Search of human proteins with 23200021

Search of human proteins with 23200021

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23200021 tumor necrosis factor receptor superfamily, member
25 isoform 1 precursor [Homo sapiens]
         (426 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23200021 tumor necrosis factor receptor superfamily, member 2...   912   0.0  
gi|4507569 tumor necrosis factor receptor superfamily, member 25...   847   0.0  
gi|23200023 tumor necrosis factor receptor superfamily, member 2...   754   0.0  
gi|23200025 tumor necrosis factor receptor superfamily, member 2...   720   0.0  
gi|89142745 tumor necrosis factor receptor superfamily, member 2...   409   e-114
gi|23200031 tumor necrosis factor receptor superfamily, member 2...   376   e-104
gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapi...   130   2e-30
gi|23200041 tumor necrosis factor receptor superfamily, member 1...    68   2e-11
gi|23510423 tumor necrosis factor receptor superfamily, member 6...    65   9e-11
gi|23510421 tumor necrosis factor receptor superfamily, member 6...    65   9e-11
gi|4507583 tumor necrosis factor receptor superfamily, member 6 ...    65   9e-11
gi|224494019 tumor necrosis factor receptor superfamily, member ...    64   2e-10
gi|224494026 tumor necrosis factor receptor superfamily, member ...    60   4e-09
gi|4507565 tumor necrosis factor receptor superfamily, member 11...    59   1e-08
gi|4507587 tumor necrosis factor receptor superfamily, member 7 ...    54   4e-07
gi|4505039 lymphotoxin beta receptor [Homo sapiens]                    54   4e-07
gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens]    51   2e-06
gi|23238204 tumor necrosis factor receptor superfamily, member 1...    51   2e-06
gi|23238202 tumor necrosis factor receptor superfamily, member 1...    51   2e-06
gi|4507577 tumor necrosis factor receptor 2 precursor [Homo sapi...    49   9e-06
gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]             48   2e-05
gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]            48   2e-05
gi|7657039 tumor necrosis factor receptor superfamily, member 21...    47   3e-05
gi|148743793 osteoprotegerin precursor [Homo sapiens]                  45   1e-04
gi|21361086 tumor necrosis factor receptor superfamily, member 1...    44   4e-04
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]               42   8e-04
gi|4507579 tumor necrosis factor receptor superfamily, member 4 ...    41   0.002
gi|56676397 ankyrin repeat domain 11 [Homo sapiens]                    41   0.002
gi|14790170 tumor necrosis factor receptor superfamily, member 6...    41   0.002
gi|4507585 tumor necrosis factor receptor superfamily, member 6b...    41   0.002

>gi|23200021 tumor necrosis factor receptor superfamily, member 25
           isoform 1 precursor [Homo sapiens]
          Length = 426

 Score =  912 bits (2358), Expect = 0.0
 Identities = 426/426 (100%), Positives = 426/426 (100%)

Query: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60
           MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP
Sbjct: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60

Query: 61  CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120
           CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG
Sbjct: 61  CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120

Query: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180
           WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
Sbjct: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180

Query: 181 TPPPSLAGAPWGAVQSAVPLSVAGGRVGVFWVQVLLAGLVVPLLLGATLTYTYRHCWPHK 240
           TPPPSLAGAPWGAVQSAVPLSVAGGRVGVFWVQVLLAGLVVPLLLGATLTYTYRHCWPHK
Sbjct: 181 TPPPSLAGAPWGAVQSAVPLSVAGGRVGVFWVQVLLAGLVVPLLLGATLTYTYRHCWPHK 240

Query: 241 PLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEA 300
           PLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEA
Sbjct: 241 PLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEA 300

Query: 301 LCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFV 360
           LCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFV
Sbjct: 301 LCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFV 360

Query: 361 RTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRS 420
           RTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRS
Sbjct: 361 RTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRS 420

Query: 421 RLQRGP 426
           RLQRGP
Sbjct: 421 RLQRGP 426


>gi|4507569 tumor necrosis factor receptor superfamily, member 25
           isoform 2 precursor [Homo sapiens]
          Length = 417

 Score =  847 bits (2189), Expect = 0.0
 Identities = 403/426 (94%), Positives = 406/426 (95%), Gaps = 9/426 (2%)

Query: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60
           MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP
Sbjct: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60

Query: 61  CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120
           CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG
Sbjct: 61  CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120

Query: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180
           WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
Sbjct: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180

Query: 181 TPPPSLAGAPWGAVQSAVPLSVAGGRVGVFWVQVLLAGLVVPLLLGATLTYTYRHCWPHK 240
           T   +L   P          +V G R  +FWVQVLLAGLVVPLLLGATLTYTYRHCWPHK
Sbjct: 181 TS--TLGSCPERCA------AVCGWRQ-MFWVQVLLAGLVVPLLLGATLTYTYRHCWPHK 231

Query: 241 PLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEA 300
           PLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEA
Sbjct: 232 PLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEA 291

Query: 301 LCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFV 360
           LCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFV
Sbjct: 292 LCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFV 351

Query: 361 RTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRS 420
           RTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRS
Sbjct: 352 RTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRS 411

