Query: 514  GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
            GPRG  G KG  G  G  GP G  GP GD GP G  GP G PG  GP G+ G  G+ G+ 
Sbjct: 1145 GPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAK 1204

Query: 574  GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G RG  G  G+PG  GP G  GPPGP G +
Sbjct: 1205 GDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1234



 Score =  145 bits (366), Expect = 1e-34
 Identities = 81/160 (50%), Positives = 88/160 (55%), Gaps = 12/160 (7%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP--- 512
           RG  G  G RG  GD GVKG  G  G  G PG  G  G  G QG PG  G  GERG    
Sbjct: 451 RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGE 510

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSG---PQGKPGIAGK 569
           +GPRG PG  G +G  G  GP G PGP G  G  GP+GP GS GP G   P G+ G  G 
Sbjct: 511 IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT 570

Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPG------PPGPPGSQ 603
            G PG +GA+GP GE G QG PGLPG      PPG PG +
Sbjct: 571 QGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKE 610



 Score =  145 bits (366), Expect = 1e-34
 Identities = 76/152 (50%), Positives = 89/152 (58%), Gaps = 9/152 (5%)

Query: 457  GAPGPPGP---RGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPV 513
            GAPG  GP   RGF G+ G+ G  GG G KG+ G   P GP GP G PGE G  G  GP+
Sbjct: 887  GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEG---PSGPPGPAGSPGERGAAGSGGPI 943

Query: 514  GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQG---KPGIAGKT 570
            GP G PG +G  G+ G  G  G+ GP G  G  G +GP G PGP+GP G   + G  G+ 
Sbjct: 944  GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 1003

Query: 571  GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
            G PGQ+G  G KGE G  GPPG  GP G PG+
Sbjct: 1004 GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1035



 Score =  144 bits (363), Expect = 2e-34
 Identities = 76/160 (47%), Positives = 89/160 (55%), Gaps = 18/160 (11%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            GA G PG RG +G  G KG  G RG  G PG +G  G  GP G+ GE G VG  GP GP 
Sbjct: 1037 GADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP- 1095

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI---------A 567
              PG +G  G  G  GP+G PG  G++GPPG +G PG  G  G QG+PG+          
Sbjct: 1096 --PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEK 1153

Query: 568  GKTGSPGQRGAMGPKGEPGIQGPPGLPGP------PGPPG 601
            G++G PG+ G  GPKG  G  GP G PGP      PGPPG
Sbjct: 1154 GESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG 1193



 Score =  142 bits (359), Expect = 7e-34
 Identities = 77/167 (46%), Positives = 91/167 (54%), Gaps = 18/167 (10%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGPVG 508
            L G  G PG +G +G  G  GP G  G +G  GS GP+GP      QGP G  GE G  G
Sbjct: 906  LPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPG 965

Query: 509  ERGPVGPRGFPGLKGSKGSFGTGGP---RGQPGPKGDIGPPGPE---------GPPGSPG 556
            E+GP+GP G  G++G  G  G  GP    G+ G KG++G PG +         GPPG PG
Sbjct: 966  EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG 1025

Query: 557  PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            P GP G+PG AG  G PG RG  G  G  G +G  G  GPPGP G Q
Sbjct: 1026 PIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ 1072



 Score =  142 bits (359), Expect = 7e-34
 Identities = 74/150 (49%), Positives = 88/150 (58%), Gaps = 6/150 (4%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G PG PG  G  G+ G  GP+G RGP G PGS G  G +G +G PG  G  G+ GPVGP 
Sbjct: 1211 GEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPA 1270

Query: 517  G---FPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
            G    PG  G +G  G+ G +G+PG  G  GPPGP GPPG PG    +G  G  G+ G P
Sbjct: 1271 GPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGL---RGDAGAKGEKGHP 1327

Query: 574  GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G  G +GP GE G +G  GLPGP G PG +
Sbjct: 1328 GLIGLIGPPGEQGEKGDRGLPGPQGSPGQK 1357



 Score =  141 bits (356), Expect = 2e-33
 Identities = 77/152 (50%), Positives = 86/152 (56%), Gaps = 9/152 (5%)

Query: 460 GPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQ---GQPGEAGPVGERGPVGPR 516
           GPPGP G+ G  G  G  G  G KG+ G LGP GP+GPQ   G PG+AG  G  G  G R
Sbjct: 401 GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGAR 460

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ- 575
           G PG  G KG  G  G  G PG KG  G  G +G PG PG  G +G  G  G  G PG+ 
Sbjct: 461 GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 520

Query: 576 --RGAMGPKGEPGIQGPP---GLPGPPGPPGS 602
             RG +GPKG PGI GPP   G+ GP GP GS
Sbjct: 521 GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGS 552



 Score =  140 bits (353), Expect = 3e-33
 Identities = 81/167 (48%), Positives = 87/167 (52%), Gaps = 21/167 (12%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGP--- 506
            RGA G  GP G  G  G +GP G  G KG PG  GP+GP      QGP G PG AGP   
Sbjct: 934  RGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGV 993

Query: 507  VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566
             GE G  G  G PG KG+KG+ G  GP G PGP G +G PG  G  G PG  GPQG  G 
Sbjct: 994  AGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGA 1053

Query: 567  AGKTGSPGQRGAMGP------------KGEPGIQGPPGLPGPPGPPG 601
             G  G+ G  G  GP            KGE G  GP G PGPPGP G
Sbjct: 1054 KGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG 1100



 Score =  140 bits (353), Expect = 3e-33
 Identities = 78/165 (47%), Positives = 86/165 (52%), Gaps = 21/165 (12%)

Query: 457  GAPGPPGPRGFKGDMGVKG------------PVGGRGPKGDPGSLGPLGPQGPQGQPGEA 504
            G PGPPGP+G  GD G KG            P G  GP+G  G+ G  G  G  GQPG  
Sbjct: 1160 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSP 1219

Query: 505  GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG------PEGPPGSPGPS 558
            GP GE GP GP G  G  GS GS G  G +G  G  G IG PG      P GP G PGP 
Sbjct: 1220 GPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPD 1279

Query: 559  GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G +G PG  G+ G PG  G  GP   PG  GPPGLPG  G  G++
Sbjct: 1280 GLRGLPGSVGQQGRPGATGQAGP---PGPVGPPGLPGLRGDAGAK 1321



 Score =  140 bits (352), Expect = 4e-33
 Identities = 76/174 (43%), Positives = 86/174 (49%), Gaps = 27/174 (15%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PGPPG RG  G  G KG +G +G  G PG  G  G QG  G  G  GP GE+GP G  
Sbjct: 533 GIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKP 592

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI---------- 566
           G PG+ GS G  G  G  G PG KG+ GP GP+GP G PGP G +G  GI          
Sbjct: 593 GLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEK 652

Query: 567 -----------------AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
                             G+ G PG RG  GP+G  G  GP G PGPPG  G +
Sbjct: 653 GEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEK 706



 Score =  140 bits (352), Expect = 4e-33
 Identities = 79/173 (45%), Positives = 84/173 (48%), Gaps = 27/173 (15%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G  G  GPRG  G  G KG  GG GP G PG  G  GPQGP G PG  GP G  G  G  
Sbjct: 758 GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLP 817

Query: 517 GFPGLKGSKGSFGTGGPRGQP------------GPKGDIGPPGPEGPP------------ 552
           G PG +G  G  G  GP G P            GP G+ G PGP GPP            
Sbjct: 818 GHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKE 877

Query: 553 ---GSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
              G PGP G  GK G AG  G PG+RG  G  G PG++G  G  GPPGP GS
Sbjct: 878 GTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGS 930



 Score =  138 bits (348), Expect = 1e-32
 Identities = 78/174 (44%), Positives = 91/174 (52%), Gaps = 24/174 (13%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGG------RGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509
           +G PGPPG +G  G  G+ GP G       +GP+G PG  G  G  GP G PG+ GP G 
Sbjct: 556 QGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGT 615

Query: 510 RG------PVGPRGFP---------GLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP--- 551
           +G      P GP G+P         G++G KG  G  G  G PG KGDIG  G  G    
Sbjct: 616 KGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV 675

Query: 552 PGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
           PGS G  GP+G  G  G TG PG  G MG KG+ G+ G PG PG  GP GS  F
Sbjct: 676 PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGF 729



 Score =  137 bits (346), Expect = 2e-32
 Identities = 79/166 (47%), Positives = 88/166 (53%), Gaps = 18/166 (10%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG---------EAGP 506
            +G PG  GP G  G  GV+GPVG  GP G PG  G  G +G  G PG         E GP
Sbjct: 961  KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 1020

Query: 507  VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD------IGPPGPEGPPGSPGPSGP 560
             G  GP+GP G PG  G+ G  G  GP+G  G KGD       GPPGP G  G PGPSG 
Sbjct: 1021 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1080

Query: 561  QGKPGIA---GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            +G+ G     G  G PG RG  GP G  G QGPPG  G  GPPG +
Sbjct: 1081 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEK 1126



 Score =  137 bits (345), Expect = 3e-32
 Identities = 76/155 (49%), Positives = 84/155 (54%), Gaps = 15/155 (9%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           RG  G  GPRG +G  G +G  G RG  G  G+ G  G  GP G PGE G  G   P GP
Sbjct: 742 RGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPG---PQGP 798

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
            GFPG KG  G  G  G  G PG +G++G  G  GPPG PG  GPQ   G AG+TG  G+
Sbjct: 799 NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ---GAAGETGPMGE 855

Query: 576 RGAMGPKGEPGIQGPPGL---------PGPPGPPG 601
           RG  GP G PG QG PG          PGPPG PG
Sbjct: 856 RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG 890



 Score =  136 bits (342), Expect = 6e-32
 Identities = 74/171 (43%), Positives = 87/171 (50%), Gaps = 15/171 (8%)

Query: 450 RNVTILRGAPGPPG------------PRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGP 497
           R  T  +G PGPPG            PRG  G+ G +G +G +GP G PG  G  G  GP
Sbjct: 487 RGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGP 546

Query: 498 QGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD---IGPPGPEGPPGS 554
           QG  G  GP GE GP G +G PG +G  G  G  GP G+ GP+G     G PG +GPPG 
Sbjct: 547 QGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 606

Query: 555 PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
           PG  GP G  G  G +G  G  G  GP+G  G+ G  GL G  G  G   F
Sbjct: 607 PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF 657



 Score =  135 bits (340), Expect = 1e-31
 Identities = 89/223 (39%), Positives = 101/223 (45%), Gaps = 61/223 (27%)

Query: 440 AVDTQHGEILRNVTI-LRGAPGP------------PGPRGFKGDMGVKGPVGGRGPK--- 483
           A + Q   IL+   + LRG PGP            PG  G KG+ G  GP G RGP+   
Sbjct: 383 AQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLT 442

Query: 484 ---------------------GDP------------------GSLGPLGPQGPQGQPGEA 504
                                GDP                  G  G  G QG  G PGE 
Sbjct: 443 GPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED 502

Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS---GPQ 561
           G  G+ G +GPRG PG  G +G  G  GP G PGP G  G  GP+GP GS GP    GP 
Sbjct: 503 GERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP 562

Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP---GPPG 601
           G+ G  G  G PG +GA+GP GE G QG PGLPG P   GPPG
Sbjct: 563 GQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPG 605



 Score =  135 bits (340), Expect = 1e-31
 Identities = 74/167 (44%), Positives = 87/167 (52%), Gaps = 21/167 (12%)

Query: 456 RGAPGPPGPRGFKGDMGVKG------------------PVGGRGPKGDPGSLGPLGPQGP 497
           +G  G  G  GFKGD+GVKG                  P G  GP GDPG  G +G +G 
Sbjct: 649 KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 708

Query: 498 QGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEG---PPGS 554
            G PG  G  G +GP G  GFPG  G+ G  G  G  G+ GP+G+ GP GP G   P G+
Sbjct: 709 LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 768

Query: 555 PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G SG +G  G  G  G PG+RG  GP+G  G  GP G PGPPG  G
Sbjct: 769 TGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDG 815



 Score =  133 bits (335), Expect = 4e-31
 Identities = 72/162 (44%), Positives = 82/162 (50%), Gaps = 15/162 (9%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG----- 511
            G  GPPGP G  G+ G  G  G  GP G PG  GP G  G +G PGE GP+G  G     
Sbjct: 920  GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 979

Query: 512  -------PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEG---PPGSPGPSGPQ 561
                   P GP G  G  G KG  G  G +G  G KG+ GPPGP G   P G PG +G  
Sbjct: 980  GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGAD 1039

Query: 562  GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G+PG  G  G  G +G  G +G  G  GP GL G PGP G +
Sbjct: 1040 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEK 1081



 Score =  132 bits (333), Expect = 7e-31
 Identities = 76/161 (47%), Positives = 87/161 (54%), Gaps = 18/161 (11%)

Query: 455  LRGAPGPPGPRGFKGDMGVKG------PVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG 508
            ++G PG  GPRG +G+ G  G      P G +GP GD    GP G  GP G PG+ GP G
Sbjct: 1137 IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD---GPKGNPGPVGFPGDPGPPG 1193

Query: 509  ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP---EGPPGSPGPSGPQGKPG 565
            E    GPRG  G KG +G  G  G  G PGP G+ GPPGP    GP GSPG  G QG  G
Sbjct: 1194 EG---GPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKG 1250

Query: 566  I---AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
                 G  G+PG+ G +GP G  G  GP GL G PG  G Q
Sbjct: 1251 AKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQ 1291



 Score =  129 bits (323), Expect = 1e-29
 Identities = 76/157 (48%), Positives = 82/157 (52%), Gaps = 9/157 (5%)

Query: 456 RGAPGPPGPRGF---KGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
           RG PG  GPRG    KG  G+ GP G RG  G  G  G LGPQG  G PG+ G  G +G 
Sbjct: 514 RGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGL 573

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP---GSPGPSGPQGK---PGI 566
            GP+G  G  G KG  G  G  G PG  G  G PG EGPP   G+ GPSGPQG    PG 
Sbjct: 574 PGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGP 633

Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G  G  G RG  G KGE G  G PG  G  G  G +
Sbjct: 634 RGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDR 670



 Score =  127 bits (318), Expect = 4e-29
 Identities = 76/185 (41%), Positives = 89/185 (48%), Gaps = 39/185 (21%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPVGERGP 512
           +G  G PGPRG KG  G++G  G +G KG+   PG  G +G +G +G+ G  G  GE GP
Sbjct: 625 QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGP 684

Query: 513 VGPRGF---------PGLKGSKGSFGTGGPRGQPG---PKGDIGPP-------------- 546
            GP+G          PGL G KG  G  G  G PG   PKG +G P              
Sbjct: 685 EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 744

Query: 547 ----------GPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGP 596
                     GP GP G  GP G  GK G  G +G  G  G  G +G PG QGP G PGP
Sbjct: 745 SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 804

Query: 597 PGPPG 601
            GPPG
Sbjct: 805 KGPPG 809



 Score =  124 bits (310), Expect = 3e-28
 Identities = 68/150 (45%), Positives = 76/150 (50%), Gaps = 3/150 (2%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
           L G PG  GP G  G  G  G  G +GP G  G LG  GP+G +G  G  G  G +G  G
Sbjct: 594 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 653

Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPE---GPPGSPGPSGPQGKPGIAGKTG 571
             GFPG KG  G  G  G  G PG +G+ GP GP+   GP G PGP G  G+ G  G  G
Sbjct: 654 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 713

Query: 572 SPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            PG  G  GPKG  G  G PG  G  G  G
Sbjct: 714 LPGYPGRQGPKGSLGFPGFPGASGEKGARG 743



 Score =  120 bits (300), Expect = 5e-27
 Identities = 69/163 (42%), Positives = 88/163 (53%), Gaps = 18/163 (11%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG-- 514
           G  GPPG +G +G  G +GP+G  GP+G  G  G  G +G +G+ GE G  G +G +G  
Sbjct: 608 GKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVK 667

Query: 515 -PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------PGSPGPSGPQGK- 563
             RG  G+ GS+G  G  GP+G+ GP GD GPPG  G          PG PG  GP+G  
Sbjct: 668 GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL 727

Query: 564 -----PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
                PG +G+ G+ G  G  GP+GE G  GP G  GP G  G
Sbjct: 728 GFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATG 770



 Score =  114 bits (285), Expect = 3e-25
 Identities = 73/200 (36%), Positives = 84/200 (42%), Gaps = 49/200 (24%)

Query: 448 ILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV 507
           +L    ++ G PGP GP G  G  G++   G  GP GDPG  GP G  G  G  G  GP 
Sbjct: 304 VLEPGMLVEGPPGPEGPAGLIGPPGIQ---GNPGPVGDPGERGPPGRAGLPGSDGAPGPP 360

Query: 508 --------------GERGPV--------------------GPRGFPGLKGSKGSFGTGGP 533
                         G++GPV                    GP G  G  G  G  G  G 
Sbjct: 361 GTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGS 420

Query: 534 RGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGL 593
            G  G  GD+GP GP GP G  GP G  G+ G AG  G+ G  G  G KG+ G  G PGL
Sbjct: 421 PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGL 480

Query: 594 PGP------------PGPPG 601
           PG             PGPPG
Sbjct: 481 PGEKGHRGDTGAQGLPGPPG 500



 Score =  111 bits (277), Expect = 2e-24
 Identities = 74/189 (39%), Positives = 84/189 (44%), Gaps = 44/189 (23%)

Query: 458 APGPPGPRGFKGDMGVKGP-VGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           A GP G +G KG+  V  P +   GP G  G  G +GP G QG PG  G  GERGP G  
Sbjct: 289 AHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA 348

Query: 517 GFPGLKGSKGS----------FGTGGP------------------------RGQPGPKGD 542
           G PG  G+ G           FG+GG                         RG PGP G 
Sbjct: 349 GLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGY 408

Query: 543 IGPPGPEGPPGSPGPSG------PQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGP 596
            G PGP G PGSPG  G      PQG  G  G TG PG+ G    +G  G  G  G+PG 
Sbjct: 409 TGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGR---RGRAGADGARGMPGD 465

Query: 597 PGPPGSQSF 605
           PG  G + F
Sbjct: 466 PGVKGDRGF 474



 Score = 92.8 bits (229), Expect = 8e-19
 Identities = 48/97 (49%), Positives = 56/97 (57%), Gaps = 9/97 (9%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPVGERG 511
            L G  GPPG +G KGD G+ GP G  G KG+   PG+ GP+GP GP G PG AGP G +G
Sbjct: 1329 LIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKG 1388

Query: 512  PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548
              GP       G KG  G  GP G PGP G++  P P
Sbjct: 1389 ATGP------GGPKGEKGVQGPPGHPGPPGEVIQPLP 1419



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 49/126 (38%), Positives = 56/126 (44%), Gaps = 17/126 (13%)

Query: 480 RGPKGDPGSLGPLGPQGPQGQ---PGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQ 536
           R P+  P  L     Q PQ Q   PGE   + E   + P                GPRG 
Sbjct: 246 RSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPL----------EEAAHGPRGL 295

Query: 537 PGPKGD--IGPPGP--EGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPG 592
            G KG+  +  PG   EGPPG  GP+G  G PGI G  G  G  G  GP G  G+ G  G
Sbjct: 296 KGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDG 355

Query: 593 LPGPPG 598
            PGPPG
Sbjct: 356 APGPPG 361


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein
           [Homo sapiens]
          Length = 1629

 Score =  156 bits (395), Expect = 5e-38
 Identities = 79/146 (54%), Positives = 89/146 (60%), Gaps = 9/146 (6%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           RG PGPPGP    G+ G+ G  G  G KGDPG  G  G  GP G  G  G   ERG  G 
Sbjct: 835 RGHPGPPGP---PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG---ERGLPGT 888

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
            G PGLKG++G  G  GP G PG +G  G  GP GPPG PGP GP   PG AG+ G PG+
Sbjct: 889 AGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP---PGAAGEKGVPGE 945

Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPG 601
           +G +GP G  G+QGP GLPGP GPPG
Sbjct: 946 KGPIGPTGRDGVQGPVGLPGPAGPPG 971



 Score =  150 bits (380), Expect = 2e-36
 Identities = 84/187 (44%), Positives = 96/187 (51%), Gaps = 45/187 (24%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLG------PLGPQGP------------- 497
            G PGP G RG  G  G +G  GG+G KGDPG++G      P+GP GP             
Sbjct: 1205 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLP 1264

Query: 498  -----QGQPGEAGPVGERGPVGPRGFPGLKGSKGS---------FGTGGPRGQPGPKGDI 543
                 QG+PG  G  G  GPVGP G PGL+G  G+          G  GP G+ G KGD 
Sbjct: 1265 GSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDR 1324

Query: 544  GPPGPEGPPGSP------------GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPP 591
            G PGP+G PG              GP GP G PG AG  G+ G  G  GPKGE G+QGPP
Sbjct: 1325 GLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPP 1384

Query: 592  GLPGPPG 598
            G PGPPG
Sbjct: 1385 GHPGPPG 1391



 Score =  149 bits (376), Expect = 7e-36
 Identities = 85/174 (48%), Positives = 99/174 (56%), Gaps = 27/174 (15%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVG--GR-GPKGD---PGSLGPLGPQGPQGQPGEAGPVGER 510
           G PGPPG  G KG +GV G  G  GR GPKG    PG  G  G +G +G  G++GP GER
Sbjct: 674 GDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER 733

Query: 511 GPVGPRGFPGLKGS---KGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA 567
           GP GPRG  G +G+    G+ GT G  G  GP G+ G PGP+GP G PGP GP G PG  
Sbjct: 734 GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKD 793

Query: 568 GKTGSPGQRGAMGPKGEPGIQGPPGL------------------PGPPGPPGSQ 603
           G  G PGQRG +G +G+ G  GPPG+                  PGPPGPPG Q
Sbjct: 794 GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ 847



 Score =  149 bits (375), Expect = 9e-36
 Identities = 82/171 (47%), Positives = 95/171 (55%), Gaps = 24/171 (14%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGG------RGPKGDPGSLGPLGPQGPQGQPGEAGPVGER 510
            G PGP GP G  G+ G KG VG       +G KG+ G  GP GP GP GQPG AG  GE 
Sbjct: 962  GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEP 1021

Query: 511  GPVGPRGFPGLKGSKGSFGTGGP------RGQPGPKG------DIGPPGPEGPPGSPGPS 558
            G  GP+G  G KG +G+ G  GP      +G PGP G      D+GP GP GPPG  GP+
Sbjct: 1022 GARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPA 1081

Query: 559  ------GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
                  GPQG PG  G  G PG++G  G  G PGIQG PG+ GP G  G +
Sbjct: 1082 GPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEK 1132



 Score =  148 bits (373), Expect = 2e-35
 Identities = 72/148 (48%), Positives = 84/148 (56%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            L+G PGP G +G  GD+G  GP G  GP+G  G  G  GPQGP G  G  GP GE+G  G
Sbjct: 1050 LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1109

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574
              G PG++G  G  G  G RG+ G  G  G PGP GP G  G  GP+G PG  G  G PG
Sbjct: 1110 ESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPG 1169

Query: 575  QRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
              G  GP+G+ G +G  G  G PG PGS
Sbjct: 1170 PPGEGGPRGQDGAKGDRGEDGEPGQPGS 1197



 Score =  147 bits (372), Expect = 2e-35
 Identities = 79/152 (51%), Positives = 89/152 (58%), Gaps = 12/152 (7%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            +G PG  G  G +G+ GVKGP G RG KG+ G  G  GP GP+G  G+ GP G  GPV  
Sbjct: 1105 KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPV-- 1162

Query: 516  RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS------GPQGKPGIAGK 569
             GFP   G  G  G GGPRGQ G KGD G  G  G PGSPGP+      GP GK G AG 
Sbjct: 1163 -GFP---GDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1218

Query: 570  TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
             GS G++G  G KG+PG  G PG  GP GP G
Sbjct: 1219 PGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAG 1250



 Score =  145 bits (367), Expect = 8e-35
 Identities = 75/153 (49%), Positives = 90/153 (58%), Gaps = 9/153 (5%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PG PG +G +GD G +G  G   P G+ G  G  G  GP+G PGE+GP G  GP GP 
Sbjct: 455 GLPGLPGEKGHRGDTGAQGLPG---PPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPP 511

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS---PGPS---GPQGKPGIAGKT 570
           G PG  G +G  G  GP+G  GP+G+ GPPG +G PG+   PGP    GP G+ G  GK 
Sbjct: 512 GIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKP 571

Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           G PG  G+ GP G PG +GPPG  G  GP G Q
Sbjct: 572 GLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQ 604



 Score =  145 bits (367), Expect = 8e-35
 Identities = 76/150 (50%), Positives = 86/150 (57%), Gaps = 9/150 (6%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG---ERGPV 513
            G PGPPGPRG        GP G  GP+G PG +G LGP G +G+PGE+G  G   E G  
Sbjct: 1070 GPPGPPGPRG------PAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVK 1123

Query: 514  GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
            GPRG  G KG  G  G  GP G  GP GD GP G  GP G PG  GP G+ G  G+ G+ 
Sbjct: 1124 GPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAK 1183

Query: 574  GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G RG  G  G+PG  GP G  GPPGP G +
Sbjct: 1184 GDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1213



 Score =  145 bits (366), Expect = 1e-34
 Identities = 81/160 (50%), Positives = 88/160 (55%), Gaps = 12/160 (7%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP--- 512
           RG  G  G RG  GD GVKG  G  G  G PG  G  G  G QG PG  G  GERG    
Sbjct: 430 RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGE 489

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSG---PQGKPGIAGK 569
           +GPRG PG  G +G  G  GP G PGP G  G  GP+GP GS GP G   P G+ G  G 
Sbjct: 490 IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT 549

Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPG------PPGPPGSQ 603
            G PG +GA+GP GE G QG PGLPG      PPG PG +
Sbjct: 550 QGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKE 589



 Score =  145 bits (366), Expect = 1e-34
 Identities = 76/152 (50%), Positives = 89/152 (58%), Gaps = 9/152 (5%)

Query: 457  GAPGPPGP---RGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPV 513
            GAPG  GP   RGF G+ G+ G  GG G KG+ G   P GP GP G PGE G  G  GP+
Sbjct: 866  GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEG---PSGPPGPAGSPGERGAAGSGGPI 922

Query: 514  GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQG---KPGIAGKT 570
            GP G PG +G  G+ G  G  G+ GP G  G  G +GP G PGP+GP G   + G  G+ 
Sbjct: 923  GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 982

Query: 571  GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
            G PGQ+G  G KGE G  GPPG  GP G PG+
Sbjct: 983  GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1014



 Score =  144 bits (363), Expect = 2e-34
 Identities = 76/160 (47%), Positives = 89/160 (55%), Gaps = 18/160 (11%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            GA G PG RG +G  G KG  G RG  G PG +G  G  GP G+ GE G VG  GP GP 
Sbjct: 1016 GADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP- 1074

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI---------A 567
              PG +G  G  G  GP+G PG  G++GPPG +G PG  G  G QG+PG+          
Sbjct: 1075 --PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEK 1132

Query: 568  GKTGSPGQRGAMGPKGEPGIQGPPGLPGP------PGPPG 601
            G++G PG+ G  GPKG  G  GP G PGP      PGPPG
Sbjct: 1133 GESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG 1172



 Score =  142 bits (359), Expect = 7e-34
 Identities = 77/167 (46%), Positives = 91/167 (54%), Gaps = 18/167 (10%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGPVG 508
            L G  G PG +G +G  G  GP G  G +G  GS GP+GP      QGP G  GE G  G
Sbjct: 885  LPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPG 944

Query: 509  ERGPVGPRGFPGLKGSKGSFGTGGP---RGQPGPKGDIGPPGPE---------GPPGSPG 556
            E+GP+GP G  G++G  G  G  GP    G+ G KG++G PG +         GPPG PG
Sbjct: 945  EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG 1004

Query: 557  PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            P GP G+PG AG  G PG RG  G  G  G +G  G  GPPGP G Q
Sbjct: 1005 PIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ 1051



 Score =  142 bits (359), Expect = 7e-34
 Identities = 74/150 (49%), Positives = 88/150 (58%), Gaps = 6/150 (4%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G PG PG  G  G+ G  GP+G RGP G PGS G  G +G +G PG  G  G+ GPVGP 
Sbjct: 1190 GEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPA 1249

Query: 517  G---FPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
            G    PG  G +G  G+ G +G+PG  G  GPPGP GPPG PG    +G  G  G+ G P
Sbjct: 1250 GPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGL---RGDAGAKGEKGHP 1306

Query: 574  GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G  G +GP GE G +G  GLPGP G PG +
Sbjct: 1307 GLIGLIGPPGEQGEKGDRGLPGPQGSPGQK 1336



 Score =  141 bits (356), Expect = 2e-33
 Identities = 77/152 (50%), Positives = 86/152 (56%), Gaps = 9/152 (5%)

Query: 460 GPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQ---GQPGEAGPVGERGPVGPR 516
           GPPGP G+ G  G  G  G  G KG+ G LGP GP+GPQ   G PG+AG  G  G  G R
Sbjct: 380 GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGAR 439

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ- 575
           G PG  G KG  G  G  G PG KG  G  G +G PG PG  G +G  G  G  G PG+ 
Sbjct: 440 GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 499

Query: 576 --RGAMGPKGEPGIQGPP---GLPGPPGPPGS 602
             RG +GPKG PGI GPP   G+ GP GP GS
Sbjct: 500 GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGS 531



 Score =  140 bits (353), Expect = 3e-33
 Identities = 81/167 (48%), Positives = 87/167 (52%), Gaps = 21/167 (12%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGP--- 506
            RGA G  GP G  G  G +GP G  G KG PG  GP+GP      QGP G PG AGP   
Sbjct: 913  RGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGV 972

Query: 507  VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566
             GE G  G  G PG KG+KG+ G  GP G PGP G +G PG  G  G PG  GPQG  G 
Sbjct: 973  AGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGA 1032

Query: 567  AGKTGSPGQRGAMGP------------KGEPGIQGPPGLPGPPGPPG 601
             G  G+ G  G  GP            KGE G  GP G PGPPGP G
Sbjct: 1033 KGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG 1079



 Score =  140 bits (353), Expect = 3e-33
 Identities = 78/165 (47%), Positives = 86/165 (52%), Gaps = 21/165 (12%)

Query: 457  GAPGPPGPRGFKGDMGVKG------------PVGGRGPKGDPGSLGPLGPQGPQGQPGEA 504
            G PGPPGP+G  GD G KG            P G  GP+G  G+ G  G  G  GQPG  
Sbjct: 1139 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSP 1198

Query: 505  GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG------PEGPPGSPGPS 558
            GP GE GP GP G  G  GS GS G  G +G  G  G IG PG      P GP G PGP 
Sbjct: 1199 GPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPD 1258

Query: 559  GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G +G PG  G+ G PG  G  GP   PG  GPPGLPG  G  G++
Sbjct: 1259 GLRGLPGSVGQQGRPGATGQAGP---PGPVGPPGLPGLRGDAGAK 1300



 Score =  140 bits (352), Expect = 4e-33
 Identities = 76/174 (43%), Positives = 86/174 (49%), Gaps = 27/174 (15%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PGPPG RG  G  G KG +G +G  G PG  G  G QG  G  G  GP GE+GP G  
Sbjct: 512 GIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKP 571

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI---------- 566
           G PG+ GS G  G  G  G PG KG+ GP GP+GP G PGP G +G  GI          
Sbjct: 572 GLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEK 631

Query: 567 -----------------AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
                             G+ G PG RG  GP+G  G  GP G PGPPG  G +
Sbjct: 632 GEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEK 685



 Score =  140 bits (352), Expect = 4e-33
 Identities = 79/173 (45%), Positives = 84/173 (48%), Gaps = 27/173 (15%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G  G  GPRG  G  G KG  GG GP G PG  G  GPQGP G PG  GP G  G  G  
Sbjct: 737 GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLP 796

Query: 517 GFPGLKGSKGSFGTGGPRGQP------------GPKGDIGPPGPEGPP------------ 552
           G PG +G  G  G  GP G P            GP G+ G PGP GPP            
Sbjct: 797 GHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKE 856

Query: 553 ---GSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
              G PGP G  GK G AG  G PG+RG  G  G PG++G  G  GPPGP GS
Sbjct: 857 GTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGS 909



 Score =  138 bits (348), Expect = 1e-32
 Identities = 78/174 (44%), Positives = 91/174 (52%), Gaps = 24/174 (13%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGG------RGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509
           +G PGPPG +G  G  G+ GP G       +GP+G PG  G  G  GP G PG+ GP G 
Sbjct: 535 QGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGT 594

Query: 510 RG------PVGPRGFP---------GLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP--- 551
           +G      P GP G+P         G++G KG  G  G  G PG KGDIG  G  G    
Sbjct: 595 KGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV 654

Query: 552 PGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
           PGS G  GP+G  G  G TG PG  G MG KG+ G+ G PG PG  GP GS  F
Sbjct: 655 PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGF 708



 Score =  137 bits (346), Expect = 2e-32
 Identities = 79/166 (47%), Positives = 88/166 (53%), Gaps = 18/166 (10%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG---------EAGP 506
            +G PG  GP G  G  GV+GPVG  GP G PG  G  G +G  G PG         E GP
Sbjct: 940  KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 999

Query: 507  VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD------IGPPGPEGPPGSPGPSGP 560
             G  GP+GP G PG  G+ G  G  GP+G  G KGD       GPPGP G  G PGPSG 
Sbjct: 1000 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1059

Query: 561  QGKPGIA---GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            +G+ G     G  G PG RG  GP G  G QGPPG  G  GPPG +
Sbjct: 1060 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEK 1105



 Score =  137 bits (345), Expect = 3e-32
 Identities = 76/155 (49%), Positives = 84/155 (54%), Gaps = 15/155 (9%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           RG  G  GPRG +G  G +G  G RG  G  G+ G  G  GP G PGE G  G   P GP
Sbjct: 721 RGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPG---PQGP 777

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
            GFPG KG  G  G  G  G PG +G++G  G  GPPG PG  GPQ   G AG+TG  G+
Sbjct: 778 NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ---GAAGETGPMGE 834

Query: 576 RGAMGPKGEPGIQGPPGL---------PGPPGPPG 601
           RG  GP G PG QG PG          PGPPG PG
Sbjct: 835 RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG 869



 Score =  136 bits (342), Expect = 6e-32
 Identities = 74/171 (43%), Positives = 87/171 (50%), Gaps = 15/171 (8%)

Query: 450 RNVTILRGAPGPPG------------PRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGP 497
           R  T  +G PGPPG            PRG  G+ G +G +G +GP G PG  G  G  GP
Sbjct: 466 RGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGP 525

Query: 498 QGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD---IGPPGPEGPPGS 554
           QG  G  GP GE GP G +G PG +G  G  G  GP G+ GP+G     G PG +GPPG 
Sbjct: 526 QGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 585

Query: 555 PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
           PG  GP G  G  G +G  G  G  GP+G  G+ G  GL G  G  G   F
Sbjct: 586 PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF 636



 Score =  135 bits (340), Expect = 1e-31
 Identities = 89/223 (39%), Positives = 101/223 (45%), Gaps = 61/223 (27%)

Query: 440 AVDTQHGEILRNVTI-LRGAPGP------------PGPRGFKGDMGVKGPVGGRGPK--- 483
           A + Q   IL+   + LRG PGP            PG  G KG+ G  GP G RGP+   
Sbjct: 362 AQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLT 421

Query: 484 ---------------------GDP------------------GSLGPLGPQGPQGQPGEA 504
                                GDP                  G  G  G QG  G PGE 
Sbjct: 422 GPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED 481

Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS---GPQ 561
           G  G+ G +GPRG PG  G +G  G  GP G PGP G  G  GP+GP GS GP    GP 
Sbjct: 482 GERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP 541

Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP---GPPG 601
           G+ G  G  G PG +GA+GP GE G QG PGLPG P   GPPG
Sbjct: 542 GQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPG 584



 Score =  135 bits (340), Expect = 1e-31
 Identities = 74/167 (44%), Positives = 87/167 (52%), Gaps = 21/167 (12%)

Query: 456 RGAPGPPGPRGFKGDMGVKG------------------PVGGRGPKGDPGSLGPLGPQGP 497
           +G  G  G  GFKGD+GVKG                  P G  GP GDPG  G +G +G 
Sbjct: 628 KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 687

Query: 498 QGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEG---PPGS 554
            G PG  G  G +GP G  GFPG  G+ G  G  G  G+ GP+G+ GP GP G   P G+
Sbjct: 688 LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 747

Query: 555 PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G SG +G  G  G  G PG+RG  GP+G  G  GP G PGPPG  G
Sbjct: 748 TGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDG 794



 Score =  133 bits (335), Expect = 4e-31
 Identities = 72/162 (44%), Positives = 82/162 (50%), Gaps = 15/162 (9%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG----- 511
            G  GPPGP G  G+ G  G  G  GP G PG  GP G  G +G PGE GP+G  G     
Sbjct: 899  GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 958

Query: 512  -------PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEG---PPGSPGPSGPQ 561
                   P GP G  G  G KG  G  G +G  G KG+ GPPGP G   P G PG +G  
Sbjct: 959  GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGAD 1018

Query: 562  GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G+PG  G  G  G +G  G +G  G  GP GL G PGP G +
Sbjct: 1019 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEK 1060



 Score =  132 bits (333), Expect = 7e-31
 Identities = 76/161 (47%), Positives = 87/161 (54%), Gaps = 18/161 (11%)

Query: 455  LRGAPGPPGPRGFKGDMGVKG------PVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG 508
            ++G PG  GPRG +G+ G  G      P G +GP GD    GP G  GP G PG+ GP G
Sbjct: 1116 IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD---GPKGNPGPVGFPGDPGPPG 1172

Query: 509  ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP---EGPPGSPGPSGPQGKPG 565
            E    GPRG  G KG +G  G  G  G PGP G+ GPPGP    GP GSPG  G QG  G
Sbjct: 1173 EG---GPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKG 1229

Query: 566  I---AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
                 G  G+PG+ G +GP G  G  GP GL G PG  G Q
Sbjct: 1230 AKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQ 1270



 Score =  129 bits (323), Expect = 1e-29
 Identities = 76/157 (48%), Positives = 82/157 (52%), Gaps = 9/157 (5%)

Query: 456 RGAPGPPGPRGF---KGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
           RG PG  GPRG    KG  G+ GP G RG  G  G  G LGPQG  G PG+ G  G +G 
Sbjct: 493 RGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGL 552

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP---GSPGPSGPQGK---PGI 566
            GP+G  G  G KG  G  G  G PG  G  G PG EGPP   G+ GPSGPQG    PG 
Sbjct: 553 PGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGP 612

Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G  G  G RG  G KGE G  G PG  G  G  G +
Sbjct: 613 RGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDR 649



 Score =  127 bits (318), Expect = 4e-29
 Identities = 76/185 (41%), Positives = 89/185 (48%), Gaps = 39/185 (21%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPVGERGP 512
           +G  G PGPRG KG  G++G  G +G KG+   PG  G +G +G +G+ G  G  GE GP
Sbjct: 604 QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGP 663

Query: 513 VGPRGF---------PGLKGSKGSFGTGGPRGQPG---PKGDIGPP-------------- 546
            GP+G          PGL G KG  G  G  G PG   PKG +G P              
Sbjct: 664 EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 723

Query: 547 ----------GPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGP 596
                     GP GP G  GP G  GK G  G +G  G  G  G +G PG QGP G PGP
Sbjct: 724 SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 783

Query: 597 PGPPG 601
            GPPG
Sbjct: 784 KGPPG 788



 Score =  124 bits (310), Expect = 3e-28
 Identities = 68/150 (45%), Positives = 76/150 (50%), Gaps = 3/150 (2%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
           L G PG  GP G  G  G  G  G +GP G  G LG  GP+G +G  G  G  G +G  G
Sbjct: 573 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 632

Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPE---GPPGSPGPSGPQGKPGIAGKTG 571
             GFPG KG  G  G  G  G PG +G+ GP GP+   GP G PGP G  G+ G  G  G
Sbjct: 633 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 692

Query: 572 SPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            PG  G  GPKG  G  G PG  G  G  G
Sbjct: 693 LPGYPGRQGPKGSLGFPGFPGASGEKGARG 722



 Score =  120 bits (300), Expect = 5e-27
 Identities = 69/163 (42%), Positives = 88/163 (53%), Gaps = 18/163 (11%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG-- 514
           G  GPPG +G +G  G +GP+G  GP+G  G  G  G +G +G+ GE G  G +G +G  
Sbjct: 587 GKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVK 646

Query: 515 -PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------PGSPGPSGPQGK- 563
             RG  G+ GS+G  G  GP+G+ GP GD GPPG  G          PG PG  GP+G  
Sbjct: 647 GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL 706

Query: 564 -----PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
                PG +G+ G+ G  G  GP+GE G  GP G  GP G  G
Sbjct: 707 GFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATG 749



 Score =  114 bits (285), Expect = 3e-25
 Identities = 73/200 (36%), Positives = 84/200 (42%), Gaps = 49/200 (24%)

Query: 448 ILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV 507
           +L    ++ G PGP GP G  G  G++   G  GP GDPG  GP G  G  G  G  GP 
Sbjct: 283 VLEPGMLVEGPPGPEGPAGLIGPPGIQ---GNPGPVGDPGERGPPGRAGLPGSDGAPGPP 339

Query: 508 --------------GERGPV--------------------GPRGFPGLKGSKGSFGTGGP 533
                         G++GPV                    GP G  G  G  G  G  G 
Sbjct: 340 GTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGS 399

Query: 534 RGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGL 593
            G  G  GD+GP GP GP G  GP G  G+ G AG  G+ G  G  G KG+ G  G PGL
Sbjct: 400 PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGL 459

Query: 594 PGP------------PGPPG 601
           PG             PGPPG
Sbjct: 460 PGEKGHRGDTGAQGLPGPPG 479



 Score =  111 bits (278), Expect = 2e-24
 Identities = 74/191 (38%), Positives = 85/191 (44%), Gaps = 44/191 (23%)

Query: 456 RGAPGPPGPRGFKGDMGVKGP-VGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
           + A GP G +G KG+  V  P +   GP G  G  G +GP G QG PG  G  GERGP G
Sbjct: 266 QAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPG 325

Query: 515 PRGFPGLKGSKGS----------FGTGGP------------------------RGQPGPK 540
             G PG  G+ G           FG+GG                         RG PGP 
Sbjct: 326 RAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPM 385

Query: 541 GDIGPPGPEGPPGSPGPSG------PQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP 594
           G  G PGP G PGSPG  G      PQG  G  G TG PG+ G    +G  G  G  G+P
Sbjct: 386 GYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGR---RGRAGADGARGMP 442

Query: 595 GPPGPPGSQSF 605
           G PG  G + F
Sbjct: 443 GDPGVKGDRGF 453



 Score = 92.8 bits (229), Expect = 8e-19
 Identities = 48/97 (49%), Positives = 56/97 (57%), Gaps = 9/97 (9%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPVGERG 511
            L G  GPPG +G KGD G+ GP G  G KG+   PG+ GP+GP GP G PG AGP G +G
Sbjct: 1308 LIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKG 1367

Query: 512  PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548
              GP       G KG  G  GP G PGP G++  P P
Sbjct: 1368 ATGP------GGPKGEKGVQGPPGHPGPPGEVIQPLP 1398



 Score = 30.0 bits (66), Expect = 6.4
 Identities = 19/47 (40%), Positives = 23/47 (48%), Gaps = 16/47 (34%)

Query: 573 PGQRGAMGPKG-----------EPG--IQGPPGLPGPP---GPPGSQ 603
           P  + A GP+G           EPG  ++GPPG  GP    GPPG Q
Sbjct: 263 PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQ 309


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score =  156 bits (395), Expect = 5e-38
 Identities = 79/146 (54%), Positives = 89/146 (60%), Gaps = 9/146 (6%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            RG PGPPGP    G+ G+ G  G  G KGDPG  G  G  GP G  G  G   ERG  G 
Sbjct: 942  RGHPGPPGP---PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG---ERGLPGT 995

Query: 516  RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
             G PGLKG++G  G  GP G PG +G  G  GP GPPG PGP GP   PG AG+ G PG+
Sbjct: 996  AGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP---PGAAGEKGVPGE 1052

Query: 576  RGAMGPKGEPGIQGPPGLPGPPGPPG 601
            +G +GP G  G+QGP GLPGP GPPG
Sbjct: 1053 KGPIGPTGRDGVQGPVGLPGPAGPPG 1078



 Score =  150 bits (380), Expect = 2e-36
 Identities = 84/187 (44%), Positives = 96/187 (51%), Gaps = 45/187 (24%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLG------PLGPQGP------------- 497
            G PGP G RG  G  G +G  GG+G KGDPG++G      P+GP GP             
Sbjct: 1312 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLP 1371

Query: 498  -----QGQPGEAGPVGERGPVGPRGFPGLKGSKGS---------FGTGGPRGQPGPKGDI 543
                 QG+PG  G  G  GPVGP G PGL+G  G+          G  GP G+ G KGD 
Sbjct: 1372 GSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDR 1431

Query: 544  GPPGPEGPPGSP------------GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPP 591
            G PGP+G PG              GP GP G PG AG  G+ G  G  GPKGE G+QGPP
Sbjct: 1432 GLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPP 1491

Query: 592  GLPGPPG 598
            G PGPPG
Sbjct: 1492 GHPGPPG 1498



 Score =  149 bits (376), Expect = 7e-36
 Identities = 85/174 (48%), Positives = 99/174 (56%), Gaps = 27/174 (15%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVG--GR-GPKGD---PGSLGPLGPQGPQGQPGEAGPVGER 510
           G PGPPG  G KG +GV G  G  GR GPKG    PG  G  G +G +G  G++GP GER
Sbjct: 781 GDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER 840

Query: 511 GPVGPRGFPGLKGS---KGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA 567
           GP GPRG  G +G+    G+ GT G  G  GP G+ G PGP+GP G PGP GP G PG  
Sbjct: 841 GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKD 900

Query: 568 GKTGSPGQRGAMGPKGEPGIQGPPGL------------------PGPPGPPGSQ 603
           G  G PGQRG +G +G+ G  GPPG+                  PGPPGPPG Q
Sbjct: 901 GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ 954



 Score =  149 bits (375), Expect = 9e-36
 Identities = 82/171 (47%), Positives = 95/171 (55%), Gaps = 24/171 (14%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGG------RGPKGDPGSLGPLGPQGPQGQPGEAGPVGER 510
            G PGP GP G  G+ G KG VG       +G KG+ G  GP GP GP GQPG AG  GE 
Sbjct: 1069 GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEP 1128

Query: 511  GPVGPRGFPGLKGSKGSFGTGGP------RGQPGPKG------DIGPPGPEGPPGSPGPS 558
            G  GP+G  G KG +G+ G  GP      +G PGP G      D+GP GP GPPG  GP+
Sbjct: 1129 GARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPA 1188

Query: 559  ------GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
                  GPQG PG  G  G PG++G  G  G PGIQG PG+ GP G  G +
Sbjct: 1189 GPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEK 1239



 Score =  148 bits (373), Expect = 2e-35
 Identities = 72/148 (48%), Positives = 84/148 (56%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            L+G PGP G +G  GD+G  GP G  GP+G  G  G  GPQGP G  G  GP GE+G  G
Sbjct: 1157 LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1216

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574
              G PG++G  G  G  G RG+ G  G  G PGP GP G  G  GP+G PG  G  G PG
Sbjct: 1217 ESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPG 1276

Query: 575  QRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
              G  GP+G+ G +G  G  G PG PGS
Sbjct: 1277 PPGEGGPRGQDGAKGDRGEDGEPGQPGS 1304



 Score =  147 bits (372), Expect = 2e-35
 Identities = 79/152 (51%), Positives = 89/152 (58%), Gaps = 12/152 (7%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            +G PG  G  G +G+ GVKGP G RG KG+ G  G  GP GP+G  G+ GP G  GPVG 
Sbjct: 1212 KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG- 1270

Query: 516  RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS------GPQGKPGIAGK 569
              FPG  G  G    GGPRGQ G KGD G  G  G PGSPGP+      GP GK G AG 
Sbjct: 1271 --FPGDPGPPGE---GGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1325

Query: 570  TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
             GS G++G  G KG+PG  G PG  GP GP G
Sbjct: 1326 PGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAG 1357



 Score =  145 bits (367), Expect = 8e-35
 Identities = 75/153 (49%), Positives = 90/153 (58%), Gaps = 9/153 (5%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PG PG +G +GD G +G  G   P G+ G  G  G  GP+G PGE+GP G  GP GP 
Sbjct: 562 GLPGLPGEKGHRGDTGAQGLPG---PPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPP 618

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS---PGPS---GPQGKPGIAGKT 570
           G PG  G +G  G  GP+G  GP+G+ GPPG +G PG+   PGP    GP G+ G  GK 
Sbjct: 619 GIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKP 678

Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           G PG  G+ GP G PG +GPPG  G  GP G Q
Sbjct: 679 GLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQ 711



 Score =  145 bits (367), Expect = 8e-35
 Identities = 76/150 (50%), Positives = 86/150 (57%), Gaps = 9/150 (6%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG---ERGPV 513
            G PGPPGPRG        GP G  GP+G PG +G LGP G +G+PGE+G  G   E G  
Sbjct: 1177 GPPGPPGPRG------PAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVK 1230

Query: 514  GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
            GPRG  G KG  G  G  GP G  GP GD GP G  GP G PG  GP G+ G  G+ G+ 
Sbjct: 1231 GPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAK 1290

