Guide to the Human Genome
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Search of human proteins with 23238197

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23238197 tumor necrosis factor receptor superfamily, member
18 isoform 3 precursor [Homo sapiens]
         (234 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23238197 tumor necrosis factor receptor superfamily, member 1...   520   e-148
gi|4759246 tumor necrosis factor receptor superfamily, member 18...   512   e-145
gi|23238194 tumor necrosis factor receptor superfamily, member 1...   317   7e-87
gi|5730095 tumor necrosis factor receptor superfamily, member 9 ...    68   8e-12
gi|4507579 tumor necrosis factor receptor superfamily, member 4 ...    63   2e-10
gi|14790170 tumor necrosis factor receptor superfamily, member 6...    54   2e-07
gi|4507585 tumor necrosis factor receptor superfamily, member 6b...    54   2e-07
gi|4507565 tumor necrosis factor receptor superfamily, member 11...    52   3e-07
gi|148743793 osteoprotegerin precursor [Homo sapiens]                  50   1e-06
gi|7657039 tumor necrosis factor receptor superfamily, member 21...    50   1e-06
gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]             46   2e-05
gi|4507577 tumor necrosis factor receptor 2 precursor [Homo sapi...    45   7e-05
gi|4505039 lymphotoxin beta receptor [Homo sapiens]                    44   1e-04
gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]            39   0.004
gi|66346695 fibrillin 2 precursor [Homo sapiens]                       37   0.011
gi|239756792 PREDICTED: hypothetical protein [Homo sapiens]            37   0.015
gi|239751312 PREDICTED: hypothetical protein [Homo sapiens]            37   0.015
gi|239745809 PREDICTED: hypothetical protein [Homo sapiens]            37   0.015
gi|119703755 laminin, beta 2 precursor [Homo sapiens]                  36   0.033
gi|54400749 keratin associated protein 5-1 [Homo sapiens]              36   0.033
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s...    35   0.042
gi|60593038 keratin associated protein 5-4 [Homo sapiens]              35   0.042
gi|23200041 tumor necrosis factor receptor superfamily, member 1...    35   0.055
gi|29725609 epidermal growth factor receptor isoform a precursor...    34   0.095
gi|41327736 epidermal growth factor receptor isoform d precursor...    34   0.095
gi|41327734 epidermal growth factor receptor isoform c precursor...    34   0.095
gi|41327732 epidermal growth factor receptor isoform b precursor...    34   0.095
gi|65301164 very low density lipoprotein receptor isoform b [Hom...    34   0.12 
gi|65301167 very low density lipoprotein receptor isoform a [Hom...    34   0.12 
gi|11641231 ectodysplasin A receptor precursor [Homo sapiens]          34   0.12 

>gi|23238197 tumor necrosis factor receptor superfamily, member 18
           isoform 3 precursor [Homo sapiens]
          Length = 234

 Score =  520 bits (1340), Expect = e-148
 Identities = 234/234 (100%), Positives = 234/234 (100%)

Query: 1   MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRD 60
           MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRD
Sbjct: 1   MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRD 60

Query: 61  YPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTF 120
           YPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTF
Sbjct: 61  YPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTF 120

Query: 121 SGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVPGSPPAEPLGWLTVVLLAVAACVLLL 180
           SGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVPGSPPAEPLGWLTVVLLAVAACVLLL
Sbjct: 121 SGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVPGSPPAEPLGWLTVVLLAVAACVLLL 180

Query: 181 TSAQLGLHIWQLRKTQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLWV 234
           TSAQLGLHIWQLRKTQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLWV
Sbjct: 181 TSAQLGLHIWQLRKTQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLWV 234


>gi|4759246 tumor necrosis factor receptor superfamily, member 18
           isoform 1 precursor [Homo sapiens]
          Length = 241

 Score =  512 bits (1318), Expect = e-145
 Identities = 233/241 (96%), Positives = 234/241 (97%), Gaps = 7/241 (2%)

Query: 1   MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRD 60
           MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRD
Sbjct: 1   MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRD 60

Query: 61  YPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTF 120
           YPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTF
Sbjct: 61  YPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTF 120

