Guide to the Human Genome
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Search of human proteins with 25777671

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
sapiens]
         (940 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s...  1999   0.0  
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     129   1e-29
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   119   2e-26
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   119   2e-26
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...   118   2e-26
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...   118   2e-26
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...   118   2e-26
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]               117   5e-26
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]      116   9e-26
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     115   2e-25
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]              115   2e-25
gi|48762934 alpha 2 type I collagen [Homo sapiens]                    114   3e-25
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]        112   2e-24
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   111   4e-24
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]              108   2e-23
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]   108   2e-23
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   108   3e-23
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   108   3e-23
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   108   3e-23
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]    106   1e-22
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   106   1e-22
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      105   2e-22
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...   105   3e-22
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...   105   3e-22
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...   105   3e-22
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...   105   3e-22
gi|119829187 alpha 1 type XVII collagen [Homo sapiens]                104   3e-22
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]    104   3e-22
gi|119508426 alpha 3 type IX collagen [Homo sapiens]                  104   4e-22
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   103   6e-22

>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
           sapiens]
          Length = 940

 Score = 1999 bits (5179), Expect = 0.0
 Identities = 940/940 (100%), Positives = 940/940 (100%)

Query: 1   MGSGPIDPKELLKGLDSFLNRDGEVKSVDGISKIFSLMKEARKMVSRCTYLNILLQTRSP 60
           MGSGPIDPKELLKGLDSFLNRDGEVKSVDGISKIFSLMKEARKMVSRCTYLNILLQTRSP
Sbjct: 1   MGSGPIDPKELLKGLDSFLNRDGEVKSVDGISKIFSLMKEARKMVSRCTYLNILLQTRSP 60

Query: 61  EILVKFIDVGGYKLLNNWLTYSKTTNNIPLLQQILLTLQHLPLTVDHLKQNNTAKLVKQL 120
           EILVKFIDVGGYKLLNNWLTYSKTTNNIPLLQQILLTLQHLPLTVDHLKQNNTAKLVKQL
Sbjct: 61  EILVKFIDVGGYKLLNNWLTYSKTTNNIPLLQQILLTLQHLPLTVDHLKQNNTAKLVKQL 120

Query: 121 SKSSEDEELRKLASVLVSDWMAVIRSQSSTQPAEKDKKKRKDEGKSRTTLPERPLTEVKA 180
           SKSSEDEELRKLASVLVSDWMAVIRSQSSTQPAEKDKKKRKDEGKSRTTLPERPLTEVKA
Sbjct: 121 SKSSEDEELRKLASVLVSDWMAVIRSQSSTQPAEKDKKKRKDEGKSRTTLPERPLTEVKA 180

Query: 181 ETRAEEAPEKKREKPKSLRTTAPSHAKFRSTGLELETPSLVPVKKNASTVVVSDKYNLKP 240
           ETRAEEAPEKKREKPKSLRTTAPSHAKFRSTGLELETPSLVPVKKNASTVVVSDKYNLKP
Sbjct: 181 ETRAEEAPEKKREKPKSLRTTAPSHAKFRSTGLELETPSLVPVKKNASTVVVSDKYNLKP 240

Query: 241 IPLKRQSNVAAPGDATPPAEKKYKPLNTTPNATKEIKVKIIPPQPMEGLGFLDALNSAPV 300
           IPLKRQSNVAAPGDATPPAEKKYKPLNTTPNATKEIKVKIIPPQPMEGLGFLDALNSAPV
Sbjct: 241 IPLKRQSNVAAPGDATPPAEKKYKPLNTTPNATKEIKVKIIPPQPMEGLGFLDALNSAPV 300

Query: 301 PGIKIKKKKKVLSPTAAKPSPFEGKTSTEPSTAKPSSPEPAPPSEAMDADRPGTPVPPVE 360
           PGIKIKKKKKVLSPTAAKPSPFEGKTSTEPSTAKPSSPEPAPPSEAMDADRPGTPVPPVE
Sbjct: 301 PGIKIKKKKKVLSPTAAKPSPFEGKTSTEPSTAKPSSPEPAPPSEAMDADRPGTPVPPVE 360

Query: 361 VPELMDTASLEPGALDAKPVESPGDPNQLTRKGRKRKSVTWPEEGKLREYFYFELDETER 420
           VPELMDTASLEPGALDAKPVESPGDPNQLTRKGRKRKSVTWPEEGKLREYFYFELDETER
Sbjct: 361 VPELMDTASLEPGALDAKPVESPGDPNQLTRKGRKRKSVTWPEEGKLREYFYFELDETER 420

Query: 421 VNVNKIKDFGEAAKREILSDRHAFETARRLSHDNMEEKVPWVCPRPLVLPSPLVTPGSNS 480
           VNVNKIKDFGEAAKREILSDRHAFETARRLSHDNMEEKVPWVCPRPLVLPSPLVTPGSNS
Sbjct: 421 VNVNKIKDFGEAAKREILSDRHAFETARRLSHDNMEEKVPWVCPRPLVLPSPLVTPGSNS 480

Query: 481 QERYIQAEREKGILQELFLNKESPHEPDPEPYEPIPPKLIPLDEECSMDETPYVETLEPG 540
           QERYIQAEREKGILQELFLNKESPHEPDPEPYEPIPPKLIPLDEECSMDETPYVETLEPG
Sbjct: 481 QERYIQAEREKGILQELFLNKESPHEPDPEPYEPIPPKLIPLDEECSMDETPYVETLEPG 540

Query: 541 GSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSEEL 600
           GSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSEEL
Sbjct: 541 GSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSEEL 600

Query: 601 LKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGPHGGPGG 660
           LKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGPHGGPGG
Sbjct: 601 LKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGPHGGPGG 660

Query: 661 PVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPP 720
           PVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPP
Sbjct: 661 PVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPP 720

Query: 721 PFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSG 780
           PFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSG
Sbjct: 721 PFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSG 780

Query: 781 HRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMG 840
           HRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMG
Sbjct: 781 HRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMG 840

Query: 841 GSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDGGH 900
           GSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDGGH
Sbjct: 841 GSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDGGH 900

Query: 901 SHGGDMSNRPVCRHFMMKGNCRYENNCAFYHPGVNGPPLP 940
           SHGGDMSNRPVCRHFMMKGNCRYENNCAFYHPGVNGPPLP
Sbjct: 901 SHGGDMSNRPVCRHFMMKGNCRYENNCAFYHPGVNGPPLP 940


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  129 bits (325), Expect = 1e-29
 Identities = 143/415 (34%), Positives = 163/415 (39%), Gaps = 72/415 (17%)

Query: 539 PGGSG-----GSPDGAG--GSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGS 591
           PGG G     GSP G G  G   PP      GS G    P  PG  G   Q     +MG 
Sbjct: 530 PGGPGMRGMPGSPGGPGSDGKPGPP------GSQGESGRPGPPGPSGPRGQP---GVMGF 580

Query: 592 PNSHPSEELLKQ-----------PDYSDKIKQMLVPHGLLGPGPIANGFPPG--GPGGPK 638
           P    ++    +           P           P G   PGP   G   G  GP GP+
Sbjct: 581 PGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQG--PPGPTGPGGDKGDTGPPGPQ 638

Query: 639 GMQHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRG-GDPFWDGPGDP--MRGGP-MRG 694
           G+Q  P G GGP PG +G PG P      G P  P G GD    G   P  + G P +RG
Sbjct: 639 GLQGLP-GTGGP-PGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRG 696

Query: 695 GPGPGPGPYHRGRGGRGGNEPPPPPPP--------FRGARGGRSGGGPPNGRGGPGG--- 743
           G GP PGP     GG+G   PP PP            G RGG    GP   +G PGG   
Sbjct: 697 GAGP-PGP----EGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGA 751

Query: 744 -GMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMG----------SGHRPHEGPGGSMG 792
            G+ G  G R   GP G  G  +G    +G GG  G           G R   GP G  G
Sbjct: 752 DGVPGKDGPRGPTGPIGPPG-PAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAG 810

Query: 793 GGGGHRPHEGPGG-GISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGP 851
             G    +  PGG G  G  G +   GP G  G  GG  P  GP G  G  G      GP
Sbjct: 811 FPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGP-AGPPGPQGVKGERGSPGGP 869

Query: 852 GHGGPHGHRPHDVPGHRG-HDHRGPP-PHEHRGHDGPGHGGGGHRGHDGGHSHGG 904
           G  G  G R   +PG  G + + GPP P    G DGP  G  G+ G  G     G
Sbjct: 870 GAAGFPGAR--GLPGPPGSNGNPGPPGPSGSPGKDGP-PGPAGNTGAPGSPGVSG 921



 Score =  123 bits (309), Expect = 7e-28
 Identities = 143/463 (30%), Positives = 169/463 (36%), Gaps = 108/463 (23%)

Query: 516 PPKLIPLDEECSM-DETPYVETLEPGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGP 574
           P   IP  E C++  + P   T  P G G  P G  G   PP +    G  G    P  P
Sbjct: 75  PNPEIPFGECCAVCPQPPTAPTRPPNGQG--PQGPKGDPGPPGIPGRNGDPGIPGQPGSP 132

Query: 575 GGGGINVQEILTSIMGSPNSHPSEELLKQPDY-SDKIKQMLVPHGLLGPGPIANGFPPGG 633
           G  G           G   S P+      P Y S  +K  +   GL G       +P  G
Sbjct: 133 GSPGPP---------GICESCPTGPQNYSPQYDSYDVKSGVAVGGLAG-------YP--G 174

Query: 634 PGGPKGMQHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMR 693
           P GP G    PPGP    PG  G PG P  P   GPP     G+P   GP  P  G P  
Sbjct: 175 PAGPPG----PPGP----PGTSGHPGSPGSPGYQGPP-----GEPGQAGPSGPP-GPPGA 220

Query: 694 GGP-GPGPGPYHRGRGGRGGNEPPPPPPPFRGARG--------------GRSG------- 731
            GP GP       GR GR G    P PP  +G  G              GR+G       
Sbjct: 221 IGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGA 280

Query: 732 ---------------GGPPNGRGGPG----GGMVGGGGHRPHEGPGGGMGNSSGHRPHEG 772
                           GP   RG PG     G+ G  G R ++G  G  G      P  G
Sbjct: 281 PGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGP-PG 339

Query: 773 PGGGMGS-GHRPHEGPGGSMGGGG-----------GHRPHEGPGG--GISGGSGHRPHEG 818
             G  GS G +   GP GS G  G           GH   +GP G  GI+G  G +   G
Sbjct: 340 TAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMG 399

Query: 819 PGGGMGAGG--GHRPHEGPGGS------MGGSGGHRPHEGPGHGGPHGHRPH----DVPG 866
           P G  GA G  G R   GP G+       GG+G    +   G  GP G R       VPG
Sbjct: 400 PAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPG 459

Query: 867 HRGHDHRGPPPHEHRGHDGPG----HGGGGHRGHDGGHSHGGD 905
            +G D +   P E   +  PG     G  G RG  G +   G+
Sbjct: 460 AKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGE 502



 Score =  122 bits (305), Expect = 2e-27
 Identities = 142/422 (33%), Positives = 156/422 (36%), Gaps = 98/422 (23%)

Query: 539 PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGP--QGPGGGGINVQEILTSIMGSPNSHP 596
           PG  G   DG  GS   P    L G+ G    P  +GP G               PN  P
Sbjct: 458 PGAKG--EDGKDGSPGEPGANGLPGAAGERGAPGFRGPAG---------------PNGIP 500

Query: 597 SEELLKQPDYSDKIKQMLVPHGLLG-PGPIANGFPPGGPGGPKGMQHFPPGPGGP----M 651
            E   K P           P G  G PG        G PGGP GM+  P  PGGP     
Sbjct: 501 GE---KGPAGERGAPGPAGPRGAAGEPGR------DGVPGGP-GMRGMPGSPGGPGSDGK 550

Query: 652 PGPHG--------GPGGPVGPRLLGPP-----PPPRGGDPFWDGPGDPMRGGPMRGGPGP 698
           PGP G        GP GP GPR  G P     P P+G D      G P + G  RGGPG 
Sbjct: 551 PGPPGSQGESGRPGPPGPSGPR--GQPGVMGFPGPKGND------GAPGKNGE-RGGPG- 600

Query: 699 GPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPN--------GRGGPGG-----GM 745
           GPGP  +G  G+ G   P  PP   G  G +   GPP         G GGP G     G 
Sbjct: 601 GPGP--QGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGE 658

Query: 746 VGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPG- 804
            G  G     G  GG G++        PG     G R   GP G  GG G   P   PG 
Sbjct: 659 PGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGA 718

Query: 805 -------------GGISGGSGHRPHEGPGGGMGAGG--GHRPHEGPGGSMGGSGGHRPHE 849
                        GG+ G  G +  +G  GG GA G  G     GP G +G  G      
Sbjct: 719 AGTPGLQGMPGERGGL-GSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPG 777

Query: 850 GPGHGGPHG----HRPHDVPGHRGHDHRGPP-PHEHRGHDGPG--HGGGGHRGHDGGHSH 902
             G GG  G      P   PG RG    GPP P    G  G     GG G RG  G    
Sbjct: 778 DKGEGGAPGLPGIAGPRGSPGERG--ETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGE 835

Query: 903 GG 904
           GG
Sbjct: 836 GG 837



 Score =  120 bits (302), Expect = 5e-27
 Identities = 138/405 (34%), Positives = 148/405 (36%), Gaps = 83/405 (20%)

Query: 538  EPGGSG--GSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSH 595
            EPGG G  G+P G  G   PP +A   G  G   GP GP G           + G   S 
Sbjct: 820  EPGGKGERGAP-GEKGEGGPPGVAGPPGGSGPA-GPPGPQG-----------VKGERGSP 866

Query: 596  PSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGPH 655
                    P             GL GP P +NG P  GP GP G     PG  GP PGP 
Sbjct: 867  GGPGAAGFPG----------ARGLPGP-PGSNGNP--GPPGPSGS----PGKDGP-PGPA 908

Query: 656  GGPGGPVGPRLLGPP----PPPRGGDPFWDGP-GDP-------------MRGGPMRGGPG 697
            G  G P  P + GP      P   G P   GP G P             + G P   GP 
Sbjct: 909  GNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPR 968

Query: 698  PGPGPY-------HRGRGGRGGNEPPPPP---PPFRGARGGRSGGGPPNGRGGPG-GGMV 746
              PGP          G  G  G   PP P   P   G  G     G P   G PG  G  
Sbjct: 969  GSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSP 1028

Query: 747  GGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMG-SGHRPHEGPGGSMG--GGGGHRPHEGP 803
            GG G R   G  G  G + GH    GP G  G SG R   GP G  G  G  G R   GP
Sbjct: 1029 GGKGDRGENGSPGAPG-APGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGP 1087

Query: 804  GG--------GISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGG 855
             G        G  G +G + H G  G  GA G      GP G  G  G   P    G  G
Sbjct: 1088 QGPRGDKGETGERGAAGIKGHRGFPGNPGAPGS----PGPAGQQGAIGSPGPAGPRGPVG 1143

Query: 856  PHGHRPHDVPGHRGHDHR-GPP-PHEHRGHDGPGHGGGGHRGHDG 898
            P G  P    G  GH    GPP P  +RG  G   G  GH G  G
Sbjct: 1144 PSG--PPGKDGTSGHPGPIGPPGPRGNRGERG-SEGSPGHPGQPG 1185



 Score =  115 bits (288), Expect = 2e-25
 Identities = 135/397 (34%), Positives = 158/397 (39%), Gaps = 87/397 (21%)

Query: 539  PGGSGGS----PDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNS 594
            PG  GG+    P+G  G+  PP      G+ G  +G  G  GG           +GSP  
Sbjct: 692  PGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGL-QGMPGERGG-----------LGSPG- 738

Query: 595  HPSEELLKQPDYSDKIKQMLVPHGLLGP--GPIANGFP----PGGPGGPKGMQHFPPGPG 648
                                 P G  G   GP A+G P    P GP GP G    PPGP 
Sbjct: 739  ---------------------PKGDKGEPGGPGADGVPGKDGPRGPTGPIG----PPGPA 773

Query: 649  GPMPGPHGGPGGPVGPRLLGP--PPPPRG--GDPFWDG-PGDPMRGGPMRGGPGPGPGPY 703
            G  PG  G  G P  P + GP   P  RG  G P   G PG P + G   GG G    P 
Sbjct: 774  G-QPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGE-PGGKGERGAPG 831

Query: 704  HRGRGG-------RGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGG-GMVGGGGHRPHE 755
             +G GG        GG+ P  PP P +G +G R   G P   G PG  G+ G  G   + 
Sbjct: 832  EKGEGGPPGVAGPPGGSGPAGPPGP-QGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNP 890

Query: 756  GPGGGMGNSSGHRPHEGPGGGMG-------SGHRPHEGPGGSMGGGGGHRPHEGPGG-GI 807
            GP G  G S G     GP G  G       SG +   G  G  G  G   P   PG  GI
Sbjct: 891  GPPGPSG-SPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGI 949

Query: 808  SGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGH 867
            +G +G R   GP G  G  G      GP G  G SG    +   G  GP G  P  +PG 
Sbjct: 950  AGITGARGLAGPPGMPGPRGS----PGPQGVKGESGKPGANGLSGERGPPG--PQGLPGL 1003

Query: 868  RGHDHRGPPPHE-HRGHDG-PGH----GGGGHRGHDG 898
             G    G P  + + G DG PG     GG G RG +G
Sbjct: 1004 AG--TAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENG 1038



 Score =  109 bits (273), Expect = 1e-23
 Identities = 122/363 (33%), Positives = 139/363 (38%), Gaps = 51/363 (14%)

Query: 539 PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
           PG +G  P G  G   PP    L G  G G GP  PG  G   +       G+P +   +
Sbjct: 620 PGPTG--PGGDKGDTGPPGPQGLQGLPGTG-GP--PGENGKPGEPGPKGDAGAPGAPGGK 674

Query: 599 ELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGP-------- 650
                P           P GL G   +  G  P GP G KG    PPGP G         
Sbjct: 675 GDAGAPGERG-------PPGLAGAPGLRGGAGPPGPEGGKGAAG-PPGPPGAAGTPGLQG 726

Query: 651 MPGPHGGPGGPVGPR--LLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRG 708
           MPG  GG G P GP+     P  P   G P  DGP  P   GP+ G PGP   P  +G G
Sbjct: 727 MPGERGGLGSP-GPKGDKGEPGGPGADGVPGKDGPRGPT--GPI-GPPGPAGQPGDKGEG 782

Query: 709 GRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGG----GMVGGGGHRPHEGPGGGMGNS 764
           G  G      P   RG+ G R   GPP   G PG     G  GG G R   G  G  G  
Sbjct: 783 GAPGLPGIAGP---RGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPP 839

Query: 765 SGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGG-GISGGSGHRPHEGPGGGM 823
               P   PGG   +G    +G  G  G  GG      PG  G+ G  G   + GP G  
Sbjct: 840 GVAGP---PGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPS 896

Query: 824 GAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGH 883
           G+ G   P  GP G+ G  G       PG  GP G      PG +G      PP    G 
Sbjct: 897 GSPGKDGP-PGPAGNTGAPGS------PGVSGPKGDAGQ--PGEKGSPGAQGPP----GA 943

Query: 884 DGP 886
            GP
Sbjct: 944 PGP 946



 Score =  103 bits (256), Expect = 1e-21
 Identities = 104/307 (33%), Positives = 119/307 (38%), Gaps = 45/307 (14%)

Query: 633 GPGGPKGMQHFPPGPGGPMP-GPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDP-MRGG 690
           GP GP G   FP  PG     GP G PG    P   G P P +G       PG P + G 
Sbjct: 333 GPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGP-QGHAGAQGPPGPPGINGS 391

Query: 691 PM-RGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRG-----GPGG- 743
           P  +G  GP   P   G  G  G   PP P    GA G R G G P   G     GP G 
Sbjct: 392 PGGKGEMGPAGIP---GAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGE 448

Query: 744 ----GMVGGGGHRPHEGPGG--------GMGNSSGHRPHEGPGGGMGSGHRPHE-GPGGS 790
               G+ G  G +  +G  G        G+  ++G R   G  G  G    P E GP G 
Sbjct: 449 RGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGE 508

Query: 791 MGGGGGHRPHEGPG----GGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHR 846
            G  G   P    G     G+ GG G R   G  GG G+ G      GP GS G SG   
Sbjct: 509 RGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDG----KPGPPGSQGESGRPG 564

Query: 847 PHEGPGHGGPHGH-RPHDVPGHRGHDHRGPPPHEHRGHDGPG-------HGGGGHRGHDG 898
           P   PG  GP G       PG +G+D       E  G  GPG       +G  G +G  G
Sbjct: 565 P---PGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPG 621

Query: 899 GHSHGGD 905
               GGD
Sbjct: 622 PTGPGGD 628



 Score = 82.4 bits (202), Expect = 2e-15
 Identities = 100/301 (33%), Positives = 113/301 (37%), Gaps = 46/301 (15%)

Query: 541  GSGGSPDGAG--GSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
            G  GSP   G  G+  P  +A + G+ G    P  PG  G    + +    G P ++   
Sbjct: 930  GEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLS 989

Query: 599  ELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGP--KGMQHFPPGPGGPMP-GPH 655
                 P           P GL  PG       PG  G P   G+      PGG    G +
Sbjct: 990  GERGPPG----------PQGL--PGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGEN 1037

Query: 656  GGPGGPVGPRLLGPPPP--PRG--GDPFWDGPGDPMRG-GPM--RGGPGP-GPGPYHRGR 707
            G PG P  P   GPP P  P G  GD    GP  P    GP   RG PGP GP       
Sbjct: 1038 GSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGET 1097

Query: 708  GGRG-----------GNEPPPPPPPFRGARGGRSGGGPPNGRG--GPGG--GMVGGGGHR 752
            G RG           GN   P  P   G +G     GP   RG  GP G  G  G  GH 
Sbjct: 1098 GERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHP 1157

Query: 753  PHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMG---GGGGHRPHEGPGGGISG 809
               GP G  GN  G R  EG  G  G    P  GP G+ G   GG G     G GG  +G
Sbjct: 1158 GPIGPPGPRGN-RGERGSEGSPGHPGQPGPP--GPPGAPGPCCGGVGAAAIAGIGGEKAG 1214

Query: 810  G 810
            G
Sbjct: 1215 G 1215



 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 90/269 (33%), Positives = 96/269 (35%), Gaps = 49/269 (18%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSP--NSHP 596
            P GS G P G  G    P    L G  G   GPQG  G        L    G P  + +P
Sbjct: 967  PRGSPG-PQGVKGESGKPGANGLSGERGP-PGPQGLPG--------LAGTAGEPGRDGNP 1016

Query: 597  SEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFP-PGGPGGPKGMQ--HFPPGPGGPM-- 651
              + L   D S   K     +G  G  P A G P P GP GP G        GP GP   
Sbjct: 1017 GSDGLPGRDGSPGGKGDRGENGSPG-APGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGA 1075

Query: 652  PGPHGGPG--GPVGPRLLGPPPPPRG--------------GDPFWDGP-------GDPMR 688
            PGP G  G  GP GPR        RG              G P   GP       G P  
Sbjct: 1076 PGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGP 1135

Query: 689  GGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG-----G 743
             GP RG  GP   P   G  G  G   PP P   RG RG     G P   G PG     G
Sbjct: 1136 AGP-RGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPG 1194

Query: 744  GMVGGGGHRPHEGPGGGMGNSSGHRPHEG 772
               GG G     G GG    + G  P+ G
Sbjct: 1195 PCCGGVGAAAIAGIGG--EKAGGFAPYYG 1221


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score =  119 bits (297), Expect = 2e-26
 Identities = 141/429 (32%), Positives = 159/429 (37%), Gaps = 74/429 (17%)

Query: 539 PGGSG-GSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGS------ 591
           PG  G   P GA G + P  LA   G  GA   P  PG  G+     LT   G       
Sbjct: 518 PGQDGLAGPKGAPGERGPSGLA---GPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGK 574

Query: 592 --PNSHPSEELLKQPDYSDKIKQMLVPHGLLG-PGPI-ANGFP--------PGGPG---- 635
             P+  P E+    P      +      G++G PGP  ANG P        PG PG    
Sbjct: 575 VGPSGAPGEDGRPGPPGPQGARGQ---PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGL 631

Query: 636 ----GPKGMQHFPPGPGGPMP--GPHGGPGGPVGPRLLGPPPPP-RGGDPFWDG-PGDPM 687
               G  G    PPGP GP    G  G PG      L GPP PP  GG P   G PG+  
Sbjct: 632 PGKDGETGAAG-PPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA- 689

Query: 688 RGGPMRGGPGPGPG-PYHRGRGGRGGNEPP---PPPPPFRGARGGRSGGGPPNGRGGPG- 742
            G P   GP    G P  RG  G  G + P   P  P   G +G     GPP  +G PG 
Sbjct: 690 -GAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGL 748

Query: 743 GGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGG--GHRPH 800
            GM G  G     GP G  G+     P   PG   G G     GP G  G  G  G    
Sbjct: 749 QGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGP 808

Query: 801 EGPGG--GISGGSGHRPHEGPGGGMGAGG--------GHRPHEGPGGSMGGSGGHRPHEG 850
            GP G  G  G  G R   GP G  G  G        G +  +G  G  G +G   P   
Sbjct: 809 PGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGP 868

Query: 851 PGHGGPHGHRPHDVPGHRG-HDHRGPP-------------PHEHRGHDGPGHGGGGHRGH 896
            G  GP G  P  V G +G    +GPP             P    G+ GP  G  G  G 
Sbjct: 869 SGAPGPQG--PTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGP-PGPPGPSGK 925

Query: 897 DGGHSHGGD 905
           DG     GD
Sbjct: 926 DGPKGARGD 934



 Score =  109 bits (273), Expect = 1e-23
 Identities = 138/458 (30%), Positives = 168/458 (36%), Gaps = 87/458 (18%)

Query: 508 DPEPYEPIPPKLIPLDEECSMDETPYVETLEPGGSGGSPDGAGGSKLPPVLANLMGSMGA 567
           D + ++P P ++   D    + +    E ++   S   P G      P  LA   G    
Sbjct: 43  DKDVWKPEPCRICVCDTGTVLCDDIICEDVKDCLSPEIPFGECCPICPTDLATASGQ--- 99

Query: 568 GKGPQGPGGGGINVQEILTSIMGSPNSH-PSEELLKQPDYSDKIKQMLVPHGLLGPGPIA 626
             GP+G  G   ++++I+    G P    P+ E   + D  DK ++         PGP  
Sbjct: 100 -PGPKGQKGEPGDIKDIVGP-KGPPGPQGPAGEQGPRGDRGDKGEKG-------APGPRG 150

Query: 627 NGFPPGGPGGPKGMQHFPPGPGGPMPGPHG--------------------------GPGG 660
               PG PG P      PPGP GP PGP G                          GP G
Sbjct: 151 RDGEPGTPGNPG-----PPGPPGP-PGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMG 204

Query: 661 PVGPRLLGPPPP-----PRGGDPFWDGPGDPMRGGPM--RGGPGPGPGPY---HRGRGGR 710
           P+GPR  GPP P     P+G       PG+P   GPM  RG PGP   P      G+ G+
Sbjct: 205 PMGPR--GPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGK 262

Query: 711 GGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG----------GGMVGGGGHRPHEGPGGG 760
            G   PP P   RG  G     G    RG PG           G+ G  G     G  G 
Sbjct: 263 AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGP 322

Query: 761 MG--NSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEG 818
           MG     G R   GP G  G+  R ++G  G  G  G   P  GP  G  G  G +   G
Sbjct: 323 MGPRGLPGERGRTGPAGAAGA--RGNDGQPGPAGPPGPVGPAGGP--GFPGAPGAKGEAG 378

Query: 819 PGGGMGAGGGHRPHEGPG-----GSMGGSGGHRPHEGPGHGGPHGHRP-HDVPGHRGHDH 872
           P G  G  G   P   PG     G  G SG       PG  G  G       PG  G   
Sbjct: 379 PTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPG--P 436

Query: 873 RGPP-PHEHRGHDGP-GHGG----GGHRGHDGGHSHGG 904
           RGPP P    G  GP G  G     G +G  G     G
Sbjct: 437 RGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPG 474



 Score =  108 bits (270), Expect = 2e-23
 Identities = 121/387 (31%), Positives = 139/387 (35%), Gaps = 78/387 (20%)

Query: 539  PGGSGGSP--DGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHP 596
            P G  G P  DG  G+K     A   G  GA  GPQGP G      +  T + G   +  
Sbjct: 832  PAGFAGPPGADGQPGAKGEQGEAGQKGDAGA-PGPQGPSGAP--GPQGPTGVTGPKGARG 888

Query: 597  SEELLKQPDYSDKIKQMLVPHGLLG-PGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGPH 655
            ++                 P G  G PG      PPG  G P      PPGP GP     
Sbjct: 889  AQG----------------PPGATGFPGAAGRVGPPGSNGNPG-----PPGPPGP----- 922

Query: 656  GGPGGPVGPRLLGPPPPPRGGDPFWDGP-------GDPMRGGPMRGGPGPGPG------- 701
             G  GP G R     PP R G+P   GP       G+P   GP      PGP        
Sbjct: 923  SGKDGPKGARG-DSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRG 981

Query: 702  ----PYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGP 757
                P  RG  G  G   P   P  +GA G     GPP   G P  G+ G  G    EG 
Sbjct: 982  IVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPP--GLTGPAGEPGREGS 1039

Query: 758  GGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPG-GGISGGSGHRPH 816
             G  G          PG    +G +   G  G++G  G   P   PG  G +G  G R  
Sbjct: 1040 PGADG---------PPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGE 1090

Query: 817  EGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRG----HDH 872
             G  G MG         GP G+ G  G   P    G  G  G R   + GHRG       
Sbjct: 1091 AGAQGPMGP-------SGPAGARGIQGPQGPRGDKGEAGEPGER--GLKGHRGFTGLQGL 1141

Query: 873  RGPP-PHEHRGHDGPGHGGGGHRGHDG 898
             GPP P   +G  GP  G  G RG  G
Sbjct: 1142 PGPPGPSGDQGASGPA-GPSGPRGPPG 1167



 Score = 98.6 bits (244), Expect = 2e-20
 Identities = 136/441 (30%), Positives = 154/441 (34%), Gaps = 93/441 (21%)

Query: 539 PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQG-------PGGGGINVQEILTSIMGS 591
           P G  G P GA G+K         G  GA +GP+G       PG  G +       I G+
Sbjct: 361 PAGGPGFP-GAPGAKGEAGPTGARGPEGA-QGPRGEPGTPGSPGPAGASGNPGTDGIPGA 418

Query: 592 PNSHPSEELLKQPDYSDKIKQMLVPHGLLGP-GPIANGFPPG-----GPGGPKGMQHFPP 645
             S  +  +   P +    +    P G  GP GP      PG     G  GPKG     P
Sbjct: 419 KGSAGAPGIAGAPGFPGP-RGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKG----EP 473

Query: 646 GPGGPM--PGPHGGPG--------GPVGPRLLGPP----PPPRGGDPFWDGPGDPMRGGP 691
           GP GP   PGP G  G        G VGP  +GPP     P   G P  DG   P +G P
Sbjct: 474 GPAGPQGAPGPAGEEGKRGARGEPGGVGP--IGPPGERGAPGNRGFPGQDGLAGP-KGAP 530

Query: 692 MRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARG--GRSGGGPPNGRGGPGGGMVGGG 749
              GP    GP      G  G+   P  P   GARG  GR G   P G+ GP G   G  
Sbjct: 531 GERGPSGLAGPK-----GANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAP-GED 584

Query: 750 GHRPHEGPGGGMGNSSGHRPHEGPGGGMGS-------------GHRPHEGPGGSMGGGGG 796
           G     GP G  G   G     GP G  G              G R   G  G  G  G 
Sbjct: 585 GRPGPPGPQGARGQP-GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP 643

Query: 797 HRPHEGPGG-----GISGGSGHRPHEGPGGGMGAGG--------------------GHRP 831
             P  GP G     G  G SG +   GP G  G GG                    G R 
Sbjct: 644 PGP-AGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERG 702

Query: 832 HEGPGGSMGGSGGHRPHEGPGHGGPHGHR----PHDVPGHRGHDHRGPPPHEH--RGHDG 885
             G  GS G  G   P   PG  G  G +    P   PG +G       P E    G  G
Sbjct: 703 FPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAG 762

Query: 886 P--GHGGGGHRGHDGGHSHGG 904
           P    G  G +G +G     G
Sbjct: 763 PKGDRGDVGEKGPEGAPGKDG 783



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 128/418 (30%), Positives = 146/418 (34%), Gaps = 86/418 (20%)

Query: 542 SGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSEELL 601
           +GG  + AGG++L  V+   MG MG  +GP GP G             G+P   P E  +
Sbjct: 184 AGGFDEKAGGAQLG-VMQGPMGPMGP-RGPPGPAGAPGP-----QGFQGNPGE-PGEPGV 235

Query: 602 KQPDYSDKIKQMLVPHGLLGP----GPIANGFPPG-----GPGGPKGMQHFPPGPGGP-- 650
             P         + P G  GP    G       PG     GP GP+G + FP  PG P  
Sbjct: 236 SGP---------MGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGV 286

Query: 651 --------------------------MPGPHGGPGGPVGPRLLGPPPPPRG--------- 675
                                      PG +G PG P+GPR L   P  RG         
Sbjct: 287 KGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPG-PMGPRGL---PGERGRTGPAGAAG 342

Query: 676 -----GDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRS 730
                G P   GP  P+  GP  GGPG    P  +G  G  G   P      RG  G   
Sbjct: 343 ARGNDGQPGPAGPPGPV--GP-AGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPG 399

Query: 731 GGGPPNGRGGPG-GGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGS-GHRPHEGPG 788
             GP    G PG  G+ G  G     G  G  G   G R   GP G  G  G +   G  
Sbjct: 400 SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPG-FPGPRGPPGPQGATGPLGPKGQTGEP 458

Query: 789 GSMGGGGGHRPHEGPG-GGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRP 847
           G  G  G   P   PG  G  G  G    EG  G  G  GG  P  GP G  G  G    
Sbjct: 459 GIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGP-IGPPGERGAPGN--- 514

Query: 848 HEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGG-GGHRGHDGGHSHGG 904
              PG  G  G  P   PG RG      P   +     PG  G  G RG  G     G
Sbjct: 515 RGFPGQDGLAG--PKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAG 570



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 94/275 (34%), Positives = 101/275 (36%), Gaps = 53/275 (19%)

Query: 538  EPGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPS 597
            EPG  G    GA G + PP             GP GP G        LT   G P    S
Sbjct: 1003 EPGKQGAP--GASGDRGPP-------------GPVGPPG--------LTGPAGEPGREGS 1039

Query: 598  EELLKQP--DYSDKIKQMLVPHGLLGPGPIANGFPPGGPG--GPKGMQ--HFPPGPGGPM 651
                  P  D +  +K      G +G  P A G PPG PG  GP G Q      G  GPM
Sbjct: 1040 PGADGPPGRDGAAGVKGDRGETGAVG-APGAPG-PPGSPGPAGPTGKQGDRGEAGAQGPM 1097

Query: 652  PGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRG 711
                 GP GP G R +  P  PRG       PG+       RG  G      HRG  G  
Sbjct: 1098 -----GPSGPAGARGIQGPQGPRGDKGEAGEPGE-------RGLKG------HRGFTGLQ 1139

Query: 712  GNEPPPPPPPFRGARG--GRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRP 769
            G   PP P   +GA G  G SG   P G  GP  G  G  G     GP G  G S    P
Sbjct: 1140 GLPGPPGPSGDQGASGPAGPSGPRGPPGPVGP-SGKDGANGIPGPIGPPGPRGRSGETGP 1198

Query: 770  HEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHE-GP 803
               PG     G     GPG  M    G  P E GP
Sbjct: 1199 AGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGP 1233



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 57/177 (32%), Positives = 64/177 (36%), Gaps = 52/177 (29%)

Query: 539  PGGSG--GSPDGAG--GSKLPPVLANLMGSMGAG--------KGPQGPGGG--------- 577
            PG  G  GSP  AG  G +     A   G MG          +GPQGP G          
Sbjct: 1067 PGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGE 1126

Query: 578  -GINVQEILTSIMGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLGP-GPI-------ANG 628
             G+      T + G P           P           P G  GP GP+       ANG
Sbjct: 1127 RGLKGHRGFTGLQGLPGP-------PGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANG 1179

Query: 629  FP-PGGPGGPKGMQHFPPGPGGPM--PGPHGGPGGP-----------VGPRLLGPPP 671
             P P GP GP+G      GP GP   PGP G PG P           +GPR  GP P
Sbjct: 1180 IPGPIGPPGPRGRSG-ETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDP 1235


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score =  119 bits (297), Expect = 2e-26
 Identities = 141/429 (32%), Positives = 159/429 (37%), Gaps = 74/429 (17%)

Query: 539 PGGSG-GSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGS------ 591
           PG  G   P GA G + P  LA   G  GA   P  PG  G+     LT   G       
Sbjct: 449 PGQDGLAGPKGAPGERGPSGLA---GPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGK 505

Query: 592 --PNSHPSEELLKQPDYSDKIKQMLVPHGLLG-PGPI-ANGFP--------PGGPG---- 635
             P+  P E+    P      +      G++G PGP  ANG P        PG PG    
Sbjct: 506 VGPSGAPGEDGRPGPPGPQGARGQ---PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGL 562

Query: 636 ----GPKGMQHFPPGPGGPMP--GPHGGPGGPVGPRLLGPPPPP-RGGDPFWDG-PGDPM 687
               G  G    PPGP GP    G  G PG      L GPP PP  GG P   G PG+  
Sbjct: 563 PGKDGETGAAG-PPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA- 620

Query: 688 RGGPMRGGPGPGPG-PYHRGRGGRGGNEPP---PPPPPFRGARGGRSGGGPPNGRGGPG- 742
            G P   GP    G P  RG  G  G + P   P  P   G +G     GPP  +G PG 
Sbjct: 621 -GAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGL 679

Query: 743 GGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGG--GHRPH 800
            GM G  G     GP G  G+     P   PG   G G     GP G  G  G  G    
Sbjct: 680 QGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGP 739

Query: 801 EGPGG--GISGGSGHRPHEGPGGGMGAGG--------GHRPHEGPGGSMGGSGGHRPHEG 850
            GP G  G  G  G R   GP G  G  G        G +  +G  G  G +G   P   
Sbjct: 740 PGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGP 799

Query: 851 PGHGGPHGHRPHDVPGHRG-HDHRGPP-------------PHEHRGHDGPGHGGGGHRGH 896
            G  GP G  P  V G +G    +GPP             P    G+ GP  G  G  G 
Sbjct: 800 SGAPGPQG--PTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGP-PGPPGPSGK 856

Query: 897 DGGHSHGGD 905
           DG     GD
Sbjct: 857 DGPKGARGD 865



 Score =  108 bits (270), Expect = 2e-23
 Identities = 121/387 (31%), Positives = 139/387 (35%), Gaps = 78/387 (20%)

Query: 539  PGGSGGSP--DGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHP 596
            P G  G P  DG  G+K     A   G  GA  GPQGP G      +  T + G   +  
Sbjct: 763  PAGFAGPPGADGQPGAKGEQGEAGQKGDAGA-PGPQGPSGAP--GPQGPTGVTGPKGARG 819

Query: 597  SEELLKQPDYSDKIKQMLVPHGLLG-PGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGPH 655
            ++                 P G  G PG      PPG  G P      PPGP GP     
Sbjct: 820  AQG----------------PPGATGFPGAAGRVGPPGSNGNPG-----PPGPPGP----- 853

Query: 656  GGPGGPVGPRLLGPPPPPRGGDPFWDGP-------GDPMRGGPMRGGPGPGPG------- 701
             G  GP G R     PP R G+P   GP       G+P   GP      PGP        
Sbjct: 854  SGKDGPKGARG-DSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRG 912

Query: 702  ----PYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGP 757
                P  RG  G  G   P   P  +GA G     GPP   G P  G+ G  G    EG 
Sbjct: 913  IVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPP--GLTGPAGEPGREGS 970

Query: 758  GGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPG-GGISGGSGHRPH 816
             G  G          PG    +G +   G  G++G  G   P   PG  G +G  G R  
Sbjct: 971  PGADG---------PPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGE 1021

Query: 817  EGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRG----HDH 872
             G  G MG         GP G+ G  G   P    G  G  G R   + GHRG       
Sbjct: 1022 AGAQGPMGP-------SGPAGARGIQGPQGPRGDKGEAGEPGER--GLKGHRGFTGLQGL 1072

Query: 873  RGPP-PHEHRGHDGPGHGGGGHRGHDG 898
             GPP P   +G  GP  G  G RG  G
Sbjct: 1073 PGPPGPSGDQGASGPA-GPSGPRGPPG 1098



 Score =  108 bits (269), Expect = 3e-23
 Identities = 126/396 (31%), Positives = 147/396 (37%), Gaps = 83/396 (20%)

Query: 570 GPQGPGGGGINVQEILTSIMGSPNSH-PSEELLKQPDYSDKIKQMLVPHGLLGPGPIANG 628
           GP+G  G   ++++I+    G P    P+ E   + D  DK ++         PGP    
Sbjct: 32  GPKGQKGEPGDIKDIVGP-KGPPGPQGPAGEQGPRGDRGDKGEKG-------APGPRGRD 83

Query: 629 FPPGGPGGPKGMQHFPPGPGGPMPGPHG--------------------------GPGGPV 662
             PG PG P      PPGP GP PGP G                          GP GP+
Sbjct: 84  GEPGTPGNPG-----PPGPPGP-PGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM 137

Query: 663 GPRLLGPPPP-----PRGGDPFWDGPGDPMRGGPM--RGGPGPGPGPY---HRGRGGRGG 712
           GPR  GPP P     P+G       PG+P   GPM  RG PGP   P      G+ G+ G
Sbjct: 138 GPR--GPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAG 195

Query: 713 NEPPPPPPPFRGARGGRSGGGPPNGRGGPG----------GGMVGGGGHRPHEGPGGGMG 762
              PP P   RG  G     G    RG PG           G+ G  G     G  G MG
Sbjct: 196 ERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMG 255

Query: 763 --NSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPG 820
                G R   GP G  G+  R ++G  G  G  G   P  GP  G  G  G +   GP 
Sbjct: 256 PRGLPGERGRTGPAGAAGA--RGNDGQPGPAGPPGPVGPAGGP--GFPGAPGAKGEAGPT 311

Query: 821 GGMGAGGGHRPHEGPG-----GSMGGSGGHRPHEGPGHGGPHGHRP-HDVPGHRGHDHRG 874
           G  G  G   P   PG     G  G SG       PG  G  G       PG  G   RG
Sbjct: 312 GARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPG--PRG 369

Query: 875 PP-PHEHRGHDGP-GHGG----GGHRGHDGGHSHGG 904
           PP P    G  GP G  G     G +G  G     G
Sbjct: 370 PPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPG 405



 Score = 98.6 bits (244), Expect = 2e-20
 Identities = 136/441 (30%), Positives = 154/441 (34%), Gaps = 93/441 (21%)

Query: 539 PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQG-------PGGGGINVQEILTSIMGS 591
           P G  G P GA G+K         G  GA +GP+G       PG  G +       I G+
Sbjct: 292 PAGGPGFP-GAPGAKGEAGPTGARGPEGA-QGPRGEPGTPGSPGPAGASGNPGTDGIPGA 349

Query: 592 PNSHPSEELLKQPDYSDKIKQMLVPHGLLGP-GPIANGFPPG-----GPGGPKGMQHFPP 645
             S  +  +   P +    +    P G  GP GP      PG     G  GPKG     P
Sbjct: 350 KGSAGAPGIAGAPGFPGP-RGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKG----EP 404

Query: 646 GPGGPM--PGPHGGPG--------GPVGPRLLGPP----PPPRGGDPFWDGPGDPMRGGP 691
           GP GP   PGP G  G        G VGP  +GPP     P   G P  DG   P +G P
Sbjct: 405 GPAGPQGAPGPAGEEGKRGARGEPGGVGP--IGPPGERGAPGNRGFPGQDGLAGP-KGAP 461

Query: 692 MRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARG--GRSGGGPPNGRGGPGGGMVGGG 749
              GP    GP      G  G+   P  P   GARG  GR G   P G+ GP G   G  
Sbjct: 462 GERGPSGLAGPK-----GANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAP-GED 515

Query: 750 GHRPHEGPGGGMGNSSGHRPHEGPGGGMGS-------------GHRPHEGPGGSMGGGGG 796
           G     GP G  G   G     GP G  G              G R   G  G  G  G 
Sbjct: 516 GRPGPPGPQGARGQP-GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP 574

Query: 797 HRPHEGPGG-----GISGGSGHRPHEGPGGGMGAGG--------------------GHRP 831
             P  GP G     G  G SG +   GP G  G GG                    G R 
Sbjct: 575 PGP-AGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERG 633

Query: 832 HEGPGGSMGGSGGHRPHEGPGHGGPHGHR----PHDVPGHRGHDHRGPPPHEH--RGHDG 885
             G  GS G  G   P   PG  G  G +    P   PG +G       P E    G  G
Sbjct: 634 FPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAG 693

Query: 886 P--GHGGGGHRGHDGGHSHGG 904
           P    G  G +G +G     G
Sbjct: 694 PKGDRGDVGEKGPEGAPGKDG 714



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 128/418 (30%), Positives = 146/418 (34%), Gaps = 86/418 (20%)

Query: 542 SGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSEELL 601
           +GG  + AGG++L  V+   MG MG  +GP GP G             G+P   P E  +
Sbjct: 115 AGGFDEKAGGAQLG-VMQGPMGPMGP-RGPPGPAGAPGP-----QGFQGNPGE-PGEPGV 166

Query: 602 KQPDYSDKIKQMLVPHGLLGP----GPIANGFPPG-----GPGGPKGMQHFPPGPGGP-- 650
             P         + P G  GP    G       PG     GP GP+G + FP  PG P  
Sbjct: 167 SGP---------MGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGV 217

Query: 651 --------------------------MPGPHGGPGGPVGPRLLGPPPPPRG--------- 675
                                      PG +G PG P+GPR L   P  RG         
Sbjct: 218 KGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPG-PMGPRGL---PGERGRTGPAGAAG 273

Query: 676 -----GDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRS 730
                G P   GP  P+  GP  GGPG    P  +G  G  G   P      RG  G   
Sbjct: 274 ARGNDGQPGPAGPPGPV--GP-AGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPG 330

Query: 731 GGGPPNGRGGPG-GGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGS-GHRPHEGPG 788
             GP    G PG  G+ G  G     G  G  G   G R   GP G  G  G +   G  
Sbjct: 331 SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPG-FPGPRGPPGPQGATGPLGPKGQTGEP 389

Query: 789 GSMGGGGGHRPHEGPG-GGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRP 847
           G  G  G   P   PG  G  G  G    EG  G  G  GG  P  GP G  G  G    
Sbjct: 390 GIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGP-IGPPGERGAPGN--- 445

Query: 848 HEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGG-GGHRGHDGGHSHGG 904
              PG  G  G  P   PG RG      P   +     PG  G  G RG  G     G
Sbjct: 446 RGFPGQDGLAG--PKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAG 501



 Score = 82.8 bits (203), Expect = 1e-15
 Identities = 102/319 (31%), Positives = 113/319 (35%), Gaps = 66/319 (20%)

Query: 622 PGPIANGFPPGGPG---GPKGMQHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDP 678
           PGP      PG      GPKG    PPGP GP      GP G  G +     P PRG D 
Sbjct: 31  PGPKGQKGEPGDIKDIVGPKG----PPGPQGP--AGEQGPRGDRGDKGEKGAPGPRGRD- 83

Query: 679 FWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGG---------- 728
               PG P       G PGP PG              PP PP   G  G           
Sbjct: 84  --GEPGTP-------GNPGP-PG--------------PPGPPGPPGLGGNFAAQMAGGFD 119

Query: 729 -RSGG----------GPPNGRGGPG-GGMVGGGGHRPHEGPGG--GMGNSSGHRPHEGPG 774
            ++GG          GP   RG PG  G  G  G + + G  G  G+    G R   GP 
Sbjct: 120 EKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPP 179

Query: 775 GGMG-SGHRPHEGPGGSMGGGGGHRPHEGPG-GGISGGSGHRPHEGPGGGMGAGG--GHR 830
           G  G  G     G  G  G  G       PG  G+ G  GHR + G  G  G  G  G +
Sbjct: 180 GKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVK 239

Query: 831 PHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGG 890
              G  G  G  G   P   PG  G  G  P    G RG+D + P P    G  GP  GG
Sbjct: 240 GESGSPGENGSPGPMGPRGLPGERGRTG--PAGAAGARGNDGQ-PGPAGPPGPVGPA-GG 295

Query: 891 GGHRGHDGGHSHGGDMSNR 909
            G  G  G     G    R
Sbjct: 296 PGFPGAPGAKGEAGPTGAR 314



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 94/275 (34%), Positives = 101/275 (36%), Gaps = 53/275 (19%)

Query: 538  EPGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPS 597
            EPG  G    GA G + PP             GP GP G        LT   G P    S
Sbjct: 934  EPGKQGAP--GASGDRGPP-------------GPVGPPG--------LTGPAGEPGREGS 970

Query: 598  EELLKQP--DYSDKIKQMLVPHGLLGPGPIANGFPPGGPG--GPKGMQ--HFPPGPGGPM 651
                  P  D +  +K      G +G  P A G PPG PG  GP G Q      G  GPM
Sbjct: 971  PGADGPPGRDGAAGVKGDRGETGAVG-APGAPG-PPGSPGPAGPTGKQGDRGEAGAQGPM 1028

Query: 652  PGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRG 711
                 GP GP G R +  P  PRG       PG+       RG  G      HRG  G  
Sbjct: 1029 -----GPSGPAGARGIQGPQGPRGDKGEAGEPGE-------RGLKG------HRGFTGLQ 1070

Query: 712  GNEPPPPPPPFRGARG--GRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRP 769
            G   PP P   +GA G  G SG   P G  GP  G  G  G     GP G  G S    P
Sbjct: 1071 GLPGPPGPSGDQGASGPAGPSGPRGPPGPVGP-SGKDGANGIPGPIGPPGPRGRSGETGP 1129

Query: 770  HEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHE-GP 803
               PG     G     GPG  M    G  P E GP
Sbjct: 1130 AGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGP 1164



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 57/177 (32%), Positives = 64/177 (36%), Gaps = 52/177 (29%)

Query: 539  PGGSG--GSPDGAG--GSKLPPVLANLMGSMGAG--------KGPQGPGGG--------- 577
            PG  G  GSP  AG  G +     A   G MG          +GPQGP G          
Sbjct: 998  PGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGE 1057

Query: 578  -GINVQEILTSIMGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLGP-GPI-------ANG 628
             G+      T + G P           P           P G  GP GP+       ANG
Sbjct: 1058 RGLKGHRGFTGLQGLPGP-------PGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANG 1110

Query: 629  FP-PGGPGGPKGMQHFPPGPGGPM--PGPHGGPGGP-----------VGPRLLGPPP 671
             P P GP GP+G      GP GP   PGP G PG P           +GPR  GP P
Sbjct: 1111 IPGPIGPPGPRGRSG-ETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDP 1166


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score =  118 bits (296), Expect = 2e-26
 Identities = 159/499 (31%), Positives = 183/499 (36%), Gaps = 98/499 (19%)

Query: 513  EPIPPKLIPLDEECSMDETP-YVETLEPGGSGGSPD--GAGGSKLPPVLANLMGSMGAGK 569
            +P PP L+    +  +   P Y     P GS G P   GA G K    L+   G  G  +
Sbjct: 696  DPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGE-R 754

Query: 570  GPQGPGGGGINVQEILTSIMGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLG----PGPI 625
            GP GP G               P     +   K     D       PHG  G    PGP 
Sbjct: 755  GPTGPRG------------QRGPRGATGKSGAKGTSGGDG------PHGPPGERGLPGPQ 796

Query: 626  A-NGFP-PGGPGGPKGMQHFPPGPG-----------GPMPGPHG--------GPGGPVGP 664
              NGFP P GP GP G    P  PG           GP PGP G        G  GP+G 
Sbjct: 797  GPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGP-PGPPGVVGPQGAAGETGPMGE 855

Query: 665  R-LLGPPPPP-------------RGGDPFWDGPGDPMRGGP--MRGGPGPGPGPYHRGRG 708
            R   GPP PP               GDP    PG P + GP  +RG PG    P   G  
Sbjct: 856  RGHPGPPGPPGEQGLPGTAGKEGTKGDP--GPPGAPGKDGPAGLRGFPGERGLPGTAGGP 913

Query: 709  GRGGNEPPPPPPPFRGA---RGGRSGGGP--PNGRGGPGG--GMVGGGGHRPHEGPGGGM 761
            G  GNE P  PP   G+   RG    GGP  P GR GP G  G  G  G    +GP G  
Sbjct: 914  GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPT 973

Query: 762  GNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGG-----GHRPHEGPGG----------- 805
            G      P   PG     G    +G  G +G  G     G++   GP G           
Sbjct: 974  GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQP 1033

Query: 806  GISGGSGHRPHEGPGGGMGAGG--GHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHD 863
            G +G  G     GP G  GA G  G R   GP G +G  G   P    G  G  G  P  
Sbjct: 1034 GAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVG--PMG 1091

Query: 864  VPGHRGHDHRGPP-PHEHRGHDGPGHGGGGHRGHDGGHSHGGDMSNRPVCRHFMMKG-NC 921
             PG  G   RGP  P+   G  GP  GG G+ G  G     G+  +  +     +KG   
Sbjct: 1092 PPGPPG--PRGPAGPNGADGPQGP-PGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG 1148

Query: 922  RYENNCAFYHPGVNGPPLP 940
                      PG  GPP P
Sbjct: 1149 ERGEKGESGQPGEPGPPGP 1167



 Score =  102 bits (253), Expect = 2e-21
 Identities = 138/461 (29%), Positives = 167/461 (36%), Gaps = 103/461 (22%)

Query: 504 PHEPDPEPYEPIPPKLIPLDEECSMDETPYVETLEPGGSGGSPDGAGGSKLPPVLANLMG 563
           P   +P+  +P P       EE  + E+  +  LE    G  P G  G K  P +     
Sbjct: 258 PQNQEPQSQDPTP------GEEEEILESSLLPPLEEAAHG--PRGLKGEKGEPAVLEPGM 309

Query: 564 SMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLGPG 623
            +    GP+GP G           ++G P    +   +  P       +  +P     PG
Sbjct: 310 LVEGPPGPEGPAG-----------LIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPG 358

Query: 624 PIANG----FPPGGPGGPKG-------------------MQHFPPGPGG--PMPGPHGGP 658
           P        F  G  GG KG                       PPGP G    PGP G P
Sbjct: 359 PPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQP 418

Query: 659 G-----------GPVGPR----LLGPPPPP-RGGDPFWDG----PGDPMRGGPMRGGPGP 698
           G           GP GPR    L GPP    R G    DG    PGDP   G  RG  G 
Sbjct: 419 GSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGD-RGFDGL 477

Query: 699 GPGPYHRGRGGRGGNEPPPPPPPFRGARG--------GRSGGGPPNGRGGPGG--GMVGG 748
              P  +G  G  G +  P PP   G RG        G  G   P G  GP G  G+ G 
Sbjct: 478 PGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGP 537

Query: 749 GGHRPHEGPGGGMGNSSGHRPHEGPGGGMGS-GHRPHEGPGGSMGGGGGHRPHEGPG--- 804
            G R  +GP G  G S G +   GP G  G+ G +   GP G++G  G   P   PG   
Sbjct: 538 PGVRGMDGPQGPKG-SLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPG 596

