Guide to the Human Genome
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Name: EGFR Sequence: fasta or formatted (705aa) NCBI GI: 41327736
Description:

epidermal growth factor receptor isoform d precursor

Referenced in:

Epidermal Growth Factor
Retroviral Oncogene Homologs

Other entries for this name:
alt prot [1210aa] epidermal growth factor receptor isoform a precursor
alt prot [628aa] epidermal growth factor receptor isoform b precursor
alt prot [405aa] epidermal growth factor receptor isoform c precursor
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.0         42           2
 C cysteine            7.7         54           2
 D aspartate           4.1         29           1
 E glutamate           6.0         42           2
 F phenylalanine       3.0         21           1
 G glycine             7.9         56           2
 H histidine           3.0         21           1
 I isoleucine          5.1         36           2
 K lysine              5.2         37           2
 L leucine             8.9         63           2
 M methionine          1.7         12           1
 N asparagine          6.7         47           2
 P proline             5.0         35           2
 Q glutamine           4.0         28           2
 R arginine            4.3         30           1
 S serine              8.1         57           2
 T threonine           5.0         35           2
 V valine              5.0         35           2
 W tryptophan          1.3          9           1
 Y tyrosine            2.3         16           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   epidermal growth factor receptor isoform d precursor... 
EGFR                  0.888   epidermal growth factor receptor isoform a precursor...
EGFR                  0.888   epidermal growth factor receptor isoform b precursor...
EGFR                  0.558   epidermal growth factor receptor isoform c precursor...
ERBB4                 0.411   v-erb-a erythroblastic leukemia viral oncogene homo...
ERBB4                 0.411   v-erb-a erythroblastic leukemia viral oncogene homolo...
ERBB3                 0.384   erbB-3 isoform 1 precursor 
ERBB2                 0.377   erbB-2 isoform a 
ERBB2                 0.368   erbB-2 isoform b 
INSR                  0.073   insulin receptor isoform Short precursor 
INSR                  0.073   insulin receptor isoform Long precursor 
INSRR                 0.057   insulin receptor-related receptor precursor 
IGF1R                 0.056   insulin-like growth factor 1 receptor precursor [Homo...
ERBB3                 0.055   erbB-3 isoform s precursor 
PCSK6                 0.024   paired basic amino acid cleaving system 4 isoform h ...
PCSK6                 0.024   paired basic amino acid cleaving system 4 isoform g ...
PCSK6                 0.024   paired basic amino acid cleaving system 4 isoform a p...
PCSK6                 0.024   paired basic amino acid cleaving system 4 isoform b ...
LOC100292811          0.024   PREDICTED: similar to proprotein convertase subtili...
LOC100290671          0.023   PREDICTED: hypothetical protein XP_002347099 
LOC100289618          0.023   PREDICTED: hypothetical protein XP_002342982 
PCSK5                 0.020   proprotein convertase subtilisin/kexin type 5 prepro...
FRAS1                 0.020   Fraser syndrome 1 
MEGF10                0.014   multiple EGF-like-domains 10 
PEAR1                 0.012   platelet endothelial aggregation receptor 1 
ZNFX1                 0.010   zinc finger, NFX1-type containing 1 
LAMA5                 0.010   laminin alpha 5 
SCARF1                0.009   scavenger receptor class F, member 1 isoform 3 precu...
SCARF1                0.009   scavenger receptor class F, member 1 isoform 1 precu...
MEGF11                0.009   multiple EGF-like-domains 11 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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