Query: 121 SGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVPGSPPAEPLGWLTVVLLAVAACVLLL 180
           SGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVPGSPPAEPLGWLTVVLLAVAACVLLL
Sbjct: 121 SGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVPGSPPAEPLGWLTVVLLAVAACVLLL 180

Query: 181 TSAQLGLHIWQL-------RKTQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLW 233
           TSAQLGLHIWQL       R+TQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLW
Sbjct: 181 TSAQLGLHIWQLRSQCMWPRETQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLW 240

Query: 234 V 234
           V
Sbjct: 241 V 241


>gi|23238194 tumor necrosis factor receptor superfamily, member 18
           isoform 2 precursor [Homo sapiens]
          Length = 255

 Score =  317 bits (811), Expect = 7e-87
 Identities = 134/134 (100%), Positives = 134/134 (100%)

Query: 1   MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRD 60
           MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRD
Sbjct: 1   MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRD 60

Query: 61  YPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTF 120
           YPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTF
Sbjct: 61  YPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTF 120

Query: 121 SGGHEGHCKPWTDC 134
           SGGHEGHCKPWTDC
Sbjct: 121 SGGHEGHCKPWTDC 134


>gi|5730095 tumor necrosis factor receptor superfamily, member 9
           precursor [Homo sapiens]
          Length = 255

 Score = 67.8 bits (164), Expect = 8e-12
 Identities = 61/199 (30%), Positives = 81/199 (40%), Gaps = 41/199 (20%)

Query: 54  TTRCCRDYPG-----EECCSEWDCMC-VQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFS 107
           T   CR   G     +EC S  +  C   P FHC    C+ C    C  GQ +  +G   
Sbjct: 61  TCDICRQCKGVFRTRKECSSTSNAECDCTPGFHCLGAGCSMCEQD-CKQGQELTKKG--- 116

Query: 108 FGFQCIDCASGTFSGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVPG----------- 156
               C DC  GTF+    G C+PWT+C+  G   +  G K  + VC P            
Sbjct: 117 ----CKDCCFGTFNDQKRGICRPWTNCSLDGKSVLVNGTKERDVVCGPSPADLSPGASSV 172

Query: 157 SPPA---EPLGWLTVV--LLAVAACVLLLTSAQLGLH---IWQLRKTQLLLEVPP----- 203
           +PPA   EP     ++   LA+ +  LL     L L    + + RK  L +   P     
Sbjct: 173 TPPAPAREPGHSPQIISFFLALTSTALLFLLFFLTLRFSVVKRGRKKLLYIFKQPFMRPV 232

Query: 204 ---STEDARSCQFPEEERG 219
                ED  SC+FPEEE G
Sbjct: 233 QTTQEEDGCSCRFPEEEEG 251


>gi|4507579 tumor necrosis factor receptor superfamily, member 4
           precursor [Homo sapiens]
          Length = 277

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 40/125 (32%), Positives = 50/125 (40%), Gaps = 6/125 (4%)

Query: 42  GTGTDARCCRVHTTRCCRDYPG--EECCSEWDCM-CVQPEFHCGDP---CCTTCRHHPCP 95
           G G  +RC R   T C    PG   +  S   C  C       G      CT  +   C 
Sbjct: 49  GNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGSERKQLCTATQDTVCR 108

Query: 96  PGQGVQSQGKFSFGFQCIDCASGTFSGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVP 155
              G Q    +  G  C  C  G FS G    CKPWT+CT  G  T+ P + + +A+C  
Sbjct: 109 CRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKPWTNCTLAGKHTLQPASNSSDAICED 168

Query: 156 GSPPA 160
             PPA
Sbjct: 169 RDPPA 173



 Score = 32.7 bits (73), Expect = 0.28
 Identities = 20/62 (32%), Positives = 25/62 (40%), Gaps = 6/62 (9%)

Query: 74  CVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGH-CKPWT 132
           CV   +   D CC     H C PG G+ S+   S    C  C  G ++       CKP T
Sbjct: 31  CVGDTYPSNDRCC-----HECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCT 85

Query: 133 DC 134
            C
Sbjct: 86  WC 87


>gi|14790170 tumor necrosis factor receptor superfamily, member 6b
           [Homo sapiens]
          Length = 300

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 34/110 (30%), Positives = 42/110 (38%), Gaps = 19/110 (17%)