Query: 421 RLQRGP 426
           RLQRGP
Sbjct: 412 RLQRGP 417


>gi|23200023 tumor necrosis factor receptor superfamily, member 25
           isoform 3 precursor [Homo sapiens]
          Length = 380

 Score =  754 bits (1948), Expect = 0.0
 Identities = 366/426 (85%), Positives = 369/426 (86%), Gaps = 46/426 (10%)

Query: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60
           MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP
Sbjct: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60

Query: 61  CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120
           CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG
Sbjct: 61  CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120

Query: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180
           WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
Sbjct: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180

Query: 181 TPPPSLAGAPWGAVQSAVPLSVAGGRVGVFWVQVLLAGLVVPLLLGATLTYTYRHCWPHK 240
           T   +L   P          +V G R                                  
Sbjct: 181 T--STLGSCPERCA------AVCGWR---------------------------------- 198

Query: 241 PLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEA 300
                +EAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEA
Sbjct: 199 ----QNEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEA 254

Query: 301 LCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFV 360
           LCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFV
Sbjct: 255 LCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFV 314

Query: 361 RTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRS 420
           RTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRS
Sbjct: 315 RTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRS 374

Query: 421 RLQRGP 426
           RLQRGP
Sbjct: 375 RLQRGP 380


>gi|23200025 tumor necrosis factor receptor superfamily, member 25
           isoform 4 precursor [Homo sapiens]
          Length = 372

 Score =  720 bits (1859), Expect = 0.0
 Identities = 358/426 (84%), Positives = 361/426 (84%), Gaps = 54/426 (12%)

Query: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60
           MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA       
Sbjct: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA------- 53

Query: 61  CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120
                                                 ASQVALENCSAVADTRCGCKPG
Sbjct: 54  --------------------------------------ASQVALENCSAVADTRCGCKPG 75

Query: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180
           WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
Sbjct: 76  WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 135

Query: 181 TPPPSLAGAPWGAVQSAVPLSVAGGRVGVFWVQVLLAGLVVPLLLGATLTYTYRHCWPHK 240
           T   +L   P          +V G R  +FWVQVLLAGLVVPLLLGATLTYTYRHCWPHK
Sbjct: 136 TS--TLGSCPERCA------AVCGWRQ-MFWVQVLLAGLVVPLLLGATLTYTYRHCWPHK 186

Query: 241 PLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEA 300
           PLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEA
Sbjct: 187 PLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEA 246

Query: 301 LCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFV 360
           LCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFV
Sbjct: 247 LCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFV 306

Query: 361 RTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRS 420
           RTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRS
Sbjct: 307 RTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRS 366

Query: 421 RLQRGP 426
           RLQRGP
Sbjct: 367 RLQRGP 372


>gi|89142745 tumor necrosis factor receptor superfamily, member 25
           isoform 12 precursor [Homo sapiens]
          Length = 181

 Score =  409 bits (1051), Expect = e-114
 Identities = 181/181 (100%), Positives = 181/181 (100%)

Query: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60
           MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP
Sbjct: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60

Query: 61  CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120
           CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG
Sbjct: 61  CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120

Query: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180
           WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
Sbjct: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180

Query: 181 T 181
           T
Sbjct: 181 T 181


>gi|23200031 tumor necrosis factor receptor superfamily, member 25
           isoform 7 precursor [Homo sapiens]
          Length = 234

 Score =  376 bits (966), Expect = e-104
 Identities = 182/182 (100%), Positives = 182/182 (100%)

Query: 245 ADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQ 304
           ADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQ
Sbjct: 53  ADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQ 112

Query: 305 VTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLG 364
           VTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLG
Sbjct: 113 VTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLG 172

Query: 365 LREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQR 424
           LREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQR
Sbjct: 173 LREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQR 232

Query: 425 GP 426
           GP
Sbjct: 233 GP 234



 Score =  116 bits (290), Expect = 4e-26
 Identities = 53/53 (100%), Positives = 53/53 (100%)

Query: 1  MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA 53
          MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA
Sbjct: 1  MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA 53


>gi|4507575 tumor necrosis factor receptor 1 precursor [Homo
           sapiens]
          Length = 455

 Score =  130 bits (328), Expect = 2e-30
 Identities = 117/411 (28%), Positives = 157/411 (38%), Gaps = 26/411 (6%)

Query: 29  RSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSE 88
           R   C      H +    CC  C  G YL   C  P  ++ C  C   +F A ENH    
Sbjct: 40  RDSVCPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLR-H 98

Query: 89  CARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALH 148
           C  C  C ++  QV + +C+   DT CGC+       Q     S + F C  C  C  L+
Sbjct: 99  CLSCSKCRKEMGQVEISSCTVDRDTVCGCRKN-----QYRHYWSENLFQCFNCSLC--LN 151

Query: 149 RHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTPPPSLAGAPWGAVQSAVPLSVAGGRVG 208
               L C  +     TC  GF+   + CVSC     SL        Q             
Sbjct: 152 GTVHLSCQEKQNTVCTCHAGFFLRENECVSCSNCKKSLECTKLCLPQIENVKGTEDSGTT 211

