Search of human proteins with 23200041

Search of human proteins with 23200041

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23200041 tumor necrosis factor receptor superfamily, member
14 precursor [Homo sapiens]
         (283 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23200041 tumor necrosis factor receptor superfamily, member 1...   612   e-175
gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]            101   8e-22
gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]            99   5e-21
gi|4507577 tumor necrosis factor receptor 2 precursor [Homo sapi...    99   5e-21
gi|14790170 tumor necrosis factor receptor superfamily, member 6...    95   8e-20
gi|4507585 tumor necrosis factor receptor superfamily, member 6b...    95   8e-20
gi|4505039 lymphotoxin beta receptor [Homo sapiens]                    89   4e-18
gi|148743793 osteoprotegerin precursor [Homo sapiens]                  80   2e-15
gi|4507565 tumor necrosis factor receptor superfamily, member 11...    79   6e-15
gi|7657039 tumor necrosis factor receptor superfamily, member 21...    77   1e-14
gi|4507569 tumor necrosis factor receptor superfamily, member 25...    73   2e-13
gi|23200023 tumor necrosis factor receptor superfamily, member 2...    73   3e-13
gi|4505393 nerve growth factor receptor precursor [Homo sapiens]       72   5e-13
gi|4507579 tumor necrosis factor receptor superfamily, member 4 ...    70   2e-12
gi|4507583 tumor necrosis factor receptor superfamily, member 6 ...    68   8e-12
gi|23200021 tumor necrosis factor receptor superfamily, member 2...    68   1e-11
gi|23510423 tumor necrosis factor receptor superfamily, member 6...    67   2e-11
gi|89142745 tumor necrosis factor receptor superfamily, member 2...    67   2e-11
gi|23510421 tumor necrosis factor receptor superfamily, member 6...    65   5e-11
gi|68348711 tumor necrosis factor receptor superfamily, member 8...    62   6e-10
gi|5730095 tumor necrosis factor receptor superfamily, member 9 ...    59   4e-09
gi|22547108 tumor necrosis factor receptor superfamily, member 1...    56   4e-08
gi|4507587 tumor necrosis factor receptor superfamily, member 7 ...    54   2e-07
gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapi...    53   3e-07
gi|224494019 tumor necrosis factor receptor superfamily, member ...    50   2e-06
gi|224494026 tumor necrosis factor receptor superfamily, member ...    49   6e-06
gi|11140823 X-linked ectodysplasin receptor [Homo sapiens]             48   1e-05
gi|110611156 laminin, gamma 3 precursor [Homo sapiens]                 44   1e-04
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]                44   1e-04
gi|23200025 tumor necrosis factor receptor superfamily, member 2...    42   5e-04

>gi|23200041 tumor necrosis factor receptor superfamily, member 14
           precursor [Homo sapiens]
          Length = 283

 Score =  612 bits (1578), Expect = e-175
 Identities = 283/283 (100%), Positives = 283/283 (100%)

Query: 1   MEPPGDWGPPPWRSTPKTDVLRLVLYLTFLGAPCYAPALPSCKEDEYPVGSECCPKCSPG 60
           MEPPGDWGPPPWRSTPKTDVLRLVLYLTFLGAPCYAPALPSCKEDEYPVGSECCPKCSPG
Sbjct: 1   MEPPGDWGPPPWRSTPKTDVLRLVLYLTFLGAPCYAPALPSCKEDEYPVGSECCPKCSPG 60

Query: 61  YRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRASRNCSRTENAVCG 120
           YRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRASRNCSRTENAVCG
Sbjct: 61  YRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRASRNCSRTENAVCG 120

Query: 121 CSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFSPNGTLEECQ 180
           CSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFSPNGTLEECQ
Sbjct: 121 CSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFSPNGTLEECQ 180

Query: 181 HQTKCSWLVTKAGAGTSSSHWVWWFLSGSLVIVIVCSTVGLIICVKRRKPRGDVVKVIVS 240
           HQTKCSWLVTKAGAGTSSSHWVWWFLSGSLVIVIVCSTVGLIICVKRRKPRGDVVKVIVS
Sbjct: 181 HQTKCSWLVTKAGAGTSSSHWVWWFLSGSLVIVIVCSTVGLIICVKRRKPRGDVVKVIVS 240

Query: 241 VQRKRQEAEGEATVIEALQAPPDVTTVAVEETIPSFTGRSPNH 283
           VQRKRQEAEGEATVIEALQAPPDVTTVAVEETIPSFTGRSPNH
Sbjct: 241 VQRKRQEAEGEATVIEALQAPPDVTTVAVEETIPSFTGRSPNH 283


>gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]
          Length = 277

 Score =  101 bits (251), Expect = 8e-22
 Identities = 48/146 (32%), Positives = 74/146 (50%), Gaps = 4/146 (2%)

Query: 41  SCKEDEYPVGSECCPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCD 100
           +C+E +Y + S+CC  C PG ++   C E T T C PC    ++   N  + C Q + CD
Sbjct: 25  ACREKQYLINSQCCSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCD 84

Query: 101 PAMGLRASRNCSRTENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDT 160
           P +GLR  +  +   + +C C  G  C     + C +C  + + SPG  V++  T   DT
Sbjct: 85  PNLGLRVQQKGTSETDTICTCEEGWHC---TSEACESCVLHRSCSPGFGVKQIATGVSDT 141

Query: 161 LCQNCPPGTFS-PNGTLEECQHQTKC 185
           +C+ CP G FS  +   E+C   T C
Sbjct: 142 ICEPCPVGFFSNVSSAFEKCHPWTSC 167



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 7/83 (8%)

Query: 44  EDEYPVGSECCPKC------SPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQ 97
           E+ +   SE C  C      SPG+ VK+    ++ T+CEPCP G +    +   KC    
Sbjct: 106 EEGWHCTSEACESCVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHPWT 165

Query: 98  MCDPAMGLRASRNCSRTENAVCG 120
            C+    +      ++T+  VCG
Sbjct: 166 SCETKDLVVQQAGTNKTD-VVCG 187


>gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]
          Length = 203

 Score = 98.6 bits (244), Expect = 5e-21
 Identities = 47/145 (32%), Positives = 74/145 (51%), Gaps = 4/145 (2%)

Query: 41  SCKEDEYPVGSECCPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCD 100
           +C+E +Y + S+CC  C PG ++   C E T T C PC    ++   N  + C Q + CD
Sbjct: 25  ACREKQYLINSQCCSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCD 84

Query: 101 PAMGLRASRNCSRTENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDT 160
           P +GLR  +  +   + +C C  G  C     + C +C  + + SPG  V++  T   DT
Sbjct: 85  PNLGLRVQQKGTSETDTICTCEEGWHC---TSEACESCVLHRSCSPGFGVKQIATGVSDT 141

Query: 161 LCQNCPPGTFS-PNGTLEECQHQTK 184
           +C+ CP G FS  +   E+C   T+
Sbjct: 142 ICEPCPVGFFSNVSSAFEKCHPWTR 166


>gi|4507577 tumor necrosis factor receptor 2 precursor [Homo
           sapiens]
          Length = 461

 Score = 98.6 bits (244), Expect = 5e-21
 Identities = 53/146 (36%), Positives = 70/146 (47%), Gaps = 16/146 (10%)

Query: 35  YAPALPS-CKEDEY--PVGSECCPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLS 91
           YAP   S C+  EY       CC KCSPG   K  C + + TVC+ C   TY    N + 
Sbjct: 32  YAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVP 91

Query: 92  KCLQCQMCDPAMGLRASRN------CSRTENAVCGCSPGHFCIVQDGDHCAACRAYATSS 145
           +CL C       G R S +      C+R +N +C C PG +C +   + C  C       
Sbjct: 92  ECLSC-------GSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCR 144

Query: 146 PGQRVQKGGTESQDTLCQNCPPGTFS 171
           PG  V + GTE+ D +C+ C PGTFS
Sbjct: 145 PGFGVARPGTETSDVVCKPCAPGTFS 170



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 2/50 (4%)

Query: 53  CCP--KCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCD 100
           C P  KC PG+ V     E +  VC+PC PGT+    +    C   Q+C+
Sbjct: 137 CAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICN 186


>gi|14790170 tumor necrosis factor receptor superfamily, member 6b
           [Homo sapiens]
          Length = 300

 Score = 94.7 bits (234), Expect = 8e-20
 Identities = 55/149 (36%), Positives = 68/149 (45%), Gaps = 10/149 (6%)

Query: 54  CPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQ-MCDPAMGLRASRNCS 112
           C +C PG  V+  C   + T C PCPP  Y    N L +C  C  +C        +R C 
Sbjct: 49  CAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGERE--EEARACH 106

Query: 113 RTENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFS- 171
            T N  C C  G F       H   C  +A+  PG  V   GT SQ+T CQ CPPGTFS 
Sbjct: 107 ATHNRACRCRTGFFA------HAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSA 160

Query: 172 PNGTLEECQHQTKCSWLVTKAGAGTSSSH 200
            + + E+CQ    C+ L        SSSH
Sbjct: 161 SSSSSEQCQPHRNCTALGLALNVPGSSSH 189


>gi|4507585 tumor necrosis factor receptor superfamily, member 6b
           [Homo sapiens]
          Length = 300

 Score = 94.7 bits (234), Expect = 8e-20
 Identities = 55/149 (36%), Positives = 68/149 (45%), Gaps = 10/149 (6%)

Query: 54  CPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQ-MCDPAMGLRASRNCS 112
           C +C PG  V+  C   + T C PCPP  Y    N L +C  C  +C        +R C 
Sbjct: 49  CAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGERE--EEARACH 106

Query: 113 RTENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFS- 171
            T N  C C  G F       H   C  +A+  PG  V   GT SQ+T CQ CPPGTFS 
Sbjct: 107 ATHNRACRCRTGFFA------HAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSA 160

Query: 172 PNGTLEECQHQTKCSWLVTKAGAGTSSSH 200
            + + E+CQ    C+ L        SSSH
Sbjct: 161 SSSSSEQCQPHRNCTALGLALNVPGSSSH 189


>gi|4505039 lymphotoxin beta receptor [Homo sapiens]
          Length = 435

 Score = 89.0 bits (219), Expect = 4e-18
 Identities = 64/251 (25%), Positives = 102/251 (40%), Gaps = 25/251 (9%)

Query: 33  PCYAPALPSCKEDEY----PVGSECCPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLN 88
           P YA    +C++ E     P    CC +C PG  V   C  +  TVC  C   +Y  H N
Sbjct: 34  PPYASENQTCRDQEKEYYEPQHRICCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWN 93

Query: 89  GLSKCLQCQMCDPAMGLRASRNCSRTENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQ 148
            L+ C  C+ CDP MGL     C+      C C PG FC       C  C   +   PG 
Sbjct: 94  YLTICQLCRPCDPVMGLEEIAPCTSKRKTQCRCQPGMFCAAW-ALECTHCELLSDCPPGT 152

Query: 149 RVQ-KGGTESQDTLCQNCPPGTF-SPNGTLEECQHQTKC-SWLVTKAGAGTSSSHWVWW- 204
             + K      +  C  C  G F + +     CQ  T+C +  + +A  GT+ S      
Sbjct: 153 EAELKDEVGKGNNHCVPCKAGHFQNTSSPSARCQPHTRCENQGLVEAAPGTAQSDTTCKN 212

Query: 205 -------FLSGSLVIVIVCSTVGLII-------CVKRRKPRGDVVKVIVSVQRKRQEAEG 250
                   +SG+++++ V   +   +       C+ +  P   + + + S+ ++R + EG
Sbjct: 213 PLEPLPPEMSGTMLMLAVLLPLAFFLLLATVFSCIWKSHP--SLCRKLGSLLKRRPQGEG 270

Query: 251 EATVIEALQAP 261
              V  + + P
Sbjct: 271 PNPVAGSWEPP 281


>gi|148743793 osteoprotegerin precursor [Homo sapiens]
          Length = 401

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 47/148 (31%), Positives = 70/148 (47%), Gaps = 13/148 (8%)