Query: 46  DARCCRVHTTRCCRDYPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGK 105
           +AR C     R CR   G               F      C    H  CPPG GV + G 
Sbjct: 101 EARACHATHNRACRCRTG---------------FFAHAGFCL--EHASCPPGAGVIAPGT 143

Query: 106 FSFGFQCIDCASGTFSGGHEG--HCKPWTDCTQFGFLTVFPGNKTHNAVC 153
            S   QC  C  GTFS        C+P  +CT  G     PG+ +H+ +C
Sbjct: 144 PSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLC 193


>gi|4507585 tumor necrosis factor receptor superfamily, member 6b
           [Homo sapiens]
          Length = 300

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 34/110 (30%), Positives = 42/110 (38%), Gaps = 19/110 (17%)

Query: 46  DARCCRVHTTRCCRDYPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGK 105
           +AR C     R CR   G               F      C    H  CPPG GV + G 
Sbjct: 101 EARACHATHNRACRCRTG---------------FFAHAGFCL--EHASCPPGAGVIAPGT 143

Query: 106 FSFGFQCIDCASGTFSGGHEG--HCKPWTDCTQFGFLTVFPGNKTHNAVC 153
            S   QC  C  GTFS        C+P  +CT  G     PG+ +H+ +C
Sbjct: 144 PSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLC 193


>gi|4507565 tumor necrosis factor receptor superfamily, member 11a
           precursor [Homo sapiens]
          Length = 616

 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 36/123 (29%), Positives = 53/123 (43%), Gaps = 8/123 (6%)

Query: 72  CMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEG--HCK 129
           C C    +H    C    R+  C PG G Q   + +    C  C +G FS        C+
Sbjct: 112 CACTAG-YHWSQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCR 170

Query: 130 PWTDCTQFGFLTVFPGNKTHNAVCVPG----SPPAEPLGWLT-VVLLAVAACVLLLTSAQ 184
           PWT+CT  G      G +  +AVC        PP EP  +L  +++L + A V L+ +  
Sbjct: 171 PWTNCTFLGKRVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAII 230

Query: 185 LGL 187
            G+
Sbjct: 231 FGV 233


>gi|148743793 osteoprotegerin precursor [Homo sapiens]
          Length = 401

 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 2/77 (2%)

Query: 90  RHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSG--GHEGHCKPWTDCTQFGFLTVFPGNK 147
           +H  CPPG GV   G       C  C  G FS     +  C+  T+C+ FG L    GN 
Sbjct: 120 KHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNA 179

Query: 148 THNAVCVPGSPPAEPLG 164
           TH+ +C   S   +  G
Sbjct: 180 THDNICSGNSESTQKCG 196


>gi|7657039 tumor necrosis factor receptor superfamily, member 21
           precursor [Homo sapiens]
          Length = 655

 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 28/85 (32%), Positives = 37/85 (43%), Gaps = 5/85 (5%)

Query: 71  DCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEG--HC 128
           +C C    F     C     H  CP G GV+ +G  +   +C  CA GTFS        C
Sbjct: 130 ECTCPPGMFQSNATCAP---HTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKC 186

Query: 129 KPWTDCTQFGFLTVFPGNKTHNAVC 153
           K +TDC     + + PG K  + VC
Sbjct: 187 KAYTDCLSQNLVVIKPGTKETDNVC 211


>gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]
          Length = 277

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 36/130 (27%), Positives = 46/130 (35%), Gaps = 11/130 (8%)

Query: 34  CGPGRLLLGTGTDARCCRVHTTRCCRDYPG----EECCSEWDCMCVQPE-FHCGDPCCTT 88
           CG    L     +  C   H  + C    G    ++  SE D +C   E +HC    C +
Sbjct: 62  CGESEFLDTWNRETHC---HQHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCTSEACES 118

Query: 89  C-RHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGH--CKPWTDCTQFGFLTVFPG 145
           C  H  C PG GV+          C  C  G FS        C PWT C     +    G
Sbjct: 119 CVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHPWTSCETKDLVVQQAG 178

Query: 146 NKTHNAVCVP 155
               + VC P
Sbjct: 179 TNKTDVVCGP 188


>gi|4507577 tumor necrosis factor receptor 2 precursor [Homo
           sapiens]
          Length = 461

