Guide to the Human Genome
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Search of human proteins with 122937273

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|122937273 hypothetical protein LOC131149 [Homo sapiens]
         (477 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|122937273 hypothetical protein LOC131149 [Homo sapiens]           1002   0.0  
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]               261   8e-70
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]          256   3e-68
gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]       251   1e-66
gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]       251   1e-66
gi|56847616 C1q and tumor necrosis factor related protein 9B [Ho...   250   2e-66
gi|65301115 C1q and tumor necrosis factor related protein 9 [Hom...   247   1e-65
gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]      211   1e-54
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     205   6e-53
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   199   6e-51
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   199   6e-51
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   199   6e-51
gi|5803080 macrophage receptor with collagenous structure [Homo ...   199   6e-51
gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]              198   1e-50
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]              197   1e-50
gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [H...   197   2e-50
gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Ho...   197   2e-50
gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Hom...   197   2e-50
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         196   3e-50
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]    196   4e-50
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      196   5e-50
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...   195   9e-50
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...   195   9e-50
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...   195   9e-50
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]   195   9e-50
gi|38570075 collagen, type XXV, alpha 1 isoform 1 [Homo sapiens]      194   1e-49
gi|11386161 alpha 2 type IX collagen [Homo sapiens]                   194   1e-49
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]     194   2e-49
gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]       194   2e-49
gi|22027583 alpha 1 type XIII collagen isoform 7 [Homo sapiens]       194   2e-49

>gi|122937273 hypothetical protein LOC131149 [Homo sapiens]
          Length = 477

 Score = 1002 bits (2590), Expect = 0.0
 Identities = 477/477 (100%), Positives = 477/477 (100%)

Query: 1   MWMFSWLCAILIILAIAGMNTIAKTTPHTKFTKKSEEREMPKGLKPSSGPPPEEEETLFT 60
           MWMFSWLCAILIILAIAGMNTIAKTTPHTKFTKKSEEREMPKGLKPSSGPPPEEEETLFT
Sbjct: 1   MWMFSWLCAILIILAIAGMNTIAKTTPHTKFTKKSEEREMPKGLKPSSGPPPEEEETLFT 60

Query: 61  EMAEMAEPITKPSALDSVFGTATLSPFENFTLDPADFFLNCCDCCSPVPGQKGEPGETGQ 120
           EMAEMAEPITKPSALDSVFGTATLSPFENFTLDPADFFLNCCDCCSPVPGQKGEPGETGQ
Sbjct: 61  EMAEMAEPITKPSALDSVFGTATLSPFENFTLDPADFFLNCCDCCSPVPGQKGEPGETGQ 120

Query: 121 PGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKPGAQGEPGPKGD 180
           PGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKPGAQGEPGPKGD
Sbjct: 121 PGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKPGAQGEPGPKGD 180

Query: 181 KGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGD 240
           KGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGD
Sbjct: 181 KGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGD 240

Query: 241 KGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGP 300
           KGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGP
Sbjct: 241 KGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGP 300

Query: 301 PGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPPPNIPI 360
           PGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPPPNIPI
Sbjct: 301 PGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPPPNIPI 360

Query: 361 KFEKILYNDQGNYSPVTGKFNCSIPGTYVFSYHITVRGRPARISLVAQNKKQFKSRETLY 420
           KFEKILYNDQGNYSPVTGKFNCSIPGTYVFSYHITVRGRPARISLVAQNKKQFKSRETLY
Sbjct: 361 KFEKILYNDQGNYSPVTGKFNCSIPGTYVFSYHITVRGRPARISLVAQNKKQFKSRETLY 420

Query: 421 GQEIDQASLLVILKLSAGDQVWLEVSKDWNGVYVSAEDDSIFTGFLLYPEETSGISP 477
           GQEIDQASLLVILKLSAGDQVWLEVSKDWNGVYVSAEDDSIFTGFLLYPEETSGISP
Sbjct: 421 GQEIDQASLLVILKLSAGDQVWLEVSKDWNGVYVSAEDDSIFTGFLLYPEETSGISP 477


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score =  261 bits (668), Expect = 8e-70
 Identities = 160/408 (39%), Positives = 202/408 (49%), Gaps = 49/408 (12%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGP---------RGYKGEKGLKGERGDQ 160
           G KGEPG  G PG  G  G  G+PG PG  G +GP         RG  GE G  GE+G Q
Sbjct: 296 GAKGEPGTRGPPGLIGPTG-YGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQ 354

Query: 161 GVPGYPGKPGAQGEPG---PKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSP 217
           G+ G PG PG+ G PG   P G KG  G GG  G  G +GD   +   G+ G  G  G P
Sbjct: 355 GLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLP 414

Query: 218 GLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKS 277
           G HG PG  G KGE G  G  G  G  G  G++G  G  G+ G++G  G  G  G  G  
Sbjct: 415 GAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPI 474

Query: 278 GRNGLPGAKGDPGIKGEKGE--LGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRG------ 329
           G  GLPG KG+PG+ G  GE   G PG  GPTGP G  G+ G+ GP G  G  G      
Sbjct: 475 GPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPG 534

Query: 330 ----------------------FKGSK-----GELARVPRSAFSAGLSKPFPPPNIPIKF 362
                                  KG K     GEL+     AF+A L+ PFP   +P+KF
Sbjct: 535 AFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKF 594

Query: 363 EKILYNDQGNYSPVTGKFNCSIPGTYVFSYHITVRGRPARISLVAQNKKQFKSRETLYGQ 422
           ++ LYN    Y+P TG F C + G Y F+YH+ V+G    ++L   N     + +     
Sbjct: 595 DRTLYNGHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKG 654

Query: 423 EIDQASLLVILKLSAGDQVWLEVSKDW-NGVYVSAEDDSIFTGFLLYP 469
            +DQAS   +L+L   DQVW+++  D  NG+Y +    S F+GFLL P
Sbjct: 655 YLDQASGGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLLCP 702



 Score =  179 bits (455), Expect = 4e-45
 Identities = 116/273 (42%), Positives = 139/273 (50%), Gaps = 30/273 (10%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGV-----------VGPQGPRGYKGEKGLKGER 157
           PG KGE G  G PGP+GE G +G  GPPGV            GPQGP G KGE G +G  
Sbjct: 248 PGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPP 307

Query: 158 GDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSP 217
           G  G  GY    G  G PGPKGD+G  G+ G+ G +G  G+   +   GE+G QG  G P
Sbjct: 308 GLIGPTGY----GMPGLPGPKGDRGPAGVPGLLGDRGEPGE---DGEPGEQGPQGLGGPP 360

Query: 218 GLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKG---EGGMKGEKGSKGDSGME 274
           GL G  G  G +G  G KGE G  G  G  G RG +G  G   + G+ GE+G  G  G  
Sbjct: 361 GLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPP 420

Query: 275 GKSGRNGLPG---AKGDPGIK---GEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSR 328
           G +G  G PG     G PG+    G+KG+LG PG  G  GP G  G +G  GP G +G  
Sbjct: 421 GPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLP 480

Query: 329 GFKGSKGELARVPRS--AFSAGLSKPFPPPNIP 359
           G KG  G L   P    A   G + P  PP +P
Sbjct: 481 GLKGEPG-LPGPPGEGRAGEPGTAGPTGPPGVP 512



 Score =  177 bits (449), Expect = 2e-44
 Identities = 120/279 (43%), Positives = 138/279 (49%), Gaps = 34/279 (12%)

Query: 109 PGQKGEPGETGQPGPKG-----EAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVP 163
           PG  G+PG  GQPGP G       G  G PG PG VGP G  G +GE G++G++G +G P
Sbjct: 100 PGM-GKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPP 158

Query: 164 G-----------YPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQG 212
           G            PGKPGAQG PGP G +G  G  G  G  G +G   G+   G+ G  G
Sbjct: 159 GPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRG-LKGDNGVGQPGLPG 217

Query: 213 AMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSG 272
           A G  G  G PG  G  G +G+ G  G  G  GD GE G  G  G  G  G  G KG  G
Sbjct: 218 APGQGGAPGPPGLPGPAG-LGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPG 276

Query: 273 MEGKS--GRNGLPGAKGDPGIKGEKGELGPPGLLGPT--------GPKGDIGNKGVRGPT 322
           ++G    G  GLPG +G  G KGE G  GPPGL+GPT        GPKGD G  GV G  
Sbjct: 277 VDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLL 336

Query: 323 GKKGSRGFKGSKGE-----LARVPRSAFSAGLSKPFPPP 356
           G +G  G  G  GE     L   P    SAGL     PP
Sbjct: 337 GDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPP 375



 Score =  165 bits (417), Expect = 1e-40
 Identities = 110/267 (41%), Positives = 123/267 (46%), Gaps = 40/267 (14%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYP- 166
           +PG+ G  G  G PG +GE G  G PGPPG  G +G  G  G+ GL G  G  G PG P 
Sbjct: 171 IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGV-GQPGLPGAPGQGGAPGPPG 229

Query: 167 -------GKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEK--GDQGAMGSP 217
                  GKPG  G PG  GDKG  G  GV G +G  G        G    G  GA G P
Sbjct: 230 LPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLP 289

Query: 218 GLHGGPGAKGEKGEMGE--------------KGEMGDKGCCGDSGERGGKGQKGEGGMKG 263
           G  G  GAKGE G  G                G  GD+G  G  G  G +G+ GE G  G
Sbjct: 290 GPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPG 349

Query: 264 EKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGP---PGLLGPTGPKGDIGNKGV-- 318
           E+G +G  G  G  G  GLPG +G PG KGE G  GP   PG+ G  GP G  G  GV  
Sbjct: 350 EQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPG 409

Query: 319 ----------RGPTGKKGSRGFKGSKG 335
                      GPTG KG  GF G  G
Sbjct: 410 ERGLPGAHGPPGPTGPKGEPGFTGRPG 436



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 48/158 (30%), Positives = 61/158 (38%), Gaps = 21/158 (13%)

Query: 244 CGDSGERGGKGQKGEGGMKG----------EKGSKGDSGMEGKSGRNGLPGAKGDPGIKG 293
           CG     GG    G GG  G          +KG  G    EGK     +P       +KG
Sbjct: 22  CGPRASSGG----GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKG 77

Query: 294 EKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPF 353
           E G  G PG  GP GP G  G  G+ G  G  G  G  G  G  +R+ ++       K  
Sbjct: 78  EPGPPGKPGPRGPPGPPGFPGKPGM-GKPGLHGQPGPAGPPG-FSRMGKAGPPGLPGKVG 135

Query: 354 PPPNIPIKFEKILYNDQGNYSP-----VTGKFNCSIPG 386
           PP    ++ E  +  DQG   P     + G    +IPG
Sbjct: 136 PPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPG 173


>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
          Length = 680

 Score =  256 bits (654), Expect = 3e-68
 Identities = 162/404 (40%), Positives = 197/404 (48%), Gaps = 43/404 (10%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYP- 166
           +PG KG PG  G  GP G  G  G PG PG+ G +GP G  G  G KGE+G  G+PG P 
Sbjct: 277 IPGTKGLPGAPGIAGPPGPPG-FGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPG 335

Query: 167 --GKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPG 224
             G PG  G  GPKG  G+ GL G KG+ G  G       KGE+G  G+ G PG  G PG
Sbjct: 336 LTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPG 395

Query: 225 AKGEKGEMGEKGEMGDKGCCGD---SGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNG 281
             G KG  G  G  GD G  G     G  G  G KG  G  GE G +G  G+ G  G  G
Sbjct: 396 LDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIG 455

Query: 282 LPGAKGDPGIKGEKGELGPP--------GLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGS 333
            PG  G PG KG+ G  GPP        GL GPTGP G  G +G  G  G  G  G  G 
Sbjct: 456 PPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGP 515

Query: 334 KGE---------------------------LARVPRSAFSAGLSKPFPPPNIPIKFEKIL 366
            G+                           +  +P SAF+  LSK +P    PI F+KIL
Sbjct: 516 PGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMPVSAFTVILSKAYPAIGTPIPFDKIL 575

Query: 367 YNDQGNYSPVTGKFNCSIPGTYVFSYHITVRGRPARISLVAQNKKQFKSRETLYGQEIDQ 426
           YN Q +Y P TG F C IPG Y FSYH+ V+G    + L         + +      +DQ
Sbjct: 576 YNRQQHYDPRTGIFTCQIPGIYYFSYHVHVKGTHVWVGLYKNGTPVMYTYDEYTKGYLDQ 635

Query: 427 ASLLVILKLSAGDQVWLEV-SKDWNGVYVSAEDDSIFTGFLLYP 469
           AS   I+ L+  DQVWL++ + + NG+Y S    S F+GFL+ P
Sbjct: 636 ASGSAIIDLTENDQVWLQLPNAESNGLYSSEYVHSSFSGFLVAP 679



 Score =  191 bits (485), Expect = 1e-48
 Identities = 117/280 (41%), Positives = 140/280 (50%), Gaps = 28/280 (10%)

Query: 107 PVPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGL--------KGERG 158
           P  G++GE G  GQPG KG+ G  G  GP G  GPQGP G +G +G+         G+ G
Sbjct: 217 PGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPG 276

Query: 159 DQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPG 218
             G  G PG PG  G PGP G  G  GL G+KG++G  G   G   KGE+G  G  G PG
Sbjct: 277 IPGTKGLPGAPGIAGPPGPPG-FGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPG 335

Query: 219 LHGGP------GAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSG 272
           L G P      G KG  G  G  G  G+ G  G +G  G KG++G  G  G+ G  G  G
Sbjct: 336 LTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPG 395

Query: 273 MEGKSGRNGLPGAKGDPGIKGEKGELGP---------PGLLGPTGPKGDIGNKGVRGPTG 323
           ++G  G  GLPG KGDPG+ G  G  GP         PG  G  GP+G  G  G RGP G
Sbjct: 396 LDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIG 455

Query: 324 KKGSRGFKGSKGELARV----PRSAFSAGLSKPFPPPNIP 359
             G  GF GSKG+        P    + GL+ P  PP  P
Sbjct: 456 PPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPP 495



 Score =  176 bits (445), Expect = 5e-44
 Identities = 116/267 (43%), Positives = 135/267 (50%), Gaps = 18/267 (6%)

Query: 109 PGQKGEPGETGQPGPK--GEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYP 166
           PG +GEPG  G PGP   G+ G  G+PG PG  GP GP+G  G  GL G RG  G PG P
Sbjct: 88  PGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIP 147

Query: 167 GKPG--AQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPG 224
           G  G    G+PG +G  G  G  G  G+KG+ G    N  KGE G  GA G PG  G PG
Sbjct: 148 GPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMG-YGAPGRPGERGLPG 206

Query: 225 AKGEKGE-----MGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGR 279
            +G  G      +G++GE G  G  G  G+RG  G+ G  G  G +G  G+ G EG  G+
Sbjct: 207 PQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEG-IGK 265

Query: 280 NGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGD-----IGNKGVRGPTGKKGSRGFKGSK 334
            G  GA G PGI G KG  G PG+ GP GP G       G KG RGP G  G  G KG +
Sbjct: 266 PGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQ 325

Query: 335 GE--LARVPRSAFSAGLSKPFPPPNIP 359
           G   L   P      G   P  P  IP
Sbjct: 326 GPAGLPGKPGLTGPPGNMGPQGPKGIP 352



 Score =  172 bits (435), Expect = 8e-43
 Identities = 117/305 (38%), Positives = 142/305 (46%), Gaps = 61/305 (20%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGI------PGPPGVVGP-----------QGPRGYKGE 150
           VPG  G+PGE G  GPKG+ G  G+      PGPPG+ GP           QGP G  G 
Sbjct: 110 VPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGP 169

Query: 151 KGLKGERGDQGVPGY-----------PGKPGAQGEPGPKGDK--------GNIGLGGVKG 191
           +G  GE+G  GVPG            PG+PG +G PGP+G          G  G  GV G
Sbjct: 170 RGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPG 229

Query: 192 QKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERG 251
           Q G KGD      +G  G+ G +G PG  G PG +G +G +G+ G  G  G  G  G +G
Sbjct: 230 QPGIKGD------RGFPGEMGPIGPPGPQGPPGERGPEG-IGKPGAAGAPGQPGIPGTKG 282

Query: 252 GKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGE---------LGPPG 302
             G  G  G  G  G  G  G+ G  G  G  G  G PG KGE+G           GPPG
Sbjct: 283 LPGAPGIAGPPGPPGF-GKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPG 341

Query: 303 LLGPTGPKGDIGNKGVRGP---TGKKGSRGFKGSKGELAR-----VPRSAFSAGLSKPFP 354
            +GP GPKG  G+ G+ GP   TG  G  G+ G+KGE         P      GL  P  
Sbjct: 342 NMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKG 401

Query: 355 PPNIP 359
            P +P
Sbjct: 402 NPGLP 406



 Score =  127 bits (318), Expect = 3e-29
 Identities = 79/201 (39%), Positives = 97/201 (48%), Gaps = 30/201 (14%)

Query: 157 RGDQGVPGYPGKPGAQGEPGPKGDKGNIGLG--GVKGQKGSKGDTCGNCTKGEKGDQGAM 214
           RG+QG PG PG  G +G PGP G  G  G G  G++G+ G  G               A+
Sbjct: 56  RGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPP----------GPSAV 105

Query: 215 GSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMK--GEKGSKGDSG 272
           G PG+ G PG  GE+G  G KG++G  G  G  G  G  G  G  G+   G+ G +G +G
Sbjct: 106 GKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTG 165

Query: 273 MEGKSGRNGLPGAKGDPGIKGEKGEL-----------GPPGLLGPTGPK-----GDIGNK 316
             G  G  G  GA G PG+ G+KGE+           G PG  GPTGP      G  G  
Sbjct: 166 APGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGEN 225

Query: 317 GVRGPTGKKGSRGFKGSKGEL 337
           GV G  G KG RGF G  G +
Sbjct: 226 GVPGQPGIKGDRGFPGEMGPI 246



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 34/103 (33%), Positives = 39/103 (37%), Gaps = 26/103 (25%)

Query: 276 KSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKG-------------------DIGNK 316
           KS    + G +G PG  G  G  G PG  GP G  G                    +G  
Sbjct: 49  KSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKP 108

Query: 317 GVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPPPNIP 359
           GV G  GK G RG  G KG++         AGL  P  PP  P
Sbjct: 109 GVPGLPGKPGERGPYGPKGDVG-------PAGLPGPRGPPGPP 144


>gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score =  251 bits (640), Expect = 1e-66
 Identities = 160/426 (37%), Positives = 210/426 (49%), Gaps = 65/426 (15%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVG--------PQGPRGYKGEKGLKGERGDQ 160
           PGQ G PG+ G PG KGE G  G+PGPPG+ G        P+G RG  G  G  G RG++
Sbjct: 318 PGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEK 377

Query: 161 G------VPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAM 214
           G      + G PG+PG  G PGP G  G IG  G KG+ G  G       KGE G QG  
Sbjct: 378 GPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFP 437

Query: 215 GSPGLHGG---PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDS 271
           G PG  G    PG +G  G +G KGE G KG  G  G  G  G KGE G+ G++G +G  
Sbjct: 438 GKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPP 497

Query: 272 GMEGKSGRNG------LPGAKGDPGIKGEKG--ELGPPGLLGPTGPKGDIGNKGVRGPTG 323
           G+ G  G +G      +PG KG+PG+ G  G   +G PG+ G  GP G  G  G +G  G
Sbjct: 498 GIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPG 557

Query: 324 KKGSRGFKGSKGELARVPRS---------------------------------------A 344
             G  G  G  G  A +P +                                       A
Sbjct: 558 LPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPA 617

Query: 345 FSAGLSKPFPPPNIPIKFEKILYNDQGNYSPVTGKFNCSIPGTYVFSYHITVRGRPARIS 404
           F+A L+ PFPP   P+KF K+LYN + NY+P TG F C +PG Y F+YH+  +G    ++
Sbjct: 618 FTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGVYYFAYHVHCKGGNVWVA 677

Query: 405 LVAQNKKQFKSRETLYGQEIDQASLLVILKLSAGDQVWLEV-SKDWNGVYVSAEDDSIFT 463
           L   N+    + +      +DQAS   +L L  GD+V+L++ S+   G+Y      S F+
Sbjct: 678 LFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPSEQAAGLYAGQYVHSSFS 737

Query: 464 GFLLYP 469
           G+LLYP
Sbjct: 738 GYLLYP 743



 Score =  174 bits (440), Expect = 2e-43
 Identities = 116/288 (40%), Positives = 138/288 (47%), Gaps = 43/288 (14%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVP---- 163
           +PG KG+PG  G PG     G  G+PG PG  G  G  G KGE G KGE G  G+P    
Sbjct: 142 IPGIKGKPGPQGYPG----VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQG 197

Query: 164 ----------GYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNC--TKGEKGDQ 211
                     G PG PG  G+PGPKGD+G  GL G +G +G KGD         G KG  
Sbjct: 198 PPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPP 257

Query: 212 G-----------AMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERG-------GK 253
           G            +G PG+ G PG +G  G+ G  GE G +G  G  G +G       GK
Sbjct: 258 GMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGK 317

Query: 254 -GQKGEGGMKGEKGSKGDSGMEGKSGRNGLP--GAKGDPGIKGEKGELGPPGLLGPTGPK 310
            GQ G  G  G  G KG+ G+ G  G  GLP  G  G PG KG++G  G PG LGP G K
Sbjct: 318 PGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEK 377

Query: 311 GDIGNKGVRGPTGKKGSRGFKGSKGELARV--PRSAFSAGLSKPFPPP 356
           G IG  G+ GP G+ G  G  G  G    +  P      G+  P  PP
Sbjct: 378 GPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPP 425



 Score =  171 bits (433), Expect = 1e-42
 Identities = 107/260 (41%), Positives = 133/260 (51%), Gaps = 15/260 (5%)

Query: 107 PVPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGY--------KGEKGLKGERG 158
           P  G+ G PG  GQPGPKG+ G  G+PGP G+ GP+G +G+        KG  G+ G  G
Sbjct: 205 PGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPG 264

Query: 159 DQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPG 218
             G+PG  GKPG  G PGP+G  G  G  G  G +G  G        G  G  G  G  G
Sbjct: 265 PVGLPGV-GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPG-IGKPGQDG 322

Query: 219 LHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSG 278
           + G PG  G KGE G  G  G  G  G  G+ G  G KG+ GM G  G+ G  G +G  G
Sbjct: 323 IPGQPGFPGGKGEQGLPGLPGPPGLPG-IGKPGFPGPKGDRGMGGVPGALGPRGEKGPIG 381

Query: 279 RNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGD---IGNKGVRGPTGKKGSRGFKGSKG 335
             G+ G  G+PG+ G  G +GPPG +G  GPKG+   +G +G  GP G+ G +GF G  G
Sbjct: 382 APGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPG 441

Query: 336 ELARVPRSAFSAGLSKPFPP 355
            L  V       GL  P  P
Sbjct: 442 FLGEVGPPGM-RGLPGPIGP 460



 Score =  148 bits (373), Expect = 1e-35
 Identities = 106/270 (39%), Positives = 128/270 (47%), Gaps = 38/270 (14%)

Query: 120 QPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK--PGAQGEPGP 177
           QP P+   G   +P     +     RG +G +G  G RG  G PG PG   PG +G+PGP
Sbjct: 94  QPAPR--MGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGP 151

Query: 178 K--------------GDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGP 223
           +              G  G +G+ G KG+ G KG+       G +G  G  G PG+ G P
Sbjct: 152 QGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI-GKP 210

Query: 224 GAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLP 283
           G  G  G+ G KG+ G KG  G  G RG KG KG  GM G  G KG  GM G  G  GLP
Sbjct: 211 GGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGVKGPPGMHGPPGPVGLP 269

Query: 284 GAKGDPGI---KGEKGELGPPGLLGPTGPKGDIGNKGVRGP-----------TGKKGSRG 329
           G  G PG+    G +G LG PG  G  GP+G IG  GV+GP            G  G  G
Sbjct: 270 GV-GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPG 328

Query: 330 FKGSKGE--LARVPRSAFSAGLSKP-FPPP 356
           F G KGE  L  +P      G+ KP FP P
Sbjct: 329 FPGGKGEQGLPGLPGPPGLPGIGKPGFPGP 358



 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 59/154 (38%), Positives = 72/154 (46%), Gaps = 20/154 (12%)

Query: 224 GAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLP 283
           G +G +GE G +G  G  G  G  G  G KG+ G  G  G  G  G  GM GK G  G+P
Sbjct: 118 GEQGPRGEPGPRGPPGPPGLPGH-GIPGIKGKPGPQGYPGV-GKPGMPGMPGKPGAMGMP 175

Query: 284 GAKGDPGIKGEKGELGPPGLLGPTGP--------------KGDIGNKGVRGPTGKKGSRG 329
           GAKG+ G KGE G +G PG  GP GP               G  G KG RGP G  G +G
Sbjct: 176 GAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQG 235

Query: 330 FKGSKGE----LARVPRSAFSAGLSKPFPPPNIP 359
            +G KG+    +   P      G+  P  P  +P
Sbjct: 236 LRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLP 269



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 39/113 (34%), Positives = 44/113 (38%), Gaps = 40/113 (35%)

Query: 108 VPGQKGEPGETGQPG--------------PKGEAGNLGI---PGPPGVVGPQGPRGYKGE 150
           +PG KGEPG  G PG              P G+ G LG    PG PG  GP GP G    
Sbjct: 514 IPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAV 573

Query: 151 KGLKGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVK------GQKGSKG 197
                          P  P  QGE  P  D G +G+ GVK       +KG  G
Sbjct: 574 --------------MPPTPPPQGEYLP--DMG-LGIDGVKPPHAYGAKKGKNG 609


>gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score =  251 bits (640), Expect = 1e-66
 Identities = 160/426 (37%), Positives = 210/426 (49%), Gaps = 65/426 (15%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVG--------PQGPRGYKGEKGLKGERGDQ 160
           PGQ G PG+ G PG KGE G  G+PGPPG+ G        P+G RG  G  G  G RG++
Sbjct: 318 PGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEK 377

Query: 161 G------VPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAM 214
           G      + G PG+PG  G PGP G  G IG  G KG+ G  G       KGE G QG  
Sbjct: 378 GPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFP 437

Query: 215 GSPGLHGG---PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDS 271
           G PG  G    PG +G  G +G KGE G KG  G  G  G  G KGE G+ G++G +G  
Sbjct: 438 GKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPP 497

Query: 272 GMEGKSGRNG------LPGAKGDPGIKGEKG--ELGPPGLLGPTGPKGDIGNKGVRGPTG 323
           G+ G  G +G      +PG KG+PG+ G  G   +G PG+ G  GP G  G  G +G  G
Sbjct: 498 GIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPG 557

Query: 324 KKGSRGFKGSKGELARVPRS---------------------------------------A 344
             G  G  G  G  A +P +                                       A
Sbjct: 558 LPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPA 617

Query: 345 FSAGLSKPFPPPNIPIKFEKILYNDQGNYSPVTGKFNCSIPGTYVFSYHITVRGRPARIS 404
           F+A L+ PFPP   P+KF K+LYN + NY+P TG F C +PG Y F+YH+  +G    ++
Sbjct: 618 FTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGVYYFAYHVHCKGGNVWVA 677

Query: 405 LVAQNKKQFKSRETLYGQEIDQASLLVILKLSAGDQVWLEV-SKDWNGVYVSAEDDSIFT 463
           L   N+    + +      +DQAS   +L L  GD+V+L++ S+   G+Y      S F+
Sbjct: 678 LFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPSEQAAGLYAGQYVHSSFS 737

Query: 464 GFLLYP 469
           G+LLYP
Sbjct: 738 GYLLYP 743



 Score =  174 bits (440), Expect = 2e-43
 Identities = 116/288 (40%), Positives = 138/288 (47%), Gaps = 43/288 (14%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVP---- 163
           +PG KG+PG  G PG     G  G+PG PG  G  G  G KGE G KGE G  G+P    
Sbjct: 142 IPGIKGKPGPQGYPG----VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQG 197

Query: 164 ----------GYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNC--TKGEKGDQ 211
                     G PG PG  G+PGPKGD+G  GL G +G +G KGD         G KG  
Sbjct: 198 PPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPP 257

Query: 212 G-----------AMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERG-------GK 253
           G            +G PG+ G PG +G  G+ G  GE G +G  G  G +G       GK
Sbjct: 258 GMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGK 317

Query: 254 -GQKGEGGMKGEKGSKGDSGMEGKSGRNGLP--GAKGDPGIKGEKGELGPPGLLGPTGPK 310
            GQ G  G  G  G KG+ G+ G  G  GLP  G  G PG KG++G  G PG LGP G K
Sbjct: 318 PGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEK 377

Query: 311 GDIGNKGVRGPTGKKGSRGFKGSKGELARV--PRSAFSAGLSKPFPPP 356
           G IG  G+ GP G+ G  G  G  G    +  P      G+  P  PP
Sbjct: 378 GPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPP 425



 Score =  171 bits (433), Expect = 1e-42
 Identities = 107/260 (41%), Positives = 133/260 (51%), Gaps = 15/260 (5%)

Query: 107 PVPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGY--------KGEKGLKGERG 158
           P  G+ G PG  GQPGPKG+ G  G+PGP G+ GP+G +G+        KG  G+ G  G
Sbjct: 205 PGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPG 264

Query: 159 DQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPG 218
             G+PG  GKPG  G PGP+G  G  G  G  G +G  G        G  G  G  G  G
Sbjct: 265 PVGLPGV-GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPG-IGKPGQDG 322

Query: 219 LHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSG 278
           + G PG  G KGE G  G  G  G  G  G+ G  G KG+ GM G  G+ G  G +G  G
Sbjct: 323 IPGQPGFPGGKGEQGLPGLPGPPGLPG-IGKPGFPGPKGDRGMGGVPGALGPRGEKGPIG 381

Query: 279 RNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGD---IGNKGVRGPTGKKGSRGFKGSKG 335
             G+ G  G+PG+ G  G +GPPG +G  GPKG+   +G +G  GP G+ G +GF G  G
Sbjct: 382 APGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPG 441

Query: 336 ELARVPRSAFSAGLSKPFPP 355
            L  V       GL  P  P
Sbjct: 442 FLGEVGPPGM-RGLPGPIGP 460



 Score =  148 bits (373), Expect = 1e-35
 Identities = 106/270 (39%), Positives = 128/270 (47%), Gaps = 38/270 (14%)

Query: 120 QPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK--PGAQGEPGP 177
           QP P+   G   +P     +     RG +G +G  G RG  G PG PG   PG +G+PGP
Sbjct: 94  QPAPR--MGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGP 151

Query: 178 K--------------GDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGP 223
           +              G  G +G+ G KG+ G KG+       G +G  G  G PG+ G P
Sbjct: 152 QGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI-GKP 210

Query: 224 GAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLP 283
           G  G  G+ G KG+ G KG  G  G RG KG KG  GM G  G KG  GM G  G  GLP
Sbjct: 211 GGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGVKGPPGMHGPPGPVGLP 269

Query: 284 GAKGDPGI---KGEKGELGPPGLLGPTGPKGDIGNKGVRGP-----------TGKKGSRG 329
           G  G PG+    G +G LG PG  G  GP+G IG  GV+GP            G  G  G
Sbjct: 270 GV-GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPG 328

Query: 330 FKGSKGE--LARVPRSAFSAGLSKP-FPPP 356
           F G KGE  L  +P      G+ KP FP P
Sbjct: 329 FPGGKGEQGLPGLPGPPGLPGIGKPGFPGP 358



 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 59/154 (38%), Positives = 72/154 (46%), Gaps = 20/154 (12%)

Query: 224 GAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLP 283
           G +G +GE G +G  G  G  G  G  G KG+ G  G  G  G  G  GM GK G  G+P
Sbjct: 118 GEQGPRGEPGPRGPPGPPGLPGH-GIPGIKGKPGPQGYPGV-GKPGMPGMPGKPGAMGMP 175

Query: 284 GAKGDPGIKGEKGELGPPGLLGPTGP--------------KGDIGNKGVRGPTGKKGSRG 329
           GAKG+ G KGE G +G PG  GP GP               G  G KG RGP G  G +G
Sbjct: 176 GAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQG 235

Query: 330 FKGSKGE----LARVPRSAFSAGLSKPFPPPNIP 359
            +G KG+    +   P      G+  P  P  +P
Sbjct: 236 LRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLP 269



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 39/113 (34%), Positives = 44/113 (38%), Gaps = 40/113 (35%)

Query: 108 VPGQKGEPGETGQPG--------------PKGEAGNLGI---PGPPGVVGPQGPRGYKGE 150
           +PG KGEPG  G PG              P G+ G LG    PG PG  GP GP G    
Sbjct: 514 IPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAV 573

Query: 151 KGLKGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVK------GQKGSKG 197
                          P  P  QGE  P  D G +G+ GVK       +KG  G
Sbjct: 574 --------------MPPTPPPQGEYLP--DMG-LGIDGVKPPHAYGAKKGKNG 609


>gi|56847616 C1q and tumor necrosis factor related protein 9B [Homo
           sapiens]
          Length = 333

 Score =  250 bits (638), Expect = 2e-66
 Identities = 140/322 (43%), Positives = 183/322 (56%), Gaps = 17/322 (5%)

Query: 154 KGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGA 213
           +G  G  G PG+ G PG  G  G KGDKG+ G  G  G  G  G      T GEKG++GA
Sbjct: 25  QGHPGIPGNPGHNGLPGRDGRDGAKGDKGDAGEPGCPGSPGKDG------TSGEKGERGA 78

Query: 214 MGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGM 273
            G         AKG KG+ G +G  G  G  G +G  G KG +GE G +G+KG+KGD G 
Sbjct: 79  DGKVE------AKGIKGDQGSRGSPGKHGPKGLAGPMGEKGLRGETGPQGQKGNKGDVGP 132

Query: 274 EGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGS 333
            G  G  G  G  G  G+ G  G +G PG  G  GP G  G  GVRG  G KG RG KG 
Sbjct: 133 TGPEGPRGNIGPLGPTGLPGPMGPIGKPGPKGEAGPTGPQGEPGVRGIRGWKGDRGEKGK 192

Query: 334 KGELARVPRSAFSAGLS--KPFPPPNIPIKFEKILYNDQGNYSPVTGKFNCSIPGTYVFS 391
            GE   +P+SAF+ GL+    FP  ++PIKF+KILYN+  +Y    GKF C I G Y F+
Sbjct: 193 IGETLVLPKSAFTVGLTVLSKFPSSDVPIKFDKILYNEFNHYDTAVGKFTCHIAGVYYFT 252

Query: 392 YHITVRGRPARISLVAQNKKQFKSRETLYGQEIDQASLLVILKLSAGDQVWLEVS--KDW 449
           YHITV  R  ++SLV    K   +R+     E DQAS  ++L+L  GD++WL+V+  + +
Sbjct: 253 YHITVFSRNVQVSLVKNGVKILHTRDAYVSSE-DQASGSIVLQLKLGDEMWLQVTGGERF 311

Query: 450 NGVYVSAEDDSIFTGFLLYPEE 471
           NG++   +DD+ FTGFLL+  +
Sbjct: 312 NGLFADEDDDTTFTGFLLFSSQ 333



 Score =  132 bits (332), Expect = 7e-31
 Identities = 75/164 (45%), Positives = 93/164 (56%), Gaps = 9/164 (5%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKG------LKGERGDQGV 162
           PG  G PG  G+ G KG+ G+ G PG PG  G  G  G KGE+G       KG +GDQG 
Sbjct: 34  PGHNGLPGRDGRDGAKGDKGDAGEPGCPGSPGKDGTSGEKGERGADGKVEAKGIKGDQGS 93

Query: 163 PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
            G PGK G +G  GP G+KG  G  G +GQKG+KGD      +G +G+ G +G  GL   
Sbjct: 94  RGSPGKHGPKGLAGPMGEKGLRGETGPQGQKGNKGDVGPTGPEGPRGNIGPLGPTGL--- 150

Query: 223 PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKG 266
           PG  G  G+ G KGE G  G  G+ G RG +G KG+ G KG+ G
Sbjct: 151 PGPMGPIGKPGPKGEAGPTGPQGEPGVRGIRGWKGDRGEKGKIG 194



 Score =  100 bits (249), Expect = 3e-21
 Identities = 57/128 (44%), Positives = 70/128 (54%), Gaps = 3/128 (2%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           G+KGE G  G+   KG  G+ G  G PG  GP+G  G  GEKGL+GE G QG  G  G  
Sbjct: 71  GEKGERGADGKVEAKGIKGDQGSRGSPGKHGPKGLAGPMGEKGLRGETGPQGQKGNKGDV 130

Query: 170 GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
           G  G  GP+G+ G +G  G+ G  G  G       KGE G  G  G PG+ G  G KG++
Sbjct: 131 GPTGPEGPRGNIGPLGPTGLPGPMGPIGKP---GPKGEAGPTGPQGEPGVRGIRGWKGDR 187

Query: 230 GEMGEKGE 237
           GE G+ GE
Sbjct: 188 GEKGKIGE 195


>gi|65301115 C1q and tumor necrosis factor related protein 9 [Homo
           sapiens]
          Length = 333

 Score =  247 bits (631), Expect = 1e-65
 Identities = 140/319 (43%), Positives = 182/319 (57%), Gaps = 17/319 (5%)

Query: 154 KGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGA 213
           +G  G  G PG+ G PG  G  G KGDKG+ G  G  G  G  G      T GEKG++GA
Sbjct: 25  QGHPGIPGNPGHNGLPGRDGRDGAKGDKGDAGEPGRPGSPGKDG------TSGEKGERGA 78

Query: 214 MGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGM 273
            G         AKG KG+ G +G  G  G  G +G  G KG +GE G +G+KG+KGD G 
Sbjct: 79  DGKVE------AKGIKGDQGSRGSPGKHGPKGLAGPMGEKGLRGETGPQGQKGNKGDVGP 132

Query: 274 EGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGS 333
            G  G  G  G  G  G+ G  G +G PG  G  GP G  G  GVRG  G KG RG KG 
Sbjct: 133 TGPEGPRGNIGPLGPTGLPGPMGPIGKPGPKGEAGPTGPQGEPGVRGIRGWKGDRGEKGK 192

Query: 334 KGELARVPRSAFSAGLS--KPFPPPNIPIKFEKILYNDQGNYSPVTGKFNCSIPGTYVFS 391
            GE   +P+SAF+ GL+    FP  ++PIKF+KILYN+  +Y    GKF C I G Y F+
Sbjct: 193 IGETLVLPKSAFTVGLTVLSKFPSSDMPIKFDKILYNEFNHYDTAAGKFTCHIAGVYYFT 252

Query: 392 YHITVRGRPARISLVAQNKKQFKSRETLYGQEIDQASLLVILKLSAGDQVWLEVS--KDW 449
           YHITV  R  ++SLV    K   +++     E DQAS  ++L+L  GD+VWL+V+  + +
Sbjct: 253 YHITVFSRNVQVSLVKNGVKILHTKDAYMSSE-DQASGGIVLQLKLGDEVWLQVTGGERF 311

Query: 450 NGVYVSAEDDSIFTGFLLY 468
           NG++   +DD+ FTGFLL+
Sbjct: 312 NGLFADEDDDTTFTGFLLF 330



 Score =  132 bits (333), Expect = 5e-31
 Identities = 75/164 (45%), Positives = 93/164 (56%), Gaps = 9/164 (5%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKG------LKGERGDQGV 162
           PG  G PG  G+ G KG+ G+ G PG PG  G  G  G KGE+G       KG +GDQG 
Sbjct: 34  PGHNGLPGRDGRDGAKGDKGDAGEPGRPGSPGKDGTSGEKGERGADGKVEAKGIKGDQGS 93

Query: 163 PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
            G PGK G +G  GP G+KG  G  G +GQKG+KGD      +G +G+ G +G  GL   
Sbjct: 94  RGSPGKHGPKGLAGPMGEKGLRGETGPQGQKGNKGDVGPTGPEGPRGNIGPLGPTGL--- 150

Query: 223 PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKG 266
           PG  G  G+ G KGE G  G  G+ G RG +G KG+ G KG+ G
Sbjct: 151 PGPMGPIGKPGPKGEAGPTGPQGEPGVRGIRGWKGDRGEKGKIG 194



 Score =  100 bits (249), Expect = 3e-21
 Identities = 57/128 (44%), Positives = 70/128 (54%), Gaps = 3/128 (2%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           G+KGE G  G+   KG  G+ G  G PG  GP+G  G  GEKGL+GE G QG  G  G  
Sbjct: 71  GEKGERGADGKVEAKGIKGDQGSRGSPGKHGPKGLAGPMGEKGLRGETGPQGQKGNKGDV 130

Query: 170 GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
           G  G  GP+G+ G +G  G+ G  G  G       KGE G  G  G PG+ G  G KG++
Sbjct: 131 GPTGPEGPRGNIGPLGPTGLPGPMGPIGKP---GPKGEAGPTGPQGEPGVRGIRGWKGDR 187

Query: 230 GEMGEKGE 237
           GE G+ GE
Sbjct: 188 GEKGKIGE 195


>gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]
          Length = 957

 Score =  211 bits (537), Expect = 1e-54
 Identities = 112/234 (47%), Positives = 138/234 (58%), Gaps = 6/234 (2%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG- 167
           PG  G+PG+ G+PG +G AG  G+PG PG+ G +G  GYKGE G  G++GD+G+PG+PG 
Sbjct: 466 PGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGL 525

Query: 168 --KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGA 225
              PG++GE G KGDKG+ G  G KG KG KG+       G  G+ G  G  GL G PG 
Sbjct: 526 HGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGF 585

Query: 226 KGEKGE---MGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGL 282
           KGE G     G+ G  G+ G  G  G RG  GQKGE G  G++G KG  GM G  G NG 
Sbjct: 586 KGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGS 645

Query: 283 PGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
           PG  G PG KG KGE G  G+ G +G KG+ G  G  G  G  G  G +G KG+
Sbjct: 646 PGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGD 699



 Score =  190 bits (483), Expect = 2e-48
 Identities = 106/238 (44%), Positives = 127/238 (53%), Gaps = 12/238 (5%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           G KG PG  G+ G KGE GN G PG PG  G  G  G  G  G  G +G+ G PG PG+ 
Sbjct: 539 GDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQD 598

Query: 170 GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
           G +GEPG  G  GN GL G KG+ G  G        G  G  G+ GSPG  G PG+KG K
Sbjct: 599 GTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSK 658

Query: 230 GE------MGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLP 283
           GE       G  G  G+ G  G  GE G  G  G  G KG+KG++G+ G++G+ G NG  
Sbjct: 659 GEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQ 718

Query: 284 GAKGDPGI------KGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
           G  G  GI      KGE+GE G PG+ G  G KG+ G  G+ GP G KG  G  G +G
Sbjct: 719 GIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQG 776



 Score =  188 bits (478), Expect = 8e-48
 Identities = 106/244 (43%), Positives = 133/244 (54%), Gaps = 12/244 (4%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
           PG+ G+ G  G PG KGEAG+ G PG  G  G  G  G+ G +GL G++G+ G PG  GK
Sbjct: 571 PGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGK 630

Query: 169 PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGE 228
            GA G PG  G  G+ G  G  G KGSKG         E G QG  G+ GL G PGA G 
Sbjct: 631 KGAPGMPGLMGSNGSPGQPGTPGSKGSKG---------EPGIQGMPGASGLKGEPGATGS 681

Query: 229 KGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGD 288
            GE G  G  G +G  GD G +G KG +G+ G  G +G  G  G++G  G  G  G KG+
Sbjct: 682 PGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGE 741

Query: 289 PGIKG---EKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAF 345
           PG++G    KGE G  GL+GP GPKG  G+ G +GP G  G  G + S+  + +V     
Sbjct: 742 PGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVI 801

Query: 346 SAGL 349
            A L
Sbjct: 802 RAQL 805



 Score =  185 bits (470), Expect = 7e-47
 Identities = 103/222 (46%), Positives = 121/222 (54%), Gaps = 9/222 (4%)

Query: 115 PGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKPGAQGE 174
           PG+ G  GPKG+ G  G PG PG  G  G  GY+G  G  G  G  G+ G  G PG +GE
Sbjct: 448 PGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGE 507

Query: 175 PGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGE 234
           PG  GDKG+ GL G  G  G  G      +KGE G +G  GSPG +G  GAKGEKG  G 
Sbjct: 508 PGRDGDKGDRGLPGFPGLHGMPG------SKGEMGAKGDKGSPGFYGKKGAKGEKGNAGF 561

Query: 235 KGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGE 294
            G  G     G+ G  G  G  G  G KGE GS G  G +G  G  G+PG  G+ G+ G+
Sbjct: 562 PGLPGP---AGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQ 618

Query: 295 KGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
           KGE+GPPG  G  G  G  G  G  G  G+ G+ G KGSKGE
Sbjct: 619 KGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGE 660



 Score =  169 bits (428), Expect = 5e-42
 Identities = 101/271 (37%), Positives = 129/271 (47%), Gaps = 46/271 (16%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
           PG +G  G+ G+ GP G+ G  G PG PG++G  G  G  G  G KG +G+ G+ G PG 
Sbjct: 610 PGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGA 669

Query: 169 PGAQGEPGPKGDKGN---IGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGA 225
            G +GEPG  G  G    +GL G++G+KG KG+      +G+KG+ G  G PG  G  G 
Sbjct: 670 SGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGH 729

Query: 226 KGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGS---KGDSGMEGKSGR--- 279
            G KGE GEKGE G +G  G  GE G  G  G  G KG+ G    +G  G++GK GR   
Sbjct: 730 HGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFS 789

Query: 280 ----------------------------------NGLPGAKGDPGIKGEKGELGPPGLLG 305
                                             +G PG  G PG  G +G  G PGL G
Sbjct: 790 EQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPG 849

Query: 306 PTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
             G  G +G   V G  G +G +G  G  GE
Sbjct: 850 RDGVPGLVG---VPGRPGVRGLKGLPGRNGE 877



 Score =  151 bits (382), Expect = 1e-36
 Identities = 100/276 (36%), Positives = 129/276 (46%), Gaps = 50/276 (18%)

Query: 110 GQKGEPGETGQPGP---KGEAGNLGIPGPPG------VVGPQGPRGYKGEKGLKGERGDQ 160
           G KGEPG  G PG    KGE G  G PG PG      + G +G +G +GEKG++G++G+ 
Sbjct: 656 GSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGEN 715

Query: 161 GVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLH 220
           G  G PG+ G QG  G KG++G  G  GV+G  GSKG++  +   G  G +G  G PG  
Sbjct: 716 GRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQ 775

Query: 221 GGPGAKGEKGE---------------------MGEKGE-------MGDKGCCGDSGERGG 252
           G PG  G+ G                      + + G        +   G  G  G  G 
Sbjct: 776 GPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGP 835

Query: 253 KGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEK--------GELGPPGLL 304
            G +G  G+ G  G  G  G+ G  GR G+ G KG PG  GEK        GE GPPG  
Sbjct: 836 IGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPP 895

Query: 305 GPTGP-----KGDIGNKGVRGPTGKKGSRGFKGSKG 335
           GP GP     +G  G+ G+ G  G  G  G +G  G
Sbjct: 896 GPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPG 931



 Score =  141 bits (356), Expect = 1e-33
 Identities = 90/221 (40%), Positives = 108/221 (48%), Gaps = 26/221 (11%)

Query: 121 PGPKGEAGNLGIPGPPGVVGPQGPRGYK-GEKGLKGERGDQGVPGYPGKPGAQGEPGPKG 179
           PG  GE  N    GP  V     P     G+ GL+G +GD G+PG PG PG  G+ G  G
Sbjct: 424 PGFNGECLN----GPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPG 479

Query: 180 DKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMG 239
            +G  G  GV G  G                QGA G PG  G PG  G+KG+ G  G  G
Sbjct: 480 YQGIAGTPGVPGSPGI---------------QGARGLPGYKGEPGRDGDKGDRGLPGFPG 524

Query: 240 DKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELG 299
             G  G  GE G KG KG  G  G+KG+KG+   +G +G  GLPG  G+PG  G+ G +G
Sbjct: 525 LHGMPGSKGEMGAKGDKGSPGFYGKKGAKGE---KGNAGFPGLPGPAGEPGRHGKDGLMG 581

Query: 300 PPGLLGPTGPKGDIGNKGVRGP---TGKKGSRGFKGSKGEL 337
            PG  G  G  G  G  G RG     G  G+RG  G KGE+
Sbjct: 582 SPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEI 622



 Score =  125 bits (314), Expect = 8e-29
 Identities = 87/238 (36%), Positives = 111/238 (46%), Gaps = 30/238 (12%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
           + GQKGE G  G PG +      GI G  G  G +G +G  G +G  G +G+ GV G  G
Sbjct: 708 IQGQKGENGRQGIPGQQ------GIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMG 761

Query: 168 KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAM------------- 214
             G +G+PG  G +G  GL G  G++ S+      CT   +     +             
Sbjct: 762 PAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCL 821

Query: 215 ---GSPGLHGGP---GAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSK 268
              GSPG+ G P   G +G +G  G  G  G  G  G  G  G +G KG  G  GEKGS+
Sbjct: 822 SQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQ 881

Query: 269 GDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKG 326
           G  G  G+ G  G PG +G PGI  E    GPPG  G  G  GD G  G++G  G  G
Sbjct: 882 G-FGYPGEQGPPGPPGPEGPPGISKE----GPPGDPGLPGKDGDHGKPGIQGQPGPPG 934



 Score = 89.0 bits (219), Expect = 9e-18
 Identities = 53/135 (39%), Positives = 65/135 (48%), Gaps = 20/135 (14%)

Query: 102 CDCCSPVPGQKGEPGETGQPGPKGEAGNLGIP---GPPGVVGPQGPRGYKGEKGLKGERG 158
           CD C    G  G PG  G  GP+G  G  G+P   G PG+VG  G  G +G KGL G  G
Sbjct: 817 CDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNG 876

Query: 159 DQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPG 218
           ++G  G+ G PG QG PGP G +G  G+                  +G  GD G  G  G
Sbjct: 877 EKGSQGF-GYPGEQGPPGPPGPEGPPGIS----------------KEGPPGDPGLPGKDG 919

Query: 219 LHGGPGAKGEKGEMG 233
            HG PG +G+ G  G
Sbjct: 920 DHGKPGIQGQPGPPG 934



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 30/62 (48%), Positives = 35/62 (56%)

Query: 278 GRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGEL 337
           G+ GL G KGDPG+ G  G  G PG  G  G +G  G  GV G  G +G+RG  G KGE 
Sbjct: 449 GKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEP 508

Query: 338 AR 339
            R
Sbjct: 509 GR 510



 Score = 32.3 bits (72), Expect = 0.97
 Identities = 14/33 (42%), Positives = 20/33 (60%), Gaps = 6/33 (18%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGP 141
           PG  G+ G+ G+PG +G+      PGPPG+  P
Sbjct: 912 PGLPGKDGDHGKPGIQGQ------PGPPGICDP 938


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  205 bits (522), Expect = 6e-53
 Identities = 114/253 (45%), Positives = 132/253 (52%), Gaps = 18/253 (7%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
           PG++G PG+ G PGP G  G  G PG  GV GP GP G +G  G  G  G +G  G PG 
Sbjct: 658 PGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGA 717

Query: 169 PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGE 228
           PG+QG PG +G  G  G  G+ G KG +GD          G +GA GSPG  G  G  G 
Sbjct: 718 PGSQGAPGLQGMPGERGAAGLPGPKGDRGDA---------GPKGADGSPGKDGVRGLTGP 768

Query: 229 KGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGD 288
            G  G  G  GDKG  G SG  G  G +G  G +GE G  G +G  G  G +G PGAKG+
Sbjct: 769 IGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGE 828

Query: 289 PGIKGEKGELGPPGLLGPTGPKGDIGN------KGVRGPTGKKGSRGFKGSKGELARVPR 342
           PG  G KG+ GPPG  GP GP G IGN      KG RG  G  G+ GF G+ G   RV  
Sbjct: 829 PGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAG---RVGP 885

Query: 343 SAFSAGLSKPFPP 355
              S     P PP
Sbjct: 886 PGPSGNAGPPGPP 898



 Score =  192 bits (487), Expect = 7e-49
 Identities = 106/249 (42%), Positives = 125/249 (50%), Gaps = 8/249 (3%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG  G+PG  G+PG  G  G+ G PGP G  GP GP G  G  G KG RG  G PG  G 
Sbjct: 817  PGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGF 876

Query: 169  PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGE 228
            PGA G  GP G  GN G  G  G  G +G       KG +G+ G  G PG  G PG  G 
Sbjct: 877  PGAAGRVGPPGPSGNAGPPGPPGPAGKEGG------KGPRGETGPAGRPGEVGPPGPPGP 930

Query: 229  KGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGD 288
             GE G  G  G  G  G  G +G  GQ+G  G+ G++G +G  G+ G SG  G  G  G 
Sbjct: 931  AGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGA 990

Query: 289  PGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGEL--ARVPRSAFS 346
             G +G  G +GPPGL GP G  G  G  G  G  G+ GS G KG +GE   A  P +  +
Sbjct: 991  SGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGA 1050

Query: 347  AGLSKPFPP 355
             G   P  P
Sbjct: 1051 PGAPGPVGP 1059



 Score =  189 bits (481), Expect = 4e-48
 Identities = 113/273 (41%), Positives = 137/273 (50%), Gaps = 29/273 (10%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGY------------KGEKGLKGE 156
           PG+ G PGE G PG KG  G+ G PGP G  GP GP G             +G+ G+ G 
Sbjct: 523 PGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGF 582

Query: 157 RGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGS 216
            G +G  G PGK G +G PGP G  G  G  G  G +G  G        GE+G+QG  GS
Sbjct: 583 PGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPA---GPAGERGEQGPAGS 639

Query: 217 PGLHGGPGAKGEKGEMGEKGEM---GDKGCCGDSGERGGKGQKGEGGM---------KGE 264
           PG  G PG  G  GE G+ GE    GD G  G SG RG +G  GE G+         +G 
Sbjct: 640 PGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGA 699

Query: 265 KGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGK 324
            G+ G+ G +G +G  G PG++G PG++G  GE G  GL GP G +GD G KG  G  GK
Sbjct: 700 NGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGK 759

Query: 325 KGSRGFKGSKGE--LARVPRSAFSAGLSKPFPP 355
            G RG  G  G    A  P     +G S P  P
Sbjct: 760 DGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGP 792



 Score =  187 bits (476), Expect = 1e-47
 Identities = 111/268 (41%), Positives = 131/268 (48%), Gaps = 17/268 (6%)

Query: 109  PGQKGEPGETGQPGPKG---EAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGY 165
            PG KG  G  G PG  G    AG +G PGP G  GP GP G  G++G KG RG+ G  G 
Sbjct: 859  PGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGR 918

Query: 166  PGKPGAQGEPGPKGDKGNIGLG------------GVKGQKGSKGDTCGNCTKGEKGDQGA 213
            PG+ G  G PGP G+KG+ G              G+ GQ+G  G       +G  G  G 
Sbjct: 919  PGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGP 978

Query: 214  MGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGM 273
             G PG  G  GA GE+G  G  G  G  G  G+SG  G  G +G  G  G  G+KGD G 
Sbjct: 979  SGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGE 1038

Query: 274  EGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGS 333
             G +G  G PGA G PG  G  G+ G  G  GP GP G +G  G RGP G +G RG KG 
Sbjct: 1039 TGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGE 1098

Query: 334  KGELA--RVPRSAFSAGLSKPFPPPNIP 359
             GE     +      +GL  P  PP  P
Sbjct: 1099 TGEQGDRGIKGHRGFSGLQGPPGPPGSP 1126



 Score =  187 bits (475), Expect = 2e-47
 Identities = 107/255 (41%), Positives = 127/255 (49%), Gaps = 18/255 (7%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
           PG KG  GE G PG KG+ G  G PGP GV GP GP G +G++G +GE G  G+PG PG+
Sbjct: 427 PGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGE 486

Query: 169 ---------PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGL 219
                    PGA G  GPKG  G  G  G  G KGS G+       G  G+ G  G+ GL
Sbjct: 487 RGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEA------GRPGEAGLPGAKGL 540

Query: 220 HGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGR 279
            G PG+ G  G+ G  G  G  G  G  G  G +GQ G  G  G KG+ G+ G  G+ G 
Sbjct: 541 TGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGV 600

Query: 280 NGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELAR 339
            G PGA G  G  GE G  GPP   GP GP G+ G +G  G  G +G  G  G  GE  +
Sbjct: 601 PGPPGAVGPAGKDGEAGAQGPP---GPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGK 657

Query: 340 VPRSAFSAGLSKPFP 354
                    L  P P
Sbjct: 658 PGEQGVPGDLGAPGP 672



 Score =  187 bits (474), Expect = 2e-47
 Identities = 110/261 (42%), Positives = 132/261 (50%), Gaps = 15/261 (5%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
           PG  GE G  GQ GP+G  G  G PG PG  G +G  G  G  G  G  G  G PG+PG 
Sbjct: 289 PGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGA 348

Query: 169 PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDT-----CGN-CTKGEKGDQGAMGSPGLHGG 222
            GA+GE GP+G +G+ G  GV+G+ G  G        GN    G+ G +GA G+PG+ G 
Sbjct: 349 VGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGA 408

Query: 223 PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGE------KGSKGDSGMEGK 276
           PG  G +G  G +G  G  G  G+SGE G  G KG+ G KGE      +G  G +G EGK
Sbjct: 409 PGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGK 468

Query: 277 SGRNGLPGAKGDPGIKGEK---GELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGS 333
            G  G PG  G PG  GE+   G  G PG  G  GPKG  G +G  GP G KGS G  G 
Sbjct: 469 RGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGR 528

Query: 334 KGELARVPRSAFSAGLSKPFP 354
            GE         +     P P
Sbjct: 529 PGEAGLPGAKGLTGSPGSPGP 549



 Score =  183 bits (465), Expect = 3e-46
 Identities = 110/273 (40%), Positives = 132/273 (48%), Gaps = 31/273 (11%)

Query: 110 GQKGEPGETGQPGPKGE---AGNLGIPGPPGVVGPQGPRGYK------------------ 148
           G +GEPG TG PGP GE    G+ G PG  GV GP+GP G +                  
Sbjct: 470 GARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRP 529

Query: 149 GEKGLKGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEK 208
           GE GL G +G  G PG PG  G  G PGP G  G  G  G  G +G  G       KG  
Sbjct: 530 GEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAA 589

Query: 209 GDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSK 268
           G+ G  G  G+ G PGA G  G+ GE G  G  G  G +GERG +G  G  G +G  G  
Sbjct: 590 GEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPA 649

Query: 269 GDSGMEGKSGRNGLP---------GAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVR 319
           G  G  GK G  G+P         GA+G+ G  GE+G  GPPG  GP G  G  GN G +
Sbjct: 650 GPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAK 709

Query: 320 GPTGKKGSRGFKGSKGELARVPRSAFSAGLSKP 352
           G  G  G+ G +G+ G L  +P    +AGL  P
Sbjct: 710 GDAGAPGAPGSQGAPG-LQGMPGERGAAGLPGP 741



 Score =  183 bits (465), Expect = 3e-46
 Identities = 109/271 (40%), Positives = 131/271 (48%), Gaps = 20/271 (7%)

Query: 109  PGQKGEPGETGQPGP---KGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGY 165
            PG KGE G +G  GP   +G  G+ G PGPPG  G  GP G  G+ G KGE GD G  G 
Sbjct: 778  PGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGD 837

Query: 166  PGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKG--------DTCGNC-TKGEKGDQGAMGS 216
             G PG  G  GP G  GN+G  G KG +GS G           G     G  G+ G  G 
Sbjct: 838  AGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGP 897

Query: 217  PGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGK 276
            PG  G  G KG +GE G  G  G+ G  G  G  G KG  G  G  G  G+ G  G+ G+
Sbjct: 898  PGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQ 957

Query: 277  SGRNGLPGAKGD------PGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGF 330
             G  GLPG +G+      PG  GE G+ GP G  G  GP G +G  G+ GP G+ G  G 
Sbjct: 958  RGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGA 1017

Query: 331  KGSKGELAR--VPRSAFSAGLSKPFPPPNIP 359
             G++G   R   P +    G + P  PP  P
Sbjct: 1018 PGAEGSPGRDGSPGAKGDRGETGPAGPPGAP 1048



 Score =  183 bits (464), Expect = 3e-46
 Identities = 110/262 (41%), Positives = 130/262 (49%), Gaps = 18/262 (6%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
           PG  G  GE G  GP+G  G  G+ G PG  GP G  G  G  G  G+ G +G  G PG 
Sbjct: 346 PGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGI 405

Query: 169 PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGE 228
            GA G PG +G  G  G GG  G KG+ G+     +KG+ G +G  G  G+ G PG  GE
Sbjct: 406 AGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGE 465

Query: 229 KGEMGEKGEMGDKGCCGDSGERGGKGQK---------GEGGMKGEKGSKGDSGMEGKSGR 279
           +G+ G +GE G  G  G  GERGG G +         G  G  GE+GS G +G +G  G 
Sbjct: 466 EGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGE 525

Query: 280 NGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSR------GFKGS 333
            G PG  G PG KG  G  G PG  G TGP G  G  G  GP G  G+R      GF G 
Sbjct: 526 AGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGP 585

Query: 334 KGELARVPRSAFSAGLSKPFPP 355
           KG  A  P  A   G+  P PP
Sbjct: 586 KG-AAGEPGKAGERGV--PGPP 604



 Score =  183 bits (464), Expect = 3e-46
 Identities = 111/277 (40%), Positives = 135/277 (48%), Gaps = 37/277 (13%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGI---PGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYP 166
           G  G PG  GQPG KG  G  GI   PG PG  GP GP+G  G  G KG  G+ G PG  
Sbjct: 383 GPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSK 442

Query: 167 GKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAK 226
           G  GA+GEPGP G +G  G  G +G++G++G+       G  G++G  GS G  G  G  
Sbjct: 443 GDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVA 502

Query: 227 GEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGK------SGRN 280
           G KG  GE+G  G  G  G  GE G  G+ G  G KG  GS G  G +GK      +G++
Sbjct: 503 GPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQD 562

Query: 281 GLP---------------------GAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVR 319
           G P                     GA G+PG  GE+G  GPPG +GP G  G+ G +G  
Sbjct: 563 GRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPP 622

Query: 320 GPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPPP 356
           GP G  G RG +G  G       S    GL  P  PP
Sbjct: 623 GPAGPAGERGEQGPAG-------SPGFQGLPGPAGPP 652