Query: 209 VFWVQVLLAGLVVPLLLGATLTYTYRH---------CWPHKPLVTADEAGMEALTPPPAT 259
           V    V+  GL +  LL   L Y Y+          C    P    +  G       P  
Sbjct: 212 VLLPLVIFFGLCLLSLLFIGLMYRYQRWKSKLYSIVCGKSTPEKEGELEGTTTKPLAPNP 271

Query: 260 HLSPLDS-AHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSWDQLPSRALG 318
             SP      TL   P  S    +         P +   +  + P    + D + + AL 
Sbjct: 272 SFSPTPGFTPTLGFSPVPSSTFTSSSTYTPGDCPNFAAPRREVAPPYQGA-DPILATALA 330

Query: 319 --PAAAPTLSPESPAGSPAMMLQPGPQ-LYDVMDAVPARRWKEFVRTLGLREAEIEAVEV 375
             P   P    E  A  P  +    P  LY V++ VP  RWKEFVR LGL + EI+ +E+
Sbjct: 331 SDPIPNPLQKWEDSAHKPQSLDTDDPATLYAVVENVPPLRWKEFVRRLGLSDHEIDRLEL 390

Query: 376 EIGR-FRDQQYEMLKRWRQQQP---AGLGAVYAALERMGLDGCVEDLRSRL 422
           + GR  R+ QY ML  WR++ P   A L  +   L  M L GC+ED+   L
Sbjct: 391 QNGRCLREAQYSMLATWRRRTPRREATLELLGRVLRDMDLLGCLEDIEEAL 441


>gi|23200041 tumor necrosis factor receptor superfamily, member 14
           precursor [Homo sapiens]
          Length = 283

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 57/218 (26%), Positives = 83/218 (38%), Gaps = 26/218 (11%)

Query: 15  LLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCP 74
           L L  LGA       +P      +    +G  CC  C  G+ +K  C E  G + C  CP
Sbjct: 25  LYLTFLGAPCY----APALPSCKEDEYPVGSECCPKCSPGYRVKEACGELTG-TVCEPCP 79

Query: 75  QDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSS 134
             T++A  N   S+C +CQ CD      A  NCS   +  CGC PG F       C+   
Sbjct: 80  PGTYIAHLNGL-SKCLQCQMCDPAMGLRASRNCSRTENAVCGCSPGHF-------CIVQD 131

Query: 135 PFYCQPCLDCGALHRHTRLL---CSRRDTDCGTCLPGFYEHGDGCVSCPTPPPSLAGAPW 191
             +C  C          R+       +DT C  C PG +          +P  +L     
Sbjct: 132 GDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTF----------SPNGTLEECQH 181

Query: 192 GAVQSAVPLSVAGGRVGVFWVQVLLAGLVVPLLLGATL 229
               S +      G     WV   L+G +V +++ +T+
Sbjct: 182 QTKCSWLVTKAGAGTSSSHWVWWFLSGSLVIVIVCSTV 219


>gi|23510423 tumor necrosis factor receptor superfamily, member 6
           isoform 3 precursor [Homo sapiens]
          Length = 220

 Score = 65.5 bits (158), Expect = 9e-11
 Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 7/101 (6%)

Query: 44  GLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVA 103
           G FC + CP G      CT       C+ C +      + H +S+C RC+ CDE      
Sbjct: 56  GQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEV 115

Query: 104 LENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDC 144
             NC+   +T+C CKP +F       C S+   +C PC  C
Sbjct: 116 EINCTRTQNTKCRCKPNFF-------CNSTVCEHCDPCTKC 149


>gi|23510421 tumor necrosis factor receptor superfamily, member 6
           isoform 2 precursor [Homo sapiens]
          Length = 314

 Score = 65.5 bits (158), Expect = 9e-11
 Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 7/101 (6%)

Query: 44  GLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVA 103
           G FC + CP G      CT       C+ C +      + H +S+C RC+ CDE      
Sbjct: 56  GQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEV 115

Query: 104 LENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDC 144
             NC+   +T+C CKP +F       C S+   +C PC  C
Sbjct: 116 EINCTRTQNTKCRCKPNFF-------CNSTVCEHCDPCTKC 149


>gi|4507583 tumor necrosis factor receptor superfamily, member 6
           isoform 1 precursor [Homo sapiens]
          Length = 335

 Score = 65.5 bits (158), Expect = 9e-11
 Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 7/101 (6%)

Query: 44  GLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVA 103
           G FC + CP G      CT       C+ C +      + H +S+C RC+ CDE      
Sbjct: 56  GQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEV 115

Query: 104 LENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDC 144
             NC+   +T+C CKP +F       C S+   +C PC  C
Sbjct: 116 EINCTRTQNTKCRCKPNFF-------CNSTVCEHCDPCTKC 149


>gi|224494019 tumor necrosis factor receptor superfamily, member 10b
           isoform 1 precursor [Homo sapiens]
          Length = 440

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 97/385 (25%), Positives = 138/385 (35%), Gaps = 80/385 (20%)

