Guide to the Human Genome
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Search of human proteins with 115392133

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]
         (1714 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]             3600   0.0  
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]             1393   0.0  
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   994   0.0  
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   994   0.0  
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     955   0.0  
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      946   0.0  
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     945   0.0  
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]      924   0.0  
gi|48762934 alpha 2 type I collagen [Homo sapiens]                    907   0.0  
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]   896   0.0  
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...   895   0.0  
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...   895   0.0  
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...   895   0.0  
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   883   0.0  
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   883   0.0  
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   883   0.0  
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   813   0.0  
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   811   0.0  
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   806   0.0  
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]    805   0.0  
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         785   0.0  
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]               782   0.0  
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]        773   0.0  
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...   767   0.0  
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...   767   0.0  
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...   767   0.0  
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...   767   0.0  
gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens]    736   0.0  
gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ...   734   0.0  
gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo s...   734   0.0  

>gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]
          Length = 1714

 Score = 3600 bits (9336), Expect = 0.0
 Identities = 1714/1714 (100%), Positives = 1714/1714 (100%)

Query: 1    MHLRAHRTRRGKVSPTAKTKSLLHFIVLCVAGVVVHAQEQGIDILHQLGLGGKDVRHSSP 60
            MHLRAHRTRRGKVSPTAKTKSLLHFIVLCVAGVVVHAQEQGIDILHQLGLGGKDVRHSSP
Sbjct: 1    MHLRAHRTRRGKVSPTAKTKSLLHFIVLCVAGVVVHAQEQGIDILHQLGLGGKDVRHSSP 60

Query: 61   ATAVPSASTPLPQGVHLTESGVIFKNDAYIETPFVKILPVNLGQPFTILTGLQSHRVNNA 120
            ATAVPSASTPLPQGVHLTESGVIFKNDAYIETPFVKILPVNLGQPFTILTGLQSHRVNNA
Sbjct: 61   ATAVPSASTPLPQGVHLTESGVIFKNDAYIETPFVKILPVNLGQPFTILTGLQSHRVNNA 120

Query: 121  FLFSIRNKNRLQLGVQLLPKKLVVHIRGKQPAVFNYSVHDEQWHSFAITIRNQSVSMFVE 180
            FLFSIRNKNRLQLGVQLLPKKLVVHIRGKQPAVFNYSVHDEQWHSFAITIRNQSVSMFVE
Sbjct: 121  FLFSIRNKNRLQLGVQLLPKKLVVHIRGKQPAVFNYSVHDEQWHSFAITIRNQSVSMFVE 180

Query: 181  CGKKYFSTETIPEVQTFDSNSVFTLGSMNNNSIHFEGIVCQLDIIPSAEASADYCRYVKQ 240
            CGKKYFSTETIPEVQTFDSNSVFTLGSMNNNSIHFEGIVCQLDIIPSAEASADYCRYVKQ
Sbjct: 181  CGKKYFSTETIPEVQTFDSNSVFTLGSMNNNSIHFEGIVCQLDIIPSAEASADYCRYVKQ 240

Query: 241  QCRQADKYQPETSIPCTTLIPTKIPEHSPPPKLFAEKVLSEDTFTEGKSIPNIIKNDSET 300
            QCRQADKYQPETSIPCTTLIPTKIPEHSPPPKLFAEKVLSEDTFTEGKSIPNIIKNDSET
Sbjct: 241  QCRQADKYQPETSIPCTTLIPTKIPEHSPPPKLFAEKVLSEDTFTEGKSIPNIIKNDSET 300

Query: 301  VYKRQEHQISRSQLSSLQSGNVSAVDLTNHGIQAKEMITEEDTQTNFSLSVTTHRISEAK 360
            VYKRQEHQISRSQLSSLQSGNVSAVDLTNHGIQAKEMITEEDTQTNFSLSVTTHRISEAK
Sbjct: 301  VYKRQEHQISRSQLSSLQSGNVSAVDLTNHGIQAKEMITEEDTQTNFSLSVTTHRISEAK 360

Query: 361  MNTKEKFSSLLNMSDNITQHDDRVTGLSLFKKMPSILPQIKQDTITNLKKAITANLHTNE 420
            MNTKEKFSSLLNMSDNITQHDDRVTGLSLFKKMPSILPQIKQDTITNLKKAITANLHTNE
Sbjct: 361  MNTKEKFSSLLNMSDNITQHDDRVTGLSLFKKMPSILPQIKQDTITNLKKAITANLHTNE 420

Query: 421  LMEMQPILNTSLHRVTNEPSVDNHLDLRKEGEFYPDATYPIENSYETELYDYYYYEDLNT 480
            LMEMQPILNTSLHRVTNEPSVDNHLDLRKEGEFYPDATYPIENSYETELYDYYYYEDLNT
Sbjct: 421  LMEMQPILNTSLHRVTNEPSVDNHLDLRKEGEFYPDATYPIENSYETELYDYYYYEDLNT 480

Query: 481  MLEMEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPG 540
            MLEMEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPG
Sbjct: 481  MLEMEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPG 540

Query: 541  FSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPG 600
            FSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPG
Sbjct: 541  FSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPG 600

Query: 601  RQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRG 660
            RQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRG
Sbjct: 601  RQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRG 660

Query: 661  PAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQG 720
            PAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQG
Sbjct: 661  PAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQG 720

Query: 721  TAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPG 780
            TAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPG
Sbjct: 721  TAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPG 780

Query: 781  QNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKG 840
            QNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKG
Sbjct: 781  QNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKG 840

Query: 841  EVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPG 900
            EVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPG
Sbjct: 841  EVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPG 900

Query: 901  PIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIG 960
            PIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIG
Sbjct: 901  PIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIG 960

Query: 961  KTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESG 1020
            KTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESG
Sbjct: 961  KTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESG 1020

Query: 1021 LQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKG 1080
            LQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKG
Sbjct: 1021 LQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKG 1080

Query: 1081 EMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIG 1140
            EMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIG
Sbjct: 1081 EMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIG 1140

Query: 1141 KSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVL 1200
            KSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVL
Sbjct: 1141 KSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVL 1200

Query: 1201 GPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGER 1260
            GPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGER
Sbjct: 1201 GPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGER 1260

Query: 1261 GSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIR 1320
            GSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIR
Sbjct: 1261 GSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIR 1320

Query: 1321 GGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPC 1380
            GGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPC
Sbjct: 1321 GGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPC 1380

Query: 1381 GDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGII 1440
            GDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGII
Sbjct: 1381 GDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGII 1440

Query: 1441 GPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQMDINAAIQALIESNTALQM 1500
            GPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQMDINAAIQALIESNTALQM
Sbjct: 1441 GPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQMDINAAIQALIESNTALQM 1500

Query: 1501 ESYQNTEVTLIDHSEEIFKTLNYLSNLLHSIKNPLGTRDNPARICKDLLNCEQKVSDGKY 1560
            ESYQNTEVTLIDHSEEIFKTLNYLSNLLHSIKNPLGTRDNPARICKDLLNCEQKVSDGKY
Sbjct: 1501 ESYQNTEVTLIDHSEEIFKTLNYLSNLLHSIKNPLGTRDNPARICKDLLNCEQKVSDGKY 1560

Query: 1561 WIDPNLGCPSDAIEVFCNFSAGGQTCLPPVSVTKLEFGVGKVQMNFLHLLSSEATHIITI 1620
            WIDPNLGCPSDAIEVFCNFSAGGQTCLPPVSVTKLEFGVGKVQMNFLHLLSSEATHIITI
Sbjct: 1561 WIDPNLGCPSDAIEVFCNFSAGGQTCLPPVSVTKLEFGVGKVQMNFLHLLSSEATHIITI 1620

Query: 1621 HCLNTPRWTSTQTSGPGLPIGFKGWNGQIFKVNTLLEPKVLSDDCKIQDGSWHKATFLFH 1680
            HCLNTPRWTSTQTSGPGLPIGFKGWNGQIFKVNTLLEPKVLSDDCKIQDGSWHKATFLFH
Sbjct: 1621 HCLNTPRWTSTQTSGPGLPIGFKGWNGQIFKVNTLLEPKVLSDDCKIQDGSWHKATFLFH 1680

Query: 1681 TQEPNQLPVIEVQKLPHLKTERKYYIDSSSVCFL 1714
            TQEPNQLPVIEVQKLPHLKTERKYYIDSSSVCFL
Sbjct: 1681 TQEPNQLPVIEVQKLPHLKTERKYYIDSSSVCFL 1714


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score = 1393 bits (3605), Expect = 0.0
 Identities = 694/1236 (56%), Positives = 822/1236 (66%), Gaps = 13/1236 (1%)

Query: 489  GPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVP 548
            GPKGD G PGPPG  G+PG  G RGPRG PGP+GNPGLPG PG KG KGDPG SPG+   
Sbjct: 628  GPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHD 687

Query: 549  GEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPE 608
            G KGD GL GL G PG  G KG KG+PG  G PGEQG PG  G+ G+ GYPGRQGL GP 
Sbjct: 688  GAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPV 747

Query: 609  GNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSP 668
            G+PGPKG++G+IG PG  G  G +GERG+PG+ GK+G  G  GFPG FG+RGP GLDG+P
Sbjct: 748  GDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNP 807

Query: 669  GLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEP 728
            G +G  GPPG PGL G +G +GPIG  G  G  GL G+ G PG+KGDKGEQG  G  G+P
Sbjct: 808  GELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDP 867

Query: 729  GYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPK 788
            G+ GDKG+ GLPG PG RGK GP G+ GD G  G  GPPGPEGFPGDIG PG NGPEG K
Sbjct: 868  GFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMK 927

Query: 789  GLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNI 848
            G  G RG PGP G  G +G+EGP+G  G  G  G+PG+KG+ G PG +G+KGE GD G  
Sbjct: 928  GKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRP 987

Query: 849  GKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLP 908
            G +GE G +G  G VG  G +GEKG+RG  GP G  G KG MG+PG PG  G  G  G  
Sbjct: 988  GPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQ 1047

Query: 909  GHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGER 968
            G  G+RGPPG +G KG+RG RGPDG  GEQG +G KG  G QG+ G  G  G  G  G  
Sbjct: 1048 GPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHL 1107

Query: 969  GFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAK 1028
            G +G PG+ G  G  G +GLPGEPG +G QG +GPPGEMG +GPPG  GE GL GE G K
Sbjct: 1108 GSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMK 1167

Query: 1029 GDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGII 1088
            GD+G  G+ G  G  G RGEPG  G+ G  G DGLKG  G  G  GE GEKG+ GL G  
Sbjct: 1168 GDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGED 1227

Query: 1089 GPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGAR 1148
            GP G  G TG+ GPEG  G  G++GR G KG KG  G  GE+G  G PG  G  GPKG+R
Sbjct: 1228 GPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSR 1287

Query: 1149 GTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGE 1208
            G+ G  G  G MG  GEPG+ GY GH+G  GP G PGPKGEKG  GED    GPPGP G+
Sbjct: 1288 GSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGD 1347

Query: 1209 PGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGK 1268
             GPVGD+G+RGEPG  GY G  GV GLRG  GQQG PG PG +G  G KG +G+EG KGK
Sbjct: 1348 RGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGK 1407

Query: 1269 KGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGN---PGKIGPPGKQGLPGIRGGPGR 1325
            +G  G  G+ G+ GLQGL GP+G+ G  G +GI+G    PG+ G  G+QG  G  G PG 
Sbjct: 1408 QGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGP 1467

Query: 1326 TGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGL 1385
             G AG  G PGV   +GLPG+ G  G KGE GLPGQ G  GKRG  G  G  G  G+PG 
Sbjct: 1468 MGPAGKRGNPGV---AGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGS 1524

Query: 1386 KGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGR 1445
            KGQPG+ G  G  G  G  GPKGP GD G  GI GP+GP G  G  G +G  GI+GP+G 
Sbjct: 1525 KGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGL 1584

Query: 1446 TGPRGEKGFRGE------TGPQGPRGQPGPPGPPGAPGPRKQMDINAAIQALIESNTALQ 1499
             GP+G+KG RG+       GP GPRG+PGPPGPPG P   +Q D+ AA Q  ++++ AL+
Sbjct: 1585 PGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGPIQLQQDDLGAAFQTWMDTSGALR 1644

Query: 1500 MESYQNTEVTLIDHSEEIFKTLNYLSNLLHSIKNPLGTRDNPARICKDLLNCEQKVSDGK 1559
             ESY   +  ++D   EIFKTL+YLSNL+ SIK PLGT++NPAR+C+DL++CEQK+ DG 
Sbjct: 1645 PESYSYPDRLVLDQGGEIFKTLHYLSNLIQSIKTPLGTKENPARVCRDLMDCEQKMVDGT 1704

Query: 1560 YWIDPNLGCPSDAIEVFCNFSAGGQTCLPPVSVTKLEFGVGKVQMNFLHLLSSEATHIIT 1619
            YW+DPNLGC SD IEV CNF+ GGQTCL P++ +K+EF + +VQMNFLHLLSSE T  IT
Sbjct: 1705 YWVDPNLGCSSDTIEVSCNFTHGGQTCLKPITASKVEFAISRVQMNFLHLLSSEVTQHIT 1764

Query: 1620 IHCLNTPRWTSTQTSGPG-LPIGFKGWNGQIFKVNTLLEPKVLSDDCKIQDGSWHKATFL 1678
            IHCLN   W       P    + F+ WNGQIF+      P+V  D CK+QDG WH+  F 
Sbjct: 1765 IHCLNMTVWQEGTGQTPAKQAVRFRAWNGQIFEAGGQFRPEVSMDGCKVQDGRWHQTLFT 1824

Query: 1679 FHTQEPNQLPVIEVQKLPHLKTERKYYIDSSSVCFL 1714
            F TQ+P QLP+I V  LP   + ++Y ++    CFL
Sbjct: 1825 FRTQDPQQLPIISVDNLPPASSGKQYRLEVGPACFL 1860



 Score =  717 bits (1850), Expect = 0.0
 Identities = 424/968 (43%), Positives = 510/968 (52%), Gaps = 113/968 (11%)

Query: 487  LRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPK---GPKGDPGFSP 543
            L G  G+ GPPG  G  G PGP+G  G +G PGP G+PG  G PG +   GP GDPG   
Sbjct: 695  LPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPG--- 751

Query: 544  GQPVPGEKGDQGLSGLMGPPGMQGDKGL---------KGHPGLPGLPGEQGIPGFAGN-- 592
                 G +G  GL GL G PG  G++GL          G PG PG+ GE+G PG  GN  
Sbjct: 752  ---PKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPG 808

Query: 593  -IGSPGYPGRQGL------AGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKG 645
             +G PG PG  GL       GP G PGPKG +G +GS GE G  G +GE+G+PG+ G  G
Sbjct: 809  ELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPG 868

Query: 646  FKGRQ------GFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPG 699
            F+G +      GFPG  G  GP G  G  G +G  GPPG  G  G +GP G  GP G+ G
Sbjct: 869  FQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKG 928

Query: 700  PMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPG 759
                 G +GLPG +G  G +G  G +G PG PG +G  G  G PG  G  G  G+ GDPG
Sbjct: 929  K---PGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPG 985

Query: 760  LQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELG 819
              GP G  G  GF G +G PG  G +G +G++G  G PGP G  G  G  G +G  GE G
Sbjct: 986  RPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPG 1045

Query: 820  P------RGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEK- 872
            P      RG PG +G  G  GP G  G  G+QG+ G  G  GP G PG  G  G  GE+ 
Sbjct: 1046 PQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERG 1105

Query: 873  --GERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGS------QGPKG 924
              G RG PG  GP G  G  G PG PG  GP GP+G PG +G +GPPG+       G  G
Sbjct: 1106 HLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAG 1165

Query: 925  QRGSRGPDGLLGEQGIQGAKGE---KGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPG 981
             +G  GP G  GEQG+ G +GE   +GD G  GP GL G  G+PG  G  G+ G +GL G
Sbjct: 1166 MKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMG 1225

Query: 982  STGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTE------GESGLQGEPGAKGDVGTAG 1035
              G  G PG  G+RG +G  G  GE G  G  G +      GE G+ G+PG  G  G  G
Sbjct: 1226 EDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKG 1285

Query: 1036 SVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEM----------GLP 1085
            S G  G  G  G  GA GE GL G DG KG+ G  G PG  GEKGE           G P
Sbjct: 1286 SRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPP 1345

Query: 1086 GIIGPL------GRSGQTGLPGPEGIVGI---PGQRGRPGKKGDKGQIGPTGEVGSRGPP 1136
            G  GP+      G  G  G PG EG+ G+   PGQ+G+PG  G +G  GP G  G+ GP 
Sbjct: 1346 GDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPK 1405

Query: 1137 GKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGED 1196
            GK GK+G  G RG +      GL G  G  G+ G +G +G  GP GLPG  G+ G  GE 
Sbjct: 1406 GKQGKAGAPGRRGVQ------GLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQ 1459

Query: 1197 STVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGL 1256
                   G  G+PGP+G  G+RG PG  G  G  G PG +G +G  G  G PG +G +G 
Sbjct: 1460 -------GDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGR 1512

Query: 1257 KGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGL 1316
             G  G++G  G KG PG SG+ G PG+ GL GPK            G PG I   G +G+
Sbjct: 1513 TGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPK------------GPPGDI---GFKGI 1557

Query: 1317 PGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGD 1376
             G RG PG  G  G  GP G+ G SGLP      GPKG++G  G  G+QG RG  G +G 
Sbjct: 1558 QGPRGPPGLMGKEGIVGPLGILGPSGLP------GPKGDKGSRGDWGLQGPRGPPGPRGR 1611

Query: 1377 QGPCGDPG 1384
             GP G PG
Sbjct: 1612 PGPPGPPG 1619



 Score =  152 bits (385), Expect = 2e-36
 Identities = 88/197 (44%), Positives = 104/197 (52%), Gaps = 12/197 (6%)

Query: 484  MEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSP 543
            +E + GP G  G  G  G  G  G  G  GP G  G  GNPG+ GLPG +GP        
Sbjct: 1437 LEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGP-------- 1488

Query: 544  GQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQG 603
                PG KG+ GL G +GPPG +G +G  G PG  G PG +G PG +G +G PG  G  G
Sbjct: 1489 ----PGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFG 1544

Query: 604  LAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAG 663
              GP G+ G KG QG  G PG  G+ G  G  GI G  G  G KG +G  GD+G +GP G
Sbjct: 1545 PKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRG 1604

Query: 664  LDGSPGLVGGTGPPGFP 680
              G  G  G  GPPG P
Sbjct: 1605 PPGPRGRPGPPGPPGGP 1621



 Score =  144 bits (362), Expect = 1e-33
 Identities = 76/217 (35%), Positives = 120/217 (55%), Gaps = 24/217 (11%)

Query: 40  QGIDILHQLGLGGKDVRHSSPATAVPSASTPLPQGVHLTESGVIFKNDAYIETPFVKILP 99
           + +DIL +LGL                A +P P GV   +SG IF   A ++ P   ++P
Sbjct: 44  EDVDILQRLGLSWT------------KAGSPAPPGVIPFQSGFIFTQRARLQAPTGTVIP 91

Query: 100 VNLGQPFTILTGLQSHRVNNAFLFSIRN-KNRLQLGVQLLPKKLVVHIRGKQPAVFNYSV 158
             LG    ++  L SHRVN+AFLF++R+ K +LQLG+Q LP K VVH+  ++   F+  +
Sbjct: 92  AALGTELALVLSLCSHRVNHAFLFAVRSQKRKLQLGLQFLPGKTVVHLGSRRSVAFDLDM 151

Query: 159 HDEQWHSFAITIRNQSVSMFVECGKKYFSTETIPEVQTF------DSNSVFTLGSMNNNS 212
           HD +WH  A+ +R ++V++   CG++      +P +  F      D    F  G MN ++
Sbjct: 152 HDGRWHHLALELRGRTVTLVTACGQR-----RVPVLLPFHRDPALDPGGSFLFGKMNPHA 206

Query: 213 IHFEGIVCQLDIIPSAEASADYCRYVKQQCRQADKYQ 249
           + FEG +CQ  I P  + + +YC ++++QC QAD YQ
Sbjct: 207 VQFEGALCQFSIYPVTQVAHNYCTHLRKQCGQADTYQ 243



 Score =  114 bits (284), Expect = 1e-24
 Identities = 75/170 (44%), Positives = 90/170 (52%), Gaps = 29/170 (17%)

Query: 488  RGPKGDTGPPGPPGPAGI---PGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKG------- 537
            +G +GD G PGP GPAG    PG +G  G +G PG  G  GLPG  GP G +G       
Sbjct: 1456 QGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGL 1515

Query: 538  -----DPGFSPGQPVP-GEKGDQGLSGLMGPPGMQGD---KGLKGHPGLPGLPGEQGIPG 588
                 +PG S GQP   GE G  G++GL GP G  GD   KG++G  G PGL G++GI G
Sbjct: 1516 PGNQGEPG-SKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVG 1574

Query: 589  FAGNIGSPGYPGRQG---------LAGPEGNPGPKGAQGFIGSPGEAGQL 629
              G +G  G PG +G         L GP G PGP+G  G  G PG   QL
Sbjct: 1575 PLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGPIQL 1624



 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 28/59 (47%), Positives = 32/59 (54%), Gaps = 3/59 (5%)

Query: 481  MLEMEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDP 539
            ++  E + GP G  GP G PGP    G  G RG  G+ GP G PG  G PGP GP G P
Sbjct: 1566 LMGKEGIVGPLGILGPSGLPGP---KGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGP 1621


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score =  994 bits (2570), Expect = 0.0
 Identities = 577/1342 (42%), Positives = 692/1342 (51%), Gaps = 126/1342 (9%)

Query: 489  GPKGDTGPPGPPGPAGIPGPSGK---------------------RGPRGIPGPHGNPGLP 527
            G  G+ GPPGPPGP G PG  G                      +GP G  GP G PG  
Sbjct: 156  GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 215

Query: 528  GLPGPKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLP---GLPGEQ 584
            G PGP+G +G+PG  PG+  PG  G  G  G  GPPG  GD G  G PG     G PG Q
Sbjct: 216  GAPGPQGFQGNPG-EPGE--PGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 272

Query: 585  GIPGFAGNIGSPGYPGRQ---GLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIR 641
            G  GF G  G PG  G +   GL G +G  G  G +G  GSPGE G  GP G RG+PG R
Sbjct: 273  GARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGER 332

Query: 642  GKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGI---- 697
            G+ G  G  G  G+ G  GPAG  G  G  GG G PG PG +G  GP G  GP G     
Sbjct: 333  GRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPR 392

Query: 698  --------PGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKS 749
                    PGP G SGN G  GI G KG  G  G  G PG+PG +G    PGP G  G  
Sbjct: 393  GEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP---PGPQGATGPL 449

Query: 750  GPSGQTGDPGL------QGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLK 803
            GP GQTG+PG+      QGP G PGP G  G  G  G+ G  G +G  G  GP GPPG +
Sbjct: 450  GPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGER 509

Query: 804  GTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGE- 862
            G  G  G  G  G  GP+G PG++G +G  GP+G  G+ G  G  G  G  G  G PG+ 
Sbjct: 510  GAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDA 569

Query: 863  -----VGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGV---PGPIGPLGLPGHVGAR 914
                 VG +G+ GE G  G PGP G +G+ GVMG+PGP G    PG  G  GLPG  G R
Sbjct: 570  GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLR 629

Query: 915  GPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKP 974
            G PG  G  G  G  GP G  GE+G QGA G  G QG  GP G  G+ G PG++G  G+ 
Sbjct: 630  GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA 689

Query: 975  GLQGLPGSTGDRGLPGE---PGLRGLQGDVGPPGEMGME---------GPPGTEGESGLQ 1022
            G  GL G  G+RG PGE   PG +GLQG  G PG  G +         GPPG +G  GLQ
Sbjct: 690  GAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQ 749

Query: 1023 GEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGE---K 1079
            G PG +G  G AG  G  G+ G +G  GAPG++G +G  G  G PG  G  GE GE    
Sbjct: 750  GMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPP 809

Query: 1080 GEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKI 1139
            G  G  G  G  G  G+TG PGP G  G PG  G+PG KG++G+ G  G+ G+ GP G  
Sbjct: 810  GPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPS 869

Query: 1140 GKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTV 1199
            G  GP+G  G  G  G  G  GP G  G PG  G  G PG +G PGP G  G  G+D   
Sbjct: 870  GAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPK 929

Query: 1200 -----LGPPGPRGEP---GPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQ 1251
                  GPPG  GEP   GP G  GE+GEPG +G  G  G PG +G  GQ+G  G PG +
Sbjct: 930  GARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQR 989

Query: 1252 GEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPP 1311
            GE+G  G  G  G  GK+GAPG SG  G P   G +GP G+ G  G  G  G+PG  GPP
Sbjct: 990  GERGFPGLPGPSGEPGKQGAPGASGDRGPP---GPVGPPGLTGPAGEPGREGSPGADGPP 1046

Query: 1312 GKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHR 1371
            G+ G  G++G  G TG  GAPG PG  GS G  G  G QG +GE G  G  G  G  G R
Sbjct: 1047 GRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGAR 1106

Query: 1372 GAQGDQGPCGDPGLKGQPGEYGV---QGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHR 1428
            G QG QGP GD G  G+PGE G+   +G TG QG PGP GP GD G  G +GP GP G  
Sbjct: 1107 GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPP 1166

Query: 1429 GNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQMDINAAI 1488
            G  GP G++G  G  G  GP G +G  GETGP GP G PGPPGPPG PGP   M   A +
Sbjct: 1167 GPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGL 1226

Query: 1489 QALIESNTALQMESYQNTEVTLIDHSEEIFKTLNYLSNLLHSIKNPLGTRDNPARICKDL 1548
                +    LQ          L  H  E+  TL  L+N + SI++P G+R NPAR C+DL
Sbjct: 1227 GPREKGPDPLQYMRADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGSRKNPARTCRDL 1286

Query: 1549 LNCEQKVSDGKYWIDPNLGCPSDAIEVFCNFSAGGQTCL--PPVSVTK------------ 1594
              C  +   G YWIDPN GC  DA++VFCN    G+TC+   P +V K            
Sbjct: 1287 KLCHPEWKSGDYWIDPNQGCTLDAMKVFCNMET-GETCVYPNPANVPKKNWWSSKSKEKK 1345

Query: 1595 -LEFG-------------------VGKVQMNFLHLLSSEATHIITIHCLNTPRWTSTQTS 1634
             + FG                      VQM FL LLS+E +  IT HC N+  +      
Sbjct: 1346 HIWFGETINGGFHFSYGDDNLAPNTANVQMTFLRLLSTEGSQNITYHCKNSIAYLDEAAG 1405

Query: 1635 GPGLPIGFKGWNGQIFKV--NTLLEPKVLSDDCKIQDGSWHKATFLFHTQEPNQLPVIEV 1692
                 +  +G N    +   N+      L D C    G W K    + +Q+ ++LP+I++
Sbjct: 1406 NLKKALLIQGSNDVEIRAEGNSRFTYTALKDGCTKHTGKWGKTVIEYRSQKTSRLPIIDI 1465

Query: 1693 QKLPHLKTERKYYIDSSSVCFL 1714
              +     E+++ +D   VCFL
Sbjct: 1466 APMDIGGPEQEFGVDIGPVCFL 1487



 Score =  676 bits (1745), Expect = 0.0
 Identities = 397/919 (43%), Positives = 467/919 (50%), Gaps = 86/919 (9%)

Query: 485  EYLRGPKGDTGPPGPPGPA---------GIPGPSGKRGPRGI------PGPHGNPGLPGL 529
            E  +GP+G+ G PG PGPA         GIPG  G  G  GI      PGP G PG  G 
Sbjct: 386  EGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGA 445

Query: 530  PGPKGPK---GDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGI 586
             GP GPK   G+PG +  +   G KG+ G +G  G PG  G++G +G  G PG  G  G 
Sbjct: 446  TGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGP 505

Query: 587  PGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGF 646
            PG  G  G+ G+PG+ GLAGP+G PG +G  G  G  G  G  G  GE G+PG R     
Sbjct: 506  PGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR----- 560

Query: 647  KGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGN 706
             G  G PGD G +G  G  G+PG  G  GPPG  G RG  G +G  GP G  G  G +G 
Sbjct: 561  -GLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGE 619

Query: 707  KGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGP 766
            KGLPG  G +G  G  GE G  G PG  G  G  G  G  G SG  G  G PG  G  G 
Sbjct: 620  KGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGK 679

Query: 767  PGPEGFPGDIGIPGQNGPEGPKGLLGNRGPP------GPPGLKGTQGEEGPIGAFGELGP 820
            PG +G PG+ G PG  GP G +G  G RG P      GP GL GT G +GP GA G  GP
Sbjct: 680  PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGP 739

Query: 821  ---------RGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGE 871
                     +G PG++G AG  GP+G +G+VG++G  G  G+ G  GL G +G  G  G 
Sbjct: 740  PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 799

Query: 872  KGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGP 931
             GE+G  GP GP G  G  G PG  G  GP GP G  G  GA G PG++G +G+ G +G 
Sbjct: 800  NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGD 859

Query: 932  DGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGE 991
             G  G QG  GA G +G  G  GP G  G  G PG  GF G  G  G PGS G+ G PG 
Sbjct: 860  AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP 919

Query: 992  PGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGA 1051
            PG  G     GP G  G  GPPG  GE GLQG                 G PG +GEPG 
Sbjct: 920  PGPSGKD---GPKGARGDSGPPGRAGEPGLQGP---------------AGPPGEKGEPGD 961

Query: 1052 PGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQ 1111
             G  G +G  G +G+ G RG+ G  G++GE G PG+ GP G  G+ G PG  G  G PG 
Sbjct: 962  DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGP 1021

Query: 1112 RGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGY 1171
             G PG  G  G+ G  G  G+ GPPG+ G +G KG RG  GAVG  G  GP G PG  G 
Sbjct: 1022 VGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGP 1081

Query: 1172 RGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVG 1231
             G QG  G +G  GP G  G P     + GP GPRG      D+GE GEPG  G KGH  
Sbjct: 1082 TGKQGDRGEAGAQGPMGPSG-PAGARGIQGPQGPRG------DKGEAGEPGERGLKGH-- 1132

Query: 1232 VPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKG 1291
                RG TG QG PG PG  G+QG  G  G  G +G  G  GPSGK G  G+ G +GP G
Sbjct: 1133 ----RGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1188

Query: 1292 IQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQG 1351
             +G  G  G +G PG  GPPG  G PG                PG+  S+     P  +G
Sbjct: 1189 PRGRSGETGPAGPPGNPGPPGPPGPPG----------------PGIDMSAFAGLGPREKG 1232

Query: 1352 PKGEQGLPGQPGIQGKRGH 1370
            P   Q +       G R H
Sbjct: 1233 PDPLQYMRADQAAGGLRQH 1251


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score =  994 bits (2570), Expect = 0.0
 Identities = 577/1342 (42%), Positives = 692/1342 (51%), Gaps = 126/1342 (9%)

Query: 489  GPKGDTGPPGPPGPAGIPGPSGK---------------------RGPRGIPGPHGNPGLP 527
            G  G+ GPPGPPGP G PG  G                      +GP G  GP G PG  
Sbjct: 87   GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 146

Query: 528  GLPGPKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLP---GLPGEQ 584
            G PGP+G +G+PG  PG+  PG  G  G  G  GPPG  GD G  G PG     G PG Q
Sbjct: 147  GAPGPQGFQGNPG-EPGE--PGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 203

Query: 585  GIPGFAGNIGSPGYPGRQ---GLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIR 641
            G  GF G  G PG  G +   GL G +G  G  G +G  GSPGE G  GP G RG+PG R
Sbjct: 204  GARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGER 263

Query: 642  GKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGI---- 697
            G+ G  G  G  G+ G  GPAG  G  G  GG G PG PG +G  GP G  GP G     
Sbjct: 264  GRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPR 323

Query: 698  --------PGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKS 749
                    PGP G SGN G  GI G KG  G  G  G PG+PG +G    PGP G  G  
Sbjct: 324  GEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP---PGPQGATGPL 380

Query: 750  GPSGQTGDPGL------QGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLK 803
            GP GQTG+PG+      QGP G PGP G  G  G  G+ G  G +G  G  GP GPPG +
Sbjct: 381  GPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGER 440

Query: 804  GTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGE- 862
            G  G  G  G  G  GP+G PG++G +G  GP+G  G+ G  G  G  G  G  G PG+ 
Sbjct: 441  GAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDA 500

Query: 863  -----VGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGV---PGPIGPLGLPGHVGAR 914
                 VG +G+ GE G  G PGP G +G+ GVMG+PGP G    PG  G  GLPG  G R
Sbjct: 501  GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLR 560

Query: 915  GPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKP 974
            G PG  G  G  G  GP G  GE+G QGA G  G QG  GP G  G+ G PG++G  G+ 
Sbjct: 561  GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA 620

Query: 975  GLQGLPGSTGDRGLPGE---PGLRGLQGDVGPPGEMGME---------GPPGTEGESGLQ 1022
            G  GL G  G+RG PGE   PG +GLQG  G PG  G +         GPPG +G  GLQ
Sbjct: 621  GAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQ 680

Query: 1023 GEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGE---K 1079
            G PG +G  G AG  G  G+ G +G  GAPG++G +G  G  G PG  G  GE GE    
Sbjct: 681  GMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPP 740

Query: 1080 GEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKI 1139
            G  G  G  G  G  G+TG PGP G  G PG  G+PG KG++G+ G  G+ G+ GP G  
Sbjct: 741  GPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPS 800

Query: 1140 GKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTV 1199
            G  GP+G  G  G  G  G  GP G  G PG  G  G PG +G PGP G  G  G+D   
Sbjct: 801  GAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPK 860

Query: 1200 -----LGPPGPRGEP---GPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQ 1251
                  GPPG  GEP   GP G  GE+GEPG +G  G  G PG +G  GQ+G  G PG +
Sbjct: 861  GARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQR 920

Query: 1252 GEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPP 1311
            GE+G  G  G  G  GK+GAPG SG  G P   G +GP G+ G  G  G  G+PG  GPP
Sbjct: 921  GERGFPGLPGPSGEPGKQGAPGASGDRGPP---GPVGPPGLTGPAGEPGREGSPGADGPP 977

Query: 1312 GKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHR 1371
            G+ G  G++G  G TG  GAPG PG  GS G  G  G QG +GE G  G  G  G  G R
Sbjct: 978  GRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGAR 1037

Query: 1372 GAQGDQGPCGDPGLKGQPGEYGV---QGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHR 1428
            G QG QGP GD G  G+PGE G+   +G TG QG PGP GP GD G  G +GP GP G  
Sbjct: 1038 GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPP 1097

Query: 1429 GNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQMDINAAI 1488
            G  GP G++G  G  G  GP G +G  GETGP GP G PGPPGPPG PGP   M   A +
Sbjct: 1098 GPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGL 1157

Query: 1489 QALIESNTALQMESYQNTEVTLIDHSEEIFKTLNYLSNLLHSIKNPLGTRDNPARICKDL 1548
                +    LQ          L  H  E+  TL  L+N + SI++P G+R NPAR C+DL
Sbjct: 1158 GPREKGPDPLQYMRADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGSRKNPARTCRDL 1217

Query: 1549 LNCEQKVSDGKYWIDPNLGCPSDAIEVFCNFSAGGQTCL--PPVSVTK------------ 1594
              C  +   G YWIDPN GC  DA++VFCN    G+TC+   P +V K            
Sbjct: 1218 KLCHPEWKSGDYWIDPNQGCTLDAMKVFCNMET-GETCVYPNPANVPKKNWWSSKSKEKK 1276

Query: 1595 -LEFG-------------------VGKVQMNFLHLLSSEATHIITIHCLNTPRWTSTQTS 1634
             + FG                      VQM FL LLS+E +  IT HC N+  +      
Sbjct: 1277 HIWFGETINGGFHFSYGDDNLAPNTANVQMTFLRLLSTEGSQNITYHCKNSIAYLDEAAG 1336

Query: 1635 GPGLPIGFKGWNGQIFKV--NTLLEPKVLSDDCKIQDGSWHKATFLFHTQEPNQLPVIEV 1692
                 +  +G N    +   N+      L D C    G W K    + +Q+ ++LP+I++
Sbjct: 1337 NLKKALLIQGSNDVEIRAEGNSRFTYTALKDGCTKHTGKWGKTVIEYRSQKTSRLPIIDI 1396

Query: 1693 QKLPHLKTERKYYIDSSSVCFL 1714
              +     E+++ +D   VCFL
Sbjct: 1397 APMDIGGPEQEFGVDIGPVCFL 1418



 Score =  676 bits (1745), Expect = 0.0
 Identities = 397/919 (43%), Positives = 467/919 (50%), Gaps = 86/919 (9%)

Query: 485  EYLRGPKGDTGPPGPPGPA---------GIPGPSGKRGPRGI------PGPHGNPGLPGL 529
            E  +GP+G+ G PG PGPA         GIPG  G  G  GI      PGP G PG  G 
Sbjct: 317  EGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGA 376

Query: 530  PGPKGPK---GDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGI 586
             GP GPK   G+PG +  +   G KG+ G +G  G PG  G++G +G  G PG  G  G 
Sbjct: 377  TGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGP 436

Query: 587  PGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGF 646
            PG  G  G+ G+PG+ GLAGP+G PG +G  G  G  G  G  G  GE G+PG R     
Sbjct: 437  PGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR----- 491

Query: 647  KGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGN 706
             G  G PGD G +G  G  G+PG  G  GPPG  G RG  G +G  GP G  G  G +G 
Sbjct: 492  -GLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGE 550

Query: 707  KGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGP 766
            KGLPG  G +G  G  GE G  G PG  G  G  G  G  G SG  G  G PG  G  G 
Sbjct: 551  KGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGK 610

Query: 767  PGPEGFPGDIGIPGQNGPEGPKGLLGNRGPP------GPPGLKGTQGEEGPIGAFGELGP 820
            PG +G PG+ G PG  GP G +G  G RG P      GP GL GT G +GP GA G  GP
Sbjct: 611  PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGP 670

Query: 821  ---------RGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGE 871
                     +G PG++G AG  GP+G +G+VG++G  G  G+ G  GL G +G  G  G 
Sbjct: 671  PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 730

Query: 872  KGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGP 931
             GE+G  GP GP G  G  G PG  G  GP GP G  G  GA G PG++G +G+ G +G 
Sbjct: 731  NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGD 790

Query: 932  DGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGE 991
             G  G QG  GA G +G  G  GP G  G  G PG  GF G  G  G PGS G+ G PG 
Sbjct: 791  AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP 850

Query: 992  PGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGA 1051
            PG  G     GP G  G  GPPG  GE GLQG                 G PG +GEPG 
Sbjct: 851  PGPSGKD---GPKGARGDSGPPGRAGEPGLQGP---------------AGPPGEKGEPGD 892

Query: 1052 PGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQ 1111
             G  G +G  G +G+ G RG+ G  G++GE G PG+ GP G  G+ G PG  G  G PG 
Sbjct: 893  DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGP 952

Query: 1112 RGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGY 1171
             G PG  G  G+ G  G  G+ GPPG+ G +G KG RG  GAVG  G  GP G PG  G 
Sbjct: 953  VGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGP 1012

Query: 1172 RGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVG 1231
             G QG  G +G  GP G  G P     + GP GPRG      D+GE GEPG  G KGH  
Sbjct: 1013 TGKQGDRGEAGAQGPMGPSG-PAGARGIQGPQGPRG------DKGEAGEPGERGLKGH-- 1063

Query: 1232 VPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKG 1291
                RG TG QG PG PG  G+QG  G  G  G +G  G  GPSGK G  G+ G +GP G
Sbjct: 1064 ----RGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1119

Query: 1292 IQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQG 1351
             +G  G  G +G PG  GPPG  G PG                PG+  S+     P  +G
Sbjct: 1120 PRGRSGETGPAGPPGNPGPPGPPGPPG----------------PGIDMSAFAGLGPREKG 1163

Query: 1352 PKGEQGLPGQPGIQGKRGH 1370
            P   Q +       G R H
Sbjct: 1164 PDPLQYMRADQAAGGLRQH 1182



 Score =  540 bits (1391), Expect = e-153
 Identities = 334/780 (42%), Positives = 386/780 (49%), Gaps = 135/780 (17%)

Query: 832  EPGPEGLKGEVGD-QGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVM 890
            +PGP+G KGE GD +  +G  G  GP G  GE G  G  G+KGE+G+PGP G  GE G  
Sbjct: 30   QPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTP 89

Query: 891  GYPGPPGVPGPIGPLGLPGHVGAR---------------------GPPGSQGPKGQRGSR 929
            G PGPPG PGP GP GL G+  A+                     GP G +GP G  G+ 
Sbjct: 90   GNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAP 149

Query: 930  GPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLP 989
            GP G  G  G  G  G  G  G RGP G  GK G+ GE G  GK G +G PG  G RG P
Sbjct: 150  GPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFP 209

Query: 990  GEPGLRGLQGDVGPP---GEMGMEGPPGTEGESGLQGE------------PGAKGDVGTA 1034
            G PGL G++G  G P   G  G  G PG +GESG  GE            PG +G  G A
Sbjct: 210  GTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPA 269

Query: 1035 GS------------------VGGTGEPGLRGEPGAPGE---------EGLQGKDGLKGVP 1067
            G+                  VG  G PG  G PGA GE         EG QG  G  G P
Sbjct: 270  GAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTP 329

Query: 1068 ------GGRGLPGED---GEKGEMGLPGIIGPLGRSGQTGLPGPEGI---VGIPGQRGRP 1115
                  G  G PG D   G KG  G PGI G  G  G  G PGP+G    +G  GQ G P
Sbjct: 330  GSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEP 389

Query: 1116 GKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQ 1175
            G  G KG+ GP GE G  GP G  G +G +G RG RG  G +G +GP GE G PG RG  
Sbjct: 390  GIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFP 449

Query: 1176 GQP------------GPSGLPGPKGEKGYPGEDST-----------------------VL 1200
            GQ             GPSGL GPKG  G PG                             
Sbjct: 450  GQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPS 509

Query: 1201 GPPGPRGEPGPVGDQGERGEP---------GAEGYKGHVGVPGLRGATGQQGPPGEPGDQ 1251
            G PG  G PGP G QG RG+P         GA G  G  G  GL GA G +G PG+ G+ 
Sbjct: 510  GAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGET 569

Query: 1252 GEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPP 1311
            G  G  G  G  G +G++GAPGPSG  G+PG  G  G  G  G  G  G +G PG +GP 
Sbjct: 570  GAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPR 629

Query: 1312 GKQGLPGIRGGPGR------TGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQ 1365
            G++G PG RG PG        GL G PG  G KG+SG  G PG QGP G QG+PG+   +
Sbjct: 630  GERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGE---R 686

Query: 1366 GKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGP---- 1421
            G  G  G +GD+G  G+ G +G PG+ G +GLTG  G PGP G  G+ G VG  GP    
Sbjct: 687  GAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSA 746

Query: 1422 --KGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPR 1479
              +G  G RG TGP G  G  GP G  G  G KG +GE G +G  G PGP GP GAPGP+
Sbjct: 747  GARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQ 806


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  955 bits (2469), Expect = 0.0
 Identities = 575/1342 (42%), Positives = 682/1342 (50%), Gaps = 127/1342 (9%)

Query: 470  YDYYYYEDLNTMLEMEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGL 529
            YD Y   D+ + + +  L G  G  GPPGPPGP   PG SG  G  G PG  G PG PG 
Sbjct: 155  YDSY---DVKSGVAVGGLAGYPGPAGPPGPPGP---PGTSGHPGSPGSPGYQGPPGEPGQ 208

Query: 530  PGPKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGF 589
             GP GP G PG        G  G  G  G  G PG  G++GL   PG PG+ G  GIPGF
Sbjct: 209  AGPSGPPGPPG------AIGPSGPAGKDGESGRPGRPGERGL---PGPPGIKGPAGIPGF 259

Query: 590  AGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGR 649
             G  G  G+ GR G  G  G PG KG  G    PGE G  GP G RG PG RG+ G  G 
Sbjct: 260  PGMKGHRGFDGRNGEKGETGAPGLKGENGL---PGENGAPGPMGPRGAPGERGRPGLPGA 316

Query: 650  QGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGP--------- 700
             G  G+ G RG  G  G PG  G  G PG PG +G VGP G  G  G PG          
Sbjct: 317  AGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGH 376

Query: 701  MGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGL 760
             G  G  G PGI G  G +G  G  G PG PG  GA G PGP G  G  G  G  G+PG 
Sbjct: 377  AGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGK 436

Query: 761  QGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGP 820
             G  G PGP G  G+ GIPG  G +G  G  G+ G PG  GL G  GE G  G  G  GP
Sbjct: 437  NGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGP 496

Query: 821  RGKPGQKGYAGE---PGPEGLKGEVGDQGNIGKIGETGPVGLP---------GEVGMTGS 868
             G PG+KG AGE   PGP G +G  G+ G  G  G  G  G+P         G+ G  GS
Sbjct: 497  NGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGS 556

Query: 869  IGEKGERGSPGPLGPQGEKGVMGYPGP---PGVPGPIGPLGLPGHVGARGPPGSQGPKGQ 925
             GE G  G PGP GP+G+ GVMG+PGP    G PG  G  G PG  G +GPPG  G  G 
Sbjct: 557  QGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGP 616

Query: 926  RGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGD 985
            +G  GP G  G++G  G  G +G QG  G  G  G+ G PGE G +G  G  G PG  GD
Sbjct: 617  QGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGD 676

Query: 986  RGLPGE---PGLR---GLQGDVGPP------GEMGMEGPPGTEGESGLQGEPGAKGDVGT 1033
             G PGE   PGL    GL+G  GPP      G  G  GPPG  G  GLQG PG +G +G+
Sbjct: 677  AGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGS 736

Query: 1034 AGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPL-- 1091
             G  G  GEPG  G  G PG++G +G  G  G PG  G PG+ GE G  GLPGI GP   
Sbjct: 737  PGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGS 796

Query: 1092 -GRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGT 1150
             G  G+TG PGP G  G PGQ G PG KG++G  G  GE G  G  G  G SGP G  G 
Sbjct: 797  PGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGP 856

Query: 1151 RGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPG 1210
            +G  G  G  G  G  G PG RG  G PG +G PGP G  G PG+D          G PG
Sbjct: 857  QGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKD----------GPPG 906

Query: 1211 PVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGER---GSEGNKG 1267
            P G+ G  G PG  G KG  G PG +G+ G QGPPG PG  G  G+ G R   G  G  G
Sbjct: 907  PAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPG 966

Query: 1268 KKGAPGP------SGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRG 1321
             +G+PGP      SGKPG  GL G  GP G QG  G  G +G PG+ G PG  GLPG  G
Sbjct: 967  PRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDG 1026

Query: 1322 GPGRTGLAGAPGPPGVKGSSGLPGSPGIQGP------KGEQGLPGQPGIQGKRGHRGAQG 1375
             PG  G  G  G PG  G+ G PG PG  GP      +GE G  G  G  G  G RGA G
Sbjct: 1027 SPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPG 1086

Query: 1376 DQGPCGDPGLKGQPGEYGVQGLTGF---QGFPGPKGPEGDAGIVGISGPKGPIGHRGNTG 1432
             QGP GD G  G+ G  G++G  GF    G PG  GP G  G +G  GP GP G  G +G
Sbjct: 1087 PQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSG 1146

Query: 1433 PLGREGII---GPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQMDINAAIQ 1489
            P G++G     GP G  GPRG +G RG  G  G  GQPGPPGPPGAPGP     + AA  
Sbjct: 1147 PPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCG-GVGAAAI 1205

Query: 1490 ALIESNTALQMESYQNTE-VTLIDHSEEIFKTLNYLSNLLHSIKNPLGTRDNPARICKDL 1548
            A I    A     Y   E +    +++EI  +L  ++  + S+ +P G+R NPAR C+DL
Sbjct: 1206 AGIGGEKAGGFAPYYGDEPMDFKINTDEIMTSLKSVNGQIESLISPDGSRKNPARNCRDL 1265

Query: 1549 LNCEQKVSDGKYWIDPNLGCPSDAIEVFCNFSAGGQTCLP--PVSVTK------------ 1594
              C  ++  G+YW+DPN GC  DAI+VFCN    G+TC+   P++V +            
Sbjct: 1266 KFCHPELKSGEYWVDPNQGCKLDAIKVFCNMET-GETCISANPLNVPRKHWWTDSSAEKK 1324

Query: 1595 -----------LEFGVGK---------VQMNFLHLLSSEATHIITIHCLNTPRWTSTQTS 1634
                        +F  G          VQ+ FL LLSS A+  IT HC N+  +    + 
Sbjct: 1325 HVWFGESMDGGFQFSYGNPELPEDVLDVQLAFLRLLSSRASQNITYHCKNSIAYMDQASG 1384

Query: 1635 GPGLPIGFKGWNGQIFKV--NTLLEPKVLSDDCKIQDGSWHKATFLFHTQEPNQLPVIEV 1692
                 +   G N   FK   N+     VL D C    G W K  F + T++  +LP++++
Sbjct: 1385 NVKKALKLMGSNEGEFKAEGNSKFTYTVLEDGCTKHTGEWSKTVFEYRTRKAVRLPIVDI 1444

Query: 1693 QKLPHLKTERKYYIDSSSVCFL 1714
                    ++++ +D   VCFL
Sbjct: 1445 APYDIGGPDQEFGVDVGPVCFL 1466



 Score =  625 bits (1611), Expect = e-178
 Identities = 371/843 (44%), Positives = 428/843 (50%), Gaps = 87/843 (10%)

Query: 688  PVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPG-----P 742
            P  P  P    GP G  G+ G PGI G  G+ G       PG PG  G+ G PG     P
Sbjct: 92   PTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGI------PGQPGSPGSPGPPGICESCP 145

Query: 743  PGMRG----------KSGPS--GQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGL 790
             G +           KSG +  G  G PG  GP GPPGP G  G  G PG  G +GP G 
Sbjct: 146  TGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGE 205

Query: 791  LGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGK 850
             G  GP GPPG  G  G  GP G  GE G  G+PG++G    PGP G+KG  G  G  G 
Sbjct: 206  PGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGL---PGPPGIKGPAGIPGFPGM 262

Query: 851  IGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGH 910
             G  G  G  GE G TG+ G KGE G P      GE G  G  GP G PG  G  GLPG 
Sbjct: 263  KGHRGFDGRNGEKGETGAPGLKGENGLP------GENGAPGPMGPRGAPGERGRPGLPGA 316

Query: 911  VGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGF 970
             GARG  G++G  GQ G  GP G  G  G  GAKGE G  G  G +G  G+ G PG +G 
Sbjct: 317  AGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGH 376

Query: 971  ------QGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTE------GE 1018
                   G PG+ G PG  G+ G  G PG  GL G  GPPG  G  G PG        G+
Sbjct: 377  AGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGK 436

Query: 1019 SGLQGEPGAKGDVGTA---GSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGR----- 1070
            +G +GEPG +G+ G A   G  G  GE G  G PG PG  GL G  G +G PG R     
Sbjct: 437  NGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGP 496

Query: 1071 -GLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGE 1129
             G+PGE G  GE G PG  GP G +G+   PG +G+ G PG RG PG  G  G  G  G 
Sbjct: 497  NGIPGEKGPAGERGAPGPAGPRGAAGE---PGRDGVPGGPGMRGMPGSPGGPGSDGKPGP 553

Query: 1130 VGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGE 1189
             GS+G  G+ G  GP G RG  G +G  G  G DG PG  G RG  G PGP G PG  GE
Sbjct: 554  PGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGE 613

Query: 1190 KGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPG 1249
                       GP GP G  GP GD+G+ G PG +G +   G+PG  G  G+ G PGEPG
Sbjct: 614  ----------TGPQGPPGPTGPGGDKGDTGPPGPQGLQ---GLPGTGGPPGENGKPGEPG 660

Query: 1250 DQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIG 1309
             +G+ G  G  G +G+ G  G  GP G  G PGL+G  GP G +G  GA G  G PG  G
Sbjct: 661  PKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAG 720

Query: 1310 PPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGP---------------KG 1354
             PG QG+PG RGG G  G  G  G PG  G+ G+PG  G +GP               KG
Sbjct: 721  TPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKG 780

Query: 1355 EQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAG 1414
            E G PG PGI G RG  G +G+ GP G  G  G PG+ G  G  G +G PG K   G+ G
Sbjct: 781  EGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEK---GEGG 837

Query: 1415 IVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPG 1474
              G++GP G  G  G  GP G +G  G  G  G  G  G RG  GP G  G PGPPGP G
Sbjct: 838  PPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSG 897

Query: 1475 APG 1477
            +PG
Sbjct: 898  SPG 900



 Score =  541 bits (1394), Expect = e-153
 Identities = 332/800 (41%), Positives = 388/800 (48%), Gaps = 121/800 (15%)

Query: 761  QGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGP 820
            Q P+ P  P         P   GP+GPKG       PGPPG+ G  G+ G          
Sbjct: 90   QPPTAPTRP---------PNGQGPQGPKG------DPGPPGIPGRNGDPG---------- 124

Query: 821  RGKPGQKGYAGEPGPEGLKGEVG----------------DQGNI-------GKIGETGPV 857
                      G+PG  G  G  G                D  ++       G  G  GP 
Sbjct: 125  --------IPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPA 176

Query: 858  GLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPP 917
            G PG  G  G+ G  G  GSPG  GP GE G  G  GPPG PG IGP G  G  G  G P
Sbjct: 177  GPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRP 236

Query: 918  GSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQ 977
            G     G+RG  GP G+ G  GI G  G KG +G  G +G  G+TG PG +G  G PG  
Sbjct: 237  GR---PGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGEN 293

Query: 978  GLPGSTGDRGLPGE------PGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDV 1031
            G PG  G RG PGE      PG  G +G+ G  G  G  GPPG  G +G  G PGAKG+V
Sbjct: 294  GAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEV 353

Query: 1032 GTAGSVGGTGEPGLRGEPGAPGEEGLQ---GKDGLKGVPGGRGLPGEDGEKGEMGLPGII 1088
            G AGS G  G PG RGEPG  G  G Q   G  G+ G PGG+G  G  G  G  GL G  
Sbjct: 354  GPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGAR 413

Query: 1089 GPLGRSGQTGLPGPEGIVGIPGQ---RGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPK 1145
            GP G +G  G PG  G  G PG+   +G PG +G++G+ G  G  G++G  GK G  G  
Sbjct: 414  GPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEP 473

Query: 1146 GARGTRGAVGHL---GLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGP 1202
            GA G  GA G     G  GP G  GIPG +G  G+ G  G  GP+G  G PG D    GP
Sbjct: 474  GANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGP 533

Query: 1203 -----------PGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLR--------------- 1236
                       PG  G+PGP G QGE G PG  G  G  G PG+                
Sbjct: 534  GMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKN 593

Query: 1237 ------GATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGL------Q 1284
                  G  G QGPPG+ G+ G QG  G  G  G+KG  G PGP G  G+PG        
Sbjct: 594  GERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGEN 653

Query: 1285 GLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLP 1344
            G  G  G +G  GA G  G  G  G PG++G PG+ G PG  G AG PGP G KG++G P
Sbjct: 654  GKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPP 713

Query: 1345 GSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFP 1404
            G PG  G  G QG+PG+   +G  G  G +GD+G  G PG  G PG+ G +G TG  G P
Sbjct: 714  GPPGAAGTPGLQGMPGE---RGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPP 770

Query: 1405 GPKGPEGD------AGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGET 1458
            GP G  GD       G+ GI+GP+G  G RG TGP G  G  G  G+ G  G KG RG  
Sbjct: 771  GPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAP 830

Query: 1459 GPQGPRGQPGPPGPPGAPGP 1478
            G +G  G PG  GPPG  GP
Sbjct: 831  GEKGEGGPPGVAGPPGGSGP 850



 Score =  440 bits (1131), Expect = e-123
 Identities = 272/666 (40%), Positives = 323/666 (48%), Gaps = 75/666 (11%)

Query: 861  GEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQ 920
            G V     I +  E   P P  P GE   +  P PP  P                PP  Q
Sbjct: 58   GSVLCDDIICDDQELDCPNPEIPFGECCAV-CPQPPTAP--------------TRPPNGQ 102

Query: 921  GPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTG------------NPGER 968
            GP+G +G  GP G      I G  G+ G  G+ G  G  G  G            +P   
Sbjct: 103  GPQGPKGDPGPPG------IPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYD 156

Query: 969  GFQGKP-----GLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQG 1023
             +  K      GL G PG  G  G PG PG  G  G  G PG  G  G PG  G SG  G
Sbjct: 157  SYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPG 216

Query: 1024 EPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVP---GGRGLPGEDGEKG 1080
             PGA G  G AG  G +G PG  GE G PG  G++G  G+ G P   G RG  G +GEKG
Sbjct: 217  PPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKG 276

Query: 1081 EMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRP------------GKKGDKGQIGPTG 1128
            E G PG+ G  G  G+ G PGP G  G PG+RGRP            G +G  GQ GP G
Sbjct: 277  ETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPG 336

Query: 1129 EVGSR------------GPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQG 1176
              G+             GP G  G +G  G RG  G  GH G  GP G PGI G  G +G
Sbjct: 337  PPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKG 396

Query: 1177 QPGPSGLPGP---KGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVP 1233
            + GP+G+PG     G +G PG  +   G PG RG  G  G  G +GEPG  G +G  G+P
Sbjct: 397  EMGPAGIPGAPGLMGARGPPG-PAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIP 455

Query: 1234 GLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQ 1293
            G+ GA G+ G  G PG+ G  GL    G+ G +G  G  GP+G  GIPG +G  G +G  
Sbjct: 456  GVPGAKGEDGKDGSPGEPGANGLP---GAAGERGAPGFRGPAGPNGIPGEKGPAGERGAP 512

Query: 1294 GYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPK 1353
            G  G  G +G PG+ G PG  G+ G+ G PG  G  G PGPPG +G SG PG PG  GP+
Sbjct: 513  GPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPR 572

Query: 1354 GEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDA 1413
            G+ G+ G PG +G  G  G  G++G  G PG +G PG+    G TG QG PGP GP GD 
Sbjct: 573  GQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGK---NGETGPQGPPGPTGPGGDK 629

Query: 1414 GIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPP 1473
            G  G  GP+G  G  G  GP G  G  G  G  G  G  G  G  G  G  G+ GPPG  
Sbjct: 630  GDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLA 689

Query: 1474 GAPGPR 1479
            GAPG R
Sbjct: 690  GAPGLR 695


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  946 bits (2445), Expect = 0.0
 Identities = 559/1312 (42%), Positives = 677/1312 (51%), Gaps = 122/1312 (9%)

Query: 489  GPKGDTGPPGPPGPAGI------PGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFS 542
            GP G TG PGP GP G       PG  G +GPRG+ GP G  G PG  G  G  G  G  
Sbjct: 562  GPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGM- 620

Query: 543  PGQPVP-GEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGR 601
            PGQ  P G++G  GL+GL G  G +GD G  G PG PG  GE+G  G  G  G PG PG 
Sbjct: 621  PGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGP 680

Query: 602  QGLAGPEGNPGPKGAQGFIG---SPGEAGQLGPEGERGIPGIRGK---KGFKGRQGFPGD 655
            +GL GP+G PGP G  G  G    PG  G +GP+GE G PG +G    +G  G QG  G 
Sbjct: 681  RGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGP 740

Query: 656  FGDRGPAGLDGSPGLVGGTGPPGFPGL------RGSVGPVGPIGPAGIPGPMGLSGN--- 706
             G++GP G  G PG+ G  GPPG PG       +G  GP GP GP G PGP G+ G    
Sbjct: 741  PGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGI 800

Query: 707  KGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGP 766
            +GL G KG+KGE G  G  G+ G  GD+G +G PGP G  G  GP G+ G  G  GP GP
Sbjct: 801  RGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGP 860

Query: 767  PGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKG---TQGEEGPIGAFGELGPRGK 823
            PG +G  G  G+PG  G +GPKG +G  G PG  G KG   T G+ GP G  G  GPRG+
Sbjct: 861  PGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGE 920

Query: 824  PGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGP 883
             G +G  G+PGP+G  G  G  G  G+ G  GP G  G  G  G  G  G+ G PG  G 
Sbjct: 921  RGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQ 980

Query: 884  QGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGA 943
            +GE G  G  GPPG PG +GP         +GP G  GP G+RG  GP G  GEQG+ G 
Sbjct: 981  RGETGFQGKTGPPGPPGVVGP---------QGPTGETGPMGERGHPGPPGPPGEQGLPGL 1031

Query: 944  KGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGP 1003
             G++G +G  GP GL GK G PG RGF G            DRGLPG  G  GL+G+ GP
Sbjct: 1032 AGKEGTKGDPGPAGLPGKDGPPGLRGFPG------------DRGLPGPVGALGLKGNEGP 1079

Query: 1004 PGEMGMEGPPGTEGESGLQGE---PGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGK 1060
            PG  G  G PG  G +G  G    PG  G  G  G  G  G PG +G  G  G +GLQG 
Sbjct: 1080 PGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGP 1139

Query: 1061 DGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGD 1120
             GL G  G  G PGEDG+KGE+G PG  G  G  G+ G PGP    G  G  G+PG  G 
Sbjct: 1140 VGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGP---TGPQGPIGQPGPSGA 1196

Query: 1121 KGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGP 1180
             G+ GP      RG  G  G+ G +G RG  G  G +GL G  G PG  G  G  GQ GP
Sbjct: 1197 DGEPGP------RGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGP 1250

Query: 1181 SGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVP---GLRG 1237
             G PGP+G  G PG D    GPPG  G PG VG++GE GE G  G  G  G P   G RG
Sbjct: 1251 PGPPGPRGPSGAPGADGP-QGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERG 1309

Query: 1238 ATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHG 1297
              G+ GP G  G  G +G  G+ G +G+ G  G PG  G PG PG  G  GP G +G  G
Sbjct: 1310 EKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDG 1369

Query: 1298 ADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQG 1357
              G +G+PG  G PG  G PG RG PG  G  G  G  G KG +GL G PG  GP G QG
Sbjct: 1370 EPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQG 1429

Query: 1358 LPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVG 1417
             PG+PG  G RG  G  G+QG  G PG  G PG  G  GL G +G  GPKG +G  G++G
Sbjct: 1430 APGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIG 1489

Query: 1418 ISGP------------------KGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETG 1459
            + GP                   GP G +G TGP G  G  GP G  GP G KG +G +G
Sbjct: 1490 LIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSG 1549

Query: 1460 PQGPRGQPGPPGPPGAPGPRKQMDINAAIQALIESNTALQMESYQ-------NTEVTLID 1512
            P GP+G+ G PGPPG PGP  ++     IQA   S T   +++ Q          V   D
Sbjct: 1550 PTGPKGEAGHPGPPGPPGPPGEVIQPLPIQA---SRTRRNIDASQLLDDGNGENYVDYAD 1606

Query: 1513 HSEEIFKTLNYLSNLLHSIKNPLGTRDNPARICKDLLNCEQKVSDGKYWIDPNLGCPSDA 1572
              EEIF +LN L   +  +K PLGT+ NPAR CKDL  C     DG+YW+DPN GC  D+
Sbjct: 1607 GMEEIFGSLNSLKLEIEQMKRPLGTQQNPARTCKDLQLCHPDFPDGEYWVDPNQGCSRDS 1666

Query: 1573 IEVFCNFSAGGQTCLPPVSVTK----------------LEF--------------GVGKV 1602
             +V+CNF+AGG TC+ P   ++                 EF               VG V
Sbjct: 1667 FKVYCNFTAGGSTCVFPDKKSEGARITSWPKENPGSWFSEFKRGKLLSYVDAEGNPVGVV 1726

Query: 1603 QMNFLHLLSSEATHIITIHCLNTPRWTSTQTSGPGLPIGFKGWNGQIFKVNTLLEPKVLS 1662
            QM FL LLS+ A   +T HC  +  W    T      + F G N +    +     + L 
Sbjct: 1727 QMTFLRLLSASAHQNVTYHCYQSVAWQDAATGSYDKALRFLGSNDEEMSYDNNPYIRALV 1786

Query: 1663 DDCKIQDGSWHKATFLFHTQEPNQLPVIEVQKLPHLKTERKYYIDSSSVCFL 1714
            D C  + G + K      T +  Q+P++++      +  +K+  +    CF+
Sbjct: 1787 DGCATKKG-YQKTVLEIDTPKVEQVPIVDIMFNDFGEASQKFGFEVGPACFM 1837



 Score = 65.1 bits (157), Expect = 6e-10
 Identities = 46/178 (25%), Positives = 84/178 (47%), Gaps = 9/178 (5%)

Query: 87  DAYIETPFVKILPVN-LGQPFTILTGLQSHRVNNAFLFSIRNKNRLQ-LGVQL--LPKKL 142
           DA +  P  ++ P +   + F+ILT +++ + + AFL SI N+  +Q +G++L   P  L
Sbjct: 80  DAQLSAPTKQLYPASAFPEDFSILTTVKAKKGSQAFLVSIYNEQGIQQIGLELGRSPVFL 139

Query: 143 VVHIRGKQ-----PAVFNYSVHDEQWHSFAITIRNQSVSMFVECGKKYFSTETIPEVQTF 197
                GK      P     ++ D +WH  A+++  ++V++ ++C KK        +    
Sbjct: 140 YEDHTGKPGPEDYPLFRGINLSDGKWHRIALSVHKKNVTLILDCKKKTTKFLDRSDHPMI 199

Query: 198 DSNSVFTLGSMNNNSIHFEGIVCQLDIIPSAEASADYCRYVKQQCRQADKYQPETSIP 255
           D N +   G+   +   FEG + QL  +    A+ DYC +    C  A    P++  P
Sbjct: 200 DINGIIVFGTRILDEEVFEGDIQQLLFVSDHRAAYDYCEHYSPDCDTAVPDTPQSQDP 257


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  945 bits (2442), Expect = 0.0
 Identities = 572/1370 (41%), Positives = 686/1370 (50%), Gaps = 157/1370 (11%)

Query: 487  LRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLP---------------- 530
            + GPKGDTGP GP GPAG PG  G  G  G+PGP G PG PG P                
Sbjct: 110  VEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDE 169

Query: 531  ------------GPKGPKGDPGFSPGQP-------VPGEKGDQGLSGLM------GPPGM 565
                        GP GP+G PG  PG P        PGE G+ G SG M      GPPG 
Sbjct: 170  KSTGGISVPGPMGPSGPRGLPG-PPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGK 228

Query: 566  QGDKGLKGHPGLP---GLPGEQ---GIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGF 619
             GD G  G PG P   G PG Q   G+PG AG  G  G+ G  GL G +G+ GP G +G 
Sbjct: 229  NGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGE 288

Query: 620  IGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGF 679
             GSPGE G  G  G RG+PG RG+ G  G  G  G+ G  G A   G PG  G  GPPGF
Sbjct: 289  PGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAA---GPPGPTGPAGPPGF 345

Query: 680  PGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGL 739
            PG  G+ G  GP GP G  GP G+ G  G PG  G  G  G  G  G+PG  G  GA G+
Sbjct: 346  PGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGI 405

Query: 740  ---PGPPGMRGKSGPSGQTGDPGLQGPSGPP---------GPEGFPGDIGIPGQNGPEGP 787
               PG PG RG SGP G  G PG +G SG P         G +G PG +G+ G  GP G 
Sbjct: 406  AGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGE 465

Query: 788  KGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGE---PGPEGLKGEVGD 844
            +G  G RG PGP GL G  GE G  G+ G  G  G  G KG AGE   PGP G KG  G+
Sbjct: 466  EGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGE 525

Query: 845  QGNIGKI------GETGPVGLPGEVGMTGSIGEKGERGSPGPLGP---QGEKGVMGYPGP 895
             G  G+       G TG  G PG  G TG  G  G+ G PGP GP   +G+ GVMG+PGP
Sbjct: 526  AGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGP 585

Query: 896  ---------------PGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGI 940
                           PG PG +GP G  G  GA+GPPG  GP G+RG +GP G  G QG+
Sbjct: 586  KGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGL 645

Query: 941  QGAKGEKGDQGKRGPHGLIGKTGNP------GERGFQGKPGLQGLPGSTGDRGLPGEPGL 994
             G  G  G+ GK G  G+ G  G P      GERGF G+ G+QG PG  G RG  G PG 
Sbjct: 646  PGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGN 705

Query: 995  RGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGE 1054
             G +GD G P      G PG++G  GLQG PG +G  G  G  G  G+ G +G  G+PG+
Sbjct: 706  DGAKGDAGAP------GAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGK 759

Query: 1055 EGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGI------ 1108
            +G++G  G  G PG  G PG+ GE G  G  G  G  G  G  G PGP G  G       
Sbjct: 760  DGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGA 819

Query: 1109 ---PGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGK---SGPKGARGTRGAVGHLGLMGP 1162
               PG +G PG  G KG  GP G  G  GPPG IG     G KGARG+ G  G  G  G 
Sbjct: 820  DGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGA 879

Query: 1163 DGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPG 1222
             G  G PG  G+ G PGP G  G +G KG  GE     G PG  G PGP G  GE+G PG
Sbjct: 880  AGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPA-GRPGEVGPPGPPGPAGEKGSPG 938

Query: 1223 AEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPG 1282
            A+G  G  G PG +G  GQ+G  G PG +GE+G  G  G  G  GK+G  G SG+ G P 
Sbjct: 939  ADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPP- 997

Query: 1283 LQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSG 1342
              G +GP G+ G  G  G  G PG  G PG+ G PG +G  G TG AG PG PG  G+ G
Sbjct: 998  --GPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPG 1055

Query: 1343 LPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQG 1402
              G  G  G +GE G  G  G  G  G RG  G QGP GD G  G+ G+ G++G  GF G
Sbjct: 1056 PVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSG 1115

Query: 1403 FPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQG 1462
              GP GP G  G  G SG  GP G RG  G  G  G  G  G  GP G  G RG TG  G
Sbjct: 1116 LQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAG 1175

Query: 1463 PRGQPGPPGPPGAPGPRKQMDINAAIQALIESNTALQMESYQNTEVTLI-DHSEEIFKTL 1521
            P G PGPPGPPG PGP       + +    +         Y+  +  ++ D   E+  TL
Sbjct: 1176 PVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRYYRADDANVVRDRDLEVDTTL 1235

Query: 1522 NYLSNLLHSIKNPLGTRDNPARICKDLLNCEQKVSDGKYWIDPNLGCPSDAIEVFCNFSA 1581
              LS  + +I++P G+R NPAR C+DL  C      G+YWIDPN GC  DAI+VFCN   
Sbjct: 1236 KSLSQQIENIRSPEGSRKNPARTCRDLKMCHSDWKSGEYWIDPNQGCNLDAIKVFCNMET 1295

Query: 1582 GGQTCLPPV--SVTKLEFGVGK---------------------------------VQMNF 1606
             G+TC+ P   SV +  + + K                                 +Q+ F
Sbjct: 1296 -GETCVYPTQPSVAQKNWYISKNPKDKRHVWFGESMTDGFQFEYGGQGSDPADVAIQLTF 1354

Query: 1607 LHLLSSEATHIITIHCLNTPRWTSTQTSGPGLPIGFKGWNGQIFKV--NTLLEPKVLSDD 1664
            L L+S+EA+  IT HC N+  +   QT      +  +G N    +   N+     V  D 
Sbjct: 1355 LRLMSTEASQNITYHCKNSVAYMDQQTGNLKKALLLQGSNEIEIRAEGNSRFTYSVTVDG 1414

Query: 1665 CKIQDGSWHKATFLFHTQEPNQLPVIEVQKLPHLKTERKYYIDSSSVCFL 1714
            C    G+W K    + T + ++LP+I+V  L     ++++  D   VCFL
Sbjct: 1415 CTSHTGAWGKTVIEYKTTKTSRLPIIDVAPLDVGAPDQEFGFDVGPVCFL 1464



 Score =  506 bits (1302), Expect = e-142
 Identities = 306/752 (40%), Positives = 357/752 (47%), Gaps = 134/752 (17%)

Query: 860  PGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARG---- 915
            P +   TG  G KG+ G  GP GP G  G  G PG PG+PGP GP G PG  G  G    
Sbjct: 102  PTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAP 161

Query: 916  ---------------PPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGD------QGKRG 954
                            PG  GP G RG  GP G  G QG QG  GE G+       G RG
Sbjct: 162  QLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRG 221

Query: 955  PHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGL------------QGDVG 1002
            P G  GK G+ GE G  G+PG +G PG  G RGLPG  GL G+            +GD G
Sbjct: 222  PPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAG 281

Query: 1003 P---------------PGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRG 1047
            P               PG+MG  G PG  G  G  G  GA+G+ G  G+ G  G  G  G
Sbjct: 282  PAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAG 341

Query: 1048 EPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVG 1107
             PG PG  G +G+ G +G  G  G  G  GE G  G  G  GP G  G  G PG +G  G
Sbjct: 342  PPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANG 401

Query: 1108 IPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGH---LGLMGPDG 1164
             PG  G PG  G +G  GP G  G  GP G  G+ G  G++G  GA G    +G+ GP G
Sbjct: 402  APGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPG 461

Query: 1165 EPGIPGYRGHQGQPGPSGLPGPKGE------KGYPGEDSTVLGPPGPRGEPGPVGDQGER 1218
              G  G RG +G+PGP+GLPGP GE      +G+PG D  V GP GP GE G  G  G +
Sbjct: 462  PAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADG-VAGPKGPAGERGSPGPAGPK 520

Query: 1219 GEPGAEGYKGHVGVPGLRGAT---------------------GQQGPPGEPGDQGEQGL- 1256
            G PG  G  G  G+PG +G T                     G+ GPPG PG +G+ G+ 
Sbjct: 521  GSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVM 580

Query: 1257 -----KGERGSEGNKGKKGAPGP------------------------------SGKPGIP 1281
                 KG  G  G  G++G PGP                               G  G P
Sbjct: 581  GFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSP 640

Query: 1282 GLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSS 1341
            G QGL GP G  G  G  G  G PG +G PG  G  G RG PG  G+ G PGP G +G++
Sbjct: 641  GFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGAN 700

Query: 1342 GLPGSPGIQGPKGEQGLPGQ---PGIQGKRGHRGA------QGDQGPCGDPGLKGQPGEY 1392
            G PG+ G +G  G  G PG    PG+QG  G RGA      +GD+G  G  G  G PG+ 
Sbjct: 701  GAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKD 760

Query: 1393 GVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPI------GHRGNTGPLGREGIIGPTGRT 1446
            GV+GLTG  G PGP G  GD G  G SGP GP       G RG  GP G  G  GP G  
Sbjct: 761  GVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGAD 820

Query: 1447 GPRGEKGFRGETGPQGPRGQPGPPGPPGAPGP 1478
            G  G KG  G+ G +G  G PGP GP G PGP
Sbjct: 821  GQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGP 852



 Score =  298 bits (763), Expect = 3e-80
 Identities = 172/412 (41%), Positives = 204/412 (49%), Gaps = 47/412 (11%)

Query: 1115 PGKKGDKGQIGPTGEVGSRGPPGK--IGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYR 1172
            PG +  +G+  P    GS  P  +   G  GPKG  G RG  G  G  G DG PG PG  
Sbjct: 82   PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLP 141

Query: 1173 GHQGQPGPSGLPG------PKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGY 1226
            G  G PGP G PG      P+   GY  + +  +  PGP G  GP G  G  G PG +G+
Sbjct: 142  GPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGF 201

Query: 1227 KGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGL 1286
            +G  G PG  GA+G  GP G PG  G+ G  GE G  G  G++G PGP G  G+PG  GL
Sbjct: 202  QGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGL 261

Query: 1287 LGPKGIQGYHGADGISGNPGKIGPPGKQGLP---------GIRGGPGRTGLAGAPGPPGV 1337
             G KG +G+ G DG  G+ G  GP G+ G P         G RG PG  G  GAPGP G 
Sbjct: 262  PGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGA 321

Query: 1338 KGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQ-------------------- 1377
            +G+ G  G+ G  GP G  G PG PG  G +G  G QG +                    
Sbjct: 322  RGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGA 381

Query: 1378 -GPCGDPGLKGQPGEYGVQ---GLTGFQGFPGPKGPEGDAGIVGISGPKGPIGH------ 1427
             GP G+PG  GQPG  G     G+ G  GFPG +GP G  G  G  GPKG  G       
Sbjct: 382  AGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGS 441

Query: 1428 RGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPR 1479
            +G+TG  G  G +G  G  GP GE+G RG  G  GP G PGPPG  G PG R
Sbjct: 442  KGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSR 493


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score =  924 bits (2389), Expect = 0.0
 Identities = 550/1315 (41%), Positives = 672/1315 (51%), Gaps = 120/1315 (9%)

Query: 492  GDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGEK 551
            G  GP GP GP G+ G  G  GP G PG  G+PG  G  G +GP+G PG  PG+   GE 
Sbjct: 213  GSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPG-KPGED--GEP 269

Query: 552  GDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNP 611
            G  G  G +G  G  G +G  G PGLPGL G +G  G  G  G  G PG +G AGP G  
Sbjct: 270  GRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPM 329

Query: 612  GPKGAQGFIGSPGEAGQLGPE---GERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSP 668
            G  G  G  G PGE G+LGP+   G+RG  G+ GK G  G  G PG  G  G  G+ G  
Sbjct: 330  GAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEA 389

Query: 669  GLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEP 728
            G  G  GP G  G RG  GP GP+G  G+PG +G  G  G  G  G  G  G  G  G P
Sbjct: 390  GPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPP 449

Query: 729  GYPGDKGAVGL---------PGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIP 779
            G PG +G+ G          PG PG +G++GP G+ G  G+QGP GPPG EG  G  G P
Sbjct: 450  GSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDP 509

Query: 780  GQNGPEGP---KGLLGNRGPPGP---PGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEP 833
            G  GP GP   +G  GNRG PG    PG KG QGE GP+G+ G  G +G PG+ G  G P
Sbjct: 510  GTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLP 569

Query: 834  GPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYP 893
            G  GL G  G QG  GK+   GP+G PGE G  G  G  G RG PG +G  G KG  G P
Sbjct: 570  GARGLTGNPGVQGPEGKL---GPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDP 626

Query: 894  GPP------GVP------------GPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLL 935
            G P      GVP            GP GP+G PG  G RG  G  GP G +G  GP G  
Sbjct: 627  GKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPP 686

Query: 936  GEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLR 995
            GE G  G +G  GD G  GP G  G+ GNPGER   G+PG+ GLPG  G  G  G  G +
Sbjct: 687  GEGGKPGDQGVPGDPGAVGPLGPRGERGNPGER---GEPGITGLPGEKGMAGGHGPDGPK 743

Query: 996  GLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGD---VGTAGSVGGTGEPGLRGEPGAP 1052
            G  G  G PG+ G  G  G  GE G+ G PG KGD   +G  G+ G  G  G RG PG  
Sbjct: 744  GSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPL 803

Query: 1053 GEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQR 1112
            G  G  G  G KG PG RGL G  G +G  G  G  GP G  G  G  GP+G  G+ G+ 
Sbjct: 804  GPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEP 863

Query: 1113 GRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYR 1172
            G PG+KGD G  GP G  GS GP G  G  G KG RGT+         GP G  G PG  
Sbjct: 864  GEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQ---------GPPGATGFPGSA 914

Query: 1173 GHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGV 1232
            G  G PGP+G PGP G  G PG++    GPPG RG+PG  G  G+RG  G  G  G  G 
Sbjct: 915  GRVGPPGPAGAPGPAGPLGEPGKE----GPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGD 970

Query: 1233 PGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLL---GP 1289
            PG  G  G  GPPG  G  G++G+ G  G  G +G  G PGP+G PG  G  G     GP
Sbjct: 971  PGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGP 1030

Query: 1290 KGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGI 1349
             G  G  G++G  G PG  GP G  G PG  G  G  G  G PGP G+ GS G PG+PG 
Sbjct: 1031 PGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGP 1090

Query: 1350 QGPKGEQGLPGQPGIQ---------GKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGF 1400
             G  G+ G  G PG +         GKRG  G QG +G  GD G +G  G+ G +G TG 
Sbjct: 1091 VGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGL 1150

Query: 1401 QGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGP 1460
            QG PGP GP G+ G  GI GP GP G  G  GP G+EG  GP G  GP G +G  GE GP
Sbjct: 1151 QGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGP 1210

Query: 1461 QGPRGQPGPPGPPGAPGPRKQMDINAAIQALI---ESNTALQMESYQNTEVTLIDHSEE- 1516
            +GP G+PGPPGPPG PG      + AA+  ++   + +    +  +   +    D ++  
Sbjct: 1211 EGPPGEPGPPGPPGPPG-----HLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDKNKTD 1265

Query: 1517 --IFKTLNYLSNLLHSIKNPLGTRDNPARICKDLLNCEQKVSDGKYWIDPNLGCPSDAIE 1574
              +  TL  LS+ + ++++P G++ +PAR C DL  C      G+YWIDPN G   DAI+
Sbjct: 1266 PGVHATLKSLSSQIETMRSPDGSKKHPARTCDDLKLCHSAKQSGEYWIDPNQGSVEDAIK 1325

Query: 1575 VFCNFSAGGQTCLP--PVSVTKLEFGVGK------------------------------- 1601
            V+CN    G+TC+   P SV +  +   K                               
Sbjct: 1326 VYCNMET-GETCISANPSSVPRKTWWASKSPDNKPVWYGLDMNRGSQFAYGDHQSPNTAI 1384

Query: 1602 VQMNFLHLLSSEATHIITIHCLNTPRWTSTQTSGPGLPIGFKGWNGQIFKV--NTLLEPK 1659
             QM FL LLS EA+  IT  C N+  +   Q       +  KG N    K   N      
Sbjct: 1385 TQMTFLRLLSKEASQNITYICKNSVGYMDDQAKNLKKAVVLKGANDLDIKAEGNIRFRYI 1444

Query: 1660 VLSDDCKIQDGSWHKATFLFHTQEPNQLPVIEVQKLPHLKTERKYYIDSSSVCFL 1714
            VL D C  ++G+  K  F + TQ   +LP+I++  +    T++++ ++   VCF+
Sbjct: 1445 VLQDTCSKRNGNVGKTVFEYRTQNVARLPIIDLAPVDVGGTDQEFGVEIGPVCFV 1499



 Score =  705 bits (1819), Expect = 0.0
 Identities = 417/946 (44%), Positives = 498/946 (52%), Gaps = 112/946 (11%)

Query: 487  LRGPKGDTGPPGPPGPAGIPGPSGKRGP---RGIP------GPHGNP------GLPGLPG 531
            L GPKG+ G PG  G AG  GP G  GP   RG+P      GP G P      G+PG PG
Sbjct: 307  LEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPG 366

Query: 532  PKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLK------GHPGLPGLPGEQG 585
            P GP G PG S     PG KG+ G +G  GP G QG +G        G PGLPG  G  G
Sbjct: 367  PMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDG 426

Query: 586  IPGFAGNIGSPGYPGRQGLAGPEGNPGPKGA---QGFIGSPGE------AGQLGPEGERG 636
             PG  G  GSPG  G  G AGP G+PGP+G+   QG  G PG+       G+ GP+GE G
Sbjct: 427  TPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPG 486

Query: 637  IPGIR------GKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVG 690
              GI+      G++G +G +G PG  G  GP G  G+PG  G  G  G PG +G+ G  G
Sbjct: 487  PHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERG 546

Query: 691  PIGPA---------GIPGPMGLSGNKGL---PGIKGDKGEQGTAGELGEPGYPGDKGAVG 738
            P+G +         G PG  GL G +GL   PG++G +G+ G  G  GE G PG  G++G
Sbjct: 547  PVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIG 606

Query: 739  LPGPPGMRGKSGPSGQTGDPGLQGP---SGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRG 795
            + G PG  G  GP G +GDPG  G    +G PG  G PG  G  G +GP GP GL G RG
Sbjct: 607  IRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERG 666

Query: 796  PPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETG 855
              GPPG  G QG  GP G  GE    GKPG +G  G+PG  G  G  G++GN G+ GE G
Sbjct: 667  EQGPPGPTGFQGLPGPPGPPGE---GGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPG 723

Query: 856  PVGLPGEVGMTGSIGEKGERGSPGPLGP------------QGEKGVMGYPGPP------- 896
              GLPGE GM G  G  G +GSPGP G              GE+G+ G PGP        
Sbjct: 724  ITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIG 783

Query: 897  --------------GVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQG 942
                          G+PGP+GP G  G  G +G PG +G  G  GSRG  G  GE G  G
Sbjct: 784  EKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTG 843

Query: 943  AKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVG 1002
            A G  G QG  G  G+ G+ G PG++G  G PG QGL GS G  G  G PGL+G +G  G
Sbjct: 844  AVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQG 903

Query: 1003 PPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDG 1062
            PPG  G    PG+ G  G  G  GA G  G  G  G  G PGLRG+PG+ G  G +G  G
Sbjct: 904  PPGATGF---PGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAG 960

Query: 1063 LKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKG 1122
              G PG +G PGEDG+ G  G PG  G  G+ G  G+PG  G  G+P   G PG  G  G
Sbjct: 961  PPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMP---GLPGPAGTPG 1017

Query: 1123 QIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSG 1182
            ++GPTG  G +GPPG +G  G  G  G  G  G  G  G  G  G  G RG +G PGP+G
Sbjct: 1018 KVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAG 1077

Query: 1183 LPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQ 1242
            LPG +G            G PGP G P   GD G+RG+PG+ G  G  G  G RG  G Q
Sbjct: 1078 LPGSQGAP----------GTPGPVGAP---GDAGQRGDPGSRGPIGPPGRAGKRGLPGPQ 1124

Query: 1243 GP---PGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGAD 1299
            GP    G+ GD+G++G KG RG  G +G  G PGP+G+ G  G+ G  GP+G  G  G  
Sbjct: 1125 GPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPS 1184

Query: 1300 GISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPG 1345
            G  GNPG +GP G    PG+RG  G  G  G PG PG  G  G PG
Sbjct: 1185 GKEGNPGPLGPIGP---PGVRGSVGEAGPEGPPGEPGPPGPPGPPG 1227



 Score =  667 bits (1722), Expect = 0.0
 Identities = 398/896 (44%), Positives = 462/896 (51%), Gaps = 88/896 (9%)

Query: 655  DFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKG 714
            +FG RG  G  G PGLV     P   G+RG  GP GP    G  GP G  G KG PG +G
Sbjct: 106  NFG-RGRKGQKGEPGLV-----PVVTGIRGRPGPAGP---PGSQGPRGERGPKGRPGPRG 156

Query: 715  DKGEQGTAGELGEPGYPGDKGAVGLPGPPGMR-----------GKSGPSGQTG-DPGLQG 762
             +G  G  G  G+PG PG  G    PGP G+             KSG   Q G  PG  G
Sbjct: 157  PQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVG 216

Query: 763  PSGPPGPEGFPGD------IGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFG 816
            P GP GP+G  G        G PG+ G  GP G +G+RGP GPPG  G  GE G  G  G
Sbjct: 217  PVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPG 276

Query: 817  ELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMT---GSIGEKG 873
            E+G  G PG +G+ G PG  GLKG  G +G  G  GE G  G  GE G T   G++G  G
Sbjct: 277  EVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLG 336

Query: 874  ERGSPGP---LGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPP------------G 918
             RG PG    LGPQG  G  G  G PG PGP+GPLG+PG  G  G P            G
Sbjct: 337  PRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARG 396

Query: 919  SQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQG 978
             +GP+GQRG  GP G +G  G+ GA G  G  G +GP G  G +G PG  G  G PG QG
Sbjct: 397  PEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQG 456

Query: 979  LPGSTGDRGLPGEPGLRGLQGDVGP---PGEMGMEGPPGTEGESGLQGEPGAKGDVGTAG 1035
              G  G RG PG+PG+ G +G+ GP   PG  G++GP G  GE G +G  G  G VG  G
Sbjct: 457  STGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPG 516

Query: 1036 SVGGTGEPGLRGEPGA---PGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGI----- 1087
             VG  G PG RG PG+   PG +G QG+ G  G  G +G  G+ G  GE GLPG      
Sbjct: 517  PVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTG 576

Query: 1088 ----------IGPLGRSGQTGLPGPEGIVGI---PGQRGRPGKKGDKGQIGPTGEVGSRG 1134
                      +GPLG  G+ G PGP G +GI   PG  G PG KG  G  G  GE G+ G
Sbjct: 577  NPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAG 636

Query: 1135 PPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPG 1194
             PG+ G  G  G  G  G VG  GL G  GE G PG  G QG PGP   PGP GE G PG
Sbjct: 637  VPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGP---PGPPGEGGKPG 693

Query: 1195 EDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQ 1254
            +     G PG  G  GP+G +GERG PG  G  G  G+PG +G  G  GP G  G  G  
Sbjct: 694  DQ----GVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPS 749

Query: 1255 GLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQ 1314
            G  G+ G  G +G  G  G +G PG  G +G +G KG +G  G DG  G PG +GPPG  
Sbjct: 750  GTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPA 809

Query: 1315 GLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQ 1374
            G  G +G PG  GL G PG  G  GS G  G  G  G  G QG  GQPG++G+ G  G +
Sbjct: 810  GPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQK 869

Query: 1375 GDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGIS---GPKGPIGHRGNT 1431
            GD G  G  GL G PG +G  G+ G +G  G +GP G  G  G +   GP GP G  G  
Sbjct: 870  GDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPA 929

Query: 1432 GPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQP---------GPPGPPGAPGP 1478
            GPLG  G  GP G  G  G  G  G+ GP GP G P         G PGP G PGP
Sbjct: 930  GPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGP 985



 Score =  504 bits (1299), Expect = e-142
 Identities = 310/739 (41%), Positives = 361/739 (48%), Gaps = 121/739 (16%)

Query: 843  GDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPI 902
            G   N G+ G  G  G PG V +   I     RG PGP GP G +G  G  GP G PGP 
Sbjct: 102  GGNTNFGR-GRKGQKGEPGLVPVVTGI-----RGRPGPAGPPGSQGPRGERGPKGRPGPR 155

Query: 903  GPLGLPGHVGARGPPGSQGPKGQRGSRGPDGL---------------------------- 934
            GP G+ G  G  G PG+ GP G     GPDGL                            
Sbjct: 156  GPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSV 215

Query: 935  -----LGEQGIQGAK---------GEKGDQ------GKRGPHGLIGKTGNPGERGFQGKP 974
                  G QG+QG +         GE GD       G RGP G  GK G  GE G  G P
Sbjct: 216  GPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNP 275

Query: 975  GLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTA 1034
            G  G  GS G RG PG PGL GL+G     G  G+EGP G  G  G +GE G  G +G  
Sbjct: 276  GEVGFAGSPGARGFPGAPGLPGLKGH---RGHKGLEGPKGEVGAPGSKGEAGPTGPMGAM 332

Query: 1035 GSVGGTGEPGLRGE---PGAPGEEGLQGKDGLK------GVPGGRGLPGEDGEKGEMGLP 1085
            G +G  G PG RG     GAPG+ G  G  G        G+PG  G PG  G KGE G  
Sbjct: 333  GPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPT 392

Query: 1086 GIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPK 1145
            G  GP G  GQ G  GP G VG PG  G  G  G  G  GPTG  G+ GPP   G +GP 
Sbjct: 393  GARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPP---GSAGPP 449

Query: 1146 GARGTRGAVGHLGLMGPDGEPGIPGYRGH---QGQPGPSGLPGPKGEKGYPGEDSTVLGP 1202
            G+ G +G+ G  G+ G  G+PG+PG++G    +G+PGP G+ GP G    PGE+    G 
Sbjct: 450  GSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGP---PGEE----GK 502

Query: 1203 PGPRGEP---GPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGP--------------- 1244
             GPRG+P   GP G  GERG PG  G+ G  G+PG +GA G++GP               
Sbjct: 503  RGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGR 562