 Score =  182 bits (462), Expect = 6e-46
 Identities = 98/231 (42%), Positives = 119/231 (51%), Gaps = 3/231 (1%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
           V G  G  GE G+ G +GE G  G+PGPPG  G  G RG+ G  G+ G +G  G  G PG
Sbjct: 456 VQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPG 515

Query: 168 KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKG 227
             G +G PG  G  G  GL G KG  GS G    +   G  G  G  G PG  G PGA+G
Sbjct: 516 PAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARG 575

Query: 228 EKGEM---GEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPG 284
           + G M   G KG  G+ G  G+ G  G  G  G  G  GE G++G  G  G +G  G  G
Sbjct: 576 QAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQG 635

Query: 285 AKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
             G PG +G  G  GPPG  G  G +G  G+ G  GP+G +G RGF G +G
Sbjct: 636 PAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERG 686



 Score =  181 bits (458), Expect = 2e-45
 Identities = 106/277 (38%), Positives = 125/277 (45%), Gaps = 34/277 (12%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGP------PGVVGPQGPRGYKGEKGLKGERGDQGVP 163
            G  G PGE G PGP G AG  G PG       PG  GPQG  G +G  GL G+RG++G P
Sbjct: 914  GPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFP 973

Query: 164  GYPGK------------------PGAQGEPG---PKGDKGNIGLGGVKGQKGSKGDTCGN 202
            G PG                   PG  G PG   P G+ G  G  G +G  G  G     
Sbjct: 974  GLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAK 1033

Query: 203  CTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMK 262
              +GE G  G  G+PG  G PG  G  G+ G++GE G  G  G  G  G +G  G  G +
Sbjct: 1034 GDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPR 1093

Query: 263  GEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPT 322
            G+KG  G+ G  G  G  G  G +G PG  G  GE GP G  GP GP+G  G+ G  G  
Sbjct: 1094 GDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKD 1153

Query: 323  GKKGSRGFKGSKGELARVPRSAFSAGLSKPFPPPNIP 359
            G  G  G  G  G   R        G + P  PP  P
Sbjct: 1154 GLNGLPGPIGPPGPRGR-------TGDAGPVGPPGPP 1183



 Score =  180 bits (456), Expect = 3e-45
 Identities = 99/242 (40%), Positives = 124/242 (51%), Gaps = 15/242 (6%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           G+ G+PG  G+ GP G  G  G+PG  G+ G +G RG+ G  G KG+ G  G  G PG P
Sbjct: 233 GEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSP 292

Query: 170 GAQGEP---GPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAK 226
           G  G P   GP+G  G  G  G  G  G++G+       G  G  G  G PG  G  GAK
Sbjct: 293 GENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAK 352

Query: 227 GEKGEMGEKGEMGDKGCCGD---SGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLP 283
           GE G  G +G  G +G  G+    G  G  G  G  G  G+ G+KG +G  G +G  G P
Sbjct: 353 GEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFP 412

Query: 284 GAK---------GDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSK 334
           GA+         G PG KG  GE G PG  G TG KG+ G  GV+GP G  G  G +G++
Sbjct: 413 GARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGAR 472

Query: 335 GE 336
           GE
Sbjct: 473 GE 474



 Score =  177 bits (449), Expect = 2e-44
 Identities = 101/247 (40%), Positives = 121/247 (48%), Gaps = 4/247 (1%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           G +G PG  G PGP+G  G  G PG PG  GP GPR   G  G  G+ GD G  G PG+P
Sbjct: 185 GPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPR---GPPGPPGKNGDDGEAGKPGRP 241

Query: 170 GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
           G +G PGP+G +G  G  G+ G KG +G +  +  KG+ G  G  G PG  G  GA G+ 
Sbjct: 242 GERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQM 301

Query: 230 GEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDP 289
           G  G  GE G  G  G +G RG  G  G  G  G  G  G  G  G  G  G  G +G  
Sbjct: 302 GPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPR 361

Query: 290 GIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGL 349
           G +G +G  G PG  GP G  G  GN G  G  G KG+ G  G  G     P +   +G 
Sbjct: 362 GSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAG-APGFPGARGPSGP 420

Query: 350 SKPFPPP 356
             P  PP
Sbjct: 421 QGPGGPP 427



 Score =  176 bits (447), Expect = 3e-44
 Identities = 99/231 (42%), Positives = 118/231 (51%), Gaps = 6/231 (2%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGL---KGERGDQGVPG 164
            +PGQ+GE G  G PGP GE G     GP G  G +GP G  G  GL    GE G +G PG
Sbjct: 963  LPGQRGERGFPGLPGPSGEPGK---QGPSGASGERGPPGPMGPPGLAGPPGESGREGAPG 1019

Query: 165  YPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPG 224
              G PG  G PG KGD+G  G  G  G  G+ G        G+ GD+G  G  G  G  G
Sbjct: 1020 AEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVG 1079

Query: 225  AKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPG 284
              G +G  G +G  GDKG  G+ G+RG KG +G  G++G  G  G  G +G SG +G  G
Sbjct: 1080 PVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAG 1139

Query: 285  AKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
             +G PG  G  G+ G  GL GP GP G  G  G  GP G  G  G  G  G
Sbjct: 1140 PRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPG 1190



 Score =  174 bits (441), Expect = 2e-43
 Identities = 101/260 (38%), Positives = 123/260 (47%), Gaps = 12/260 (4%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
           +PG KG+ G+ G  G  G  G  G+ G  G +GP GP G  G+KG  G  G  G  G  G
Sbjct: 738 LPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARG 797

Query: 168 KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLH------G 221
            PG +GEPGP G  G  G  G  GQ G+KG+      KG+ G  G  G  G        G
Sbjct: 798 APGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVG 857

Query: 222 GPGAKGEKGEMGEKGEMGDKGCC------GDSGERGGKGQKGEGGMKGEKGSKGDSGMEG 275
            PGAKG +G  G  G  G  G        G SG  G  G  G  G +G KG +G++G  G
Sbjct: 858 APGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAG 917

Query: 276 KSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
           + G  G PG  G  G KG  G  GP G  G  GP+G  G +GV G  G++G RGF G  G
Sbjct: 918 RPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPG 977

Query: 336 ELARVPRSAFSAGLSKPFPP 355
                 +   S    +  PP
Sbjct: 978 PSGEPGKQGPSGASGERGPP 997



 Score =  173 bits (439), Expect = 3e-43
 Identities = 106/261 (40%), Positives = 123/261 (47%), Gaps = 22/261 (8%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQG---------PRGYKGEKGLKGERGDQ 160
           GQ G PG  G PG +G+AG +G PGP G  G  G         P G  G  G  GE G Q
Sbjct: 560 GQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQ 619

Query: 161 GVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLH 220
           G PG  G  G +GE GP G  G  GL G  G  G  G       +G  GD GA G  G  
Sbjct: 620 GPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKP---GEQGVPGDLGAPGPSGAR 676

Query: 221 GGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRN 280
           G  G  GE+G  G  G  G +G  G  G  G KG  G  G  G +G+ G  GM G+ G  
Sbjct: 677 GERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAA 736

Query: 281 GLPGAKGDPGIKGEKGELGPPGL---------LGPTGPKGDIGNKGVRGPTGKKGSRGFK 331
           GLPG KGD G  G KG  G PG          +GP GP G  G+KG  GP+G  G  G +
Sbjct: 737 GLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGAR 796

Query: 332 GSKGELARVPRSAFSAGLSKP 352
           G+ G+    P     AG + P
Sbjct: 797 GAPGDRGE-PGPPGPAGFAGP 816



 Score =  173 bits (438), Expect = 4e-43
 Identities = 102/240 (42%), Positives = 118/240 (49%), Gaps = 12/240 (5%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
           +PG KG  G +G  G KG+AG  G  G PG  G  G  G  G +GL GERG  G PG  G
Sbjct: 261 LPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAG 320

Query: 168 ---KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPG 224
                GA G  GP G  G  G  G  G  G+KG+      +G +G QG  G PG  G  G
Sbjct: 321 ARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAG 380

Query: 225 AKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPG 284
           A G  G  G  G+ G KG  G  G  G  G  G  G  G +G  G  G +G SG  G PG
Sbjct: 381 AAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPG 440

Query: 285 AKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKG---------SRGFKGSKG 335
           +KGD G KGE G +G  G  GP G +G  G +G  GPTG  G         SRGF G+ G
Sbjct: 441 SKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADG 500



 Score =  172 bits (436), Expect = 6e-43
 Identities = 105/271 (38%), Positives = 129/271 (47%), Gaps = 31/271 (11%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQ---------------GPRGYKGEKGLK 154
            G++G  G  G+ GP G  G +G PGPPG  G +               GP+G  G++G+ 
Sbjct: 902  GKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVV 961

Query: 155  GERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAM 214
            G  G +G  G+PG PG  GEPG +G  G  G  G  G  G  G        G +G  GA 
Sbjct: 962  GLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAE 1021

Query: 215  GSPGLHGGPGAKGEKGEMGEKGEMGDKGC---------CGDSGERGGKGQKGEGGMKGEK 265
            GSPG  G PGAKG++GE G  G  G  G           G SG+RG  G  G  G  G  
Sbjct: 1022 GSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPV 1081

Query: 266  GSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKK 325
            G++G +G +G  G  G  G +GD GIKG +G     GL GP GP G  G +G  G +G  
Sbjct: 1082 GARGPAGPQGPRGDKGETGEQGDRGIKGHRGF---SGLQGPPGPPGSPGEQGPSGASGPA 1138

Query: 326  GSRGFKGSKGELARVPRSAFSAGLSKPFPPP 356
            G RG  GS G     P      GL  P  PP
Sbjct: 1139 GPRGPPGSAG----APGKDGLNGLPGPIGPP 1165



 Score =  171 bits (432), Expect = 2e-42
 Identities = 97/241 (40%), Positives = 114/241 (47%), Gaps = 15/241 (6%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           G +G PG  G PG KG  G  G+ G  G  GP GP+G  G  G  G  G  G  G PG+ 
Sbjct: 251 GARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGER 310

Query: 170 GAQGEPGPKGDKGNIGLGGVKGQK---------------GSKGDTCGNCTKGEKGDQGAM 214
           G  G PGP G +GN G  G  G                 G+KG+      +G +G QG  
Sbjct: 311 GRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVR 370

Query: 215 GSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGME 274
           G PG  G  GA G  G  G  G+ G KG  G  G  G  G  G  G  G +G  G  G +
Sbjct: 371 GEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPK 430

Query: 275 GKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSK 334
           G SG  G PG+KGD G KGE G +G  G  GP G +G  G +G  GPTG  G  G +G  
Sbjct: 431 GNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGP 490

Query: 335 G 335
           G
Sbjct: 491 G 491



 Score =  170 bits (430), Expect = 3e-42
 Identities = 99/238 (41%), Positives = 119/238 (50%), Gaps = 12/238 (5%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           G KG+ G  G PG +G  G  G+PG  G  G  GP+G +G+ G KG  G  G  G  G  
Sbjct: 707 GAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLT 766

Query: 170 GAQGEPGP---KGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAK 226
           G  G PGP    GDKG  G  G  G  G++G        G  G  G  G PG  G PGAK
Sbjct: 767 GPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAK 826

Query: 227 GEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGD---SGMEGKSGRNGLP 283
           GE G+ G KG+ G  G  G +G  G  G  G  G KG +GS G    +G  G +GR G P
Sbjct: 827 GEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPP 886

Query: 284 GAKGD------PGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
           G  G+      PG  G++G  GP G  GP G  G++G  G  GP G+KGS G  G  G
Sbjct: 887 GPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAG 944



 Score =  169 bits (429), Expect = 4e-42
 Identities = 108/285 (37%), Positives = 127/285 (44%), Gaps = 52/285 (18%)

Query: 101 CCDCCSPVPGQKGEPGETGQPGPKGEA------------GNLGIPGPPGVVGPQGPRGYK 148
           CC  C        +   TG  GPKG+             G  GIPG PG+ GP GP G  
Sbjct: 91  CCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPP 150

Query: 149 GEKGL-------------------------KGERGDQGVPGYPGKPGAQGEPGPKGDKGN 183
           G  GL                          G  G +G+PG PG PG QG  GP G+ G 
Sbjct: 151 GPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGE 210

Query: 184 IGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGC 243
            G  G  G +G  G    N   G+ G+ G  G PG  G PG +G +G  G  G  G KG 
Sbjct: 211 PGASGPMGPRGPPGPPGKN---GDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGH 267

Query: 244 CGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGI---------KGE 294
            G SG  G KG  G  G KGE GS G++G  G+ G  GLPG +G PG           G 
Sbjct: 268 RGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGA 327

Query: 295 KGELGPPGLLGPTGP---KGDIGNKGVRGPTGKKGSRGFKGSKGE 336
            G  GPPG  GP GP    G +G KG  GP G +GS G +G +GE
Sbjct: 328 TGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGE 372



 Score =  129 bits (325), Expect = 4e-30
 Identities = 76/193 (39%), Positives = 86/193 (44%), Gaps = 18/193 (9%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG +G PG  G PG KG+ G  G  GPPG  G  G  G  G  G  G+RG+         
Sbjct: 1018 PGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGE--------- 1068

Query: 169  PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGE 228
                G  GP G  G +G  G  G +G +GD      KGE G+QG  G  G  G  G +G 
Sbjct: 1069 ---TGPAGPAGPVGPVGARGPAGPQGPRGD------KGETGEQGDRGIKGHRGFSGLQGP 1119

Query: 229  KGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGD 288
             G  G  GE G  G  G +G RG  G  G  G  G  G  G  G  G  GR G  G  G 
Sbjct: 1120 PGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGP 1179

Query: 289  PGIKGEKGELGPP 301
            PG  G  G  GPP
Sbjct: 1180 PGPPGPPGPPGPP 1192



 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 33/78 (42%), Positives = 37/78 (47%), Gaps = 6/78 (7%)

Query: 106  SPVPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYK------GEKGLKGERGD 159
            S + G  G PG  G+ GP G +G  G  GPPG  G  G  G        G  G +G  GD
Sbjct: 1114 SGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGD 1173

Query: 160  QGVPGYPGKPGAQGEPGP 177
             G  G PG PG  G PGP
Sbjct: 1174 AGPVGPPGPPGPPGPPGP 1191



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 34/90 (37%), Positives = 44/90 (48%), Gaps = 16/90 (17%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLG---------IPGPPGVVGPQGPRGYKGEKGLKGERGD 159
            PG++G  G +G  GP+G  G+ G         +PGP    GP GPRG  G+ G  G  G 
Sbjct: 1126 PGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPI---GPPGPRGRTGDAGPVGPPGP 1182

Query: 160  QGVPGYPGKPGAQGE----PGPKGDKGNIG 185
             G PG PG P A  +    P P  +K + G
Sbjct: 1183 PGPPGPPGPPSAGFDFSFLPQPPQEKAHDG 1212



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 27/74 (36%), Positives = 34/74 (45%), Gaps = 8/74 (10%)

Query: 287 GDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAF- 345
           G  G KG+ G  GP G  GP G  G  G  G+ GP G  G  G  G  G  A  P+ ++ 
Sbjct: 109 GVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFA--PQLSYG 166

Query: 346 -----SAGLSKPFP 354
                + G+S P P
Sbjct: 167 YDEKSTGGISVPGP 180



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 18/39 (46%), Positives = 21/39 (53%)

Query: 103  DCCSPVPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGP 141
            D  + +PG  G PG  G+ G  G  G  G PGPPG  GP
Sbjct: 1153 DGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGP 1191


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  199 bits (505), Expect = 6e-51
 Identities = 122/292 (41%), Positives = 148/292 (50%), Gaps = 27/292 (9%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
            G+KGEPGE G PGP GEAG  G  G  G  G  GP G  G  G KG  GD G  G PG  
Sbjct: 1264 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1323

Query: 170  GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
            G  G+PGP G+ G  G  GV G KG  GD       G  G+ G  G PG  G PGA G +
Sbjct: 1324 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1383

Query: 230  GEMGEKGEMGDKGC------CGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRN--- 280
            G  GEKG  G+ G        G  G +G  G+ G  G++G  G  G+ G+ G +G++   
Sbjct: 1384 GRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1443

Query: 281  ------GLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSK 334
                  GLPG KGDPG KGEKG    PGL+G  GP G+ G KG RG  G +GS G KG  
Sbjct: 1444 GPMGPPGLPGLKGDPGSKGEKGH---PGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG 1500

Query: 335  GELARVPRSAFSAGLSKPFPPPNIPIKFEKILYNDQGNYSPVTGKFNCSIPG 386
            G    +P  A   G   P  PP +P    +    ++G+  P   K +  +PG
Sbjct: 1501 G----IPGPAGPLG---PPGPPGLP--GPQGPKGNKGSTGPAGQKGDSGLPG 1543



 Score =  197 bits (500), Expect = 2e-50
 Identities = 107/234 (45%), Positives = 130/234 (55%), Gaps = 6/234 (2%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGP------RGYKGEKGLKGERGDQGV 162
           PG  G  GE+G PGP+G  G  G PGP G  G +G       RG  GE G KG+RG  G+
Sbjct: 558 PGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGL 617

Query: 163 PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
           PG PG  G +GE GP+G  G  G  G++G+ G  G        G +G  G  G+PG  G 
Sbjct: 618 PGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQ 677

Query: 223 PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGL 282
           PG  G  G  G KG MG +G  G  G++G  G +G  G +G  G  G+ G +GK G  GL
Sbjct: 678 PGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGL 737

Query: 283 PGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
           PGA G PG  G++G+ G  G LGP GP+G IG  G RG  G  G RG KGSKGE
Sbjct: 738 PGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 791



 Score =  195 bits (495), Expect = 9e-50
 Identities = 108/245 (44%), Positives = 133/245 (54%), Gaps = 27/245 (11%)

Query: 109 PGQKGEPGETGQPGPKGEAGN---LGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGY 165
           PG KG  G  G+PGP G+ GN    G+PGP G +GP G +G +G+ GL G  G  G PG+
Sbjct: 687 PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 746

Query: 166 PGKPGAQGE------PGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGL 219
           PGK G  GE      PGP+G  G  G  GVKG  G +G       KG KG++G  G PG 
Sbjct: 747 PGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRG------LKGSKGEKGEDGFPGF 800

Query: 220 HGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGR 279
            G  G KG++GE+G+ G  G+ G  G  G  G  G  G  G  GEKG  G  G+ G  GR
Sbjct: 801 KGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGR 860

Query: 280 N---------GLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGF 330
                     G PGA G+ G +G  G+ GP G  GPTGP+   G++G RGPTGK G +G 
Sbjct: 861 QGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPR---GSRGARGPTGKPGPKGT 917

Query: 331 KGSKG 335
            G  G
Sbjct: 918 SGGDG 922



 Score =  193 bits (490), Expect = 3e-49
 Identities = 103/234 (44%), Positives = 131/234 (55%), Gaps = 6/234 (2%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
           +PG KG  GE G  GP G  G+ G+ G  G +GP+G  G  G +GL G RG  G PG PG
Sbjct: 620 LPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPG 679

Query: 168 KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGD---TCGNCTKGEKGDQGAMGSPGLHGGPG 224
             G  G PGPKG+ G  G  G  GQ+G+ G           G  G++G  G PGL G PG
Sbjct: 680 MAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPG 739

Query: 225 AKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPG 284
           A G  G  G++G+ G+KG  G  G +G  G  G  G+KG  G +G  G +G+ G +G PG
Sbjct: 740 ADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG 799

Query: 285 AKGDPGIKGEKGE---LGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
            KGD G+KG++GE   +GP G  GP GPKG  G  G  GP+G+ G +G  G  G
Sbjct: 800 FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG 853



 Score =  190 bits (483), Expect = 2e-48
 Identities = 99/237 (41%), Positives = 134/237 (56%), Gaps = 9/237 (3%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
           +PG  G PG  G+ G  GE G LG PGP G +G  GPRG KG  G++G +G +G  G  G
Sbjct: 737 LPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDG 796

Query: 168 KPGAQGEPGPKGDKGNIGLGGVKGQ------KGSKGDTCGNCTKGEKGDQGAMGSPGLHG 221
            PG +G+ G KGD+G +G  G +G+      KG  G T      G+ G++G +G PGL G
Sbjct: 797 FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG 856

Query: 222 GPGAKGEKGEM---GEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSG 278
            PG +G KG     G  G  G+KG  G +G+ G +GQ+G  G +G +G++G +G  G  G
Sbjct: 857 YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 916

Query: 279 RNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
            +G  G  G PG +G +G  GP G  GP GP G  G  G+ G  G++G  GF+G  G
Sbjct: 917 TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 973



 Score =  190 bits (482), Expect = 3e-48
 Identities = 112/253 (44%), Positives = 127/253 (50%), Gaps = 27/253 (10%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGP------------QGPRGYKGEKGLKGER 157
            G KGE GE GQ G KG+ G  G PGPPG+ GP             GPRG +G  G KG+ 
Sbjct: 1138 GDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDE 1197

Query: 158  GDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSP 217
            G +G PG PG  G QG PGP G+KG  G  G  G  G  G        G  G QG  GS 
Sbjct: 1198 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV 1257

Query: 218  GLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKS 277
            G  GG G KGE GE G  G  G+ G  G  GERG KG+ G  G  G  G+KG  G +G  
Sbjct: 1258 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK 1317

Query: 278  GRNGLPGAKGDP------------GIKGEKGELGPPGLLGPTGPKGDI---GNKGVRGPT 322
            G  G  G  GDP            G+ G+KGE G PG  GP GP G+    G  G RGP 
Sbjct: 1318 GNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPP 1377

Query: 323  GKKGSRGFKGSKG 335
            G  G+ G +G KG
Sbjct: 1378 GAAGAEGRQGEKG 1390



 Score =  190 bits (482), Expect = 3e-48
 Identities = 108/248 (43%), Positives = 122/248 (49%), Gaps = 21/248 (8%)

Query: 109  PGQKGEPGETGQPG---PKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGY 165
            PG  G PG  G PG   PKG  G +G PG PG  G  GP G  G  G KGE GD G PG 
Sbjct: 1299 PGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGP 1358

Query: 166  PGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGA 225
            PG  G  G PGP G +G  G  G +G++G KG       +G  G  G +G  G  G PG 
Sbjct: 1359 PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1418

Query: 226  KGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGM------------ 273
            +G +G  G  GE G  G  G  G  G  G  G  G+KG+ GSKG+ G             
Sbjct: 1419 EGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGE 1478

Query: 274  ------EGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGS 327
                   G  G  G PGAKGD GI G  G LGPPG  G  GP+G  GNKG  GP G+KG 
Sbjct: 1479 QGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGD 1538

Query: 328  RGFKGSKG 335
             G  G  G
Sbjct: 1539 SGLPGPPG 1546



 Score =  189 bits (481), Expect = 4e-48
 Identities = 108/254 (42%), Positives = 127/254 (50%), Gaps = 33/254 (12%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG+ G PG  GQ G  G  G  G PGP GVVGPQGP G  G  G +G  G  G PG  G 
Sbjct: 951  PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGL 1010

Query: 169  PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGE 228
            PGA G+ G KGD G  G+ G  G  G +G        GE+G  GA G+PGL GG G +G 
Sbjct: 1011 PGAAGKEGAKGDPGPQGISGKDGPAGLRG------FPGERGLPGAQGAPGLKGGEGPQGP 1064

Query: 229  KGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGL------ 282
             G +G  GE G  G  G  G  G  G +G  G  GEKG+ G+ G +G +GR+G+      
Sbjct: 1065 PGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGL 1124

Query: 283  ---------------------PGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGP 321
                                 PG KG  G KGE G  GPPGL GP G  G  G  G  GP
Sbjct: 1125 PGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGP 1184

Query: 322  TGKKGSRGFKGSKG 335
             G++G  G KG +G
Sbjct: 1185 RGQQGMFGQKGDEG 1198



 Score =  188 bits (478), Expect = 8e-48
 Identities = 106/240 (44%), Positives = 125/240 (52%), Gaps = 12/240 (5%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG  GE G  G+ GP+G AG  G+ GP G+ GP GP G  GE G KGE G+ G  G  G 
Sbjct: 1095 PGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGD 1154

Query: 169  PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSP------GLHGG 222
             G  G PGP G +G +G  G+ G  G  G        G+KGD+GA G P      GL G 
Sbjct: 1155 KGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGL 1214

Query: 223  PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGL 282
            PG  GEKGE G+ G MG  G  G  G +G  G  G  G  G  GS G  G +G+ G  G 
Sbjct: 1215 PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGN 1274

Query: 283  PGAKGDPGI------KGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
            PG  G+ G+      +GEKGE GPPG  GP G KG  G+ G +G  G  G  G  G  GE
Sbjct: 1275 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1334



 Score =  188 bits (477), Expect = 1e-47
 Identities = 112/270 (41%), Positives = 135/270 (50%), Gaps = 42/270 (15%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGP---RGYKGEK---------GLKGE 156
            PG  G PGE G PG  G+ G  G PGP G+ G  GP   RG+ GE+         GLKG 
Sbjct: 999  PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1058

Query: 157  RGDQGVP------------------GYPGKPGAQGEPGPKGDK---------GNIGLGGV 189
             G QG P                  G PG+PG QG PGP G+K         G  G  GV
Sbjct: 1059 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGV 1118

Query: 190  KGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGE---KGEMGDKGCCGD 246
            +G  G  G      + GE GD+G +G PG  G  G KGE G  G    +G +G  G  G 
Sbjct: 1119 QGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG 1178

Query: 247  SGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGP 306
             GE G +GQ+G  G KG++G++G  G  G  G  GLPG  G+ G  G+ G +GPPG  GP
Sbjct: 1179 DGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGP 1238

Query: 307  TGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
             GP+G  G  G +GP G  GS G  G KGE
Sbjct: 1239 RGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1268



 Score =  187 bits (475), Expect = 2e-47
 Identities = 115/262 (43%), Positives = 135/262 (51%), Gaps = 24/262 (9%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGL---KGERGDQGVPGY 165
           PGQ G  G  G PGPKG  G  G PGPPG  G  GP+G  G +G     GE+G QG PG 
Sbjct: 675 PGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGL 734

Query: 166 PGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGA 225
            G PGA G PG  G +G  G  G  G  G +G        G  G +G  G+ G+ G  G+
Sbjct: 735 AGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPI------GYPGPRGVKGADGVRGLKGS 788

Query: 226 KGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEK------GSKGDSGMEGKSGR 279
           KGEKGE G  G  GD G  GD GE G  G +GE G +G K      G  G SG  G+ G+
Sbjct: 789 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 848

Query: 280 NGLPGAKGDPGIKGEKGELGPPGLLGPTGPK------GDIGNKGVRGPTGKKGSRGFKGS 333
            G+PG  G PG +G KG  G PG  G  G K      G  G +G RGPTG +GSRG +G 
Sbjct: 849 LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 908

Query: 334 KGELARVPRSAFSAGLSKPFPP 355
            G+    P+   S G   P PP
Sbjct: 909 TGKPG--PKGT-SGGDGPPGPP 927



 Score =  186 bits (473), Expect = 3e-47
 Identities = 114/257 (44%), Positives = 128/257 (49%), Gaps = 33/257 (12%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPG----- 164
            G +G PG  G PG +G AG  G  G PG  GPQGP G  GEKG  GE+G QG  G     
Sbjct: 1060 GPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQ 1119

Query: 165  ----YPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLH 220
                 PG  G  G PG  GDKG IG     GQKGSKGD   N   G  G QG +G+PG+ 
Sbjct: 1120 GPVGLPGPAGPAGSPGEDGDKGEIG---EPGQKGSKGDKGENGPPGPPGLQGPVGAPGIA 1176

Query: 221  GGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGD---------S 271
            GG G  G +G+ G  G+ GD+G  G  G  G  G +G  G  GEKG  GD          
Sbjct: 1177 GGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPP 1236

Query: 272  GMEGKSGRNGLPGAKGDPGI---------KGEKGEL---GPPGLLGPTGPKGDIGNKGVR 319
            G  G  G NG  G +G PG          KGE GE    GPPG  G  GPKG+ G KG  
Sbjct: 1237 GPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEA 1296

Query: 320  GPTGKKGSRGFKGSKGE 336
            GP G  G  G KG  G+
Sbjct: 1297 GPPGAAGPPGAKGPPGD 1313



 Score =  185 bits (470), Expect = 7e-47
 Identities = 113/268 (42%), Positives = 134/268 (50%), Gaps = 25/268 (9%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGV------VGPQGPRGYKGEKGLKGERGDQGVP 163
            GQKG+ G  G PGP G  G  G+PGPPG       VGP GP G  G +G +G  G  G  
Sbjct: 1192 GQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1251

Query: 164  GYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGP 223
            G PG  G+ G  G KG+ G  G  G  G+ G  G       KGE+G++G  G PG  G P
Sbjct: 1252 GPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGG------PKGERGEKGEAGPPGAAGPP 1305

Query: 224  GAKGEKGEMGEKGEMGDKGCCGD---SGERGGKGQKGEGGMKGEKGS---------KGDS 271
            GAKG  G+ G KG  G  G  GD    GE G  GQ G GG KGE G           G++
Sbjct: 1306 GAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEA 1365

Query: 272  GMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFK 331
            G  G  G+ G PGA G  G +GEKG  G  G  GP G  G +G +G  G  G +G RG  
Sbjct: 1366 GPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIP 1425

Query: 332  GSKGELARVPRSAFSAGLSKPFPPPNIP 359
            G  GE   +P +A   G   P  PP +P
Sbjct: 1426 GPVGEQG-LPGAAGQDGPPGPMGPPGLP 1452



 Score =  184 bits (467), Expect = 2e-46
 Identities = 102/226 (45%), Positives = 123/226 (54%), Gaps = 3/226 (1%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
            G +G  G TG+PGPKG +G  G PGPPG  GPQGP+G  G  G KG  G  G  G PG P
Sbjct: 901  GSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHP 960

Query: 170  GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
            G +GE G +G  G  G GGV G +G  G+T      GE+G  G  G PG  G PGA G++
Sbjct: 961  GQRGETGFQGKTGPPGPGGVVGPQGPTGET---GPIGERGHPGPPGPPGEQGLPGAAGKE 1017

Query: 230  GEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDP 289
            G  G+ G  G  G  G +G RG  G++G  G +G  G KG  G +G  G  G PG +G  
Sbjct: 1018 GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA 1077

Query: 290  GIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
            G  G  G  G PG  GP GP G+ G  G +GP G  G  G +G  G
Sbjct: 1078 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG 1123



 Score =  182 bits (462), Expect = 6e-46
 Identities = 105/264 (39%), Positives = 137/264 (51%), Gaps = 14/264 (5%)

Query: 110  GQKGEPGETGQPGPKGEAGN---LGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYP 166
            G KG  G TG PGP G+AG    LG+PG PG  G QGP+G  G  G  G  G++G  G  
Sbjct: 826  GPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA 885

Query: 167  GKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAK 226
            GKPG +G+ GP G +G+ G  G  G+ G KG + G+   G  G++G  G  G  G PG K
Sbjct: 886  GKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPK 945

Query: 227  GEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAK 286
            G  G  G+ G  G  G  G++G +G  G  G GG+ G +G  G++G  G+ G  G PG  
Sbjct: 946  GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 1005

Query: 287  GDPGI------KGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGEL--- 337
            G+ G+      +G KG+ GP G+ G  GP G  G  G RG  G +G+ G KG +G     
Sbjct: 1006 GEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPP 1065

Query: 338  --ARVPRSAFSAGLSKPFPPPNIP 359
                 P    SAG + P   P  P
Sbjct: 1066 GPVGSPGERGSAGTAGPIGLPGRP 1089



 Score =  178 bits (452), Expect = 8e-45
 Identities = 102/249 (40%), Positives = 119/249 (47%), Gaps = 24/249 (9%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG KG  G  G PGP GE G  G  GP G  GP+GP G  G+ GL G  G +G  G+ GK
Sbjct: 912  PGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGK 971

Query: 169  P---------------------GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGE 207
                                  G +G PGP G  G  GL G  G++G+KGD       G+
Sbjct: 972  TGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 1031

Query: 208  KGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGS 267
             G  G  G PG  G PGA+G  G  G +G  G  G  G  GERG  G  G  G+ G  G 
Sbjct: 1032 DGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP 1091

Query: 268  KGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGS 327
            +G     G +G  G PG KG  G  G  G  GP GL GP GP G  G  G +G  G+ G 
Sbjct: 1092 QGP---PGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ 1148

Query: 328  RGFKGSKGE 336
            +G KG KGE
Sbjct: 1149 KGSKGDKGE 1157



 Score =  174 bits (440), Expect = 2e-43
 Identities = 111/284 (39%), Positives = 135/284 (47%), Gaps = 29/284 (10%)

Query: 110 GQKGEPG--ETGQ--PGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGY 165
           GQKGEP   E G    GP G AG  GI GPPG+ GP GP          G+ GD+G PG 
Sbjct: 438 GQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGP---------PGDPGDRGPPGR 488

Query: 166 PGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGN--------------CTKGEKGDQ 211
           PG PGA G PGP G    + L    G  GSKG T                   +G  G  
Sbjct: 489 PGLPGADGLPGPPGTM--LMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPM 546

Query: 212 GAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDS 271
           G  G PG  GGPG+ G KGE G+ G  G +G  G  G  G  G++G  G  G +G  G+ 
Sbjct: 547 GLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEP 606

Query: 272 GMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFK 331
           G +G  G +GLPG  GD G +GE+G  GPPG  G  G +G+ G  G RG  G+ G RG  
Sbjct: 607 GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 666

Query: 332 GSKGELARVPRSAFSAGLSKPFPPPNIPIKFEKILYNDQGNYSP 375
           G +G      +   +     P P  N+  + E      QGN  P
Sbjct: 667 GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 710



 Score =  169 bits (429), Expect = 4e-42
 Identities = 98/239 (41%), Positives = 126/239 (52%), Gaps = 21/239 (8%)

Query: 110  GQKGEPGETGQPG------PKGEAGNLGIPGPPGVVGPQGPRGYKG---EKGLKGERGDQ 160
            G KGE GE G PG       KG+ G +G  GP G  GP+GP+G  G   + G  G+ G++
Sbjct: 787  GSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEK 846

Query: 161  GVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLH 220
            G  G PG PG  G  GPKG  G  G  G  G+KG++G        G+ G +G  G  G  
Sbjct: 847  GKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARG------VAGKPGPRGQRGPTGPR 900

Query: 221  GGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRN 280
            G  GA+G  G+ G KG  G  G  G  GERG +G +G  G  G KG  G     GK G  
Sbjct: 901  GSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGP---PGKDGLP 957

Query: 281  GLPGAKGDPGIKGEKGELGPPGLLGPTGPKGD---IGNKGVRGPTGKKGSRGFKGSKGE 336
            G PG +G+ G +G+ G  GP G++GP GP G+   IG +G  GP G  G +G  G+ G+
Sbjct: 958  GHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 1016



 Score =  169 bits (428), Expect = 5e-42
 Identities = 106/263 (40%), Positives = 128/263 (48%), Gaps = 13/263 (4%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVG------PQGPRGYKGEKGLKGERGDQGV 162
           PG  G  G  G+PG KG+ G  G+PG PG  G      PQGP G  G+ G++GE G+ G 
Sbjct: 594 PGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP 653

Query: 163 PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
            G PG+ G +G  GP+G  G  G  G+ G  G  G       +GE G  G  G+PG  G 
Sbjct: 654 RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 713

Query: 223 PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGK---SGR 279
           PG +G  G  GEKG  G  G  G  G  G  G  G+ G  GEKG+ G  G +G     G 
Sbjct: 714 PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGP 773

Query: 280 NGLPGAKGDPGIKGEKGELGP---PGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
            G+ GA G  G+KG KGE G    PG  G  G KGD G  G  GP G+ G  G KG  G 
Sbjct: 774 RGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP 833

Query: 337 LARVPRSAFSAGLSKPFPPPNIP 359
               P  +  AG       P +P
Sbjct: 834 TGD-PGPSGQAGEKGKLGVPGLP 855



 Score =  168 bits (426), Expect = 9e-42
 Identities = 99/245 (40%), Positives = 125/245 (51%), Gaps = 21/245 (8%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           G  G  G TG+PGP G  G+ G  G  G  GPQGPRG +G  G  G+ G +G PG  G  
Sbjct: 541 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 600

Query: 170 GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
           G  GEPG KGD+G  GL G+ G KG +G         E+G QG          PG  G+ 
Sbjct: 601 GMPGEPGAKGDRGFDGLPGLPGDKGHRG---------ERGPQGP---------PGPPGDD 642

Query: 230 GEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDP 289
           G  GE GE+G +G  G++G RG  G +G  G  G+ G    +G++G  G  G  G +G+P
Sbjct: 643 GMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM---AGVDGPPGPKGNMGPQGEP 699

Query: 290 GIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGL 349
           G  G++G  GP GL GP GP G  G KG +G  G  G  G  G  G   +  +S     L
Sbjct: 700 GPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL 759

Query: 350 SKPFP 354
             P P
Sbjct: 760 GPPGP 764



 Score =  166 bits (421), Expect = 3e-41
 Identities = 101/264 (38%), Positives = 127/264 (48%), Gaps = 32/264 (12%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVV----------GPQGP--------------- 144
           G  G+PG+ G PG  G  G  G+PGPPG +          G +GP               
Sbjct: 475 GPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQ 534

Query: 145 -----RGYKGEKGLKGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDT 199
                RG  G  GL G  G  G PG  G  G  G+PGP+G +G  G  G  G+ G +G  
Sbjct: 535 ARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRP 594

Query: 200 CGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEG 259
             +  +G  G+ GA G  G  G PG  G+KG  GE+G  G  G  GD G RG  G+ G  
Sbjct: 595 GADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPR 654

Query: 260 GMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVR 319
           G+ GE G +G  G  G  G  G PG  G  G  G KG +GP G  GP G +G+ G +G+ 
Sbjct: 655 GLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLP 714

Query: 320 GPTGKKGSRGFKGSKGE--LARVP 341
           GP G  G  G KG +G+  LA +P
Sbjct: 715 GPQGPIGPPGEKGPQGKPGLAGLP 738



 Score =  155 bits (392), Expect = 8e-38
 Identities = 107/299 (35%), Positives = 128/299 (42%), Gaps = 46/299 (15%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGE----------- 156
           V G  G  G  G  GP G  G  G PG PG  GP G  G  G  GL G            
Sbjct: 452 VEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRY 511

Query: 157 ----------------------------RGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGG 188
                                       RG  G  G  G+PG  G PG  G KG  G  G
Sbjct: 512 GGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPG 571

Query: 189 VKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSG 248
            +G +G +G        G++G  GA G  G+ G PGAKG++G  G  G  GDKG  G+ G
Sbjct: 572 PQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERG 631

Query: 249 ERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGL------PGAKGDPGIKGEKGELGPPG 302
            +G  G  G+ GM+GE G  G  G+ G++G  GL      PGA G PG+ G  G  GP G
Sbjct: 632 PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKG 691

Query: 303 LLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPPPNIPIK 361
            +GP G  G  G +G  GP G  G +G  G  GE     +    AGL     PP  P K
Sbjct: 692 NMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGL-AGLPGADGPPGHPGK 749



 Score =  100 bits (248), Expect = 4e-21
 Identities = 55/129 (42%), Positives = 69/129 (53%), Gaps = 12/129 (9%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGL---------KGERG 158
            +PG  GE G  G  G  G  G +G PG PG+ G  G +G KG  GL         +GE+G
Sbjct: 1424 IPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKG 1483

Query: 159  DQGVPGYPGKPGAQGE---PGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMG 215
            D+G+PG  G PGA+G+   PGP G  G  G  G+ G +G KG+       G+KGD G  G
Sbjct: 1484 DRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPG 1543

Query: 216  SPGLHGGPG 224
             PG  G PG
Sbjct: 1544 PPGSPGPPG 1552



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 37/78 (47%), Positives = 47/78 (60%), Gaps = 12/78 (15%)

Query: 109  PGQKGEPGETGQPGPKGEAG---NLGIPGPP---------GVVGPQGPRGYKGEKGLKGE 156
            PG++GE G+ G PG +G  G   + GIPGP          G+ GPQGP+G KG  G  G+
Sbjct: 1476 PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQ 1535

Query: 157  RGDQGVPGYPGKPGAQGE 174
            +GD G+PG PG PG  GE
Sbjct: 1536 KGDSGLPGPPGSPGPPGE 1553



 Score = 69.7 bits (169), Expect = 5e-12
 Identities = 53/143 (37%), Positives = 61/143 (42%), Gaps = 30/143 (20%)

Query: 220 HGGPGAKGEKGE--MGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKS 277
           HG  G KG+KGE  + E G + +    G  G  G  G  G  G++G  G  GD G  G  
Sbjct: 431 HGAYGEKGQKGEPAVVEPGMLVE----GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPP 486

Query: 278 GRNGLPGAKGDPGIKGEKGEL----GPPGLLGPT--------------------GPKGDI 313
           GR GLPGA G PG  G    L    G  G  GPT                    GP G +
Sbjct: 487 GRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPM 546

Query: 314 GNKGVRGPTGKKGSRGFKGSKGE 336
           G  G  GP G  GS G KG  G+
Sbjct: 547 GLTGRPGPVGGPGSSGAKGESGD 569



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 16/30 (53%), Positives = 16/30 (53%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVV 139
            G KG  G  GQ G  G  G  G PGPPG V
Sbjct: 1525 GNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1554


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  199 bits (505), Expect = 6e-51
 Identities = 122/292 (41%), Positives = 148/292 (50%), Gaps = 27/292 (9%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
            G+KGEPGE G PGP GEAG  G  G  G  G  GP G  G  G KG  GD G  G PG  
Sbjct: 1213 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1272

Query: 170  GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
            G  G+PGP G+ G  G  GV G KG  GD       G  G+ G  G PG  G PGA G +
Sbjct: 1273 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1332

Query: 230  GEMGEKGEMGDKGC------CGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRN--- 280
            G  GEKG  G+ G        G  G +G  G+ G  G++G  G  G+ G+ G +G++   
Sbjct: 1333 GRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1392

Query: 281  ------GLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSK 334
                  GLPG KGDPG KGEKG    PGL+G  GP G+ G KG RG  G +GS G KG  
Sbjct: 1393 GPMGPPGLPGLKGDPGSKGEKGH---PGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG 1449

Query: 335  GELARVPRSAFSAGLSKPFPPPNIPIKFEKILYNDQGNYSPVTGKFNCSIPG 386
            G    +P  A   G   P  PP +P    +    ++G+  P   K +  +PG
Sbjct: 1450 G----IPGPAGPLG---PPGPPGLP--GPQGPKGNKGSTGPAGQKGDSGLPG 1492



 Score =  197 bits (500), Expect = 2e-50
 Identities = 107/234 (45%), Positives = 130/234 (55%), Gaps = 6/234 (2%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGP------RGYKGEKGLKGERGDQGV 162
           PG  G  GE+G PGP+G  G  G PGP G  G +G       RG  GE G KG+RG  G+
Sbjct: 507 PGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGL 566

Query: 163 PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
           PG PG  G +GE GP+G  G  G  G++G+ G  G        G +G  G  G+PG  G 
Sbjct: 567 PGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQ 626

Query: 223 PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGL 282
           PG  G  G  G KG MG +G  G  G++G  G +G  G +G  G  G+ G +GK G  GL
Sbjct: 627 PGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGL 686

Query: 283 PGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
           PGA G PG  G++G+ G  G LGP GP+G IG  G RG  G  G RG KGSKGE
Sbjct: 687 PGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 740



 Score =  195 bits (495), Expect = 9e-50
 Identities = 108/245 (44%), Positives = 133/245 (54%), Gaps = 27/245 (11%)

Query: 109 PGQKGEPGETGQPGPKGEAGN---LGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGY 165
           PG KG  G  G+PGP G+ GN    G+PGP G +GP G +G +G+ GL G  G  G PG+
Sbjct: 636 PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 695

Query: 166 PGKPGAQGE------PGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGL 219
           PGK G  GE      PGP+G  G  G  GVKG  G +G       KG KG++G  G PG 
Sbjct: 696 PGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRG------LKGSKGEKGEDGFPGF 749

Query: 220 HGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGR 279
            G  G KG++GE+G+ G  G+ G  G  G  G  G  G  G  GEKG  G  G+ G  GR
Sbjct: 750 KGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGR 809

Query: 280 N---------GLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGF 330
                     G PGA G+ G +G  G+ GP G  GPTGP+   G++G RGPTGK G +G 
Sbjct: 810 QGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPR---GSRGARGPTGKPGPKGT 866

Query: 331 KGSKG 335
            G  G
Sbjct: 867 SGGDG 871



 Score =  193 bits (490), Expect = 3e-49
 Identities = 103/234 (44%), Positives = 131/234 (55%), Gaps = 6/234 (2%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
           +PG KG  GE G  GP G  G+ G+ G  G +GP+G  G  G +GL G RG  G PG PG
Sbjct: 569 LPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPG 628

Query: 168 KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGD---TCGNCTKGEKGDQGAMGSPGLHGGPG 224
             G  G PGPKG+ G  G  G  GQ+G+ G           G  G++G  G PGL G PG
Sbjct: 629 MAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPG 688

Query: 225 AKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPG 284
           A G  G  G++G+ G+KG  G  G +G  G  G  G+KG  G +G  G +G+ G +G PG
Sbjct: 689 ADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG 748

Query: 285 AKGDPGIKGEKGE---LGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
            KGD G+KG++GE   +GP G  GP GPKG  G  G  GP+G+ G +G  G  G
Sbjct: 749 FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG 802



 Score =  190 bits (483), Expect = 2e-48
 Identities = 99/237 (41%), Positives = 134/237 (56%), Gaps = 9/237 (3%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
           +PG  G PG  G+ G  GE G LG PGP G +G  GPRG KG  G++G +G +G  G  G
Sbjct: 686 LPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDG 745

Query: 168 KPGAQGEPGPKGDKGNIGLGGVKGQ------KGSKGDTCGNCTKGEKGDQGAMGSPGLHG 221
            PG +G+ G KGD+G +G  G +G+      KG  G T      G+ G++G +G PGL G
Sbjct: 746 FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG 805

Query: 222 GPGAKGEKGEM---GEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSG 278
            PG +G KG     G  G  G+KG  G +G+ G +GQ+G  G +G +G++G +G  G  G
Sbjct: 806 YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 865

Query: 279 RNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
            +G  G  G PG +G +G  GP G  GP GP G  G  G+ G  G++G  GF+G  G
Sbjct: 866 TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 922



 Score =  190 bits (482), Expect = 3e-48
 Identities = 112/253 (44%), Positives = 127/253 (50%), Gaps = 27/253 (10%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGP------------QGPRGYKGEKGLKGER 157
            G KGE GE GQ G KG+ G  G PGPPG+ GP             GPRG +G  G KG+ 
Sbjct: 1087 GDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDE 1146

Query: 158  GDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSP 217
            G +G PG PG  G QG PGP G+KG  G  G  G  G  G        G  G QG  GS 
Sbjct: 1147 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV 1206

Query: 218  GLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKS 277
            G  GG G KGE GE G  G  G+ G  G  GERG KG+ G  G  G  G+KG  G +G  
Sbjct: 1207 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK 1266

Query: 278  GRNGLPGAKGDP------------GIKGEKGELGPPGLLGPTGPKGDI---GNKGVRGPT 322
            G  G  G  GDP            G+ G+KGE G PG  GP GP G+    G  G RGP 
Sbjct: 1267 GNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPP 1326

Query: 323  GKKGSRGFKGSKG 335
            G  G+ G +G KG
Sbjct: 1327 GAAGAEGRQGEKG 1339



 Score =  190 bits (482), Expect = 3e-48
 Identities = 108/248 (43%), Positives = 122/248 (49%), Gaps = 21/248 (8%)

Query: 109  PGQKGEPGETGQPG---PKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGY 165
            PG  G PG  G PG   PKG  G +G PG PG  G  GP G  G  G KGE GD G PG 
Sbjct: 1248 PGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGP 1307

Query: 166  PGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGA 225
            PG  G  G PGP G +G  G  G +G++G KG       +G  G  G +G  G  G PG 
Sbjct: 1308 PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1367

Query: 226  KGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGM------------ 273
            +G +G  G  GE G  G  G  G  G  G  G  G+KG+ GSKG+ G             
Sbjct: 1368 EGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGE 1427

Query: 274  ------EGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGS 327
                   G  G  G PGAKGD GI G  G LGPPG  G  GP+G  GNKG  GP G+KG 
Sbjct: 1428 QGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGD 1487

Query: 328  RGFKGSKG 335
             G  G  G
Sbjct: 1488 SGLPGPPG 1495



 Score =  189 bits (481), Expect = 4e-48
 Identities = 108/254 (42%), Positives = 127/254 (50%), Gaps = 33/254 (12%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG+ G PG  GQ G  G  G  G PGP GVVGPQGP G  G  G +G  G  G PG  G 
Sbjct: 900  PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGL 959

Query: 169  PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGE 228
            PGA G+ G KGD G  G+ G  G  G +G        GE+G  GA G+PGL GG G +G 
Sbjct: 960  PGAAGKEGAKGDPGPQGISGKDGPAGLRG------FPGERGLPGAQGAPGLKGGEGPQGP 1013

Query: 229  KGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGL------ 282
             G +G  GE G  G  G  G  G  G +G  G  GEKG+ G+ G +G +GR+G+      
Sbjct: 1014 PGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGL 1073

Query: 283  ---------------------PGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGP 321
                                 PG KG  G KGE G  GPPGL GP G  G  G  G  GP
Sbjct: 1074 PGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGP 1133

Query: 322  TGKKGSRGFKGSKG 335
             G++G  G KG +G
Sbjct: 1134 RGQQGMFGQKGDEG 1147



 Score =  188 bits (478), Expect = 8e-48
 Identities = 106/240 (44%), Positives = 125/240 (52%), Gaps = 12/240 (5%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG  GE G  G+ GP+G AG  G+ GP G+ GP GP G  GE G KGE G+ G  G  G 
Sbjct: 1044 PGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGD 1103

Query: 169  PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSP------GLHGG 222
             G  G PGP G +G +G  G+ G  G  G        G+KGD+GA G P      GL G 
Sbjct: 1104 KGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGL 1163

Query: 223  PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGL 282
            PG  GEKGE G+ G MG  G  G  G +G  G  G  G  G  GS G  G +G+ G  G 
Sbjct: 1164 PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGN 1223

Query: 283  PGAKGDPGI------KGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
            PG  G+ G+      +GEKGE GPPG  GP G KG  G+ G +G  G  G  G  G  GE
Sbjct: 1224 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1283



 Score =  188 bits (477), Expect = 1e-47
 Identities = 112/270 (41%), Positives = 135/270 (50%), Gaps = 42/270 (15%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGP---RGYKGEK---------GLKGE 156
            PG  G PGE G PG  G+ G  G PGP G+ G  GP   RG+ GE+         GLKG 
Sbjct: 948  PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1007

Query: 157  RGDQGVP------------------GYPGKPGAQGEPGPKGDK---------GNIGLGGV 189
             G QG P                  G PG+PG QG PGP G+K         G  G  GV
Sbjct: 1008 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGV 1067

Query: 190  KGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGE---KGEMGDKGCCGD 246
            +G  G  G      + GE GD+G +G PG  G  G KGE G  G    +G +G  G  G 
Sbjct: 1068 QGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG 1127

Query: 247  SGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGP 306
             GE G +GQ+G  G KG++G++G  G  G  G  GLPG  G+ G  G+ G +GPPG  GP
Sbjct: 1128 DGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGP 1187

Query: 307  TGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
             GP+G  G  G +GP G  GS G  G KGE
Sbjct: 1188 RGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1217



 Score =  187 bits (475), Expect = 2e-47
 Identities = 115/262 (43%), Positives = 135/262 (51%), Gaps = 24/262 (9%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGL---KGERGDQGVPGY 165
           PGQ G  G  G PGPKG  G  G PGPPG  G  GP+G  G +G     GE+G QG PG 
Sbjct: 624 PGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGL 683

Query: 166 PGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGA 225
            G PGA G PG  G +G  G  G  G  G +G        G  G +G  G+ G+ G  G+
Sbjct: 684 AGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPI------GYPGPRGVKGADGVRGLKGS 737

Query: 226 KGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEK------GSKGDSGMEGKSGR 279
           KGEKGE G  G  GD G  GD GE G  G +GE G +G K      G  G SG  G+ G+
Sbjct: 738 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 797

Query: 280 NGLPGAKGDPGIKGEKGELGPPGLLGPTGPK------GDIGNKGVRGPTGKKGSRGFKGS 333
            G+PG  G PG +G KG  G PG  G  G K      G  G +G RGPTG +GSRG +G 
Sbjct: 798 LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 857

Query: 334 KGELARVPRSAFSAGLSKPFPP 355
            G+    P+   S G   P PP
Sbjct: 858 TGKPG--PKGT-SGGDGPPGPP 876



 Score =  186 bits (473), Expect = 3e-47
 Identities = 114/257 (44%), Positives = 128/257 (49%), Gaps = 33/257 (12%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPG----- 164
            G +G PG  G PG +G AG  G  G PG  GPQGP G  GEKG  GE+G QG  G     
Sbjct: 1009 GPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQ 1068

Query: 165  ----YPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLH 220
                 PG  G  G PG  GDKG IG     GQKGSKGD   N   G  G QG +G+PG+ 
Sbjct: 1069 GPVGLPGPAGPAGSPGEDGDKGEIG---EPGQKGSKGDKGENGPPGPPGLQGPVGAPGIA 1125

Query: 221  GGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGD---------S 271
            GG G  G +G+ G  G+ GD+G  G  G  G  G +G  G  GEKG  GD          
Sbjct: 1126 GGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPP 1185

Query: 272  GMEGKSGRNGLPGAKGDPGI---------KGEKGEL---GPPGLLGPTGPKGDIGNKGVR 319
            G  G  G NG  G +G PG          KGE GE    GPPG  G  GPKG+ G KG  
Sbjct: 1186 GPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEA 1245

Query: 320  GPTGKKGSRGFKGSKGE 336
            GP G  G  G KG  G+
Sbjct: 1246 GPPGAAGPPGAKGPPGD 1262



 Score =  185 bits (470), Expect = 7e-47
 Identities = 113/268 (42%), Positives = 134/268 (50%), Gaps = 25/268 (9%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGV------VGPQGPRGYKGEKGLKGERGDQGVP 163
            GQKG+ G  G PGP G  G  G+PGPPG       VGP GP G  G +G +G  G  G  
Sbjct: 1141 GQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1200

Query: 164  GYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGP 223
            G PG  G+ G  G KG+ G  G  G  G+ G  G       KGE+G++G  G PG  G P
Sbjct: 1201 GPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGG------PKGERGEKGEAGPPGAAGPP 1254

Query: 224  GAKGEKGEMGEKGEMGDKGCCGD---SGERGGKGQKGEGGMKGEKGS---------KGDS 271
            GAKG  G+ G KG  G  G  GD    GE G  GQ G GG KGE G           G++
Sbjct: 1255 GAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEA 1314

Query: 272  GMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFK 331
            G  G  G+ G PGA G  G +GEKG  G  G  GP G  G +G +G  G  G +G RG  
Sbjct: 1315 GPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIP 1374

Query: 332  GSKGELARVPRSAFSAGLSKPFPPPNIP 359
            G  GE   +P +A   G   P  PP +P
Sbjct: 1375 GPVGEQG-LPGAAGQDGPPGPMGPPGLP 1401



 Score =  184 bits (467), Expect = 2e-46
 Identities = 102/226 (45%), Positives = 123/226 (54%), Gaps = 3/226 (1%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
            G +G  G TG+PGPKG +G  G PGPPG  GPQGP+G  G  G KG  G  G  G PG P
Sbjct: 850  GSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHP 909

Query: 170  GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
            G +GE G +G  G  G GGV G +G  G+T      GE+G  G  G PG  G PGA G++
Sbjct: 910  GQRGETGFQGKTGPPGPGGVVGPQGPTGET---GPIGERGHPGPPGPPGEQGLPGAAGKE 966

Query: 230  GEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDP 289
            G  G+ G  G  G  G +G RG  G++G  G +G  G KG  G +G  G  G PG +G  
Sbjct: 967  GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA 1026

Query: 290  GIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
            G  G  G  G PG  GP GP G+ G  G +GP G  G  G +G  G
Sbjct: 1027 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG 1072



 Score =  182 bits (462), Expect = 6e-46
 Identities = 105/264 (39%), Positives = 137/264 (51%), Gaps = 14/264 (5%)

Query: 110  GQKGEPGETGQPGPKGEAGN---LGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYP 166
            G KG  G TG PGP G+AG    LG+PG PG  G QGP+G  G  G  G  G++G  G  
Sbjct: 775  GPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA 834

Query: 167  GKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAK 226
            GKPG +G+ GP G +G+ G  G  G+ G KG + G+   G  G++G  G  G  G PG K
Sbjct: 835  GKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPK 894

Query: 227  GEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAK 286
            G  G  G+ G  G  G  G++G +G  G  G GG+ G +G  G++G  G+ G  G PG  
Sbjct: 895  GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 954

Query: 287  GDPGI------KGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGEL--- 337
            G+ G+      +G KG+ GP G+ G  GP G  G  G RG  G +G+ G KG +G     
Sbjct: 955  GEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPP 1014

Query: 338  --ARVPRSAFSAGLSKPFPPPNIP 359
                 P    SAG + P   P  P
Sbjct: 1015 GPVGSPGERGSAGTAGPIGLPGRP 1038



 Score =  178 bits (452), Expect = 8e-45
 Identities = 102/249 (40%), Positives = 119/249 (47%), Gaps = 24/249 (9%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG KG  G  G PGP GE G  G  GP G  GP+GP G  G+ GL G  G +G  G+ GK
Sbjct: 861  PGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGK 920

Query: 169  P---------------------GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGE 207
                                  G +G PGP G  G  GL G  G++G+KGD       G+
Sbjct: 921  TGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 980

Query: 208  KGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGS 267
             G  G  G PG  G PGA+G  G  G +G  G  G  G  GERG  G  G  G+ G  G 
Sbjct: 981  DGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP 1040

Query: 268  KGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGS 327
            +G     G +G  G PG KG  G  G  G  GP GL GP GP G  G  G +G  G+ G 
Sbjct: 1041 QGP---PGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ 1097

Query: 328  RGFKGSKGE 336
            +G KG KGE
Sbjct: 1098 KGSKGDKGE 1106



 Score =  174 bits (440), Expect = 2e-43
 Identities = 111/284 (39%), Positives = 135/284 (47%), Gaps = 29/284 (10%)

Query: 110 GQKGEPG--ETGQ--PGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGY 165
           GQKGEP   E G    GP G AG  GI GPPG+ GP GP          G+ GD+G PG 
Sbjct: 387 GQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGP---------PGDPGDRGPPGR 437

Query: 166 PGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGN--------------CTKGEKGDQ 211
           PG PGA G PGP G    + L    G  GSKG T                   +G  G  
Sbjct: 438 PGLPGADGLPGPPGTM--LMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPM 495

Query: 212 GAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDS 271
           G  G PG  GGPG+ G KGE G+ G  G +G  G  G  G  G++G  G  G +G  G+ 
Sbjct: 496 GLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEP 555

Query: 272 GMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFK 331
           G +G  G +GLPG  GD G +GE+G  GPPG  G  G +G+ G  G RG  G+ G RG  
Sbjct: 556 GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 615

Query: 332 GSKGELARVPRSAFSAGLSKPFPPPNIPIKFEKILYNDQGNYSP 375
           G +G      +   +     P P  N+  + E      QGN  P
Sbjct: 616 GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 659



 Score =  169 bits (429), Expect = 4e-42
 Identities = 98/239 (41%), Positives = 126/239 (52%), Gaps = 21/239 (8%)

Query: 110 GQKGEPGETGQPG------PKGEAGNLGIPGPPGVVGPQGPRGYKG---EKGLKGERGDQ 160
           G KGE GE G PG       KG+ G +G  GP G  GP+GP+G  G   + G  G+ G++
Sbjct: 736 GSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEK 795

Query: 161 GVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLH 220
           G  G PG PG  G  GPKG  G  G  G  G+KG++G        G+ G +G  G  G  
Sbjct: 796 GKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARG------VAGKPGPRGQRGPTGPR 849

Query: 221 GGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRN 280
           G  GA+G  G+ G KG  G  G  G  GERG +G +G  G  G KG  G     GK G  
Sbjct: 850 GSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGP---PGKDGLP 906

Query: 281 GLPGAKGDPGIKGEKGELGPPGLLGPTGPKGD---IGNKGVRGPTGKKGSRGFKGSKGE 336
           G PG +G+ G +G+ G  GP G++GP GP G+   IG +G  GP G  G +G  G+ G+
Sbjct: 907 GHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 965



 Score =  169 bits (428), Expect = 5e-42
 Identities = 106/263 (40%), Positives = 128/263 (48%), Gaps = 13/263 (4%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVG------PQGPRGYKGEKGLKGERGDQGV 162
           PG  G  G  G+PG KG+ G  G+PG PG  G      PQGP G  G+ G++GE G+ G 
Sbjct: 543 PGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP 602

Query: 163 PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
            G PG+ G +G  GP+G  G  G  G+ G  G  G       +GE G  G  G+PG  G 
Sbjct: 603 RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 662

Query: 223 PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGK---SGR 279
           PG +G  G  GEKG  G  G  G  G  G  G  G+ G  GEKG+ G  G +G     G 
Sbjct: 663 PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGP 722

Query: 280 NGLPGAKGDPGIKGEKGELGP---PGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
            G+ GA G  G+KG KGE G    PG  G  G KGD G  G  GP G+ G  G KG  G 
Sbjct: 723 RGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP 782

Query: 337 LARVPRSAFSAGLSKPFPPPNIP 359
               P  +  AG       P +P
Sbjct: 783 TGD-PGPSGQAGEKGKLGVPGLP 804



 Score =  168 bits (426), Expect = 9e-42
 Identities = 99/245 (40%), Positives = 125/245 (51%), Gaps = 21/245 (8%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           G  G  G TG+PGP G  G+ G  G  G  GPQGPRG +G  G  G+ G +G PG  G  
Sbjct: 490 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 549

Query: 170 GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
           G  GEPG KGD+G  GL G+ G KG +G         E+G QG          PG  G+ 
Sbjct: 550 GMPGEPGAKGDRGFDGLPGLPGDKGHRG---------ERGPQGP---------PGPPGDD 591

Query: 230 GEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDP 289
           G  GE GE+G +G  G++G RG  G +G  G  G+ G    +G++G  G  G  G +G+P
Sbjct: 592 GMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM---AGVDGPPGPKGNMGPQGEP 648

