Guide to the Human Genome
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Search of human proteins with 31543148

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31543148 hypothetical protein LOC79173 [Homo sapiens]
         (637 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31543148 hypothetical protein LOC79173 [Homo sapiens]             1310   0.0  
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      66   9e-11
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      62   2e-09
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          62   2e-09
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]     59   1e-08
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       58   2e-08
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       57   5e-08
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                57   7e-08
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              56   9e-08
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]          54   4e-07
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]      54   4e-07
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...    54   4e-07
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    54   6e-07
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    54   6e-07
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...    54   6e-07
gi|91208420 bassoon protein [Homo sapiens]                             53   1e-06
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...    53   1e-06
gi|119508426 alpha 3 type IX collagen [Homo sapiens]                   53   1e-06
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]    52   2e-06
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    51   3e-06
gi|150418009 transforming, acidic coiled-coil containing protein...    51   3e-06
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    51   4e-06
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    51   4e-06
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    51   4e-06
gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens]               51   4e-06
gi|50511941 EMI domain containing 1 [Homo sapiens]                     50   5e-06
gi|194294532 alpha 1 type XIII collagen isoform 20 [Homo sapiens]      50   6e-06
gi|22027607 alpha 1 type XIII collagen isoform 18 [Homo sapiens]       50   6e-06
gi|22027605 alpha 1 type XIII collagen isoform 17 [Homo sapiens]       50   6e-06
gi|22027603 alpha 1 type XIII collagen isoform 16 [Homo sapiens]       50   6e-06

>gi|31543148 hypothetical protein LOC79173 [Homo sapiens]
          Length = 637

 Score = 1310 bits (3391), Expect = 0.0
 Identities = 637/637 (100%), Positives = 637/637 (100%)

Query: 1   MTKRKKLRTSGEGLCPPKPLKNPRLGDFYGDPQSSMLGCLHHPEEPEGKLGPVPSTQQHG 60
           MTKRKKLRTSGEGLCPPKPLKNPRLGDFYGDPQSSMLGCLHHPEEPEGKLGPVPSTQQHG
Sbjct: 1   MTKRKKLRTSGEGLCPPKPLKNPRLGDFYGDPQSSMLGCLHHPEEPEGKLGPVPSTQQHG 60

Query: 61  EEPGKAVSSSPDEETGSPCRLLRQPEKEPAPLPPSQNSFGRFVPQFAKSRKTVTRKEEMK 120
           EEPGKAVSSSPDEETGSPCRLLRQPEKEPAPLPPSQNSFGRFVPQFAKSRKTVTRKEEMK
Sbjct: 61  EEPGKAVSSSPDEETGSPCRLLRQPEKEPAPLPPSQNSFGRFVPQFAKSRKTVTRKEEMK 120

Query: 121 DEDRGSGAFSLETIAESSAQSPGCQLLVETLGVPLQEATELGDPTQADSARPEQSSQSPV 180
           DEDRGSGAFSLETIAESSAQSPGCQLLVETLGVPLQEATELGDPTQADSARPEQSSQSPV
Sbjct: 121 DEDRGSGAFSLETIAESSAQSPGCQLLVETLGVPLQEATELGDPTQADSARPEQSSQSPV 180

Query: 181 QAVPGSGDSQPDDPPDRGTGLSASQRASQDHLSEQGADDSKPETDRVPGDGGQKEHLPSI 240
           QAVPGSGDSQPDDPPDRGTGLSASQRASQDHLSEQGADDSKPETDRVPGDGGQKEHLPSI
Sbjct: 181 QAVPGSGDSQPDDPPDRGTGLSASQRASQDHLSEQGADDSKPETDRVPGDGGQKEHLPSI 240

Query: 241 DSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPASAPTSGPAPGLGPASWCLE 300
           DSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPASAPTSGPAPGLGPASWCLE
Sbjct: 241 DSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPASAPTSGPAPGLGPASWCLE 300

Query: 301 PGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPD 360
           PGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPD
Sbjct: 301 PGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPD 360

Query: 361 GQASAISPASPRRKAADGGHRRALPGCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLA 420
           GQASAISPASPRRKAADGGHRRALPGCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLA
Sbjct: 361 GQASAISPASPRRKAADGGHRRALPGCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLA 420

Query: 421 LAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELGGQNLERDLEGFRVSPQAS 480
           LAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELGGQNLERDLEGFRVSPQAS
Sbjct: 421 LAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELGGQNLERDLEGFRVSPQAS 480

Query: 481 VVLEHREIADDPLQEPGAQQGIPDTTSELAGQRDHLPHSADQGTWADSLAVELDFLLDSQ 540
           VVLEHREIADDPLQEPGAQQGIPDTTSELAGQRDHLPHSADQGTWADSLAVELDFLLDSQ
Sbjct: 481 VVLEHREIADDPLQEPGAQQGIPDTTSELAGQRDHLPHSADQGTWADSLAVELDFLLDSQ 540

Query: 541 IQDALDASDFEAPPEQLFPSGNKPGPCWPGPSSHANGDPVAVAKAQPSRLIMGTHRDLEA 600
           IQDALDASDFEAPPEQLFPSGNKPGPCWPGPSSHANGDPVAVAKAQPSRLIMGTHRDLEA
Sbjct: 541 IQDALDASDFEAPPEQLFPSGNKPGPCWPGPSSHANGDPVAVAKAQPSRLIMGTHRDLEA 600

Query: 601 FKRLNYRKTKLGGKAPLPYPSKGPGNIPRGDPPWREL 637
           FKRLNYRKTKLGGKAPLPYPSKGPGNIPRGDPPWREL
Sbjct: 601 FKRLNYRKTKLGGKAPLPYPSKGPGNIPRGDPPWREL 637


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 66.2 bits (160), Expect = 9e-11
 Identities = 136/495 (27%), Positives = 165/495 (33%), Gaps = 67/495 (13%)

Query: 16  PPKPLKNPRLGD------FYGDPQSSMLGCL----HHPEEPEGKLGPVPSTQQHG----- 60
           PP P   P LG        YG  + S  G        P  P G  GP  +    G     
Sbjct: 146 PPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPP 205

Query: 61  EEPGKAVSSSPDEETGSPCRLLRQPEKEPAPLPPSQNSFGRFVPQFAKSRKTVTRKEEMK 120
            EPG+  +S P    G P    +  +   A  P      G   PQ A+          MK
Sbjct: 206 GEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMK 265

Query: 121 DEDRGSGAFSLETIA-----ESSAQSPGCQLLVETLGVPLQEATELGDPTQADSARPEQS 175
                SG    +  A     +    SPG       +G P     E G P     A    +
Sbjct: 266 GHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMG-PRGLPGERGRPGAPGPAGARGN 324

Query: 176 SQSPVQAVPGSGDSQPDDPPDRGTGLSASQRAS-QDHLSEQGADDSKPETDRVPGDGGQK 234
             +   A P  G + P  PP     + A   A  Q     +G    + E    PG  G  
Sbjct: 325 DGATGAAGP-PGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGP-PGPAGAA 382

Query: 235 EHL--PSIDSE-GEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPASAPTSGPAPG 291
                P  D + G K   GAP   GA    GA  P GPQ  G G P  P        APG
Sbjct: 383 GPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQ--GPGGPPGPKGNSGEPGAPG 440

Query: 292 -LGPASWCLEPGSV-AQGSPDPQQTPSRMGREGEGTHSSL--------GCSSLGMVVIAD 341
             G      EPG V  QG P P     + G  GE   + L        G  S G    AD
Sbjct: 441 SKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPG-AD 499

Query: 342 LSTDPTELEERALEVAGPDGQASAISPASPRRKAADGGH--RRALPGCTSLTGE------ 393
               P           GP G+  +  PA P+    + G      LPG   LTG       
Sbjct: 500 GVAGP----------KGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGP 549

Query: 394 --TTGESGEAGQDGK--PPGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGPCVNQK 449
              TG  G AGQDG+  PPG       A +   PG   +   AG+ G A     P     
Sbjct: 550 DGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGA---AGEPGKAGERGVP--GPP 604

Query: 450 QEPGPAQEEAELGGQ 464
              GPA ++ E G Q
Sbjct: 605 GAVGPAGKDGEAGAQ 619



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 69/248 (27%), Positives = 88/248 (35%), Gaps = 30/248 (12%)

Query: 228  PGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPASAPTSG 287
            PG  G         ++G+   +G P + GA+  AG   P GP   G   P     AP + 
Sbjct: 805  PGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGP--AGPPGPIGNVGAPGAK 862

Query: 288  PAPG-LGPASWCLEPGSVAQ-------GSPDPQQTPSRMGRE-GEGTHSSLGCSSLGMVV 338
             A G  GP      PG+  +       G+  P   P   G+E G+G     G    G   
Sbjct: 863  GARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETG--PAGRPG 920

Query: 339  IADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADGG--------HRRALPGCTSL 390
                   P    E+     G DG A A     P+  A   G          R  PG    
Sbjct: 921  EVGPPGPPGPAGEKG--SPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGP 978

Query: 391  TGE--TTGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGP-CVN 447
            +GE    G SG +G+ G PPG   +GP   LA  PG        G  G    D  P    
Sbjct: 979  SGEPGKQGPSGASGERG-PPGP--MGP-PGLAGPPGESGREGAPGAEGSPGRDGSPGAKG 1034

Query: 448  QKQEPGPA 455
             + E GPA
Sbjct: 1035 DRGETGPA 1042



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 82/317 (25%), Positives = 108/317 (34%), Gaps = 66/317 (20%)

Query: 157 EATELGDPTQADSA-RPEQSSQSPVQAVPGS-------GDSQPDDPPDRGTGLSASQRAS 208
           +A  +G P    +A  P ++ +  V   PG+       G++    PP  G    A +R  
Sbjct: 576 QAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPP--GPAGPAGERGE 633

Query: 209 QDHLSEQGADD-----SKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGA 263
           Q      G          P     PG+ G    L +    G + +RG P E G Q   G 
Sbjct: 634 QGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPG- 692

Query: 264 GLPGGPQEEGDGVPCTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREG- 322
             P GP+   +G P    +   +G APG         PGS  QG+P  Q  P   G  G 
Sbjct: 693 --PAGPR-GANGAPGNDGAKGDAG-APG--------APGS--QGAPGLQGMPGERGAAGL 738

Query: 323 ---EGTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKA-ADG 378
              +G     G         AD S              G DG      P  P   A A G
Sbjct: 739 PGPKGDRGDAGPKG------ADGS-------------PGKDGVRGLTGPIGPPGPAGAPG 779

Query: 379 GHRRALPGCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGAGDSGHA 438
               + P   +      G  G+ G+ G P      GP  +       GE     GD+G A
Sbjct: 780 DKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGE----PGDAG-A 834

Query: 439 SPDTGPCVNQKQEPGPA 455
             D GP       PGPA
Sbjct: 835 KGDAGP-------PGPA 844



 Score = 38.1 bits (87), Expect = 0.025
 Identities = 54/199 (27%), Positives = 61/199 (30%), Gaps = 65/199 (32%)

Query: 250  GAPQEGGAQRTAGA----GLPGGPQEEGDGVPCTPASAPTSGPAPGLGPASWCLEPGSVA 305
            G P E G +   GA    G  G P  +GD     PA  P    APG             A
Sbjct: 1007 GPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPP---GAPG-------------A 1050

Query: 306  QGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQASA 365
             G+P P     + G  GE                    T P          AGP G   A
Sbjct: 1051 PGAPGPVGPAGKSGDRGE--------------------TGPA-------GPAGPVGPVGA 1083

Query: 366  ISPASPRRKAADGGHRRALPGCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLALAPGS 425
              PA P+    D G               TGE G+ G  G      L GP       PGS
Sbjct: 1084 RGPAGPQGPRGDKGE--------------TGEQGDRGIKGHRGFSGLQGPPG----PPGS 1125

Query: 426  GESMMGAGDSGHASPDTGP 444
                  +G SG A P   P
Sbjct: 1126 PGEQGPSGASGPAGPRGPP 1144



 Score = 36.6 bits (83), Expect = 0.073
 Identities = 68/259 (26%), Positives = 84/259 (32%), Gaps = 21/259 (8%)

Query: 43   PEEPEGKLGPVPSTQQHGEE--PG-KAVSSSPDEETGSPCRLLRQPEKEPAPLPPSQNSF 99
            P+   G+ G V    Q GE   PG    S  P ++  S     R P   P P+ P     
Sbjct: 951  PQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGP---PGPMGPP---- 1003

Query: 100  GRFVPQFAKSRKTVTRKEEMKDEDRGSGAFSLETIAESSAQSPGCQLLVETLGVPLQEAT 159
            G   P     R+     E     D   GA   +      A  PG        G P+  A 
Sbjct: 1004 GLAGPPGESGREGAPGAEGSPGRDGSPGAKG-DRGETGPAGPPGAPGAPGAPG-PVGPAG 1061

Query: 160  ELGDPTQADSARPEQSSQSPVQAVPGSGDSQPDDPP-DRGTGLSASQRASQDHLSEQGAD 218
            + GD  +   A P      PV  V   G + P  P  D+G       R  + H    G  
Sbjct: 1062 KSGDRGETGPAGPA----GPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQ 1117

Query: 219  DSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQ-EEGDGVP 277
               P     PG+ G           G     GAP + G     G   P GP+   GD  P
Sbjct: 1118 -GPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGP 1176

Query: 278  CTPASAPTSGPAPGLGPAS 296
              P   P  GP    GP S
Sbjct: 1177 VGPPGPP--GPPGPPGPPS 1193



 Score = 34.3 bits (77), Expect = 0.36
 Identities = 42/158 (26%), Positives = 49/158 (31%), Gaps = 10/158 (6%)

Query: 164  PTQADSARPEQSSQSPVQAVPGSGDSQPDDPPDRGTGLSASQRASQDHLSEQGADDSKPE 223
            P     A     +  PV     SGD     P   G         ++     QG    K E
Sbjct: 1041 PAGPPGAPGAPGAPGPVGPAGKSGDRGETGPA--GPAGPVGPVGARGPAGPQGPRGDKGE 1098

Query: 224  TDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEG-----DGVPC 278
            T    GD G K H      +G     G+P E G    +G   P GP         DG+  
Sbjct: 1099 TGE-QGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNG 1157

Query: 279  TPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPS 316
             P      GP    G A     PG    G P P   PS
Sbjct: 1158 LPGPIGPPGPRGRTGDAGPVGPPG--PPGPPGPPGPPS 1193


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 83/296 (28%), Positives = 107/296 (36%), Gaps = 47/296 (15%)

Query: 184  PGS-GDSQPDDPPDRGTGLSASQRASQDHLSEQGADDSKPE--TDRVPGDGGQKEHLPSI 240
            PG  G++ P  P   G   +  Q        E+GA   K E     V G  G        
Sbjct: 797  PGERGETGPPGPA--GFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPP 854

Query: 241  DSEGEKPDRGAPQEGGAQRTAGA-GLPGGPQEEGDGVPCTPASAPTSGPAPGLGPASWCL 299
              +G K +RG+P   GA    GA GLPG P   G+  P  P+ +P     P  GPA    
Sbjct: 855  GPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPP--GPAGNTG 912

Query: 300  EPGSVAQGSPDPQQTPSRMGREGE-GTHSSLGCSSLGMVVIADLSTDPTELEERALEVAG 358
             PGS   G   P+    + G +G  G     G    G + IA ++         A  +AG
Sbjct: 913  APGS--PGVSGPKGDAGQPGEKGSPGAQGPPGAP--GPLGIAGIT--------GARGLAG 960

Query: 359  PDGQASAISPASPRRKAADGGHRRALPGCTSLTGE-----------TTGESGEAGQDGKP 407
            P G         P+    + G     PG   L+GE             G +GE G+DG P
Sbjct: 961  PPGMPGPRGSPGPQGVKGESGK----PGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNP 1016

Query: 408  PGDVLVGPTASLALAPGSGESMMGAGDSG-HASPDTGPCVNQKQEPGPAQEEAELG 462
              D L          PG   S  G GD G + SP           PGP     + G
Sbjct: 1017 GSDGL----------PGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSG 1062



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 82/291 (28%), Positives = 98/291 (33%), Gaps = 56/291 (19%)

Query: 181 QAVPG-SGDSQPDDPPD-RGTGLSASQRASQDHLSEQGADDS--KPETDRVPGDGGQKEH 236
           Q  PG +G++ P  PP   G G              QG   +   P  +  PG+ G K  
Sbjct: 605 QGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGD 664

Query: 237 LPSIDSEGEKPDRGAPQEGGAQRTAGA-GLPGG---PQEEGDGVPCTPASAPTSGPAPGL 292
             +  + G K D GAP E G    AGA GL GG   P  EG      P   P +   PGL
Sbjct: 665 AGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGL 724

Query: 293 GPASWCLEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIADLSTDPTELEER 352
                  E G +  GSP P+      G  G G     G                      
Sbjct: 725 QGMPG--ERGGL--GSPGPKGDKGEPG--GPGADGVPGKD-------------------- 758

Query: 353 ALEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGETTGESGEAGQDGKPPGDVL 412
                GP G    I P  P  +  D G   A PG   + G   G  GE G+ G PPG   
Sbjct: 759 -----GPRGPTGPIGPPGPAGQPGDKGEGGA-PGLPGIAG-PRGSPGERGETG-PPG--- 807

Query: 413 VGPTASLALAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELGG 463
               A    APG      G G+ G           +K E GP       GG
Sbjct: 808 ---PAGFPGAPGQNGEPGGKGERG--------APGEKGEGGPPGVAGPPGG 847



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 85/287 (29%), Positives = 101/287 (35%), Gaps = 71/287 (24%)

Query: 222 PETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGA----------GLPGGPQE 271
           P T   PG  G K  +    S G     G   E G Q  AGA          G PGG  E
Sbjct: 338 PGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGE 397

Query: 272 EGD-GVPCTPASAPTSGP--------APGL-GPASWCLEPG-SVAQGSPDPQ-------- 312
            G  G+P  P      GP        APGL G A    EPG + A+G P P+        
Sbjct: 398 MGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAG---EPGKNGAKGEPGPRGERGEAGI 454

Query: 313 -QTPSRMGREG-EGTHSSLGCSSL----------GMVVIADLSTDPTELEERALEVAGPD 360
              P   G +G +G+    G + L          G    A  +  P E         GP 
Sbjct: 455 PGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGE--------KGPA 506

Query: 361 GQASAISPASPRRKAADGGHRRALPGCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLA 420
           G+  A  PA PR  A + G R  +PG   + G   G  G  G DGKP      GP     
Sbjct: 507 GERGAPGPAGPRGAAGEPG-RDGVPGGPGMRG-MPGSPGGPGSDGKP------GP----- 553

Query: 421 LAPGSGESMMGAGDSGHASPDTGPCV----NQKQEPGPAQEEAELGG 463
             PGS       G  G + P   P V      K   G   +  E GG
Sbjct: 554 --PGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGG 598



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 63/226 (27%), Positives = 84/226 (37%), Gaps = 36/226 (15%)

Query: 219  DSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQ----EEGD 274
            D  P +D +PG  G      S   +G++ + G+P   GA    G   P GP     + G+
Sbjct: 1013 DGNPGSDGLPGRDG------SPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGE 1066

Query: 275  GVPCTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGE-GTHSSLGCSS 333
              P  PA AP        GPA         ++G+P PQ      G  GE G     G   
Sbjct: 1067 SGPAGPAGAP--------GPAG--------SRGAPGPQGPRGDKGETGERGAAGIKGHRG 1110

Query: 334  LGMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADGGHRRAL--PGCTSLT 391
                  A  S  P   ++ A+   GP G    + P+ P  K    GH   +  PG     
Sbjct: 1111 FPGNPGAPGSPGPAG-QQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNR 1169

Query: 392  GE--TTGESGEAGQDGKPPGDVLVGP----TASLALAPGSGESMMG 431
            GE  + G  G  GQ G P      GP      + A+A   GE   G
Sbjct: 1170 GERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGG 1215



 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 86/310 (27%), Positives = 98/310 (31%), Gaps = 60/310 (19%)

Query: 169 SARPEQSSQSPVQAVPGS-GDSQPDDPPDRGTGLSASQRASQDHLSEQGADDSKPETDR- 226
           S  P        Q  PG  G + P  PP     +  S  A +D   E G      E    
Sbjct: 188 SGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKD--GESGRPGRPGERGLP 245

Query: 227 ----------VPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGV 276
                     +PG  G K H       GEK + GAP   G       GLPG   E G   
Sbjct: 246 GPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGEN-----GLPG---ENGAPG 297

Query: 277 PCTPASAPTSGPAPGLGPASWCL--EPGSVAQGSPDPQQTPSRMGREGE-GTHSSLG-CS 332
           P  P  AP     PGL  A+     +    + G P P   P   G  G  G    +G   
Sbjct: 298 PMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAG 357

Query: 333 SLGMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTG 392
           S G         +P           GP G A A  P  P             PG     G
Sbjct: 358 SPGSNGAPGQRGEP-----------GPQGHAGAQGPPGP-------------PGINGSPG 393

Query: 393 ETTGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGPCVNQKQEP 452
              GE G AG  G P      GP    A A G+     GAG+ G            K EP
Sbjct: 394 -GKGEMGPAGIPGAPGLMGARGPPGP-AGANGAPGLRGGAGEPGKN--------GAKGEP 443

Query: 453 GPAQEEAELG 462
           GP  E  E G
Sbjct: 444 GPRGERGEAG 453



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 75/302 (24%), Positives = 98/302 (32%), Gaps = 85/302 (28%)

Query: 152 GVPLQEATELGDPTQADSARPEQSSQSPVQAVPG-SGDSQPDDPPDRGTGLSASQRASQD 210
           GVP  +  +  D +  +         +  +  PG  G + P+  P  G    A +R +  
Sbjct: 456 GVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIP--GEKGPAGERGAPG 513

Query: 211 HLSEQGADDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQ 270
               +GA   +P  D VPG  G                RG P           G PGGP 
Sbjct: 514 PAGPRGAA-GEPGRDGVPGGPGM---------------RGMP-----------GSPGGP- 545

Query: 271 EEGDGVPCTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGE-GTHSSL 329
              DG P  P S   SG     GP+    +PG    G P P+      G+ GE G     
Sbjct: 546 -GSDGKPGPPGSQGESGRPGPPGPSGPRGQPG--VMGFPGPKGNDGAPGKNGERGGPGGP 602

Query: 330 GCSSLGMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADGGHR-------- 381
           G                           GP G+     P  P      GG +        
Sbjct: 603 G-------------------------PQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGP 637

Query: 382 ---RALPGCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGAGDSGHA 438
              + LPG    TG   GE+G+ G+ G P GD         A APG+      AG  G  
Sbjct: 638 QGLQGLPG----TGGPPGENGKPGEPG-PKGD---------AGAPGAPGGKGDAGAPGER 683

Query: 439 SP 440
            P
Sbjct: 684 GP 685


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 110/462 (23%), Positives = 152/462 (32%), Gaps = 89/462 (19%)

Query: 62   EPGKAVSSSPDEETGSPCRLL---------RQPEKEPAPLPPSQNSFGRFVPQFAKSRKT 112
            +PG+     P  E G+P +++         R+ +  P+  P  +   G   P+       
Sbjct: 1336 DPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPG 1395

Query: 113  VTRKEEMKDE-DRGSGAFSLETIAESSAQSPGCQLLVETLGVPLQEATELGDPTQADSAR 171
               K +  D  +RG        IA      PG        G P  +   +G P +     
Sbjct: 1396 TAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLP------GSPGPQGP-VGPPGKKGEKG 1448

Query: 172  PEQSSQSPVQAVPGS-GDSQPDDPP-------DRGTGLSASQRASQDHLSEQGADDSK-- 221
              +     +   PGS G+  P  PP       DRG      +   +      G   S+  
Sbjct: 1449 DSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGL 1508

Query: 222  PETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPA 281
            P     PG  G +        +GEK + G P   G     G  + G   E+GD  P  P 
Sbjct: 1509 PGVAGRPGAKGPEGPPGPTGRQGEKGEPGRP---GDPAVVGPAVAGPKGEKGDVGPAGPR 1565

Query: 282  SAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIAD 341
             A  +G     GP      PG V  G P P+  P   G              +G+   A 
Sbjct: 1566 GA--TGVQGERGP------PGLVLPGDPGPKGDPGDRG-------------PIGLTGRAG 1604

Query: 342  LSTDPTELEERALEVAGPDGQASAISPASPRRKAADGGHR--RALPGCTSLTGET----- 394
               D     E+     G  G+     P  PR +  + G +     PG   L G+      
Sbjct: 1605 PPGDSGPPGEK-----GDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGL 1659

Query: 395  ------TGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGAGDSGHASP-----DTG 443
                   G  GE G  G P  D   G       +PGS       G+ G   P     DTG
Sbjct: 1660 RGAPGVRGPVGEKGDQGDPGEDGRNG-------SPGSSGPKGDRGEPGPPGPPGRLVDTG 1712

Query: 444  PCVNQKQEPGPAQEEAELG--------GQNLERDLEGFRVSP 477
            P   +K EPG   +E   G        G   ER +EGFR  P
Sbjct: 1713 PGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPP 1754



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 70/241 (29%), Positives = 88/241 (36%), Gaps = 29/241 (12%)

Query: 187  GDSQPD----DPPDRGTGLSASQRASQDHLSEQGADDSKPETDRVPGDGGQK--EHLPSI 240
            GDS P     DP   G       R     + E+G D+  P    +PG  G++     P +
Sbjct: 1607 GDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKG-DEGPPGDPGLPGKAGERGLRGAPGV 1665

Query: 241  DSE-GEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPASAPTSGPAPGLGPASWCL 299
                GEK D+G P E G   + G+  P G + E  G P  P     +GP      A    
Sbjct: 1666 RGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGE-PGPPGPPGRLVDTGPG-----AREKG 1719

Query: 300  EPGSVAQGSP-DPQQTPSRMGREGE-------GTHSSLGCSSLGMVVIADLSTDPTELEE 351
            EPG   Q  P  P+  P   G  GE       G     G   +           P  L+ 
Sbjct: 1720 EPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDG 1779

Query: 352  RALEVAGPDGQASAISPASPRRKAADGGH--RRALPGCTSLTGETTGESGEAGQDGKPPG 409
            R    +G DG+  A  P+ P   A   G   R  LPG     G   G SG  G  GKP  
Sbjct: 1780 R----SGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQG-LPGPSGPPGLPGKPGE 1834

Query: 410  D 410
            D
Sbjct: 1835 D 1835



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 71/260 (27%), Positives = 88/260 (33%), Gaps = 49/260 (18%)

Query: 228  PGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPASAPTSG 287
            PG  G K    S   +G K DRG P   G +   G   P G     DG P  P     +G
Sbjct: 2110 PGLKGAKGEPGSNGDQGPKGDRGVP---GIKGDRGEPGPRGQ----DGNPGLPGERGMAG 2162

Query: 288  P--APGL-GPASWCLEPGSV-AQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIADLS 343
            P   PGL GP      PG V   G P P   P   G  G    S              L 
Sbjct: 2163 PEGKPGLQGPRG---PPGPVGGHGDPGPPGAPGLAGPAGPQGPSG-------------LK 2206

Query: 344  TDPTELEERALEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGE--------TT 395
             +P E       + GP G      P  P       G    LPG    TG+         +
Sbjct: 2207 GEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQG-SPGLPGQVGETGKPGAPGRDGAS 2265

Query: 396  GESGEAGQDGKPPGDVL---VGPTASLALAPGSGESMMG----AGDSGHASPDTGPCVNQ 448
            G+ G+ G  G P    L   VGP          G++++G     G+ G      G  V +
Sbjct: 2266 GKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGE 2325

Query: 449  ------KQEPGPAQEEAELG 462
                  +  PGP  E+ E G
Sbjct: 2326 PGAKGDRGLPGPRGEKGEAG 2345



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 116/459 (25%), Positives = 145/459 (31%), Gaps = 103/459 (22%)

Query: 46   PEGKLGPVPSTQQHGEE--PGKAVSSSPDE---------ETGSPCRLLRQPEKE---PAP 91
            P G  GPV      G    PG A  + P           ETG P R L  P      P P
Sbjct: 2172 PRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGP 2231

Query: 92   LPPS-----QNSFGR--FVPQFAKSRKTVTRKEEMKDEDRGSGAFSLETIAESSAQSPGC 144
              PS     Q S G    V +  K           KD DRGS               PG 
Sbjct: 2232 PGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGV------------PGS 2279

Query: 145  QLLVETLGVPLQEATELGDPTQADSARPEQSSQSPVQAVPG--SGD--SQPDDPPDRGTG 200
              L   +G P  E    G P QA    P    +   +  PG  +GD   +P    DRG  
Sbjct: 2280 PGLPGPVG-PKGEPGPTGAPGQAVVGLPGAKGE---KGAPGGLAGDLVGEPGAKGDRGLP 2335