Query: 574  GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G RG  G  G+PG  GP G  GPPGP G +
Sbjct: 1291 GDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1320



 Score =  145 bits (366), Expect = 1e-34
 Identities = 81/160 (50%), Positives = 88/160 (55%), Gaps = 12/160 (7%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP--- 512
           RG  G  G RG  GD GVKG  G  G  G PG  G  G  G QG PG  G  GERG    
Sbjct: 537 RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGE 596

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSG---PQGKPGIAGK 569
           +GPRG PG  G +G  G  GP G PGP G  G  GP+GP GS GP G   P G+ G  G 
Sbjct: 597 IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT 656

Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPG------PPGPPGSQ 603
            G PG +GA+GP GE G QG PGLPG      PPG PG +
Sbjct: 657 QGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKE 696



 Score =  145 bits (366), Expect = 1e-34
 Identities = 76/152 (50%), Positives = 89/152 (58%), Gaps = 9/152 (5%)

Query: 457  GAPGPPGP---RGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPV 513
            GAPG  GP   RGF G+ G+ G  GG G KG+ G   P GP GP G PGE G  G  GP+
Sbjct: 973  GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEG---PSGPPGPAGSPGERGAAGSGGPI 1029

Query: 514  GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQG---KPGIAGKT 570
            GP G PG +G  G+ G  G  G+ GP G  G  G +GP G PGP+GP G   + G  G+ 
Sbjct: 1030 GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 1089

Query: 571  GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
            G PGQ+G  G KGE G  GPPG  GP G PG+
Sbjct: 1090 GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1121



 Score =  144 bits (363), Expect = 2e-34
 Identities = 76/160 (47%), Positives = 89/160 (55%), Gaps = 18/160 (11%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            GA G PG RG +G  G KG  G RG  G PG +G  G  GP G+ GE G VG  GP GP 
Sbjct: 1123 GADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP- 1181

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI---------A 567
              PG +G  G  G  GP+G PG  G++GPPG +G PG  G  G QG+PG+          
Sbjct: 1182 --PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEK 1239

Query: 568  GKTGSPGQRGAMGPKGEPGIQGPPGLPGP------PGPPG 601
            G++G PG+ G  GPKG  G  GP G PGP      PGPPG
Sbjct: 1240 GESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG 1279



 Score =  142 bits (359), Expect = 7e-34
 Identities = 77/167 (46%), Positives = 91/167 (54%), Gaps = 18/167 (10%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGPVG 508
            L G  G PG +G +G  G  GP G  G +G  GS GP+GP      QGP G  GE G  G
Sbjct: 992  LPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPG 1051

Query: 509  ERGPVGPRGFPGLKGSKGSFGTGGP---RGQPGPKGDIGPPGPEG---------PPGSPG 556
            E+GP+GP G  G++G  G  G  GP    G+ G KG++G PG +G         PPG PG
Sbjct: 1052 EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG 1111

Query: 557  PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            P GP G+PG AG  G PG RG  G  G  G +G  G  GPPGP G Q
Sbjct: 1112 PIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ 1158



 Score =  142 bits (359), Expect = 7e-34
 Identities = 74/150 (49%), Positives = 88/150 (58%), Gaps = 6/150 (4%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G PG PG  G  G+ G  GP+G RGP G PGS G  G +G +G PG  G  G+ GPVGP 
Sbjct: 1297 GEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPA 1356

Query: 517  G---FPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
            G    PG  G +G  G+ G +G+PG  G  GPPGP GPPG PG    +G  G  G+ G P
Sbjct: 1357 GPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGL---RGDAGAKGEKGHP 1413

Query: 574  GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G  G +GP GE G +G  GLPGP G PG +
Sbjct: 1414 GLIGLIGPPGEQGEKGDRGLPGPQGSPGQK 1443



 Score =  141 bits (356), Expect = 2e-33
 Identities = 77/152 (50%), Positives = 86/152 (56%), Gaps = 9/152 (5%)

Query: 460 GPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQ---GQPGEAGPVGERGPVGPR 516
           GPPGP G+ G  G  G  G  G KG+ G LGP GP+GPQ   G PG+AG  G  G  G R
Sbjct: 487 GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGAR 546

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ- 575
           G PG  G KG  G  G  G PG KG  G  G +G PG PG  G +G  G  G  G PG+ 
Sbjct: 547 GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 606

Query: 576 --RGAMGPKGEPGIQGPP---GLPGPPGPPGS 602
             RG +GPKG PGI GPP   G+ GP GP GS
Sbjct: 607 GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGS 638



 Score =  140 bits (353), Expect = 3e-33
 Identities = 81/167 (48%), Positives = 87/167 (52%), Gaps = 21/167 (12%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGP--- 506
            RGA G  GP G  G  G +GP G  G KG PG  GP+GP      QGP G PG AGP   
Sbjct: 1020 RGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGV 1079

Query: 507  VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566
             GE G  G  G PG KG+KG+ G  GP G PGP G +G PG  G  G PG  GPQG  G 
Sbjct: 1080 AGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGA 1139

Query: 567  AGKTGSPGQRGAMGP------------KGEPGIQGPPGLPGPPGPPG 601
             G  G+ G  G  GP            KGE G  GP G PGPPGP G
Sbjct: 1140 KGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG 1186



 Score =  140 bits (353), Expect = 3e-33
 Identities = 78/165 (47%), Positives = 86/165 (52%), Gaps = 21/165 (12%)

Query: 457  GAPGPPGPRGFKGDMGVKG------------PVGGRGPKGDPGSLGPLGPQGPQGQPGEA 504
            G PGPPGP+G  GD G KG            P G  GP+G  G+ G  G  G  GQPG  
Sbjct: 1246 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSP 1305

Query: 505  GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG------PEGPPGSPGPS 558
            GP GE GP GP G  G  GS GS G  G +G  G  G IG PG      P GP G PGP 
Sbjct: 1306 GPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPD 1365

Query: 559  GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G +G PG  G+ G PG  G  GP   PG  GPPGLPG  G  G++
Sbjct: 1366 GLRGLPGSVGQQGRPGATGQAGP---PGPVGPPGLPGLRGDAGAK 1407



 Score =  140 bits (352), Expect = 4e-33
 Identities = 76/174 (43%), Positives = 86/174 (49%), Gaps = 27/174 (15%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PGPPG RG  G  G KG +G +G  G PG  G  G QG  G  G  GP GE+GP G  
Sbjct: 619 GIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKP 678

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI---------- 566
           G PG+ GS G  G  G  G PG KG+ GP GP+GP G PGP G +G  GI          
Sbjct: 679 GLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEK 738

Query: 567 -----------------AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
                             G+ G PG RG  GP+G  G  GP G PGPPG  G +
Sbjct: 739 GEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEK 792



 Score =  140 bits (352), Expect = 4e-33
 Identities = 79/173 (45%), Positives = 84/173 (48%), Gaps = 27/173 (15%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G  G  GPRG  G  G KG  GG GP G PG  G  GPQGP G PG  GP G  G  G  
Sbjct: 844  GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLP 903

Query: 517  GFPGLKGSKGSFGTGGPRGQP------------GPKGDIGPPGPEGPP------------ 552
            G PG +G  G  G  GP G P            GP G+ G PGP GPP            
Sbjct: 904  GHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKE 963

Query: 553  ---GSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
               G PGP G  GK G AG  G PG+RG  G  G PG++G  G  GPPGP GS
Sbjct: 964  GTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGS 1016



 Score =  138 bits (348), Expect = 1e-32
 Identities = 78/174 (44%), Positives = 91/174 (52%), Gaps = 24/174 (13%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGG------RGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509
           +G PGPPG +G  G  G+ GP G       +GP+G PG  G  G  GP G PG+ GP G 
Sbjct: 642 QGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGT 701

Query: 510 RG------PVGPRGFP---------GLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP--- 551
           +G      P GP G+P         G++G KG  G  G  G PG KGDIG  G  G    
Sbjct: 702 KGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV 761

Query: 552 PGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
           PGS G  GP+G  G  G TG PG  G MG KG+ G+ G PG PG  GP GS  F
Sbjct: 762 PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGF 815



 Score =  137 bits (346), Expect = 2e-32
 Identities = 79/166 (47%), Positives = 88/166 (53%), Gaps = 18/166 (10%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG---------EAGP 506
            +G PG  GP G  G  GV+GPVG  GP G PG  G  G +G  G PG         E GP
Sbjct: 1047 KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 1106

Query: 507  VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD------IGPPGPEGPPGSPGPSGP 560
             G  GP+GP G PG  G+ G  G  GP+G  G KGD       GPPGP G  G PGPSG 
Sbjct: 1107 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1166

Query: 561  QGKPGIA---GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            +G+ G     G  G PG RG  GP G  G QGPPG  G  GPPG +
Sbjct: 1167 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEK 1212



 Score =  137 bits (345), Expect = 3e-32
 Identities = 76/155 (49%), Positives = 84/155 (54%), Gaps = 15/155 (9%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           RG  G  GPRG +G  G +G  G RG  G  G+ G  G  GP G PGE G  G   P GP
Sbjct: 828 RGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPG---PQGP 884

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
            GFPG KG  G  G  G  G PG +G++G  G  GPPG PG  GPQ   G AG+TG  G+
Sbjct: 885 NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ---GAAGETGPMGE 941

Query: 576 RGAMGPKGEPGIQGPPGL---------PGPPGPPG 601
           RG  GP G PG QG PG          PGPPG PG
Sbjct: 942 RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG 976



 Score =  136 bits (342), Expect = 6e-32
 Identities = 74/171 (43%), Positives = 87/171 (50%), Gaps = 15/171 (8%)

Query: 450 RNVTILRGAPGPPG------------PRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGP 497
           R  T  +G PGPPG            PRG  G+ G +G +G +GP G PG  G  G  GP
Sbjct: 573 RGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGP 632

Query: 498 QGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD---IGPPGPEGPPGS 554
           QG  G  GP GE GP G +G PG +G  G  G  GP G+ GP+G     G PG +GPPG 
Sbjct: 633 QGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 692

Query: 555 PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
           PG  GP G  G  G +G  G  G  GP+G  G+ G  GL G  G  G   F
Sbjct: 693 PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF 743



 Score =  135 bits (340), Expect = 1e-31
 Identities = 89/223 (39%), Positives = 101/223 (45%), Gaps = 61/223 (27%)

Query: 440 AVDTQHGEILRNVTI-LRGAPGP------------PGPRGFKGDMGVKGPVGGRGPK--- 483
           A + Q   IL+   + LRG PGP            PG  G KG+ G  GP G RGP+   
Sbjct: 469 AQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLT 528

Query: 484 ---------------------GDP------------------GSLGPLGPQGPQGQPGEA 504
                                GDP                  G  G  G QG  G PGE 
Sbjct: 529 GPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED 588

Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS---GPQ 561
           G  G+ G +GPRG PG  G +G  G  GP G PGP G  G  GP+GP GS GP    GP 
Sbjct: 589 GERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP 648

Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP---GPPG 601
           G+ G  G  G PG +GA+GP GE G QG PGLPG P   GPPG
Sbjct: 649 GQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPG 691



 Score =  135 bits (340), Expect = 1e-31
 Identities = 74/167 (44%), Positives = 87/167 (52%), Gaps = 21/167 (12%)

Query: 456 RGAPGPPGPRGFKGDMGVKG------------------PVGGRGPKGDPGSLGPLGPQGP 497
           +G  G  G  GFKGD+GVKG                  P G  GP GDPG  G +G +G 
Sbjct: 735 KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 794

Query: 498 QGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEG---PPGS 554
            G PG  G  G +GP G  GFPG  G+ G  G  G  G+ GP+G+ GP GP G   P G+
Sbjct: 795 LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 854

Query: 555 PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G SG +G  G  G  G PG+RG  GP+G  G  GP G PGPPG  G
Sbjct: 855 TGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDG 901



 Score =  133 bits (335), Expect = 4e-31
 Identities = 72/162 (44%), Positives = 82/162 (50%), Gaps = 15/162 (9%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG----- 511
            G  GPPGP G  G+ G  G  G  GP G PG  GP G  G +G PGE GP+G  G     
Sbjct: 1006 GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 1065

Query: 512  -------PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEG---PPGSPGPSGPQ 561
                   P GP G  G  G KG  G  G +G  G KG+ GPPGP G   P G PG +G  
Sbjct: 1066 GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGAD 1125

Query: 562  GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G+PG  G  G  G +G  G +G  G  GP GL G PGP G +
Sbjct: 1126 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEK 1167



 Score =  132 bits (333), Expect = 7e-31
 Identities = 76/161 (47%), Positives = 87/161 (54%), Gaps = 18/161 (11%)

Query: 455  LRGAPGPPGPRGFKGDMGVKG------PVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG 508
            ++G PG  GPRG +G+ G  G      P G +GP GD    GP G  GP G PG+ GP G
Sbjct: 1223 IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD---GPKGNPGPVGFPGDPGPPG 1279

Query: 509  ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP---EGPPGSPGPSGPQGKPG 565
            E    GPRG  G KG +G  G  G  G PGP G+ GPPGP    GP GSPG  G QG  G
Sbjct: 1280 EG---GPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKG 1336

Query: 566  I---AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
                 G  G+PG+ G +GP G  G  GP GL G PG  G Q
Sbjct: 1337 AKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQ 1377



 Score =  129 bits (323), Expect = 1e-29
 Identities = 76/157 (48%), Positives = 82/157 (52%), Gaps = 9/157 (5%)

Query: 456 RGAPGPPGPRGF---KGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
           RG PG  GPRG    KG  G+ GP G RG  G  G  G LGPQG  G PG+ G  G +G 
Sbjct: 600 RGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGL 659

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP---GSPGPSGPQGK---PGI 566
            GP+G  G  G KG  G  G  G PG  G  G PG EGPP   G+ GPSGPQG    PG 
Sbjct: 660 PGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGP 719

Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G  G  G RG  G KGE G  G PG  G  G  G +
Sbjct: 720 RGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDR 756



 Score =  127 bits (318), Expect = 4e-29
 Identities = 76/185 (41%), Positives = 89/185 (48%), Gaps = 39/185 (21%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPVGERGP 512
           +G  G PGPRG KG  G++G  G +G KG+   PG  G +G +G +G+ G  G  GE GP
Sbjct: 711 QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGP 770

Query: 513 VGPRGF---------PGLKGSKGSFGTGGPRGQPG---PKGDIGPP-------------- 546
            GP+G          PGL G KG  G  G  G PG   PKG +G P              
Sbjct: 771 EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 830

Query: 547 ----------GPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGP 596
                     GP GP G  GP G  GK G  G +G  G  G  G +G PG QGP G PGP
Sbjct: 831 SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 890

Query: 597 PGPPG 601
            GPPG
Sbjct: 891 KGPPG 895



 Score =  124 bits (310), Expect = 3e-28
 Identities = 68/150 (45%), Positives = 76/150 (50%), Gaps = 3/150 (2%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
           L G PG  GP G  G  G  G  G +GP G  G LG  GP+G +G  G  G  G +G  G
Sbjct: 680 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 739

Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPE---GPPGSPGPSGPQGKPGIAGKTG 571
             GFPG KG  G  G  G  G PG +G+ GP GP+   GP G PGP G  G+ G  G  G
Sbjct: 740 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 799

Query: 572 SPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            PG  G  GPKG  G  G PG  G  G  G
Sbjct: 800 LPGYPGRQGPKGSLGFPGFPGASGEKGARG 829



 Score =  120 bits (300), Expect = 5e-27
 Identities = 69/163 (42%), Positives = 88/163 (53%), Gaps = 18/163 (11%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG-- 514
           G  GPPG +G +G  G +GP+G  GP+G  G  G  G +G +G+ GE G  G +G +G  
Sbjct: 694 GKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVK 753

Query: 515 -PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------PGSPGPSGPQGK- 563
             RG  G+ GS+G  G  GP+G+ GP GD GPPG  G          PG PG  GP+G  
Sbjct: 754 GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL 813

Query: 564 -----PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
                PG +G+ G+ G  G  GP+GE G  GP G  GP G  G
Sbjct: 814 GFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATG 856



 Score =  112 bits (280), Expect = 1e-24
 Identities = 79/207 (38%), Positives = 91/207 (43%), Gaps = 46/207 (22%)

Query: 442 DTQHGEILRNVTILRGAP--GPPGPRGFKGDMGVKGP-VGGRGPKGDPGSLGPLGPQGPQ 498
           +T+ G  L   T   GA   GP G +G KG+  V  P +   GP G  G  G +GP G Q
Sbjct: 357 ETELGPALSAETAHSGAAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQ 416

Query: 499 GQPGEAGPVGERGPVGPRGFPGLKGSKGS----------FGTGGP--------------- 533
           G PG  G  GERGP G  G PG  G+ G           FG+GG                
Sbjct: 417 GNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQA 476

Query: 534 ---------RGQPGPKGDIGPPGPEGPPGSPGPSG------PQGKPGIAGKTGSPGQRGA 578
                    RG PGP G  G PGP G PGSPG  G      PQG  G  G TG PG+ G 
Sbjct: 477 ILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGR 536

Query: 579 MGPKGEPGIQGPPGLPGPPGPPGSQSF 605
              +G  G  G  G+PG PG  G + F
Sbjct: 537 ---RGRAGADGARGMPGDPGVKGDRGF 560



 Score = 92.8 bits (229), Expect = 8e-19
 Identities = 48/97 (49%), Positives = 56/97 (57%), Gaps = 9/97 (9%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPVGERG 511
            L G  GPPG +G KGD G+ GP G  G KG+   PG+ GP+GP GP G PG AGP G +G
Sbjct: 1415 LIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKG 1474

Query: 512  PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548
              GP       G KG  G  GP G PGP G++  P P
Sbjct: 1475 ATGP------GGPKGEKGVQGPPGHPGPPGEVIQPLP 1505



 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 47/126 (37%), Positives = 53/126 (42%), Gaps = 21/126 (16%)

Query: 494 PQGPQGQPGEAGPVGERGPVGPRGF---------------PGLKGSKGSFGTG--GPRGQ 536
           P   + Q  E G  G   P GP  +               P L       G    GPRG 
Sbjct: 322 PTADRFQAEEYGEGGTDPPEGPYDYTYGYGDDYREETELGPALSAETAHSGAAAHGPRGL 381

Query: 537 PGPKGD--IGPPGP--EGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPG 592
            G KG+  +  PG   EGPPG  GP+G  G PGI G  G  G  G  GP G  G+ G  G
Sbjct: 382 KGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDG 441

Query: 593 LPGPPG 598
            PGPPG
Sbjct: 442 APGPPG 447


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score =  156 bits (394), Expect = 6e-38
 Identities = 79/163 (48%), Positives = 94/163 (57%), Gaps = 15/163 (9%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            +G  GPPGP G +G  G++G  G +G  GDPG  G  G +GP G  G  G  GERGP+GP
Sbjct: 958  KGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGP 1017

Query: 516  RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKT----- 570
             G  GL G  GS G  GP G+ G +G+ GPPGP G  G PGP GP G PG AG +     
Sbjct: 1018 AGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGD 1077

Query: 571  ----------GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
                      GS G +G  GP G+PGI+GP G PGPPG  G+Q
Sbjct: 1078 KGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQ 1120



 Score =  152 bits (384), Expect = 9e-37
 Identities = 84/186 (45%), Positives = 100/186 (53%), Gaps = 39/186 (20%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPVGERGPV 513
           G PG PGPRG KG  G +G  G +G KG+   PG  G +G +G QG+PG  GP GE GP 
Sbjct: 704 GPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPE 763

Query: 514 GPRGFPGLKGSKGSFGTGGPR------------GQPGPKGDIGPPGPEGPPGSPGPSGPQ 561
           GP+G  G  G +G  G+ G +            G+PGPKG IG PGP GP G  G SG  
Sbjct: 764 GPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKT 823

Query: 562 GKPGIAGKTGSPGQRGAM---------GPKGE---------------PGIQGPPGLPGPP 597
           G+PG+ G+ G PG RG           GPKG+               PG+QGPPG PGP 
Sbjct: 824 GQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPK 883

Query: 598 GPPGSQ 603
           GPPG Q
Sbjct: 884 GPPGHQ 889



 Score =  148 bits (373), Expect = 2e-35
 Identities = 83/190 (43%), Positives = 98/190 (51%), Gaps = 42/190 (22%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGD------PGSLGPLGPQGPQGQPGEAGPVGE 509
           RG  GP GP+G  G  G +GP G  G KG       PG  G  GP+G  G PG  GP+GE
Sbjct: 757 RGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGE 816

Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPG------PKGDIGP------------PGPEGP 551
           +G  G  G PGL+G +G  G+ G RGQPG      PKGD+G             PG +GP
Sbjct: 817 KGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGP 876

Query: 552 PGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGL------------------ 593
           PG PGP GP G  G  G+ G PGQRG +G +G+ G  GP G+                  
Sbjct: 877 PGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGP 936

Query: 594 PGPPGPPGSQ 603
           PGPPGPPG Q
Sbjct: 937 PGPPGPPGEQ 946



 Score =  147 bits (372), Expect = 2e-35
 Identities = 80/162 (49%), Positives = 94/162 (58%), Gaps = 15/162 (9%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQG---PQGQPGEAGPVGERGPV 513
            G PGP GP G +G  G  G  G RG  G  G  GP GP G   PQG+ GE GP+GERGP 
Sbjct: 878  GFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPP 937

Query: 514  GP------RGFPGL---KGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS---GPQ 561
            GP      +G PGL   +G+KG  G  GP G+ GP G  G PGP+G PG PGP+   G +
Sbjct: 938  GPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDK 997

Query: 562  GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G PG  G  GSPG+RG +GP G  G+ G  G  GP GP G +
Sbjct: 998  GPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKK 1039



 Score =  147 bits (371), Expect = 3e-35
 Identities = 75/154 (48%), Positives = 88/154 (57%), Gaps = 9/154 (5%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G  G PGP G  G+ G  GP G RGP G  G  G  G +G +G+PG  GP G  GP+G R
Sbjct: 1289 GDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGAR 1348

Query: 517  GFPGLKGSKGSFGTGGPRGQPG---PKGDIGPPGPEGPPGSPG------PSGPQGKPGIA 567
            G PG  G +G  G  GP G+PG     G +GPPGP GP G PG      P G +G  G+ 
Sbjct: 1349 GPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLI 1408

Query: 568  GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  G PG+ G  G +G PG+QGPPG  G PGPPG
Sbjct: 1409 GLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPG 1442



 Score =  147 bits (370), Expect = 4e-35
 Identities = 79/151 (52%), Positives = 88/151 (58%), Gaps = 6/151 (3%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP---LGPQGPQGQPGEAGPVGERGPV 513
            GAPGPPG RG  G MG +G  G +G KG+PG  GP    GP G +G PG  GP G RG  
Sbjct: 1304 GAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIP 1363

Query: 514  GPRGFPGLKGSKGSFGTGGPRGQ---PGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKT 570
            GP G PGL G+ G  G  GP G    PG KGD GP G +G  G  G  GP G+ G  G  
Sbjct: 1364 GPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQ 1423

Query: 571  GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G PG +G  GPKG+PG  GP G  G PGPPG
Sbjct: 1424 GLPGVQGPPGPKGDPGPPGPIGSLGHPGPPG 1454



 Score =  146 bits (369), Expect = 5e-35
 Identities = 78/164 (47%), Positives = 89/164 (54%), Gaps = 15/164 (9%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGG---RGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG 511
            L+G PGPPG +G  GD+G  GP G    RGP+G  GS G  G  G  GQPG  G  GERG
Sbjct: 1149 LQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERG 1208

Query: 512  PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS------------PGPSG 559
              G  G PG  G  G  G  G +G  GP G  GPPG +GPPG             PG  G
Sbjct: 1209 DAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLG 1268

Query: 560  PQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            P G PG++G  GSPG++G  G  G PG  G  G PG PGPPG +
Sbjct: 1269 PPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKR 1312



 Score =  143 bits (361), Expect = 4e-34
 Identities = 75/159 (47%), Positives = 91/159 (57%), Gaps = 9/159 (5%)

Query: 456 RGAPGP------PGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509
           +G PGP      PG +G  G+ G+ G  G  GP G PG  GP G +G QG PG AGP G 
Sbjct: 649 QGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGY 708

Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP---SGPQGKPGI 566
            GP G +G  G +G +G  G  G  G PG KGD+G  G +G PG+PGP    GP+G  G 
Sbjct: 709 PGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQ 768

Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
           AG+ G  G  G+ G KG+ G+ G PG PG PGP GS  F
Sbjct: 769 AGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGF 807



 Score =  143 bits (360), Expect = 5e-34
 Identities = 77/162 (47%), Positives = 89/162 (54%), Gaps = 18/162 (11%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            +G PGP GP G  G MG +GP G  GP+G  G  GP+G  G  G PG+ GP    GP+GP
Sbjct: 1330 KGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGP---PGPLGP 1386

Query: 516  RGFPGLKGSKGS---------FGTGGPRGQPGPKGD------IGPPGPEGPPGSPGPSGP 560
             G PGLKG  G           G  GP G+ G KGD       GPPGP+G PG PGP G 
Sbjct: 1387 SGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGS 1446

Query: 561  QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
             G PG  G  G  GQ+G+ G  G  G +G  G  GPPGPPG+
Sbjct: 1447 LGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGA 1488



 Score =  142 bits (357), Expect = 1e-33
 Identities = 78/150 (52%), Positives = 88/150 (58%), Gaps = 12/150 (8%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG---EAGPVGERGPV 513
            GA GPPG  G +G  G+ GPVG  G  G PG +GP GP GP G PG   + GP GE+G +
Sbjct: 1346 GARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHI 1405

Query: 514  GPRGF---PGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKT 570
            G  G    PG  G KG  G  G +G PGPKGD GPPGP G  G PGP G  G  G  G  
Sbjct: 1406 GLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSK 1465

Query: 571  GSPGQRGAMGPKGEPGIQGPPGLPGPPGPP 600
            GSPG   +MGP+G+ G  GPPG   PPG P
Sbjct: 1466 GSPG---SMGPRGDTGPAGPPG---PPGAP 1489



 Score =  141 bits (356), Expect = 2e-33
 Identities = 75/145 (51%), Positives = 84/145 (57%), Gaps = 9/145 (6%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G+ GP GP G KG  G +GP G  G  G PG LGPLGP      PG AGP GE G  G  
Sbjct: 1028 GSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGP------PGAAGPSGEEGDKGDV 1081

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
            G PG KGSKG  G  GP GQPG +G  G PGP   PG+ G  G +G PG+ G+ G  G R
Sbjct: 1082 GAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGP---PGADGAQGRRGPPGLFGQKGDDGVR 1138

Query: 577  GAMGPKGEPGIQGPPGLPGPPGPPG 601
            G +G  G PG+QG PG PG  G  G
Sbjct: 1139 GFVGVIGPPGLQGLPGPPGEKGEVG 1163



 Score =  141 bits (356), Expect = 2e-33
 Identities = 78/157 (49%), Positives = 85/157 (54%), Gaps = 12/157 (7%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRG---PKGDPGSLGPLGPQGPQGQPGEAGPVGE---R 510
            G PG  G +G +GD G  GP G  G   PKGD G  G  GP G  G PG+ GP GE   +
Sbjct: 1196 GQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAK 1255

Query: 511  GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD---IGPPGPEGPPGSPGPSGPQGKPGIA 567
            G VGP G PG  G  G  G  G  G PG KGD   +G PGP G  G PG  GP GK G +
Sbjct: 1256 GSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPS 1315

Query: 568  GKTGSPGQRGAMGPKGEPGIQGPPGLPGP---PGPPG 601
            G  G  G+ G  G KGEPG  GPPG  GP    GPPG
Sbjct: 1316 GHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPG 1352



 Score =  140 bits (354), Expect = 3e-33
 Identities = 76/157 (48%), Positives = 88/157 (56%), Gaps = 12/157 (7%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PG PG +G +GD G  G  G  G  G+ G+ GP GP G  G+PG  G +G RG  GP 
Sbjct: 554 GLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPT 613

Query: 517 GFPG---LKGSKGSFGTGGPRGQPGPKGDIGP------PGPEGPPGSPGPSGPQGKPGIA 567
           G PG   + G+ G+ G  GP G+PGP G  G       PGP+G  G+PG  GP G PGI 
Sbjct: 614 GRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIP 673

Query: 568 GKTGSP---GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           G  GS    G  G  GP GE G QGPPG  GPPG PG
Sbjct: 674 GLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPG 710



 Score =  140 bits (352), Expect = 4e-33
 Identities = 78/170 (45%), Positives = 93/170 (54%), Gaps = 21/170 (12%)

Query: 455 LRGAPGP---PGPRGFKGDMGVKGPVGGRG---PKGDPGSLGPLG---PQGPQGQPGEAG 505
           L G PGP   PG  G KG+ G +GP G RG   P G PG +G +G     G +G PG+ G
Sbjct: 486 LTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTG 545

Query: 506 PVGERGPVGPRGFPGLKGSKGSFG---TGGPRGQPGPKGDIGPPGPEGPPGSPGPSG--- 559
           P G+RG  G  G PG KG +G FG     GP G+ G +G  GPPGP G  G PGP G   
Sbjct: 546 PKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLG 605

Query: 560 ------PQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
                 P G+PG+ G  G+PG +G +GP GEPG  G  G  G  G PG Q
Sbjct: 606 PRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQ 655



 Score =  139 bits (350), Expect = 8e-33
 Identities = 78/169 (46%), Positives = 85/169 (50%), Gaps = 24/169 (14%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGP---KGDPGSLGPLGPQGPQGQPGEAGPVGERGPV 513
            GAPG PGP+G  G+ G  GP G  GP   KG PG  G  G  GP G PG+ GP G+ G  
Sbjct: 1217 GAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVS 1276

Query: 514  GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPG---------------SPGPS 558
            G  G PG KG  G  G  GP G  G  G  GPPG  GP G                PGP 
Sbjct: 1277 GIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPD 1336

Query: 559  GPQGKPGIAGKTGSPGQ------RGAMGPKGEPGIQGPPGLPGPPGPPG 601
            GP G+ G  G  G PG+      RG  GP GEPG+ G PG  GPPGP G
Sbjct: 1337 GPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLG 1385



 Score =  139 bits (349), Expect = 1e-32
 Identities = 74/167 (44%), Positives = 86/167 (51%), Gaps = 18/167 (10%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
           ++G PGP G  G  G +G+ G  G +G +G  G  GP G QGP G PG  G +G  G  G
Sbjct: 477 MKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADG 536

Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKG---DIGPPGPEGPPGSPGPSGPQGKPGIAGKTG 571
            RG PG  G KG  G  G  G PG KG   D G  G  GPPG  G  G +G PG  G+ G
Sbjct: 537 ARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAG 596

Query: 572 SPGQRGAMGPKGEPGIQGPPGL---------------PGPPGPPGSQ 603
            PG RG +GP+G PG  G PG+               PG PGPPG Q
Sbjct: 597 EPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQ 643



 Score =  139 bits (349), Expect = 1e-32
 Identities = 81/178 (45%), Positives = 91/178 (51%), Gaps = 33/178 (18%)

Query: 457  GAPGPPGPRG---FKGDMGVKGPVGGRGPKGDPGSLGPLG---PQGPQGQPGE------- 503
            G PG PG RG   F+G  G  GP G  GP+G  G +GPLG   P GP G PGE       
Sbjct: 893  GRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLE 952

Query: 504  -----------AGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDI--------- 543
                        GP+G+ GP G RGFPG KG  G  G  G +G  GP G +         
Sbjct: 953  GREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGER 1012

Query: 544  GPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            GP GP G  G PG SG +G  G AGK GS G+RG  GP G+ GI GP G  GPPG  G
Sbjct: 1013 GPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAG 1070



 Score =  138 bits (347), Expect = 2e-32
 Identities = 72/148 (48%), Positives = 83/148 (56%), Gaps = 6/148 (4%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            GAPG  G +G KGD G  G  G RGP G PG   P G  G QG+ G  G  G++G  G R
Sbjct: 1082 GAPGHKGSKGDKGDAGPPGQPGIRGPAGHPG---PPGADGAQGRRGPPGLFGQKGDDGVR 1138

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGP---QGKPGIAGKTGSP 573
            GF G+ G  G  G  GP G+ G  GD+G  GP G PG  GP GP   +G PG+ G  G P
Sbjct: 1139 GFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQP 1198

Query: 574  GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  G  G +G+ G  GPPG PG PGP G
Sbjct: 1199 GAVGEKGERGDAGDPGPPGAPGIPGPKG 1226



 Score =  137 bits (345), Expect = 3e-32
 Identities = 75/157 (47%), Positives = 84/157 (53%), Gaps = 12/157 (7%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGD------PGSLGPLGPQGP------QGQPGEA 504
            GA GP G  G KGD+G  G  G +G KGD      PG  GP G  GP      QG+ G  
Sbjct: 1067 GAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPP 1126

Query: 505  GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564
            G  G++G  G RGF G+ G  G  G  GP G+ G  GD+G  GP G PG  GP GP G  
Sbjct: 1127 GLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSE 1186

Query: 565  GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  G  G  GQ GA+G KGE G  G PG PG PG PG
Sbjct: 1187 GTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPG 1223



 Score =  135 bits (341), Expect = 8e-32
 Identities = 70/146 (47%), Positives = 80/146 (54%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           RG PG  G  G KGD+G  G  G  G KG PG  GP G  GP+G PG  G  G  G  G 
Sbjct: 841 RGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQ 900

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
           RG  G +G  G  G  G  G  G  G++GP G  GPPG PGP G QG PG+ G+ G+ G+
Sbjct: 901 RGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGE 960

Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  GP G+ G  G  G PGP G PG
Sbjct: 961 LGPPGPLGKEGPAGLRGFPGPKGGPG 986



 Score =  135 bits (341), Expect = 8e-32
 Identities = 76/168 (45%), Positives = 90/168 (53%), Gaps = 21/168 (12%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGS------LGPLGPQGPQGQPGEAGPVG 508
            +RG  G PGP G  G  G +GP G  G KGD G       +GP G QG  G PGE G VG
Sbjct: 1104 IRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVG 1163

Query: 509  ERGPVGPRGFPGLKGSKGSFGTGGPRGQP------------GPKGDIGPPGPEGPPGSPG 556
            + G +GP G PG +G +G  G+ G  G P            G +GD G PGP G PG PG
Sbjct: 1164 DVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPG 1223

Query: 557  PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQ---GPPGLPGPPGPPG 601
            P G  G+ G +G +G+ G  G  GP GE G +   GP GLPG  GPPG
Sbjct: 1224 PKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPG 1271



 Score =  135 bits (339), Expect = 1e-31
 Identities = 72/152 (47%), Positives = 82/152 (53%), Gaps = 6/152 (3%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV---GERGP 512
           RG+PGP G  G  G  G  G  G  GP G+PG  G  G  G QG PG  G +   GE+GP
Sbjct: 607 RGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGP 666

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP---SGPQGKPGIAGK 569
            G  G PGL GS G  G  G  G  G KG  GPPG  GPPG PGP    G  G  G+ G+
Sbjct: 667 PGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGE 726

Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  G+ G  G KG+ G++G  G PG PGP G
Sbjct: 727 KGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRG 758



 Score =  134 bits (337), Expect = 2e-31
 Identities = 72/154 (46%), Positives = 81/154 (52%), Gaps = 9/154 (5%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G PG PG  G KGD+G KG  G  G  G PG  GP G  G +G  G  G  G+ GP G  
Sbjct: 1214 GPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDP 1273

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS---- 572
            G  G+ GS G  G  G  G PGP G  G PG  GPPG  GPSG  G+ G  G+ G+    
Sbjct: 1274 GVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEP 1333

Query: 573  -----PGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
                 PG+ G MG +G PG  GP GL G PGP G
Sbjct: 1334 GPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVG 1367



 Score =  133 bits (334), Expect = 5e-31
 Identities = 68/145 (46%), Positives = 79/145 (54%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PGP G  G  G  G+ G  G  G +G PG  GP GP G QG+ G  G  G+RG +G +
Sbjct: 848 GQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQ 907

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           G  G  G  G  G  G  G+ GP G+ GPPGP GPPG  G  G +G+ G  G+ G PG  
Sbjct: 908 GQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPL 967

Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPG 601
           G  GP G  G  GP G PG PGP G
Sbjct: 968 GKEGPAGLRGFPGPKGGPGDPGPTG 992



 Score =  130 bits (328), Expect = 3e-30
 Identities = 72/148 (48%), Positives = 78/148 (52%), Gaps = 3/148 (2%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           GA G PG  G KGD G  G  G  G KG  G  G +G  GP G+ GE G  G  GP G  
Sbjct: 536 GARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQA 595

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEG---PPGSPGPSGPQGKPGIAGKTGSP 573
           G PG +G  G  G+ GP G+PG  G  G PG +G   PPG PGP G QG  G  G  G  
Sbjct: 596 GEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQ 655

Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           G  G  G KG PG  G PGLPG  GP G
Sbjct: 656 GLIGTPGEKGPPGNPGIPGLPGSDGPLG 683



 Score =  130 bits (327), Expect = 3e-30
 Identities = 75/165 (45%), Positives = 84/165 (50%), Gaps = 18/165 (10%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           RG  GP GP G  G MG  G  G RG  GD G  G  G  G  G PGE G  G+ G VG 
Sbjct: 514 RGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQ 573

Query: 516 RGFPGLKGSKGSFGTGGPRGQ---PGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572
            G PG  G +G+ G  GP GQ   PGP+G +GP G  GP G PG +G  G PG  G  G 
Sbjct: 574 PGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGP 633

Query: 573 PGQRGAMGPKGE---------------PGIQGPPGLPGPPGPPGS 602
           PG+ G  G +G                PG +GPPG PG PG PGS
Sbjct: 634 PGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGS 678



 Score =  126 bits (316), Expect = 7e-29
 Identities = 73/151 (48%), Positives = 79/151 (52%), Gaps = 15/151 (9%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            GAPG PG +G  G   ++GP G  GPKG PG  G  G  G  GQ GE G  G+ GP GP 
Sbjct: 860  GAPGIPGEKGLPG---LQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPA 916

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQ------GKPGIAGKT 570
            G  G +G  G  G  G RG P      GPPGP G  G PG  G +      G PG  GK 
Sbjct: 917  GVLGPQGKTGEVGPLGERGPP------GPPGPPGEQGLPGLEGREGAKGELGPPGPLGKE 970

Query: 571  GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  G RG  GPKG PG  GP GL G  GPPG
Sbjct: 971  GPAGLRGFPGPKGGPGDPGPTGLKGDKGPPG 1001



 Score =  117 bits (294), Expect = 2e-26
 Identities = 71/149 (47%), Positives = 79/149 (53%), Gaps = 24/149 (16%)

Query: 455  LRGAPGP---PGPRGFKGDMGVKGPVGGR---GPKGDPGSLGPLGPQGPQGQPGEAGPVG 508
            LRG PGP   PG  G  G MG  GP+G     G KGD          GP+G+ G  G +G
Sbjct: 1359 LRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGD---------TGPKGEKGHIGLIG 1409

Query: 509  ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAG 568
              GP      PG  G KG  G  G +G PGPKGD GPPGP G  G PGP G  G  G  G
Sbjct: 1410 LIGP------PGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKG 1463

Query: 569  KTGSPGQRGAMGPKGEPGIQGPPGLPGPP 597
              GSP   G+MGP+G+ G  GPPG PG P
Sbjct: 1464 SKGSP---GSMGPRGDTGPAGPPGPPGAP 1489



 Score =  114 bits (285), Expect = 3e-25
 Identities = 75/194 (38%), Positives = 86/194 (44%), Gaps = 48/194 (24%)

Query: 456 RGAPGP---PGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP-------------QGP-- 497
           +G  GP   PGP GF GD G  GP G  G  G  G  GP G              +GP  
Sbjct: 400 QGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPV 459

Query: 498 ------------------QGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGP 539
                             +G PG  G  G  GPVG  G PGLKG +G+ G  GPRG  GP
Sbjct: 460 SFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGP 519

Query: 540 K------GDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPP-- 591
                  G +G PG +G  G PG +GP+G  G  G  G PG++G  G  G  G  GPP  
Sbjct: 520 HGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGE 579

Query: 592 ----GLPGPPGPPG 601
               G  GPPGP G
Sbjct: 580 DGERGAEGPPGPTG 593



 Score =  110 bits (274), Expect = 5e-24
 Identities = 62/141 (43%), Positives = 75/141 (53%), Gaps = 6/141 (4%)

Query: 455  LRGAPG---PPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG 511
            L GAPG   PPGP G  G  G+KG  G +G KG  G +G +GP G  G+ G+ G  G +G
Sbjct: 1371 LLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQG 1430

Query: 512  PVGPRGFPGLKGSKGSFGTGGPRGQPGP---KGDIGPPGPEGPPGSPGPSGPQGKPGIAG 568
            P GP+G PG  G  GS G  GP G  GP   KG  G PG  GP G  GP+GP G PG   
Sbjct: 1431 PPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAPA 1490

Query: 569  KTGSPGQRGAMGPKGEPGIQG 589
            +     +R    P   P ++G
Sbjct: 1491 ELHGLRRRRRFVPVPLPVVEG 1511



 Score =  104 bits (260), Expect = 2e-22
 Identities = 72/173 (41%), Positives = 77/173 (44%), Gaps = 36/173 (20%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG-- 514
           G PG PGP+G          VG  GP G PG  G  GP GP G PG  G  G RGP G  
Sbjct: 392 GPPGAPGPQGV---------VGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTV 442

Query: 515 ---PRGFPG--LKGSKGSFGTG-----------GPRGQPGPKGDIGPPGPEGPPGSPG-- 556
              P  F G   KG   SF                +G PGP G  G PGP G PG PG  
Sbjct: 443 IMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLK 502

Query: 557 ----PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
                 GPQG  G+ G  G PG+ G MG    PG  G  GLPG  GP G + F
Sbjct: 503 GEEGAEGPQGPRGLQGPHGPPGRVGKMG---RPGADGARGLPGDTGPKGDRGF 552



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 52/161 (32%), Positives = 64/161 (39%), Gaps = 40/161 (24%)

Query: 483 KGDPGSLGP--LGPQGPQGQPGEAGP-VGERGPVG-PRGFPGLKGSKGSFGTGGPRGQPG 538
           +GD  ++GP     + P     +  P  GE+G  G P      +  +G  G  GP+G  G
Sbjct: 345 EGDDSTMGPDFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVG 404

Query: 539 PKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG------------------------ 574
           P G  GPPG  G PG PGP+G  G PGI G  G PG                        
Sbjct: 405 PSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQA 464

Query: 575 ------------QRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
                        +G  GP G  G  GP GLPG PG  G +
Sbjct: 465 QAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEE 505


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  155 bits (392), Expect = 1e-37
 Identities = 78/156 (50%), Positives = 90/156 (57%), Gaps = 12/156 (7%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            L+G PGPPG +G  GD+G  GP G  GP+G  G  G  GPQGP G  G  G VGE+G  G
Sbjct: 1211 LQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG 1270

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS---PGPSGPQGKPGIAGKTG 571
              G PG     G  G GGP+G+ G KG+ GPPG  GPPG+   PG  GP+G PG  G  G
Sbjct: 1271 EAGNPG---PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPG 1327

Query: 572  SPGQRGAMGPKGEPGI------QGPPGLPGPPGPPG 601
             PG  G  GP G+ G+       G PG PGPPGP G
Sbjct: 1328 DPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSG 1363



 Score =  152 bits (383), Expect = 1e-36
 Identities = 78/147 (53%), Positives = 88/147 (59%), Gaps = 9/147 (6%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            RG PGPPGP    G+ G+ G  G  G KGDP   GP G  G  G  G  G  GERG  G 
Sbjct: 996  RGHPGPPGP---PGEQGLPGAAGKEGAKGDP---GPQGISGKDGPAGLRGFPGERGLPGA 1049

Query: 516  RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
            +G PGLKG +G  G  GP G PG +G  G  GP G PG PGP GP   PG AG+ G+PG+
Sbjct: 1050 QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGP---PGPAGEKGAPGE 1106

Query: 576  RGAMGPKGEPGIQGPPGLPGPPGPPGS 602
            +G  GP G  G+QGP GLPGP GP GS
Sbjct: 1107 KGPQGPAGRDGVQGPVGLPGPAGPAGS 1133



 Score =  152 bits (383), Expect = 1e-36
 Identities = 78/156 (50%), Positives = 88/156 (56%), Gaps = 12/156 (7%)

Query: 457  GAPGPPGPRGFKGDMGVKGP---------VGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV 507
            G PGPPGPRG +G  G  GP         VGG G KG+PG  G  GP G  G  G  G  
Sbjct: 1231 GPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGER 1290

Query: 508  GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA 567
            GE+G  GP G  G  G+KG  G  GP+G PGP   +G PG  GPPG PGP+G  G  G  
Sbjct: 1291 GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGP---VGFPGDPGPPGEPGPAGQDGVGGDK 1347

Query: 568  GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G+ G PGQ G  GP GE G  GPPG  GPPG  G++
Sbjct: 1348 GEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1383



 Score =  150 bits (380), Expect = 2e-36
 Identities = 78/148 (52%), Positives = 89/148 (60%), Gaps = 9/148 (6%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           RG  G PG  G KG  G +GP G  GP GD G  G  G  GP+G PGEAGP   RG +GP
Sbjct: 612 RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGP---RGLLGP 668

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
           RG PG  G  G  G  GP   PGPKG++GP G  GPPG  G  GPQG PG  G  G PG+
Sbjct: 669 RGTPGAPGQPGMAGVDGP---PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGE 725

Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           +   GP+G+PG+ G PG  GPPG PG +
Sbjct: 726 K---GPQGKPGLAGLPGADGPPGHPGKE 750



 Score =  150 bits (380), Expect = 2e-36
 Identities = 81/167 (48%), Positives = 93/167 (55%), Gaps = 18/167 (10%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLG------PQGPQGQPGEAGPVG 508
            L GA G PG +G +G  G  GPVG  G +G  G+ GP+G      PQGP G  GE G  G
Sbjct: 1046 LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1105

Query: 509  ERGPVGPRGFPGLKGSKGSFGTGGPRGQP---GPKGDIGPPGPE---------GPPGSPG 556
            E+GP GP G  G++G  G  G  GP G P   G KG+IG PG +         GPPG PG
Sbjct: 1106 EKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG 1165

Query: 557  PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
              GP G PGIAG  G PG RG  G  G+ G +G  G PGPPGP G Q
Sbjct: 1166 LQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ 1212



 Score =  150 bits (379), Expect = 3e-36
 Identities = 78/160 (48%), Positives = 94/160 (58%), Gaps = 12/160 (7%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVG--GR-------GPKGDPGSLGPLGPQGPQGQPGEAGP 506
            +G PGP G  G +G  G  GP+G  GR       GP G+ G+ G  GPQGP G+ G  GP
Sbjct: 1062 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1121

Query: 507  VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP---EGPPGSPGPSGPQGK 563
            VG  GP GP G PG  G KG  G  G +G  G KG+ GPPGP   +GP G+PG +G  G+
Sbjct: 1122 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGE 1181

Query: 564  PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            PG  G+ G  GQ+G  G +G PG  GP GL G PGPPG +
Sbjct: 1182 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1221



 Score =  149 bits (376), Expect = 7e-36
 Identities = 75/145 (51%), Positives = 85/145 (58%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G  GPPG  G +G  G KG  G  G +G PG  GP+GPQGP G+PG  G  G  GPVG +
Sbjct: 1372 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1431

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
            G PG  G  G  G  GP G PG KGD G  G +G PG  G  GP G+ G  G  G PG +
Sbjct: 1432 GLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1491

Query: 577  GAMGPKGEPGIQGPPGLPGPPGPPG 601
            G+ G KG+ GI GP G  GPPGPPG
Sbjct: 1492 GSPGAKGDGGIPGPAGPLGPPGPPG 1516



 Score =  147 bits (371), Expect = 3e-35
 Identities = 79/168 (47%), Positives = 93/168 (55%), Gaps = 4/168 (2%)

Query: 438 MKAVDTQHGEILRNVTI-LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQG 496
           + A + Q   IL+   I LRG PGP G  G  G +G  G  G +G  GDPG  GP G QG
Sbjct: 521 ISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQG 580

Query: 497 PQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPG 556
           P G  G+ G  G  G  G RG PG  G+KG  G  G  G PG KG  G  GP+GPPG PG
Sbjct: 581 PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 640

Query: 557 PSGPQGKPGIAGKTGSPGQ---RGAMGPKGEPGIQGPPGLPGPPGPPG 601
             G +G+ G  G  G PG+   RG +GP+G PG  G PG+ G  GPPG
Sbjct: 641 DDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 688



 Score =  146 bits (369), Expect = 5e-35
 Identities = 73/146 (50%), Positives = 82/146 (56%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            +G PG  G  G  G+ GV GP G RG KG+ G  G  GP G +G PG+ GP G  GPVG 
Sbjct: 1266 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1325

Query: 516  RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
             G PG  G  G  G  G  G  G  GD G PGP GP G  GP GP GK G  G  G+ G+
Sbjct: 1326 PGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGR 1385

Query: 576  RGAMGPKGEPGIQGPPGLPGPPGPPG 601
            +G  G KGE G +GPPG  GP GP G
Sbjct: 1386 QGEKGAKGEAGAEGPPGKTGPVGPQG 1411