Query: 1245 PGEPGDQGEQGLKGE---RGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGI 1301
            PGEPG  G +GL G    +G EG  G  GAPG  G+PG PG  G+ G  G  G  G  G 
Sbjct: 563  PGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGS 622

Query: 1302 SGNPGKIGPPGKQGLPGIRGGPGRTGLA------------------GAPGPPGVKGSSGL 1343
            SG+PGK G  G  G+PG RG PG+ G                    G PGP G +G  G 
Sbjct: 623  SGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGP 682

Query: 1344 PGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGV---QGLTGF 1400
            PG PG  G  G+QG+PG PG  G  G RG +G+ G  G+PG+ G PGE G+    G  G 
Sbjct: 683  PGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGP 742

Query: 1401 QGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGP 1460
            +G PGP G  GD G  G+ G  G  G  G  GP G  G IG  G  G  G  G RG  GP
Sbjct: 743  KGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGP 802

Query: 1461 QGPRGQPGPPGPPGAPGPR 1479
             GP G  GP G  G PGPR
Sbjct: 803  LGPPGPAGPTGEKGEPGPR 821



 Score =  317 bits (813), Expect = 5e-86
 Identities = 193/476 (40%), Positives = 230/476 (48%), Gaps = 66/476 (13%)

Query: 1067 PGGRGLPGEDGEKGEMGLPGII----GPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDK- 1121
            PGG       G KG+ G PG++    G  GR G  G PG +G  G  G +GRPG +G + 
Sbjct: 100  PGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQG 159

Query: 1122 --GQIGPTGEVGSRGP------------------------------------PGKIGKSG 1143
              G+ G  G+ G+ GP                                    PG +G  G
Sbjct: 160  IDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVG 219

Query: 1144 PKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDST----- 1198
            P+G +G +G  G  G  GP GEPG PG  G  G  GP G PG  GE G PG +       
Sbjct: 220  PRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVG 279

Query: 1199 VLGPPGPR---GEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQG 1255
              G PG R   G PG  G +G RG  G EG KG VG PG +G  G  GP G  G  G +G
Sbjct: 280  FAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRG 339

Query: 1256 LKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQG 1315
            + GERG  G +G  G  G  G PG PG  G LG  G  G+ G  G+ G  G  G  G +G
Sbjct: 340  MPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEG 399

Query: 1316 LPGIRGGPGRTGLAGAPGPPGVKGSSGLP------GSPGIQGPKGEQGLPGQPGIQGKRG 1369
              G RG  G  G  G+PG PG  G+ G P      GSPG  GP G  G PG PG QG  G
Sbjct: 400  PQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTG 459

Query: 1370 HRGAQGDQGPCGDPGL------KGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKG 1423
             +G +G  G  G PG       KG+PG +G+QG  G  G  G +GP GD G V   GP G
Sbjct: 460  PQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTV---GPPG 516

Query: 1424 PIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPR 1479
            P+G RG  G  G  G  G  G  G +GE+G  G +GP+G +G PG PG PG PG R
Sbjct: 517  PVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGAR 572


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score =  907 bits (2344), Expect = 0.0
 Identities = 548/1352 (40%), Positives = 673/1352 (49%), Gaps = 150/1352 (11%)

Query: 488  RGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHG----------------NPGLPGLPG 531
            RGP+G+ GPPGPPG  G  GP+G  GP G PGP G                 PG  GL G
Sbjct: 38   RGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMG 97

Query: 532  PKGPKG------DPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQG 585
            P+GP G        GF      PGE G  G +G  GP G  G  G  GHPG PG PGE+G
Sbjct: 98   PRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERG 157

Query: 586  IPGFAGNIGSPGYPG---------RQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERG 636
            + G  G  G PG PG           GL G +G PG  G +G  G+PGE G  G  G RG
Sbjct: 158  VVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARG 217

Query: 637  IPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAG 696
            +PG RG+ G  G  G  G  G  GP G     G +G  GPPGFPG  G  G +G +G AG
Sbjct: 218  LPGERGRVGAPGPAGARGSDGSVGPVG---PAGPIGSAGPPGFPGAPGPKGEIGAVGNAG 274

Query: 697  IPGPMGLSGNKGLPGIKG------DKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSG 750
              GP G  G  GLPG+ G      + G  G  G  G  G PG  GA GLPGP G+ G  G
Sbjct: 275  PAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVG 334

Query: 751  PSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGP------------KGLLGNRGPPG 798
             +G TG  GL G  GP G +G  G+ G PG  GP+GP             G  G+ GPPG
Sbjct: 335  AAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPG 394

Query: 799  PPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVG 858
            PPGL+G+ G  G  GA G  G  G PG +G +G   P G++G  GD G  G+ G  GP G
Sbjct: 395  PPGLRGSPGSRGLPGADGRAGVMGPPGSRGASG---PAGVRGPNGDAGRPGEPGLMGPRG 451

Query: 859  LPGEVGMTGSIGEKGE------RGSPGPLGP---QGEKGVMGYPGPPGVPGPIGPLGLPG 909
            LPG  G  G  G++G        G PGP+GP   +GE G +G+PGP G  G  G  G  G
Sbjct: 452  LPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKG 511

Query: 910  HVG---ARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPG 966
            H G   ARG PG  G  G +G  GP G+ G +G QG  G  G QG  GP G  G+ G PG
Sbjct: 512  HAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPG 571

Query: 967  ERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVG------PPGEMGMEGPPG------ 1014
            ERG  G+ GL G  G  G+RG PGE G  G  G +G      PPG  G +G PG      
Sbjct: 572  ERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVG 631

Query: 1015 TEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPG 1074
            T G SG  G PG +G  G  G  G  GEPGLRGE G PG +G +G  G  G PG  G  G
Sbjct: 632  TAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATG 691

Query: 1075 EDGEKGEMGLPGIIGPLG---RSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVG 1131
            + GE G  G  G  GP G     G+ G  GP G  G  G  G+PG KG++G  GP GE G
Sbjct: 692  DRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENG 751

Query: 1132 SRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKG 1191
              GP G +G +GP G  G  G  G  G  GP G  G PG  G  G PGPSG+ GP G  G
Sbjct: 752  VVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPG 811

Query: 1192 YPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQ 1251
              G++    G  GPRG+ GPV   G  GE GA G  G  G  G  G  G  GPPG PG Q
Sbjct: 812  PAGKE----GLRGPRGDQGPV---GRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQ 864

Query: 1252 GEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGA------------D 1299
            G  G  G  G  G++G++G PG +G  G PG  G+ GP G +G  GA             
Sbjct: 865  GLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEA 924

Query: 1300 GISGNPGKIGPPGKQGLP---GIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQ 1356
            G  GNPG  GPPG+ G P   G RG PG  G  GA G PG  G  G  G  G +G  G  
Sbjct: 925  GRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPS 984

Query: 1357 GLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIV 1416
            G  G  G  G RG  G QG +G  G+PG KG  G  G++G  G QG PG  G  GD G  
Sbjct: 985  GPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAP 1044

Query: 1417 GISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAP 1476
            G  GP GP G  G +GP G++G  G  G  GP G +G +G  GP GP G PGPPGPPG  
Sbjct: 1045 GSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVS 1104

Query: 1477 GPRKQMDINAAIQALIESNTALQMESYQNTEVTLIDHSEEIFKTLNYLSNLLHSIKNPLG 1536
            G       +       +  +A           +L     E+  TL  L+N + ++  P G
Sbjct: 1105 GGGYDFGYDGDFYRADQPRSA----------PSLRPKDYEVDATLKSLNNQIETLLTPEG 1154

Query: 1537 TRDNPARICKDLLNCEQKVSDGKYWIDPNLGCPSDAIEVFCNFSAGGQTCL--PPVSV-- 1592
            +R NPAR C+DL     + S G YWIDPN GC  DAI+V+C+FS  G+TC+   P ++  
Sbjct: 1155 SRKNPARTCRDLRLSHPEWSSGYYWIDPNQGCTMDAIKVYCDFST-GETCIRAQPENIPA 1213

Query: 1593 ----------------------TKLEFGVGKV-------QMNFLHLLSSEATHIITIHCL 1623
                                  ++ E+ V  V       Q+ F+ LL++ A+  IT HC 
Sbjct: 1214 KNWYRSSKDKKHVWLGETINAGSQFEYNVEGVTSKEMATQLAFMRLLANYASQNITYHCK 1273

Query: 1624 NTPRWTSTQTSGPGLPIGFKGWNG--QIFKVNTLLEPKVLSDDCKIQDGSWHKATFLFHT 1681
            N+  +   +T      +  +G N    + + N+     VL D C  +   W K    + T
Sbjct: 1274 NSIAYMDEETGNLKKAVILQGSNDVELVAEGNSRFTYTVLVDGCSKKTNEWGKTIIEYKT 1333

Query: 1682 QEPNQLPVIEVQKLPHLKTERKYYIDSSSVCF 1713
             +P++LP +++  L     ++++++D   VCF
Sbjct: 1334 NKPSRLPFLDIAPLDIGGADQEFFVDIGPVCF 1365



 Score =  691 bits (1784), Expect = 0.0
 Identities = 412/943 (43%), Positives = 480/943 (50%), Gaps = 82/943 (8%)

Query: 487  LRGPKGDTGPPGPPGPAGIPGPSG---KRGPRGIPGPHGNPGLPGLP------------G 531
            L G KG  G PG  G  G PG +G   + G RG+PG  G  G PG              G
Sbjct: 185  LDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVG 244

Query: 532  PKGPKGDPGFSPGQP-VPGEKGDQGLSGLMGPPGMQGDKGLKGHPGL------PGLPGEQ 584
            P GP G  G  PG P  PG KG+ G  G  GP G  G +G  G PGL      PG PG  
Sbjct: 245  PAGPIGSAG-PPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGAN 303

Query: 585  GIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKK 644
            G+ G  G  G PG  G  GL GP G PGP GA G  G+ G  G+ GP G +G  G +G+ 
Sbjct: 304  GLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEP 363

Query: 645  GFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLS 704
            G  G QG PG  G+ G  G +G     G  GPPG PGLRGS G  G  G  G  G MG  
Sbjct: 364  GSAGPQGPPGPSGEEGKRGPNGE---AGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPP 420

Query: 705  GNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPS 764
            G++G  G  G +G  G AG  GEPG  G +G  G PG  G  GK GP G  G  G  GP 
Sbjct: 421  GSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPI 480

Query: 765  GPPGPEGFPGDIGI---------PGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAF 815
            GP G  G PG+IG          PG+NG +G  GL G RG PGP G  G QG  GP G  
Sbjct: 481  GPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQ 540

Query: 816  GELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGE---------TGPVGLPGEVGMT 866
            G  G +G PG  G+ G PGP G  GEVG  G  G  GE          G  G PGE G  
Sbjct: 541  GGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAA 600

Query: 867  GSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQ- 925
            G  G  G RG  GP GP G KG  G  G  G  GP GP GLPG  GA G PG +G KG+ 
Sbjct: 601  GPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEP 660

Query: 926  -----------RGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGER------ 968
                        G+RG  G +G  G  GA G++G+ G  GP G  G  G+PGER      
Sbjct: 661  GLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPA 720

Query: 969  ---GFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEP 1025
               GF G  G  G PG+ G+RG  G  G  G+ G  GP G  G  GP G  G +G +G+ 
Sbjct: 721  GPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDG 780

Query: 1026 GAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLP 1085
            G  G  G  G+ G TG PG  G  G PG  G  GK+GL+G  G +G  G  GE G +G P
Sbjct: 781  GPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPP 840

Query: 1086 GIIGPLGRSGQT------GLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKI 1139
            G  G  G SG+       G PGP+G++G PG  G PG +G++G  G  G VG    PG +
Sbjct: 841  GFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGE---PGPL 897

Query: 1140 GKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTV 1199
            G +GP GARG  GAVG  G+ G  GE G  G  G+ G PG  G PG KGE+GYPG    V
Sbjct: 898  GIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPV 957

Query: 1200 --LGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLK 1257
               G PGP G  GP G  G RGE G  G  G  G  G RG +G QG  G+ G+ GE+G +
Sbjct: 958  GAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPR 1017

Query: 1258 GERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLP 1317
            G  G +G+ G +G PG +G  G  G  G +GP G +G  G  G +G  G+ G PG  G  
Sbjct: 1018 GLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPA 1077

Query: 1318 GIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPG 1360
            GIRG  G  G AG PGPPG       PG PG+ G   + G  G
Sbjct: 1078 GIRGPQGHQGPAGPPGPPGP------PGPPGVSGGGYDFGYDG 1114



 Score =  600 bits (1547), Expect = e-171
 Identities = 359/827 (43%), Positives = 408/827 (49%), Gaps = 89/827 (10%)

Query: 719  QGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGP------------ 766
            Q    E    G  GD+G  G  GPPG  G+ G  G TG PG  GP GP            
Sbjct: 23   QSLQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYD 82

Query: 767  -------------------------PGPEGFPGDIGIPGQ---------NGPEGPKGLLG 792
                                     PGP+GF G  G PG+          GP GP G  G
Sbjct: 83   GKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAG 142

Query: 793  NRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQK---------GYAGEPGPEGLKGEVG 843
              G PG PG  G +G  GP GA G  G  G PG K         G  G+PG  G+KGE G
Sbjct: 143  EDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPG 202

Query: 844  DQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIG 903
              G  G  G+TG  GLPGE G  G+ G  G RGS G +GP G  G +G  GPPG PG  G
Sbjct: 203  APGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPG 262

Query: 904  PLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTG 963
            P G  G VG  GP G  GP+G+ G  G  G +G  G  GA G  G +G  G  G+ G  G
Sbjct: 263  PKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPG 322

Query: 964  NPGERGFQGKPGLQGLPGSTGDRGLPGEP---GLRGLQGDVGPPGEMGMEGPPGTEGESG 1020
             PG RG    PG  G  G+TG RGL GEP   G +G  G+ G PG  G +GPPG  GE G
Sbjct: 323  LPGPRGI---PGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEG 379

Query: 1021 LQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKG 1080
             +G  G  G  G  G  G  G PG RG PGA G  G+ G  G +G  G  G+ G +G+ G
Sbjct: 380  KRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAG 439

Query: 1081 EMGLPGIIGPLGRSGQTGLPGP---EGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPG 1137
              G PG++GP G  G  G  GP   EG VG+PG  GRP         GP G  G+RG PG
Sbjct: 440  RPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRP---------GPIGPAGARGEPG 490

Query: 1138 KIGKSGPKGAR---GTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPG 1194
             IG  GPKG     G  G  GH GL G  G PG  G  G QG PGP G+ G KGE+G P 
Sbjct: 491  NIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPP- 549

Query: 1195 EDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQ 1254
                  GPPG +G PGP G  GE G+PG  G  G  G+PG  G  G++GPPGE    G  
Sbjct: 550  ------GPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGE---SGAA 600

Query: 1255 GLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQ 1314
            G  G  GS G  G  G  G  G+PG+ G  G  GP G  G  G  G +G PG  G  G+ 
Sbjct: 601  GPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEP 660

Query: 1315 GLPGIRGGPGRTGLAGAP---GPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHR 1371
            GL G  G PGR G  GAP   G PG  G++G  G  G  GP G  G  G PG +G+ G  
Sbjct: 661  GLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPA 720

Query: 1372 GAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNT 1431
            G  G  GP G  G  G  GE G +G  G  G  GP GP G AG  G +GP GP G RG+ 
Sbjct: 721  GPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDG 780

Query: 1432 GPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGP 1478
            GP G  G  G  GRTGP G  G  G  GP GP G+ G  GP G  GP
Sbjct: 781  GPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGP 827



 Score =  266 bits (681), Expect = 1e-70
 Identities = 156/384 (40%), Positives = 181/384 (47%), Gaps = 54/384 (14%)

Query: 1141 KSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGE----- 1195
            + GP G RG RG           G PG PG  G  G  GP G PGP G  G  G      
Sbjct: 31   RKGPAGDRGPRGE---------RGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQY 81

Query: 1196 DSTVLG-PPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQ 1254
            D   +G  PGP G  GP G  G  G PG +G++G  G PG  G TG  G  G  G  G+ 
Sbjct: 82   DGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKA 141

Query: 1255 GLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQ 1314
            G  G  G  G  G++G  GP G  G PG  GL G KGI+G++G DG+ G PG  G  G+ 
Sbjct: 142  GEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEP 201

Query: 1315 GLPGIRGGPGRTGL---------AGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQ 1365
            G PG  G PG+TG           GAPGP G +GS G  G  G  GP G  G PG PG  
Sbjct: 202  GAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAP 261

Query: 1366 GKRGHRGAQGDQGPCGDPGLKGQ------------------------------PGEYGVQ 1395
            G +G  GA G+ GP G  G +G+                              PG  G  
Sbjct: 262  GPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAP 321

Query: 1396 GLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFR 1455
            GL G +G PGP G  G  G  G+ G  GP G +G +G  G  G  GP G  GP GE+G R
Sbjct: 322  GLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKR 381

Query: 1456 GETGPQGPRGQPGPPGPPGAPGPR 1479
            G  G  G  G PGPPG  G+PG R
Sbjct: 382  GPNGEAGSAGPPGPPGLRGSPGSR 405


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score =  896 bits (2315), Expect = 0.0
 Identities = 559/1378 (40%), Positives = 674/1378 (48%), Gaps = 171/1378 (12%)

Query: 485  EYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSP- 543
            +   GP G  GP G  GP+G PGP G  G  G PGP G PG+PG+ G +GP G     P 
Sbjct: 388  QQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPF 447

Query: 544  --------GQPVP------------------GEKGDQGLSGLMGP------PGMQGDKGL 571
                    G PV                   G  G  GL+G  GP      PG++G++G 
Sbjct: 448  QFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGA 507

Query: 572  KGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGP 631
            +G  G  GL G  G PG  G +G PG  G +GL G  G  G +G  G  G PGE GQ G 
Sbjct: 508  EGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGD 567

Query: 632  EGERGIPGIRGKKGFKGRQGFPG---DFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGP 688
             G  G PG  G+ G +G +G PG     G+ GP GL G  G  G TG PG  G+ G+ G 
Sbjct: 568  FGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGA 627

Query: 689  VGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPG---------------- 732
             G +GP G PGP G  GN G  G+ G +G  GT GE G PG PG                
Sbjct: 628  KGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGH 687

Query: 733  -----DKGAVGLPG---PPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPG---DIGIPGQ 781
                 +KGA G PG   PPG  G  G  G +G+ GLQG  G  G +GFPG   D+G+ G 
Sbjct: 688  EGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGD 747

Query: 782  NGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGE 841
             G  G  G  G  GP GP G  G  GEEGP G+ GE G  G PG  GY G PGP+G  G 
Sbjct: 748  QGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGF 807

Query: 842  VGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGP 901
             G  G IG+ G++G  G PG  G  G  G +GERG PG  G  G KG +G  G PG+PG 
Sbjct: 808  PGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGE 867

Query: 902  IGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGK 961
                GLPG    +GPPG  GPKG  G +G DG  G  G +G  G +G  G  GP G++G 
Sbjct: 868  ---KGLPG---LQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGP 921

Query: 962  TGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGL 1021
             G  GE G  G+ G  G PG  G++GLPG  G  G +G++GPPG +G EGP G  G  G 
Sbjct: 922  QGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGP 981

Query: 1022 QGEPG------AKGDVGTAGSVGGTGEPGLRGEPGA------PGEEGLQGKDGLKGVPGG 1069
            +G PG       KGD G  G VG  G PG RG  G       PG+ G +G  G  G  G 
Sbjct: 982  KGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGS 1041

Query: 1070 RGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGE 1129
            RG  G  G  G+ G+PG +GPLG  G  G  G EG  G  G  G  G KGDKG  GP G+
Sbjct: 1042 RGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQ 1101

Query: 1130 VGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGE 1189
             G RGP G  G  G  GA+G RG  G   L G  G+ G+ G+ G  G PG  GLPGP GE
Sbjct: 1102 PGIRGPAGHPGPPGADGAQGRRGPPG---LFGQKGDDGVRGFVGVIGPPGLQGLPGPPGE 1158

Query: 1190 KGYPGEDSTV--LGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGE 1247
            KG  G+  ++   G PGPRG  GP G +G  G PG  G  G VG  G RG  G  GPPG 
Sbjct: 1159 KGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGA 1218

Query: 1248 PG------DQGEQGLKGERGSEGNKGKKGAPGPSGK---------------PGIPGLQGL 1286
            PG      D GE+G  G  G+ G  GKKG PG  G                PG PG+ G+
Sbjct: 1219 PGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGI 1278

Query: 1287 LGPKGIQ------GYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGA------PGP 1334
             G  G +      G  G  G SG PG  GPPGK+G  G  G  GR G  GA       GP
Sbjct: 1279 DGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGP 1338

Query: 1335 PGVKGSSGLPGSPGIQGPKGEQGLP---GQPGIQGKRGHRGAQGDQGPCGDPGLKGQ--- 1388
            PG  G  G  G PG  GP+G +G+P   G+PG+ G  G  G  G  GP G PGLKG    
Sbjct: 1339 PGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGP 1398

Query: 1389 PGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGP 1448
             GE G  GL G  G PG  G +GD G+ G+ GP GP G  G  GP+G  G  GP G  GP
Sbjct: 1399 KGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGP 1458

Query: 1449 RGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQMDINAAIQALIESNTALQMESYQNTEV 1508
             G+KG +G  G  GPRG  GP GPPG PG            A  E +   +   +    +
Sbjct: 1459 LGQKGSKGSPGSMGPRGDTGPAGPPGPPG------------APAELHGLRRRRRFVPVPL 1506

Query: 1509 TLIDHS-EEIFKTLNYLSNLLHSIKNPLGTRDNPARICKDLLNCEQKVSDGKYWIDPNLG 1567
             +++   EE+  +L  LS  L  ++ P GT + P  +C +L      + DG+YWIDPN G
Sbjct: 1507 PVVEGGLEEVLASLTSLSLELEQLRRPPGTAERPGLVCHELHRNHPHLPDGEYWIDPNQG 1566

Query: 1568 CPSDAIEVFCNFSAGGQTCLPP---VSVTKL-------------EFGVGK---------- 1601
            C  D+  VFCNF+AGG+TCL P     + KL              F  GK          
Sbjct: 1567 CARDSFRVFCNFTAGGETCLYPDKKFEIVKLASWSKEKPGGWYSTFRRGKKFSYVDADGS 1626

Query: 1602 ----VQMNFLHLLSSEATHIITIHCLNTPRWTSTQTSGPGLPIGFKGWNGQ--IFKVNTL 1655
                VQ+NFL LLS+ A    T  C N   W    T        F G NG+   F   T 
Sbjct: 1627 PVNVVQLNFLKLLSATARQNFTYSCQNAAAWLDEATGDYSHSARFLGTNGEELSFNQTTA 1686

Query: 1656 LEPKVLSDDCKIQDGSWHKATFLFHTQEPNQLPVIEVQKLPHLKTERKYYIDSSSVCF 1713
                V  D C+++ G   K  F F +     LP+ +V      +T +K+  +   VCF
Sbjct: 1687 ATVSVPQDGCRLRKGQ-TKTLFEFSSSRAGFLPLWDVAATDFGQTNQKFGFELGPVCF 1743



 Score =  761 bits (1965), Expect = 0.0
 Identities = 458/1049 (43%), Positives = 544/1049 (51%), Gaps = 136/1049 (12%)

Query: 480  TMLEMEYLRGPKGDTGPPGP------PGPAGIPGPSGKRGPRGIPGPHGNPG-------- 525
            T L M+   GP G TG PGP      PG  G  G  G +GPRG+ GPHG PG        
Sbjct: 473  TQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRP 532

Query: 526  -------LPGLPGPKGPKGDPGFSPGQP-VPGEKGDQGLSGLMGPPGMQGDKGLKGHP-- 575
                   LPG  GPKG +G  G  PG P   G++GD G  G  GPPG  G++G +G P  
Sbjct: 533  GADGARGLPGDTGPKGDRGFDGL-PGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGP 591

Query: 576  ----------------------GLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGP 613
                                  G PG+ G  G PG  GN+G PG PG  G  G  G+ G 
Sbjct: 592  TGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGL 651

Query: 614  KGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVG- 672
             G QG IG+PGE G  G  G  G+PG  G  G  G +G  G+ G +GP G  G PG  G 
Sbjct: 652  PGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGP 711

Query: 673  ----GT-------------GPPGFPGLRGSVGPVGPIGPAGIPGP------------MGL 703
                GT             G  GFPG +G VG  G  G  G PGP             G 
Sbjct: 712  RGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQ 771

Query: 704  SGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGP 763
            +G +G PG  G+KG+ G  G  G PG PG KG++G PGP G  G+ G SG+TG PGL+G 
Sbjct: 772  AGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGE 831

Query: 764  SGPPGPEGFPGDIGIPGQNGPE------------GPKGLLGNRGPPGPPGLKGTQGEEGP 811
             GPPG  G  G  G  GQ GP+            G KGL G +GPPG PG KG  G +G 
Sbjct: 832  RGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGK 891

Query: 812  IGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGE------VGM 865
             G  G  G RG+ G +G  G PGP G+ G  G  G +G +GE GP G PG        G+
Sbjct: 892  DGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGL 951

Query: 866  TGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGL------PGHVGARGPPGS 919
             G  G KGE G PGPLG +G  G+ G+PGP G PG  GP GL      PG VGA G PG 
Sbjct: 952  EGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGE 1011

Query: 920  QGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGL 979
            +GP G  G  G  G  G +G  G  G+KG +G+RGP G  GK G PG  G  G PG  G 
Sbjct: 1012 RGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGP 1071

Query: 980  PGSTGDR---GLPGEPGLRGLQGDVGPPGEMGME------GPPGTEGESGLQGEP---GA 1027
             G  GD+   G PG  G +G +GD GPPG+ G+       GPPG +G  G +G P   G 
Sbjct: 1072 SGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQ 1131

Query: 1028 KGDVGTAGSVGGTGEPGLRGEPGAPGEEGL---QGKDGLKGVPGGRGLPGEDGEKGEMGL 1084
            KGD G  G VG  G PGL+G PG PGE+G     G  G  G PG RG  G  G +G  GL
Sbjct: 1132 KGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGL 1191

Query: 1085 PGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGP 1144
            PG +G  G  G+ G  G  G  G PG  G PG KGD G+ G +G  G+ GPPGK G  G 
Sbjct: 1192 PGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGE 1251

Query: 1145 KGARGTRGAVGHLGLMGPDGEP---GIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLG 1201
             GA+G+ G  G  G +GP G+P   GI G  G +G PG  G PGP G  G PG      G
Sbjct: 1252 DGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAP----G 1307

Query: 1202 PPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLK---G 1258
            PPG RG  G +G +G  GE GA+G  G  G PG  G  G +GPPG  G +G +G+    G
Sbjct: 1308 PPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVG 1367

Query: 1259 ERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPG 1318
            E G  G  G+ G PGP G  G+PGL+G  GPKG +G+ G  G+ G PG+ G  G QGLPG
Sbjct: 1368 EPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPG 1427

Query: 1319 IRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQG 1378
            ++G PG     G PGPPG  GS G PG PG+ GP G++G  G PG  G R      GD G
Sbjct: 1428 VQGPPGP---KGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPR------GDTG 1478

Query: 1379 PCGDPGLKGQPGE-YGVQGLTGFQGFPGP 1406
            P G PG  G P E +G++    F   P P
Sbjct: 1479 PAGPPGPPGAPAELHGLRRRRRFVPVPLP 1507



 Score =  724 bits (1870), Expect = 0.0
 Identities = 440/1026 (42%), Positives = 520/1026 (50%), Gaps = 94/1026 (9%)

Query: 531  GPKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFA 590
            G KG KG+P          EKG Q      GPPG  G +G+ G  G PG PG  G PG  
Sbjct: 373  GEKGAKGEPAVI-------EKGQQ----FEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPP 421

Query: 591  GNIGSPGYPGRQGLAGPEGN----PGPKGAQGFIGSPG-----------EAGQLGPEGER 635
            G  G PG PG  G+ GP G     P       F G P            +  QL  +G  
Sbjct: 422  GPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPP 481

Query: 636  GIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPA 695
            G  G+ G+ G  G  G PG  G+ G  G  G  GL G  GPPG  G  G  G  G  G  
Sbjct: 482  GPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLP 541

Query: 696  GIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGD---KGAVGLPGPPGMRGKSGPS 752
            G  GP G  G  GLPG+ G+KG++G  G +G+PG PG+   +GA G PGP G  G+ GP 
Sbjct: 542  GDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPR 601

Query: 753  GQTGDPGLQGPSGPPGPEGFPG------DIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQ 806
            G  G  G  GP+G PG  G  G      ++G PG+ GP G +G  G++G PGP GL GT 
Sbjct: 602  GLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTP 661

Query: 807  GEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMT 866
            GE+GP G  G  G  G  G  G+ G  GP G KG  G  G+ G  G  GP G+ G  G  
Sbjct: 662  GEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNR 721

Query: 867  GSIGEKGERGSPG------PLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQ 920
            G  GEKGE+G  G       +G +G++G  G PGP G  GP GP G  G  G  GPPGS 
Sbjct: 722  GLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSA 781

Query: 921  GPKGQRG---------SRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQ 971
            G KG+ G           GP G +G  G  G  GEKG  GK G  GL G+ G PG RG +
Sbjct: 782  GEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGER 841

Query: 972  GKPGLQGLPGSTGD---RGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAK 1028
            G+PG  G PG  GD    G PG PG +GL G  GPPG  G +GPPG +G+ G  G PG +
Sbjct: 842  GQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQR 901

Query: 1029 GDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGII 1088
            G++G  G  G          PG  G  G QGK G  G  G RG PG  G  GE GLPG+ 
Sbjct: 902  GELGFQGQTG---------PPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLE 952

Query: 1089 GPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGAR 1148
            G  G  G+ G PGP G  G  G RG PG KG  G  GPTG  G +GPPG +G +G  G R
Sbjct: 953  GREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGER 1012

Query: 1149 GTRGAVGHLGLMG------PDGEPGIPGYRGHQGQPGPSG---LPGPKGEKGYPGE---- 1195
            G  G  G +GL G      P G  G  G RG +G PGP+G   +PGP G  G PG     
Sbjct: 1013 GPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPS 1072

Query: 1196 ----DSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQ 1251
                D   +G PG +G  G  GD G  G+PG  G  GH G PG  GA G++GPPG  G +
Sbjct: 1073 GEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQK 1132

Query: 1252 GEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPP 1311
            G+ G++G  G  G  G +G PGP G+ G  G  G +GP G  G  G  G +G+ G  G P
Sbjct: 1133 GDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLP 1192

Query: 1312 GKQGLPGIRGGPGRTGLAGAPGPPGVK---------GSSGLPGSPGIQGPKGEQGLPGQP 1362
            G  G PG  G  G  G AG PGPPG           G  G  G  G  GP G++G PG+ 
Sbjct: 1193 GGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGED 1252

Query: 1363 GIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPK 1422
            G +G  G  G  GD GP GDPG+ G  G  G +G  G  G PGP G  G+ G  G  G +
Sbjct: 1253 GAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKR 1312

Query: 1423 GPIGHRGNTGPLGREGI------IGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAP 1476
            GP GH G  G  G +G        GP GRTGP G +G  G  GP+G RG PGP G PG  
Sbjct: 1313 GPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLL 1372

Query: 1477 GPRKQM 1482
            G   QM
Sbjct: 1373 GAPGQM 1378



 Score =  590 bits (1520), Expect = e-168
 Identities = 373/904 (41%), Positives = 433/904 (47%), Gaps = 161/904 (17%)

Query: 715  DKGEQGTAG-ELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGF- 772
            ++G+  T G +     YP        PG      K  P+        +GP G PGP+G  
Sbjct: 344  EEGDDSTMGPDFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVV 403

Query: 773  -----PGDIGIPGQNGPEGPKGL------------------------------------- 790
                 PG  G PG  GP GP GL                                     
Sbjct: 404  GPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQ 463

Query: 791  -----------LGNRGPPGP---------------PGLKGTQGEEGPIGAFGELGPRGKP 824
                       L  +GPPGP               PGLKG +G EGP G  G  GP G P
Sbjct: 464  AQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPP 523

Query: 825  GQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQ 884
            G+ G  G PG +G +G  GD G  G  G  G  GLPGE G  G  G  G+   PGP G  
Sbjct: 524  GRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQ---PGPPGED 580

Query: 885  GEKGVMGYPGPPGVPGPIGPLGLPGHVGARGP---PGSQGPKGQRGSRGPDGLLGEQGIQ 941
            GE+G  G PGP G  G  GP GL G  G+ GP   PG  G  G  G++G  G  GE G  
Sbjct: 581  GERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPP 640

Query: 942  GAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLP------GEPGLR 995
            G +G  G QG  GP GLI   G PGE+G  G PG+ GLPGS G  G P      GE G +
Sbjct: 641  GQQGNHGSQGLPGPQGLI---GTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQ 697

Query: 996  GLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAP--- 1052
            G  G  GPPG  G  G  GT G  GLQGE G KG+ G  G  G  G  G +G+PGAP   
Sbjct: 698  GPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPR 757

Query: 1053 GEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQR 1112
            GE+G +G  G  G  G  G PG  GEKG++G+PG+ G  GR      PGP+G +G PG  
Sbjct: 758  GEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGR------PGPKGSIGFPGPL 811

Query: 1113 GRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYR 1172
            G  G+KG  G+ G  G  G RGPPG  G+ G  GA G  G  G    +G DG PGIPG +
Sbjct: 812  GPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGD---VGQDGAPGIPGEK 868

Query: 1173 GHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGV 1232
            G  G  GP G PGPKG  G+ G+D    G PG  G+ G +G QG+ G PG  G  G  G 
Sbjct: 869  GLPGLQGPPGFPGPKGPPGHQGKD----GRPGHPGQRGELGFQGQTGPPGPAGVLGPQGK 924

Query: 1233 PGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGI 1292
             G  G  G++GPPG PG  GEQGL G  G EG KG+ G PGP GK G  GL+G  GPKG 
Sbjct: 925  TGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGG 984

Query: 1293 QGYHGADGI---------------------------------SGNPGKIGPPGKQGLPGI 1319
             G  G  G+                                 SG+ G +GP GK+G  G 
Sbjct: 985  PGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGE 1044

Query: 1320 RGGPGRTGLAGAPGP---------------PGVKGSSGLPGSPGIQGPKGEQGLPGQPGI 1364
            RG PG TG  G PGP                G KG  G PG  G +G KG+ G PGQPGI
Sbjct: 1045 RGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGI 1104

Query: 1365 QGKRGH---RGAQGDQGPCGDPGLKGQPGEYGVQGLT------GFQGFPGPKGPEGDAGI 1415
            +G  GH    GA G QG  G PGL GQ G+ GV+G        G QG PGP G +G+ G 
Sbjct: 1105 RGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGD 1164

Query: 1416 VGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGA 1475
            VG  GP G  G RG  GP G E   G  G  G  G+ G  GE G +G  G PGPPG PG 
Sbjct: 1165 VGSMGPHGAPGPRGPQGPTGSE---GTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGI 1221

Query: 1476 PGPR 1479
            PGP+
Sbjct: 1222 PGPK 1225



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 55/256 (21%), Positives = 100/256 (39%), Gaps = 35/256 (13%)

Query: 26  IVLCVAGVVVHAQEQGIDILHQLGLGGKDVRHSSPATAVPSASTPLPQGVHLTESGVIFK 85
           ++L    ++   Q   +D+L  LG+ G           VP      PQ     +      
Sbjct: 16  LLLAALQLLPGTQADPVDVLKALGVQGGQA-------GVPEGPGFCPQRTPEGDRAFRIG 68

Query: 86  NDAYIETPFVKILPV-NLGQPFTILTGLQSHRVNNAFLFSIRN-KNRLQLGVQLLPKKLV 143
             + +  P  ++ P  +  + F++L  L+    N + L SI + +   QLG+ L P    
Sbjct: 69  QASTLGIPTWELFPEGHFPENFSLLITLRGQPANQSVLLSIYDERGARQLGLALGP---A 125

Query: 144 VHIRGK--QPAVFNYSVHDEQWHSFAITIRNQSVSMFVECGKKYFSTETIPEV-----QT 196
           + + G   +P     ++ D +WH  A++I  + V++  +C       E  P V     + 
Sbjct: 126 LGLLGDPFRPLPQQVNLTDGRWHRVAVSIDGEMVTLVADC-------EAQPPVLGHGPRF 178

Query: 197 FDSNSVFTLGSMNNNSIHFEGIVCQLDIIPSAEASADYCRYVKQQCRQADKYQPETSIPC 256
                +  LG+ +     FEG + +L I P  +A+   C      C        +   P 
Sbjct: 179 ISIAGLTVLGTQDLGEKTFEGDIQELLISPDPQAAFQACERYLPDC--------DNLAPA 230

Query: 257 TTLIPTKIPEHSPPPK 272
            T+ P   PE +P P+
Sbjct: 231 ATVAPQGEPE-TPRPR 245


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score =  895 bits (2314), Expect = 0.0
 Identities = 536/1289 (41%), Positives = 657/1289 (50%), Gaps = 123/1289 (9%)

Query: 487  LRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQP 546
            L+G  GD GP GP GP G+ GP GK G RG  G  G  G+PG PG KG +G  G  PG P
Sbjct: 423  LKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGL-PGLP 481

Query: 547  -VPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLA 605
               G +GD G  GL GPPG  G++G  G  G  GLPGE G  G  G  G PG PG  G+ 
Sbjct: 482  GEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVR 541

Query: 606  GPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLD 665
            G +G  GPKG+ G  G PG  GQ G  G +G+PG          QG  G  G++GP G  
Sbjct: 542  GMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG---------PQGAIGPHGEKGPQGKP 592

Query: 666  GSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGEL 725
            G PG+ G  GPPG PG  G  G  G  GP+G  GP+G  G +G+ G+ G +G +G  GE 
Sbjct: 593  GLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEK 652

Query: 726  GEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPE 785
            GE G+PG KG +         G  G  G+ G PG +G  GP GP+G  G  G PG  G  
Sbjct: 653  GEDGFPGFKGDI---------GVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLM 703

Query: 786  GPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQ 845
            G KG LG    PG PG  G QG +G +G  G  G  G+ G +G +G+ GP G +G  G +
Sbjct: 704  GEKGKLG---VPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPR 760

Query: 846  GNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPL 905
            G  G  G TG  G  G  G  G  G  GERG PGP GP G      +PGP G PGP G  
Sbjct: 761  GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNG------FPGPKGPPGPPGKD 814

Query: 906  GLPGHVGARG---------PPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPH 956
            GLPGH G RG         PPG  G  G +G+ G  G +GE+G  G  G  G+QG  G  
Sbjct: 815  GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTA 874

Query: 957  GLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGE---PGLRGLQGDVGPPGEMGMEGPP 1013
            G  G  G+PG  G  GK G  GL G  G+RGLPG    PGL+G +G  GPPG  G  G  
Sbjct: 875  GKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGER 934

Query: 1014 GTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLP 1073
            G  G  G  G PG  G  G  G+ G  G PG +G  G  G +G+QG  GL G  G  G+ 
Sbjct: 935  GAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA 994

Query: 1074 GEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSR 1133
            GEDG+KGE+G PG  G  G  G+ G PGP G +G  GQ G  G  G+ G  GP G  G++
Sbjct: 995  GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK 1054

Query: 1134 G---------PPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLP 1184
            G         PPG IG  G  G  G +G  G +G MGP G PG  G  G  G  GP G P
Sbjct: 1055 GDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPP 1114

Query: 1185 G------PKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGA 1238
            G      P GEKG PGE     G PG +GEPG  G +GERGE G  G  G  G PG +G 
Sbjct: 1115 GGVGNLGPPGEKGEPGES----GSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGP 1170

Query: 1239 TGQQ---------------GPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGL 1283
            TG                 GPPGE G +G+ G KG+RG +G  G+ G+PGP+G+ G PG 
Sbjct: 1171 TGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP 1230

Query: 1284 QGLLGP---KGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGS 1340
             G  GP    G +G  G  G  G+PG IG PGK G  G  G  G+ G  G  G PG  G 
Sbjct: 1231 LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQ 1290

Query: 1341 SGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGF 1400
             G PG+ G  GP G  G PG PG+   RG  GA+G++G  G  GL G PGE   QG  G 
Sbjct: 1291 QGRPGATGQAGPPGPVGPPGLPGL---RGDAGAKGEKGHPGLIGLIGPPGE---QGEKGD 1344

Query: 1401 QGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGP 1460
            +G PGP+G  G  G +GI G  GPIG              GP G  GP G KG +G TGP
Sbjct: 1345 RGLPGPQGSPGQKGEMGIPGASGPIGPG------------GPPGLPGPAGPKGAKGATGP 1392

Query: 1461 QGPRGQPGPPGPPGAPGPRKQMDINAAIQALIESNTALQMESYQNTEVTLIDHS------ 1514
             GP+G+ G  GPPG PGP  ++     IQ   ++  ++        +  +          
Sbjct: 1393 GGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1452

Query: 1515 --EEIFKTLNYLSNLLHSIKNPLGTRDNPARICKDLLNCEQKVSDGKYWIDPNLGCPSDA 1572
              EEIF +L+ L   +  ++ P GT+D+PAR C+DL  C  ++ DG+YW+DPN GC  DA
Sbjct: 1453 GLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDA 1512

Query: 1573 IEVFCNFSAGGQTCLPP-VSVTKLEF------GVGKVQMNFLHLLSSEATHIITIHCLNT 1625
              VFCNF+AGG+TC+ P   VT+  +       VG VQ+ FL LLS  A   ++  C   
Sbjct: 1513 FRVFCNFTAGGETCVTPRDDVTQFSYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPCSGA 1572

Query: 1626 PRWTSTQTSGPGLPIGFKGWNGQIFKVNTLLEPKVLSDDCKIQDGSWHKATFLFHTQEPN 1685
             R           P+  +G N       T    K   D C+ Q G   +      T    
Sbjct: 1573 AR---------DGPLRLRGANEDELSPETSPYVKEFRDGCQTQQG---RTVLEVRTPVLE 1620

Query: 1686 QLPVIEVQKLPHLKTERKYYIDSSSVCFL 1714
            QLPV++          R+  +    VCF+
Sbjct: 1621 QLPVLDASFSDLGAPPRRGGVLLGPVCFM 1649



 Score =  551 bits (1419), Expect = e-156
 Identities = 349/852 (40%), Positives = 414/852 (48%), Gaps = 133/852 (15%)

Query: 754  QTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPP----------GPPGLK 803
            Q  +P  Q P+     E     +  P +    GP+GL G +G P          GPPG +
Sbjct: 259  QNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPE 318

Query: 804  GTQGEEGPIGAFGELGPRGKPGQK---GYAGEPGPEGLKGEVGDQ-------GNIGKIGE 853
            G  G  GP G  G  GP G PG++   G AG PG +G  G  G         G+ G  G+
Sbjct: 319  GPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--GD 376

Query: 854  TGPV--------------------GLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYP 893
             GPV                    G PG +G TG  G  G+ GSPG  G  G+ G  G  
Sbjct: 377  KGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPR 436

Query: 894  GPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKR 953
            GP G+ GP G  G  G  GA G  G  G  G +G RG DGL G  G +G +G+ G QG  
Sbjct: 437  GPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLP 496

Query: 954  GPHGLIGKTGNPGE---RGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGME 1010
            GP G  G+ G+ GE   RG  G+ G +GL G  G  G+PG PG+RG+ G  GP G +G +
Sbjct: 497  GPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQ 556

Query: 1011 ---GPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKD------ 1061
               GPPG +G  G QG PG +G +G  G  G  G+PGL G PG+ G  G  GK+      
Sbjct: 557  GEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTK 616

Query: 1062 ------------------GLKGVPGGRGLPGEDGEKGEMGLPGI---------------- 1087
                              G+KGV G RGL G  GEKGE G PG                 
Sbjct: 617  GNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVP 676

Query: 1088 --------IGPLGRSGQTGLPGPEGI------VGIPGQRGRPGKKGDKGQI------GPT 1127
                     GP GR+G TG PGP G+      +G+PG  G PG++G KG +      G +
Sbjct: 677  GSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGAS 736

Query: 1128 GEVGSR------GPPGKIGKSGPKGARGTRGAVGHLGLMGP---DGEPGIPGYRGHQGQP 1178
            GE G+R      GP G+ G +GP+G RG RGA G  G  G    DG  G PG RG  G  
Sbjct: 737  GEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQ 796

Query: 1179 GPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGA 1238
            GP+G PGPKG  G PG+D    G PG  G+ G VG QG+ G PG  G  G  G  G  G 
Sbjct: 797  GPNGFPGPKGPPGPPGKD----GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGP 852

Query: 1239 TGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGA 1298
             G++G PG PG  GEQGL G  G EG KG  G PG  GK G  GL+G  G +G+ G  G 
Sbjct: 853  MGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGG 912

Query: 1299 DGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAP------GPPGVKGSSGLPGSPGIQGP 1352
             G+ GN G  GPPG  G PG RG  G  G  G P      GPPG  G  G+PG  G  GP
Sbjct: 913  PGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP 972

Query: 1353 KGEQGLPGQ---PGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGP 1409
             G  G+ G    PG  G  G  G  GD+G  GDPG KG  G  G  G  G  G  GP G 
Sbjct: 973  TGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQ 1032

Query: 1410 EGDAGIVGISGPKGPIGH---RGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQ 1466
             G AG  G  G +GP GH   +G+ G  G  G  GP G  G  G  G +GETG  GP G 
Sbjct: 1033 PGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGP 1092

Query: 1467 PGPPGPPGAPGP 1478
            PGPPGP G  GP
Sbjct: 1093 PGPPGPRGPAGP 1104



 Score =  289 bits (740), Expect = 1e-77
 Identities = 172/368 (46%), Positives = 193/368 (52%), Gaps = 33/368 (8%)

Query: 484  MEYLRGPKGDTGPPGPPGPAGIPGPSGKR---GPRGIPGPHGNPGLPGLPGPKGPKGDPG 540
            ++ L GP G+ G  G  GP G PGP G R   GP G  GP G PG  G  GP G KG+PG
Sbjct: 1071 LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1130

Query: 541  FSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPG 600
             S      G  G QG  G+ GP G +G+KG  G PG PG PG +G  G  G  G+PG  G
Sbjct: 1131 ES------GSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG 1184

Query: 601  RQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRG 660
              G  GP G  GP+G  G  G  GE G+         PG  G  G  G  G PG  G RG
Sbjct: 1185 FPGDPGPPGEGGPRGQDGAKGDRGEDGE---------PGQPGSPGPTGENGPPGPLGKRG 1235

Query: 661  PAGLDGSPGLVGGTGPPGFP---GLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKG 717
            PAG  GS G  GG G  G P   G  G  GPVGP GPAG PGP GL   +GLPG  G +G
Sbjct: 1236 PAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL---RGLPGSVGQQG 1292

Query: 718  EQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIG 777
              G  G+ G P      G VG PG PG+RG +G  G+ G PGL G  GPPG +G  GD G
Sbjct: 1293 RPGATGQAGPP------GPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRG 1346

Query: 778  IPGQNGPEGPK---GLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPG 834
            +PG  G  G K   G+ G  GP GP G  G  G  GP GA G  GP G  G+KG  G PG
Sbjct: 1347 LPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPG 1406

Query: 835  PEGLKGEV 842
              G  GEV
Sbjct: 1407 HPGPPGEV 1414



 Score =  241 bits (614), Expect = 6e-63
 Identities = 143/344 (41%), Positives = 176/344 (51%), Gaps = 43/344 (12%)

Query: 1179 GPSGLPGPKGE----------KGYPGED--STVLGPPGPRGEPGPVGDQGERGEPGAEGY 1226
            GP GL G KGE          +G PG +  + ++GPPG +G PGPVGD GERG PG  G 
Sbjct: 291  GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 350

Query: 1227 KGHVGVPGLRGAT-----------GQQGPPGEPGDQGEQGLKGE-----RGSEGNKGKKG 1270
             G  G PG  G +           G +GP     +   Q +  +     RG  G  G  G
Sbjct: 351  PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTG 410

Query: 1271 APGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLA- 1329
             PGP G+PG PGL+G  G  G QG  G  G++G PGK G  G+ G  G RG PG  G+  
Sbjct: 411  RPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKG 470

Query: 1330 -----GAPGPPGVK------GSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQG 1378
                 G PG PG K      G+ GLPG PG  G +G+ G  G  G+ G+ G RG  G +G
Sbjct: 471  DRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKG 530

Query: 1379 P---CGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLG 1435
            P    G PG++G  G  G +G  G QG PGP G +G  G  G+ GP+G IG  G  GP G
Sbjct: 531  PPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQG 590

Query: 1436 REGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPR 1479
            + G+ G  G  GP G  G  G  G +G +G  GP GP G PGPR
Sbjct: 591  KPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR 634



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 43/178 (24%), Positives = 85/178 (47%), Gaps = 12/178 (6%)

Query: 88  AYIETPFVKILPVNLGQPFTILTGLQSHRVNNAFLFSIRNKNRL-QLGVQL-LPKKLVVH 145
           A +  P  ++ P    + F++LT +++     A L ++ +   + QLG++L  P + +  
Sbjct: 66  AQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPVRFLYE 125

Query: 146 IRG------KQPAVFNYSVHDEQWHSFAITIRNQSVSMFVECGKKYFSTETIPEV--QTF 197
            +        QP     S+ D +WH  A+ ++ QSV++ V+C K+   T  +P       
Sbjct: 126 DQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRV--TRPLPRSARPVL 183

Query: 198 DSNSVFTLGSMNNNSIHFEGIVCQLDIIPSAEASADYCRYVKQQCRQADKYQPETSIP 255
           D++ V   G+   +   FEG V +L I+P  +A+ + C   + +C    + +P+   P
Sbjct: 184 DTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQP 241


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score =  895 bits (2314), Expect = 0.0
 Identities = 536/1289 (41%), Positives = 657/1289 (50%), Gaps = 123/1289 (9%)

Query: 487  LRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQP 546
            L+G  GD GP GP GP G+ GP GK G RG  G  G  G+PG PG KG +G  G  PG P
Sbjct: 402  LKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGL-PGLP 460

Query: 547  -VPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLA 605
               G +GD G  GL GPPG  G++G  G  G  GLPGE G  G  G  G PG PG  G+ 
Sbjct: 461  GEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVR 520

Query: 606  GPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLD 665
            G +G  GPKG+ G  G PG  GQ G  G +G+PG          QG  G  G++GP G  
Sbjct: 521  GMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG---------PQGAIGPHGEKGPQGKP 571

Query: 666  GSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGEL 725
            G PG+ G  GPPG PG  G  G  G  GP+G  GP+G  G +G+ G+ G +G +G  GE 
Sbjct: 572  GLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEK 631

Query: 726  GEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPE 785
            GE G+PG KG +         G  G  G+ G PG +G  GP GP+G  G  G PG  G  
Sbjct: 632  GEDGFPGFKGDI---------GVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLM 682

Query: 786  GPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQ 845
            G KG LG    PG PG  G QG +G +G  G  G  G+ G +G +G+ GP G +G  G +
Sbjct: 683  GEKGKLG---VPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPR 739

Query: 846  GNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPL 905
            G  G  G TG  G  G  G  G  G  GERG PGP GP G      +PGP G PGP G  
Sbjct: 740  GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNG------FPGPKGPPGPPGKD 793

Query: 906  GLPGHVGARG---------PPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPH 956
            GLPGH G RG         PPG  G  G +G+ G  G +GE+G  G  G  G+QG  G  
Sbjct: 794  GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTA 853

Query: 957  GLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGE---PGLRGLQGDVGPPGEMGMEGPP 1013
            G  G  G+PG  G  GK G  GL G  G+RGLPG    PGL+G +G  GPPG  G  G  
Sbjct: 854  GKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGER 913

Query: 1014 GTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLP 1073
            G  G  G  G PG  G  G  G+ G  G PG +G  G  G +G+QG  GL G  G  G+ 
Sbjct: 914  GAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA 973

Query: 1074 GEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSR 1133
            GEDG+KGE+G PG  G  G  G+ G PGP G +G  GQ G  G  G+ G  GP G  G++
Sbjct: 974  GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK 1033

Query: 1134 ---------GPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLP 1184
                     GPPG IG  G  G  G +G  G +G MGP G PG  G  G  G  GP G P
Sbjct: 1034 GDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPP 1093

Query: 1185 ------GPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGA 1238
                  GP GEKG PGE     G PG +GEPG  G +GERGE G  G  G  G PG +G 
Sbjct: 1094 GGVGNLGPPGEKGEPGES----GSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGP 1149

Query: 1239 TGQQ---------------GPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGL 1283
            TG                 GPPGE G +G+ G KG+RG +G  G+ G+PGP+G+ G PG 
Sbjct: 1150 TGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP 1209

Query: 1284 QGLLGP---KGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGS 1340
             G  GP    G +G  G  G  G+PG IG PGK G  G  G  G+ G  G  G PG  G 
Sbjct: 1210 LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQ 1269

Query: 1341 SGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGF 1400
             G PG+ G  GP G  G PG PG+   RG  GA+G++G  G  GL G PGE   QG  G 
Sbjct: 1270 QGRPGATGQAGPPGPVGPPGLPGL---RGDAGAKGEKGHPGLIGLIGPPGE---QGEKGD 1323

Query: 1401 QGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGP 1460
            +G PGP+G  G  G +GI G  GPIG              GP G  GP G KG +G TGP
Sbjct: 1324 RGLPGPQGSPGQKGEMGIPGASGPIGPG------------GPPGLPGPAGPKGAKGATGP 1371

Query: 1461 QGPRGQPGPPGPPGAPGPRKQMDINAAIQALIESNTALQMESYQNTEVTLIDHS------ 1514
             GP+G+ G  GPPG PGP  ++     IQ   ++  ++        +  +          
Sbjct: 1372 GGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1431

Query: 1515 --EEIFKTLNYLSNLLHSIKNPLGTRDNPARICKDLLNCEQKVSDGKYWIDPNLGCPSDA 1572
              EEIF +L+ L   +  ++ P GT+D+PAR C+DL  C  ++ DG+YW+DPN GC  DA
Sbjct: 1432 GLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDA 1491

Query: 1573 IEVFCNFSAGGQTCLPP-VSVTKLEF------GVGKVQMNFLHLLSSEATHIITIHCLNT 1625
              VFCNF+AGG+TC+ P   VT+  +       VG VQ+ FL LLS  A   ++  C   
Sbjct: 1492 FRVFCNFTAGGETCVTPRDDVTQFSYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPCSGA 1551

Query: 1626 PRWTSTQTSGPGLPIGFKGWNGQIFKVNTLLEPKVLSDDCKIQDGSWHKATFLFHTQEPN 1685
             R           P+  +G N       T    K   D C+ Q G   +      T    
Sbjct: 1552 AR---------DGPLRLRGANEDELSPETSPYVKEFRDGCQTQQG---RTVLEVRTPVLE 1599

Query: 1686 QLPVIEVQKLPHLKTERKYYIDSSSVCFL 1714
            QLPV++          R+  +    VCF+
Sbjct: 1600 QLPVLDASFSDLGAPPRRGGVLLGPVCFM 1628



 Score =  548 bits (1412), Expect = e-155
 Identities = 344/827 (41%), Positives = 405/827 (48%), Gaps = 133/827 (16%)

Query: 779  PGQNGPEGPKGLLGNRGPP----------GPPGLKGTQGEEGPIGAFGELGPRGKPGQK- 827
            P      GP+GL G +G P          GPPG +G  G  GP G  G  GP G PG++ 
Sbjct: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 322

Query: 828  --GYAGEPGPEGLKGEVGDQ-------GNIGKIGETGPV--------------------G 858
              G AG PG +G  G  G         G+ G  G+ GPV                    G
Sbjct: 323  PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG--GDKGPVVAAQEAQAQAILQQARLALRG 380

Query: 859  LPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPG 918
             PG +G TG  G  G+ GSPG  G  G+ G  G  GP G+ GP G  G  G  GA G  G
Sbjct: 381  PPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARG 440

Query: 919  SQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGE---RGFQGKPG 975
              G  G +G RG DGL G  G +G +G+ G QG  GP G  G+ G+ GE   RG  G+ G
Sbjct: 441  MPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESG 500

Query: 976  LQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGME---GPPGTEGESGLQGEPGAKGDVG 1032
             +GL G  G  G+PG PG+RG+ G  GP G +G +   GPPG +G  G QG PG +G +G
Sbjct: 501  PRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIG 560

Query: 1033 TAGSVGGTGEPGLRGEPGAPGEEGLQGKD------------------------GLKGVPG 1068
              G  G  G+PGL G PG+ G  G  GK+                        G+KGV G
Sbjct: 561  PHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDG 620

Query: 1069 GRGLPGEDGEKGEMGLPGI------------------------IGPLGRSGQTGLPGPEG 1104
             RGL G  GEKGE G PG                          GP GR+G TG PGP G
Sbjct: 621  IRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPG 680

Query: 1105 I------VGIPGQRGRPGKKGDKGQI------GPTGEVGSR------GPPGKIGKSGPKG 1146
            +      +G+PG  G PG++G KG +      G +GE G+R      GP G+ G +GP+G
Sbjct: 681  LMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRG 740

Query: 1147 ARGTRGAVGHLGLMGP---DGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPP 1203
             RG RGA G  G  G    DG  G PG RG  G  GP+G PGPKG  G PG+D    G P
Sbjct: 741  QRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKD----GLP 796

Query: 1204 GPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSE 1263
            G  G+ G VG QG+ G PG  G  G  G  G  G  G++G PG PG  GEQGL G  G E
Sbjct: 797  GHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKE 856

Query: 1264 GNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGP 1323
            G KG  G PG  GK G  GL+G  G +G+ G  G  G+ GN G  GPPG  G PG RG  
Sbjct: 857  GTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAA 916

Query: 1324 GRTGLAGAP------GPPGVKGSSGLPGSPGIQGPKGEQGLPGQ---PGIQGKRGHRGAQ 1374
            G  G  G P      GPPG  G  G+PG  G  GP G  G+ G    PG  G  G  G  
Sbjct: 917  GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGED 976

Query: 1375 GDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGH---RGNT 1431
            GD+G  GDPG KG  G  G  G  G  G  GP G  G AG  G  G +GP GH   +G+ 
Sbjct: 977  GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1036

Query: 1432 GPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGP 1478
            G  G  G  GP G  G  G  G +GETG  GP G PGPPGP G  GP
Sbjct: 1037 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGP 1083



 Score =  421 bits (1082), Expect = e-117
 Identities = 264/641 (41%), Positives = 310/641 (48%), Gaps = 98/641 (15%)

Query: 912  GARGPPGSQGP-KGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNP----- 965
            G R  P +Q P + QR  +     L     Q    E   Q   GP GL G+ G P     
Sbjct: 231  GQRERPQNQQPHRAQRSPQQQPSRLHRPQNQ----EPQSQAAHGPRGLKGEKGEPAVLEP 286

Query: 966  -----GERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTE---- 1016
                 G  G +G  GL G PG  G+ G  G+PG RG  G  G PG  G  GPPGT     
Sbjct: 287  GMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLP 346

Query: 1017 -------GESG--------------------LQGEPGAKGDVGTAGSVGGTGEPGLRGEP 1049
                   G+ G                    L+G PG  G  G  G +G  G PGL+GE 
Sbjct: 347  FRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGES 406

Query: 1050 GAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIP 1109
            G  G +G +G  GL G PG  G  G  G  G  G+PG  G  G  G  GLP      G+P
Sbjct: 407  GDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLP------GLP 460

Query: 1110 GQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIP 1169
            G++G  G  G +G  GP GE G RG  G+I   GP+G  G  G  G LG  GP G PG P
Sbjct: 461  GEKGHRGDTGAQGLPGPPGEDGERGDDGEI---GPRGLPGESGPRGLLGPKGPPGIPGPP 517

Query: 1170 GYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGH 1229
            G RG  G  GP G  GP+GE G PG+     G PG +G PGP G  G  GE      KG 
Sbjct: 518  GVRGMDGPQGPKGSLGPQGEPGPPGQQ----GTPGTQGLPGPQGAIGPHGE------KGP 567

Query: 1230 VGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGP 1289
             G PGL G  G  GPPG PG +G  G KG +G  G +G  G PGP G  G+ G++GL G 
Sbjct: 568  QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH 627

Query: 1290 K------GIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSS-- 1341
            K      G  G+ G  G+ G+ G++G PG +G  G  G  GRTG  G PGPPG+ G    
Sbjct: 628  KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 687

Query: 1342 ----GLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGD---PGLKGQPGEYGV 1394
                GLPG PG QGPKG  G PG PG  G++G RG  G  GP G+    G +GQ G  G 
Sbjct: 688  LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 747

Query: 1395 QGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGF 1454
             G +G +G  G  GP G  G  G+ GP+GP G  G  GP G  G  G  G  G RGE GF
Sbjct: 748  TGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGF 807

Query: 1455 RGETGPQGP------------------RGQPGPPGPPGAPG 1477
            +G+TGP GP                  RG PGPPGPPG  G
Sbjct: 808  QGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQG 848



 Score =  289 bits (740), Expect = 1e-77
 Identities = 172/368 (46%), Positives = 193/368 (52%), Gaps = 33/368 (8%)

Query: 484  MEYLRGPKGDTGPPGPPGPAGIPGPSGKR---GPRGIPGPHGNPGLPGLPGPKGPKGDPG 540
            ++ L GP G+ G  G  GP G PGP G R   GP G  GP G PG  G  GP G KG+PG
Sbjct: 1050 LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1109

Query: 541  FSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPG 600
             S      G  G QG  G+ GP G +G+KG  G PG PG PG +G  G  G  G+PG  G
Sbjct: 1110 ES------GSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG 1163

Query: 601  RQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRG 660
              G  GP G  GP+G  G  G  GE G+         PG  G  G  G  G PG  G RG
Sbjct: 1164 FPGDPGPPGEGGPRGQDGAKGDRGEDGE---------PGQPGSPGPTGENGPPGPLGKRG 1214

Query: 661  PAGLDGSPGLVGGTGPPGFP---GLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKG 717
            PAG  GS G  GG G  G P   G  G  GPVGP GPAG PGP GL   +GLPG  G +G
Sbjct: 1215 PAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL---RGLPGSVGQQG 1271

Query: 718  EQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIG 777
              G  G+ G P      G VG PG PG+RG +G  G+ G PGL G  GPPG +G  GD G
Sbjct: 1272 RPGATGQAGPP------GPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRG 1325

Query: 778  IPGQNGPEGPK---GLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPG 834
            +PG  G  G K   G+ G  GP GP G  G  G  GP GA G  GP G  G+KG  G PG
Sbjct: 1326 LPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPG 1385

Query: 835  PEGLKGEV 842
              G  GEV
Sbjct: 1386 HPGPPGEV 1393



 Score =  241 bits (616), Expect = 3e-63
 Identities = 144/348 (41%), Positives = 177/348 (50%), Gaps = 43/348 (12%)

Query: 1175 QGQPGPSGLPGPKGE----------KGYPGED--STVLGPPGPRGEPGPVGDQGERGEPG 1222
            Q   GP GL G KGE          +G PG +  + ++GPPG +G PGPVGD GERG PG
Sbjct: 266  QAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPG 325

Query: 1223 AEGYKGHVGVPGLRGAT-----------GQQGPPGEPGDQGEQGLKGE-----RGSEGNK 1266
              G  G  G PG  G +           G +GP     +   Q +  +     RG  G  
Sbjct: 326  RAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPM 385

Query: 1267 GKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRT 1326
            G  G PGP G+PG PGL+G  G  G QG  G  G++G PGK G  G+ G  G RG PG  
Sbjct: 386  GYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDP 445

Query: 1327 GLA------GAPGPPGVK------GSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQ 1374
            G+       G PG PG K      G+ GLPG PG  G +G+ G  G  G+ G+ G RG  
Sbjct: 446  GVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLL 505

Query: 1375 GDQGP---CGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNT 1431
            G +GP    G PG++G  G  G +G  G QG PGP G +G  G  G+ GP+G IG  G  
Sbjct: 506  GPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEK 565

Query: 1432 GPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPR 1479
            GP G+ G+ G  G  GP G  G  G  G +G +G  GP GP G PGPR
Sbjct: 566  GPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR 613



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 43/178 (24%), Positives = 85/178 (47%), Gaps = 12/178 (6%)

Query: 88  AYIETPFVKILPVNLGQPFTILTGLQSHRVNNAFLFSIRNKNRL-QLGVQL-LPKKLVVH 145
           A +  P  ++ P    + F++LT +++     A L ++ +   + QLG++L  P + +  
Sbjct: 66  AQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPVRFLYE 125

Query: 146 IRG------KQPAVFNYSVHDEQWHSFAITIRNQSVSMFVECGKKYFSTETIPEV--QTF 197
            +        QP     S+ D +WH  A+ ++ QSV++ V+C K+   T  +P       
Sbjct: 126 DQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRV--TRPLPRSARPVL 183

Query: 198 DSNSVFTLGSMNNNSIHFEGIVCQLDIIPSAEASADYCRYVKQQCRQADKYQPETSIP 255
           D++ V   G+   +   FEG V +L I+P  +A+ + C   + +C    + +P+   P
Sbjct: 184 DTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQP 241


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score =  895 bits (2314), Expect = 0.0
 Identities = 536/1289 (41%), Positives = 657/1289 (50%), Gaps = 123/1289 (9%)

Query: 487  LRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQP 546
            L+G  GD GP GP GP G+ GP GK G RG  G  G  G+PG PG KG +G  G  PG P
Sbjct: 509  LKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGL-PGLP 567

Query: 547  -VPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLA 605
               G +GD G  GL GPPG  G++G  G  G  GLPGE G  G  G  G PG PG  G+ 
Sbjct: 568  GEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVR 627

Query: 606  GPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLD 665
            G +G  GPKG+ G  G PG  GQ G  G +G+PG          QG  G  G++GP G  
Sbjct: 628  GMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG---------PQGAIGPHGEKGPQGKP 678

Query: 666  GSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGEL 725
            G PG+ G  GPPG PG  G  G  G  GP+G  GP+G  G +G+ G+ G +G +G  GE 
Sbjct: 679  GLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEK 738

Query: 726  GEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPE 785
            GE G+PG KG +         G  G  G+ G PG +G  GP GP+G  G  G PG  G  
Sbjct: 739  GEDGFPGFKGDI---------GVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLM 789

Query: 786  GPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQ 845
            G KG LG    PG PG  G QG +G +G  G  G  G+ G +G +G+ GP G +G  G +
Sbjct: 790  GEKGKLG---VPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPR 846

Query: 846  GNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPL 905
            G  G  G TG  G  G  G  G  G  GERG PGP GP G      +PGP G PGP G  
Sbjct: 847  GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNG------FPGPKGPPGPPGKD 900

Query: 906  GLPGHVGARG---------PPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPH 956
            GLPGH G RG         PPG  G  G +G+ G  G +GE+G  G  G  G+QG  G  
Sbjct: 901  GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTA 960

Query: 957  GLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGE---PGLRGLQGDVGPPGEMGMEGPP 1013
            G  G  G+PG  G  GK G  GL G  G+RGLPG    PGL+G +G  GPPG  G  G  
Sbjct: 961  GKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGER 1020

Query: 1014 GTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLP 1073
            G  G  G  G PG  G  G  G+ G  G PG +G  G  G +G+QG  GL G  G  G+ 
Sbjct: 1021 GAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA 1080

Query: 1074 GEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSR 1133
            GEDG+KGE+G PG  G  G  G+ G PGP G +G  GQ G  G  G+ G  GP G  G++
Sbjct: 1081 GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK 1140

Query: 1134 ---------GPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLP 1184
                     GPPG IG  G  G  G +G  G +G MGP G PG  G  G  G  GP G P
Sbjct: 1141 GDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPP 1200

Query: 1185 ------GPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGA 1238
                  GP GEKG PGE     G PG +GEPG  G +GERGE G  G  G  G PG +G 
Sbjct: 1201 GGVGNLGPPGEKGEPGES----GSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGP 1256

Query: 1239 TGQQ---------------GPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGL 1283
            TG                 GPPGE G +G+ G KG+RG +G  G+ G+PGP+G+ G PG 
Sbjct: 1257 TGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP 1316

Query: 1284 QGLLGP---KGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGS 1340
             G  GP    G +G  G  G  G+PG IG PGK G  G  G  G+ G  G  G PG  G 
Sbjct: 1317 LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQ 1376

Query: 1341 SGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGF 1400
             G PG+ G  GP G  G PG PG+   RG  GA+G++G  G  GL G PGE   QG  G 
Sbjct: 1377 QGRPGATGQAGPPGPVGPPGLPGL---RGDAGAKGEKGHPGLIGLIGPPGE---QGEKGD 1430

Query: 1401 QGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGP 1460
            +G PGP+G  G  G +GI G  GPIG              GP G  GP G KG +G TGP
Sbjct: 1431 RGLPGPQGSPGQKGEMGIPGASGPIGPG------------GPPGLPGPAGPKGAKGATGP 1478

Query: 1461 QGPRGQPGPPGPPGAPGPRKQMDINAAIQALIESNTALQMESYQNTEVTLIDHS------ 1514
             GP+G+ G  GPPG PGP  ++     IQ   ++  ++        +  +          
Sbjct: 1479 GGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1538

Query: 1515 --EEIFKTLNYLSNLLHSIKNPLGTRDNPARICKDLLNCEQKVSDGKYWIDPNLGCPSDA 1572
              EEIF +L+ L   +  ++ P GT+D+PAR C+DL  C  ++ DG+YW+DPN GC  DA
Sbjct: 1539 GLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDA 1598

Query: 1573 IEVFCNFSAGGQTCLPP-VSVTKLEF------GVGKVQMNFLHLLSSEATHIITIHCLNT 1625
              VFCNF+AGG+TC+ P   VT+  +       VG VQ+ FL LLS  A   ++  C   
Sbjct: 1599 FRVFCNFTAGGETCVTPRDDVTQFSYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPCSGA 1658

Query: 1626 PRWTSTQTSGPGLPIGFKGWNGQIFKVNTLLEPKVLSDDCKIQDGSWHKATFLFHTQEPN 1685
             R           P+  +G N       T    K   D C+ Q G   +      T    
Sbjct: 1659 AR---------DGPLRLRGANEDELSPETSPYVKEFRDGCQTQQG---RTVLEVRTPVLE 1706

Query: 1686 QLPVIEVQKLPHLKTERKYYIDSSSVCFL 1714
            QLPV++          R+  +    VCF+
Sbjct: 1707 QLPVLDASFSDLGAPPRRGGVLLGPVCFM 1735



 Score =  289 bits (740), Expect = 1e-77
 Identities = 172/368 (46%), Positives = 193/368 (52%), Gaps = 33/368 (8%)

Query: 484  MEYLRGPKGDTGPPGPPGPAGIPGPSGKR---GPRGIPGPHGNPGLPGLPGPKGPKGDPG 540
            ++ L GP G+ G  G  GP G PGP G R   GP G  GP G PG  G  GP G KG+PG
Sbjct: 1157 LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1216

Query: 541  FSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPG 600
             S      G  G QG  G+ GP G +G+KG  G PG PG PG +G  G  G  G+PG  G
Sbjct: 1217 ES------GSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG 1270

Query: 601  RQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRG 660
              G  GP G  GP+G  G  G  GE G+         PG  G  G  G  G PG  G RG
Sbjct: 1271 FPGDPGPPGEGGPRGQDGAKGDRGEDGE---------PGQPGSPGPTGENGPPGPLGKRG 1321

Query: 661  PAGLDGSPGLVGGTGPPGFP---GLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKG 717
            PAG  GS G  GG G  G P   G  G  GPVGP GPAG PGP GL   +GLPG  G +G
Sbjct: 1322 PAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL---RGLPGSVGQQG 1378

Query: 718  EQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIG 777
              G  G+ G P      G VG PG PG+RG +G  G+ G PGL G  GPPG +G  GD G
Sbjct: 1379 RPGATGQAGPP------GPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRG 1432

Query: 778  IPGQNGPEGPK---GLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPG 834
            +PG  G  G K   G+ G  GP GP G  G  G  GP GA G  GP G  G+KG  G PG
Sbjct: 1433 LPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPG 1492

Query: 835  PEGLKGEV 842
              G  GEV
Sbjct: 1493 HPGPPGEV 1500



 Score =  243 bits (621), Expect = 9e-64
 Identities = 154/402 (38%), Positives = 193/402 (48%), Gaps = 45/402 (11%)

Query: 1123 QIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQP--GP 1180
            Q+ PT +       G+ G   P+G        G       +  P +     H G    GP
Sbjct: 319  QVPPTADRFQAEEYGEGGTDPPEGPYDYTYGYGDDYREETELGPALSAETAHSGAAAHGP 378

Query: 1181 SGLPGPKGE----------KGYPGED--STVLGPPGPRGEPGPVGDQGERGEPGAEGYKG 1228
             GL G KGE          +G PG +  + ++GPPG +G PGPVGD GERG PG  G  G
Sbjct: 379  RGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPG 438

Query: 1229 HVGVPGLRGAT-----------GQQGPPGEPGDQGEQGLKGE-----RGSEGNKGKKGAP 1272
              G PG  G +           G +GP     +   Q +  +     RG  G  G  G P
Sbjct: 439  SDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRP 498

Query: 1273 GPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLA--- 1329
            GP G+PG PGL+G  G  G QG  G  G++G PGK G  G+ G  G RG PG  G+    
Sbjct: 499  GPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDR 558

Query: 1330 ---GAPGPPGVK------GSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGP- 1379
               G PG PG K      G+ GLPG PG  G +G+ G  G  G+ G+ G RG  G +GP 
Sbjct: 559  GFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPP 618

Query: 1380 --CGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGRE 1437
               G PG++G  G  G +G  G QG PGP G +G  G  G+ GP+G IG  G  GP G+ 
Sbjct: 619  GIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKP 678

Query: 1438 GIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPR 1479
            G+ G  G  GP G  G  G  G +G +G  GP GP G PGPR
Sbjct: 679  GLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR 720



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 43/178 (24%), Positives = 85/178 (47%), Gaps = 12/178 (6%)

Query: 88  AYIETPFVKILPVNLGQPFTILTGLQSHRVNNAFLFSIRNKNRL-QLGVQL-LPKKLVVH 145
           A +  P  ++ P    + F++LT +++     A L ++ +   + QLG++L  P + +  
Sbjct: 66  AQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPVRFLYE 125

Query: 146 IRG------KQPAVFNYSVHDEQWHSFAITIRNQSVSMFVECGKKYFSTETIPEV--QTF 197
            +        QP     S+ D +WH  A+ ++ QSV++ V+C K+   T  +P       
Sbjct: 126 DQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRV--TRPLPRSARPVL 183

Query: 198 DSNSVFTLGSMNNNSIHFEGIVCQLDIIPSAEASADYCRYVKQQCRQADKYQPETSIP 255
           D++ V   G+   +   FEG V +L I+P  +A+ + C   + +C    + +P+   P
Sbjct: 184 DTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQP 241


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  883 bits (2282), Expect = 0.0
 Identities = 569/1407 (40%), Positives = 682/1407 (48%), Gaps = 205/1407 (14%)

Query: 489  GPKGDTGPPGPPGPAG-IPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPV 547
            G KG  G P    P   + GP G  GP GI GP      PGL GP GP GDPG    +  
Sbjct: 435  GEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP------PGLQGPTGPPGDPG---DRGP 485

Query: 548  PGEKGDQGLSGLMGPPGMQ----------GDKG--------------------LKGHPG- 576
            PG  G  G  GL GPPG            G KG                    L+G PG 
Sbjct: 486  PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGP 545

Query: 577  --LPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGE 634
              L G PG  G PG +G  G  G PG QG  G +G PGP G  G  G PG  G  G  GE
Sbjct: 546  MGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGE 605

Query: 635  RGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGP 694
               PG +G +GF G  G PGD G RG  G  G PG      PPG  G+RG  G +GP G 
Sbjct: 606  ---PGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG------PPGDDGMRGEDGEIGPRGL 656

Query: 695  AGIPGPMGLSGNKGLPGIKGD------------KGEQGTAGELGEPGYPGDKGAVGLPGP 742
             G  GP GL G +G PG  G             KG  G  GE G PG  G+ G  GLPGP
Sbjct: 657  PGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGP 716

Query: 743  ------PGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGP 796
                  PG +G  G  G  G PG  GP G PG EG  G+ G  G  GP+GP G  G RG 
Sbjct: 717  QGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGV 776

Query: 797  PGPP---GLKGTQGEEGP------IGAFGELGPRGKPGQKGYAGEPGPEGLKGE---VGD 844
             G     GLKG++GE+G        G  G  G RG+ GQ G  GE GPEG KG     GD
Sbjct: 777  KGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGD 836

Query: 845  QGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGP 904
             G  G+ GE G +G+PG  G  G  G KG  G PG  G  GEKG  G  G PG  G  GP
Sbjct: 837  PGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP 896

Query: 905  LGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGN 964
             G  G  GARGP G  GPKG  G  GP G  GE+G QG +G  G  G +GP G  GK G 
Sbjct: 897  TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL 956

Query: 965  P------GERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGE 1018
            P      GE GFQGK G  G  G  G +G  GE G  G +G  GPPG  G +G PG  G+
Sbjct: 957  PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 1016

Query: 1019 SGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGE--- 1075
             G +G+PG +G  G  G  G  G PG RG PGA G  GL+G +G +G PG  G PGE   
Sbjct: 1017 EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGS 1076

Query: 1076 ------------------DGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGK 1117
                               G  GE G PG  GP G +G+ G+ GP G+ G  G  G PG+
Sbjct: 1077 AGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGE 1136

Query: 1118 KGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEP----------- 1166
             GDKG+IG  G+ GS+G     G++GP G  G +G VG  G+ G DGEP           
Sbjct: 1137 DGDKGEIGEPGQKGSKGDK---GENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQ 1193

Query: 1167 -GIPGYRGHQGQPGP---SGLPGPKGEKGYPGEDSTV--LGPPGPRGEPGPVGDQGERGE 1220
             G  G RG  G PGP    GLPGP GEKG  G+   +   GPPGPRG  GP G  G +G 
Sbjct: 1194 KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGP 1253

Query: 1221 PGAEGYKGHVGVPGLRGATGQQGPPGEP---GDQGEQGLKGE------------RGSEGN 1265
            PG+ G  G VG  G  G  G  GPPGE    G +GE+G KGE            +G  G+
Sbjct: 1254 PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGD 1313

Query: 1266 KGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQ------GLPGI 1319
             G KG PGP G PG PG  G  GP G  G  G  G  G+PG+ GPPG        G PG 
Sbjct: 1314 DGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGK 1373

Query: 1320 RGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGP 1379
            RG PG  G  G  G  G KG +G  G PG  GP G QG  G+PG +G RG  G  G+QG 
Sbjct: 1374 RGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGL 1433

Query: 1380 CGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGN--------- 1430
             G  G  G PG  G  GL G +G PG KG +G  G++G+ GP G  G +G+         
Sbjct: 1434 PGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGS 1493

Query: 1431 ---------TGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQ 1481
                      GP G  G  GP G  GP+G KG +G TGP G +G  G PGPPG+PGP   
Sbjct: 1494 PGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP--P 1551

Query: 1482 MDINAAIQALIESNTALQMESYQ-NTEVTLIDHS---EEIFKTLNYLSNLLHSIKNPLGT 1537
             ++   +  L    T    E  Q + +  ++D+S   EEIF +LN L   +  +K P+GT
Sbjct: 1552 GEVIQPLPILSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGT 1611

Query: 1538 RDNPARICKDLLNCEQKVSDGKYWIDPNLGCPSDAIEVFCNFSAGGQTCLPPVSVTK--- 1594
            + NPAR CKDL        DG+YWIDPN GC  D+ +V+CNF++GG+TC+ P   ++   
Sbjct: 1612 QTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVR 1671

Query: 1595 -------------LEFGVGK--------------VQMNFLHLLSSEATHIITIHCLNTPR 1627
                          EF  GK              VQM FL LL++ A    T HC  +  
Sbjct: 1672 ISSWPKEKPGSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAA 1731

Query: 1628 WTSTQTSGPGLPIGFKGWNGQIFKVNTLLEPKVLSDDCKIQDGSWHKATFLFHTQEPNQL 1687
            W    +      + F G N +    +     K L D C  + G + K     +T + +Q+
Sbjct: 1732 WYDVSSGSYDKALRFLGSNDEEMSYDNNPFIKTLYDGCASRKG-YEKTVIEINTPKIDQV 1790

Query: 1688 PVIEVQKLPHLKTERKYYIDSSSVCFL 1714
            P+++V         +K+  +   VCFL
Sbjct: 1791 PIVDVMINDFGDQNQKFGFEVGPVCFL 1817



 Score =  752 bits (1941), Expect = 0.0
 Identities = 432/959 (45%), Positives = 522/959 (54%), Gaps = 87/959 (9%)

Query: 488  RGPKGDTGPPGPP------------GPAGIPGPSGKR---GPRGIPGPHGNPGLPGLPGP 532
            RG +G  GPPGPP            GP G+PG +G R   GPRG PG  G PG+ G+ GP
Sbjct: 627  RGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP 686

Query: 533  KGPKGDPGFSPGQPVP----GEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPG 588
             GPKG+ G   G+P P    G  G QGL G  GP G  G+KG +G PGL GLPG      
Sbjct: 687  PGPKGNMG-PQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD---- 741

Query: 589  FAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKG 648
                 G PG+PG++G +G +G  GP G QG IG PG  G  G +G R   G++G KG KG
Sbjct: 742  -----GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVR---GLKGSKGEKG 793

Query: 649  RQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKG 708
              GFPG  GD G  G  G  G +G  G  G  G +G  GP G  GP+G  G  G  G  G
Sbjct: 794  EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG 853

Query: 709  LPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPG 768
            LPG  G +G +G+ G  G PG  G+KGA G+ G PG RG+ GP+G  G  G +GP+G PG
Sbjct: 854  LPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG 913

Query: 769  PEGF---PGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPG 825
            P+G     G  G PG+ GP+GP+G +G  GP GPPG  G  G  G  G  GE G +GK G
Sbjct: 914  PKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 973

Query: 826  QKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGP---LG 882
              G  G  GP+G  GE G    IG+ G  GP G PGE G+ G+ G++G +G PGP    G
Sbjct: 974  PPGPGGVVGPQGPTGETGP---IGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISG 1030

Query: 883  PQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLL------G 936
              G  G+ G+PG  G+PG  G  GL G  G +GPPG  G  G+RGS G  G +      G
Sbjct: 1031 KDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG 1090

Query: 937  EQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRG 996
             QG  G  GEKG  G++GP G  G+ G  G  G  G  G  G PG  GD+G  GEPG +G
Sbjct: 1091 PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKG 1150

Query: 997  LQGDV---GPPGEMGMEGPPGTEGESGLQGEP---------GAKGDVGTAGSVGGTGEPG 1044
             +GD    GPPG  G++GP G  G +G  GEP         G KGD G  G  G  G  G
Sbjct: 1151 SKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIG 1210

Query: 1045 LRGEPGAPGEEGLQ---GKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPG 1101
            L+G PG PGE+G     G  G  G PG RG  G +G  G  G PG +G +G  G+ G PG
Sbjct: 1211 LQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG 1270

Query: 1102 PEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMG 1161
              G  G PG+ G  G KG++G+ G  G  G+ GPPG  G  G  G +G  G VG  G  G
Sbjct: 1271 EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG 1330

Query: 1162 PDGEP------GIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQ 1215
            P GEP      G+ G +G  G PG  G PGP GE G PG       PPG RG PG  G +
Sbjct: 1331 PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG-------PPGKRGPPGAAGAE 1383

Query: 1216 GERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLK---GERGSEGNKGKKGAP 1272
            G +GE GA+G  G  G PG  G  G QGP G+PG +G +G+    GE+G  G  G+ G P
Sbjct: 1384 GRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1443

Query: 1273 GPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAP 1332
            GP G PG+PGL+G  G KG +G+ G  G+ G PG+ G  G +GLPG +G PG  G  G P
Sbjct: 1444 GPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIP 1503

Query: 1333 GPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGE 1391
            GP G  G  G PG PG QGPKG          +G  G  G +GD G  G PG  G PGE
Sbjct: 1504 GPAGPLGPPGPPGLPGPQGPKGN---------KGSTGPAGQKGDSGLPGPPGSPGPPGE 1553



 Score =  404 bits (1039), Expect = e-112
 Identities = 243/530 (45%), Positives = 271/530 (51%), Gaps = 39/530 (7%)

Query: 487  LRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQP 546
            L+G +G  GPPGP G  G  G +G  GP G+P   G PG  G PGP G KG PG    Q 
Sbjct: 1055 LKGGEGPQGPPGPVGSPGERGSAGTAGPIGLP---GRPGPQGPPGPAGEKGAPGEKGPQG 1111

Query: 547  VPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQ---- 602
              G  G QG  GL GP G  G  G  G  G  G PG++G  G  G  G PG PG Q    
Sbjct: 1112 PAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG 1171

Query: 603  --GLAGPEGNPGPKGAQGFIGSPGEAGQL---GPEGERGIPGIRGKKGFKGRQGFPGDFG 657
              G+AG +G PGP+G QG  G  G+ G     GP G  G+ G+ G  G KG  G  G  G
Sbjct: 1172 APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMG 1231

Query: 658  DRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKG 717
              GP G  G  G  G  GP G P   GSVG VG +G  G PG  G  G  G  G+ G KG
Sbjct: 1232 PPGPPGPRGPQGPNGADGPQGPP---GSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKG 1288

Query: 718  EQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIG 777
            E+G  GE G PG  G  GA G PG  G +G  GP G  GDPG  G  GP G +G  GD G
Sbjct: 1289 ERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKG 1348

Query: 778  IPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEG 837
              G  G  GP G  G  GPPGPP      G+ GP GA G  G +G+ G KG AG  GP G
Sbjct: 1349 EDGDPGQPGPPGPSGEAGPPGPP------GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPG 1402

Query: 838  LKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPG 897
              G VG QG  GK G  G  G+PG VG  G  G  G+ G PGP+GP       G PG  G
Sbjct: 1403 KTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPP------GLPGLKG 1456

Query: 898  VPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHG 957
             PG  G  G PG +G  GPPG QG KG RG      L G QG  GAKG+ G  G  GP G
Sbjct: 1457 DPGSKGEKGHPGLIGLIGPPGEQGEKGDRG------LPGTQGSPGAKGDGGIPGPAGPLG 1510

Query: 958  LIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEM 1007
              G  G PG +G +G  G  G  G  GD GLPG P      G  GPPGE+
Sbjct: 1511 PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPP------GSPGPPGEV 1554



 Score =  318 bits (815), Expect = 3e-86
 Identities = 192/426 (45%), Positives = 219/426 (51%), Gaps = 36/426 (8%)

Query: 488  RGPKGDTGPPGPPG---PAGIPGPSG------KRGPRGIPGPHGNPGLPGLPGPKGPKGD 538
            +G KG+ GPPGPPG   P G PG +G       RG +G+ G  G+ G  G PGP GP G 
Sbjct: 1152 KGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGL 1211

Query: 539  PGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGY 598
             G  PG P  GEKG+ G  G MGPPG  G +G +G  G  G  G  G  G  G +G  G 
Sbjct: 1212 QGL-PGPP--GEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1268

Query: 599  PGRQGLAGPEGNPG---PKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGD 655
            PG  G  GP G  G   PKG +G  G  G  G  GP G +G PG  G KG  G  GFPGD
Sbjct: 1269 PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD 1328

Query: 656  FG---DRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGI 712
             G   + GPAG DG  G  G  G PG PG  G  G  GP GP G  GP G +G +G  G 
Sbjct: 1329 PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGE 1388

Query: 713  KGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPG---P 769
            KG KGE G  G  G+ G  G +G  G PGP G+RG  GP G+ G PG  G  GPPG   P
Sbjct: 1389 KGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGP 1448

Query: 770  EGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGY 829
             G PG  G PG  G +G  GL+G  GPPG  G KG +G  G  G+ G  G  G PG  G 
Sbjct: 1449 PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGP 1508

Query: 830  AGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGV 889
             G PGP GL G  G +GN                G TG  G+KG+ G PGP G  G  G 
Sbjct: 1509 LGPPGPPGLPGPQGPKGN---------------KGSTGPAGQKGDSGLPGPPGSPGPPGE 1553

Query: 890  MGYPGP 895
            +  P P
Sbjct: 1554 VIQPLP 1559



 Score =  278 bits (710), Expect = 4e-74
 Identities = 164/365 (44%), Positives = 189/365 (51%), Gaps = 27/365 (7%)

Query: 484  MEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPR---GIPGPHGNPGLPGLPGPKGPKGDPG 540
            ++ L GP G+ G  G  GP G PGP G RGP+   G  GP G PG  G  G  G KG+PG
Sbjct: 1211 LQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG 1270

Query: 541  FSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPG 600
             +      G  G  G +G+ GP G +G+KG  G PG  G PG +G PG  G  G+PG  G
Sbjct: 1271 EA------GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVG 1324

Query: 601  RQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRG 660
              G  GP G PGP G  G  G  GE G  G  G  G  G  G  G  G++G PG  G  G
Sbjct: 1325 FPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEG 1384

Query: 661  PAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQG 720
              G  G+ G  G  GPP      G  GPVGP GPAG PGP      +GL GI G  GEQG
Sbjct: 1385 RQGEKGAKGEAGAEGPP------GKTGPVGPQGPAGKPGP------EGLRGIPGPVGEQG 1432

Query: 721  TAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPG 780
              G  G+ G PG  G  GLPG   ++G  G  G+ G PGL G  GPPG +G  GD G+PG
Sbjct: 1433 LPGAAGQDGPPGPMGPPGLPG---LKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1489

Query: 781  QNGPEGPK---GLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEG 837
              G  G K   G+ G  GP GPPG  G  G +GP G  G  GP G+ G  G  G PG  G
Sbjct: 1490 TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1549

Query: 838  LKGEV 842
              GEV
Sbjct: 1550 PPGEV 1554



 Score =  135 bits (340), Expect = 3e-31
 Identities = 88/238 (36%), Positives = 110/238 (46%), Gaps = 38/238 (15%)

Query: 1272 PGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGK--IGPPGKQGLPGIRGGPGRTGLA 1329
            P     PG+P    +     I G HGA G  G  G+  +  PG      + G PG  G A
Sbjct: 409  PNEEFGPGVPAETDIT-ETSING-HGAYGEKGQKGEPAVVEPGML----VEGPPGPAGPA 462

Query: 1330 GAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQG----------KRGHRGAQGD--- 1376
            G  GPPG++G +G PG PG +GP G  GLPG  G+ G          + G  G++G    
Sbjct: 463  GIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTIS 522

Query: 1377 -----------------QGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGIS 1419
                             +GP G  GL G+PG  G  G +G +G  G  GP+G  G+ G  
Sbjct: 523  AQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP 582

Query: 1420 GPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPG 1477
            GP G  G RG  G  G  G+ G  G  G RG  G  G  G +G RG+ GP GPPG PG
Sbjct: 583  GPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 640



 Score =  131 bits (329), Expect = 6e-30
 Identities = 87/196 (44%), Positives = 100/196 (51%), Gaps = 29/196 (14%)

Query: 485  EYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPG 544
            E LRG  G  G  G PG AG  GP         PGP G PGLPGL      KGDPG    
Sbjct: 1419 EGLRGIPGPVGEQGLPGAAGQDGP---------PGPMGPPGLPGL------KGDPGSK-- 1461

Query: 545  QPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGL---PGLPGEQGIPGFAGNIGSPGYPGR 601
                GEKG  GL GL+GPPG QG+KG +G PG    PG  G+ GIPG AG +G PG PG 
Sbjct: 1462 ----GEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL 1517

Query: 602  QGLAGPEGN---PGPKGAQGFIGSPGEAGQLGPEGE--RGIPGIRGKKGFKGRQGFPGDF 656
             G  GP+GN    GP G +G  G PG  G  GP GE  + +P +  KK  +  +G   D 
Sbjct: 1518 PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADA 1577