Query: 201  LSASQRASQDHLSEQGADDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRT 260
                ++       E G           PG+ GQK               GAP   G +  
Sbjct: 2336 GPRGEKGEAGRAGEPGD----------PGEDGQK---------------GAPGPKGFKGD 2370

Query: 261  AGAGLPGGPQEEGD-------GVPCTPASAPTSGPAPGLGPASWCLEPGSVAQ----GSP 309
             G G+PG P   G        G+P  P +    G     GP     +PG   +    G P
Sbjct: 2371 PGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPP 2430

Query: 310  DPQQTPSRMGREG-EGTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQASAISP 368
              +  P  +G  G  G+    G S L             +  +  + + GP G+      
Sbjct: 2431 GREGIPGPLGPPGPPGSVGPPGASGL-----------KGDKGDPGVGLPGPRGER----- 2474

Query: 369  ASPRRKAADGGHRRALPGCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLALAPGSGES 428
              P  +  DG  R    G   LTG   G  GE G+ G      L G     A+  G    
Sbjct: 2475 GEPGIRGEDG--RPGQEGPRGLTG-PPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGP 2531

Query: 429  MMGAGDSGHASP-----DTGPCVNQKQEPGPAQEEAELG 462
                GD G   P     D GP      +PG    + E G
Sbjct: 2532 RGAKGDMGERGPRGLDGDKGP-RGDNGDPGDKGSKGEPG 2569



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 81/346 (23%), Positives = 111/346 (32%), Gaps = 49/346 (14%)

Query: 184  PGSGDSQPDDPPDRGTGLSASQRASQDHLSEQGA-----DDSKPETDRVPGDGGQKEHLP 238
            PG   S+  +P D+G+      R       + GA     D   P  D VPG  G+K  + 
Sbjct: 2559 PGDKGSK-GEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVG 2617

Query: 239  SIDSEGEKPDRGAPQEGGAQRTAG----AGLPGGPQEEGD----GVPCTPASAPTSGPAP 290
             +   G K +RG     G     G    AG PG P   G     G P  P  +   G   
Sbjct: 2618 FMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEG 2677

Query: 291  GLGPASWCLEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIADLSTDPTELE 350
             +GP     + G   Q  P   Q     G +GE     +G              D +   
Sbjct: 2678 LIGPKG---DRGFDGQPGPKGDQ-----GEKGERGTPGIGGFP------GPSGNDGS--- 2720

Query: 351  ERALEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGE--TTGESGEAGQDGKPP 408
                  AGP G   ++ P  P       G R   P    + G     G  GE G+ G+P 
Sbjct: 2721 ------AGPPGPPGSVGPRGPEGLQGQKGERG--PPGERVVGAPGVPGAPGERGEQGRPG 2772

Query: 409  GDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELGGQ---- 464
                 G     AL        +    S H +   G  +     P P+      G Q    
Sbjct: 2773 PAGPRGEKGEAALTEDDIRGFVRQEMSQHCACQ-GQFIASGSRPLPSYAADTAGSQLHAV 2831

Query: 465  ---NLERDLEGFRVSPQASVVLEHREIADDPLQEPGAQQGIPDTTS 507
                +    E  RV P+     E+ E + +  Q+P A     D  S
Sbjct: 2832 PVLRVSHAEEEERVPPEDDEYSEYSEYSVEEYQDPEAPWDSDDPCS 2877



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 82/328 (25%), Positives = 106/328 (32%), Gaps = 49/328 (14%)

Query: 212  LSEQGADDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQE 271
            L+ +  +   P  D   G+ G          +G K +RGAP   G Q     GLPG    
Sbjct: 1840 LNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQ--GPPGLPGPVGP 1897

Query: 272  EGDGVPCTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGC 331
             G G P  P     +GP    G             GS   Q  P   G  GE        
Sbjct: 1898 PGQGFPGVPGG---TGPKGDRGET-----------GSKGEQGLPGERGLRGEP------- 1936

Query: 332  SSLGMVVIADLSTDPTELEERALE--VAGPDGQASAISPASPRRKAADGGHRRALP---- 385
               G V   D   +   ++  AL   V   D  + +  P   RR+   G      P    
Sbjct: 1937 ---GSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKE 1993

Query: 386  GCTSLTGE--TTGESGEAGQDGKPPGDVL--VGPTASLALAPGSGESMMGAGDSGHASPD 441
            G     GE    G+ G+ G  G PPG  L   GP     LA   G+     G  G   P 
Sbjct: 1994 GPIGFPGERGLKGDRGDPGPQG-PPGLALGERGPPGPSGLAGEPGK----PGIPG--LPG 2046

Query: 442  TGPCVNQKQEPGPAQEEAELG--GQNLERDLEGFRVSPQASVVLEHREIADDPLQEPGAQ 499
                V +   PG   E  E G  G+       G   +P        +   D+P      +
Sbjct: 2047 RAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGE 2106

Query: 500  QGIPDTTSELAGQRDHLPHSADQGTWAD 527
            QG P     L G +     + DQG   D
Sbjct: 2107 QGPPG----LKGAKGEPGSNGDQGPKGD 2130


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 67/238 (28%), Positives = 87/238 (36%), Gaps = 32/238 (13%)

Query: 229  GDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGD-GVPCTPASAPTSG 287
            GD G+K  +  I  +G + D G P  G   +   AG PG P  +GD G+  TP +    G
Sbjct: 951  GDQGEKGQIGPIGEKGSRGDPGTP--GVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPG 1008

Query: 288  PAPGLGPASWCLEPGSV-AQGSPDPQQTPSRMGREG-EGTHSSLGCSSLGMVVIADLSTD 345
            P   +G       PG     G P PQ +P   G +G +G     G   +G+  +     D
Sbjct: 1009 PKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGD 1068

Query: 346  PTELEERALEVAGPDGQASAISPASPRRKAADGG-HRRALPGCTSLTGE--------TTG 396
                            Q  A  P SP  K   G      +PG   L G         + G
Sbjct: 1069 ----------------QGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPG 1112

Query: 397  ESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGP-CVNQKQEPG 453
              GE G  G P  D + G      L PG+      AG  G    D  P    +K EPG
Sbjct: 1113 LPGEKGDKGLPGLDGIPGVKGEAGL-PGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPG 1169



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 77/300 (25%), Positives = 104/300 (34%), Gaps = 65/300 (21%)

Query: 184 PGS-GDSQPDDPPDRGTGLSASQRASQDHLSEQGADD---SKPETDRV---PGDGGQKEH 236
           PGS GD+ P  PP  G       +         G+      K E  ++   PG  G +  
Sbjct: 594 PGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGL 653

Query: 237 LPSIDSEGEKPDRG---------APQEGGAQRTAGAGLPGGPQEEG-DGVPCTPASAPTS 286
             S    G + DRG          P E GA    G G PG P  +G DG+P         
Sbjct: 654 PGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLP--------- 704

Query: 287 GPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSSL-GMVVIADLSTD 345
                +GP      PG+   G P     P   G +G+     +G   L G+  +  +   
Sbjct: 705 ---GDMGP------PGT--PGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGT 753

Query: 346 PTELEERALEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGETTGESGEAGQDG 405
           P   E+ ++ V G  G+  AI P                PG   + GE  G  G  G  G
Sbjct: 754 PG--EKGSIGVPGVPGEHGAIGP----------------PGLQGIRGE-PGPPGLPGSVG 794

Query: 406 KP--PGDVLVGPTASLALAPGSGESMMG-AGDSGHASPDTGPCVNQKQEPGPAQEEAELG 462
            P  PG   +GP    A  P  G+   G +G  G       P       PGP  ++   G
Sbjct: 795 SPGVPG---IGPPG--ARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQG 849



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 67/235 (28%), Positives = 83/235 (35%), Gaps = 33/235 (14%)

Query: 243 EGEKPDRGAPQEGGAQRTAGAGLPGGPQ----EEGD-GVPCTPASAPTSGPAPGLGPASW 297
           +G+K +RG P   G     G   P GPQ    ++GD G P  P +  T GP    G    
Sbjct: 45  KGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGN 104

Query: 298 CLEPGSVAQ-GSPDPQQTPSRMGREGEGTHSSLGCSSL-------GMVVIADLSTDPTEL 349
              PG   Q G P P   P   G +GE     LG   L       G   +  +  DP E+
Sbjct: 105 PGLPGIPGQDGPPGPPGIPGCNGTKGE--RGPLGPPGLPGFAGNPGPPGLPGMKGDPGEI 162

Query: 350 EERALEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGET--TGESGEAGQDGKP 407
                 V G   +     P  P      G     LPG     G    TG  G  G  G P
Sbjct: 163 ---LGHVPGMLLKGERGFPGIPGTPGPPG-----LPGLQGPVGPPGFTGPPGPPGPPG-P 213

Query: 408 PGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELG 462
           PG+        L+     G+     GD G + P   P   Q QE G    + E G
Sbjct: 214 PGE---KGQMGLSFQGPKGDK----GDQGVSGPPGVPGQAQVQEKGDFATKGEKG 261



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 82/352 (23%), Positives = 108/352 (30%), Gaps = 72/352 (20%)

Query: 172  PEQSSQSPVQAVPGSGDSQPDDPPDRGTGLSASQRASQDHLSEQGADDSKPETDRVPGDG 231
            P +  +     +PG     P  P  +G+  S     S     E+G D   P  D +PG  
Sbjct: 1078 PGEKGEKGSIGIPG----MPGSPGLKGSPGSVGYPGSPGLPGEKG-DKGLPGLDGIPGVK 1132

Query: 232  GQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGA---------GLPGGPQEEGDGVPCTPAS 282
            G+     +    G    +G P   G   +AG          G PG P  +GD        
Sbjct: 1133 GEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVG 1192

Query: 283  APTSGPAPGLGPASWCLEPGSVAQ----GSPDPQQTPSRMGREGEGTHSSLGCSSLGMVV 338
             P    +PG+        PGS  +    G P PQ  P   G  G  T    G        
Sbjct: 1193 FPGLAGSPGI--------PGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKG-------- 1236

Query: 339  IADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGETTGES 398
                               GP GQ     P  P      G     LPG         G  
Sbjct: 1237 -----------------DRGPQGQPGL--PGLPGPMGPPG-----LPG-------IDGVK 1265

Query: 399  GEAGQDGKPPGDVLVGPTASLAL--APGSGESMMGAGDSGHASPDTGP-CVNQKQEPGPA 455
            G+ G  G P    + GP         PG G S    G  G   P   P     K  PG  
Sbjct: 1266 GDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQ 1325

Query: 456  QEEAELGGQNL--ERDLEGFRVSPQASVVLEHREIADDPLQEPGAQ--QGIP 503
              + + G Q +   + L G    P    +++       P   PG +  QG+P
Sbjct: 1326 GIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLP 1377



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 74/264 (28%), Positives = 83/264 (31%), Gaps = 71/264 (26%)

Query: 227 VPGDGGQKEHLPSIDSE-GEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDG---------V 276
           VPG  G     P    E GEK DRG P       +   GLPG P   G           V
Sbjct: 377 VPGQAGA----PGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIV 432

Query: 277 PCTPASAPTSGPAPGL-GPASWCLEPGSVAQ--------------GSPDPQQTPSRMGRE 321
            C P      GP PG+ G   +  E G   Q              G P PQ  P  +G  
Sbjct: 433 ECQPGPPGDQGP-PGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFP 491

Query: 322 GE-GTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADGGH 380
           G+ G     G                    +    V GP G    I    P  K   G  
Sbjct: 492 GQPGAKGDRGLPG----------------RDGVAGVPGPQGTPGLI--GQPGAKGEPGEF 533

Query: 381 RRAL--------PGCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLALAPGSGE--SMM 430
              L        PG     G  TG +G  G+DG P    L GP  S       GE     
Sbjct: 534 YFDLRLKGDKGDPGFPGQPG-MTGRAGSPGRDGHPG---LPGPKGSPGSVGLKGERGPPG 589

Query: 431 GAGDSGHASPDTGPCVNQKQEPGP 454
           G G  G +  DTGP       PGP
Sbjct: 590 GVGFPG-SRGDTGP-------PGP 605



 Score = 38.1 bits (87), Expect = 0.025
 Identities = 83/332 (25%), Positives = 106/332 (31%), Gaps = 73/332 (21%)

Query: 154 PLQEATELGDPTQADSARPEQSSQSPVQAVPGSGDSQPDDPPDRGTGLSASQRASQDHLS 213
           P  E  ++G   Q           S    VPG    Q     ++G   +  ++  +    
Sbjct: 213 PPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQ-----EKGDFATKGEKGQKGEPG 267

Query: 214 EQG-------ADDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLP 266
            QG        +  KP     PG  G K         GEK   G P E G     G   P
Sbjct: 268 FQGMPGVGEKGEPGKPGPRGKPGKDGDK---------GEKGSPGFPGEPGYPGLIGRQGP 318

Query: 267 GGPQEEGDGVPCTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGEGTH 326
            G + E  G P  P     +GP    G   +   PG   +G P P+  P   G+ G    
Sbjct: 319 QGEKGEA-GPPGPPGIVIGTGPLGEKGERGYPGTPG--PRGEPGPKGFPGLPGQPGPP-- 373

Query: 327 SSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADGGHRRALPG 386
                   G+ V                      GQA A  P  P  +   G   R  PG
Sbjct: 374 --------GLPV---------------------PGQAGA--PGFPGERGEKGD--RGFPG 400

Query: 387 CTSLTGETTGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMG-AGDSGHASPDTGPC 445
            TSL G  +G  G  G  G P      GP        G  E   G  GD G   P   P 
Sbjct: 401 -TSLPG-PSGRDGLPGPPGSP------GPPGQPGYTNGIVECQPGPPGDQG---PPGIP- 448

Query: 446 VNQKQEPGPAQEEAELGGQNLERDLEGFRVSP 477
             Q    G   E+ + G   L  D++G+R  P
Sbjct: 449 -GQPGFIGEIGEKGQKGESCLICDIDGYRGPP 479



 Score = 34.7 bits (78), Expect = 0.28
 Identities = 56/192 (29%), Positives = 63/192 (32%), Gaps = 24/192 (12%)

Query: 228 PGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGA----GLPGG---PQEEGDGVPCTP 280
           PG  GQ        S G     G P   G+  + G     G PGG   P   GD  P  P
Sbjct: 546 PGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGP 605

Query: 281 ASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRM----GREG-EGTHSSLGCSSLG 335
                +GP    G A +   PGS   G P P+  P ++    G  G EG   S G     
Sbjct: 606 PGYGPAGPIGDKGQAGFPGGPGS--PGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPG-- 661

Query: 336 MVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGETT 395
                D     T          G  GQ     P  P  K  DG     LPG     G T 
Sbjct: 662 --PQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDG-----LPGDMGPPG-TP 713

Query: 396 GESGEAGQDGKP 407
           G  G  G  G P
Sbjct: 714 GRPGFNGLPGNP 725



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 58/231 (25%), Positives = 77/231 (33%), Gaps = 30/231 (12%)

Query: 228 PGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPASAPTSG 287
           PG  G+K  +  +  +G K D+G     G       G+PG  Q +  G         T G
Sbjct: 211 PGPPGEKGQM-GLSFQGPKGDKGDQGVSGPP-----GVPGQAQVQEKG------DFATKG 258

Query: 288 PAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGE-GTHSSLGC-SSLGMVVIADLSTD 345
                G   +   PG   +G P       + G++G+ G   S G     G   +      
Sbjct: 259 EKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGP 318

Query: 346 PTELEERALEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGE--TTGESGEAGQ 403
             E  E     AGP G    +    P  +  + G+    PG     GE    G  G  GQ
Sbjct: 319 QGEKGE-----AGPPGPPGIVIGTGPLGEKGERGY----PGTPGPRGEPGPKGFPGLPGQ 369

Query: 404 DGKPPGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGP 454
            G PPG     P    A APG        GD G           +   PGP
Sbjct: 370 PG-PPG----LPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGP 415


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 91/303 (30%), Positives = 109/303 (35%), Gaps = 56/303 (18%)

Query: 179  PVQAVPGSGDSQPDDPPDRGTGLSASQRASQDHLSEQGADDSKPETDRVPGDGGQKEHLP 238
            PV A+   G+  P  PP  G   S  +R         G    +P     PG  G+K    
Sbjct: 1067 PVGALGLKGNEGPPGPP--GPAGSPGERGPAGAAGPIGIP-GRPGPQGPPGPAGEK---- 1119

Query: 239  SIDSEGEKPDRGAPQEGGAQRTAG----AGLPGGPQEEGD-------GVPCTPASAPTSG 287
               + GEK  +G     G Q   G    AG  G P E+GD       G   +       G
Sbjct: 1120 --GAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQG 1177

Query: 288  PAPGLGPASWCLEPG-SVAQGSPDPQQTPSRMGREG-EGTHSSLGCSSLGMVVIADLSTD 345
            P    GP     +PG S A G P P+      G++G EG     G    G V +  L   
Sbjct: 1178 PPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPG--PPGPVGLQGLPGP 1235

Query: 346  PTELEERALEVAGPDGQASAISPASPR----RKAADGGHRRALPGCTSLTGETTGESGEA 401
            P E  E      G  GQ     P  PR       ADG   +  PG     G   GE GE 
Sbjct: 1236 PGEKGE-----TGDVGQMGPPGPPGPRGPSGAPGADG--PQGPPGGIGNPG-AVGEKGEP 1287

Query: 402  GQDGKP--PGDVLVGPTASLALAPGSGESMMGAGDSGHASP--------DTGPCVNQKQE 451
            G+ G+P  PG+   GP          GES    G SG A P        D GP    K  
Sbjct: 1288 GEAGEPGLPGE--GGPPGPKGERGEKGES----GPSGAAGPPGPKGPPGDDGP----KGS 1337

Query: 452  PGP 454
            PGP
Sbjct: 1338 PGP 1340



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 83/295 (28%), Positives = 104/295 (35%), Gaps = 68/295 (23%)

Query: 216  GADDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAG------------- 262
            G D  K E     G+ GQK       S+G+K ++G P   G Q   G             
Sbjct: 1153 GEDGDKGEI----GEPGQK------GSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGP 1202

Query: 263  ---------------AGLPGGPQEEG-DGVPCTPASAPTSGPAPGLGPASWCLEPG---- 302
                            G PG P   G  G+P  P     +G    +GP      PG    
Sbjct: 1203 RGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPG---PPGPRGP 1259

Query: 303  SVAQGSPDPQQTPSRMGREGE-GTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDG 361
            S A G+  PQ  P  +G  G  G     G    G   +      P    ER  +  G  G
Sbjct: 1260 SGAPGADGPQGPPGGIGNPGAVGEKGEPG--EAGEPGLPGEGGPPGPKGERGEK--GESG 1315

Query: 362  QASAISPASPRRKAADGGHRRALPGCTSLTGE--TTGESGEAGQDGKPPGDVLVGPTASL 419
             + A  P  P+    D G + + PG     G+    GE G AGQDG PPGD   G     
Sbjct: 1316 PSGAAGPPGPKGPPGDDGPKGS-PGPVGFPGDPGPPGEPGPAGQDG-PPGD--KGDDGE- 1370

Query: 420  ALAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELG--GQNLERDLEG 472
               PG   S    G+ G + P       ++  PGPA  E   G  G   E  LEG
Sbjct: 1371 ---PGQTGSPGPTGEPGPSGPP-----GKRGPPGPAGPEGRQGEKGAKGEAGLEG 1417



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 105/449 (23%), Positives = 147/449 (32%), Gaps = 95/449 (21%)

Query: 44  EEPEGKLGPVPSTQQHGEEPGKAVSSSPDEETGSPCRLLRQPEKEPAPLPPSQNSFGRFV 103
           E+PE  LG  P+  +   E  K  +  P+E T +P         E AP+P +    G   
Sbjct: 281 EDPED-LGKEPTPSKKPVEAAKETTEVPEELTPTP--------TEAAPMPETSEGAG--- 328

Query: 104 PQFAKSRKTVTRKEEMKDEDRGSGAFSLETIAESSAQSPGCQLLVETLGVPLQEATELGD 163
                           K+ED G G +      +    SP   L   T G         G+
Sbjct: 329 ----------------KEEDVGIGDYDYVPSEDYYTPSPYDDL---TYGE--------GE 361

Query: 164 PTQADSARPEQSSQSPVQAVPGSGDSQPDDPPDRGTG------LSASQRASQDHLSEQGA 217
                   P   ++ P      S  S P  PP  G           + R   ++  +   
Sbjct: 362 ENPDQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYDPYY 421

Query: 218 DDSKPETDRVPGDGGQKEHLPS--IDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDG 275
           D +   ++  PG    ++ +        GEK  +G P    A    G  + G P  EG  
Sbjct: 422 DPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEP----AIIEPGMLIEGPPGPEG-- 475

Query: 276 VPCTPASAPTSGPAPGLGPASWCLEPGS----------VAQGSPDPQQT----PSRMGRE 321
               PA  P  GP   +GP     +PG            A G P P  T    P R G  
Sbjct: 476 ----PAGLP--GPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGG 529

Query: 322 GEGTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADGGHR 381
           G+         S G +V A  S     L++  L + GP G         P      GG  
Sbjct: 530 GD-------AGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGG-L 581

Query: 382 RALPGCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLALAPGSG-------ESMMG-AG 433
           +  PG     G   G  G  G  GKP      G   +  +   +G       + + G  G
Sbjct: 582 KGEPGDVGPQG-PRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPG 640

Query: 434 DSGHASPDTGPCVNQKQEPGPAQEEAELG 462
           + GH   D GP       PGP  ++ E G
Sbjct: 641 EKGHRG-DPGP----SGPPGPPGDDGERG 664



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 73/264 (27%), Positives = 93/264 (35%), Gaps = 46/264 (17%)

Query: 228  PGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQ----EEGDGVPCTPASA 283
            PG  G +     I + G   ++G P E G     G G P GP+    E+G+  P   A  
Sbjct: 1263 PGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGP 1322

Query: 284  P-TSGPAPGLGPASWCLEPGSVA-QGSPDPQQTPSRMGREG----EGTHSSLGCSSLGMV 337
            P   GP    GP      PG V   G P P   P   G++G    +G     G +     
Sbjct: 1323 PGPKGPPGDDGPKG---SPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTG---- 1375

Query: 338  VIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGE--TT 395
                 S  PT         +GP G+     PA P  +  + G +    G   L G    T
Sbjct: 1376 -----SPGPT----GEPGPSGPPGKRGPPGPAGPEGRQGEKGAK----GEAGLEGPPGKT 1422

Query: 396  GESGEAGQDGKPPGDVL---VGPTASLAL----APGSGESMMGAGDSGHASPDTGPCVNQ 448
            G  G  G  GKP  D L    GP     L     P      MG         D+GP   +
Sbjct: 1423 GPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGP-KGE 1481

Query: 449  KQEP------GPAQEEAELGGQNL 466
            K  P      GP  E+ E G + L
Sbjct: 1482 KGHPGLIGLIGPPGEQGEKGDRGL 1505



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 83/295 (28%), Positives = 103/295 (34%), Gaps = 39/295 (13%)

Query: 184  PGSGDSQPDDPPDRGTGLSASQRASQDHLSEQGADDSKPETDRVPGDGGQKEHLPSIDSE 243
            PG    +P  P + G      +R  +      GA    P     PGD G K     +   
Sbjct: 1287 PGEA-GEPGLPGEGGPPGPKGERGEKGESGPSGAA-GPPGPKGPPGDDGPKGSPGPVGFP 1344

Query: 244  GEKPDRGAPQEGGAQRTAGAGLPGGPQEEGD-GVPC-TPASAPTSGPAPGLGPASWCLEP 301
            G   D G P E G      AG  G P ++GD G P  T +  PT  P P  GP      P
Sbjct: 1345 G---DPGPPGEPGP-----AGQDGPPGDKGDDGEPGQTGSPGPTGEPGPS-GP------P 1389

Query: 302  GSVAQGSPDPQQTPSRMGREG-------EGTHSSLGC----SSLGMVVIADLSTDPTELE 350
            G   +G P P     R G +G       EG     G      + G      L   P  + 
Sbjct: 1390 GK--RGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVG 1447

Query: 351  ERALEVA-GPDGQASAISPASPRRKAADGGHR--RALPGCTSLTGETTGESGEAGQDGKP 407
            E+ L  + GPDG    + P        D G +  +  PG   L G   GE GE G  G P
Sbjct: 1448 EQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPP-GEQGEKGDRGLP 1506

Query: 408  PGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELG 462
                  GP     +   SG  +   G  G   P  GP    K   GP   + E G
Sbjct: 1507 GPQGSSGPKGEQGITGPSG-PIGPPGPPGLPGP-PGP-KGAKGSSGPTGPKGEAG 1558



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 113/447 (25%), Positives = 144/447 (32%), Gaps = 87/447 (19%)

Query: 46   PEGKLGPVPSTQQHGEEPGKAVSSSPDEETGSPCRLLRQPEKEPAPLPPSQNSFGRFVPQ 105
            P+G +GP P  +    +PG       D   G P +     EK     P  Q   G   P+
Sbjct: 734  PQGAIGP-PGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPR 792

Query: 106  FAKSRKTVTRKEEMKDEDRGSGAFSLETIAESSAQSPGCQLLVETLGVPLQEATELGDPT 165
              K    +   +  K E +G   F            PG +  +   G    +  E+G P 
Sbjct: 793  GVKGADGIRGLKGTKGE-KGEDGF------------PGFKGDMGIKG----DRGEIGPP- 834

Query: 166  QADSARPEQSSQSPVQAVPGSGDSQPDDPPDRGTGLSA----------SQRASQDHLSEQ 215
                 R E   + P      +GD  P  PP     L              + S       
Sbjct: 835  ---GPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFP 891

Query: 216  GADDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQ-EEGD 274
            GA+  K      PG  G +         GE+  RG   + G +  +G   P GP  E G 
Sbjct: 892  GANGEKGGRG-TPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGP 950

Query: 275  GVPCTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGE-GTHSSLGCSS 333
              P      PT  P P  GP            G P     P   G+ GE G     G   
Sbjct: 951  NGP----QGPTGFPGP-KGP-----------PGPPGKDGLPGHPGQRGETGFQGKTGPPG 994

Query: 334  LGMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGE 393
               VV     T  T          GP G+     P  P  +       + LPG     G 
Sbjct: 995  PPGVVGPQGPTGET----------GPMGERGHPGPPGPPGE-------QGLPGLAGKEG- 1036

Query: 394  TTGESGEA---GQDGKP-----PGD-VLVGPTASLAL--------APGSGESMMGAGDSG 436
            T G+ G A   G+DG P     PGD  L GP  +L L         PG   S    G +G
Sbjct: 1037 TKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAG 1096

Query: 437  HASPDTGPCVNQKQ-EPGPAQEEAELG 462
             A P   P     Q  PGPA E+   G
Sbjct: 1097 AAGPIGIPGRPGPQGPPGPAGEKGAPG 1123



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 121/485 (24%), Positives = 149/485 (30%), Gaps = 98/485 (20%)

Query: 52  PVPSTQQH-GEEPGKAVSS-----SPDEETGSPCRLLRQPEKEPAPLPPSQNSFGRFVPQ 105
           P+P T +  G+E    +       S D  T SP   L   E E  P  P+    G  +P 
Sbjct: 319 PMPETSEGAGKEEDVGIGDYDYVPSEDYYTPSPYDDLTYGEGEENPDQPTDPGAGAEIPT 378

Query: 106 FAKSRKTVTRKEEMKDE--DRGSGAFSLETI---------------AESSAQSPGC---- 144
                   +       E  D   G F+ ETI               +  S   PG     
Sbjct: 379 STADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDPTSSPSEIGPGMPANQ 438

Query: 145 QLLVETLGVPLQEATELGDPTQADSARPEQSSQSPVQAVPGSGDSQPDDPPDRGTGLSAS 204
             + E +G P  E  + G+P   +     +    P       G +    PP  GT     
Sbjct: 439 DTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGP------EGPAGLPGPP--GTMGPTG 490

Query: 205 QRASQDHLSEQGADDSKPETDRVPGDGGQKEHLP----SIDSEGEKPDRGAPQEGGAQ-- 258
           Q          G     P  D +PG  G    LP         G K    + QE  AQ  
Sbjct: 491 QVGDPGERGPPGRP-GLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAI 549

Query: 259 ----RTAGAGLPGGPQEEGDGVPCTPASAPTSGPAPGLGPASWCLEPGSVA-------QG 307
               R A  G P GP     G P  P   P SG   G        EPG V        QG
Sbjct: 550 LQQARLALRG-PAGPMGL-TGRP-GPVGPPGSGGLKG--------EPGDVGPQGPRGVQG 598

Query: 308 SPDPQQTPSRMGREG-EGTHSSLGCSS-LGMVVIADLSTDPTELEERALE-------VAG 358
            P P   P R GR G +G     G +   G      L+  P E   R            G
Sbjct: 599 PPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPG 658