 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 33/113 (29%), Positives = 45/113 (39%), Gaps = 14/113 (12%)

Query: 55  TRCCRDYPGEECCSEWD---CMCVQPEFHCG----DPCCTTCRHHPCPPGQGVQSQGKFS 107
           +RC  D    + C+      C C +P ++C     + C        C PG GV   G  +
Sbjct: 98  SRCSSDQVETQACTREQNRICTC-RPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTET 156

Query: 108 FGFQCIDCASGTFSG--GHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVPGSP 158
               C  CA GTFS        C+P   C     +   PGN + +AVC   SP
Sbjct: 157 SDVVCKPCAPGTFSNTTSSTDICRPHQICN----VVAIPGNASMDAVCTSTSP 205


>gi|4505039 lymphotoxin beta receptor [Homo sapiens]
          Length = 435

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 37/143 (25%), Positives = 53/143 (37%), Gaps = 16/143 (11%)

Query: 34  CGPGRLLLGTGTDARCCRVHTTRCCRDYPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHP 93
           C P   ++G    A C     T+C R  PG  C + W   C   E               
Sbjct: 101 CRPCDPVMGLEEIAPCTSKRKTQC-RCQPGMFCAA-WALECTHCELLSD----------- 147

Query: 94  CPPGQGVQSQGKFSFGFQ-CIDCASGTF--SGGHEGHCKPWTDCTQFGFLTVFPGNKTHN 150
           CPPG   + + +   G   C+ C +G F  +      C+P T C   G +   PG    +
Sbjct: 148 CPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSSPSARCQPHTRCENQGLVEAAPGTAQSD 207

Query: 151 AVCVPGSPPAEPLGWLTVVLLAV 173
             C     P  P    T+++LAV
Sbjct: 208 TTCKNPLEPLPPEMSGTMLMLAV 230


>gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]
          Length = 203

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 31/107 (28%), Positives = 39/107 (36%), Gaps = 11/107 (10%)

Query: 34  CGPGRLLLGTGTDARCCRVHTTRCCRDYPG----EECCSEWDCMCVQPE-FHCGDPCCTT 88
           CG    L     +  C   H  + C    G    ++  SE D +C   E +HC    C +
Sbjct: 62  CGESEFLDTWNRETHC---HQHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCTSEACES 118

Query: 89  C-RHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEG--HCKPWT 132
           C  H  C PG GV+          C  C  G FS        C PWT
Sbjct: 119 CVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHPWT 165


>gi|66346695 fibrillin 2 precursor [Homo sapiens]
          Length = 2912

 Score = 37.4 bits (85), Expect = 0.011
 Identities = 27/87 (31%), Positives = 32/87 (36%), Gaps = 22/87 (25%)

Query: 34  CGPGRLLLGTGTDARCCRVHTTR-----------CCRDYPGEECCSEWDCMCVQPEFHCG 82
           C PG   L  G D R C     R           C R +PG    SE  C C  P++  G
Sbjct: 684 CPPG---LAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSE--CCCANPDYGFG 738

Query: 83  DPCCTTCRHHPCPPGQGVQSQGKFSFG 109
           +PC       PCP     +  G  S G
Sbjct: 739 EPC------QPCPAKNSAEFHGLCSSG 759



 Score = 27.7 bits (60), Expect = 8.9
 Identities = 26/92 (28%), Positives = 31/92 (33%), Gaps = 32/92 (34%)

Query: 34   CGPGRLLLGTGTDARCCRVHTTRCCRDYPGEECCSEWD---CMCVQPEFHCGDPCC---- 86
            C  G  L GTG           R C D   E+C  +WD   C+   P     D CC    
Sbjct: 982  CPEGLTLDGTG-----------RVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVG 1030

Query: 87   ----TTCRHHP----------CPPGQGVQSQG 104
                T C   P          CP G G  ++G
Sbjct: 1031 AAWGTECEECPKPGTKEYETLCPRGAGFANRG 1062


>gi|239756792 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 188

 Score = 37.0 bits (84), Expect = 0.015
 Identities = 20/53 (37%), Positives = 24/53 (45%), Gaps = 7/53 (13%)