Query: 657  GDRGPAGLDGSPGLVG 672
             D      DG   + G
Sbjct: 1578 DDNILDYSDGMEEIFG 1593



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 46/165 (27%), Positives = 79/165 (47%), Gaps = 11/165 (6%)

Query: 88  AYIETPFVKILPVN-LGQPFTILTGLQSHRVNNAFLFSIRNKNRLQ-LGVQL--LPKKLV 143
           A +  P  ++ P     + F+IL  ++  +   +FL SI N++ +Q +GV++   P  L 
Sbjct: 80  AQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYNEHGIQQIGVEVGRSPVFLF 139

Query: 144 VHIRGKQPAVFNY------SVHDEQWHSFAITIRNQSVSMFVECGKKYFSTETIPEVQTF 197
               GK PA  +Y      ++ D +WH  AI++  ++V+M V+C KK        E    
Sbjct: 140 EDHTGK-PAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIV 198

Query: 198 DSNSVFTLGSMNNNSIHFEGIVCQLDIIPSAEASADYCRYVKQQC 242
           D+N +   G+   +   FEG + Q  I    +A+ DYC +    C
Sbjct: 199 DTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYSPDC 243


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  883 bits (2282), Expect = 0.0
 Identities = 569/1407 (40%), Positives = 682/1407 (48%), Gaps = 205/1407 (14%)

Query: 489  GPKGDTGPPGPPGPAG-IPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPV 547
            G KG  G P    P   + GP G  GP GI GP      PGL GP GP GDPG    +  
Sbjct: 384  GEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP------PGLQGPTGPPGDPG---DRGP 434

Query: 548  PGEKGDQGLSGLMGPPGMQ----------GDKG--------------------LKGHPG- 576
            PG  G  G  GL GPPG            G KG                    L+G PG 
Sbjct: 435  PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGP 494

Query: 577  --LPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGE 634
              L G PG  G PG +G  G  G PG QG  G +G PGP G  G  G PG  G  G  GE
Sbjct: 495  MGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGE 554

Query: 635  RGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGP 694
               PG +G +GF G  G PGD G RG  G  G PG      PPG  G+RG  G +GP G 
Sbjct: 555  ---PGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG------PPGDDGMRGEDGEIGPRGL 605

Query: 695  AGIPGPMGLSGNKGLPGIKGD------------KGEQGTAGELGEPGYPGDKGAVGLPGP 742
             G  GP GL G +G PG  G             KG  G  GE G PG  G+ G  GLPGP
Sbjct: 606  PGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGP 665

Query: 743  ------PGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGP 796
                  PG +G  G  G  G PG  GP G PG EG  G+ G  G  GP+GP G  G RG 
Sbjct: 666  QGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGV 725

Query: 797  PGPP---GLKGTQGEEGP------IGAFGELGPRGKPGQKGYAGEPGPEGLKGE---VGD 844
             G     GLKG++GE+G        G  G  G RG+ GQ G  GE GPEG KG     GD
Sbjct: 726  KGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGD 785

Query: 845  QGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGP 904
             G  G+ GE G +G+PG  G  G  G KG  G PG  G  GEKG  G  G PG  G  GP
Sbjct: 786  PGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP 845

Query: 905  LGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGN 964
             G  G  GARGP G  GPKG  G  GP G  GE+G QG +G  G  G +GP G  GK G 
Sbjct: 846  TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL 905

Query: 965  P------GERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGE 1018
            P      GE GFQGK G  G  G  G +G  GE G  G +G  GPPG  G +G PG  G+
Sbjct: 906  PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 965

Query: 1019 SGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGE--- 1075
             G +G+PG +G  G  G  G  G PG RG PGA G  GL+G +G +G PG  G PGE   
Sbjct: 966  EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGS 1025

Query: 1076 ------------------DGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGK 1117
                               G  GE G PG  GP G +G+ G+ GP G+ G  G  G PG+
Sbjct: 1026 AGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGE 1085

Query: 1118 KGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEP----------- 1166
             GDKG+IG  G+ GS+G     G++GP G  G +G VG  G+ G DGEP           
Sbjct: 1086 DGDKGEIGEPGQKGSKGDK---GENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQ 1142

Query: 1167 -GIPGYRGHQGQPGP---SGLPGPKGEKGYPGEDSTV--LGPPGPRGEPGPVGDQGERGE 1220
             G  G RG  G PGP    GLPGP GEKG  G+   +   GPPGPRG  GP G  G +G 
Sbjct: 1143 KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGP 1202

Query: 1221 PGAEGYKGHVGVPGLRGATGQQGPPGEP---GDQGEQGLKGE------------RGSEGN 1265
            PG+ G  G VG  G  G  G  GPPGE    G +GE+G KGE            +G  G+
Sbjct: 1203 PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGD 1262

Query: 1266 KGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQ------GLPGI 1319
             G KG PGP G PG PG  G  GP G  G  G  G  G+PG+ GPPG        G PG 
Sbjct: 1263 DGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGK 1322

Query: 1320 RGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGP 1379
            RG PG  G  G  G  G KG +G  G PG  GP G QG  G+PG +G RG  G  G+QG 
Sbjct: 1323 RGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGL 1382

Query: 1380 CGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGN--------- 1430
             G  G  G PG  G  GL G +G PG KG +G  G++G+ GP G  G +G+         
Sbjct: 1383 PGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGS 1442

Query: 1431 ---------TGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQ 1481
                      GP G  G  GP G  GP+G KG +G TGP G +G  G PGPPG+PGP   
Sbjct: 1443 PGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP--P 1500

Query: 1482 MDINAAIQALIESNTALQMESYQ-NTEVTLIDHS---EEIFKTLNYLSNLLHSIKNPLGT 1537
             ++   +  L    T    E  Q + +  ++D+S   EEIF +LN L   +  +K P+GT
Sbjct: 1501 GEVIQPLPILSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGT 1560

Query: 1538 RDNPARICKDLLNCEQKVSDGKYWIDPNLGCPSDAIEVFCNFSAGGQTCLPPVSVTK--- 1594
            + NPAR CKDL        DG+YWIDPN GC  D+ +V+CNF++GG+TC+ P   ++   
Sbjct: 1561 QTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVR 1620

Query: 1595 -------------LEFGVGK--------------VQMNFLHLLSSEATHIITIHCLNTPR 1627
                          EF  GK              VQM FL LL++ A    T HC  +  
Sbjct: 1621 ISSWPKEKPGSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAA 1680

Query: 1628 WTSTQTSGPGLPIGFKGWNGQIFKVNTLLEPKVLSDDCKIQDGSWHKATFLFHTQEPNQL 1687
            W    +      + F G N +    +     K L D C  + G + K     +T + +Q+
Sbjct: 1681 WYDVSSGSYDKALRFLGSNDEEMSYDNNPFIKTLYDGCASRKG-YEKTVIEINTPKIDQV 1739

Query: 1688 PVIEVQKLPHLKTERKYYIDSSSVCFL 1714
            P+++V         +K+  +   VCFL
Sbjct: 1740 PIVDVMINDFGDQNQKFGFEVGPVCFL 1766



 Score =  752 bits (1941), Expect = 0.0
 Identities = 432/959 (45%), Positives = 522/959 (54%), Gaps = 87/959 (9%)

Query: 488  RGPKGDTGPPGPP------------GPAGIPGPSGKR---GPRGIPGPHGNPGLPGLPGP 532
            RG +G  GPPGPP            GP G+PG +G R   GPRG PG  G PG+ G+ GP
Sbjct: 576  RGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP 635

Query: 533  KGPKGDPGFSPGQPVP----GEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPG 588
             GPKG+ G   G+P P    G  G QGL G  GP G  G+KG +G PGL GLPG      
Sbjct: 636  PGPKGNMG-PQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD---- 690

Query: 589  FAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKG 648
                 G PG+PG++G +G +G  GP G QG IG PG  G  G +G R   G++G KG KG
Sbjct: 691  -----GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVR---GLKGSKGEKG 742

Query: 649  RQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKG 708
              GFPG  GD G  G  G  G +G  G  G  G +G  GP G  GP+G  G  G  G  G
Sbjct: 743  EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG 802

Query: 709  LPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPG 768
            LPG  G +G +G+ G  G PG  G+KGA G+ G PG RG+ GP+G  G  G +GP+G PG
Sbjct: 803  LPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG 862

Query: 769  PEGF---PGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPG 825
            P+G     G  G PG+ GP+GP+G +G  GP GPPG  G  G  G  G  GE G +GK G
Sbjct: 863  PKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 922

Query: 826  QKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGP---LG 882
              G  G  GP+G  GE G    IG+ G  GP G PGE G+ G+ G++G +G PGP    G
Sbjct: 923  PPGPGGVVGPQGPTGETGP---IGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISG 979

Query: 883  PQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLL------G 936
              G  G+ G+PG  G+PG  G  GL G  G +GPPG  G  G+RGS G  G +      G
Sbjct: 980  KDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG 1039

Query: 937  EQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRG 996
             QG  G  GEKG  G++GP G  G+ G  G  G  G  G  G PG  GD+G  GEPG +G
Sbjct: 1040 PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKG 1099

Query: 997  LQGDV---GPPGEMGMEGPPGTEGESGLQGEP---------GAKGDVGTAGSVGGTGEPG 1044
             +GD    GPPG  G++GP G  G +G  GEP         G KGD G  G  G  G  G
Sbjct: 1100 SKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIG 1159

Query: 1045 LRGEPGAPGEEGLQ---GKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPG 1101
            L+G PG PGE+G     G  G  G PG RG  G +G  G  G PG +G +G  G+ G PG
Sbjct: 1160 LQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG 1219

Query: 1102 PEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMG 1161
              G  G PG+ G  G KG++G+ G  G  G+ GPPG  G  G  G +G  G VG  G  G
Sbjct: 1220 EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG 1279

Query: 1162 PDGEP------GIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQ 1215
            P GEP      G+ G +G  G PG  G PGP GE G PG       PPG RG PG  G +
Sbjct: 1280 PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG-------PPGKRGPPGAAGAE 1332

Query: 1216 GERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLK---GERGSEGNKGKKGAP 1272
            G +GE GA+G  G  G PG  G  G QGP G+PG +G +G+    GE+G  G  G+ G P
Sbjct: 1333 GRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1392

Query: 1273 GPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAP 1332
            GP G PG+PGL+G  G KG +G+ G  G+ G PG+ G  G +GLPG +G PG  G  G P
Sbjct: 1393 GPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIP 1452

Query: 1333 GPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGE 1391
            GP G  G  G PG PG QGPKG          +G  G  G +GD G  G PG  G PGE
Sbjct: 1453 GPAGPLGPPGPPGLPGPQGPKGN---------KGSTGPAGQKGDSGLPGPPGSPGPPGE 1502



 Score =  404 bits (1039), Expect = e-112
 Identities = 243/530 (45%), Positives = 271/530 (51%), Gaps = 39/530 (7%)

Query: 487  LRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQP 546
            L+G +G  GPPGP G  G  G +G  GP G+P   G PG  G PGP G KG PG    Q 
Sbjct: 1004 LKGGEGPQGPPGPVGSPGERGSAGTAGPIGLP---GRPGPQGPPGPAGEKGAPGEKGPQG 1060

Query: 547  VPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQ---- 602
              G  G QG  GL GP G  G  G  G  G  G PG++G  G  G  G PG PG Q    
Sbjct: 1061 PAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG 1120

Query: 603  --GLAGPEGNPGPKGAQGFIGSPGEAGQL---GPEGERGIPGIRGKKGFKGRQGFPGDFG 657
              G+AG +G PGP+G QG  G  G+ G     GP G  G+ G+ G  G KG  G  G  G
Sbjct: 1121 APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMG 1180

Query: 658  DRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKG 717
              GP G  G  G  G  GP G P   GSVG VG +G  G PG  G  G  G  G+ G KG
Sbjct: 1181 PPGPPGPRGPQGPNGADGPQGPP---GSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKG 1237

Query: 718  EQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIG 777
            E+G  GE G PG  G  GA G PG  G +G  GP G  GDPG  G  GP G +G  GD G
Sbjct: 1238 ERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKG 1297

Query: 778  IPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEG 837
              G  G  GP G  G  GPPGPP      G+ GP GA G  G +G+ G KG AG  GP G
Sbjct: 1298 EDGDPGQPGPPGPSGEAGPPGPP------GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPG 1351

Query: 838  LKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPG 897
              G VG QG  GK G  G  G+PG VG  G  G  G+ G PGP+GP       G PG  G
Sbjct: 1352 KTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPP------GLPGLKG 1405

Query: 898  VPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHG 957
             PG  G  G PG +G  GPPG QG KG RG      L G QG  GAKG+ G  G  GP G
Sbjct: 1406 DPGSKGEKGHPGLIGLIGPPGEQGEKGDRG------LPGTQGSPGAKGDGGIPGPAGPLG 1459

Query: 958  LIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEM 1007
              G  G PG +G +G  G  G  G  GD GLPG P      G  GPPGE+
Sbjct: 1460 PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPP------GSPGPPGEV 1503



 Score =  318 bits (815), Expect = 3e-86
 Identities = 192/426 (45%), Positives = 219/426 (51%), Gaps = 36/426 (8%)

Query: 488  RGPKGDTGPPGPPG---PAGIPGPSG------KRGPRGIPGPHGNPGLPGLPGPKGPKGD 538
            +G KG+ GPPGPPG   P G PG +G       RG +G+ G  G+ G  G PGP GP G 
Sbjct: 1101 KGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGL 1160

Query: 539  PGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGY 598
             G  PG P  GEKG+ G  G MGPPG  G +G +G  G  G  G  G  G  G +G  G 
Sbjct: 1161 QGL-PGPP--GEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1217

Query: 599  PGRQGLAGPEGNPG---PKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGD 655
            PG  G  GP G  G   PKG +G  G  G  G  GP G +G PG  G KG  G  GFPGD
Sbjct: 1218 PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD 1277

Query: 656  FG---DRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGI 712
             G   + GPAG DG  G  G  G PG PG  G  G  GP GP G  GP G +G +G  G 
Sbjct: 1278 PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGE 1337

Query: 713  KGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPG---P 769
            KG KGE G  G  G+ G  G +G  G PGP G+RG  GP G+ G PG  G  GPPG   P
Sbjct: 1338 KGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGP 1397

Query: 770  EGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGY 829
             G PG  G PG  G +G  GL+G  GPPG  G KG +G  G  G+ G  G  G PG  G 
Sbjct: 1398 PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGP 1457

Query: 830  AGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGV 889
             G PGP GL G  G +GN                G TG  G+KG+ G PGP G  G  G 
Sbjct: 1458 LGPPGPPGLPGPQGPKGN---------------KGSTGPAGQKGDSGLPGPPGSPGPPGE 1502

Query: 890  MGYPGP 895
            +  P P
Sbjct: 1503 VIQPLP 1508



 Score =  278 bits (710), Expect = 4e-74
 Identities = 164/365 (44%), Positives = 189/365 (51%), Gaps = 27/365 (7%)

Query: 484  MEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPR---GIPGPHGNPGLPGLPGPKGPKGDPG 540
            ++ L GP G+ G  G  GP G PGP G RGP+   G  GP G PG  G  G  G KG+PG
Sbjct: 1160 LQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG 1219

Query: 541  FSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPG 600
             +      G  G  G +G+ GP G +G+KG  G PG  G PG +G PG  G  G+PG  G
Sbjct: 1220 EA------GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVG 1273

Query: 601  RQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRG 660
              G  GP G PGP G  G  G  GE G  G  G  G  G  G  G  G++G PG  G  G
Sbjct: 1274 FPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEG 1333

Query: 661  PAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQG 720
              G  G+ G  G  GPP      G  GPVGP GPAG PGP      +GL GI G  GEQG
Sbjct: 1334 RQGEKGAKGEAGAEGPP------GKTGPVGPQGPAGKPGP------EGLRGIPGPVGEQG 1381

Query: 721  TAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPG 780
              G  G+ G PG  G  GLPG   ++G  G  G+ G PGL G  GPPG +G  GD G+PG
Sbjct: 1382 LPGAAGQDGPPGPMGPPGLPG---LKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1438

Query: 781  QNGPEGPK---GLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEG 837
              G  G K   G+ G  GP GPPG  G  G +GP G  G  GP G+ G  G  G PG  G
Sbjct: 1439 TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1498

Query: 838  LKGEV 842
              GEV
Sbjct: 1499 PPGEV 1503



 Score =  135 bits (340), Expect = 3e-31
 Identities = 88/238 (36%), Positives = 110/238 (46%), Gaps = 38/238 (15%)

Query: 1272 PGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGK--IGPPGKQGLPGIRGGPGRTGLA 1329
            P     PG+P    +     I G HGA G  G  G+  +  PG      + G PG  G A
Sbjct: 358  PNEEFGPGVPAETDIT-ETSING-HGAYGEKGQKGEPAVVEPGML----VEGPPGPAGPA 411

Query: 1330 GAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQG----------KRGHRGAQGD--- 1376
            G  GPPG++G +G PG PG +GP G  GLPG  G+ G          + G  G++G    
Sbjct: 412  GIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTIS 471

Query: 1377 -----------------QGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGIS 1419
                             +GP G  GL G+PG  G  G +G +G  G  GP+G  G+ G  
Sbjct: 472  AQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP 531

Query: 1420 GPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPG 1477
            GP G  G RG  G  G  G+ G  G  G RG  G  G  G +G RG+ GP GPPG PG
Sbjct: 532  GPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 589



 Score =  131 bits (329), Expect = 6e-30
 Identities = 87/196 (44%), Positives = 100/196 (51%), Gaps = 29/196 (14%)

Query: 485  EYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPG 544
            E LRG  G  G  G PG AG  GP         PGP G PGLPGL      KGDPG    
Sbjct: 1368 EGLRGIPGPVGEQGLPGAAGQDGP---------PGPMGPPGLPGL------KGDPGSK-- 1410

Query: 545  QPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGL---PGLPGEQGIPGFAGNIGSPGYPGR 601
                GEKG  GL GL+GPPG QG+KG +G PG    PG  G+ GIPG AG +G PG PG 
Sbjct: 1411 ----GEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL 1466

Query: 602  QGLAGPEGN---PGPKGAQGFIGSPGEAGQLGPEGE--RGIPGIRGKKGFKGRQGFPGDF 656
             G  GP+GN    GP G +G  G PG  G  GP GE  + +P +  KK  +  +G   D 
Sbjct: 1467 PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADA 1526

Query: 657  GDRGPAGLDGSPGLVG 672
             D      DG   + G
Sbjct: 1527 DDNILDYSDGMEEIFG 1542



 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 63/251 (25%), Positives = 110/251 (43%), Gaps = 37/251 (14%)

Query: 88  AYIETPFVKILPVN-LGQPFTILTGLQSHRVNNAFLFSIRNKNRLQ-LGVQL--LPKKLV 143
           A +  P  ++ P     + F+IL  ++  +   +FL SI N++ +Q +GV++   P  L 
Sbjct: 80  AQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYNEHGIQQIGVEVGRSPVFLF 139

Query: 144 VHIRGKQPAVFNY------SVHDEQWHSFAITIRNQSVSMFVECGKKYFSTETIPEVQTF 197
               GK PA  +Y      ++ D +WH  AI++  ++V+M V+C KK        E    
Sbjct: 140 EDHTGK-PAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIV 198

Query: 198 DSNSVFTLGSMNNNSIHFEGIVCQLDIIPSAEASADYCRYVKQQC-----RQADKYQP-- 250
           D+N +   G+   +   FEG + Q  I    +A+ DYC +    C     + A   +P  
Sbjct: 199 DTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYSPDCDSSAPKAAQAQEPQI 258

Query: 251 ----------ETSIPCTTLIPTKIPEH-----SPPPKLFAEKVLSEDTFTEGKSIPNIIK 295
                     E +        T+ P H      P P    E++ +E+  T G+   +  K
Sbjct: 259 DEANIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNP---VEEIFTEEYLT-GEDYDSQRK 314

Query: 296 NDSETVYKRQE 306
           N  +T+Y+ +E
Sbjct: 315 NSEDTLYENKE 325


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  883 bits (2282), Expect = 0.0
 Identities = 569/1407 (40%), Positives = 682/1407 (48%), Gaps = 205/1407 (14%)

Query: 489  GPKGDTGPPGPPGPAG-IPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPV 547
            G KG  G P    P   + GP G  GP GI GP      PGL GP GP GDPG    +  
Sbjct: 423  GEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP------PGLQGPTGPPGDPG---DRGP 473

Query: 548  PGEKGDQGLSGLMGPPGMQ----------GDKG--------------------LKGHPG- 576
            PG  G  G  GL GPPG            G KG                    L+G PG 
Sbjct: 474  PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGP 533

Query: 577  --LPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGE 634
              L G PG  G PG +G  G  G PG QG  G +G PGP G  G  G PG  G  G  GE
Sbjct: 534  MGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGE 593

Query: 635  RGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGP 694
               PG +G +GF G  G PGD G RG  G  G PG      PPG  G+RG  G +GP G 
Sbjct: 594  ---PGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG------PPGDDGMRGEDGEIGPRGL 644

Query: 695  AGIPGPMGLSGNKGLPGIKGD------------KGEQGTAGELGEPGYPGDKGAVGLPGP 742
             G  GP GL G +G PG  G             KG  G  GE G PG  G+ G  GLPGP
Sbjct: 645  PGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGP 704

Query: 743  ------PGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGP 796
                  PG +G  G  G  G PG  GP G PG EG  G+ G  G  GP+GP G  G RG 
Sbjct: 705  QGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGV 764

Query: 797  PGPP---GLKGTQGEEGP------IGAFGELGPRGKPGQKGYAGEPGPEGLKGE---VGD 844
             G     GLKG++GE+G        G  G  G RG+ GQ G  GE GPEG KG     GD
Sbjct: 765  KGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGD 824

Query: 845  QGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGP 904
             G  G+ GE G +G+PG  G  G  G KG  G PG  G  GEKG  G  G PG  G  GP
Sbjct: 825  PGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP 884

Query: 905  LGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGN 964
             G  G  GARGP G  GPKG  G  GP G  GE+G QG +G  G  G +GP G  GK G 
Sbjct: 885  TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL 944

Query: 965  P------GERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGE 1018
            P      GE GFQGK G  G  G  G +G  GE G  G +G  GPPG  G +G PG  G+
Sbjct: 945  PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 1004

Query: 1019 SGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGE--- 1075
             G +G+PG +G  G  G  G  G PG RG PGA G  GL+G +G +G PG  G PGE   
Sbjct: 1005 EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGS 1064

Query: 1076 ------------------DGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGK 1117
                               G  GE G PG  GP G +G+ G+ GP G+ G  G  G PG+
Sbjct: 1065 AGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGE 1124

Query: 1118 KGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEP----------- 1166
             GDKG+IG  G+ GS+G     G++GP G  G +G VG  G+ G DGEP           
Sbjct: 1125 DGDKGEIGEPGQKGSKGDK---GENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQ 1181

Query: 1167 -GIPGYRGHQGQPGP---SGLPGPKGEKGYPGEDSTV--LGPPGPRGEPGPVGDQGERGE 1220
             G  G RG  G PGP    GLPGP GEKG  G+   +   GPPGPRG  GP G  G +G 
Sbjct: 1182 KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGP 1241

Query: 1221 PGAEGYKGHVGVPGLRGATGQQGPPGEP---GDQGEQGLKGE------------RGSEGN 1265
            PG+ G  G VG  G  G  G  GPPGE    G +GE+G KGE            +G  G+
Sbjct: 1242 PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGD 1301

Query: 1266 KGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQ------GLPGI 1319
             G KG PGP G PG PG  G  GP G  G  G  G  G+PG+ GPPG        G PG 
Sbjct: 1302 DGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGK 1361

Query: 1320 RGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGP 1379
            RG PG  G  G  G  G KG +G  G PG  GP G QG  G+PG +G RG  G  G+QG 
Sbjct: 1362 RGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGL 1421

Query: 1380 CGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGN--------- 1430
             G  G  G PG  G  GL G +G PG KG +G  G++G+ GP G  G +G+         
Sbjct: 1422 PGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGS 1481

Query: 1431 ---------TGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQ 1481
                      GP G  G  GP G  GP+G KG +G TGP G +G  G PGPPG+PGP   
Sbjct: 1482 PGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP--P 1539

Query: 1482 MDINAAIQALIESNTALQMESYQ-NTEVTLIDHS---EEIFKTLNYLSNLLHSIKNPLGT 1537
             ++   +  L    T    E  Q + +  ++D+S   EEIF +LN L   +  +K P+GT
Sbjct: 1540 GEVIQPLPILSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGT 1599

Query: 1538 RDNPARICKDLLNCEQKVSDGKYWIDPNLGCPSDAIEVFCNFSAGGQTCLPPVSVTK--- 1594
            + NPAR CKDL        DG+YWIDPN GC  D+ +V+CNF++GG+TC+ P   ++   
Sbjct: 1600 QTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVR 1659

Query: 1595 -------------LEFGVGK--------------VQMNFLHLLSSEATHIITIHCLNTPR 1627
                          EF  GK              VQM FL LL++ A    T HC  +  
Sbjct: 1660 ISSWPKEKPGSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAA 1719

Query: 1628 WTSTQTSGPGLPIGFKGWNGQIFKVNTLLEPKVLSDDCKIQDGSWHKATFLFHTQEPNQL 1687
            W    +      + F G N +    +     K L D C  + G + K     +T + +Q+
Sbjct: 1720 WYDVSSGSYDKALRFLGSNDEEMSYDNNPFIKTLYDGCASRKG-YEKTVIEINTPKIDQV 1778

Query: 1688 PVIEVQKLPHLKTERKYYIDSSSVCFL 1714
            P+++V         +K+  +   VCFL
Sbjct: 1779 PIVDVMINDFGDQNQKFGFEVGPVCFL 1805



 Score =  752 bits (1941), Expect = 0.0
 Identities = 432/959 (45%), Positives = 522/959 (54%), Gaps = 87/959 (9%)

Query: 488  RGPKGDTGPPGPP------------GPAGIPGPSGKR---GPRGIPGPHGNPGLPGLPGP 532
            RG +G  GPPGPP            GP G+PG +G R   GPRG PG  G PG+ G+ GP
Sbjct: 615  RGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP 674

Query: 533  KGPKGDPGFSPGQPVP----GEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPG 588
             GPKG+ G   G+P P    G  G QGL G  GP G  G+KG +G PGL GLPG      
Sbjct: 675  PGPKGNMG-PQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD---- 729

Query: 589  FAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKG 648
                 G PG+PG++G +G +G  GP G QG IG PG  G  G +G R   G++G KG KG
Sbjct: 730  -----GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVR---GLKGSKGEKG 781

Query: 649  RQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKG 708
              GFPG  GD G  G  G  G +G  G  G  G +G  GP G  GP+G  G  G  G  G
Sbjct: 782  EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG 841

Query: 709  LPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPG 768
            LPG  G +G +G+ G  G PG  G+KGA G+ G PG RG+ GP+G  G  G +GP+G PG
Sbjct: 842  LPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG 901

Query: 769  PEGF---PGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPG 825
            P+G     G  G PG+ GP+GP+G +G  GP GPPG  G  G  G  G  GE G +GK G
Sbjct: 902  PKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 961

Query: 826  QKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGP---LG 882
              G  G  GP+G  GE G    IG+ G  GP G PGE G+ G+ G++G +G PGP    G
Sbjct: 962  PPGPGGVVGPQGPTGETGP---IGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISG 1018

Query: 883  PQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLL------G 936
              G  G+ G+PG  G+PG  G  GL G  G +GPPG  G  G+RGS G  G +      G
Sbjct: 1019 KDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG 1078

Query: 937  EQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRG 996
             QG  G  GEKG  G++GP G  G+ G  G  G  G  G  G PG  GD+G  GEPG +G
Sbjct: 1079 PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKG 1138

Query: 997  LQGDV---GPPGEMGMEGPPGTEGESGLQGEP---------GAKGDVGTAGSVGGTGEPG 1044
             +GD    GPPG  G++GP G  G +G  GEP         G KGD G  G  G  G  G
Sbjct: 1139 SKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIG 1198

Query: 1045 LRGEPGAPGEEGLQ---GKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPG 1101
            L+G PG PGE+G     G  G  G PG RG  G +G  G  G PG +G +G  G+ G PG
Sbjct: 1199 LQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG 1258

Query: 1102 PEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMG 1161
              G  G PG+ G  G KG++G+ G  G  G+ GPPG  G  G  G +G  G VG  G  G
Sbjct: 1259 EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG 1318

Query: 1162 PDGEP------GIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQ 1215
            P GEP      G+ G +G  G PG  G PGP GE G PG       PPG RG PG  G +
Sbjct: 1319 PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG-------PPGKRGPPGAAGAE 1371

Query: 1216 GERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLK---GERGSEGNKGKKGAP 1272
            G +GE GA+G  G  G PG  G  G QGP G+PG +G +G+    GE+G  G  G+ G P
Sbjct: 1372 GRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1431

Query: 1273 GPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAP 1332
            GP G PG+PGL+G  G KG +G+ G  G+ G PG+ G  G +GLPG +G PG  G  G P
Sbjct: 1432 GPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIP 1491

Query: 1333 GPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGE 1391
            GP G  G  G PG PG QGPKG          +G  G  G +GD G  G PG  G PGE
Sbjct: 1492 GPAGPLGPPGPPGLPGPQGPKGN---------KGSTGPAGQKGDSGLPGPPGSPGPPGE 1541



 Score =  404 bits (1039), Expect = e-112
 Identities = 243/530 (45%), Positives = 271/530 (51%), Gaps = 39/530 (7%)

Query: 487  LRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQP 546
            L+G +G  GPPGP G  G  G +G  GP G+P   G PG  G PGP G KG PG    Q 
Sbjct: 1043 LKGGEGPQGPPGPVGSPGERGSAGTAGPIGLP---GRPGPQGPPGPAGEKGAPGEKGPQG 1099

Query: 547  VPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQ---- 602
              G  G QG  GL GP G  G  G  G  G  G PG++G  G  G  G PG PG Q    
Sbjct: 1100 PAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG 1159

Query: 603  --GLAGPEGNPGPKGAQGFIGSPGEAGQL---GPEGERGIPGIRGKKGFKGRQGFPGDFG 657
              G+AG +G PGP+G QG  G  G+ G     GP G  G+ G+ G  G KG  G  G  G
Sbjct: 1160 APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMG 1219

Query: 658  DRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKG 717
              GP G  G  G  G  GP G P   GSVG VG +G  G PG  G  G  G  G+ G KG
Sbjct: 1220 PPGPPGPRGPQGPNGADGPQGPP---GSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKG 1276

Query: 718  EQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIG 777
            E+G  GE G PG  G  GA G PG  G +G  GP G  GDPG  G  GP G +G  GD G
Sbjct: 1277 ERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKG 1336

Query: 778  IPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEG 837
              G  G  GP G  G  GPPGPP      G+ GP GA G  G +G+ G KG AG  GP G
Sbjct: 1337 EDGDPGQPGPPGPSGEAGPPGPP------GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPG 1390

Query: 838  LKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPG 897
              G VG QG  GK G  G  G+PG VG  G  G  G+ G PGP+GP       G PG  G
Sbjct: 1391 KTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPP------GLPGLKG 1444

Query: 898  VPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHG 957
             PG  G  G PG +G  GPPG QG KG RG      L G QG  GAKG+ G  G  GP G
Sbjct: 1445 DPGSKGEKGHPGLIGLIGPPGEQGEKGDRG------LPGTQGSPGAKGDGGIPGPAGPLG 1498

Query: 958  LIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEM 1007
              G  G PG +G +G  G  G  G  GD GLPG P      G  GPPGE+
Sbjct: 1499 PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPP------GSPGPPGEV 1542



 Score =  318 bits (815), Expect = 3e-86
 Identities = 192/426 (45%), Positives = 219/426 (51%), Gaps = 36/426 (8%)

Query: 488  RGPKGDTGPPGPPG---PAGIPGPSG------KRGPRGIPGPHGNPGLPGLPGPKGPKGD 538
            +G KG+ GPPGPPG   P G PG +G       RG +G+ G  G+ G  G PGP GP G 
Sbjct: 1140 KGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGL 1199

Query: 539  PGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGY 598
             G  PG P  GEKG+ G  G MGPPG  G +G +G  G  G  G  G  G  G +G  G 
Sbjct: 1200 QGL-PGPP--GEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1256

Query: 599  PGRQGLAGPEGNPG---PKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGD 655
            PG  G  GP G  G   PKG +G  G  G  G  GP G +G PG  G KG  G  GFPGD
Sbjct: 1257 PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD 1316

Query: 656  FG---DRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGI 712
             G   + GPAG DG  G  G  G PG PG  G  G  GP GP G  GP G +G +G  G 
Sbjct: 1317 PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGE 1376

Query: 713  KGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPG---P 769
            KG KGE G  G  G+ G  G +G  G PGP G+RG  GP G+ G PG  G  GPPG   P
Sbjct: 1377 KGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGP 1436

Query: 770  EGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGY 829
             G PG  G PG  G +G  GL+G  GPPG  G KG +G  G  G+ G  G  G PG  G 
Sbjct: 1437 PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGP 1496

Query: 830  AGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGV 889
             G PGP GL G  G +GN                G TG  G+KG+ G PGP G  G  G 
Sbjct: 1497 LGPPGPPGLPGPQGPKGN---------------KGSTGPAGQKGDSGLPGPPGSPGPPGE 1541

Query: 890  MGYPGP 895
            +  P P
Sbjct: 1542 VIQPLP 1547



 Score =  278 bits (710), Expect = 4e-74
 Identities = 164/365 (44%), Positives = 189/365 (51%), Gaps = 27/365 (7%)

Query: 484  MEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPR---GIPGPHGNPGLPGLPGPKGPKGDPG 540
            ++ L GP G+ G  G  GP G PGP G RGP+   G  GP G PG  G  G  G KG+PG
Sbjct: 1199 LQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG 1258

Query: 541  FSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPG 600
             +      G  G  G +G+ GP G +G+KG  G PG  G PG +G PG  G  G+PG  G
Sbjct: 1259 EA------GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVG 1312

Query: 601  RQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRG 660
              G  GP G PGP G  G  G  GE G  G  G  G  G  G  G  G++G PG  G  G
Sbjct: 1313 FPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEG 1372

Query: 661  PAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQG 720
              G  G+ G  G  GPP      G  GPVGP GPAG PGP      +GL GI G  GEQG
Sbjct: 1373 RQGEKGAKGEAGAEGPP------GKTGPVGPQGPAGKPGP------EGLRGIPGPVGEQG 1420

Query: 721  TAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPG 780
              G  G+ G PG  G  GLPG   ++G  G  G+ G PGL G  GPPG +G  GD G+PG
Sbjct: 1421 LPGAAGQDGPPGPMGPPGLPG---LKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1477

Query: 781  QNGPEGPK---GLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEG 837
              G  G K   G+ G  GP GPPG  G  G +GP G  G  GP G+ G  G  G PG  G
Sbjct: 1478 TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1537

Query: 838  LKGEV 842
              GEV
Sbjct: 1538 PPGEV 1542



 Score =  135 bits (340), Expect = 3e-31
 Identities = 88/238 (36%), Positives = 110/238 (46%), Gaps = 38/238 (15%)

Query: 1272 PGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGK--IGPPGKQGLPGIRGGPGRTGLA 1329
            P     PG+P    +     I G HGA G  G  G+  +  PG      + G PG  G A
Sbjct: 397  PNEEFGPGVPAETDIT-ETSING-HGAYGEKGQKGEPAVVEPGML----VEGPPGPAGPA 450

Query: 1330 GAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQG----------KRGHRGAQGD--- 1376
            G  GPPG++G +G PG PG +GP G  GLPG  G+ G          + G  G++G    
Sbjct: 451  GIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTIS 510

Query: 1377 -----------------QGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGIS 1419
                             +GP G  GL G+PG  G  G +G +G  G  GP+G  G+ G  
Sbjct: 511  AQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP 570

Query: 1420 GPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPG 1477
            GP G  G RG  G  G  G+ G  G  G RG  G  G  G +G RG+ GP GPPG PG
Sbjct: 571  GPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 628



 Score =  131 bits (329), Expect = 6e-30
 Identities = 87/196 (44%), Positives = 100/196 (51%), Gaps = 29/196 (14%)

Query: 485  EYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPG 544
            E LRG  G  G  G PG AG  GP         PGP G PGLPGL      KGDPG    
Sbjct: 1407 EGLRGIPGPVGEQGLPGAAGQDGP---------PGPMGPPGLPGL------KGDPGSK-- 1449

Query: 545  QPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGL---PGLPGEQGIPGFAGNIGSPGYPGR 601
                GEKG  GL GL+GPPG QG+KG +G PG    PG  G+ GIPG AG +G PG PG 
Sbjct: 1450 ----GEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL 1505

Query: 602  QGLAGPEGN---PGPKGAQGFIGSPGEAGQLGPEGE--RGIPGIRGKKGFKGRQGFPGDF 656
             G  GP+GN    GP G +G  G PG  G  GP GE  + +P +  KK  +  +G   D 
Sbjct: 1506 PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADA 1565

Query: 657  GDRGPAGLDGSPGLVG 672
             D      DG   + G
Sbjct: 1566 DDNILDYSDGMEEIFG 1581



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 65/270 (24%), Positives = 117/270 (43%), Gaps = 24/270 (8%)

Query: 88  AYIETPFVKILPVN-LGQPFTILTGLQSHRVNNAFLFSIRNKNRLQ-LGVQL--LPKKLV 143
           A +  P  ++ P     + F+IL  ++  +   +FL SI N++ +Q +GV++   P  L 
Sbjct: 80  AQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYNEHGIQQIGVEVGRSPVFLF 139

Query: 144 VHIRGKQPAVFNY------SVHDEQWHSFAITIRNQSVSMFVECGKKYFSTETIPEVQTF 197
               GK PA  +Y      ++ D +WH  AI++  ++V+M V+C KK        E    
Sbjct: 140 EDHTGK-PAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIV 198

Query: 198 DSNSVFTLGSMNNNSIHFEGIVCQLDIIPSAEASADYCRYVKQQCRQADKYQPETSIPCT 257
           D+N +   G+   +   FEG + Q  I    +A+ DYC +    C  +     +   P  
Sbjct: 199 DTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYSPDCDSSAPKAAQAQEP-- 256

Query: 258 TLIPTKIPEHSPPPKLFAEKVLSEDTFTEGKSIPNIIKNDSETVYKRQEHQISRSQ---- 313
                +I E++P   +  +    E  + E +S+        ET+ + + + +   Q    
Sbjct: 257 -----QIDEYAPEDIIEYDYEYGEAEYKEAESVTEGPTVTEETIAQTEANIVDDFQEYNY 311

Query: 314 --LSSLQSGNVSAVDLTNHGIQAKEMITEE 341
             + S Q+     V  TN     +E+ TEE
Sbjct: 312 GTMESYQTEAPRHVSGTNEPNPVEEIFTEE 341


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  813 bits (2099), Expect = 0.0
 Identities = 501/1148 (43%), Positives = 586/1148 (51%), Gaps = 161/1148 (14%)

Query: 484  MEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGP---HGNPGLPGLPGPK------- 533
            M  L GPKG+ G PGPPG  G+PGP+G  GP G PGP    G PG PGLPGPK       
Sbjct: 163  MSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNF 222

Query: 534  -GPKGDPGFS-----PGQP-----------VPGEKGDQGLSGLMGPP------------- 563
             GPKG+ G       PG P           V  +KGDQGL G  GPP             
Sbjct: 223  QGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG 282

Query: 564  ------GMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQ 617
                  G QG+ G +G PG  G  G+ GIPG  G+ G PG PGR G  G +G+ GP G  
Sbjct: 283  GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPP 342

Query: 618  GF-IGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPG--LVGGT 674
            G  I  PG    +G +G  G+PG+ G+   KG +GFP   G +GP GL G PG  ++G  
Sbjct: 343  GLVIPRPGTGITIGEKGNIGLPGLPGE---KGERGFP---GIQGPPGLPGPPGAAVMGPP 396

Query: 675  GPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQG----------TAGE 724
            GPPGFPG RG  G  GP G   IPGP GL G  G PG+ G  G  G            G 
Sbjct: 397  GPPGFPGERGQKGDEGPPG-ISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP 455

Query: 725  LGEPGYPGDKGAVGLPGPPGMRGK-------SGPSGQTGDPGLQGPSGPPGPEGFPGDIG 777
             G PG PGDKG  G  G  G +G        +G SG  G PGL G  GPPG  GFPG  G
Sbjct: 456  PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKG 515

Query: 778  IPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAF-------GELGPRGKPGQKGYA 830
              GQ G  GPKGL G  G PG PG  G++GE G I  F       GELG  G PG  G  
Sbjct: 516  EKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLP 575

Query: 831  GEPGPEGLKGEVGDQGNIGKI---GETGPVGLPGEVGMTGSIGEKGER--GSPGPLGPQG 885
            G PG +GL G  G +G  G I   GE GP G PG  G+ G+IG  G    G PGP+G +G
Sbjct: 576  GTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKG 635

Query: 886  EKGVMGYPGPPGVPGPIGPLG----LPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQ 941
             +GV G PG PG+PGP G  G     PG  G  G PG  G  G  G  G  G  G  GI 
Sbjct: 636  IQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIP 695

Query: 942  GAKGEKGD-----QGKRGPHGL------IGKTGNPGERGFQGKPGLQGLPGSTGDRGL-- 988
            G+KGE G       G  GP G        G  G PG  G +G PG  G PG  G+ G   
Sbjct: 696  GSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755

Query: 989  ---PGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGL 1045
               PG PGL G +G +GP G+ G  GPPG  G +GL G PG KGDVG  G  G  G PGL
Sbjct: 756  PGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL 815

Query: 1046 -----RGEPGAPGEEGLQGKDGLKGVPGGRG--------LPGEDGEKGEMGLPGIIGPLG 1092
                 +G PG PG  G  G+ GL G+PG +G        +PG  GE+G  G+PG  GP+G
Sbjct: 816  PGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIG 875

Query: 1093 RSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPK------G 1146
              G  GLPG  G  G PG +G  G  G  G  GP G  G  G PG  G  G +      G
Sbjct: 876  PPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPG 935

Query: 1147 ARGTRGAVGHLGLMGPDG--EPGIPGYRGHQGQPGPSGLP---GPKGEKGYPGEDST--- 1198
              G +G+ G  GL GP G  +P + G +G +G+PG  G+P   GPKG +G PG+      
Sbjct: 936  PTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGL 995

Query: 1199 -----VLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGE 1253
                 + GPPGP+G PG  G  G  G PG +G  G +G PG +G  G  GP G PG  G 
Sbjct: 996  SGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGS 1055

Query: 1254 QGLKGERGSEGNK-----GKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKI 1308
             GL G++G +G+      G  G PGP G+PG+PG  G  G KG  G  G  G+ G PG  
Sbjct: 1056 PGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAK 1115

Query: 1309 GPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGS---PGIQGPKGEQGLPGQPGIQ 1365
            G PG  G PG  G PG  G++G PG PG+ G  G  G    PG  GP GE+G PGQ GI 
Sbjct: 1116 GQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIP 1175

Query: 1366 GKRGHRGAQ-----GDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISG 1420
            G  G +G       G+ GP G PGL GQ G+ G+ G+ G  G PGPKG  G  G  G+ G
Sbjct: 1176 GPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQG 1235

Query: 1421 PKGPIGHRGNT--GPLGREGIIGPTGRTGPRGEKGFRGETGP---------QGPRGQPGP 1469
            P GP G  G    GP G  G  GP GR GP G +G  G  GP         +G +G PG 
Sbjct: 1236 PPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQ 1295

Query: 1470 PGPPGAPG 1477
            PG PG PG
Sbjct: 1296 PGLPGLPG 1303



 Score =  805 bits (2079), Expect = 0.0
 Identities = 491/1096 (44%), Positives = 577/1096 (52%), Gaps = 122/1096 (11%)

Query: 487  LRGPKGDTGPPG-----PPGPAGIPGPSGKRGPRG-----IPGP---HGNPGLPGLPGPK 533
            ++GP G  GPPG     PPGP G PG  G++G  G     IPGP    G PG PGLPGP 
Sbjct: 378  IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPP 437

Query: 534  GPKGDPGFSPGQPV-----PGEKGDQGLSGLMGPPGMQGDKGLKGH----PGLPGLPGEQ 584
            GP G P   P   +     PG  G  G  GL G  G++GDKG         G+ G PG+ 
Sbjct: 438  GPAG-PHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQP 496

Query: 585  GIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERG----IPGI 640
            G+PG  G  GS G+PG++G  G  G  GPKG  G  G+PG  G  G +GE G     PG+
Sbjct: 497  GLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGM 556

Query: 641  RGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTG------------PPGFPGLRGSVGP 688
            +G KG  G  G PG  G  G  G DG PGL G  G            PPG PGL G  G 
Sbjct: 557  KGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGN 616

Query: 689  VGPIGPAGI--PGPMG------LSGNKGLPGIKGDKGEQGTA----GELGEPGYPGDKGA 736
            +GP+GP G   PGP+G      ++GN G PGI G KG+ G      G+ G PG PG  G 
Sbjct: 617  IGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGD 676

Query: 737  VGLPGPPGMRGKSGPSG---QTGDPGLQGPS--GPPGPEGFPGDIGIPGQ---------N 782
            VGLPG PG+ G+ G  G     G+PG+ G    GPPGP+GFPG  G PG           
Sbjct: 677  VGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLE 736

Query: 783  GPEGPKGLLGNRG--------PPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPG 834
            GP GP G  G +G        PPGPPGL G +G  GP G  G  GP G PG+ G  G PG
Sbjct: 737  GPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPG 796

Query: 835  PEGLKGEVGDQG--------NIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLG---- 882
            P+G  G  G  G         IG  G  GP G+PG +G  G  G  GE+G PGP G    
Sbjct: 797  PKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVP 856

Query: 883  -PQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQ 941
             P GE+G  G PG PG  GP G  GLPG  GA G PG++G  G  G  GP G LG  G  
Sbjct: 857  GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS 916

Query: 942  GAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQG-----LPGSTGDRGLPGEPGLRG 996
            G  G KGD G +G  GL G TG  G +G  G PG  G     L GS G++G PG PG+ G
Sbjct: 917  GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPG 976

Query: 997  LQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRG---EPGAPG 1053
            + G  G  G  G  G PG  G+ GL G PG KG+ G  G  G  G PGL+G   + G PG
Sbjct: 977  VSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG 1036

Query: 1054 EEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRG 1113
             +G++G  G  GVPG  G PG  G+KG+ G PGI       G  GLPGP+G  G+PG   
Sbjct: 1037 PQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI----SSIGLPGLPGPKGEPGLPGY-- 1090

Query: 1114 RPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRG 1173
             PG  G KG +G  G  G  G PG  G+ G  G  GT G  G  G+ GP G PG+PG  G
Sbjct: 1091 -PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPG 1149

Query: 1174 HQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGP--VGDQGERGEPGAEGYKGHVG 1231
              G  G  G PGP GEKG PG+D  + GP G +GEPG    G+ G  G PG  G KG  G
Sbjct: 1150 PVGGGGHPGQPGPPGEKGKPGQDG-IPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGG 1208

Query: 1232 VPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGN-----KGKKGAPGPSGKPGIPGLQGL 1286
            +PG+ G  G  GP GEPG  G  G++G  G  G+     +G KG PGP G PG PG    
Sbjct: 1209 LPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPG---- 1264

Query: 1287 LGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGS 1346
              P G QG  G +G  G PG  G  G++G PG  G PG  GL G  GPPG++G+   PG 
Sbjct: 1265 --PTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGN---PGR 1319

Query: 1347 PGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTG----FQG 1402
            PG+ G KG+ GLPG PG  G +G  G  G  GP G+PGL G PG  G+ G +G     +G
Sbjct: 1320 PGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKG 1379

Query: 1403 FPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQG 1462
              GP G  G  G+ G+ GP+GP G  G TGP G  G  G  G  G  G KG  G  G  G
Sbjct: 1380 DAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPG 1439

Query: 1463 PRGQPGPPGPPGAPGP 1478
             RG  GPPGP G  GP
Sbjct: 1440 TRGLDGPPGPDGLQGP 1455



 Score =  785 bits (2028), Expect = 0.0
 Identities = 482/1144 (42%), Positives = 564/1144 (49%), Gaps = 175/1144 (15%)

Query: 499  PPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLSG 558
            P       G  G++G RG PG  G+PGLPG PGP+GP G  G      +PG  G +G+ G
Sbjct: 34   PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRG 93

Query: 559  LMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQG 618
              G PG  G  GL G PG  G PG QGIPG  G  G  G+PG  G  G +G PGP G  G
Sbjct: 94   PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPG 153

Query: 619  FIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPG 678
              G PG        G +G PG  G  G    QG PG  G  GP G  G PGL+G  GPPG
Sbjct: 154  MKGEPGSIIMSSLPGPKGNPGYPGPPGI---QGLPGPTGIPGPIGPPGPPGLMGPPGPPG 210

Query: 679  FPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPG----------IKGDKGEQGTAGELGEP 728
             PG +G++G +   GP G  G  GL G  G PG          ++  KG+QG  G+ G P
Sbjct: 211  LPGPKGNMG-LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPP 269

Query: 729  GYPGDKGAVGLP-GPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGP 787
            G PG +G  G P G  G +G+ G  G+ G PG  G +G PG  G PGD G PG+ G +G 
Sbjct: 270  GPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGE 329

Query: 788  KGLLGNRGPPGPP-------------------GLKGTQGEEGPIGAFGELGPRGKPGQKG 828
            KG  G+ GPPGPP                   GL G  GE+G  G  G  GP G PG  G
Sbjct: 330  KGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG 389

Query: 829  YA--GEPGPEGLKGEVGDQGNIGKIGET--GPVGLPGEVGMTGSIGEKG----------- 873
             A  G PGP G  GE G +G+ G  G +  GP GL G+ G  G  G  G           
Sbjct: 390  AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449

Query: 874  --ERGSPGPLGPQGEKGVM-------------------------GYPGPPGVPGPIGPLG 906
              E G PGP G  G+KG+                          G PG PG+PGP G LG
Sbjct: 450  ICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLG 509

Query: 907  LPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQG----------IQGAKGEKGDQGKRGPH 956
             PG  G +G  G+ GPKG  G  G  G  G  G            G KG+KG+ G  G  
Sbjct: 510  FPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAP 569

Query: 957  GLIGKTGNPGERGFQGKPGLQGLPGS---TGDRGLPGEPGLRGLQGDVGPPGEMGMEGPP 1013
            GL G  G PG+ G  G PG +G PG     G+RG PG PGL GL G++GP G  G  GPP
Sbjct: 570  GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPP 628

Query: 1014 GTEGESGLQGE---------PGAKGDVGTA----------GSVGGTGEPGLRGEPGAPGE 1054
            G  GE G+QG          PG KGD G            G+ G  G+ GL G+PG PG+
Sbjct: 629  GPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQ 688

Query: 1055 EGLQGKDGLKGVPG--GRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQR 1112
             GL G  G KG PG  G GLPG  G KG  G+PG  G  G  G+ GL GP G  G PG +
Sbjct: 689  PGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPK 748

Query: 1113 GR-----------PGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMG 1161
            G            PG  G KG +GP G+ G  GPPG  G++G  G  G +G VG  G  G
Sbjct: 749  GEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPG 808

Query: 1162 PDGEPGIPGYRGHQGQPGPSGLPGP---------KGEKGYPGEDS-TVLGPPGPRGEPGP 1211
            P G PG+PG  G QG PGP G+PGP          GEKG PG     V GPPG RG PG 
Sbjct: 809  PMGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGI 867

Query: 1212 VGDQGERGEPGAEGYKGHVGV---PGLRGATGQQGPPGEPGD------------------ 1250
             G  G  G PG+ G  G  G    PG +G  G  GPPG PG                   
Sbjct: 868  PGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGL 927

Query: 1251 QGEQGLKGERGSEGNKGKKGAPGP--------------SGKPGIPGLQGLLGPKGIQGY- 1295
            QG+ GL G  G +G+KG+ G PGP               G+PG+PG+ G+ GPKG QG  
Sbjct: 928  QGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLP 987

Query: 1296 --HGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPK 1353
               G  G+SG PG  GPPG +G PG+   PG+ GL G PG  G  G  G PG  G++GP 
Sbjct: 988  GDPGQPGLSGQPGLPGPPGPKGNPGL---PGQPGLIGPPGLKGTIGDMGFPGPQGVEGPP 1044

Query: 1354 GEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDA 1413
            G  G+PGQPG  G  G +G +GD G     GL G PG  G  GL G+ G PG KG  GD 
Sbjct: 1045 GPSGVPGQPGSPGLPGQKGDKGDPG-ISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP 1103

Query: 1414 GIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPP 1473
            G+ G+ G  G  G  G  G  G  G  GP G +GP G  G  GE GP G  G PG PGPP
Sbjct: 1104 GLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPP 1163

Query: 1474 GAPG 1477
            G  G
Sbjct: 1164 GEKG 1167



 Score =  733 bits (1892), Expect = 0.0
 Identities = 458/1069 (42%), Positives = 542/1069 (50%), Gaps = 160/1069 (14%)

Query: 548  PGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGP 607
            PG K D   SG+ G  G +G  GL+GHPGLPG PG +G PG  G  G  G PG  G   P
Sbjct: 34   PGSKCD--CSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPG---P 88

Query: 608  EGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGS 667
            +G  GP G  GF G+PG            +PG+ G  G  G QG PG  G +G  G  GS
Sbjct: 89   KGIRGPPGLPGFPGTPG------------LPGMPGHDGAPGPQGIPGCNGTKGERGFPGS 136

Query: 668  PGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGE 727
            PG  G  GPPG PG+ G  G  G I  + +PGP G  G  G PGI+G  G  G  G +G 
Sbjct: 137  PGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGP 196

Query: 728  PGYPGDKGAVGLPGPPGMRGK-----SGPSGQTGDPGLQGPSGPPGP----------EGF 772
            PG PG  G  G PG PG +G       GP G+ G+ GLQGP GPPG           E  
Sbjct: 197  PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQ 256

Query: 773  PGDIGIPGQNGPEGPKGLLGNRGPPGPPG-LKGTQGEEGPIGAFGELGPRGKPGQKGYAG 831
             GD G+PG  GP GP G+   RGPPGPPG  KG +GE+G  G  G+ G  G+ GQ G  G
Sbjct: 257  KGDQGLPGDRGPPGPPGI---RGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPG 313

Query: 832  EPGPEGLKGEVGDQGNIGKIGETGPVGLPGEV----GMTGSIGEKGERGSPGPLGPQGEK 887
             PG  G  GE G  G  G+ G+TGP G PG V    G   +IGEKG  G PG  G +GE+
Sbjct: 314  LPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGER 373

Query: 888  GVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLL-----GEQGIQG 942
            G  G  GPPG+PGP G   +    G  GPPG  G +GQ+G  GP G+      G  G  G
Sbjct: 374  GFPGIQGPPGLPGPPGAAVM----GPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPG 429

Query: 943  AKGEKGDQGKRGPH----------GLIGKTGNPGERGFQGK------------------- 973
            A G  G  G  GPH          G  G  G+PG++G QG+                   
Sbjct: 430  APGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGI 489

Query: 974  ------PGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGA 1027
                  PGL GLPG  G  G PG+ G +G  G  GP G  G+ G PG  G  G +GEPG 
Sbjct: 490  SGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGD 549

Query: 1028 ----KGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMG 1083
                 G  G  G +G  G PGL G PG PG++GL G  G KG PGG    GE G  G  G
Sbjct: 550  ILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPG 609

Query: 1084 LPGIIGPLGRSGQTGL--PGP------EGIVGIPGQRGRPGKKGDKGQI----------- 1124
            LPG+ G +G  G  G   PGP      +G+ G PGQ G PG KGD GQ            
Sbjct: 610  LPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669

Query: 1125 --GPTGEVGSRGPPGKIGKSGPKGARGTRGAVG--------------HLGLMGPDGEPGI 1168
              G  G+VG  G PG  G+ G  G  G++G  G                G+ GP G PG 
Sbjct: 670  NPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGT 729

Query: 1169 PGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPG---PVGDQGERGEPGAEG 1225
            PG  G +G PGP G PGPKGE G+      + GPPGP G PG    +G +G+RG PG  G
Sbjct: 730  PGRIGLEGPPGPPGFPGPKGEPGF-----ALPGPPGPPGLPGFKGALGPKGDRGFPGPPG 784

Query: 1226 YKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPG---IPG 1282
              G  G+ GL G  G  GP G+PG  G  GL G  G +G  G  G PGP G+PG   IPG
Sbjct: 785  PPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPG 843

Query: 1283 LQGLLGPKGIQ-----GYHGADGISGNPGKIGPPGKQGLPGIRGG---PGRTGLAGAPGP 1334
             +G  GP G+      G  G+ GI G PG IGPPG  GLPG  G    PG  G  G  GP
Sbjct: 844  EKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP 903

Query: 1335 PGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCG-----DPGLKGQP 1389
            PG  G  G+PG  G+ G KG+ GL GQPG+ G  G +G++G+ G  G     DP L G  
Sbjct: 904  PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSK 963

Query: 1390 GEYGVQGLTGFQGFPGPKGPEG---DAGIVGISGPKG---PIGHRGNTGPLGREGIIGPT 1443
            GE G  GL G  G  GPKG +G   D G  G+SG  G   P G +GN G  G+ G+IGP 
Sbjct: 964  GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPP 1023

Query: 1444 GRTGPRGEKGFRGETGPQGPRG------QPGPPGPPGAPGPRKQMDINA 1486
            G  G  G+ GF G  G +GP G      QPG PG PG  G +    I++
Sbjct: 1024 GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISS 1072



 Score =  709 bits (1830), Expect = 0.0
 Identities = 428/927 (46%), Positives = 491/927 (52%), Gaps = 61/927 (6%)

Query: 477  DLNTMLEMEYLRGPKGDTGPPGPPGPAGIPGPS---GKRGPRGIP---------GPHGNP 524
            D+ T   M+  +G  G  G PG PG  G PG     G  GP+G P         GP GNP
Sbjct: 549  DILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNP 608

Query: 525  GLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKG----HPGLPGL 580
            GLPGLPG  GP G PGF P  PV GEKG QG++G  G PG+ G KG  G     PG PGL
Sbjct: 609  GLPGLPGNIGPMGPPGFGPPGPV-GEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGL 667

Query: 581  PGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGI 640
            PG  G  G  G  G PG PG+ GL G  G+ G  G  G IG PG     GP+G  GIPG 
Sbjct: 668  PGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPG-IGLPGPP---GPKGFPGIPGP 723

Query: 641  RGKKGFKGRQGFPGDFGDRGPAGLDGSPG--LVGGTGPPGFPGLRGSVGPVGPIGPAGIP 698
             G  G  GR G  G  G  G  G  G PG  L G  GPPG PG +G++GP G  G  G P
Sbjct: 724  PGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPP 783

Query: 699  GPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDP 758
            GP G +G  GLPG KGD G  G  G +G PG PG  G  G PGPPG+ G  G  G  G P
Sbjct: 784  GPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG-IGVQGPPGPPGIPGPIGQPGLHGIP 842

Query: 759  GLQGPSGP-----PGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIG 813
            G +G  GP     PGP G  G  GIPG  GP GP G  G  G  G  G  GT+GE G +G
Sbjct: 843  GEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMG 902

Query: 814  AFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVG-----MTGS 868
              G  GP G PG+ G  G  G +GL+G+ G  G  G+ G  G  GLPG  G     + GS
Sbjct: 903  PPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGS 962

Query: 869  IGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGS 928
             GEKGE G PG  G  G KG  G PG PG PG  G  GLPG  G +G PG  G  G  G 
Sbjct: 963  KGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGP 1022

Query: 929  RGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKP-----GLQGLPGST 983
             G  G +G+ G  G +G +G  G  G  G  G  G PG++G +G P     GL GLPG  
Sbjct: 1023 PGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPK 1082

Query: 984  GDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEP 1043
            G+ GLPG PG  G++G VG PG  G+ G PG +G+ GL G PG  G  G  G  G  G P
Sbjct: 1083 GEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNP 1142

Query: 1044 GLRGEP---GAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLP 1100
            GL GEP   G  G  G  G  G KG PG  G+PG  G+KGE G PG   P G  G  GL 
Sbjct: 1143 GLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNP-GPPGLPGLS 1201

Query: 1101 GPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLM 1160
            G +G  G+PG  G PG  G KG+ G  G  G +GPPG  G  GP       G  G+ G  
Sbjct: 1202 GQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP----ALEGPKGNPGPQ 1257

Query: 1161 GPDGEPGIPGYRGHQGQPGPSGLPGP---KGEKGYPGEDSTVLGPPGPRGEPGPVGDQGE 1217
            GP G PG  G++G  G  GP GLPG    KGEKG PG+   + G PG +G+ GP G QG 
Sbjct: 1258 GPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPG-LPGLPGLKGDQGPPGLQGN 1316

Query: 1218 RGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGK 1277
             G PG  G KG  G+PG+ G  G +GP G PG  G +   GE G  G  G  G PGPSG+
Sbjct: 1317 PGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPE---GEPGLIGPPGPPGLPGPSGQ 1373

Query: 1278 -------PGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAG 1330
                    G PG+ G  G KG+ G  G  G+ G  G  G PG+ GLPG  G  GR G  G
Sbjct: 1374 SIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPG 1433

Query: 1331 APGPPGVKGSSGLPGSPGIQGPKGEQG 1357
             PG PG +G  G PG  G+QGP G  G
Sbjct: 1434 LPGQPGTRGLDGPPGPDGLQGPPGPPG 1460



 Score =  451 bits (1161), Expect = e-126
 Identities = 281/628 (44%), Positives = 320/628 (50%), Gaps = 53/628 (8%)

Query: 488  RGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPV 547
            +G  G  GPPGPPGP GIPG SG  G +G  G  G PGLPG  G KG KG+PG  PG P 
Sbjct: 895  KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGL-PGPPG 953

Query: 548  P---------GEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGY 598
            P         GEKG+ GL G+ G  G +G +GL G PG PGL G+ G+PG  G  G+PG 
Sbjct: 954  PMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGL 1013

Query: 599  PGRQGLAGP------------------EGNPGPKGAQGFIGSPGEAGQLGPEGERGI--- 637
            PG+ GL GP                  EG PGP G  G  GSPG  GQ G +G+ GI   
Sbjct: 1014 PGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSI 1073

Query: 638  --PGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPA 695
              PG+ G KG  G  G+PG+ G +G  G  G PGL G  G  G PGL G  G  GP GP 
Sbjct: 1074 GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPK 1133

Query: 696  GIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSG-- 753
            GI GP    GN GLPG  G  G  G  G+ G PG  G  G  G+PGP G +G+ G  G  
Sbjct: 1134 GISGP---PGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFG 1190

Query: 754  ---QTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEG 810
                 G PGL G  G  G  G PG+ G+PG  G  G  G  G +GPPGPPG  G    EG
Sbjct: 1191 NPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP-ALEG 1249

Query: 811  PIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIG 870
            P G  G  GP G+PG  G+ G PGPEG  G  G+ G  G+ G  G  GLPG  G+ G  G
Sbjct: 1250 PKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQG 1309

Query: 871  EKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRG 930
              G +G+PG  G  G KG  G PG PG PG  GP G+PG  G  G PG  GP G  G  G
Sbjct: 1310 PPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPG 1369

Query: 931  PDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPG 990
            P G    Q I      KGD G  G  G  G  G PG +G QG PG  G PG  G  GLPG
Sbjct: 1370 PSG----QSII----IKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPG 1421

Query: 991  EPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPG 1050
              G  G +GD G PG+ G  G  G  G  GLQG PG  G    A     T        P 
Sbjct: 1422 FDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQ 1481

Query: 1051 APGEEGLQGKDG--LKGVPGGRGLPGED 1076
             P +  LQ  +G  L  V G +   G+D
Sbjct: 1482 CP-QGTLQVYEGFSLLYVQGNKRAHGQD 1508



 Score =  192 bits (488), Expect = 2e-48
 Identities = 112/226 (49%), Positives = 126/226 (55%), Gaps = 18/226 (7%)

Query: 487  LRGPKGDTGPPGPP---GPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSP 543
            L GPKG+ GP GPP   GP G          +G+PGP G PGLPG  G KG KG+PG  P
Sbjct: 1247 LEGPKGNPGPQGPPGRPGPTGF---------QGLPGPEGPPGLPGNGGIKGEKGNPG-QP 1296

Query: 544  GQP-VPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQ 602
            G P +PG KGDQG  GL G PG  G  G+KG PGLPG+PG  G+ G +G  GS G  G  
Sbjct: 1297 GLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEP 1356

Query: 603  GLAGPEGNPGPKGAQG----FIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGD 658
            GL GP G PG  G  G      G  G  G  G  G +G+PG +G +G  G  G PGD G 
Sbjct: 1357 GLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGR 1416

Query: 659  RGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLS 704
             G  G DG+ G  G  G PG PG RG  GP GP G  G PGP G S
Sbjct: 1417 NGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTS 1462


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score =  811 bits (2095), Expect = 0.0
 Identities = 499/1145 (43%), Positives = 584/1145 (51%), Gaps = 158/1145 (13%)

Query: 484  MEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGP---HGNPGLPGLPGPK------- 533
            M  L GPKG+ G PGPPG  G+PGP+G  GP G PGP    G PG PGLPGPK       
Sbjct: 163  MSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNF 222

Query: 534  -GPKGDPGFS-----PGQP-----------VPGEKGDQGLSGLMGPP------------- 563
             GPKG+ G       PG P           V  +KGDQGL G  GPP             
Sbjct: 223  QGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG 282

Query: 564  ------GMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQ 617
                  G QG+ G +G PG  G  G+ GIPG  G+ G PG PGR G  G +G+ GP G  
Sbjct: 283  GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPP 342

Query: 618  GF-IGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPG--LVGGT 674
            G  I  PG    +G +G  G+PG+ G+   KG +GFP   G +GP GL G PG  ++G  
Sbjct: 343  GLVIPRPGTGITIGEKGNIGLPGLPGE---KGERGFP---GIQGPPGLPGPPGAAVMGPP 396

Query: 675  GPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQG----------TAGE 724
            GPPGFPG RG  G  GP G   IPGP GL G  G PG+ G  G  G            G 
Sbjct: 397  GPPGFPGERGQKGDEGPPG-ISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP 455

Query: 725  LGEPGYPGDKGAVGLPGPPGMRGK-------SGPSGQTGDPGLQGPSGPPGPEGFPGDIG 777
             G PG PGDKG  G  G  G +G        +G SG  G PGL G  GPPG  GFPG  G
Sbjct: 456  PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKG 515

Query: 778  IPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAF-------GELGPRGKPGQKGYA 830
              GQ G  GPKGL G  G PG PG  G++GE G I  F       GELG  G PG  G  
Sbjct: 516  EKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLP 575

Query: 831  GEPGPEGLKGEVGDQGNIGKI---GETGPVGLPGEVGMTGSIGEKGER--GSPGPLGPQG 885
            G PG +GL G  G +G  G I   GE GP G PG  G+ G+IG  G    G PGP+G +G
Sbjct: 576  GTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKG 635

Query: 886  EKGVMGYPGPPGVPGPIGPLG----LPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQ 941
             +GV G PG PG+PGP G  G     PG  G  G PG  G  G  G  G  G  G  GI 
Sbjct: 636  IQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIP 695

Query: 942  GAKGEKGD-----QGKRGPHGL------IGKTGNPGERGFQGKPGLQGLPGSTGDRGL-- 988
            G+KGE G       G  GP G        G  G PG  G +G PG  G PG  G+ G   
Sbjct: 696  GSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755

Query: 989  ---PGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGL 1045
               PG PGL G +G +GP G+ G  GPPG  G +GL G PG KGDVG  G  G  G PGL
Sbjct: 756  PGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL 815

Query: 1046 -----RGEPGAPGEEGLQGKDGLKGVPGGRG--------LPGEDGEKGEMGLPGIIGPLG 1092
                 +G PG PG  G  G+ GL G+PG +G        +PG  GE+G  G+PG  GP+G
Sbjct: 816  PGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIG 875

Query: 1093 RSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPK------G 1146
              G  GLPG  G  G PG +G  G  G  G  GP G  G  G PG  G  G +      G
Sbjct: 876  PPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPG 935

Query: 1147 ARGTRGAVGHLGLMGPDG--EPGIPGYRGHQGQPGPSGLP---GPKGEKGYPGEDST--- 1198
              G +G+ G  GL GP G  +P + G +G +G+PG  G+P   GPKG +G PG+      
Sbjct: 936  PTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGL 995

Query: 1199 -----VLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGE 1253
                 + GPPGP+G PG  G  G  G PG +G  G +G PG +G  G  GP G PG  G 
Sbjct: 996  SGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGS 1055

Query: 1254 QGLKGERGSEGNK-----GKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKI 1308
             GL G++G +G+      G  G PGP G+PG+PG  G  G KG  G  G  G+ G PG  
Sbjct: 1056 PGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAK 1115

Query: 1309 GPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGS---PGIQGPKGEQGLPGQPGIQ 1365
            G PG  G PG  G PG  G++G PG PG+ G  G  G    PG  GP GE+G PGQ GI 
Sbjct: 1116 GQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIP 1175

Query: 1366 GKRGHRGAQ-----GDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISG 1420
            G  G +G       G+ GP G PGL GQ G+ G+ G+ G  G PGPKG  G  G  G+ G
Sbjct: 1176 GPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQG 1235

Query: 1421 PKGPIGH--------RGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGP 1472
            P GP G         +GN GP G  G  G  G  GP G  G  G  G +G +G PG PG 
Sbjct: 1236 PPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGL 1295

Query: 1473 PGAPG 1477
            PG PG
Sbjct: 1296 PGLPG 1300



 Score =  810 bits (2092), Expect = 0.0
 Identities = 490/1095 (44%), Positives = 574/1095 (52%), Gaps = 122/1095 (11%)

Query: 487  LRGPKGDTGPPG-----PPGPAGIPGPSGKRGPRG-----IPGP---HGNPGLPGLPGPK 533
            ++GP G  GPPG     PPGP G PG  G++G  G     IPGP    G PG PGLPGP 
Sbjct: 378  IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPP 437

Query: 534  GPKGDPGFSPGQPV-----PGEKGDQGLSGLMGPPGMQGDKGLKGH----PGLPGLPGEQ 584
            GP G P   P   +     PG  G  G  GL G  G++GDKG         G+ G PG+ 
Sbjct: 438  GPAG-PHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQP 496

Query: 585  GIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERG----IPGI 640
            G+PG  G  GS G+PG++G  G  G  GPKG  G  G+PG  G  G +GE G     PG+
Sbjct: 497  GLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGM 556

Query: 641  RGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTG------------PPGFPGLRGSVGP 688
            +G KG  G  G PG  G  G  G DG PGL G  G            PPG PGL G  G 
Sbjct: 557  KGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGN 616

Query: 689  VGPIGPAGI--PGPMG------LSGNKGLPGIKGDKGEQGTA----GELGEPGYPGDKGA 736
            +GP+GP G   PGP+G      ++GN G PGI G KG+ G      G+ G PG PG  G 
Sbjct: 617  IGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGD 676

Query: 737  VGLPGPPGMRGKSGPSG---QTGDPGLQGPS--GPPGPEGFPGDIGIPGQ---------N 782
            VGLPG PG+ G+ G  G     G+PG+ G    GPPGP+GFPG  G PG           
Sbjct: 677  VGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLE 736

Query: 783  GPEGPKGLLGNRG--------PPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPG 834
            GP GP G  G +G        PPGPPGL G +G  GP G  G  GP G PG+ G  G PG
Sbjct: 737  GPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPG 796

Query: 835  PEGLKGEVGDQG--------NIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLG---- 882
            P+G  G  G  G         IG  G  GP G+PG +G  G  G  GE+G PGP G    
Sbjct: 797  PKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVP 856

Query: 883  -PQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQ 941
             P GE+G  G PG PG  GP G  GLPG  GA G PG++G  G  G  GP G LG  G  
Sbjct: 857  GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS 916

Query: 942  GAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQG-----LPGSTGDRGLPGEPGLRG 996
            G  G KGD G +G  GL G TG  G +G  G PG  G     L GS G++G PG PG+ G
Sbjct: 917  GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPG 976

Query: 997  LQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRG---EPGAPG 1053
            + G  G  G  G  G PG  G+ GL G PG KG+ G  G  G  G PGL+G   + G PG
Sbjct: 977  VSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG 1036

Query: 1054 EEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRG 1113
             +G++G  G  GVPG  G PG  G+KG+ G PGI       G  GLPGP+G  G+PG   
Sbjct: 1037 PQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI----SSIGLPGLPGPKGEPGLPGY-- 1090

Query: 1114 RPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRG 1173
             PG  G KG +G  G  G  G PG  G+ G  G  GT G  G  G+ GP G PG+PG  G
Sbjct: 1091 -PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPG 1149

Query: 1174 HQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGP--VGDQGERGEPGAEGYKGHVG 1231
              G  G  G PGP GEKG PG+D  + GP G +GEPG    G+ G  G PG  G KG  G
Sbjct: 1150 PVGGGGHPGQPGPPGEKGKPGQDG-IPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGG 1208

Query: 1232 VPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGN-----KGKKGAPGPSGKPGIPGLQGL 1286
            +PG+ G  G  GP GEPG  G  G++G  G  G+     +G KG PGP G PG PG QGL
Sbjct: 1209 LPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGL 1268

Query: 1287 LGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGS 1346
             GP+G  G  G  GI G  G  G PG  GLPG++G  G  GL G PG PG+ G  G PG 
Sbjct: 1269 PGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGL 1328

Query: 1347 PGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPG-------LKGQPGEYGVQGLTG 1399
            PG+ G  G +G  G PG  G  G  G  G  GP G PG       +KG  G  G+ G  G
Sbjct: 1329 PGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPG 1388

Query: 1400 FQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETG 1459
             +G PGP+GP+      G+ GP GP G  G  G  G +G  G  G  G  G+ G RG  G
Sbjct: 1389 LKGLPGPQGPQ------GLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDG 1442

Query: 1460 PQGPRGQPGPPGPPG 1474
            P GP G  GPPGPPG
Sbjct: 1443 PPGPDGLQGPPGPPG 1457



 Score =  785 bits (2028), Expect = 0.0
 Identities = 482/1144 (42%), Positives = 564/1144 (49%), Gaps = 175/1144 (15%)

Query: 499  PPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLSG 558
            P       G  G++G RG PG  G+PGLPG PGP+GP G  G      +PG  G +G+ G
Sbjct: 34   PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRG 93

Query: 559  LMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQG 618
              G PG  G  GL G PG  G PG QGIPG  G  G  G+PG  G  G +G PGP G  G
Sbjct: 94   PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPG 153

Query: 619  FIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPG 678
              G PG        G +G PG  G  G    QG PG  G  GP G  G PGL+G  GPPG
Sbjct: 154  MKGEPGSIIMSSLPGPKGNPGYPGPPGI---QGLPGPTGIPGPIGPPGPPGLMGPPGPPG 210

Query: 679  FPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPG----------IKGDKGEQGTAGELGEP 728
             PG +G++G +   GP G  G  GL G  G PG          ++  KG+QG  G+ G P
Sbjct: 211  LPGPKGNMG-LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPP 269

Query: 729  GYPGDKGAVGLP-GPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGP 787
            G PG +G  G P G  G +G+ G  G+ G PG  G +G PG  G PGD G PG+ G +G 
Sbjct: 270  GPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGE 329

Query: 788  KGLLGNRGPPGPP-------------------GLKGTQGEEGPIGAFGELGPRGKPGQKG 828
            KG  G+ GPPGPP                   GL G  GE+G  G  G  GP G PG  G
Sbjct: 330  KGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG 389

Query: 829  YA--GEPGPEGLKGEVGDQGNIGKIGET--GPVGLPGEVGMTGSIGEKG----------- 873
             A  G PGP G  GE G +G+ G  G +  GP GL G+ G  G  G  G           
Sbjct: 390  AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449

Query: 874  --ERGSPGPLGPQGEKGVM-------------------------GYPGPPGVPGPIGPLG 906
              E G PGP G  G+KG+                          G PG PG+PGP G LG
Sbjct: 450  ICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLG 509

Query: 907  LPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQG----------IQGAKGEKGDQGKRGPH 956
             PG  G +G  G+ GPKG  G  G  G  G  G            G KG+KG+ G  G  
Sbjct: 510  FPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAP 569

Query: 957  GLIGKTGNPGERGFQGKPGLQGLPGS---TGDRGLPGEPGLRGLQGDVGPPGEMGMEGPP 1013
            GL G  G PG+ G  G PG +G PG     G+RG PG PGL GL G++GP G  G  GPP
Sbjct: 570  GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPP 628

Query: 1014 GTEGESGLQGE---------PGAKGDVGTA----------GSVGGTGEPGLRGEPGAPGE 1054
            G  GE G+QG          PG KGD G            G+ G  G+ GL G+PG PG+
Sbjct: 629  GPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQ 688

Query: 1055 EGLQGKDGLKGVPG--GRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQR 1112
             GL G  G KG PG  G GLPG  G KG  G+PG  G  G  G+ GL GP G  G PG +
Sbjct: 689  PGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPK 748

Query: 1113 GR-----------PGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMG 1161
            G            PG  G KG +GP G+ G  GPPG  G++G  G  G +G VG  G  G
Sbjct: 749  GEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPG 808

Query: 1162 PDGEPGIPGYRGHQGQPGPSGLPGP---------KGEKGYPGEDS-TVLGPPGPRGEPGP 1211
            P G PG+PG  G QG PGP G+PGP          GEKG PG     V GPPG RG PG 
Sbjct: 809  PMGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGI 867

Query: 1212 VGDQGERGEPGAEGYKGHVGV---PGLRGATGQQGPPGEPGD------------------ 1250
             G  G  G PG+ G  G  G    PG +G  G  GPPG PG                   
Sbjct: 868  PGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGL 927

Query: 1251 QGEQGLKGERGSEGNKGKKGAPGP--------------SGKPGIPGLQGLLGPKGIQGY- 1295
            QG+ GL G  G +G+KG+ G PGP               G+PG+PG+ G+ GPKG QG  
Sbjct: 928  QGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLP 987

Query: 1296 --HGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPK 1353
               G  G+SG PG  GPPG +G PG+   PG+ GL G PG  G  G  G PG  G++GP 
Sbjct: 988  GDPGQPGLSGQPGLPGPPGPKGNPGL---PGQPGLIGPPGLKGTIGDMGFPGPQGVEGPP 1044

Query: 1354 GEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDA 1413
            G  G+PGQPG  G  G +G +GD G     GL G PG  G  GL G+ G PG KG  GD 
Sbjct: 1045 GPSGVPGQPGSPGLPGQKGDKGDPG-ISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP 1103

Query: 1414 GIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPP 1473
            G+ G+ G  G  G  G  G  G  G  GP G +GP G  G  GE GP G  G PG PGPP
Sbjct: 1104 GLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPP 1163

Query: 1474 GAPG 1477
            G  G
Sbjct: 1164 GEKG 1167



 Score =  733 bits (1892), Expect = 0.0
 Identities = 458/1069 (42%), Positives = 542/1069 (50%), Gaps = 160/1069 (14%)

Query: 548  PGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGP 607
            PG K D   SG+ G  G +G  GL+GHPGLPG PG +G PG  G  G  G PG  G   P
Sbjct: 34   PGSKCD--CSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPG---P 88

Query: 608  EGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGS 667
            +G  GP G  GF G+PG            +PG+ G  G  G QG PG  G +G  G  GS
Sbjct: 89   KGIRGPPGLPGFPGTPG------------LPGMPGHDGAPGPQGIPGCNGTKGERGFPGS 136

Query: 668  PGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGE 727
            PG  G  GPPG PG+ G  G  G I  + +PGP G  G  G PGI+G  G  G  G +G 
Sbjct: 137  PGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGP 196

Query: 728  PGYPGDKGAVGLPGPPGMRGK-----SGPSGQTGDPGLQGPSGPPGP----------EGF 772
            PG PG  G  G PG PG +G       GP G+ G+ GLQGP GPPG           E  
Sbjct: 197  PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQ 256

Query: 773  PGDIGIPGQNGPEGPKGLLGNRGPPGPPG-LKGTQGEEGPIGAFGELGPRGKPGQKGYAG 831
             GD G+PG  GP GP G+   RGPPGPPG  KG +GE+G  G  G+ G  G+ GQ G  G
Sbjct: 257  KGDQGLPGDRGPPGPPGI---RGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPG 313

Query: 832  EPGPEGLKGEVGDQGNIGKIGETGPVGLPGEV----GMTGSIGEKGERGSPGPLGPQGEK 887
             PG  G  GE G  G  G+ G+TGP G PG V    G   +IGEKG  G PG  G +GE+
Sbjct: 314  LPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGER 373

Query: 888  GVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLL-----GEQGIQG 942
            G  G  GPPG+PGP G   +    G  GPPG  G +GQ+G  GP G+      G  G  G
Sbjct: 374  GFPGIQGPPGLPGPPGAAVM----GPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPG 429

Query: 943  AKGEKGDQGKRGPH----------GLIGKTGNPGERGFQGK------------------- 973
            A G  G  G  GPH          G  G  G+PG++G QG+                   
Sbjct: 430  APGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGI 489

Query: 974  ------PGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGA 1027
                  PGL GLPG  G  G PG+ G +G  G  GP G  G+ G PG  G  G +GEPG 
Sbjct: 490  SGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGD 549

Query: 1028 ----KGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMG 1083
                 G  G  G +G  G PGL G PG PG++GL G  G KG PGG    GE G  G  G
Sbjct: 550  ILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPG 609

Query: 1084 LPGIIGPLGRSGQTGL--PGP------EGIVGIPGQRGRPGKKGDKGQI----------- 1124
            LPG+ G +G  G  G   PGP      +G+ G PGQ G PG KGD GQ            
Sbjct: 610  LPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669

Query: 1125 --GPTGEVGSRGPPGKIGKSGPKGARGTRGAVG--------------HLGLMGPDGEPGI 1168
              G  G+VG  G PG  G+ G  G  G++G  G                G+ GP G PG 
Sbjct: 670  NPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGT 729

Query: 1169 PGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPG---PVGDQGERGEPGAEG 1225
            PG  G +G PGP G PGPKGE G+      + GPPGP G PG    +G +G+RG PG  G
Sbjct: 730  PGRIGLEGPPGPPGFPGPKGEPGF-----ALPGPPGPPGLPGFKGALGPKGDRGFPGPPG 784

Query: 1226 YKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPG---IPG 1282
              G  G+ GL G  G  GP G+PG  G  GL G  G +G  G  G PGP G+PG   IPG
Sbjct: 785  PPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPG 843

Query: 1283 LQGLLGPKGIQ-----GYHGADGISGNPGKIGPPGKQGLPGIRGG---PGRTGLAGAPGP 1334
             +G  GP G+      G  G+ GI G PG IGPPG  GLPG  G    PG  G  G  GP
Sbjct: 844  EKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP 903

Query: 1335 PGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCG-----DPGLKGQP 1389
            PG  G  G+PG  G+ G KG+ GL GQPG+ G  G +G++G+ G  G     DP L G  
Sbjct: 904  PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSK 963

Query: 1390 GEYGVQGLTGFQGFPGPKGPEG---DAGIVGISGPKG---PIGHRGNTGPLGREGIIGPT 1443
            GE G  GL G  G  GPKG +G   D G  G+SG  G   P G +GN G  G+ G+IGP 
Sbjct: 964  GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPP 1023

Query: 1444 GRTGPRGEKGFRGETGPQGPRG------QPGPPGPPGAPGPRKQMDINA 1486
            G  G  G+ GF G  G +GP G      QPG PG PG  G +    I++
Sbjct: 1024 GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISS 1072



 Score =  707 bits (1826), Expect = 0.0
 Identities = 428/927 (46%), Positives = 490/927 (52%), Gaps = 64/927 (6%)

Query: 477  DLNTMLEMEYLRGPKGDTGPPGPPGPAGIPGPS---GKRGPRGIP---------GPHGNP 524
            D+ T   M+  +G  G  G PG PG  G PG     G  GP+G P         GP GNP
Sbjct: 549  DILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNP 608

Query: 525  GLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKG----HPGLPGL 580
            GLPGLPG  GP G PGF P  PV GEKG QG++G  G PG+ G KG  G     PG PGL
Sbjct: 609  GLPGLPGNIGPMGPPGFGPPGPV-GEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGL 667

Query: 581  PGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGI 640
            PG  G  G  G  G PG PG+ GL G  G+ G  G  G IG PG     GP+G  GIPG 
Sbjct: 668  PGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPG-IGLPGPP---GPKGFPGIPGP 723

Query: 641  RGKKGFKGRQGFPGDFGDRGPAGLDGSPG--LVGGTGPPGFPGLRGSVGPVGPIGPAGIP 698
             G  G  GR G  G  G  G  G  G PG  L G  GPPG PG +G++GP G  G  G P
Sbjct: 724  PGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPP 783

Query: 699  GPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDP 758
            GP G +G  GLPG KGD G  G  G +G PG PG  G  G PGPPG+ G  G  G  G P
Sbjct: 784  GPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG-IGVQGPPGPPGIPGPIGQPGLHGIP 842

Query: 759  GLQGPSGP-----PGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIG 813
            G +G  GP     PGP G  G  GIPG  GP GP G  G  G  G  G  GT+GE G +G
Sbjct: 843  GEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMG 902

Query: 814  AFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVG-----MTGS 868
              G  GP G PG+ G  G  G +GL+G+ G  G  G+ G  G  GLPG  G     + GS
Sbjct: 903  PPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGS 962

Query: 869  IGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGS 928
             GEKGE G PG  G  G KG  G PG PG PG  G  GLPG  G +G PG  G  G  G 
Sbjct: 963  KGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGP 1022

Query: 929  RGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKP-----GLQGLPGST 983
             G  G +G+ G  G +G +G  G  G  G  G  G PG++G +G P     GL GLPG  
Sbjct: 1023 PGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPK 1082

Query: 984  GDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEP 1043
            G+ GLPG PG  G++G VG PG  G+ G PG +G+ GL G PG  G  G  G  G  G P
Sbjct: 1083 GEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNP 1142

Query: 1044 GLRGEP---GAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLP 1100
            GL GEP   G  G  G  G  G KG PG  G+PG  G+KGE G PG   P G  G  GL 
Sbjct: 1143 GLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNP-GPPGLPGLS 1201

Query: 1101 GPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLM 1160
            G +G  G+PG  G PG  G KG+ G  G  G +GPPG  G  GP          G  G  
Sbjct: 1202 GQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP-------ALEGPKGNP 1254

Query: 1161 GPDGEPGIPGYRGHQGQPGPSGLPGP---KGEKGYPGEDSTVLGPPGPRGEPGPVGDQGE 1217
            GP G PG PG++G  G  GP GLPG    KGEKG PG+   + G PG +G+ GP G QG 
Sbjct: 1255 GPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPG-LPGLPGLKGDQGPPGLQGN 1313

Query: 1218 RGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGK 1277
             G PG  G KG  G+PG+ G  G +GP G PG  G +   GE G  G  G  G PGPSG+
Sbjct: 1314 PGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPE---GEPGLIGPPGPPGLPGPSGQ 1370

Query: 1278 -------PGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAG 1330
                    G PG+ G  G KG+ G  G  G+ G  G  G PG+ GLPG  G  GR G  G
Sbjct: 1371 SIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPG 1430

Query: 1331 APGPPGVKGSSGLPGSPGIQGPKGEQG 1357
             PG PG +G  G PG  G+QGP G  G
Sbjct: 1431 LPGQPGTRGLDGPPGPDGLQGPPGPPG 1457



 Score =  447 bits (1150), Expect = e-125
 Identities = 279/628 (44%), Positives = 319/628 (50%), Gaps = 56/628 (8%)

Query: 488  RGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPV 547
            +G  G  GPPGPPGP GIPG SG  G +G  G  G PGLPG  G KG KG+PG  PG P 
Sbjct: 895  KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGL-PGPPG 953

Query: 548  P---------GEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGY 598
            P         GEKG+ GL G+ G  G +G +GL G PG PGL G+ G+PG  G  G+PG 
Sbjct: 954  PMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGL 1013

Query: 599  PGRQGLAGP------------------EGNPGPKGAQGFIGSPGEAGQLGPEGERGI--- 637
            PG+ GL GP                  EG PGP G  G  GSPG  GQ G +G+ GI   
Sbjct: 1014 PGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSI 1073

Query: 638  --PGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPA 695
              PG+ G KG  G  G+PG+ G +G  G  G PGL G  G  G PGL G  G  GP GP 
Sbjct: 1074 GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPK 1133

Query: 696  GIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSG-- 753
            GI GP    GN GLPG  G  G  G  G+ G PG  G  G  G+PGP G +G+ G  G  
Sbjct: 1134 GISGP---PGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFG 1190

Query: 754  ---QTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEG 810
                 G PGL G  G  G  G PG+ G+PG  G  G  G  G +GPPGPPG  G   E  
Sbjct: 1191 NPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALE-- 1248

Query: 811  PIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIG 870
              G  G  GP+G PG+ G+ G PGPEG  G  G+ G  G+ G  G  GLPG  G+ G  G
Sbjct: 1249 --GPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQG 1306

Query: 871  EKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRG 930
              G +G+PG  G  G KG  G PG PG PG  GP G+PG  G  G PG  GP G  G  G
Sbjct: 1307 PPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPG 1366

Query: 931  PDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPG 990
            P G    Q I      KGD G  G  G  G  G PG +G QG PG  G PG  G  GLPG
Sbjct: 1367 PSG----QSII----IKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPG 1418

Query: 991  EPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPG 1050
              G  G +GD G PG+ G  G  G  G  GLQG PG  G    A     T        P 
Sbjct: 1419 FDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQ 1478

Query: 1051 APGEEGLQGKDG--LKGVPGGRGLPGED 1076
             P +  LQ  +G  L  V G +   G+D
Sbjct: 1479 CP-QGTLQVYEGFSLLYVQGNKRAHGQD 1505


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score =  806 bits (2083), Expect = 0.0
 Identities = 486/1054 (46%), Positives = 557/1054 (52%), Gaps = 85/1054 (8%)

Query: 487  LRGPKGDTGPPG-----PPGPAGIPGPSGKRGPRG-----IPGP---HGNPGLPGLPGPK 533
            ++GP G  GPPG     PPGP G PG  G++G  G     IPGP    G PG PGLPGP 
Sbjct: 378  IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPP 437

Query: 534  GPKGDPGFSPGQPV-----PGEKGDQGLSGLMGPPGMQGDKGLKGH----PGLPGLPGEQ 584
            GP G P   P   +     PG  G  G  GL G  G++GDKG         G+ G PG+ 
Sbjct: 438  GPAG-PHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQP 496

Query: 585  GIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERG----IPGI 640
            G+PG  G  GS G+PG++G  G  G  GPKG  G  G+PG  G  G +GE G     PG+
Sbjct: 497  GLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGM 556

Query: 641  RGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGP 700
            +G KG  G  G PG  G  G  G DG PGL G  G PG    +G  GP G  G  G+PG 
Sbjct: 557  KGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGN 616

Query: 701  MGLSGNKGL--PGIKGDKGEQGTAGELGEPGYPGDKG-------AVGLPGPPGMRGKSGP 751
            +G  G  G   PG  G+KG QG AG  G+PG PG KG         G PG PG  G+ G 
Sbjct: 617  IGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGD 676

Query: 752  SGQTGDPGLQGPSGPPGPEGFPGDIGIPGQN--GPEGPKGLLGNRGPPGPPGLKGTQGEE 809
             G  GDPGL G  G PG  G  G+ GIPG    GP GPKG  G  GPPG PG  G  G E
Sbjct: 677  VGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLE 736