Query: 290 GIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGL 349
           G  G++G  GP GL GP GP G  G KG +G  G  G  G  G  G   +  +S     L
Sbjct: 649 GPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL 708

Query: 350 SKPFP 354
             P P
Sbjct: 709 GPPGP 713



 Score =  166 bits (421), Expect = 3e-41
 Identities = 101/264 (38%), Positives = 127/264 (48%), Gaps = 32/264 (12%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVV----------GPQGP--------------- 144
           G  G+PG+ G PG  G  G  G+PGPPG +          G +GP               
Sbjct: 424 GPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQ 483

Query: 145 -----RGYKGEKGLKGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDT 199
                RG  G  GL G  G  G PG  G  G  G+PGP+G +G  G  G  G+ G +G  
Sbjct: 484 ARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRP 543

Query: 200 CGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEG 259
             +  +G  G+ GA G  G  G PG  G+KG  GE+G  G  G  GD G RG  G+ G  
Sbjct: 544 GADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPR 603

Query: 260 GMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVR 319
           G+ GE G +G  G  G  G  G PG  G  G  G KG +GP G  GP G +G+ G +G+ 
Sbjct: 604 GLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLP 663

Query: 320 GPTGKKGSRGFKGSKGE--LARVP 341
           GP G  G  G KG +G+  LA +P
Sbjct: 664 GPQGPIGPPGEKGPQGKPGLAGLP 687



 Score =  155 bits (392), Expect = 8e-38
 Identities = 107/299 (35%), Positives = 128/299 (42%), Gaps = 46/299 (15%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGE----------- 156
           V G  G  G  G  GP G  G  G PG PG  GP G  G  G  GL G            
Sbjct: 401 VEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRY 460

Query: 157 ----------------------------RGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGG 188
                                       RG  G  G  G+PG  G PG  G KG  G  G
Sbjct: 461 GGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPG 520

Query: 189 VKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSG 248
            +G +G +G        G++G  GA G  G+ G PGAKG++G  G  G  GDKG  G+ G
Sbjct: 521 PQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERG 580

Query: 249 ERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGL------PGAKGDPGIKGEKGELGPPG 302
            +G  G  G+ GM+GE G  G  G+ G++G  GL      PGA G PG+ G  G  GP G
Sbjct: 581 PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKG 640

Query: 303 LLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPPPNIPIK 361
            +GP G  G  G +G  GP G  G +G  G  GE     +    AGL     PP  P K
Sbjct: 641 NMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGL-AGLPGADGPPGHPGK 698



 Score =  100 bits (248), Expect = 4e-21
 Identities = 55/129 (42%), Positives = 69/129 (53%), Gaps = 12/129 (9%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGL---------KGERG 158
            +PG  GE G  G  G  G  G +G PG PG+ G  G +G KG  GL         +GE+G
Sbjct: 1373 IPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKG 1432

Query: 159  DQGVPGYPGKPGAQGE---PGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMG 215
            D+G+PG  G PGA+G+   PGP G  G  G  G+ G +G KG+       G+KGD G  G
Sbjct: 1433 DRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPG 1492

Query: 216  SPGLHGGPG 224
             PG  G PG
Sbjct: 1493 PPGSPGPPG 1501



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 37/78 (47%), Positives = 47/78 (60%), Gaps = 12/78 (15%)

Query: 109  PGQKGEPGETGQPGPKGEAG---NLGIPGPP---------GVVGPQGPRGYKGEKGLKGE 156
            PG++GE G+ G PG +G  G   + GIPGP          G+ GPQGP+G KG  G  G+
Sbjct: 1425 PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQ 1484

Query: 157  RGDQGVPGYPGKPGAQGE 174
            +GD G+PG PG PG  GE
Sbjct: 1485 KGDSGLPGPPGSPGPPGE 1502



 Score = 69.7 bits (169), Expect = 5e-12
 Identities = 53/143 (37%), Positives = 61/143 (42%), Gaps = 30/143 (20%)

Query: 220 HGGPGAKGEKGE--MGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKS 277
           HG  G KG+KGE  + E G + +    G  G  G  G  G  G++G  G  GD G  G  
Sbjct: 380 HGAYGEKGQKGEPAVVEPGMLVE----GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPP 435

Query: 278 GRNGLPGAKGDPGIKGEKGEL----GPPGLLGPT--------------------GPKGDI 313
           GR GLPGA G PG  G    L    G  G  GPT                    GP G +
Sbjct: 436 GRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPM 495

Query: 314 GNKGVRGPTGKKGSRGFKGSKGE 336
           G  G  GP G  GS G KG  G+
Sbjct: 496 GLTGRPGPVGGPGSSGAKGESGD 518



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 16/30 (53%), Positives = 16/30 (53%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVV 139
            G KG  G  GQ G  G  G  G PGPPG V
Sbjct: 1474 GNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1503


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  199 bits (505), Expect = 6e-51
 Identities = 122/292 (41%), Positives = 148/292 (50%), Gaps = 27/292 (9%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
            G+KGEPGE G PGP GEAG  G  G  G  G  GP G  G  G KG  GD G  G PG  
Sbjct: 1252 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1311

Query: 170  GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
            G  G+PGP G+ G  G  GV G KG  GD       G  G+ G  G PG  G PGA G +
Sbjct: 1312 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1371

Query: 230  GEMGEKGEMGDKGC------CGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRN--- 280
            G  GEKG  G+ G        G  G +G  G+ G  G++G  G  G+ G+ G +G++   
Sbjct: 1372 GRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1431

Query: 281  ------GLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSK 334
                  GLPG KGDPG KGEKG    PGL+G  GP G+ G KG RG  G +GS G KG  
Sbjct: 1432 GPMGPPGLPGLKGDPGSKGEKGH---PGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG 1488

Query: 335  GELARVPRSAFSAGLSKPFPPPNIPIKFEKILYNDQGNYSPVTGKFNCSIPG 386
            G    +P  A   G   P  PP +P    +    ++G+  P   K +  +PG
Sbjct: 1489 G----IPGPAGPLG---PPGPPGLP--GPQGPKGNKGSTGPAGQKGDSGLPG 1531



 Score =  197 bits (500), Expect = 2e-50
 Identities = 107/234 (45%), Positives = 130/234 (55%), Gaps = 6/234 (2%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGP------RGYKGEKGLKGERGDQGV 162
           PG  G  GE+G PGP+G  G  G PGP G  G +G       RG  GE G KG+RG  G+
Sbjct: 546 PGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGL 605

Query: 163 PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
           PG PG  G +GE GP+G  G  G  G++G+ G  G        G +G  G  G+PG  G 
Sbjct: 606 PGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQ 665

Query: 223 PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGL 282
           PG  G  G  G KG MG +G  G  G++G  G +G  G +G  G  G+ G +GK G  GL
Sbjct: 666 PGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGL 725

Query: 283 PGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
           PGA G PG  G++G+ G  G LGP GP+G IG  G RG  G  G RG KGSKGE
Sbjct: 726 PGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 779



 Score =  195 bits (495), Expect = 9e-50
 Identities = 108/245 (44%), Positives = 133/245 (54%), Gaps = 27/245 (11%)

Query: 109 PGQKGEPGETGQPGPKGEAGN---LGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGY 165
           PG KG  G  G+PGP G+ GN    G+PGP G +GP G +G +G+ GL G  G  G PG+
Sbjct: 675 PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 734

Query: 166 PGKPGAQGE------PGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGL 219
           PGK G  GE      PGP+G  G  G  GVKG  G +G       KG KG++G  G PG 
Sbjct: 735 PGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRG------LKGSKGEKGEDGFPGF 788

Query: 220 HGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGR 279
            G  G KG++GE+G+ G  G+ G  G  G  G  G  G  G  GEKG  G  G+ G  GR
Sbjct: 789 KGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGR 848

Query: 280 N---------GLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGF 330
                     G PGA G+ G +G  G+ GP G  GPTGP+   G++G RGPTGK G +G 
Sbjct: 849 QGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPR---GSRGARGPTGKPGPKGT 905

Query: 331 KGSKG 335
            G  G
Sbjct: 906 SGGDG 910



 Score =  193 bits (490), Expect = 3e-49
 Identities = 103/234 (44%), Positives = 131/234 (55%), Gaps = 6/234 (2%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
           +PG KG  GE G  GP G  G+ G+ G  G +GP+G  G  G +GL G RG  G PG PG
Sbjct: 608 LPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPG 667

Query: 168 KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGD---TCGNCTKGEKGDQGAMGSPGLHGGPG 224
             G  G PGPKG+ G  G  G  GQ+G+ G           G  G++G  G PGL G PG
Sbjct: 668 MAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPG 727

Query: 225 AKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPG 284
           A G  G  G++G+ G+KG  G  G +G  G  G  G+KG  G +G  G +G+ G +G PG
Sbjct: 728 ADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG 787

Query: 285 AKGDPGIKGEKGE---LGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
            KGD G+KG++GE   +GP G  GP GPKG  G  G  GP+G+ G +G  G  G
Sbjct: 788 FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG 841



 Score =  190 bits (483), Expect = 2e-48
 Identities = 99/237 (41%), Positives = 134/237 (56%), Gaps = 9/237 (3%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
           +PG  G PG  G+ G  GE G LG PGP G +G  GPRG KG  G++G +G +G  G  G
Sbjct: 725 LPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDG 784

Query: 168 KPGAQGEPGPKGDKGNIGLGGVKGQ------KGSKGDTCGNCTKGEKGDQGAMGSPGLHG 221
            PG +G+ G KGD+G +G  G +G+      KG  G T      G+ G++G +G PGL G
Sbjct: 785 FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG 844

Query: 222 GPGAKGEKGEM---GEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSG 278
            PG +G KG     G  G  G+KG  G +G+ G +GQ+G  G +G +G++G +G  G  G
Sbjct: 845 YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 904

Query: 279 RNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
            +G  G  G PG +G +G  GP G  GP GP G  G  G+ G  G++G  GF+G  G
Sbjct: 905 TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 961



 Score =  190 bits (482), Expect = 3e-48
 Identities = 112/253 (44%), Positives = 127/253 (50%), Gaps = 27/253 (10%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGP------------QGPRGYKGEKGLKGER 157
            G KGE GE GQ G KG+ G  G PGPPG+ GP             GPRG +G  G KG+ 
Sbjct: 1126 GDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDE 1185

Query: 158  GDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSP 217
            G +G PG PG  G QG PGP G+KG  G  G  G  G  G        G  G QG  GS 
Sbjct: 1186 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV 1245

Query: 218  GLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKS 277
            G  GG G KGE GE G  G  G+ G  G  GERG KG+ G  G  G  G+KG  G +G  
Sbjct: 1246 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK 1305

Query: 278  GRNGLPGAKGDP------------GIKGEKGELGPPGLLGPTGPKGDI---GNKGVRGPT 322
            G  G  G  GDP            G+ G+KGE G PG  GP GP G+    G  G RGP 
Sbjct: 1306 GNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPP 1365

Query: 323  GKKGSRGFKGSKG 335
            G  G+ G +G KG
Sbjct: 1366 GAAGAEGRQGEKG 1378



 Score =  190 bits (482), Expect = 3e-48
 Identities = 108/248 (43%), Positives = 122/248 (49%), Gaps = 21/248 (8%)

Query: 109  PGQKGEPGETGQPG---PKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGY 165
            PG  G PG  G PG   PKG  G +G PG PG  G  GP G  G  G KGE GD G PG 
Sbjct: 1287 PGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGP 1346

Query: 166  PGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGA 225
            PG  G  G PGP G +G  G  G +G++G KG       +G  G  G +G  G  G PG 
Sbjct: 1347 PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1406

Query: 226  KGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGM------------ 273
            +G +G  G  GE G  G  G  G  G  G  G  G+KG+ GSKG+ G             
Sbjct: 1407 EGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGE 1466

Query: 274  ------EGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGS 327
                   G  G  G PGAKGD GI G  G LGPPG  G  GP+G  GNKG  GP G+KG 
Sbjct: 1467 QGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGD 1526

Query: 328  RGFKGSKG 335
             G  G  G
Sbjct: 1527 SGLPGPPG 1534



 Score =  189 bits (481), Expect = 4e-48
 Identities = 108/254 (42%), Positives = 127/254 (50%), Gaps = 33/254 (12%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG+ G PG  GQ G  G  G  G PGP GVVGPQGP G  G  G +G  G  G PG  G 
Sbjct: 939  PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGL 998

Query: 169  PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGE 228
            PGA G+ G KGD G  G+ G  G  G +G        GE+G  GA G+PGL GG G +G 
Sbjct: 999  PGAAGKEGAKGDPGPQGISGKDGPAGLRG------FPGERGLPGAQGAPGLKGGEGPQGP 1052

Query: 229  KGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGL------ 282
             G +G  GE G  G  G  G  G  G +G  G  GEKG+ G+ G +G +GR+G+      
Sbjct: 1053 PGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGL 1112

Query: 283  ---------------------PGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGP 321
                                 PG KG  G KGE G  GPPGL GP G  G  G  G  GP
Sbjct: 1113 PGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGP 1172

Query: 322  TGKKGSRGFKGSKG 335
             G++G  G KG +G
Sbjct: 1173 RGQQGMFGQKGDEG 1186



 Score =  188 bits (478), Expect = 8e-48
 Identities = 106/240 (44%), Positives = 125/240 (52%), Gaps = 12/240 (5%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG  GE G  G+ GP+G AG  G+ GP G+ GP GP G  GE G KGE G+ G  G  G 
Sbjct: 1083 PGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGD 1142

Query: 169  PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSP------GLHGG 222
             G  G PGP G +G +G  G+ G  G  G        G+KGD+GA G P      GL G 
Sbjct: 1143 KGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGL 1202

Query: 223  PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGL 282
            PG  GEKGE G+ G MG  G  G  G +G  G  G  G  G  GS G  G +G+ G  G 
Sbjct: 1203 PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGN 1262

Query: 283  PGAKGDPGI------KGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
            PG  G+ G+      +GEKGE GPPG  GP G KG  G+ G +G  G  G  G  G  GE
Sbjct: 1263 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1322



 Score =  188 bits (477), Expect = 1e-47
 Identities = 112/270 (41%), Positives = 135/270 (50%), Gaps = 42/270 (15%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGP---RGYKGEK---------GLKGE 156
            PG  G PGE G PG  G+ G  G PGP G+ G  GP   RG+ GE+         GLKG 
Sbjct: 987  PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1046

Query: 157  RGDQGVP------------------GYPGKPGAQGEPGPKGDK---------GNIGLGGV 189
             G QG P                  G PG+PG QG PGP G+K         G  G  GV
Sbjct: 1047 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGV 1106

Query: 190  KGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGE---KGEMGDKGCCGD 246
            +G  G  G      + GE GD+G +G PG  G  G KGE G  G    +G +G  G  G 
Sbjct: 1107 QGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG 1166

Query: 247  SGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGP 306
             GE G +GQ+G  G KG++G++G  G  G  G  GLPG  G+ G  G+ G +GPPG  GP
Sbjct: 1167 DGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGP 1226

Query: 307  TGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
             GP+G  G  G +GP G  GS G  G KGE
Sbjct: 1227 RGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1256



 Score =  187 bits (475), Expect = 2e-47
 Identities = 115/262 (43%), Positives = 135/262 (51%), Gaps = 24/262 (9%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGL---KGERGDQGVPGY 165
           PGQ G  G  G PGPKG  G  G PGPPG  G  GP+G  G +G     GE+G QG PG 
Sbjct: 663 PGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGL 722

Query: 166 PGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGA 225
            G PGA G PG  G +G  G  G  G  G +G        G  G +G  G+ G+ G  G+
Sbjct: 723 AGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPI------GYPGPRGVKGADGVRGLKGS 776

Query: 226 KGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEK------GSKGDSGMEGKSGR 279
           KGEKGE G  G  GD G  GD GE G  G +GE G +G K      G  G SG  G+ G+
Sbjct: 777 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 836

Query: 280 NGLPGAKGDPGIKGEKGELGPPGLLGPTGPK------GDIGNKGVRGPTGKKGSRGFKGS 333
            G+PG  G PG +G KG  G PG  G  G K      G  G +G RGPTG +GSRG +G 
Sbjct: 837 LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 896

Query: 334 KGELARVPRSAFSAGLSKPFPP 355
            G+    P+   S G   P PP
Sbjct: 897 TGKPG--PKGT-SGGDGPPGPP 915



 Score =  186 bits (473), Expect = 3e-47
 Identities = 114/257 (44%), Positives = 128/257 (49%), Gaps = 33/257 (12%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPG----- 164
            G +G PG  G PG +G AG  G  G PG  GPQGP G  GEKG  GE+G QG  G     
Sbjct: 1048 GPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQ 1107

Query: 165  ----YPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLH 220
                 PG  G  G PG  GDKG IG     GQKGSKGD   N   G  G QG +G+PG+ 
Sbjct: 1108 GPVGLPGPAGPAGSPGEDGDKGEIG---EPGQKGSKGDKGENGPPGPPGLQGPVGAPGIA 1164

Query: 221  GGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGD---------S 271
            GG G  G +G+ G  G+ GD+G  G  G  G  G +G  G  GEKG  GD          
Sbjct: 1165 GGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPP 1224

Query: 272  GMEGKSGRNGLPGAKGDPGI---------KGEKGEL---GPPGLLGPTGPKGDIGNKGVR 319
            G  G  G NG  G +G PG          KGE GE    GPPG  G  GPKG+ G KG  
Sbjct: 1225 GPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEA 1284

Query: 320  GPTGKKGSRGFKGSKGE 336
            GP G  G  G KG  G+
Sbjct: 1285 GPPGAAGPPGAKGPPGD 1301



 Score =  185 bits (470), Expect = 7e-47
 Identities = 113/268 (42%), Positives = 134/268 (50%), Gaps = 25/268 (9%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGV------VGPQGPRGYKGEKGLKGERGDQGVP 163
            GQKG+ G  G PGP G  G  G+PGPPG       VGP GP G  G +G +G  G  G  
Sbjct: 1180 GQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1239

Query: 164  GYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGP 223
            G PG  G+ G  G KG+ G  G  G  G+ G  G       KGE+G++G  G PG  G P
Sbjct: 1240 GPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGG------PKGERGEKGEAGPPGAAGPP 1293

Query: 224  GAKGEKGEMGEKGEMGDKGCCGD---SGERGGKGQKGEGGMKGEKGS---------KGDS 271
            GAKG  G+ G KG  G  G  GD    GE G  GQ G GG KGE G           G++
Sbjct: 1294 GAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEA 1353

Query: 272  GMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFK 331
            G  G  G+ G PGA G  G +GEKG  G  G  GP G  G +G +G  G  G +G RG  
Sbjct: 1354 GPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIP 1413

Query: 332  GSKGELARVPRSAFSAGLSKPFPPPNIP 359
            G  GE   +P +A   G   P  PP +P
Sbjct: 1414 GPVGEQG-LPGAAGQDGPPGPMGPPGLP 1440



 Score =  184 bits (467), Expect = 2e-46
 Identities = 102/226 (45%), Positives = 123/226 (54%), Gaps = 3/226 (1%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
            G +G  G TG+PGPKG +G  G PGPPG  GPQGP+G  G  G KG  G  G  G PG P
Sbjct: 889  GSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHP 948

Query: 170  GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
            G +GE G +G  G  G GGV G +G  G+T      GE+G  G  G PG  G PGA G++
Sbjct: 949  GQRGETGFQGKTGPPGPGGVVGPQGPTGET---GPIGERGHPGPPGPPGEQGLPGAAGKE 1005

Query: 230  GEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDP 289
            G  G+ G  G  G  G +G RG  G++G  G +G  G KG  G +G  G  G PG +G  
Sbjct: 1006 GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA 1065

Query: 290  GIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
            G  G  G  G PG  GP GP G+ G  G +GP G  G  G +G  G
Sbjct: 1066 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG 1111



 Score =  182 bits (462), Expect = 6e-46
 Identities = 105/264 (39%), Positives = 137/264 (51%), Gaps = 14/264 (5%)

Query: 110  GQKGEPGETGQPGPKGEAGN---LGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYP 166
            G KG  G TG PGP G+AG    LG+PG PG  G QGP+G  G  G  G  G++G  G  
Sbjct: 814  GPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA 873

Query: 167  GKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAK 226
            GKPG +G+ GP G +G+ G  G  G+ G KG + G+   G  G++G  G  G  G PG K
Sbjct: 874  GKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPK 933

Query: 227  GEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAK 286
            G  G  G+ G  G  G  G++G +G  G  G GG+ G +G  G++G  G+ G  G PG  
Sbjct: 934  GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 993

Query: 287  GDPGI------KGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGEL--- 337
            G+ G+      +G KG+ GP G+ G  GP G  G  G RG  G +G+ G KG +G     
Sbjct: 994  GEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPP 1053

Query: 338  --ARVPRSAFSAGLSKPFPPPNIP 359
                 P    SAG + P   P  P
Sbjct: 1054 GPVGSPGERGSAGTAGPIGLPGRP 1077



 Score =  178 bits (452), Expect = 8e-45
 Identities = 102/249 (40%), Positives = 119/249 (47%), Gaps = 24/249 (9%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG KG  G  G PGP GE G  G  GP G  GP+GP G  G+ GL G  G +G  G+ GK
Sbjct: 900  PGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGK 959

Query: 169  P---------------------GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGE 207
                                  G +G PGP G  G  GL G  G++G+KGD       G+
Sbjct: 960  TGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 1019

Query: 208  KGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGS 267
             G  G  G PG  G PGA+G  G  G +G  G  G  G  GERG  G  G  G+ G  G 
Sbjct: 1020 DGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP 1079

Query: 268  KGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGS 327
            +G     G +G  G PG KG  G  G  G  GP GL GP GP G  G  G +G  G+ G 
Sbjct: 1080 QGP---PGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ 1136

Query: 328  RGFKGSKGE 336
            +G KG KGE
Sbjct: 1137 KGSKGDKGE 1145



 Score =  174 bits (440), Expect = 2e-43
 Identities = 111/284 (39%), Positives = 135/284 (47%), Gaps = 29/284 (10%)

Query: 110 GQKGEPG--ETGQ--PGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGY 165
           GQKGEP   E G    GP G AG  GI GPPG+ GP GP          G+ GD+G PG 
Sbjct: 426 GQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGP---------PGDPGDRGPPGR 476

Query: 166 PGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGN--------------CTKGEKGDQ 211
           PG PGA G PGP G    + L    G  GSKG T                   +G  G  
Sbjct: 477 PGLPGADGLPGPPGTM--LMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPM 534

Query: 212 GAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDS 271
           G  G PG  GGPG+ G KGE G+ G  G +G  G  G  G  G++G  G  G +G  G+ 
Sbjct: 535 GLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEP 594

Query: 272 GMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFK 331
           G +G  G +GLPG  GD G +GE+G  GPPG  G  G +G+ G  G RG  G+ G RG  
Sbjct: 595 GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 654

Query: 332 GSKGELARVPRSAFSAGLSKPFPPPNIPIKFEKILYNDQGNYSP 375
           G +G      +   +     P P  N+  + E      QGN  P
Sbjct: 655 GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 698



 Score =  169 bits (429), Expect = 4e-42
 Identities = 98/239 (41%), Positives = 126/239 (52%), Gaps = 21/239 (8%)

Query: 110  GQKGEPGETGQPG------PKGEAGNLGIPGPPGVVGPQGPRGYKG---EKGLKGERGDQ 160
            G KGE GE G PG       KG+ G +G  GP G  GP+GP+G  G   + G  G+ G++
Sbjct: 775  GSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEK 834

Query: 161  GVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLH 220
            G  G PG PG  G  GPKG  G  G  G  G+KG++G        G+ G +G  G  G  
Sbjct: 835  GKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARG------VAGKPGPRGQRGPTGPR 888

Query: 221  GGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRN 280
            G  GA+G  G+ G KG  G  G  G  GERG +G +G  G  G KG  G     GK G  
Sbjct: 889  GSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGP---PGKDGLP 945

Query: 281  GLPGAKGDPGIKGEKGELGPPGLLGPTGPKGD---IGNKGVRGPTGKKGSRGFKGSKGE 336
            G PG +G+ G +G+ G  GP G++GP GP G+   IG +G  GP G  G +G  G+ G+
Sbjct: 946  GHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 1004



 Score =  169 bits (428), Expect = 5e-42
 Identities = 106/263 (40%), Positives = 128/263 (48%), Gaps = 13/263 (4%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVG------PQGPRGYKGEKGLKGERGDQGV 162
           PG  G  G  G+PG KG+ G  G+PG PG  G      PQGP G  G+ G++GE G+ G 
Sbjct: 582 PGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP 641

Query: 163 PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
            G PG+ G +G  GP+G  G  G  G+ G  G  G       +GE G  G  G+PG  G 
Sbjct: 642 RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 701

Query: 223 PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGK---SGR 279
           PG +G  G  GEKG  G  G  G  G  G  G  G+ G  GEKG+ G  G +G     G 
Sbjct: 702 PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGP 761

Query: 280 NGLPGAKGDPGIKGEKGELGP---PGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
            G+ GA G  G+KG KGE G    PG  G  G KGD G  G  GP G+ G  G KG  G 
Sbjct: 762 RGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP 821

Query: 337 LARVPRSAFSAGLSKPFPPPNIP 359
               P  +  AG       P +P
Sbjct: 822 TGD-PGPSGQAGEKGKLGVPGLP 843



 Score =  168 bits (426), Expect = 9e-42
 Identities = 99/245 (40%), Positives = 125/245 (51%), Gaps = 21/245 (8%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           G  G  G TG+PGP G  G+ G  G  G  GPQGPRG +G  G  G+ G +G PG  G  
Sbjct: 529 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 588

Query: 170 GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
           G  GEPG KGD+G  GL G+ G KG +G         E+G QG          PG  G+ 
Sbjct: 589 GMPGEPGAKGDRGFDGLPGLPGDKGHRG---------ERGPQGP---------PGPPGDD 630

Query: 230 GEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDP 289
           G  GE GE+G +G  G++G RG  G +G  G  G+ G    +G++G  G  G  G +G+P
Sbjct: 631 GMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM---AGVDGPPGPKGNMGPQGEP 687

Query: 290 GIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGL 349
           G  G++G  GP GL GP GP G  G KG +G  G  G  G  G  G   +  +S     L
Sbjct: 688 GPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL 747

Query: 350 SKPFP 354
             P P
Sbjct: 748 GPPGP 752



 Score =  166 bits (421), Expect = 3e-41
 Identities = 101/264 (38%), Positives = 127/264 (48%), Gaps = 32/264 (12%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVV----------GPQGP--------------- 144
           G  G+PG+ G PG  G  G  G+PGPPG +          G +GP               
Sbjct: 463 GPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQ 522

Query: 145 -----RGYKGEKGLKGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDT 199
                RG  G  GL G  G  G PG  G  G  G+PGP+G +G  G  G  G+ G +G  
Sbjct: 523 ARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRP 582

Query: 200 CGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEG 259
             +  +G  G+ GA G  G  G PG  G+KG  GE+G  G  G  GD G RG  G+ G  
Sbjct: 583 GADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPR 642

Query: 260 GMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVR 319
           G+ GE G +G  G  G  G  G PG  G  G  G KG +GP G  GP G +G+ G +G+ 
Sbjct: 643 GLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLP 702

Query: 320 GPTGKKGSRGFKGSKGE--LARVP 341
           GP G  G  G KG +G+  LA +P
Sbjct: 703 GPQGPIGPPGEKGPQGKPGLAGLP 726



 Score =  155 bits (392), Expect = 8e-38
 Identities = 107/299 (35%), Positives = 128/299 (42%), Gaps = 46/299 (15%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGE----------- 156
           V G  G  G  G  GP G  G  G PG PG  GP G  G  G  GL G            
Sbjct: 440 VEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRY 499

Query: 157 ----------------------------RGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGG 188
                                       RG  G  G  G+PG  G PG  G KG  G  G
Sbjct: 500 GGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPG 559

Query: 189 VKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSG 248
            +G +G +G        G++G  GA G  G+ G PGAKG++G  G  G  GDKG  G+ G
Sbjct: 560 PQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERG 619

Query: 249 ERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGL------PGAKGDPGIKGEKGELGPPG 302
            +G  G  G+ GM+GE G  G  G+ G++G  GL      PGA G PG+ G  G  GP G
Sbjct: 620 PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKG 679

Query: 303 LLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPPPNIPIK 361
            +GP G  G  G +G  GP G  G +G  G  GE     +    AGL     PP  P K
Sbjct: 680 NMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGL-AGLPGADGPPGHPGK 737



 Score =  100 bits (248), Expect = 4e-21
 Identities = 55/129 (42%), Positives = 69/129 (53%), Gaps = 12/129 (9%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGL---------KGERG 158
            +PG  GE G  G  G  G  G +G PG PG+ G  G +G KG  GL         +GE+G
Sbjct: 1412 IPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKG 1471

Query: 159  DQGVPGYPGKPGAQGE---PGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMG 215
            D+G+PG  G PGA+G+   PGP G  G  G  G+ G +G KG+       G+KGD G  G
Sbjct: 1472 DRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPG 1531

Query: 216  SPGLHGGPG 224
             PG  G PG
Sbjct: 1532 PPGSPGPPG 1540



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 37/78 (47%), Positives = 47/78 (60%), Gaps = 12/78 (15%)

Query: 109  PGQKGEPGETGQPGPKGEAG---NLGIPGPP---------GVVGPQGPRGYKGEKGLKGE 156
            PG++GE G+ G PG +G  G   + GIPGP          G+ GPQGP+G KG  G  G+
Sbjct: 1464 PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQ 1523

Query: 157  RGDQGVPGYPGKPGAQGE 174
            +GD G+PG PG PG  GE
Sbjct: 1524 KGDSGLPGPPGSPGPPGE 1541



 Score = 69.7 bits (169), Expect = 5e-12
 Identities = 53/143 (37%), Positives = 61/143 (42%), Gaps = 30/143 (20%)

Query: 220 HGGPGAKGEKGE--MGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKS 277
           HG  G KG+KGE  + E G + +    G  G  G  G  G  G++G  G  GD G  G  
Sbjct: 419 HGAYGEKGQKGEPAVVEPGMLVE----GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPP 474

Query: 278 GRNGLPGAKGDPGIKGEKGEL----GPPGLLGPT--------------------GPKGDI 313
           GR GLPGA G PG  G    L    G  G  GPT                    GP G +
Sbjct: 475 GRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPM 534

Query: 314 GNKGVRGPTGKKGSRGFKGSKGE 336
           G  G  GP G  GS G KG  G+
Sbjct: 535 GLTGRPGPVGGPGSSGAKGESGD 557



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 16/30 (53%), Positives = 16/30 (53%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVV 139
            G KG  G  GQ G  G  G  G PGPPG V
Sbjct: 1513 GNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1542


>gi|5803080 macrophage receptor with collagenous structure [Homo
           sapiens]
          Length = 520

 Score =  199 bits (505), Expect = 6e-51
 Identities = 120/289 (41%), Positives = 144/289 (49%), Gaps = 39/289 (13%)

Query: 84  LSPFENFTLDPADFFLNCCDCCSPVPGQKGEPGETGQPGP------KGEAGNLGIPGPPG 137
           L   +NFT +P  F +        + G KG  G  G PGP      KG  G +G  G  G
Sbjct: 131 LQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATG 190

Query: 138 VVGPQGPRGYKGEKGLKGERGDQGVPGYPGKPGAQGEPGPKGD---------------KG 182
             GPQGP G KGE GL+G +G  G  G  G PG QGE G KGD               KG
Sbjct: 191 PSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKG 250

Query: 183 NIGLGGVKGQKGSKGDT---CGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGE-------- 231
           ++GL G KG +G KGD         +G KGD G  G PGL G PGAKG++G+        
Sbjct: 251 DLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPG 310

Query: 232 ----MGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKG 287
               +G  G  G+ G  G  G  G  G  G  G  G KGSKGD+G++G+ GR G  G  G
Sbjct: 311 PPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPG 370

Query: 288 DPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
             G+KGE+G    PGL GP G  G  G KG +G  G  G +G KG KGE
Sbjct: 371 PAGVKGEQGS---PGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGE 416



 Score =  161 bits (407), Expect = 1e-39
 Identities = 90/199 (45%), Positives = 109/199 (54%), Gaps = 15/199 (7%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPG---YP 166
           G+KG  G+ G  GPKGE G  G  G  G+ G +G RG KG+ G+ G  G QG  G    P
Sbjct: 226 GEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRP 285

Query: 167 GKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAK 226
           G PG  G PG KGD+G  GL GV G  G+ G        G KG+ G+ GSPG  G PG+ 
Sbjct: 286 GPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHP------GAKGEPGSAGSPGRAGLPGSP 339

Query: 227 GEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGS------KGDSGMEGKSGRN 280
           G  G  G KG  GD G  G  G +G  G  G  G+KGE+GS      KG  G  G+ G  
Sbjct: 340 GSPGATGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQ 399

Query: 281 GLPGAKGDPGIKGEKGELG 299
           G+ G+ G+ G+KGEKGE G
Sbjct: 400 GVKGSSGEQGVKGEKGERG 418



 Score =  156 bits (394), Expect = 4e-38
 Identities = 94/204 (46%), Positives = 112/204 (54%), Gaps = 19/204 (9%)

Query: 145 RGYKGEKGLKGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCT 204
           +G +G  GL+G +G  G+PG PG PG   E G KG  G  G  G  G +G  G       
Sbjct: 147 KGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPG------V 200

Query: 205 KGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGE 264
           KGE G QG  G+PG  G   A G  G  GEKG  GD G  G  GE G KG+KG+ G+ G 
Sbjct: 201 KGEAGLQGPQGAPGKQG---ATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPG- 256

Query: 265 KGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGK 324
             SKGD GM+G +G  G PGA+G    KG+ G  GPPGL G  G KGD G  G++G  G 
Sbjct: 257 --SKGDRGMKGDAGVMGPPGAQGS---KGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGP 311

Query: 325 KGSRGFKGSKGELARVPRSAFSAG 348
            G+ G  G+KGE    P SA S G
Sbjct: 312 PGAVGHPGAKGE----PGSAGSPG 331



 Score =  140 bits (353), Expect = 3e-33
 Identities = 82/182 (45%), Positives = 96/182 (52%), Gaps = 12/182 (6%)

Query: 110 GQKGEPGETGQPGPKGEAG---NLGIPGPPGVVGPQGPRGYKGEKGLKG---ERGDQGVP 163
           G KGE G+ G PG KG+ G   + G+ GPPG  G +G  G  G  GL G    +GDQG P
Sbjct: 244 GTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQP 303

Query: 164 ---GYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGD---QGAMGSP 217
              G PG PGA G PG KG+ G+ G  G  G  GS G       KG KGD   QG  G  
Sbjct: 304 GLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRK 363

Query: 218 GLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKS 277
           G  G PG  G KGE G  G  G KG  G +G++G +G KG  G +G KG KG+ G    S
Sbjct: 364 GESGVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERGENSVS 423

Query: 278 GR 279
            R
Sbjct: 424 VR 425



 Score =  110 bits (275), Expect = 3e-24
 Identities = 67/173 (38%), Positives = 83/173 (47%), Gaps = 24/173 (13%)

Query: 183 NIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKG 242
           N G+  +KG++G+ G          +G +GAMG PG  G PG   EKG    KG MG  G
Sbjct: 140 NPGMFRIKGEQGAPG---------LQGHKGAMGMPGAPGPPGPPAEKGA---KGAMGRDG 187

Query: 243 CCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPG 302
             G SG +G  G KGE G++G +G+ G  G            A G PG +GEKG  G  G
Sbjct: 188 ATGPSGPQGPPGVKGEAGLQGPQGAPGKQG------------ATGTPGPQGEKGSKGDGG 235

Query: 303 LLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPP 355
           L+GP G  G  G KG  G  G KG RG KG  G +             +P PP
Sbjct: 236 LIGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPP 288



 Score = 97.8 bits (242), Expect = 2e-20
 Identities = 53/123 (43%), Positives = 65/123 (52%), Gaps = 15/123 (12%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
           PG  G PG  G+PG  G  G  G+PG PG  G  G +G KG+ GL+G++G +G  G PG 
Sbjct: 312 PGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGP 371

Query: 169 PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGE 228
            G +GE   +G  G  G  G  GQ             G+KGDQG  GS G  G  G KGE
Sbjct: 372 AGVKGE---QGSPGLAGPKGAPGQA------------GQKGDQGVKGSSGEQGVKGEKGE 416

Query: 229 KGE 231
           +GE
Sbjct: 417 RGE 419



 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 40/91 (43%), Positives = 50/91 (54%), Gaps = 6/91 (6%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
           +PG  G PG TG  G KG+ G  G  G  G  G  GP G KGE+G  G  G +G PG  G
Sbjct: 335 LPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQGSPGLAGPKGAPGQAG 394

Query: 168 KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGD 198
           + G QG  G  G++      GVKG+KG +G+
Sbjct: 395 QKGDQGVKGSSGEQ------GVKGEKGERGE 419


>gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]
          Length = 1714

 Score =  198 bits (503), Expect = 1e-50
 Identities = 113/261 (43%), Positives = 141/261 (54%), Gaps = 33/261 (12%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGP---------RGYKGEKGLKGERGDQ 160
            G+KGE G  G  GP+GE G +G PGPPGV GP GP         RG  G +G KG+RG +
Sbjct: 870  GEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSR 929

Query: 161  GVPGYPGKPGAQGEPGPKGDKGN------IGLGGVKGQKGSKGDTCGNCTKGEKGDQGAM 214
            G  G  G+ G QG  G KGD+G       IG  G  G++G +G        G  GD+G  
Sbjct: 930  GPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLP 989

Query: 215  GSPGLHGGPGAKGEKGEM---------GEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEK 265
            G PGL G  G  G  GEM         GE G  G+ G  GD G  G  G  GE G++GE 
Sbjct: 990  GEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEP 1049

Query: 266  GSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGP---------TGPKGDIGNK 316
            G+ G+ G++GK G  G+PG +G PG  GEKGE+G PG++GP          GP+G +G  
Sbjct: 1050 GAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIP 1109

Query: 317  GVRGPTGKKGSRGFKGSKGEL 337
            G RG  GKKG +G  G  GE+
Sbjct: 1110 GQRGRPGKKGDKGQIGPTGEV 1130



 Score =  191 bits (486), Expect = 1e-48
 Identities = 107/236 (45%), Positives = 133/236 (56%), Gaps = 15/236 (6%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           G++G  GE G+PG  G+ G +G+PGPPG+ G  GP G  G+ GL+G  G  G  G+PG  
Sbjct: 717 GEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDI 776

Query: 170 GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
           G  G+ GP+G KG +G  G  G  G KG      T+GE+G  GA G  G  G PG KG  
Sbjct: 777 GIPGQNGPEGPKGLLGNRGPPGPPGLKG------TQGEEGPIGAFGELGPRGKPGQKGYA 830

Query: 230 GEMGE---KGEMGDKGCCGDSGERGGKGQKGEGGMK---GEKGSKGDSGMEGKSGRNGLP 283
           GE G    KGE+GD+G  G  GE G  G  GE GM    GEKG +G  G  G  G  G+ 
Sbjct: 831 GEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVM 890

Query: 284 GAKGDPGIKGEKGELGPPGLL---GPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
           G  G PG+ G  G LG PG +   GP G +G  G +G RGP G  G +G +G+KGE
Sbjct: 891 GYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGE 946



 Score =  188 bits (478), Expect = 8e-48
 Identities = 110/253 (43%), Positives = 135/253 (53%), Gaps = 25/253 (9%)

Query: 108  VPGQKGEPGETGQP---GPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPG 164
            +PG+ GE GE G P   GP G +G  G+PGP G+VG  G RG  G+KG KG+ G  G  G
Sbjct: 1072 LPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVG 1131

Query: 165  YPGKPGAQGEPGPKGDK---------------GNIGLGGVKGQKGSKGDTCGNCTKGEKG 209
              G PG  G+ GPKG +               G  G+ G +G +G  G +     KGEKG
Sbjct: 1132 SRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKG 1191

Query: 210  ----DQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQK---GEGGMK 262
                D   +G PG  G PG  G++GE GE G  G KG  G  G RG  GQ+   GE G +
Sbjct: 1192 YPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQ 1251

Query: 263  GEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPT 322
            GE+G KG+ G EG  G+ G PG  G PGI G +G LGP G+ G  G  G  GN G  GP 
Sbjct: 1252 GEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPP 1311

Query: 323  GKKGSRGFKGSKG 335
            GK+G  G +G  G
Sbjct: 1312 GKQGLPGIRGGPG 1324



 Score =  187 bits (476), Expect = 1e-47
 Identities = 107/266 (40%), Positives = 140/266 (52%), Gaps = 39/266 (14%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG  G PG+ G  GPKG  GN G PGPPG+ G QG  G  G  G  G RG  G  GY G+
Sbjct: 773  PGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGE 832

Query: 169  PGAQGEPGPKGDKGNIG---------------LGGVKGQKGSKGDTCGNCTKGEKGDQGA 213
            PG +G  G  GD+GNIG               + G  G+KG +G       +GEKG  G 
Sbjct: 833  PGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGY 892

Query: 214  MGSPGLHG--------------GP----GAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQ 255
             G PG+ G              GP    G KG++G  G  G +G++G  G  GE+G +G+
Sbjct: 893  PGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGK 952

Query: 256  KGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGD------PGIKGEKGELGPPGLLGPTGP 309
            +G  G+ G+ G+ G+ G +GK G  GLPG+ GD      PG++G +G++GPPG +G  GP
Sbjct: 953  RGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGP 1012

Query: 310  KGDIGNKGVRGPTGKKGSRGFKGSKG 335
             G  G  G++G  G KG  G  GS G
Sbjct: 1013 PGTEGESGLQGEPGAKGDVGTAGSVG 1038



 Score =  184 bits (467), Expect = 2e-46
 Identities = 111/276 (40%), Positives = 143/276 (51%), Gaps = 33/276 (11%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGY---KGEKGLKGERGDQGVPGY 165
            PG  G+ GE G+PG +G  G++G+PG  G  G QGP G    +GE+GLKGERG +G  G 
Sbjct: 1209 PGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGK 1268

Query: 166  PGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGA 225
             G PG  G+PG  G +G +G  G++G  G+ G + GN   G+ G  G  G PG+ GGPG 
Sbjct: 1269 KGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGIS-GN--PGKIGPPGKQGLPGIRGGPGR 1325

Query: 226  KGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGA 285
             G  G  G  G  G  G  G  G +G KG++G  G  G +G +G  G +G  G  G PG 
Sbjct: 1326 TGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGL 1385

Query: 286  KGDPGIKGEKGELGPPGLLGPTGPKGD---------------------IGNKGVRGPTGK 324
            KG PG  G +G  G  G  GP GP+GD                     +G +G+ GPTG+
Sbjct: 1386 KGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGR 1445

Query: 325  KGSRGFKGSKGELA-RVPRSAFSAGLSKPFPPPNIP 359
             G RG KG +GE   + PR     G   P  PP  P
Sbjct: 1446 TGPRGEKGFRGETGPQGPR-----GQPGPPGPPGAP 1476



 Score =  181 bits (459), Expect = 1e-45
 Identities = 99/232 (42%), Positives = 129/232 (55%), Gaps = 6/232 (2%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQG---PRGYKGEKGLKG---ERGDQGVP 163
            G  G  GE G  G KGE G+ G  GP G++G  G    RG++G+ GL+G     GD+G+P
Sbjct: 930  GPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLP 989

Query: 164  GYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGP 223
            G PG  G QG+ GP G+ G  G  G +G+ G +G+       G  G  G  G PGL G P
Sbjct: 990  GEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEP 1049

Query: 224  GAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLP 283
            GA GE+G  G+ G  G  G  G  GE G KG+ G  G+ G  G  G +G+ G  G  G+P
Sbjct: 1050 GAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIP 1109

Query: 284  GAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
            G +G PG KG+KG++GP G +G  GP G IG  G +G  G +G+ G  G  G
Sbjct: 1110 GQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMG 1161



 Score =  181 bits (458), Expect = 2e-45
 Identities = 111/288 (38%), Positives = 147/288 (51%), Gaps = 15/288 (5%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGY---KGEKGLKGERGDQGVPG 164
           +PG++G PG  G  G  G  G  G+ GP G  GP+G +G+    GE G  G  G++G+PG
Sbjct: 580 LPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPG 639

Query: 165 YPGKPG---AQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHG 221
             GK G    QG PG  GD+G  GL G  G  G  G       +G  G  G +G  G+ G
Sbjct: 640 IRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPG 699

Query: 222 GPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNG 281
             G  G KG  G KG+ G++G  G+ GE G  G KG  G+ G  G +G SG  G++G  G
Sbjct: 700 PMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPG 759

Query: 282 LPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFK---GSKGELA 338
           L G  G PG +G  G++G PG  GP GPKG +GN+G  GP G KG++G +   G+ GEL 
Sbjct: 760 LQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELG 819

Query: 339 RVPRSAFSAGLSKPFPPPNIPIKFEKILYNDQGNYSPVTGKFNCSIPG 386
              +        +P P     +K E     DQGN   +       +PG
Sbjct: 820 PRGKPGQKGYAGEPGPE---GLKGE---VGDQGNIGKIGETGPVGLPG 861



 Score =  179 bits (455), Expect = 4e-45
 Identities = 106/256 (41%), Positives = 132/256 (51%), Gaps = 30/256 (11%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           G  G PG  G  GP G  G  GIPGP G+ G +G  G KG+KG +G  G+ G PGYPG  
Sbjct: 675 GPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDK 734

Query: 170 GAQGEPGP------------KGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSP 217
           GA G PGP             GD G  G  G  G +G  GD       G +G +G +G+ 
Sbjct: 735 GAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNR 794

Query: 218 GLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKS 277
           G  G PG KG +GE G  G  G+ G  G  G++G  G+ G  G+KGE G +G+ G  G++
Sbjct: 795 GPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGET 854

Query: 278 GRNGLPGAKGDPGIKGEKGEL------------------GPPGLLGPTGPKGDIGNKGVR 319
           G  GLPG  G  G  GEKGE                   GPPG+ GP GP G  G+ G R
Sbjct: 855 GPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGAR 914

Query: 320 GPTGKKGSRGFKGSKG 335
           GP G +G +G +GS+G
Sbjct: 915 GPPGSQGPKGQRGSRG 930



 Score =  176 bits (447), Expect = 3e-44
 Identities = 104/255 (40%), Positives = 130/255 (50%), Gaps = 15/255 (5%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGP------PGVVGPQGPRGYKG---EKGLKGERGDQ 160
           G  G PG  G PGP G+ G  GIPGP      PG+ GP+GP+G  G    + + GE+GDQ
Sbjct: 495 GPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGEKGDQ 554

Query: 161 GVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLH 220
           G+ G  G PG QG+ G KG  G  GL G +G  G  G+       G  G  G  G  G  
Sbjct: 555 GLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNI------GSPGYPGRQGLAGPE 608

Query: 221 GGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRN 280
           G PG KG +G +G  GE G  G  G+ G  G +G+KG  G +G  G  GD G  G  G  
Sbjct: 609 GNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSP 668

Query: 281 GLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARV 340
           GL G  G PG  G +G +GP G +GP G  G +G  G +G  G KG +G +G+ GEL   
Sbjct: 669 GLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEP 728

Query: 341 PRSAFSAGLSKPFPP 355
                   +  P PP
Sbjct: 729 GYPGDKGAVGLPGPP 743



 Score =  176 bits (447), Expect = 3e-44
 Identities = 108/289 (37%), Positives = 144/289 (49%), Gaps = 25/289 (8%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPG---PPGVVGPQGPRGYKGEKGLKGERGDQGVPGY 165
            PG +G PG TG  G  GE G  G+ G   PPG +G +GP G +GE GL+GE G +G  G 
Sbjct: 974  PGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGT 1033

Query: 166  PGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGA 225
             G  G  GEPG +G+ G  G  G++G+ G KG   G    GE G++G MG PG+ G  G 
Sbjct: 1034 AGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGR 1093

Query: 226  KGEKG------------EMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGM 273
             G+ G            + G  G+ GDKG  G +GE G +G  G+ G  G KG++G  G 
Sbjct: 1094 SGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGA 1153

Query: 274  EGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGN----------KGVRGPTG 323
             G  G  G  G  G PG +G +G+ GP GL GP G KG  G           +G  GP G
Sbjct: 1154 VGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVG 1213

Query: 324  KKGSRGFKGSKGELARVPRSAFSAGLSKPFPPPNIPIKFEKILYNDQGN 372
             +G RG  G++G    V          +  PP     + E+ L  ++G+
Sbjct: 1214 DQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGS 1262



 Score =  174 bits (440), Expect = 2e-43
 Identities = 102/267 (38%), Positives = 137/267 (51%), Gaps = 40/267 (14%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIP------------GPPGVVGPQGPRGYKGEKGLKGE 156
            PG++G  G+ G  G  G  G+ G+P            GPPG +G +GP G +GE GL+GE
Sbjct: 965  PGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGE 1024

Query: 157  RGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGS 216
             G +G  G  G  G  GEPG +G+ G  G  G++G+ G KG   G    GE G++G MG 
Sbjct: 1025 PGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGL 1084

Query: 217  PGL------------------------HGGPGAKGEKGEMGEKGEMGDK---GCCGDSGE 249
            PG+                         G PG KG+KG++G  GE+G +   G  G SG 
Sbjct: 1085 PGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGP 1144

Query: 250  RGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPG-LLGPTG 308
            +G +G +G  G  G  G  G+ G+ G  G  G PG  G PG KGEKG  G    +LGP G
Sbjct: 1145 KGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPG 1204

Query: 309  PKGDIGNKGVRGPTGKKGSRGFKGSKG 335
            P+G+ G  G +G  G+ G+ G+KG  G
Sbjct: 1205 PRGEPGPVGDQGERGEPGAEGYKGHVG 1231



 Score =  173 bits (438), Expect = 4e-43
 Identities = 110/262 (41%), Positives = 133/262 (50%), Gaps = 25/262 (9%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGP------------RGYKGEKGLKGE 156
           PG KG  G  G PG +G++G  G  G PG+ GP GP             G  G +G KG 
Sbjct: 731 PGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGL 790

Query: 157 RGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGS 216
            G++G PG PG  G QGE GP G  G +G  G  GQKG  G+      KGE GDQG +G 
Sbjct: 791 LGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGK 850

Query: 217 PGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGK 276
            G  G  G  GE G  G  GE G++G  G  G +G KG  G  G  G  G  G  G+ G 
Sbjct: 851 IGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGH 910

Query: 277 SGRNGLPGAKGDPGIKGEKGELGPPGLLGP---TGPKGDIGNKGVRGP------TGKKGS 327
            G  G PG++G    KG++G  GP GLLG     G KG+ G++G RGP      TG  G 
Sbjct: 911 VGARGPPGSQGP---KGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGE 967

Query: 328 RGFKGSKGELARVPRSAFSAGL 349
           RGF+G  G L  +P S    GL
Sbjct: 968 RGFQGKPG-LQGLPGSTGDRGL 988



 Score =  169 bits (428), Expect = 5e-42
 Identities = 95/230 (41%), Positives = 122/230 (53%), Gaps = 18/230 (7%)

Query: 122 GPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKPGAQGE------- 174
           GPKG+ G    PGPPG  G  GP G +G +G+ G  G+ G+PG PG  G +G+       
Sbjct: 489 GPKGDTGP---PGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQ 545

Query: 175 --PGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGA------MGSPGLHGGPGAK 226
             PG KGD+G  GL G  G +G KG        G  G+QG       +GSPG  G  G  
Sbjct: 546 PVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLA 605

Query: 227 GEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAK 286
           G +G  G KG  G  G  G++G+ G +G++G  G++G+KG KG  G  G  G  G  G  
Sbjct: 606 GPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLD 665

Query: 287 GDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
           G PG+ G  G  G PGL G  GP G IG  G+ GP G  G++G  G KG+
Sbjct: 666 GSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGD 715



 Score =  168 bits (425), Expect = 1e-41
 Identities = 105/256 (41%), Positives = 130/256 (50%), Gaps = 28/256 (10%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG +GE G  G+PG KG+ G  G  G  G  G +G  G  GE+GL+G+ G +GVPG  G 
Sbjct: 1013 PGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGL 1072

Query: 169  PGAQGEPG---------PKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGL 219
            PG  GE G         P G  G  GL G +G  G  G       KG+KG  G  G  G 
Sbjct: 1073 PGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGS 1132

Query: 220  HGGP---------GAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKG- 269
             G P         GA+G +G +G  G MG  G  G  G RG +GQ G  G+ G KG KG 
Sbjct: 1133 RGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGY 1192

Query: 270  ---DSGMEGKSGRNGLP------GAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRG 320
               DS + G  G  G P      G +G+PG +G KG +G PGL G TG +G  G  G +G
Sbjct: 1193 PGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQG 1252

Query: 321  PTGKKGSRGFKGSKGE 336
              G KG RG +G+KG+
Sbjct: 1253 EQGLKGERGSEGNKGK 1268



 Score =  166 bits (419), Expect = 6e-41
 Identities = 103/273 (37%), Positives = 126/273 (46%), Gaps = 45/273 (16%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGY--- 165
           PG++G  G  G PGPKG  G +G PG  G +GP+G RG  G +G KG +G QG PG    
Sbjct: 599 PGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGD 658

Query: 166 ------------------PGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGE 207
                             PG PG +G  GP G  G  G+ G  G  G+KG       KGE
Sbjct: 659 RGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGE 718

Query: 208 KGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGS 267
           +G  G +G PG  G  GA G  G  G +G+ G  G  GD G +G  G  G  G  G+ G 
Sbjct: 719 QGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGI 778

Query: 268 KGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGP------------------ 309
            G +G EG  G  G  G  G PG+KG +GE GP G  G  GP                  
Sbjct: 779 PGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGL 838

Query: 310 KGDIGNK------GVRGPTGKKGSRGFKGSKGE 336
           KG++G++      G  GP G  G  G  GS GE
Sbjct: 839 KGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGE 871



 Score =  132 bits (333), Expect = 5e-31
 Identities = 77/204 (37%), Positives = 102/204 (50%), Gaps = 24/204 (11%)

Query: 103  DCCSPVPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGV 162
            D  S  PG+ G PG+ G PG +G  G  G+ G PG  G +G  G  G  G++G +G+QG+
Sbjct: 1299 DGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGL 1358

Query: 163  PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
            PG   +PG QG+               +G +G++GD      +G  GD G  G PG +G 
Sbjct: 1359 PG---QPGIQGK---------------RGHRGAQGD------QGPCGDPGLKGQPGEYGV 1394

Query: 223  PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGL 282
             G  G +G  G KG  GD G  G SG +G  G +G  G  G +G  G +G  G  G  G 
Sbjct: 1395 QGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGF 1454

Query: 283  PGAKGDPGIKGEKGELGPPGLLGP 306
             G  G  G +G+ G  GPPG  GP
Sbjct: 1455 RGETGPQGPRGQPGPPGPPGAPGP 1478



 Score =  124 bits (312), Expect = 1e-28
 Identities = 81/218 (37%), Positives = 100/218 (45%), Gaps = 40/218 (18%)

Query: 157 RGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGS 216
           RG +G  G PG PG  G PGP G +G                         +G  G  G+
Sbjct: 488 RGPKGDTGPPGPPGPAGIPGPSGKRG------------------------PRGIPGPHGN 523

Query: 217 PGLHGGPGAKGEKGE---------MGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGS 267
           PGL G PG KG KG+          GEKG+ G  G  G  G +G KG KG  G+ G  G 
Sbjct: 524 PGLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGE 583

Query: 268 K------GDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGP 321
           +      G+ G  G  GR GL G +G+PG KG +G +G PG  G  GP+G+ G  G+RG 
Sbjct: 584 QGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGK 643

Query: 322 TGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPPPNIP 359
            G KG +GF G  G+         S GL     PP  P
Sbjct: 644 KGFKGRQGFPGDFGDRGPAGLDG-SPGLVGGTGPPGFP 680



 Score =  110 bits (275), Expect = 3e-24
 Identities = 62/153 (40%), Positives = 81/153 (52%), Gaps = 12/153 (7%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEK------GLKGERGDQGV 162
            PG KG  G  G PG +G  G  G+PG PG+ G +G RG +G++      GLKG+ G+ GV
Sbjct: 1335 PGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGV 1394

Query: 163  PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
             G  G  G  G  GP+GD G +G+ G KG  G +G+T      G  G +G +G  G  G 
Sbjct: 1395 QGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNT------GPLGREGIIGPTGRTGP 1448

Query: 223  PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQ 255
             G KG +GE G +G  G  G  G  G  G + Q
Sbjct: 1449 RGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQ 1481



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 34/86 (39%), Positives = 41/86 (47%), Gaps = 7/86 (8%)

Query: 273 MEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKG 332
           + G  G  G PG  G  GI G  G+ GP G+    GP G+ G  G+ GP G KG  GF  
Sbjct: 487 LRGPKGDTGPPGPPGPAGIPGPSGKRGPRGI---PGPHGNPGLPGLPGPKGPKGDPGF-- 541

Query: 333 SKGELARVPRSAFSAGLSKPFPPPNI 358
           S G+   VP      GLS    PP +
Sbjct: 542 SPGQ--PVPGEKGDQGLSGLMGPPGM 565


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score =  197 bits (502), Expect = 1e-50
 Identities = 109/258 (42%), Positives = 139/258 (53%), Gaps = 12/258 (4%)

Query: 110  GQKGEPGETGQPGPKGEAGNLG---IPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYP 166
            G KGEPG+ G+PGP GE G +G   + G PG+VG +G RG  G  G+ G +G  G PG P
Sbjct: 976  GVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMP 1035

Query: 167  GKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAK 226
            G  G  GEPGP+G  G+ G  G++G KG +G    +   GE+G +G  G PG  G PG  
Sbjct: 1036 GGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRP 1095

Query: 227  GEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAK 286
            G++G  GE+G +G +G  G  G  G  G KG  G  G +G +G  G  G+ G  G PGA 
Sbjct: 1096 GQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAV 1155

Query: 287  GDPGIKGE---KGELGP------PGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGEL 337
            G+PG+ GE   KG+LGP       GL+G  G  G  G+ G  GP G KG RG  G  GE 
Sbjct: 1156 GEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEH 1215

Query: 338  ARVPRSAFSAGLSKPFPP 355
                +         P PP
Sbjct: 1216 GEKGQEGLMGEDGPPGPP 1233



 Score =  192 bits (488), Expect = 6e-49
 Identities = 108/249 (43%), Positives = 137/249 (55%), Gaps = 21/249 (8%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG +G PG  GQ GP+G+ G +G PG PG+ G  G +G+ G  GL G +G+ G PG PG 
Sbjct: 930  PGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGP 989

Query: 169  PGAQ---------GEP---GPKGDKGNIGLGGVKGQKGSKGD---TCGNCTKGEKGDQGA 213
             G Q         GEP   G KGD+G +G  GV G KGS G      G  T GE G QG 
Sbjct: 990  VGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGP 1049

Query: 214  MGS---PGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGD 270
             GS   PG+ G  G +G +G  G  GE G +G  G  G +G  G+ G+ G+ GE+G  G 
Sbjct: 1050 PGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGS 1109

Query: 271  SGMEGKSGRNGLPGAK---GDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGS 327
             G  G  G +G PG K   G+PG +G +G +GPPG +GP GP G +G  G+ G  G KG 
Sbjct: 1110 RGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGD 1169

Query: 328  RGFKGSKGE 336
             G  G+ GE
Sbjct: 1170 LGPLGTPGE 1178



 Score =  190 bits (483), Expect = 2e-48
 Identities = 115/265 (43%), Positives = 138/265 (52%), Gaps = 37/265 (13%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGI-------PGPPGVVGPQGPRGYKGEKGLKGERGDQGV 162
            G KG  G  G PGPKGE G  G        PGPPG  GP G RG +GE G  G  G +GV
Sbjct: 1312 GHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGV 1371

Query: 163  PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
             G  GKPG QG+PG  G +G  G  G KG +G KG        G +G QG  G PG  G 
Sbjct: 1372 QGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGV 1431

Query: 223  ---------------PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGS 267
                           PG  G+ G+ GE+G+ GD G  G +G+RG  G  G  G +G  G 
Sbjct: 1432 VGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGF 1491

Query: 268  KGDSGMEGK---------SGRNGLPGAKGDPGIK---GEKGELGPP---GLLGPTGPKGD 312
            KG+SG+ G+          GR GLPG +G+PG K   G+ GE+G P   GL GP GP GD
Sbjct: 1492 KGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGD 1551

Query: 313  IGNKGVRGPTGKKGSRGFKGSKGEL 337
            IG KG++GP G  G  G +G  G L
Sbjct: 1552 IGFKGIQGPRGPPGLMGKEGIVGPL 1576



 Score =  189 bits (479), Expect = 6e-48
 Identities = 108/243 (44%), Positives = 131/243 (53%), Gaps = 18/243 (7%)

Query: 109  PGQKGEPGETGQ---------PGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGD 159
            PGQ+G  GE G          PGP G  G  G+PG PG  GPQGP G  GE G KG  G 
Sbjct: 1095 PGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGA 1154

Query: 160  QGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGL 219
             G PG PG+ G +G+ GP G  G  GL G +G+ G +GD+      G KGD+   G PG 
Sbjct: 1155 VGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDR---GDPGP 1211

Query: 220  HGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGR 279
             G  G KG++G MGE G  G  G  G  G  G  G++GE G  G KG+KG  G  G+ G 
Sbjct: 1212 DGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGV 1271

Query: 280  NGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGD------IGNKGVRGPTGKKGSRGFKGS 333
             G PG  G PG KG +G LGP G  G  G +G+       G+KG+ GP G  G +G KG 
Sbjct: 1272 PGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGE 1331

Query: 334  KGE 336
            +GE
Sbjct: 1332 QGE 1334



 Score =  188 bits (478), Expect = 8e-48
 Identities = 102/236 (43%), Positives = 132/236 (55%), Gaps = 6/236 (2%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
            +PG  G PGE G  GP G  G  G+ G  G  GP+GP G  GE+G +G +G  G  G PG
Sbjct: 1034 MPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPG 1093

Query: 168  KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSP---GLHGGPG 224
            +PG QG  G +G  G+ G  G+ G  G  G        G +G QG +G P   G  G PG
Sbjct: 1094 RPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPG 1153

Query: 225  AKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGME---GKSGRNG 281
            A GE G  GE G  GD G  G  GE+G  GQ+GE G++G+ G  G  G++   G  G +G
Sbjct: 1154 AVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDG 1213