Query: 51  CPAGHYLKAPCTEPCGNSTCLVCP--QDTFLAWENHHNSECARCQACDEQASQVALENCS 108
           CP GH++     +      C+ C   QD    W +     C RC  CD  + +V L  C+
Sbjct: 81  CPPGHHISEDGRD------CISCKYGQDYSTHWNDL--LFCLRCTRCD--SGEVELSPCT 130

Query: 109 AVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLP- 167
              +T C C+ G F E         SP  C+ C          R  C R     G C P 
Sbjct: 131 TTRNTVCQCEEGTFRE-------EDSPEMCRKC----------RTGCPRGMVKVGDCTPW 173

Query: 168 ----------GFYEHGD---------GCVSCPTPPPSLAGAPWGAVQSAVPLSVAGGRVG 208
                     G    G+              P  P SL+G   G   +AV L VA     
Sbjct: 174 SDIECVHKESGTKHSGEVPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVA----- 228

Query: 209 VFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAGMEALTPPPATHLSPLDSAH 268
           VF  + LL   V+P L G                   D   ++  +  P    + L+   
Sbjct: 229 VFVCKSLLWKKVLPYLKGICSGGG------------GDPERVDRSSQRPGAEDNVLNEIV 276

Query: 269 TLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSWDQLPSRALGPAAAPTLSPE 328
           ++L P    E+   VQ       P  P     L P  +    + P+ A        L P 
Sbjct: 277 SILQPTQVPEQEMEVQ------EPAEPTGVNMLSPGESEHLLE-PAEAERSQRRRLLVPA 329

Query: 329 SPAGSPAMMLQPGPQLYD-VMDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEM 387
           +  G P   L+   Q +D   D VP   W+  +R LGL + EI+  + E    RD  Y M
Sbjct: 330 NE-GDPTETLR---QCFDDFADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTM 385

Query: 388 LKRW--RQQQPAGLGAVYAALERMG 410
           L +W  +  + A +  +  ALE +G
Sbjct: 386 LIKWVNKTGRDASVHTLLDALETLG 410


>gi|224494026 tumor necrosis factor receptor superfamily, member 10b
           isoform 2 precursor [Homo sapiens]
          Length = 411

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 92/365 (25%), Positives = 133/365 (36%), Gaps = 69/365 (18%)

Query: 51  CPAGHYLKAPCTEPCGNSTCLVCP--QDTFLAWENHHNSECARCQACDEQASQVALENCS 108
           CP GH++     +      C+ C   QD    W +     C RC  CD  + +V L  C+
Sbjct: 81  CPPGHHISEDGRD------CISCKYGQDYSTHWNDL--LFCLRCTRCD--SGEVELSPCT 130

Query: 109 AVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPG 168
              +T C C+ G F E         SP  C+ C          R  C R     G C P 
Sbjct: 131 TTRNTVCQCEEGTFRE-------EDSPEMCRKC----------RTGCPRGMVKVGDCTPW 173

Query: 169 FYEHGDGCVSCPTPPPSLAGAPWGAVQSAVPLSVAGGRVGVFWVQVLLAGLVVPLLLGAT 228
                   + C       +G   G   +AV L VA     VF  + LL   V+P L G  
Sbjct: 174 ------SDIECVHKE---SGIIIGVTVAAVVLIVA-----VFVCKSLLWKKVLPYLKGIC 219

Query: 229 LTYTYRHCWPHKPLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGN 288
                            D   ++  +  P    + L+   ++L P    E+   VQ    
Sbjct: 220 SGGG------------GDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQ---- 263

Query: 289 SWTPGYPETQEALCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYD-V 347
              P  P     L P  +    + P+ A        L P +  G P   L+   Q +D  
Sbjct: 264 --EPAEPTGVNMLSPGESEHLLE-PAEAERSQRRRLLVPANE-GDPTETLR---QCFDDF 316

Query: 348 MDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRW--RQQQPAGLGAVYAA 405
            D VP   W+  +R LGL + EI+  + E    RD  Y ML +W  +  + A +  +  A
Sbjct: 317 ADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDA 376

Query: 406 LERMG 410
           LE +G
Sbjct: 377 LETLG 381


>gi|4507565 tumor necrosis factor receptor superfamily, member 11a
           precursor [Homo sapiens]
          Length = 616

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 51/173 (29%), Positives = 74/173 (42%), Gaps = 17/173 (9%)

Query: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60
           M  R R    + A LLL  L AR Q   +     C  + H +    CC  C  G Y+ + 
Sbjct: 1   MAPRARRRRPLFALLLLCALLARLQVALQIAP-PCTSEKHYEHLGRCCNKCEPGKYMSSK 59

Query: 61  CTEPCGNSTCLVCPQDTFL-AWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKP 119
           CT    +S CL C  D +L +W  +   +C   + CD   + VA+   ++    RC C  
Sbjct: 60  CT-TTSDSVCLPCGPDEYLDSW--NEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTA 116

Query: 120 G--WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFY 170
           G  W  +C+  +  +     C P L  GA H     L   +DT C  CL G++
Sbjct: 117 GYHWSQDCECCRRNTE----CAPGL--GAQHP----LQLNKDTVCKPCLAGYF 159


>gi|4507587 tumor necrosis factor receptor superfamily, member 7
           precursor [Homo sapiens]
          Length = 260