Query: 54  CPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQ-MCDPAMGLRASRNCS 112
           C KC PG  +K+ C     TVC PCP   Y    +   +CL C  +C     ++  + C+
Sbjct: 41  CDKCPPGTYLKQHCTAKWKTVCAPCPDHYYTDSWHTSDECLYCSPVCKELQYVK--QECN 98

Query: 113 RTENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFS- 171
           RT N VC C  G +  ++       C  + +  PG  V + GT  ++T+C+ CP G FS 
Sbjct: 99  RTHNRVCECKEGRYLEIE------FCLKHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSN 152

Query: 172 PNGTLEECQHQTKCS---WLVTKAGAGT 196
              +   C+  T CS    L+T+ G  T
Sbjct: 153 ETSSKAPCRKHTNCSVFGLLLTQKGNAT 180



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 31/111 (27%), Positives = 44/111 (39%), Gaps = 9/111 (8%)

Query: 53  CCPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRASRNCS 112
           C P C     VK+ C      VCE C  G Y+     +  CL+ + C P  G+  +    
Sbjct: 83  CSPVCKELQYVKQECNRTHNRVCE-CKEGRYLE----IEFCLKHRSCPPGFGVVQAGTPE 137

Query: 113 RTENAVCGCSPGHFCIVQDGDHCAACRAYATSSP-GQRVQKGGTESQDTLC 162
           R  N VC   P  F    +    A CR +   S  G  + + G  + D +C
Sbjct: 138 R--NTVCKRCPDGF-FSNETSSKAPCRKHTNCSVFGLLLTQKGNATHDNIC 185


>gi|4507565 tumor necrosis factor receptor superfamily, member 11a
           precursor [Homo sapiens]
          Length = 616

 Score = 78.6 bits (192), Expect = 6e-15
 Identities = 46/152 (30%), Positives = 66/152 (43%), Gaps = 5/152 (3%)

Query: 38  ALPSCKEDEYPVGSECCPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQ 97
           A P   E  Y     CC KC PG  +   C   + +VC PC P  Y+   N   KCL  +
Sbjct: 31  APPCTSEKHYEHLGRCCNKCEPGKYMSSKCTTTSDSVCLPCGPDEYLDSWNEEDKCLLHK 90

Query: 98  MCDPAMGLRASRNCSRTENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTES 157
           +CD    L A    + T    C C+ G+         C  CR     +PG   Q     +
Sbjct: 91  VCDTGKALVAVVAGNSTTPRRCACTAGYHW----SQDCECCRRNTECAPGLGAQHPLQLN 146

Query: 158 QDTLCQNCPPGTFSPN-GTLEECQHQTKCSWL 188
           +DT+C+ C  G FS    + ++C+  T C++L
Sbjct: 147 KDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFL 178


>gi|7657039 tumor necrosis factor receptor superfamily, member 21
           precursor [Homo sapiens]
          Length = 655

 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 44/133 (33%), Positives = 59/133 (44%), Gaps = 8/133 (6%)

Query: 54  CPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRASRNCSR 113
           C KC  G  V E C   +  VC  CP GT+  H NG+ KC  C    P   +     C+ 
Sbjct: 67  CDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCP-WPMIEKLPCAA 125

Query: 114 TENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFSP- 172
             +  C C PG F         A C  +     G  V+K GTE++D  C+ C  GTFS  
Sbjct: 126 LTDRECTCPPGMF------QSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDV 179

Query: 173 NGTLEECQHQTKC 185
             ++ +C+  T C
Sbjct: 180 PSSVMKCKAYTDC 192


>gi|4507569 tumor necrosis factor receptor superfamily, member 25
           isoform 2 precursor [Homo sapiens]
          Length = 417

 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 60/216 (27%), Positives = 85/216 (39%), Gaps = 31/216 (14%)

Query: 25  LYLTFLGAPCY----APALPSCKEDEYPVGSECCPKCSPGYRVKEACGELTG-TVCEPCP 79
           L L  LGA       +P      +    +G  CC  C  G+ +K  C E  G + C  CP
Sbjct: 15  LLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCP 74

Query: 80  PGTYIAHLNGL-SKCLQCQMCDPAMGLRASRNCSRTENAVCGCSPGHF-------CIVQD 131
             T++A  N   S+C +CQ CD      A  NCS   +  CGC PG F       C+   
Sbjct: 75  QDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSS 134

Query: 132 GDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFS--------PNGTLEECQHQT 183
             +C  C          R+       +DT C  C PG +         P  TL  C    
Sbjct: 135 PFYCQPCLDCGALHRHTRLL---CSRRDTDCGTCLPGFYEHGDGCVSCPTSTLGSCPE-- 189

Query: 184 KCSWLVTKAGAGTSSSHWVWWFLSGSLVIVIVCSTV 219
           +C+     A  G     WV   L+G +V +++ +T+
Sbjct: 190 RCA-----AVCGWRQMFWVQVLLAGLVVPLLLGATL 220


>gi|23200023 tumor necrosis factor receptor superfamily, member 25
           isoform 3 precursor [Homo sapiens]
          Length = 380

 Score = 72.8 bits (177), Expect = 3e-13
 Identities = 55/192 (28%), Positives = 73/192 (38%), Gaps = 26/192 (13%)

Query: 25  LYLTFLGAPCY----APALPSCKEDEYPVGSECCPKCSPGYRVKEACGELTG-TVCEPCP 79
           L L  LGA       +P      +    +G  CC  C  G+ +K  C E  G + C  CP
Sbjct: 15  LLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCP 74

Query: 80  PGTYIAHLNGL-SKCLQCQMCDPAMGLRASRNCSRTENAVCGCSPGHF-------CIVQD 131
             T++A  N   S+C +CQ CD      A  NCS   +  CGC PG F       C+   
Sbjct: 75  QDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSS 134

Query: 132 GDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFS--------PNGTLEECQHQ- 182
             +C  C          R+       +DT C  C PG +         P  TL  C  + 
Sbjct: 135 PFYCQPCLDCGALHRHTRLL---CSRRDTDCGTCLPGFYEHGDGCVSCPTSTLGSCPERC 191

Query: 183 -TKCSWLVTKAG 193
              C W   +AG
Sbjct: 192 AAVCGWRQNEAG 203


>gi|4505393 nerve growth factor receptor precursor [Homo sapiens]
          Length = 427