Query: 282  LPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGEL 337
              G KG  G+ GE G  GPPG+ G  GP+G  G +G +G TG KG++G++G  GE+
Sbjct: 1214 EHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEM 1269



 Score =  186 bits (471), Expect = 5e-47
 Identities = 114/267 (42%), Positives = 139/267 (52%), Gaps = 39/267 (14%)

Query: 109  PGQKGEPGETGQPGPKGEAG---NLGIPGPPGVVGPQGPRGYKG---EKGLKGERGDQGV 162
            PG  G PGE G PGP G  G   +LG+ GP G  GP+G +G  G   E GLKG++G+QGV
Sbjct: 801  PGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGV 860

Query: 163  PGY---------------PGKPGAQGEPGPKG---DKGNIGLGGVKGQKGSKGDTCGNCT 204
            PG                PG PGA+G+PGP G   DKG+IG  G  G +G  GD      
Sbjct: 861  PGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIG---P 917

Query: 205  KGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGE 264
             G+ G +G  G PG  G PG +G+ G  G++G MG  G  G  G+ G KG  G  G+ G 
Sbjct: 918  PGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGV 977

Query: 265  KGSKGDSGMEGKSGRNGLPG---AKGDPGIKGEKGE---LGPPGLLGPTGP------KGD 312
            KG  GD G  G  G  G  G     G+PGI GEKG+   +GPPG+ GP G        G 
Sbjct: 978  KGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGG 1037

Query: 313  IGNKGVRGPTGKKGSRGFKGSKGELAR 339
            +G  G  GP G  GSRG  G +G   R
Sbjct: 1038 MGTPGEPGPQGPPGSRGPPGMRGAKGR 1064



 Score =  186 bits (471), Expect = 5e-47
 Identities = 105/245 (42%), Positives = 132/245 (53%), Gaps = 19/245 (7%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGL------KGERGDQG 161
            +PG  G PG  G PG  G  G  G  GPPG +GP+GP G  GE GL      KG+ G  G
Sbjct: 1115 IPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLG 1174

Query: 162  VPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHG 221
             PG  G  G +GEPG +GD G +G  G+KG +G  G    +   GEKG +G MG  G  G
Sbjct: 1175 TPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGP---DGEHGEKGQEGLMGEDGPPG 1231

Query: 222  GPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGE------KGSKGDSGMEG 275
             PG  G +G  G+ G+ G+KG  G  G +G +GQ GE G+ G+       G KG  G  G
Sbjct: 1232 PPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLG 1291

Query: 276  KSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKG----VRGPTGKKGSRGFK 331
             +G  G  GA+G+PG+ G  G  G  G LGP GPKG+ G +G      GP G  G RG  
Sbjct: 1292 PTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPV 1351

Query: 332  GSKGE 336
            G +G+
Sbjct: 1352 GDRGD 1356



 Score =  184 bits (466), Expect = 2e-46
 Identities = 113/272 (41%), Positives = 141/272 (51%), Gaps = 21/272 (7%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG  G PG+ G  G +G+ G  G PG PG  G  GP+G KG +G KG++G  G PG  G 
Sbjct: 1360 PGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGV 1419

Query: 169  PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQG---------AMGSPGL 219
             G QG PGP+G  G  GL G+ G  G  G       +GE+GD G           G+PG+
Sbjct: 1420 QGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGV 1479

Query: 220  HGGPGAKGE---KGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGK 276
             G PGA+G    KGE G  G++G  G  G  G  G  G +GE G KG+ G  G+ G  G 
Sbjct: 1480 AGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGM 1539

Query: 277  SGRNGLPGAKGDPGIKGEKGELGPPGLLGP---TGPKGDIGNKGVRGPTGKKGSRGFKGS 333
            +G  G  G  GD G KG +G  GPPGL+G     GP G +G  G+ GP G KGSRG  G 
Sbjct: 1540 AGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGL 1599

Query: 334  KGELARVPRS-AFSAGLSKPFPPPNIPIKFEK 364
            +G     PR      G   P  PP  PI+ ++
Sbjct: 1600 QG-----PRGPPGPRGRPGPPGPPGGPIQLQQ 1626



 Score =  182 bits (463), Expect = 4e-46
 Identities = 102/227 (44%), Positives = 122/227 (53%), Gaps = 6/227 (2%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG +G PG  GQ G  GE G+LG  G PG+ GP GP    G KGL GE G QG  G  G 
Sbjct: 1086 PGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGP---PGTKGLPGEPGPQGPQGPIGP 1142

Query: 169  PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGE 228
            P   GE GPKG  G +G  G+ G+ G KGD     T GE+G  G  G PGL G  G  G 
Sbjct: 1143 P---GEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGP 1199

Query: 229  KGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGD 288
             G  G++G+ G  G  G+ G+ G  G+ G  G  G  G +G  G  GK G  G  GAKG 
Sbjct: 1200 DGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGA 1259

Query: 289  PGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
             G +G+ GE+G PG  GP G  G  G++G  GPTG  G  G +G  G
Sbjct: 1260 KGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPG 1306



 Score =  182 bits (462), Expect = 6e-46
 Identities = 104/265 (39%), Positives = 130/265 (49%), Gaps = 18/265 (6%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGY---------------KGEKGL 153
           PG++G+PG  G PG KG  G  G+PGP G  GP+G RGY               +G  G+
Sbjct: 720 PGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGV 779

Query: 154 KGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGA 213
            G+RG  G+PG+PG  G +G PG  G+ G +GL G  G  G  GD       G  G +G 
Sbjct: 780 PGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGM 839

Query: 214 MGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGER---GGKGQKGEGGMKGEKGSKGD 270
            G  G  G PG KG+KGE G  G  GD G  GD G +   G  G +G+ G  G+ G KG 
Sbjct: 840 KGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGS 899

Query: 271 SGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGF 330
            G  G  G  G PG  G PG  G +G  G PG  G  GP+G +G +G  GP G  G+ G 
Sbjct: 900 IGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGL 959

Query: 331 KGSKGELARVPRSAFSAGLSKPFPP 355
           +G  G      R        +P  P
Sbjct: 960 EGQPGRKGFPGRPGLDGVKGEPGDP 984



 Score =  182 bits (461), Expect = 8e-46
 Identities = 107/232 (46%), Positives = 123/232 (53%), Gaps = 15/232 (6%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPG---PPGVVGPQGPRGYKGEKGLKGERGDQGVPGYP 166
            G KG  G  G PGP+G  G++G PG   P G+ G  G RG  G +G  G  GD+G  G P
Sbjct: 895  GDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPP 954

Query: 167  GKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAK 226
            G PG +G+PG KG  G  GL GVKG+ G  G        G  G+QG MG  GL G PG  
Sbjct: 955  GAPGLEGQPGRKGFPGRPGLDGVKGEPGDPG------RPGPVGEQGFMGFIGLVGEPGIV 1008

Query: 227  GEKGE---MGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLP 283
            GEKG+   MG  G  G KG  G  G  GG G  GE G +G  GS+G  GM G  GR G  
Sbjct: 1009 GEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPR 1068

Query: 284  GAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
            G  G  G +G +G  GPP   GP G  G  G +GV G  G  GSRGF G  G
Sbjct: 1069 GPDGPAGEQGSRGLKGPP---GPQGRPGRPGQQGVAGERGHLGSRGFPGIPG 1117



 Score =  181 bits (460), Expect = 1e-45
 Identities = 123/347 (35%), Positives = 154/347 (44%), Gaps = 60/347 (17%)

Query: 45  KPSSGPPPEEEET---LFTEMAEMAEPITKPSALD-SVFGTATLSPFENFTLDPADFFLN 100
           +PS   P   ++T   L    A+      +P++   S+F  A  +PF      P      
Sbjct: 574 RPSPRQPQPSQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAGSTPFPLLMGPPGPKG-- 631

Query: 101 CCDCCSP----VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQ-------------- 142
             DC  P    +PG  G PG  G  GP G  GN G+PGPPG  G +              
Sbjct: 632 --DCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGA 689

Query: 143 -------------------------GPRGYKGEKGLKGERGDQGVPGYPGK---PGAQGE 174
                                    GP G+ GE+G  G  G  G  GYPG+   PG  G+
Sbjct: 690 KGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGD 749

Query: 175 PGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGL---HGGPGAKGEKGE 231
           PGPKG +G IGL G+ G  GS G+       G++G  G  G PG+    G PG  G  GE
Sbjct: 750 PGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGE 809

Query: 232 MGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGI 291
           +G  G  G  G  GD G  G  G  G  GMKG  GS G+ G++G  G  G+PG  GDPG 
Sbjct: 810 LGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGF 869

Query: 292 KGEKGELGPPGL---LGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
           +G+KG  G PG     G  GP G +G+KG  G  G  G  GF G  G
Sbjct: 870 QGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIG 916



 Score =  179 bits (455), Expect = 4e-45
 Identities = 108/269 (40%), Positives = 135/269 (50%), Gaps = 22/269 (8%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQG---PRGYKGEKGLKGERGDQGVPGY 165
            PG  G PG+ G  G KG+ G  G+PGP G +GP+G   P G  G  GL+G+ G +G PG 
Sbjct: 912  PGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGR 971

Query: 166  PGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG--- 222
            PG  G +GEPG  G  G +G  G  G  G  G+       GEKGD+G MG PG+ G    
Sbjct: 972  PGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPG---IVGEKGDRGMMGPPGVPGPKGS 1028

Query: 223  ---PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGR 279
               PG  G  G  GE G  G  G  G  G RG KG++G  G  G  G +G  G++G  G 
Sbjct: 1029 MGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGP 1088

Query: 280  NGLPGAKGDPGIKGEKGELGP---PGLLGPTGP------KGDIGNKGVRGPTGKKGSRGF 330
             G PG  G  G+ GE+G LG    PG+ GP+GP       G+ G +G +GP G  G  G 
Sbjct: 1089 QGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGP 1148

Query: 331  KGSKGELARVPRSAFSAGLSKPFPPPNIP 359
            KG  G +   P     AG+     P   P
Sbjct: 1149 KGPPGAVGE-PGLPGEAGMKGDLGPLGTP 1176



 Score =  178 bits (452), Expect = 8e-45
 Identities = 110/263 (41%), Positives = 139/263 (52%), Gaps = 29/263 (11%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPG----------VVGPQGPRGYKGEKGLKGERGD 159
            G +GEPG  G  G KG  G LG PGP G            GP GP G +G  G +G+RG+
Sbjct: 1300 GAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGE 1359

Query: 160  QGVPGYPGKPGAQG---EPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGS 216
             G PGYPG+ G QG   +PG +G  G+ G  G  G KGSKG       +G KG QG  G+
Sbjct: 1360 PGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKG------AEGPKGKQGKAGA 1413

Query: 217  PGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGK 276
            PG  G    +G +G  G +G +G +G  G +G  G  G+ G+ G +GE+G  GD G  G 
Sbjct: 1414 PGRRG---VQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGP 1470

Query: 277  SGRNGLPGAKGDPGIKGE---KGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGS 333
            +G+ G PG  G PG +G    KGE G PG LGP G +G  G  G+ G  G+ GS+G  G 
Sbjct: 1471 AGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGD 1530

Query: 334  KGELARVPRSAFSAGLSKPFPPP 356
             GE+         AGL  P  PP
Sbjct: 1531 SGEMG----FPGMAGLFGPKGPP 1549



 Score =  177 bits (450), Expect = 1e-44
 Identities = 104/245 (42%), Positives = 130/245 (53%), Gaps = 18/245 (7%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
            G++G PG +G PG +G+ G+ G+PG PG  G  GP G  G+KG  G  G  G  G+PG  
Sbjct: 856  GEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDI 915

Query: 170  GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
            G  G+ GP+G KG  G  G+ G +G  G       +G++G  G  G+PGL G PG KG  
Sbjct: 916  GPPGDNGPEGMKGKPGARGLPGPRGQLG------PEGDEGPMGPPGAPGLEGQPGRKGFP 969

Query: 230  GEM---GEKGEMGDKGCCGDSGERGGK------GQKGEGGMKGEKGSKGDSGMEGKSGRN 280
            G     G KGE GD G  G  GE+G        G+ G  G KG++G  G  G+ G  G  
Sbjct: 970  GRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSM 1029

Query: 281  GLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVR---GPTGKKGSRGFKGSKGEL 337
            G PG  G  G  GE G  GPPG  GP G +G  G +G R   GP G++GSRG KG  G  
Sbjct: 1030 GHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQ 1089

Query: 338  ARVPR 342
             R  R
Sbjct: 1090 GRPGR 1094



 Score =  173 bits (439), Expect = 3e-43
 Identities = 106/243 (43%), Positives = 127/243 (52%), Gaps = 24/243 (9%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPPGV------VGPQGPRGYKGEKGLKGERGDQG 161
            +PG  G  GE G PG  G  G LG+PGPPGV      +G  GP GY G KG+KG  G  G
Sbjct: 788  MPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVG 847

Query: 162  VPGYPGK------PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMG 215
             PG  G       PG  G+PG +GDKG+ GL G  G +G  G        G+ GD+G++G
Sbjct: 848  EPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPL------GKVGDKGSIG 901

Query: 216  SPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEG 275
             PG  G  G  G+ G  G+ G  G KG  G  G  G +GQ G  G +G  G  G  G+EG
Sbjct: 902  FPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEG 961

Query: 276  KSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPK---GDIGNKGVRGPTGKKGSRGFKG 332
            + GR G PG    PG+ G KGE G PG  GP G +   G IG  G  G  G+KG RG  G
Sbjct: 962  QPGRKGFPGR---PGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMG 1018

Query: 333  SKG 335
              G
Sbjct: 1019 PPG 1021



 Score =  163 bits (413), Expect = 3e-40
 Identities = 100/236 (42%), Positives = 119/236 (50%), Gaps = 21/236 (8%)

Query: 119 GQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKPGAQGEPG-- 176
           G PGPKG+    G+PGPPG+ G  G  G +G +G  G  G+ G+PG PG  G +G+PG  
Sbjct: 625 GPPGPKGDC---GLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLS 681

Query: 177 ----PKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEM 232
                 G KG++GL G+ G  G  G        G  G  G  G PG  G PGAKG  G  
Sbjct: 682 PGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQ 741

Query: 233 GEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGA---KGDP 289
           G  G +GD G  G  G  G  G  G  G  GE+G  G  G  GK G  G PG    +G P
Sbjct: 742 GLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPP 801

Query: 290 GIKGEKGEL---GPPGL------LGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
           G+ G  GEL   GPPG+      LG  GP G  G KG++G  G  G  G KG KGE
Sbjct: 802 GLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGE 857



 Score =  151 bits (381), Expect = 1e-36
 Identities = 93/229 (40%), Positives = 114/229 (49%), Gaps = 30/229 (13%)

Query: 136 PGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGS 195
           P ++GP GP   KG+ GL G  G  G+PG PG  G +G PGP G+ G  G  G KGQKG 
Sbjct: 621 PLLMGPPGP---KGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGD 677

Query: 196 KGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQ 255
            G + G    G KGD G  G  G  G PG KG KG  G  G  G++G  G  G  G KG 
Sbjct: 678 PGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGY 737

Query: 256 KGEGGMKG---EKGSKGDSGMEGKSGRNGLPGAKGD---PGIKGEKGELGPP-------- 301
            G  G+ G   + G KG  G  G  G  GLPG+ G+   PG+ G++G++G P        
Sbjct: 738 PGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGE 797

Query: 302 -------------GLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGEL 337
                        GL GP G  G IG+ GV GP G  G +G KG  G +
Sbjct: 798 RGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSV 846



 Score =  135 bits (340), Expect = 8e-32
 Identities = 84/202 (41%), Positives = 99/202 (49%), Gaps = 21/202 (10%)

Query: 169 PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGE 228
           P   G PGPKGD G  G  G+ G  G  G       +G +G  G  G+PGL G PGAKG+
Sbjct: 621 PLLMGPPGPKGDCGLPGPPGLPGLPGIPG------ARGPRGPPGPYGNPGLPGPPGAKGQ 674

Query: 229 KGEM---------GEKGEMGDKGCCGDSGERGGKGQK------GEGGMKGEKGSKGDSGM 273
           KG+          G KG+MG  G  G+ G  G KG K      G  G +G+ G +G  G 
Sbjct: 675 KGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGA 734

Query: 274 EGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGS 333
           +G  GR GLPG  GDPG KG +G +G PGL G  G  G+ G  GV G  GK G  GF G 
Sbjct: 735 KGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGV 794

Query: 334 KGELARVPRSAFSAGLSKPFPP 355
            GE            L  P PP
Sbjct: 795 FGERGPPGLDGNPGELGLPGPP 816



 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 57/130 (43%), Positives = 70/130 (53%), Gaps = 15/130 (11%)

Query: 106  SPVPGQKGEPGE------TGQPGPKGEAGNLGIPGP------PGVVGPQGPRGYKGEKGL 153
            S +PGQ G PG+      TG PG +GE G+ G PG       PG+ G  GP+G  G+ G 
Sbjct: 1495 SGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGF 1554

Query: 154  KGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGA 213
            KG +G +G PG  GK   +G  GP G  G  GL G KG KGS+GD      +G  G +G 
Sbjct: 1555 KGIQGPRGPPGLMGK---EGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGR 1611

Query: 214  MGSPGLHGGP 223
             G PG  GGP
Sbjct: 1612 PGPPGPPGGP 1621


>gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [Homo
           sapiens]
          Length = 828

 Score =  197 bits (501), Expect = 2e-50
 Identities = 114/266 (42%), Positives = 136/266 (51%), Gaps = 19/266 (7%)

Query: 108 VPGQKGEPGE---------------TGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKG 152
           VPG KGE GE                G  G KG+ G +G PG  G  G +GP GY GE G
Sbjct: 302 VPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAG 361

Query: 153 LKGERGDQGVPGYPGKPGAQGEP---GPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKG 209
             GERGDQG  G PG+PG +G P   G KG KG  G  G  G  G KG   G   +G KG
Sbjct: 362 SPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKG 421

Query: 210 DQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKG 269
           + G  G PG  G PG+ G KGE G+ G  G +G  G+ G +G KG +G  G +G +G+ G
Sbjct: 422 EPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALG 481

Query: 270 DSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRG 329
           + G +G  G  G  G +GD G  G KG+ G PG   P GP+G  G KG  GP G +G RG
Sbjct: 482 EPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYP-GPRGAPGEKGEPGPRGPEGGRG 540

Query: 330 FKGSKGELARVPRSAFSAGLSKPFPP 355
             G KGE  R       A    P  P
Sbjct: 541 DFGLKGEPGRKGEKGEPADPGPPGEP 566



 Score =  191 bits (484), Expect = 2e-48
 Identities = 104/238 (43%), Positives = 124/238 (52%), Gaps = 12/238 (5%)

Query: 105 CSPVPGQKGEPGETGQPGPKGEAGNLGIPGP------PGVVGPQGPRGYKGEKGLKGERG 158
           C  +PG  G  G  GQ G KG  G  G PG       PG+ GP G  G KG  G KGE+G
Sbjct: 251 CLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKG 310

Query: 159 DQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPG 218
           + G  G  G PG  G+ G  G KG +G  G  G KG  G+      +G  G  G  GSPG
Sbjct: 311 EFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGN------RGPDGYPGEAGSPG 364

Query: 219 LHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSG 278
             G  G KG+ G  G +G  G+ G  G  G +G  G  G  G+KG KG  G  G +G+ G
Sbjct: 365 ERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPG 424

Query: 279 RNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
           R G PG KG PG  G KGE G PG  GP G  G++GNKG +G  G  G RG +G+ GE
Sbjct: 425 RRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGE 482



 Score =  190 bits (482), Expect = 3e-48
 Identities = 112/258 (43%), Positives = 128/258 (49%), Gaps = 30/258 (11%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           G KG  GE G+PG KG  G+ GI GP G  GP+G  G+KGEKG  G  G +G PG  GK 
Sbjct: 268 GAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKN 327

Query: 170 GAQGE---------PGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLH 220
           G  G+         PG KGD GN G  G  G+ GS          GE+GDQG  G PG  
Sbjct: 328 GTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGS---------PGERGDQGGKGDPGRP 378

Query: 221 GGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRN 280
           G  G  GE G  G KG  G+ G  G  G +G KG  G  G KGE G +GD G +G  G +
Sbjct: 379 GRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSD 438

Query: 281 GLPGAKGDP------------GIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSR 328
           G  G KGDP            G KG KG+ G PG  GP G  G+ G +G RG  G  G R
Sbjct: 439 GPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPR 498

Query: 329 GFKGSKGELARVPRSAFS 346
           G  G  G      R  FS
Sbjct: 499 GDSGQPGPKGDPGRPGFS 516



 Score =  189 bits (479), Expect = 6e-48
 Identities = 105/232 (45%), Positives = 125/232 (53%), Gaps = 14/232 (6%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
           PG+ G PGE G  G KG+ G  G  GPPG +G +G +GY+G  G  G  G +G  G PG 
Sbjct: 357 PGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGP 416

Query: 169 PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKG------EKGDQGAMGSPGLHGG 222
            G +GEPG +GD G  G  G  G KG KGD      +G       KG +G  G PG  G 
Sbjct: 417 RGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGP 476

Query: 223 PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGM-----KGEKGSKGDSGMEGKS 277
            GA GE G+ G +G+ GD G  GDSG+ G KG  G  G      +G  G KG+ G  G  
Sbjct: 477 QGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPE 536

Query: 278 GRNGLPGAKGDPGIKGEKGEL---GPPGLLGPTGPKGDIGNKGVRGPTGKKG 326
           G  G  G KG+PG KGEKGE    GPPG  GP GP+G  G +G  GP G  G
Sbjct: 537 GGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588



 Score =  187 bits (476), Expect = 1e-47
 Identities = 112/271 (41%), Positives = 134/271 (49%), Gaps = 44/271 (16%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGP---QGPRGYKGEKGLKGERGDQGVPGYP 166
           G+KG PG  G+ G  G+ G LG  GPPG  G    +GP GY GE G  GERGDQG  G P
Sbjct: 316 GRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDP 375

Query: 167 GKPGAQGEPGP---KGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGP 223
           G+PG +G PG    KG KG  G  G  G  G KG   G   +G KG+ G  G PG  G P
Sbjct: 376 GRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSP 435

Query: 224 GAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKG---------EKGSKGDSGME 274
           G+ G KGE G+ G  G +G  G+ G +G KG +G  G +G         ++GS+GD G  
Sbjct: 436 GSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDA 495

Query: 275 GKSGRNGLPGAKGDPGI--------KGEKGELGPPGLLGPTGPKGDIGNKGV-------- 318
           G  G +G PG KGDPG         +G  GE G PG  GP G +GD G KG         
Sbjct: 496 GPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKG 555

Query: 319 -------------RGPTGKKGSRGFKGSKGE 336
                        RGP G  G  G  G  G+
Sbjct: 556 EPADPGPPGEPGPRGPRGVPGPEGEPGPPGD 586



 Score =  186 bits (472), Expect = 4e-47
 Identities = 105/236 (44%), Positives = 129/236 (54%), Gaps = 8/236 (3%)

Query: 105 CSPVPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPG 164
           C   PG +G  G  G+ G  GE G+ G  G PG  G +GP G  G KG KG +G+ G PG
Sbjct: 344 CKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPG 403

Query: 165 YPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPG 224
            PG  GA+G PGP+G KG  G  G  G KGS G    +  KGEKGD G  G  GL G  G
Sbjct: 404 SPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPG---SDGPKGEKGDPGPEGPRGLAGEVG 460

Query: 225 AKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGS---KGDSGMEGKS--GR 279
            KG KG+ G  G  G +G  G+ G++G +G  G+ G +G+ G    KGD G  G S  G 
Sbjct: 461 NKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGP 520

Query: 280 NGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
            G PG KG+PG +G +G  G  GL G  G KG+ G     GP G+ G RG +G  G
Sbjct: 521 RGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPG 576



 Score =  186 bits (471), Expect = 5e-47
 Identities = 100/215 (46%), Positives = 122/215 (56%), Gaps = 8/215 (3%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
           PG++G PGE G  G KG  GN G PG PGV G +G  G +G KG  G RGD G  G PG 
Sbjct: 378 PGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGS 437

Query: 169 PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG---PGA 225
            G +GE G  G +G  GL G  G KG+KGD       G +G QGA+G PG  G    PG 
Sbjct: 438 DGPKGEKGDPGPEGPRGLAGEVGNKGAKGD---RGLPGPRGPQGALGEPGKQGSRGDPGD 494

Query: 226 KGEKGEMGEKGEMGDKGCCGDS--GERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLP 283
            G +G+ G+ G  GD G  G S  G RG  G+KGE G +G +G +GD G++G+ GR G  
Sbjct: 495 AGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEK 554

Query: 284 GAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGV 318
           G   DPG  GE G  GP G+ GP G  G  G+ G+
Sbjct: 555 GEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGL 589



 Score =  105 bits (263), Expect = 7e-23
 Identities = 62/151 (41%), Positives = 75/151 (49%), Gaps = 17/151 (11%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGD---------- 159
           G+KG+PG  G  G  GE GN G  G  G+ GP+GP+G  GE G +G RGD          
Sbjct: 442 GEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDS 501

Query: 160 -----QGVPGYPG--KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQG 212
                +G PG PG   PG +G PG KG+ G  G  G +G  G KG+      KGE  D G
Sbjct: 502 GQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPG 561

Query: 213 AMGSPGLHGGPGAKGEKGEMGEKGEMGDKGC 243
             G PG  G  G  G +GE G  G+ G   C
Sbjct: 562 PPGEPGPRGPRGVPGPEGEPGPPGDPGLTEC 592



 Score =  105 bits (262), Expect = 9e-23
 Identities = 66/162 (40%), Positives = 80/162 (49%), Gaps = 19/162 (11%)

Query: 193 KGSKGDTCGNCTK-------GEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCG 245
           K  K +  G C K       G  G +G  G  G  G  G  GE G+ G +G+ G +G  G
Sbjct: 236 KVMKHEAYGECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIG 295

Query: 246 DSGERGGKGQKGEGGMKGEKGSKGDSGMEGKS---------GRNGLPGAKGDPGIKGE-- 294
             G +G  G KGE G  G  G KG  G+ GK+         GR G PG KGDPG +G   
Sbjct: 296 FPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDG 355

Query: 295 -KGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
             GE G PG  G  G KGD G  G RGP G+ G++G KG +G
Sbjct: 356 YPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQG 397



 Score =  103 bits (258), Expect = 3e-22
 Identities = 56/125 (44%), Positives = 66/125 (52%)

Query: 215 GSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGME 274
           G  G  G  G KG KG MGE GE G KG  GD G  G  G  G  G+ G KG KG+ G +
Sbjct: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGAD 315

Query: 275 GKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSK 334
           G+ G  GL G  G  G KG+ G +GPPG  G  G +G  G  G  G  G++G +G KG  
Sbjct: 316 GRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDP 375

Query: 335 GELAR 339
           G   R
Sbjct: 376 GRPGR 380



 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 49/114 (42%), Positives = 59/114 (51%), Gaps = 19/114 (16%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGI--------PGPPGVVGPQGPRGYKGEKGLKGERGDQ 160
           PG  G  G++GQPGPKG+ G  G         PG  G  GP+GP G +G+ GLKGE G +
Sbjct: 492 PGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRK 551

Query: 161 GVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKG-----------DTCGNC 203
           G  G P  PG  GEPGP+G +G  G  G  G  G  G           +TCG C
Sbjct: 552 GEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCC 605



 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 51/128 (39%), Positives = 62/128 (48%), Gaps = 18/128 (14%)

Query: 230 GEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDP 289
           G  G KG  G KG  G+ GE G  GQKG    +G+ G +G  G  G  G  G  G KG+ 
Sbjct: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGR---QGDPGIEGPIGFPGPKGVPGFKGEKGEF 312

Query: 290 GIKGEK------------GELGPPGLLGPTGPKGDIGNKGVRGPTGKKGS---RGFKGSK 334
           G  G K            G+ G  G +GP G KGD GN+G  G  G+ GS   RG +G K
Sbjct: 313 GADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGK 372

Query: 335 GELARVPR 342
           G+  R  R
Sbjct: 373 GDPGRPGR 380



 Score = 29.6 bits (65), Expect = 6.3
 Identities = 20/60 (33%), Positives = 24/60 (40%), Gaps = 6/60 (10%)

Query: 305 GPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPPPNIPIKFEK 364
           GP+GPKG       RG  G KG+ G  G  G+  R         +  P P      K EK
Sbjct: 256 GPSGPKG------YRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEK 309


>gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Homo
           sapiens]
          Length = 918

 Score =  197 bits (501), Expect = 2e-50
 Identities = 114/266 (42%), Positives = 136/266 (51%), Gaps = 19/266 (7%)

Query: 108 VPGQKGEPGE---------------TGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKG 152
           VPG KGE GE                G  G KG+ G +G PG  G  G +GP GY GE G
Sbjct: 302 VPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAG 361

Query: 153 LKGERGDQGVPGYPGKPGAQGEP---GPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKG 209
             GERGDQG  G PG+PG +G P   G KG KG  G  G  G  G KG   G   +G KG
Sbjct: 362 SPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKG 421

Query: 210 DQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKG 269
           + G  G PG  G PG+ G KGE G+ G  G +G  G+ G +G KG +G  G +G +G+ G
Sbjct: 422 EPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALG 481

Query: 270 DSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRG 329
           + G +G  G  G  G +GD G  G KG+ G PG   P GP+G  G KG  GP G +G RG
Sbjct: 482 EPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYP-GPRGAPGEKGEPGPRGPEGGRG 540

Query: 330 FKGSKGELARVPRSAFSAGLSKPFPP 355
             G KGE  R       A    P  P
Sbjct: 541 DFGLKGEPGRKGEKGEPADPGPPGEP 566



 Score =  191 bits (484), Expect = 2e-48
 Identities = 104/238 (43%), Positives = 124/238 (52%), Gaps = 12/238 (5%)

Query: 105 CSPVPGQKGEPGETGQPGPKGEAGNLGIPGP------PGVVGPQGPRGYKGEKGLKGERG 158
           C  +PG  G  G  GQ G KG  G  G PG       PG+ GP G  G KG  G KGE+G
Sbjct: 251 CLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKG 310

Query: 159 DQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPG 218
           + G  G  G PG  G+ G  G KG +G  G  G KG  G+      +G  G  G  GSPG
Sbjct: 311 EFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGN------RGPDGYPGEAGSPG 364

Query: 219 LHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSG 278
             G  G KG+ G  G +G  G+ G  G  G +G  G  G  G+KG KG  G  G +G+ G
Sbjct: 365 ERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPG 424

Query: 279 RNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
           R G PG KG PG  G KGE G PG  GP G  G++GNKG +G  G  G RG +G+ GE
Sbjct: 425 RRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGE 482



 Score =  190 bits (482), Expect = 3e-48
 Identities = 112/258 (43%), Positives = 128/258 (49%), Gaps = 30/258 (11%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           G KG  GE G+PG KG  G+ GI GP G  GP+G  G+KGEKG  G  G +G PG  GK 
Sbjct: 268 GAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKN 327

Query: 170 GAQGE---------PGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLH 220
           G  G+         PG KGD GN G  G  G+ GS          GE+GDQG  G PG  
Sbjct: 328 GTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGS---------PGERGDQGGKGDPGRP 378

Query: 221 GGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRN 280
           G  G  GE G  G KG  G+ G  G  G +G KG  G  G KGE G +GD G +G  G +
Sbjct: 379 GRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSD 438

Query: 281 GLPGAKGDP------------GIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSR 328
           G  G KGDP            G KG KG+ G PG  GP G  G+ G +G RG  G  G R
Sbjct: 439 GPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPR 498

Query: 329 GFKGSKGELARVPRSAFS 346
           G  G  G      R  FS
Sbjct: 499 GDSGQPGPKGDPGRPGFS 516



 Score =  189 bits (479), Expect = 6e-48
 Identities = 105/232 (45%), Positives = 125/232 (53%), Gaps = 14/232 (6%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
           PG+ G PGE G  G KG+ G  G  GPPG +G +G +GY+G  G  G  G +G  G PG 
Sbjct: 357 PGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGP 416

Query: 169 PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKG------EKGDQGAMGSPGLHGG 222
            G +GEPG +GD G  G  G  G KG KGD      +G       KG +G  G PG  G 
Sbjct: 417 RGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGP 476

Query: 223 PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGM-----KGEKGSKGDSGMEGKS 277
            GA GE G+ G +G+ GD G  GDSG+ G KG  G  G      +G  G KG+ G  G  
Sbjct: 477 QGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPE 536

Query: 278 GRNGLPGAKGDPGIKGEKGEL---GPPGLLGPTGPKGDIGNKGVRGPTGKKG 326
           G  G  G KG+PG KGEKGE    GPPG  GP GP+G  G +G  GP G  G
Sbjct: 537 GGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588



 Score =  187 bits (476), Expect = 1e-47
 Identities = 112/271 (41%), Positives = 134/271 (49%), Gaps = 44/271 (16%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGP---QGPRGYKGEKGLKGERGDQGVPGYP 166
           G+KG PG  G+ G  G+ G LG  GPPG  G    +GP GY GE G  GERGDQG  G P
Sbjct: 316 GRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDP 375

Query: 167 GKPGAQGEPGP---KGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGP 223
           G+PG +G PG    KG KG  G  G  G  G KG   G   +G KG+ G  G PG  G P
Sbjct: 376 GRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSP 435

Query: 224 GAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKG---------EKGSKGDSGME 274
           G+ G KGE G+ G  G +G  G+ G +G KG +G  G +G         ++GS+GD G  
Sbjct: 436 GSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDA 495

Query: 275 GKSGRNGLPGAKGDPGI--------KGEKGELGPPGLLGPTGPKGDIGNKGV-------- 318
           G  G +G PG KGDPG         +G  GE G PG  GP G +GD G KG         
Sbjct: 496 GPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKG 555

Query: 319 -------------RGPTGKKGSRGFKGSKGE 336
                        RGP G  G  G  G  G+
Sbjct: 556 EPADPGPPGEPGPRGPRGVPGPEGEPGPPGD 586



 Score =  186 bits (472), Expect = 4e-47
 Identities = 105/236 (44%), Positives = 129/236 (54%), Gaps = 8/236 (3%)

Query: 105 CSPVPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPG 164
           C   PG +G  G  G+ G  GE G+ G  G PG  G +GP G  G KG KG +G+ G PG
Sbjct: 344 CKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPG 403

Query: 165 YPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPG 224
            PG  GA+G PGP+G KG  G  G  G KGS G    +  KGEKGD G  G  GL G  G
Sbjct: 404 SPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPG---SDGPKGEKGDPGPEGPRGLAGEVG 460

Query: 225 AKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGS---KGDSGMEGKS--GR 279
            KG KG+ G  G  G +G  G+ G++G +G  G+ G +G+ G    KGD G  G S  G 
Sbjct: 461 NKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGP 520

Query: 280 NGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
            G PG KG+PG +G +G  G  GL G  G KG+ G     GP G+ G RG +G  G
Sbjct: 521 RGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPG 576



 Score =  186 bits (471), Expect = 5e-47
 Identities = 100/215 (46%), Positives = 122/215 (56%), Gaps = 8/215 (3%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
           PG++G PGE G  G KG  GN G PG PGV G +G  G +G KG  G RGD G  G PG 
Sbjct: 378 PGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGS 437

Query: 169 PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG---PGA 225
            G +GE G  G +G  GL G  G KG+KGD       G +G QGA+G PG  G    PG 
Sbjct: 438 DGPKGEKGDPGPEGPRGLAGEVGNKGAKGD---RGLPGPRGPQGALGEPGKQGSRGDPGD 494

Query: 226 KGEKGEMGEKGEMGDKGCCGDS--GERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLP 283
            G +G+ G+ G  GD G  G S  G RG  G+KGE G +G +G +GD G++G+ GR G  
Sbjct: 495 AGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEK 554

Query: 284 GAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGV 318
           G   DPG  GE G  GP G+ GP G  G  G+ G+
Sbjct: 555 GEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGL 589



 Score =  105 bits (263), Expect = 7e-23
 Identities = 62/151 (41%), Positives = 75/151 (49%), Gaps = 17/151 (11%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGD---------- 159
           G+KG+PG  G  G  GE GN G  G  G+ GP+GP+G  GE G +G RGD          
Sbjct: 442 GEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDS 501

Query: 160 -----QGVPGYPG--KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQG 212
                +G PG PG   PG +G PG KG+ G  G  G +G  G KG+      KGE  D G
Sbjct: 502 GQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPG 561

Query: 213 AMGSPGLHGGPGAKGEKGEMGEKGEMGDKGC 243
             G PG  G  G  G +GE G  G+ G   C
Sbjct: 562 PPGEPGPRGPRGVPGPEGEPGPPGDPGLTEC 592



 Score =  105 bits (262), Expect = 9e-23
 Identities = 66/162 (40%), Positives = 80/162 (49%), Gaps = 19/162 (11%)

Query: 193 KGSKGDTCGNCTK-------GEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCG 245
           K  K +  G C K       G  G +G  G  G  G  G  GE G+ G +G+ G +G  G
Sbjct: 236 KVMKHEAYGECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIG 295

Query: 246 DSGERGGKGQKGEGGMKGEKGSKGDSGMEGKS---------GRNGLPGAKGDPGIKGE-- 294
             G +G  G KGE G  G  G KG  G+ GK+         GR G PG KGDPG +G   
Sbjct: 296 FPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDG 355

Query: 295 -KGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
             GE G PG  G  G KGD G  G RGP G+ G++G KG +G
Sbjct: 356 YPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQG 397



 Score =  103 bits (258), Expect = 3e-22
 Identities = 56/125 (44%), Positives = 66/125 (52%)

Query: 215 GSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGME 274
           G  G  G  G KG KG MGE GE G KG  GD G  G  G  G  G+ G KG KG+ G +
Sbjct: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGAD 315

Query: 275 GKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSK 334
           G+ G  GL G  G  G KG+ G +GPPG  G  G +G  G  G  G  G++G +G KG  
Sbjct: 316 GRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDP 375

Query: 335 GELAR 339
           G   R
Sbjct: 376 GRPGR 380



 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 49/114 (42%), Positives = 59/114 (51%), Gaps = 19/114 (16%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGI--------PGPPGVVGPQGPRGYKGEKGLKGERGDQ 160
           PG  G  G++GQPGPKG+ G  G         PG  G  GP+GP G +G+ GLKGE G +
Sbjct: 492 PGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRK 551

Query: 161 GVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKG-----------DTCGNC 203
           G  G P  PG  GEPGP+G +G  G  G  G  G  G           +TCG C
Sbjct: 552 GEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCC 605



 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 51/128 (39%), Positives = 62/128 (48%), Gaps = 18/128 (14%)

Query: 230 GEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDP 289
           G  G KG  G KG  G+ GE G  GQKG    +G+ G +G  G  G  G  G  G KG+ 
Sbjct: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGR---QGDPGIEGPIGFPGPKGVPGFKGEKGEF 312

Query: 290 GIKGEK------------GELGPPGLLGPTGPKGDIGNKGVRGPTGKKGS---RGFKGSK 334
           G  G K            G+ G  G +GP G KGD GN+G  G  G+ GS   RG +G K
Sbjct: 313 GADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGK 372

Query: 335 GELARVPR 342
           G+  R  R
Sbjct: 373 GDPGRPGR 380



 Score = 29.6 bits (65), Expect = 6.3
 Identities = 20/60 (33%), Positives = 24/60 (40%), Gaps = 6/60 (10%)

Query: 305 GPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPPPNIPIKFEK 364
           GP+GPKG       RG  G KG+ G  G  G+  R         +  P P      K EK
Sbjct: 256 GPSGPKG------YRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEK 309


>gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Homo
           sapiens]
          Length = 1019

 Score =  197 bits (501), Expect = 2e-50
 Identities = 114/266 (42%), Positives = 136/266 (51%), Gaps = 19/266 (7%)

Query: 108 VPGQKGEPGE---------------TGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKG 152
           VPG KGE GE                G  G KG+ G +G PG  G  G +GP GY GE G
Sbjct: 302 VPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAG 361

Query: 153 LKGERGDQGVPGYPGKPGAQGEP---GPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKG 209
             GERGDQG  G PG+PG +G P   G KG KG  G  G  G  G KG   G   +G KG
Sbjct: 362 SPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKG 421

Query: 210 DQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKG 269
           + G  G PG  G PG+ G KGE G+ G  G +G  G+ G +G KG +G  G +G +G+ G
Sbjct: 422 EPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALG 481

Query: 270 DSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRG 329
           + G +G  G  G  G +GD G  G KG+ G PG   P GP+G  G KG  GP G +G RG
Sbjct: 482 EPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYP-GPRGAPGEKGEPGPRGPEGGRG 540

Query: 330 FKGSKGELARVPRSAFSAGLSKPFPP 355
             G KGE  R       A    P  P
Sbjct: 541 DFGLKGEPGRKGEKGEPADPGPPGEP 566



 Score =  191 bits (484), Expect = 2e-48
 Identities = 104/238 (43%), Positives = 124/238 (52%), Gaps = 12/238 (5%)

Query: 105 CSPVPGQKGEPGETGQPGPKGEAGNLGIPGP------PGVVGPQGPRGYKGEKGLKGERG 158
           C  +PG  G  G  GQ G KG  G  G PG       PG+ GP G  G KG  G KGE+G
Sbjct: 251 CLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKG 310

Query: 159 DQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPG 218
           + G  G  G PG  G+ G  G KG +G  G  G KG  G+      +G  G  G  GSPG
Sbjct: 311 EFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGN------RGPDGYPGEAGSPG 364

Query: 219 LHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSG 278
             G  G KG+ G  G +G  G+ G  G  G +G  G  G  G+KG KG  G  G +G+ G
Sbjct: 365 ERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPG 424

Query: 279 RNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
           R G PG KG PG  G KGE G PG  GP G  G++GNKG +G  G  G RG +G+ GE
Sbjct: 425 RRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGE 482



 Score =  190 bits (482), Expect = 3e-48
 Identities = 112/258 (43%), Positives = 128/258 (49%), Gaps = 30/258 (11%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           G KG  GE G+PG KG  G+ GI GP G  GP+G  G+KGEKG  G  G +G PG  GK 
Sbjct: 268 GAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKN 327

Query: 170 GAQGE---------PGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLH 220
           G  G+         PG KGD GN G  G  G+ GS          GE+GDQG  G PG  
Sbjct: 328 GTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGS---------PGERGDQGGKGDPGRP 378

Query: 221 GGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRN 280
           G  G  GE G  G KG  G+ G  G  G +G KG  G  G KGE G +GD G +G  G +
Sbjct: 379 GRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSD 438

Query: 281 GLPGAKGDP------------GIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSR 328
           G  G KGDP            G KG KG+ G PG  GP G  G+ G +G RG  G  G R
Sbjct: 439 GPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPR 498

Query: 329 GFKGSKGELARVPRSAFS 346
           G  G  G      R  FS
Sbjct: 499 GDSGQPGPKGDPGRPGFS 516



 Score =  189 bits (479), Expect = 6e-48
 Identities = 105/232 (45%), Positives = 125/232 (53%), Gaps = 14/232 (6%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
           PG+ G PGE G  G KG+ G  G  GPPG +G +G +GY+G  G  G  G +G  G PG 
Sbjct: 357 PGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGP 416

Query: 169 PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKG------EKGDQGAMGSPGLHGG 222
            G +GEPG +GD G  G  G  G KG KGD      +G       KG +G  G PG  G 
Sbjct: 417 RGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGP 476

Query: 223 PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGM-----KGEKGSKGDSGMEGKS 277
            GA GE G+ G +G+ GD G  GDSG+ G KG  G  G      +G  G KG+ G  G  
Sbjct: 477 QGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPE 536

Query: 278 GRNGLPGAKGDPGIKGEKGEL---GPPGLLGPTGPKGDIGNKGVRGPTGKKG 326
           G  G  G KG+PG KGEKGE    GPPG  GP GP+G  G +G  GP G  G
Sbjct: 537 GGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588



 Score =  187 bits (476), Expect = 1e-47
 Identities = 112/271 (41%), Positives = 134/271 (49%), Gaps = 44/271 (16%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGP---QGPRGYKGEKGLKGERGDQGVPGYP 166
           G+KG PG  G+ G  G+ G LG  GPPG  G    +GP GY GE G  GERGDQG  G P
Sbjct: 316 GRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDP 375

Query: 167 GKPGAQGEPGP---KGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGP 223
           G+PG +G PG    KG KG  G  G  G  G KG   G   +G KG+ G  G PG  G P
Sbjct: 376 GRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSP 435

Query: 224 GAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKG---------EKGSKGDSGME 274
           G+ G KGE G+ G  G +G  G+ G +G KG +G  G +G         ++GS+GD G  
Sbjct: 436 GSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDA 495

Query: 275 GKSGRNGLPGAKGDPGI--------KGEKGELGPPGLLGPTGPKGDIGNKGV-------- 318
           G  G +G PG KGDPG         +G  GE G PG  GP G +GD G KG         
Sbjct: 496 GPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKG 555

Query: 319 -------------RGPTGKKGSRGFKGSKGE 336
                        RGP G  G  G  G  G+
Sbjct: 556 EPADPGPPGEPGPRGPRGVPGPEGEPGPPGD 586



 Score =  186 bits (472), Expect = 4e-47
 Identities = 105/236 (44%), Positives = 129/236 (54%), Gaps = 8/236 (3%)

Query: 105 CSPVPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPG 164
           C   PG +G  G  G+ G  GE G+ G  G PG  G +GP G  G KG KG +G+ G PG
Sbjct: 344 CKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPG 403

Query: 165 YPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPG 224
            PG  GA+G PGP+G KG  G  G  G KGS G    +  KGEKGD G  G  GL G  G
Sbjct: 404 SPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPG---SDGPKGEKGDPGPEGPRGLAGEVG 460

Query: 225 AKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGS---KGDSGMEGKS--GR 279
            KG KG+ G  G  G +G  G+ G++G +G  G+ G +G+ G    KGD G  G S  G 
Sbjct: 461 NKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGP 520

Query: 280 NGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
            G PG KG+PG +G +G  G  GL G  G KG+ G     GP G+ G RG +G  G
Sbjct: 521 RGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPG 576



 Score =  186 bits (471), Expect = 5e-47
 Identities = 100/215 (46%), Positives = 122/215 (56%), Gaps = 8/215 (3%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
           PG++G PGE G  G KG  GN G PG PGV G +G  G +G KG  G RGD G  G PG 
Sbjct: 378 PGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGS 437

Query: 169 PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG---PGA 225
            G +GE G  G +G  GL G  G KG+KGD       G +G QGA+G PG  G    PG 
Sbjct: 438 DGPKGEKGDPGPEGPRGLAGEVGNKGAKGD---RGLPGPRGPQGALGEPGKQGSRGDPGD 494

Query: 226 KGEKGEMGEKGEMGDKGCCGDS--GERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLP 283
            G +G+ G+ G  GD G  G S  G RG  G+KGE G +G +G +GD G++G+ GR G  
Sbjct: 495 AGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEK 554

Query: 284 GAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGV 318
           G   DPG  GE G  GP G+ GP G  G  G+ G+
Sbjct: 555 GEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGL 589



 Score =  105 bits (263), Expect = 7e-23
 Identities = 62/151 (41%), Positives = 75/151 (49%), Gaps = 17/151 (11%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGD---------- 159
           G+KG+PG  G  G  GE GN G  G  G+ GP+GP+G  GE G +G RGD          
Sbjct: 442 GEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDS 501

Query: 160 -----QGVPGYPG--KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQG 212
                +G PG PG   PG +G PG KG+ G  G  G +G  G KG+      KGE  D G
Sbjct: 502 GQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPG 561

Query: 213 AMGSPGLHGGPGAKGEKGEMGEKGEMGDKGC 243
             G PG  G  G  G +GE G  G+ G   C
Sbjct: 562 PPGEPGPRGPRGVPGPEGEPGPPGDPGLTEC 592



 Score =  105 bits (262), Expect = 9e-23
 Identities = 66/162 (40%), Positives = 80/162 (49%), Gaps = 19/162 (11%)

Query: 193 KGSKGDTCGNCTK-------GEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCG 245
           K  K +  G C K       G  G +G  G  G  G  G  GE G+ G +G+ G +G  G
Sbjct: 236 KVMKHEAYGECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIG 295

Query: 246 DSGERGGKGQKGEGGMKGEKGSKGDSGMEGKS---------GRNGLPGAKGDPGIKGE-- 294
             G +G  G KGE G  G  G KG  G+ GK+         GR G PG KGDPG +G   
Sbjct: 296 FPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDG 355

Query: 295 -KGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
             GE G PG  G  G KGD G  G RGP G+ G++G KG +G
Sbjct: 356 YPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQG 397



 Score =  103 bits (258), Expect = 3e-22
 Identities = 56/125 (44%), Positives = 66/125 (52%)

Query: 215 GSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGME 274
           G  G  G  G KG KG MGE GE G KG  GD G  G  G  G  G+ G KG KG+ G +
Sbjct: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGAD 315

Query: 275 GKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSK 334
           G+ G  GL G  G  G KG+ G +GPPG  G  G +G  G  G  G  G++G +G KG  
Sbjct: 316 GRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDP 375

Query: 335 GELAR 339
           G   R
Sbjct: 376 GRPGR 380



 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 49/114 (42%), Positives = 59/114 (51%), Gaps = 19/114 (16%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGI--------PGPPGVVGPQGPRGYKGEKGLKGERGDQ 160
           PG  G  G++GQPGPKG+ G  G         PG  G  GP+GP G +G+ GLKGE G +
Sbjct: 492 PGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRK 551

Query: 161 GVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKG-----------DTCGNC 203
           G  G P  PG  GEPGP+G +G  G  G  G  G  G           +TCG C
Sbjct: 552 GEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCC 605



 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 51/128 (39%), Positives = 62/128 (48%), Gaps = 18/128 (14%)

Query: 230 GEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDP 289
           G  G KG  G KG  G+ GE G  GQKG    +G+ G +G  G  G  G  G  G KG+ 
Sbjct: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGR---QGDPGIEGPIGFPGPKGVPGFKGEKGEF 312

Query: 290 GIKGEK------------GELGPPGLLGPTGPKGDIGNKGVRGPTGKKGS---RGFKGSK 334
           G  G K            G+ G  G +GP G KGD GN+G  G  G+ GS   RG +G K
Sbjct: 313 GADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGK 372

Query: 335 GELARVPR 342
           G+  R  R
Sbjct: 373 GDPGRPGR 380



 Score = 29.6 bits (65), Expect = 6.3
 Identities = 20/60 (33%), Positives = 24/60 (40%), Gaps = 6/60 (10%)

Query: 305 GPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPPPNIPIKFEK 364
           GP+GPKG       RG  G KG+ G  G  G+  R         +  P P      K EK
Sbjct: 256 GPSGPKG------YRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEK 309


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  196 bits (499), Expect = 3e-50
 Identities = 114/236 (48%), Positives = 134/236 (56%), Gaps = 14/236 (5%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQ--GPRGYKGEKGLKGERGDQGVPGYP 166
            PG KG  G  G  G +GE G  G PG P VVGP   GP+G KG+ G  G RG  GV G  
Sbjct: 1515 PGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGER 1574

Query: 167  GKPGA--QGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPG 224
            G PG    G+PGPKGD G+ G  G+ G+ G  GD+      GEKGD G  G PG  G  G
Sbjct: 1575 GPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSG---PPGEKGDPGRPGPPGPVGPRG 1631

Query: 225  AKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPG 284
              GE GE G++G  GD G  G +GERG +G  G  G  GEKG +GD G   + GRNG PG
Sbjct: 1632 RDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPG---EDGRNGSPG 1688

Query: 285  AKGDPGIKGEKGELGPPGLLGPTGP----KGDIGNKGVRGPTGKKGSRGFKGSKGE 336
            + G  G +GE G  GPPG L  TGP    KG+ G++G  GP G KG  G  G+ GE
Sbjct: 1689 SSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGE 1744



 Score =  194 bits (494), Expect = 1e-49
 Identities = 110/247 (44%), Positives = 131/247 (53%), Gaps = 20/247 (8%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVV----------------GPQGPRGYKGEKG 152
            PG+ G  G  G  GPKG+ G  G PGPPG +                G +GPRG KG+ G
Sbjct: 1678 PGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPG 1737

Query: 153  LKGERGDQGVPGYPGKPGAQGEPG---PKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKG 209
            L G  G++G+ G+ G PG QG+PG   P G+KG+ G  G+ G+ G  G        G  G
Sbjct: 1738 LPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNG 1797

Query: 210  DQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKG 269
              G  G PG  G PG +GE+G  G  G  G  G  G+ G+ G  G+ GE G  GE G KG
Sbjct: 1798 AAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKG 1857

Query: 270  DSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRG 329
            + G  G SGR G  G KG+ G  G  G  GPPGL GP GP G  G  GV G TG KG RG
Sbjct: 1858 EKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQ-GFPGVPGGTGPKGDRG 1916

Query: 330  FKGSKGE 336
              GSKGE
Sbjct: 1917 ETGSKGE 1923



 Score =  189 bits (480), Expect = 5e-48
 Identities = 112/261 (42%), Positives = 140/261 (53%), Gaps = 36/261 (13%)

Query: 109  PGQKGEPGETGQPGPKGEAG------------NLGIPGPPGVVGPQGPRGYKGEKG---- 152
            PGQ G  GE GQPGP GE G             LG PGPPG VGP G  G KG+KG    
Sbjct: 2406 PGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGV 2465

Query: 153  -LKGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQ 211
             L G RG++G PG  G+    G PG +G +G  G  G +G++G KGD      KG+KGD 
Sbjct: 2466 GLPGPRGERGEPGIRGE---DGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDS 2522

Query: 212  GA-MGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGD 270
               +G PG  G  G  GE+G  G  G+ G +G  GD G++G KG+ G+ G  G  G +G 
Sbjct: 2523 AVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGL 2582

Query: 271  SGMEGKSGRNGLPGAKGD------PGIKGEKGE---LGPPGLLGPTGPK------GDIGN 315
             G +G+ G  G+PG  G       PGI+GEKG+   +GP GL G  G K      G+ G+
Sbjct: 2583 LGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGD 2642

Query: 316  KGVRGPTGKKGSRGFKGSKGE 336
            KG  GP G+ G  G KG  GE
Sbjct: 2643 KGEAGPPGRPGLAGHKGEMGE 2663



 Score =  187 bits (475), Expect = 2e-47
 Identities = 106/249 (42%), Positives = 130/249 (52%), Gaps = 16/249 (6%)

Query: 107  PVPGQKGEPGETGQPGPKGEAGNLGIPGPP------GVVGPQGPRGYKGEKGLKGERGDQ 160
            P   +KGEPG+ GQ GP+G  G+ G+PG P      G  GP GP+G  G +G  GE+GD+
Sbjct: 1713 PGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDR 1772

Query: 161  GVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLH 220
            G PG  G+ G  G+PG  G  G  G  G  G  G  G       +GE+G  G  G PGL 
Sbjct: 1773 GPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLP---GLRGEQGLPGPSGPPGLP 1829

Query: 221  GGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRN 280
            G PG  G+ G  G+ GE GD G  G  GE+G  G  G  G  G KG +G  G+ G  G  
Sbjct: 1830 GKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPP 1889

Query: 281  GLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARV 340
            GLPG  G PG        G PG+ G TGPKGD G  G +G  G  G RG +G  G +  V
Sbjct: 1890 GLPGPVGPPG-------QGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNV 1942

Query: 341  PRSAFSAGL 349
             R   +AG+
Sbjct: 1943 DRLLETAGI 1951



 Score =  187 bits (475), Expect = 2e-47
 Identities = 110/253 (43%), Positives = 132/253 (52%), Gaps = 24/253 (9%)

Query: 107  PVPGQKGEPGETGQPGPKGEAGNLGIPGPPGVV---GPQGPRGYKGEKGLKGERGDQGVP 163
            P  G  G PG  G PG KG+ G  G+PG PGVV   G  GPRG  G+ G  GERG  G P
Sbjct: 2371 PGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPP 2430

Query: 164  GYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGS--------KGDTCGNCTKGEKGDQGAMG 215
            G  G PG  G PGP G  G  G  G+KG KG         +G+      +GE G  G  G
Sbjct: 2431 GREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEG 2490

Query: 216  SPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDS----------GERGGKGQKGEGGMKGEK 265
              GL G PG++GE+GE G+ G  G KG  GDS          G +G  G++G  G+ G+K
Sbjct: 2491 PRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDK 2550

Query: 266  GSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGP---PGLLGPTGPKGDIGNKGVRGPT 322
            G +GD+G  G  G  G PG KG  G+ G +G LGP   PG  G  G  G  G  GV G  
Sbjct: 2551 GPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIR 2610

Query: 323  GKKGSRGFKGSKG 335
            G+KG  GF G +G
Sbjct: 2611 GEKGDVGFMGPRG 2623



 Score =  187 bits (475), Expect = 2e-47
 Identities = 113/278 (40%), Positives = 144/278 (51%), Gaps = 47/278 (16%)

Query: 106  SPVPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGY 165
            S + G KG+PG  G PGP+GE G  GI G  G  G +GPRG  G  G +GERG++G  G 
Sbjct: 2454 SGLKGDKGDPG-VGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGS 2512

Query: 166  PGKPGAQGE-------PGPKGDKGNIG------LGGVKGQKGSKGDTCGNCTKGEKGDQG 212
             G  G +G+       PGP+G KG++G      L G KG +G  GD     +KGE GD+G
Sbjct: 2513 AGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKG 2572

Query: 213  AMGSPGLHG---------------GPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKG 257
            + G PGL G                PG+ G+ G  G +GE GD G  G  G +G +G KG
Sbjct: 2573 SAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKG 2632

Query: 258  EGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTG--------- 308
              G+ GEKG KG++G  G+ G  G  G  G+PG+ G+ G  G  GL+GP G         
Sbjct: 2633 ACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPG 2692

Query: 309  PKGDIGNKGVRG---------PTGKKGSRGFKGSKGEL 337
            PKGD G KG RG         P+G  GS G  G  G +
Sbjct: 2693 PKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSV 2730



 Score =  185 bits (470), Expect = 7e-47
 Identities = 114/290 (39%), Positives = 143/290 (49%), Gaps = 43/290 (14%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVV-----GPQGPRGYKGEKGLKGER---GD 159
            V G KGE G+ G  GP+G  G  G  GPPG+V     GP+G  G +G  GL G     GD
Sbjct: 1549 VAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGD 1608

Query: 160  QGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGL 219
             G PG  G PG  G PGP G +G  G  G KG +G  GD       G+ G++G  G+PG+
Sbjct: 1609 SGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDP---GLPGKAGERGLRGAPGV 1665

Query: 220  HGGPGAKGEKGEMGEKGEMGDKGCCGDSGERG-------------------GKGQKGEGG 260
             G  G KG++G+ GE G  G  G  G  G+RG                    KG+ G+ G
Sbjct: 1666 RGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRG 1725

Query: 261  MKGEKGSKGDSGMEGKSGRNGL------PGAKGDPGIK---GEKGELGPPGLLGPTGPKG 311
             +G +G KGD G+ G  G  G+      PG +GDPG++   GEKG+ GPPGL G +G  G
Sbjct: 1726 QEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDG 1785

Query: 312  DIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPPPNIPIK 361
              G  G  GP G  G  G  G  G    +P      GL  P  PP +P K
Sbjct: 1786 KPGAAGPSGPNGAAGKAGDPGRDG----LPGLRGEQGLPGPSGPPGLPGK 1831



 Score =  182 bits (462), Expect = 6e-46
 Identities = 122/302 (40%), Positives = 143/302 (47%), Gaps = 46/302 (15%)

Query: 72   PSALDSVFGTATLSPFENFTLDPADFFLNCCDCCSPVPGQKGEPGETGQPGPKGEAGNLG 131
            PS   +V G AT     +FT  P       C    P  GQKGEPGE G  G  G  G+ G
Sbjct: 1220 PSLDQAVSGLATALCQASFTTQPRP---EPCPVYCP-KGQKGEPGEMGLRGQVGPPGDPG 1275

Query: 132  IPGPPGVVGPQGPRG---YKGEKGL---------KGERGDQGVPGYPGKPGAQGEPGPKG 179
            +PG  G  GPQGP G    KGE+G           G  G+ G PG PG  G+ G PGP+G
Sbjct: 1276 LPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRG 1335

Query: 180  DKGNIGLGGVKGQKGSKGDTCGNCTKGE-KGDQGAMGSPGLHGGPGAKGEKGEMGEKGEM 238
            D G  G  G KG+ G+ G   G    GE  G  G  G PG  G PG +G  G+ G +G  
Sbjct: 1336 DPGERGPRGPKGEPGAPGQVIG----GEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPP 1391

Query: 239  GDKGCC--GDSGERGGKGQKGEG------------GMKGEKGSKGDSGMEGKSG-----R 279
            G  G    GD G+RG +G  G G            G+ G  G +G  G  GK G      
Sbjct: 1392 GLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSE 1451

Query: 280  NGLPGAKGDPGIKGEKGELGPPGLLGP------TGPKGDIGNKGVRGPTGKKGSRGFKGS 333
            +G PG  G PG  GE+G  GPPG +GP       GP G+ G KG RGP G  GSRG  G 
Sbjct: 1452 DGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGV 1511

Query: 334  KG 335
             G
Sbjct: 1512 AG 1513



 Score =  181 bits (458), Expect = 2e-45
 Identities = 107/251 (42%), Positives = 137/251 (54%), Gaps = 24/251 (9%)

Query: 110  GQKGEPGET----GQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGE---KGLKGERGDQGV 162
            G KG+ G++    G PGP+G  G++G  GP G+ G +GPRG  G+   KG KGE GD+G 
Sbjct: 2514 GLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGS 2573

Query: 163  PGYPG---------KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGA 213
             G PG         +PGA G PG  G  G  G+ G++G+KG  G       KGE+G +GA
Sbjct: 2574 AGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGA 2633

Query: 214  MGSPGLHGGPGAKGEKGE---MGEKGEMGDKGCCGDSGERGGK---GQKGEGGMKGEKGS 267
             G  G  G  G  G  G     G KGEMG+ G  G SG  G +   G KG+ G  G+ G 
Sbjct: 2634 CGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGP 2693

Query: 268  KGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKK-- 325
            KGD G +G+ G  G+ G  G  G  G  G  GPPG +GP GP+G  G KG RGP G++  
Sbjct: 2694 KGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVV 2753

Query: 326  GSRGFKGSKGE 336
            G+ G  G+ GE
Sbjct: 2754 GAPGVPGAPGE 2764



 Score =  180 bits (457), Expect = 2e-45
 Identities = 110/251 (43%), Positives = 131/251 (52%), Gaps = 36/251 (14%)