Query: 805 -GGISGGSGHRPHEGPGGGMGAGGGHRP-----HEGPGGSMGGSG-----GHRPHEG--- 850
             G  G  GH   EGP G  G  G   P     + GP G  G  G     GH+  +G   
Sbjct: 597 MPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDG 656

Query: 851 -PGHGGPHGHRPH----DVPGHRGHDHRGPPPHEHRGHDGP 886
            PG  G  G +       VPG RG D     P   +G  GP
Sbjct: 657 FPGFKGDIGVKGDRGEVGVPGSRGED----GPEGPKGRTGP 693



 Score =  100 bits (249), Expect = 6e-21
 Identities = 121/373 (32%), Positives = 133/373 (35%), Gaps = 76/373 (20%)

Query: 539  PGGSGGSPDGAG--GSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHP 596
            P G  G     G  G   PP      G  GA  GPQGP GG  N+        G P    
Sbjct: 1077 PSGEKGETGDVGPMGPPGPPGPRGPAGPNGAD-GPQGPPGGVGNLGP--PGEKGEPGESG 1133

Query: 597  SEELLKQPDYSDKIKQMLVPHGLLGP----GPIANGFPPGGPGGPKGMQHFPPGPGGPM- 651
            S  +  +P             G+ GP    G       PG PG        PPGP GP  
Sbjct: 1134 SPGIQGEP-------------GVKGPRGERGEKGESGQPGEPG--------PPGPKGPTG 1172

Query: 652  -PGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPY-HRGRGG 709
              GP G PG PVG    G P PP  G P         RG     G    PGP    G  G
Sbjct: 1173 DDGPKGNPG-PVG--FPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPG 1229

Query: 710  RGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGG-GMVGGGGHRPHEGPGG--GMGNSSG 766
              G   P   P   G +GG+   G P   G PG  G VG  G     GP G  G+  S G
Sbjct: 1230 PLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG 1289

Query: 767  H--RP----HEGPGGGMG-------------SGHRPHEGPGGSMGGGG-----GHRPHEG 802
               RP      GP G +G              G + H G  G +G  G     G R   G
Sbjct: 1290 QQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1349

Query: 803  PGG--------GISGGSGHRPHEGPGGGMGAGG--GHRPHEGPGGSMGGSGGHRPHEGPG 852
            P G        GI G SG     GP G  G  G  G +   GPGG  G  G   P   PG
Sbjct: 1350 PQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGP---PG 1406

Query: 853  HGGPHGHRPHDVP 865
            H GP G     +P
Sbjct: 1407 HPGPPGEVIQPLP 1419



 Score = 98.6 bits (244), Expect = 2e-20
 Identities = 126/411 (30%), Positives = 148/411 (36%), Gaps = 62/411 (15%)

Query: 538  EPGGSGG-SPDGAGGSKLPPVLANLMGSMGA-----GKGPQGPGGGGINVQEILTSIMGS 591
            +PG  G    DG  G +  P    L G+ G       +GP GP G   +  E   +  G 
Sbjct: 882  DPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGG 941

Query: 592  PNSHPSEELLKQPDYSDKIKQMLVPHGLLGP-------GPIANGFPPGGPG--------- 635
            P   P     + P  +   K +    G +GP       GP+    P G PG         
Sbjct: 942  PIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 1001

Query: 636  -----GPKGM-----QHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGD 685
                 G KG      +H PPGP GP+     GP G  G       P  RG    +   GD
Sbjct: 1002 EVGDPGQKGTKGNKGEHGPPGPPGPI-----GPVGQPGAAGADGEPGARGPQGHFGAKGD 1056

Query: 686  PMRGGPMRGGPGPG-----PGPY-HRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRG 739
                G   G PGP      PGP   +G  G  G   PP PP  RG  G     GP   +G
Sbjct: 1057 EGTRG-FNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGP---QG 1112

Query: 740  GPGG-GMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMG----SGHRPHEGPGGSMGGG 794
             PGG G +G  G +   G  G  G   G    +GP G  G    SG     GP G  G  
Sbjct: 1113 PPGGVGNLGPPGEKGEPGESGSPG-IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1171

Query: 795  GGHRPHEGPGG-GISGGSGHRPHEGPGGGMGAGG--GHRPHEGPGGSMGGSGGHRPHEGP 851
            G   P   PG  G  G  G     GP G  GA G  G     G  GS G +G + P    
Sbjct: 1172 GDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPL 1231

Query: 852  GHGGPHGHRPHDVPGHRGHDHRGPP----PHEHRGHDGPGHGGGGHRGHDG 898
            G  GP G  P       G   +G P         G  GP  G  G  G DG
Sbjct: 1232 GKRGPAG-SPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPA-GPAGKPGPDG 1280



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 144/445 (32%), Positives = 159/445 (35%), Gaps = 99/445 (22%)

Query: 539 PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
           PG SG  P G  G K PP +    G  G   GPQGP G             G P   P +
Sbjct: 517 PGESG--PRGLLGPKGPPGIPGPPGVRGMD-GPQGPKGS--------LGPQGEPGP-PGQ 564

Query: 599 ELLKQPDYSDKIKQMLVPHGLLGP-------GPIANGFPPGGPG-----GPKGMQHFPPG 646
           +           +  + PHG  GP       G   +  PPG PG     G KG Q  P G
Sbjct: 565 QGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQG-PSG 623

Query: 647 PGGPM--PGPHGGPGGPVGPRLLGPPPPPRGGDPF-----------------------WD 681
           P GP+  PGP G  G   G R L      +G D F                        D
Sbjct: 624 PQGPLGYPGPRGVKGVD-GIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED 682

Query: 682 GPGDPM-RGGPMRGGPGPG-----------PG-PYHRGRGGRGGNEPPPPPPPF---RGA 725
           GP  P  R GP  G PGP            PG P + GR G  G+   P  P     +GA
Sbjct: 683 GPEGPKGRTGPT-GDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGA 741

Query: 726 RGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPG-----GGMG-S 779
           RG     G P G  GP G   G  G R   G  G  G S G  PH  PG     G  G +
Sbjct: 742 RGLSGKSG-PRGERGPTGPR-GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPN 799

Query: 780 GHRPHEGPGGSMGGGG--GHRPHEGPGG--GISGGSGHRPHEGPGGGMGAGG--GHRPHE 833
           G    +GP G  G  G  GH    G  G  G +G  G     GP G  G  G  G R H 
Sbjct: 800 GFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHP 859

Query: 834 GP------------GGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRG--HDHRGPPPHE 879
           GP             G  G  G   P   PG  GP G R    PG RG      GP    
Sbjct: 860 GPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLR--GFPGERGLPGTAGGPGLKG 917

Query: 880 HRGHDGPGHGGGGHRGHDGGHSHGG 904
           + G  GP  G  G  G  G    GG
Sbjct: 918 NEGPSGP-PGPAGSPGERGAAGSGG 941



 Score = 94.7 bits (234), Expect = 3e-19
 Identities = 134/415 (32%), Positives = 155/415 (37%), Gaps = 80/415 (19%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
            P G  G P GA G+   P      G  GA KG +G  G   N       + G P   PS 
Sbjct: 1026 PIGPVGQP-GAAGADGEPGARGPQGHFGA-KGDEGTRG--FNGPPGPIGLQGLPG--PSG 1079

Query: 599  ELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPG--GPMPGPHG 656
            E  +  D          P G  GP P   G  P GP G  G Q  P G G  GP PG  G
Sbjct: 1080 EKGETGDVG--------PMGPPGP-PGPRG--PAGPNGADGPQGPPGGVGNLGP-PGEKG 1127

Query: 657  GPGGPVGPRLLGPP--PPPRG-----------GDPFWDGPGDPMRGGPMRGGPGP----- 698
             PG    P + G P    PRG           G+P   GP  P      +G PGP     
Sbjct: 1128 EPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPG 1187

Query: 699  GPGPYH----RGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRG--GPGG-----GMVG 747
             PGP      RG+ G  G+      P   G+ G     GPP   G  GP G     G  G
Sbjct: 1188 DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQG 1247

Query: 748  GGGHRPHEGPGGGMGNS-----SGHRPHEGPGGGMG-SGHRPHEGPGGSMGGGGGHRPHE 801
            G G +   G  G  G +     +G     GP G  G  G    +G  G+ G  G   P  
Sbjct: 1248 GKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVG 1307

Query: 802  GPG----GGISGGSGHRPHEGPGGGMGAGG-----GHRPHEGPGGSMGGSG--GHRPHEG 850
             PG     G +G  G + H G  G +G  G     G R   GP GS G  G  G     G
Sbjct: 1308 PPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASG 1367

Query: 851  P-GHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDGGHSHGG 904
            P G GGP G     +PG  G       P   +G  GPG G  G +G  G   H G
Sbjct: 1368 PIGPGGPPG-----LPGPAG-------PKGAKGATGPG-GPKGEKGVQGPPGHPG 1409



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 73/255 (28%), Positives = 90/255 (35%), Gaps = 51/255 (20%)

Query: 464  PRPLVLPSPLVTPGSNSQERYIQAEREKGILQELFLNKESPHEPDPEPYEPIPPKLIPLD 523
            P PL    P  +PGS  ++    A+ + G +      K  P  P     +P P  L  L 
Sbjct: 1228 PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAP--GKTGPVGPAGPAGKPGPDGLRGLP 1285

Query: 524  EECSMDETPYVETLEPGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQE 583
                    P        G  G P   G    PP L  L G  GA KG +G  G       
Sbjct: 1286 GSVGQQGRPGAT-----GQAGPPGPVG----PPGLPGLRGDAGA-KGEKGHPG------- 1328

Query: 584  ILTSIMGSPNSH--PSEELLKQPDYSDKIK-QMLVPHGLLGPGPIANGFPPG-------- 632
             L  ++G P       +  L  P  S   K +M +P      GPI  G PPG        
Sbjct: 1329 -LIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGA---SGPIGPGGPPGLPGPAGPK 1384

Query: 633  ------GPGGPKGMQHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPR----GGDPFWDG 682
                  GPGGPKG +    G  GP PG  G PG  + P  +  P   R    G     + 
Sbjct: 1385 GAKGATGPGGPKGEK----GVQGP-PGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQED 1439

Query: 683  PGDPMRGGPMRGGPG 697
               P  G P  G PG
Sbjct: 1440 EAIPTGGAP--GSPG 1452


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score =  118 bits (296), Expect = 2e-26
 Identities = 159/499 (31%), Positives = 183/499 (36%), Gaps = 98/499 (19%)

Query: 513  EPIPPKLIPLDEECSMDETP-YVETLEPGGSGGSPD--GAGGSKLPPVLANLMGSMGAGK 569
            +P PP L+    +  +   P Y     P GS G P   GA G K    L+   G  G  +
Sbjct: 675  DPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGE-R 733

Query: 570  GPQGPGGGGINVQEILTSIMGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLG----PGPI 625
            GP GP G               P     +   K     D       PHG  G    PGP 
Sbjct: 734  GPTGPRG------------QRGPRGATGKSGAKGTSGGDG------PHGPPGERGLPGPQ 775

Query: 626  A-NGFP-PGGPGGPKGMQHFPPGPG-----------GPMPGPHG--------GPGGPVGP 664
              NGFP P GP GP G    P  PG           GP PGP G        G  GP+G 
Sbjct: 776  GPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGP-PGPPGVVGPQGAAGETGPMGE 834

Query: 665  R-LLGPPPPP-------------RGGDPFWDGPGDPMRGGP--MRGGPGPGPGPYHRGRG 708
            R   GPP PP               GDP    PG P + GP  +RG PG    P   G  
Sbjct: 835  RGHPGPPGPPGEQGLPGTAGKEGTKGDP--GPPGAPGKDGPAGLRGFPGERGLPGTAGGP 892

Query: 709  GRGGNEPPPPPPPFRGA---RGGRSGGGP--PNGRGGPGG--GMVGGGGHRPHEGPGGGM 761
            G  GNE P  PP   G+   RG    GGP  P GR GP G  G  G  G    +GP G  
Sbjct: 893  GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPT 952

Query: 762  GNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGG-----GHRPHEGPGG----------- 805
            G      P   PG     G    +G  G +G  G     G++   GP G           
Sbjct: 953  GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQP 1012

Query: 806  GISGGSGHRPHEGPGGGMGAGG--GHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHD 863
            G +G  G     GP G  GA G  G R   GP G +G  G   P    G  G  G  P  
Sbjct: 1013 GAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVG--PMG 1070

Query: 864  VPGHRGHDHRGPP-PHEHRGHDGPGHGGGGHRGHDGGHSHGGDMSNRPVCRHFMMKG-NC 921
             PG  G   RGP  P+   G  GP  GG G+ G  G     G+  +  +     +KG   
Sbjct: 1071 PPGPPG--PRGPAGPNGADGPQGP-PGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG 1127

Query: 922  RYENNCAFYHPGVNGPPLP 940
                      PG  GPP P
Sbjct: 1128 ERGEKGESGQPGEPGPPGP 1146



 Score =  100 bits (249), Expect = 6e-21
 Identities = 121/373 (32%), Positives = 133/373 (35%), Gaps = 76/373 (20%)

Query: 539  PGGSGGSPDGAG--GSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHP 596
            P G  G     G  G   PP      G  GA  GPQGP GG  N+        G P    
Sbjct: 1056 PSGEKGETGDVGPMGPPGPPGPRGPAGPNGAD-GPQGPPGGVGNLGP--PGEKGEPGESG 1112

Query: 597  SEELLKQPDYSDKIKQMLVPHGLLGP----GPIANGFPPGGPGGPKGMQHFPPGPGGPM- 651
            S  +  +P             G+ GP    G       PG PG        PPGP GP  
Sbjct: 1113 SPGIQGEP-------------GVKGPRGERGEKGESGQPGEPG--------PPGPKGPTG 1151

Query: 652  -PGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPY-HRGRGG 709
              GP G PG PVG    G P PP  G P         RG     G    PGP    G  G
Sbjct: 1152 DDGPKGNPG-PVG--FPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPG 1208

Query: 710  RGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGG-GMVGGGGHRPHEGPGG--GMGNSSG 766
              G   P   P   G +GG+   G P   G PG  G VG  G     GP G  G+  S G
Sbjct: 1209 PLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG 1268

Query: 767  H--RP----HEGPGGGMG-------------SGHRPHEGPGGSMGGGG-----GHRPHEG 802
               RP      GP G +G              G + H G  G +G  G     G R   G
Sbjct: 1269 QQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1328

Query: 803  PGG--------GISGGSGHRPHEGPGGGMGAGG--GHRPHEGPGGSMGGSGGHRPHEGPG 852
            P G        GI G SG     GP G  G  G  G +   GPGG  G  G   P   PG
Sbjct: 1329 PQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGP---PG 1385

Query: 853  HGGPHGHRPHDVP 865
            H GP G     +P
Sbjct: 1386 HPGPPGEVIQPLP 1398



 Score =  100 bits (248), Expect = 8e-21
 Identities = 130/392 (33%), Positives = 155/392 (39%), Gaps = 68/392 (17%)

Query: 539 PGGSGGSPDGAG--GSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHP 596
           P G  G+P   G  G + PP  A L GS GA      PG  G ++  +L    GS     
Sbjct: 305 PPGIQGNPGPVGDPGERGPPGRAGLPGSDGA------PGPPGTSL--MLPFRFGSGGGDK 356

Query: 597 SEELLKQPDYSDKIKQM--LVPHGLLGP-GPIANGFPPGGPGGPKGMQHFPPGPGGPMPG 653
              +  Q   +  I Q   L   G  GP G      P G PG P G++    G  G +  
Sbjct: 357 GPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSP-GLK----GESGDL-- 409

Query: 654 PHGGPGGPVGPRLLGPPPPPRG--GDPFWDG----PGDPMRGGPMRGGPGPGPGPYHRGR 707
              GP GP GP+ L  PP   G  G    DG    PGDP   G  RG  G    P  +G 
Sbjct: 410 ---GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGD-RGFDGLPGLPGEKGH 465

Query: 708 GGRGGNEPPPPPPPFRGARG--------GRSGGGPPNGRGGPGG--GMVGGGGHRPHEGP 757
            G  G +  P PP   G RG        G  G   P G  GP G  G+ G  G R  +GP
Sbjct: 466 RGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGP 525

Query: 758 GGGMGNSSGHRPHEGPGGGMGS-GHRPHEGPGGSMGGGGGHRPHEGPG----GGISGGSG 812
            G  G S G +   GP G  G+ G +   GP G++G  G   P   PG     G  G  G
Sbjct: 526 QGPKG-SLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPG 584

Query: 813 HRPHEGPGGGMGAGGGHRP-----HEGPGGSMGGSG-----GHRPHEG----PGHGGPHG 858
           H   EGP G  G  G   P     + GP G  G  G     GH+  +G    PG  G  G
Sbjct: 585 HPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIG 644

Query: 859 HRPH----DVPGHRGHDHRGPPPHEHRGHDGP 886
            +       VPG RG D     P   +G  GP
Sbjct: 645 VKGDRGEVGVPGSRGED----GPEGPKGRTGP 672



 Score = 98.6 bits (244), Expect = 2e-20
 Identities = 126/411 (30%), Positives = 148/411 (36%), Gaps = 62/411 (15%)

Query: 538  EPGGSGG-SPDGAGGSKLPPVLANLMGSMGA-----GKGPQGPGGGGINVQEILTSIMGS 591
            +PG  G    DG  G +  P    L G+ G       +GP GP G   +  E   +  G 
Sbjct: 861  DPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGG 920

Query: 592  PNSHPSEELLKQPDYSDKIKQMLVPHGLLGP-------GPIANGFPPGGPG--------- 635
            P   P     + P  +   K +    G +GP       GP+    P G PG         
Sbjct: 921  PIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 980

Query: 636  -----GPKGM-----QHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGD 685
                 G KG      +H PPGP GP+     GP G  G       P  RG    +   GD
Sbjct: 981  EVGDPGQKGTKGNKGEHGPPGPPGPI-----GPVGQPGAAGADGEPGARGPQGHFGAKGD 1035

Query: 686  PMRGGPMRGGPGPG-----PGPY-HRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRG 739
                G   G PGP      PGP   +G  G  G   PP PP  RG  G     GP   +G
Sbjct: 1036 EGTRG-FNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGP---QG 1091

Query: 740  GPGG-GMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMG----SGHRPHEGPGGSMGGG 794
             PGG G +G  G +   G  G  G   G    +GP G  G    SG     GP G  G  
Sbjct: 1092 PPGGVGNLGPPGEKGEPGESGSPG-IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1150

Query: 795  GGHRPHEGPGG-GISGGSGHRPHEGPGGGMGAGG--GHRPHEGPGGSMGGSGGHRPHEGP 851
            G   P   PG  G  G  G     GP G  GA G  G     G  GS G +G + P    
Sbjct: 1151 GDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPL 1210

Query: 852  GHGGPHGHRPHDVPGHRGHDHRGPP----PHEHRGHDGPGHGGGGHRGHDG 898
            G  GP G  P       G   +G P         G  GP  G  G  G DG
Sbjct: 1211 GKRGPAG-SPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPA-GPAGKPGPDG 1259



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 144/445 (32%), Positives = 159/445 (35%), Gaps = 99/445 (22%)

Query: 539 PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
           PG SG  P G  G K PP +    G  G   GPQGP G             G P   P +
Sbjct: 496 PGESG--PRGLLGPKGPPGIPGPPGVRGMD-GPQGPKGS--------LGPQGEPGP-PGQ 543

Query: 599 ELLKQPDYSDKIKQMLVPHGLLGP-------GPIANGFPPGGPG-----GPKGMQHFPPG 646
           +           +  + PHG  GP       G   +  PPG PG     G KG Q  P G
Sbjct: 544 QGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQG-PSG 602

Query: 647 PGGPM--PGPHGGPGGPVGPRLLGPPPPPRGGDPF-----------------------WD 681
           P GP+  PGP G  G   G R L      +G D F                        D
Sbjct: 603 PQGPLGYPGPRGVKGVD-GIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED 661

Query: 682 GPGDPM-RGGPMRGGPGPG-----------PG-PYHRGRGGRGGNEPPPPPPPF---RGA 725
           GP  P  R GP  G PGP            PG P + GR G  G+   P  P     +GA
Sbjct: 662 GPEGPKGRTGPT-GDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGA 720

Query: 726 RGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPG-----GGMG-S 779
           RG     G P G  GP G   G  G R   G  G  G S G  PH  PG     G  G +
Sbjct: 721 RGLSGKSG-PRGERGPTGPR-GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPN 778

Query: 780 GHRPHEGPGGSMGGGG--GHRPHEGPGG--GISGGSGHRPHEGPGGGMGAGG--GHRPHE 833
           G    +GP G  G  G  GH    G  G  G +G  G     GP G  G  G  G R H 
Sbjct: 779 GFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHP 838

Query: 834 GP------------GGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRG--HDHRGPPPHE 879
           GP             G  G  G   P   PG  GP G R    PG RG      GP    
Sbjct: 839 GPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLR--GFPGERGLPGTAGGPGLKG 896

Query: 880 HRGHDGPGHGGGGHRGHDGGHSHGG 904
           + G  GP  G  G  G  G    GG
Sbjct: 897 NEGPSGP-PGPAGSPGERGAAGSGG 920



 Score = 94.7 bits (234), Expect = 3e-19
 Identities = 134/415 (32%), Positives = 155/415 (37%), Gaps = 80/415 (19%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
            P G  G P GA G+   P      G  GA KG +G  G   N       + G P   PS 
Sbjct: 1005 PIGPVGQP-GAAGADGEPGARGPQGHFGA-KGDEGTRG--FNGPPGPIGLQGLPG--PSG 1058

Query: 599  ELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPG--GPMPGPHG 656
            E  +  D          P G  GP P   G  P GP G  G Q  P G G  GP PG  G
Sbjct: 1059 EKGETGDVG--------PMGPPGP-PGPRG--PAGPNGADGPQGPPGGVGNLGP-PGEKG 1106

Query: 657  GPGGPVGPRLLGPP--PPPRG-----------GDPFWDGPGDPMRGGPMRGGPGP----- 698
             PG    P + G P    PRG           G+P   GP  P      +G PGP     
Sbjct: 1107 EPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPG 1166

Query: 699  GPGPYH----RGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRG--GPGG-----GMVG 747
             PGP      RG+ G  G+      P   G+ G     GPP   G  GP G     G  G
Sbjct: 1167 DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQG 1226

Query: 748  GGGHRPHEGPGGGMGNS-----SGHRPHEGPGGGMG-SGHRPHEGPGGSMGGGGGHRPHE 801
            G G +   G  G  G +     +G     GP G  G  G    +G  G+ G  G   P  
Sbjct: 1227 GKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVG 1286

Query: 802  GPG----GGISGGSGHRPHEGPGGGMGAGG-----GHRPHEGPGGSMGGSG--GHRPHEG 850
             PG     G +G  G + H G  G +G  G     G R   GP GS G  G  G     G
Sbjct: 1287 PPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASG 1346

Query: 851  P-GHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDGGHSHGG 904
            P G GGP G     +PG  G       P   +G  GPG G  G +G  G   H G
Sbjct: 1347 PIGPGGPPG-----LPGPAG-------PKGAKGATGPG-GPKGEKGVQGPPGHPG 1388



 Score = 92.0 bits (227), Expect = 2e-18
 Identities = 120/371 (32%), Positives = 137/371 (36%), Gaps = 78/371 (21%)

Query: 591 SPNSHPSEELLKQPDYSDKIKQMLV-PHGLLG---------PGPIANGFPPGGPGGPKGM 640
           SP   PS   L +P   +   Q    P GL G         PG +  G  P GP GP G+
Sbjct: 247 SPQQQPSR--LHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEG--PPGPEGPAGL 302

Query: 641 QHFPPGPGGPMPGPHGGPG--GPVG----PRLLGPPPPPRGG--DPFWDGPGDPMRGG-- 690
              PPG  G  PGP G PG  GP G    P   G P PP      PF  G G   +G   
Sbjct: 303 IG-PPGIQG-NPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVV 360

Query: 691 ----------------PMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGP 734
                            +RG PGP       G  GR G    P  P  +G  G     GP
Sbjct: 361 AAQEAQAQAILQQARLALRGPPGP------MGYTGRPGPLGQPGSPGLKGESGDLGPQGP 414

Query: 735 --PNGRGGPGG-----GMVGGGGHRPHEGPGG--------GMGNSSGHRPHEGPGGGMG- 778
             P G  GP G     G  G  G R   G  G        G+    G + H G  G  G 
Sbjct: 415 RGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGL 474

Query: 779 ------SGHRPHEGPGGSMG--GGGGHRPHEGPGG--GISGGSGHRPHEGPGGGMGAGGG 828
                  G R  +G  G  G  G  G R   GP G  GI G  G R  +GP G  G+  G
Sbjct: 475 PGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGS-LG 533

Query: 829 HRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHR-PHDVPGHRGHDHRGPPPHEHRGHDGPG 887
            +   GP G  G  G        G  GPHG + P   PG  G      PP  H G +GP 
Sbjct: 534 PQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPP-GHPGKEGP- 591

Query: 888 HGGGGHRGHDG 898
            G  G++G  G
Sbjct: 592 PGTKGNQGPSG 602



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 73/255 (28%), Positives = 90/255 (35%), Gaps = 51/255 (20%)

Query: 464  PRPLVLPSPLVTPGSNSQERYIQAEREKGILQELFLNKESPHEPDPEPYEPIPPKLIPLD 523
            P PL    P  +PGS  ++    A+ + G +      K  P  P     +P P  L  L 
Sbjct: 1207 PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAP--GKTGPVGPAGPAGKPGPDGLRGLP 1264

Query: 524  EECSMDETPYVETLEPGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQE 583
                    P        G  G P   G    PP L  L G  GA KG +G  G       
Sbjct: 1265 GSVGQQGRPGAT-----GQAGPPGPVG----PPGLPGLRGDAGA-KGEKGHPG------- 1307

Query: 584  ILTSIMGSPNSH--PSEELLKQPDYSDKIK-QMLVPHGLLGPGPIANGFPPG-------- 632
             L  ++G P       +  L  P  S   K +M +P      GPI  G PPG        
Sbjct: 1308 -LIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGA---SGPIGPGGPPGLPGPAGPK 1363

Query: 633  ------GPGGPKGMQHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPR----GGDPFWDG 682
                  GPGGPKG +    G  GP PG  G PG  + P  +  P   R    G     + 
Sbjct: 1364 GAKGATGPGGPKGEK----GVQGP-PGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQED 1418

Query: 683  PGDPMRGGPMRGGPG 697
               P  G P  G PG
Sbjct: 1419 EAIPTGGAP--GSPG 1431


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score =  118 bits (296), Expect = 2e-26
 Identities = 159/499 (31%), Positives = 183/499 (36%), Gaps = 98/499 (19%)

Query: 513  EPIPPKLIPLDEECSMDETP-YVETLEPGGSGGSPD--GAGGSKLPPVLANLMGSMGAGK 569
            +P PP L+    +  +   P Y     P GS G P   GA G K    L+   G  G  +
Sbjct: 782  DPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGE-R 840

Query: 570  GPQGPGGGGINVQEILTSIMGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLG----PGPI 625
            GP GP G               P     +   K     D       PHG  G    PGP 
Sbjct: 841  GPTGPRG------------QRGPRGATGKSGAKGTSGGDG------PHGPPGERGLPGPQ 882

Query: 626  A-NGFP-PGGPGGPKGMQHFPPGPG-----------GPMPGPHG--------GPGGPVGP 664
              NGFP P GP GP G    P  PG           GP PGP G        G  GP+G 
Sbjct: 883  GPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGP-PGPPGVVGPQGAAGETGPMGE 941

Query: 665  R-LLGPPPPP-------------RGGDPFWDGPGDPMRGGP--MRGGPGPGPGPYHRGRG 708
            R   GPP PP               GDP    PG P + GP  +RG PG    P   G  
Sbjct: 942  RGHPGPPGPPGEQGLPGTAGKEGTKGDP--GPPGAPGKDGPAGLRGFPGERGLPGTAGGP 999

Query: 709  GRGGNEPPPPPPPFRGA---RGGRSGGGP--PNGRGGPGG--GMVGGGGHRPHEGPGGGM 761
            G  GNE P  PP   G+   RG    GGP  P GR GP G  G  G  G    +GP G  
Sbjct: 1000 GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPT 1059

Query: 762  GNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGG-----GHRPHEGPGG----------- 805
            G      P   PG     G    +G  G +G  G     G++   GP G           
Sbjct: 1060 GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQP 1119

Query: 806  GISGGSGHRPHEGPGGGMGAGG--GHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHD 863
            G +G  G     GP G  GA G  G R   GP G +G  G   P    G  G  G  P  
Sbjct: 1120 GAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVG--PMG 1177

Query: 864  VPGHRGHDHRGPP-PHEHRGHDGPGHGGGGHRGHDGGHSHGGDMSNRPVCRHFMMKG-NC 921
             PG  G   RGP  P+   G  GP  GG G+ G  G     G+  +  +     +KG   
Sbjct: 1178 PPGPPG--PRGPAGPNGADGPQGP-PGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG 1234

Query: 922  RYENNCAFYHPGVNGPPLP 940
                      PG  GPP P
Sbjct: 1235 ERGEKGESGQPGEPGPPGP 1253



 Score =  101 bits (252), Expect = 3e-21
 Identities = 133/441 (30%), Positives = 158/441 (35%), Gaps = 95/441 (21%)

Query: 524 EECSMDETPYVETLEPGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQE 583
           EE  +      ET   G +   P G  G K  P +      +    GP+GP G       
Sbjct: 356 EETELGPALSAETAHSGAAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAG------- 408

Query: 584 ILTSIMGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANG----FPPGGPGGPKG 639
               ++G P    +   +  P       +  +P     PGP        F  G  GG KG
Sbjct: 409 ----LIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKG 464

Query: 640 -------------------MQHFPPGPGG--PMPGPHGGPG-----------GPVGPR-- 665
                                  PPGP G    PGP G PG           GP GPR  
Sbjct: 465 PVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGP 524

Query: 666 --LLGPPPPP-RGGDPFWDG----PGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPP 718
             L GPP    R G    DG    PGDP   G  RG  G    P  +G  G  G +  P 
Sbjct: 525 QGLTGPPGKAGRRGRAGADGARGMPGDPGVKGD-RGFDGLPGLPGEKGHRGDTGAQGLPG 583

Query: 719 PPPFRGARG--------GRSGGGPPNGRGGPGG--GMVGGGGHRPHEGPGGGMGNSSGHR 768
           PP   G RG        G  G   P G  GP G  G+ G  G R  +GP G  G S G +
Sbjct: 584 PPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKG-SLGPQ 642

Query: 769 PHEGPGGGMGS-GHRPHEGPGGSMGGGGGHRPHEGPG----GGISGGSGHRPHEGPGGGM 823
              GP G  G+ G +   GP G++G  G   P   PG     G  G  GH   EGP G  
Sbjct: 643 GEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTK 702

Query: 824 GAGGGHRP-----HEGPGGSMGGSG-----GHRPHEG----PGHGGPHGHRPH----DVP 865
           G  G   P     + GP G  G  G     GH+  +G    PG  G  G +       VP
Sbjct: 703 GNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVP 762

Query: 866 GHRGHDHRGPPPHEHRGHDGP 886
           G RG D     P   +G  GP
Sbjct: 763 GSRGED----GPEGPKGRTGP 779



 Score =  100 bits (249), Expect = 6e-21
 Identities = 121/373 (32%), Positives = 133/373 (35%), Gaps = 76/373 (20%)

Query: 539  PGGSGGSPDGAG--GSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHP 596
            P G  G     G  G   PP      G  GA  GPQGP GG  N+        G P    
Sbjct: 1163 PSGEKGETGDVGPMGPPGPPGPRGPAGPNGAD-GPQGPPGGVGNLGP--PGEKGEPGESG 1219

Query: 597  SEELLKQPDYSDKIKQMLVPHGLLGP----GPIANGFPPGGPGGPKGMQHFPPGPGGPM- 651
            S  +  +P             G+ GP    G       PG PG        PPGP GP  
Sbjct: 1220 SPGIQGEP-------------GVKGPRGERGEKGESGQPGEPG--------PPGPKGPTG 1258

Query: 652  -PGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPY-HRGRGG 709
              GP G PG PVG    G P PP  G P         RG     G    PGP    G  G
Sbjct: 1259 DDGPKGNPG-PVG--FPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPG 1315

Query: 710  RGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGG-GMVGGGGHRPHEGPGG--GMGNSSG 766
              G   P   P   G +GG+   G P   G PG  G VG  G     GP G  G+  S G
Sbjct: 1316 PLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG 1375

Query: 767  H--RP----HEGPGGGMG-------------SGHRPHEGPGGSMGGGG-----GHRPHEG 802
               RP      GP G +G              G + H G  G +G  G     G R   G
Sbjct: 1376 QQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1435

Query: 803  PGG--------GISGGSGHRPHEGPGGGMGAGG--GHRPHEGPGGSMGGSGGHRPHEGPG 852
            P G        GI G SG     GP G  G  G  G +   GPGG  G  G   P   PG
Sbjct: 1436 PQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGP---PG 1492

Query: 853  HGGPHGHRPHDVP 865
            H GP G     +P
Sbjct: 1493 HPGPPGEVIQPLP 1505



 Score = 98.6 bits (244), Expect = 2e-20
 Identities = 126/411 (30%), Positives = 148/411 (36%), Gaps = 62/411 (15%)

Query: 538  EPGGSGG-SPDGAGGSKLPPVLANLMGSMGA-----GKGPQGPGGGGINVQEILTSIMGS 591
            +PG  G    DG  G +  P    L G+ G       +GP GP G   +  E   +  G 
Sbjct: 968  DPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGG 1027

Query: 592  PNSHPSEELLKQPDYSDKIKQMLVPHGLLGP-------GPIANGFPPGGPG--------- 635
            P   P     + P  +   K +    G +GP       GP+    P G PG         
Sbjct: 1028 PIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 1087

Query: 636  -----GPKGM-----QHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGD 685
                 G KG      +H PPGP GP+     GP G  G       P  RG    +   GD
Sbjct: 1088 EVGDPGQKGTKGNKGEHGPPGPPGPI-----GPVGQPGAAGADGEPGARGPQGHFGAKGD 1142

Query: 686  PMRGGPMRGGPGPG-----PGPY-HRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRG 739
                G   G PGP      PGP   +G  G  G   PP PP  RG  G     GP   +G
Sbjct: 1143 EGTRG-FNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGP---QG 1198

Query: 740  GPGG-GMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMG----SGHRPHEGPGGSMGGG 794
             PGG G +G  G +   G  G  G   G    +GP G  G    SG     GP G  G  
Sbjct: 1199 PPGGVGNLGPPGEKGEPGESGSPG-IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1257

Query: 795  GGHRPHEGPGG-GISGGSGHRPHEGPGGGMGAGG--GHRPHEGPGGSMGGSGGHRPHEGP 851
            G   P   PG  G  G  G     GP G  GA G  G     G  GS G +G + P    
Sbjct: 1258 GDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPL 1317

Query: 852  GHGGPHGHRPHDVPGHRGHDHRGPP----PHEHRGHDGPGHGGGGHRGHDG 898
            G  GP G  P       G   +G P         G  GP  G  G  G DG
Sbjct: 1318 GKRGPAG-SPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPA-GPAGKPGPDG 1366



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 144/445 (32%), Positives = 159/445 (35%), Gaps = 99/445 (22%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
            PG SG  P G  G K PP +    G  G   GPQGP G             G P   P +
Sbjct: 603  PGESG--PRGLLGPKGPPGIPGPPGVRGMD-GPQGPKGS--------LGPQGEPGP-PGQ 650

Query: 599  ELLKQPDYSDKIKQMLVPHGLLGP-------GPIANGFPPGGPG-----GPKGMQHFPPG 646
            +           +  + PHG  GP       G   +  PPG PG     G KG Q  P G
Sbjct: 651  QGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQG-PSG 709

Query: 647  PGGPM--PGPHGGPGGPVGPRLLGPPPPPRGGDPF-----------------------WD 681
            P GP+  PGP G  G   G R L      +G D F                        D
Sbjct: 710  PQGPLGYPGPRGVKGVD-GIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED 768

Query: 682  GPGDPM-RGGPMRGGPGPG-----------PG-PYHRGRGGRGGNEPPPPPPPF---RGA 725
            GP  P  R GP  G PGP            PG P + GR G  G+   P  P     +GA
Sbjct: 769  GPEGPKGRTGPT-GDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGA 827

Query: 726  RGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPG-----GGMG-S 779
            RG     G P G  GP G   G  G R   G  G  G S G  PH  PG     G  G +
Sbjct: 828  RGLSGKSG-PRGERGPTGPR-GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPN 885

Query: 780  GHRPHEGPGGSMGGGG--GHRPHEGPGG--GISGGSGHRPHEGPGGGMGAGG--GHRPHE 833
            G    +GP G  G  G  GH    G  G  G +G  G     GP G  G  G  G R H 
Sbjct: 886  GFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHP 945

Query: 834  GP------------GGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRG--HDHRGPPPHE 879
            GP             G  G  G   P   PG  GP G R    PG RG      GP    
Sbjct: 946  GPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLR--GFPGERGLPGTAGGPGLKG 1003

Query: 880  HRGHDGPGHGGGGHRGHDGGHSHGG 904
            + G  GP  G  G  G  G    GG
Sbjct: 1004 NEGPSGP-PGPAGSPGERGAAGSGG 1027



 Score = 94.7 bits (234), Expect = 3e-19
 Identities = 134/415 (32%), Positives = 155/415 (37%), Gaps = 80/415 (19%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
            P G  G P GA G+   P      G  GA KG +G  G   N       + G P   PS 
Sbjct: 1112 PIGPVGQP-GAAGADGEPGARGPQGHFGA-KGDEGTRG--FNGPPGPIGLQGLPG--PSG 1165

Query: 599  ELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPG--GPMPGPHG 656
            E  +  D          P G  GP P   G  P GP G  G Q  P G G  GP PG  G
Sbjct: 1166 EKGETGDVG--------PMGPPGP-PGPRG--PAGPNGADGPQGPPGGVGNLGP-PGEKG 1213

Query: 657  GPGGPVGPRLLGPP--PPPRG-----------GDPFWDGPGDPMRGGPMRGGPGP----- 698
             PG    P + G P    PRG           G+P   GP  P      +G PGP     
Sbjct: 1214 EPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPG 1273

Query: 699  GPGPYH----RGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRG--GPGG-----GMVG 747
             PGP      RG+ G  G+      P   G+ G     GPP   G  GP G     G  G
Sbjct: 1274 DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQG 1333

Query: 748  GGGHRPHEGPGGGMGNS-----SGHRPHEGPGGGMG-SGHRPHEGPGGSMGGGGGHRPHE 801
            G G +   G  G  G +     +G     GP G  G  G    +G  G+ G  G   P  
Sbjct: 1334 GKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVG 1393

Query: 802  GPG----GGISGGSGHRPHEGPGGGMGAGG-----GHRPHEGPGGSMGGSG--GHRPHEG 850
             PG     G +G  G + H G  G +G  G     G R   GP GS G  G  G     G
Sbjct: 1394 PPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASG 1453

Query: 851  P-GHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDGGHSHGG 904
            P G GGP G     +PG  G       P   +G  GPG G  G +G  G   H G
Sbjct: 1454 PIGPGGPPG-----LPGPAG-------PKGAKGATGPG-GPKGEKGVQGPPGHPG 1495



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 73/255 (28%), Positives = 90/255 (35%), Gaps = 51/255 (20%)

Query: 464  PRPLVLPSPLVTPGSNSQERYIQAEREKGILQELFLNKESPHEPDPEPYEPIPPKLIPLD 523
            P PL    P  +PGS  ++    A+ + G +      K  P  P     +P P  L  L 
Sbjct: 1314 PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAP--GKTGPVGPAGPAGKPGPDGLRGLP 1371

Query: 524  EECSMDETPYVETLEPGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQE 583
                    P        G  G P   G    PP L  L G  GA KG +G  G       
Sbjct: 1372 GSVGQQGRPGAT-----GQAGPPGPVG----PPGLPGLRGDAGA-KGEKGHPG------- 1414

Query: 584  ILTSIMGSPNSH--PSEELLKQPDYSDKIK-QMLVPHGLLGPGPIANGFPPG-------- 632
             L  ++G P       +  L  P  S   K +M +P      GPI  G PPG        
Sbjct: 1415 -LIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGA---SGPIGPGGPPGLPGPAGPK 1470

Query: 633  ------GPGGPKGMQHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPR----GGDPFWDG 682
                  GPGGPKG +    G  GP PG  G PG  + P  +  P   R    G     + 
Sbjct: 1471 GAKGATGPGGPKGEK----GVQGP-PGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQED 1525

Query: 683  PGDPMRGGPMRGGPG 697
               P  G P  G PG
Sbjct: 1526 EAIPTGGAP--GSPG 1538


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score =  117 bits (293), Expect = 5e-26
 Identities = 126/369 (34%), Positives = 147/369 (39%), Gaps = 63/369 (17%)

Query: 568 GKGPQGPGGGGIN----------VQEILTSIMGSPNSHPSEELLKQPDYSDKIKQMLVPH 617
           G GP+   GGG            +Q +    +G P      + L+ P         L+P 
Sbjct: 21  GCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMP-------LPLLPM 73

Query: 618 GLLG-PGPIANGFPPGGPG--GPKGMQHFPPGPGGPMPGPHG--GPGGPVGPRLLGPPPP 672
            L G PGP      PG PG  GP G   FP  PG   PG HG  GP GP G   +G   P
Sbjct: 74  DLKGEPGP------PGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGP 127

Query: 673 PRGGDPFWDGP-GDP-MRGGP-------MRGGPGPG--PGPYHRGRGGRGGNEPPPPPPP 721
           P  G P   GP G P +RG P       +RG PGP   PGP      G+ G +  P PP 
Sbjct: 128 P--GLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPG 185

Query: 722 FRGARGGRSGGGPPNGRGGPGGGMVG----------GGGHRPHEGPG-GGMGNSSGHRPH 770
           F+G  G +   GPP  RG  G   VG          GG   P   PG  G+G        
Sbjct: 186 FQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLP 245

Query: 771 EGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHR 830
             PG    SG     GP G  G  G   P    G G+ G +G    +GP G  G  G   
Sbjct: 246 GAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPG--- 302

Query: 831 PHEGPGGSMGGSGGHRPHEGPGHGGPHGHR-PHDVPGHRGHDHRGPPPHEHRGHDGPGHG 889
              GP G +G +G    +  PG  GP G R P  VPG  G D   P      G  GP  G
Sbjct: 303 -TRGPPGLIGPTG----YGMPGLPGPKGDRGPAGVPGLLG-DRGEPGEDGEPGEQGP-QG 355

Query: 890 GGGHRGHDG 898
            GG  G  G
Sbjct: 356 LGGPPGLPG 364



 Score = 94.4 bits (233), Expect = 5e-19
 Identities = 123/378 (32%), Positives = 143/378 (37%), Gaps = 63/378 (16%)

Query: 539 PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEIL--TSIMGSPNSHP 596
           PG SG +  G  G++  P      G  G    P  PG  G+     +    + G+P    
Sbjct: 164 PGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGG 223

Query: 597 SEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFP-----PGGPGGPKGMQHFPPGPGGPM 651
           +                  P GL  PGP   G P     PG P G KG +  PPG    +
Sbjct: 224 APG----------------PPGL--PGPAGLGKPGLDGLPGAP-GDKG-ESGPPG----V 259

Query: 652 PGPHGGPGGPVGPRLLGPP------PPPRGGDPFWDGPGDPMRGGPMRGGPG-PGPGPYH 704
           PGP G PG  VGP+  GPP       P   G P   GP         RG PG  GP  Y 
Sbjct: 260 PGPRGEPGA-VGPK--GPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYG 316

Query: 705 R-GRGGRGGNEPPPPPPPFRGARG-----GRSGGGPPNGRGGPGGGMVGGGGHRPHEGPG 758
             G  G  G+  P   P   G RG     G  G   P G GGP  G+ G  G     GP 
Sbjct: 317 MPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGP-PGLPGSAGLPGRRGPP 375

Query: 759 GGMGNSSGHRPHEGPGGGMG-SGHRPHEGPGGSMGGGG--GHRPHEGPGG--GISGGSGH 813
           G  G +       GPGG  G  G R  +GP G  G  G  G R   G  G  G +G  G 
Sbjct: 376 GPKGEA-------GPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGE 428

Query: 814 RPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGH-RPHDVPGHRGHDH 872
               G  GG G  G     +G  G  G  G   P   PG  GP G   P  +PG +G   
Sbjct: 429 PGFTGRPGGPGVAGA-LGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPG 487

Query: 873 RGPPPHEHRGHDGPGHGG 890
              PP E R  + PG  G
Sbjct: 488 LPGPPGEGRAGE-PGTAG 504



 Score = 90.5 bits (223), Expect = 7e-18
 Identities = 127/403 (31%), Positives = 149/403 (36%), Gaps = 70/403 (17%)

Query: 506 EPDPEPYEPIPPKLIPLDEECSMDETPYVETLEPGGSGGSPDGAGGSKL-PPVLANLMGS 564
           EP P+  EP PP    L  +  + +         GG+ G P   G + L  P L  L G+
Sbjct: 189 EPGPQG-EPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGA 247

Query: 565 MGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLGPGP 624
            G  KG  GP G            +  P   P     K P   D +    VP     PGP
Sbjct: 248 PG-DKGESGPPG------------VPGPRGEPGAVGPKGPPGVDGVG---VPGAAGLPGP 291

Query: 625 IANGFPPGGPG--GPKGMQHFPPGPGGP-MPGPHGGPGGPVGPRLLGPPPPP-RGGDPFW 680
                  G PG  GP G+   P G G P +PGP G  G    P LLG    P   G+P  
Sbjct: 292 QGPSGAKGEPGTRGPPGLIG-PTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGE 350

Query: 681 DGP-------------GDPMRGGPM----RGGPGPGPG-PYHRGRGGRGGNEPPPPPPPF 722
            GP             G P R GP       GPG  PG P  RG  G  G    P  P  
Sbjct: 351 QGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGE 410

Query: 723 RGARGGRSGGGP------PNGRGGPGG-GMVGGGGHRPHEGPGG--GMGNSSGHRPHEGP 773
           RG  G     GP      P   G PGG G+ G  G +   G  G  G+   SG    +GP
Sbjct: 411 RGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGP 470

Query: 774 GGGMGSGHRPH------------EGPGGSMGGGGGHRPHEGPGG-GISGGSGHRPHEGPG 820
            G +G    P             EG  G  G  G   P   PG  GI+G  G     GP 
Sbjct: 471 AGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPP 530

Query: 821 GGMGA------GGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPH 857
           G  GA       G H P+ G  G++ G GG +P  G G    H
Sbjct: 531 GAPGAFDETGIAGLHLPNGGVEGAVLGKGG-KPQFGLGELSAH 572


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score =  116 bits (291), Expect = 9e-26
 Identities = 132/399 (33%), Positives = 154/399 (38%), Gaps = 58/399 (14%)

Query: 539 PGGSG-GSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMG-----SP 592
           PG  G   P GA G + P   +   GS G    P  PG  G         + G      P
Sbjct: 530 PGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGP 589

Query: 593 NSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMP 652
              P E+    P  S  I+      GL  PGP  +   PG PG   G    P   G P  
Sbjct: 590 LGAPGEDGRPGPPGSIGIRGQPGSMGL--PGPKGSSGDPGKPG-EAGNAGVPGQRGAPGK 646

Query: 653 GPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGG 712
               GP GPVGP       P   G+    GP  P      +G PGP PGP   G GG+ G
Sbjct: 647 DGEVGPSGPVGP-------PGLAGERGEQGPPGPTG---FQGLPGP-PGP--PGEGGKPG 693

Query: 713 NEPPPPPPPFRGARGGRSGGGPPNGRGGPG-GGMVG----GGGHRPHEGPGGGMGNSSGH 767
           ++  P  P   G  G R   G P  RG PG  G+ G     GGH P +GP G  G  SG 
Sbjct: 694 DQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGP-DGPKGSPG-PSGT 751

Query: 768 RPHEGPGGGMG-SGHRPHEGPGGSMG--GGGGHRPHEGPGG--------------GISGG 810
               GP G  G  G R   G  G  G  GG G +  EG  G              G +G 
Sbjct: 752 PGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGP 811

Query: 811 SGHRPHEGPGGGMGAGG-----GHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVP 865
           +G +   GP G +G  G     G R   GP G++G +G   P   PG  G  G      P
Sbjct: 812 TGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGE-----P 866

Query: 866 GHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDGGHSHGG 904
           G +G D   P P    G  GP HG  G  G  GG    G
Sbjct: 867 GQKG-DAGSPGPQGLAGSPGP-HGPNGVPGLKGGRGTQG 903



 Score =  114 bits (286), Expect = 3e-25
 Identities = 142/406 (34%), Positives = 158/406 (38%), Gaps = 97/406 (23%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
            P GS G+P G+ G   P       G++G   GPQGP G           + G P     +
Sbjct: 826  PPGSRGNP-GSRGENGPT------GAVGFA-GPQGPDGQ--------PGVKGEPGEPGQK 869

Query: 599  ELLKQPDYSDKIKQMLVPHGLLG-PGPIA-NGFP--PGGPG--GPKGMQHFPPGPG--GP 650
                 P           P GL G PGP   NG P   GG G  GP G   FP   G  GP
Sbjct: 870  GDAGSPG----------PQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGP 919

Query: 651  MPGPHGGPGGPVGPRLLGPP----PPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRG 706
             PGP G PG P GP  LG P    PP   GDP     G   R G  RG  GP  GP  +G
Sbjct: 920  -PGPAGAPG-PAGP--LGEPGKEGPPGLRGDP-----GSHGRVGD-RGPAGPPGGPGDKG 969

Query: 707  RGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRG--------GPGG--GMVGGGGHRPHEG 756
              G  G   P  PP   G  G R   G P  RG        GP G  G VG  G    +G
Sbjct: 970  DPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKG 1029

Query: 757  PGGGMGNSSGHRP-----HEGPGGGMGS----------GHRPHEGPG---GSMGGGGGHR 798
            P G +G    + P      EGP G  G+          G R   GP    GS G  G   
Sbjct: 1030 PPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPG 1089

Query: 799  PHEGPG-GGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMG--------GSGGHRPHE 849
            P   PG  G  G  G R   GP G  G  G   P +GP G  G        G  GHR   
Sbjct: 1090 PVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGP-QGPRGDKGDHGDRGDRGQKGHRGFT 1148

Query: 850  G----PGHGGPHGHR-PHDVPGHRGHDHRGPP----PHEHRGHDGP 886
            G    PG  GP+G +    +PG  G   RGPP    P    G+ GP
Sbjct: 1149 GLQGLPGPPGPNGEQGSAGIPGPFG--PRGPPGPVGPSGKEGNPGP 1192



 Score =  107 bits (266), Expect = 7e-23
 Identities = 146/427 (34%), Positives = 174/427 (40%), Gaps = 77/427 (18%)

Query: 538 EPG------GSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGG-GINVQEILTSIMG 590
           EPG      G  G P  AG    PP      G  G  KG  GP G  GI+ +  +    G
Sbjct: 117 EPGLVPVVTGIRGRPGPAG----PPGSQGPRGERGP-KGRPGPRGPQGIDGEPGVPGQPG 171

Query: 591 SPN-----SHPSEELLKQPDYSDKIKQMLVPHGL-----LGPGPIANGFPPGGPGGPKGM 640
           +P      SHP  + L +P +S ++  +    GL     L PG +     P GP GP+G+
Sbjct: 172 APGPPGHPSHPGPDGLSRP-FSAQMAGLDEKSGLGSQVGLMPGSVG----PVGPRGPQGL 226

Query: 641 --QHFPPGPGGPMPGPHGGPG--GPVGPRLLGPPPPP----RGGDPFWDG-PGD-PMRGG 690
             Q    GP GP PG  G PG  GP+G R  GP  PP      G+P  +G PG+    G 
Sbjct: 227 QGQQGGAGPTGP-PGEPGDPGPMGPIGSR--GPEGPPGKPGEDGEPGRNGNPGEVGFAGS 283

Query: 691 P-MRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGP--PNGRGGPGGGMVG 747
           P  RG PG    P  +G  G  G E P       GA G +   GP  P G  GP G   G
Sbjct: 284 PGARGFPGAPGLPGLKGHRGHKGLEGPKGEV---GAPGSKGEAGPTGPMGAMGPLGPR-G 339

Query: 748 GGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGS-MGGGGGHRPHEGPGG- 805
             G R   GP G  G    H    G  G MG    P   PG S   G  G +   GP G 
Sbjct: 340 MPGERGRLGPQGAPGQRGAH-GMPGKPGPMG----PLGIPGSSGFPGNPGMKGEAGPTGA 394

Query: 806 -GISGGSGHRPHEGPGGGMGAGG--------GHRPHEGPGGSMGGSGGHRPHEGPGHGGP 856
            G  G  G R   GP G +G+ G        G    +GP GS G SG       PG  GP
Sbjct: 395 RGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGP 454

Query: 857 HGH--------RPHD--VPGHRGH-DHRGPP-PHEHRGHDGP--GHGGGGHRGHDGGHSH 902
            G         +P D  VPG +G    +G P PH  +G  GP    G  G RG  G    
Sbjct: 455 QGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGP 514

Query: 903 GGDMSNR 909
            G +  R
Sbjct: 515 PGPVGER 521



 Score =  102 bits (255), Expect = 1e-21
 Identities = 126/370 (34%), Positives = 139/370 (37%), Gaps = 68/370 (18%)

Query: 539  PGGSGGSPD--GAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHP 596
            P G  G P   G  G++ PP      GS G   GP GP G       +     G P    
Sbjct: 886  PHGPNGVPGLKGGRGTQGPPGATGFPGSAGR-VGPPGPAGAPGPAGPL-----GEPGKEG 939

Query: 597  SEELLKQPDYSDKIKQMLVPHGLLGP-GPIANGFPPGGPGGPKGMQHFPPGPGGPMPGPH 655
               L   P            HG +G  GP     PPGGPG  KG     PG  G  PGP 
Sbjct: 940  PPGLRGDPG----------SHGRVGDRGPAG---PPGGPGD-KG----DPGEDG-QPGPD 980

Query: 656  G--GPGGPVGPRLLGPPPPPRG--GDPFWDGP-GDPMRGGPM-----RGGPGP-GP---- 700
            G  GP G  G R +   P  RG  G P   GP G P + GP      +G PGP GP    
Sbjct: 981  GPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSN 1040

Query: 701  GPYHR-GRGGRGGNEPPPPPPPFRGARGGRSGGGP---PNGRGGPGG----GMVGGGGHR 752
            GP    G  G  GN+  P      G RG R   GP   P  +G PG     G  G  G R
Sbjct: 1041 GPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQR 1100

Query: 753  PHEGPGGGMG--NSSGHRPHEGPGGGMGS----------GHRPHEGPGGSMGGGGGHRPH 800
               G  G +G    +G R   GP G  G           G + H G  G  G  G   P+
Sbjct: 1101 GDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPN 1160

Query: 801  EGPGG-GISGGSGHRPHEGPGGGMGAGGGHRPHE--GPGGSMGGSGGHRPHEGPGHGGPH 857
               G  GI G  G R   GP G  G  G   P    GP G  G  G   P   PG  GP 
Sbjct: 1161 GEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPP 1220