 Score =  145 bits (366), Expect = 1e-34
 Identities = 76/170 (44%), Positives = 90/170 (52%), Gaps = 24/170 (14%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG---ERGP 512
           RG PG PG  G  G  G  GP G  GP+G+PG  G  G  GPQG PG  GP+G   E+GP
Sbjct: 669 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 728

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572
            G  G  GL G+ G  G  G  GQ G KG +GPPGP+GP G PGP G +G  G+ G  GS
Sbjct: 729 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 788

Query: 573 PGQR---------------------GAMGPKGEPGIQGPPGLPGPPGPPG 601
            G++                     G +GP+GE G +GP G  GP G PG
Sbjct: 789 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 838



 Score =  144 bits (364), Expect = 2e-34
 Identities = 84/174 (48%), Positives = 94/174 (54%), Gaps = 27/174 (15%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVG--GR-GPKGD---PGSLGPLGPQGPQGQPGEAGPVGER 510
            G PGP G  G KG +GV G  G  GR GPKG    PG  G  G +G +G  G+ GP G+R
Sbjct: 835  GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 894

Query: 511  GPVGPRGFPGLKGSKGS---FGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP--- 564
            GP GPRG  G +G  G     GT G  G PGP G+ GP GP+GP G PGP GP G P   
Sbjct: 895  GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 954

Query: 565  ------------GIAGKTGSPGQRGAMGPKGEPGIQGP---PGLPGPPGPPGSQ 603
                        G  GKTG PG  G +GP+G  G  GP    G PGPPGPPG Q
Sbjct: 955  GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQ 1008



 Score =  144 bits (364), Expect = 2e-34
 Identities = 82/189 (43%), Positives = 93/189 (49%), Gaps = 42/189 (22%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG- 514
            RG  G PGPRG +G  G +G  G RGP G PG  G  G  GP G PGE GP G +GPVG 
Sbjct: 882  RGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGF 941

Query: 515  --PRG---------FPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------PGS 554
              P+G          PG  G +G  G  G  G PGP G +GP GP G          PG 
Sbjct: 942  PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 1001

Query: 555  PGPSGPQGKPGIAGKTGS---------------------PGQRGAMGPKGEPGIQGPPGL 593
            PGP G QG PG AGK G+                     PG+RG  G +G PG++G  G 
Sbjct: 1002 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1061

Query: 594  PGPPGPPGS 602
             GPPGP GS
Sbjct: 1062 QGPPGPVGS 1070



 Score =  144 bits (364), Expect = 2e-34
 Identities = 74/150 (49%), Positives = 86/150 (57%), Gaps = 6/150 (4%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            + G  GP G RGF G+ G+ G  G  G KG  G   P GP GP G PGE G  G  GP+G
Sbjct: 1028 ISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEG---PQGPPGPVGSPGERGSAGTAGPIG 1084

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP---GIAGKTG 571
              G PG +G  G  G  G  G+ GP+G  G  G +GP G PGP+GP G P   G  G+ G
Sbjct: 1085 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG 1144

Query: 572  SPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
             PGQ+G+ G KGE G  GPPGL GP G PG
Sbjct: 1145 EPGQKGSKGDKGENGPPGPPGLQGPVGAPG 1174



 Score =  144 bits (363), Expect = 2e-34
 Identities = 78/159 (49%), Positives = 87/159 (54%), Gaps = 12/159 (7%)

Query: 457  GAPGPPG------PRGFKGDMGVKGPVGGRGP---KGDPGSLGPLGPQGPQGQPGEAGPV 507
            G PGPPG      P+G +G+ G  GP G  GP   KG PG  GP G  GP G PG+ GP 
Sbjct: 1273 GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP 1332

Query: 508  GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI- 566
            GE GP G  G  G KG  G  G  GP G  G  G  GPPG  GPPG+ G  G QG+ G  
Sbjct: 1333 GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAK 1392

Query: 567  --AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
              AG  G PG+ G +GP+G  G  GP GL G PGP G Q
Sbjct: 1393 GEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1431



 Score =  143 bits (360), Expect = 5e-34
 Identities = 75/164 (45%), Positives = 88/164 (53%), Gaps = 18/164 (10%)

Query: 456 RGAPGPPGPRGFKGDMGVKGP---VGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG- 511
           +G  G  G  GFKGDMG+KG    VG  GP+G+ G  GP G  GP G PG +G  GE+G 
Sbjct: 789 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 848

Query: 512 --------------PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP 557
                         P G  GFPG  G+ G  G  G  G+PGP+G  GP GP G  G+ GP
Sbjct: 849 LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 908

Query: 558 SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           +G  G  G +G  G PG  G  GP+G  G  G PG  GPPGPPG
Sbjct: 909 TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPG 952



 Score =  142 bits (359), Expect = 7e-34
 Identities = 77/156 (49%), Positives = 92/156 (58%), Gaps = 12/156 (7%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP---LGPQGPQGQPGEAGPVGERGP 512
           RG  GP GP G  GD G++G  G  GP+G PG  GP   LGP+G  G PG+ G  G  GP
Sbjct: 627 RGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP 686

Query: 513 VGPRGFPGLKGSKG---SFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS---GPQGKPGI 566
            GP+G  G +G  G     G  GP+G PGP+G IGPPG +GP G PG +   G  G PG 
Sbjct: 687 PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 746

Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
            GK G  G++GA+GP   PG QGP G PGP G  G+
Sbjct: 747 PGKEGQSGEKGALGP---PGPQGPIGYPGPRGVKGA 779



 Score =  142 bits (359), Expect = 7e-34
 Identities = 83/186 (44%), Positives = 94/186 (50%), Gaps = 39/186 (20%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGG---RGPKGDPGSLGPLGP---QGPQGQPGEAGPVGER 510
            G PGP GP G  G+ G KG +G    +G KGD G  GP GP   QGP G PG AG  GE 
Sbjct: 1123 GLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEP 1182

Query: 511  GP------------VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS 558
            GP             G RGFPG  G  G  G  GP G+ G  GD+GP GP GPPG  GP 
Sbjct: 1183 GPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ 1242

Query: 559  GP---------------------QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP 597
            GP                     +G+PG AG  G PG+ G  GPKGE G +G  G PG  
Sbjct: 1243 GPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAA 1302

Query: 598  GPPGSQ 603
            GPPG++
Sbjct: 1303 GPPGAK 1308



 Score =  141 bits (356), Expect = 2e-33
 Identities = 77/156 (49%), Positives = 91/156 (58%), Gaps = 9/156 (5%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            +GAPG  GP+G  G  GV+GPVG  GP G  GS G  G +G  G+PG+ G  G++G  GP
Sbjct: 1101 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP 1160

Query: 516  RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP------PGSPGPSGPQGKPGIAGK 569
             G PGL+G  G+ G  G  G+PGP+G  G  G +G       PG PGP G QG PG  G+
Sbjct: 1161 PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1220

Query: 570  TGSPGQRGAMGPKGEP---GIQGPPGLPGPPGPPGS 602
             G  G  G MGP G P   G QGP G  GP GPPGS
Sbjct: 1221 KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGS 1256



 Score =  141 bits (356), Expect = 2e-33
 Identities = 77/165 (46%), Positives = 84/165 (50%), Gaps = 18/165 (10%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQ------------PGEA 504
            G PG  GP G KG  G  GP G  GP G PG  GP G  GP GQ            PG+ 
Sbjct: 1297 GPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP 1356

Query: 505  GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564
            GP G  G  GP G PG +G  G+ G  G +G+ G KG+ G  GP G  G  GP GP GKP
Sbjct: 1357 GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1416

Query: 565  ------GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
                  GI G  G  G  GA G  G PG  GPPGLPG  G PGS+
Sbjct: 1417 GPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSK 1461



 Score =  141 bits (355), Expect = 2e-33
 Identities = 72/154 (46%), Positives = 87/154 (56%), Gaps = 6/154 (3%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            + G  G PGPRG +G  G KG  G RG  G PG   P+G QG  G PGE G  G+ GP+G
Sbjct: 1175 IAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG---PIGLQGLPGPPGEKGENGDVGPMG 1231

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574
            P G PG +G +G  G  GP+G PG  G +G  G +G PG  G  GP G+ G+ G  G  G
Sbjct: 1232 PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERG 1291

Query: 575  QRGAMGPKGE---PGIQGPPGLPGPPGPPGSQSF 605
            ++G  GP G    PG +GPPG  GP G PG   F
Sbjct: 1292 EKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1325



 Score =  140 bits (354), Expect = 3e-33
 Identities = 72/156 (46%), Positives = 85/156 (54%), Gaps = 6/156 (3%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G  G PG RG  G  G  G  GG GP+G PG +G  G +G  G  G  G  G  GP GP 
Sbjct: 1036 GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPP 1095

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
            G  G KG+ G  G  GP G+ G +G +G PGP GP GSPG  G +G+ G  G+ GS G +
Sbjct: 1096 GPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDK 1155

Query: 577  GAMGPKGEPGIQGPPGLP------GPPGPPGSQSFY 606
            G  GP G PG+QGP G P      G PGP G Q  +
Sbjct: 1156 GENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMF 1191



 Score =  140 bits (353), Expect = 3e-33
 Identities = 75/148 (50%), Positives = 81/148 (54%), Gaps = 6/148 (4%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G PG PGP G  G  G  G  G +G  GDPG  GP GP G  G PG  G  G  G  G  
Sbjct: 1324 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1383

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGP---PGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
            G  G KG+KG  G  GP G+ GP G  GP   PGPEG  G PGP G QG PG AG+ G P
Sbjct: 1384 GRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1443

Query: 574  GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
               G MGP G PG++G PG  G  G PG
Sbjct: 1444 ---GPMGPPGLPGLKGDPGSKGEKGHPG 1468



 Score =  139 bits (349), Expect = 1e-32
 Identities = 77/171 (45%), Positives = 95/171 (55%), Gaps = 24/171 (14%)

Query: 457 GAPGP------PGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPV 507
           G PGP      PGPRG KG  GV+G  G +G KG+   PG  G +G +G +G+ G+ GP 
Sbjct: 760 GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 819

Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP------PGSPGPSGPQ 561
           GE GP GP+G  G  G  G  G  G +G+ G  G  G PG +GP      PG PG +G +
Sbjct: 820 GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 879

Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP---------GPPGPPGSQ 603
           G  G+AGK G  GQRG  GP+G  G +GP G P         GPPGPPG +
Sbjct: 880 GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 930



 Score =  137 bits (346), Expect = 2e-32
 Identities = 81/169 (47%), Positives = 85/169 (50%), Gaps = 21/169 (12%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGPVG- 508
            RG+ G  GP G  G  G +GP G  G KG PG  GP GP      QGP G PG AGP G 
Sbjct: 1074 RGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1133

Query: 509  --ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGK--- 563
              E G  G  G PG KGSKG  G  GP G PG +G +G PG  G  G PGP G QG    
Sbjct: 1134 PGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQ 1193

Query: 564  ---------PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
                     PG  G  G  G  G  G KGE G  GP G PGPPGP G Q
Sbjct: 1194 KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ 1242



 Score =  137 bits (344), Expect = 4e-32
 Identities = 75/164 (45%), Positives = 88/164 (53%), Gaps = 21/164 (12%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            +G  G  GP G  G +G +GP G  GP+G  G  GP+   G QG PG AG  G  GP+GP
Sbjct: 1392 KGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV---GEQGLPGAAGQDGPPGPMGP 1448

Query: 516  RGFPGLKGSKGS---------FGTGGPRGQPGPKGDIGPPGPEGPPGS---------PGP 557
             G PGLKG  GS          G  GP G+ G KGD G PG +G PG+          GP
Sbjct: 1449 PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGP 1508

Query: 558  SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
             GP G PG+ G  G  G +G+ GP G+ G  G PG PG PGPPG
Sbjct: 1509 LGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1552



 Score =  136 bits (343), Expect = 5e-32
 Identities = 78/174 (44%), Positives = 91/174 (52%), Gaps = 24/174 (13%)

Query: 456 RGAPGPPG------PRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509
           +G PGPPG      P+G  G  G  GP G +GP+G PG  G  G  GP G PG+ G  GE
Sbjct: 696 QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGE 755

Query: 510 RG------PVGPRGFP---------GLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS 554
           +G      P GP G+P         G++G KGS G  G  G PG KGD+G  G  G  G 
Sbjct: 756 KGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQ 815

Query: 555 PGP---SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
            GP    GP+G  G AG TG PG  G  G KG+ G+ G PG PG  GP GS  F
Sbjct: 816 IGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 869



 Score =  133 bits (335), Expect = 4e-31
 Identities = 72/147 (48%), Positives = 83/147 (56%), Gaps = 18/147 (12%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG---PVGERG 511
            LRG PGP G +G  G  G  GP G  GP G PG  G  G +G +G PG  G   P GE+G
Sbjct: 1421 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG 1480

Query: 512  PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTG 571
              G RG PG +GS G+ G GG    PGP G +GPP   GPPG PGP GP+         G
Sbjct: 1481 EKGDRGLPGTQGSPGAKGDGGI---PGPAGPLGPP---GPPGLPGPQGPK---------G 1525

Query: 572  SPGQRGAMGPKGEPGIQGPPGLPGPPG 598
            + G  G  G KG+ G+ GPPG PGPPG
Sbjct: 1526 NKGSTGPAGQKGDSGLPGPPGSPGPPG 1552



 Score =  121 bits (303), Expect = 2e-27
 Identities = 76/193 (39%), Positives = 87/193 (45%), Gaps = 48/193 (24%)

Query: 454 ILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV------ 507
           ++ G PGP GP G  G  G++GP    GP GDPG  GP G  G  G  G  GP       
Sbjct: 451 LVEGPPGPAGPAGIMGPPGLQGPT---GPPGDPGDRGPPGRPGLPGADGLPGPPGTMLML 507

Query: 508 -------GERGP-----------------VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDI 543
                  G +GP                 +  RG PG  G  G  G  G  G  G KG+ 
Sbjct: 508 PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGES 567

Query: 544 GPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR---GAMGPKGEPGIQGPPGLP------ 594
           G PGP+GP G  GP GP GKPG  G+ G+ G R   G  G KG+ G  G PGLP      
Sbjct: 568 GDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHR 627

Query: 595 ------GPPGPPG 601
                 GPPGPPG
Sbjct: 628 GERGPQGPPGPPG 640



 Score =  110 bits (275), Expect = 4e-24
 Identities = 71/183 (38%), Positives = 80/183 (43%), Gaps = 37/183 (20%)

Query: 460 GPPGPRGFKGD-------MGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
           G  G +G KG+       M V+GP G  GP G  G  G  GP GP G PG+ GP G  G 
Sbjct: 432 GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 491

Query: 513 VGPRGFPGLKGSK-------GSFGTGGP--------------------RGQPGPKGDIGP 545
            G  G PG  G+        G  G+ GP                    RG PGP G  G 
Sbjct: 492 PGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGR 551

Query: 546 PGPEGPPGSPGPSGPQGKPGIAGKTG---SPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           PGP G PGS G  G  G PG  G  G    PG  G  G +G PG  G  G+PG PG  G 
Sbjct: 552 PGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGD 611

Query: 603 QSF 605
           + F
Sbjct: 612 RGF 614



 Score =  101 bits (251), Expect = 2e-21
 Identities = 54/120 (45%), Positives = 65/120 (54%), Gaps = 12/120 (10%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G  GPPGP G  G  G+KG  G +G KG PG +G +GP G QG+ G+ G  G +G  G +
Sbjct: 1438 GQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAK 1497

Query: 517  GFPGLKGSKGSFGTGGPRGQPGP------KGDIGPPGPEG------PPGSPGPSGPQGKP 564
            G  G+ G  G  G  GP G PGP      KG  GP G +G      PPGSPGP G   +P
Sbjct: 1498 GDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQP 1557



 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 48/97 (49%), Positives = 53/97 (54%), Gaps = 9/97 (9%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPVGERG 511
            L G  GPPG +G KGD G+ G  G  G KGD   PG  GPLGP GP G PG  GP G +G
Sbjct: 1469 LIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKG 1528

Query: 512  PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548
              GP G       KG  G  GP G PGP G++  P P
Sbjct: 1529 STGPAG------QKGDSGLPGPPGSPGPPGEVIQPLP 1559



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 30/76 (39%), Positives = 34/76 (44%), Gaps = 18/76 (23%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQG------------------P 497
            RG PG  G  G KGD G+ GP G  GP G PG  GP GP+G                  P
Sbjct: 1485 RGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP 1544

Query: 498  QGQPGEAGPVGERGPV 513
             G PG  G V +  P+
Sbjct: 1545 PGSPGPPGEVIQPLPI 1560


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  155 bits (392), Expect = 1e-37
 Identities = 78/156 (50%), Positives = 90/156 (57%), Gaps = 12/156 (7%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            L+G PGPPG +G  GD+G  GP G  GP+G  G  G  GPQGP G  G  G VGE+G  G
Sbjct: 1160 LQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG 1219

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS---PGPSGPQGKPGIAGKTG 571
              G PG     G  G GGP+G+ G KG+ GPPG  GPPG+   PG  GP+G PG  G  G
Sbjct: 1220 EAGNPG---PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPG 1276

Query: 572  SPGQRGAMGPKGEPGI------QGPPGLPGPPGPPG 601
             PG  G  GP G+ G+       G PG PGPPGP G
Sbjct: 1277 DPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSG 1312



 Score =  152 bits (383), Expect = 1e-36
 Identities = 78/147 (53%), Positives = 88/147 (59%), Gaps = 9/147 (6%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            RG PGPPGP    G+ G+ G  G  G KGDP   GP G  G  G  G  G  GERG  G 
Sbjct: 945  RGHPGPPGP---PGEQGLPGAAGKEGAKGDP---GPQGISGKDGPAGLRGFPGERGLPGA 998

Query: 516  RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
            +G PGLKG +G  G  GP G PG +G  G  GP G PG PGP GP   PG AG+ G+PG+
Sbjct: 999  QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGP---PGPAGEKGAPGE 1055

Query: 576  RGAMGPKGEPGIQGPPGLPGPPGPPGS 602
            +G  GP G  G+QGP GLPGP GP GS
Sbjct: 1056 KGPQGPAGRDGVQGPVGLPGPAGPAGS 1082



 Score =  152 bits (383), Expect = 1e-36
 Identities = 78/156 (50%), Positives = 88/156 (56%), Gaps = 12/156 (7%)

Query: 457  GAPGPPGPRGFKGDMGVKGP---------VGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV 507
            G PGPPGPRG +G  G  GP         VGG G KG+PG  G  GP G  G  G  G  
Sbjct: 1180 GPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGER 1239

Query: 508  GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA 567
            GE+G  GP G  G  G+KG  G  GP+G PGP   +G PG  GPPG PGP+G  G  G  
Sbjct: 1240 GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGP---VGFPGDPGPPGEPGPAGQDGVGGDK 1296

Query: 568  GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G+ G PGQ G  GP GE G  GPPG  GPPG  G++
Sbjct: 1297 GEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1332



 Score =  150 bits (380), Expect = 2e-36
 Identities = 78/148 (52%), Positives = 89/148 (60%), Gaps = 9/148 (6%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           RG  G PG  G KG  G +GP G  GP GD G  G  G  GP+G PGEAGP   RG +GP
Sbjct: 561 RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGP---RGLLGP 617

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
           RG PG  G  G  G  GP   PGPKG++GP G  GPPG  G  GPQG PG  G  G PG+
Sbjct: 618 RGTPGAPGQPGMAGVDGP---PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGE 674

Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           +   GP+G+PG+ G PG  GPPG PG +
Sbjct: 675 K---GPQGKPGLAGLPGADGPPGHPGKE 699



 Score =  150 bits (380), Expect = 2e-36
 Identities = 81/167 (48%), Positives = 93/167 (55%), Gaps = 18/167 (10%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLG------PQGPQGQPGEAGPVG 508
            L GA G PG +G +G  G  GPVG  G +G  G+ GP+G      PQGP G  GE G  G
Sbjct: 995  LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1054

Query: 509  ERGPVGPRGFPGLKGSKGSFGTGGPRGQP---GPKGDIGPPGPE---------GPPGSPG 556
            E+GP GP G  G++G  G  G  GP G P   G KG+IG PG +         GPPG PG
Sbjct: 1055 EKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG 1114

Query: 557  PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
              GP G PGIAG  G PG RG  G  G+ G +G  G PGPPGP G Q
Sbjct: 1115 LQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ 1161



 Score =  150 bits (379), Expect = 3e-36
 Identities = 78/160 (48%), Positives = 94/160 (58%), Gaps = 12/160 (7%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVG--GR-------GPKGDPGSLGPLGPQGPQGQPGEAGP 506
            +G PGP G  G +G  G  GP+G  GR       GP G+ G+ G  GPQGP G+ G  GP
Sbjct: 1011 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1070

Query: 507  VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP---EGPPGSPGPSGPQGK 563
            VG  GP GP G PG  G KG  G  G +G  G KG+ GPPGP   +GP G+PG +G  G+
Sbjct: 1071 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGE 1130

Query: 564  PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            PG  G+ G  GQ+G  G +G PG  GP GL G PGPPG +
Sbjct: 1131 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1170



 Score =  149 bits (376), Expect = 7e-36
 Identities = 75/145 (51%), Positives = 85/145 (58%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G  GPPG  G +G  G KG  G  G +G PG  GP+GPQGP G+PG  G  G  GPVG +
Sbjct: 1321 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1380

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
            G PG  G  G  G  GP G PG KGD G  G +G PG  G  GP G+ G  G  G PG +
Sbjct: 1381 GLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1440

Query: 577  GAMGPKGEPGIQGPPGLPGPPGPPG 601
            G+ G KG+ GI GP G  GPPGPPG
Sbjct: 1441 GSPGAKGDGGIPGPAGPLGPPGPPG 1465



 Score =  147 bits (371), Expect = 3e-35
 Identities = 79/168 (47%), Positives = 93/168 (55%), Gaps = 4/168 (2%)

Query: 438 MKAVDTQHGEILRNVTI-LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQG 496
           + A + Q   IL+   I LRG PGP G  G  G +G  G  G +G  GDPG  GP G QG
Sbjct: 470 ISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQG 529

Query: 497 PQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPG 556
           P G  G+ G  G  G  G RG PG  G+KG  G  G  G PG KG  G  GP+GPPG PG
Sbjct: 530 PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 589

Query: 557 PSGPQGKPGIAGKTGSPGQ---RGAMGPKGEPGIQGPPGLPGPPGPPG 601
             G +G+ G  G  G PG+   RG +GP+G PG  G PG+ G  GPPG
Sbjct: 590 DDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 637



 Score =  146 bits (369), Expect = 5e-35
 Identities = 73/146 (50%), Positives = 82/146 (56%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            +G PG  G  G  G+ GV GP G RG KG+ G  G  GP G +G PG+ GP G  GPVG 
Sbjct: 1215 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1274

Query: 516  RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
             G PG  G  G  G  G  G  G  GD G PGP GP G  GP GP GK G  G  G+ G+
Sbjct: 1275 PGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGR 1334

Query: 576  RGAMGPKGEPGIQGPPGLPGPPGPPG 601
            +G  G KGE G +GPPG  GP GP G
Sbjct: 1335 QGEKGAKGEAGAEGPPGKTGPVGPQG 1360



 Score =  145 bits (366), Expect = 1e-34
 Identities = 76/170 (44%), Positives = 90/170 (52%), Gaps = 24/170 (14%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG---ERGP 512
           RG PG PG  G  G  G  GP G  GP+G+PG  G  G  GPQG PG  GP+G   E+GP
Sbjct: 618 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 677

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572
            G  G  GL G+ G  G  G  GQ G KG +GPPGP+GP G PGP G +G  G+ G  GS
Sbjct: 678 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 737

Query: 573 PGQR---------------------GAMGPKGEPGIQGPPGLPGPPGPPG 601
            G++                     G +GP+GE G +GP G  GP G PG
Sbjct: 738 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 787



 Score =  144 bits (364), Expect = 2e-34
 Identities = 84/174 (48%), Positives = 94/174 (54%), Gaps = 27/174 (15%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVG--GR-GPKGD---PGSLGPLGPQGPQGQPGEAGPVGER 510
           G PGP G  G KG +GV G  G  GR GPKG    PG  G  G +G +G  G+ GP G+R
Sbjct: 784 GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 843

Query: 511 GPVGPRGFPGLKGSKGS---FGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP--- 564
           GP GPRG  G +G  G     GT G  G PGP G+ GP GP+GP G PGP GP G P   
Sbjct: 844 GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 903

Query: 565 ------------GIAGKTGSPGQRGAMGPKGEPGIQGP---PGLPGPPGPPGSQ 603
                       G  GKTG PG  G +GP+G  G  GP    G PGPPGPPG Q
Sbjct: 904 GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQ 957



 Score =  144 bits (364), Expect = 2e-34
 Identities = 82/189 (43%), Positives = 93/189 (49%), Gaps = 42/189 (22%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG- 514
            RG  G PGPRG +G  G +G  G RGP G PG  G  G  GP G PGE GP G +GPVG 
Sbjct: 831  RGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGF 890

Query: 515  --PRG---------FPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------PGS 554
              P+G          PG  G +G  G  G  G PGP G +GP GP G          PG 
Sbjct: 891  PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 950

Query: 555  PGPSGPQGKPGIAGKTGS---------------------PGQRGAMGPKGEPGIQGPPGL 593
            PGP G QG PG AGK G+                     PG+RG  G +G PG++G  G 
Sbjct: 951  PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1010

Query: 594  PGPPGPPGS 602
             GPPGP GS
Sbjct: 1011 QGPPGPVGS 1019



 Score =  144 bits (364), Expect = 2e-34
 Identities = 74/150 (49%), Positives = 86/150 (57%), Gaps = 6/150 (4%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            + G  GP G RGF G+ G+ G  G  G KG  G   P GP GP G PGE G  G  GP+G
Sbjct: 977  ISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEG---PQGPPGPVGSPGERGSAGTAGPIG 1033

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP---GIAGKTG 571
              G PG +G  G  G  G  G+ GP+G  G  G +GP G PGP+GP G P   G  G+ G
Sbjct: 1034 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG 1093

Query: 572  SPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
             PGQ+G+ G KGE G  GPPGL GP G PG
Sbjct: 1094 EPGQKGSKGDKGENGPPGPPGLQGPVGAPG 1123



 Score =  144 bits (363), Expect = 2e-34
 Identities = 78/159 (49%), Positives = 87/159 (54%), Gaps = 12/159 (7%)

Query: 457  GAPGPPG------PRGFKGDMGVKGPVGGRGP---KGDPGSLGPLGPQGPQGQPGEAGPV 507
            G PGPPG      P+G +G+ G  GP G  GP   KG PG  GP G  GP G PG+ GP 
Sbjct: 1222 GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP 1281

Query: 508  GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI- 566
            GE GP G  G  G KG  G  G  GP G  G  G  GPPG  GPPG+ G  G QG+ G  
Sbjct: 1282 GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAK 1341

Query: 567  --AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
              AG  G PG+ G +GP+G  G  GP GL G PGP G Q
Sbjct: 1342 GEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1380



 Score =  143 bits (360), Expect = 5e-34
 Identities = 75/164 (45%), Positives = 88/164 (53%), Gaps = 18/164 (10%)

Query: 456 RGAPGPPGPRGFKGDMGVKGP---VGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG- 511
           +G  G  G  GFKGDMG+KG    VG  GP+G+ G  GP G  GP G PG +G  GE+G 
Sbjct: 738 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 797

Query: 512 --------------PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP 557
                         P G  GFPG  G+ G  G  G  G+PGP+G  GP GP G  G+ GP
Sbjct: 798 LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 857

Query: 558 SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           +G  G  G +G  G PG  G  GP+G  G  G PG  GPPGPPG
Sbjct: 858 TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPG 901



 Score =  142 bits (359), Expect = 7e-34
 Identities = 77/156 (49%), Positives = 92/156 (58%), Gaps = 12/156 (7%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP---LGPQGPQGQPGEAGPVGERGP 512
           RG  GP GP G  GD G++G  G  GP+G PG  GP   LGP+G  G PG+ G  G  GP
Sbjct: 576 RGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP 635

Query: 513 VGPRGFPGLKGSKG---SFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS---GPQGKPGI 566
            GP+G  G +G  G     G  GP+G PGP+G IGPPG +GP G PG +   G  G PG 
Sbjct: 636 PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 695

Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
            GK G  G++GA+GP   PG QGP G PGP G  G+
Sbjct: 696 PGKEGQSGEKGALGP---PGPQGPIGYPGPRGVKGA 728



 Score =  142 bits (359), Expect = 7e-34
 Identities = 83/186 (44%), Positives = 94/186 (50%), Gaps = 39/186 (20%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGG---RGPKGDPGSLGPLGP---QGPQGQPGEAGPVGER 510
            G PGP GP G  G+ G KG +G    +G KGD G  GP GP   QGP G PG AG  GE 
Sbjct: 1072 GLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEP 1131

Query: 511  GP------------VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS 558
            GP             G RGFPG  G  G  G  GP G+ G  GD+GP GP GPPG  GP 
Sbjct: 1132 GPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ 1191

Query: 559  GP---------------------QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP 597
            GP                     +G+PG AG  G PG+ G  GPKGE G +G  G PG  
Sbjct: 1192 GPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAA 1251

Query: 598  GPPGSQ 603
            GPPG++
Sbjct: 1252 GPPGAK 1257



 Score =  141 bits (356), Expect = 2e-33
 Identities = 77/156 (49%), Positives = 91/156 (58%), Gaps = 9/156 (5%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            +GAPG  GP+G  G  GV+GPVG  GP G  GS G  G +G  G+PG+ G  G++G  GP
Sbjct: 1050 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP 1109

Query: 516  RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP------PGSPGPSGPQGKPGIAGK 569
             G PGL+G  G+ G  G  G+PGP+G  G  G +G       PG PGP G QG PG  G+
Sbjct: 1110 PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1169

Query: 570  TGSPGQRGAMGPKGEP---GIQGPPGLPGPPGPPGS 602
             G  G  G MGP G P   G QGP G  GP GPPGS
Sbjct: 1170 KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGS 1205



 Score =  141 bits (356), Expect = 2e-33
 Identities = 77/165 (46%), Positives = 84/165 (50%), Gaps = 18/165 (10%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQ------------PGEA 504
            G PG  GP G KG  G  GP G  GP G PG  GP G  GP GQ            PG+ 
Sbjct: 1246 GPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP 1305

Query: 505  GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564
            GP G  G  GP G PG +G  G+ G  G +G+ G KG+ G  GP G  G  GP GP GKP
Sbjct: 1306 GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1365

Query: 565  ------GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
                  GI G  G  G  GA G  G PG  GPPGLPG  G PGS+
Sbjct: 1366 GPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSK 1410



 Score =  141 bits (355), Expect = 2e-33
 Identities = 72/154 (46%), Positives = 87/154 (56%), Gaps = 6/154 (3%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            + G  G PGPRG +G  G KG  G RG  G PG   P+G QG  G PGE G  G+ GP+G
Sbjct: 1124 IAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG---PIGLQGLPGPPGEKGENGDVGPMG 1180

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574
            P G PG +G +G  G  GP+G PG  G +G  G +G PG  G  GP G+ G+ G  G  G
Sbjct: 1181 PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERG 1240

Query: 575  QRGAMGPKGE---PGIQGPPGLPGPPGPPGSQSF 605
            ++G  GP G    PG +GPPG  GP G PG   F
Sbjct: 1241 EKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1274



 Score =  140 bits (354), Expect = 3e-33
 Identities = 72/156 (46%), Positives = 85/156 (54%), Gaps = 6/156 (3%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G  G PG RG  G  G  G  GG GP+G PG +G  G +G  G  G  G  G  GP GP 
Sbjct: 985  GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPP 1044

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
            G  G KG+ G  G  GP G+ G +G +G PGP GP GSPG  G +G+ G  G+ GS G +
Sbjct: 1045 GPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDK 1104

Query: 577  GAMGPKGEPGIQGPPGLP------GPPGPPGSQSFY 606
            G  GP G PG+QGP G P      G PGP G Q  +
Sbjct: 1105 GENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMF 1140



 Score =  140 bits (353), Expect = 3e-33
 Identities = 75/148 (50%), Positives = 81/148 (54%), Gaps = 6/148 (4%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G PG PGP G  G  G  G  G +G  GDPG  GP GP G  G PG  G  G  G  G  
Sbjct: 1273 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1332

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGP---PGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
            G  G KG+KG  G  GP G+ GP G  GP   PGPEG  G PGP G QG PG AG+ G P
Sbjct: 1333 GRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1392

Query: 574  GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
               G MGP G PG++G PG  G  G PG
Sbjct: 1393 ---GPMGPPGLPGLKGDPGSKGEKGHPG 1417



 Score =  139 bits (349), Expect = 1e-32
 Identities = 77/171 (45%), Positives = 95/171 (55%), Gaps = 24/171 (14%)

Query: 457 GAPGP------PGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPV 507
           G PGP      PGPRG KG  GV+G  G +G KG+   PG  G +G +G +G+ G+ GP 
Sbjct: 709 GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 768

Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP------PGSPGPSGPQ 561
           GE GP GP+G  G  G  G  G  G +G+ G  G  G PG +GP      PG PG +G +
Sbjct: 769 GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 828

Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP---------GPPGPPGSQ 603
           G  G+AGK G  GQRG  GP+G  G +GP G P         GPPGPPG +
Sbjct: 829 GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 879



 Score =  137 bits (346), Expect = 2e-32
 Identities = 81/169 (47%), Positives = 85/169 (50%), Gaps = 21/169 (12%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGPVG- 508
            RG+ G  GP G  G  G +GP G  G KG PG  GP GP      QGP G PG AGP G 
Sbjct: 1023 RGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1082

Query: 509  --ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGK--- 563
              E G  G  G PG KGSKG  G  GP G PG +G +G PG  G  G PGP G QG    
Sbjct: 1083 PGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQ 1142

Query: 564  ---------PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
                     PG  G  G  G  G  G KGE G  GP G PGPPGP G Q
Sbjct: 1143 KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ 1191



 Score =  137 bits (344), Expect = 4e-32
 Identities = 75/164 (45%), Positives = 88/164 (53%), Gaps = 21/164 (12%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            +G  G  GP G  G +G +GP G  GP+G  G  GP+   G QG PG AG  G  GP+GP
Sbjct: 1341 KGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV---GEQGLPGAAGQDGPPGPMGP 1397

Query: 516  RGFPGLKGSKGS---------FGTGGPRGQPGPKGDIGPPGPEGPPGS---------PGP 557
             G PGLKG  GS          G  GP G+ G KGD G PG +G PG+          GP
Sbjct: 1398 PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGP 1457

Query: 558  SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
             GP G PG+ G  G  G +G+ GP G+ G  G PG PG PGPPG
Sbjct: 1458 LGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1501



 Score =  136 bits (343), Expect = 5e-32
 Identities = 78/174 (44%), Positives = 91/174 (52%), Gaps = 24/174 (13%)

Query: 456 RGAPGPPG------PRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509
           +G PGPPG      P+G  G  G  GP G +GP+G PG  G  G  GP G PG+ G  GE
Sbjct: 645 QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGE 704

Query: 510 RG------PVGPRGFP---------GLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS 554
           +G      P GP G+P         G++G KGS G  G  G PG KGD+G  G  G  G 
Sbjct: 705 KGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQ 764

Query: 555 PGP---SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
            GP    GP+G  G AG TG PG  G  G KG+ G+ G PG PG  GP GS  F
Sbjct: 765 IGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 818



 Score =  133 bits (335), Expect = 4e-31
 Identities = 72/147 (48%), Positives = 83/147 (56%), Gaps = 18/147 (12%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG---PVGERG 511
            LRG PGP G +G  G  G  GP G  GP G PG  G  G +G +G PG  G   P GE+G
Sbjct: 1370 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG 1429

Query: 512  PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTG 571
              G RG PG +GS G+ G GG    PGP G +GPP   GPPG PGP GP+         G
Sbjct: 1430 EKGDRGLPGTQGSPGAKGDGGI---PGPAGPLGPP---GPPGLPGPQGPK---------G 1474

Query: 572  SPGQRGAMGPKGEPGIQGPPGLPGPPG 598
            + G  G  G KG+ G+ GPPG PGPPG
Sbjct: 1475 NKGSTGPAGQKGDSGLPGPPGSPGPPG 1501



 Score =  121 bits (303), Expect = 2e-27
 Identities = 76/193 (39%), Positives = 87/193 (45%), Gaps = 48/193 (24%)

Query: 454 ILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV------ 507
           ++ G PGP GP G  G  G++GP    GP GDPG  GP G  G  G  G  GP       
Sbjct: 400 LVEGPPGPAGPAGIMGPPGLQGPT---GPPGDPGDRGPPGRPGLPGADGLPGPPGTMLML 456

Query: 508 -------GERGP-----------------VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDI 543
                  G +GP                 +  RG PG  G  G  G  G  G  G KG+ 
Sbjct: 457 PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGES 516

Query: 544 GPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR---GAMGPKGEPGIQGPPGLP------ 594
           G PGP+GP G  GP GP GKPG  G+ G+ G R   G  G KG+ G  G PGLP      
Sbjct: 517 GDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHR 576

Query: 595 ------GPPGPPG 601
                 GPPGPPG
Sbjct: 577 GERGPQGPPGPPG 589



 Score =  110 bits (275), Expect = 4e-24
 Identities = 71/183 (38%), Positives = 80/183 (43%), Gaps = 37/183 (20%)

Query: 460 GPPGPRGFKGD-------MGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
           G  G +G KG+       M V+GP G  GP G  G  G  GP GP G PG+ GP G  G 
Sbjct: 381 GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 440

Query: 513 VGPRGFPGLKGSK-------GSFGTGGP--------------------RGQPGPKGDIGP 545
            G  G PG  G+        G  G+ GP                    RG PGP G  G 
Sbjct: 441 PGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGR 500

Query: 546 PGPEGPPGSPGPSGPQGKPGIAGKTG---SPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           PGP G PGS G  G  G PG  G  G    PG  G  G +G PG  G  G+PG PG  G 
Sbjct: 501 PGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGD 560

Query: 603 QSF 605
           + F
Sbjct: 561 RGF 563



 Score =  101 bits (251), Expect = 2e-21
 Identities = 54/120 (45%), Positives = 65/120 (54%), Gaps = 12/120 (10%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G  GPPGP G  G  G+KG  G +G KG PG +G +GP G QG+ G+ G  G +G  G +
Sbjct: 1387 GQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAK 1446

Query: 517  GFPGLKGSKGSFGTGGPRGQPGP------KGDIGPPGPEG------PPGSPGPSGPQGKP 564
            G  G+ G  G  G  GP G PGP      KG  GP G +G      PPGSPGP G   +P
Sbjct: 1447 GDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQP 1506



 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 48/97 (49%), Positives = 53/97 (54%), Gaps = 9/97 (9%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPVGERG 511
            L G  GPPG +G KGD G+ G  G  G KGD   PG  GPLGP GP G PG  GP G +G
Sbjct: 1418 LIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKG 1477

Query: 512  PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548
              GP G       KG  G  GP G PGP G++  P P
Sbjct: 1478 STGPAG------QKGDSGLPGPPGSPGPPGEVIQPLP 1508



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 30/76 (39%), Positives = 34/76 (44%), Gaps = 18/76 (23%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQG------------------P 497
            RG PG  G  G KGD G+ GP G  GP G PG  GP GP+G                  P
Sbjct: 1434 RGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP 1493

Query: 498  QGQPGEAGPVGERGPV 513
             G PG  G V +  P+
Sbjct: 1494 PGSPGPPGEVIQPLPI 1509


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  155 bits (392), Expect = 1e-37
 Identities = 78/156 (50%), Positives = 90/156 (57%), Gaps = 12/156 (7%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            L+G PGPPG +G  GD+G  GP G  GP+G  G  G  GPQGP G  G  G VGE+G  G
Sbjct: 1199 LQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG 1258

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS---PGPSGPQGKPGIAGKTG 571
              G PG     G  G GGP+G+ G KG+ GPPG  GPPG+   PG  GP+G PG  G  G
Sbjct: 1259 EAGNPG---PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPG 1315

Query: 572  SPGQRGAMGPKGEPGI------QGPPGLPGPPGPPG 601
             PG  G  GP G+ G+       G PG PGPPGP G
Sbjct: 1316 DPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSG 1351



 Score =  152 bits (383), Expect = 1e-36
 Identities = 78/147 (53%), Positives = 88/147 (59%), Gaps = 9/147 (6%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            RG PGPPGP    G+ G+ G  G  G KGDP   GP G  G  G  G  G  GERG  G 
Sbjct: 984  RGHPGPPGP---PGEQGLPGAAGKEGAKGDP---GPQGISGKDGPAGLRGFPGERGLPGA 1037

Query: 516  RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
            +G PGLKG +G  G  GP G PG +G  G  GP G PG PGP GP   PG AG+ G+PG+
Sbjct: 1038 QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGP---PGPAGEKGAPGE 1094

Query: 576  RGAMGPKGEPGIQGPPGLPGPPGPPGS 602
            +G  GP G  G+QGP GLPGP GP GS
Sbjct: 1095 KGPQGPAGRDGVQGPVGLPGPAGPAGS 1121



 Score =  152 bits (383), Expect = 1e-36
 Identities = 78/156 (50%), Positives = 88/156 (56%), Gaps = 12/156 (7%)

Query: 457  GAPGPPGPRGFKGDMGVKGP---------VGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV 507
            G PGPPGPRG +G  G  GP         VGG G KG+PG  G  GP G  G  G  G  
Sbjct: 1219 GPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGER 1278

Query: 508  GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA 567
            GE+G  GP G  G  G+KG  G  GP+G PGP   +G PG  GPPG PGP+G  G  G  
Sbjct: 1279 GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGP---VGFPGDPGPPGEPGPAGQDGVGGDK 1335

Query: 568  GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G+ G PGQ G  GP GE G  GPPG  GPPG  G++
Sbjct: 1336 GEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1371



 Score =  150 bits (380), Expect = 2e-36
 Identities = 78/148 (52%), Positives = 89/148 (60%), Gaps = 9/148 (6%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           RG  G PG  G KG  G +GP G  GP GD G  G  G  GP+G PGEAGP   RG +GP
Sbjct: 600 RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGP---RGLLGP 656

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
           RG PG  G  G  G  GP   PGPKG++GP G  GPPG  G  GPQG PG  G  G PG+
Sbjct: 657 RGTPGAPGQPGMAGVDGP---PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGE 713

Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           +   GP+G+PG+ G PG  GPPG PG +
Sbjct: 714 K---GPQGKPGLAGLPGADGPPGHPGKE 738



 Score =  150 bits (380), Expect = 2e-36
 Identities = 81/167 (48%), Positives = 93/167 (55%), Gaps = 18/167 (10%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLG------PQGPQGQPGEAGPVG 508
            L GA G PG +G +G  G  GPVG  G +G  G+ GP+G      PQGP G  GE G  G
Sbjct: 1034 LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1093

Query: 509  ERGPVGPRGFPGLKGSKGSFGTGGPRGQP---GPKGDIGPPGPE---------GPPGSPG 556
            E+GP GP G  G++G  G  G  GP G P   G KG+IG PG +         GPPG PG
Sbjct: 1094 EKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG 1153

Query: 557  PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
              GP G PGIAG  G PG RG  G  G+ G +G  G PGPPGP G Q
Sbjct: 1154 LQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ 1200



 Score =  150 bits (379), Expect = 3e-36
 Identities = 78/160 (48%), Positives = 94/160 (58%), Gaps = 12/160 (7%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVG--GR-------GPKGDPGSLGPLGPQGPQGQPGEAGP 506
            +G PGP G  G +G  G  GP+G  GR       GP G+ G+ G  GPQGP G+ G  GP
Sbjct: 1050 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1109

Query: 507  VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP---EGPPGSPGPSGPQGK 563
            VG  GP GP G PG  G KG  G  G +G  G KG+ GPPGP   +GP G+PG +G  G+
Sbjct: 1110 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGE 1169

Query: 564  PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            PG  G+ G  GQ+G  G +G PG  GP GL G PGPPG +
Sbjct: 1170 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1209



 Score =  149 bits (376), Expect = 7e-36
 Identities = 75/145 (51%), Positives = 85/145 (58%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G  GPPG  G +G  G KG  G  G +G PG  GP+GPQGP G+PG  G  G  GPVG +
Sbjct: 1360 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1419

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
            G PG  G  G  G  GP G PG KGD G  G +G PG  G  GP G+ G  G  G PG +
Sbjct: 1420 GLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1479

Query: 577  GAMGPKGEPGIQGPPGLPGPPGPPG 601
            G+ G KG+ GI GP G  GPPGPPG
Sbjct: 1480 GSPGAKGDGGIPGPAGPLGPPGPPG 1504



 Score =  147 bits (371), Expect = 3e-35
 Identities = 79/168 (47%), Positives = 93/168 (55%), Gaps = 4/168 (2%)

Query: 438 MKAVDTQHGEILRNVTI-LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQG 496
           + A + Q   IL+   I LRG PGP G  G  G +G  G  G +G  GDPG  GP G QG
Sbjct: 509 ISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQG 568

Query: 497 PQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPG 556
           P G  G+ G  G  G  G RG PG  G+KG  G  G  G PG KG  G  GP+GPPG PG
Sbjct: 569 PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 628

Query: 557 PSGPQGKPGIAGKTGSPGQ---RGAMGPKGEPGIQGPPGLPGPPGPPG 601
             G +G+ G  G  G PG+   RG +GP+G PG  G PG+ G  GPPG
Sbjct: 629 DDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 676



 Score =  146 bits (369), Expect = 5e-35
 Identities = 73/146 (50%), Positives = 82/146 (56%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            +G PG  G  G  G+ GV GP G RG KG+ G  G  GP G +G PG+ GP G  GPVG 
Sbjct: 1254 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1313

Query: 516  RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
             G PG  G  G  G  G  G  G  GD G PGP GP G  GP GP GK G  G  G+ G+
Sbjct: 1314 PGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGR 1373

Query: 576  RGAMGPKGEPGIQGPPGLPGPPGPPG 601
            +G  G KGE G +GPPG  GP GP G
Sbjct: 1374 QGEKGAKGEAGAEGPPGKTGPVGPQG 1399



 Score =  145 bits (366), Expect = 1e-34
 Identities = 76/170 (44%), Positives = 90/170 (52%), Gaps = 24/170 (14%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG---ERGP 512
           RG PG PG  G  G  G  GP G  GP+G+PG  G  G  GPQG PG  GP+G   E+GP
Sbjct: 657 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 716

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572
            G  G  GL G+ G  G  G  GQ G KG +GPPGP+GP G PGP G +G  G+ G  GS
Sbjct: 717 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 776

Query: 573 PGQR---------------------GAMGPKGEPGIQGPPGLPGPPGPPG 601
            G++                     G +GP+GE G +GP G  GP G PG
Sbjct: 777 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 826



 Score =  144 bits (364), Expect = 2e-34
 Identities = 84/174 (48%), Positives = 94/174 (54%), Gaps = 27/174 (15%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVG--GR-GPKGD---PGSLGPLGPQGPQGQPGEAGPVGER 510
           G PGP G  G KG +GV G  G  GR GPKG    PG  G  G +G +G  G+ GP G+R
Sbjct: 823 GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 882

Query: 511 GPVGPRGFPGLKGSKGS---FGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP--- 564
           GP GPRG  G +G  G     GT G  G PGP G+ GP GP+GP G PGP GP G P   
Sbjct: 883 GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 942

Query: 565 ------------GIAGKTGSPGQRGAMGPKGEPGIQGP---PGLPGPPGPPGSQ 603
                       G  GKTG PG  G +GP+G  G  GP    G PGPPGPPG Q
Sbjct: 943 GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQ 996



 Score =  144 bits (364), Expect = 2e-34
 Identities = 82/189 (43%), Positives = 93/189 (49%), Gaps = 42/189 (22%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG- 514
            RG  G PGPRG +G  G +G  G RGP G PG  G  G  GP G PGE GP G +GPVG 
Sbjct: 870  RGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGF 929

Query: 515  --PRG---------FPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------PGS 554
              P+G          PG  G +G  G  G  G PGP G +GP GP G          PG 
Sbjct: 930  PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 989

Query: 555  PGPSGPQGKPGIAGKTGS---------------------PGQRGAMGPKGEPGIQGPPGL 593
            PGP G QG PG AGK G+                     PG+RG  G +G PG++G  G 
Sbjct: 990  PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1049

Query: 594  PGPPGPPGS 602
             GPPGP GS
Sbjct: 1050 QGPPGPVGS 1058



 Score =  144 bits (364), Expect = 2e-34
 Identities = 74/150 (49%), Positives = 86/150 (57%), Gaps = 6/150 (4%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            + G  GP G RGF G+ G+ G  G  G KG  G   P GP GP G PGE G  G  GP+G
Sbjct: 1016 ISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEG---PQGPPGPVGSPGERGSAGTAGPIG 1072

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP---GIAGKTG 571
              G PG +G  G  G  G  G+ GP+G  G  G +GP G PGP+GP G P   G  G+ G
Sbjct: 1073 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG 1132

Query: 572  SPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
             PGQ+G+ G KGE G  GPPGL GP G PG
Sbjct: 1133 EPGQKGSKGDKGENGPPGPPGLQGPVGAPG 1162



 Score =  144 bits (363), Expect = 2e-34
 Identities = 78/159 (49%), Positives = 87/159 (54%), Gaps = 12/159 (7%)