Query: 810  GPIGAFGELGPRGKPG--QKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTG 867
            GP G  G  GP+G+PG    G  G PG  G KG +G +G+ G  G  GP G  G  G+ G
Sbjct: 737  GPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPG 796

Query: 868  SIGEKGERGSPGPLGPQGEKG--VMGYPGPPGVPGPIGPLGL---PGHVGARGPPGSQ-- 920
              G+ G  G PGP+GP G  G  V G PGPPG+PGPIG  GL   PG  G  GPPG    
Sbjct: 797  PKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVP 856

Query: 921  GPKGQRGSRGPDGL---LGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQ 977
            GP G+RGS G  G    +G  G  G  G+ G  G  G  G +G  G PG  G  G PG  
Sbjct: 857  GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS 916

Query: 978  GLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGT-----------EGESGLQGEPG 1026
            G+PG  GD GL G+PGL G  G+ G  GE G+ GPPG            +GE GL G PG
Sbjct: 917  GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPG 976

Query: 1027 AKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPG 1086
              G  G  G  G  G+PGL G+PG PG  G +G  GL G PG  G PG  G  G+MG PG
Sbjct: 977  VSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG 1036

Query: 1087 IIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQ--IGPTGEVGSRGPPGKIGKSGP 1144
                    G  G PGP G+ G PG  G PG+KGDKG   I   G  G  GP G+ G  G 
Sbjct: 1037 ------PQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGY 1090

Query: 1145 KGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPG 1204
             G  G +G+VG  GL G  G PG  G  G  G PG  G PGPKG  G PG        PG
Sbjct: 1091 PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGN-------PG 1143

Query: 1205 PRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEG 1264
              GEPGPVG  G  G+PG  G KG  G  G+ G  GQ+G PG+PG        G  G  G
Sbjct: 1144 LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF-------GNPGPPG 1196

Query: 1265 NKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPG 1324
              G  G  G  G PGIPG  GL GPKG  G+HG  G+ G PG  G PG   L G +G PG
Sbjct: 1197 LPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP-ALEGPKGNPG 1255

Query: 1325 RTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPG 1384
              G  G PG PG +G  GLPG+ GI+G KG  G PG PG+ G +G +G  G QG  G PG
Sbjct: 1256 PQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPG 1315

Query: 1385 LKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGII-GPT 1443
            L G  G+ G+ G+ GF G  GP G  G AG  G  G  GP G  G  GP G+  II G  
Sbjct: 1316 LNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDA 1375

Query: 1444 GRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPG 1477
            G  G  G+ G +G  GPQGP+G PGP GPPG PG
Sbjct: 1376 GPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPG 1409



 Score =  795 bits (2052), Expect = 0.0
 Identities = 509/1200 (42%), Positives = 591/1200 (49%), Gaps = 212/1200 (17%)

Query: 484  MEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHG---NPGLPGLPGPKG------ 534
            M  L GPKG+ G PGPPG  G+PGP+G  GP G PGP G    PG PGLPGPKG      
Sbjct: 163  MSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNF 222

Query: 535  --PKGDPGFSPGQPVPG----------------EKGDQGLSGLMGPPGM----------- 565
              PKG+ G    Q  PG                +KGDQGL G  GPPG            
Sbjct: 223  QGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG 282

Query: 566  --------QGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQ 617
                    QG+ G +G PG  G  G+ GIPG  G+ G PG PGR G  G +G+ GP G  
Sbjct: 283  GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPP 342

Query: 618  GF-IGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPG--LVGGT 674
            G  I  PG    +G +G  G+PG+ G+KG    +GFPG    +GP GL G PG  ++G  
Sbjct: 343  GLVIPRPGTGITIGEKGNIGLPGLPGEKG---ERGFPGI---QGPPGLPGPPGAAVMGPP 396

Query: 675  GPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGT----------AGE 724
            GPPGFPG RG  G  GP G   IPGP GL G  G PG+ G  G  G            G 
Sbjct: 397  GPPGFPGERGQKGDEGPPG-ISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP 455

Query: 725  LGEPGYPGDKGAVGLPGPPGMRGKS-------GPSGQTGDPGLQGPSGPPGPEGFPGDIG 777
             G PG PGDKG  G  G  G +G +       G SG  G PGL G  GPPG  GFPG  G
Sbjct: 456  PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKG 515

Query: 778  IPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAF-------GELGPRGKPGQKGYA 830
              GQ G  GPKGL G  G PG PG  G++GE G I  F       GELG  G PG  G  
Sbjct: 516  EKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLP 575

Query: 831  GEPGPEGLKGEVGDQGNIGKI---GETGPVGLPGEVGMTGSIGEKGERG--SPGPLGPQG 885
            G PG +GL G  G +G  G I   GE GP G PG  G+ G+IG  G  G   PGP+G +G
Sbjct: 576  GTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKG 635

Query: 886  EKGVMGYPGPPGVPGPIGPLGL----PGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQ 941
             +GV G PG PG+PGP G  G     PG  G  G PG  G  G  G  G  G  G  GI 
Sbjct: 636  IQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIP 695

Query: 942  GAKGEKGDQG-----KRGPHGLIG------KTGNPGERGFQGKPGLQGLPGSTGDRGL-- 988
            G+KGE G  G       GP G  G        G PG  G +G PG  G PG  G+ G   
Sbjct: 696  GSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755

Query: 989  ---PGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGL 1045
               PG PGL G +G +GP G+ G  GPPG  G +GL G PG KGDVG  G  G  G PGL
Sbjct: 756  PGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL 815

Query: 1046 -----RGEPGAPGEEGLQGKDGLKGVPGGRG--------LPGEDGEKGEMGLPGIIGPLG 1092
                 +G PG PG  G  G+ GL G+PG +G        +PG  GE+G  G+PG  GP+G
Sbjct: 816  PGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIG 875

Query: 1093 RSGQTGLPG---------------------PEGIVGIPGQRGRPGKKGDKGQIG------ 1125
              G  GLPG                     P G +GIPG+ G PG KGD G  G      
Sbjct: 876  PPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPG 935

Query: 1126 PTGEVGSRGPPGKIGKSGP--------KGARGTRGAVGHLGLMGPDGE---PGIPGYRGH 1174
            PTGE GS+G PG  G  GP        KG +G  G  G  G+ GP G    PG PG  G 
Sbjct: 936  PTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGL 995

Query: 1175 QGQPGPSGLPGPKGEKGYPGEDSTV-----------LGPPGPRGEPGPVGDQGERGEPGA 1223
             GQPG  G PGPKG  G PG+   +           +G PGP+G  GP G  G  G+PG+
Sbjct: 996  SGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGS 1055

Query: 1224 EGYKGH-----------VGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAP 1272
             G  G            +G+PGL G  G+ G PG PG+ G +G  G+ G  G  G  GA 
Sbjct: 1056 PGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAK 1115

Query: 1273 GPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGP---PGKQGLPGIRGGPGRTGLA 1329
            G  G PG PG  G  GPKGI G  G  G+ G PG +G    PG+ G PG +G PG+ G+ 
Sbjct: 1116 GQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIP 1175

Query: 1330 GA--------------PGPPGVKGSSG---------LPGSPGIQGPKGEQGLPGQPGIQG 1366
            G               PGPPG+ G SG         +PG+PG+ GPKGE G  G PG+QG
Sbjct: 1176 GPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQG 1235

Query: 1367 KRGHRGA--------QGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGI 1418
              G  G+        +G+ GP G PG  G PG  G  GL G  G  G KG  G  G+ G+
Sbjct: 1236 PPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGL 1295

Query: 1419 SGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGP 1478
             G KG  G  G  G  GR G+ G  G  G  G  GF G  GP G  G  GP G PG  GP
Sbjct: 1296 PGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGP 1355



 Score =  785 bits (2028), Expect = 0.0
 Identities = 482/1144 (42%), Positives = 564/1144 (49%), Gaps = 175/1144 (15%)

Query: 499  PPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLSG 558
            P       G  G++G RG PG  G+PGLPG PGP+GP G  G      +PG  G +G+ G
Sbjct: 34   PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRG 93

Query: 559  LMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQG 618
              G PG  G  GL G PG  G PG QGIPG  G  G  G+PG  G  G +G PGP G  G
Sbjct: 94   PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPG 153

Query: 619  FIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPG 678
              G PG        G +G PG  G  G    QG PG  G  GP G  G PGL+G  GPPG
Sbjct: 154  MKGEPGSIIMSSLPGPKGNPGYPGPPGI---QGLPGPTGIPGPIGPPGPPGLMGPPGPPG 210

Query: 679  FPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPG----------IKGDKGEQGTAGELGEP 728
             PG +G++G +   GP G  G  GL G  G PG          ++  KG+QG  G+ G P
Sbjct: 211  LPGPKGNMG-LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPP 269

Query: 729  GYPGDKGAVGLP-GPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGP 787
            G PG +G  G P G  G +G+ G  G+ G PG  G +G PG  G PGD G PG+ G +G 
Sbjct: 270  GPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGE 329

Query: 788  KGLLGNRGPPGPP-------------------GLKGTQGEEGPIGAFGELGPRGKPGQKG 828
            KG  G+ GPPGPP                   GL G  GE+G  G  G  GP G PG  G
Sbjct: 330  KGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG 389

Query: 829  YA--GEPGPEGLKGEVGDQGNIGKIGET--GPVGLPGEVGMTGSIGEKG----------- 873
             A  G PGP G  GE G +G+ G  G +  GP GL G+ G  G  G  G           
Sbjct: 390  AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449

Query: 874  --ERGSPGPLGPQGEKGVM-------------------------GYPGPPGVPGPIGPLG 906
              E G PGP G  G+KG+                          G PG PG+PGP G LG
Sbjct: 450  ICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLG 509

Query: 907  LPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQG----------IQGAKGEKGDQGKRGPH 956
             PG  G +G  G+ GPKG  G  G  G  G  G            G KG+KG+ G  G  
Sbjct: 510  FPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAP 569

Query: 957  GLIGKTGNPGERGFQGKPGLQGLPGS---TGDRGLPGEPGLRGLQGDVGPPGEMGMEGPP 1013
            GL G  G PG+ G  G PG +G PG     G+RG PG PGL GL G++GP G  G  GPP
Sbjct: 570  GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPP 628

Query: 1014 GTEGESGLQGE---------PGAKGDVGTA----------GSVGGTGEPGLRGEPGAPGE 1054
            G  GE G+QG          PG KGD G            G+ G  G+ GL G+PG PG+
Sbjct: 629  GPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQ 688

Query: 1055 EGLQGKDGLKGVPG--GRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQR 1112
             GL G  G KG PG  G GLPG  G KG  G+PG  G  G  G+ GL GP G  G PG +
Sbjct: 689  PGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPK 748

Query: 1113 GR-----------PGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMG 1161
            G            PG  G KG +GP G+ G  GPPG  G++G  G  G +G VG  G  G
Sbjct: 749  GEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPG 808

Query: 1162 PDGEPGIPGYRGHQGQPGPSGLPGP---------KGEKGYPGEDS-TVLGPPGPRGEPGP 1211
            P G PG+PG  G QG PGP G+PGP          GEKG PG     V GPPG RG PG 
Sbjct: 809  PMGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGI 867

Query: 1212 VGDQGERGEPGAEGYKGHVGV---PGLRGATGQQGPPGEPGD------------------ 1250
             G  G  G PG+ G  G  G    PG +G  G  GPPG PG                   
Sbjct: 868  PGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGL 927

Query: 1251 QGEQGLKGERGSEGNKGKKGAPGP--------------SGKPGIPGLQGLLGPKGIQGY- 1295
            QG+ GL G  G +G+KG+ G PGP               G+PG+PG+ G+ GPKG QG  
Sbjct: 928  QGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLP 987

Query: 1296 --HGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPK 1353
               G  G+SG PG  GPPG +G PG+   PG+ GL G PG  G  G  G PG  G++GP 
Sbjct: 988  GDPGQPGLSGQPGLPGPPGPKGNPGL---PGQPGLIGPPGLKGTIGDMGFPGPQGVEGPP 1044

Query: 1354 GEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDA 1413
            G  G+PGQPG  G  G +G +GD G     GL G PG  G  GL G+ G PG KG  GD 
Sbjct: 1045 GPSGVPGQPGSPGLPGQKGDKGDPG-ISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP 1103

Query: 1414 GIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPP 1473
            G+ G+ G  G  G  G  G  G  G  GP G +GP G  G  GE GP G  G PG PGPP
Sbjct: 1104 GLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPP 1163

Query: 1474 GAPG 1477
            G  G
Sbjct: 1164 GEKG 1167



 Score =  785 bits (2027), Expect = 0.0
 Identities = 513/1256 (40%), Positives = 593/1256 (47%), Gaps = 266/1256 (21%)

Query: 487  LRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFS--PG 544
            ++G KG+ G PG  G  G+PG  G  GP G  G  G+ G+PG PGPKG +G PG    PG
Sbjct: 43   IKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPG 102

Query: 545  QP-VPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQG------------------ 585
             P +PG  G  G  G  G PG  G KG +G PG PG PG QG                  
Sbjct: 103  TPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSII 162

Query: 586  ---IPGFAGNIGSPGYPGRQGLAGPEGNPGP----------------------------- 613
               +PG  GN G PG PG QGL GP G PGP                             
Sbjct: 163  MSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNF 222

Query: 614  ------KGAQGFIGSPGEAGQLGPE----------GERGIPGIR---------------- 641
                  KG QG  G PG  GQ+  +          G++G+PG R                
Sbjct: 223  QGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG 282

Query: 642  GKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPM 701
            G+KG KG QG PG  G  G  G +G PG+ G  G PG+PG  G  G  G  G  G PGP 
Sbjct: 283  GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPP 342

Query: 702  GL-------------SGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGA--VGLPGPPGMR 746
            GL              GN GLPG+ G+KGE+G  G  G PG PG  GA  +G PGPPG  
Sbjct: 343  GLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFP 402

Query: 747  GKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPK-------GLLGNRGPPGP 799
            G+ G  G  G PG+  P GPPG +G PG  G+PG  GP GP           G  GPPG 
Sbjct: 403  GERGQKGDEGPPGISIP-GPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGS 461

Query: 800  PGLKGTQGEEGPIGAFGE-------LGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIG 852
            PG KG QGE+G  G  G+        G  G PGQ G  G PGP G  G  G +G  G+ G
Sbjct: 462  PGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAG 521

Query: 853  ETGPVGLPGEVGMTGSIGEKGERGSPGPL----GPQGEKGVMGYPGPP------------ 896
             TGP GLPG  G  G+ G  G +G PG +    G +G+KG +G PG P            
Sbjct: 522  ATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQD 581

Query: 897  GVPGPIGPLGLPGHV---GARGPPGSQGPKGQRGS--------RGPDGLLGEQGIQGAKG 945
            G+PG  GP G PG +   G RGPPG+ G  G  G+         GP G +GE+GIQG  G
Sbjct: 582  GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAG 641

Query: 946  EKGDQGKRGPHGLIGKT-GNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPP 1004
              G  G  GP G  G+T   PG+ G  G PG  G  G  GD GLPG+PGL G+ G  G P
Sbjct: 642  NPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEP 701

Query: 1005 G--EMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGE--------PGAPGE 1054
            G   +G+ GPPG +G  G+ G PGA G  G  G  G  G PG  G         PG PG 
Sbjct: 702  GIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGP 761

Query: 1055 EGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGP------------ 1102
             GL G  G  G  G RG PG  G  G  GL G+ GP G  G  G PGP            
Sbjct: 762  PGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQ 821

Query: 1103 --------EGIVGIPGQRGRPGKKGDKGQ-----IGPTGEVGSR---------GPPGKIG 1140
                     G +G PG  G PG+KGD G       GP GE GS          GPPG  G
Sbjct: 822  GPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881

Query: 1141 KSGPKGARGTRGAVGHLGLMGPDGEP---------GIPGYRGHQGQPGPSGLPGPKGEKG 1191
              G  GA G  G  G +G+MGP G P         G+PG +G  G  G  GLPGP GEKG
Sbjct: 882  LPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKG 941

Query: 1192 YPGE----------DSTVLGPPGPRGEP---------GPVGDQGERGEPGAEGYKGHVGV 1232
              GE          D  +LG  G +GEP         GP G QG  G+PG  G  G  G+
Sbjct: 942  SKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL 1001

Query: 1233 PGLRGATGQQGPPGEPGDQGEQGLK---GERGSEGNKGKKGAPGPSGKPGIP-------- 1281
            PG  G  G  G PG+PG  G  GLK   G+ G  G +G +G PGPSG PG P        
Sbjct: 1002 PGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQ 1061

Query: 1282 ------------GLQGLLGPK---GIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRT 1326
                        GL GL GPK   G+ GY G  GI G+ G  G PG  G PG +G PG  
Sbjct: 1062 KGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLP 1121

Query: 1327 GLAGAPGPPGVKGSSGLPGSPGI---------------QGPKGEQGLPGQPGIQGKRGHR 1371
            G  G PGPPG KG SG PG+PG+                GP GE+G PGQ GI G  G +
Sbjct: 1122 GFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQK 1181

Query: 1372 GAQ-----GDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIG 1426
            G       G+ GP G PGL GQ G+ G+ G+ G  G PGPKG  G  G  G+ GP GP G
Sbjct: 1182 GEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPG 1241

Query: 1427 HRGNT--GPLGREGIIGPTGR---TGPRGEKGFRGETGPQGPRGQPGPPGPPGAPG 1477
              G    GP G  G  GP GR    GP G  G  G  G +G +G PG PG PG PG
Sbjct: 1242 SPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPG 1297



 Score =  733 bits (1892), Expect = 0.0
 Identities = 458/1069 (42%), Positives = 542/1069 (50%), Gaps = 160/1069 (14%)

Query: 548  PGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGP 607
            PG K D   SG+ G  G +G  GL+GHPGLPG PG +G PG  G  G  G PG  G   P
Sbjct: 34   PGSKCD--CSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPG---P 88

Query: 608  EGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGS 667
            +G  GP G  GF G+PG            +PG+ G  G  G QG PG  G +G  G  GS
Sbjct: 89   KGIRGPPGLPGFPGTPG------------LPGMPGHDGAPGPQGIPGCNGTKGERGFPGS 136

Query: 668  PGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGE 727
            PG  G  GPPG PG+ G  G  G I  + +PGP G  G  G PGI+G  G  G  G +G 
Sbjct: 137  PGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGP 196

Query: 728  PGYPGDKGAVGLPGPPGMRGK-----SGPSGQTGDPGLQGPSGPPGP----------EGF 772
            PG PG  G  G PG PG +G       GP G+ G+ GLQGP GPPG           E  
Sbjct: 197  PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQ 256

Query: 773  PGDIGIPGQNGPEGPKGLLGNRGPPGPPG-LKGTQGEEGPIGAFGELGPRGKPGQKGYAG 831
             GD G+PG  GP GP G+   RGPPGPPG  KG +GE+G  G  G+ G  G+ GQ G  G
Sbjct: 257  KGDQGLPGDRGPPGPPGI---RGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPG 313

Query: 832  EPGPEGLKGEVGDQGNIGKIGETGPVGLPGEV----GMTGSIGEKGERGSPGPLGPQGEK 887
             PG  G  GE G  G  G+ G+TGP G PG V    G   +IGEKG  G PG  G +GE+
Sbjct: 314  LPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGER 373

Query: 888  GVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLL-----GEQGIQG 942
            G  G  GPPG+PGP G   +    G  GPPG  G +GQ+G  GP G+      G  G  G
Sbjct: 374  GFPGIQGPPGLPGPPGAAVM----GPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPG 429

Query: 943  AKGEKGDQGKRGPH----------GLIGKTGNPGERGFQGK------------------- 973
            A G  G  G  GPH          G  G  G+PG++G QG+                   
Sbjct: 430  APGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGI 489

Query: 974  ------PGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGA 1027
                  PGL GLPG  G  G PG+ G +G  G  GP G  G+ G PG  G  G +GEPG 
Sbjct: 490  SGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGD 549

Query: 1028 ----KGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMG 1083
                 G  G  G +G  G PGL G PG PG++GL G  G KG PGG    GE G  G  G
Sbjct: 550  ILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPG 609

Query: 1084 LPGIIGPLGRSGQTGL--PGP------EGIVGIPGQRGRPGKKGDKGQI----------- 1124
            LPG+ G +G  G  G   PGP      +G+ G PGQ G PG KGD GQ            
Sbjct: 610  LPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669

Query: 1125 --GPTGEVGSRGPPGKIGKSGPKGARGTRGAVG--------------HLGLMGPDGEPGI 1168
              G  G+VG  G PG  G+ G  G  G++G  G                G+ GP G PG 
Sbjct: 670  NPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGT 729

Query: 1169 PGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPG---PVGDQGERGEPGAEG 1225
            PG  G +G PGP G PGPKGE G+      + GPPGP G PG    +G +G+RG PG  G
Sbjct: 730  PGRIGLEGPPGPPGFPGPKGEPGF-----ALPGPPGPPGLPGFKGALGPKGDRGFPGPPG 784

Query: 1226 YKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPG---IPG 1282
              G  G+ GL G  G  GP G+PG  G  GL G  G +G  G  G PGP G+PG   IPG
Sbjct: 785  PPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPG 843

Query: 1283 LQGLLGPKGIQ-----GYHGADGISGNPGKIGPPGKQGLPGIRGG---PGRTGLAGAPGP 1334
             +G  GP G+      G  G+ GI G PG IGPPG  GLPG  G    PG  G  G  GP
Sbjct: 844  EKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP 903

Query: 1335 PGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCG-----DPGLKGQP 1389
            PG  G  G+PG  G+ G KG+ GL GQPG+ G  G +G++G+ G  G     DP L G  
Sbjct: 904  PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSK 963

Query: 1390 GEYGVQGLTGFQGFPGPKGPEG---DAGIVGISGPKG---PIGHRGNTGPLGREGIIGPT 1443
            GE G  GL G  G  GPKG +G   D G  G+SG  G   P G +GN G  G+ G+IGP 
Sbjct: 964  GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPP 1023

Query: 1444 GRTGPRGEKGFRGETGPQGPRG------QPGPPGPPGAPGPRKQMDINA 1486
            G  G  G+ GF G  G +GP G      QPG PG PG  G +    I++
Sbjct: 1024 GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISS 1072



 Score =  708 bits (1827), Expect = 0.0
 Identities = 425/924 (45%), Positives = 487/924 (52%), Gaps = 61/924 (6%)

Query: 477  DLNTMLEMEYLRGPKGDTGPPGPPGPAGIPGPS---GKRGPRGIP---------GPHGNP 524
            D+ T   M+  +G  G  G PG PG  G PG     G  GP+G P         GP GNP
Sbjct: 549  DILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNP 608

Query: 525  GLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKG----HPGLPGL 580
            GLPGLPG  GP G PGF P  PV GEKG QG++G  G PG+ G KG  G     PG PGL
Sbjct: 609  GLPGLPGNIGPMGPPGFGPPGPV-GEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGL 667

Query: 581  PGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGI 640
            PG  G  G  G  G PG PG+ GL G  G+ G  G  G IG PG     GP+G  GIPG 
Sbjct: 668  PGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPG-IGLPGPP---GPKGFPGIPGP 723

Query: 641  RGKKGFKGRQGFPGDFGDRGPAGLDGSPG--LVGGTGPPGFPGLRGSVGPVGPIGPAGIP 698
             G  G  GR G  G  G  G  G  G PG  L G  GPPG PG +G++GP G  G  G P
Sbjct: 724  PGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPP 783

Query: 699  GPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDP 758
            GP G +G  GLPG KGD G  G  G +G PG PG  G  G PGPPG+ G  G  G  G P
Sbjct: 784  GPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG-IGVQGPPGPPGIPGPIGQPGLHGIP 842

Query: 759  GLQGPSGP-----PGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIG 813
            G +G  GP     PGP G  G  GIPG  GP GP G  G  G  G  G  GT+GE G +G
Sbjct: 843  GEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMG 902

Query: 814  AFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVG-----MTGS 868
              G  GP G PG+ G  G  G +GL+G+ G  G  G+ G  G  GLPG  G     + GS
Sbjct: 903  PPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGS 962

Query: 869  IGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGS 928
             GEKGE G PG  G  G KG  G PG PG PG  G  GLPG  G +G PG  G  G  G 
Sbjct: 963  KGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGP 1022

Query: 929  RGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKP-----GLQGLPGST 983
             G  G +G+ G  G +G +G  G  G  G  G  G PG++G +G P     GL GLPG  
Sbjct: 1023 PGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPK 1082

Query: 984  GDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEP 1043
            G+ GLPG PG  G++G VG PG  G+ G PG +G+ GL G PG  G  G  G  G  G P
Sbjct: 1083 GEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNP 1142

Query: 1044 GLRGEP---GAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLP 1100
            GL GEP   G  G  G  G  G KG PG  G+PG  G+KGE G PG   P G  G  GL 
Sbjct: 1143 GLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNP-GPPGLPGLS 1201

Query: 1101 GPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLM 1160
            G +G  G+PG  G PG  G KG+ G  G  G +GPPG  G  GP       G  G+ G  
Sbjct: 1202 GQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP----ALEGPKGNPGPQ 1257

Query: 1161 GPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGE 1220
            GP G PG+PG  G  G PG  G+ G KG  G PG    + G PG +G+ GP G QG  G 
Sbjct: 1258 GPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPG----LPGLPGLKGDQGPPGLQGNPGR 1313

Query: 1221 PGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGK--- 1277
            PG  G KG  G+PG+ G  G +GP G PG  G +   GE G  G  G  G PGPSG+   
Sbjct: 1314 PGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPE---GEPGLIGPPGPPGLPGPSGQSII 1370

Query: 1278 ----PGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPG 1333
                 G PG+ G  G KG+ G  G  G+ G  G  G PG+ GLPG  G  GR G  G PG
Sbjct: 1371 IKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPG 1430

Query: 1334 PPGVKGSSGLPGSPGIQGPKGEQG 1357
             PG +G  G PG  G+QGP G  G
Sbjct: 1431 QPGTRGLDGPPGPDGLQGPPGPPG 1454



 Score =  451 bits (1161), Expect = e-126
 Identities = 300/737 (40%), Positives = 345/737 (46%), Gaps = 155/737 (21%)

Query: 489  GPKGDTGPPGPPGPAG------IPGPSGKRGPRGIPGPHGNPGLPGL--PGPKGPKGDPG 540
            GPKGD G PGPPGP G      +PGP G  GP G PGP G PGLPG+   GP GP G PG
Sbjct: 772  GPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPG 831

Query: 541  FSPGQP----VPGEKGDQGLSGL--MGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIG 594
               GQP    +PGEKGD G  GL   GPPG +G  G+ G PG  G PG  G+PG AG  G
Sbjct: 832  -PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASG 890

Query: 595  SPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPG 654
             PG  G  G+ GP G PGP G  G  G PG  G  G +G+ G+PG  G+KG KG  G PG
Sbjct: 891  FPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPG 950

Query: 655  DFG-----------------------------------DRGPAGLDGSPGLVGGTGPPGF 679
              G                                   D G  GL G PGL G  GP G 
Sbjct: 951  PPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN 1010

Query: 680  PGLRGSVGPVGP------IGPAGIPGPMGLSG------------NKGLPGIKGDKGEQGT 721
            PGL G  G +GP      IG  G PGP G+ G            + GLPG KGDKG+ G 
Sbjct: 1011 PGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI 1070

Query: 722  A-----------GELGEPGYPGD---KGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPP 767
            +           GE G PGYPG+   KG+VG PG PG+ G  G  GQ G PG  G  GPP
Sbjct: 1071 SSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPP 1130

Query: 768  GPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQK 827
            GP+G  G  G PG  G  GP G  G+ G PGPPG KG  G++G  G  G+   +G+PGQ 
Sbjct: 1131 GPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQ---KGEPGQP 1187

Query: 828  GYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLG----- 882
            G+ G PGP GL G  G +G+ G  G  G  GLPG  G  G  G  G +G PGP G     
Sbjct: 1188 GF-GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPA 1246

Query: 883  ---PQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGP------PGSQGPKGQRGSRGPDG 933
               P+G  G  G PG PG+PGP GP GLPG+ G +G       PG  G  G +G +GP G
Sbjct: 1247 LEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPG 1306

Query: 934  LLGEQGIQGAKGEKGDQG---------KRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTG 984
            L G  G  G  G KGD G          +GP G+ G  G  GE G  G PG  GLPG +G
Sbjct: 1307 LQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSG 1366

Query: 985  D-------------------------------------------RGLPGEPGLRGLQGDV 1001
                                                         GLPG  G  G +GD 
Sbjct: 1367 QSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDP 1426

Query: 1002 GPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKD 1061
            G PG+ G  G  G  G  GLQG PG  G    A     T        P  P +  LQ  +
Sbjct: 1427 GLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCP-QGTLQVYE 1485

Query: 1062 G--LKGVPGGRGLPGED 1076
            G  L  V G +   G+D
Sbjct: 1486 GFSLLYVQGNKRAHGQD 1502


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score =  805 bits (2079), Expect = 0.0
 Identities = 500/1163 (42%), Positives = 583/1163 (50%), Gaps = 186/1163 (15%)

Query: 489  GPKGDTGPPGPPGPAGIPGPSGK-----RGPRGIPGPHGNPGLPGLPGP----------- 532
            GP G TGPPGPPGP G PG  G+     +GP+G  G  G  G PG+PG            
Sbjct: 197  GPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFAT 256

Query: 533  ---KGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPG------E 583
               KG KG+PGF  G P  GEKG+ G  G  G PG  GDKG KG PG PG PG       
Sbjct: 257  KGEKGQKGEPGFQ-GMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGR 315

Query: 584  QGIPGFAGNIGSPGYPG---------------RQGLAGPEGNPGPKGAQGFIGSPGEAGQ 628
            QG  G  G  G PG PG                 G  GP G PGPKG  G  G PG  G 
Sbjct: 316  QGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGL 375

Query: 629  LGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSV-- 686
              P G+ G PG  G++G KG +GFPG     GP+G DG PG  G  GPPG PG    +  
Sbjct: 376  PVP-GQAGAPGFPGERGEKGDRGFPGT-SLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVE 433

Query: 687  ---GPVGPIGPAGIPGPMGLSGNKGLPGIKGDK-------------GEQGTAGELGEPGY 730
               GP G  GP GIPG  G  G  G  G KG+              G QG  GE+G PG 
Sbjct: 434  CQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQ 493

Query: 731  PGDKGAVGLPGPPGMRGKSGPSG-------------------------QTGDPGLQGPSG 765
            PG KG  GLPG  G+ G  GP G                           GDPG  G  G
Sbjct: 494  PGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPG 553

Query: 766  PPGPEGFPGDIGIPGQNGPEGPKG---LLGNRGPPGPPGLKGTQGEEGPIG--AFGELGP 820
              G  G PG  G PG  GP+G  G   L G RGPPG  G  G++G+ GP G   +G  GP
Sbjct: 554  MTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGP 613

Query: 821  RGKPGQKGYAGEPGPEGLKGEVGDQGNIGKI-GETGPVGLPGEVGMTGSIGEKGERGSPG 879
             G  GQ G+ G PG  GL G  G+ G I  + G  G  GLPG  G  G  G++G  G+PG
Sbjct: 614  IGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPG 673

Query: 880  PLGPQGEKGVMG-----YPGPPG------VPGPIGPLGLPGHVGARGPPGSQGPKGQRGS 928
              G  GEKG +G     +PGPPG      +PG +GP G PG  G  G PG+ G +GQ+G 
Sbjct: 674  RPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGE 733

Query: 929  RGPD-----GLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGST 983
             G       GL G  GI G  GEKG  G  G  G  G  G PG +G +G+PG  GLPGS 
Sbjct: 734  PGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSV 793

Query: 984  GDRGLPG--EPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQG-----EPGAKGDVGTAGS 1036
            G  G+PG   PG RG  G  GPPG   + GPPG +GE G  G      PG KGD G  G 
Sbjct: 794  GSPGVPGIGPPGARGPPGGQGPPG---LSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGL 850

Query: 1037 VGGTGE------------PGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGL 1084
             G TG+            PG+ G PG+ GE G+ G  G  G PG  G PG  GEKG+ G 
Sbjct: 851  PGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGF 910

Query: 1085 PGIIGPLGRSGQTGLPGPEGIVGIPGQ------------RGRPGKKGDKGQIGPTGEVGS 1132
            PG  GP    G  GL G +G VG+PG+            +G+ G +G+KGQIGP GE GS
Sbjct: 911  PGSSGP---RGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGS 967

Query: 1133 RGPPG------------KIGKSGPKGARGTRGAVGHLGLMGPDGE------PGIPGYRGH 1174
            RG PG            + G+ GPKG  G  G  G  GL GP G       PG PG +G 
Sbjct: 968  RGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGV 1027

Query: 1175 QGQPGPSGLPGPKGEKGYPGEDSTV----LGPPGPRGEPGPVGDQGERGEPGAEGYKGHV 1230
             G PGP G PG  G+KG  GE        +G PG RGE G  G  G  G PG +G KG +
Sbjct: 1028 PGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSI 1087

Query: 1231 GVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPK 1290
            G+PG+ G+ G +G PG  G  G  GL GE+G +G  G  G PG  G+ G+PG  G  GP 
Sbjct: 1088 GIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPA 1147

Query: 1291 GIQGYHGADGISGNPGKIGPPGK--QGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPG 1348
            G +G  G+DGI G+ G+ G PG   +G PG  G  G  G  G  G PG+ GS G+PGS G
Sbjct: 1148 GQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKG 1207

Query: 1349 IQGPKGEQGLPGQPGIQGKRGH--RGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQ----- 1401
             QG  G  G  GQPG+ G  GH   G +GD+GP G PGL G PG  G  GL G       
Sbjct: 1208 EQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGD 1267

Query: 1402 ----------GFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGE 1451
                      G PGPKG  G  G+ GI G  G  G +G+ GP G  G  GP G  G +G 
Sbjct: 1268 KGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGI 1327

Query: 1452 KGFRGETGPQGPRGQPGPPGPPG 1474
            KG +G+ G  G +G PGPPGPPG
Sbjct: 1328 KGDQGDQGVPGAKGLPGPPGPPG 1350



 Score =  802 bits (2071), Expect = 0.0
 Identities = 496/1171 (42%), Positives = 604/1171 (51%), Gaps = 198/1171 (16%)

Query: 492  GDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVP--- 548
            G+ G PG PGP G PG  G +G +G PG  G PG PGL G +GP+G+ G   G P P   
Sbjct: 275  GEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKG-EAGPPGPPGI 333

Query: 549  -------GEKGDQGLSGLMGP---PGMQGDKGLKGHPGLPGLP--GEQGIPGFAGNIGS- 595
                   GEKG++G  G  GP   PG +G  GL G PG PGLP  G+ G PGF G  G  
Sbjct: 334  VIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEK 393

Query: 596  ----------PGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKG 645
                      PG  GR GL GP G+PGP G  G+     E  Q GP G++G PGI G+ G
Sbjct: 394  GDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVEC-QPGPPGDQGPPGIPGQPG 452

Query: 646  FKGRQGFPGDFGD----------RGPAGLDGSPGLVGGTGPPGFPG---LRGSVGPVGPI 692
            F G  G  G  G+          RGP G  G PG +G  G PG  G   L G  G  G  
Sbjct: 453  FIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVP 512

Query: 693  GPAGIPGPMGLSGNKGLPG-------IKGDKGEQG---------TAGELGEPGYPGDKGA 736
            GP G PG +G  G KG PG       +KGDKG+ G          AG  G  G+PG  G 
Sbjct: 513  GPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGP 572

Query: 737  VGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEG--------------FPGDIGIPGQN 782
             G PG  G++G+ GP G  G PG +G +GPPGP G              FPG  G PG  
Sbjct: 573  KGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLP 632

Query: 783  GPEGPKGLL----------------------GNRGPPGPPGLKGTQGEEGPIGAFG---- 816
            GP+G  G +                      G+RG PG PG  G  GE+G +G  G    
Sbjct: 633  GPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFP 692

Query: 817  -------------ELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEV 863
                         ++GP G PG+ G+ G PG  G++G+ G+ G    +G  G  GLPG  
Sbjct: 693  GPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPG----VGLPGLKGLPGLP 748

Query: 864  GMTGSIGEKGERGSPG------PLGPQGEKGVMGYPGPPGVPGPIGPLGLPG--HVGARG 915
            G+ G+ GEKG  G PG       +GP G +G+ G PGPPG+PG +G  G+PG    GARG
Sbjct: 749  GIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARG 808

Query: 916  PPGSQGPKGQRGSRGPDGLLGEQGIQG-----AKGEKGDQGKRGPHGLIGKTGNPGERGF 970
            PPG QGP G  G   P G+ GE+G  G       G KGD+G +G  G+ G++G PG  G 
Sbjct: 809  PPGGQGPPGLSG---PPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQ 865

Query: 971  QGKPGLQGLPGSTGDRGL---PGEPG---------LRGLQGDVGPPGEMGMEGPPGTEGE 1018
            QG PG+ G PGS G+ G+   PG+PG         L G +GD G PG  G  G PG +G+
Sbjct: 866  QGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGD 925

Query: 1019 SG---LQGEPGA------------KGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGL 1063
             G   L G+PG+            KGD G  G +G  GE G RG+PG PG  G  G+ G 
Sbjct: 926  KGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQ 985

Query: 1064 KGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQ 1123
             G PG +G PG  G  G  GLPG  G +G  G  G PG +G+ GIPG +G PG  GDKG 
Sbjct: 986  PGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGA 1045

Query: 1124 IGPTGEVGS--------RGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQ 1175
             G  G+ G         RG  G  G +G  G+ G +G  G +G+ G  G PG+ G  G  
Sbjct: 1046 KGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSV 1105

Query: 1176 GQPGPSGLPGPKGEKGYPGEDST--VLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVP 1233
            G PG  GLPG KG+KG PG D    V G  G  G PGP G  G++GEPG++G  G  G  
Sbjct: 1106 GYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEK 1165

Query: 1234 GLRGATGQQGPPGEPGDQGEQGLKGE------------RGSEGNKGKKGAPGPSGKPGIP 1281
            G  G  G+ G PG PG +G++G KGE             GS+G +G  G PGP G+PG+P
Sbjct: 1166 GEPGLPGR-GFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLP 1224

Query: 1282 GLQGLL--GPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKG 1339
            G  G    GPKG +G  G  G+ G PG +GPPG  G+ G++G  G  G  GAPG PG KG
Sbjct: 1225 GSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKG 1284

Query: 1340 SSG------LPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQG---DQGPCGDPGLKGQPG 1390
              G      + GSPGI G KG+ G PG PG QG +G  G QG   DQG  G PG KG PG
Sbjct: 1285 DPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPG 1344

Query: 1391 EYGVQG----LTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRT 1446
              G  G    + G  G PGP+GP G  G+ G+ GPKG    +G TG +G  G  G  G  
Sbjct: 1345 PPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKG---QQGVTGLVGIPGPPGIPGFD 1401

Query: 1447 GPRGEKGFRGETGPQGPRGQPGPPGPPGAPG 1477
            G  G+KG  G  GP GPRG PGPPGP G PG
Sbjct: 1402 GAPGQKGEMGPAGPTGPRGFPGPPGPDGLPG 1432



 Score =  790 bits (2039), Expect = 0.0
 Identities = 504/1166 (43%), Positives = 587/1166 (50%), Gaps = 185/1166 (15%)

Query: 488  RGPKGDTGPPGPPGPAGIPGPSGK-------------------RGPRGIPGPHGNPGLPG 528
            +G +G  GPPG PG AG PGP G                    +G RG PG  G PG PG
Sbjct: 129  KGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPG 188

Query: 529  LPGPKGPKGDPGFS-----PGQP-VPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGL-- 580
            LPG +GP G PGF+     PG P  PGEKG  GLS   GP G +GD+G+ G PG+PG   
Sbjct: 189  LPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLS-FQGPKGDKGDQGVSGPPGVPGQAQ 247

Query: 581  ------------------PGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGS 622
                              PG QG+PG  G  G PG PG +G  G +G+ G KG+ GF G 
Sbjct: 248  VQEKGDFATKGEKGQKGEPGFQGMPG-VGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGE 306

Query: 623  PGEAGQLG---PEGERGI------PGI---RGKKGFKGRQGFPGDFGDRGPAGLDGSPGL 670
            PG  G +G   P+GE+G       PGI    G  G KG +G+PG  G RG  G  G PGL
Sbjct: 307  PGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGL 366

Query: 671  VGGTGPPG-----------FPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQ 719
             G  GPPG           FPG RG  G  G  G + +PGP G  G  G PG  G  G+ 
Sbjct: 367  PGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTS-LPGPSGRDGLPGPPGSPGPPGQP 425

Query: 720  GTAGELGE--PGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGL----QGPSGPPGPEGFP 773
            G    + E  PG PGD+G  G+PG PG  G+ G  GQ G+  L     G  GPPGP+G P
Sbjct: 426  GYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPP 485

Query: 774  GDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGP------------- 820
            G+IG PGQ G +G +GL G  G  G PG +GT G  G  GA GE G              
Sbjct: 486  GEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGD 545

Query: 821  ---RGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGS 877
                G+PG  G AG PG +G  G  G +G+ G +G  G  G PG VG  GS G+ G  G 
Sbjct: 546  PGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGP 605

Query: 878  PG--PLGPQGEKGVMGYPGPPGVPGPIGPLG-------LPGHVGARGPPGSQGPKGQRGS 928
            PG  P GP G+KG  G+PG PG PG  GP G       LPG  GA G PGS G  G +G 
Sbjct: 606  PGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGD 665

Query: 929  RGPDGLLGEQGIQGAKGEKGDQG-----KRGPHGLIGKTGNPGERGFQGKPGLQGLPGST 983
            RG  G  G  G+ G KG  G  G       GP G+ G  G+ G  G  G+PG  GLPG+ 
Sbjct: 666  RGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNP 725

Query: 984  GDRGLPGEPG--------LRGLQGDVGPPGEMGMEGPPGTEGE---------SGLQGEPG 1026
            G +G  GEPG        L GL G  G PGE G  G PG  GE          G++GEPG
Sbjct: 726  GVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPG 785

Query: 1027 AKGDVGTAGSVG--GTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGED-----GEK 1079
              G  G+ GS G  G G PG RG PG  G  GL G  G+KG  G  G PG D     G+K
Sbjct: 786  PPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDK 845

Query: 1080 GEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKI 1139
            G  GLPGI G  G  G  G  G  GI G PG +G  G  G  GQ G  G VG+ G PG+ 
Sbjct: 846  GAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEK 905

Query: 1140 GKSGPKGARGTRGAVGHLGLMGPDGEPGIPG---------YRGHQGQPGPSGLPGPKGEK 1190
            G  G  G+ G RG  G  G  G  G PG PG          +G +G  G  G  GP GEK
Sbjct: 906  GDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEK 965

Query: 1191 GYPGEDSTVL-----GPPGPRGEPGPVGDQGERGEPGAEGY---KGHVGVPGLRGATGQQ 1242
            G  G+  T       G  G  G+PGP GD G  G PGA G    KG VG  GL G  G++
Sbjct: 966  GSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEK 1025

Query: 1243 GPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGIS 1302
            G PG PG QG  GL G++G++G KG+ G PG     GIPGL+G  G +GI G+ G+ G  
Sbjct: 1026 GVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGI----GIPGLRGEKGDQGIAGFPGSPGEK 1081

Query: 1303 GNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQP 1362
            G  G IG PG  G PG++G PG  G  G+PG PG KG  GLPG  GI G KGE GLPG P
Sbjct: 1082 GEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTP 1141

Query: 1363 GIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGD---------A 1413
            G  G  G +G  G  G  G  G KG+PG  G     GF GFPG KG +G          A
Sbjct: 1142 GPTGPAGQKGEPGSDGIPGSAGEKGEPGLPG----RGFPGFPGAKGDKGSKGEVGFPGLA 1197

Query: 1414 GIVGISGPKGPIGHRGNTGPLGREGI--------IGPTGRTGPRGEKGFRGETGPQGP-- 1463
            G  GI G KG  G  G  GP G+ G+         GP G  GP+G+ G  G  GP GP  
Sbjct: 1198 GSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPG 1257

Query: 1464 ----------RGQPGPPGPPGAPGPR 1479
                      +G PG PG PG PGP+
Sbjct: 1258 LPGIDGVKGDKGNPGWPGAPGVPGPK 1283



 Score =  740 bits (1911), Expect = 0.0
 Identities = 463/1061 (43%), Positives = 544/1061 (51%), Gaps = 116/1061 (10%)

Query: 501  GPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLSGLM 560
            G     G  G++G RG+PG  G  G PG+ GP+GP+G          PG+KGD G  GL 
Sbjct: 37   GKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGP---------PGQKGDTGEPGLP 87

Query: 561  GPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFI 620
            G  G +G  G  G+PG PGLP   GIPG  G  G PG PG  G  G  G  GP G  GF 
Sbjct: 88   GTKGTRGPPGASGYPGNPGLP---GIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFA 144

Query: 621  GSPGEAGQLGPEGERG-----IPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTG 675
            G+PG  G  G +G+ G     +PG+      KG +GFPG  G  GP GL   PGL G  G
Sbjct: 145  GNPGPPGLPGMKGDPGEILGHVPGML----LKGERGFPGIPGTPGPPGL---PGLQGPVG 197

Query: 676  PPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGY----- 730
            PPGF    G  GP GP GP G  G MGLS      G KGDKG+QG +G  G PG      
Sbjct: 198  PPGF---TGPPGPPGPPGPPGEKGQMGLS----FQGPKGDKGDQGVSGPPGVPGQAQVQE 250

Query: 731  ------PGDKGAVGLPGPPGM-----RGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIP 779
                   G+KG  G PG  GM     +G+ G  G  G PG  G  G  G  GFPG+ G P
Sbjct: 251  KGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYP 310

Query: 780  GQNGPEGPKGLLGNRGPPGPPGL---KGTQGEEGPIGAFGELGPRGKPGQKGY---AGEP 833
            G  G +GP+G  G  GPPGPPG+    G  GE+G  G  G  GPRG+PG KG+    G+P
Sbjct: 311  GLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQP 370

Query: 834  GPEGL--KGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKG--- 888
            GP GL   G+ G  G  G+ GE G  G PG   + G  G  G  G PG  GP G+ G   
Sbjct: 371  GPPGLPVPGQAGAPGFPGERGEKGDRGFPG-TSLPGPSGRDGLPGPPGSPGPPGQPGYTN 429

Query: 889  --VMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPK-------GQRGSRGPDGLLGEQG 939
              V   PGPPG  GP G  G PG +G  G  G +G         G RG  GP G  GE G
Sbjct: 430  GIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIG 489

Query: 940  IQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLP----------GSTGDRGLP 989
              G  G KGD+G  G  G+ G  G  G  G  G+PG +G P          G  GD G P
Sbjct: 490  FPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFP 549

Query: 990  GEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEP 1049
            G+PG+ G  G  G  G  G+ GP G+ G  GL+GE G  G VG  GS G TG PG  G  
Sbjct: 550  GQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGY- 608

Query: 1050 GAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGE-MGLPGIIGPLGRSGQTGLPGPEGIVGI 1108
            G  G  G +G+ G  G PG  GLPG  GE G+ + LPG  G  G  G  G PGP+G  G 
Sbjct: 609  GPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGF 668

Query: 1109 PGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGI 1168
            PG  GRPG  G+KG +G  G +G  GPPG  G  G  G  G  G  G  G  G  G PG+
Sbjct: 669  PGTPGRPGLPGEKGAVGQPG-IGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGV 727

Query: 1169 PGYRGHQ--GQPGPSGLPGPKGEKGYPGEDST--VLGPPGPRGEPGPVGDQGERGEPGAE 1224
             G +G    G PG  GLPG  G  G PGE  +  V G PG  G  GP G QG RGEPG  
Sbjct: 728  QGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPP 787

Query: 1225 GYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKG-----APGPSGKPG 1279
            G  G VG PG+ G  G  G  G PG QG  GL G  G +G KG  G      PGP G  G
Sbjct: 788  GLPGSVGSPGVPG-IGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKG 846

Query: 1280 IPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKG 1339
              GL G+ G  G+ G  G  G  G PG  G  G+ G+ G  G PG  G  GAPG PG KG
Sbjct: 847  AQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKG 906

Query: 1340 SSGLPGS------PGIQGPKGEQGLPGQPG---------IQGKRGHRGAQGDQGPCGDPG 1384
              G PGS      PG++G KG+ GLPG+PG         ++G++G +G +G  GP G+ G
Sbjct: 907  DHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKG 966

Query: 1385 LKGQPGEYGVQGLTGFQGFPGPKGPEGDAGI------VGISGPKGPIGHRGNTGPLGREG 1438
             +G PG  GV G  G  G PG  GP+GD GI       G+ GPKG +G  G  G  G +G
Sbjct: 967  SRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKG 1026

Query: 1439 IIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPR 1479
            +    G  GP+G  G  G+ G +G +GQ GPPG  G PG R
Sbjct: 1027 V---PGIPGPQGSPGLPGDKGAKGEKGQAGPPG-IGIPGLR 1063



 Score =  707 bits (1824), Expect = 0.0
 Identities = 450/1060 (42%), Positives = 533/1060 (50%), Gaps = 170/1060 (16%)

Query: 489  GPKGDTGPPGPPGPAGIPGPSGKRGP-------------RGIPGPHGNPGLPGLPGPKGP 535
            GP GD GPPG PG  G  G  G++G              RG PGP G PG  G PG  G 
Sbjct: 437  GPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGA 496

Query: 536  KGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKG-------LKGHPGLPGLPGEQGIPG 588
            KGD G      V G  G QG  GL+G PG +G+ G       LKG  G PG PG+   PG
Sbjct: 497  KGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQ---PG 553

Query: 589  FAGNIGSPGYPGRQGLAGPEGNPG---------PKGAQGFIGSPGEAGQLGPEG--ERGI 637
              G  GSPG  G  GL GP+G+PG         P G  GF GS G+ G  GP G    G 
Sbjct: 554  MTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGP 613

Query: 638  PGIRGKKGFKGRQGFPGDFGDRGPAG----LDGSPGLVGGTGPPGFPGLRGSVGPVGPIG 693
             G +G+ GF G  G PG  G +G  G    L G PG  G  G PGFPG +G  G  G  G
Sbjct: 614  IGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPG 673

Query: 694  PAGIPGPMGLSGNKGL--PGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGP 751
              G+PG  G  G  G+  PG  G KG  G  G++G PG PG  G  GLPG PG++G+ G 
Sbjct: 674  RPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGE 733

Query: 752  SGQTGDPGLQGPSGPPGPEGFPGDIG------IPGQNGPEGPKGLLGNRGPPGPPGLKGT 805
             G  G PGL+G  G PG  G PG+ G      +PG++G  GP GL G RG PGPPGL G+
Sbjct: 734  PG-VGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGS 792

Query: 806  QGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQG-----NIGKIGETGPVGLP 860
             G  G  G  G  G RG PG +G  G  GP G+KGE G  G       G  G+ G  GLP
Sbjct: 793  VGSPGVPG-IGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLP 851

Query: 861  GEVGMTGSIGEKGERGSPGPLG---PQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPP 917
            G  G +G  G  G++G+PG  G    +GE GVMG PG PG PGP+G  GLPG  G  G P
Sbjct: 852  GITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFP 911

Query: 918  GSQGPKGQRGSRGPDGLLGEQGIQGA---------KGEKGDQGKRGPHGLIGKTGN---- 964
            GS GP+G  G +G  G +G  G  G+         KG+KGDQG++G  G IG+ G+    
Sbjct: 912  GSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDP 971

Query: 965  -----PGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVG------PPGEMGMEGPP 1013
                 PG+ G  G+PG  G  G  G  G PG PGL G +G VG       PGE G+ G P
Sbjct: 972  GTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIP 1031

Query: 1014 GTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGE------------------------P 1049
            G +G  GL G+ GAKG+ G AG  G  G PGLRGE                        P
Sbjct: 1032 GPQGSPGLPGDKGAKGEKGQAGPPG-IGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIP 1090

Query: 1050 GAPGEEGLQGKDGLKGVPGGRGLPGEDGEKG------------EMGLPGIIGPLGRSGQT 1097
            G PG  GL+G  G  G PG  GLPGE G+KG            E GLPG  GP G +GQ 
Sbjct: 1091 GMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQK 1150

Query: 1098 GLPGPEGIVGIPGQRGRPGK--KGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVG 1155
            G PG +GI G  G++G PG   +G  G  G  G+ GS+G  G  G +G  G  G++G  G
Sbjct: 1151 GEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQG 1210

Query: 1156 HLGLMGPDGEPGIPGYRGH-----------QGQPGPSGLPGPKGEKGYPGEDSTVLGPPG 1204
             +G  GP G+PG+PG  GH           QGQPG  GLPGP G  G PG D  V G  G
Sbjct: 1211 FMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDG-VKGDKG 1269

Query: 1205 PRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGE------QGLKG 1258
              G PG  G  G +G+PG +G  G  G PG+ G+ G  GPPG PG QG       QG+KG
Sbjct: 1270 NPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKG 1329

Query: 1259 ERGSEGNKGKKGAPGPSGKPGI-------PGLQGLLGPKGIQGYHGADGISGNPGKIGPP 1311
            ++G +G  G KG PGP G PG        PGL G  GP G++G                 
Sbjct: 1330 DQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGL---------------- 1373

Query: 1312 GKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHR 1371
              QGLPG +G  G TGL G PGPPG+ G  G PG  G  GP G  G  G P   G  G  
Sbjct: 1374 --QGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFP---GPPGPD 1428

Query: 1372 GAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEG 1411
            G  G  GP G P +     ++G       Q    P+ P G
Sbjct: 1429 GLPGSMGPPGTPSV-----DHGFLVTRHSQTIDDPQCPSG 1463



 Score =  689 bits (1778), Expect = 0.0
 Identities = 399/926 (43%), Positives = 481/926 (51%), Gaps = 85/926 (9%)

Query: 487  LRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPG---------------LPGLPG 531
            L+G KGD G PG PG  G  G  G+ G  G+PGP G+PG                PG  G
Sbjct: 539  LKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRG 598

Query: 532  PKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKG-------LKGHPGLPGLPGEQ 584
              GP G PG+ P  P+ G+KG  G  G  G PG+ G KG       L G PG  GLPG  
Sbjct: 599  DTGPPGPPGYGPAGPI-GDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSP 657

Query: 585  GIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKK 644
            G PG  G+ G PG PGR GL G +G  G  G  GF G PG  G  G  G+ G PG  G+ 
Sbjct: 658  GFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGI-GFPGPPGPKGVDGLPGDMGPPGTPGRP 716

Query: 645  GFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLS 704
            GF G  G PG  G +G  G+    GL G  G PG PG+ G+ G  G IG  G+PG  G  
Sbjct: 717  GFNGLPGNPGVQGQKGEPGV----GLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAI 772

Query: 705  GNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPS 764
            G  GL GI+G+ G  G  G +G PG PG    +G PG  G  G  GP G +G PG++G  
Sbjct: 773  GPPGLQGIRGEPGPPGLPGSVGSPGVPG----IGPPGARGPPGGQGPPGLSGPPGIKGEK 828

Query: 765  G--------PPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFG 816
            G         PGP+G  G  G+PG  G  G  GL G +G PG PG  G++GE G +G  G
Sbjct: 829  GFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPG 888

Query: 817  ELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSI------G 870
            + G  G  G  G  GE G  G  G  G +G+ G  G+ G VGLPG+ G    +      G
Sbjct: 889  QPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKG 948

Query: 871  EKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRG 930
            +KG++G  G +GP GEKG  G PG PGVPG  G  G PG  G +G PG  G  G  G  G
Sbjct: 949  QKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPG 1008

Query: 931  PDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGK--------PGLQGLPGS 982
            P G +G  G+ G  GEKG  G  GP G  G  G+ G +G +G+        PGL+G  G 
Sbjct: 1009 PKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGD 1068

Query: 983  TGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGE 1042
             G  G PG PG +G +G +G PG  G  G  G+ G  G  G PG  G+ G  G  G  G 
Sbjct: 1069 QGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGI 1128

Query: 1043 PGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPG--IIGPLGRSGQTGLP 1100
            PG++GE G PG  G  G  G KG PG  G+PG  GEKGE GLPG    G  G  G  G  
Sbjct: 1129 PGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSK 1188

Query: 1101 GPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKS--GPKGARGTRGAVGHLG 1158
            G  G  G+ G  G PG KG++G +GP G  G  G PG  G +  GPKG RG +G  G  G
Sbjct: 1189 GEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPG 1248

Query: 1159 LMGPDGEPGIPGY------RGHQGQPGPSGLPGPKGEKGYPGEDST-----VLGPPGPRG 1207
            L GP G PG+PG       +G+ G PG  G+PGPKG+ G+ G         + G  G  G
Sbjct: 1249 LPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMG 1308

Query: 1208 EPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGD----QGEQGLKGERGSE 1263
             PG  G QG +G PG +G KG  G  G+ GA G  GPPG PG     +GE GL G  G  
Sbjct: 1309 PPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPP 1368

Query: 1264 GNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGP 1323
            G KG +G PGP G+ G+ GL G+ GP GI G+ GA G  G  G  GP G +G P      
Sbjct: 1369 GLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFP------ 1422

Query: 1324 GRTGLAGAPGPPGVKGSSGLPGSPGI 1349
                  G PGP G+ GS G PG+P +
Sbjct: 1423 ------GPPGPDGLPGSMGPPGTPSV 1442



 Score =  637 bits (1643), Expect = 0.0
 Identities = 399/925 (43%), Positives = 471/925 (50%), Gaps = 96/925 (10%)

Query: 627  GQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSV 686
            G  G +GERG+PG++G  GF G QG         P G  G PG  G TG PG PG +G+ 
Sbjct: 43   GVKGQKGERGLPGLQGVIGFPGMQG---------PEGPQGPPGQKGDTGEPGLPGTKGTR 93

Query: 687  GPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMR 746
            GP G  G  G PG  G+ G  G PG  G  G  GT GE G  G PG  G  G PGPPG+ 
Sbjct: 94   GPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLP 153

Query: 747  GKSGPSGQTGD--PG--LQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGL 802
            G  G  G+     PG  L+G  G PG  G PG  G+PG  GP GP G  G  GPPGPPG 
Sbjct: 154  GMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGP 213

Query: 803  KGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGE 862
             G +G+ G        GP+G  G +G +G PG  G + +V ++G+    GE G  G PG 
Sbjct: 214  PGEKGQMG----LSFQGPKGDKGDQGVSGPPGVPG-QAQVQEKGDFATKGEKGQKGEPGF 268

Query: 863  VGMTGSIGEKGERGSPGPLGP------QGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGP 916
             GM G +GEKGE G PGP G       +GEKG  G+PG PG PG IG  G  G  G  GP
Sbjct: 269  QGMPG-VGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGP 327

Query: 917  PG------SQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGL-----IGKTGNP 965
            PG        GP G++G RG  G  G +G  G KG  G  G+ GP GL      G  G P
Sbjct: 328  PGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFP 387

Query: 966  GERGFQGKPGLQG--LPGSTGDRGLPGEPGLRGLQGDVG--------PPGEMGMEGPPGT 1015
            GERG +G  G  G  LPG +G  GLPG PG  G  G  G         PG  G +GPPG 
Sbjct: 388  GERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGI 447

Query: 1016 EGESGLQGEPGAKGDVGTA-------------GSVGGTGEPGLRGEPGAPGEEGLQGKDG 1062
             G+ G  GE G KG  G +             G  G  GE G  G+PGA G+ GL G+DG
Sbjct: 448  PGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDG 507

Query: 1063 LKGVPGGRGLPGEDGEKGEMGLPG-------IIGPLGRSGQTGLPGPEGIVGIPGQRGRP 1115
            + GVPG +G PG  G+ G  G PG       + G  G  G  G PG  G  G PG+ G P
Sbjct: 508  VAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHP 567

Query: 1116 GKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQ 1175
            G  G KG  G  G  G RGPPG +G  G +G  G  G  G+    GP G  G  G  G  
Sbjct: 568  GLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGY----GPAGPIGDKGQAGFP 623

Query: 1176 GQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGL 1235
            G PG  GLPGPKGE   PG+   + GPPG  G PG  G  G +G+ G  G  G  G+PG 
Sbjct: 624  GGPGSPGLPGPKGE---PGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGE 680

Query: 1236 RGATGQQGP--PGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQG-----LLG 1288
            +GA GQ G   PG PG +G  GL G+ G  G  G+ G  G  G PG+ G +G     L G
Sbjct: 681  KGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPG 740

Query: 1289 PKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPG 1348
             KG+ G  G  G  G  G IG PG  G  G  G PG  G+ G PGPPG+ GS G PG PG
Sbjct: 741  LKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPG 800

Query: 1349 I-----QGPKGEQGLPG---QPGIQGKRGHRGAQGDQ--GPCGDPGLKGQPGEYGVQGLT 1398
            I     +GP G QG PG    PGI+G++G  G  G    GP GD G +G PG   + G +
Sbjct: 801  IGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPG---ITGQS 857

Query: 1399 GFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGET 1458
            G  G P   G +G  GI G  G KG +G  G  G  G  G +G  G  G +G+ GF G +
Sbjct: 858  GLPGLP---GQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSS 914

Query: 1459 GPQGPRGQPGPPGPPGAPGPRKQMD 1483
            GP+G  G  G  G  G PG    MD
Sbjct: 915  GPRGDPGLKGDKGDVGLPGKPGSMD 939



 Score =  379 bits (973), Expect = e-104
 Identities = 228/515 (44%), Positives = 266/515 (51%), Gaps = 52/515 (10%)

Query: 477  DLNTMLEMEYLRGPKGDTGP------------PGPPGPAGIPGPSGKRGPRGIPGPHGNP 524
            D+ +M   +  +G KG  GP            PG PG  G  G  G+ GP+G PG  G P
Sbjct: 942  DMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTP 1001

Query: 525  GLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGH---------- 574
            G PGLPGPKG  G  G  PG   PGEKG  G+ G  G PG+ GDKG KG           
Sbjct: 1002 GAPGLPGPKGSVGGMGL-PG--TPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIG 1058

Query: 575  -PGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEG 633
             PGL G  G+QGI GF G+ G  G  G  G+ G  G+PG KG+ G +G PG  G  G +G
Sbjct: 1059 IPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKG 1118

Query: 634  ERGIPGIRGKKGFKGRQGFPGDFGDRGPA------GLDGSPGLVGGTGPPGFPGLRGSVG 687
            ++G+PG+ G  G KG  G PG  G  GPA      G DG PG  G  G PG PG RG  G
Sbjct: 1119 DKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPG-RGFPG 1177

Query: 688  PVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPP---- 743
              G  G  G  G +G  G  G PGI G KGEQG  G       PG +G  GLPG P    
Sbjct: 1178 FPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGP------PGPQGQPGLPGSPGHAT 1231

Query: 744  -GMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGL 802
             G +G  GP GQ G PGL GP GPPG  G  G  G  G  G  G  G+ G +G PG  G+
Sbjct: 1232 EGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGM 1291

Query: 803  KGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGE 862
             G  G  G  G+ G++GP G PG +G  G PG +G+KG+ GDQG  G  G  GP G PG 
Sbjct: 1292 PGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGP 1351

Query: 863  VGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGP 922
              +      KGE G PGP GP G KG+ G PGP G  G  G +G+PG  G    PG  G 
Sbjct: 1352 YDII-----KGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGI---PGFDGA 1403

Query: 923  KGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHG 957
             GQ+G  GP G  G +G  G  G  G  G  GP G
Sbjct: 1404 PGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPG 1438



 Score =  325 bits (834), Expect = 2e-88
 Identities = 222/558 (39%), Positives = 265/558 (47%), Gaps = 116/558 (20%)

Query: 1027 AKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVP------GGRGLPGEDGEKG 1080
            AKG  G AGS  G G+    G  G  GE GL G  G+ G P      G +G PG+ G+ G
Sbjct: 27   AKG--GCAGS--GCGKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTG 82

Query: 1081 EMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGK-- 1138
            E GLPG  G  G  G +G PG  G+ GIPGQ G PG  G  G  G  GE G  GPPG   
Sbjct: 83   EPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPG 142

Query: 1139 -IGKSGPKGARGTRG----AVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYP 1193
              G  GP G  G +G     +GH+  M   GE G PG     G PGP GLPG +G  G P
Sbjct: 143  FAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGI---PGTPGPPGLPGLQGPVGPP 199

Query: 1194 GEDSTVLGPPGPRGEPGPVGD--------QGERGEPGAEGYKGHVGVPG----------- 1234
            G      GPPGP G PGP G+        QG +G+ G +G  G  GVPG           
Sbjct: 200  G----FTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFA 255

Query: 1235 LRGATGQQGPP--------GEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGL 1286
             +G  GQ+G P        GE G+ G+ G +G+ G +G+KG+KG+PG  G+PG PGL G 
Sbjct: 256  TKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGR 315

Query: 1287 LGPKGIQ------------------GYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGL 1328
             GP+G +                  G  G  G  G PG  G PG +G PG+ G PG  GL
Sbjct: 316  QGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGL 375

Query: 1329 -----AGAPGPPGVKGSSGLPGSPG--IQGPKGEQGLPGQPGIQGKRG-----------H 1370
                 AGAPG PG +G  G  G PG  + GP G  GLPG PG  G  G            
Sbjct: 376  PVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQ 435

Query: 1371 RGAQGDQGPCGDPGLKGQPGEYGVQG----------LTGFQGFPGPKGPEGDAGIVGISG 1420
             G  GDQGP G PG  G  GE G +G          + G++G PGP+GP G+ G  G  G
Sbjct: 436  PGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPG 495

Query: 1421 PKGPIGHRGN------TGPLGREGIIGPTGR-------------TGPRGEKGFRGETGPQ 1461
             KG  G  G        GP G  G+IG  G               G +G+ GF G+ G  
Sbjct: 496  AKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMT 555

Query: 1462 GPRGQPGPPGPPGAPGPR 1479
            G  G PG  G PG PGP+
Sbjct: 556  GRAGSPGRDGHPGLPGPK 573



 Score =  127 bits (320), Expect = 7e-29
 Identities = 75/184 (40%), Positives = 89/184 (48%), Gaps = 28/184 (15%)

Query: 1327 GLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLK 1386
            G+ G  G  G+ G  G+ G PG+QGP+G QG PGQ G  G+ G  G +G +GP   PG  
Sbjct: 43   GVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGP---PGAS 99

Query: 1387 GQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGP---IGHRGNTGP---------- 1433
            G PG  G+ G+ G  G PGP G  G  G  G  GP GP    G  GN GP          
Sbjct: 100  GYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDP 159

Query: 1434 ------------LGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQ 1481
                         G  G  G  G  GP G  G +G  GP G  G PGPPGPPG PG + Q
Sbjct: 160  GEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQ 219

Query: 1482 MDIN 1485
            M ++
Sbjct: 220  MGLS 223



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 33/73 (45%), Positives = 36/73 (49%), Gaps = 12/73 (16%)

Query: 484  MEYLRGPKGDTG---------PPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPG---LPG 531
            ++ L GPKG  G         PPG PG  G PG  G+ GP G  GP G PG PG   LPG
Sbjct: 1373 LQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPG 1432

Query: 532  PKGPKGDPGFSPG 544
              GP G P    G
Sbjct: 1433 SMGPPGTPSVDHG 1445


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  785 bits (2028), Expect = 0.0
 Identities = 505/1237 (40%), Positives = 598/1237 (48%), Gaps = 268/1237 (21%)

Query: 489  GPKGDTGPPGPPGPAGIPGPSGKRGPRGI-----PGPHGNPG------------LPGLPG 531
            GPKG+ G  GP GP G  G  G+RGP G+     PGP G+PG             PG  G
Sbjct: 1551 GPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSG 1610

Query: 532  PKGPKGDPGFSPGQPVP----------GEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLP 581
            P G KGDPG  PG P P          GEKGD+G  G  G PG  G++GL+G PG+ G  
Sbjct: 1611 PPGEKGDPG-RPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPV 1669

Query: 582  GEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFI----------GSPGEAGQLGP 631
            GE+G  G  G  G  G PG  G  G  G PGP G  G +          G PG+ GQ GP
Sbjct: 1670 GEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGP 1729

Query: 632  EGERGIPGI------RGKKGFKGRQGFPGDFGDRGPAG---------------LDGSPGL 670
             G +G PG+      RG +GF+G  G  GD G RGPAG               LDG PG 
Sbjct: 1730 RGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGA 1789

Query: 671  VGGTGP------------PGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGE 718
             G +GP             G PGLRG  G  GP GP G+PG  G  G  GL G  G+ G+
Sbjct: 1790 AGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGD 1849

Query: 719  QGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGI 778
             G  G  GE G  G  G  G  GP G RG  G  G  G PGL GP GPPG +GFPG   +
Sbjct: 1850 PGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPG-QGFPG---V 1905

Query: 779  PGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPI-------------------------- 812
            PG  GP+G +G  G++G  G PG +G +GE G +                          
Sbjct: 1906 PGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDE 1965

Query: 813  -------------GAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGK----IGETG 855
                         G  G+ G +G PG++G  G PG  GLKG+ GD G  G     +GE G
Sbjct: 1966 SSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERG 2025

Query: 856  PVG---------------LPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPG 900
            P G               LPG  G  G  G  GERG  G  G +GE+G  G PG PG PG
Sbjct: 2026 PPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPG 2085

Query: 901  PIGPLGL--------PGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGK 952
            P GP G         PG  G +GPPG +G KG+ GS G  G  G++G+ G KG++G+ G 
Sbjct: 2086 PPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGP 2145

Query: 953  RGPHGLIGKTGNPGERGFQGKPGLQGL---PGSTGDRGLPGEPGLRGLQGDVGPPGEMGM 1009
            RG  G  G  G  G  G +GKPGLQG    PG  G  G PG PG  GL G  GP G  G+
Sbjct: 2146 RGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGL 2205

Query: 1010 EGPPGTEGESG-----------LQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQ 1058
            +G PG  G  G           L G PG  G VG  GS G  G+ G  G+PGAPG +G  
Sbjct: 2206 KGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGAS 2265

Query: 1059 GKDG-----------------------------------------LKGVPGG-------- 1069
            GKDG                                          KG PGG        
Sbjct: 2266 GKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGE 2325

Query: 1070 ------RGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGI-----VGIPGQRGRPGKK 1118
                  RGLPG  GEKGE G  G  G  G  GQ G PGP+G      VG+PG  G PG  
Sbjct: 2326 PGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPP 2385

Query: 1119 GDKG------------------QIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLM 1160
            G KG                  Q GP GE+G  GP G+ G +GP G  G  G +G  G  
Sbjct: 2386 GVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPP 2445

Query: 1161 GPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPG---EDSTVLGPPGPRGEPGPVGDQGE 1217
            G  G PG  G +G +G PG  GLPGP+GE+G PG   ED    G  GPRG  GP G +GE
Sbjct: 2446 GSVGPPGASGLKGDKGDPGV-GLPGPRGERGEPGIRGEDGRP-GQEGPRGLTGPPGSRGE 2503

Query: 1218 RGEPG---AEGYKGH-------VGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKG 1267
            RGE G   + G KG        +G PG RGA G  G  G  G  G++G +G+ G  G+KG
Sbjct: 2504 RGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKG 2563

Query: 1268 KKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTG 1327
             KG PG  G  G+PGL+GLLGP   QG  GA GI G+PG    PGK G+PGIRG  G  G
Sbjct: 2564 SKGEPGDKGSAGLPGLRGLLGP---QGQPGAAGIPGDPGS---PGKDGVPGIRGEKGDVG 2617

Query: 1328 LAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKG 1387
              G   P G+KG  G+ G+ G+ G KG++G  G PG  G  GH+G  G+ G  G  G  G
Sbjct: 2618 FMG---PRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPG 2674

Query: 1388 QPGEYGVQGLTGFQGFPGPKGPE---GDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTG 1444
            + G  G +G  GF G PGPKG +   G+ G  GI G  GP G+ G+ GP       GP G
Sbjct: 2675 KEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGP------PGPPG 2728

Query: 1445 RTGPRGEKGFRGETGPQGPRGQ--PGPPGPPGAPGPR 1479
              GPRG +G +G+ G +GP G+   G PG PGAPG R
Sbjct: 2729 SVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGER 2765



 Score =  776 bits (2003), Expect = 0.0
 Identities = 493/1174 (41%), Positives = 584/1174 (49%), Gaps = 200/1174 (17%)

Query: 488  RGPKGDTGPPGPPGPAG---IPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPG 544
            RG  G  G PG PG AG    PG  G +G  G+PGP G+   PG  GP+GPKG+PG +PG
Sbjct: 1298 RGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGD---PGERGPRGPKGEPG-APG 1353

Query: 545  QPV-------PGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLP--------GEQGIPG- 588
            Q +       PG KGD G SG  GP G  GD G +G PGLPG          GE+G PG 
Sbjct: 1354 QVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGP 1413

Query: 589  -----FAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFI--GSPGEAGQLGPEGERGIPGIR 641
                   G  G PG PG  G  GP G PG KG +G    G+PG  GQ G  GE+G  G  
Sbjct: 1414 GEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPP 1473

Query: 642  GKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPM 701
            G  G KG +GFPG  G+ G  G  G PG  G  G PG  G  G+ GP GP GP G  G  
Sbjct: 1474 GAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEK 1533

Query: 702  GLSGNKGLP--------GIKGDKGEQGTAGELGEPGYPGDKGAVGL-----PGPPGMRGK 748
            G  G  G P        G KG+KG+ G AG  G  G  G++G  GL     PGP G  G 
Sbjct: 1534 GEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGD 1593

Query: 749  SGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGE 808
             GP G TG  G  G SGPPG +G PG  G PG  GP G  G +G +G  GPPG  G  G+
Sbjct: 1594 RGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGK 1653

Query: 809  EGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTG- 867
             G  G  G  G RG  G+KG  G+PG +G  G  G  G  G  GE GP G PG +  TG 
Sbjct: 1654 AGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGP 1713

Query: 868  ---SIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKG 924
                 GE G+RG  GP GP+G+      PG PG PG  G  G  G  G +G PG +GP G
Sbjct: 1714 GAREKGEPGDRGQEGPRGPKGD------PGLPGAPGERGIEGFRGPPGPQGDPGVRGPAG 1767

Query: 925  QRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTG 984
            ++G RGP GL G  G+    G+ G  G  GP+G  GK G+PG  G  G  G QGLPG +G
Sbjct: 1768 EKGDRGPPGLDGRSGLD---GKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSG 1824

Query: 985  DRGLP------GEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVG 1038
              GLP      G+PGL G  G+ G PGE G +G  G  G SG +G  G KG+ G  G +G
Sbjct: 1825 PPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILG 1884

Query: 1039 GTGEPGL--------RGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMG-LPGI-- 1087
              G PGL        +G PG PG  G +G  G  G  G +GLPGE G +GE G +P +  
Sbjct: 1885 PQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDR 1944

Query: 1088 ---------------------------------IGPLGRSGQTGLPGPEGIVGIPGQRGR 1114
                                              GP G SG+ G PG EG +G PG+RG 
Sbjct: 1945 LLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGL 2004

Query: 1115 PGKKGDKGQIGPTG-EVGSRGPP------GKIGKSGPKGARGTRGAVGHLGLMGPDGEPG 1167
             G +GD G  GP G  +G RGPP      G+ GK G  G  G  G VG  G  G  GE G
Sbjct: 2005 KGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERG 2064

Query: 1168 IPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGP-PGPRGEPGPVGDQGERGEPGA--- 1223
              G RG QG+ GP GLPG  G  G PG   +V  P PG  GE GP G +G +GEPG+   
Sbjct: 2065 EKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGD 2124

Query: 1224 EGYKGHVGVPGLRGATGQQGPPGE---PGDQGEQGLKGERGSEGNKGKKGAPGP---SGK 1277
            +G KG  GVPG++G  G+ GP G+   PG  GE+G+ G  G  G +G +G PGP    G 
Sbjct: 2125 QGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGD 2184

Query: 1278 PGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGK-----------------------Q 1314
            PG PG  GL GP G Q   G  G+ G PG+ GPPG+                       Q
Sbjct: 2185 PGPPGAPGLAGPAGPQ---GPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQ 2241

Query: 1315 GLPGIRGGPGRTGLAGAPGPPGV------KGSSGLPGSPGIQGP---------------- 1352
            G PG+ G  G TG  GAPG  G       +GS G+PGSPG+ GP                
Sbjct: 2242 GSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQA 2301

Query: 1353 -------KGEQGLP--------GQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGL 1397
                   KGE+G P        G+PG +G RG  G +G++G  G  G  G PGE G +G 
Sbjct: 2302 VVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGA 2361

Query: 1398 TGFQGF--------------PGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPT 1443
             G +GF              PGP G +GD G+ G+ G  G +G  G TGP G  G  GP+
Sbjct: 2362 PGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPS 2421

Query: 1444 GRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPG 1477
            G  G  G  G  G  GP GP G PG  GPPGA G
Sbjct: 2422 GERGLAGPPGREGIPGPLGPPGPPGSVGPPGASG 2455



 Score =  774 bits (1999), Expect = 0.0
 Identities = 508/1287 (39%), Positives = 606/1287 (47%), Gaps = 295/1287 (22%)

Query: 489  GPKGDTGPPGPPGPAGIPGPS-----GKRGPRGIPGPH---------GNPGLPGLPGPKG 534
            GP+G  G PGP GP G+PG +     G RG RG PGP          G PGLPG PGP+G
Sbjct: 1377 GPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQG 1436

Query: 535  PKGDPG-------FSPGQP-VPGEKGDQGLSGLMGPPGMQGDKGLKGHPGL---PGLPGE 583
            P G PG          G P +PG+ G  G  G  GPPG  G KG +G PG     G  GE
Sbjct: 1437 PVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGE 1496

Query: 584  QGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPG-----------------EA 626
            +G PG AG+ G PG  GR G  GPEG PGP G QG  G PG                 E 
Sbjct: 1497 RGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEK 1556

Query: 627  GQLGPEGERGIPGIRGKKG-----FKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPG 681
            G +GP G RG  G++G++G       G  G  GD GDRGP GL G  G  G +GPPG  G
Sbjct: 1557 GDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKG 1616

Query: 682  LRGSVGPVGPIGPAG------------------IPGPMGLSGNKGLPGIKG---DKGEQG 720
              G  GP GP+GP G                  +PG  G  G +G PG++G   +KG+QG
Sbjct: 1617 DPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQG 1676

Query: 721  TAGELGEPGYPG------DKGAVGLPGPPGM----------------RGKSGPSGQTGDP 758
              GE G  G PG      D+G  G PGPPG                 RG+ GP G  GDP
Sbjct: 1677 DPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDP 1736

Query: 759  GLQGPSG---------PPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEE 809
            GL G  G         PPGP+G PG  G  G+ G  GP GL G  G  G PG  G  G  
Sbjct: 1737 GLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPN 1796

Query: 810  GPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSI 869
            G  G  G+ G  G PG +G  G PGP G  G  G  G  GK G  G  G PG+ G  G  
Sbjct: 1797 GAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRK 1856

Query: 870  GEKGERGSPG------PLGPQGEKGVMGYPGPPGVPGPIGP------------------- 904
            GEKG+ G+ G      P G +G  G++G  GPPG+PGP+GP                   
Sbjct: 1857 GEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRG 1916

Query: 905  -------LGLPGHVGARGPPGS-------------------------------------- 919
                    GLPG  G RG PGS                                      
Sbjct: 1917 ETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPER 1976

Query: 920  -QGPKGQRGSRGP---DGLLGEQGIQGAKGEKGDQGKRGPHGL-IGKTGNPGERGFQG-- 972
             +GPKG  G +GP   +G +G  G +G KG++GD G +GP GL +G+ G PG  G  G  
Sbjct: 1977 RRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEP 2036

Query: 973  -KPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDV 1031
             KPG+ GLPG  G  G  G PG RG +G+ G  GE G +GPPG  G  G  G PG K  V
Sbjct: 2037 GKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSV 2096

Query: 1032 -----GTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPG 1086
                 G +G  G  G  G +GEPG+ G++G +G  G+ G+ G RG PG  G+ G  GLPG
Sbjct: 2097 DEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPG 2156

Query: 1087 IIGPLGRSGQTGL------PGPEGIVGIPGQRGRPGKKGDKGQIGPTG---EVGSRGPPG 1137
              G  G  G+ GL      PGP G  G PG  G PG  G  G  GP+G   E G  GPPG
Sbjct: 2157 ERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPG 2216

Query: 1138 KIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGP------SGLPGPKGEKG 1191
            + G +GP GA G  G  G  GL+GP G PG+PG  G  G+PG       SG  G +G  G
Sbjct: 2217 R-GLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPG 2275

Query: 1192 YPGEDSTVLGPPGPRGEPGPVGD-----------QGERGEPGA--------EGYKGHVGV 1232
             PG    + GP GP+GEPGP G            +GE+G PG          G KG  G+
Sbjct: 2276 VPGSPG-LPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGL 2334

Query: 1233 PGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKG-----APGPSGKPGI------P 1281
            PG RG  G+ G  GEPGD GE G KG  G +G KG  G     +PGP G PG+      P
Sbjct: 2335 PGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLP 2394

Query: 1282 GL---------------------------QGLLGPKGIQGYHGADGISGNPGKIGPPGKQ 1314
            GL                           +GL GP G +G  G  G  G PG +GPPG  
Sbjct: 2395 GLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGAS 2454

Query: 1315 GL-----------PGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPG 1363
            GL           PG RG  G  G+ G  G PG +G  GL G PG +G +GE+G  G  G
Sbjct: 2455 GLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAG 2514

Query: 1364 IQG----------------------KRGHRGAQGDQGPCGD------PGLKGQPGEYGVQ 1395
            ++G                      +RG RG  GD+GP GD       G KG+PG+ G  
Sbjct: 2515 LKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSA 2574

Query: 1396 GLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFR 1455
            GL G +G  GP+G  G AGI G  G  G  G  G  G  G  G +GP G  G RG KG  
Sbjct: 2575 GLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGAC 2634

Query: 1456 GETGPQGPRGQPGPPGPPGAPGPRKQM 1482
            G  G +G +G+ GPPG PG  G + +M
Sbjct: 2635 GLDGEKGDKGEAGPPGRPGLAGHKGEM 2661



 Score =  719 bits (1857), Expect = 0.0
 Identities = 457/1069 (42%), Positives = 529/1069 (49%), Gaps = 147/1069 (13%)

Query: 532  PKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFA- 590
            PKG KG+PG            + GL G +GPPG   D GL   PG  G PG QG PG A 
Sbjct: 1252 PKGQKGEPG------------EMGLRGQVGPPG---DPGL---PGRTGAPGPQGPPGSAT 1293

Query: 591  --GNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKG 648
              G  G PG  GR G  G  GNPG  GA G  GSPG  G  G  GERG  G +G+ G  G
Sbjct: 1294 AKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPG 1353

Query: 649  R------QGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGL-----------RGSVGPVGP 691
            +       G PG  GD GP+G  G  G +G  GP G PGL           RG  GP GP
Sbjct: 1354 QVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGP 1413

Query: 692  ----IGPA-----GIPGPMGLSGNKGLPGIKGDKG--EQGTAGELGEPGYPGDKGAVGLP 740
                I P      G+PG  G  G  G PG KG+KG  E G  G  G+PG PG++G  G P
Sbjct: 1414 GEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPP 1473

Query: 741  ---GPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPP 797
               GP G RG  GP G+ G+ G +GP GP G  G PG  G PG  GPEGP G  G +G  
Sbjct: 1474 GAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEK 1533

Query: 798  GPPGLKGTQGEEGPI-----GAFGELGPRGKPGQKGYAGEPGPEGL-----KGEVGDQGN 847
            G PG  G     GP      G  G++GP G  G  G  GE GP GL      G  GD G+
Sbjct: 1534 GEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGD 1593

Query: 848  IGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQ------GEKGVMGYPGPPGVPGP 901
             G IG TG  G PG+ G  G  G+ G  G PGP+GP+      GEKG  G PG PG+PG 
Sbjct: 1594 RGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGK 1653

Query: 902  IGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLI-- 959
             G  GL G  G RGP G    KG +G  G DG  G  G  G KG++G+ G  GP G +  
Sbjct: 1654 AGERGLRGAPGVRGPVGE---KGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVD 1710

Query: 960  -----------GKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMG 1008
                       G  G  G RG +G PGL G PG  G  G  G PG +G  G  GP GE G
Sbjct: 1711 TGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKG 1770

Query: 1009 MEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGL---QGKDGLKG 1065
              GPPG +G SGL G+PGA G  G  G+ G  G+PG  G PG  GE+GL    G  GL G
Sbjct: 1771 DRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPG 1830

Query: 1066 VPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIG 1125
             PG  G PG +G+ GE G PG  G  G  G +G  G EG  G  G+RG PG  G +G  G
Sbjct: 1831 KPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPG 1890

Query: 1126 PTGEVG--SRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPG------------- 1170
              G VG   +G PG  G +GPKG RG  G+ G  GL G  G  G PG             
Sbjct: 1891 LPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAG 1950

Query: 1171 --------------------------YRGHQGQPGPSGLPGPKGEKGYPGEDSTV--LGP 1202
                                       RG +G  G  G PG +G  G+PGE       G 
Sbjct: 1951 IKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGD 2010

Query: 1203 PGPRGEPG-PVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERG 1261
            PGP+G PG  +G++G  G  G  G  G  G+PGL G  G  G  G PG++GE+G KGERG
Sbjct: 2011 PGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERG 2070

Query: 1262 SEGNKGKKGAPGPSGKPGIPGLQ--------GLLGPKGIQGYHGADGISGNPGKIGPPGK 1313
             +G  G  G PG  G PG PG +        GL G +G  G  GA G  G+ G  GP G 
Sbjct: 2071 EQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGD 2130

Query: 1314 QGLPGI---RGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGH 1370
            +G+PGI   RG PG  G  G PG PG +G +G  G PG+QGP+G  G  G  G  G  G 
Sbjct: 2131 RGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGA 2190

Query: 1371 RGAQGDQGPCGDPGLKGQPGE-----YGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPI 1425
             G  G  GP G  GLKG+PGE      G+ G TG  G PGP GP G  G  G  G  G +
Sbjct: 2191 PGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQV 2250

Query: 1426 GHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPG 1474
            G  G  G  GR+G  G  G  G  G  G  G  GP GP+G+PGP G PG
Sbjct: 2251 GETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPG 2299



 Score =  712 bits (1838), Expect = 0.0
 Identities = 456/1105 (41%), Positives = 538/1105 (48%), Gaps = 218/1105 (19%)

Query: 489  GPKGDTGPPGPPGPAGI-------------PGPSGKRGPRGIPGPHGNPGLPGLPGPKGP 535
            GPKGD G PGPPGP G              PG  G+ GPRG   P G+PGLPG PG +G 
Sbjct: 1691 GPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRG---PKGDPGLPGAPGERGI 1747

Query: 536  KGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGS 595
            +G  G    Q  PG +G  G  G  GPPG+ G  GL G PG  G  G  G    AG  G 
Sbjct: 1748 EGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGA---AGKAGD 1804

Query: 596  PGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLG---PEGERGIPGIRGKKGFKGRQGF 652
            PG  G  GL G +G PGP G  G  G PGE G+ G     GE G PG  G+KG KG  G 
Sbjct: 1805 PGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGA 1864

Query: 653  PGDFGDRGPAGLDGSPGLVGGTGPPG-----------FPGLRGSVGPVGPIGPAGIPGPM 701
             G  G  GP G  G+PG++G  GPPG           FPG+ G  GP G  G  G  G  
Sbjct: 1865 SGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQ 1924

Query: 702  GLSGNKGLPGI---------------------------------------------KGDK 716
            GL G +GL G                                              KGD 
Sbjct: 1925 GLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDS 1984

Query: 717  GEQGTAGELGEPGYPG------DKGAVGLPGPPGM----RGKSGPSGQTGDPGLQGPSGP 766
            GEQG  G+ G  G+PG      D+G  G  GPPG+    RG  GPSG  G+PG  G  G 
Sbjct: 1985 GEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGL 2044

Query: 767  PGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGA-----------F 815
            PG  G  G+ G PG+ G  G KG  G +G  GPPGL GT G  GP G             
Sbjct: 2045 PGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLS 2104

Query: 816  GELGP------RGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSI 869
            GE GP      +G+PG  G  G  G  G+ G  GD+G  G  G+ G  GLPGE GM G  
Sbjct: 2105 GEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPE 2164

Query: 870  GE---KGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGS-----QG 921
            G+   +G RG PGP+G  G+ G  G PG  G  GP GP GL G  G  GPPG       G
Sbjct: 2165 GKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTG 2224

Query: 922  PKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPG 981
              G  G  GP GL+G QG  G  G+ G+ GK G  G  G +G  G+RG  G PG  GLPG
Sbjct: 2225 AVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPG 2284

Query: 982  STGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESG-LQGEPGAKGDVGTAGSVGGT 1040
              G +G PG  G  G Q  VG PG  G +G PG  G +G L GEPGAKGD G  G  G  
Sbjct: 2285 PVGPKGEPGPTGAPG-QAVVGLPGAKGEKGAPG--GLAGDLVGEPGAKGDRGLPGPRGEK 2341

Query: 1041 GEPGLRGEPGAPGEEGLQGKDGLKG--------VPGGRGLPGEDGEKGEMGLPGIIGPLG 1092
            GE G  GEPG PGE+G +G  G KG        VPG  G PG  G KG++GLPG+ G  G
Sbjct: 2342 GEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPG 2401

Query: 1093 RSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRG 1152
              G  G  GP G +G PG  G  G  G  G+ G  G +G  GPPG +G  G  G +G +G
Sbjct: 2402 VVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKG 2461

Query: 1153 AVGHLGLMGPDGEPGIPGYRGHQGQPG---PSGLPGPKGEKGYPGE-------------- 1195
              G +GL GP GE G PG RG  G+PG   P GL GP G +G  GE              
Sbjct: 2462 DPG-VGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKG 2520

Query: 1196 -DSTVLGPPGPRGEPGPVGDQGERG------------EPGAEGYKGH------VGVPGLR 1236
              + +LGPPGPRG  G +G++G RG            +PG +G KG        G+PGLR
Sbjct: 2521 DSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLR 2580

Query: 1237 GATGQQGPPGE---PGD---------------------------QGEQGLKGERGSEGNK 1266
            G  G QG PG    PGD                           +GE+G+KG  G +G K
Sbjct: 2581 GLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEK 2640

Query: 1267 GKKGAPGPSGKPGI------------------PGLQGLLGPKGIQGYHGADGISGNPGKI 1308
            G KG  GP G+PG+                  PG +GL+GPKG +G+ G  G  G+ G+ 
Sbjct: 2641 GDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGE- 2699

Query: 1309 GPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQ-----PG 1363
               G++G PGI G PG +G  G+ GPPG  GS G  G  G+QG KGE+G PG+     PG
Sbjct: 2700 --KGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPG 2757

Query: 1364 IQGKRGHRGAQGDQGPCGDPGLKGQ 1388
            + G  G RG QG  GP G  G KG+
Sbjct: 2758 VPGAPGERGEQGRPGPAGPRGEKGE 2782



 Score =  659 bits (1699), Expect = 0.0
 Identities = 419/1001 (41%), Positives = 487/1001 (48%), Gaps = 163/1001 (16%)

Query: 631  PEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVG 690
            P+G++G PG  G +G  G  G PG  G  G  G  G PG     G  GFPG  G  G  G
Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPG 1311

Query: 691  PIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSG 750
              G  G PG  GL G+ GLPG +GD GE+G  G  GEPG PG    +G  G PG+ G+ G
Sbjct: 1312 RAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQ--VIGGEG-PGLPGRKG 1368

Query: 751  PSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGP------PGLKG 804
              G +G PG +GP G PGP G P   G+PG    +G KG  G RGPPGP      PG  G
Sbjct: 1369 DPGPSGPPGPRGPLGDPGPRGPP---GLPG-TAMKGDKGDRGERGPPGPGEGGIAPGEPG 1424