Query: 359 PDGQASAISPASPRRKAADGGHRRAL-----------PGCTSLTGET--------TGESG 399
            DG+        PR    + G R  L           PG T + G+          GE G
Sbjct: 659 DDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPG 718

Query: 400 EAGQDGKPPGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQEEA 459
             GQ G P    L GP  ++   PG    +   G  G    D  P       PG      
Sbjct: 719 PPGQQGNPGAQGLPGPQGAIG-PPGEKGPLGKPGLPGMPGADGPP-----GHPGKEGPPG 772

Query: 460 ELGGQ 464
           E GGQ
Sbjct: 773 EKGGQ 777


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 75/275 (27%), Positives = 103/275 (37%), Gaps = 50/275 (18%)

Query: 212 LSEQGADDSK--PETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGA-GLPGG 268
           + E+GA  ++  P +D +PG  G +     + S G K  +G P   G     GA GL G 
Sbjct: 518 VGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGN 577

Query: 269 PQEEGDGVPCTPASAPTSGPAPGLGPASWCL--EPGSVAQGSPDPQQTPSRMGREGEGTH 326
           P  +G      P  AP     PG  P S  +  +PGS+  G P P+ +    G+ GE  +
Sbjct: 578 PGVQGPEGKLGPLGAPGEDGRPG-PPGSIGIRGQPGSM--GLPGPKGSSGDPGKPGEAGN 634

Query: 327 SSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADGGHRRALPG 386
           + +                            G DG+     P  P   A + G  +  PG
Sbjct: 635 AGV---------------------PGQRGAPGKDGEVGPSGPVGPPGLAGERG-EQGPPG 672

Query: 387 CTSLTGETTGESGEAGQDGKP-----PGDV-LVGPTASLALAPGSGE----SMMG----A 432
            T   G   G  G  G+ GKP     PGD   VGP          GE     + G     
Sbjct: 673 PTGFQG-LPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEK 731

Query: 433 GDSGHASPDTGPCVNQKQEPGPAQEEAELGGQNLE 467
           G +G   PD GP    K  PGP+    + G   L+
Sbjct: 732 GMAGGHGPD-GP----KGSPGPSGTPGDTGPPGLQ 761



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 96/357 (26%), Positives = 118/357 (33%), Gaps = 83/357 (23%)

Query: 172  PEQSSQSPVQAVPGSGDS--------QPDDPPDRG----TGLSASQRASQDHLSEQGADD 219
            P +  +   Q VPG   +        +  +P +RG    TGL   +  +  H    G D 
Sbjct: 686  PGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGH----GPDG 741

Query: 220  SK--PETDRVPGDGGQK--EHLPS----IDSEGEKPDRGAPQEGGAQRTAG----AGLPG 267
             K  P     PGD G    + +P       + G K DRG   E GA+ TAG     GLPG
Sbjct: 742  PKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPG 801

Query: 268  GPQEEGDGVPCTPASAPTSGPAPGLGPASWCLEPGSVAQGSP----------DPQQTPSR 317
                 G   P      P  GP   +GP      PGS  +  P           P   P  
Sbjct: 802  PLGPPGPAGPTGEKGEP--GPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGV 859

Query: 318  MGREGE-------------------GTHSSLGCSSLGMVVIADLSTDPTELEERALEVAG 358
             G  GE                   G H   G   L            T     A  V G
Sbjct: 860  KGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRV-G 918

Query: 359  PDGQASAISPASPRRKAADGG--HRRALPGCTSLTGET--------TGESGEAGQDGKPP 408
            P G A A  PA P  +    G    R  PG     G+          G+ G+ G+DG+P 
Sbjct: 919  PPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPG 978

Query: 409  GDVLVGPTAS-----LALAPGS-GESMM-----GAGDSGHASPDTGPCVNQKQEPGP 454
             D   GP  +     +   PG  GE  M      AG  G   P TG     K  PGP
Sbjct: 979  PDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGP-TG-ATGDKGPPGP 1033



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 98/387 (25%), Positives = 125/387 (32%), Gaps = 81/387 (20%)

Query: 158  ATELGDPTQADSARP-----EQSSQSP--VQAVPGS----GDSQPDDPPDRGTGLSASQR 206
            A  +G P  A +  P     E   + P  ++  PGS    GD  P  PP  G G      
Sbjct: 914  AGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPG-GPGDKGDP- 971

Query: 207  ASQDHLSEQGADDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAG-AGL 265
                       +D +P  D  PG  G       +   G++ +RG P   G   T G  G 
Sbjct: 972  ----------GEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGP 1021

Query: 266  PGGPQEEGDGVPCTP--ASAPTSGPAPGLGPASWCLEPGSVA-------QGSPDPQQTPS 316
             G   ++G   P  P  ++ P   P P  GPA     PG          +G P P   P 
Sbjct: 1022 TGATGDKGPPGPVGPPGSNGPVGEPGPE-GPAGNDGTPGRDGAVGERGDRGDPGPAGLPG 1080

Query: 317  RMGREGEGTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAA 376
              G    GT   +G         A    DP       +   G  G+     P  PR    
Sbjct: 1081 SQG--APGTPGPVGAPG-----DAGQRGDPG--SRGPIGPPGRAGKRGLPGPQGPRGDKG 1131

Query: 377  DGGHR--------RALPGCTSLTGE--TTGESGEAGQDGK-----PPGDVLVGPTASLA- 420
            D G R        R   G   L G     GE G AG  G      PPG   VGP+     
Sbjct: 1132 DHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGP--VGPSGKEGN 1189

Query: 421  ---LAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELGGQNLERDLEGFRVSP 477
               L P     + G+   G A P+  P      EPGP                 G   + 
Sbjct: 1190 PGPLGPIGPPGVRGS--VGEAGPEGPP-----GEPGPPGPPGP----------PGHLTAA 1232

Query: 478  QASVVLEHREIADDPLQEPGAQQGIPD 504
               ++  + E   DPL E    Q  PD
Sbjct: 1233 LGDIMGHYDESMPDPLPEFTEDQAAPD 1259



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 73/287 (25%), Positives = 103/287 (35%), Gaps = 33/287 (11%)

Query: 187 GDSQPDDPPDR-GTGLSASQRASQDHLSEQGADDSK--PETDRVPGDGGQKEHLPSIDSE 243
           G   P+ PP + G      +  +   +   G+  ++  P    +PG  G + H      +
Sbjct: 252 GSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPK 311

Query: 244 GEKPDRGAPQEGGAQRTAGA-------GLPG-----GPQEEGD--GVPCTPASAPTSGPA 289
           GE    G+  E G     GA       G+PG     GPQ      G    P      GP 
Sbjct: 312 GEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPL 371

Query: 290 PGLGPASWCLEPGSVAQGSPDPQQTP-SRMGREGE-GTHSSLGCSSLGMVVIADLSTDPT 347
              G + +   PG   +  P   + P    G+ GE G    +G   L   +  D  T   
Sbjct: 372 GIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTD-GTPGA 430

Query: 348 ELEERALEVAGPDGQASAISPASPRRKAADGGHR-RALPGCTSLTGETTGESGEAGQDGK 406
           +    +   +GP G  SA  P SP  + + G    R  PG   +     G  GEAG  G+
Sbjct: 431 KGPTGSPGTSGPPG--SAGPPGSPGPQGSTGPQGIRGQPGDPGV----PGFKGEAGPKGE 484

Query: 407 PPGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGPCVNQKQEPG 453
           P    + GP       PG        GD G   P  GP V ++  PG
Sbjct: 485 PGPHGIQGPIG----PPGEEGKRGPRGDPGTVGP-PGP-VGERGAPG 525



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 72/243 (29%), Positives = 83/243 (34%), Gaps = 45/243 (18%)

Query: 225 DRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPASAP 284
           D   G G Q   +P   S G    RG     G Q   GAG  G P E GD  P  P  + 
Sbjct: 199 DEKSGLGSQVGLMPG--SVGPVGPRGPQGLQGQQ--GGAGPTGPPGEPGDPGPMGPIGSR 254

Query: 285 TSGPAPGL----GPASWCLEPGSVA-QGSPDPQQTPSRMGREG-EGTHSSLGCSSLGMVV 338
                PG     G       PG V   GSP  +  P   G  G +G     G       V
Sbjct: 255 GPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEV 314

Query: 339 IADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGE--TTG 396
            A  S             AGP G   A+ P  P          R +PG     G     G
Sbjct: 315 GAPGSKGE----------AGPTGPMGAMGPLGP----------RGMPGERGRLGPQGAPG 354

Query: 397 ESGEAGQDGKPPGDVLVGPTASLALAPGSG----ESMMG-AGDSGHASPDTGPCVNQKQE 451
           + G  G  GKP      GP   L +   SG      M G AG +G   P+ GP   Q+ E
Sbjct: 355 QRGAHGMPGKP------GPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPE-GP-QGQRGE 406

Query: 452 PGP 454
            GP
Sbjct: 407 TGP 409


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 96/350 (27%), Positives = 116/350 (33%), Gaps = 50/350 (14%)

Query: 162 GDPTQADSARPEQSSQSPVQAVPG-SGDSQPDDPPDRGTGLSASQRASQDHLSEQGADDS 220
           G P       P      P    PG  G   P  PP    G S   +A    L  +     
Sbjct: 83  GKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPP----GFSRMGKAGPPGLPGKVGPPG 138

Query: 221 KPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTP 280
           +P     PG              G++  RG P   G    +G  +PG P  +  GVP  P
Sbjct: 139 QPGLRGEPG------------IRGDQGLRGPPGPPGLPGPSGITIPGKPGAQ--GVPGPP 184

Query: 281 ASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIA 340
                 GP    GP       G    G P     P + G    G     G + LG   + 
Sbjct: 185 GFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGG--APGPPGLPGPAGLGKPGLD 242

Query: 341 DLSTDPTELEERALE-VAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGE--TTGE 397
            L   P +  E     V GP G+  A+ P  P     DG     +PG   L G    +G 
Sbjct: 243 GLPGAPGDKGESGPPGVPGPRGEPGAVGPKGP--PGVDG---VGVPGAAGLPGPQGPSGA 297

Query: 398 SGEAGQDGKPPGDVLVGPTASLALAPGSGESMMG-AGDSGHASPDTGP-CVNQKQEPGPA 455
            GE G  G PPG  L+GPT         G  M G  G  G   P   P  +  + EPG  
Sbjct: 298 KGEPGTRG-PPG--LIGPT---------GYGMPGLPGPKGDRGPAGVPGLLGDRGEPGED 345

Query: 456 QEEAELGGQNLERDLEGFRVSPQASVVLEHREIADDPLQE--PGAQQGIP 503
            E  E G Q L     G       S  L  R     P  E  PG   G+P
Sbjct: 346 GEPGEQGPQGL-----GGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVP 390



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 72/271 (26%), Positives = 89/271 (32%), Gaps = 52/271 (19%)

Query: 181 QAVPGSGDSQPDDPPDRGTGLSASQRASQDHLSEQGADDSKPETDRVPGDGGQKEHLPSI 240
           Q  PG    +P  P DRG  L       Q  L         P    +PG  G  +  P +
Sbjct: 187 QGEPGP-QGEPGPPGDRG--LKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGK--PGL 241

Query: 241 D----SEGEKPDRGAPQEGGAQRTAGA-GLPGGPQEEGDGVPCTPASAPTSGPA------ 289
           D    + G+K + G P   G +   GA G  G P  +G GVP         GP+      
Sbjct: 242 DGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEP 301

Query: 290 -----PGL-GPASWCLEPGSVAQGSPDPQQTPSRMGREGE----GTHSSLGCSSLGMVVI 339
                PGL GP  + +      +G   P   P  +G  GE    G     G   LG    
Sbjct: 302 GTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLG---- 357

Query: 340 ADLSTDPTELEERA-----LEVAGPDGQASAISPASPRRKAADGGH-----------RRA 383
                 P  L   A         GP G+A    P        D G             R 
Sbjct: 358 -----GPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERG 412

Query: 384 LPGCTSLTGETTGESGEAGQDGKPPGDVLVG 414
           LPG     G T G  GE G  G+P G  + G
Sbjct: 413 LPGAHGPPGPT-GPKGEPGFTGRPGGPGVAG 442


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 56.2 bits (134), Expect = 9e-08
 Identities = 102/452 (22%), Positives = 159/452 (35%), Gaps = 70/452 (15%)

Query: 44   EEPEGKLGPVPSTQQHGEEPGKAVSSSPDEETGSPCRLLRQPEKEPAPLPPSQNSFGRFV 103
            +E EG+  P     +  E  G+A   S D ET        QPE E A  P ++       
Sbjct: 1861 QEAEGEAQPESEDVEAPEAEGEAQPESEDVETPE-AEWEVQPESEGAEAPEAEKEAQ--- 1916

Query: 104  PQFAKSRKTVTRKEEMKDEDRGSGAFSLETIAESSAQSPGCQLLVETLGVPLQEATELGD 163
                ++      + E +DE    GA + E  AE +AQ    Q   E+  +  QEA E   
Sbjct: 1917 ---PETESVEALETEGEDEPESEGAEAQE--AEEAAQEAEGQTQPESEVIESQEAEEEAQ 1971

Query: 164  PTQADSARPE------------QSSQSPVQAVPGSGDSQ--PDDPPDRGTGLSASQRASQ 209
            P   D    E            Q     V+A    G+ Q   ++      G+ A  ++  
Sbjct: 1972 PESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEG 2031

Query: 210  DHLSEQGADDSKPETDRVPGDGG-----QKEHLPSIDSEGEKPDRGAPQEG---GAQRTA 261
            +   E   +  K E D  P   G      +E     + E ++ +  A  E     AQ   
Sbjct: 2032 EEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAE 2091

Query: 262  GAGLP-----GGPQEEGDGVPCTPASAP-TSGPAPGLGPASWCLE-PGSVAQGSPDPQQT 314
            G   P       P+ EG+        AP T G A    P S  +E P +  +  P+ +  
Sbjct: 2092 GEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQ---PESEGIEAPEAEGEAQPESEGV 2148

Query: 315  PSRMGREGEGTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRK 374
             ++   EGE    S G       + A  + +  + E   +E    +G+A   S       
Sbjct: 2149 EAQ-DAEGEAQPESEG-------IEAQEAEEEAQPELEGVEAPEAEGEAQPESEGI-EAP 2199

Query: 375  AADGGHRRALPGCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLALAP----------- 423
             A+G  +  L G          E+ EA ++ +P  + +  P A     P           
Sbjct: 2200 EAEGEAQPELEGV---------EAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKK 2250

Query: 424  GSGESMMGAGDSGHASPDTGPCVNQKQEPGPA 455
            GS +  +G G S  AS  + P    +  P P+
Sbjct: 2251 GSPQVSLGDGQSEEASESSSPVPEDRPTPPPS 2282



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 121/521 (23%), Positives = 178/521 (34%), Gaps = 113/521 (21%)

Query: 65   KAVSSSPDEETGSPCRLLRQPEKEPAPLPPSQNSFGRFVPQFAKSRKTVTRKEEMKDEDR 124
            +  SS+P   T S     R   +  A   PS    GR  P+    R +  RK+     D 
Sbjct: 622  EGASSTPSTCTSSQQGQRRHRSRASAMSSPSSPGLGRVAPR-GHPRHSHYRKDTHSPLD- 679

Query: 125  GSGAFSLETIAESSAQSPGCQLLVETLGVPLQEATELGDPTQAD-SARPEQSSQSPVQAV 183
                    ++ +   + P  +   +   VP    +     TQA  + RP  S   P Q +
Sbjct: 680  -------SSVTKQVPRPPERRRACQDGSVPRYSGSSSSTRTQASGNLRPPSSGSLPSQDL 732

Query: 184  PGSGDSQ--PDDPPDRGTGLSASQRASQDHLSEQGADDSKPETDRVP---GDGGQKEHLP 238
             G+  +   P    D  +G+S     S     + G+    P    +P    D   K    
Sbjct: 733  LGTSSATVTPAVHSDFVSGVSPHNAPSAGWAGDAGSRTCSPAP--IPPHTSDSCSKSGAA 790

Query: 239  SIDSEGEKPDR---------GAPQEG--GAQRTAGAGLPG---------GPQEEGD---- 274
            S+  E     +         G P++G  G  R+     PG         GP  E      
Sbjct: 791  SLGEEARDTPQPSSPLVLQVGRPEQGAVGPHRSHCCSQPGTQPAQEAQRGPSPEASWLCG 850

Query: 275  --------GVPC----------TPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPS 316
                    G PC          T +S  ++   PG  P     +PG     SP P    S
Sbjct: 851  RYCPTPPRGRPCPQRRSSSCGSTGSSHQSTARGPGGSPQEGTRQPGPTP--SPGPNSGAS 908

Query: 317  RMGREGEGTHSSLGCSSLGMVVIADLSTDPTELEERALEV-AGPDGQ--ASAISPASPRR 373
            R       + +S G  S G+             EE+ L    GP GQ  AS +SP+S  R
Sbjct: 909  RR------SSASQGAGSRGL------------SEEKTLRSGGGPQGQEEASGVSPSSLPR 950

Query: 374  KAADGGHRRALPGCT--------SLTGETTGESG--------EAGQDG--KPPGDVLVGP 415
             + +   R  L             L  ETTG +G        + G D   +  G+     
Sbjct: 951  SSPEAVVREWLDNIPEEPILMTYELADETTGAAGGGLRGPEVDPGDDHSLEGLGEPAQAG 1010

Query: 416  TASLALAPGSGE----SMMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELGGQNLERDLE 471
              SL   PG       +++G+ D+G   P +G  V Q   P    E     G + E    
Sbjct: 1011 QQSLEGDPGQDPEPEGALLGSSDTG---PQSGEGVPQGAAPEGVSEAPAEAGADREAP-A 1066

Query: 472  GFRVSPQASVVLEHREIADDPLQEP--GAQQGIPDTTSELA 510
            G RVS +A   L  R  A   +     G++QG P +  E++
Sbjct: 1067 GCRVSLRA---LPGRVSASTQIMRALMGSKQGRPSSVPEVS 1104



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 68/249 (27%), Positives = 94/249 (37%), Gaps = 40/249 (16%)

Query: 32   PQSSMLGCLHHPEEPEGKLGPVPSTQQHGEEPGKAVSSSPDEETGSPCRLLRQPEKEPAP 91
            P++S L   + P  P G+  P   +   G   G +  S+     GSP    RQP   P+P
Sbjct: 843  PEASWLCGRYCPTPPRGRPCPQRRSSSCGST-GSSHQSTARGPGGSPQEGTRQPGPTPSP 901

Query: 92   LPPSQNSFGRFVPQFAKSR-----KTVTRKEEMKDEDRGSGAFSLETIAESSAQSPGCQL 146
             P S  S      Q A SR     KT+      + ++  SG  S  ++  SS ++   + 
Sbjct: 902  GPNSGASRRSSASQGAGSRGLSEEKTLRSGGGPQGQEEASGV-SPSSLPRSSPEAVVREW 960

Query: 147  LVETLGVPLQEATELGDPTQADSARPEQSSQSPVQAVPGSGDSQPD-DPPDRGT--GLSA 203
            L      P+    EL D T                   G G   P+ DP D  +  GL  
Sbjct: 961  LDNIPEEPILMTYELADET---------------TGAAGGGLRGPEVDPGDDHSLEGLGE 1005

Query: 204  SQRASQDHLSEQGADDSKPE------TDRVPGDGGQKEHLPSIDSEGEKPD--RGAPQEG 255
              +A Q  L      D +PE      +D  P  G   E +P    +G  P+    AP E 
Sbjct: 1006 PAQAGQQSLEGDPGQDPEPEGALLGSSDTGPQSG---EGVP----QGAAPEGVSEAPAEA 1058

Query: 256  GAQRTAGAG 264
            GA R A AG
Sbjct: 1059 GADREAPAG 1067



 Score = 31.2 bits (69), Expect = 3.0
 Identities = 53/249 (21%), Positives = 79/249 (31%), Gaps = 29/249 (11%)

Query: 44   EEPEGKLGPVPSTQQHGEEPGKAVSSSPDEETGSPCRLLRQPEKEPAPLPPSQNSFGRFV 103
            E PE +     +  +  E  G+A   S D +         QPE E    P ++       
Sbjct: 2056 EAPEAEEEAQEAEGEVQEAEGEAHPESEDVDA-QEAEGEAQPESEGVEAPEAEGE----- 2109

Query: 104  PQFAKSRKTVTRKEEMKDEDRGSGAFSLETIAESS-----AQSPGCQLLVETLGVPLQEA 158
             Q A+  +    + E + E  G  A   E  A+       AQ    +   E+ G+  QEA
Sbjct: 2110 AQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEA 2169

Query: 159  TELGDPTQADSARPE-----QSSQSPVQAVPGSGDSQPD-------------DPPDRGTG 200
             E   P       PE     Q     ++A    G++QP+              P   G  
Sbjct: 2170 EEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVE 2229

Query: 201  LSASQRASQDHLSEQGADDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRT 260
               ++  +Q     +   + K       GDG  +E   S     E      P  GG    
Sbjct: 2230 TPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTPH 2289

Query: 261  AGAGLPGGP 269
               G   GP
Sbjct: 2290 QRPGSQTGP 2298


>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
          Length = 1192

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 67/287 (23%), Positives = 93/287 (32%), Gaps = 26/287 (9%)

Query: 178 SPVQAVPGSGDSQPDDPPDRGTGLSASQRASQDHLSEQGADDSKPETDRVPGDGGQKEHL 237
           SP  A  G+  ++  +  D G+   A +   + H       D+   +    G GG +   
Sbjct: 33  SPSAAAAGAAGARGSETGDPGSPRGAEEPGKKRHERLFHRQDALWISTSSAGTGGAEP-- 90

Query: 238 PSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPASAPTSGPAPGLGPASW 297
           P++      P R      G + +  A  PG P   G      P  APTS   P L   SW
Sbjct: 91  PALSPAPASPARPVSPAPGRRLSLWAVPPGPPLSGGLSPDPKPGGAPTSSRRPLLSSPSW 150

Query: 298 CLEPGSVAQGSPDPQQTPSRMGREGEG------THSSLGCSSLGMVVIADLSTDPTELEE 351
                    G P+P+      GR G G       H   G   L +            +  
Sbjct: 151 ---------GGPEPE------GRAGGGIPGSSSPHPGTGSRRLKVAPPPPAPKPCKTVTT 195

Query: 352 RALEVAGPDGQASAIS-PASPRRKAADGGHRRALPGCTSLTGETTGESGEAGQDGKPPGD 410
              +  G  G  S +S P S  +    G    A  G +     T   +G  G      G 
Sbjct: 196 SGAKAGGGKGAGSRLSWPESEGKPRVKGSKSSAGTGASVSAAATAAAAGGGGSTASTSGG 255

Query: 411 VLVGPTASLALAPGSGESMMGAGDSGHASPDTG--PCVNQKQEPGPA 455
           V  G  A   L+P  G+S        H  P  G  P +     P PA
Sbjct: 256 VGAGAGARGKLSPRKGKSKTLDNSDLHPGPPAGSPPPLTLPPTPSPA 302


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 79/320 (24%), Positives = 105/320 (32%), Gaps = 53/320 (16%)

Query: 166 QADSARPEQSSQSPVQAVPGS-GDSQPDDPPD-------RGTGLSASQRASQDHLSEQGA 217
           + +   P    +  +Q  PG  G   P  PP         G   +A    +  H+   G 
Sbjct: 352 KGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGP 411

Query: 218 DDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGA-------GLPGGPQ 270
                     PG  G      +   +GE+ ++GA  E G+    G        GLPG P 
Sbjct: 412 SGP-------PGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG 464

Query: 271 EEGDGVPCTPASAPTSGP--------APGL-GPASWCLEPGSVAQGSPDPQQTPSRMGRE 321
           +  DG P    S    GP        APG+ G      +PG    G P P   P   G  
Sbjct: 465 KGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSP 524

Query: 322 GE-------GTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRK 374
           G        G     G   L  ++       P ++   A +V           P  P  K
Sbjct: 525 GSRGLPGFPGPQGPAGRDGLSSLL------SPGDINLLAKDVCNDCPPGPPGLPGLPGFK 578

Query: 375 AADGGHRRALPGCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGAGD 434
              G     +PG     G T G+ GEAG  G P    + GP  S       GE +   GD
Sbjct: 579 GDKG-----VPGKPGREG-TEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGE-VGQKGD 631

Query: 435 SGHASPDTGPCVNQKQEPGP 454
            GH  P     +     PGP
Sbjct: 632 QGH--PGVPGFMGPPGNPGP 649



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 68/233 (29%), Positives = 79/233 (33%), Gaps = 52/233 (22%)

Query: 226 RVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGP--------QEEGDGVP 277
           R+PG+ G K         GEK D G P E G Q   G   P GP        QE   G P
Sbjct: 344 RMPGEQGPK---------GEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAP 394

Query: 278 CTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMV 337
               +    G     GP+     PGSV  G+P  + TP + G  GE   +          
Sbjct: 395 GAAGNPGAPGHVGAPGPSG---PPGSV--GAPGLRGTPGKDGERGEKGAAG--------- 440

Query: 338 VIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADG-GHRRALPGCTSLTGETTG 396
                       EE +    GP G   A     P  K  DG    R  PG     G T G
Sbjct: 441 ------------EEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLG-TKG 487

Query: 397 ESGEAGQDGKP-----PGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGP 444
           + G  G  G P     PG  + GP       PG   S    G  G   P  GP
Sbjct: 488 DRGAPGIPGSPGSRGDPGIGVAGPPGPSG-PPGDKGSPGSRGLPGFPGPQ-GP 538



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 80/308 (25%), Positives = 104/308 (33%), Gaps = 53/308 (17%)

Query: 193 DPPDRGTGLSASQRASQDHLSEQG--------ADDSKPETDRVPGDGGQKEHLPSIDSEG 244
           +P +RG      +   +  + EQG         +   P     PG  G+K        +G
Sbjct: 251 EPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEK------GDQG 304

Query: 245 EKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPASAPTSGPAPG-LGPASWCLEPGS 303
           EK + G P   G +   G   P GP     G+P T +        PG  GP     +PG 
Sbjct: 305 EKGELGLPGLKGDRGEKGEAGPAGP----PGLPGTTSLFTPHPRMPGEQGPKGEKGDPG- 359

Query: 304 VAQGSPDPQQTPSRMGREG----------EGTHSSLGCS----SLGMVVIADLSTDPTEL 349
              G P  Q  P  +G +G          EG H + G +    + G V     S  P  +
Sbjct: 360 -LPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSV 418

Query: 350 EERALE-VAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGET-TGESGEAGQDGKP 407
               L    G DG+      A         G  R  PG   L G    G+ GE G  G P
Sbjct: 419 GAPGLRGTPGKDGERGEKGAAGEEGSPGPVG-PRGDPGAPGLPGPPGKGKDGEPGLRGSP 477

Query: 408 PGDVLVGP--TASLALAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELGGQN 465
               L GP  T     APG   S    GD G         +     PGP+    + G   
Sbjct: 478 G---LPGPLGTKGDRGAPGIPGSPGSRGDPG---------IGVAGPPGPSGPPGDKGSPG 525

Query: 466 LERDLEGF 473
             R L GF
Sbjct: 526 -SRGLPGF 532



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 62/220 (28%), Positives = 79/220 (35%), Gaps = 36/220 (16%)

Query: 214 EQGAD--DSKPETDRVPGDGGQKEHLPSIDS-------EGEKPDRGAPQEGGAQRTAGA- 263
           E+G +  D KP     PG  G+   LP  +        +G   D GAP   G     G  
Sbjct: 688 EEGKEGRDGKPGPPGEPGKAGEPG-LPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLP 746

Query: 264 GLPGGPQEEGDGVPCTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGE 323
           G  G P ++GD  P  P      GP    GP      PGS   G P P  TP + G +GE
Sbjct: 747 GQEGLPGKDGDTGPTGP-----QGPQGPRGPPGKNGSPGS--PGEPGPSGTPGQKGSKGE 799

Query: 324 GTHSSLGCSSLGMVVIADLSTDPTELEERALE----VAGPDGQ----ASAISPASPRRKA 375
                    S G+         P E  E+ +     V G  G+         P     K 
Sbjct: 800 N-------GSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKG 852

Query: 376 ADGGHRRALPGCTSLTGETTGESGEAGQDGKPPGDVLVGP 415
             GG  +  PG   + G   G +G  G  G P  +  VGP
Sbjct: 853 PPGG--KGQPGDPGIPGH-KGHTGLMGPQGLPGENGPVGP 889



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 100/391 (25%), Positives = 129/391 (32%), Gaps = 117/391 (29%)

Query: 162 GDPTQADSARPEQSSQSPVQAVPGS----GDSQPDDPPDRGTGLSASQRASQDHLSEQGA 217
           GDP    +  P  S     +  PGS    G   P  P  R    S       + L++   
Sbjct: 502 GDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVC 561

Query: 218 DDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGA-------GLPG--- 267
           +D  P    +PG       LP     G K D+G P + G + T G        GLPG   
Sbjct: 562 NDCPPGPPGLPG-------LP-----GFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPG 609