Query: 457  GAPGPPG------PRGFKGDMGVKGPVGGRGP---KGDPGSLGPLGPQGPQGQPGEAGPV 507
            G PGPPG      P+G +G+ G  GP G  GP   KG PG  GP G  GP G PG+ GP 
Sbjct: 1261 GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP 1320

Query: 508  GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI- 566
            GE GP G  G  G KG  G  G  GP G  G  G  GPPG  GPPG+ G  G QG+ G  
Sbjct: 1321 GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAK 1380

Query: 567  --AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
              AG  G PG+ G +GP+G  G  GP GL G PGP G Q
Sbjct: 1381 GEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1419



 Score =  143 bits (360), Expect = 5e-34
 Identities = 75/164 (45%), Positives = 88/164 (53%), Gaps = 18/164 (10%)

Query: 456 RGAPGPPGPRGFKGDMGVKGP---VGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG- 511
           +G  G  G  GFKGDMG+KG    VG  GP+G+ G  GP G  GP G PG +G  GE+G 
Sbjct: 777 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 836

Query: 512 --------------PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP 557
                         P G  GFPG  G+ G  G  G  G+PGP+G  GP GP G  G+ GP
Sbjct: 837 LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 896

Query: 558 SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           +G  G  G +G  G PG  G  GP+G  G  G PG  GPPGPPG
Sbjct: 897 TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPG 940



 Score =  142 bits (359), Expect = 7e-34
 Identities = 77/156 (49%), Positives = 92/156 (58%), Gaps = 12/156 (7%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP---LGPQGPQGQPGEAGPVGERGP 512
           RG  GP GP G  GD G++G  G  GP+G PG  GP   LGP+G  G PG+ G  G  GP
Sbjct: 615 RGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP 674

Query: 513 VGPRGFPGLKGSKG---SFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS---GPQGKPGI 566
            GP+G  G +G  G     G  GP+G PGP+G IGPPG +GP G PG +   G  G PG 
Sbjct: 675 PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 734

Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
            GK G  G++GA+GP   PG QGP G PGP G  G+
Sbjct: 735 PGKEGQSGEKGALGP---PGPQGPIGYPGPRGVKGA 767



 Score =  142 bits (359), Expect = 7e-34
 Identities = 83/186 (44%), Positives = 94/186 (50%), Gaps = 39/186 (20%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGG---RGPKGDPGSLGPLGP---QGPQGQPGEAGPVGER 510
            G PGP GP G  G+ G KG +G    +G KGD G  GP GP   QGP G PG AG  GE 
Sbjct: 1111 GLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEP 1170

Query: 511  GP------------VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS 558
            GP             G RGFPG  G  G  G  GP G+ G  GD+GP GP GPPG  GP 
Sbjct: 1171 GPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ 1230

Query: 559  GP---------------------QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP 597
            GP                     +G+PG AG  G PG+ G  GPKGE G +G  G PG  
Sbjct: 1231 GPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAA 1290

Query: 598  GPPGSQ 603
            GPPG++
Sbjct: 1291 GPPGAK 1296



 Score =  141 bits (356), Expect = 2e-33
 Identities = 77/156 (49%), Positives = 91/156 (58%), Gaps = 9/156 (5%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            +GAPG  GP+G  G  GV+GPVG  GP G  GS G  G +G  G+PG+ G  G++G  GP
Sbjct: 1089 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP 1148

Query: 516  RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP------PGSPGPSGPQGKPGIAGK 569
             G PGL+G  G+ G  G  G+PGP+G  G  G +G       PG PGP G QG PG  G+
Sbjct: 1149 PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1208

Query: 570  TGSPGQRGAMGPKGEP---GIQGPPGLPGPPGPPGS 602
             G  G  G MGP G P   G QGP G  GP GPPGS
Sbjct: 1209 KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGS 1244



 Score =  141 bits (356), Expect = 2e-33
 Identities = 77/165 (46%), Positives = 84/165 (50%), Gaps = 18/165 (10%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQ------------PGEA 504
            G PG  GP G KG  G  GP G  GP G PG  GP G  GP GQ            PG+ 
Sbjct: 1285 GPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP 1344

Query: 505  GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564
            GP G  G  GP G PG +G  G+ G  G +G+ G KG+ G  GP G  G  GP GP GKP
Sbjct: 1345 GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1404

Query: 565  ------GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
                  GI G  G  G  GA G  G PG  GPPGLPG  G PGS+
Sbjct: 1405 GPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSK 1449



 Score =  141 bits (355), Expect = 2e-33
 Identities = 72/154 (46%), Positives = 87/154 (56%), Gaps = 6/154 (3%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            + G  G PGPRG +G  G KG  G RG  G PG   P+G QG  G PGE G  G+ GP+G
Sbjct: 1163 IAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG---PIGLQGLPGPPGEKGENGDVGPMG 1219

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574
            P G PG +G +G  G  GP+G PG  G +G  G +G PG  G  GP G+ G+ G  G  G
Sbjct: 1220 PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERG 1279

Query: 575  QRGAMGPKGE---PGIQGPPGLPGPPGPPGSQSF 605
            ++G  GP G    PG +GPPG  GP G PG   F
Sbjct: 1280 EKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1313



 Score =  140 bits (354), Expect = 3e-33
 Identities = 72/156 (46%), Positives = 85/156 (54%), Gaps = 6/156 (3%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G  G PG RG  G  G  G  GG GP+G PG +G  G +G  G  G  G  G  GP GP 
Sbjct: 1024 GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPP 1083

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
            G  G KG+ G  G  GP G+ G +G +G PGP GP GSPG  G +G+ G  G+ GS G +
Sbjct: 1084 GPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDK 1143

Query: 577  GAMGPKGEPGIQGPPGLP------GPPGPPGSQSFY 606
            G  GP G PG+QGP G P      G PGP G Q  +
Sbjct: 1144 GENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMF 1179



 Score =  140 bits (353), Expect = 3e-33
 Identities = 75/148 (50%), Positives = 81/148 (54%), Gaps = 6/148 (4%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G PG PGP G  G  G  G  G +G  GDPG  GP GP G  G PG  G  G  G  G  
Sbjct: 1312 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1371

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGP---PGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
            G  G KG+KG  G  GP G+ GP G  GP   PGPEG  G PGP G QG PG AG+ G P
Sbjct: 1372 GRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1431

Query: 574  GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
               G MGP G PG++G PG  G  G PG
Sbjct: 1432 ---GPMGPPGLPGLKGDPGSKGEKGHPG 1456



 Score =  139 bits (349), Expect = 1e-32
 Identities = 77/171 (45%), Positives = 95/171 (55%), Gaps = 24/171 (14%)

Query: 457 GAPGP------PGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPV 507
           G PGP      PGPRG KG  GV+G  G +G KG+   PG  G +G +G +G+ G+ GP 
Sbjct: 748 GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 807

Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP------PGSPGPSGPQ 561
           GE GP GP+G  G  G  G  G  G +G+ G  G  G PG +GP      PG PG +G +
Sbjct: 808 GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 867

Query: 562 GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP---------GPPGPPGSQ 603
           G  G+AGK G  GQRG  GP+G  G +GP G P         GPPGPPG +
Sbjct: 868 GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 918



 Score =  137 bits (346), Expect = 2e-32
 Identities = 81/169 (47%), Positives = 85/169 (50%), Gaps = 21/169 (12%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGPVG- 508
            RG+ G  GP G  G  G +GP G  G KG PG  GP GP      QGP G PG AGP G 
Sbjct: 1062 RGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1121

Query: 509  --ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGK--- 563
              E G  G  G PG KGSKG  G  GP G PG +G +G PG  G  G PGP G QG    
Sbjct: 1122 PGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQ 1181

Query: 564  ---------PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
                     PG  G  G  G  G  G KGE G  GP G PGPPGP G Q
Sbjct: 1182 KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ 1230



 Score =  137 bits (344), Expect = 4e-32
 Identities = 75/164 (45%), Positives = 88/164 (53%), Gaps = 21/164 (12%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            +G  G  GP G  G +G +GP G  GP+G  G  GP+   G QG PG AG  G  GP+GP
Sbjct: 1380 KGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV---GEQGLPGAAGQDGPPGPMGP 1436

Query: 516  RGFPGLKGSKGS---------FGTGGPRGQPGPKGDIGPPGPEGPPGS---------PGP 557
             G PGLKG  GS          G  GP G+ G KGD G PG +G PG+          GP
Sbjct: 1437 PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGP 1496

Query: 558  SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
             GP G PG+ G  G  G +G+ GP G+ G  G PG PG PGPPG
Sbjct: 1497 LGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1540



 Score =  136 bits (343), Expect = 5e-32
 Identities = 78/174 (44%), Positives = 91/174 (52%), Gaps = 24/174 (13%)

Query: 456 RGAPGPPG------PRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509
           +G PGPPG      P+G  G  G  GP G +GP+G PG  G  G  GP G PG+ G  GE
Sbjct: 684 QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGE 743

Query: 510 RG------PVGPRGFP---------GLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS 554
           +G      P GP G+P         G++G KGS G  G  G PG KGD+G  G  G  G 
Sbjct: 744 KGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQ 803

Query: 555 PGP---SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
            GP    GP+G  G AG TG PG  G  G KG+ G+ G PG PG  GP GS  F
Sbjct: 804 IGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 857



 Score =  133 bits (335), Expect = 4e-31
 Identities = 72/147 (48%), Positives = 83/147 (56%), Gaps = 18/147 (12%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG---PVGERG 511
            LRG PGP G +G  G  G  GP G  GP G PG  G  G +G +G PG  G   P GE+G
Sbjct: 1409 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG 1468

Query: 512  PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTG 571
              G RG PG +GS G+ G GG    PGP G +GPP   GPPG PGP GP+         G
Sbjct: 1469 EKGDRGLPGTQGSPGAKGDGGI---PGPAGPLGPP---GPPGLPGPQGPK---------G 1513

Query: 572  SPGQRGAMGPKGEPGIQGPPGLPGPPG 598
            + G  G  G KG+ G+ GPPG PGPPG
Sbjct: 1514 NKGSTGPAGQKGDSGLPGPPGSPGPPG 1540



 Score =  121 bits (303), Expect = 2e-27
 Identities = 76/193 (39%), Positives = 87/193 (45%), Gaps = 48/193 (24%)

Query: 454 ILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV------ 507
           ++ G PGP GP G  G  G++GP    GP GDPG  GP G  G  G  G  GP       
Sbjct: 439 LVEGPPGPAGPAGIMGPPGLQGPT---GPPGDPGDRGPPGRPGLPGADGLPGPPGTMLML 495

Query: 508 -------GERGP-----------------VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDI 543
                  G +GP                 +  RG PG  G  G  G  G  G  G KG+ 
Sbjct: 496 PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGES 555

Query: 544 GPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR---GAMGPKGEPGIQGPPGLP------ 594
           G PGP+GP G  GP GP GKPG  G+ G+ G R   G  G KG+ G  G PGLP      
Sbjct: 556 GDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHR 615

Query: 595 ------GPPGPPG 601
                 GPPGPPG
Sbjct: 616 GERGPQGPPGPPG 628



 Score =  110 bits (275), Expect = 4e-24
 Identities = 71/183 (38%), Positives = 80/183 (43%), Gaps = 37/183 (20%)

Query: 460 GPPGPRGFKGD-------MGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
           G  G +G KG+       M V+GP G  GP G  G  G  GP GP G PG+ GP G  G 
Sbjct: 420 GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 479

Query: 513 VGPRGFPGLKGSK-------GSFGTGGP--------------------RGQPGPKGDIGP 545
            G  G PG  G+        G  G+ GP                    RG PGP G  G 
Sbjct: 480 PGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGR 539

Query: 546 PGPEGPPGSPGPSGPQGKPGIAGKTG---SPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           PGP G PGS G  G  G PG  G  G    PG  G  G +G PG  G  G+PG PG  G 
Sbjct: 540 PGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGD 599

Query: 603 QSF 605
           + F
Sbjct: 600 RGF 602



 Score =  101 bits (251), Expect = 2e-21
 Identities = 54/120 (45%), Positives = 65/120 (54%), Gaps = 12/120 (10%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G  GPPGP G  G  G+KG  G +G KG PG +G +GP G QG+ G+ G  G +G  G +
Sbjct: 1426 GQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAK 1485

Query: 517  GFPGLKGSKGSFGTGGPRGQPGP------KGDIGPPGPEG------PPGSPGPSGPQGKP 564
            G  G+ G  G  G  GP G PGP      KG  GP G +G      PPGSPGP G   +P
Sbjct: 1486 GDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQP 1545



 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 48/97 (49%), Positives = 53/97 (54%), Gaps = 9/97 (9%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGPQGPQGQPGEAGPVGERG 511
            L G  GPPG +G KGD G+ G  G  G KGD   PG  GPLGP GP G PG  GP G +G
Sbjct: 1457 LIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKG 1516

Query: 512  PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548
              GP G       KG  G  GP G PGP G++  P P
Sbjct: 1517 STGPAG------QKGDSGLPGPPGSPGPPGEVIQPLP 1547



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 30/76 (39%), Positives = 34/76 (44%), Gaps = 18/76 (23%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQG------------------P 497
            RG PG  G  G KGD G+ GP G  GP G PG  GP GP+G                  P
Sbjct: 1473 RGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP 1532

Query: 498  QGQPGEAGPVGERGPV 513
             G PG  G V +  P+
Sbjct: 1533 PGSPGPPGEVIQPLPI 1548


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score =  155 bits (392), Expect = 1e-37
 Identities = 76/146 (52%), Positives = 86/146 (58%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            +GAPG PGP G  GD G +G  G RGP G PG  G  G  GPQG  G+ G  G+RG  G 
Sbjct: 1082 QGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQ 1141

Query: 516  RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
            +G  G  G +G  G  GP G+ G  G  GP GP GPPG  GPSG +G PG  G  G PG 
Sbjct: 1142 KGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGV 1201

Query: 576  RGAMGPKGEPGIQGPPGLPGPPGPPG 601
            RG++G  G  G  G PG PGPPGPPG
Sbjct: 1202 RGSVGEAGPEGPPGEPGPPGPPGPPG 1227



 Score =  150 bits (380), Expect = 2e-36
 Identities = 78/162 (48%), Positives = 90/162 (55%), Gaps = 15/162 (9%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
           + G PGP G RG  G+ G +G  G  G +G PG LGP GP GP G+ GE GP G  GP G
Sbjct: 769 IAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPG 828

Query: 515 PRGFPGLKGSKG---SFGTGGPRG------------QPGPKGDIGPPGPEGPPGSPGPSG 559
            RG PG +G  G   + G  GP+G            +PG KGD G PGP+G  GSPGP G
Sbjct: 829 SRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHG 888

Query: 560 PQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           P G PG+ G  G+ G  GA G  G  G  GPPG  G PGP G
Sbjct: 889 PNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAG 930



 Score =  150 bits (380), Expect = 2e-36
 Identities = 78/155 (50%), Positives = 87/155 (56%), Gaps = 9/155 (5%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G PG  GP G +GD G  G VG RGP G PG  G  G  G  GQPG  GP G  G  G R
Sbjct: 933  GEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQR 992

Query: 517  GF---PGLKGSKGSFGTGGPRGQPGP------KGDIGPPGPEGPPGSPGPSGPQGKPGIA 567
            G    PG +G +G  G  GP G PG        GD GPPGP GPPGS GP G  G  G A
Sbjct: 993  GIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPA 1052

Query: 568  GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
            G  G+PG+ GA+G +G+ G  GP GLPG  G PG+
Sbjct: 1053 GNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGT 1087



 Score =  150 bits (379), Expect = 3e-36
 Identities = 80/160 (50%), Positives = 85/160 (53%), Gaps = 12/160 (7%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            L G+PGP GP G  G  G +G  G  G  G PGS G +GP GP G PG AGP+GE G  G
Sbjct: 880  LAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEG 939

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574
            P G  G  GS G  G  GP G PG  GD G PG +G PG  GP GP G  G  G  G PG
Sbjct: 940  PPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPG 999

Query: 575  QRGAMGPKGEPGIQGPPGL------------PGPPGPPGS 602
            QRG  G  G PG  G PG             PGP GPPGS
Sbjct: 1000 QRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGS 1039



 Score =  150 bits (378), Expect = 4e-36
 Identities = 76/147 (51%), Positives = 85/147 (57%), Gaps = 6/147 (4%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           GAPG  G  G  G MG  GP+G   P+G PG  G LGPQG  GQ G  G  G+ GP+GP 
Sbjct: 315 GAPGSKGEAGPTGPMGAMGPLG---PRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPL 371

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           G PG   S G  G  G +G+ GP G  GP GP+G  G  GP GP G PG+ G  G+ G  
Sbjct: 372 GIPG---SSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTP 428

Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           GA GP G PG  GPPG  GPPG PG Q
Sbjct: 429 GAKGPTGSPGTSGPPGSAGPPGSPGPQ 455



 Score =  149 bits (377), Expect = 6e-36
 Identities = 82/160 (51%), Positives = 91/160 (56%), Gaps = 12/160 (7%)

Query: 455 LRGAPGPPGPRGFKGDMGVKG---PVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG 511
           +RG PG PG  GFKG+ G KG   P G +GP G PG  G  GP+G  G  G  GPVGERG
Sbjct: 463 IRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERG 522

Query: 512 PVGPRGFP---GLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI-- 566
             G RGFP   GL G KG+ G  GP G  GPKG  G PG  G PG PG  G  G PG+  
Sbjct: 523 APGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQG 582

Query: 567 ----AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
                G  G+PG+ G  GP G  GI+G PG  G PGP GS
Sbjct: 583 PEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGS 622



 Score =  149 bits (376), Expect = 7e-36
 Identities = 77/156 (49%), Positives = 85/156 (54%), Gaps = 9/156 (5%)

Query: 456  RGAPGPPGPRGFKGD---MGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
            RG  GPPG  GF G    +G  GP G  GP G  G  G  GP G +G PG  G VG+RGP
Sbjct: 899  RGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGP 958

Query: 513  VGPRGFPGLKGSKGSFGTGGPRGQPGP------KGDIGPPGPEGPPGSPGPSGPQGKPGI 566
             GP G PG KG  G  G  GP G PGP      +G +G PG  G  G PG  GP G PG 
Sbjct: 959  AGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGK 1018

Query: 567  AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
             G TG+ G +G  GP G PG  GP G PGP GP G+
Sbjct: 1019 VGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGN 1054



 Score =  148 bits (374), Expect = 1e-35
 Identities = 77/153 (50%), Positives = 90/153 (58%), Gaps = 6/153 (3%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE---AGPVGERGP 512
           +G  GP GP G  GD G  GP+G RGP+G PG  G  G  G  G PGE   AG  G RG 
Sbjct: 230 QGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGF 289

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGK--- 569
            G  G PGLKG +G  G  GP+G+ G  G  G  GP GP G+ GP GP+G PG  G+   
Sbjct: 290 PGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGP 349

Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
            G+PGQRGA G  G+PG  GP G+PG  G PG+
Sbjct: 350 QGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGN 382



 Score =  147 bits (372), Expect = 2e-35
 Identities = 71/150 (47%), Positives = 87/150 (58%), Gaps = 3/150 (2%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G  G PG +G  G  G  GP G  GP G PG  G  GPQG +GQPG+ G  G +G  GP+
Sbjct: 423 GTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPK 482

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGD---IGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
           G PG  G +G  G  G  G+ GP+GD   +GPPGP G  G+PG  G  G  G+ G  G+ 
Sbjct: 483 GEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQ 542

Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           G+RG +G  G  G QG PG PG PG PG++
Sbjct: 543 GERGPVGSSGPKGSQGDPGRPGEPGLPGAR 572



 Score =  146 bits (369), Expect = 5e-35
 Identities = 84/174 (48%), Positives = 95/174 (54%), Gaps = 30/174 (17%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKG------DPGSLGPLGPQGPQGQPG------EA 504
           GA GP GPRG  G+ G  GP G  G +G       PG +GPLG  G  G PG      EA
Sbjct: 330 GAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEA 389

Query: 505 GPVGERGPVGPRG------------FPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP 552
           GP G RGP GP+G             PGL G+ G+ GT G +G  G  G  GPPG  GPP
Sbjct: 390 GPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPP 449

Query: 553 GSPGP---SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           GSPGP   +GPQG  G  G  G PG +G  GPKGEP   GP G+ GP GPPG +
Sbjct: 450 GSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEP---GPHGIQGPIGPPGEE 500



 Score =  145 bits (367), Expect = 8e-35
 Identities = 76/167 (45%), Positives = 92/167 (55%), Gaps = 18/167 (10%)

Query: 457 GAPGP------PGPRGFKGDMGVKG---PVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV 507
           G PGP      PG  GF G+ G+KG   P G RGP+G  G  G  GP GP G PG  G +
Sbjct: 363 GKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAI 422

Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP------GPSGPQ 561
           G  G  G +G  G  G+ G  G+ GP G PGP+G  GP G  G PG P      G +GP+
Sbjct: 423 GTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPK 482

Query: 562 GKP---GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
           G+P   GI G  G PG+ G  GP+G+PG  GPPG  G  G PG++ F
Sbjct: 483 GEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGF 529



 Score =  145 bits (366), Expect = 1e-34
 Identities = 83/181 (45%), Positives = 92/181 (50%), Gaps = 36/181 (19%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGS---------LGPLGPQGPQGQPGEAGPV 507
           G PGP GP G KG+ G +G VG  G +G+PGS         +G  GPQGP GQPG  G  
Sbjct: 804 GPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEP 863

Query: 508 GE------------------RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPE 549
           GE                   GP GP G PGLKG +G+ G  G  G PG  G +GPPGP 
Sbjct: 864 GEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPA 923

Query: 550 GPPGSPGPSGPQGKPGIAGKTGSP------GQRGAMGPKGEPGIQGPP---GLPGPPGPP 600
           G PG  GP G  GK G  G  G P      G RG  GP G PG +G P   G PGP GPP
Sbjct: 924 GAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPP 983

Query: 601 G 601
           G
Sbjct: 984 G 984



 Score =  145 bits (366), Expect = 1e-34
 Identities = 77/158 (48%), Positives = 89/158 (56%), Gaps = 15/158 (9%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGG---RGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
            RG PGP G  G +G  G  GPVG     G +GDPGS GP+GP G  G+ G  GP G RG 
Sbjct: 1070 RGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGD 1129

Query: 513  VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572
             G  G  G +G KG  G  G +G PGP G   P G +G  G PGP GP+G PG  G +G 
Sbjct: 1130 KGDHGDRGDRGQKGHRGFTGLQGLPGPPG---PNGEQGSAGIPGPFGPRGPPGPVGPSGK 1186

Query: 573  PGQRGAMGPKGEPGI---------QGPPGLPGPPGPPG 601
             G  G +GP G PG+         +GPPG PGPPGPPG
Sbjct: 1187 EGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPG 1224



 Score =  145 bits (365), Expect = 1e-34
 Identities = 83/169 (49%), Positives = 90/169 (53%), Gaps = 24/169 (14%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G  G PG RGF G  G+ GP G +G +G  GS GP G QG  G+PGE G  G RG  G  
Sbjct: 519 GERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNP 578

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIG---PPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
           G  G +G  G  G  G  G+PGP G IG    PG  G PG  G SG  GKPG AG  G P
Sbjct: 579 GVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVP 638

Query: 574 GQRGA---------MGPKGEPGI------QGPP------GLPGPPGPPG 601
           GQRGA          GP G PG+      QGPP      GLPGPPGPPG
Sbjct: 639 GQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPG 687



 Score =  143 bits (361), Expect = 4e-34
 Identities = 76/153 (49%), Positives = 89/153 (58%), Gaps = 9/153 (5%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP------VGE 509
           +G+ GP G RG  GD GV G  G  GPKG+PG  G  GP GP G+ G+ GP      VG 
Sbjct: 455 QGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGP 514

Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGK 569
            GPVG RG PG +G  GS G  GP+G  G +G +G  GP+G  G PG  G  G PG  G 
Sbjct: 515 PGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGL 574

Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           TG+P   G  GP+G+ G  G PG  G PGPPGS
Sbjct: 575 TGNP---GVQGPEGKLGPLGAPGEDGRPGPPGS 604



 Score =  143 bits (361), Expect = 4e-34
 Identities = 76/155 (49%), Positives = 83/155 (53%), Gaps = 6/155 (3%)

Query: 455 LRGAPGP---PGPRGFKGDMGVKGPVGGRG---PKGDPGSLGPLGPQGPQGQPGEAGPVG 508
           +RG PG    PGP+G  GD G  G  G  G    +G PG  G +GP GP G PG AG  G
Sbjct: 607 IRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERG 666

Query: 509 ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAG 568
           E+GP GP GF GL G  G  G GG  G  G  GD G  GP GP G  G  G +G+PGI G
Sbjct: 667 EQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITG 726

Query: 569 KTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
             G  G  G  GP G  G  GP G PG  GPPG Q
Sbjct: 727 LPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQ 761



 Score =  143 bits (361), Expect = 4e-34
 Identities = 77/150 (51%), Positives = 81/150 (54%), Gaps = 3/150 (2%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G PG  GP G  GD G  GPVG  G  G  G  GP GP G  G PG  G VGERG  G  
Sbjct: 1014 GTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDP 1073

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ- 575
            G  GL GS+G+ GT GP G PG  G  G PG  GP G PG +G +G PG  G  G  G  
Sbjct: 1074 GPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDH 1133

Query: 576  --RGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
              RG  G KG  G  G  GLPGPPGP G Q
Sbjct: 1134 GDRGDRGQKGHRGFTGLQGLPGPPGPNGEQ 1163



 Score =  142 bits (357), Expect = 1e-33
 Identities = 73/145 (50%), Positives = 81/145 (55%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PG PG RG  G+ GV+GP G  GP G PG  G  GP G  G  G+ G +G  GP G  
Sbjct: 564 GEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSS 623

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           G PG  G  G+ G  G RG PG  G++GP GP GPPG  G  G QG PG  G  G PG  
Sbjct: 624 GDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPP 683

Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPG 601
           G  G  G+PG QG PG PG  GP G
Sbjct: 684 GPPGEGGKPGDQGVPGDPGAVGPLG 708



 Score =  141 bits (356), Expect = 2e-33
 Identities = 74/152 (48%), Positives = 84/152 (55%), Gaps = 12/152 (7%)

Query: 456 RGAPGPPGPRGFKGDMGVKGP------VGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509
           RG  GPPGP GF+G  G  GP       G +G  GDPG++GPLGP+G +G P      GE
Sbjct: 665 RGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNP------GE 718

Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGK 569
           RG  G  G PG KG  G  G  GP+G PGP G  G  GP G  G PG  G  G PG  G 
Sbjct: 719 RGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGD 778

Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  G++GA G  G  G +G PG  GPPGP G
Sbjct: 779 RGGIGEKGAEGTAGNDGARGLPGPLGPPGPAG 810



 Score =  140 bits (352), Expect = 4e-33
 Identities = 77/162 (47%), Positives = 84/162 (51%), Gaps = 15/162 (9%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP------LGPQGPQGQPGEAGPVGE 509
           RG PG  G  G  G  G KG  GG GP G  GS GP       GP G QG PGE G  G 
Sbjct: 713 RGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGT 772

Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGK 569
            GP G RG  G KG++G+ G  G RG PGP G  GP GP G  G PGP G  G PG  G 
Sbjct: 773 PGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGN 832

Query: 570 TGSPGQR---------GAMGPKGEPGIQGPPGLPGPPGPPGS 602
            GS G+          G  GP G+PG++G PG PG  G  GS
Sbjct: 833 PGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGS 874



 Score =  138 bits (348), Expect = 1e-32
 Identities = 74/158 (46%), Positives = 87/158 (55%), Gaps = 12/158 (7%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRG------PKGDPGSLGPLGPQGPQGQPGEAGPVGER 510
           GA GP GP+G +G+ G  GPVG  G        G PG+ GP G  G  G PG AGP G  
Sbjct: 393 GARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSP 452

Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGP---PGPEGPPGSPGPSGPQGKPGIA 567
           GP G  G  G++G  G  G  G +G+ GPKG+ GP    GP GPPG  G  GP+G PG  
Sbjct: 453 GPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTV 512

Query: 568 GKTGSPGQRGAMGPKGEP---GIQGPPGLPGPPGPPGS 602
           G  G  G+RGA G +G P   G+ GP G  G  GP GS
Sbjct: 513 GPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGS 550



 Score =  135 bits (339), Expect = 1e-31
 Identities = 76/182 (41%), Positives = 88/182 (48%), Gaps = 33/182 (18%)

Query: 453 TILRGAPGPPGP---------RGFKGDMGVKGPVGGRGPKGDPGSL-------------- 489
           T  +G PGPPGP         +G  GD G  GP+G RG +G+PG                
Sbjct: 674 TGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGM 733

Query: 490 -------GPLGPQGPQGQPGEAGPVGERGPVGPRGF---PGLKGSKGSFGTGGPRGQPGP 539
                  GP G  GP G PG+ GP G +G  G RG    PG KG +G  G  G  G  G 
Sbjct: 734 AGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGN 793

Query: 540 KGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGP 599
            G  G PGP GPPG  GP+G +G+PG  G  G PG RG  G +GE G  G  G  GP GP
Sbjct: 794 DGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGP 853

Query: 600 PG 601
            G
Sbjct: 854 DG 855



 Score =  134 bits (337), Expect = 2e-31
 Identities = 78/160 (48%), Positives = 82/160 (51%), Gaps = 21/160 (13%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGS---LGPLGPQGPQGQPGEAGPVGERGPV 513
            G  G PG  G  GD G  GP GG G KGDPG     GP GP GP G  G+ G VG  G  
Sbjct: 942  GLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQR 1001

Query: 514  GPRGFPGLKGSKGSFG-------TG-----GPRGQPGPKGDIGPPGPEGPPGSPGPSGPQ 561
            G RG PGL G  G+ G       TG     GP G PG  G +G PGPEGP G+       
Sbjct: 1002 GERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGN------D 1055

Query: 562  GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G PG  G  G  G RG  GP G PG QG PG PGP G PG
Sbjct: 1056 GTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPG 1095



 Score =  132 bits (332), Expect = 9e-31
 Identities = 73/154 (47%), Positives = 85/154 (55%), Gaps = 9/154 (5%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVG---GRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
           RG  G  GP+G +GD G  G  G    RG  G+PG  GP G  GP G PGE G  G  G 
Sbjct: 545 RGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGS 604

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPG---PSGPQGKPGIAGK 569
           +G RG PG  G  G  G+ G  G+PG  G+ G PG  G PG  G   PSGP G PG+AG+
Sbjct: 605 IGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGE 664

Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
               G++G  GP G  G+ GPPG PG  G PG Q
Sbjct: 665 R---GEQGPPGPTGFQGLPGPPGPPGEGGKPGDQ 695



 Score =  131 bits (330), Expect = 2e-30
 Identities = 76/172 (44%), Positives = 86/172 (50%), Gaps = 27/172 (15%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PG  G  G  G++G  GPVG  G  G+ G  GP GP G QG PG  GP GE G  G +
Sbjct: 636 GVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQ 695

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGD------------IGPPGPEGPPGSPGPSGPQGKP 564
           G PG  G+ G  G  G RG PG +G+             G  GP+GP GSPGPSG  G  
Sbjct: 696 GVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDT 755

Query: 565 GIAGKTGSPGQR---GAMGPKGE------------PGIQGPPGLPGPPGPPG 601
           G  G  G PG+R   G  GPKG+             G  G  GLPGP GPPG
Sbjct: 756 GPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPG 807



 Score =  128 bits (322), Expect = 1e-29
 Identities = 77/175 (44%), Positives = 87/175 (49%), Gaps = 30/175 (17%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLG------PQGPQGQPGEAGPVGER 510
            GA G  GP+G  G  GVKG  G  G KGD GS GP G      P GP G PG  G  G +
Sbjct: 843  GAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQ 902

Query: 511  GPVGPRGFPGLKGS------KGSFGTGGPRGQPGPKGD------------IGPPGPEGPP 552
            GP G  GFPG  G        G+ G  GP G+PG +G             +G  GP GPP
Sbjct: 903  GPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPP 962

Query: 553  GSPGPSGPQGKPGIAGKTGSP------GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G PG  G  G+ G  G  G P      GQRG +G  G+ G +G PGLPGP G PG
Sbjct: 963  GGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPG 1017



 Score =  127 bits (320), Expect = 2e-29
 Identities = 82/195 (42%), Positives = 90/195 (46%), Gaps = 51/195 (26%)

Query: 452 VTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQG---QPGEAGPVG 508
           VT +RG PGP GP G +G      P G RGPKG PG  GP G  G  G   QPG  GP G
Sbjct: 124 VTGIRGRPGPAGPPGSQG------PRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPG 177

Query: 509 ER------------------------------------GPVGPRGFPGLKGSKGSFGTGG 532
                                                 GPVGPRG  GL+G +G  G  G
Sbjct: 178 HPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTG 237

Query: 533 PRGQ---PGPKGDIGPPGPEGPPGSPGPSGPQGK---PGIAGKTGSPGQRGAMGPKGEPG 586
           P G+   PGP G IG  GPEGPPG PG  G  G+   PG  G  GSPG RG  G  G PG
Sbjct: 238 PPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPG 297

Query: 587 IQGPPGLPGPPGPPG 601
           ++G  G  G  GP G
Sbjct: 298 LKGHRGHKGLEGPKG 312



 Score = 94.4 bits (233), Expect = 3e-19
 Identities = 50/104 (48%), Positives = 59/104 (56%), Gaps = 21/104 (20%)

Query: 450  RNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509
            R  T L+G PGPPGP G +G  G+ GP G RGP G         P GP G+ G  GP+  
Sbjct: 1145 RGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPG---------PVGPSGKEGNPGPL-- 1193

Query: 510  RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPG 553
             GP+GP   PG++GS G  G  GP G+P      GPPGP GPPG
Sbjct: 1194 -GPIGP---PGVRGSVGEAGPEGPPGEP------GPPGPPGPPG 1227



 Score = 79.7 bits (195), Expect = 7e-15
 Identities = 48/110 (43%), Positives = 54/110 (49%), Gaps = 21/110 (19%)

Query: 497 PQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTG--GPRGQPG----PKGDIGPPGPEG 550
           P   PGE  PV  + P          G   +FG G  G +G+PG      G  G PGP G
Sbjct: 85  PVTPPGECCPVCSQTP---------GGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAG 135

Query: 551 PPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPP 600
           PPGS GP G +      G  G PG RG  G  GEPG+ G PG PGPPG P
Sbjct: 136 PPGSQGPRGER------GPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHP 179



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 19/36 (52%), Positives = 21/36 (58%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPL 492
            G  GPPG RG  G+ G +GP G  GP G PG  G L
Sbjct: 1194 GPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHL 1229


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
           sapiens]
          Length = 1424

 Score =  154 bits (388), Expect = 3e-37
 Identities = 82/160 (51%), Positives = 91/160 (56%), Gaps = 13/160 (8%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP-- 512
           LRG PG  G  G  G  GVKG  G +G     G  G  GP G  G PG  GP G  GP  
Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDI-------GPPGPEGPPGSPGPSGPQGKPG 565
            GP+G PGL+G++G  G  GP G+ GP+G++       GPPGP GPPG PGP GP G PG
Sbjct: 618 YGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPG 677

Query: 566 IAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
             GK G P   G  GP GEPGI G  G PGPPGP G Q F
Sbjct: 678 SLGKCGDP---GLPGPDGEPGIPG-IGFPGPPGPKGDQGF 713



 Score =  150 bits (379), Expect = 3e-36
 Identities = 80/161 (49%), Positives = 94/161 (58%), Gaps = 14/161 (8%)

Query: 457  GAPGPPGPRGFK--GDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            GAPGPPGP G    G  G KG +G  GPKG PG+ G +GP G  G PG  G  G RG  G
Sbjct: 1251 GAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPG 1310

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------PGSPGPSGPQGKPG 565
             +GFPG+KG KG+ G  G  G PGP G  GPPG  G          PGSPGP G  G+PG
Sbjct: 1311 FQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPG 1370

Query: 566  IAGKTGSPGQRGAM---GPKGEPGIQGPPGLPGPPGPPGSQ 603
            + G+ G PG  G +   GP+G+PG  G PG PGP G  G++
Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNK 1411



 Score =  146 bits (369), Expect = 5e-35
 Identities = 89/204 (43%), Positives = 98/204 (48%), Gaps = 53/204 (25%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKG---DPGSLGPLGPQGPQGQPGEAGPVGERG 511
            L G PGP G  GFKG  G+ GP G RGP G    PGS GP+G +G QG+ G  GP GE+G
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170

Query: 512  -------PVGPRG---------------FPGLKGSKGSFGTGGPRGQ------------- 536
                   P GPRG               FPGL G KG+ G  GPRG              
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 537  ----PGPKGDIGPPGPEGPPGSPGPSGP-----------QGKPGIAGKTGSPGQRGAMGP 581
                PG  G+ GPPG  G PG+PGP GP           +G  G  G  G PG  G MGP
Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP 1290

Query: 582  KGEPGIQGPPGLPGPPGPPGSQSF 605
             G  G  G PGLPGP G PG Q F
Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGF 1314



 Score =  141 bits (355), Expect = 2e-33
 Identities = 82/192 (42%), Positives = 99/192 (51%), Gaps = 43/192 (22%)

Query: 454  ILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP------- 506
            +LR  PGP G  G +G  G +G  G  G  G  G++G  GP+GP G  G  GP       
Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233

Query: 507  ----VGERGPVGPRGFP--------------GLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548
                 G RGP G RG P              G+KG KGS G  GP+G PG  GD+GPPG 
Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293

Query: 549  EGPPGSPGPSGP------QGKPGIAGKTGSP------GQRGAMGPKGEPGIQGPPG---- 592
             G PG+PG  GP      QG PG+ G+ G+P      G  G +GPKG PG++G PG    
Sbjct: 1294 LGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKI 1353

Query: 593  --LPGPPGPPGS 602
              LPG PGPPG+
Sbjct: 1354 ISLPGSPGPPGT 1365



 Score =  140 bits (352), Expect = 4e-33
 Identities = 80/173 (46%), Positives = 92/173 (53%), Gaps = 32/173 (18%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQ------PGEAGPVG 508
            L+G PGP GP G +GD+G  G  G  G +G PGS+G +G  G +G+      PG AG  G
Sbjct: 983  LKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPG 1042

Query: 509  --------------------ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548
                                  GP GP G PGL    G  G  G  GQPGP G +GP GP
Sbjct: 1043 LPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGL---PGDMGKKGEMGQPGPPGHLGPAGP 1099

Query: 549  EGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            EG PGSPG  G  GKPG  G  G  G +G +GP   PGI+GPPGLPG PG PG
Sbjct: 1100 EGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGP---PGIRGPPGLPGFPGSPG 1149



 Score =  139 bits (349), Expect = 1e-32
 Identities = 78/168 (46%), Positives = 91/168 (54%), Gaps = 24/168 (14%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQP--------------G 502
           G PGPPGP+G +G  G KG +G  G  G+PG  G  G  G +G+P              G
Sbjct: 700 GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 503 EAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS--PGPSGP 560
           E G  GE G +G  G PGL G+ G+ G  GPRG PG  G   PPG +GPPG    GP G 
Sbjct: 760 ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPG---PPGEQGPPGRCIEGPRGA 816

Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGI-----QGPPGLPGPPGPPGSQ 603
           QG PG+ G  G  G+RG  GPKG+PGI      G PG  G PG PG Q
Sbjct: 817 QGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQ 864



 Score =  136 bits (342), Expect = 6e-32
 Identities = 69/142 (48%), Positives = 83/142 (58%), Gaps = 12/142 (8%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRG------PKGDPGSLGPLGPQGPQGQPGEAGPVGER 510
            G PGP GP G  GDMG  G +G  G      P+GDPG  G  G +G +G PG  G +G  
Sbjct: 1274 GHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPP 1333

Query: 511  GPVGPRGFPGLKGSKGSF------GTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564
            GP+GP+G PG++G  G+       G+ GP G PG  G  G PGP GPPG+ GP GP+GKP
Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393

Query: 565  GIAGKTGSPGQRGAMGPKGEPG 586
            G  GK G+PG  G  G KG  G
Sbjct: 1394 GKDGKPGTPGPAGEKGNKGSKG 1415



 Score =  134 bits (337), Expect = 2e-31
 Identities = 75/151 (49%), Positives = 86/151 (56%), Gaps = 6/151 (3%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           +GAPG PG +G  G  GV G  G  G KG+ G  G +G  G +GQ G+ GP G RGP   
Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEY 346

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
                 KG +G+ G  GPRG  GP+G  GPPG  G PGS  P G +G PG  G  GS G+
Sbjct: 347 YDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRP-GLRGAPGWPGLKGSKGE 405

Query: 576 RG-----AMGPKGEPGIQGPPGLPGPPGPPG 601
           RG     AMG  G PG  G PGLPG PGPPG
Sbjct: 406 RGRPGKDAMGTPGSPGCAGSPGLPGSPGPPG 436



 Score =  134 bits (336), Expect = 3e-31
 Identities = 68/145 (46%), Positives = 81/145 (55%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PG  G  G  G  G  GP+G RG  G+PG LGP G  G  G  G  G +G  GP G  
Sbjct: 850 GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNP 909

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           G PG +GS G  G  G RG PG KG+ G  G  GP       G +G+PG+ G  G+PG++
Sbjct: 910 GTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEK 969

Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPG 601
           G  G  G PG++G  GLPGP GPPG
Sbjct: 970 GNRGVPGMPGLKGLKGLPGPAGPPG 994



 Score =  132 bits (333), Expect = 7e-31
 Identities = 75/171 (43%), Positives = 84/171 (49%), Gaps = 28/171 (16%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G PGP G  G  GDMG KG +G  GP   PG LGP GP+G  G PG  G  G+ GP G  
Sbjct: 1065 GPPGPTGDPGLPGDMGKKGEMGQPGP---PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDL 1121

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG-------------------------PEGP 551
            GF G+KG  G  G  GP G PG  G  GP G                         P GP
Sbjct: 1122 GFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGP 1181

Query: 552  PGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
             G+PG  G +G  G  G  G PG++GAMG  G  G  G  G PGPPG PG+
Sbjct: 1182 RGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGA 1232



 Score =  130 bits (328), Expect = 3e-30
 Identities = 77/172 (44%), Positives = 88/172 (51%), Gaps = 23/172 (13%)

Query: 457  GAPGPPGPRGF------KGDMGVKGPVGGRGPKGDPGSLGPLGPQGP---QGQPGEAGPV 507
            G  G PG +GF      KG+ GV G  G +G KG PG  GP GP+G     G PGE G  
Sbjct: 952  GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011

Query: 508  GERGPVGPRGFPGLKGSKGSFGTGGPRGQP---------GPKGDIG-----PPGPEGPPG 553
            G  G +G  G PG KG +G+ G  G  G+P         G KG+ G      PGP GP G
Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071

Query: 554  SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
             PG  G  GK G  G+ G PG  G  GP+G PG  G PGLPG PGP G   F
Sbjct: 1072 DPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123



 Score =  130 bits (327), Expect = 3e-30
 Identities = 73/159 (45%), Positives = 83/159 (52%), Gaps = 14/159 (8%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
           L+G+PG PG  G  G  G  G  G  G KG+ G    L P+G  G PG+ G  G+ G  G
Sbjct: 509 LKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGET--LQPEGQVGVPGDPGLRGQPGRKG 566

Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA------- 567
             G PG  G KG  G  G     G KGD GPPG  G PGSPGP+GP G PG         
Sbjct: 567 LDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626

Query: 568 ----GKTGSPGQRGAMGPKGEPGIQGP-PGLPGPPGPPG 601
               G  G+PG  G  GP+GE  +  P PG PGPPGPPG
Sbjct: 627 QGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665



 Score =  130 bits (327), Expect = 3e-30
 Identities = 80/185 (43%), Positives = 94/185 (50%), Gaps = 39/185 (21%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGR-GPKGDPGSLGPLGPQG---------------PQGQ 500
           GAPGPPG  G +G++ V  PV G  GP G PG  GP GP G               P G+
Sbjct: 634 GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGE 693

Query: 501 PGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG---------PEGP 551
           PG  G +G  GP GP+G  G  G+KGS G  G  G+PG  G  G PG         P GP
Sbjct: 694 PGIPG-IGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP 752

Query: 552 --PGSPGPSGPQGK------PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP-----G 598
             PG PG  G  G+      PG+ G  G+PG  G  GP+G+PG  GPPG  GPP     G
Sbjct: 753 GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812

Query: 599 PPGSQ 603
           P G+Q
Sbjct: 813 PRGAQ 817



 Score =  130 bits (326), Expect = 5e-30
 Identities = 74/159 (46%), Positives = 84/159 (52%), Gaps = 14/159 (8%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPG--SLGPLGPQGPQGQPGEAGPVGERGPV 513
           RGA G PG  G KG  G +G  G   PKGDPG   L   G  G  G PG  G  GE GP+
Sbjct: 814 RGAQGLPGLNGLKGQQGRRGKTG---PKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPL 870

Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
           G RG+PG  G  G  G  G  G  G  G IGPPGP G PG+PG  G  G PG+ G+ G+P
Sbjct: 871 GQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTP 930

Query: 574 GQRGAMGPKGEP---------GIQGPPGLPGPPGPPGSQ 603
           G +G  G KG P         G +G PGL G  G PG +
Sbjct: 931 GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEK 969



 Score =  129 bits (325), Expect = 6e-30
 Identities = 83/194 (42%), Positives = 90/194 (46%), Gaps = 49/194 (25%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGP------------QGQPGEA 504
           G PG PG  G KG+ G  G +G  G KG  G +GP G +GP            +G PG  
Sbjct: 303 GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP 362

Query: 505 GPVGERGPVGPR--------------------GFPGLKGSKGSFGTGG--PRGQPGPKGD 542
           GP G RGP GP                     G+PGLKGSKG  G  G    G PG  G 
Sbjct: 363 GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGC 422

Query: 543 IGPPGPEGPPGSPGP-------SGPQGKPGIAGKTGSPGQRGAMGPKGEPG--------I 587
            G PG  G PG PGP        GP G  G+ G  GSPG  G  GPKGEPG        I
Sbjct: 423 AGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYI 482

Query: 588 QGPPGLPGPPGPPG 601
            GPPGLPG PG  G
Sbjct: 483 PGPPGLPGLPGLHG 496



 Score =  125 bits (315), Expect = 9e-29
 Identities = 71/159 (44%), Positives = 82/159 (51%), Gaps = 15/159 (9%)

Query: 453 TILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
           T + G PGPPGP G  G  G  G  G  G  GDPG        GP G+PG  G +G  GP
Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGL------PGPDGEPGIPG-IGFPGP 704

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP--------PGSPGPSGPQGKP 564
            GP+G  G  G+KGS G  G  G+PG  G  G PG +G         PG+PG  G +G  
Sbjct: 705 PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNS 764

Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           G  G+ G PG  G  G  G  G+ GP G PG PGPPG Q
Sbjct: 765 GEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQ 803



 Score =  125 bits (314), Expect = 1e-28
 Identities = 79/179 (44%), Positives = 89/179 (49%), Gaps = 36/179 (20%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG----- 511
           G PGPPGPRG +G  G  GP G     G PGS  P G +G  G PG  G  GERG     
Sbjct: 357 GTPGPPGPRGARGPQGPSGPPG---VPGSPGSSRP-GLRGAPGWPGLKGSKGERGRPGKD 412

Query: 512 PVGPRGFPGLKGSKGSFGTGGPRGQPG-------PKGDIGPPGPEGPPGSPGPSGPQGKP 564
            +G  G PG  GS G  G+ GP G PG       P GD G PG  G PG PG  GP+G+P
Sbjct: 413 AMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEP 472

Query: 565 GIA--------------------GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           G+                     G  G PG++GA G KG PG  G  GLPG PG PG+Q
Sbjct: 473 GLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531



 Score =  125 bits (314), Expect = 1e-28
 Identities = 72/163 (44%), Positives = 88/163 (53%), Gaps = 15/163 (9%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGP---KGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
            +G  GP G RG+ G+ G+ GP G  G     G PG++GP GP G  G PG+ G  G  G 
Sbjct: 864  QGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGV 923

Query: 513  VGPRGFPGLKGSKGSFGTGGP---------RGQPGPKGDIGPPGPEGP---PGSPGPSGP 560
             G RG PG KG +G  G  GP         +G+PG KG  G PG +G    PG PG  G 
Sbjct: 924  KGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGL 983

Query: 561  QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            +G PG AG  G  G  G+ G  GEPG++G PG  G  G PGS+
Sbjct: 984  KGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026



 Score =  122 bits (307), Expect = 7e-28
 Identities = 75/171 (43%), Positives = 84/171 (49%), Gaps = 26/171 (15%)

Query: 457  GAPGPPGPRGFKGDMGVKGP---VGGRGPKGDPGSLGPLGPQ---GPQGQPGEAGPVGER 510
            G PG PG RG  G  GVKG     G +G +GD G+ GP       G +G+PG  G  G  
Sbjct: 907  GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP 966

Query: 511  GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------------PGSP 555
            G  G RG PG+ G KG  G  GP G PGP+GD+G  G  G                PGS 
Sbjct: 967  GEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026

Query: 556  GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQ-----GPPGLPGPPGPPG 601
            G  G  G PG AG+ G PG  G  G KGEPG       GPPG  G PG PG
Sbjct: 1027 GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPG 1077