Query: 805  TQGEEGPIGAFGELGPRGKPGQKGYA--GEPGPEGLKGEVGDQGNIGKIGETGPVGLPGE 862
              G  G  G  G +GP GK G+KG +  G PG  G  G  G+QG  G  G  GP G  G 
Sbjct: 1425 LPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGF 1484

Query: 863  VGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGS--- 919
             G  G  GEKGERG PGP G +G  GV G PG  G  GP GP G  G  G  G PG    
Sbjct: 1485 PGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAV 1544

Query: 920  -----QGPKGQRGSRGPDGLLGEQGIQGAK-----------GEKGDQGKRGPHGLIGKTG 963
                  GPKG++G  GP G  G  G+QG +           G KGD G RGP GL G+ G
Sbjct: 1545 VGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAG 1604

Query: 964  NPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQG 1023
             PG+ G  G+ G  G PG  G  G  G  G  G +GD GPPG+ G+   PG  GE GL+G
Sbjct: 1605 PPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGL---PGKAGERGLRG 1661

Query: 1024 EPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDG-EKGEM 1082
             PG +G VG  G  G  GE G  G PG+ G +G +G+ G  G PG     G    EKGE 
Sbjct: 1662 APGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEP 1721

Query: 1083 GLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKS 1142
            G  G  GP G  G  GLPG  G  GI G RG PG +GD G  GP GE G RGPPG  G+S
Sbjct: 1722 GDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRS 1781

Query: 1143 GPKGARGTRGAVGHLGLMGPDGEP---GIPGYRGHQGQPGPSGLP--------------- 1184
            G  G  G  G  G  G  G  G+P   G+PG RG QG PGPSG P               
Sbjct: 1782 GLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLN 1841

Query: 1185 GPKGEKGYPGEDSTV--------------LGPPGPRGEPGPVGDQGERGEPGAEGYKGHV 1230
            G  GE G PGED                  GP G RG PG +G QG  G PG  G  G  
Sbjct: 1842 GKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQ- 1900

Query: 1231 GVPGLRGATGQQGPPGEPGDQGEQGLKGE------------------------------- 1259
            G PG+ G TG +G  GE G +GEQGL GE                               
Sbjct: 1901 GFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIV 1960

Query: 1260 -----------------RGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGIS 1302
                             RG +G+ G++G PG  G  G PG +GL G +G  G  G  G++
Sbjct: 1961 ETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLA 2020

Query: 1303 -------GNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSS------------GL 1343
                   G  G  G PGK G+PG+ G  G  G AG PG  G +G              GL
Sbjct: 2021 LGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGL 2080

Query: 1344 PGSPGIQGPKGEQ-----------GLPGQPGIQGKRGHRGAQGDQGPCGD---PGLKGQP 1389
            PG+PG  GP G +           G  G PG++G +G  G+ GDQGP GD   PG+KG  
Sbjct: 2081 PGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDR 2140

Query: 1390 GEYGVQGLTGFQGFPGPK---GPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRT 1446
            GE G +G  G  G PG +   GPEG  G+ G  GP GP+G  G+ GP G  G+ GP G  
Sbjct: 2141 GEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQ 2200

Query: 1447 GPRGEKGFRGE--------TGPQGPRGQPGPPGPPGAPGPR 1479
            GP G KG  GE        TGP G  G PGPPGP G  GP+
Sbjct: 2201 GPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQ 2241



 Score =  624 bits (1608), Expect = e-178
 Identities = 385/839 (45%), Positives = 455/839 (54%), Gaps = 86/839 (10%)

Query: 485  EYLRGPKGDTG---PPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLP----GLPGPKGPKG 537
            E  RGPKGD+G   PPG  GP G PG  G +G RG PGP G PGL     G PGP G  G
Sbjct: 1975 ERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAG 2034

Query: 538  DPGFSPGQP-VPGEKGDQGLSGLMGPPGMQGDKGLKGH------PGLPGLPGEQGIPGFA 590
            +PG  PG P +PG  G  G +G  G  G +G+KG +G       PGLPG PG  G PG  
Sbjct: 2035 EPG-KPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPK 2093

Query: 591  GNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGI---RGKKGFK 647
             ++  PG     GL+G +G PG KGA+   G PG  G  GP+G+RG+PGI   RG+ G +
Sbjct: 2094 VSVDEPG----PGLSGEQGPPGLKGAK---GEPGSNGDQGPKGDRGVPGIKGDRGEPGPR 2146

Query: 648  GRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNK 707
            G+ G PG  G+RG AG +G PGL G  GPPG  G  G  GP G  G AG  GP G SG K
Sbjct: 2147 GQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLK 2206

Query: 708  GLPGIKG--DKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSG 765
            G PG  G   +G  G  G +G PG PG  G VG  G PG+ G+ G +G+ G PG  G SG
Sbjct: 2207 GEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASG 2266

Query: 766  PPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPP--GLKGTQGEEG-PIGAFGELGPRG 822
              G  G PG  G PG  GP GPKG  G  G PG    GL G +GE+G P G  G+L   G
Sbjct: 2267 KDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDL--VG 2324

Query: 823  KPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLG 882
            +PG KG  G PGP G KGE G  G  G  GE G  G PG  G  G  G  G  GSPGP G
Sbjct: 2325 EPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPG-VGVPGSPGPPG 2383

Query: 883  PQGEKGVMGYPGPPGVP---------GPIGPLGLPGHVGAR---GPPGSQGPKGQRGSRG 930
            P G KG +G PG PG P         GP G +G PG  G R   GPPG +G  G  G  G
Sbjct: 2384 PPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPG 2443

Query: 931  PDGLLGEQGIQGAKGEKGD--------QGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGS 982
            P G +G  G  G KG+KGD        +G+RG  G+ G+ G PG+   +G  GL G PGS
Sbjct: 2444 PPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQ---EGPRGLTGPPGS 2500

Query: 983  TGDRGLPGEPGLRGLQGD-------VGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAG 1035
             G+RG  G+ G  GL+GD       +GPPG  G +G  G  G  GL G+ G +GD G  G
Sbjct: 2501 RGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPG 2560

Query: 1036 SVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSG 1095
              G  GEPG +G  G PG  GL G    +G PG  G+PG+ G  G+ G+PGI G  G  G
Sbjct: 2561 DKGSKGEPGDKGSAGLPGLRGLLGP---QGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVG 2617

Query: 1096 QTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVG 1155
              G  G +G  G+ G  G  G+KGDKG+ GP G  G  G  G++G+    G  G  GA G
Sbjct: 2618 FMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGE---PGVPGQSGAPG 2674

Query: 1156 HLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGE------P 1209
              GL+GP G+      RG  GQPGP G  G KGE+G PG    + G PGP G       P
Sbjct: 2675 KEGLIGPKGD------RGFDGQPGPKGDQGEKGERGTPG----IGGFPGPSGNDGSAGPP 2724

Query: 1210 GPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGK 1268
            GP G  G RG  G +G KG  G PG R   G  G PG PG++GEQG  G  G  G KG+
Sbjct: 2725 GPPGSVGPRGPEGLQGQKGERGPPGER-VVGAPGVPGAPGERGEQGRPGPAGPRGEKGE 2782



 Score =  513 bits (1321), Expect = e-145
 Identities = 320/718 (44%), Positives = 373/718 (51%), Gaps = 70/718 (9%)

Query: 805  TQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVG 864
            TQ    P   +   G +G+PG+ G  G+ GP       GD G  G+ G  GP G P    
Sbjct: 1240 TQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPP------GDPGLPGRTGAPGPQGPP---- 1289

Query: 865  MTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKG 924
              GS   KGERG PG  G  G  G  G PG PG PG  G  GLP   G RG PG +GP+G
Sbjct: 1290 --GSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLP---GPRGDPGERGPRG 1344

Query: 925  QRGSRG-PDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPG--LQGLPG 981
             +G  G P  ++G +G  G  G KGD G  GP G  G  G+PG RG  G PG  ++G  G
Sbjct: 1345 PKGEPGAPGQVIGGEG-PGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKG 1403

Query: 982  STGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTG 1041
              G+RG PG PG  G+      PGE G+ G PG+ G  G  G PG KG+ G +      G
Sbjct: 1404 DRGERGPPG-PGEGGI-----APGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSED----G 1453

Query: 1042 EPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLP---GEDGEKGEMGLPGIIGPLGRSGQTG 1098
             PGL G+PG+PGE+G +G  G  G  G RG P   GE GEKGE G PG  G  G  G  G
Sbjct: 1454 APGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAG 1513

Query: 1099 LPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEV-----GSRGPPGKIGKSGPKGARGTRGA 1153
             PG +G  G PG  GR G+KG+ G+ G    V     G +G  G +G +GP+GA G +G 
Sbjct: 1514 RPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGE 1573

Query: 1154 VGHLGLM-----GPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGE 1208
             G  GL+     GP G+PG  G  G  G+ GP G  GP GEKG PG      GP GPRG 
Sbjct: 1574 RGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPP-GPVGPRGR 1632

Query: 1209 PGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQ---GEQGLKGERGSEGN 1265
             G VG++G+ G PG  G  G  G  GLRGA G +GP GE GDQ   GE G  G  GS G 
Sbjct: 1633 DGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGP 1692

Query: 1266 KGKKGAPGP----------------SGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIG 1309
            KG +G PGP                 G+PG  G +G  GPKG  G  GA G  G  G  G
Sbjct: 1693 KGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRG 1752

Query: 1310 PPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRG 1369
            PPG QG PG+RG  G  G  G PG  G  G  G PG+ G  GP G  G  G PG  G  G
Sbjct: 1753 PPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPG 1812

Query: 1370 HRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGP------KGPEGDAGIVGISGPKG 1423
             RG QG  GP G PGL G+PGE G  GL G  G PG       KG +GD+G  G  G  G
Sbjct: 1813 LRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDG 1872

Query: 1424 PIGHRGNTGPLGREGIIGPTGRTGPRGE--KGFRGETGPQGPRGQPGPPGPPGAPGPR 1479
            P G RG  G LG +G  G  G  GP G+   G  G TGP+G RG+ G  G  G PG R
Sbjct: 1873 PKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGER 1930



 Score =  501 bits (1291), Expect = e-141
 Identities = 312/690 (45%), Positives = 362/690 (52%), Gaps = 77/690 (11%)

Query: 827  KGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGE 886
            KG  GEPG  GL+G+VG  G+ G  G TG    PG  G  GS   KGERG PG  G  G 
Sbjct: 1253 KGQKGEPGEMGLRGQVGPPGDPGLPGRTGA---PGPQGPPGSATAKGERGFPGADGRPGS 1309

Query: 887  KGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDG-LLGEQGIQGAKG 945
             G  G PG PG PG  G  GLPG    RG PG +GP+G +G  G  G ++G +G  G  G
Sbjct: 1310 PGRAGNPGTPGAPGLKGSPGLPG---PRGDPGERGPRGPKGEPGAPGQVIGGEG-PGLPG 1365

Query: 946  EKGDQGKRGPHGLIGKTGNPGERGFQGKPG--LQGLPGSTGDRGLPGEPGLRGLQGDVGP 1003
             KGD G  GP G  G  G+PG RG  G PG  ++G  G  G+RG PG PG  G+      
Sbjct: 1366 RKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPG-PGEGGIA----- 1419

Query: 1004 PGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGL 1063
            PGE G+ G PG+ G  G  G PG KG+ G +      G PGL G+PG+PGE+G +G  G 
Sbjct: 1420 PGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSED----GAPGLPGQPGSPGEQGPRGPPGA 1475

Query: 1064 KGVPGGRGLPG---EDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGD 1120
             G  G RG PG   E GEKGE G PG  G  G  G  G PG +G  G PG  GR G+KG+
Sbjct: 1476 IGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGE 1535

Query: 1121 KGQIGPTGEVGS-----RGPPGKIGKSGPKGARGTRGAVGHLGLM-----GPDGEPGIPG 1170
             G+ G    VG      +G  G +G +GP+GA G +G  G  GL+     GP G+PG  G
Sbjct: 1536 PGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRG 1595

Query: 1171 YRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHV 1230
              G  G+ GP G  GP GEKG PG      GP GPRG  G VG++G+ G PG  G  G  
Sbjct: 1596 PIGLTGRAGPPGDSGPPGEKGDPGRPGPP-GPVGPRGRDGEVGEKGDEGPPGDPGLPGKA 1654

Query: 1231 GVPGLRGATGQQGPPGEPGDQG---EQGLKGERGSEGNKGKKGAPGP------------- 1274
            G  GLRGA G +GP GE GDQG   E G  G  GS G KG +G PGP             
Sbjct: 1655 GERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPG 1714

Query: 1275 ---SGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGA 1331
                G+PG  G +G  GPKG  G  GA G  G  G  GPPG QG PG+RG  G  G  G 
Sbjct: 1715 AREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGP 1774

Query: 1332 PGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGE 1391
            PG  G  G  G PG+ G  GP G  G  G PG  G  G RG QG  GP G PGL G+PGE
Sbjct: 1775 PGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGE 1834

Query: 1392 YGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGE 1451
             G  GL G  G PG  G +G  G             +G++G  GREG      R GP+GE
Sbjct: 1835 DGKPGLNGKNGEPGDPGEDGRKG------------EKGDSGASGREG------RDGPKGE 1876

Query: 1452 KGFRGETGPQGPRGQPGPPGPPGAPGPRKQ 1481
            +G  G  GPQGP      PG PG  GP  Q
Sbjct: 1877 RGAPGILGPQGP------PGLPGPVGPPGQ 1900



 Score =  439 bits (1128), Expect = e-122
 Identities = 274/627 (43%), Positives = 334/627 (53%), Gaps = 63/627 (10%)

Query: 893  PGPPGVPGPIGPLGLPGHVGARG---PPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGD 949
            P P  V  P G  G PG +G RG   PPG  G  G+ G+ GP G     G   AKGE+G 
Sbjct: 1244 PEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQG---PPGSATAKGERGF 1300

Query: 950  QGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEM-G 1008
             G  G  G  G+ GNPG     G PGL+G PG  G RG PGE G RG +G+ G PG++ G
Sbjct: 1301 PGADGRPGSPGRAGNPGT---PGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIG 1357

Query: 1009 MEGP--PGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGE--EGLQGKDGLK 1064
             EGP  PG +G+ G  G PG +G +G         +PG RG PG PG   +G +G  G +
Sbjct: 1358 GEGPGLPGRKGDPGPSGPPGPRGPLG---------DPGPRGPPGLPGTAMKGDKGDRGER 1408

Query: 1065 GVPG-GRG--LPGEDGEKGEMGLPGIIGPLGRSGQTGLPGP--EGIVGIPGQRGRPGKKG 1119
            G PG G G   PGE G  G  G PG  GP+G  G+ G  G   +G  G+PGQ G PG++G
Sbjct: 1409 GPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQG 1468

Query: 1120 DKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPG 1179
             +G  G  G  G RG PG +G++G KG RG  G  G  GL G  G PG    +G +G PG
Sbjct: 1469 PRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGA---KGPEGPPG 1525

Query: 1180 PSGLPGPKGEKGYPGEDSTVLGPP--GPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRG 1237
            P+G  G KGE G PG D  V+GP   GP+GE G VG  G RG  G +G +G  G+     
Sbjct: 1526 PTGRQGEKGEPGRPG-DPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLV---- 1580

Query: 1238 ATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHG 1297
              G  GP G+PGD+G  GL G  G  G+ G    PG  G PG PG  G +GP+G  G  G
Sbjct: 1581 LPGDPGPKGDPGDRGPIGLTGRAGPPGDSGP---PGEKGDPGRPGPPGPVGPRGRDGEVG 1637

Query: 1298 ADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQG 1357
              G  G PG  G PGK G  G+RG PG  G  G  G  G  G  G  GSPG  GPKG++G
Sbjct: 1638 EKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRG 1697

Query: 1358 LPGQPGI-------------QGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFP 1404
             PG PG              +G+ G RG +G +GP GDPGL G PGE G++G   F+G P
Sbjct: 1698 EPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEG---FRGPP 1754

Query: 1405 GPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPR 1464
            GP+G  G  G  G  G +GP G  G +G  G+ G  GP+G  G  G+ G  G  G  G R
Sbjct: 1755 GPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLR 1814

Query: 1465 GQPGPPGP------PGAPGPRKQMDIN 1485
            G+ G PGP      PG PG   +  +N
Sbjct: 1815 GEQGLPGPSGPPGLPGKPGEDGKPGLN 1841



 Score =  313 bits (801), Expect = 1e-84
 Identities = 197/449 (43%), Positives = 235/449 (52%), Gaps = 46/449 (10%)

Query: 1046 RGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGI 1105
            +G+ G PGE GL+G+    G PG  GLPG  G  G  G PG        G+ G PG +G 
Sbjct: 1253 KGQKGEPGEMGLRGQ---VGPPGDPGLPGRTGAPGPQGPPG---SATAKGERGFPGADGR 1306

Query: 1106 VGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGE 1165
             G PG+ G PG  G  G  G  G  G RG PG+    GP+G +G  GA G +  +G +G 
Sbjct: 1307 PGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGE---RGPRGPKGEPGAPGQV--IGGEG- 1360

Query: 1166 PGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEP--GPVGDQGERGEPG- 1222
            PG+PG    +G PGPSG PGP+G  G PG      GPPG  G    G  GD+GERG PG 
Sbjct: 1361 PGLPG---RKGDPGPSGPPGPRGPLGDPGPR----GPPGLPGTAMKGDKGDRGERGPPGP 1413

Query: 1223 AEG--YKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGI 1280
             EG    G  G+PGL G+ G QGP G PG +GE+G   E G+ G  G+ G+PG  G  G 
Sbjct: 1414 GEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKG-DSEDGAPGLPGQPGSPGEQGPRGP 1472

Query: 1281 PGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGS 1340
            PG    +GPKG +G+ G  G +G  G+ GPPG  G           GL G  G PG KG 
Sbjct: 1473 PGA---IGPKGDRGFPGPLGEAGEKGERGPPGPAG---------SRGLPGVAGRPGAKGP 1520

Query: 1341 SGLPGSPGIQGPKGEQGLPGQPGIQGKR--GHRGAQGDQGPCGDPGLKGQPGEYGVQGLT 1398
             G PG  G QG KGE G PG P + G    G +G +GD GP G  G  G  GE G  GL 
Sbjct: 1521 EGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLV 1580

Query: 1399 GFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGET 1458
               G PGPKG  GD G +G++G  GP G  G  G  G  G  GP G  GPRG  G  GE 
Sbjct: 1581 -LPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGE- 1638

Query: 1459 GPQGPRGQPGPPGPPGAPGPRKQMDINAA 1487
                 +G  GPPG PG PG   +  +  A
Sbjct: 1639 -----KGDEGPPGDPGLPGKAGERGLRGA 1662



 Score =  201 bits (510), Expect = 7e-51
 Identities = 116/261 (44%), Positives = 141/261 (54%), Gaps = 35/261 (13%)

Query: 488  RGPKGDTGPPGP------PGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGF 541
            RG KGD G  GP       GP G  G  G +G +G PG  G+ GLPGL G  GP+G PG 
Sbjct: 2532 RGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGA 2591

Query: 542  S-----PGQP----VPGEKGDQGLSGLMGPPGMQGDKGLKGHPGL---------PGLPGE 583
            +     PG P    VPG +G++G  G MGP G++G++G+KG  GL          G PG 
Sbjct: 2592 AGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGR 2651

Query: 584  QGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGK 643
             G+ G  G +G PG PG+ G  G EG  GPKG +GF G PG  G  G +GERG PGI   
Sbjct: 2652 PGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGI--- 2708

Query: 644  KGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGP--IGPAGIPGPM 701
                   GFPG  G+ G AG  G PG VG  GP G  G +G  GP G   +G  G+PG  
Sbjct: 2709 ------GGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAP 2762

Query: 702  GLSGNKGLPGIKGDKGEQGTA 722
            G  G +G PG  G +GE+G A
Sbjct: 2763 GERGEQGRPGPAGPRGEKGEA 2783


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score =  782 bits (2020), Expect = 0.0
 Identities = 486/1147 (42%), Positives = 564/1147 (49%), Gaps = 172/1147 (14%)

Query: 494  TGPPGPPG----------------------PAGIPGPSGKRGPRGIPGPHGNPGL---PG 528
            T PP PP                       PAG  G  G  GP G+PGP G+ G     G
Sbjct: 449  TEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVG 508

Query: 529  LPGPKGPKGDPGFSP-GQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHP---GLPGLPGE- 583
             PGPKG KGD G  P GQ   GEKG++G  GL GPPG  G KG++G P   G PGLPGE 
Sbjct: 509  APGPKGEKGDVGIGPFGQ---GEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEV 565

Query: 584  --------QGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGER 635
                     G+PG  G +G+PG  G +G  G  G  G +G  GF G PG+ GQ G  G  
Sbjct: 566  GMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPS 625

Query: 636  GIPGIRGKKGFKGRQGFPGDFG----DRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGP 691
            G+ G +G+KG  G  G PG  G      G  G  G+PG  G  G PG PG RG +GP G 
Sbjct: 626  GVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGR 685

Query: 692  IGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGP 751
             GP G+ G  G  G+ G PGI G  G QG  G  G PG PG  G+ GLPG  G  GK GP
Sbjct: 686  DGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGP 745

Query: 752  SGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGP 811
             G TG PG  GP+GPPGP   PG  G PG+ G +G  G  G RG  G  GL G  GE+G 
Sbjct: 746  PGPTGPPGKDGPNGPPGP---PGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGE 802

Query: 812  IGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVG------- 864
             G  G  G  G  G+KG  GE G  GL G  GD+G  G+ G  GP GLPG          
Sbjct: 803  AGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPR 862

Query: 865  MTGSIGEKGERGSP---------------GPLGPQGEKGVMGYPGPPGVPGPIGPLGLPG 909
            M G  G KGE+G P               GP GP G  G  G  G  G PG  G  G PG
Sbjct: 863  MPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPG 922

Query: 910  HVGA---RGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPG 966
            HVGA    GPPGS G  G RG+ G DG  GE+G  G +G  G  G RG  G  G  G PG
Sbjct: 923  HVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG 982

Query: 967  ERGFQGKPGLQGLPG--------------------------STGDRGLPGEPGLRGLQGD 1000
             +G  G+PGL+G PG                            GDRG PG PG  G +GD
Sbjct: 983  -KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGD 1041

Query: 1001 --VGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPG-------- 1050
              +G  G  G  GPPG +G  G +G PG  G  G AG  G  G PG RG PG        
Sbjct: 1042 PGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLL 1101

Query: 1051 APGEEGLQGKDGLKGV-PGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIP 1109
            +PG+  L  KD      PG  GLPG  G KG+ G+PG  G  G  G+ G  GP G+ G P
Sbjct: 1102 SPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPP 1161

Query: 1110 GQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIP 1169
            G  G  G +G++G  G  G+ G +G PG  G  GP G  G  GA G  G  GP G  G P
Sbjct: 1162 GIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSP 1221

Query: 1170 GYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGD------QGERGEPGA 1223
            G  G  G  GPSGLPG  GE+G  G D    G PGP GEPG  G+      +G RG PG 
Sbjct: 1222 GKEGPPGPQGPSGLPGIPGEEGKEGRD----GKPGPPGEPGKAGEPGLPGPEGARGPPGF 1277

Query: 1224 EGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGL 1283
            +G+ G  G PG RG +G  G PG+ G  G+ G  G  G +G +G +G PG +G PG PG 
Sbjct: 1278 KGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGE 1337

Query: 1284 QGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGL 1343
             G  G  G +G  G +G  G PG +GP G  G PG +G PG+ G+ G PG PG KG  G 
Sbjct: 1338 PGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGD 1397

Query: 1344 PGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQ------GPCGDPGLKGQPGEYGVQG- 1396
            PG  G +GP G +G PG PGI G +GH G  G Q      GP G PG  GQPG  G++G 
Sbjct: 1398 PGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGE 1457

Query: 1397 ----------------------------------LTGFQGFPGPKGPEGDAGIVGISGPK 1422
                                              +   QG PGP GP G  G+ G +GP 
Sbjct: 1458 SPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPM 1517

Query: 1423 GPIGHRGNTGPLGREGIIGPTGRTGPRGEK-----GFRGETGPQGPRGQPGPP-----GP 1472
            G  G  G  G  G  G IGP G  G +G+      G RGE GP G  GQPG P     G 
Sbjct: 1518 GEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGL 1577

Query: 1473 PGAPGPR 1479
            PG PGP+
Sbjct: 1578 PGIPGPQ 1584



 Score =  771 bits (1991), Expect = 0.0
 Identities = 480/1140 (42%), Positives = 559/1140 (49%), Gaps = 174/1140 (15%)

Query: 502  PAGIPGPSGKRGPRGIPGPHGNPGL---PGLPGPKGPKGDPGFSP-GQPVPGEKGDQGLS 557
            PAG  G  G  GP G+PGP G+ G     G PGPKG KGD G  P GQ   GEKG++G  
Sbjct: 479  PAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQ---GEKGEKGSL 535

Query: 558  GLMGPPGMQGDKGLKGHPGL---PGLPGE---------QGIPGFAGNIGSPGYPGRQGLA 605
            GL GPPG  G KG++G PG    PGLPGE          G+PG  G +G+PG  G +G  
Sbjct: 536  GLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEK 595

Query: 606  GPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGD----RGP 661
            G  G  G +G  GF G PG+ GQ G  G  G+ G +G+KG  G  G PG  G      G 
Sbjct: 596  GTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGL 655

Query: 662  AGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGT 721
             G  G+PG  G  G PG PG RG +GP G  GP G+ G  G  G+ G PGI G  G QG 
Sbjct: 656  KGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGP 715

Query: 722  AGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQ 781
             G  G PG PG  G+ GLPG  G  GK GP G TG PG     GP GP G PG  G PG+
Sbjct: 716  PGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPG---KDGPNGPPGPPGTKGEPGE 772

Query: 782  NGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGE 841
             G +G  G  G RG  G  GL G  GE+G  G  G  G  G  G+KG  GE G  GL G 
Sbjct: 773  RGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGL 832

Query: 842  VGDQGNIGKIGETGPVGLPGEVG-------MTGSIGEKGERGSPG--------------- 879
             GD+G  G+ G  GP GLPG          M G  G KGE+G PG               
Sbjct: 833  KGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELG 892

Query: 880  PLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGA---RGPPGSQGPKGQRGSRGPDGLLG 936
            P GP G  G  G  G  G PG  G  G PGHVGA    GPPGS G  G RG+ G DG  G
Sbjct: 893  PQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERG 952

Query: 937  EQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTG------------ 984
            E+G  G +G  G  G RG  G  G  G PG +G  G+PGL+G PG  G            
Sbjct: 953  EKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPGLPGPLGTKAACGKVR 1011

Query: 985  --------------DRGLPGEPGLRGLQGD--VGPPGEMGMEGPPGTEGESGLQGEPGAK 1028
                          DRG PG PG  G +GD  +G  G  G  GPPG +G  G +G PG  
Sbjct: 1012 GSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFP 1071

Query: 1029 GDVGTAGSVGGTGEPGLRGEPG--------APGEEGLQGKDGLKGVPGGR-GLPGEDGEK 1079
            G  G AG  G  G PG RG PG        +PG+  L  KD     P G  GLPG  G K
Sbjct: 1072 GPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFK 1131

Query: 1080 GEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKI 1139
            G+ G+PG  G  G  G+ G  GP G+ G PG  G  G +G++G  G  G+ G +G PG  
Sbjct: 1132 GDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVP 1191

Query: 1140 GKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTV 1199
            G  GP G  G  GA G  G  GP G  G PG  G  G  GPSGLPG  GE+G  G D   
Sbjct: 1192 GFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRD--- 1248

Query: 1200 LGPPGPRGEPGPVGD------QGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGE 1253
             G PGP GEPG  G+      +G RG PG +G+ G  G PG RG +G  G PG+ G  G+
Sbjct: 1249 -GKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGK 1307

Query: 1254 QGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGK 1313
             G  G  G +G +G +G PG +G PG PG  G  G  G +G  G +G  G PG +GP G 
Sbjct: 1308 DGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGP 1367

Query: 1314 QGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGA 1373
             G PG +G PG+ G+ G PG PG KG  G PG  G +GP G +G PG PGI G +GH G 
Sbjct: 1368 PGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGL 1427

Query: 1374 QGDQG------PCGDPGLKGQPGEYGVQG------------------------------- 1396
             G QG      P G PG  GQPG  G++G                               
Sbjct: 1428 MGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQM 1487

Query: 1397 ----LTGFQGFPGPKGPEGDAGIVG---------------ISGPKGPIGHRGNTGP---- 1433
                +   QG PGP GP G  G+ G               + GP GPIG +G  G     
Sbjct: 1488 PPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDP 1547

Query: 1434 ----LGREGIIGPTGRTGPRGEKGF-----------RGETGPQGPRGQPGPPGPPGAPGP 1478
                +G  G +GP G  G  GE G+           +GETGP G  G PGPPGPPG   P
Sbjct: 1548 GAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDP 1607



 Score =  719 bits (1857), Expect = 0.0
 Identities = 441/1087 (40%), Positives = 528/1087 (48%), Gaps = 212/1087 (19%)

Query: 487  LRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQP 546
            +RG  G+ G PG PG  G+ GP   +GP G+PGP G  G PGL G +G KG         
Sbjct: 549  MRGEPGELGEPGLPGEVGMRGP---QGPPGLPGPPGRVGAPGLQGERGEKG--------- 596

Query: 547  VPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPG----RQ 602
              GEKG++GL G    PG  GD G +G PG  G+ G QG  G  G  G PG PG    ++
Sbjct: 597  TRGEKGERGLDGF---PGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQE 653

Query: 603  GLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIP---GIRGKKGFKGRQGFPGDFGDR 659
            GL G +G PGP+G QG  G PG  G +GPEG  G P   G+RGKKG  G  G PG  G +
Sbjct: 654  GLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQ 713

Query: 660  GPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQ 719
            GP G  G PG  G  G PG PG  G  G  GP GP G PG  G +G  G PG KG+ GE+
Sbjct: 714  GPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGER 773

Query: 720  GTAGELGEPGY------------PGDKGAVGLPGP---PGMRGKSGPSGQTGDPGL---- 760
            G  G  G+PG             PG+KG  GLPG    PG+RG+ G  G+ G+ GL    
Sbjct: 774  GEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLK 833

Query: 761  -----QGPSGPPGPEGFPGDIGI----PGQNGPEGPKGLLGNRGPPGPPGLKGTQGE--- 808
                 +G +GP GP G PG   +    P   G +GPKG  G+ G PG PGL+G  GE   
Sbjct: 834  GDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGP 893

Query: 809  EGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGS 868
            +GP G  G  G  G  G  G AG PG  G  G  G  G  G +G  G  G PG+ G  G 
Sbjct: 894  QGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGE 953

Query: 869  IGEKGERGSPGPLGPQGEKGVMGYPGP--------------PGVPGPIGPLGLPGHV--- 911
             G  GE GSPGP+GP+G+ G  G PGP              PG+PGP+G     G V   
Sbjct: 954  KGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGS 1013

Query: 912  -----------GARGPPGSQGPKGQRGS--------RGPDGLLGEQGIQGAKGEKGDQGK 952
                       G RG PG  G  G RG          GP G  G++G  G++G  G  G 
Sbjct: 1014 ENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGP 1073

Query: 953  RGPHGLIGKTGNPGERGFQGKPGLQ---------------------------GLPGSTGD 985
            +GP G  G  GNPGERG  GKPGL                            GLPG  GD
Sbjct: 1074 QGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGD 1133

Query: 986  RGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGL 1045
            +G+PG+PG  G +G  G  G  G+ GPPG  G  G QGE GA G+VG  G  G  G PG 
Sbjct: 1134 KGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGF 1193

Query: 1046 RGEPGAP------------GEEGLQGKDGLKGVPGGR------GLPGEDGEKGEMGLPGI 1087
             G PG P            G  G+QG  G +G PG +      G+PGE+G++G  G PG 
Sbjct: 1194 MGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGP 1253

Query: 1088 IGPLGRSGQTGLPGPE------------------------GIVGIPGQRGRPGKKGDKGQ 1123
             G  G++G+ GLPGPE                        G +G+PGQ G PGK GD G 
Sbjct: 1254 PGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGP 1313

Query: 1124 IGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGY---RGHQGQPGP 1180
             GP G  G RGPPGK G  G  G  G  G  G  G  G +G PG+PG+   RG  G+PG 
Sbjct: 1314 TGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGE 1373

Query: 1181 SGLPGPKGEKGYPGED--STVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGA 1238
             G+PG +G  G PGE       G PG +G+ GP G +G+ G+PG  G+KGH G+ G +G 
Sbjct: 1374 KGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGL 1433

Query: 1239 TGQQGPPGEPGDQGEQGLKGERGSEGN--------------------------------K 1266
             G+ GP G PG  G+ G  G RG   +                                K
Sbjct: 1434 PGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMK 1493

Query: 1267 GKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRT 1326
              +G PGP G PG  GL G  GP G  G  G  G+ G  G IGP G++G  G  G PG  
Sbjct: 1494 SSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG-V 1552

Query: 1327 GLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLK 1386
            GL G  GPPG+ G    PG PG      + GLPG P         G QG+ GP G PGL 
Sbjct: 1553 GLRGEMGPPGIPGQ---PGEPGY----AKDGLPGIP---------GPQGETGPAGHPGLP 1596

Query: 1387 GQPGEYG 1393
            G PG  G
Sbjct: 1597 GPPGPPG 1603



 Score =  627 bits (1617), Expect = e-179
 Identities = 394/955 (41%), Positives = 467/955 (48%), Gaps = 165/955 (17%)

Query: 484  MEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGL------PGLPGPKGPKG 537
            ++ LRG KGD GPPG PG  G+ GP G  G  G PGP G+PGL      PG PGP GP G
Sbjct: 691  LQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTG 750

Query: 538  DPGFS-----PGQP----VPGEKGDQGL------------SGLMGPPGMQGDKGLKGHPG 576
             PG       PG P     PGE+G+ GL             GL G PG +G+ GL G PG
Sbjct: 751  PPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPG 810

Query: 577  LPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQG----FIGSPGEAGQLGPE 632
             PG+ GE+G  G  G +G PG  G +G  G  G  GP G  G    F   P   G+ GP+
Sbjct: 811  FPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPK 870

Query: 633  GERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPI 692
            GE+G PG+ G+ G +GR   PG+ G +GP G  G+ G  G  G PG  G  G+ G VG  
Sbjct: 871  GEKGDPGLPGEPGLQGR---PGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAP 927

Query: 693  GPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEP---GYPGDKGAVGLPGPPGMRGKS 749
            GP+G PG +G  G +G PG  G++GE+G AGE G P   G  GD GA GLPGPPG +GK 
Sbjct: 928  GPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKD 986

Query: 750  GPSGQTGDPGLQGPSGP-----------------------------PGPEGFPGDIGI-- 778
            G  G  G PGL GP G                              PG  G  GD GI  
Sbjct: 987  GEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGV 1046

Query: 779  ---PGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQK-------- 827
               PG +GP G KG  G+RG PG PG +G  G +G  G  GE GP GKPG          
Sbjct: 1047 AGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDI 1106

Query: 828  -------------------GYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGS 868
                               G  G  G +G+ G+ G +G  GK GE GP GLPG  G+ G 
Sbjct: 1107 NLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGP 1166

Query: 869  IGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGS 928
             G +GERG+ G +G +G++G  G PG  G PG  GP G  G  GA GPPG QG  G+ G 
Sbjct: 1167 QGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGP 1226

Query: 929  RGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGL 988
             GP G  G  GI G +G++G  GK GP G  GK G PG  G +G  G  G  G TGD G 
Sbjct: 1227 PGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGA 1286

Query: 989  PGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGE 1048
            PG    RG  G +G PG+ G+ G  G  G +G QG  G +G  G  GS G  GEPG  G 
Sbjct: 1287 PGP---RGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGT 1343

Query: 1049 PGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGI 1108
            PG  G +G  G  GL G  G RG PGE GEKG              G+ G+PG  G  G 
Sbjct: 1344 PGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGV------------PGKEGVPGKPGEPGF 1391

Query: 1109 PGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGI 1168
             G+RG PG KGDKG  G  G+ G  G PG  G +G  G +G  G  G +G  GP G+PG 
Sbjct: 1392 KGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGF 1451

Query: 1169 PGYRGHQ--------------------------GQPGPSGLPGPKGEKGYPGEDSTVLGP 1202
            PG RG                             Q  P+ +   +G  G P       GP
Sbjct: 1452 PGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPP-------GP 1504

Query: 1203 PGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGS 1262
            PG  G PG  G  GE G PG  G +G  G  G +G  G +G PG PG     GL+GE G 
Sbjct: 1505 PGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG----VGLRGEMGP 1560

Query: 1263 EGNKGKKGAPG--PSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQG 1315
             G  G+ G PG    G PGIPG QG  GP            +G+PG  GPPG  G
Sbjct: 1561 PGIPGQPGEPGYAKDGLPGIPGPQGETGP------------AGHPGLPGPPGPPG 1603



 Score =  443 bits (1140), Expect = e-124
 Identities = 279/682 (40%), Positives = 330/682 (48%), Gaps = 121/682 (17%)

Query: 489  GPKGDTGPPGPPGPAG--------------IPGP-----------------------SGK 511
            GP+GD G PG PGP G              +PGP                        G 
Sbjct: 967  GPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGD 1026

Query: 512  RGPRGIPGPHGNPGLPGL-----PGPKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQ 566
            RG  GIPG  G+ G PG+     PGP GP GD G    + +PG  G QG +G  G PG  
Sbjct: 1027 RGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNP 1086

Query: 567  GDKGLKGHPGL---------------------PGLPGEQGIPGFAGNIGSPGYPGRQGLA 605
            G++G  G PGL                     PG PG  G+PGF G+ G PG PGR+G  
Sbjct: 1087 GERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTE 1146

Query: 606  GPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLD 665
            G +G  GP G     G PG AG  G +GERG  G  G+KG +G  G PG  G  G  G  
Sbjct: 1147 GKKGEAGPPGLP---GPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPP 1203

Query: 666  GSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGEL 725
            G+ G+ G  GPPG  G  G  GP GP GP+            GLPGI G++G++G  G+ 
Sbjct: 1204 GADGIAGAAGPPGIQGSPGKEGPPGPQGPS------------GLPGIPGEEGKEGRDGKP 1251

Query: 726  GEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPE 785
            G PG PG  G  GLPGP G RG  G  G TGD G  GP G  G  G PG  G+PG++G  
Sbjct: 1252 GPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDT 1311

Query: 786  GPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQ 845
            GP G  G +GP GPPG  G+ G        GE GP G PGQKG  GE G  GL G +G +
Sbjct: 1312 GPTGPQGPQGPRGPPGKNGSPGSP------GEPGPSGTPGQKGSKGENGSPGLPGFLGPR 1365

Query: 846  GNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGP---- 901
            G  G+ GE G  G  G  G  G  G KGERG PG  G +G  G  G PG PG+PG     
Sbjct: 1366 GPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHT 1425

Query: 902  --IGPLGLPGHVGARGPPGSQGPKGQRGSRG--PDGLLGEQGIQGAKGEKGDQ------G 951
              +GP GLPG  G  GPPG  G  G  G RG  P      + IQ   G++ +        
Sbjct: 1426 GLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLA 1485

Query: 952  KRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEG 1011
            +  P  +    G PG  G  GK GL G  G  G+ G PG+ GL G  G +GP GE G +G
Sbjct: 1486 QMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKG 1545

Query: 1012 PPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRG 1071
             PG  G  GL+GE G                PG+ G+PG PG      KDGL G+PG + 
Sbjct: 1546 DPGAPG-VGLRGEMG---------------PPGIPGQPGEPG----YAKDGLPGIPGPQ- 1584

Query: 1072 LPGEDGEKGEMGLPGIIGPLGR 1093
              GE G  G  GLPG  GP G+
Sbjct: 1585 --GETGPAGHPGLPGPPGPPGQ 1604



 Score =  427 bits (1099), Expect = e-119
 Identities = 265/627 (42%), Positives = 313/627 (49%), Gaps = 88/627 (14%)

Query: 479  NTMLEMEYLRGPKGDTGPPGPPGPAGIP-----GPSGKRGPRGIPGPHGNPGLPGLPGPK 533
            N  L  + ++G +G  G PG PG  G P     GP G  GP G  G  G+ GLPG PGP+
Sbjct: 1015 NCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQ 1074

Query: 534  GPKGDPGFSPGQP-VPGEKGDQGLSGLMGPPGMQGDKGLKGH-------PGLPGLPGEQG 585
            GP G  G +PG P   G  G  GLS L+ P    GD  L          PG PGLP   G
Sbjct: 1075 GPAGRDG-APGNPGERGPPGKPGLSSLLSP----GDINLLAKDVCNDCPPGPPGLP---G 1126

Query: 586  IPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKG 645
            +PGF G+ G PG PGR+G  G +G  GP G     G PG AG  G +GERG  G  G+KG
Sbjct: 1127 LPGFKGDKGVPGKPGREGTEGKKGEAGPPGLP---GPPGIAGPQGSQGERGADGEVGQKG 1183

Query: 646  FKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSG 705
             +G  G PG  G  G  G  G+ G+ G  GPPG  G  G  GP GP GP+G+P       
Sbjct: 1184 DQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLP------- 1236

Query: 706  NKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSG 765
              G+PG +G +G  G  G  GEPG  G+ G   LPGP G RG  G  G TGD G  GP G
Sbjct: 1237 --GIPGEEGKEGRDGKPGPPGEPGKAGEPG---LPGPEGARGPPGFKGHTGDSGAPGPRG 1291

Query: 766  PPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPG 825
              G  G PG  G+PG++G  GP G  G +GP GPPG  G+ G  G      E GP G PG
Sbjct: 1292 ESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPG------EPGPSGTPG 1345

Query: 826  QKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQG 885
            QKG  GE G  GL G +G +G  G+ GE G  G  G  G  G  G KGERG PG  G +G
Sbjct: 1346 QKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKG 1405

Query: 886  EKGVMGYPGPPGVPGP------IGPLGLPGHVGARGPPGSQGPKGQRGSRG--------- 930
              G  G PG PG+PG       +GP GLPG  G  GPPG  G  G  G RG         
Sbjct: 1406 PPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLR 1465

Query: 931  -----------------------PDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGE 967
                                   P  +   QG  G  G  G  G  G  G +G+ G PG+
Sbjct: 1466 RLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQ 1525

Query: 968  RGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGA 1027
             G +G  G  G  G  G +G PG PG+ GL+G++GPPG  G  G PG   + GL G PG 
Sbjct: 1526 GGLEGPSGPIGPKGERGAKGDPGAPGV-GLRGEMGPPGIPGQPGEPG-YAKDGLPGIPGP 1583

Query: 1028 KGDVGTAGSVGGTGEPGLRGEPGAPGE 1054
            +G+ G A      G PGL G PG PG+
Sbjct: 1584 QGETGPA------GHPGLPGPPGPPGQ 1604



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 4/75 (5%)

Query: 1409 PEGDAGIVGISGPKGPIGHRGNTGPLGRE-GIIGPTGRTGPRGEKGFRGETGPQ---GPR 1464
            P G   +  ++ P  P   +    P   + G +     + P GEKG  G  GP    GP+
Sbjct: 439  PSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPK 498

Query: 1465 GQPGPPGPPGAPGPR 1479
            G  G  GP GAPGP+
Sbjct: 499  GDIGAIGPVGAPGPK 513



 Score = 32.3 bits (72), Expect = 4.1
 Identities = 26/114 (22%), Positives = 46/114 (40%), Gaps = 16/114 (14%)

Query: 160 DEQWHSFAITIRNQSVSMFVECGKKYFSTETIPEVQTFDSNSVFTLGSMNNNSIHFEGIV 219
           D  WH  A++I+ Q+VS+ ++C      T  I E +  D      +G    +S+  +  +
Sbjct: 361 DRDWHKMALSIQAQNVSLHIDCA--LVQTLPIEERENIDIQGKTVIGKRLYDSVPIDFDL 418

Query: 220 CQLDI-IPSAEASADYCRYVKQQCRQADKYQPETSIPCTTLIPTKIPEHSPPPK 272
            ++ I   S  A  + C  +              S PC   + T+ P   PP +
Sbjct: 419 QRIVIYCDSRHAELETCCDI-------------PSGPCQVTVVTEPPPPPPPQR 459


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score =  773 bits (1995), Expect = 0.0
 Identities = 498/1164 (42%), Positives = 577/1164 (49%), Gaps = 188/1164 (16%)

Query: 489  GPKGDTGPPGPPGPAGI---------PGPSGKRGPRGIPGPHGNPGLPGL----PGP-KG 534
            GP+GD G  G PG  G+         PG  G  GP+G PG  G+PG PG+    P P KG
Sbjct: 308  GPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKG 367

Query: 535  PKGDPGFSPGQPVPGEKGDQGLSGLMGPPG-----MQGDKGLKGHPGLPGLPGEQGIPGF 589
            P GDPGF       G+ G  G  GL+G PG     M G  G +G PGLPGLPGE GIPG 
Sbjct: 368  PPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGR 427

Query: 590  A----------GNIGSPGYPGRQGLAGPE------GNPGPKGAQGFIGSPG--------- 624
                       G+ G PG PG QGL G        GNPGP+G +G +G PG         
Sbjct: 428  PDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKG 487

Query: 625  -------EAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPP 677
                   E G +GP G  G+PG +G KG  G  G+ G  GD GP G +G PGL G  G  
Sbjct: 488  NEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGAS 547

Query: 678  GFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDK--- 734
            G PG +G+ G +      G  G  G  G  G PG  G  G  G AGE G+PG PGD    
Sbjct: 548  GPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDA 607

Query: 735  --GAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLG 792
              G  G PGP G  GK+GP    G PGL  P GPPG  G PG  G PG  GP+G KG  G
Sbjct: 608  TPGGKGFPGPLGPPGKAGP---VGPPGLGFP-GPPGERGHPGVPGHPGVRGPDGLKGQKG 663

Query: 793  N-----------RGPPG---PPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGL 838
            +            GPPG   PPG KG  G +G  G  G  G +G+PG  G A  PGP G 
Sbjct: 664  DTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGF 723

Query: 839  KGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSP--GPLGPQGEKGVMGYPG-- 894
            +G++GD G  G+ G + PVG PG  G  G  G+KG  G P  G LGP G++G+ G PG  
Sbjct: 724  RGDMGDPGFGGEKGSS-PVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIK 782

Query: 895  ----PPGVPGPIGPLGLPGHVGARGP---------PGSQGPKGQRGSRGPDGLLGEQGIQ 941
                 PG PG  GP G+PG +G +GP         PG  GP G    RG  G+ G+ G+ 
Sbjct: 783  GPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLP 842

Query: 942  G---------AKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEP 992
            G          KG+ GD G  GP G+ G  G PG  G  G PGL G+PG  GD GLPG P
Sbjct: 843  GYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPP 902

Query: 993  GLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKG------DVGTAGSVGGTGEPG-- 1044
            G +G +G  G PG  G  G PG EG  G +GEPG KG      D G  G+ G  G PG  
Sbjct: 903  GPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDE 962

Query: 1045 ----------LRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDG----------EKGEMGL 1084
                        GEPG PG++G  G+ G KG PG +G  GE G          E GE G 
Sbjct: 963  GEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQ 1022

Query: 1085 PGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRG----PPGKIG 1140
            PG  GP G  G TGL G  G  G+PG +G PG  G  G  G  G  G +G    P    G
Sbjct: 1023 PGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFG 1082

Query: 1141 KSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGP---SGLPGPKGEKGYPGEDS 1197
              GPKG  G+ G  GH G  G  G PGI G RG  G+PGP   SG PG  G+ G PG   
Sbjct: 1083 PPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPG--- 1139

Query: 1198 TVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGE---------- 1247
             + G PG  G+PGP G QG+ G PG  G KG  G PGL G  G +G  G           
Sbjct: 1140 -LRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVG 1198

Query: 1248 -PGDQGEQGLKGERGSEGN--------KGKKGAPGPSGKPGIPGLQGLLG---------- 1288
             PG  G  GLKGERG  G+        +GKKG PGP G  G PG  G  G          
Sbjct: 1199 PPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPG 1258

Query: 1289 PKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPG 1348
            P G QG  G DG  G PG  G PG   L  +RG PG  GL G PGPPG  G  G  G PG
Sbjct: 1259 PPGDQGPPGPDGPRGAPGPPGLPGSVDL--LRGEPGDCGLPGPPGPPGPPGPPGYKGFPG 1316

Query: 1349 IQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQG------------ 1396
              G  G++G  G PG QG  G  G  G++G  G PG KG  G  G +G            
Sbjct: 1317 CDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCP 1376

Query: 1397 -LTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFR 1455
             + G  G PG +GPEG  G+ G+ GP GP G +G  G  GR G+ G  G  GP G KG  
Sbjct: 1377 RIPGLPGAPGMRGPEGAMGLPGMRGPSGP-GCKGEPGLDGRRGVDGVPGSPGPPGRKG-- 1433

Query: 1456 GETGPQGPRGQPGPPGPPGAPGPR 1479
             +TG  G  G PGPPGP G PGP+
Sbjct: 1434 -DTGEDGYPGGPGPPGPIGDPGPK 1456



 Score =  765 bits (1975), Expect = 0.0
 Identities = 502/1252 (40%), Positives = 587/1252 (46%), Gaps = 268/1252 (21%)

Query: 488  RGPKGDTGPPGPPGPAGIPGP---------------------SGKRGPRGIPGPHGNPGL 526
            RGP G  GP GP GP G PGP                      G +GP G+PG  G  G+
Sbjct: 64   RGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGLDGI 123

Query: 527  PGLPGPKGPKGDPGF-----SPGQP-VPGEKGDQGLSGLMGPPGMQGDKGL--------- 571
            PG PGP GP+G PG      S G P  PG +G  G  G +G PG +G+KG          
Sbjct: 124  PGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFILGAVK 183

Query: 572  -----KGHPGLPGLPGE---------QGIPGFAGNIGSPGYPGRQGL------------- 604
                 +G PGLPGLPG           G PG  G +G PG PGR GL             
Sbjct: 184  GIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMG 243

Query: 605  ----AGPEGNPGP------------------KGAQGFIGSPGEAGQ-----LGPEGERGI 637
                 G +G+PGP                  KG  G +G PG  G+     +G +GE+GI
Sbjct: 244  DPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGI 303

Query: 638  PGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGP--------- 688
            PG  G +G  G  G PG  G +G  GL G PGL G  GP G PG RG  GP         
Sbjct: 304  PGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPL 363

Query: 689  --VGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTA--------GELGEPGYPGDKGAVG 738
               GP G  G PG  G +G+ G PG  G  G  G A        G  G PG PG  G  G
Sbjct: 364  PLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAG 423

Query: 739  LPG----PPGMRGKSGPSGQTGDPGLQG---------PSGPPGPEGFPGDIGIPGQNGPE 785
            +PG     PG  GK G  G  G PGLQG           G PGP+G  G +G PG  GP+
Sbjct: 424  IPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPK 483

Query: 786  GPKG-------LLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEP----- 833
            G KG         G  GPPGPPGL G QG +G +G  G LG +G PG  G  G P     
Sbjct: 484  GEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGK 543

Query: 834  ----GPEGLKGEVGD------QGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGP 883
                GP G KG  GD      +G+ G+ G  GP G PG+ G  G  G  GE+G PGP G 
Sbjct: 544  HGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGD 603

Query: 884  Q-----GEKGVMGYPGPPGVPGPIGPLGL--------------PGHVGARGP-------- 916
                  G KG  G  GPPG  GP+GP GL              PGH G RGP        
Sbjct: 604  HEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKG 663

Query: 917  ---------PGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGE 967
                     PG  GP G  G  GP G  G QG  G  G  G +G+ G  G     G PG 
Sbjct: 664  DTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGF 723

Query: 968  RGFQGKPGLQGLPGST--GDRGLPGEPGLRGLQ--------GDVGPPGEMGMEGPPGTEG 1017
            RG  G PG  G  GS+  G  G PG PG+ G +        G +GPPG+ G+ G PG +G
Sbjct: 724  RGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKG 783

Query: 1018 ESGLQGEPGAKGDVGTAGSV---------GGTGEPGL---------RGEPGAPGEEGLQG 1059
              G  G PGA+G  G  G +         G  G PG+         RG PG PG+ GL G
Sbjct: 784  PRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPG 843

Query: 1060 KDGLKGVPGGR------------------GLPGEDGEKGEMGLPGIIGPLGRSGQTGLPG 1101
              G  G PGG+                  GLPG  G  G  GLPGI GP G  G  G PG
Sbjct: 844  YPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPG 903

Query: 1102 PEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMG 1161
            P+G  G+P   G PG  G++G+ G  G  G++G PG+ G SG  G RG RGA G +G  G
Sbjct: 904  PKGPRGLP---GFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPG 960

Query: 1162 PDGEPGIPGYRGHQGQPGP---SGLPGPKGEKGYPG-----EDSTVLGPPG-PRGEPGPV 1212
             +GE  I   +G  G+PGP    G PG +G+KG PG      +    GPPG  RGEPG  
Sbjct: 961  DEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEK 1020

Query: 1213 GDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKK--- 1269
            G  G  G PG  G  G  G  G  G  G QG PG PG  G  G+ G RG +GNKG     
Sbjct: 1021 GQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASH 1080

Query: 1270 -GAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGL 1328
             G PGP G+PG PG  G  G  G QG  G  G  G+PG+ GPPG  G PG  G  G  GL
Sbjct: 1081 FGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGL 1140

Query: 1329 AGA------PGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQ-----GDQ 1377
             G       PGP G++G  G+PG PGI+GP G  GL G  G++G++G +GA      G  
Sbjct: 1141 RGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPP 1200

Query: 1378 GPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRG-------N 1430
            GP G PGLKG+ G+ G  G++     PGP+G +G  G  G SGP GP G  G       +
Sbjct: 1201 GPVGIPGLKGERGDPGSPGISP----PGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPD 1256

Query: 1431 TGPLGREGIIGPTGRTGPRGEKGFRGET----GPQGPRGQPGPPGPPGAPGP 1478
             GP G +G  GP G  G  G  G  G      G  G  G PGPPGPPG PGP
Sbjct: 1257 PGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGP 1308



 Score =  731 bits (1887), Expect = 0.0
 Identities = 467/1122 (41%), Positives = 552/1122 (49%), Gaps = 174/1122 (15%)

Query: 488  RGPKGDTGPPGPPGPAGIPGPSGKRGPRGIP------GPHGNPGLP------------GL 529
            +G KG TG PG PG  GIPG  G  GPRG P      G  G+PG P            G 
Sbjct: 106  KGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGH 165

Query: 530  PGPKGPKGDPGFSPG--QPVPGEKGDQGLSGL---------MGPPGMQGDKGLKGHPGLP 578
            PG KG KG+  F  G  + + G++GD GL GL          GP G  G+ GL G PG P
Sbjct: 166  PGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQP 225

Query: 579  GLPGEQGIPGFA--GNIGSPGYPGRQGLAGP------------EGNPGPKGAQGFIGSPG 624
            G PG +G PG    G +G PG  G+QG  GP            +G  G KG  G +G PG
Sbjct: 226  GRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPG 285

Query: 625  EAGQ-----LGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGF 679
              G+     +G +GE+GIPG  G +G  G  G PG  G +G  GL G PGL G  GP G 
Sbjct: 286  PPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGD 345

Query: 680  PGLRGSVGPVG-----------PIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTA------ 722
            PG RG  GP G           P G  G PG  G +G+ G PG  G  G  G A      
Sbjct: 346  PGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIG 405

Query: 723  --GELGEPGYPGDKGAVGLPG----PPGMRGKSGPSGQTGDPGLQGPSGP---------P 767
              G  G PG PG  G  G+PG     PG  GK G  G  G PGLQG  G          P
Sbjct: 406  PPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNP 465

Query: 768  GPEGFPGDIGIPGQNGPEGPKGLLG-------NRGPPGPPGLKGTQGEEGPIGAFGELGP 820
            GP+G  G +G PG  GP+G KG  G         GPPGPPGL G QG +G +G  G LG 
Sbjct: 466  GPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGT 525

Query: 821  RGKPGQKGYAGEPG---------PEGLKGEVGD------QGNIGKIGETGPVGLPGEVGM 865
            +G PG  G  G PG         P G KG  GD      +G+ G+ G  GP G PG+ G 
Sbjct: 526  KGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGS 585

Query: 866  TGSIGEKGERGSPGPLGPQGEK--GVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPK 923
             G  G  GE+G PGP G   +   G  G+PGP G PG  GP+G PG +G  GPPG +G  
Sbjct: 586  HGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPG-LGFPGPPGERGHP 644

Query: 924  G---QRGSRGPDGLLGEQG--------IQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQG 972
            G     G RGPDGL G++G          G  G  G  G  GP G  G  G PG     G
Sbjct: 645  GVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPG---LSG 701

Query: 973  KPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGME--GPPGTEGESGLQGEPGAKGD 1030
              G +G PG+ G   +PG PG RG  GD G  GE G    GPPG  G  G+ G+ G  GD
Sbjct: 702  SDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGD 761

Query: 1031 -----VGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLP 1085
                 +G  G  G +G PG++G  G PG     G +G  G+PG  GL G  G +G  G P
Sbjct: 762  PAFGHLGPPGKRGLSGVPGIKGPRGDPG---CPGAEGPAGIPGFLGLKGPKGREGHAGFP 818

Query: 1086 GIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPK 1145
            G+ GP G S + G PG  G  G+PG  G PG  G KGQ            PG +G  GP 
Sbjct: 819  GVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQ------------PGDVGPPGPA 866

Query: 1146 GARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGP 1205
            G +G  G  G  G  GP G PGIPG  G  G PGP G  GP+G  G+PG        PG 
Sbjct: 867  GMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGF-------PGE 919

Query: 1206 RGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGN 1265
            RG+PG  G  G +GEPG +G  G  G  GLRGA G  GPPG   D+GE  +  ++G+ G 
Sbjct: 920  RGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPG---DEGEMAIISQKGTPGE 976

Query: 1266 KGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPG-KQGLPGIRGGPG 1324
                  PGP G  G PG +G  G  G+QG  G       PG+ GPPG  +G PG +G PG
Sbjct: 977  ------PGPPGDDGFPGERGDKGTPGMQGRRG------EPGRYGPPGFHRGEPGEKGQPG 1024

Query: 1325 RTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGP-CGDP 1383
              G  G PG  G++G  G PG PG QG  G  G PG  GI G RG +G +GD     G P
Sbjct: 1025 PPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPP 1084

Query: 1384 GLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPT 1443
            G KG+PG           G PG  G  G+ G+ GI GP+G  G  G  G  G  G  G  
Sbjct: 1085 GPKGEPGS---------PGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDH 1135

Query: 1444 GRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQMDIN 1485
            G  G RG+ G  G+ GP+G +G PG PGPPG  GP     +N
Sbjct: 1136 GMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLN 1177



 Score =  730 bits (1885), Expect = 0.0
 Identities = 491/1205 (40%), Positives = 564/1205 (46%), Gaps = 262/1205 (21%)

Query: 510  GKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDK 569
            G RGP G PGP          GP GP G PG     P+ G  G++G+ G  GPPG  GDK
Sbjct: 62   GSRGPPGPPGPQ---------GPIGPLGAPG-----PI-GLSGEKGMRGDRGPPGAAGDK 106

Query: 570  GLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQL 629
            G KG  G+PG PG  GIPG  G  G  G PG  G  G  G+PG  G +G +G  G  G  
Sbjct: 107  GDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHP 166

Query: 630  GPEGERG--------IPGIRGKKGFKGRQGFPGDFGDRGPA---GLDGSPGLVGGTGPPG 678
            G +GE+G        + GI+G +G  G  G PG +G  GPA   G  G PGLVG  G PG
Sbjct: 167  GEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPG 226

Query: 679  FPGLRGS--------VGPVGPIGPAGIPGP------------------MGLSGNKGLPGI 712
             PGL+G+        +G  G +G  G PGP                   G+ G  GLPG 
Sbjct: 227  RPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGP 286

Query: 713  KGDKGE-----------------QGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQT 755
             G KGE                 +G  G  G PG+PG KG +GL G PG+ G  GP G  
Sbjct: 287  PGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDP 346

Query: 756  GDPGLQGP-----------SGPPGPEGFPGDIGIPGQNGPEGPKGLLGNR--------GP 796
            G+ G  GP            GPPG  GFPG  G  G  GP GP GLLG          GP
Sbjct: 347  GNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGP 406

Query: 797  PGPPGLKGTQGEEGPIGAFGEL-GPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETG 855
            PGP G  G  G  G  G  G      GKPG+ G  G PG  GL+G  G       +G  G
Sbjct: 407  PGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPG 466

Query: 856  PVGLPGEVGMTGSIGEKGERGS-------PGPLGP---------QGEKGVMGYP------ 893
            P G+ G+VG  G  G KGE+G+       PGP+GP         QG KG +G P      
Sbjct: 467  PQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTK 526

Query: 894  GPPGVPGPIGPLGLPGHVGARGPPGSQGP---------KGQRGSRGPD------GLLGEQ 938
            G PG PG  GP GLPG  GA GPPG++G          KG +G RGPD      G  G  
Sbjct: 527  GDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSH 586

Query: 939  GIQGAKGEKGDQGKRGPH--------GLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPG 990
            G  G  GEKGD G  G H        G  G  G PG+ G  G PGL G PG  G+RG PG
Sbjct: 587  GRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGL-GFPGPPGERGHPG 645

Query: 991  EP---------GLRGLQGDV-----------GPPGEMGMEGP---PGTEGESGLQGEPGA 1027
             P         GL+G +GD            GPPG  G  GP   PG +G  GL G  G 
Sbjct: 646  VPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGH 705

Query: 1028 KGDVGTAGSVGGTGEPGLRGE-----------------PGAPGEEGLQGKDGLK------ 1064
            KG  GT G+    G PG RG+                 PG PG  G+ G+ G+       
Sbjct: 706  KGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFG 765

Query: 1065 --GVPGGRGL---PGEDGEKGEMGLPGIIGPLGRSGQTGLPGPE------GIVGIPGQRG 1113
              G PG RGL   PG  G +G+ G PG  GP G  G  GL GP+      G  G+PG  G
Sbjct: 766  HLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPG 825

Query: 1114 R---------PGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDG 1164
                      PG+ G  G  G  G  G +G PG +G  GP G +G  G  G  G  GP G
Sbjct: 826  HSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPG 885

Query: 1165 EPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAE 1224
             PGIPG  G  G PGP   PGPKG +G PG      G PG RG+PG  G  G +GEPG +
Sbjct: 886  LPGIPGPFGDDGLPGP---PGPKGPRGLPG----FPGFPGERGKPGAEGCPGAKGEPGEK 938

Query: 1225 GYKGHVGVPGLRGATG---------------QQGPPGEPGDQGEQGLKGERGSE------ 1263
            G  G  G  GLRGA G               Q+G PGEPG  G+ G  GERG +      
Sbjct: 939  GMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQ 998

Query: 1264 ----------------GNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGK 1307
                            G  G+KG PGP G PG PG  GL   +G  G+ G  G  G PG 
Sbjct: 999  GRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGL---RGFIGFPGLPGDQGEPGS 1055

Query: 1308 IGPPGKQGLPGIRGGPGRTG-LAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQG 1366
             GPPG  G+ G RG  G  G  A   GPPG KG  G PG PG  G  GEQGLPG  G +G
Sbjct: 1056 PGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRG 1115

Query: 1367 KRGHRGAQGDQGP--C----GDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISG 1420
              G  G  G  GP  C    G PGL+GQPGE G  G  G QG PG  GP G  G  G  G
Sbjct: 1116 SPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPG 1175

Query: 1421 PKGPIGHRGNTGPLGREGI--IGPTGRTGPRGEKGFRGETG-----PQGPRGQPGPPGPP 1473
              G  G +G  G  G  G+  +GP G  G  G KG RG+ G     P GPRG+ GPPGPP
Sbjct: 1176 LNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPP 1235

Query: 1474 GAPGP 1478
            G+ GP
Sbjct: 1236 GSSGP 1240



 Score =  699 bits (1805), Expect = 0.0
 Identities = 448/1007 (44%), Positives = 522/1007 (51%), Gaps = 74/1007 (7%)

Query: 534  GPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGI------P 587
            GP G    S    VP EKG +G  G   PPG QG  G  G PG  GL GE+G+      P
Sbjct: 45   GPCGGRDCSVCHCVP-EKGSRGPPG---PPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPP 100

Query: 588  GFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFK 647
            G AG+ G  G  G  G  G +G PG  G  G  G PG +G  G  G+ G PG RG  G  
Sbjct: 101  GAAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPG 160

Query: 648  GRQGFPGDFGDRGPAG--LDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSG 705
            G  G PG+ G++G +   L    G+ G  G PG PGL GS G  GP GP G PG  GL G
Sbjct: 161  GPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVG 220

Query: 706  NKGLPGIKGDKGEQGTA--GELGEPGYPGDKGAVG---LPGPPGMRGKSGPSGQTGDPGL 760
              G PG  G KG  G    G++G+PG  G +G+ G   L  PP      G  G  G PG+
Sbjct: 221  PPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGM 280

Query: 761  QGPSGPPGPEGFPGDIGIPGQNGP---EGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGE 817
             G  GPPG +G  G IG  G+ G     GP+G  G+ G PG PGLKG  G  G  G FG 
Sbjct: 281  VGLPGPPGRKGESG-IGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGL 339

Query: 818  LGPRGKPGQKGYAGEPG-----PEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEK 872
            +GP+G PG +G+ G PG     P  LKG  GD G  G+ GETG VG PG  G+ G  GE 
Sbjct: 340  IGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGE- 398

Query: 873  GERGSPGPLGPQGEKGVMGYPGPPGVPG-PIGPLGLPGHVGARGPPGSQGPKGQRGSRGP 931
               G  GP GPQG  G+ G PG  G+PG P    G PG  G+ G PG+ G +G  GS   
Sbjct: 399  ACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVI 458

Query: 932  DGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTG----NPGERGFQGKPGLQGLPGSTGDRG 987
               +G  G QG KG+ G  G RGP G  G  G     PG  G  G PGL G  GS GD G
Sbjct: 459  YCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLG 518

Query: 988  LPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRG 1047
            L   PG  G +GD GPPG  G  G PG  G SG  G  GAKGD+  +   G  GE G  G
Sbjct: 519  L---PGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDG 575

Query: 1048 EPGAPGEEGLQGKDGLKGVPGGRGLPG--EDGEKGEMGLPGIIGPLGRSGQTGLPGPEGI 1105
             PG PG+ G  G+DG  G  G  G PG  ED   G  G PG +GP G++G  G PG  G 
Sbjct: 576  PPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPG-LGF 634

Query: 1106 VGIPGQRGRPGKKGDKGQIGPTGEVGSR--------------GPPGKIGKSGPKGARGTR 1151
             G PG+RG PG  G  G  GP G  G +              GPPG  G  GPKG  G +
Sbjct: 635  PGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQ 694

Query: 1152 GAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGE-DSTVLGPPGPRGEPG 1210
            GA    GL G DG  G PG  G    PGP G  G  G+ G+ GE  S+ +GPPGP G PG
Sbjct: 695  GAP---GLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPG 751

Query: 1211 PVGDQGERGEP-----GAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQ---GLKGERGS 1262
              G +G  G+P     G  G +G  GVPG++G  G  G PG  G  G     GLKG +G 
Sbjct: 752  VNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGR 811

Query: 1263 EGNKGKKGAPGPSG---KPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGI 1319
            EG+ G  G PGP G   + G PG+ G  G  G  G  GA G  G PG +GPPG  G+ G+
Sbjct: 812  EGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGL 871

Query: 1320 RGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGP 1379
             G PGR G  G PG PG+ G  G  G PG  GPKG +GLPG PG  G+RG  GA+G  G 
Sbjct: 872  PGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGA 931

Query: 1380 CGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIV------GISGPKGPIGHRGNTGP 1433
             G+PG KG  G  G +GL G +G  GP G EG+  I+      G  GP G  G  G  G 
Sbjct: 932  KGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGD 991

Query: 1434 LGREGIIGPTGRTGPRGEKGF-RGETGPQGPRGQPGPPGPPGAPGPR 1479
             G  G+ G  G  G  G  GF RGE G +G  G PGPPGPPG+ G R
Sbjct: 992  KGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLR 1038



 Score =  679 bits (1752), Expect = 0.0
 Identities = 451/1113 (40%), Positives = 521/1113 (46%), Gaps = 235/1113 (21%)

Query: 489  GPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQP-- 546
            G  GD GPPGPPG  G PG +   G  G PGP G PGLPGLPG  G  G P  +PG+P  
Sbjct: 379  GETGDVGPPGPPGLLGRPGEACA-GMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGK 437

Query: 547  --------------VPGEK---------GDQGLSGLMGPPGMQGDKGLKGHPGL----PG 579
                          +PG           G QG+ G +GPPG +G KG KG+ GL    PG
Sbjct: 438  PGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPG 497

Query: 580  LPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPG 639
              G  G PG  G  GS G  G  G  G +G+PGP GA+G  G PG+ G  GP G +G  G
Sbjct: 498  PMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKG 557

Query: 640  ------IRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPG-----------FPGL 682
                  ++G KG +G  G PG  G  G  G DG  G  G  GPPG           FPG 
Sbjct: 558  DMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGP 617

Query: 683  RGSVGPVGPIGPAGI--PGPMGLSGNKGLPGIKGDKGEQGTAGELGE------------- 727
             G  G  GP+GP G+  PGP G  G+ G+PG  G +G  G  G+ G+             
Sbjct: 618  LGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHG 677

Query: 728  -PGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEG 786
             PG+ G  G  G PGP G  G SG  G  G PG  G +  PGP GF GD+G PG  G +G
Sbjct: 678  PPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKG 737

Query: 787  PKGLLGNRGPPGPPGLKGTQGEEGPIG--AFGELGPRGK------------------PGQ 826
               +    GPPGPPG  G  G++G  G  AFG LGP GK                  PG 
Sbjct: 738  SSPV----GPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGA 793

Query: 827  KGYAGEPGPEGLKGEVGDQGNIGKIGETGPVG---------------LPGEVGMTGSIGE 871
            +G AG PG  GLKG  G +G+ G  G  GP G               LPG  G  G+ G 
Sbjct: 794  EGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGG 853

Query: 872  KGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGP 931
            KG+ G  GP GP G KG+ G PG PG  GP G  G+PG  G  G PG  GPKG RG  G 
Sbjct: 854  KGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGF 913

Query: 932  DGLLGE------QGIQGAKGEKG---------DQGKRGPHGLIGKTGNPGER-------- 968
             G  GE      +G  GAKGE G         D+G RG  G IG  G+ GE         
Sbjct: 914  PGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGT 973

Query: 969  -GFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGA 1027
             G  G PG  G PG  GD+G PG  G RG  G  GPPG     G PG +G+ G  G PG 
Sbjct: 974  PGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFH--RGEPGEKGQPGPPGPPGP 1031

Query: 1028 KGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGL-------------------KGVPG 1068
             G  G  G +G  G PG +GEPG+PG  G  G DG                    KG PG
Sbjct: 1032 PGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPG 1091

Query: 1069 GRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQ------RGRPGKKGDKG 1122
              G PG  G  GE GLPGI GP G  G+ G PG  G  G PG       RG+PG+ GD G
Sbjct: 1092 SPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPG 1151

Query: 1123 QIGPTGEVGSRGPPGKIGKSGP---------KGARGTRGAVGHLGLMGPDGEPGIPGYRG 1173
              G  G+ G  GPPG  G SG          KG +GT+GA G L  +GP G  GIPG +G
Sbjct: 1152 PRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASG-LHDVGPPGPVGIPGLKG 1210

Query: 1174 HQGQPGPSGL--PGPKGEKGYPGEDSTVLGPPGPRG----------EPGPVGDQGE---- 1217
             +G PG  G+  PGP+G+KG PG   +  GPPGP G          +PGP GDQG     
Sbjct: 1211 ERGDPGSPGISPPGPRGKKGPPGPPGSS-GPPGPAGATGRAPKDIPDPGPPGDQGPPGPD 1269

Query: 1218 ------------------RGEPG------------AEGYKGHVGVPGLRGATGQQGPPGE 1247
                              RGEPG              G  G+ G PG  G  GQ+GP G 
Sbjct: 1270 GPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGF 1329

Query: 1248 PGDQGEQGL------KGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGI 1301
            PG QG  G       KG  G  G KG  G PGP G+PG         P  +       G+
Sbjct: 1330 PGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPG--------PPADVDDCPRIPGL 1381

Query: 1302 SGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQ 1361
             G PG  GP G  GLPG+RG          P  PG KG  GL G  G+ G  G  G PG+
Sbjct: 1382 PGAPGMRGPEGAMGLPGMRG----------PSGPGCKGEPGLDGRRGVDGVPGSPGPPGR 1431

Query: 1362 PGIQGKRGHRGAQGDQGPCGDPGLKG-QPGEYG 1393
             G  G+ G+ G  G  GP GDPG KG  PG  G
Sbjct: 1432 KGDTGEDGYPGGPGPPGPIGDPGPKGFGPGYLG 1464



 Score =  455 bits (1170), Expect = e-127
 Identities = 303/707 (42%), Positives = 349/707 (49%), Gaps = 130/707 (18%)

Query: 869  IGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGS 928
            + EKG RG PGP GPQ               GPIGPLG P      GP G  G KG RG 
Sbjct: 58   VPEKGSRGPPGPPGPQ---------------GPIGPLGAP------GPIGLSGEKGMRGD 96

Query: 929  RGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGL 988
            RGP G  G+      KG+KG  G  G  GL G  G+PG  G +GKPG+ G  GS GD G 
Sbjct: 97   RGPPGAAGD------KGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGF 150

Query: 989  PGEPGLRGLQGDVGPPGEMG-----------MEGPPGTEGESGLQGEPGAKGDVGTAGSV 1037
            PG  G  G  G +G PGE G           ++G  G  G+ GL G PG+ G  G AG  
Sbjct: 151  PGGRGALGPGGPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPT 210

Query: 1038 GGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGE---------------------D 1076
            G  GEPGL G PG PG  GL+G  G+ GV G  G PGE                      
Sbjct: 211  GYPGEPGLVGPPGQPGRPGLKGNPGV-GVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYK 269

Query: 1077 GEKGEMGLPGII---GPLGRSGQTGL--PGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVG 1131
            GEKG  G+PG++   GP GR G++G+   G +GI G PG RG PG  G  G  G  GE+G
Sbjct: 270  GEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELG 329

Query: 1132 SRGPPGKIGKSGPKGARGTRGAVGHLG--------LMGPDGEPGIPGYRGHQGQPGPSGL 1183
              G PG  G  GPKG  G RG  G  G        L GP G+PG PG  G  G  GP   
Sbjct: 330  LVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGP--- 386

Query: 1184 PGPKGEKGYPGED-STVLGPPGPRGEPGPVGDQGERGEPG----AEGYKGHVGVPGLRGA 1238
            PGP G  G PGE  + ++GPPGP+G PG  G  GE G PG    A G  G  G PGL GA
Sbjct: 387  PGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGA 446

Query: 1239 TGQQGPPGEP------GDQGEQGLKGERGSEGNKGKKG----------APGPSGKPGIPG 1282
             G QG PG        G+ G QG+KG+ G  G +G KG           PGP G PG PG
Sbjct: 447  PGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPG 506

Query: 1283 LQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGS-- 1340
            L G  G KG  G  G  G  G+P   GPPG +G PG+   PG+ G +G PG  G KG   
Sbjct: 507  LPGRQGSKGDLGLPGWLGTKGDP---GPPGAEGPPGL---PGKHGASGPPGNKGAKGDMV 560

Query: 1341 -SGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGD-----PGLKGQPGEYGV 1394
             S + G  G +GP G  G PGQPG  G+ GH G +GD GP GD     PG KG PG  G 
Sbjct: 561  VSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGP 620

Query: 1395 QGLTG-----FQGFPGPKGPEGDAGI---VGISGPKGPIGHRGNT-----------GPLG 1435
             G  G       GFPGP G  G  G+    G+ GP G  G +G+T           GP G
Sbjct: 621  PGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPG 680

Query: 1436 REGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQM 1482
             +G  GP G  GP+G  G  G  G +G  G PG    PG PG R  M
Sbjct: 681  FDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDM 727



 Score =  145 bits (367), Expect = 3e-34
 Identities = 85/196 (43%), Positives = 102/196 (52%), Gaps = 20/196 (10%)

Query: 484  MEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSP 543
            ++ LRG  GD G PGPPGP G PGP G +G  G  G  G  G  G PGP+GP G PG   
Sbjct: 1284 VDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPG--- 1340

Query: 544  GQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPG----LPGLPGEQGIPGFAGNIGSPGYP 599
                PGEKG  G  G  GP G+ G +G  G P      P +PG  G PG  G  G+ G P
Sbjct: 1341 ---PPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLP 1397

Query: 600  GRQGLAGP--EGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFG 657
            G +G +GP  +G PG  G +G  G PG  G  G +G+       G+ G+ G  G PG  G
Sbjct: 1398 GMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGD------TGEDGYPGGPGPPGPIG 1451

Query: 658  DRGPAGLDGSPGLVGG 673
            D GP G    PG +GG
Sbjct: 1452 DPGPKGF--GPGYLGG 1465


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
            sapiens]
          Length = 1424

 Score =  767 bits (1981), Expect = 0.0
 Identities = 499/1206 (41%), Positives = 582/1206 (48%), Gaps = 239/1206 (19%)

Query: 491  KGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGE 550
            KGD G PG PGP G+PGP G  GP G PGP G  G PG  GP+GPKG  G    + V G 
Sbjct: 170  KGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMG----ERVIGH 225

Query: 551  KGDQGLSGLMGPPG-----------------MQGDKGLKGHPGLPGLPGEQGIPG--FAG 591
            KG++G+ GL GPPG                 ++G+KG KG  G PG PG  G+PG  +  
Sbjct: 226  KGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGS 285

Query: 592  NIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQG 651
              G+PG PG QG  G +G PG  G++G             +G RG PG+ G+ G KG++G
Sbjct: 286  EKGAPGDPGLQGKPGKDGVPGFPGSEGV------------KGNRGFPGLMGEDGIKGQKG 333

Query: 652  FPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMG-----LSGN 706
              G  G RGP     +    G  G PG PG RG+ GP GP GP G+PG  G     L G 
Sbjct: 334  DIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGA 393

Query: 707  KGLPGIKGDKGEQGTAGE--LGEPGYPGDKGAVGLPG----------------PPGMRGK 748
             G PG+KG KGE+G  G+  +G PG PG  G+ GLPG                PPG  G 
Sbjct: 394  PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGL 453

Query: 749  SGPSGQTGDPGLQGPSG--------------PPGPEGFPGDIGIPGQNGPEGPKGLLGNR 794
             G  G  G PG+ GP G              PPG  G PG  G+ G  G +G  GL G+ 
Sbjct: 454  PGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSP 513

Query: 795  GPPG---------------PPGLKGTQGE----EGPIGAFGELGPRGKPGQKGYAGEPGP 835
            G PG                PGLKG +GE    EG +G  G+ G RG+PG+KG  G PG 
Sbjct: 514  GSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGT 573

Query: 836  EGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGE------KGV 889
             G+KG  G +G +   GE G  G PG+ G  GS G  G  G PG  GPQGE      +GV
Sbjct: 574  PGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGTQGV 632

Query: 890  MGYPGPPG-------------VPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRG------ 930
             G PGPPG             VPGP GP G PGH G +GPPG  G  G+ G  G      
Sbjct: 633  PGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDG 692

Query: 931  -----------PDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPG------------- 966
                       P G  G+QG  G KG  G  GK G  GL GK G PG             
Sbjct: 693  EPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP 752

Query: 967  -------ERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGT--EG 1017
                   ERG  G+ G  GLPG  G  G PG  GL G +GD G PG  G +GPPG   EG
Sbjct: 753  GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812

Query: 1018 ESGLQGEPGA---KGDVGTAGSVGGTGEPGL-----------RGEPGAPGEEGLQGKDGL 1063
              G QG PG    KG  G  G  G  G+PG+            G PG PG +G  G  G 
Sbjct: 813  PRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ 872

Query: 1064 KGVPGGRGL---PGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPG---QRGRPGK 1117
            +G PG  G+   PGEDG  G MG PG IGP G  G  G PG  G  GIPG   QRG PG 
Sbjct: 873  RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932

Query: 1118 KG---DKGQIGPT---------------------GEVGSRGPPGKIGKSGPKGARGTRGA 1153
            KG   DKG  GP+                     GE G+RG PG  G  G KG  G  G 
Sbjct: 933  KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992

Query: 1154 VGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKG---YPGE--------------- 1195
             G  G +G  G PG PG RG  G  G  G+PG KG++G   +PG                
Sbjct: 993  PGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGD 1052

Query: 1196 -------DSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEP 1248
                   + T  GPPGP G+PG  GD G++GE G  G  GH+G  G  GA G  G PG P
Sbjct: 1053 KGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLP 1112

Query: 1249 GDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKI 1308
            G  G  G   + G +G KG  G PG  G PG+PG  G  GP GI+G  G DGI G  G+ 
Sbjct: 1113 GKPGPHG---DLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEK 1169

Query: 1309 G-------PPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQ 1361
            G       PPG +G PG +G  G  G   APG PG+ G  G  G  G +GP G +G PG 
Sbjct: 1170 GETGLLRAPPGPRGNPGAQGAKGDRG---APGFPGLPGRKGAMGDAGPRGPTGIEGFPGP 1226

Query: 1362 PG-----IQGKRGHRGAQGDQGPCGDPGLKGQPGEY--GVQGLTGFQGFPGPKGPEGDAG 1414
            PG     I G+ G+RG  G +G  G PG  G PG +  G++G  G  G PGPKGP G AG
Sbjct: 1227 PGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286

Query: 1415 IVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPG 1474
             +G  G  G  G  G  GP G  G  G  G  G +G  GF G  GP GP G  GPPG  G
Sbjct: 1287 DMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRG 1346

Query: 1475 APGPRK 1480
             PG  K
Sbjct: 1347 DPGTLK 1352



 Score =  754 bits (1946), Expect = 0.0
 Identities = 509/1309 (38%), Positives = 597/1309 (45%), Gaps = 329/1309 (25%)

Query: 489  GPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGD------PGFS 542
            G KG+ G  G PGP G PG  G  GP G+PGP G  G PGLPG  G KG       PGFS
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 543  PGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFA------------ 590
                +PG  G+ G  GL+G PG  G KG +G PGLPG  G  GIPG A            
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 591  --------GNIGSPGYPGRQGLAGPEGNP---GPKGAQGFIGSPGEAGQLGP-------- 631
                    G+ G PG PG QGL GP G P   GP G  GF G PG  G  GP        
Sbjct: 163  EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERV 222

Query: 632  ---EGERGIPGIRGKKG-----------------FKGRQGFPGDFGDRGPAGLDGSPGLV 671
               +GERG+ G+ G  G                  KG +G  G  G+ GP G  G PG  
Sbjct: 223  IGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGES 282

Query: 672  GGT--GPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPG 729
             G+  G PG PGL+G     G  G  G PG  G+ GN+G PG+ G+ G +G  G++G PG
Sbjct: 283  YGSEKGAPGDPGLQGK---PGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPG 339

Query: 730  YPG---------DKGAVGLPGPPGMRGKSGPSGQTGDPGLQGP----------------- 763
            + G         +KG  G PGPPG RG  GP G +G PG+ G                  
Sbjct: 340  FRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGL 399

Query: 764  -----------------------------SGPPGPEGFPGDI------------------ 776
                                          G PGP G PGDI                  
Sbjct: 400  KGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGS 459

Query: 777  -GIPGQNGPEGPKGLLGNR-----GPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYA 830
             GIPG +GP+G  GLL  +     GPPG PGL G  G +G  G  G  G +G PG  G  
Sbjct: 460  PGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNT 519

Query: 831  GEPGPEGLKGEVGDQGNIGKIGET----GPVGLPGEVGMTGSIGEK-------------- 872
            G PG  G  G  GD G  G+ GET    G VG+PG+ G+ G  G K              
Sbjct: 520  GLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGL 579

Query: 873  ----------------------GERGSPGPLGP--------------QGEKGVMGYPGPP 896
                                  G  GSPGP GP              QG +GV G PGPP
Sbjct: 580  PGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPP 639

Query: 897  G-------------VPGPIGPLGLPGHVGARGP---PGSQGPKGQRGSRGPDGLLGEQGI 940
            G             VPGP GP G PGH G +GP   PGS G  G  G  GPDG  G  GI
Sbjct: 640  GEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI 699

Query: 941  --QGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQG--------LPGSTGDRGLPG 990
               G  G KGDQG  G  G +G  G  GE G  GKPGL G        +PG  G  G PG
Sbjct: 700  GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 991  EPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSV--------GGTGE 1042
            E G  G  G++G PG  G+ G PG EG  G +G+PG  G  G  G          G  G 
Sbjct: 760  ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819

Query: 1043 PGL---------------RGEPGAPG--EEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLP 1085
            PGL               +G+PG PG    G  G+ G  G+PG +G  G  G++G  G P
Sbjct: 820  PGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNP 879

Query: 1086 GIIGPLGRSGQTGL---------PGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPP 1136
            GI+GP G  G  G+         PGP G  G PGQRG PG  G KGQ G  G  G +G  
Sbjct: 880  GILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDK 939

Query: 1137 GKIGKS------GPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEK 1190
            G  G S      G KG  G +G  G+ G  G  G PG+PG +G +G PGP+G PGP+G+ 
Sbjct: 940  GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999

Query: 1191 GYPGEDSTVLGPPGPRGEPGPVGDQ---GERGEPGAEGYKGHVGVPGLRGATGQQGP--- 1244
            G  G      G PG RG PG +G+    G +G+ G  G+ G  G PGL G  G QG    
Sbjct: 1000 GSTGNP----GEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE 1055

Query: 1245 --------PGEPGDQGEQGLKGERGSEGNKGKKGAP---------GPSGKPGIPGLQGLL 1287
                    PG PG  G+ GL G+ G +G  G+ G P         G  G PG PGL G  
Sbjct: 1056 PGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKP 1115

Query: 1288 GPKGIQGYHGADGISGNPGKIGPPGKQGLP------GIRGGPGRTGLAGAPGPPGVKGSS 1341
            GP G  G+ G  G+ G PG  GPPG  G P      GIRG  GR G+   PGP G KG +
Sbjct: 1116 GPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGI---PGPAGEKGET 1172

Query: 1342 GL-------PGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPC------GDPGL--- 1385
            GL        G+PG QG KG++G PG PG+ G++G  G  G +GP       G PGL   
Sbjct: 1173 GLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGA 1232

Query: 1386 --KGQPGEYGVQGLTGFQGFPGPKGP--------EGDAGIVGISGPKGPIGHRGNTGPLG 1435
               GQ G  G  G  G  G PGP GP        +GD G +G  GPKGP G  G+ GP G
Sbjct: 1233 IIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPG 1292

Query: 1436 REGIIGPTGRTGPRGEKGFRGETGPQGPRGQP------GPPGPPGAPGP 1478
            R G  G  G  GPRG+ GF+G  G +G +G P      GPPGP G  GP
Sbjct: 1293 RLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGP 1341



 Score =  748 bits (1931), Expect = 0.0
 Identities = 484/1192 (40%), Positives = 581/1192 (48%), Gaps = 205/1192 (17%)

Query: 485  EYLRGPKGDTGPPGPPGPAGIPGP-----SGKRGPRGIPGPHGNPGLPGLPGPKGPKGDP 539
            E + G KG+ G  G  GP G PG      +G      + G  G+ G  G PGP GP G P
Sbjct: 220  ERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLP 279

Query: 540  GFSPG--QPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPG 597
            G S G  +  PG+ G QG  G  G PG  G +G+KG+ G PGL GE GI G  G+IG PG
Sbjct: 280  GESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPG 339

Query: 598  Y------------PGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPE--GERGIPGIRGK 643
            +             G +G  GP G  G +G QG  G PG  G  G    G RG PG  G 
Sbjct: 340  FRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGL 399

Query: 644  KGFKGRQGFPGD--FGDRGPAGLDGSPGLVGGTGPP----------------GFPGLRGS 685
            KG KG +G PG    G  G  G  GSPGL G  GPP                G PG  GS
Sbjct: 400  KGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGS 459

Query: 686  VGPVGPIGPAG-----------IPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDK 734
             G  G  GP G           IPGP GL G  GL G+KG  G QG AG  G PG PG+ 
Sbjct: 460  PGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNT 519

Query: 735  GAVGLPGPPGMRGKSG----------PSGQT---GDPGLQGPSGPPGPEGFPGDIGIPGQ 781
            G  G PG PG +G  G          P GQ    GDPGL+G  G  G +G PG  G+ G 
Sbjct: 520  GLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGL 579

Query: 782  NGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGE--LGPRGKPGQKGYAGEPGPEGLK 839
             GP+G   L G +G  GPPG  G+ G  GP G  G    GP+G+PG +G  G PG  G  
Sbjct: 580  PGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPP 639

Query: 840  GEVGDQGNI-------GKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGV--M 890
            GE G +G +       G  G  GP G PG  G  G  G  G+ G PG  GP GE G+  +
Sbjct: 640  GEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI 699

Query: 891  GYPGPP------GVPGPIGPLGLPGHVG--------------------ARGPPGSQGPKG 924
            G+PGPP      G PG  G LG PG +G                      G PG+ G  G
Sbjct: 700  GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 925  QRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGE-----------RGFQGK 973
            +RG+ G  G +G  G+ G  G  G++G  GP G  G+ G PGE           RG QG 
Sbjct: 760  ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819

Query: 974  PGLQGLPGSTGDR-----------------GLPGE---PGLRGLQGDVGP------PGEM 1007
            PGL GL G  G R                 G PGE   PG+ G QG++GP      PG  
Sbjct: 820  PGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNP 879

Query: 1008 GMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVP 1067
            G+ GPPG +G  G+ G PGA   +G  G  G  G PG RG PG PG +G +G  G KG  
Sbjct: 880  GILGPPGEDGVIGMMGFPGA---IGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQ 936

Query: 1068 GGRGLPGED------GEKGEMGLPGIIGPLGRSGQ---TGLPGPEGIVGIPGQRGRPGKK 1118
            G +G PG        G+KGE GL G  G  G  G     G+PG +G+ G+PG  G PG +
Sbjct: 937  GDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPR 996

Query: 1119 GDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQP 1178
            GD G  G  GE G RG PG +G  G  G++G RG +G  G  G  G PGI G +G +G+P
Sbjct: 997  GDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056

Query: 1179 GPS-----GLPGPKGEKGYPGEDSTV-----------LGPPGPRGEPGPVGDQGERGEPG 1222
            G S     G PGP G+ G PG+               LGP GP G PG  G  G  G+PG
Sbjct: 1057 GYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPG 1116

Query: 1223 AEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPG 1282
              G  G  G+ GL G  G +GPPG PG  G  G  G R   G++G+ G PGP+G+ G  G
Sbjct: 1117 PHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIR---GDQGRDGIPGPAGEKGETG 1173

Query: 1283 -LQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSS 1341
             L+   GP+G  G  GA G  G PG  G PG++G  G  G  G TG+ G PGPPG+ G+ 
Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233

Query: 1342 GLPGSPGIQGPKGEQGLPGQPG--------IQGKRGHRGAQGDQGPCGDPGLKGQ----- 1388
             +PG  G +GP G +G PG PG        + G +G +G+ G  GP G PG  G      
Sbjct: 1234 -IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPG 1292

Query: 1389 -------PGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGII- 1440
                   PG  G +G  GFQGFPG KG +G+ G +G  GP GPIG +G  G  G  G + 
Sbjct: 1293 RLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLK 1352