Query: 268 --GPQ-------------EEGD----GVPCTPASAPTSGPAPGLGPASWCLEPGSVAQGS 308
             GPQ             ++GD    GVP         GP    G A     PG   QGS
Sbjct: 610 IAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPG--IQGS 667

Query: 309 PDPQQTPSRMGREGEGTHSSLGCSSLGMVVIADLSTDPTELEERALE-VAGPDGQ-ASAI 366
           P  +  P   G  G                   L   P E  +   +   GP G+   A 
Sbjct: 668 PGKEGPPGPQGPSG-------------------LPGIPGEEGKEGRDGKPGPPGEPGKAG 708

Query: 367 SPASPRRKAADGGHRRALPGCTSLTGET--------TGESGEAGQDGKPPGDVLVGPTAS 418
            P  P  + A G      PG    TG++        +G  G  GQ+G P  D   GPT  
Sbjct: 709 EPGLPGPEGARGP-----PGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPT-- 761

Query: 419 LALAPGSGESMMGAGDSGHASPDTGPCVN----QKQEPGPAQEEAELG--GQNLERDLEG 472
                         G  G   P   P  N       EPGP+    + G  G+N    L G
Sbjct: 762 --------------GPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPG 807

Query: 473 FRVSPQASVVLEHREIADDPLQEPGAQQGIP 503
           F + P+             P  EPG ++G+P
Sbjct: 808 F-LGPRG------------PPGEPG-EKGVP 824



 Score = 32.7 bits (73), Expect = 1.0
 Identities = 37/127 (29%), Positives = 46/127 (36%), Gaps = 7/127 (5%)

Query: 181  QAVPGS-GDSQPDDPPDRGTGLSASQRASQDHLSEQGADDSKPETDR-VPGDGGQKEHLP 238
            Q  PG  G    D  P R   +    R  Q  L E  +    P+ +R   GD G     P
Sbjct: 943  QGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGL-EGPSGPIGPKGERGAKGDPGA----P 997

Query: 239  SIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPASAPTSGPAPGLGPASWC 298
             +   GE    G P + G    A  GLPG P  +G+  P      P     PG    S C
Sbjct: 998  GVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQC 1057

Query: 299  LEPGSVA 305
                S+A
Sbjct: 1058 AYFASLA 1064



 Score = 31.6 bits (70), Expect = 2.3
 Identities = 26/77 (33%), Positives = 33/77 (42%), Gaps = 6/77 (7%)

Query: 393 ETTGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGPCVNQKQEP 452
           +  GE GE G+DG P    L G      LA   GE     G++G       P V  + E 
Sbjct: 247 QLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEK----GEAGLPGAPGFPGV--RGEK 300

Query: 453 GPAQEEAELGGQNLERD 469
           G   E+ ELG   L+ D
Sbjct: 301 GDQGEKGELGLPGLKGD 317


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 73/263 (27%), Positives = 95/263 (36%), Gaps = 61/263 (23%)

Query: 218  DDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDG-V 276
            +  KP  D +PG  GQK               G P + G       GLPG   ++GDG +
Sbjct: 1165 EKGKPGQDGIPGPAGQK---------------GEPGQPGFGNPGPPGLPGLSGQKGDGGL 1209

Query: 277  PCTPASAPTSGPA--------PGL-GPASWCLEPGSVAQG---SPDPQQTPSRMGREG-E 323
            P  P +    GP         PG+ GP      PG   +G   +P PQ  P R G  G E
Sbjct: 1210 PGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPE 1269

Query: 324  GTHSSLGCSSL----------GMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRR 373
            G     G   +          G+  +  L  D            GP G     +P  P  
Sbjct: 1270 GPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQ-----------GPPGLQG--NPGRPGL 1316

Query: 374  KAADGGHRRALPGCTSLTGET--TGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMG 431
                G     LPG     G    +G  G AG +G+P    L+GP     L   SG+S++ 
Sbjct: 1317 NGMKGDP--GLPGVPGFPGMKGPSGVPGSAGPEGEPG---LIGPPGPPGLPGPSGQSIII 1371

Query: 432  AGDSGHASPDTGPCVNQKQEPGP 454
             GD+G       P    K  PGP
Sbjct: 1372 KGDAGPPGIPGQP--GLKGLPGP 1392



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 86/319 (26%), Positives = 110/319 (34%), Gaps = 72/319 (22%)

Query: 162 GDPTQ-ADSARP-EQSSQSPVQAVPGSGDSQPDDPPD-RGT----GLSASQRASQDHLSE 214
           G P Q ++  RP +   Q   Q +PG  D  P  PP  RG     G    ++  Q    +
Sbjct: 239 GPPGQISEQKRPIDVEFQKGDQGLPG--DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGK 296

Query: 215 QG-----ADDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQ----------- 258
           +G      ++ +P    +PGD G          +G+K D G P   G             
Sbjct: 297 RGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIG 356

Query: 259 RTAGAGLPGGPQEEGD-GVPCTPASAPTSGPAPGL-GPASWCLEPGSVAQGSPDPQQTPS 316
                GLPG P E+G+ G P         GP PGL GP      PG+   G P P   P 
Sbjct: 357 EKGNIGLPGLPGEKGERGFP------GIQGP-PGLPGP------PGAAVMGPPGPPGFPG 403

Query: 317 RMGREGEGTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAA 376
             G++G+      G   + +     L   P      A  + GP G A    P S      
Sbjct: 404 ERGQKGDE-----GPPGISIPGPPGLDGQP-----GAPGLPGPPGPAGPHIPPSDEICEP 453

Query: 377 DGGHRRALPGCTSLTGET---------------TGESGEAGQDGKPPGDVLVGPTASLAL 421
                   PG   L GE                TG SG  GQ G P    L GP  SL  
Sbjct: 454 GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPG---LPGPPGSLGF 510

Query: 422 APGSGESMMGAGDSGHASP 440
               GE     G +G   P
Sbjct: 511 PGQKGEK----GQAGATGP 525



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 73/271 (26%), Positives = 94/271 (34%), Gaps = 51/271 (18%)

Query: 244  GEKPDRGAPQEGGAQRTAGAGLPGGPQEEG-DGVPCTPASAPTSGPAPGLGPASWCLEPG 302
            G K DRG P           G PG P   G DG+P        +G    +GP      PG
Sbjct: 772  GPKGDRGFP-----------GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL---PG 817

Query: 303  SVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQ 362
               QG P P   P  +G+ G                +  +  +  +     L+V GP G+
Sbjct: 818  IGVQGPPGPPGIPGPIGQPG----------------LHGIPGEKGDPGPPGLDVPGPPGE 861

Query: 363  -ASAISPASPRRKAADGGHRRALPGCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLAL 421
              S   P +P      G     LPG    +G   G  GE G  G P      GP   L +
Sbjct: 862  RGSPGIPGAPGPIGPPGS--PGLPGKAGASG-FPGTKGEMGMMGPP------GPPGPLGI 912

Query: 422  APGSGESMMGAGDSGHASPD-TGPC--VNQKQEPG----PAQEEAELGGQNLERDLEGFR 474
               SG   +   D     P   GP      K EPG    P   +  L G   E+   G  
Sbjct: 913  PGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLP 972

Query: 475  VSPQASVVLEHREIADDPLQEPG--AQQGIP 503
              P  S    ++ +  DP Q PG   Q G+P
Sbjct: 973  GIPGVSGPKGYQGLPGDPGQ-PGLSGQPGLP 1002



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 61/232 (26%), Positives = 79/232 (34%), Gaps = 45/232 (19%)

Query: 227  VPGDGGQKEH--------LPSIDSEGEKPDRGAPQ-EGGAQRTAGAGLPGGPQEEGDGVP 277
            +PG+GG K          LP +   G K D+G P  +G   R    G+ G P     G+P
Sbjct: 1274 LPGNGGIKGEKGNPGQPGLPGLP--GLKGDQGPPGLQGNPGRPGLNGMKGDP-----GLP 1326

Query: 278  CTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMV 337
              P      GP+   G A    EPG +  G P P   P              G S   ++
Sbjct: 1327 GVPGFPGMKGPSGVPGSAGPEGEPGLI--GPPGPPGLP--------------GPSGQSII 1370

Query: 338  VIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGET--- 394
            +  D        +     + GP G      P  P     D G R  LPG     G     
Sbjct: 1371 IKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGP---PGDPG-RNGLPGFDGAGGRKGDP 1426

Query: 395  --TGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGP 444
               G+ G  G DG P  D L GP       PG+     G   + H+     P
Sbjct: 1427 GLPGQPGTRGLDGPPGPDGLQGPPG----PPGTSSVAHGFLITRHSQTTDAP 1474



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 71/265 (26%), Positives = 81/265 (30%), Gaps = 35/265 (13%)

Query: 218  DDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVP 277
            D   P     PG  GQ    P +      P    P+ G +      GLPG P   G G  
Sbjct: 1102 DPGLPGLPGTPGAKGQ----PGLPGFPGTPGPPGPK-GISGPPGNPGLPGEPGPVGGGGH 1156

Query: 278  CTPASAPTSGPAPGL----GPASWCLEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSS 333
                  P     PG     GPA    EPG    G+P P   P   G++G+G         
Sbjct: 1157 PGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDG--------- 1207

Query: 334  LGMVVIADLSTDPTELEERALE----VAGPDGQASAISPASPRRKAADGGH----RRALP 385
             G+  I      P    E        V GP G   +  PA    K   G      R  LP
Sbjct: 1208 -GLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLP 1266

Query: 386  GCTSL-----TGETTGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGA--GDSG-H 437
            G          G   GE G  GQ G P    L G      L    G   +    GD G  
Sbjct: 1267 GPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLP 1326

Query: 438  ASPDTGPCVNQKQEPGPAQEEAELG 462
              P           PG A  E E G
Sbjct: 1327 GVPGFPGMKGPSGVPGSAGPEGEPG 1351



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 89/334 (26%), Positives = 108/334 (32%), Gaps = 58/334 (17%)

Query: 172 PEQSSQSPVQAVPGSGDSQPDDPPDRGT-GLSASQRASQDHLSEQGADDSKPETDRVPGD 230
           P    +  +Q V G+   QP  P  +G  G + +Q          G D        +PGD
Sbjct: 628 PGPVGEKGIQGVAGN-PGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVG----LPGD 682

Query: 231 GGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEG-------DGVPCTPASA 283
            G    LP     G+    G P   G     G GLPG P  +G        G P TP   
Sbjct: 683 PG----LP-----GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRI 733

Query: 284 PTSGP--APGL-GPASWCLEPGSVAQGSPDPQQTPSRMGREG----------EGTHSSLG 330
              GP   PG  GP     EPG    G P P   P   G  G           G     G
Sbjct: 734 GLEGPPGPPGFPGPKG---EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTG 790

Query: 331 CSSL-GMVVIADLSTDPTELEERALE---VAGPDGQASAISP-ASPRRKAADGGHRRALP 385
              L G       +  P  +    L    V GP G      P   P      G   +  P
Sbjct: 791 LDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPG--EKGDP 848

Query: 386 GCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGA--GDSGHASPDTG 443
           G   L  +  G  GE G  G P     +GP  S  L   +G S      G+ G   P  G
Sbjct: 849 GPPGL--DVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP-PG 905

Query: 444 PCVNQKQEPGPAQEEAELGGQNLERDLEGFRVSP 477
           P       PGP       G   L+ D +G +  P
Sbjct: 906 P-------PGPLGIPGRSGVPGLKGD-DGLQGQP 931



 Score = 34.3 bits (77), Expect = 0.36
 Identities = 74/282 (26%), Positives = 90/282 (31%), Gaps = 74/282 (26%)

Query: 222 PETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGA----GLPGGPQEEGD--- 274
           P    +PG  G    L     +GEK   GA    G     GA    G PG   E GD   
Sbjct: 493 PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT 552

Query: 275 --------------GVPCTPASAPTSGP--APGL-GPASWCLEPGSVA-QGSPDPQQTPS 316
                         G P  P    T G    PGL GP     EPG +  +G   P   P 
Sbjct: 553 FPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKG---EPGGITFKGERGPPGNPG 609

Query: 317 RMGREGEGTHSSLGCSSLGMVVIADLSTDPTELEERALE-VAGPDGQASAISPASPRRKA 375
             G  G      +G    G          P  + E+ ++ VAG  GQ             
Sbjct: 610 LPGLPGN--IGPMGPPGFG---------PPGPVGEKGIQGVAGNPGQPG----------- 647

Query: 376 ADGGHRRALPGCTSLTGETTGESGEAGQDGKP--------PGDVLVGPTASLALAPGS-G 426
                   +PG     G+T  + G+ G  G P        PGD  +     L   PGS G
Sbjct: 648 --------IPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKG 699

Query: 427 E-SMMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELGGQNLE 467
           E  + G G  G   P   P +     PGP       G   LE
Sbjct: 700 EPGIPGIGLPGPPGPKGFPGI-----PGPPGAPGTPGRIGLE 736


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 116/447 (25%), Positives = 150/447 (33%), Gaps = 95/447 (21%)

Query: 43  PEEPEGKLGPVPSTQQHGEEPGKAVSSSP-----DEETGSPCRLLRQPEKEPAPLPPSQN 97
           P+ P G  GP       G+   K    +P     D E G+P      P     P PP   
Sbjct: 118 PKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTP----GNPGPPGPPGPPGPP 173

Query: 98  SFGRFVPQFAKSRKTVTRKEEMKDEDRGSGAFSLETIAESSAQSPGCQLLVETLGVPLQE 157
             G                          G F+ +       ++ G QL V  +  P+  
Sbjct: 174 GLG--------------------------GNFAAQMAGGFDEKAGGAQLGV--MQGPMGP 205

Query: 158 ATELGDPTQADSARPEQSSQSPVQ-AVPG-SGDSQPDDPP-------DRGTGLSASQRAS 208
               G P  A +  P+    +P +   PG SG   P  PP       D G      +   
Sbjct: 206 MGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGE 265

Query: 209 QDHLSEQGADDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGG 268
           +     QGA    P T  +PG  G + + P +D  G K + GAP   G          G 
Sbjct: 266 RGPPGPQGARGF-PGTPGLPGVKGHRGY-PGLD--GAKGEAGAPGVKGES--------GS 313

Query: 269 PQEEGDGVPCTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMG-REGEGTHS 327
           P E G   P  P   P  G     GPA      G+   G P P   P  +G   G G   
Sbjct: 314 PGENGSPGPMGPRGLP--GERGRTGPAGAAGARGN--DGQPGPAGPPGPVGPAGGPGFPG 369

Query: 328 SLGCSSLGMVVIADLSTDPTELEERALEVA-GPDGQASAISPASPRRKAADGGHRRALPG 386
           + G               PT    R  E A GP G+    +P SP    A G      PG
Sbjct: 370 APGAKG---------EAGPT--GARGPEGAQGPRGEPG--TPGSPGPAGASGN-----PG 411

Query: 387 CTSLTGE--TTGESGEAGQDG-----KPPGDVLVGPTASLALAPGSGESMMGAGDSGHAS 439
              + G   + G  G AG  G      PPG    G T  L     +GE  + AG  G   
Sbjct: 412 TDGIPGAKGSAGAPGIAGAPGFPGPRGPPGP--QGATGPLGPKGQTGEPGI-AGFKGEQG 468

Query: 440 P--DTGPCVNQKQEPGPAQEEAELGGQ 464
           P  + GP    +  PGPA EE + G +
Sbjct: 469 PKGEPGP-AGPQGAPGPAGEEGKRGAR 494



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 115/438 (26%), Positives = 149/438 (34%), Gaps = 73/438 (16%)

Query: 43  PEEPEGKLGPVPSTQQHGEEPGKAVSSSPDEETGSPCRLLRQPEKEPAPLPPSQNSFGRF 102
           P  P+G  GP+    Q GE PG A       E G        P+ EP P  P        
Sbjct: 439 PPGPQGATGPLGPKGQTGE-PGIAGFKG---EQG--------PKGEPGPAGP-------- 478

Query: 103 VPQFAKSRKTVTRKEEMKDEDRGSGAFSL--ETIAESSAQSPGCQLLVETLGVPLQEATE 160
             Q A        K   + E  G G      E  A  +   PG   L    G P      
Sbjct: 479 --QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAP------ 530

Query: 161 LGDPTQADSARPEQSSQSPVQAVPGSGDSQPDDPPDRGTGLSASQRASQDHLSEQGA--D 218
            G+   +  A P+ ++  P +  PG    +P  P  RG          Q  +   GA  +
Sbjct: 531 -GERGPSGLAGPKGANGDPGR--PG----EPGLPGARGLTGRPGDAGPQGKVGPSGAPGE 583

Query: 219 DSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGA-GLPGGPQEEGDGVP 277
           D +P     PG  G +     +   G K   G P + G +   GA GL G P ++G+   
Sbjct: 584 DGRPGP---PGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGE--- 637

Query: 278 CTPASAPTSGPAPGLGPASWCLEPG-SVAQGSPDPQQTPSRMGREGE-GTHSSLGCSSLG 335
            T A+ P  GPA   G       PG S  QG P P   P   G+ G+ G     G    G
Sbjct: 638 -TGAAGPP-GPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAP--G 693

Query: 336 MVVIADLSTDPTELEERALE----------VAGPDGQASAISPASPRRKAADGGHR---- 381
           +V        P E      +            G DG   A  PA P       G +    
Sbjct: 694 LVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPG 753

Query: 382 -RALPGCTSLTGET--TGESGEAGQDGKPPGDVLVGPTASLALAPGSGE--SMMGAGDSG 436
            R   G     G+    GE G  G  GK  G  L GP      A  +GE   +   G +G
Sbjct: 754 ERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAG 813

Query: 437 HASPDTGPCVNQKQEPGP 454
            A     P   ++ E GP
Sbjct: 814 SAGARGAP--GERGETGP 829



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 138/581 (23%), Positives = 175/581 (30%), Gaps = 132/581 (22%)

Query: 16  PPKPLKNPRLGDFYGDPQSSMLGCLHHPEEPEGKLGPVPSTQQHGE--EPGKAVSSSPDE 73
           PP P   P    F G+P       +  P  P G  GP       GE  +PGKA    P  
Sbjct: 211 PPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPG 270

Query: 74  ETGSPCRLLRQPEKEPAPLPPSQNSFGRFVPQFAKSRKTVTRKEEMKDEDRGSGAFSLET 133
             G+               P +    G       K  +     +  K E  G+     E+
Sbjct: 271 PQGA------------RGFPGTPGLPG------VKGHRGYPGLDGAKGE-AGAPGVKGES 311

Query: 134 IAESSAQSPGCQLLVETLGVPLQEATELGDPTQADSARPEQSSQSPV----QAVPGSGDS 189
            +     SPG    +   G+P +       P  A  AR       P        P  G  
Sbjct: 312 GSPGENGSPGP---MGPRGLPGERGRT--GPAGAAGARGNDGQPGPAGPPGPVGPAGGPG 366

Query: 190 QPDDPPDRGTGLSASQRASQDHLSEQGADDSKPETDRVPGDGGQKEHLPSIDSEGEKPDR 249
            P  P  +G       R  +     +G    +P T   PG  G   +  +    G K   
Sbjct: 367 FPGAPGAKGEAGPTGARGPEGAQGPRG----EPGTPGSPGPAGASGNPGTDGIPGAKGSA 422

Query: 250 GAPQEGGAQRTAGAGLPGGPQ-------------------------EEGDGVPCTPASAP 284
           GAP   GA    G   P GPQ                          +G+  P  P  AP
Sbjct: 423 GAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAP 482

Query: 285 TSGPAPGLGPASWCLEPGSVA-------QGSPDPQQTPSRMGREG-EGTHSSLGCSSLGM 336
             GPA   G      EPG V        +G+P  +  P + G  G +G     G S  G+
Sbjct: 483 --GPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPS--GL 538

Query: 337 VVIADLSTDPTELEERALE----VAGPDGQASAISPASPRRKAADGGH--------RRAL 384
                 + DP    E  L     + G  G A       P     + G          R  
Sbjct: 539 AGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ 598

Query: 385 PGCTSLTGE--TTGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGAGDSGHASP-- 440
           PG     G     GE G+AG+ G P    L G        PG       AG  G A P  
Sbjct: 599 PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRG-------LPGKDGETGAAGPPGPAGPAG 651

Query: 441 ------DTGPCVNQ--KQEPGPAQEEAELGGQNL--------------ERDLEGFRVSPQ 478
                   GP   Q     PGP  E  + G Q +              ER   G R SP 
Sbjct: 652 ERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPG 711

Query: 479 ASVVLEHREI-----------ADDPLQEPGAQ-----QGIP 503
           A  +   R +           A  P   PGAQ     QG+P
Sbjct: 712 AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMP 752



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 85/339 (25%), Positives = 109/339 (32%), Gaps = 78/339 (23%)

Query: 168  DSARPEQSSQSPVQAVPGSGDSQPDDPPDRGTGLSASQRASQDHLSEQGADD-----SKP 222
            D  R       P      +G+     PP  G   SA  R +     E G          P
Sbjct: 782  DGGRGLTGPIGPPGPAGANGEKGEVGPP--GPAGSAGARGAPGERGETGPPGPAGFAGPP 839

Query: 223  ETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQ-----EEGDGVP 277
              D  PG  G++         G+K D GAP   G Q  +GA  P GP      +   G  
Sbjct: 840  GADGQPGAKGEQ------GEAGQKGDAGAP---GPQGPSGAPGPQGPTGVTGPKGARGAQ 890

Query: 278  CTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREG-EGTHSSLGCSS-LG 335
              P +    G A  +GP      PGS   G+P P   P   G++G +G     G     G
Sbjct: 891  GPPGATGFPGAAGRVGP------PGS--NGNPGPPGPPGPSGKDGPKGARGDSGPPGRAG 942

Query: 336  MVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADGG--------HRRALPGC 387
               +   +  P E  E      G DG + A  P  P+  A   G          R  PG 
Sbjct: 943  EPGLQGPAGPPGEKGE-----PGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGL 997

Query: 388  TSLTGET-----------------------TGESGEAGQDGKPPGDVLVGPTASLALAPG 424
               +GE                        TG +GE G++G P  D   GP       PG
Sbjct: 998  PGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGAD---GP-------PG 1047

Query: 425  SGESMMGAGDSGHASPDTGP-CVNQKQEPGPAQEEAELG 462
               +    GD G       P        PGPA    + G
Sbjct: 1048 RDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1086



 Score = 31.2 bits (69), Expect = 3.0
 Identities = 36/109 (33%), Positives = 38/109 (34%), Gaps = 25/109 (22%)

Query: 215  QGADDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGD 274
            QG    K E    PG+ G K H            RG         T   GLPG P   GD
Sbjct: 1112 QGPRGDKGEAGE-PGERGLKGH------------RGF--------TGLQGLPGPPGPSGD 1150

Query: 275  GVPCTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGE 323
                 PA    SGP    GP     + G  A G P P   P   GR GE
Sbjct: 1151 QGASGPAG--PSGPRGPPGPVGPSGKDG--ANGIPGPIGPPGPRGRSGE 1195


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 116/447 (25%), Positives = 150/447 (33%), Gaps = 95/447 (21%)

Query: 43  PEEPEGKLGPVPSTQQHGEEPGKAVSSSP-----DEETGSPCRLLRQPEKEPAPLPPSQN 97
           P+ P G  GP       G+   K    +P     D E G+P      P     P PP   
Sbjct: 49  PKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTP----GNPGPPGPPGPPGPP 104

Query: 98  SFGRFVPQFAKSRKTVTRKEEMKDEDRGSGAFSLETIAESSAQSPGCQLLVETLGVPLQE 157
             G                          G F+ +       ++ G QL V  +  P+  
Sbjct: 105 GLG--------------------------GNFAAQMAGGFDEKAGGAQLGV--MQGPMGP 136

Query: 158 ATELGDPTQADSARPEQSSQSPVQ-AVPG-SGDSQPDDPP-------DRGTGLSASQRAS 208
               G P  A +  P+    +P +   PG SG   P  PP       D G      +   
Sbjct: 137 MGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGE 196

Query: 209 QDHLSEQGADDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGG 268
           +     QGA    P T  +PG  G + + P +D  G K + GAP   G          G 
Sbjct: 197 RGPPGPQGARGF-PGTPGLPGVKGHRGY-PGLD--GAKGEAGAPGVKGES--------GS 244

Query: 269 PQEEGDGVPCTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMG-REGEGTHS 327
           P E G   P  P   P  G     GPA      G+   G P P   P  +G   G G   
Sbjct: 245 PGENGSPGPMGPRGLP--GERGRTGPAGAAGARGN--DGQPGPAGPPGPVGPAGGPGFPG 300

Query: 328 SLGCSSLGMVVIADLSTDPTELEERALEVA-GPDGQASAISPASPRRKAADGGHRRALPG 386
           + G               PT    R  E A GP G+    +P SP    A G      PG
Sbjct: 301 APGAKG---------EAGPT--GARGPEGAQGPRGEPG--TPGSPGPAGASGN-----PG 342

Query: 387 CTSLTGE--TTGESGEAGQDG-----KPPGDVLVGPTASLALAPGSGESMMGAGDSGHAS 439
              + G   + G  G AG  G      PPG    G T  L     +GE  + AG  G   
Sbjct: 343 TDGIPGAKGSAGAPGIAGAPGFPGPRGPPGP--QGATGPLGPKGQTGEPGI-AGFKGEQG 399

Query: 440 P--DTGPCVNQKQEPGPAQEEAELGGQ 464
           P  + GP    +  PGPA EE + G +
Sbjct: 400 PKGEPGP-AGPQGAPGPAGEEGKRGAR 425



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 115/438 (26%), Positives = 149/438 (34%), Gaps = 73/438 (16%)

Query: 43  PEEPEGKLGPVPSTQQHGEEPGKAVSSSPDEETGSPCRLLRQPEKEPAPLPPSQNSFGRF 102
           P  P+G  GP+    Q GE PG A       E G        P+ EP P  P        
Sbjct: 370 PPGPQGATGPLGPKGQTGE-PGIAGFKG---EQG--------PKGEPGPAGP-------- 409

Query: 103 VPQFAKSRKTVTRKEEMKDEDRGSGAFSL--ETIAESSAQSPGCQLLVETLGVPLQEATE 160
             Q A        K   + E  G G      E  A  +   PG   L    G P      
Sbjct: 410 --QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAP------ 461

Query: 161 LGDPTQADSARPEQSSQSPVQAVPGSGDSQPDDPPDRGTGLSASQRASQDHLSEQGA--D 218
            G+   +  A P+ ++  P +  PG    +P  P  RG          Q  +   GA  +
Sbjct: 462 -GERGPSGLAGPKGANGDPGR--PG----EPGLPGARGLTGRPGDAGPQGKVGPSGAPGE 514

Query: 219 DSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGA-GLPGGPQEEGDGVP 277
           D +P     PG  G +     +   G K   G P + G +   GA GL G P ++G+   
Sbjct: 515 DGRPGP---PGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGE--- 568

Query: 278 CTPASAPTSGPAPGLGPASWCLEPG-SVAQGSPDPQQTPSRMGREGE-GTHSSLGCSSLG 335
            T A+ P  GPA   G       PG S  QG P P   P   G+ G+ G     G    G
Sbjct: 569 -TGAAGPP-GPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAP--G 624

Query: 336 MVVIADLSTDPTELEERALE----------VAGPDGQASAISPASPRRKAADGGHR---- 381
           +V        P E      +            G DG   A  PA P       G +    
Sbjct: 625 LVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPG 684

Query: 382 -RALPGCTSLTGET--TGESGEAGQDGKPPGDVLVGPTASLALAPGSGE--SMMGAGDSG 436
            R   G     G+    GE G  G  GK  G  L GP      A  +GE   +   G +G
Sbjct: 685 ERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAG 744

Query: 437 HASPDTGPCVNQKQEPGP 454
            A     P   ++ E GP
Sbjct: 745 SAGARGAP--GERGETGP 760



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 138/581 (23%), Positives = 175/581 (30%), Gaps = 132/581 (22%)

Query: 16  PPKPLKNPRLGDFYGDPQSSMLGCLHHPEEPEGKLGPVPSTQQHGE--EPGKAVSSSPDE 73
           PP P   P    F G+P       +  P  P G  GP       GE  +PGKA    P  
Sbjct: 142 PPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPG 201

Query: 74  ETGSPCRLLRQPEKEPAPLPPSQNSFGRFVPQFAKSRKTVTRKEEMKDEDRGSGAFSLET 133
             G+               P +    G       K  +     +  K E  G+     E+
Sbjct: 202 PQGA------------RGFPGTPGLPG------VKGHRGYPGLDGAKGE-AGAPGVKGES 242

Query: 134 IAESSAQSPGCQLLVETLGVPLQEATELGDPTQADSARPEQSSQSPV----QAVPGSGDS 189
            +     SPG    +   G+P +       P  A  AR       P        P  G  
Sbjct: 243 GSPGENGSPGP---MGPRGLPGERGRT--GPAGAAGARGNDGQPGPAGPPGPVGPAGGPG 297