Query: 858  GHRPHDVPGH 867
            G  P   PGH
Sbjct: 1221 G--PPGPPGH 1228



 Score =  100 bits (248), Expect = 8e-21
 Identities = 133/427 (31%), Positives = 160/427 (37%), Gaps = 75/427 (17%)

Query: 539 PGGSGGSPDGAGGSKLPPVLANLMGSMG--AGKGPQG----PGGGGINVQEILTSIMGSP 592
           PG  G  P G+ G+  PP  A   GS G     GPQG    PG  G+   +      G P
Sbjct: 428 PGAKG--PTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEP 485

Query: 593 NSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPG--------GPKGMQ--H 642
             H  +  +  P    K      P  +  PGP+     PG  G        GPKG Q   
Sbjct: 486 GPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGER 545

Query: 643 FPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRG--GDPFWDGPGDPMRGGPMRGGPG--- 697
            P G  GP  G  G PG P  P L    P  RG  G+P   GP   +  GP+ G PG   
Sbjct: 546 GPVGSSGPK-GSQGDPGRPGEPGL----PGARGLTGNPGVQGPEGKL--GPL-GAPGEDG 597

Query: 698 -PGPG--------PYHRGRGGRGGNEPPPPPPPFRGARG--GRSGGGPPNGRGGPGG--G 744
            PGP         P   G  G  G+   P  P   G  G  G+ G    +G  GP G  G
Sbjct: 598 RPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVG 657

Query: 745 MVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMG--GGGGHRPHEG 802
             G  G R  +GP G  G      P   PG G   G +   G  G++G  G  G R + G
Sbjct: 658 PPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPG 717

Query: 803 PGG--GISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGH------G 854
             G  GI+G  G +   G  GG G  G  +   GP G+ G +G       PG        
Sbjct: 718 ERGEPGITGLPGEK---GMAGGHGPDGP-KGSPGPSGTPGDTGPPGLQGMPGERGIAGTP 773

Query: 855 GPHGHR----PHDVPGHRGHDHR-------GPP----PHEHRGHDGPGH--GGGGHRGHD 897
           GP G R         G  G+D         GPP    P   +G  GP    G  G RG+ 
Sbjct: 774 GPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNP 833

Query: 898 GGHSHGG 904
           G     G
Sbjct: 834 GSRGENG 840



 Score = 94.7 bits (234), Expect = 3e-19
 Identities = 145/450 (32%), Positives = 162/450 (36%), Gaps = 104/450 (23%)

Query: 541  GSGGSP--DGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
            G  G+P  DG  G   P     L G  G  +GP GP G           + G P   P  
Sbjct: 639  GQRGAPGKDGEVGPSGPVGPPGLAGERGE-QGPPGPTG--------FQGLPGPPG--PPG 687

Query: 599  ELLKQPDYSDKIKQMLVPHGLLGP-GPIANGFPPGGPG-----GPKGMQ--HFPPGPGGP 650
            E  K  D         V  G LGP G   N    G PG     G KGM   H P GP G 
Sbjct: 688  EGGKPGDQGVPGDPGAV--GPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGS 745

Query: 651  MPGPHGGPGGPVGPRLLGPP--------PPPRG-----GDPFWDGPG--DPMRGGPMRGG 695
             PGP G PG    P L G P        P P+G     G+   +G    D  RG P   G
Sbjct: 746  -PGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLG 804

Query: 696  PGPGP-GPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGP-----------PNGRGGPGG 743
            P PGP GP   G  G  G      PP  RG  G R   GP           P+G+ G  G
Sbjct: 805  P-PGPAGP--TGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKG 861

Query: 744  --GMVGGGGHRPHEGPGGGMGNSSGHRPH-----------EGPGGGMG----SGHRPHEG 786
              G  G  G     GP G  G+   H P+           +GP G  G    +G     G
Sbjct: 862  EPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPG 921

Query: 787  PGGSMGGGG--GHRPHEGPGG-----GISGGSGHRPHEGPGGGMGAGG-----GHRPHEG 834
            P G+ G  G  G    EGP G     G  G  G R   GP GG G  G     G    +G
Sbjct: 922  PAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDG 981

Query: 835  PGGSMGGSG--------GHRPHEG-PGHGGPHGHRPHDVPGHRGHDHRGPP--------- 876
            P G  G +G        G R   G PG  GP G  P  V        +GPP         
Sbjct: 982  PPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAG-TPGKVGPTGATGDKGPPGPVGPPGSN 1040

Query: 877  -PHEHRGHDGPGHGGGGHRGHDGGHSHGGD 905
             P    G +GP  G  G  G DG     GD
Sbjct: 1041 GPVGEPGPEGPA-GNDGTPGRDGAVGERGD 1069



 Score = 87.0 bits (214), Expect = 7e-17
 Identities = 135/435 (31%), Positives = 151/435 (34%), Gaps = 82/435 (18%)

Query: 539 PGGSGGSPDGAGGSKLP--PVLANLMGSMGAGKGPQGPGGG-------GINVQEILTSIM 589
           P G  G   GAG +  P  P     MG +G+ +GP+GP G        G N         
Sbjct: 223 PQGLQGQQGGAGPTGPPGEPGDPGPMGPIGS-RGPEGPPGKPGEDGEPGRNGNPGEVGFA 281

Query: 590 GSPNSH--PSEELLKQPDYSDKIKQMLVPHGLLG-PGPIANGFPPG-----GPGGPKGMQ 641
           GSP +   P    L         K +  P G +G PG      P G     GP GP+GM 
Sbjct: 282 GSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGM- 340

Query: 642 HFPPGPGGPMPGPHGGPG-----------GPVGPRLLGPPPPPRGGDPFWDGPGDPMRGG 690
              PG  G + GP G PG           GP+GP  LG P    G   F   PG     G
Sbjct: 341 ---PGERGRL-GPQGAPGQRGAHGMPGKPGPMGP--LGIP----GSSGFPGNPGMKGEAG 390

Query: 691 PM--------------RGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPN 736
           P                G PGP   P   G  G  G      P    G  G     GPP 
Sbjct: 391 PTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPG 450

Query: 737 GRGGPGGGMVGGGGHRPHEGPGG--GMGNSSGHRPHEGPGGGMGS-GHRPHEGPGGSMGG 793
             G  G    G  G R   G  G  G    +G +   GP G  G  G    EG  G  G 
Sbjct: 451 SPGPQGS--TGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGD 508

Query: 794 GGGHRPHEGPGG--GISGGSGHRPHEGPGGGMGAGGGHRP--HEGPGGSMGGSGGHRPHE 849
            G   P  GP G  G  G  G    +G  G  GA G   P    GP GS G  G  RP E
Sbjct: 509 PGTVGP-PGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPG--RPGE 565

Query: 850 -----------GPGHGGPHGH-RPHDVPGHRGHDHRGPPPH-EHRGHDGPGHGGGGHRGH 896
                       PG  GP G   P   PG  G    GPP     RG  G   G  G +G 
Sbjct: 566 PGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRP--GPPGSIGIRGQPG-SMGLPGPKGS 622

Query: 897 DGGHSHGGDMSNRPV 911
            G     G+  N  V
Sbjct: 623 SGDPGKPGEAGNAGV 637



 Score = 77.0 bits (188), Expect = 8e-14
 Identities = 107/345 (31%), Positives = 122/345 (35%), Gaps = 100/345 (28%)

Query: 539  PGGSGGSPDGAG-----GSKLPPVLANLMGSMG--AGKGPQGPGGG-------------- 577
            P G  G+P  AG     G + PP L    GS G    +GP GP GG              
Sbjct: 919  PPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPG 978

Query: 578  --------GINVQEILTSIMGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLG----PGPI 625
                    G   Q  +  + G         L        K+     P G  G    PGP+
Sbjct: 979  PDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVG----PTGATGDKGPPGPV 1034

Query: 626  ANGFPPG--------GPGGPKGMQHFP--------------PGPGGPMPGPHGGPG--GP 661
                PPG        GP GP G    P              PGP G +PG  G PG  GP
Sbjct: 1035 G---PPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAG-LPGSQGAPGTPGP 1090

Query: 662  VGPRLLGPPPPPRGGDPFWDGP-GDPMRGGPMRGGPGP----GPGPYHRGRGGRG----- 711
            VG     P    + GDP   GP G P R G  RG PGP    G    H  RG RG     
Sbjct: 1091 VG----APGDAGQRGDPGSRGPIGPPGRAGK-RGLPGPQGPRGDKGDHGDRGDRGQKGHR 1145

Query: 712  ---GNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHR 768
               G +  P PP   G +G     GP   RG PG   VG  G   + GP G +G      
Sbjct: 1146 GFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGP--VGPSGKEGNPGPLGPIG------ 1197

Query: 769  PHEGPGGGMGS-GHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSG 812
                P G  GS G    EGP G  G  G      GP G ++   G
Sbjct: 1198 ----PPGVRGSVGEAGPEGPPGEPGPPG----PPGPPGHLTAALG 1234



 Score = 70.5 bits (171), Expect = 7e-12
 Identities = 72/226 (31%), Positives = 80/226 (35%), Gaps = 28/226 (12%)

Query: 698 PGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGP 757
           PG G  + GRG +G    P   P   G RG     GPP G  GP G      G +   GP
Sbjct: 100 PGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPP-GSQGPRGER----GPKGRPGP 154

Query: 758 GGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHE 817
            G  G          PG     GH  H GP G        RP      G+   SG     
Sbjct: 155 RGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLS------RPFSAQMAGLDEKSGLGSQV 208

Query: 818 GPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHG-------HRPHDVPGHRGH 870
           G   G     G R  +G  G  GG+G   P   PG  GP G         P   PG  G 
Sbjct: 209 GLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGE 268

Query: 871 DHRGPPPHE--------HRGHDG-PGHGG-GGHRGHDGGHSHGGDM 906
             R   P E         RG  G PG  G  GHRGH G     G++
Sbjct: 269 PGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEV 314



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 87/267 (32%), Positives = 100/267 (37%), Gaps = 65/267 (24%)

Query: 539  PGGSGGS--PDGAGGSKLPPVLANLMGSMG--AGKGPQGPGGGGINVQEILTSIMGSPNS 594
            P G+ G   P GA G K PP      GS G     GP+GP G             G+P  
Sbjct: 1012 PAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGND-----------GTPGR 1060

Query: 595  HPSEELLKQPDYSDKIKQMLVPHGLLG-------PGPIANGFP--------PG--GPGGP 637
              +  + ++ D  D       P GL G       PGP+  G P        PG  GP GP
Sbjct: 1061 DGA--VGERGDRGDP-----GPAGLPGSQGAPGTPGPV--GAPGDAGQRGDPGSRGPIGP 1111

Query: 638  KGM--QHFPPGPGGPM--PGPHGGPG--GPVGPR----LLGPPPPPRGGDPFWDGPGDPM 687
             G   +   PGP GP    G HG  G  G  G R    L G P PP G +      G P 
Sbjct: 1112 PGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPP-GPNGEQGSAGIPG 1170

Query: 688  RGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG-GGMV 746
              GP RG PGP       G  G+ GN  P  P    G RG     GP    G PG  G  
Sbjct: 1171 PFGP-RGPPGPV------GPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPP 1223

Query: 747  GGGGHRPHEGPGGGMGNSSGHRPHEGP 773
            G  GH         +G+  GH     P
Sbjct: 1224 GPPGHLT-----AALGDIMGHYDESMP 1245


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  115 bits (287), Expect = 2e-25
 Identities = 142/433 (32%), Positives = 153/433 (35%), Gaps = 116/433 (26%)

Query: 539  PGGSGGSP--DGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHP 596
            P G  G P  DG  G+K  P  A   G  G   GP GP G    +  +     G+P +  
Sbjct: 810  PAGFAGPPGADGQPGAKGEPGDAGAKGDAGP-PGPAGPAGPPGPIGNV-----GAPGAKG 863

Query: 597  SEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPG----GPGGPKGMQHFPPGPGGPMP 652
            +                    G  GP P A GFP      GP GP G    PPGP GP  
Sbjct: 864  AR-------------------GSAGP-PGATGFPGAAGRVGPPGPSGNAG-PPGPPGPA- 901

Query: 653  GPHGGPG-----GPVG-PRLLGPPPPP----RGGDPFWDGP-GDPMRGGPM--------- 692
            G  GG G     GP G P  +GPP PP      G P  DGP G P   GP          
Sbjct: 902  GKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVV 961

Query: 693  --------RGGPG-PGPG--PYHRGRGGRGGNEPPPPP--PPFRGARGGRSGG-GPPNGR 738
                    RG PG PGP   P  +G  G  G   PP P  PP      G SG  G P   
Sbjct: 962  GLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAE 1021

Query: 739  GGPG-GGMVGGGGHRPHEGPGG--------------GMGNSSGHRPHEGPGGGMGS---- 779
            G PG  G  G  G R   GP G              G    SG R   GP G  G     
Sbjct: 1022 GSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPV 1081

Query: 780  GHRPHEGPGGSMGGGG-----------GHRPHEG-------PGG----GISGGSGHRPHE 817
            G R   GP G  G  G           GHR   G       PG     G SG SG     
Sbjct: 1082 GARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPR 1141

Query: 818  GPGGGMGAGG-----GHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDH 872
            GP G  GA G     G     GP G  G +G   P   PG  GP G  P   P       
Sbjct: 1142 GPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPG--PPGPPSAGFDFS 1199

Query: 873  RGPPPHEHRGHDG 885
              P P + + HDG
Sbjct: 1200 FLPQPPQEKAHDG 1212



 Score =  112 bits (279), Expect = 2e-24
 Identities = 137/429 (31%), Positives = 153/429 (35%), Gaps = 83/429 (19%)

Query: 539 PGGSGGSPDGAG--GSKLPPVLANLMGSMGA----GK-GPQGPGGGGINVQEILTSIMGS 591
           P G  GSP  AG  G    P    L GS G+    GK GP GP G     Q+      G 
Sbjct: 516 PAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAG-----QDGRPGPPGP 570

Query: 592 PNSHPSEELLKQPDYSDKIKQMLVPHGLLG-PGPIANGFPPGGPG--GPKGMQ-----HF 643
           P +     ++  P           P G  G PG       PG PG  GP G         
Sbjct: 571 PGARGQAGVMGFPG----------PKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQG 620

Query: 644 PPGPGGPMP--GPHGGPGGPVGPRLLGPPPPP-RGGDPFWDG-PGDPMRGGPMRGGPGPG 699
           PPGP GP    G  G  G P    L GP  PP   G P   G PGD        G PGP 
Sbjct: 621 PPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGD-------LGAPGPS 673

Query: 700 PGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGG-GMVGGGGHR--PHEG 756
                RG  G  G + PP P   RGA G     G     G PG  G  G  G +  P E 
Sbjct: 674 GARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGER 733

Query: 757 PGGGMGNSSGHRPHEGPGGGMGS----GHRPHEGPGGSMG--GGGGHRPHEGPGG----- 805
              G+    G R   GP G  GS    G R   GP G  G  G  G +   GP G     
Sbjct: 734 GAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPT 793

Query: 806 GISGGSGHRPHEGPGGGMGAGG--------GHRPHEGPGGSMGGSGGHRPHEGPGHGGPH 857
           G  G  G R   GP G  G  G        G +   G  G+ G +G   P    G  GP 
Sbjct: 794 GARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPI 853

Query: 858 GH-------------RPHDVPGHRGHDHR-GPP-PHEHRGHDGP-----GHGGGGHRGHD 897
           G+              P    G  G   R GPP P  + G  GP       GG G RG  
Sbjct: 854 GNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGET 913

Query: 898 GGHSHGGDM 906
           G     G++
Sbjct: 914 GPAGRPGEV 922



 Score =  109 bits (273), Expect = 1e-23
 Identities = 119/348 (34%), Positives = 134/348 (38%), Gaps = 72/348 (20%)

Query: 618 GLLGPGPIANGFPPGGPGGPKGMQHFP-----PGPGGPMPGPHGGPG------------- 659
           G+ GP        P GP GP G    P     PGP GP PGP G PG             
Sbjct: 109 GVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGP-PGPPGPPGLGGNFAPQLSYGY 167

Query: 660 --------------GPVGPR-LLGPP--PPPRGGDPFWDGPGDPMRGGPM--RGGPGPGP 700
                         GP GPR L GPP  P P+G       PG+P   GPM  RG PGP P
Sbjct: 168 DEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGP-P 226

Query: 701 GPY----HRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG-GGMVGGGGHRPHE 755
           G        G+ GR G   PP P   +GARG     G P  +G  G  G+ G  G     
Sbjct: 227 GKNGDDGEAGKPGRPGERGPPGP---QGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPA 283

Query: 756 GPGG--GMGNSSGHRPHEGPGGGMGSGHRP-HEGPGGSMG-----GGGGHRPHEGPGG-- 805
           GP G  G    +G     GP G  G   RP   GP G+ G     G  G     GP G  
Sbjct: 284 GPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPP 343

Query: 806 GISGGSGHRPHEGPGGGMGAGG--GHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHR-PH 862
           G  G  G +   GP G  G+ G  G R   GP G  G +G   P   PG  G  G +  +
Sbjct: 344 GFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAG---PAGNPGADGQPGAKGAN 400

Query: 863 DVPGHRGHDHRGPPPHEHRGHDGPGHGGG-----GHRGHDGGHSHGGD 905
             PG  G     P     RG  GP   GG     G+ G  G     GD
Sbjct: 401 GAPGIAG----APGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGD 444



 Score =  109 bits (273), Expect = 1e-23
 Identities = 129/405 (31%), Positives = 145/405 (35%), Gaps = 96/405 (23%)

Query: 540 GGSGGS-PDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
           G +G + P G  G   PP     +G+ G   GPQGP G      E    + G P      
Sbjct: 326 GATGAAGPPGPTGPAGPPGFPGAVGAKGEA-GPQGPRGS-----EGPQGVRGEPGP---- 375

Query: 599 ELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPG-----GPKGMQHFPPGPGGP-MP 652
                                  PGP     P G PG     G KG    P   G P  P
Sbjct: 376 -----------------------PGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFP 412

Query: 653 GPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGG 712
           G  G P GP GP   G PP P+G        G+P       G PG       +G  G  G
Sbjct: 413 GARG-PSGPQGP---GGPPGPKGNS------GEP-------GAPGSKGDTGAKGEPGPVG 455

Query: 713 NEPPPPPPPFRGARGGRSG------GGPPNGRGGPG----------GGMVGGGGHRPHEG 756
            + PP P    G RG R         GPP  RGGPG           G  G  G R   G
Sbjct: 456 VQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPG 515

Query: 757 PGGGMGN-SSGHRPHEG--PGGGMGSGHRPHEGPGGSMG--GGGGHRPHEGPGG--GISG 809
           P G  G+     RP E   PG    +G     GP G  G  G  G     GP G  G  G
Sbjct: 516 PAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARG 575

Query: 810 GSGHRPHEGPGGGMGAGG--GHRPHEGPGGSMG--GSGGHRPHEG-PGHGGPHGHR---- 860
            +G     GP G  G  G  G R   GP G++G  G  G    +G PG  GP G R    
Sbjct: 576 QAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQG 635

Query: 861 PHDVPGHRGHDHRGPPPHE--HRGHDG-PGH----GGGGHRGHDG 898
           P   PG +G      PP E    G  G PG     G  G RG  G
Sbjct: 636 PAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERG 680



 Score = 99.0 bits (245), Expect = 2e-20
 Identities = 140/472 (29%), Positives = 164/472 (34%), Gaps = 131/472 (27%)

Query: 541  GSGGSPDGAGGSKLPPVLANLMGSMGAG--KGPQGP-GGGGINVQEILTSIMGSPNSHPS 597
            G  G+P GA GS+  P L  + G  GA    GP+G  G  G    +      GSP     
Sbjct: 710  GDAGAP-GAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGAD------GSPGK--- 759

Query: 598  EELLKQPDYSDKIKQMLVPHGLLGPGPIANGFP-------PGGPGGPKGMQHFP-----P 645
                      D ++ +  P G  GP     G P       P GP GP G +  P     P
Sbjct: 760  ----------DGVRGLTGPIGPPGPA----GAPGDKGESGPSGPAGPTGARGAPGDRGEP 805

Query: 646  GPGGPM-----PGPHGGPG-----GPVGPRLLGPPPPPRGGDPFWDGPGDPMR--GGP-- 691
            GP GP      PG  G PG     G  G +    PP P G      GP  P+   G P  
Sbjct: 806  GPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPA----GPPGPIGNVGAPGA 861

Query: 692  --MRGGPGPGPGPYHRGRGGR-------GGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG 742
               RG  GP       G  GR       G   PP PP P      G+ GG  P G  GP 
Sbjct: 862  KGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGP-----AGKEGGKGPRGETGPA 916

Query: 743  G-----------GMVGGGGHRPHEGPGGGMGNS-----SGHRPHEGPGGGMGS-GHRPHE 785
            G           G  G  G    +GP G  G       +G R   G  G  G  G     
Sbjct: 917  GRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLP 976

Query: 786  GPGGSMG-----GGGGHRPHEGPGG--GISGGSGHRPHEGPGGGMGAGG--------GHR 830
            GP G  G     G  G R   GP G  G++G  G    EG  G  G+ G        G R
Sbjct: 977  GPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDR 1036

Query: 831  PHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGP--GH 888
               GP G  G  G       PG  GP G  P    G RG      P     G  GP    
Sbjct: 1037 GETGPAGPPGAPG------APGAPGPVG--PAGKSGDRGETGPAGP----AGPVGPVGAR 1084

Query: 889  GGGGHRGHDGGHSHGGDMSNRPVCRHFMMKGNCRYENNCAFYHPGVNGPPLP 940
            G  G +G  G     G+  +R +      KG+  +         G+ GPP P
Sbjct: 1085 GPAGPQGPRGDKGETGEQGDRGI------KGHRGFS--------GLQGPPGP 1122



 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 75/234 (32%), Positives = 82/234 (35%), Gaps = 43/234 (18%)

Query: 538  EPGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPS 597
            EPG  G  P GA G + PP     MG  G   GP G  G     +E      GSP    S
Sbjct: 981  EPGKQG--PSGASGERGPP---GPMGPPGLA-GPPGESG-----REGAPGAEGSPGRDGS 1029

Query: 598  EELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGPHG- 656
                     +        P     PGP+     P G  G +G +  P GP GP+ GP G 
Sbjct: 1030 PGAKGDRGETGPAGPPGAPGAPGAPGPVG----PAGKSGDRG-ETGPAGPAGPV-GPVGA 1083

Query: 657  -GPGGPVGPR----------------------LLGPPPPPRGGDPFWDGPGDPMRGGPMR 693
             GP GP GPR                      L GPP PP  G P   GP         R
Sbjct: 1084 RGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPP--GSPGEQGPSGASGPAGPR 1141

Query: 694  GGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVG 747
            G PG    P   G  G  G   PP P    G  G     GPP   G PG    G
Sbjct: 1142 GPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAG 1195


>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
          Length = 1336

 Score =  115 bits (287), Expect = 2e-25
 Identities = 157/532 (29%), Positives = 195/532 (36%), Gaps = 116/532 (21%)

Query: 433  AKREILSDRHA---FETARRLSHDNMEEKVPWVCPRPLVLPSPLVTPGSNSQERYIQAER 489
            A  E+L+DR      E  ++   +  +E        P +L    +   +  Q   IQ   
Sbjct: 517  APNEVLNDRKEDIKLEEKKKTQAEIEQEMATLQYTNPQLLEQLKIERLAQKQVEQIQPPP 576

Query: 490  EKG--ILQELFLNKESPHEPDPEPYE-PIPPKLIPLDEECSMDETPYVETLEPGGSGGSP 546
              G  +L       + P    P+ ++ P P + +P++        P  +   PG     P
Sbjct: 577  SSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPG-----P 631

Query: 547  DGAGGSKLPPVLANLMGSMG--AGKGPQGPGGGGINVQEILTSIMGSPNSHPSEELLKQP 604
             G  G + PP+     G  G    +GPQGP  G    Q++          H  + + + P
Sbjct: 632  QGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDM----------HGPQGMQRHP 681

Query: 605  DYSDKIKQMLVPHGLLGP----GPIANGFPPG--GPGGPKGMQ-HFPPGPGGPMPGPHG- 656
                       PHG LGP    GP  +  P G  GP GP G Q H   GP GP PGP G 
Sbjct: 682  G----------PHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHI--GPQGP-PGPQGH 728

Query: 657  -GPGGPVGPRLLGPPPPPRG-----------GDPFWDGPGDPMRGGP--------MRGGP 696
             GP GP G + +  PP PRG           G P   G   P+  GP        M+G P
Sbjct: 729  LGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPP 788

Query: 697  GP----GP---------------GPYHRG----------RGG---RGGNEPPP------P 718
            GP    GP               GP+  G          RG    RG   PPP      P
Sbjct: 789  GPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGP 848

Query: 719  PPPFRGARGGRSGGGPPNGRGG--PGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGG 776
            P   RG  G +S  GPP G  G  P GGM G  G +  + P  G   S G  P +     
Sbjct: 849  PQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTP 908

Query: 777  -MGSGHR-PHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEG 834
             +G G R P    G S G      P   PG G  G  G  P   PG G G   G     G
Sbjct: 909  LLGDGPRAPFNQEGQSTG-----PPPLIPGLGQQGAQGRIPPLNPGQGPGPNKG--DSRG 961

Query: 835  PGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGP 886
            P     G    R HE    GGP  H P   P   G D RGPP       D P
Sbjct: 962  PPNHHMGPMSERRHE--QSGGPE-HGPERGPFRGGQDCRGPPDRRGPHPDFP 1010



 Score = 74.7 bits (182), Expect = 4e-13
 Identities = 76/225 (33%), Positives = 86/225 (38%), Gaps = 37/225 (16%)

Query: 671 PPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPP-PFRGARGGR 729
           PPP  G P                GP P PG     +  +G  +P P    P   A+ G 
Sbjct: 574 PPPSSGTPLL--------------GPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGP 619

Query: 730 SGGGPPNGRGGPGG--GMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGP 787
            G   P G+  P G  G +G  G   H+G GG  G      P +GP  G+      H GP
Sbjct: 620 PG---PQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGP-QGPPQGLPRPQDMH-GP 674

Query: 788 GGSMGGGGGHRPHEGPGG--GISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGH 845
            G     G H P  GP G  G  G SG + H GP G  G  G    H GP G  G  G  
Sbjct: 675 QGMQRHPGPHGPL-GPQGPPGPQGSSGPQGHMGPQGPPGPQG----HIGPQGPPGPQGHL 729

Query: 846 RPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGG 890
            P   PG  G  G      PG RG      PPH H    GPG  G
Sbjct: 730 GPQGPPGTQGMQGP-----PGPRGMQG---PPHPHGIQGGPGSQG 766



 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 135/485 (27%), Positives = 151/485 (31%), Gaps = 134/485 (27%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
            P GS G P   GG + PP      G     +GP  P  G I  Q+  T ++G     P  
Sbjct: 865  PQGSLGPPP-QGGMQGPP---GPQGQQNPARGPH-PSQGPIPFQQQKTPLLGDGPRAPFN 919

Query: 599  ELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPP----GP------- 647
            +   Q      +   L   G  G  P  N  P  GPG  KG    PP    GP       
Sbjct: 920  QE-GQSTGPPPLIPGLGQQGAQGRIPPLN--PGQGPGPNKGDSRGPPNHHMGPMSERRHE 976

Query: 648  --GGPMPGPHGGPGGPVGPRLLGPP----PPPRGGDPFWDGPGD--------------PM 687
              GGP  GP  GP    G    GPP    P P   D F   P D                
Sbjct: 977  QSGGPEHGPERGPFRG-GQDCRGPPDRRGPHPDFPDDF-SRPDDFHPDKRFGHRLREFEG 1034

Query: 688  RGGPM-------RGGPGPGPGPYHR------GRGGRGGNEPP----------------PP 718
            RGGP+       RGGPGP   P HR      GRG   G  PP                P 
Sbjct: 1035 RGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARG--PPGAWEGRRPGDERFPRDPE 1092

Query: 719  PPPFRGARGG---------RSGGGPPNGRGG-PGGGMVGGGGH--------RPHEGPGGG 760
             P FRG R             G  PP GR G PG    G   +        R  +  G G
Sbjct: 1093 DPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRG 1152

Query: 761  MGNSSGHR------PHEGPGGGMGSGHRPHEGPGGSMGGGG----------GHRPHEG-- 802
             G   G R      P E P      G +P    G    G G           H PH+G  
Sbjct: 1153 RGTPRGGRKGLLPTPDEFPR--FEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPPHDGHS 1210

Query: 803  -----------------------PGGGISGGSGHRPHEGPGG-GMGAGGGHRPHEGPGGS 838
                                   P     G S HR  E PGG     GG  R   GP   
Sbjct: 1211 PASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGPGPAQR 1270

Query: 839  MGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDG 898
            +  SG     +G  H G H   P   P   G   RG     + G     + G   RG   
Sbjct: 1271 VPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPPRRGASR 1330

Query: 899  GHSHG 903
            G   G
Sbjct: 1331 GGGRG 1335



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 58/185 (31%), Positives = 66/185 (35%), Gaps = 27/185 (14%)

Query: 635  GGPKGM----QHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDG--PGDPMR 688
            GG KG+      FP   GG  P    G   P GP        PR   P  DG  P    R
Sbjct: 1158 GGRKGLLPTPDEFPRFEGGRKPDSWDGNREP-GPGHEHFRDTPRPDHPPHDGHSPASRER 1216

Query: 689  GGPMRG----GPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGP-------PNG 737
               ++G       P   P+H G G     E   P  P    RGG+  GGP        +G
Sbjct: 1217 SSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSED-RGGKGRGGPGPAQRVPKSG 1275

Query: 738  RGGPGGGMVGGGGHR--PHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPG--GSMGG 793
            R     G    G HR  P  GP G    S G R     G   G G   + GP   G+  G
Sbjct: 1276 RSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRS----GSNWGRGSNMNSGPPRRGASRG 1331

Query: 794  GGGHR 798
            GG  R
Sbjct: 1332 GGRGR 1336


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score =  114 bits (286), Expect = 3e-25
 Identities = 152/459 (33%), Positives = 174/459 (37%), Gaps = 97/459 (21%)

Query: 539  PGGSGGSPD-GAGGSKLPPVLANLMGSMG--AGKGPQGPGGGGINVQEILTSIMGSPNSH 595
            PG +G + D G  G+  P   A   GS G     GP GP G             G P + 
Sbjct: 684  PGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPA-----GAAGQPGAK 738

Query: 596  PSEELLKQPDYSDKIKQMLVPHGLLGP-GPIANGFPPG-----GPGGPKGMQHFPPGPG- 648
              E   K P   + +     P G  GP GP  NG PPG     G GGP GM  FP   G 
Sbjct: 739  -GERGAKGPKGENGVVGPTGPVGAAGPAGP--NG-PPGPAGSRGDGGPPGMTGFPGAAGR 794

Query: 649  -GPMPGPHG--GPGGPVGPR----LLGPP----PPPRGGDPFWDGP----------GDPM 687
             GP PGP G  GP GP GP     L GP     P  R G+    GP          G+  
Sbjct: 795  TGP-PGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAG 853

Query: 688  RGGPMRGGPGP-----GPG----PYHRGRGGRGG-----NEPPP-----------PP--- 719
              GP  G PGP      PG    P  RG  G  G      EP P           PP   
Sbjct: 854  TAGPP-GTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAV 912

Query: 720  --PPFRGARGGRSGGGPPNGRGGPG-GGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGG 776
              P   GA G     G P   G PG  G  G  G R + G  G +G +    PH GP G 
Sbjct: 913  GSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPH-GPVGP 971

Query: 777  MGS-GHRPHEGPGGSMGGGGGHRPHEGPGG--GISGGSGHRPHEGPGGGMGAGG------ 827
             G  G+R   GP G +G  G   P  GP G  GI G  G    +GP G  G  G      
Sbjct: 972  AGKHGNRGETGPSGPVGPAGAVGP-RGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQG 1030

Query: 828  -----GHRPHEGPGGSMGGSGGHRP--HEGP-GHGGPHGH----RPHDVPGHRGHDHRGP 875
                 GH   +G  GS+G +G   P    GP G  G  GH     P  + G +GH     
Sbjct: 1031 LPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAG 1090

Query: 876  PPHEHRGHDGPGHGGGGHR-GHDGGHSHGGDMSNRPVCR 913
            PP        PG  GGG+  G+DG         + P  R
Sbjct: 1091 PPGPPGPPGPPGVSGGGYDFGYDGDFYRADQPRSAPSLR 1129



 Score =  100 bits (250), Expect = 5e-21
 Identities = 124/396 (31%), Positives = 145/396 (36%), Gaps = 71/396 (17%)

Query: 539 PGGSGG-SPDGAGGSKLPPVLANLMGSMG--AGKGPQG-PGGGGINVQEILTSIMGSPNS 594
           PG  G   P G  G++  P      G++G    KGP G PG  G      L    G+P  
Sbjct: 471 PGIDGRPGPIGPAGARGEP------GNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPG- 523

Query: 595 HPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPM--- 651
                    PD ++  +      G  GP  +  G    GP GP G Q  P GP GP    
Sbjct: 524 ---------PDGNNGAQ------GPPGPQGVQGGKGEQGPPGPPGFQGLP-GPSGPAGEV 567

Query: 652 --PGPHG--------GPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPG 701
             PG  G        GP GP G R  GPP     G+    GP  P+      G PGP   
Sbjct: 568 GKPGERGLHGEFGLPGPAGPRGER--GPP-----GESGAAGPTGPIGSRGPSGPPGPDGN 620

Query: 702 PYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG----GGMVGGGGHRPHEGP 757
               G  G  G   P  P    G RG     G P G+G  G     G +G  G     G 
Sbjct: 621 KGEPGVVGAVGTAGPSGPSGLPGERGA---AGIPGGKGEKGEPGLRGEIGNPGRDGARGA 677

Query: 758 GGGMGNSSGHRPHEGPGGGMGS-GHRPHEGPGGSMG--GGGGHRPHEGPGG--GISGGSG 812
            G +G         GP G  G  G     GP G  G  G  G R   GP G  G +G +G
Sbjct: 678 PGAVG-------APGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAG 730

Query: 813 HRPHEGPGGGMGAGG--GHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGH-RPHDVPGHRG 869
                G  G  GA G  G     GP G +G +G   P+  PG  G  G   P  + G  G
Sbjct: 731 AAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPG 790

Query: 870 HDHRGPPPHEHRGHDGPGHGGGGHRGHDGGHSHGGD 905
              R  PP    G  GP  G  G  G +G     GD
Sbjct: 791 AAGRTGPPGP-SGISGP-PGPPGPAGKEGLRGPRGD 824



 Score =  100 bits (248), Expect = 8e-21
 Identities = 134/418 (32%), Positives = 156/418 (37%), Gaps = 64/418 (15%)

Query: 532 PYVETLEPGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGS 591
           P  E  EPG +G  P GA G   PP  A   G  G    P  PG  G+   +      G+
Sbjct: 116 PAGEPGEPGQTG--PAGARGPAGPPGKAGEDGHPGK---PGRPGERGVVGPQGARGFPGT 170

Query: 592 PNSHPSEELLKQPDYSDKIKQMLVPHGLLG-PG-PIANGFPPGGPGGPKGMQHFPPGPGG 649
           P   P  + ++  +  D +K      G+ G PG P  NG P  G  G +G+    PG  G
Sbjct: 171 PGL-PGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTP--GQTGARGL----PGERG 223

Query: 650 PM--PGPHG--------GPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPG 699
            +  PGP G        GP GP GP  +G   PP  G P   GP   +      G  GP 
Sbjct: 224 RVGAPGPAGARGSDGSVGPVGPAGP--IGSAGPP--GFPGAPGPKGEIGAVGNAGPAGPA 279

Query: 700 PGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG-------------GGMV 746
                 G  G  G   PP  P   G  G +   G P   G PG              G  
Sbjct: 280 GPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGAT 339

Query: 747 GGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMG----SGHRPHEGPGGSMGGGGGHRP--- 799
           G  G     GP G  G  SG++   G  G  G    SG     GP G  G  G   P   
Sbjct: 340 GARGLVGEPGPAGSKG-ESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGL 398

Query: 800 HEGPGG-GISGGSGHRPHEGPGGGMGAGG--GHRPHEGPGGSMGGSG--GHRPHEG-PGH 853
              PG  G+ G  G     GP G  GA G  G R   G  G  G  G  G R   G PG+
Sbjct: 399 RGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGN 458

Query: 854 GGPHGHR-PHDVPGHRGHDHRGP-PPHEHRGHDG----PG-HGGGGHRGHDGGHSHGG 904
            GP G   P  +PG  G    GP  P   RG  G    PG  G  G  G +G   H G
Sbjct: 459 IGPAGKEGPVGLPGIDGRP--GPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAG 514



 Score = 96.3 bits (238), Expect = 1e-19
 Identities = 133/454 (29%), Positives = 158/454 (34%), Gaps = 99/454 (21%)

Query: 541 GSGGS-----PDGAGGSKLPPVLANLMGSMG-----AGKGPQGPGG--GGINVQEILTSI 588
           GS GS     P G  GS  PP      G  G        GP GP G  G + +  +   +
Sbjct: 235 GSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPV 294

Query: 589 MGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLGP----GPIANGFPPG--------GPGG 636
              P  +P    L     +  +  +    GL GP    GP+      G        GP G
Sbjct: 295 --GPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAG 352

Query: 637 PKGMQ--HFPPGPGGPM--PGPHG-----GPGGPVGPRLLGPPPPP--RGGDPFWDGPGD 685
            KG       PG  GP   PGP G     GP G  G    GPP PP  RG       PG 
Sbjct: 353 SKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSA--GPPGPPGLRGSPGSRGLPGA 410

Query: 686 PMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARG--GRSGGGPPNGRGGPGG 743
             R G M G PG        G  G  G+   P  P   G RG  G  G   P G+ GP G
Sbjct: 411 DGRAGVM-GPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVG 469

Query: 744 --------GMVGGGGHRPHEG------PGGGMGN--SSGHRPHEGPGGGMGS----GHRP 783
                   G +G  G R   G      P G  G+   +G + H G  G  G+    G+  
Sbjct: 470 LPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNG 529

Query: 784 HEGPGGSMG--GGGGHRPHEGPGG--------------------------GISGGSGHRP 815
            +GP G  G  GG G +   GP G                          G+ G +G R 
Sbjct: 530 AQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRG 589

Query: 816 HEGPGGGMGAGG-----GHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGH 870
             GP G  GA G     G R   GP G  G  G        G  GP G  P  +PG RG 
Sbjct: 590 ERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSG--PSGLPGERG- 646

Query: 871 DHRGPPPHEHRGHDGPGHGGGGHRGHDGGHSHGG 904
              G P  +    +    G  G+ G DG     G
Sbjct: 647 -AAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPG 679



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 90/249 (36%), Positives = 104/249 (41%), Gaps = 38/249 (15%)

Query: 631 PGGPGGPKGMQHFPPGPGGPMPGPHG--GPGGPVGPRLLGPPPPPRGGDPF---WDGPGD 685
           P G  GP+G +  PPGP    PG  G  GP GP GP   GPP PP  G  F   +DG G 
Sbjct: 34  PAGDRGPRG-ERGPPGP----PGRDGEDGPTGPPGPP--GPPGPPGLGGNFAAQYDGKGV 86

Query: 686 PMRGGPM-----RGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGG 740
            +  GPM     RG PG    P  +G  G  G    P  P   G  G R   GPP G+ G
Sbjct: 87  GLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGE---PGEPGQTGPAGARGPAGPP-GKAG 142

Query: 741 PGG--GMVGGGGHRPHEGPGG--------GMGNSSGHRPHEGPGGGMGSGHRPH-EGPGG 789
             G  G  G  G R   GP G        G+    G R H G  G  G    P  +G  G
Sbjct: 143 EDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPG 202

Query: 790 SMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHE 849
           + G  G   P +    G+ G  G     GP G  G+ G   P  GP G +G +G   P  
Sbjct: 203 APGENG--TPGQTGARGLPGERGRVGAPGPAGARGSDGSVGP-VGPAGPIGSAG---PPG 256

Query: 850 GPGHGGPHG 858
            PG  GP G
Sbjct: 257 FPGAPGPKG 265



 Score = 88.6 bits (218), Expect = 3e-17
 Identities = 105/337 (31%), Positives = 120/337 (35%), Gaps = 57/337 (16%)

Query: 620 LGPGPIANGFPPGGPG-----GPKGMQHFPPGPGGP-MPGPHG--GPGGPVGPRLLG--P 669
           LGPGP+    P G PG     GP+G Q     PG P   GP G  GP GP G       P
Sbjct: 88  LGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHP 147

Query: 670 PPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGR 729
             P R G+    GP    RG P  G PG       RG  G  G +  P  P  +G  G  
Sbjct: 148 GKPGRPGERGVVGP-QGARGFP--GTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAP 204

Query: 730 SGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRP----HE 785
              G P   G    G+ G  G     GP G  G+     P  GP G +GS   P      
Sbjct: 205 GENGTPGQTG--ARGLPGERGRVGAPGPAGARGSDGSVGP-VGPAGPIGSAGPPGFPGAP 261

Query: 786 GPGGSMGGGGGHRPHEGPGG--------GISGGSGHRPHEGPGGGMGAGG---------- 827
           GP G +G  G   P  GP G        G+SG  G   + G  G  GA G          
Sbjct: 262 GPKGEIGAVGNAGP-AGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGA 320

Query: 828 ----GHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHR----------PHDVPGHRGHDHR 873
               G R   GP G+ G +G       PG  G  G            P   PG  G + +
Sbjct: 321 PGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGK 380

Query: 874 GPPPHEHRGHDGPG----HGGGGHRGHDGGHSHGGDM 906
             P  E      PG     G  G RG  G     G M
Sbjct: 381 RGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVM 417



 Score = 87.8 bits (216), Expect = 4e-17
 Identities = 89/264 (33%), Positives = 106/264 (40%), Gaps = 44/264 (16%)

Query: 623 GPIANGFPPGGPGGPKGMQHFPPGPGGPMPGPHGGPGGPVGP---RLLGPPPPPRG---- 675
           GP     PPG PG        PPG GG     + G G  +GP    L+GP  PP      
Sbjct: 57  GPTGPPGPPGPPG--------PPGLGGNFAAQYDGKGVGLGPGPMGLMGPRGPPGAAGAP 108

Query: 676 GDPFWDGP-GDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGP 734
           G   + GP G+P  G P + GP    GP   G  G+ G +  P  P   G  G R   GP
Sbjct: 109 GPQGFQGPAGEP--GEPGQTGPAGARGP--AGPPGKAGEDGHPGKP---GRPGERGVVGP 161

Query: 735 PNGRGGPG-GGMVGGGGHRPHEGPGG--------GMGNSSGHRPHEGPGGGMGSGHRPHE 785
              RG PG  G+ G  G R H G  G        G+    G     G  G  G+   P E
Sbjct: 162 QGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGE 221

Query: 786 -------GPGGSMGGGGGHRPHEGPGG--GISGGSGHRPHEGPGGGMGAGGGHRP--HEG 834
                  GP G+ G  G   P  GP G  G +G  G     GP G +GA G   P    G
Sbjct: 222 RGRVGAPGPAGARGSDGSVGP-VGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAG 280

Query: 835 PGGSMGGSGGHRPHEGPGHGGPHG 858
           P G +G  G   P   PG+ G +G
Sbjct: 281 PRGEVGLPGLSGPVGPPGNPGANG 304



 Score = 71.2 bits (173), Expect = 4e-12
 Identities = 74/221 (33%), Positives = 86/221 (38%), Gaps = 39/221 (17%)

Query: 692 MRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGH 751
           +R GP    GP    RG RG     PP PP R    G +G  PP   G PG   +GG   
Sbjct: 30  VRKGPAGDRGP----RGERG-----PPGPPGRDGEDGPTG--PPGPPGPPGPPGLGGNFA 78

Query: 752 RPHEGPGGGMG-NSSGHRPHEGPGGGMGS-GHRPHEGPGGSMG--GGGGHRPHEGPGG-- 805
             ++G G G+G    G     GP G  G+ G +  +GP G  G  G  G     GP G  
Sbjct: 79  AQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPP 138

Query: 806 GISGGSGH-----RPHE----GPGGGMGAGG-----------GHRPHEGPGGSMGGSGGH 845
           G +G  GH     RP E    GP G  G  G           GH   +G  G  G  G  
Sbjct: 139 GKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVK 198

Query: 846 RPHEGPGHGGPHGHR-PHDVPGHRGHDHRGPPPHEHRGHDG 885
                PG  G  G      +PG RG     P P   RG DG
Sbjct: 199 GEPGAPGENGTPGQTGARGLPGERGR-VGAPGPAGARGSDG 238



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 60/191 (31%), Positives = 71/191 (37%), Gaps = 21/191 (10%)

Query: 530  ETPYVETLEPGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGG----GINVQEIL 585
            E  Y   + P G+ G+P G  G   P       G  G   GP GP G     G +  + +
Sbjct: 947  ERGYPGNIGPVGAAGAP-GPHGPVGPAGKHGNRGETGPS-GPVGPAGAVGPRGPSGPQGI 1004

Query: 586  TSIMGSPNSHPSEEL--LKQPDYSDKIKQMLVPHGLLG-PGPIANGFP--PGGPGGPKGM 640
                G P       L  LK  +    +  +   HG  G PG +    P  P GP GP G 
Sbjct: 1005 RGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGK 1064

Query: 641  QHFPPGPG--GPM----PGPHGGPGGPVGPRLLGPPPPP--RGGDPFWDGPGDPMRGGPM 692
                  PG  GP     P  H GP GP GP   GPP PP   GG   +   GD  R    
Sbjct: 1065 DGRTGHPGTVGPAGIRGPQGHQGPAGPPGPP--GPPGPPGVSGGGYDFGYDGDFYRADQP 1122

Query: 693  RGGPGPGPGPY 703
            R  P   P  Y
Sbjct: 1123 RSAPSLRPKDY 1133



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 45/137 (32%), Positives = 51/137 (37%), Gaps = 15/137 (10%)

Query: 771 EGPGGGMGS-GHRPHEGPGGSMGGGGGHRPHEGPGG-GISGGSGHRPHEGPGGGMGAGGG 828
           +GP G  G  G R   GP G  G  G   P   PG  G  G  G+   +  G G+G G G
Sbjct: 32  KGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPG 91

Query: 829 HRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGH 888
                GP G  G +G   P    G  G  G      PG  G       P   RG  GP  
Sbjct: 92  PMGLMGPRGPPGAAGAPGPQGFQGPAGEPGE-----PGQTG-------PAGARGPAGP-P 138

Query: 889 GGGGHRGHDGGHSHGGD 905
           G  G  GH G     G+
Sbjct: 139 GKAGEDGHPGKPGRPGE 155


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score =  112 bits (280), Expect = 2e-24
 Identities = 136/421 (32%), Positives = 156/421 (37%), Gaps = 86/421 (20%)

Query: 539 PGGSGGS-PDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPS 597
           PG  G S P G  G+K   V++ + G  G  +GP GP G             G P SH  
Sbjct: 541 PGKHGASGPPGNKGAKGDMVVSRVKGHKGE-RGPDGPPG-----------FPGQPGSHGR 588

Query: 598 EELLKQP-------DYSDKIKQMLVPHGLLGPGPIANGFPPG--GPGGPKGMQHFPPGPG 648
           +    +        D+ D       P G   PGP+    PPG  GP GP G+    PGP 
Sbjct: 589 DGHAGEKGDPGPPGDHEDA-----TPGGKGFPGPLG---PPGKAGPVGPPGLGF--PGP- 637

Query: 649 GPMPGPHGGPGGPVGPRLLGPPP---------------PPRGGDPFWDGPGDPMRGGPMR 693
              PG  G PG P  P + GP                 P R G P +DGP  P      +
Sbjct: 638 ---PGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQ 694

Query: 694 GGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARG--------GRSGGGPPNGRGGPG-GG 744
           G PG      H+GR G  G    P PP FRG  G        G S  GPP   G PG  G
Sbjct: 695 GAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNG 754

Query: 745 MVG--GGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMG--GGGGHRPH 800
             G  G     H GP G  G  SG    +GP G  G      EGP G  G  G  G +  
Sbjct: 755 QKGIPGDPAFGHLGPPGKRG-LSGVPGIKGPRGDPGCPGA--EGPAGIPGFLGLKGPKGR 811

Query: 801 EGPGG--GISGGSGHRPHEG-------------PGGGMGAGGGHRPHE-GPGGSMGGSGG 844
           EG  G  G+ G  GH    G             PG     GG  +P + GP G  G  G 
Sbjct: 812 EGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGL 871

Query: 845 HRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGG-GGHRGHDGGHSHG 903
                 PG  GP G     +PG  G D    PP        PG  G  G RG  G     
Sbjct: 872 PGLPGRPGAHGPPG--LPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCP 929

Query: 904 G 904
           G
Sbjct: 930 G 930



 Score = 97.8 bits (242), Expect = 4e-20
 Identities = 139/447 (31%), Positives = 155/447 (34%), Gaps = 95/447 (21%)

Query: 510  EPYEPIPPKLIPLD-----EECSMDETPYVETLEPGGSGGSPD-----GAGGSKLPPVLA 559
            EP  P PP    +D     +    D   +     P G  GSP      GA G +  P + 
Sbjct: 1052 EPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQ 1111

Query: 560  NLMGSMG-----AGKGPQG-PGGGGINVQEILTSIMGSPNSH--------PSEELLKQPD 605
               GS G        GP G PG  G+         MG P           P    +K P 
Sbjct: 1112 GPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPS 1171

Query: 606  YSDKIKQMLVPHGLLGPGPI--ANGFPPGGPGGP------KGMQHFPPGPGGPMPGPHGG 657
             S  +  +   HGL G      A+G    GP GP      KG +  P  PG   PGP G 
Sbjct: 1172 GSPGLNGL---HGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGK 1228

Query: 658  PGGPVGPRLLGPPPP-----------PRGGDPFWDGPGDPMRGGPMRGGPGPG--PGPYH 704
             G P  P   GPP P           P  G P   GP  P   GP RG PGP   PG   
Sbjct: 1229 KGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGP--DGP-RGAPGPPGLPGSVD 1285

Query: 705  RGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG-GGMVGGGGHRPHEGPGGGMGN 763
              RG  G    P PP             GPP   G PG  G  G  G    +GP G  G 
Sbjct: 1286 LLRGEPGDCGLPGPP-------------GPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGP 1332

Query: 764  SSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPG-----------GGISGGSG 812
                 PH  PG     G +   GP G  G  G   P   PG            G+ G  G
Sbjct: 1333 QG---PHGFPG---PPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPG 1386

Query: 813  HRPHEGPGGGMGAGGGHRPHEGPG--GSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGH 870
             R   GP G MG  G   P  GPG  G  G  G       PG  GP G +     G  G 
Sbjct: 1387 MR---GPEGAMGLPGMRGP-SGPGCKGEPGLDGRRGVDGVPGSPGPPGRK-----GDTGE 1437

Query: 871  D--HRGPPPHEHRGHDGPGHGGGGHRG 895
            D    GP P    G  GP   G G+ G
Sbjct: 1438 DGYPGGPGPPGPIGDPGPKGFGPGYLG 1464



 Score = 96.7 bits (239), Expect = 9e-20
 Identities = 130/433 (30%), Positives = 146/433 (33%), Gaps = 89/433 (20%)

Query: 539  PGGSGGSPDGAGGSKLPPVLA--NLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHP 596
            P G  G P   G + +P  L      G  G    P  PG  G + +     I G P    
Sbjct: 784  PRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGL-- 841

Query: 597  SEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGPHG 656
                   P Y         P G   PG +       GP GP GM+  P  PG   PG HG
Sbjct: 842  -------PGYPGSPG---APGGKGQPGDV-------GPPGPAGMKGLPGLPG--RPGAHG 882

Query: 657  GPG-----GPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRG 711
             PG     GP G   L  PP P+G       PG P      RG PG    P  +G  G  
Sbjct: 883  PPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGE----RGKPGAEGCPGAKGEPGEK 938

Query: 712  GNEPPPPPPPFRGARG-----------------GRSGG-GPPNGRGGPGG-GMVGGGGHR 752
            G    P     RGA+G                 G  G  GPP   G PG  G  G  G +
Sbjct: 939  GMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQ 998

Query: 753  PHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMG-----------GGGGHRPHE 801
               G  G  G    HR   G  G  G    P  GP GS G           G  G     
Sbjct: 999  GRRGEPGRYGPPGFHRGEPGEKGQPGPPGPP--GPPGSTGLRGFIGFPGLPGDQGEPGSP 1056

Query: 802  GPGG--GISGGSGHR-------PHEGPGGGMGAGG--GHRPHEGPGGSMGGSGGHRPHEG 850
            GP G  GI G  G +        H GP G  G  G  G   H G  G  G  G   P   
Sbjct: 1057 GPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGS 1116

Query: 851  PGHGGPHGHR-------PHDVPGHRGH--DHRGPPPHEHRGHDG-PG----HGGGGHRGH 896
            PG  GP G          H +PG RG   +   P P   +G  G PG     G  G  G 
Sbjct: 1117 PGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGL 1176

Query: 897  DGGHSHGGDMSNR 909
            +G H   G    +
Sbjct: 1177 NGLHGLKGQKGTK 1189



 Score = 94.4 bits (233), Expect = 5e-19
 Identities = 139/470 (29%), Positives = 161/470 (34%), Gaps = 112/470 (23%)

Query: 539 PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
           PG  G S  GA G K  P      G  G+   P  PG  G         ++G P      
Sbjct: 287 PGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGE------LGLVGDPGLFG-- 338

Query: 599 ELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHF----PPGPGG----- 649
             L  P      +    P G+L   P+    PPG PG P          PPGP G     
Sbjct: 339 --LIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRP 396

Query: 650 -----PMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDP----MRGGP-MRGGPG-- 697
                 M GP G  G P  P L G    P   D     PG P    + G P ++G PG  
Sbjct: 397 GEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSS 456

Query: 698 --------PGP--------GPYHRGRGGRGGNE-----------PPPPP--PPFRGARG- 727
                   PGP         P  RG  G  GNE           PP PP  P  +G++G 
Sbjct: 457 VIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGD 516

Query: 728 -------GRSGG-GPPNGRGGPG-GGMVGGGGHRPHEGPGGGM--GNSSGHRPHEGPGGG 776
                  G  G  GPP   G PG  G  G  G   ++G  G M      GH+   GP G 
Sbjct: 517 LGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGP 576

Query: 777 MGSGHRP-------HEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAG--- 826
            G   +P       H G  G  G  G H      G G  G  G     GP G  G G   
Sbjct: 577 PGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPG 636

Query: 827 -GGHRPHEGPGGSMG--GSGGHRPHEG---------------PGHGGPHGHR----PHDV 864
             G R H G  G  G  G  G +  +G               PG  GP G +    P   
Sbjct: 637 PPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGA 696

Query: 865 PGHRGHD-HRGPPPHEHRGHDGPGH--GGGGHRGHDGGHSHGGDMSNRPV 911
           PG  G D H+G P     G  G     G  G RG  G    GG+  + PV
Sbjct: 697 PGLSGSDGHKGRP-----GTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPV 741



 Score = 92.0 bits (227), Expect = 2e-18
 Identities = 96/285 (33%), Positives = 111/285 (38%), Gaps = 44/285 (15%)

Query: 622  PGPIANGFPPGGPGGP--KGMQHFPPGPGGPMPGPHGGPGGPVGPRLLGPP----PPPRG 675
            PG      PPG PG P   G++ F   PG  +PG  G PG P  P   G      P    
Sbjct: 1017 PGEKGQPGPPGPPGPPGSTGLRGFIGFPG--LPGDQGEPGSPGPPGFSGIDGARGPKGNK 1074