Query: 1441 -----GPTGRTGPRGEKGFRGETGPQ---------GPRGQPGPPGPPGAPGP 1478
                 G  G  G  GE G +GE GP          GPRG+PG  G PG PGP
Sbjct: 1353 IISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGP 1404



 Score =  719 bits (1856), Expect = 0.0
 Identities = 466/1076 (43%), Positives = 533/1076 (49%), Gaps = 162/1076 (15%)

Query: 491  KGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGN--------PGLPGLPGPKGPKGDPGF- 541
            KGD G PGPPGP G  GP G  GP G+PG  G+        PG PGL G KG +G PG  
Sbjct: 353  KGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKD 412

Query: 542  ------------------SPGQPVP--------GEKGDQGLSGLMGPPGMQGDKGLKGHP 575
                              SPG P P        G  GD GL G +G PG+ G  G KG P
Sbjct: 413  AMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEP 472

Query: 576  GL-----PGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLG 630
            GL     P +PG  G+PG  G  G  G PGRQG AG +G+PG  G  G  G PG  G  G
Sbjct: 473  GLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQG 532

Query: 631  -------------PEGERGIPG---IRGKKGFKGRQGFPGDFGDRGPAGLDGS---PGLV 671
                         PEG+ G+PG   +RG+ G KG  G PG  G +G  G  G     G  
Sbjct: 533  DPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEK 592

Query: 672  GGTGPPGFPGLRGSVGPVGPIGPAGI--PGPMGLSGNKGLPGIKGDKGEQGTAGELGE-- 727
            G  GPPG PG  GS GP GP GP G    G  GL G +G+PG  G  GE G  GEL    
Sbjct: 593  GDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652

Query: 728  --PGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPG--------PEGFPGDIG 777
              PG PG  G  G PGP G  G  G  G+ GDPGL GP G PG        P G  GD G
Sbjct: 653  PVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQG 712

Query: 778  IPGQNGPEGPKGLLGNRGPPGPPGLKGTQGE-----------------EGPIGAFGELG- 819
             PG  G  G  G +G  G PG PGL G +GE                  G  G  GE+G 
Sbjct: 713  FPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGL 772

Query: 820  -----------------PRGKPGQKGYAGEPGP-----------EGLKGEVGDQGNIGKI 851
                             PRG PGQ G  GE GP           +GL G  G +G  G+ 
Sbjct: 773  PGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRR 832

Query: 852  GETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMG---YPGPPGVPGP------I 902
            G+TGP G PG  G+  S G  GE GSPG  G QGE G +G   YPG PG+ GP      I
Sbjct: 833  GKTGPKGDPGIPGLDRS-GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVI 891

Query: 903  GPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGL---I 959
            G +G PG +G  GPPG+ G  GQRGS G  G+ G++G  GAKGE+GD+G  GP  +   I
Sbjct: 892  GMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVI 951

Query: 960  GKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGES 1019
            G  G PG +GF G PG +   G+ G  G+PG  GL+GL G  GPPG  G  G  G  GE 
Sbjct: 952  GDKGEPGLKGFAGNPGEK---GNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEP 1008

Query: 1020 GLQGEPGAKGDVGTAGSVG--GT-GEPGLRGEPGAPGEEGLQG-----------KDGLKG 1065
            GL+G PG+ G++G  GS G  GT G PG  G PG PG  GLQG           + G  G
Sbjct: 1009 GLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG 1068

Query: 1066 VPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIG 1125
              G  GLPG+ G+KGEMG PG  G LG +G  G PG  G  G+PG+ G  G  G KG  G
Sbjct: 1069 PTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKG 1128

Query: 1126 PTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPG 1185
              G  G RGPPG  G  G  G  G RG  G  G+ GP GE G  G    +  PGP G PG
Sbjct: 1129 LLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLL--RAPPGPRGNPG 1186

Query: 1186 PKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPG--LRGATGQQG 1243
             +G KG    D    G PG  G  G +GD G RG  G EG+ G  G+PG  + G TG +G
Sbjct: 1187 AQGAKG----DRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRG 1242

Query: 1244 PPGEPGDQGEQGLKGERGSE--GNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGI 1301
            PPG  G  G  G  G  GS   G KG KG+ G  G  G PG  G +GP    G  GA G 
Sbjct: 1243 PPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP---PGRLGAPGT 1299

Query: 1302 SGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQ 1361
             G PG  G PG QG PG++G  G  G  G+ GPPG  G  G PG  G  G      LPG 
Sbjct: 1300 PGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGS 1359

Query: 1362 PGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVG 1417
            PG  G  G  G QG+ GP G PG  G  G  G  G  G  G PGP G +G+ G  G
Sbjct: 1360 PGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKG 1415



 Score =  684 bits (1764), Expect = 0.0
 Identities = 438/1047 (41%), Positives = 525/1047 (50%), Gaps = 163/1047 (15%)

Query: 568  DKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAG 627
            DKG     G  G  GE+G PG       PG PG++G  GPEG PGP+G +GF G PG  G
Sbjct: 35   DKGQCFCDGAKGEKGEKGFPG------PPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTG 88

Query: 628  QLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVG 687
                   +G+ GI G  GF G  G PG  G+ GP GL G PG  G  G  GFPGL G+  
Sbjct: 89   S------KGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGT-- 140

Query: 688  PVGPIGPAGIPGPMGLSGNKGLPG--------IKGDKGEQGTAGELGEPGYPGDKGAVGL 739
                +G  GIPG  GL G KG P          KGD G  G  G  G PG PG  G VG 
Sbjct: 141  ----LGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP 196

Query: 740  PGPPGM------RGKSGPSGQTGDP--------GLQGPSGPPGPEG-----FPGDIGIPG 780
            PGPPG        G  GP G  G+         G++G +GPPGP G       G      
Sbjct: 197  PGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTD 256

Query: 781  QNGPEGPKGLLGNRGPPGPPGLKG-TQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLK 839
              G +G KG +G  GPPGP GL G + G E   GA G+ G +GKPG+ G  G PG EG+K
Sbjct: 257  LKGEKGDKGAMGEPGPPGPSGLPGESYGSEK--GAPGDPGLQGKPGKDGVPGFPGSEGVK 314

Query: 840  GE------VGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYP 893
            G       +G+ G  G+ G+ GP G  G      +  EKG+ G+PGP GP+G +G  G  
Sbjct: 315  GNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPS 374

Query: 894  GPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPD--------GLLGEQGIQGAKG 945
            GPPGVPG  G    PG  GA G PG +G KG+RG  G D        G  G  G+ G+ G
Sbjct: 375  GPPGVPGSPGS-SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPG 433

Query: 946  EKGDQG----KRGP---HGLIGKTGNPGERGFQGK-----------------PGLQGLPG 981
              G  G    ++GP   HGL G  G+PG  G  G                  PGL GLPG
Sbjct: 434  PPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493

Query: 982  STGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTA----GSV 1037
              G +G+PG  G  GL+G  G PG  G+   PG  G  G QG+PG KG+ G      G V
Sbjct: 494  LHGVKGIPGRQGAAGLKGSPGSPGNTGL---PGFPGFPGAQGDPGLKGEKGETLQPEGQV 550

Query: 1038 GGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRG---LPGEDGEKGEMGLPGIIGPLGRS 1094
            G  G+PGLRG+PG  G +G+ G  G+KG+PG +G   L GE G++G  G PG  G  G +
Sbjct: 551  GVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPA 610

Query: 1095 GQTGLPG--PEGIVGIPGQRGRPGKKGDKGQIGPTGEV----------GSRGPPGKIGKS 1142
            G  G PG  P+G  G+ G +G PG  G  G+ GP GE+          G  GPPG  G  
Sbjct: 611  GPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQ 670

Query: 1143 GPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSG------------LPGPKGEK 1190
            GP G  G+ G  G  GL GPDGEPGIPG  G  G PGP G             PG  GE 
Sbjct: 671  GPPGIPGSLGKCGDPGLPGPDGEPGIPGI-GFPGPPGPKGDQGFPGTKGSLGCPGKMGEP 729

Query: 1191 GYPGEDS----------TVLGPPGPRGEPGPVGDQGERGE------PGAEGYKGHVGVPG 1234
            G PG+             + G PG  G PG  G+ GE GE      PG  G  G+ G+ G
Sbjct: 730  GLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDG 789

Query: 1235 LRGATGQQGPPGEPGD--------QGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQ-- 1284
             RG  GQ GPPGE G         +G QGL G  G +G +G++G  GP G PGIPGL   
Sbjct: 790  PRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRS 849

Query: 1285 ---------GLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPP 1335
                     G+ G +G  G  G  G  GNPG +GPPG+ G+ G+ G P   G  G PGPP
Sbjct: 850  GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFP---GAIGPPGPP 906

Query: 1336 GVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQ---GPCGDPGLKGQPGEY 1392
            G  G+ G  GSPGI G KG++G PG  G QG +G+ G        G  G+PGLKG  G  
Sbjct: 907  GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP 966

Query: 1393 GVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEK 1452
            G +G  G  G PG KG +G  G  G  GP+G +G  GN G  G  GI G  G  G  G K
Sbjct: 967  GEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026

Query: 1453 GFRGETGPQGPRGQPGPPGPPGAPGPR 1479
            G RG  G  G  G+PG PG  G  G +
Sbjct: 1027 GKRGTLGFPGRAGRPGLPGIHGLQGDK 1053



 Score =  649 bits (1674), Expect = 0.0
 Identities = 398/908 (43%), Positives = 471/908 (51%), Gaps = 76/908 (8%)

Query: 482  LEMEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGF 541
            L+ E   G  GD G  G PG  G+ G  G  G +G+PGP G   L G  G +GP GDPG 
Sbjct: 544  LQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPG- 602

Query: 542  SPGQP---------------VPGEKGDQGLSGLMGPPGMQGDKG-LKGHPGLPGLPGEQG 585
            SPG P                PG +G QG+ G  GPPG  G +G L     +PG PG  G
Sbjct: 603  SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPG 662

Query: 586  IPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKG 645
             PG  G  G PG PG  G  G  G PGP G  G  G  G  G  GP+G++G PG +G  G
Sbjct: 663  PPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI-GFPGPPGPKGDQGFPGTKGSLG 721

Query: 646  FKGRQGFPGDFGDRGPAGLDGSPGLV--GGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGL 703
              G+ G PG  G  G  G  G P +   GG G PGFPG RG+ G  G IG  G+PG  G 
Sbjct: 722  CPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGT 781

Query: 704  SGNKGLPGIKGDKGEQGTAGELGEPG--YPGDKGAVGLPGPPGMRGKSGPSGQT---GDP 758
             GN+GL G +GD G+ G  GE G PG    G +GA GLPG  G++G+ G  G+T   GDP
Sbjct: 782  PGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDP 841

Query: 759  GLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAF--- 815
            G+ G        GFPG+ G PG  G +G  G LG RG PG PG+ G  GE+G IG     
Sbjct: 842  GIPGLD----RSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFP 897

Query: 816  GELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGER 875
            G +GP G PG  G  G+ G  G+ G  G +G  G  GE G  G PG   ++  IG+KGE 
Sbjct: 898  GAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP 957

Query: 876  GSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLL 935
            G  G  G  GEKG  G PG PG+ G  G  G  G  G RG  GS G  G+ G RG  G +
Sbjct: 958  GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSM 1017

Query: 936  GEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQ-----GLPGSTGDRGLPG 990
            G  G+ G+KG++G  G  G  G  G  G  G +G +G+PG       G PG TGD GLPG
Sbjct: 1018 GNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPG 1077

Query: 991  EPGLRGLQGDVGPPGEMGMEGP---PGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRG 1047
            + G +G  G  GPPG +G  GP   PG+ G  GL G+PG  GD+G  G  G  G PG+RG
Sbjct: 1078 DMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRG 1137

Query: 1048 EPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMG-LPGIIGPLGRSGQTGLPGPEGIV 1106
             PG PG  G  G  G++G  G  G+PG  GEKGE G L    GP G  G  G  G  G  
Sbjct: 1138 PPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAP 1197

Query: 1107 GIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGK--SGPKGARGTRGAVGHLGLMGPDG 1164
            G PG  GR G  GD G  GPTG  G  GPPG  G    G  G RG  G+ G  G  GP G
Sbjct: 1198 GFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPG 1257

Query: 1165 EP-----GIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERG 1219
             P     GI G +G  G PGP G PG  G+ G PG     LG PG  G PGP GD G +G
Sbjct: 1258 PPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR----LGAPGTPGLPGPRGDPGFQG 1313

Query: 1220 EPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPG 1279
             PG +G KG+   PG  G+    GPPG  G +G  G++G+ G+       G+PGP G PG
Sbjct: 1314 FPGVKGEKGN---PGFLGSI---GPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPG 1367

Query: 1280 IPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKG 1339
             PG+QG  GP G                  PPG  G  G RG PG+ G  G PGP G KG
Sbjct: 1368 EPGMQGEPGPPG------------------PPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409

Query: 1340 SSGLPGSP 1347
            + G  G P
Sbjct: 1410 NKGSKGEP 1417



 Score =  394 bits (1012), Expect = e-109
 Identities = 257/653 (39%), Positives = 318/653 (48%), Gaps = 97/653 (14%)

Query: 913  ARGPPGSQG----PKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGER 968
            A  P  S+G     KGQ    G  G  GE+G  G  G  G +G  GP GL      PG +
Sbjct: 22   AAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGL------PGPQ 75

Query: 969  GFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAK 1028
            G +G PGL GL GS G RG+ G PG  G  G  G PG  G  G  G  G SG +GE G  
Sbjct: 76   GPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFP 135

Query: 1029 GDVGTAGSVGGTGEPGLRGEPGAPGEE-----GLQGKDGLKGVPGGRGLPGEDGEKGEMG 1083
            G  GT G  G  G  GL+G+ GAP +E       +G  GL G PG +GLPG  G  G +G
Sbjct: 136  GLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVG 195

Query: 1084 LPGIIGPLGRSGQTGLPGPEGIVG--IPGQRGRPGKKGDKGQIGPTGEV----------- 1130
             PG  G  G  G  G  GP+G +G  + G +G  G KG  G  GP G V           
Sbjct: 196  PPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRT 255

Query: 1131 ---GSRGPPGKIGKSGPKGARGT--------RGAVGHLGLMGPDGEPGIPGYRGHQGQPG 1179
               G +G  G +G+ GP G  G         +GA G  GL G  G+ G+PG+ G +G  G
Sbjct: 256  DLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG 315

Query: 1180 PSGLPGPKGEKGYPGE-----------------------DSTVLGPPGPRGEPGPVGDQG 1216
              G PG  GE G  G+                       D    GPPGPRG  GP G  G
Sbjct: 316  NRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSG 375

Query: 1217 ERGEPGAEG-----YKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGA 1271
              G PG+ G      +G  G PGL+G+ G++G PG+    G  G  G  GS G  G  G 
Sbjct: 376  PPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDA-MGTPGSPGCAGSPGLPGSPGP 434

Query: 1272 PGPSG----KPGIPGLQGLLGPKGIQGYHGADGISGNPGKI--------GPPGKQGLPG- 1318
            PGP G    + G PG  GL G  G  G  G DG  G PG +        GPPG  GLPG 
Sbjct: 435  PGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGL 494

Query: 1319 --IRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHR-GAQG 1375
              ++G PGR G AG  G PG  G++GLPG PG  G +G+      PG++G++G     +G
Sbjct: 495  HGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGD------PGLKGEKGETLQPEG 548

Query: 1376 DQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLG 1435
              G  GDPGL+GQPG  G+ G+ G  G  G  GP+G+  + G  G +GP G  G+ G  G
Sbjct: 549  QVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPG 608

Query: 1436 REGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQMDINAAI 1488
              G  GP G  GP+GE G       QG +G PG PGPPG  GPR ++ ++  +
Sbjct: 609  PAGPAGPPGY-GPQGEPGL------QGTQGVPGAPGPPGEAGPRGELSVSTPV 654



 Score =  221 bits (562), Expect = 6e-57
 Identities = 132/310 (42%), Positives = 157/310 (50%), Gaps = 19/310 (6%)

Query: 475  YEDLNTMLEMEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPG-LPGPK 533
            ++ +  +L    +RGP G  G PG PGP GI G  G+    GIPGP G  G  G L  P 
Sbjct: 1123 FKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGR---DGIPGPAGEKGETGLLRAPP 1179

Query: 534  GPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPG--FAG 591
            GP+G+PG    Q   G++G  G  GL G  G  GD G +G  G+ G PG  G+PG    G
Sbjct: 1180 GPRGNPG---AQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPG 1236

Query: 592  NIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQG 651
              G+ G PG +G  G  G PGP G+   IG  G+ G +G  G +G PG  G  G  GR G
Sbjct: 1237 QTGNRGPPGSRGSPGAPGPPGPPGSH-VIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLG 1295

Query: 652  FPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPG 711
             PG  G  GP G  G  G  G  G  G PG  GS+GP GPIGP G PG  G  G   +  
Sbjct: 1296 APGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIIS 1355

Query: 712  IKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEG 771
            + G  G  GT    GEPG  G+      PGPPG  G  GP G  G PG  G  G PGP G
Sbjct: 1356 LPGSPGPPGTP---GEPGMQGE------PGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAG 1406

Query: 772  FPGDIGIPGQ 781
              G+ G  G+
Sbjct: 1407 EKGNKGSKGE 1416


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
            sapiens]
          Length = 1494

 Score =  767 bits (1981), Expect = 0.0
 Identities = 499/1206 (41%), Positives = 582/1206 (48%), Gaps = 239/1206 (19%)

Query: 491  KGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGE 550
            KGD G PG PGP G+PGP G  GP G PGP G  G PG  GP+GPKG  G    + V G 
Sbjct: 170  KGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMG----ERVIGH 225

Query: 551  KGDQGLSGLMGPPG-----------------MQGDKGLKGHPGLPGLPGEQGIPG--FAG 591
            KG++G+ GL GPPG                 ++G+KG KG  G PG PG  G+PG  +  
Sbjct: 226  KGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGS 285

Query: 592  NIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQG 651
              G+PG PG QG  G +G PG  G++G             +G RG PG+ G+ G KG++G
Sbjct: 286  EKGAPGDPGLQGKPGKDGVPGFPGSEGV------------KGNRGFPGLMGEDGIKGQKG 333

Query: 652  FPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMG-----LSGN 706
              G  G RGP     +    G  G PG PG RG+ GP GP GP G+PG  G     L G 
Sbjct: 334  DIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGA 393

Query: 707  KGLPGIKGDKGEQGTAGE--LGEPGYPGDKGAVGLPG----------------PPGMRGK 748
             G PG+KG KGE+G  G+  +G PG PG  G+ GLPG                PPG  G 
Sbjct: 394  PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGL 453

Query: 749  SGPSGQTGDPGLQGPSG--------------PPGPEGFPGDIGIPGQNGPEGPKGLLGNR 794
             G  G  G PG+ GP G              PPG  G PG  G+ G  G +G  GL G+ 
Sbjct: 454  PGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSP 513

Query: 795  GPPG---------------PPGLKGTQGE----EGPIGAFGELGPRGKPGQKGYAGEPGP 835
            G PG                PGLKG +GE    EG +G  G+ G RG+PG+KG  G PG 
Sbjct: 514  GSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGT 573

Query: 836  EGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGE------KGV 889
             G+KG  G +G +   GE G  G PG+ G  GS G  G  G PG  GPQGE      +GV
Sbjct: 574  PGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGTQGV 632

Query: 890  MGYPGPPG-------------VPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRG------ 930
             G PGPPG             VPGP GP G PGH G +GPPG  G  G+ G  G      
Sbjct: 633  PGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDG 692

Query: 931  -----------PDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPG------------- 966
                       P G  G+QG  G KG  G  GK G  GL GK G PG             
Sbjct: 693  EPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP 752

Query: 967  -------ERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGT--EG 1017
                   ERG  G+ G  GLPG  G  G PG  GL G +GD G PG  G +GPPG   EG
Sbjct: 753  GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812

Query: 1018 ESGLQGEPGA---KGDVGTAGSVGGTGEPGL-----------RGEPGAPGEEGLQGKDGL 1063
              G QG PG    KG  G  G  G  G+PG+            G PG PG +G  G  G 
Sbjct: 813  PRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ 872

Query: 1064 KGVPGGRGL---PGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPG---QRGRPGK 1117
            +G PG  G+   PGEDG  G MG PG IGP G  G  G PG  G  GIPG   QRG PG 
Sbjct: 873  RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932

Query: 1118 KG---DKGQIGPT---------------------GEVGSRGPPGKIGKSGPKGARGTRGA 1153
            KG   DKG  GP+                     GE G+RG PG  G  G KG  G  G 
Sbjct: 933  KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992

Query: 1154 VGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKG---YPGE--------------- 1195
             G  G +G  G PG PG RG  G  G  G+PG KG++G   +PG                
Sbjct: 993  PGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGD 1052

Query: 1196 -------DSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEP 1248
                   + T  GPPGP G+PG  GD G++GE G  G  GH+G  G  GA G  G PG P
Sbjct: 1053 KGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLP 1112

Query: 1249 GDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKI 1308
            G  G  G   + G +G KG  G PG  G PG+PG  G  GP GI+G  G DGI G  G+ 
Sbjct: 1113 GKPGPHG---DLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEK 1169

Query: 1309 G-------PPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQ 1361
            G       PPG +G PG +G  G  G   APG PG+ G  G  G  G +GP G +G PG 
Sbjct: 1170 GETGLLRAPPGPRGNPGAQGAKGDRG---APGFPGLPGRKGAMGDAGPRGPTGIEGFPGP 1226

Query: 1362 PG-----IQGKRGHRGAQGDQGPCGDPGLKGQPGEY--GVQGLTGFQGFPGPKGPEGDAG 1414
            PG     I G+ G+RG  G +G  G PG  G PG +  G++G  G  G PGPKGP G AG
Sbjct: 1227 PGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286

Query: 1415 IVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPG 1474
             +G  G  G  G  G  GP G  G  G  G  G +G  GF G  GP GP G  GPPG  G
Sbjct: 1287 DMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRG 1346

Query: 1475 APGPRK 1480
             PG  K
Sbjct: 1347 DPGTLK 1352



 Score =  754 bits (1947), Expect = 0.0
 Identities = 490/1176 (41%), Positives = 578/1176 (49%), Gaps = 189/1176 (16%)

Query: 488  RGPKGDTGPPGPPGPAGIPGPS--------------GKRGPRGIPG------PHGNPGLP 527
            +G KG  G PGPPGP+G+PG S              GK G  G+PG        GN G P
Sbjct: 261  KGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFP 320

Query: 528  GLPGP---KGPKGD---PGF-----------------SPGQPVP-GEKGDQGLSGLMGPP 563
            GL G    KG KGD   PGF                 +PG P P G +G QG SG  G P
Sbjct: 321  GLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVP 380

Query: 564  GMQGDK--GLKGHPGLPGLPGEQG-----------IPGFAGNIGSPGYPGRQGLAGPEGN 610
            G  G    GL+G PG PGL G +G            PG  G  GSPG PG  G  GP G+
Sbjct: 381  GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGD 440

Query: 611  -------PGPKGAQGFIGSPGEAGQLGPEGERG--------IPGIRGKKGFKGRQGFPGD 655
                   PG  G  G++GSPG  G  GP+GE G        IPG  G  G  G  G  G 
Sbjct: 441  IVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGI 500

Query: 656  FGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVG-------------PVGPIGPAGIPGPMG 702
             G +G AGL GSPG  G TG PGFPG  G+ G             P G +G  G PG  G
Sbjct: 501  PGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRG 560

Query: 703  LSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQG 762
              G KGL GI G  G +G  G  GE    G+KG  G PG PG  G  GP+G  G PG  G
Sbjct: 561  QPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY-G 619

Query: 763  PSGPPGPEGFPGDIGIPGQNGPEGPKGLL-------GNRGPPGPPGLKGTQGEEGPIGAF 815
            P G PG +G  G  G PG  G  GP+G L       G  GPPGPPG  G QG  G  G+ 
Sbjct: 620  PQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSL 679

Query: 816  GELGPRGKPGQKG--------YAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTG 867
            G+ G  G PG  G        + G PGP+G +G  G +G++G  G+ G  GLPG+ G+ G
Sbjct: 680  GKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPG 739

Query: 868  SIGEK--------GERGSPGPLGPQGEKGVMGYPGPPGVPG---------PIGPLGLPGH 910
            + GE         G  G PG  G  GE G +G PG PG+PG         P G  G PG 
Sbjct: 740  AKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGP 799

Query: 911  VGARGPPGS--QGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRG--PHGLIGKTGNPG 966
             G +GPPG   +GP+G +G  G +GL G+QG +G  G KGD G  G    G  G+TG+PG
Sbjct: 800  PGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPG 859

Query: 967  ------------ERGFQGKPGL------------QGLPGSTGDRGLPGEPGLRGLQGDVG 1002
                        +RG+ G PG+             G PG+ G  G PG PG  G +G  G
Sbjct: 860  IPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPG 919

Query: 1003 PPGEMGMEGPPGTEGESGLQGEPGA---------KGDVGTAGSVGGTGEPGLRGEPGAPG 1053
             PG  G  G PG +GE G +G PG          KG+ G  G  G  GE G RG PG PG
Sbjct: 920  IPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPG 979

Query: 1054 EEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRG 1113
             +GL+G  G  G PG RG  G  G  GE GL GI G +G  G  G  G  G +G PG+ G
Sbjct: 980  LKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAG 1039

Query: 1114 RPGK------KGDKGQIGPT-----GEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGP 1162
            RPG       +GDKG+ G +     G  G  G PG  G  G KG  G  G  GHLG  GP
Sbjct: 1040 RPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGP 1099

Query: 1163 DGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRG---EPGPVG---DQG 1216
            +G PG PG  G  G+PGP G  G KG KG  G    + GPPG  G    PGP+G   DQG
Sbjct: 1100 EGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPG-IRGPPGLPGFPGSPGPMGIRGDQG 1158

Query: 1217 ERGEPGAEGYKGHVGV----PGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAP 1272
              G PG  G KG  G+    PG RG  G QG  G+ G  G  GL G +G+ G+ G +G  
Sbjct: 1159 RDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPT 1218

Query: 1273 GPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQG--LPGIRGGPGRTGLAG 1330
            G  G PG PGL G + P G  G  G  G  G+PG  GPPG  G  + GI+G  G  G  G
Sbjct: 1219 GIEGFPGPPGLPGAIIP-GQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPG 1277

Query: 1331 APGPPGVKGSSG------LPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPG 1384
              GPPG  G  G       PG+PG+ GP+G+ G  G PG++G++G+ G  G  GP G  G
Sbjct: 1278 PKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIG 1337

Query: 1385 LKGQPGEYGVQG---LTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIG 1441
             KG PG  G  G   +    G PGP G  G+ G+ G  GP GP G+ G  GP G+ G  G
Sbjct: 1338 PKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDG 1397

Query: 1442 PTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPG 1477
              G  GP GEKG +G  G  GP G  G PG  G  G
Sbjct: 1398 KPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433



 Score =  754 bits (1946), Expect = 0.0
 Identities = 509/1309 (38%), Positives = 597/1309 (45%), Gaps = 329/1309 (25%)

Query: 489  GPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGD------PGFS 542
            G KG+ G  G PGP G PG  G  GP G+PGP G  G PGLPG  G KG       PGFS
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 543  PGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFA------------ 590
                +PG  G+ G  GL+G PG  G KG +G PGLPG  G  GIPG A            
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 591  --------GNIGSPGYPGRQGLAGPEGNP---GPKGAQGFIGSPGEAGQLGP-------- 631
                    G+ G PG PG QGL GP G P   GP G  GF G PG  G  GP        
Sbjct: 163  EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERV 222

Query: 632  ---EGERGIPGIRGKKG-----------------FKGRQGFPGDFGDRGPAGLDGSPGLV 671
               +GERG+ G+ G  G                  KG +G  G  G+ GP G  G PG  
Sbjct: 223  IGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGES 282

Query: 672  GGT--GPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPG 729
             G+  G PG PGL+G     G  G  G PG  G+ GN+G PG+ G+ G +G  G++G PG
Sbjct: 283  YGSEKGAPGDPGLQGK---PGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPG 339

Query: 730  YPG---------DKGAVGLPGPPGMRGKSGPSGQTGDPGLQGP----------------- 763
            + G         +KG  G PGPPG RG  GP G +G PG+ G                  
Sbjct: 340  FRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGL 399

Query: 764  -----------------------------SGPPGPEGFPGDI------------------ 776
                                          G PGP G PGDI                  
Sbjct: 400  KGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGS 459

Query: 777  -GIPGQNGPEGPKGLLGNR-----GPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYA 830
             GIPG +GP+G  GLL  +     GPPG PGL G  G +G  G  G  G +G PG  G  
Sbjct: 460  PGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNT 519

Query: 831  GEPGPEGLKGEVGDQGNIGKIGET----GPVGLPGEVGMTGSIGEK-------------- 872
            G PG  G  G  GD G  G+ GET    G VG+PG+ G+ G  G K              
Sbjct: 520  GLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGL 579

Query: 873  ----------------------GERGSPGPLGP--------------QGEKGVMGYPGPP 896
                                  G  GSPGP GP              QG +GV G PGPP
Sbjct: 580  PGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPP 639

Query: 897  G-------------VPGPIGPLGLPGHVGARGP---PGSQGPKGQRGSRGPDGLLGEQGI 940
            G             VPGP GP G PGH G +GP   PGS G  G  G  GPDG  G  GI
Sbjct: 640  GEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI 699

Query: 941  --QGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQG--------LPGSTGDRGLPG 990
               G  G KGDQG  G  G +G  G  GE G  GKPGL G        +PG  G  G PG
Sbjct: 700  GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 991  EPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSV--------GGTGE 1042
            E G  G  G++G PG  G+ G PG EG  G +G+PG  G  G  G          G  G 
Sbjct: 760  ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819

Query: 1043 PGL---------------RGEPGAPG--EEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLP 1085
            PGL               +G+PG PG    G  G+ G  G+PG +G  G  G++G  G P
Sbjct: 820  PGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNP 879

Query: 1086 GIIGPLGRSGQTGL---------PGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPP 1136
            GI+GP G  G  G+         PGP G  G PGQRG PG  G KGQ G  G  G +G  
Sbjct: 880  GILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDK 939

Query: 1137 GKIGKS------GPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEK 1190
            G  G S      G KG  G +G  G+ G  G  G PG+PG +G +G PGP+G PGP+G+ 
Sbjct: 940  GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999

Query: 1191 GYPGEDSTVLGPPGPRGEPGPVGDQ---GERGEPGAEGYKGHVGVPGLRGATGQQGP--- 1244
            G  G      G PG RG PG +G+    G +G+ G  G+ G  G PGL G  G QG    
Sbjct: 1000 GSTGNP----GEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE 1055

Query: 1245 --------PGEPGDQGEQGLKGERGSEGNKGKKGAP---------GPSGKPGIPGLQGLL 1287
                    PG PG  G+ GL G+ G +G  G+ G P         G  G PG PGL G  
Sbjct: 1056 PGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKP 1115

Query: 1288 GPKGIQGYHGADGISGNPGKIGPPGKQGLP------GIRGGPGRTGLAGAPGPPGVKGSS 1341
            GP G  G+ G  G+ G PG  GPPG  G P      GIRG  GR G+   PGP G KG +
Sbjct: 1116 GPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGI---PGPAGEKGET 1172

Query: 1342 GL-------PGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPC------GDPGL--- 1385
            GL        G+PG QG KG++G PG PG+ G++G  G  G +GP       G PGL   
Sbjct: 1173 GLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGA 1232

Query: 1386 --KGQPGEYGVQGLTGFQGFPGPKGP--------EGDAGIVGISGPKGPIGHRGNTGPLG 1435
               GQ G  G  G  G  G PGP GP        +GD G +G  GPKGP G  G+ GP G
Sbjct: 1233 IIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPG 1292

Query: 1436 REGIIGPTGRTGPRGEKGFRGETGPQGPRGQP------GPPGPPGAPGP 1478
            R G  G  G  GPRG+ GF+G  G +G +G P      GPPGP G  GP
Sbjct: 1293 RLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGP 1341



 Score =  748 bits (1931), Expect = 0.0
 Identities = 484/1192 (40%), Positives = 581/1192 (48%), Gaps = 205/1192 (17%)

Query: 485  EYLRGPKGDTGPPGPPGPAGIPGP-----SGKRGPRGIPGPHGNPGLPGLPGPKGPKGDP 539
            E + G KG+ G  G  GP G PG      +G      + G  G+ G  G PGP GP G P
Sbjct: 220  ERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLP 279

Query: 540  GFSPG--QPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPG 597
            G S G  +  PG+ G QG  G  G PG  G +G+KG+ G PGL GE GI G  G+IG PG
Sbjct: 280  GESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPG 339

Query: 598  Y------------PGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPE--GERGIPGIRGK 643
            +             G +G  GP G  G +G QG  G PG  G  G    G RG PG  G 
Sbjct: 340  FRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGL 399

Query: 644  KGFKGRQGFPGD--FGDRGPAGLDGSPGLVGGTGPP----------------GFPGLRGS 685
            KG KG +G PG    G  G  G  GSPGL G  GPP                G PG  GS
Sbjct: 400  KGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGS 459

Query: 686  VGPVGPIGPAG-----------IPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDK 734
             G  G  GP G           IPGP GL G  GL G+KG  G QG AG  G PG PG+ 
Sbjct: 460  PGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNT 519

Query: 735  GAVGLPGPPGMRGKSG----------PSGQT---GDPGLQGPSGPPGPEGFPGDIGIPGQ 781
            G  G PG PG +G  G          P GQ    GDPGL+G  G  G +G PG  G+ G 
Sbjct: 520  GLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGL 579

Query: 782  NGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGE--LGPRGKPGQKGYAGEPGPEGLK 839
             GP+G   L G +G  GPPG  G+ G  GP G  G    GP+G+PG +G  G PG  G  
Sbjct: 580  PGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPP 639

Query: 840  GEVGDQGNI-------GKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGV--M 890
            GE G +G +       G  G  GP G PG  G  G  G  G+ G PG  GP GE G+  +
Sbjct: 640  GEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI 699

Query: 891  GYPGPP------GVPGPIGPLGLPGHVG--------------------ARGPPGSQGPKG 924
            G+PGPP      G PG  G LG PG +G                      G PG+ G  G
Sbjct: 700  GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 925  QRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGE-----------RGFQGK 973
            +RG+ G  G +G  G+ G  G  G++G  GP G  G+ G PGE           RG QG 
Sbjct: 760  ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819

Query: 974  PGLQGLPGSTGDR-----------------GLPGE---PGLRGLQGDVGP------PGEM 1007
            PGL GL G  G R                 G PGE   PG+ G QG++GP      PG  
Sbjct: 820  PGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNP 879

Query: 1008 GMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVP 1067
            G+ GPPG +G  G+ G PGA   +G  G  G  G PG RG PG PG +G +G  G KG  
Sbjct: 880  GILGPPGEDGVIGMMGFPGA---IGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQ 936

Query: 1068 GGRGLPGED------GEKGEMGLPGIIGPLGRSGQ---TGLPGPEGIVGIPGQRGRPGKK 1118
            G +G PG        G+KGE GL G  G  G  G     G+PG +G+ G+PG  G PG +
Sbjct: 937  GDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPR 996

Query: 1119 GDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQP 1178
            GD G  G  GE G RG PG +G  G  G++G RG +G  G  G  G PGI G +G +G+P
Sbjct: 997  GDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056

Query: 1179 GPS-----GLPGPKGEKGYPGEDSTV-----------LGPPGPRGEPGPVGDQGERGEPG 1222
            G S     G PGP G+ G PG+               LGP GP G PG  G  G  G+PG
Sbjct: 1057 GYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPG 1116

Query: 1223 AEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPG 1282
              G  G  G+ GL G  G +GPPG PG  G  G  G R   G++G+ G PGP+G+ G  G
Sbjct: 1117 PHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIR---GDQGRDGIPGPAGEKGETG 1173

Query: 1283 -LQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSS 1341
             L+   GP+G  G  GA G  G PG  G PG++G  G  G  G TG+ G PGPPG+ G+ 
Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233

Query: 1342 GLPGSPGIQGPKGEQGLPGQPG--------IQGKRGHRGAQGDQGPCGDPGLKGQ----- 1388
             +PG  G +GP G +G PG PG        + G +G +G+ G  GP G PG  G      
Sbjct: 1234 -IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPG 1292

Query: 1389 -------PGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGII- 1440
                   PG  G +G  GFQGFPG KG +G+ G +G  GP GPIG +G  G  G  G + 
Sbjct: 1293 RLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLK 1352

Query: 1441 -----GPTGRTGPRGEKGFRGETGPQ---------GPRGQPGPPGPPGAPGP 1478
                 G  G  G  GE G +GE GP          GPRG+PG  G PG PGP
Sbjct: 1353 IISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGP 1404



 Score =  733 bits (1891), Expect = 0.0
 Identities = 475/1108 (42%), Positives = 550/1108 (49%), Gaps = 171/1108 (15%)

Query: 491  KGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGN--------PGLPGLPGPKGPKGDPGF- 541
            KGD G PGPPGP G  GP G  GP G+PG  G+        PG PGL G KG +G PG  
Sbjct: 353  KGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKD 412

Query: 542  ------------------SPGQPVP--------GEKGDQGLSGLMGPPGMQGDKGLKGHP 575
                              SPG P P        G  GD GL G +G PG+ G  G KG P
Sbjct: 413  AMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEP 472

Query: 576  GL-----PGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLG 630
            GL     P +PG  G+PG  G  G  G PGRQG AG +G+PG  G  G  G PG  G  G
Sbjct: 473  GLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQG 532

Query: 631  -------------PEGERGIPG---IRGKKGFKGRQGFPGDFGDRGPAGLDGS---PGLV 671
                         PEG+ G+PG   +RG+ G KG  G PG  G +G  G  G     G  
Sbjct: 533  DPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEK 592

Query: 672  GGTGPPGFPGLRGSVGPVGPIGPAGI--PGPMGLSGNKGLPGIKGDKGEQGTAGELGE-- 727
            G  GPPG PG  GS GP GP GP G    G  GL G +G+PG  G  GE G  GEL    
Sbjct: 593  GDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652

Query: 728  --PGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPG--------PEGFPGDIG 777
              PG PG  G  G PGP G  G  G  G+ GDPGL GP G PG        P G  GD G
Sbjct: 653  PVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQG 712

Query: 778  IPGQNGPEGPKGLLGNRGPPGPPGLKGTQGE-----------------EGPIGAFGELG- 819
             PG  G  G  G +G  G PG PGL G +GE                  G  G  GE+G 
Sbjct: 713  FPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGL 772

Query: 820  -----------------PRGKPGQKGYAGEPGP-----------EGLKGEVGDQGNIGKI 851
                             PRG PGQ G  GE GP           +GL G  G +G  G+ 
Sbjct: 773  PGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRR 832

Query: 852  GETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMG---YPGPPGVPGP------I 902
            G+TGP G PG  G+  S G  GE GSPG  G QGE G +G   YPG PG+ GP      I
Sbjct: 833  GKTGPKGDPGIPGLDRS-GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVI 891

Query: 903  GPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGL---I 959
            G +G PG +G  GPPG+ G  GQRGS G  G+ G++G  GAKGE+GD+G  GP  +   I
Sbjct: 892  GMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVI 951

Query: 960  GKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGES 1019
            G  G PG +GF G PG +   G+ G  G+PG  GL+GL G  GPPG  G  G  G  GE 
Sbjct: 952  GDKGEPGLKGFAGNPGEK---GNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEP 1008

Query: 1020 GLQGEPGAKGDVGTAGSVG--GT-GEPGLRGEPGAPGEEGLQG-----------KDGLKG 1065
            GL+G PG+ G++G  GS G  GT G PG  G PG PG  GLQG           + G  G
Sbjct: 1009 GLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG 1068

Query: 1066 VPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIG 1125
              G  GLPG+ G+KGEMG PG  G LG +G  G PG  G  G+PG+ G  G  G KG  G
Sbjct: 1069 PTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKG 1128

Query: 1126 PTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPG 1185
              G  G RGPPG  G  G  G  G RG  G  G+ GP GE G  G    +  PGP G PG
Sbjct: 1129 LLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLL--RAPPGPRGNPG 1186

Query: 1186 PKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPG--LRGATGQQG 1243
             +G KG    D    G PG  G  G +GD G RG  G EG+ G  G+PG  + G TG +G
Sbjct: 1187 AQGAKG----DRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRG 1242

Query: 1244 PPGEPGDQGEQGLKGERGSE--GNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGI 1301
            PPG  G  G  G  G  GS   G KG KG+ G  G  G PG  G +GP    G  GA G 
Sbjct: 1243 PPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP---PGRLGAPGT 1299

Query: 1302 SGNPGKIGPPGKQGLPGI---RGGPGRTGLAGAPGPPGVKGSSGLPGSPG------IQGP 1352
             G PG  G PG QG PG+   +G PG  G  G PGP G KG  G+ G PG      + G 
Sbjct: 1300 PGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGS 1359

Query: 1353 KGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGD 1412
             G  G PG+PG+QG+ G  G  G+ GPCG  G  G+ G+ G  G  G +G  G KG  G 
Sbjct: 1360 PGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGP 1419

Query: 1413 AGIVGISGPKGPIGHRGNTGPLGREGII 1440
            AG  G+ G KG  G  G+       G +
Sbjct: 1420 AGSDGLPGLKGKRGDSGSPATWTTRGFV 1447



 Score =  684 bits (1764), Expect = 0.0
 Identities = 438/1047 (41%), Positives = 525/1047 (50%), Gaps = 163/1047 (15%)

Query: 568  DKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAG 627
            DKG     G  G  GE+G PG       PG PG++G  GPEG PGP+G +GF G PG  G
Sbjct: 35   DKGQCFCDGAKGEKGEKGFPG------PPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTG 88

Query: 628  QLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVG 687
                   +G+ GI G  GF G  G PG  G+ GP GL G PG  G  G  GFPGL G+  
Sbjct: 89   S------KGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGT-- 140

Query: 688  PVGPIGPAGIPGPMGLSGNKGLPG--------IKGDKGEQGTAGELGEPGYPGDKGAVGL 739
                +G  GIPG  GL G KG P          KGD G  G  G  G PG PG  G VG 
Sbjct: 141  ----LGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP 196

Query: 740  PGPPGM------RGKSGPSGQTGDP--------GLQGPSGPPGPEG-----FPGDIGIPG 780
            PGPPG        G  GP G  G+         G++G +GPPGP G       G      
Sbjct: 197  PGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTD 256

Query: 781  QNGPEGPKGLLGNRGPPGPPGLKG-TQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLK 839
              G +G KG +G  GPPGP GL G + G E   GA G+ G +GKPG+ G  G PG EG+K
Sbjct: 257  LKGEKGDKGAMGEPGPPGPSGLPGESYGSEK--GAPGDPGLQGKPGKDGVPGFPGSEGVK 314

Query: 840  GE------VGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYP 893
            G       +G+ G  G+ G+ GP G  G      +  EKG+ G+PGP GP+G +G  G  
Sbjct: 315  GNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPS 374

Query: 894  GPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPD--------GLLGEQGIQGAKG 945
            GPPGVPG  G    PG  GA G PG +G KG+RG  G D        G  G  G+ G+ G
Sbjct: 375  GPPGVPGSPGS-SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPG 433

Query: 946  EKGDQG----KRGP---HGLIGKTGNPGERGFQGK-----------------PGLQGLPG 981
              G  G    ++GP   HGL G  G+PG  G  G                  PGL GLPG
Sbjct: 434  PPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493

Query: 982  STGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTA----GSV 1037
              G +G+PG  G  GL+G  G PG  G+   PG  G  G QG+PG KG+ G      G V
Sbjct: 494  LHGVKGIPGRQGAAGLKGSPGSPGNTGL---PGFPGFPGAQGDPGLKGEKGETLQPEGQV 550

Query: 1038 GGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRG---LPGEDGEKGEMGLPGIIGPLGRS 1094
            G  G+PGLRG+PG  G +G+ G  G+KG+PG +G   L GE G++G  G PG  G  G +
Sbjct: 551  GVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPA 610

Query: 1095 GQTGLPG--PEGIVGIPGQRGRPGKKGDKGQIGPTGEV----------GSRGPPGKIGKS 1142
            G  G PG  P+G  G+ G +G PG  G  G+ GP GE+          G  GPPG  G  
Sbjct: 611  GPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQ 670

Query: 1143 GPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSG------------LPGPKGEK 1190
            GP G  G+ G  G  GL GPDGEPGIPG  G  G PGP G             PG  GE 
Sbjct: 671  GPPGIPGSLGKCGDPGLPGPDGEPGIPGI-GFPGPPGPKGDQGFPGTKGSLGCPGKMGEP 729

Query: 1191 GYPGEDS----------TVLGPPGPRGEPGPVGDQGERGE------PGAEGYKGHVGVPG 1234
            G PG+             + G PG  G PG  G+ GE GE      PG  G  G+ G+ G
Sbjct: 730  GLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDG 789

Query: 1235 LRGATGQQGPPGEPGD--------QGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQ-- 1284
             RG  GQ GPPGE G         +G QGL G  G +G +G++G  GP G PGIPGL   
Sbjct: 790  PRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRS 849

Query: 1285 ---------GLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPP 1335
                     G+ G +G  G  G  G  GNPG +GPPG+ G+ G+ G P   G  G PGPP
Sbjct: 850  GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFP---GAIGPPGPP 906

Query: 1336 GVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQ---GPCGDPGLKGQPGEY 1392
            G  G+ G  GSPGI G KG++G PG  G QG +G+ G        G  G+PGLKG  G  
Sbjct: 907  GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP 966

Query: 1393 GVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEK 1452
            G +G  G  G PG KG +G  G  G  GP+G +G  GN G  G  GI G  G  G  G K
Sbjct: 967  GEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026

Query: 1453 GFRGETGPQGPRGQPGPPGPPGAPGPR 1479
            G RG  G  G  G+PG PG  G  G +
Sbjct: 1027 GKRGTLGFPGRAGRPGLPGIHGLQGDK 1053



 Score =  672 bits (1733), Expect = 0.0
 Identities = 425/1000 (42%), Positives = 500/1000 (50%), Gaps = 155/1000 (15%)

Query: 486  YLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQ 545
            Y+ GP G  G PG  G  GIPG  G  G +G PG  GN GLPG PG  G +GDPG     
Sbjct: 481  YIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPG----- 535

Query: 546  PVPGEKGD----QGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNI-------- 593
             + GEKG+    +G  G+ G PG++G  G KG  G+PG PG +G+PG  G +        
Sbjct: 536  -LKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGD 594

Query: 594  -------GSPGYPGRQGLA-----GPEGNPGPKGAQGFIGSPGEAGQLGPEGE------- 634
                   GSPG PG  G A     GP+G PG +G QG  G+PG  G+ GP GE       
Sbjct: 595  QGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPV 654

Query: 635  ---RGIPGIRGKKGFKGRQGFPGDFGDRGPAGL---DGSPGL--VGGTGPP------GFP 680
                G PG  G  G +G  G PG  G  G  GL   DG PG+  +G  GPP      GFP
Sbjct: 655  PGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFP 714

Query: 681  GLRGSVGPVGPIGPAGIPGPMGLSGNKGL--------PGIKGDKGEQGTAGELGEPGYPG 732
            G +GS+G  G +G  G+PG  GL G KG         PG  G  GE+G +GE GE G P 
Sbjct: 715  GTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLP- 773

Query: 733  DKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGP--EGFPGDIGIPGQNGPEGPKGL 790
              G  GLPG PG  G  GP G  G PG  G  GPPG   EG  G  G+PG NG +G +G 
Sbjct: 774  --GLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGR 831

Query: 791  LGNRGPPGPPGLKGTQ-----GEEGPIGAFGELGPRGKPGQKGYAGEP---GPEGLKGEV 842
             G  GP G PG+ G       GE G  G  G  G  G  GQ+GY G P   GP G  G +
Sbjct: 832  RGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVI 891

Query: 843  GDQGNIGKIGETGPVGLPGEVGMTGS---------------IGEKGERGSPGP------L 881
            G  G  G IG  GP G PG  G  GS                GE+G++G+PGP      +
Sbjct: 892  GMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVI 951

Query: 882  GPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQ 941
            G +GE G+ G+ G PG  G  G  G+PG  G +G PG  GP G RG  G  G  GE G++
Sbjct: 952  GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011

Query: 942  GAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGL-----------------PGSTG 984
            G  G  G+ G  G  G  G  G PG  G  G PG+ GL                 PG TG
Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071

Query: 985  DRGLPGEPGLRGLQGDVGPPGEMGMEGP---PGTEGESGLQGEPGAKGDVGTAGSVGGTG 1041
            D GLPG+ G +G  G  GPPG +G  GP   PG+ G  GL G+PG  GD+G  G  G  G
Sbjct: 1072 DPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLG 1131

Query: 1042 EPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMG-LPGIIGPLGRSGQTGLP 1100
             PG+RG PG PG  G  G  G++G  G  G+PG  GEKGE G L    GP G  G  G  
Sbjct: 1132 PPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAK 1191

Query: 1101 GPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGK--SGPKGARGTRGAVGHLG 1158
            G  G  G PG  GR G  GD G  GPTG  G  GPPG  G    G  G RG  G+ G  G
Sbjct: 1192 GDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPG 1251

Query: 1159 LMGPDGEP-----GIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVG 1213
              GP G P     GI G +G  G PGP G PG  G+ G PG     LG PG  G PGP G
Sbjct: 1252 APGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR----LGAPGTPGLPGPRG 1307

Query: 1214 DQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPG 1273
            D G +G PG +G KG+   PG  G+    GPPG  G +G  G++G+ G+       G+PG
Sbjct: 1308 DPGFQGFPGVKGEKGN---PGFLGSI---GPPGPIGPKGPPGVRGDPGTLKIISLPGSPG 1361

Query: 1274 PSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPG 1333
            P G PG PG+QG  GP G                  PPG  G  G RG PG+ G  G PG
Sbjct: 1362 PPGTPGEPGMQGEPGPPG------------------PPGNLGPCGPRGKPGKDGKPGTPG 1403

Query: 1334 PPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGA 1373
            P G KG+ G  G P   GP G  GL   PG++GKRG  G+
Sbjct: 1404 PAGEKGNKGSKGEP---GPAGSDGL---PGLKGKRGDSGS 1437



 Score =  609 bits (1570), Expect = e-174
 Identities = 364/831 (43%), Positives = 428/831 (51%), Gaps = 92/831 (11%)

Query: 489  GPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGL--PGPKGPKGDPGFSPGQP 546
            GP G  G PGP GP GIPG  GK G  G+PGP G PG+PG+  PGP GPKGD GF     
Sbjct: 659  GPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGF----- 713

Query: 547  VPGEKGDQGLSGLMGPPGMQGDKGLKGH-----------PGLPGLPGEQGIPGFAGNIGS 595
             PG KG  G  G MG PG+ G  GL G            PG PG PGE+G  G  G IG 
Sbjct: 714  -PGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGL 772

Query: 596  PGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLG-----PEGERGIPGIRGKKGFKGRQ 650
            PG PG  G  G EG  GP+G  G  G PGE G  G     P G +G+PG+ G KG +GR+
Sbjct: 773  PGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRR 832

Query: 651  GFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLP 710
            G  G  GD G  GLD S G  G TG PG PG +G +GP+G  G  G PG +G  G  G+ 
Sbjct: 833  GKTGPKGDPGIPGLDRS-GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVI 891

Query: 711  GIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPS------ 764
            G+ G  G  G  G  G PG PG +G+ G+PG  G RG  G  G+ GD G  GPS      
Sbjct: 892  GMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVI 951

Query: 765  ---GPPGPEGFPGDIG------------------IPGQNGPEGPKGLLGNRGPPGPPGLK 803
               G PG +GF G+ G                  +PG  GP GP+G LG+ G PG PGL+
Sbjct: 952  GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011

Query: 804  GTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKI--------GETG 855
            G  G  G +G  G  G RG  G  G AG PG  G+ G  GD+G  G          G TG
Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071

Query: 856  PVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARG 915
              GLPG++G  G +G+ G  G  GP GP+G  G  G PG PG PGP G LG  G  G  G
Sbjct: 1072 DPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLG 1131

Query: 916  PPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPG 975
            PPG +GP G  G  G  G +G +G QG  G  G  G++G  GL+     PG RG    PG
Sbjct: 1132 PPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLL--RAPPGPRG---NPG 1186

Query: 976  LQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAG 1035
             QG  G  G  G PG PG +G  GD GP G  G+EG PG          PG  G +   G
Sbjct: 1187 AQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGP---------PGLPGAI-IPG 1236

Query: 1036 SVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSG 1095
              G  G PG RG PGAPG  G  G   + G+ G +G  G  G KG  G  G +GP GR G
Sbjct: 1237 QTGNRGPPGSRGSPGAPGPPGPPGSHVI-GIKGDKGSMGHPGPKGPPGTAGDMGPPGRLG 1295

Query: 1096 QTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVG 1155
              G PG  G  G PG +G PG KG+KG     G +GS GPPG IG  GP G RG  G + 
Sbjct: 1296 APGTPGLPGPRGDPGFQGFPGVKGEKGN---PGFLGSIGPPGPIGPKGPPGVRGDPGTLK 1352

Query: 1156 HLGLMGPDGEPGIPGYRGHQGQPGPSGLPG---PKGEKGYPGEDSTVLGPPGPRGEPGPV 1212
             + L G  G PG PG  G QG+PGP G PG   P G +G PG+D          G+PG  
Sbjct: 1353 IISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKD----------GKPGTP 1402

Query: 1213 GDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSE 1263
            G  GE+G  G++G  G  G  GL G  G++G  G P     +G    R S+
Sbjct: 1403 GPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQ 1453



 Score =  504 bits (1298), Expect = e-142
 Identities = 304/700 (43%), Positives = 365/700 (52%), Gaps = 59/700 (8%)

Query: 485  EYLRGPKGDTGPPGPPGPAGIPGP--SGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFS 542
            E L GP+GD G PGPPG  G PG    G RG +G+PG +G  G  G  G  GPKGDPG  
Sbjct: 785  EGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGI- 843

Query: 543  PG---QPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGI---PGFAGNIGSP 596
            PG      PGE G  G+ G  G  G  G +G  G+PG+ G PGE G+    GF G IG P
Sbjct: 844  PGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPP 903

Query: 597  GYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERG------IPGIRGKKGFKGRQ 650
            G PG  G  G  G+PG  G +G  G+PG  G+ G +G  G      + G +G+ G KG  
Sbjct: 904  GPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFA 963

Query: 651  GFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLP 710
            G PG+ G+RG  G+ G  GL G  GP G PG RG +G  G  G  G+ G  G  GN G+P
Sbjct: 964  GNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMP 1023

Query: 711  GIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRG--KSGPSGQTGDPGLQGPSGPPG 768
            G KG +G  G  G  G PG PG  G  G  G PG     + GP G TGDPGL G  G  G
Sbjct: 1024 GSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKG 1083

Query: 769  PEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGP---RGKPG 825
              G PG    PG  GP GP+G  G+ G PG PG  G  G+ G  G  G LGP   RG PG
Sbjct: 1084 EMGQPGP---PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPG 1140

Query: 826  QKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGL----PGEVGMTGSIGEKGERGSPG-- 879
              G+ G PGP G++G+ G  G  G  GE G  GL    PG  G  G+ G KG+RG+PG  
Sbjct: 1141 LPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFP 1200

Query: 880  ----------PLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSR 929
                        GP+G  G+ G+PGPPG+PG I    +PG  G RGPPGS+G  G  G  
Sbjct: 1201 GLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI----IPGQTGNRGPPGSRGSPGAPGPP 1256

Query: 930  GPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLP 989
            GP G      + G KG+KG  G  GP G  G  G+ G  G  G PG  GLPG  GD G  
Sbjct: 1257 GPPG----SHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQ 1312

Query: 990  GEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEP 1049
            G PG++G +G+   PG +G  GPPG  G    +G PG +GD GT   +   G P   G P
Sbjct: 1313 GFPGVKGEKGN---PGFLGSIGPPGPIGP---KGPPGVRGDPGTLKIISLPGSP---GPP 1363

Query: 1050 GAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGL---PGPEGIV 1106
            G PGE G+QG+ G  G PG  G  G  G+ G+ G PG  GP G  G  G    PGP G  
Sbjct: 1364 GTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSD 1423

Query: 1107 GIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKG 1146
            G+PG +G+ G  G        G V +R        S P+G
Sbjct: 1424 GLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEG 1463



 Score =  394 bits (1012), Expect = e-109
 Identities = 257/653 (39%), Positives = 318/653 (48%), Gaps = 97/653 (14%)

Query: 913  ARGPPGSQG----PKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGER 968
            A  P  S+G     KGQ    G  G  GE+G  G  G  G +G  GP GL      PG +
Sbjct: 22   AAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGL------PGPQ 75

Query: 969  GFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAK 1028
            G +G PGL GL GS G RG+ G PG  G  G  G PG  G  G  G  G SG +GE G  
Sbjct: 76   GPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFP 135

Query: 1029 GDVGTAGSVGGTGEPGLRGEPGAPGEE-----GLQGKDGLKGVPGGRGLPGEDGEKGEMG 1083
            G  GT G  G  G  GL+G+ GAP +E       +G  GL G PG +GLPG  G  G +G
Sbjct: 136  GLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVG 195

Query: 1084 LPGIIGPLGRSGQTGLPGPEGIVG--IPGQRGRPGKKGDKGQIGPTGEV----------- 1130
             PG  G  G  G  G  GP+G +G  + G +G  G KG  G  GP G V           
Sbjct: 196  PPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRT 255

Query: 1131 ---GSRGPPGKIGKSGPKGARGT--------RGAVGHLGLMGPDGEPGIPGYRGHQGQPG 1179
               G +G  G +G+ GP G  G         +GA G  GL G  G+ G+PG+ G +G  G
Sbjct: 256  DLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG 315

Query: 1180 PSGLPGPKGEKGYPGE-----------------------DSTVLGPPGPRGEPGPVGDQG 1216
              G PG  GE G  G+                       D    GPPGPRG  GP G  G
Sbjct: 316  NRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSG 375

Query: 1217 ERGEPGAEG-----YKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGA 1271
              G PG+ G      +G  G PGL+G+ G++G PG+    G  G  G  GS G  G  G 
Sbjct: 376  PPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDA-MGTPGSPGCAGSPGLPGSPGP 434

Query: 1272 PGPSG----KPGIPGLQGLLGPKGIQGYHGADGISGNPGKI--------GPPGKQGLPG- 1318
            PGP G    + G PG  GL G  G  G  G DG  G PG +        GPPG  GLPG 
Sbjct: 435  PGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGL 494

Query: 1319 --IRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHR-GAQG 1375
              ++G PGR G AG  G PG  G++GLPG PG  G +G+      PG++G++G     +G
Sbjct: 495  HGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGD------PGLKGEKGETLQPEG 548

Query: 1376 DQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLG 1435
              G  GDPGL+GQPG  G+ G+ G  G  G  GP+G+  + G  G +GP G  G+ G  G
Sbjct: 549  QVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPG 608

Query: 1436 REGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQMDINAAI 1488
              G  GP G  GP+GE G       QG +G PG PGPPG  GPR ++ ++  +
Sbjct: 609  PAGPAGPPGY-GPQGEPGL------QGTQGVPGAPGPPGEAGPRGELSVSTPV 654



 Score =  335 bits (860), Expect = 2e-91
 Identities = 205/477 (42%), Positives = 235/477 (49%), Gaps = 53/477 (11%)

Query: 484  MEYLRGPKGDTGPPGPPGP------------------------AGIPGPSGKRGPRGIPG 519
            M  L+G KG  GP GPPGP                         G+PG  GKRG  G PG
Sbjct: 977  MPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036

Query: 520  PHGNPGLPGLPGPKGPKGDPGFS----PGQP----VPGEKGDQGLSGLMGPPGMQGDKGL 571
              G PGLPG+ G +G KG+PG+S    PG P     PG  GD G  G MG PG  G  G 
Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGP 1096

Query: 572  KGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGP 631
             G  G PG PG  G+PG  G  G  G+ G +GL GP G  GP G  GF GSPG  G  G 
Sbjct: 1097 AGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGD 1156

Query: 632  EGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGP 691
            +G  GIPG  G+KG  G    P   G RG  G  G+ G  G  G PG PG +G++G  GP
Sbjct: 1157 QGRDGIPGPAGEKGETGLLRAPP--GPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP 1214

Query: 692  IGPAGI---PGPMGL--------SGNKGLPGIKGDKGEQGTAGELGEP--GYPGDKGAVG 738
             GP GI   PGP GL        +GN+G PG +G  G  G  G  G    G  GDKG++G
Sbjct: 1215 RGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMG 1274

Query: 739  LPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPG 798
             PGP G  G +G  G  G  G  G  G PGP G PG  G PG  G +G  G LG+ GPPG
Sbjct: 1275 HPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPG 1334

Query: 799  PPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVG 858
            P G KG  G  G  G    +   G PG  G  GEPG +G  G  G  GN+G  G  G  G
Sbjct: 1335 PIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPG 1394

Query: 859  LPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARG 915
              G+ G  G  GEKG +GS G  GP G  G+      PG+ G  G  G P     RG
Sbjct: 1395 KDGKPGTPGPAGEKGNKGSKGEPGPAGSDGL------PGLKGKRGDSGSPATWTTRG 1445



 Score =  240 bits (613), Expect = 8e-63
 Identities = 143/336 (42%), Positives = 170/336 (50%), Gaps = 16/336 (4%)

Query: 475  YEDLNTMLEMEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPG-LPGPK 533
            ++ +  +L    +RGP G  G PG PGP GI G  G+    GIPGP G  G  G L  P 
Sbjct: 1123 FKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGR---DGIPGPAGEKGETGLLRAPP 1179

Query: 534  GPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPG--FAG 591
            GP+G+PG    Q   G++G  G  GL G  G  GD G +G  G+ G PG  G+PG    G
Sbjct: 1180 GPRGNPG---AQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPG 1236

Query: 592  NIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQG 651
              G+ G PG +G  G  G PGP G+   IG  G+ G +G  G +G PG  G  G  GR G
Sbjct: 1237 QTGNRGPPGSRGSPGAPGPPGPPGSH-VIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLG 1295

Query: 652  FPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPG 711
             PG  G  GP G  G  G  G  G  G PG  GS+GP GPIGP G PG  G  G   +  
Sbjct: 1296 APGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIIS 1355

Query: 712  IKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEG 771
            + G  G  GT      PG PG +G  G PGPPG  G  GP G+ G  G  G  GP G +G
Sbjct: 1356 LPGSPGPPGT------PGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409

Query: 772  FPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQG 807
              G  G PG  G +G  GL G RG  G P    T+G
Sbjct: 1410 NKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1637

 Score =  767 bits (1981), Expect = 0.0
 Identities = 499/1206 (41%), Positives = 582/1206 (48%), Gaps = 239/1206 (19%)

Query: 491  KGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGE 550
            KGD G PG PGP G+PGP G  GP G PGP G  G PG  GP+GPKG  G    + V G 
Sbjct: 170  KGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMG----ERVIGH 225

Query: 551  KGDQGLSGLMGPPG-----------------MQGDKGLKGHPGLPGLPGEQGIPG--FAG 591
            KG++G+ GL GPPG                 ++G+KG KG  G PG PG  G+PG  +  
Sbjct: 226  KGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGS 285

Query: 592  NIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQG 651
              G+PG PG QG  G +G PG  G++G             +G RG PG+ G+ G KG++G
Sbjct: 286  EKGAPGDPGLQGKPGKDGVPGFPGSEGV------------KGNRGFPGLMGEDGIKGQKG 333

Query: 652  FPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMG-----LSGN 706
              G  G RGP     +    G  G PG PG RG+ GP GP GP G+PG  G     L G 
Sbjct: 334  DIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGA 393

Query: 707  KGLPGIKGDKGEQGTAGE--LGEPGYPGDKGAVGLPG----------------PPGMRGK 748
             G PG+KG KGE+G  G+  +G PG PG  G+ GLPG                PPG  G 
Sbjct: 394  PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGL 453

Query: 749  SGPSGQTGDPGLQGPSG--------------PPGPEGFPGDIGIPGQNGPEGPKGLLGNR 794
             G  G  G PG+ GP G              PPG  G PG  G+ G  G +G  GL G+ 
Sbjct: 454  PGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSP 513

Query: 795  GPPG---------------PPGLKGTQGE----EGPIGAFGELGPRGKPGQKGYAGEPGP 835
            G PG                PGLKG +GE    EG +G  G+ G RG+PG+KG  G PG 
Sbjct: 514  GSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGT 573

Query: 836  EGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGE------KGV 889
             G+KG  G +G +   GE G  G PG+ G  GS G  G  G PG  GPQGE      +GV
Sbjct: 574  PGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGTQGV 632

Query: 890  MGYPGPPG-------------VPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRG------ 930
             G PGPPG             VPGP GP G PGH G +GPPG  G  G+ G  G      
Sbjct: 633  PGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDG 692

Query: 931  -----------PDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPG------------- 966
                       P G  G+QG  G KG  G  GK G  GL GK G PG             
Sbjct: 693  EPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP 752

Query: 967  -------ERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGT--EG 1017
                   ERG  G+ G  GLPG  G  G PG  GL G +GD G PG  G +GPPG   EG
Sbjct: 753  GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812

Query: 1018 ESGLQGEPGA---KGDVGTAGSVGGTGEPGL-----------RGEPGAPGEEGLQGKDGL 1063
              G QG PG    KG  G  G  G  G+PG+            G PG PG +G  G  G 
Sbjct: 813  PRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ 872

Query: 1064 KGVPGGRGL---PGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPG---QRGRPGK 1117
            +G PG  G+   PGEDG  G MG PG IGP G  G  G PG  G  GIPG   QRG PG 
Sbjct: 873  RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932

Query: 1118 KG---DKGQIGPT---------------------GEVGSRGPPGKIGKSGPKGARGTRGA 1153
            KG   DKG  GP+                     GE G+RG PG  G  G KG  G  G 
Sbjct: 933  KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992

Query: 1154 VGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKG---YPGE--------------- 1195
             G  G +G  G PG PG RG  G  G  G+PG KG++G   +PG                
Sbjct: 993  PGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGD 1052

Query: 1196 -------DSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEP 1248
                   + T  GPPGP G+PG  GD G++GE G  G  GH+G  G  GA G  G PG P
Sbjct: 1053 KGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLP 1112

Query: 1249 GDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKI 1308
            G  G  G   + G +G KG  G PG  G PG+PG  G  GP GI+G  G DGI G  G+ 
Sbjct: 1113 GKPGPHG---DLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEK 1169

Query: 1309 G-------PPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQ 1361
            G       PPG +G PG +G  G  G   APG PG+ G  G  G  G +GP G +G PG 
Sbjct: 1170 GETGLLRAPPGPRGNPGAQGAKGDRG---APGFPGLPGRKGAMGDAGPRGPTGIEGFPGP 1226

Query: 1362 PG-----IQGKRGHRGAQGDQGPCGDPGLKGQPGEY--GVQGLTGFQGFPGPKGPEGDAG 1414
            PG     I G+ G+RG  G +G  G PG  G PG +  G++G  G  G PGPKGP G AG
Sbjct: 1227 PGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286

Query: 1415 IVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPG 1474
             +G  G  G  G  G  GP G  G  G  G  G +G  GF G  GP GP G  GPPG  G
Sbjct: 1287 DMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRG 1346

Query: 1475 APGPRK 1480
             PG  K
Sbjct: 1347 DPGTLK 1352



 Score =  754 bits (1947), Expect = 0.0
 Identities = 490/1176 (41%), Positives = 578/1176 (49%), Gaps = 189/1176 (16%)

Query: 488  RGPKGDTGPPGPPGPAGIPGPS--------------GKRGPRGIPG------PHGNPGLP 527
            +G KG  G PGPPGP+G+PG S              GK G  G+PG        GN G P
Sbjct: 261  KGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFP 320

Query: 528  GLPGP---KGPKGD---PGF-----------------SPGQPVP-GEKGDQGLSGLMGPP 563
            GL G    KG KGD   PGF                 +PG P P G +G QG SG  G P
Sbjct: 321  GLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVP 380

Query: 564  GMQGDK--GLKGHPGLPGLPGEQG-----------IPGFAGNIGSPGYPGRQGLAGPEGN 610
            G  G    GL+G PG PGL G +G            PG  G  GSPG PG  G  GP G+
Sbjct: 381  GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGD 440

Query: 611  -------PGPKGAQGFIGSPGEAGQLGPEGERG--------IPGIRGKKGFKGRQGFPGD 655
                   PG  G  G++GSPG  G  GP+GE G        IPG  G  G  G  G  G 
Sbjct: 441  IVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGI 500

Query: 656  FGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVG-------------PVGPIGPAGIPGPMG 702
             G +G AGL GSPG  G TG PGFPG  G+ G             P G +G  G PG  G
Sbjct: 501  PGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRG 560

Query: 703  LSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQG 762
              G KGL GI G  G +G  G  GE    G+KG  G PG PG  G  GP+G  G PG  G
Sbjct: 561  QPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY-G 619

Query: 763  PSGPPGPEGFPGDIGIPGQNGPEGPKGLL-------GNRGPPGPPGLKGTQGEEGPIGAF 815
            P G PG +G  G  G PG  G  GP+G L       G  GPPGPPG  G QG  G  G+ 
Sbjct: 620  PQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSL 679

Query: 816  GELGPRGKPGQKG--------YAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTG 867
            G+ G  G PG  G        + G PGP+G +G  G +G++G  G+ G  GLPG+ G+ G
Sbjct: 680  GKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPG 739

Query: 868  SIGEK--------GERGSPGPLGPQGEKGVMGYPGPPGVPG---------PIGPLGLPGH 910
            + GE         G  G PG  G  GE G +G PG PG+PG         P G  G PG 
Sbjct: 740  AKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGP 799

Query: 911  VGARGPPGS--QGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRG--PHGLIGKTGNPG 966
             G +GPPG   +GP+G +G  G +GL G+QG +G  G KGD G  G    G  G+TG+PG
Sbjct: 800  PGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPG 859

Query: 967  ------------ERGFQGKPGL------------QGLPGSTGDRGLPGEPGLRGLQGDVG 1002
                        +RG+ G PG+             G PG+ G  G PG PG  G +G  G
Sbjct: 860  IPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPG 919

Query: 1003 PPGEMGMEGPPGTEGESGLQGEPGA---------KGDVGTAGSVGGTGEPGLRGEPGAPG 1053
             PG  G  G PG +GE G +G PG          KG+ G  G  G  GE G RG PG PG
Sbjct: 920  IPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPG 979

Query: 1054 EEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRG 1113
             +GL+G  G  G PG RG  G  G  GE GL GI G +G  G  G  G  G +G PG+ G
Sbjct: 980  LKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAG 1039

Query: 1114 RPGK------KGDKGQIGPT-----GEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGP 1162
            RPG       +GDKG+ G +     G  G  G PG  G  G KG  G  G  GHLG  GP
Sbjct: 1040 RPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGP 1099

Query: 1163 DGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRG---EPGPVG---DQG 1216
            +G PG PG  G  G+PGP G  G KG KG  G    + GPPG  G    PGP+G   DQG
Sbjct: 1100 EGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPG-IRGPPGLPGFPGSPGPMGIRGDQG 1158

Query: 1217 ERGEPGAEGYKGHVGV----PGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAP 1272
              G PG  G KG  G+    PG RG  G QG  G+ G  G  GL G +G+ G+ G +G  
Sbjct: 1159 RDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPT 1218

Query: 1273 GPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQG--LPGIRGGPGRTGLAG 1330
            G  G PG PGL G + P G  G  G  G  G+PG  GPPG  G  + GI+G  G  G  G
Sbjct: 1219 GIEGFPGPPGLPGAIIP-GQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPG 1277

Query: 1331 APGPPGVKGSSG------LPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPG 1384
              GPPG  G  G       PG+PG+ GP+G+ G  G PG++G++G+ G  G  GP G  G
Sbjct: 1278 PKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIG 1337

Query: 1385 LKGQPGEYGVQG---LTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIG 1441
             KG PG  G  G   +    G PGP G  G+ G+ G  GP GP G+ G  GP G+ G  G
Sbjct: 1338 PKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDG 1397

Query: 1442 PTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPG 1477
              G  GP GEKG +G  G  GP G  G PG  G  G
Sbjct: 1398 KPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433



 Score =  754 bits (1946), Expect = 0.0
 Identities = 509/1309 (38%), Positives = 597/1309 (45%), Gaps = 329/1309 (25%)

Query: 489  GPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGD------PGFS 542
            G KG+ G  G PGP G PG  G  GP G+PGP G  G PGLPG  G KG       PGFS
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 543  PGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFA------------ 590
                +PG  G+ G  GL+G PG  G KG +G PGLPG  G  GIPG A            
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 591  --------GNIGSPGYPGRQGLAGPEGNP---GPKGAQGFIGSPGEAGQLGP-------- 631
                    G+ G PG PG QGL GP G P   GP G  GF G PG  G  GP        
Sbjct: 163  EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERV 222

Query: 632  ---EGERGIPGIRGKKG-----------------FKGRQGFPGDFGDRGPAGLDGSPGLV 671
               +GERG+ G+ G  G                  KG +G  G  G+ GP G  G PG  
Sbjct: 223  IGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGES 282

Query: 672  GGT--GPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPG 729
             G+  G PG PGL+G     G  G  G PG  G+ GN+G PG+ G+ G +G  G++G PG
Sbjct: 283  YGSEKGAPGDPGLQGK---PGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPG 339

Query: 730  YPG---------DKGAVGLPGPPGMRGKSGPSGQTGDPGLQGP----------------- 763
            + G         +KG  G PGPPG RG  GP G +G PG+ G                  
Sbjct: 340  FRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGL 399

Query: 764  -----------------------------SGPPGPEGFPGDI------------------ 776
                                          G PGP G PGDI                  
Sbjct: 400  KGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGS 459

Query: 777  -GIPGQNGPEGPKGLLGNR-----GPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYA 830
             GIPG +GP+G  GLL  +     GPPG PGL G  G +G  G  G  G +G PG  G  
Sbjct: 460  PGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNT 519

Query: 831  GEPGPEGLKGEVGDQGNIGKIGET----GPVGLPGEVGMTGSIGEK-------------- 872
            G PG  G  G  GD G  G+ GET    G VG+PG+ G+ G  G K              
Sbjct: 520  GLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGL 579

Query: 873  ----------------------GERGSPGPLGP--------------QGEKGVMGYPGPP 896
                                  G  GSPGP GP              QG +GV G PGPP
Sbjct: 580  PGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPP 639

Query: 897  G-------------VPGPIGPLGLPGHVGARGP---PGSQGPKGQRGSRGPDGLLGEQGI 940
            G             VPGP GP G PGH G +GP   PGS G  G  G  GPDG  G  GI
Sbjct: 640  GEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI 699

Query: 941  --QGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQG--------LPGSTGDRGLPG 990
               G  G KGDQG  G  G +G  G  GE G  GKPGL G        +PG  G  G PG
Sbjct: 700  GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 991  EPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSV--------GGTGE 1042
            E G  G  G++G PG  G+ G PG EG  G +G+PG  G  G  G          G  G 
Sbjct: 760  ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819

Query: 1043 PGL---------------RGEPGAPG--EEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLP 1085
            PGL               +G+PG PG    G  G+ G  G+PG +G  G  G++G  G P
Sbjct: 820  PGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNP 879

Query: 1086 GIIGPLGRSGQTGL---------PGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPP 1136
            GI+GP G  G  G+         PGP G  G PGQRG PG  G KGQ G  G  G +G  
Sbjct: 880  GILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDK 939

Query: 1137 GKIGKS------GPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEK 1190
            G  G S      G KG  G +G  G+ G  G  G PG+PG +G +G PGP+G PGP+G+ 
Sbjct: 940  GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999

Query: 1191 GYPGEDSTVLGPPGPRGEPGPVGDQ---GERGEPGAEGYKGHVGVPGLRGATGQQGP--- 1244
            G  G      G PG RG PG +G+    G +G+ G  G+ G  G PGL G  G QG    
Sbjct: 1000 GSTGNP----GEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE 1055

Query: 1245 --------PGEPGDQGEQGLKGERGSEGNKGKKGAP---------GPSGKPGIPGLQGLL 1287
                    PG PG  G+ GL G+ G +G  G+ G P         G  G PG PGL G  
Sbjct: 1056 PGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKP 1115

Query: 1288 GPKGIQGYHGADGISGNPGKIGPPGKQGLP------GIRGGPGRTGLAGAPGPPGVKGSS 1341
            GP G  G+ G  G+ G PG  GPPG  G P      GIRG  GR G+   PGP G KG +
Sbjct: 1116 GPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGI---PGPAGEKGET 1172

Query: 1342 GL-------PGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPC------GDPGL--- 1385
            GL        G+PG QG KG++G PG PG+ G++G  G  G +GP       G PGL   
Sbjct: 1173 GLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGA 1232

Query: 1386 --KGQPGEYGVQGLTGFQGFPGPKGP--------EGDAGIVGISGPKGPIGHRGNTGPLG 1435
               GQ G  G  G  G  G PGP GP        +GD G +G  GPKGP G  G+ GP G
Sbjct: 1233 IIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPG 1292

Query: 1436 REGIIGPTGRTGPRGEKGFRGETGPQGPRGQP------GPPGPPGAPGP 1478
            R G  G  G  GPRG+ GF+G  G +G +G P      GPPGP G  GP
Sbjct: 1293 RLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGP 1341



 Score =  748 bits (1931), Expect = 0.0
 Identities = 484/1192 (40%), Positives = 581/1192 (48%), Gaps = 205/1192 (17%)

Query: 485  EYLRGPKGDTGPPGPPGPAGIPGP-----SGKRGPRGIPGPHGNPGLPGLPGPKGPKGDP 539
            E + G KG+ G  G  GP G PG      +G      + G  G+ G  G PGP GP G P
Sbjct: 220  ERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLP 279

Query: 540  GFSPG--QPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPG 597
            G S G  +  PG+ G QG  G  G PG  G +G+KG+ G PGL GE GI G  G+IG PG
Sbjct: 280  GESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPG 339

Query: 598  Y------------PGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPE--GERGIPGIRGK 643
            +             G +G  GP G  G +G QG  G PG  G  G    G RG PG  G 
Sbjct: 340  FRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGL 399

Query: 644  KGFKGRQGFPGD--FGDRGPAGLDGSPGLVGGTGPP----------------GFPGLRGS 685
            KG KG +G PG    G  G  G  GSPGL G  GPP                G PG  GS
Sbjct: 400  KGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGS 459

Query: 686  VGPVGPIGPAG-----------IPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDK 734
             G  G  GP G           IPGP GL G  GL G+KG  G QG AG  G PG PG+ 
Sbjct: 460  PGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNT 519

Query: 735  GAVGLPGPPGMRGKSG----------PSGQT---GDPGLQGPSGPPGPEGFPGDIGIPGQ 781
            G  G PG PG +G  G          P GQ    GDPGL+G  G  G +G PG  G+ G 
Sbjct: 520  GLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGL 579

Query: 782  NGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGE--LGPRGKPGQKGYAGEPGPEGLK 839
             GP+G   L G +G  GPPG  G+ G  GP G  G    GP+G+PG +G  G PG  G  
Sbjct: 580  PGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPP 639

Query: 840  GEVGDQGNI-------GKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGV--M 890
            GE G +G +       G  G  GP G PG  G  G  G  G+ G PG  GP GE G+  +
Sbjct: 640  GEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI 699

Query: 891  GYPGPP------GVPGPIGPLGLPGHVG--------------------ARGPPGSQGPKG 924
            G+PGPP      G PG  G LG PG +G                      G PG+ G  G
Sbjct: 700  GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 925  QRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGE-----------RGFQGK 973
            +RG+ G  G +G  G+ G  G  G++G  GP G  G+ G PGE           RG QG 
Sbjct: 760  ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819

Query: 974  PGLQGLPGSTGDR-----------------GLPGE---PGLRGLQGDVGP------PGEM 1007
            PGL GL G  G R                 G PGE   PG+ G QG++GP      PG  
Sbjct: 820  PGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNP 879

Query: 1008 GMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVP 1067
            G+ GPPG +G  G+ G PGA   +G  G  G  G PG RG PG PG +G +G  G KG  
Sbjct: 880  GILGPPGEDGVIGMMGFPGA---IGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQ 936

Query: 1068 GGRGLPGED------GEKGEMGLPGIIGPLGRSGQ---TGLPGPEGIVGIPGQRGRPGKK 1118
            G +G PG        G+KGE GL G  G  G  G     G+PG +G+ G+PG  G PG +
Sbjct: 937  GDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPR 996

Query: 1119 GDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQP 1178
            GD G  G  GE G RG PG +G  G  G++G RG +G  G  G  G PGI G +G +G+P
Sbjct: 997  GDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056

Query: 1179 GPS-----GLPGPKGEKGYPGEDSTV-----------LGPPGPRGEPGPVGDQGERGEPG 1222
            G S     G PGP G+ G PG+               LGP GP G PG  G  G  G+PG
Sbjct: 1057 GYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPG 1116

Query: 1223 AEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPG 1282
              G  G  G+ GL G  G +GPPG PG  G  G  G R   G++G+ G PGP+G+ G  G
Sbjct: 1117 PHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIR---GDQGRDGIPGPAGEKGETG 1173

Query: 1283 -LQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSS 1341
             L+   GP+G  G  GA G  G PG  G PG++G  G  G  G TG+ G PGPPG+ G+ 
Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233

Query: 1342 GLPGSPGIQGPKGEQGLPGQPG--------IQGKRGHRGAQGDQGPCGDPGLKGQ----- 1388
             +PG  G +GP G +G PG PG        + G +G +G+ G  GP G PG  G      
Sbjct: 1234 -IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPG 1292

Query: 1389 -------PGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGII- 1440
                   PG  G +G  GFQGFPG KG +G+ G +G  GP GPIG +G  G  G  G + 
Sbjct: 1293 RLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLK 1352

Query: 1441 -----GPTGRTGPRGEKGFRGETGPQ---------GPRGQPGPPGPPGAPGP 1478
                 G  G  G  GE G +GE GP          GPRG+PG  G PG PGP
Sbjct: 1353 IISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGP 1404



 Score =  733 bits (1891), Expect = 0.0
 Identities = 475/1108 (42%), Positives = 550/1108 (49%), Gaps = 171/1108 (15%)

Query: 491  KGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGN--------PGLPGLPGPKGPKGDPGF- 541
            KGD G PGPPGP G  GP G  GP G+PG  G+        PG PGL G KG +G PG  
Sbjct: 353  KGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKD 412

Query: 542  ------------------SPGQPVP--------GEKGDQGLSGLMGPPGMQGDKGLKGHP 575
                              SPG P P        G  GD GL G +G PG+ G  G KG P
Sbjct: 413  AMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEP 472

Query: 576  GL-----PGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLG 630
            GL     P +PG  G+PG  G  G  G PGRQG AG +G+PG  G  G  G PG  G  G
Sbjct: 473  GLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQG 532

Query: 631  -------------PEGERGIPG---IRGKKGFKGRQGFPGDFGDRGPAGLDGS---PGLV 671
                         PEG+ G+PG   +RG+ G KG  G PG  G +G  G  G     G  
Sbjct: 533  DPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEK 592

Query: 672  GGTGPPGFPGLRGSVGPVGPIGPAGI--PGPMGLSGNKGLPGIKGDKGEQGTAGELGE-- 727
            G  GPPG PG  GS GP GP GP G    G  GL G +G+PG  G  GE G  GEL    
Sbjct: 593  GDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652

Query: 728  --PGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPG--------PEGFPGDIG 777
              PG PG  G  G PGP G  G  G  G+ GDPGL GP G PG        P G  GD G
Sbjct: 653  PVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQG 712

Query: 778  IPGQNGPEGPKGLLGNRGPPGPPGLKGTQGE-----------------EGPIGAFGELG- 819
             PG  G  G  G +G  G PG PGL G +GE                  G  G  GE+G 
Sbjct: 713  FPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGL 772

Query: 820  -----------------PRGKPGQKGYAGEPGP-----------EGLKGEVGDQGNIGKI 851
                             PRG PGQ G  GE GP           +GL G  G +G  G+ 
Sbjct: 773  PGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRR 832

Query: 852  GETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMG---YPGPPGVPGP------I 902
            G+TGP G PG  G+  S G  GE GSPG  G QGE G +G   YPG PG+ GP      I
Sbjct: 833  GKTGPKGDPGIPGLDRS-GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVI 891

Query: 903  GPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGL---I 959
            G +G PG +G  GPPG+ G  GQRGS G  G+ G++G  GAKGE+GD+G  GP  +   I
Sbjct: 892  GMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVI 951

Query: 960  GKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGES 1019
            G  G PG +GF G PG +   G+ G  G+PG  GL+GL G  GPPG  G  G  G  GE 
Sbjct: 952  GDKGEPGLKGFAGNPGEK---GNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEP 1008

Query: 1020 GLQGEPGAKGDVGTAGSVG--GT-GEPGLRGEPGAPGEEGLQG-----------KDGLKG 1065
            GL+G PG+ G++G  GS G  GT G PG  G PG PG  GLQG           + G  G
Sbjct: 1009 GLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG 1068

Query: 1066 VPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIG 1125
              G  GLPG+ G+KGEMG PG  G LG +G  G PG  G  G+PG+ G  G  G KG  G
Sbjct: 1069 PTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKG 1128

Query: 1126 PTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPG 1185
              G  G RGPPG  G  G  G  G RG  G  G+ GP GE G  G    +  PGP G PG
Sbjct: 1129 LLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLL--RAPPGPRGNPG 1186

Query: 1186 PKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPG--LRGATGQQG 1243
             +G KG    D    G PG  G  G +GD G RG  G EG+ G  G+PG  + G TG +G
Sbjct: 1187 AQGAKG----DRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRG 1242

Query: 1244 PPGEPGDQGEQGLKGERGSE--GNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGI 1301
            PPG  G  G  G  G  GS   G KG KG+ G  G  G PG  G +GP    G  GA G 
Sbjct: 1243 PPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP---PGRLGAPGT 1299

Query: 1302 SGNPGKIGPPGKQGLPGI---RGGPGRTGLAGAPGPPGVKGSSGLPGSPG------IQGP 1352
             G PG  G PG QG PG+   +G PG  G  G PGP G KG  G+ G PG      + G 
Sbjct: 1300 PGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGS 1359

Query: 1353 KGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGD 1412
             G  G PG+PG+QG+ G  G  G+ GPCG  G  G+ G+ G  G  G +G  G KG  G 
Sbjct: 1360 PGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGP 1419

Query: 1413 AGIVGISGPKGPIGHRGNTGPLGREGII 1440
            AG  G+ G KG  G  G+       G +
Sbjct: 1420 AGSDGLPGLKGKRGDSGSPATWTTRGFV 1447



 Score =  684 bits (1764), Expect = 0.0
 Identities = 438/1047 (41%), Positives = 525/1047 (50%), Gaps = 163/1047 (15%)

Query: 568  DKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAG 627
            DKG     G  G  GE+G PG       PG PG++G  GPEG PGP+G +GF G PG  G
Sbjct: 35   DKGQCFCDGAKGEKGEKGFPG------PPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTG 88

Query: 628  QLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVG 687
                   +G+ GI G  GF G  G PG  G+ GP GL G PG  G  G  GFPGL G+  
Sbjct: 89   S------KGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGT-- 140

Query: 688  PVGPIGPAGIPGPMGLSGNKGLPG--------IKGDKGEQGTAGELGEPGYPGDKGAVGL 739
                +G  GIPG  GL G KG P          KGD G  G  G  G PG PG  G VG 
Sbjct: 141  ----LGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP 196

Query: 740  PGPPGM------RGKSGPSGQTGDP--------GLQGPSGPPGPEG-----FPGDIGIPG 780
            PGPPG        G  GP G  G+         G++G +GPPGP G       G      
Sbjct: 197  PGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTD 256

Query: 781  QNGPEGPKGLLGNRGPPGPPGLKG-TQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLK 839
              G +G KG +G  GPPGP GL G + G E   GA G+ G +GKPG+ G  G PG EG+K
Sbjct: 257  LKGEKGDKGAMGEPGPPGPSGLPGESYGSEK--GAPGDPGLQGKPGKDGVPGFPGSEGVK 314

Query: 840  GE------VGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYP 893
            G       +G+ G  G+ G+ GP G  G      +  EKG+ G+PGP GP+G +G  G  
Sbjct: 315  GNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPS 374

Query: 894  GPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPD--------GLLGEQGIQGAKG 945
            GPPGVPG  G    PG  GA G PG +G KG+RG  G D        G  G  G+ G+ G
Sbjct: 375  GPPGVPGSPGS-SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPG 433

Query: 946  EKGDQG----KRGP---HGLIGKTGNPGERGFQGK-----------------PGLQGLPG 981
              G  G    ++GP   HGL G  G+PG  G  G                  PGL GLPG
Sbjct: 434  PPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493

Query: 982  STGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTA----GSV 1037
              G +G+PG  G  GL+G  G PG  G+   PG  G  G QG+PG KG+ G      G V
Sbjct: 494  LHGVKGIPGRQGAAGLKGSPGSPGNTGL---PGFPGFPGAQGDPGLKGEKGETLQPEGQV 550

Query: 1038 GGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRG---LPGEDGEKGEMGLPGIIGPLGRS 1094
            G  G+PGLRG+PG  G +G+ G  G+KG+PG +G   L GE G++G  G PG  G  G +
Sbjct: 551  GVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPA 610

Query: 1095 GQTGLPG--PEGIVGIPGQRGRPGKKGDKGQIGPTGEV----------GSRGPPGKIGKS 1142
            G  G PG  P+G  G+ G +G PG  G  G+ GP GE+          G  GPPG  G  
Sbjct: 611  GPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQ 670

Query: 1143 GPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSG------------LPGPKGEK 1190
            GP G  G+ G  G  GL GPDGEPGIPG  G  G PGP G             PG  GE 
Sbjct: 671  GPPGIPGSLGKCGDPGLPGPDGEPGIPGI-GFPGPPGPKGDQGFPGTKGSLGCPGKMGEP 729

Query: 1191 GYPGEDS----------TVLGPPGPRGEPGPVGDQGERGE------PGAEGYKGHVGVPG 1234
            G PG+             + G PG  G PG  G+ GE GE      PG  G  G+ G+ G
Sbjct: 730  GLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDG 789

Query: 1235 LRGATGQQGPPGEPGD--------QGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQ-- 1284
             RG  GQ GPPGE G         +G QGL G  G +G +G++G  GP G PGIPGL   
Sbjct: 790  PRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRS 849

Query: 1285 ---------GLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPP 1335
                     G+ G +G  G  G  G  GNPG +GPPG+ G+ G+ G P   G  G PGPP
Sbjct: 850  GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFP---GAIGPPGPP 906

Query: 1336 GVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQ---GPCGDPGLKGQPGEY 1392
            G  G+ G  GSPGI G KG++G PG  G QG +G+ G        G  G+PGLKG  G  
Sbjct: 907  GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP 966

Query: 1393 GVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEK 1452
            G +G  G  G PG KG +G  G  G  GP+G +G  GN G  G  GI G  G  G  G K
Sbjct: 967  GEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026

Query: 1453 GFRGETGPQGPRGQPGPPGPPGAPGPR 1479
            G RG  G  G  G+PG PG  G  G +
Sbjct: 1027 GKRGTLGFPGRAGRPGLPGIHGLQGDK 1053



 Score =  672 bits (1733), Expect = 0.0
 Identities = 425/1000 (42%), Positives = 500/1000 (50%), Gaps = 155/1000 (15%)

Query: 486  YLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQ 545
            Y+ GP G  G PG  G  GIPG  G  G +G PG  GN GLPG PG  G +GDPG     
Sbjct: 481  YIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPG----- 535

Query: 546  PVPGEKGD----QGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNI-------- 593
             + GEKG+    +G  G+ G PG++G  G KG  G+PG PG +G+PG  G +        
Sbjct: 536  -LKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGD 594