Query: 190 QPDDPPDRGTGLSASQRASQDHLSEQGADDSKPETDRVPGDGGQKEHLPSIDSEGEKPDR 249
            P  P  +G       R  +     +G    +P T   PG  G   +  +    G K   
Sbjct: 298 FPGAPGAKGEAGPTGARGPEGAQGPRG----EPGTPGSPGPAGASGNPGTDGIPGAKGSA 353

Query: 250 GAPQEGGAQRTAGAGLPGGPQ-------------------------EEGDGVPCTPASAP 284
           GAP   GA    G   P GPQ                          +G+  P  P  AP
Sbjct: 354 GAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAP 413

Query: 285 TSGPAPGLGPASWCLEPGSVA-------QGSPDPQQTPSRMGREG-EGTHSSLGCSSLGM 336
             GPA   G      EPG V        +G+P  +  P + G  G +G     G S  G+
Sbjct: 414 --GPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPS--GL 469

Query: 337 VVIADLSTDPTELEERALE----VAGPDGQASAISPASPRRKAADGGH--------RRAL 384
                 + DP    E  L     + G  G A       P     + G          R  
Sbjct: 470 AGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ 529

Query: 385 PGCTSLTGE--TTGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGAGDSGHASP-- 440
           PG     G     GE G+AG+ G P    L G        PG       AG  G A P  
Sbjct: 530 PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRG-------LPGKDGETGAAGPPGPAGPAG 582

Query: 441 ------DTGPCVNQ--KQEPGPAQEEAELGGQNL--------------ERDLEGFRVSPQ 478
                   GP   Q     PGP  E  + G Q +              ER   G R SP 
Sbjct: 583 ERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPG 642

Query: 479 ASVVLEHREI-----------ADDPLQEPGAQ-----QGIP 503
           A  +   R +           A  P   PGAQ     QG+P
Sbjct: 643 AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMP 683



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 85/339 (25%), Positives = 109/339 (32%), Gaps = 78/339 (23%)

Query: 168  DSARPEQSSQSPVQAVPGSGDSQPDDPPDRGTGLSASQRASQDHLSEQGADD-----SKP 222
            D  R       P      +G+     PP  G   SA  R +     E G          P
Sbjct: 713  DGGRGLTGPIGPPGPAGANGEKGEVGPP--GPAGSAGARGAPGERGETGPPGPAGFAGPP 770

Query: 223  ETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQ-----EEGDGVP 277
              D  PG  G++         G+K D GAP   G Q  +GA  P GP      +   G  
Sbjct: 771  GADGQPGAKGEQ------GEAGQKGDAGAP---GPQGPSGAPGPQGPTGVTGPKGARGAQ 821

Query: 278  CTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREG-EGTHSSLGCSS-LG 335
              P +    G A  +GP      PGS   G+P P   P   G++G +G     G     G
Sbjct: 822  GPPGATGFPGAAGRVGP------PGS--NGNPGPPGPPGPSGKDGPKGARGDSGPPGRAG 873

Query: 336  MVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADGG--------HRRALPGC 387
               +   +  P E  E      G DG + A  P  P+  A   G          R  PG 
Sbjct: 874  EPGLQGPAGPPGEKGE-----PGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGL 928

Query: 388  TSLTGET-----------------------TGESGEAGQDGKPPGDVLVGPTASLALAPG 424
               +GE                        TG +GE G++G P  D   GP       PG
Sbjct: 929  PGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGAD---GP-------PG 978

Query: 425  SGESMMGAGDSGHASPDTGP-CVNQKQEPGPAQEEAELG 462
               +    GD G       P        PGPA    + G
Sbjct: 979  RDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1017



 Score = 31.2 bits (69), Expect = 3.0
 Identities = 36/109 (33%), Positives = 38/109 (34%), Gaps = 25/109 (22%)

Query: 215  QGADDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGD 274
            QG    K E    PG+ G K H            RG         T   GLPG P   GD
Sbjct: 1043 QGPRGDKGEAGE-PGERGLKGH------------RGF--------TGLQGLPGPPGPSGD 1081

Query: 275  GVPCTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGE 323
                 PA    SGP    GP     + G  A G P P   P   GR GE
Sbjct: 1082 QGASGPAG--PSGPRGPPGPVGPSGKDG--ANGIPGPIGPPGPRGRSGE 1126


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 73/266 (27%), Positives = 96/266 (36%), Gaps = 64/266 (24%)

Query: 218  DDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDG-V 276
            +  KP  D +PG  GQK               G P + G       GLPG   ++GDG +
Sbjct: 1165 EKGKPGQDGIPGPAGQK---------------GEPGQPGFGNPGPPGLPGLSGQKGDGGL 1209

Query: 277  PCTPASAPTSGPA--------PGL-GPASWCLEPGSVAQG---SPDPQQTPSRMGREG-- 322
            P  P +    GP         PG+ GP      PG   +G   +P PQ  P R G +G  
Sbjct: 1210 PGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLP 1269

Query: 323  --EGTHSSLGCSSL----------GMVVIADLSTDPTELEERALEVAGPDGQASAISPAS 370
              EG     G   +          G+  +  L  D            GP G     +P  
Sbjct: 1270 GPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQ-----------GPPGLQG--NPGR 1316

Query: 371  PRRKAADGGHRRALPGCTSLTGET--TGESGEAGQDGKPPGDVLVGPTASLALAPGSGES 428
            P      G     LPG     G    +G  G AG +G+P    L+GP     L   SG+S
Sbjct: 1317 PGLNGMKGDP--GLPGVPGFPGMKGPSGVPGSAGPEGEPG---LIGPPGPPGLPGPSGQS 1371

Query: 429  MMGAGDSGHASPDTGPCVNQKQEPGP 454
            ++  GD+G       P    K  PGP
Sbjct: 1372 IIIKGDAGPPGIPGQP--GLKGLPGP 1395



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 86/319 (26%), Positives = 110/319 (34%), Gaps = 72/319 (22%)

Query: 162 GDPTQ-ADSARP-EQSSQSPVQAVPGSGDSQPDDPPD-RGT----GLSASQRASQDHLSE 214
           G P Q ++  RP +   Q   Q +PG  D  P  PP  RG     G    ++  Q    +
Sbjct: 239 GPPGQISEQKRPIDVEFQKGDQGLPG--DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGK 296

Query: 215 QG-----ADDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQ----------- 258
           +G      ++ +P    +PGD G          +G+K D G P   G             
Sbjct: 297 RGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIG 356

Query: 259 RTAGAGLPGGPQEEGD-GVPCTPASAPTSGPAPGL-GPASWCLEPGSVAQGSPDPQQTPS 316
                GLPG P E+G+ G P         GP PGL GP      PG+   G P P   P 
Sbjct: 357 EKGNIGLPGLPGEKGERGFP------GIQGP-PGLPGP------PGAAVMGPPGPPGFPG 403

Query: 317 RMGREGEGTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAA 376
             G++G+      G   + +     L   P      A  + GP G A    P S      
Sbjct: 404 ERGQKGDE-----GPPGISIPGPPGLDGQP-----GAPGLPGPPGPAGPHIPPSDEICEP 453

Query: 377 DGGHRRALPGCTSLTGET---------------TGESGEAGQDGKPPGDVLVGPTASLAL 421
                   PG   L GE                TG SG  GQ G P    L GP  SL  
Sbjct: 454 GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPG---LPGPPGSLGF 510

Query: 422 APGSGESMMGAGDSGHASP 440
               GE     G +G   P
Sbjct: 511 PGQKGEK----GQAGATGP 525



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 73/271 (26%), Positives = 94/271 (34%), Gaps = 51/271 (18%)

Query: 244  GEKPDRGAPQEGGAQRTAGAGLPGGPQEEG-DGVPCTPASAPTSGPAPGLGPASWCLEPG 302
            G K DRG P           G PG P   G DG+P        +G    +GP      PG
Sbjct: 772  GPKGDRGFP-----------GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL---PG 817

Query: 303  SVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQ 362
               QG P P   P  +G+ G                +  +  +  +     L+V GP G+
Sbjct: 818  IGVQGPPGPPGIPGPIGQPG----------------LHGIPGEKGDPGPPGLDVPGPPGE 861

Query: 363  -ASAISPASPRRKAADGGHRRALPGCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLAL 421
              S   P +P      G     LPG    +G   G  GE G  G P      GP   L +
Sbjct: 862  RGSPGIPGAPGPIGPPGS--PGLPGKAGASG-FPGTKGEMGMMGPP------GPPGPLGI 912

Query: 422  APGSGESMMGAGDSGHASPD-TGPC--VNQKQEPG----PAQEEAELGGQNLERDLEGFR 474
               SG   +   D     P   GP      K EPG    P   +  L G   E+   G  
Sbjct: 913  PGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLP 972

Query: 475  VSPQASVVLEHREIADDPLQEPG--AQQGIP 503
              P  S    ++ +  DP Q PG   Q G+P
Sbjct: 973  GIPGVSGPKGYQGLPGDPGQ-PGLSGQPGLP 1002



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 61/232 (26%), Positives = 79/232 (34%), Gaps = 45/232 (19%)

Query: 227  VPGDGGQKEH--------LPSIDSEGEKPDRGAPQ-EGGAQRTAGAGLPGGPQEEGDGVP 277
            +PG+GG K          LP +   G K D+G P  +G   R    G+ G P     G+P
Sbjct: 1277 LPGNGGIKGEKGNPGQPGLPGLP--GLKGDQGPPGLQGNPGRPGLNGMKGDP-----GLP 1329

Query: 278  CTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMV 337
              P      GP+   G A    EPG +  G P P   P              G S   ++
Sbjct: 1330 GVPGFPGMKGPSGVPGSAGPEGEPGLI--GPPGPPGLP--------------GPSGQSII 1373

Query: 338  VIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGET--- 394
            +  D        +     + GP G      P  P     D G R  LPG     G     
Sbjct: 1374 IKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGP---PGDPG-RNGLPGFDGAGGRKGDP 1429

Query: 395  --TGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGP 444
               G+ G  G DG P  D L GP       PG+     G   + H+     P
Sbjct: 1430 GLPGQPGTRGLDGPPGPDGLQGPPG----PPGTSSVAHGFLITRHSQTTDAP 1477



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 89/334 (26%), Positives = 108/334 (32%), Gaps = 58/334 (17%)

Query: 172 PEQSSQSPVQAVPGSGDSQPDDPPDRGT-GLSASQRASQDHLSEQGADDSKPETDRVPGD 230
           P    +  +Q V G+   QP  P  +G  G + +Q          G D        +PGD
Sbjct: 628 PGPVGEKGIQGVAGN-PGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVG----LPGD 682

Query: 231 GGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEG-------DGVPCTPASA 283
            G    LP     G+    G P   G     G GLPG P  +G        G P TP   
Sbjct: 683 PG----LP-----GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRI 733

Query: 284 PTSGP--APGL-GPASWCLEPGSVAQGSPDPQQTPSRMGREG----------EGTHSSLG 330
              GP   PG  GP     EPG    G P P   P   G  G           G     G
Sbjct: 734 GLEGPPGPPGFPGPKG---EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTG 790

Query: 331 CSSL-GMVVIADLSTDPTELEERALE---VAGPDGQASAISP-ASPRRKAADGGHRRALP 385
              L G       +  P  +    L    V GP G      P   P      G   +  P
Sbjct: 791 LDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPG--EKGDP 848

Query: 386 GCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGA--GDSGHASPDTG 443
           G   L  +  G  GE G  G P     +GP  S  L   +G S      G+ G   P  G
Sbjct: 849 GPPGL--DVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP-PG 905

Query: 444 PCVNQKQEPGPAQEEAELGGQNLERDLEGFRVSP 477
           P       PGP       G   L+ D +G +  P
Sbjct: 906 P-------PGPLGIPGRSGVPGLKGD-DGLQGQP 931



 Score = 38.9 bits (89), Expect = 0.015
 Identities = 70/268 (26%), Positives = 81/268 (30%), Gaps = 38/268 (14%)

Query: 218  DDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVP 277
            D   P     PG  GQ    P +      P    P+ G +      GLPG P   G G  
Sbjct: 1102 DPGLPGLPGTPGAKGQ----PGLPGFPGTPGPPGPK-GISGPPGNPGLPGEPGPVGGGGH 1156

Query: 278  CTPASAPTSGPAPGL----GPASWCLEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSS 333
                  P     PG     GPA    EPG    G+P P   P   G++G+G         
Sbjct: 1157 PGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDG--------- 1207

Query: 334  LGMVVIADLSTDPTELEERALE----VAGPDGQASAISPASPRRKAADGGHR-------R 382
             G+  I      P    E        V GP G   +  PA    K   G          +
Sbjct: 1208 -GLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQ 1266

Query: 383  ALPGCTSL-----TGETTGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGA--GDS 435
             LPG          G   GE G  GQ G P    L G      L    G   +    GD 
Sbjct: 1267 GLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDP 1326

Query: 436  G-HASPDTGPCVNQKQEPGPAQEEAELG 462
            G    P           PG A  E E G
Sbjct: 1327 GLPGVPGFPGMKGPSGVPGSAGPEGEPG 1354



 Score = 34.3 bits (77), Expect = 0.36
 Identities = 74/282 (26%), Positives = 90/282 (31%), Gaps = 74/282 (26%)

Query: 222 PETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGA----GLPGGPQEEGD--- 274
           P    +PG  G    L     +GEK   GA    G     GA    G PG   E GD   
Sbjct: 493 PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT 552

Query: 275 --------------GVPCTPASAPTSGP--APGL-GPASWCLEPGSVA-QGSPDPQQTPS 316
                         G P  P    T G    PGL GP     EPG +  +G   P   P 
Sbjct: 553 FPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKG---EPGGITFKGERGPPGNPG 609

Query: 317 RMGREGEGTHSSLGCSSLGMVVIADLSTDPTELEERALE-VAGPDGQASAISPASPRRKA 375
             G  G      +G    G          P  + E+ ++ VAG  GQ             
Sbjct: 610 LPGLPGN--IGPMGPPGFG---------PPGPVGEKGIQGVAGNPGQPG----------- 647

Query: 376 ADGGHRRALPGCTSLTGETTGESGEAGQDGKP--------PGDVLVGPTASLALAPGS-G 426
                   +PG     G+T  + G+ G  G P        PGD  +     L   PGS G
Sbjct: 648 --------IPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKG 699

Query: 427 E-SMMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELGGQNLE 467
           E  + G G  G   P   P +     PGP       G   LE
Sbjct: 700 EPGIPGIGLPGPPGPKGFPGI-----PGPPGAPGTPGRIGLE 736


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 108/451 (23%), Positives = 146/451 (32%), Gaps = 60/451 (13%)

Query: 49   KLGPVPSTQQHGEEPGKAVSSSPDEETGSPCRLLRQPEKEPAPLPPSQNSFGRFVPQFAK 108
            K GP PS+        +    S   E  SP   L +P     PLPP     G   PQF  
Sbjct: 3478 KAGPKPSSLSMAHSRVRPPMRSQASEEESPVSPLGRPRPAGGPLPPG----GDTCPQFCS 3533

Query: 109  SRKTVTRKEEMKDEDRGSGAFSLETIAESSAQSPGCQLLVETLGVPLQEATELGD-PTQA 167
            S      +E +KD  R       E      +           LG   QE T+  D P  A
Sbjct: 3534 SHSMPDVQEHVKDGPRAHAYKREEGYILDDSHCVVSDSEAYHLG---QEETDWFDKPRDA 3590

Query: 168  DSARPEQ------SSQSPVQAVPGSGDSQPDDPPDRG-----TGLSASQRASQDHLSEQG 216
             S R         SS S  +          D+PP+ G      G      ++++H     
Sbjct: 3591 RSDRFRHHGGHAVSSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHGDH 3650

Query: 217  ADDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGV 276
               S   T   PG    K H   +   G    R   Q   A      G PG P       
Sbjct: 3651 GRHSGRHTGEEPGRRAAKPHARDL---GRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQ 3707

Query: 277  PCTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGRE-GEGTHSSLGCSSLG 335
            P   +SA         G       P ++ Q   +PQ  P   GR+   G   S   SS  
Sbjct: 3708 PSRASSAYHHASDSKKGSRQAHSGPAAL-QSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQ 3766

Query: 336  MVVIADLSTDPTELEERALEVAGPD---GQASAISPASPRRK----AADGGHRRALPGCT 388
            +   A      T+ +++ L +  P     QA     + P  +    AA     +  PG +
Sbjct: 3767 IPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPS 3826

Query: 389  SLTG----------ETTGESG--EAGQDGKPPGDVLVGPTASLALAPGSGESMMGAGDSG 436
            + TG          +T G  G  +A Q G+ P             APG G + + AG   
Sbjct: 3827 TATGPQPAGPPRAEQTNGSKGTAKAPQQGRAP---------QAQPAPGPGPAGVKAGARP 3877

Query: 437  HASPDT--------GPCVNQKQEPGPAQEEA 459
              +P          G  V  K  PG A E+A
Sbjct: 3878 GGTPGAPAGQPGADGESVFSKILPGGAAEQA 3908



 Score = 37.4 bits (85), Expect = 0.043
 Identities = 25/74 (33%), Positives = 28/74 (37%), Gaps = 7/74 (9%)

Query: 244 GEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPASAPTSGPAPGLGPASWCLEP-- 301
           G  P  G P    A    G  LP         VP  P   P  GP PG G  S  L+P  
Sbjct: 28  GPGPGAGKPPSAPA---GGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPGSTSRRLDPKE 84

Query: 302 --GSVAQGSPDPQQ 313
             G+    SP P+Q
Sbjct: 85  PLGNQRAASPTPKQ 98



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 55/205 (26%), Positives = 72/205 (35%), Gaps = 35/205 (17%)

Query: 118 EMKDEDRGSGAFSLETIAESSAQSPGCQLLVETLGVPLQE-------------------A 158
           +M    R      L + A S A SP  Q     LG P QE                   A
Sbjct: 229 DMTTAPRSKSQQQLHSPALSPAHSPAKQ----PLGKPDQERSRGPGGPQPGSRQAETARA 284

Query: 159 TELGDPTQADSARPEQSSQSPVQAVPGSGDSQPDDPPDRGTGLSASQRASQDHLSEQGAD 218
           T +  P QA +A PE    SP    P    +    PP  G   + S  A    L   GA 
Sbjct: 285 TSVPGPAQA-AAPPEVGRVSPQPPQPTKPSTAEPRPP-AGEAPAKSATAVPAGL---GAT 339

Query: 219 DSKPE--TDRVPGDGG----QKEHLPSIDSEGEKPDRGAPQEGGAQRTAG-AGLPGGPQE 271
           +   E  T ++ G G     Q   L S+  E +   + AP +G  +     A    GP+ 
Sbjct: 340 EQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKP 399

Query: 272 EGDGVPCTPASAPTSGPAPGLGPAS 296
            G G    PA    + P   +GP S
Sbjct: 400 LGSGPGPGPAPGAKTEPGARMGPGS 424



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 48/221 (21%), Positives = 73/221 (33%), Gaps = 43/221 (19%)

Query: 49  KLGPVPSTQQ------HGEEPGKAVSSSPDEETGSPCRLLRQPEKEPAPLPPSQNSFGRF 102
           K  P+PS            EP K  SS  +++T  P +       EP P PP + +    
Sbjct: 578 KASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKA------EPMPKPPPETT---P 628

Query: 103 VPQFAKSRKTVTRKE-------EMKDEDRGSGAFSL-------------ETIAESSAQSP 142
            P   K +  V R E        + +  +G  A  L             ++++++   S 
Sbjct: 629 TPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTGYSSD 688

Query: 143 G-CQLLVETLGVPLQEATELGD-------PTQADSARPEQSSQSPVQAVPGSGDSQPDDP 194
           G      E  GV  QE  +L         P          SS  P+    G   S+   P
Sbjct: 689 GISSSQSEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGSSMRPLLQAQGLAPSERSKP 748

Query: 195 PDRGTGLSASQRASQDHLSEQGADDSKPETDRVPGDGGQKE 235
              GTG    QR     ++ +  D  +   D +  D    E
Sbjct: 749 LSSGTGEEQKQRPHSLSITPEAFDSDEELEDILEEDEDSAE 789


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 74/258 (28%), Positives = 96/258 (37%), Gaps = 45/258 (17%)

Query: 218  DDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDG-V 276
            +  KP  D +PG  GQK               G P + G       GLPG   ++GDG +
Sbjct: 1165 EKGKPGQDGIPGPAGQK---------------GEPGQPGFGNPGPPGLPGLSGQKGDGGL 1209

Query: 277  PCTPASAPTSGPA--------PGL-GPASWCLEPGSVAQG---SPDPQQTPSRMGREG-E 323
            P  P +    GP         PG+ GP      PG   +G   +P PQ  P R G  G +
Sbjct: 1210 PGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQ 1269

Query: 324  GTHSSLGCSSL-GMVVIADLSTDPTELEERALEVA----GPDGQASAISPASPRRKAADG 378
            G     G   L G   I     +P +     L       GP G     +P  P      G
Sbjct: 1270 GLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQG--NPGRPGLNGMKG 1327

Query: 379  GHRRALPGCTSLTGET--TGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGAGDSG 436
                 LPG     G    +G  G AG +G+P    L+GP     L   SG+S++  GD+G
Sbjct: 1328 DP--GLPGVPGFPGMKGPSGVPGSAGPEGEPG---LIGPPGPPGLPGPSGQSIIIKGDAG 1382

Query: 437  HASPDTGPCVNQKQEPGP 454
                   P    K  PGP
Sbjct: 1383 PPGIPGQP--GLKGLPGP 1398



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 86/319 (26%), Positives = 110/319 (34%), Gaps = 72/319 (22%)

Query: 162 GDPTQ-ADSARP-EQSSQSPVQAVPGSGDSQPDDPPD-RGT----GLSASQRASQDHLSE 214
           G P Q ++  RP +   Q   Q +PG  D  P  PP  RG     G    ++  Q    +
Sbjct: 239 GPPGQISEQKRPIDVEFQKGDQGLPG--DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGK 296

Query: 215 QG-----ADDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQ----------- 258
           +G      ++ +P    +PGD G          +G+K D G P   G             
Sbjct: 297 RGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIG 356

Query: 259 RTAGAGLPGGPQEEGD-GVPCTPASAPTSGPAPGL-GPASWCLEPGSVAQGSPDPQQTPS 316
                GLPG P E+G+ G P         GP PGL GP      PG+   G P P   P 
Sbjct: 357 EKGNIGLPGLPGEKGERGFP------GIQGP-PGLPGP------PGAAVMGPPGPPGFPG 403

Query: 317 RMGREGEGTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAA 376
             G++G+      G   + +     L   P      A  + GP G A    P S      
Sbjct: 404 ERGQKGDE-----GPPGISIPGPPGLDGQP-----GAPGLPGPPGPAGPHIPPSDEICEP 453

Query: 377 DGGHRRALPGCTSLTGET---------------TGESGEAGQDGKPPGDVLVGPTASLAL 421
                   PG   L GE                TG SG  GQ G P    L GP  SL  
Sbjct: 454 GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPG---LPGPPGSLGF 510

Query: 422 APGSGESMMGAGDSGHASP 440
               GE     G +G   P
Sbjct: 511 PGQKGEK----GQAGATGP 525



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 73/271 (26%), Positives = 94/271 (34%), Gaps = 51/271 (18%)

Query: 244  GEKPDRGAPQEGGAQRTAGAGLPGGPQEEG-DGVPCTPASAPTSGPAPGLGPASWCLEPG 302
            G K DRG P           G PG P   G DG+P        +G    +GP      PG
Sbjct: 772  GPKGDRGFP-----------GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL---PG 817

Query: 303  SVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQ 362
               QG P P   P  +G+ G                +  +  +  +     L+V GP G+
Sbjct: 818  IGVQGPPGPPGIPGPIGQPG----------------LHGIPGEKGDPGPPGLDVPGPPGE 861

Query: 363  -ASAISPASPRRKAADGGHRRALPGCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLAL 421
              S   P +P      G     LPG    +G   G  GE G  G P      GP   L +
Sbjct: 862  RGSPGIPGAPGPIGPPGS--PGLPGKAGASG-FPGTKGEMGMMGPP------GPPGPLGI 912

Query: 422  APGSGESMMGAGDSGHASPD-TGPC--VNQKQEPG----PAQEEAELGGQNLERDLEGFR 474
               SG   +   D     P   GP      K EPG    P   +  L G   E+   G  
Sbjct: 913  PGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLP 972

Query: 475  VSPQASVVLEHREIADDPLQEPG--AQQGIP 503
              P  S    ++ +  DP Q PG   Q G+P
Sbjct: 973  GIPGVSGPKGYQGLPGDPGQ-PGLSGQPGLP 1002



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 61/232 (26%), Positives = 79/232 (34%), Gaps = 45/232 (19%)

Query: 227  VPGDGGQKEH--------LPSIDSEGEKPDRGAPQ-EGGAQRTAGAGLPGGPQEEGDGVP 277
            +PG+GG K          LP +   G K D+G P  +G   R    G+ G P     G+P
Sbjct: 1280 LPGNGGIKGEKGNPGQPGLPGLP--GLKGDQGPPGLQGNPGRPGLNGMKGDP-----GLP 1332

Query: 278  CTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMV 337
              P      GP+   G A    EPG +  G P P   P              G S   ++
Sbjct: 1333 GVPGFPGMKGPSGVPGSAGPEGEPGLI--GPPGPPGLP--------------GPSGQSII 1376

Query: 338  VIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGET--- 394
            +  D        +     + GP G      P  P     D G R  LPG     G     
Sbjct: 1377 IKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGP---PGDPG-RNGLPGFDGAGGRKGDP 1432

Query: 395  --TGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGP 444
               G+ G  G DG P  D L GP       PG+     G   + H+     P
Sbjct: 1433 GLPGQPGTRGLDGPPGPDGLQGPPG----PPGTSSVAHGFLITRHSQTTDAP 1480



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 89/334 (26%), Positives = 108/334 (32%), Gaps = 58/334 (17%)

Query: 172 PEQSSQSPVQAVPGSGDSQPDDPPDRGT-GLSASQRASQDHLSEQGADDSKPETDRVPGD 230
           P    +  +Q V G+   QP  P  +G  G + +Q          G D        +PGD
Sbjct: 628 PGPVGEKGIQGVAGN-PGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVG----LPGD 682

Query: 231 GGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEG-------DGVPCTPASA 283
            G    LP     G+    G P   G     G GLPG P  +G        G P TP   
Sbjct: 683 PG----LP-----GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRI 733

Query: 284 PTSGP--APGL-GPASWCLEPGSVAQGSPDPQQTPSRMGREG----------EGTHSSLG 330
              GP   PG  GP     EPG    G P P   P   G  G           G     G
Sbjct: 734 GLEGPPGPPGFPGPKG---EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTG 790

Query: 331 CSSL-GMVVIADLSTDPTELEERALE---VAGPDGQASAISP-ASPRRKAADGGHRRALP 385
              L G       +  P  +    L    V GP G      P   P      G   +  P
Sbjct: 791 LDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPG--EKGDP 848

Query: 386 GCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGA--GDSGHASPDTG 443
           G   L  +  G  GE G  G P     +GP  S  L   +G S      G+ G   P  G
Sbjct: 849 GPPGL--DVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP-PG 905

Query: 444 PCVNQKQEPGPAQEEAELGGQNLERDLEGFRVSP 477
           P       PGP       G   L+ D +G +  P
Sbjct: 906 P-------PGPLGIPGRSGVPGLKGD-DGLQGQP 931



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 70/271 (25%), Positives = 80/271 (29%), Gaps = 41/271 (15%)

Query: 218  DDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVP 277
            D   P     PG  GQ    P +      P    P+ G +      GLPG P   G G  
Sbjct: 1102 DPGLPGLPGTPGAKGQ----PGLPGFPGTPGPPGPK-GISGPPGNPGLPGEPGPVGGGGH 1156

Query: 278  CTPASAPTSGPAPGL----GPASWCLEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSS 333
                  P     PG     GPA    EPG    G+P P   P   G++G+G         
Sbjct: 1157 PGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDG--------- 1207

Query: 334  LGMVVIADLSTDPTELEERALE----VAGPDGQASAISPASPRRKAADGGH-RRALPGCT 388
             G+  I      P    E        V GP G   +  PA    K   G       PG T
Sbjct: 1208 -GLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPT 1266

Query: 389  SL--------------TGETTGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGA-- 432
                             G   GE G  GQ G P    L G      L    G   +    
Sbjct: 1267 GFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMK 1326

Query: 433  GDSG-HASPDTGPCVNQKQEPGPAQEEAELG 462
            GD G    P           PG A  E E G
Sbjct: 1327 GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPG 1357



 Score = 34.3 bits (77), Expect = 0.36
 Identities = 74/282 (26%), Positives = 90/282 (31%), Gaps = 74/282 (26%)