Query: 47  ARCCRVH--TTRCCRDYP-GEECCSEWDC--MCVQPEFHCGDPCCTTCRHHPC 94
           A CC+    +T CC+    G  CC +  C   C QP   CG  CC  C H  C
Sbjct: 73  ASCCQPSCCSTPCCQPTCCGSSCCGQTSCGSSCCQPI--CGSSCCQPCCHPTC 123



 Score = 28.1 bits (61), Expect = 6.8
 Identities = 23/76 (30%), Positives = 27/76 (35%), Gaps = 10/76 (13%)

Query: 49  CCRVHTTRCCRDYPGEECCSEWDC--MCVQPEFHCGDPCC-TTCRHHPC--PPGQGVQSQ 103
           CC      CC+      CC    C   C QP   C   CC  +C   PC  P   G    
Sbjct: 42  CC---VPSCCQPCCHPTCCQNTCCRTTCCQPT--CVASCCQPSCCSTPCCQPTCCGSSCC 96

Query: 104 GKFSFGFQCIDCASGT 119
           G+ S G  C     G+
Sbjct: 97  GQTSCGSSCCQPICGS 112


>gi|239751312 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 188

 Score = 37.0 bits (84), Expect = 0.015
 Identities = 20/53 (37%), Positives = 24/53 (45%), Gaps = 7/53 (13%)

Query: 47  ARCCRVH--TTRCCRDYP-GEECCSEWDC--MCVQPEFHCGDPCCTTCRHHPC 94
           A CC+    +T CC+    G  CC +  C   C QP   CG  CC  C H  C
Sbjct: 73  ASCCQPSCCSTPCCQPTCCGSSCCGQTSCGSSCCQPI--CGSSCCQPCCHPTC 123



 Score = 28.1 bits (61), Expect = 6.8
 Identities = 23/76 (30%), Positives = 27/76 (35%), Gaps = 10/76 (13%)

Query: 49  CCRVHTTRCCRDYPGEECCSEWDC--MCVQPEFHCGDPCC-TTCRHHPC--PPGQGVQSQ 103
           CC      CC+      CC    C   C QP   C   CC  +C   PC  P   G    
Sbjct: 42  CC---VPSCCQPCCHPTCCQNTCCRTTCCQPT--CVASCCQPSCCSTPCCQPTCCGSSCC 96

Query: 104 GKFSFGFQCIDCASGT 119
           G+ S G  C     G+
Sbjct: 97  GQTSCGSSCCQPICGS 112


>gi|239745809 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 188

 Score = 37.0 bits (84), Expect = 0.015
 Identities = 20/53 (37%), Positives = 24/53 (45%), Gaps = 7/53 (13%)

Query: 47  ARCCRVH--TTRCCRDYP-GEECCSEWDC--MCVQPEFHCGDPCCTTCRHHPC 94
           A CC+    +T CC+    G  CC +  C   C QP   CG  CC  C H  C
Sbjct: 73  ASCCQPSCCSTPCCQPTCCGSSCCGQTSCGSSCCQPI--CGSSCCQPCCHPTC 123



 Score = 28.1 bits (61), Expect = 6.8
 Identities = 23/76 (30%), Positives = 27/76 (35%), Gaps = 10/76 (13%)

Query: 49  CCRVHTTRCCRDYPGEECCSEWDC--MCVQPEFHCGDPCC-TTCRHHPC--PPGQGVQSQ 103
           CC      CC+      CC    C   C QP   C   CC  +C   PC  P   G    
Sbjct: 42  CC---VPSCCQPCCHPTCCQNTCCRTTCCQPT--CVASCCQPSCCSTPCCQPTCCGSSCC 96

Query: 104 GKFSFGFQCIDCASGT 119
           G+ S G  C     G+
Sbjct: 97  GQTSCGSSCCQPICGS 112


>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
          Length = 1798

 Score = 35.8 bits (81), Expect = 0.033
 Identities = 32/94 (34%), Positives = 37/94 (39%), Gaps = 29/94 (30%)

Query: 50  CRVHTTRC--CRDYPGEECCSEWDCMCVQPEFHCGDPCCT---TCRHHPCPPGQGVQ--- 101
           C  HT  C  CRD+ G E C      C+   FH GDP       CR  PCP G G Q   
Sbjct: 886 CNTHTGACLGCRDHTGGEHCER----CIAG-FH-GDPRLPYGGQCRPCPCPEGPGSQRHF 939