 Score = 72.0 bits (175), Expect = 5e-13
 Identities = 50/163 (30%), Positives = 73/163 (44%), Gaps = 14/163 (8%)

Query: 24  VLYLTFLGAPCYAPALPSCKEDEYPVGSECCPKCSPGYRVKEACGELTGTVCEPCPPGTY 83
           +L L  LG      A  +C    Y    ECC  C+ G  V + CG    TVCEPC     
Sbjct: 15  LLLLLLLGVSL-GGAKEACPTGLYTHSGECCKACNLGEGVAQPCGA-NQTVCEPCLDSVT 72

Query: 84  IAHLNGLSKCLQCQMCDPAMGLRA-SRNCSRTENAVCGCSPGHFCIVQDGDHCAACRAYA 142
            + +  +S    C+ C   +GL++ S  C   ++AVC C+ G++     G  C ACR   
Sbjct: 73  FSDV--VSATEPCKPCTECVGLQSMSAPCVEADDAVCRCAYGYYQDETTG-RCEACRV-- 127

Query: 143 TSSPGQRVQKGGTESQDTLCQNCPPGTFSPNGTLEECQHQTKC 185
               G  +     + Q+T+C+ CP GT+S     +E  H   C
Sbjct: 128 -CEAGSGLVFSCQDKQNTVCEECPDGTYS-----DEANHVDPC 164



 Score = 58.2 bits (139), Expect = 8e-09
 Identities = 34/106 (32%), Positives = 46/106 (43%), Gaps = 8/106 (7%)

Query: 27  LTFLGAPCYAPALPSCK------EDEYPVGSECCPKCSPGYRVKEACGELTGTVCEPCPP 80
           L  + APC       C+      +DE     E C  C  G  +  +C +   TVCE CP 
Sbjct: 92  LQSMSAPCVEADDAVCRCAYGYYQDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPD 151

Query: 81  GTYIAHLNGLSKCLQCQMCDPAMGLRASRNCSRTENAVCGCSPGHF 126
           GTY    N +  CL C +C+     R  R C+R  +A C   PG +
Sbjct: 152 GTYSDEANHVDPCLPCTVCEDTE--RQLRECTRWADAECEEIPGRW 195


>gi|4507579 tumor necrosis factor receptor superfamily, member 4
           precursor [Homo sapiens]
          Length = 277

 Score = 70.1 bits (170), Expect = 2e-12
 Identities = 42/145 (28%), Positives = 56/145 (38%), Gaps = 27/145 (18%)

Query: 42  CKEDEYPVGSECCPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDP 101
           C  D YP    CC +C PG  +   C     TVC PC PG Y   ++    C  C  C+ 
Sbjct: 31  CVGDTYPSNDRCCHECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSS-KPCKPCTWCNL 89

Query: 102 AMGLRASRNCSRTENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTL 161
             G    + C+ T++ VC C  G              +   +  PG              
Sbjct: 90  RSGSERKQLCTATQDTVCRCRAG-------------TQPLDSYKPG------------VD 124

Query: 162 CQNCPPGTFSPNGTLEECQHQTKCS 186
           C  CPPG FSP G  + C+  T C+
Sbjct: 125 CAPCPPGHFSP-GDNQACKPWTNCT 148



 Score = 30.8 bits (68), Expect = 1.4
 Identities = 16/60 (26%), Positives = 30/60 (50%), Gaps = 9/60 (15%)

Query: 135 CAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFSPNGTLEECQHQTKCSWLVTKAGA 194
           C  CR      PG  +    + SQ+T+C+ C PG ++   + + C+    C+W   ++G+
Sbjct: 43  CHECR------PGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCK---PCTWCNLRSGS 93


>gi|4507583 tumor necrosis factor receptor superfamily, member 6
           isoform 1 precursor [Homo sapiens]
          Length = 335

 Score = 68.2 bits (165), Expect = 8e-12
 Identities = 57/234 (24%), Positives = 88/234 (37%), Gaps = 56/234 (23%)

Query: 50  GSECCPKCSPGYRVKEACGELTGTV--CEPCPPGT-YIAHLNGLSKCLQCQMCDPAMGLR 106
           G  C   C PG R    C  + G    C PC  G  Y    +  SKC +C++CD   GL 
Sbjct: 56  GQFCHKPCPPGERKARDC-TVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLE 114

Query: 107 ASRNCSRTENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCP 166
              NC+RT+N  C C P  FC                                T+C++C 
Sbjct: 115 VEINCTRTQNTKCRCKPNFFC------------------------------NSTVCEHCD 144

Query: 167 PGTFSPNGTLEEC--QHQTKCSWLVTKAGAGTSSSHWVWWFLSGSLVIVIVCSTVGLIIC 224
           P T   +G ++EC     TKC     K     S+  W          + ++   + LI+ 
Sbjct: 145 PCTKCEHGIIKECTLTSNTKC-----KEEGSRSNLGW----------LCLLLLPIPLIVW 189

Query: 225 VKRRKPRGDVVKVIVSVQRKRQEAEGEATVIEALQAPPDVTTVAVEETIPSFTG 278
           VKR++     V+      RK  +   E+  +       +++ V + + I +  G
Sbjct: 190 VKRKE-----VQKTCRKHRKENQGSHESPTLNPETVAINLSDVDLSKYITTIAG 238


>gi|23200021 tumor necrosis factor receptor superfamily, member 25
           isoform 1 precursor [Homo sapiens]
          Length = 426

 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 57/218 (26%), Positives = 83/218 (38%), Gaps = 26/218 (11%)

Query: 25  LYLTFLGAPCY----APALPSCKEDEYPVGSECCPKCSPGYRVKEACGELTG-TVCEPCP 79
           L L  LGA       +P      +    +G  CC  C  G+ +K  C E  G + C  CP
Sbjct: 15  LLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCP 74

Query: 80  PGTYIAHLNGL-SKCLQCQMCDPAMGLRASRNCSRTENAVCGCSPGHF-------CIVQD 131
             T++A  N   S+C +CQ CD      A  NCS   +  CGC PG F       C+   
Sbjct: 75  QDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSS 134