Query: 110  GQKGEPGETGQPG-----PKGEAGNLGIPGPPGVVGPQGPRGYKGE------------KG 152
            G KGEPGETG PG     P G  G  G PGP G+VGPQG  G  G+             G
Sbjct: 2204 GLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDG 2263

Query: 153  LKGERGDQGVPGYPGKPGAQGEPGPKGDKGN--------IGLGGVKGQKGSKGDTCGNCT 204
              G+ GD+G PG PG PG  G  GPKG+ G         +GL G KG+KG+ G   G+  
Sbjct: 2264 ASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLV 2323

Query: 205  KGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGE 264
                G+ GA G  GL   PG +GEKGE G  GE GD G  G  G  G KG KG+ G+ G 
Sbjct: 2324 ----GEPGAKGDRGL---PGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGV-GV 2375

Query: 265  KGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGK 324
             GS G  G  G  G  GLPG  G PG+ G  G+ GP G +G  GP G+   +G+ GP G+
Sbjct: 2376 PGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGE---RGLAGPPGR 2432

Query: 325  KGSRGFKGSKG 335
            +G  G  G  G
Sbjct: 2433 EGIPGPLGPPG 2443



 Score =  179 bits (453), Expect = 6e-45
 Identities = 115/309 (37%), Positives = 149/309 (48%), Gaps = 49/309 (15%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQG---PRGYKGEKGLKGERGDQGVPGY- 165
            G++G PG  G+PG  G AGN G PG PG+ G  G   PRG  GE+G +G +G+ G PG  
Sbjct: 1296 GERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQV 1355

Query: 166  -----PGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQG-------- 212
                 PG PG +G+PGP G  G  G  G  G +G  G   G   KG+KGD+G        
Sbjct: 1356 IGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPG-LPGTAMKGDKGDRGERGPPGPG 1414

Query: 213  ----AMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSK 268
                A G PGL G PG+ G +G +G  G+ G+KG      E G  G  G+ G  GE+G +
Sbjct: 1415 EGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKG----DSEDGAPGLPGQPGSPGEQGPR 1470

Query: 269  GDSGMEGKSGRNGLPGAKGDPGIKGEKGELGP------------PGLLGPTGPKGDIGNK 316
            G  G  G  G  G PG  G+ G KGE+G  GP            PG  GP GP G  G +
Sbjct: 1471 GPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQ 1530

Query: 317  GVRGPTGKKGS--------RGFKGSKGELARV-PRSAFSAGLSKPFPPPNIPIKFEKILY 367
            G +G  G+ G          G KG KG++    PR A   G+     PP + +  +    
Sbjct: 1531 GEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGA--TGVQGERGPPGLVLPGDPGPK 1588

Query: 368  NDQGNYSPV 376
             D G+  P+
Sbjct: 1589 GDPGDRGPI 1597



 Score =  177 bits (450), Expect = 1e-44
 Identities = 114/308 (37%), Positives = 149/308 (48%), Gaps = 57/308 (18%)

Query: 109  PGQKGEPGETG------------QPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGE 156
            PG KG+PG+ G              GP GE G+ G PGPPG VGP+G  G  GEKG +G 
Sbjct: 1585 PGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGP 1644

Query: 157  RGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGS 216
             GD G+PG  G+ G +G PG +G  G  G  G  G+ G  G    +  KG++G+ G  G 
Sbjct: 1645 PGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGP 1704

Query: 217  PG--LHGGPGAK-----GEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMK------- 262
            PG  +  GPGA+     G++G+ G +G  GD G  G  GERG +G +G  G +       
Sbjct: 1705 PGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRG 1764

Query: 263  --GEKGSKGDSGMEGKSGRNGLPGAKGD------------------PGIKGEK---GELG 299
              GEKG +G  G++G+SG +G PGA G                   PG++GE+   G  G
Sbjct: 1765 PAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSG 1824

Query: 300  PPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSA--------FSAGLSK 351
            PPGL G  G  G  G  G  G  G  G  G KG KG+     R           + G+  
Sbjct: 1825 PPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILG 1884

Query: 352  PFPPPNIP 359
            P  PP +P
Sbjct: 1885 PQGPPGLP 1892



 Score =  177 bits (448), Expect = 2e-44
 Identities = 110/284 (38%), Positives = 141/284 (49%), Gaps = 39/284 (13%)

Query: 107  PVPGQK-GEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLK-GERGDQGVPG 164
            PVP ++ G  G++G+ GP G+ G +G PG  G+ G +G  G +G  GL  GERG  G  G
Sbjct: 1972 PVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSG 2031

Query: 165  YPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGL----- 219
              G+PG  G PG  G  G +G  G  G++G +G+      KGE+G+QG  G PGL     
Sbjct: 2032 LAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGE------KGERGEQGRDGPPGLPGTPG 2085

Query: 220  ---------------------HGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGE 258
                                  G PG KG KGE G  G+ G KG  G  G +G +G+ G 
Sbjct: 2086 PPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGP 2145

Query: 259  GGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGP---PGLLGPTGPKGDIGN 315
             G  G  G  G+ GM G  G+ GL G +G PG  G  G+ GP   PGL GP GP+G  G 
Sbjct: 2146 RGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGL 2205

Query: 316  KGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPPPNIP 359
            KG  G TG  G RG  G  G +  +P     +GL  P   P +P
Sbjct: 2206 KGEPGETGPPG-RGLTGPTGAVG-LPGPPGPSGLVGPQGSPGLP 2247



 Score =  176 bits (445), Expect = 5e-44
 Identities = 110/281 (39%), Positives = 137/281 (48%), Gaps = 53/281 (18%)

Query: 108  VPGQKGEPGETGQPG------PKGEAGNLGIPGPPGVVGPQGPRGYKGEKG--------L 153
            +PGQ GE G+ G PG        G+ G+ G+PG PG+ GP GP+G  G  G        L
Sbjct: 2246 LPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGL 2305

Query: 154  KGERGDQGVPG-----YPGKPGAQGE---PGPKGDKGNIGLGGVKGQKGSKGDTCGNCTK 205
             G +G++G PG       G+PGA+G+   PGP+G+KG  G  G  G  G  G       K
Sbjct: 2306 PGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPK 2365

Query: 206  GEKGDQGA-----------------MGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSG 248
            G KGD G                  +G PGL G PG  G  G+ G +GEMG  G    SG
Sbjct: 2366 GFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPG---PSG 2422

Query: 249  ERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGI--KGEKGELGPPGLLGP 306
            ERG  G  G  G+ G  G  G  G  G  G +GL G KGDPG+   G +GE G PG+ G 
Sbjct: 2423 ERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGE 2482

Query: 307  TGPKGDIGNKGVRGPTGKKGSRG---------FKGSKGELA 338
             G  G  G +G+ GP G +G RG          KG KG+ A
Sbjct: 2483 DGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSA 2523



 Score =  175 bits (444), Expect = 7e-44
 Identities = 101/236 (42%), Positives = 125/236 (52%), Gaps = 31/236 (13%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQG------ 161
            +PG+KG+PG +G PGP+G  G+ G  GPPG+ G       KG+KG +GERG  G      
Sbjct: 1363 LPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGT----AMKGDKGDRGERGPPGPGEGGI 1418

Query: 162  VPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHG 221
             PG PG PG  G PGP+G  G        G+KG KGD+          + GA G PG  G
Sbjct: 1419 APGEPGLPGLPGSPGPQGPVGP------PGKKGEKGDS----------EDGAPGLPGQPG 1462

Query: 222  GPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNG 281
             PG +G +G  G  G  GD+G  G  GE G KG++G  G  G +G  G +G  G  G  G
Sbjct: 1463 SPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEG 1522

Query: 282  LPGAKGDPGIKGEKGELGPPGLLGPT-----GPKGDIGNKGVRGPTGKKGSRGFKG 332
             PG  G  G KGE G  G P ++GP      G KGD+G  G RG TG +G RG  G
Sbjct: 1523 PPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPG 1578



 Score =  174 bits (442), Expect = 1e-43
 Identities = 110/274 (40%), Positives = 135/274 (49%), Gaps = 47/274 (17%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG  G+PG  G+ GP+G  G +G  G  G  GP G  G KGE+G  G  G +G+PG  G+
Sbjct: 1455 PGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGR 1514

Query: 169  PGAQGEPGP------KGDKGNIGLGG--------VKGQKGSKGDTCGNCTKGEKGDQGAM 214
            PGA+G  GP      +G+KG  G  G        V G KG KGD      +G  G QG  
Sbjct: 1515 PGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGER 1574

Query: 215  GSPGL--HGGPGAKGEKGEMGE---------------KGEMGDKGCCGDSGERGGKGQKG 257
            G PGL   G PG KG+ G+ G                 GE GD G  G  G  G +G+ G
Sbjct: 1575 GPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDG 1634

Query: 258  EGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPP------GLLGPTGPKG 311
            E G KG++G  GD G+ GK+G  GL GA G  G  GEKG+ G P      G  G +GPKG
Sbjct: 1635 EVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKG 1694

Query: 312  DIGNKGVRGPTGK----------KGSRGFKGSKG 335
            D G  G  GP G+          KG  G +G +G
Sbjct: 1695 DRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEG 1728



 Score =  172 bits (436), Expect = 6e-43
 Identities = 109/280 (38%), Positives = 137/280 (48%), Gaps = 53/280 (18%)

Query: 106  SPVPGQKGEP------GETGQP---------GPKGEAGNLGIPGPPGVVGPQGPRGYKGE 150
            S + G +G P      GETG+P         G  G+ G+ G+PG PG+ GP GP+G  G 
Sbjct: 2235 SGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGP 2294

Query: 151  K--------GLKGERGDQGVPG-----YPGKPGAQGE---PGPKGDKGNIGLGGVKGQKG 194
                     GL G +G++G PG       G+PGA+G+   PGP+G+KG  G  G  G  G
Sbjct: 2295 TGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPG 2354

Query: 195  SKGDTCGNCTKGEKGD-----------------QGAMGSPGLHGGPGAKGEKGEMGEKGE 237
              G       KG KGD                 +G +G PGL G PG  G  G+ G +GE
Sbjct: 2355 EDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGE 2414

Query: 238  MGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGI--KGEK 295
            MG     G SGERG  G  G  G+ G  G  G  G  G  G +GL G KGDPG+   G +
Sbjct: 2415 MGQP---GPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPR 2471

Query: 296  GELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
            GE G PG+ G  G  G  G +G+ GP G +G RG KG  G
Sbjct: 2472 GERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVG 2511



 Score =  166 bits (421), Expect = 3e-41
 Identities = 100/237 (42%), Positives = 124/237 (52%), Gaps = 21/237 (8%)

Query: 106  SPVPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGY 165
            S + G+ G+PG  G PG  G  G  G P         G RG +GEKG +GE+G  G PG 
Sbjct: 2030 SGLAGEPGKPGIPGLPGRAGGVGEAGRP---------GERGERGEKGERGEQGRDGPPGL 2080

Query: 166  PGKPGAQGEPGPK--GDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGP 223
            PG PG  G PGPK   D+   GL G +G  G KG       KGE G  G  G  G  G P
Sbjct: 2081 PGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKG------AKGEPGSNGDQGPKGDRGVP 2134

Query: 224  GAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQ---KGEGGMKGEKGSKGDSGMEGKSGRN 280
            G KG++GE G +G+ G+ G  G+ G  G +G+   +G  G  G  G  GD G  G  G  
Sbjct: 2135 GIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLA 2194

Query: 281  GLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGEL 337
            G  G +G  G+KGE GE GPPG  G TGP G +G  G  GP+G  G +G  G  G++
Sbjct: 2195 GPAGPQGPSGLKGEPGETGPPG-RGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQV 2250



 Score =  166 bits (420), Expect = 4e-41
 Identities = 107/262 (40%), Positives = 130/262 (49%), Gaps = 39/262 (14%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPG-----------VVGPQGPRGYKGEKGLKGERG 158
            G+KGE GE G+ GP G  G  G PGPPG           + G QGP G KG KG  G  G
Sbjct: 2064 GEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNG 2123

Query: 159  DQGVPG---YPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKG------ 209
            DQG  G    PG  G +GEPGP+G  GN GL G +G  G +G       +G  G      
Sbjct: 2124 DQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHG 2183

Query: 210  DQGAMGSPGLHGGPGAKGEKGEMGEKGEMGD--KGCCGDSGERGGKGQKGEGGMKGEKGS 267
            D G  G+PGL G  G +G  G  GE GE G   +G  G +G  G  G  G  G+ G +GS
Sbjct: 2184 DPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGS 2243

Query: 268  KGDSGMEGKSGRNGLPGA---------KGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGV 318
             G  G  G++G+ G PG          +G PG+ G       PGL GP GPKG+ G  G 
Sbjct: 2244 PGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGS------PGLPGPVGPKGEPGPTGA 2297

Query: 319  RGP--TGKKGSRGFKGSKGELA 338
             G    G  G++G KG+ G LA
Sbjct: 2298 PGQAVVGLPGAKGEKGAPGGLA 2319



 Score =  158 bits (399), Expect = 1e-38
 Identities = 108/291 (37%), Positives = 129/291 (44%), Gaps = 72/291 (24%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGP------PGVVGPQGP-----RGYKGEKGLKGERG 158
            G  G  G  G+ GPKGE G  GI GP      PG VGP G       G  G KG +GE G
Sbjct: 1860 GDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETG 1919

Query: 159  DQGVPGYPGKPGAQGEP------------------------------------------G 176
             +G  G PG+ G +GEP                                          G
Sbjct: 1920 SKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRG 1979

Query: 177  PKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKG 236
            PKGD G  G  G +G  G  G+      KG++GD G  G PGL    G +G  G  G  G
Sbjct: 1980 PKGDSGEQGPPGKEGPIGFPGE---RGLKGDRGDPGPQGPPGL--ALGERGPPGPSGLAG 2034

Query: 237  EMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEK- 295
            E G  G  G  G  GG G+ G  G +GE+G KG+ G +G+ G  GLPG  G PG  G K 
Sbjct: 2035 EPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKV 2094

Query: 296  ----------GELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
                      GE GPPGL    G KG+ G+ G +GP G +G  G KG +GE
Sbjct: 2095 SVDEPGPGLSGEQGPPGL---KGAKGEPGSNGDQGPKGDRGVPGIKGDRGE 2142



 Score =  154 bits (390), Expect = 1e-37
 Identities = 105/295 (35%), Positives = 125/295 (42%), Gaps = 69/295 (23%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGP---PGVVGPQGPRGYKGEKGLKGERGDQGVPGYP 166
            G  G+PG  G  GP G AG  G PG    PG+ G QG  G  G  GL G+ G+ G PG  
Sbjct: 1782 GLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLN 1841

Query: 167  GKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQG-----------AMG 215
            GK G  G+PG  G KG  G  G  G++G  G        G  G QG             G
Sbjct: 1842 GKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQG 1901

Query: 216  SPGLHGGPGAKGEKGEMGEKGEMG------------------------------------ 239
             PG+ GG G KG++GE G KGE G                                    
Sbjct: 1902 FPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVE 1961

Query: 240  ---------------DKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLP- 283
                            +G  GDSGE+G  G++G  G  GE+G KGD G  G  G  GL  
Sbjct: 1962 TWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLAL 2021

Query: 284  ---GAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
               G  G  G+ GE G+ G PGL G  G  G+ G  G RG  G+KG RG +G  G
Sbjct: 2022 GERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDG 2076



 Score =  150 bits (379), Expect = 2e-36
 Identities = 85/207 (41%), Positives = 108/207 (52%), Gaps = 20/207 (9%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
            +PG  G PG+ G PG +GE G++G  GP G+ G +G +G  G  G KG++G+ G PG PG
Sbjct: 2594 IPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPG 2653

Query: 168  KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKG 227
              G +GE G  G  G  G  G +G  G KGD                   G  G PG KG
Sbjct: 2654 LAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDR------------------GFDGQPGPKG 2695

Query: 228  EKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNG--LPGA 285
            ++GE GE+G  G  G  G SG  G  G  G  G  G +G +G  G +G+ G  G  + GA
Sbjct: 2696 DQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGA 2755

Query: 286  KGDPGIKGEKGELGPPGLLGPTGPKGD 312
             G PG  GE+GE G PG  GP G KG+
Sbjct: 2756 PGVPGAPGERGEQGRPGPAGPRGEKGE 2782



 Score =  109 bits (273), Expect = 5e-24
 Identities = 61/153 (39%), Positives = 86/153 (56%), Gaps = 25/153 (16%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPG---------VVGPQGPRGY------KGEKGLK 154
            G KGE G  G+PG  G  G +G PG PG         ++GP+G RG+      KG++G K
Sbjct: 2641 GDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEK 2700

Query: 155  GERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAM 214
            GERG  G+ G+PG  G  G  GP G  G++G  G +G +G KG+      +G  G++  +
Sbjct: 2701 GERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGE------RGPPGER-VV 2753

Query: 215  GSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDS 247
            G+PG+   PGA GE+GE G  G  G +G  G++
Sbjct: 2754 GAPGV---PGAPGERGEQGRPGPAGPRGEKGEA 2783



 Score =  107 bits (267), Expect = 2e-23
 Identities = 67/181 (37%), Positives = 82/181 (45%), Gaps = 26/181 (14%)

Query: 203  CTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMK 262
            C KG+KG+ G MG  G  G PG  G  G  G  G  G  G     GERG  G  G  G  
Sbjct: 1251 CPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSP 1310

Query: 263  GEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGL------------------- 303
            G  G+ G  G  G  G  GLPG +GDPG +G +G  G PG                    
Sbjct: 1311 GRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDP 1370

Query: 304  --LGPTGPKGDIGNKGVRGPTGKKGS--RGFKGSKGELARVPRSAFSAGLSKPFPP-PNI 358
               GP GP+G +G+ G RGP G  G+  +G KG +GE  R P      G++   P  P +
Sbjct: 1371 GPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGE--RGPPGPGEGGIAPGEPGLPGL 1428

Query: 359  P 359
            P
Sbjct: 1429 P 1429



 Score = 89.4 bits (220), Expect = 7e-18
 Identities = 43/85 (50%), Positives = 55/85 (64%), Gaps = 8/85 (9%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQ-----GVPG 164
            G++G PG  G PGP G  G+ G PGPPG VGP+GP G +G+KG +G  G++     GVPG
Sbjct: 2701 GERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPG 2760

Query: 165  YPGKPGAQGEPGP---KGDKGNIGL 186
             PG+ G QG PGP   +G+KG   L
Sbjct: 2761 APGERGEQGRPGPAGPRGEKGEAAL 2785



 Score = 30.8 bits (68), Expect = 2.8
 Identities = 11/24 (45%), Positives = 15/24 (62%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGI 132
            PG++GE G  G  GP+GE G   +
Sbjct: 2762 PGERGEQGRPGPAGPRGEKGEAAL 2785


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score =  196 bits (498), Expect = 4e-50
 Identities = 118/270 (43%), Positives = 141/270 (52%), Gaps = 24/270 (8%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPG------VVGPQGPRGYKGEKGLKGERGDQGV 162
            PG  G PG  G PGPKG  G +G+PG PG      + GPQG  G  G+KG KGE+G  G 
Sbjct: 995  PGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGP 1054

Query: 163  PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
            PG  G PG +GE G +G  G  G  G KG+KGS G      + G KG  G++G PG  G 
Sbjct: 1055 PGI-GIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGL 1113

Query: 223  PGAKGEK------GEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGK 276
            PG KG+K      G  G KGE G  G  G +G  G KG+ G  G+ G  G KG+ G+ G+
Sbjct: 1114 PGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGR 1173

Query: 277  SGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
             G  G PGAKGD   KG KGE+G PGL G  G  G  G +G  GP G +G  G  GS G 
Sbjct: 1174 -GFPGFPGAKGD---KGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGH 1229

Query: 337  LARVPRSAFS-------AGLSKPFPPPNIP 359
                P+            GL  P  PP +P
Sbjct: 1230 ATEGPKGDRGPQGQPGLPGLPGPMGPPGLP 1259



 Score =  188 bits (478), Expect = 8e-48
 Identities = 109/251 (43%), Positives = 136/251 (54%), Gaps = 23/251 (9%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
            +PGQ+G PG  G PG KGE G +G PG PG  GP G        GL GE+GD G   +PG
Sbjct: 862  LPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGA------PGLPGEKGDHG---FPG 912

Query: 168  KPGAQGEPGPKGDKGNIGLGGVKGQ---------KGSKGDTCGNCTKGEKGDQGAMGSPG 218
              G +G+PG KGDKG++GL G  G          KG KGD       G  G++G+ G PG
Sbjct: 913  SSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPG 972

Query: 219  LHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSG 278
              G PG  G+ G+ G+ G  GD G  G  G  G  G KG  G  G  G+ G+ G+ G  G
Sbjct: 973  TPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPG 1032

Query: 279  RNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELA 338
              G PG  GD G KGEKG+ GPPG +G  G +G+ G++G+ G  G  G +G KGS G   
Sbjct: 1033 PQGSPGLPGDKGAKGEKGQAGPPG-IGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIG--- 1088

Query: 339  RVPRSAFSAGL 349
             +P    S GL
Sbjct: 1089 -IPGMPGSPGL 1098



 Score =  187 bits (475), Expect = 2e-47
 Identities = 123/334 (36%), Positives = 157/334 (47%), Gaps = 71/334 (21%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPP---GVVGPQGPRGYKGE-------------- 150
            +PG KG PG  G PG  GE G++G+PG P   G +GP G +G +GE              
Sbjct: 738  LPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPG 797

Query: 151  ------KGLKGERGDQGVPGYPGKPGAQGE-----------PGPKGDKGNIGLGGVKGQK 193
                   G +G  G QG PG  G PG +GE           PGPKGDKG  GL G+ GQ 
Sbjct: 798  VPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQS 857

Query: 194  ------------------GSKGDTCGNCTKGEKGDQGAMGSPGL------HGGPGAKGEK 229
                              GSKG+     T G+ G  G +G+PGL      HG PG+ G +
Sbjct: 858  GLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPR 917

Query: 230  GEMGEKGEMGDKGCCGD------------SGERGGKGQKGEGGMKGEKGSKGDSGMEGKS 277
            G+ G KG+ GD G  G              G++G +G+KG+ G  GEKGS+GD G  G  
Sbjct: 918  GDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVP 977

Query: 278  GRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGEL 337
            G++G  G  G PG KG+ G  G PG  G  GPKG +G  G+ G  G+KG  G  G +G  
Sbjct: 978  GKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGS- 1036

Query: 338  ARVPRSAFSAGLSKPFPPPNIPIKFEKILYNDQG 371
              +P    + G      PP I I   +    DQG
Sbjct: 1037 PGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQG 1070



 Score =  184 bits (468), Expect = 1e-46
 Identities = 105/233 (45%), Positives = 132/233 (56%), Gaps = 6/233 (2%)

Query: 108  VPGQKGE---PGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPG 164
            +PG+KG+   PG  G PG KGEAG  G PGP G  G +G  G  G  G  GE+G+ G+PG
Sbjct: 1113 LPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPG 1172

Query: 165  --YPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
              +PG PGA+G+ G KG+ G  GL G  G  GSKG+       G +G  G  GSPG H  
Sbjct: 1173 RGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPG-HAT 1231

Query: 223  PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGL 282
             G KG++G  G+ G  G  G  G  G  G  G KG+ G  G  G+ G  G +G  G  G+
Sbjct: 1232 EGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGM 1291

Query: 283  PGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
            PG  G PGI G KG++GPPG+ G  GPKG  G +G++G  G +G  G KG  G
Sbjct: 1292 PGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPG 1344



 Score =  184 bits (466), Expect = 2e-46
 Identities = 113/261 (43%), Positives = 131/261 (50%), Gaps = 33/261 (12%)

Query: 108 VPGQKGEPGETGQPG---PKGEAGNLGIPGPPGVVGPQGPRGYKGEKG------------ 152
           +PGQ G PG  G PG    KGE G LG PG PG  G  GP G  G KG            
Sbjct: 110 IPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGM 169

Query: 153 -LKGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDT-----CGNCTKG 206
            LKGERG  G+PG PG PG  G  GP G  G  G  G  G  G  G+           KG
Sbjct: 170 LLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKG 229

Query: 207 EKGDQGAMGSPGLHGGP--------GAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGE 258
           +KGDQG  G PG+ G            KGEKG+ GE G  G  G  G+ GE G  G +G+
Sbjct: 230 DKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGV-GEKGEPGKPGPRGK 288

Query: 259 GGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLL---GPTGPKGDIGN 315
            G  G+KG KG  G  G+ G  GL G +G  G KGE G  GPPG++   GP G KG+ G 
Sbjct: 289 PGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGY 348

Query: 316 KGVRGPTGKKGSRGFKGSKGE 336
            G  GP G+ G +GF G  G+
Sbjct: 349 PGTPGPRGEPGPKGFPGLPGQ 369



 Score =  183 bits (465), Expect = 3e-46
 Identities = 112/276 (40%), Positives = 140/276 (50%), Gaps = 30/276 (10%)

Query: 108  VPGQKGEPGETG--QPGPKGEAGNLGIPGP------PGVVGPQGPRGYKGEKGLKGERGD 159
            + G+KG PG  G   PGPKG+ G  G+PG       PG+ G QG  G  G  G KGE G 
Sbjct: 824  IKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGV 883

Query: 160  QGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPG- 218
             G PG PG PG  G PG  G+KG+ G  G  G +G  G       KG+KGD G  G PG 
Sbjct: 884  MGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPG------LKGDKGDVGLPGKPGS 937

Query: 219  -----LHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGM 273
                 +    G KG++GE G+ G +G+KG  GD G  G  G+ G+ G  G+ G KGD G+
Sbjct: 938  MDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGI 997

Query: 274  EGKSGRNGLPGAKGD---PGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGS--- 327
             G  G  GLPG KG     G+ G  GE G PG+ GP G  G  G+KG +G  G+ G    
Sbjct: 998  SGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGI 1057

Query: 328  --RGFKGSKGE--LARVPRSAFSAGLSKPFPPPNIP 359
               G +G KG+  +A  P S    G       P +P
Sbjct: 1058 GIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMP 1093



 Score =  182 bits (463), Expect = 4e-46
 Identities = 117/295 (39%), Positives = 144/295 (48%), Gaps = 50/295 (16%)

Query: 108  VPGQKGEPGETG------QPGPKGEAGNLGIPG---PPGVVGPQGPRGYKGEKGLKGERG 158
            +PG +GE G+ G       PG KGE G++GIPG    PG+ G  G  GY G  GL GE+G
Sbjct: 1059 IPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKG 1118

Query: 159  DQGVPGYPGKPGAQGEPG---------PKGDKGNIGLGGVKGQKGSKGDTC--------G 201
            D+G+PG  G PG +GE G         P G KG  G  G+ G  G KG+           
Sbjct: 1119 DKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGF 1178

Query: 202  NCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKG-----------CCGDSGER 250
               KG+KG +G +G PGL G PG  G KGE G  G  G +G             G  G+R
Sbjct: 1179 PGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDR 1238

Query: 251  GGKGQKGEGGMKGEKGS---------KGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPP 301
            G +GQ G  G+ G  G          KGD G  G  G  G+PG KGDPG +G  G  G P
Sbjct: 1239 GPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSP 1298

Query: 302  GLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPPP 356
            G+ G  G  G  G  G +GP G  G +G KG +G+   VP    + GL  P  PP
Sbjct: 1299 GITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQG-VPG---AKGLPGPPGPP 1349



 Score =  179 bits (454), Expect = 5e-45
 Identities = 118/302 (39%), Positives = 140/302 (46%), Gaps = 56/302 (18%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPG--VVGPQGPRGYKGEKGLKGERG--------- 158
           G  G PG  G+PGPKG  G  G PGPPG  V G  G  G+ GE+G KG+RG         
Sbjct: 347 GYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGP 406

Query: 159 --DQGVPGYPGKPGAQGEPG-----------PKGDKGNIGLGGVKG------QKGSKGDT 199
               G+PG PG PG  G+PG           P GD+G  G+ G  G      +KG KG++
Sbjct: 407 SGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGES 466

Query: 200 CGNCT----KGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKG------EMGDKGCCGDSGE 249
           C  C     +G  G QG  G  G  G PGAKG++G  G  G        G  G  G  G 
Sbjct: 467 CLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGA 526

Query: 250 RGG----------KGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELG 299
           +G           KG KG+ G  G+ G  G +G  G+ G  GLPG KG PG  G KGE G
Sbjct: 527 KGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERG 586

Query: 300 PPGLLGPTGPKGDIG-----NKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFP 354
           PPG +G  G +GD G       G  GP G KG  GF G  G    +P      G   P P
Sbjct: 587 PPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGS-PGLPGPKGEPGKIVPLP 645

Query: 355 PP 356
            P
Sbjct: 646 GP 647



 Score =  178 bits (451), Expect = 1e-44
 Identities = 116/262 (44%), Positives = 132/262 (50%), Gaps = 38/262 (14%)

Query: 109 PGQKGEPGETGQ-----PGPKGEAGNLGIPGPPGVVGP-----QGPRGYKGEKGLKGERG 158
           PG  G PGE GQ      GPKG+ G+ G+ GPPGV G      +G    KGEKG KGE G
Sbjct: 208 PGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPG 267

Query: 159 DQGVPGY-----PGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGA 213
            QG+PG      PGKPG +G+PG  GDKG  G  G  G+ G  G       +GEKG+ G 
Sbjct: 268 FQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGP 327

Query: 214 MGSPGLHGGPGAKGEKGEM------GEKGEMGDKGCCGDSGERGG-----KGQKGEGGMK 262
            G PG+  G G  GEKGE       G +GE G KG  G  G+ G       GQ G  G  
Sbjct: 328 PGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFP 387

Query: 263 GEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPT--------GPKGDIG 314
           GE+G KGD G  G S    LPG  G  G+ G  G  GPPG  G T        GP GD G
Sbjct: 388 GERGEKGDRGFPGTS----LPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQG 443

Query: 315 NKGVRGPTGKKGSRGFKGSKGE 336
             G+ G  G  G  G KG KGE
Sbjct: 444 PPGIPGQPGFIGEIGEKGQKGE 465



 Score =  177 bits (450), Expect = 1e-44
 Identities = 118/288 (40%), Positives = 134/288 (46%), Gaps = 39/288 (13%)

Query: 107 PVPGQKGEPGETGQPGPKGE-----------AGNLGIPGPPGVVGPQGPRGYKGE--KGL 153
           PVPGQ G PG  G+ G KG+           +G  G+PGPPG  GP G  GY     +  
Sbjct: 376 PVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQ 435

Query: 154 KGERGDQGVPGYPGKPGAQGEPGPKGDKGNI-------------------GLGGVKGQKG 194
            G  GDQG PG PG+PG  GE G KG KG                     G  G  GQ G
Sbjct: 436 PGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPG 495

Query: 195 SKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGE----MGEKGEMGDKGCCGDSGER 250
           +KGD       G  G  G  G+PGL G PGAKGE GE    +  KG+ GD G  G  G  
Sbjct: 496 AKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMT 555

Query: 251 GGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPK 310
           G  G  G  G  G  G KG  G  G  G  G PG  G PG +G+ G  GPPG  GP GP 
Sbjct: 556 GRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGY-GPAGPI 614

Query: 311 GDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGL--SKPFPPP 356
           GD G  G  G  G  G  G KG  G++  +P    + GL  S  FP P
Sbjct: 615 GDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGP 662



 Score =  175 bits (444), Expect = 7e-44
 Identities = 115/303 (37%), Positives = 141/303 (46%), Gaps = 56/303 (18%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVV------GPQGPRGYKGEKGLKGERGDQGV 162
           PG+ G PG  G+ GP+GE G  G PGPPG+V      G +G RGY G  G +GE G +G 
Sbjct: 304 PGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGF 363

Query: 163 PGYPGKP-----------GAQGEPGPKGDKGNIGLGGVK-----------------GQKG 194
           PG PG+P           GA G PG +G+KG+ G  G                   G  G
Sbjct: 364 PGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPG 423

Query: 195 SKGDTCG--NCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGE----------KGEMGDKG 242
             G T G   C  G  GDQG  G PG  G  G  GEKG+ GE          +G  G +G
Sbjct: 424 QPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQG 483

Query: 243 CCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPG-------IKGEK 295
             G+ G  G  G KG+ G+ G  G  G  G +G  G  G PGAKG+PG       +KG+K
Sbjct: 484 PPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDK 543

Query: 296 GE---LGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKP 352
           G+    G PG+ G  G  G  G+ G+ GP G  GS G KG +G    V           P
Sbjct: 544 GDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPP 603

Query: 353 FPP 355
            PP
Sbjct: 604 GPP 606



 Score =  173 bits (438), Expect = 4e-43
 Identities = 109/267 (40%), Positives = 127/267 (47%), Gaps = 41/267 (15%)

Query: 110  GQKGEPGETGQ-----PGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPG 164
            G+KGEPG  G+     PG KG+ G+ G  G PG+ G  G  G KGE+G  G  G QG PG
Sbjct: 1163 GEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPG 1222

Query: 165  YPG-----------------KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGE 207
             PG                 +PG  G PGP G  G  G+ GVKG KG+ G        G 
Sbjct: 1223 LPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGP 1282

Query: 208  KGDQGAMGSPGLHGGPGAKGEKGEMGE---------KGEMGDKGCCGDSGERGGKGQKGE 258
            KGD G  G PG+ G PG  G KG+MG          KG  G +G  GD G++G  G KG 
Sbjct: 1283 KGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGL 1342

Query: 259  GG----------MKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTG 308
             G          +KGE G  G  G  G  G  GLPG KG  G+ G  G  GPPG+ G  G
Sbjct: 1343 PGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDG 1402

Query: 309  PKGDIGNKGVRGPTGKKGSRGFKGSKG 335
              G  G  G  GPTG +G  G  G  G
Sbjct: 1403 APGQKGEMGPAGPTGPRGFPGPPGPDG 1429



 Score =  172 bits (436), Expect = 6e-43
 Identities = 105/256 (41%), Positives = 127/256 (49%), Gaps = 27/256 (10%)

Query: 107  PVPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGY- 165
            P  G  G PG  G  G KGE G  G+ G PG+ G +G +G+ G  G +G+ G  G PG+ 
Sbjct: 1171 PGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHA 1230

Query: 166  ----------PGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMG 215
                       G+PG  G PGP G  G  G+ GVKG KG+ G        G KGD G  G
Sbjct: 1231 TEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQG 1290

Query: 216  SPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEG 275
             PG+ G PG  G KG+MG  G  G +G  G  G +G KG +G+ G+ G KG  G  G  G
Sbjct: 1291 MPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPG 1350

Query: 276  K----SGRNGLPGAKGDPGIK------GEKGELGPPGLLGPTGP------KGDIGNKGVR 319
                  G  GLPG +G PG+K      G KG+ G  GL+G  GP       G  G KG  
Sbjct: 1351 PYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEM 1410

Query: 320  GPTGKKGSRGFKGSKG 335
            GP G  G RGF G  G
Sbjct: 1411 GPAGPTGPRGFPGPPG 1426



 Score =  172 bits (435), Expect = 8e-43
 Identities = 111/299 (37%), Positives = 140/299 (46%), Gaps = 52/299 (17%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGP--------RGYKGEKGLKGERGD 159
            +PG KGE G  G PGP G AG  G PG  G+ G  G         RG+ G  G KG++G 
Sbjct: 1128 IPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGS 1187

Query: 160  QGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGL 219
            +G  G+PG  G+ G PG KG++G +G  G +GQ G  G   G+ T+G KGD+G  G PGL
Sbjct: 1188 KGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSP-GHATEGPKGDRGPQGQPGL 1246

Query: 220  HGGPGAKGEKGEMGEKGEMGDKG---------CCGDSGERGGKGQKGEGGMKGEKGSKGD 270
             G PG  G  G  G  G  GDKG           G  G+ G +G  G GG  G  GSKGD
Sbjct: 1247 PGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGD 1306

Query: 271  ------------------SGMEGKSGRNGLPGAKG----------------DPGIKGEKG 296
                               G++G  G  G+PGAKG                +PG+ G +G
Sbjct: 1307 MGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEG 1366

Query: 297  ELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPP 355
              G  GL G  GPKG  G  G+ G  G  G  GF G+ G+   +  +  +     P PP
Sbjct: 1367 PPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPP 1425



 Score =  170 bits (431), Expect = 2e-42
 Identities = 124/344 (36%), Positives = 147/344 (42%), Gaps = 90/344 (26%)

Query: 102 CDCCSPVPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGL---KGERG 158
           CDC     G KG+ GE G PG +G  G  G+ GP G  GP G +G  GE GL   KG RG
Sbjct: 39  CDC----HGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRG 94

Query: 159 DQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSK---------------------- 196
             G  GYPG PG  G PG  G  G  G+ G  G KG +                      
Sbjct: 95  PPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPG 154

Query: 197 ---------GDTCGNCTKGEKGD---------------QGAMGSPGLHGGPGAKGEKGEM 232
                    G   G   KGE+G                QG +G PG  G PG  G  G  
Sbjct: 155 MKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPP 214

Query: 233 GEKGEM--------GDKGCCGDSGERGGKGQ-----KGEGGMKGEKGSKGDSGME----- 274
           GEKG+M        GDKG  G SG  G  GQ     KG+   KGEKG KG+ G +     
Sbjct: 215 GEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGV 274

Query: 275 GKSGRNGLPGAKGDPGIKGEKGELGP---------PGLLGPTGPKGDIGNKGV------- 318
           G+ G  G PG +G PG  G+KGE G          PGL+G  GP+G+ G  G        
Sbjct: 275 GEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIV 334

Query: 319 --RGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPPPNIPI 360
              GP G+KG RG+ G+ G         F  GL     PP +P+
Sbjct: 335 IGTGPLGEKGERGYPGTPGPRGEPGPKGF-PGLPGQPGPPGLPV 377



 Score =  169 bits (427), Expect = 7e-42
 Identities = 102/234 (43%), Positives = 126/234 (53%), Gaps = 18/234 (7%)

Query: 109  PGQKGEPGETGQPG-----PKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVP 163
            PG +G+PG  G PG     PKG+ G  G PG PG+ GP GP G  G  G+KG++G+ G P
Sbjct: 1215 PGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWP 1274

Query: 164  GYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGP 223
            G PG PG +G+P   G +G  G+GG  G  GSKGD       G  G QG  G PGL G  
Sbjct: 1275 GAPGVPGPKGDP---GFQGMPGIGGSPGITGSKGDM---GPPGVPGFQGPKGLPGLQGIK 1328

Query: 224  GAKGEKGEMGEKGEMGDKGCCGD----SGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGR 279
            G +G++G  G KG  G  G  G      GE G  G +G  G+KG +G  G  G +G +G 
Sbjct: 1329 GDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGL 1388

Query: 280  NGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGS 333
             G+PG  G PG  G  G+ G  G  GPTGP+   G  G  GP G  GS G  G+
Sbjct: 1389 VGIPGPPGIPGFDGAPGQKGEMGPAGPTGPR---GFPGPPGPDGLPGSMGPPGT 1439



 Score =  167 bits (423), Expect = 2e-41
 Identities = 107/260 (41%), Positives = 131/260 (50%), Gaps = 37/260 (14%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
           +PG KG PG  G  G +G  G +G PG  G  GP GP GY    G  G  GD+G  G+PG
Sbjct: 569 LPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGY----GPAGPIGDKGQAGFPG 624

Query: 168 KPGAQGEPGPKGDKGNI----------GLGGVKGQKGSKGDTCGNCTKGE---KGDQGAM 214
            PG+ G PGPKG+ G I          GL G  G  G +GD     T G     G++GA+
Sbjct: 625 GPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAV 684

Query: 215 GSPGLHGGPGAKGEKGEMGEKGEMGD---------KGCCGDSGERGGKGQKGEG--GMKG 263
           G PG+ G PG  G KG  G  G+MG           G  G+ G +G KG+ G G  G+KG
Sbjct: 685 GQPGI-GFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKG 743

Query: 264 EKGSKGDSGMEGKSGRNGLPGAKGD------PGIKGEKGELGPPGLLGPTGPKG--DIGN 315
             G  G  G  G+ G  G+PG  G+      PG++G +GE GPPGL G  G  G   IG 
Sbjct: 744 LPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGP 803

Query: 316 KGVRGPTGKKGSRGFKGSKG 335
            G RGP G +G  G  G  G
Sbjct: 804 PGARGPPGGQGPPGLSGPPG 823



 Score =  166 bits (420), Expect = 4e-41
 Identities = 110/297 (37%), Positives = 131/297 (44%), Gaps = 70/297 (23%)

Query: 103 DCCSPVPGQKGEPGETGQ----------------------------PGPKGEAGNLGIPG 134
           +C    PG +G PG  GQ                            PGP+G  G +G PG
Sbjct: 433 ECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPG 492

Query: 135 PP---------------GVVGPQGPRGYKGEKGLKGE----------RGDQGVPGYPGKP 169
            P               GV GPQG  G  G+ G KGE          +GD+G PG+PG+P
Sbjct: 493 QPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQP 552

Query: 170 GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHG-----GPG 224
           G  G  G  G  G+ GL G KG  GS G       KGE+G  G +G PG  G     GP 
Sbjct: 553 GMTGRAGSPGRDGHPGLPGPKGSPGSVG------LKGERGPPGGVGFPGSRGDTGPPGPP 606

Query: 225 AKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGE----GGMKGEKGSKGDSGMEGKSGRN 280
             G  G +G+KG+ G  G  G  G  G KG+ G+     G  G +G  G  G  G  G  
Sbjct: 607 GYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDR 666

Query: 281 GLPGAKGDPGIKGEKGELGPPGL--LGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
           G PG  G PG+ GEKG +G PG+   GP GPKG  G  G  GP G  G  GF G  G
Sbjct: 667 GFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPG 723



 Score =  166 bits (420), Expect = 4e-41
 Identities = 117/300 (39%), Positives = 137/300 (45%), Gaps = 48/300 (16%)

Query: 103 DCCSPVPGQKGEPGETGQPGPKGEAGNL-------------GIPGPPGVVGP-------- 141
           D  + VPG +G PG  GQPG KGE G               G PG PG+ G         
Sbjct: 506 DGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDG 565

Query: 142 ----QGPRGYKGEKGLKGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKG 197
                GP+G  G  GLKGERG  G  G+PG  G  G PGP G  G  G  G KGQ G  G
Sbjct: 566 HPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPG-YGPAGPIGDKGQAGFPG 624

Query: 198 DTCGNCTKGEKGDQGAM----GSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGK 253
                   G KG+ G +    G PG  G PG+ G  G  G++G  G  G  G  GE+G  
Sbjct: 625 GPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAV 684

Query: 254 GQKGEG-----GMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGP-------- 300
           GQ G G     G KG  G  GD G  G  GR G  G  G+PG++G+KGE G         
Sbjct: 685 GQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGL 744

Query: 301 ---PGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELA--RVPRSAFSAGLSKPFPP 355
              PG+ G  G KG IG  GV G  G  G  G +G +GE     +P S  S G+    PP
Sbjct: 745 PGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPP 804



 Score =  165 bits (417), Expect = 1e-40
 Identities = 111/272 (40%), Positives = 130/272 (47%), Gaps = 31/272 (11%)

Query: 107 PVPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGL--KGERGDQGVPG 164
           P+PG  G  G  G PG  G  G+ G PG PG  G  G +G  G+ G+   G  G +GV G
Sbjct: 643 PLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDG 702

Query: 165 YPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPG 224
            PG  G  G PG  G  G  G  GV+GQKG  G           G  G  G PGL G PG
Sbjct: 703 LPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPG----------VGLPGLKGLPGLPGIPG 752

Query: 225 AKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSK-----GDSGMEGKSGR 279
             GEKG +G  G  G+ G  G  G +G +G+ G  G+ G  GS      G  G  G  G 
Sbjct: 753 TPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGG 812

Query: 280 NGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKK------------GS 327
            G PG  G PGIKGEKG  G PGL  P GPKGD G +G+ G TG+             G 
Sbjct: 813 QGPPGLSGPPGIKGEKGFPGFPGLDMP-GPKGDKGAQGLPGITGQSGLPGLPGQQGAPGI 871

Query: 328 RGFKGSKGELARVPRSAFSAGLSKPFPPPNIP 359
            GF GSKGE+  V  +    G   P   P +P
Sbjct: 872 PGFPGSKGEMG-VMGTPGQPGSPGPVGAPGLP 902



 Score =  137 bits (346), Expect = 2e-32
 Identities = 84/193 (43%), Positives = 99/193 (51%), Gaps = 13/193 (6%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKG------EKGLKGERGDQG 161
            +PG  G PG  G  G KG+ GN G PG PGV GP+G  G++G        G+ G +GD G
Sbjct: 1249 LPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMG 1308

Query: 162  VPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCG----NCTKGEKGDQGAMGSP 217
             PG PG  G +G PG +G KG+ G  GV G KG  G        +  KGE G  G  G P
Sbjct: 1309 PPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPP 1368

Query: 218  GLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKS 277
            GL G  G  G KG+ G  G +G  G  G  G  G  GQKGE    G  G  G  G  G  
Sbjct: 1369 GLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGE---MGPAGPTGPRGFPGPP 1425

Query: 278  GRNGLPGAKGDPG 290
            G +GLPG+ G PG
Sbjct: 1426 GPDGLPGSMGPPG 1438



 Score =  100 bits (250), Expect = 2e-21
 Identities = 68/186 (36%), Positives = 82/186 (44%), Gaps = 39/186 (20%)

Query: 194 GSKGDTCGNC----TKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGE 249
           G  G  CG C     KG+KG++G  G  G+ G PG +G +G  G  G+ GD G       
Sbjct: 30  GCAGSGCGKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTG------- 82

Query: 250 RGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDP---------GIKGEKGELGP 300
                + G  G KG +G  G SG  G  G  G+PG  G P         G KGE+G LGP
Sbjct: 83  -----EPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGP 137

Query: 301 PGLLGPTGPKGDIGNKGVRGPTGK----------KGSRGFKGSKGELARVPRSAFSAGLS 350
           PGL G  G  G  G  G++G  G+          KG RGF G  G     P      GL 
Sbjct: 138 PGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPG----TPGPPGLPGLQ 193

Query: 351 KPFPPP 356
            P  PP
Sbjct: 194 GPVGPP 199



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 35/79 (44%), Positives = 39/79 (49%), Gaps = 13/79 (16%)

Query: 108  VPGQKGEPGETGQ---PGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPG 164
            +PG KG+ G TG    PGP G  G  G PG  G +GP GP          G RG  G PG
Sbjct: 1376 LPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGP---------TGPRGFPGPPG 1426

Query: 165  YPGKPGAQGEPG-PKGDKG 182
              G PG+ G PG P  D G
Sbjct: 1427 PDGLPGSMGPPGTPSVDHG 1445


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  196 bits (497), Expect = 5e-50
 Identities = 107/245 (43%), Positives = 122/245 (49%), Gaps = 18/245 (7%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
            G KG+ GE G PGP G  G +G PGP G  G  GPRG +G  G KG+ G +G PG PG  
Sbjct: 1168 GSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPV 1227

Query: 170  GAQGEPGPKGDKGNI------------------GLGGVKGQKGSKGDTCGNCTKGEKGDQ 211
            G QG PGP G+KG                    G  G  G +G  G        GEKG+ 
Sbjct: 1228 GLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEP 1287

Query: 212  GAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDS 271
            G  G PGL G  G  G KGE GEKGE G  G  G  G +G  G  G  G  G  G  GD 
Sbjct: 1288 GEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDP 1347

Query: 272  GMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFK 331
            G  G+ G  G  G  GD G  GE G+ G PG  G  GP G  G +G  GP G +G +G K
Sbjct: 1348 GPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEK 1407

Query: 332  GSKGE 336
            G+KGE
Sbjct: 1408 GAKGE 1412



 Score =  194 bits (493), Expect = 1e-49
 Identities = 106/236 (44%), Positives = 130/236 (55%), Gaps = 12/236 (5%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGP---PGVVGPQGPRGYKGEKGLKGE------RGD 159
            PG  G PGE G PG  G+ G  G PGP   PG  GP G RG+ G++GL G       +G+
Sbjct: 1017 PGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGN 1076

Query: 160  QGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGL 219
            +G PG PG  G+ GE GP G  G IG+ G  G +G  G        GEKG QG  G  GL
Sbjct: 1077 EGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGL 1136

Query: 220  HGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGR 279
             G  G  G  G +G  GE GDKG  G+ G++G KG KGE G  G  G +G  G  G SG 
Sbjct: 1137 QGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGA 1196

Query: 280  NGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
            +G PG +G  G+ G+KG+ GP G  GP GP   +G +G+ GP G+KG  G  G  G
Sbjct: 1197 DGEPGPRGQQGLFGQKGDEGPRGFPGPPGP---VGLQGLPGPPGEKGETGDVGQMG 1249



 Score =  192 bits (487), Expect = 7e-49
 Identities = 113/268 (42%), Positives = 135/268 (50%), Gaps = 34/268 (12%)

Query: 110  GQKGEPGETGQ---------PGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQ 160
            G+KGEPGE G+         PGPKGE G  G  GP G  GP GP+G  G+ G KG  G  
Sbjct: 1282 GEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPV 1341

Query: 161  GV---PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSP 217
            G    PG PG+PG  G+ GP GDKG+ G  G  G  G  G+       G  G  G  G P
Sbjct: 1342 GFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGE------PGPSGPPGKRGPP 1395

Query: 218  GLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKS 277
            G  G  G +GEKG  GE G  G  G  G  G +G  G+ G  G++G  G  G+ G+ G  
Sbjct: 1396 GPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSP 1455

Query: 278  GRNGLPGAKGDPGIKGEKGELGP------PGLLGPTGPKGDIGNKGVRGPTGKKGSRGFK 331
            G +G PG  G PG+ G KG+ GP      PGL+G  GP G+ G KG RG  G +GS G K
Sbjct: 1456 GPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPK 1515

Query: 332  GSKGELARVPRSAFSAGLSKPFPPPNIP 359
            G +G            G S P  PP  P
Sbjct: 1516 GEQG----------ITGPSGPIGPPGPP 1533



 Score =  191 bits (486), Expect = 1e-48
 Identities = 109/254 (42%), Positives = 127/254 (50%), Gaps = 22/254 (8%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG+KGE G+ GQ GP G  G  G  G PG  GPQGP G  G  G  GE+G+ G  G PG 
Sbjct: 1236 PGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGL 1295

Query: 169  PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSP---GLHGGPGA 225
            PG  G PGPKG++G  G  G  G  G  G       KG  GD G  GSP   G  G PG 
Sbjct: 1296 PGEGGPPGPKGERGEKGESGPSGAAGPPG------PKGPPGDDGPKGSPGPVGFPGDPGP 1349

Query: 226  KGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGA 285
             GE G  G+ G  GDKG  G+ G+ G  G  GE G  G  G +G  G  G  GR G  GA
Sbjct: 1350 PGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGA 1409

Query: 286  KGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAF 345
            KG+ G++G  G+ GP   +GP G  G  G  G+RG  G  G +G  GS G          
Sbjct: 1410 KGEAGLEGPPGKTGP---IGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPG---------- 1456

Query: 346  SAGLSKPFPPPNIP 359
              G   P  PP +P
Sbjct: 1457 PDGPPGPMGPPGLP 1470



 Score =  191 bits (484), Expect = 2e-48
 Identities = 104/238 (43%), Positives = 135/238 (56%), Gaps = 6/238 (2%)

Query: 103 DCCSPVPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGV 162
           D  + +PG+KG  G+ G  GP G  G+ G  G  G VGP+G  G  G +GL G +G  G 
Sbjct: 633 DGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGP 692

Query: 163 PGYPGKPGAQGEPGPKGD---KGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGL 219
           PG PG  G  G+PGPKG+   +G  G  G +G  G++G        G  G++G +G PGL
Sbjct: 693 PGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGL 752

Query: 220 HGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGR 279
            G PGA G  G  G++G  G+KG  G  G +G  G  G  G+KG  G +G  G +G+ G 
Sbjct: 753 PGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGE 812

Query: 280 NGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGEL 337
           +G PG KGD GIKG++GE+GPPG  G  GP+G    KG  GP G  G  G  G KG+L
Sbjct: 813 DGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGP---KGRGGPNGDPGPLGPPGEKGKL 867



 Score =  190 bits (483), Expect = 2e-48
 Identities = 114/270 (42%), Positives = 139/270 (51%), Gaps = 20/270 (7%)

Query: 109 PGQKGEPGETGQPGPKGEAGN---LGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGY 165
           PG KG  G  G+PGP G+ GN    G+PGP G +GP G +G  G+ GL G  G  G PG+
Sbjct: 705 PGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGH 764

Query: 166 PGK---PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
           PGK   PG +G  GP G +G IG  G +G KG+ G      TKGEKG+    G PG  G 
Sbjct: 765 PGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGED---GFPGFKGD 821

Query: 223 PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRN-- 280
            G KG++GE+G  G  G+ G  G  G  G  G  G  G  GEKG  G  G+ G  GR   
Sbjct: 822 MGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGP 881

Query: 281 -------GLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGS 333
                  G PGA G+ G +G  G+ GP G  GPTGP+G+ G +G+ G  G KG+ G  G 
Sbjct: 882 KGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGP 941

Query: 334 KGELA-RVPRSAFS-AGLSKPFPPPNIPIK 361
            G    R P       G   P  PP  P K
Sbjct: 942 AGPPGERGPNGPQGPTGFPGPKGPPGPPGK 971



 Score =  190 bits (483), Expect = 2e-48
 Identities = 111/260 (42%), Positives = 137/260 (52%), Gaps = 19/260 (7%)

Query: 109  PGQKGEPG---ETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGY 165
            PG+ GEPG   E G PGPKGE G  G  GP G  GP GP+G  G+ G KG  G  G PG 
Sbjct: 1287 PGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGD 1346

Query: 166  PG---KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
            PG   +PG  G+ GP GDKG+ G  G  G  G  G+   +   G++G  G  G  G  G 
Sbjct: 1347 PGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGE 1406

Query: 223  PGAKGE---KGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGR 279
             GAKGE   +G  G+ G +G +G  G  G  G +G  G  G +G  GS G  G  G  G 
Sbjct: 1407 KGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGP 1466

Query: 280  NGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELAR 339
             GLPG KGD G KGEKG  G  GL+GP G +G+ G++G+ GP G  G +G +G  G    
Sbjct: 1467 PGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITG---- 1522

Query: 340  VPRSAFSAGLSKPFPPPNIP 359
                   +G   P  PP +P
Sbjct: 1523 ------PSGPIGPPGPPGLP 1536



 Score =  189 bits (481), Expect = 4e-48
 Identities = 108/240 (45%), Positives = 126/240 (52%), Gaps = 12/240 (5%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG  GE G  G+ GP+G AG  G+ GP G+ GP GP G  GE G KGE G+ G  G  G 
Sbjct: 1113 PGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGD 1172

Query: 169  PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSP---------GL 219
             G QG PGP G +G IG  G  G  G  G        G+KGD+G  G P         GL
Sbjct: 1173 KGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGL 1232

Query: 220  HGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGR 279
             G PG KGE G++G+ G  G  G  G SG  G  G +G  G  G  G+ G+ G  G++G 
Sbjct: 1233 PGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGE 1292

Query: 280  NGLPGAKGDPGIK---GEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
             GLPG  G PG K   GEKGE GP G  GP GPKG  G+ G +G  G  G  G  G  GE
Sbjct: 1293 PGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGE 1352



 Score =  189 bits (480), Expect = 5e-48
 Identities = 99/237 (41%), Positives = 132/237 (55%), Gaps = 9/237 (3%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
           +PG  G PG  G+ GP GE G  G PGP G +G  GPRG KG  G++G +G +G  G  G
Sbjct: 755 MPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDG 814

Query: 168 KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGE------KGDQGAMGSPGLHG 221
            PG +G+ G KGD+G IG  G +G+ G +G        G+       G++G +G PGL G
Sbjct: 815 FPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPG 874

Query: 222 GPGAKGEKGEM---GEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSG 278
            PG +G KG +   G  G  G+KG  G  G+ G +GQ+G  G +GE+G +G +G  G  G
Sbjct: 875 YPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKG 934

Query: 279 RNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
            +G  G  G PG +G  G  GP G  GP GP G  G  G+ G  G++G  GF+G  G
Sbjct: 935 NSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 991



 Score =  187 bits (474), Expect = 2e-47
 Identities = 109/252 (43%), Positives = 127/252 (50%), Gaps = 24/252 (9%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGD------QGV 162
            PG  G  G  G+ GP G AG +GIPG PG  GP GP G KG  G KG +G       QG 
Sbjct: 1080 PGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGP 1139

Query: 163  PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
             G PG  G  G PG  GDKG IG  G KG KG KG+       G +G  G  G  G  G 
Sbjct: 1140 VGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGE 1199

Query: 223  PGAKGEKGEMGEKGEMGDKG------------CCGDSGERGGKGQKGEGGMKGEKGSKGD 270
            PG +G++G  G+KG+ G +G              G  GE+G  G  G+ G  G  G +G 
Sbjct: 1200 PGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGP 1259

Query: 271  SGMEGKSGRNGLPGAKGDPGIKGEKGELGP------PGLLGPTGPKGDIGNKGVRGPTGK 324
            SG  G  G  G PG  G+PG  GEKGE G       PG  GP GPKG+ G KG  GP+G 
Sbjct: 1260 SGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGA 1319

Query: 325  KGSRGFKGSKGE 336
             G  G KG  G+
Sbjct: 1320 AGPPGPKGPPGD 1331



 Score =  186 bits (472), Expect = 4e-47
 Identities = 105/251 (41%), Positives = 130/251 (51%), Gaps = 24/251 (9%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           G  G  G TG+PGP G  G+ G+ G PG VGPQGPRG +G  G  G+ G +G  G  G  
Sbjct: 559 GPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGAR 618

Query: 170 GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGS------------- 216
           G  G+ GPKGD+G  GL G+ G+KG +GD   +   G  GD G  G              
Sbjct: 619 GMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEP 678

Query: 217 -----------PGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEK 265
                      PG  G PG  G  G+ G KG +G +G  G  G++G  G +G  G +G  
Sbjct: 679 GPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAI 738

Query: 266 GSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKK 325
           G  G+ G  GK G  G+PGA G PG  G++G  G  G  GP GP+G IG  G RG  G  
Sbjct: 739 GPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGAD 798

Query: 326 GSRGFKGSKGE 336
           G RG KG+KGE
Sbjct: 799 GIRGLKGTKGE 809



 Score =  186 bits (472), Expect = 4e-47
 Identities = 101/227 (44%), Positives = 127/227 (55%), Gaps = 9/227 (3%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           G +G PG  G+PG +G AG+ G  G PG  GP+G RG+ G  GL GE+G +G PG  G P
Sbjct: 595 GVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPP 654

Query: 170 GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
           G  G+ G +GD G +G  G+ G+ G +G        G KG  G  G PG+ G  G  G K
Sbjct: 655 GPPGDDGERGDDGEVGPRGLPGEPGPRG------LLGPKGPPGPPGPPGVTGMDGQPGPK 708

Query: 230 GEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDP 289
           G +G +GE G  G  G+ G +G  G +G  G  GEKG  G  G+ G  G +G PG  G  
Sbjct: 709 GNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKE 768

Query: 290 GIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
           G  GEKG  GPP   GP GP G  G +GV+G  G +G +G KG KGE
Sbjct: 769 GPPGEKGGQGPP---GPQGPIGYPGPRGVKGADGIRGLKGTKGEKGE 812



 Score =  186 bits (471), Expect = 5e-47
 Identities = 103/217 (47%), Positives = 119/217 (54%), Gaps = 12/217 (5%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
            G  GEPG+TG PGP GE G  G PG  G  GP GP G +GEKG KGE G +G PG  G  
Sbjct: 1366 GDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPI 1425

Query: 170  GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
            G QG PG  G  G  G+ G  G++G  G      + G  G  G MG PGL   PG KG+ 
Sbjct: 1426 GPQGAPGKPGPDGLRGIPGPVGEQGLPG------SPGPDGPPGPMGPPGL---PGLKGDS 1476

Query: 230  GEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDP 289
            G  GEKG  G  G  G  GE+G KG +G  G +G  G KG+ G+ G SG  G P   G P
Sbjct: 1477 GPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPP---GPP 1533

Query: 290  GIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKG 326
            G+ G  G  G  G  GPTGPKG+ G+ G  GP G  G
Sbjct: 1534 GLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPG 1570



 Score =  185 bits (470), Expect = 7e-47
 Identities = 105/246 (42%), Positives = 129/246 (52%), Gaps = 18/246 (7%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQ------GPRGYKGEKGLKGERGDQGV 162
            PG+ G PG  GQ G  G  G  G PGPPGVVGPQ      GP G +G  G  G  G+QG+
Sbjct: 969  PGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGL 1028

Query: 163  PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
            PG  GK G +G+PGP G  G  G  G++G  G +G        G KG++G  G PG  G 
Sbjct: 1029 PGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGS 1088

Query: 223  PGAK---GEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGR 279
            PG +   G  G +G  G  G +G  G +GE+G  G+KG  G  G  G +G  G+ G +G 
Sbjct: 1089 PGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGP 1148

Query: 280  NGLPGAKGD---------PGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGF 330
             G PG  GD          G KG+KGE GPPG  GP GP G  G  G  G  G +G +G 
Sbjct: 1149 VGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGL 1208

Query: 331  KGSKGE 336
             G KG+
Sbjct: 1209 FGQKGD 1214



 Score =  182 bits (463), Expect = 4e-46
 Identities = 113/266 (42%), Positives = 136/266 (51%), Gaps = 28/266 (10%)

Query: 109 PGQKGEPGETG---QPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGL---KGERGDQGV 162
           PG  G PG TG   QPGPKG  G  G PGPPG  G  G +G  G +G     GE+G  G 
Sbjct: 690 PGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGK 749

Query: 163 PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
           PG PG PGA G PG  G +G  G  G +G  G +G        G  G +G  G+ G+ G 
Sbjct: 750 PGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPI------GYPGPRGVKGADGIRGL 803

Query: 223 PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDS------GMEGK 276
            G KGEKGE G  G  GD G  GD GE G  G +GE G +G KG  G +      G  G+
Sbjct: 804 KGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGE 863

Query: 277 SGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGN------KGVRGPTGKKGSRGF 330
            G+ G+PG  G PG +G KG +G PG  G  G KG  G       +G RGPTG +G RG 
Sbjct: 864 KGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGP 923