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 5/92 (5%)

Query: 44  GLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVA 103
           G  CC+ C  G +L   C +    + C  C      + ++H    C  C+ C+   S + 
Sbjct: 36  GKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCN---SGLL 92

Query: 104 LENCSAVADTRCGCKPGWFVECQVSQCVSSSP 135
           + NC+  A+  C C+ GW  +C+  +C    P
Sbjct: 93  VRNCTITANAECACRNGW--QCRDKECTECDP 122


>gi|4505039 lymphotoxin beta receptor [Homo sapiens]
          Length = 435

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 11/100 (11%)

Query: 47  CCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHN--SECARCQACDEQASQVAL 104
           CC  CP G Y+ A C+    ++ C  C ++++     H N  + C  C+ CD       +
Sbjct: 58  CCSRCPPGTYVSAKCSR-IRDTVCATCAENSY---NEHWNYLTICQLCRPCDPVMGLEEI 113

Query: 105 ENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDC 144
             C++   T+C C+PG F      +C      +C+   DC
Sbjct: 114 APCTSKRKTQCRCQPGMFCAAWALECT-----HCELLSDC 148


>gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens]
          Length = 955

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 87/362 (24%), Positives = 122/362 (33%), Gaps = 82/362 (22%)

Query: 23  RAQGGTRSPRCDCAGDFHKKIGL--FCCRGCPAGHYLKAPCT----------------EP 64
           +A G     R DC       I +   CC  C AG      CT                +P
Sbjct: 595 QADGSVSCKRTDCVDSCPHPIRIPGQCCPDCSAG------CTYTGRIFYNNETFPSVLDP 648

Query: 65  CGNSTCLV---------CPQDTFLAWENHHNSECAR-CQACDEQASQVALENCSAVAD-- 112
           C +  CL+         CP      +  H + EC   C+ C+ +  +VA      + D  
Sbjct: 649 CLSCICLLGSVACSPVDCP--ITCTYPFHPDGECCPVCRDCNYEGRKVANGQVFTLDDEP 706

Query: 113 -TRCGCKPGWF----VECQVS---------QCVSSSPFYCQPCLDCGALHRHTRLLCSRR 158
            TRC C+ G      V CQ +          C SS P    P  +   L  H  +  S+ 
Sbjct: 707 CTRCTCQLGEVSCEKVPCQRACADPALLPGDCCSSCPDSLSPLEEKQGLSPHGNVAFSK- 765

Query: 159 DTDCGTCLPGFYEHGDGCVSCPTPPPSLAGAPWGAVQSAVPLSVAGGRVGVFWVQVLLAG 218
               G  L G  E    C SCP PP +    P   V   + L +    +    +    AG
Sbjct: 766 ---AGRSLHGDTEAPVNCSSCPGPPTASPSRP---VLHLLQLLLRTNLMKTQTLPTSPAG 819

Query: 219 LVVPLLLGATLTYTYRHCWPHKPLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSE 278
              P  L   LT T+    P +P   A        + PP     PL S      PP + E
Sbjct: 820 AHGPHSLALGLTATF----PGEP--GASPRLSPGPSTPPGAPTLPLASPGAPQPPPVTPE 873

Query: 279 KICTVQLVGNSWTPGYPETQEALCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMML 338
           +                 +  A   Q+   W  LP   L  A+A ++   SP+ +P  +L
Sbjct: 874 R-----------------SFSASGAQIVSRWPPLPGTLLTEASALSMMDPSPSKTPITLL 916

Query: 339 QP 340
            P
Sbjct: 917 GP 918


>gi|23238204 tumor necrosis factor receptor superfamily, member 19
           isoform 2 precursor [Homo sapiens]
          Length = 417

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 33/113 (29%), Positives = 47/113 (41%), Gaps = 14/113 (12%)

Query: 86  NSECARCQACDEQASQVALENCSAVADTRCGCKPGW-----FVECQVSQCVSSSPFY-CQ 139
           + +C + +  D   + V    C    +    C  G+      V C++ +      F  C+
Sbjct: 31  SGDCRQQEFRDRSGNCVPCNQCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQKCK 90

Query: 140 PCLDCGALHRHTRLLCS-RRDTDCGTCLPGFYE-------HGDGCVSCPTPPP 184
           PCLDC  ++R  +  CS   D  CG CLPGFY            CV C  PPP
Sbjct: 91  PCLDCAVVNRFQKANCSATSDAICGDCLPGFYRKTKLVGFQDMECVPCGDPPP 143


>gi|23238202 tumor necrosis factor receptor superfamily, member 19
           isoform 1 precursor [Homo sapiens]
          Length = 423

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 33/113 (29%), Positives = 47/113 (41%), Gaps = 14/113 (12%)

Query: 86  NSECARCQACDEQASQVALENCSAVADTRCGCKPGW-----FVECQVSQCVSSSPFY-CQ 139
           + +C + +  D   + V    C    +    C  G+      V C++ +      F  C+
Sbjct: 31  SGDCRQQEFRDRSGNCVPCNQCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQKCK 90