 Score =  120 bits (300), Expect = 5e-27
 Identities = 70/161 (43%), Positives = 80/161 (49%), Gaps = 17/161 (10%)

Query: 463 GPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLK 522
           G +G KG+ G  GP G  G KG  G  G  GPQGP+G PG  G  G +G  G  G PG  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 523 GSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGA---- 578
           GS G  GT G  G  G  G  G  G +G  G PG  G  G PGI G  G  GQ+GA    
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 579 ----MGPKGEP---------GIQGPPGLPGPPGPPGSQSFY 606
               +  KG+P         G+ GPPG PGP GPPG   F+
Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFF 203



 Score =  119 bits (299), Expect = 6e-27
 Identities = 75/174 (43%), Positives = 84/174 (48%), Gaps = 24/174 (13%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEA--GPVGERGPVG 514
           G PG PGP+G  G  G  GPVG  GP G  G  G +GP+GP+G  GE   G  GERG  G
Sbjct: 174 GLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKG 233

Query: 515 PRGFPGLKGS--------------KGSFGTGGPRGQPGPKGDIGPPGP-----EGPPGSP 555
             G PG  G+              KG  G  G  G+PGP G  G PG      +G PG P
Sbjct: 234 LTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDP 293

Query: 556 GPSGPQGK---PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSFY 606
           G  G  GK   PG  G  G  G RG  G  GE GI+G  G  GPPG  G   +Y
Sbjct: 294 GLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYY 347



 Score =  119 bits (298), Expect = 8e-27
 Identities = 74/174 (42%), Positives = 84/174 (48%), Gaps = 28/174 (16%)

Query: 457 GAPGPPGPRGF---------KGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV 507
           G PGP GP+GF         KG  G+ G  G  G  G PG+ G  GP G  G PG +G  
Sbjct: 70  GLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSK 129

Query: 508 GERG------PVGPRGFPGLKGSKGSFGTGG--------PRGQPGPKGDIGPPGPEGPPG 553
           GE+G       +G  G PG  G KG  G            +G PG  G  GP G  GPPG
Sbjct: 130 GEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPG 189

Query: 554 SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGE-----PGIQGPPGLPGPPGPPGS 602
            PGP GP G PG  G  G+ G RG  G  GE      G +G  GL GPPGPPG+
Sbjct: 190 FPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGT 243



 Score =  119 bits (297), Expect = 1e-26
 Identities = 78/176 (44%), Positives = 92/176 (52%), Gaps = 28/176 (15%)

Query: 455 LRGAPGPPGP-------RGFKGDMGVKGPVGGRG------PKGDPGSLGPLGPQ--GPQG 499
           L G+PGPPGP       +G  GD G+ G +G  G      PKG+PG L    P   GP G
Sbjct: 428 LPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPG 487

Query: 500 QPGEAGPVGERGPVGPRGFPGLKGSKGSFG-TG--------GPRGQPGPKGDIG----PP 546
            PG  G  G +G  G +G  GLKGS GS G TG        G +G PG KG+ G    P 
Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPE 547

Query: 547 GPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           G  G PG PG  G  G+ G+ G  G+PG +G  GPKGE  + G  G  GPPG PGS
Sbjct: 548 GQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGS 603



 Score =  119 bits (297), Expect = 1e-26
 Identities = 67/148 (45%), Positives = 80/148 (54%), Gaps = 3/148 (2%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG---PVGERGPV 513
            GA GPPGP G  G  G +G  G  G KG  G+ G  G QG +G PG +     +G++G  
Sbjct: 898  GAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP 957

Query: 514  GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
            G +GF G  G KG+ G  G  G  G KG  GP GP GP G  G +G  G+PG+ G  GS 
Sbjct: 958  GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSM 1017

Query: 574  GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  G  G KG+ G  G PG  G PG PG
Sbjct: 1018 GNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045



 Score =  117 bits (294), Expect = 2e-26
 Identities = 71/163 (43%), Positives = 81/163 (49%), Gaps = 18/163 (11%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGPVGER 510
            G  GPPG  G  G MG  G +G  GP G+PG+ G  G       +G +G PG  G  G++
Sbjct: 880  GILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDK 939

Query: 511  GPVGP---------RGFPGLKGSKGSFGTGGPR---GQPGPKGDIGPPGPEGPPGSPGPS 558
            G  GP         +G PGLKG  G+ G  G R   G PG KG  G PGP GPPG  G  
Sbjct: 940  GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999

Query: 559  GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  G PG  G  G PG  G MG  G  G +G  G PG  G PG
Sbjct: 1000 GSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPG 1042



 Score =  117 bits (293), Expect = 3e-26
 Identities = 75/167 (44%), Positives = 87/167 (52%), Gaps = 32/167 (19%)

Query: 444 QHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE 503
           +HGEI        G PG PG  G  G+ G+ GP      +GDPG  GP    G QG PG 
Sbjct: 766 EHGEI--------GLPGLPGLPGTPGNEGLDGP------RGDPGQPGP---PGEQGPPGR 808

Query: 504 AGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPE-----GPPGSPGPS 558
                  GP G +G PGL G KG     G RG+ GPKGD G PG +     G  GSPG  
Sbjct: 809 C----IEGPRGAQGLPGLNGLKGQ---QGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIP 861

Query: 559 GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP---GPPGPPGS 602
           G QG+ G  G+ G PG  G +GP GE G+ G  G P   GPPGPPG+
Sbjct: 862 GHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGN 908



 Score = 99.8 bits (247), Expect = 7e-21
 Identities = 56/128 (43%), Positives = 71/128 (55%), Gaps = 15/128 (11%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLG------PLGPQGPQGQPGEAGPV--- 507
            GAPG PG  G +GD G +G  G +G KG+PG LG      P+GP+GP G  G+ G +   
Sbjct: 1295 GAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKII 1354

Query: 508  ---GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564
               G  GP G  G PG++G     G  GP G  GP G  G PG +G PG+PGP+G +G  
Sbjct: 1355 SLPGSPGPPGTPGEPGMQGEP---GPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNK 1411

Query: 565  GIAGKTGS 572
            G  G+  S
Sbjct: 1412 GSKGEPES 1419



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 30/65 (46%), Positives = 38/65 (58%), Gaps = 3/65 (4%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            L G+PGPPG     G+ G++G  G  GP G+ G  GP G  G  G+PG  GP GE+G  G
Sbjct: 1356 LPGSPGPPGT---PGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKG 1412

Query: 515  PRGFP 519
             +G P
Sbjct: 1413 SKGEP 1417



 Score = 32.7 bits (73), Expect = 0.99
 Identities = 18/50 (36%), Positives = 23/50 (46%), Gaps = 15/50 (30%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVG---------------GRGPKGDPGSL 489
            ++G PGPPGP G  G  G +G  G                +G KG+P SL
Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPESL 1420


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
           sapiens]
          Length = 1494

 Score =  154 bits (388), Expect = 3e-37
 Identities = 82/160 (51%), Positives = 91/160 (56%), Gaps = 13/160 (8%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP-- 512
           LRG PG  G  G  G  GVKG  G +G     G  G  GP G  G PG  GP G  GP  
Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDI-------GPPGPEGPPGSPGPSGPQGKPG 565
            GP+G PGL+G++G  G  GP G+ GP+G++       GPPGP GPPG PGP GP G PG
Sbjct: 618 YGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPG 677

Query: 566 IAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
             GK G P   G  GP GEPGI G  G PGPPGP G Q F
Sbjct: 678 SLGKCGDP---GLPGPDGEPGIPG-IGFPGPPGPKGDQGF 713



 Score =  150 bits (379), Expect = 3e-36
 Identities = 80/161 (49%), Positives = 94/161 (58%), Gaps = 14/161 (8%)

Query: 457  GAPGPPGPRGFK--GDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            GAPGPPGP G    G  G KG +G  GPKG PG+ G +GP G  G PG  G  G RG  G
Sbjct: 1251 GAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPG 1310

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------PGSPGPSGPQGKPG 565
             +GFPG+KG KG+ G  G  G PGP G  GPPG  G          PGSPGP G  G+PG
Sbjct: 1311 FQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPG 1370

Query: 566  IAGKTGSPGQRGAM---GPKGEPGIQGPPGLPGPPGPPGSQ 603
            + G+ G PG  G +   GP+G+PG  G PG PGP G  G++
Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNK 1411



 Score =  149 bits (375), Expect = 9e-36
 Identities = 78/160 (48%), Positives = 94/160 (58%), Gaps = 15/160 (9%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRG------PKGDPGSLGPLGPQGPQGQPGEAGPVGER 510
            G PGP GP G  GDMG  G +G  G      P+GDPG  G  G +G +G PG  G +G  
Sbjct: 1274 GHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPP 1333

Query: 511  GPVGPRGFPGLKGSKGSF------GTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564
            GP+GP+G PG++G  G+       G+ GP G PG  G  G PGP GPPG+ GP GP+GKP
Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393

Query: 565  GIAGKTGSP---GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  GK G+P   G++G  G KGEPG  G  GLPG  G  G
Sbjct: 1394 GKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433



 Score =  146 bits (369), Expect = 5e-35
 Identities = 89/204 (43%), Positives = 98/204 (48%), Gaps = 53/204 (25%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKG---DPGSLGPLGPQGPQGQPGEAGPVGERG 511
            L G PGP G  GFKG  G+ GP G RGP G    PGS GP+G +G QG+ G  GP GE+G
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170

Query: 512  -------PVGPRG---------------FPGLKGSKGSFGTGGPRGQ------------- 536
                   P GPRG               FPGL G KG+ G  GPRG              
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 537  ----PGPKGDIGPPGPEGPPGSPGPSGP-----------QGKPGIAGKTGSPGQRGAMGP 581
                PG  G+ GPPG  G PG+PGP GP           +G  G  G  G PG  G MGP
Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP 1290

Query: 582  KGEPGIQGPPGLPGPPGPPGSQSF 605
             G  G  G PGLPGP G PG Q F
Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGF 1314



 Score =  141 bits (355), Expect = 2e-33
 Identities = 82/192 (42%), Positives = 99/192 (51%), Gaps = 43/192 (22%)

Query: 454  ILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP------- 506
            +LR  PGP G  G +G  G +G  G  G  G  G++G  GP+GP G  G  GP       
Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233

Query: 507  ----VGERGPVGPRGFP--------------GLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548
                 G RGP G RG P              G+KG KGS G  GP+G PG  GD+GPPG 
Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293

Query: 549  EGPPGSPGPSGP------QGKPGIAGKTGSP------GQRGAMGPKGEPGIQGPPG---- 592
             G PG+PG  GP      QG PG+ G+ G+P      G  G +GPKG PG++G PG    
Sbjct: 1294 LGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKI 1353

Query: 593  --LPGPPGPPGS 602
              LPG PGPPG+
Sbjct: 1354 ISLPGSPGPPGT 1365



 Score =  140 bits (352), Expect = 4e-33
 Identities = 80/173 (46%), Positives = 92/173 (53%), Gaps = 32/173 (18%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQ------PGEAGPVG 508
            L+G PGP GP G +GD+G  G  G  G +G PGS+G +G  G +G+      PG AG  G
Sbjct: 983  LKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPG 1042

Query: 509  --------------------ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548
                                  GP GP G PGL    G  G  G  GQPGP G +GP GP
Sbjct: 1043 LPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGL---PGDMGKKGEMGQPGPPGHLGPAGP 1099

Query: 549  EGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            EG PGSPG  G  GKPG  G  G  G +G +GP   PGI+GPPGLPG PG PG
Sbjct: 1100 EGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGP---PGIRGPPGLPGFPGSPG 1149



 Score =  139 bits (349), Expect = 1e-32
 Identities = 78/168 (46%), Positives = 91/168 (54%), Gaps = 24/168 (14%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQP--------------G 502
           G PGPPGP+G +G  G KG +G  G  G+PG  G  G  G +G+P              G
Sbjct: 700 GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 503 EAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS--PGPSGP 560
           E G  GE G +G  G PGL G+ G+ G  GPRG PG  G   PPG +GPPG    GP G 
Sbjct: 760 ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPG---PPGEQGPPGRCIEGPRGA 816

Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGI-----QGPPGLPGPPGPPGSQ 603
           QG PG+ G  G  G+RG  GPKG+PGI      G PG  G PG PG Q
Sbjct: 817 QGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQ 864



 Score =  134 bits (337), Expect = 2e-31
 Identities = 75/151 (49%), Positives = 86/151 (56%), Gaps = 6/151 (3%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           +GAPG PG +G  G  GV G  G  G KG+ G  G +G  G +GQ G+ GP G RGP   
Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEY 346

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
                 KG +G+ G  GPRG  GP+G  GPPG  G PGS  P G +G PG  G  GS G+
Sbjct: 347 YDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRP-GLRGAPGWPGLKGSKGE 405

Query: 576 RG-----AMGPKGEPGIQGPPGLPGPPGPPG 601
           RG     AMG  G PG  G PGLPG PGPPG
Sbjct: 406 RGRPGKDAMGTPGSPGCAGSPGLPGSPGPPG 436



 Score =  134 bits (336), Expect = 3e-31
 Identities = 68/145 (46%), Positives = 81/145 (55%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PG  G  G  G  G  GP+G RG  G+PG LGP G  G  G  G  G +G  GP G  
Sbjct: 850 GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNP 909

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           G PG +GS G  G  G RG PG KG+ G  G  GP       G +G+PG+ G  G+PG++
Sbjct: 910 GTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEK 969

Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPG 601
           G  G  G PG++G  GLPGP GPPG
Sbjct: 970 GNRGVPGMPGLKGLKGLPGPAGPPG 994



 Score =  132 bits (333), Expect = 7e-31
 Identities = 75/171 (43%), Positives = 84/171 (49%), Gaps = 28/171 (16%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G PGP G  G  GDMG KG +G  GP   PG LGP GP+G  G PG  G  G+ GP G  
Sbjct: 1065 GPPGPTGDPGLPGDMGKKGEMGQPGP---PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDL 1121

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG-------------------------PEGP 551
            GF G+KG  G  G  GP G PG  G  GP G                         P GP
Sbjct: 1122 GFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGP 1181

Query: 552  PGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
             G+PG  G +G  G  G  G PG++GAMG  G  G  G  G PGPPG PG+
Sbjct: 1182 RGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGA 1232



 Score =  130 bits (328), Expect = 3e-30
 Identities = 77/172 (44%), Positives = 88/172 (51%), Gaps = 23/172 (13%)

Query: 457  GAPGPPGPRGF------KGDMGVKGPVGGRGPKGDPGSLGPLGPQGP---QGQPGEAGPV 507
            G  G PG +GF      KG+ GV G  G +G KG PG  GP GP+G     G PGE G  
Sbjct: 952  GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011

Query: 508  GERGPVGPRGFPGLKGSKGSFGTGGPRGQP---------GPKGDIG-----PPGPEGPPG 553
            G  G +G  G PG KG +G+ G  G  G+P         G KG+ G      PGP GP G
Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071

Query: 554  SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
             PG  G  GK G  G+ G PG  G  GP+G PG  G PGLPG PGP G   F
Sbjct: 1072 DPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123



 Score =  130 bits (327), Expect = 3e-30
 Identities = 73/159 (45%), Positives = 83/159 (52%), Gaps = 14/159 (8%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
           L+G+PG PG  G  G  G  G  G  G KG+ G    L P+G  G PG+ G  G+ G  G
Sbjct: 509 LKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGET--LQPEGQVGVPGDPGLRGQPGRKG 566

Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA------- 567
             G PG  G KG  G  G     G KGD GPPG  G PGSPGP+GP G PG         
Sbjct: 567 LDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626

Query: 568 ----GKTGSPGQRGAMGPKGEPGIQGP-PGLPGPPGPPG 601
               G  G+PG  G  GP+GE  +  P PG PGPPGPPG
Sbjct: 627 QGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665



 Score =  130 bits (327), Expect = 3e-30
 Identities = 80/185 (43%), Positives = 94/185 (50%), Gaps = 39/185 (21%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGR-GPKGDPGSLGPLGPQG---------------PQGQ 500
           GAPGPPG  G +G++ V  PV G  GP G PG  GP GP G               P G+
Sbjct: 634 GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGE 693

Query: 501 PGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG---------PEGP 551
           PG  G +G  GP GP+G  G  G+KGS G  G  G+PG  G  G PG         P GP
Sbjct: 694 PGIPG-IGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP 752

Query: 552 --PGSPGPSGPQGK------PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP-----G 598
             PG PG  G  G+      PG+ G  G+PG  G  GP+G+PG  GPPG  GPP     G
Sbjct: 753 GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812

Query: 599 PPGSQ 603
           P G+Q
Sbjct: 813 PRGAQ 817



 Score =  130 bits (326), Expect = 5e-30
 Identities = 74/159 (46%), Positives = 84/159 (52%), Gaps = 14/159 (8%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPG--SLGPLGPQGPQGQPGEAGPVGERGPV 513
           RGA G PG  G KG  G +G  G   PKGDPG   L   G  G  G PG  G  GE GP+
Sbjct: 814 RGAQGLPGLNGLKGQQGRRGKTG---PKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPL 870

Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
           G RG+PG  G  G  G  G  G  G  G IGPPGP G PG+PG  G  G PG+ G+ G+P
Sbjct: 871 GQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTP 930

Query: 574 GQRGAMGPKGEP---------GIQGPPGLPGPPGPPGSQ 603
           G +G  G KG P         G +G PGL G  G PG +
Sbjct: 931 GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEK 969



 Score =  129 bits (325), Expect = 6e-30
 Identities = 83/194 (42%), Positives = 90/194 (46%), Gaps = 49/194 (25%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGP------------QGQPGEA 504
           G PG PG  G KG+ G  G +G  G KG  G +GP G +GP            +G PG  
Sbjct: 303 GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP 362

Query: 505 GPVGERGPVGPR--------------------GFPGLKGSKGSFGTGG--PRGQPGPKGD 542
           GP G RGP GP                     G+PGLKGSKG  G  G    G PG  G 
Sbjct: 363 GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGC 422

Query: 543 IGPPGPEGPPGSPGP-------SGPQGKPGIAGKTGSPGQRGAMGPKGEPG--------I 587
            G PG  G PG PGP        GP G  G+ G  GSPG  G  GPKGEPG        I
Sbjct: 423 AGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYI 482

Query: 588 QGPPGLPGPPGPPG 601
            GPPGLPG PG  G
Sbjct: 483 PGPPGLPGLPGLHG 496



 Score =  125 bits (315), Expect = 9e-29
 Identities = 71/159 (44%), Positives = 82/159 (51%), Gaps = 15/159 (9%)

Query: 453 TILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
           T + G PGPPGP G  G  G  G  G  G  GDPG        GP G+PG  G +G  GP
Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGL------PGPDGEPGIPG-IGFPGP 704

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP--------PGSPGPSGPQGKP 564
            GP+G  G  G+KGS G  G  G+PG  G  G PG +G         PG+PG  G +G  
Sbjct: 705 PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNS 764

Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           G  G+ G PG  G  G  G  G+ GP G PG PGPPG Q
Sbjct: 765 GEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQ 803



 Score =  125 bits (314), Expect = 1e-28
 Identities = 79/179 (44%), Positives = 89/179 (49%), Gaps = 36/179 (20%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG----- 511
           G PGPPGPRG +G  G  GP G     G PGS  P G +G  G PG  G  GERG     
Sbjct: 357 GTPGPPGPRGARGPQGPSGPPG---VPGSPGSSRP-GLRGAPGWPGLKGSKGERGRPGKD 412

Query: 512 PVGPRGFPGLKGSKGSFGTGGPRGQPG-------PKGDIGPPGPEGPPGSPGPSGPQGKP 564
            +G  G PG  GS G  G+ GP G PG       P GD G PG  G PG PG  GP+G+P
Sbjct: 413 AMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEP 472

Query: 565 GIA--------------------GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           G+                     G  G PG++GA G KG PG  G  GLPG PG PG+Q
Sbjct: 473 GLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531



 Score =  125 bits (314), Expect = 1e-28
 Identities = 72/163 (44%), Positives = 88/163 (53%), Gaps = 15/163 (9%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGP---KGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
            +G  GP G RG+ G+ G+ GP G  G     G PG++GP GP G  G PG+ G  G  G 
Sbjct: 864  QGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGV 923

Query: 513  VGPRGFPGLKGSKGSFGTGGP---------RGQPGPKGDIGPPGPEGP---PGSPGPSGP 560
             G RG PG KG +G  G  GP         +G+PG KG  G PG +G    PG PG  G 
Sbjct: 924  KGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGL 983

Query: 561  QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            +G PG AG  G  G  G+ G  GEPG++G PG  G  G PGS+
Sbjct: 984  KGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026



 Score =  122 bits (307), Expect = 7e-28
 Identities = 75/171 (43%), Positives = 84/171 (49%), Gaps = 26/171 (15%)

Query: 457  GAPGPPGPRGFKGDMGVKGP---VGGRGPKGDPGSLGPLGPQ---GPQGQPGEAGPVGER 510
            G PG PG RG  G  GVKG     G +G +GD G+ GP       G +G+PG  G  G  
Sbjct: 907  GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP 966

Query: 511  GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------------PGSP 555
            G  G RG PG+ G KG  G  GP G PGP+GD+G  G  G                PGS 
Sbjct: 967  GEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026

Query: 556  GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQ-----GPPGLPGPPGPPG 601
            G  G  G PG AG+ G PG  G  G KGEPG       GPPG  G PG PG
Sbjct: 1027 GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPG 1077



 Score =  120 bits (300), Expect = 5e-27
 Identities = 70/161 (43%), Positives = 80/161 (49%), Gaps = 17/161 (10%)

Query: 463 GPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLK 522
           G +G KG+ G  GP G  G KG  G  G  GPQGP+G PG  G  G +G  G  G PG  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 523 GSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGA---- 578
           GS G  GT G  G  G  G  G  G +G  G PG  G  G PGI G  G  GQ+GA    
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 579 ----MGPKGEP---------GIQGPPGLPGPPGPPGSQSFY 606
               +  KG+P         G+ GPPG PGP GPPG   F+
Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFF 203



 Score =  119 bits (299), Expect = 6e-27
 Identities = 75/174 (43%), Positives = 84/174 (48%), Gaps = 24/174 (13%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEA--GPVGERGPVG 514
           G PG PGP+G  G  G  GPVG  GP G  G  G +GP+GP+G  GE   G  GERG  G
Sbjct: 174 GLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKG 233

Query: 515 PRGFPGLKGS--------------KGSFGTGGPRGQPGPKGDIGPPGP-----EGPPGSP 555
             G PG  G+              KG  G  G  G+PGP G  G PG      +G PG P
Sbjct: 234 LTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDP 293

Query: 556 GPSGPQGK---PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSFY 606
           G  G  GK   PG  G  G  G RG  G  GE GI+G  G  GPPG  G   +Y
Sbjct: 294 GLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYY 347



 Score =  119 bits (298), Expect = 8e-27
 Identities = 74/174 (42%), Positives = 84/174 (48%), Gaps = 28/174 (16%)

Query: 457 GAPGPPGPRGF---------KGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV 507
           G PGP GP+GF         KG  G+ G  G  G  G PG+ G  GP G  G PG +G  
Sbjct: 70  GLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSK 129

Query: 508 GERG------PVGPRGFPGLKGSKGSFGTGG--------PRGQPGPKGDIGPPGPEGPPG 553
           GE+G       +G  G PG  G KG  G            +G PG  G  GP G  GPPG
Sbjct: 130 GEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPG 189

Query: 554 SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGE-----PGIQGPPGLPGPPGPPGS 602
            PGP GP G PG  G  G+ G RG  G  GE      G +G  GL GPPGPPG+
Sbjct: 190 FPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGT 243



 Score =  119 bits (297), Expect = 1e-26
 Identities = 78/176 (44%), Positives = 92/176 (52%), Gaps = 28/176 (15%)

Query: 455 LRGAPGPPGP-------RGFKGDMGVKGPVGGRG------PKGDPGSLGPLGPQ--GPQG 499
           L G+PGPPGP       +G  GD G+ G +G  G      PKG+PG L    P   GP G
Sbjct: 428 LPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPG 487

Query: 500 QPGEAGPVGERGPVGPRGFPGLKGSKGSFG-TG--------GPRGQPGPKGDIG----PP 546
            PG  G  G +G  G +G  GLKGS GS G TG        G +G PG KG+ G    P 
Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPE 547

Query: 547 GPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           G  G PG PG  G  G+ G+ G  G+PG +G  GPKGE  + G  G  GPPG PGS
Sbjct: 548 GQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGS 603



 Score =  119 bits (297), Expect = 1e-26
 Identities = 67/148 (45%), Positives = 80/148 (54%), Gaps = 3/148 (2%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG---PVGERGPV 513
            GA GPPGP G  G  G +G  G  G KG  G+ G  G QG +G PG +     +G++G  
Sbjct: 898  GAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP 957

Query: 514  GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
            G +GF G  G KG+ G  G  G  G KG  GP GP GP G  G +G  G+PG+ G  GS 
Sbjct: 958  GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSM 1017

Query: 574  GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  G  G KG+ G  G PG  G PG PG
Sbjct: 1018 GNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045



 Score =  117 bits (294), Expect = 2e-26
 Identities = 71/163 (43%), Positives = 81/163 (49%), Gaps = 18/163 (11%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGPVGER 510
            G  GPPG  G  G MG  G +G  GP G+PG+ G  G       +G +G PG  G  G++
Sbjct: 880  GILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDK 939

Query: 511  GPVGP---------RGFPGLKGSKGSFGTGGPR---GQPGPKGDIGPPGPEGPPGSPGPS 558
            G  GP         +G PGLKG  G+ G  G R   G PG KG  G PGP GPPG  G  
Sbjct: 940  GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999

Query: 559  GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  G PG  G  G PG  G MG  G  G +G  G PG  G PG
Sbjct: 1000 GSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPG 1042



 Score =  117 bits (293), Expect = 3e-26
 Identities = 75/167 (44%), Positives = 87/167 (52%), Gaps = 32/167 (19%)

Query: 444 QHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE 503
           +HGEI        G PG PG  G  G+ G+ GP      +GDPG  GP    G QG PG 
Sbjct: 766 EHGEI--------GLPGLPGLPGTPGNEGLDGP------RGDPGQPGP---PGEQGPPGR 808

Query: 504 AGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPE-----GPPGSPGPS 558
                  GP G +G PGL G KG     G RG+ GPKGD G PG +     G  GSPG  
Sbjct: 809 C----IEGPRGAQGLPGLNGLKGQ---QGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIP 861

Query: 559 GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP---GPPGPPGS 602
           G QG+ G  G+ G PG  G +GP GE G+ G  G P   GPPGPPG+
Sbjct: 862 GHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGN 908



 Score =  104 bits (259), Expect = 3e-22
 Identities = 63/153 (41%), Positives = 74/153 (48%), Gaps = 36/153 (23%)

Query: 457  GAPGPPGPRG------------------FKGDMGVKGPVGGRGP---KGDPGSLGPL--- 492
            G PG PGPRG                  F G +G  GP+G +GP   +GDPG+L  +   
Sbjct: 1298 GTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLP 1357

Query: 493  GPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP 552
            G  GP G PGE G  GE GP GP          G+ G  GPRG+PG     G PG  GP 
Sbjct: 1358 GSPGPPGTPGEPGMQGEPGPPGP---------PGNLGPCGPRGKPGKD---GKPGTPGPA 1405

Query: 553  GSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEP 585
            G  G  G +G+PG AG  G PG +G  G  G P
Sbjct: 1406 GEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 41/92 (44%), Positives = 48/92 (52%), Gaps = 9/92 (9%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            L G+PGPPG  G  G  G  GP         PG  G LGP GP+G+PG+ G  G  GP G
Sbjct: 1356 LPGSPGPPGTPGEPGMQGEPGP---------PGPPGNLGPCGPRGKPGKDGKPGTPGPAG 1406

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPP 546
             +G  G KG  G  G+ G  G  G +GD G P
Sbjct: 1407 EKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 31/93 (33%), Positives = 39/93 (41%), Gaps = 12/93 (12%)

Query: 455  LRGAPGPPGPRGFKGDMGVKG------------PVGGRGPKGDPGSLGPLGPQGPQGQPG 502
            ++G PGPPGP G  G  G +G            P G +G KG  G  GP G  G  G  G
Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKG 1430

Query: 503  EAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRG 535
            + G  G       RGF   + S+ +     P G
Sbjct: 1431 KRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEG 1463


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
           sapiens]
          Length = 1637

 Score =  154 bits (388), Expect = 3e-37
 Identities = 82/160 (51%), Positives = 91/160 (56%), Gaps = 13/160 (8%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP-- 512
           LRG PG  G  G  G  GVKG  G +G     G  G  GP G  G PG  GP G  GP  
Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDI-------GPPGPEGPPGSPGPSGPQGKPG 565
            GP+G PGL+G++G  G  GP G+ GP+G++       GPPGP GPPG PGP GP G PG
Sbjct: 618 YGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPG 677

Query: 566 IAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
             GK G P   G  GP GEPGI G  G PGPPGP G Q F
Sbjct: 678 SLGKCGDP---GLPGPDGEPGIPG-IGFPGPPGPKGDQGF 713



 Score =  150 bits (379), Expect = 3e-36
 Identities = 80/161 (49%), Positives = 94/161 (58%), Gaps = 14/161 (8%)

Query: 457  GAPGPPGPRGFK--GDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            GAPGPPGP G    G  G KG +G  GPKG PG+ G +GP G  G PG  G  G RG  G
Sbjct: 1251 GAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPG 1310

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------PGSPGPSGPQGKPG 565
             +GFPG+KG KG+ G  G  G PGP G  GPPG  G          PGSPGP G  G+PG
Sbjct: 1311 FQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPG 1370

Query: 566  IAGKTGSPGQRGAM---GPKGEPGIQGPPGLPGPPGPPGSQ 603
            + G+ G PG  G +   GP+G+PG  G PG PGP G  G++
Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNK 1411



 Score =  149 bits (375), Expect = 9e-36
 Identities = 78/160 (48%), Positives = 94/160 (58%), Gaps = 15/160 (9%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRG------PKGDPGSLGPLGPQGPQGQPGEAGPVGER 510
            G PGP GP G  GDMG  G +G  G      P+GDPG  G  G +G +G PG  G +G  
Sbjct: 1274 GHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPP 1333

Query: 511  GPVGPRGFPGLKGSKGSF------GTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564
            GP+GP+G PG++G  G+       G+ GP G PG  G  G PGP GPPG+ GP GP+GKP
Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393

Query: 565  GIAGKTGSP---GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  GK G+P   G++G  G KGEPG  G  GLPG  G  G
Sbjct: 1394 GKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433



 Score =  146 bits (369), Expect = 5e-35
 Identities = 89/204 (43%), Positives = 98/204 (48%), Gaps = 53/204 (25%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKG---DPGSLGPLGPQGPQGQPGEAGPVGERG 511
            L G PGP G  GFKG  G+ GP G RGP G    PGS GP+G +G QG+ G  GP GE+G
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170

Query: 512  -------PVGPRG---------------FPGLKGSKGSFGTGGPRGQ------------- 536
                   P GPRG               FPGL G KG+ G  GPRG              
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 537  ----PGPKGDIGPPGPEGPPGSPGPSGP-----------QGKPGIAGKTGSPGQRGAMGP 581
                PG  G+ GPPG  G PG+PGP GP           +G  G  G  G PG  G MGP
Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP 1290

Query: 582  KGEPGIQGPPGLPGPPGPPGSQSF 605
             G  G  G PGLPGP G PG Q F
Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGF 1314



 Score =  141 bits (355), Expect = 2e-33
 Identities = 82/192 (42%), Positives = 99/192 (51%), Gaps = 43/192 (22%)

Query: 454  ILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP------- 506
            +LR  PGP G  G +G  G +G  G  G  G  G++G  GP+GP G  G  GP       
Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233

Query: 507  ----VGERGPVGPRGFP--------------GLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548
                 G RGP G RG P              G+KG KGS G  GP+G PG  GD+GPPG 
Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293

Query: 549  EGPPGSPGPSGP------QGKPGIAGKTGSP------GQRGAMGPKGEPGIQGPPG---- 592
             G PG+PG  GP      QG PG+ G+ G+P      G  G +GPKG PG++G PG    
Sbjct: 1294 LGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKI 1353

Query: 593  --LPGPPGPPGS 602
              LPG PGPPG+
Sbjct: 1354 ISLPGSPGPPGT 1365



 Score =  140 bits (352), Expect = 4e-33
 Identities = 80/173 (46%), Positives = 92/173 (53%), Gaps = 32/173 (18%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQ------PGEAGPVG 508
            L+G PGP GP G +GD+G  G  G  G +G PGS+G +G  G +G+      PG AG  G
Sbjct: 983  LKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPG 1042

Query: 509  --------------------ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548
                                  GP GP G PGL    G  G  G  GQPGP G +GP GP
Sbjct: 1043 LPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGL---PGDMGKKGEMGQPGPPGHLGPAGP 1099

Query: 549  EGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            EG PGSPG  G  GKPG  G  G  G +G +GP   PGI+GPPGLPG PG PG
Sbjct: 1100 EGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGP---PGIRGPPGLPGFPGSPG 1149



 Score =  139 bits (349), Expect = 1e-32
 Identities = 78/168 (46%), Positives = 91/168 (54%), Gaps = 24/168 (14%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQP--------------G 502
           G PGPPGP+G +G  G KG +G  G  G+PG  G  G  G +G+P              G
Sbjct: 700 GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 503 EAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS--PGPSGP 560
           E G  GE G +G  G PGL G+ G+ G  GPRG PG  G   PPG +GPPG    GP G 
Sbjct: 760 ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPG---PPGEQGPPGRCIEGPRGA 816

Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGI-----QGPPGLPGPPGPPGSQ 603
           QG PG+ G  G  G+RG  GPKG+PGI      G PG  G PG PG Q
Sbjct: 817 QGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQ 864



 Score =  134 bits (337), Expect = 2e-31
 Identities = 75/151 (49%), Positives = 86/151 (56%), Gaps = 6/151 (3%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           +GAPG PG +G  G  GV G  G  G KG+ G  G +G  G +GQ G+ GP G RGP   
Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEY 346

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
                 KG +G+ G  GPRG  GP+G  GPPG  G PGS  P G +G PG  G  GS G+
Sbjct: 347 YDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRP-GLRGAPGWPGLKGSKGE 405

Query: 576 RG-----AMGPKGEPGIQGPPGLPGPPGPPG 601
           RG     AMG  G PG  G PGLPG PGPPG
Sbjct: 406 RGRPGKDAMGTPGSPGCAGSPGLPGSPGPPG 436



 Score =  134 bits (336), Expect = 3e-31
 Identities = 68/145 (46%), Positives = 81/145 (55%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PG  G  G  G  G  GP+G RG  G+PG LGP G  G  G  G  G +G  GP G  
Sbjct: 850 GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNP 909

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           G PG +GS G  G  G RG PG KG+ G  G  GP       G +G+PG+ G  G+PG++
Sbjct: 910 GTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEK 969

Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPG 601
           G  G  G PG++G  GLPGP GPPG
Sbjct: 970 GNRGVPGMPGLKGLKGLPGPAGPPG 994



 Score =  132 bits (333), Expect = 7e-31
 Identities = 75/171 (43%), Positives = 84/171 (49%), Gaps = 28/171 (16%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G PGP G  G  GDMG KG +G  GP   PG LGP GP+G  G PG  G  G+ GP G  
Sbjct: 1065 GPPGPTGDPGLPGDMGKKGEMGQPGP---PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDL 1121

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG-------------------------PEGP 551
            GF G+KG  G  G  GP G PG  G  GP G                         P GP
Sbjct: 1122 GFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGP 1181

Query: 552  PGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
             G+PG  G +G  G  G  G PG++GAMG  G  G  G  G PGPPG PG+
Sbjct: 1182 RGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGA 1232



 Score =  130 bits (328), Expect = 3e-30
 Identities = 77/172 (44%), Positives = 88/172 (51%), Gaps = 23/172 (13%)

Query: 457  GAPGPPGPRGF------KGDMGVKGPVGGRGPKGDPGSLGPLGPQGP---QGQPGEAGPV 507
            G  G PG +GF      KG+ GV G  G +G KG PG  GP GP+G     G PGE G  
Sbjct: 952  GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011

Query: 508  GERGPVGPRGFPGLKGSKGSFGTGGPRGQP---------GPKGDIG-----PPGPEGPPG 553
            G  G +G  G PG KG +G+ G  G  G+P         G KG+ G      PGP GP G
Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071

Query: 554  SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
             PG  G  GK G  G+ G PG  G  GP+G PG  G PGLPG PGP G   F
Sbjct: 1072 DPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123



 Score =  130 bits (327), Expect = 3e-30
 Identities = 73/159 (45%), Positives = 83/159 (52%), Gaps = 14/159 (8%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
           L+G+PG PG  G  G  G  G  G  G KG+ G    L P+G  G PG+ G  G+ G  G
Sbjct: 509 LKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGET--LQPEGQVGVPGDPGLRGQPGRKG 566

Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA------- 567
             G PG  G KG  G  G     G KGD GPPG  G PGSPGP+GP G PG         
Sbjct: 567 LDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626

Query: 568 ----GKTGSPGQRGAMGPKGEPGIQGP-PGLPGPPGPPG 601
               G  G+PG  G  GP+GE  +  P PG PGPPGPPG
Sbjct: 627 QGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665



 Score =  130 bits (327), Expect = 3e-30
 Identities = 80/185 (43%), Positives = 94/185 (50%), Gaps = 39/185 (21%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGR-GPKGDPGSLGPLGPQG---------------PQGQ 500
           GAPGPPG  G +G++ V  PV G  GP G PG  GP GP G               P G+
Sbjct: 634 GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGE 693

Query: 501 PGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG---------PEGP 551
           PG  G +G  GP GP+G  G  G+KGS G  G  G+PG  G  G PG         P GP
Sbjct: 694 PGIPG-IGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP 752

Query: 552 --PGSPGPSGPQGK------PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP-----G 598
             PG PG  G  G+      PG+ G  G+PG  G  GP+G+PG  GPPG  GPP     G
Sbjct: 753 GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812

Query: 599 PPGSQ 603
           P G+Q
Sbjct: 813 PRGAQ 817



 Score =  130 bits (326), Expect = 5e-30
 Identities = 74/159 (46%), Positives = 84/159 (52%), Gaps = 14/159 (8%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPG--SLGPLGPQGPQGQPGEAGPVGERGPV 513
           RGA G PG  G KG  G +G  G   PKGDPG   L   G  G  G PG  G  GE GP+
Sbjct: 814 RGAQGLPGLNGLKGQQGRRGKTG---PKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPL 870

Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
           G RG+PG  G  G  G  G  G  G  G IGPPGP G PG+PG  G  G PG+ G+ G+P
Sbjct: 871 GQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTP 930

Query: 574 GQRGAMGPKGEP---------GIQGPPGLPGPPGPPGSQ 603
           G +G  G KG P         G +G PGL G  G PG +
Sbjct: 931 GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEK 969



 Score =  129 bits (325), Expect = 6e-30
 Identities = 83/194 (42%), Positives = 90/194 (46%), Gaps = 49/194 (25%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGP------------QGQPGEA 504
           G PG PG  G KG+ G  G +G  G KG  G +GP G +GP            +G PG  
Sbjct: 303 GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP 362

Query: 505 GPVGERGPVGPR--------------------GFPGLKGSKGSFGTGG--PRGQPGPKGD 542
           GP G RGP GP                     G+PGLKGSKG  G  G    G PG  G 
Sbjct: 363 GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGC 422

Query: 543 IGPPGPEGPPGSPGP-------SGPQGKPGIAGKTGSPGQRGAMGPKGEPG--------I 587
            G PG  G PG PGP        GP G  G+ G  GSPG  G  GPKGEPG        I
Sbjct: 423 AGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYI 482

Query: 588 QGPPGLPGPPGPPG 601
            GPPGLPG PG  G
Sbjct: 483 PGPPGLPGLPGLHG 496



 Score =  125 bits (315), Expect = 9e-29
 Identities = 71/159 (44%), Positives = 82/159 (51%), Gaps = 15/159 (9%)

Query: 453 TILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
           T + G PGPPGP G  G  G  G  G  G  GDPG        GP G+PG  G +G  GP
Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGL------PGPDGEPGIPG-IGFPGP 704

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP--------PGSPGPSGPQGKP 564
            GP+G  G  G+KGS G  G  G+PG  G  G PG +G         PG+PG  G +G  
Sbjct: 705 PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNS 764

Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           G  G+ G PG  G  G  G  G+ GP G PG PGPPG Q
Sbjct: 765 GEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQ 803



 Score =  125 bits (314), Expect = 1e-28
 Identities = 79/179 (44%), Positives = 89/179 (49%), Gaps = 36/179 (20%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG----- 511
           G PGPPGPRG +G  G  GP G     G PGS  P G +G  G PG  G  GERG     
Sbjct: 357 GTPGPPGPRGARGPQGPSGPPG---VPGSPGSSRP-GLRGAPGWPGLKGSKGERGRPGKD 412

Query: 512 PVGPRGFPGLKGSKGSFGTGGPRGQPG-------PKGDIGPPGPEGPPGSPGPSGPQGKP 564
            +G  G PG  GS G  G+ GP G PG       P GD G PG  G PG PG  GP+G+P
Sbjct: 413 AMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEP 472

Query: 565 GIA--------------------GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           G+                     G  G PG++GA G KG PG  G  GLPG PG PG+Q
Sbjct: 473 GLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531



 Score =  125 bits (314), Expect = 1e-28
 Identities = 72/163 (44%), Positives = 88/163 (53%), Gaps = 15/163 (9%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGP---KGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
            +G  GP G RG+ G+ G+ GP G  G     G PG++GP GP G  G PG+ G  G  G 
Sbjct: 864  QGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGV 923

Query: 513  VGPRGFPGLKGSKGSFGTGGP---------RGQPGPKGDIGPPGPEGP---PGSPGPSGP 560
             G RG PG KG +G  G  GP         +G+PG KG  G PG +G    PG PG  G 
Sbjct: 924  KGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGL 983

Query: 561  QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            +G PG AG  G  G  G+ G  GEPG++G PG  G  G PGS+
Sbjct: 984  KGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026



 Score =  122 bits (307), Expect = 7e-28
 Identities = 75/171 (43%), Positives = 84/171 (49%), Gaps = 26/171 (15%)

Query: 457  GAPGPPGPRGFKGDMGVKGP---VGGRGPKGDPGSLGPLGPQ---GPQGQPGEAGPVGER 510
            G PG PG RG  G  GVKG     G +G +GD G+ GP       G +G+PG  G  G  
Sbjct: 907  GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP 966

Query: 511  GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------------PGSP 555
            G  G RG PG+ G KG  G  GP G PGP+GD+G  G  G                PGS 
Sbjct: 967  GEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026

Query: 556  GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQ-----GPPGLPGPPGPPG 601
            G  G  G PG AG+ G PG  G  G KGEPG       GPPG  G PG PG
Sbjct: 1027 GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPG 1077



 Score =  120 bits (300), Expect = 5e-27
 Identities = 70/161 (43%), Positives = 80/161 (49%), Gaps = 17/161 (10%)

Query: 463 GPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLK 522
           G +G KG+ G  GP G  G KG  G  G  GPQGP+G PG  G  G +G  G  G PG  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 523 GSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGA---- 578
           GS G  GT G  G  G  G  G  G +G  G PG  G  G PGI G  G  GQ+GA    
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 579 ----MGPKGEP---------GIQGPPGLPGPPGPPGSQSFY 606
               +  KG+P         G+ GPPG PGP GPPG   F+
Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFF 203



 Score =  119 bits (299), Expect = 6e-27
 Identities = 75/174 (43%), Positives = 84/174 (48%), Gaps = 24/174 (13%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEA--GPVGERGPVG 514
           G PG PGP+G  G  G  GPVG  GP G  G  G +GP+GP+G  GE   G  GERG  G
Sbjct: 174 GLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKG 233

Query: 515 PRGFPGLKGS--------------KGSFGTGGPRGQPGPKGDIGPPGP-----EGPPGSP 555
             G PG  G+              KG  G  G  G+PGP G  G PG      +G PG P
Sbjct: 234 LTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDP 293

Query: 556 GPSGPQGK---PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSFY 606
           G  G  GK   PG  G  G  G RG  G  GE GI+G  G  GPPG  G   +Y
Sbjct: 294 GLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYY 347



 Score =  119 bits (298), Expect = 8e-27
 Identities = 74/174 (42%), Positives = 84/174 (48%), Gaps = 28/174 (16%)

Query: 457 GAPGPPGPRGF---------KGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV 507
           G PGP GP+GF         KG  G+ G  G  G  G PG+ G  GP G  G PG +G  
Sbjct: 70  GLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSK 129

Query: 508 GERG------PVGPRGFPGLKGSKGSFGTGG--------PRGQPGPKGDIGPPGPEGPPG 553
           GE+G       +G  G PG  G KG  G            +G PG  G  GP G  GPPG
Sbjct: 130 GEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPG 189

Query: 554 SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGE-----PGIQGPPGLPGPPGPPGS 602
            PGP GP G PG  G  G+ G RG  G  GE      G +G  GL GPPGPPG+
Sbjct: 190 FPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGT 243



 Score =  119 bits (297), Expect = 1e-26
 Identities = 78/176 (44%), Positives = 92/176 (52%), Gaps = 28/176 (15%)

Query: 455 LRGAPGPPGP-------RGFKGDMGVKGPVGGRG------PKGDPGSLGPLGPQ--GPQG 499
           L G+PGPPGP       +G  GD G+ G +G  G      PKG+PG L    P   GP G
Sbjct: 428 LPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPG 487

Query: 500 QPGEAGPVGERGPVGPRGFPGLKGSKGSFG-TG--------GPRGQPGPKGDIG----PP 546
            PG  G  G +G  G +G  GLKGS GS G TG        G +G PG KG+ G    P 
Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPE 547

Query: 547 GPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           G  G PG PG  G  G+ G+ G  G+PG +G  GPKGE  + G  G  GPPG PGS
Sbjct: 548 GQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGS 603



 Score =  119 bits (297), Expect = 1e-26
 Identities = 67/148 (45%), Positives = 80/148 (54%), Gaps = 3/148 (2%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG---PVGERGPV 513
            GA GPPGP G  G  G +G  G  G KG  G+ G  G QG +G PG +     +G++G  
Sbjct: 898  GAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP 957

Query: 514  GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
            G +GF G  G KG+ G  G  G  G KG  GP GP GP G  G +G  G+PG+ G  GS 
Sbjct: 958  GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSM 1017

Query: 574  GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  G  G KG+ G  G PG  G PG PG
Sbjct: 1018 GNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045



 Score =  117 bits (294), Expect = 2e-26
 Identities = 71/163 (43%), Positives = 81/163 (49%), Gaps = 18/163 (11%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGPVGER 510
            G  GPPG  G  G MG  G +G  GP G+PG+ G  G       +G +G PG  G  G++
Sbjct: 880  GILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDK 939

Query: 511  GPVGP---------RGFPGLKGSKGSFGTGGPR---GQPGPKGDIGPPGPEGPPGSPGPS 558
            G  GP         +G PGLKG  G+ G  G R   G PG KG  G PGP GPPG  G  
Sbjct: 940  GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999

Query: 559  GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  G PG  G  G PG  G MG  G  G +G  G PG  G PG
Sbjct: 1000 GSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPG 1042



 Score =  117 bits (293), Expect = 3e-26
 Identities = 75/167 (44%), Positives = 87/167 (52%), Gaps = 32/167 (19%)

Query: 444 QHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE 503
           +HGEI        G PG PG  G  G+ G+ GP      +GDPG  GP    G QG PG 
Sbjct: 766 EHGEI--------GLPGLPGLPGTPGNEGLDGP------RGDPGQPGP---PGEQGPPGR 808

Query: 504 AGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPE-----GPPGSPGPS 558
                  GP G +G PGL G KG     G RG+ GPKGD G PG +     G  GSPG  
Sbjct: 809 C----IEGPRGAQGLPGLNGLKGQ---QGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIP 861

Query: 559 GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP---GPPGPPGS 602
           G QG+ G  G+ G PG  G +GP GE G+ G  G P   GPPGPPG+
Sbjct: 862 GHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGN 908



 Score =  104 bits (259), Expect = 3e-22
 Identities = 63/153 (41%), Positives = 74/153 (48%), Gaps = 36/153 (23%)

Query: 457  GAPGPPGPRG------------------FKGDMGVKGPVGGRGP---KGDPGSLGPL--- 492
            G PG PGPRG                  F G +G  GP+G +GP   +GDPG+L  +   
Sbjct: 1298 GTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLP 1357

Query: 493  GPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP 552
            G  GP G PGE G  GE GP GP          G+ G  GPRG+PG     G PG  GP 
Sbjct: 1358 GSPGPPGTPGEPGMQGEPGPPGP---------PGNLGPCGPRGKPGKD---GKPGTPGPA 1405

Query: 553  GSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEP 585
            G  G  G +G+PG AG  G PG +G  G  G P
Sbjct: 1406 GEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 41/92 (44%), Positives = 48/92 (52%), Gaps = 9/92 (9%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            L G+PGPPG  G  G  G  GP         PG  G LGP GP+G+PG+ G  G  GP G
Sbjct: 1356 LPGSPGPPGTPGEPGMQGEPGP---------PGPPGNLGPCGPRGKPGKDGKPGTPGPAG 1406