Query: 676  GDPFWD-GPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGP 734
            GDP    GP  P      +G PG    P H G  G  G       P  +G RG     GP
Sbjct: 1075 GDPASHFGPPGP------KGEPGSPGCPGHFGASGEQGL------PGIQGPRGSPGRPGP 1122

Query: 735  PNGRGGPG-------GGMVGGGGHRPHEGPGGGMGNSSGHRPH--EGPGGGMG-SGHRPH 784
            P   G PG        G+ G  G     GP G  G+     P   +GP G  G +G    
Sbjct: 1123 PGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGL 1182

Query: 785  EGPGGSMGGGGGHRPHEGPGG--GISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGS 842
            +G  G+ G  G H    GP G  GI G  G R   G  G   +  G R  +GP G  G S
Sbjct: 1183 KGQKGTKGASGLH--DVGPPGPVGIPGLKGERGDPGSPGI--SPPGPRGKKGPPGPPGSS 1238

Query: 843  GGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPP-PHEHRGHDGP 886
            G       PG  G  G  P D+P       +GPP P   RG  GP
Sbjct: 1239 GP------PGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGP 1277



 Score = 90.1 bits (222), Expect = 9e-18
 Identities = 144/423 (34%), Positives = 165/423 (39%), Gaps = 82/423 (19%)

Query: 541  GSGGSPDGAGGSKLP--PVLANLMGSMGAGK-------GPQGPGGG-GINVQEILTSIMG 590
            G  G P   G +++P  P     MG  G G        GP GP G  G+N Q+      G
Sbjct: 704  GHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQK------G 757

Query: 591  SPNSHPSEELLKQPDYSDKIKQMLVPHGLLGPG-----PIANGFPPGGPG-----GPKGM 640
             P   P+   L  P    K     VP G+ GP      P A G P G PG     GPKG 
Sbjct: 758  IPGD-PAFGHLGPPG---KRGLSGVP-GIKGPRGDPGCPGAEG-PAGIPGFLGLKGPKGR 811

Query: 641  QHFPPGPGGPMPGPH----GGPGGPVGPRLLGPPPPPRGGDPFWDG-PGDPMRGGP--MR 693
            +     PG P P  H    G PG P  P L G P  P  G P   G PGD    GP  M+
Sbjct: 812  EGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSP--GAPGGKGQPGDVGPPGPAGMK 869

Query: 694  GGPG-PG-PG----PYHRGRGGRGGNEPPPPPPPFRGARG-----------GRSGG-GPP 735
            G PG PG PG    P   G  G  G++  P PP  +G RG           G+ G  G P
Sbjct: 870  GLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCP 929

Query: 736  NGRGGPG-GGMVGGGGHRPHEGPGGGMG-----------NSSGHRPHEGPGGGMG-SGHR 782
              +G PG  GM G  G R   G  G +G           +  G     GP G  G  G R
Sbjct: 930  GAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGER 989

Query: 783  PHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGG--GHRPHEGPGGSMG 840
              +G  G M G  G     GP G   G  G +   GP G  G  G  G R   G  G  G
Sbjct: 990  GDKGTPG-MQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPG 1048

Query: 841  GSGGHRPHEGPGHGGPHGHRPHDVPGHRGH--DHRGPP-PHEHRGHDG-PGH-GGGGHRG 895
              G       PG  G  G R     G++G    H GPP P    G  G PGH G  G +G
Sbjct: 1049 DQGEPGSPGPPGFSGIDGAR--GPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQG 1106

Query: 896  HDG 898
              G
Sbjct: 1107 LPG 1109



 Score = 71.2 bits (173), Expect = 4e-12
 Identities = 88/278 (31%), Positives = 101/278 (36%), Gaps = 38/278 (13%)

Query: 646 GPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHR 705
           G  GP PGP G P GP+GP L  P P    G+    G   P      +G  GP   P   
Sbjct: 62  GSRGP-PGPPG-PQGPIGP-LGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFP 118

Query: 706 GRGGRGGNEPPPPP---PPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMG 762
           G  G  G+  PP P   P   G  G R   G P GRG      +G GG   H G  G  G
Sbjct: 119 GLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGA-----LGPGGPLGHPGEKGEKG 173

Query: 763 NS----SGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPG-GGISGGSGHRPHE 817
           NS       +  +G  G  G    P     GS G GG   P   PG  G+ G  G     
Sbjct: 174 NSVFILGAVKGIQGDRGDPGLPGLP-----GSWGAGGPAGPTGYPGEPGLVGPPGQPGRP 228

Query: 818 GPGGGMGAG-GGHRPHEGPGGSMGGSGGHRPHEGPG---HGGPHGHRPHDVPGHRGHDHR 873
           G  G  G G  G     G  G  G  G     E P    + G  G +   +PG  G    
Sbjct: 229 GLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIK--GIPGMVGL--- 283

Query: 874 GPPPHEHRGHDGPGHGG-------GGHRGHDGGHSHGG 904
            P P   +G  G G  G        G RG  G +   G
Sbjct: 284 -PGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPG 320



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 85/257 (33%), Positives = 92/257 (35%), Gaps = 59/257 (22%)

Query: 630 PPGGPGGPKGMQHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRG 689
           P  G  GP G    PPGP GP+ GP G PG P+G  L G                     
Sbjct: 59  PEKGSRGPPG----PPGPQGPI-GPLGAPG-PIG--LSGEKG------------------ 92

Query: 690 GPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGG 749
             MRG  GP       G  G  G++ P   P F G  G     GPP  RG P  GM G  
Sbjct: 93  --MRGDRGPP------GAAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKP--GMSGHN 142

Query: 750 GHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISG 809
           G R   G  GG G         GPGG +G     H G  G  G         G   GI G
Sbjct: 143 GSRGDPGFPGGRGAL-------GPGGPLG-----HPGEKGEKGNSVFIL---GAVKGIQG 187

Query: 810 GSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRG 869
             G     G  G  GAGG      GP G  G  G   P   PG  G  G+    V G  G
Sbjct: 188 DRGDPGLPGLPGSWGAGG----PAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMG 243

Query: 870 HDHRGPPPHEHRGHDGP 886
                P     +G  GP
Sbjct: 244 ----DPGEVGQQGSPGP 256



 Score = 63.9 bits (154), Expect = 7e-10
 Identities = 95/300 (31%), Positives = 109/300 (36%), Gaps = 58/300 (19%)

Query: 616 PHGLLG-PGPIA---------NGFPPGGPG-----GPKGMQHFPPGPGGPMPGPHGGPGG 660
           P G LG PGPI          +  PPG  G     GP G+  FP   G  +PG H GP G
Sbjct: 75  PIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGLDG--IPG-HPGPPG 131

Query: 661 PVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPP 720
           P G       P   G +     PG P  GG  RG  GPG    H G  G  GN       
Sbjct: 132 PRG------KPGMSGHNGSRGDPGFP--GG--RGALGPGGPLGHPGEKGEKGNS-VFILG 180

Query: 721 PFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSG 780
             +G +G R   G P   G  G G  G  G   + G  G +G   G     G  G  G G
Sbjct: 181 AVKGIQGDRGDPGLPGLPGSWGAG--GPAGPTGYPGEPGLVG-PPGQPGRPGLKGNPGVG 237

Query: 781 HRPHEGPGGSMGGGGGHRPH---EGPG-------GGISGGSGHRPHEGPGGGMGAGG-GH 829
            +   G  G +G  G   P    E P         GI G  G     GP G  G  G G 
Sbjct: 238 VKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGA 297

Query: 830 RPHEGPGGSMGGSGGHRPHEGPGHGGPHGH-------------RPHDVPGHRGHDHRGPP 876
           +  +G  G  G  G    +  PG  G  G               P   PG+RGH   GPP
Sbjct: 298 KGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHP--GPP 355



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 74/229 (32%), Positives = 81/229 (35%), Gaps = 78/229 (34%)

Query: 539  PGGSGG-SPDGAGGSKLPPVLAN----LMGSMG--AGKGPQGPGGGGINVQEILTSIMGS 591
            PG  G   PDG  G+  PP L      L G  G     GP GP G               
Sbjct: 1260 PGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPG--------------- 1304

Query: 592  PNSHPSEELLKQPDYSDKIKQMLVPHGLLGP-GPIANGFPPGGPGGPKGMQHFPPGPGGP 650
            P   P  +     D  D  K    P G  GP GP  +GFP  GP G KG+   PPG  GP
Sbjct: 1305 PPGPPGYKGFPGCDGKDGQKG---PVGFPGPQGP--HGFP--GPPGEKGLPG-PPGRKGP 1356

Query: 651  --MPGPHGGPG---------------------GPVG----PRLLGPPPPPRGGDPFWDG- 682
              +PGP G PG                     GP G    P + GP  P   G+P  DG 
Sbjct: 1357 TGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGR 1416

Query: 683  ------PGDP-------------MRGGPMRGGPGPGPGPYHRGRGGRGG 712
                  PG P               GGP   GP   PGP   G G  GG
Sbjct: 1417 RGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGFGPGYLGG 1465


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score =  111 bits (277), Expect = 4e-24
 Identities = 152/473 (32%), Positives = 181/473 (38%), Gaps = 78/473 (16%)

Query: 470  PSPLVTPGSNSQERYIQAEREKGILQELFL----NKESPHEPDPEPYEPIPPKLIPLDEE 525
            P P   PG   Q   I     KG + ++        E P  P   P +P  P L P  + 
Sbjct: 1005 PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGL-PGQKG 1063

Query: 526  CSMDETPYVETL----------EPG--GSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQG 573
               D  P + ++          EPG  G  G+P G  GS   P L  L G+ GA KG  G
Sbjct: 1064 DKGD--PGISSIGLPGLPGPKGEPGLPGYPGNP-GIKGSVGDPGLPGLPGTPGA-KGQPG 1119

Query: 574  ----------PGGGGINVQEILTSIMGSPN-----SHPSEELLKQPDYSDKIKQMLVP-- 616
                      PG  GI+       + G P       HP +     P    K  Q  +P  
Sbjct: 1120 LPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQP--GPPGEKGKPGQDGIPGP 1177

Query: 617  ---HGLLGPGPIANGFPPGGPG--GPKGMQHFPPGPGGP-MPGPHGGPGGPVGPRLLGPP 670
                G  G     N  PPG PG  G KG    P  PG P +PGP G PG    P + GPP
Sbjct: 1178 AGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPP 1237

Query: 671  PPPRGGDPFWDGP-GDPMRGGP-----MRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRG 724
             PP    P  +GP G+P   GP      +G PGP   P   G GG  G +  P  P   G
Sbjct: 1238 GPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPG 1297

Query: 725  ARGGRSGGGPPNGRGGPG-GGMVGGGGHRPHEGPGG--GMGNSSGHRPHEGPGGGMGSGH 781
              G +   GPP  +G PG  G+ G  G     G  G  GM   SG     GP G  G   
Sbjct: 1298 LPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIG 1357

Query: 782  RPHEGPGGSMGGGGGHRPHEGPGG--GISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGS- 838
             P  GP G  G  G     +G  G  GI G  G +   GP G  G  G   P   PG + 
Sbjct: 1358 PP--GPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNG 1415

Query: 839  ---MGGSGGHRPHEG-PGHGGPHGHRPHDVPGHRGHDHRGPP-PHEHRGHDGP 886
                 G+GG +   G PG            PG RG D  GPP P   +G  GP
Sbjct: 1416 LPGFDGAGGRKGDPGLPGQ-----------PGTRGLD--GPPGPDGLQGPPGP 1455



 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 135/430 (31%), Positives = 152/430 (35%), Gaps = 75/430 (17%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGP-------------GGGGINVQEIL 585
            P GS G P  AG S  P      MG MG   GP GP             G  G+  Q  L
Sbjct: 876  PPGSPGLPGKAGASGFPGTKGE-MGMMGP-PGPPGPLGIPGRSGVPGLKGDDGLQGQPGL 933

Query: 586  TSIMGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPG--GPKGMQHF 643
                G   S     L   P   D       P+ L   G       PG PG  GPKG Q  
Sbjct: 934  PGPTGEKGSKGEPGLPGPPGPMD-------PNLLGSKGEKGEPGLPGIPGVSGPKGYQGL 986

Query: 644  PPGPGGP----------MPGPHGGPGGPVGPRLLGPP-----------PPPRG--GDPFW 680
            P  PG P           PGP G PG P  P L+GPP           P P+G  G P  
Sbjct: 987  PGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGP 1046

Query: 681  DG-PGDPMRGG-PMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGR 738
             G PG P   G P + G    PG    G  G  G +  P  P + G  G +   G P   
Sbjct: 1047 SGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLP 1106

Query: 739  GGPGG----GMVGGGGHRPHEGPGG--GMGNSSGHRPHEG-PGGGMGSGHRPHEGPGGSM 791
            G PG     G  G  G     GP G  G+    G+    G PG   G GH    GP G  
Sbjct: 1107 GLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEK 1166

Query: 792  G--------GGGGHRPHEGPGG-------GISGGSGHRPHEGPGGGMGAGGGHRPHEGPG 836
            G        G  G +   G  G       G+ G SG +   G  G  G  G   P +G  
Sbjct: 1167 GKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGP-KGEP 1225

Query: 837  GSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPG--HGGGGHR 894
            G  G  G   P   PG  GP    P   PG +G   R P      G +GP    G GG +
Sbjct: 1226 GFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGR-PGFQGLPGPEGPPGLPGNGGIK 1284

Query: 895  GHDGGHSHGG 904
            G  G     G
Sbjct: 1285 GEKGNPGQPG 1294



 Score = 98.2 bits (243), Expect = 3e-20
 Identities = 127/372 (34%), Positives = 145/372 (38%), Gaps = 63/372 (16%)

Query: 539 PGGSG--GSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHP 596
           PG  G  GS    G     P +    G +G+   P  PG  G   Q+ L  + G P   P
Sbjct: 535 PGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPG-PKGEP 593

Query: 597 SEELLKQPDYSDKIKQMLVPHGLLGP-GPIANGFPPGGPGGPKGMQHFPPGPGGP-MPGP 654
                K          +    G +GP GP   GF P GP G KG+Q     PG P +PGP
Sbjct: 594 GGITFKGERGPPGNPGLPGLPGNIGPMGP--PGFGPPGPVGEKGIQGVAGNPGQPGIPGP 651

Query: 655 HGGPG------------------GPVG----PRLLGPPP----PPRGGDPFWDGPGDPMR 688
            G PG                  G VG    P L G P     P   G+P   G G P  
Sbjct: 652 KGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP 711

Query: 689 GGPMRGGPG-PGPGPYHRGRGGRGGNEPPPPPPPFRGARG--GRSGGGPPNGRGGPG-GG 744
            GP +G PG PGP P   G  GR G E PP PP F G +G  G +  GPP   G PG  G
Sbjct: 712 PGP-KGFPGIPGP-PGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG 769

Query: 745 MVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEG-- 802
            +G  G R   GP              GP G  G    P  GP G +G  G   P     
Sbjct: 770 ALGPKGDRGFPGP-------------PGPPGRTGLDGLP--GPKGDVGPNGQPGPMGPPG 814

Query: 803 -PGGGISGGSGHRPHEGPGGGMGAGG--GHRPHEGPGG-SMGGSGGHRPHEG-PGHGGPH 857
            PG G+ G  G     GP G  G  G  G +   GP G  + G  G R   G PG  GP 
Sbjct: 815 LPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPI 874

Query: 858 GHRPHDVPGHRG 869
           G  P   PG  G
Sbjct: 875 G--PPGSPGLPG 884



 Score = 96.7 bits (239), Expect = 9e-20
 Identities = 166/530 (31%), Positives = 189/530 (35%), Gaps = 142/530 (26%)

Query: 538  EPGGSG----------GSP--DGAGGSKLPPVLANLMGSMGAG-----------KGPQGP 574
            +PG  G          GSP   GA G   PP    L G  GA             GP GP
Sbjct: 847  DPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGP 906

Query: 575  GGG-GINVQEILTSIMGSPNSHPSEELLKQPDYSDKI--KQMLVPHGLLG-PGPI----- 625
             G  GI  +       G P     + L  QP        K      GL G PGP+     
Sbjct: 907  PGPLGIPGRS------GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960

Query: 626  ----ANGFP--PGGPG--GPKGMQHFPPGPGGP----------MPGPHGGPGGPVGPRLL 667
                  G P  PG PG  GPKG Q  P  PG P           PGP G PG P  P L+
Sbjct: 961  GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI 1020

Query: 668  GPP-----------PPPRG--------------------------GDPFWDGPGDPMRGG 690
            GPP           P P+G                          GDP     G P   G
Sbjct: 1021 GPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG 1080

Query: 691  PMRGGPG-PG-PG----------PYHRGRGGRGGNEPPPPPPPFRGARG--GRSG-GGPP 735
            P +G PG PG PG          P   G  G  G +  P  P F G  G  G  G  GPP
Sbjct: 1081 P-KGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPP 1139

Query: 736  NGRGGPG-GGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRP---HEGPGGSM 791
               G PG  G VGGGGH    GP G  G   G     GP G  G   +P   + GP G  
Sbjct: 1140 GNPGLPGEPGPVGGGGHPGQPGPPGEKG-KPGQDGIPGPAGQKGEPGQPGFGNPGPPGLP 1198

Query: 792  GGGGGHRPHEGPGG--GISGGSG-HRPHEGPG--GGMGAGGGHRPHEGPGGSMGGSGGHR 846
            G  G     +G GG  GI G  G   P   PG  G  G  G   P   PG ++ G  G+ 
Sbjct: 1199 GLSG----QKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNP 1254

Query: 847  PHEGP-------GHGGPHGHRPHDVPGHRG-HDHRGPPPHEH-------RGHDGPGHGGG 891
              +GP       G  GP G  P  +PG+ G    +G P           +G  GP  G  
Sbjct: 1255 GPQGPPGRPGFQGLPGPEG--PPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGP-PGLQ 1311

Query: 892  GHRGHDGGHSHGGDMSNRPVCRHFMMKGNCRYENNCA-FYHPGVNGPPLP 940
            G+ G  G +   GD     V     MKG      +      PG+ GPP P
Sbjct: 1312 GNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1361



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 92/274 (33%), Positives = 105/274 (38%), Gaps = 31/274 (11%)

Query: 633 GPGGPKGMQHFPPGPGGP-MPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDG-PGDPMRGG 690
           G  G KG + FP   G P +PG   GP GP GPR          G    DG PG P   G
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPG-FPGPEGPPGPR----------GQKGDDGIPGPPGPKG 90

Query: 691 PMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG-GGMVGGG 749
            +RG PG    P   G  G  G++  P P    G  G +   G P   G PG  G  G  
Sbjct: 91  -IRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPP 149

Query: 750 GHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISG 809
           G    +G  G +  SS   P   PG     G +   GP G  G  G   P      G+ G
Sbjct: 150 GIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGP-----PGLMG 204

Query: 810 GSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRG 869
             G     GP G MG        +GP G  G  G   P   PG       RP DV   +G
Sbjct: 205 PPGPPGLPGPKGNMGLN-----FQGPKGEKGEQGLQGPPGPPGQISEQ-KRPIDVEFQKG 258

Query: 870 HD----HRGPP-PHEHRGHDGPGHGGGGHRGHDG 898
                  RGPP P   RG  GP  G  G +G  G
Sbjct: 259 DQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQG 292



 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 132/435 (30%), Positives = 159/435 (36%), Gaps = 80/435 (18%)

Query: 539 PGGSG-GSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQ-----EILTSIMGSP 592
           PG  G   P G  G   PP    LMG  G    P   G  G+N Q     +    + G P
Sbjct: 179 PGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPP 238

Query: 593 NSHPSEELLKQP-DYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGM--QHFPPGPGG 649
                    K+P D   +     +P     PGP     PPG PGG KG   +   PG  G
Sbjct: 239 GPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRG 298

Query: 650 PMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGP--MRGGPGPGPGP----- 702
             PG  G  G P      G P  P  GDP +  PG+P R G    +G  GP PGP     
Sbjct: 299 -KPGKDGENGQP------GIPGLP--GDPGY--PGEPGRDGEKGQKGDTGP-PGPPGLVI 346

Query: 703 YHRGRG---GRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGG---------GMVGGGG 750
              G G   G  GN   P  P  +G RG     GPP   G PG          G  G  G
Sbjct: 347 PRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERG 406

Query: 751 HRPHEGPGG-------GMGNSSGHRPHEGPGGGMGSGHRPHE--------GPGGSMGGGG 795
            +  EGP G       G+    G     GP G  G    P +        GP GS G  G
Sbjct: 407 QKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKG 466

Query: 796 --GHRPHEGP---------GGGISGGSGHRPHEGPGGGMGAGG--GHRPHEGPGGSMGGS 842
             G +  +G          G GISG  G     G  G  G+ G  G +  +G  G+ G  
Sbjct: 467 LQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPK 526

Query: 843 GGHRPHEGPGHGGPHGHR--PHDV---PGHRGH--DHRGPPPHEHRGHDG-PGHGG---- 890
           G       PG  G  G +  P D+   PG +G   +   P      G  G PG  G    
Sbjct: 527 GLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGL 586

Query: 891 GGHRGHDGGHSHGGD 905
            G +G  GG +  G+
Sbjct: 587 PGPKGEPGGITFKGE 601



 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 101/341 (29%), Positives = 120/341 (35%), Gaps = 66/341 (19%)

Query: 616 PHGLLGPGPIANGFPPGGPG--GPKGMQHFPPGPGGPMPGPHG-----------GPGGPV 662
           P GL GP   A   PPG PG  G +G +     PG  +PGP G           GP GP 
Sbjct: 381 PPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA 440

Query: 663 GPRL--------LGPPPPPRG----------------GDPFWDGPGDPMRGGPMRGG-PG 697
           GP +         GPP PP                  GD  ++  G  + G P + G PG
Sbjct: 441 GPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPG 500

Query: 698 -PGPG-----PYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGG-----GMV 746
            PGP      P  +G  G+ G   P   P   GA G     G P  +G PG      GM 
Sbjct: 501 LPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPG---APGFPGSKGEPGDILTFPGMK 557

Query: 747 GGGGHRPHEGPGG--GMGNSSGH-------RPHEGPGGGMGSGHRPHEGPGGSMGGGGGH 797
           G  G     G  G  G+  + G         P   PGG    G R   G  G  G  G  
Sbjct: 558 GDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNI 617

Query: 798 RPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPH 857
            P   PG G  G  G +  +G  G  G  G   P   PG ++   G       PG  G  
Sbjct: 618 GPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDV 677

Query: 858 GHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDG 898
           G     +PG  G   +   P        PG  G G  G  G
Sbjct: 678 G-----LPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPG 713



 Score = 77.4 bits (189), Expect = 6e-14
 Identities = 109/354 (30%), Positives = 125/354 (35%), Gaps = 71/354 (20%)

Query: 616 PHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGP-------MPGP------------HG 656
           P G  G   I     P G  GP G+  FP  PG P        PGP             G
Sbjct: 73  PRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERG 132

Query: 657 GPGGPVGPRLLGPPPPP----RGGDP------FWDGP-GDPMRGGP--MRGGPGPGPGPY 703
            PG P  P L GPP PP      G+P         GP G+P   GP  ++G PGP   P 
Sbjct: 133 FPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPG 192

Query: 704 HRGRGGRGGNEPPPPPPPFRGARG--GRSGGGPPNGRG-----GPGG------------- 743
             G  G  G   PP PP   G +G  G +  GP   +G     GP G             
Sbjct: 193 PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252

Query: 744 -----GMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGS-GHRPHEGPGGSMGGGGGH 797
                G  G  G R   GP G  G        +G  G  G  G R   G  G  G  G  
Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312

Query: 798 RPHEGPG-GGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGP 856
                PG  G  G  G +  +G  G  G  G   P  G G ++G  G       PG  G 
Sbjct: 313 GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372

Query: 857 HG----HRPHDVPGHRGHDHRGPP-----PHE--HRGHDG-PGHGGGGHRGHDG 898
            G      P  +PG  G    GPP     P E   +G +G PG    G  G DG
Sbjct: 373 RGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG 426



 Score = 77.0 bits (188), Expect = 8e-14
 Identities = 134/459 (29%), Positives = 162/459 (35%), Gaps = 141/459 (30%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMGAG-----KGPQGPGGGGINVQEILTSIMGSPN 593
            PG  G       G   PP L    G++G        GP GP G         T + G P 
Sbjct: 745  PGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGR--------TGLDGLPG 796

Query: 594  SHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPG----GPKGMQHFPPGPGG 649
                             K  + P+G   PGP+    PPG PG    GP G    PPG  G
Sbjct: 797  P----------------KGDVGPNGQ--PGPMG---PPGLPGIGVQGPPG----PPGIPG 831

Query: 650  PM--PGPHGGPG---GPVGPRLLGPPPPPRGGDPFWDG----------PGDPMRGGP--- 691
            P+  PG HG PG    P  P L  P PP   G P   G          PG P + G    
Sbjct: 832  PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGF 891

Query: 692  --------MRGGPGPGPGPYH----------RGRGGRGGNEPPPPPPPFRGARGGRSGGG 733
                    M G PGP PGP            +G  G  G    P P   +G++G     G
Sbjct: 892  PGTKGEMGMMGPPGP-PGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPG 950

Query: 734  PP-----------NGRGGPG-GGMVGGGGHRPHEGPGG--GMGNSSGHRPHEGPGGGMGS 779
            PP             +G PG  G+ G  G + ++G  G  G    SG     GP G  G+
Sbjct: 951  PPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN 1010

Query: 780  GHRPHE----GPGGSMG-----GGGGHRPHEGPGG--GISGGSGHRPHEGPGGGMGAGG- 827
               P +    GP G  G     G  G +  EGP G  G+ G  G     G  G  G  G 
Sbjct: 1011 PGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI 1070

Query: 828  ------------------GHRPHEGPGGSMG--------GSGGHRPHEG-PGHGGPHGHR 860
                              G+  + G  GS+G        G+ G +   G PG  G  G  
Sbjct: 1071 SSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPG-- 1128

Query: 861  PHDVPGHRGHDHRGPPPHEH-RGHDGPGHGGGGHRGHDG 898
                PG +G    GPP +    G  GP  GGGGH G  G
Sbjct: 1129 ---PPGPKGIS--GPPGNPGLPGEPGP-VGGGGHPGQPG 1161



 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 93/305 (30%), Positives = 106/305 (34%), Gaps = 77/305 (25%)

Query: 539  PGGSGGSPDGAG-GSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPS 597
            P G  G P   G G+  PP L  L G  G G  P  PG  G      L    G P  H  
Sbjct: 1177 PAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPG------LPGPKGEPGFHGF 1230

Query: 598  EELLKQPDYSDKIKQMLVPHGLLGP---GPIANGFPPGGPGGPKGMQHFPPGPGGP---- 650
              +   P           P G  GP   GP  N  P G PG P G Q  P GP GP    
Sbjct: 1231 PGVQGPPG----------PPGSPGPALEGPKGNPGPQGPPGRP-GFQGLP-GPEGPPGLP 1278

Query: 651  ----MPGPHGGPGGPVGPRLLG-----PPPPPRG-----------GDPFWDG-PGDPMRG 689
                + G  G PG P  P L G      PP  +G           GDP   G PG P   
Sbjct: 1279 GNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMK 1338

Query: 690  GP--------------MRGGPGPG--PGPYHRGRGGRGGNEPP--PPPPPFRGARGGRSG 731
            GP              + G PGP   PGP  +    +G   PP  P  P  +G  G +  
Sbjct: 1339 GPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGP 1398

Query: 732  GGPPNGRGGPGG-------GMVGGGGHRPHEGPGG-----GMGNSSGHRPHEGPGGGMGS 779
             G P   G PG        G  G GG +   G  G     G+    G    +GP G  G+
Sbjct: 1399 QGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGT 1458

Query: 780  GHRPH 784
                H
Sbjct: 1459 SSVAH 1463


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score =  108 bits (271), Expect = 2e-23
 Identities = 134/411 (32%), Positives = 162/411 (39%), Gaps = 85/411 (20%)

Query: 541  GSGGSPDGAGGSKLPPVLANL--MGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
            GS G P   G    P  L  +   GS+G   GP GP G            +G P  +  E
Sbjct: 874  GSQGLPGFPGARGKPGPLGKVGDKGSIGF-PGPPGPEG--------FPGDIGPPGDNGPE 924

Query: 599  ELLKQPDYSDKIKQMLVPHGLLGP----GPIANGFPPGGPG--GPKGMQHFPPGPG-GPM 651
             +  +P      + +  P G LGP    GP+    PPG PG  G  G + FP  PG   +
Sbjct: 925  GMKGKPG----ARGLPGPRGQLGPEGDEGPMG---PPGAPGLEGQPGRKGFPGRPGLDGV 977

Query: 652  PGPHGGPG--GPVGPR----------------------LLGPP--PPPRG--GDPFWDGP 683
             G  G PG  GPVG +                      ++GPP  P P+G  G P   G 
Sbjct: 978  KGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGG 1037

Query: 684  -GDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG 742
             G P   GP +G PG    P  RG  GR G   P  P   +G+RG +   GPP  +G PG
Sbjct: 1038 MGTPGEPGP-QGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLK---GPPGPQGRPG 1093

Query: 743  -GGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHE----GPGGSMGGGGGH 797
              G  G  G R H G       S G     GP G  G+   P E    GP G +G  G  
Sbjct: 1094 RPGQQGVAGERGHLG-------SRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEM 1146

Query: 798  RPHEGPGG----GISGGSGHRPHEGPGGGMGAGG-----GHRPHEGPGGSMGGSGGHRPH 848
             P   PG     G+ G +G +   GP G  G  G     G    EG  G MG  G     
Sbjct: 1147 GPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDR 1206

Query: 849  EGPGHGGPHGHRPHDVPGHRGHDHRGPP-PHEHRGHDGPGHGGGGHRGHDG 898
              PG  G HG +  +  G  G D  GPP P    G  GP  G  G +G  G
Sbjct: 1207 GDPGPDGEHGEKGQE--GLMGED--GPPGPPGVTGVRGP-EGKSGKQGEKG 1252



 Score =  105 bits (262), Expect = 2e-22
 Identities = 226/816 (27%), Positives = 289/816 (35%), Gaps = 165/816 (20%)

Query: 197  SLRTTAPSHAKFRSTGLELETPSLVPVKKNASTVVVS-DKYNLKPIPLKRQ---SNVAAP 252
            S + TA    K   T     + S+VP+K    T   +   +    +P ++Q   ++   P
Sbjct: 356  SQKITATKIPKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALPTQKQVPPTSRPVP 415

Query: 253  GDATPPAEKKYKPLNTTPNATKEIKVKIIPPQPMEGLGFLDALNSAPVPGIKIKKKKKVL 312
               + PAEK   P+   P   +       PP     L    + +  P+P +   + K  +
Sbjct: 416  ARVSRPAEK---PIQRNPGMPRP------PPPSTRPLPPTTSSSKKPIPTLARTEAK--I 464

Query: 313  SPTAAKPSPFEGKTSTE---PSTAKPSSPEPAPPSEAMDADRPGTPVPPVEVPELMDTAS 369
            +  A+KP+    +TST    P TA  SSP P P S       P T VPP        TA 
Sbjct: 465  TSHASKPA--SARTSTHKPPPFTALSSSPAPTPGS-TRSTRPPATMVPPTSGTSTPRTAP 521

Query: 370  LEPGALDAKPVESPGDPNQLTRKGRKRKSVTWPEEGKLREYFYFELDETERVNVNKIKDF 429
              P    A         ++ ++K   + S   P    LR                     
Sbjct: 522  AVPTPGSAPTGSKKPIGSEASKKAGPKSSPRKPV--PLRP-------------------- 559

Query: 430  GEAAKREILSDRHAFETARRLSHDNMEEKVPWVCPRPLVLPSPLVTPGSNSQERYIQAER 489
            G+AA+   LSD     + R+            + P   +  SP  T  S     ++    
Sbjct: 560  GKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPRPT-SSGYSIFHLAGST 618

Query: 490  EKGILQELFLNKESPHEPDPEPYEPIPPKL-----IPLDEECSMDETPYVETLEPG---- 540
               +L         P  P  +   P PP L     IP          PY     PG    
Sbjct: 619  PFPLLM-------GPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGA 671

Query: 541  -GSGGSP--------DGAGGSKLPPVLANLMGSMGAGKGPQG-PGGGGINVQEILTSIMG 590
             G  G P        DGA G    P L+   G  G  KG +G PG  G   ++      G
Sbjct: 672  KGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGR-KGHKGYPGPAGHPGEQGQPGPEG 730

Query: 591  SPNS--HPSEELLKQP--DYSDKIKQMLVP-HGLLG-PGPIANGFPPGGPG--GPKGMQH 642
            SP +  +P  + L  P  D   K  +  +   GL G PG       PG PG  G  GM  
Sbjct: 731  SPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPG 790

Query: 643  FPP--GPGGP-----------MPGPHGGPG--GPVGPRLLGP--PPPPRG--------GD 677
            FP   G  GP           +PGP G PG  G +G  +LGP   P P+G        G+
Sbjct: 791  FPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLG--VLGPIGYPGPKGMKGLMGSVGE 848

Query: 678  PFWDG----------PGDPMRGGP--MRGGPG-PG----PGPYHR-GRGGRGGNEPPPPP 719
            P   G           GDP   G    +G PG PG    PGP  + G  G  G   PP P
Sbjct: 849  PGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGP 908

Query: 720  PPFRGARGGRSGGGPPNGRGGPGG-GMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMG 778
              F G  G     GP   +G PG  G+ G  G    EG  G MG   G    EG  G  G
Sbjct: 909  EGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMG-PPGAPGLEGQPGRKG 967

Query: 779  SGHRP-------------HEGPGGSMG--------------GGGGHRPHEGPGGGISGGS 811
               RP               GP G  G              G  G R   GP  G+ G  
Sbjct: 968  FPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGP-PGVPGPK 1026

Query: 812  GHRPHEGPGGGMGAGGGHRPHEGPGGSMG--GSGGHRPHEGP-GHGGPHGHRPHDVPGHR 868
            G   H G  GGMG  G   P +GP GS G  G  G +   GP G  GP G +     G R
Sbjct: 1027 GSMGHPGMPGGMGTPGEPGP-QGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQ-----GSR 1080

Query: 869  GHDHRGPPPHEHRGHDGPGHGGGGHRGHDGGHSHGG 904
            G   +GPP  + R       G  G RGH G     G
Sbjct: 1081 G--LKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPG 1114



 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 134/440 (30%), Positives = 168/440 (38%), Gaps = 69/440 (15%)

Query: 501  KESPHEPDPE-PYEPIPP--KLIP------LDEECSMDETPYVETLEPGGSGGSPDGAGG 551
            K  P EP P+ P  PI P  ++ P      + E     E      L P G+ G   G  G
Sbjct: 1125 KGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGE-QGLIG 1183

Query: 552  SKLPPVLANLMGSMGAG--KGPQG-PGGGGINVQEILTSIMGS--PNSHPSEELLKQPDY 606
             +  P L    G MG    KG +G PG  G + ++    +MG   P   P    ++ P+ 
Sbjct: 1184 QRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEG 1243

Query: 607  SDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGP-MPGPHGGPG--GPVG 663
                +      G  G    A G+      G  G    P  PG P  PGP G  G  GP G
Sbjct: 1244 KSGKQGEKGRTGAKG----AKGYQ-----GQLGEMGVPGDPGPPGTPGPKGSRGSLGPTG 1294

Query: 664  -PRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPF 722
             P  +G    P  G   +DG    +  GP+ G PGP      +G  G+   E PP PP  
Sbjct: 1295 APGRMGAQGEP--GLAGYDGHKGIV--GPL-GPPGPKGEKGEQGEDGKA--EGPPGPPGD 1347

Query: 723  RGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMG-SGH 781
            RG  G R   G P   G PG   V G   +P            G   H GP G  G  G 
Sbjct: 1348 RGPVGDRGDRGEPGDPGYPGQEGVQGLRGKP---------GQQGQPGHPGPRGWPGPKGS 1398

Query: 782  RPHEGPGGSMG--GGGGHRPHEGPGG-----GISGGSGHRPHEGPGGGMGAGG--GHRPH 832
            +  EGP G  G  G  G R  +G  G     G+ G  G     GP G  G  G  G +  
Sbjct: 1399 KGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGE 1458

Query: 833  EGPGGSMG--GSGGHRPHEG----PGHGGPHGHRPHD-VPGHRGHDHRGPPPHEHRGHDG 885
            +G  G  G  G  G R + G    PG  GP G +    +PG  G       P   RG +G
Sbjct: 1459 QGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLG-------PPGKRGTEG 1511

Query: 886  PGHGGGGHRGHDGGHSHGGD 905
               G  G++G  G     GD
Sbjct: 1512 -RTGLPGNQGEPGSKGQPGD 1530



 Score = 81.6 bits (200), Expect = 3e-15
 Identities = 117/351 (33%), Positives = 130/351 (37%), Gaps = 66/351 (18%)

Query: 616 PHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPG--------GPMPG-PHGGPGGPVG-PR 665
           P GL G   I     P GP GP G    P  PG        G  PG  H G  G +G P 
Sbjct: 638 PPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPG 697

Query: 666 LLG-PPPPPRGGDPFWDGPGDPMRGGP-MRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFR 723
           L G P PP R G   + GP     G P  +G PGP   P  +G  GR G   P   P  +
Sbjct: 698 LSGNPGPPGRKGHKGYPGPA----GHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPK 753

Query: 724 GARG--GRSG----GGPPNGRGGPG-------GGMVGGGGHRPHEGPGGGMGNSSGHRPH 770
           G+RG  G  G     G    RG PG        GM G  G     GP G  GN  G    
Sbjct: 754 GSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGN-PGELGL 812

Query: 771 EGPGGGMG-------SGHRPHEGPGGSMG--GGGGHRPHEGPGG--GISGGSGHRPHEGP 819
            GP G  G        G   + GP G  G  G  G    +G  G  G+ G SG    +G 
Sbjct: 813 PGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGD 872

Query: 820 GGGMGAGG--GHRPHEGPGGSMGGSG-----GHRPHEG-------PGHGGPHGHR----P 861
            G  G  G  G R   GP G +G  G     G    EG       PG  GP G +     
Sbjct: 873 KGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGA 932

Query: 862 HDVPGHRG----HDHRGP--PPHEHRGHDGPGHGG-GGHRGHDGGHSHGGD 905
             +PG RG        GP  PP        PG  G  G  G DG     GD
Sbjct: 933 RGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGD 983



 Score = 80.5 bits (197), Expect = 7e-15
 Identities = 114/361 (31%), Positives = 141/361 (39%), Gaps = 45/361 (12%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
            P G+ G P G+ GS  P      MG+ G       PG  G +  + +   +G P   P  
Sbjct: 1277 PPGTPG-PKGSRGSLGPTGAPGRMGAQGE------PGLAGYDGHKGIVGPLGPPG--PKG 1327

Query: 599  ELLKQPDYSDKIKQMLVPHGLLGP-GPIANGFPPGGPGGP-----KGMQHFPPGPGGP-M 651
            E  +Q +   K +    P G  GP G   +   PG PG P     +G++  P   G P  
Sbjct: 1328 EKGEQGE-DGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGH 1386

Query: 652  PGPHGGPG--------GPVGPRLLGPPPPPRG--GDPFWDGPGDPMRGGPMRGGPGPGPG 701
            PGP G PG        GP G +     P  RG  G     GP   +    + G  GP   
Sbjct: 1387 PGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGL 1446

Query: 702  PYHRGRGGR---GGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPG 758
            P   G+ G+    G++  P P    G RG     G P  +G P  G  G  G     GP 
Sbjct: 1447 PGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPP--GFKGESGLPGQLGPP 1504

Query: 759  GGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMG--GGGGHRPHEGPGGGISGGSGHRPH 816
            G  G + G     G  G  GS  +P  G  G MG  G  G    +GP G I G  G +  
Sbjct: 1505 GKRG-TEGRTGLPGNQGEPGSKGQP--GDSGEMGFPGMAGLFGPKGPPGDI-GFKGIQGP 1560

Query: 817  EGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHG-HRPHDVPGHRGHDHRGP 875
             GP G MG  G      GP G +G SG   P    G  G  G   P   PG RG    GP
Sbjct: 1561 RGPPGLMGKEG----IVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRP--GP 1614

Query: 876  P 876
            P
Sbjct: 1615 P 1615



 Score = 73.6 bits (179), Expect = 8e-13
 Identities = 97/323 (30%), Positives = 114/323 (35%), Gaps = 51/323 (15%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQG-PGGGGINVQEILTSIMGSPNSHPS 597
            P G  G     G ++ PP      G +G  +G +G PG  G   QE +  + G P     
Sbjct: 1325 PKGEKGEQGEDGKAEGPPGPPGDRGPVG-DRGDRGEPGDPGYPGQEGVQGLRGKPGQQG- 1382

Query: 598  EELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPG--GPKGMQHFPPGPGGP----- 650
                 QP +               PGP     P G  G  GPKG Q     PG       
Sbjct: 1383 -----QPGH---------------PGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGL 1422

Query: 651  --MPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRG 708
              +PGP G  G      + GP      G P  DG           G PGP      RG  
Sbjct: 1423 QGLPGPRGVVGRQGLEGIAGPD-----GLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNP 1477

Query: 709  GRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGG----GMVGGGGHRPHEGPGGGMG-- 762
            G  G      PP F+G  G     GPP  RG  G     G  G  G +   G  G MG  
Sbjct: 1478 GVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFP 1537

Query: 763  NSSGHRPHEGPGGGMG-SGHRPHEGPGGSMGGGG--GHRPHEGPGG-----GISGGSGHR 814
              +G    +GP G +G  G +   GP G MG  G  G     GP G     G  G  G  
Sbjct: 1538 GMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDW 1597

Query: 815  PHEGPGGGMGAGGGHRPHEGPGG 837
              +GP G  G  G   P   PGG
Sbjct: 1598 GLQGPRGPPGPRGRPGPPGPPGG 1620



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 47/143 (32%), Positives = 53/143 (37%), Gaps = 26/143 (18%)

Query: 616  PHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGP----MPGPHGGPGGPVGPRLLGPPP 671
            P G  G   +     P G  G +G    P   G P     PG  G  G P    L GP  
Sbjct: 1488 PPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKG 1547

Query: 672  PPRGGDPFWDGPGDPMRGGP-MRG-----------GPGPGPGPY-HRGRGGRGGNEPPPP 718
            PP  GD  + G   P RG P + G           GP   PGP   +G  G  G + P  
Sbjct: 1548 PP--GDIGFKGIQGP-RGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRG 1604

Query: 719  PPPFRGARGGRSGGGPPNGRGGP 741
            PP      G R   GPP   GGP
Sbjct: 1605 PP------GPRGRPGPPGPPGGP 1621



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 46/130 (35%), Positives = 55/130 (42%), Gaps = 39/130 (30%)

Query: 538  EPGGSG--GSPDGAG--GSKLPPVLANLMGSMGAGKGPQGPGGG-GINVQEILTSIMGSP 592
            +PG SG  G P  AG  G K PP      G +G  KG QGP G  G+  +E +   +G  
Sbjct: 1527 QPGDSGEMGFPGMAGLFGPKGPP------GDIGF-KGIQGPRGPPGLMGKEGIVGPLG-- 1577

Query: 593  NSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMP 652
                                +L P GL GP          G  GP+G    PPGP G  P
Sbjct: 1578 --------------------ILGPSGLPGPKGDKGSRGDWGLQGPRG----PPGPRG-RP 1612

Query: 653  GPHGGPGGPV 662
            GP G PGGP+
Sbjct: 1613 GPPGPPGGPI 1622


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score =  108 bits (271), Expect = 2e-23
 Identities = 146/451 (32%), Positives = 164/451 (36%), Gaps = 102/451 (22%)

Query: 539  PGGSGGSPDGAGGSKLP--PVLANLMGSMGAGKGPQGP----GGGGINVQEILTSIMGSP 592
            P GS G     G   LP  P      GS+G   GP GP    G  G   Q  L    G P
Sbjct: 777  PPGSAGEKGKLGVPGLPGYPGRPGPKGSIGF-PGPLGPIGEKGKSGKTGQPGLEGERGPP 835

Query: 593  NSHPSEE---LLKQPDYSDKIKQMLVPH--------GLLGPGPIANGFP-PGGPGGPKGM 640
             S           QP     + Q   P         GL GP     GFP P GP G +G 
Sbjct: 836  GSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPP----GFPGPKGPPGHQGK 891

Query: 641  -----------------QHFPPGPGGPMPGPHGGPG--GPVGPRLLGPPPPP----RGGD 677
                             Q  PPGP G + GP G  G  GP+G R  GPP PP      G 
Sbjct: 892  DGRPGHPGQRGELGFQGQTGPPGPAGVL-GPQGKTGEVGPLGER--GPPGPPGPPGEQGL 948

Query: 678  PFWDG----------PGDPMRGGP--MRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGA 725
            P  +G          PG   + GP  +RG PGP  GP   G  G  G++ PP P    G+
Sbjct: 949  PGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGS 1008

Query: 726  RGGRSGGGPPNGRGGPG----------GGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGG 775
             G R   GP  G G PG           G  G  G R   GP G  G      P   PG 
Sbjct: 1009 PGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGA 1068

Query: 776  GMGSGHRPHEGPGGSMG--GGGGHRPHEGPGG--GISGGSGHRPHEGPGGGMGAGGGHRP 831
               SG    +G  G+ G  G  G +   GP G  GI G +G   H GP G  GA G   P
Sbjct: 1069 AGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAG---HPGPPGADGAQGRRGP 1125

Query: 832  -----HEGPGGSMGGSGGHRPHEGPGHGGPHGHR----------PHDVPGHRGHDHRGPP 876
                  +G  G  G  G   P    G  GP G +          PH  PG RG       
Sbjct: 1126 PGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRG------- 1178

Query: 877  PHEHRGHDG-PG-HGGGGHRGHDGGHSHGGD 905
            P    G +G PG  GG G  G  G     GD
Sbjct: 1179 PQGPTGSEGTPGLPGGVGQPGAVGEKGERGD 1209



 Score =  103 bits (256), Expect = 1e-21
 Identities = 117/360 (32%), Positives = 131/360 (36%), Gaps = 71/360 (19%)

Query: 603 QPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGPHGGPGGPV 662
           +P   +K +Q   P G  GP  +     P GP GP G     PG  GP PGP G PG P 
Sbjct: 380 EPAVIEKGQQFEGPPGAPGPQGVVG---PSGPPGPPGF----PGDPGP-PGPAGLPGIPG 431

Query: 663 GPRLLGPP------PPPRGGDPFWDGPGD---------------PMRGGP----MRGGPG 697
              + GPP      P    G  F   P                  M+G P    + G PG
Sbjct: 432 IDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPG 491

Query: 698 PGPGPYHRGRGGRGGNEPPPPP--------PPFR----------GARGGRSGGGPPNGRG 739
           P   P H G  G  G E P  P        PP R          GARG     GP   RG
Sbjct: 492 PVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRG 551

Query: 740 GPG-GGMVGGGGHRPHEGPGG--GMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGG 796
             G  G+ G  G R   G  G  G     G R  EGP G  G    P  GP G +G  G 
Sbjct: 552 FDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEP--GPRGLLGPRGS 609

Query: 797 HRPHEGPG-GGISGGSGHRPHEGPGGGMGAGGGHRPH-----EGPGGSMGGSGGHRPHEG 850
             P   PG  GI G  G + + GP G  G  G    H      GP G +G  G   P   
Sbjct: 610 PGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGN 669

Query: 851 PGHGG-PHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDGGHSHGGDMSNR 909
           PG  G P    P   PGH G       P   +G  GP  G  G  G+ G     G   NR
Sbjct: 670 PGIPGLPGSDGPLGHPGHEG-------PTGEKGAQGP-PGSAGPPGYPGPRGVKGTSGNR 721



 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 136/396 (34%), Positives = 155/396 (39%), Gaps = 80/396 (20%)

Query: 539  PGGSGGSP--DGAGGSKLPPVLANLMGSMGAGK-----GPQG----PGGGGINVQEILTS 587
            P G  G P  DGA G + PP L    G  G        GP G    PG  G   +     
Sbjct: 1107 PAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVG 1166

Query: 588  IMGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIA---------NGFPPGGPG--G 636
             MG P+  P     + P  S+    +  P G+  PG +          +  PPG PG  G
Sbjct: 1167 SMG-PHGAPGPRGPQGPTGSEGTPGL--PGGVGQPGAVGEKGERGDAGDPGPPGAPGIPG 1223

Query: 637  PKGM-----QHFPPGPGGPMPGPHGGPG--------GPVG-PRLLGPPPPPR----GGDP 678
            PKG         P G  GP PG  G PG        GP G P  LGPP  P      G P
Sbjct: 1224 PKGDIGEKGDSGPSGAAGP-PGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSP 1282

Query: 679  FWDG-PGDPMRGGP--MRGGPG-PGP----GPY-HRGRGGRGGN-----EPPPPPPPFR- 723
               G PGD    GP    G PG PGP    GP  H GR GR G      EP P  PP R 
Sbjct: 1283 GEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRT 1342

Query: 724  ---GARGGRSGGGPPNGRGGPGG----GMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGG 776
               GARG     GP   RG PG     G++G  G     GP G  G   G +   GP G 
Sbjct: 1343 GPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSG-LPGLKGDTGPKGE 1401

Query: 777  MGSGHRPHEGPGGSMG--GGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEG 834
             G     H G  G +G  G  G +  +G  G + G  G +   GP G +G+ G    H G
Sbjct: 1402 KG-----HIGLIGLIGPPGEAGEKGDQGLPG-VQGPPGPKGDPGPPGPIGSLG----HPG 1451

Query: 835  PGGSMGGSGGHRPHEGPGHGGPHGHR-PHDVPGHRG 869
            P G  G  G       PG  GP G   P   PG  G
Sbjct: 1452 PPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPG 1487



 Score = 99.0 bits (245), Expect = 2e-20
 Identities = 134/432 (31%), Positives = 161/432 (37%), Gaps = 81/432 (18%)

Query: 539 PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGG-GGINVQEILTSIMGSPNSH-- 595
           P G  G P   G    P     L G  GA +GPQGP G  G +        MG P +   
Sbjct: 483 PVGLTGRPGPVGLPGHP----GLKGEEGA-EGPQGPRGLQGPHGPPGRVGKMGRPGADGA 537

Query: 596 ---PSEELLKQPDYSDKIKQMLVPHGLLGP-GPIANGFPPG--------GPGGPKGMQHF 643
              P +   K     D +  +    G  G  G +    PPG        GP GP G Q  
Sbjct: 538 RGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTG-QAG 596

Query: 644 PPGPGGPM-----PGPHGGPG------GPVGPRLLGPPPPPRGGDPFWDGP-GDPMRGGP 691
            PGP G +     PGP G PG       P     +GPP  P  G P   G  G     GP
Sbjct: 597 EPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEP--GPPGQQGNHGSQGLPGP 654

Query: 692 --MRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG----GGM 745
             + G PG    P + G  G  G++ P   P   G  G +   GPP   G PG     G+
Sbjct: 655 QGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGV 714

Query: 746 VGGGGHRPHEGPGGGMGNSS--GHRPHEGPGGGMGS----GHRPHEGPGGSMGGGGGHRP 799
            G  G+R  +G  G  G     G +   G  G  G     G R  +GP G   G  G   
Sbjct: 715 KGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPK-GQAGQAG 773

Query: 800 HEGPGG--------GISGGSGHRPHEGPGGGMGAGG-----GHRPHEGPGGSMG------ 840
            EGP G        G+ G  G+    GP G +G  G     G +   G  G  G      
Sbjct: 774 EEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERG 833

Query: 841 --GSGGHRPHEG-PGHGGPHGHRPHD----VPGHRG-HDHRGPPPHEHRGHDGPGHGGGG 892
             GS G R   G  G  GP G    D    +PG +G    +GPP     G  GP  G  G
Sbjct: 834 PPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPP-----GFPGP-KGPPG 887

Query: 893 HRGHDGGHSHGG 904
           H+G DG   H G
Sbjct: 888 HQGKDGRPGHPG 899



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 76/248 (30%), Positives = 93/248 (37%), Gaps = 51/248 (20%)

Query: 539  PGGSGGSPDGAGGSKLP--------PVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMG 590
            P G  G+    G + LP        P ++ + GS G    P   GG G           G
Sbjct: 1248 PPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPG 1307

Query: 591  SPNSH-PSEELLKQPDYSDK-IKQMLVPHGLLG-PGPIANGFPPG-----------GPGG 636
             P    PS  + ++    +K  K    P G  G  GP+    PPG           GP G
Sbjct: 1308 PPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVG 1367

Query: 637  PKGMQHFPP--GPGGPMPGPHGGPG--GPVGPR----------LLGPPPPP--RG--GDP 678
              G+   P   GP GP+ GP G PG  G  GP+          L+GPP     +G  G P
Sbjct: 1368 EPGLLGAPGQMGPPGPL-GPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLP 1426

Query: 679  FWDGPGDPMRGGPMRGGPGP-----GPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGG 733
               GP  P +G P  G PGP      PGP   G  G  G +     P   G RG     G
Sbjct: 1427 GVQGPPGP-KGDP--GPPGPIGSLGHPGP--PGVAGPLGQKGSKGSPGSMGPRGDTGPAG 1481

Query: 734  PPNGRGGP 741
            PP   G P
Sbjct: 1482 PPGPPGAP 1489



 Score = 38.5 bits (88), Expect = 0.030
 Identities = 45/145 (31%), Positives = 50/145 (34%), Gaps = 45/145 (31%)

Query: 538  EPG-----GSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQG----------PGGGGINVQ 582
            EPG     G  G P   G S LP     L G  G  KG +G          PG  G    
Sbjct: 1368 EPGLLGAPGQMGPPGPLGPSGLP----GLKGDTGP-KGEKGHIGLIGLIGPPGEAGEKGD 1422

Query: 583  EILTSIMGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLGP-GPIANGFPPGGPG--GPKG 639
            + L  + G P                       P G  GP GPI +   PG PG  GP G
Sbjct: 1423 QGLPGVQGPPG----------------------PKGDPGPPGPIGSLGHPGPPGVAGPLG 1460

Query: 640  MQHFPPGPGGPMPGPHGGPGGPVGP 664
             +     PG   P    GP GP GP
Sbjct: 1461 QKGSKGSPGSMGPRGDTGPAGPPGP 1485


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  108 bits (269), Expect = 3e-23
 Identities = 128/400 (32%), Positives = 149/400 (37%), Gaps = 61/400 (15%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQG----PGGGGINVQEILTSIMGSPNS 594
            P G  G P G  G K    +  L G  G  +GP+G    PG  G N ++    + G P  
Sbjct: 833  PTGDPG-PSGQAGEKGKLGVPGLPGYPGR-QGPKGSTGFPGFPGANGEKGARGVAGKPGP 890

Query: 595  HPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPM--P 652
                   + P      +    P G  GP   + G  P GP G +G    P GP GP+  P
Sbjct: 891  RGQ----RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERG----PQGPQGPVGFP 942

Query: 653  GPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRG-GPGPGPGPYHRGRGGRG 711
            GP G PG P    L G P   RG   F    G P  GG +   GP    GP     G RG
Sbjct: 943  GPKGPPGPPGKDGLPGHPGQ-RGETGFQGKTGPPGPGGVVGPQGPTGETGPI----GERG 997