Query: 140 PCLDCGALHRHTRLLCS-RRDTDCGTCLPGFYE-------HGDGCVSCPTPPP 184
           PCLDC  ++R  +  CS   D  CG CLPGFY            CV C  PPP
Sbjct: 91  PCLDCAVVNRFQKANCSATSDAICGDCLPGFYRKTKLVGFQDMECVPCGDPPP 143


>gi|4507577 tumor necrosis factor receptor 2 precursor [Homo
           sapiens]
          Length = 461

 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 33/137 (24%), Positives = 53/137 (38%), Gaps = 11/137 (8%)

Query: 38  DFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDE 97
           +++ +    CC  C  G + K  CT+   ++ C  C   T+    N        C +C  
Sbjct: 44  EYYDQTAQMCCSKCSPGQHAKVFCTKT-SDTVCDSCEDSTYTQLWNW----VPECLSCGS 98

Query: 98  QAS--QVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLC 155
           + S  QV  + C+   +  C C+PGW+  C +S+        C P   C       R   
Sbjct: 99  RCSSDQVETQACTREQNRICTCRPGWY--CALSK--QEGCRLCAPLRKCRPGFGVARPGT 154

Query: 156 SRRDTDCGTCLPGFYEH 172
              D  C  C PG + +
Sbjct: 155 ETSDVVCKPCAPGTFSN 171


>gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]
          Length = 277

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 34/129 (26%), Positives = 51/129 (39%), Gaps = 15/129 (11%)

Query: 47  CCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALEN 106
           CC  C  G  L + CTE    + CL C +  FL   N   + C + + CD        + 
Sbjct: 37  CCSLCQPGQKLVSDCTE-FTETECLPCGESEFLDTWNRE-THCHQHKYCDPNLGLRVQQK 94

Query: 107 CSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCL---DCGALHRHTRLLCSRRDTDCG 163
            ++  DT C C+ GW        C S +   C+ C+    C       ++     DT C 
Sbjct: 95  GTSETDTICTCEEGW-------HCTSEA---CESCVLHRSCSPGFGVKQIATGVSDTICE 144

Query: 164 TCLPGFYEH 172
            C  GF+ +
Sbjct: 145 PCPVGFFSN 153


>gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]
          Length = 203

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 34/129 (26%), Positives = 51/129 (39%), Gaps = 15/129 (11%)

Query: 47  CCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALEN 106
           CC  C  G  L + CTE    + CL C +  FL   N   + C + + CD        + 
Sbjct: 37  CCSLCQPGQKLVSDCTE-FTETECLPCGESEFLDTWNRE-THCHQHKYCDPNLGLRVQQK 94

Query: 107 CSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCL---DCGALHRHTRLLCSRRDTDCG 163
            ++  DT C C+ GW        C S +   C+ C+    C       ++     DT C 
Sbjct: 95  GTSETDTICTCEEGW-------HCTSEA---CESCVLHRSCSPGFGVKQIATGVSDTICE 144

Query: 164 TCLPGFYEH 172
            C  GF+ +
Sbjct: 145 PCPVGFFSN 153


>gi|7657039 tumor necrosis factor receptor superfamily, member 21
           precursor [Homo sapiens]
          Length = 655

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 25/77 (32%), Positives = 32/77 (41%), Gaps = 7/77 (9%)

Query: 48  CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALEN- 106
           C  CPAG Y+   CT       C  CP  TF      H +   +C  C +      +E  
Sbjct: 67  CDKCPAGTYVSEHCTNT-SLRVCSSCPVGTF----TRHENGIEKCHDCSQPCPWPMIEKL 121

Query: 107 -CSAVADTRCGCKPGWF 122
            C+A+ D  C C PG F
Sbjct: 122 PCAALTDRECTCPPGMF 138


>gi|148743793 osteoprotegerin precursor [Homo sapiens]
          Length = 401

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 34/126 (26%), Positives = 48/126 (38%), Gaps = 15/126 (11%)

Query: 48  CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQ-ACDEQASQVALEN 106
           C  CP G YLK  CT     + C  CP D +     H + EC  C   C E   Q   + 
Sbjct: 41  CDKCPPGTYLKQHCTAK-WKTVCAPCP-DHYYTDSWHTSDECLYCSPVCKE--LQYVKQE 96

Query: 107 CSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCL 166
           C+   +  C CK G ++E +          +C     C       +     R+T C  C 
Sbjct: 97  CNRTHNRVCECKEGRYLEIE----------FCLKHRSCPPGFGVVQAGTPERNTVCKRCP 146

Query: 167 PGFYEH 172
            GF+ +
Sbjct: 147 DGFFSN 152


>gi|21361086 tumor necrosis factor receptor superfamily, member 10a
           [Homo sapiens]
          Length = 468

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 82/304 (26%), Positives = 112/304 (36%), Gaps = 52/304 (17%)

Query: 132 SSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDG---CVSCPTPPPS--- 185
           S++ F C PC  C +         + R+T C  C PG + + +    C  C    P    
Sbjct: 158 SNNLFACLPCTACKSDEEERSPCTTTRNTAC-QCKPGTFRNDNSAEMCRKCSRGCPRGMV 216