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPP 546
             +G  G KG  G  G+ G  G  G +GD G P
Sbjct: 1407 EKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 31/93 (33%), Positives = 39/93 (41%), Gaps = 12/93 (12%)

Query: 455  LRGAPGPPGPRGFKGDMGVKG------------PVGGRGPKGDPGSLGPLGPQGPQGQPG 502
            ++G PGPPGP G  G  G +G            P G +G KG  G  GP G  G  G  G
Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKG 1430

Query: 503  EAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRG 535
            + G  G       RGF   + S+ +     P G
Sbjct: 1431 KRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEG 1463


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
           sapiens]
          Length = 1670

 Score =  154 bits (388), Expect = 3e-37
 Identities = 82/160 (51%), Positives = 91/160 (56%), Gaps = 13/160 (8%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP-- 512
           LRG PG  G  G  G  GVKG  G +G     G  G  GP G  G PG  GP G  GP  
Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDI-------GPPGPEGPPGSPGPSGPQGKPG 565
            GP+G PGL+G++G  G  GP G+ GP+G++       GPPGP GPPG PGP GP G PG
Sbjct: 618 YGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPG 677

Query: 566 IAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
             GK G P   G  GP GEPGI G  G PGPPGP G Q F
Sbjct: 678 SLGKCGDP---GLPGPDGEPGIPG-IGFPGPPGPKGDQGF 713



 Score =  150 bits (379), Expect = 3e-36
 Identities = 80/161 (49%), Positives = 94/161 (58%), Gaps = 14/161 (8%)

Query: 457  GAPGPPGPRGFK--GDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            GAPGPPGP G    G  G KG +G  GPKG PG+ G +GP G  G PG  G  G RG  G
Sbjct: 1251 GAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPG 1310

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------PGSPGPSGPQGKPG 565
             +GFPG+KG KG+ G  G  G PGP G  GPPG  G          PGSPGP G  G+PG
Sbjct: 1311 FQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPG 1370

Query: 566  IAGKTGSPGQRGAM---GPKGEPGIQGPPGLPGPPGPPGSQ 603
            + G+ G PG  G +   GP+G+PG  G PG PGP G  G++
Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNK 1411



 Score =  149 bits (375), Expect = 9e-36
 Identities = 78/160 (48%), Positives = 94/160 (58%), Gaps = 15/160 (9%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRG------PKGDPGSLGPLGPQGPQGQPGEAGPVGER 510
            G PGP GP G  GDMG  G +G  G      P+GDPG  G  G +G +G PG  G +G  
Sbjct: 1274 GHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPP 1333

Query: 511  GPVGPRGFPGLKGSKGSF------GTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564
            GP+GP+G PG++G  G+       G+ GP G PG  G  G PGP GPPG+ GP GP+GKP
Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393

Query: 565  GIAGKTGSP---GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  GK G+P   G++G  G KGEPG  G  GLPG  G  G
Sbjct: 1394 GKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433



 Score =  146 bits (369), Expect = 5e-35
 Identities = 89/204 (43%), Positives = 98/204 (48%), Gaps = 53/204 (25%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKG---DPGSLGPLGPQGPQGQPGEAGPVGERG 511
            L G PGP G  GFKG  G+ GP G RGP G    PGS GP+G +G QG+ G  GP GE+G
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170

Query: 512  -------PVGPRG---------------FPGLKGSKGSFGTGGPRGQ------------- 536
                   P GPRG               FPGL G KG+ G  GPRG              
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 537  ----PGPKGDIGPPGPEGPPGSPGPSGP-----------QGKPGIAGKTGSPGQRGAMGP 581
                PG  G+ GPPG  G PG+PGP GP           +G  G  G  G PG  G MGP
Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP 1290

Query: 582  KGEPGIQGPPGLPGPPGPPGSQSF 605
             G  G  G PGLPGP G PG Q F
Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGF 1314



 Score =  141 bits (355), Expect = 2e-33
 Identities = 82/192 (42%), Positives = 99/192 (51%), Gaps = 43/192 (22%)

Query: 454  ILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP------- 506
            +LR  PGP G  G +G  G +G  G  G  G  G++G  GP+GP G  G  GP       
Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233

Query: 507  ----VGERGPVGPRGFP--------------GLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548
                 G RGP G RG P              G+KG KGS G  GP+G PG  GD+GPPG 
Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293

Query: 549  EGPPGSPGPSGP------QGKPGIAGKTGSP------GQRGAMGPKGEPGIQGPPG---- 592
             G PG+PG  GP      QG PG+ G+ G+P      G  G +GPKG PG++G PG    
Sbjct: 1294 LGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKI 1353

Query: 593  --LPGPPGPPGS 602
              LPG PGPPG+
Sbjct: 1354 ISLPGSPGPPGT 1365



 Score =  140 bits (352), Expect = 4e-33
 Identities = 80/173 (46%), Positives = 92/173 (53%), Gaps = 32/173 (18%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQ------PGEAGPVG 508
            L+G PGP GP G +GD+G  G  G  G +G PGS+G +G  G +G+      PG AG  G
Sbjct: 983  LKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPG 1042

Query: 509  --------------------ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548
                                  GP GP G PGL    G  G  G  GQPGP G +GP GP
Sbjct: 1043 LPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGL---PGDMGKKGEMGQPGPPGHLGPAGP 1099

Query: 549  EGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            EG PGSPG  G  GKPG  G  G  G +G +GP   PGI+GPPGLPG PG PG
Sbjct: 1100 EGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGP---PGIRGPPGLPGFPGSPG 1149



 Score =  139 bits (349), Expect = 1e-32
 Identities = 78/168 (46%), Positives = 91/168 (54%), Gaps = 24/168 (14%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQP--------------G 502
           G PGPPGP+G +G  G KG +G  G  G+PG  G  G  G +G+P              G
Sbjct: 700 GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 503 EAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS--PGPSGP 560
           E G  GE G +G  G PGL G+ G+ G  GPRG PG  G   PPG +GPPG    GP G 
Sbjct: 760 ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPG---PPGEQGPPGRCIEGPRGA 816

Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGI-----QGPPGLPGPPGPPGSQ 603
           QG PG+ G  G  G+RG  GPKG+PGI      G PG  G PG PG Q
Sbjct: 817 QGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQ 864



 Score =  134 bits (337), Expect = 2e-31
 Identities = 75/151 (49%), Positives = 86/151 (56%), Gaps = 6/151 (3%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           +GAPG PG +G  G  GV G  G  G KG+ G  G +G  G +GQ G+ GP G RGP   
Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEY 346

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
                 KG +G+ G  GPRG  GP+G  GPPG  G PGS  P G +G PG  G  GS G+
Sbjct: 347 YDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRP-GLRGAPGWPGLKGSKGE 405

Query: 576 RG-----AMGPKGEPGIQGPPGLPGPPGPPG 601
           RG     AMG  G PG  G PGLPG PGPPG
Sbjct: 406 RGRPGKDAMGTPGSPGCAGSPGLPGSPGPPG 436



 Score =  134 bits (336), Expect = 3e-31
 Identities = 68/145 (46%), Positives = 81/145 (55%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PG  G  G  G  G  GP+G RG  G+PG LGP G  G  G  G  G +G  GP G  
Sbjct: 850 GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNP 909

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           G PG +GS G  G  G RG PG KG+ G  G  GP       G +G+PG+ G  G+PG++
Sbjct: 910 GTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEK 969

Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPG 601
           G  G  G PG++G  GLPGP GPPG
Sbjct: 970 GNRGVPGMPGLKGLKGLPGPAGPPG 994



 Score =  132 bits (333), Expect = 7e-31
 Identities = 75/171 (43%), Positives = 84/171 (49%), Gaps = 28/171 (16%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            G PGP G  G  GDMG KG +G  GP   PG LGP GP+G  G PG  G  G+ GP G  
Sbjct: 1065 GPPGPTGDPGLPGDMGKKGEMGQPGP---PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDL 1121

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG-------------------------PEGP 551
            GF G+KG  G  G  GP G PG  G  GP G                         P GP
Sbjct: 1122 GFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGP 1181

Query: 552  PGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
             G+PG  G +G  G  G  G PG++GAMG  G  G  G  G PGPPG PG+
Sbjct: 1182 RGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGA 1232



 Score =  130 bits (328), Expect = 3e-30
 Identities = 77/172 (44%), Positives = 88/172 (51%), Gaps = 23/172 (13%)

Query: 457  GAPGPPGPRGF------KGDMGVKGPVGGRGPKGDPGSLGPLGPQGP---QGQPGEAGPV 507
            G  G PG +GF      KG+ GV G  G +G KG PG  GP GP+G     G PGE G  
Sbjct: 952  GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011

Query: 508  GERGPVGPRGFPGLKGSKGSFGTGGPRGQP---------GPKGDIG-----PPGPEGPPG 553
            G  G +G  G PG KG +G+ G  G  G+P         G KG+ G      PGP GP G
Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071

Query: 554  SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
             PG  G  GK G  G+ G PG  G  GP+G PG  G PGLPG PGP G   F
Sbjct: 1072 DPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123



 Score =  130 bits (327), Expect = 3e-30
 Identities = 73/159 (45%), Positives = 83/159 (52%), Gaps = 14/159 (8%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
           L+G+PG PG  G  G  G  G  G  G KG+ G    L P+G  G PG+ G  G+ G  G
Sbjct: 509 LKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGET--LQPEGQVGVPGDPGLRGQPGRKG 566

Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA------- 567
             G PG  G KG  G  G     G KGD GPPG  G PGSPGP+GP G PG         
Sbjct: 567 LDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626

Query: 568 ----GKTGSPGQRGAMGPKGEPGIQGP-PGLPGPPGPPG 601
               G  G+PG  G  GP+GE  +  P PG PGPPGPPG
Sbjct: 627 QGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665



 Score =  130 bits (327), Expect = 3e-30
 Identities = 80/185 (43%), Positives = 94/185 (50%), Gaps = 39/185 (21%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGR-GPKGDPGSLGPLGPQG---------------PQGQ 500
           GAPGPPG  G +G++ V  PV G  GP G PG  GP GP G               P G+
Sbjct: 634 GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGE 693

Query: 501 PGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG---------PEGP 551
           PG  G +G  GP GP+G  G  G+KGS G  G  G+PG  G  G PG         P GP
Sbjct: 694 PGIPG-IGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP 752

Query: 552 --PGSPGPSGPQGK------PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP-----G 598
             PG PG  G  G+      PG+ G  G+PG  G  GP+G+PG  GPPG  GPP     G
Sbjct: 753 GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812

Query: 599 PPGSQ 603
           P G+Q
Sbjct: 813 PRGAQ 817



 Score =  130 bits (326), Expect = 5e-30
 Identities = 74/159 (46%), Positives = 84/159 (52%), Gaps = 14/159 (8%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPG--SLGPLGPQGPQGQPGEAGPVGERGPV 513
           RGA G PG  G KG  G +G  G   PKGDPG   L   G  G  G PG  G  GE GP+
Sbjct: 814 RGAQGLPGLNGLKGQQGRRGKTG---PKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPL 870

Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
           G RG+PG  G  G  G  G  G  G  G IGPPGP G PG+PG  G  G PG+ G+ G+P
Sbjct: 871 GQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTP 930

Query: 574 GQRGAMGPKGEP---------GIQGPPGLPGPPGPPGSQ 603
           G +G  G KG P         G +G PGL G  G PG +
Sbjct: 931 GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEK 969



 Score =  129 bits (325), Expect = 6e-30
 Identities = 83/194 (42%), Positives = 90/194 (46%), Gaps = 49/194 (25%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGP------------QGQPGEA 504
           G PG PG  G KG+ G  G +G  G KG  G +GP G +GP            +G PG  
Sbjct: 303 GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP 362

Query: 505 GPVGERGPVGPR--------------------GFPGLKGSKGSFGTGG--PRGQPGPKGD 542
           GP G RGP GP                     G+PGLKGSKG  G  G    G PG  G 
Sbjct: 363 GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGC 422

Query: 543 IGPPGPEGPPGSPGP-------SGPQGKPGIAGKTGSPGQRGAMGPKGEPG--------I 587
            G PG  G PG PGP        GP G  G+ G  GSPG  G  GPKGEPG        I
Sbjct: 423 AGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYI 482

Query: 588 QGPPGLPGPPGPPG 601
            GPPGLPG PG  G
Sbjct: 483 PGPPGLPGLPGLHG 496



 Score =  125 bits (315), Expect = 9e-29
 Identities = 71/159 (44%), Positives = 82/159 (51%), Gaps = 15/159 (9%)

Query: 453 TILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
           T + G PGPPGP G  G  G  G  G  G  GDPG        GP G+PG  G +G  GP
Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGL------PGPDGEPGIPG-IGFPGP 704

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP--------PGSPGPSGPQGKP 564
            GP+G  G  G+KGS G  G  G+PG  G  G PG +G         PG+PG  G +G  
Sbjct: 705 PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNS 764

Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           G  G+ G PG  G  G  G  G+ GP G PG PGPPG Q
Sbjct: 765 GEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQ 803



 Score =  125 bits (314), Expect = 1e-28
 Identities = 79/179 (44%), Positives = 89/179 (49%), Gaps = 36/179 (20%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG----- 511
           G PGPPGPRG +G  G  GP G     G PGS  P G +G  G PG  G  GERG     
Sbjct: 357 GTPGPPGPRGARGPQGPSGPPG---VPGSPGSSRP-GLRGAPGWPGLKGSKGERGRPGKD 412

Query: 512 PVGPRGFPGLKGSKGSFGTGGPRGQPG-------PKGDIGPPGPEGPPGSPGPSGPQGKP 564
            +G  G PG  GS G  G+ GP G PG       P GD G PG  G PG PG  GP+G+P
Sbjct: 413 AMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEP 472

Query: 565 GIA--------------------GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           G+                     G  G PG++GA G KG PG  G  GLPG PG PG+Q
Sbjct: 473 GLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531



 Score =  125 bits (314), Expect = 1e-28
 Identities = 72/163 (44%), Positives = 88/163 (53%), Gaps = 15/163 (9%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGP---KGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
            +G  GP G RG+ G+ G+ GP G  G     G PG++GP GP G  G PG+ G  G  G 
Sbjct: 864  QGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGV 923

Query: 513  VGPRGFPGLKGSKGSFGTGGP---------RGQPGPKGDIGPPGPEGP---PGSPGPSGP 560
             G RG PG KG +G  G  GP         +G+PG KG  G PG +G    PG PG  G 
Sbjct: 924  KGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGL 983

Query: 561  QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            +G PG AG  G  G  G+ G  GEPG++G PG  G  G PGS+
Sbjct: 984  KGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026



 Score =  122 bits (307), Expect = 7e-28
 Identities = 75/171 (43%), Positives = 84/171 (49%), Gaps = 26/171 (15%)

Query: 457  GAPGPPGPRGFKGDMGVKGP---VGGRGPKGDPGSLGPLGPQ---GPQGQPGEAGPVGER 510
            G PG PG RG  G  GVKG     G +G +GD G+ GP       G +G+PG  G  G  
Sbjct: 907  GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP 966

Query: 511  GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------------PGSP 555
            G  G RG PG+ G KG  G  GP G PGP+GD+G  G  G                PGS 
Sbjct: 967  GEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026

Query: 556  GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQ-----GPPGLPGPPGPPG 601
            G  G  G PG AG+ G PG  G  G KGEPG       GPPG  G PG PG
Sbjct: 1027 GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPG 1077



 Score =  120 bits (300), Expect = 5e-27
 Identities = 70/161 (43%), Positives = 80/161 (49%), Gaps = 17/161 (10%)

Query: 463 GPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLK 522
           G +G KG+ G  GP G  G KG  G  G  GPQGP+G PG  G  G +G  G  G PG  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 523 GSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGA---- 578
           GS G  GT G  G  G  G  G  G +G  G PG  G  G PGI G  G  GQ+GA    
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 579 ----MGPKGEP---------GIQGPPGLPGPPGPPGSQSFY 606
               +  KG+P         G+ GPPG PGP GPPG   F+
Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFF 203



 Score =  119 bits (299), Expect = 6e-27
 Identities = 75/174 (43%), Positives = 84/174 (48%), Gaps = 24/174 (13%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEA--GPVGERGPVG 514
           G PG PGP+G  G  G  GPVG  GP G  G  G +GP+GP+G  GE   G  GERG  G
Sbjct: 174 GLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKG 233

Query: 515 PRGFPGLKGS--------------KGSFGTGGPRGQPGPKGDIGPPGP-----EGPPGSP 555
             G PG  G+              KG  G  G  G+PGP G  G PG      +G PG P
Sbjct: 234 LTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDP 293

Query: 556 GPSGPQGK---PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSFY 606
           G  G  GK   PG  G  G  G RG  G  GE GI+G  G  GPPG  G   +Y
Sbjct: 294 GLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYY 347



 Score =  119 bits (298), Expect = 8e-27
 Identities = 74/174 (42%), Positives = 84/174 (48%), Gaps = 28/174 (16%)

Query: 457 GAPGPPGPRGF---------KGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV 507
           G PGP GP+GF         KG  G+ G  G  G  G PG+ G  GP G  G PG +G  
Sbjct: 70  GLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSK 129

Query: 508 GERG------PVGPRGFPGLKGSKGSFGTGG--------PRGQPGPKGDIGPPGPEGPPG 553
           GE+G       +G  G PG  G KG  G            +G PG  G  GP G  GPPG
Sbjct: 130 GEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPG 189

Query: 554 SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGE-----PGIQGPPGLPGPPGPPGS 602
            PGP GP G PG  G  G+ G RG  G  GE      G +G  GL GPPGPPG+
Sbjct: 190 FPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGT 243



 Score =  119 bits (297), Expect = 1e-26
 Identities = 78/176 (44%), Positives = 92/176 (52%), Gaps = 28/176 (15%)

Query: 455 LRGAPGPPGP-------RGFKGDMGVKGPVGGRG------PKGDPGSLGPLGPQ--GPQG 499
           L G+PGPPGP       +G  GD G+ G +G  G      PKG+PG L    P   GP G
Sbjct: 428 LPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPG 487

Query: 500 QPGEAGPVGERGPVGPRGFPGLKGSKGSFG-TG--------GPRGQPGPKGDIG----PP 546
            PG  G  G +G  G +G  GLKGS GS G TG        G +G PG KG+ G    P 
Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPE 547

Query: 547 GPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           G  G PG PG  G  G+ G+ G  G+PG +G  GPKGE  + G  G  GPPG PGS
Sbjct: 548 GQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGS 603



 Score =  119 bits (297), Expect = 1e-26
 Identities = 67/148 (45%), Positives = 80/148 (54%), Gaps = 3/148 (2%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG---PVGERGPV 513
            GA GPPGP G  G  G +G  G  G KG  G+ G  G QG +G PG +     +G++G  
Sbjct: 898  GAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP 957

Query: 514  GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
            G +GF G  G KG+ G  G  G  G KG  GP GP GP G  G +G  G+PG+ G  GS 
Sbjct: 958  GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSM 1017

Query: 574  GQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  G  G KG+ G  G PG  G PG PG
Sbjct: 1018 GNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045



 Score =  117 bits (294), Expect = 2e-26
 Identities = 71/163 (43%), Positives = 81/163 (49%), Gaps = 18/163 (11%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGPVGER 510
            G  GPPG  G  G MG  G +G  GP G+PG+ G  G       +G +G PG  G  G++
Sbjct: 880  GILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDK 939

Query: 511  GPVGP---------RGFPGLKGSKGSFGTGGPR---GQPGPKGDIGPPGPEGPPGSPGPS 558
            G  GP         +G PGLKG  G+ G  G R   G PG KG  G PGP GPPG  G  
Sbjct: 940  GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999

Query: 559  GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  G PG  G  G PG  G MG  G  G +G  G PG  G PG
Sbjct: 1000 GSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPG 1042



 Score =  117 bits (293), Expect = 3e-26
 Identities = 75/167 (44%), Positives = 87/167 (52%), Gaps = 32/167 (19%)

Query: 444 QHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE 503
           +HGEI        G PG PG  G  G+ G+ GP      +GDPG  GP    G QG PG 
Sbjct: 766 EHGEI--------GLPGLPGLPGTPGNEGLDGP------RGDPGQPGP---PGEQGPPGR 808

Query: 504 AGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPE-----GPPGSPGPS 558
                  GP G +G PGL G KG     G RG+ GPKGD G PG +     G  GSPG  
Sbjct: 809 C----IEGPRGAQGLPGLNGLKGQ---QGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIP 861

Query: 559 GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP---GPPGPPGS 602
           G QG+ G  G+ G PG  G +GP GE G+ G  G P   GPPGPPG+
Sbjct: 862 GHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGN 908



 Score =  104 bits (259), Expect = 3e-22
 Identities = 63/153 (41%), Positives = 74/153 (48%), Gaps = 36/153 (23%)

Query: 457  GAPGPPGPRG------------------FKGDMGVKGPVGGRGP---KGDPGSLGPL--- 492
            G PG PGPRG                  F G +G  GP+G +GP   +GDPG+L  +   
Sbjct: 1298 GTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLP 1357

Query: 493  GPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP 552
            G  GP G PGE G  GE GP GP          G+ G  GPRG+PG     G PG  GP 
Sbjct: 1358 GSPGPPGTPGEPGMQGEPGPPGP---------PGNLGPCGPRGKPGKD---GKPGTPGPA 1405

Query: 553  GSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEP 585
            G  G  G +G+PG AG  G PG +G  G  G P
Sbjct: 1406 GEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 41/92 (44%), Positives = 48/92 (52%), Gaps = 9/92 (9%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            L G+PGPPG  G  G  G  GP         PG  G LGP GP+G+PG+ G  G  GP G
Sbjct: 1356 LPGSPGPPGTPGEPGMQGEPGP---------PGPPGNLGPCGPRGKPGKDGKPGTPGPAG 1406

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPP 546
             +G  G KG  G  G+ G  G  G +GD G P
Sbjct: 1407 EKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 31/93 (33%), Positives = 39/93 (41%), Gaps = 12/93 (12%)

Query: 455  LRGAPGPPGPRGFKGDMGVKG------------PVGGRGPKGDPGSLGPLGPQGPQGQPG 502
            ++G PGPPGP G  G  G +G            P G +G KG  G  GP G  G  G  G
Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKG 1430

Query: 503  EAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRG 535
            + G  G       RGF   + S+ +     P G
Sbjct: 1431 KRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEG 1463


>gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens]
          Length = 540

 Score =  154 bits (388), Expect = 3e-37
 Identities = 81/169 (47%), Positives = 96/169 (56%), Gaps = 23/169 (13%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVG------GRGPKGDPGSLGPLG---PQGPQGQPGEAGP 506
           +GAPG  GPRG +G  G  GP G       RGP GD G  GP G   P GP+G+PG+ G 
Sbjct: 165 KGAPGDFGPRGDQGQDGAAGPPGPPGPPGARGPPGDTGKDGPRGAQGPAGPKGEPGQDGE 224

Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566
           +G +GP GP+G PG+ G KG  GT    G PGPKG+ G  GP G  G  G  GP+G+PG 
Sbjct: 225 MGPKGPPGPKGEPGVPGKKGDDGTPSQPGPPGPKGEPGSMGPRGENGVDGAPGPKGEPGH 284

Query: 567 AGKTGSPGQRGAMGPKGEPG--------------IQGPPGLPGPPGPPG 601
            G  G+ G RGA G KGE G              ++GPPG  GPPGPPG
Sbjct: 285 RGTDGAAGPRGAPGLKGEQGDTVVIDYDGRILDALKGPPGPQGPPGPPG 333



 Score =  151 bits (382), Expect = 1e-36
 Identities = 79/167 (47%), Positives = 94/167 (56%), Gaps = 21/167 (12%)

Query: 456 RGAPGPPGPRG---FKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
           RG PGPPG  G   + G +G+ G  G  GPKG+ G+ G  GP+G QGQ G AGP G  GP
Sbjct: 132 RGDPGPPGQSGRDGYPGPLGLDGKPGLPGPKGEKGAPGDFGPRGDQGQDGAAGPPGPPGP 191

Query: 513 VGPRGFPG---LKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP---------------PGS 554
            G RG PG     G +G+ G  GP+G+PG  G++GP GP GP               P  
Sbjct: 192 PGARGPPGDTGKDGPRGAQGPAGPKGEPGQDGEMGPKGPPGPKGEPGVPGKKGDDGTPSQ 251

Query: 555 PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           PGP GP+G+PG  G  G  G  GA GPKGEPG +G  G  GP G PG
Sbjct: 252 PGPPGPKGEPGSMGPRGENGVDGAPGPKGEPGHRGTDGAAGPRGAPG 298



 Score =  132 bits (332), Expect = 9e-31
 Identities = 81/201 (40%), Positives = 92/201 (45%), Gaps = 54/201 (26%)

Query: 457 GAPGPPGPRGF------KGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGER 510
           G  GPPGP+G       KGD G     G  GPKG+PGS+GP G  G  G PG  G  G R
Sbjct: 226 GPKGPPGPKGEPGVPGKKGDDGTPSQPGPPGPKGEPGSMGPRGENGVDGAPGPKGEPGHR 285

Query: 511 GP---VGPRGFPGLKGSKGSF--------------GTGGPRGQPGPKG------------ 541
           G     GPRG PGLKG +G                G  GP+G PGP G            
Sbjct: 286 GTDGAAGPRGAPGLKGEQGDTVVIDYDGRILDALKGPPGPQGPPGPPGIPGAKGELGLPG 345

Query: 542 ------DIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQ------- 588
                 + GP G +G PG PGP+G +G+ G  G +G PG  G  G KGE           
Sbjct: 346 APGIDGEKGPKGQKGDPGEPGPAGLKGEAGEMGLSGLPGADGLKGEKGESASDSLQESLA 405

Query: 589 ------GPPGLPGPPGPPGSQ 603
                 GPPG PGPPGP G Q
Sbjct: 406 QLIVEPGPPGPPGPPGPMGLQ 426



 Score =  127 bits (320), Expect = 2e-29
 Identities = 69/138 (50%), Positives = 78/138 (56%), Gaps = 18/138 (13%)

Query: 482 PKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGL---KGSKGSFGTGGPRGQPG 538
           P G PG  G  G +G  G PG++G  G  GP+G  G PGL   KG KG+ G  GPRG  G
Sbjct: 119 PPGPPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDGKPGLPGPKGEKGAPGDFGPRGDQG 178

Query: 539 PKGDIGPPGPEGPPGSPGP------SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPG 592
             G  GPPGP GPPG+ GP       GP+G  G AG  G PGQ G MGPKG PG +G PG
Sbjct: 179 QDGAAGPPGPPGPPGARGPPGDTGKDGPRGAQGPAGPKGEPGQDGEMGPKGPPGPKGEPG 238

Query: 593 LPG---------PPGPPG 601
           +PG          PGPPG
Sbjct: 239 VPGKKGDDGTPSQPGPPG 256



 Score =  125 bits (313), Expect = 1e-28
 Identities = 68/157 (43%), Positives = 78/157 (49%), Gaps = 7/157 (4%)

Query: 454 ILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPV 513
           IL    GPPGP+G  G  G+ G  G  G  G PG  G  GP+G +G PGE GP G +G  
Sbjct: 315 ILDALKGPPGPQGPPGPPGIPGAKGELGLPGAPGIDGEKGPKGQKGDPGEPGPAGLKGEA 374

Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDI-------GPPGPEGPPGSPGPSGPQGKPGI 566
           G  G  GL G+ G  G  G       +  +       GPPGP GPPG  G  G QG  G+
Sbjct: 375 GEMGLSGLPGADGLKGEKGESASDSLQESLAQLIVEPGPPGPPGPPGPMGLQGIQGPKGL 434

Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G  G  G  G  GP G PG  GPPGL G PG  G +
Sbjct: 435 DGAKGEKGASGERGPSGLPGPVGPPGLIGLPGTKGEK 471



 Score =  125 bits (313), Expect = 1e-28
 Identities = 74/165 (44%), Positives = 87/165 (52%), Gaps = 22/165 (13%)

Query: 456 RGAPGPPGPRGFKGD---MGVKGPVGGRGPKGDPG---------SLGPL----GPQGPQG 499
           +G PG PGP G KG+   MG+ G  G  G KG+ G         SL  L    GP GP G
Sbjct: 359 KGDPGEPGPAGLKGEAGEMGLSGLPGADGLKGEKGESASDSLQESLAQLIVEPGPPGPPG 418

Query: 500 QPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD---IGPPGPEGPPGSPG 556
            P   GP+G +G  GP+G  G KG KG+ G  GP G PGP G    IG PG +G  G PG
Sbjct: 419 PP---GPMGLQGIQGPKGLDGAKGEKGASGERGPSGLPGPVGPPGLIGLPGTKGEKGRPG 475

Query: 557 PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
             G  G PG  G+ G   +RG  G +G PG +G  G  G PGPPG
Sbjct: 476 EPGLDGFPGPRGEKGDRSERGEKGERGVPGRKGVKGQKGEPGPPG 520



 Score =  106 bits (265), Expect = 5e-23
 Identities = 63/152 (41%), Positives = 78/152 (51%), Gaps = 20/152 (13%)

Query: 447 EILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP 506
           E L  + +  G PGPPGP G  G  G++GP G  G KG+            +G  GE GP
Sbjct: 402 ESLAQLIVEPGPPGPPGPPGPMGLQGIQGPKGLDGAKGE------------KGASGERGP 449

Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI 566
            G  GPVGP G  GL G+KG       +G+PG  G  G PGP G  G     G +G+ G+
Sbjct: 450 SGLPGPVGPPGLIGLPGTKGE------KGRPGEPGLDGFPGPRGEKGDRSERGEKGERGV 503

Query: 567 AGKTGSPGQRGAMGPKG--EPGIQGPPGLPGP 596
            G+ G  GQ+G  GP G  +P   GP GLP P
Sbjct: 504 PGRKGVKGQKGEPGPPGLDQPCPVGPDGLPVP 535



 Score = 90.1 bits (222), Expect = 5e-18
 Identities = 40/75 (53%), Positives = 47/75 (62%)

Query: 529 GTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQ 588
           G  G RG+PG +GD GPPG  G  G PGP G  GKPG+ G  G  G  G  GP+G+ G  
Sbjct: 121 GPPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDGKPGLPGPKGEKGAPGDFGPRGDQGQD 180

Query: 589 GPPGLPGPPGPPGSQ 603
           G  G PGPPGPPG++
Sbjct: 181 GAAGPPGPPGPPGAR 195



 Score = 87.8 bits (216), Expect = 3e-17
 Identities = 47/94 (50%), Positives = 52/94 (55%), Gaps = 3/94 (3%)

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572
           V P G PG +G  G  G  GP GQ G  G  GP G +G PG PGP G +G PG  G  G 
Sbjct: 117 VCPPGPPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDGKPGLPGPKGEKGAPGDFGPRGD 176

Query: 573 PGQRGAMGPKGEPG---IQGPPGLPGPPGPPGSQ 603
            GQ GA GP G PG    +GPPG  G  GP G+Q
Sbjct: 177 QGQDGAAGPPGPPGPPGARGPPGDTGKDGPRGAQ 210


>gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens]
          Length = 1142

 Score =  153 bits (387), Expect = 4e-37
 Identities = 85/179 (47%), Positives = 102/179 (56%), Gaps = 32/179 (17%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP---LGPQGPQGQPGEAGPVGERGP 512
           +G PG P  +G KGD G  G +G +G KG+PG  GP   +G  G +GQ G AG +G RGP
Sbjct: 479 KGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGP 538

Query: 513 VGPRGFP---------GLKGSKGS-FGTGGPRGQPGPKGDIGPPGP--------EGPPGS 554
            G  G P         G+KG KG   G  GP G PGPKG+ GPPG         +G PG+
Sbjct: 539 PGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGA 598

Query: 555 PGPSGPQGKPGIAGKTGS-----------PGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           PGP GP+G+ G+ G  GS           PG+ GA GP GEPGIQGP GLPG PG PG+
Sbjct: 599 PGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGT 657



 Score =  138 bits (348), Expect = 1e-32
 Identities = 76/167 (45%), Positives = 86/167 (51%), Gaps = 15/167 (8%)

Query: 451  NVTILRGAPGPPGPRGFKGDMGVKGPV------------GGRGPKGDPGSLGPLGPQGPQ 498
            NV    G PGPPGP+G  G +G  G +            G RGP G PG  G  G  G  
Sbjct: 836  NVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAP 895

Query: 499  GQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS 558
            G PG  G  GERGPVG  GFPG +G  G  G  G  G PG +G +G PG  GP G  G  
Sbjct: 896  GPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQ 955

Query: 559  GPQGKPGIAGKTGSP---GQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
            G  G  G  G+ G P   G +GA+GP G PG +G  G PG  GPPGS
Sbjct: 956  GIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGS 1002



 Score =  135 bits (340), Expect = 1e-31
 Identities = 80/181 (44%), Positives = 87/181 (48%), Gaps = 32/181 (17%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPG----------SL-------------GP 491
           L G  G PGP G KG+ G  GP G  GP G PG          SL             GP
Sbjct: 784 LMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGP 843

Query: 492 LGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP 551
            GP GP+G PG  G  G  G  G  GFPG+KG +G  G  G  G  G  G  GPPG  G 
Sbjct: 844 PGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGE 903

Query: 552 PGS---------PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           PG          PGP GP GKPGI GK G PG +G MG  G+ G +G  G  G PG  GS
Sbjct: 904 PGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGS 963

Query: 603 Q 603
           Q
Sbjct: 964 Q 964



 Score =  132 bits (333), Expect = 7e-31
 Identities = 71/146 (48%), Positives = 77/146 (52%), Gaps = 3/146 (2%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           +G  G PG  G  G  G KG  G  G  G PG  G  G QG +G  GE G  GE+G  G 
Sbjct: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
               GL G  G  G  GP G PGPKG+ G  GP GPP  PG  G QG  G  GK G  G+
Sbjct: 351 PALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGR 410

Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPG 601
           RG  GP G+P   GPPG PGPPG  G
Sbjct: 411 RGKTGPPGKP---GPPGPPGPPGIQG 433



 Score =  131 bits (330), Expect = 2e-30
 Identities = 78/172 (45%), Positives = 86/172 (50%), Gaps = 26/172 (15%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG---PVGERGP 512
           RG PG PG +G +G  G+ G  G  GP G PG +G  G  GP G  GE G   P G+ GP
Sbjct: 752 RGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGP 811

Query: 513 VGPRGFP-----------GLKGSKGSFGTGGPRGQPGPKGDIGP---------PGPEGPP 552
            GP G P            +KG        GP G PGPKGD GP         PG EG P
Sbjct: 812 PGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFP 871

Query: 553 GSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPP---GLPGPPGPPG 601
           G  G  GP G PGIAG +G PG  G  G  GEPG +GP    G PGP GP G
Sbjct: 872 GVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSG 923



 Score =  130 bits (328), Expect = 3e-30
 Identities = 75/177 (42%), Positives = 90/177 (50%), Gaps = 31/177 (17%)

Query: 450 RNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDP------GSLGPL----------- 492
           R +  L G PG PG  G  G     G  G  GP GDP      G +G L           
Sbjct: 646 RGLPGLPGTPGTPGNDGVPGR---DGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQAS 702

Query: 493 --------GPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIG 544
                   G +G  G+PG+   +  +G +GPRG PG+ G +G  G+ G RG PG  G+ G
Sbjct: 703 VPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKG 762

Query: 545 PPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
             G +G PG PG  GP G PG+ G+TG PG  GA   KGE G  GPPG PGPPGPPG
Sbjct: 763 DEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGA---KGEKGSDGPPGKPGPPGPPG 816



 Score =  129 bits (325), Expect = 6e-30
 Identities = 72/171 (42%), Positives = 86/171 (50%), Gaps = 25/171 (14%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDP------GSLGPL---------------- 492
           L G PG PG  G  G  G  G  G  GP GDP      G +G L                
Sbjct: 648 LPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLK 707

Query: 493 ---GPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPE 549
              G +G  G+PG+   +  +G +GPRG PG+ G +G  G+ G RG PG  G+ G  G +
Sbjct: 708 SNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQ 767

Query: 550 GPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPP 600
           G PG PG  GP G PG+ G+TG PG  GA G KG  G  G PG PGPPG P
Sbjct: 768 GIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIP 818



 Score =  120 bits (301), Expect = 4e-27
 Identities = 69/167 (41%), Positives = 82/167 (49%), Gaps = 26/167 (15%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G  GPPGP+G KGD G  GP    G  G  G  GP G +G +G+ G+ GP G+ GP GP 
Sbjct: 367 GPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPP 426

Query: 517 GFPGLKG--------------------SKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPG 556
           G PG++G                    + G  G  G  G PG  G +GP G +G PG P 
Sbjct: 427 GPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPF 486

Query: 557 PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
             G +      G  G PG  G+ G KGEPG  GPPGL G PG  G Q
Sbjct: 487 TKGEK------GDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQ 527



 Score =  120 bits (300), Expect = 5e-27
 Identities = 79/207 (38%), Positives = 89/207 (42%), Gaps = 63/207 (30%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG-- 514
            G PG PG RG  GD+G  GP G  G  G  G  G  G QG  G+PG+ GP GERG  G  
Sbjct: 899  GVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIP 958

Query: 515  -------PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPG----------- 556
                    RG PGL G KG+ G   P G PG KG +G PG +GPPGSPG           
Sbjct: 959  GDRGSQGERGKPGLTGMKGAIG---PMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSF 1015

Query: 557  ---------------------------------------PSGPQGKPGIAGKTGSPGQRG 577
                                                     GP GK G+ G  G PG +G
Sbjct: 1016 EEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQG 1075

Query: 578  AMGPKGEPGIQGPPGLPGPPGPPGSQS 604
              G KGE G  G  GLPG PG PG+ +
Sbjct: 1076 YRGQKGERGEPGI-GLPGSPGLPGTSA 1101



 Score =  117 bits (293), Expect = 3e-26
 Identities = 67/161 (41%), Positives = 74/161 (45%), Gaps = 11/161 (6%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           +G  G  G  G    M  KG +G RGP G PG  GP G +G +G PG  G  G+ G  G 
Sbjct: 710 KGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGI 769

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP----------- 564
            G PG  G  G  G  G  G PGP G  G  G +GPPG PGP GP G P           
Sbjct: 770 PGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLY 829

Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
            I G    P   G  GP G  G  GP G PG  G PG + F
Sbjct: 830 KIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGF 870



 Score =  116 bits (291), Expect = 5e-26
 Identities = 76/203 (37%), Positives = 89/203 (43%), Gaps = 59/203 (29%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
           L GAPG PG +G +G  G KG  G +G +G+ G     G  G  G  G+ GP    GP G
Sbjct: 317 LHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALAGLNGENGLKGDLGP---HGPPG 373

Query: 515 PRGF------PGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGI-- 566
           P+G       PG     GS G  GP+G PG +G  G  G  GPPG PGP GP G PGI  
Sbjct: 374 PKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQG 433

Query: 567 ---------------------------AGKTGSPGQRGAMGPK----------------- 582
                                       G+TG PG  G++GPK                 
Sbjct: 434 IHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGD 493

Query: 583 -GEPGI---QGPPGLPGPPGPPG 601
            GEPG+   QG  G PG PGPPG
Sbjct: 494 RGEPGVIGSQGVKGEPGDPGPPG 516



 Score =  115 bits (288), Expect = 1e-25
 Identities = 62/148 (41%), Positives = 78/148 (52%), Gaps = 18/148 (12%)

Query: 477 VGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQ 536
           +  +G  G PG+ G  G +G +G+PGE G  G  G  G +G  G +GSKG  G  G +G+
Sbjct: 288 IPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGE 347

Query: 537 PGP------------KGDIGPPGPEGPPGSPGPSGPQGKP------GIAGKTGSPGQRGA 578
            G             KGD+GP GP GP G  G +GP G P      GI G  G PG+ G 
Sbjct: 348 KGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQ 407

Query: 579 MGPKGEPGIQGPPGLPGPPGPPGSQSFY 606
            G +G+ G  G PG PGPPGPPG Q  +
Sbjct: 408 RGRRGKTGPPGKPGPPGPPGPPGIQGIH 435



 Score =  114 bits (286), Expect = 2e-25
 Identities = 78/218 (35%), Positives = 94/218 (43%), Gaps = 73/218 (33%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE------- 509
           G  GPPG  G  G+ G+ G  G +G KGDPG  G +GP G  G  GEAGP G+       
Sbjct: 534 GPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG--GIIGPPGLPGPKGEAGPPGKSLPGEPG 591

Query: 510 ----------RGPVGPRGFPGLKGSKGSFG---------TG--GPRGQPG---PKGDIGP 545
                     RGP G RG PG+ GS G  G         TG  GP G+PG   P+G  G 
Sbjct: 592 LDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGL 651

Query: 546 PGPEGPPGSPGPSGPQGKPGIAGK------------------------------------ 569
           PG  G PG+ G  G  GKPG+ G                                     
Sbjct: 652 PGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKG 711

Query: 570 ----TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
                G PG+  +M  KG+ G +GPPG+PG  GP GS+
Sbjct: 712 EEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSK 749



 Score =  113 bits (283), Expect = 4e-25
 Identities = 74/197 (37%), Positives = 87/197 (44%), Gaps = 51/197 (25%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGP--QGQPGEAGPVGERGPV 513
           +  PG PG  G  G  G +GP G RG  G  GS G +GPQG    G+ G  GP GE G  
Sbjct: 584 KSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQ 643

Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP------------------------- 548
           GPRG PGL G+ G+ G  G  G+ G  G  GPPG                          
Sbjct: 644 GPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASV 703

Query: 549 ---------EGPPGSPGPS---------GPQGKPGIAGKTGSPGQRGAM------GPKGE 584
                    EG  G PG           GP+G PGI G+ G  G +G        G KG+
Sbjct: 704 PGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGD 763

Query: 585 PGIQGPPGLPGPPGPPG 601
            G+QG PG+PG PGP G
Sbjct: 764 EGLQGIPGIPGAPGPTG 780



 Score =  112 bits (281), Expect = 8e-25
 Identities = 80/229 (34%), Positives = 91/229 (39%), Gaps = 87/229 (37%)

Query: 457  GAPGPP---------GP---RGFKGDMGVKGPVGGRGPKGDPGS---LGPLGPQGPQGQP 501
            GAPGPP         GP    GF G  G  G  G  G  G PG+   +G  G +GP+G+ 
Sbjct: 893  GAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGER 952

Query: 502  GEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS------- 554
            G+ G  G+RG  G RG PGL G KG+    GP G PG KG +G PG +GPPGS       
Sbjct: 953  GDQGIPGDRGSQGERGKPGLTGMKGAI---GPMGPPGNKGSMGSPGHQGPPGSPGIPGIP 1009

Query: 555  ----------------------------------------------PGPSGPQGKPGIAG 568
                                                          PGP G  G PG  G
Sbjct: 1010 ADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPG 1069

Query: 569  KTGSPGQRGAMGPKGEPGI----------------QGPPGLPGPPGPPG 601
              G  G RG  G +GEPGI                 G PG PGP GPPG
Sbjct: 1070 DPGPQGYRGQKGERGEPGIGLPGSPGLPGTSALGLPGSPGAPGPQGPPG 1118



 Score =  109 bits (272), Expect = 8e-24
 Identities = 68/184 (36%), Positives = 80/184 (43%), Gaps = 41/184 (22%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLG---PLGPQGPQGQPGEAGPVGERG 511
            + G PG  GP+G +GD G+ G  G +G +G PG  G    +GP GP G  G  G  G +G
Sbjct: 939  IMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQG 998

Query: 512  PVGPRGFPGLKGSKGSF-----------------------------------GTGGPRGQ 536
            P G  G PG+     SF                                      G  G 
Sbjct: 999  PPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGP 1058

Query: 537  PGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRG--AMGPKGEPGIQGPPGLP 594
            PG  G  GPPG  GP G  G  G +G+PGI G  GSPG  G  A+G  G PG  GP G P
Sbjct: 1059 PGKDGLPGPPGDPGPQGYRGQKGERGEPGI-GLPGSPGLPGTSALGLPGSPGAPGPQGPP 1117

Query: 595  GPPG 598
            GP G
Sbjct: 1118 GPSG 1121



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 53/159 (33%), Positives = 64/159 (40%), Gaps = 49/159 (30%)

Query: 452  VTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPG------------------------ 487
            +T ++GA GP GP G KG MG  G  G  G  G PG                        
Sbjct: 972  LTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFE 1031

Query: 488  -----------------SLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGT 530
                             +    G  GP G+ G  GP G+    GP+G+ G KG +G  G 
Sbjct: 1032 ERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGD---PGPQGYRGQKGERGEPGI 1088

Query: 531  GGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGK 569
            G P G PG  G        G PGSPG  GPQG PG +G+
Sbjct: 1089 GLP-GSPGLPG----TSALGLPGSPGAPGPQGPPGPSGR 1122



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 26/62 (41%), Positives = 30/62 (48%), Gaps = 10/62 (16%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVG----------GRGPKGDPGSLGPLGPQGPQGQPGEA 504
            L G PG PGP+G++G  G +G  G          G    G PGS G  GPQGP G  G  
Sbjct: 1064 LPGPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRC 1123

Query: 505  GP 506
             P
Sbjct: 1124 NP 1125


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score =  153 bits (386), Expect = 5e-37
 Identities = 75/151 (49%), Positives = 85/151 (56%), Gaps = 6/151 (3%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE------AGPVGER 510
           G PG  G RG  G +G  GP G  G +G+ G+ GP GP GP+G PGE      AGP G  
Sbjct: 667 GNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFA 726

Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKT 570
           GP G  G PG KG +G+ G  G  G  GP G +G  GP GP G PGP+G +G  G  G T
Sbjct: 727 GPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMT 786

Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           G PG  G  GP G  GI GPPG PGP G  G
Sbjct: 787 GFPGAAGRTGPPGPSGISGPPGPPGPAGKEG 817



 Score =  152 bits (384), Expect = 9e-37
 Identities = 77/145 (53%), Positives = 85/145 (58%), Gaps = 3/145 (2%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            GAPGP GP G  G  G +G  G  GP G  G++GP GP GPQG  G+ G  GE+GP   R
Sbjct: 961  GAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGP---R 1017

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
            G PGLKG  G  G  G  G  G +G  G  GP GP G  GPSGP GK G  G  G+ G  
Sbjct: 1018 GLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPA 1077

Query: 577  GAMGPKGEPGIQGPPGLPGPPGPPG 601
            G  GP+G  G  GPPG PGPPGPPG
Sbjct: 1078 GIRGPQGHQGPAGPPGPPGPPGPPG 1102



 Score =  150 bits (380), Expect = 2e-36
 Identities = 74/145 (51%), Positives = 80/145 (55%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           GAPGP G  G +G+ G  GP G  GP+G PG  G +GP GP G  G AG  G+ G  G R
Sbjct: 682 GAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGER 741

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           G  G KG  G  G  GP G  GP G  GPPGP G  G  GP G  G PG AG+TG PG  
Sbjct: 742 GAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPS 801

Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPG 601
           G  GP G PG  G  GL GP G  G
Sbjct: 802 GISGPPGPPGPAGKEGLRGPRGDQG 826



 Score =  147 bits (371), Expect = 3e-35
 Identities = 75/150 (50%), Positives = 89/150 (59%), Gaps = 12/150 (8%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G  GPPG RG  G  GV+GP G  G  G+PG +GP   +G  G PG  GP G+ GPV   
Sbjct: 415 GVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGP---RGLPGSPGNIGPAGKEGPV--- 468

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP--- 573
           G PG+ G  G  G  G RG+P   G+IG PGP+GP G PG +G +G  G+AG  G+P   
Sbjct: 469 GLPGIDGRPGPIGPAGARGEP---GNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPD 525

Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           G  GA GP G  G+QG  G  GPPGPPG Q
Sbjct: 526 GNNGAQGPPGPQGVQGGKGEQGPPGPPGFQ 555



 Score =  144 bits (364), Expect = 2e-34
 Identities = 75/150 (50%), Positives = 81/150 (54%), Gaps = 3/150 (2%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PG  GPRG  G  G  GP G  GP G PG  G  GP GP G  GE G +G  GP GP 
Sbjct: 442 GEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPT 501

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGD---IGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
           G PG  G KG  G  G RG PGP G+    GPPGP+G  G  G  GP G PG  G  G  
Sbjct: 502 GDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPS 561

Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           G  G +G  GE G+ G  GLPGP GP G +
Sbjct: 562 GPAGEVGKPGERGLHGEFGLPGPAGPRGER 591



 Score =  143 bits (360), Expect = 5e-34
 Identities = 82/184 (44%), Positives = 89/184 (48%), Gaps = 39/184 (21%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGR---------------GPKGDPGSLGPLGPQGPQGQP 501
           GAPG PGPRG  G +G  G  G R               G KG+PGS GP GP GP G+ 
Sbjct: 319 GAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEE 378

Query: 502 GEAGPVGERGPVGPRGFPGLKGS------------------KGSFGTGGPRGQPGPKGDI 543
           G+ GP GE G  GP G PGL+GS                   GS G  GP G  GP GD 
Sbjct: 379 GKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDA 438

Query: 544 GPP------GPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP 597
           G P      GP G PGSPG  GP GK G  G  G  G+ G +GP G  G  G  G PGP 
Sbjct: 439 GRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPK 498

Query: 598 GPPG 601
           GP G
Sbjct: 499 GPTG 502



 Score =  142 bits (359), Expect = 7e-34
 Identities = 72/153 (47%), Positives = 91/153 (59%), Gaps = 6/153 (3%)