Query: 712  GNEPPPPP-----PPFRGARGGRSGGGPP--NGRGGPGGGMVGGGGHRPHEGPGGGMGNS 764
               PP PP     P   G  G +   GP   +G+ GP G + G  G R   G  G  G  
Sbjct: 998  HPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG-LRGFPGERGLPGAQGAPGLK 1056

Query: 765  SGHRPHEGPGGGMG----SGHRPHEGPGGSMGGGGGHRPHEGPG-GGISGGSGHRPHEGP 819
             G    EGP G  G     G R   G  G +G  G   P   PG  G  G  G +  +GP
Sbjct: 1057 GG----EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGP 1112

Query: 820  GGGMGAGG--GHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPP 877
             G  G  G  G     GP GS G  G       PG  G  G +  + P        GPP 
Sbjct: 1113 AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP-------PGPP- 1164

Query: 878  HEHRGHDGP--------GHGGGGHRGHDGGHSHGGDMSNR 909
                G  GP        G G  G RG  G     GD   R
Sbjct: 1165 ----GLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1200



 Score =  107 bits (268), Expect = 4e-23
 Identities = 138/430 (32%), Positives = 163/430 (37%), Gaps = 108/430 (25%)

Query: 539 PGGSGG----SPDGAGGSKLPPVLANLMGSMG--AGKGPQGP----GGGGINVQEILTSI 588
           PG  GG       GA G +    L  L G  G    +GPQGP    G  G+  ++     
Sbjct: 594 PGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP 653

Query: 589 MGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHF--PPG 646
            G P                       P GLLGP        PG PG P GM     PPG
Sbjct: 654 RGLPGEAG-------------------PRGLLGPRGT-----PGAPGQP-GMAGVDGPPG 688

Query: 647 PGGPMPGPHGGPGGPVGPRLLGPP--PPPRG--GDPFWDGPGDPMRGGP-MRGGPGPGPG 701
           P G M GP G PG P      GP   P P+G  G P   GP    +G P + G PG    
Sbjct: 689 PKGNM-GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP----QGKPGLAGLPGADGP 743

Query: 702 PYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGG----GMVGGGGHRPHEG- 756
           P H G+ G+ G +    PP      G +   G P  RG  G     G+ G  G +  +G 
Sbjct: 744 PGHPGKEGQSGEKGALGPP------GPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGF 797

Query: 757 PG--GGMG--------NSSGHRPHEGPGGGMG-SGHRPHEGPGGSMGGGG--------GH 797
           PG  G MG           G R  +GP G  G +G     GP G  G  G        G+
Sbjct: 798 PGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGY 857

Query: 798 RPHEGPGG-----------------GISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMG 840
              +GP G                 G++G  G R   GP G  G+ G   P  G  G  G
Sbjct: 858 PGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP-TGKPGPKG 916

Query: 841 GSGGHRPHEGPGHGGPHGHR-PHDVPGHRGHDHRGPPPHEHRGHDG-PGH----GGGGHR 894
            SGG  P   PG  GP G + P   PG +G    GPP     G DG PGH    G  G +
Sbjct: 917 TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPP--GPP-----GKDGLPGHPGQRGETGFQ 969

Query: 895 GHDGGHSHGG 904
           G  G    GG
Sbjct: 970 GKTGPPGPGG 979



 Score =  107 bits (268), Expect = 4e-23
 Identities = 136/409 (33%), Positives = 151/409 (36%), Gaps = 65/409 (15%)

Query: 536  TLEPGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGG-GGINVQEILTSIMGSPNS 594
            T  P G  G P   G    PP  A   G+ G  KGPQGP G  G+     L    G P  
Sbjct: 1079 TAGPIGLPGRPGPQG----PPGPAGEKGAPGE-KGPQGPAGRDGVQGPVGLPGPAG-PAG 1132

Query: 595  HPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPG--GPKGMQHFPPGPGGPMP 652
             P E+        DK  ++  P      G      PPG PG  GP G      G G P P
Sbjct: 1133 SPGED-------GDK-GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGP 1184

Query: 653  -GPHG--GPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPM--RGGPGPGPGPYHRGR 707
             G  G  G  G  G R    PP P G       PG+    G +   G PGP PGP  RG 
Sbjct: 1185 RGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP-PGP--RGP 1241

Query: 708  GGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG-------GGMVGGGGHRPHEGPGGG 760
             G  G + P  PP   G+ GG    G P   G PG       GG  G  G +   GP G 
Sbjct: 1242 QGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGA 1301

Query: 761  MG--------NSSGHRPHEGPGGGMGSGHRPHE-GPGGSMGGGG-----GHRPHEGPGG- 805
             G           G + + GP G  G    P E GP G  G GG     G     GP G 
Sbjct: 1302 AGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGP 1361

Query: 806  -GISGGSGHRPHEGPGGGMGAGG--------GHRPHEGPGGSMGGSGGHRPHEGPG---- 852
             G +G  G     GP G  GA G        G    EGP G  G  G   P   PG    
Sbjct: 1362 SGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGL 1421

Query: 853  HGGPHGHRPHDVPGHRGHDHRGPP-PHEHRGHDG--PGHGGGGHRGHDG 898
             G P       +PG  G D  GPP P    G  G     G  G +GH G
Sbjct: 1422 RGIPGPVGEQGLPGAAGQD--GPPGPMGPPGLPGLKGDPGSKGEKGHPG 1468



 Score =  102 bits (255), Expect = 1e-21
 Identities = 118/360 (32%), Positives = 134/360 (37%), Gaps = 85/360 (23%)

Query: 616 PHGLLGP----GPIANGFPPGGPG--GPKGMQHFP-----PGPGGPM---PGPHGGPG-- 659
           P G++GP    GP     PPG PG  GP G    P     PGP G M   P  +GG G  
Sbjct: 461 PAGIMGPPGLQGPTG---PPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 517

Query: 660 -----------------------GPVGPRLLGPPPPPRGGDPFWDGP----GDPMRGGP- 691
                                  GP GP  L   P P GG P   G     GDP   GP 
Sbjct: 518 GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGG-PGSSGAKGESGDPGPQGPR 576

Query: 692 -MRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGG 750
            ++G PGP   P  RGR G  G    P  P   GA+G R   G P        G+ G  G
Sbjct: 577 GVQGPPGPTGKPGKRGRPGADGGRGMPGEP---GAKGDRGFDGLP--------GLPGDKG 625

Query: 751 HRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHE-GPGGSMGGGGGHRPHEGPG-GGIS 808
           HR   GP G  G   G     G  G +G    P E GP G +G  G       PG  G+ 
Sbjct: 626 HRGERGPQGPPG-PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVD 684

Query: 809 GGSGHRPHEGPGGGMGAGG-----GHRPHEGPGGSMGGSGGHRPHEGPGHGG-PHGHRPH 862
           G  G + + GP G  G  G     G +   GP G +G  G   P   PG  G P    P 
Sbjct: 685 GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 744

Query: 863 DVPGHRGHDHR----GPP-PHEHRGHDGPG-----------HGGGGHRGHDGGHSHGGDM 906
             PG  G        GPP P    G+ GP             G  G +G DG     GDM
Sbjct: 745 GHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDM 804



 Score =  102 bits (255), Expect = 1e-21
 Identities = 139/432 (32%), Positives = 162/432 (37%), Gaps = 100/432 (23%)

Query: 539  PGGSGG-SPDGAGGSKLPPVLANLMGSMGA----GK-------------GPQGP----GG 576
            PG  G   P G  G +  P LA L G+ G     GK             GPQGP    G 
Sbjct: 714  PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGP 773

Query: 577  GGINVQEILTSIMGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGG 636
             G+   + +  + GS      +     P +   +       GL G         P G  G
Sbjct: 774  RGVKGADGVRGLKGSKGEKGEDGF---PGFKGDM-------GLKGDRGEVGQIGPRGEDG 823

Query: 637  PKGMQHFPPGPGGPM--PGPHG--GPGGPVG-PRLLGPP--PPPRGGDPFWDGPGDPMRG 689
            P+G    P G  GP   PGP G  G  G +G P L G P    P+G   F   PG P   
Sbjct: 824  PEG----PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF---PGFPGAN 876

Query: 690  GP-----MRGGPGP----GP-GPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRG 739
            G      + G PGP    GP GP    RG RG   P   P P +G  GG    GPP  RG
Sbjct: 877  GEKGARGVAGKPGPRGQRGPTGP----RGSRGARGPTGKPGP-KGTSGGDGPPGPPGERG 931

Query: 740  GPG-GGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGG--- 795
              G  G VG  G +   GP G  G   GH    G  G  G    P  GPGG +G  G   
Sbjct: 932  PQGPQGPVGFPGPKGPPGPPGKDG-LPGHPGQRGETGFQGKTGPP--GPGGVVGPQGPTG 988

Query: 796  -----GHRPHEGPGG-----GISGGSGHRPHEGPGGGMGAGG-----------GHRPHEG 834
                 G R H GP G     G+ G +G    +G  G  G  G           G R   G
Sbjct: 989  ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 1048

Query: 835  PGGSMGGSGGHRPHEGPGHGGPHGHR-------PHDVPGHRGHDHRGPP-PHEHRGHDGP 886
              G+ G  GG  P   PG  G  G R       P  +PG  G   +GPP P   +G  G 
Sbjct: 1049 AQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG--PQGPPGPAGEKGAPGE 1106

Query: 887  GHGGGGHRGHDG 898
              G  G  G DG
Sbjct: 1107 -KGPQGPAGRDG 1117



 Score =  102 bits (255), Expect = 1e-21
 Identities = 136/420 (32%), Positives = 154/420 (36%), Gaps = 85/420 (20%)

Query: 538  EPGGSGGSPD-GAGGSKLPPVLANLMGSMG--AGKGPQGPGGG----GINVQEILTSIMG 590
            EPG  G   D G  G   PP L   +G+ G   G G  GP G     G    E      G
Sbjct: 1145 EPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1204

Query: 591  SPNSHPSEELLKQPDYSDKIKQM--LVPHGLLGP----GPIANGFPPGGPG-----GPKG 639
             P     + L   P    +   +  + P G  GP    GP     P G PG     G  G
Sbjct: 1205 PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVG 1264

Query: 640  MQHFPPGPGGPMPGPHGGPGGPVGPR----LLGPP----PPPRGGDPFWDGP-GDPMRGG 690
             +  P   G P P    G GGP G R      GPP    PP   G P  DGP G+P   G
Sbjct: 1265 EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP---G 1321

Query: 691  PMR--GGPGPGPGPYHRGRGGRGGN-----EPPPPPPPFRGARGGRSGGGPPNGRGGPGG 743
            P+   G PGP   P   G+ G GG+     +P  P PP  G  G     GPP  RG PG 
Sbjct: 1322 PVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPP--GPSGEAGPPGPPGKRGPPGA 1379

Query: 744  -------GMVGGGGHRPHEGPGGGMG-----------NSSGHRPHEGPGGGMG-SGHRPH 784
                   G  G  G    EGP G  G              G R   GP G  G  G    
Sbjct: 1380 AGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ 1439

Query: 785  EGPGGSMG-----------GGGGHRPHEGPGG-----GISGGSGHRPHEGPGGGMGA-GG 827
            +GP G MG           G  G + H G  G     G  G  G R   G  G  GA G 
Sbjct: 1440 DGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGD 1499

Query: 828  GHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVP-GHRGHDHRGPPPHEHRGHDGP 886
            G  P  GP G +G  G   P   PG  GP G++    P G +G      PP    G  GP
Sbjct: 1500 GGIP--GPAGPLGPPG---PPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPP----GSPGP 1550



 Score =  101 bits (251), Expect = 4e-21
 Identities = 123/357 (34%), Positives = 141/357 (39%), Gaps = 45/357 (12%)

Query: 539  PGGSGGSPD-GAGGSKLPPVLANLMGSMGAGKGPQGPGG-----GGINVQEILTSIMGSP 592
            PG  G + D G  G   PP      G  GA  GPQGP G     GG+  ++      G+P
Sbjct: 1218 PGEKGENGDVGPMGPPGPPGPRGPQGPNGAD-GPQGPPGSVGSVGGVG-EKGEPGEAGNP 1275

Query: 593  NSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPG--GPGGPKGMQHFPPGPGGP 650
               P E  +  P      K    P G  GP P A G PPG  GP G  G   FP  PG P
Sbjct: 1276 GP-PGEAGVGGPKGERGEKGEAGPPGAAGP-PGAKG-PPGDDGPKGNPGPVGFPGDPGPP 1332

Query: 651  -MPGPHG--GPGGPVG----PRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPY 703
              PGP G  G GG  G    P   GPP P     P    PG P + GP  G  G      
Sbjct: 1333 GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGP----PGPPGKRGPP-GAAGAEGRQG 1387

Query: 704  HRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGG-GMVGGGGHRPHEGPGGGMG 762
             +G  G  G E PP      G +G     GP   RG PG  G  G  G    +GP G MG
Sbjct: 1388 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1447

Query: 763  -----------NSSGHRPHEGPGGGMGS-GHRPHEGPGGSMGGGGGHRPHEGPGGGISGG 810
                        S G + H G  G +G  G +  +G  G  G  G   P     GGI G 
Sbjct: 1448 PPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGS--PGAKGDGGIPGP 1505

Query: 811  SGHRPHEGPGGGMGAGG--GHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVP 865
            +G     GP G  G  G  G++   GP G  G SG   P   PG  GP G     +P
Sbjct: 1506 AGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP---PGSPGPPGEVIQPLP 1559



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 78/273 (28%), Positives = 94/273 (34%), Gaps = 80/273 (29%)

Query: 504  PHEPDPEPYEPIPPKLIPLDEECSMDETPYVETLEPGGSG-GSPDGAGGSKLPPVLANLM 562
            P +P P P EP P     +  +   D  P  +   PG SG   P G  G + PP  A   
Sbjct: 1326 PGDPGP-PGEPGPAGQDGVGGDKGEDGDPG-QPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1383

Query: 563  GSMG-----AGKGPQGPGG--GGINVQEILTSIMGSPNSHPSEELLKQPDYSDKIKQMLV 615
            G  G        G +GP G  G +  Q         P   P  E L+       + +  +
Sbjct: 1384 GRQGEKGAKGEAGAEGPPGKTGPVGPQ--------GPAGKPGPEGLR--GIPGPVGEQGL 1433

Query: 616  PHGLLGPGPIANGFPPGGPG-----GPKGMQHFP--------PGPGGP-----MPGPHGG 657
            P      GP     PPG PG     G KG +  P        PG  G      +PG  G 
Sbjct: 1434 PGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGS 1493

Query: 658  PG--------GPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGG 709
            PG        GP GP  LGPP PP                    G PGP  GP    +G 
Sbjct: 1494 PGAKGDGGIPGPAGP--LGPPGPP--------------------GLPGP-QGP----KGN 1526

Query: 710  RGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG 742
            +G   P        G +G     GPP   G PG
Sbjct: 1527 KGSTGP-------AGQKGDSGLPGPPGSPGPPG 1552


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  108 bits (269), Expect = 3e-23
 Identities = 128/400 (32%), Positives = 149/400 (37%), Gaps = 61/400 (15%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQG----PGGGGINVQEILTSIMGSPNS 594
            P G  G P G  G K    +  L G  G  +GP+G    PG  G N ++    + G P  
Sbjct: 782  PTGDPG-PSGQAGEKGKLGVPGLPGYPGR-QGPKGSTGFPGFPGANGEKGARGVAGKPGP 839

Query: 595  HPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPM--P 652
                   + P      +    P G  GP   + G  P GP G +G    P GP GP+  P
Sbjct: 840  RGQ----RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERG----PQGPQGPVGFP 891

Query: 653  GPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRG-GPGPGPGPYHRGRGGRG 711
            GP G PG P    L G P   RG   F    G P  GG +   GP    GP     G RG
Sbjct: 892  GPKGPPGPPGKDGLPGHPGQ-RGETGFQGKTGPPGPGGVVGPQGPTGETGPI----GERG 946

Query: 712  GNEPPPPP-----PPFRGARGGRSGGGPP--NGRGGPGGGMVGGGGHRPHEGPGGGMGNS 764
               PP PP     P   G  G +   GP   +G+ GP G + G  G R   G  G  G  
Sbjct: 947  HPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG-LRGFPGERGLPGAQGAPGLK 1005

Query: 765  SGHRPHEGPGGGMG----SGHRPHEGPGGSMGGGGGHRPHEGPG-GGISGGSGHRPHEGP 819
             G    EGP G  G     G R   G  G +G  G   P   PG  G  G  G +  +GP
Sbjct: 1006 GG----EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGP 1061

Query: 820  GGGMGAGG--GHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPP 877
             G  G  G  G     GP GS G  G       PG  G  G +  + P        GPP 
Sbjct: 1062 AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP-------PGPP- 1113

Query: 878  HEHRGHDGP--------GHGGGGHRGHDGGHSHGGDMSNR 909
                G  GP        G G  G RG  G     GD   R
Sbjct: 1114 ----GLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1149



 Score =  107 bits (268), Expect = 4e-23
 Identities = 138/430 (32%), Positives = 163/430 (37%), Gaps = 108/430 (25%)

Query: 539 PGGSGG----SPDGAGGSKLPPVLANLMGSMG--AGKGPQGP----GGGGINVQEILTSI 588
           PG  GG       GA G +    L  L G  G    +GPQGP    G  G+  ++     
Sbjct: 543 PGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP 602

Query: 589 MGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHF--PPG 646
            G P                       P GLLGP        PG PG P GM     PPG
Sbjct: 603 RGLPGEAG-------------------PRGLLGPRGT-----PGAPGQP-GMAGVDGPPG 637

Query: 647 PGGPMPGPHGGPGGPVGPRLLGPP--PPPRG--GDPFWDGPGDPMRGGP-MRGGPGPGPG 701
           P G M GP G PG P      GP   P P+G  G P   GP    +G P + G PG    
Sbjct: 638 PKGNM-GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP----QGKPGLAGLPGADGP 692

Query: 702 PYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGG----GMVGGGGHRPHEG- 756
           P H G+ G+ G +    PP      G +   G P  RG  G     G+ G  G +  +G 
Sbjct: 693 PGHPGKEGQSGEKGALGPP------GPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGF 746

Query: 757 PG--GGMG--------NSSGHRPHEGPGGGMG-SGHRPHEGPGGSMGGGG--------GH 797
           PG  G MG           G R  +GP G  G +G     GP G  G  G        G+
Sbjct: 747 PGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGY 806

Query: 798 RPHEGPGG-----------------GISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMG 840
              +GP G                 G++G  G R   GP G  G+ G   P  G  G  G
Sbjct: 807 PGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP-TGKPGPKG 865

Query: 841 GSGGHRPHEGPGHGGPHGHR-PHDVPGHRGHDHRGPPPHEHRGHDG-PGH----GGGGHR 894
            SGG  P   PG  GP G + P   PG +G    GPP     G DG PGH    G  G +
Sbjct: 866 TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPP--GPP-----GKDGLPGHPGQRGETGFQ 918

Query: 895 GHDGGHSHGG 904
           G  G    GG
Sbjct: 919 GKTGPPGPGG 928



 Score =  107 bits (268), Expect = 4e-23
 Identities = 136/409 (33%), Positives = 151/409 (36%), Gaps = 65/409 (15%)

Query: 536  TLEPGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGG-GGINVQEILTSIMGSPNS 594
            T  P G  G P   G    PP  A   G+ G  KGPQGP G  G+     L    G P  
Sbjct: 1028 TAGPIGLPGRPGPQG----PPGPAGEKGAPGE-KGPQGPAGRDGVQGPVGLPGPAG-PAG 1081

Query: 595  HPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPG--GPKGMQHFPPGPGGPMP 652
             P E+        DK  ++  P      G      PPG PG  GP G      G G P P
Sbjct: 1082 SPGED-------GDK-GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGP 1133

Query: 653  -GPHG--GPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPM--RGGPGPGPGPYHRGR 707
             G  G  G  G  G R    PP P G       PG+    G +   G PGP PGP  RG 
Sbjct: 1134 RGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP-PGP--RGP 1190

Query: 708  GGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG-------GGMVGGGGHRPHEGPGGG 760
             G  G + P  PP   G+ GG    G P   G PG       GG  G  G +   GP G 
Sbjct: 1191 QGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGA 1250

Query: 761  MG--------NSSGHRPHEGPGGGMGSGHRPHE-GPGGSMGGGG-----GHRPHEGPGG- 805
             G           G + + GP G  G    P E GP G  G GG     G     GP G 
Sbjct: 1251 AGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGP 1310

Query: 806  -GISGGSGHRPHEGPGGGMGAGG--------GHRPHEGPGGSMGGSGGHRPHEGPG---- 852
             G +G  G     GP G  GA G        G    EGP G  G  G   P   PG    
Sbjct: 1311 SGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGL 1370

Query: 853  HGGPHGHRPHDVPGHRGHDHRGPP-PHEHRGHDG--PGHGGGGHRGHDG 898
             G P       +PG  G D  GPP P    G  G     G  G +GH G
Sbjct: 1371 RGIPGPVGEQGLPGAAGQD--GPPGPMGPPGLPGLKGDPGSKGEKGHPG 1417



 Score =  102 bits (255), Expect = 1e-21
 Identities = 118/360 (32%), Positives = 134/360 (37%), Gaps = 85/360 (23%)

Query: 616 PHGLLGP----GPIANGFPPGGPG--GPKGMQHFP-----PGPGGPM---PGPHGGPG-- 659
           P G++GP    GP     PPG PG  GP G    P     PGP G M   P  +GG G  
Sbjct: 410 PAGIMGPPGLQGPTG---PPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 466

Query: 660 -----------------------GPVGPRLLGPPPPPRGGDPFWDGP----GDPMRGGP- 691
                                  GP GP  L   P P GG P   G     GDP   GP 
Sbjct: 467 GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGG-PGSSGAKGESGDPGPQGPR 525

Query: 692 -MRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGG 750
            ++G PGP   P  RGR G  G    P  P   GA+G R   G P        G+ G  G
Sbjct: 526 GVQGPPGPTGKPGKRGRPGADGGRGMPGEP---GAKGDRGFDGLP--------GLPGDKG 574

Query: 751 HRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHE-GPGGSMGGGGGHRPHEGPG-GGIS 808
           HR   GP G  G   G     G  G +G    P E GP G +G  G       PG  G+ 
Sbjct: 575 HRGERGPQGPPG-PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVD 633

Query: 809 GGSGHRPHEGPGGGMGAGG-----GHRPHEGPGGSMGGSGGHRPHEGPGHGG-PHGHRPH 862
           G  G + + GP G  G  G     G +   GP G +G  G   P   PG  G P    P 
Sbjct: 634 GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 693

Query: 863 DVPGHRGHDHR----GPP-PHEHRGHDGPG-----------HGGGGHRGHDGGHSHGGDM 906
             PG  G        GPP P    G+ GP             G  G +G DG     GDM
Sbjct: 694 GHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDM 753



 Score =  102 bits (255), Expect = 1e-21
 Identities = 139/432 (32%), Positives = 162/432 (37%), Gaps = 100/432 (23%)

Query: 539  PGGSGG-SPDGAGGSKLPPVLANLMGSMGA----GK-------------GPQGP----GG 576
            PG  G   P G  G +  P LA L G+ G     GK             GPQGP    G 
Sbjct: 663  PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGP 722

Query: 577  GGINVQEILTSIMGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGG 636
             G+   + +  + GS      +     P +   +       GL G         P G  G
Sbjct: 723  RGVKGADGVRGLKGSKGEKGEDGF---PGFKGDM-------GLKGDRGEVGQIGPRGEDG 772

Query: 637  PKGMQHFPPGPGGPM--PGPHG--GPGGPVG-PRLLGPP--PPPRGGDPFWDGPGDPMRG 689
            P+G    P G  GP   PGP G  G  G +G P L G P    P+G   F   PG P   
Sbjct: 773  PEG----PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF---PGFPGAN 825

Query: 690  GP-----MRGGPGP----GP-GPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRG 739
            G      + G PGP    GP GP    RG RG   P   P P +G  GG    GPP  RG
Sbjct: 826  GEKGARGVAGKPGPRGQRGPTGP----RGSRGARGPTGKPGP-KGTSGGDGPPGPPGERG 880

Query: 740  GPG-GGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGG--- 795
              G  G VG  G +   GP G  G   GH    G  G  G    P  GPGG +G  G   
Sbjct: 881  PQGPQGPVGFPGPKGPPGPPGKDG-LPGHPGQRGETGFQGKTGPP--GPGGVVGPQGPTG 937

Query: 796  -----GHRPHEGPGG-----GISGGSGHRPHEGPGGGMGAGG-----------GHRPHEG 834
                 G R H GP G     G+ G +G    +G  G  G  G           G R   G
Sbjct: 938  ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 997

Query: 835  PGGSMGGSGGHRPHEGPGHGGPHGHR-------PHDVPGHRGHDHRGPP-PHEHRGHDGP 886
              G+ G  GG  P   PG  G  G R       P  +PG  G   +GPP P   +G  G 
Sbjct: 998  AQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG--PQGPPGPAGEKGAPGE 1055

Query: 887  GHGGGGHRGHDG 898
              G  G  G DG
Sbjct: 1056 -KGPQGPAGRDG 1066



 Score =  102 bits (255), Expect = 1e-21
 Identities = 136/420 (32%), Positives = 154/420 (36%), Gaps = 85/420 (20%)

Query: 538  EPGGSGGSPD-GAGGSKLPPVLANLMGSMG--AGKGPQGPGGG----GINVQEILTSIMG 590
            EPG  G   D G  G   PP L   +G+ G   G G  GP G     G    E      G
Sbjct: 1094 EPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1153

Query: 591  SPNSHPSEELLKQPDYSDKIKQM--LVPHGLLGP----GPIANGFPPGGPG-----GPKG 639
             P     + L   P    +   +  + P G  GP    GP     P G PG     G  G
Sbjct: 1154 PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVG 1213

Query: 640  MQHFPPGPGGPMPGPHGGPGGPVGPR----LLGPP----PPPRGGDPFWDGP-GDPMRGG 690
             +  P   G P P    G GGP G R      GPP    PP   G P  DGP G+P   G
Sbjct: 1214 EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP---G 1270

Query: 691  PMR--GGPGPGPGPYHRGRGGRGGN-----EPPPPPPPFRGARGGRSGGGPPNGRGGPGG 743
            P+   G PGP   P   G+ G GG+     +P  P PP  G  G     GPP  RG PG 
Sbjct: 1271 PVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPP--GPSGEAGPPGPPGKRGPPGA 1328

Query: 744  -------GMVGGGGHRPHEGPGGGMG-----------NSSGHRPHEGPGGGMG-SGHRPH 784
                   G  G  G    EGP G  G              G R   GP G  G  G    
Sbjct: 1329 AGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ 1388

Query: 785  EGPGGSMG-----------GGGGHRPHEGPGG-----GISGGSGHRPHEGPGGGMGA-GG 827
            +GP G MG           G  G + H G  G     G  G  G R   G  G  GA G 
Sbjct: 1389 DGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGD 1448

Query: 828  GHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVP-GHRGHDHRGPPPHEHRGHDGP 886
            G  P  GP G +G  G   P   PG  GP G++    P G +G      PP    G  GP
Sbjct: 1449 GGIP--GPAGPLGPPG---PPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPP----GSPGP 1499



 Score =  101 bits (251), Expect = 4e-21
 Identities = 123/357 (34%), Positives = 141/357 (39%), Gaps = 45/357 (12%)

Query: 539  PGGSGGSPD-GAGGSKLPPVLANLMGSMGAGKGPQGPGG-----GGINVQEILTSIMGSP 592
            PG  G + D G  G   PP      G  GA  GPQGP G     GG+  ++      G+P
Sbjct: 1167 PGEKGENGDVGPMGPPGPPGPRGPQGPNGAD-GPQGPPGSVGSVGGVG-EKGEPGEAGNP 1224

Query: 593  NSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPG--GPGGPKGMQHFPPGPGGP 650
               P E  +  P      K    P G  GP P A G PPG  GP G  G   FP  PG P
Sbjct: 1225 GP-PGEAGVGGPKGERGEKGEAGPPGAAGP-PGAKG-PPGDDGPKGNPGPVGFPGDPGPP 1281

Query: 651  -MPGPHG--GPGGPVG----PRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPY 703
              PGP G  G GG  G    P   GPP P     P    PG P + GP  G  G      
Sbjct: 1282 GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGP----PGPPGKRGPP-GAAGAEGRQG 1336

Query: 704  HRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGG-GMVGGGGHRPHEGPGGGMG 762
             +G  G  G E PP      G +G     GP   RG PG  G  G  G    +GP G MG
Sbjct: 1337 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1396

Query: 763  -----------NSSGHRPHEGPGGGMGS-GHRPHEGPGGSMGGGGGHRPHEGPGGGISGG 810
                        S G + H G  G +G  G +  +G  G  G  G   P     GGI G 
Sbjct: 1397 PPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGS--PGAKGDGGIPGP 1454

Query: 811  SGHRPHEGPGGGMGAGG--GHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVP 865
            +G     GP G  G  G  G++   GP G  G SG   P   PG  GP G     +P
Sbjct: 1455 AGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP---PGSPGPPGEVIQPLP 1508



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 78/273 (28%), Positives = 94/273 (34%), Gaps = 80/273 (29%)

Query: 504  PHEPDPEPYEPIPPKLIPLDEECSMDETPYVETLEPGGSG-GSPDGAGGSKLPPVLANLM 562
            P +P P P EP P     +  +   D  P  +   PG SG   P G  G + PP  A   
Sbjct: 1275 PGDPGP-PGEPGPAGQDGVGGDKGEDGDPG-QPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1332

Query: 563  GSMG-----AGKGPQGPGG--GGINVQEILTSIMGSPNSHPSEELLKQPDYSDKIKQMLV 615
            G  G        G +GP G  G +  Q         P   P  E L+       + +  +
Sbjct: 1333 GRQGEKGAKGEAGAEGPPGKTGPVGPQ--------GPAGKPGPEGLR--GIPGPVGEQGL 1382

Query: 616  PHGLLGPGPIANGFPPGGPG-----GPKGMQHFP--------PGPGGP-----MPGPHGG 657
            P      GP     PPG PG     G KG +  P        PG  G      +PG  G 
Sbjct: 1383 PGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGS 1442

Query: 658  PG--------GPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGG 709
            PG        GP GP  LGPP PP                    G PGP  GP    +G 
Sbjct: 1443 PGAKGDGGIPGPAGP--LGPPGPP--------------------GLPGP-QGP----KGN 1475

Query: 710  RGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG 742
            +G   P        G +G     GPP   G PG
Sbjct: 1476 KGSTGP-------AGQKGDSGLPGPPGSPGPPG 1501


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  108 bits (269), Expect = 3e-23
 Identities = 128/400 (32%), Positives = 149/400 (37%), Gaps = 61/400 (15%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQG----PGGGGINVQEILTSIMGSPNS 594
            P G  G P G  G K    +  L G  G  +GP+G    PG  G N ++    + G P  
Sbjct: 821  PTGDPG-PSGQAGEKGKLGVPGLPGYPGR-QGPKGSTGFPGFPGANGEKGARGVAGKPGP 878

Query: 595  HPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPM--P 652
                   + P      +    P G  GP   + G  P GP G +G    P GP GP+  P
Sbjct: 879  RGQ----RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERG----PQGPQGPVGFP 930

Query: 653  GPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRG-GPGPGPGPYHRGRGGRG 711
            GP G PG P    L G P   RG   F    G P  GG +   GP    GP     G RG
Sbjct: 931  GPKGPPGPPGKDGLPGHPGQ-RGETGFQGKTGPPGPGGVVGPQGPTGETGPI----GERG 985

Query: 712  GNEPPPPP-----PPFRGARGGRSGGGPP--NGRGGPGGGMVGGGGHRPHEGPGGGMGNS 764
               PP PP     P   G  G +   GP   +G+ GP G + G  G R   G  G  G  
Sbjct: 986  HPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG-LRGFPGERGLPGAQGAPGLK 1044

Query: 765  SGHRPHEGPGGGMG----SGHRPHEGPGGSMGGGGGHRPHEGPG-GGISGGSGHRPHEGP 819
             G    EGP G  G     G R   G  G +G  G   P   PG  G  G  G +  +GP
Sbjct: 1045 GG----EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGP 1100

Query: 820  GGGMGAGG--GHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPP 877
             G  G  G  G     GP GS G  G       PG  G  G +  + P        GPP 
Sbjct: 1101 AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP-------PGPP- 1152

Query: 878  HEHRGHDGP--------GHGGGGHRGHDGGHSHGGDMSNR 909
                G  GP        G G  G RG  G     GD   R
Sbjct: 1153 ----GLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1188



 Score =  107 bits (268), Expect = 4e-23
 Identities = 138/430 (32%), Positives = 163/430 (37%), Gaps = 108/430 (25%)

Query: 539 PGGSGG----SPDGAGGSKLPPVLANLMGSMG--AGKGPQGP----GGGGINVQEILTSI 588
           PG  GG       GA G +    L  L G  G    +GPQGP    G  G+  ++     
Sbjct: 582 PGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP 641

Query: 589 MGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHF--PPG 646
            G P                       P GLLGP        PG PG P GM     PPG
Sbjct: 642 RGLPGEAG-------------------PRGLLGPRGT-----PGAPGQP-GMAGVDGPPG 676

Query: 647 PGGPMPGPHGGPGGPVGPRLLGPP--PPPRG--GDPFWDGPGDPMRGGP-MRGGPGPGPG 701
           P G M GP G PG P      GP   P P+G  G P   GP    +G P + G PG    
Sbjct: 677 PKGNM-GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP----QGKPGLAGLPGADGP 731

Query: 702 PYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGG----GMVGGGGHRPHEG- 756
           P H G+ G+ G +    PP      G +   G P  RG  G     G+ G  G +  +G 
Sbjct: 732 PGHPGKEGQSGEKGALGPP------GPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGF 785

Query: 757 PG--GGMG--------NSSGHRPHEGPGGGMG-SGHRPHEGPGGSMGGGG--------GH 797
           PG  G MG           G R  +GP G  G +G     GP G  G  G        G+
Sbjct: 786 PGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGY 845

Query: 798 RPHEGPGG-----------------GISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMG 840
              +GP G                 G++G  G R   GP G  G+ G   P  G  G  G
Sbjct: 846 PGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP-TGKPGPKG 904

Query: 841 GSGGHRPHEGPGHGGPHGHR-PHDVPGHRGHDHRGPPPHEHRGHDG-PGH----GGGGHR 894
            SGG  P   PG  GP G + P   PG +G    GPP     G DG PGH    G  G +
Sbjct: 905 TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPP--GPP-----GKDGLPGHPGQRGETGFQ 957

Query: 895 GHDGGHSHGG 904
           G  G    GG
Sbjct: 958 GKTGPPGPGG 967



 Score =  107 bits (268), Expect = 4e-23
 Identities = 136/409 (33%), Positives = 151/409 (36%), Gaps = 65/409 (15%)

Query: 536  TLEPGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGG-GGINVQEILTSIMGSPNS 594
            T  P G  G P   G    PP  A   G+ G  KGPQGP G  G+     L    G P  
Sbjct: 1067 TAGPIGLPGRPGPQG----PPGPAGEKGAPGE-KGPQGPAGRDGVQGPVGLPGPAG-PAG 1120

Query: 595  HPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPG--GPKGMQHFPPGPGGPMP 652
             P E+        DK  ++  P      G      PPG PG  GP G      G G P P
Sbjct: 1121 SPGED-------GDK-GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGP 1172

Query: 653  -GPHG--GPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPM--RGGPGPGPGPYHRGR 707
             G  G  G  G  G R    PP P G       PG+    G +   G PGP PGP  RG 
Sbjct: 1173 RGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP-PGP--RGP 1229

Query: 708  GGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG-------GGMVGGGGHRPHEGPGGG 760
             G  G + P  PP   G+ GG    G P   G PG       GG  G  G +   GP G 
Sbjct: 1230 QGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGA 1289

Query: 761  MG--------NSSGHRPHEGPGGGMGSGHRPHE-GPGGSMGGGG-----GHRPHEGPGG- 805
             G           G + + GP G  G    P E GP G  G GG     G     GP G 
Sbjct: 1290 AGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGP 1349

Query: 806  -GISGGSGHRPHEGPGGGMGAGG--------GHRPHEGPGGSMGGSGGHRPHEGPG---- 852
             G +G  G     GP G  GA G        G    EGP G  G  G   P   PG    
Sbjct: 1350 SGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGL 1409

Query: 853  HGGPHGHRPHDVPGHRGHDHRGPP-PHEHRGHDG--PGHGGGGHRGHDG 898
             G P       +PG  G D  GPP P    G  G     G  G +GH G
Sbjct: 1410 RGIPGPVGEQGLPGAAGQD--GPPGPMGPPGLPGLKGDPGSKGEKGHPG 1456



 Score =  102 bits (255), Expect = 1e-21
 Identities = 118/360 (32%), Positives = 134/360 (37%), Gaps = 85/360 (23%)

Query: 616 PHGLLGP----GPIANGFPPGGPG--GPKGMQHFP-----PGPGGPM---PGPHGGPG-- 659
           P G++GP    GP     PPG PG  GP G    P     PGP G M   P  +GG G  
Sbjct: 449 PAGIMGPPGLQGPTG---PPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 505

Query: 660 -----------------------GPVGPRLLGPPPPPRGGDPFWDGP----GDPMRGGP- 691
                                  GP GP  L   P P GG P   G     GDP   GP 
Sbjct: 506 GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGG-PGSSGAKGESGDPGPQGPR 564

Query: 692 -MRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGG 750
            ++G PGP   P  RGR G  G    P  P   GA+G R   G P        G+ G  G
Sbjct: 565 GVQGPPGPTGKPGKRGRPGADGGRGMPGEP---GAKGDRGFDGLP--------GLPGDKG 613

Query: 751 HRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHE-GPGGSMGGGGGHRPHEGPG-GGIS 808
           HR   GP G  G   G     G  G +G    P E GP G +G  G       PG  G+ 
Sbjct: 614 HRGERGPQGPPG-PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVD 672

Query: 809 GGSGHRPHEGPGGGMGAGG-----GHRPHEGPGGSMGGSGGHRPHEGPGHGG-PHGHRPH 862
           G  G + + GP G  G  G     G +   GP G +G  G   P   PG  G P    P 
Sbjct: 673 GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 732

Query: 863 DVPGHRGHDHR----GPP-PHEHRGHDGPG-----------HGGGGHRGHDGGHSHGGDM 906
             PG  G        GPP P    G+ GP             G  G +G DG     GDM
Sbjct: 733 GHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDM 792



 Score =  102 bits (255), Expect = 1e-21
 Identities = 139/432 (32%), Positives = 162/432 (37%), Gaps = 100/432 (23%)

Query: 539  PGGSGG-SPDGAGGSKLPPVLANLMGSMGA----GK-------------GPQGP----GG 576
            PG  G   P G  G +  P LA L G+ G     GK             GPQGP    G 
Sbjct: 702  PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGP 761

Query: 577  GGINVQEILTSIMGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGG 636
             G+   + +  + GS      +     P +   +       GL G         P G  G
Sbjct: 762  RGVKGADGVRGLKGSKGEKGEDGF---PGFKGDM-------GLKGDRGEVGQIGPRGEDG 811

Query: 637  PKGMQHFPPGPGGPM--PGPHG--GPGGPVG-PRLLGPP--PPPRGGDPFWDGPGDPMRG 689
            P+G    P G  GP   PGP G  G  G +G P L G P    P+G   F   PG P   
Sbjct: 812  PEG----PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF---PGFPGAN 864

Query: 690  GP-----MRGGPGP----GP-GPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRG 739
            G      + G PGP    GP GP    RG RG   P   P P +G  GG    GPP  RG
Sbjct: 865  GEKGARGVAGKPGPRGQRGPTGP----RGSRGARGPTGKPGP-KGTSGGDGPPGPPGERG 919

Query: 740  GPG-GGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGG--- 795
              G  G VG  G +   GP G  G   GH    G  G  G    P  GPGG +G  G   
Sbjct: 920  PQGPQGPVGFPGPKGPPGPPGKDG-LPGHPGQRGETGFQGKTGPP--GPGGVVGPQGPTG 976

Query: 796  -----GHRPHEGPGG-----GISGGSGHRPHEGPGGGMGAGG-----------GHRPHEG 834
                 G R H GP G     G+ G +G    +G  G  G  G           G R   G
Sbjct: 977  ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 1036

Query: 835  PGGSMGGSGGHRPHEGPGHGGPHGHR-------PHDVPGHRGHDHRGPP-PHEHRGHDGP 886
              G+ G  GG  P   PG  G  G R       P  +PG  G   +GPP P   +G  G 
Sbjct: 1037 AQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG--PQGPPGPAGEKGAPGE 1094

Query: 887  GHGGGGHRGHDG 898
              G  G  G DG
Sbjct: 1095 -KGPQGPAGRDG 1105



 Score =  102 bits (255), Expect = 1e-21
 Identities = 136/420 (32%), Positives = 154/420 (36%), Gaps = 85/420 (20%)

Query: 538  EPGGSGGSPD-GAGGSKLPPVLANLMGSMG--AGKGPQGPGGG----GINVQEILTSIMG 590
            EPG  G   D G  G   PP L   +G+ G   G G  GP G     G    E      G
Sbjct: 1133 EPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1192

Query: 591  SPNSHPSEELLKQPDYSDKIKQM--LVPHGLLGP----GPIANGFPPGGPG-----GPKG 639
             P     + L   P    +   +  + P G  GP    GP     P G PG     G  G
Sbjct: 1193 PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVG 1252

Query: 640  MQHFPPGPGGPMPGPHGGPGGPVGPR----LLGPP----PPPRGGDPFWDGP-GDPMRGG 690
             +  P   G P P    G GGP G R      GPP    PP   G P  DGP G+P   G
Sbjct: 1253 EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP---G 1309

Query: 691  PMR--GGPGPGPGPYHRGRGGRGGN-----EPPPPPPPFRGARGGRSGGGPPNGRGGPGG 743
            P+   G PGP   P   G+ G GG+     +P  P PP  G  G     GPP  RG PG 
Sbjct: 1310 PVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPP--GPSGEAGPPGPPGKRGPPGA 1367

Query: 744  -------GMVGGGGHRPHEGPGGGMG-----------NSSGHRPHEGPGGGMG-SGHRPH 784
                   G  G  G    EGP G  G              G R   GP G  G  G    
Sbjct: 1368 AGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ 1427

Query: 785  EGPGGSMG-----------GGGGHRPHEGPGG-----GISGGSGHRPHEGPGGGMGA-GG 827
            +GP G MG           G  G + H G  G     G  G  G R   G  G  GA G 
Sbjct: 1428 DGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGD 1487

Query: 828  GHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVP-GHRGHDHRGPPPHEHRGHDGP 886
            G  P  GP G +G  G   P   PG  GP G++    P G +G      PP    G  GP
Sbjct: 1488 GGIP--GPAGPLGPPG---PPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPP----GSPGP 1538



 Score =  101 bits (251), Expect = 4e-21
 Identities = 123/357 (34%), Positives = 141/357 (39%), Gaps = 45/357 (12%)

Query: 539  PGGSGGSPD-GAGGSKLPPVLANLMGSMGAGKGPQGPGG-----GGINVQEILTSIMGSP 592
            PG  G + D G  G   PP      G  GA  GPQGP G     GG+  ++      G+P
Sbjct: 1206 PGEKGENGDVGPMGPPGPPGPRGPQGPNGAD-GPQGPPGSVGSVGGVG-EKGEPGEAGNP 1263

Query: 593  NSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPG--GPGGPKGMQHFPPGPGGP 650
               P E  +  P      K    P G  GP P A G PPG  GP G  G   FP  PG P
Sbjct: 1264 GP-PGEAGVGGPKGERGEKGEAGPPGAAGP-PGAKG-PPGDDGPKGNPGPVGFPGDPGPP 1320

Query: 651  -MPGPHG--GPGGPVG----PRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPY 703
              PGP G  G GG  G    P   GPP P     P    PG P + GP  G  G      
Sbjct: 1321 GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGP----PGPPGKRGPP-GAAGAEGRQG 1375

Query: 704  HRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGG-GMVGGGGHRPHEGPGGGMG 762
             +G  G  G E PP      G +G     GP   RG PG  G  G  G    +GP G MG
Sbjct: 1376 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1435

Query: 763  -----------NSSGHRPHEGPGGGMGS-GHRPHEGPGGSMGGGGGHRPHEGPGGGISGG 810
                        S G + H G  G +G  G +  +G  G  G  G   P     GGI G 
Sbjct: 1436 PPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGS--PGAKGDGGIPGP 1493

Query: 811  SGHRPHEGPGGGMGAGG--GHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVP 865
            +G     GP G  G  G  G++   GP G  G SG   P   PG  GP G     +P
Sbjct: 1494 AGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP---PGSPGPPGEVIQPLP 1547



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 78/273 (28%), Positives = 94/273 (34%), Gaps = 80/273 (29%)

Query: 504  PHEPDPEPYEPIPPKLIPLDEECSMDETPYVETLEPGGSG-GSPDGAGGSKLPPVLANLM 562
            P +P P P EP P     +  +   D  P  +   PG SG   P G  G + PP  A   
Sbjct: 1314 PGDPGP-PGEPGPAGQDGVGGDKGEDGDPG-QPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1371

Query: 563  GSMG-----AGKGPQGPGG--GGINVQEILTSIMGSPNSHPSEELLKQPDYSDKIKQMLV 615
            G  G        G +GP G  G +  Q         P   P  E L+       + +  +
Sbjct: 1372 GRQGEKGAKGEAGAEGPPGKTGPVGPQ--------GPAGKPGPEGLR--GIPGPVGEQGL 1421

Query: 616  PHGLLGPGPIANGFPPGGPG-----GPKGMQHFP--------PGPGGP-----MPGPHGG 657
            P      GP     PPG PG     G KG +  P        PG  G      +PG  G 
Sbjct: 1422 PGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGS 1481

Query: 658  PG--------GPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGG 709
            PG        GP GP  LGPP PP                    G PGP  GP    +G 
Sbjct: 1482 PGAKGDGGIPGPAGP--LGPPGPP--------------------GLPGP-QGP----KGN 1514

Query: 710  RGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG 742
            +G   P        G +G     GPP   G PG
Sbjct: 1515 KGSTGP-------AGQKGDSGLPGPPGSPGPPG 1540


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score =  106 bits (264), Expect = 1e-22
 Identities = 132/371 (35%), Positives = 152/371 (40%), Gaps = 55/371 (14%)

Query: 538 EPGGSG--GSP--DGAGGSKLPPVLANLMGSMGAGKGPQGP-----------GGGGINVQ 582
           +PG  G  G P  DG  G   P     L+G  GA KG  G            G  G   Q
Sbjct: 493 QPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGA-KGEPGEFYFDLRLKGDKGDPGFPGQ 551

Query: 583 EILTSIMGSP--NSHPSEELLKQPDYSDKIKQMLVPHGLLG-PGPIANGFPPG----GPG 635
             +T   GSP  + HP     K    S  +K    P G +G PG   +  PPG    GP 
Sbjct: 552 PGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPA 611

Query: 636 GP---KGMQHFPPGPGGP-MPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGP 691
           GP   KG   FP GPG P +PGP G PG  V      P P P G +     PG P   G 
Sbjct: 612 GPIGDKGQAGFPGGPGSPGLPGPKGEPGKIV------PLPGPPGAEGLPGSPGFPGPQGD 665

Query: 692 MRGGPG-PG-PG-PYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG-GGMVG 747
            RG PG PG PG P  +G  G+ G   P PP P +G  G     GPP   G PG  G+ G
Sbjct: 666 -RGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGP-KGVDGLPGDMGPPGTPGRPGFNGLPG 723

Query: 748 GGGHRPHEG-PGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGG 806
             G +  +G PG G+    G     G  G          G  GS+G  G   P E    G
Sbjct: 724 NPGVQGQKGEPGVGLPGLKGLPGLPGIPG--------TPGEKGSIGVPG--VPGEHGAIG 773

Query: 807 ISGGSGHRPHEGPGGGMGA-GGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHR-PHDV 864
             G  G R   GP G  G+ G    P  GP G+ G  GG  P   PG  GP G +     
Sbjct: 774 PPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGP---PGLSGPPGIKGEKGF 830

Query: 865 PGHRGHDHRGP 875
           PG  G D  GP
Sbjct: 831 PGFPGLDMPGP 841



 Score = 87.0 bits (214), Expect = 7e-17
 Identities = 102/319 (31%), Positives = 112/319 (35%), Gaps = 58/319 (18%)

Query: 622 PGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGPHGGPGGPVGPRLLGP------------ 669
           PGP  +  PPG PG   G+    PGP    PG  G PG P  P  +G             
Sbjct: 413 PGPPGSPGPPGQPGYTNGIVECQPGP----PGDQGPPGIPGQPGFIGEIGEKGQKGESCL 468

Query: 670 ---------PPPPRGGDPFWDGPGDP----MRGGPMRGG----PGPGPGPYHRGRGGRGG 712
                    PP P+G       PG P     RG P R G    PGP   P   G+ G  G
Sbjct: 469 ICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKG 528

Query: 713 NEPPPPPPPFRGARGGRSGGGPPNGRGGPG----GGMVGGGGHRPHEGPGGGMGNSSGHR 768
                 P  F      +   G P   G PG     G  G  GH    GP G  G S G +
Sbjct: 529 E-----PGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPG-SVGLK 582

Query: 769 PHEGPGGGMG-SGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGG 827
              GP GG+G  G R   GP G  G G      +    G  GG G     GP    G  G
Sbjct: 583 GERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGP---KGEPG 639

Query: 828 GHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPG 887
              P  GP G+ G  G       PG  GP G R     G  G   R   P E      PG
Sbjct: 640 KIVPLPGPPGAEGLPG------SPGFPGPQGDR-----GFPGTPGRPGLPGEKGAVGQPG 688

Query: 888 HGGGGHRGHDGGHSHGGDM 906
            G  G  G  G     GDM
Sbjct: 689 IGFPGPPGPKGVDGLPGDM 707



 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 130/435 (29%), Positives = 163/435 (37%), Gaps = 77/435 (17%)

Query: 539  PGGSG--GSPDGAGGSKLP--PVLANLMGSMGAG----KGPQG-PGGGGINVQEILTSIM 589
            PG  G  G+P   G + LP  P +    G  G G    KG  G PG  G   ++    + 
Sbjct: 704  PGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVP 763

Query: 590  GSPNSH-----PSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGP------- 637
            G P  H     P  + ++       +   +   G+ G GP     PPGG G P       
Sbjct: 764  GVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPG 823

Query: 638  -KGMQHFPPGPGGPMPGPHGGPGGPVGPRLLG----PPPPPRGGDPFWDG-PGDPMRGGP 691
             KG + FP  PG  MPGP G  G    P + G    P  P + G P   G PG     G 
Sbjct: 824  IKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGV 883

Query: 692  M-----RGGPGP--GPG-PYHRGRGGRGGNEPPPPPPPFRGARG-----GRSGG------ 732
            M      G PGP   PG P  +G  G  G+  P   P  +G +G     G+ G       
Sbjct: 884  MGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDM 943

Query: 733  GPPNGRGGPGG-----GMVGGGGHRPHEGPGG--GMGNSSGHRPHEGPGGGMGSGHRPH- 784
            G   G+ G  G     G +G  G R   G  G  G    +G     GP G  G    P  
Sbjct: 944  GSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGA 1003

Query: 785  ---EGPGGSMGGGG--------GHRPHEGPGG--GISGGSGHRPHEGPGGGMGAG-GGHR 830
                GP GS+GG G        G     GP G  G+ G  G +  +G  G  G G  G R
Sbjct: 1004 PGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLR 1063

Query: 831  PHEGPGGSMG--GSGGHRPHEG----PGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHD 884
              +G  G  G  GS G +  +G    PG  G  G +    PG  G+      P E     
Sbjct: 1064 GEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLK--GSPGSVGYPGSPGLPGEKGDKG 1121

Query: 885  GPGHGG-GGHRGHDG 898
             PG  G  G +G  G
Sbjct: 1122 LPGLDGIPGVKGEAG 1136



 Score = 82.4 bits (202), Expect = 2e-15
 Identities = 119/380 (31%), Positives = 141/380 (37%), Gaps = 51/380 (13%)

Query: 541  GSGGSPDGAGGSKLP--PVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
            GS G     G   +P  P    L GS G+   P  PG  G    + L  + G P      
Sbjct: 1076 GSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEA 1135

Query: 599  ELLKQPDYSDKIKQMLVP--HGLLG-------PGPIANGFP--PGGPG--GPKGMQHFPP 645
             L   P  +    Q   P   G+ G       PG    GFP  PG  G  G KG   FP 
Sbjct: 1136 GLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPG 1195

Query: 646  GPGGP-MPGPHG-----GPGGPVG-PRLLGPP----PPPRGGDPFWDGPGDPMRGGPMRG 694
              G P +PG  G     GP GP G P L G P      P+G       PG P   GPM  
Sbjct: 1196 LAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPM-- 1253

Query: 695  GPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG----GGMVGGGG 750
              GP   P   G  G  GN   P  P   G +G     G P   G PG     G +G  G
Sbjct: 1254 --GPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPG 1311

Query: 751  HRPHEGPGG--GMGNSSGHRPHEGPGGGMGSGHRPHE-GPGGSMGGGGGHRPHEGPGG-- 805
                +GP G  G+    G +  +G  G  G    P   GP   + G  G    EGP G  
Sbjct: 1312 VPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLK 1371

Query: 806  GISGGSGHRPHEGPGGGMGAGG-----GHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHR 860
            G+ G  G +  +G  G +G  G     G     G  G MG +G   P   PG  GP G  
Sbjct: 1372 GLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDG-- 1429

Query: 861  PHDVPGHRGHDHRGPPPHEH 880
               +PG  G    G P  +H
Sbjct: 1430 ---LPGSMGPP--GTPSVDH 1444



 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 121/397 (30%), Positives = 138/397 (34%), Gaps = 98/397 (24%)

Query: 628 GFP----PGGPGGPKGMQHFPPGPGGP-------MPGPHGGPGGPVGPRLL---GPPPPP 673
           GFP    P GP GP G +     PG P        PG  G PG P  P +    GPP PP
Sbjct: 61  GFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPP 120

Query: 674 -----------RG--GDP----FWDGPGDPMRGGPMRGGPG------PG---------PG 701
                      RG  G P    F   PG P   G M+G PG      PG         PG
Sbjct: 121 GIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPG-MKGDPGEILGHVPGMLLKGERGFPG 179

Query: 702 -PYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGG 760
            P   G  G  G + P  PP F G  G     GPP  +G  G    G  G +  +G  G 
Sbjct: 180 IPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGP 239

Query: 761 MG-------------NSSGHRPHEGPGG-----GMGSGHRPHE-GPGGSMGGGGGHRPHE 801
            G              + G +  +G  G     G+G    P + GP G  G  G      
Sbjct: 240 PGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKG 299

Query: 802 GPG-GGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSG--GHRPHEG-PGHGGPH 857
            PG  G  G  G    +GP G  G  G      GP G + G+G  G +   G PG  GP 
Sbjct: 300 SPGFPGEPGYPGLIGRQGPQGEKGEAG----PPGPPGIVIGTGPLGEKGERGYPGTPGPR 355

Query: 858 GH-RPHDVPGHRGHDHRGPPPHEHRGHDGPGHGGG----GHRGHDGGHSHGGDMSNRPVC 912
           G   P   PG  G    GPP     G   PG  G     G RG  G     G     P  
Sbjct: 356 GEPGPKGFPGLPGQP--GPP-----GLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSG 408

Query: 913 RHFM--------MKGNCRYEN---NCAFYHPGVNGPP 938
           R  +          G   Y N    C    PG  GPP
Sbjct: 409 RDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPP 445