Query: 102 ----SQGKFS-----------FGFQCIDCASGTF 120
                Q ++S            G +C  CA G F
Sbjct: 940 ATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHF 973


>gi|54400749 keratin associated protein 5-1 [Homo sapiens]
          Length = 278

 Score = 35.8 bits (81), Expect = 0.033
 Identities = 27/95 (28%), Positives = 32/95 (33%), Gaps = 5/95 (5%)

Query: 5   GAMGAFRALCGLALLCALSLGQ--RPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRDYP 62
           G+ G  +  CG    C    G      GG G G G    G G    CC   +   C    
Sbjct: 168 GSCGGSKGGCGSCGGCKGGCGSCGGSKGGCGSGCGGCGSGCGVPVCCCSCSSCGSCAGSK 227

Query: 63  GEECCSEWDCMCVQP---EFHCGDPCCTTCRHHPC 94
           G    S   C C +P      CG  CC +    PC
Sbjct: 228 GGCGSSCSQCSCCKPCCCSSGCGSSCCQSSCCKPC 262



 Score = 31.2 bits (69), Expect = 0.80
 Identities = 34/118 (28%), Positives = 39/118 (33%), Gaps = 25/118 (21%)

Query: 14  CGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRDYPGEECCSEWDCM 73
           CG +  C  S G   +G  GCG G    G+G     C    + CC       CC      
Sbjct: 4   CGCSGGCGSSCGGCGSGCGGCGSGCGGCGSG-----CGGSGSSCCVPV----CC------ 48

Query: 74  CVQPEFHCGDPCC--TTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFS-GGHEGHC 128
                  C   CC   TC    C  G    S G       C  C  G  S GG +G C
Sbjct: 49  -------CKPVCCRVPTCSCSSCGKGGCGSSGGSKGGCGSCGGCKGGCGSCGGSKGGC 99



 Score = 30.4 bits (67), Expect = 1.4
 Identities = 20/79 (25%), Positives = 27/79 (34%), Gaps = 11/79 (13%)

Query: 14  CGLALLCAL--SLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRDYPGEECCSEWD 71
           CG+ + C    S G       GCG       + +   CC+     CC    G  CC    
Sbjct: 208 CGVPVCCCSCSSCGSCAGSKGGCG------SSCSQCSCCK---PCCCSSGCGSSCCQSSC 258

Query: 72  CMCVQPEFHCGDPCCTTCR 90
           C     +  C  P C  C+
Sbjct: 259 CKPCCSQSSCCVPVCCQCK 277


>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
           sapiens]
          Length = 1037

 Score = 35.4 bits (80), Expect = 0.042
 Identities = 53/210 (25%), Positives = 73/210 (34%), Gaps = 32/210 (15%)

Query: 20  CALSLGQR-PTGGPGCGPGRLLLGTGTDARC--CRVHTTRCCRDYPGE-ECCSEW---DC 72
           C  + G R P+    C PGR         RC  C+      C    G   C + W   DC
Sbjct: 595 CVCAPGFRGPSCQRSCQPGRY------GKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDC 648

Query: 73  MCVQPEFHCGDPCCTTCRHH---PCPPGQGVQSQGKFSFGFQCID-CASGTFSG--GHEG 126
               P  H G+ C  TC+ H    C P  G         G  C++ C  GTF        
Sbjct: 649 SQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPC 708

Query: 127 HCKPWTDC-TQFGFLTVFPGNKTHNAVC----------VPGSPPAEPLGWLTVVLLAVAA 175
            C P   C  + G     PG+    A C          +P +P A       + +  + +
Sbjct: 709 QCGPGEKCHPETGACVCPPGHS--GAPCRIGIQEPFTVMPTTPVAYNSLGAVIGIAVLGS 766

Query: 176 CVLLLTSAQLGLHIWQLRKTQLLLEVPPST 205
            V+ L +  +G   WQ  K    L V  S+
Sbjct: 767 LVVALVALFIGYRHWQKGKEHHHLAVAYSS 796


>gi|60593038 keratin associated protein 5-4 [Homo sapiens]
          Length = 288

 Score = 35.4 bits (80), Expect = 0.042
 Identities = 22/90 (24%), Positives = 32/90 (35%), Gaps = 9/90 (10%)