Query: 455 LRGAPGPPGPRGFKGDMGVKG------PVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG 508
           L G+PG  GP G +G +G+ G      P+G  G +G+PG++G  GP+GP G PG+ G  G
Sbjct: 452 LPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKG 511

Query: 509 ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAG 568
             G  G RG PG  G+ G+ G  GP+G  G KG+ GPPGP G  G PGPSGP G+ G  G
Sbjct: 512 HAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPG 571

Query: 569 KTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           + G  G+ G  GP G  G +GPPG  G  GP G
Sbjct: 572 ERGLHGEFGLPGPAGPRGERGPPGESGAAGPTG 604



 Score =  142 bits (358), Expect = 9e-34
 Identities = 72/149 (48%), Positives = 85/149 (57%), Gaps = 3/149 (2%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PGP GPRG +G  G  G  G  GP G  G  GP GP G +G+PG  G VG  GP GP 
Sbjct: 580 GLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPS 639

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           G PG +G+ G  G  G +G+PG +G+IG PG +G  G+P   G  G PG AG TG  G+ 
Sbjct: 640 GLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAP---GAVGAPGPAGATGDRGEA 696

Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
           GA GP G  G +G PG  G  GP G   F
Sbjct: 697 GAAGPAGPAGPRGSPGERGEVGPAGPNGF 725



 Score =  142 bits (357), Expect = 1e-33
 Identities = 74/158 (46%), Positives = 86/158 (54%), Gaps = 9/158 (5%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
           ++G PG PG  G  G  G +G  G RG  G PG  G  G  G  G  G AGP+G  GP G
Sbjct: 197 VKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPG 256

Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPP---GPEGPPGSPGPS------GPQGKPG 565
             G PG KG  G+ G  GP G  GP+G++G P   GP GPPG+PG +      G  G PG
Sbjct: 257 FPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPG 316

Query: 566 IAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           +AG  G PG RG  GP G  G  G  GL G PGP GS+
Sbjct: 317 VAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSK 354



 Score =  141 bits (355), Expect = 2e-33
 Identities = 75/163 (46%), Positives = 87/163 (53%), Gaps = 18/163 (11%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           GA G PGP+GF+G  G  G  G  GP G  G  GP G  G  G PG+ G  GERG VGP+
Sbjct: 103 GAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQ 162

Query: 517 ---------GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA 567
                    G PG KG +G  G  G +GQPG  G  G PG  G  G+PG +G +G PG  
Sbjct: 163 GARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGER 222

Query: 568 GKTGSPGQRGA---------MGPKGEPGIQGPPGLPGPPGPPG 601
           G+ G+PG  GA         +GP G  G  GPPG PG PGP G
Sbjct: 223 GRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKG 265



 Score =  141 bits (355), Expect = 2e-33
 Identities = 77/156 (49%), Positives = 86/156 (55%), Gaps = 9/156 (5%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG---ERGP 512
           RG  GPPG  GF G  G  GP G  G  G PG  GP G +G +G  G+ GPVG   E G 
Sbjct: 777 RGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGA 836

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS------PGPSGPQGKPGI 566
           VGP GF G KG  G  GT GP G PGP+G +G PG  G PGS      PG +G  G+PG 
Sbjct: 837 VGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGP 896

Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
            G  G PG RG  G  G PG+ G PG  G  G PG+
Sbjct: 897 LGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGN 932



 Score =  140 bits (352), Expect = 4e-33
 Identities = 72/158 (45%), Positives = 89/158 (56%), Gaps = 12/158 (7%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP------QGPQGQPGEAGPVGER 510
           G  GPPGP G  G  G++GP G +GP G  G +G +GP      +GP G+ G AGP G  
Sbjct: 802 GISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTP 861

Query: 511 GPVGPRGFPGL------KGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564
           GP G  G PG+      +G +G  G  G  G+PGP G  GPPG  GPPG+ G  G  G P
Sbjct: 862 GPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAP 921

Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           G AG+ G+PG  G  G  G+PG +G  G PG  GP G+
Sbjct: 922 GEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGA 959



 Score =  138 bits (348), Expect = 1e-32
 Identities = 67/147 (45%), Positives = 79/147 (53%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G  GP GP G  G+ G  G  GG+G KG+PG  G +G  G  G  G  G VG  GP G  
Sbjct: 631 GTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGAT 690

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           G  G  G+ G  G  GPRG PG +G++GP GP G  G  G +G  G  G  G  G  G+ 
Sbjct: 691 GDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGEN 750

Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           G +GP G  G  GP G  GPPGP GS+
Sbjct: 751 GVVGPTGPVGAAGPAGPNGPPGPAGSR 777



 Score =  138 bits (347), Expect = 2e-32
 Identities = 69/147 (46%), Positives = 80/147 (54%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           +G  GPPGP GF+G  G  GP G  G  G+ G  G  G  GP G  GE GP GE G  GP
Sbjct: 543 KGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGP 602

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
            G  G +G  G  G  G +G+PG  G +G  GP GP G PG  G  G PG  G+ G PG 
Sbjct: 603 TGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGL 662

Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           RG +G  G  G +G PG  G PGP G+
Sbjct: 663 RGEIGNPGRDGARGAPGAVGAPGPAGA 689



 Score =  137 bits (346), Expect = 2e-32
 Identities = 75/148 (50%), Positives = 79/148 (53%), Gaps = 3/148 (2%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           GAPGP G RG  G +G  GP G  G  G PG  G  GP+G  G  G AGP G  GP G  
Sbjct: 226 GAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEV 285

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           G PGL G  G  G  G  G  G KG  G PG  G PG PGP G  G  G AG TG+ G  
Sbjct: 286 GLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLV 345

Query: 577 GAMGP---KGEPGIQGPPGLPGPPGPPG 601
           G  GP   KGE G +G PG  GP GPPG
Sbjct: 346 GEPGPAGSKGESGNKGEPGSAGPQGPPG 373



 Score =  137 bits (345), Expect = 3e-32
 Identities = 74/156 (47%), Positives = 79/156 (50%), Gaps = 9/156 (5%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           RG  GP GP GF G  G  G  G +G +G  G  G  G  GP G  G AGP G  GP GP
Sbjct: 714 RGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGP 773

Query: 516 ---RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572
              RG  G  G  G  G  G  G PGP G  GPPGP GP G  G  GP+G  G  G+TG 
Sbjct: 774 AGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGE 833

Query: 573 ------PGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
                 PG  G  GP GE G  GPPG PGP G  G+
Sbjct: 834 VGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGA 869



 Score =  137 bits (345), Expect = 3e-32
 Identities = 76/152 (50%), Positives = 81/152 (53%), Gaps = 9/152 (5%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G  GPPGP G +GD    GP G  G  G  G  GP GP G  G PG  GP G+ G  GPR
Sbjct: 766 GPNGPPGPAGSRGD---GGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPR 822

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           G  G  G  G  G  GP G  G KG  G  G  GPPG+PGP G  G PGI G  GS G+R
Sbjct: 823 GDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGER 882

Query: 577 ------GAMGPKGEPGIQGPPGLPGPPGPPGS 602
                 GA+G  G  GI GPPG  GPPG  GS
Sbjct: 883 GLPGVAGAVGEPGPLGIAGPPGARGPPGAVGS 914



 Score =  136 bits (343), Expect = 5e-32
 Identities = 68/146 (46%), Positives = 78/146 (53%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           GAPG  G  G  G+ G  G  G RG  G+ G +G  GP G +G  G  GPVG  GP+G  
Sbjct: 193 GAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSA 252

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           G PG  G+ G  G  G  G  GP G  GP G  G PG  GP GP G PG  G TG+ G  
Sbjct: 253 GPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAA 312

Query: 577 GAMGPKGEPGIQGPPGLPGPPGPPGS 602
           G  G  G PG+ GP G+PGP G  G+
Sbjct: 313 GLPGVAGAPGLPGPRGIPGPVGAAGA 338



 Score =  134 bits (337), Expect = 2e-31
 Identities = 74/168 (44%), Positives = 89/168 (52%), Gaps = 21/168 (12%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGD---PGSLGPLGP---------QGPQGQPGEA 504
           G PG PGP+G  G +G  GP G  GP+G+   PG  GP+GP          G +G  G  
Sbjct: 256 GFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLP 315

Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564
           G  G  G  GPRG PG  G+ G+ G  G  G+PGP G  G  G +G PGS GP GP G  
Sbjct: 316 GVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPS 375

Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP---------GPPGSQ 603
           G  GK G  G+ G+ GP G PG++G PG  G P         GPPGS+
Sbjct: 376 GEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSR 423



 Score =  134 bits (336), Expect = 3e-31
 Identities = 72/163 (44%), Positives = 81/163 (49%), Gaps = 16/163 (9%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPG----------------SLGPLGPQGPQG 499
           RG  GPPGP G  G+ G  GP G  GP G PG                  GP+G  GP+G
Sbjct: 41  RGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRG 100

Query: 500 QPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSG 559
            PG AG  G +G  GP G PG  G  G  G  GP G PG  G+ G PG  G PG  G  G
Sbjct: 101 PPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVG 160

Query: 560 PQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           PQG  G  G  G PG +G  G  G  G++G PG PG  G PG+
Sbjct: 161 PQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGA 203



 Score =  132 bits (333), Expect = 7e-31
 Identities = 72/148 (48%), Positives = 77/148 (52%), Gaps = 3/148 (2%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PGP GP G  G  G KG  G  G +G PG  G  G QGP G  G  G  GE+GP GP 
Sbjct: 493 GFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPP 552

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQR 576
           GF GL G  G  G  G  G+ G  G+ G PGP GP G  GP G  G  G  G  GS G  
Sbjct: 553 GFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPS 612

Query: 577 GAMGP---KGEPGIQGPPGLPGPPGPPG 601
           G  GP   KGEPG+ G  G  GP GP G
Sbjct: 613 GPPGPDGNKGEPGVVGAVGTAGPSGPSG 640



 Score =  132 bits (333), Expect = 7e-31
 Identities = 73/161 (45%), Positives = 88/161 (54%), Gaps = 15/161 (9%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPV---GGRGPKGDPGSLGPLGPQGPQGQPGEA------GP 506
           +G PGPPG +G  G  G  G V   G RG  G+ G  GP GP+G +G PGE+      GP
Sbjct: 546 QGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGP 605

Query: 507 VGERGPVGP------RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGP 560
           +G RGP GP      +G PG+ G+ G+ G  GP G PG +G  G PG +G  G PG  G 
Sbjct: 606 IGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGE 665

Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G PG  G  G+PG  GA GP G  G +G  G  GP GP G
Sbjct: 666 IGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAG 706



 Score =  132 bits (332), Expect = 9e-31
 Identities = 77/173 (44%), Positives = 90/173 (52%), Gaps = 27/173 (15%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE------ 509
           +G  G PG  G KG  G+ G  G  GP G+ G+ GP GPQG QG  GE GP G       
Sbjct: 498 KGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGL 557

Query: 510 ---RGPVGPRGFPGLKGSKGSFGT---GGPRGQPGPKGDIGPPGPEGPPGSPGPSGP--- 560
               GP G  G PG +G  G FG     GPRG+ GP G+ G  GP GP GS GPSGP   
Sbjct: 558 PGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGP 617

Query: 561 ---QGKPGIAGKTGS---------PGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
              +G+PG+ G  G+         PG+RGA G  G  G +G PGL G  G PG
Sbjct: 618 DGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPG 670



 Score =  130 bits (328), Expect = 3e-30
 Identities = 71/146 (48%), Positives = 78/146 (53%), Gaps = 3/146 (2%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           RGA GP G RG  GD G  G  G  GP+G PGS G +GP G +G  G  G  G  GP+GP
Sbjct: 423 RGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGP 482

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
            G  G  G+ G  G  GP G PG  GD G  G  G  G+PGP G  G  G  G  G  G 
Sbjct: 483 AGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGG 542

Query: 576 RGAMGPKGEPGIQGPPGLPGPPGPPG 601
           +G  GP G PG Q   GLPGP GP G
Sbjct: 543 KGEQGPPGPPGFQ---GLPGPSGPAG 565



 Score =  130 bits (327), Expect = 3e-30
 Identities = 71/160 (44%), Positives = 82/160 (51%), Gaps = 15/160 (9%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAG----------- 505
           G  GP GP G +G++G+ G  G  GP G+PG+ G  G +G  G PG AG           
Sbjct: 271 GNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIP 330

Query: 506 -PVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGK- 563
            PVG  G  G RG  G  G  GS G  G +G+PG  G  GPPGP G  G  GP+G  G  
Sbjct: 331 GPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSA 390

Query: 564 --PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
             PG  G  GSPG RG  G  G  G+ GPPG  G  GP G
Sbjct: 391 GPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAG 430



 Score =  130 bits (327), Expect = 3e-30
 Identities = 70/150 (46%), Positives = 78/150 (52%), Gaps = 3/150 (2%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
           L G  GPPG  G  G  G KG  G  G  G PG  GP G  GP G  G  G  G  G  G
Sbjct: 290 LSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPG 349

Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGP---QGKPGIAGKTG 571
           P G  G  G+KG  G+ GP+G PGP G+ G  GP G  GS GP GP   +G PG  G  G
Sbjct: 350 PAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPG 409

Query: 572 SPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           + G+ G MGP G  G  GP G+ GP G  G
Sbjct: 410 ADGRAGVMGPPGSRGASGPAGVRGPNGDAG 439



 Score =  130 bits (327), Expect = 3e-30
 Identities = 73/160 (45%), Positives = 83/160 (51%), Gaps = 15/160 (9%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           GA G  G +G  G  GV G  G  GP+G PG +G  G  G +G  GE GP G +G  G +
Sbjct: 301 GANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNK 360

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP---GSPGPSGPQGKPGIAGKTGSP 573
           G PG  G +G  G  G  G+ GP G+ G  GP GPP   GSPG  G  G  G AG  G P
Sbjct: 361 GEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPP 420

Query: 574 GQRGAMGP------------KGEPGIQGPPGLPGPPGPPG 601
           G RGA GP             GEPG+ GP GLPG PG  G
Sbjct: 421 GSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIG 460



 Score =  129 bits (325), Expect = 6e-30
 Identities = 71/151 (47%), Positives = 80/151 (52%), Gaps = 6/151 (3%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            RG PG  G  G  G +G+ GP G RGP   PG++G  G  G  G+ G  G  G  GP G 
Sbjct: 882  RGLPGVAGAVGEPGPLGIAGPPGARGP---PGAVGSPGVNGAPGEAGRDGNPGNDGPPGR 938

Query: 516  RGFPGLKGSKGSFGTGGP---RGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572
             G PG KG +G  G  GP    G PGP G +GP G  G  G  GPSGP G  G  G  G 
Sbjct: 939  DGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGP 998

Query: 573  PGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
             G +G  G KGEPG +GP GLPG  G  G Q
Sbjct: 999  SGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQ 1029



 Score =  127 bits (318), Expect = 4e-29
 Identities = 68/152 (44%), Positives = 78/152 (51%), Gaps = 16/152 (10%)

Query: 463 GPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV-------------GE 509
           GP G +G  G +GP G  G  G+ G  GP GP GP G PG  G               G 
Sbjct: 33  GPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGP 92

Query: 510 RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGK 569
            G +GPRG PG  G+ G  G  GP G+PG  G  GP G  GP G PG +G  G P   GK
Sbjct: 93  MGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHP---GK 149

Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G PG+RG +GP+G  G  G PGLPG  G  G
Sbjct: 150 PGRPGERGVVGPQGARGFPGTPGLPGFKGIRG 181



 Score =  126 bits (317), Expect = 5e-29
 Identities = 73/158 (46%), Positives = 88/158 (55%), Gaps = 12/158 (7%)

Query: 457 GAPGPPGPRGFKG---DMGVKGPVGGRGPKG---DPGSLGPLGPQGPQGQPGEAGPVGER 510
           GA GPPG  G KG   + G  GP G  GP+G    PG LG  G +G +G PG AG VGE 
Sbjct: 835 GAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEP 894

Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP---GSPGPSGPQGKP--- 564
           GP+G  G PG +G  G+ G+ G  G PG  G  G PG +GPP   G PG  G +G P   
Sbjct: 895 GPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNI 954

Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           G  G  G+PG  G +GP G+ G +G  G  GP GP G+
Sbjct: 955 GPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGA 992



 Score =  125 bits (315), Expect = 9e-29
 Identities = 71/156 (45%), Positives = 80/156 (51%), Gaps = 9/156 (5%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            + G PG  GP G  G  GV G  G  G  G+PG+ GP G  G  G  GE G  G  GPVG
Sbjct: 899  IAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVG 958

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPP---GPEGPPGSPGPSGPQGKPGIAGKTG 571
              G PG  G  G  G  G RG+ GP G +GP    GP GP G  G  G +G+PG  G  G
Sbjct: 959  AAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRG 1018

Query: 572  SPGQRGAMGPKGEPGI------QGPPGLPGPPGPPG 601
             PG +G  G +G PGI      QG PG  GP GP G
Sbjct: 1019 LPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRG 1054



 Score =  117 bits (293), Expect = 3e-26
 Identities = 68/150 (45%), Positives = 77/150 (51%), Gaps = 28/150 (18%)

Query: 474 KGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGS--------- 524
           KGP G RGP+G+ G      P GP G+ GE GP G  GP GP G PGL G+         
Sbjct: 32  KGPAGDRGPRGERG------PPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKG 85

Query: 525 ----KGSFGTGGPRGQPG------PKGDIGPPGPEGPPGSPGPS---GPQGKPGIAGKTG 571
                G  G  GPRG PG      P+G  GP G  G PG  GP+   GP G PG AG+ G
Sbjct: 86  VGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDG 145

Query: 572 SPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            PG+ G  G +G  G QG  G PG PG PG
Sbjct: 146 HPGKPGRPGERGVVGPQGARGFPGTPGLPG 175



 Score =  108 bits (271), Expect = 1e-23
 Identities = 58/124 (46%), Positives = 60/124 (48%), Gaps = 18/124 (14%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP------------------LGPQGPQ 498
            G  GP GP G  G  G  GP G RG KG+PG  GP                   G  G Q
Sbjct: 982  GPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQ 1041

Query: 499  GQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS 558
            G PG  GP G RGP GP G  G  G  G  GT GP G  GP+G  GP GP GPPG PGP 
Sbjct: 1042 GAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPP 1101

Query: 559  GPQG 562
            G  G
Sbjct: 1102 GVSG 1105



 Score = 97.8 bits (242), Expect = 3e-20
 Identities = 57/134 (42%), Positives = 63/134 (47%), Gaps = 25/134 (18%)

Query: 495 QGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGP--------------- 539
           Q  Q +    GP G+RGP G RG PG  G  G  G  GP G PGP               
Sbjct: 23  QSLQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYD 82

Query: 540 -------KGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ---RGAMGPKGEPGIQG 589
                   G +G  GP GPPG+ G  GPQG  G AG+ G PGQ    GA GP G PG  G
Sbjct: 83  GKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAG 142

Query: 590 PPGLPGPPGPPGSQ 603
             G PG PG PG +
Sbjct: 143 EDGHPGKPGRPGER 156



 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 49/133 (36%), Positives = 60/133 (45%), Gaps = 21/133 (15%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQ------GPQGQPGEAGPVGE 509
            +G  G PG +G  G  G+ G  G  G +G PGS+GP GP+      GP G+ G  G  G 
Sbjct: 1014 KGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGT 1073

Query: 510  RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGK 569
             GP G R               GP+G  GP G  GPPGP GPPG  G     G  G   +
Sbjct: 1074 VGPAGIR---------------GPQGHQGPAGPPGPPGPPGPPGVSGGGYDFGYDGDFYR 1118

Query: 570  TGSPGQRGAMGPK 582
               P    ++ PK
Sbjct: 1119 ADQPRSAPSLRPK 1131



 Score = 76.6 bits (187), Expect = 6e-14
 Identities = 39/83 (46%), Positives = 46/83 (55%), Gaps = 3/83 (3%)

Query: 525 KGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP--GQRGAMGPK 582
           KG  G  GPRG+ GP G  G  G +GP G PGP GP G PG+ G   +   G+   +GP 
Sbjct: 32  KGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGP- 90

Query: 583 GEPGIQGPPGLPGPPGPPGSQSF 605
           G  G+ GP G PG  G PG Q F
Sbjct: 91  GPMGLMGPRGPPGAAGAPGPQGF 113


>gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]
          Length = 1714

 Score =  152 bits (385), Expect = 7e-37
 Identities = 76/147 (51%), Positives = 89/147 (60%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
           L+G  GPPGP GF GD+G+ G  G  GPKG  G+ GP GP G +G  GE GP+G  G +G
Sbjct: 760 LQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELG 819

Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574
           PRG PG KG  G  G  G +G+ G +G+IG  G  GP G PG  G  G  G  G+ GSPG
Sbjct: 820 PRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPG 879

Query: 575 QRGAMGPKGEPGIQGPPGLPGPPGPPG 601
             G  G KG  G  GPPG+PGP GP G
Sbjct: 880 PLGPQGEKGVMGYPGPPGVPGPIGPLG 906



 Score =  142 bits (358), Expect = 9e-34
 Identities = 79/167 (47%), Positives = 88/167 (52%), Gaps = 21/167 (12%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           RG PG  G +GFKG  G  G  G RGP G  GS G +G  GP G PG  G VG  GP+GP
Sbjct: 635 RGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGP 694

Query: 516 ------------RGFPGLKGSKGSFGTGGPRGQ---PGPKGDIGPPGPEGPPGSPGPSGP 560
                       +G PG+KG KG  GT G  G+   PG KG +G PGP G  G  GPSG 
Sbjct: 695 AGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQ 754

Query: 561 QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP------GPPGPPG 601
            G PG+ G +G PG  G  G  G PG  GP G        GPPGPPG
Sbjct: 755 TGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPG 801



 Score =  141 bits (356), Expect = 2e-33
 Identities = 79/175 (45%), Positives = 95/175 (54%), Gaps = 30/175 (17%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PG  G  G  G  G++G  G  G  GDPG  GP GP GP+G PG+ G  G+ GP GP+
Sbjct: 729 GYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPK 788

Query: 517 GF---------PGLKGSKG------SFGTGGPRGQPGPKGDIGPPGPEGPPGSP------ 555
           G          PGLKG++G      +FG  GPRG+PG KG  G PGPEG  G        
Sbjct: 789 GLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNI 848

Query: 556 ---GPSGPQGKPGIAGKTGSPGQR------GAMGPKGEPGIQGPPGLPGPPGPPG 601
              G +GP G PG  G TGS G++      G +GP+GE G+ G PG PG PGP G
Sbjct: 849 GKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIG 903



 Score =  140 bits (352), Expect = 4e-33
 Identities = 81/166 (48%), Positives = 96/166 (57%), Gaps = 24/166 (14%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP---LGPQGPQGQPGEAGPVGERGP- 512
            G PGP GP G  G +G +GP G +GPKG  GS GP   LG QG QG  GE G  G+RGP 
Sbjct: 897  GVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPH 956

Query: 513  --------VGPRGF---PGLKGSKGSFGTGGPRGQPGPKG---DIGPPGP---EGPPGSP 555
                     G RGF   PGL+G  GS G  G  G+PG +G   D+GPPG    EGPPG+ 
Sbjct: 957  GLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTE 1016

Query: 556  GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G SG QG+PG  G  G+ G   ++G  GEPG++G PG PG  G  G
Sbjct: 1017 GESGLQGEPGAKGDVGTAG---SVGGTGEPGLRGEPGAPGEEGLQG 1059



 Score =  138 bits (347), Expect = 2e-32
 Identities = 78/162 (48%), Positives = 91/162 (56%), Gaps = 15/162 (9%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG---- 511
            +G PG  G  G  G  G  GP G +G  G PGS G  GP+G QG PG+ G  G+RG    
Sbjct: 1314 QGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGA 1373

Query: 512  --PVGPRGFPGLKGSKGSFG----TG-----GPRGQPGPKGDIGPPGPEGPPGSPGPSGP 560
                GP G PGLKG  G +G    TG     GP+G  G  G +G  GP+GP G  G +GP
Sbjct: 1374 QGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGP 1433

Query: 561  QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
             G+ GI G TG  G RG  G +GE G QGP G PGPPGPPG+
Sbjct: 1434 LGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGA 1475



 Score =  135 bits (340), Expect = 1e-31
 Identities = 71/151 (47%), Positives = 82/151 (54%), Gaps = 6/151 (3%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG----- 511
           G+PG PG +G  G  G  GP G +G  G PG  G LGP+G +G PG  G  G +G     
Sbjct: 594 GSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFP 653

Query: 512 -PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKT 570
              G RG  GL GS G  G  GP G PG +G +GP GP GP G PGP G  G  G+ G  
Sbjct: 654 GDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIK 713

Query: 571 GSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           G  G++G  G  GEPG  G  G  G PGPPG
Sbjct: 714 GDKGEQGTAGELGEPGYPGDKGAVGLPGPPG 744



 Score =  134 bits (337), Expect = 2e-31
 Identities = 88/197 (44%), Positives = 100/197 (50%), Gaps = 51/197 (25%)

Query: 456  RGAPGPPGPRGFKGDM---------------------GVKGPVGGRGPKGDPGSLGP--- 491
            RG+PGP GP+G KG M                     G +GP G +GPKG  GS GP   
Sbjct: 875  RGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGL 934

Query: 492  LGPQGPQGQPGEAGPVGERGP---------VGPRGF---PGLKGSKGSFGTGGPRGQPGP 539
            LG QG QG  GE G  G+RGP          G RGF   PGL+G  GS G  G  G+PG 
Sbjct: 935  LGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGL 994

Query: 540  K---GDIGPPGP---EGPPGSPGPSGPQGKPGI---------AGKTGSPGQRGAMGPKGE 584
            +   GD+GPPG    EGPPG+ G SG QG+PG           G TG PG RG  G  GE
Sbjct: 995  RGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGE 1054

Query: 585  PGIQGPPGLPGPPGPPG 601
             G+QG  GL G PG  G
Sbjct: 1055 EGLQGKDGLKGVPGGRG 1071



 Score =  132 bits (332), Expect = 9e-31
 Identities = 75/168 (44%), Positives = 91/168 (54%), Gaps = 21/168 (12%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGP---------------KGDPGSLGPLGPQGPQGQP 501
           G PGP G +G  GD G  G +G  GP               KG+ GS GPLGPQG +G  
Sbjct: 831 GEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVM 890

Query: 502 GEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQ---PGPKGDIGPPGPEGPPGSPGPS 558
           G  GP G  GP+GP G PG  G++G  G+ GP+GQ    GP G +G  G +G  G  G  
Sbjct: 891 GYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQ 950

Query: 559 GPQGKPGIAGKTGSPGQRGAMGP---KGEPGIQGPPGLPGPPGPPGSQ 603
           G +G  G+ GKTG+PG+RG  G    +G PG  G  GLPG PG  G Q
Sbjct: 951 GKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQ 998



 Score =  132 bits (331), Expect = 1e-30
 Identities = 78/171 (45%), Positives = 85/171 (49%), Gaps = 22/171 (12%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRG------PKGDPGSLGPLGPQGPQGQPGEAGPVG 508
            LRG PG PG  G +G  G+KG  GGRG       KG+ G  G +GP G  GQ G  GP G
Sbjct: 1045 LRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEG 1104

Query: 509  ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS---------PGPSG 559
              G  G RG PG KG KG  G  G  G  GP G IG  GP+G  G+          GP G
Sbjct: 1105 IVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDG 1164

Query: 560  PQGKPGIAGKTGSPGQRGAMGPKGEPG-------IQGPPGLPGPPGPPGSQ 603
              G PG  G  G PG  G  GPKGE G       + GPPG  G PGP G Q
Sbjct: 1165 EPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQ 1215



 Score =  132 bits (331), Expect = 1e-30
 Identities = 72/160 (45%), Positives = 86/160 (53%), Gaps = 12/160 (7%)

Query: 456  RGAPGP---------PGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP 506
            RG PGP         PG  G+KG +GV G  G  G +G PG  G  G QG +G+ G  G 
Sbjct: 1206 RGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGN 1265

Query: 507  VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS---PGPSGPQGK 563
             G++G  GP G PG+ G +G  G  G +G  G  G  G PG  GPPG    PG  G  G+
Sbjct: 1266 KGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGR 1325

Query: 564  PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
             G+AG  G PG +G+ G  G PGIQGP G  G PG PG Q
Sbjct: 1326 TGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQ 1365



 Score =  130 bits (327), Expect = 3e-30
 Identities = 75/168 (44%), Positives = 91/168 (54%), Gaps = 21/168 (12%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQG------PQGQPGEAGPVGER 510
            G  G  GP G  G++G+ G +G +G +G PG LGP G +G      P G PG  GP+G  
Sbjct: 849  GKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLP 908

Query: 511  GPVGPRGFPGLKGSKGSFGTGGP---------RGQPGPKGDIGPPGPEG---PPGSPGPS 558
            G VG RG PG +G KG  G+ GP         +G  G KGD G  GP G     G+PG  
Sbjct: 909  GHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGER 968

Query: 559  GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQ---GPPGLPGPPGPPGSQ 603
            G QGKPG+ G  GS G RG  G  G  G+Q   GPPG  G  GPPG++
Sbjct: 969  GFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTE 1016



 Score =  130 bits (326), Expect = 5e-30
 Identities = 76/170 (44%), Positives = 88/170 (51%), Gaps = 15/170 (8%)

Query: 447 EILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQP----- 501
           E LR      G PGPPGP G  G  G +GP G  GP G+PG  G  GP+GP+G P     
Sbjct: 485 EYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPG 544

Query: 502 -------GEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGS 554
                  G+ G  G  GP G +G  GLKG  G  G  G +G PG  G+IG PG  G  G 
Sbjct: 545 QPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGL 604

Query: 555 PGPSGPQGKPGIAGKTGSPGQRGAMGPKGE---PGIQGPPGLPGPPGPPG 601
            GP G  G  G  G  GSPG+ G +GP+GE   PGI+G  G  G  G PG
Sbjct: 605 AGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPG 654



 Score =  129 bits (324), Expect = 8e-30
 Identities = 77/178 (43%), Positives = 89/178 (50%), Gaps = 31/178 (17%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP----LGPQGPQGQPGEAGPVGER 510
            L G  G PG  G++G  G  GP G  GPKG+ G  G     LGP GP+G+PG  G  GER
Sbjct: 1159 LMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGER 1218

Query: 511  GPVGPRGF------------------PGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP 552
            G  G  G+                  PG  G +G  G  G RG  G KG  G PGP G P
Sbjct: 1219 GEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKP 1278

Query: 553  GSP------GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPP---GLPGPPGPPG 601
            G P      GP G QG  G  G +G+PG+ G  G +G PGI+G P   GL G PGPPG
Sbjct: 1279 GIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPG 1336



 Score =  129 bits (324), Expect = 8e-30
 Identities = 73/177 (41%), Positives = 88/177 (49%), Gaps = 24/177 (13%)

Query: 449  LRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGS------------LGPLGPQG 496
            LR  T  +G PG PG +G +G  G +G  G +G KG PG             LGP G QG
Sbjct: 1235 LRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQG 1294

Query: 497  PQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPG 556
              G  G +G  G+ GP G +G PG++G  G  G  G  G PG KG  G PG  G  G  G
Sbjct: 1295 YHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKG 1354

Query: 557  PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPP------------GLPGPPGPPG 601
              G  G+PGI GK G  G +G  GP G+PG++G P            G PGP GP G
Sbjct: 1355 EQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEG 1411



 Score =  129 bits (323), Expect = 1e-29
 Identities = 72/153 (47%), Positives = 81/153 (52%), Gaps = 9/153 (5%)

Query: 453  TILRGAPGPPGPRG---FKGDMGVKGPVGGRGPKGDPG------SLGPLGPQGPQGQPGE 503
            T L GAPGPPG +G     G  G++GP G +G  G PG        G  G QGP G PG 
Sbjct: 1326 TGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGL 1385

Query: 504  AGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGK 563
             G  GE G  G  GF G  G KG  G  G  G  GPKG IG  G  GP G  G  GP G+
Sbjct: 1386 KGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGR 1445

Query: 564  PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGP 596
             G  G+ G  G+ G  GP+G+PG  GPPG PGP
Sbjct: 1446 TGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGP 1478



 Score =  128 bits (322), Expect = 1e-29
 Identities = 74/154 (48%), Positives = 82/154 (53%), Gaps = 9/154 (5%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G  GP GP G  G MG+ G  G  G KGD G  G  G  G  G PG+ G VG  GP G R
Sbjct: 687 GPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMR 746

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKG---DIGPP---GPEGPPGSPGPSGPQGKPGIAGKT 570
           G  G  G  G  G  GP G PGP+G   DIG P   GPEGP G  G  GP G PG+ G  
Sbjct: 747 GKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQ 806

Query: 571 GSPGQRGA---MGPKGEPGIQGPPGLPGPPGPPG 601
           G  G  GA   +GP+G+PG +G  G PGP G  G
Sbjct: 807 GEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKG 840



 Score =  128 bits (322), Expect = 1e-29
 Identities = 71/154 (46%), Positives = 82/154 (53%), Gaps = 7/154 (4%)

Query: 457  GAPGPPGPRGFKGDMG---VKGPVGGRGPKGDPGSLGP---LGPQGPQGQPGEAGPVGER 510
            G PGP G  G  G  G    KG  G  GP G+ GS GP   +G  GP+G  G  G VG  
Sbjct: 1098 GLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHL 1157

Query: 511  GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPP-GSPGPSGPQGKPGIAGK 569
            G +GP G PG+ G +G  G  GP G PGPKG+ G PG +    G PGP G  G  G  G+
Sbjct: 1158 GLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGE 1217

Query: 570  TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
             G PG  G  G  G PG++G  G  GPPG PG Q
Sbjct: 1218 RGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQ 1251



 Score =  128 bits (322), Expect = 1e-29
 Identities = 73/156 (46%), Positives = 84/156 (53%), Gaps = 12/156 (7%)

Query: 460  GPPGPRGFKG---DMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            GPPGPRG  G   D G +G  G  G KG  G  G  G  G QG PGE G  GE+G  G R
Sbjct: 1201 GPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGER 1260

Query: 517  GFPGLKGSKGSFGTGGPRGQPGPKGDIGPP------GPEGPPGSPGPSGPQGKPGIAGKT 570
            G  G KG KG+ G  G  G PG +G +GP       G +G  G+PG  GP GK G+ G  
Sbjct: 1261 GSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIR 1320

Query: 571  GSPGQRGAMGPKGEPGIQGPPGLPGPP---GPPGSQ 603
            G PG+ G  G  G PG++G  GLPG P   GP G Q
Sbjct: 1321 GGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQ 1356



 Score =  127 bits (318), Expect = 4e-29
 Identities = 72/163 (44%), Positives = 84/163 (51%), Gaps = 15/163 (9%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            RG PG PG RG +GD+G  G +G  GP G  G  G  G  G +G  G AG VG  G  G 
Sbjct: 986  RGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGL 1045

Query: 516  RGFPG------LKGSKGSFGTGGPRGQPGPKGD---------IGPPGPEGPPGSPGPSGP 560
            RG PG      L+G  G  G  G RG PG  G+         IGP G  G  G PGP G 
Sbjct: 1046 RGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGI 1105

Query: 561  QGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
             G PG  G+ G  G +G +GP GE G +GPPG  G  GP G++
Sbjct: 1106 VGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGAR 1148



 Score =  122 bits (305), Expect = 1e-27
 Identities = 71/164 (43%), Positives = 85/164 (51%), Gaps = 19/164 (11%)

Query: 457  GAPGPPG------PRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGER 510
            G+ GPPG      P+G +G  G  G +G  GP G+PG  G  G QG  G  G  GP GE+
Sbjct: 1131 GSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEK 1190

Query: 511  G----------PVGPRGFPGL---KGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP 557
            G          P GPRG PG    +G +G  G  G +G  G  G  G  G +GPPG PG 
Sbjct: 1191 GYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGD 1250

Query: 558  SGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
             G QG  G  G  G+ G++GA GP G+PGI G  GL GP G  G
Sbjct: 1251 QGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQG 1294



 Score =  121 bits (303), Expect = 2e-27
 Identities = 70/154 (45%), Positives = 83/154 (53%), Gaps = 9/154 (5%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PG PGP+G KGD G        G KGD G  G +GP G QG  G  G  G  G  G +
Sbjct: 525 GLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQ 584

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP------GPSGPQGKPGIAGKT 570
           G PG  G+ GS G  G +G  GP+G+ GP G +G  GSP      GP G +G PGI GK 
Sbjct: 585 GIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKK 644

Query: 571 GSPGQR---GAMGPKGEPGIQGPPGLPGPPGPPG 601
           G  G++   G  G +G  G+ G PGL G  GPPG
Sbjct: 645 GFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPG 678



 Score =  120 bits (300), Expect = 5e-27
 Identities = 67/159 (42%), Positives = 80/159 (50%), Gaps = 12/159 (7%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
           L G  G PG +G KG+ G  G +G  G  GD G++G  GP G +G+ G +G  G+ G  G
Sbjct: 703 LSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQG 762

Query: 515 PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS------------GPQG 562
           P G PG +G  G  G  G  G  GPKG +G  GP GPPG  G              GP+G
Sbjct: 763 PSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRG 822

Query: 563 KPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           KPG  G  G PG  G  G  G+ G  G  G  GP G PG
Sbjct: 823 KPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPG 861



 Score =  115 bits (288), Expect = 1e-25
 Identities = 71/175 (40%), Positives = 86/175 (49%), Gaps = 27/175 (15%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGP---------------KGDPGSLGPLGPQGPQGQ 500
            RG  G  G +G +G  G KG  G RGP               +G PG  G  G  G +G 
Sbjct: 929  RGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGL 988

Query: 501  PGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDI---------GPPGPEGP 551
            PGE G  G +G VGP G  G++G  G+ G  G +G+PG KGD+         G PG  G 
Sbjct: 989  PGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGE 1048

Query: 552  PGSPGPSGPQGKPGIAGKTGS---PGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            PG+PG  G QGK G+ G  G    PG+ G  G  G PGI GP G  G  G PG +
Sbjct: 1049 PGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPE 1103



 Score =  111 bits (278), Expect = 2e-24
 Identities = 66/132 (50%), Positives = 72/132 (54%), Gaps = 6/132 (4%)

Query: 480 RGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGG-PRGQ-- 536
           RGPKGD G  GP GP G  G  G+ GP G  GP G  G PGL G KG  G  G   GQ  
Sbjct: 488 RGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPV 547

Query: 537 PGPKGDIGPPGPEGPPGSPGPSGPQGK---PGIAGKTGSPGQRGAMGPKGEPGIQGPPGL 593
           PG KGD G  G  GPPG  G  G +G    PG+ G+ G PG  G +G  G PG QG  G 
Sbjct: 548 PGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGP 607

Query: 594 PGPPGPPGSQSF 605
            G PGP G+Q F
Sbjct: 608 EGNPGPKGAQGF 619



 Score =  105 bits (262), Expect = 1e-22
 Identities = 58/125 (46%), Positives = 67/125 (53%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            L G PG  G RG +G  G +GP G  G KG PG  G  G  G QG PG  GP G+ G VG
Sbjct: 1358 LPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVG 1417

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574
              G  G  G +G+ G  G  G  GP G  GP G +G  G  GP GP+G+PG  G  G+PG
Sbjct: 1418 ISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPG 1477

Query: 575  QRGAM 579
             R  M
Sbjct: 1478 PRKQM 1482



 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 47/106 (44%), Positives = 57/106 (53%), Gaps = 16/106 (15%)

Query: 444  QHGEI-LRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG 502
            Q GE  ++ +T  +G PGP GP G  G +G+ GP   +GP G  G+ GPLG +G  G  G
Sbjct: 1388 QPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGP---KGPIGHRGNTGPLGREGIIGPTG 1444

Query: 503  EAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGP 548
              GP GE            KG +G  G  GPRGQPGP G  G PGP
Sbjct: 1445 RTGPRGE------------KGFRGETGPQGPRGQPGPPGPPGAPGP 1478


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score =  152 bits (384), Expect = 9e-37
 Identities = 81/151 (53%), Positives = 89/151 (58%), Gaps = 6/151 (3%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           +G PG PGPRG  G  G KG  G  G  G+PG  G +G QGPQG+ GEAGP G  G V  
Sbjct: 277 KGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIG 336

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
            G  G KG +G  GT GPRG+PGPKG  G PG  GPPG P P G  G PG  G+ G  G 
Sbjct: 337 TGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVP-GQAGAPGFPGERGEKGD 395

Query: 576 RG-----AMGPKGEPGIQGPPGLPGPPGPPG 601
           RG       GP G  G+ GPPG PGPPG PG
Sbjct: 396 RGFPGTSLPGPSGRDGLPGPPGSPGPPGQPG 426



 Score =  142 bits (357), Expect = 1e-33
 Identities = 75/157 (47%), Positives = 82/157 (52%), Gaps = 10/157 (6%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PG  GP G +G  G KG  G  G  G  G+ GP G  G  G PG  G  G+ GP GP 
Sbjct: 61  GFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPP 120

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP----------SGPQGKPGI 566
           G PG  G+KG  G  GP G PG  G+ GPPG  G  G PG            G +G PGI
Sbjct: 121 GIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGI 180

Query: 567 AGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            G  G PG  G  GP G PG  GPPG PGPPGPPG +
Sbjct: 181 PGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEK 217



 Score =  142 bits (357), Expect = 1e-33
 Identities = 81/174 (46%), Positives = 91/174 (52%), Gaps = 27/174 (15%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSL--GPLGPQGPQGQPGEAGPVGERGP 512
            L G+PG PG +G +G MG  GP G  G  G PG    GP G +GPQGQPG  G  G  GP
Sbjct: 1196 LAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGP 1255

Query: 513  VGPRGFPGLKGSKGSFGTGGPRGQPGPKGD---------------IGPPGPEGPPGSPGP 557
             G  G  G+KG KG+ G  G  G PGPKGD                G  G  GPPG PG 
Sbjct: 1256 PGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGF 1315

Query: 558  SGPQGKPGIAGKTGSPGQRGAMGPKGEPG----------IQGPPGLPGPPGPPG 601
             GP+G PG+ G  G  G +G  G KG PG          I+G PGLPGP GPPG
Sbjct: 1316 QGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPG 1369



 Score =  139 bits (351), Expect = 6e-33
 Identities = 78/163 (47%), Positives = 82/163 (50%), Gaps = 9/163 (5%)

Query: 449  LRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG 508
            L  +T   G PG PG +G  G  G  G  G  G  G PG  G  GP G  G PGE G  G
Sbjct: 850  LPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHG 909

Query: 509  ERGPVGPRGFPGLKGSKGSFGTGGPRGQ---------PGPKGDIGPPGPEGPPGSPGPSG 559
              G  GPRG PGLKG KG  G  G  G           G KGD G  G  GP G  G  G
Sbjct: 910  FPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRG 969

Query: 560  PQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
              G PG+ GK G  GQ G  GPKG+PGI G PG PG PGP GS
Sbjct: 970  DPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGS 1012



 Score =  139 bits (351), Expect = 6e-33
 Identities = 89/196 (45%), Positives = 98/196 (50%), Gaps = 46/196 (23%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG------------ 502
            L G PGP GP G  G  GVKG  G  G  G PG  GP G  G QG PG            
Sbjct: 1246 LPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKG 1305

Query: 503  EAGPVGERGPVGPRGFPGLKGSKG---------SFGTGGPRGQPGP----KGDIGPPGPE 549
            + GP G  G  GP+G PGL+G KG         + G  GP G PGP    KG+ G PGPE
Sbjct: 1306 DMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPE 1365

Query: 550  GPP------GSPGPSGPQ---------GKPGIAGKTGSPGQRGAM------GPKGEPGIQ 588
            GPP      G PGP G Q         G PGI G  G+PGQ+G M      GP+G PG  
Sbjct: 1366 GPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPP 1425

Query: 589  GPPGLPGPPGPPGSQS 604
            GP GLPG  GPPG+ S
Sbjct: 1426 GPDGLPGSMGPPGTPS 1441



 Score =  139 bits (349), Expect = 1e-32
 Identities = 75/155 (48%), Positives = 82/155 (52%), Gaps = 8/155 (5%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG--------EAGPVG 508
            G PG  G +G KG++G  G  G  G  G  G  G +GP GPQGQPG          GP G
Sbjct: 1177 GFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKG 1236

Query: 509  ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAG 568
            +RGP G  G PGL G  G  G  G  G  G KG+ G PG  G PG  G  G QG PGI G
Sbjct: 1237 DRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGG 1296

Query: 569  KTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
              G  G +G MGP G PG QGP GLPG  G  G Q
Sbjct: 1297 SPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQ 1331



 Score =  133 bits (335), Expect = 4e-31
 Identities = 84/196 (42%), Positives = 96/196 (48%), Gaps = 49/196 (25%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE---AGPVGERGPV 513
            G+PG PG +G KG  G+ G  G +G  G PG+ GP GP G +G+PG     G  GE+G  
Sbjct: 1109 GSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEP 1168

Query: 514  G--PRGFPGL------KGSKGS---------------------FGTGGPRGQP------- 537
            G   RGFPG       KGSKG                       G  GP+GQP       
Sbjct: 1169 GLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPG 1228

Query: 538  ----GPKGDIGPPGPEGPPGSPGPSGPQGKPGI------AGKTGSPGQRGAMGPKGEPGI 587
                GPKGD GP G  G PG PGP GP G PGI       G  G PG  G  GPKG+PG 
Sbjct: 1229 HATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGF 1288

Query: 588  QGPPGLPGPPGPPGSQ 603
            QG PG+ G PG  GS+
Sbjct: 1289 QGMPGIGGSPGITGSK 1304



 Score =  133 bits (334), Expect = 5e-31
 Identities = 78/178 (43%), Positives = 89/178 (50%), Gaps = 29/178 (16%)

Query: 457  GAPGPPGP---------RGFKGDMGVKG---PVGGRGPKGDPGSLGPLGPQGPQGQPGEA 504
            G PG PG          +G KGD G KG   P+G +G +GDPG+ G  G  G  GQPG+ 
Sbjct: 930  GLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQP 989

Query: 505  GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564
            GP G+ G  G  G PGL G KGS G  G  G PG KG  G PGP+G PG PG  G +G+ 
Sbjct: 990  GPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEK 1049

Query: 565  GIAGK-----------------TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
            G AG                   G PG  G  G KG  GI G PG PG  G PGS  +
Sbjct: 1050 GQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGY 1107



 Score =  132 bits (332), Expect = 9e-31
 Identities = 78/169 (46%), Positives = 87/169 (51%), Gaps = 24/169 (14%)

Query: 457 GAPGPPGPRGFKGDMGV--------KGPVGGRGPKGDPGSL-----GPLGPQGPQGQPGE 503
           G PGPPGP G KG MG+        KG  G  GP G PG       G    +G +GQ GE
Sbjct: 206 GPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGE 265

Query: 504 --------AGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP 555
                    G  GE G  GPRG PG  G KG  G+ G  G+PG  G IG  GP+G  G  
Sbjct: 266 PGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEA 325

Query: 556 GPSGPQG---KPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           GP GP G     G  G+ G  G  G  GP+GEPG +G PGLPG PGPPG
Sbjct: 326 GPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPG 374



 Score =  129 bits (325), Expect = 6e-30
 Identities = 76/176 (43%), Positives = 86/176 (48%), Gaps = 31/176 (17%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP---- 512
           G  GPPGP G  G  G KG  G  GP G PG  G  GP G  G  G+ G +    P    
Sbjct: 112 GQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLL 171

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP-----------GPSGPQ 561
            G RGFPG+ G+ G  G  G +G  GP G  GPPGP GPPG P           GP G +
Sbjct: 172 KGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDK 231

Query: 562 GKPGIAGKTGSPGQ-----------RGAMGPKGEPGIQGPPGL-----PGPPGPPG 601
           G  G++G  G PGQ           +G  G KGEPG QG PG+     PG PGP G
Sbjct: 232 GDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRG 287



 Score =  129 bits (324), Expect = 8e-30
 Identities = 87/202 (43%), Positives = 102/202 (50%), Gaps = 42/202 (20%)

Query: 444 QHGE--ILRNVTILRGAPGPPGPR---GFKGDMGVKGPVG--GR-------GPKGDPGSL 489
           Q GE  ++ ++   RG PGP GP    GF G  G KG  G  GR       GP+G PG +
Sbjct: 462 QKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLI 521

Query: 490 GPLGPQGPQGQ----------------PGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGP 533
           G  G +G  G+                PG+ G  G  G  G  G PGL G KGS G+ G 
Sbjct: 522 GQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGL 581

Query: 534 RGQPGPKGDIGPPGPE---GPPGSP--GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPG-- 586
           +G+ GP G +G PG     GPPG P  GP+GP G  G AG  G PG  G  GPKGEPG  
Sbjct: 582 KGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKI 641

Query: 587 --IQGPP---GLPGPPGPPGSQ 603
             + GPP   GLPG PG PG Q
Sbjct: 642 VPLPGPPGAEGLPGSPGFPGPQ 663



 Score =  129 bits (324), Expect = 8e-30
 Identities = 75/152 (49%), Positives = 82/152 (53%), Gaps = 5/152 (3%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PG PG  G  G  G++G  G  GP G PGS+G  G  G  G PG  GP G +GP G  
Sbjct: 761 GVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGI-GPPGARGPPGGQGPPGLS 819