 Score = 78.6 bits (192), Expect = 3e-14
 Identities = 133/458 (29%), Positives = 158/458 (34%), Gaps = 116/458 (25%)

Query: 539 PGGSGGSPDGAGGSKLP--PVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHP 596
           P G  G P   G +  P  P      G  GA   P  PG  GI  Q+      G P  + 
Sbjct: 68  PEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNG 127

Query: 597 SEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPG------------------GPK 638
           ++            +  L P GL  PG   N  PPG PG                  G +
Sbjct: 128 TKGE----------RGPLGPPGL--PGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGER 175

Query: 639 GMQHFPPGPGGP----MPGPHGGPG--GPVGPRLLGPPPPP----------------RGG 676
           G    P  PG P    + GP G PG  GP GP   GPP PP                +G 
Sbjct: 176 GFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPP--GPPGPPGEKGQMGLSFQGPKGDKGD 233

Query: 677 DPFWDGPGDP------------------MRGGP-MRGGPGPG-------PGPYHRGRGGR 710
                 PG P                   +G P  +G PG G       PGP  RG+ G+
Sbjct: 234 QGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGP--RGKPGK 291

Query: 711 GGNEPPPPPPPFRGARG-----GRSGGGPPNGRGGPGG--GMVGGGGHRPHEGPGGGMGN 763
            G++     P F G  G     GR G     G  GP G  G+V G G    +G  G  G 
Sbjct: 292 DGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPG- 350

Query: 764 SSGHRPHEGPGGGMGSGHRPHEGPG----GSMGGGG--GHRPHEG----PGGGISGGSGH 813
           + G R   GP G  G   +P   PG    G  G  G  G R  +G    PG  + G SG 
Sbjct: 351 TPGPRGEPGPKGFPGLPGQPGP-PGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGR 409

Query: 814 RPHEGPGGGMGAGG--GH-----RPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPH---- 862
               GP G  G  G  G+         GP G  G  G        G  G  G +      
Sbjct: 410 DGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLI 469

Query: 863 -DVPGHRGHDHRGPPPHEHRGHDGPG-HGGGGHRGHDG 898
            D+ G+RG      PP E      PG  G  G  G DG
Sbjct: 470 CDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDG 507



 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 125/406 (30%), Positives = 148/406 (36%), Gaps = 58/406 (14%)

Query: 541  GSGGSPDGAGGSKLPPVLANLMGSMG--AGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
            G  G P G  G +  P L    G+ G     GP G G  G+  ++    I G P S P E
Sbjct: 1023 GEKGVP-GIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGS-PGE 1080

Query: 599  ELLKQPDYSDKIKQMLVPHGLLG-PGPIANGFPPGGPG--GPKGMQHFPPGPGGPMPGPH 655
               K    S  I  M    GL G PG +     PG PG  G KG+    PG  G +PG  
Sbjct: 1081 ---KGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGL----PGLDG-IPGVK 1132

Query: 656  GGPGGPVGPRLLGPPPPPRGGDPFWDG----------PGDPMRGGPMRGGPGPGPGPYHR 705
            G  G P  P   GP    + G+P  DG          PG P RG P  G PG       +
Sbjct: 1133 GEAGLPGTPGPTGPAG--QKGEPGSDGIPGSAGEKGEPGLPGRGFP--GFPGAKGDKGSK 1188

Query: 706  GRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSS 765
            G  G  G    P  P  +G +G     GP    G PG       G +   GP G  G   
Sbjct: 1189 GEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPG 1248

Query: 766  GHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPG----GGISGGSGHRPHEGPGG 821
               P   PG     G +  +G  G  G  G   P   PG     GI G  G    +G  G
Sbjct: 1249 LPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMG 1308

Query: 822  GMGAGGGHRPHEGPG-----GSMGGSGGHRPHEGPGHGGPHGHRPHDV----PGHRGHDH 872
              G  G   P   PG     G  G  G       PG  GP G  P+D+    PG  G + 
Sbjct: 1309 PPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPG--PYDIIKGEPGLPGPE- 1365

Query: 873  RGPPPHEH-RGHDGPG-----------HGGGGHRGHDGGHSHGGDM 906
             GPP  +  +G  GP             G  G  G DG     G+M
Sbjct: 1366 -GPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEM 1410



 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 138/483 (28%), Positives = 165/483 (34%), Gaps = 136/483 (28%)

Query: 539 PGGSG--GSPD-----GAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGS 591
           PG SG  G+P      G  G   PP +    G+ G  +GP GP G        L    G+
Sbjct: 96  PGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGE-RGPLGPPG--------LPGFAGN 146

Query: 592 PNSHPSEELLKQP-DYSDKIKQMLVPHGLLGPGPIANGFPPGGPG--GPKGMQHF--PPG 646
           P       +   P +    +  ML+      PG      PPG PG  GP G   F  PPG
Sbjct: 147 PGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPG 206

Query: 647 PGGPMPGPHGGPG-------GPVGPR----LLGPPPPP------------------RGGD 677
           P GP PGP G  G       GP G +    + GPP  P                  + G+
Sbjct: 207 PPGP-PGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGE 265

Query: 678 PFWDG------PGDPMRGGPMRGGPG----------PG-PG-PYHRGRGGRGG-----NE 714
           P + G       G+P + GP RG PG          PG PG P + G  GR G      E
Sbjct: 266 PGFQGMPGVGEKGEPGKPGP-RGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGE 324

Query: 715 PPPPPPP----------------FRGARGGRSGGGP------PNGRGGPG------GGMV 746
             PP PP                + G  G R   GP      P   G PG       G  
Sbjct: 325 AGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAP 384

Query: 747 GGGGHRPHEG----PGGGMGNSSGHRPHEGPGGGMGSGHRP---------HEGPGGSMGG 793
           G  G R  +G    PG  +   SG     GP G  G   +P           GP G  G 
Sbjct: 385 GFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGP 444

Query: 794 GG-----------GHRPHEGPGGGISGGSGHRPHEGPGGGMGAGG-----GHRPHEGPGG 837
            G           G +  +G    I    G+R   GP G  G  G     G +   G  G
Sbjct: 445 PGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPG 504

Query: 838 SMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDG-PG-HGGGGHRG 895
             G +G   P   PG  G  G +    PG    D R        G  G PG  G  G  G
Sbjct: 505 RDGVAGVPGPQGTPGLIGQPGAKGE--PGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPG 562

Query: 896 HDG 898
            DG
Sbjct: 563 RDG 565



 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 87/277 (31%), Positives = 101/277 (36%), Gaps = 34/277 (12%)

Query: 633 GPGGPKGMQHFPPGPGGPMPGPHGGPG--GPVGPRLLGPPPPPRGGDPFWDGPGDPMRGG 690
           G  G KG +  P      + G  G PG  GP GP+     PP + GD     PG P   G
Sbjct: 43  GVKGQKGERGLPG-----LQGVIGFPGMQGPEGPQ----GPPGQKGDT--GEPGLPGTKG 91

Query: 691 PMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGG 750
             RG PG    P + G  G  G + PP PP   G  G +   GP    G P  G  G  G
Sbjct: 92  T-RGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLP--GFAGNPG 148

Query: 751 HRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGG--GHRPHEGPGGGIS 808
                G  G  G   GH P     G +  G R   G  G+ G  G  G +   GP  G +
Sbjct: 149 PPGLPGMKGDPGEILGHVP-----GMLLKGERGFPGIPGTPGPPGLPGLQGPVGP-PGFT 202

Query: 809 GGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHR 868
           G  G     GP G  G  G     +GP G  G  G   P   PG             G +
Sbjct: 203 GPPGPPGPPGPPGEKGQMG--LSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEK 260

Query: 869 GHDHRGPPPHEHRGHDG-PGHGGGGHRGHDGGHSHGG 904
           G   +G P     G  G PG G  G  G  G     G
Sbjct: 261 G--QKGEP-----GFQGMPGVGEKGEPGKPGPRGKPG 290



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 67/217 (30%), Positives = 77/217 (35%), Gaps = 17/217 (7%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQ------EILTSIMGSP 592
            P G  G P G  G   PP L  + G  G    P  PG  G+         + +  I GSP
Sbjct: 1240 PQGQPGLP-GLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSP 1298

Query: 593  NSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMP 652
                S+  +  P     +     P GL G   I       G  G KG+   PPGP GP  
Sbjct: 1299 GITGSKGDMGPPG----VPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPG-PPGPPGPYD 1353

Query: 653  GPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGG 712
               G PG P GP      PP   G     GP        + G PGP   P   G  G+ G
Sbjct: 1354 IIKGEPGLP-GPE----GPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKG 1408

Query: 713  NEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGG 749
               P  P   RG  G     G P   G PG   V  G
Sbjct: 1409 EMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSVDHG 1445


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  106 bits (264), Expect = 1e-22
 Identities = 153/483 (31%), Positives = 181/483 (37%), Gaps = 84/483 (17%)

Query: 470  PSPLVTPGSNSQERYIQAEREKGILQELFL----NKESPHEPDPEPYEPIPPKLIPLDEE 525
            P P   PG   Q   I     KG + ++        E P  P   P +P  P L P  + 
Sbjct: 1005 PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGL-PGQKG 1063

Query: 526  CSMDETPYVETL----------EPG--GSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQG 573
               D  P + ++          EPG  G  G+P G  GS   P L  L G+ GA KG  G
Sbjct: 1064 DKGD--PGISSIGLPGLPGPKGEPGLPGYPGNP-GIKGSVGDPGLPGLPGTPGA-KGQPG 1119

Query: 574  ----------PGGGGINVQEILTSIMGSPN-----SHPSEELLKQPDYSDKIKQMLVP-- 616
                      PG  GI+       + G P       HP +     P    K  Q  +P  
Sbjct: 1120 LPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQP--GPPGEKGKPGQDGIPGP 1177

Query: 617  ---HGLLGPGPIANGFPPGGPG--GPKGMQHFPPGPGGP-MPGPHGGPGGPVGPRLLGPP 670
                G  G     N  PPG PG  G KG    P  PG P +PGP G PG    P + GPP
Sbjct: 1178 AGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPP 1237

Query: 671  PPPRGGDPFWDGP-------GDPMRGGP--MRGGPGPGPGPYHRGRGGRGGNEPPPPPPP 721
             PP    P  +GP       G P R GP   +G PGP   P   G GG  G +  P  P 
Sbjct: 1238 GPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPG 1297

Query: 722  FRGARGGRSGGGPPNGRGGPGG-GMVGGGGHRPHEGPGG--GMGNSSGHRPHEGPGGGMG 778
              G  G +   GPP  +G PG  G+ G  G     G  G  GM   SG     GP G  G
Sbjct: 1298 LPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPG 1357

Query: 779  SGHRPHEGPGGSMGGGGGHRPHEGPGG--GISGGSGHRPHEGPGGGMGAGGGHRPHEGPG 836
                P  GP G  G  G     +G  G  GI G  G +   GP G  G  G      GP 
Sbjct: 1358 LIGPP--GPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGP----TGPP 1411

Query: 837  GSMGGSGGHRPHEGPGHGGPHGHRPHD-VPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRG 895
            G  G +G       PG  G  G +    +PG  G           RG DGP  G  G +G
Sbjct: 1412 GDPGRNGL------PGFDGAGGRKGDPGLPGQPGT----------RGLDGP-PGPDGLQG 1454

Query: 896  HDG 898
              G
Sbjct: 1455 PPG 1457



 Score =  103 bits (256), Expect = 1e-21
 Identities = 141/443 (31%), Positives = 166/443 (37%), Gaps = 94/443 (21%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQG----PGGGGINVQEILTSIMGSPNS 594
            P G+ G P G  G   PP L   +G MG   GPQG    PG  G+  Q       GSP  
Sbjct: 1007 PKGNPGLP-GQPGLIGPPGLKGTIGDMGF-PGPQGVEGPPGPSGVPGQP------GSPGL 1058

Query: 595  HPSEELLKQPDYSDKIKQMLVPHGLLG-PGPIANGFPPGGPGGP--KGMQHFPPGPGGP- 650
             P ++        DK    +   GL G PGP      PG PG P  KG    P  PG P 
Sbjct: 1059 -PGQK-------GDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPG 1110

Query: 651  MPGPHGGPGGPVGPRLLGPPPPPR----GGDPFWDGPGDPMRGGPMRGGPGPG------- 699
             PG  G PG P  P   GPP P       G+P   G   P+ GG   G PGP        
Sbjct: 1111 TPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPG 1170

Query: 700  ----PGPY-HRGRGGRGG-NEPPPPPPPFRGARGGRSGGGPPNGRGGPG-------GGMV 746
                PGP   +G  G+ G   P PP  P  G  G +  GG P   G PG        G  
Sbjct: 1171 QDGIPGPAGQKGEPGQPGFGNPGPPGLP--GLSGQKGDGGLPGIPGNPGLPGPKGEPGFH 1228

Query: 747  GGGGHRPHEGPGGGMGNS-SGHRPHEGPGGGMG----SGHRPHEGPGGSMG--GGGGHRP 799
            G  G +   GP G  G +  G + + GP G  G    +G +   GP G  G  G GG + 
Sbjct: 1229 GFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKG 1288

Query: 800  HEGPGG--GISGGSGHRPHEGPGGGMGAGG-----GHRPHEGPGGSMGGSGGHRPHEGPG 852
             +G  G  G+ G  G +  +GP G  G  G     G +   G  G  G  G   P   PG
Sbjct: 1289 EKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPG 1348

Query: 853  HGGPHGH-------RPHDVPGHRGHD-----HRGPP-------------PHEHRGHDGP- 886
              GP G         P  +PG  G         GPP             P   +G  GP 
Sbjct: 1349 SAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPT 1408

Query: 887  ----GHGGGGHRGHDGGHSHGGD 905
                  G  G  G DG     GD
Sbjct: 1409 GPPGDPGRNGLPGFDGAGGRKGD 1431



 Score = 98.2 bits (243), Expect = 3e-20
 Identities = 127/372 (34%), Positives = 145/372 (38%), Gaps = 63/372 (16%)

Query: 539 PGGSG--GSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHP 596
           PG  G  GS    G     P +    G +G+   P  PG  G   Q+ L  + G P   P
Sbjct: 535 PGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPG-PKGEP 593

Query: 597 SEELLKQPDYSDKIKQMLVPHGLLGP-GPIANGFPPGGPGGPKGMQHFPPGPGGP-MPGP 654
                K          +    G +GP GP   GF P GP G KG+Q     PG P +PGP
Sbjct: 594 GGITFKGERGPPGNPGLPGLPGNIGPMGP--PGFGPPGPVGEKGIQGVAGNPGQPGIPGP 651

Query: 655 HGGPG------------------GPVG----PRLLGPPP----PPRGGDPFWDGPGDPMR 688
            G PG                  G VG    P L G P     P   G+P   G G P  
Sbjct: 652 KGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP 711

Query: 689 GGPMRGGPG-PGPGPYHRGRGGRGGNEPPPPPPPFRGARG--GRSGGGPPNGRGGPG-GG 744
            GP +G PG PGP P   G  GR G E PP PP F G +G  G +  GPP   G PG  G
Sbjct: 712 PGP-KGFPGIPGP-PGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG 769

Query: 745 MVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEG-- 802
            +G  G R   GP              GP G  G    P  GP G +G  G   P     
Sbjct: 770 ALGPKGDRGFPGP-------------PGPPGRTGLDGLP--GPKGDVGPNGQPGPMGPPG 814

Query: 803 -PGGGISGGSGHRPHEGPGGGMGAGG--GHRPHEGPGG-SMGGSGGHRPHEG-PGHGGPH 857
            PG G+ G  G     GP G  G  G  G +   GP G  + G  G R   G PG  GP 
Sbjct: 815 LPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPI 874

Query: 858 GHRPHDVPGHRG 869
           G  P   PG  G
Sbjct: 875 G--PPGSPGLPG 884



 Score = 97.4 bits (241), Expect = 5e-20
 Identities = 166/532 (31%), Positives = 188/532 (35%), Gaps = 143/532 (26%)

Query: 538  EPGGSG----------GSP--DGAGGSKLPPVLANLMGSMGAG-----------KGPQGP 574
            +PG  G          GSP   GA G   PP    L G  GA             GP GP
Sbjct: 847  DPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGP 906

Query: 575  GGG-GINVQEILTSIMGSPNSHPSEELLKQPDYSDKI--KQMLVPHGLLG-PGPI----- 625
             G  GI  +       G P     + L  QP        K      GL G PGP+     
Sbjct: 907  PGPLGIPGRS------GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960

Query: 626  ----ANGFP--PGGPG--GPKGMQHFPPGPGGP----------MPGPHGGPGGPVGPRLL 667
                  G P  PG PG  GPKG Q  P  PG P           PGP G PG P  P L+
Sbjct: 961  GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI 1020

Query: 668  GPP-----------PPPRG--------------------------GDPFWDGPGDPMRGG 690
            GPP           P P+G                          GDP     G P   G
Sbjct: 1021 GPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG 1080

Query: 691  PMRGGPG-PG-PG----------PYHRGRGGRGGNEPPPPPPPFRGARG--GRSG-GGPP 735
            P +G PG PG PG          P   G  G  G +  P  P F G  G  G  G  GPP
Sbjct: 1081 P-KGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPP 1139

Query: 736  NGRGGPG-GGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRP---HEGPGGSM 791
               G PG  G VGGGGH    GP G  G   G     GP G  G   +P   + GP G  
Sbjct: 1140 GNPGLPGEPGPVGGGGHPGQPGPPGEKG-KPGQDGIPGPAGQKGEPGQPGFGNPGPPGLP 1198

Query: 792  GGGGGHRPHEGPGG--GISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGS-----GG 844
            G  G     +G GG  GI G  G    +G  G  G  G   P  GP GS G +     G 
Sbjct: 1199 GLSG----QKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGP-PGPPGSPGPALEGPKGN 1253

Query: 845  HRPHEGPGHGGPHGHR-------PHDVPGHRG-HDHRGPPPHEH-------RGHDGPGHG 889
              P   PG  GP G +       P  +PG+ G    +G P           +G  GP  G
Sbjct: 1254 PGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGP-PG 1312

Query: 890  GGGHRGHDGGHSHGGDMSNRPVCRHFMMKGNCRYENNCA-FYHPGVNGPPLP 940
              G+ G  G +   GD     V     MKG      +      PG+ GPP P
Sbjct: 1313 LQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1364



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 92/274 (33%), Positives = 105/274 (38%), Gaps = 31/274 (11%)

Query: 633 GPGGPKGMQHFPPGPGGP-MPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDG-PGDPMRGG 690
           G  G KG + FP   G P +PG   GP GP GPR          G    DG PG P   G
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPG-FPGPEGPPGPR----------GQKGDDGIPGPPGPKG 90

Query: 691 PMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG-GGMVGGG 749
            +RG PG    P   G  G  G++  P P    G  G +   G P   G PG  G  G  
Sbjct: 91  -IRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPP 149

Query: 750 GHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISG 809
           G    +G  G +  SS   P   PG     G +   GP G  G  G   P      G+ G
Sbjct: 150 GIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGP-----PGLMG 204

Query: 810 GSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRG 869
             G     GP G MG        +GP G  G  G   P   PG       RP DV   +G
Sbjct: 205 PPGPPGLPGPKGNMGLN-----FQGPKGEKGEQGLQGPPGPPGQISEQ-KRPIDVEFQKG 258

Query: 870 HD----HRGPP-PHEHRGHDGPGHGGGGHRGHDG 898
                  RGPP P   RG  GP  G  G +G  G
Sbjct: 259 DQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQG 292



 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 132/435 (30%), Positives = 159/435 (36%), Gaps = 80/435 (18%)

Query: 539 PGGSG-GSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQ-----EILTSIMGSP 592
           PG  G   P G  G   PP    LMG  G    P   G  G+N Q     +    + G P
Sbjct: 179 PGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPP 238

Query: 593 NSHPSEELLKQP-DYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGM--QHFPPGPGG 649
                    K+P D   +     +P     PGP     PPG PGG KG   +   PG  G
Sbjct: 239 GPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRG 298

Query: 650 PMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGP--MRGGPGPGPGP----- 702
             PG  G  G P      G P  P  GDP +  PG+P R G    +G  GP PGP     
Sbjct: 299 -KPGKDGENGQP------GIPGLP--GDPGY--PGEPGRDGEKGQKGDTGP-PGPPGLVI 346

Query: 703 YHRGRG---GRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGG---------GMVGGGG 750
              G G   G  GN   P  P  +G RG     GPP   G PG          G  G  G
Sbjct: 347 PRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERG 406

Query: 751 HRPHEGPGG-------GMGNSSGHRPHEGPGGGMGSGHRPHE--------GPGGSMGGGG 795
            +  EGP G       G+    G     GP G  G    P +        GP GS G  G
Sbjct: 407 QKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKG 466

Query: 796 --GHRPHEGP---------GGGISGGSGHRPHEGPGGGMGAGG--GHRPHEGPGGSMGGS 842
             G +  +G          G GISG  G     G  G  G+ G  G +  +G  G+ G  
Sbjct: 467 LQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPK 526

Query: 843 GGHRPHEGPGHGGPHGHR--PHDV---PGHRGH--DHRGPPPHEHRGHDG-PGHGG---- 890
           G       PG  G  G +  P D+   PG +G   +   P      G  G PG  G    
Sbjct: 527 GLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGL 586

Query: 891 GGHRGHDGGHSHGGD 905
            G +G  GG +  G+
Sbjct: 587 PGPKGEPGGITFKGE 601



 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 101/341 (29%), Positives = 120/341 (35%), Gaps = 66/341 (19%)

Query: 616 PHGLLGPGPIANGFPPGGPG--GPKGMQHFPPGPGGPMPGPHG-----------GPGGPV 662
           P GL GP   A   PPG PG  G +G +     PG  +PGP G           GP GP 
Sbjct: 381 PPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA 440

Query: 663 GPRL--------LGPPPPPRG----------------GDPFWDGPGDPMRGGPMRGG-PG 697
           GP +         GPP PP                  GD  ++  G  + G P + G PG
Sbjct: 441 GPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPG 500

Query: 698 -PGPG-----PYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGG-----GMV 746
            PGP      P  +G  G+ G   P   P   GA G     G P  +G PG      GM 
Sbjct: 501 LPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPG---APGFPGSKGEPGDILTFPGMK 557

Query: 747 GGGGHRPHEGPGG--GMGNSSGH-------RPHEGPGGGMGSGHRPHEGPGGSMGGGGGH 797
           G  G     G  G  G+  + G         P   PGG    G R   G  G  G  G  
Sbjct: 558 GDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNI 617

Query: 798 RPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPH 857
            P   PG G  G  G +  +G  G  G  G   P   PG ++   G       PG  G  
Sbjct: 618 GPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDV 677

Query: 858 GHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDG 898
           G     +PG  G   +   P        PG  G G  G  G
Sbjct: 678 G-----LPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPG 713



 Score = 77.4 bits (189), Expect = 6e-14
 Identities = 109/354 (30%), Positives = 125/354 (35%), Gaps = 71/354 (20%)

Query: 616 PHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGP-------MPGP------------HG 656
           P G  G   I     P G  GP G+  FP  PG P        PGP             G
Sbjct: 73  PRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERG 132

Query: 657 GPGGPVGPRLLGPPPPP----RGGDP------FWDGP-GDPMRGGP--MRGGPGPGPGPY 703
            PG P  P L GPP PP      G+P         GP G+P   GP  ++G PGP   P 
Sbjct: 133 FPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPG 192

Query: 704 HRGRGGRGGNEPPPPPPPFRGARG--GRSGGGPPNGRG-----GPGG------------- 743
             G  G  G   PP PP   G +G  G +  GP   +G     GP G             
Sbjct: 193 PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252

Query: 744 -----GMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGS-GHRPHEGPGGSMGGGGGH 797
                G  G  G R   GP G  G        +G  G  G  G R   G  G  G  G  
Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312

Query: 798 RPHEGPG-GGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGP 856
                PG  G  G  G +  +G  G  G  G   P  G G ++G  G       PG  G 
Sbjct: 313 GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372

Query: 857 HG----HRPHDVPGHRGHDHRGPP-----PHE--HRGHDG-PGHGGGGHRGHDG 898
            G      P  +PG  G    GPP     P E   +G +G PG    G  G DG
Sbjct: 373 RGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG 426



 Score = 77.0 bits (188), Expect = 8e-14
 Identities = 134/459 (29%), Positives = 162/459 (35%), Gaps = 141/459 (30%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMGAG-----KGPQGPGGGGINVQEILTSIMGSPN 593
            PG  G       G   PP L    G++G        GP GP G         T + G P 
Sbjct: 745  PGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGR--------TGLDGLPG 796

Query: 594  SHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPG----GPKGMQHFPPGPGG 649
                             K  + P+G   PGP+    PPG PG    GP G    PPG  G
Sbjct: 797  P----------------KGDVGPNGQ--PGPMG---PPGLPGIGVQGPPG----PPGIPG 831

Query: 650  PM--PGPHGGPG---GPVGPRLLGPPPPPRGGDPFWDG----------PGDPMRGGP--- 691
            P+  PG HG PG    P  P L  P PP   G P   G          PG P + G    
Sbjct: 832  PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGF 891

Query: 692  --------MRGGPGPGPGPYH----------RGRGGRGGNEPPPPPPPFRGARGGRSGGG 733
                    M G PGP PGP            +G  G  G    P P   +G++G     G
Sbjct: 892  PGTKGEMGMMGPPGP-PGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPG 950

Query: 734  PP-----------NGRGGPG-GGMVGGGGHRPHEGPGG--GMGNSSGHRPHEGPGGGMGS 779
            PP             +G PG  G+ G  G + ++G  G  G    SG     GP G  G+
Sbjct: 951  PPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN 1010

Query: 780  GHRPHE----GPGGSMG-----GGGGHRPHEGPGG--GISGGSGHRPHEGPGGGMGAGG- 827
               P +    GP G  G     G  G +  EGP G  G+ G  G     G  G  G  G 
Sbjct: 1011 PGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI 1070

Query: 828  ------------------GHRPHEGPGGSMG--------GSGGHRPHEG-PGHGGPHGHR 860
                              G+  + G  GS+G        G+ G +   G PG  G  G  
Sbjct: 1071 SSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPG-- 1128

Query: 861  PHDVPGHRGHDHRGPPPHEH-RGHDGPGHGGGGHRGHDG 898
                PG +G    GPP +    G  GP  GGGGH G  G
Sbjct: 1129 ---PPGPKGIS--GPPGNPGLPGEPGP-VGGGGHPGQPG 1161



 Score = 70.9 bits (172), Expect = 5e-12
 Identities = 94/307 (30%), Positives = 107/307 (34%), Gaps = 78/307 (25%)

Query: 539  PGGSGGSPDGAG-GSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPS 597
            P G  G P   G G+  PP L  L G  G G  P  PG  G      L    G P  H  
Sbjct: 1177 PAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPG------LPGPKGEPGFHGF 1230

Query: 598  EELLKQPDYSDKIKQMLVPHGLLGP---GPIANGFPPGGPG--GPKGMQHFPPGPGGP-- 650
              +   P           P G  GP   GP  N  P G PG  GP G Q  P GP GP  
Sbjct: 1231 PGVQGPPG----------PPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLP-GPEGPPG 1279

Query: 651  ------MPGPHGGPGGPVGPRLLG-----PPPPPRG-----------GDPFWDG-PGDPM 687
                  + G  G PG P  P L G      PP  +G           GDP   G PG P 
Sbjct: 1280 LPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPG 1339

Query: 688  RGGP--------------MRGGPGPG--PGPYHRGRGGRGGNEPP--PPPPPFRGARGGR 729
              GP              + G PGP   PGP  +    +G   PP  P  P  +G  G +
Sbjct: 1340 MKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQ 1399

Query: 730  SGGGPPNGRGGPGG-------GMVGGGGHRPHEGPGG-----GMGNSSGHRPHEGPGGGM 777
               G P   G PG        G  G GG +   G  G     G+    G    +GP G  
Sbjct: 1400 GPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPP 1459

Query: 778  GSGHRPH 784
            G+    H
Sbjct: 1460 GTSSVAH 1466



 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 79/247 (31%), Positives = 90/247 (36%), Gaps = 58/247 (23%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGP----GGGGINVQEILTSIMGSPNS 594
            PG +   P G  G + PP      G  G   GP+GP    G GGI  ++      G+P  
Sbjct: 1243 PGPALEGPKGNPGPQGPPGRPGPTGFQGL-PGPEGPPGLPGNGGIKGEK------GNPGQ 1295

Query: 595  HPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPG--GPKGMQHFPPGPGGP-M 651
                 L         +K    P GL G         PG PG  G KG    P  PG P M
Sbjct: 1296 PGLPGL-------PGLKGDQGPPGLQGN--------PGRPGLNGMKGDPGLPGVPGFPGM 1340

Query: 652  PGPHGGPG--GPVG-PRLLGPPPPPRGGDPFWDG------------PGDP-MRGGPMRGG 695
             GP G PG  GP G P L+GPP PP    P                PG P ++G P   G
Sbjct: 1341 KGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQG 1400

Query: 696  PGPGPGPY-------------HRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG 742
            P   PGP                G GGR G+   P  P  RG  G     G     G PG
Sbjct: 1401 PQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460

Query: 743  GGMVGGG 749
               V  G
Sbjct: 1461 TSSVAHG 1467


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  105 bits (263), Expect = 2e-22
 Identities = 136/432 (31%), Positives = 158/432 (36%), Gaps = 73/432 (16%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMG--AGKGPQGPGGG-GINVQEILTSIMG--SPN 593
            P G  G P G  G + P  +    G  G   G GP GP G  G N  +  T   G   P 
Sbjct: 908  PRGQRG-PTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPP 966

Query: 594  SHPSEELLK-------QPDYSDKIKQMLVPHGLLGP-GPIANGFPPG-----GPGGPKGM 640
              P ++ L        +  +  K      P G++GP GP     P G     GP GP G 
Sbjct: 967  GPPGKDGLPGHPGQRGETGFQGKTGPP-GPPGVVGPQGPTGETGPMGERGHPGPPGPPGE 1025

Query: 641  QHFP-----------PGPGGPMPGPHGGPG-----------GPVGPRLL----GPPPPPR 674
            Q  P           PGP G +PG  G PG           GPVG   L    GPP PP 
Sbjct: 1026 QGLPGLAGKEGTKGDPGPAG-LPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPG 1084

Query: 675  -GGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGG 733
              G P   GP        + G PGP   P   G  G  G + P  P    G +G     G
Sbjct: 1085 PAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPG 1144

Query: 734  PPNGRGGPG----GGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMG-SGHRPHEGPG 788
            P    G PG     G +G  G +  +G  G  G      P +GP G  G SG     GP 
Sbjct: 1145 PAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGP-QGPIGQPGPSGADGEPGPR 1203

Query: 789  GSMG-----GGGGHRPHEGPGG-----GISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGS 838
            G  G     G  G R   GP G     G+ G  G +   G  G MG  G   P  GP G+
Sbjct: 1204 GQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGP-RGPSGA 1262

Query: 839  MGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGH----DHRGPP-PHEHRGHDGPGHGGGGH 893
             G  G   P  G G+ G  G +    PG  G        GPP P   RG  G   G  G 
Sbjct: 1263 PGADGPQGPPGGIGNPGAVGEKGE--PGEAGEPGLPGEGGPPGPKGERGEKGES-GPSGA 1319

Query: 894  RGHDGGHSHGGD 905
             G  G     GD
Sbjct: 1320 AGPPGPKGPPGD 1331



 Score =  104 bits (260), Expect = 3e-22
 Identities = 153/459 (33%), Positives = 170/459 (37%), Gaps = 95/459 (20%)

Query: 502  ESPHEPDPEPYEPIPPKLIPLDEECSMDETPYVETLEPGGSGG-SPDGAGGSKLPPVLAN 560
            E  H  DP P  P  P     +     +  P     EPG  G   P G  G   PP +  
Sbjct: 641  EKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTG 700

Query: 561  LMGSMG--AGKGPQG-PGGGGINVQEILTSIMGSPNSHPSEELLKQPDYSDKIKQMLVPH 617
            + G  G     GPQG PG  G                +P  + L  P  +        P 
Sbjct: 701  MDGQPGPKGNVGPQGEPGPPG-------------QQGNPGAQGLPGPQGAIGPPGEKGPL 747

Query: 618  GLLG-PG-PIANGFPPGGPG-----GPKGMQHFPPGPGGPM--PGPHGGPG--------- 659
            G  G PG P A+G PPG PG     G KG Q  PPGP GP+  PGP G  G         
Sbjct: 748  GKPGLPGMPGADG-PPGHPGKEGPPGEKGGQG-PPGPQGPIGYPGPRGVKGADGIRGLKG 805

Query: 660  -----------------GPVGPRLLGPPPPPRGGDPFWDGPGDPM-RGGPMRGGPGP--G 699
                             G  G R    PP PRG D    GP  P  RGGP  G PGP   
Sbjct: 806  TKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGED----GPEGPKGRGGP-NGDPGPLGP 860

Query: 700  PG----------PYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGG-GMVGG 748
            PG          P + GR G  G+   P  P   G +GGR   G P  RG  G  G  G 
Sbjct: 861  PGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGE 920

Query: 749  GGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPG-GGI 807
             G R   G  G  GNS G    +GP G  G       GP G  G  G   P   PG  G 
Sbjct: 921  RGPRGITGKPGPKGNSGG----DGPAGPPGE-----RGPNGPQGPTGFPGPKGPPGPPGK 971

Query: 808  SGGSGHRPHEGPGGGMGAGGGHRPH--EGPGGSMGGSG--GHRPHEGPGHGGPHGHRPHD 863
             G  GH    G  G  G  G   P    GP G  G +G  G R H GP   GP G +   
Sbjct: 972  DGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGP--PGPPGEQ--G 1027

Query: 864  VPGHRGHD--HRGPPPHEHRGHDGPG--HGGGGHRGHDG 898
            +PG  G +     P P    G DGP    G  G RG  G
Sbjct: 1028 LPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPG 1066



 Score =  104 bits (260), Expect = 3e-22
 Identities = 125/377 (33%), Positives = 140/377 (37%), Gaps = 91/377 (24%)

Query: 539  PGGSGGSPD-GAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPS 597
            PG  G + D G  G   PP      G+ GA  GPQGP GG           +G+P +   
Sbjct: 1236 PGEKGETGDVGQMGPPGPPGPRGPSGAPGAD-GPQGPPGG-----------IGNPGA--- 1280

Query: 598  EELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPG-----------------GPGGPKGM 640
                        + +   P     PG    G PPG                 GP GPKG 
Sbjct: 1281 ------------VGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKG- 1327

Query: 641  QHFPPGPGGPM--PGPHGGPGGPVGPRLLGP-----PPPPRGGDPFWDGPGDPMRGGPMR 693
               PPG  GP   PGP G PG P  P   GP     PP  +G D     PG     GP  
Sbjct: 1328 ---PPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDD---GEPGQTGSPGPT- 1380

Query: 694  GGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRG--GPGG--GMVGGG 749
            G PGP   P  RG  G  G   P      +GA+G     GPP   G  GP G  G  G  
Sbjct: 1381 GEPGPSGPPGKRGPPGPAG---PEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPD 1437

Query: 750  GHRPHEGPGGGMGNSSGHRPHEGPGGGMGS----GHRPHEGPGGSMGGGG---------- 795
            G R   GP G  G      P +GP G MG     G +   GP G  G  G          
Sbjct: 1438 GLRGIPGPVGEQGLPGSPGP-DGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGE 1496

Query: 796  ----GHRPHEGPGGGISGGSGHRPHEGPGGGMGAGG--GHRPHEGPGGSMGGSGGHRPHE 849
                G R   GP G  SG  G +   GP G +G  G  G     GP G+ G SG   P  
Sbjct: 1497 QGEKGDRGLPGPQGS-SGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKG 1555

Query: 850  GPGHGGPHGHRPHDVPG 866
              GH GP G  P   PG
Sbjct: 1556 EAGHPGPPG--PPGPPG 1570



 Score =  103 bits (256), Expect = 1e-21
 Identities = 139/406 (34%), Positives = 158/406 (38%), Gaps = 84/406 (20%)

Query: 541  GSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPN--SHPSE 598
            G  G P   G   LP     L G  G  KG  GP G        L    G P     P +
Sbjct: 1015 GHPGPPGPPGEQGLP----GLAGKEGT-KGDPGPAG--------LPGKDGPPGLRGFPGD 1061

Query: 599  ELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGPHG-- 656
              L  P  +  +K    P G  GP        P G  GP G+    PGP GP PGP G  
Sbjct: 1062 RGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPG-RPGPQGP-PGPAGEK 1119

Query: 657  ------GPGGPVGPRLLGPP---PPPRG--GDPFWDGP----GDPMRGGPM-----RGGP 696
                  GP GP G   L  P   P P G  G P  DG     G+P + G       +G P
Sbjct: 1120 GAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPP 1179

Query: 697  GP-GP-GPYHRGRGGRGGNEPPPPPPPFRGARG--GRSGGGPPNGRGGPGG-----GMVG 747
            GP GP GP   G+ G  G +  P P   RG +G  G+ G   P G  GP G     G+ G
Sbjct: 1180 GPTGPQGPI--GQPGPSGADGEPGP---RGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPG 1234

Query: 748  GGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGG-----GHRPHEG 802
              G +   G  G MG      P  GP G  G+     +GP G  GG G     G +   G
Sbjct: 1235 PPGEKGETGDVGQMGPPGPPGPR-GPSGAPGA-----DGPQGPPGGIGNPGAVGEKGEPG 1288

Query: 803  ----PG----GGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHG 854
                PG    GG  G  G R  +G  G  GA G   P +GP G  G  G   P   PG  
Sbjct: 1289 EAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGP-KGPPGDDGPKGSPGPVGFPGDP 1347

Query: 855  GPHGHRPHDVPGHRGHDHRGPPPHEHRGHDG-PGH-GGGGHRGHDG 898
            GP G      PG  G D  GPP    +G DG PG  G  G  G  G
Sbjct: 1348 GPPGE-----PGPAGQD--GPP--GDKGDDGEPGQTGSPGPTGEPG 1384



 Score =  102 bits (254), Expect = 2e-21
 Identities = 133/407 (32%), Positives = 160/407 (39%), Gaps = 79/407 (19%)

Query: 536 TLEPGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGP--------GGGGINVQEILTS 587
           T+ P G  G P    G + PP    L G+ G   GP G         GGGG    +    
Sbjct: 485 TMGPTGQVGDP----GERGPPGRPGLPGADGL-PGPPGTMLMLPFRFGGGGDAGSK---G 536

Query: 588 IMGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLG-PGPIANGFPPGGPGGPKGMQHFPPG 646
            M S     ++ +L+Q   +  ++    P GL G PGP+       GP G  G++   PG
Sbjct: 537 PMVSAQESQAQAILQQARLA--LRGPAGPMGLTGRPGPV-------GPPGSGGLKG-EPG 586

Query: 647 PGGPMPGPHG--GPGGPVGPRLLGPPPPPRGGDPFWDGP-GDPMRGGPM--RGGPGPGPG 701
             GP  GP G  GP GP G        P R G    DG  G P + GP   RG  G    
Sbjct: 587 DVGPQ-GPRGVQGPPGPAG-------KPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGL 638

Query: 702 PYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG-GGMVGGGGHRPHEGPGG- 759
           P  +G  G  G   PP PP   G RG     GP    G PG  G++G  G     GP G 
Sbjct: 639 PGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGV 698

Query: 760 -GMGNSSGHRPHEGPGGGMG-------SGHRPHEGPGGSMGGGGGHRPHEGPG----GGI 807
            GM    G + + GP G  G        G +   GP G++G  G   P   PG     G 
Sbjct: 699 TGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGA 758

Query: 808 SGGSGHRPHEGPGGGMGAGGGHRP-----HEGPGGSMGGSG--------GHRPHEG-PGH 853
            G  GH   EGP G  G  G   P     + GP G  G  G        G +  +G PG 
Sbjct: 759 DGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGF 818

Query: 854 GGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGP--GHGGGGHRGHDG 898
            G  G     + G RG    GPP    RG DGP    G GG  G  G
Sbjct: 819 KGDMG-----IKGDRG--EIGPP--GPRGEDGPEGPKGRGGPNGDPG 856



 Score =  100 bits (249), Expect = 6e-21
 Identities = 138/459 (30%), Positives = 165/459 (35%), Gaps = 104/459 (22%)

Query: 547 DGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGI----------NVQEILTSIMGSPNSHP 596
           D   G+++P   A+   S      P G G   +          N+ E        P S P
Sbjct: 369 DPGAGAEIPTSTADTSNSSNPAP-PPGEGADDLEGEFTEETIRNLDENYYDPYYDPTSSP 427

Query: 597 SEELLKQPDYSDKIKQMLV-PHGLLG----PGPIANGFPPGGPGGPKGMQHF--PPGPGG 649
           SE     P   D I + +  P G  G    P  I  G    GP GP+G      PPG  G
Sbjct: 428 SEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMG 487

Query: 650 PM-----PGPHGGPGGPVGPRLLGPPPPP-----------RGGDPFWDGP---------- 683
           P      PG  G PG P  P   G P PP            GGD    GP          
Sbjct: 488 PTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQ 547

Query: 684 ------GDPMRG--GPM--RGGPGPGPGPYHRGRGGRGGNEPP--------PPPPPFRGA 725
                    +RG  GPM   G PGP   P   G  G  G+  P        PP P  +  
Sbjct: 548 AILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPG 607

Query: 726 RGGRSGG----------GPPNGRGGPG-GGMVGGGGHRPHEGPGG--GMGNSSGHRPHEG 772
           R GR+G           GP   RG  G  G+ G  GHR   GP G  G     G R  +G
Sbjct: 608 RRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDG 667

Query: 773 PGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPG-GGISGGSGHRPHEGPGGGMGAGG---- 827
             G  G    P  GP G +G  G   P   PG  G+ G  G + + GP G  G  G    
Sbjct: 668 EVGPRGLPGEP--GPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGN 725

Query: 828 -GHRPHEGPGGSMGGSGGHRP------HEGPGHGGPHGHRPHD-VPGHRGHDHRGPP-PH 878
            G +   GP G++G  G   P         PG  GP GH   +  PG +G   +GPP P 
Sbjct: 726 PGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKG--GQGPPGPQ 783

Query: 879 EHRGHDGPG-----------HGGGGHRGHDGGHSHGGDM 906
              G+ GP             G  G +G DG     GDM
Sbjct: 784 GPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDM 822



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 72/223 (32%), Positives = 82/223 (36%), Gaps = 46/223 (20%)

Query: 464  PRPLVLPSPLVTPGSNSQERYIQAER---EKGILQELFLN----KESPHEPDPEPYEPIP 516
            P P   P P   PG          E    EKG   E  L     K  P  P   P +P P
Sbjct: 1377 PGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGP 1436

Query: 517  PKLIPLDEECSMDETPYVETLEPGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGG 576
              L  +         P  E   PG  G  PDG  G   PP L  L G  G  KG +G  G
Sbjct: 1437 DGLRGIPG-------PVGEQGLPGSPG--PDGPPGPMGPPGLPGLKGDSGP-KGEKGHPG 1486

Query: 577  GGINVQEILTSIMGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGG 636
                    L  ++G P         +Q +  D+   +  P G  GP        P GP G
Sbjct: 1487 --------LIGLIGPPG--------EQGEKGDR--GLPGPQGSSGPKGEQGITGPSGPIG 1528

Query: 637  PKGMQHFPPGPGGPMPGPHGGPG--GPVGPR----LLGPPPPP 673
            P G    PPG  GP PGP G  G  GP GP+      GPP PP
Sbjct: 1529 PPG----PPGLPGP-PGPKGAKGSSGPTGPKGEAGHPGPPGPP 1566



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 86/331 (25%), Positives = 94/331 (28%), Gaps = 113/331 (34%)

Query: 700 PGPYHRGRGGRGGNEPPPPPPPFRGAR--------GGRSGGGPPNGRGGP---------- 741
           P PY     G G   P  P  P  GA            S   PP G G            
Sbjct: 349 PSPYDDLTYGEGEENPDQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEET 408

Query: 742 ----------------------GGGM--------VGGGGHRPHEGPGGGMGNSSGHRPHE 771
                                 G GM         G GG R  +G  G           E
Sbjct: 409 IRNLDENYYDPYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIE 468

Query: 772 GPGGGMGSGHRPHEGPGGSMGGGG--GHRPHEGPGG--GISGGSGHRPHEGP-------- 819
           GP G  G    P  GP G+MG  G  G     GP G  G+ G  G     G         
Sbjct: 469 GPPGPEGPAGLP--GPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRF 526

Query: 820 GGGMGAGG------------------GHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRP 861
           GGG  AG                         GP G MG +G   P   PG GG  G  P
Sbjct: 527 GGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKG-EP 585

Query: 862 HDVPGHRGHDHRGPP-------PHEHRGHDG----PGH-GGGGHRGHDGGHSHGGDMSNR 909
            DV        +GPP            G DG    PG  G  G RG DG     G+  +R
Sbjct: 586 GDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHR 645

Query: 910 PVCRHFMMKGNCRYENNCAFYHPGVNGPPLP 940
                                 PG +GPP P
Sbjct: 646 G--------------------DPGPSGPPGP 656



 Score = 31.2 bits (69), Expect = 4.7
 Identities = 35/137 (25%), Positives = 53/137 (38%), Gaps = 21/137 (15%)

Query: 330  PSTAKPSSPEPAPPSEAMDADRPGTPVPPVEVPELMDTASLEPGALDAKPVESPGDPNQL 389
            P  AK SS    P  EA     PG P PP EV        ++P  + A       D +QL
Sbjct: 1541 PKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEV--------IQPLPIQASRTRRNIDASQL 1592

Query: 390  TRKGRKRKSVTWPEEGKLREYFYFELDETERVNVNKIKDFGEAAKREILSDRHAFETAR- 448
               G     V + +   + E F          ++N +K   E  KR + + ++   T + 
Sbjct: 1593 LDDGNGENYVDYAD--GMEEIF---------GSLNSLKLEIEQMKRPLGTQQNPARTCKD 1641

Query: 449  -RLSHDNMEEKVPWVCP 464
             +L H +  +   WV P
Sbjct: 1642 LQLCHPDFPDGEYWVDP 1658


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
            sapiens]
          Length = 1424

 Score =  105 bits (261), Expect = 3e-22
 Identities = 131/386 (33%), Positives = 147/386 (38%), Gaps = 43/386 (11%)

Query: 538  EPGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPS 597
            EPG S G+  G  G    P L   MG  G    P  PG  G    E      G+P S  S
Sbjct: 1055 EPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPE------GAPGSPGS 1108

Query: 598  EELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFP--PGPGGPMPGPH 655
              L  +P           PHG LG   I     P G  GP G+  FP  PGP G + G  
Sbjct: 1109 PGLPGKPG----------PHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMG-IRGDQ 1157

Query: 656  GGPG--GPVGPR----LLGPPPPPRGGDPFWDGPGDPMRGGP-MRGGPGPGPGPYHRGRG 708
            G  G  GP G +    LL  PP PRG        GD  RG P   G PG        G  
Sbjct: 1158 GRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGD--RGAPGFPGLPGRKGAMGDAGPR 1215

Query: 709  GRGGNEPPPPPPPFRGA--RGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSG 766
            G  G E  P PP   GA   G     GPP  RG PG     G       G  G  G S G
Sbjct: 1216 GPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKG-SMG 1274

Query: 767  HRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPG-GGISGGSGHRPHEGPGGGMGA 825
            H   +GP G  G    P  G  G+ G  G   P   PG  G  G  G + + G  G +G 
Sbjct: 1275 HPGPKGPPGTAGDMGPP--GRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGP 1332

Query: 826  GGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRG-HDHRGPP-PHEHRGH 883
             G   P +GP G  G  G  +    PG  GP G      PG  G     GPP P  + G 
Sbjct: 1333 PGPIGP-KGPPGVRGDPGTLKIISLPGSPGPPG-----TPGEPGMQGEPGPPGPPGNLGP 1386

Query: 884  DGPGHGGGGHRGHDGGHSHGGDMSNR 909
             GP  G  G  G  G     G+  N+
Sbjct: 1387 CGP-RGKPGKDGKPGTPGPAGEKGNK 1411



 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 157/538 (29%), Positives = 187/538 (34%), Gaps = 130/538 (24%)

Query: 511 PYEPIPPKLIPLDEECSMDETPYVETLEPGGSGGSPDGAGGSKLPPVLA--------NLM 562
           PY P PP L  L     +   P  +     G  GSP   G + LP             L 
Sbjct: 480 PYIPGPPGLPGLPGLHGVKGIPGRQGA--AGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK 537

Query: 563 GSMGAGKGPQG----PGGGGINVQ---EILTSIMGSPNSH----PSEELLKQPDYSDKIK 611
           G  G    P+G    PG  G+  Q   + L  I G+P       P  EL    +  D+  
Sbjct: 538 GEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ-- 595

Query: 612 QMLVPHGLLG----PGPIANGFPPG-GPGGPKGMQHFPPGPGGPMP-------------- 652
               P G  G    PGP     PPG GP G  G+Q     PG P P              
Sbjct: 596 ---GPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652

Query: 653 ---GPHGGPGGPVGPRLLGPPPPP----RGGDPFWDGP-GDPMRGGPMRGGPGPGPGPYH 704
              GP G PG P  P   GPP  P    + GDP   GP G+P  G P  G PGP PGP  
Sbjct: 653 PVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEP--GIPGIGFPGP-PGP-- 707

Query: 705 RGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGG------GGHRPHEGPG 758
           +G  G  G +     P   G  G     G P  +G P   M GG       G R + G  
Sbjct: 708 KGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767

Query: 759 G-----------------GMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMG--------G 793
           G                 G+    G     GP G  G   R  EGP G+ G        G
Sbjct: 768 GEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKG 827

Query: 794 GGGHRPHEGPGG-------------GISGGSGHRPHEGPGGGMGAGG--------GHRPH 832
             G R   GP G             G +G  G   H+G  G +G  G        G    
Sbjct: 828 QQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGE 887

Query: 833 EGPGGSMGGSGGHRPHEGPGHGGPHGHR-PHDVPGHRGHDHRGPP----PHEHRGHDGPG 887
           +G  G MG  G   P   PG+ G  G R    +PG +G   RG P        +G+ GP 
Sbjct: 888 DGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKG--QRGTPGAKGEQGDKGNPGPS 945

Query: 888 H-----GGGGHRGHDGGHSHGGDMSNRPVCRHFMMKGNCRYENNCAFYHPGVNGPPLP 940
                 G  G  G  G   + G+  NR V     +KG            PG  GPP P
Sbjct: 946 EISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGL--------PGPAGPPGP 995



 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 129/414 (31%), Positives = 144/414 (34%), Gaps = 89/414 (21%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
            P G+ G+P   G   +P V     G+ GA KG QG  G                N  PSE
Sbjct: 905  PPGNPGTPGQRGSPGIPGVKGQ-RGTPGA-KGEQGDKG----------------NPGPSE 946

Query: 599  ELLKQPDYSDKIKQMLVPHGLLG----PGPIANGFPPGGPG--GPKGMQHFPPGPGGPMP 652
                    S  I     P GL G    PG   N   PG PG  G KG+    PGP GP P
Sbjct: 947  -------ISHVIGDKGEP-GLKGFAGNPGEKGNRGVPGMPGLKGLKGL----PGPAGP-P 993

Query: 653  GPHG---GPGGPVGPRLLGPPP-------------------PPRGGDPFWDG-------P 683
            GP G     G P  P L G P                    P R G P   G        
Sbjct: 994  GPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDK 1053

Query: 684  GDP-MRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG 742
            G+P    G   G PGP   P   G  G+ G    P PP   G  G     G P   G PG
Sbjct: 1054 GEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPG 1113

Query: 743  ----GGMVGGGGHRPHEGPGG--GMGNSSGHRPHEGPGGGMG-SGHRPHEGPGGSMGGGG 795
                 G +G  G +   GP G  G     G     GP G  G  G     GP G  G  G
Sbjct: 1114 KPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETG 1173

Query: 796  GHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGG 855
              R   GP G   G  G +   G  G  G         G  G+MG +G   P    G  G
Sbjct: 1174 LLRAPPGPRGN-PGAQGAKGDRGAPGFPGL-------PGRKGAMGDAGPRGPTGIEGFPG 1225

Query: 856  PHGHRPHDVPGHRGHDHRGPP-PHEHRGHDGPGHGGGGH----RGHDGGHSHGG 904
            P G     +PG  G  +RGPP      G  GP    G H    +G  G   H G
Sbjct: 1226 PPGLPGAIIPGQTG--NRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPG 1277



 Score = 77.8 bits (190), Expect = 4e-14
 Identities = 127/410 (30%), Positives = 148/410 (36%), Gaps = 95/410 (23%)

Query: 541 GSGGSPDGAGGSKLP-------PVLANLMGSMGAGKGPQGPGG--GGINVQEILTSIMGS 591
           GS GSP  AG +  P       P L    G  GA  GP G  G  G ++V   +    G 
Sbjct: 602 GSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA-PGPPGEAGPRGELSVSTPVPGPPGP 660

Query: 592 PN--SHPSEELLKQPDYSDKIKQMLVPHGLLGP----GPIANGFPPGGPGGPKGMQHFP- 644
           P    HP  +    P     + +   P GL GP    G    GFP  GP GPKG Q FP 
Sbjct: 661 PGPPGHPGPQ--GPPGIPGSLGKCGDP-GLPGPDGEPGIPGIGFP--GPPGPKGDQGFPG 715

Query: 645 ----------------------PG---------PGGP----MPGPHGGPG--GPVG-PRL 666
                                 PG         PGGP     PG  G  G  G +G P L
Sbjct: 716 TKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGL 775

Query: 667 LGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGAR 726
            G P  P  G+   DGP    RG P + GP    GP  R   G  G +  P     +G +
Sbjct: 776 PGLPGTP--GNEGLDGP----RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQ 829

Query: 727 GGRSGGGPPNGRGGPG------GGMVGGGGHRPHEGPGGGMGNSS--GHRPHEGPGGGMG 778
           G R   GP    G PG       G  G  G   H+G  G +G     G+    GP G  G
Sbjct: 830 GRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDG 889

Query: 779 ----SGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHE- 833
                G     GP G  G  G   P +    GI G  G R   G  G  G  G   P E 
Sbjct: 890 VIGMMGFPGAIGPPGPPGNPG--TPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEI 947

Query: 834 ----GPGGSMG-----GSGGHRPHEG-PGHGGPHGHR----PHDVPGHRG 869
               G  G  G     G+ G + + G PG  G  G +    P   PG RG
Sbjct: 948 SHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRG 997



 Score = 77.4 bits (189), Expect = 6e-14
 Identities = 121/412 (29%), Positives = 145/412 (35%), Gaps = 99/412 (24%)

Query: 539 PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGG----GGINVQEILTSIMGSPNS 594
           P GS G     G   LP              GPQGP G     G+   + +  I G P  
Sbjct: 56  PPGSPGQKGFTGPEGLP--------------GPQGPKGFPGLPGLTGSKGVRGISGLPGF 101

Query: 595 HPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGP 654
             S  L   P  +        P+GL+G           G  G KG Q FP      +PG 
Sbjct: 102 SGSPGLPGTPGNTG-------PYGLVGVP---------GCSGSKGEQGFPG-----LPGT 140

Query: 655 HGGPGGPVGPRLLGPP-PPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGN 713
            G PG P    L G    P +  D   D  GDP  G P   GP   PGP      G  G 
Sbjct: 141 LGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDP--GLPGAPGPQGLPGP-----PGFPGP 193