Query: 5   GAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRDYPGE 64
           G+ G  +  C     C+   G        C P      +G  + CC+   + CC+ Y   
Sbjct: 192 GSCGCSQCSCCKPCCCSSGCGSSCCQSSCCKP--CCSSSGCGSSCCQ---SSCCKPY--- 243

Query: 65  ECCSEWDCMCVQPEFHCGDPCCTTCRHHPC 94
            CC    C        CG  CC +   +PC
Sbjct: 244 -CCQSSCCKPCCSSSGCGSSCCQSSCCNPC 272



 Score = 28.5 bits (62), Expect = 5.2
 Identities = 30/115 (26%), Positives = 38/115 (33%), Gaps = 17/115 (14%)

Query: 14  CGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRDYPGEECCSEWDCM 73
           CG +  C    G   +G  GCG G    G G+    C      C        CC +  C 
Sbjct: 4   CGCSGGCGSGCGGCGSGCGGCGSG--CGGCGSGCGGCGSGCGGCGSSCCVPICCCKPVCC 61

Query: 74  CVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGHC 128
           CV        P C+      C   +G       S G  C+ C      GG +G C
Sbjct: 62  CV--------PACSCSSCGSCGGSKGGYGSCGGSKG-GCVSC------GGSKGGC 101


>gi|23200041 tumor necrosis factor receptor superfamily, member 14
           precursor [Homo sapiens]
          Length = 283

 Score = 35.0 bits (79), Expect = 0.055
 Identities = 30/110 (27%), Positives = 39/110 (35%), Gaps = 9/110 (8%)

Query: 34  CGPGRLLLGTGTDARCCRVHTTRCCRDYPGEECCSEWD---CMCVQPEFHC----GDPCC 86
           C PG  +      ++C +               CS  +   C C  P   C    GD C 
Sbjct: 78  CPPGTYIAHLNGLSKCLQCQMCDPAMGLRASRNCSRTENAVCGC-SPGHFCIVQDGDHCA 136

Query: 87  TTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFS-GGHEGHCKPWTDCT 135
               +    PGQ VQ  G  S    C +C  GTFS  G    C+  T C+
Sbjct: 137 ACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFSPNGTLEECQHQTKCS 186



 Score = 29.3 bits (64), Expect = 3.0
 Identities = 20/61 (32%), Positives = 25/61 (40%), Gaps = 12/61 (19%)

Query: 60  DYP-GEECCSEWDCMCVQPEFH----CGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCID 114
           +YP G ECC +       P +     CG+   T C   PCPPG  +      S   QC  
Sbjct: 46  EYPVGSECCPK-----CSPGYRVKEACGELTGTVCE--PCPPGTYIAHLNGLSKCLQCQM 98

Query: 115 C 115
           C
Sbjct: 99  C 99


>gi|29725609 epidermal growth factor receptor isoform a precursor
           [Homo sapiens]
          Length = 1210

 Score = 34.3 bits (77), Expect = 0.095
 Identities = 22/96 (22%), Positives = 35/96 (36%), Gaps = 5/96 (5%)

Query: 38  RLLLGTGTDARCCRVHTTRCCRDYPGEECCS--EWDCMCVQP---EFHCGDPCCTTCRHH 92
           +++       RC     + CC +     C    E DC+  +    E  C D C     ++
Sbjct: 212 KIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYN 271

Query: 93  PCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGHC 128
           P      V  +GK+SFG  C+      +     G C
Sbjct: 272 PTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSC 307


>gi|41327736 epidermal growth factor receptor isoform d precursor
           [Homo sapiens]
          Length = 705

 Score = 34.3 bits (77), Expect = 0.095
 Identities = 22/96 (22%), Positives = 35/96 (36%), Gaps = 5/96 (5%)

Query: 38  RLLLGTGTDARCCRVHTTRCCRDYPGEECCS--EWDCMCVQP---EFHCGDPCCTTCRHH 92
           +++       RC     + CC +     C    E DC+  +    E  C D C     ++
Sbjct: 212 KIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYN 271

Query: 93  PCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGHC 128
           P      V  +GK+SFG  C+      +     G C
Sbjct: 272 PTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSC 307


>gi|41327734 epidermal growth factor receptor isoform c precursor
           [Homo sapiens]
          Length = 405