Query: 132 GDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTF----------SPNGTLEECQH 181
             +C  C          R+       +DT C  C PG +          +P  +L     
Sbjct: 135 PFYCQPCLDCGALHRHTRLL---CSRRDTDCGTCLPGFYEHGDGCVSCPTPPPSLAGAPW 191

Query: 182 QTKCSWLVTKAGAGTSSSHWVWWFLSGSLVIVIVCSTV 219
               S +      G     WV   L+G +V +++ +T+
Sbjct: 192 GAVQSAVPLSVAGGRVGVFWVQVLLAGLVVPLLLGATL 229


>gi|23510423 tumor necrosis factor receptor superfamily, member 6
           isoform 3 precursor [Homo sapiens]
          Length = 220

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 53/185 (28%), Positives = 69/185 (37%), Gaps = 41/185 (22%)

Query: 50  GSECCPKCSPGYRVKEACGELTGTV--CEPCPPGT-YIAHLNGLSKCLQCQMCDPAMGLR 106
           G  C   C PG R    C  + G    C PC  G  Y    +  SKC +C++CD   GL 
Sbjct: 56  GQFCHKPCPPGERKARDC-TVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLE 114

Query: 107 ASRNCSRTENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCP 166
              NC+RT+N  C C P  FC                                T+C++C 
Sbjct: 115 VEINCTRTQNTKCRCKPNFFC------------------------------NSTVCEHCD 144

Query: 167 PGTFSPNGTLEEC--QHQTKCSWLVTKAGAGTSSSHWVWWFLSGSLVIVIVCSTVGLIIC 224
           P T   +G ++EC     TKC     K     S+  W+   L    +IV V        C
Sbjct: 145 PCTKCEHGIIKECTLTSNTKC-----KEEGSRSNLGWLCLLLLPIPLIVWVKRKEVQKTC 199

Query: 225 VKRRK 229
            K RK
Sbjct: 200 RKHRK 204


>gi|89142745 tumor necrosis factor receptor superfamily, member 25
           isoform 12 precursor [Homo sapiens]
          Length = 181

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 48/168 (28%), Positives = 64/168 (38%), Gaps = 16/168 (9%)

Query: 25  LYLTFLGAPCY----APALPSCKEDEYPVGSECCPKCSPGYRVKEACGELTG-TVCEPCP 79
           L L  LGA       +P      +    +G  CC  C  G+ +K  C E  G + C  CP
Sbjct: 15  LLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCP 74

Query: 80  PGTYIAHLNGL-SKCLQCQMCDPAMGLRASRNCSRTENAVCGCSPGHF-------CIVQD 131
             T++A  N   S+C +CQ CD      A  NCS   +  CGC PG F       C+   
Sbjct: 75  QDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSS 134

Query: 132 GDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFSPNGTLEEC 179
             +C  C          R+       +DT C  C PG +        C
Sbjct: 135 PFYCQPCLDCGALHRHTRLL---CSRRDTDCGTCLPGFYEHGDGCVSC 179


>gi|23510421 tumor necrosis factor receptor superfamily, member 6
           isoform 2 precursor [Homo sapiens]
          Length = 314

 Score = 65.5 bits (158), Expect = 5e-11
 Identities = 42/141 (29%), Positives = 55/141 (39%), Gaps = 36/141 (25%)

Query: 50  GSECCPKCSPGYRVKEACGELTGTV--CEPCPPGT-YIAHLNGLSKCLQCQMCDPAMGLR 106
           G  C   C PG R    C  + G    C PC  G  Y    +  SKC +C++CD   GL 
Sbjct: 56  GQFCHKPCPPGERKARDC-TVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLE 114

Query: 107 ASRNCSRTENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCP 166
              NC+RT+N  C C P  FC                                T+C++C 
Sbjct: 115 VEINCTRTQNTKCRCKPNFFC------------------------------NSTVCEHCD 144

Query: 167 PGTFSPNGTLEEC--QHQTKC 185
           P T   +G ++EC     TKC
Sbjct: 145 PCTKCEHGIIKECTLTSNTKC 165


>gi|68348711 tumor necrosis factor receptor superfamily, member 8
           isoform 1 precursor [Homo sapiens]
          Length = 595

 Score = 62.0 bits (149), Expect = 6e-10
 Identities = 33/128 (25%), Positives = 53/128 (41%), Gaps = 4/128 (3%)

Query: 53  CCPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRASRNCS 112
           CC +C  G    + C +      + C P  Y+   +  + C+ C   D    L     C+
Sbjct: 44  CCYRCPMGLFPTQQCPQRPTDCRKQCEPDYYLDEADRCTACVTCSRDD----LVEKTPCA 99

Query: 113 RTENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFSP 172
              + VC C PG FC     + CA C  ++    G  V+  GT  ++T+C+   PG    
Sbjct: 100 WNSSRVCECRPGMFCSTSAVNSCARCFFHSVCPAGMIVKFPGTAQKNTVCEPASPGVSPA 159

Query: 173 NGTLEECQ 180
             + E C+
Sbjct: 160 CASPENCK 167



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 46/197 (23%), Positives = 70/197 (35%), Gaps = 31/197 (15%)

Query: 55  PKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRASRNCSRT 114
           P   PG    + C E +G   + C P  Y+      + C+ C   D       + N SRT
Sbjct: 221 PSSDPGLSPTQPCPEGSGDCRKQCEPDYYLDEAGRCTACVSCSRDDLVEKTPCAWNSSRT 280

Query: 115 ENAVCGCSPGHFCIVQDGDHCAACRAY------ATSSPGQRVQKGGTESQDTL-----CQ 163
               C C PG  C     +  A C  Y        + P    +K  T     L     C 
Sbjct: 281 ----CECRPGMICATSATNSRARCVPYPICAAETVTKPQDMAEKDTTFEAPPLGTQPDCN 336

Query: 164 NCP-----PGTFSPNGTLEECQHQTKCSWLVTKAGAGTSSS--------HWVWWFLSGSL 210
             P     P + SP  +L      +K   + T A    SS+          ++W +   L
Sbjct: 337 PTPENGEAPASTSPTQSLLVDSQASKTLPIPTSAPVALSSTGKPVLDAGPVLFWVI---L 393