Query: 594  -------GSPGYPGRQGLA-----GPEGNPGPKGAQGFIGSPGEAGQLGPEGE------- 634
                   GSPG PG  G A     GP+G PG +G QG  G+PG  G+ GP GE       
Sbjct: 595  QGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPV 654

Query: 635  ---RGIPGIRGKKGFKGRQGFPGDFGDRGPAGL---DGSPGL--VGGTGPP------GFP 680
                G PG  G  G +G  G PG  G  G  GL   DG PG+  +G  GPP      GFP
Sbjct: 655  PGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFP 714

Query: 681  GLRGSVGPVGPIGPAGIPGPMGLSGNKGL--------PGIKGDKGEQGTAGELGEPGYPG 732
            G +GS+G  G +G  G+PG  GL G KG         PG  G  GE+G +GE GE G P 
Sbjct: 715  GTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLP- 773

Query: 733  DKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGP--EGFPGDIGIPGQNGPEGPKGL 790
              G  GLPG PG  G  GP G  G PG  G  GPPG   EG  G  G+PG NG +G +G 
Sbjct: 774  --GLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGR 831

Query: 791  LGNRGPPGPPGLKGTQ-----GEEGPIGAFGELGPRGKPGQKGYAGEP---GPEGLKGEV 842
             G  GP G PG+ G       GE G  G  G  G  G  GQ+GY G P   GP G  G +
Sbjct: 832  RGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVI 891

Query: 843  GDQGNIGKIGETGPVGLPGEVGMTGS---------------IGEKGERGSPGP------L 881
            G  G  G IG  GP G PG  G  GS                GE+G++G+PGP      +
Sbjct: 892  GMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVI 951

Query: 882  GPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQ 941
            G +GE G+ G+ G PG  G  G  G+PG  G +G PG  GP G RG  G  G  GE G++
Sbjct: 952  GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011

Query: 942  GAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGL-----------------PGSTG 984
            G  G  G+ G  G  G  G  G PG  G  G PG+ GL                 PG TG
Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071

Query: 985  DRGLPGEPGLRGLQGDVGPPGEMGMEGP---PGTEGESGLQGEPGAKGDVGTAGSVGGTG 1041
            D GLPG+ G +G  G  GPPG +G  GP   PG+ G  GL G+PG  GD+G  G  G  G
Sbjct: 1072 DPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLG 1131

Query: 1042 EPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMG-LPGIIGPLGRSGQTGLP 1100
             PG+RG PG PG  G  G  G++G  G  G+PG  GEKGE G L    GP G  G  G  
Sbjct: 1132 PPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAK 1191

Query: 1101 GPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGK--SGPKGARGTRGAVGHLG 1158
            G  G  G PG  GR G  GD G  GPTG  G  GPPG  G    G  G RG  G+ G  G
Sbjct: 1192 GDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPG 1251

Query: 1159 LMGPDGEP-----GIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVG 1213
              GP G P     GI G +G  G PGP G PG  G+ G PG     LG PG  G PGP G
Sbjct: 1252 APGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR----LGAPGTPGLPGPRG 1307

Query: 1214 DQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPG 1273
            D G +G PG +G KG+   PG  G+    GPPG  G +G  G++G+ G+       G+PG
Sbjct: 1308 DPGFQGFPGVKGEKGN---PGFLGSI---GPPGPIGPKGPPGVRGDPGTLKIISLPGSPG 1361

Query: 1274 PSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPG 1333
            P G PG PG+QG  GP G                  PPG  G  G RG PG+ G  G PG
Sbjct: 1362 PPGTPGEPGMQGEPGPPG------------------PPGNLGPCGPRGKPGKDGKPGTPG 1403

Query: 1334 PPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGA 1373
            P G KG+ G  G P   GP G  GL   PG++GKRG  G+
Sbjct: 1404 PAGEKGNKGSKGEP---GPAGSDGL---PGLKGKRGDSGS 1437



 Score =  609 bits (1570), Expect = e-174
 Identities = 364/831 (43%), Positives = 428/831 (51%), Gaps = 92/831 (11%)

Query: 489  GPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGL--PGPKGPKGDPGFSPGQP 546
            GP G  G PGP GP GIPG  GK G  G+PGP G PG+PG+  PGP GPKGD GF     
Sbjct: 659  GPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGF----- 713

Query: 547  VPGEKGDQGLSGLMGPPGMQGDKGLKGH-----------PGLPGLPGEQGIPGFAGNIGS 595
             PG KG  G  G MG PG+ G  GL G            PG PG PGE+G  G  G IG 
Sbjct: 714  -PGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGL 772

Query: 596  PGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLG-----PEGERGIPGIRGKKGFKGRQ 650
            PG PG  G  G EG  GP+G  G  G PGE G  G     P G +G+PG+ G KG +GR+
Sbjct: 773  PGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRR 832

Query: 651  GFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLP 710
            G  G  GD G  GLD S G  G TG PG PG +G +GP+G  G  G PG +G  G  G+ 
Sbjct: 833  GKTGPKGDPGIPGLDRS-GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVI 891

Query: 711  GIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPS------ 764
            G+ G  G  G  G  G PG PG +G+ G+PG  G RG  G  G+ GD G  GPS      
Sbjct: 892  GMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVI 951

Query: 765  ---GPPGPEGFPGDIG------------------IPGQNGPEGPKGLLGNRGPPGPPGLK 803
               G PG +GF G+ G                  +PG  GP GP+G LG+ G PG PGL+
Sbjct: 952  GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011

Query: 804  GTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKI--------GETG 855
            G  G  G +G  G  G RG  G  G AG PG  G+ G  GD+G  G          G TG
Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071

Query: 856  PVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARG 915
              GLPG++G  G +G+ G  G  GP GP+G  G  G PG PG PGP G LG  G  G  G
Sbjct: 1072 DPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLG 1131

Query: 916  PPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPG 975
            PPG +GP G  G  G  G +G +G QG  G  G  G++G  GL+     PG RG    PG
Sbjct: 1132 PPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLL--RAPPGPRG---NPG 1186

Query: 976  LQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAG 1035
             QG  G  G  G PG PG +G  GD GP G  G+EG PG          PG  G +   G
Sbjct: 1187 AQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGP---------PGLPGAI-IPG 1236

Query: 1036 SVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSG 1095
              G  G PG RG PGAPG  G  G   + G+ G +G  G  G KG  G  G +GP GR G
Sbjct: 1237 QTGNRGPPGSRGSPGAPGPPGPPGSHVI-GIKGDKGSMGHPGPKGPPGTAGDMGPPGRLG 1295

Query: 1096 QTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVG 1155
              G PG  G  G PG +G PG KG+KG     G +GS GPPG IG  GP G RG  G + 
Sbjct: 1296 APGTPGLPGPRGDPGFQGFPGVKGEKGN---PGFLGSIGPPGPIGPKGPPGVRGDPGTLK 1352

Query: 1156 HLGLMGPDGEPGIPGYRGHQGQPGPSGLPG---PKGEKGYPGEDSTVLGPPGPRGEPGPV 1212
             + L G  G PG PG  G QG+PGP G PG   P G +G PG+D          G+PG  
Sbjct: 1353 IISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKD----------GKPGTP 1402

Query: 1213 GDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSE 1263
            G  GE+G  G++G  G  G  GL G  G++G  G P     +G    R S+
Sbjct: 1403 GPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQ 1453



 Score =  504 bits (1298), Expect = e-142
 Identities = 304/700 (43%), Positives = 365/700 (52%), Gaps = 59/700 (8%)

Query: 485  EYLRGPKGDTGPPGPPGPAGIPGP--SGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFS 542
            E L GP+GD G PGPPG  G PG    G RG +G+PG +G  G  G  G  GPKGDPG  
Sbjct: 785  EGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGI- 843

Query: 543  PG---QPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGI---PGFAGNIGSP 596
            PG      PGE G  G+ G  G  G  G +G  G+PG+ G PGE G+    GF G IG P
Sbjct: 844  PGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPP 903

Query: 597  GYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERG------IPGIRGKKGFKGRQ 650
            G PG  G  G  G+PG  G +G  G+PG  G+ G +G  G      + G +G+ G KG  
Sbjct: 904  GPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFA 963

Query: 651  GFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLP 710
            G PG+ G+RG  G+ G  GL G  GP G PG RG +G  G  G  G+ G  G  GN G+P
Sbjct: 964  GNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMP 1023

Query: 711  GIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRG--KSGPSGQTGDPGLQGPSGPPG 768
            G KG +G  G  G  G PG PG  G  G  G PG     + GP G TGDPGL G  G  G
Sbjct: 1024 GSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKG 1083

Query: 769  PEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGP---RGKPG 825
              G PG    PG  GP GP+G  G+ G PG PG  G  G+ G  G  G LGP   RG PG
Sbjct: 1084 EMGQPGP---PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPG 1140

Query: 826  QKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGL----PGEVGMTGSIGEKGERGSPG-- 879
              G+ G PGP G++G+ G  G  G  GE G  GL    PG  G  G+ G KG+RG+PG  
Sbjct: 1141 LPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFP 1200

Query: 880  ----------PLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSR 929
                        GP+G  G+ G+PGPPG+PG I    +PG  G RGPPGS+G  G  G  
Sbjct: 1201 GLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI----IPGQTGNRGPPGSRGSPGAPGPP 1256

Query: 930  GPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLP 989
            GP G      + G KG+KG  G  GP G  G  G+ G  G  G PG  GLPG  GD G  
Sbjct: 1257 GPPG----SHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQ 1312

Query: 990  GEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEP 1049
            G PG++G +G+   PG +G  GPPG  G    +G PG +GD GT   +   G P   G P
Sbjct: 1313 GFPGVKGEKGN---PGFLGSIGPPGPIGP---KGPPGVRGDPGTLKIISLPGSP---GPP 1363

Query: 1050 GAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGL---PGPEGIV 1106
            G PGE G+QG+ G  G PG  G  G  G+ G+ G PG  GP G  G  G    PGP G  
Sbjct: 1364 GTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSD 1423

Query: 1107 GIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKG 1146
            G+PG +G+ G  G        G V +R        S P+G
Sbjct: 1424 GLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEG 1463



 Score =  394 bits (1012), Expect = e-109
 Identities = 257/653 (39%), Positives = 318/653 (48%), Gaps = 97/653 (14%)

Query: 913  ARGPPGSQG----PKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGER 968
            A  P  S+G     KGQ    G  G  GE+G  G  G  G +G  GP GL      PG +
Sbjct: 22   AAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGL------PGPQ 75

Query: 969  GFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAK 1028
            G +G PGL GL GS G RG+ G PG  G  G  G PG  G  G  G  G SG +GE G  
Sbjct: 76   GPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFP 135

Query: 1029 GDVGTAGSVGGTGEPGLRGEPGAPGEE-----GLQGKDGLKGVPGGRGLPGEDGEKGEMG 1083
            G  GT G  G  G  GL+G+ GAP +E       +G  GL G PG +GLPG  G  G +G
Sbjct: 136  GLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVG 195

Query: 1084 LPGIIGPLGRSGQTGLPGPEGIVG--IPGQRGRPGKKGDKGQIGPTGEV----------- 1130
             PG  G  G  G  G  GP+G +G  + G +G  G KG  G  GP G V           
Sbjct: 196  PPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRT 255

Query: 1131 ---GSRGPPGKIGKSGPKGARGT--------RGAVGHLGLMGPDGEPGIPGYRGHQGQPG 1179
               G +G  G +G+ GP G  G         +GA G  GL G  G+ G+PG+ G +G  G
Sbjct: 256  DLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG 315

Query: 1180 PSGLPGPKGEKGYPGE-----------------------DSTVLGPPGPRGEPGPVGDQG 1216
              G PG  GE G  G+                       D    GPPGPRG  GP G  G
Sbjct: 316  NRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSG 375

Query: 1217 ERGEPGAEG-----YKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGA 1271
              G PG+ G      +G  G PGL+G+ G++G PG+    G  G  G  GS G  G  G 
Sbjct: 376  PPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDA-MGTPGSPGCAGSPGLPGSPGP 434

Query: 1272 PGPSG----KPGIPGLQGLLGPKGIQGYHGADGISGNPGKI--------GPPGKQGLPG- 1318
            PGP G    + G PG  GL G  G  G  G DG  G PG +        GPPG  GLPG 
Sbjct: 435  PGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGL 494

Query: 1319 --IRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHR-GAQG 1375
              ++G PGR G AG  G PG  G++GLPG PG  G +G+      PG++G++G     +G
Sbjct: 495  HGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGD------PGLKGEKGETLQPEG 548

Query: 1376 DQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLG 1435
              G  GDPGL+GQPG  G+ G+ G  G  G  GP+G+  + G  G +GP G  G+ G  G
Sbjct: 549  QVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPG 608

Query: 1436 REGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQMDINAAI 1488
              G  GP G  GP+GE G       QG +G PG PGPPG  GPR ++ ++  +
Sbjct: 609  PAGPAGPPGY-GPQGEPGL------QGTQGVPGAPGPPGEAGPRGELSVSTPV 654



 Score =  335 bits (860), Expect = 2e-91
 Identities = 205/477 (42%), Positives = 235/477 (49%), Gaps = 53/477 (11%)

Query: 484  MEYLRGPKGDTGPPGPPGP------------------------AGIPGPSGKRGPRGIPG 519
            M  L+G KG  GP GPPGP                         G+PG  GKRG  G PG
Sbjct: 977  MPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036

Query: 520  PHGNPGLPGLPGPKGPKGDPGFS----PGQP----VPGEKGDQGLSGLMGPPGMQGDKGL 571
              G PGLPG+ G +G KG+PG+S    PG P     PG  GD G  G MG PG  G  G 
Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGP 1096

Query: 572  KGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGP 631
             G  G PG PG  G+PG  G  G  G+ G +GL GP G  GP G  GF GSPG  G  G 
Sbjct: 1097 AGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGD 1156

Query: 632  EGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGP 691
            +G  GIPG  G+KG  G    P   G RG  G  G+ G  G  G PG PG +G++G  GP
Sbjct: 1157 QGRDGIPGPAGEKGETGLLRAPP--GPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP 1214

Query: 692  IGPAGI---PGPMGL--------SGNKGLPGIKGDKGEQGTAGELGEP--GYPGDKGAVG 738
             GP GI   PGP GL        +GN+G PG +G  G  G  G  G    G  GDKG++G
Sbjct: 1215 RGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMG 1274

Query: 739  LPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPG 798
             PGP G  G +G  G  G  G  G  G PGP G PG  G PG  G +G  G LG+ GPPG
Sbjct: 1275 HPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPG 1334

Query: 799  PPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVG 858
            P G KG  G  G  G    +   G PG  G  GEPG +G  G  G  GN+G  G  G  G
Sbjct: 1335 PIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPG 1394

Query: 859  LPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARG 915
              G+ G  G  GEKG +GS G  GP G  G+      PG+ G  G  G P     RG
Sbjct: 1395 KDGKPGTPGPAGEKGNKGSKGEPGPAGSDGL------PGLKGKRGDSGSPATWTTRG 1445



 Score =  240 bits (613), Expect = 8e-63
 Identities = 143/336 (42%), Positives = 170/336 (50%), Gaps = 16/336 (4%)

Query: 475  YEDLNTMLEMEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPG-LPGPK 533
            ++ +  +L    +RGP G  G PG PGP GI G  G+    GIPGP G  G  G L  P 
Sbjct: 1123 FKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGR---DGIPGPAGEKGETGLLRAPP 1179

Query: 534  GPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPG--FAG 591
            GP+G+PG    Q   G++G  G  GL G  G  GD G +G  G+ G PG  G+PG    G
Sbjct: 1180 GPRGNPG---AQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPG 1236

Query: 592  NIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQG 651
              G+ G PG +G  G  G PGP G+   IG  G+ G +G  G +G PG  G  G  GR G
Sbjct: 1237 QTGNRGPPGSRGSPGAPGPPGPPGSH-VIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLG 1295

Query: 652  FPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPG 711
             PG  G  GP G  G  G  G  G  G PG  GS+GP GPIGP G PG  G  G   +  
Sbjct: 1296 APGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIIS 1355

Query: 712  IKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEG 771
            + G  G  GT      PG PG +G  G PGPPG  G  GP G+ G  G  G  GP G +G
Sbjct: 1356 LPGSPGPPGT------PGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409

Query: 772  FPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQG 807
              G  G PG  G +G  GL G RG  G P    T+G
Sbjct: 1410 NKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
            sapiens]
          Length = 1670

 Score =  767 bits (1981), Expect = 0.0
 Identities = 499/1206 (41%), Positives = 582/1206 (48%), Gaps = 239/1206 (19%)

Query: 491  KGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGE 550
            KGD G PG PGP G+PGP G  GP G PGP G  G PG  GP+GPKG  G    + V G 
Sbjct: 170  KGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMG----ERVIGH 225

Query: 551  KGDQGLSGLMGPPG-----------------MQGDKGLKGHPGLPGLPGEQGIPG--FAG 591
            KG++G+ GL GPPG                 ++G+KG KG  G PG PG  G+PG  +  
Sbjct: 226  KGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGS 285

Query: 592  NIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQG 651
              G+PG PG QG  G +G PG  G++G             +G RG PG+ G+ G KG++G
Sbjct: 286  EKGAPGDPGLQGKPGKDGVPGFPGSEGV------------KGNRGFPGLMGEDGIKGQKG 333

Query: 652  FPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMG-----LSGN 706
              G  G RGP     +    G  G PG PG RG+ GP GP GP G+PG  G     L G 
Sbjct: 334  DIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGA 393

Query: 707  KGLPGIKGDKGEQGTAGE--LGEPGYPGDKGAVGLPG----------------PPGMRGK 748
             G PG+KG KGE+G  G+  +G PG PG  G+ GLPG                PPG  G 
Sbjct: 394  PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGL 453

Query: 749  SGPSGQTGDPGLQGPSG--------------PPGPEGFPGDIGIPGQNGPEGPKGLLGNR 794
             G  G  G PG+ GP G              PPG  G PG  G+ G  G +G  GL G+ 
Sbjct: 454  PGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSP 513

Query: 795  GPPG---------------PPGLKGTQGE----EGPIGAFGELGPRGKPGQKGYAGEPGP 835
            G PG                PGLKG +GE    EG +G  G+ G RG+PG+KG  G PG 
Sbjct: 514  GSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGT 573

Query: 836  EGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGE------KGV 889
             G+KG  G +G +   GE G  G PG+ G  GS G  G  G PG  GPQGE      +GV
Sbjct: 574  PGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGTQGV 632

Query: 890  MGYPGPPG-------------VPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRG------ 930
             G PGPPG             VPGP GP G PGH G +GPPG  G  G+ G  G      
Sbjct: 633  PGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDG 692

Query: 931  -----------PDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPG------------- 966
                       P G  G+QG  G KG  G  GK G  GL GK G PG             
Sbjct: 693  EPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP 752

Query: 967  -------ERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGT--EG 1017
                   ERG  G+ G  GLPG  G  G PG  GL G +GD G PG  G +GPPG   EG
Sbjct: 753  GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812

Query: 1018 ESGLQGEPGA---KGDVGTAGSVGGTGEPGL-----------RGEPGAPGEEGLQGKDGL 1063
              G QG PG    KG  G  G  G  G+PG+            G PG PG +G  G  G 
Sbjct: 813  PRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ 872

Query: 1064 KGVPGGRGL---PGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPG---QRGRPGK 1117
            +G PG  G+   PGEDG  G MG PG IGP G  G  G PG  G  GIPG   QRG PG 
Sbjct: 873  RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932

Query: 1118 KG---DKGQIGPT---------------------GEVGSRGPPGKIGKSGPKGARGTRGA 1153
            KG   DKG  GP+                     GE G+RG PG  G  G KG  G  G 
Sbjct: 933  KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992

Query: 1154 VGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKG---YPGE--------------- 1195
             G  G +G  G PG PG RG  G  G  G+PG KG++G   +PG                
Sbjct: 993  PGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGD 1052

Query: 1196 -------DSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEP 1248
                   + T  GPPGP G+PG  GD G++GE G  G  GH+G  G  GA G  G PG P
Sbjct: 1053 KGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLP 1112

Query: 1249 GDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKI 1308
            G  G  G   + G +G KG  G PG  G PG+PG  G  GP GI+G  G DGI G  G+ 
Sbjct: 1113 GKPGPHG---DLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEK 1169

Query: 1309 G-------PPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQ 1361
            G       PPG +G PG +G  G  G   APG PG+ G  G  G  G +GP G +G PG 
Sbjct: 1170 GETGLLRAPPGPRGNPGAQGAKGDRG---APGFPGLPGRKGAMGDAGPRGPTGIEGFPGP 1226

Query: 1362 PG-----IQGKRGHRGAQGDQGPCGDPGLKGQPGEY--GVQGLTGFQGFPGPKGPEGDAG 1414
            PG     I G+ G+RG  G +G  G PG  G PG +  G++G  G  G PGPKGP G AG
Sbjct: 1227 PGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286

Query: 1415 IVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPG 1474
             +G  G  G  G  G  GP G  G  G  G  G +G  GF G  GP GP G  GPPG  G
Sbjct: 1287 DMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRG 1346

Query: 1475 APGPRK 1480
             PG  K
Sbjct: 1347 DPGTLK 1352



 Score =  754 bits (1947), Expect = 0.0
 Identities = 490/1176 (41%), Positives = 578/1176 (49%), Gaps = 189/1176 (16%)

Query: 488  RGPKGDTGPPGPPGPAGIPGPS--------------GKRGPRGIPG------PHGNPGLP 527
            +G KG  G PGPPGP+G+PG S              GK G  G+PG        GN G P
Sbjct: 261  KGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFP 320

Query: 528  GLPGP---KGPKGD---PGF-----------------SPGQPVP-GEKGDQGLSGLMGPP 563
            GL G    KG KGD   PGF                 +PG P P G +G QG SG  G P
Sbjct: 321  GLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVP 380

Query: 564  GMQGDK--GLKGHPGLPGLPGEQG-----------IPGFAGNIGSPGYPGRQGLAGPEGN 610
            G  G    GL+G PG PGL G +G            PG  G  GSPG PG  G  GP G+
Sbjct: 381  GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGD 440

Query: 611  -------PGPKGAQGFIGSPGEAGQLGPEGERG--------IPGIRGKKGFKGRQGFPGD 655
                   PG  G  G++GSPG  G  GP+GE G        IPG  G  G  G  G  G 
Sbjct: 441  IVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGI 500

Query: 656  FGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVG-------------PVGPIGPAGIPGPMG 702
             G +G AGL GSPG  G TG PGFPG  G+ G             P G +G  G PG  G
Sbjct: 501  PGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRG 560

Query: 703  LSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQG 762
              G KGL GI G  G +G  G  GE    G+KG  G PG PG  G  GP+G  G PG  G
Sbjct: 561  QPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY-G 619

Query: 763  PSGPPGPEGFPGDIGIPGQNGPEGPKGLL-------GNRGPPGPPGLKGTQGEEGPIGAF 815
            P G PG +G  G  G PG  G  GP+G L       G  GPPGPPG  G QG  G  G+ 
Sbjct: 620  PQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSL 679

Query: 816  GELGPRGKPGQKG--------YAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTG 867
            G+ G  G PG  G        + G PGP+G +G  G +G++G  G+ G  GLPG+ G+ G
Sbjct: 680  GKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPG 739

Query: 868  SIGEK--------GERGSPGPLGPQGEKGVMGYPGPPGVPG---------PIGPLGLPGH 910
            + GE         G  G PG  G  GE G +G PG PG+PG         P G  G PG 
Sbjct: 740  AKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGP 799

Query: 911  VGARGPPGS--QGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRG--PHGLIGKTGNPG 966
             G +GPPG   +GP+G +G  G +GL G+QG +G  G KGD G  G    G  G+TG+PG
Sbjct: 800  PGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPG 859

Query: 967  ------------ERGFQGKPGL------------QGLPGSTGDRGLPGEPGLRGLQGDVG 1002
                        +RG+ G PG+             G PG+ G  G PG PG  G +G  G
Sbjct: 860  IPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPG 919

Query: 1003 PPGEMGMEGPPGTEGESGLQGEPGA---------KGDVGTAGSVGGTGEPGLRGEPGAPG 1053
             PG  G  G PG +GE G +G PG          KG+ G  G  G  GE G RG PG PG
Sbjct: 920  IPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPG 979

Query: 1054 EEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRG 1113
             +GL+G  G  G PG RG  G  G  GE GL GI G +G  G  G  G  G +G PG+ G
Sbjct: 980  LKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAG 1039

Query: 1114 RPGK------KGDKGQIGPT-----GEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGP 1162
            RPG       +GDKG+ G +     G  G  G PG  G  G KG  G  G  GHLG  GP
Sbjct: 1040 RPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGP 1099

Query: 1163 DGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRG---EPGPVG---DQG 1216
            +G PG PG  G  G+PGP G  G KG KG  G    + GPPG  G    PGP+G   DQG
Sbjct: 1100 EGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPG-IRGPPGLPGFPGSPGPMGIRGDQG 1158

Query: 1217 ERGEPGAEGYKGHVGV----PGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAP 1272
              G PG  G KG  G+    PG RG  G QG  G+ G  G  GL G +G+ G+ G +G  
Sbjct: 1159 RDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPT 1218

Query: 1273 GPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQG--LPGIRGGPGRTGLAG 1330
            G  G PG PGL G + P G  G  G  G  G+PG  GPPG  G  + GI+G  G  G  G
Sbjct: 1219 GIEGFPGPPGLPGAIIP-GQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPG 1277

Query: 1331 APGPPGVKGSSG------LPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPG 1384
              GPPG  G  G       PG+PG+ GP+G+ G  G PG++G++G+ G  G  GP G  G
Sbjct: 1278 PKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIG 1337

Query: 1385 LKGQPGEYGVQG---LTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIG 1441
             KG PG  G  G   +    G PGP G  G+ G+ G  GP GP G+ G  GP G+ G  G
Sbjct: 1338 PKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDG 1397

Query: 1442 PTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPG 1477
              G  GP GEKG +G  G  GP G  G PG  G  G
Sbjct: 1398 KPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433



 Score =  754 bits (1946), Expect = 0.0
 Identities = 509/1309 (38%), Positives = 597/1309 (45%), Gaps = 329/1309 (25%)

Query: 489  GPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGD------PGFS 542
            G KG+ G  G PGP G PG  G  GP G+PGP G  G PGLPG  G KG       PGFS
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 543  PGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFA------------ 590
                +PG  G+ G  GL+G PG  G KG +G PGLPG  G  GIPG A            
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 591  --------GNIGSPGYPGRQGLAGPEGNP---GPKGAQGFIGSPGEAGQLGP-------- 631
                    G+ G PG PG QGL GP G P   GP G  GF G PG  G  GP        
Sbjct: 163  EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERV 222

Query: 632  ---EGERGIPGIRGKKG-----------------FKGRQGFPGDFGDRGPAGLDGSPGLV 671
               +GERG+ G+ G  G                  KG +G  G  G+ GP G  G PG  
Sbjct: 223  IGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGES 282

Query: 672  GGT--GPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPG 729
             G+  G PG PGL+G     G  G  G PG  G+ GN+G PG+ G+ G +G  G++G PG
Sbjct: 283  YGSEKGAPGDPGLQGK---PGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPG 339

Query: 730  YPG---------DKGAVGLPGPPGMRGKSGPSGQTGDPGLQGP----------------- 763
            + G         +KG  G PGPPG RG  GP G +G PG+ G                  
Sbjct: 340  FRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGL 399

Query: 764  -----------------------------SGPPGPEGFPGDI------------------ 776
                                          G PGP G PGDI                  
Sbjct: 400  KGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGS 459

Query: 777  -GIPGQNGPEGPKGLLGNR-----GPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYA 830
             GIPG +GP+G  GLL  +     GPPG PGL G  G +G  G  G  G +G PG  G  
Sbjct: 460  PGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNT 519

Query: 831  GEPGPEGLKGEVGDQGNIGKIGET----GPVGLPGEVGMTGSIGEK-------------- 872
            G PG  G  G  GD G  G+ GET    G VG+PG+ G+ G  G K              
Sbjct: 520  GLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGL 579

Query: 873  ----------------------GERGSPGPLGP--------------QGEKGVMGYPGPP 896
                                  G  GSPGP GP              QG +GV G PGPP
Sbjct: 580  PGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPP 639

Query: 897  G-------------VPGPIGPLGLPGHVGARGP---PGSQGPKGQRGSRGPDGLLGEQGI 940
            G             VPGP GP G PGH G +GP   PGS G  G  G  GPDG  G  GI
Sbjct: 640  GEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI 699

Query: 941  --QGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQG--------LPGSTGDRGLPG 990
               G  G KGDQG  G  G +G  G  GE G  GKPGL G        +PG  G  G PG
Sbjct: 700  GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 991  EPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSV--------GGTGE 1042
            E G  G  G++G PG  G+ G PG EG  G +G+PG  G  G  G          G  G 
Sbjct: 760  ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819

Query: 1043 PGL---------------RGEPGAPG--EEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLP 1085
            PGL               +G+PG PG    G  G+ G  G+PG +G  G  G++G  G P
Sbjct: 820  PGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNP 879

Query: 1086 GIIGPLGRSGQTGL---------PGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPP 1136
            GI+GP G  G  G+         PGP G  G PGQRG PG  G KGQ G  G  G +G  
Sbjct: 880  GILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDK 939

Query: 1137 GKIGKS------GPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEK 1190
            G  G S      G KG  G +G  G+ G  G  G PG+PG +G +G PGP+G PGP+G+ 
Sbjct: 940  GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999

Query: 1191 GYPGEDSTVLGPPGPRGEPGPVGDQ---GERGEPGAEGYKGHVGVPGLRGATGQQGP--- 1244
            G  G      G PG RG PG +G+    G +G+ G  G+ G  G PGL G  G QG    
Sbjct: 1000 GSTGNP----GEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE 1055

Query: 1245 --------PGEPGDQGEQGLKGERGSEGNKGKKGAP---------GPSGKPGIPGLQGLL 1287
                    PG PG  G+ GL G+ G +G  G+ G P         G  G PG PGL G  
Sbjct: 1056 PGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKP 1115

Query: 1288 GPKGIQGYHGADGISGNPGKIGPPGKQGLP------GIRGGPGRTGLAGAPGPPGVKGSS 1341
            GP G  G+ G  G+ G PG  GPPG  G P      GIRG  GR G+   PGP G KG +
Sbjct: 1116 GPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGI---PGPAGEKGET 1172

Query: 1342 GL-------PGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPC------GDPGL--- 1385
            GL        G+PG QG KG++G PG PG+ G++G  G  G +GP       G PGL   
Sbjct: 1173 GLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGA 1232

Query: 1386 --KGQPGEYGVQGLTGFQGFPGPKGP--------EGDAGIVGISGPKGPIGHRGNTGPLG 1435
               GQ G  G  G  G  G PGP GP        +GD G +G  GPKGP G  G+ GP G
Sbjct: 1233 IIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPG 1292

Query: 1436 REGIIGPTGRTGPRGEKGFRGETGPQGPRGQP------GPPGPPGAPGP 1478
            R G  G  G  GPRG+ GF+G  G +G +G P      GPPGP G  GP
Sbjct: 1293 RLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGP 1341



 Score =  748 bits (1931), Expect = 0.0
 Identities = 484/1192 (40%), Positives = 581/1192 (48%), Gaps = 205/1192 (17%)

Query: 485  EYLRGPKGDTGPPGPPGPAGIPGP-----SGKRGPRGIPGPHGNPGLPGLPGPKGPKGDP 539
            E + G KG+ G  G  GP G PG      +G      + G  G+ G  G PGP GP G P
Sbjct: 220  ERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLP 279

Query: 540  GFSPG--QPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPG 597
            G S G  +  PG+ G QG  G  G PG  G +G+KG+ G PGL GE GI G  G+IG PG
Sbjct: 280  GESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPG 339

Query: 598  Y------------PGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPE--GERGIPGIRGK 643
            +             G +G  GP G  G +G QG  G PG  G  G    G RG PG  G 
Sbjct: 340  FRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGL 399

Query: 644  KGFKGRQGFPGD--FGDRGPAGLDGSPGLVGGTGPP----------------GFPGLRGS 685
            KG KG +G PG    G  G  G  GSPGL G  GPP                G PG  GS
Sbjct: 400  KGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGS 459

Query: 686  VGPVGPIGPAG-----------IPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDK 734
             G  G  GP G           IPGP GL G  GL G+KG  G QG AG  G PG PG+ 
Sbjct: 460  PGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNT 519

Query: 735  GAVGLPGPPGMRGKSG----------PSGQT---GDPGLQGPSGPPGPEGFPGDIGIPGQ 781
            G  G PG PG +G  G          P GQ    GDPGL+G  G  G +G PG  G+ G 
Sbjct: 520  GLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGL 579

Query: 782  NGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGE--LGPRGKPGQKGYAGEPGPEGLK 839
             GP+G   L G +G  GPPG  G+ G  GP G  G    GP+G+PG +G  G PG  G  
Sbjct: 580  PGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPP 639

Query: 840  GEVGDQGNI-------GKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGV--M 890
            GE G +G +       G  G  GP G PG  G  G  G  G+ G PG  GP GE G+  +
Sbjct: 640  GEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI 699

Query: 891  GYPGPP------GVPGPIGPLGLPGHVG--------------------ARGPPGSQGPKG 924
            G+PGPP      G PG  G LG PG +G                      G PG+ G  G
Sbjct: 700  GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 925  QRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGE-----------RGFQGK 973
            +RG+ G  G +G  G+ G  G  G++G  GP G  G+ G PGE           RG QG 
Sbjct: 760  ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819

Query: 974  PGLQGLPGSTGDR-----------------GLPGE---PGLRGLQGDVGP------PGEM 1007
            PGL GL G  G R                 G PGE   PG+ G QG++GP      PG  
Sbjct: 820  PGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNP 879

Query: 1008 GMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVP 1067
            G+ GPPG +G  G+ G PGA   +G  G  G  G PG RG PG PG +G +G  G KG  
Sbjct: 880  GILGPPGEDGVIGMMGFPGA---IGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQ 936

Query: 1068 GGRGLPGED------GEKGEMGLPGIIGPLGRSGQ---TGLPGPEGIVGIPGQRGRPGKK 1118
            G +G PG        G+KGE GL G  G  G  G     G+PG +G+ G+PG  G PG +
Sbjct: 937  GDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPR 996

Query: 1119 GDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQP 1178
            GD G  G  GE G RG PG +G  G  G++G RG +G  G  G  G PGI G +G +G+P
Sbjct: 997  GDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056

Query: 1179 GPS-----GLPGPKGEKGYPGEDSTV-----------LGPPGPRGEPGPVGDQGERGEPG 1222
            G S     G PGP G+ G PG+               LGP GP G PG  G  G  G+PG
Sbjct: 1057 GYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPG 1116

Query: 1223 AEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPG 1282
              G  G  G+ GL G  G +GPPG PG  G  G  G R   G++G+ G PGP+G+ G  G
Sbjct: 1117 PHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIR---GDQGRDGIPGPAGEKGETG 1173

Query: 1283 -LQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSS 1341
             L+   GP+G  G  GA G  G PG  G PG++G  G  G  G TG+ G PGPPG+ G+ 
Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233

Query: 1342 GLPGSPGIQGPKGEQGLPGQPG--------IQGKRGHRGAQGDQGPCGDPGLKGQ----- 1388
             +PG  G +GP G +G PG PG        + G +G +G+ G  GP G PG  G      
Sbjct: 1234 -IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPG 1292

Query: 1389 -------PGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGII- 1440
                   PG  G +G  GFQGFPG KG +G+ G +G  GP GPIG +G  G  G  G + 
Sbjct: 1293 RLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLK 1352

Query: 1441 -----GPTGRTGPRGEKGFRGETGPQ---------GPRGQPGPPGPPGAPGP 1478
                 G  G  G  GE G +GE GP          GPRG+PG  G PG PGP
Sbjct: 1353 IISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGP 1404



 Score =  733 bits (1891), Expect = 0.0
 Identities = 475/1108 (42%), Positives = 550/1108 (49%), Gaps = 171/1108 (15%)

Query: 491  KGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGN--------PGLPGLPGPKGPKGDPGF- 541
            KGD G PGPPGP G  GP G  GP G+PG  G+        PG PGL G KG +G PG  
Sbjct: 353  KGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKD 412

Query: 542  ------------------SPGQPVP--------GEKGDQGLSGLMGPPGMQGDKGLKGHP 575
                              SPG P P        G  GD GL G +G PG+ G  G KG P
Sbjct: 413  AMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEP 472

Query: 576  GL-----PGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLG 630
            GL     P +PG  G+PG  G  G  G PGRQG AG +G+PG  G  G  G PG  G  G
Sbjct: 473  GLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQG 532

Query: 631  -------------PEGERGIPG---IRGKKGFKGRQGFPGDFGDRGPAGLDGS---PGLV 671
                         PEG+ G+PG   +RG+ G KG  G PG  G +G  G  G     G  
Sbjct: 533  DPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEK 592

Query: 672  GGTGPPGFPGLRGSVGPVGPIGPAGI--PGPMGLSGNKGLPGIKGDKGEQGTAGELGE-- 727
            G  GPPG PG  GS GP GP GP G    G  GL G +G+PG  G  GE G  GEL    
Sbjct: 593  GDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652

Query: 728  --PGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPG--------PEGFPGDIG 777
              PG PG  G  G PGP G  G  G  G+ GDPGL GP G PG        P G  GD G
Sbjct: 653  PVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQG 712

Query: 778  IPGQNGPEGPKGLLGNRGPPGPPGLKGTQGE-----------------EGPIGAFGELG- 819
             PG  G  G  G +G  G PG PGL G +GE                  G  G  GE+G 
Sbjct: 713  FPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGL 772

Query: 820  -----------------PRGKPGQKGYAGEPGP-----------EGLKGEVGDQGNIGKI 851
                             PRG PGQ G  GE GP           +GL G  G +G  G+ 
Sbjct: 773  PGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRR 832

Query: 852  GETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMG---YPGPPGVPGP------I 902
            G+TGP G PG  G+  S G  GE GSPG  G QGE G +G   YPG PG+ GP      I
Sbjct: 833  GKTGPKGDPGIPGLDRS-GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVI 891

Query: 903  GPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGL---I 959
            G +G PG +G  GPPG+ G  GQRGS G  G+ G++G  GAKGE+GD+G  GP  +   I
Sbjct: 892  GMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVI 951

Query: 960  GKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGES 1019
            G  G PG +GF G PG +   G+ G  G+PG  GL+GL G  GPPG  G  G  G  GE 
Sbjct: 952  GDKGEPGLKGFAGNPGEK---GNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEP 1008

Query: 1020 GLQGEPGAKGDVGTAGSVG--GT-GEPGLRGEPGAPGEEGLQG-----------KDGLKG 1065
            GL+G PG+ G++G  GS G  GT G PG  G PG PG  GLQG           + G  G
Sbjct: 1009 GLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG 1068

Query: 1066 VPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIG 1125
              G  GLPG+ G+KGEMG PG  G LG +G  G PG  G  G+PG+ G  G  G KG  G
Sbjct: 1069 PTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKG 1128

Query: 1126 PTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPG 1185
              G  G RGPPG  G  G  G  G RG  G  G+ GP GE G  G    +  PGP G PG
Sbjct: 1129 LLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLL--RAPPGPRGNPG 1186

Query: 1186 PKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPG--LRGATGQQG 1243
             +G KG    D    G PG  G  G +GD G RG  G EG+ G  G+PG  + G TG +G
Sbjct: 1187 AQGAKG----DRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRG 1242

Query: 1244 PPGEPGDQGEQGLKGERGSE--GNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGI 1301
            PPG  G  G  G  G  GS   G KG KG+ G  G  G PG  G +GP    G  GA G 
Sbjct: 1243 PPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP---PGRLGAPGT 1299

Query: 1302 SGNPGKIGPPGKQGLPGI---RGGPGRTGLAGAPGPPGVKGSSGLPGSPG------IQGP 1352
             G PG  G PG QG PG+   +G PG  G  G PGP G KG  G+ G PG      + G 
Sbjct: 1300 PGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGS 1359

Query: 1353 KGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGD 1412
             G  G PG+PG+QG+ G  G  G+ GPCG  G  G+ G+ G  G  G +G  G KG  G 
Sbjct: 1360 PGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGP 1419

Query: 1413 AGIVGISGPKGPIGHRGNTGPLGREGII 1440
            AG  G+ G KG  G  G+       G +
Sbjct: 1420 AGSDGLPGLKGKRGDSGSPATWTTRGFV 1447



 Score =  684 bits (1764), Expect = 0.0
 Identities = 438/1047 (41%), Positives = 525/1047 (50%), Gaps = 163/1047 (15%)

Query: 568  DKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAG 627
            DKG     G  G  GE+G PG       PG PG++G  GPEG PGP+G +GF G PG  G
Sbjct: 35   DKGQCFCDGAKGEKGEKGFPG------PPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTG 88

Query: 628  QLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVG 687
                   +G+ GI G  GF G  G PG  G+ GP GL G PG  G  G  GFPGL G+  
Sbjct: 89   S------KGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGT-- 140

Query: 688  PVGPIGPAGIPGPMGLSGNKGLPG--------IKGDKGEQGTAGELGEPGYPGDKGAVGL 739
                +G  GIPG  GL G KG P          KGD G  G  G  G PG PG  G VG 
Sbjct: 141  ----LGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP 196

Query: 740  PGPPGM------RGKSGPSGQTGDP--------GLQGPSGPPGPEG-----FPGDIGIPG 780
            PGPPG        G  GP G  G+         G++G +GPPGP G       G      
Sbjct: 197  PGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTD 256

Query: 781  QNGPEGPKGLLGNRGPPGPPGLKG-TQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLK 839
              G +G KG +G  GPPGP GL G + G E   GA G+ G +GKPG+ G  G PG EG+K
Sbjct: 257  LKGEKGDKGAMGEPGPPGPSGLPGESYGSEK--GAPGDPGLQGKPGKDGVPGFPGSEGVK 314

Query: 840  GE------VGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYP 893
            G       +G+ G  G+ G+ GP G  G      +  EKG+ G+PGP GP+G +G  G  
Sbjct: 315  GNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPS 374

Query: 894  GPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPD--------GLLGEQGIQGAKG 945
            GPPGVPG  G    PG  GA G PG +G KG+RG  G D        G  G  G+ G+ G
Sbjct: 375  GPPGVPGSPGS-SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPG 433

Query: 946  EKGDQG----KRGP---HGLIGKTGNPGERGFQGK-----------------PGLQGLPG 981
              G  G    ++GP   HGL G  G+PG  G  G                  PGL GLPG
Sbjct: 434  PPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493

Query: 982  STGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTA----GSV 1037
              G +G+PG  G  GL+G  G PG  G+   PG  G  G QG+PG KG+ G      G V
Sbjct: 494  LHGVKGIPGRQGAAGLKGSPGSPGNTGL---PGFPGFPGAQGDPGLKGEKGETLQPEGQV 550

Query: 1038 GGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRG---LPGEDGEKGEMGLPGIIGPLGRS 1094
            G  G+PGLRG+PG  G +G+ G  G+KG+PG +G   L GE G++G  G PG  G  G +
Sbjct: 551  GVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPA 610

Query: 1095 GQTGLPG--PEGIVGIPGQRGRPGKKGDKGQIGPTGEV----------GSRGPPGKIGKS 1142
            G  G PG  P+G  G+ G +G PG  G  G+ GP GE+          G  GPPG  G  
Sbjct: 611  GPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQ 670

Query: 1143 GPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSG------------LPGPKGEK 1190
            GP G  G+ G  G  GL GPDGEPGIPG  G  G PGP G             PG  GE 
Sbjct: 671  GPPGIPGSLGKCGDPGLPGPDGEPGIPGI-GFPGPPGPKGDQGFPGTKGSLGCPGKMGEP 729

Query: 1191 GYPGEDS----------TVLGPPGPRGEPGPVGDQGERGE------PGAEGYKGHVGVPG 1234
            G PG+             + G PG  G PG  G+ GE GE      PG  G  G+ G+ G
Sbjct: 730  GLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDG 789

Query: 1235 LRGATGQQGPPGEPGD--------QGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQ-- 1284
             RG  GQ GPPGE G         +G QGL G  G +G +G++G  GP G PGIPGL   
Sbjct: 790  PRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRS 849

Query: 1285 ---------GLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPP 1335
                     G+ G +G  G  G  G  GNPG +GPPG+ G+ G+ G P   G  G PGPP
Sbjct: 850  GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFP---GAIGPPGPP 906

Query: 1336 GVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQ---GPCGDPGLKGQPGEY 1392
            G  G+ G  GSPGI G KG++G PG  G QG +G+ G        G  G+PGLKG  G  
Sbjct: 907  GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP 966

Query: 1393 GVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEK 1452
            G +G  G  G PG KG +G  G  G  GP+G +G  GN G  G  GI G  G  G  G K
Sbjct: 967  GEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026

Query: 1453 GFRGETGPQGPRGQPGPPGPPGAPGPR 1479
            G RG  G  G  G+PG PG  G  G +
Sbjct: 1027 GKRGTLGFPGRAGRPGLPGIHGLQGDK 1053



 Score =  672 bits (1733), Expect = 0.0
 Identities = 425/1000 (42%), Positives = 500/1000 (50%), Gaps = 155/1000 (15%)

Query: 486  YLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQ 545
            Y+ GP G  G PG  G  GIPG  G  G +G PG  GN GLPG PG  G +GDPG     
Sbjct: 481  YIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPG----- 535

Query: 546  PVPGEKGD----QGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNI-------- 593
             + GEKG+    +G  G+ G PG++G  G KG  G+PG PG +G+PG  G +        
Sbjct: 536  -LKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGD 594

Query: 594  -------GSPGYPGRQGLA-----GPEGNPGPKGAQGFIGSPGEAGQLGPEGE------- 634
                   GSPG PG  G A     GP+G PG +G QG  G+PG  G+ GP GE       
Sbjct: 595  QGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPV 654

Query: 635  ---RGIPGIRGKKGFKGRQGFPGDFGDRGPAGL---DGSPGL--VGGTGPP------GFP 680
                G PG  G  G +G  G PG  G  G  GL   DG PG+  +G  GPP      GFP
Sbjct: 655  PGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFP 714

Query: 681  GLRGSVGPVGPIGPAGIPGPMGLSGNKGL--------PGIKGDKGEQGTAGELGEPGYPG 732
            G +GS+G  G +G  G+PG  GL G KG         PG  G  GE+G +GE GE G P 
Sbjct: 715  GTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLP- 773

Query: 733  DKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGP--EGFPGDIGIPGQNGPEGPKGL 790
              G  GLPG PG  G  GP G  G PG  G  GPPG   EG  G  G+PG NG +G +G 
Sbjct: 774  --GLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGR 831

Query: 791  LGNRGPPGPPGLKGTQ-----GEEGPIGAFGELGPRGKPGQKGYAGEP---GPEGLKGEV 842
             G  GP G PG+ G       GE G  G  G  G  G  GQ+GY G P   GP G  G +
Sbjct: 832  RGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVI 891

Query: 843  GDQGNIGKIGETGPVGLPGEVGMTGS---------------IGEKGERGSPGP------L 881
            G  G  G IG  GP G PG  G  GS                GE+G++G+PGP      +
Sbjct: 892  GMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVI 951

Query: 882  GPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQ 941
            G +GE G+ G+ G PG  G  G  G+PG  G +G PG  GP G RG  G  G  GE G++
Sbjct: 952  GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011

Query: 942  GAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGL-----------------PGSTG 984
            G  G  G+ G  G  G  G  G PG  G  G PG+ GL                 PG TG
Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071

Query: 985  DRGLPGEPGLRGLQGDVGPPGEMGMEGP---PGTEGESGLQGEPGAKGDVGTAGSVGGTG 1041
            D GLPG+ G +G  G  GPPG +G  GP   PG+ G  GL G+PG  GD+G  G  G  G
Sbjct: 1072 DPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLG 1131

Query: 1042 EPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMG-LPGIIGPLGRSGQTGLP 1100
             PG+RG PG PG  G  G  G++G  G  G+PG  GEKGE G L    GP G  G  G  
Sbjct: 1132 PPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAK 1191

Query: 1101 GPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGK--SGPKGARGTRGAVGHLG 1158
            G  G  G PG  GR G  GD G  GPTG  G  GPPG  G    G  G RG  G+ G  G
Sbjct: 1192 GDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPG 1251

Query: 1159 LMGPDGEP-----GIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVG 1213
              GP G P     GI G +G  G PGP G PG  G+ G PG     LG PG  G PGP G
Sbjct: 1252 APGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR----LGAPGTPGLPGPRG 1307

Query: 1214 DQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPG 1273
            D G +G PG +G KG+   PG  G+    GPPG  G +G  G++G+ G+       G+PG
Sbjct: 1308 DPGFQGFPGVKGEKGN---PGFLGSI---GPPGPIGPKGPPGVRGDPGTLKIISLPGSPG 1361

Query: 1274 PSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPG 1333
            P G PG PG+QG  GP G                  PPG  G  G RG PG+ G  G PG
Sbjct: 1362 PPGTPGEPGMQGEPGPPG------------------PPGNLGPCGPRGKPGKDGKPGTPG 1403

Query: 1334 PPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGA 1373
            P G KG+ G  G P   GP G  GL   PG++GKRG  G+
Sbjct: 1404 PAGEKGNKGSKGEP---GPAGSDGL---PGLKGKRGDSGS 1437



 Score =  609 bits (1570), Expect = e-174
 Identities = 364/831 (43%), Positives = 428/831 (51%), Gaps = 92/831 (11%)

Query: 489  GPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGL--PGPKGPKGDPGFSPGQP 546
            GP G  G PGP GP GIPG  GK G  G+PGP G PG+PG+  PGP GPKGD GF     
Sbjct: 659  GPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGF----- 713

Query: 547  VPGEKGDQGLSGLMGPPGMQGDKGLKGH-----------PGLPGLPGEQGIPGFAGNIGS 595
             PG KG  G  G MG PG+ G  GL G            PG PG PGE+G  G  G IG 
Sbjct: 714  -PGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGL 772

Query: 596  PGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLG-----PEGERGIPGIRGKKGFKGRQ 650
            PG PG  G  G EG  GP+G  G  G PGE G  G     P G +G+PG+ G KG +GR+
Sbjct: 773  PGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRR 832

Query: 651  GFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLP 710
            G  G  GD G  GLD S G  G TG PG PG +G +GP+G  G  G PG +G  G  G+ 
Sbjct: 833  GKTGPKGDPGIPGLDRS-GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVI 891

Query: 711  GIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPS------ 764
            G+ G  G  G  G  G PG PG +G+ G+PG  G RG  G  G+ GD G  GPS      
Sbjct: 892  GMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVI 951

Query: 765  ---GPPGPEGFPGDIG------------------IPGQNGPEGPKGLLGNRGPPGPPGLK 803
               G PG +GF G+ G                  +PG  GP GP+G LG+ G PG PGL+
Sbjct: 952  GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011

Query: 804  GTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKI--------GETG 855
            G  G  G +G  G  G RG  G  G AG PG  G+ G  GD+G  G          G TG
Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071

Query: 856  PVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARG 915
              GLPG++G  G +G+ G  G  GP GP+G  G  G PG PG PGP G LG  G  G  G
Sbjct: 1072 DPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLG 1131

Query: 916  PPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPG 975
            PPG +GP G  G  G  G +G +G QG  G  G  G++G  GL+     PG RG    PG
Sbjct: 1132 PPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLL--RAPPGPRG---NPG 1186

Query: 976  LQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAG 1035
             QG  G  G  G PG PG +G  GD GP G  G+EG PG          PG  G +   G
Sbjct: 1187 AQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGP---------PGLPGAI-IPG 1236

Query: 1036 SVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSG 1095
              G  G PG RG PGAPG  G  G   + G+ G +G  G  G KG  G  G +GP GR G
Sbjct: 1237 QTGNRGPPGSRGSPGAPGPPGPPGSHVI-GIKGDKGSMGHPGPKGPPGTAGDMGPPGRLG 1295

Query: 1096 QTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVG 1155
              G PG  G  G PG +G PG KG+KG     G +GS GPPG IG  GP G RG  G + 
Sbjct: 1296 APGTPGLPGPRGDPGFQGFPGVKGEKGN---PGFLGSIGPPGPIGPKGPPGVRGDPGTLK 1352

Query: 1156 HLGLMGPDGEPGIPGYRGHQGQPGPSGLPG---PKGEKGYPGEDSTVLGPPGPRGEPGPV 1212
             + L G  G PG PG  G QG+PGP G PG   P G +G PG+D          G+PG  
Sbjct: 1353 IISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKD----------GKPGTP 1402

Query: 1213 GDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSE 1263
            G  GE+G  G++G  G  G  GL G  G++G  G P     +G    R S+
Sbjct: 1403 GPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQ 1453



 Score =  504 bits (1298), Expect = e-142
 Identities = 304/700 (43%), Positives = 365/700 (52%), Gaps = 59/700 (8%)

Query: 485  EYLRGPKGDTGPPGPPGPAGIPGP--SGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFS 542
            E L GP+GD G PGPPG  G PG    G RG +G+PG +G  G  G  G  GPKGDPG  
Sbjct: 785  EGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGI- 843

Query: 543  PG---QPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGI---PGFAGNIGSP 596
            PG      PGE G  G+ G  G  G  G +G  G+PG+ G PGE G+    GF G IG P
Sbjct: 844  PGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPP 903

Query: 597  GYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERG------IPGIRGKKGFKGRQ 650
            G PG  G  G  G+PG  G +G  G+PG  G+ G +G  G      + G +G+ G KG  
Sbjct: 904  GPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFA 963

Query: 651  GFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLP 710
            G PG+ G+RG  G+ G  GL G  GP G PG RG +G  G  G  G+ G  G  GN G+P
Sbjct: 964  GNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMP 1023

Query: 711  GIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRG--KSGPSGQTGDPGLQGPSGPPG 768
            G KG +G  G  G  G PG PG  G  G  G PG     + GP G TGDPGL G  G  G
Sbjct: 1024 GSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKG 1083

Query: 769  PEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGP---RGKPG 825
              G PG    PG  GP GP+G  G+ G PG PG  G  G+ G  G  G LGP   RG PG
Sbjct: 1084 EMGQPGP---PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPG 1140

Query: 826  QKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGL----PGEVGMTGSIGEKGERGSPG-- 879
              G+ G PGP G++G+ G  G  G  GE G  GL    PG  G  G+ G KG+RG+PG  
Sbjct: 1141 LPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFP 1200

Query: 880  ----------PLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSR 929
                        GP+G  G+ G+PGPPG+PG I    +PG  G RGPPGS+G  G  G  
Sbjct: 1201 GLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI----IPGQTGNRGPPGSRGSPGAPGPP 1256

Query: 930  GPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLP 989
            GP G      + G KG+KG  G  GP G  G  G+ G  G  G PG  GLPG  GD G  
Sbjct: 1257 GPPG----SHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQ 1312

Query: 990  GEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEP 1049
            G PG++G +G+   PG +G  GPPG  G    +G PG +GD GT   +   G P   G P
Sbjct: 1313 GFPGVKGEKGN---PGFLGSIGPPGPIGP---KGPPGVRGDPGTLKIISLPGSP---GPP 1363

Query: 1050 GAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGL---PGPEGIV 1106
            G PGE G+QG+ G  G PG  G  G  G+ G+ G PG  GP G  G  G    PGP G  
Sbjct: 1364 GTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSD 1423

Query: 1107 GIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKG 1146
            G+PG +G+ G  G        G V +R        S P+G
Sbjct: 1424 GLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEG 1463



 Score =  394 bits (1012), Expect = e-109
 Identities = 257/653 (39%), Positives = 318/653 (48%), Gaps = 97/653 (14%)

Query: 913  ARGPPGSQG----PKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGER 968
            A  P  S+G     KGQ    G  G  GE+G  G  G  G +G  GP GL      PG +
Sbjct: 22   AAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGL------PGPQ 75

Query: 969  GFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAK 1028
            G +G PGL GL GS G RG+ G PG  G  G  G PG  G  G  G  G SG +GE G  
Sbjct: 76   GPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFP 135

Query: 1029 GDVGTAGSVGGTGEPGLRGEPGAPGEE-----GLQGKDGLKGVPGGRGLPGEDGEKGEMG 1083
            G  GT G  G  G  GL+G+ GAP +E       +G  GL G PG +GLPG  G  G +G
Sbjct: 136  GLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVG 195

Query: 1084 LPGIIGPLGRSGQTGLPGPEGIVG--IPGQRGRPGKKGDKGQIGPTGEV----------- 1130
             PG  G  G  G  G  GP+G +G  + G +G  G KG  G  GP G V           
Sbjct: 196  PPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRT 255

Query: 1131 ---GSRGPPGKIGKSGPKGARGT--------RGAVGHLGLMGPDGEPGIPGYRGHQGQPG 1179
               G +G  G +G+ GP G  G         +GA G  GL G  G+ G+PG+ G +G  G
Sbjct: 256  DLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG 315

Query: 1180 PSGLPGPKGEKGYPGE-----------------------DSTVLGPPGPRGEPGPVGDQG 1216
              G PG  GE G  G+                       D    GPPGPRG  GP G  G
Sbjct: 316  NRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSG 375

Query: 1217 ERGEPGAEG-----YKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGA 1271
              G PG+ G      +G  G PGL+G+ G++G PG+    G  G  G  GS G  G  G 
Sbjct: 376  PPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDA-MGTPGSPGCAGSPGLPGSPGP 434

Query: 1272 PGPSG----KPGIPGLQGLLGPKGIQGYHGADGISGNPGKI--------GPPGKQGLPG- 1318
            PGP G    + G PG  GL G  G  G  G DG  G PG +        GPPG  GLPG 
Sbjct: 435  PGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGL 494

Query: 1319 --IRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHR-GAQG 1375
              ++G PGR G AG  G PG  G++GLPG PG  G +G+      PG++G++G     +G
Sbjct: 495  HGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGD------PGLKGEKGETLQPEG 548

Query: 1376 DQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLG 1435
              G  GDPGL+GQPG  G+ G+ G  G  G  GP+G+  + G  G +GP G  G+ G  G
Sbjct: 549  QVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPG 608

Query: 1436 REGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQMDINAAI 1488
              G  GP G  GP+GE G       QG +G PG PGPPG  GPR ++ ++  +
Sbjct: 609  PAGPAGPPGY-GPQGEPGL------QGTQGVPGAPGPPGEAGPRGELSVSTPV 654



 Score =  335 bits (860), Expect = 2e-91
 Identities = 205/477 (42%), Positives = 235/477 (49%), Gaps = 53/477 (11%)

Query: 484  MEYLRGPKGDTGPPGPPGP------------------------AGIPGPSGKRGPRGIPG 519
            M  L+G KG  GP GPPGP                         G+PG  GKRG  G PG
Sbjct: 977  MPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036

Query: 520  PHGNPGLPGLPGPKGPKGDPGFS----PGQP----VPGEKGDQGLSGLMGPPGMQGDKGL 571
              G PGLPG+ G +G KG+PG+S    PG P     PG  GD G  G MG PG  G  G 
Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGP 1096

Query: 572  KGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGP 631
             G  G PG PG  G+PG  G  G  G+ G +GL GP G  GP G  GF GSPG  G  G 
Sbjct: 1097 AGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGD 1156

Query: 632  EGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGP 691
            +G  GIPG  G+KG  G    P   G RG  G  G+ G  G  G PG PG +G++G  GP
Sbjct: 1157 QGRDGIPGPAGEKGETGLLRAPP--GPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP 1214

Query: 692  IGPAGI---PGPMGL--------SGNKGLPGIKGDKGEQGTAGELGEP--GYPGDKGAVG 738
             GP GI   PGP GL        +GN+G PG +G  G  G  G  G    G  GDKG++G
Sbjct: 1215 RGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMG 1274

Query: 739  LPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPG 798
             PGP G  G +G  G  G  G  G  G PGP G PG  G PG  G +G  G LG+ GPPG
Sbjct: 1275 HPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPG 1334

Query: 799  PPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVG 858
            P G KG  G  G  G    +   G PG  G  GEPG +G  G  G  GN+G  G  G  G
Sbjct: 1335 PIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPG 1394

Query: 859  LPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARG 915
              G+ G  G  GEKG +GS G  GP G  G+      PG+ G  G  G P     RG
Sbjct: 1395 KDGKPGTPGPAGEKGNKGSKGEPGPAGSDGL------PGLKGKRGDSGSPATWTTRG 1445



 Score =  240 bits (613), Expect = 8e-63
 Identities = 143/336 (42%), Positives = 170/336 (50%), Gaps = 16/336 (4%)

Query: 475  YEDLNTMLEMEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPG-LPGPK 533
            ++ +  +L    +RGP G  G PG PGP GI G  G+    GIPGP G  G  G L  P 
Sbjct: 1123 FKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGR---DGIPGPAGEKGETGLLRAPP 1179

Query: 534  GPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPG--FAG 591
            GP+G+PG    Q   G++G  G  GL G  G  GD G +G  G+ G PG  G+PG    G
Sbjct: 1180 GPRGNPG---AQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPG 1236

Query: 592  NIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQG 651
              G+ G PG +G  G  G PGP G+   IG  G+ G +G  G +G PG  G  G  GR G
Sbjct: 1237 QTGNRGPPGSRGSPGAPGPPGPPGSH-VIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLG 1295

Query: 652  FPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPG 711
             PG  G  GP G  G  G  G  G  G PG  GS+GP GPIGP G PG  G  G   +  
Sbjct: 1296 APGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIIS 1355

Query: 712  IKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEG 771
            + G  G  GT      PG PG +G  G PGPPG  G  GP G+ G  G  G  GP G +G
Sbjct: 1356 LPGSPGPPGT------PGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409

Query: 772  FPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQG 807
              G  G PG  G +G  GL G RG  G P    T+G
Sbjct: 1410 NKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445


>gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens]
          Length = 1712

 Score =  736 bits (1901), Expect = 0.0
 Identities = 478/1158 (41%), Positives = 568/1158 (49%), Gaps = 178/1158 (15%)

Query: 489  GPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPG-------PKGPKGDPGF 541
            G  G+ G PG  G  G+ G  G  GPRG  G  G+PG PGLP         KG +GDPGF
Sbjct: 308  GLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGF 367

Query: 542  SPGQPVPGEKGDQGLSGLMGPPGMQ---GD--KGLKGHPGLPGLPGEQGIPGFAGNIGSP 596
               Q  PG +G+ G  GL GPPG+    GD  +GL G  G  G  G+ GIP   G  G P
Sbjct: 368  PGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYG--GPP 425

Query: 597  GYPGRQGLAGPEGNPGPKGAQGFI-GSPGEAGQLGPEGERGIPGIRGKKGFKGRQG-FPG 654
            G  G++G  GP G PGP G  GF+ G  G  G+ G  G  G PG RG KG+KG  G    
Sbjct: 426  GPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRC 485

Query: 655  DFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKG 714
              GD    GL G PG  G  G  G PG +G  G  G  G  G PG  G+ GN G PG KG
Sbjct: 486  TEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKG 545

Query: 715  DKGE------QGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPG 768
             KG+      +G  G+ G PG PG KG  G PG  G+ G  G  G  GD G++GP G PG
Sbjct: 546  AKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGD-GIKGPPGDPG 604

Query: 769  PEGFPGDIGIPGQNGPEGP--KGLLGNRGPPGPPGLKGTQG---EEGPIGAFGEL----- 818
              G PG  G PG+ GP G    GL G RG PG  GL G  G     GP G  G++     
Sbjct: 605  YPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTD 664

Query: 819  -------------------GPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGL 859
                               GP+G PG     G PGP G KG  G  G  G  G  GP GL
Sbjct: 665  VKRAVGGDRQEAIQPGCIGGPKGLPG---LPGPPGPTGAKGLRGIPGFAGADGGPGPRGL 721

Query: 860  PGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIG---------PLGLPGH 910
            PG+ G       +G  G PG +GP+G KG +G PGP G PGPIG           GLPG 
Sbjct: 722  PGDAG------REGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGE 775

Query: 911  V--------GARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKT 962
            V        G  G PG  G KG  G RGP G  G QG+ G  G KG  G  GP G  G  
Sbjct: 776  VLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLY 835

Query: 963  GNPGERGFQGKPGLQG---LPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGES 1019
            G PG  GF G PG +G   LPG  G  GLPG+   RG  GD G PG +GM+G  G  G++
Sbjct: 836  GPPGLHGFPGAPGQEGPLGLPGIPGREGLPGD---RGDPGDTGAPGPVGMKGLSGDRGDA 892

Query: 1020 GLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEK 1079
            G  GE G  G  G  G  G  G PGL+G+ G+PG +G QG  GLKG PG  G  GE G  
Sbjct: 893  GFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFF 952

Query: 1080 GEMGLPGIIGPLGRSGQTGLPGPEGI--VGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPG 1137
            G  GL G+ G  G  G  G PGP G   V +PG +   G+KGD+G +G  G +G++G  G
Sbjct: 953  GIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQG 1012

Query: 1138 KIGKSGPKGARGTRGAVGHL----GLMGPDGEPGIPGYRGHQGQPGPSGLPG---PKGEK 1190
              G  G  G  G  G  GH+    G +G  G PG+PG+ G  G PG +G PG    +G+K
Sbjct: 1013 MPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDK 1072

Query: 1191 GYPG------------------EDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGV 1232
            G PG                  +   + G PG +GE G  G  G +G  G +G +G +G 
Sbjct: 1073 GAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGF 1132

Query: 1233 PGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGK---PGIPGLQGLLGP 1289
            PG+ G TG QGPPG  G  G  GL G  GS+G  G+ G PG  G    PG PGL G  G 
Sbjct: 1133 PGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGL 1192

Query: 1290 KGIQGYHGADG-----------ISGNPGKIGPPGK----------------------QGL 1316
            +GI+G HG  G           I G+PG  GPPG+                      QG 
Sbjct: 1193 RGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGA 1252

Query: 1317 PGIRGGPGRTGLAGAPG---PPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGA 1373
            PG RG PG  GL G PG   P  + G+ G  G+PGI G KG +G PG PG     G +G 
Sbjct: 1253 PGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGD 1312

Query: 1374 QGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGP 1433
             G+ G  G PG KG  G+ G QG  G  G PG KGP G+ G +G +GP G +G RG  GP
Sbjct: 1313 TGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGP 1372

Query: 1434 LG-------------------------REGIIGPTGRTGPRGEKGFRGETGPQGPRGQPG 1468
             G                         + G +GP GR GP G     GE GPQGP G+PG
Sbjct: 1373 KGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAP---GEMGPQGPPGEPG 1429

Query: 1469 PPGPPGAPGPRKQMDINA 1486
              G PG  GP+ +  ++A
Sbjct: 1430 FRGAPGKAGPQGRGGVSA 1447



 Score =  729 bits (1883), Expect = 0.0
 Identities = 486/1169 (41%), Positives = 559/1169 (47%), Gaps = 198/1169 (16%)

Query: 488  RGPKGDTGPPGPPG-PAGIPGPS---GKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSP 543
            RGPKG+ G PGPPG PA  P PS   G RG  G PG  G PG  G PG  G  G PG S 
Sbjct: 334  RGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSI 393

Query: 544  G-----QPVPGEKGDQGLSG-------LMGPPGMQGDKGLKGHPGLPGLPGEQG----IP 587
            G     + +PGE G +G  G         GPPG  G +G  G PGLPG PG  G    + 
Sbjct: 394  GDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLK 453

Query: 588  GFAGNIGSPGYPGRQGLAGPEG----------------------NPGPKGAQGFIGSPGE 625
            G  G  G PG PG  G  GP+G                       PGPKG  G  G PG 
Sbjct: 454  GAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGR 513

Query: 626  AGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGS 685
             G  G  G+ G+PG  G KG  G  G PG  G +G +    + G  G  G PG PG++G 
Sbjct: 514  KGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGD 573

Query: 686  VGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGM 745
             G          PG  GL G  GLPG  GD G +G  G+ G PG PG KG  G  GPPG+
Sbjct: 574  DGS---------PGRDGLDGFPGLPGPPGD-GIKGPPGDPGYPGIPGTKGTPGEMGPPGL 623

Query: 746  R--GKSGPSGQTGDPGLQGPSG---PPGPEGFPGDIGI-----------------PGQNG 783
               G  G  G  GD GL GP G   PPGP G PG I                   PG  G
Sbjct: 624  GLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIG 683

Query: 784  PEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVG 843
              GPKGL G  GPPGP G KG +G  G  GA G  GPRG PG  G  G PGP G    +G
Sbjct: 684  --GPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGF---IG 738

Query: 844  DQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPL-----GPQGEKGVMGYPGPPGV 898
             +G+ G +G  GP G PG +G+ G  G  GERG PG +     GP+G+ GV G PG  G+
Sbjct: 739  PRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGL 798

Query: 899  PGPIGP------LGLPGHVGARGPPGSQGPKGQRGSRGPDGLLG---------------- 936
            PG  GP       G+PG  G +G PG  GP GQ G  GP GL G                
Sbjct: 799  PGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGI 858

Query: 937  --EQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGL 994
               +G+ G +G+ GD G  GP G+ G +G+ G+ GF G+ G  G PG  G  G+PG PGL
Sbjct: 859  PGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGL 918

Query: 995  RG------LQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPG---- 1044
            +G      + G  G PG  G  G PG++GE+G  G PG KG  G  G  G  G+PG    
Sbjct: 919  KGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGP 978

Query: 1045 ----------LRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGII----GP 1090
                      ++GE G  G  GL+G  G KG+ G  G+PG  G  G  G PG I    G 
Sbjct: 979  PPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGD 1038

Query: 1091 LGRSGQTGLPG------PEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIG---- 1140
            +G  G  GLPG      P GI G PG  G  G KG  G+ G  GE+G+ G  G IG    
Sbjct: 1039 IGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTIN 1098

Query: 1141 ---KSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDS 1197
               + G KG RGT G  G  G  G  G  G  G+ G  G  G  G PG KG+ G+PG   
Sbjct: 1099 LPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPG--- 1155

Query: 1198 TVLGPPGPRGE------PGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPG-- 1249
             + GPPG +GE      PG  GD G  G PG  G+ G  G+ GL G  G +G PG PG  
Sbjct: 1156 -LTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSD 1214

Query: 1250 ---DQGEQGLKGERGSEGN-------------KGKKGAPGPSGKPGIPGLQGLLGP---- 1289
               D G  G  GERG  G              KG +GAPG  G PG PGLQG  G     
Sbjct: 1215 IHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPS 1274

Query: 1290 --KGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKG---SSGLP 1344
               G  G  GA GI G  G  GPPG  G   + G  G TG  GAPG PG KG    SG  
Sbjct: 1275 NISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQ 1334

Query: 1345 GSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCG---DPGLKGQPGEYGVQGLTGFQ 1401
            G PG+ G  GE+G  G+ G  G  G  GA GD+GP G   DPG  G PG  G  G+ G  
Sbjct: 1335 GRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIP 1394

Query: 1402 GF----PGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGE 1457
                  PG  GP+G  G  G  G  GP G  G  G  G  G  GP GR G     GFRG+
Sbjct: 1395 QKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGD 1454

Query: 1458 TGP---QGPRGQ------PGPPGPPGAPG 1477
             GP   QGP GQ      PG PG PG PG
Sbjct: 1455 EGPIGHQGPIGQEGAPGRPGSPGLPGMPG 1483



 Score =  721 bits (1861), Expect = 0.0
 Identities = 477/1162 (41%), Positives = 561/1162 (48%), Gaps = 183/1162 (15%)

Query: 487  LRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQP 546
            L+G KGD G  G PG   + GP G  G RG+ G  G  G+PG PG  GP+G PG+     
Sbjct: 83   LQGRKGDKGERGAPG---VTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNG 139

Query: 547  VPGEKGDQ---GLSGLMGPPGMQGDKGLK---------------GHPGLPGLPGEQGIPG 588
              G+ G Q   G  G  GPPG QG KG K               G PG PGL G QG PG
Sbjct: 140  TQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERDRYRGEPGEPGLVGFQGPPG 199

Query: 589  FAGNIGSPGYPGRQGLAGPEGNPGPKGAQ-----GFIGSPGEAGQLGPEGERGIPG---- 639
              G++G  G  G  G  GP G PGPKG Q     GF G  GE G +G  G  GIP     
Sbjct: 200  RPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSDTLH 259

Query: 640  --------------IRGKKG-----------FKGRQGFPGDFGDRGPAGLDGSPGLVGGT 674
                           +G+KG            KG +G  G  G RG  GL G  G  G  
Sbjct: 260  PIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQK 319

Query: 675  GPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGI-KGDKGEQGTAGELGEPGYPGD 733
            G  G  G +G  GP GP G AG PGP GL      P + KG +G+ G  G  GEPG  G+
Sbjct: 320  GSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGE 379

Query: 734  KGAVGLPGPPGMR-----------GKSGPSGQTGDPGLQ----GPSGPPGPEGFPGDIGI 778
             G  GLPGPPG+            G+ GP G  GDPG+     GP GP G  G PG  G+
Sbjct: 380  PGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGL 439

Query: 779  PGQNGPEG-PKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGP-------------RGKP 824
            PG  GP+G   GL G +G  G PGL G+ G  GP G  G+ G               G P
Sbjct: 440  PGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLP 499

Query: 825  GQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTG---------SIGEKGER 875
            G KG+AG  G  G KG+ GD G  G  G  G  G+PG +G  G         +I  KGER
Sbjct: 500  GPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGER 559

Query: 876  GSPGPLGPQGEKGVMGYPGP------PGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSR 929
            G PG  G  G KG  G PG       PG+PGP G  G+ G  G  G PG  G KG  G  
Sbjct: 560  GQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGD-GIKGPPGDPGYPGIPGTKGTPGEM 618

Query: 930  GPDGLLGEQGIQGAKGEKGDQGKRGPHGLI---GKTGNPGE------------------- 967
            GP G LG  G++G +G  GD G  GP G +   G  G PG+                   
Sbjct: 619  GPPG-LGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAI 677

Query: 968  -----RGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGP------------PGEMGME 1010
                  G +G PGL G PG TG +GL G PG  G  G  GP            PG  G  
Sbjct: 678  QPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFI 737

Query: 1011 GPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGE-----PGAPGEEGLQGKDGLKG 1065
            GP G++G  GL G  G+ G +G  G  G  GE GL GE     PG  G+ G+ G+ GLKG
Sbjct: 738  GPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKG 797

Query: 1066 VPGGRGLPGEDGEKGEMGLPGIIGP---LGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKG 1122
            +PG RG PG  G +G  G+PG+ G     G SGQ GL GP G+ G PG  G+ G  G  G
Sbjct: 798  LPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPG 857

Query: 1123 QIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSG 1182
              G  G  G RG PG  G  GP G +G  G  G  G  G  G PG PG++G  G P   G
Sbjct: 858  IPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMP---G 914

Query: 1183 LPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQ 1242
             PG KG++G PG D    G PG +G PG  G +GE G  G  G KG  G PG +G+ G  
Sbjct: 915  TPGLKGDRGSPGMDG-FQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDP 973

Query: 1243 GPPGEP--------------GDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQG-LL 1287
            GPPG P              GD+G  GLKG  G++G +G  G PG SG PG+PG  G + 
Sbjct: 974  GPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIK 1033

Query: 1288 GPKGIQGYHGADGISGNPGKIGPPGKQGLPGI------RGGPGRTGLAGAPGPPGVKGSS 1341
            G KG  G  G  G+ G PG  GPPG  G PG       +G PGR GL G  G  G  G  
Sbjct: 1034 GVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDI 1093

Query: 1342 G----LPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGL 1397
            G    LPG PG+   KGE+G  G PG++G  G +G +GD G  G  G+ G  G  G++G 
Sbjct: 1094 GDTINLPGRPGL---KGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQ 1150

Query: 1398 TGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGE 1457
            TGF G  GP G +G+ G +G+ G KG  G  G  G  G  G+ G  G  G  G KGF G 
Sbjct: 1151 TGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGS 1210

Query: 1458 TGP--QGPRGQPGPPGPPGAPG 1477
             G    G  G PGPPG  G PG
Sbjct: 1211 PGSDIHGDPGFPGPPGERGDPG 1232



 Score =  719 bits (1857), Expect = 0.0
 Identities = 478/1212 (39%), Positives = 588/1212 (48%), Gaps = 223/1212 (18%)

Query: 483  EMEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLP-----------GLPG 531
            E +  RG  G+ G  G  GP G PG  G+ GP G PG  G PG P           G  G
Sbjct: 178  ERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYG 237

Query: 532  PKGPKGDPG----------------------FSPGQPVPGEKGDQGLSGLMGPPGMQGDK 569
             KG KGD G                      F P Q   GEKG +G  G+ G   ++G++
Sbjct: 238  VKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQ-YKGEKGSEGEPGIRG-ISLKGEE 295

Query: 570  GLKGHPGL---PGLPGEQGIPGFAGNIGSPGYPGRQGLAGPE---GNPGP---------- 613
            G+ G PGL   PGL GE+G PG  G+ G  GY G  G  GP+   G+PGP          
Sbjct: 296  GIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHP 355

Query: 614  ---KGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFK-----GRQGFPGDFGDRGPAGLD 665
               KGA+G  G PG  G+ G +GE G PG+ G  G        R+G PG+ G +G  G  
Sbjct: 356  SLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDP 415

Query: 666  GSPGLVGG-------TGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGE 718
            G P L GG        GPPG PGL G  GP G +   G+ G  G +G  GLPG  G +G 
Sbjct: 416  GIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFL--FGLKGAKGRAGFPGLPGSPGARGP 473

Query: 719  QGTAGELGE----PGYPGDKGAVGLPGP---PGMRGKSGPSGQTGDPGLQGPSGPPGPEG 771
            +G  G+ GE     G    KG  GLPGP    G+ G+ G  G  GDPG  G  G PG +G
Sbjct: 474  KGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKG 533

Query: 772  FPGDIGIPGQNGPEGPKGLL---GNRGPPGPPGLKGTQGEEGPIGAFG-----------E 817
             PG+IG PG  G +G    +   G RG PG PG+ G +G++G  G  G            
Sbjct: 534  VPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPG 593

Query: 818  LGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGS---IGEKGE 874
             G +G PG  GY G PG +G  GE+G  G +G  G  G  G PG+ G+ G    +G  G 
Sbjct: 594  DGIKGPPGDPGYPGIPGTKGTPGEMGPPG-LGLPGLKGQRGFPGDAGLPGPPGFLGPPGP 652

Query: 875  RGSPGPLGPQ---------------------GEKGVMGYPGPPGVPGPIGPLGLPGHVGA 913
             G+PG +                        G KG+ G PGPPG  G  G  G+PG  GA
Sbjct: 653  AGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGA 712

Query: 914  RGPPGSQ---GPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGF 970
             G PG +   G  G+ G  GP G +G +G +GA G  G  G  GP GL G  G PGERG 
Sbjct: 713  DGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGL 772

Query: 971  QGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPP---GEMGMEGPPGTEGESGLQGE--- 1024
             G+  L   PG  GD G+PG+PGL+GL GD GPP   G  GM G PG +G+ GL G    
Sbjct: 773  PGEV-LGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQ 831

Query: 1025 ------------PGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGL 1072
                        PGA G  G  G  G  G  GL G+ G PG+ G  G  G+KG+ G RG 
Sbjct: 832  PGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGD 891

Query: 1073 PGEDGEKGEMGLPGIIGPLGRSGQTGL------PGPEGIVGIPGQRGRPGKKGDKGQ--- 1123
             G  GE+G  G PG  G  G  G  GL      PG +G  G+PG +GRPG  G KG+   
Sbjct: 892  AGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGF 951

Query: 1124 ---------IGPTGEVGSRGPPGKIGK-----------SGPKGARGTRGAVGHLGLMGPD 1163
                      G  G  GSRG PG  G             G KG  G  G  G+LG  G  
Sbjct: 952  FGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQ 1011

Query: 1164 GEPGIPGYRGHQGQPG-PSGLPGPKGEKGYPGEDST-----VLGPPGPRGEPGPVGDQGE 1217
            G PGIPG  G  G PG P  + G KG+ G PG         V GPPG  G PG +G +G+
Sbjct: 1012 GMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGD 1071

Query: 1218 RGEPGAEGYKGHVGVPGLRGATGQQ-GPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSG 1276
            +G PG  G  G +G  G  G  G     PG PG +GE+G  G  G +G  G+KG  G  G
Sbjct: 1072 KGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIG 1131

Query: 1277 KPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGG---PGRTGLAGAPG 1333
             PGI G+ G+ GP G++G  G  G++G PG  G  G+ GLPG +G    PG  GL G PG
Sbjct: 1132 FPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPG 1191

Query: 1334 PPGVKGSSGLPGS--------------PGIQGPKGEQG-------LPGQPGIQGKRGHRG 1372
              G++G  GLPG+              PG  GP GE+G       LPG  G+ G++G +G
Sbjct: 1192 LRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQG 1251

Query: 1373 AQGDQGPCGDPGLK------------GQPGEYGVQGLTGFQGFPGPKGP---------EG 1411
            A G++GP G PGL+            G PG+ G  G+ G +G+ GP GP         +G
Sbjct: 1252 APGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKG 1311

Query: 1412 DAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGP------QGPRG 1465
            D G  G  G  G  G  G++GP GR G+ G  G  GPRGE+GF G TGP      +GP+G
Sbjct: 1312 DTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKG 1371

Query: 1466 QPGPPGPPGAPG 1477
              G PG PGAPG
Sbjct: 1372 PKGDPGFPGAPG 1383



 Score =  688 bits (1775), Expect = 0.0
 Identities = 458/1163 (39%), Positives = 555/1163 (47%), Gaps = 201/1163 (17%)

Query: 508  PSGKRGPRGIPGPHGNPGLPGLPGPKGPK---GDPGFSPGQPVPGEKGDQGLSGLMGPPG 564
            P G R   G    +   G  G PGP GP+   G PG      + G KGD+G  G  G  G
Sbjct: 41   PCGGRDCSGGCQCYPEKGGRGQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTG 100

Query: 565  MQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPG 624
             +GD G +G  G PG  G  G PG  G  G PGY G  G  G  G  GP G++GF G PG
Sbjct: 101  PKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPG 160

Query: 625  EAGQLGPEGE------------RGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVG 672
              G  G +GE            RG PG  G  GF+G  G PG  G  GP G  G PG  G
Sbjct: 161  PQGPKGQKGEPYALPKEERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPG 220

Query: 673  GTGPP--------GFPGLRGSVGPVGPIGPAGIP--------GPMGLS----------GN 706
              GP         GF G++G  G VG  GP GIP         P G++          G+
Sbjct: 221  PPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGS 280

Query: 707  KGLPGIKGD--KGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPS 764
            +G PGI+G   KGE+G  G  G  GYPG  G  G PG  G RG  G  G  G  G +G +
Sbjct: 281  EGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEA 340

Query: 765  GPPGPEGFP-------------GDIGIPGQNGPEGPKGLLGNRGPPGPPGL--------K 803
            G PGP G P             GD G PG  G  G +G  G+ G PGPPGL        +
Sbjct: 341  GDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRR 400

Query: 804  GTQGEEGPIGAFGELG----PRGKPGQKGYAGEPGPEGLKGEVGDQGNI-GKIGETGPVG 858
            G  GE GP G  G+ G      G PG  G  G PGP GL G  G  G + G  G  G  G
Sbjct: 401  GLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAG 460

Query: 859  LPGEVGMTGSIGEKGERGSPGPLG-PQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPP 917
             PG  G  G+ G KG +G  G     +G++ + G PG PG  G  G  G PG  G RG P
Sbjct: 461  FPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDP 520

Query: 918  GSQGPKGQRGSRGPDGLLGEQGIQGA---------KGEKGDQGKRGPHGLIGKTGNPGER 968
            G  G  G  G +G  G +G  G +GA         KGE+G  G  G  G+ G  G+PG  
Sbjct: 521  GQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRD 580

Query: 969  GFQGKPGLQGLPGS-----TGDRGLPGEPGLRGLQGDVGPP--GEMGMEGPPGTEGESGL 1021
            G  G PGL G PG       GD G PG PG +G  G++GPP  G  G++G  G  G++GL
Sbjct: 581  GLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGL 640

Query: 1022 QGEPGAKGDVGTAG-------------SVGG--------------TGEPGLRGEPGAPGE 1054
             G PG  G  G AG             +VGG               G PGL G PG  G 
Sbjct: 641  PGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGA 700

Query: 1055 EGLQGKDGLKGV---PGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGI---VGI 1108
            +GL+G  G  G    PG RGLPG+ G +G  G PG IGP G  G  GLPGP+G    +G+
Sbjct: 701  KGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGL 760

Query: 1109 PGQRGRPGKKGDKGQI-----GPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPD 1163
            PG  G PG++G  G++     GP G+ G  G PG  G  G +G  G RG+ G  G+ G  
Sbjct: 761  PGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLK 820

Query: 1164 GEPGIP---------------GYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGE 1208
            G+PG+P               G+ G  GQ GP GLPG  G +G PG+     G PG  G 
Sbjct: 821  GQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGD----RGDPGDTGA 876

Query: 1209 PGPVGDQ---GERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGN 1265
            PGPVG +   G+RG+ G  G +GH G PG +G  G  G PG  GD+G  G+ G +G  G 
Sbjct: 877  PGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGL 936

Query: 1266 KGKKGAPGPSGKP---GIPGLQGLL----------------------------------- 1287
            KG+ G PG  G+    GIPGL+GL                                    
Sbjct: 937  KGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDE 996

Query: 1288 GPKGIQGYHGADGISGNPGKIGPPGKQGLP-------GIRGGPGRTGLAGAPGPPGVKGS 1340
            GP G++GY GA GI G PG  G  G  GLP       G++G  G  G+ G PG PGV G 
Sbjct: 997  GPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGP 1056

Query: 1341 SGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPC----GDPGLKGQPGEYGVQG 1396
             G+ G PG  G +G++G PG+ G+ G+ G  G  GD G      G PGLKG+ G  G+ G
Sbjct: 1057 PGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPG 1116

Query: 1397 LTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRG 1456
            L GF G  G +G  G  GI G++G +GP G +G T      G  G TG  G +GE G  G
Sbjct: 1117 LKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQT------GFPGLTGPPGSQGELGRIG 1170

Query: 1457 ETGPQGPRGQPGPPGPPGAPGPR 1479
              G +G  G PG PG PG PG R
Sbjct: 1171 LPGGKGDDGWPGAPGLPGFPGLR 1193



 Score =  648 bits (1671), Expect = 0.0
 Identities = 438/1071 (40%), Positives = 514/1071 (47%), Gaps = 172/1071 (16%)

Query: 491  KGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGL---------PGPKGPKGDPGF 541
            KG  G PGP G AGI G  G++G RG PG HG PG PGL         PGPKG KGD   
Sbjct: 493  KGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRT 552

Query: 542  --------SPGQP-VPGEKGDQG---------LSGLMGPPGMQGDKGLKGHPGLPGLPGE 583
                     PG P VPG KGD G           GL GPPG  G KG  G PG PG+PG 
Sbjct: 553  ITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPG-DGIKGPPGDPGYPGIPGT 611

Query: 584  QGIPGFAG--NIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQL------------ 629
            +G PG  G   +G PG  G++G  G  G PGP G  G  G  G  GQ+            
Sbjct: 612  KGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGG 671

Query: 630  ------------GPEGERGIPGI---RGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGT 674
                        GP+G  G+PG     G KG +G  GF G  G  GP GL G  G  G  
Sbjct: 672  DRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFP 731

Query: 675  GPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGE-----QGTAGELGEPG 729
            GPPGF G RGS G VG  GP G PGP+GL G  G PG +G  GE      G  G+ G PG
Sbjct: 732  GPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPG 791

Query: 730  YPGDKGAVGLPGPPGMRGKSGPSGQTG---DPGLQGPSGPPGPEGFPGDIGIPGQNGPEG 786
             PG KG  G  GPPG RG  G  G  G    PGL GPSG PG  G PG  G PG  G EG
Sbjct: 792  QPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEG 851

Query: 787  PKGLLG---------------NRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAG 831
            P GL G               + G PGP G+KG  G+ G  G  GE G  G PG KG  G
Sbjct: 852  PLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDG 911

Query: 832  EPGPEGLKGEVGDQGNIG---------------KIGETGPVGLPGEVGMTGSIGEKGERG 876
             PG  GLKG+ G  G  G                 GE G  G+PG  G+ G  G KG RG
Sbjct: 912  MPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRG 971

Query: 877  SPGPLGPQ--------------------------GEKGVMGYPGPPGVPGPIGPLGLPGH 910
             PGP GP                           G KG+ G PG PG+ G  G  G PGH
Sbjct: 972  DPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGH 1031

Query: 911  V----GARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPG 966
            +    G  G PG  G  G  G  GP G+ G  G  G++G+KG  G+ G +G IG TG+ G
Sbjct: 1032 IKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFG 1091

Query: 967  ERG----FQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPG---EMGMEGPPGTEGES 1019
            + G      G+PGL+G  G+TG  GL G  G +G +GD+G PG     G++GPPG +G++
Sbjct: 1092 DIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQT 1151

Query: 1020 G---LQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGED 1076
            G   L G PG++G++G  G  GG G+ G  G PG PG  GL+G  GL G+PG +G PG  
Sbjct: 1152 GFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSP 1211

Query: 1077 GEK--GEMGLPGIIGPLGRSGQTG-LPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSR 1133
            G    G+ G PG  G  G  G+   LPGP   VG+PGQ+G  G  G++G   P G  G +
Sbjct: 1212 GSDIHGDPGFPGPPGERGDPGEANTLPGP---VGVPGQKGDQGAPGERG---PPGSPGLQ 1265

Query: 1134 GPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYP 1193
            G PG    S   GA G +GA G  GL G         YRG  G PG + LPG KG+ G P
Sbjct: 1266 GFPGITPPSNISGAPGDKGAPGIFGLKG---------YRGPPGPPGSAALPGSKGDTGNP 1316

Query: 1194 GEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGE 1253
            G        PG  G  G  GD G +G PG  G  G  G  G +G  G  GP G  GD+G 
Sbjct: 1317 GA-------PGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGP 1369

Query: 1254 QGLKGERGSEGNKGKKGAPGPSG-------KPGIPGLQGLLGPKGIQGYHGADGISGNPG 1306
            +G KG+ G  G  G  GAPG +G       +PG  G QG  GP G  G  G  G  G PG
Sbjct: 1370 KGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPG 1429

Query: 1307 KIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQG 1366
              G PGK G  G  G     G  G  GP G +G  G  G+PG  G  G  G+PG+    G
Sbjct: 1430 FRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGMPGRSVSIG 1489

Query: 1367 KRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVG 1417
                + +Q DQ P    G+      Y    L  F+G    K    D G+ G
Sbjct: 1490 YLLVKHSQTDQEPMCPVGMNKLWSGY---SLLYFEG--QEKAHNQDLGLAG 1535



 Score =  602 bits (1552), Expect = e-171
 Identities = 382/912 (41%), Positives = 462/912 (50%), Gaps = 120/912 (13%)

Query: 487  LRGPKGDTGPPGPPGPAGIPGPSGK--------RGPRGIPGPHGNPGLPGLPGPKGPKGD 538
            ++GP GD G PG PG  G PG  G         +G RG PG  G PG PG  GP GP G 
Sbjct: 596  IKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGT 655

Query: 539  PG-----FSPGQPVPGEK----------GDQGLSGLMGPPGMQGDKGLKGHPGLPGL--- 580
            PG         + V G++          G +GL GL GPPG  G KGL+G PG  G    
Sbjct: 656  PGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGG 715

Query: 581  PGEQGIPGFAGNIGSPGYPG---------RQGLAGPEGNPGPKGAQGFIGSPGEAG---- 627
            PG +G+PG AG  G PG PG           GL GP+G+PGP G  G  G PGE G    
Sbjct: 716  PGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGE 775