 Score = 34.3 bits (77), Expect = 0.095
 Identities = 22/96 (22%), Positives = 35/96 (36%), Gaps = 5/96 (5%)

Query: 38  RLLLGTGTDARCCRVHTTRCCRDYPGEECCS--EWDCMCVQP---EFHCGDPCCTTCRHH 92
           +++       RC     + CC +     C    E DC+  +    E  C D C     ++
Sbjct: 212 KIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYN 271

Query: 93  PCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGHC 128
           P      V  +GK+SFG  C+      +     G C
Sbjct: 272 PTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSC 307


>gi|41327732 epidermal growth factor receptor isoform b precursor
           [Homo sapiens]
          Length = 628

 Score = 34.3 bits (77), Expect = 0.095
 Identities = 22/96 (22%), Positives = 35/96 (36%), Gaps = 5/96 (5%)

Query: 38  RLLLGTGTDARCCRVHTTRCCRDYPGEECCS--EWDCMCVQP---EFHCGDPCCTTCRHH 92
           +++       RC     + CC +     C    E DC+  +    E  C D C     ++
Sbjct: 212 KIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYN 271

Query: 93  PCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGHC 128
           P      V  +GK+SFG  C+      +     G C
Sbjct: 272 PTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSC 307


>gi|65301164 very low density lipoprotein receptor isoform b [Homo
           sapiens]
          Length = 845

 Score = 33.9 bits (76), Expect = 0.12
 Identities = 32/109 (29%), Positives = 38/109 (34%), Gaps = 11/109 (10%)

Query: 30  GGPGCGPGRLLLGTGTDARCCRVHTTRCCRDYP-----GEECCSEWDCMCVQPEFHCGDP 84
           G P C  G          R CR+H   C             C  E DC   + E +CG+ 
Sbjct: 93  GDPDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGENDCDSGEDEENCGNI 152

Query: 85  CCT----TCRHHPCPPGQGV-QSQGKFSFGFQCIDCASGTFSGGHEGHC 128
            C+    TC    C     V   Q   S G   +DCA  T  G HE  C
Sbjct: 153 TCSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPT-CGAHEFQC 200


>gi|65301167 very low density lipoprotein receptor isoform a [Homo
           sapiens]
          Length = 873

 Score = 33.9 bits (76), Expect = 0.12
 Identities = 32/109 (29%), Positives = 38/109 (34%), Gaps = 11/109 (10%)

Query: 30  GGPGCGPGRLLLGTGTDARCCRVHTTRCCRDYP-----GEECCSEWDCMCVQPEFHCGDP 84
           G P C  G          R CR+H   C             C  E DC   + E +CG+ 
Sbjct: 93  GDPDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGENDCDSGEDEENCGNI 152

Query: 85  CCT----TCRHHPCPPGQGV-QSQGKFSFGFQCIDCASGTFSGGHEGHC 128
            C+    TC    C     V   Q   S G   +DCA  T  G HE  C
Sbjct: 153 TCSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPT-CGAHEFQC 200


>gi|11641231 ectodysplasin A receptor precursor [Homo sapiens]
          Length = 448

 Score = 33.9 bits (76), Expect = 0.12
 Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 7/79 (8%)

Query: 87  TTCRHHPCPP-GQGVQSQGKFSFG-----FQCIDCASGTFSGGHEGHCKPWTDCTQFGFL 140
           TT     CPP G G +      +G     + C+ C +  FS G    C+   DC  F   
Sbjct: 40  TTGLCQECPPCGPGEEPYLSCGYGTKDEDYGCVPCPAEKFSKGGYQICRRHKDCEGFFRA 99

Query: 141 TVF-PGNKTHNAVCVPGSP 158
           TV  PG+  ++A C P  P
Sbjct: 100 TVLTPGDMENDAECGPCLP 118


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.141    0.501 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,665,213
Number of Sequences: 37866
Number of extensions: 719708
Number of successful extensions: 3001
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 122
Number of HSP's that attempted gapping in prelim test: 2815
Number of HSP's gapped (non-prelim): 289
length of query: 234
length of database: 18,247,518
effective HSP length: 99
effective length of query: 135
effective length of database: 14,498,784
effective search space: 1957335840
effective search space used: 1957335840
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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