Query: 211 VIVIVCSTVGLIICVKR 227
           V+V+V  +   ++C +R
Sbjct: 394 VLVVVVGSSAFLLCHRR 410


>gi|5730095 tumor necrosis factor receptor superfamily, member 9
           precursor [Homo sapiens]
          Length = 255

 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 40/133 (30%), Positives = 55/133 (41%), Gaps = 20/133 (15%)

Query: 54  CPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRASRNCSR 113
           C  C  G      C      +C PCPP ++ +   G   C  C+ C      R  + CS 
Sbjct: 28  CSNCPAG----TFCDNNRNQICSPCPPNSF-SSAGGQRTCDICRQCKGVF--RTRKECSS 80

Query: 114 TENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFSPN 173
           T NA C C+PG  C+   G  C+ C        GQ + K G       C++C  GTF+ +
Sbjct: 81  TSNAECDCTPGFHCL---GAGCSMCE--QDCKQGQELTKKG-------CKDCCFGTFN-D 127

Query: 174 GTLEECQHQTKCS 186
                C+  T CS
Sbjct: 128 QKRGICRPWTNCS 140


>gi|22547108 tumor necrosis factor receptor superfamily, member 10d
           precursor [Homo sapiens]
          Length = 386

 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 47/165 (28%), Positives = 67/165 (40%), Gaps = 17/165 (10%)

Query: 8   GPPPWRSTPKTDVLRLVLYLTFLGAPCYAPALPSCKEDEYPVGSECCPKCSPGYRVKEAC 67
           G  PW   PK  +L+ V+++  +  P    +    ++DE P  +   P+       +E C
Sbjct: 27  GTRPWLLDPK--ILKFVVFIVAVLLPVRVDSATIPRQDEVPQQT-VAPQQQRRSLKEEEC 83

Query: 68  ------GELTGTVCEPCPPGT-YIAHLNGLSKCLQCQMCDPAMGLRASRNCSRTENAVCG 120
                  E TG  C PC  G  Y    N L  CL C +C      ++S  C+ T + VC 
Sbjct: 84  PAGSHRSEYTGA-CNPCTEGVDYTIASNNLPSCLLCTVCKSGQTNKSS--CTTTRDTVCQ 140

Query: 121 CSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGG-TESQDTLCQN 164
           C  G F   QD +    CR   T  P   V+    T   D  C+N
Sbjct: 141 CEKGSF---QDKNSPEMCRTCRTGCPRGMVKVSNCTPRSDIKCKN 182


>gi|4507587 tumor necrosis factor receptor superfamily, member 7
           precursor [Homo sapiens]
          Length = 260

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 33/102 (32%), Positives = 46/102 (45%), Gaps = 6/102 (5%)

Query: 37  PALPSCKEDEY-PVGSECCPKCSPG-YRVKEACGELTGTVCEPCPPG-TYIAHLNGLSKC 93
           PA  SC E  Y   G  CC  C PG + VK+         C+PC PG ++    +    C
Sbjct: 22  PAPKSCPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHC 81

Query: 94  LQCQMCDPAMGLRASRNCSRTENAVCGCSPGHFCIVQDGDHC 135
             C+ C+  + +R   NC+ T NA C C  G  C  ++   C
Sbjct: 82  ESCRHCNSGLLVR---NCTITANAECACRNGWQCRDKECTEC 120


>gi|4507575 tumor necrosis factor receptor 1 precursor [Homo
           sapiens]
          Length = 455

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 38/137 (27%), Positives = 50/137 (36%), Gaps = 8/137 (5%)

Query: 51  SECCPKCSPG-YRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRASR 109
           S CC KC  G Y   +  G    T C  C  G++ A  N L  CL C  C   MG     
Sbjct: 56  SICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEIS 115

Query: 110 NCSRTENAVCGCSPGHFCIVQDGD--HCAACRAYATSSPGQRVQKGGTESQDTLCQNCPP 167
           +C+   + VCGC    +      +   C  C      +    V     E Q+T+C  C  
Sbjct: 116 SCTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCLNGT----VHLSCQEKQNTVC-TCHA 170

Query: 168 GTFSPNGTLEECQHQTK 184
           G F        C +  K
Sbjct: 171 GFFLRENECVSCSNCKK 187


>gi|224494019 tumor necrosis factor receptor superfamily, member 10b
           isoform 1 precursor [Homo sapiens]
          Length = 440

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 51/171 (29%), Positives = 64/171 (37%), Gaps = 21/171 (12%)

Query: 8   GPPPWRSTPKTDVLRLVLYLTFLGAPC-------YAPALPSCKEDEYPVGSECCPKCSPG 60
           G  P    PKT VL +   L  + A          AP   +  + +    SE    C PG
Sbjct: 27  GARPGPRVPKTLVLVVAAVLLLVSAESALITQQDLAPQQRAAPQQKRSSPSEGL--CPPG 84

Query: 61  YRVKEACGELTGTVCEPCPPGT-YIAHLNGLSKCLQCQMCDPAMGLRASRNCSRTENAVC 119
           + + E      G  C  C  G  Y  H N L  CL+C  CD   G      C+ T N VC
Sbjct: 85  HHISE-----DGRDCISCKYGQDYSTHWNDLLFCLRCTRCDS--GEVELSPCTTTRNTVC 137

Query: 120 GCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGG-TESQDTLCQNCPPGT 169
            C  G F   ++ D    CR   T  P   V+ G  T   D  C +   GT
Sbjct: 138 QCEEGTF---REEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKESGT 185


>gi|224494026 tumor necrosis factor receptor superfamily, member 10b
           isoform 2 precursor [Homo sapiens]
          Length = 411

 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 46/154 (29%), Positives = 58/154 (37%), Gaps = 20/154 (12%)

Query: 8   GPPPWRSTPKTDVLRLVLYLTFLGAPC-------YAPALPSCKEDEYPVGSECCPKCSPG 60
           G  P    PKT VL +   L  + A          AP   +  + +    SE    C PG
Sbjct: 27  GARPGPRVPKTLVLVVAAVLLLVSAESALITQQDLAPQQRAAPQQKRSSPSEGL--CPPG 84