Query: 186 --LAGAPWGAVQSAVPLSVAGGRVGVFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLV 243
                 PW  ++     S  G  +   WV +L+  LVVPLLL A L      C       
Sbjct: 217 KVKDCTPWSDIECVHKESGNGHNI---WV-ILVVTLVVPLLLVAVLIV----CCCIGSGC 268

Query: 244 TADEAGME--------ALTPPPATHLSPLDSAHT-LLAPPDSSEKICTVQLVGNSWTPGY 294
             D   M+         L  P A      D+AH  +L+  DS     + Q +        
Sbjct: 269 GGDPKCMDRVCFWRLGLLRGPGAE-----DNAHNEILSNADSLSTFVSEQQM-------- 315

Query: 295 PETQEALCPQVTWSWDQLPSRA---LGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMD-- 349
            E+QE     +T    Q P  A   LGPA A   S       PA    P   L    D  
Sbjct: 316 -ESQEP--ADLTGVTVQSPGEAQCLLGPAEAEG-SQRRRLLVPANGADPTETLMLFFDKF 371

Query: 350 --AVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRW--RQQQPAGLGAVYAA 405
              VP   W + +R L L + EI+ V        D  Y ML +W  +  + A +  +  A
Sbjct: 372 ANIVPFDSWDQLMRQLDLTKNEIDVVRAGTAGPGDALYAMLMKWVNKTGRNASIHTLLDA 431

Query: 406 LERM 409
           LERM
Sbjct: 432 LERM 435


>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
          Length = 1044

 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 56/193 (29%), Positives = 68/193 (35%), Gaps = 58/193 (30%)

Query: 26  GGTRSP---RCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPC------------GNSTC 70
           GGT SP    C C   +    GL C   CP+G +    C E C            G+ +C
Sbjct: 455 GGTCSPVDGSCTCKEGWQ---GLDCTLPCPSGTW-GLNCNESCTCANGAACSPIDGSCSC 510

Query: 71  ----------LVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVAD---TRCG- 116
                     L CP  TF    + H  +C+    CD         +C  +A     RC  
Sbjct: 511 TPGWLGDTCELPCPDGTFGLNCSEH-CDCSHADGCDPVTG-----HCCCLAGWTGIRCDS 564

Query: 117 -CKPG-WFVECQVSQCVSSSPFYCQP---CLDCGALHRHTRLLCSRRDTDCGTCLPGFYE 171
            C PG W   C VS C   +   C P     +C    R    LC R       C PGFY 
Sbjct: 565 TCPPGRWGPNCSVS-CSCENGGSCSPEDGSCECAPGFRGP--LCQR------ICPPGFYG 615

Query: 172 HGDGCVSCPTPPP 184
           HG     C  P P
Sbjct: 616 HG-----CAQPCP 623



 Score = 33.9 bits (76), Expect = 0.29
 Identities = 47/177 (26%), Positives = 56/177 (31%), Gaps = 49/177 (27%)

Query: 33  CDCAGDFHKKIGLFCCRGCPAGHYLK-----------APCTEPCGNSTC----------L 71
           C CA  F   +G  C   C AG Y               C+   G+ TC          L
Sbjct: 422 CTCAPGF---MGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTL 478

Query: 72  VCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCV 131
            CP  T   W  + N  C     C   A+      CS + D  C C PGW  +     C 
Sbjct: 479 PCPSGT---WGLNCNESCT----CANGAA------CSPI-DGSCSCTPGWLGDTCELPCP 524

Query: 132 S-------SSPFYCQPCLDCGALHRHTRLLCSRRDTDC-GTCLPGFYEHGDGC-VSC 179
                   S    C     C  +  H   L       C  TC PG +  G  C VSC
Sbjct: 525 DGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRW--GPNCSVSC 579



 Score = 29.3 bits (64), Expect = 7.1
 Identities = 43/167 (25%), Positives = 59/167 (35%), Gaps = 40/167 (23%)

Query: 24  AQGGTRSP---RCDCAGDFHKKIGLFCCRGCPAGH-----------YLKAPCTEPCGNST 69
           A  GT SP    C C   F   IG  C + CP G            +  A C+   G   
Sbjct: 670 ANNGTCSPIDGSCQC---FPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACH 726

Query: 70  C------LVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFV 123
           C      L C Q    A+      +C R   C   AS      C  ++  +C C+ G+  
Sbjct: 727 CTPGWTGLFCTQRCPAAF---FGKDCGRVCQCQNGAS------CDHISG-KCTCRTGFTG 776

Query: 124 ECQVSQCVSSSPFY-CQPCLDCGALHRHTRLLCSRRDTDCGTCLPGF 169
           +    +C   +  Y CQ   +C  ++  T   C      C  C PGF
Sbjct: 777 QHCEQRCAPGTFGYGCQQLCEC--MNNST---CDHVTGTC-YCSPGF 817


>gi|4507579 tumor necrosis factor receptor superfamily, member 4
           precursor [Homo sapiens]
          Length = 277

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 43/176 (24%), Positives = 62/176 (35%), Gaps = 38/176 (21%)

Query: 13  AALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLV 72
           AALLL+ LG     G       C GD +      CC  C  G+ + + C+    N+ C  
Sbjct: 14  AALLLLGLGLSTVTGLH-----CVGDTYPSNDR-CCHECRPGNGMVSRCSRS-QNTVCRP 66