Query: 222 PETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGA----GLPGGPQEEGD--- 274
           P    +PG  G    L     +GEK   GA    G     GA    G PG   E GD   
Sbjct: 493 PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT 552

Query: 275 --------------GVPCTPASAPTSGP--APGL-GPASWCLEPGSVA-QGSPDPQQTPS 316
                         G P  P    T G    PGL GP     EPG +  +G   P   P 
Sbjct: 553 FPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKG---EPGGITFKGERGPPGNPG 609

Query: 317 RMGREGEGTHSSLGCSSLGMVVIADLSTDPTELEERALE-VAGPDGQASAISPASPRRKA 375
             G  G      +G    G          P  + E+ ++ VAG  GQ             
Sbjct: 610 LPGLPGN--IGPMGPPGFG---------PPGPVGEKGIQGVAGNPGQPG----------- 647

Query: 376 ADGGHRRALPGCTSLTGETTGESGEAGQDGKP--------PGDVLVGPTASLALAPGS-G 426
                   +PG     G+T  + G+ G  G P        PGD  +     L   PGS G
Sbjct: 648 --------IPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKG 699

Query: 427 E-SMMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELGGQNLE 467
           E  + G G  G   P   P +     PGP       G   LE
Sbjct: 700 EPGIPGIGLPGPPGPKGFPGI-----PGPPGAPGTPGRIGLE 736


>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
          Length = 684

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 89/327 (27%), Positives = 109/327 (33%), Gaps = 58/327 (17%)

Query: 181 QAVPGSGDSQPDDPPDRGTGLSASQRASQDHLSEQGADDSKPETDRVPGDGGQKEHLPSI 240
           Q V   G   P  PP +         A    L         P     PG+ G    LP +
Sbjct: 26  QRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPG-LPGV 84

Query: 241 DS----EGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPASAPTSGPAPGL---G 293
           D     +G    +GAP E G+      G PG P   G G+P  P  A  SGP  G+   G
Sbjct: 85  DGLTGRDGPPGPKGAPGERGS-----LGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRG 139

Query: 294 PASWCLEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSSL---------GMVVIADLST 344
           P      PG    G P P   P   G   EG  + L C S+         GM        
Sbjct: 140 PPGPSGLPG--LPGPPGPPGPPGHPGVLPEGA-TDLQCPSICPPGPPGPPGMPGF----K 192

Query: 345 DPTELEERALEVAGPDGQASAISPASPRRKAADGGHR-----RALPGCTSLTGE------ 393
            PT  +    EV G DG+     P  P       G +     R LPG     G+      
Sbjct: 193 GPTGYKGEQGEV-GKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGF 251

Query: 394 -----------TTGESGEAGQDG--KPPGDV-LVGPTASLALAPGSGESMMGAGDSGHAS 439
                        G+ GE G +G   P GD+   GP  +  +A  SGE  M   D  +  
Sbjct: 252 RGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGV 311

Query: 440 PDTGPCVNQKQEPGPAQEEAELGGQNL 466
           P       QK E G      E G   L
Sbjct: 312 PGLD---GQKGEAGRNGAPGEKGPNGL 335



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 85/340 (25%), Positives = 116/340 (34%), Gaps = 52/340 (15%)

Query: 191 PDDPPDRGTGLSASQRASQDHLSEQG--ADDSKPETDRVPGDGGQKEHLPSIDSEGEKPD 248
           P  P   G+     +R     L E G   +   P    +PG+ G+  H  S  + G +  
Sbjct: 336 PGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGP 395

Query: 249 RGAPQEGGAQRTAGA----GLPGGPQEEGDGVPCTPASAPTSGPAPGLGPASWCLEPGSV 304
            GAP   G Q   G+    GLPG     GD     P  A  +GP    G A     PG  
Sbjct: 396 PGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGA--AGPKGDQGIAGSDGLPGDK 453

Query: 305 AQGSPDPQQTP-SRMGREGE----GTHSSLGCSSLGMVVIADLSTDPTELEERALE-VAG 358
            +  P     P    G  GE    GT    G S      +  +   P  L  + +  V G
Sbjct: 454 GELGPSGLVGPKGESGSRGELGPKGTQGPNGTSG-----VQGVPGPPGPLGLQGVPGVPG 508

Query: 359 PDGQASAISPASPRRKAADGGHRRALPGCTS-------------LTGETTGESGEAGQDG 405
             G+     P  P ++A++   R    G  S             L   + G  G AG  G
Sbjct: 509 ITGK-----PGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPG 563

Query: 406 KPPGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELGGQN 465
            P      GP  S+   PG+       G +G    D GP  NQ          A L G  
Sbjct: 564 PP------GPPGSIG-HPGARGPPGYRGPTGELG-DPGPRGNQGDRGDKGAAGAGLDGPE 615

Query: 466 LERDLEGFRVSPQASVVLEHREIADDPLQEPG--AQQGIP 503
            ++  +G +  P  S     ++  D    EPG     G+P
Sbjct: 616 GDQGPQGPQGVPGTS-----KDGQDGAPGEPGPPGDPGLP 650



 Score = 37.0 bits (84), Expect = 0.056
 Identities = 56/207 (27%), Positives = 68/207 (32%), Gaps = 30/207 (14%)

Query: 227 VPGDGGQKEHLPSIDSEGEKPDRGAP-------------QEGGAQRTAGAGLPGGPQEEG 273
           VPG  GQK       + GEK   G P             + G A     AG  G P   G
Sbjct: 311 VPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPG 370

Query: 274 D-GVPCTPASAPTSGPAPGLGPASWCLEPGSVA----------QGSPDPQQTPSRMGREG 322
           D G+P     A   G A  LGP      PG              G P PQ     +G  G
Sbjct: 371 DAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRG 430

Query: 323 EGTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADGGHR- 381
            G  +       G+     L  D  EL    L   GP G++ +     P+      G   
Sbjct: 431 PGGAAG-PKGDQGIAGSDGLPGDKGELGPSGL--VGPKGESGSRGELGPKGTQGPNGTSG 487

Query: 382 -RALPGCTSLTGETTGESGEAGQDGKP 407
            + +PG     G   G  G  G  GKP
Sbjct: 488 VQGVPGPPGPLG-LQGVPGVPGITGKP 513



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 54/205 (26%), Positives = 74/205 (36%), Gaps = 38/205 (18%)

Query: 142 PGCQLLVETLGVPLQEATELGDPTQADSARPEQSSQSPVQA----VPGS----GDSQPDD 193
           PG   +    GVP +EA+E            EQ +Q          PGS    G + P  
Sbjct: 504 PGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPG 563

Query: 194 PPDRGTGLSASQRASQDHLSEQGADDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQ 253
           PP            S  H   +G    +  T  + GD G +       ++G++ D+GA  
Sbjct: 564 PP--------GPPGSIGHPGARGPPGYRGPTGEL-GDPGPR------GNQGDRGDKGA-- 606

Query: 254 EGGAQRTAGAGLPGGPQEEG----DGVPCTPASAPTSGPAPGLGPASWCLEPGSV-AQGS 308
                  AGAGL G   ++G     GVP T        P    GP      PG++ AQG+
Sbjct: 607 -------AGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEP-GPPGDPGLPGAIGAQGT 658

Query: 309 PDPQQTPSRMGREGEGTHSSLGCSS 333
           P    T +  G    G     G  S
Sbjct: 659 PGICDTSACQGAVLGGVGEKSGSRS 683


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 73/265 (27%), Positives = 96/265 (36%), Gaps = 41/265 (15%)

Query: 227  VPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQ-------EEGD----G 275
            +PG  G +  +     +G + +RG P   G     G   P GP        EEGD    G
Sbjct: 1023 LPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVG 1082

Query: 276  VPCTPASAPTSGPA-----PGL-GPASWCLEPGSVAQGSPDPQQTPSRMGREGE-GTHSS 328
             P    S    G A     PG+ GPA     PG  A G+   +  P   G++G+ G    
Sbjct: 1083 APGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPG--ADGAQGRRGPPGLFGQKGDDGVRGF 1140

Query: 329  LGCSSLGMVVIADLSTDPTELEERA-LEVAGPDGQASAISPASPRRKAADGGHRRALPGC 387
            +G   +G   +  L   P E  E   +   GP G      P  P       G    LPG 
Sbjct: 1141 VGV--IGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPG----LPGG 1194

Query: 388  TSLTGET--TGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGPC 445
                G     GE G+AG  G P    + GP   +      G+S    G SG A P     
Sbjct: 1195 VGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIG---EKGDS----GPSGAAGPP---- 1243

Query: 446  VNQKQEPGPAQEEAELGGQNLERDL 470
              +K  PG    +  +G   L  DL
Sbjct: 1244 -GKKGPPGEDGAKGSVGPTGLPGDL 1267



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 102/408 (25%), Positives = 130/408 (31%), Gaps = 79/408 (19%)

Query: 154  PLQEATELGDPTQADSARP--------EQSSQSPVQAVPGSGD-SQPDDPPDRGTGLSAS 204
            P  +  E GD   + +A P        E  ++  V      GD   P DP   G   S  
Sbjct: 1224 PKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPG 1283

Query: 205  QRASQDHLSEQGADDS--KPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAG 262
            ++     +   G   +  +P     PG  G   H+     EGEK  +G P          
Sbjct: 1284 EKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEP---------- 1333

Query: 263  AGLPGGPQEEGDGVPCTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREG 322
                 GP    DG P         GP   +GP      PG V  G P     P +MG  G
Sbjct: 1334 -----GP----DGPPGRTGPMGARGPPGRVGPEGLRGIPGPV--GEPGLLGAPGQMGPPG 1382

Query: 323  EGTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADGGHRR 382
                       LG   +  L  D     E+     G  G    I P     +  D G   
Sbjct: 1383 ----------PLGPSGLPGLKGDTGPKGEK-----GHIGLIGLIGPPGEAGEKGDQG--- 1424

Query: 383  ALPGCTSLTGE--TTGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGAGDSGHASP 440
             LPG     G     G  G  G  G P    + GP      + GS  SM   GD+G A P
Sbjct: 1425 -LPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKG-SKGSPGSMGPRGDTGPAGP 1482

Query: 441  DTGPCVNQKQEPGPAQEEAELGGQNLERD--------LEGFRVSPQASVVLEHREIADDP 492
                       PGP    AEL G    R         +EG      AS+     E+ +  
Sbjct: 1483 -----------PGPPGAPAELHGLRRRRRFVPVPLPVVEGGLEEVLASLTSLSLEL-EQL 1530

Query: 493  LQEPGAQQGIPDTTSELAGQRDHLPH-----SADQGTWADSLAVELDF 535
             + PG  +       EL     HLP        +QG   DS  V  +F
Sbjct: 1531 RRPPGTAERPGLVCHELHRNHPHLPDGEYWIDPNQGCARDSFRVFCNF 1578



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 75/272 (27%), Positives = 92/272 (33%), Gaps = 54/272 (19%)

Query: 219 DSKPETDR-------VPGDGGQKE---HLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPG- 267
           D+ P+ DR       +PG+ GQ+    H+      GE  +RGA  EG    T  AG PG 
Sbjct: 543 DTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGA--EGPPGPTGQAGEPGP 600

Query: 268 ----GPQEEGD--------GVPCTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQ-- 313
               GP+            G+   P +    GP    GP       GS  QG P PQ   
Sbjct: 601 RGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGS--QGLPGPQGLI 658

Query: 314 -TPSRMGREGEGTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQASAISPASPR 372
            TP   G  G      L  S         L     E         GP G A       PR
Sbjct: 659 GTPGEKGPPGNPGIPGLPGSD------GPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPR 712

Query: 373 RKAADGGHRRALPGCTSLTGETTGESGEAGQDGKP--PGDVLVGPTASLALAPGSGESMM 430
                 G+R              GE GE G+DG P   GDV +        APG      
Sbjct: 713 GVKGTSGNRGL-----------QGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDG 761

Query: 431 GAGDSGHASPDTGPCVNQKQEPGPAQEEAELG 462
             G  G A         ++  PG A E+ +LG
Sbjct: 762 PEGPKGQAGQ-----AGEEGPPGSAGEKGKLG 788



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 81/298 (27%), Positives = 95/298 (31%), Gaps = 48/298 (16%)

Query: 228  PGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPASAPTSG 287
            PGD G           G K D+G P   GA  + G   P GP   G G+P    S    G
Sbjct: 985  PGDPGPT---------GLKGDKGPPGPVGANGSPGERGPLGP-AGGIGLPGQSGSEGPVG 1034

Query: 288  PAPGLGPASWCLEPGSVAQ----GSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIADLS 343
            PA   G       PG   +    G   P   P   G  GE                 D+ 
Sbjct: 1035 PAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDK------------GDVG 1082

Query: 344  TDPTELEERALEVAGPDGQASAISPAS-PRRKAADGGHRRALPGCTSLTGETTGESGEAG 402
                +  +     AGP GQ     PA  P    ADG   R  P          G  G+ G
Sbjct: 1083 APGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGP---------PGLFGQKG 1133

Query: 403  QDGKPPGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELG 462
             DG      ++GP     L PG        GD G   P   P    +   GP   E   G
Sbjct: 1134 DDGVRGFVGVIGPPGLQGL-PGPPGEKGEVGDVGSMGPHGAP--GPRGPQGPTGSEGTPG 1190

Query: 463  GQNLERDLEGFRVSPQASVVLEHREIADDPLQEPGAQQGIPDTTSELAGQRDHLPHSA 520
                   L G    P A      R  A DP   PGA  GIP    ++  + D  P  A
Sbjct: 1191 -------LPGGVGQPGAVGEKGERGDAGDP-GPPGA-PGIPGPKGDIGEKGDSGPSGA 1239



 Score = 37.4 bits (85), Expect = 0.043
 Identities = 56/230 (24%), Positives = 72/230 (31%), Gaps = 43/230 (18%)

Query: 229  GDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGA-GLPGGPQEEG-DGVPCTPASAPTS 286
            G  G+K         G + +RG P   G +   GA G PG   + G DG P  P      
Sbjct: 812  GPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGL- 870

Query: 287  GPAPGL-GPASWCLEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIADLSTD 345
               PGL GP            G P P+  P   G++G   H                   
Sbjct: 871  ---PGLQGPP-----------GFPGPKGPPGHQGKDGRPGH------------------- 897

Query: 346  PTELEERALE-VAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGETTGESGEAGQD 404
            P +  E   +   GP G A  + P     +    G R   PG         GE G  G +
Sbjct: 898  PGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGP-PGPPG----PPGEQGLPGLE 952

Query: 405  GKPPGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGP 454
            G+      +GP   L     +G         G   P        K  PGP
Sbjct: 953  GREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGP 1002


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein
           [Homo sapiens]
          Length = 1629

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 127/473 (26%), Positives = 162/473 (34%), Gaps = 88/473 (18%)

Query: 40  LHHPE--EPEGKL--GPVPSTQQHGE----EPGKAVSSSPDEETGSPCRLLRQP--EKEP 89
           LH P+  EP+ +   GP     + GE    EPG  V   P  E   P  L+  P  +  P
Sbjct: 255 LHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPE--GPAGLIGPPGIQGNP 312

Query: 90  APL--PPSQNSFGRFVPQFAKSRKTVTRKEEMKDEDRGSGAFSLETIAESSAQSPGCQLL 147
            P+  P  +   GR     +           M     GSG      +   +AQ    Q +
Sbjct: 313 GPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVV--AAQEAQAQAI 370

Query: 148 VETLGVPLQEATELGDP-TQADSARPEQSSQSPVQAVPG-SGDSQPDDPPDRGTGLSASQ 205
           ++   + L+     G P     + RP    Q     + G SGD  P  P  RG       
Sbjct: 371 LQQARLALR-----GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGP--RGPQGLTGP 423

Query: 206 RASQDHLSEQGADDSKPETDRVPGDGGQK-----EHLPSIDSEGEKPDRGAPQEGGAQRT 260
                     GAD ++     +PGD G K     + LP +   GEK  RG   + GAQ  
Sbjct: 424 PGKAGRRGRAGADGARG----MPGDPGVKGDRGFDGLPGLP--GEKGHRG---DTGAQ-- 472

Query: 261 AGAGLPGGPQEE---GDGVPCTPASAP-TSGPAPGLGPASWCLEPGSVA----------- 305
              GLPG P E+   GD     P   P  SGP   LGP      PG              
Sbjct: 473 ---GLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPK 529

Query: 306 -----QGSPDP---QQTPSRMGREGE----GTHSSLGCSSLGMVVIADLSTDPTELEERA 353
                QG P P   Q TP   G  G     G H   G      +     S  P     + 
Sbjct: 530 GSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGK- 588

Query: 354 LEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGETTGESGEAGQDGKP--PGDV 411
               GP G      P+ P+      G  R + G   + G   G  GE G+DG P   GD+
Sbjct: 589 ---EGPPGTKGNQGPSGPQGPLGYPG-PRGVKGVDGIRG-LKGHKGEKGEDGFPGFKGDI 643

Query: 412 LVGPTASLALAPGSGESMMGAGDSGHASP--DTGPCVNQKQEPGPAQEEAELG 462
            V         PGS       G  G   P  D GP       PG   E+ +LG
Sbjct: 644 GVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP-------PGLMGEKGKLG 689



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 74/263 (28%), Positives = 90/263 (34%), Gaps = 67/263 (25%)

Query: 228  PGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAG-------------AGLPGGPQEEGD 274
            PG  G++    +   EG K D G P   G    AG             AG PG    EG 
Sbjct: 841  PGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGP 900

Query: 275  GVPCTPASAPTSGPAPGLGPASWCLEPGSVA-QGSPDPQQTPSRMGREG-EGTHSSLGCS 332
              P  PA +P    A G G        G +   G P PQ  P   G +G  G    +G  
Sbjct: 901  SGPPGPAGSPGERGAAGSG--------GPIGPPGRPGPQGPPGAAGEKGVPGEKGPIG-- 950

Query: 333  SLGMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADGGHRRAL--PGCTSL 390
                         PT  +       G  G      PA P   A + G +  +  PG    
Sbjct: 951  -------------PTGRD-------GVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKG- 989

Query: 391  TGETTGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGA-GDSGH--ASPDTGP--- 444
               T G  GE G  G PPG   +GP      A   GE   GA G  GH  A  D G    
Sbjct: 990  ---TKGNKGEHGPPG-PPGP--IGPVGQPGAAGADGEP--GARGPQGHFGAKGDEGTRGF 1041

Query: 445  -----CVNQKQEPGPAQEEAELG 462
                  +  +  PGP+ E+ E G
Sbjct: 1042 NGPPGPIGLQGLPGPSGEKGETG 1064



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 99/387 (25%), Positives = 126/387 (32%), Gaps = 88/387 (22%)

Query: 142  PGCQLLVETLGVPLQEATELGDPTQADSARPEQSSQSPVQAVPGS-------------GD 188
            PG Q L  T G   +E T+ GDP       P +   + ++  PG              G+
Sbjct: 844  PGEQGLPGTAG---KEGTK-GDP--GPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 897

Query: 189  SQPDDPPDRGTGLSASQRASQDHLSEQGADDSKPETDRVPGDGGQKEHLPSIDSEGEKPD 248
              P  PP  G   S  +R +       G    +P     PG  G+K         GEK  
Sbjct: 898  EGPSGPP--GPAGSPGERGAAGSGGPIGPP-GRPGPQGPPGAAGEK------GVPGEKGP 948

Query: 249  RGAPQEGGAQRTAG----AGLPGGPQEEGD-------GVPCTPASAPTSGPAPGLGPASW 297
             G     G Q   G    AG PG   E+GD       G   T  +    GP    GP   
Sbjct: 949  IGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGP 1008

Query: 298  CLEPGSV-AQGSPDPQQTPSRMGREG-EGTHSSLGCSS-LGMVVIADLSTDPTELEERAL 354
              +PG+  A G P  +      G +G EGT    G    +G+  +   S +  E  +  +
Sbjct: 1009 VGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGD--V 1066

Query: 355  EVAGPDGQASAISPASPRRKAADG--------------GHR-----------RALPGCTS 389
               GP G      PA P    ADG              G +           +  PG   
Sbjct: 1067 GPMGPPGPPGPRGPAGPN--GADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKG 1124

Query: 390  LTGETTGESGEAGQDGKPPGDVLVGPTASLAL--------------APGSGESMMGAGDS 435
              GE  GE GE+GQ G+P      GPT                    PG G      G  
Sbjct: 1125 PRGER-GEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAK 1183

Query: 436  GHASPDTGPCVNQKQEPGPAQEEAELG 462
            G    D  P   Q   PGP  E    G
Sbjct: 1184 GDRGEDGEP--GQPGSPGPTGENGPPG 1208



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 76/271 (28%), Positives = 97/271 (35%), Gaps = 60/271 (22%)

Query: 228  PGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPASAPTSG 287
            PG+ G+     S   +GE   +G   E G +  +G   PG P     G P         G
Sbjct: 1102 PGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQ--PGEP-----GPPGPKGPTGDDG 1154

Query: 288  PAPGLGPASWCLEPGSVAQGSPDPQQ-TPSRMGREGE-GTHSSLGCSSLGMVVIADLSTD 345
            P    GP  +  +PG   +G P  Q       G +GE G   S G +          +  
Sbjct: 1155 PKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTG--------ENGP 1206

Query: 346  PTELEERALEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGETTGESGEAGQDG 405
            P  L +R     GP G     SP S  R+   G   +  PG     G+ TG  G AG  G
Sbjct: 1207 PGPLGKR-----GPAG-----SPGSEGRQGGKGA--KGDPGAIGAPGK-TGPVGPAGPAG 1253

Query: 406  KPPGDVLVGPTASLALAPGSGESMMGAGDSGHASP--DTGP-----------CVNQKQEP 452
            KP  D L G        PGS       G +G A P    GP              +K  P
Sbjct: 1254 KPGPDGLRG-------LPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHP 1306

Query: 453  ------GPAQEEAELGGQNLERDLEGFRVSP 477
                  GP  E+ E G    +R L G + SP
Sbjct: 1307 GLIGLIGPPGEQGEKG----DRGLPGPQGSP 1333



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 78/287 (27%), Positives = 96/287 (33%), Gaps = 33/287 (11%)

Query: 183 VPGS-GDSQPDDPPDRGTGLSASQRASQDHLSEQGADDSKPETDRVPGDGGQKEHL--PS 239
           VPGS G+  P+ P  R TG +         L  +      P     PG  G K  L  P 
Sbjct: 654 VPGSRGEDGPEGPKGR-TGPTGDP--GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPG 710

Query: 240 ID-SEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPASAPTSGPAPGLGPASWC 298
              + GEK  RG   + G +   G   P G +        + A   + G  P   P    
Sbjct: 711 FPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG 770

Query: 299 LEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIADLSTDPTELEERALEVAG 358
           L       G P P+  P   G++G   H        G V     +  P         V G
Sbjct: 771 LPGPQGPNGFPGPKGPPGPPGKDGLPGHP----GQRGEVGFQGKTGPP-----GPPGVVG 821

Query: 359 PDGQASAISPASPRRKAADGGHRRALPGCTSLTGETTGESGEAGQDGKPPGDVLVGPTAS 418
           P G A    P   R      G     PG   L G T G+ G  G  G P      GP A 
Sbjct: 822 PQGAAGETGPMGERGHPGPPGP----PGEQGLPG-TAGKEGTKGDPGPPGAPGKDGP-AG 875

Query: 419 LALAPGS---GESMMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELG 462
           L   PG      +  G G  G+  P +GP       PGPA    E G
Sbjct: 876 LRGFPGERGLPGTAGGPGLKGNEGP-SGP-------PGPAGSPGERG 914



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 87/348 (25%), Positives = 117/348 (33%), Gaps = 79/348 (22%)

Query: 191  PDDPPDRGTGLSASQRASQDHLSEQGADDSKPET------DRVPGDGGQKEHLPSIDSEG 244
            P DP   G G    Q  ++    E G +  +P +      +  PG  G++    S  SEG
Sbjct: 1165 PGDPGPPGEGGPRGQDGAKGDRGEDG-EPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEG 1223

Query: 245  EKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPASAPTSGPAPGLGPASWCLEPGSV 304
             +  +GA  + GA    G   P GP                +GPA   GP      PGSV
Sbjct: 1224 RQGGKGAKGDPGAIGAPGKTGPVGP----------------AGPAGKPGPDGLRGLPGSV 1267

Query: 305  AQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQAS 364
             Q     Q  P   G+ G           +G   +  L  D     E+     G  G   
Sbjct: 1268 GQ-----QGRPGATGQAGPP-------GPVGPPGLPGLRGDAGAKGEK-----GHPGLIG 1310

Query: 365  AISPASPRRKAADGGHRRALPGCTSLTGE-----TTGESGEAGQDGKPPGDVLVGPT--- 416
             I P   + +  D    R LPG     G+       G SG  G  G PPG  L GP    
Sbjct: 1311 LIGPPGEQGEKGD----RGLPGPQGSPGQKGEMGIPGASGPIGPGG-PPG--LPGPAGPK 1363

Query: 417  -ASLALAPGSGESMMGA-GDSGHASPDTGPCVNQKQEPGPAQEEAELGGQNLERDLEGFR 474
             A  A  PG  +   G  G  GH  P       +  +P P Q       +   R ++G R
Sbjct: 1364 GAKGATGPGGPKGEKGVQGPPGHPGPP-----GEVIQPLPIQMP-----KKTRRSVDGSR 1413

Query: 475  VSPQASVVLEHREIADDPLQEPGAQQGIPDTTSELAGQRDHLPHSADQ 522
            +            + +D     G   G P    E+ G  D L    +Q
Sbjct: 1414 L------------MQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQ 1449



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 100/433 (23%), Positives = 136/433 (31%), Gaps = 87/433 (20%)

Query: 78  PCRLLRQPEKEPAPLPPSQNSFGRFVPQFAKSRKTVTRKEEMKDEDRGSGAFSLETIAES 137
           P R  R P+++P+ L   QN      PQ     +       +K E           + E 
Sbjct: 241 PHRAQRSPQQQPSRLHRPQNQ----EPQ----SQAAHGPRGLKGEKGEPAVLEPGMLVEG 292

Query: 138 SAQSPGCQLLVETLGV-----PLQEATELGDPTQA-----DSAR--PEQSSQSPVQAVPG 185
                G   L+   G+     P+ +  E G P +A     D A   P  S   P +   G
Sbjct: 293 PPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSG 352

Query: 186 SGDSQPDDPPDRGTGLSASQRASQDHLSEQGADDSKPETDRV-----PGDGGQKEHLPSI 240
            GD  P          +  Q+A    L+ +G       T R      PG  G K     +
Sbjct: 353 GGDKGPVVAAQEAQAQAILQQA---RLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 409

Query: 241 DSEGEKPDRGA---PQEGGAQRTAGA----GLPGGPQEEGD----GVPCTPASAPTSGPA 289
             +G +  +G    P + G +  AGA    G+PG P  +GD    G+P  P      G  
Sbjct: 410 GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDT 469

Query: 290 PGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIADLSTDPTEL 349
                          AQG P P       G +GE     +G   L           P E 
Sbjct: 470 G--------------AQGLPGPPGEDGERGDDGE-----IGPRGL-----------PGES 499

Query: 350 EERALEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGETTGESGEAGQDGKPPG 409
             R L   GP G      P   R      G + +L           GE G  GQ G P  
Sbjct: 500 GPRGL--LGPKGPPGIPGPPGVRGMDGPQGPKGSLG--------PQGEPGPPGQQGTPGT 549

Query: 410 DVLVGPTASLAL--------APGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQEEAEL 461
             L GP  ++           PG        G  GH   +  P     Q P   Q     
Sbjct: 550 QGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGY 609

Query: 462 GGQNLERDLEGFR 474
            G    + ++G R
Sbjct: 610 PGPRGVKGVDGIR 622


>gi|150418009 transforming, acidic coiled-coil containing protein 2
           isoform a [Homo sapiens]
          Length = 2948

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 138/591 (23%), Positives = 196/591 (33%), Gaps = 150/591 (25%)

Query: 44  EEPEGKLG--PVPSTQQHGEEPGKAVSSSPDEETGSPCRLLRQPEKEPAPLPPSQNSFGR 101
           E PEG  G  P PS Q+ GE     +++    E         QP   P PLP        
Sbjct: 480 EHPEGDPGEVPAPSPQERGEH----LNTEQSHEV--------QPGVPPPPLP-------- 519

Query: 102 FVPQFAKSRKTVTRKEEMKDEDRGSGAFSLETIAESSAQSPGCQLLVETLGVPLQEATEL 161
                         KE+  +   G+    L      SA+ P                   
Sbjct: 520 --------------KEQSHEVQPGAPPPPLPKAPSESARGP------------------- 546

Query: 162 GDPTQADSARPEQSSQSPVQAVPGS--------GDSQPDDPPDRGTGLSASQRASQDHLS 213
             P   D A+  + S SP  A  GS        G  +  +PPD G           D  +
Sbjct: 547 --PGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGG-----------DPGN 593