Query: 331 KGSKGELARVPRSAFSAGLSKPFPPP 356
           +G  G+    P    ++G   P  PP
Sbjct: 924 RGITGK----PGPKGNSGGDGPAGPP 945



 Score =  181 bits (458), Expect = 2e-45
 Identities = 105/245 (42%), Positives = 125/245 (51%), Gaps = 21/245 (8%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG KG PG+ G  G  G  G  G PGPPG  GP G  G  G+KG  GE G  G PG  G+
Sbjct: 1323 PGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGE 1382

Query: 169  PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGE 228
            PG  G PG +G  G  G  G +G+KG+KG+       G+ G  G  G+PG  G  G +G 
Sbjct: 1383 PGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGI 1442

Query: 229  KGEMGEKG------------EMGDKGCCGDSGERGGKGQKGEGGM------KGEKGSKGD 270
             G +GE+G             MG  G  G  G+ G KG+KG  G+       GE+G KGD
Sbjct: 1443 PGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGD 1502

Query: 271  SGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGF 330
             G+ G  G +G  G +G  G  G  G  GPPGL GP GPK   G KG  GPTG KG  G 
Sbjct: 1503 RGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPK---GAKGSSGPTGPKGEAGH 1559

Query: 331  KGSKG 335
             G  G
Sbjct: 1560 PGPPG 1564



 Score =  180 bits (457), Expect = 2e-45
 Identities = 120/279 (43%), Positives = 133/279 (47%), Gaps = 33/279 (11%)

Query: 110  GQKGEPGETGQPGPKGE---AGNLGIPGPPGVVGPQGPRGYKGE---------KGLKGER 157
            G+KG PGE G  GP G     G +G+PGP G VGP G  G KGE         KG KGE+
Sbjct: 1117 GEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQ 1176

Query: 158  ------GDQGVPGYPGKPGAQGEPGP---------KGDKGNIGLGGVKGQKGSKGDTCGN 202
                  G QG  G PG  GA GEPGP         KGD+G  G  G  G  G +G     
Sbjct: 1177 GPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPP 1236

Query: 203  CTKGEKGDQGAMGSPGLHG--GP-GAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQ---K 256
              KGE GD G MG PG  G  GP GA G  G  G  G +G+ G  G+ GE G  G+    
Sbjct: 1237 GEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLP 1296

Query: 257  GEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNK 316
            GEGG  G KG +G+ G  G SG  G PG KG PG  G KG  GP G  G  GP G+ G  
Sbjct: 1297 GEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPA 1356

Query: 317  GVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPP 355
            G  GP G KG  G  G  G          S    K  PP
Sbjct: 1357 GQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPP 1395



 Score =  179 bits (455), Expect = 4e-45
 Identities = 106/238 (44%), Positives = 123/238 (51%), Gaps = 12/238 (5%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVG------PQGPRGYKGEKGLKGERGDQGVP 163
           G +G PGE G  G  G  G  G PGPPGV G      P+G  G +GE G  G++G+ G  
Sbjct: 670 GPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQ 729

Query: 164 GYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEK------GDQGAMGSP 217
           G PG  GA G PG KG  G  GL G+ G  G  G        GEK      G QG +G P
Sbjct: 730 GLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYP 789

Query: 218 GLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKS 277
           G  G  GA G +G  G KGE G+ G  G  G+ G KG +GE G  G +G  G  G +G+ 
Sbjct: 790 GPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRG 849

Query: 278 GRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
           G NG PG  G PG KG+ G  G PG  G  GPKG IG  G  G  G+KG RG  G  G
Sbjct: 850 GPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPG 907



 Score =  179 bits (453), Expect = 6e-45
 Identities = 108/280 (38%), Positives = 135/280 (48%), Gaps = 37/280 (13%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKG------LKGERGDQGVP 163
            G+ G PG  G  G KG+ G +G PGP G  GP+GP+G  G  G        GE+G  GVP
Sbjct: 811  GEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVP 870

Query: 164  GYPGKPGAQGE---------PGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAM 214
            G PG PG QG          PG  G+KG  G  G  G +G +G T     +GE+G +G  
Sbjct: 871  GLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTG---PRGERGPRGIT 927

Query: 215  GSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGME 274
            G PG  G  G  G  G  GE+G  G +G  G  G +G  G  G+ G+ G  G +G++G +
Sbjct: 928  GKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 987

Query: 275  GKSGRNGLPGA---------------KGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVR 319
            GK+G  G PG                +G PG  G  GE G PGL G  G KGD G  G+ 
Sbjct: 988  GKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLP 1047

Query: 320  GPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPPPNIP 359
            G  G  G RGF G +G    +P    + GL     PP  P
Sbjct: 1048 GKDGPPGLRGFPGDRG----LPGPVGALGLKGNEGPPGPP 1083



 Score =  178 bits (452), Expect = 8e-45
 Identities = 105/264 (39%), Positives = 132/264 (50%), Gaps = 14/264 (5%)

Query: 110  GQKGEPGETGQPGP---KGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYP 166
            G KG  G  G PGP    GE G LG+PG PG  G QGP+G  G  G  G  G++G  G P
Sbjct: 844  GPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTP 903

Query: 167  GKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAK 226
            GKPG +G+ GP G +G  G  G+ G+ G KG++ G+   G  G++G  G  G  G PG K
Sbjct: 904  GKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPK 963

Query: 227  GE---------KGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKS 277
            G           G  G++GE G +G  G  G  G  G +G  G  G  G +G  G  G  
Sbjct: 964  GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPP 1023

Query: 278  GRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE- 336
            G  GLPG  G  G KG+ G  G PG  GP G +G  G++G+ GP G  G +G +G  G  
Sbjct: 1024 GEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPP 1083

Query: 337  -LARVPRSAFSAGLSKPFPPPNIP 359
              A  P     AG + P   P  P
Sbjct: 1084 GPAGSPGERGPAGAAGPIGIPGRP 1107



 Score =  178 bits (452), Expect = 8e-45
 Identities = 100/229 (43%), Positives = 119/229 (51%), Gaps = 6/229 (2%)

Query: 110  GQKGEPGETGQPGPKGEAG---NLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYP 166
            GQ G  G  G+PGP+G+ G     G  GP G  GP GP G +G  G  GE+G+ G  G  
Sbjct: 1189 GQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQM 1248

Query: 167  GKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAK 226
            G P   G PGP+G  G  G  G +G  G  G+      KGE G+ G  G PG  G PG K
Sbjct: 1249 GPP---GPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPK 1305

Query: 227  GEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAK 286
            GE+GE GE G  G  G  G  G  G  G KG  G  G  G  G  G  G +G++G PG K
Sbjct: 1306 GERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDK 1365

Query: 287  GDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
            GD G  G+ G  GP G  GP+GP G  G  G  GP G++G +G KG  G
Sbjct: 1366 GDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAG 1414



 Score =  171 bits (433), Expect = 1e-42
 Identities = 97/247 (39%), Positives = 122/247 (49%), Gaps = 18/247 (7%)

Query: 109  PGQKGEPGETGQ---------PGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGD 159
            PG  G PGE G+         PG +G  G++G PG PG  G +G RG  G+ G +G+RG 
Sbjct: 855  PGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGP 914

Query: 160  QGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGL 219
             G  G  G  G  G+PGPKG+ G  G  G  G++G  G        G KG  G  G  GL
Sbjct: 915  TGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGL 974

Query: 220  HGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGR 279
             G PG +GE G  G+ G  G  G  G  G  G  G  GE G  G  G  G+ G+ G +G+
Sbjct: 975  PGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGK 1034

Query: 280  N---------GLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGF 330
                      GLPG  G PG++G  G+ G PG +G  G KG+ G  G  GP G  G RG 
Sbjct: 1035 EGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGP 1094

Query: 331  KGSKGEL 337
             G+ G +
Sbjct: 1095 AGAAGPI 1101



 Score =  169 bits (428), Expect = 5e-42
 Identities = 100/259 (38%), Positives = 121/259 (46%), Gaps = 33/259 (12%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG-- 167
            G  G+PG  G PG KG+ G  G+PG PG  GP+G  G+ G  G  GE+G +G PG PG  
Sbjct: 850  GPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPR 909

Query: 168  -------------------KPGAQ------------GEPGPKGDKGNIGLGGVKGQKGSK 196
                               KPG +            GE GP G +G  G  G KG  G  
Sbjct: 910  GQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPP 969

Query: 197  GDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQK 256
            G        G++G+ G  G  G  G PG  G +G  GE G MG++G  G  G  G +G  
Sbjct: 970  GKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLP 1029

Query: 257  GEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNK 316
            G  G +G KG  G +G+ GK G  GL G  GD G+ G  G LG  G  GP GP G  G+ 
Sbjct: 1030 GLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSP 1089

Query: 317  GVRGPTGKKGSRGFKGSKG 335
            G RGP G  G  G  G  G
Sbjct: 1090 GERGPAGAAGPIGIPGRPG 1108



 Score =  168 bits (426), Expect = 9e-42
 Identities = 110/297 (37%), Positives = 134/297 (45%), Gaps = 69/297 (23%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVV------------------------------ 139
           GQ G+PGE G PG  G  G  G+PGPPG +                              
Sbjct: 490 GQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAI 549

Query: 140 ---------GPQGPRGYKGEKG---------LKGERGD---QGVPGYPGKPGAQGEPGPK 178
                    GP GP G  G  G         LKGE GD   QG  G  G PG  G+PG +
Sbjct: 550 LQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRR 609

Query: 179 GDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEM 238
           G  G+ G  G+ GQ G KGD   +   G  G++G  G PG  G PG  G+ GE G+ GE+
Sbjct: 610 GRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEV 669

Query: 239 GDKGCCGDSGERGGKGQKGE---------GGMKGEKGSKGD---------SGMEGKSGRN 280
           G +G  G+ G RG  G KG           GM G+ G KG+          G +G  G  
Sbjct: 670 GPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQ 729

Query: 281 GLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGEL 337
           GLPG +G  G  GEKG LG PGL G  G  G  G+ G  GP G+KG +G  G +G +
Sbjct: 730 GLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPI 786



 Score =  164 bits (414), Expect = 2e-40
 Identities = 97/236 (41%), Positives = 114/236 (48%), Gaps = 9/236 (3%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGI---PGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGY 165
            PG+ G  G+ G  GP+GE G  GI   PGP G  G  GP G  GE+G  G +G  G PG 
Sbjct: 903  PGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGP 962

Query: 166  ---PGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
               PG PG  G PG  G +G  G  G  G  G  G        GE G  G  G PG  G 
Sbjct: 963  KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGP 1022

Query: 223  PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGL 282
            PG +G  G  G++G  GD G  G  G+ G  G +G  G +G  G  G  G++G  G  G 
Sbjct: 1023 PGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGP 1082

Query: 283  PGAKGDPGIKGEKGELGP---PGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
            PG  G PG +G  G  GP   PG  GP GP G  G KG  G  G +G  G  G +G
Sbjct: 1083 PGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQG 1138



 Score =  163 bits (413), Expect = 3e-40
 Identities = 99/273 (36%), Positives = 123/273 (45%), Gaps = 46/273 (16%)

Query: 108 VPGQKGEPGETGQP----------GPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGER 157
           + G +GE G+ G+P          GP G  G  G+PGPPG +GP G  G  GE+G  G  
Sbjct: 445 IGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRP 504

Query: 158 GDQGVPGYPGKPGAQ----------GEPGPKGD--------------------KGNIGLG 187
           G  G  G PG PG            G+ G KG                     +G  G  
Sbjct: 505 GLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPM 564

Query: 188 GVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDS 247
           G+ G+ G  G       KGE GD G  G  G+ G PG  G+ G  G  G  G +G  G +
Sbjct: 565 GLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQT 624

Query: 248 GERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPT 307
           G +G +G  G  G+ GEKG +GD G  G       PG  GD G +G+ GE+GP GL G  
Sbjct: 625 GPKGDRGFDGLAGLPGEKGHRGDPGPSGP------PGPPGDDGERGDDGEVGPRGLPGEP 678

Query: 308 GPKGDIGNKGVRGPTGKKGSRGFKGSKGELARV 340
           GP+G +G KG  GP G  G  G  G  G    V
Sbjct: 679 GPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNV 711



 Score =  146 bits (369), Expect = 4e-35
 Identities = 84/195 (43%), Positives = 96/195 (49%), Gaps = 15/195 (7%)

Query: 109  PGQKGEPGETGQPGP---------KGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGD 159
            PG  G PG+ G PGP         KG  G  G+ GPPG  GP GP+G  G+ G  G RG 
Sbjct: 1383 PGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGI 1442

Query: 160  QGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGL 219
             G  G  G PG+ G  GP G  G  GL G+KG  G KG+      KG  G  G +G PG 
Sbjct: 1443 PGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGE------KGHPGLIGLIGPPGE 1496

Query: 220  HGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGR 279
             G  G +G  G  G  G  G++G  G SG  G  G  G  G  G KG+KG SG  G  G 
Sbjct: 1497 QGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGE 1556

Query: 280  NGLPGAKGDPGIKGE 294
             G PG  G PG  GE
Sbjct: 1557 AGHPGPPGPPGPPGE 1571



 Score =  110 bits (274), Expect = 4e-24
 Identities = 90/294 (30%), Positives = 119/294 (40%), Gaps = 43/294 (14%)

Query: 109 PGQKGEPGETGQ-PGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGY-P 166
           P Q  +PG   + P    +  N   P PP   G     G   E+ ++    +   P Y P
Sbjct: 364 PDQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDP 423

Query: 167 GKPGAQGEPGPKGDKGNI--GLGGVKGQKGSKGDTC----GNCTKGEKGDQGAMGSPGLH 220
               ++  PG   ++  I  G+GG +G+KG KG+      G   +G  G +G  G PG  
Sbjct: 424 TSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPP 483

Query: 221 GGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKG-------QKGEGGMKGEKGS------ 267
           G  G  G+ G+ GE+G  G  G  G  G  G  G       + G GG  G KG       
Sbjct: 484 GTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQE 543

Query: 268 --------------KGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDI 313
                         +G +G  G +GR G  G  G  G+KGE G++GP G  G  GP G  
Sbjct: 544 SQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPA 603

Query: 314 GNKGVRGPTGKKGSRGFKGSKGE--------LARVPRSAFSAGLSKPFPPPNIP 359
           G  G RG  G  G+RG  G  G         LA +P      G   P  PP  P
Sbjct: 604 GKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPP 657



 Score =  101 bits (251), Expect = 2e-21
 Identities = 55/130 (42%), Positives = 66/130 (50%), Gaps = 9/130 (6%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGL---------KGERG 158
            +PG  GE G  G PGP G  G +G PG PG+ G  GP+G KG  GL         +GE+G
Sbjct: 1442 IPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKG 1501

Query: 159  DQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPG 218
            D+G+PG  G  G +GE G  G  G IG  G  G  G  G      + G  G +G  G PG
Sbjct: 1502 DRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPG 1561

Query: 219  LHGGPGAKGE 228
              G PG  GE
Sbjct: 1562 PPGPPGPPGE 1571



 Score = 76.3 bits (186), Expect = 6e-14
 Identities = 36/79 (45%), Positives = 45/79 (56%), Gaps = 3/79 (3%)

Query: 109  PGQKGEPGETGQPGPKGEAG---NLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGY 165
            PG++GE G+ G PGP+G +G     GI GP G +GP GP G  G  G KG +G  G  G 
Sbjct: 1494 PGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGP 1553

Query: 166  PGKPGAQGEPGPKGDKGNI 184
             G+ G  G PGP G  G +
Sbjct: 1554 KGEAGHPGPPGPPGPPGEV 1572



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 28/84 (33%), Positives = 36/84 (42%), Gaps = 7/84 (8%)

Query: 286 KGDPGIKGEKGELGPPGLLGP----TGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVP 341
           +G  G +GEKG+ G P ++ P     GP G  G  G+ GP G  G  G  G  GE     
Sbjct: 443 EGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPG 502

Query: 342 RSAFSAGLSKPFPPPN---IPIKF 362
           R         P PP     +P +F
Sbjct: 503 RPGLPGADGLPGPPGTMLMLPFRF 526


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score =  195 bits (495), Expect = 9e-50
 Identities = 117/266 (43%), Positives = 141/266 (53%), Gaps = 25/266 (9%)

Query: 109  PGQKGEPGETGQPG---------PKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGD 159
            PG+KGEPGE+G PG         P+GE G  G  G PG  GP GP+G  G+ G KG  G 
Sbjct: 1123 PGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGP 1182

Query: 160  QGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGL 219
             G PG PG PG  G  G  G KG+ G  G  GQ GS G T  N   G  G +G  GSPG 
Sbjct: 1183 VGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGS 1242

Query: 220  HG---GPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKG---EGGMKGEKGSKGDSGM 273
             G   G GAKG+ G +G  G+ G  G  G +G+ G  G +G     G +G  G+ G +G 
Sbjct: 1243 EGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGP 1302

Query: 274  EGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGS 333
             G  G  GLPG +GD G KGEKG    PGL+G  GP G+ G KG RG  G +GS G KG 
Sbjct: 1303 PGPVGPPGLPGLRGDAGAKGEKGH---PGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGE 1359

Query: 334  KGELARVPRSAFSAGLSKPFPPPNIP 359
             G    +P ++   G   P  PP +P
Sbjct: 1360 MG----IPGASGPIG---PGGPPGLP 1378



 Score =  193 bits (490), Expect = 3e-49
 Identities = 104/248 (41%), Positives = 128/248 (51%), Gaps = 6/248 (2%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
           +PG  G PG  G+ GP G  GN G  GP G +G  GPRG KG  G++G +G +G  G  G
Sbjct: 597 MPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDG 656

Query: 168 KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKG 227
            PG +G+ G KGD+G +G+ G +G+ G +G        G+ G  G MG  G  G PG  G
Sbjct: 657 FPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPG 716

Query: 228 EKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKG 287
             G  G KG +G  G  G SGE+G +G  G+ G +GE+G  G  G  G  G  G  GAKG
Sbjct: 717 YPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKG 776

Query: 288 DPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSA 347
             G  G  G  G  GL GP GP G  G KG  GP GK G  G  G +GE+       F  
Sbjct: 777 TSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEV------GFQG 830

Query: 348 GLSKPFPP 355
               P PP
Sbjct: 831 KTGPPGPP 838



 Score =  192 bits (488), Expect = 6e-49
 Identities = 112/276 (40%), Positives = 134/276 (48%), Gaps = 34/276 (12%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGP------------QGPRGYKGEKGLKGER 157
            G KGE G+ GQ G KG  G  G PGPPG +GP             G RG +G  G KG+ 
Sbjct: 998  GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1057

Query: 158  GDQGVPGYPGKPGAQGEPGPKGDKGN------------------IGLGGVKGQKGSKGDT 199
            G +G  G PG  G QG PGP G+KG                    G  G  G +G  G  
Sbjct: 1058 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGV 1117

Query: 200  CGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEG 259
                  GEKG+ G  GSPG+ G PG KG +GE GEKGE G  G  G  G +G  G  G  
Sbjct: 1118 GNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPK 1177

Query: 260  GMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVR 319
            G  G  G  GD G  G+ G  G  GAKGD G  GE G+ G PG  G  GP G +G +G  
Sbjct: 1178 GNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPA 1237

Query: 320  GPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPP 355
            G  G +G +G KG+KG+    P +  + G + P  P
Sbjct: 1238 GSPGSEGRQGGKGAKGD----PGAIGAPGKTGPVGP 1269



 Score =  191 bits (486), Expect = 1e-48
 Identities = 108/266 (40%), Positives = 135/266 (50%), Gaps = 17/266 (6%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK- 168
           G  G  GE G PG +G  G  G+PGP G +GP G +G +G+ GL G  G  G PG+PGK 
Sbjct: 551 GSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKE 610

Query: 169 --PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAK 226
             PG +G  GP G +G +G  G +G KG  G       KG KG++G  G PG  G  G K
Sbjct: 611 GPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGI---RGLKGHKGEKGEDGFPGFKGDIGVK 667

Query: 227 GEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNG----- 281
           G++GE+G  G  G+ G  G  G  G  G  G  G+ GEKG  G  G+ G  GR G     
Sbjct: 668 GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL 727

Query: 282 ----LPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGEL 337
                PGA G+ G +G  G+ GP G  GPTGP+G  G +G  G +G KG+ G  G  G  
Sbjct: 728 GFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPP 787

Query: 338 AR--VPRSAFSAGLSKPFPPPNIPIK 361
               +P      G   P  PP  P K
Sbjct: 788 GERGLPGPQGPNGFPGPKGPPGPPGK 813



 Score =  189 bits (480), Expect = 5e-48
 Identities = 110/250 (44%), Positives = 140/250 (56%), Gaps = 27/250 (10%)

Query: 109 PGQKGE------PGETGQPGPKGEAGNLGIPGPPGVVGPQG------PRGYKGEKGLKGE 156
           PG KG+      PG  G+ G +G+ G  G+PGPPG  G +G      PRG  GE G +G 
Sbjct: 466 PGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGL 525

Query: 157 RGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAM-- 214
            G +G PG PG PG +G  GP+G KG++G  G  G  G +G T G  T+G  G QGA+  
Sbjct: 526 LGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQG-TPG--TQGLPGPQGAIGP 582

Query: 215 -------GSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGS 267
                  G PGL G PG+ G  G  G++G  G KG  G SG +G  G  G  G+KG  G 
Sbjct: 583 HGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGI 642

Query: 268 KGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGS 327
           +G  G +G+ G +G PG KGD G+KG++GE+G PG  G  GP+G    KG  GPTG  G 
Sbjct: 643 RGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGP---KGRTGPTGDPGP 699

Query: 328 RGFKGSKGEL 337
            G  G KG+L
Sbjct: 700 PGLMGEKGKL 709



 Score =  187 bits (475), Expect = 2e-47
 Identities = 106/252 (42%), Positives = 126/252 (50%), Gaps = 13/252 (5%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
            +PG  GE GETG  GP G  G  G  GP G  G  GP+G  G  G  G  G++G PG  G
Sbjct: 1074 LPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESG 1133

Query: 168  KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKG 227
             PG QGEPG KG +G  G  G  GQ G  G        G+ G +G  G  G  G PG  G
Sbjct: 1134 SPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG 1193

Query: 228  EKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKG 287
            E G  G+ G  GD+G  G+ G+ G  G  GE G  G  G +G +G  G  GR G  GAKG
Sbjct: 1194 EGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKG 1253

Query: 288  DPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSA 347
            DPG  G  G+ GP   +GP GP G  G  G+RG  G  G +G  G+ G+          A
Sbjct: 1254 DPGAIGAPGKTGP---VGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQ----------A 1300

Query: 348  GLSKPFPPPNIP 359
            G   P  PP +P
Sbjct: 1301 GPPGPVGPPGLP 1312



 Score =  187 bits (474), Expect = 2e-47
 Identities = 112/251 (44%), Positives = 134/251 (53%), Gaps = 24/251 (9%)

Query: 109 PGQKGEPGETGQPGPKGEAGN------LGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGV 162
           PG+ GE G+ G+ GP+G  G       LG  GPPG+ GP G RG  G +G KG  G QG 
Sbjct: 499 PGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGE 558

Query: 163 PGYPGK---PGAQGEPGP---------KGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGD 210
           PG PG+   PG QG PGP         KG +G  GL G+ G  G  G        G KG+
Sbjct: 559 PGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN 618

Query: 211 QGAMGSPGLHGGPGAKGEKGE---MGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGS 267
           QG  G  G  G PG +G KG     G KG  G+KG  G  G +G  G KG+ G  G  GS
Sbjct: 619 QGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGS 678

Query: 268 KGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGL---LGPTGPKGDIGNKGVRGPTGK 324
           +G+ G EG  GR G  G  G PG+ GEKG+LG PGL    G  GPKG +G  G  G +G+
Sbjct: 679 RGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGE 738

Query: 325 KGSRGFKGSKG 335
           KG+RG  G  G
Sbjct: 739 KGARGLSGKSG 749



 Score =  187 bits (474), Expect = 2e-47
 Identities = 111/262 (42%), Positives = 133/262 (50%), Gaps = 42/262 (16%)

Query: 110  GQKGEPGETGQPGPKGEAGN---LGIPGP---PGVVGPQGPRGYKGEKGLKGERGDQGVP 163
            G+ G+PGE G PGPKG  G+    G PGP   PG  GP G  G +G+ G KG+RG+ G P
Sbjct: 1154 GESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEP 1213

Query: 164  GYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSP------ 217
            G PG PG  GE GP G  G  G  G  G +G +G       KG KGD GA+G+P      
Sbjct: 1214 GQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGG------KGAKGDPGAIGAPGKTGPV 1267

Query: 218  ------------GLHGGPGAKGEKGEMGEKGEMGDKGCCGD------SGERGGKGQKGEG 259
                        GL G PG+ G++G  G  G+ G  G  G        G+ G KG+KG  
Sbjct: 1268 GPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHP 1327

Query: 260  GM------KGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDI 313
            G+       GE+G KGD G+ G  G  G  G  G PG  G  G  GPPGL GP GPKG  
Sbjct: 1328 GLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAK 1387

Query: 314  GNKGVRGPTGKKGSRGFKGSKG 335
            G  G  GP G+KG +G  G  G
Sbjct: 1388 GATGPGGPKGEKGVQGPPGHPG 1409



 Score =  186 bits (473), Expect = 3e-47
 Identities = 115/285 (40%), Positives = 130/285 (45%), Gaps = 32/285 (11%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGE------------ 156
           PG++G PG  G  GP G  G LG PGP GV G  G RG KG KG KGE            
Sbjct: 607 PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGV 666

Query: 157 RGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGS 216
           +GD+G  G PG  G  G  GPKG  G  G  G  G  G KG        G  G QG  GS
Sbjct: 667 KGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGS 726

Query: 217 PGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGK 276
            G  G PGA GEKG  G  G+ G +G  G +G RG +G +G  G  G KG+ G  G  G 
Sbjct: 727 LGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGP 786

Query: 277 SGRNGLPGAKGDPGIKGEKGELGPP------------------GLLGPTGPKGDIGNKGV 318
            G  GLPG +G  G  G KG  GPP                  G  GP GP G +G +G 
Sbjct: 787 PGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGA 846

Query: 319 RGPTGKKGSRGFKGSKGELAR--VPRSAFSAGLSKPFPPPNIPIK 361
            G TG  G RG  G  G      +P +A   G      PP  P K
Sbjct: 847 AGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGK 891



 Score =  186 bits (473), Expect = 3e-47
 Identities = 110/249 (44%), Positives = 129/249 (51%), Gaps = 16/249 (6%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQ------GPRGYKGEKGLKGERGDQGV 162
            PG+ G PG  GQ G  G  G  G PGPPGVVGPQ      GP G +G  G  G  G+QG+
Sbjct: 811  PGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGL 870

Query: 163  PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
            PG  GK G +G+PGP G  G  G  G++G  G +G        G  G  G  G+ G  G 
Sbjct: 871  PGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERG------LPGTAGGPGLKGNEGPSGP 924

Query: 223  PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGL 282
            PG  G  GE G  G  G  G  G  G +G  G  GE G+ GEKG  G +G +G  G  GL
Sbjct: 925  PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGL 984

Query: 283  PGAKGDPGIKGE---KGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGEL-A 338
            PG  G PG+ GE   KGE+G PG  G  G KG+ G  G  GP G  G  G  G+ GE  A
Sbjct: 985  PGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGA 1044

Query: 339  RVPRSAFSA 347
            R P+  F A
Sbjct: 1045 RGPQGHFGA 1053



 Score =  186 bits (472), Expect = 4e-47
 Identities = 103/251 (41%), Positives = 135/251 (53%), Gaps = 24/251 (9%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           G  G  G TG+PGP G+ G+ G+ G  G +GPQGPRG +G  G  G+ G +G  G  G  
Sbjct: 401 GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGAR 460

Query: 170 GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGN------CTKGEKGDQGAM--------- 214
           G  G+PG KGD+G  GL G+ G+KG +GDT            GE+GD G +         
Sbjct: 461 GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 520

Query: 215 ---------GSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEK 265
                    G PG+ G PG +G  G  G KG +G +G  G  G++G  G +G  G +G  
Sbjct: 521 GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAI 580

Query: 266 GSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKK 325
           G  G+ G +GK G  G+PG+ G PG  G++G  G  G  GP+GP+G +G  G RG  G  
Sbjct: 581 GPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVD 640

Query: 326 GSRGFKGSKGE 336
           G RG KG KGE
Sbjct: 641 GIRGLKGHKGE 651



 Score =  185 bits (470), Expect = 7e-47
 Identities = 109/270 (40%), Positives = 133/270 (49%), Gaps = 42/270 (15%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGP---RGYKGEK---------GLKGE 156
            PG  G PGE G PG  G+ G  G PGPPG  G  GP   RG+ GE+         GLKG 
Sbjct: 859  PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 918

Query: 157  RGDQGVPGYPGKPGAQ------------GEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCT 204
             G  G PG  G PG +            G PGP+G  G  G  GV G+KG  G T  +  
Sbjct: 919  EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGV 978

Query: 205  KGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDK------------------GCCGD 246
            +G  G  G  G PG+ G  G KGE G+ G+KG  G+K                  G  G 
Sbjct: 979  QGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGA 1038

Query: 247  SGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGP 306
             GE G +G +G  G KG++G++G +G  G  G  GLPG  G+ G  G+ G +GPPG  GP
Sbjct: 1039 DGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGP 1098

Query: 307  TGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
             GP G  G  G +GP G  G+ G  G KGE
Sbjct: 1099 RGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1128



 Score =  184 bits (468), Expect = 1e-46
 Identities = 107/250 (42%), Positives = 132/250 (52%), Gaps = 27/250 (10%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGY---KGEKGLKGERGDQGVPG 164
            VPG+KG  G TG+ G +G  G  G  GPPGV G  G +G     G+KG KG +G+ G PG
Sbjct: 963  VPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPG 1022

Query: 165  YPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPG 224
             PG  G  G+PG  G  G  G  G +G  G+KGD      +G +G  G  G  GL G PG
Sbjct: 1023 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGD------EGTRGFNGPPGPIGLQGLPG 1076

Query: 225  AKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPG 284
              GEKGE G+ G MG  G  G  G  G  G  G  G  G  G+ G  G +G+ G +G PG
Sbjct: 1077 PSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPG 1136

Query: 285  AKGDPGIK------GEKGELGPPGLLGPTGPKGDIGNKGVR------------GPTGKKG 326
             +G+PG+K      GEKGE G PG  GP GPKG  G+ G +            GP G+ G
Sbjct: 1137 IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGG 1196

Query: 327  SRGFKGSKGE 336
             RG  G+KG+
Sbjct: 1197 PRGQDGAKGD 1206



 Score =  181 bits (459), Expect = 1e-45
 Identities = 106/264 (40%), Positives = 135/264 (51%), Gaps = 14/264 (5%)

Query: 110 GQKGEPGETGQPGPKG---EAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYP 166
           G KG  G TG PGP G   E G LG+PG PG  G QGP+G  G  G  G  G++G  G  
Sbjct: 686 GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLS 745

Query: 167 GKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAK 226
           GK G +GE GP G +G  G  G  G+ G+KG + G+   G  G++G  G  G +G PG K
Sbjct: 746 GKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK 805

Query: 227 GEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAK 286
           G  G  G+ G  G  G  G+ G +G  G  G  G+ G +G+ G++G  G+ G  G PG  
Sbjct: 806 GPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPP 865

Query: 287 GDPGI------KGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGEL--- 337
           G+ G+      +G KG+ GPPG  G  GP G  G  G RG  G  G  G KG++G     
Sbjct: 866 GEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPP 925

Query: 338 --ARVPRSAFSAGLSKPFPPPNIP 359
             A  P    +AG   P  PP  P
Sbjct: 926 GPAGSPGERGAAGSGGPIGPPGRP 949



 Score =  180 bits (457), Expect = 2e-45
 Identities = 106/239 (44%), Positives = 123/239 (51%), Gaps = 15/239 (6%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
            G  G PG  G PG +G AG+ G  GPPG  GPQGP G  GEKG+ GE+G  G  G  G  
Sbjct: 920  GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 979

Query: 170  GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSP---GLHGGPGAK 226
            G  G PGP G  G   + G  G KG  GD     TKG KG+ G  G P   G  G PGA 
Sbjct: 980  GPVGLPGPAGPPG---VAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAA 1036

Query: 227  GEKGEMGEKGEMGDKGCCGDSGERGGKGQKGE---GGMKGEKGSKGDSGMEGKSGRNGLP 283
            G  GE G +G  G  G  GD G RG  G  G     G+ G  G KG++G  G  G  G P
Sbjct: 1037 GADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPP 1096

Query: 284  GAKGDPGIKGEKGELGPPGLLGPTGP------KGDIGNKGVRGPTGKKGSRGFKGSKGE 336
            G +G  G  G  G  GPPG +G  GP       G+ G+ G++G  G KG RG +G KGE
Sbjct: 1097 GPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGE 1155



 Score =  179 bits (453), Expect = 6e-45
 Identities = 103/243 (42%), Positives = 125/243 (51%), Gaps = 15/243 (6%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQG------PRGYKGEKGLKGERGDQG 161
           +PG  G  G  G  GPKG  G  G PGPPG  G  G      P+G  G  G KG +G  G
Sbjct: 534 IPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPG 593

Query: 162 VPGYPGK---PGAQGEPGPKGDKGNIGLGGVK------GQKGSKGDTCGNCTKGEKGDQG 212
           +PG PG    PG  G+ GP G KGN G  G +      G +G KG       KG KG++G
Sbjct: 594 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 653

Query: 213 AMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSG 272
             G PG  G  G KG++GE+G  G  G+ G  G  G  G  G  G  G+ GEKG  G  G
Sbjct: 654 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 713

Query: 273 MEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKG 332
           + G  GR G  G+ G PG  G  GE G  GL G +GP+G+ G  G RG  G +G+ G  G
Sbjct: 714 LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG 773

Query: 333 SKG 335
           +KG
Sbjct: 774 AKG 776



 Score =  176 bits (445), Expect = 5e-44
 Identities = 103/239 (43%), Positives = 117/239 (48%), Gaps = 15/239 (6%)

Query: 110  GQKGEPGETGQPGPKGE---AGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYP 166
            G  G PGE G PGP+G     G  G PGPPG  G  G  G +GE G +G+ G  G PG  
Sbjct: 782  GPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVV 841

Query: 167  GKPGAQGE---------PGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSP 217
            G  GA GE         PGP G  G  GL G  G++G+KGD       G+ G  G  G P
Sbjct: 842  GPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFP 901

Query: 218  GLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKS 277
            G  G PG  G  G  G +G  G  G  G  GERG     G GG  G  G  G  G  G +
Sbjct: 902  GERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGA---AGSGGPIGPPGRPGPQGPPGAA 958

Query: 278  GRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
            G  G+PG KG  G  G  G  GP GL GP GP G  G  G +G  G  G +G KG+KGE
Sbjct: 959  GEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE 1017



 Score =  172 bits (436), Expect = 6e-43
 Identities = 104/265 (39%), Positives = 124/265 (46%), Gaps = 16/265 (6%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPG---VVGPQGPRGYKGEKGLKGERGDQGVPGYP 166
            GQ+G  G TG+ G KG +G  G  GPPG   + GPQGP G+ G KG  G  G  G+PG+P
Sbjct: 761  GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHP 820

Query: 167  GK------------PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAM 214
            G+            PG  G  GP+G  G  G  G +G  G  G        G  G +G  
Sbjct: 821  GQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTK 880

Query: 215  GSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGME 274
            G PG  G PG  G  G  G  GE G  G  G  G +G +G  G  G  G  G +G +G  
Sbjct: 881  GDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSG 940

Query: 275  GKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSK 334
            G  G  G PG +G PG  GEKG  G  G +GPTG  G  G  G+ GP G  G  G  G K
Sbjct: 941  GPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDK 1000

Query: 335  GELARVPRSAFSAGLSKPFPPPNIP 359
            GE+   P    + G      PP  P
Sbjct: 1001 GEVGD-PGQKGTKGNKGEHGPPGPP 1024



 Score =  171 bits (433), Expect = 1e-42
 Identities = 104/256 (40%), Positives = 124/256 (48%), Gaps = 13/256 (5%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRG------YKGEKGLKGERGDQGVP 163
           G  G  GE G  GPKG  G  G PGPPG++G +G  G      Y G +G KG  G  G P
Sbjct: 674 GVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFP 733

Query: 164 GYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGP 223
           G  G+ GA+G  G  G +G  G  G +GQ+G +G T  +  KG  G  G  G PG  G P
Sbjct: 734 GASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLP 793

Query: 224 GAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLP 283
           G +G  G  G KG  G  G  G  G  G +G+ G  G  G  G  G  G +G +G  G  
Sbjct: 794 GPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPM 853

Query: 284 GAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRS 343
           G +G PG  G  GE G PG  G  G KGD G  G  G  G  G RGF G +G    +P +
Sbjct: 854 GERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERG----LPGT 909

Query: 344 AFSAGL---SKPFPPP 356
           A   GL     P  PP
Sbjct: 910 AGGPGLKGNEGPSGPP 925



 Score =  166 bits (420), Expect = 4e-41
 Identities = 102/265 (38%), Positives = 129/265 (48%), Gaps = 37/265 (13%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQG-----PRGYKGEKGLKGE------- 156
           PG +G PG  G PG +G  G  G+PG  G  GP G     P  +    G KG        
Sbjct: 327 PGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEA 386

Query: 157 -------------RGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNC 203
                        RG  G  GY G+PG  G+PG  G KG  G  G +G +G +G T    
Sbjct: 387 QAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPG 446

Query: 204 TKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKG 263
             G +G  GA G+ G+ G PG KG++G  G  G  G+KG  GD+G +G  G  GE G +G
Sbjct: 447 KAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERG 506

Query: 264 EKGSKGDSGMEGKSGRNGLPGAKGDPGI------------KGEKGELGPPGLLGPTGPKG 311
           + G  G  G+ G+SG  GL G KG PGI            +G KG LGP G  GP G +G
Sbjct: 507 DDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQG 566

Query: 312 DIGNKGVRGPTGKKGSRGFKGSKGE 336
             G +G+ GP G  G  G KG +G+
Sbjct: 567 TPGTQGLPGPQGAIGPHGEKGPQGK 591



 Score =  157 bits (398), Expect = 2e-38
 Identities = 115/366 (31%), Positives = 158/366 (43%), Gaps = 67/366 (18%)

Query: 16  IAGMNTIAKTTPHTKFTKKSEEREMPKGLKPSSGPPPEEEETLFTEMAEMAEPITK---P 72
           + G+    ++    +   +  +RE P+  +P       +++       +  EP ++   P
Sbjct: 211 VPGVQAAYESCEQKELECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQDPTP 270

Query: 73  SALDSVFGTATLSPFENFTLDPADFFLNCCDCCSPVPGQKGEPG--ETGQ--PGPKGEAG 128
              + +  ++ L P E     P             + G+KGEP   E G    GP G  G
Sbjct: 271 GEEEEILESSLLPPLEEAAHGPRG-----------LKGEKGEPAVLEPGMLVEGPPGPEG 319

Query: 129 NLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKPG------------------ 170
             G+ GPPG+ G  GP G  GE+G  G  G  G  G PG PG                  
Sbjct: 320 PAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGP 379

Query: 171 ------AQGEP----------GPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAM 214
                 AQ +           GP G  G  G  G  GQ GS G       KGE GD G  
Sbjct: 380 VVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPG------LKGESGDLGPQ 433

Query: 215 GSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGME 274
           G  G  G  G  G+ G  G  G  G +G  GD G +G +G  G  G+ GEKG +GD+G +
Sbjct: 434 GPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQ 493

Query: 275 GKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKG---VRGPTGKKGSRGFK 331
           G      LPG  G+ G +G+ GE+GP GL G +GP+G +G KG   + GP G +G  G +
Sbjct: 494 G------LPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQ 547

Query: 332 GSKGEL 337
           G KG L
Sbjct: 548 GPKGSL 553



 Score =  142 bits (359), Expect = 5e-34
 Identities = 84/199 (42%), Positives = 99/199 (49%), Gaps = 21/199 (10%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
            G  G PG  G+ G KG  G+ G  G PG  GP GP G  G+ G  G RG  G  G  G+P
Sbjct: 1235 GPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRP 1294

Query: 170  GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
            GA G+ GP G  G  GL G++G  G+KG+      KG  G  G +G P            
Sbjct: 1295 GATGQAGPPGPVGPPGLPGLRGDAGAKGE------KGHPGLIGLIGPP------------ 1336

Query: 230  GEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDP 289
               GE+GE GD+G  G  G  G KG+ G  G  G  G  G  G+ G +G  G  GA G  
Sbjct: 1337 ---GEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPG 1393

Query: 290  GIKGEKGELGPPGLLGPTG 308
            G KGEKG  GPPG  GP G
Sbjct: 1394 GPKGEKGVQGPPGHPGPPG 1412



 Score =  108 bits (270), Expect = 1e-23
 Identities = 66/162 (40%), Positives = 79/162 (48%), Gaps = 18/162 (11%)

Query: 109  PGQKGEPGET---------GQPGP------KGEAGNLGIPGPPGVVGPQGPRGYKGEKGL 153
            PG  G PG+T         G+PGP       G  G  G PG  G  GP GP G  G  GL
Sbjct: 1255 PGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGL 1314

Query: 154  KGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGA 213
            +G+ G +G  G+PG  G  G PG +G+KG+ GL G +G  G KG+       G  G  G 
Sbjct: 1315 RGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEM---GIPGASGPIGP 1371

Query: 214  MGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQ 255
             G PGL G  G KG KG  G  G  G+KG  G  G  G  G+
Sbjct: 1372 GGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGE 1413



 Score = 97.8 bits (242), Expect = 2e-20
 Identities = 57/135 (42%), Positives = 70/135 (51%), Gaps = 15/135 (11%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGL------KGERGDQGVP 163
            GQ+G PG TGQ GP G  G  G+PG  G  G +G +G+ G  GL      +GE+GD+G+P
Sbjct: 1289 GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1348

Query: 164  GYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGP 223
            G  G PG +GE G  G  G IG GG  G  G  G          KG +GA G  G  G  
Sbjct: 1349 GPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGP---------KGAKGATGPGGPKGEK 1399

Query: 224  GAKGEKGEMGEKGEM 238
            G +G  G  G  GE+
Sbjct: 1400 GVQGPPGHPGPPGEV 1414



 Score = 75.9 bits (185), Expect = 8e-14
 Identities = 40/84 (47%), Positives = 51/84 (60%), Gaps = 15/84 (17%)

Query: 109  PGQKGEPGETGQPGPKG---EAGNLGIPG---------PPGVVGPQGPRGYKGEK---GL 153
            PG++GE G+ G PGP+G   + G +GIPG         PPG+ GP GP+G KG     G 
Sbjct: 1336 PGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGP 1395

Query: 154  KGERGDQGVPGYPGKPGAQGEPGP 177
            KGE+G QG PG+PG PG   +P P
Sbjct: 1396 KGEKGVQGPPGHPGPPGEVIQPLP 1419



 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 55/159 (34%), Positives = 68/159 (42%), Gaps = 25/159 (15%)

Query: 205 KGEKGDQGAMGSPGL--HGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMK 262
           KGEKG+   +  PG+   G PG +G  G +G  G  G+ G  GD GERG  G+ G  G  
Sbjct: 296 KGEKGEPAVL-EPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSD 354

Query: 263 GEKGSKGDSGME----GKSGRNGLP------------------GAKGDPGIKGEKGELGP 300
           G  G  G S M     G  G +  P                    +G PG  G  G  GP
Sbjct: 355 GAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGP 414

Query: 301 PGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELAR 339
            G  G  G KG+ G+ G +GP G +G  G  G  G   R
Sbjct: 415 LGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGR 453



 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 34/92 (36%), Positives = 46/92 (50%), Gaps = 4/92 (4%)

Query: 264 EKGSKGDSGMEGKSGRNGL--PG--AKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVR 319
           E+ + G  G++G+ G   +  PG   +G PG +G  G +GPPG+ G  GP GD G +G  
Sbjct: 286 EEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPP 345

Query: 320 GPTGKKGSRGFKGSKGELARVPRSAFSAGLSK 351
           G  G  GS G  G  G    +P    S G  K
Sbjct: 346 GRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDK 377



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 32/85 (37%), Positives = 41/85 (48%), Gaps = 10/85 (11%)

Query: 285 AKGDPGIKGEKGELG--PPGLL--GPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARV 340
           A G  G+KGEKGE     PG+L  GP GP+G     G+ GP G +G+ G  G  GE    
Sbjct: 289 AHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGP---AGLIGPPGIQGNPGPVGDPGERGPP 345

Query: 341 PRSAFSAGLSKPFPPPN---IPIKF 362
            R+        P PP     +P +F
Sbjct: 346 GRAGLPGSDGAPGPPGTSLMLPFRF 370



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 28/80 (35%), Positives = 34/80 (42%), Gaps = 13/80 (16%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQG--------PRGYKGEKGLKGER-- 157
            +PG  G  G  G  GP G  G  G+ GPPG  GP G            K  + + G R  
Sbjct: 1377 LPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLM 1436

Query: 158  -GDQGVP--GYPGKPGAQGE 174
              D+ +P  G PG PG   E
Sbjct: 1437 QEDEAIPTGGAPGSPGGLEE 1456


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score =  195 bits (495), Expect = 9e-50
 Identities = 117/266 (43%), Positives = 141/266 (53%), Gaps = 25/266 (9%)

Query: 109  PGQKGEPGETGQPG---------PKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGD 159
            PG+KGEPGE+G PG         P+GE G  G  G PG  GP GP+G  G+ G KG  G 
Sbjct: 1102 PGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGP 1161

Query: 160  QGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGL 219
             G PG PG PG  G  G  G KG+ G  G  GQ GS G T  N   G  G +G  GSPG 
Sbjct: 1162 VGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGS 1221

Query: 220  HG---GPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKG---EGGMKGEKGSKGDSGM 273
             G   G GAKG+ G +G  G+ G  G  G +G+ G  G +G     G +G  G+ G +G 
Sbjct: 1222 EGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGP 1281

Query: 274  EGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGS 333
             G  G  GLPG +GD G KGEKG    PGL+G  GP G+ G KG RG  G +GS G KG 
Sbjct: 1282 PGPVGPPGLPGLRGDAGAKGEKGH---PGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGE 1338

Query: 334  KGELARVPRSAFSAGLSKPFPPPNIP 359
             G    +P ++   G   P  PP +P
Sbjct: 1339 MG----IPGASGPIG---PGGPPGLP 1357



 Score =  193 bits (490), Expect = 3e-49
 Identities = 104/248 (41%), Positives = 128/248 (51%), Gaps = 6/248 (2%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
           +PG  G PG  G+ GP G  GN G  GP G +G  GPRG KG  G++G +G +G  G  G
Sbjct: 576 MPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDG 635

Query: 168 KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKG 227
            PG +G+ G KGD+G +G+ G +G+ G +G        G+ G  G MG  G  G PG  G
Sbjct: 636 FPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPG 695

Query: 228 EKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKG 287
             G  G KG +G  G  G SGE+G +G  G+ G +GE+G  G  G  G  G  G  GAKG
Sbjct: 696 YPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKG 755

Query: 288 DPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSA 347
             G  G  G  G  GL GP GP G  G KG  GP GK G  G  G +GE+       F  
Sbjct: 756 TSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEV------GFQG 809

Query: 348 GLSKPFPP 355
               P PP
Sbjct: 810 KTGPPGPP 817



 Score =  192 bits (488), Expect = 6e-49
 Identities = 112/276 (40%), Positives = 134/276 (48%), Gaps = 34/276 (12%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGP------------QGPRGYKGEKGLKGER 157
            G KGE G+ GQ G KG  G  G PGPPG +GP             G RG +G  G KG+ 
Sbjct: 977  GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1036

Query: 158  GDQGVPGYPGKPGAQGEPGPKGDKGN------------------IGLGGVKGQKGSKGDT 199
            G +G  G PG  G QG PGP G+KG                    G  G  G +G  G  
Sbjct: 1037 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGV 1096

Query: 200  CGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEG 259
                  GEKG+ G  GSPG+ G PG KG +GE GEKGE G  G  G  G +G  G  G  
Sbjct: 1097 GNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPK 1156

Query: 260  GMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVR 319
            G  G  G  GD G  G+ G  G  GAKGD G  GE G+ G PG  G  GP G +G +G  
Sbjct: 1157 GNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPA 1216

Query: 320  GPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPP 355
            G  G +G +G KG+KG+    P +  + G + P  P
Sbjct: 1217 GSPGSEGRQGGKGAKGD----PGAIGAPGKTGPVGP 1248



 Score =  191 bits (486), Expect = 1e-48
 Identities = 100/229 (43%), Positives = 126/229 (55%), Gaps = 6/229 (2%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK- 168
           G  G  GE G PG +G  G  G+PGP G +GP G +G +G+ GL G  G  G PG+PGK 
Sbjct: 530 GSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKE 589

Query: 169 --PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAK 226
             PG +G  GP G +G +G  G +G KG  G       KG KG++G  G PG  G  G K
Sbjct: 590 GPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGI---RGLKGHKGEKGEDGFPGFKGDIGVK 646

Query: 227 GEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAK 286
           G++GE+G  G  G+ G  G  G  G  G  G  G+ GEKG  G  G+ G  GR G  G+ 
Sbjct: 647 GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL 706

Query: 287 GDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
           G PG  G  GE G  GL G +GP+G+ G  G RG  G +G+ G  G+KG
Sbjct: 707 GFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKG 755



 Score =  189 bits (480), Expect = 5e-48
 Identities = 110/250 (44%), Positives = 140/250 (56%), Gaps = 27/250 (10%)

Query: 109 PGQKGE------PGETGQPGPKGEAGNLGIPGPPGVVGPQG------PRGYKGEKGLKGE 156
           PG KG+      PG  G+ G +G+ G  G+PGPPG  G +G      PRG  GE G +G 
Sbjct: 445 PGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGL 504

Query: 157 RGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAM-- 214
            G +G PG PG PG +G  GP+G KG++G  G  G  G +G T G  T+G  G QGA+  
Sbjct: 505 LGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQG-TPG--TQGLPGPQGAIGP 561

Query: 215 -------GSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGS 267
                  G PGL G PG+ G  G  G++G  G KG  G SG +G  G  G  G+KG  G 
Sbjct: 562 HGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGI 621

Query: 268 KGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGS 327
           +G  G +G+ G +G PG KGD G+KG++GE+G PG  G  GP+G    KG  GPTG  G 
Sbjct: 622 RGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGP---KGRTGPTGDPGP 678

Query: 328 RGFKGSKGEL 337
            G  G KG+L
Sbjct: 679 PGLMGEKGKL 688



 Score =  187 bits (475), Expect = 2e-47
 Identities = 106/252 (42%), Positives = 126/252 (50%), Gaps = 13/252 (5%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
            +PG  GE GETG  GP G  G  G  GP G  G  GP+G  G  G  G  G++G PG  G
Sbjct: 1053 LPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESG 1112

Query: 168  KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKG 227
             PG QGEPG KG +G  G  G  GQ G  G        G+ G +G  G  G  G PG  G
Sbjct: 1113 SPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG 1172

Query: 228  EKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKG 287
            E G  G+ G  GD+G  G+ G+ G  G  GE G  G  G +G +G  G  GR G  GAKG
Sbjct: 1173 EGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKG 1232

Query: 288  DPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSA 347
            DPG  G  G+ GP   +GP GP G  G  G+RG  G  G +G  G+ G+          A
Sbjct: 1233 DPGAIGAPGKTGP---VGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQ----------A 1279

Query: 348  GLSKPFPPPNIP 359
            G   P  PP +P
Sbjct: 1280 GPPGPVGPPGLP 1291



 Score =  187 bits (474), Expect = 2e-47
 Identities = 112/251 (44%), Positives = 134/251 (53%), Gaps = 24/251 (9%)

Query: 109 PGQKGEPGETGQPGPKGEAGN------LGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGV 162
           PG+ GE G+ G+ GP+G  G       LG  GPPG+ GP G RG  G +G KG  G QG 
Sbjct: 478 PGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGE 537

Query: 163 PGYPGK---PGAQGEPGP---------KGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGD 210
           PG PG+   PG QG PGP         KG +G  GL G+ G  G  G        G KG+
Sbjct: 538 PGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN 597

Query: 211 QGAMGSPGLHGGPGAKGEKGE---MGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGS 267
           QG  G  G  G PG +G KG     G KG  G+KG  G  G +G  G KG+ G  G  GS
Sbjct: 598 QGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGS 657

Query: 268 KGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGL---LGPTGPKGDIGNKGVRGPTGK 324
           +G+ G EG  GR G  G  G PG+ GEKG+LG PGL    G  GPKG +G  G  G +G+
Sbjct: 658 RGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGE 717

Query: 325 KGSRGFKGSKG 335
           KG+RG  G  G
Sbjct: 718 KGARGLSGKSG 728



 Score =  187 bits (474), Expect = 2e-47
 Identities = 111/262 (42%), Positives = 133/262 (50%), Gaps = 42/262 (16%)

Query: 110  GQKGEPGETGQPGPKGEAGN---LGIPGP---PGVVGPQGPRGYKGEKGLKGERGDQGVP 163
            G+ G+PGE G PGPKG  G+    G PGP   PG  GP G  G +G+ G KG+RG+ G P
Sbjct: 1133 GESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEP 1192

Query: 164  GYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSP------ 217
            G PG PG  GE GP G  G  G  G  G +G +G       KG KGD GA+G+P      
Sbjct: 1193 GQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGG------KGAKGDPGAIGAPGKTGPV 1246

Query: 218  ------------GLHGGPGAKGEKGEMGEKGEMGDKGCCGD------SGERGGKGQKGEG 259
                        GL G PG+ G++G  G  G+ G  G  G        G+ G KG+KG  
Sbjct: 1247 GPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHP 1306

Query: 260  GM------KGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDI 313
            G+       GE+G KGD G+ G  G  G  G  G PG  G  G  GPPGL GP GPKG  
Sbjct: 1307 GLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAK 1366

Query: 314  GNKGVRGPTGKKGSRGFKGSKG 335
            G  G  GP G+KG +G  G  G
Sbjct: 1367 GATGPGGPKGEKGVQGPPGHPG 1388



 Score =  186 bits (473), Expect = 3e-47
 Identities = 115/285 (40%), Positives = 130/285 (45%), Gaps = 32/285 (11%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGE------------ 156
           PG++G PG  G  GP G  G LG PGP GV G  G RG KG KG KGE            
Sbjct: 586 PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGV 645

Query: 157 RGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGS 216
           +GD+G  G PG  G  G  GPKG  G  G  G  G  G KG        G  G QG  GS
Sbjct: 646 KGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGS 705

Query: 217 PGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGK 276
            G  G PGA GEKG  G  G+ G +G  G +G RG +G +G  G  G KG+ G  G  G 
Sbjct: 706 LGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGP 765

Query: 277 SGRNGLPGAKGDPGIKGEKGELGPP------------------GLLGPTGPKGDIGNKGV 318
            G  GLPG +G  G  G KG  GPP                  G  GP GP G +G +G 
Sbjct: 766 PGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGA 825

Query: 319 RGPTGKKGSRGFKGSKGELAR--VPRSAFSAGLSKPFPPPNIPIK 361
            G TG  G RG  G  G      +P +A   G      PP  P K
Sbjct: 826 AGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGK 870



 Score =  186 bits (473), Expect = 3e-47
 Identities = 110/249 (44%), Positives = 129/249 (51%), Gaps = 16/249 (6%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQ------GPRGYKGEKGLKGERGDQGV 162
            PG+ G PG  GQ G  G  G  G PGPPGVVGPQ      GP G +G  G  G  G+QG+
Sbjct: 790  PGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGL 849

Query: 163  PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
            PG  GK G +G+PGP G  G  G  G++G  G +G        G  G  G  G+ G  G 
Sbjct: 850  PGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERG------LPGTAGGPGLKGNEGPSGP 903

Query: 223  PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGL 282
            PG  G  GE G  G  G  G  G  G +G  G  GE G+ GEKG  G +G +G  G  GL
Sbjct: 904  PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGL 963

Query: 283  PGAKGDPGIKGE---KGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGEL-A 338
            PG  G PG+ GE   KGE+G PG  G  G KG+ G  G  GP G  G  G  G+ GE  A
Sbjct: 964  PGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGA 1023

Query: 339  RVPRSAFSA 347
            R P+  F A
Sbjct: 1024 RGPQGHFGA 1032



 Score =  186 bits (472), Expect = 4e-47
 Identities = 103/251 (41%), Positives = 135/251 (53%), Gaps = 24/251 (9%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           G  G  G TG+PGP G+ G+ G+ G  G +GPQGPRG +G  G  G+ G +G  G  G  
Sbjct: 380 GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGAR 439

Query: 170 GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGN------CTKGEKGDQGAM--------- 214
           G  G+PG KGD+G  GL G+ G+KG +GDT            GE+GD G +         
Sbjct: 440 GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 499

Query: 215 ---------GSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEK 265
                    G PG+ G PG +G  G  G KG +G +G  G  G++G  G +G  G +G  
Sbjct: 500 GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAI 559

Query: 266 GSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKK 325
           G  G+ G +GK G  G+PG+ G PG  G++G  G  G  GP+GP+G +G  G RG  G  
Sbjct: 560 GPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVD 619

Query: 326 GSRGFKGSKGE 336
           G RG KG KGE
Sbjct: 620 GIRGLKGHKGE 630



 Score =  185 bits (470), Expect = 7e-47
 Identities = 109/270 (40%), Positives = 133/270 (49%), Gaps = 42/270 (15%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGP---RGYKGEKGL---------KGE 156
            PG  G PGE G PG  G+ G  G PGPPG  G  GP   RG+ GE+GL         KG 
Sbjct: 838  PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 897

Query: 157  RGDQGVPGYPGKPGAQG------------EPGPKGDKGNIGLGGVKGQKGSKGDTCGNCT 204
             G  G PG  G PG +G             PGP+G  G  G  GV G+KG  G T  +  
Sbjct: 898  EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGV 957

Query: 205  KGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKG------------------CCGD 246
            +G  G  G  G PG+ G  G KGE G+ G+KG  G+KG                    G 
Sbjct: 958  QGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGA 1017

Query: 247  SGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGP 306
             GE G +G +G  G KG++G++G +G  G  G  GLPG  G+ G  G+ G +GPPG  GP
Sbjct: 1018 DGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGP 1077

Query: 307  TGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
             GP G  G  G +GP G  G+ G  G KGE
Sbjct: 1078 RGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1107



 Score =  184 bits (468), Expect = 1e-46
 Identities = 107/250 (42%), Positives = 132/250 (52%), Gaps = 27/250 (10%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGY---KGEKGLKGERGDQGVPG 164
            VPG+KG  G TG+ G +G  G  G  GPPGV G  G +G     G+KG KG +G+ G PG
Sbjct: 942  VPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPG 1001

Query: 165  YPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPG 224
             PG  G  G+PG  G  G  G  G +G  G+KGD      +G +G  G  G  GL G PG
Sbjct: 1002 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGD------EGTRGFNGPPGPIGLQGLPG 1055

Query: 225  AKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPG 284
              GEKGE G+ G MG  G  G  G  G  G  G  G  G  G+ G  G +G+ G +G PG
Sbjct: 1056 PSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPG 1115

Query: 285  AKGDPGIK------GEKGELGPPGLLGPTGPKGDIGNKGVR------------GPTGKKG 326
             +G+PG+K      GEKGE G PG  GP GPKG  G+ G +            GP G+ G
Sbjct: 1116 IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGG 1175

Query: 327  SRGFKGSKGE 336
             RG  G+KG+
Sbjct: 1176 PRGQDGAKGD 1185



 Score =  181 bits (459), Expect = 1e-45
 Identities = 106/264 (40%), Positives = 135/264 (51%), Gaps = 14/264 (5%)

Query: 110 GQKGEPGETGQPGPKG---EAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYP 166
           G KG  G TG PGP G   E G LG+PG PG  G QGP+G  G  G  G  G++G  G  
Sbjct: 665 GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLS 724

Query: 167 GKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAK 226
           GK G +GE GP G +G  G  G  G+ G+KG + G+   G  G++G  G  G +G PG K
Sbjct: 725 GKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK 784

Query: 227 GEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAK 286
           G  G  G+ G  G  G  G+ G +G  G  G  G+ G +G+ G++G  G+ G  G PG  
Sbjct: 785 GPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPP 844

Query: 287 GDPGI------KGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGEL--- 337
           G+ G+      +G KG+ GPPG  G  GP G  G  G RG  G  G  G KG++G     
Sbjct: 845 GEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPP 904

Query: 338 --ARVPRSAFSAGLSKPFPPPNIP 359
             A  P    +AG   P  PP  P
Sbjct: 905 GPAGSPGERGAAGSGGPIGPPGRP 928



 Score =  180 bits (457), Expect = 2e-45
 Identities = 106/239 (44%), Positives = 123/239 (51%), Gaps = 15/239 (6%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
            G  G PG  G PG +G AG+ G  GPPG  GPQGP G  GEKG+ GE+G  G  G  G  
Sbjct: 899  GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 958

Query: 170  GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSP---GLHGGPGAK 226
            G  G PGP G  G   + G  G KG  GD     TKG KG+ G  G P   G  G PGA 
Sbjct: 959  GPVGLPGPAGPPG---VAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAA 1015

Query: 227  GEKGEMGEKGEMGDKGCCGDSGERGGKGQKGE---GGMKGEKGSKGDSGMEGKSGRNGLP 283
            G  GE G +G  G  G  GD G RG  G  G     G+ G  G KG++G  G  G  G P
Sbjct: 1016 GADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPP 1075

Query: 284  GAKGDPGIKGEKGELGPPGLLGPTGP------KGDIGNKGVRGPTGKKGSRGFKGSKGE 336
            G +G  G  G  G  GPPG +G  GP       G+ G+ G++G  G KG RG +G KGE
Sbjct: 1076 GPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGE 1134



 Score =  176 bits (445), Expect = 5e-44
 Identities = 103/239 (43%), Positives = 117/239 (48%), Gaps = 15/239 (6%)

Query: 110 GQKGEPGETGQPGPKGE---AGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYP 166
           G  G PGE G PGP+G     G  G PGPPG  G  G  G +GE G +G+ G  G PG  
Sbjct: 761 GPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVV 820

Query: 167 GKPGAQGE---------PGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSP 217
           G  GA GE         PGP G  G  GL G  G++G+KGD       G+ G  G  G P
Sbjct: 821 GPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFP 880