Query: 714 EPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGG-------------G 760
             PP PP F G  G     GP   +G  G  ++G  G R  +G  G             G
Sbjct: 194 VGPPGPPGFFGFPGAMGPRGP---KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTG 250

Query: 761 MGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMG-------GGGGHRPHEGPGG-----GIS 808
             N +  +  +G  G MG    P  GP G  G       G  G    +G  G     G  
Sbjct: 251 PDNRTDLKGEKGDKGAMGEPGPP--GPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFP 308

Query: 809 GGSGHRPHEGPGGGMGAGG--GHRPHEGPGGSMGGSGGHRPHE------GPGHGGPHGHR 860
           G  G + + G  G MG  G  G +   GP G  G +  +  ++       PG  GP G R
Sbjct: 309 GSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGAR 368

Query: 861 -------PHDVPGHRGHDHRGPPPHEHRGHDG-PG-HGGGGHRGHDGGHSHG 903
                  P  VPG  G    G      RG  G PG  G  G RG  G  + G
Sbjct: 369 GPQGPSGPPGVPGSPGSSRPG-----LRGAPGWPGLKGSKGERGRPGKDAMG 415



 Score = 77.4 bits (189), Expect = 6e-14
 Identities = 120/411 (29%), Positives = 138/411 (33%), Gaps = 109/411 (26%)

Query: 539 PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
           P G  G P G  GSK       L G++G    P  PG  G+  Q+      G+P      
Sbjct: 116 PYGLVGVP-GCSGSKGEQGFPGLPGTLGY---PGIPGAAGLKGQK------GAPAKEEDI 165

Query: 599 ELLKQPDYSDKIKQMLVPHGLLGP----GPIANGFPPG--------GPGGPKGMQHF--- 643
           EL  + D    +     P GL GP    GP+    PPG        GP GPKG       
Sbjct: 166 ELDAKGDPG--LPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVI 223

Query: 644 -------------PPGPGGPM----------------------------PGPHGGPGGPV 662
                        PPGP G +                            PGP G PG   
Sbjct: 224 GHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESY 283

Query: 663 GPRLLGPPPPPRGGDPFWDG-PGDP-------MRGGP----------MRGGPGP----GP 700
           G     P  P   G P  DG PG P        RG P           +G  GP    GP
Sbjct: 284 GSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGP 343

Query: 701 GPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPG-G 759
             Y+     +G    P PP P RGARG +   GPP   G PG    G  G      PG  
Sbjct: 344 TEYYDTYQEKGDEGTPGPPGP-RGARGPQGPSGPPGVPGSPGSSRPGLRG-----APGWP 397

Query: 760 GMGNSSGHRPHEG------PGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGG-----GIS 808
           G+  S G R   G      PG    +G     G  G  G  G     +GP G     G  
Sbjct: 398 GLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYL 457

Query: 809 GGSGHRPHEGPGGGMGAGGGHRPH-EGPGGSMGGSGGHRPHEGPGHGGPHG 858
           G  G    +GP G  G      P+  GP G  G  G H     PG  G  G
Sbjct: 458 GSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAG 508



 Score = 67.0 bits (162), Expect = 8e-11
 Identities = 91/285 (31%), Positives = 96/285 (33%), Gaps = 78/285 (27%)

Query: 539  PGGSGGSP--DGAGGSKLPPVLANLMGSMGA--GKGPQGPGGGGINVQEILTSIMGSPNS 594
            P G  G+P   GA G +  P    L G  GA    GP+GP           T I G P  
Sbjct: 1178 PPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGP-----------TGIEGFPG- 1225

Query: 595  HPSEELLKQPDYSDKIKQMLVPHGLLG---PGPIANGFPPGGPGGPKGMQHFPPGPGGPM 651
                                 P GL G   PG   N  PPG  G P       PGP GP 
Sbjct: 1226 ---------------------PPGLPGAIIPGQTGNRGPPGSRGSPGA-----PGPPGP- 1258

Query: 652  PGPH-----GGPGGPVGPRLLGPP-------PPPRGGDPFWDGPGDPMRGGPMRGGPGPG 699
            PG H     G  G    P   GPP       PP R G      PG P   GP RG PG  
Sbjct: 1259 PGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLG-----APGTPGLPGP-RGDPGFQ 1312

Query: 700  PGPYHRGRGGR----GGNEPPPP-----PPPFRGARGGRSGGGPPNGRGGPGGGMVGGGG 750
              P  +G  G     G   PP P     PP  RG  G       P   G PG    G  G
Sbjct: 1313 GFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPG--TPGEPG 1370

Query: 751  HRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGG 795
             +   GP G  GN     P   PG     G     GP G  G  G
Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKPG---KDGKPGTPGPAGEKGNKG 1412



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 93/307 (30%), Positives = 107/307 (34%), Gaps = 47/307 (15%)

Query: 633 GPGGPKGMQHFPPGPGGP----------MPGPHGGPGGPVGPRLLGPPPPPRG--GDPFW 680
           G  G KG + FP  PG P          +PGP G  G P  P L G     RG  G P +
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTG-SKGVRGISGLPGF 101

Query: 681 DG----PGDPMRGGP--MRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGR----- 729
            G    PG P   GP  + G PG       +G  G  G    P  P   G +G +     
Sbjct: 102 SGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAK 161

Query: 730 ------SGGGPPNGRGGPG-GGMVGGGGHRPHEGPGG--GMGNSSGHRPHEGPGGGMGSG 780
                    G P   G PG  G+ G  G     GP G  G     G     GP G MG  
Sbjct: 162 EEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGER 221

Query: 781 HRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMG 840
              H+G  G  G  G   P       ++G       +G  G  GA G   P  GP G  G
Sbjct: 222 VIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGP-PGPSGLPG 280

Query: 841 GSGGHRPHEGPGHGGPHGHRPHD-VPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDGG 899
            S G      PG  G  G    D VPG  G +          G  G   G  G  G DG 
Sbjct: 281 ESYGSE-KGAPGDPGLQGKPGKDGVPGFPGSE----------GVKG-NRGFPGLMGEDGI 328

Query: 900 HSHGGDM 906
               GD+
Sbjct: 329 KGQKGDI 335



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 74/224 (33%), Positives = 87/224 (38%), Gaps = 41/224 (18%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNS--HP 596
            PG  G    G  G++ PP      GS G+   P  PG  G +V      I G   S  HP
Sbjct: 1227 PGLPGAIIPGQTGNRGPP------GSRGSPGAPGPPGPPGSHV----IGIKGDKGSMGHP 1276

Query: 597  SEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGP-MPGPH 655
                   P         + P G LG  P   G P  GP G  G Q FP   G    PG  
Sbjct: 1277 G------PKGPPGTAGDMGPPGRLG-APGTPGLP--GPRGDPGFQGFPGVKGEKGNPGFL 1327

Query: 656  G--GPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGN 713
            G  GP GP+GP+     PP   GDP        ++   + G PGP   P   G  G  G 
Sbjct: 1328 GSIGPPGPIGPK----GPPGVRGDP------GTLKIISLPGSPGPPGTP---GEPGMQGE 1374

Query: 714  EPPPPPPPFRGARGGRSGGGPPNGRGGPG-GGMVGGGGHRPHEG 756
              PP PP   G  G R   G P   G PG  G  G  G++  +G
Sbjct: 1375 PGPPGPPGNLGPCGPR---GKPGKDGKPGTPGPAGEKGNKGSKG 1415


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
            sapiens]
          Length = 1494

 Score =  105 bits (261), Expect = 3e-22
 Identities = 131/386 (33%), Positives = 147/386 (38%), Gaps = 43/386 (11%)

Query: 538  EPGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPS 597
            EPG S G+  G  G    P L   MG  G    P  PG  G    E      G+P S  S
Sbjct: 1055 EPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPE------GAPGSPGS 1108

Query: 598  EELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFP--PGPGGPMPGPH 655
              L  +P           PHG LG   I     P G  GP G+  FP  PGP G + G  
Sbjct: 1109 PGLPGKPG----------PHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMG-IRGDQ 1157

Query: 656  GGPG--GPVGPR----LLGPPPPPRGGDPFWDGPGDPMRGGP-MRGGPGPGPGPYHRGRG 708
            G  G  GP G +    LL  PP PRG        GD  RG P   G PG        G  
Sbjct: 1158 GRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGD--RGAPGFPGLPGRKGAMGDAGPR 1215

Query: 709  GRGGNEPPPPPPPFRGA--RGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSG 766
            G  G E  P PP   GA   G     GPP  RG PG     G       G  G  G S G
Sbjct: 1216 GPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKG-SMG 1274

Query: 767  HRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPG-GGISGGSGHRPHEGPGGGMGA 825
            H   +GP G  G    P  G  G+ G  G   P   PG  G  G  G + + G  G +G 
Sbjct: 1275 HPGPKGPPGTAGDMGPP--GRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGP 1332

Query: 826  GGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRG-HDHRGPP-PHEHRGH 883
             G   P +GP G  G  G  +    PG  GP G      PG  G     GPP P  + G 
Sbjct: 1333 PGPIGP-KGPPGVRGDPGTLKIISLPGSPGPPG-----TPGEPGMQGEPGPPGPPGNLGP 1386

Query: 884  DGPGHGGGGHRGHDGGHSHGGDMSNR 909
             GP  G  G  G  G     G+  N+
Sbjct: 1387 CGP-RGKPGKDGKPGTPGPAGEKGNK 1411



 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 157/538 (29%), Positives = 187/538 (34%), Gaps = 130/538 (24%)

Query: 511 PYEPIPPKLIPLDEECSMDETPYVETLEPGGSGGSPDGAGGSKLPPVLA--------NLM 562
           PY P PP L  L     +   P  +     G  GSP   G + LP             L 
Sbjct: 480 PYIPGPPGLPGLPGLHGVKGIPGRQGA--AGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK 537

Query: 563 GSMGAGKGPQG----PGGGGINVQ---EILTSIMGSPNSH----PSEELLKQPDYSDKIK 611
           G  G    P+G    PG  G+  Q   + L  I G+P       P  EL    +  D+  
Sbjct: 538 GEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ-- 595

Query: 612 QMLVPHGLLG----PGPIANGFPPG-GPGGPKGMQHFPPGPGGPMP-------------- 652
               P G  G    PGP     PPG GP G  G+Q     PG P P              
Sbjct: 596 ---GPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652

Query: 653 ---GPHGGPGGPVGPRLLGPPPPP----RGGDPFWDGP-GDPMRGGPMRGGPGPGPGPYH 704
              GP G PG P  P   GPP  P    + GDP   GP G+P  G P  G PGP PGP  
Sbjct: 653 PVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEP--GIPGIGFPGP-PGP-- 707

Query: 705 RGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGG------GGHRPHEGPG 758
           +G  G  G +     P   G  G     G P  +G P   M GG       G R + G  
Sbjct: 708 KGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767

Query: 759 G-----------------GMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMG--------G 793
           G                 G+    G     GP G  G   R  EGP G+ G        G
Sbjct: 768 GEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKG 827

Query: 794 GGGHRPHEGPGG-------------GISGGSGHRPHEGPGGGMGAGG--------GHRPH 832
             G R   GP G             G +G  G   H+G  G +G  G        G    
Sbjct: 828 QQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGE 887

Query: 833 EGPGGSMGGSGGHRPHEGPGHGGPHGHR-PHDVPGHRGHDHRGPP----PHEHRGHDGPG 887
           +G  G MG  G   P   PG+ G  G R    +PG +G   RG P        +G+ GP 
Sbjct: 888 DGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKG--QRGTPGAKGEQGDKGNPGPS 945

Query: 888 H-----GGGGHRGHDGGHSHGGDMSNRPVCRHFMMKGNCRYENNCAFYHPGVNGPPLP 940
                 G  G  G  G   + G+  NR V     +KG            PG  GPP P
Sbjct: 946 EISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGL--------PGPAGPPGP 995



 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 129/414 (31%), Positives = 144/414 (34%), Gaps = 89/414 (21%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
            P G+ G+P   G   +P V     G+ GA KG QG  G                N  PSE
Sbjct: 905  PPGNPGTPGQRGSPGIPGVKGQ-RGTPGA-KGEQGDKG----------------NPGPSE 946

Query: 599  ELLKQPDYSDKIKQMLVPHGLLG----PGPIANGFPPGGPG--GPKGMQHFPPGPGGPMP 652
                    S  I     P GL G    PG   N   PG PG  G KG+    PGP GP P
Sbjct: 947  -------ISHVIGDKGEP-GLKGFAGNPGEKGNRGVPGMPGLKGLKGL----PGPAGP-P 993

Query: 653  GPHG---GPGGPVGPRLLGPPP-------------------PPRGGDPFWDG-------P 683
            GP G     G P  P L G P                    P R G P   G        
Sbjct: 994  GPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDK 1053

Query: 684  GDP-MRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG 742
            G+P    G   G PGP   P   G  G+ G    P PP   G  G     G P   G PG
Sbjct: 1054 GEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPG 1113

Query: 743  ----GGMVGGGGHRPHEGPGG--GMGNSSGHRPHEGPGGGMG-SGHRPHEGPGGSMGGGG 795
                 G +G  G +   GP G  G     G     GP G  G  G     GP G  G  G
Sbjct: 1114 KPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETG 1173

Query: 796  GHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGG 855
              R   GP G   G  G +   G  G  G         G  G+MG +G   P    G  G
Sbjct: 1174 LLRAPPGPRGN-PGAQGAKGDRGAPGFPGL-------PGRKGAMGDAGPRGPTGIEGFPG 1225

Query: 856  PHGHRPHDVPGHRGHDHRGPP-PHEHRGHDGPGHGGGGH----RGHDGGHSHGG 904
            P G     +PG  G  +RGPP      G  GP    G H    +G  G   H G
Sbjct: 1226 PPGLPGAIIPGQTG--NRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPG 1277



 Score = 77.8 bits (190), Expect = 4e-14
 Identities = 127/410 (30%), Positives = 148/410 (36%), Gaps = 95/410 (23%)

Query: 541 GSGGSPDGAGGSKLP-------PVLANLMGSMGAGKGPQGPGG--GGINVQEILTSIMGS 591
           GS GSP  AG +  P       P L    G  GA  GP G  G  G ++V   +    G 
Sbjct: 602 GSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA-PGPPGEAGPRGELSVSTPVPGPPGP 660

Query: 592 PN--SHPSEELLKQPDYSDKIKQMLVPHGLLGP----GPIANGFPPGGPGGPKGMQHFP- 644
           P    HP  +    P     + +   P GL GP    G    GFP  GP GPKG Q FP 
Sbjct: 661 PGPPGHPGPQ--GPPGIPGSLGKCGDP-GLPGPDGEPGIPGIGFP--GPPGPKGDQGFPG 715

Query: 645 ----------------------PG---------PGGP----MPGPHGGPG--GPVG-PRL 666
                                 PG         PGGP     PG  G  G  G +G P L
Sbjct: 716 TKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGL 775

Query: 667 LGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGAR 726
            G P  P  G+   DGP    RG P + GP    GP  R   G  G +  P     +G +
Sbjct: 776 PGLPGTP--GNEGLDGP----RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQ 829

Query: 727 GGRSGGGPPNGRGGPG------GGMVGGGGHRPHEGPGGGMGNSS--GHRPHEGPGGGMG 778
           G R   GP    G PG       G  G  G   H+G  G +G     G+    GP G  G
Sbjct: 830 GRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDG 889

Query: 779 ----SGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHE- 833
                G     GP G  G  G   P +    GI G  G R   G  G  G  G   P E 
Sbjct: 890 VIGMMGFPGAIGPPGPPGNPG--TPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEI 947

Query: 834 ----GPGGSMG-----GSGGHRPHEG-PGHGGPHGHR----PHDVPGHRG 869
               G  G  G     G+ G + + G PG  G  G +    P   PG RG
Sbjct: 948 SHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRG 997



 Score = 77.4 bits (189), Expect = 6e-14
 Identities = 121/412 (29%), Positives = 145/412 (35%), Gaps = 99/412 (24%)

Query: 539 PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGG----GGINVQEILTSIMGSPNS 594
           P GS G     G   LP              GPQGP G     G+   + +  I G P  
Sbjct: 56  PPGSPGQKGFTGPEGLP--------------GPQGPKGFPGLPGLTGSKGVRGISGLPGF 101

Query: 595 HPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGP 654
             S  L   P  +        P+GL+G           G  G KG Q FP      +PG 
Sbjct: 102 SGSPGLPGTPGNTG-------PYGLVGVP---------GCSGSKGEQGFPG-----LPGT 140

Query: 655 HGGPGGPVGPRLLGPP-PPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGN 713
            G PG P    L G    P +  D   D  GDP  G P   GP   PGP      G  G 
Sbjct: 141 LGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDP--GLPGAPGPQGLPGP-----PGFPGP 193

Query: 714 EPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGG-------------G 760
             PP PP F G  G     GP   +G  G  ++G  G R  +G  G             G
Sbjct: 194 VGPPGPPGFFGFPGAMGPRGP---KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTG 250

Query: 761 MGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMG-------GGGGHRPHEGPGG-----GIS 808
             N +  +  +G  G MG    P  GP G  G       G  G    +G  G     G  
Sbjct: 251 PDNRTDLKGEKGDKGAMGEPGPP--GPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFP 308

Query: 809 GGSGHRPHEGPGGGMGAGG--GHRPHEGPGGSMGGSGGHRPHE------GPGHGGPHGHR 860
           G  G + + G  G MG  G  G +   GP G  G +  +  ++       PG  GP G R
Sbjct: 309 GSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGAR 368

Query: 861 -------PHDVPGHRGHDHRGPPPHEHRGHDG-PG-HGGGGHRGHDGGHSHG 903
                  P  VPG  G    G      RG  G PG  G  G RG  G  + G
Sbjct: 369 GPQGPSGPPGVPGSPGSSRPG-----LRGAPGWPGLKGSKGERGRPGKDAMG 415



 Score = 77.4 bits (189), Expect = 6e-14
 Identities = 120/411 (29%), Positives = 138/411 (33%), Gaps = 109/411 (26%)

Query: 539 PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
           P G  G P G  GSK       L G++G    P  PG  G+  Q+      G+P      
Sbjct: 116 PYGLVGVP-GCSGSKGEQGFPGLPGTLGY---PGIPGAAGLKGQK------GAPAKEEDI 165

Query: 599 ELLKQPDYSDKIKQMLVPHGLLGP----GPIANGFPPG--------GPGGPKGMQHF--- 643
           EL  + D    +     P GL GP    GP+    PPG        GP GPKG       
Sbjct: 166 ELDAKGDPG--LPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVI 223

Query: 644 -------------PPGPGGPM----------------------------PGPHGGPGGPV 662
                        PPGP G +                            PGP G PG   
Sbjct: 224 GHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESY 283

Query: 663 GPRLLGPPPPPRGGDPFWDG-PGDP-------MRGGP----------MRGGPGP----GP 700
           G     P  P   G P  DG PG P        RG P           +G  GP    GP
Sbjct: 284 GSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGP 343

Query: 701 GPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPG-G 759
             Y+     +G    P PP P RGARG +   GPP   G PG    G  G      PG  
Sbjct: 344 TEYYDTYQEKGDEGTPGPPGP-RGARGPQGPSGPPGVPGSPGSSRPGLRG-----APGWP 397

Query: 760 GMGNSSGHRPHEG------PGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGG-----GIS 808
           G+  S G R   G      PG    +G     G  G  G  G     +GP G     G  
Sbjct: 398 GLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYL 457

Query: 809 GGSGHRPHEGPGGGMGAGGGHRPH-EGPGGSMGGSGGHRPHEGPGHGGPHG 858
           G  G    +GP G  G      P+  GP G  G  G H     PG  G  G
Sbjct: 458 GSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAG 508



 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 99/310 (31%), Positives = 106/310 (34%), Gaps = 81/310 (26%)

Query: 539  PGGSGGSP--DGAGGSKLPPVLANLMGSMGA--GKGPQGPGGGGINVQEILTSIMGSPNS 594
            P G  G+P   GA G +  P    L G  GA    GP+GP           T I G P  
Sbjct: 1178 PPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGP-----------TGIEGFPG- 1225

Query: 595  HPSEELLKQPDYSDKIKQMLVPHGLLG---PGPIANGFPPGGPGGPKGMQHFPPGPGGPM 651
                                 P GL G   PG   N  PPG  G P       PGP GP 
Sbjct: 1226 ---------------------PPGLPGAIIPGQTGNRGPPGSRGSPGA-----PGPPGP- 1258

Query: 652  PGPH-----GGPGGPVGPRLLGPP-------PPPRGGDPFWDGPGDPMRGGPMRGGPGPG 699
            PG H     G  G    P   GPP       PP R G      PG P   GP RG PG  
Sbjct: 1259 PGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLG-----APGTPGLPGP-RGDPGFQ 1312

Query: 700  PGPYHRGRGGR----GGNEPPPP-----PPPFRGARGGRSGGGPPNGRGGPGGGMVGGGG 750
              P  +G  G     G   PP P     PP  RG  G       P   G PG    G  G
Sbjct: 1313 GFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPG--TPGEPG 1370

Query: 751  HRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGG--GIS 808
             +   GP G  GN     P   PG     G     GP G  G  G  +   GP G  G+ 
Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKPG---KDGKPGTPGPAGEKGNKGS-KGEPGPAGSDGLP 1426

Query: 809  GGSGHRPHEG 818
            G  G R   G
Sbjct: 1427 GLKGKRGDSG 1436



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 93/307 (30%), Positives = 107/307 (34%), Gaps = 47/307 (15%)

Query: 633 GPGGPKGMQHFPPGPGGP----------MPGPHGGPGGPVGPRLLGPPPPPRG--GDPFW 680
           G  G KG + FP  PG P          +PGP G  G P  P L G     RG  G P +
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTG-SKGVRGISGLPGF 101

Query: 681 DG----PGDPMRGGP--MRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGR----- 729
            G    PG P   GP  + G PG       +G  G  G    P  P   G +G +     
Sbjct: 102 SGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAK 161

Query: 730 ------SGGGPPNGRGGPG-GGMVGGGGHRPHEGPGG--GMGNSSGHRPHEGPGGGMGSG 780
                    G P   G PG  G+ G  G     GP G  G     G     GP G MG  
Sbjct: 162 EEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGER 221

Query: 781 HRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMG 840
              H+G  G  G  G   P       ++G       +G  G  GA G   P  GP G  G
Sbjct: 222 VIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGP-PGPSGLPG 280

Query: 841 GSGGHRPHEGPGHGGPHGHRPHD-VPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDGG 899
            S G      PG  G  G    D VPG  G +          G  G   G  G  G DG 
Sbjct: 281 ESYGSE-KGAPGDPGLQGKPGKDGVPGFPGSE----------GVKG-NRGFPGLMGEDGI 328

Query: 900 HSHGGDM 906
               GD+
Sbjct: 329 KGQKGDI 335



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 73/218 (33%), Positives = 80/218 (36%), Gaps = 43/218 (19%)

Query: 539  PGGSGGSPDGAGGSKLPPV-----LANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPN 593
            P GS GSP GA G   PP      +    GSMG   GP+GP G            MG P 
Sbjct: 1243 PPGSRGSP-GAPGPPGPPGSHVIGIKGDKGSMGH-PGPKGPPG--------TAGDMGPPG 1292

Query: 594  --SHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGP- 650
                P    L  P      +      G  G         P GP GPKG    PPG  G  
Sbjct: 1293 RLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKG----PPGVRGDP 1348

Query: 651  -------MPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPG----PG 699
                   +PG  G PG P  P + G P PP  G P   GP  P      RG PG    PG
Sbjct: 1349 GTLKIISLPGSPGPPGTPGEPGMQGEPGPP--GPPGNLGPCGP------RGKPGKDGKPG 1400

Query: 700  -PGPY-HRGRGGRGGNEPPPPPPPFRGARGGRSGGGPP 735
             PGP   +G  G  G   P       G +G R   G P
Sbjct: 1401 TPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1637

 Score =  105 bits (261), Expect = 3e-22
 Identities = 131/386 (33%), Positives = 147/386 (38%), Gaps = 43/386 (11%)

Query: 538  EPGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPS 597
            EPG S G+  G  G    P L   MG  G    P  PG  G    E      G+P S  S
Sbjct: 1055 EPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPE------GAPGSPGS 1108

Query: 598  EELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFP--PGPGGPMPGPH 655
              L  +P           PHG LG   I     P G  GP G+  FP  PGP G + G  
Sbjct: 1109 PGLPGKPG----------PHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMG-IRGDQ 1157

Query: 656  GGPG--GPVGPR----LLGPPPPPRGGDPFWDGPGDPMRGGP-MRGGPGPGPGPYHRGRG 708
            G  G  GP G +    LL  PP PRG        GD  RG P   G PG        G  
Sbjct: 1158 GRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGD--RGAPGFPGLPGRKGAMGDAGPR 1215

Query: 709  GRGGNEPPPPPPPFRGA--RGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSG 766
            G  G E  P PP   GA   G     GPP  RG PG     G       G  G  G S G
Sbjct: 1216 GPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKG-SMG 1274

Query: 767  HRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPG-GGISGGSGHRPHEGPGGGMGA 825
            H   +GP G  G    P  G  G+ G  G   P   PG  G  G  G + + G  G +G 
Sbjct: 1275 HPGPKGPPGTAGDMGPP--GRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGP 1332

Query: 826  GGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRG-HDHRGPP-PHEHRGH 883
             G   P +GP G  G  G  +    PG  GP G      PG  G     GPP P  + G 
Sbjct: 1333 PGPIGP-KGPPGVRGDPGTLKIISLPGSPGPPG-----TPGEPGMQGEPGPPGPPGNLGP 1386

Query: 884  DGPGHGGGGHRGHDGGHSHGGDMSNR 909
             GP  G  G  G  G     G+  N+
Sbjct: 1387 CGP-RGKPGKDGKPGTPGPAGEKGNK 1411



 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 157/538 (29%), Positives = 187/538 (34%), Gaps = 130/538 (24%)

Query: 511 PYEPIPPKLIPLDEECSMDETPYVETLEPGGSGGSPDGAGGSKLPPVLA--------NLM 562
           PY P PP L  L     +   P  +     G  GSP   G + LP             L 
Sbjct: 480 PYIPGPPGLPGLPGLHGVKGIPGRQGA--AGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK 537

Query: 563 GSMGAGKGPQG----PGGGGINVQ---EILTSIMGSPNSH----PSEELLKQPDYSDKIK 611
           G  G    P+G    PG  G+  Q   + L  I G+P       P  EL    +  D+  
Sbjct: 538 GEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ-- 595

Query: 612 QMLVPHGLLG----PGPIANGFPPG-GPGGPKGMQHFPPGPGGPMP-------------- 652
               P G  G    PGP     PPG GP G  G+Q     PG P P              
Sbjct: 596 ---GPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652

Query: 653 ---GPHGGPGGPVGPRLLGPPPPP----RGGDPFWDGP-GDPMRGGPMRGGPGPGPGPYH 704
              GP G PG P  P   GPP  P    + GDP   GP G+P  G P  G PGP PGP  
Sbjct: 653 PVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEP--GIPGIGFPGP-PGP-- 707

Query: 705 RGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGG------GGHRPHEGPG 758
           +G  G  G +     P   G  G     G P  +G P   M GG       G R + G  
Sbjct: 708 KGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767

Query: 759 G-----------------GMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMG--------G 793
           G                 G+    G     GP G  G   R  EGP G+ G        G
Sbjct: 768 GEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKG 827

Query: 794 GGGHRPHEGPGG-------------GISGGSGHRPHEGPGGGMGAGG--------GHRPH 832
             G R   GP G             G +G  G   H+G  G +G  G        G    
Sbjct: 828 QQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGE 887

Query: 833 EGPGGSMGGSGGHRPHEGPGHGGPHGHR-PHDVPGHRGHDHRGPP----PHEHRGHDGPG 887
           +G  G MG  G   P   PG+ G  G R    +PG +G   RG P        +G+ GP 
Sbjct: 888 DGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKG--QRGTPGAKGEQGDKGNPGPS 945

Query: 888 H-----GGGGHRGHDGGHSHGGDMSNRPVCRHFMMKGNCRYENNCAFYHPGVNGPPLP 940
                 G  G  G  G   + G+  NR V     +KG            PG  GPP P
Sbjct: 946 EISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGL--------PGPAGPPGP 995



 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 129/414 (31%), Positives = 144/414 (34%), Gaps = 89/414 (21%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
            P G+ G+P   G   +P V     G+ GA KG QG  G                N  PSE
Sbjct: 905  PPGNPGTPGQRGSPGIPGVKGQ-RGTPGA-KGEQGDKG----------------NPGPSE 946

Query: 599  ELLKQPDYSDKIKQMLVPHGLLG----PGPIANGFPPGGPG--GPKGMQHFPPGPGGPMP 652
                    S  I     P GL G    PG   N   PG PG  G KG+    PGP GP P
Sbjct: 947  -------ISHVIGDKGEP-GLKGFAGNPGEKGNRGVPGMPGLKGLKGL----PGPAGP-P 993

Query: 653  GPHG---GPGGPVGPRLLGPPP-------------------PPRGGDPFWDG-------P 683
            GP G     G P  P L G P                    P R G P   G        
Sbjct: 994  GPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDK 1053

Query: 684  GDP-MRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG 742
            G+P    G   G PGP   P   G  G+ G    P PP   G  G     G P   G PG
Sbjct: 1054 GEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPG 1113

Query: 743  ----GGMVGGGGHRPHEGPGG--GMGNSSGHRPHEGPGGGMG-SGHRPHEGPGGSMGGGG 795
                 G +G  G +   GP G  G     G     GP G  G  G     GP G  G  G
Sbjct: 1114 KPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETG 1173

Query: 796  GHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGG 855
              R   GP G   G  G +   G  G  G         G  G+MG +G   P    G  G
Sbjct: 1174 LLRAPPGPRGN-PGAQGAKGDRGAPGFPGL-------PGRKGAMGDAGPRGPTGIEGFPG 1225

Query: 856  PHGHRPHDVPGHRGHDHRGPP-PHEHRGHDGPGHGGGGH----RGHDGGHSHGG 904
            P G     +PG  G  +RGPP      G  GP    G H    +G  G   H G
Sbjct: 1226 PPGLPGAIIPGQTG--NRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPG 1277



 Score = 77.8 bits (190), Expect = 4e-14
 Identities = 127/410 (30%), Positives = 148/410 (36%), Gaps = 95/410 (23%)

Query: 541 GSGGSPDGAGGSKLP-------PVLANLMGSMGAGKGPQGPGG--GGINVQEILTSIMGS 591
           GS GSP  AG +  P       P L    G  GA  GP G  G  G ++V   +    G 
Sbjct: 602 GSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA-PGPPGEAGPRGELSVSTPVPGPPGP 660

Query: 592 PN--SHPSEELLKQPDYSDKIKQMLVPHGLLGP----GPIANGFPPGGPGGPKGMQHFP- 644
           P    HP  +    P     + +   P GL GP    G    GFP  GP GPKG Q FP 
Sbjct: 661 PGPPGHPGPQ--GPPGIPGSLGKCGDP-GLPGPDGEPGIPGIGFP--GPPGPKGDQGFPG 715

Query: 645 ----------------------PG---------PGGP----MPGPHGGPG--GPVG-PRL 666
                                 PG         PGGP     PG  G  G  G +G P L
Sbjct: 716 TKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGL 775

Query: 667 LGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGAR 726
            G P  P  G+   DGP    RG P + GP    GP  R   G  G +  P     +G +
Sbjct: 776 PGLPGTP--GNEGLDGP----RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQ 829

Query: 727 GGRSGGGPPNGRGGPG------GGMVGGGGHRPHEGPGGGMGNSS--GHRPHEGPGGGMG 778
           G R   GP    G PG       G  G  G   H+G  G +G     G+    GP G  G
Sbjct: 830 GRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDG 889

Query: 779 ----SGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHE- 833
                G     GP G  G  G   P +    GI G  G R   G  G  G  G   P E 
Sbjct: 890 VIGMMGFPGAIGPPGPPGNPG--TPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEI 947

Query: 834 ----GPGGSMG-----GSGGHRPHEG-PGHGGPHGHR----PHDVPGHRG 869
               G  G  G     G+ G + + G PG  G  G +    P   PG RG
Sbjct: 948 SHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRG 997



 Score = 77.4 bits (189), Expect = 6e-14
 Identities = 121/412 (29%), Positives = 145/412 (35%), Gaps = 99/412 (24%)

Query: 539 PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGG----GGINVQEILTSIMGSPNS 594
           P GS G     G   LP              GPQGP G     G+   + +  I G P  
Sbjct: 56  PPGSPGQKGFTGPEGLP--------------GPQGPKGFPGLPGLTGSKGVRGISGLPGF 101

Query: 595 HPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGP 654
             S  L   P  +        P+GL+G           G  G KG Q FP      +PG 
Sbjct: 102 SGSPGLPGTPGNTG-------PYGLVGVP---------GCSGSKGEQGFPG-----LPGT 140

Query: 655 HGGPGGPVGPRLLGPP-PPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGN 713
            G PG P    L G    P +  D   D  GDP  G P   GP   PGP      G  G 
Sbjct: 141 LGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDP--GLPGAPGPQGLPGP-----PGFPGP 193

Query: 714 EPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGG-------------G 760
             PP PP F G  G     GP   +G  G  ++G  G R  +G  G             G
Sbjct: 194 VGPPGPPGFFGFPGAMGPRGP---KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTG 250

Query: 761 MGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMG-------GGGGHRPHEGPGG-----GIS 808
             N +  +  +G  G MG    P  GP G  G       G  G    +G  G     G  
Sbjct: 251 PDNRTDLKGEKGDKGAMGEPGPP--GPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFP 308

Query: 809 GGSGHRPHEGPGGGMGAGG--GHRPHEGPGGSMGGSGGHRPHE------GPGHGGPHGHR 860
           G  G + + G  G MG  G  G +   GP G  G +  +  ++       PG  GP G R
Sbjct: 309 GSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGAR 368

Query: 861 -------PHDVPGHRGHDHRGPPPHEHRGHDG-PG-HGGGGHRGHDGGHSHG 903
                  P  VPG  G    G      RG  G PG  G  G RG  G  + G
Sbjct: 369 GPQGPSGPPGVPGSPGSSRPG-----LRGAPGWPGLKGSKGERGRPGKDAMG 415



 Score = 77.4 bits (189), Expect = 6e-14
 Identities = 120/411 (29%), Positives = 138/411 (33%), Gaps = 109/411 (26%)

Query: 539 PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
           P G  G P G  GSK       L G++G    P  PG  G+  Q+      G+P      
Sbjct: 116 PYGLVGVP-GCSGSKGEQGFPGLPGTLGY---PGIPGAAGLKGQK------GAPAKEEDI 165

Query: 599 ELLKQPDYSDKIKQMLVPHGLLGP----GPIANGFPPG--------GPGGPKGMQHF--- 643
           EL  + D    +     P GL GP    GP+    PPG        GP GPKG       
Sbjct: 166 ELDAKGDPG--LPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVI 223

Query: 644 -------------PPGPGGPM----------------------------PGPHGGPGGPV 662
                        PPGP G +                            PGP G PG   
Sbjct: 224 GHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESY 283

Query: 663 GPRLLGPPPPPRGGDPFWDG-PGDP-------MRGGP----------MRGGPGP----GP 700
           G     P  P   G P  DG PG P        RG P           +G  GP    GP
Sbjct: 284 GSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGP 343

Query: 701 GPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPG-G 759
             Y+     +G    P PP P RGARG +   GPP   G PG    G  G      PG  
Sbjct: 344 TEYYDTYQEKGDEGTPGPPGP-RGARGPQGPSGPPGVPGSPGSSRPGLRG-----APGWP 397

Query: 760 GMGNSSGHRPHEG------PGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGG-----GIS 808
           G+  S G R   G      PG    +G     G  G  G  G     +GP G     G  
Sbjct: 398 GLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYL 457

Query: 809 GGSGHRPHEGPGGGMGAGGGHRPH-EGPGGSMGGSGGHRPHEGPGHGGPHG 858
           G  G    +GP G  G      P+  GP G  G  G H     PG  G  G
Sbjct: 458 GSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAG 508



 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 99/310 (31%), Positives = 106/310 (34%), Gaps = 81/310 (26%)

Query: 539  PGGSGGSP--DGAGGSKLPPVLANLMGSMGA--GKGPQGPGGGGINVQEILTSIMGSPNS 594
            P G  G+P   GA G +  P    L G  GA    GP+GP           T I G P  
Sbjct: 1178 PPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGP-----------TGIEGFPG- 1225

Query: 595  HPSEELLKQPDYSDKIKQMLVPHGLLG---PGPIANGFPPGGPGGPKGMQHFPPGPGGPM 651
                                 P GL G   PG   N  PPG  G P       PGP GP 
Sbjct: 1226 ---------------------PPGLPGAIIPGQTGNRGPPGSRGSPGA-----PGPPGP- 1258

Query: 652  PGPH-----GGPGGPVGPRLLGPP-------PPPRGGDPFWDGPGDPMRGGPMRGGPGPG 699
            PG H     G  G    P   GPP       PP R G      PG P   GP RG PG  
Sbjct: 1259 PGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLG-----APGTPGLPGP-RGDPGFQ 1312

Query: 700  PGPYHRGRGGR----GGNEPPPP-----PPPFRGARGGRSGGGPPNGRGGPGGGMVGGGG 750
              P  +G  G     G   PP P     PP  RG  G       P   G PG    G  G
Sbjct: 1313 GFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPG--TPGEPG 1370

Query: 751  HRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGG--GIS 808
             +   GP G  GN     P   PG     G     GP G  G  G  +   GP G  G+ 
Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKPG---KDGKPGTPGPAGEKGNKGS-KGEPGPAGSDGLP 1426

Query: 809  GGSGHRPHEG 818
            G  G R   G
Sbjct: 1427 GLKGKRGDSG 1436



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 93/307 (30%), Positives = 107/307 (34%), Gaps = 47/307 (15%)

Query: 633 GPGGPKGMQHFPPGPGGP----------MPGPHGGPGGPVGPRLLGPPPPPRG--GDPFW 680
           G  G KG + FP  PG P          +PGP G  G P  P L G     RG  G P +
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTG-SKGVRGISGLPGF 101

Query: 681 DG----PGDPMRGGP--MRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGR----- 729
            G    PG P   GP  + G PG       +G  G  G    P  P   G +G +     
Sbjct: 102 SGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAK 161

Query: 730 ------SGGGPPNGRGGPG-GGMVGGGGHRPHEGPGG--GMGNSSGHRPHEGPGGGMGSG 780
                    G P   G PG  G+ G  G     GP G  G     G     GP G MG  
Sbjct: 162 EEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGER 221

Query: 781 HRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMG 840
              H+G  G  G  G   P       ++G       +G  G  GA G   P  GP G  G
Sbjct: 222 VIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGP-PGPSGLPG 280

Query: 841 GSGGHRPHEGPGHGGPHGHRPHD-VPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDGG 899
            S G      PG  G  G    D VPG  G +          G  G   G  G  G DG 
Sbjct: 281 ESYGSE-KGAPGDPGLQGKPGKDGVPGFPGSE----------GVKG-NRGFPGLMGEDGI 328

Query: 900 HSHGGDM 906
               GD+
Sbjct: 329 KGQKGDI 335



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 73/218 (33%), Positives = 80/218 (36%), Gaps = 43/218 (19%)

Query: 539  PGGSGGSPDGAGGSKLPPV-----LANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPN 593
            P GS GSP GA G   PP      +    GSMG   GP+GP G            MG P 
Sbjct: 1243 PPGSRGSP-GAPGPPGPPGSHVIGIKGDKGSMGH-PGPKGPPG--------TAGDMGPPG 1292

Query: 594  --SHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGP- 650
                P    L  P      +      G  G         P GP GPKG    PPG  G  
Sbjct: 1293 RLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKG----PPGVRGDP 1348

Query: 651  -------MPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPG----PG 699
                   +PG  G PG P  P + G P PP  G P   GP  P      RG PG    PG
Sbjct: 1349 GTLKIISLPGSPGPPGTPGEPGMQGEPGPP--GPPGNLGPCGP------RGKPGKDGKPG 1400

Query: 700  -PGPY-HRGRGGRGGNEPPPPPPPFRGARGGRSGGGPP 735
             PGP   +G  G  G   P       G +G R   G P
Sbjct: 1401 TPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
            sapiens]
          Length = 1670

 Score =  105 bits (261), Expect = 3e-22
 Identities = 131/386 (33%), Positives = 147/386 (38%), Gaps = 43/386 (11%)

Query: 538  EPGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPS 597
            EPG S G+  G  G    P L   MG  G    P  PG  G    E      G+P S  S
Sbjct: 1055 EPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPE------GAPGSPGS 1108

Query: 598  EELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFP--PGPGGPMPGPH 655
              L  +P           PHG LG   I     P G  GP G+  FP  PGP G + G  
Sbjct: 1109 PGLPGKPG----------PHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMG-IRGDQ 1157

Query: 656  GGPG--GPVGPR----LLGPPPPPRGGDPFWDGPGDPMRGGP-MRGGPGPGPGPYHRGRG 708
            G  G  GP G +    LL  PP PRG        GD  RG P   G PG        G  
Sbjct: 1158 GRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGD--RGAPGFPGLPGRKGAMGDAGPR 1215

Query: 709  GRGGNEPPPPPPPFRGA--RGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSG 766
            G  G E  P PP   GA   G     GPP  RG PG     G       G  G  G S G
Sbjct: 1216 GPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKG-SMG 1274

Query: 767  HRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPG-GGISGGSGHRPHEGPGGGMGA 825
            H   +GP G  G    P  G  G+ G  G   P   PG  G  G  G + + G  G +G 
Sbjct: 1275 HPGPKGPPGTAGDMGPP--GRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGP 1332

Query: 826  GGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRG-HDHRGPP-PHEHRGH 883
             G   P +GP G  G  G  +    PG  GP G      PG  G     GPP P  + G 
Sbjct: 1333 PGPIGP-KGPPGVRGDPGTLKIISLPGSPGPPG-----TPGEPGMQGEPGPPGPPGNLGP 1386

Query: 884  DGPGHGGGGHRGHDGGHSHGGDMSNR 909
             GP  G  G  G  G     G+  N+
Sbjct: 1387 CGP-RGKPGKDGKPGTPGPAGEKGNK 1411



 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 157/538 (29%), Positives = 187/538 (34%), Gaps = 130/538 (24%)

Query: 511 PYEPIPPKLIPLDEECSMDETPYVETLEPGGSGGSPDGAGGSKLPPVLA--------NLM 562
           PY P PP L  L     +   P  +     G  GSP   G + LP             L 
Sbjct: 480 PYIPGPPGLPGLPGLHGVKGIPGRQGA--AGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK 537

Query: 563 GSMGAGKGPQG----PGGGGINVQ---EILTSIMGSPNSH----PSEELLKQPDYSDKIK 611
           G  G    P+G    PG  G+  Q   + L  I G+P       P  EL    +  D+  
Sbjct: 538 GEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ-- 595

Query: 612 QMLVPHGLLG----PGPIANGFPPG-GPGGPKGMQHFPPGPGGPMP-------------- 652
               P G  G    PGP     PPG GP G  G+Q     PG P P              
Sbjct: 596 ---GPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652

Query: 653 ---GPHGGPGGPVGPRLLGPPPPP----RGGDPFWDGP-GDPMRGGPMRGGPGPGPGPYH 704
              GP G PG P  P   GPP  P    + GDP   GP G+P  G P  G PGP PGP  
Sbjct: 653 PVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEP--GIPGIGFPGP-PGP-- 707

Query: 705 RGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGG------GGHRPHEGPG 758
           +G  G  G +     P   G  G     G P  +G P   M GG       G R + G  
Sbjct: 708 KGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767

Query: 759 G-----------------GMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMG--------G 793
           G                 G+    G     GP G  G   R  EGP G+ G        G
Sbjct: 768 GEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKG 827

Query: 794 GGGHRPHEGPGG-------------GISGGSGHRPHEGPGGGMGAGG--------GHRPH 832
             G R   GP G             G +G  G   H+G  G +G  G        G    
Sbjct: 828 QQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGE 887

Query: 833 EGPGGSMGGSGGHRPHEGPGHGGPHGHR-PHDVPGHRGHDHRGPP----PHEHRGHDGPG 887
           +G  G MG  G   P   PG+ G  G R    +PG +G   RG P        +G+ GP 
Sbjct: 888 DGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKG--QRGTPGAKGEQGDKGNPGPS 945

Query: 888 H-----GGGGHRGHDGGHSHGGDMSNRPVCRHFMMKGNCRYENNCAFYHPGVNGPPLP 940
                 G  G  G  G   + G+  NR V     +KG            PG  GPP P
Sbjct: 946 EISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGL--------PGPAGPPGP 995



 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 129/414 (31%), Positives = 144/414 (34%), Gaps = 89/414 (21%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
            P G+ G+P   G   +P V     G+ GA KG QG  G                N  PSE
Sbjct: 905  PPGNPGTPGQRGSPGIPGVKGQ-RGTPGA-KGEQGDKG----------------NPGPSE 946

Query: 599  ELLKQPDYSDKIKQMLVPHGLLG----PGPIANGFPPGGPG--GPKGMQHFPPGPGGPMP 652
                    S  I     P GL G    PG   N   PG PG  G KG+    PGP GP P
Sbjct: 947  -------ISHVIGDKGEP-GLKGFAGNPGEKGNRGVPGMPGLKGLKGL----PGPAGP-P 993

Query: 653  GPHG---GPGGPVGPRLLGPPP-------------------PPRGGDPFWDG-------P 683
            GP G     G P  P L G P                    P R G P   G        
Sbjct: 994  GPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDK 1053

Query: 684  GDP-MRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG 742
            G+P    G   G PGP   P   G  G+ G    P PP   G  G     G P   G PG
Sbjct: 1054 GEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPG 1113

Query: 743  ----GGMVGGGGHRPHEGPGG--GMGNSSGHRPHEGPGGGMG-SGHRPHEGPGGSMGGGG 795
                 G +G  G +   GP G  G     G     GP G  G  G     GP G  G  G
Sbjct: 1114 KPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETG 1173

Query: 796  GHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGG 855
              R   GP G   G  G +   G  G  G         G  G+MG +G   P    G  G
Sbjct: 1174 LLRAPPGPRGN-PGAQGAKGDRGAPGFPGL-------PGRKGAMGDAGPRGPTGIEGFPG 1225

Query: 856  PHGHRPHDVPGHRGHDHRGPP-PHEHRGHDGPGHGGGGH----RGHDGGHSHGG 904
            P G     +PG  G  +RGPP      G  GP    G H    +G  G   H G
Sbjct: 1226 PPGLPGAIIPGQTG--NRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPG 1277



 Score = 77.8 bits (190), Expect = 4e-14
 Identities = 127/410 (30%), Positives = 148/410 (36%), Gaps = 95/410 (23%)

Query: 541 GSGGSPDGAGGSKLP-------PVLANLMGSMGAGKGPQGPGG--GGINVQEILTSIMGS 591
           GS GSP  AG +  P       P L    G  GA  GP G  G  G ++V   +    G 
Sbjct: 602 GSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA-PGPPGEAGPRGELSVSTPVPGPPGP 660

Query: 592 PN--SHPSEELLKQPDYSDKIKQMLVPHGLLGP----GPIANGFPPGGPGGPKGMQHFP- 644
           P    HP  +    P     + +   P GL GP    G    GFP  GP GPKG Q FP 
Sbjct: 661 PGPPGHPGPQ--GPPGIPGSLGKCGDP-GLPGPDGEPGIPGIGFP--GPPGPKGDQGFPG 715

Query: 645 ----------------------PG---------PGGP----MPGPHGGPG--GPVG-PRL 666
                                 PG         PGGP     PG  G  G  G +G P L
Sbjct: 716 TKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGL 775

Query: 667 LGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGAR 726
            G P  P  G+   DGP    RG P + GP    GP  R   G  G +  P     +G +
Sbjct: 776 PGLPGTP--GNEGLDGP----RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQ 829

Query: 727 GGRSGGGPPNGRGGPG------GGMVGGGGHRPHEGPGGGMGNSS--GHRPHEGPGGGMG 778
           G R   GP    G PG       G  G  G   H+G  G +G     G+    GP G  G
Sbjct: 830 GRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDG 889

Query: 779 ----SGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHE- 833
                G     GP G  G  G   P +    GI G  G R   G  G  G  G   P E 
Sbjct: 890 VIGMMGFPGAIGPPGPPGNPG--TPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEI 947

Query: 834 ----GPGGSMG-----GSGGHRPHEG-PGHGGPHGHR----PHDVPGHRG 869
               G  G  G     G+ G + + G PG  G  G +    P   PG RG
Sbjct: 948 SHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRG 997



 Score = 77.4 bits (189), Expect = 6e-14
 Identities = 121/412 (29%), Positives = 145/412 (35%), Gaps = 99/412 (24%)

Query: 539 PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGG----GGINVQEILTSIMGSPNS 594
           P GS G     G   LP              GPQGP G     G+   + +  I G P  
Sbjct: 56  PPGSPGQKGFTGPEGLP--------------GPQGPKGFPGLPGLTGSKGVRGISGLPGF 101

Query: 595 HPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGP 654
             S  L   P  +        P+GL+G           G  G KG Q FP      +PG 
Sbjct: 102 SGSPGLPGTPGNTG-------PYGLVGVP---------GCSGSKGEQGFPG-----LPGT 140

Query: 655 HGGPGGPVGPRLLGPP-PPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGN 713
            G PG P    L G    P +  D   D  GDP  G P   GP   PGP      G  G 
Sbjct: 141 LGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDP--GLPGAPGPQGLPGP-----PGFPGP 193

Query: 714 EPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGG-------------G 760
             PP PP F G  G     GP   +G  G  ++G  G R  +G  G             G
Sbjct: 194 VGPPGPPGFFGFPGAMGPRGP---KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTG 250

Query: 761 MGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMG-------GGGGHRPHEGPGG-----GIS 808
             N +  +  +G  G MG    P  GP G  G       G  G    +G  G     G  
Sbjct: 251 PDNRTDLKGEKGDKGAMGEPGPP--GPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFP 308

Query: 809 GGSGHRPHEGPGGGMGAGG--GHRPHEGPGGSMGGSGGHRPHE------GPGHGGPHGHR 860
           G  G + + G  G MG  G  G +   GP G  G +  +  ++       PG  GP G R
Sbjct: 309 GSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGAR 368

Query: 861 -------PHDVPGHRGHDHRGPPPHEHRGHDG-PG-HGGGGHRGHDGGHSHG 903
                  P  VPG  G    G      RG  G PG  G  G RG  G  + G
Sbjct: 369 GPQGPSGPPGVPGSPGSSRPG-----LRGAPGWPGLKGSKGERGRPGKDAMG 415



 Score = 77.4 bits (189), Expect = 6e-14
 Identities = 120/411 (29%), Positives = 138/411 (33%), Gaps = 109/411 (26%)

Query: 539 PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
           P G  G P G  GSK       L G++G    P  PG  G+  Q+      G+P      
Sbjct: 116 PYGLVGVP-GCSGSKGEQGFPGLPGTLGY---PGIPGAAGLKGQK------GAPAKEEDI 165

Query: 599 ELLKQPDYSDKIKQMLVPHGLLGP----GPIANGFPPG--------GPGGPKGMQHF--- 643
           EL  + D    +     P GL GP    GP+    PPG        GP GPKG       
Sbjct: 166 ELDAKGDPG--LPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVI 223

Query: 644 -------------PPGPGGPM----------------------------PGPHGGPGGPV 662
                        PPGP G +                            PGP G PG   
Sbjct: 224 GHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESY 283

Query: 663 GPRLLGPPPPPRGGDPFWDG-PGDP-------MRGGP----------MRGGPGP----GP 700
           G     P  P   G P  DG PG P        RG P           +G  GP    GP
Sbjct: 284 GSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGP 343

Query: 701 GPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPG-G 759
             Y+     +G    P PP P RGARG +   GPP   G PG    G  G      PG  
Sbjct: 344 TEYYDTYQEKGDEGTPGPPGP-RGARGPQGPSGPPGVPGSPGSSRPGLRG-----APGWP 397

Query: 760 GMGNSSGHRPHEG------PGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGG-----GIS 808
           G+  S G R   G      PG    +G     G  G  G  G     +GP G     G  
Sbjct: 398 GLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYL 457

Query: 809 GGSGHRPHEGPGGGMGAGGGHRPH-EGPGGSMGGSGGHRPHEGPGHGGPHG 858
           G  G    +GP G  G      P+  GP G  G  G H     PG  G  G
Sbjct: 458 GSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAG 508



 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 99/310 (31%), Positives = 106/310 (34%), Gaps = 81/310 (26%)

Query: 539  PGGSGGSP--DGAGGSKLPPVLANLMGSMGA--GKGPQGPGGGGINVQEILTSIMGSPNS 594
            P G  G+P   GA G +  P    L G  GA    GP+GP           T I G P  
Sbjct: 1178 PPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGP-----------TGIEGFPG- 1225

Query: 595  HPSEELLKQPDYSDKIKQMLVPHGLLG---PGPIANGFPPGGPGGPKGMQHFPPGPGGPM 651
                                 P GL G   PG   N  PPG  G P       PGP GP 
Sbjct: 1226 ---------------------PPGLPGAIIPGQTGNRGPPGSRGSPGA-----PGPPGP- 1258

Query: 652  PGPH-----GGPGGPVGPRLLGPP-------PPPRGGDPFWDGPGDPMRGGPMRGGPGPG 699
            PG H     G  G    P   GPP       PP R G      PG P   GP RG PG  
Sbjct: 1259 PGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLG-----APGTPGLPGP-RGDPGFQ 1312

Query: 700  PGPYHRGRGGR----GGNEPPPP-----PPPFRGARGGRSGGGPPNGRGGPGGGMVGGGG 750
              P  +G  G     G   PP P     PP  RG  G       P   G PG    G  G
Sbjct: 1313 GFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPG--TPGEPG 1370

Query: 751  HRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGG--GIS 808
             +   GP G  GN     P   PG     G     GP G  G  G  +   GP G  G+ 
Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKPG---KDGKPGTPGPAGEKGNKGS-KGEPGPAGSDGLP 1426

Query: 809  GGSGHRPHEG 818
            G  G R   G
Sbjct: 1427 GLKGKRGDSG 1436



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 93/307 (30%), Positives = 107/307 (34%), Gaps = 47/307 (15%)

Query: 633 GPGGPKGMQHFPPGPGGP----------MPGPHGGPGGPVGPRLLGPPPPPRG--GDPFW 680
           G  G KG + FP  PG P          +PGP G  G P  P L G     RG  G P +
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTG-SKGVRGISGLPGF 101

Query: 681 DG----PGDPMRGGP--MRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGR----- 729
            G    PG P   GP  + G PG       +G  G  G    P  P   G +G +     
Sbjct: 102 SGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAK 161

Query: 730 ------SGGGPPNGRGGPG-GGMVGGGGHRPHEGPGG--GMGNSSGHRPHEGPGGGMGSG 780
                    G P   G PG  G+ G  G     GP G  G     G     GP G MG  
Sbjct: 162 EEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGER 221

Query: 781 HRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMG 840
              H+G  G  G  G   P       ++G       +G  G  GA G   P  GP G  G
Sbjct: 222 VIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGP-PGPSGLPG 280

Query: 841 GSGGHRPHEGPGHGGPHGHRPHD-VPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDGG 899
            S G      PG  G  G    D VPG  G +          G  G   G  G  G DG 
Sbjct: 281 ESYGSE-KGAPGDPGLQGKPGKDGVPGFPGSE----------GVKG-NRGFPGLMGEDGI 328