Query: 214 EQGADDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGP---- 269
            QG D     + R P  G  K+ L    S+ E  D  +       R  GAG   GP    
Sbjct: 594 LQGEDSQAFSSKRDPEVG--KDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQT 651

Query: 270 -QEEGDGVPCTPASA-PTSGPAPGLGPASWCLEPGSVAQGS------PDPQQTPSRMGRE 321
            + +  G+P       P   P P  G     +  G++ +GS      PD  Q+   +GR 
Sbjct: 652 AEADASGLPHKLGEEDPVLPPVPD-GAGEPTVPEGAIWEGSGLQPKCPDTLQSREGLGRM 710

Query: 322 GEGTHSSLGCSSLGMVVIADLSTDPTELEERALEV---AGPDGQASAISPASPRRKAADG 378
                     S      +A+++    E  E  LE+      DG+    SP  PR  A D 
Sbjct: 711 ESFLTLESEKSDFPPTPVAEVAPKAQE-GESTLEIRKMGSCDGEGLLTSPDQPRGPACDA 769

Query: 379 GHRRALPGCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLALAPGSGE----SMMGAGD 434
                             +   AG    P G+ L       AL     +    S  G G 
Sbjct: 770 SR----------------QEFHAGVPHPPQGENLAADLGLTALILDQDQQGIPSCPGEGW 813

Query: 435 SGHASPDTGPCVNQKQ-EPGPAQEEAEL------------GGQNLERDLEGFR----VSP 477
              A+ +     ++K  +P  AQ E  +             G+       GF+     S 
Sbjct: 814 IRGAASEWPLLSSEKHLQPSQAQPETSIFDVLKEQAQPPENGKETSPSHPGFKDQGADSS 873

Query: 478 QASVVLEHREIADDPLQEPGAQQGIPDTTSELAGQRDHLPHSADQGTWADS-LAVELDFL 536
           Q  V +E +E  D+ L   G Q+      SEL  Q   LP    +GT +D+  +   D +
Sbjct: 874 QIHVPVEPQE--DNNLPTHGGQE--QALGSELQSQ---LP----KGTLSDTPTSSPTDMV 922

Query: 537 LDSQIQDALDASDFEAPPEQLFPS-GNK--PGPCWPGPSSHANGDPVAVAK 584
            +S +    + S+  AP  Q  P+ G K   G C  G SS  +     V K
Sbjct: 923 WESSL---TEESELSAPTRQKLPALGEKRPEGACGDGQSSRVSPPAADVLK 970



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 129/585 (22%), Positives = 194/585 (33%), Gaps = 114/585 (19%)

Query: 20  LKNPRLGDFYGDPQSSMLGCLHHPEEPEGKLGPVPSTQQHGEEPGKAV---SSSPDEETG 76
           L +P + +   DPQ +          PEG L P P   Q  E P  ++      P+    
Sbjct: 72  LVSPEVTEPRKDPQGA--------RGPEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLA 123

Query: 77  SPCRL------LRQPEKEPAPLPPSQNSFGRFVPQFAKSRKTVTRKEEM--------KDE 122
           SP          + P +EPAP     N+ G     F   R + T  +E+        + +
Sbjct: 124 SPAAAPEDGPQTQSPRREPAP-----NAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQ 178

Query: 123 DRGSGAFSLETIAESSAQSPGCQ--LLVETLGVPL------------QEATELGDPTQAD 168
            +  G  S  + +    QSPG     L E +  PL            QE    G    A+
Sbjct: 179 PKEEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAE 238

Query: 169 S----ARPEQSSQSPVQAVPGSGDSQ-------------PDDPP------DRGTGLSASQ 205
           S    A  + + ++P  A  G+  S              P DP       +RG G +  Q
Sbjct: 239 SRQGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAPPQ 298

Query: 206 RASQD-------HL--SEQGADDSKPETDRVPGDGGQK---EHLPSIDSEGEKPDRG-AP 252
             + D       HL  S  GA   + E +    +  Q+    +LP  +     P     P
Sbjct: 299 YLTDDLEFLRACHLPRSNSGA-APEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVP 357

Query: 253 QEGGAQRTA--GAGLPGGPQEEGDG-----VPCTPASAPTSGPAPGLGPASWCLEPGSVA 305
           + GG+ + A     + G PQ    G     V C  A     G  P + P    L P   A
Sbjct: 358 EAGGSGKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLP-VSPEPSLLTPTEEA 416

Query: 306 QGSPDPQQTPSR---MGREGEGTHSSLGCSSLGMVVIADLSTDPTE-----LEERALEVA 357
             +      P+    +  E  G+ S    S  GM V AD + +  +     LE +  ++ 
Sbjct: 417 HPASSLASFPAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLG 476

Query: 358 G----PDGQASAISPASPRRKAADGGH------RRALPGCTSLTGETTGESGEAGQDGKP 407
                P+G    +   SP+ +   G H          PG          E     Q G P
Sbjct: 477 SKGEHPEGDPGEVPAPSPQER---GEHLNTEQSHEVQPGVP--PPPLPKEQSHEVQPGAP 531

Query: 408 PGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELGGQNLE 467
           P  +   P+ S    PG  +      DS   +       +    PG  +E  E       
Sbjct: 532 PPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDP 591

Query: 468 RDLEGFRVSPQASVVLEHREIADDPLQEPGAQQGIPDTTSELAGQ 512
            +L+G     QA       E+  D L +P +     D  S  + Q
Sbjct: 592 GNLQG--EDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQ 634



 Score = 34.3 bits (77), Expect = 0.36
 Identities = 108/528 (20%), Positives = 165/528 (31%), Gaps = 115/528 (21%)

Query: 40   LHHPEEPE--------GKLGPVPSTQQHGEEPGKAVSSSPDEETGSPCRL-----LRQPE 86
            +H P EP+        G       ++   + P   +S +P   T SP  +     L +  
Sbjct: 875  IHVPVEPQEDNNLPTHGGQEQALGSELQSQLPKGTLSDTP---TSSPTDMVWESSLTEES 931

Query: 87   KEPAPLPPSQNSFGRFVPQFA-----KSRKTVTRKEEMKDEDRGSGAFSLETIAESSAQS 141
            +  AP      + G   P+ A      SR +    + +KD          ET       +
Sbjct: 932  ELSAPTRQKLPALGEKRPEGACGDGQSSRVSPPAADVLKDFSLAGNFSRKETCCTGQGPN 991

Query: 142  PGCQLLVETL--GVPLQEATEL--GDPTQADSARPEQSSQSPVQAVPGSGDSQPDDPP-- 195
               Q L + L  G   +EA +   G    AD   P         A   +G++ P  P   
Sbjct: 992  KSQQALADALEEGSQHEEACQRHPGASEAADGCSPLWGLSKREMASGNTGEAPPCQPDSV 1051

Query: 196  ---DRGTGLSASQRAS------QDHLSEQGADDSKPETDR-VPGDGGQKEHLPSIDSEGE 245
               D    L A   AS      QD    +  D+++    + VP    + E   + D+E  
Sbjct: 1052 ALLDAVPCLPALAPASPGVTPTQDAPETEACDETQEGRQQPVPAPQQKMECWATSDAESP 1111

Query: 246  KPDRGAPQEGGAQRTAGAGLPGGPQEEGD-GVPCTPASAPTSGPAPGLGPASWCLEPGSV 304
            K     P  G     AGA   GG    GD G    P     +  + GL     CL  G  
Sbjct: 1112 KLLASFPSAGEQGGEAGAAETGGSAGAGDPGKQQAPEKPGEATLSCGLLQTEHCLTSGEE 1171

Query: 305  AQGSPDPQQTPSRMGREGEGTHSSLGCSS-------LGMVVIA--DLSTDPTELEERALE 355
            A        + S +    +  H    C         LG +  +  D ST     + + L 
Sbjct: 1172 A--------STSALRESCQAEHPMASCQDALLPARELGGIPRSTMDFSTHQAVPDPKELL 1223

Query: 356  VAGPDGQASAISP-----ASPRRKAADGGHRRALPGCTSLTGETTGESGEA--------- 401
            ++GP   A+  +P     ++ +R A D G +          GE+    GE          
Sbjct: 1224 LSGPPEVAAPDTPYLHVDSAAQRGAEDSGVKAVSSADPRAPGESPCPVGEPPLALENAAS 1283

Query: 402  -------------------------GQDGKPPGDVLVGPTASL----------------- 419
                                        G P      GP  S+                 
Sbjct: 1284 LKLFAGSLAPLLQPGAAGGEIPAVQASSGSPKARTTEGPVDSMPCLDRMPLLAKGKQATG 1343

Query: 420  ----ALAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELGG 463
                A APG+G    G G +G A+ +T   + +  EP    ++   GG
Sbjct: 1344 EEKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEPSQDPKQGTSGG 1391


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 111/452 (24%), Positives = 145/452 (32%), Gaps = 82/452 (18%)

Query: 43   PEEPEGKLGPVPSTQQHGEEPGKAVSSSPDEETGSPCRLLRQPEKEPAPLPPSQNSFGRF 102
            PE P+G+ GP       G+   K     P    G P    RQ  K     P    + G  
Sbjct: 824  PEGPKGRAGPTGDPGPSGQAGEKGKLGVP----GLPGYPGRQGPKGSTGFPGFPGANGE- 878

Query: 103  VPQFAKSRKTVTRKEEMKDEDRGSGAFSLETIAESSAQSPGCQLLVETLGVPLQEATELG 162
                 K  + V  K   + +   +G           A+ P         G P  + T  G
Sbjct: 879  -----KGARGVAGKPGPRGQRGPTGPRG-----SRGARGP--------TGKPGPKGTSGG 920

Query: 163  D-PTQADSARPEQSSQSPV-----QAVPG--SGDSQPDDPPDRGTGLSASQRASQDHLSE 214
            D P      R  Q  Q PV     +  PG    D  P  P  RG      +         
Sbjct: 921  DGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 980

Query: 215  QGADDSKPETDRV--------PGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLP 266
             G      ET  +        PG  G++    +   EG K D G   +G + +   AGL 
Sbjct: 981  VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP--QGISGKDGPAGLR 1038

Query: 267  GGPQEEG-DGVPCTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGE-G 324
            G P E G  G    P      GP    GP     E GS   G+  P   P R G +G  G
Sbjct: 1039 GFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA--GTAGPIGLPGRPGPQGPPG 1096

Query: 325  THSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQASAIS---PASPRRKAADGGHR 381
                 G                   E+     AG DG    +    PA P     + G +
Sbjct: 1097 PAGEKGAPG----------------EKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1140

Query: 382  RAL--PGCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLALAPGSGE-------SMMG- 431
              +  PG         G  G+ G++G P    L GP  +  +A G GE        M G 
Sbjct: 1141 GEIGEPG-------QKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQ 1193

Query: 432  AGDSG-HASPDTGPCVNQKQEPGPAQEEAELG 462
             GD G    P     +  +  PGP  E+ E G
Sbjct: 1194 KGDEGARGFPGPPGPIGLQGLPGPPGEKGENG 1225



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 76/279 (27%), Positives = 94/279 (33%), Gaps = 59/279 (21%)

Query: 229  GDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQ-EEGDGVPCTPASAP-TS 286
            G  G    + S+   GEK + G     G    AG G P G + E+G+  P   A  P   
Sbjct: 1249 GPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAK 1308

Query: 287  GPAPGLGPASWCLEPGSVA-QGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIADLSTD 345
            GP    GP      PG V   G P P   P   G++G G                    D
Sbjct: 1309 GPPGDDGPKG---NPGPVGFPGDPGPPGEPGPAGQDGVGGDKGE-------------DGD 1352

Query: 346  PTELEERALEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGET--TGESGEAGQ 403
            P +         GP G +    P  P  K       R  PG     G     G  GEAG 
Sbjct: 1353 PGQ--------PGPPGPSGEAGPPGPPGK-------RGPPGAAGAEGRQGEKGAKGEAGA 1397

Query: 404  DGKPPGDVLVGPTA--------SLALAPGS-GESMM--GAGDSGHASPDTGPCV-NQKQE 451
            +G P     VGP           L   PG  GE  +   AG  G   P   P +   K +
Sbjct: 1398 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD 1457

Query: 452  PGPAQEEAELG-----------GQNLERDLEGFRVSPQA 479
            PG   E+   G           G+  +R L G + SP A
Sbjct: 1458 PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGA 1496



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 74/288 (25%), Positives = 102/288 (35%), Gaps = 41/288 (14%)

Query: 151  LGVPLQEATELGDPTQADSARPEQSSQSPVQAVPGSGDSQPDDPPDRGTGLSASQRASQD 210
            +G P  E  E G+     +A P  +   P    P         P D G        A QD
Sbjct: 1283 VGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP-AGQD 1341

Query: 211  HLSEQGADDSKPETDRVPGDGGQ--------KEHLP-SIDSEGEKPDRGAPQEGGAQRTA 261
             +     +D  P     PG  G+        K   P +  +EG + ++GA  E GA+   
Sbjct: 1342 GVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPP 1401

Query: 262  GAGLPGGPQEEGDGVPCTPASAPTSGPAPGL-GPASWCLEPGSVAQ-GSPDPQQTPSRMG 319
            G   P GPQ         PA  P      G+ GP      PG+  Q G P P   P   G
Sbjct: 1402 GKTGPVGPQ--------GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPG 1453

Query: 320  REGE-GTHSSLGCSSLGMVVIADLSTDPTELEERALE----VAGPDGQASAISPASPRRK 374
             +G+ G+    G    G++ +     +  E  +R L       G  G      PA P   
Sbjct: 1454 LKGDPGSKGEKG--HPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP 1511

Query: 375  AADGGHRRALPGCTSLTGE--TTGESGEAGQDG--------KPPGDVL 412
                G    LPG     G   +TG +G+ G  G         PPG+V+
Sbjct: 1512 PGPPG----LPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVI 1555



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 91/346 (26%), Positives = 109/346 (31%), Gaps = 67/346 (19%)

Query: 154  PLQEATELGDPTQADSARP--EQSSQSPVQAVPGSGD--SQPDDPPDRGTGLSASQRASQ 209
            P   A E G P +     P      Q PV  +PG       P +  D+G      Q+ S+
Sbjct: 1094 PPGPAGEKGAPGEKGPQGPAGRDGVQGPV-GLPGPAGPAGSPGEDGDKGEIGEPGQKGSK 1152

Query: 210  DHLSEQGADDSK-----------PETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQ 258
                E G                   D  PG  GQ+        EG +   G P   G Q
Sbjct: 1153 GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ 1212

Query: 259  RTAGAGLPGGPQEEGDGVPCTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRM 318
                 GLPG P E+G+     P   P  GP    GP            G+  PQ  P  +
Sbjct: 1213 -----GLPGPPGEKGENGDVGPMGPP--GPPGPRGPQG--------PNGADGPQGPPGSV 1257

Query: 319  GREGEGTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADG 378
            G  G       G    G    A     P E       V GP G+      A P   A   
Sbjct: 1258 GSVG-------GVGEKGEPGEAGNPGPPGE-----AGVGGPKGERGEKGEAGPPGAAGPP 1305

Query: 379  GHR--------RALPGCTSLTGE--TTGESGEAGQDGKPPGDVLVGPTASLALAPGSGES 428
            G +        +  PG     G+    GE G AGQDG       VG        PG    
Sbjct: 1306 GAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDG-------VGGDKGEDGDPGQPGP 1358

Query: 429  MMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELG--GQNLERDLEG 472
                G SG A P   P   ++  PG A  E   G  G   E   EG
Sbjct: 1359 ---PGPSGEAGPPGPP--GKRGPPGAAGAEGRQGEKGAKGEAGAEG 1399



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 102/415 (24%), Positives = 129/415 (31%), Gaps = 92/415 (22%)

Query: 86  EKEPAPLPPSQNSFGRFVPQFAKSRKTVTRKEEMKDEDRGSGAFSLE-TIAESSAQSPGC 144
           E E  P  P    FG  VP      +T            G GA+  +    E +   PG 
Sbjct: 400 EYEDKPTSPPNEEFGPGVPAETDITETSIN---------GHGAYGEKGQKGEPAVVEPG- 449

Query: 145 QLLVETLGVPLQEATELGDP-TQADSARPEQSSQSPVQAVPG--SGDSQPDDPP------ 195
            +LVE    P   A  +G P  Q  +  P           PG    D  P  P       
Sbjct: 450 -MLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLP 508

Query: 196 -------DRGTGLSASQRASQDHLSE-----QGADDSKPETDRV-----PGDGGQKEHLP 238
                   +G  +SA +  +Q  L +     +G       T R      PG  G K    
Sbjct: 509 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 568

Query: 239 SIDSEGEKPDRGAP-------QEGGAQRTAGAGLPGGPQEEGD----GVPCTPASAPTSG 287
               +G +  +G P       + G      G G+PG P  +GD    G+P  P      G
Sbjct: 569 DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRG 628

Query: 288 PAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIADLSTDPT 347
                GP           QG P P       G +GE     +G   L           P 
Sbjct: 629 ER---GP-----------QGPPGPPGDDGMRGEDGE-----IGPRGL-----------PG 658

Query: 348 ELEERALEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGETTGESGEAGQDGKP 407
           E   R L   GP G   A  P  P     DG      PG     G   GE G  GQ G P
Sbjct: 659 EAGPRGL--LGPRGTPGA--PGQPGMAGVDGP-----PGPKGNMGPQ-GEPGPPGQQGNP 708

Query: 408 PGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELG 462
               L GP   +   PG        G +G    D  P      + G + E+  LG
Sbjct: 709 GPQGLPGPQGPIG-PPGEKGPQGKPGLAGLPGADGPP--GHPGKEGQSGEKGALG 760


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 111/452 (24%), Positives = 145/452 (32%), Gaps = 82/452 (18%)

Query: 43   PEEPEGKLGPVPSTQQHGEEPGKAVSSSPDEETGSPCRLLRQPEKEPAPLPPSQNSFGRF 102
            PE P+G+ GP       G+   K     P    G P    RQ  K     P    + G  
Sbjct: 773  PEGPKGRAGPTGDPGPSGQAGEKGKLGVP----GLPGYPGRQGPKGSTGFPGFPGANGE- 827

Query: 103  VPQFAKSRKTVTRKEEMKDEDRGSGAFSLETIAESSAQSPGCQLLVETLGVPLQEATELG 162
                 K  + V  K   + +   +G           A+ P         G P  + T  G
Sbjct: 828  -----KGARGVAGKPGPRGQRGPTGPRG-----SRGARGP--------TGKPGPKGTSGG 869

Query: 163  D-PTQADSARPEQSSQSPV-----QAVPG--SGDSQPDDPPDRGTGLSASQRASQDHLSE 214
            D P      R  Q  Q PV     +  PG    D  P  P  RG      +         
Sbjct: 870  DGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 929

Query: 215  QGADDSKPETDRV--------PGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLP 266
             G      ET  +        PG  G++    +   EG K D G   +G + +   AGL 
Sbjct: 930  VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP--QGISGKDGPAGLR 987

Query: 267  GGPQEEG-DGVPCTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGE-G 324
            G P E G  G    P      GP    GP     E GS   G+  P   P R G +G  G
Sbjct: 988  GFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA--GTAGPIGLPGRPGPQGPPG 1045

Query: 325  THSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQASAIS---PASPRRKAADGGHR 381
                 G                   E+     AG DG    +    PA P     + G +
Sbjct: 1046 PAGEKGAPG----------------EKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1089

Query: 382  RAL--PGCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLALAPGSGE-------SMMG- 431
              +  PG         G  G+ G++G P    L GP  +  +A G GE        M G 
Sbjct: 1090 GEIGEPG-------QKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQ 1142

Query: 432  AGDSG-HASPDTGPCVNQKQEPGPAQEEAELG 462
             GD G    P     +  +  PGP  E+ E G
Sbjct: 1143 KGDEGARGFPGPPGPIGLQGLPGPPGEKGENG 1174



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 76/279 (27%), Positives = 94/279 (33%), Gaps = 59/279 (21%)

Query: 229  GDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQ-EEGDGVPCTPASAP-TS 286
            G  G    + S+   GEK + G     G    AG G P G + E+G+  P   A  P   
Sbjct: 1198 GPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAK 1257

Query: 287  GPAPGLGPASWCLEPGSVA-QGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIADLSTD 345
            GP    GP      PG V   G P P   P   G++G G                    D
Sbjct: 1258 GPPGDDGPKG---NPGPVGFPGDPGPPGEPGPAGQDGVGGDKGE-------------DGD 1301

Query: 346  PTELEERALEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGET--TGESGEAGQ 403
            P +         GP G +    P  P  K       R  PG     G     G  GEAG 
Sbjct: 1302 PGQ--------PGPPGPSGEAGPPGPPGK-------RGPPGAAGAEGRQGEKGAKGEAGA 1346

Query: 404  DGKPPGDVLVGPTA--------SLALAPGS-GESMM--GAGDSGHASPDTGPCV-NQKQE 451
            +G P     VGP           L   PG  GE  +   AG  G   P   P +   K +
Sbjct: 1347 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD 1406

Query: 452  PGPAQEEAELG-----------GQNLERDLEGFRVSPQA 479
            PG   E+   G           G+  +R L G + SP A
Sbjct: 1407 PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGA 1445



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 74/288 (25%), Positives = 102/288 (35%), Gaps = 41/288 (14%)

Query: 151  LGVPLQEATELGDPTQADSARPEQSSQSPVQAVPGSGDSQPDDPPDRGTGLSASQRASQD 210
            +G P  E  E G+     +A P  +   P    P         P D G        A QD
Sbjct: 1232 VGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP-AGQD 1290

Query: 211  HLSEQGADDSKPETDRVPGDGGQ--------KEHLP-SIDSEGEKPDRGAPQEGGAQRTA 261
             +     +D  P     PG  G+        K   P +  +EG + ++GA  E GA+   
Sbjct: 1291 GVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPP 1350

Query: 262  GAGLPGGPQEEGDGVPCTPASAPTSGPAPGL-GPASWCLEPGSVAQ-GSPDPQQTPSRMG 319
            G   P GPQ         PA  P      G+ GP      PG+  Q G P P   P   G
Sbjct: 1351 GKTGPVGPQ--------GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPG 1402

Query: 320  REGE-GTHSSLGCSSLGMVVIADLSTDPTELEERALE----VAGPDGQASAISPASPRRK 374
             +G+ G+    G    G++ +     +  E  +R L       G  G      PA P   
Sbjct: 1403 LKGDPGSKGEKG--HPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP 1460

Query: 375  AADGGHRRALPGCTSLTGE--TTGESGEAGQDG--------KPPGDVL 412
                G    LPG     G   +TG +G+ G  G         PPG+V+
Sbjct: 1461 PGPPG----LPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVI 1504



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 91/346 (26%), Positives = 109/346 (31%), Gaps = 67/346 (19%)

Query: 154  PLQEATELGDPTQADSARP--EQSSQSPVQAVPGSGD--SQPDDPPDRGTGLSASQRASQ 209
            P   A E G P +     P      Q PV  +PG       P +  D+G      Q+ S+
Sbjct: 1043 PPGPAGEKGAPGEKGPQGPAGRDGVQGPV-GLPGPAGPAGSPGEDGDKGEIGEPGQKGSK 1101

Query: 210  DHLSEQGADDSK-----------PETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQ 258
                E G                   D  PG  GQ+        EG +   G P   G Q
Sbjct: 1102 GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ 1161

Query: 259  RTAGAGLPGGPQEEGDGVPCTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRM 318
                 GLPG P E+G+     P   P  GP    GP            G+  PQ  P  +
Sbjct: 1162 -----GLPGPPGEKGENGDVGPMGPP--GPPGPRGPQG--------PNGADGPQGPPGSV 1206

Query: 319  GREGEGTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADG 378
            G  G       G    G    A     P E       V GP G+      A P   A   
Sbjct: 1207 GSVG-------GVGEKGEPGEAGNPGPPGE-----AGVGGPKGERGEKGEAGPPGAAGPP 1254

Query: 379  GHR--------RALPGCTSLTGE--TTGESGEAGQDGKPPGDVLVGPTASLALAPGSGES 428
            G +        +  PG     G+    GE G AGQDG       VG        PG    
Sbjct: 1255 GAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDG-------VGGDKGEDGDPGQPGP 1307

Query: 429  MMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELG--GQNLERDLEG 472
                G SG A P   P   ++  PG A  E   G  G   E   EG
Sbjct: 1308 ---PGPSGEAGPPGPP--GKRGPPGAAGAEGRQGEKGAKGEAGAEG 1348



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 102/415 (24%), Positives = 129/415 (31%), Gaps = 92/415 (22%)

Query: 86  EKEPAPLPPSQNSFGRFVPQFAKSRKTVTRKEEMKDEDRGSGAFSLE-TIAESSAQSPGC 144
           E E  P  P    FG  VP      +T            G GA+  +    E +   PG 
Sbjct: 349 EYEDKPTSPPNEEFGPGVPAETDITETSIN---------GHGAYGEKGQKGEPAVVEPG- 398

Query: 145 QLLVETLGVPLQEATELGDP-TQADSARPEQSSQSPVQAVPG--SGDSQPDDPP------ 195
            +LVE    P   A  +G P  Q  +  P           PG    D  P  P       
Sbjct: 399 -MLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLP 457

Query: 196 -------DRGTGLSASQRASQDHLSE-----QGADDSKPETDRV-----PGDGGQKEHLP 238
                   +G  +SA +  +Q  L +     +G       T R      PG  G K    
Sbjct: 458 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 517

Query: 239 SIDSEGEKPDRGAP-------QEGGAQRTAGAGLPGGPQEEGD----GVPCTPASAPTSG 287
               +G +  +G P       + G      G G+PG P  +GD    G+P  P      G
Sbjct: 518 DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRG 577

Query: 288 PAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIADLSTDPT 347
                GP           QG P P       G +GE     +G   L           P 
Sbjct: 578 ER---GP-----------QGPPGPPGDDGMRGEDGE-----IGPRGL-----------PG 607

Query: 348 ELEERALEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGETTGESGEAGQDGKP 407
           E   R L   GP G   A  P  P     DG      PG     G   GE G  GQ G P
Sbjct: 608 EAGPRGL--LGPRGTPGA--PGQPGMAGVDGP-----PGPKGNMGPQ-GEPGPPGQQGNP 657

Query: 408 PGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELG 462
               L GP   +   PG        G +G    D  P      + G + E+  LG
Sbjct: 658 GPQGLPGPQGPIG-PPGEKGPQGKPGLAGLPGADGPP--GHPGKEGQSGEKGALG 709


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 111/452 (24%), Positives = 145/452 (32%), Gaps = 82/452 (18%)

Query: 43   PEEPEGKLGPVPSTQQHGEEPGKAVSSSPDEETGSPCRLLRQPEKEPAPLPPSQNSFGRF 102
            PE P+G+ GP       G+   K     P    G P    RQ  K     P    + G  
Sbjct: 812  PEGPKGRAGPTGDPGPSGQAGEKGKLGVP----GLPGYPGRQGPKGSTGFPGFPGANGE- 866

Query: 103  VPQFAKSRKTVTRKEEMKDEDRGSGAFSLETIAESSAQSPGCQLLVETLGVPLQEATELG 162
                 K  + V  K   + +   +G           A+ P         G P  + T  G
Sbjct: 867  -----KGARGVAGKPGPRGQRGPTGPRG-----SRGARGP--------TGKPGPKGTSGG 908

Query: 163  D-PTQADSARPEQSSQSPV-----QAVPG--SGDSQPDDPPDRGTGLSASQRASQDHLSE 214
            D P      R  Q  Q PV     +  PG    D  P  P  RG      +         
Sbjct: 909  DGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 968

Query: 215  QGADDSKPETDRV--------PGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLP 266
             G      ET  +        PG  G++    +   EG K D G   +G + +   AGL 
Sbjct: 969  VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP--QGISGKDGPAGLR 1026

Query: 267  GGPQEEG-DGVPCTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGE-G 324
            G P E G  G    P      GP    GP     E GS   G+  P   P R G +G  G
Sbjct: 1027 GFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA--GTAGPIGLPGRPGPQGPPG 1084

Query: 325  THSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQASAIS---PASPRRKAADGGHR 381
                 G                   E+     AG DG    +    PA P     + G +
Sbjct: 1085 PAGEKGAPG----------------EKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1128

Query: 382  RAL--PGCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLALAPGSGE-------SMMG- 431
              +  PG         G  G+ G++G P    L GP  +  +A G GE        M G 
Sbjct: 1129 GEIGEPG-------QKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQ 1181

Query: 432  AGDSG-HASPDTGPCVNQKQEPGPAQEEAELG 462
             GD G    P     +  +  PGP  E+ E G
Sbjct: 1182 KGDEGARGFPGPPGPIGLQGLPGPPGEKGENG 1213



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 76/279 (27%), Positives = 94/279 (33%), Gaps = 59/279 (21%)