Query: 218 GLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKS 277
           G  G PG  G  G  G +G  G  G  G  GERG     G GG  G  G  G  G  G +
Sbjct: 881 GERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGA---AGSGGPIGPPGRPGPQGPPGAA 937

Query: 278 GRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
           G  G+PG KG  G  G  G  GP GL GP GP G  G  G +G  G  G +G KG+KGE
Sbjct: 938 GEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE 996



 Score =  172 bits (436), Expect = 6e-43
 Identities = 104/265 (39%), Positives = 124/265 (46%), Gaps = 16/265 (6%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPG---VVGPQGPRGYKGEKGLKGERGDQGVPGYP 166
            GQ+G  G TG+ G KG +G  G  GPPG   + GPQGP G+ G KG  G  G  G+PG+P
Sbjct: 740  GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHP 799

Query: 167  GK------------PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAM 214
            G+            PG  G  GP+G  G  G  G +G  G  G        G  G +G  
Sbjct: 800  GQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTK 859

Query: 215  GSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGME 274
            G PG  G PG  G  G  G  GE G  G  G  G +G +G  G  G  G  G +G +G  
Sbjct: 860  GDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSG 919

Query: 275  GKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSK 334
            G  G  G PG +G PG  GEKG  G  G +GPTG  G  G  G+ GP G  G  G  G K
Sbjct: 920  GPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDK 979

Query: 335  GELARVPRSAFSAGLSKPFPPPNIP 359
            GE+   P    + G      PP  P
Sbjct: 980  GEVGD-PGQKGTKGNKGEHGPPGPP 1003



 Score =  171 bits (433), Expect = 1e-42
 Identities = 104/256 (40%), Positives = 124/256 (48%), Gaps = 13/256 (5%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRG------YKGEKGLKGERGDQGVP 163
           G  G  GE G  GPKG  G  G PGPPG++G +G  G      Y G +G KG  G  G P
Sbjct: 653 GVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFP 712

Query: 164 GYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGP 223
           G  G+ GA+G  G  G +G  G  G +GQ+G +G T  +  KG  G  G  G PG  G P
Sbjct: 713 GASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLP 772

Query: 224 GAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLP 283
           G +G  G  G KG  G  G  G  G  G +G+ G  G  G  G  G  G +G +G  G  
Sbjct: 773 GPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPM 832

Query: 284 GAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRS 343
           G +G PG  G  GE G PG  G  G KGD G  G  G  G  G RGF G +G    +P +
Sbjct: 833 GERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERG----LPGT 888

Query: 344 AFSAGL---SKPFPPP 356
           A   GL     P  PP
Sbjct: 889 AGGPGLKGNEGPSGPP 904



 Score =  166 bits (420), Expect = 4e-41
 Identities = 102/265 (38%), Positives = 129/265 (48%), Gaps = 37/265 (13%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQG-----PRGYKGEKGLKGE------- 156
           PG +G PG  G PG +G  G  G+PG  G  GP G     P  +    G KG        
Sbjct: 306 PGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEA 365

Query: 157 -------------RGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNC 203
                        RG  G  GY G+PG  G+PG  G KG  G  G +G +G +G T    
Sbjct: 366 QAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPG 425

Query: 204 TKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKG 263
             G +G  GA G+ G+ G PG KG++G  G  G  G+KG  GD+G +G  G  GE G +G
Sbjct: 426 KAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERG 485

Query: 264 EKGSKGDSGMEGKSGRNGLPGAKGDPGI------------KGEKGELGPPGLLGPTGPKG 311
           + G  G  G+ G+SG  GL G KG PGI            +G KG LGP G  GP G +G
Sbjct: 486 DDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQG 545

Query: 312 DIGNKGVRGPTGKKGSRGFKGSKGE 336
             G +G+ GP G  G  G KG +G+
Sbjct: 546 TPGTQGLPGPQGAIGPHGEKGPQGK 570



 Score =  153 bits (387), Expect = 3e-37
 Identities = 103/269 (38%), Positives = 126/269 (46%), Gaps = 53/269 (19%)

Query: 110 GQKGEPG--ETGQ--PGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGY 165
           G+KGEP   E G    GP G  G  G+ GPPG+ G  GP G  GE+G  G  G  G  G 
Sbjct: 276 GEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGA 335

Query: 166 PGKPG------------------------AQGEP----------GPKGDKGNIGLGGVKG 191
           PG PG                        AQ +           GP G  G  G  G  G
Sbjct: 336 PGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLG 395

Query: 192 QKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERG 251
           Q GS G       KGE GD G  G  G  G  G  G+ G  G  G  G +G  GD G +G
Sbjct: 396 QPGSPG------LKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKG 449

Query: 252 GKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKG 311
            +G  G  G+ GEKG +GD+G +G      LPG  G+ G +G+ GE+GP GL G +GP+G
Sbjct: 450 DRGFDGLPGLPGEKGHRGDTGAQG------LPGPPGEDGERGDDGEIGPRGLPGESGPRG 503

Query: 312 DIGNKG---VRGPTGKKGSRGFKGSKGEL 337
            +G KG   + GP G +G  G +G KG L
Sbjct: 504 LLGPKGPPGIPGPPGVRGMDGPQGPKGSL 532



 Score =  142 bits (359), Expect = 5e-34
 Identities = 84/199 (42%), Positives = 99/199 (49%), Gaps = 21/199 (10%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
            G  G PG  G+ G KG  G+ G  G PG  GP GP G  G+ G  G RG  G  G  G+P
Sbjct: 1214 GPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRP 1273

Query: 170  GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
            GA G+ GP G  G  GL G++G  G+KG+      KG  G  G +G P            
Sbjct: 1274 GATGQAGPPGPVGPPGLPGLRGDAGAKGE------KGHPGLIGLIGPP------------ 1315

Query: 230  GEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDP 289
               GE+GE GD+G  G  G  G KG+ G  G  G  G  G  G+ G +G  G  GA G  
Sbjct: 1316 ---GEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPG 1372

Query: 290  GIKGEKGELGPPGLLGPTG 308
            G KGEKG  GPPG  GP G
Sbjct: 1373 GPKGEKGVQGPPGHPGPPG 1391



 Score =  138 bits (347), Expect = 1e-32
 Identities = 93/249 (37%), Positives = 113/249 (45%), Gaps = 36/249 (14%)

Query: 143 GPRGYKGEKG----------LKGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQ 192
           GPRG KGEKG          ++G  G +G  G  G PG QG PGP GD G  G  G  G 
Sbjct: 270 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 329

Query: 193 KGSKGDTCGNCTK-----------GEKGDQGA-----------MGSPGLHGGPGAKGEKG 230
            GS G      T            G+KG   A                L G PG  G  G
Sbjct: 330 PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTG 389

Query: 231 EMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPG 290
             G  G+ G  G  G+SG+ G +G +G  G+ G  G  G  G  G  G  G+P   GDPG
Sbjct: 390 RPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMP---GDPG 446

Query: 291 IKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLS 350
           +KG++G  G PGL G  G +GD G +G+ GP G+ G RG  G  G    +P  +   GL 
Sbjct: 447 VKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRG-LPGESGPRGLL 505

Query: 351 KPFPPPNIP 359
            P  PP IP
Sbjct: 506 GPKGPPGIP 514



 Score =  108 bits (270), Expect = 1e-23
 Identities = 66/162 (40%), Positives = 79/162 (48%), Gaps = 18/162 (11%)

Query: 109  PGQKGEPGET---------GQPGP------KGEAGNLGIPGPPGVVGPQGPRGYKGEKGL 153
            PG  G PG+T         G+PGP       G  G  G PG  G  GP GP G  G  GL
Sbjct: 1234 PGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGL 1293

Query: 154  KGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGA 213
            +G+ G +G  G+PG  G  G PG +G+KG+ GL G +G  G KG+       G  G  G 
Sbjct: 1294 RGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEM---GIPGASGPIGP 1350

Query: 214  MGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQ 255
             G PGL G  G KG KG  G  G  G+KG  G  G  G  G+
Sbjct: 1351 GGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGE 1392



 Score = 97.8 bits (242), Expect = 2e-20
 Identities = 57/135 (42%), Positives = 70/135 (51%), Gaps = 15/135 (11%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGL------KGERGDQGVP 163
            GQ+G PG TGQ GP G  G  G+PG  G  G +G +G+ G  GL      +GE+GD+G+P
Sbjct: 1268 GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1327

Query: 164  GYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGP 223
            G  G PG +GE G  G  G IG GG  G  G  G          KG +GA G  G  G  
Sbjct: 1328 GPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGP---------KGAKGATGPGGPKGEK 1378

Query: 224  GAKGEKGEMGEKGEM 238
            G +G  G  G  GE+
Sbjct: 1379 GVQGPPGHPGPPGEV 1393



 Score = 75.9 bits (185), Expect = 8e-14
 Identities = 40/84 (47%), Positives = 51/84 (60%), Gaps = 15/84 (17%)

Query: 109  PGQKGEPGETGQPGPKG---EAGNLGIPG---------PPGVVGPQGPRGYKGEK---GL 153
            PG++GE G+ G PGP+G   + G +GIPG         PPG+ GP GP+G KG     G 
Sbjct: 1315 PGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGP 1374

Query: 154  KGERGDQGVPGYPGKPGAQGEPGP 177
            KGE+G QG PG+PG PG   +P P
Sbjct: 1375 KGEKGVQGPPGHPGPPGEVIQPLP 1398



 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 64/212 (30%), Positives = 84/212 (39%), Gaps = 19/212 (8%)

Query: 154 KGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGS-KGDTCGNCTKGEKGDQG 212
           + +R  Q  P    +P  Q EP  +   G  GL G KG+    +         G +G  G
Sbjct: 243 RAQRSPQQQPSRLHRPQNQ-EPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAG 301

Query: 213 AMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGK----GQKGEGGMKGEKG-- 266
            +G PG+ G PG  G+ GE G  G  G  G  G  G  G       + G GG  G+KG  
Sbjct: 302 LIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--GDKGPV 359

Query: 267 ---SKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTG 323
               +  +    +  R  L G  G  G  G  G LG PG  G  G  GD+G      P G
Sbjct: 360 VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLG------PQG 413

Query: 324 KKGSRGFKGSKGELARVPRSAFSAGLSKPFPP 355
            +G +G  G  G+  R  R+        P  P
Sbjct: 414 PRGPQGLTGPPGKAGRRGRAGADGARGMPGDP 445



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 32/85 (37%), Positives = 41/85 (48%), Gaps = 10/85 (11%)

Query: 285 AKGDPGIKGEKGELG--PPGLL--GPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARV 340
           A G  G+KGEKGE     PG+L  GP GP+G     G+ GP G +G+ G  G  GE    
Sbjct: 268 AHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGP---AGLIGPPGIQGNPGPVGDPGERGPP 324

Query: 341 PRSAFSAGLSKPFPPPN---IPIKF 362
            R+        P PP     +P +F
Sbjct: 325 GRAGLPGSDGAPGPPGTSLMLPFRF 349



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 28/80 (35%), Positives = 34/80 (42%), Gaps = 13/80 (16%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQG--------PRGYKGEKGLKGER-- 157
            +PG  G  G  G  GP G  G  G+ GPPG  GP G            K  + + G R  
Sbjct: 1356 LPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLM 1415

Query: 158  -GDQGVP--GYPGKPGAQGE 174
              D+ +P  G PG PG   E
Sbjct: 1416 QEDEAIPTGGAPGSPGGLEE 1435


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score =  195 bits (495), Expect = 9e-50
 Identities = 117/266 (43%), Positives = 141/266 (53%), Gaps = 25/266 (9%)

Query: 109  PGQKGEPGETGQPG---------PKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGD 159
            PG+KGEPGE+G PG         P+GE G  G  G PG  GP GP+G  G+ G KG  G 
Sbjct: 1209 PGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGP 1268

Query: 160  QGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGL 219
             G PG PG PG  G  G  G KG+ G  G  GQ GS G T  N   G  G +G  GSPG 
Sbjct: 1269 VGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGS 1328

Query: 220  HG---GPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKG---EGGMKGEKGSKGDSGM 273
             G   G GAKG+ G +G  G+ G  G  G +G+ G  G +G     G +G  G+ G +G 
Sbjct: 1329 EGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGP 1388

Query: 274  EGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGS 333
             G  G  GLPG +GD G KGEKG    PGL+G  GP G+ G KG RG  G +GS G KG 
Sbjct: 1389 PGPVGPPGLPGLRGDAGAKGEKGH---PGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGE 1445

Query: 334  KGELARVPRSAFSAGLSKPFPPPNIP 359
             G    +P ++   G   P  PP +P
Sbjct: 1446 MG----IPGASGPIG---PGGPPGLP 1464



 Score =  193 bits (490), Expect = 3e-49
 Identities = 104/248 (41%), Positives = 128/248 (51%), Gaps = 6/248 (2%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
           +PG  G PG  G+ GP G  GN G  GP G +G  GPRG KG  G++G +G +G  G  G
Sbjct: 683 MPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDG 742

Query: 168 KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKG 227
            PG +G+ G KGD+G +G+ G +G+ G +G        G+ G  G MG  G  G PG  G
Sbjct: 743 FPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPG 802

Query: 228 EKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKG 287
             G  G KG +G  G  G SGE+G +G  G+ G +GE+G  G  G  G  G  G  GAKG
Sbjct: 803 YPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKG 862

Query: 288 DPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSA 347
             G  G  G  G  GL GP GP G  G KG  GP GK G  G  G +GE+       F  
Sbjct: 863 TSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEV------GFQG 916

Query: 348 GLSKPFPP 355
               P PP
Sbjct: 917 KTGPPGPP 924



 Score =  192 bits (488), Expect = 6e-49
 Identities = 112/276 (40%), Positives = 134/276 (48%), Gaps = 34/276 (12%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGP------------QGPRGYKGEKGLKGER 157
            G KGE G+ GQ G KG  G  G PGPPG +GP             G RG +G  G KG+ 
Sbjct: 1084 GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1143

Query: 158  GDQGVPGYPGKPGAQGEPGPKGDKGN------------------IGLGGVKGQKGSKGDT 199
            G +G  G PG  G QG PGP G+KG                    G  G  G +G  G  
Sbjct: 1144 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGV 1203

Query: 200  CGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEG 259
                  GEKG+ G  GSPG+ G PG KG +GE GEKGE G  G  G  G +G  G  G  
Sbjct: 1204 GNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPK 1263

Query: 260  GMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVR 319
            G  G  G  GD G  G+ G  G  GAKGD G  GE G+ G PG  G  GP G +G +G  
Sbjct: 1264 GNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPA 1323

Query: 320  GPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPP 355
            G  G +G +G KG+KG+    P +  + G + P  P
Sbjct: 1324 GSPGSEGRQGGKGAKGD----PGAIGAPGKTGPVGP 1355



 Score =  191 bits (486), Expect = 1e-48
 Identities = 100/229 (43%), Positives = 126/229 (55%), Gaps = 6/229 (2%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK- 168
           G  G  GE G PG +G  G  G+PGP G +GP G +G +G+ GL G  G  G PG+PGK 
Sbjct: 637 GSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKE 696

Query: 169 --PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAK 226
             PG +G  GP G +G +G  G +G KG  G       KG KG++G  G PG  G  G K
Sbjct: 697 GPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGI---RGLKGHKGEKGEDGFPGFKGDIGVK 753

Query: 227 GEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAK 286
           G++GE+G  G  G+ G  G  G  G  G  G  G+ GEKG  G  G+ G  GR G  G+ 
Sbjct: 754 GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL 813

Query: 287 GDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
           G PG  G  GE G  GL G +GP+G+ G  G RG  G +G+ G  G+KG
Sbjct: 814 GFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKG 862



 Score =  189 bits (480), Expect = 5e-48
 Identities = 110/250 (44%), Positives = 140/250 (56%), Gaps = 27/250 (10%)

Query: 109 PGQKGE------PGETGQPGPKGEAGNLGIPGPPGVVGPQG------PRGYKGEKGLKGE 156
           PG KG+      PG  G+ G +G+ G  G+PGPPG  G +G      PRG  GE G +G 
Sbjct: 552 PGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGL 611

Query: 157 RGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAM-- 214
            G +G PG PG PG +G  GP+G KG++G  G  G  G +G T G  T+G  G QGA+  
Sbjct: 612 LGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQG-TPG--TQGLPGPQGAIGP 668

Query: 215 -------GSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGS 267
                  G PGL G PG+ G  G  G++G  G KG  G SG +G  G  G  G+KG  G 
Sbjct: 669 HGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGI 728

Query: 268 KGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGS 327
           +G  G +G+ G +G PG KGD G+KG++GE+G PG  G  GP+G    KG  GPTG  G 
Sbjct: 729 RGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGP---KGRTGPTGDPGP 785

Query: 328 RGFKGSKGEL 337
            G  G KG+L
Sbjct: 786 PGLMGEKGKL 795



 Score =  187 bits (475), Expect = 2e-47
 Identities = 106/252 (42%), Positives = 126/252 (50%), Gaps = 13/252 (5%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
            +PG  GE GETG  GP G  G  G  GP G  G  GP+G  G  G  G  G++G PG  G
Sbjct: 1160 LPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESG 1219

Query: 168  KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKG 227
             PG QGEPG KG +G  G  G  GQ G  G        G+ G +G  G  G  G PG  G
Sbjct: 1220 SPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG 1279

Query: 228  EKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKG 287
            E G  G+ G  GD+G  G+ G+ G  G  GE G  G  G +G +G  G  GR G  GAKG
Sbjct: 1280 EGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKG 1339

Query: 288  DPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSA 347
            DPG  G  G+ GP   +GP GP G  G  G+RG  G  G +G  G+ G+          A
Sbjct: 1340 DPGAIGAPGKTGP---VGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQ----------A 1386

Query: 348  GLSKPFPPPNIP 359
            G   P  PP +P
Sbjct: 1387 GPPGPVGPPGLP 1398



 Score =  187 bits (474), Expect = 2e-47
 Identities = 112/251 (44%), Positives = 134/251 (53%), Gaps = 24/251 (9%)

Query: 109 PGQKGEPGETGQPGPKGEAGN------LGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGV 162
           PG+ GE G+ G+ GP+G  G       LG  GPPG+ GP G RG  G +G KG  G QG 
Sbjct: 585 PGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGE 644

Query: 163 PGYPGK---PGAQGEPGP---------KGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGD 210
           PG PG+   PG QG PGP         KG +G  GL G+ G  G  G        G KG+
Sbjct: 645 PGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN 704

Query: 211 QGAMGSPGLHGGPGAKGEKGE---MGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGS 267
           QG  G  G  G PG +G KG     G KG  G+KG  G  G +G  G KG+ G  G  GS
Sbjct: 705 QGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGS 764

Query: 268 KGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGL---LGPTGPKGDIGNKGVRGPTGK 324
           +G+ G EG  GR G  G  G PG+ GEKG+LG PGL    G  GPKG +G  G  G +G+
Sbjct: 765 RGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGE 824

Query: 325 KGSRGFKGSKG 335
           KG+RG  G  G
Sbjct: 825 KGARGLSGKSG 835



 Score =  187 bits (474), Expect = 2e-47
 Identities = 111/262 (42%), Positives = 133/262 (50%), Gaps = 42/262 (16%)

Query: 110  GQKGEPGETGQPGPKGEAGN---LGIPGP---PGVVGPQGPRGYKGEKGLKGERGDQGVP 163
            G+ G+PGE G PGPKG  G+    G PGP   PG  GP G  G +G+ G KG+RG+ G P
Sbjct: 1240 GESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEP 1299

Query: 164  GYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSP------ 217
            G PG PG  GE GP G  G  G  G  G +G +G       KG KGD GA+G+P      
Sbjct: 1300 GQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGG------KGAKGDPGAIGAPGKTGPV 1353

Query: 218  ------------GLHGGPGAKGEKGEMGEKGEMGDKGCCGD------SGERGGKGQKGEG 259
                        GL G PG+ G++G  G  G+ G  G  G        G+ G KG+KG  
Sbjct: 1354 GPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHP 1413

Query: 260  GM------KGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDI 313
            G+       GE+G KGD G+ G  G  G  G  G PG  G  G  GPPGL GP GPKG  
Sbjct: 1414 GLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAK 1473

Query: 314  GNKGVRGPTGKKGSRGFKGSKG 335
            G  G  GP G+KG +G  G  G
Sbjct: 1474 GATGPGGPKGEKGVQGPPGHPG 1495



 Score =  186 bits (473), Expect = 3e-47
 Identities = 115/285 (40%), Positives = 130/285 (45%), Gaps = 32/285 (11%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGE------------ 156
           PG++G PG  G  GP G  G LG PGP GV G  G RG KG KG KGE            
Sbjct: 693 PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGV 752

Query: 157 RGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGS 216
           +GD+G  G PG  G  G  GPKG  G  G  G  G  G KG        G  G QG  GS
Sbjct: 753 KGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGS 812

Query: 217 PGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGK 276
            G  G PGA GEKG  G  G+ G +G  G +G RG +G +G  G  G KG+ G  G  G 
Sbjct: 813 LGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGP 872

Query: 277 SGRNGLPGAKGDPGIKGEKGELGPP------------------GLLGPTGPKGDIGNKGV 318
            G  GLPG +G  G  G KG  GPP                  G  GP GP G +G +G 
Sbjct: 873 PGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGA 932

Query: 319 RGPTGKKGSRGFKGSKGELAR--VPRSAFSAGLSKPFPPPNIPIK 361
            G TG  G RG  G  G      +P +A   G      PP  P K
Sbjct: 933 AGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGK 977



 Score =  186 bits (473), Expect = 3e-47
 Identities = 110/249 (44%), Positives = 129/249 (51%), Gaps = 16/249 (6%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQ------GPRGYKGEKGLKGERGDQGV 162
            PG+ G PG  GQ G  G  G  G PGPPGVVGPQ      GP G +G  G  G  G+QG+
Sbjct: 897  PGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGL 956

Query: 163  PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
            PG  GK G +G+PGP G  G  G  G++G  G +G        G  G  G  G+ G  G 
Sbjct: 957  PGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERG------LPGTAGGPGLKGNEGPSGP 1010

Query: 223  PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGL 282
            PG  G  GE G  G  G  G  G  G +G  G  GE G+ GEKG  G +G +G  G  GL
Sbjct: 1011 PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGL 1070

Query: 283  PGAKGDPGIKGE---KGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGEL-A 338
            PG  G PG+ GE   KGE+G PG  G  G KG+ G  G  GP G  G  G  G+ GE  A
Sbjct: 1071 PGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGA 1130

Query: 339  RVPRSAFSA 347
            R P+  F A
Sbjct: 1131 RGPQGHFGA 1139



 Score =  186 bits (472), Expect = 4e-47
 Identities = 103/251 (41%), Positives = 135/251 (53%), Gaps = 24/251 (9%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           G  G  G TG+PGP G+ G+ G+ G  G +GPQGPRG +G  G  G+ G +G  G  G  
Sbjct: 487 GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGAR 546

Query: 170 GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGN------CTKGEKGDQGAM--------- 214
           G  G+PG KGD+G  GL G+ G+KG +GDT            GE+GD G +         
Sbjct: 547 GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 606

Query: 215 ---------GSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEK 265
                    G PG+ G PG +G  G  G KG +G +G  G  G++G  G +G  G +G  
Sbjct: 607 GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAI 666

Query: 266 GSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKK 325
           G  G+ G +GK G  G+PG+ G PG  G++G  G  G  GP+GP+G +G  G RG  G  
Sbjct: 667 GPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVD 726

Query: 326 GSRGFKGSKGE 336
           G RG KG KGE
Sbjct: 727 GIRGLKGHKGE 737



 Score =  185 bits (470), Expect = 7e-47
 Identities = 109/270 (40%), Positives = 133/270 (49%), Gaps = 42/270 (15%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGP---RGYKGEKGL---------KGE 156
            PG  G PGE G PG  G+ G  G PGPPG  G  GP   RG+ GE+GL         KG 
Sbjct: 945  PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 1004

Query: 157  RGDQGVPGYPGKPGAQG------------EPGPKGDKGNIGLGGVKGQKGSKGDTCGNCT 204
             G  G PG  G PG +G             PGP+G  G  G  GV G+KG  G T  +  
Sbjct: 1005 EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGV 1064

Query: 205  KGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKG------------------CCGD 246
            +G  G  G  G PG+ G  G KGE G+ G+KG  G+KG                    G 
Sbjct: 1065 QGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGA 1124

Query: 247  SGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGP 306
             GE G +G +G  G KG++G++G +G  G  G  GLPG  G+ G  G+ G +GPPG  GP
Sbjct: 1125 DGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGP 1184

Query: 307  TGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
             GP G  G  G +GP G  G+ G  G KGE
Sbjct: 1185 RGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1214



 Score =  184 bits (468), Expect = 1e-46
 Identities = 107/250 (42%), Positives = 132/250 (52%), Gaps = 27/250 (10%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGY---KGEKGLKGERGDQGVPG 164
            VPG+KG  G TG+ G +G  G  G  GPPGV G  G +G     G+KG KG +G+ G PG
Sbjct: 1049 VPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPG 1108

Query: 165  YPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPG 224
             PG  G  G+PG  G  G  G  G +G  G+KGD      +G +G  G  G  GL G PG
Sbjct: 1109 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGD------EGTRGFNGPPGPIGLQGLPG 1162

Query: 225  AKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPG 284
              GEKGE G+ G MG  G  G  G  G  G  G  G  G  G+ G  G +G+ G +G PG
Sbjct: 1163 PSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPG 1222

Query: 285  AKGDPGIK------GEKGELGPPGLLGPTGPKGDIGNKGVR------------GPTGKKG 326
             +G+PG+K      GEKGE G PG  GP GPKG  G+ G +            GP G+ G
Sbjct: 1223 IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGG 1282

Query: 327  SRGFKGSKGE 336
             RG  G+KG+
Sbjct: 1283 PRGQDGAKGD 1292



 Score =  181 bits (459), Expect = 1e-45
 Identities = 106/264 (40%), Positives = 135/264 (51%), Gaps = 14/264 (5%)

Query: 110  GQKGEPGETGQPGPKG---EAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYP 166
            G KG  G TG PGP G   E G LG+PG PG  G QGP+G  G  G  G  G++G  G  
Sbjct: 772  GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLS 831

Query: 167  GKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAK 226
            GK G +GE GP G +G  G  G  G+ G+KG + G+   G  G++G  G  G +G PG K
Sbjct: 832  GKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK 891

Query: 227  GEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAK 286
            G  G  G+ G  G  G  G+ G +G  G  G  G+ G +G+ G++G  G+ G  G PG  
Sbjct: 892  GPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPP 951

Query: 287  GDPGI------KGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGEL--- 337
            G+ G+      +G KG+ GPPG  G  GP G  G  G RG  G  G  G KG++G     
Sbjct: 952  GEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPP 1011

Query: 338  --ARVPRSAFSAGLSKPFPPPNIP 359
              A  P    +AG   P  PP  P
Sbjct: 1012 GPAGSPGERGAAGSGGPIGPPGRP 1035



 Score =  180 bits (457), Expect = 2e-45
 Identities = 106/239 (44%), Positives = 123/239 (51%), Gaps = 15/239 (6%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
            G  G PG  G PG +G AG+ G  GPPG  GPQGP G  GEKG+ GE+G  G  G  G  
Sbjct: 1006 GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 1065

Query: 170  GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSP---GLHGGPGAK 226
            G  G PGP G  G   + G  G KG  GD     TKG KG+ G  G P   G  G PGA 
Sbjct: 1066 GPVGLPGPAGPPG---VAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAA 1122

Query: 227  GEKGEMGEKGEMGDKGCCGDSGERGGKGQKGE---GGMKGEKGSKGDSGMEGKSGRNGLP 283
            G  GE G +G  G  G  GD G RG  G  G     G+ G  G KG++G  G  G  G P
Sbjct: 1123 GADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPP 1182

Query: 284  GAKGDPGIKGEKGELGPPGLLGPTGP------KGDIGNKGVRGPTGKKGSRGFKGSKGE 336
            G +G  G  G  G  GPPG +G  GP       G+ G+ G++G  G KG RG +G KGE
Sbjct: 1183 GPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGE 1241



 Score =  176 bits (445), Expect = 5e-44
 Identities = 103/239 (43%), Positives = 117/239 (48%), Gaps = 15/239 (6%)

Query: 110  GQKGEPGETGQPGPKGE---AGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYP 166
            G  G PGE G PGP+G     G  G PGPPG  G  G  G +GE G +G+ G  G PG  
Sbjct: 868  GPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVV 927

Query: 167  GKPGAQGE---------PGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSP 217
            G  GA GE         PGP G  G  GL G  G++G+KGD       G+ G  G  G P
Sbjct: 928  GPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFP 987

Query: 218  GLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKS 277
            G  G PG  G  G  G +G  G  G  G  GERG     G GG  G  G  G  G  G +
Sbjct: 988  GERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGA---AGSGGPIGPPGRPGPQGPPGAA 1044

Query: 278  GRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
            G  G+PG KG  G  G  G  GP GL GP GP G  G  G +G  G  G +G KG+KGE
Sbjct: 1045 GEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE 1103



 Score =  172 bits (436), Expect = 6e-43
 Identities = 104/265 (39%), Positives = 124/265 (46%), Gaps = 16/265 (6%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPG---VVGPQGPRGYKGEKGLKGERGDQGVPGYP 166
            GQ+G  G TG+ G KG +G  G  GPPG   + GPQGP G+ G KG  G  G  G+PG+P
Sbjct: 847  GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHP 906

Query: 167  GK------------PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAM 214
            G+            PG  G  GP+G  G  G  G +G  G  G        G  G +G  
Sbjct: 907  GQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTK 966

Query: 215  GSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGME 274
            G PG  G PG  G  G  G  GE G  G  G  G +G +G  G  G  G  G +G +G  
Sbjct: 967  GDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSG 1026

Query: 275  GKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSK 334
            G  G  G PG +G PG  GEKG  G  G +GPTG  G  G  G+ GP G  G  G  G K
Sbjct: 1027 GPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDK 1086

Query: 335  GELARVPRSAFSAGLSKPFPPPNIP 359
            GE+   P    + G      PP  P
Sbjct: 1087 GEVGD-PGQKGTKGNKGEHGPPGPP 1110



 Score =  171 bits (433), Expect = 1e-42
 Identities = 104/256 (40%), Positives = 124/256 (48%), Gaps = 13/256 (5%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRG------YKGEKGLKGERGDQGVP 163
            G  G  GE G  GPKG  G  G PGPPG++G +G  G      Y G +G KG  G  G P
Sbjct: 760  GVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFP 819

Query: 164  GYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGP 223
            G  G+ GA+G  G  G +G  G  G +GQ+G +G T  +  KG  G  G  G PG  G P
Sbjct: 820  GASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLP 879

Query: 224  GAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLP 283
            G +G  G  G KG  G  G  G  G  G +G+ G  G  G  G  G  G +G +G  G  
Sbjct: 880  GPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPM 939

Query: 284  GAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRS 343
            G +G PG  G  GE G PG  G  G KGD G  G  G  G  G RGF G +G    +P +
Sbjct: 940  GERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERG----LPGT 995

Query: 344  AFSAGL---SKPFPPP 356
            A   GL     P  PP
Sbjct: 996  AGGPGLKGNEGPSGPP 1011



 Score =  166 bits (420), Expect = 4e-41
 Identities = 102/265 (38%), Positives = 129/265 (48%), Gaps = 37/265 (13%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQG-----PRGYKGEKGLKGE------- 156
           PG +G PG  G PG +G  G  G+PG  G  GP G     P  +    G KG        
Sbjct: 413 PGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEA 472

Query: 157 -------------RGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNC 203
                        RG  G  GY G+PG  G+PG  G KG  G  G +G +G +G T    
Sbjct: 473 QAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPG 532

Query: 204 TKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKG 263
             G +G  GA G+ G+ G PG KG++G  G  G  G+KG  GD+G +G  G  GE G +G
Sbjct: 533 KAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERG 592

Query: 264 EKGSKGDSGMEGKSGRNGLPGAKGDPGI------------KGEKGELGPPGLLGPTGPKG 311
           + G  G  G+ G+SG  GL G KG PGI            +G KG LGP G  GP G +G
Sbjct: 593 DDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQG 652

Query: 312 DIGNKGVRGPTGKKGSRGFKGSKGE 336
             G +G+ GP G  G  G KG +G+
Sbjct: 653 TPGTQGLPGPQGAIGPHGEKGPQGK 677



 Score =  155 bits (392), Expect = 8e-38
 Identities = 126/370 (34%), Positives = 157/370 (42%), Gaps = 74/370 (20%)

Query: 25  TTPHTKFTKKSEEREMPKGLKPSSGPPPEEEETLFT--------EMAEMAEPITKP--SA 74
           TTP  +     EE E+   L+ S  PP EEE+T           +  E  E  T P    
Sbjct: 287 TTPDYQDPTPGEEEEI---LESSLLPPLEEEQTDLQVPPTADRFQAEEYGEGGTDPPEGP 343

Query: 75  LDSVFGTATLSPFENFTLDPADFFLNCCDCCSPVPGQKGEPGETGQP----------GPK 124
            D  +G       E   L PA          +   G +G  GE G+P          GP 
Sbjct: 344 YDYTYGYGD-DYREETELGPA-LSAETAHSGAAAHGPRGLKGEKGEPAVLEPGMLVEGPP 401

Query: 125 GEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKPG-------------- 170
           G  G  G+ GPPG+ G  GP G  GE+G  G  G  G  G PG PG              
Sbjct: 402 GPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGG 461

Query: 171 ----------AQGEP----------GPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGD 210
                     AQ +           GP G  G  G  G  GQ GS G       KGE GD
Sbjct: 462 DKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPG------LKGESGD 515

Query: 211 QGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGD 270
            G  G  G  G  G  G+ G  G  G  G +G  GD G +G +G  G  G+ GEKG +GD
Sbjct: 516 LGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGD 575

Query: 271 SGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKG---VRGPTGKKGS 327
           +G +G      LPG  G+ G +G+ GE+GP GL G +GP+G +G KG   + GP G +G 
Sbjct: 576 TGAQG------LPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGM 629

Query: 328 RGFKGSKGEL 337
            G +G KG L
Sbjct: 630 DGPQGPKGSL 639



 Score =  142 bits (359), Expect = 5e-34
 Identities = 84/199 (42%), Positives = 99/199 (49%), Gaps = 21/199 (10%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
            G  G PG  G+ G KG  G+ G  G PG  GP GP G  G+ G  G RG  G  G  G+P
Sbjct: 1321 GPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRP 1380

Query: 170  GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
            GA G+ GP G  G  GL G++G  G+KG+      KG  G  G +G P            
Sbjct: 1381 GATGQAGPPGPVGPPGLPGLRGDAGAKGE------KGHPGLIGLIGPP------------ 1422

Query: 230  GEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDP 289
               GE+GE GD+G  G  G  G KG+ G  G  G  G  G  G+ G +G  G  GA G  
Sbjct: 1423 ---GEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPG 1479

Query: 290  GIKGEKGELGPPGLLGPTG 308
            G KGEKG  GPPG  GP G
Sbjct: 1480 GPKGEKGVQGPPGHPGPPG 1498



 Score =  108 bits (270), Expect = 1e-23
 Identities = 66/162 (40%), Positives = 79/162 (48%), Gaps = 18/162 (11%)

Query: 109  PGQKGEPGET---------GQPGP------KGEAGNLGIPGPPGVVGPQGPRGYKGEKGL 153
            PG  G PG+T         G+PGP       G  G  G PG  G  GP GP G  G  GL
Sbjct: 1341 PGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGL 1400

Query: 154  KGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGA 213
            +G+ G +G  G+PG  G  G PG +G+KG+ GL G +G  G KG+       G  G  G 
Sbjct: 1401 RGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEM---GIPGASGPIGP 1457

Query: 214  MGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQ 255
             G PGL G  G KG KG  G  G  G+KG  G  G  G  G+
Sbjct: 1458 GGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGE 1499



 Score = 97.8 bits (242), Expect = 2e-20
 Identities = 57/135 (42%), Positives = 70/135 (51%), Gaps = 15/135 (11%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGL------KGERGDQGVP 163
            GQ+G PG TGQ GP G  G  G+PG  G  G +G +G+ G  GL      +GE+GD+G+P
Sbjct: 1375 GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1434

Query: 164  GYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGP 223
            G  G PG +GE G  G  G IG GG  G  G  G          KG +GA G  G  G  
Sbjct: 1435 GPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGP---------KGAKGATGPGGPKGEK 1485

Query: 224  GAKGEKGEMGEKGEM 238
            G +G  G  G  GE+
Sbjct: 1486 GVQGPPGHPGPPGEV 1500



 Score = 76.3 bits (186), Expect = 6e-14
 Identities = 88/369 (23%), Positives = 137/369 (37%), Gaps = 56/369 (15%)

Query: 16  IAGMNTIAKTTPHTKFTKKSEEREMPKGLKPSSGPPPEEEETLFTEMAEMAEPITKPSAL 75
           + G+    ++    +   +  +RE P+  +P       +++       +  EP ++P+  
Sbjct: 211 VPGVQAAYESCEQKELECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQPT-- 268

Query: 76  DSVFGTATLSPFENFTLDPADFFLNCCDCCSPVPGQKGEPGETGQPGP-KGEAGNLGIP- 133
           +S++       ++  T           D   P PG++ E  E+    P + E  +L +P 
Sbjct: 269 ESLYYDYEPPYYDVMTTGTTP------DYQDPTPGEEEEILESSLLPPLEEEQTDLQVPP 322

Query: 134 ----------GPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKPGAQGEPGPKGDKGN 183
                     G  G   P+GP  Y    G   +  ++   G    P    E    G   +
Sbjct: 323 TADRFQAEEYGEGGTDPPEGPYDYT--YGYGDDYREETELG----PALSAETAHSGAAAH 376

Query: 184 IGLGGVKGQKGSKGDTC----GNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMG 239
               G +G KG KG+      G   +G  G +G  G   L G PG +G  G +G+ GE G
Sbjct: 377 ----GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAG---LIGPPGIQGNPGPVGDPGERG 429

Query: 240 DKGCCGDSGERGGKGQKGE-----------GGMKGEKGSKGDSGMEG--KSGRNGLPGAK 286
             G  G  G  G  G  G            GG KG   +  ++  +   +  R  L G  
Sbjct: 430 PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPP 489

Query: 287 GDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFS 346
           G  G  G  G LG PG  G  G  GD+G      P G +G +G  G  G+  R  R+   
Sbjct: 490 GPMGYTGRPGPLGQPGSPGLKGESGDLG------PQGPRGPQGLTGPPGKAGRRGRAGAD 543

Query: 347 AGLSKPFPP 355
                P  P
Sbjct: 544 GARGMPGDP 552



 Score = 75.9 bits (185), Expect = 8e-14
 Identities = 40/84 (47%), Positives = 51/84 (60%), Gaps = 15/84 (17%)

Query: 109  PGQKGEPGETGQPGPKG---EAGNLGIPG---------PPGVVGPQGPRGYKGEK---GL 153
            PG++GE G+ G PGP+G   + G +GIPG         PPG+ GP GP+G KG     G 
Sbjct: 1422 PGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGP 1481

Query: 154  KGERGDQGVPGYPGKPGAQGEPGP 177
            KGE+G QG PG+PG PG   +P P
Sbjct: 1482 KGEKGVQGPPGHPGPPGEVIQPLP 1505



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 32/85 (37%), Positives = 41/85 (48%), Gaps = 10/85 (11%)

Query: 285 AKGDPGIKGEKGELG--PPGLL--GPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARV 340
           A G  G+KGEKGE     PG+L  GP GP+G     G+ GP G +G+ G  G  GE    
Sbjct: 375 AHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGP---AGLIGPPGIQGNPGPVGDPGERGPP 431

Query: 341 PRSAFSAGLSKPFPPPN---IPIKF 362
            R+        P PP     +P +F
Sbjct: 432 GRAGLPGSDGAPGPPGTSLMLPFRF 456



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 28/80 (35%), Positives = 34/80 (42%), Gaps = 13/80 (16%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQG--------PRGYKGEKGLKGER-- 157
            +PG  G  G  G  GP G  G  G+ GPPG  GP G            K  + + G R  
Sbjct: 1463 LPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLM 1522

Query: 158  -GDQGVP--GYPGKPGAQGE 174
              D+ +P  G PG PG   E
Sbjct: 1523 QEDEAIPTGGAPGSPGGLEE 1542


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score =  195 bits (495), Expect = 9e-50
 Identities = 108/239 (45%), Positives = 129/239 (53%), Gaps = 12/239 (5%)

Query: 109 PGQKGEPGETGQPGPKG------EAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGV 162
           PGQ+G  G  G PGP+G      E G  G PG PG+ G  GP G+ G +G  GE+G QG 
Sbjct: 640 PGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGP 699

Query: 163 PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
           PG  G PG  G  G KG  GN GL G KG+KG  G        G KGDQG  G+PG  G 
Sbjct: 700 PGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGE 759

Query: 223 PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGS------KGDSGMEGK 276
            G +G KG+ G+ GE G  G  G+ G+ G  G  G  G  G KGS       G  G +GK
Sbjct: 760 DGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGK 819

Query: 277 SGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
           SG+ G PG +G+ G  G +GE G PG  G  GPKGD+G  G  G  G+KG  G +G  G
Sbjct: 820 SGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPG 878



 Score =  193 bits (491), Expect = 3e-49
 Identities = 105/227 (46%), Positives = 124/227 (54%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
           PG +G  GE G  GP G AG  G PGP GV G  G RG +GEKG KGE G  G  G  G 
Sbjct: 685 PGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGL 744

Query: 169 PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGE 228
            G QG+PG  G +G  G  G KGQ G  G+     + GEKG  G  G PG  G PG KG 
Sbjct: 745 KGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGS 804

Query: 229 KGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGD 288
            G  G  G +G+KG  G +G+ G +G++G  G +GE+G  G +G  G  G  G  GA G 
Sbjct: 805 IGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGI 864

Query: 289 PGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
           PG KG  G  GPPG  GP GP G  G  G  G  G++G  GF+G  G
Sbjct: 865 PGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTG 911



 Score =  190 bits (483), Expect = 2e-48
 Identities = 115/275 (41%), Positives = 131/275 (47%), Gaps = 25/275 (9%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG  G  G  G+ GP G AG +G+PG  G  GP GP G KG +G +G  G  G  G PG 
Sbjct: 1000 PGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGP 1059

Query: 169  ------PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
                  PGA G  G +GDKG++G  G KG KG KGD       G +G  G  G PG  G 
Sbjct: 1060 LGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGA 1119

Query: 223  PGAKGEKGEMGEKGEMGDKGCCG------------DSGERGGKGQKGEGGMKGEKGSKGD 270
             G +G  G  G+KG+ G +G  G              GE+G  G  G  G  G  G +G 
Sbjct: 1120 QGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGP 1179

Query: 271  SGMEGKSGRNGLPGAKGDPGIKGEKGELG------PPGLLGPTGPKGDIGNKGVRGPTGK 324
             G  G  G  GLPG  G PG  GEKGE G      PPG  G  GPKGDIG KG  GP+G 
Sbjct: 1180 QGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGA 1239

Query: 325  KGSRGFKGSKGELARVPRSAFSAGLSKPFPPPNIP 359
             G  G KG  GE      S    GL     PP  P
Sbjct: 1240 AGPPGKKGPPGE-DGAKGSVGPTGLPGDLGPPGDP 1273



 Score =  189 bits (479), Expect = 6e-48
 Identities = 102/240 (42%), Positives = 132/240 (55%), Gaps = 18/240 (7%)

Query: 108  VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
            +PG  G+PG  G+ G +G+AG+ G PG PG+ GP+G  G KG+ G  G  G  G  G PG
Sbjct: 1191 LPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPG 1250

Query: 168  KPGAQGEPGPKGDKGNIGLGG---VKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPG 224
            + GA+G  GP G  G++G  G   V G  GS G+      KG+ GD G  G PG  G PG
Sbjct: 1251 EDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGE------KGDPGDVGGPGPPGASGEPG 1304

Query: 225  AKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPG 284
            A G  G+ G  G MG +G  G+ G +G  G  G  G  G  G++G  G  G  G  G+PG
Sbjct: 1305 APGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPG 1364

Query: 285  AKGDPGIKGEKGELGPPGLLGP---------TGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
              G+PG+ G  G++GPPG LGP         TGPKG+ G+ G+ G  G  G  G KG +G
Sbjct: 1365 PVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQG 1424



 Score =  188 bits (477), Expect = 1e-47
 Identities = 106/263 (40%), Positives = 136/263 (51%), Gaps = 36/263 (13%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPG------------PPGVVGPQGPRGYKGEKGL---K 154
            G++G+PG TGQPGPKG+ G  G PG            PPG  GP+GP G++G+ G     
Sbjct: 839  GERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHP 898

Query: 155  GERGDQGVPGYPGKP------------------GAQGEPGPKGDKGNIGLGGVKGQKGSK 196
            G+RG+ G  G  G P                  G +G PGP G  G  GL G++G++G+K
Sbjct: 899  GQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAK 958

Query: 197  GDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQK 256
            G+       G++G  G  G PG  GGPG  G  G  G+KG  G  G  G  GERG  G  
Sbjct: 959  GELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPA 1018

Query: 257  GEGGMKGEKGSK---GDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDI 313
            G  G+ G+ GS+   G +G +G  G  G PG  G  GI G  G LGPPG  GP+G +GD 
Sbjct: 1019 GGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDK 1078

Query: 314  GNKGVRGPTGKKGSRGFKGSKGE 336
            G+ G  G  G KG +G  G  G+
Sbjct: 1079 GDVGAPGHKGSKGDKGDAGPPGQ 1101



 Score =  187 bits (476), Expect = 1e-47
 Identities = 111/286 (38%), Positives = 143/286 (50%), Gaps = 35/286 (12%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGP---RGYKGEKGLKGE------RGD 159
            PG  G PGE G PG +G  G  G  GPPG +G +GP   RG+ G KG  G+      +GD
Sbjct: 937  PGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGD 996

Query: 160  QGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGL 219
            +G PG  G  G+ GE GP G  G IGL G  G +G  G      ++GE+G  G  G  G+
Sbjct: 997  KGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGI 1056

Query: 220  HGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGR 279
             G  G  G  G  G  GE GDKG  G  G +G KG KG+ G  G+ G +G +G  G  G 
Sbjct: 1057 PGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGA 1116

Query: 280  NGLPGAKGDPGIKGEKGE---------LGPPGLL---GPTGPKGDIGN------------ 315
            +G  G +G PG+ G+KG+         +GPPGL    GP G KG++G+            
Sbjct: 1117 DGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGP 1176

Query: 316  KGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPP--PNIP 359
            +G +GPTG +G+ G  G  G+   V           P PP  P IP
Sbjct: 1177 RGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIP 1222



 Score =  187 bits (474), Expect = 2e-47
 Identities = 115/263 (43%), Positives = 136/263 (51%), Gaps = 23/263 (8%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQG---PRGYKGEKGLKGERGDQGVPGYP 166
           GQ+G+ G  GQPGP GE G  G  GPPG  G  G   PRG  G +G  G  G  GV G  
Sbjct: 563 GQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGID 622

Query: 167 GKPGAQG------EPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLH 220
           G PGA+G      EPGP G +GN G  G+ G +G  G      T GEKG  G  G PGL 
Sbjct: 623 GAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIG------TPGEKGPPGNPGIPGL- 675

Query: 221 GGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRN 280
             PG+ G  G  G +G  G+KG  G  G  G  G  G  G+KG  G++G  G +G+ G +
Sbjct: 676 --PGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGED 733

Query: 281 GLPGAKGDPGIKGEKGELGPPGLL---GPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGEL 337
           G PG KGD G+KG++G+ G PG     GP GPKG  G  G  GP G  G +G  G  G L
Sbjct: 734 GFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPG-L 792

Query: 338 ARVPRSAFSAGLSKPFPPPNIPI 360
              P      G S  FP P  PI
Sbjct: 793 PGYPGRPGPKG-SIGFPGPLGPI 814



 Score =  187 bits (474), Expect = 2e-47
 Identities = 107/241 (44%), Positives = 127/241 (52%), Gaps = 21/241 (8%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
            G KG+ G+ G PG  G  G  G PGPPG  G QG RG  G  G KG+ G +G  G  G P
Sbjct: 1088 GSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPP 1147

Query: 170  GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG---PGAK 226
            G QG PGP G+KG +G  G  G  G+ G       +G +G  G+ G+PGL GG   PGA 
Sbjct: 1148 GLQGLPGPPGEKGEVGDVGSMGPHGAPGP------RGPQGPTGSEGTPGLPGGVGQPGAV 1201

Query: 227  GEKGEMGEKGEMGDKGC------CGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRN 280
            GEKGE G+ G+ G  G        GD GE+G  G  G  G  G+KG  G+ G +G  G  
Sbjct: 1202 GEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPT 1261

Query: 281  GLPGAKGDP------GIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSK 334
            GLPG  G P      GI G  GE G PG +G  GP G  G  G  GP GK+G  G  G +
Sbjct: 1262 GLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGRE 1321

Query: 335  G 335
            G
Sbjct: 1322 G 1322



 Score =  186 bits (473), Expect = 3e-47
 Identities = 114/265 (43%), Positives = 137/265 (51%), Gaps = 39/265 (14%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
            G+ G PG  G PG  G  G++G PGP G +G +G  G  G+ GL+GERG  G  G  G+P
Sbjct: 785  GKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQP 844

Query: 170  GAQGEPGPKGDKGNIGLGGVKGQKGSKG-----------DTCGNCTK----------GEK 208
            GA G+PGPKGD G  G  G+ G+KG  G              G+  K          GE 
Sbjct: 845  GATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGEL 904

Query: 209  GDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSK 268
            G QG  G PG  G  G +G+ GE+G  GE G  G  G  GE+G  G +G  G KGE G  
Sbjct: 905  GFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPP 964

Query: 269  GDSGMEGKSGRNGLPGAKGDP------GIKGEKGELGP------PGLLGPTGPKGDI--- 313
            G  G EG +G  G PG KG P      G+KG+KG  GP      PG  GP GP G I   
Sbjct: 965  GPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLP 1024

Query: 314  ---GNKGVRGPTGKKGSRGFKGSKG 335
               G++G  GP GKKGSRG +G  G
Sbjct: 1025 GQSGSEGPVGPAGKKGSRGERGPPG 1049



 Score =  186 bits (471), Expect = 5e-47
 Identities = 106/254 (41%), Positives = 133/254 (52%), Gaps = 27/254 (10%)

Query: 109  PGQKGEPGETGQ------PGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGV 162
            PG+KGE G+ G       PGP+G  G  G  G PG+ G  G  G  GEKG +G+ GD G 
Sbjct: 1156 PGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGP 1215

Query: 163  PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPG---- 218
            PG PG PG +G+ G KGD G  G  G  G+KG  G+     + G  G  G +G PG    
Sbjct: 1216 PGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGV 1275

Query: 219  --LHGGPGAKGEKGEMG---EKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGM 273
              + G PG KG+ G++G     G  G+ G  G  G+RG  G  G  G +GEKG+KG+ G 
Sbjct: 1276 SGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGP 1335

Query: 274  EGKSGRNGLPGAKGDPGIKG------------EKGELGPPGLLGPTGPKGDIGNKGVRGP 321
            +G  GR G  GA+G PG  G            E G LG PG +GP GP G  G  G++G 
Sbjct: 1336 DGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGD 1395

Query: 322  TGKKGSRGFKGSKG 335
            TG KG +G  G  G
Sbjct: 1396 TGPKGEKGHIGLIG 1409



 Score =  185 bits (470), Expect = 7e-47
 Identities = 113/259 (43%), Positives = 134/259 (51%), Gaps = 19/259 (7%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
            G  G PG+ G PG  G  G++G  G PG +GP G  G  G  G  GE+GD G  G PG P
Sbjct: 1238 GAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPP 1297

Query: 170  GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
            GA GEPG  G  G  G  G  G++G +G+      KG KG+ G  G PG  G  GA+G  
Sbjct: 1298 GASGEPGAPGPPGKRGPSGHMGREGREGE------KGAKGEPGPDGPPGRTGPMGARGPP 1351

Query: 230  GEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGS---KGDSGMEGKSGRNGLPGAK 286
            G +G +G  G  G  G+ G  G  GQ G  G  G  G    KGD+G +G+ G  GL G  
Sbjct: 1352 GRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLI 1411

Query: 287  GDPGIKGEKGELGPPGLLGPTGPKGD------IGNKGVRGPTGKKGSRGFKGSKGELARV 340
            G PG  GEKG+ G PG+ GP GPKGD      IG+ G  GP G  G  G KGSKG     
Sbjct: 1412 GPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGS---- 1467

Query: 341  PRSAFSAGLSKPFPPPNIP 359
            P S    G + P  PP  P
Sbjct: 1468 PGSMGPRGDTGPAGPPGPP 1486



 Score =  185 bits (469), Expect = 9e-47
 Identities = 106/240 (44%), Positives = 128/240 (53%), Gaps = 12/240 (5%)

Query: 109 PGQKGEPGETG---QPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGY 165
           PG  G PG TG    PG KG  G  G PGPPG  G  G +G  G +GL G  G++G PG 
Sbjct: 610 PGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGN 669

Query: 166 PGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGA 225
           PG PG  G  GP G  G+ G  G KG +G  G        G +G +G  G+ GL G  G 
Sbjct: 670 PGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGE 729

Query: 226 KGE------KGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGR 279
           KGE      KG++G KG+ G  G  G  GE G +G KG+ G  GE+G  G +G +GK G 
Sbjct: 730 KGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGV 789

Query: 280 NGLPGAKGDPGIKGE---KGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
            GLPG  G PG KG     G LGP G  G +G  G  G +G RGP G +G RG  G+ G+
Sbjct: 790 PGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQ 849



 Score =  185 bits (469), Expect = 9e-47
 Identities = 112/280 (40%), Positives = 134/280 (47%), Gaps = 48/280 (17%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERG---------D 159
            PG +G+ G  G PG +GE G  G  GPPG  G  GP+G  GE G  GERG         +
Sbjct: 886  PGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGE 945

Query: 160  QGVPGYPGKPGAQGE------------------PGPKGDKGNIGLGGVKGQKGSKGDTCG 201
            QG+PG  G+ GA+GE                  PGPKG  G+ G  G+KG KG  G    
Sbjct: 946  QGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGA 1005

Query: 202  NCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDK-------------------- 241
            N + GE+G  G  G  GL G  G++G  G  G+KG  G++                    
Sbjct: 1006 NGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGP 1065

Query: 242  -GCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGP 300
             G  G SGE G KG  G  G KG KG KGD+G  G+ G  G  G  G PG  G +G  GP
Sbjct: 1066 PGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGP 1125

Query: 301  PGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARV 340
            PGL G  G  G  G  GV GP G +G  G  G KGE+  V
Sbjct: 1126 PGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDV 1165



 Score =  184 bits (468), Expect = 1e-46
 Identities = 113/265 (42%), Positives = 128/265 (48%), Gaps = 45/265 (16%)

Query: 110  GQKGEPGETGQPGPKGE---AGNLGIPGPPGVVGPQGPRGYKGE------KGLKGERGDQ 160
            G+KG  GE G PGP G+    G LG  GPPG  GP G  G KG+      KG KG++GD 
Sbjct: 1037 GKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDA 1096

Query: 161  GVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLH 220
            G PG PG  G  G PGP G  G  G  G  G  G KGD       G +G  G +G PGL 
Sbjct: 1097 GPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDD------GVRGFVGVIGPPGLQ 1150

Query: 221  GGPGAKGEKGEMGEKGEMG---------------------------DKGCCGDSGERGGK 253
            G PG  GEKGE+G+ G MG                             G  G+ GERG  
Sbjct: 1151 GLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDA 1210

Query: 254  GQKGEGGMKGEKGSKGDSGMEGKSGRNGL---PGAKGDPGIKGEKGELGPPGLLGPTGPK 310
            G  G  G  G  G KGD G +G SG +G    PG KG PG  G KG +GP GL G  GP 
Sbjct: 1211 GDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPP 1270

Query: 311  GDIGNKGVRGPTGKKGSRGFKGSKG 335
            GD G  G+ G  G+KG  G  G  G
Sbjct: 1271 GDPGVSGIDGSPGEKGDPGDVGGPG 1295



 Score =  184 bits (466), Expect = 2e-46
 Identities = 113/257 (43%), Positives = 134/257 (52%), Gaps = 16/257 (6%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG+KG PGE G  G  G  G  G  GPPG  G  G  G  GEKG  G+ G  G PG  G+
Sbjct: 1243 PGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGE 1302

Query: 169  PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSP------GLHGG 222
            PGA G PG +G  G++G  G +G+KG+KG+   +   G  G  GA G P      GL G 
Sbjct: 1303 PGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGI 1362

Query: 223  PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGL 282
            PG  GE G +G  G+MG  G  G SG     G KG+ G KGEKG  G  G+ G  G  G 
Sbjct: 1363 PGPVGEPGLLGAPGQMGPPGPLGPSGL---PGLKGDTGPKGEKGHIGLIGLIGPPGEAGE 1419

Query: 283  PGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPR 342
             G +G PG++G  G  G PG  GP G  G  G  GV GP G+KGS+G  GS G     PR
Sbjct: 1420 KGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMG-----PR 1474

Query: 343  SAFSAGLSKPFPPPNIP 359
                 G + P  PP  P
Sbjct: 1475 G--DTGPAGPPGPPGAP 1489



 Score =  183 bits (464), Expect = 3e-46
 Identities = 109/254 (42%), Positives = 128/254 (50%), Gaps = 27/254 (10%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKG------ERGDQGV 162
           PG  GE GE G  GP G  G  G PGP G++GP+G  G  G  G+ G       +G+ G 
Sbjct: 574 PGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGP 633

Query: 163 PGYPGKPGAQGE---------------PGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGE 207
           PG PG PG QG                PG KG  GN G+ G+ G  G  G        GE
Sbjct: 634 PGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGE 693

Query: 208 KGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQ---KGEGGMKGE 264
           KG QG  GS G  G PG +G KG  G +G  G+KG  G+ G  G KG    KG+ G  G 
Sbjct: 694 KGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGA 753

Query: 265 KGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGL---LGPTGPKGDIGNKGVRGP 321
            G +G+ G EG  G+ G  G +G PG  GEKG+LG PGL    G  GPKG IG  G  GP
Sbjct: 754 PGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGP 813

Query: 322 TGKKGSRGFKGSKG 335
            G+KG  G  G  G
Sbjct: 814 IGEKGKSGKTGQPG 827



 Score =  181 bits (460), Expect = 1e-45
 Identities = 105/235 (44%), Positives = 121/235 (51%), Gaps = 12/235 (5%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           GQ G+ GE G PG  GE G LG+PG PG  G  GP+G  G  G  G  G++G  G  G+P
Sbjct: 767 GQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQP 826

Query: 170 GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
           G +GE GP G +G  G  G  GQ G KGD   +   G  G  G  G PGL G PG  G K
Sbjct: 827 GLEGERGPPGSRGERGQPGATGQPGPKGDVGQD---GAPGIPGEKGLPGLQGPPGFPGPK 883

Query: 230 GEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDP 289
           G  G +G+ G  G  G  GE G +GQ G  G  G  G +G +G  G  G  G PG  G P
Sbjct: 884 GPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPP 943

Query: 290 ---------GIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
                    G +G KGELGPPG LG  GP G  G  G +G  G  G  G KG KG
Sbjct: 944 GEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKG 998



 Score =  181 bits (458), Expect = 2e-45
 Identities = 101/229 (44%), Positives = 126/229 (55%), Gaps = 6/229 (2%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           G  G  G TG+PGP G  G+ G+ G  G  GPQGPRG +G  G  G  G  G PG  G  
Sbjct: 479 GPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGAR 538

Query: 170 GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
           G  G+ GPKGD+G  GL G+ G+KG +GD  G+   G+ G  G  G  G  G PG  G+ 
Sbjct: 539 GLPGDTGPKGDRGFDGLPGLPGEKGQRGD-FGHV--GQPGPPGEDGERGAEGPPGPTGQA 595

Query: 230 GEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGD---SGMEGKSGRNGLPGAK 286
           GE G +G +G +G  G +G  G  G  G  G KG  G  G+    G +G  G  GLPG +
Sbjct: 596 GEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQ 655

Query: 287 GDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
           G  G  GEKG  G PG+ G  G  G +G+ G  GPTG+KG++G  GS G
Sbjct: 656 GLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAG 704



 Score =  179 bits (453), Expect = 6e-45
 Identities = 97/228 (42%), Positives = 122/228 (53%), Gaps = 9/228 (3%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG  G  G  G PG  G+ G+ G+ G  GV+GP G +G  G  G KGE GD G  G  G 
Sbjct: 1114 PGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGA 1173

Query: 169  PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGE 228
            PG +G  GP G +G  GL G  GQ G+          GEKG++G  G PG  G PG  G 
Sbjct: 1174 PGPRGPQGPTGSEGTPGLPGGVGQPGA---------VGEKGERGDAGDPGPPGAPGIPGP 1224

Query: 229  KGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGD 288
            KG++GEKG+ G  G  G  G++G  G+ G  G  G  G  GD G  G  G +G+ G+ G+
Sbjct: 1225 KGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGE 1284

Query: 289  PGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
             G  G+ G  GPPG  G  G  G  G +G  G  G++G  G KG+KGE
Sbjct: 1285 KGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGE 1332



 Score =  178 bits (452), Expect = 8e-45
 Identities = 101/235 (42%), Positives = 125/235 (53%), Gaps = 18/235 (7%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPG----- 164
           G+KGE GE G PG KG+ G  G  G PG  GP+G  G +G KG  G+ G++G PG     
Sbjct: 725 GEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEK 784

Query: 165 ----YPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLH 220
                PG PG  G PGPKG  G  G  G  G+KG  G T      G+ G +G  G PG  
Sbjct: 785 GKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKT------GQPGLEGERGPPGSR 838

Query: 221 GGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRN 280
           G  G  G  G+ G KG++G  G  G  GE+G  G +G  G  G KG  G    +GK GR 
Sbjct: 839 GERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGH---QGKDGRP 895

Query: 281 GLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
           G PG +G+ G +G+ G  GP G+LGP G  G++G  G RGP G  G  G +G  G
Sbjct: 896 GHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPG 950



 Score =  177 bits (449), Expect = 2e-44
 Identities = 103/248 (41%), Positives = 128/248 (51%), Gaps = 18/248 (7%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVV------GPQGPRGYKGEKGLKGERGDQG 161
           +PG  G  GE G  GP+G  G  G  GPPG V      G  G RG  G+ G KG+RG  G
Sbjct: 495 LPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDG 554

