Guide to the Human Genome
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Name: EGFR Sequence: fasta or formatted (405aa) NCBI GI: 41327734
Description:

epidermal growth factor receptor isoform c precursor

Referenced in:

Epidermal Growth Factor
Retroviral Oncogene Homologs

Other entries for this name:
alt prot [1210aa] epidermal growth factor receptor isoform a precursor
alt prot [628aa] epidermal growth factor receptor isoform b precursor
alt prot [705aa] epidermal growth factor receptor isoform d precursor
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.2         25           2
 C cysteine            7.2         29           2
 D aspartate           4.9         20           1
 E glutamate           5.9         24           2
 F phenylalanine       3.2         13           1
 G glycine             7.2         29           1
 H histidine           2.0          8           1
 I isoleucine          4.7         19           2
 K lysine              5.9         24           2
 L leucine             9.4         38           2
 M methionine          2.2          9           1
 N asparagine          6.7         27           2
 P proline             4.7         19           2
 Q glutamine           4.0         16           2
 R arginine            4.7         19           1
 S serine              7.2         29           2
 T threonine           5.4         22           2
 V valine              5.2         21           2
 W tryptophan          0.5          2           1
 Y tyrosine            3.0         12           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   epidermal growth factor receptor isoform c precursor... 
EGFR                  0.996   epidermal growth factor receptor isoform a precursor...
EGFR                  0.996   epidermal growth factor receptor isoform d precursor...
EGFR                  0.996   epidermal growth factor receptor isoform b precursor...
ERBB4                 0.442   v-erb-a erythroblastic leukemia viral oncogene homo...
ERBB4                 0.442   v-erb-a erythroblastic leukemia viral oncogene homolo...
ERBB2                 0.410   erbB-2 isoform a 
ERBB3                 0.396   erbB-3 isoform 1 precursor 
ERBB2                 0.395   erbB-2 isoform b 
INSR                  0.109   insulin receptor isoform Short precursor 
INSR                  0.109   insulin receptor isoform Long precursor 
ERBB3                 0.098   erbB-3 isoform s precursor 
IGF1R                 0.084   insulin-like growth factor 1 receptor precursor [Homo...
INSRR                 0.069   insulin receptor-related receptor precursor 
PCSK5                 0.036   proprotein convertase subtilisin/kexin type 5 prepro...
FRAS1                 0.034   Fraser syndrome 1 
LOC100292811          0.032   PREDICTED: similar to proprotein convertase subtili...
LOC100290671          0.032   PREDICTED: hypothetical protein XP_002347099 
LOC100289618          0.032   PREDICTED: hypothetical protein XP_002342982 
ZNFX1                 0.018   zinc finger, NFX1-type containing 1 
PCSK6                 0.018   paired basic amino acid cleaving system 4 isoform h ...
PCSK6                 0.018   paired basic amino acid cleaving system 4 isoform g ...
PCSK6                 0.018   paired basic amino acid cleaving system 4 isoform a p...
PCSK6                 0.018   paired basic amino acid cleaving system 4 isoform b ...
NELL1                 0.015   nel-like 1 isoform 2 precursor 
NELL1                 0.015   nel-like 1 isoform 1 precursor 
LRP2                  0.015   low density lipoprotein-related protein 2 
SCARF1                0.015   scavenger receptor class F, member 1 isoform 3 precu...
SCARF1                0.015   scavenger receptor class F, member 1 isoform 1 precu...
JAG2                  0.015   jagged 2 isoform b precursor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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