Query: 73  CPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVS 132
           C    +   +   +  C  C  C+ ++     + C+A  DT C C+ G            
Sbjct: 67  CGPGFYN--DVVSSKPCKPCTWCNLRSGSERKQLCTATQDTVCRCRAG------------ 112

Query: 133 SSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTPPPSLAG 188
                 QP            L   +   DC  C PG +  GD     P    +LAG
Sbjct: 113 -----TQP------------LDSYKPGVDCAPCPPGHFSPGDNQACKPWTNCTLAG 151


>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
          Length = 2663

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 64/221 (28%), Positives = 81/221 (36%), Gaps = 54/221 (24%)

Query: 165  CL-PGFYEHGDGCVSCPTPPPSLAGAPWGAVQSAVPLSVAGGRVGVFWVQVLL------A 217
            CL PG+Y    G    P+P       P  AV +  P        GVF            A
Sbjct: 1845 CLSPGYYSPDYGL---PSPKVDALHCPPAAVVTVTP-----SPEGVFSSLQAKPSPSPRA 1896

Query: 218  GLVVPLLLGATLTYTYRHCWPHKPLVTADEAGMEALTPPPATHLSPLD----SAHTLLAP 273
             L+VP L GA          P     + D+    A+ PP  ++L PLD    SA     P
Sbjct: 1897 ELLVPSLEGAL---------PPDLDTSEDQQATAAIIPPEPSYLEPLDEGPFSAVITEEP 1947

Query: 274  PD---SSEKICTVQLVGN------SWTPG----------YPETQEALCPQVTWSWDQLPS 314
             +    SE+     L+G       SW  G          +PE+ +  CP      D L S
Sbjct: 1948 VEWAHPSEQALASSLIGGTSENPVSWPVGSDLLLKSPQRFPESPKRFCPA-----DPLHS 2002

Query: 315  RALGPAAAPTLSPESPAGSPAMMLQP--GPQLYDVMDAVPA 353
             A GP +A      +P  SPA    P   P L DV D V A
Sbjct: 2003 AAPGPFSASEAPYPAPPASPAPYALPVAEPGLEDVKDGVDA 2043


>gi|14790170 tumor necrosis factor receptor superfamily, member 6b
           [Homo sapiens]
          Length = 300

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 52/214 (24%), Positives = 71/214 (33%), Gaps = 50/214 (23%)

Query: 48  CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQA-CDEQASQVALEN 106
           C  CP G +++ PC      +TC  CP   +  + N +   C  C   C E+  +     
Sbjct: 49  CAQCPPGTFVQRPCRRD-SPTTCGPCPPRHYTQFWN-YLERCRYCNVLCGEREEEA--RA 104

Query: 107 CSAVADTRCGCKPGWFVEC----------------------QVSQC----------VSSS 134
           C A  +  C C+ G+F                         Q +QC           SSS
Sbjct: 105 CHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSS 164

Query: 135 PFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTPPPSLAGAPWGAV 194
              CQP  +C AL                  +PG   H   C SC   P S         
Sbjct: 165 SEQCQPHRNCTAL-------------GLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEEC 211

Query: 195 QSAVPLSVAGGRVGVFWVQVLLAGLVVPLLLGAT 228
           + AV   VA   + +  +Q LL  L  P   G T
Sbjct: 212 ERAVIDFVAFQDISIKRLQRLLQALEAPEGWGPT 245


>gi|4507585 tumor necrosis factor receptor superfamily, member 6b
           [Homo sapiens]
          Length = 300

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 52/214 (24%), Positives = 71/214 (33%), Gaps = 50/214 (23%)

Query: 48  CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQA-CDEQASQVALEN 106
           C  CP G +++ PC      +TC  CP   +  + N +   C  C   C E+  +     
Sbjct: 49  CAQCPPGTFVQRPCRRD-SPTTCGPCPPRHYTQFWN-YLERCRYCNVLCGEREEEA--RA 104

Query: 107 CSAVADTRCGCKPGWFVEC----------------------QVSQC----------VSSS 134
           C A  +  C C+ G+F                         Q +QC           SSS
Sbjct: 105 CHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSS 164

Query: 135 PFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTPPPSLAGAPWGAV 194
              CQP  +C AL                  +PG   H   C SC   P S         
Sbjct: 165 SEQCQPHRNCTAL-------------GLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEEC 211

Query: 195 QSAVPLSVAGGRVGVFWVQVLLAGLVVPLLLGAT 228
           + AV   VA   + +  +Q LL  L  P   G T
Sbjct: 212 ERAVIDFVAFQDISIKRLQRLLQALEAPEGWGPT 245


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.462 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,267,210
Number of Sequences: 37866
Number of extensions: 1203832
Number of successful extensions: 5499
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 219
Number of HSP's that attempted gapping in prelim test: 5139
Number of HSP's gapped (non-prelim): 560
length of query: 426
length of database: 18,247,518
effective HSP length: 105
effective length of query: 321
effective length of database: 14,271,588
effective search space: 4581179748
effective search space used: 4581179748
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.