Query: 900 HSHGGDM 906
               GD+
Sbjct: 329 KGQKGDI 335



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 73/218 (33%), Positives = 80/218 (36%), Gaps = 43/218 (19%)

Query: 539  PGGSGGSPDGAGGSKLPPV-----LANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPN 593
            P GS GSP GA G   PP      +    GSMG   GP+GP G            MG P 
Sbjct: 1243 PPGSRGSP-GAPGPPGPPGSHVIGIKGDKGSMGH-PGPKGPPG--------TAGDMGPPG 1292

Query: 594  --SHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGP- 650
                P    L  P      +      G  G         P GP GPKG    PPG  G  
Sbjct: 1293 RLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKG----PPGVRGDP 1348

Query: 651  -------MPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPG----PG 699
                   +PG  G PG P  P + G P PP  G P   GP  P      RG PG    PG
Sbjct: 1349 GTLKIISLPGSPGPPGTPGEPGMQGEPGPP--GPPGNLGPCGP------RGKPGKDGKPG 1400

Query: 700  -PGPY-HRGRGGRGGNEPPPPPPPFRGARGGRSGGGPP 735
             PGP   +G  G  G   P       G +G R   G P
Sbjct: 1401 TPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438


>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
          Length = 1497

 Score =  104 bits (260), Expect = 3e-22
 Identities = 111/336 (33%), Positives = 129/336 (38%), Gaps = 78/336 (23%)

Query: 627 NGFPPGGPG--------GPKGMQHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDP 678
           NG   G PG        GPKG + FP  PG P P  H GP GP G +          GDP
Sbjct: 562 NGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQK-------GSVGDP 614

Query: 679 FWDGP-GDPMRGGPM--RGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPP 735
             +GP G   R GPM  RG  GP PG   +G  G  G   P  PP   G+ G +   G P
Sbjct: 615 GMEGPMGQRGREGPMGPRGEAGP-PGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSP 673

Query: 736 NGRGGPG-------GGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGS-GHRPHEGP 787
             +G PG        G VG  G +  +GP G  G   G +  +GP G  G  G R   G 
Sbjct: 674 GPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPG-PKGDQGEKGPRGLTGEPGMRGLPGA 732

Query: 788 GGSMGGGGGHRP-----HEGPGG--GISGGSGHRPHEGPGGGMGAGGGHRPH-------- 832
            G  G  G   P     H+GP G  G++G  G R   GP G  G  G   P         
Sbjct: 733 VGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGT 792

Query: 833 ---------------------------EGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVP 865
                                       GP G  G  G   P   PG  GP G     +P
Sbjct: 793 PGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAG-----LP 847

Query: 866 GHRG-HDHRGPP-PHEHRGHDGPG-HGGGGHRGHDG 898
           GH+   + +GPP P   RG  GP   G  G RG  G
Sbjct: 848 GHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPG 883



 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 115/328 (35%), Positives = 130/328 (39%), Gaps = 63/328 (19%)

Query: 616 PHGLLG-PGPIANGFPPGGPGGPKGMQHFPPGPGGP-----------MPGPHG--GPGGP 661
           P G +G PGP  +   PG PG P  + H  PGP GP           M GP G  G  GP
Sbjct: 571 PKGDMGSPGPKGDRGFPGTPGIPGPLGH--PGPQGPKGQKGSVGDPGMEGPMGQRGREGP 628

Query: 662 VGPRLLGPPPPPRGGDPFWDG----------PGDPMRGGP--MRGGPGP--GPGPYH--- 704
           +GPR  G   PP  G+    G          PG P   GP    G PGP   PGP     
Sbjct: 629 MGPR--GEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQG 686

Query: 705 -RGR----GGRGGNEP--PPPPPPFRGARGGRSGGGPPNGRGGPGG-------GMVGGGG 750
            RG     G +G   P  PP P   +G +G R   G P  RG PG        G +G  G
Sbjct: 687 LRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAG 746

Query: 751 HRPHEGPGG--GMGNSSGHRPHEGPGGGMGS-GHRPHEGPGGSMG--GGGGHRPHEGPGG 805
              H+GP G  G+    G R   GP G  G  G    +GP G  G  G  G +   G  G
Sbjct: 747 PDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPG 806

Query: 806 GI--SGGSGHRPHEGPGGGMGAGGGHRPHEGPG-GSMGGSGGHRP----HEGPGHGGPHG 858
            I  S GS      GP G  GA G   P   PG     G  GH+        PG  GP G
Sbjct: 807 KIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRG 866

Query: 859 HRPHDVPGHRGHDHRGPPPHEHRGHDGP 886
                +PG  G   RGPP     G  GP
Sbjct: 867 PPGPSIPGPPG--PRGPPGEGLPGPPGP 892



 Score = 90.1 bits (222), Expect = 9e-18
 Identities = 131/435 (30%), Positives = 154/435 (35%), Gaps = 93/435 (21%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMG-----AGKGPQGPGGG-GINVQEILTSIMGSP 592
            P GS GSP G  G   P  L  L G +G       KGP GP G  G   ++    + G P
Sbjct: 666  PKGSSGSP-GPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEP 724

Query: 593  NSHPSEELLKQPDYSDKIKQMLVPHGLLGP-GPIANGFPPGGPG--------GPKGMQHF 643
                    + +P             G +GP GP  +  P G  G        GP G    
Sbjct: 725  GMRGLPGAVGEPGAK----------GAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGD 774

Query: 644  PPGPG--GPMPGPHGGPGGPVGPRLLGPPPPP-----RGGDPFWDGPGDPMRGGPMRGGP 696
            P  PG  GP  GP G PG P  P + G P  P       G      PG P   G M G P
Sbjct: 775  PGKPGLTGPQ-GPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAM-GPP 832

Query: 697  GPGPGPYHRGRGGRGGNEP------PPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGG 750
            GP   P   G  G  G++       PP PP  RG  G  S  GPP  RG PG G+ G   
Sbjct: 833  GPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGP-SIPGPPGPRGPPGEGLPG--- 888

Query: 751  HRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGG--GHRPHEG-PGGGI 807
              P   PG  + NS       GP G  G       GP G  G  G  GH+  +G PG   
Sbjct: 889  --PPGPPGSFLSNSETFL--SGPPGPPGP-----PGPKGDQGPPGPRGHQGEQGLPGFST 939

Query: 808  SGGSGHRPH-EGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGH-GGPHGHRPHDVP 865
            SG S    + +GP              GP G  G  G       PG  G P G  P +  
Sbjct: 940  SGSSSFGLNLQGP-------------PGPPGPQGPKGDKGDPGVPGALGIPSG--PSEGG 984

Query: 866  GHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDGGHSHGGDMSNRPVCRHFMMKGNCRYEN 925
                    GPP            G  G  G  G  S  G    + +  +          +
Sbjct: 985  SSSTMYVSGPP------------GPPGPPGPPGSISSSGQEIQQYISEYMQ-------SD 1025

Query: 926  NCAFYHPGVNGPPLP 940
            +   Y  GV GPP P
Sbjct: 1026 SIRSYLSGVQGPPGP 1040



 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 126/394 (31%), Positives = 148/394 (37%), Gaps = 73/394 (18%)

Query: 539 PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
           PG  G  P G  GS   P +   MG  G  +GP GP G             G P S    
Sbjct: 599 PGPQG--PKGQKGSVGDPGMEGPMGQRGR-EGPMGPRGEA-----------GPPGSGEKG 644

Query: 599 ELLKQPDYSDKIKQMLVPHGLLG-PGPI----ANGFP-PGGPGGPKGMQHFPPGPGGPMP 652
           E     +          PHG  G PG +    ++G P P GP GP G+Q      G  +P
Sbjct: 645 ERGAAGEPG--------PHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVG--LP 694

Query: 653 GPHG--GPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGR 710
           G  G  GP GP GP+          GD    GP    RG  + G PG    P   G  G 
Sbjct: 695 GVKGDKGPMGPPGPK----------GDQGEKGP----RG--LTGEPGMRGLPGAVGEPGA 738

Query: 711 GGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG-GGMVGGGGHRPHEGPGG--GMGNSSGH 767
            G   P  P   +G RG +   G P  RG PG  G  G  G    +GP G  G     G 
Sbjct: 739 KGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGI 798

Query: 768 RPHEGPGGGM----GSGHRPHEGPGGSMGGGGGHRPHEGPG-GGISGGSGHRP---HEGP 819
           +   G  G +    GS      GP G  G  G   P   PG  G +G  GH+     +GP
Sbjct: 799 KGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGP 858

Query: 820 GGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPP--- 876
            G  G      P   PG S+ G  G R   G G  GP G  P     +      GPP   
Sbjct: 859 PGPPG------PRGPPGPSIPGPPGPRGPPGEGLPGPPG-PPGSFLSNSETFLSGPPGPP 911

Query: 877 -PHEHRGHDGPGHGGGGHRGHDG--GHSHGGDMS 907
            P   +G  GP  G  GH+G  G  G S  G  S
Sbjct: 912 GPPGPKGDQGP-PGPRGHQGEQGLPGFSTSGSSS 944



 Score = 82.8 bits (203), Expect = 1e-15
 Identities = 96/291 (32%), Positives = 114/291 (39%), Gaps = 62/291 (21%)

Query: 538  EPGGSGG----SPDGAGGSKLPPVLANLMGSMGAGKGPQG-PGGGGINVQEILTSIMGSP 592
            EPG  G      PDG  G +    L  + G  G   GP G PG  G+   +    + G+P
Sbjct: 735  EPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGP-PGPSGDPGKPGLTGPQGPQGLPGTP 793

Query: 593  NSHPSEELLKQPDYSDKI-----KQMLV------PHGLLGPGPIANGFP-PGGPGGPKGM 640
                   +  +P    KI       ML       P G +GP P   G P P GP G  G 
Sbjct: 794  GR---PGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGP-PGPPGAPGPAGPAGLPGH 849

Query: 641  QHF-----PPGPGGP-------MPGPHGGPGGPVGPRLLGPPPPP----RGGDPFWDG-P 683
            Q       PPGP GP       +PGP  GP GP G  L GPP PP       + F  G P
Sbjct: 850  QEVLNLQGPPGPPGPRGPPGPSIPGP-PGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPP 908

Query: 684  GDPMRGGPMRGGPGPGPGPY-HRGRGGRGG------------NEPPPPPPPFRGARGGRS 730
            G P   GP +G  GP PGP  H+G  G  G             + PP PP  +G +G + 
Sbjct: 909  GPPGPPGP-KGDQGP-PGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKG 966

Query: 731  GGGPPNGRGGPGGGMVGGGGHRPH-EGPGGGMGNSSGHRPHEGPGGGMGSG 780
              G P   G P G   GG     +  GP G  G      P   PG    SG
Sbjct: 967  DPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPG------PPGPPGSISSSG 1011



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 99/393 (25%), Positives = 132/393 (33%), Gaps = 100/393 (25%)

Query: 539  PGGSGGSPDGA----GGSKLPPVLANLMGSMGAG---KGPQGPGG-GGINVQEILTSIMG 590
            PG  G S DG+      ++L   + + M S G      GP GP G  G + +E+L+ + G
Sbjct: 1111 PGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRG 1170

Query: 591  SPNSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGM---------- 640
            S                          G++GP       PPG PG P  +          
Sbjct: 1171 SEF-----------------------RGIVGPPG-----PPGPPGIPGNVWSSISVEDLS 1202

Query: 641  QHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGP 700
             +        +PGP G PG P GPR  GPP        +     D  R   +     P  
Sbjct: 1203 SYLHTAGLSFIPGPPGPPGPP-GPR--GPPGVSGALATYAAENSDSFRSELISYLTSPDV 1259

Query: 701  GPYHRGRGGRGGNEPPPPPPPFRG-----ARGGRSGGGPPNGRGGPG--GGMVGGGGHRP 753
              +  G  G  G + PP            +RG  S     + R G      M  GGG   
Sbjct: 1260 RSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAG 1319

Query: 754  HEGPGGGMGNSSGHR-PHE---GPGGGMGSGHR--PHEGPGGSMGGG-GGHRPH------ 800
              G GG  G ++G R P+    GPGGG G+      + G GG +G    G   +      
Sbjct: 1320 SLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVR 1379

Query: 801  -----------EGPGGGISGGSGHRPHEGPGG--------------------GMGAGGGH 829
                       +G    + G  G    +GP G                      GA  G 
Sbjct: 1380 VSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGP 1439

Query: 830  RPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPH 862
               +G  G+ G  G   P   PGH GP G R H
Sbjct: 1440 PGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGH 1472



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 71/285 (24%), Positives = 89/285 (31%), Gaps = 67/285 (23%)

Query: 464  PRPLVLPSPLVTPGSNSQERYIQAEREKGILQELFLNKESPHE------PDPEPYEPIPP 517
            P P   P P   PG +       AE       EL     SP        P   P    PP
Sbjct: 1217 PGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPP 1276

Query: 518  ---KLIPLDEECSMDETP------------YVETLEPGGSGGSPDGAGGSKLPPVLANLM 562
               +L+  D   S   +             Y  ++  GG G    GAGG+          
Sbjct: 1277 GDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGA---------F 1327

Query: 563  GSMGAGKGPQG----PGGGGINVQEILTSIMGSPNSHPSEELLKQPDYSD---KIKQMLV 615
            G     +GP G    PGGG     E    +          +     DY++   ++ + + 
Sbjct: 1328 GEAAGDRGPYGTDIGPGGGYGAAAE--GGMYAGNGGLLGADFAGDLDYNELAVRVSESMQ 1385

Query: 616  PHGLLGPGPIANGFPPGGPG--GPKGMQHF-----------------------PPGPGGP 650
              GLL         PPG PG  GP G+                          PPG  G 
Sbjct: 1386 RQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGE 1445

Query: 651  M--PGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMR 693
            M  PGP G  G P GP     PP PRG        GD +  G  R
Sbjct: 1446 MGTPGPKGDRG-PAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRR 1489



 Score = 38.1 bits (87), Expect = 0.039
 Identities = 63/261 (24%), Positives = 88/261 (33%), Gaps = 45/261 (17%)

Query: 555  PPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSEELLKQPDYSDKIKQML 614
            P V + ++G  G   GPQGP G    +    +   GS +S  S  + +   YS  +    
Sbjct: 1257 PDVRSFIVGPPGP-PGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMST-- 1313

Query: 615  VPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMP-----GPHGGPGGPVGPRLLGP 669
               G  G G +  G   G   G +G      GPGG        G + G GG +G      
Sbjct: 1314 ---GGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADF--- 1367

Query: 670  PPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGR 729
                  GD  ++     +     R G   G     +G  G+ G + PP       A    
Sbjct: 1368 -----AGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNV 1422

Query: 730  SGG------------GPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGM 777
            +              GPP  +G      +G  G +   GP G  G       H GP G  
Sbjct: 1423 TADLMDFFQTYGAIQGPPGQKGE-----MGTPGPKGDRGPAGPPG-------HPGPPGPR 1470

Query: 778  GSGHRPHEGPGGSMGGGGGHR 798
            G  H+  +G  G     G  R
Sbjct: 1471 G--HKGEKGDKGDQVYAGRRR 1489


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score =  104 bits (260), Expect = 3e-22
 Identities = 112/395 (28%), Positives = 136/395 (34%), Gaps = 49/395 (12%)

Query: 522 LDEECSMDETPYVETLEPGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINV 581
           L+E+ S +E+P +    P   G  P G    + PP           GK PQGP   G N 
Sbjct: 19  LNEDVSQEESPSLIAGNP--QGAPPQGGNKPQGPP--------SPPGK-PQGPPPQGGNQ 67

Query: 582 QEILTSIMGSPNSHPSEELLKQ------------PDYSDKIKQMLVPHGLLGPGPIANGF 629
            +      G P   P +   K             P   DK +    P G     P   G 
Sbjct: 68  PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGN 127

Query: 630 PPGGPGGPKGMQHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRG 689
            P GP  P G    PP  GG  P     PG P GP   G         P     G P +G
Sbjct: 128 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQG 187

Query: 690 GPMRGGPGPGPGPYHRGRGGRGGNEP--PPPP-----PPFRGARGGRSGGGPPNGRGGPG 742
           G    GP P PG   +G   +GGN+P  PPPP     PP +G    +S   PP   G P 
Sbjct: 188 GNQPQGPPPPPGK-PQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPP---GKPQ 243

Query: 743 GGMVGGG----GHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHR 798
           G    GG    G  P  G   G     G++P   P  G   G  P  G           +
Sbjct: 244 GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGK 303

Query: 799 PHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHG 858
           P   P  G +   G  P  G   G    GG++P   P          +P   P  GG   
Sbjct: 304 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG-------KPQGPPPQGGSKS 356

Query: 859 HRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGGGGH 893
                 PG      +GPP  E     GP    GG+
Sbjct: 357 RSARSPPG----KPQGPPQQEGNNPQGPPPPAGGN 387



 Score =  100 bits (250), Expect = 5e-21
 Identities = 95/310 (30%), Positives = 113/310 (36%), Gaps = 49/310 (15%)

Query: 624 PIANGFPPGGPGGPKGMQHFPPGPGGPMP-GPHGGPGGPVGP------RLLGPPPP--PR 674
           P   G  P GP  P G    PP  GG  P GP   PG P GP      +  GPPPP  P+
Sbjct: 40  PPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 99

Query: 675 GGDPFWDGP-----------GDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEP--PPPP-- 719
           G  P  D             G P +GG    GP P PG   +G   +GGN+P  PPPP  
Sbjct: 100 GPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK-PQGPPPQGGNKPQGPPPPGK 158

Query: 720 ---PPFRGARGGRSGGGPPNGRGGPGGGMVGGG----GHRPHEGPGGGMGNSSGHRPHEG 772
              PP +G    RS   PP   G P G    GG    G  P  G   G     G++P   
Sbjct: 159 PQGPPPQGDNKSRSSRSPP---GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 215

Query: 773 PGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPH 832
           P  G   G  P              +P   P  G +   G  P  G   G    GG++P 
Sbjct: 216 PPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 275

Query: 833 EGPGGS-------MGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDG 885
             P           GGS        PG       +P   P   G+  +GPPP   +    
Sbjct: 276 GPPPPGKPQGPPPQGGSKSRSSRSPPG-------KPQGPPPQGGNQPQGPPPPPGKPQGP 328

Query: 886 PGHGGGGHRG 895
           P  GG   +G
Sbjct: 329 PPQGGNKPQG 338



 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 95/309 (30%), Positives = 110/309 (35%), Gaps = 75/309 (24%)

Query: 539 PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
           P G    P   GG+K         G    GK PQGP   G N      S  G P   P  
Sbjct: 135 PPGKPQGPPPQGGNKP-------QGPPPPGK-PQGPPPQGDNKSRSSRSPPGKPQGPP-- 184

Query: 599 ELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPM-PGPHGG 657
                P   ++      P G   P     G PP G   P+G    PP PG P  P P G 
Sbjct: 185 -----PQGGNQ------PQGPPPPPGKPQGPPPQGGNKPQG----PPPPGKPQGPPPQGD 229

Query: 658 ---------PGGPVGP------RLLGPPPPPRGGDPFWDGP--GDPMRGGPMRGGP-GPG 699
                    PG P GP      +  GPPPPP  G P    P  G+  +G P  G P GP 
Sbjct: 230 NKSQSARSPPGKPQGPPPQGGNQPQGPPPPP--GKPQGPPPQGGNKPQGPPPPGKPQGPP 287

Query: 700 PGPYHRGRGGR------------GGNEP---PPPP-----PPFRGARGGRSGGGPPNGR- 738
           P    + R  R            GGN+P   PPPP     PP +G  G +  G PP G+ 
Sbjct: 288 PQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG--GNKPQGPPPPGKP 345

Query: 739 -GGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGH 797
            G P  G       R   G   G     G+ P   P    G+  +P   P G   G    
Sbjct: 346 QGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQG---- 401

Query: 798 RPHEGPGGG 806
            P   P GG
Sbjct: 402 -PPRPPQGG 409



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 59/212 (27%), Positives = 75/212 (35%), Gaps = 35/212 (16%)

Query: 684 GDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGG 743
           G P +GG    GP P P    +G   +GGN+P  PPPP      G+  G PP G   P G
Sbjct: 38  GAPPQGGNKPQGP-PSPPGKPQGPPPQGGNQPQGPPPP-----PGKPQGPPPQGGNKPQG 91

Query: 744 GMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGP 803
               G   +P   P  G  + S   P   P G    G    +GP    G   G  P    
Sbjct: 92  PPPPG---KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ--- 145

Query: 804 GGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHD 863
                   G++P   P  G   G    P +G   S            PG       +P  
Sbjct: 146 -------GGNKPQGPPPPGKPQGP---PPQGDNKSRSS------RSPPG-------KPQG 182

Query: 864 VPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRG 895
            P   G+  +GPPP   +    P  GG   +G
Sbjct: 183 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 214



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 73/261 (27%), Positives = 82/261 (31%), Gaps = 56/261 (21%)

Query: 504 PHEPDPE----PYEPIPPKLIPLDEECSMDETPYVETLEPGGSGGSPDGAGGSKLPPVLA 559
           P  P P+    P  P PP   P       D         PG   G P   G     P   
Sbjct: 201 PQGPPPQGGNKPQGPPPPGK-PQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGP--- 256

Query: 560 NLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSEELLKQPDYSDKIKQMLVPHGL 619
                   GK PQGP   G N  +      G P   P +     P    K +    P G 
Sbjct: 257 ----PPPPGK-PQGPPPQGGNKPQ------GPPP--PGKPQGPPPQGGSKSRSSRSPPGK 303

Query: 620 LGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPF 679
               P   G  P GP  P G    PP  GG  P     PG P G       PPP+GG   
Sbjct: 304 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG-------PPPQGGS-- 354

Query: 680 WDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRG 739
                   +    R  PG   GP       + GN P  PPPP        +GG P   + 
Sbjct: 355 --------KSRSARSPPGKPQGPPQ-----QEGNNPQGPPPP--------AGGNPQQPQA 393

Query: 740 GPGGGMVGGGGHRPHEGPGGG 760
            P G   G     P   P GG
Sbjct: 394 PPAGQPQG-----PPRPPQGG 409



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 57/190 (30%), Positives = 65/190 (34%), Gaps = 43/190 (22%)

Query: 539 PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598
           P G    P   GG+K         G    GK PQGP   G +      S  G P   P  
Sbjct: 259 PPGKPQGPPPQGGNKP-------QGPPPPGK-PQGPPPQGGSKSRSSRSPPGKPQGPP-- 308

Query: 599 ELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPM-PGPHGG 657
                P   ++      P G   P     G PP G   P+G    PP PG P  P P GG
Sbjct: 309 -----PQGGNQ------PQGPPPPPGKPQGPPPQGGNKPQG----PPPPGKPQGPPPQGG 353

Query: 658 ---------PGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRG 708
                    PG P GP      P   G +P   GP  P  G P +    P   P    R 
Sbjct: 354 SKSRSARSPPGKPQGP------PQQEGNNP--QGPPPPAGGNPQQPQAPPAGQPQGPPRP 405

Query: 709 GRGGNEPPPP 718
            +GG    PP
Sbjct: 406 PQGGRPSRPP 415



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 53/186 (28%), Positives = 62/186 (33%), Gaps = 27/186 (14%)

Query: 504 PHEPDPE----PYEPIPPKLIPLDEECSMDETPYVETLEPGGSGGSPDGAGGSKLPPVLA 559
           P  P P+    P  P PP   P          P  +   P G    P   GGSK      
Sbjct: 242 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP--QGPPPPGKPQGPPPQGGSKS----- 294

Query: 560 NLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSEELLKQPDYSDKIKQMLVPHGL 619
               S      PQGP   G N  +      G P   P       P   +K +    P   
Sbjct: 295 --RSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP-------PQGGNKPQGPPPPGKP 345

Query: 620 LGPGPIANG------FPPGGPGGPKGMQ-HFPPGPGGPMPGPHGGPGGPVGPRLLGPPPP 672
            GP P           PPG P GP   + + P GP  P  G    P  P   +  GPP P
Sbjct: 346 QGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP 405

Query: 673 PRGGDP 678
           P+GG P
Sbjct: 406 PQGGRP 411



 Score = 37.4 bits (85), Expect = 0.066
 Identities = 33/129 (25%), Positives = 43/129 (33%), Gaps = 18/129 (13%)

Query: 773 PGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPH 832
           P G    G    +GP    G     +P   P  G +   G  P  G   G    GG++P 
Sbjct: 36  PQGAPPQGGNKPQGPPSPPG-----KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 90

Query: 833 EGP------GGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGP 886
             P      G    G     P   PG       +P   P   G+  +GPPP   +    P
Sbjct: 91  GPPPPGKPQGPPPQGDKSRSPRSPPG-------KPQGPPPQGGNQPQGPPPPPGKPQGPP 143

Query: 887 GHGGGGHRG 895
             GG   +G
Sbjct: 144 PQGGNKPQG 152


>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
          Length = 684

 Score =  104 bits (259), Expect = 4e-22
 Identities = 136/408 (33%), Positives = 154/408 (37%), Gaps = 71/408 (17%)

Query: 539 PGGSGGSP--DGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMG-----S 591
           P G  G P  DG  G   PP L    G  GA   P  PG  G+     +  + G      
Sbjct: 36  PPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPG 95

Query: 592 PNSHPSEELLKQPDYSDKIKQMLVPHGLLGP-GPIANGFPPGG-----PGGPKGMQHFPP 645
           P   P E     P         L   GL GP G      PPGG     P GP G+    P
Sbjct: 96  PKGAPGERGSLGPPGPPG----LGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGL-P 150

Query: 646 GPGGPMPGPHGGPGG-PVG------PRLLGPPPPPRGGDPFWDGP-------GDPMRGGP 691
           GP GP PGP G PG  P G      P +  P PP   G P + GP       G+  + G 
Sbjct: 151 GPPGP-PGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGE 209

Query: 692 MRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRG-----GPGG--G 744
            +G PGP PGP   G  G  G + P      RG RG     GPP  RG     GP G  G
Sbjct: 210 -KGDPGP-PGP--AGLPGSVGLQGP------RGLRGLPGPLGPPGDRGPIGFRGPPGIPG 259

Query: 745 MVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPG 804
             G  G R   GP G  G   G     GP G  G       GP G  G  G    +  PG
Sbjct: 260 APGKAGDRGERGPEGFRG-PKGDLGRPGPKGTPGVA-----GPSGEPGMPGKDGQNGVPG 313

Query: 805 ----GGISGGSGHRPHEGPGG--GMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHG 858
                G +G +G    +GP G  G+    G +  +G  G  G  G   P   PG  G  G
Sbjct: 314 LDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAG 373

Query: 859 HRPHDVPGHRGH-DHRGPPPHEHRGHDGPGHGGGGHRGHDGGHSHGGD 905
                +PG RG   HRG       G  GP  G  G RG  G     GD
Sbjct: 374 -----MPGERGEAGHRGSA--GALGPQGP-PGAPGVRGFQGQKGSMGD 413



 Score = 92.8 bits (229), Expect = 1e-18
 Identities = 98/280 (35%), Positives = 110/280 (39%), Gaps = 46/280 (16%)

Query: 645 PGPGGPMPGPHGGPG-----GPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPG 699
           PGP GP PGP G PG     G  GP  L  PP P+G       PG P       G PG  
Sbjct: 31  PGPPGP-PGPPGKPGQDGIDGEAGPPGLPGPPGPKG------APGKP-------GKPGEA 76

Query: 700 PGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGG 759
             P   G  G  G + PP P   +GA G R   GPP   G  G G+ G  G     GP G
Sbjct: 77  GLPGLPGVDGLTGRDGPPGP---KGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPG 133

Query: 760 GMG-----NSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGG-----GISG 809
           G+G       SG     GP G  G    P   P G+           GP G     G  G
Sbjct: 134 GIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKG 193

Query: 810 GSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRG 869
            +G++  +G  G  G  G   P  GP G  G  G   P    G  GP G      PG RG
Sbjct: 194 PTGYKGEQGEVGKDGEKGDPGP-PGPAGLPGSVGLQGPRGLRGLPGPLG-----PPGDRG 247

Query: 870 H-DHRGPPPHEHRGHDG-PGHGGG-GHRGHDGGHSHGGDM 906
               RGPP     G  G PG  G  G RG +G     GD+
Sbjct: 248 PIGFRGPP-----GIPGAPGKAGDRGERGPEGFRGPKGDL 282



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 136/451 (30%), Positives = 156/451 (34%), Gaps = 114/451 (25%)

Query: 547 DGAGGSKLPPVLANLMGSMGAGKGPQG----------PGGGGINVQEILTSIMGSPNSHP 596
           DG  G   PP  A L GS+G  +GP+G          PG  G         I G+P    
Sbjct: 207 DGEKGDPGPPGPAGLPGSVGL-QGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPG--- 262

Query: 597 SEELLKQPDYSDKIKQMLVPHGLLGP-GPIANGFPPGGPG--GPKGMQHFPPGPG-GPMP 652
                K  D  ++      P G  GP G +    P G PG  GP G    P   G   +P
Sbjct: 263 -----KAGDRGER-----GPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVP 312

Query: 653 GPHGGPG--------GPVGPRLLGPPPPPRGGDPFWDGP----GDPMRGGPMRGGPG-PG 699
           G  G  G        G  GP  L P  P R G     G     G+    GP  G PG PG
Sbjct: 313 GLDGQKGEAGRNGAPGEKGPNGL-PGLPGRAGSKGEKGERGRAGELGEAGPS-GEPGVPG 370

Query: 700 ----PGPY----HRGRGGRGGNEPPPPPPPFRG------------------ARGGRSGGG 733
               PG      HRG  G  G + PP  P  RG                   RG     G
Sbjct: 371 DAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRG 430

Query: 734 PPNGRGGPGG-----GMVGGGGHRPHEGPGGGMG--NSSGHRPHEGPGGGMG----SGHR 782
            P G  GP G     G  G  G +   GP G +G    SG R   GP G  G    SG +
Sbjct: 431 -PGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQ 489

Query: 783 PHEGPGGSMGGGG-------------------GHRPHEGPGGGISGG----SGHRPHEGP 819
              GP G +G  G                     R  E  GG IS      + H      
Sbjct: 490 GVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLA 549

Query: 820 GGGMGAGGGHRP--HEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHD-HRGPP 876
            G +G  G   P    GP GS+G  G   P   PG+ GP G      PG RG+   RG  
Sbjct: 550 PGSIGRPGPAGPPGPPGPPGSIGHPGARGP---PGYRGPTGELGD--PGPRGNQGDRGDK 604

Query: 877 PHEHRGHDGP--GHGGGGHRGHDGGHSHGGD 905
                G DGP    G  G +G  G    G D
Sbjct: 605 GAAGAGLDGPEGDQGPQGPQGVPGTSKDGQD 635



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 99/339 (29%), Positives = 117/339 (34%), Gaps = 74/339 (21%)

Query: 537 LEPGGSGGSPDGAGGSKLPPVL--ANLMGSMGAGKGPQGPGGG-GINVQEILTSIMGSPN 593
           L   G  G P   G + +P     A   GS GA  GPQGP G  G+   +     MG P 
Sbjct: 357 LGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGA-LGPQGPPGAPGVRGFQGQKGSMGDPG 415

Query: 594 SHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMPG 653
                              +  P GL G         PGG  GPKG Q      G  +PG
Sbjct: 416 -------------------LPGPQGLRGD---VGDRGPGGAAGPKGDQGIAGSDG--LPG 451

Query: 654 PHG--GPGGPVGPR-------LLGPPPP--PRGGDPFWDGPGDPMRGGPM--RGGPGPGP 700
             G  GP G VGP+        LGP     P G       PG P   GP+  +G PG   
Sbjct: 452 DKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPP---GPLGLQGVPGV-- 506

Query: 701 GPYHRGRGGRGGNEPPPP----------------------PPPFRGARGGRSGGGPPNGR 738
            P   G+ G  G E                           P   G+ G     GPP   
Sbjct: 507 -PGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPP 565

Query: 739 GGPGG-GMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGH 797
           G PG  G  G  G   + GP G +G+  G R ++G  G  G+     +GP G  G  G  
Sbjct: 566 GPPGSIGHPGARGPPGYRGPTGELGDP-GPRGNQGDRGDKGAAGAGLDGPEGDQGPQG-- 622

Query: 798 RPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPG 836
            P   PG    G  G     GP G  G  G       PG
Sbjct: 623 -PQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 116/407 (28%), Positives = 142/407 (34%), Gaps = 102/407 (25%)

Query: 539 PGGSGGSPDGAG--GSKLPPVLANLMGSMGAGKGPQG----------PGGGGINVQEILT 586
           P G  G+P  AG  G + P       G +G   GP+G          PG  G + Q  + 
Sbjct: 254 PPGIPGAPGKAGDRGERGPEGFRGPKGDLGR-PGPKGTPGVAGPSGEPGMPGKDGQNGVP 312

Query: 587 SIMGSP-----NSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQ 641
            + G       N  P E   K P+    +       G  G    A      GP G  G+ 
Sbjct: 313 GLDGQKGEAGRNGAPGE---KGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGV- 368

Query: 642 HFPPGPGGPMPGPHG-----GPGGPVGPRLLGPPPPP--RG--------GDPFWDGPGDP 686
              PG  G MPG  G     G  G +GP+  GPP  P  RG        GDP   GP   
Sbjct: 369 ---PGDAG-MPGERGEAGHRGSAGALGPQ--GPPGAPGVRGFQGQKGSMGDPGLPGP-QG 421

Query: 687 MRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPP------------PPPFRGARG--GRSGG 732
           +RG     GPG   GP  +G  G  G++  P             P    G+RG  G  G 
Sbjct: 422 LRGDVGDRGPGGAAGP--KGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGT 479

Query: 733 GPPNGRGGPGG--------GMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGM------- 777
             PNG  G  G        G+ G  G     G  G  G  +  +      GGM       
Sbjct: 480 QGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQ 539

Query: 778 -----------GSGHRPHE-------GPGGSMGGGGGHRP--HEGPGGGISGGSGHRPHE 817
                      GS  RP         GP GS+G  G   P  + GP G + G  G R ++
Sbjct: 540 LAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGEL-GDPGPRGNQ 598

Query: 818 GPGGGMGAGG-GHRPHEGPGGSMG-----GSGGHRPHEGPGHGGPHG 858
           G  G  GA G G    EG  G  G     G+        PG  GP G
Sbjct: 599 GDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPG 645



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 95/330 (28%), Positives = 110/330 (33%), Gaps = 93/330 (28%)

Query: 537 LEPGGSGGSP-----DGAGGSKLPPVLANLMGSMGAGKGPQGPGGG-GINVQEILTSIMG 590
           L P G  G+P      G  GS   P L    G  G   G +GPGG  G    + +    G
Sbjct: 390 LGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRG-DVGDRGPGGAAGPKGDQGIAGSDG 448

Query: 591 SPNSHPSEELLKQPDYSDKIKQMLVPHGLLGP----GPIANGFPPG--GPGGPKGMQHFP 644
            P                  K  L P GL+GP    G      P G  GP G  G+Q  P
Sbjct: 449 LPGD----------------KGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVP 492

Query: 645 PGPGGPMPGPHGGPGGPVGPRLLGPPPPPR------------GG--------------DP 678
               GP PGP G  G P  P + G P  P             GG               P
Sbjct: 493 ----GP-PGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKP 547

Query: 679 FWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNG- 737
               PG   R GP  G PGP   P   G  G  G      PP +RG  G     GP    
Sbjct: 548 L--APGSIGRPGPA-GPPGPPGPPGSIGHPGARG------PPGYRGPTGELGDPGPRGNQ 598

Query: 738 -----RGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMG 792
                +G  G G+ G  G +  +GP G  G S      +G  G  G       GP G  G
Sbjct: 599 GDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSK-----DGQDGAPG-----EPGPPGDPG 648

Query: 793 GGGGHRPHEGPG--------GGISGGSGHR 814
             G       PG        G + GG G +
Sbjct: 649 LPGAIGAQGTPGICDTSACQGAVLGGVGEK 678


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score =  103 bits (258), Expect = 6e-22
 Identities = 129/387 (33%), Positives = 156/387 (40%), Gaps = 54/387 (13%)

Query: 538  EPGGSGGSPDGAGGSK----LP----PVLANLMGSMGAGKGPQGPGGGGINVQEILTSIM 589
            +PG  G  P G  GSK    LP    P+  NL+GS G    P  PG  G++  +    + 
Sbjct: 930  QPGLPG--PTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLP 987

Query: 590  GSPNSH--PSEELLKQPDYSDKIKQMLVPHGLLGP----GPIAN-GFP-PGGPGGPKGMQ 641
            G P       +  L  P        +    GL+GP    G I + GFP P G  GP G  
Sbjct: 988  GDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPS 1047

Query: 642  HFPPGPGGP-MPGPHGGPGGPVGPRLLGPP--PPPRGGDPFWDGPGDPMRGGPMRGGPG- 697
              P  PG P +PG  G  G P G   +G P  P P+G       PG+P   G + G PG 
Sbjct: 1048 GVPGQPGSPGLPGQKGDKGDP-GISSIGLPGLPGPKGEPGLPGYPGNPGIKGSV-GDPGL 1105

Query: 698  PG-PG-PYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGG-GMVGGGGHRPH 754
            PG PG P  +G+ G  G    P PP      G +   GPP   G PG  G VGGGGH   
Sbjct: 1106 PGLPGTPGAKGQPGLPGFPGTPGPP------GPKGISGPPGNPGLPGEPGPVGGGGHPGQ 1159

Query: 755  EGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGG--GISGGSG 812
             GP G  G   G     GP G  G   +P  G             + GP G  G+SG  G
Sbjct: 1160 PGPPGEKGKP-GQDGIPGPAGQKGEPGQPGFG-------------NPGPPGLPGLSGQKG 1205

Query: 813  HRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDH 872
                 G  G  G  G     +G  G  G  G   P   PG  GP    P   PG +G   
Sbjct: 1206 DGGLPGIPGNPGLPGP----KGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPG 1261

Query: 873  RGPPPHEHRGHDGPGHGG-GGHRGHDG 898
            R   P        PG+GG  G +G+ G
Sbjct: 1262 RPGLPGPEGPPGLPGNGGIKGEKGNPG 1288



 Score =  103 bits (256), Expect = 1e-21
 Identities = 152/476 (31%), Positives = 180/476 (37%), Gaps = 87/476 (18%)

Query: 470  PSPLVTPGSNSQERYIQAEREKGILQELFL----NKESPHEPDPEPYEPIPPKLIPLDEE 525
            P P   PG   Q   I     KG + ++        E P  P   P +P  P L P  + 
Sbjct: 1005 PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGL-PGQKG 1063

Query: 526  CSMDETPYVETL----------EPG--GSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQG 573
               D  P + ++          EPG  G  G+P G  GS   P L  L G+ GA KG  G
Sbjct: 1064 DKGD--PGISSIGLPGLPGPKGEPGLPGYPGNP-GIKGSVGDPGLPGLPGTPGA-KGQPG 1119

Query: 574  ----------PGGGGINVQEILTSIMGSPN-----SHPSEELLKQPDYSDKIKQMLVP-- 616
                      PG  GI+       + G P       HP +     P    K  Q  +P  
Sbjct: 1120 LPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQP--GPPGEKGKPGQDGIPGP 1177

Query: 617  ---HGLLGPGPIANGFPPGGPG--GPKGMQHFPPGPGGP-MPGP------HGGPGGPVGP 664
                G  G     N  PPG PG  G KG    P  PG P +PGP      HG PG     
Sbjct: 1178 AGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPG----- 1232

Query: 665  RLLGPPPPPRGGDPFWDGP-GDPMRGGP--MRGGPGPGPGPYHRGRGGRGGNEPPPPPPP 721
             + GPP PP    P  +GP G+P   GP    G PGP   P   G GG  G +  P  P 
Sbjct: 1233 -VQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPG 1291

Query: 722  FRGARGGRSGGGPPNGRGGPG-GGMVGGGGHRPHEGPGG--GMGNSSGHRPHEGPGGGMG 778
              G  G +   GPP  +G PG  G+ G  G     G  G  GM   SG     GP G  G
Sbjct: 1292 LPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPG 1351

Query: 779  SGHRPHEGPGGSMGGGGGHRPHEGPGG--GISGGSGHRPHEGPGGGMGAGGGHRPHEGPG 836
                P  GP G  G  G     +G  G  GI G  G +   GP G  G  G   P   PG
Sbjct: 1352 LIGPP--GPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPG 1409

Query: 837  GS----MGGSGGHRPHEG-PGHGGPHGHRPHDVPGHRGHDHRGPP-PHEHRGHDGP 886
             +      G+GG +   G PG            PG RG D  GPP P   +G  GP
Sbjct: 1410 RNGLPGFDGAGGRKGDPGLPGQ-----------PGTRGLD--GPPGPDGLQGPPGP 1452



 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 165/527 (31%), Positives = 185/527 (35%), Gaps = 139/527 (26%)

Query: 538  EPGGSG----------GSP--DGAGGSKLPPVLANLMGSMGAG-----------KGPQGP 574
            +PG  G          GSP   GA G   PP    L G  GA             GP GP
Sbjct: 847  DPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGP 906

Query: 575  GGG-GINVQEILTSIMGSPNSHPSEELLKQPDYSDKI--KQMLVPHGLLG-PGPI----- 625
             G  GI  +       G P     + L  QP        K      GL G PGP+     
Sbjct: 907  PGPLGIPGRS------GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960

Query: 626  ----ANGFP--PGGPG--GPKGMQHFPPGPGGP----------MPGPHGGPGGPVGPRLL 667
                  G P  PG PG  GPKG Q  P  PG P           PGP G PG P  P L+
Sbjct: 961  GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI 1020

Query: 668  GPP-----------PPPRG--------------------------GDPFWDGPGDPMRGG 690
            GPP           P P+G                          GDP     G P   G
Sbjct: 1021 GPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG 1080

Query: 691  PMRGGPG-PG-PG----------PYHRGRGGRGGNEPPPPPPPFRGARG--GRSG-GGPP 735
            P +G PG PG PG          P   G  G  G +  P  P F G  G  G  G  GPP
Sbjct: 1081 P-KGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPP 1139

Query: 736  NGRGGPG-GGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRP---HEGPGGSM 791
               G PG  G VGGGGH    GP G  G   G     GP G  G   +P   + GP G  
Sbjct: 1140 GNPGLPGEPGPVGGGGHPGQPGPPGEKG-KPGQDGIPGPAGQKGEPGQPGFGNPGPPGLP 1198

Query: 792  GGGGGHRPHEGPGG--GISGGSGHRPHEGPGGGMGAGGGHRPHEGPG-------GSMGGS 842
            G  G     +G GG  GI G  G    +G  G  G  G   P   PG       G  G  
Sbjct: 1199 GLSG----QKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNP 1254

Query: 843  GGHRPHEGPGHGGPHGHRPHDVPGHRG-HDHRGPPPHEH-------RGHDGPGHGGGGHR 894
            G   P   PG  GP G  P  +PG+ G    +G P           +G  GP  G  G+ 
Sbjct: 1255 GPQGPPGRPGLPGPEG--PPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGP-PGLQGNP 1311

Query: 895  GHDGGHSHGGDMSNRPVCRHFMMKGNCRYENNCA-FYHPGVNGPPLP 940
            G  G +   GD     V     MKG      +      PG+ GPP P
Sbjct: 1312 GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1358



 Score = 98.2 bits (243), Expect = 3e-20
 Identities = 127/372 (34%), Positives = 145/372 (38%), Gaps = 63/372 (16%)

Query: 539 PGGSG--GSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHP 596
           PG  G  GS    G     P +    G +G+   P  PG  G   Q+ L  + G P   P
Sbjct: 535 PGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPG-PKGEP 593

Query: 597 SEELLKQPDYSDKIKQMLVPHGLLGP-GPIANGFPPGGPGGPKGMQHFPPGPGGP-MPGP 654
                K          +    G +GP GP   GF P GP G KG+Q     PG P +PGP
Sbjct: 594 GGITFKGERGPPGNPGLPGLPGNIGPMGP--PGFGPPGPVGEKGIQGVAGNPGQPGIPGP 651

Query: 655 HGGPG------------------GPVG----PRLLGPPP----PPRGGDPFWDGPGDPMR 688
            G PG                  G VG    P L G P     P   G+P   G G P  
Sbjct: 652 KGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP 711

Query: 689 GGPMRGGPG-PGPGPYHRGRGGRGGNEPPPPPPPFRGARG--GRSGGGPPNGRGGPG-GG 744
            GP +G PG PGP P   G  GR G E PP PP F G +G  G +  GPP   G PG  G
Sbjct: 712 PGP-KGFPGIPGP-PGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG 769

Query: 745 MVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEG-- 802
            +G  G R   GP              GP G  G    P  GP G +G  G   P     
Sbjct: 770 ALGPKGDRGFPGP-------------PGPPGRTGLDGLP--GPKGDVGPNGQPGPMGPPG 814

Query: 803 -PGGGISGGSGHRPHEGPGGGMGAGG--GHRPHEGPGG-SMGGSGGHRPHEG-PGHGGPH 857
            PG G+ G  G     GP G  G  G  G +   GP G  + G  G R   G PG  GP 
Sbjct: 815 LPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPI 874

Query: 858 GHRPHDVPGHRG 869
           G  P   PG  G
Sbjct: 875 G--PPGSPGLPG 884



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 92/274 (33%), Positives = 105/274 (38%), Gaps = 31/274 (11%)

Query: 633 GPGGPKGMQHFPPGPGGP-MPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDG-PGDPMRGG 690
           G  G KG + FP   G P +PG   GP GP GPR          G    DG PG P   G
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPG-FPGPEGPPGPR----------GQKGDDGIPGPPGPKG 90

Query: 691 PMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG-GGMVGGG 749
            +RG PG    P   G  G  G++  P P    G  G +   G P   G PG  G  G  
Sbjct: 91  -IRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPP 149

Query: 750 GHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISG 809
           G    +G  G +  SS   P   PG     G +   GP G  G  G   P      G+ G
Sbjct: 150 GIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGP-----PGLMG 204

Query: 810 GSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRG 869
             G     GP G MG        +GP G  G  G   P   PG       RP DV   +G
Sbjct: 205 PPGPPGLPGPKGNMGLN-----FQGPKGEKGEQGLQGPPGPPGQISEQ-KRPIDVEFQKG 258

Query: 870 HD----HRGPP-PHEHRGHDGPGHGGGGHRGHDG 898
                  RGPP P   RG  GP  G  G +G  G
Sbjct: 259 DQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQG 292



 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 132/435 (30%), Positives = 159/435 (36%), Gaps = 80/435 (18%)

Query: 539 PGGSG-GSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQ-----EILTSIMGSP 592
           PG  G   P G  G   PP    LMG  G    P   G  G+N Q     +    + G P
Sbjct: 179 PGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPP 238

Query: 593 NSHPSEELLKQP-DYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGM--QHFPPGPGG 649
                    K+P D   +     +P     PGP     PPG PGG KG   +   PG  G
Sbjct: 239 GPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRG 298

Query: 650 PMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGP--MRGGPGPGPGP----- 702
             PG  G  G P      G P  P  GDP +  PG+P R G    +G  GP PGP     
Sbjct: 299 -KPGKDGENGQP------GIPGLP--GDPGY--PGEPGRDGEKGQKGDTGP-PGPPGLVI 346

Query: 703 YHRGRG---GRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGG---------GMVGGGG 750
              G G   G  GN   P  P  +G RG     GPP   G PG          G  G  G
Sbjct: 347 PRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERG 406

Query: 751 HRPHEGPGG-------GMGNSSGHRPHEGPGGGMGSGHRPHE--------GPGGSMGGGG 795
            +  EGP G       G+    G     GP G  G    P +        GP GS G  G
Sbjct: 407 QKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKG 466

Query: 796 --GHRPHEGP---------GGGISGGSGHRPHEGPGGGMGAGG--GHRPHEGPGGSMGGS 842
             G +  +G          G GISG  G     G  G  G+ G  G +  +G  G+ G  
Sbjct: 467 LQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPK 526

Query: 843 GGHRPHEGPGHGGPHGHR--PHDV---PGHRGH--DHRGPPPHEHRGHDG-PGHGG---- 890
           G       PG  G  G +  P D+   PG +G   +   P      G  G PG  G    
Sbjct: 527 GLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGL 586

Query: 891 GGHRGHDGGHSHGGD 905
            G +G  GG +  G+
Sbjct: 587 PGPKGEPGGITFKGE 601



 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 101/341 (29%), Positives = 120/341 (35%), Gaps = 66/341 (19%)

Query: 616 PHGLLGPGPIANGFPPGGPG--GPKGMQHFPPGPGGPMPGPHG-----------GPGGPV 662
           P GL GP   A   PPG PG  G +G +     PG  +PGP G           GP GP 
Sbjct: 381 PPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA 440

Query: 663 GPRL--------LGPPPPPRG----------------GDPFWDGPGDPMRGGPMRGG-PG 697
           GP +         GPP PP                  GD  ++  G  + G P + G PG
Sbjct: 441 GPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPG 500

Query: 698 -PGPG-----PYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGG-----GMV 746
            PGP      P  +G  G+ G   P   P   GA G     G P  +G PG      GM 
Sbjct: 501 LPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPG---APGFPGSKGEPGDILTFPGMK 557

Query: 747 GGGGHRPHEGPGG--GMGNSSGH-------RPHEGPGGGMGSGHRPHEGPGGSMGGGGGH 797
           G  G     G  G  G+  + G         P   PGG    G R   G  G  G  G  
Sbjct: 558 GDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNI 617

Query: 798 RPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPH 857
            P   PG G  G  G +  +G  G  G  G   P   PG ++   G       PG  G  
Sbjct: 618 GPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDV 677

Query: 858 GHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDG 898
           G     +PG  G   +   P        PG  G G  G  G
Sbjct: 678 G-----LPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPG 713



 Score = 77.4 bits (189), Expect = 6e-14
 Identities = 109/354 (30%), Positives = 125/354 (35%), Gaps = 71/354 (20%)

Query: 616 PHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGP-------MPGP------------HG 656
           P G  G   I     P G  GP G+  FP  PG P        PGP             G
Sbjct: 73  PRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERG 132

Query: 657 GPGGPVGPRLLGPPPPP----RGGDP------FWDGP-GDPMRGGP--MRGGPGPGPGPY 703
            PG P  P L GPP PP      G+P         GP G+P   GP  ++G PGP   P 
Sbjct: 133 FPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPG 192

Query: 704 HRGRGGRGGNEPPPPPPPFRGARG--GRSGGGPPNGRG-----GPGG------------- 743
             G  G  G   PP PP   G +G  G +  GP   +G     GP G             
Sbjct: 193 PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252

Query: 744 -----GMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGS-GHRPHEGPGGSMGGGGGH 797
                G  G  G R   GP G  G        +G  G  G  G R   G  G  G  G  
Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312

Query: 798 RPHEGPG-GGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGP 856
                PG  G  G  G +  +G  G  G  G   P  G G ++G  G       PG  G 
Sbjct: 313 GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372

Query: 857 HG----HRPHDVPGHRGHDHRGPP-----PHE--HRGHDG-PGHGGGGHRGHDG 898
            G      P  +PG  G    GPP     P E   +G +G PG    G  G DG
Sbjct: 373 RGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG 426



 Score = 77.0 bits (188), Expect = 8e-14
 Identities = 134/459 (29%), Positives = 162/459 (35%), Gaps = 141/459 (30%)

Query: 539  PGGSGGSPDGAGGSKLPPVLANLMGSMGAG-----KGPQGPGGGGINVQEILTSIMGSPN 593
            PG  G       G   PP L    G++G        GP GP G         T + G P 
Sbjct: 745  PGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGR--------TGLDGLPG 796

Query: 594  SHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPG----GPKGMQHFPPGPGG 649
                             K  + P+G   PGP+    PPG PG    GP G    PPG  G
Sbjct: 797  P----------------KGDVGPNGQ--PGPMG---PPGLPGIGVQGPPG----PPGIPG 831

Query: 650  PM--PGPHGGPG---GPVGPRLLGPPPPPRGGDPFWDG----------PGDPMRGGP--- 691
            P+  PG HG PG    P  P L  P PP   G P   G          PG P + G    
Sbjct: 832  PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGF 891

Query: 692  --------MRGGPGPGPGPYH----------RGRGGRGGNEPPPPPPPFRGARGGRSGGG 733
                    M G PGP PGP            +G  G  G    P P   +G++G     G
Sbjct: 892  PGTKGEMGMMGPPGP-PGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPG 950

Query: 734  PP-----------NGRGGPG-GGMVGGGGHRPHEGPGG--GMGNSSGHRPHEGPGGGMGS 779
            PP             +G PG  G+ G  G + ++G  G  G    SG     GP G  G+
Sbjct: 951  PPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN 1010

Query: 780  GHRPHE----GPGGSMG-----GGGGHRPHEGPGG--GISGGSGHRPHEGPGGGMGAGG- 827
               P +    GP G  G     G  G +  EGP G  G+ G  G     G  G  G  G 
Sbjct: 1011 PGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI 1070

Query: 828  ------------------GHRPHEGPGGSMG--------GSGGHRPHEG-PGHGGPHGHR 860
                              G+  + G  GS+G        G+ G +   G PG  G  G  
Sbjct: 1071 SSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPG-- 1128

Query: 861  PHDVPGHRGHDHRGPPPHEH-RGHDGPGHGGGGHRGHDG 898
                PG +G    GPP +    G  GP  GGGGH G  G
Sbjct: 1129 ---PPGPKGIS--GPPGNPGLPGEPGP-VGGGGHPGQPG 1161



 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 94/304 (30%), Positives = 108/304 (35%), Gaps = 78/304 (25%)

Query: 539  PGGSGGSPDGAG-GSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPS 597
            P G  G P   G G+  PP L  L G  G G  P  PG  G      L    G P  H  
Sbjct: 1177 PAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPG------LPGPKGEPGFHGF 1230

Query: 598  EELLKQPDYSDKIKQMLVPHGLLGP---GPIANGFPPGGPG-----GPKGMQHFPPG-PG 648
              +   P           P G  GP   GP  N  P G PG     GP+G    PPG PG
Sbjct: 1231 PGVQGPPG----------PPGSPGPALEGPKGNPGPQGPPGRPGLPGPEG----PPGLPG 1276

Query: 649  -GPMPGPHGGPGGPVGPRLLG-----PPPPPRG-----------GDPFWDG-PGDPMRGG 690
             G + G  G PG P  P L G      PP  +G           GDP   G PG P   G
Sbjct: 1277 NGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKG 1336

Query: 691  P--------------MRGGPGPG--PGPYHRGRGGRGGNEPP--PPPPPFRGARGGRSGG 732
            P              + G PGP   PGP  +    +G   PP  P  P  +G  G +   
Sbjct: 1337 PSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQ 1396

Query: 733  GPPNGRGGPGG-------GMVGGGGHRPHEGPGG-----GMGNSSGHRPHEGPGGGMGSG 780
            G P   G PG        G  G GG +   G  G     G+    G    +GP G  G+ 
Sbjct: 1397 GLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTS 1456

Query: 781  HRPH 784
               H
Sbjct: 1457 SVAH 1460


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.138    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,020,168
Number of Sequences: 37866
Number of extensions: 5389766
Number of successful extensions: 85682
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 681
Number of HSP's successfully gapped in prelim test: 1943
Number of HSP's that attempted gapping in prelim test: 24059
Number of HSP's gapped (non-prelim): 22649
length of query: 940
length of database: 18,247,518
effective HSP length: 112
effective length of query: 828
effective length of database: 14,006,526
effective search space: 11597403528
effective search space used: 11597403528
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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