Query: 61  YRVKEACGELTGTVCEPCPPGT-YIAHLNGLSKCLQCQMCDPAMGLRASRNCSRTENAVC 119
           + + E      G  C  C  G  Y  H N L  CL+C  CD   G      C+ T N VC
Sbjct: 85  HHISE-----DGRDCISCKYGQDYSTHWNDLLFCLRCTRCDS--GEVELSPCTTTRNTVC 137

Query: 120 GCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKG 153
            C  G F   ++ D    CR   T  P   V+ G
Sbjct: 138 QCEEGTF---REEDSPEMCRKCRTGCPRGMVKVG 168


>gi|11140823 X-linked ectodysplasin receptor [Homo sapiens]
          Length = 297

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 38/118 (32%), Positives = 51/118 (43%), Gaps = 14/118 (11%)

Query: 42  CKEDEY-PVGSEC--CPKCSPGYRVKEACGELTG--TVCEPCPPGTYIAHLNGLSKCLQC 96
           C+E+EY      C  C +C PG  + + CG   G    C  CPP  Y +   G  +C  C
Sbjct: 3   CQENEYWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSW-GHHRCQSC 61

Query: 97  QMCDPAMGLRASR-NCSRTENAVCG-CSPGHFCIVQDG----DHCAACRAYATSSPGQ 148
             C  A+  R  + NC+ T NAVCG C P  +   + G      C  C     +S  Q
Sbjct: 62  ITC--AVINRVQKVNCTATSNAVCGDCLPRFYRKTRIGGLQDQECIPCTKQTPTSEVQ 117



 Score = 29.3 bits (64), Expect = 4.1
 Identities = 16/56 (28%), Positives = 20/56 (35%), Gaps = 2/56 (3%)

Query: 133 DHCAACRAYATSSPGQRVQK--GGTESQDTLCQNCPPGTFSPNGTLEECQHQTKCS 186
           D    C       PGQ + K  G  E  D  C  CPP  +  +     CQ    C+
Sbjct: 10  DQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHRCQSCITCA 65


>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
          Length = 1575

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 49/167 (29%), Positives = 62/167 (37%), Gaps = 34/167 (20%)

Query: 8   GPPPWRSTPKTDVLRLVLYLTFLGAPCYAPALPSCKEDEYPVG--SECCPKCSPGYRVKE 65
           GP P      T+V RL      L  P     + SC     P G   + C  C+PGY+ + 
Sbjct: 642 GPSPAGPVFLTEV-RLTSARPGLSPPASWVEICSC-----PTGYTGQFCESCAPGYKREM 695

Query: 66  ACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRASRNCSR-TENAVCG-CSP 123
             G    + C PC              C Q   CDP  G+     CS  TE   C  C P
Sbjct: 696 PQGGPYAS-CVPCT-------------CNQHGTCDPNTGICV---CSHHTEGPSCERCLP 738

Query: 124 GHFC--IVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPG 168
           G +        D C  C       PGQ       ES++ +C +CPPG
Sbjct: 739 GFYGNPFAGQADDCQPCPC-----PGQSACTTIPESREVVCTHCPPG 780



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 36/117 (30%), Positives = 45/117 (38%), Gaps = 38/117 (32%)

Query: 41   SCKEDEYPVGSE---CCPK-----CSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSK 92
            SCK   +P+GS+   C PK     C PG         +TG  C+ C  G +   + G   
Sbjct: 916  SCKC--HPLGSQEDQCHPKTGQCTCRPG---------VTGQACDRCQLGFFGFSIKGCRA 964

Query: 93   CLQCQMCDPAMGLRASRNCSRTENAVCGCSPG-----------HFCIVQDGDHCAAC 138
            C     C P     AS  C   EN  C C PG           +F +  DG HC  C
Sbjct: 965  C----RCSPLGA--ASAQCH--ENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQC 1013



 Score = 33.5 bits (75), Expect = 0.22
 Identities = 34/144 (23%), Positives = 46/144 (31%), Gaps = 35/144 (24%)

Query: 52  ECCPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCD----------- 100
           +C P   PG        E    VC  CPPG          +  +C++CD           
Sbjct: 751 DCQPCPCPGQSACTTIPESREVVCTHCPPG---------QRGRRCEVCDDGFFGDPLGLF 801

Query: 101 ----PAMGLRASRNCSRTENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKG--G 154
               P    + S N     NAV  C P          HC  C    T    +  Q+G  G
Sbjct: 802 GHPQPCHQCQCSGNVD--PNAVGNCDP-------LSGHCLRCLHNTTGDHCEHCQEGFYG 852

Query: 155 TESQDTLCQNCPPGTFSPNGTLEE 178
           +         C P +  P G++ E
Sbjct: 853 SALAPRPADKCMPCSCHPQGSVSE 876



 Score = 29.6 bits (65), Expect = 3.1
 Identities = 33/150 (22%), Positives = 41/150 (27%), Gaps = 22/150 (14%)

Query: 37  PALPSCKEDEYPVGSECCPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQC 96
           P   S + +E     E       G R         G  CE C    Y          + C
Sbjct: 326 PCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFY-----HWDPRMPC 380

Query: 97  QMCDPAMGLRASRNCSRTENAVCG----------CSPGHFCIVQDGDHCAACRAYATSSP 146
           Q CD          C  T    C           C PG   + + G  C  C      S 
Sbjct: 381 QPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGG--CRPCTCNPAGSL 438

Query: 147 GQRVQKGGT-----ESQDTLCQNCPPGTFS 171
                + G        +  LC  C PGTF+
Sbjct: 439 DTCDPRSGRCPCKENVEGNLCDRCRPGTFN 468


>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
          Length = 1541

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 47/166 (28%), Positives = 56/166 (33%), Gaps = 32/166 (19%)

Query: 31   GAPCYAPALPSCKEDEY--PVGSECCPKCSPGYRVKEACGELTGTVCE-PCPPGTYIAHL 87
            GA C+     SC  +    P    C  +C PG+          G  CE PCPPG + A  
Sbjct: 1341 GAACHLEC--SCHNNSTCEPATGTC--RCGPGFY---------GQACEHPCPPGFHGAGC 1387