Query: 628  ----QLGPEGE---------RGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGT 674
                Q GP G+         +G+PG RG  GF+G QG PG  G +G  GL G  G  G  
Sbjct: 776  VLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLY 835

Query: 675  GPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPG------------IKGDKGEQGTA 722
            GPPG  G  G+ G  GP+G  GIPG  GL G++G PG            + GD+G+ G  
Sbjct: 836  GPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFT 895

Query: 723  GELGEPGYPGDKGAVGLPGPPGM---RGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIP 779
            GE G PG PG KG  G+PG PG+   RG  G  G  G PGL+G  G PG +G  G  GIP
Sbjct: 896  GEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIP 955

Query: 780  GQNGPEGPKGLLGNRGPPGPPG-----------LKGTQGEEGPIGAFGELGPRG---KPG 825
            G  G  G  G  G+RG PGPPG           +KG +G+EGP+G  G LG +G    PG
Sbjct: 956  GLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPG 1015

Query: 826  QKGYAGEPGP-------EGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSP 878
              G +G PG        +G+KG++G  G  G  G  G  G PG  G  G IG +G++G+P
Sbjct: 1016 IPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAP 1075

Query: 879  GPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQ 938
            G  G  GE G  G  G  G    I   G PG  G RG  G  G KG  G +G +G +G  
Sbjct: 1076 GRAGLYGEIGATGDFGDIG--DTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFP 1133

Query: 939  GIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGK---PGLQGLPGSTGDRGLPGEPGLR 995
            GI G  G +G  G +G  G  G TG PG +G  G+   PG +G  G  G  GLPG PGLR
Sbjct: 1134 GITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLR 1193

Query: 996  GLQGDVGPPGEMGMEGPPGTE--GESGLQGEPGAKGDVGTAGSVGG-TGEPGLRGEPGAP 1052
            G++G  G PG  G  G PG++  G+ G  G PG +GD G A ++ G  G PG +G+ GAP
Sbjct: 1194 GIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAP 1253

Query: 1053 GEEGLQGKDGLKGVPG------GRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIV 1106
            GE G  G  GL+G PG        G PG+ G  G  GL G  GP G  G   LPG +G  
Sbjct: 1254 GERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDT 1313

Query: 1107 GIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGT---RGAVGHLGLMGPD 1163
            G PG  G PG KG  G  GP G  G  G PG+ G  G +G  G     GAVG  G  GP 
Sbjct: 1314 GNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPK 1373

Query: 1164 GEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGA 1223
            G+PG PG  G  G PG +G+P     +  PG     +GP G RG PG  G+ G +G PG 
Sbjct: 1374 GDPGFPGAPGTVGAPGIAGIPQKIAVQ--PG----TVGPQGRRGPPGAPGEMGPQGPPGE 1427

Query: 1224 EGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGL 1283
                     PG RGA G+ GP G  G     G +G+ G  G++G  G  G  G+PG PGL
Sbjct: 1428 ---------PGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGL 1478

Query: 1284 QGLLGPKGIQGY 1295
             G+ G     GY
Sbjct: 1479 PGMPGRSVSIGY 1490



 Score =  331 bits (849), Expect = 3e-90
 Identities = 222/536 (41%), Positives = 265/536 (49%), Gaps = 76/536 (14%)

Query: 484  MEYLRGPKGDTGPPGPPG---PAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPG 540
            M+ ++G KGD GP G  G     GI G  G  G  GIPG  G PG   + G KG  G PG
Sbjct: 986  MKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPG--HIKGVKGDIGVPG 1043

Query: 541  FSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSP-GYP 599
              PG  +PG  G  G  G+ G PG  G +G KG PG  GL GE G  G  G+IG     P
Sbjct: 1044 I-PG--LPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLP 1100

Query: 600  GRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDR 659
            GR GL G  G  G  G +GF G  G  G +G  G  G+ G++G  G KG+ GFPG  G  
Sbjct: 1101 GRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPP 1160

Query: 660  GPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQ 719
            G  G  G  GL GG G  G+P            G  G+PG  GL G +GL G+ G KG  
Sbjct: 1161 GSQGELGRIGLPGGKGDDGWP------------GAPGLPGFPGLRGIRGLHGLPGTKGFP 1208

Query: 720  GTAGE--LGEPGYPGDKGAVGLPGP----PGMRGKSGPSGQTGDPGLQGPSGPPGPEGFP 773
            G+ G    G+PG+PG  G  G PG     PG  G  G  G  G PG +GP G PG +GFP
Sbjct: 1209 GSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFP 1268

Query: 774  GDI------GIPGQNGPEGPKGLLGNRGPPGPPG---LKGTQGEEGPIGA---------F 815
            G        G PG  G  G  GL G RGPPGPPG   L G++G+ G  GA          
Sbjct: 1269 GITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWA 1328

Query: 816  GELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGER 875
            G+ GP+G+PG  G  GE GP G +G +G+ G  G +G+ GP G  G+ G  G+ G  G  
Sbjct: 1329 GDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAP 1388

Query: 876  G----------SPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQ 925
            G           PG +GPQG +G    PG PG  GP GP G PG    RG PG  GP+G+
Sbjct: 1389 GIAGIPQKIAVQPGTVGPQGRRGP---PGAPGEMGPQGPPGEPGF---RGAPGKAGPQGR 1442

Query: 926  RGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPG 981
             G     G  G            D+G  G  G IG+ G PG     G PGL G+PG
Sbjct: 1443 GGVSAVPGFRG------------DEGPIGHQGPIGQEGAPGR---PGSPGLPGMPG 1483



 Score =  278 bits (710), Expect = 4e-74
 Identities = 172/437 (39%), Positives = 211/437 (48%), Gaps = 22/437 (5%)

Query: 475  YEDLNTMLEMEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKG 534
            + D+   + +    G KG+ G  G PG  G  G  G  G  G PG  G  G+ G PG KG
Sbjct: 1090 FGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKG 1149

Query: 535  PKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIG 594
              G PG +      GE G  GL G  G  G  G  GL G PGL G+ G  G+PG  G  G
Sbjct: 1150 QTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPG 1209

Query: 595  SPGYPGRQGLAGPEGNPGPKGAQGFIGS----PGEAGQLGPEGERGIPGIRGKKGFKGRQ 650
            SPG      + G  G PGP G +G  G     PG  G  G +G++G PG RG  G  G Q
Sbjct: 1210 SPG----SDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQ 1265

Query: 651  GFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLP 710
            GFP   G   P+ + G+P   G  G PG  GL+G  GP GP G A +PG  G +GN G P
Sbjct: 1266 GFP---GITPPSNISGAP---GDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAP 1319

Query: 711  GIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPE 770
            G  G KG  G +G  G PG  G  G  G  G  G  G +GP+G  GD G +GP G PG  
Sbjct: 1320 GTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFP 1379

Query: 771  GFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYA 830
            G PG +G PG  G      +         PG  G QG  GP GA GE+GP+G PG+ G+ 
Sbjct: 1380 GAPGTVGAPGIAGIPQKIAV--------QPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFR 1431

Query: 831  GEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVM 890
            G PG  G +G  G     G  G+ GP+G  G +G  G+ G  G  G PG  G     G +
Sbjct: 1432 GAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGMPGRSVSIGYL 1491

Query: 891  GYPGPPGVPGPIGPLGL 907
                      P+ P+G+
Sbjct: 1492 LVKHSQTDQEPMCPVGM 1508



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 33/87 (37%), Positives = 38/87 (43%), Gaps = 6/87 (6%)

Query: 1397 LTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRG 1456
            L G + F  P G    +G       KG  G  G  GP G  G  G  G  G +G KG +G
Sbjct: 32   LAGVKKFDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQGYNGPPGLQGFPGLQGRKGDKG 91

Query: 1457 E------TGPQGPRGQPGPPGPPGAPG 1477
            E      TGP+G  G  G  G PGA G
Sbjct: 92   ERGAPGVTGPKGDVGARGVSGFPGADG 118


>gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo
            sapiens]
          Length = 1691

 Score =  734 bits (1895), Expect = 0.0
 Identities = 469/1130 (41%), Positives = 558/1130 (49%), Gaps = 170/1130 (15%)

Query: 488  RGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGN---PGLPGLPGPKGPKGDPGF--- 541
            +G KG+ G PG PGP G  G  G +GP G  G  G    PGL G  G +G KGD G    
Sbjct: 287  KGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGP 346

Query: 542  -------------SPGQP----VPGEKGDQGLSGLMGPPGMQGDKGLKGHPG------LP 578
                         +PG P    +PG KGD+G+ GL GP G+ G   L G PG       P
Sbjct: 347  DVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFP 406

Query: 579  GLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFI--------GSPGEAGQLG 630
            GL G+QG PG    IG+ G PGR GL GP G PGP   +           G PG  G+ G
Sbjct: 407  GLKGDQGNPGRT-TIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQG 465

Query: 631  PEGERGIPGIRGKKGFKG------RQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRG 684
            P+G  G+ GI+G  GF          G PG+ G  GP GL G PGL G  G  G  G +G
Sbjct: 466  PKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQG 525

Query: 685  SVGPVGPIGPAGIPGPMGLSGN------KGLPGIKGDKGEQGTAGELGEPGYPGDKGAVG 738
              G  G +GP G  GP G  G       +G+PG +GD G QG  G +GEPG  G  G  G
Sbjct: 526  PAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPG 585

Query: 739  LPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPG 798
            LPG PG  G+  P G+ G PGL G  G PGP G PG+ G+PG  GP G  G  G  G PG
Sbjct: 586  LPGLPGDGGQGFP-GEKGLPGLPGEKGHPGPPGLPGN-GLPGLPGPRGLPGDKGKDGLPG 643

Query: 799  PPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVG 858
              GL G++G   P    G  GP G PG  G+   PGP+G +G                  
Sbjct: 644  QQGLPGSKGITLPCIIPGSYGPSGFPGTPGF---PGPKGSRG------------------ 682

Query: 859  LPGEVGMTGSIGEKGERGSPGPL---------GPQGEKGVMGYPGPPG---VPGPIGPLG 906
            LPG  G  GS G KGE GSPG +         GP+GEKG+ G+PG PG   +PG IG  G
Sbjct: 683  LPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPG 742

Query: 907  LPGHVGARGP-----PGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGK 961
            LPG  GA G       G+ G +G +G  G  G LG+ G+ G KG  G  G  GP G  G 
Sbjct: 743  LPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGS 802

Query: 962  TGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGL 1021
             G PG+ G  G PG  G  G  G  GLPG PG  G+ G  G  G  G +GPPG+  + GL
Sbjct: 803  PGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGL 862

Query: 1022 QGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGE 1081
             G  G  G+ G  G  G  G PG+ G P   G +G +G  G  G PG  GLPG  G +G 
Sbjct: 863  PGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGL 922

Query: 1082 MGLPGIIGPLGRSGQTGLPGPEGI------VGIP---------------------GQRGR 1114
             G+PG  G +G SG+ G PG +G       VGIP                     G  G 
Sbjct: 923  KGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGF 982

Query: 1115 PGKKGDKGQIG---PTGEVGSRGPPGKI----GKSGPKGARGTRGAVGHLGLMGPDGEPG 1167
            PG +GDKG+ G   P G  G+ G PG I    GK GP G  G RG  G  G  G  G PG
Sbjct: 983  PGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPG 1042

Query: 1168 IPG------YRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEP 1221
            +PG       RG  G PG SGLPG KG+ G   E S   G PGP+G+PG  G +G +G  
Sbjct: 1043 MPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEIS---GSPGPKGQPGESGFKGTKGRD 1099

Query: 1222 GAEG---YKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKP 1278
            G  G   + G+ G  G  G +G  G PG PG  G  G++GE G  G+ G +GA GP G P
Sbjct: 1100 GLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSP 1159

Query: 1279 GIPGLQGLLGPKGIQGYHGADGISGNPGKIGP-----PGKQGLPGIRGGPGRTGLA-GAP 1332
            G+ G +G  G  G+ G +G  G  G  G  GP     PG  GLPG +G  G  G+  GAP
Sbjct: 1160 GLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAP 1219

Query: 1333 GPPGVKGSSGLPGSPGIQGPKGEQGLPG---------QPGIQGKRGHRGAQGDQGPCGDP 1383
            G PG++G  G  G PG+QGP G  G PG         QPG  G+ G  G +G  GP G P
Sbjct: 1220 GKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPP 1279

Query: 1384 GLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPT 1443
            G  G     G  G  GF G PGPKGP+GD GI G SG  G +G +G     G  G +G  
Sbjct: 1280 GPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMR---GEPGFMGTP 1336

Query: 1444 GRTGPRGEKGFRGETGPQGPRGQPG----------------PPGPPGAPG 1477
            G+ GP G+ GF G  G  GPRG  G                PPGP G PG
Sbjct: 1337 GKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPG 1386



 Score =  731 bits (1886), Expect = 0.0
 Identities = 506/1293 (39%), Positives = 597/1293 (46%), Gaps = 307/1293 (23%)

Query: 487  LRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPG---PHGNPGLPGLPGPKGPKGDPGFSP 543
            L G KG+ G PG  GP G   P G +GP G+PG    +G PG PG PGP+GP G  G + 
Sbjct: 72   LSGLKGERGFPGLLGPYG---PKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNG 128

Query: 544  GQPVPGEKGDQGLSGLMGPPGMQGD--------------KGLKGHPGLPGL---PGEQGI 586
             Q   G  G  G  GL+GPPG+ G               KG+KG PGLPGL    G QG 
Sbjct: 129  TQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGA 188

Query: 587  PGFAGNIGSPGYPGRQGLAGPEGNPGP-----------KGAQGFIGSPGEA--------- 626
            PGF G +G  G PG QG  GP G  GP           KG +G +G PG A         
Sbjct: 189  PGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGEL 248

Query: 627  ----------GQLGPEGERGIPGIRGKKGF-----------KGRQGFPGDFGDRGP---A 662
                      G  G  G +G PGI G  GF           KG +G PG  G RGP    
Sbjct: 249  EFMGFPKGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSE 308

Query: 663  GLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGP--------MGLSGN------KG 708
            G+ G PG  G  G  GFPGL G  G  G  G  G+PGP          +SGN       G
Sbjct: 309  GVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPG 368

Query: 709  LPGIKGDKGEQGTAGELGEPGYP---GDKGAVGLPGPPGMRGKSGPSGQT-----GDPGL 760
            LPG+KGD+G QG  G  G PG P   G  GA+G  G PG++G  G  G+T     G PG 
Sbjct: 369  LPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGR 428

Query: 761  QGPSGPPGPEGFPG-----------DIGIPGQNGPEGPKGLLGNR--------------- 794
             G  GPPGP G P            + G PG  G +GPKG LG +               
Sbjct: 429  DGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGV 488

Query: 795  ---------GPPGP------PGLKGTQGE------EGPIGAFGELGPRGKPGQKGYAGEP 833
                     GPPGP      PGLKG +G+      +GP GA G +GP G  G KG  GEP
Sbjct: 489  PNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEP 548

Query: 834  ------GPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEK 887
                  G  G +G+ G QG  G IGE G  G+PG  G+ G  G+ G+ G PG  G  G  
Sbjct: 549  ILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQ-GFPGEKGLPGLP 607

Query: 888  GVMGYPGPPGVPGP-----IGPLGLPGHVGARGPPGSQGPKGQR---------GSRGPDG 933
            G  G+PGPPG+PG       GP GLPG  G  G PG QG  G +         GS GP G
Sbjct: 608  GEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSG 667

Query: 934  LLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPG 993
              G  G  G KG +G  G  G  G  G  G PG  G    P L G PG  G++GLPG PG
Sbjct: 668  FPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPG 727

Query: 994  L------------------RGLQGDV-----GPPGEMGMEGPPGTEGESGLQGEPGAKGD 1030
            L                  +G  GD+     G PGE G++G  G +G  G  G PG KG 
Sbjct: 728  LPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGV 787

Query: 1031 VGTAGSVGGTGE------PGLRGEPGAPGEE---GLQGKDGLKGVPGGRGL---PGEDGE 1078
             G  G +G  GE      PG  G+PG PG     G++GK GL G PG  G+   PG+ G 
Sbjct: 788  HGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGT 847

Query: 1079 KGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGE---VGSRGP 1135
            +G+ G PG I   G  G  GLPG  G+VG+ G  G PG  G     GP GE   VG  G 
Sbjct: 848  RGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGF 907

Query: 1136 PGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPK-------- 1187
            PG  G  G  G RG +G  G  G MGP G  G PG +G +G PGP G+P P+        
Sbjct: 908  PGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWL 967

Query: 1188 ----------GEKGYPGE--DSTVLGPPGP----------------RGEPGPVGDQGERG 1219
                      G  G+PG   D    G PGP                 G+PGP G  G RG
Sbjct: 968  KGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRG 1027

Query: 1220 EPGAEGYKGHVGVPGLRGATGQQ----------------------------GPPGEPGDQ 1251
             PG +G  G  G PG+ G +G Q                            G PG  G  
Sbjct: 1028 LPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQP 1087

Query: 1252 GEQGLKGERGSEG---------NKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGIS 1302
            GE G KG +G +G         NKG+ G  G SG  G+PG  G  G  G++G  G  G S
Sbjct: 1088 GESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSS 1147

Query: 1303 GNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGS--------SGLPGSPGIQGPKG 1354
            G+ G IGP G  GL G +G PG  GL G  G PG KG+        +G+PG  G+ GPKG
Sbjct: 1148 GHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKG 1207

Query: 1355 EQ-------GLPGQPGIQGKRGHRGAQGDQGPCGDPG---------LKGQPGEYGVQGLT 1398
            E+       G PG+PG++G++G RG  G QGP G PG         + GQPG+ G  GL 
Sbjct: 1208 EKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLD 1267

Query: 1399 GFQGFPGPKGP------------EGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRT 1446
            G +G PGP GP             GD G  GI GPKGP   +G+ G  G  G+ G  G  
Sbjct: 1268 GERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGP---KGDQGIPGFSGLPGELGLK 1324

Query: 1447 GPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPR 1479
            G RGE GF G  G  GP G PG PG  G  GPR
Sbjct: 1325 GMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPR 1357



 Score =  726 bits (1875), Expect = 0.0
 Identities = 493/1241 (39%), Positives = 582/1241 (46%), Gaps = 263/1241 (21%)

Query: 489  GPKGDTGP------------------PGPPGPAGIPGPSGKRGPRGIPGPHGNPGL---P 527
            GPKGD GP                  PGP GP G+ G +G +G  G PGP G PGL   P
Sbjct: 89   GPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPP 148

Query: 528  GLPGPKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIP 587
            GLPG KG KGDP  +PG    G KGD GL GL G  G QG  G  G  G  G PG QG P
Sbjct: 149  GLPGQKGSKGDPVLAPGS-FKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPP 207

Query: 588  GFAGNIGSPG-----YPGRQGLAGPEGNPGP----------------KGAQGFIGSPGEA 626
            G  G +G  G     + G +G+ G  G PGP                KG +G  G PG  
Sbjct: 208  GPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPK 267

Query: 627  GQLGPEGERGIPGI--RGKKGFKGRQGFPGDFGDRGPAG---LDGSPGLVGGTGPPGFPG 681
            G  G  G  G PG+   G+KG KG +G PG  G RGP G   + G PG  G  G  GFPG
Sbjct: 268  GFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPG 327

Query: 682  LRGSVGPVGPIGPAGIPGP--------MGLSGNKG------LPGIKGDKGEQGTAGELGE 727
            L G  G  G  G  G+PGP          +SGN G      LPG+KGD+G QG  G  G 
Sbjct: 328  LNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGV 387

Query: 728  PGYP---GDKGAVGLPGPPGMRGKSGPSGQT-----GDPGLQGPSGPPGPEGFPG----- 774
            PG P   G  GA+G  G PG++G  G  G+T     G PG  G  GPPGP G P      
Sbjct: 388  PGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFET 447

Query: 775  ------DIGIPGQNGPEGPKGLLGNRG------------------------PPGP----- 799
                  + G PG  G +GPKG LG +G                        PPGP     
Sbjct: 448  ETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIG 507

Query: 800  -PGLKGTQGE------EGPIGAFGELGPRGKPGQKGYAGEP------GPEGLKGEVGDQG 846
             PGLKG +G+      +GP GA G +GP G  G KG  GEP      G  G +G+ G QG
Sbjct: 508  LPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQG 567

Query: 847  NIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLG 906
              G IGE G  G+PG  G+ G  G+ G+ G PG  G  G  G  G+PGPPG+PG      
Sbjct: 568  FRGVIGEPGKDGVPGLPGLPGLPGDGGQ-GFPGEKGLPGLPGEKGHPGPPGLPG------ 620

Query: 907  LPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGD---QGKRGPHGLIGKTG 963
                    G PG  GP+G  G +G DGL G+QG+ G+KG        G  GP G  G  G
Sbjct: 621  -------NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPG 673

Query: 964  NPGERGFQGKPGLQGLPGSTGDRGLPGEPGL------------RGLQGDVGPPGEMGMEG 1011
             PG +G +G PG  G PGS+G +G PG PGL            RG +G  G PG  G +G
Sbjct: 674  FPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDG 733

Query: 1012 PPGTEGESGLQGEPGAKGDV--------GTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGL 1063
             PG  G  GL G  GA GD+        G  G  G TG  G  G+ G PG +G+ GK GL
Sbjct: 734  LPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGL 793

Query: 1064 KGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQ 1123
             G  G RG PG  G+ G+ G PG  GP G  G++GLPG  G    PG  G PGKKG +G+
Sbjct: 794  LGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGF---PGISGHPGKKGTRGK 850

Query: 1124 IGPTGEV---------------------GSRGPPGKIGKSGPKGARGTRGAVGHLGLMGP 1162
             GP G +                     GS G PG  G     G +G +G+VG +G  G 
Sbjct: 851  KGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGI 910

Query: 1163 DGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGE--------------------------D 1196
             G PGIPG RG +G PG +G  GP G  G PGE                          D
Sbjct: 911  PGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGD 970

Query: 1197 STVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGL-RGATGQQGPPGEPGDQGEQG 1255
                G  G  G PGP GD+GE G PG  G  G  G+PG+ +G +G+ GPPG  G +G  G
Sbjct: 971  KGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPG 1030

Query: 1256 LKG------------ERGSEGNKGKKGAPGPSGKPGI-------------PGLQGLLGPK 1290
            LKG            E GS+G +G  G PG SG PG+             PG +G  G  
Sbjct: 1031 LKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGES 1090

Query: 1291 GIQGYHGADGISGN---------PGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSS 1341
            G +G  G DG+ GN          GK+G  G  GLPG  G PG  G+ G PG PG  G  
Sbjct: 1091 GFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQ 1150

Query: 1342 GLPG---SPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPC-----GDPGLKGQPGEYG 1393
            G  G   SPG+ GPKG  G PG  G+ G  G +G  G  GP      G  GL G  GE G
Sbjct: 1151 GAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKG 1210

Query: 1394 VQGL-TGFQGFPGPKGPEGDAGIVGISGPKGPIGH---------RGNTGPLGREGIIGPT 1443
              G+  G  G PG +G +GD G  G+ GP G  G           G  G  GR G+ G  
Sbjct: 1211 YPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGER 1270

Query: 1444 GRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQMDI 1484
            GR GP G  G  G +  QG  G PG PG PG  GP+    I
Sbjct: 1271 GRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGI 1311



 Score =  725 bits (1871), Expect = 0.0
 Identities = 449/1041 (43%), Positives = 538/1041 (51%), Gaps = 111/1041 (10%)

Query: 489  GPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGP------KGDPGFS 542
            GP G+ GPPGP G  G+PG  G RG RG  G  G  G PGL GP GP      KG+P  S
Sbjct: 492  GPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILS 551

Query: 543  PGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQ 602
              Q +PG++GD G  G  G  G  G  G+ G PGLPGLPG+       G  G PG  G  
Sbjct: 552  TIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGD-------GGQGFPGEKGLP 604

Query: 603  GLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPA 662
            GL G +G+PGP G  G        G  G  G RG+PG +GK G  G+QG PG  G   P 
Sbjct: 605  GLPGEKGHPGPPGLPG-------NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPC 657

Query: 663  GLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTA 722
             + GS G  G  G PGFPG +GS                GL G  G PG  G KGE G+ 
Sbjct: 658  IIPGSYGPSGFPGTPGFPGPKGS---------------RGLPGTPGQPGSSGSKGEPGSP 702

Query: 723  G--ELGE-PGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIP 779
            G   L E PG+PG +G  GLPG PG+ GK G  G  G PGL G  G  G + F  + G P
Sbjct: 703  GLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATG-DIFGAENGAP 761

Query: 780  GQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLK 839
            G+ G +G  G  G  G  G PGLKG  G+ G +G  GE G  G PGQ G  G PG     
Sbjct: 762  GEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPG----- 816

Query: 840  GEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVP 899
                  G  G  G++G  G PG  G++G  G+KG RG  GP G   +KG+ G  G PG P
Sbjct: 817  ----SSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNP 872

Query: 900  GPIGPLGLPGHVGARGPPGSQGPKGQRGSRGP---DGLLGEQGIQGAKGEKGDQGKRGPH 956
            G +G  G PG  G  G P   GPKG++GS G     G+ G  GI G +G KG  G  G  
Sbjct: 873  GLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKM 932

Query: 957  GLIGKTGNPGERGFQGKPGLQGLP---------------GSTGDRGLPGEPGLRGLQGDV 1001
            G  G+ G PGE+G +G PG  G+P               GS G  G  G PG RG +G+ 
Sbjct: 933  GPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEA 992

Query: 1002 GPPGEMGMEGPPGTEGE-SGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGK 1060
            G PG  G+ G PG  G   G+ G+PG  G +G  G  G  G  G+ G PG PGE G QG 
Sbjct: 993  GRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGI 1052

Query: 1061 DGLKGVPGGRGLPGEDGEKGE-MGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKG 1119
             G  G+PG  GLPG  G+ G+ + + G  GP G+ G++G  G +G  G+ G  G PG KG
Sbjct: 1053 RGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKG 1112

Query: 1120 DKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPG 1179
            + G++G +G+VG  G PG  G +G +G  G  G+ GH G +GP G PG+ G +G  G PG
Sbjct: 1113 EDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPG 1172

Query: 1180 P---SGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQG-------ERGEPGAEGYKGH 1229
                +GLPG KG  G PG   T  G PGP G PGP G++G         G+PG  G KG 
Sbjct: 1173 LHGLNGLPGTKGTHGTPGPSIT--GVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGD 1230

Query: 1230 VGVPGLRGATGQQGPPG---------EPGDQGEQGLKGERGSEGNKGKKGAPGPS---GK 1277
             G PGL+G  G  G PG         +PGD G  GL GERG  G  G  G PGPS   G 
Sbjct: 1231 RGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGD 1290

Query: 1278 PGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGV 1337
             G PG  G+ GPKG +G  G  G SG PG++G  G +G PG  G PG+ G  G PG PG+
Sbjct: 1291 TGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGM 1350

Query: 1338 K------GSSGLPGSPG-------IQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPG 1384
            K      GSSGL G PG       +Q P G  GLPG  GI G  G  GAQG  G  G  G
Sbjct: 1351 KGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKG 1410

Query: 1385 LKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTG 1444
            L G PG+ G  GL      PGP G  GD G+ G+ GP G  G  G  GP G  G+ G + 
Sbjct: 1411 LPGIPGKDGPSGL------PGPPGALGDPGLPGLQGPPGFEGAPGQQGPFGMPGMPGQSM 1464

Query: 1445 RTGPRGEKGFRGETGPQGPRG 1465
            R G    K  + E  P  P G
Sbjct: 1465 RVGYTLVKHSQSEQVPPCPIG 1485



 Score =  701 bits (1808), Expect = 0.0
 Identities = 468/1171 (39%), Positives = 548/1171 (46%), Gaps = 221/1171 (18%)

Query: 519  GPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLP 578
            G  G PG  G+ GP GP+G   F+    + G KG++G  GL+GP G +GDKG  G PG  
Sbjct: 47   GARGRPGPIGIQGPTGPQG---FTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFL 103

Query: 579  GLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGI- 637
            G+ G  G PG  G  G PG  G  G  G  G PGP G  G +G PG  GQ G +G+  + 
Sbjct: 104  GINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLA 163

Query: 638  PGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGI 697
            PG    KG KG  G PG  G  GP G  G PG VG  GPPG  G  G  GP+GP G  G+
Sbjct: 164  PG--SFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGL 221

Query: 698  --PGPMGLSGNKGLPGIKG-------------DKGEQGTAGELGEPGYPGDKGAVGLPGP 742
               G  G+ G+ GLPG  G              KG++G+ GE G  G+PG  G  G PG 
Sbjct: 222  GFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFPG- 280

Query: 743  PGMRGKSGPSGQTGDPGLQGP---------SGPPGPEGFPGDIGIPGQNGPEGPKG---- 789
             G  G+ G  G+ G PGL GP          GPPG +G  G +G PG NG +G +G    
Sbjct: 281  LGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGD 340

Query: 790  ----------------LLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEP 833
                            + GN G PG PGL G +G+EG  G  G  G  G P   G  G  
Sbjct: 341  IGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGAL 400

Query: 834  GPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKG--------------ERGSPG 879
            GP+G  G  GDQGN G+    G  GLPG  G+ G  G  G              E G PG
Sbjct: 401  GPQGFPGLKGDQGNPGRT-TIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPG 459

Query: 880  PLGPQGEKGVMGY---------------------PGPPGVPGPIGPLGLPGHVGARGPPG 918
              G QG KG +G                      PG PG PGP G +GLPG  GARG  G
Sbjct: 460  LRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRG 519

Query: 919  S---QGPKGQRGSRGPDGLLGEQG---------IQGAKGEKGDQGKRGPHGLIGKTGN-- 964
            S   QGP G  G  GP G  G +G         IQG  G++GD G +G  G+IG+ G   
Sbjct: 520  SGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDG 579

Query: 965  ---------------------------PGERGFQGKPGL--QGLPGSTGDRGLPGEPGLR 995
                                       PGE+G  G PGL   GLPG  G RGLPG+ G  
Sbjct: 580  VPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKD 639

Query: 996  GLQGDVGPPGEMGM---------------EGPPGTEGESGLQGEPGAKGDVGTAGSVGGT 1040
            GL G  G PG  G+                G PG  G  G +G PG  G  G++GS G  
Sbjct: 640  GLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEP 699

Query: 1041 GEPGL------------RGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKG-----EMG 1083
            G PGL            RGE G PG  GL GKDGL G+ G  GLPG  G  G     E G
Sbjct: 700  GSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENG 759

Query: 1084 LPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSG 1143
             PG  G  G +G  G  G  G+ G+ G  G+PG  G KG+ G  G  G  G PG  G SG
Sbjct: 760  APGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSG 819

Query: 1144 PKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPG---PSGLPGPKGEKGYPGEDSTVL 1200
            P G +G  G  G  G  G  G PG  G RG +G PG     GLPG KG  G PG    ++
Sbjct: 820  PYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPG----LV 875

Query: 1201 GPPGPRGEPGPVG---DQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLK 1257
            G  G  G PG  G     G +GE G+ G+ G  G+PGL G  G +G  G PG  G+ G  
Sbjct: 876  GLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPS 935

Query: 1258 GERGSEGNKGKKGAPGPSGKP------------GIPGLQGLLGPKGIQGYHGADGISGNP 1305
            G  G+ G KG +G PGP G P            G  G QG  G  G  G  G  G +G P
Sbjct: 936  GRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRP 995

Query: 1306 GKIGPPGKQGLPGI----RGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQ 1361
            G  G PG  GLPGI     G PG  G  G  G PG+KGSSG+ G PG+ G  G QG+ G 
Sbjct: 996  GPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGS 1055

Query: 1362 PGIQGKRGHRGAQGDQGP----CGDPGLKGQPGEYGVQ------GLTGFQGFPGPKGPEG 1411
            PG+ G  G  G +GD G      G PG KGQPGE G +      GL G  GFPG KG +G
Sbjct: 1056 PGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDG 1115

Query: 1412 DAGI---VGISGP---------------KGPIGHRGNTGPLGREGIIGPTGRTGPRGEKG 1453
              G+   VG+ G                 G  GH+G  GPLG  G+IGP G  G  G  G
Sbjct: 1116 KVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHG 1175

Query: 1454 FRGETGPQGPRGQPGP-----PGPPGAPGPR 1479
              G  G +G  G PGP     PGP G PGP+
Sbjct: 1176 LNGLPGTKGTHGTPGPSITGVPGPAGLPGPK 1206



 Score =  607 bits (1564), Expect = e-173
 Identities = 395/930 (42%), Positives = 459/930 (49%), Gaps = 102/930 (10%)

Query: 643  KKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMG 702
            +KG +GR G  G  G  GP G  GS GL G  G  GFPGL G  GP G  GP G+PG +G
Sbjct: 45   EKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLG 104

Query: 703  LS---GNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGP-------- 751
            ++   G+ G PG +G  G  G  G  G  G+PG  G  GL GPPG+ G+ G         
Sbjct: 105  INGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAP 164

Query: 752  ---SGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGT--- 805
                G  GDPGL G  G  GP+G P   G PG  GP GP GL G  GPPGP G  G    
Sbjct: 165  GSFKGMKGDPGLPGLDGITGPQGAP---GFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGL 221

Query: 806  --QGEEGPIGAFGELGPRGKPGQKGYAGEPG-PEGLKGEVGDQGNIGKIGETGPVGLPGE 862
              QGE+G  G  G  GP G P   G     G P+G KG  G+ G  G  G +GP G PG 
Sbjct: 222  GFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFPG- 280

Query: 863  VGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGP 922
            +G TG  GEKGE+G PG  GP+G  G  G  GPPG  G  G LG P   G  G  G +G 
Sbjct: 281  LGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFP---GLNGFQGIEGQ 337

Query: 923  KGQRGSRGPD--------------GLLGEQGIQGAKGEKGDQGKRGPHGLIG---KTGNP 965
            KG  G  GPD              G  G  G+ G KG++G QG RGP G+ G    +G P
Sbjct: 338  KGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVP 397

Query: 966  GERGFQGKPGL---QGLPGST--GDRGLPGEPGLRGLQGDVGPPG-----------EMGM 1009
            G  G QG PGL   QG PG T  G  GLPG  GL G  G  GPP            E G 
Sbjct: 398  GALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGF 457

Query: 1010 EGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGG 1069
             G  G +G  G  G  G KGD G     GG    G  GEPG PG  GL G  GLKG  G 
Sbjct: 458  PGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGD 517

Query: 1070 RGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGE 1129
            RG  G  G  G  GL G +GP G  G+ G P    I G+PG RG  G +G +G IG  G+
Sbjct: 518  RGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGK 577

Query: 1130 VGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGH--QGQPGPSGLPGPK 1187
             G  G PG  G  G  G +G  G  G  GL G  G PG PG  G+   G PGP GLPG K
Sbjct: 578  DGVPGLPGLPGLPG-DGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGDK 636

Query: 1188 GEKGYPGEDSTVLGPPGPR---------GEPGPVGDQGERGEPGAEGYKGHVGVPGLRGA 1238
            G+ G PG+     G PG +         G  GP G  G  G PG +G +G  G PG  G+
Sbjct: 637  GKDGLPGQQ----GLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGS 692

Query: 1239 TGQQGPPGE---------PGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLG- 1288
            +G +G PG          PG  G +G KG  G  G  GK G PG  G PG+PG +G  G 
Sbjct: 693  SGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGD 752

Query: 1289 ----PKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLP 1344
                  G  G  G  G++G+ G +G  G  GL G+ G PG  G  G  G PG  G  G P
Sbjct: 753  IFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQP 812

Query: 1345 GSPGIQGP---KGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQ 1401
            G+PG  GP   KG+ GLPG PG  G  GH G +G +G  G PG   + G  G++GL G  
Sbjct: 813  GTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNP 872

Query: 1402 GFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQ 1461
            G  G KG  G  G+ G+    GP G +G+ G +G  GI G  G  G RG KG  G TG  
Sbjct: 873  GLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKM 932

Query: 1462 GP---------RGQPGPPGPPGAPGPRKQM 1482
            GP         +G  G PGP G P PR+ M
Sbjct: 933  GPSGRAGTPGEKGDRGNPGPVGIPSPRRPM 962



 Score =  489 bits (1260), Expect = e-138
 Identities = 326/832 (39%), Positives = 398/832 (47%), Gaps = 167/832 (20%)

Query: 804  GTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPE---------GLKGEVGDQGNIGKI--- 851
            G Q   G    F E G RG+PG  G  G  GP+         GLKGE G  G +G     
Sbjct: 32   GGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPK 91

Query: 852  GETGPVGLPGEVGMT---GSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLP 908
            G+ GP+G+PG +G+    G  G+ G RG PG  G  G +G +G+PGP G PG +GP GLP
Sbjct: 92   GDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLP 151

Query: 909  GH-----------------------------------------VGARGPPGSQGPKGQRG 927
            G                                          VG  GPPG QGP G  G
Sbjct: 152  GQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPG 211

Query: 928  SRGPDGLLGEQGIQGAKGEKGDQGKRGPHG-------------LIGKTGNPGERGFQGKP 974
              GPDG +G  G QG KG KGD G  GP G               GK G+ GE G +G P
Sbjct: 212  PLGPDGNMG-LGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFP 270

Query: 975  GLQGLP-----GSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGE---------SG 1020
            G+ G P     G+TG++G  GE G+ GL G  GP G  G++GPPG +G+         +G
Sbjct: 271  GISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNG 330

Query: 1021 LQGEPGAKGDVGTAGS-----------VGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGG 1069
             QG  G KGD+G  G             G  G+PG+ G PG  G+EG+QG  G  GVPG 
Sbjct: 331  FQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGL 390

Query: 1070 RGLPGEDGEKGEMGLPGIIGPLGRSGQT-----GLPGPEGIVGIPGQRGRPGKKGD---- 1120
              L G  G  G  G PG+ G  G  G+T     GLPG +G+ G PG  G P  + +    
Sbjct: 391  PALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETL 450

Query: 1121 -KGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEP---------GIPG 1170
               + G  G  G +GP G +G  G KG  G     G +   GP GEP         G+PG
Sbjct: 451  HNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPG 510

Query: 1171 YRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPG-PV-----GDQGERGEPGAE 1224
             +G +G  G  G  GP G  G  G     LGP GP+G+ G P+     G  G+RG+ G++
Sbjct: 511  LKGARGDRGSGGAQGPAGAPGLVGP----LGPSGPKGKKGEPILSTIQGMPGDRGDSGSQ 566

Query: 1225 GYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQ 1284
            G++G +G PG  G  G  G PG PGD G QG  GE+G  G  G+KG PGP G PG  GL 
Sbjct: 567  GFRGVIGEPGKDGVPGLPGLPGLPGD-GGQGFPGEKGLPGLPGEKGHPGPPGLPG-NGLP 624

Query: 1285 GLLGPKGIQGYHGADGISGN---------------PGKIGPPGKQGLPGIRGGPGRTGLA 1329
            GL GP+G+ G  G DG+ G                PG  GP G  G PG  G  G  GL 
Sbjct: 625  GLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLP 684

Query: 1330 GAPGPPGVKGSSGLPGSPGI---------QGPKGEQGLPGQPGIQGKRGHRGAQGDQGPC 1380
            G PG PG  GS G PGSPG+          GP+GE+GLPG PG+ GK G  G  G  G  
Sbjct: 685  GTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLP 744

Query: 1381 GDPGL--------KGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTG 1432
            G  G          G PGE G+QGLTG +GF G  G  G  G+ G  G  GP G RG+ G
Sbjct: 745  GSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPG 804

Query: 1433 PLGREGIIGPTGRTGPRGEK---------GFRGETGPQGPRGQPGPPGPPGA 1475
              G+ G  G  G +GP G K         GF G +G  G +G  G  GPPG+
Sbjct: 805  TPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGS 856



 Score =  437 bits (1123), Expect = e-122
 Identities = 288/736 (39%), Positives = 339/736 (46%), Gaps = 124/736 (16%)

Query: 865  MTGSIGEKGERGSPGPLGPQG---------EKGVMGYPGPPGVPGPIGP------LGLPG 909
            +T  +   GE+    P G Q          EKG  G PGP G+ GP GP       GL G
Sbjct: 15   LTEELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSG 74

Query: 910  HVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERG 969
              G RG PG  GP G +G +GP G+ G  GI G  G  G  G RGP GL G  G  G  G
Sbjct: 75   LKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVG 134

Query: 970  FQGKPGLQGLPGSTGDRGLP--------------------GEPGLRGLQGDVGP------ 1003
            F   PG  G PG  G  GLP                    G+PGL GL G  GP      
Sbjct: 135  F---PGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGF 191

Query: 1004 PGEMGMEGPPGTEGES--------------GLQGEPGAKGDVGTAGSVG---GTGEPGLR 1046
            PG +G  GPPG +G                G QGE G KGDVG  G  G    TGE    
Sbjct: 192  PGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFM 251

Query: 1047 GEP----GAPGEEGLQGKDGLKGVPG--GRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLP 1100
            G P    G+ GE G +G  G+ G PG  G G  GE GEKGE G+PG+ GP G  G  G+ 
Sbjct: 252  GFPKGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQ 311

Query: 1101 GPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGP-----------PGKIGKSGPKGARG 1149
            GP G  G  G  G PG  G +G  G  G++G  GP            G  G  G  G  G
Sbjct: 312  GPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPG 371

Query: 1150 TRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDST----------V 1199
             +G  G  GL GP G PG+P   G  G  GP G PG KG++G PG  +           +
Sbjct: 372  LKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGL 431

Query: 1200 LGPPGPRGEPGPV-----------------GDQGERGEPGAEGYKGHVGVPGLRGATGQQ 1242
             GPPGP G P P                  G+QG +G  G +G KG  G     G     
Sbjct: 432  PGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNT 491

Query: 1243 GPPGEPGDQGEQ---GLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGAD 1299
            GPPGEPG  G     GL G +G+ G++G  GA GP+G PG+ G  G  GPKG +G     
Sbjct: 492  GPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILS 551

Query: 1300 GISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGV--KGSSGLPGSPGIQGPKGEQG 1357
             I G PG  G  G QG  G+ G PG+ G+ G PG PG+   G  G PG  G+ G  GE+G
Sbjct: 552  TIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKG 611

Query: 1358 LPGQPGIQGK-----RGHRGAQGDQGPCGDPGLKGQPGEYGV---------QGLTGFQGF 1403
             PG PG+ G       G RG  GD+G  G PG +G PG  G+          G +GF G 
Sbjct: 612  HPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGT 671

Query: 1404 PGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGP 1463
            PG  GP+G  G+ G  G  G  G +G  G  G   +    G  GPRGEKG  G  G  G 
Sbjct: 672  PGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGK 731

Query: 1464 RGQPGPPGPPGAPGPR 1479
             G PG  G PG PG +
Sbjct: 732  DGLPGMIGSPGLPGSK 747



 Score =  390 bits (1002), Expect = e-108
 Identities = 262/685 (38%), Positives = 322/685 (47%), Gaps = 111/685 (16%)

Query: 905  LGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGN 964
            L L   + A G      P G +   G      E+G +G  G  G QG  GP G  G TG 
Sbjct: 13   LCLTEELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGL 72

Query: 965  PGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGE 1024
             G +G +G PGL G  G  GD+G  G PG  G+ G  G PG+ G  GPPG +G +G QG 
Sbjct: 73   SGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGA 132

Query: 1025 ---------PGAKGDVGTAGSVGGTGEP--------GLRGEPGAPGEEGLQGKDGLKGVP 1067
                     PG  G  G  G  G  G+P        G++G+PG PG +G+ G  G  G P
Sbjct: 133  VGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFP 192

Query: 1068 GGRGLPGEDGEKGEMGLPGIIGPLGRSGQ--TGLPGPEGIVGIPGQRGRP---------- 1115
            G  G  G  G +G  G PG +GP G  G    G  G +G VG+PG  G P          
Sbjct: 193  GAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMG 252

Query: 1116 ---GKKGDKGQIGPTGEVGSRGPPG--KIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPG 1170
               GKKG KG+ GP G  G  GPPG   +G +G KG +G +G  G  G  GP G  G+ G
Sbjct: 253  FPKGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQG 312

Query: 1171 YRGHQGQPGPSGLP---------GPKGEKGYPGED-------STVLGPPGPRGEPGPVGD 1214
              G QG+ G  G P         G KG+ G PG D       + + G PG  G PG  G 
Sbjct: 313  PPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGL 372

Query: 1215 QGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGER--GSEGNKGKKGAP 1272
            +G+ G  G  G  G  G+P L G  G  GP G PG +G+QG  G    G+ G  G+ G P
Sbjct: 373  KGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLP 432

Query: 1273 GPSGKP-----------------GIPGLQGLLGPKGIQGYHGADGIS------------G 1303
            GP G P                 G PGL+G  GPKG  G  G  G S            G
Sbjct: 433  GPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTG 492

Query: 1304 NPGKIGPPGKQ---GLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGE----- 1355
             PG+ GPPG     GLPG++G  G  G  GA GP G  G  G  G  G +G KGE     
Sbjct: 493  PPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILST 552

Query: 1356 -QGLPGQPGIQGKRGHRGAQGDQGPCGDPGL-----------KGQPGEYGVQGLTGFQGF 1403
             QG+PG  G  G +G RG  G+ G  G PGL           +G PGE G+ GL G +G 
Sbjct: 553  IQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGH 612

Query: 1404 PGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRT---------GPRGEKGF 1454
            PGP G  G+ G+ G+ GP+G  G +G  G  G++G+ G  G T         GP G  G 
Sbjct: 613  PGPPGLPGN-GLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGT 671

Query: 1455 RGETGPQGPRGQPGPPGPPGAPGPR 1479
             G  GP+G RG PG PG PG+ G +
Sbjct: 672  PGFPGPKGSRGLPGTPGQPGSSGSK 696



 Score =  376 bits (966), Expect = e-104
 Identities = 243/600 (40%), Positives = 292/600 (48%), Gaps = 87/600 (14%)

Query: 488  RGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGN---PGLPGLPGPKGPKGDPGF--- 541
            +G KG  G  G PG  G+PG  G RG +GIPG  G     G  G PG KG +G+PG    
Sbjct: 896  KGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGI 955

Query: 542  -SPGQPVP-----GEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNI-G 594
             SP +P+      G+KG QG +G  G PG +GDKG  G PG PGLPG  G+PG    + G
Sbjct: 956  PSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSG 1015

Query: 595  SPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQG--- 651
             PG PG  G+ G  G  G  G  GF G PGE+G  G  G  G+PG  G  G KG  G   
Sbjct: 1016 KPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTV 1075

Query: 652  ----FPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMG---LS 704
                 PG  G  G +G  G+ G  G  G  GFPG +G  G VG  G  G+PG  G   ++
Sbjct: 1076 EISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVA 1135

Query: 705  GNKGLPGIKGDKGEQGTAGELGEPGY------------------PGDKGAVGLPGP---- 742
            G +G PG+ G  G QG  G LG PG                   PG KG  G PGP    
Sbjct: 1136 GMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITG 1195

Query: 743  -PGMRGKSGPSGQTGDPGLQ-GPSGPPGPEGFPGDIGIPGQNGPEG---------PKGLL 791
             PG  G  GP G+ G PG+  G  G PG  G  GD G PG  GP G         P  + 
Sbjct: 1196 VPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIA 1255

Query: 792  GNRGPPGPPGLKGTQGEEGPIGAFGELGP---RGKPGQKGYAGEPGPEGLKGEVGDQGNI 848
            G  G PG PGL G +G  GP G  G  GP   +G  G  G+ G PGP+G KG+ G  G  
Sbjct: 1256 GQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFS 1315

Query: 849  GKIGETGPVGL---PGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPG-------V 898
            G  GE G  G+   PG +G  G +G  G+ G PG  G  G +G  G  G PG       V
Sbjct: 1316 GLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAV 1375

Query: 899  PGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGL 958
              P GPLGLP      G  G  G  G  G++GP GL G +G+ G  G+ G  G  GP G 
Sbjct: 1376 QVPPGPLGLP------GIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGA 1429

Query: 959  IGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPG---------LRGLQGDVGPPGEMGM 1009
            +   G+PG  G QG PG +G PG  G  G+PG PG         ++  Q +  PP  +GM
Sbjct: 1430 L---GDPGLPGLQGPPGFEGAPGQQGPFGMPGMPGQSMRVGYTLVKHSQSEQVPPCPIGM 1486



 Score =  188 bits (477), Expect = 4e-47
 Identities = 122/277 (44%), Positives = 142/277 (51%), Gaps = 27/277 (9%)

Query: 487  LRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGL------PGPKGPKGDPG 540
            LRG KGD G PG  GPAG+PG  G   P  I G  G+PG PGL      PGP GP G PG
Sbjct: 1224 LRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPG 1283

Query: 541  FSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPG---LPGEQGIPGFAGNIGSPG 597
             S  Q   G+ GD G  G+ GP G +GD+G+ G  GLPG   L G +G PGF G  G  G
Sbjct: 1284 PSSNQ---GDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVG 1340

Query: 598  YPGRQGLAGPEGNPGPKGAQGFIGSPG-----EAGQLGPEGERGIPGIRGKKGFKGRQGF 652
             PG  G  G +G  GP+G+ G  G PG     EA Q+ P G  G+PGI       G  G 
Sbjct: 1341 PPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQV-PPGPLGLPGI------DGIPGL 1393

Query: 653  PGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGI 712
             GD G +GP GL GS GL    G PG  G  G  GP G +G  G+PG  G  G +G PG 
Sbjct: 1394 TGDPGAQGPVGLQGSKGL---PGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPGQ 1450

Query: 713  KGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKS 749
            +G  G  G  G+    GY   K +     PP   G S
Sbjct: 1451 QGPFGMPGMPGQSMRVGYTLVKHSQSEQVPPCPIGMS 1487


>gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo
            sapiens]
          Length = 1690

 Score =  734 bits (1895), Expect = 0.0
 Identities = 469/1130 (41%), Positives = 558/1130 (49%), Gaps = 170/1130 (15%)

Query: 488  RGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGN---PGLPGLPGPKGPKGDPGF--- 541
            +G KG+ G PG PGP G  G  G +GP G  G  G    PGL G  G +G KGD G    
Sbjct: 286  KGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGP 345

Query: 542  -------------SPGQP----VPGEKGDQGLSGLMGPPGMQGDKGLKGHPG------LP 578
                         +PG P    +PG KGD+G+ GL GP G+ G   L G PG       P
Sbjct: 346  DVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFP 405

Query: 579  GLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFI--------GSPGEAGQLG 630
            GL G+QG PG    IG+ G PGR GL GP G PGP   +           G PG  G+ G
Sbjct: 406  GLKGDQGNPGRT-TIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQG 464

Query: 631  PEGERGIPGIRGKKGFKG------RQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRG 684
            P+G  G+ GI+G  GF          G PG+ G  GP GL G PGL G  G  G  G +G
Sbjct: 465  PKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQG 524

Query: 685  SVGPVGPIGPAGIPGPMGLSGN------KGLPGIKGDKGEQGTAGELGEPGYPGDKGAVG 738
              G  G +GP G  GP G  G       +G+PG +GD G QG  G +GEPG  G  G  G
Sbjct: 525  PAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPG 584

Query: 739  LPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPG 798
            LPG PG  G+  P G+ G PGL G  G PGP G PG+ G+PG  GP G  G  G  G PG
Sbjct: 585  LPGLPGDGGQGFP-GEKGLPGLPGEKGHPGPPGLPGN-GLPGLPGPRGLPGDKGKDGLPG 642

Query: 799  PPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVG 858
              GL G++G   P    G  GP G PG  G+   PGP+G +G                  
Sbjct: 643  QQGLPGSKGITLPCIIPGSYGPSGFPGTPGF---PGPKGSRG------------------ 681

Query: 859  LPGEVGMTGSIGEKGERGSPGPL---------GPQGEKGVMGYPGPPG---VPGPIGPLG 906
            LPG  G  GS G KGE GSPG +         GP+GEKG+ G+PG PG   +PG IG  G
Sbjct: 682  LPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPG 741

Query: 907  LPGHVGARGP-----PGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGK 961
            LPG  GA G       G+ G +G +G  G  G LG+ G+ G KG  G  G  GP G  G 
Sbjct: 742  LPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGS 801

Query: 962  TGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGL 1021
             G PG+ G  G PG  G  G  G  GLPG PG  G+ G  G  G  G +GPPG+  + GL
Sbjct: 802  PGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGL 861

Query: 1022 QGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGE 1081
             G  G  G+ G  G  G  G PG+ G P   G +G +G  G  G PG  GLPG  G +G 
Sbjct: 862  PGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGL 921

Query: 1082 MGLPGIIGPLGRSGQTGLPGPEGI------VGIP---------------------GQRGR 1114
             G+PG  G +G SG+ G PG +G       VGIP                     G  G 
Sbjct: 922  KGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGF 981

Query: 1115 PGKKGDKGQIG---PTGEVGSRGPPGKI----GKSGPKGARGTRGAVGHLGLMGPDGEPG 1167
            PG +GDKG+ G   P G  G+ G PG I    GK GP G  G RG  G  G  G  G PG
Sbjct: 982  PGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPG 1041

Query: 1168 IPG------YRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEP 1221
            +PG       RG  G PG SGLPG KG+ G   E S   G PGP+G+PG  G +G +G  
Sbjct: 1042 MPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEIS---GSPGPKGQPGESGFKGTKGRD 1098

Query: 1222 GAEG---YKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKP 1278
            G  G   + G+ G  G  G +G  G PG PG  G  G++GE G  G+ G +GA GP G P
Sbjct: 1099 GLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSP 1158

Query: 1279 GIPGLQGLLGPKGIQGYHGADGISGNPGKIGP-----PGKQGLPGIRGGPGRTGLA-GAP 1332
            G+ G +G  G  G+ G +G  G  G  G  GP     PG  GLPG +G  G  G+  GAP
Sbjct: 1159 GLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAP 1218

Query: 1333 GPPGVKGSSGLPGSPGIQGPKGEQGLPG---------QPGIQGKRGHRGAQGDQGPCGDP 1383
            G PG++G  G  G PG+QGP G  G PG         QPG  G+ G  G +G  GP G P
Sbjct: 1219 GKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPP 1278

Query: 1384 GLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPT 1443
            G  G     G  G  GF G PGPKGP+GD GI G SG  G +G +G     G  G +G  
Sbjct: 1279 GPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMR---GEPGFMGTP 1335

Query: 1444 GRTGPRGEKGFRGETGPQGPRGQPG----------------PPGPPGAPG 1477
            G+ GP G+ GF G  G  GPRG  G                PPGP G PG
Sbjct: 1336 GKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPG 1385



 Score =  731 bits (1886), Expect = 0.0
 Identities = 506/1293 (39%), Positives = 597/1293 (46%), Gaps = 307/1293 (23%)

Query: 487  LRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPG---PHGNPGLPGLPGPKGPKGDPGFSP 543
            L G KG+ G PG  GP G   P G +GP G+PG    +G PG PG PGP+GP G  G + 
Sbjct: 71   LSGLKGERGFPGLLGPYG---PKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNG 127

Query: 544  GQPVPGEKGDQGLSGLMGPPGMQGD--------------KGLKGHPGLPGL---PGEQGI 586
             Q   G  G  G  GL+GPPG+ G               KG+KG PGLPGL    G QG 
Sbjct: 128  TQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGA 187

Query: 587  PGFAGNIGSPGYPGRQGLAGPEGNPGP-----------KGAQGFIGSPGEA--------- 626
            PGF G +G  G PG QG  GP G  GP           KG +G +G PG A         
Sbjct: 188  PGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGEL 247

Query: 627  ----------GQLGPEGERGIPGIRGKKGF-----------KGRQGFPGDFGDRGP---A 662
                      G  G  G +G PGI G  GF           KG +G PG  G RGP    
Sbjct: 248  EFMGFPKGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSE 307

Query: 663  GLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGP--------MGLSGN------KG 708
            G+ G PG  G  G  GFPGL G  G  G  G  G+PGP          +SGN       G
Sbjct: 308  GVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPG 367

Query: 709  LPGIKGDKGEQGTAGELGEPGYP---GDKGAVGLPGPPGMRGKSGPSGQT-----GDPGL 760
            LPG+KGD+G QG  G  G PG P   G  GA+G  G PG++G  G  G+T     G PG 
Sbjct: 368  LPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGR 427

Query: 761  QGPSGPPGPEGFPG-----------DIGIPGQNGPEGPKGLLGNR--------------- 794
             G  GPPGP G P            + G PG  G +GPKG LG +               
Sbjct: 428  DGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGV 487

Query: 795  ---------GPPGP------PGLKGTQGE------EGPIGAFGELGPRGKPGQKGYAGEP 833
                     GPPGP      PGLKG +G+      +GP GA G +GP G  G KG  GEP
Sbjct: 488  PNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEP 547

Query: 834  ------GPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEK 887
                  G  G +G+ G QG  G IGE G  G+PG  G+ G  G+ G+ G PG  G  G  
Sbjct: 548  ILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQ-GFPGEKGLPGLP 606

Query: 888  GVMGYPGPPGVPGP-----IGPLGLPGHVGARGPPGSQGPKGQR---------GSRGPDG 933
            G  G+PGPPG+PG       GP GLPG  G  G PG QG  G +         GS GP G
Sbjct: 607  GEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSG 666

Query: 934  LLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPG 993
              G  G  G KG +G  G  G  G  G  G PG  G    P L G PG  G++GLPG PG
Sbjct: 667  FPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPG 726

Query: 994  L------------------RGLQGDV-----GPPGEMGMEGPPGTEGESGLQGEPGAKGD 1030
            L                  +G  GD+     G PGE G++G  G +G  G  G PG KG 
Sbjct: 727  LPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGV 786

Query: 1031 VGTAGSVGGTGE------PGLRGEPGAPGEE---GLQGKDGLKGVPGGRGL---PGEDGE 1078
             G  G +G  GE      PG  G+PG PG     G++GK GL G PG  G+   PG+ G 
Sbjct: 787  HGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGT 846

Query: 1079 KGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGE---VGSRGP 1135
            +G+ G PG I   G  G  GLPG  G+VG+ G  G PG  G     GP GE   VG  G 
Sbjct: 847  RGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGF 906

Query: 1136 PGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPK-------- 1187
            PG  G  G  G RG +G  G  G MGP G  G PG +G +G PGP G+P P+        
Sbjct: 907  PGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWL 966

Query: 1188 ----------GEKGYPGE--DSTVLGPPGP----------------RGEPGPVGDQGERG 1219
                      G  G+PG   D    G PGP                 G+PGP G  G RG
Sbjct: 967  KGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRG 1026

Query: 1220 EPGAEGYKGHVGVPGLRGATGQQ----------------------------GPPGEPGDQ 1251
             PG +G  G  G PG+ G +G Q                            G PG  G  
Sbjct: 1027 LPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQP 1086

Query: 1252 GEQGLKGERGSEG---------NKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGIS 1302
            GE G KG +G +G         NKG+ G  G SG  G+PG  G  G  G++G  G  G S
Sbjct: 1087 GESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSS 1146

Query: 1303 GNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGS--------SGLPGSPGIQGPKG 1354
            G+ G IGP G  GL G +G PG  GL G  G PG KG+        +G+PG  G+ GPKG
Sbjct: 1147 GHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKG 1206

Query: 1355 EQ-------GLPGQPGIQGKRGHRGAQGDQGPCGDPG---------LKGQPGEYGVQGLT 1398
            E+       G PG+PG++G++G RG  G QGP G PG         + GQPG+ G  GL 
Sbjct: 1207 EKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLD 1266

Query: 1399 GFQGFPGPKGP------------EGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRT 1446
            G +G PGP GP             GD G  GI GPKGP   +G+ G  G  G+ G  G  
Sbjct: 1267 GERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGP---KGDQGIPGFSGLPGELGLK 1323

Query: 1447 GPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPR 1479
            G RGE GF G  G  GP G PG PG  G  GPR
Sbjct: 1324 GMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPR 1356



 Score =  726 bits (1875), Expect = 0.0
 Identities = 493/1241 (39%), Positives = 582/1241 (46%), Gaps = 263/1241 (21%)

Query: 489  GPKGDTGP------------------PGPPGPAGIPGPSGKRGPRGIPGPHGNPGL---P 527
            GPKGD GP                  PGP GP G+ G +G +G  G PGP G PGL   P
Sbjct: 88   GPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPP 147

Query: 528  GLPGPKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIP 587
            GLPG KG KGDP  +PG    G KGD GL GL G  G QG  G  G  G  G PG QG P
Sbjct: 148  GLPGQKGSKGDPVLAPGS-FKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPP 206

Query: 588  GFAGNIGSPG-----YPGRQGLAGPEGNPGP----------------KGAQGFIGSPGEA 626
            G  G +G  G     + G +G+ G  G PGP                KG +G  G PG  
Sbjct: 207  GPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPK 266

Query: 627  GQLGPEGERGIPGI--RGKKGFKGRQGFPGDFGDRGPAG---LDGSPGLVGGTGPPGFPG 681
            G  G  G  G PG+   G+KG KG +G PG  G RGP G   + G PG  G  G  GFPG
Sbjct: 267  GFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPG 326

Query: 682  LRGSVGPVGPIGPAGIPGP--------MGLSGNKG------LPGIKGDKGEQGTAGELGE 727
            L G  G  G  G  G+PGP          +SGN G      LPG+KGD+G QG  G  G 
Sbjct: 327  LNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGV 386

Query: 728  PGYP---GDKGAVGLPGPPGMRGKSGPSGQT-----GDPGLQGPSGPPGPEGFPG----- 774
            PG P   G  GA+G  G PG++G  G  G+T     G PG  G  GPPGP G P      
Sbjct: 387  PGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFET 446

Query: 775  ------DIGIPGQNGPEGPKGLLGNRG------------------------PPGP----- 799
                  + G PG  G +GPKG LG +G                        PPGP     
Sbjct: 447  ETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIG 506

Query: 800  -PGLKGTQGE------EGPIGAFGELGPRGKPGQKGYAGEP------GPEGLKGEVGDQG 846
             PGLKG +G+      +GP GA G +GP G  G KG  GEP      G  G +G+ G QG
Sbjct: 507  LPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQG 566

Query: 847  NIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLG 906
              G IGE G  G+PG  G+ G  G+ G+ G PG  G  G  G  G+PGPPG+PG      
Sbjct: 567  FRGVIGEPGKDGVPGLPGLPGLPGDGGQ-GFPGEKGLPGLPGEKGHPGPPGLPG------ 619

Query: 907  LPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGD---QGKRGPHGLIGKTG 963
                    G PG  GP+G  G +G DGL G+QG+ G+KG        G  GP G  G  G
Sbjct: 620  -------NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPG 672

Query: 964  NPGERGFQGKPGLQGLPGSTGDRGLPGEPGL------------RGLQGDVGPPGEMGMEG 1011
             PG +G +G PG  G PGS+G +G PG PGL            RG +G  G PG  G +G
Sbjct: 673  FPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDG 732

Query: 1012 PPGTEGESGLQGEPGAKGDV--------GTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGL 1063
             PG  G  GL G  GA GD+        G  G  G TG  G  G+ G PG +G+ GK GL
Sbjct: 733  LPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGL 792

Query: 1064 KGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQ 1123
             G  G RG PG  G+ G+ G PG  GP G  G++GLPG  G    PG  G PGKKG +G+
Sbjct: 793  LGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGF---PGISGHPGKKGTRGK 849

Query: 1124 IGPTGEV---------------------GSRGPPGKIGKSGPKGARGTRGAVGHLGLMGP 1162
             GP G +                     GS G PG  G     G +G +G+VG +G  G 
Sbjct: 850  KGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGI 909

Query: 1163 DGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGE--------------------------D 1196
             G PGIPG RG +G PG +G  GP G  G PGE                          D
Sbjct: 910  PGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGD 969

Query: 1197 STVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGL-RGATGQQGPPGEPGDQGEQG 1255
                G  G  G PGP GD+GE G PG  G  G  G+PG+ +G +G+ GPPG  G +G  G
Sbjct: 970  KGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPG 1029

Query: 1256 LKG------------ERGSEGNKGKKGAPGPSGKPGI-------------PGLQGLLGPK 1290
            LKG            E GS+G +G  G PG SG PG+             PG +G  G  
Sbjct: 1030 LKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGES 1089

Query: 1291 GIQGYHGADGISGN---------PGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSS 1341
            G +G  G DG+ GN          GK+G  G  GLPG  G PG  G+ G PG PG  G  
Sbjct: 1090 GFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQ 1149

Query: 1342 GLPG---SPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPC-----GDPGLKGQPGEYG 1393
            G  G   SPG+ GPKG  G PG  G+ G  G +G  G  GP      G  GL G  GE G
Sbjct: 1150 GAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKG 1209

Query: 1394 VQGL-TGFQGFPGPKGPEGDAGIVGISGPKGPIGH---------RGNTGPLGREGIIGPT 1443
              G+  G  G PG +G +GD G  G+ GP G  G           G  G  GR G+ G  
Sbjct: 1210 YPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGER 1269

Query: 1444 GRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQMDI 1484
            GR GP G  G  G +  QG  G PG PG PG  GP+    I
Sbjct: 1270 GRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGI 1310



 Score =  725 bits (1871), Expect = 0.0
 Identities = 449/1041 (43%), Positives = 538/1041 (51%), Gaps = 111/1041 (10%)

Query: 489  GPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGP------KGDPGFS 542
            GP G+ GPPGP G  G+PG  G RG RG  G  G  G PGL GP GP      KG+P  S
Sbjct: 491  GPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILS 550

Query: 543  PGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQ 602
              Q +PG++GD G  G  G  G  G  G+ G PGLPGLPG+       G  G PG  G  
Sbjct: 551  TIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGD-------GGQGFPGEKGLP 603

Query: 603  GLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPA 662
            GL G +G+PGP G  G        G  G  G RG+PG +GK G  G+QG PG  G   P 
Sbjct: 604  GLPGEKGHPGPPGLPG-------NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPC 656

Query: 663  GLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTA 722
             + GS G  G  G PGFPG +GS                GL G  G PG  G KGE G+ 
Sbjct: 657  IIPGSYGPSGFPGTPGFPGPKGS---------------RGLPGTPGQPGSSGSKGEPGSP 701

Query: 723  G--ELGE-PGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIP 779
            G   L E PG+PG +G  GLPG PG+ GK G  G  G PGL G  G  G + F  + G P
Sbjct: 702  GLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATG-DIFGAENGAP 760

Query: 780  GQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLK 839
            G+ G +G  G  G  G  G PGLKG  G+ G +G  GE G  G PGQ G  G PG     
Sbjct: 761  GEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPG----- 815

Query: 840  GEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVP 899
                  G  G  G++G  G PG  G++G  G+KG RG  GP G   +KG+ G  G PG P
Sbjct: 816  ----SSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNP 871

Query: 900  GPIGPLGLPGHVGARGPPGSQGPKGQRGSRGP---DGLLGEQGIQGAKGEKGDQGKRGPH 956
            G +G  G PG  G  G P   GPKG++GS G     G+ G  GI G +G KG  G  G  
Sbjct: 872  GLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKM 931

Query: 957  GLIGKTGNPGERGFQGKPGLQGLP---------------GSTGDRGLPGEPGLRGLQGDV 1001
            G  G+ G PGE+G +G PG  G+P               GS G  G  G PG RG +G+ 
Sbjct: 932  GPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEA 991

Query: 1002 GPPGEMGMEGPPGTEGE-SGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGK 1060
            G PG  G+ G PG  G   G+ G+PG  G +G  G  G  G  G+ G PG PGE G QG 
Sbjct: 992  GRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGI 1051

Query: 1061 DGLKGVPGGRGLPGEDGEKGE-MGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKG 1119
             G  G+PG  GLPG  G+ G+ + + G  GP G+ G++G  G +G  G+ G  G PG KG
Sbjct: 1052 RGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKG 1111

Query: 1120 DKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPG 1179
            + G++G +G+VG  G PG  G +G +G  G  G+ GH G +GP G PG+ G +G  G PG
Sbjct: 1112 EDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPG 1171

Query: 1180 P---SGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQG-------ERGEPGAEGYKGH 1229
                +GLPG KG  G PG   T  G PGP G PGP G++G         G+PG  G KG 
Sbjct: 1172 LHGLNGLPGTKGTHGTPGPSIT--GVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGD 1229

Query: 1230 VGVPGLRGATGQQGPPG---------EPGDQGEQGLKGERGSEGNKGKKGAPGPS---GK 1277
             G PGL+G  G  G PG         +PGD G  GL GERG  G  G  G PGPS   G 
Sbjct: 1230 RGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGD 1289

Query: 1278 PGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGV 1337
             G PG  G+ GPKG +G  G  G SG PG++G  G +G PG  G PG+ G  G PG PG+
Sbjct: 1290 TGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGM 1349

Query: 1338 K------GSSGLPGSPG-------IQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPG 1384
            K      GSSGL G PG       +Q P G  GLPG  GI G  G  GAQG  G  G  G
Sbjct: 1350 KGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKG 1409

Query: 1385 LKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTG 1444
            L G PG+ G  GL      PGP G  GD G+ G+ GP G  G  G  GP G  G+ G + 
Sbjct: 1410 LPGIPGKDGPSGL------PGPPGALGDPGLPGLQGPPGFEGAPGQQGPFGMPGMPGQSM 1463

Query: 1445 RTGPRGEKGFRGETGPQGPRG 1465
            R G    K  + E  P  P G
Sbjct: 1464 RVGYTLVKHSQSEQVPPCPIG 1484



 Score =  701 bits (1808), Expect = 0.0
 Identities = 468/1171 (39%), Positives = 548/1171 (46%), Gaps = 221/1171 (18%)

Query: 519  GPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLP 578
            G  G PG  G+ GP GP+G   F+    + G KG++G  GL+GP G +GDKG  G PG  
Sbjct: 46   GARGRPGPIGIQGPTGPQG---FTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFL 102

Query: 579  GLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGI- 637
            G+ G  G PG  G  G PG  G  G  G  G PGP G  G +G PG  GQ G +G+  + 
Sbjct: 103  GINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLA 162

Query: 638  PGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGI 697
            PG    KG KG  G PG  G  GP G  G PG VG  GPPG  G  G  GP+GP G  G+
Sbjct: 163  PG--SFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGL 220

Query: 698  --PGPMGLSGNKGLPGIKG-------------DKGEQGTAGELGEPGYPGDKGAVGLPGP 742
               G  G+ G+ GLPG  G              KG++G+ GE G  G+PG  G  G PG 
Sbjct: 221  GFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFPG- 279

Query: 743  PGMRGKSGPSGQTGDPGLQGP---------SGPPGPEGFPGDIGIPGQNGPEGPKG---- 789
             G  G+ G  G+ G PGL GP          GPPG +G  G +G PG NG +G +G    
Sbjct: 280  LGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGD 339

Query: 790  ----------------LLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEP 833
                            + GN G PG PGL G +G+EG  G  G  G  G P   G  G  
Sbjct: 340  IGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGAL 399

Query: 834  GPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKG--------------ERGSPG 879
            GP+G  G  GDQGN G+    G  GLPG  G+ G  G  G              E G PG
Sbjct: 400  GPQGFPGLKGDQGNPGRT-TIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPG 458

Query: 880  PLGPQGEKGVMGY---------------------PGPPGVPGPIGPLGLPGHVGARGPPG 918
              G QG KG +G                      PG PG PGP G +GLPG  GARG  G
Sbjct: 459  LRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRG 518

Query: 919  S---QGPKGQRGSRGPDGLLGEQG---------IQGAKGEKGDQGKRGPHGLIGKTGN-- 964
            S   QGP G  G  GP G  G +G         IQG  G++GD G +G  G+IG+ G   
Sbjct: 519  SGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDG 578

Query: 965  ---------------------------PGERGFQGKPGL--QGLPGSTGDRGLPGEPGLR 995
                                       PGE+G  G PGL   GLPG  G RGLPG+ G  
Sbjct: 579  VPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKD 638

Query: 996  GLQGDVGPPGEMGM---------------EGPPGTEGESGLQGEPGAKGDVGTAGSVGGT 1040
            GL G  G PG  G+                G PG  G  G +G PG  G  G++GS G  
Sbjct: 639  GLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEP 698

Query: 1041 GEPGL------------RGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKG-----EMG 1083
            G PGL            RGE G PG  GL GKDGL G+ G  GLPG  G  G     E G
Sbjct: 699  GSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENG 758

Query: 1084 LPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSG 1143
             PG  G  G +G  G  G  G+ G+ G  G+PG  G KG+ G  G  G  G PG  G SG
Sbjct: 759  APGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSG 818

Query: 1144 PKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPG---PSGLPGPKGEKGYPGEDSTVL 1200
            P G +G  G  G  G  G  G PG  G RG +G PG     GLPG KG  G PG    ++
Sbjct: 819  PYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPG----LV 874

Query: 1201 GPPGPRGEPGPVG---DQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLK 1257
            G  G  G PG  G     G +GE G+ G+ G  G+PGL G  G +G  G PG  G+ G  
Sbjct: 875  GLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPS 934

Query: 1258 GERGSEGNKGKKGAPGPSGKP------------GIPGLQGLLGPKGIQGYHGADGISGNP 1305
            G  G+ G KG +G PGP G P            G  G QG  G  G  G  G  G +G P
Sbjct: 935  GRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRP 994

Query: 1306 GKIGPPGKQGLPGI----RGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQ 1361
            G  G PG  GLPGI     G PG  G  G  G PG+KGSSG+ G PG+ G  G QG+ G 
Sbjct: 995  GPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGS 1054

Query: 1362 PGIQGKRGHRGAQGDQGP----CGDPGLKGQPGEYGVQ------GLTGFQGFPGPKGPEG 1411
            PG+ G  G  G +GD G      G PG KGQPGE G +      GL G  GFPG KG +G
Sbjct: 1055 PGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDG 1114

Query: 1412 DAGI---VGISGP---------------KGPIGHRGNTGPLGREGIIGPTGRTGPRGEKG 1453
              G+   VG+ G                 G  GH+G  GPLG  G+IGP G  G  G  G
Sbjct: 1115 KVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHG 1174

Query: 1454 FRGETGPQGPRGQPGP-----PGPPGAPGPR 1479
              G  G +G  G PGP     PGP G PGP+
Sbjct: 1175 LNGLPGTKGTHGTPGPSITGVPGPAGLPGPK 1205



 Score =  607 bits (1564), Expect = e-173
 Identities = 395/930 (42%), Positives = 459/930 (49%), Gaps = 102/930 (10%)

Query: 643  KKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMG 702
            +KG +GR G  G  G  GP G  GS GL G  G  GFPGL G  GP G  GP G+PG +G
Sbjct: 44   EKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLG 103

Query: 703  LS---GNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGP-------- 751
            ++   G+ G PG +G  G  G  G  G  G+PG  G  GL GPPG+ G+ G         
Sbjct: 104  INGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAP 163

Query: 752  ---SGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGT--- 805
                G  GDPGL G  G  GP+G P   G PG  GP GP GL G  GPPGP G  G    
Sbjct: 164  GSFKGMKGDPGLPGLDGITGPQGAP---GFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGL 220

Query: 806  --QGEEGPIGAFGELGPRGKPGQKGYAGEPG-PEGLKGEVGDQGNIGKIGETGPVGLPGE 862
              QGE+G  G  G  GP G P   G     G P+G KG  G+ G  G  G +GP G PG 
Sbjct: 221  GFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFPG- 279

Query: 863  VGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGP 922
            +G TG  GEKGE+G PG  GP+G  G  G  GPPG  G  G LG P   G  G  G +G 
Sbjct: 280  LGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFP---GLNGFQGIEGQ 336

Query: 923  KGQRGSRGPD--------------GLLGEQGIQGAKGEKGDQGKRGPHGLIG---KTGNP 965
            KG  G  GPD              G  G  G+ G KG++G QG RGP G+ G    +G P
Sbjct: 337  KGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVP 396

Query: 966  GERGFQGKPGL---QGLPGST--GDRGLPGEPGLRGLQGDVGPPG-----------EMGM 1009
            G  G QG PGL   QG PG T  G  GLPG  GL G  G  GPP            E G 
Sbjct: 397  GALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGF 456

Query: 1010 EGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGG 1069
             G  G +G  G  G  G KGD G     GG    G  GEPG PG  GL G  GLKG  G 
Sbjct: 457  PGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGD 516

Query: 1070 RGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGE 1129
            RG  G  G  G  GL G +GP G  G+ G P    I G+PG RG  G +G +G IG  G+
Sbjct: 517  RGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGK 576

Query: 1130 VGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGH--QGQPGPSGLPGPK 1187
             G  G PG  G  G  G +G  G  G  GL G  G PG PG  G+   G PGP GLPG K
Sbjct: 577  DGVPGLPGLPGLPG-DGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGDK 635

Query: 1188 GEKGYPGEDSTVLGPPGPR---------GEPGPVGDQGERGEPGAEGYKGHVGVPGLRGA 1238
            G+ G PG+     G PG +         G  GP G  G  G PG +G +G  G PG  G+
Sbjct: 636  GKDGLPGQQ----GLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGS 691

Query: 1239 TGQQGPPGE---------PGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLG- 1288
            +G +G PG          PG  G +G KG  G  G  GK G PG  G PG+PG +G  G 
Sbjct: 692  SGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGD 751

Query: 1289 ----PKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLP 1344
                  G  G  G  G++G+ G +G  G  GL G+ G PG  G  G  G PG  G  G P
Sbjct: 752  IFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQP 811

Query: 1345 GSPGIQGP---KGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQ 1401
            G+PG  GP   KG+ GLPG PG  G  GH G +G +G  G PG   + G  G++GL G  
Sbjct: 812  GTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNP 871

Query: 1402 GFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQ 1461
            G  G KG  G  G+ G+    GP G +G+ G +G  GI G  G  G RG KG  G TG  
Sbjct: 872  GLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKM 931

Query: 1462 GP---------RGQPGPPGPPGAPGPRKQM 1482
            GP         +G  G PGP G P PR+ M
Sbjct: 932  GPSGRAGTPGEKGDRGNPGPVGIPSPRRPM 961



 Score =  489 bits (1260), Expect = e-138
 Identities = 326/832 (39%), Positives = 398/832 (47%), Gaps = 167/832 (20%)

Query: 804  GTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPE---------GLKGEVGDQGNIGKI--- 851
            G Q   G    F E G RG+PG  G  G  GP+         GLKGE G  G +G     
Sbjct: 31   GGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPK 90

Query: 852  GETGPVGLPGEVGMT---GSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLP 908
            G+ GP+G+PG +G+    G  G+ G RG PG  G  G +G +G+PGP G PG +GP GLP
Sbjct: 91   GDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLP 150

Query: 909  GH-----------------------------------------VGARGPPGSQGPKGQRG 927
            G                                          VG  GPPG QGP G  G
Sbjct: 151  GQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPG 210

Query: 928  SRGPDGLLGEQGIQGAKGEKGDQGKRGPHG-------------LIGKTGNPGERGFQGKP 974
              GPDG +G  G QG KG KGD G  GP G               GK G+ GE G +G P
Sbjct: 211  PLGPDGNMG-LGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFP 269

Query: 975  GLQGLP-----GSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGE---------SG 1020
            G+ G P     G+TG++G  GE G+ GL G  GP G  G++GPPG +G+         +G
Sbjct: 270  GISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNG 329

Query: 1021 LQGEPGAKGDVGTAGS-----------VGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGG 1069
             QG  G KGD+G  G             G  G+PG+ G PG  G+EG+QG  G  GVPG 
Sbjct: 330  FQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGL 389

Query: 1070 RGLPGEDGEKGEMGLPGIIGPLGRSGQT-----GLPGPEGIVGIPGQRGRPGKKGD---- 1120
              L G  G  G  G PG+ G  G  G+T     GLPG +G+ G PG  G P  + +    
Sbjct: 390  PALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETL 449

Query: 1121 -KGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEP---------GIPG 1170
               + G  G  G +GP G +G  G KG  G     G +   GP GEP         G+PG
Sbjct: 450  HNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPG 509

Query: 1171 YRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPG-PV-----GDQGERGEPGAE 1224
             +G +G  G  G  GP G  G  G     LGP GP+G+ G P+     G  G+RG+ G++
Sbjct: 510  LKGARGDRGSGGAQGPAGAPGLVGP----LGPSGPKGKKGEPILSTIQGMPGDRGDSGSQ 565

Query: 1225 GYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQ 1284
            G++G +G PG  G  G  G PG PGD G QG  GE+G  G  G+KG PGP G PG  GL 
Sbjct: 566  GFRGVIGEPGKDGVPGLPGLPGLPGD-GGQGFPGEKGLPGLPGEKGHPGPPGLPG-NGLP 623

Query: 1285 GLLGPKGIQGYHGADGISGN---------------PGKIGPPGKQGLPGIRGGPGRTGLA 1329
            GL GP+G+ G  G DG+ G                PG  GP G  G PG  G  G  GL 
Sbjct: 624  GLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLP 683

Query: 1330 GAPGPPGVKGSSGLPGSPGI---------QGPKGEQGLPGQPGIQGKRGHRGAQGDQGPC 1380
            G PG PG  GS G PGSPG+          GP+GE+GLPG PG+ GK G  G  G  G  
Sbjct: 684  GTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLP 743

Query: 1381 GDPGL--------KGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTG 1432
            G  G          G PGE G+QGLTG +GF G  G  G  G+ G  G  GP G RG+ G
Sbjct: 744  GSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPG 803

Query: 1433 PLGREGIIGPTGRTGPRGEK---------GFRGETGPQGPRGQPGPPGPPGA 1475
              G+ G  G  G +GP G K         GF G +G  G +G  G  GPPG+
Sbjct: 804  TPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGS 855



 Score =  437 bits (1123), Expect = e-122
 Identities = 288/736 (39%), Positives = 339/736 (46%), Gaps = 124/736 (16%)

Query: 865  MTGSIGEKGERGSPGPLGPQG---------EKGVMGYPGPPGVPGPIGP------LGLPG 909
            +T  +   GE+    P G Q          EKG  G PGP G+ GP GP       GL G
Sbjct: 14   LTEELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSG 73

Query: 910  HVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERG 969
              G RG PG  GP G +G +GP G+ G  GI G  G  G  G RGP GL G  G  G  G
Sbjct: 74   LKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVG 133

Query: 970  FQGKPGLQGLPGSTGDRGLP--------------------GEPGLRGLQGDVGP------ 1003
            F   PG  G PG  G  GLP                    G+PGL GL G  GP      
Sbjct: 134  F---PGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGF 190

Query: 1004 PGEMGMEGPPGTEGES--------------GLQGEPGAKGDVGTAGSVG---GTGEPGLR 1046
            PG +G  GPPG +G                G QGE G KGDVG  G  G    TGE    
Sbjct: 191  PGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFM 250

Query: 1047 GEP----GAPGEEGLQGKDGLKGVPG--GRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLP 1100
            G P    G+ GE G +G  G+ G PG  G G  GE GEKGE G+PG+ GP G  G  G+ 
Sbjct: 251  GFPKGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQ 310

Query: 1101 GPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGP-----------PGKIGKSGPKGARG 1149
            GP G  G  G  G PG  G +G  G  G++G  GP            G  G  G  G  G
Sbjct: 311  GPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPG 370

Query: 1150 TRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDST----------V 1199
             +G  G  GL GP G PG+P   G  G  GP G PG KG++G PG  +           +
Sbjct: 371  LKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGL 430

Query: 1200 LGPPGPRGEPGPV-----------------GDQGERGEPGAEGYKGHVGVPGLRGATGQQ 1242
             GPPGP G P P                  G+QG +G  G +G KG  G     G     
Sbjct: 431  PGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNT 490

Query: 1243 GPPGEPGDQGEQ---GLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGAD 1299
            GPPGEPG  G     GL G +G+ G++G  GA GP+G PG+ G  G  GPKG +G     
Sbjct: 491  GPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILS 550

Query: 1300 GISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGV--KGSSGLPGSPGIQGPKGEQG 1357
             I G PG  G  G QG  G+ G PG+ G+ G PG PG+   G  G PG  G+ G  GE+G
Sbjct: 551  TIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKG 610

Query: 1358 LPGQPGIQGK-----RGHRGAQGDQGPCGDPGLKGQPGEYGV---------QGLTGFQGF 1403
             PG PG+ G       G RG  GD+G  G PG +G PG  G+          G +GF G 
Sbjct: 611  HPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGT 670

Query: 1404 PGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGP 1463
            PG  GP+G  G+ G  G  G  G +G  G  G   +    G  GPRGEKG  G  G  G 
Sbjct: 671  PGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGK 730

Query: 1464 RGQPGPPGPPGAPGPR 1479
             G PG  G PG PG +
Sbjct: 731  DGLPGMIGSPGLPGSK 746



 Score =  390 bits (1003), Expect = e-108
 Identities = 264/694 (38%), Positives = 326/694 (46%), Gaps = 111/694 (15%)

Query: 896  PGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGP 955
            PG+   +  L L   + A G      P G +   G      E+G +G  G  G QG  GP
Sbjct: 3    PGLWLLLVTLCLTEELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGP 62

Query: 956  HGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGT 1015
             G  G TG  G +G +G PGL G  G  GD+G  G PG  G+ G  G PG+ G  GPPG 
Sbjct: 63   QGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGL 122

Query: 1016 EGESGLQGE---------PGAKGDVGTAGSVGGTGEP--------GLRGEPGAPGEEGLQ 1058
            +G +G QG          PG  G  G  G  G  G+P        G++G+PG PG +G+ 
Sbjct: 123  DGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGIT 182

Query: 1059 GKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQ--TGLPGPEGIVGIPGQRGRP- 1115
            G  G  G PG  G  G  G +G  G PG +GP G  G    G  G +G VG+PG  G P 
Sbjct: 183  GPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPP 242

Query: 1116 ------------GKKGDKGQIGPTGEVGSRGPPG--KIGKSGPKGARGTRGAVGHLGLMG 1161
                        GKKG KG+ GP G  G  GPPG   +G +G KG +G +G  G  G  G
Sbjct: 243  STGELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRG 302

Query: 1162 PDGEPGIPGYRGHQGQPGPSGLP---------GPKGEKGYPGED-------STVLGPPGP 1205
            P G  G+ G  G QG+ G  G P         G KG+ G PG D       + + G PG 
Sbjct: 303  PMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGD 362

Query: 1206 RGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGER--GSE 1263
             G PG  G +G+ G  G  G  G  G+P L G  G  GP G PG +G+QG  G    G+ 
Sbjct: 363  PGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAA 422

Query: 1264 GNKGKKGAPGPSGKP-----------------GIPGLQGLLGPKGIQGYHGADGIS---- 1302
            G  G+ G PGP G P                 G PGL+G  GPKG  G  G  G S    
Sbjct: 423  GLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCA 482

Query: 1303 --------GNPGKIGPPGKQ---GLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQG 1351
                    G PG+ GPPG     GLPG++G  G  G  GA GP G  G  G  G  G +G
Sbjct: 483  CDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKG 542

Query: 1352 PKGE------QGLPGQPGIQGKRGHRGAQGDQGPCGDPGL-----------KGQPGEYGV 1394
             KGE      QG+PG  G  G +G RG  G+ G  G PGL           +G PGE G+
Sbjct: 543  KKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGL 602

Query: 1395 QGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRT-------- 1446
             GL G +G PGP G  G+ G+ G+ GP+G  G +G  G  G++G+ G  G T        
Sbjct: 603  PGLPGEKGHPGPPGLPGN-GLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGS 661

Query: 1447 -GPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPR 1479
             GP G  G  G  GP+G RG PG PG PG+ G +
Sbjct: 662  YGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSK 695



 Score =  376 bits (966), Expect = e-104
 Identities = 243/600 (40%), Positives = 292/600 (48%), Gaps = 87/600 (14%)

Query: 488  RGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGN---PGLPGLPGPKGPKGDPGF--- 541
            +G KG  G  G PG  G+PG  G RG +GIPG  G     G  G PG KG +G+PG    
Sbjct: 895  KGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGI 954

Query: 542  -SPGQPVP-----GEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNI-G 594
             SP +P+      G+KG QG +G  G PG +GDKG  G PG PGLPG  G+PG    + G
Sbjct: 955  PSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSG 1014

Query: 595  SPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQG--- 651
             PG PG  G+ G  G  G  G  GF G PGE+G  G  G  G+PG  G  G KG  G   
Sbjct: 1015 KPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTV 1074

Query: 652  ----FPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMG---LS 704
                 PG  G  G +G  G+ G  G  G  GFPG +G  G VG  G  G+PG  G   ++
Sbjct: 1075 EISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVA 1134

Query: 705  GNKGLPGIKGDKGEQGTAGELGEPGY------------------PGDKGAVGLPGP---- 742
            G +G PG+ G  G QG  G LG PG                   PG KG  G PGP    
Sbjct: 1135 GMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITG 1194

Query: 743  -PGMRGKSGPSGQTGDPGLQ-GPSGPPGPEGFPGDIGIPGQNGPEG---------PKGLL 791
             PG  G  GP G+ G PG+  G  G PG  G  GD G PG  GP G         P  + 
Sbjct: 1195 VPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIA 1254

Query: 792  GNRGPPGPPGLKGTQGEEGPIGAFGELGP---RGKPGQKGYAGEPGPEGLKGEVGDQGNI 848
            G  G PG PGL G +G  GP G  G  GP   +G  G  G+ G PGP+G KG+ G  G  
Sbjct: 1255 GQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFS 1314

Query: 849  GKIGETGPVGL---PGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPG-------V 898
            G  GE G  G+   PG +G  G +G  G+ G PG  G  G +G  G  G PG       V
Sbjct: 1315 GLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAV 1374

Query: 899  PGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGL 958
              P GPLGLP      G  G  G  G  G++GP GL G +G+ G  G+ G  G  GP G 
Sbjct: 1375 QVPPGPLGLP------GIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGA 1428

Query: 959  IGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPG---------LRGLQGDVGPPGEMGM 1009
            +   G+PG  G QG PG +G PG  G  G+PG PG         ++  Q +  PP  +GM
Sbjct: 1429 L---GDPGLPGLQGPPGFEGAPGQQGPFGMPGMPGQSMRVGYTLVKHSQSEQVPPCPIGM 1485



 Score =  188 bits (477), Expect = 4e-47
 Identities = 122/277 (44%), Positives = 142/277 (51%), Gaps = 27/277 (9%)

Query: 487  LRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGL------PGPKGPKGDPG 540
            LRG KGD G PG  GPAG+PG  G   P  I G  G+PG PGL      PGP GP G PG
Sbjct: 1223 LRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPG 1282

Query: 541  FSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPG---LPGEQGIPGFAGNIGSPG 597
             S  Q   G+ GD G  G+ GP G +GD+G+ G  GLPG   L G +G PGF G  G  G
Sbjct: 1283 PSSNQ---GDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVG 1339

Query: 598  YPGRQGLAGPEGNPGPKGAQGFIGSPG-----EAGQLGPEGERGIPGIRGKKGFKGRQGF 652
             PG  G  G +G  GP+G+ G  G PG     EA Q+ P G  G+PGI       G  G 
Sbjct: 1340 PPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQV-PPGPLGLPGI------DGIPGL 1392

Query: 653  PGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGI 712
             GD G +GP GL GS GL    G PG  G  G  GP G +G  G+PG  G  G +G PG 
Sbjct: 1393 TGDPGAQGPVGLQGSKGL---PGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPGQ 1449

Query: 713  KGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKS 749
            +G  G  G  G+    GY   K +     PP   G S
Sbjct: 1450 QGPFGMPGMPGQSMRVGYTLVKHSQSEQVPPCPIGMS 1486


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.141    0.437 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 102,906,402
Number of Sequences: 37866
Number of extensions: 7867924
Number of successful extensions: 278036
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 329
Number of HSP's successfully gapped in prelim test: 1086
Number of HSP's that attempted gapping in prelim test: 26333
Number of HSP's gapped (non-prelim): 29239
length of query: 1714
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1598
effective length of database: 13,855,062
effective search space: 22140389076
effective search space used: 22140389076
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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