Query: 229  GDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQ-EEGDGVPCTPASAP-TS 286
            G  G    + S+   GEK + G     G    AG G P G + E+G+  P   A  P   
Sbjct: 1237 GPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAK 1296

Query: 287  GPAPGLGPASWCLEPGSVA-QGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIADLSTD 345
            GP    GP      PG V   G P P   P   G++G G                    D
Sbjct: 1297 GPPGDDGPKG---NPGPVGFPGDPGPPGEPGPAGQDGVGGDKGE-------------DGD 1340

Query: 346  PTELEERALEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGET--TGESGEAGQ 403
            P +         GP G +    P  P  K       R  PG     G     G  GEAG 
Sbjct: 1341 PGQ--------PGPPGPSGEAGPPGPPGK-------RGPPGAAGAEGRQGEKGAKGEAGA 1385

Query: 404  DGKPPGDVLVGPTA--------SLALAPGS-GESMM--GAGDSGHASPDTGPCV-NQKQE 451
            +G P     VGP           L   PG  GE  +   AG  G   P   P +   K +
Sbjct: 1386 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD 1445

Query: 452  PGPAQEEAELG-----------GQNLERDLEGFRVSPQA 479
            PG   E+   G           G+  +R L G + SP A
Sbjct: 1446 PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGA 1484



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 74/288 (25%), Positives = 102/288 (35%), Gaps = 41/288 (14%)

Query: 151  LGVPLQEATELGDPTQADSARPEQSSQSPVQAVPGSGDSQPDDPPDRGTGLSASQRASQD 210
            +G P  E  E G+     +A P  +   P    P         P D G        A QD
Sbjct: 1271 VGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP-AGQD 1329

Query: 211  HLSEQGADDSKPETDRVPGDGGQ--------KEHLP-SIDSEGEKPDRGAPQEGGAQRTA 261
             +     +D  P     PG  G+        K   P +  +EG + ++GA  E GA+   
Sbjct: 1330 GVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPP 1389

Query: 262  GAGLPGGPQEEGDGVPCTPASAPTSGPAPGL-GPASWCLEPGSVAQ-GSPDPQQTPSRMG 319
            G   P GPQ         PA  P      G+ GP      PG+  Q G P P   P   G
Sbjct: 1390 GKTGPVGPQ--------GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPG 1441

Query: 320  REGE-GTHSSLGCSSLGMVVIADLSTDPTELEERALE----VAGPDGQASAISPASPRRK 374
             +G+ G+    G    G++ +     +  E  +R L       G  G      PA P   
Sbjct: 1442 LKGDPGSKGEKG--HPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP 1499

Query: 375  AADGGHRRALPGCTSLTGE--TTGESGEAGQDG--------KPPGDVL 412
                G    LPG     G   +TG +G+ G  G         PPG+V+
Sbjct: 1500 PGPPG----LPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVI 1543



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 91/346 (26%), Positives = 109/346 (31%), Gaps = 67/346 (19%)

Query: 154  PLQEATELGDPTQADSARP--EQSSQSPVQAVPGSGD--SQPDDPPDRGTGLSASQRASQ 209
            P   A E G P +     P      Q PV  +PG       P +  D+G      Q+ S+
Sbjct: 1082 PPGPAGEKGAPGEKGPQGPAGRDGVQGPV-GLPGPAGPAGSPGEDGDKGEIGEPGQKGSK 1140

Query: 210  DHLSEQGADDSK-----------PETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQ 258
                E G                   D  PG  GQ+        EG +   G P   G Q
Sbjct: 1141 GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ 1200

Query: 259  RTAGAGLPGGPQEEGDGVPCTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRM 318
                 GLPG P E+G+     P   P  GP    GP            G+  PQ  P  +
Sbjct: 1201 -----GLPGPPGEKGENGDVGPMGPP--GPPGPRGPQG--------PNGADGPQGPPGSV 1245

Query: 319  GREGEGTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADG 378
            G  G       G    G    A     P E       V GP G+      A P   A   
Sbjct: 1246 GSVG-------GVGEKGEPGEAGNPGPPGE-----AGVGGPKGERGEKGEAGPPGAAGPP 1293

Query: 379  GHR--------RALPGCTSLTGE--TTGESGEAGQDGKPPGDVLVGPTASLALAPGSGES 428
            G +        +  PG     G+    GE G AGQDG       VG        PG    
Sbjct: 1294 GAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDG-------VGGDKGEDGDPGQPGP 1346

Query: 429  MMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELG--GQNLERDLEG 472
                G SG A P   P   ++  PG A  E   G  G   E   EG
Sbjct: 1347 ---PGPSGEAGPPGPP--GKRGPPGAAGAEGRQGEKGAKGEAGAEG 1387



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 102/415 (24%), Positives = 129/415 (31%), Gaps = 92/415 (22%)

Query: 86  EKEPAPLPPSQNSFGRFVPQFAKSRKTVTRKEEMKDEDRGSGAFSLE-TIAESSAQSPGC 144
           E E  P  P    FG  VP      +T            G GA+  +    E +   PG 
Sbjct: 388 EYEDKPTSPPNEEFGPGVPAETDITETSIN---------GHGAYGEKGQKGEPAVVEPG- 437

Query: 145 QLLVETLGVPLQEATELGDP-TQADSARPEQSSQSPVQAVPG--SGDSQPDDPP------ 195
            +LVE    P   A  +G P  Q  +  P           PG    D  P  P       
Sbjct: 438 -MLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLP 496

Query: 196 -------DRGTGLSASQRASQDHLSE-----QGADDSKPETDRV-----PGDGGQKEHLP 238
                   +G  +SA +  +Q  L +     +G       T R      PG  G K    
Sbjct: 497 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 556

Query: 239 SIDSEGEKPDRGAP-------QEGGAQRTAGAGLPGGPQEEGD----GVPCTPASAPTSG 287
               +G +  +G P       + G      G G+PG P  +GD    G+P  P      G
Sbjct: 557 DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRG 616

Query: 288 PAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIADLSTDPT 347
                GP           QG P P       G +GE     +G   L           P 
Sbjct: 617 ER---GP-----------QGPPGPPGDDGMRGEDGE-----IGPRGL-----------PG 646

Query: 348 ELEERALEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGETTGESGEAGQDGKP 407
           E   R L   GP G   A  P  P     DG      PG     G   GE G  GQ G P
Sbjct: 647 EAGPRGL--LGPRGTPGA--PGQPGMAGVDGP-----PGPKGNMGPQ-GEPGPPGQQGNP 696

Query: 408 PGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELG 462
               L GP   +   PG        G +G    D  P      + G + E+  LG
Sbjct: 697 GPQGLPGPQGPIG-PPGEKGPQGKPGLAGLPGADGPP--GHPGKEGQSGEKGALG 748


>gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens]
          Length = 540

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 75/284 (26%), Positives = 103/284 (36%), Gaps = 46/284 (16%)

Query: 229 GDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQ----EEGD---------- 274
           GD GQ          G    RG P + G     GA  P GP+    ++G+          
Sbjct: 175 GDQGQDGAAGPPGPPGPPGARGPPGDTGKDGPRGAQGPAGPKGEPGQDGEMGPKGPPGPK 234

Query: 275 GVPCTPASAPTSGPAPGLGPASWCLEPGSV-------AQGSPDPQQTPSRMGREG-EGTH 326
           G P  P      G     GP     EPGS+         G+P P+  P   G +G  G  
Sbjct: 235 GEPGVPGKKGDDGTPSQPGPPGPKGEPGSMGPRGENGVDGAPGPKGEPGHRGTDGAAGPR 294

Query: 327 SSLGC-SSLGMVVIADLSTDPTELEERALE-VAGPDGQASAISPASPRRKAADGGHRRAL 384
            + G     G  V+ D        + R L+ + GP G      P  P    A G     L
Sbjct: 295 GAPGLKGEQGDTVVID-------YDGRILDALKGPPGPQG--PPGPPGIPGAKG--ELGL 343

Query: 385 PGCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLALA--PGS----GESMMGAGDSGHA 438
           PG   + GE  G  G+ G  G+P    L G    + L+  PG+    GE    A DS   
Sbjct: 344 PGAPGIDGE-KGPKGQKGDPGEPGPAGLKGEAGEMGLSGLPGADGLKGEKGESASDSLQE 402

Query: 439 SPDTGPCVNQKQEPGPAQEEAELGGQNLE--RDLEGFRVSPQAS 480
           S      + +   PGP      +G Q ++  + L+G +    AS
Sbjct: 403 S--LAQLIVEPGPPGPPGPPGPMGLQGIQGPKGLDGAKGEKGAS 444



 Score = 38.9 bits (89), Expect = 0.015
 Identities = 90/363 (24%), Positives = 118/363 (32%), Gaps = 57/363 (15%)

Query: 165 TQADSARPEQSSQSPVQAVPGSGDSQPDDPPDRGTGLSASQRASQDHLSEQGADDSKPET 224
           T  D  R  Q    P       G+  P  PP             +  +  +  DD  P  
Sbjct: 201 TGKDGPRGAQGPAGPKGEPGQDGEMGPKGPPGP---------KGEPGVPGKKGDDGTPSQ 251

Query: 225 DRVPGDGGQKEHLPSIDSEGEKPDRGAP---QEGGAQRTAGA----GLPGGPQEEGDGV- 276
              PG  G K    S+   GE    GAP    E G + T GA    G PG   E+GD V 
Sbjct: 252 ---PGPPGPKGEPGSMGPRGENGVDGAPGPKGEPGHRGTDGAAGPRGAPGLKGEQGDTVV 308

Query: 277 -------------PCTPASAPTSGPAPGL-GPASWCLEPGSVAQGSPDPQQ-TPSRMGRE 321
                        P  P   P     PG  G       PG   +  P  Q+  P   G  
Sbjct: 309 IDYDGRILDALKGPPGPQGPPGPPGIPGAKGELGLPGAPGIDGEKGPKGQKGDPGEPGPA 368

Query: 322 G-EGTHSSLGCSSL----GMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAA 376
           G +G    +G S L    G+      S   + L+E   ++    G      P  P     
Sbjct: 369 GLKGEAGEMGLSGLPGADGLKGEKGESASDS-LQESLAQLIVEPGPPGPPGPPGPMGLQG 427

Query: 377 DGGHRRALPGCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGAGDSG 436
             G +    G     GE  G SGE G  G P     VGP   + L    GE     G  G
Sbjct: 428 IQGPK----GLDGAKGE-KGASGERGPSGLPGP---VGPPGLIGLPGTKGEK----GRPG 475

Query: 437 HASPDTGPCVNQKQEPGPAQEEAELGGQNL--ERDLEGFRVSPQASVVLEHREIADDPLQ 494
               D  P    + E G   E  E G + +   + ++G +  P    + +   +  D L 
Sbjct: 476 EPGLDGFP--GPRGEKGDRSERGEKGERGVPGRKGVKGQKGEPGPPGLDQPCPVGPDGLP 533

Query: 495 EPG 497
            PG
Sbjct: 534 VPG 536


>gi|50511941 EMI domain containing 1 [Homo sapiens]
          Length = 443

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 76/282 (26%), Positives = 102/282 (36%), Gaps = 50/282 (17%)

Query: 244 GEKPDRGAPQEGGAQRTAGA-GLPGGPQEEGDGVPCTPASAPTSGPAPGLGPASWCLEPG 302
           G  P +G+P +GG Q   GA GLPG    +GD        A + GP    GP      PG
Sbjct: 181 GPPPAQGSPGDGGLQDQVGAWGLPGPTGPKGD--------AGSRGPMGMRGPPGPQGPPG 232

Query: 303 SV----AQGSPDPQQTPSRMGREG-EGTHSSLGCSSLGMVVIAD--LSTDPTELEERALE 355
           S     A G+P  +  P   G  G  G  + +G     +    D  LS   TE      +
Sbjct: 233 SPGRAGAVGTPGERGPPGPPGPPGPPGPPAPVGPPHARISQHGDPLLSNTFTETNNHWPQ 292

Query: 356 -VAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGETTGESGEAGQDGKPPGDVLVG 414
              GP G    + P  P             PG        TG  G  G  G P      G
Sbjct: 293 GPTGPPGPPGPMGPPGP-------------PG-------PTGVPGSPGHIGPP------G 326

Query: 415 PTASLALAPGSGESMMGAGDSG-HASPDTGPCVNQKQEPGPAQEEAELG--GQNLERDLE 471
           PT    ++   GE     G+ G    P       Q+ EPGP  +  E    G+ L +  E
Sbjct: 327 PTGPKGISGHPGEK----GERGLRGEPGPQGSAGQRGEPGPKGDPGEKSHWGEGLHQLRE 382

Query: 472 GFRVSPQASVVLEHREIADDPLQEPGAQQGIPDTTSELAGQR 513
             ++  +  ++LE      +P    GA      T S L G+R
Sbjct: 383 ALKILAERVLILETMIGLYEPELGSGAGPAGTGTPSLLRGKR 424



 Score = 37.4 bits (85), Expect = 0.043
 Identities = 53/214 (24%), Positives = 66/214 (30%), Gaps = 14/214 (6%)

Query: 177 QSPVQAVPGSGDSQPDDPPDRGTGLSASQRASQDHLSEQGADDSKPETDRVPGDGGQKEH 236
           + PV   P +    P+DP        A        L +Q      P      GD G +  
Sbjct: 163 EQPVPPTPAT----PEDPAPLWGPPPAQGSPGDGGLQDQVGAWGLPGPTGPKGDAGSRGP 218

Query: 237 LPSIDSEGEKPDRGAPQEGGAQRTAG----AGLPGGPQEEGDGVPCTPASAPTSGPAPGL 292
           +      G +   G+P   GA  T G     G PG P   G   P  P  A  S     L
Sbjct: 219 MGMRGPPGPQGPPGSPGRAGAVGTPGERGPPGPPGPPGPPGPPAPVGPPHARISQHGDPL 278

Query: 293 GPASWCLEPGSVAQGSPDPQQTPSRMGREG----EGTHSSLG-CSSLGMVVIADLSTDPT 347
              ++        QG   P   P  MG  G     G   S G     G      +S  P 
Sbjct: 279 LSNTFTETNNHWPQGPTGPPGPPGPMGPPGPPGPTGVPGSPGHIGPPGPTGPKGISGHPG 338

Query: 348 ELEERALE-VAGPDGQASAISPASPRRKAADGGH 380
           E  ER L    GP G A       P+    +  H
Sbjct: 339 EKGERGLRGEPGPQGSAGQRGEPGPKGDPGEKSH 372


>gi|194294532 alpha 1 type XIII collagen isoform 20 [Homo sapiens]
          Length = 717

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 97/365 (26%), Positives = 127/365 (34%), Gaps = 73/365 (20%)

Query: 227 VPGDGGQK-----EHLPSI-DSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTP 280
           +PG  G+K       LP +   +GEK D G    GG       GLPG P  +G+      
Sbjct: 348 IPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGE------ 401

Query: 281 ASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIA 340
                +G    +GP     +PG   +     +Q P       +G   S G    G +V  
Sbjct: 402 -----AGVDGQVGPPG---QPGDKGERGAAGEQGP-------DGPKGSKGEPGKGEMVDY 446

Query: 341 DLSTDPTELEERALEVAGPDGQASAI----SPASPRRKAADGGHRRALPGCTSLTGETTG 396
           + + +    E R L + GP G    I    +P  P +K   G     LPG         G
Sbjct: 447 NGNINEALQEIRTLALMGPPGLPGQIGPPGAPGIPGQKGEIG-----LPG-------PPG 494

Query: 397 ESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQ 456
             GE G  GK PGD  +GP       PG        G++GH              PG   
Sbjct: 495 HDGEKGPRGK-PGD--MGPPGPQG-PPGKDGPPGVKGENGHPG-----------SPGEKG 539

Query: 457 EEAELG--GQNLERDLEGFRVSPQASVVLEHREIADDPLQEPGAQQGIPDTTSELAGQRD 514
           E+ E G  G   E+   G + +P A V        + P   PG  QG+P    E AG   
Sbjct: 540 EKGETGQAGSPGEKGEAGEKGNPGAEV--PGLPGPEGPPGPPGL-QGVPGPKGE-AGLDG 595

Query: 515 HLPHSADQGTWADSLAVELDFLLDSQIQDALDASDFEAPPEQLFPSGNKPGPCWPGPSSH 574
                  QG   D   + L          A        PP    P G  PGP  P     
Sbjct: 596 AKGEKGFQGEKGDRGPLGL--------PGASGLDGRPGPPGTPGPIG-VPGPAGPKGERG 646

Query: 575 ANGDP 579
           + GDP
Sbjct: 647 SKGDP 651



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 58/194 (29%), Positives = 69/194 (35%), Gaps = 44/194 (22%)

Query: 222 PETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPA 281
           P  D  PG  G+  H  S   +GEK + G  Q G       AG  G P  E  G+P    
Sbjct: 517 PGKDGPPGVKGENGHPGSPGEKGEKGETG--QAGSPGEKGEAGEKGNPGAEVPGLP---- 570

Query: 282 SAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGE-GTHSSLG-CSSLGMVVI 339
             P   P P          PG   QG P P+      G +GE G     G    LG+   
Sbjct: 571 -GPEGPPGP----------PG--LQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGA 617

Query: 340 ADLSTDPTELEERALEVAGPDGQASAI---SPASPRRKAADGGHRRALPGCTSLTGETTG 396
           + L   P           GP G    I    PA P+ +    G     PG T      TG
Sbjct: 618 SGLDGRP-----------GPPGTPGPIGVPGPAGPKGERGSKGD----PGMTG----PTG 658

Query: 397 ESGEAGQDGKPPGD 410
            +G  G  G PPGD
Sbjct: 659 AAGLPGLHG-PPGD 671


>gi|22027607 alpha 1 type XIII collagen isoform 18 [Homo sapiens]
          Length = 655

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 97/365 (26%), Positives = 127/365 (34%), Gaps = 73/365 (20%)

Query: 227 VPGDGGQK-----EHLPSI-DSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTP 280
           +PG  G+K       LP +   +GEK D G    GG       GLPG P  +G+      
Sbjct: 286 IPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGE------ 339

Query: 281 ASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIA 340
                +G    +GP     +PG   +     +Q P       +G   S G    G +V  
Sbjct: 340 -----AGVDGQVGPPG---QPGDKGERGAAGEQGP-------DGPKGSKGEPGKGEMVDY 384

Query: 341 DLSTDPTELEERALEVAGPDGQASAI----SPASPRRKAADGGHRRALPGCTSLTGETTG 396
           + + +    E R L + GP G    I    +P  P +K   G     LPG         G
Sbjct: 385 NGNINEALQEIRTLALMGPPGLPGQIGPPGAPGIPGQKGEIG-----LPG-------PPG 432

Query: 397 ESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQ 456
             GE G  GK PGD  +GP       PG        G++GH              PG   
Sbjct: 433 HDGEKGPRGK-PGD--MGPPGPQG-PPGKDGPPGVKGENGHPG-----------SPGEKG 477

Query: 457 EEAELG--GQNLERDLEGFRVSPQASVVLEHREIADDPLQEPGAQQGIPDTTSELAGQRD 514
           E+ E G  G   E+   G + +P A V        + P   PG  QG+P    E AG   
Sbjct: 478 EKGETGQAGSPGEKGEAGEKGNPGAEV--PGLPGPEGPPGPPGL-QGVPGPKGE-AGLDG 533

Query: 515 HLPHSADQGTWADSLAVELDFLLDSQIQDALDASDFEAPPEQLFPSGNKPGPCWPGPSSH 574
                  QG   D   + L          A        PP    P G  PGP  P     
Sbjct: 534 AKGEKGFQGEKGDRGPLGL--------PGASGLDGRPGPPGTPGPIG-VPGPAGPKGERG 584

Query: 575 ANGDP 579
           + GDP
Sbjct: 585 SKGDP 589



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 68/235 (28%), Positives = 81/235 (34%), Gaps = 40/235 (17%)

Query: 228 PGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPASAPTSG 287
           PG  GQK         GE P RG   +   Q     G PG P   G   P      P   
Sbjct: 180 PGPQGQKGEKGQC---GEYPHRGEQSQASIQ-----GPPGPPGPPGPSGPLGHPGLPGPM 231

Query: 288 PAPGL-GPASWCLEPGSVAQGSPDPQQTPSRMGREG----EGTHSSLGCSSLGMVVIADL 342
             PGL GP      PG   +G P  Q    R G  G     G H + G   + +  +   
Sbjct: 232 GPPGLPGP------PG--PKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGE 283

Query: 343 STDPTELEERALEVAGPDGQASAISPASPRRKAADG-GHRRALPGCTSLTGETTGESGEA 401
              P    E+  E  G  G    +     +  A +  G  R  PG   L G   G  GEA
Sbjct: 284 PGIPGTKGEKGAE--GSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPG-PPGPKGEA 340

Query: 402 GQDGKPPGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQ 456
           G DG+      VGP       PG        G +G   PD GP    K EPG  +
Sbjct: 341 GVDGQ------VGP-------PGQPGDKGERGAAGEQGPD-GP-KGSKGEPGKGE 380



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 58/194 (29%), Positives = 69/194 (35%), Gaps = 44/194 (22%)

Query: 222 PETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPA 281
           P  D  PG  G+  H  S   +GEK + G  Q G       AG  G P  E  G+P    
Sbjct: 455 PGKDGPPGVKGENGHPGSPGEKGEKGETG--QAGSPGEKGEAGEKGNPGAEVPGLP---- 508

Query: 282 SAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGE-GTHSSLG-CSSLGMVVI 339
             P   P P          PG   QG P P+      G +GE G     G    LG+   
Sbjct: 509 -GPEGPPGP----------PG--LQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGA 555

Query: 340 ADLSTDPTELEERALEVAGPDGQASAI---SPASPRRKAADGGHRRALPGCTSLTGETTG 396
           + L   P           GP G    I    PA P+ +    G     PG T      TG
Sbjct: 556 SGLDGRP-----------GPPGTPGPIGVPGPAGPKGERGSKGD----PGMTG----PTG 596

Query: 397 ESGEAGQDGKPPGD 410
            +G  G  G PPGD
Sbjct: 597 AAGLPGLHG-PPGD 609


>gi|22027605 alpha 1 type XIII collagen isoform 17 [Homo sapiens]
          Length = 657

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 97/365 (26%), Positives = 127/365 (34%), Gaps = 73/365 (20%)

Query: 227 VPGDGGQK-----EHLPSI-DSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTP 280
           +PG  G+K       LP +   +GEK D G    GG       GLPG P  +G+      
Sbjct: 288 IPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGE------ 341

Query: 281 ASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIA 340
                +G    +GP     +PG   +     +Q P       +G   S G    G +V  
Sbjct: 342 -----AGVDGQVGPPG---QPGDKGERGAAGEQGP-------DGPKGSKGEPGKGEMVDY 386

Query: 341 DLSTDPTELEERALEVAGPDGQASAI----SPASPRRKAADGGHRRALPGCTSLTGETTG 396
           + + +    E R L + GP G    I    +P  P +K   G     LPG         G
Sbjct: 387 NGNINEALQEIRTLALMGPPGLPGQIGPPGAPGIPGQKGEIG-----LPG-------PPG 434

Query: 397 ESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQ 456
             GE G  GK PGD  +GP       PG        G++GH              PG   
Sbjct: 435 HDGEKGPRGK-PGD--MGPPGPQG-PPGKDGPPGVKGENGHPG-----------SPGEKG 479

Query: 457 EEAELG--GQNLERDLEGFRVSPQASVVLEHREIADDPLQEPGAQQGIPDTTSELAGQRD 514
           E+ E G  G   E+   G + +P A V        + P   PG  QG+P    E AG   
Sbjct: 480 EKGETGQAGSPGEKGEAGEKGNPGAEV--PGLPGPEGPPGPPGL-QGVPGPKGE-AGLDG 535

Query: 515 HLPHSADQGTWADSLAVELDFLLDSQIQDALDASDFEAPPEQLFPSGNKPGPCWPGPSSH 574
                  QG   D   + L          A        PP    P G  PGP  P     
Sbjct: 536 AKGEKGFQGEKGDRGPLGL--------PGASGLDGRPGPPGTPGPIG-VPGPAGPKGERG 586

Query: 575 ANGDP 579
           + GDP
Sbjct: 587 SKGDP 591



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 58/194 (29%), Positives = 69/194 (35%), Gaps = 44/194 (22%)

Query: 222 PETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPA 281
           P  D  PG  G+  H  S   +GEK + G  Q G       AG  G P  E  G+P    
Sbjct: 457 PGKDGPPGVKGENGHPGSPGEKGEKGETG--QAGSPGEKGEAGEKGNPGAEVPGLP---- 510

Query: 282 SAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGE-GTHSSLG-CSSLGMVVI 339
             P   P P          PG   QG P P+      G +GE G     G    LG+   
Sbjct: 511 -GPEGPPGP----------PG--LQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGA 557

Query: 340 ADLSTDPTELEERALEVAGPDGQASAI---SPASPRRKAADGGHRRALPGCTSLTGETTG 396
           + L   P           GP G    I    PA P+ +    G     PG T      TG
Sbjct: 558 SGLDGRP-----------GPPGTPGPIGVPGPAGPKGERGSKGD----PGMTG----PTG 598

Query: 397 ESGEAGQDGKPPGD 410
            +G  G  G PPGD
Sbjct: 599 AAGLPGLHG-PPGD 611


>gi|22027603 alpha 1 type XIII collagen isoform 16 [Homo sapiens]
          Length = 660

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 97/365 (26%), Positives = 127/365 (34%), Gaps = 73/365 (20%)

Query: 227 VPGDGGQK-----EHLPSI-DSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTP 280
           +PG  G+K       LP +   +GEK D G    GG       GLPG P  +G+      
Sbjct: 291 IPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGE------ 344

Query: 281 ASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIA 340
                +G    +GP     +PG   +     +Q P       +G   S G    G +V  
Sbjct: 345 -----AGVDGQVGPPG---QPGDKGERGAAGEQGP-------DGPKGSKGEPGKGEMVDY 389

Query: 341 DLSTDPTELEERALEVAGPDGQASAI----SPASPRRKAADGGHRRALPGCTSLTGETTG 396
           + + +    E R L + GP G    I    +P  P +K   G     LPG         G
Sbjct: 390 NGNINEALQEIRTLALMGPPGLPGQIGPPGAPGIPGQKGEIG-----LPG-------PPG 437

Query: 397 ESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQ 456
             GE G  GK PGD  +GP       PG        G++GH              PG   
Sbjct: 438 HDGEKGPRGK-PGD--MGPPGPQG-PPGKDGPPGVKGENGHPG-----------SPGEKG 482

Query: 457 EEAELG--GQNLERDLEGFRVSPQASVVLEHREIADDPLQEPGAQQGIPDTTSELAGQRD 514
           E+ E G  G   E+   G + +P A V        + P   PG  QG+P    E AG   
Sbjct: 483 EKGETGQAGSPGEKGEAGEKGNPGAEV--PGLPGPEGPPGPPGL-QGVPGPKGE-AGLDG 538

Query: 515 HLPHSADQGTWADSLAVELDFLLDSQIQDALDASDFEAPPEQLFPSGNKPGPCWPGPSSH 574
                  QG   D   + L          A        PP    P G  PGP  P     
Sbjct: 539 AKGEKGFQGEKGDRGPLGL--------PGASGLDGRPGPPGTPGPIG-VPGPAGPKGERG 589

Query: 575 ANGDP 579
           + GDP
Sbjct: 590 SKGDP 594



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 58/194 (29%), Positives = 69/194 (35%), Gaps = 44/194 (22%)

Query: 222 PETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPA 281
           P  D  PG  G+  H  S   +GEK + G  Q G       AG  G P  E  G+P    
Sbjct: 460 PGKDGPPGVKGENGHPGSPGEKGEKGETG--QAGSPGEKGEAGEKGNPGAEVPGLP---- 513

Query: 282 SAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGE-GTHSSLG-CSSLGMVVI 339
             P   P P          PG   QG P P+      G +GE G     G    LG+   
Sbjct: 514 -GPEGPPGP----------PG--LQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGA 560

Query: 340 ADLSTDPTELEERALEVAGPDGQASAI---SPASPRRKAADGGHRRALPGCTSLTGETTG 396
           + L   P           GP G    I    PA P+ +    G     PG T      TG
Sbjct: 561 SGLDGRP-----------GPPGTPGPIGVPGPAGPKGERGSKGD----PGMTG----PTG 601

Query: 397 ESGEAGQDGKPPGD 410
            +G  G  G PPGD
Sbjct: 602 AAGLPGLHG-PPGD 614


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.130    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,005,955
Number of Sequences: 37866
Number of extensions: 2301335
Number of successful extensions: 10305
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 78
Number of HSP's successfully gapped in prelim test: 901
Number of HSP's that attempted gapping in prelim test: 7445
Number of HSP's gapped (non-prelim): 2721
length of query: 637
length of database: 18,247,518
effective HSP length: 109
effective length of query: 528
effective length of database: 14,120,124
effective search space: 7455425472
effective search space used: 7455425472
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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