Query: 88   NGLSKCLQCQMCDPAMGLRASRNCSRTENAVCGCSPGHF-------CIVQDGDHCAACRA 140
             GL  C     CDP  G               GC PG F       C    G  C     
Sbjct: 1388 QGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTG 1447

Query: 141  YATSSPGQRVQKGGTESQDTLCQNCPPGTFSPNGTLE-ECQHQTKC 185
                 PG   + G T + D     C  G F P+ TL  +C     C
Sbjct: 1448 LCLCPPG---RSGATCNLD-----CRRGQFGPSCTLHCDCGGGADC 1485



 Score = 36.2 bits (82), Expect = 0.033
 Identities = 37/118 (31%), Positives = 45/118 (38%), Gaps = 17/118 (14%)

Query: 71  TGTVC-EPCPPGTYIAHLNGLSKCLQCQMCDPAMG-LRASRNCSRTENAVCGCSPGHFCI 128
           TG +C E CPP T+  + +    C     CD   G  R     S T N   GC  G++  
Sbjct: 547 TGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGT-NCEDGCPKGYY-- 603

Query: 129 VQDGDHC-----AACRAYATSSPGQRVQKGGTESQDTLCQ-NCPPGTFSPNGTLEECQ 180
              G HC      A R       G  +   G   +   C   CPP  F P G  EECQ
Sbjct: 604 ---GKHCRKKCNCANRGRCHRLYGACLCDPGLYGR--FCHLTCPPWAFGP-GCSEECQ 655



 Score = 35.4 bits (80), Expect = 0.057
 Identities = 48/201 (23%), Positives = 59/201 (29%), Gaps = 70/201 (34%)

Query: 48   PVGSECCPKCSPGYRVKEACGELTGTVCEP-------------------CPPGTYIAHLN 88
            P  +E CP  + G+   +AC    G  C+P                   CP G Y  +  
Sbjct: 984  PRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCR 1043

Query: 89   GLSKCLQCQMCDPA----------MGLRASRNC-SRTENAVC----GCSPGHFCIVQ--- 130
                C     CDP            GL   + C  R   A C    GC  G  C      
Sbjct: 1044 HSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGR 1103

Query: 131  -------DGDHC----------AACRAYATSSPGQ---------RVQKGGTESQDTLCQN 164
                    GD C           AC    +  PG          R   G T S     Q 
Sbjct: 1104 CLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCE--QA 1161

Query: 165  CPPGTFSPNGTLEECQHQTKC 185
            CPPG+F      E+C    +C
Sbjct: 1162 CPPGSFG-----EDCAQMCQC 1177



 Score = 35.4 bits (80), Expect = 0.057
 Identities = 43/168 (25%), Positives = 53/168 (31%), Gaps = 47/168 (27%)

Query: 42   CKEDEYPVGSECCPKCSPGYRVKEACGEL------TGTVCE-PCPPGTYIAHLNGLSKCL 94
            C ++ + VG E    C  G     + G        TG  CE  CPPG Y A  +    C 
Sbjct: 1292 CPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCH 1351

Query: 95   QCQMCDPAMGLRASRNCSRTENAVCGCSPG-------HFCIVQDGDHCAACRAYATSSPG 147
                C+PA G              C C PG       H C    G H A C+       G
Sbjct: 1352 NNSTCEPATG-------------TCRCGPGFYGQACEHPC--PPGFHGAGCQGLCWCQHG 1396

Query: 148  QRVQKGGTESQDTLC----------QNCPPGTFSPNGTLEECQHQTKC 185
                     S   LC          + C PG+F      E C  +  C
Sbjct: 1397 APCD---PISGRCLCPAGFHGHFCERGCEPGSFG-----EGCHQRCDC 1436



 Score = 35.0 bits (79), Expect = 0.074
 Identities = 44/181 (24%), Positives = 53/181 (29%), Gaps = 50/181 (27%)

Query: 29   FLGAPCYAPALPSCKEDEYPVGSECC---PKCSPGYRVKEACGELTGTVCEP-CPPGTYI 84
            F G+ C     P    ++     +C    P C P            G  C+  CPPG Y 
Sbjct: 1153 FTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYG 1212

Query: 85   AHLNGLSKCLQCQMCDPAMGL-------------------RASRNCSRTENAVCGCSPGH 125
                 L  CL    CD A G                    R   NC+     VCGC  G 
Sbjct: 1213 PGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTH----VCGCGQGA 1268

Query: 126  FCIVQDGD-HCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFSPNGTLEECQHQTK 184
             C    G   C   RA      G R ++G           CP   F        C+H   
Sbjct: 1269 ACDPVTGTCLCPPGRA------GVRCERG-----------CPQNRFGVG-----CEHTCS 1306

Query: 185  C 185
            C
Sbjct: 1307 C 1307


>gi|23200025 tumor necrosis factor receptor superfamily, member 25
           isoform 4 precursor [Homo sapiens]
          Length = 372

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 37/139 (26%), Positives = 53/139 (38%), Gaps = 26/139 (18%)

Query: 96  CQMCDPAMGLRASRNCSRTENAVCGCSPGHF-------CIVQDGDHCAACRAYATSSPGQ 148
           C+ C PA    A  NCS   +  CGC PG F       C+     +C  C          
Sbjct: 48  CRGC-PAASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHT 106

Query: 149 RVQKGGTESQDTLCQNCPPGTFS--------PNGTLEECQHQTKCSWLVTKAGAGTSSSH 200
           R+       +DT C  C PG +         P  TL  C    +C+     A  G     
Sbjct: 107 RLL---CSRRDTDCGTCLPGFYEHGDGCVSCPTSTLGSCPE--RCA-----AVCGWRQMF 156

Query: 201 WVWWFLSGSLVIVIVCSTV 219
           WV   L+G +V +++ +T+
Sbjct: 157 WVQVLLAGLVVPLLLGATL 175


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.455 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,996,442
Number of Sequences: 37866
Number of extensions: 800043
Number of successful extensions: 2710
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 143
Number of HSP's that attempted gapping in prelim test: 2269
Number of HSP's gapped (non-prelim): 486
length of query: 283
length of database: 18,247,518
effective HSP length: 101
effective length of query: 182
effective length of database: 14,423,052
effective search space: 2624995464
effective search space used: 2624995464
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.