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGDIGP---PGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
           G PG+KG KG  G  G    PGPKGD G    PG  G  G PG  G QG PGI G  GS 
Sbjct: 820 GPPGIKGEKGFPGFPG-LDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSK 878

Query: 574 GQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
           G+ G MG  G+PG  GP G PG PG  G   F
Sbjct: 879 GEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGF 910



 Score =  129 bits (323), Expect = 1e-29
 Identities = 80/175 (45%), Positives = 88/175 (50%), Gaps = 29/175 (16%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PG PG  G  G  G  G  G  GPKG PGS+G  G +GP   PG  G  G RG  GP 
Sbjct: 547 GFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGP---PGGVGFPGSRGDTGPP 603

Query: 517 GFPGL--------KGSKGSFGTGGPRGQPGPKGD-------IGPPGPEGPPGSPGPSGPQ 561
           G PG         KG  G  G  G  G PGPKG+        GPPG EG PGSPG  GPQ
Sbjct: 604 GPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQ 663

Query: 562 GK---PGIAGKTGSPGQRGAM--------GPKGEPGIQGPPGLPGPPGPPGSQSF 605
           G    PG  G+ G PG++GA+        GP G  G+ G PG  GPPG PG   F
Sbjct: 664 GDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGF 718



 Score =  128 bits (322), Expect = 1e-29
 Identities = 80/189 (42%), Positives = 96/189 (50%), Gaps = 29/189 (15%)

Query: 446 GEILRNVTIL-----RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQ 500
           GEIL +V  +     RG PG PG  G  G  G++GPVG  G  G PG  GP GP G +GQ
Sbjct: 160 GEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQ 219

Query: 501 PGEA--GPVGERGPVGPRGFPGLKG-----SKGSFGTGGPRGQP-----------GPKGD 542
            G +  GP G++G  G  G PG+ G      KG F T G +GQ            G KG+
Sbjct: 220 MGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGE 279

Query: 543 IGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP------GP 596
            G PGP G PG  G  G +G PG  G+ G PG  G  GP+GE G  GPPG P      GP
Sbjct: 280 PGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGP 339

Query: 597 PGPPGSQSF 605
            G  G + +
Sbjct: 340 LGEKGERGY 348



 Score =  128 bits (322), Expect = 1e-29
 Identities = 70/170 (41%), Positives = 88/170 (51%), Gaps = 23/170 (13%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGG------------RGPKGDPGSLGPLGPQGPQGQPGEA 504
            G  G PG +G KGD+G+ G  G             +G +G+ G +GP+G +G +G PG  
Sbjct: 915  GPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTP 974

Query: 505  GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGP---PGPEGPPGSPGPSGPQ 561
            G  G+ G  G  G PG KG  G  GT G  G PGPKG +G    PG  G  G PG  GPQ
Sbjct: 975  GVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQ 1034

Query: 562  GKPGIAGKTGSPGQRGAMGP--------KGEPGIQGPPGLPGPPGPPGSQ 603
            G PG+ G  G+ G++G  GP        +GE G QG  G PG PG  G +
Sbjct: 1035 GSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEK 1084



 Score =  128 bits (322), Expect = 1e-29
 Identities = 73/150 (48%), Positives = 83/150 (55%), Gaps = 11/150 (7%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            GAPG PGP+G  G MG+ G  G    KG PG     GPQG  G PG+ G  GE+G  GP 
Sbjct: 1002 GAPGLPGPKGSVGGMGLPGTPG---EKGVPGI---PGPQGSPGLPGDKGAKGEKGQAGPP 1055

Query: 517  --GFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574
              G PGL+G KG  G  G  G PG KG+ G  G  G PGSPG  G  G  G  G  G PG
Sbjct: 1056 GIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPG 1115

Query: 575  Q---RGAMGPKGEPGIQGPPGLPGPPGPPG 601
            +   +G  G  G PG++G  GLPG PGP G
Sbjct: 1116 EKGDKGLPGLDGIPGVKGEAGLPGTPGPTG 1145



 Score =  128 bits (321), Expect = 2e-29
 Identities = 76/161 (47%), Positives = 84/161 (52%), Gaps = 15/161 (9%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGD--PGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            G PGP G  G  GD G KG  G  GP G   PG  G  G QG  G PG  G  GE+G +G
Sbjct: 1029 GIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIG 1088

Query: 515  PRGFPG---LKGSKGSFGTGGPRGQPGPKGDIGPPGPE---------GPPGSPGPSGPQG 562
              G PG   LKGS GS G  G  G PG KGD G PG +         G PG+PGP+GP G
Sbjct: 1089 IPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAG 1148

Query: 563  KPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
            + G  G  G PG  G  G  G PG +G PG PG  G  GS+
Sbjct: 1149 QKGEPGSDGIPGSAGEKGEPGLPG-RGFPGFPGAKGDKGSK 1188



 Score =  127 bits (318), Expect = 4e-29
 Identities = 78/173 (45%), Positives = 89/173 (51%), Gaps = 29/173 (16%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVG--GR-------------GPKGDPGSLGPLGPQGPQGQP 501
           G PGPPGP+G  G  G  GP G  GR             G KG+PG +G  G +G  G P
Sbjct: 690 GFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPG-VGLPGLKGLPGLP 748

Query: 502 GEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKG-----------DIGPPGPEG 550
           G  G  GE+G +G  G PG  G+ G  G  G RG+PGP G            IGPPG  G
Sbjct: 749 GIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARG 808

Query: 551 PPGSPGPSGPQGKPGIAGKTGSPGQRG--AMGPKGEPGIQGPPGLPGPPGPPG 601
           PPG  GP G  G PGI G+ G PG  G    GPKG+ G QG PG+ G  G PG
Sbjct: 809 PPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPG 861



 Score =  127 bits (318), Expect = 4e-29
 Identities = 77/179 (43%), Positives = 86/179 (48%), Gaps = 32/179 (17%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG------------EA 504
            G+PGP G  G  G+ G  G  G  GP+GDPG  G  G  G  G+PG            + 
Sbjct: 891  GSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQK 950

Query: 505  GPVGERGPVGP------RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS 558
            G  GE+G +GP      RG PG  G  G  G  G  GQPGPKGD G  G  G PG PGP 
Sbjct: 951  GDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPK 1010

Query: 559  ------------GPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPP--GLPGPPGPPGSQ 603
                        G +G PGI G  GSPG  G  G KGE G  GPP  G+PG  G  G Q
Sbjct: 1011 GSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQ 1069



 Score =  125 bits (313), Expect = 1e-28
 Identities = 80/178 (44%), Positives = 89/178 (50%), Gaps = 27/178 (15%)

Query: 455 LRGAPGPPGP---RGFKGDMGVKGPVGGRGPKGDP--GSLGPLGPQGPQGQPGEAGPVGE 509
           L G+PG PGP   RGF G  G  G  G +G  G P  G  GP GP+G  G PG+ GP G 
Sbjct: 653 LPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGT 712

Query: 510 RGPVGPRGF---PGLKGSKGSFGTG-----------GPRGQPGPKGDIGPPGPE------ 549
            G  G  G    PG++G KG  G G           G  G PG KG IG PG        
Sbjct: 713 PGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAI 772

Query: 550 GPPGSPGPSGPQGKPGIAGKTGSPGQR--GAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
           GPPG  G  G  G PG+ G  GSPG    G  G +G PG QGPPGL GPPG  G + F
Sbjct: 773 GPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGF 830



 Score =  124 bits (312), Expect = 2e-28
 Identities = 76/167 (45%), Positives = 86/167 (51%), Gaps = 19/167 (11%)

Query: 455 LRGAPGPPGPRGFKG-DMGV----KGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV-- 507
           L G PG PGP G  G   G+     GP G +GP G PG  G +G  G +GQ GE+  +  
Sbjct: 412 LPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICD 471

Query: 508 --GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP- 564
             G RGP GP+G PG  G  G  G  G RG PG  G  G PGP+G PG  G  G +G+P 
Sbjct: 472 IDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPG 531

Query: 565 ---------GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
                    G  G  G PGQ G  G  G PG  G PGLPGP G PGS
Sbjct: 532 EFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGS 578



 Score =  124 bits (311), Expect = 3e-28
 Identities = 83/195 (42%), Positives = 96/195 (49%), Gaps = 52/195 (26%)

Query: 457 GAPGPPG--PRGFKGDMGVKGPVGGRG------PKGDPGSL----GPLGPQGPQGQPGEA 504
           G PGPPG  P G  GD G  G  GG G      PKG+PG +    GP G +G  G PG  
Sbjct: 601 GPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFP 660

Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPR--GQPGPKG------DIGPPGPEGPPG--- 553
           GP G+RG  G  G PGL G KG+ G  G    G PGPKG      D+GPPG  G PG   
Sbjct: 661 GPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNG 720

Query: 554 ---SPGPSGPQGKPGIA-----------------------GKTGSPGQRGAMGPKGEPGI 587
              +PG  G +G+PG+                        G  G PG+ GA+GP   PG+
Sbjct: 721 LPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGP---PGL 777

Query: 588 QGPPGLPGPPGPPGS 602
           QG  G PGPPG PGS
Sbjct: 778 QGIRGEPGPPGLPGS 792



 Score =  123 bits (309), Expect = 4e-28
 Identities = 71/158 (44%), Positives = 86/158 (54%), Gaps = 10/158 (6%)

Query: 455 LRGAPGPPGPRGFKGDMGVKG--PVGGRGP---KGDPGSLGPLGPQGPQGQPGEAG--PV 507
           +RG PGPPG  G  G  GV G  P G RGP   +G PG  GP G +G +G PG  G    
Sbjct: 780 IRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMP 839

Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKG---DIGPPGPEGPPGSPGPSGPQGKP 564
           G +G  G +G PG+ G  G  G  G +G PG  G     G  G  G PG PG  GP G P
Sbjct: 840 GPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAP 899

Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           G+ G+ G  G  G+ GP+G+PG++G  G  G PG PGS
Sbjct: 900 GLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGS 937



 Score =  123 bits (309), Expect = 4e-28
 Identities = 73/180 (40%), Positives = 87/180 (48%), Gaps = 35/180 (19%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPG-----SLGPLGPQGPQGQPGEAGPVG--- 508
           G PG  GP G +G  G+ GP G +G KG PG       GP G +G QG PG  G  G   
Sbjct: 802 GPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPG 861

Query: 509 ---ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPG 565
              ++G  G  GFPG KG  G  GT G  G PGP G  G PG +G  G PG SGP+G PG
Sbjct: 862 LPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPG 921

Query: 566 IAG------------------------KTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           + G                        + G  G++G +GP GE G +G PG PG PG  G
Sbjct: 922 LKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDG 981



 Score =  122 bits (307), Expect = 7e-28
 Identities = 67/146 (45%), Positives = 78/146 (53%), Gaps = 4/146 (2%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
            +G+ G PG  G  G  G  G  G  GPKGDPG  G  G  G  G  G  G +G  G  G 
Sbjct: 965  KGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGE 1024

Query: 516  RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
            +G PG+ G +GS G  G +G  G KG  GPPG     G PG  G +G  GIAG  GSPG+
Sbjct: 1025 KGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPG----IGIPGLRGEKGDQGIAGFPGSPGE 1080

Query: 576  RGAMGPKGEPGIQGPPGLPGPPGPPG 601
            +G  G  G PG+ G PGL G PG  G
Sbjct: 1081 KGEKGSIGIPGMPGSPGLKGSPGSVG 1106



 Score =  121 bits (303), Expect = 2e-27
 Identities = 69/151 (45%), Positives = 80/151 (52%), Gaps = 10/151 (6%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG 514
            + G PG PG +G KG +G+ G  G  G KG PGS+G        G PG  G  G++G  G
Sbjct: 1071 IAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGY------PGSPGLPGEKGDKGLPG 1124

Query: 515  PRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574
              G PG+KG  G  GT GP G  G KG+   PG +G PGS G  G  G PG  G  G PG
Sbjct: 1125 LDGIPGVKGEAGLPGTPGPTGPAGQKGE---PGSDGIPGSAGEKGEPGLPG-RGFPGFPG 1180

Query: 575  QRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
             +G  G KGE G  G  G PG PG  G Q F
Sbjct: 1181 AKGDKGSKGEVGFPGLAGSPGIPGSKGEQGF 1211



 Score =  119 bits (297), Expect = 1e-26
 Identities = 80/202 (39%), Positives = 88/202 (43%), Gaps = 55/202 (27%)

Query: 457 GAPGPPG------PRGFKGDMG---VKGPVGGRGPKGDPGSLGPLGPQG--PQGQPGEAG 505
           G PGPPG      P G KG+ G     GP G  GPKG PG  G  GP G    GQ G  G
Sbjct: 326 GPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPG 385

Query: 506 PVGERGPVGPRGFPG--LKGSKGSFGTGGPRGQPGPKGDIG-----------PPGPEGPP 552
             GERG  G RGFPG  L G  G  G  GP G PGP G  G           PPG +GPP
Sbjct: 386 FPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPP 445

Query: 553 G-------------------------------SPGPSGPQGKPGIAGKTGSPGQRGAMGP 581
           G                                PGP GP G+ G  G+ G+ G RG  G 
Sbjct: 446 GIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGR 505

Query: 582 KGEPGIQGPPGLPGPPGPPGSQ 603
            G  G+ GP G PG  G PG++
Sbjct: 506 DGVAGVPGPQGTPGLIGQPGAK 527



 Score =  118 bits (296), Expect = 1e-26
 Identities = 82/212 (38%), Positives = 91/212 (42%), Gaps = 70/212 (33%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVG---GRGPKGDPGSLGPLGPQGPQGQPGEAG-------- 505
           G  G  GP+G KG+ G  GP G   G GP G+ G  G  G  GP+G+PG  G        
Sbjct: 311 GLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQP 370

Query: 506 -----PV----------GERGPVGPRGFPG--LKGSKGSFGTGGPRGQPGPKG------- 541
                PV          GERG  G RGFPG  L G  G  G  GP G PGP G       
Sbjct: 371 GPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNG 430

Query: 542 ----DIGPPGPEGPPGSP----------------------------GPSGPQGKPGIAGK 569
                 GPPG +GPPG P                            GP GPQG P   G+
Sbjct: 431 IVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPP---GE 487

Query: 570 TGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            G PGQ GA G +G PG  G  G+PGP G PG
Sbjct: 488 IGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPG 519



 Score =  118 bits (296), Expect = 1e-26
 Identities = 73/171 (42%), Positives = 87/171 (50%), Gaps = 26/171 (15%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDP-------GSLGPLGPQGPQGQ---PGEAGP 506
           G PG  GP G  G  G  G +G +G KG+        G  GP GPQGP G+   PG+ G 
Sbjct: 437 GPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGA 496

Query: 507 VGERGPVGP---RGFPGLKGSKGSFGTGGPRGQPGP-------KGDIGPPGPEGPPGSPG 556
            G+RG  G     G PG +G+ G  G  G +G+PG        KGD G PG  G PG  G
Sbjct: 497 KGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTG 556

Query: 557 PSGPQGK---PGIAGKTGSPGQRGAMGPKGEPGIQGPPGL---PGPPGPPG 601
            +G  G+   PG+ G  GSPG  G  G +G PG  G PG     GPPGPPG
Sbjct: 557 RAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPG 607



 Score =  118 bits (295), Expect = 2e-26
 Identities = 69/156 (44%), Positives = 79/156 (50%), Gaps = 16/156 (10%)

Query: 459 PGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGP-----------V 507
           PGPPG  G  G  G  GP G RG  G PG  G  G +G  GQPG   P            
Sbjct: 645 PGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLP 704

Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGP--KGDIGPPGPEGPPGSPGPSGPQGKPG 565
           G+ GP G  G PG  G  G+ G  G +G+PG    G  G PG  G PG+PG  G  G PG
Sbjct: 705 GDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPG 764

Query: 566 IAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           + G+ G+ G  G  G +GEP   GPPGLPG  G PG
Sbjct: 765 VPGEHGAIGPPGLQGIRGEP---GPPGLPGSVGSPG 797



 Score =  116 bits (290), Expect = 7e-26
 Identities = 67/157 (42%), Positives = 74/157 (47%), Gaps = 22/157 (14%)

Query: 469 GDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSF 528
           G     G  G +G +G PG  G +G  G QG  G  GP G++G  G  G PG KG++G  
Sbjct: 37  GKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPP 96

Query: 529 GTGGPRGQPGPKGDIGPPGPEGPPGSP---------GPSGPQGKPGIAGKTGSPGQRGAM 579
           G  G  G PG  G  G  GP GPPG P         GP GP G PG AG  G PG  G  
Sbjct: 97  GASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMK 156

Query: 580 GP-------------KGEPGIQGPPGLPGPPGPPGSQ 603
           G              KGE G  G PG PGPPG PG Q
Sbjct: 157 GDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQ 193



 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 53/119 (44%), Positives = 63/119 (52%), Gaps = 7/119 (5%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGP----KGDPGSLGPLGPQGPQGQPGEAGPVGER 510
            L+G  G  G +G  G  G+ GP G  GP    KG+PG  GP GP G +G  G  GP G++
Sbjct: 1324 LQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQ 1383

Query: 511  GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGP---PGPEGPPGSPGPSGPQGKPGI 566
            G  G  G PG  G  G  G  G +G+ GP G  GP   PGP GP G PG  GP G P +
Sbjct: 1384 GVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSV 1442



 Score = 95.9 bits (237), Expect = 1e-19
 Identities = 52/110 (47%), Positives = 60/110 (54%), Gaps = 9/110 (8%)

Query: 496 GPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP 555
           G +GQ GE G  G +G +G   FPG++G +G      P+G PG KGD G PG  G  G+ 
Sbjct: 43  GVKGQKGERGLPGLQGVIG---FPGMQGPEG------PQGPPGQKGDTGEPGLPGTKGTR 93

Query: 556 GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
           GP G  G PG  G  G PGQ G  GP G PG  G  G  GP GPPG   F
Sbjct: 94  GPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGF 143



 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 46/102 (45%), Positives = 55/102 (53%), Gaps = 15/102 (14%)

Query: 454  ILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPV 513
            I++G PG PGP   +G  G+KG  G  GPKG  G  G +G  GP G PG  G  G++G +
Sbjct: 1354 IIKGEPGLPGP---EGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEM 1410

Query: 514  GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSP 555
            GP             G  GPRG PGP G  G PG  GPPG+P
Sbjct: 1411 GPA------------GPTGPRGFPGPPGPDGLPGSMGPPGTP 1440



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 32/72 (44%), Positives = 37/72 (51%), Gaps = 12/72 (16%)

Query: 450  RNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE 509
            + VT L G PGPPG  GF G  G K            G +GP GP GP+G PG  GP G 
Sbjct: 1383 QGVTGLVGIPGPPGIPGFDGAPGQK------------GEMGPAGPTGPRGFPGPPGPDGL 1430

Query: 510  RGPVGPRGFPGL 521
             G +GP G P +
Sbjct: 1431 PGSMGPPGTPSV 1442


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  151 bits (381), Expect = 2e-36
 Identities = 81/158 (51%), Positives = 92/158 (58%), Gaps = 11/158 (6%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPL--------GPQGPQGQPGEAGP 506
            L G PG PG  G KG+ G  G  G +GP G PGS GP         GPQGP G+PG  G 
Sbjct: 1209 LPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGF 1268

Query: 507  VGERGPVGPRGFPG---LKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGK 563
             G  GP GP G PG   +KG KG+ G  G  G PG KGD GPPG +G PG PG +G +G 
Sbjct: 1269 QGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGD 1328

Query: 564  PGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            PG+ G  G PG +G  G  G  G +G PGL GPPGPPG
Sbjct: 1329 PGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPG 1366



 Score =  146 bits (368), Expect = 6e-35
 Identities = 85/189 (44%), Positives = 97/189 (51%), Gaps = 40/189 (21%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLG------PLGPQGPQGQPGEAGP-- 506
           L G PGPPG  GFKG +G KG  G  GP G PG  G      P G  GP GQPG  GP  
Sbjct: 755 LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPG 814

Query: 507 ---VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKG-DI-GPPGPEGPPG---SPGPS 558
              +G +GP GP G PG  G  G  G  G +G PGP G D+ GPPG  G PG   +PGP 
Sbjct: 815 LPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPI 874

Query: 559 GPQGKPGIAGKTGS------------------------PGQRGAMGPKGEPGIQGPPGLP 594
           GP G PG+ GK G+                        PG+ G  G KG+ G+QG PGLP
Sbjct: 875 GPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLP 934

Query: 595 GPPGPPGSQ 603
           GP G  GS+
Sbjct: 935 GPTGEKGSK 943



 Score =  145 bits (367), Expect = 8e-35
 Identities = 80/168 (47%), Positives = 91/168 (54%), Gaps = 20/168 (11%)

Query: 455  LRGAPGP---PGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERG 511
            L G PGP   PG  G+ G+ G+KG VG  G  G PG+ G  G  G  G PG  GP G +G
Sbjct: 1075 LPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKG 1134

Query: 512  PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPS-----------GP 560
              GP G PGL G  G  G GG  GQPGP G+ G PG +G PG  G             GP
Sbjct: 1135 ISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGP 1194

Query: 561  QGKPGIAGKTGS------PGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
             G PG++G+ G       PG  G  GPKGEPG  G PG+ GPPGPPGS
Sbjct: 1195 PGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGS 1242



 Score =  139 bits (350), Expect = 8e-33
 Identities = 73/156 (46%), Positives = 88/156 (56%), Gaps = 8/156 (5%)

Query: 455  LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP-- 512
            + G PGPPGP G  G  GV G  G  G +G PG  GP G +G +G+PG  GP G   P  
Sbjct: 900  MMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNL 959

Query: 513  VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTG- 571
            +G +G  G  G  G  G  GP+G  G  GD G PG  G PG PGP GP+G PG+ G+ G 
Sbjct: 960  LGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGL 1019

Query: 572  --SPGQRGAMGPKGEPG---IQGPPGLPGPPGPPGS 602
               PG +G +G  G PG   ++GPPG  G PG PGS
Sbjct: 1020 IGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGS 1055



 Score =  139 bits (349), Expect = 1e-32
 Identities = 83/180 (46%), Positives = 95/180 (52%), Gaps = 35/180 (19%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRG---PKGDPGSLG---PLGPQGPQGQPGEA--GPVG 508
            G PG PG  G KGD G+ G  G  G   PKG+PG  G     GP GP G PG A  GP G
Sbjct: 1193 GPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKG 1252

Query: 509  ERGPVGPRGFP---------------------GLKGSKGSFGTGGPRGQPGPKGDIGPPG 547
              GP GP G P                     G+KG KG+ G  G  G PG KGD GPPG
Sbjct: 1253 NPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPG 1312

Query: 548  PEGPPGSPGPSGPQGKPGIAGKTGSPGQR------GAMGPKGEPGIQGPPGLPGPPGPPG 601
             +G PG PG +G +G PG+ G  G PG +      G+ GP+GEPG+ GPPG PG PGP G
Sbjct: 1313 LQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSG 1372



 Score =  138 bits (348), Expect = 1e-32
 Identities = 82/173 (47%), Positives = 91/173 (52%), Gaps = 24/173 (13%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRG---PKGDPGSL--GPLGPQGPQGQPGEAGPVGERG 511
           G PGPPG  G  G +G++GP G  G   PKG+PG    GP GP G  G  G  GP G+RG
Sbjct: 719 GIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRG 778

Query: 512 ---PVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPG-----PEGPPGSPGPSGPQGK 563
              P GP G  GL G  G  G  GP GQPGP G  G PG     P GPPG PGP G  G 
Sbjct: 779 FPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGL 838

Query: 564 PGIAGKTGSPG-----------QRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
            GI G+ G PG           +RG+ G  G PG  GPPG PG PG  G+  F
Sbjct: 839 HGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGF 891



 Score =  138 bits (347), Expect = 2e-32
 Identities = 78/158 (49%), Positives = 88/158 (55%), Gaps = 18/158 (11%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPG------------SLGPLGPQGPQGQPGEA 504
           G  GPPGPRG KGD G+ GP G +G +G PG              G  G  GPQG PG  
Sbjct: 66  GPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCN 125

Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564
           G  GERG  G  GFPGL+G  G  G  G +G+PG       PGP+G PG PGP G QG P
Sbjct: 126 GTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLP 185

Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
           G    TG PG    +GP G PG+ GPPG PG PGP G+
Sbjct: 186 G---PTGIPGP---IGPPGPPGLMGPPGPPGLPGPKGN 217



 Score =  138 bits (347), Expect = 2e-32
 Identities = 79/154 (51%), Positives = 84/154 (54%), Gaps = 11/154 (7%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVG--GRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
           L G PG PG  G  G  G KG  G  G G  G PG  G  G  GP G PG  G +G  GP
Sbjct: 679 LPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGP 738

Query: 513 VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572
            GP GFPG KG  G F   GP G PG  G  G  GP+G  G PGP GP   PG  G  G 
Sbjct: 739 PGPPGFPGPKGEPG-FALPGPPGPPGLPGFKGALGPKGDRGFPGPPGP---PGRTGLDGL 794

Query: 573 PGQRGAMGPKGEPGIQGPPGLP-----GPPGPPG 601
           PG +G +GP G+PG  GPPGLP     GPPGPPG
Sbjct: 795 PGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG 828



 Score =  138 bits (347), Expect = 2e-32
 Identities = 80/170 (47%), Positives = 88/170 (51%), Gaps = 22/170 (12%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGG------RGPKGDPGSLGPLG---PQGPQGQPGEAGPV 507
            G PG PG  G KGD G  G  G        G KGDPG  G  G    +GP G PG AGP 
Sbjct: 1294 GQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPE 1353

Query: 508  GERGPVGPRGFPGLKGSKGSF----GTGGP---------RGQPGPKGDIGPPGPEGPPGS 554
            GE G +GP G PGL G  G      G  GP         +G PGP+G  G PGP GPPG 
Sbjct: 1354 GEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGD 1413

Query: 555  PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQS 604
            PG +G  G  G  G+ G PG  G  G +G  G  GP GL GPPGPPG+ S
Sbjct: 1414 PGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSS 1463



 Score =  137 bits (345), Expect = 3e-32
 Identities = 78/180 (43%), Positives = 92/180 (51%), Gaps = 31/180 (17%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGP---------------------- 494
            G PGPPG +G  G  G+ GP G +G  G PG   P  P                      
Sbjct: 1158 GQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPG 1217

Query: 495  -QGPQGQPGEAGPVGERGPVGPRGFPG--LKGSKGSFGTGGPRGQPGPKGDIGPPGPEGP 551
              GP+G+PG  G  G +GP GP G PG  L+G KG+ G  GP G+PGP G  G PGPEGP
Sbjct: 1218 LPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGP 1277

Query: 552  PGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPG------PPGPPGSQSF 605
            PG PG  G +G+ G  G+ G PG  G  G +G PG+QG PG PG       PG PG   F
Sbjct: 1278 PGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGF 1337



 Score =  135 bits (340), Expect = 1e-31
 Identities = 79/200 (39%), Positives = 92/200 (46%), Gaps = 54/200 (27%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGP-----LGPQGPQGQPGEAGPVGER 510
           RG PGPPGP G  G  G+ GP G  GP G PG +GP     +G QGP G PG  GP+G+ 
Sbjct: 777 RGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQP 836

Query: 511 G-----------------------------------PVGPRGFPGLKGSKGSFGTGGPRG 535
           G                                   P+GP G PGL G  G+ G  G +G
Sbjct: 837 GLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKG 896

Query: 536 QPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPP---- 591
           + G  G  GPPGP G PG  G  G +G  G+ G+ G PG  G  G KGEPG+ GPP    
Sbjct: 897 EMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD 956

Query: 592 ----------GLPGPPGPPG 601
                     G PG PG PG
Sbjct: 957 PNLLGSKGEKGEPGLPGIPG 976



 Score =  135 bits (340), Expect = 1e-31
 Identities = 78/162 (48%), Positives = 89/162 (54%), Gaps = 16/162 (9%)

Query: 456  RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPG--SLGPLGPQGPQGQPGEAGPVGE---R 510
            +G  GPPGP G  G  G  G  G +G KGDPG  S+G  G  GP+G+PG  G  G    +
Sbjct: 1038 QGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIK 1097

Query: 511  GPVGPRGFPGLKGSKGSFGTGG------PRGQPGPKGDIGPPGPEGPPGSPGP---SGPQ 561
            G VG  G PGL G+ G+ G  G        G PGPKG  GPPG  G PG PGP    G  
Sbjct: 1098 GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHP 1157

Query: 562  GKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGL--PGPPGPPG 601
            G+PG  G+ G PGQ G  GP G+ G  G PG   PGPPG PG
Sbjct: 1158 GQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPG 1199



 Score =  135 bits (339), Expect = 1e-31
 Identities = 79/188 (42%), Positives = 93/188 (49%), Gaps = 43/188 (22%)

Query: 457  GAPGPPGP--------RGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVG 508
            G PGPPGP        +G KG+ G+ G  G  GPKG  G  G  G  G  GQPG  GP G
Sbjct: 947  GLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPG 1006

Query: 509  ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGP----------- 557
             +G  G  G PGL G  G  GT G  G PGP+G  GPPGP G PG PG            
Sbjct: 1007 PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG 1066

Query: 558  ------------SGPQGKPGIAGKTGSPGQRGAM------------GPKGEPGIQGPPGL 593
                         GP+G+PG+ G  G+PG +G++            G KG+PG+ G PG 
Sbjct: 1067 DPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGT 1126

Query: 594  PGPPGPPG 601
            PGPPGP G
Sbjct: 1127 PGPPGPKG 1134



 Score =  135 bits (339), Expect = 1e-31
 Identities = 74/149 (49%), Positives = 80/149 (53%), Gaps = 2/149 (1%)

Query: 453  TILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGP 512
            T  +G PGP GP G  G+ G+KG  G  G  G PG  G  G QGP G  G  G  G  G 
Sbjct: 1266 TGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGM 1325

Query: 513  VGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGS 572
             G  G PG+ G  G  G  G  G  GP+G+ G  GP GPPG PGPSG      I G  G 
Sbjct: 1326 KGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQ--SIIIKGDAGP 1383

Query: 573  PGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            PG  G  G KG PG QGP GLPGP GPPG
Sbjct: 1384 PGIPGQPGLKGLPGPQGPQGLPGPTGPPG 1412



 Score =  133 bits (335), Expect = 4e-31
 Identities = 72/168 (42%), Positives = 87/168 (51%), Gaps = 23/168 (13%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGR----------GPKGDPGSLGPLGPQGPQGQPGEAGP 506
           G PG PG +G +G+ GVKG  G            GP G PG  G  GP G  G PG+ G 
Sbjct: 457 GPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGE 516

Query: 507 VGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGP----------KGDIGPPGPEGPPGSPG 556
            G+ G  GP+G PG+ G+ G+ G  G +G+PG           KG++G PG  G PG PG
Sbjct: 517 KGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPG 576

Query: 557 PSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP---GPPGPPG 601
             G  G PG+ G  G PG     G +G PG  G PGLP   GP GPPG
Sbjct: 577 TPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG 624



 Score =  133 bits (335), Expect = 4e-31
 Identities = 80/178 (44%), Positives = 89/178 (50%), Gaps = 31/178 (17%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV------- 507
           L G PGPPG  GF G  G KG  G  GPKG PG  G  G  G  G  GE G +       
Sbjct: 498 LPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMK 557

Query: 508 GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGP---------KGDIGPPGPEGPPGSP--- 555
           G++G +G  G PGL G  G+ G  G  G PGP         KG+ GPPG  G PG P   
Sbjct: 558 GDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNI 617

Query: 556 --------GPSGPQGKPGIAGKTGSPGQRGAMGPKGEPG----IQGPPGLPGPPGPPG 601
                   GP GP G+ GI G  G+PGQ G  GPKG+PG      G PGLPG PG  G
Sbjct: 618 GPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675



 Score =  133 bits (335), Expect = 4e-31
 Identities = 76/166 (45%), Positives = 85/166 (51%), Gaps = 19/166 (11%)

Query: 453 TILRGAPGPPGPRGFKGDMGVKGP-----VGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV 507
           T L G PGP G  G  G  G  GP     +G +GP G PG  GP+G  G  G PGE G  
Sbjct: 789 TGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDP 848

Query: 508 GE-----RGPVGPRGFPGLKGSKGSF---------GTGGPRGQPGPKGDIGPPGPEGPPG 553
           G       GP G RG PG+ G+ G           G  G  G PG KG++G  GP GPPG
Sbjct: 849 GPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPG 908

Query: 554 SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGP 599
             G  G  G PG+ G  G  GQ G  GP GE G +G PGLPGPPGP
Sbjct: 909 PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGP 954



 Score =  133 bits (335), Expect = 4e-31
 Identities = 77/168 (45%), Positives = 86/168 (51%), Gaps = 23/168 (13%)

Query: 457  GAPGPPGPRGF---KGDMGVKGPVGGRGPKGDPGSLGP---LGPQGPQGQPGEAGPVGER 510
            G PG  G  GF   KG+MG+ GP G  GP G PG  G     G  G QGQPG  GP GE+
Sbjct: 881  GLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEK 940

Query: 511  GPVGPRGFPG--------LKGSKGSF---------GTGGPRGQPGPKGDIGPPGPEGPPG 553
            G  G  G PG        L GSKG           G  GP+G  G  GD G PG  G PG
Sbjct: 941  GSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPG 1000

Query: 554  SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
             PGP GP+G PG+ G+ G  G  G  G  G+ G  GP G+ GPPGP G
Sbjct: 1001 LPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSG 1048



 Score =  132 bits (332), Expect = 9e-31
 Identities = 76/170 (44%), Positives = 88/170 (51%), Gaps = 25/170 (14%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGP--------QGQPGEAGPVG 508
            G PG  G  G +G  G+ GP G +G KG+PG  GP GP  P        +G+PG  G  G
Sbjct: 917  GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPG 976

Query: 509  ERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD---------IGPPGPEGP------PG 553
              GP G +G PG  G  G  G  G  G PGPKG+         IGPPG +G       PG
Sbjct: 977  VSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG 1036

Query: 554  SPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQ--GPPGLPGPPGPPG 601
              G  GP G  G+ G+ GSPG  G  G KG+PGI   G PGLPGP G PG
Sbjct: 1037 PQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPG 1086



 Score =  130 bits (326), Expect = 5e-30
 Identities = 75/163 (46%), Positives = 88/163 (53%), Gaps = 20/163 (12%)

Query: 457  GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
            GAPGP GP G  G  G  G  G  G KG+ G +GP GP GP G PG +G  G +G  G +
Sbjct: 869  GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ 928

Query: 517  GFPGLKGSKGSFGTGGPRGQPGP-----------KGDIGPPGPEGPPGSPGPSGPQG--- 562
            G PGL G  G  G+ G  G PGP           KG+ G PG  G PG  GP G QG   
Sbjct: 929  GQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPG 988

Query: 563  ---KPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGS 602
               +PG++G+ G P   G  GPKG PG+ G PGL GPPG  G+
Sbjct: 989  DPGQPGLSGQPGLP---GPPGPKGNPGLPGQPGLIGPPGLKGT 1028



 Score =  129 bits (324), Expect = 8e-30
 Identities = 74/151 (49%), Positives = 80/151 (52%), Gaps = 11/151 (7%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G PGP G +G +G  G  G  G  GPKGDPG           G+PG  G  G  G VG  
Sbjct: 626 GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTIT-----QPGKPGLPGNPGRDGDVGLP 680

Query: 517 GFPGLKGSKGSFGTGGPRGQPGPKGD--IGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPG 574
           G PGL G  G  G  G +G+PG  G    GPPGP+G PG PGP G  G PG  G  G PG
Sbjct: 681 GDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPG 740

Query: 575 QRGAMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
             G  GPKGEPG      LPGPPGPPG   F
Sbjct: 741 PPGFPGPKGEPGF----ALPGPPGPPGLPGF 767



 Score =  129 bits (323), Expect = 1e-29
 Identities = 74/151 (49%), Positives = 78/151 (51%), Gaps = 9/151 (5%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPR 516
           G  G  G RGF G  G  G  G  GP+G PG   P G +G  G PG  GP G RGP G  
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPG---PRGQKGDDGIPGPPGPKGIRGPPGLP 98

Query: 517 GFPG---LKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSP 573
           GFPG   L G  G  G  GP+G PG  G  G  G  G PG PG  GP G PGI G  G P
Sbjct: 99  GFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEP 158

Query: 574 GQ---RGAMGPKGEPGIQGPPGLPGPPGPPG 601
           G        GPKG PG  GPPG+ G PGP G
Sbjct: 159 GSIIMSSLPGPKGNPGYPGPPGIQGLPGPTG 189



 Score =  126 bits (317), Expect = 5e-29
 Identities = 75/163 (46%), Positives = 82/163 (50%), Gaps = 27/163 (16%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           +G PG PGP G +G   + GP G  GP G PG  G +GP GP G PG  G +G       
Sbjct: 170 KGNPGYPGPPGIQG---LPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMG------- 219

Query: 516 RGFPGLKGSKGSFGTGGPRGQPG-------------PKGDIGPPGPEGPPGSPGPSGPQG 562
             F G KG KG  G  GP G PG              KGD G PG  GPPG PG  GP G
Sbjct: 220 LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPG 279

Query: 563 KP----GIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
            P    G  G+ G PG+RG  G  GE G  G PGLPG PG PG
Sbjct: 280 PPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPG 322



 Score =  126 bits (316), Expect = 7e-29
 Identities = 84/222 (37%), Positives = 103/222 (46%), Gaps = 52/222 (23%)

Query: 434 IVEEMKAVDTQHGEILRNVTILRGAPGPPG-------PRGFKGDMGVKGPVGGRGPKG-- 484
           I E+ + +D +  +  + +   RG PGPPG       P G KG+ G +G  G RG  G  
Sbjct: 244 ISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD 303

Query: 485 -------------DPGSLGPLGPQGPQGQPGEAGP----------------VGERGPVGP 515
                        DPG  G  G  G +GQ G+ GP                +GE+G +G 
Sbjct: 304 GENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGL 363

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGD--IGPPGPEGPPGSPGPSGPQGKPGIA--GKTG 571
            G PG KG +G  G  GP G PGP G   +GPPGP G PG  G  G +G PGI+  G  G
Sbjct: 364 PGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPG 423

Query: 572 SPGQRGAMGPKGEPGIQGP----------PGLPGPPGPPGSQ 603
             GQ GA G  G PG  GP          PG PGPPG PG +
Sbjct: 424 LDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDK 465



 Score =  125 bits (315), Expect = 9e-29
 Identities = 70/149 (46%), Positives = 82/149 (55%), Gaps = 3/149 (2%)

Query: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGP 515
           RG PG  G  G  G  G +GP G RG KGD G  GP GP+G +G PG  G  G  G  G 
Sbjct: 50  RGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGM 109

Query: 516 RGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQ 575
            G  G  G +G  G  G +G+ G  G  G PG +GPPG PG  G +G+PG    +  PG 
Sbjct: 110 PGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGP 169

Query: 576 RGAMGPKGEPGIQ---GPPGLPGPPGPPG 601
           +G  G  G PGIQ   GP G+PGP GPPG
Sbjct: 170 KGNPGYPGPPGIQGLPGPTGIPGPIGPPG 198



 Score =  125 bits (315), Expect = 9e-29
 Identities = 86/216 (39%), Positives = 96/216 (44%), Gaps = 65/216 (30%)

Query: 453 TILRGAPGPPGPRGF---KGDMGVKGPVGG-----RGPKGDPGSLGPLGPQGPQGQ---- 500
           T + G  GPPGP G     G  G+ GP G      +GPKG+ G  G  GP GP GQ    
Sbjct: 188 TGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQ 247

Query: 501 ---------------PGEAGPVGE---RGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGD 542
                          PG+ GP G    RGP GP G  G KG KG  G  G RG+PG  G+
Sbjct: 248 KRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGE 305

Query: 543 IGPPGPEGPPGSP---------------GPSGPQGKPGIA-------------GKTGSPG 574
            G PG  G PG P               G +GP G PG+              G  G PG
Sbjct: 306 NGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPG 365

Query: 575 QRGAMGPKGEPGIQGPPGLPGPP-----GPPGSQSF 605
             G  G +G PGIQGPPGLPGPP     GPPG   F
Sbjct: 366 LPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGF 401



 Score =  125 bits (313), Expect = 1e-28
 Identities = 83/204 (40%), Positives = 95/204 (46%), Gaps = 55/204 (26%)

Query: 457 GAPGPPG---PR-------GFKGDMGVKGPVGGRGPKGDPGSLGP-----------LGPQ 495
           G PGPPG   PR       G KG++G+ G  G +G +G PG  GP           +GP 
Sbjct: 337 GPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPP 396

Query: 496 GPQGQPGEAGPVGERGPVGPR--GFPGLKGSKGSFGTGGPRGQPGP----KGDIGPPGPE 549
           GP G PGE G  G+ GP G    G PGL G  G+ G  GP G  GP      +I  PGP 
Sbjct: 397 GPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPP 456

Query: 550 GPPGSPGP-------------------------SGPQGKPGIAGKTGSPGQRGAMGPKGE 584
           GPPGSPG                          SGP G+PG+ G  G PG  G  G KGE
Sbjct: 457 GPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGE 516

Query: 585 PG---IQGPPGLPGPPGPPGSQSF 605
            G     GP GLPG PG PG+  F
Sbjct: 517 KGQAGATGPKGLPGIPGAPGAPGF 540



 Score =  124 bits (310), Expect = 3e-28
 Identities = 71/148 (47%), Positives = 79/148 (53%), Gaps = 3/148 (2%)

Query: 459 PGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGF 518
           PGPPGP G  GD G++G  G +G KGD      +G  G  G PG+ G  G  GP G  GF
Sbjct: 453 PGPPGPPGSPGDKGLQGEQGVKGDKGDT-CFNCIGT-GISGPPGQPGLPGLPGPPGSLGF 510

Query: 519 PGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGP-QGKPGIAGKTGSPGQRG 577
           PG KG KG  G  GP+G PG  G  G PG  G  G PG      G  G  G+ GSPG  G
Sbjct: 511 PGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPG 570

Query: 578 AMGPKGEPGIQGPPGLPGPPGPPGSQSF 605
             G  G PG  G PGLPGP G PG  +F
Sbjct: 571 LPGLPGTPGQDGLPGLPGPKGEPGGITF 598



 Score =  123 bits (309), Expect = 4e-28
 Identities = 76/177 (42%), Positives = 85/177 (48%), Gaps = 33/177 (18%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQP---GEAGPVGERGPV 513
           G  G PGP+G  G  G KG    RG  G PG  G  GP GP G P   GE G +      
Sbjct: 111 GHDGAPGPQGIPGCNGTKGE---RGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLP 167

Query: 514 GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPP---GPEGPPGSPGP--------SGPQG 562
           GP+G PG  G  G  G  GP G PGP G  GPP   GP GPPG PGP         GP+G
Sbjct: 168 GPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKG 227

Query: 563 KPGIAGKTGSPG----------------QRGAMGPKGEPGIQGPPGLPGPPGPPGSQ 603
           + G  G  G PG                Q+G  G  G+ G  GPPG+ GPPGPPG +
Sbjct: 228 EKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGE 284



 Score =  123 bits (309), Expect = 4e-28
 Identities = 74/170 (43%), Positives = 83/170 (48%), Gaps = 28/170 (16%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGE--AGPVGERGPVG 514
           G PGPPG +G  G  G+ GP+G  GP G  G  GP G  GP+G  G    GP GE+G  G
Sbjct: 174 GYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQG 233

Query: 515 PRGFPGLKGS-------------KGSFGTGGPRGQPGPKGDIGPPGP----------EGP 551
            +G PG  G              KG  G  G RG PGP G  GPPGP          +G 
Sbjct: 234 LQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGE 293

Query: 552 PGS---PGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPG 598
           PG    PG  G  G+PGI G  G PG  G  G  GE G +G  G PGPPG
Sbjct: 294 PGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPG 343



 Score =  103 bits (258), Expect = 4e-22
 Identities = 61/130 (46%), Positives = 64/130 (49%), Gaps = 27/130 (20%)

Query: 499 GQPGEAGPV------------GERGPVGPRGFPGLKGSKGSFGTGGPRGQPGP---KGDI 543
           GQP EA               G +G  G RGFPGL+G  G  G  GP G PGP   KGD 
Sbjct: 21  GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80

Query: 544 GPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGP------------P 591
           G PGP GP G  GP G  G PG  G  G PG  GA GP+G PG  G             P
Sbjct: 81  GIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP 140

Query: 592 GLPGPPGPPG 601
           GL GPPGPPG
Sbjct: 141 GLQGPPGPPG 150



 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 45/106 (42%), Positives = 52/106 (49%), Gaps = 21/106 (19%)

Query: 454  ILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPV 513
            I++G  GPPG  G  G  G+ GP                  QGPQG PG  GP G+    
Sbjct: 1376 IIKGDAGPPGIPGQPGLKGLPGP------------------QGPQGLPGPTGPPGD---P 1414

Query: 514  GPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSG 559
            G  G PG  G+ G  G  G  GQPG +G  GPPGP+G  G PGP G
Sbjct: 1415 GRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460



 Score = 59.7 bits (143), Expect = 8e-09
 Identities = 33/71 (46%), Positives = 37/71 (52%), Gaps = 12/71 (16%)

Query: 535 GQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLP 594
           G  G KG+ G PG EG PG PG  GP+G PG  G+            KG+ GI GPPG  
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQ------------KGDDGIPGPPGPK 89

Query: 595 GPPGPPGSQSF 605
           G  GPPG   F
Sbjct: 90  GIRGPPGLPGF 100


>gi|145701009 acetylcholinesterase collagen-like tail subunit
           isoform III precursor [Homo sapiens]
          Length = 421

 Score =  150 bits (380), Expect = 2e-36
 Identities = 77/154 (50%), Positives = 97/154 (62%), Gaps = 12/154 (7%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLG---PQGPQGQPGEAGPVG---ER 510
           G PG  GP+G KG++G  G  G  GP G PG  GP+G   P+GP+G+ G+ G +G    R
Sbjct: 77  GLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSR 136

Query: 511 GPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIA--- 567
           GP+G +G+PG +G KGS    G +G  GPKG+ G PG  G  G  G  GP+G+PGIA   
Sbjct: 137 GPMGSKGYPGSRGEKGS---RGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHR 193

Query: 568 GKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG 601
           G TG PG+RG  G KG+ G+ GPPG PGP G PG
Sbjct: 194 GPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPG 227



 Score =  136 bits (342), Expect = 6e-32
 Identities = 75/154 (48%), Positives = 89/154 (57%), Gaps = 19/154 (12%)

Query: 457 GAPGPPGPRGFKGDMGVKGPVGGRGP------------KGDPGSLGPLGPQGPQGQPGEA 504
           G PGP GPRG KGD+G+ G  G RGP            KG  G  G LGP+G +G PG  
Sbjct: 113 GWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFP 172

Query: 505 GPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKP 564
           G +G++G +GP+G PG+ G +G  G  G RG+ G KGD    G  GPPG PGPSG  G+P
Sbjct: 173 GMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGD---SGVMGPPGKPGPSGQPGRP 229

Query: 565 GIAGKTGSPGQRGAMGPKGEPGIQGPPG--LPGP 596
           G  G    P  +  MGPKGE G  GPPG  L GP
Sbjct: 230 GPPGP--PPAGQLIMGPKGERGFPGPPGRCLCGP 261



 Score = 90.1 bits (222), Expect = 5e-18
 Identities = 55/121 (45%), Positives = 63/121 (52%), Gaps = 28/121 (23%)

Query: 508 GERGPVGPRGFPGL---KGSKGSFGTGGPRGQPGP------KGDIGPPGPEGP------- 551
           G R P GP G PG    KG KG  G  G +G+PGP       G IG PGPEGP       
Sbjct: 69  GGRSP-GPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDL 127

Query: 552 -----PGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGL------PGPPGPP 600
                PGS GP G +G PG  G+ GS G++G +GPKGE G  G PG+       GP G P
Sbjct: 128 GMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEP 187

Query: 601 G 601
           G
Sbjct: 188 G 188



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 35/78 (44%), Positives = 40/78 (51%)

Query: 528 FGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGI 587
           F  G   G PG  G  GP G +G  G PG  G  G PG+ G  G  G  G  GP+GE G 
Sbjct: 67  FRGGRSPGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGD 126

Query: 588 QGPPGLPGPPGPPGSQSF 605
            G  GLPG  GP GS+ +
Sbjct: 127 LGMMGLPGSRGPMGSKGY 144



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 32/71 (45%), Positives = 35/71 (49%), Gaps = 6/71 (8%)

Query: 455 LRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGE--RGP 512
           + G  GP G  G +G  G KG  G  GP G PG  G  G  GP G P    P G+   GP
Sbjct: 189 IAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP----PAGQLIMGP 244

Query: 513 VGPRGFPGLKG 523
            G RGFPG  G
Sbjct: 245 KGERGFPGPPG 255


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.136    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,102,392
Number of Sequences: 37866
Number of extensions: 1949947
Number of successful extensions: 65679
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 400
Number of HSP's successfully gapped in prelim test: 1079
Number of HSP's that attempted gapping in prelim test: 10338
Number of HSP's gapped (non-prelim): 13260
length of query: 606
length of database: 18,247,518
effective HSP length: 108
effective length of query: 498
effective length of database: 14,157,990
effective search space: 7050679020
effective search space used: 7050679020
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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