Query: 162 VPGYPGKPGAQ------GEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMG 215
           +PG PG+ G +      G+PGP G+ G  G  G  G  G  G+       G +G  G  G
Sbjct: 555 LPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTG 614

Query: 216 SPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEG 275
            PG+ G  GA G KG +G  GE G  G  G+ G +G  G +G  G  GEKG  G+ G+ G
Sbjct: 615 RPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPG 674

Query: 276 KSGRNGLPGAKGDPGIKGEK------GELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRG 329
             G +G  G  G  G  GEK      G  GPPG  GP G KG  GN+G++G  G+KG  G
Sbjct: 675 LPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDG 734

Query: 330 FKGSKGEL 337
           F G KG++
Sbjct: 735 FPGFKGDV 742



 Score =  177 bits (448), Expect = 2e-44
 Identities = 111/270 (41%), Positives = 129/270 (47%), Gaps = 29/270 (10%)

Query: 110  GQKGEPGETGQPGPKGEAGNLGIPGPPGV------VGPQGPRGYKGEKGLKGERGDQGVP 163
            GQKG+ G  G  G  G  G  G+PGPPG       VG  GP G  G +G +G  G +G P
Sbjct: 1130 GQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTP 1189

Query: 164  GYP---GKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLH 220
            G P   G+PGA GE G +GD G+ G  G  G  G KGD       GEKGD G  G+    
Sbjct: 1190 GLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDI------GEKGDSGPSGAA--- 1240

Query: 221  GGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRN 280
            G PG KG  GE G KG +G  G  GD G  G  G  G  G  GEKG  GD G  G  G +
Sbjct: 1241 GPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGAS 1300

Query: 281  GLPGAKGDPGIK---------GEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFK 331
            G PGA G PG +         G +GE G  G  GP GP G  G  G RGP G+ G  G +
Sbjct: 1301 GEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLR 1360

Query: 332  GSKGELARVPRSAFSAGLSKPFP--PPNIP 359
            G  G +           +  P P  P  +P
Sbjct: 1361 GIPGPVGEPGLLGAPGQMGPPGPLGPSGLP 1390



 Score =  174 bits (441), Expect = 2e-43
 Identities = 98/243 (40%), Positives = 125/243 (51%), Gaps = 9/243 (3%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG+KG+PG+ G PGP G +G  G PGPPG    +GP G+ G +G +GE+G +G PG  G 
Sbjct: 1282 PGEKGDPGDVGGPGPPGASGEPGAPGPPG---KRGPSGHMGREGREGEKGAKGEPGPDGP 1338

Query: 169  PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGE 228
            PG  G  G +G  G +G  G++G  G  G+       G+ G  G +G  GL   PG KG+
Sbjct: 1339 PGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGL---PGLKGD 1395

Query: 229  KGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGD 288
             G  GEKG +G  G  G  GE G KG +G  G++G  G KGD G  G  G  G PG  G 
Sbjct: 1396 TGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGV 1455

Query: 289  PGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAG 348
             G  G+KG  G PG +   GP+GD G  G  GP G          +     VP      G
Sbjct: 1456 AGPLGQKGSKGSPGSM---GPRGDTGPAGPPGPPGAPAELHGLRRRRRFVPVPLPVVEGG 1512

Query: 349  LSK 351
            L +
Sbjct: 1513 LEE 1515



 Score =  170 bits (430), Expect = 3e-42
 Identities = 98/240 (40%), Positives = 119/240 (49%), Gaps = 12/240 (5%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
           PG  G  G  G  GPKG+ G  G+PG PG  G +G  G+ G+ G  GE G++G  G PG 
Sbjct: 532 PGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGP 591

Query: 169 PGAQGEPGPKG---------DKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGL 219
            G  GEPGP+G           G  G+ G+ G  G+KG+       G  G QG  GS GL
Sbjct: 592 TGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGL 651

Query: 220 HGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGR 279
            G  G  G  GE G  G  G  G  G  G  G  G +G  G KG +G  G +G  G  G 
Sbjct: 652 PGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGP 711

Query: 280 NGLPGAKGDPGIKGEKGELGP---PGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
            G+ G  G+ G++GEKGE G    PG  G  G KGD G  G  GP G+ G  G KG  G+
Sbjct: 712 RGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQ 771



 Score =  169 bits (427), Expect = 7e-42
 Identities = 102/259 (39%), Positives = 124/259 (47%), Gaps = 19/259 (7%)

Query: 108  VPGQKGEPGE------TGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQG 161
            +PG  G PG+       G PG KG+ G++G PGPPG  G  G  G  G++G  G  G + 
Sbjct: 1263 LPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGRE- 1321

Query: 162  VPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHG 221
              G  G+ GA+GEPGP G  G  G  G +G  G  G       +G +G  G +G PGL G
Sbjct: 1322 --GREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVG------PEGLRGIPGPVGEPGLLG 1373

Query: 222  GPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNG 281
             PG  G  G +G  G  G KG  G  GE+G  G  G  G  GE G KGD G+ G  G  G
Sbjct: 1374 APGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPG 1433

Query: 282  LPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVP 341
              G  G PG  G  G  GPPG+ GP G KG  G+ G  GP G  G  G  G  G     P
Sbjct: 1434 PKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPG----AP 1489

Query: 342  RSAFSAGLSKPFPPPNIPI 360
                     + F P  +P+
Sbjct: 1490 AELHGLRRRRRFVPVPLPV 1508



 Score =  168 bits (425), Expect = 1e-41
 Identities = 98/267 (36%), Positives = 123/267 (46%), Gaps = 39/267 (14%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGP----------------------- 144
           V G  G PG  G PG  G  G  G+PG PG+ G +GP                       
Sbjct: 402 VVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSF 461

Query: 145 ----------------RGYKGEKGLKGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGG 188
                           +G  G  GL G  G  G+PG+PG  G +G  GP+G +G  G  G
Sbjct: 462 QQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHG 521

Query: 189 VKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSG 248
             G+ G  G    +  +G  GD G  G  G  G PG  GEKG+ G+ G +G  G  G+ G
Sbjct: 522 PPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDG 581

Query: 249 ERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTG 308
           ERG +G  G  G  GE G +G  G  G  G  G PG  G  G  G KG +GPPG  GP G
Sbjct: 582 ERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPG 641

Query: 309 PKGDIGNKGVRGPTGKKGSRGFKGSKG 335
            +G+ G++G+ GP G  G+ G KG  G
Sbjct: 642 QQGNHGSQGLPGPQGLIGTPGEKGPPG 668



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 50/118 (42%), Positives = 61/118 (51%), Gaps = 15/118 (12%)

Query: 106  SPVPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGY 165
            S +PG KG+   TG  G KG  G +G+ GPPG  G +G +G  G +G  G +GD   PG 
Sbjct: 1387 SGLPGLKGD---TGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGD---PGP 1440

Query: 166  PGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGP 223
            PG  G+ G PGP G  G +G  G KG  GS          G +GD G  G PG  G P
Sbjct: 1441 PGPIGSLGHPGPPGVAGPLGQKGSKGSPGS---------MGPRGDTGPAGPPGPPGAP 1489



 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 54/163 (33%), Positives = 69/163 (42%), Gaps = 15/163 (9%)

Query: 191 GQKGSKGDTC----GNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGD 246
           G+KG+KG+      G   +G  G  G  G  G  G PG  G  G+ G  G  G  G  G 
Sbjct: 373 GEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGI 432

Query: 247 SGERGGKG-------QKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELG 299
            G RG  G       Q   G  KG   S   +  +    +  L   KG PG  G  G  G
Sbjct: 433 DGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQL-SMKGPPGPVGLTGRPG 491

Query: 300 PPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPR 342
           P GL G  G KG+   +G  GP G +G +G  G  G + ++ R
Sbjct: 492 PVGLPGHPGLKGE---EGAEGPQGPRGLQGPHGPPGRVGKMGR 531



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 33/88 (37%), Positives = 41/88 (46%), Gaps = 7/88 (7%)

Query: 263 GEKGSKGDSGMEGKSGR-NGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGV--- 318
           GEKG+KG+  +  K  +  G PGA G  G+ G  G  GPPG  G  GP G  G  G+   
Sbjct: 373 GEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGI 432

Query: 319 ---RGPTGKKGSRGFKGSKGELARVPRS 343
              RGP G      F+ + G     P S
Sbjct: 433 DGIRGPPGTVIMMPFQFAGGSFKGPPVS 460


>gi|38570075 collagen, type XXV, alpha 1 isoform 1 [Homo sapiens]
          Length = 654

 Score =  194 bits (494), Expect = 1e-49
 Identities = 122/282 (43%), Positives = 140/282 (49%), Gaps = 61/282 (21%)

Query: 106 SPVPGQKGEPGETGQPGPKGEAGNLGIPGPPGV------VGPQGPRGYKGEKGLKGERGD 159
           S   G KGEPGE+G+PG KGE G  G+PG PG+      +GPQG  G  G  G KGERG+
Sbjct: 307 SSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGE 366

Query: 160 QGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPG- 218
            G PG     G +GEPG  G KG  G  G +G KGSKGD      +GEKGD GA G  G 
Sbjct: 367 AGPPGR----GERGEPGAPGPKGKQGESGTRGPKGSKGD------RGEKGDSGAQGPRGP 416

Query: 219 ------------------LH------------GGPGAKGEKGEMGEKGEMGDKGCCGDSG 248
                             LH            G PG  G +G  G KGE G  G  G  G
Sbjct: 417 PGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDG 476

Query: 249 ERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGEL---------- 298
           E+G KG KG+ G  G  G KG  G+ G  G NG+ G KGD G+ G +G            
Sbjct: 477 EQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPGP 536

Query: 299 -GPPGLLGP---TGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
            GPPG +GP    GPKG  G  G  GP G KG RG KG+ GE
Sbjct: 537 HGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGE 578



 Score =  193 bits (491), Expect = 3e-49
 Identities = 119/271 (43%), Positives = 132/271 (48%), Gaps = 42/271 (15%)

Query: 109 PGQKGEPGETGQPGP------------------------KGEAGNLGIPGPPGVVGPQGP 144
           PG KG+ GE G  GP                        KG+ G  G PGPPG  GP+GP
Sbjct: 149 PGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGP 208

Query: 145 RGYKGEKGLKGERGDQGVPGYPGKPGAQ---GEPGPKGDKGNIGLGGVKGQKGSKGDTCG 201
               G+ G  G RG  GVPG PGKPG Q   G  GP G KG+IG  G+ G  G KG+   
Sbjct: 209 ---PGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGL 265

Query: 202 NCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCC-----GDSGERGGKGQK 256
               G+ G  G  G PG  G  G  GE G  G+ GE GD G       G+ GE G  GQK
Sbjct: 266 PGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQK 325

Query: 257 GEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGL-----LGPTGPKG 311
           GE G+ G  G  G  G  G  G  G PG  G PG KGE+GE GPPG       G  GPKG
Sbjct: 326 GEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGPKG 385

Query: 312 DIGNKGVRGPTGKKGSRGFKGSKGELARVPR 342
             G  G RGP G KG RG KG  G  A+ PR
Sbjct: 386 KQGESGTRGPKGSKGDRGEKGDSG--AQGPR 414



 Score =  176 bits (447), Expect = 3e-44
 Identities = 107/276 (38%), Positives = 129/276 (46%), Gaps = 49/276 (17%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQG------ 161
           +PG KGE GE G PG +GE G  G PGP G  G  G RG KG KG +GE+GD G      
Sbjct: 357 LPGTKGERGEAGPPG-RGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRG 415

Query: 162 -------------------------------VPGYPGKPGAQGEPGPKGDKGNIGLGGVK 190
                                          V G PG PG QG  GPKG++G+ G+ G+ 
Sbjct: 416 PPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMD 475

Query: 191 GQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDK--------- 241
           G++G KG        G  G++G +G PGL G  G KGEKG+ G  G  G           
Sbjct: 476 GEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPG 535

Query: 242 --GCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELG 299
             G  G  G  G  G KG  G  G  G  G  G  G+ G  G PG +G  G+ G+ GE G
Sbjct: 536 PHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPG 595

Query: 300 PPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
             G  GP G KGD+G KG +G  G KG +G  G  G
Sbjct: 596 LDGFPGPRGEKGDLGEKGEKGFRGVKGEKGEPGQPG 631



 Score =  176 bits (446), Expect = 4e-44
 Identities = 117/301 (38%), Positives = 143/301 (47%), Gaps = 50/301 (16%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
           +PG  GEPG+       GE G +G  GPPG  G  G  G  G  G KGE G  G  G  G
Sbjct: 220 MPGVPGEPGK------PGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNG 273

Query: 168 KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCT--KGEKGDQGAMGS------PGL 219
            PG +GEPG +G+KG+ G  G KG  G KGD   +    KGE G+ G  G       PGL
Sbjct: 274 IPGPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGL 333

Query: 220 HGGPGAKGEKGEMGEKGEMGDKGCCGDSGERG-----GKGQKGEGGMKGEKGSKGDSGME 274
            G PG KGE G +G +GE G  G  G  GERG     G+G++GE G  G KG +G+SG  
Sbjct: 334 PGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGPKGKQGESGTR 393

Query: 275 GKSGRNGLPGAKGD---------PGIKGEKGE----------------------LGPPGL 303
           G  G  G  G KGD         PG KG++G                        GPPG 
Sbjct: 394 GPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGP 453

Query: 304 LGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPPPNIPIKFE 363
            GP G +G  G +G  G  G  G +G KGSKG++     +    G+  P  P    +K E
Sbjct: 454 PGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGE 513

Query: 364 K 364
           K
Sbjct: 514 K 514



 Score =  167 bits (422), Expect = 3e-41
 Identities = 104/263 (39%), Positives = 123/263 (46%), Gaps = 48/263 (18%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKG---------------- 152
           PG KG+ GE+G  GPKG  G+ G  G  G  GP+GP G KG++G                
Sbjct: 381 PGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQ 440

Query: 153 ------------------LKGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKG 194
                             L+G +G+QG PG PG  G QG  G KGD G+ G+ G KG  G
Sbjct: 441 RITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIG 500

Query: 195 SKGDTCGNCTKGEKGDQGAMGSPGLH-----GGPGAKGEKGEMGEKGEMGDKGCCGDSGE 249
             G    N  KGEKGD G  G  G       G PG  G  G MG  G  G KG  G  G 
Sbjct: 501 LPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGP 560

Query: 250 RGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGP 309
            G  G KGE G KG  G  G  G  G  G++G PG  G PG +GEKG+L         G 
Sbjct: 561 HGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDL---------GE 611

Query: 310 KGDIGNKGVRGPTGKKGSRGFKG 332
           KG+ G +GV+G  G+ G  G  G
Sbjct: 612 KGEKGFRGVKGEKGEPGQPGLDG 634



 Score =  149 bits (376), Expect = 5e-36
 Identities = 93/247 (37%), Positives = 118/247 (47%), Gaps = 40/247 (16%)

Query: 141 PQGPRGYKGEKGLKGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGG------------ 188
           P GP G +G++G +GE G       PG+PG QG PGPKGDKG  G  G            
Sbjct: 121 PAGPPGKRGKRGRRGESGP------PGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGF 174

Query: 189 ------------VKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKG 236
                       +KG +G  G        G  G  G  G PG  G  G +G  G  GE G
Sbjct: 175 LSADQQLIKRRLIKGDQGQAG------PPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPG 228

Query: 237 EMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKG 296
           + G++G  G  G  G KG  G  G+ G  G KG+ G+ G  G+NG+PG KG+PG +GEKG
Sbjct: 229 KPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKG 288

Query: 297 ELGPPGLLGPTGPKGDIGNK--GVRGPTGKKGSRGFKGSKG--ELARVPRSAFSAGLSKP 352
           + G  G  G TG KGD G+   G++G  G+ G  G KG  G   L  +P      G   P
Sbjct: 289 DAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGP 348

Query: 353 FPPPNIP 359
              P +P
Sbjct: 349 QGEPGLP 355



 Score =  136 bits (342), Expect = 5e-32
 Identities = 84/204 (41%), Positives = 107/204 (52%), Gaps = 31/204 (15%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
           V G  G PG  G  GPKGE G+ GIPG  G  G +G +G  G+ G+ GE+G  G+PG PG
Sbjct: 447 VTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPG 506

Query: 168 KPGAQGE--------------------PGPKGDKGNIGLGGVKGQKGSKGDTCGNCT--- 204
             G +GE                    PGP G  G +G  G+ G KG+ G    +     
Sbjct: 507 ANGMKGEKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGP 566

Query: 205 KGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGE 264
           KGE+G++GAMG PG  G  G  G+ GE G  G  G +G  GD GE   KG+KG  G+KGE
Sbjct: 567 KGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGE---KGEKGFRGVKGE 623

Query: 265 KGSKGDSGMEG-----KSGRNGLP 283
           KG  G  G++G     + G +GLP
Sbjct: 624 KGEPGQPGLDGLDAPCQLGPDGLP 647



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 32/91 (35%), Positives = 41/91 (45%), Gaps = 5/91 (5%)

Query: 274 EGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTG-----KKGSR 328
           E  S  N   G  G  G +G +GE GPPG  GP GP G  G+KG +G  G      K + 
Sbjct: 113 EAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINH 172

Query: 329 GFKGSKGELARVPRSAFSAGLSKPFPPPNIP 359
           GF  +  +L +        G + P  PP  P
Sbjct: 173 GFLSADQQLIKRRLIKGDQGQAGPPGPPGPP 203


>gi|11386161 alpha 2 type IX collagen [Homo sapiens]
          Length = 689

 Score =  194 bits (493), Expect = 1e-49
 Identities = 103/226 (45%), Positives = 123/226 (54%), Gaps = 6/226 (2%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           G  G PGE G  GP G AG  G  G PG+ GPQG  G KG  G  G  G  G PG PG  
Sbjct: 259 GATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMK 318

Query: 170 GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
           G+ G+ G  G  G+ GL GV GQ G+KG        G++G+ G  G PG  G PG +GE 
Sbjct: 319 GSAGQAGQPGSPGHQGLAGVPGQPGTKGG------PGDQGEPGPQGLPGFSGPPGKEGEP 372

Query: 230 GEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDP 289
           G  GE G  G  G  GD GERG  GQ G  G +G KG +G  G+ G  G  G+ G KG P
Sbjct: 373 GPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSP 432

Query: 290 GIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
           G  G +G++G PG+ G  G KG+ G  G  GP G++G RG  G  G
Sbjct: 433 GKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPG 478



 Score =  186 bits (471), Expect = 5e-47
 Identities = 102/234 (43%), Positives = 129/234 (55%), Gaps = 9/234 (3%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
           PG KG PG  G  G  G+ G LG PG  G  GP+G  G  GE+G+ G  G QG+ GYPG 
Sbjct: 180 PGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGM 239

Query: 169 PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGE 228
            G +GE GP G KG +G  G  G  G +G        GEKGD+G+ G  G  G  G KG 
Sbjct: 240 AGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGA 299

Query: 229 ------KGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGL 282
                  G+ G  G  G KG  G +G+ G  G +G  G+ G+ G+KG  G +G+ G  GL
Sbjct: 300 TGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGL 359

Query: 283 PGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
           PG  G P   G++GE GP G +GP G  G  G++G RGP G+ G +G +G KGE
Sbjct: 360 PGFSGPP---GKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGE 410



 Score =  185 bits (470), Expect = 7e-47
 Identities = 101/224 (45%), Positives = 124/224 (55%), Gaps = 12/224 (5%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPG---VVGPQGPRGYKGEKGLKGERGDQGVPGY 165
           PG  G+ G  G PG KG AG  G PG PG   + G  G  G KG  G +GE G QG+PG+
Sbjct: 303 PGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGF 362

Query: 166 PGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGA 225
            G PG +GEPGP+G+ G  G+ G KG +G +G        G+ G QG  G  G  G PG 
Sbjct: 363 SGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPV------GQPGPQGRQGPKGEQGPPGI 416

Query: 226 KGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGA 285
            G +G  G K   GDKG  G +G RG  G  G  G+ GEKG KG+SG  G  G+ G+ G 
Sbjct: 417 PGPQGLPGVK---GDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGE 473

Query: 286 KGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRG 329
            G PG  G+ G  G  G  GP GP+G  GN+GV G  G++G  G
Sbjct: 474 PGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEG 517



 Score =  182 bits (461), Expect = 8e-46
 Identities = 110/276 (39%), Positives = 139/276 (50%), Gaps = 51/276 (18%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
           PG KG PG+ G+PGP+G  G     GPPG  G  GPRG  G +G+ G++GDQG  G  G+
Sbjct: 342 PGTKGGPGDQGEPGPQGLPG---FSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQ 398

Query: 169 PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGE 228
           PG QG  GPKG++G  G+ G +G  G KGD     + G+ G +G +G PG+ G PG KGE
Sbjct: 399 PGPQGRQGPKGEQGPPGIPGPQGLPGVKGD---KGSPGKTGPRGKVGDPGVAGLPGEKGE 455

Query: 229 KGEMGEKGEMGDKGCCGD------SGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGL 282
           KGE GE G  G +G  G+      SG+ G  G +G  G  G +G  G+ G+ G+ GR G+
Sbjct: 456 KGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGV 515

Query: 283 PG------------------------------AKGDPGIKGEKGELGPPGLLGPTGPKGD 312
            G                              A G  G+ G  G  GPPG  G  GP G 
Sbjct: 516 EGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGH 575

Query: 313 IGNKGVRG---------PTGKKGSRGFKGSKGELAR 339
            G +GV G          TG KG RG KG  GE+ R
Sbjct: 576 PGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGR 611



 Score =  180 bits (457), Expect = 2e-45
 Identities = 105/239 (43%), Positives = 129/239 (53%), Gaps = 15/239 (6%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           G  G+PG  G+PGPKG+ G  G  G PG  GPQG RGY G  G KGE G  G  G  G  
Sbjct: 199 GILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAI 258

Query: 170 GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLH------GGP 223
           GA G PG +G +G  G  G KG +GS G       +G  G +GA G PG++      G P
Sbjct: 259 GATGPPGEEGPRGPPGRAGEKGDEGSPGI---RGPQGITGPKGATGPPGINGKDGTPGTP 315

Query: 224 GAKGEKGEMGEKGEMGDKGCC---GDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRN 280
           G KG  G+ G+ G  G +G     G  G +GG G +GE G +G  G  G  G EG+ G  
Sbjct: 316 GMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPR 375

Query: 281 GLPGAKGDPGIKGEKGELGP---PGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
           G  G +G  G KG++GE GP   PG  G  GPKG+ G  G+ GP G  G +G KGS G+
Sbjct: 376 GEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGK 434



 Score =  177 bits (448), Expect = 2e-44
 Identities = 103/256 (40%), Positives = 127/256 (49%), Gaps = 36/256 (14%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
           PG +GEPG  G PG  G  G  G PGP G +GPQG  G KG+   +GERG  G PG  G+
Sbjct: 348 PGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGD---QGERGPVGQPGPQGR 404

Query: 169 PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGE 228
            G +GE GP G  G  GL GVKG KGS G T         G +G +G PG+ G PG KGE
Sbjct: 405 QGPKGEQGPPGIPGPQGLPGVKGDKGSPGKT---------GPRGKVGDPGVAGLPGEKGE 455

Query: 229 KGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGD 288
           KGE GE G  G +G  G+ G  G  G  G  G++G  G  G  G+ G  G  G PG +G 
Sbjct: 456 KGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGV 515

Query: 289 PG------------------------IKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGK 324
            G                        +  ++  LG  G++GP GP G  G  G +GP G 
Sbjct: 516 EGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGH 575

Query: 325 KGSRGFKGSKGELARV 340
            G RG  G  G + ++
Sbjct: 576 PGPRGVPGIVGAVGQI 591



 Score =  175 bits (443), Expect = 9e-44
 Identities = 103/251 (41%), Positives = 123/251 (49%), Gaps = 24/251 (9%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGP---PGVVGPQGPRGYKGEKGLKGERGDQGVPG 164
           + G  G PG+ G PGPKGE G  G  GP   PG+ G  G +G  G  G+ G +G  G+PG
Sbjct: 49  IDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPG 108

Query: 165 YPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG-- 222
            PG PG  G  GP G  G +GL G  G +G KGD   +   G  G  G  G PG   G  
Sbjct: 109 PPGLPG-PGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLE 167

Query: 223 ------------PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGD 270
                       PG KG  G  G KG  G +G  GD G +G  G KG+ G  GE+G  G 
Sbjct: 168 GSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGP 227

Query: 271 SGMEGKSGRNGLPGAKGDPGIKGEKGEL------GPPGLLGPTGPKGDIGNKGVRGPTGK 324
            G +G  G  G+ G KG+ G  G KG +      GPPG  GP GP G  G KG  G  G 
Sbjct: 228 PGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGI 287

Query: 325 KGSRGFKGSKG 335
           +G +G  G KG
Sbjct: 288 RGPQGITGPKG 298



 Score =  173 bits (439), Expect = 3e-43
 Identities = 111/283 (39%), Positives = 135/283 (47%), Gaps = 31/283 (10%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPG-----------------PPGVVGP---QGPRGY 147
           + G KG+PG  G  GP G  G  G PG                 PPG+ GP   QG +G+
Sbjct: 135 IRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGH 194

Query: 148 KGEKGLKGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGE 207
            G++G+ G+ G QG PG  G  GA GE G  G  G  G+ G  G  G KG+T  +  KG 
Sbjct: 195 AGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGM 254

Query: 208 KGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGG------KGQKGEGGM 261
            G  GA G PG  G  G  G  GE G++G  G +G  G +G +G        G+ G  G 
Sbjct: 255 VGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGT 314

Query: 262 KGEKGSKGDSGMEGKSGRNGLPGAKGDPGIK---GEKGELGPPGLLGPTGPKGDIGNKGV 318
            G KGS G +G  G  G  GL G  G PG K   G++GE GP GL G +GP G  G  G 
Sbjct: 315 PGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGP 374

Query: 319 RGPTGKKGSRGFKGSKGELARV--PRSAFSAGLSKPFPPPNIP 359
           RG  G +G  G KG +GE   V  P      G      PP IP
Sbjct: 375 RGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIP 417



 Score =  138 bits (347), Expect = 1e-32
 Identities = 91/248 (36%), Positives = 115/248 (46%), Gaps = 51/248 (20%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
           +PG KG+ G  G+ GP+G+ G+ G+ G PG    +G +G  GE G KG++G +G PGYPG
Sbjct: 422 LPGVKGDKGSPGKTGPRGKVGDPGVAGLPG---EKGEKGESGEPGPKGQQGVRGEPGYPG 478

Query: 168 K------PGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTK---------------- 205
                  PG QG PGP G +G  G  GV GQ G +G    + T                 
Sbjct: 479 PSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLA 538

Query: 206 --------------------GEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCG 245
                               G  G  G  G  G HG PG +G  G +G  G++G+    G
Sbjct: 539 EVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGN---TG 595

Query: 246 DSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNG--LPGAKGDPGIKGEKGELGPPGL 303
             G+RG KG  GE G +G  G  G  G+ G  GR G  + G  GD G  G  GE G PGL
Sbjct: 596 PKGKRGEKGDPGEVG-RGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGL 654

Query: 304 LGPTGPKG 311
            GP G  G
Sbjct: 655 PGPVGLPG 662



 Score = 88.6 bits (218), Expect = 1e-17
 Identities = 68/195 (34%), Positives = 79/195 (40%), Gaps = 46/195 (23%)

Query: 167 GKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAK 226
           G PG +G PGP G  G      V G  G  GD                G PG  G PG K
Sbjct: 27  GPPGERGPPGPPGPPG------VPGSDGIDGDN---------------GPPGKAGPPGPK 65

Query: 227 GEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKG--------DSGMEGKSG 278
              GE G+ G  G  G  G  G  G KG+ G  G+ G KG  G          G  G  G
Sbjct: 66  ---GEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPG 122

Query: 279 RNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKG-VRG-------------PTGK 324
             G  G  G+ GI+G KG+ GP G  GP GP G  G  G ++G             P G 
Sbjct: 123 PPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGM 182

Query: 325 KGSRGFKGSKGELAR 339
           KG  G +G KG   +
Sbjct: 183 KGPPGLQGVKGHAGK 197



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 27/66 (40%), Positives = 32/66 (48%), Gaps = 15/66 (22%)

Query: 286 KGDPGIKGEKGELGPPGL---------------LGPTGPKGDIGNKGVRGPTGKKGSRGF 330
           +G PG +G  G  GPPG+                GP GPKG+ G  G  GP GK G  G 
Sbjct: 26  RGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGL 85

Query: 331 KGSKGE 336
            G+KGE
Sbjct: 86  TGAKGE 91


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score =  194 bits (492), Expect = 2e-49
 Identities = 115/284 (40%), Positives = 143/284 (50%), Gaps = 29/284 (10%)

Query: 92  LDPADFFL---NCCDCCSPVP-------------GQKGEPGETGQPGPKGEAGNLGIPGP 135
           L P D  L   + C+ C P P             G  G+PG  G  G KGEAG  G+PGP
Sbjct: 548 LSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGP 607

Query: 136 PGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGS 195
           PG+ GPQG +G +G  G  G++GDQG   +PG PG  G PG  G  G  G+ G  G  G 
Sbjct: 608 PGIAGPQGSQGERGADGEVGQKGDQG---HPGVPGFMGPPGNPGPPGADGIAGAAGPPGI 664

Query: 196 KGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQ 255
           +G      + G++G  G  G  GL G PG +G++G  G+ G  G+ G  G+ G  G +G 
Sbjct: 665 QG------SPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGA 718

Query: 256 KGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGN 315
           +G  G KG  G  G  G  G+SG  GLPG +G PG  G+ G  GP G  GP GP G  G+
Sbjct: 719 RGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGS 778

Query: 316 KGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPPPNIP 359
            G  G  G  G+ G KGSKGE      S    G   P  PP  P
Sbjct: 779 PGSPGEPGPSGTPGQKGSKGENG----SPGLPGFLGPRGPPGEP 818



 Score =  187 bits (475), Expect = 2e-47
 Identities = 107/246 (43%), Positives = 129/246 (52%), Gaps = 21/246 (8%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVG------PQGPRGYKGEKGLKGERGDQGV 162
           PG +G PG+ G PGP+G +G  GIPG  G  G      P G  G  GE GL G  G +G 
Sbjct: 662 PGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGP 721

Query: 163 PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
           PG+ G  G  G PGP+G+ G +GL G +G  G  GDT      G +G QG  G PG +G 
Sbjct: 722 PGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPT---GPQGPQGPRGPPGKNGS 778

Query: 223 PGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGL 282
           PG+ GE G  G  G+ G KG  G  G  G  G +G  G  GEKG  G  G+ GK G  G 
Sbjct: 779 PGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGF 838

Query: 283 PGAKGDPGIKGE------KGELGPPGL------LGPTGPKGDIGNKGVRGPTGKKGSRGF 330
            G +GDPGIKG+      KG+ G PG+       G  GP+G  G  G  GP G  G  GF
Sbjct: 839 KGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGF 898

Query: 331 KGSKGE 336
            G +GE
Sbjct: 899 PGLRGE 904



 Score =  187 bits (474), Expect = 2e-47
 Identities = 106/255 (41%), Positives = 132/255 (51%), Gaps = 6/255 (2%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
           VPG  G PG  G PG  G AG  G PG  G  G +GP G +G  GL G  G++G  G  G
Sbjct: 637 VPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDG 696

Query: 168 KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKG 227
           KPG  GEPG  G+ G  G  G +G  G KG T  +   G +G+ GAMG PG  G PG  G
Sbjct: 697 KPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDG 756

Query: 228 EKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKG 287
           + G  G +G  G +G  G +G  G  G+ G  G  G+KGSKG++G  G  G  G  G  G
Sbjct: 757 DTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPG 816

Query: 288 DPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSA 347
           +PG KG  G+ G PG  G  G KG+ G+ G++G  G  G +G  G  G    +P      
Sbjct: 817 EPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPG----IPGHKGHT 872

Query: 348 GLSKP--FPPPNIPI 360
           GL  P   P  N P+
Sbjct: 873 GLMGPQGLPGENGPV 887



 Score =  183 bits (464), Expect = 3e-46
 Identities = 107/268 (39%), Positives = 146/268 (54%), Gaps = 23/268 (8%)

Query: 108 VPGQKGEPGETGQPGPKGE---AGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGV-- 162
           +PG++G+ G  G+PGP GE   AG  G+PGP G  GP G +G+ G+ G  G RG+ G   
Sbjct: 685 IPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMG 744

Query: 163 ----PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPG 218
                G PGK G  G  GP+G +G  G  G  G  GS G+   + T G+KG +G  GSPG
Sbjct: 745 LPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPG 804

Query: 219 LHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSG 278
           L G  G +G  GE GEKG  G +G  G  GE G KG++G+ G+KG+KG  G    +G+ G
Sbjct: 805 LPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGG---KGQPG 861

Query: 279 RNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRG--PTGKKGSRGFKGSKGE 336
             G+PG KG  G+ G +G  G  G +GP GP G  G  G+RG  P+ +   R  +   G+
Sbjct: 862 DPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGK 921

Query: 337 ---------LARVPRSAFSAGLSKPFPP 355
                    LA++P +   +   +P PP
Sbjct: 922 QLETRLAYLLAQMPPAYMKSSQGRPGPP 949



 Score =  178 bits (452), Expect = 8e-45
 Identities = 113/287 (39%), Positives = 135/287 (47%), Gaps = 49/287 (17%)

Query: 110 GQKGEPGETGQPGP---KGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGE---RGDQGVP 163
           G+KG  GE G PGP   +G+ G  G+PGPPG  G  G  G +G  GL G    +GD+G P
Sbjct: 434 GEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGK-GKDGEPGLRGSPGLPGPLGTKGDRGAP 492

Query: 164 GYPGKPGAQGEP-----------GPKGDKGNIGLGGVKGQKGSKG--------------- 197
           G PG PG++G+P           GP GDKG+ G  G+ G  G +G               
Sbjct: 493 GIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGD 552

Query: 198 ------DTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERG 251
                 D C +C  G  G  G  G  G  G PG  G +G  G+KGE G  G  G  G  G
Sbjct: 553 INLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAG 612

Query: 252 GKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLL------G 305
            +G +GE G  GE G KGD G  G  G  G PG  G PG  G  G  GPPG+       G
Sbjct: 613 PQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEG 672

Query: 306 PTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKP 352
           P GP+G  G  G+ G  GK+G  G  G  GE    P  A   GL  P
Sbjct: 673 PPGPQGPSGLPGIPGEEGKEGRDGKPGPPGE----PGKAGEPGLPGP 715



 Score =  178 bits (451), Expect = 1e-44
 Identities = 105/262 (40%), Positives = 130/262 (49%), Gaps = 33/262 (12%)

Query: 95  ADFFLNCCDCCSPVPGQK---GEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEK 151
           AD   +C       PG K   GEPGE G+ G         +PG PG+ G  G +G  G  
Sbjct: 229 ADARASCILAAKTAPGLKQLNGEPGERGEDG---------LPGKPGLRGEIGEQGLAGRP 279

Query: 152 GLKGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGD------------- 198
           G   E+G+ G+PG PG PG +GE G +G+KG +GL G+KG +G KG+             
Sbjct: 280 G---EKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTT 336

Query: 199 ---TCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQ 255
              T      GE+G +G  G PGL G PG +G  GE+G +G  G  G  G  G  G  G 
Sbjct: 337 SLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGA 396

Query: 256 KGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGN 315
            G  G  G  G+ G SG  G  G  GL G  G  G +GEKG  G  G  GP GP+GD G 
Sbjct: 397 AGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGA 456

Query: 316 KGVRGP--TGKKGSRGFKGSKG 335
            G+ GP   GK G  G +GS G
Sbjct: 457 PGLPGPPGKGKDGEPGLRGSPG 478



 Score =  177 bits (450), Expect = 1e-44
 Identities = 99/254 (38%), Positives = 123/254 (48%), Gaps = 24/254 (9%)

Query: 107 PVPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQG----------------------- 143
           P  G  G PG +G PG KG  G+ G+PG PG  GP G                       
Sbjct: 504 PGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCND 563

Query: 144 -PRGYKGEKGLKGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGN 202
            P G  G  GL G +GD+GVPG PG+ G +G+ G  G  G  G  G+ G +GS+G+   +
Sbjct: 564 CPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGAD 623

Query: 203 CTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMK 262
              G+KGDQG  G PG  G PG  G  G  G  G  G  G  G  G+ G  G +G  G+ 
Sbjct: 624 GEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLP 683

Query: 263 GEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPT 322
           G  G +G  G +GK G  G PG  G+PG+ G +G  GPPG  G TG  G  G +G  G  
Sbjct: 684 GIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAM 743

Query: 323 GKKGSRGFKGSKGE 336
           G  G  G  G  G+
Sbjct: 744 GLPGQEGLPGKDGD 757



 Score =  175 bits (444), Expect = 7e-44
 Identities = 115/309 (37%), Positives = 146/309 (47%), Gaps = 63/309 (20%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGV------- 162
           G+ GE G  G+PG KGEAG  G PG PGV G +G +G KGE GL G +GD+G        
Sbjct: 268 GEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPA 327

Query: 163 ------------------------------PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQ 192
                                         PG PG+PG QG PG  G +G  G  G KGQ
Sbjct: 328 GPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQ 387

Query: 193 KGSKG--DTCGNC-------TKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGC 243
           +G+ G     GN          G  G  G++G+PGL G PG  GE+GE G  GE G  G 
Sbjct: 388 EGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGP 447

Query: 244 CGDSGERG--------GKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGA---KGDPGIK 292
            G  G+ G        GKG+ GE G++G  G  G  G +G  G  G+PG+   +GDPGI 
Sbjct: 448 VGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGI- 506

Query: 293 GEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKP 352
              G  GPPG  GP G KG  G++G+ G  G +G  G  G    L+    +  +  +   
Sbjct: 507 ---GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCND 563

Query: 353 FP--PPNIP 359
            P  PP +P
Sbjct: 564 CPPGPPGLP 572



 Score =  166 bits (421), Expect = 3e-41
 Identities = 106/288 (36%), Positives = 128/288 (44%), Gaps = 59/288 (20%)

Query: 107 PVPGQKGEPGETGQP------GPKGEAGNLGIPGPPGV-----VGPQGPRGYKGEKGLKG 155
           P  G+ GEPG  G P      G KG+ G  GIPG PG      +G  GP G  G  G KG
Sbjct: 463 PGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKG 522

Query: 156 ERGDQGVPGYPGKPGAQGEPG---------------------PKGDKGNIGLGGVKGQKG 194
             G +G+PG+PG  G  G  G                     P G  G  GL G KG KG
Sbjct: 523 SPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKG 582

Query: 195 SKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDK------------- 241
             G      T+G+KG+ G  G PG  G  G +G +GE G  GE+G K             
Sbjct: 583 VPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMG 642

Query: 242 --------------GCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKG 287
                         G  G  G +G  G++G  G +G  G  G  G EGK GR+G PG  G
Sbjct: 643 PPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPG 702

Query: 288 DPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
           +PG  GE G  GP G  GP G KG  G+ G  GP G+ G+ G  G +G
Sbjct: 703 EPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEG 750



 Score =  166 bits (421), Expect = 3e-41
 Identities = 108/307 (35%), Positives = 137/307 (44%), Gaps = 73/307 (23%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPG------------PPGVVGPQGPRGYKGEKGLKGE 156
            PG KG  G++G PGP+GE+G +G+PG            P G  GPQGPR      G  G+
Sbjct: 722  PGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPR------GPPGK 775

Query: 157  RGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGS 216
             G  G PG PG  G  G+ G KG+ G+ GL G  G +G  G+       GEKG  G  G 
Sbjct: 776  NGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGE------PGEKGVPGKEGV 829

Query: 217  PGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGK 276
            PG  G PG KGE+G+ G KG+ G  G  G  G+ G  G KG  G+ G +G  G++G  G 
Sbjct: 830  PGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGP 889

Query: 277  SGRNGLPG--------------------------------------------AKGDPGIK 292
             G  G PG                                            ++G PG  
Sbjct: 890  PGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPP 949

Query: 293  GEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKP 352
            G  G+ G PG  GP G  G  G  G+ GP+G  G +G +G+KG+       A   GL   
Sbjct: 950  GPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGD-----PGAPGVGLRGE 1004

Query: 353  FPPPNIP 359
              PP IP
Sbjct: 1005 MGPPGIP 1011



 Score =  160 bits (404), Expect = 3e-39
 Identities = 104/276 (37%), Positives = 124/276 (44%), Gaps = 62/276 (22%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
            PG  GEPG +G PG KG  G  G PG PG +GP+GP G  GEKG+ G+ G  G PG PG 
Sbjct: 779  PGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGF 838

Query: 169  PGAQGEPGPKGDKG------NIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
             G +G+PG KGDKG        G  G+ G KG  G        GE G  G  G PG  G 
Sbjct: 839  KGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGF 898

Query: 223  PGAKGE--------------------------------------KGEMGEKGEMGDKGCC 244
            PG +GE                                      +G  G  G  G  G  
Sbjct: 899  PGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLP 958

Query: 245  GDSGERGGKGQKGEGGM---------KGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEK 295
            G +G  G  G+ G+GG+         KGE+G+KGD G  G     GL G  G PGI G+ 
Sbjct: 959  GRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGV----GLRGEMGPPGIPGQP 1014

Query: 296  GELGP-----PGLLGPTGPKGDIGNKGVRGPTGKKG 326
            GE G      PG+ GP G  G  G+ G+ GP G  G
Sbjct: 1015 GEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPG 1050



 Score =  150 bits (378), Expect = 3e-36
 Identities = 90/204 (44%), Positives = 109/204 (53%), Gaps = 22/204 (10%)

Query: 149 GEKGLKGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEK 208
           G K L GE G++G  G PGKPG +GE G   ++G  G  G KG+ G  G       +GEK
Sbjct: 244 GLKQLNGEPGERGEDGLPGKPGLRGEIG---EQGLAGRPGEKGEAGLPGAPGFPGVRGEK 300

Query: 209 GDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDS----------GERGGKGQKGE 258
           GDQG  G  GL   PG KG++GE GE G  G  G  G +          GE+G KG+KG+
Sbjct: 301 GDQGEKGELGL---PGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGD 357

Query: 259 GGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLG------PTGPKGD 312
            G+ GE G +G  G  G  G  G PGAKG  G  G  G  G PG  G      P+GP G 
Sbjct: 358 PGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGS 417

Query: 313 IGNKGVRGPTGKKGSRGFKGSKGE 336
           +G  G+RG  GK G RG KG+ GE
Sbjct: 418 VGAPGLRGTPGKDGERGEKGAAGE 441



 Score =  150 bits (378), Expect = 3e-36
 Identities = 103/266 (38%), Positives = 122/266 (45%), Gaps = 45/266 (16%)

Query: 106  SPVPGQKGEPGETGQPGPKGEAGNLGIPGPP---GVVGPQGPRGYKGEKGLKGERGDQGV 162
            S  PGQKG  GE G PG  G  G  G PG P   GV G +G  G  GE G KGERGD G+
Sbjct: 788  SGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGI 847

Query: 163  PGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGG 222
             G  G PG +G+PG  G  G+ G  G+ G +G           GE G  G  G PG  G 
Sbjct: 848  KGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQG---------LPGENGPVGPPGPPGQPGF 898

Query: 223  PGAKGE-----------KGEMGEKGE---------------MGDKGCCGDSGERGGKGQK 256
            PG +GE           + E+G++ E                  +G  G  G  G  G  
Sbjct: 899  PGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLP 958

Query: 257  GEGGMKGEKGSKGDSGMEGKS---GRNGLPGAKGDPGIKGE--KGELGPPGLLGPTGPKG 311
            G  G  GE G  G  G+EG S   G  G  GAKGDPG  G   +GE+GPPG+ G  G  G
Sbjct: 959  GRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPG 1018

Query: 312  --DIGNKGVRGPTGKKGSRGFKGSKG 335
                G  G+ GP G+ G  G  G  G
Sbjct: 1019 YAKDGLPGIPGPQGETGPAGHPGLPG 1044



 Score =  119 bits (299), Expect = 5e-27
 Identities = 96/304 (31%), Positives = 123/304 (40%), Gaps = 44/304 (14%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQG--PRGYKGEKGLKGERGDQGVPGYPG 167
           G + +P E    G +G  G       P  V PQ   P+G   E                 
Sbjct: 172 GPRTDPWENVDQGAQGACGRGNTSVLPSSVAPQCSMPKGTGHEFS--------------- 216

Query: 168 KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKG 227
              A G  GP   + +     +   K + G    N   GE+G+ G  G PGL G  G +G
Sbjct: 217 --AALGTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQG 274

Query: 228 EKGEMGEKGEMGDKGCCGDSGERGGK---GQKGEGGMKGEKGSKGDSGMEGKSGRNGLPG 284
             G  GEKGE G  G  G  G RG K   G+KGE G+ G KG +G+ G  G +G  GLPG
Sbjct: 275 LAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPG 334

Query: 285 A-------------------KGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKK 325
                               KGDPG+ GE G  G PG LGP GP G  G KG  G  G  
Sbjct: 335 TTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAP 394

Query: 326 GSRGFKGSKGELARVPRSAFSAGLSKP---FPPPNIPIKFEKILYNDQGNYSPVTGKFNC 382
           G+ G  G+ G +     S     +  P     P     + EK    ++G+  PV  + + 
Sbjct: 395 GAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDP 454

Query: 383 SIPG 386
             PG
Sbjct: 455 GAPG 458



 Score = 90.1 bits (222), Expect = 4e-18
 Identities = 67/202 (33%), Positives = 80/202 (39%), Gaps = 63/202 (31%)

Query: 109  PGQKGEPGETGQPGPKGEAGNLG---IPGPPGVVGPQGPRGYKGEKGLKGE--------- 156
            PG KG+PG+ G PG KG  G +G   +PG  G VGP GP G  G  GL+GE         
Sbjct: 854  PGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRR 913

Query: 157  -----------------------------RGDQGVPGYPGKPGAQGEPGPKGDKGNIGLG 187
                                         +G  G PG PGK G  G  GP G+ G  G G
Sbjct: 914  LIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQG 973

Query: 188  GV---------KGQKGSKGD--TCGNCTKGEKGDQGAMGSPG-----------LHGGPGA 225
            G+         KG++G+KGD    G   +GE G  G  G PG           + G  G 
Sbjct: 974  GLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGE 1033

Query: 226  KGEKGEMGEKGEMGDKGCCGDS 247
             G  G  G  G  G  G C  S
Sbjct: 1034 TGPAGHPGLPGPPGPPGQCDPS 1055



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 22/41 (53%), Positives = 24/41 (58%), Gaps = 5/41 (12%)

Query: 108  VPGQKGEPGET-----GQPGPKGEAGNLGIPGPPGVVGPQG 143
            +PGQ GEPG       G PGP+GE G  G PG PG  GP G
Sbjct: 1010 IPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPG 1050


>gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]
          Length = 1028

 Score =  194 bits (492), Expect = 2e-49
 Identities = 115/273 (42%), Positives = 135/273 (49%), Gaps = 46/273 (16%)

Query: 101 CCDC-CSPV---PGQKGEPG---ETGQPGPKGEAGNLGIPGPPGVVGP------------ 141
           CC   C P    PG +G+PG   E G+PG  GE G  G PG PG +GP            
Sbjct: 247 CCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGS 306

Query: 142 ------QGPRGYKGEKG---------LKGERGDQGVPGYPGKPG---AQGEPGPKGDKGN 183
                 +GP+GYKGEKG         +KGE G  G+PG  G PG    QG PGPKGD G 
Sbjct: 307 RGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGA 366

Query: 184 IGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGC 243
            GL G KG+ G+ G+       G  G  G  G  G  G PG  GEKGE G++G  G  G 
Sbjct: 367 FGLKGEKGEPGADGEA------GRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA 420

Query: 244 CGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGL 303
               GERGG G++G  G  G +G +GD G  G  G  G  G  G PG  GE G +GP G 
Sbjct: 421 ---PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGY 477

Query: 304 LGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
            G  GP G  G +G  GP G  G  G  G +GE
Sbjct: 478 RGDEGPPGSEGARGAPGPAGPPGDPGLMGERGE 510



 Score =  168 bits (425), Expect = 1e-41
 Identities = 107/261 (40%), Positives = 126/261 (48%), Gaps = 33/261 (12%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPG--- 164
           V G KGE G  G PG KG  G  GI GPPG  G  G  G KGEKG  G  G+ G PG   
Sbjct: 330 VDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSG 389

Query: 165 ------YPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKG---------EKG 209
                  PG+PG  GE G  GD+GN G  G  G++G  G+     T G         E G
Sbjct: 390 PSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAG 449

Query: 210 DQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKG---EGGMKGEKG 266
            QG  G  G  G PG  GE G +G KG  GD+G  G  G RG  G  G   + G+ GE+G
Sbjct: 450 PQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERG 509

Query: 267 SKGDSG-----------MEGKSGRNGLPGAKGDPGIKGEKGELGPPG-LLGPTGPKGDIG 314
             G +G             G  G  G+ G KG PG+KG++GE G PG       P+G  G
Sbjct: 510 EDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKG 569

Query: 315 NKGVRGPTGKKGSRGFKGSKG 335
            KG RGP G +G  G +G  G
Sbjct: 570 AKGYRGPEGPQGPPGHQGPPG 590



 Score =  159 bits (401), Expect = 7e-39
 Identities = 102/252 (40%), Positives = 123/252 (48%), Gaps = 32/252 (12%)

Query: 134 GPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQK 193
           GPPG+ G  G  G +G+ GL GE+G+ G PG PG  G  G  G KG+KG+ G  G +G K
Sbjct: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316

Query: 194 GSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGK 253
           G KG+      KG++G  G  G  G  G PG  G KG  G  G  G  G  GD G  G K
Sbjct: 317 GYKGE------KGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLK 370

Query: 254 GQKGEGGMKGE---KGSKGDSGMEGKSGRNGLPGAKGD------------PGIKGEKGEL 298
           G+KGE G  GE    GS G SG EG+ G  G PG KG+            PG +G  GE 
Sbjct: 371 GEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGER 430

Query: 299 GPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARV-----------PRSAFSA 347
           GP G  G  GP+GD G  G +G  G++G  G  G  GE   +           P S  + 
Sbjct: 431 GPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGAR 490

Query: 348 GLSKPFPPPNIP 359
           G   P  PP  P
Sbjct: 491 GAPGPAGPPGDP 502



 Score =  157 bits (398), Expect = 2e-38
 Identities = 91/206 (44%), Positives = 109/206 (52%), Gaps = 12/206 (5%)

Query: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169
           G +G+PGE G PG KGEAG+ G PGP G  G +G  G +G +G  G RG +G PG  G  
Sbjct: 392 GDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQ 451

Query: 170 GAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEK 229
           G QG  GP G  G+ G  G  G KG +GD      +G  G +GA G+PG  G PG  G  
Sbjct: 452 GDQGREGPVGVPGDPGEAGPIGPKGYRGD------EGPPGSEGARGAPGPAGPPGDPGLM 505

Query: 230 GEMGEKGEMGD--KGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLP---- 283
           GE GE G  G+  +G  G  G  G +G  G  G KG  G KGD G  G  G +       
Sbjct: 506 GERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPR 565

Query: 284 GAKGDPGIKGEKGELGPPGLLGPTGP 309
           G KG  G +G +G  GPPG  GP GP
Sbjct: 566 GVKGAKGYRGPEGPQGPPGHQGPPGP 591



 Score =  113 bits (283), Expect = 3e-25
 Identities = 74/174 (42%), Positives = 92/174 (52%), Gaps = 18/174 (10%)

Query: 211 QGAMGSPGLHGGPGAKGEKGEMG---EKGEMGDKGCCGDSGE---RGGKGQKGEGGMKGE 264
           Q A G PGL G PG +GE+G+ G   EKGE GD G  GD G    +G KG+KG  G KG 
Sbjct: 253 QPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGS 312

Query: 265 KGSKGDSGMEGKSGRNGLPGAKGD---PGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGP 321
           +G KG  G +GK G +G+ G KG+   PG+ G KG  G  G+ GP GPKGD G  G++G 
Sbjct: 313 RGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGE 372

Query: 322 TGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPPPNIPIKFEKILYNDQGNYSP 375
            G+ G+ G  G  G       S       +P PP       EK    D+GN  P
Sbjct: 373 KGEPGADGEAGRPGSSG---PSGDEGQPGEPGPPG------EKGEAGDEGNPGP 417


>gi|22027583 alpha 1 type XIII collagen isoform 7 [Homo sapiens]
          Length = 703

 Score =  194 bits (492), Expect = 2e-49
 Identities = 107/234 (45%), Positives = 131/234 (55%), Gaps = 12/234 (5%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
           +PGQ G PG  G PG KGE   +G+PGPPG         + GEKG +G+ GD G PG  G
Sbjct: 468 LPGQIGPPGAPGIPGQKGE---IGLPGPPG---------HDGEKGPRGKPGDMGPPGPQG 515

Query: 168 KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKG 227
            PG  G PG KG+ G+ G  G KG+KG  G       KGE G++G  G+ GL G PG KG
Sbjct: 516 PPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPGAEGLQGVPGPKG 575

Query: 228 EKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKG 287
           E G  G KGE G +G  GD G  G  G  G  G  G  G+ G  G+ G +G  G  G+KG
Sbjct: 576 EAGLDGAKGEKGFQGEKGDRGPLGLPGASGLDGRPGPPGTPGPIGVPGPAGPKGERGSKG 635

Query: 288 DPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVP 341
           DPG+ G  G  G PGL GP G KG+ G +G +G  G KG +G +G+ G  A  P
Sbjct: 636 DPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPCP 689



 Score =  190 bits (482), Expect = 3e-48
 Identities = 115/264 (43%), Positives = 138/264 (52%), Gaps = 42/264 (15%)

Query: 112 KGEPGETGQPGPKGEAGNLGIPGP---PGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGK 168
           +G PG  G PGP G  G+ G+PGP   PG+ GP GP+G  G +G  G +G++G+PG PGK
Sbjct: 269 QGPPGPPGPPGPSGPLGHPGLPGPMGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGK 328

Query: 169 PGAQGEPG--PKGDKGNIGLGGVKGQKGSKGD-----TCGNCTKGEKGDQ-----GAMGS 216
            GA+G PG    G KG  G+ G KG+KG++G        G   KGEKGD      G  G 
Sbjct: 329 HGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLLGQ--KGEKGDAGNSIGGGRGE 386

Query: 217 PGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDS----- 271
           PG  G PG  G KGE G  G++G  G  GD GERG  G++G  G KG KG  G       
Sbjct: 387 PGPPGLPGPPGPKGEAGVDGQVGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDY 446

Query: 272 -----------------GMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPK---G 311
                            G  G  G+ G PGA G PG KGE G  GPPG  G  GP+   G
Sbjct: 447 NGNINEALQEIRTLALMGPPGLPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPG 506

Query: 312 DIGNKGVRGPTGKKGSRGFKGSKG 335
           D+G  G +GP GK G  G KG  G
Sbjct: 507 DMGPPGPQGPPGKDGPPGVKGENG 530



 Score =  189 bits (481), Expect = 4e-48
 Identities = 117/270 (43%), Positives = 135/270 (50%), Gaps = 43/270 (15%)

Query: 103 DCCSPVPGQKGEPGET---GQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGE------KGL 153
           D  + + G +GEPG     G PGPKGEAG  G  GPPG  G +G RG  GE      KG 
Sbjct: 375 DAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDGQVGPPGQPGDKGERGAAGEQGPDGPKGS 434

Query: 154 KGERGD----------------------QGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKG 191
           KGE G                        G PG PG+ G  G PG  G KG IGL G  G
Sbjct: 435 KGEPGKGEMVDYNGNINEALQEIRTLALMGPPGLPGQIGPPGAPGIPGQKGEIGLPGPPG 494

Query: 192 QKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERG 251
             G KG        G+ G  G  G PG  G PG KGE G  G  GE G+K   G++G+ G
Sbjct: 495 HDGEKGP---RGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEK---GETGQAG 548

Query: 252 GKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPT---- 307
             G+KGE G KG  G++G  G+ G  G  GL GAKG+ G +GEKG+ GP GL G +    
Sbjct: 549 SPGEKGEAGEKGNPGAEGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGASGLDG 608

Query: 308 --GPKGDIGNKGVRGPTGKKGSRGFKGSKG 335
             GP G  G  GV GP G KG RG KG  G
Sbjct: 609 RPGPPGTPGPIGVPGPAGPKGERGSKGDPG 638



 Score =  176 bits (447), Expect = 3e-44
 Identities = 108/279 (38%), Positives = 140/279 (50%), Gaps = 35/279 (12%)

Query: 108 VPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPG 167
           V G KGEPG    PG KGE G  G PG PG++G +G +G  G   + G RG+ G PG PG
Sbjct: 339 VAGMKGEPGI---PGTKGEKGAEGSPGLPGLLGQKGEKGDAGNS-IGGGRGEPGPPGLPG 394

Query: 168 KPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGA-------------- 213
            PG +GE G  G  G  G  G KG++G+ G+   +  KG KG+ G               
Sbjct: 395 PPGPKGEAGVDGQVGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEAL 454

Query: 214 --------MGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEK 265
                   MG PGL G  G  G  G  G+KGE+G  G  G  GE+G +G+ G+ G  G +
Sbjct: 455 QEIRTLALMGPPGLPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQ 514

Query: 266 GSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKK 325
           G  G  G  G  G NG PG+ G+ G KGE G+ G PG  G  G KG+ G +G++G  G K
Sbjct: 515 GPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPGAEGLQGVPGPK 574

Query: 326 GS---------RGFKGSKGELARVPRSAFSAGLSKPFPP 355
           G          +GF+G KG+   +     S    +P PP
Sbjct: 575 GEAGLDGAKGEKGFQGEKGDRGPLGLPGASGLDGRPGPP 613



 Score =  153 bits (386), Expect = 4e-37
 Identities = 114/329 (34%), Positives = 135/329 (41%), Gaps = 61/329 (18%)

Query: 102 CDCCSPVPGQKGEPGETGQPGPKGEAGNLGIPGPPG--VVGPQGPRGYKGEKGLKGERGD 159
           C+C     G  G PG  G  G  G  G +G PG  G  ++GP+GP G  G +G  G  G 
Sbjct: 117 CNCPPAFQGPTGRPGLPGDKGAIGMPGRVGSPGDAGLSIIGPRGPPGQPGTRGFPGFPGP 176

Query: 160 QGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGD----TC--------------- 200
            G+ G PG PG +G+ G  G  G  G  G KG+KG  G+     C               
Sbjct: 177 IGLDGKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIA 236

Query: 201 -------------------GNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDK 241
                                  +GE+      G PG  G PG  G  G  G  G MG  
Sbjct: 237 LKLLPLLNSVRLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPP 296

Query: 242 GCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGL--PGAKGDPGIKGEKGELG 299
           G  G  G +G  G +G  G KGE+G  G  G  G  G  G+   G KG+PGI G KGE G
Sbjct: 297 GLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKG 356

Query: 300 P------PGLLGPTGPKGDIGNK--GVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSK 351
                  PGLLG  G KGD GN   G RG  G  G  G  G KGE          AG+  
Sbjct: 357 AEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGE----------AGVDG 406

Query: 352 PFPPPNIP-IKFEKILYNDQGNYSPVTGK 379
              PP  P  K E+    +QG   P   K
Sbjct: 407 QVGPPGQPGDKGERGAAGEQGPDGPKGSK 435



 Score =  152 bits (383), Expect = 8e-37
 Identities = 105/278 (37%), Positives = 125/278 (44%), Gaps = 64/278 (23%)

Query: 109 PGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKG---------------- 152
           PG  G  G+ G PGPKG+   +G+ GPPG  GPQG +G KG+ G                
Sbjct: 174 PGPIGLDGKPGHPGPKGD---MGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALR 230

Query: 153 ----------------------------LKGER------GDQGVPGYPGKPGAQGEPGPK 178
                                        +GE+      G  G PG PG  G  G PG  
Sbjct: 231 SSQIIALKLLPLLNSVRLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLP 290

Query: 179 GDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEM 238
           G  G  GL G  G KG  G        G KG++G  G PG HG  GA G    +   G  
Sbjct: 291 GPMGPPGLPGPPGPKGDPGI---QGYHGRKGERGMPGMPGKHGAKGAPG----IAVAGMK 343

Query: 239 GDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGEL 298
           G+ G  G  GE+G +G  G  G+ G+KG KGD+G     GR G PG  G PG  G KGE 
Sbjct: 344 GEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGR-GEPGPPGLPGPPGPKGEA 402

Query: 299 GPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGE 336
           G  G +GP G  GD   KG RG  G++G  G KGSKGE
Sbjct: 403 GVDGQVGPPGQPGD---KGERGAAGEQGPDGPKGSKGE 437



 Score = 68.9 bits (167), Expect = 9e-12
 Identities = 43/104 (41%), Positives = 48/104 (46%), Gaps = 5/104 (4%)

Query: 216 SPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEG--GMKGEKGSKGDSGM 273
           SPG +  P  +G  G  G  G   DKG  G  G  G  G  G    G +G  G  G  G 
Sbjct: 114 SPGCNCPPAFQGPTGRPGLPG---DKGAIGMPGRVGSPGDAGLSIIGPRGPPGQPGTRGF 170

Query: 274 EGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKG 317
            G  G  GL G  G PG KG+ G  GPPG  GP G KG+ G  G
Sbjct: 171 PGFPGPIGLDGKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCG 214



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 32/81 (39%), Positives = 39/81 (48%), Gaps = 5/81 (6%)

Query: 262 KGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGL--LGPTGPKGDIGNK--- 316
           K   G       +G +GR GLPG KG  G+ G  G  G  GL  +GP GP G  G +   
Sbjct: 112 KTSPGCNCPPAFQGPTGRPGLPGDKGAIGMPGRVGSPGDAGLSIIGPRGPPGQPGTRGFP 171

Query: 317 GVRGPTGKKGSRGFKGSKGEL 337
           G  GP G  G  G  G KG++
Sbjct: 172 GFPGPIGLDGKPGHPGPKGDM 192


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.138    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,116,496
Number of Sequences: 37866
Number of extensions: 1723979
Number of successful extensions: 63575
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 278
Number of HSP's successfully gapped in prelim test: 415
Number of HSP's that attempted gapping in prelim test: 6508
Number of HSP's gapped (non-prelim): 7574
length of query: 477
length of database: 18,247,518
effective HSP length: 106
effective length of query: 371
effective length of database: 14,233,722
effective search space: 5280710862
effective search space used: 5280710862
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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